data_3SWW # _entry.id 3SWW # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3SWW RCSB RCSB066753 WWPDB D_1000066753 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 3BJM ;Crystal structure of human DPP-IV in complex with (1S,3S, 5S)-2-[(2S)-2-AMINO-2-(3-HYDROXYTRICYCLO[3.3.1.13,7]DEC-1- YL)ACETYL]-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE (CAS), (1S,3S,5S)-2-((2S)-2-AMINO-2-(3-HYDROXYADAMANTAN-1- YL)ACETYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBONITRILE (IUPAC), OR BMS-477118 ; unspecified PDB 3NOX ;Crystal structure of human DPP-IV in complex with Sa-(+)-(6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidin-2-yl)(morpholino)methanone ; unspecified PDB 3SWW . unspecified PDB 3Q0T . unspecified # _pdbx_database_status.entry_id 3SWW _pdbx_database_status.status_code REL _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2011-07-14 _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.status_code_cs ? _pdbx_database_status.pdb_format_compatible Y # _audit_author.name 'Klei, H.E.' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title ;7-Oxopyrrolopyridine-derived DPP4 inhibitors-mitigation of CYP and hERG liabilities via introduction of polar functionalities in the active site. ; _citation.journal_abbrev Bioorg.Med.Chem.Lett. _citation.journal_volume 21 _citation.page_first 6646 _citation.page_last 6651 _citation.year 2011 _citation.journal_id_ASTM BMCLE8 _citation.country UK _citation.journal_id_ISSN 0960-894X _citation.journal_id_CSD 1127 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 21996520 _citation.pdbx_database_id_DOI 10.1016/j.bmcl.2011.09.074 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Wang, W.' 1 primary 'Devasthale, P.' 2 primary 'Wang, A.' 3 primary 'Harrity, T.' 4 primary 'Egan, D.' 5 primary 'Morgan, N.' 6 primary 'Cap, M.' 7 primary 'Fura, A.' 8 primary 'Klei, H.E.' 9 primary 'Kish, K.' 10 primary 'Weigelt, C.' 11 primary 'Sun, L.' 12 primary 'Levesque, P.' 13 primary 'Li, Y.X.' 14 primary 'Zahler, R.' 15 primary 'Kirby, M.S.' 16 primary 'Hamann, L.G.' 17 # _cell.length_a 65.534 _cell.length_b 67.928 _cell.length_c 423.472 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3SWW _cell.pdbx_unique_axis ? _cell.Z_PDB 8 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.entry_id 3SWW _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.Int_Tables_number 19 _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Dipeptidyl peptidase 4' 87450.844 2 3.4.14.5 ? 'unp residues 39-766' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 14 ? ? ? ? 3 non-polymer syn '3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyethyl)-2-methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one' 380.268 2 ? ? ? ? 4 water nat water 18.015 431 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name ;ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, Dipeptidyl peptidase 4 membrane form, Dipeptidyl peptidase IV membrane form, Dipeptidyl peptidase 4 soluble form, Dipeptidyl peptidase IV soluble form ; # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;EFSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILL EYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYN GITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSL SSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGR FRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQL SDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDF IILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINR RLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTP EDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMS HFIKQCFSLPPLEQKLISEEDLNSAVDHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;EFSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILL EYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYN GITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSL SSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGR FRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQL SDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDF IILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINR RLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTP EDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMS HFIKQCFSLPPLEQKLISEEDLNSAVDHHHHHH ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLU n 1 2 PHE n 1 3 SER n 1 4 ARG n 1 5 LYS n 1 6 THR n 1 7 TYR n 1 8 THR n 1 9 LEU n 1 10 THR n 1 11 ASP n 1 12 TYR n 1 13 LEU n 1 14 LYS n 1 15 ASN n 1 16 THR n 1 17 TYR n 1 18 ARG n 1 19 LEU n 1 20 LYS n 1 21 LEU n 1 22 TYR n 1 23 SER n 1 24 LEU n 1 25 ARG n 1 26 TRP n 1 27 ILE n 1 28 SER n 1 29 ASP n 1 30 HIS n 1 31 GLU n 1 32 TYR n 1 33 LEU n 1 34 TYR n 1 35 LYS n 1 36 GLN n 1 37 GLU n 1 38 ASN n 1 39 ASN n 1 40 ILE n 1 41 LEU n 1 42 VAL n 1 43 PHE n 1 44 ASN n 1 45 ALA n 1 46 GLU n 1 47 TYR n 1 48 GLY n 1 49 ASN n 1 50 SER n 1 51 SER n 1 52 VAL n 1 53 PHE n 1 54 LEU n 1 55 GLU n 1 56 ASN n 1 57 SER n 1 58 THR n 1 59 PHE n 1 60 ASP n 1 61 GLU n 1 62 PHE n 1 63 GLY n 1 64 HIS n 1 65 SER n 1 66 ILE n 1 67 ASN n 1 68 ASP n 1 69 TYR n 1 70 SER n 1 71 ILE n 1 72 SER n 1 73 PRO n 1 74 ASP n 1 75 GLY n 1 76 GLN n 1 77 PHE n 1 78 ILE n 1 79 LEU n 1 80 LEU n 1 81 GLU n 1 82 TYR n 1 83 ASN n 1 84 TYR n 1 85 VAL n 1 86 LYS n 1 87 GLN n 1 88 TRP n 1 89 ARG n 1 90 HIS n 1 91 SER n 1 92 TYR n 1 93 THR n 1 94 ALA n 1 95 SER n 1 96 TYR n 1 97 ASP n 1 98 ILE n 1 99 TYR n 1 100 ASP n 1 101 LEU n 1 102 ASN n 1 103 LYS n 1 104 ARG n 1 105 GLN n 1 106 LEU n 1 107 ILE n 1 108 THR n 1 109 GLU n 1 110 GLU n 1 111 ARG n 1 112 ILE n 1 113 PRO n 1 114 ASN n 1 115 ASN n 1 116 THR n 1 117 GLN n 1 118 TRP n 1 119 VAL n 1 120 THR n 1 121 TRP n 1 122 SER n 1 123 PRO n 1 124 VAL n 1 125 GLY n 1 126 HIS n 1 127 LYS n 1 128 LEU n 1 129 ALA n 1 130 TYR n 1 131 VAL n 1 132 TRP n 1 133 ASN n 1 134 ASN n 1 135 ASP n 1 136 ILE n 1 137 TYR n 1 138 VAL n 1 139 LYS n 1 140 ILE n 1 141 GLU n 1 142 PRO n 1 143 ASN n 1 144 LEU n 1 145 PRO n 1 146 SER n 1 147 TYR n 1 148 ARG n 1 149 ILE n 1 150 THR n 1 151 TRP n 1 152 THR n 1 153 GLY n 1 154 LYS n 1 155 GLU n 1 156 ASP n 1 157 ILE n 1 158 ILE n 1 159 TYR n 1 160 ASN n 1 161 GLY n 1 162 ILE n 1 163 THR n 1 164 ASP n 1 165 TRP n 1 166 VAL n 1 167 TYR n 1 168 GLU n 1 169 GLU n 1 170 GLU n 1 171 VAL n 1 172 PHE n 1 173 SER n 1 174 ALA n 1 175 TYR n 1 176 SER n 1 177 ALA n 1 178 LEU n 1 179 TRP n 1 180 TRP n 1 181 SER n 1 182 PRO n 1 183 ASN n 1 184 GLY n 1 185 THR n 1 186 PHE n 1 187 LEU n 1 188 ALA n 1 189 TYR n 1 190 ALA n 1 191 GLN n 1 192 PHE n 1 193 ASN n 1 194 ASP n 1 195 THR n 1 196 GLU n 1 197 VAL n 1 198 PRO n 1 199 LEU n 1 200 ILE n 1 201 GLU n 1 202 TYR n 1 203 SER n 1 204 PHE n 1 205 TYR n 1 206 SER n 1 207 ASP n 1 208 GLU n 1 209 SER n 1 210 LEU n 1 211 GLN n 1 212 TYR n 1 213 PRO n 1 214 LYS n 1 215 THR n 1 216 VAL n 1 217 ARG n 1 218 VAL n 1 219 PRO n 1 220 TYR n 1 221 PRO n 1 222 LYS n 1 223 ALA n 1 224 GLY n 1 225 ALA n 1 226 VAL n 1 227 ASN n 1 228 PRO n 1 229 THR n 1 230 VAL n 1 231 LYS n 1 232 PHE n 1 233 PHE n 1 234 VAL n 1 235 VAL n 1 236 ASN n 1 237 THR n 1 238 ASP n 1 239 SER n 1 240 LEU n 1 241 SER n 1 242 SER n 1 243 VAL n 1 244 THR n 1 245 ASN n 1 246 ALA n 1 247 THR n 1 248 SER n 1 249 ILE n 1 250 GLN n 1 251 ILE n 1 252 THR n 1 253 ALA n 1 254 PRO n 1 255 ALA n 1 256 SER n 1 257 MET n 1 258 LEU n 1 259 ILE n 1 260 GLY n 1 261 ASP n 1 262 HIS n 1 263 TYR n 1 264 LEU n 1 265 CYS n 1 266 ASP n 1 267 VAL n 1 268 THR n 1 269 TRP n 1 270 ALA n 1 271 THR n 1 272 GLN n 1 273 GLU n 1 274 ARG n 1 275 ILE n 1 276 SER n 1 277 LEU n 1 278 GLN n 1 279 TRP n 1 280 LEU n 1 281 ARG n 1 282 ARG n 1 283 ILE n 1 284 GLN n 1 285 ASN n 1 286 TYR n 1 287 SER n 1 288 VAL n 1 289 MET n 1 290 ASP n 1 291 ILE n 1 292 CYS n 1 293 ASP n 1 294 TYR n 1 295 ASP n 1 296 GLU n 1 297 SER n 1 298 SER n 1 299 GLY n 1 300 ARG n 1 301 TRP n 1 302 ASN n 1 303 CYS n 1 304 LEU n 1 305 VAL n 1 306 ALA n 1 307 ARG n 1 308 GLN n 1 309 HIS n 1 310 ILE n 1 311 GLU n 1 312 MET n 1 313 SER n 1 314 THR n 1 315 THR n 1 316 GLY n 1 317 TRP n 1 318 VAL n 1 319 GLY n 1 320 ARG n 1 321 PHE n 1 322 ARG n 1 323 PRO n 1 324 SER n 1 325 GLU n 1 326 PRO n 1 327 HIS n 1 328 PHE n 1 329 THR n 1 330 LEU n 1 331 ASP n 1 332 GLY n 1 333 ASN n 1 334 SER n 1 335 PHE n 1 336 TYR n 1 337 LYS n 1 338 ILE n 1 339 ILE n 1 340 SER n 1 341 ASN n 1 342 GLU n 1 343 GLU n 1 344 GLY n 1 345 TYR n 1 346 ARG n 1 347 HIS n 1 348 ILE n 1 349 CYS n 1 350 TYR n 1 351 PHE n 1 352 GLN n 1 353 ILE n 1 354 ASP n 1 355 LYS n 1 356 LYS n 1 357 ASP n 1 358 CYS n 1 359 THR n 1 360 PHE n 1 361 ILE n 1 362 THR n 1 363 LYS n 1 364 GLY n 1 365 THR n 1 366 TRP n 1 367 GLU n 1 368 VAL n 1 369 ILE n 1 370 GLY n 1 371 ILE n 1 372 GLU n 1 373 ALA n 1 374 LEU n 1 375 THR n 1 376 SER n 1 377 ASP n 1 378 TYR n 1 379 LEU n 1 380 TYR n 1 381 TYR n 1 382 ILE n 1 383 SER n 1 384 ASN n 1 385 GLU n 1 386 TYR n 1 387 LYS n 1 388 GLY n 1 389 MET n 1 390 PRO n 1 391 GLY n 1 392 GLY n 1 393 ARG n 1 394 ASN n 1 395 LEU n 1 396 TYR n 1 397 LYS n 1 398 ILE n 1 399 GLN n 1 400 LEU n 1 401 SER n 1 402 ASP n 1 403 TYR n 1 404 THR n 1 405 LYS n 1 406 VAL n 1 407 THR n 1 408 CYS n 1 409 LEU n 1 410 SER n 1 411 CYS n 1 412 GLU n 1 413 LEU n 1 414 ASN n 1 415 PRO n 1 416 GLU n 1 417 ARG n 1 418 CYS n 1 419 GLN n 1 420 TYR n 1 421 TYR n 1 422 SER n 1 423 VAL n 1 424 SER n 1 425 PHE n 1 426 SER n 1 427 LYS n 1 428 GLU n 1 429 ALA n 1 430 LYS n 1 431 TYR n 1 432 TYR n 1 433 GLN n 1 434 LEU n 1 435 ARG n 1 436 CYS n 1 437 SER n 1 438 GLY n 1 439 PRO n 1 440 GLY n 1 441 LEU n 1 442 PRO n 1 443 LEU n 1 444 TYR n 1 445 THR n 1 446 LEU n 1 447 HIS n 1 448 SER n 1 449 SER n 1 450 VAL n 1 451 ASN n 1 452 ASP n 1 453 LYS n 1 454 GLY n 1 455 LEU n 1 456 ARG n 1 457 VAL n 1 458 LEU n 1 459 GLU n 1 460 ASP n 1 461 ASN n 1 462 SER n 1 463 ALA n 1 464 LEU n 1 465 ASP n 1 466 LYS n 1 467 MET n 1 468 LEU n 1 469 GLN n 1 470 ASN n 1 471 VAL n 1 472 GLN n 1 473 MET n 1 474 PRO n 1 475 SER n 1 476 LYS n 1 477 LYS n 1 478 LEU n 1 479 ASP n 1 480 PHE n 1 481 ILE n 1 482 ILE n 1 483 LEU n 1 484 ASN n 1 485 GLU n 1 486 THR n 1 487 LYS n 1 488 PHE n 1 489 TRP n 1 490 TYR n 1 491 GLN n 1 492 MET n 1 493 ILE n 1 494 LEU n 1 495 PRO n 1 496 PRO n 1 497 HIS n 1 498 PHE n 1 499 ASP n 1 500 LYS n 1 501 SER n 1 502 LYS n 1 503 LYS n 1 504 TYR n 1 505 PRO n 1 506 LEU n 1 507 LEU n 1 508 LEU n 1 509 ASP n 1 510 VAL n 1 511 TYR n 1 512 ALA n 1 513 GLY n 1 514 PRO n 1 515 CYS n 1 516 SER n 1 517 GLN n 1 518 LYS n 1 519 ALA n 1 520 ASP n 1 521 THR n 1 522 VAL n 1 523 PHE n 1 524 ARG n 1 525 LEU n 1 526 ASN n 1 527 TRP n 1 528 ALA n 1 529 THR n 1 530 TYR n 1 531 LEU n 1 532 ALA n 1 533 SER n 1 534 THR n 1 535 GLU n 1 536 ASN n 1 537 ILE n 1 538 ILE n 1 539 VAL n 1 540 ALA n 1 541 SER n 1 542 PHE n 1 543 ASP n 1 544 GLY n 1 545 ARG n 1 546 GLY n 1 547 SER n 1 548 GLY n 1 549 TYR n 1 550 GLN n 1 551 GLY n 1 552 ASP n 1 553 LYS n 1 554 ILE n 1 555 MET n 1 556 HIS n 1 557 ALA n 1 558 ILE n 1 559 ASN n 1 560 ARG n 1 561 ARG n 1 562 LEU n 1 563 GLY n 1 564 THR n 1 565 PHE n 1 566 GLU n 1 567 VAL n 1 568 GLU n 1 569 ASP n 1 570 GLN n 1 571 ILE n 1 572 GLU n 1 573 ALA n 1 574 ALA n 1 575 ARG n 1 576 GLN n 1 577 PHE n 1 578 SER n 1 579 LYS n 1 580 MET n 1 581 GLY n 1 582 PHE n 1 583 VAL n 1 584 ASP n 1 585 ASN n 1 586 LYS n 1 587 ARG n 1 588 ILE n 1 589 ALA n 1 590 ILE n 1 591 TRP n 1 592 GLY n 1 593 TRP n 1 594 SER n 1 595 TYR n 1 596 GLY n 1 597 GLY n 1 598 TYR n 1 599 VAL n 1 600 THR n 1 601 SER n 1 602 MET n 1 603 VAL n 1 604 LEU n 1 605 GLY n 1 606 SER n 1 607 GLY n 1 608 SER n 1 609 GLY n 1 610 VAL n 1 611 PHE n 1 612 LYS n 1 613 CYS n 1 614 GLY n 1 615 ILE n 1 616 ALA n 1 617 VAL n 1 618 ALA n 1 619 PRO n 1 620 VAL n 1 621 SER n 1 622 ARG n 1 623 TRP n 1 624 GLU n 1 625 TYR n 1 626 TYR n 1 627 ASP n 1 628 SER n 1 629 VAL n 1 630 TYR n 1 631 THR n 1 632 GLU n 1 633 ARG n 1 634 TYR n 1 635 MET n 1 636 GLY n 1 637 LEU n 1 638 PRO n 1 639 THR n 1 640 PRO n 1 641 GLU n 1 642 ASP n 1 643 ASN n 1 644 LEU n 1 645 ASP n 1 646 HIS n 1 647 TYR n 1 648 ARG n 1 649 ASN n 1 650 SER n 1 651 THR n 1 652 VAL n 1 653 MET n 1 654 SER n 1 655 ARG n 1 656 ALA n 1 657 GLU n 1 658 ASN n 1 659 PHE n 1 660 LYS n 1 661 GLN n 1 662 VAL n 1 663 GLU n 1 664 TYR n 1 665 LEU n 1 666 LEU n 1 667 ILE n 1 668 HIS n 1 669 GLY n 1 670 THR n 1 671 ALA n 1 672 ASP n 1 673 ASP n 1 674 ASN n 1 675 VAL n 1 676 HIS n 1 677 PHE n 1 678 GLN n 1 679 GLN n 1 680 SER n 1 681 ALA n 1 682 GLN n 1 683 ILE n 1 684 SER n 1 685 LYS n 1 686 ALA n 1 687 LEU n 1 688 VAL n 1 689 ASP n 1 690 VAL n 1 691 GLY n 1 692 VAL n 1 693 ASP n 1 694 PHE n 1 695 GLN n 1 696 ALA n 1 697 MET n 1 698 TRP n 1 699 TYR n 1 700 THR n 1 701 ASP n 1 702 GLU n 1 703 ASP n 1 704 HIS n 1 705 GLY n 1 706 ILE n 1 707 ALA n 1 708 SER n 1 709 SER n 1 710 THR n 1 711 ALA n 1 712 HIS n 1 713 GLN n 1 714 HIS n 1 715 ILE n 1 716 TYR n 1 717 THR n 1 718 HIS n 1 719 MET n 1 720 SER n 1 721 HIS n 1 722 PHE n 1 723 ILE n 1 724 LYS n 1 725 GLN n 1 726 CYS n 1 727 PHE n 1 728 SER n 1 729 LEU n 1 730 PRO n 1 731 PRO n 1 732 LEU n 1 733 GLU n 1 734 GLN n 1 735 LYS n 1 736 LEU n 1 737 ILE n 1 738 SER n 1 739 GLU n 1 740 GLU n 1 741 ASP n 1 742 LEU n 1 743 ASN n 1 744 SER n 1 745 ALA n 1 746 VAL n 1 747 ASP n 1 748 HIS n 1 749 HIS n 1 750 HIS n 1 751 HIS n 1 752 HIS n 1 753 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'DPP4, ADCP2, CD26' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Pichia pastoris' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 4922 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type PLASMID _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pPICZalpha _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code DPP4_HUMAN _struct_ref.pdbx_db_accession P27487 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEY NYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGI TDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSS VTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFR PSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSD YTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFII LNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRL GTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED NLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHF IKQCFSLP ; _struct_ref.pdbx_align_begin 39 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3SWW A 3 ? 730 ? P27487 39 ? 766 ? 39 766 2 1 3SWW B 3 ? 730 ? P27487 39 ? 766 ? 39 766 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3SWW GLU A 1 ? UNP P27487 ? ? 'EXPRESSION TAG' 37 1 1 3SWW PHE A 2 ? UNP P27487 ? ? 'EXPRESSION TAG' 38 2 1 3SWW PRO A 731 ? UNP P27487 ? ? 'EXPRESSION TAG' 767 3 1 3SWW LEU A 732 ? UNP P27487 ? ? 'EXPRESSION TAG' 768 4 1 3SWW GLU A 733 ? UNP P27487 ? ? 'EXPRESSION TAG' 769 5 1 3SWW GLN A 734 ? UNP P27487 ? ? 'EXPRESSION TAG' 770 6 1 3SWW LYS A 735 ? UNP P27487 ? ? 'EXPRESSION TAG' 771 7 1 3SWW LEU A 736 ? UNP P27487 ? ? 'EXPRESSION TAG' 772 8 1 3SWW ILE A 737 ? UNP P27487 ? ? 'EXPRESSION TAG' 773 9 1 3SWW SER A 738 ? UNP P27487 ? ? 'EXPRESSION TAG' 774 10 1 3SWW GLU A 739 ? UNP P27487 ? ? 'EXPRESSION TAG' 775 11 1 3SWW GLU A 740 ? UNP P27487 ? ? 'EXPRESSION TAG' 776 12 1 3SWW ASP A 741 ? UNP P27487 ? ? 'EXPRESSION TAG' 777 13 1 3SWW LEU A 742 ? UNP P27487 ? ? 'EXPRESSION TAG' 778 14 1 3SWW ASN A 743 ? UNP P27487 ? ? 'EXPRESSION TAG' 779 15 1 3SWW SER A 744 ? UNP P27487 ? ? 'EXPRESSION TAG' 780 16 1 3SWW ALA A 745 ? UNP P27487 ? ? 'EXPRESSION TAG' 781 17 1 3SWW VAL A 746 ? UNP P27487 ? ? 'EXPRESSION TAG' 782 18 1 3SWW ASP A 747 ? UNP P27487 ? ? 'EXPRESSION TAG' 783 19 1 3SWW HIS A 748 ? UNP P27487 ? ? 'EXPRESSION TAG' 784 20 1 3SWW HIS A 749 ? UNP P27487 ? ? 'EXPRESSION TAG' 785 21 1 3SWW HIS A 750 ? UNP P27487 ? ? 'EXPRESSION TAG' 786 22 1 3SWW HIS A 751 ? UNP P27487 ? ? 'EXPRESSION TAG' 787 23 1 3SWW HIS A 752 ? UNP P27487 ? ? 'EXPRESSION TAG' 788 24 1 3SWW HIS A 753 ? UNP P27487 ? ? 'EXPRESSION TAG' 789 25 2 3SWW GLU B 1 ? UNP P27487 ? ? 'EXPRESSION TAG' 37 26 2 3SWW PHE B 2 ? UNP P27487 ? ? 'EXPRESSION TAG' 38 27 2 3SWW PRO B 731 ? UNP P27487 ? ? 'EXPRESSION TAG' 767 28 2 3SWW LEU B 732 ? UNP P27487 ? ? 'EXPRESSION TAG' 768 29 2 3SWW GLU B 733 ? UNP P27487 ? ? 'EXPRESSION TAG' 769 30 2 3SWW GLN B 734 ? UNP P27487 ? ? 'EXPRESSION TAG' 770 31 2 3SWW LYS B 735 ? UNP P27487 ? ? 'EXPRESSION TAG' 771 32 2 3SWW LEU B 736 ? UNP P27487 ? ? 'EXPRESSION TAG' 772 33 2 3SWW ILE B 737 ? UNP P27487 ? ? 'EXPRESSION TAG' 773 34 2 3SWW SER B 738 ? UNP P27487 ? ? 'EXPRESSION TAG' 774 35 2 3SWW GLU B 739 ? UNP P27487 ? ? 'EXPRESSION TAG' 775 36 2 3SWW GLU B 740 ? UNP P27487 ? ? 'EXPRESSION TAG' 776 37 2 3SWW ASP B 741 ? UNP P27487 ? ? 'EXPRESSION TAG' 777 38 2 3SWW LEU B 742 ? UNP P27487 ? ? 'EXPRESSION TAG' 778 39 2 3SWW ASN B 743 ? UNP P27487 ? ? 'EXPRESSION TAG' 779 40 2 3SWW SER B 744 ? UNP P27487 ? ? 'EXPRESSION TAG' 780 41 2 3SWW ALA B 745 ? UNP P27487 ? ? 'EXPRESSION TAG' 781 42 2 3SWW VAL B 746 ? UNP P27487 ? ? 'EXPRESSION TAG' 782 43 2 3SWW ASP B 747 ? UNP P27487 ? ? 'EXPRESSION TAG' 783 44 2 3SWW HIS B 748 ? UNP P27487 ? ? 'EXPRESSION TAG' 784 45 2 3SWW HIS B 749 ? UNP P27487 ? ? 'EXPRESSION TAG' 785 46 2 3SWW HIS B 750 ? UNP P27487 ? ? 'EXPRESSION TAG' 786 47 2 3SWW HIS B 751 ? UNP P27487 ? ? 'EXPRESSION TAG' 787 48 2 3SWW HIS B 752 ? UNP P27487 ? ? 'EXPRESSION TAG' 788 49 2 3SWW HIS B 753 ? UNP P27487 ? ? 'EXPRESSION TAG' 789 50 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 KXB non-polymer . '3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyethyl)-2-methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one' ? 'C18 H19 Cl2 N3 O2' 380.268 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.crystals_number 1 _exptl.entry_id 3SWW _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 2.69 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 54.35 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 8.5 _exptl_crystal_grow.temp 298 _exptl_crystal_grow.pdbx_details ;CRYSTALS GROWN IN 2 UL EQUIVOLUME MIXTURE OF PROTEIN SOLUTION (0.1 M NACL, 20 MM TRIS-HCL BUFFER PH 7.8, 9.8 MG/ML PROTEIN) AND CRYSTALLIZATION SOLUTION (17% W/V PEG 3350, 15% W/V GLYCEROL, 200 MM MGCL2, 100 MM TRIS-HCL). SUFFICIENT 100 MM LIGAND STOCK SOLUTION (NEAT DMSO) ADDED TO ACHIEVE 1 MM LIGAND CONCENTRATION. SOAKED OVERNIGHT. HARVESTED DIRECTLY AND CRYO-STORED IN LN2 VAPOR DIFFUSION / HANGING DROP, temperature 298K ; _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100.0 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC Q315' _diffrn_detector.pdbx_collection_date 2005-06-08 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'NSLS BEAMLINE X29A' _diffrn_source.pdbx_wavelength_list ? _diffrn_source.pdbx_synchrotron_site NSLS _diffrn_source.pdbx_synchrotron_beamline X29A _diffrn_source.pdbx_wavelength 1.0 # _reflns.entry_id 3SWW _reflns.d_resolution_high 2.000 _reflns.d_resolution_low 50.000 _reflns.number_obs 110050 _reflns.pdbx_Rmerge_I_obs 0.113 _reflns.pdbx_netI_over_sigmaI 22.900 _reflns.pdbx_redundancy 6.700 _reflns.percent_possible_obs 84.900 _reflns.B_iso_Wilson_estimate 32.800 _reflns.observed_criterion_sigma_I 0.000 _reflns.observed_criterion_sigma_F ? _reflns.number_all ? _reflns.pdbx_Rsym_value ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1,1 # _reflns_shell.d_res_high 2.000 _reflns_shell.d_res_low 2.070 _reflns_shell.number_measured_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_unique_obs ? _reflns_shell.Rmerge_I_obs 0.323 _reflns_shell.meanI_over_sigI_obs 3.100 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_redundancy 2.700 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.percent_possible_all 40.800 _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1,1 # _refine.entry_id 3SWW _refine.ls_d_res_high 2.00 _refine.ls_d_res_low 47.1630 _refine.pdbx_ls_sigma_F 1.450 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_percent_reflns_obs 84.8000 _refine.ls_number_reflns_obs 109947 _refine.ls_number_reflns_all ? _refine.pdbx_ls_cross_valid_method ? _refine.pdbx_R_Free_selection_details ? _refine.details ? _refine.ls_R_factor_all ? _refine.ls_R_factor_obs 0.1985 _refine.ls_R_factor_R_work 0.1966 _refine.ls_wR_factor_R_work ? _refine.ls_R_factor_R_free 0.2342 _refine.ls_wR_factor_R_free ? _refine.ls_percent_reflns_R_free 5.0400 _refine.ls_number_reflns_R_free 5540 _refine.ls_R_factor_R_free_error ? _refine.B_iso_mean 36.2037 _refine.solvent_model_param_bsol 28.3980 _refine.solvent_model_param_ksol 0.3390 _refine.pdbx_isotropic_thermal_model ? _refine.aniso_B[1][1] 3.9664 _refine.aniso_B[2][2] 4.3715 _refine.aniso_B[3][3] -8.3379 _refine.aniso_B[1][2] 0.0000 _refine.aniso_B[1][3] -0.0000 _refine.aniso_B[2][3] -0.0000 _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML 0.3000 _refine.overall_SU_B ? _refine.solvent_model_details 'FLAT BULK SOLVENT MODEL' _refine.pdbx_solvent_vdw_probe_radii 1.1100 _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii 0.9000 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.pdbx_starting_model 3NOX.PDB _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values ML _refine.pdbx_stereochem_target_val_spec_case ? _refine.overall_FOM_work_R_set ? _refine.B_iso_max 87.150 _refine.B_iso_min 17.120 _refine.pdbx_overall_phase_error 25.8500 _refine.occupancy_max 1.000 _refine.occupancy_min 1.000 _refine.pdbx_ls_sigma_I ? _refine.ls_redundancy_reflns_obs ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.overall_FOM_free_R_set ? _refine.pdbx_diffrn_id 1,1 _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_ESU_R ? _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 11788 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 246 _refine_hist.number_atoms_solvent 431 _refine_hist.number_atoms_total 12465 _refine_hist.d_res_high 2.00 _refine_hist.d_res_low 47.1630 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_restraint_function _refine_ls_restr.pdbx_refine_id f_bond_d 12405 0.007 ? ? ? 'X-RAY DIFFRACTION' f_angle_d 16897 1.090 ? ? ? 'X-RAY DIFFRACTION' f_chiral_restr 1811 0.079 ? ? ? 'X-RAY DIFFRACTION' f_plane_restr 2126 0.004 ? ? ? 'X-RAY DIFFRACTION' f_dihedral_angle_d 4443 15.579 ? ? ? 'X-RAY DIFFRACTION' # loop_ _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.percent_reflns_obs _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_R_work _refine_ls_shell.R_factor_R_free _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.pdbx_refine_id 1.9979 2.0206 30 35.0000 1385 . 0.2167 0.2823 . 75 . 1460 . . 'X-RAY DIFFRACTION' 2.0206 2.0443 30 41.0000 1685 . 0.2250 0.2644 . 69 . 1754 . . 'X-RAY DIFFRACTION' 2.0443 2.0693 30 45.0000 1827 . 0.2269 0.2926 . 74 . 1901 . . 'X-RAY DIFFRACTION' 2.0693 2.0955 30 50.0000 1997 . 0.2336 0.2887 . 122 . 2119 . . 'X-RAY DIFFRACTION' 2.0955 2.1230 30 55.0000 2233 . 0.2252 0.2827 . 110 . 2343 . . 'X-RAY DIFFRACTION' 2.1230 2.1521 30 61.0000 2424 . 0.2244 0.2873 . 140 . 2564 . . 'X-RAY DIFFRACTION' 2.1521 2.1829 30 63.0000 2612 . 0.2140 0.2340 . 130 . 2742 . . 'X-RAY DIFFRACTION' 2.1829 2.2154 30 70.0000 2785 . 0.2151 0.2559 . 152 . 2937 . . 'X-RAY DIFFRACTION' 2.2154 2.2501 30 72.0000 2982 . 0.2245 0.3144 . 144 . 3126 . . 'X-RAY DIFFRACTION' 2.2501 2.2869 30 79.0000 3161 . 0.2191 0.2638 . 159 . 3320 . . 'X-RAY DIFFRACTION' 2.2869 2.3264 30 84.0000 3435 . 0.2163 0.2841 . 175 . 3610 . . 'X-RAY DIFFRACTION' 2.3264 2.3687 30 90.0000 3704 . 0.2255 0.2689 . 155 . 3859 . . 'X-RAY DIFFRACTION' 2.3687 2.4142 30 97.0000 3993 . 0.2292 0.2695 . 197 . 4190 . . 'X-RAY DIFFRACTION' 2.4142 2.4635 30 99.0000 3981 . 0.2351 0.2397 . 232 . 4213 . . 'X-RAY DIFFRACTION' 2.4635 2.5171 30 100.0000 4077 . 0.2347 0.2918 . 252 . 4329 . . 'X-RAY DIFFRACTION' 2.5171 2.5756 30 100.0000 4012 . 0.2205 0.2773 . 223 . 4235 . . 'X-RAY DIFFRACTION' 2.5756 2.6400 30 100.0000 4126 . 0.2352 0.2863 . 220 . 4346 . . 'X-RAY DIFFRACTION' 2.6400 2.7114 30 100.0000 4076 . 0.2259 0.2641 . 232 . 4308 . . 'X-RAY DIFFRACTION' 2.7114 2.7912 30 100.0000 4058 . 0.2324 0.2465 . 224 . 4282 . . 'X-RAY DIFFRACTION' 2.7912 2.8813 30 100.0000 4072 . 0.2274 0.2742 . 250 . 4322 . . 'X-RAY DIFFRACTION' 2.8813 2.9842 30 100.0000 4104 . 0.2259 0.2643 . 222 . 4326 . . 'X-RAY DIFFRACTION' 2.9842 3.1037 30 100.0000 4089 . 0.2207 0.2666 . 234 . 4323 . . 'X-RAY DIFFRACTION' 3.1037 3.2449 30 100.0000 4132 . 0.2099 0.2513 . 213 . 4345 . . 'X-RAY DIFFRACTION' 3.2449 3.4159 30 100.0000 4126 . 0.2051 0.2345 . 210 . 4336 . . 'X-RAY DIFFRACTION' 3.4159 3.6299 30 100.0000 4152 . 0.1981 0.2356 . 214 . 4366 . . 'X-RAY DIFFRACTION' 3.6299 3.9100 30 100.0000 4124 . 0.1801 0.2170 . 218 . 4342 . . 'X-RAY DIFFRACTION' 3.9100 4.3033 30 100.0000 4207 . 0.1554 0.2024 . 202 . 4409 . . 'X-RAY DIFFRACTION' 4.3033 4.9254 30 100.0000 4170 . 0.1347 0.1518 . 234 . 4404 . . 'X-RAY DIFFRACTION' 4.9254 6.2032 30 100.0000 4244 . 0.1700 0.2273 . 234 . 4478 . . 'X-RAY DIFFRACTION' 6.2032 47.1763 30 99.0000 4434 . 0.1960 0.2067 . 224 . 4658 . . 'X-RAY DIFFRACTION' # _struct.entry_id 3SWW _struct.title ;Crystal structure of human dpp-iv in complex with sa-(+)-3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyphenyl)- 2-methyl-5h-pyrrolo[3,4-b]pyridin-7(6h)-one ; _struct.pdbx_descriptor 'Dipeptidyl peptidase 4 (E.C.3.4.14.5)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3SWW _struct_keywords.text ;EXOPEPTIDASE, ALPHA/BETA HYDROLASE FOLD, BETA BARREL, BETA PROPELLER, DPP4, DIMER, PROTEIN:INHIBITOR COMPLEX, AMINOPEPTIDASE, GLYCOPROTEIN, MEMBRANE, PROTEASE, SECRETED, SERINE PROTEASE, SIGNAL-ANCHOR, TRANSMEMBRANE, HYDROLASE-HYDROLASE inhibitor complex ; _struct_keywords.pdbx_keywords 'HYDROLASE/HYDROLASE inhibitor' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 2 ? J N N 3 ? K N N 2 ? L N N 2 ? M N N 2 ? N N N 2 ? O N N 2 ? P N N 2 ? Q N N 2 ? R N N 3 ? S N N 4 ? T N N 4 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 THR A 8 ? ASN A 15 ? THR A 44 ASN A 51 1 ? 8 HELX_P HELX_P2 2 ASP A 164 ? VAL A 171 ? ASP A 200 VAL A 207 1 ? 8 HELX_P HELX_P3 3 PRO A 254 ? ILE A 259 ? PRO A 290 ILE A 295 1 ? 6 HELX_P HELX_P4 4 LEU A 304 ? GLN A 308 ? LEU A 340 GLN A 344 5 ? 5 HELX_P HELX_P5 5 GLU A 385 ? MET A 389 ? GLU A 421 MET A 425 5 ? 5 HELX_P HELX_P6 6 LYS A 427 ? ALA A 429 ? LYS A 463 ALA A 465 5 ? 3 HELX_P HELX_P7 7 ASN A 461 ? GLN A 469 ? ASN A 497 GLN A 505 1 ? 9 HELX_P HELX_P8 8 ASN A 526 ? THR A 534 ? ASN A 562 THR A 570 1 ? 9 HELX_P HELX_P9 9 GLY A 551 ? HIS A 556 ? GLY A 587 HIS A 592 1 ? 6 HELX_P HELX_P10 10 ALA A 557 ? ASN A 559 ? ALA A 593 ASN A 595 5 ? 3 HELX_P HELX_P11 11 THR A 564 ? MET A 580 ? THR A 600 MET A 616 1 ? 17 HELX_P HELX_P12 12 SER A 594 ? GLY A 605 ? SER A 630 GLY A 641 1 ? 12 HELX_P HELX_P13 13 ARG A 622 ? TYR A 626 ? ARG A 658 TYR A 662 5 ? 5 HELX_P HELX_P14 14 ASP A 627 ? GLY A 636 ? ASP A 663 GLY A 672 1 ? 10 HELX_P HELX_P15 15 ASN A 643 ? SER A 650 ? ASN A 679 SER A 686 1 ? 8 HELX_P HELX_P16 16 VAL A 652 ? VAL A 662 ? VAL A 688 VAL A 698 5 ? 11 HELX_P HELX_P17 17 HIS A 676 ? VAL A 690 ? HIS A 712 VAL A 726 1 ? 15 HELX_P HELX_P18 18 SER A 708 ? PHE A 727 ? SER A 744 PHE A 763 1 ? 20 HELX_P HELX_P19 19 THR B 8 ? ASN B 15 ? THR B 44 ASN B 51 1 ? 8 HELX_P HELX_P20 20 ASP B 164 ? VAL B 171 ? ASP B 200 VAL B 207 1 ? 8 HELX_P HELX_P21 21 ASP B 238 ? LEU B 240 ? ASP B 274 LEU B 276 5 ? 3 HELX_P HELX_P22 22 PRO B 254 ? ILE B 259 ? PRO B 290 ILE B 295 1 ? 6 HELX_P HELX_P23 23 LEU B 304 ? GLN B 308 ? LEU B 340 GLN B 344 5 ? 5 HELX_P HELX_P24 24 GLU B 385 ? MET B 389 ? GLU B 421 MET B 425 5 ? 5 HELX_P HELX_P25 25 LYS B 427 ? ALA B 429 ? LYS B 463 ALA B 465 5 ? 3 HELX_P HELX_P26 26 ASN B 461 ? GLN B 469 ? ASN B 497 GLN B 505 1 ? 9 HELX_P HELX_P27 27 ASN B 526 ? ASN B 536 ? ASN B 562 ASN B 572 1 ? 11 HELX_P HELX_P28 28 GLY B 551 ? HIS B 556 ? GLY B 587 HIS B 592 1 ? 6 HELX_P HELX_P29 29 ALA B 557 ? ASN B 559 ? ALA B 593 ASN B 595 5 ? 3 HELX_P HELX_P30 30 THR B 564 ? MET B 580 ? THR B 600 MET B 616 1 ? 17 HELX_P HELX_P31 31 SER B 594 ? GLY B 605 ? SER B 630 GLY B 641 1 ? 12 HELX_P HELX_P32 32 ARG B 622 ? TYR B 626 ? ARG B 658 TYR B 662 5 ? 5 HELX_P HELX_P33 33 ASP B 627 ? GLY B 636 ? ASP B 663 GLY B 672 1 ? 10 HELX_P HELX_P34 34 ASN B 643 ? SER B 650 ? ASN B 679 SER B 686 1 ? 8 HELX_P HELX_P35 35 VAL B 652 ? VAL B 662 ? VAL B 688 VAL B 698 5 ? 11 HELX_P HELX_P36 36 HIS B 676 ? VAL B 690 ? HIS B 712 VAL B 726 1 ? 15 HELX_P HELX_P37 37 SER B 708 ? PHE B 727 ? SER B 744 PHE B 763 1 ? 20 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 292 SG ? ? ? 1_555 A CYS 303 SG ? ? A CYS 328 A CYS 339 1_555 ? ? ? ? ? ? ? 2.055 ? disulf2 disulf ? ? A CYS 349 SG ? ? ? 1_555 A CYS 358 SG ? ? A CYS 385 A CYS 394 1_555 ? ? ? ? ? ? ? 2.046 ? disulf3 disulf ? ? A CYS 408 SG ? ? ? 1_555 A CYS 411 SG ? ? A CYS 444 A CYS 447 1_555 ? ? ? ? ? ? ? 2.039 ? disulf4 disulf ? ? A CYS 418 SG ? ? ? 1_555 A CYS 436 SG ? ? A CYS 454 A CYS 472 1_555 ? ? ? ? ? ? ? 2.086 ? disulf5 disulf ? ? A CYS 613 SG ? ? ? 1_555 A CYS 726 SG ? ? A CYS 649 A CYS 762 1_555 ? ? ? ? ? ? ? 2.062 ? disulf6 disulf ? ? B CYS 292 SG ? ? ? 1_555 B CYS 303 SG ? ? B CYS 328 B CYS 339 1_555 ? ? ? ? ? ? ? 2.054 ? disulf7 disulf ? ? B CYS 349 SG ? ? ? 1_555 B CYS 358 SG ? ? B CYS 385 B CYS 394 1_555 ? ? ? ? ? ? ? 2.039 ? disulf8 disulf ? ? B CYS 408 SG ? ? ? 1_555 B CYS 411 SG ? ? B CYS 444 B CYS 447 1_555 ? ? ? ? ? ? ? 2.037 ? disulf9 disulf ? ? B CYS 418 SG ? ? ? 1_555 B CYS 436 SG ? ? B CYS 454 B CYS 472 1_555 ? ? ? ? ? ? ? 2.096 ? disulf10 disulf ? ? B CYS 613 SG ? ? ? 1_555 B CYS 726 SG ? ? B CYS 649 B CYS 762 1_555 ? ? ? ? ? ? ? 2.054 ? covale1 covale ? ? B ASN 484 ND2 ? ? ? 1_555 Q NAG . C1 ? ? B ASN 520 B NAG 5201 1_555 ? ? ? ? ? ? ? 1.428 ? covale2 covale ? ? A ASN 114 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 150 A NAG 1501 1_555 ? ? ? ? ? ? ? 1.433 ? covale3 covale ? ? B ASN 114 ND2 ? ? ? 1_555 M NAG . C1 ? ? B ASN 150 B NAG 1501 1_555 ? ? ? ? ? ? ? 1.434 ? covale4 covale ? ? B ASN 49 ND2 ? ? ? 1_555 K NAG . C1 ? ? B ASN 85 B NAG 851 1_555 ? ? ? ? ? ? ? 1.434 ? covale5 covale ? ? A ASN 49 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 85 A NAG 851 1_555 ? ? ? ? ? ? ? 1.435 ? covale6 covale ? ? B ASN 183 ND2 ? ? ? 1_555 N NAG . C1 ? ? B ASN 219 B NAG 2191 1_555 ? ? ? ? ? ? ? 1.437 ? covale7 covale ? ? B ASN 193 ND2 ? ? ? 1_555 O NAG . C1 ? ? B ASN 229 B NAG 2291 1_555 ? ? ? ? ? ? ? 1.439 ? covale8 covale ? ? A ASN 484 ND2 ? ? ? 1_555 I NAG . C1 ? ? A ASN 520 A NAG 5201 1_555 ? ? ? ? ? ? ? 1.440 ? covale9 covale ? ? A ASN 183 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 219 A NAG 2191 1_555 ? ? ? ? ? ? ? 1.442 ? covale10 covale ? ? B ASN 56 ND2 ? ? ? 1_555 L NAG . C1 ? ? B ASN 92 B NAG 921 1_555 ? ? ? ? ? ? ? 1.443 ? covale11 covale ? ? A ASN 193 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 229 A NAG 2291 1_555 ? ? ? ? ? ? ? 1.445 ? covale12 covale ? ? F NAG . O4 ? ? ? 1_555 G NAG . C1 ? ? A NAG 2291 A NAG 2292 1_555 ? ? ? ? ? ? ? 1.447 ? covale13 covale ? ? O NAG . O4 ? ? ? 1_555 P NAG . C1 ? ? B NAG 2291 B NAG 2292 1_555 ? ? ? ? ? ? ? 1.451 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLY 438 A . ? GLY 474 A PRO 439 A ? PRO 475 A 1 11.07 2 GLY 438 B . ? GLY 474 B PRO 439 B ? PRO 475 B 1 5.45 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 4 ? C ? 4 ? D ? 4 ? E ? 3 ? F ? 4 ? G ? 2 ? H ? 4 ? I ? 4 ? J ? 4 ? K ? 4 ? L ? 4 ? M ? 8 ? N ? 2 ? O ? 4 ? P ? 4 ? Q ? 4 ? R ? 3 ? S ? 4 ? T ? 2 ? U ? 4 ? V ? 4 ? W ? 4 ? X ? 4 ? Y ? 4 ? Z ? 8 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel L 1 2 ? anti-parallel L 2 3 ? anti-parallel L 3 4 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel M 3 4 ? parallel M 4 5 ? parallel M 5 6 ? parallel M 6 7 ? parallel M 7 8 ? parallel N 1 2 ? parallel O 1 2 ? anti-parallel O 2 3 ? anti-parallel O 3 4 ? anti-parallel P 1 2 ? anti-parallel P 2 3 ? anti-parallel P 3 4 ? anti-parallel Q 1 2 ? anti-parallel Q 2 3 ? anti-parallel Q 3 4 ? anti-parallel R 1 2 ? anti-parallel R 2 3 ? anti-parallel S 1 2 ? anti-parallel S 2 3 ? anti-parallel S 3 4 ? anti-parallel T 1 2 ? anti-parallel U 1 2 ? anti-parallel U 2 3 ? anti-parallel U 3 4 ? anti-parallel V 1 2 ? anti-parallel V 2 3 ? anti-parallel V 3 4 ? anti-parallel W 1 2 ? anti-parallel W 2 3 ? anti-parallel W 3 4 ? anti-parallel X 1 2 ? anti-parallel X 2 3 ? anti-parallel X 3 4 ? anti-parallel Y 1 2 ? anti-parallel Y 2 3 ? anti-parallel Y 3 4 ? anti-parallel Z 1 2 ? anti-parallel Z 2 3 ? anti-parallel Z 3 4 ? parallel Z 4 5 ? parallel Z 5 6 ? parallel Z 6 7 ? parallel Z 7 8 ? parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 LYS A 5 ? THR A 6 ? LYS A 41 THR A 42 A 2 VAL A 471 ? GLN A 472 ? VAL A 507 GLN A 508 B 1 ARG A 25 ? TRP A 26 ? ARG A 61 TRP A 62 B 2 GLU A 31 ? GLN A 36 ? GLU A 67 GLN A 72 B 3 ASN A 39 ? ASN A 44 ? ASN A 75 ASN A 80 B 4 SER A 50 ? LEU A 54 ? SER A 86 LEU A 90 C 1 ILE A 66 ? ILE A 71 ? ILE A 102 ILE A 107 C 2 PHE A 77 ? LYS A 86 ? PHE A 113 LYS A 122 C 3 TYR A 92 ? ASP A 100 ? TYR A 128 ASP A 136 C 4 GLN A 105 ? LEU A 106 ? GLN A 141 LEU A 142 D 1 TRP A 118 ? TRP A 121 ? TRP A 154 TRP A 157 D 2 LEU A 128 ? TRP A 132 ? LEU A 164 TRP A 168 D 3 ASP A 135 ? LYS A 139 ? ASP A 171 LYS A 175 D 4 TYR A 147 ? ARG A 148 ? TYR A 183 ARG A 184 E 1 ILE A 158 ? ASN A 160 ? ILE A 194 ASN A 196 E 2 PHE A 186 ? ASN A 193 ? PHE A 222 ASN A 229 E 3 LEU A 178 ? TRP A 180 ? LEU A 214 TRP A 216 F 1 ILE A 158 ? ASN A 160 ? ILE A 194 ASN A 196 F 2 PHE A 186 ? ASN A 193 ? PHE A 222 ASN A 229 F 3 THR A 229 ? ASN A 236 ? THR A 265 ASN A 272 F 4 SER A 248 ? ILE A 251 ? SER A 284 ILE A 287 G 1 LEU A 199 ? PHE A 204 ? LEU A 235 PHE A 240 G 2 LYS A 214 ? PRO A 219 ? LYS A 250 PRO A 255 H 1 HIS A 262 ? TRP A 269 ? HIS A 298 TRP A 305 H 2 ARG A 274 ? ARG A 281 ? ARG A 310 ARG A 317 H 3 TYR A 286 ? TYR A 294 ? TYR A 322 TYR A 330 H 4 TRP A 301 ? ASN A 302 ? TRP A 337 ASN A 338 I 1 HIS A 262 ? TRP A 269 ? HIS A 298 TRP A 305 I 2 ARG A 274 ? ARG A 281 ? ARG A 310 ARG A 317 I 3 TYR A 286 ? TYR A 294 ? TYR A 322 TYR A 330 I 4 HIS A 309 ? MET A 312 ? HIS A 345 MET A 348 J 1 HIS A 327 ? PHE A 328 ? HIS A 363 PHE A 364 J 2 SER A 334 ? SER A 340 ? SER A 370 SER A 376 J 3 ARG A 346 ? GLN A 352 ? ARG A 382 GLN A 388 J 4 THR A 359 ? PHE A 360 ? THR A 395 PHE A 396 K 1 VAL A 368 ? LEU A 374 ? VAL A 404 LEU A 410 K 2 TYR A 378 ? SER A 383 ? TYR A 414 SER A 419 K 3 ASN A 394 ? GLN A 399 ? ASN A 430 GLN A 435 K 4 VAL A 406 ? CYS A 408 ? VAL A 442 CYS A 444 L 1 TYR A 421 ? PHE A 425 ? TYR A 457 PHE A 461 L 2 TYR A 431 ? CYS A 436 ? TYR A 467 CYS A 472 L 3 LEU A 443 ? SER A 448 ? LEU A 479 SER A 484 L 4 LYS A 453 ? GLU A 459 ? LYS A 489 GLU A 495 M 1 SER A 475 ? LEU A 483 ? SER A 511 LEU A 519 M 2 THR A 486 ? LEU A 494 ? THR A 522 LEU A 530 M 3 ILE A 538 ? PHE A 542 ? ILE A 574 PHE A 578 M 4 TYR A 504 ? VAL A 510 ? TYR A 540 VAL A 546 M 5 VAL A 583 ? TRP A 593 ? VAL A 619 TRP A 629 M 6 CYS A 613 ? VAL A 617 ? CYS A 649 VAL A 653 M 7 GLU A 663 ? GLY A 669 ? GLU A 699 GLY A 705 M 8 GLN A 695 ? TYR A 699 ? GLN A 731 TYR A 735 N 1 LYS B 5 ? THR B 6 ? LYS B 41 THR B 42 N 2 VAL B 471 ? GLN B 472 ? VAL B 507 GLN B 508 O 1 LEU B 24 ? TRP B 26 ? LEU B 60 TRP B 62 O 2 GLU B 31 ? GLN B 36 ? GLU B 67 GLN B 72 O 3 ASN B 39 ? ASN B 44 ? ASN B 75 ASN B 80 O 4 SER B 50 ? LEU B 54 ? SER B 86 LEU B 90 P 1 ASP B 68 ? ILE B 71 ? ASP B 104 ILE B 107 P 2 PHE B 77 ? LYS B 86 ? PHE B 113 LYS B 122 P 3 TYR B 92 ? ASP B 100 ? TYR B 128 ASP B 136 P 4 GLN B 105 ? LEU B 106 ? GLN B 141 LEU B 142 Q 1 TRP B 118 ? TRP B 121 ? TRP B 154 TRP B 157 Q 2 LEU B 128 ? TRP B 132 ? LEU B 164 TRP B 168 Q 3 ASP B 135 ? LYS B 139 ? ASP B 171 LYS B 175 Q 4 TYR B 147 ? ARG B 148 ? TYR B 183 ARG B 184 R 1 ILE B 158 ? ASN B 160 ? ILE B 194 ASN B 196 R 2 PHE B 186 ? ASN B 193 ? PHE B 222 ASN B 229 R 3 LEU B 178 ? TRP B 180 ? LEU B 214 TRP B 216 S 1 ILE B 158 ? ASN B 160 ? ILE B 194 ASN B 196 S 2 PHE B 186 ? ASN B 193 ? PHE B 222 ASN B 229 S 3 THR B 229 ? ASN B 236 ? THR B 265 ASN B 272 S 4 SER B 248 ? ILE B 251 ? SER B 284 ILE B 287 T 1 LEU B 199 ? PHE B 204 ? LEU B 235 PHE B 240 T 2 LYS B 214 ? PRO B 219 ? LYS B 250 PRO B 255 U 1 HIS B 262 ? THR B 271 ? HIS B 298 THR B 307 U 2 ARG B 274 ? ARG B 281 ? ARG B 310 ARG B 317 U 3 TYR B 286 ? TYR B 294 ? TYR B 322 TYR B 330 U 4 TRP B 301 ? ASN B 302 ? TRP B 337 ASN B 338 V 1 HIS B 262 ? THR B 271 ? HIS B 298 THR B 307 V 2 ARG B 274 ? ARG B 281 ? ARG B 310 ARG B 317 V 3 TYR B 286 ? TYR B 294 ? TYR B 322 TYR B 330 V 4 HIS B 309 ? MET B 312 ? HIS B 345 MET B 348 W 1 HIS B 327 ? PHE B 328 ? HIS B 363 PHE B 364 W 2 SER B 334 ? SER B 340 ? SER B 370 SER B 376 W 3 ARG B 346 ? GLN B 352 ? ARG B 382 GLN B 388 W 4 THR B 359 ? PHE B 360 ? THR B 395 PHE B 396 X 1 VAL B 368 ? LEU B 374 ? VAL B 404 LEU B 410 X 2 TYR B 378 ? SER B 383 ? TYR B 414 SER B 419 X 3 ASN B 394 ? GLN B 399 ? ASN B 430 GLN B 435 X 4 VAL B 406 ? CYS B 408 ? VAL B 442 CYS B 444 Y 1 TYR B 421 ? PHE B 425 ? TYR B 457 PHE B 461 Y 2 TYR B 431 ? CYS B 436 ? TYR B 467 CYS B 472 Y 3 LEU B 443 ? SER B 448 ? LEU B 479 SER B 484 Y 4 LYS B 453 ? GLU B 459 ? LYS B 489 GLU B 495 Z 1 SER B 475 ? LEU B 483 ? SER B 511 LEU B 519 Z 2 THR B 486 ? LEU B 494 ? THR B 522 LEU B 530 Z 3 ILE B 538 ? PHE B 542 ? ILE B 574 PHE B 578 Z 4 TYR B 504 ? VAL B 510 ? TYR B 540 VAL B 546 Z 5 VAL B 583 ? TRP B 593 ? VAL B 619 TRP B 629 Z 6 CYS B 613 ? VAL B 617 ? CYS B 649 VAL B 653 Z 7 GLU B 663 ? GLY B 669 ? GLU B 699 GLY B 705 Z 8 GLN B 695 ? TYR B 699 ? GLN B 731 TYR B 735 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N LYS A 5 ? N LYS A 41 O GLN A 472 ? O GLN A 508 B 1 2 N ARG A 25 ? N ARG A 61 O LEU A 33 ? O LEU A 69 B 2 3 N GLN A 36 ? N GLN A 72 O ASN A 39 ? O ASN A 75 B 3 4 N ILE A 40 ? N ILE A 76 O PHE A 53 ? O PHE A 89 C 1 2 N ASN A 67 ? N ASN A 103 O GLU A 81 ? O GLU A 117 C 2 3 N LEU A 80 ? N LEU A 116 O ASP A 97 ? O ASP A 133 C 3 4 N ASP A 100 ? N ASP A 136 O GLN A 105 ? O GLN A 141 D 1 2 N TRP A 118 ? N TRP A 154 O VAL A 131 ? O VAL A 167 D 2 3 N TYR A 130 ? N TYR A 166 O TYR A 137 ? O TYR A 173 D 3 4 N VAL A 138 ? N VAL A 174 O TYR A 147 ? O TYR A 183 E 1 2 N TYR A 159 ? N TYR A 195 O PHE A 192 ? O PHE A 228 E 2 3 O ALA A 188 ? O ALA A 224 N TRP A 179 ? N TRP A 215 F 1 2 N TYR A 159 ? N TYR A 195 O PHE A 192 ? O PHE A 228 F 2 3 N ASN A 193 ? N ASN A 229 O THR A 229 ? O THR A 265 F 3 4 N PHE A 232 ? N PHE A 268 O ILE A 251 ? O ILE A 287 G 1 2 N TYR A 202 ? N TYR A 238 O VAL A 216 ? O VAL A 252 H 1 2 N THR A 268 ? N THR A 304 O SER A 276 ? O SER A 312 H 2 3 N ILE A 275 ? N ILE A 311 O CYS A 292 ? O CYS A 328 H 3 4 N ASP A 293 ? N ASP A 329 O ASN A 302 ? O ASN A 338 I 1 2 N THR A 268 ? N THR A 304 O SER A 276 ? O SER A 312 I 2 3 N ILE A 275 ? N ILE A 311 O CYS A 292 ? O CYS A 328 I 3 4 N MET A 289 ? N MET A 325 O HIS A 309 ? O HIS A 345 J 1 2 N HIS A 327 ? N HIS A 363 O TYR A 336 ? O TYR A 372 J 2 3 N PHE A 335 ? N PHE A 371 O PHE A 351 ? O PHE A 387 J 3 4 N TYR A 350 ? N TYR A 386 O THR A 359 ? O THR A 395 K 1 2 N ALA A 373 ? N ALA A 409 O TYR A 380 ? O TYR A 416 K 2 3 N TYR A 381 ? N TYR A 417 O TYR A 396 ? O TYR A 432 K 3 4 N LYS A 397 ? N LYS A 433 O THR A 407 ? O THR A 443 L 1 2 N SER A 422 ? N SER A 458 O ARG A 435 ? O ARG A 471 L 2 3 N CYS A 436 ? N CYS A 472 O LEU A 443 ? O LEU A 479 L 3 4 N TYR A 444 ? N TYR A 480 O GLU A 459 ? O GLU A 495 M 1 2 N ASP A 479 ? N ASP A 515 O TYR A 490 ? O TYR A 526 M 2 3 N ILE A 493 ? N ILE A 529 O VAL A 539 ? O VAL A 575 M 3 4 O ALA A 540 ? O ALA A 576 N ASP A 509 ? N ASP A 545 M 4 5 N VAL A 510 ? N VAL A 546 O TRP A 591 ? O TRP A 627 M 5 6 N GLY A 592 ? N GLY A 628 O VAL A 617 ? O VAL A 653 M 6 7 N ALA A 616 ? N ALA A 652 O ILE A 667 ? O ILE A 703 M 7 8 N TYR A 664 ? N TYR A 700 O GLN A 695 ? O GLN A 731 N 1 2 N LYS B 5 ? N LYS B 41 O GLN B 472 ? O GLN B 508 O 1 2 N ARG B 25 ? N ARG B 61 O LEU B 33 ? O LEU B 69 O 2 3 N TYR B 32 ? N TYR B 68 O PHE B 43 ? O PHE B 79 O 3 4 N ILE B 40 ? N ILE B 76 O PHE B 53 ? O PHE B 89 P 1 2 N SER B 70 ? N SER B 106 O LEU B 79 ? O LEU B 115 P 2 3 N LEU B 80 ? N LEU B 116 O ASP B 97 ? O ASP B 133 P 3 4 N ASP B 100 ? N ASP B 136 O GLN B 105 ? O GLN B 141 Q 1 2 N TRP B 118 ? N TRP B 154 O VAL B 131 ? O VAL B 167 Q 2 3 N TYR B 130 ? N TYR B 166 O TYR B 137 ? O TYR B 173 Q 3 4 N VAL B 138 ? N VAL B 174 O TYR B 147 ? O TYR B 183 R 1 2 N TYR B 159 ? N TYR B 195 O PHE B 192 ? O PHE B 228 R 2 3 O ALA B 188 ? O ALA B 224 N TRP B 179 ? N TRP B 215 S 1 2 N TYR B 159 ? N TYR B 195 O PHE B 192 ? O PHE B 228 S 2 3 N ASN B 193 ? N ASN B 229 O THR B 229 ? O THR B 265 S 3 4 N PHE B 232 ? N PHE B 268 O ILE B 251 ? O ILE B 287 T 1 2 N TYR B 202 ? N TYR B 238 O VAL B 216 ? O VAL B 252 U 1 2 N ALA B 270 ? N ALA B 306 O ARG B 274 ? O ARG B 310 U 2 3 N LEU B 277 ? N LEU B 313 O ASP B 290 ? O ASP B 326 U 3 4 N ASP B 293 ? N ASP B 329 O ASN B 302 ? O ASN B 338 V 1 2 N ALA B 270 ? N ALA B 306 O ARG B 274 ? O ARG B 310 V 2 3 N LEU B 277 ? N LEU B 313 O ASP B 290 ? O ASP B 326 V 3 4 N MET B 289 ? N MET B 325 O HIS B 309 ? O HIS B 345 W 1 2 N HIS B 327 ? N HIS B 363 O TYR B 336 ? O TYR B 372 W 2 3 N PHE B 335 ? N PHE B 371 O PHE B 351 ? O PHE B 387 W 3 4 N TYR B 350 ? N TYR B 386 O THR B 359 ? O THR B 395 X 1 2 N ALA B 373 ? N ALA B 409 O TYR B 380 ? O TYR B 416 X 2 3 N TYR B 381 ? N TYR B 417 O TYR B 396 ? O TYR B 432 X 3 4 N LYS B 397 ? N LYS B 433 O THR B 407 ? O THR B 443 Y 1 2 N SER B 424 ? N SER B 460 O GLN B 433 ? O GLN B 469 Y 2 3 N LEU B 434 ? N LEU B 470 O THR B 445 ? O THR B 481 Y 3 4 N TYR B 444 ? N TYR B 480 O GLU B 459 ? O GLU B 495 Z 1 2 N SER B 475 ? N SER B 511 O LEU B 494 ? O LEU B 530 Z 2 3 N ILE B 493 ? N ILE B 529 O VAL B 539 ? O VAL B 575 Z 3 4 O ALA B 540 ? O ALA B 576 N ASP B 509 ? N ASP B 545 Z 4 5 N LEU B 508 ? N LEU B 544 O ALA B 589 ? O ALA B 625 Z 5 6 N GLY B 592 ? N GLY B 628 O VAL B 617 ? O VAL B 653 Z 6 7 N ALA B 616 ? N ALA B 652 O LEU B 665 ? O LEU B 701 Z 7 8 N TYR B 664 ? N TYR B 700 O GLN B 695 ? O GLN B 731 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG A 851' AC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 1501' AC3 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 2191' AC4 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 2291' AC5 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 2292' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 2811' AC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 5201' AC8 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG B 851' AC9 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG B 921' BC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 1501' BC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG B 2191' BC3 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 2291' BC4 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG B 2292' BC5 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 5201' BC6 Software ? ? ? ? 12 'BINDING SITE FOR RESIDUE KXB A 1' BC7 Software ? ? ? ? 11 'BINDING SITE FOR RESIDUE KXB B 2' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 10 VAL A 42 ? VAL A 78 . ? 1_555 ? 2 AC1 10 ASN A 49 ? ASN A 85 . ? 1_555 ? 3 AC1 10 SER A 50 ? SER A 86 . ? 1_555 ? 4 AC1 10 SER A 51 ? SER A 87 . ? 1_555 ? 5 AC1 10 TYR A 350 ? TYR A 386 . ? 4_565 ? 6 AC1 10 GLN A 352 ? GLN A 388 . ? 4_565 ? 7 AC1 10 THR A 359 ? THR A 395 . ? 4_565 ? 8 AC1 10 HOH S . ? HOH A 810 . ? 1_555 ? 9 AC1 10 HOH S . ? HOH A 871 . ? 1_555 ? 10 AC1 10 HOH S . ? HOH A 994 . ? 4_565 ? 11 AC2 3 ARG A 111 ? ARG A 147 . ? 1_555 ? 12 AC2 3 ILE A 112 ? ILE A 148 . ? 1_555 ? 13 AC2 3 ASN A 114 ? ASN A 150 . ? 1_555 ? 14 AC3 4 ASN A 183 ? ASN A 219 . ? 1_555 ? 15 AC3 4 THR A 185 ? THR A 221 . ? 1_555 ? 16 AC3 4 GLN A 272 ? GLN A 308 . ? 1_555 ? 17 AC3 4 GLU A 273 ? GLU A 309 . ? 1_555 ? 18 AC4 3 ASN A 193 ? ASN A 229 . ? 1_555 ? 19 AC4 3 THR A 195 ? THR A 231 . ? 1_555 ? 20 AC4 3 NAG G . ? NAG A 2292 . ? 1_555 ? 21 AC5 1 NAG F . ? NAG A 2291 . ? 1_555 ? 22 AC6 3 TRP A 151 ? TRP A 187 . ? 1_555 ? 23 AC6 3 VAL A 243 ? VAL A 279 . ? 1_555 ? 24 AC6 3 ASN A 245 ? ASN A 281 . ? 1_555 ? 25 AC7 3 ASN A 484 ? ASN A 520 . ? 1_555 ? 26 AC7 3 ARG A 545 ? ARG A 581 . ? 1_555 ? 27 AC7 3 ASP A 569 ? ASP A 605 . ? 1_555 ? 28 AC8 8 GLU B 31 ? GLU B 67 . ? 1_555 ? 29 AC8 8 VAL B 42 ? VAL B 78 . ? 1_555 ? 30 AC8 8 ASN B 49 ? ASN B 85 . ? 1_555 ? 31 AC8 8 SER B 50 ? SER B 86 . ? 1_555 ? 32 AC8 8 SER B 51 ? SER B 87 . ? 1_555 ? 33 AC8 8 TYR B 350 ? TYR B 386 . ? 3_745 ? 34 AC8 8 GLN B 352 ? GLN B 388 . ? 3_745 ? 35 AC8 8 THR B 359 ? THR B 395 . ? 3_745 ? 36 AC9 3 GLU B 37 ? GLU B 73 . ? 1_555 ? 37 AC9 3 ASN B 39 ? ASN B 75 . ? 1_555 ? 38 AC9 3 ASN B 56 ? ASN B 92 . ? 1_555 ? 39 BC1 5 ARG B 111 ? ARG B 147 . ? 1_555 ? 40 BC1 5 ILE B 112 ? ILE B 148 . ? 1_555 ? 41 BC1 5 ASN B 114 ? ASN B 150 . ? 1_555 ? 42 BC1 5 ASP B 479 ? ASP B 515 . ? 1_455 ? 43 BC1 5 PHE B 480 ? PHE B 516 . ? 1_455 ? 44 BC2 3 ASN B 183 ? ASN B 219 . ? 1_555 ? 45 BC2 3 THR B 185 ? THR B 221 . ? 1_555 ? 46 BC2 3 GLU B 273 ? GLU B 309 . ? 1_555 ? 47 BC3 4 ILE B 158 ? ILE B 194 . ? 1_555 ? 48 BC3 4 ASN B 193 ? ASN B 229 . ? 1_555 ? 49 BC3 4 THR B 195 ? THR B 231 . ? 1_555 ? 50 BC3 4 NAG P . ? NAG B 2292 . ? 1_555 ? 51 BC4 1 NAG O . ? NAG B 2291 . ? 1_555 ? 52 BC5 5 LEU B 483 ? LEU B 519 . ? 1_555 ? 53 BC5 5 ASN B 484 ? ASN B 520 . ? 1_555 ? 54 BC5 5 ARG B 545 ? ARG B 581 . ? 1_555 ? 55 BC5 5 GLU B 568 ? GLU B 604 . ? 1_555 ? 56 BC5 5 ASP B 569 ? ASP B 605 . ? 1_555 ? 57 BC6 12 ARG A 89 ? ARG A 125 . ? 1_555 ? 58 BC6 12 GLU A 169 ? GLU A 205 . ? 1_555 ? 59 BC6 12 GLU A 170 ? GLU A 206 . ? 1_555 ? 60 BC6 12 TYR A 511 ? TYR A 547 . ? 1_555 ? 61 BC6 12 SER A 594 ? SER A 630 . ? 1_555 ? 62 BC6 12 VAL A 620 ? VAL A 656 . ? 1_555 ? 63 BC6 12 TYR A 626 ? TYR A 662 . ? 1_555 ? 64 BC6 12 TYR A 630 ? TYR A 666 . ? 1_555 ? 65 BC6 12 ASN A 674 ? ASN A 710 . ? 1_555 ? 66 BC6 12 HIS A 704 ? HIS A 740 . ? 1_555 ? 67 BC6 12 HOH S . ? HOH A 793 . ? 1_555 ? 68 BC6 12 HOH S . ? HOH A 923 . ? 1_555 ? 69 BC7 11 HOH T . ? HOH B 17 . ? 1_555 ? 70 BC7 11 ARG B 89 ? ARG B 125 . ? 1_555 ? 71 BC7 11 GLU B 169 ? GLU B 205 . ? 1_555 ? 72 BC7 11 GLU B 170 ? GLU B 206 . ? 1_555 ? 73 BC7 11 TYR B 511 ? TYR B 547 . ? 1_555 ? 74 BC7 11 SER B 594 ? SER B 630 . ? 1_555 ? 75 BC7 11 VAL B 620 ? VAL B 656 . ? 1_555 ? 76 BC7 11 TYR B 626 ? TYR B 662 . ? 1_555 ? 77 BC7 11 TYR B 630 ? TYR B 666 . ? 1_555 ? 78 BC7 11 ASN B 674 ? ASN B 710 . ? 1_555 ? 79 BC7 11 HIS B 704 ? HIS B 740 . ? 1_555 ? # _atom_sites.entry_id 3SWW _atom_sites.fract_transf_matrix[1][1] 0.015259 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.014721 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.002361 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C CL N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ARG A 1 4 ? 85.719 40.001 25.712 1.00 56.86 ? 40 ARG A N 1 ATOM 2 C CA . ARG A 1 4 ? 84.400 40.143 25.102 1.00 60.49 ? 40 ARG A CA 1 ATOM 3 C C . ARG A 1 4 ? 83.412 40.802 26.073 1.00 58.08 ? 40 ARG A C 1 ATOM 4 O O . ARG A 1 4 ? 83.337 40.437 27.250 1.00 55.78 ? 40 ARG A O 1 ATOM 5 C CB . ARG A 1 4 ? 83.874 38.784 24.621 1.00 63.94 ? 40 ARG A CB 1 ATOM 6 C CG . ARG A 1 4 ? 83.328 38.787 23.191 1.00 62.27 ? 40 ARG A CG 1 ATOM 7 N N . LYS A 1 5 ? 82.648 41.766 25.565 1.00 50.58 ? 41 LYS A N 1 ATOM 8 C CA . LYS A 1 5 ? 81.813 42.608 26.411 1.00 50.43 ? 41 LYS A CA 1 ATOM 9 C C . LYS A 1 5 ? 80.379 42.109 26.609 1.00 46.02 ? 41 LYS A C 1 ATOM 10 O O . LYS A 1 5 ? 79.870 41.287 25.846 1.00 46.85 ? 41 LYS A O 1 ATOM 11 C CB . LYS A 1 5 ? 81.806 44.045 25.889 1.00 48.40 ? 41 LYS A CB 1 ATOM 12 C CG . LYS A 1 5 ? 81.076 44.234 24.593 1.00 47.62 ? 41 LYS A CG 1 ATOM 13 C CD . LYS A 1 5 ? 81.260 45.647 24.082 1.00 49.83 ? 41 LYS A CD 1 ATOM 14 C CE . LYS A 1 5 ? 82.692 45.877 23.619 1.00 53.27 ? 41 LYS A CE 1 ATOM 15 N NZ . LYS A 1 5 ? 82.867 47.267 23.116 1.00 51.89 ? 41 LYS A NZ 1 ATOM 16 N N . THR A 1 6 ? 79.749 42.615 27.664 1.00 46.25 ? 42 THR A N 1 ATOM 17 C CA . THR A 1 6 ? 78.380 42.270 28.005 1.00 37.19 ? 42 THR A CA 1 ATOM 18 C C . THR A 1 6 ? 77.513 43.524 27.910 1.00 39.35 ? 42 THR A C 1 ATOM 19 O O . THR A 1 6 ? 78.036 44.628 27.685 1.00 35.19 ? 42 THR A O 1 ATOM 20 C CB . THR A 1 6 ? 78.293 41.690 29.433 1.00 38.09 ? 42 THR A CB 1 ATOM 21 O OG1 . THR A 1 6 ? 78.852 42.620 30.379 1.00 38.75 ? 42 THR A OG1 1 ATOM 22 C CG2 . THR A 1 6 ? 79.050 40.373 29.526 1.00 36.78 ? 42 THR A CG2 1 ATOM 23 N N . TYR A 1 7 ? 76.198 43.348 28.070 1.00 31.94 ? 43 TYR A N 1 ATOM 24 C CA . TYR A 1 7 ? 75.263 44.467 28.175 1.00 31.92 ? 43 TYR A CA 1 ATOM 25 C C . TYR A 1 7 ? 75.231 44.923 29.635 1.00 32.41 ? 43 TYR A C 1 ATOM 26 O O . TYR A 1 7 ? 74.668 44.237 30.491 1.00 31.04 ? 43 TYR A O 1 ATOM 27 C CB . TYR A 1 7 ? 73.865 44.032 27.734 1.00 29.02 ? 43 TYR A CB 1 ATOM 28 C CG . TYR A 1 7 ? 72.840 45.148 27.651 1.00 30.80 ? 43 TYR A CG 1 ATOM 29 C CD1 . TYR A 1 7 ? 72.714 45.915 26.511 1.00 32.16 ? 43 TYR A CD1 1 ATOM 30 C CD2 . TYR A 1 7 ? 71.977 45.409 28.708 1.00 29.76 ? 43 TYR A CD2 1 ATOM 31 C CE1 . TYR A 1 7 ? 71.767 46.917 26.424 1.00 31.30 ? 43 TYR A CE1 1 ATOM 32 C CE2 . TYR A 1 7 ? 71.030 46.413 28.631 1.00 28.60 ? 43 TYR A CE2 1 ATOM 33 C CZ . TYR A 1 7 ? 70.932 47.165 27.491 1.00 30.19 ? 43 TYR A CZ 1 ATOM 34 O OH . TYR A 1 7 ? 69.993 48.167 27.402 1.00 30.10 ? 43 TYR A OH 1 ATOM 35 N N . THR A 1 8 ? 75.841 46.068 29.913 1.00 29.86 ? 44 THR A N 1 ATOM 36 C CA . THR A 1 8 ? 76.112 46.467 31.286 1.00 34.47 ? 44 THR A CA 1 ATOM 37 C C . THR A 1 8 ? 75.009 47.368 31.838 1.00 32.80 ? 44 THR A C 1 ATOM 38 O O . THR A 1 8 ? 74.128 47.812 31.092 1.00 31.28 ? 44 THR A O 1 ATOM 39 C CB . THR A 1 8 ? 77.445 47.232 31.371 1.00 34.71 ? 44 THR A CB 1 ATOM 40 O OG1 . THR A 1 8 ? 77.311 48.481 30.679 1.00 33.49 ? 44 THR A OG1 1 ATOM 41 C CG2 . THR A 1 8 ? 78.584 46.416 30.730 1.00 37.69 ? 44 THR A CG2 1 ATOM 42 N N . LEU A 1 9 ? 75.076 47.660 33.138 1.00 33.19 ? 45 LEU A N 1 ATOM 43 C CA . LEU A 1 9 ? 74.115 48.583 33.741 1.00 30.71 ? 45 LEU A CA 1 ATOM 44 C C . LEU A 1 9 ? 74.187 49.950 33.063 1.00 29.48 ? 45 LEU A C 1 ATOM 45 O O . LEU A 1 9 ? 73.167 50.554 32.766 1.00 34.04 ? 45 LEU A O 1 ATOM 46 C CB . LEU A 1 9 ? 74.351 48.727 35.244 1.00 31.78 ? 45 LEU A CB 1 ATOM 47 C CG . LEU A 1 9 ? 73.347 49.605 36.006 1.00 31.50 ? 45 LEU A CG 1 ATOM 48 C CD1 . LEU A 1 9 ? 71.922 49.049 35.909 1.00 26.81 ? 45 LEU A CD1 1 ATOM 49 C CD2 . LEU A 1 9 ? 73.780 49.738 37.457 1.00 30.31 ? 45 LEU A CD2 1 ATOM 50 N N . THR A 1 10 ? 75.393 50.431 32.799 1.00 32.30 ? 46 THR A N 1 ATOM 51 C CA . THR A 1 10 ? 75.556 51.751 32.188 1.00 34.65 ? 46 THR A CA 1 ATOM 52 C C . THR A 1 10 ? 74.981 51.824 30.770 1.00 32.42 ? 46 THR A C 1 ATOM 53 O O . THR A 1 10 ? 74.446 52.852 30.371 1.00 36.66 ? 46 THR A O 1 ATOM 54 C CB . THR A 1 10 ? 77.030 52.221 32.176 1.00 39.92 ? 46 THR A CB 1 ATOM 55 O OG1 . THR A 1 10 ? 77.584 52.120 33.494 1.00 41.19 ? 46 THR A OG1 1 ATOM 56 C CG2 . THR A 1 10 ? 77.121 53.676 31.722 1.00 41.61 ? 46 THR A CG2 1 ATOM 57 N N . ASP A 1 11 ? 75.100 50.738 30.012 1.00 35.42 ? 47 ASP A N 1 ATOM 58 C CA . ASP A 1 11 ? 74.510 50.661 28.678 1.00 31.09 ? 47 ASP A CA 1 ATOM 59 C C . ASP A 1 11 ? 72.993 50.825 28.742 1.00 33.21 ? 47 ASP A C 1 ATOM 60 O O . ASP A 1 11 ? 72.403 51.550 27.929 1.00 33.37 ? 47 ASP A O 1 ATOM 61 C CB . ASP A 1 11 ? 74.850 49.326 28.015 1.00 30.06 ? 47 ASP A CB 1 ATOM 62 C CG . ASP A 1 11 ? 76.321 49.227 27.609 1.00 35.81 ? 47 ASP A CG 1 ATOM 63 O OD1 . ASP A 1 11 ? 76.939 50.268 27.284 1.00 35.02 ? 47 ASP A OD1 1 ATOM 64 O OD2 . ASP A 1 11 ? 76.856 48.103 27.618 1.00 33.53 ? 47 ASP A OD2 1 ATOM 65 N N . TYR A 1 12 ? 72.369 50.124 29.689 1.00 29.27 ? 48 TYR A N 1 ATOM 66 C CA . TYR A 1 12 ? 70.943 50.291 29.945 1.00 30.25 ? 48 TYR A CA 1 ATOM 67 C C . TYR A 1 12 ? 70.627 51.743 30.319 1.00 32.74 ? 48 TYR A C 1 ATOM 68 O O . TYR A 1 12 ? 69.856 52.419 29.642 1.00 34.40 ? 48 TYR A O 1 ATOM 69 C CB . TYR A 1 12 ? 70.446 49.339 31.046 1.00 29.43 ? 48 TYR A CB 1 ATOM 70 C CG . TYR A 1 12 ? 69.019 49.637 31.457 1.00 30.83 ? 48 TYR A CG 1 ATOM 71 C CD1 . TYR A 1 12 ? 67.988 49.611 30.525 1.00 30.29 ? 48 TYR A CD1 1 ATOM 72 C CD2 . TYR A 1 12 ? 68.706 49.972 32.768 1.00 31.80 ? 48 TYR A CD2 1 ATOM 73 C CE1 . TYR A 1 12 ? 66.675 49.902 30.891 1.00 29.15 ? 48 TYR A CE1 1 ATOM 74 C CE2 . TYR A 1 12 ? 67.401 50.260 33.143 1.00 29.46 ? 48 TYR A CE2 1 ATOM 75 C CZ . TYR A 1 12 ? 66.392 50.231 32.195 1.00 32.75 ? 48 TYR A CZ 1 ATOM 76 O OH . TYR A 1 12 ? 65.091 50.517 32.560 1.00 33.85 ? 48 TYR A OH 1 ATOM 77 N N . LEU A 1 13 ? 71.242 52.228 31.389 1.00 34.44 ? 49 LEU A N 1 ATOM 78 C CA . LEU A 1 13 ? 70.992 53.585 31.858 1.00 31.34 ? 49 LEU A CA 1 ATOM 79 C C . LEU A 1 13 ? 71.285 54.694 30.841 1.00 36.50 ? 49 LEU A C 1 ATOM 80 O O . LEU A 1 13 ? 70.542 55.673 30.763 1.00 34.43 ? 49 LEU A O 1 ATOM 81 C CB . LEU A 1 13 ? 71.788 53.833 33.137 1.00 33.94 ? 49 LEU A CB 1 ATOM 82 C CG . LEU A 1 13 ? 71.350 52.949 34.311 1.00 30.34 ? 49 LEU A CG 1 ATOM 83 C CD1 . LEU A 1 13 ? 72.093 53.365 35.565 1.00 26.79 ? 49 LEU A CD1 1 ATOM 84 C CD2 . LEU A 1 13 ? 69.839 53.075 34.506 1.00 29.40 ? 49 LEU A CD2 1 ATOM 85 N N . LYS A 1 14 ? 72.367 54.552 30.074 1.00 33.66 ? 50 LYS A N 1 ATOM 86 C CA . LYS A 1 14 ? 72.792 55.615 29.159 1.00 38.05 ? 50 LYS A CA 1 ATOM 87 C C . LYS A 1 14 ? 72.366 55.406 27.690 1.00 41.60 ? 50 LYS A C 1 ATOM 88 O O . LYS A 1 14 ? 72.650 56.248 26.827 1.00 41.14 ? 50 LYS A O 1 ATOM 89 C CB . LYS A 1 14 ? 74.312 55.811 29.235 1.00 39.50 ? 50 LYS A CB 1 ATOM 90 C CG . LYS A 1 14 ? 74.821 56.209 30.604 1.00 40.05 ? 50 LYS A CG 1 ATOM 91 C CD . LYS A 1 14 ? 74.320 57.591 30.989 1.00 45.49 ? 50 LYS A CD 1 ATOM 92 C CE . LYS A 1 14 ? 74.821 57.982 32.369 1.00 51.88 ? 50 LYS A CE 1 ATOM 93 N NZ . LYS A 1 14 ? 74.519 59.406 32.664 1.00 60.13 ? 50 LYS A NZ 1 ATOM 94 N N . ASN A 1 15 ? 71.714 54.282 27.403 1.00 38.19 ? 51 ASN A N 1 ATOM 95 C CA . ASN A 1 15 ? 71.167 54.042 26.074 1.00 37.65 ? 51 ASN A CA 1 ATOM 96 C C . ASN A 1 15 ? 72.235 53.873 25.006 1.00 41.05 ? 51 ASN A C 1 ATOM 97 O O . ASN A 1 15 ? 72.123 54.424 23.911 1.00 41.31 ? 51 ASN A O 1 ATOM 98 C CB . ASN A 1 15 ? 70.267 55.204 25.676 1.00 44.39 ? 51 ASN A CB 1 ATOM 99 C CG . ASN A 1 15 ? 68.817 54.822 25.638 1.00 53.50 ? 51 ASN A CG 1 ATOM 100 O OD1 . ASN A 1 15 ? 68.275 54.522 24.570 1.00 55.66 ? 51 ASN A OD1 1 ATOM 101 N ND2 . ASN A 1 15 ? 68.168 54.824 26.808 1.00 47.71 ? 51 ASN A ND2 1 ATOM 102 N N . THR A 1 16 ? 73.274 53.118 25.330 1.00 38.67 ? 52 THR A N 1 ATOM 103 C CA . THR A 1 16 ? 74.376 52.886 24.414 1.00 35.98 ? 52 THR A CA 1 ATOM 104 C C . THR A 1 16 ? 73.880 52.252 23.109 1.00 42.05 ? 52 THR A C 1 ATOM 105 O O . THR A 1 16 ? 74.316 52.614 22.018 1.00 38.81 ? 52 THR A O 1 ATOM 106 C CB . THR A 1 16 ? 75.412 51.952 25.066 1.00 38.39 ? 52 THR A CB 1 ATOM 107 O OG1 . THR A 1 16 ? 75.943 52.567 26.254 1.00 37.92 ? 52 THR A OG1 1 ATOM 108 C CG2 . THR A 1 16 ? 76.537 51.644 24.099 1.00 40.63 ? 52 THR A CG2 1 ATOM 109 N N . TYR A 1 17 ? 72.967 51.297 23.231 1.00 41.78 ? 53 TYR A N 1 ATOM 110 C CA . TYR A 1 17 ? 72.441 50.590 22.071 1.00 37.71 ? 53 TYR A CA 1 ATOM 111 C C . TYR A 1 17 ? 70.994 50.994 21.835 1.00 42.23 ? 53 TYR A C 1 ATOM 112 O O . TYR A 1 17 ? 70.099 50.555 22.555 1.00 42.72 ? 53 TYR A O 1 ATOM 113 C CB . TYR A 1 17 ? 72.572 49.085 22.291 1.00 36.06 ? 53 TYR A CB 1 ATOM 114 C CG . TYR A 1 17 ? 74.001 48.666 22.574 1.00 36.31 ? 53 TYR A CG 1 ATOM 115 C CD1 . TYR A 1 17 ? 74.937 48.592 21.549 1.00 35.85 ? 53 TYR A CD1 1 ATOM 116 C CD2 . TYR A 1 17 ? 74.419 48.362 23.863 1.00 37.19 ? 53 TYR A CD2 1 ATOM 117 C CE1 . TYR A 1 17 ? 76.249 48.221 21.799 1.00 39.82 ? 53 TYR A CE1 1 ATOM 118 C CE2 . TYR A 1 17 ? 75.726 47.984 24.123 1.00 35.80 ? 53 TYR A CE2 1 ATOM 119 C CZ . TYR A 1 17 ? 76.637 47.913 23.084 1.00 40.62 ? 53 TYR A CZ 1 ATOM 120 O OH . TYR A 1 17 ? 77.937 47.540 23.328 1.00 39.33 ? 53 TYR A OH 1 ATOM 121 N N . ARG A 1 18 ? 70.769 51.845 20.835 1.00 41.00 ? 54 ARG A N 1 ATOM 122 C CA . ARG A 1 18 ? 69.439 52.405 20.605 1.00 44.08 ? 54 ARG A CA 1 ATOM 123 C C . ARG A 1 18 ? 68.651 51.628 19.551 1.00 41.97 ? 54 ARG A C 1 ATOM 124 O O . ARG A 1 18 ? 69.210 51.197 18.543 1.00 41.60 ? 54 ARG A O 1 ATOM 125 C CB . ARG A 1 18 ? 69.536 53.882 20.207 1.00 48.02 ? 54 ARG A CB 1 ATOM 126 C CG . ARG A 1 18 ? 69.931 54.820 21.354 1.00 54.77 ? 54 ARG A CG 1 ATOM 127 C CD . ARG A 1 18 ? 69.809 56.285 20.945 1.00 58.73 ? 54 ARG A CD 1 ATOM 128 N N . LEU A 1 19 ? 67.358 51.446 19.808 1.00 38.09 ? 55 LEU A N 1 ATOM 129 C CA . LEU A 1 19 ? 66.430 50.867 18.844 1.00 38.01 ? 55 LEU A CA 1 ATOM 130 C C . LEU A 1 19 ? 65.897 51.985 17.968 1.00 41.95 ? 55 LEU A C 1 ATOM 131 O O . LEU A 1 19 ? 65.469 53.020 18.487 1.00 39.95 ? 55 LEU A O 1 ATOM 132 C CB . LEU A 1 19 ? 65.248 50.209 19.556 1.00 34.06 ? 55 LEU A CB 1 ATOM 133 C CG . LEU A 1 19 ? 65.450 48.804 20.112 1.00 37.62 ? 55 LEU A CG 1 ATOM 134 C CD1 . LEU A 1 19 ? 64.289 48.421 21.012 1.00 38.67 ? 55 LEU A CD1 1 ATOM 135 C CD2 . LEU A 1 19 ? 65.571 47.835 18.962 1.00 39.21 ? 55 LEU A CD2 1 ATOM 136 N N . LYS A 1 20 ? 65.913 51.775 16.651 1.00 34.42 ? 56 LYS A N 1 ATOM 137 C CA . LYS A 1 20 ? 65.413 52.773 15.702 1.00 37.02 ? 56 LYS A CA 1 ATOM 138 C C . LYS A 1 20 ? 63.934 52.544 15.447 1.00 36.28 ? 56 LYS A C 1 ATOM 139 O O . LYS A 1 20 ? 63.446 51.414 15.497 1.00 34.90 ? 56 LYS A O 1 ATOM 140 C CB . LYS A 1 20 ? 66.175 52.727 14.374 1.00 36.83 ? 56 LYS A CB 1 ATOM 141 C CG . LYS A 1 20 ? 67.624 53.222 14.439 1.00 41.39 ? 56 LYS A CG 1 ATOM 142 C CD . LYS A 1 20 ? 68.119 53.650 13.030 1.00 49.77 ? 56 LYS A CD 1 ATOM 143 C CE . LYS A 1 20 ? 69.400 52.912 12.566 1.00 53.08 ? 56 LYS A CE 1 ATOM 144 N NZ . LYS A 1 20 ? 69.187 51.777 11.581 1.00 44.90 ? 56 LYS A NZ 1 ATOM 145 N N . LEU A 1 21 ? 63.221 53.625 15.177 1.00 35.25 ? 57 LEU A N 1 ATOM 146 C CA . LEU A 1 21 ? 61.792 53.546 14.973 1.00 38.64 ? 57 LEU A CA 1 ATOM 147 C C . LEU A 1 21 ? 61.453 54.085 13.587 1.00 37.58 ? 57 LEU A C 1 ATOM 148 O O . LEU A 1 21 ? 62.324 54.571 12.854 1.00 40.96 ? 57 LEU A O 1 ATOM 149 C CB . LEU A 1 21 ? 61.045 54.352 16.050 1.00 37.96 ? 57 LEU A CB 1 ATOM 150 C CG . LEU A 1 21 ? 61.602 54.320 17.475 1.00 48.22 ? 57 LEU A CG 1 ATOM 151 C CD1 . LEU A 1 21 ? 60.730 55.149 18.418 1.00 53.10 ? 57 LEU A CD1 1 ATOM 152 C CD2 . LEU A 1 21 ? 61.730 52.891 17.982 1.00 43.51 ? 57 LEU A CD2 1 ATOM 153 N N . TYR A 1 22 ? 60.185 53.983 13.219 1.00 32.04 ? 58 TYR A N 1 ATOM 154 C CA . TYR A 1 22 ? 59.711 54.637 12.016 1.00 32.59 ? 58 TYR A CA 1 ATOM 155 C C . TYR A 1 22 ? 58.295 55.096 12.300 1.00 31.30 ? 58 TYR A C 1 ATOM 156 O O . TYR A 1 22 ? 57.324 54.400 11.984 1.00 31.77 ? 58 TYR A O 1 ATOM 157 C CB . TYR A 1 22 ? 59.761 53.695 10.808 1.00 30.64 ? 58 TYR A CB 1 ATOM 158 C CG . TYR A 1 22 ? 59.745 54.425 9.486 1.00 30.56 ? 58 TYR A CG 1 ATOM 159 C CD1 . TYR A 1 22 ? 58.552 54.846 8.917 1.00 31.01 ? 58 TYR A CD1 1 ATOM 160 C CD2 . TYR A 1 22 ? 60.923 54.707 8.811 1.00 31.05 ? 58 TYR A CD2 1 ATOM 161 C CE1 . TYR A 1 22 ? 58.533 55.518 7.706 1.00 30.78 ? 58 TYR A CE1 1 ATOM 162 C CE2 . TYR A 1 22 ? 60.911 55.384 7.596 1.00 32.91 ? 58 TYR A CE2 1 ATOM 163 C CZ . TYR A 1 22 ? 59.713 55.777 7.047 1.00 32.00 ? 58 TYR A CZ 1 ATOM 164 O OH . TYR A 1 22 ? 59.689 56.446 5.835 1.00 31.63 ? 58 TYR A OH 1 ATOM 165 N N . SER A 1 23 ? 58.191 56.264 12.924 1.00 32.17 ? 59 SER A N 1 ATOM 166 C CA . SER A 1 23 ? 56.908 56.859 13.250 1.00 31.93 ? 59 SER A CA 1 ATOM 167 C C . SER A 1 23 ? 56.436 57.712 12.091 1.00 29.59 ? 59 SER A C 1 ATOM 168 O O . SER A 1 23 ? 57.073 58.695 11.728 1.00 34.36 ? 59 SER A O 1 ATOM 169 C CB . SER A 1 23 ? 57.023 57.721 14.507 1.00 35.66 ? 59 SER A CB 1 ATOM 170 O OG . SER A 1 23 ? 57.519 56.947 15.594 1.00 40.95 ? 59 SER A OG 1 ATOM 171 N N . LEU A 1 24 ? 55.311 57.341 11.506 1.00 28.82 ? 60 LEU A N 1 ATOM 172 C CA . LEU A 1 24 ? 54.776 58.115 10.406 1.00 31.67 ? 60 LEU A CA 1 ATOM 173 C C . LEU A 1 24 ? 53.351 58.567 10.710 1.00 31.76 ? 60 LEU A C 1 ATOM 174 O O . LEU A 1 24 ? 52.674 57.997 11.568 1.00 32.18 ? 60 LEU A O 1 ATOM 175 C CB . LEU A 1 24 ? 54.847 57.309 9.101 1.00 31.61 ? 60 LEU A CB 1 ATOM 176 C CG . LEU A 1 24 ? 54.197 55.928 9.069 1.00 30.33 ? 60 LEU A CG 1 ATOM 177 C CD1 . LEU A 1 24 ? 52.676 56.047 9.081 1.00 29.88 ? 60 LEU A CD1 1 ATOM 178 C CD2 . LEU A 1 24 ? 54.655 55.169 7.835 1.00 30.90 ? 60 LEU A CD2 1 ATOM 179 N N . ARG A 1 25 ? 52.908 59.604 10.009 1.00 32.34 ? 61 ARG A N 1 ATOM 180 C CA . ARG A 1 25 ? 51.566 60.126 10.186 1.00 35.43 ? 61 ARG A CA 1 ATOM 181 C C . ARG A 1 25 ? 50.923 60.134 8.821 1.00 30.84 ? 61 ARG A C 1 ATOM 182 O O . ARG A 1 25 ? 51.326 60.902 7.953 1.00 30.82 ? 61 ARG A O 1 ATOM 183 C CB . ARG A 1 25 ? 51.597 61.553 10.768 1.00 35.39 ? 61 ARG A CB 1 ATOM 184 C CG . ARG A 1 25 ? 52.396 61.690 12.091 1.00 44.44 ? 61 ARG A CG 1 ATOM 185 C CD . ARG A 1 25 ? 52.537 63.168 12.557 1.00 49.46 ? 61 ARG A CD 1 ATOM 186 N NE . ARG A 1 25 ? 53.285 63.308 13.813 1.00 53.13 ? 61 ARG A NE 1 ATOM 187 C CZ . ARG A 1 25 ? 53.291 64.409 14.569 1.00 53.35 ? 61 ARG A CZ 1 ATOM 188 N NH1 . ARG A 1 25 ? 52.589 65.470 14.200 1.00 51.16 ? 61 ARG A NH1 1 ATOM 189 N NH2 . ARG A 1 25 ? 53.997 64.452 15.697 1.00 50.13 ? 61 ARG A NH2 1 ATOM 190 N N . TRP A 1 26 ? 49.942 59.264 8.627 1.00 26.28 ? 62 TRP A N 1 ATOM 191 C CA . TRP A 1 26 ? 49.191 59.251 7.393 1.00 32.04 ? 62 TRP A CA 1 ATOM 192 C C . TRP A 1 26 ? 48.430 60.559 7.288 1.00 34.45 ? 62 TRP A C 1 ATOM 193 O O . TRP A 1 26 ? 47.801 60.991 8.253 1.00 30.97 ? 62 TRP A O 1 ATOM 194 C CB . TRP A 1 26 ? 48.226 58.078 7.381 1.00 30.07 ? 62 TRP A CB 1 ATOM 195 C CG . TRP A 1 26 ? 48.889 56.747 7.204 1.00 31.91 ? 62 TRP A CG 1 ATOM 196 C CD1 . TRP A 1 26 ? 49.042 55.772 8.151 1.00 29.54 ? 62 TRP A CD1 1 ATOM 197 C CD2 . TRP A 1 26 ? 49.475 56.235 6.001 1.00 26.77 ? 62 TRP A CD2 1 ATOM 198 N NE1 . TRP A 1 26 ? 49.693 54.686 7.607 1.00 29.33 ? 62 TRP A NE1 1 ATOM 199 C CE2 . TRP A 1 26 ? 49.966 54.946 6.290 1.00 31.05 ? 62 TRP A CE2 1 ATOM 200 C CE3 . TRP A 1 26 ? 49.644 56.745 4.713 1.00 29.97 ? 62 TRP A CE3 1 ATOM 201 C CZ2 . TRP A 1 26 ? 50.612 54.163 5.339 1.00 29.55 ? 62 TRP A CZ2 1 ATOM 202 C CZ3 . TRP A 1 26 ? 50.277 55.965 3.772 1.00 30.80 ? 62 TRP A CZ3 1 ATOM 203 C CH2 . TRP A 1 26 ? 50.761 54.692 4.090 1.00 29.76 ? 62 TRP A CH2 1 ATOM 204 N N . ILE A 1 27 ? 48.495 61.200 6.127 1.00 29.71 ? 63 ILE A N 1 ATOM 205 C CA . ILE A 1 27 ? 47.774 62.449 5.921 1.00 31.10 ? 63 ILE A CA 1 ATOM 206 C C . ILE A 1 27 ? 46.718 62.314 4.845 1.00 30.73 ? 63 ILE A C 1 ATOM 207 O O . ILE A 1 27 ? 46.010 63.274 4.542 1.00 33.25 ? 63 ILE A O 1 ATOM 208 C CB . ILE A 1 27 ? 48.716 63.590 5.520 1.00 38.23 ? 63 ILE A CB 1 ATOM 209 C CG1 . ILE A 1 27 ? 49.494 63.206 4.261 1.00 33.05 ? 63 ILE A CG1 1 ATOM 210 C CG2 . ILE A 1 27 ? 49.658 63.928 6.666 1.00 28.97 ? 63 ILE A CG2 1 ATOM 211 C CD1 . ILE A 1 27 ? 50.306 64.337 3.699 1.00 36.20 ? 63 ILE A CD1 1 ATOM 212 N N . SER A 1 28 ? 46.620 61.122 4.265 1.00 32.08 ? 64 SER A N 1 ATOM 213 C CA . SER A 1 28 ? 45.626 60.843 3.235 1.00 31.10 ? 64 SER A CA 1 ATOM 214 C C . SER A 1 28 ? 45.597 59.352 2.934 1.00 33.32 ? 64 SER A C 1 ATOM 215 O O . SER A 1 28 ? 46.188 58.553 3.656 1.00 34.75 ? 64 SER A O 1 ATOM 216 C CB . SER A 1 28 ? 45.938 61.629 1.963 1.00 33.87 ? 64 SER A CB 1 ATOM 217 O OG . SER A 1 28 ? 46.971 60.985 1.232 1.00 36.46 ? 64 SER A OG 1 ATOM 218 N N . ASP A 1 29 ? 44.913 58.962 1.866 1.00 34.77 ? 65 ASP A N 1 ATOM 219 C CA . ASP A 1 29 ? 44.871 57.546 1.511 1.00 38.49 ? 65 ASP A CA 1 ATOM 220 C C . ASP A 1 29 ? 46.193 57.033 0.922 1.00 37.22 ? 65 ASP A C 1 ATOM 221 O O . ASP A 1 29 ? 46.403 55.823 0.816 1.00 34.61 ? 65 ASP A O 1 ATOM 222 C CB . ASP A 1 29 ? 43.713 57.244 0.552 1.00 41.16 ? 65 ASP A CB 1 ATOM 223 C CG . ASP A 1 29 ? 43.431 55.745 0.432 1.00 48.37 ? 65 ASP A CG 1 ATOM 224 O OD1 . ASP A 1 29 ? 43.812 54.996 1.363 1.00 44.99 ? 65 ASP A OD1 1 ATOM 225 O OD2 . ASP A 1 29 ? 42.840 55.312 -0.588 1.00 55.02 ? 65 ASP A OD2 1 ATOM 226 N N . HIS A 1 30 ? 47.091 57.938 0.550 1.00 34.32 ? 66 HIS A N 1 ATOM 227 C CA . HIS A 1 30 ? 48.305 57.487 -0.122 1.00 37.77 ? 66 HIS A CA 1 ATOM 228 C C . HIS A 1 30 ? 49.595 58.221 0.228 1.00 34.34 ? 66 HIS A C 1 ATOM 229 O O . HIS A 1 30 ? 50.623 57.962 -0.386 1.00 34.33 ? 66 HIS A O 1 ATOM 230 C CB . HIS A 1 30 ? 48.107 57.539 -1.630 1.00 39.64 ? 66 HIS A CB 1 ATOM 231 C CG . HIS A 1 30 ? 48.041 58.928 -2.176 1.00 45.00 ? 66 HIS A CG 1 ATOM 232 N ND1 . HIS A 1 30 ? 46.955 59.753 -1.974 1.00 47.29 ? 66 HIS A ND1 1 ATOM 233 C CD2 . HIS A 1 30 ? 48.920 59.637 -2.928 1.00 47.07 ? 66 HIS A CD2 1 ATOM 234 C CE1 . HIS A 1 30 ? 47.172 60.914 -2.572 1.00 54.17 ? 66 HIS A CE1 1 ATOM 235 N NE2 . HIS A 1 30 ? 48.357 60.870 -3.159 1.00 50.05 ? 66 HIS A NE2 1 ATOM 236 N N . GLU A 1 31 ? 49.546 59.136 1.189 1.00 28.81 ? 67 GLU A N 1 ATOM 237 C CA . GLU A 1 31 ? 50.726 59.906 1.580 1.00 31.78 ? 67 GLU A CA 1 ATOM 238 C C . GLU A 1 31 ? 50.893 59.935 3.097 1.00 33.99 ? 67 GLU A C 1 ATOM 239 O O . GLU A 1 31 ? 49.901 59.896 3.834 1.00 29.78 ? 67 GLU A O 1 ATOM 240 C CB . GLU A 1 31 ? 50.636 61.344 1.061 1.00 34.05 ? 67 GLU A CB 1 ATOM 241 C CG . GLU A 1 31 ? 50.926 61.497 -0.427 1.00 39.36 ? 67 GLU A CG 1 ATOM 242 C CD . GLU A 1 31 ? 50.949 62.958 -0.875 1.00 42.31 ? 67 GLU A CD 1 ATOM 243 O OE1 . GLU A 1 31 ? 50.226 63.787 -0.280 1.00 46.67 ? 67 GLU A OE1 1 ATOM 244 O OE2 . GLU A 1 31 ? 51.700 63.284 -1.815 1.00 38.70 ? 67 GLU A OE2 1 ATOM 245 N N . TYR A 1 32 ? 52.143 59.997 3.557 1.00 31.83 ? 68 TYR A N 1 ATOM 246 C CA . TYR A 1 32 ? 52.423 60.129 4.987 1.00 30.59 ? 68 TYR A CA 1 ATOM 247 C C . TYR A 1 32 ? 53.536 61.131 5.301 1.00 31.97 ? 68 TYR A C 1 ATOM 248 O O . TYR A 1 32 ? 54.364 61.433 4.441 1.00 31.93 ? 68 TYR A O 1 ATOM 249 C CB . TYR A 1 32 ? 52.703 58.767 5.634 1.00 30.79 ? 68 TYR A CB 1 ATOM 250 C CG . TYR A 1 32 ? 53.972 58.052 5.201 1.00 27.83 ? 68 TYR A CG 1 ATOM 251 C CD1 . TYR A 1 32 ? 55.203 58.393 5.741 1.00 28.74 ? 68 TYR A CD1 1 ATOM 252 C CD2 . TYR A 1 32 ? 53.920 56.986 4.309 1.00 30.38 ? 68 TYR A CD2 1 ATOM 253 C CE1 . TYR A 1 32 ? 56.354 57.727 5.372 1.00 29.45 ? 68 TYR A CE1 1 ATOM 254 C CE2 . TYR A 1 32 ? 55.070 56.310 3.926 1.00 29.22 ? 68 TYR A CE2 1 ATOM 255 C CZ . TYR A 1 32 ? 56.278 56.685 4.460 1.00 31.15 ? 68 TYR A CZ 1 ATOM 256 O OH . TYR A 1 32 ? 57.415 56.023 4.094 1.00 30.19 ? 68 TYR A OH 1 ATOM 257 N N . LEU A 1 33 ? 53.526 61.658 6.531 1.00 29.50 ? 69 LEU A N 1 ATOM 258 C CA . LEU A 1 33 ? 54.582 62.536 7.031 1.00 29.20 ? 69 LEU A CA 1 ATOM 259 C C . LEU A 1 33 ? 55.571 61.742 7.843 1.00 28.84 ? 69 LEU A C 1 ATOM 260 O O . LEU A 1 33 ? 55.193 60.842 8.599 1.00 30.46 ? 69 LEU A O 1 ATOM 261 C CB . LEU A 1 33 ? 54.013 63.646 7.917 1.00 32.21 ? 69 LEU A CB 1 ATOM 262 C CG . LEU A 1 33 ? 53.141 64.655 7.182 1.00 29.31 ? 69 LEU A CG 1 ATOM 263 C CD1 . LEU A 1 33 ? 52.539 65.664 8.144 1.00 34.80 ? 69 LEU A CD1 1 ATOM 264 C CD2 . LEU A 1 33 ? 53.968 65.333 6.140 1.00 32.61 ? 69 LEU A CD2 1 ATOM 265 N N . TYR A 1 34 ? 56.842 62.092 7.692 1.00 32.07 ? 70 TYR A N 1 ATOM 266 C CA . TYR A 1 34 ? 57.922 61.446 8.423 1.00 35.60 ? 70 TYR A CA 1 ATOM 267 C C . TYR A 1 34 ? 59.032 62.460 8.686 1.00 39.40 ? 70 TYR A C 1 ATOM 268 O O . TYR A 1 34 ? 59.455 63.178 7.778 1.00 37.96 ? 70 TYR A O 1 ATOM 269 C CB . TYR A 1 34 ? 58.459 60.273 7.614 1.00 32.44 ? 70 TYR A CB 1 ATOM 270 C CG . TYR A 1 34 ? 59.612 59.538 8.258 1.00 32.66 ? 70 TYR A CG 1 ATOM 271 C CD1 . TYR A 1 34 ? 59.413 58.704 9.346 1.00 33.99 ? 70 TYR A CD1 1 ATOM 272 C CD2 . TYR A 1 34 ? 60.903 59.659 7.754 1.00 39.00 ? 70 TYR A CD2 1 ATOM 273 C CE1 . TYR A 1 34 ? 60.478 58.025 9.938 1.00 36.43 ? 70 TYR A CE1 1 ATOM 274 C CE2 . TYR A 1 34 ? 61.972 58.986 8.328 1.00 40.95 ? 70 TYR A CE2 1 ATOM 275 C CZ . TYR A 1 34 ? 61.755 58.172 9.421 1.00 40.70 ? 70 TYR A CZ 1 ATOM 276 O OH . TYR A 1 34 ? 62.822 57.500 9.983 1.00 41.31 ? 70 TYR A OH 1 ATOM 277 N N . LYS A 1 35 ? 59.503 62.525 9.926 1.00 38.84 ? 71 LYS A N 1 ATOM 278 C CA . LYS A 1 35 ? 60.552 63.480 10.274 1.00 44.98 ? 71 LYS A CA 1 ATOM 279 C C . LYS A 1 35 ? 61.947 62.862 10.121 1.00 48.36 ? 71 LYS A C 1 ATOM 280 O O . LYS A 1 35 ? 62.212 61.790 10.660 1.00 45.56 ? 71 LYS A O 1 ATOM 281 C CB . LYS A 1 35 ? 60.343 64.007 11.699 1.00 49.90 ? 71 LYS A CB 1 ATOM 282 C CG . LYS A 1 35 ? 61.416 64.975 12.185 1.00 54.17 ? 71 LYS A CG 1 ATOM 283 N N . GLN A 1 36 ? 62.823 63.544 9.379 1.00 52.02 ? 72 GLN A N 1 ATOM 284 C CA . GLN A 1 36 ? 64.217 63.120 9.194 1.00 58.03 ? 72 GLN A CA 1 ATOM 285 C C . GLN A 1 36 ? 65.202 64.307 9.289 1.00 59.52 ? 72 GLN A C 1 ATOM 286 O O . GLN A 1 36 ? 65.129 65.236 8.483 1.00 56.88 ? 72 GLN A O 1 ATOM 287 C CB . GLN A 1 36 ? 64.377 62.417 7.847 1.00 56.41 ? 72 GLN A CB 1 ATOM 288 C CG . GLN A 1 36 ? 65.332 61.239 7.885 1.00 59.14 ? 72 GLN A CG 1 ATOM 289 C CD . GLN A 1 36 ? 65.676 60.739 6.504 1.00 67.21 ? 72 GLN A CD 1 ATOM 290 O OE1 . GLN A 1 36 ? 65.653 61.500 5.533 1.00 68.79 ? 72 GLN A OE1 1 ATOM 291 N NE2 . GLN A 1 36 ? 65.996 59.451 6.401 1.00 71.92 ? 72 GLN A NE2 1 ATOM 292 N N . GLU A 1 37 ? 66.140 64.238 10.241 1.00 63.07 ? 73 GLU A N 1 ATOM 293 C CA . GLU A 1 37 ? 66.940 65.396 10.697 1.00 63.34 ? 73 GLU A CA 1 ATOM 294 C C . GLU A 1 37 ? 66.051 66.590 11.014 1.00 61.13 ? 73 GLU A C 1 ATOM 295 O O . GLU A 1 37 ? 66.340 67.721 10.608 1.00 60.86 ? 73 GLU A O 1 ATOM 296 C CB . GLU A 1 37 ? 68.054 65.834 9.718 1.00 66.26 ? 73 GLU A CB 1 ATOM 297 C CG . GLU A 1 37 ? 69.057 66.856 10.369 1.00 70.84 ? 73 GLU A CG 1 ATOM 298 C CD . GLU A 1 37 ? 69.698 67.878 9.399 1.00 77.90 ? 73 GLU A CD 1 ATOM 299 O OE1 . GLU A 1 37 ? 69.097 68.220 8.348 1.00 72.77 ? 73 GLU A OE1 1 ATOM 300 O OE2 . GLU A 1 37 ? 70.820 68.352 9.706 1.00 76.91 ? 73 GLU A OE2 1 ATOM 301 N N . ASN A 1 38 ? 64.967 66.339 11.736 1.00 57.52 ? 74 ASN A N 1 ATOM 302 C CA . ASN A 1 38 ? 64.031 67.405 12.050 1.00 59.10 ? 74 ASN A CA 1 ATOM 303 C C . ASN A 1 38 ? 63.476 68.104 10.808 1.00 54.87 ? 74 ASN A C 1 ATOM 304 O O . ASN A 1 38 ? 62.878 69.176 10.900 1.00 55.89 ? 74 ASN A O 1 ATOM 305 C CB . ASN A 1 38 ? 64.685 68.399 12.999 1.00 63.68 ? 74 ASN A CB 1 ATOM 306 C CG . ASN A 1 38 ? 65.076 67.755 14.305 1.00 67.88 ? 74 ASN A CG 1 ATOM 307 O OD1 . ASN A 1 38 ? 66.139 67.131 14.415 1.00 66.20 ? 74 ASN A OD1 1 ATOM 308 N ND2 . ASN A 1 38 ? 64.202 67.871 15.302 1.00 73.19 ? 74 ASN A ND2 1 ATOM 309 N N . ASN A 1 39 ? 63.685 67.487 9.647 1.00 53.85 ? 75 ASN A N 1 ATOM 310 C CA . ASN A 1 39 ? 62.972 67.865 8.437 1.00 50.11 ? 75 ASN A CA 1 ATOM 311 C C . ASN A 1 39 ? 61.687 67.057 8.344 1.00 44.33 ? 75 ASN A C 1 ATOM 312 O O . ASN A 1 39 ? 61.685 65.847 8.532 1.00 43.61 ? 75 ASN A O 1 ATOM 313 C CB . ASN A 1 39 ? 63.818 67.605 7.189 1.00 47.30 ? 75 ASN A CB 1 ATOM 314 C CG . ASN A 1 39 ? 65.079 68.434 7.156 1.00 54.40 ? 75 ASN A CG 1 ATOM 315 O OD1 . ASN A 1 39 ? 65.022 69.659 7.074 1.00 53.87 ? 75 ASN A OD1 1 ATOM 316 N ND2 . ASN A 1 39 ? 66.230 67.770 7.205 1.00 56.86 ? 75 ASN A ND2 1 ATOM 317 N N . ILE A 1 40 ? 60.587 67.724 8.055 1.00 38.59 ? 76 ILE A N 1 ATOM 318 C CA . ILE A 1 40 ? 59.355 67.001 7.848 1.00 38.71 ? 76 ILE A CA 1 ATOM 319 C C . ILE A 1 40 ? 59.220 66.685 6.363 1.00 36.04 ? 76 ILE A C 1 ATOM 320 O O . ILE A 1 40 ? 59.140 67.589 5.529 1.00 39.08 ? 76 ILE A O 1 ATOM 321 C CB . ILE A 1 40 ? 58.154 67.792 8.389 1.00 38.78 ? 76 ILE A CB 1 ATOM 322 C CG1 . ILE A 1 40 ? 58.345 68.038 9.890 1.00 42.08 ? 76 ILE A CG1 1 ATOM 323 C CG2 . ILE A 1 40 ? 56.859 67.050 8.124 1.00 36.98 ? 76 ILE A CG2 1 ATOM 324 C CD1 . ILE A 1 40 ? 57.229 68.827 10.518 1.00 48.35 ? 76 ILE A CD1 1 ATOM 325 N N . LEU A 1 41 ? 59.246 65.396 6.040 1.00 36.53 ? 77 LEU A N 1 ATOM 326 C CA . LEU A 1 41 ? 59.110 64.948 4.662 1.00 33.98 ? 77 LEU A CA 1 ATOM 327 C C . LEU A 1 41 ? 57.737 64.338 4.468 1.00 35.46 ? 77 LEU A C 1 ATOM 328 O O . LEU A 1 41 ? 57.188 63.719 5.381 1.00 34.84 ? 77 LEU A O 1 ATOM 329 C CB . LEU A 1 41 ? 60.170 63.902 4.325 1.00 34.72 ? 77 LEU A CB 1 ATOM 330 C CG . LEU A 1 41 ? 61.642 64.158 4.643 1.00 39.86 ? 77 LEU A CG 1 ATOM 331 C CD1 . LEU A 1 41 ? 62.501 63.053 4.020 1.00 42.21 ? 77 LEU A CD1 1 ATOM 332 C CD2 . LEU A 1 41 ? 62.072 65.513 4.131 1.00 45.66 ? 77 LEU A CD2 1 ATOM 333 N N . VAL A 1 42 ? 57.173 64.530 3.283 1.00 34.13 ? 78 VAL A N 1 ATOM 334 C CA . VAL A 1 42 ? 55.977 63.801 2.889 1.00 33.21 ? 78 VAL A CA 1 ATOM 335 C C . VAL A 1 42 ? 56.395 62.725 1.886 1.00 33.15 ? 78 VAL A C 1 ATOM 336 O O . VAL A 1 42 ? 57.192 62.989 0.973 1.00 33.16 ? 78 VAL A O 1 ATOM 337 C CB . VAL A 1 42 ? 54.888 64.739 2.307 1.00 35.81 ? 78 VAL A CB 1 ATOM 338 C CG1 . VAL A 1 42 ? 55.519 65.816 1.481 1.00 40.01 ? 78 VAL A CG1 1 ATOM 339 C CG2 . VAL A 1 42 ? 53.867 63.956 1.479 1.00 33.73 ? 78 VAL A CG2 1 ATOM 340 N N . PHE A 1 43 ? 55.881 61.516 2.096 1.00 28.98 ? 79 PHE A N 1 ATOM 341 C CA . PHE A 1 43 ? 56.224 60.338 1.304 1.00 30.98 ? 79 PHE A CA 1 ATOM 342 C C . PHE A 1 43 ? 55.002 59.852 0.540 1.00 32.93 ? 79 PHE A C 1 ATOM 343 O O . PHE A 1 43 ? 53.891 59.841 1.068 1.00 33.23 ? 79 PHE A O 1 ATOM 344 C CB . PHE A 1 43 ? 56.683 59.199 2.213 1.00 30.12 ? 79 PHE A CB 1 ATOM 345 C CG . PHE A 1 43 ? 58.118 59.282 2.627 1.00 33.63 ? 79 PHE A CG 1 ATOM 346 C CD1 . PHE A 1 43 ? 58.520 60.163 3.626 1.00 30.35 ? 79 PHE A CD1 1 ATOM 347 C CD2 . PHE A 1 43 ? 59.070 58.464 2.034 1.00 35.08 ? 79 PHE A CD2 1 ATOM 348 C CE1 . PHE A 1 43 ? 59.846 60.228 4.019 1.00 34.17 ? 79 PHE A CE1 1 ATOM 349 C CE2 . PHE A 1 43 ? 60.407 58.530 2.425 1.00 35.25 ? 79 PHE A CE2 1 ATOM 350 C CZ . PHE A 1 43 ? 60.791 59.411 3.416 1.00 32.17 ? 79 PHE A CZ 1 ATOM 351 N N . ASN A 1 44 ? 55.211 59.450 -0.707 1.00 32.48 ? 80 ASN A N 1 ATOM 352 C CA . ASN A 1 44 ? 54.160 58.848 -1.511 1.00 29.30 ? 80 ASN A CA 1 ATOM 353 C C . ASN A 1 44 ? 54.243 57.328 -1.327 1.00 31.49 ? 80 ASN A C 1 ATOM 354 O O . ASN A 1 44 ? 55.283 56.728 -1.592 1.00 29.23 ? 80 ASN A O 1 ATOM 355 C CB . ASN A 1 44 ? 54.368 59.252 -2.971 1.00 32.24 ? 80 ASN A CB 1 ATOM 356 C CG . ASN A 1 44 ? 53.375 58.619 -3.901 1.00 32.24 ? 80 ASN A CG 1 ATOM 357 O OD1 . ASN A 1 44 ? 53.384 57.407 -4.087 1.00 32.16 ? 80 ASN A OD1 1 ATOM 358 N ND2 . ASN A 1 44 ? 52.518 59.440 -4.519 1.00 31.90 ? 80 ASN A ND2 1 ATOM 359 N N . ALA A 1 45 ? 53.174 56.699 -0.849 1.00 30.31 ? 81 ALA A N 1 ATOM 360 C CA . ALA A 1 45 ? 53.265 55.290 -0.430 1.00 29.88 ? 81 ALA A CA 1 ATOM 361 C C . ALA A 1 45 ? 53.462 54.314 -1.591 1.00 30.96 ? 81 ALA A C 1 ATOM 362 O O . ALA A 1 45 ? 54.232 53.353 -1.486 1.00 27.76 ? 81 ALA A O 1 ATOM 363 C CB . ALA A 1 45 ? 52.042 54.886 0.396 1.00 29.87 ? 81 ALA A CB 1 ATOM 364 N N . GLU A 1 46 ? 52.764 54.566 -2.696 1.00 31.51 ? 82 GLU A N 1 ATOM 365 C CA . GLU A 1 46 ? 52.803 53.677 -3.848 1.00 32.58 ? 82 GLU A CA 1 ATOM 366 C C . GLU A 1 46 ? 54.197 53.614 -4.466 1.00 32.27 ? 82 GLU A C 1 ATOM 367 O O . GLU A 1 46 ? 54.722 52.526 -4.708 1.00 32.74 ? 82 GLU A O 1 ATOM 368 C CB . GLU A 1 46 ? 51.774 54.116 -4.900 1.00 33.69 ? 82 GLU A CB 1 ATOM 369 C CG . GLU A 1 46 ? 51.782 53.286 -6.184 1.00 33.45 ? 82 GLU A CG 1 ATOM 370 C CD . GLU A 1 46 ? 51.366 51.835 -5.985 1.00 41.08 ? 82 GLU A CD 1 ATOM 371 O OE1 . GLU A 1 46 ? 50.700 51.521 -4.973 1.00 48.35 ? 82 GLU A OE1 1 ATOM 372 O OE2 . GLU A 1 46 ? 51.706 50.995 -6.847 1.00 50.72 ? 82 GLU A OE2 1 ATOM 373 N N . TYR A 1 47 ? 54.799 54.778 -4.699 1.00 29.29 ? 83 TYR A N 1 ATOM 374 C CA . TYR A 1 47 ? 56.055 54.856 -5.436 1.00 29.35 ? 83 TYR A CA 1 ATOM 375 C C . TYR A 1 47 ? 57.289 55.056 -4.551 1.00 33.71 ? 83 TYR A C 1 ATOM 376 O O . TYR A 1 47 ? 58.416 54.789 -4.972 1.00 32.18 ? 83 TYR A O 1 ATOM 377 C CB . TYR A 1 47 ? 55.960 55.954 -6.507 1.00 31.61 ? 83 TYR A CB 1 ATOM 378 C CG . TYR A 1 47 ? 54.804 55.733 -7.479 1.00 28.23 ? 83 TYR A CG 1 ATOM 379 C CD1 . TYR A 1 47 ? 54.881 54.754 -8.466 1.00 29.79 ? 83 TYR A CD1 1 ATOM 380 C CD2 . TYR A 1 47 ? 53.641 56.492 -7.399 1.00 30.70 ? 83 TYR A CD2 1 ATOM 381 C CE1 . TYR A 1 47 ? 53.843 54.530 -9.348 1.00 28.97 ? 83 TYR A CE1 1 ATOM 382 C CE2 . TYR A 1 47 ? 52.589 56.285 -8.284 1.00 28.35 ? 83 TYR A CE2 1 ATOM 383 C CZ . TYR A 1 47 ? 52.704 55.294 -9.256 1.00 33.41 ? 83 TYR A CZ 1 ATOM 384 O OH . TYR A 1 47 ? 51.685 55.068 -10.136 1.00 29.60 ? 83 TYR A OH 1 ATOM 385 N N . GLY A 1 48 ? 57.080 55.531 -3.327 1.00 29.36 ? 84 GLY A N 1 ATOM 386 C CA . GLY A 1 48 ? 58.184 55.709 -2.399 1.00 30.92 ? 84 GLY A CA 1 ATOM 387 C C . GLY A 1 48 ? 58.934 57.026 -2.526 1.00 34.79 ? 84 GLY A C 1 ATOM 388 O O . GLY A 1 48 ? 59.847 57.290 -1.741 1.00 32.17 ? 84 GLY A O 1 ATOM 389 N N . ASN A 1 49 ? 58.566 57.857 -3.504 1.00 29.37 ? 85 ASN A N 1 ATOM 390 C CA . ASN A 1 49 ? 59.207 59.161 -3.619 1.00 29.37 ? 85 ASN A CA 1 ATOM 391 C C . ASN A 1 49 ? 58.764 60.123 -2.509 1.00 34.35 ? 85 ASN A C 1 ATOM 392 O O . ASN A 1 49 ? 57.655 60.011 -1.987 1.00 31.81 ? 85 ASN A O 1 ATOM 393 C CB . ASN A 1 49 ? 59.036 59.760 -5.024 1.00 30.46 ? 85 ASN A CB 1 ATOM 394 C CG . ASN A 1 49 ? 57.636 60.265 -5.299 1.00 31.05 ? 85 ASN A CG 1 ATOM 395 O OD1 . ASN A 1 49 ? 56.668 59.499 -5.315 1.00 29.33 ? 85 ASN A OD1 1 ATOM 396 N ND2 . ASN A 1 49 ? 57.530 61.569 -5.546 1.00 33.20 ? 85 ASN A ND2 1 ATOM 397 N N . SER A 1 50 ? 59.651 61.039 -2.138 1.00 32.57 ? 86 SER A N 1 ATOM 398 C CA . SER A 1 50 ? 59.398 61.971 -1.054 1.00 33.73 ? 86 SER A CA 1 ATOM 399 C C . SER A 1 50 ? 59.914 63.364 -1.403 1.00 36.70 ? 86 SER A C 1 ATOM 400 O O . SER A 1 50 ? 60.647 63.543 -2.376 1.00 37.82 ? 86 SER A O 1 ATOM 401 C CB . SER A 1 50 ? 60.055 61.471 0.239 1.00 33.93 ? 86 SER A CB 1 ATOM 402 O OG . SER A 1 50 ? 61.460 61.337 0.092 1.00 33.62 ? 86 SER A OG 1 ATOM 403 N N . SER A 1 51 ? 59.517 64.350 -0.612 1.00 33.23 ? 87 SER A N 1 ATOM 404 C CA . SER A 1 51 ? 60.056 65.702 -0.728 1.00 33.83 ? 87 SER A CA 1 ATOM 405 C C . SER A 1 51 ? 59.962 66.386 0.631 1.00 38.35 ? 87 SER A C 1 ATOM 406 O O . SER A 1 51 ? 59.183 65.968 1.487 1.00 34.90 ? 87 SER A O 1 ATOM 407 C CB . SER A 1 51 ? 59.342 66.513 -1.819 1.00 39.34 ? 87 SER A CB 1 ATOM 408 O OG . SER A 1 51 ? 57.944 66.290 -1.825 1.00 42.11 ? 87 SER A OG 1 ATOM 409 N N . VAL A 1 52 ? 60.773 67.409 0.853 1.00 32.47 ? 88 VAL A N 1 ATOM 410 C CA . VAL A 1 52 ? 60.763 68.052 2.152 1.00 39.11 ? 88 VAL A CA 1 ATOM 411 C C . VAL A 1 52 ? 59.578 69.006 2.236 1.00 42.84 ? 88 VAL A C 1 ATOM 412 O O . VAL A 1 52 ? 59.418 69.901 1.406 1.00 44.17 ? 88 VAL A O 1 ATOM 413 C CB . VAL A 1 52 ? 62.101 68.753 2.483 1.00 42.23 ? 88 VAL A CB 1 ATOM 414 C CG1 . VAL A 1 52 ? 62.558 69.602 1.323 1.00 47.73 ? 88 VAL A CG1 1 ATOM 415 C CG2 . VAL A 1 52 ? 61.967 69.584 3.758 1.00 41.57 ? 88 VAL A CG2 1 ATOM 416 N N . PHE A 1 53 ? 58.731 68.774 3.229 1.00 40.58 ? 89 PHE A N 1 ATOM 417 C CA . PHE A 1 53 ? 57.568 69.611 3.470 1.00 40.86 ? 89 PHE A CA 1 ATOM 418 C C . PHE A 1 53 ? 57.940 70.837 4.299 1.00 44.66 ? 89 PHE A C 1 ATOM 419 O O . PHE A 1 53 ? 57.496 71.950 4.013 1.00 42.16 ? 89 PHE A O 1 ATOM 420 C CB . PHE A 1 53 ? 56.485 68.809 4.191 1.00 40.99 ? 89 PHE A CB 1 ATOM 421 C CG . PHE A 1 53 ? 55.211 69.567 4.379 1.00 46.16 ? 89 PHE A CG 1 ATOM 422 C CD1 . PHE A 1 53 ? 54.565 70.127 3.291 1.00 52.32 ? 89 PHE A CD1 1 ATOM 423 C CD2 . PHE A 1 53 ? 54.668 69.739 5.638 1.00 44.20 ? 89 PHE A CD2 1 ATOM 424 C CE1 . PHE A 1 53 ? 53.397 70.834 3.459 1.00 56.04 ? 89 PHE A CE1 1 ATOM 425 C CE2 . PHE A 1 53 ? 53.504 70.448 5.810 1.00 45.11 ? 89 PHE A CE2 1 ATOM 426 C CZ . PHE A 1 53 ? 52.867 70.993 4.723 1.00 49.56 ? 89 PHE A CZ 1 ATOM 427 N N . LEU A 1 54 ? 58.761 70.623 5.323 1.00 41.57 ? 90 LEU A N 1 ATOM 428 C CA . LEU A 1 54 ? 59.169 71.691 6.220 1.00 44.42 ? 90 LEU A CA 1 ATOM 429 C C . LEU A 1 54 ? 60.634 71.537 6.612 1.00 45.33 ? 90 LEU A C 1 ATOM 430 O O . LEU A 1 54 ? 61.009 70.538 7.239 1.00 41.64 ? 90 LEU A O 1 ATOM 431 C CB . LEU A 1 54 ? 58.297 71.661 7.470 1.00 44.52 ? 90 LEU A CB 1 ATOM 432 C CG . LEU A 1 54 ? 58.224 72.955 8.258 1.00 53.54 ? 90 LEU A CG 1 ATOM 433 C CD1 . LEU A 1 54 ? 57.668 74.064 7.376 1.00 52.41 ? 90 LEU A CD1 1 ATOM 434 C CD2 . LEU A 1 54 ? 57.362 72.739 9.490 1.00 55.64 ? 90 LEU A CD2 1 ATOM 435 N N . GLU A 1 55 ? 61.451 72.525 6.239 1.00 46.20 ? 91 GLU A N 1 ATOM 436 C CA . GLU A 1 55 ? 62.891 72.527 6.533 1.00 55.48 ? 91 GLU A CA 1 ATOM 437 C C . GLU A 1 55 ? 63.174 72.621 8.035 1.00 54.70 ? 91 GLU A C 1 ATOM 438 O O . GLU A 1 55 ? 62.472 73.328 8.763 1.00 52.12 ? 91 GLU A O 1 ATOM 439 C CB . GLU A 1 55 ? 63.600 73.690 5.818 1.00 56.68 ? 91 GLU A CB 1 ATOM 440 C CG . GLU A 1 55 ? 63.577 73.622 4.300 1.00 60.09 ? 91 GLU A CG 1 ATOM 441 N N . ASN A 1 56 ? 64.207 71.914 8.486 1.00 51.07 ? 92 ASN A N 1 ATOM 442 C CA . ASN A 1 56 ? 64.630 71.980 9.883 1.00 57.14 ? 92 ASN A CA 1 ATOM 443 C C . ASN A 1 56 ? 65.039 73.396 10.308 1.00 61.11 ? 92 ASN A C 1 ATOM 444 O O . ASN A 1 56 ? 65.191 73.684 11.496 1.00 64.19 ? 92 ASN A O 1 ATOM 445 C CB . ASN A 1 56 ? 65.756 70.971 10.171 1.00 56.22 ? 92 ASN A CB 1 ATOM 446 C CG . ASN A 1 56 ? 66.970 71.150 9.257 1.00 57.23 ? 92 ASN A CG 1 ATOM 447 O OD1 . ASN A 1 56 ? 67.079 72.136 8.531 1.00 54.71 ? 92 ASN A OD1 1 ATOM 448 N ND2 . ASN A 1 56 ? 67.890 70.192 9.302 1.00 58.46 ? 92 ASN A ND2 1 ATOM 449 N N . SER A 1 57 ? 65.191 74.275 9.323 1.00 63.36 ? 93 SER A N 1 ATOM 450 C CA . SER A 1 57 ? 65.667 75.634 9.552 1.00 65.26 ? 93 SER A CA 1 ATOM 451 C C . SER A 1 57 ? 64.523 76.632 9.685 1.00 65.45 ? 93 SER A C 1 ATOM 452 O O . SER A 1 57 ? 64.739 77.781 10.067 1.00 69.64 ? 93 SER A O 1 ATOM 453 C CB . SER A 1 57 ? 66.575 76.067 8.395 1.00 66.15 ? 93 SER A CB 1 ATOM 454 O OG . SER A 1 57 ? 65.832 76.220 7.191 1.00 61.79 ? 93 SER A OG 1 ATOM 455 N N . THR A 1 58 ? 63.309 76.195 9.366 1.00 60.86 ? 94 THR A N 1 ATOM 456 C CA . THR A 1 58 ? 62.171 77.107 9.282 1.00 59.75 ? 94 THR A CA 1 ATOM 457 C C . THR A 1 58 ? 61.954 77.947 10.543 1.00 63.33 ? 94 THR A C 1 ATOM 458 O O . THR A 1 58 ? 61.628 79.135 10.454 1.00 62.66 ? 94 THR A O 1 ATOM 459 C CB . THR A 1 58 ? 60.870 76.359 8.948 1.00 58.48 ? 94 THR A CB 1 ATOM 460 O OG1 . THR A 1 58 ? 61.050 75.613 7.738 1.00 60.49 ? 94 THR A OG1 1 ATOM 461 C CG2 . THR A 1 58 ? 59.709 77.343 8.770 1.00 55.97 ? 94 THR A CG2 1 ATOM 462 N N . PHE A 1 59 ? 62.140 77.342 11.714 1.00 62.55 ? 95 PHE A N 1 ATOM 463 C CA . PHE A 1 59 ? 61.776 78.021 12.956 1.00 65.07 ? 95 PHE A CA 1 ATOM 464 C C . PHE A 1 59 ? 62.964 78.404 13.837 1.00 70.36 ? 95 PHE A C 1 ATOM 465 O O . PHE A 1 59 ? 62.800 78.657 15.033 1.00 69.58 ? 95 PHE A O 1 ATOM 466 C CB . PHE A 1 59 ? 60.771 77.175 13.747 1.00 61.42 ? 95 PHE A CB 1 ATOM 467 C CG . PHE A 1 59 ? 59.535 76.825 12.968 1.00 56.60 ? 95 PHE A CG 1 ATOM 468 C CD1 . PHE A 1 59 ? 58.635 77.812 12.598 1.00 54.65 ? 95 PHE A CD1 1 ATOM 469 C CD2 . PHE A 1 59 ? 59.279 75.513 12.597 1.00 56.65 ? 95 PHE A CD2 1 ATOM 470 C CE1 . PHE A 1 59 ? 57.502 77.495 11.874 1.00 55.40 ? 95 PHE A CE1 1 ATOM 471 C CE2 . PHE A 1 59 ? 58.143 75.189 11.871 1.00 50.69 ? 95 PHE A CE2 1 ATOM 472 C CZ . PHE A 1 59 ? 57.255 76.180 11.513 1.00 53.19 ? 95 PHE A CZ 1 ATOM 473 N N . ASP A 1 60 ? 64.156 78.460 13.248 1.00 70.51 ? 96 ASP A N 1 ATOM 474 C CA . ASP A 1 60 ? 65.360 78.770 14.017 1.00 72.60 ? 96 ASP A CA 1 ATOM 475 C C . ASP A 1 60 ? 65.223 80.061 14.832 1.00 73.94 ? 96 ASP A C 1 ATOM 476 O O . ASP A 1 60 ? 65.730 80.154 15.951 1.00 73.10 ? 96 ASP A O 1 ATOM 477 C CB . ASP A 1 60 ? 66.595 78.830 13.112 1.00 75.15 ? 96 ASP A CB 1 ATOM 478 C CG . ASP A 1 60 ? 67.071 77.450 12.678 1.00 78.22 ? 96 ASP A CG 1 ATOM 479 O OD1 . ASP A 1 60 ? 66.469 76.442 13.118 1.00 76.41 ? 96 ASP A OD1 1 ATOM 480 O OD2 . ASP A 1 60 ? 68.056 77.374 11.909 1.00 77.65 ? 96 ASP A OD2 1 ATOM 481 N N . GLU A 1 61 ? 64.528 81.047 14.276 1.00 71.45 ? 97 GLU A N 1 ATOM 482 C CA . GLU A 1 61 ? 64.355 82.325 14.962 1.00 73.57 ? 97 GLU A CA 1 ATOM 483 C C . GLU A 1 61 ? 63.043 82.396 15.749 1.00 71.19 ? 97 GLU A C 1 ATOM 484 O O . GLU A 1 61 ? 62.527 83.486 16.007 1.00 70.98 ? 97 GLU A O 1 ATOM 485 C CB . GLU A 1 61 ? 64.441 83.486 13.962 1.00 77.56 ? 97 GLU A CB 1 ATOM 486 C CG . GLU A 1 61 ? 65.778 83.581 13.221 1.00 79.78 ? 97 GLU A CG 1 ATOM 487 C CD . GLU A 1 61 ? 66.957 83.826 14.156 1.00 86.76 ? 97 GLU A CD 1 ATOM 488 O OE1 . GLU A 1 61 ? 66.973 84.875 14.840 1.00 87.15 ? 97 GLU A OE1 1 ATOM 489 O OE2 . GLU A 1 61 ? 67.868 82.967 14.209 1.00 86.01 ? 97 GLU A OE2 1 ATOM 490 N N . PHE A 1 62 ? 62.518 81.235 16.140 1.00 66.33 ? 98 PHE A N 1 ATOM 491 C CA . PHE A 1 62 ? 61.223 81.163 16.815 1.00 61.11 ? 98 PHE A CA 1 ATOM 492 C C . PHE A 1 62 ? 61.268 81.746 18.227 1.00 64.08 ? 98 PHE A C 1 ATOM 493 O O . PHE A 1 62 ? 60.314 82.386 18.675 1.00 63.13 ? 98 PHE A O 1 ATOM 494 C CB . PHE A 1 62 ? 60.712 79.721 16.847 1.00 63.81 ? 98 PHE A CB 1 ATOM 495 C CG . PHE A 1 62 ? 59.307 79.580 17.375 1.00 61.08 ? 98 PHE A CG 1 ATOM 496 C CD1 . PHE A 1 62 ? 58.227 80.047 16.646 1.00 59.66 ? 98 PHE A CD1 1 ATOM 497 C CD2 . PHE A 1 62 ? 59.067 78.964 18.593 1.00 59.90 ? 98 PHE A CD2 1 ATOM 498 C CE1 . PHE A 1 62 ? 56.933 79.916 17.125 1.00 55.80 ? 98 PHE A CE1 1 ATOM 499 C CE2 . PHE A 1 62 ? 57.773 78.832 19.078 1.00 54.31 ? 98 PHE A CE2 1 ATOM 500 C CZ . PHE A 1 62 ? 56.706 79.307 18.337 1.00 51.21 ? 98 PHE A CZ 1 ATOM 501 N N . GLY A 1 63 ? 62.374 81.525 18.931 1.00 63.26 ? 99 GLY A N 1 ATOM 502 C CA . GLY A 1 63 ? 62.543 82.102 20.253 1.00 62.19 ? 99 GLY A CA 1 ATOM 503 C C . GLY A 1 63 ? 62.032 81.220 21.377 1.00 62.26 ? 99 GLY A C 1 ATOM 504 O O . GLY A 1 63 ? 62.146 81.568 22.554 1.00 62.58 ? 99 GLY A O 1 ATOM 505 N N . HIS A 1 64 ? 61.458 80.078 21.016 1.00 59.13 ? 100 HIS A N 1 ATOM 506 C CA . HIS A 1 64 ? 61.070 79.076 22.003 1.00 57.46 ? 100 HIS A CA 1 ATOM 507 C C . HIS A 1 64 ? 61.390 77.695 21.463 1.00 56.34 ? 100 HIS A C 1 ATOM 508 O O . HIS A 1 64 ? 61.274 77.449 20.261 1.00 54.88 ? 100 HIS A O 1 ATOM 509 C CB . HIS A 1 64 ? 59.578 79.165 22.311 1.00 54.09 ? 100 HIS A CB 1 ATOM 510 C CG . HIS A 1 64 ? 59.178 80.428 23.006 1.00 56.91 ? 100 HIS A CG 1 ATOM 511 N ND1 . HIS A 1 64 ? 58.392 81.391 22.408 1.00 57.47 ? 100 HIS A ND1 1 ATOM 512 C CD2 . HIS A 1 64 ? 59.451 80.884 24.253 1.00 55.06 ? 100 HIS A CD2 1 ATOM 513 C CE1 . HIS A 1 64 ? 58.201 82.388 23.255 1.00 58.22 ? 100 HIS A CE1 1 ATOM 514 N NE2 . HIS A 1 64 ? 58.830 82.102 24.383 1.00 56.94 ? 100 HIS A NE2 1 ATOM 515 N N . SER A 1 65 ? 61.794 76.796 22.350 1.00 54.03 ? 101 SER A N 1 ATOM 516 C CA . SER A 1 65 ? 62.031 75.414 21.960 1.00 52.65 ? 101 SER A CA 1 ATOM 517 C C . SER A 1 65 ? 60.697 74.747 21.620 1.00 51.33 ? 101 SER A C 1 ATOM 518 O O . SER A 1 65 ? 59.790 74.708 22.452 1.00 48.58 ? 101 SER A O 1 ATOM 519 C CB . SER A 1 65 ? 62.733 74.660 23.092 1.00 57.63 ? 101 SER A CB 1 ATOM 520 O OG . SER A 1 65 ? 63.337 73.466 22.616 1.00 59.81 ? 101 SER A OG 1 ATOM 521 N N . ILE A 1 66 ? 60.577 74.236 20.397 1.00 45.83 ? 102 ILE A N 1 ATOM 522 C CA . ILE A 1 66 ? 59.335 73.614 19.944 1.00 46.61 ? 102 ILE A CA 1 ATOM 523 C C . ILE A 1 66 ? 59.219 72.164 20.414 1.00 48.25 ? 102 ILE A C 1 ATOM 524 O O . ILE A 1 66 ? 60.093 71.342 20.143 1.00 50.55 ? 102 ILE A O 1 ATOM 525 C CB . ILE A 1 66 ? 59.192 73.698 18.419 1.00 44.99 ? 102 ILE A CB 1 ATOM 526 C CG1 . ILE A 1 66 ? 58.915 75.145 18.007 1.00 49.39 ? 102 ILE A CG1 1 ATOM 527 C CG2 . ILE A 1 66 ? 58.073 72.798 17.939 1.00 44.13 ? 102 ILE A CG2 1 ATOM 528 C CD1 . ILE A 1 66 ? 59.017 75.393 16.517 1.00 55.07 ? 102 ILE A CD1 1 ATOM 529 N N . ASN A 1 67 ? 58.132 71.866 21.122 1.00 46.02 ? 103 ASN A N 1 ATOM 530 C CA . ASN A 1 67 ? 57.939 70.568 21.767 1.00 47.43 ? 103 ASN A CA 1 ATOM 531 C C . ASN A 1 67 ? 57.329 69.537 20.824 1.00 45.52 ? 103 ASN A C 1 ATOM 532 O O . ASN A 1 67 ? 57.710 68.367 20.817 1.00 44.68 ? 103 ASN A O 1 ATOM 533 C CB . ASN A 1 67 ? 57.061 70.730 23.018 1.00 45.54 ? 103 ASN A CB 1 ATOM 534 C CG . ASN A 1 67 ? 56.838 69.423 23.751 1.00 49.36 ? 103 ASN A CG 1 ATOM 535 O OD1 . ASN A 1 67 ? 55.776 68.802 23.638 1.00 48.55 ? 103 ASN A OD1 1 ATOM 536 N ND2 . ASN A 1 67 ? 57.841 68.997 24.513 1.00 46.87 ? 103 ASN A ND2 1 ATOM 537 N N . ASP A 1 68 ? 56.374 69.987 20.026 1.00 41.98 ? 104 ASP A N 1 ATOM 538 C CA . ASP A 1 68 ? 55.724 69.130 19.056 1.00 43.49 ? 104 ASP A CA 1 ATOM 539 C C . ASP A 1 68 ? 54.974 70.057 18.106 1.00 44.00 ? 104 ASP A C 1 ATOM 540 O O . ASP A 1 68 ? 54.842 71.257 18.374 1.00 39.58 ? 104 ASP A O 1 ATOM 541 C CB . ASP A 1 68 ? 54.771 68.151 19.754 1.00 44.77 ? 104 ASP A CB 1 ATOM 542 C CG . ASP A 1 68 ? 54.489 66.900 18.924 1.00 48.36 ? 104 ASP A CG 1 ATOM 543 O OD1 . ASP A 1 68 ? 54.807 66.882 17.715 1.00 50.70 ? 104 ASP A OD1 1 ATOM 544 O OD2 . ASP A 1 68 ? 53.933 65.928 19.483 1.00 50.71 ? 104 ASP A OD2 1 ATOM 545 N N . TYR A 1 69 ? 54.510 69.504 16.991 1.00 40.27 ? 105 TYR A N 1 ATOM 546 C CA . TYR A 1 69 ? 53.816 70.264 15.976 1.00 39.48 ? 105 TYR A CA 1 ATOM 547 C C . TYR A 1 69 ? 52.595 69.452 15.584 1.00 41.99 ? 105 TYR A C 1 ATOM 548 O O . TYR A 1 69 ? 52.529 68.250 15.847 1.00 43.88 ? 105 TYR A O 1 ATOM 549 C CB . TYR A 1 69 ? 54.727 70.464 14.757 1.00 41.74 ? 105 TYR A CB 1 ATOM 550 C CG . TYR A 1 69 ? 55.068 69.158 14.050 1.00 43.22 ? 105 TYR A CG 1 ATOM 551 C CD1 . TYR A 1 69 ? 54.259 68.658 13.028 1.00 44.99 ? 105 TYR A CD1 1 ATOM 552 C CD2 . TYR A 1 69 ? 56.182 68.412 14.424 1.00 44.76 ? 105 TYR A CD2 1 ATOM 553 C CE1 . TYR A 1 69 ? 54.566 67.445 12.387 1.00 47.75 ? 105 TYR A CE1 1 ATOM 554 C CE2 . TYR A 1 69 ? 56.496 67.202 13.795 1.00 47.34 ? 105 TYR A CE2 1 ATOM 555 C CZ . TYR A 1 69 ? 55.688 66.725 12.782 1.00 51.35 ? 105 TYR A CZ 1 ATOM 556 O OH . TYR A 1 69 ? 56.012 65.526 12.167 1.00 58.22 ? 105 TYR A OH 1 ATOM 557 N N . SER A 1 70 ? 51.622 70.100 14.961 1.00 36.42 ? 106 SER A N 1 ATOM 558 C CA . SER A 1 70 ? 50.461 69.392 14.458 1.00 35.39 ? 106 SER A CA 1 ATOM 559 C C . SER A 1 70 ? 49.968 70.102 13.224 1.00 37.13 ? 106 SER A C 1 ATOM 560 O O . SER A 1 70 ? 49.486 71.222 13.300 1.00 34.52 ? 106 SER A O 1 ATOM 561 C CB . SER A 1 70 ? 49.343 69.338 15.497 1.00 37.53 ? 106 SER A CB 1 ATOM 562 O OG . SER A 1 70 ? 48.143 68.863 14.904 1.00 37.71 ? 106 SER A OG 1 ATOM 563 N N . ILE A 1 71 ? 50.084 69.450 12.077 1.00 36.48 ? 107 ILE A N 1 ATOM 564 C CA . ILE A 1 71 ? 49.677 70.081 10.835 1.00 36.26 ? 107 ILE A CA 1 ATOM 565 C C . ILE A 1 71 ? 48.180 69.907 10.628 1.00 36.46 ? 107 ILE A C 1 ATOM 566 O O . ILE A 1 71 ? 47.629 68.853 10.933 1.00 33.06 ? 107 ILE A O 1 ATOM 567 C CB . ILE A 1 71 ? 50.491 69.522 9.646 1.00 36.20 ? 107 ILE A CB 1 ATOM 568 C CG1 . ILE A 1 71 ? 51.968 69.860 9.856 1.00 37.61 ? 107 ILE A CG1 1 ATOM 569 C CG2 . ILE A 1 71 ? 49.997 70.110 8.358 1.00 35.75 ? 107 ILE A CG2 1 ATOM 570 C CD1 . ILE A 1 71 ? 52.934 68.950 9.143 1.00 45.13 ? 107 ILE A CD1 1 ATOM 571 N N . SER A 1 72 ? 47.512 70.947 10.132 1.00 32.98 ? 108 SER A N 1 ATOM 572 C CA . SER A 1 72 ? 46.082 70.853 9.891 1.00 33.77 ? 108 SER A CA 1 ATOM 573 C C . SER A 1 72 ? 45.850 69.829 8.785 1.00 39.42 ? 108 SER A C 1 ATOM 574 O O . SER A 1 72 ? 46.766 69.538 8.020 1.00 39.44 ? 108 SER A O 1 ATOM 575 C CB . SER A 1 72 ? 45.522 72.211 9.495 1.00 33.44 ? 108 SER A CB 1 ATOM 576 O OG . SER A 1 72 ? 46.361 72.808 8.525 1.00 39.37 ? 108 SER A OG 1 ATOM 577 N N . PRO A 1 73 ? 44.629 69.275 8.712 1.00 37.92 ? 109 PRO A N 1 ATOM 578 C CA . PRO A 1 73 ? 44.256 68.202 7.782 1.00 36.06 ? 109 PRO A CA 1 ATOM 579 C C . PRO A 1 73 ? 44.405 68.615 6.327 1.00 43.22 ? 109 PRO A C 1 ATOM 580 O O . PRO A 1 73 ? 44.666 67.752 5.477 1.00 38.89 ? 109 PRO A O 1 ATOM 581 C CB . PRO A 1 73 ? 42.768 67.975 8.080 1.00 39.12 ? 109 PRO A CB 1 ATOM 582 C CG . PRO A 1 73 ? 42.581 68.466 9.477 1.00 37.66 ? 109 PRO A CG 1 ATOM 583 C CD . PRO A 1 73 ? 43.529 69.617 9.634 1.00 36.34 ? 109 PRO A CD 1 ATOM 584 N N . ASP A 1 74 ? 44.225 69.906 6.050 1.00 40.27 ? 110 ASP A N 1 ATOM 585 C CA . ASP A 1 74 ? 44.307 70.435 4.689 1.00 39.24 ? 110 ASP A CA 1 ATOM 586 C C . ASP A 1 74 ? 45.672 71.041 4.349 1.00 42.29 ? 110 ASP A C 1 ATOM 587 O O . ASP A 1 74 ? 45.807 71.769 3.364 1.00 48.19 ? 110 ASP A O 1 ATOM 588 C CB . ASP A 1 74 ? 43.192 71.457 4.441 1.00 41.88 ? 110 ASP A CB 1 ATOM 589 C CG . ASP A 1 74 ? 43.300 72.687 5.347 1.00 43.18 ? 110 ASP A CG 1 ATOM 590 O OD1 . ASP A 1 74 ? 44.172 72.712 6.242 1.00 43.97 ? 110 ASP A OD1 1 ATOM 591 O OD2 . ASP A 1 74 ? 42.500 73.629 5.168 1.00 44.50 ? 110 ASP A OD2 1 ATOM 592 N N . GLY A 1 75 ? 46.678 70.731 5.159 1.00 38.32 ? 111 GLY A N 1 ATOM 593 C CA . GLY A 1 75 ? 48.040 71.193 4.927 1.00 42.40 ? 111 GLY A CA 1 ATOM 594 C C . GLY A 1 75 ? 48.281 72.699 4.956 1.00 43.68 ? 111 GLY A C 1 ATOM 595 O O . GLY A 1 75 ? 49.382 73.153 4.643 1.00 43.04 ? 111 GLY A O 1 ATOM 596 N N . GLN A 1 76 ? 47.272 73.478 5.341 1.00 38.10 ? 112 GLN A N 1 ATOM 597 C CA . GLN A 1 76 ? 47.380 74.939 5.286 1.00 42.14 ? 112 GLN A CA 1 ATOM 598 C C . GLN A 1 76 ? 48.047 75.591 6.514 1.00 40.82 ? 112 GLN A C 1 ATOM 599 O O . GLN A 1 76 ? 48.653 76.661 6.406 1.00 41.57 ? 112 GLN A O 1 ATOM 600 C CB . GLN A 1 76 ? 46.006 75.566 5.014 1.00 41.16 ? 112 GLN A CB 1 ATOM 601 C CG . GLN A 1 76 ? 45.440 75.199 3.641 1.00 48.47 ? 112 GLN A CG 1 ATOM 602 C CD . GLN A 1 76 ? 44.129 75.898 3.334 1.00 51.82 ? 112 GLN A CD 1 ATOM 603 O OE1 . GLN A 1 76 ? 43.924 77.061 3.689 1.00 53.20 ? 112 GLN A OE1 1 ATOM 604 N NE2 . GLN A 1 76 ? 43.231 75.187 2.667 1.00 55.27 ? 112 GLN A NE2 1 ATOM 605 N N . PHE A 1 77 ? 47.934 74.957 7.676 1.00 41.31 ? 113 PHE A N 1 ATOM 606 C CA . PHE A 1 77 ? 48.472 75.543 8.903 1.00 39.51 ? 113 PHE A CA 1 ATOM 607 C C . PHE A 1 77 ? 49.220 74.505 9.719 1.00 38.16 ? 113 PHE A C 1 ATOM 608 O O . PHE A 1 77 ? 48.976 73.306 9.584 1.00 38.93 ? 113 PHE A O 1 ATOM 609 C CB . PHE A 1 77 ? 47.358 76.158 9.751 1.00 35.66 ? 113 PHE A CB 1 ATOM 610 C CG . PHE A 1 77 ? 46.581 77.236 9.051 1.00 39.46 ? 113 PHE A CG 1 ATOM 611 C CD1 . PHE A 1 77 ? 47.005 78.556 9.093 1.00 45.77 ? 113 PHE A CD1 1 ATOM 612 C CD2 . PHE A 1 77 ? 45.420 76.933 8.362 1.00 37.61 ? 113 PHE A CD2 1 ATOM 613 C CE1 . PHE A 1 77 ? 46.288 79.555 8.444 1.00 47.15 ? 113 PHE A CE1 1 ATOM 614 C CE2 . PHE A 1 77 ? 44.701 77.922 7.713 1.00 41.48 ? 113 PHE A CE2 1 ATOM 615 C CZ . PHE A 1 77 ? 45.132 79.237 7.757 1.00 40.45 ? 113 PHE A CZ 1 ATOM 616 N N . ILE A 1 78 ? 50.142 74.969 10.555 1.00 38.70 ? 114 ILE A N 1 ATOM 617 C CA . ILE A 1 78 ? 50.813 74.086 11.495 1.00 39.06 ? 114 ILE A CA 1 ATOM 618 C C . ILE A 1 78 ? 50.837 74.691 12.897 1.00 41.55 ? 114 ILE A C 1 ATOM 619 O O . ILE A 1 78 ? 51.322 75.810 13.093 1.00 41.73 ? 114 ILE A O 1 ATOM 620 C CB . ILE A 1 78 ? 52.244 73.742 11.046 1.00 41.67 ? 114 ILE A CB 1 ATOM 621 C CG1 . ILE A 1 78 ? 52.919 72.845 12.087 1.00 41.20 ? 114 ILE A CG1 1 ATOM 622 C CG2 . ILE A 1 78 ? 53.058 75.005 10.815 1.00 46.00 ? 114 ILE A CG2 1 ATOM 623 C CD1 . ILE A 1 78 ? 54.298 72.366 11.675 1.00 46.42 ? 114 ILE A CD1 1 ATOM 624 N N . LEU A 1 79 ? 50.299 73.944 13.859 1.00 40.45 ? 115 LEU A N 1 ATOM 625 C CA . LEU A 1 79 ? 50.334 74.309 15.273 1.00 36.84 ? 115 LEU A CA 1 ATOM 626 C C . LEU A 1 79 ? 51.698 73.993 15.879 1.00 38.58 ? 115 LEU A C 1 ATOM 627 O O . LEU A 1 79 ? 52.212 72.885 15.714 1.00 35.12 ? 115 LEU A O 1 ATOM 628 C CB . LEU A 1 79 ? 49.291 73.490 16.020 1.00 39.12 ? 115 LEU A CB 1 ATOM 629 C CG . LEU A 1 79 ? 48.041 74.144 16.577 1.00 39.90 ? 115 LEU A CG 1 ATOM 630 C CD1 . LEU A 1 79 ? 47.223 73.068 17.251 1.00 43.10 ? 115 LEU A CD1 1 ATOM 631 C CD2 . LEU A 1 79 ? 48.409 75.224 17.569 1.00 38.72 ? 115 LEU A CD2 1 ATOM 632 N N . LEU A 1 80 ? 52.268 74.949 16.606 1.00 37.67 ? 116 LEU A N 1 ATOM 633 C CA . LEU A 1 80 ? 53.530 74.740 17.306 1.00 36.61 ? 116 LEU A CA 1 ATOM 634 C C . LEU A 1 80 ? 53.345 74.729 18.826 1.00 39.01 ? 116 LEU A C 1 ATOM 635 O O . LEU A 1 80 ? 52.943 75.723 19.421 1.00 35.33 ? 116 LEU A O 1 ATOM 636 C CB . LEU A 1 80 ? 54.537 75.821 16.913 1.00 36.83 ? 116 LEU A CB 1 ATOM 637 C CG . LEU A 1 80 ? 54.855 75.870 15.416 1.00 44.54 ? 116 LEU A CG 1 ATOM 638 C CD1 . LEU A 1 80 ? 55.671 77.109 15.069 1.00 50.02 ? 116 LEU A CD1 1 ATOM 639 C CD2 . LEU A 1 80 ? 55.591 74.612 15.015 1.00 44.45 ? 116 LEU A CD2 1 ATOM 640 N N . GLU A 1 81 ? 53.660 73.606 19.457 1.00 38.02 ? 117 GLU A N 1 ATOM 641 C CA . GLU A 1 81 ? 53.506 73.478 20.894 1.00 35.08 ? 117 GLU A CA 1 ATOM 642 C C . GLU A 1 81 ? 54.823 73.800 21.587 1.00 40.34 ? 117 GLU A C 1 ATOM 643 O O . GLU A 1 81 ? 55.854 73.211 21.261 1.00 42.42 ? 117 GLU A O 1 ATOM 644 C CB . GLU A 1 81 ? 53.077 72.047 21.209 1.00 40.17 ? 117 GLU A CB 1 ATOM 645 C CG . GLU A 1 81 ? 52.823 71.714 22.679 1.00 34.05 ? 117 GLU A CG 1 ATOM 646 C CD . GLU A 1 81 ? 52.354 70.266 22.854 1.00 39.17 ? 117 GLU A CD 1 ATOM 647 O OE1 . GLU A 1 81 ? 51.172 69.977 22.541 1.00 38.05 ? 117 GLU A OE1 1 ATOM 648 O OE2 . GLU A 1 81 ? 53.170 69.414 23.291 1.00 41.79 ? 117 GLU A OE2 1 ATOM 649 N N . TYR A 1 82 ? 54.795 74.738 22.533 1.00 36.57 ? 118 TYR A N 1 ATOM 650 C CA . TYR A 1 82 ? 55.974 75.033 23.344 1.00 36.99 ? 118 TYR A CA 1 ATOM 651 C C . TYR A 1 82 ? 55.590 75.326 24.798 1.00 37.38 ? 118 TYR A C 1 ATOM 652 O O . TYR A 1 82 ? 54.405 75.347 25.141 1.00 36.88 ? 118 TYR A O 1 ATOM 653 C CB . TYR A 1 82 ? 56.772 76.198 22.743 1.00 38.76 ? 118 TYR A CB 1 ATOM 654 C CG . TYR A 1 82 ? 56.018 77.510 22.634 1.00 39.97 ? 118 TYR A CG 1 ATOM 655 C CD1 . TYR A 1 82 ? 55.034 77.690 21.678 1.00 38.45 ? 118 TYR A CD1 1 ATOM 656 C CD2 . TYR A 1 82 ? 56.317 78.577 23.468 1.00 41.90 ? 118 TYR A CD2 1 ATOM 657 C CE1 . TYR A 1 82 ? 54.357 78.889 21.564 1.00 37.77 ? 118 TYR A CE1 1 ATOM 658 C CE2 . TYR A 1 82 ? 55.646 79.779 23.364 1.00 41.25 ? 118 TYR A CE2 1 ATOM 659 C CZ . TYR A 1 82 ? 54.662 79.928 22.409 1.00 44.38 ? 118 TYR A CZ 1 ATOM 660 O OH . TYR A 1 82 ? 53.981 81.121 22.298 1.00 47.20 ? 118 TYR A OH 1 ATOM 661 N N . ASN A 1 83 ? 56.584 75.560 25.649 1.00 35.51 ? 119 ASN A N 1 ATOM 662 C CA . ASN A 1 83 ? 56.324 75.739 27.074 1.00 37.53 ? 119 ASN A CA 1 ATOM 663 C C . ASN A 1 83 ? 55.518 74.571 27.633 1.00 37.17 ? 119 ASN A C 1 ATOM 664 O O . ASN A 1 83 ? 54.599 74.775 28.418 1.00 34.00 ? 119 ASN A O 1 ATOM 665 C CB . ASN A 1 83 ? 55.547 77.035 27.342 1.00 41.37 ? 119 ASN A CB 1 ATOM 666 C CG . ASN A 1 83 ? 56.401 78.288 27.193 1.00 44.40 ? 119 ASN A CG 1 ATOM 667 O OD1 . ASN A 1 83 ? 57.633 78.242 27.284 1.00 44.77 ? 119 ASN A OD1 1 ATOM 668 N ND2 . ASN A 1 83 ? 55.740 79.420 26.986 1.00 40.69 ? 119 ASN A ND2 1 ATOM 669 N N . TYR A 1 84 ? 55.848 73.353 27.214 1.00 34.74 ? 120 TYR A N 1 ATOM 670 C CA . TYR A 1 84 ? 55.111 72.164 27.639 1.00 35.96 ? 120 TYR A CA 1 ATOM 671 C C . TYR A 1 84 ? 55.347 71.871 29.116 1.00 35.54 ? 120 TYR A C 1 ATOM 672 O O . TYR A 1 84 ? 56.491 71.889 29.565 1.00 38.93 ? 120 TYR A O 1 ATOM 673 C CB . TYR A 1 84 ? 55.547 70.977 26.784 1.00 36.19 ? 120 TYR A CB 1 ATOM 674 C CG . TYR A 1 84 ? 55.105 69.621 27.285 1.00 39.39 ? 120 TYR A CG 1 ATOM 675 C CD1 . TYR A 1 84 ? 55.884 68.900 28.177 1.00 43.45 ? 120 TYR A CD1 1 ATOM 676 C CD2 . TYR A 1 84 ? 53.927 69.047 26.839 1.00 41.53 ? 120 TYR A CD2 1 ATOM 677 C CE1 . TYR A 1 84 ? 55.491 67.641 28.631 1.00 43.47 ? 120 TYR A CE1 1 ATOM 678 C CE2 . TYR A 1 84 ? 53.526 67.796 27.285 1.00 45.89 ? 120 TYR A CE2 1 ATOM 679 C CZ . TYR A 1 84 ? 54.310 67.097 28.180 1.00 43.45 ? 120 TYR A CZ 1 ATOM 680 O OH . TYR A 1 84 ? 53.911 65.845 28.618 1.00 52.37 ? 120 TYR A OH 1 ATOM 681 N N . VAL A 1 85 ? 54.276 71.611 29.875 1.00 34.21 ? 121 VAL A N 1 ATOM 682 C CA . VAL A 1 85 ? 54.412 71.227 31.291 1.00 31.17 ? 121 VAL A CA 1 ATOM 683 C C . VAL A 1 85 ? 53.548 70.014 31.622 1.00 32.89 ? 121 VAL A C 1 ATOM 684 O O . VAL A 1 85 ? 52.326 70.095 31.611 1.00 33.33 ? 121 VAL A O 1 ATOM 685 C CB . VAL A 1 85 ? 54.020 72.368 32.255 1.00 32.42 ? 121 VAL A CB 1 ATOM 686 C CG1 . VAL A 1 85 ? 54.136 71.899 33.719 1.00 36.08 ? 121 VAL A CG1 1 ATOM 687 C CG2 . VAL A 1 85 ? 54.873 73.599 32.008 1.00 35.40 ? 121 VAL A CG2 1 ATOM 688 N N . LYS A 1 86 ? 54.183 68.887 31.908 1.00 33.16 ? 122 LYS A N 1 ATOM 689 C CA . LYS A 1 86 ? 53.451 67.652 32.137 1.00 34.91 ? 122 LYS A CA 1 ATOM 690 C C . LYS A 1 86 ? 52.572 67.759 33.380 1.00 33.16 ? 122 LYS A C 1 ATOM 691 O O . LYS A 1 86 ? 52.929 68.429 34.361 1.00 31.55 ? 122 LYS A O 1 ATOM 692 C CB . LYS A 1 86 ? 54.421 66.478 32.293 1.00 31.35 ? 122 LYS A CB 1 ATOM 693 C CG . LYS A 1 86 ? 53.750 65.138 32.605 1.00 34.57 ? 122 LYS A CG 1 ATOM 694 C CD . LYS A 1 86 ? 54.749 63.989 32.500 1.00 39.94 ? 122 LYS A CD 1 ATOM 695 C CE . LYS A 1 86 ? 54.166 62.696 33.014 1.00 36.79 ? 122 LYS A CE 1 ATOM 696 N NZ . LYS A 1 86 ? 53.576 62.901 34.366 1.00 34.90 ? 122 LYS A NZ 1 ATOM 697 N N . GLN A 1 87 ? 51.416 67.109 33.331 1.00 30.73 ? 123 GLN A N 1 ATOM 698 C CA . GLN A 1 87 ? 50.633 66.909 34.540 1.00 29.46 ? 123 GLN A CA 1 ATOM 699 C C . GLN A 1 87 ? 50.627 65.419 34.875 1.00 29.43 ? 123 GLN A C 1 ATOM 700 O O . GLN A 1 87 ? 51.618 64.898 35.400 1.00 30.74 ? 123 GLN A O 1 ATOM 701 C CB . GLN A 1 87 ? 49.217 67.481 34.410 1.00 28.19 ? 123 GLN A CB 1 ATOM 702 C CG . GLN A 1 87 ? 48.564 67.673 35.773 1.00 34.38 ? 123 GLN A CG 1 ATOM 703 C CD . GLN A 1 87 ? 47.116 68.086 35.692 1.00 41.29 ? 123 GLN A CD 1 ATOM 704 O OE1 . GLN A 1 87 ? 46.372 67.634 34.814 1.00 36.58 ? 123 GLN A OE1 1 ATOM 705 N NE2 . GLN A 1 87 ? 46.699 68.954 36.616 1.00 39.03 ? 123 GLN A NE2 1 ATOM 706 N N . TRP A 1 88 ? 49.540 64.714 34.569 1.00 24.87 ? 124 TRP A N 1 ATOM 707 C CA . TRP A 1 88 ? 49.484 63.288 34.928 1.00 25.98 ? 124 TRP A CA 1 ATOM 708 C C . TRP A 1 88 ? 49.978 62.438 33.745 1.00 29.41 ? 124 TRP A C 1 ATOM 709 O O . TRP A 1 88 ? 50.894 62.860 33.033 1.00 27.99 ? 124 TRP A O 1 ATOM 710 C CB . TRP A 1 88 ? 48.087 62.871 35.417 1.00 25.23 ? 124 TRP A CB 1 ATOM 711 C CG . TRP A 1 88 ? 47.477 63.855 36.375 1.00 29.11 ? 124 TRP A CG 1 ATOM 712 C CD1 . TRP A 1 88 ? 46.237 64.450 36.285 1.00 29.24 ? 124 TRP A CD1 1 ATOM 713 C CD2 . TRP A 1 88 ? 48.088 64.386 37.555 1.00 26.59 ? 124 TRP A CD2 1 ATOM 714 N NE1 . TRP A 1 88 ? 46.046 65.307 37.347 1.00 25.65 ? 124 TRP A NE1 1 ATOM 715 C CE2 . TRP A 1 88 ? 47.161 65.277 38.145 1.00 26.24 ? 124 TRP A CE2 1 ATOM 716 C CE3 . TRP A 1 88 ? 49.319 64.175 38.186 1.00 27.18 ? 124 TRP A CE3 1 ATOM 717 C CZ2 . TRP A 1 88 ? 47.442 65.978 39.322 1.00 24.71 ? 124 TRP A CZ2 1 ATOM 718 C CZ3 . TRP A 1 88 ? 49.596 64.870 39.362 1.00 29.85 ? 124 TRP A CZ3 1 ATOM 719 C CH2 . TRP A 1 88 ? 48.657 65.756 39.916 1.00 29.23 ? 124 TRP A CH2 1 ATOM 720 N N . ARG A 1 89 ? 49.400 61.257 33.525 1.00 25.27 ? 125 ARG A N 1 ATOM 721 C CA . ARG A 1 89 ? 49.924 60.372 32.474 1.00 27.54 ? 125 ARG A CA 1 ATOM 722 C C . ARG A 1 89 ? 49.802 60.998 31.077 1.00 28.06 ? 125 ARG A C 1 ATOM 723 O O . ARG A 1 89 ? 50.698 60.862 30.242 1.00 28.44 ? 125 ARG A O 1 ATOM 724 C CB . ARG A 1 89 ? 49.247 58.992 32.512 1.00 28.07 ? 125 ARG A CB 1 ATOM 725 C CG . ARG A 1 89 ? 49.900 57.927 31.593 1.00 29.90 ? 125 ARG A CG 1 ATOM 726 C CD . ARG A 1 89 ? 49.141 56.576 31.615 1.00 29.77 ? 125 ARG A CD 1 ATOM 727 N NE . ARG A 1 89 ? 49.053 55.982 32.954 1.00 27.34 ? 125 ARG A NE 1 ATOM 728 C CZ . ARG A 1 89 ? 49.988 55.205 33.499 1.00 29.22 ? 125 ARG A CZ 1 ATOM 729 N NH1 . ARG A 1 89 ? 51.097 54.908 32.826 1.00 26.85 ? 125 ARG A NH1 1 ATOM 730 N NH2 . ARG A 1 89 ? 49.818 54.715 34.722 1.00 27.17 ? 125 ARG A NH2 1 ATOM 731 N N . HIS A 1 90 ? 48.697 61.692 30.833 1.00 26.99 ? 126 HIS A N 1 ATOM 732 C CA . HIS A 1 90 ? 48.389 62.193 29.500 1.00 29.94 ? 126 HIS A CA 1 ATOM 733 C C . HIS A 1 90 ? 48.241 63.716 29.478 1.00 28.21 ? 126 HIS A C 1 ATOM 734 O O . HIS A 1 90 ? 48.543 64.371 28.482 1.00 29.60 ? 126 HIS A O 1 ATOM 735 C CB . HIS A 1 90 ? 47.099 61.532 28.973 1.00 28.92 ? 126 HIS A CB 1 ATOM 736 C CG . HIS A 1 90 ? 47.114 60.028 29.010 1.00 26.65 ? 126 HIS A CG 1 ATOM 737 N ND1 . HIS A 1 90 ? 47.846 59.266 28.126 1.00 28.94 ? 126 HIS A ND1 1 ATOM 738 C CD2 . HIS A 1 90 ? 46.459 59.149 29.809 1.00 27.72 ? 126 HIS A CD2 1 ATOM 739 C CE1 . HIS A 1 90 ? 47.664 57.984 28.394 1.00 28.50 ? 126 HIS A CE1 1 ATOM 740 N NE2 . HIS A 1 90 ? 46.824 57.886 29.410 1.00 28.31 ? 126 HIS A NE2 1 ATOM 741 N N . SER A 1 91 ? 47.761 64.280 30.577 1.00 29.83 ? 127 SER A N 1 ATOM 742 C CA . SER A 1 91 ? 47.476 65.710 30.628 1.00 29.08 ? 127 SER A CA 1 ATOM 743 C C . SER A 1 91 ? 48.723 66.566 30.761 1.00 29.19 ? 127 SER A C 1 ATOM 744 O O . SER A 1 91 ? 49.762 66.117 31.241 1.00 28.61 ? 127 SER A O 1 ATOM 745 C CB . SER A 1 91 ? 46.504 66.030 31.779 1.00 27.86 ? 127 SER A CB 1 ATOM 746 O OG . SER A 1 91 ? 46.986 65.563 33.018 1.00 24.75 ? 127 SER A OG 1 ATOM 747 N N . TYR A 1 92 ? 48.591 67.820 30.358 1.00 26.48 ? 128 TYR A N 1 ATOM 748 C CA . TYR A 1 92 ? 49.675 68.770 30.427 1.00 28.77 ? 128 TYR A CA 1 ATOM 749 C C . TYR A 1 92 ? 49.122 70.135 30.052 1.00 34.92 ? 128 TYR A C 1 ATOM 750 O O . TYR A 1 92 ? 47.967 70.233 29.652 1.00 38.39 ? 128 TYR A O 1 ATOM 751 C CB . TYR A 1 92 ? 50.823 68.351 29.501 1.00 32.40 ? 128 TYR A CB 1 ATOM 752 C CG . TYR A 1 92 ? 50.531 68.234 28.008 1.00 39.72 ? 128 TYR A CG 1 ATOM 753 C CD1 . TYR A 1 92 ? 50.522 69.353 27.178 1.00 38.73 ? 128 TYR A CD1 1 ATOM 754 C CD2 . TYR A 1 92 ? 50.347 66.985 27.416 1.00 43.67 ? 128 TYR A CD2 1 ATOM 755 C CE1 . TYR A 1 92 ? 50.294 69.230 25.792 1.00 40.95 ? 128 TYR A CE1 1 ATOM 756 C CE2 . TYR A 1 92 ? 50.113 66.850 26.053 1.00 42.44 ? 128 TYR A CE2 1 ATOM 757 C CZ . TYR A 1 92 ? 50.089 67.972 25.236 1.00 47.45 ? 128 TYR A CZ 1 ATOM 758 O OH . TYR A 1 92 ? 49.869 67.811 23.869 1.00 42.03 ? 128 TYR A OH 1 ATOM 759 N N . THR A 1 93 ? 49.916 71.191 30.197 1.00 29.06 ? 129 THR A N 1 ATOM 760 C CA . THR A 1 93 ? 49.531 72.472 29.605 1.00 30.92 ? 129 THR A CA 1 ATOM 761 C C . THR A 1 93 ? 50.644 72.972 28.705 1.00 30.92 ? 129 THR A C 1 ATOM 762 O O . THR A 1 93 ? 51.795 72.589 28.862 1.00 31.06 ? 129 THR A O 1 ATOM 763 C CB . THR A 1 93 ? 49.217 73.553 30.656 1.00 31.09 ? 129 THR A CB 1 ATOM 764 O OG1 . THR A 1 93 ? 50.425 73.940 31.316 1.00 33.11 ? 129 THR A OG1 1 ATOM 765 C CG2 . THR A 1 93 ? 48.216 73.031 31.691 1.00 31.50 ? 129 THR A CG2 1 ATOM 766 N N . ALA A 1 94 ? 50.299 73.821 27.751 1.00 28.58 ? 130 ALA A N 1 ATOM 767 C CA . ALA A 1 94 ? 51.311 74.328 26.845 1.00 33.07 ? 130 ALA A CA 1 ATOM 768 C C . ALA A 1 94 ? 50.869 75.653 26.250 1.00 35.05 ? 130 ALA A C 1 ATOM 769 O O . ALA A 1 94 ? 49.700 76.028 26.353 1.00 31.16 ? 130 ALA A O 1 ATOM 770 C CB . ALA A 1 94 ? 51.591 73.305 25.740 1.00 26.71 ? 130 ALA A CB 1 ATOM 771 N N . SER A 1 95 ? 51.818 76.354 25.635 1.00 36.45 ? 131 SER A N 1 ATOM 772 C CA . SER A 1 95 ? 51.520 77.515 24.805 1.00 34.89 ? 131 SER A CA 1 ATOM 773 C C . SER A 1 95 ? 51.493 77.059 23.353 1.00 37.39 ? 131 SER A C 1 ATOM 774 O O . SER A 1 95 ? 52.100 76.041 23.014 1.00 34.59 ? 131 SER A O 1 ATOM 775 C CB . SER A 1 95 ? 52.594 78.589 24.993 1.00 37.72 ? 131 SER A CB 1 ATOM 776 O OG . SER A 1 95 ? 52.560 79.114 26.312 1.00 42.32 ? 131 SER A OG 1 ATOM 777 N N . TYR A 1 96 ? 50.798 77.807 22.497 1.00 34.37 ? 132 TYR A N 1 ATOM 778 C CA . TYR A 1 96 ? 50.647 77.423 21.094 1.00 37.12 ? 132 TYR A CA 1 ATOM 779 C C . TYR A 1 96 ? 50.748 78.608 20.144 1.00 40.17 ? 132 TYR A C 1 ATOM 780 O O . TYR A 1 96 ? 50.292 79.714 20.449 1.00 39.64 ? 132 TYR A O 1 ATOM 781 C CB . TYR A 1 96 ? 49.313 76.717 20.871 1.00 32.27 ? 132 TYR A CB 1 ATOM 782 C CG . TYR A 1 96 ? 49.239 75.363 21.522 1.00 36.81 ? 132 TYR A CG 1 ATOM 783 C CD1 . TYR A 1 96 ? 49.638 74.224 20.838 1.00 35.92 ? 132 TYR A CD1 1 ATOM 784 C CD2 . TYR A 1 96 ? 48.774 75.218 22.825 1.00 33.32 ? 132 TYR A CD2 1 ATOM 785 C CE1 . TYR A 1 96 ? 49.579 72.981 21.431 1.00 37.35 ? 132 TYR A CE1 1 ATOM 786 C CE2 . TYR A 1 96 ? 48.710 73.976 23.426 1.00 32.05 ? 132 TYR A CE2 1 ATOM 787 C CZ . TYR A 1 96 ? 49.117 72.860 22.722 1.00 33.05 ? 132 TYR A CZ 1 ATOM 788 O OH . TYR A 1 96 ? 49.062 71.615 23.306 1.00 31.71 ? 132 TYR A OH 1 ATOM 789 N N . ASP A 1 97 ? 51.360 78.365 18.993 1.00 38.75 ? 133 ASP A N 1 ATOM 790 C CA . ASP A 1 97 ? 51.404 79.336 17.912 1.00 41.25 ? 133 ASP A CA 1 ATOM 791 C C . ASP A 1 97 ? 50.980 78.643 16.640 1.00 41.55 ? 133 ASP A C 1 ATOM 792 O O . ASP A 1 97 ? 51.308 77.479 16.436 1.00 39.46 ? 133 ASP A O 1 ATOM 793 C CB . ASP A 1 97 ? 52.811 79.895 17.735 1.00 40.56 ? 133 ASP A CB 1 ATOM 794 C CG . ASP A 1 97 ? 53.014 81.188 18.481 1.00 48.69 ? 133 ASP A CG 1 ATOM 795 O OD1 . ASP A 1 97 ? 52.000 81.793 18.892 1.00 50.70 ? 133 ASP A OD1 1 ATOM 796 O OD2 . ASP A 1 97 ? 54.180 81.603 18.651 1.00 53.80 ? 133 ASP A OD2 1 ATOM 797 N N . ILE A 1 98 ? 50.250 79.358 15.791 1.00 39.45 ? 134 ILE A N 1 ATOM 798 C CA . ILE A 1 98 ? 49.826 78.823 14.511 1.00 41.45 ? 134 ILE A CA 1 ATOM 799 C C . ILE A 1 98 ? 50.607 79.527 13.411 1.00 45.84 ? 134 ILE A C 1 ATOM 800 O O . ILE A 1 98 ? 50.681 80.755 13.382 1.00 48.17 ? 134 ILE A O 1 ATOM 801 C CB . ILE A 1 98 ? 48.322 79.023 14.292 1.00 40.51 ? 134 ILE A CB 1 ATOM 802 C CG1 . ILE A 1 98 ? 47.554 78.589 15.541 1.00 40.92 ? 134 ILE A CG1 1 ATOM 803 C CG2 . ILE A 1 98 ? 47.860 78.255 13.066 1.00 40.86 ? 134 ILE A CG2 1 ATOM 804 C CD1 . ILE A 1 98 ? 46.085 78.947 15.517 1.00 43.35 ? 134 ILE A CD1 1 ATOM 805 N N . TYR A 1 99 ? 51.207 78.746 12.524 1.00 46.49 ? 135 TYR A N 1 ATOM 806 C CA . TYR A 1 99 ? 52.032 79.280 11.448 1.00 45.61 ? 135 TYR A CA 1 ATOM 807 C C . TYR A 1 99 ? 51.294 79.009 10.154 1.00 47.40 ? 135 TYR A C 1 ATOM 808 O O . TYR A 1 99 ? 50.913 77.872 9.890 1.00 46.74 ? 135 TYR A O 1 ATOM 809 C CB . TYR A 1 99 ? 53.394 78.586 11.470 1.00 49.19 ? 135 TYR A CB 1 ATOM 810 C CG . TYR A 1 99 ? 54.369 78.943 10.363 1.00 54.53 ? 135 TYR A CG 1 ATOM 811 C CD1 . TYR A 1 99 ? 55.245 80.009 10.495 1.00 55.84 ? 135 TYR A CD1 1 ATOM 812 C CD2 . TYR A 1 99 ? 54.451 78.173 9.209 1.00 55.62 ? 135 TYR A CD2 1 ATOM 813 C CE1 . TYR A 1 99 ? 56.156 80.321 9.492 1.00 59.58 ? 135 TYR A CE1 1 ATOM 814 C CE2 . TYR A 1 99 ? 55.359 78.474 8.201 1.00 59.67 ? 135 TYR A CE2 1 ATOM 815 C CZ . TYR A 1 99 ? 56.207 79.548 8.348 1.00 60.56 ? 135 TYR A CZ 1 ATOM 816 O OH . TYR A 1 99 ? 57.103 79.849 7.348 1.00 59.33 ? 135 TYR A OH 1 ATOM 817 N N . ASP A 1 100 ? 51.056 80.062 9.372 1.00 53.04 ? 136 ASP A N 1 ATOM 818 C CA . ASP A 1 100 ? 50.369 79.948 8.086 1.00 50.91 ? 136 ASP A CA 1 ATOM 819 C C . ASP A 1 100 ? 51.375 79.493 7.035 1.00 54.02 ? 136 ASP A C 1 ATOM 820 O O . ASP A 1 100 ? 52.409 80.137 6.837 1.00 53.07 ? 136 ASP A O 1 ATOM 821 C CB . ASP A 1 100 ? 49.740 81.293 7.689 1.00 56.09 ? 136 ASP A CB 1 ATOM 822 C CG . ASP A 1 100 ? 48.858 81.196 6.445 1.00 56.18 ? 136 ASP A CG 1 ATOM 823 O OD1 . ASP A 1 100 ? 49.213 80.450 5.506 1.00 51.38 ? 136 ASP A OD1 1 ATOM 824 O OD2 . ASP A 1 100 ? 47.806 81.878 6.408 1.00 57.01 ? 136 ASP A OD2 1 ATOM 825 N N . LEU A 1 101 ? 51.072 78.376 6.376 1.00 50.82 ? 137 LEU A N 1 ATOM 826 C CA . LEU A 1 101 ? 52.023 77.730 5.473 1.00 54.81 ? 137 LEU A CA 1 ATOM 827 C C . LEU A 1 101 ? 51.976 78.298 4.057 1.00 54.59 ? 137 LEU A C 1 ATOM 828 O O . LEU A 1 101 ? 52.926 78.146 3.288 1.00 57.15 ? 137 LEU A O 1 ATOM 829 C CB . LEU A 1 101 ? 51.792 76.216 5.443 1.00 47.68 ? 137 LEU A CB 1 ATOM 830 C CG . LEU A 1 101 ? 52.152 75.469 6.729 1.00 48.96 ? 137 LEU A CG 1 ATOM 831 C CD1 . LEU A 1 101 ? 51.618 74.053 6.700 1.00 47.16 ? 137 LEU A CD1 1 ATOM 832 C CD2 . LEU A 1 101 ? 53.659 75.476 6.953 1.00 55.48 ? 137 LEU A CD2 1 ATOM 833 N N . ASN A 1 102 ? 50.866 78.938 3.717 1.00 52.78 ? 138 ASN A N 1 ATOM 834 C CA . ASN A 1 102 ? 50.737 79.577 2.420 1.00 57.57 ? 138 ASN A CA 1 ATOM 835 C C . ASN A 1 102 ? 51.404 80.939 2.422 1.00 60.69 ? 138 ASN A C 1 ATOM 836 O O . ASN A 1 102 ? 52.149 81.268 1.498 1.00 62.47 ? 138 ASN A O 1 ATOM 837 C CB . ASN A 1 102 ? 49.271 79.686 2.013 1.00 58.20 ? 138 ASN A CB 1 ATOM 838 C CG . ASN A 1 102 ? 48.699 78.356 1.556 1.00 65.83 ? 138 ASN A CG 1 ATOM 839 O OD1 . ASN A 1 102 ? 49.327 77.630 0.777 1.00 66.29 ? 138 ASN A OD1 1 ATOM 840 N ND2 . ASN A 1 102 ? 47.509 78.020 2.050 1.00 65.15 ? 138 ASN A ND2 1 ATOM 841 N N . LYS A 1 103 ? 51.145 81.724 3.465 1.00 55.28 ? 139 LYS A N 1 ATOM 842 C CA . LYS A 1 103 ? 51.794 83.020 3.621 1.00 55.85 ? 139 LYS A CA 1 ATOM 843 C C . LYS A 1 103 ? 53.210 82.868 4.190 1.00 57.45 ? 139 LYS A C 1 ATOM 844 O O . LYS A 1 103 ? 54.027 83.782 4.103 1.00 59.71 ? 139 LYS A O 1 ATOM 845 C CB . LYS A 1 103 ? 50.946 83.949 4.499 1.00 56.98 ? 139 LYS A CB 1 ATOM 846 C CG . LYS A 1 103 ? 49.542 84.212 3.955 1.00 60.52 ? 139 LYS A CG 1 ATOM 847 C CD . LYS A 1 103 ? 48.749 85.175 4.845 1.00 54.46 ? 139 LYS A CD 1 ATOM 848 N N . ARG A 1 104 ? 53.499 81.705 4.763 1.00 57.55 ? 140 ARG A N 1 ATOM 849 C CA . ARG A 1 104 ? 54.781 81.470 5.424 1.00 57.89 ? 140 ARG A CA 1 ATOM 850 C C . ARG A 1 104 ? 55.033 82.455 6.573 1.00 57.12 ? 140 ARG A C 1 ATOM 851 O O . ARG A 1 104 ? 56.180 82.828 6.838 1.00 57.47 ? 140 ARG A O 1 ATOM 852 C CB . ARG A 1 104 ? 55.930 81.513 4.407 1.00 60.88 ? 140 ARG A CB 1 ATOM 853 C CG . ARG A 1 104 ? 55.968 80.322 3.455 1.00 63.17 ? 140 ARG A CG 1 ATOM 854 C CD . ARG A 1 104 ? 57.053 80.487 2.391 1.00 65.80 ? 140 ARG A CD 1 ATOM 855 N N . GLN A 1 105 ? 53.958 82.861 7.253 1.00 60.45 ? 141 GLN A N 1 ATOM 856 C CA . GLN A 1 105 ? 54.032 83.826 8.358 1.00 57.95 ? 141 GLN A CA 1 ATOM 857 C C . GLN A 1 105 ? 53.446 83.262 9.643 1.00 53.94 ? 141 GLN A C 1 ATOM 858 O O . GLN A 1 105 ? 52.460 82.531 9.605 1.00 52.03 ? 141 GLN A O 1 ATOM 859 C CB . GLN A 1 105 ? 53.224 85.083 8.038 1.00 58.98 ? 141 GLN A CB 1 ATOM 860 C CG . GLN A 1 105 ? 53.655 85.885 6.832 1.00 66.21 ? 141 GLN A CG 1 ATOM 861 C CD . GLN A 1 105 ? 52.608 86.926 6.456 1.00 73.46 ? 141 GLN A CD 1 ATOM 862 O OE1 . GLN A 1 105 ? 51.595 87.083 7.149 1.00 71.61 ? 141 GLN A OE1 1 ATOM 863 N NE2 . GLN A 1 105 ? 52.840 87.634 5.351 1.00 77.34 ? 141 GLN A NE2 1 ATOM 864 N N . LEU A 1 106 ? 54.029 83.637 10.780 1.00 53.67 ? 142 LEU A N 1 ATOM 865 C CA . LEU A 1 106 ? 53.398 83.387 12.073 1.00 52.89 ? 142 LEU A CA 1 ATOM 866 C C . LEU A 1 106 ? 52.115 84.204 12.177 1.00 50.47 ? 142 LEU A C 1 ATOM 867 O O . LEU A 1 106 ? 52.060 85.350 11.740 1.00 50.71 ? 142 LEU A O 1 ATOM 868 C CB . LEU A 1 106 ? 54.335 83.757 13.228 1.00 54.43 ? 142 LEU A CB 1 ATOM 869 C CG . LEU A 1 106 ? 55.099 82.647 13.957 1.00 57.02 ? 142 LEU A CG 1 ATOM 870 C CD1 . LEU A 1 106 ? 56.069 81.930 13.038 1.00 58.36 ? 142 LEU A CD1 1 ATOM 871 C CD2 . LEU A 1 106 ? 55.848 83.231 15.143 1.00 63.82 ? 142 LEU A CD2 1 ATOM 872 N N . ILE A 1 107 ? 51.077 83.603 12.742 1.00 47.20 ? 143 ILE A N 1 ATOM 873 C CA . ILE A 1 107 ? 49.834 84.309 12.995 1.00 47.93 ? 143 ILE A CA 1 ATOM 874 C C . ILE A 1 107 ? 49.921 84.998 14.359 1.00 52.78 ? 143 ILE A C 1 ATOM 875 O O . ILE A 1 107 ? 50.197 84.353 15.368 1.00 52.77 ? 143 ILE A O 1 ATOM 876 C CB . ILE A 1 107 ? 48.644 83.341 12.959 1.00 47.71 ? 143 ILE A CB 1 ATOM 877 C CG1 . ILE A 1 107 ? 48.420 82.851 11.524 1.00 48.06 ? 143 ILE A CG1 1 ATOM 878 C CG2 . ILE A 1 107 ? 47.395 83.997 13.512 1.00 48.55 ? 143 ILE A CG2 1 ATOM 879 C CD1 . ILE A 1 107 ? 47.087 82.194 11.305 1.00 46.68 ? 143 ILE A CD1 1 ATOM 880 N N . THR A 1 108 ? 49.701 86.309 14.388 1.00 51.58 ? 144 THR A N 1 ATOM 881 C CA . THR A 1 108 ? 49.892 87.078 15.617 1.00 51.90 ? 144 THR A CA 1 ATOM 882 C C . THR A 1 108 ? 48.581 87.596 16.195 1.00 51.11 ? 144 THR A C 1 ATOM 883 O O . THR A 1 108 ? 48.558 88.190 17.273 1.00 51.57 ? 144 THR A O 1 ATOM 884 C CB . THR A 1 108 ? 50.824 88.279 15.384 1.00 57.12 ? 144 THR A CB 1 ATOM 885 O OG1 . THR A 1 108 ? 50.279 89.105 14.345 1.00 61.08 ? 144 THR A OG1 1 ATOM 886 C CG2 . THR A 1 108 ? 52.225 87.813 14.982 1.00 55.04 ? 144 THR A CG2 1 ATOM 887 N N . GLU A 1 109 ? 47.492 87.358 15.477 1.00 54.38 ? 145 GLU A N 1 ATOM 888 C CA . GLU A 1 109 ? 46.167 87.822 15.880 1.00 58.56 ? 145 GLU A CA 1 ATOM 889 C C . GLU A 1 109 ? 45.328 86.702 16.518 1.00 58.25 ? 145 GLU A C 1 ATOM 890 O O . GLU A 1 109 ? 45.389 85.546 16.087 1.00 54.65 ? 145 GLU A O 1 ATOM 891 C CB . GLU A 1 109 ? 45.444 88.410 14.660 1.00 61.53 ? 145 GLU A CB 1 ATOM 892 C CG . GLU A 1 109 ? 43.922 88.501 14.775 1.00 65.30 ? 145 GLU A CG 1 ATOM 893 C CD . GLU A 1 109 ? 43.237 88.761 13.425 1.00 71.58 ? 145 GLU A CD 1 ATOM 894 O OE1 . GLU A 1 109 ? 43.933 89.186 12.470 1.00 73.78 ? 145 GLU A OE1 1 ATOM 895 O OE2 . GLU A 1 109 ? 42.004 88.532 13.320 1.00 67.62 ? 145 GLU A OE2 1 ATOM 896 N N . GLU A 1 110 ? 44.555 87.052 17.547 1.00 53.70 ? 146 GLU A N 1 ATOM 897 C CA . GLU A 1 110 ? 43.638 86.108 18.198 1.00 53.75 ? 146 GLU A CA 1 ATOM 898 C C . GLU A 1 110 ? 44.318 84.807 18.628 1.00 46.35 ? 146 GLU A C 1 ATOM 899 O O . GLU A 1 110 ? 43.777 83.719 18.427 1.00 44.83 ? 146 GLU A O 1 ATOM 900 C CB . GLU A 1 110 ? 42.446 85.793 17.283 1.00 51.11 ? 146 GLU A CB 1 ATOM 901 C CG . GLU A 1 110 ? 41.641 87.016 16.859 1.00 53.41 ? 146 GLU A CG 1 ATOM 902 C CD . GLU A 1 110 ? 41.118 87.832 18.035 1.00 58.17 ? 146 GLU A CD 1 ATOM 903 O OE1 . GLU A 1 110 ? 40.717 87.232 19.058 1.00 54.45 ? 146 GLU A OE1 1 ATOM 904 O OE2 . GLU A 1 110 ? 41.112 89.080 17.936 1.00 54.64 ? 146 GLU A OE2 1 ATOM 905 N N . ARG A 1 111 ? 45.496 84.929 19.231 1.00 46.46 ? 147 ARG A N 1 ATOM 906 C CA . ARG A 1 111 ? 46.316 83.769 19.562 1.00 44.71 ? 147 ARG A CA 1 ATOM 907 C C . ARG A 1 111 ? 45.652 82.817 20.551 1.00 41.12 ? 147 ARG A C 1 ATOM 908 O O . ARG A 1 111 ? 44.777 83.209 21.321 1.00 42.95 ? 147 ARG A O 1 ATOM 909 C CB . ARG A 1 111 ? 47.678 84.220 20.080 1.00 46.57 ? 147 ARG A CB 1 ATOM 910 C CG . ARG A 1 111 ? 48.611 84.678 18.975 1.00 52.03 ? 147 ARG A CG 1 ATOM 911 C CD . ARG A 1 111 ? 49.540 85.774 19.455 1.00 57.07 ? 147 ARG A CD 1 ATOM 912 N NE . ARG A 1 111 ? 50.463 85.298 20.476 1.00 62.21 ? 147 ARG A NE 1 ATOM 913 C CZ . ARG A 1 111 ? 51.728 84.966 20.237 1.00 67.67 ? 147 ARG A CZ 1 ATOM 914 N NH1 . ARG A 1 111 ? 52.221 85.072 19.004 1.00 63.69 ? 147 ARG A NH1 1 ATOM 915 N NH2 . ARG A 1 111 ? 52.503 84.536 21.229 1.00 64.93 ? 147 ARG A NH2 1 ATOM 916 N N . ILE A 1 112 ? 46.060 81.556 20.503 1.00 36.70 ? 148 ILE A N 1 ATOM 917 C CA . ILE A 1 112 ? 45.664 80.583 21.507 1.00 37.77 ? 148 ILE A CA 1 ATOM 918 C C . ILE A 1 112 ? 46.363 80.987 22.801 1.00 39.11 ? 148 ILE A C 1 ATOM 919 O O . ILE A 1 112 ? 47.555 81.303 22.779 1.00 42.50 ? 148 ILE A O 1 ATOM 920 C CB . ILE A 1 112 ? 46.067 79.158 21.068 1.00 39.88 ? 148 ILE A CB 1 ATOM 921 C CG1 . ILE A 1 112 ? 45.358 78.789 19.765 1.00 39.50 ? 148 ILE A CG1 1 ATOM 922 C CG2 . ILE A 1 112 ? 45.713 78.126 22.132 1.00 36.35 ? 148 ILE A CG2 1 ATOM 923 C CD1 . ILE A 1 112 ? 45.944 77.570 19.084 1.00 39.47 ? 148 ILE A CD1 1 ATOM 924 N N . PRO A 1 113 ? 45.625 81.006 23.932 1.00 39.91 ? 149 PRO A N 1 ATOM 925 C CA . PRO A 1 113 ? 46.177 81.519 25.199 1.00 37.31 ? 149 PRO A CA 1 ATOM 926 C C . PRO A 1 113 ? 47.299 80.645 25.742 1.00 38.67 ? 149 PRO A C 1 ATOM 927 O O . PRO A 1 113 ? 47.388 79.476 25.373 1.00 37.57 ? 149 PRO A O 1 ATOM 928 C CB . PRO A 1 113 ? 44.992 81.440 26.174 1.00 34.05 ? 149 PRO A CB 1 ATOM 929 C CG . PRO A 1 113 ? 43.807 81.058 25.371 1.00 40.33 ? 149 PRO A CG 1 ATOM 930 C CD . PRO A 1 113 ? 44.285 80.426 24.107 1.00 39.15 ? 149 PRO A CD 1 ATOM 931 N N . ASN A 1 114 ? 48.137 81.202 26.613 1.00 35.23 ? 150 ASN A N 1 ATOM 932 C CA . ASN A 1 114 ? 49.086 80.405 27.373 1.00 37.40 ? 150 ASN A CA 1 ATOM 933 C C . ASN A 1 114 ? 48.321 79.481 28.313 1.00 33.85 ? 150 ASN A C 1 ATOM 934 O O . ASN A 1 114 ? 47.144 79.699 28.587 1.00 34.72 ? 150 ASN A O 1 ATOM 935 C CB . ASN A 1 114 ? 50.031 81.297 28.183 1.00 41.81 ? 150 ASN A CB 1 ATOM 936 C CG . ASN A 1 114 ? 51.030 82.031 27.317 1.00 47.68 ? 150 ASN A CG 1 ATOM 937 O OD1 . ASN A 1 114 ? 51.674 81.436 26.451 1.00 46.84 ? 150 ASN A OD1 1 ATOM 938 N ND2 . ASN A 1 114 ? 51.156 83.339 27.541 1.00 50.45 ? 150 ASN A ND2 1 ATOM 939 N N . ASN A 1 115 ? 48.997 78.451 28.804 1.00 35.30 ? 151 ASN A N 1 ATOM 940 C CA . ASN A 1 115 ? 48.391 77.496 29.727 1.00 32.10 ? 151 ASN A CA 1 ATOM 941 C C . ASN A 1 115 ? 47.156 76.799 29.158 1.00 34.17 ? 151 ASN A C 1 ATOM 942 O O . ASN A 1 115 ? 46.250 76.418 29.905 1.00 35.25 ? 151 ASN A O 1 ATOM 943 C CB . ASN A 1 115 ? 48.051 78.164 31.063 1.00 32.61 ? 151 ASN A CB 1 ATOM 944 C CG . ASN A 1 115 ? 49.233 78.906 31.661 1.00 40.36 ? 151 ASN A CG 1 ATOM 945 O OD1 . ASN A 1 115 ? 50.237 78.301 32.044 1.00 41.78 ? 151 ASN A OD1 1 ATOM 946 N ND2 . ASN A 1 115 ? 49.115 80.226 31.751 1.00 38.96 ? 151 ASN A ND2 1 ATOM 947 N N . THR A 1 116 ? 47.130 76.616 27.842 1.00 33.33 ? 152 THR A N 1 ATOM 948 C CA . THR A 1 116 ? 46.059 75.855 27.200 1.00 29.81 ? 152 THR A CA 1 ATOM 949 C C . THR A 1 116 ? 46.179 74.375 27.555 1.00 30.38 ? 152 THR A C 1 ATOM 950 O O . THR A 1 116 ? 47.277 73.830 27.556 1.00 30.38 ? 152 THR A O 1 ATOM 951 C CB . THR A 1 116 ? 46.109 76.015 25.689 1.00 32.97 ? 152 THR A CB 1 ATOM 952 O OG1 . THR A 1 116 ? 45.640 77.328 25.345 1.00 34.32 ? 152 THR A OG1 1 ATOM 953 C CG2 . THR A 1 116 ? 45.231 74.966 25.012 1.00 29.72 ? 152 THR A CG2 1 ATOM 954 N N . GLN A 1 117 ? 45.048 73.732 27.842 1.00 29.76 ? 153 GLN A N 1 ATOM 955 C CA . GLN A 1 117 ? 45.040 72.373 28.380 1.00 29.44 ? 153 GLN A CA 1 ATOM 956 C C . GLN A 1 117 ? 44.884 71.297 27.300 1.00 29.93 ? 153 GLN A C 1 ATOM 957 O O . GLN A 1 117 ? 45.333 70.168 27.472 1.00 29.94 ? 153 GLN A O 1 ATOM 958 C CB . GLN A 1 117 ? 43.933 72.227 29.428 1.00 29.82 ? 153 GLN A CB 1 ATOM 959 C CG . GLN A 1 117 ? 44.159 73.053 30.718 1.00 29.75 ? 153 GLN A CG 1 ATOM 960 C CD . GLN A 1 117 ? 42.859 73.365 31.419 1.00 30.47 ? 153 GLN A CD 1 ATOM 961 O OE1 . GLN A 1 117 ? 42.012 74.077 30.880 1.00 31.46 ? 153 GLN A OE1 1 ATOM 962 N NE2 . GLN A 1 117 ? 42.686 72.828 32.624 1.00 33.24 ? 153 GLN A NE2 1 ATOM 963 N N . TRP A 1 118 ? 44.241 71.645 26.195 1.00 31.17 ? 154 TRP A N 1 ATOM 964 C CA . TRP A 1 118 ? 44.094 70.704 25.093 1.00 30.61 ? 154 TRP A CA 1 ATOM 965 C C . TRP A 1 118 ? 43.741 71.459 23.833 1.00 30.63 ? 154 TRP A C 1 ATOM 966 O O . TRP A 1 118 ? 43.023 72.447 23.897 1.00 31.03 ? 154 TRP A O 1 ATOM 967 C CB . TRP A 1 118 ? 43.001 69.682 25.394 1.00 31.99 ? 154 TRP A CB 1 ATOM 968 C CG . TRP A 1 118 ? 42.772 68.726 24.252 1.00 32.69 ? 154 TRP A CG 1 ATOM 969 C CD1 . TRP A 1 118 ? 41.681 68.668 23.428 1.00 36.62 ? 154 TRP A CD1 1 ATOM 970 C CD2 . TRP A 1 118 ? 43.671 67.703 23.795 1.00 32.20 ? 154 TRP A CD2 1 ATOM 971 N NE1 . TRP A 1 118 ? 41.843 67.667 22.491 1.00 33.66 ? 154 TRP A NE1 1 ATOM 972 C CE2 . TRP A 1 118 ? 43.055 67.062 22.697 1.00 34.52 ? 154 TRP A CE2 1 ATOM 973 C CE3 . TRP A 1 118 ? 44.930 67.264 24.217 1.00 34.76 ? 154 TRP A CE3 1 ATOM 974 C CZ2 . TRP A 1 118 ? 43.659 66.004 22.014 1.00 35.66 ? 154 TRP A CZ2 1 ATOM 975 C CZ3 . TRP A 1 118 ? 45.529 66.211 23.540 1.00 38.09 ? 154 TRP A CZ3 1 ATOM 976 C CH2 . TRP A 1 118 ? 44.895 65.597 22.450 1.00 34.72 ? 154 TRP A CH2 1 ATOM 977 N N . VAL A 1 119 ? 44.259 71.008 22.689 1.00 28.98 ? 155 VAL A N 1 ATOM 978 C CA . VAL A 1 119 ? 43.955 71.630 21.393 1.00 29.13 ? 155 VAL A CA 1 ATOM 979 C C . VAL A 1 119 ? 43.858 70.532 20.350 1.00 32.24 ? 155 VAL A C 1 ATOM 980 O O . VAL A 1 119 ? 44.564 69.525 20.459 1.00 31.42 ? 155 VAL A O 1 ATOM 981 C CB . VAL A 1 119 ? 45.075 72.580 20.916 1.00 31.16 ? 155 VAL A CB 1 ATOM 982 C CG1 . VAL A 1 119 ? 44.614 73.370 19.704 1.00 33.92 ? 155 VAL A CG1 1 ATOM 983 C CG2 . VAL A 1 119 ? 45.481 73.523 22.010 1.00 39.77 ? 155 VAL A CG2 1 ATOM 984 N N . THR A 1 120 ? 42.995 70.717 19.352 1.00 30.79 ? 156 THR A N 1 ATOM 985 C CA . THR A 1 120 ? 42.854 69.736 18.274 1.00 34.34 ? 156 THR A CA 1 ATOM 986 C C . THR A 1 120 ? 42.201 70.342 17.033 1.00 37.67 ? 156 THR A C 1 ATOM 987 O O . THR A 1 120 ? 41.193 71.046 17.144 1.00 35.30 ? 156 THR A O 1 ATOM 988 C CB . THR A 1 120 ? 42.015 68.512 18.711 1.00 36.95 ? 156 THR A CB 1 ATOM 989 O OG1 . THR A 1 120 ? 41.917 67.587 17.623 1.00 42.23 ? 156 THR A OG1 1 ATOM 990 C CG2 . THR A 1 120 ? 40.612 68.931 19.111 1.00 37.48 ? 156 THR A CG2 1 ATOM 991 N N . TRP A 1 121 ? 42.777 70.069 15.857 1.00 32.76 ? 157 TRP A N 1 ATOM 992 C CA . TRP A 1 121 ? 42.150 70.455 14.594 1.00 34.43 ? 157 TRP A CA 1 ATOM 993 C C . TRP A 1 121 ? 40.873 69.658 14.394 1.00 33.72 ? 157 TRP A C 1 ATOM 994 O O . TRP A 1 121 ? 40.724 68.571 14.944 1.00 38.85 ? 157 TRP A O 1 ATOM 995 C CB . TRP A 1 121 ? 43.074 70.163 13.403 1.00 34.74 ? 157 TRP A CB 1 ATOM 996 C CG . TRP A 1 121 ? 44.357 70.929 13.378 1.00 32.16 ? 157 TRP A CG 1 ATOM 997 C CD1 . TRP A 1 121 ? 45.604 70.441 13.638 1.00 33.48 ? 157 TRP A CD1 1 ATOM 998 C CD2 . TRP A 1 121 ? 44.527 72.312 13.056 1.00 31.22 ? 157 TRP A CD2 1 ATOM 999 N NE1 . TRP A 1 121 ? 46.542 71.436 13.493 1.00 32.03 ? 157 TRP A NE1 1 ATOM 1000 C CE2 . TRP A 1 121 ? 45.906 72.594 13.137 1.00 32.88 ? 157 TRP A CE2 1 ATOM 1001 C CE3 . TRP A 1 121 ? 43.647 73.342 12.709 1.00 34.08 ? 157 TRP A CE3 1 ATOM 1002 C CZ2 . TRP A 1 121 ? 46.424 73.865 12.898 1.00 34.67 ? 157 TRP A CZ2 1 ATOM 1003 C CZ3 . TRP A 1 121 ? 44.164 74.594 12.457 1.00 33.25 ? 157 TRP A CZ3 1 ATOM 1004 C CH2 . TRP A 1 121 ? 45.538 74.849 12.562 1.00 32.63 ? 157 TRP A CH2 1 ATOM 1005 N N . SER A 1 122 ? 39.956 70.198 13.600 1.00 34.22 ? 158 SER A N 1 ATOM 1006 C CA . SER A 1 122 ? 38.842 69.422 13.085 1.00 33.65 ? 158 SER A CA 1 ATOM 1007 C C . SER A 1 122 ? 39.465 68.333 12.226 1.00 33.59 ? 158 SER A C 1 ATOM 1008 O O . SER A 1 122 ? 40.623 68.458 11.838 1.00 36.26 ? 158 SER A O 1 ATOM 1009 C CB . SER A 1 122 ? 37.920 70.313 12.249 1.00 32.99 ? 158 SER A CB 1 ATOM 1010 O OG . SER A 1 122 ? 38.677 71.154 11.387 1.00 33.31 ? 158 SER A OG 1 ATOM 1011 N N . PRO A 1 123 ? 38.714 67.260 11.925 1.00 34.80 ? 159 PRO A N 1 ATOM 1012 C CA . PRO A 1 123 ? 39.282 66.140 11.154 1.00 36.79 ? 159 PRO A CA 1 ATOM 1013 C C . PRO A 1 123 ? 39.498 66.500 9.678 1.00 41.97 ? 159 PRO A C 1 ATOM 1014 O O . PRO A 1 123 ? 40.322 65.878 8.989 1.00 44.18 ? 159 PRO A O 1 ATOM 1015 C CB . PRO A 1 123 ? 38.215 65.042 11.269 1.00 36.79 ? 159 PRO A CB 1 ATOM 1016 C CG . PRO A 1 123 ? 37.181 65.554 12.222 1.00 39.42 ? 159 PRO A CG 1 ATOM 1017 C CD . PRO A 1 123 ? 37.295 67.049 12.233 1.00 34.99 ? 159 PRO A CD 1 ATOM 1018 N N . VAL A 1 124 ? 38.747 67.484 9.195 1.00 38.00 ? 160 VAL A N 1 ATOM 1019 C CA . VAL A 1 124 ? 38.958 68.029 7.861 1.00 41.27 ? 160 VAL A CA 1 ATOM 1020 C C . VAL A 1 124 ? 39.014 69.535 7.993 1.00 44.80 ? 160 VAL A C 1 ATOM 1021 O O . VAL A 1 124 ? 38.501 70.092 8.966 1.00 41.40 ? 160 VAL A O 1 ATOM 1022 C CB . VAL A 1 124 ? 37.817 67.654 6.882 1.00 47.35 ? 160 VAL A CB 1 ATOM 1023 C CG1 . VAL A 1 124 ? 37.733 66.140 6.708 1.00 44.36 ? 160 VAL A CG1 1 ATOM 1024 C CG2 . VAL A 1 124 ? 36.484 68.226 7.357 1.00 44.75 ? 160 VAL A CG2 1 ATOM 1025 N N . GLY A 1 125 ? 39.641 70.196 7.027 1.00 42.96 ? 161 GLY A N 1 ATOM 1026 C CA . GLY A 1 125 ? 39.764 71.643 7.071 1.00 44.21 ? 161 GLY A CA 1 ATOM 1027 C C . GLY A 1 125 ? 40.774 72.131 8.101 1.00 41.59 ? 161 GLY A C 1 ATOM 1028 O O . GLY A 1 125 ? 41.835 71.529 8.276 1.00 39.78 ? 161 GLY A O 1 ATOM 1029 N N . HIS A 1 126 ? 40.444 73.223 8.786 1.00 38.33 ? 162 HIS A N 1 ATOM 1030 C CA . HIS A 1 126 ? 41.383 73.845 9.716 1.00 39.48 ? 162 HIS A CA 1 ATOM 1031 C C . HIS A 1 126 ? 40.709 74.568 10.885 1.00 39.70 ? 162 HIS A C 1 ATOM 1032 O O . HIS A 1 126 ? 41.216 75.583 11.366 1.00 37.30 ? 162 HIS A O 1 ATOM 1033 C CB . HIS A 1 126 ? 42.301 74.805 8.963 1.00 40.55 ? 162 HIS A CB 1 ATOM 1034 C CG . HIS A 1 126 ? 41.568 75.764 8.076 1.00 44.34 ? 162 HIS A CG 1 ATOM 1035 N ND1 . HIS A 1 126 ? 42.105 76.259 6.907 1.00 52.13 ? 162 HIS A ND1 1 ATOM 1036 C CD2 . HIS A 1 126 ? 40.334 76.311 8.184 1.00 47.61 ? 162 HIS A CD2 1 ATOM 1037 C CE1 . HIS A 1 126 ? 41.235 77.076 6.337 1.00 52.40 ? 162 HIS A CE1 1 ATOM 1038 N NE2 . HIS A 1 126 ? 40.153 77.126 7.094 1.00 48.70 ? 162 HIS A NE2 1 ATOM 1039 N N . LYS A 1 127 ? 39.571 74.046 11.335 1.00 34.87 ? 163 LYS A N 1 ATOM 1040 C CA . LYS A 1 127 ? 38.965 74.528 12.567 1.00 37.14 ? 163 LYS A CA 1 ATOM 1041 C C . LYS A 1 127 ? 39.794 74.048 13.753 1.00 36.32 ? 163 LYS A C 1 ATOM 1042 O O . LYS A 1 127 ? 40.511 73.053 13.657 1.00 33.28 ? 163 LYS A O 1 ATOM 1043 C CB . LYS A 1 127 ? 37.536 74.016 12.716 1.00 35.12 ? 163 LYS A CB 1 ATOM 1044 C CG . LYS A 1 127 ? 36.572 74.540 11.684 1.00 39.85 ? 163 LYS A CG 1 ATOM 1045 C CD . LYS A 1 127 ? 35.181 74.017 11.984 1.00 37.84 ? 163 LYS A CD 1 ATOM 1046 C CE . LYS A 1 127 ? 34.210 74.391 10.881 1.00 39.53 ? 163 LYS A CE 1 ATOM 1047 N NZ . LYS A 1 127 ? 32.906 73.729 11.126 1.00 41.27 ? 163 LYS A NZ 1 ATOM 1048 N N . LEU A 1 128 ? 39.682 74.760 14.870 1.00 34.49 ? 164 LEU A N 1 ATOM 1049 C CA . LEU A 1 128 ? 40.407 74.431 16.089 1.00 32.33 ? 164 LEU A CA 1 ATOM 1050 C C . LEU A 1 128 ? 39.439 74.432 17.251 1.00 37.50 ? 164 LEU A C 1 ATOM 1051 O O . LEU A 1 128 ? 38.590 75.322 17.354 1.00 34.74 ? 164 LEU A O 1 ATOM 1052 C CB . LEU A 1 128 ? 41.479 75.478 16.373 1.00 32.65 ? 164 LEU A CB 1 ATOM 1053 C CG . LEU A 1 128 ? 42.830 75.346 15.684 1.00 39.12 ? 164 LEU A CG 1 ATOM 1054 C CD1 . LEU A 1 128 ? 43.625 76.635 15.830 1.00 40.97 ? 164 LEU A CD1 1 ATOM 1055 C CD2 . LEU A 1 128 ? 43.607 74.190 16.254 1.00 35.94 ? 164 LEU A CD2 1 ATOM 1056 N N . ALA A 1 129 ? 39.557 73.430 18.119 1.00 33.42 ? 165 ALA A N 1 ATOM 1057 C CA . ALA A 1 129 ? 38.872 73.452 19.403 1.00 33.15 ? 165 ALA A CA 1 ATOM 1058 C C . ALA A 1 129 ? 39.958 73.358 20.453 1.00 32.81 ? 165 ALA A C 1 ATOM 1059 O O . ALA A 1 129 ? 40.864 72.542 20.334 1.00 33.64 ? 165 ALA A O 1 ATOM 1060 C CB . ALA A 1 129 ? 37.925 72.288 19.529 1.00 33.21 ? 165 ALA A CB 1 ATOM 1061 N N . TYR A 1 130 ? 39.903 74.213 21.461 1.00 34.66 ? 166 TYR A N 1 ATOM 1062 C CA . TYR A 1 130 ? 40.867 74.118 22.544 1.00 32.83 ? 166 TYR A CA 1 ATOM 1063 C C . TYR A 1 130 ? 40.209 74.316 23.900 1.00 32.23 ? 166 TYR A C 1 ATOM 1064 O O . TYR A 1 130 ? 39.081 74.781 23.991 1.00 31.82 ? 166 TYR A O 1 ATOM 1065 C CB . TYR A 1 130 ? 42.025 75.093 22.333 1.00 32.34 ? 166 TYR A CB 1 ATOM 1066 C CG . TYR A 1 130 ? 41.666 76.557 22.396 1.00 34.56 ? 166 TYR A CG 1 ATOM 1067 C CD1 . TYR A 1 130 ? 41.590 77.219 23.616 1.00 33.86 ? 166 TYR A CD1 1 ATOM 1068 C CD2 . TYR A 1 130 ? 41.439 77.292 21.230 1.00 36.66 ? 166 TYR A CD2 1 ATOM 1069 C CE1 . TYR A 1 130 ? 41.281 78.569 23.679 1.00 32.89 ? 166 TYR A CE1 1 ATOM 1070 C CE2 . TYR A 1 130 ? 41.131 78.648 21.285 1.00 34.51 ? 166 TYR A CE2 1 ATOM 1071 C CZ . TYR A 1 130 ? 41.056 79.276 22.509 1.00 35.36 ? 166 TYR A CZ 1 ATOM 1072 O OH . TYR A 1 130 ? 40.749 80.612 22.578 1.00 38.40 ? 166 TYR A OH 1 ATOM 1073 N N . VAL A 1 131 ? 40.916 73.942 24.954 1.00 30.42 ? 167 VAL A N 1 ATOM 1074 C CA . VAL A 1 131 ? 40.385 74.077 26.299 1.00 30.23 ? 167 VAL A CA 1 ATOM 1075 C C . VAL A 1 131 ? 41.340 74.939 27.104 1.00 31.08 ? 167 VAL A C 1 ATOM 1076 O O . VAL A 1 131 ? 42.560 74.783 27.035 1.00 30.89 ? 167 VAL A O 1 ATOM 1077 C CB . VAL A 1 131 ? 40.179 72.708 26.954 1.00 31.42 ? 167 VAL A CB 1 ATOM 1078 C CG1 . VAL A 1 131 ? 39.684 72.857 28.408 1.00 30.07 ? 167 VAL A CG1 1 ATOM 1079 C CG2 . VAL A 1 131 ? 39.204 71.883 26.113 1.00 29.40 ? 167 VAL A CG2 1 ATOM 1080 N N . TRP A 1 132 ? 40.777 75.878 27.846 1.00 31.02 ? 168 TRP A N 1 ATOM 1081 C CA . TRP A 1 132 ? 41.580 76.818 28.591 1.00 30.46 ? 168 TRP A CA 1 ATOM 1082 C C . TRP A 1 132 ? 40.785 77.202 29.829 1.00 34.02 ? 168 TRP A C 1 ATOM 1083 O O . TRP A 1 132 ? 39.610 77.550 29.724 1.00 30.51 ? 168 TRP A O 1 ATOM 1084 C CB . TRP A 1 132 ? 41.893 78.034 27.722 1.00 29.41 ? 168 TRP A CB 1 ATOM 1085 C CG . TRP A 1 132 ? 42.712 79.069 28.433 1.00 37.09 ? 168 TRP A CG 1 ATOM 1086 C CD1 . TRP A 1 132 ? 44.019 78.964 28.812 1.00 37.01 ? 168 TRP A CD1 1 ATOM 1087 C CD2 . TRP A 1 132 ? 42.275 80.368 28.848 1.00 38.76 ? 168 TRP A CD2 1 ATOM 1088 N NE1 . TRP A 1 132 ? 44.421 80.120 29.444 1.00 41.48 ? 168 TRP A NE1 1 ATOM 1089 C CE2 . TRP A 1 132 ? 43.368 80.998 29.473 1.00 40.42 ? 168 TRP A CE2 1 ATOM 1090 C CE3 . TRP A 1 132 ? 41.064 81.064 28.741 1.00 42.68 ? 168 TRP A CE3 1 ATOM 1091 C CZ2 . TRP A 1 132 ? 43.288 82.287 29.997 1.00 46.28 ? 168 TRP A CZ2 1 ATOM 1092 C CZ3 . TRP A 1 132 ? 40.985 82.348 29.262 1.00 46.67 ? 168 TRP A CZ3 1 ATOM 1093 C CH2 . TRP A 1 132 ? 42.091 82.943 29.883 1.00 48.81 ? 168 TRP A CH2 1 ATOM 1094 N N . ASN A 1 133 ? 41.411 77.092 30.999 1.00 31.80 ? 169 ASN A N 1 ATOM 1095 C CA . ASN A 1 133 ? 40.708 77.309 32.259 1.00 34.11 ? 169 ASN A CA 1 ATOM 1096 C C . ASN A 1 133 ? 39.458 76.442 32.353 1.00 33.92 ? 169 ASN A C 1 ATOM 1097 O O . ASN A 1 133 ? 38.430 76.875 32.872 1.00 32.49 ? 169 ASN A O 1 ATOM 1098 C CB . ASN A 1 133 ? 40.330 78.782 32.434 1.00 33.85 ? 169 ASN A CB 1 ATOM 1099 C CG . ASN A 1 133 ? 41.530 79.663 32.750 1.00 44.96 ? 169 ASN A CG 1 ATOM 1100 O OD1 . ASN A 1 133 ? 42.610 79.174 33.097 1.00 46.20 ? 169 ASN A OD1 1 ATOM 1101 N ND2 . ASN A 1 133 ? 41.342 80.976 32.635 1.00 50.23 ? 169 ASN A ND2 1 ATOM 1102 N N . ASN A 1 134 ? 39.551 75.222 31.831 1.00 31.13 ? 170 ASN A N 1 ATOM 1103 C CA . ASN A 1 134 ? 38.479 74.236 31.948 1.00 30.60 ? 170 ASN A CA 1 ATOM 1104 C C . ASN A 1 134 ? 37.239 74.546 31.114 1.00 31.06 ? 170 ASN A C 1 ATOM 1105 O O . ASN A 1 134 ? 36.211 73.898 31.282 1.00 32.89 ? 170 ASN A O 1 ATOM 1106 C CB . ASN A 1 134 ? 38.073 74.024 33.411 1.00 26.95 ? 170 ASN A CB 1 ATOM 1107 C CG . ASN A 1 134 ? 39.139 73.303 34.227 1.00 27.47 ? 170 ASN A CG 1 ATOM 1108 O OD1 . ASN A 1 134 ? 40.333 73.551 34.074 1.00 33.47 ? 170 ASN A OD1 1 ATOM 1109 N ND2 . ASN A 1 134 ? 38.704 72.429 35.121 1.00 29.01 ? 170 ASN A ND2 1 ATOM 1110 N N . ASP A 1 135 ? 37.331 75.535 30.229 1.00 31.30 ? 171 ASP A N 1 ATOM 1111 C CA . ASP A 1 135 ? 36.263 75.797 29.252 1.00 30.44 ? 171 ASP A CA 1 ATOM 1112 C C . ASP A 1 135 ? 36.712 75.570 27.807 1.00 31.18 ? 171 ASP A C 1 ATOM 1113 O O . ASP A 1 135 ? 37.889 75.708 27.477 1.00 31.54 ? 171 ASP A O 1 ATOM 1114 C CB . ASP A 1 135 ? 35.771 77.232 29.349 1.00 31.57 ? 171 ASP A CB 1 ATOM 1115 C CG . ASP A 1 135 ? 34.944 77.483 30.582 1.00 35.33 ? 171 ASP A CG 1 ATOM 1116 O OD1 . ASP A 1 135 ? 33.985 76.713 30.842 1.00 33.36 ? 171 ASP A OD1 1 ATOM 1117 O OD2 . ASP A 1 135 ? 35.256 78.468 31.282 1.00 38.69 ? 171 ASP A OD2 1 ATOM 1118 N N . ILE A 1 136 ? 35.745 75.275 26.944 1.00 31.86 ? 172 ILE A N 1 ATOM 1119 C CA . ILE A 1 136 ? 36.004 74.971 25.543 1.00 33.51 ? 172 ILE A CA 1 ATOM 1120 C C . ILE A 1 136 ? 35.802 76.194 24.664 1.00 34.91 ? 172 ILE A C 1 ATOM 1121 O O . ILE A 1 136 ? 34.825 76.922 24.825 1.00 34.60 ? 172 ILE A O 1 ATOM 1122 C CB . ILE A 1 136 ? 35.045 73.874 25.055 1.00 31.62 ? 172 ILE A CB 1 ATOM 1123 C CG1 . ILE A 1 136 ? 35.254 72.602 25.885 1.00 30.98 ? 172 ILE A CG1 1 ATOM 1124 C CG2 . ILE A 1 136 ? 35.235 73.612 23.555 1.00 34.03 ? 172 ILE A CG2 1 ATOM 1125 C CD1 . ILE A 1 136 ? 34.148 71.588 25.749 1.00 31.96 ? 172 ILE A CD1 1 ATOM 1126 N N . TYR A 1 137 ? 36.723 76.397 23.729 1.00 33.80 ? 173 TYR A N 1 ATOM 1127 C CA . TYR A 1 137 ? 36.651 77.477 22.749 1.00 31.99 ? 173 TYR A CA 1 ATOM 1128 C C . TYR A 1 137 ? 36.794 76.896 21.334 1.00 35.60 ? 173 TYR A C 1 ATOM 1129 O O . TYR A 1 137 ? 37.414 75.840 21.149 1.00 33.18 ? 173 TYR A O 1 ATOM 1130 C CB . TYR A 1 137 ? 37.776 78.488 23.012 1.00 33.37 ? 173 TYR A CB 1 ATOM 1131 C CG . TYR A 1 137 ? 37.681 79.196 24.354 1.00 35.10 ? 173 TYR A CG 1 ATOM 1132 C CD1 . TYR A 1 137 ? 38.089 78.567 25.528 1.00 34.86 ? 173 TYR A CD1 1 ATOM 1133 C CD2 . TYR A 1 137 ? 37.187 80.495 24.447 1.00 37.58 ? 173 TYR A CD2 1 ATOM 1134 C CE1 . TYR A 1 137 ? 37.998 79.210 26.761 1.00 35.61 ? 173 TYR A CE1 1 ATOM 1135 C CE2 . TYR A 1 137 ? 37.102 81.149 25.674 1.00 36.58 ? 173 TYR A CE2 1 ATOM 1136 C CZ . TYR A 1 137 ? 37.502 80.497 26.825 1.00 35.11 ? 173 TYR A CZ 1 ATOM 1137 O OH . TYR A 1 137 ? 37.416 81.133 28.051 1.00 37.14 ? 173 TYR A OH 1 ATOM 1138 N N . VAL A 1 138 ? 36.225 77.575 20.338 1.00 35.78 ? 174 VAL A N 1 ATOM 1139 C CA . VAL A 1 138 ? 36.369 77.152 18.942 1.00 36.07 ? 174 VAL A CA 1 ATOM 1140 C C . VAL A 1 138 ? 36.817 78.299 18.035 1.00 37.46 ? 174 VAL A C 1 ATOM 1141 O O . VAL A 1 138 ? 36.183 79.350 18.025 1.00 38.41 ? 174 VAL A O 1 ATOM 1142 C CB . VAL A 1 138 ? 35.042 76.602 18.394 1.00 35.62 ? 174 VAL A CB 1 ATOM 1143 C CG1 . VAL A 1 138 ? 35.159 76.307 16.914 1.00 36.34 ? 174 VAL A CG1 1 ATOM 1144 C CG2 . VAL A 1 138 ? 34.631 75.362 19.167 1.00 34.39 ? 174 VAL A CG2 1 ATOM 1145 N N . LYS A 1 139 ? 37.904 78.101 17.285 1.00 36.63 ? 175 LYS A N 1 ATOM 1146 C CA . LYS A 1 139 ? 38.299 79.033 16.226 1.00 36.85 ? 175 LYS A CA 1 ATOM 1147 C C . LYS A 1 139 ? 37.907 78.444 14.873 1.00 42.25 ? 175 LYS A C 1 ATOM 1148 O O . LYS A 1 139 ? 38.324 77.340 14.533 1.00 39.08 ? 175 LYS A O 1 ATOM 1149 C CB . LYS A 1 139 ? 39.817 79.297 16.228 1.00 38.68 ? 175 LYS A CB 1 ATOM 1150 C CG . LYS A 1 139 ? 40.329 80.303 17.254 1.00 40.78 ? 175 LYS A CG 1 ATOM 1151 C CD . LYS A 1 139 ? 41.802 80.657 17.006 1.00 39.00 ? 175 LYS A CD 1 ATOM 1152 N N . ILE A 1 140 ? 37.114 79.175 14.097 1.00 42.15 ? 176 ILE A N 1 ATOM 1153 C CA . ILE A 1 140 ? 36.772 78.738 12.747 1.00 41.28 ? 176 ILE A CA 1 ATOM 1154 C C . ILE A 1 140 ? 37.966 78.947 11.837 1.00 42.52 ? 176 ILE A C 1 ATOM 1155 O O . ILE A 1 140 ? 38.294 78.090 11.031 1.00 42.34 ? 176 ILE A O 1 ATOM 1156 C CB . ILE A 1 140 ? 35.594 79.524 12.186 1.00 41.48 ? 176 ILE A CB 1 ATOM 1157 C CG1 . ILE A 1 140 ? 34.391 79.412 13.121 1.00 43.11 ? 176 ILE A CG1 1 ATOM 1158 C CG2 . ILE A 1 140 ? 35.262 79.050 10.787 1.00 44.63 ? 176 ILE A CG2 1 ATOM 1159 C CD1 . ILE A 1 140 ? 33.876 78.010 13.303 1.00 42.41 ? 176 ILE A CD1 1 ATOM 1160 N N . GLU A 1 141 ? 38.618 80.095 11.982 1.00 42.57 ? 177 GLU A N 1 ATOM 1161 C CA . GLU A 1 141 ? 39.840 80.381 11.246 1.00 44.38 ? 177 GLU A CA 1 ATOM 1162 C C . GLU A 1 141 ? 40.929 80.740 12.241 1.00 43.42 ? 177 GLU A C 1 ATOM 1163 O O . GLU A 1 141 ? 40.656 81.363 13.262 1.00 41.57 ? 177 GLU A O 1 ATOM 1164 C CB . GLU A 1 141 ? 39.625 81.542 10.265 1.00 47.36 ? 177 GLU A CB 1 ATOM 1165 C CG . GLU A 1 141 ? 38.409 81.388 9.355 1.00 46.49 ? 177 GLU A CG 1 ATOM 1166 C CD . GLU A 1 141 ? 38.632 80.378 8.252 1.00 53.84 ? 177 GLU A CD 1 ATOM 1167 O OE1 . GLU A 1 141 ? 39.802 79.981 8.044 1.00 53.67 ? 177 GLU A OE1 1 ATOM 1168 O OE2 . GLU A 1 141 ? 37.640 79.987 7.596 1.00 55.20 ? 177 GLU A OE2 1 ATOM 1169 N N . PRO A 1 142 ? 42.171 80.347 11.948 1.00 40.03 ? 178 PRO A N 1 ATOM 1170 C CA . PRO A 1 142 ? 43.274 80.586 12.884 1.00 43.70 ? 178 PRO A CA 1 ATOM 1171 C C . PRO A 1 142 ? 43.528 82.054 13.241 1.00 48.36 ? 178 PRO A C 1 ATOM 1172 O O . PRO A 1 142 ? 44.211 82.298 14.236 1.00 47.28 ? 178 PRO A O 1 ATOM 1173 C CB . PRO A 1 142 ? 44.487 79.991 12.161 1.00 43.51 ? 178 PRO A CB 1 ATOM 1174 C CG . PRO A 1 142 ? 43.901 78.946 11.256 1.00 43.88 ? 178 PRO A CG 1 ATOM 1175 C CD . PRO A 1 142 ? 42.570 79.492 10.816 1.00 43.44 ? 178 PRO A CD 1 ATOM 1176 N N . ASN A 1 143 ? 43.006 83.009 12.477 1.00 46.47 ? 179 ASN A N 1 ATOM 1177 C CA . ASN A 1 143 ? 43.282 84.420 12.775 1.00 48.62 ? 179 ASN A CA 1 ATOM 1178 C C . ASN A 1 143 ? 42.044 85.225 13.174 1.00 48.22 ? 179 ASN A C 1 ATOM 1179 C CB . ASN A 1 143 ? 44.012 85.095 11.608 1.00 53.23 ? 179 ASN A CB 1 ATOM 1180 C CG . ASN A 1 143 ? 43.113 85.311 10.397 1.00 55.84 ? 179 ASN A CG 1 ATOM 1181 O OD1 . ASN A 1 143 ? 42.076 84.661 10.247 1.00 50.65 ? 179 ASN A OD1 1 ATOM 1182 N ND2 . ASN A 1 143 ? 43.516 86.228 9.523 1.00 53.72 ? 179 ASN A ND2 1 ATOM 1183 N N . LEU A 1 144 ? 40.961 84.503 13.444 1.00 47.87 ? 180 LEU A N 1 ATOM 1184 C CA . LEU A 1 144 ? 39.711 85.104 13.895 1.00 47.86 ? 180 LEU A CA 1 ATOM 1185 C C . LEU A 1 144 ? 39.459 84.792 15.366 1.00 48.83 ? 180 LEU A C 1 ATOM 1186 O O . LEU A 1 144 ? 39.965 83.794 15.890 1.00 47.67 ? 180 LEU A O 1 ATOM 1187 C CB . LEU A 1 144 ? 38.541 84.597 13.053 1.00 48.06 ? 180 LEU A CB 1 ATOM 1188 C CG . LEU A 1 144 ? 38.621 84.958 11.572 1.00 48.92 ? 180 LEU A CG 1 ATOM 1189 C CD1 . LEU A 1 144 ? 37.326 84.599 10.877 1.00 47.93 ? 180 LEU A CD1 1 ATOM 1190 C CD2 . LEU A 1 144 ? 38.912 86.440 11.440 1.00 53.35 ? 180 LEU A CD2 1 ATOM 1191 N N . PRO A 1 145 ? 38.665 85.641 16.041 1.00 48.58 ? 181 PRO A N 1 ATOM 1192 C CA . PRO A 1 145 ? 38.418 85.435 17.471 1.00 49.94 ? 181 PRO A CA 1 ATOM 1193 C C . PRO A 1 145 ? 37.750 84.086 17.711 1.00 45.28 ? 181 PRO A C 1 ATOM 1194 O O . PRO A 1 145 ? 37.066 83.564 16.836 1.00 40.39 ? 181 PRO A O 1 ATOM 1195 C CB . PRO A 1 145 ? 37.454 86.577 17.837 1.00 50.35 ? 181 PRO A CB 1 ATOM 1196 C CG . PRO A 1 145 ? 37.595 87.581 16.731 1.00 50.88 ? 181 PRO A CG 1 ATOM 1197 C CD . PRO A 1 145 ? 37.902 86.782 15.505 1.00 51.21 ? 181 PRO A CD 1 ATOM 1198 N N . SER A 1 146 ? 37.956 83.517 18.888 1.00 40.27 ? 182 SER A N 1 ATOM 1199 C CA . SER A 1 146 ? 37.344 82.239 19.175 1.00 40.94 ? 182 SER A CA 1 ATOM 1200 C C . SER A 1 146 ? 35.948 82.451 19.735 1.00 41.68 ? 182 SER A C 1 ATOM 1201 O O . SER A 1 146 ? 35.617 83.526 20.228 1.00 42.57 ? 182 SER A O 1 ATOM 1202 C CB . SER A 1 146 ? 38.208 81.424 20.139 1.00 37.56 ? 182 SER A CB 1 ATOM 1203 O OG . SER A 1 146 ? 38.344 82.084 21.377 1.00 48.25 ? 182 SER A OG 1 ATOM 1204 N N . TYR A 1 147 ? 35.129 81.419 19.631 1.00 38.36 ? 183 TYR A N 1 ATOM 1205 C CA . TYR A 1 147 ? 33.787 81.432 20.179 1.00 37.61 ? 183 TYR A CA 1 ATOM 1206 C C . TYR A 1 147 ? 33.839 80.626 21.471 1.00 36.85 ? 183 TYR A C 1 ATOM 1207 O O . TYR A 1 147 ? 34.272 79.480 21.458 1.00 33.38 ? 183 TYR A O 1 ATOM 1208 C CB . TYR A 1 147 ? 32.818 80.763 19.199 1.00 40.36 ? 183 TYR A CB 1 ATOM 1209 C CG . TYR A 1 147 ? 32.665 81.456 17.854 1.00 41.65 ? 183 TYR A CG 1 ATOM 1210 C CD1 . TYR A 1 147 ? 33.535 81.190 16.807 1.00 47.95 ? 183 TYR A CD1 1 ATOM 1211 C CD2 . TYR A 1 147 ? 31.642 82.365 17.630 1.00 48.77 ? 183 TYR A CD2 1 ATOM 1212 C CE1 . TYR A 1 147 ? 33.395 81.819 15.572 1.00 45.60 ? 183 TYR A CE1 1 ATOM 1213 C CE2 . TYR A 1 147 ? 31.495 82.998 16.403 1.00 51.40 ? 183 TYR A CE2 1 ATOM 1214 C CZ . TYR A 1 147 ? 32.373 82.720 15.376 1.00 49.60 ? 183 TYR A CZ 1 ATOM 1215 O OH . TYR A 1 147 ? 32.229 83.345 14.150 1.00 49.73 ? 183 TYR A OH 1 ATOM 1216 N N . ARG A 1 148 ? 33.414 81.213 22.587 1.00 34.91 ? 184 ARG A N 1 ATOM 1217 C CA . ARG A 1 148 ? 33.404 80.474 23.844 1.00 33.74 ? 184 ARG A CA 1 ATOM 1218 C C . ARG A 1 148 ? 32.180 79.560 23.914 1.00 36.82 ? 184 ARG A C 1 ATOM 1219 O O . ARG A 1 148 ? 31.048 80.009 23.747 1.00 37.94 ? 184 ARG A O 1 ATOM 1220 C CB . ARG A 1 148 ? 33.466 81.438 25.033 1.00 36.72 ? 184 ARG A CB 1 ATOM 1221 C CG . ARG A 1 148 ? 33.459 80.764 26.390 1.00 39.17 ? 184 ARG A CG 1 ATOM 1222 C CD . ARG A 1 148 ? 33.835 81.766 27.483 1.00 38.00 ? 184 ARG A CD 1 ATOM 1223 N NE . ARG A 1 148 ? 33.880 81.154 28.804 1.00 37.28 ? 184 ARG A NE 1 ATOM 1224 C CZ . ARG A 1 148 ? 34.294 81.789 29.898 1.00 39.99 ? 184 ARG A CZ 1 ATOM 1225 N NH1 . ARG A 1 148 ? 34.711 83.047 29.815 1.00 36.42 ? 184 ARG A NH1 1 ATOM 1226 N NH2 . ARG A 1 148 ? 34.306 81.170 31.069 1.00 32.87 ? 184 ARG A NH2 1 ATOM 1227 N N . ILE A 1 149 ? 32.420 78.270 24.138 1.00 36.79 ? 185 ILE A N 1 ATOM 1228 C CA . ILE A 1 149 ? 31.358 77.261 24.136 1.00 35.21 ? 185 ILE A CA 1 ATOM 1229 C C . ILE A 1 149 ? 30.782 76.981 25.526 1.00 37.16 ? 185 ILE A C 1 ATOM 1230 O O . ILE A 1 149 ? 29.572 76.770 25.685 1.00 36.67 ? 185 ILE A O 1 ATOM 1231 C CB . ILE A 1 149 ? 31.862 75.924 23.540 1.00 34.93 ? 185 ILE A CB 1 ATOM 1232 C CG1 . ILE A 1 149 ? 32.333 76.125 22.099 1.00 39.16 ? 185 ILE A CG1 1 ATOM 1233 C CG2 . ILE A 1 149 ? 30.780 74.858 23.630 1.00 36.25 ? 185 ILE A CG2 1 ATOM 1234 C CD1 . ILE A 1 149 ? 31.294 76.769 21.209 1.00 35.63 ? 185 ILE A CD1 1 ATOM 1235 N N . THR A 1 150 ? 31.646 76.957 26.538 1.00 36.94 ? 186 THR A N 1 ATOM 1236 C CA . THR A 1 150 ? 31.174 76.701 27.894 1.00 35.18 ? 186 THR A CA 1 ATOM 1237 C C . THR A 1 150 ? 31.626 77.800 28.849 1.00 36.35 ? 186 THR A C 1 ATOM 1238 O O . THR A 1 150 ? 32.650 78.452 28.627 1.00 35.04 ? 186 THR A O 1 ATOM 1239 C CB . THR A 1 150 ? 31.640 75.327 28.414 1.00 35.33 ? 186 THR A CB 1 ATOM 1240 O OG1 . THR A 1 150 ? 33.072 75.306 28.517 1.00 34.09 ? 186 THR A OG1 1 ATOM 1241 C CG2 . THR A 1 150 ? 31.172 74.224 27.486 1.00 33.90 ? 186 THR A CG2 1 ATOM 1242 N N . TRP A 1 151 ? 30.861 77.993 29.915 1.00 37.78 ? 187 TRP A N 1 ATOM 1243 C CA . TRP A 1 151 ? 31.139 79.066 30.859 1.00 38.13 ? 187 TRP A CA 1 ATOM 1244 C C . TRP A 1 151 ? 31.228 78.532 32.289 1.00 37.66 ? 187 TRP A C 1 ATOM 1245 O O . TRP A 1 151 ? 31.383 79.304 33.230 1.00 41.32 ? 187 TRP A O 1 ATOM 1246 C CB . TRP A 1 151 ? 30.048 80.143 30.768 1.00 39.88 ? 187 TRP A CB 1 ATOM 1247 C CG . TRP A 1 151 ? 29.978 80.854 29.436 1.00 42.67 ? 187 TRP A CG 1 ATOM 1248 C CD1 . TRP A 1 151 ? 29.393 80.396 28.286 1.00 45.05 ? 187 TRP A CD1 1 ATOM 1249 C CD2 . TRP A 1 151 ? 30.508 82.150 29.125 1.00 44.23 ? 187 TRP A CD2 1 ATOM 1250 N NE1 . TRP A 1 151 ? 29.535 81.324 27.278 1.00 45.88 ? 187 TRP A NE1 1 ATOM 1251 C CE2 . TRP A 1 151 ? 30.216 82.409 27.768 1.00 45.67 ? 187 TRP A CE2 1 ATOM 1252 C CE3 . TRP A 1 151 ? 31.200 83.119 29.864 1.00 45.52 ? 187 TRP A CE3 1 ATOM 1253 C CZ2 . TRP A 1 151 ? 30.588 83.598 27.136 1.00 48.04 ? 187 TRP A CZ2 1 ATOM 1254 C CZ3 . TRP A 1 151 ? 31.573 84.300 29.232 1.00 46.97 ? 187 TRP A CZ3 1 ATOM 1255 C CH2 . TRP A 1 151 ? 31.268 84.527 27.882 1.00 49.08 ? 187 TRP A CH2 1 ATOM 1256 N N . THR A 1 152 ? 31.139 77.217 32.453 1.00 36.34 ? 188 THR A N 1 ATOM 1257 C CA . THR A 1 152 ? 31.024 76.624 33.787 1.00 33.98 ? 188 THR A CA 1 ATOM 1258 C C . THR A 1 152 ? 32.337 76.093 34.350 1.00 34.56 ? 188 THR A C 1 ATOM 1259 O O . THR A 1 152 ? 32.372 75.580 35.470 1.00 33.81 ? 188 THR A O 1 ATOM 1260 C CB . THR A 1 152 ? 30.055 75.455 33.750 1.00 38.25 ? 188 THR A CB 1 ATOM 1261 O OG1 . THR A 1 152 ? 30.385 74.620 32.626 1.00 37.38 ? 188 THR A OG1 1 ATOM 1262 C CG2 . THR A 1 152 ? 28.625 75.961 33.586 1.00 39.43 ? 188 THR A CG2 1 ATOM 1263 N N . GLY A 1 153 ? 33.410 76.195 33.570 1.00 33.37 ? 189 GLY A N 1 ATOM 1264 C CA . GLY A 1 153 ? 34.677 75.606 33.960 1.00 32.92 ? 189 GLY A CA 1 ATOM 1265 C C . GLY A 1 153 ? 35.272 76.192 35.226 1.00 30.53 ? 189 GLY A C 1 ATOM 1266 O O . GLY A 1 153 ? 35.307 77.404 35.404 1.00 31.68 ? 189 GLY A O 1 ATOM 1267 N N . LYS A 1 154 ? 35.776 75.326 36.092 1.00 32.44 ? 190 LYS A N 1 ATOM 1268 C CA . LYS A 1 154 ? 36.311 75.761 37.376 1.00 32.13 ? 190 LYS A CA 1 ATOM 1269 C C . LYS A 1 154 ? 37.344 74.755 37.856 1.00 32.95 ? 190 LYS A C 1 ATOM 1270 O O . LYS A 1 154 ? 37.074 73.563 37.918 1.00 31.09 ? 190 LYS A O 1 ATOM 1271 C CB . LYS A 1 154 ? 35.172 75.884 38.389 1.00 32.98 ? 190 LYS A CB 1 ATOM 1272 C CG . LYS A 1 154 ? 35.578 76.478 39.729 1.00 41.71 ? 190 LYS A CG 1 ATOM 1273 C CD . LYS A 1 154 ? 34.380 76.567 40.676 1.00 47.97 ? 190 LYS A CD 1 ATOM 1274 C CE . LYS A 1 154 ? 34.760 77.280 41.971 1.00 57.07 ? 190 LYS A CE 1 ATOM 1275 N NZ . LYS A 1 154 ? 33.636 78.116 42.476 1.00 66.08 ? 190 LYS A NZ 1 ATOM 1276 N N . GLU A 1 155 ? 38.523 75.244 38.212 1.00 35.25 ? 191 GLU A N 1 ATOM 1277 C CA . GLU A 1 155 ? 39.639 74.373 38.556 1.00 37.83 ? 191 GLU A CA 1 ATOM 1278 C C . GLU A 1 155 ? 39.273 73.334 39.614 1.00 38.27 ? 191 GLU A C 1 ATOM 1279 O O . GLU A 1 155 ? 38.742 73.671 40.683 1.00 33.55 ? 191 GLU A O 1 ATOM 1280 C CB . GLU A 1 155 ? 40.851 75.196 39.003 1.00 43.31 ? 191 GLU A CB 1 ATOM 1281 C CG . GLU A 1 155 ? 42.135 74.381 39.062 1.00 47.77 ? 191 GLU A CG 1 ATOM 1282 C CD . GLU A 1 155 ? 43.353 75.203 39.469 1.00 60.96 ? 191 GLU A CD 1 ATOM 1283 O OE1 . GLU A 1 155 ? 43.187 76.402 39.794 1.00 62.91 ? 191 GLU A OE1 1 ATOM 1284 O OE2 . GLU A 1 155 ? 44.476 74.643 39.468 1.00 62.47 ? 191 GLU A OE2 1 ATOM 1285 N N . ASP A 1 156 ? 39.544 72.067 39.297 1.00 32.48 ? 192 ASP A N 1 ATOM 1286 C CA . ASP A 1 156 ? 39.316 70.953 40.222 1.00 33.51 ? 192 ASP A CA 1 ATOM 1287 C C . ASP A 1 156 ? 37.851 70.621 40.477 1.00 34.03 ? 192 ASP A C 1 ATOM 1288 O O . ASP A 1 156 ? 37.552 69.746 41.296 1.00 34.61 ? 192 ASP A O 1 ATOM 1289 C CB . ASP A 1 156 ? 40.003 71.205 41.576 1.00 38.02 ? 192 ASP A CB 1 ATOM 1290 C CG . ASP A 1 156 ? 41.519 71.231 41.469 1.00 41.84 ? 192 ASP A CG 1 ATOM 1291 O OD1 . ASP A 1 156 ? 42.080 70.496 40.630 1.00 41.78 ? 192 ASP A OD1 1 ATOM 1292 O OD2 . ASP A 1 156 ? 42.157 71.987 42.230 1.00 46.26 ? 192 ASP A OD2 1 ATOM 1293 N N . ILE A 1 157 ? 36.936 71.311 39.803 1.00 31.79 ? 193 ILE A N 1 ATOM 1294 C CA . ILE A 1 157 ? 35.510 71.079 40.061 1.00 31.83 ? 193 ILE A CA 1 ATOM 1295 C C . ILE A 1 157 ? 34.694 70.746 38.802 1.00 30.11 ? 193 ILE A C 1 ATOM 1296 O O . ILE A 1 157 ? 34.091 69.669 38.718 1.00 32.06 ? 193 ILE A O 1 ATOM 1297 C CB . ILE A 1 157 ? 34.886 72.257 40.828 1.00 29.25 ? 193 ILE A CB 1 ATOM 1298 C CG1 . ILE A 1 157 ? 35.629 72.455 42.152 1.00 37.13 ? 193 ILE A CG1 1 ATOM 1299 C CG2 . ILE A 1 157 ? 33.422 71.994 41.093 1.00 28.42 ? 193 ILE A CG2 1 ATOM 1300 C CD1 . ILE A 1 157 ? 35.247 73.723 42.880 1.00 45.14 ? 193 ILE A CD1 1 ATOM 1301 N N . ILE A 1 158 ? 34.683 71.659 37.832 1.00 27.13 ? 194 ILE A N 1 ATOM 1302 C CA . ILE A 1 158 ? 33.985 71.430 36.565 1.00 29.40 ? 194 ILE A CA 1 ATOM 1303 C C . ILE A 1 158 ? 34.978 71.387 35.406 1.00 28.83 ? 194 ILE A C 1 ATOM 1304 O O . ILE A 1 158 ? 35.720 72.350 35.187 1.00 27.82 ? 194 ILE A O 1 ATOM 1305 C CB . ILE A 1 158 ? 32.944 72.529 36.252 1.00 30.03 ? 194 ILE A CB 1 ATOM 1306 C CG1 . ILE A 1 158 ? 32.002 72.738 37.443 1.00 29.97 ? 194 ILE A CG1 1 ATOM 1307 C CG2 . ILE A 1 158 ? 32.138 72.154 35.003 1.00 26.57 ? 194 ILE A CG2 1 ATOM 1308 C CD1 . ILE A 1 158 ? 31.329 71.480 37.881 1.00 28.10 ? 194 ILE A CD1 1 ATOM 1309 N N . TYR A 1 159 ? 34.998 70.271 34.677 1.00 25.89 ? 195 TYR A N 1 ATOM 1310 C CA . TYR A 1 159 ? 35.897 70.122 33.535 1.00 28.26 ? 195 TYR A CA 1 ATOM 1311 C C . TYR A 1 159 ? 35.073 69.987 32.262 1.00 27.30 ? 195 TYR A C 1 ATOM 1312 O O . TYR A 1 159 ? 34.327 69.016 32.106 1.00 27.57 ? 195 TYR A O 1 ATOM 1313 C CB . TYR A 1 159 ? 36.756 68.861 33.655 1.00 29.22 ? 195 TYR A CB 1 ATOM 1314 C CG . TYR A 1 159 ? 37.543 68.663 34.934 1.00 29.27 ? 195 TYR A CG 1 ATOM 1315 C CD1 . TYR A 1 159 ? 36.898 68.355 36.118 1.00 29.03 ? 195 TYR A CD1 1 ATOM 1316 C CD2 . TYR A 1 159 ? 38.938 68.722 34.938 1.00 29.06 ? 195 TYR A CD2 1 ATOM 1317 C CE1 . TYR A 1 159 ? 37.608 68.135 37.278 1.00 33.36 ? 195 TYR A CE1 1 ATOM 1318 C CE2 . TYR A 1 159 ? 39.660 68.507 36.098 1.00 27.03 ? 195 TYR A CE2 1 ATOM 1319 C CZ . TYR A 1 159 ? 38.983 68.213 37.269 1.00 33.33 ? 195 TYR A CZ 1 ATOM 1320 O OH . TYR A 1 159 ? 39.668 68.002 38.450 1.00 36.28 ? 195 TYR A OH 1 ATOM 1321 N N . ASN A 1 160 ? 35.191 70.953 31.359 1.00 28.70 ? 196 ASN A N 1 ATOM 1322 C CA . ASN A 1 160 ? 34.531 70.852 30.056 1.00 30.60 ? 196 ASN A CA 1 ATOM 1323 C C . ASN A 1 160 ? 35.530 70.509 28.956 1.00 29.82 ? 196 ASN A C 1 ATOM 1324 O O . ASN A 1 160 ? 36.434 71.297 28.664 1.00 28.38 ? 196 ASN A O 1 ATOM 1325 C CB . ASN A 1 160 ? 33.803 72.153 29.696 1.00 29.35 ? 196 ASN A CB 1 ATOM 1326 C CG . ASN A 1 160 ? 32.706 72.509 30.689 1.00 31.09 ? 196 ASN A CG 1 ATOM 1327 O OD1 . ASN A 1 160 ? 31.686 71.826 30.787 1.00 32.54 ? 196 ASN A OD1 1 ATOM 1328 N ND2 . ASN A 1 160 ? 32.903 73.598 31.406 1.00 26.03 ? 196 ASN A ND2 1 ATOM 1329 N N . GLY A 1 161 ? 35.384 69.333 28.356 1.00 29.66 ? 197 GLY A N 1 ATOM 1330 C CA . GLY A 1 161 ? 36.208 68.983 27.214 1.00 25.23 ? 197 GLY A CA 1 ATOM 1331 C C . GLY A 1 161 ? 37.569 68.404 27.552 1.00 29.18 ? 197 GLY A C 1 ATOM 1332 O O . GLY A 1 161 ? 38.359 68.104 26.655 1.00 29.80 ? 197 GLY A O 1 ATOM 1333 N N . ILE A 1 162 ? 37.856 68.279 28.844 1.00 27.41 ? 198 ILE A N 1 ATOM 1334 C CA . ILE A 1 162 ? 39.024 67.535 29.322 1.00 26.93 ? 198 ILE A CA 1 ATOM 1335 C C . ILE A 1 162 ? 38.558 66.608 30.439 1.00 27.18 ? 198 ILE A C 1 ATOM 1336 O O . ILE A 1 162 ? 37.510 66.843 31.027 1.00 28.57 ? 198 ILE A O 1 ATOM 1337 C CB . ILE A 1 162 ? 40.126 68.458 29.857 1.00 24.06 ? 198 ILE A CB 1 ATOM 1338 C CG1 . ILE A 1 162 ? 39.527 69.474 30.837 1.00 26.49 ? 198 ILE A CG1 1 ATOM 1339 C CG2 . ILE A 1 162 ? 40.844 69.177 28.706 1.00 25.81 ? 198 ILE A CG2 1 ATOM 1340 C CD1 . ILE A 1 162 ? 40.524 70.471 31.355 1.00 31.14 ? 198 ILE A CD1 1 ATOM 1341 N N . THR A 1 163 ? 39.325 65.561 30.737 1.00 27.62 ? 199 THR A N 1 ATOM 1342 C CA . THR A 1 163 ? 38.960 64.629 31.802 1.00 26.15 ? 199 THR A CA 1 ATOM 1343 C C . THR A 1 163 ? 39.540 65.030 33.156 1.00 29.50 ? 199 THR A C 1 ATOM 1344 O O . THR A 1 163 ? 40.558 65.723 33.223 1.00 26.64 ? 199 THR A O 1 ATOM 1345 C CB . THR A 1 163 ? 39.503 63.236 31.520 1.00 26.70 ? 199 THR A CB 1 ATOM 1346 O OG1 . THR A 1 163 ? 40.894 63.354 31.197 1.00 28.40 ? 199 THR A OG1 1 ATOM 1347 C CG2 . THR A 1 163 ? 38.771 62.585 30.358 1.00 26.62 ? 199 THR A CG2 1 ATOM 1348 N N . ASP A 1 164 ? 38.903 64.567 34.232 1.00 26.91 ? 200 ASP A N 1 ATOM 1349 C CA . ASP A 1 164 ? 39.489 64.668 35.568 1.00 29.00 ? 200 ASP A CA 1 ATOM 1350 C C . ASP A 1 164 ? 40.469 63.517 35.789 1.00 29.45 ? 200 ASP A C 1 ATOM 1351 O O . ASP A 1 164 ? 40.648 62.683 34.898 1.00 27.11 ? 200 ASP A O 1 ATOM 1352 C CB . ASP A 1 164 ? 38.402 64.694 36.647 1.00 28.73 ? 200 ASP A CB 1 ATOM 1353 C CG . ASP A 1 164 ? 37.724 63.351 36.836 1.00 34.50 ? 200 ASP A CG 1 ATOM 1354 O OD1 . ASP A 1 164 ? 37.909 62.462 35.972 1.00 30.99 ? 200 ASP A OD1 1 ATOM 1355 O OD2 . ASP A 1 164 ? 36.999 63.185 37.853 1.00 30.99 ? 200 ASP A OD2 1 ATOM 1356 N N . TRP A 1 165 ? 41.098 63.450 36.963 1.00 25.04 ? 201 TRP A N 1 ATOM 1357 C CA . TRP A 1 165 ? 42.159 62.470 37.174 1.00 25.44 ? 201 TRP A CA 1 ATOM 1358 C C . TRP A 1 165 ? 41.746 61.051 36.767 1.00 26.18 ? 201 TRP A C 1 ATOM 1359 O O . TRP A 1 165 ? 42.446 60.386 36.010 1.00 24.28 ? 201 TRP A O 1 ATOM 1360 C CB . TRP A 1 165 ? 42.664 62.456 38.629 1.00 26.93 ? 201 TRP A CB 1 ATOM 1361 C CG . TRP A 1 165 ? 43.932 61.659 38.761 1.00 26.57 ? 201 TRP A CG 1 ATOM 1362 C CD1 . TRP A 1 165 ? 45.206 62.146 38.747 1.00 24.99 ? 201 TRP A CD1 1 ATOM 1363 C CD2 . TRP A 1 165 ? 44.048 60.230 38.879 1.00 22.69 ? 201 TRP A CD2 1 ATOM 1364 N NE1 . TRP A 1 165 ? 46.105 61.115 38.867 1.00 28.23 ? 201 TRP A NE1 1 ATOM 1365 C CE2 . TRP A 1 165 ? 45.421 59.928 38.937 1.00 23.75 ? 201 TRP A CE2 1 ATOM 1366 C CE3 . TRP A 1 165 ? 43.125 59.181 38.955 1.00 25.82 ? 201 TRP A CE3 1 ATOM 1367 C CZ2 . TRP A 1 165 ? 45.899 58.622 39.069 1.00 22.15 ? 201 TRP A CZ2 1 ATOM 1368 C CZ3 . TRP A 1 165 ? 43.600 57.876 39.079 1.00 24.52 ? 201 TRP A CZ3 1 ATOM 1369 C CH2 . TRP A 1 165 ? 44.974 57.610 39.124 1.00 22.01 ? 201 TRP A CH2 1 ATOM 1370 N N . VAL A 1 166 ? 40.620 60.580 37.287 1.00 24.95 ? 202 VAL A N 1 ATOM 1371 C CA . VAL A 1 166 ? 40.301 59.166 37.176 1.00 23.13 ? 202 VAL A CA 1 ATOM 1372 C C . VAL A 1 166 ? 39.797 58.798 35.783 1.00 24.06 ? 202 VAL A C 1 ATOM 1373 O O . VAL A 1 166 ? 40.048 57.690 35.309 1.00 24.33 ? 202 VAL A O 1 ATOM 1374 C CB . VAL A 1 166 ? 39.303 58.718 38.277 1.00 29.33 ? 202 VAL A CB 1 ATOM 1375 C CG1 . VAL A 1 166 ? 37.903 59.160 37.943 1.00 28.79 ? 202 VAL A CG1 1 ATOM 1376 C CG2 . VAL A 1 166 ? 39.353 57.219 38.468 1.00 22.67 ? 202 VAL A CG2 1 ATOM 1377 N N . TYR A 1 167 ? 39.109 59.728 35.122 1.00 24.35 ? 203 TYR A N 1 ATOM 1378 C CA . TYR A 1 167 ? 38.695 59.524 33.728 1.00 28.16 ? 203 TYR A CA 1 ATOM 1379 C C . TYR A 1 167 ? 39.913 59.550 32.798 1.00 28.61 ? 203 TYR A C 1 ATOM 1380 O O . TYR A 1 167 ? 40.022 58.736 31.884 1.00 26.89 ? 203 TYR A O 1 ATOM 1381 C CB . TYR A 1 167 ? 37.669 60.576 33.293 1.00 27.64 ? 203 TYR A CB 1 ATOM 1382 C CG . TYR A 1 167 ? 36.215 60.150 33.430 1.00 30.40 ? 203 TYR A CG 1 ATOM 1383 C CD1 . TYR A 1 167 ? 35.593 59.436 32.417 1.00 29.24 ? 203 TYR A CD1 1 ATOM 1384 C CD2 . TYR A 1 167 ? 35.465 60.469 34.559 1.00 29.83 ? 203 TYR A CD2 1 ATOM 1385 C CE1 . TYR A 1 167 ? 34.277 59.039 32.521 1.00 28.84 ? 203 TYR A CE1 1 ATOM 1386 C CE2 . TYR A 1 167 ? 34.132 60.078 34.667 1.00 28.78 ? 203 TYR A CE2 1 ATOM 1387 C CZ . TYR A 1 167 ? 33.547 59.368 33.628 1.00 30.55 ? 203 TYR A CZ 1 ATOM 1388 O OH . TYR A 1 167 ? 32.241 58.952 33.682 1.00 28.84 ? 203 TYR A OH 1 ATOM 1389 N N . GLU A 1 168 ? 40.843 60.469 33.044 1.00 24.71 ? 204 GLU A N 1 ATOM 1390 C CA . GLU A 1 168 ? 42.086 60.483 32.280 1.00 26.07 ? 204 GLU A CA 1 ATOM 1391 C C . GLU A 1 168 ? 42.827 59.150 32.400 1.00 27.62 ? 204 GLU A C 1 ATOM 1392 O O . GLU A 1 168 ? 43.271 58.593 31.409 1.00 24.93 ? 204 GLU A O 1 ATOM 1393 C CB . GLU A 1 168 ? 43.018 61.604 32.749 1.00 26.11 ? 204 GLU A CB 1 ATOM 1394 C CG . GLU A 1 168 ? 44.453 61.421 32.227 1.00 24.24 ? 204 GLU A CG 1 ATOM 1395 C CD . GLU A 1 168 ? 45.399 62.529 32.609 1.00 28.53 ? 204 GLU A CD 1 ATOM 1396 O OE1 . GLU A 1 168 ? 44.956 63.554 33.175 1.00 29.96 ? 204 GLU A OE1 1 ATOM 1397 O OE2 . GLU A 1 168 ? 46.607 62.371 32.344 1.00 29.96 ? 204 GLU A OE2 1 ATOM 1398 N N . GLU A 1 169 ? 42.957 58.638 33.623 1.00 27.21 ? 205 GLU A N 1 ATOM 1399 C CA . GLU A 1 169 ? 43.791 57.457 33.864 1.00 25.40 ? 205 GLU A CA 1 ATOM 1400 C C . GLU A 1 169 ? 43.137 56.130 33.502 1.00 29.04 ? 205 GLU A C 1 ATOM 1401 O O . GLU A 1 169 ? 43.798 55.248 32.955 1.00 28.42 ? 205 GLU A O 1 ATOM 1402 C CB . GLU A 1 169 ? 44.235 57.397 35.331 1.00 26.36 ? 205 GLU A CB 1 ATOM 1403 C CG . GLU A 1 169 ? 44.949 56.106 35.750 1.00 24.82 ? 205 GLU A CG 1 ATOM 1404 C CD . GLU A 1 169 ? 46.416 56.031 35.295 1.00 27.77 ? 205 GLU A CD 1 ATOM 1405 O OE1 . GLU A 1 169 ? 46.898 56.961 34.599 1.00 26.80 ? 205 GLU A OE1 1 ATOM 1406 O OE2 . GLU A 1 169 ? 47.087 55.026 35.644 1.00 26.03 ? 205 GLU A OE2 1 ATOM 1407 N N . GLU A 1 170 ? 41.858 55.979 33.846 1.00 23.76 ? 206 GLU A N 1 ATOM 1408 C CA . GLU A 1 170 ? 41.220 54.666 33.892 1.00 25.25 ? 206 GLU A CA 1 ATOM 1409 C C . GLU A 1 170 ? 40.126 54.476 32.844 1.00 28.24 ? 206 GLU A C 1 ATOM 1410 O O . GLU A 1 170 ? 39.717 53.352 32.581 1.00 31.19 ? 206 GLU A O 1 ATOM 1411 C CB . GLU A 1 170 ? 40.605 54.429 35.274 1.00 25.02 ? 206 GLU A CB 1 ATOM 1412 C CG . GLU A 1 170 ? 41.568 54.588 36.441 1.00 25.47 ? 206 GLU A CG 1 ATOM 1413 C CD . GLU A 1 170 ? 42.616 53.486 36.504 1.00 29.35 ? 206 GLU A CD 1 ATOM 1414 O OE1 . GLU A 1 170 ? 42.767 52.723 35.521 1.00 28.90 ? 206 GLU A OE1 1 ATOM 1415 O OE2 . GLU A 1 170 ? 43.300 53.387 37.544 1.00 27.45 ? 206 GLU A OE2 1 ATOM 1416 N N . VAL A 1 171 ? 39.635 55.568 32.268 1.00 28.82 ? 207 VAL A N 1 ATOM 1417 C CA . VAL A 1 171 ? 38.484 55.491 31.373 1.00 27.26 ? 207 VAL A CA 1 ATOM 1418 C C . VAL A 1 171 ? 38.853 55.818 29.920 1.00 31.85 ? 207 VAL A C 1 ATOM 1419 O O . VAL A 1 171 ? 38.786 54.942 29.072 1.00 28.65 ? 207 VAL A O 1 ATOM 1420 C CB . VAL A 1 171 ? 37.304 56.343 31.889 1.00 29.48 ? 207 VAL A CB 1 ATOM 1421 C CG1 . VAL A 1 171 ? 36.108 56.227 30.960 1.00 31.05 ? 207 VAL A CG1 1 ATOM 1422 C CG2 . VAL A 1 171 ? 36.915 55.912 33.302 1.00 25.63 ? 207 VAL A CG2 1 ATOM 1423 N N . PHE A 1 172 ? 39.295 57.043 29.634 1.00 26.65 ? 208 PHE A N 1 ATOM 1424 C CA . PHE A 1 172 ? 39.611 57.418 28.253 1.00 28.56 ? 208 PHE A CA 1 ATOM 1425 C C . PHE A 1 172 ? 41.076 57.270 27.863 1.00 27.04 ? 208 PHE A C 1 ATOM 1426 O O . PHE A 1 172 ? 41.413 57.400 26.692 1.00 28.76 ? 208 PHE A O 1 ATOM 1427 C CB . PHE A 1 172 ? 39.219 58.871 27.984 1.00 26.47 ? 208 PHE A CB 1 ATOM 1428 C CG . PHE A 1 172 ? 37.751 59.149 28.115 1.00 27.68 ? 208 PHE A CG 1 ATOM 1429 C CD1 . PHE A 1 172 ? 36.831 58.133 28.099 1.00 37.98 ? 208 PHE A CD1 1 ATOM 1430 C CD2 . PHE A 1 172 ? 37.294 60.440 28.230 1.00 34.15 ? 208 PHE A CD2 1 ATOM 1431 C CE1 . PHE A 1 172 ? 35.473 58.403 28.207 1.00 39.41 ? 208 PHE A CE1 1 ATOM 1432 C CE2 . PHE A 1 172 ? 35.939 60.708 28.341 1.00 38.56 ? 208 PHE A CE2 1 ATOM 1433 C CZ . PHE A 1 172 ? 35.034 59.682 28.333 1.00 31.09 ? 208 PHE A CZ 1 ATOM 1434 N N . SER A 1 173 ? 41.954 57.057 28.835 1.00 27.95 ? 209 SER A N 1 ATOM 1435 C CA . SER A 1 173 ? 43.389 57.017 28.563 1.00 28.59 ? 209 SER A CA 1 ATOM 1436 C C . SER A 1 173 ? 43.833 58.246 27.788 1.00 28.16 ? 209 SER A C 1 ATOM 1437 O O . SER A 1 173 ? 44.641 58.146 26.873 1.00 28.24 ? 209 SER A O 1 ATOM 1438 C CB . SER A 1 173 ? 43.747 55.757 27.760 1.00 29.82 ? 209 SER A CB 1 ATOM 1439 O OG . SER A 1 173 ? 43.365 54.577 28.468 1.00 29.88 ? 209 SER A OG 1 ATOM 1440 N N . ALA A 1 174 ? 43.295 59.402 28.145 1.00 21.61 ? 210 ALA A N 1 ATOM 1441 C CA . ALA A 1 174 ? 43.616 60.637 27.448 1.00 24.41 ? 210 ALA A CA 1 ATOM 1442 C C . ALA A 1 174 ? 43.130 61.817 28.280 1.00 25.11 ? 210 ALA A C 1 ATOM 1443 O O . ALA A 1 174 ? 42.274 61.662 29.158 1.00 25.21 ? 210 ALA A O 1 ATOM 1444 C CB . ALA A 1 174 ? 42.960 60.658 26.040 1.00 27.17 ? 210 ALA A CB 1 ATOM 1445 N N . TYR A 1 175 ? 43.681 62.995 28.014 1.00 22.11 ? 211 TYR A N 1 ATOM 1446 C CA . TYR A 1 175 ? 43.242 64.217 28.697 1.00 26.35 ? 211 TYR A CA 1 ATOM 1447 C C . TYR A 1 175 ? 42.034 64.755 27.957 1.00 28.09 ? 211 TYR A C 1 ATOM 1448 O O . TYR A 1 175 ? 41.169 65.400 28.541 1.00 29.00 ? 211 TYR A O 1 ATOM 1449 C CB . TYR A 1 175 ? 44.334 65.287 28.635 1.00 23.73 ? 211 TYR A CB 1 ATOM 1450 C CG . TYR A 1 175 ? 44.156 66.452 29.616 1.00 27.12 ? 211 TYR A CG 1 ATOM 1451 C CD1 . TYR A 1 175 ? 43.382 66.333 30.774 1.00 25.40 ? 211 TYR A CD1 1 ATOM 1452 C CD2 . TYR A 1 175 ? 44.793 67.658 29.384 1.00 29.23 ? 211 TYR A CD2 1 ATOM 1453 C CE1 . TYR A 1 175 ? 43.255 67.427 31.685 1.00 28.28 ? 211 TYR A CE1 1 ATOM 1454 C CE2 . TYR A 1 175 ? 44.683 68.722 30.263 1.00 28.87 ? 211 TYR A CE2 1 ATOM 1455 C CZ . TYR A 1 175 ? 43.919 68.611 31.397 1.00 25.66 ? 211 TYR A CZ 1 ATOM 1456 O OH . TYR A 1 175 ? 43.839 69.716 32.203 1.00 33.22 ? 211 TYR A OH 1 ATOM 1457 N N . SER A 1 176 ? 41.997 64.508 26.650 1.00 22.75 ? 212 SER A N 1 ATOM 1458 C CA . SER A 1 176 ? 40.941 65.032 25.797 1.00 23.94 ? 212 SER A CA 1 ATOM 1459 C C . SER A 1 176 ? 39.573 64.429 26.125 1.00 27.98 ? 212 SER A C 1 ATOM 1460 O O . SER A 1 176 ? 39.449 63.222 26.353 1.00 26.00 ? 212 SER A O 1 ATOM 1461 C CB . SER A 1 176 ? 41.286 64.743 24.328 1.00 32.28 ? 212 SER A CB 1 ATOM 1462 O OG . SER A 1 176 ? 40.195 65.033 23.473 1.00 33.13 ? 212 SER A OG 1 ATOM 1463 N N . ALA A 1 177 ? 38.546 65.273 26.131 1.00 26.52 ? 213 ALA A N 1 ATOM 1464 C CA . ALA A 1 177 ? 37.169 64.793 26.124 1.00 31.00 ? 213 ALA A CA 1 ATOM 1465 C C . ALA A 1 177 ? 36.363 65.587 25.099 1.00 30.40 ? 213 ALA A C 1 ATOM 1466 O O . ALA A 1 177 ? 35.248 66.025 25.374 1.00 31.25 ? 213 ALA A O 1 ATOM 1467 C CB . ALA A 1 177 ? 36.536 64.898 27.507 1.00 28.56 ? 213 ALA A CB 1 ATOM 1468 N N . LEU A 1 178 ? 36.964 65.791 23.930 1.00 33.84 ? 214 LEU A N 1 ATOM 1469 C CA . LEU A 1 178 ? 36.320 66.438 22.784 1.00 29.91 ? 214 LEU A CA 1 ATOM 1470 C C . LEU A 1 178 ? 36.315 65.447 21.617 1.00 31.77 ? 214 LEU A C 1 ATOM 1471 O O . LEU A 1 178 ? 37.304 64.729 21.408 1.00 30.19 ? 214 LEU A O 1 ATOM 1472 C CB . LEU A 1 178 ? 37.111 67.686 22.359 1.00 32.64 ? 214 LEU A CB 1 ATOM 1473 C CG . LEU A 1 178 ? 37.260 68.863 23.323 1.00 33.07 ? 214 LEU A CG 1 ATOM 1474 C CD1 . LEU A 1 178 ? 37.919 70.039 22.627 1.00 32.66 ? 214 LEU A CD1 1 ATOM 1475 C CD2 . LEU A 1 178 ? 35.893 69.252 23.836 1.00 35.38 ? 214 LEU A CD2 1 ATOM 1476 N N . TRP A 1 179 ? 35.233 65.423 20.839 1.00 30.79 ? 215 TRP A N 1 ATOM 1477 C CA . TRP A 1 179 ? 35.168 64.567 19.651 1.00 29.53 ? 215 TRP A CA 1 ATOM 1478 C C . TRP A 1 179 ? 34.497 65.288 18.484 1.00 29.94 ? 215 TRP A C 1 ATOM 1479 O O . TRP A 1 179 ? 33.285 65.490 18.494 1.00 29.28 ? 215 TRP A O 1 ATOM 1480 C CB . TRP A 1 179 ? 34.389 63.295 19.954 1.00 26.32 ? 215 TRP A CB 1 ATOM 1481 C CG . TRP A 1 179 ? 34.972 62.460 21.065 1.00 30.33 ? 215 TRP A CG 1 ATOM 1482 C CD1 . TRP A 1 179 ? 35.869 61.443 20.935 1.00 31.21 ? 215 TRP A CD1 1 ATOM 1483 C CD2 . TRP A 1 179 ? 34.677 62.558 22.470 1.00 31.58 ? 215 TRP A CD2 1 ATOM 1484 N NE1 . TRP A 1 179 ? 36.157 60.904 22.169 1.00 28.83 ? 215 TRP A NE1 1 ATOM 1485 C CE2 . TRP A 1 179 ? 35.438 61.572 23.127 1.00 31.26 ? 215 TRP A CE2 1 ATOM 1486 C CE3 . TRP A 1 179 ? 33.840 63.382 23.233 1.00 32.70 ? 215 TRP A CE3 1 ATOM 1487 C CZ2 . TRP A 1 179 ? 35.399 61.392 24.517 1.00 32.69 ? 215 TRP A CZ2 1 ATOM 1488 C CZ3 . TRP A 1 179 ? 33.805 63.201 24.621 1.00 32.25 ? 215 TRP A CZ3 1 ATOM 1489 C CH2 . TRP A 1 179 ? 34.573 62.213 25.241 1.00 32.45 ? 215 TRP A CH2 1 ATOM 1490 N N . TRP A 1 180 ? 35.285 65.677 17.486 1.00 30.80 ? 216 TRP A N 1 ATOM 1491 C CA . TRP A 1 180 ? 34.751 66.295 16.268 1.00 33.96 ? 216 TRP A CA 1 ATOM 1492 C C . TRP A 1 180 ? 33.983 65.259 15.464 1.00 33.36 ? 216 TRP A C 1 ATOM 1493 O O . TRP A 1 180 ? 34.398 64.103 15.404 1.00 33.84 ? 216 TRP A O 1 ATOM 1494 C CB . TRP A 1 180 ? 35.896 66.796 15.391 1.00 33.46 ? 216 TRP A CB 1 ATOM 1495 C CG . TRP A 1 180 ? 36.513 68.072 15.817 1.00 31.66 ? 216 TRP A CG 1 ATOM 1496 C CD1 . TRP A 1 180 ? 37.695 68.230 16.478 1.00 33.97 ? 216 TRP A CD1 1 ATOM 1497 C CD2 . TRP A 1 180 ? 35.992 69.389 15.604 1.00 32.60 ? 216 TRP A CD2 1 ATOM 1498 N NE1 . TRP A 1 180 ? 37.944 69.563 16.685 1.00 31.35 ? 216 TRP A NE1 1 ATOM 1499 C CE2 . TRP A 1 180 ? 36.913 70.297 16.162 1.00 32.61 ? 216 TRP A CE2 1 ATOM 1500 C CE3 . TRP A 1 180 ? 34.840 69.890 14.985 1.00 34.91 ? 216 TRP A CE3 1 ATOM 1501 C CZ2 . TRP A 1 180 ? 36.721 71.684 16.121 1.00 35.41 ? 216 TRP A CZ2 1 ATOM 1502 C CZ3 . TRP A 1 180 ? 34.647 71.267 14.946 1.00 36.73 ? 216 TRP A CZ3 1 ATOM 1503 C CH2 . TRP A 1 180 ? 35.585 72.147 15.515 1.00 36.17 ? 216 TRP A CH2 1 ATOM 1504 N N . SER A 1 181 ? 32.882 65.665 14.834 1.00 35.14 ? 217 SER A N 1 ATOM 1505 C CA . SER A 1 181 ? 32.209 64.808 13.850 1.00 34.55 ? 217 SER A CA 1 ATOM 1506 C C . SER A 1 181 ? 33.100 64.717 12.614 1.00 36.64 ? 217 SER A C 1 ATOM 1507 O O . SER A 1 181 ? 33.932 65.592 12.399 1.00 35.51 ? 217 SER A O 1 ATOM 1508 C CB . SER A 1 181 ? 30.844 65.385 13.464 1.00 34.88 ? 217 SER A CB 1 ATOM 1509 O OG . SER A 1 181 ? 30.986 66.582 12.715 1.00 34.35 ? 217 SER A OG 1 ATOM 1510 N N . PRO A 1 182 ? 32.940 63.654 11.802 1.00 36.13 ? 218 PRO A N 1 ATOM 1511 C CA . PRO A 1 182 ? 33.842 63.448 10.661 1.00 38.31 ? 218 PRO A CA 1 ATOM 1512 C C . PRO A 1 182 ? 33.937 64.685 9.762 1.00 38.28 ? 218 PRO A C 1 ATOM 1513 O O . PRO A 1 182 ? 35.014 65.007 9.265 1.00 39.66 ? 218 PRO A O 1 ATOM 1514 C CB . PRO A 1 182 ? 33.181 62.291 9.904 1.00 41.64 ? 218 PRO A CB 1 ATOM 1515 C CG . PRO A 1 182 ? 32.470 61.521 10.960 1.00 38.42 ? 218 PRO A CG 1 ATOM 1516 C CD . PRO A 1 182 ? 31.977 62.549 11.952 1.00 36.06 ? 218 PRO A CD 1 ATOM 1517 N N . ASN A 1 183 ? 32.806 65.362 9.592 1.00 40.16 ? 219 ASN A N 1 ATOM 1518 C CA . ASN A 1 183 ? 32.663 66.583 8.794 1.00 44.80 ? 219 ASN A CA 1 ATOM 1519 C C . ASN A 1 183 ? 33.335 67.827 9.372 1.00 43.99 ? 219 ASN A C 1 ATOM 1520 O O . ASN A 1 183 ? 33.573 68.805 8.655 1.00 43.14 ? 219 ASN A O 1 ATOM 1521 C CB . ASN A 1 183 ? 31.174 66.915 8.716 1.00 46.41 ? 219 ASN A CB 1 ATOM 1522 C CG . ASN A 1 183 ? 30.737 67.235 7.337 1.00 53.44 ? 219 ASN A CG 1 ATOM 1523 O OD1 . ASN A 1 183 ? 31.532 67.718 6.532 1.00 65.12 ? 219 ASN A OD1 1 ATOM 1524 N ND2 . ASN A 1 183 ? 29.470 66.944 7.023 1.00 56.12 ? 219 ASN A ND2 1 ATOM 1525 N N . GLY A 1 184 ? 33.593 67.805 10.679 1.00 40.85 ? 220 GLY A N 1 ATOM 1526 C CA . GLY A 1 184 ? 33.986 69.002 11.405 1.00 38.14 ? 220 GLY A CA 1 ATOM 1527 C C . GLY A 1 184 ? 32.802 69.909 11.719 1.00 38.75 ? 220 GLY A C 1 ATOM 1528 O O . GLY A 1 184 ? 32.974 71.040 12.170 1.00 40.06 ? 220 GLY A O 1 ATOM 1529 N N . THR A 1 185 ? 31.592 69.421 11.473 1.00 34.12 ? 221 THR A N 1 ATOM 1530 C CA . THR A 1 185 ? 30.400 70.225 11.694 1.00 37.42 ? 221 THR A CA 1 ATOM 1531 C C . THR A 1 185 ? 30.049 70.322 13.172 1.00 40.15 ? 221 THR A C 1 ATOM 1532 O O . THR A 1 185 ? 29.827 71.414 13.696 1.00 40.13 ? 221 THR A O 1 ATOM 1533 C CB . THR A 1 185 ? 29.202 69.657 10.922 1.00 42.58 ? 221 THR A CB 1 ATOM 1534 O OG1 . THR A 1 185 ? 29.453 69.767 9.515 1.00 49.94 ? 221 THR A OG1 1 ATOM 1535 C CG2 . THR A 1 185 ? 27.927 70.413 11.270 1.00 44.48 ? 221 THR A CG2 1 ATOM 1536 N N . PHE A 1 186 ? 29.993 69.169 13.837 1.00 39.24 ? 222 PHE A N 1 ATOM 1537 C CA . PHE A 1 186 ? 29.674 69.106 15.256 1.00 34.22 ? 222 PHE A CA 1 ATOM 1538 C C . PHE A 1 186 ? 30.927 68.909 16.097 1.00 33.02 ? 222 PHE A C 1 ATOM 1539 O O . PHE A 1 186 ? 31.890 68.270 15.664 1.00 32.01 ? 222 PHE A O 1 ATOM 1540 C CB . PHE A 1 186 ? 28.728 67.947 15.535 1.00 34.11 ? 222 PHE A CB 1 ATOM 1541 C CG . PHE A 1 186 ? 27.435 68.027 14.788 1.00 40.15 ? 222 PHE A CG 1 ATOM 1542 C CD1 . PHE A 1 186 ? 26.440 68.910 15.188 1.00 40.77 ? 222 PHE A CD1 1 ATOM 1543 C CD2 . PHE A 1 186 ? 27.199 67.202 13.696 1.00 40.28 ? 222 PHE A CD2 1 ATOM 1544 C CE1 . PHE A 1 186 ? 25.233 68.981 14.499 1.00 43.56 ? 222 PHE A CE1 1 ATOM 1545 C CE2 . PHE A 1 186 ? 25.993 67.263 13.000 1.00 40.31 ? 222 PHE A CE2 1 ATOM 1546 C CZ . PHE A 1 186 ? 25.010 68.150 13.404 1.00 42.68 ? 222 PHE A CZ 1 ATOM 1547 N N . LEU A 1 187 ? 30.892 69.456 17.306 1.00 35.81 ? 223 LEU A N 1 ATOM 1548 C CA . LEU A 1 187 ? 31.870 69.145 18.341 1.00 31.07 ? 223 LEU A CA 1 ATOM 1549 C C . LEU A 1 187 ? 31.116 68.574 19.522 1.00 32.41 ? 223 LEU A C 1 ATOM 1550 O O . LEU A 1 187 ? 30.301 69.263 20.140 1.00 32.10 ? 223 LEU A O 1 ATOM 1551 C CB . LEU A 1 187 ? 32.642 70.403 18.754 1.00 32.48 ? 223 LEU A CB 1 ATOM 1552 C CG . LEU A 1 187 ? 33.745 70.257 19.808 1.00 31.25 ? 223 LEU A CG 1 ATOM 1553 C CD1 . LEU A 1 187 ? 34.853 69.323 19.326 1.00 29.38 ? 223 LEU A CD1 1 ATOM 1554 C CD2 . LEU A 1 187 ? 34.329 71.614 20.187 1.00 31.77 ? 223 LEU A CD2 1 ATOM 1555 N N . ALA A 1 188 ? 31.349 67.301 19.826 1.00 28.27 ? 224 ALA A N 1 ATOM 1556 C CA . ALA A 1 188 ? 30.746 66.705 21.005 1.00 29.24 ? 224 ALA A CA 1 ATOM 1557 C C . ALA A 1 188 ? 31.748 66.777 22.153 1.00 31.14 ? 224 ALA A C 1 ATOM 1558 O O . ALA A 1 188 ? 32.948 66.803 21.918 1.00 30.77 ? 224 ALA A O 1 ATOM 1559 C CB . ALA A 1 188 ? 30.359 65.275 20.741 1.00 30.78 ? 224 ALA A CB 1 ATOM 1560 N N . TYR A 1 189 ? 31.266 66.808 23.391 1.00 30.76 ? 225 TYR A N 1 ATOM 1561 C CA . TYR A 1 189 ? 32.169 66.941 24.531 1.00 29.35 ? 225 TYR A CA 1 ATOM 1562 C C . TYR A 1 189 ? 31.529 66.478 25.834 1.00 30.33 ? 225 TYR A C 1 ATOM 1563 O O . TYR A 1 189 ? 30.314 66.559 25.992 1.00 30.75 ? 225 TYR A O 1 ATOM 1564 C CB . TYR A 1 189 ? 32.674 68.380 24.649 1.00 31.19 ? 225 TYR A CB 1 ATOM 1565 C CG . TYR A 1 189 ? 31.622 69.399 25.055 1.00 33.98 ? 225 TYR A CG 1 ATOM 1566 C CD1 . TYR A 1 189 ? 31.372 69.680 26.396 1.00 31.32 ? 225 TYR A CD1 1 ATOM 1567 C CD2 . TYR A 1 189 ? 30.895 70.095 24.095 1.00 34.20 ? 225 TYR A CD2 1 ATOM 1568 C CE1 . TYR A 1 189 ? 30.416 70.628 26.771 1.00 32.97 ? 225 TYR A CE1 1 ATOM 1569 C CE2 . TYR A 1 189 ? 29.941 71.033 24.455 1.00 34.84 ? 225 TYR A CE2 1 ATOM 1570 C CZ . TYR A 1 189 ? 29.700 71.292 25.789 1.00 36.16 ? 225 TYR A CZ 1 ATOM 1571 O OH . TYR A 1 189 ? 28.752 72.227 26.118 1.00 33.72 ? 225 TYR A OH 1 ATOM 1572 N N . ALA A 1 190 ? 32.348 65.956 26.746 1.00 26.49 ? 226 ALA A N 1 ATOM 1573 C CA . ALA A 1 190 ? 31.858 65.528 28.048 1.00 30.81 ? 226 ALA A CA 1 ATOM 1574 C C . ALA A 1 190 ? 32.137 66.623 29.051 1.00 29.70 ? 226 ALA A C 1 ATOM 1575 O O . ALA A 1 190 ? 33.036 67.456 28.857 1.00 28.98 ? 226 ALA A O 1 ATOM 1576 C CB . ALA A 1 190 ? 32.540 64.235 28.493 1.00 30.15 ? 226 ALA A CB 1 ATOM 1577 N N . GLN A 1 191 ? 31.371 66.623 30.128 1.00 29.47 ? 227 GLN A N 1 ATOM 1578 C CA . GLN A 1 191 ? 31.613 67.547 31.227 1.00 31.58 ? 227 GLN A CA 1 ATOM 1579 C C . GLN A 1 191 ? 31.643 66.753 32.520 1.00 29.72 ? 227 GLN A C 1 ATOM 1580 O O . GLN A 1 191 ? 30.714 66.013 32.817 1.00 28.38 ? 227 GLN A O 1 ATOM 1581 C CB . GLN A 1 191 ? 30.511 68.601 31.293 1.00 32.35 ? 227 GLN A CB 1 ATOM 1582 C CG . GLN A 1 191 ? 30.661 69.576 32.443 1.00 30.62 ? 227 GLN A CG 1 ATOM 1583 C CD . GLN A 1 191 ? 29.370 70.298 32.718 1.00 35.02 ? 227 GLN A CD 1 ATOM 1584 O OE1 . GLN A 1 191 ? 28.457 69.734 33.311 1.00 32.50 ? 227 GLN A OE1 1 ATOM 1585 N NE2 . GLN A 1 191 ? 29.270 71.542 32.252 1.00 32.53 ? 227 GLN A NE2 1 ATOM 1586 N N . PHE A 1 192 ? 32.718 66.892 33.285 1.00 26.38 ? 228 PHE A N 1 ATOM 1587 C CA . PHE A 1 192 ? 32.850 66.125 34.508 1.00 26.30 ? 228 PHE A CA 1 ATOM 1588 C C . PHE A 1 192 ? 32.669 67.044 35.703 1.00 28.22 ? 228 PHE A C 1 ATOM 1589 O O . PHE A 1 192 ? 33.145 68.177 35.707 1.00 28.85 ? 228 PHE A O 1 ATOM 1590 C CB . PHE A 1 192 ? 34.204 65.425 34.548 1.00 26.94 ? 228 PHE A CB 1 ATOM 1591 C CG . PHE A 1 192 ? 34.466 64.576 33.341 1.00 26.52 ? 228 PHE A CG 1 ATOM 1592 C CD1 . PHE A 1 192 ? 34.025 63.264 33.295 1.00 28.37 ? 228 PHE A CD1 1 ATOM 1593 C CD2 . PHE A 1 192 ? 35.112 65.098 32.238 1.00 28.78 ? 228 PHE A CD2 1 ATOM 1594 C CE1 . PHE A 1 192 ? 34.243 62.488 32.173 1.00 29.81 ? 228 PHE A CE1 1 ATOM 1595 C CE2 . PHE A 1 192 ? 35.334 64.324 31.113 1.00 25.32 ? 228 PHE A CE2 1 ATOM 1596 C CZ . PHE A 1 192 ? 34.896 63.028 31.084 1.00 26.19 ? 228 PHE A CZ 1 ATOM 1597 N N . ASN A 1 193 ? 31.964 66.550 36.709 1.00 30.33 ? 229 ASN A N 1 ATOM 1598 C CA . ASN A 1 193 ? 31.678 67.333 37.905 1.00 29.25 ? 229 ASN A CA 1 ATOM 1599 C C . ASN A 1 193 ? 32.305 66.607 39.074 1.00 26.60 ? 229 ASN A C 1 ATOM 1600 O O . ASN A 1 193 ? 31.876 65.512 39.421 1.00 28.40 ? 229 ASN A O 1 ATOM 1601 C CB . ASN A 1 193 ? 30.163 67.461 38.099 1.00 30.30 ? 229 ASN A CB 1 ATOM 1602 C CG . ASN A 1 193 ? 29.784 68.561 39.085 1.00 36.17 ? 229 ASN A CG 1 ATOM 1603 O OD1 . ASN A 1 193 ? 30.564 68.903 39.976 1.00 35.25 ? 229 ASN A OD1 1 ATOM 1604 N ND2 . ASN A 1 193 ? 28.574 69.108 38.934 1.00 37.52 ? 229 ASN A ND2 1 ATOM 1605 N N . ASP A 1 194 ? 33.346 67.198 39.657 1.00 26.80 ? 230 ASP A N 1 ATOM 1606 C CA . ASP A 1 194 ? 34.059 66.571 40.776 1.00 28.16 ? 230 ASP A CA 1 ATOM 1607 C C . ASP A 1 194 ? 33.741 67.220 42.128 1.00 32.41 ? 230 ASP A C 1 ATOM 1608 O O . ASP A 1 194 ? 34.470 67.023 43.106 1.00 28.82 ? 230 ASP A O 1 ATOM 1609 C CB . ASP A 1 194 ? 35.568 66.648 40.545 1.00 28.96 ? 230 ASP A CB 1 ATOM 1610 C CG . ASP A 1 194 ? 36.056 65.626 39.530 1.00 34.94 ? 230 ASP A CG 1 ATOM 1611 O OD1 . ASP A 1 194 ? 35.419 65.497 38.461 1.00 33.86 ? 230 ASP A OD1 1 ATOM 1612 O OD2 . ASP A 1 194 ? 37.062 64.943 39.808 1.00 33.69 ? 230 ASP A OD2 1 ATOM 1613 N N . THR A 1 195 ? 32.668 67.999 42.183 1.00 30.72 ? 231 THR A N 1 ATOM 1614 C CA . THR A 1 195 ? 32.352 68.761 43.399 1.00 32.87 ? 231 THR A CA 1 ATOM 1615 C C . THR A 1 195 ? 32.501 67.975 44.703 1.00 36.33 ? 231 THR A C 1 ATOM 1616 O O . THR A 1 195 ? 33.097 68.468 45.674 1.00 38.64 ? 231 THR A O 1 ATOM 1617 C CB . THR A 1 195 ? 30.952 69.369 43.344 1.00 33.69 ? 231 THR A CB 1 ATOM 1618 O OG1 . THR A 1 195 ? 30.940 70.422 42.372 1.00 35.08 ? 231 THR A OG1 1 ATOM 1619 C CG2 . THR A 1 195 ? 30.571 69.953 44.724 1.00 38.68 ? 231 THR A CG2 1 ATOM 1620 N N . GLU A 1 196 ? 31.968 66.761 44.743 1.00 32.72 ? 232 GLU A N 1 ATOM 1621 C CA . GLU A 1 196 ? 32.012 66.009 46.002 1.00 36.72 ? 232 GLU A CA 1 ATOM 1622 C C . GLU A 1 196 ? 33.045 64.881 46.056 1.00 32.96 ? 232 GLU A C 1 ATOM 1623 O O . GLU A 1 196 ? 32.995 64.036 46.938 1.00 31.14 ? 232 GLU A O 1 ATOM 1624 C CB . GLU A 1 196 ? 30.617 65.480 46.363 1.00 40.60 ? 232 GLU A CB 1 ATOM 1625 C CG . GLU A 1 196 ? 29.609 66.588 46.693 1.00 45.35 ? 232 GLU A CG 1 ATOM 1626 C CD . GLU A 1 196 ? 28.186 66.064 46.860 1.00 62.15 ? 232 GLU A CD 1 ATOM 1627 O OE1 . GLU A 1 196 ? 27.600 66.251 47.954 1.00 62.99 ? 232 GLU A OE1 1 ATOM 1628 O OE2 . GLU A 1 196 ? 27.654 65.467 45.896 1.00 57.15 ? 232 GLU A OE2 1 ATOM 1629 N N . VAL A 1 197 ? 33.978 64.857 45.113 1.00 29.14 ? 233 VAL A N 1 ATOM 1630 C CA . VAL A 1 197 ? 35.023 63.843 45.138 1.00 29.90 ? 233 VAL A CA 1 ATOM 1631 C C . VAL A 1 197 ? 36.058 64.247 46.212 1.00 25.15 ? 233 VAL A C 1 ATOM 1632 O O . VAL A 1 197 ? 36.426 65.408 46.294 1.00 28.10 ? 233 VAL A O 1 ATOM 1633 C CB . VAL A 1 197 ? 35.675 63.700 43.737 1.00 29.35 ? 233 VAL A CB 1 ATOM 1634 C CG1 . VAL A 1 197 ? 36.726 62.609 43.748 1.00 26.12 ? 233 VAL A CG1 1 ATOM 1635 C CG2 . VAL A 1 197 ? 34.600 63.395 42.678 1.00 29.49 ? 233 VAL A CG2 1 ATOM 1636 N N . PRO A 1 198 ? 36.494 63.305 47.061 1.00 24.96 ? 234 PRO A N 1 ATOM 1637 C CA . PRO A 1 198 ? 37.489 63.681 48.076 1.00 25.28 ? 234 PRO A CA 1 ATOM 1638 C C . PRO A 1 198 ? 38.858 63.958 47.456 1.00 31.68 ? 234 PRO A C 1 ATOM 1639 O O . PRO A 1 198 ? 39.136 63.546 46.319 1.00 26.43 ? 234 PRO A O 1 ATOM 1640 C CB . PRO A 1 198 ? 37.564 62.443 48.982 1.00 28.12 ? 234 PRO A CB 1 ATOM 1641 C CG . PRO A 1 198 ? 36.317 61.654 48.694 1.00 29.27 ? 234 PRO A CG 1 ATOM 1642 C CD . PRO A 1 198 ? 36.036 61.918 47.228 1.00 26.90 ? 234 PRO A CD 1 ATOM 1643 N N . LEU A 1 199 ? 39.718 64.641 48.200 1.00 27.45 ? 235 LEU A N 1 ATOM 1644 C CA . LEU A 1 199 ? 41.034 65.002 47.693 1.00 29.07 ? 235 LEU A CA 1 ATOM 1645 C C . LEU A 1 199 ? 42.112 64.131 48.319 1.00 31.25 ? 235 LEU A C 1 ATOM 1646 O O . LEU A 1 199 ? 42.078 63.858 49.521 1.00 30.69 ? 235 LEU A O 1 ATOM 1647 C CB . LEU A 1 199 ? 41.326 66.466 48.003 1.00 34.37 ? 235 LEU A CB 1 ATOM 1648 C CG . LEU A 1 199 ? 40.247 67.462 47.579 1.00 35.93 ? 235 LEU A CG 1 ATOM 1649 C CD1 . LEU A 1 199 ? 40.462 68.800 48.255 1.00 37.88 ? 235 LEU A CD1 1 ATOM 1650 C CD2 . LEU A 1 199 ? 40.239 67.628 46.069 1.00 33.37 ? 235 LEU A CD2 1 ATOM 1651 N N . ILE A 1 200 ? 43.047 63.656 47.498 1.00 29.23 ? 236 ILE A N 1 ATOM 1652 C CA . ILE A 1 200 ? 44.265 63.071 48.030 1.00 28.27 ? 236 ILE A CA 1 ATOM 1653 C C . ILE A 1 200 ? 45.189 64.257 48.186 1.00 30.78 ? 236 ILE A C 1 ATOM 1654 O O . ILE A 1 200 ? 45.291 65.099 47.279 1.00 28.51 ? 236 ILE A O 1 ATOM 1655 C CB . ILE A 1 200 ? 44.914 62.055 47.068 1.00 28.88 ? 236 ILE A CB 1 ATOM 1656 C CG1 . ILE A 1 200 ? 46.281 61.608 47.606 1.00 26.97 ? 236 ILE A CG1 1 ATOM 1657 C CG2 . ILE A 1 200 ? 45.089 62.656 45.667 1.00 26.13 ? 236 ILE A CG2 1 ATOM 1658 C CD1 . ILE A 1 200 ? 46.233 60.776 48.913 1.00 26.54 ? 236 ILE A CD1 1 ATOM 1659 N N . GLU A 1 201 ? 45.845 64.355 49.335 1.00 27.98 ? 237 GLU A N 1 ATOM 1660 C CA . GLU A 1 201 ? 46.758 65.464 49.562 1.00 29.20 ? 237 GLU A CA 1 ATOM 1661 C C . GLU A 1 201 ? 48.125 64.911 49.875 1.00 28.20 ? 237 GLU A C 1 ATOM 1662 O O . GLU A 1 201 ? 48.239 63.922 50.583 1.00 25.69 ? 237 GLU A O 1 ATOM 1663 C CB . GLU A 1 201 ? 46.255 66.340 50.717 1.00 31.15 ? 237 GLU A CB 1 ATOM 1664 C CG . GLU A 1 201 ? 44.800 66.740 50.567 1.00 32.07 ? 237 GLU A CG 1 ATOM 1665 C CD . GLU A 1 201 ? 44.330 67.648 51.684 1.00 42.65 ? 237 GLU A CD 1 ATOM 1666 O OE1 . GLU A 1 201 ? 44.646 67.365 52.858 1.00 42.43 ? 237 GLU A OE1 1 ATOM 1667 O OE2 . GLU A 1 201 ? 43.644 68.642 51.392 1.00 44.04 ? 237 GLU A OE2 1 ATOM 1668 N N . TYR A 1 202 ? 49.164 65.531 49.334 1.00 26.85 ? 238 TYR A N 1 ATOM 1669 C CA . TYR A 1 202 ? 50.525 65.113 49.650 1.00 29.12 ? 238 TYR A CA 1 ATOM 1670 C C . TYR A 1 202 ? 51.466 66.287 49.468 1.00 28.03 ? 238 TYR A C 1 ATOM 1671 O O . TYR A 1 202 ? 51.124 67.255 48.781 1.00 24.68 ? 238 TYR A O 1 ATOM 1672 C CB . TYR A 1 202 ? 50.962 63.908 48.798 1.00 26.59 ? 238 TYR A CB 1 ATOM 1673 C CG . TYR A 1 202 ? 50.826 64.111 47.297 1.00 27.75 ? 238 TYR A CG 1 ATOM 1674 C CD1 . TYR A 1 202 ? 49.693 63.683 46.621 1.00 28.43 ? 238 TYR A CD1 1 ATOM 1675 C CD2 . TYR A 1 202 ? 51.838 64.710 46.555 1.00 27.76 ? 238 TYR A CD2 1 ATOM 1676 C CE1 . TYR A 1 202 ? 49.555 63.865 45.248 1.00 30.08 ? 238 TYR A CE1 1 ATOM 1677 C CE2 . TYR A 1 202 ? 51.712 64.890 45.176 1.00 29.01 ? 238 TYR A CE2 1 ATOM 1678 C CZ . TYR A 1 202 ? 50.566 64.464 44.531 1.00 28.71 ? 238 TYR A CZ 1 ATOM 1679 O OH . TYR A 1 202 ? 50.430 64.638 43.169 1.00 27.48 ? 238 TYR A OH 1 ATOM 1680 N N . SER A 1 203 ? 52.640 66.205 50.093 1.00 25.53 ? 239 SER A N 1 ATOM 1681 C CA . SER A 1 203 ? 53.626 67.282 50.028 1.00 27.89 ? 239 SER A CA 1 ATOM 1682 C C . SER A 1 203 ? 54.465 67.234 48.756 1.00 25.16 ? 239 SER A C 1 ATOM 1683 O O . SER A 1 203 ? 54.825 66.164 48.279 1.00 27.95 ? 239 SER A O 1 ATOM 1684 C CB . SER A 1 203 ? 54.567 67.220 51.239 1.00 27.59 ? 239 SER A CB 1 ATOM 1685 O OG . SER A 1 203 ? 53.862 67.333 52.461 1.00 31.02 ? 239 SER A OG 1 ATOM 1686 N N . PHE A 1 204 ? 54.783 68.402 48.215 1.00 25.52 ? 240 PHE A N 1 ATOM 1687 C CA . PHE A 1 204 ? 55.735 68.501 47.119 1.00 28.58 ? 240 PHE A CA 1 ATOM 1688 C C . PHE A 1 204 ? 56.818 69.464 47.602 1.00 28.75 ? 240 PHE A C 1 ATOM 1689 O O . PHE A 1 204 ? 56.513 70.578 48.024 1.00 31.21 ? 240 PHE A O 1 ATOM 1690 C CB . PHE A 1 204 ? 55.060 69.008 45.839 1.00 28.04 ? 240 PHE A CB 1 ATOM 1691 C CG . PHE A 1 204 ? 55.927 68.879 44.600 1.00 30.70 ? 240 PHE A CG 1 ATOM 1692 C CD1 . PHE A 1 204 ? 55.942 67.702 43.860 1.00 27.81 ? 240 PHE A CD1 1 ATOM 1693 C CD2 . PHE A 1 204 ? 56.734 69.927 44.194 1.00 31.88 ? 240 PHE A CD2 1 ATOM 1694 C CE1 . PHE A 1 204 ? 56.737 67.578 42.736 1.00 33.12 ? 240 PHE A CE1 1 ATOM 1695 C CE2 . PHE A 1 204 ? 57.536 69.815 43.064 1.00 36.38 ? 240 PHE A CE2 1 ATOM 1696 C CZ . PHE A 1 204 ? 57.538 68.635 42.335 1.00 34.50 ? 240 PHE A CZ 1 ATOM 1697 N N . TYR A 1 205 ? 58.075 69.032 47.580 1.00 26.68 ? 241 TYR A N 1 ATOM 1698 C CA . TYR A 1 205 ? 59.125 69.780 48.272 1.00 28.51 ? 241 TYR A CA 1 ATOM 1699 C C . TYR A 1 205 ? 59.781 70.830 47.385 1.00 31.50 ? 241 TYR A C 1 ATOM 1700 O O . TYR A 1 205 ? 60.213 71.871 47.878 1.00 25.52 ? 241 TYR A O 1 ATOM 1701 C CB . TYR A 1 205 ? 60.152 68.828 48.895 1.00 22.99 ? 241 TYR A CB 1 ATOM 1702 C CG . TYR A 1 205 ? 59.493 67.894 49.880 1.00 25.25 ? 241 TYR A CG 1 ATOM 1703 C CD1 . TYR A 1 205 ? 59.212 68.313 51.180 1.00 25.61 ? 241 TYR A CD1 1 ATOM 1704 C CD2 . TYR A 1 205 ? 59.088 66.630 49.496 1.00 22.86 ? 241 TYR A CD2 1 ATOM 1705 C CE1 . TYR A 1 205 ? 58.578 67.479 52.084 1.00 24.43 ? 241 TYR A CE1 1 ATOM 1706 C CE2 . TYR A 1 205 ? 58.449 65.788 50.388 1.00 28.46 ? 241 TYR A CE2 1 ATOM 1707 C CZ . TYR A 1 205 ? 58.201 66.220 51.683 1.00 26.43 ? 241 TYR A CZ 1 ATOM 1708 O OH . TYR A 1 205 ? 57.570 65.386 52.566 1.00 26.41 ? 241 TYR A OH 1 ATOM 1709 N N . SER A 1 206 ? 59.827 70.542 46.084 1.00 27.60 ? 242 SER A N 1 ATOM 1710 C CA . SER A 1 206 ? 60.328 71.478 45.069 1.00 30.46 ? 242 SER A CA 1 ATOM 1711 C C . SER A 1 206 ? 61.821 71.746 45.211 1.00 28.74 ? 242 SER A C 1 ATOM 1712 O O . SER A 1 206 ? 62.532 70.965 45.837 1.00 31.72 ? 242 SER A O 1 ATOM 1713 C CB . SER A 1 206 ? 59.521 72.785 45.087 1.00 30.02 ? 242 SER A CB 1 ATOM 1714 O OG . SER A 1 206 ? 59.827 73.602 43.975 1.00 31.97 ? 242 SER A OG 1 ATOM 1715 N N . ASP A 1 207 ? 62.302 72.821 44.591 1.00 28.33 ? 243 ASP A N 1 ATOM 1716 C CA . ASP A 1 207 ? 63.711 73.188 44.684 1.00 32.26 ? 243 ASP A CA 1 ATOM 1717 C C . ASP A 1 207 ? 64.070 73.558 46.117 1.00 31.77 ? 243 ASP A C 1 ATOM 1718 O O . ASP A 1 207 ? 63.223 74.048 46.860 1.00 30.17 ? 243 ASP A O 1 ATOM 1719 C CB . ASP A 1 207 ? 64.034 74.368 43.749 1.00 34.00 ? 243 ASP A CB 1 ATOM 1720 C CG . ASP A 1 207 ? 63.914 73.998 42.274 1.00 43.78 ? 243 ASP A CG 1 ATOM 1721 N N . GLU A 1 208 ? 65.327 73.324 46.485 1.00 35.36 ? 244 GLU A N 1 ATOM 1722 C CA . GLU A 1 208 ? 65.873 73.690 47.797 1.00 34.69 ? 244 GLU A CA 1 ATOM 1723 C C . GLU A 1 208 ? 65.386 75.044 48.278 1.00 36.83 ? 244 GLU A C 1 ATOM 1724 O O . GLU A 1 208 ? 65.158 75.240 49.470 1.00 36.17 ? 244 GLU A O 1 ATOM 1725 C CB . GLU A 1 208 ? 67.392 73.812 47.706 1.00 42.38 ? 244 GLU A CB 1 ATOM 1726 C CG . GLU A 1 208 ? 68.199 72.579 47.980 1.00 45.02 ? 244 GLU A CG 1 ATOM 1727 C CD . GLU A 1 208 ? 69.690 72.912 48.070 1.00 44.88 ? 244 GLU A CD 1 ATOM 1728 O OE1 . GLU A 1 208 ? 70.470 72.361 47.267 1.00 44.74 ? 244 GLU A OE1 1 ATOM 1729 O OE2 . GLU A 1 208 ? 70.077 73.726 48.947 1.00 44.30 ? 244 GLU A OE2 1 ATOM 1730 N N . SER A 1 209 ? 65.281 75.987 47.345 1.00 33.02 ? 245 SER A N 1 ATOM 1731 C CA . SER A 1 209 ? 64.992 77.384 47.662 1.00 35.70 ? 245 SER A CA 1 ATOM 1732 C C . SER A 1 209 ? 63.594 77.619 48.226 1.00 36.25 ? 245 SER A C 1 ATOM 1733 O O . SER A 1 209 ? 63.325 78.677 48.807 1.00 35.49 ? 245 SER A O 1 ATOM 1734 C CB . SER A 1 209 ? 65.154 78.230 46.405 1.00 33.56 ? 245 SER A CB 1 ATOM 1735 O OG . SER A 1 209 ? 64.218 77.802 45.431 1.00 41.20 ? 245 SER A OG 1 ATOM 1736 N N . LEU A 1 210 ? 62.702 76.649 48.035 1.00 33.57 ? 246 LEU A N 1 ATOM 1737 C CA . LEU A 1 210 ? 61.340 76.727 48.571 1.00 34.05 ? 246 LEU A CA 1 ATOM 1738 C C . LEU A 1 210 ? 61.366 76.457 50.074 1.00 31.05 ? 246 LEU A C 1 ATOM 1739 O O . LEU A 1 210 ? 61.682 75.345 50.503 1.00 30.63 ? 246 LEU A O 1 ATOM 1740 C CB . LEU A 1 210 ? 60.435 75.700 47.882 1.00 28.55 ? 246 LEU A CB 1 ATOM 1741 C CG . LEU A 1 210 ? 58.959 75.754 48.269 1.00 32.31 ? 246 LEU A CG 1 ATOM 1742 C CD1 . LEU A 1 210 ? 58.376 77.075 47.770 1.00 40.02 ? 246 LEU A CD1 1 ATOM 1743 C CD2 . LEU A 1 210 ? 58.174 74.565 47.690 1.00 31.38 ? 246 LEU A CD2 1 ATOM 1744 N N . GLN A 1 211 ? 61.036 77.466 50.874 1.00 28.37 ? 247 GLN A N 1 ATOM 1745 C CA . GLN A 1 211 ? 61.145 77.345 52.326 1.00 28.29 ? 247 GLN A CA 1 ATOM 1746 C C . GLN A 1 211 ? 60.065 76.434 52.966 1.00 28.73 ? 247 GLN A C 1 ATOM 1747 O O . GLN A 1 211 ? 60.360 75.648 53.883 1.00 25.67 ? 247 GLN A O 1 ATOM 1748 C CB . GLN A 1 211 ? 61.145 78.743 52.964 1.00 29.51 ? 247 GLN A CB 1 ATOM 1749 C CG . GLN A 1 211 ? 61.432 78.734 54.464 1.00 28.40 ? 247 GLN A CG 1 ATOM 1750 C CD . GLN A 1 211 ? 61.610 80.137 55.045 1.00 29.10 ? 247 GLN A CD 1 ATOM 1751 O OE1 . GLN A 1 211 ? 62.518 80.385 55.860 1.00 31.18 ? 247 GLN A OE1 1 ATOM 1752 N NE2 . GLN A 1 211 ? 60.745 81.053 54.642 1.00 25.39 ? 247 GLN A NE2 1 ATOM 1753 N N . TYR A 1 212 ? 58.824 76.542 52.490 1.00 25.72 ? 248 TYR A N 1 ATOM 1754 C CA . TYR A 1 212 ? 57.724 75.683 52.963 1.00 28.30 ? 248 TYR A CA 1 ATOM 1755 C C . TYR A 1 212 ? 57.261 74.740 51.853 1.00 31.04 ? 248 TYR A C 1 ATOM 1756 O O . TYR A 1 212 ? 57.004 75.182 50.742 1.00 27.50 ? 248 TYR A O 1 ATOM 1757 C CB . TYR A 1 212 ? 56.523 76.522 53.425 1.00 25.68 ? 248 TYR A CB 1 ATOM 1758 C CG . TYR A 1 212 ? 56.760 77.306 54.705 1.00 26.03 ? 248 TYR A CG 1 ATOM 1759 C CD1 . TYR A 1 212 ? 57.419 78.530 54.688 1.00 25.67 ? 248 TYR A CD1 1 ATOM 1760 C CD2 . TYR A 1 212 ? 56.328 76.809 55.936 1.00 28.11 ? 248 TYR A CD2 1 ATOM 1761 C CE1 . TYR A 1 212 ? 57.636 79.243 55.877 1.00 26.63 ? 248 TYR A CE1 1 ATOM 1762 C CE2 . TYR A 1 212 ? 56.528 77.506 57.106 1.00 22.28 ? 248 TYR A CE2 1 ATOM 1763 C CZ . TYR A 1 212 ? 57.184 78.717 57.080 1.00 26.21 ? 248 TYR A CZ 1 ATOM 1764 O OH . TYR A 1 212 ? 57.375 79.403 58.273 1.00 26.56 ? 248 TYR A OH 1 ATOM 1765 N N . PRO A 1 213 ? 57.154 73.436 52.150 1.00 29.41 ? 249 PRO A N 1 ATOM 1766 C CA . PRO A 1 213 ? 56.665 72.477 51.149 1.00 29.30 ? 249 PRO A CA 1 ATOM 1767 C C . PRO A 1 213 ? 55.264 72.842 50.676 1.00 31.98 ? 249 PRO A C 1 ATOM 1768 O O . PRO A 1 213 ? 54.501 73.391 51.474 1.00 30.51 ? 249 PRO A O 1 ATOM 1769 C CB . PRO A 1 213 ? 56.618 71.158 51.925 1.00 28.98 ? 249 PRO A CB 1 ATOM 1770 C CG . PRO A 1 213 ? 57.611 71.328 53.005 1.00 29.92 ? 249 PRO A CG 1 ATOM 1771 C CD . PRO A 1 213 ? 57.543 72.774 53.407 1.00 30.02 ? 249 PRO A CD 1 ATOM 1772 N N . LYS A 1 214 ? 54.938 72.564 49.408 1.00 32.95 ? 250 LYS A N 1 ATOM 1773 C CA . LYS A 1 214 ? 53.579 72.770 48.895 1.00 30.50 ? 250 LYS A CA 1 ATOM 1774 C C . LYS A 1 214 ? 52.730 71.531 49.167 1.00 30.33 ? 250 LYS A C 1 ATOM 1775 O O . LYS A 1 214 ? 53.227 70.415 49.094 1.00 31.04 ? 250 LYS A O 1 ATOM 1776 C CB . LYS A 1 214 ? 53.587 73.005 47.376 1.00 32.44 ? 250 LYS A CB 1 ATOM 1777 C CG . LYS A 1 214 ? 54.432 74.179 46.908 1.00 40.78 ? 250 LYS A CG 1 ATOM 1778 C CD . LYS A 1 214 ? 54.554 74.199 45.378 1.00 44.81 ? 250 LYS A CD 1 ATOM 1779 N N . THR A 1 215 ? 51.448 71.725 49.447 1.00 27.89 ? 251 THR A N 1 ATOM 1780 C CA . THR A 1 215 ? 50.515 70.613 49.493 1.00 28.66 ? 251 THR A CA 1 ATOM 1781 C C . THR A 1 215 ? 49.765 70.491 48.171 1.00 32.58 ? 251 THR A C 1 ATOM 1782 O O . THR A 1 215 ? 49.018 71.394 47.778 1.00 33.48 ? 251 THR A O 1 ATOM 1783 C CB . THR A 1 215 ? 49.500 70.754 50.647 1.00 34.43 ? 251 THR A CB 1 ATOM 1784 O OG1 . THR A 1 215 ? 50.205 70.863 51.882 1.00 31.76 ? 251 THR A OG1 1 ATOM 1785 C CG2 . THR A 1 215 ? 48.604 69.523 50.711 1.00 32.79 ? 251 THR A CG2 1 ATOM 1786 N N . VAL A 1 216 ? 49.968 69.375 47.478 1.00 29.11 ? 252 VAL A N 1 ATOM 1787 C CA . VAL A 1 216 ? 49.201 69.099 46.267 1.00 27.71 ? 252 VAL A CA 1 ATOM 1788 C C . VAL A 1 216 ? 47.871 68.465 46.668 1.00 31.75 ? 252 VAL A C 1 ATOM 1789 O O . VAL A 1 216 ? 47.834 67.578 47.524 1.00 31.35 ? 252 VAL A O 1 ATOM 1790 C CB . VAL A 1 216 ? 49.967 68.157 45.323 1.00 29.41 ? 252 VAL A CB 1 ATOM 1791 C CG1 . VAL A 1 216 ? 49.159 67.904 44.055 1.00 32.15 ? 252 VAL A CG1 1 ATOM 1792 C CG2 . VAL A 1 216 ? 51.327 68.763 44.955 1.00 30.47 ? 252 VAL A CG2 1 ATOM 1793 N N . ARG A 1 217 ? 46.780 68.936 46.076 1.00 27.79 ? 253 ARG A N 1 ATOM 1794 C CA . ARG A 1 217 ? 45.456 68.358 46.311 1.00 27.57 ? 253 ARG A CA 1 ATOM 1795 C C . ARG A 1 217 ? 44.836 67.987 44.970 1.00 31.16 ? 253 ARG A C 1 ATOM 1796 O O . ARG A 1 217 ? 44.742 68.824 44.069 1.00 31.21 ? 253 ARG A O 1 ATOM 1797 C CB . ARG A 1 217 ? 44.553 69.359 47.032 1.00 30.70 ? 253 ARG A CB 1 ATOM 1798 C CG . ARG A 1 217 ? 45.182 69.919 48.311 1.00 37.92 ? 253 ARG A CG 1 ATOM 1799 C CD . ARG A 1 217 ? 44.286 70.948 48.980 1.00 43.94 ? 253 ARG A CD 1 ATOM 1800 N NE . ARG A 1 217 ? 45.069 71.923 49.748 1.00 58.22 ? 253 ARG A NE 1 ATOM 1801 C CZ . ARG A 1 217 ? 45.690 71.649 50.896 1.00 55.95 ? 253 ARG A CZ 1 ATOM 1802 N NH1 . ARG A 1 217 ? 45.624 70.419 51.395 1.00 57.37 ? 253 ARG A NH1 1 ATOM 1803 N NH2 . ARG A 1 217 ? 46.378 72.593 51.547 1.00 52.15 ? 253 ARG A NH2 1 ATOM 1804 N N . VAL A 1 218 ? 44.432 66.731 44.829 1.00 27.47 ? 254 VAL A N 1 ATOM 1805 C CA . VAL A 1 218 ? 43.855 66.256 43.576 1.00 27.17 ? 254 VAL A CA 1 ATOM 1806 C C . VAL A 1 218 ? 42.551 65.536 43.898 1.00 25.08 ? 254 VAL A C 1 ATOM 1807 O O . VAL A 1 218 ? 42.530 64.709 44.793 1.00 26.91 ? 254 VAL A O 1 ATOM 1808 C CB . VAL A 1 218 ? 44.803 65.236 42.900 1.00 28.68 ? 254 VAL A CB 1 ATOM 1809 C CG1 . VAL A 1 218 ? 44.309 64.872 41.490 1.00 26.22 ? 254 VAL A CG1 1 ATOM 1810 C CG2 . VAL A 1 218 ? 46.210 65.777 42.848 1.00 30.46 ? 254 VAL A CG2 1 ATOM 1811 N N . PRO A 1 219 ? 41.459 65.844 43.175 1.00 28.01 ? 255 PRO A N 1 ATOM 1812 C CA . PRO A 1 219 ? 40.240 65.055 43.366 1.00 26.00 ? 255 PRO A CA 1 ATOM 1813 C C . PRO A 1 219 ? 40.490 63.655 42.842 1.00 28.83 ? 255 PRO A C 1 ATOM 1814 O O . PRO A 1 219 ? 40.833 63.481 41.677 1.00 29.69 ? 255 PRO A O 1 ATOM 1815 C CB . PRO A 1 219 ? 39.214 65.781 42.490 1.00 26.68 ? 255 PRO A CB 1 ATOM 1816 C CG . PRO A 1 219 ? 39.767 67.161 42.332 1.00 29.53 ? 255 PRO A CG 1 ATOM 1817 C CD . PRO A 1 219 ? 41.238 66.969 42.252 1.00 30.39 ? 255 PRO A CD 1 ATOM 1818 N N . TYR A 1 220 ? 40.337 62.674 43.712 1.00 25.25 ? 256 TYR A N 1 ATOM 1819 C CA . TYR A 1 220 ? 40.754 61.321 43.430 1.00 24.61 ? 256 TYR A CA 1 ATOM 1820 C C . TYR A 1 220 ? 39.829 60.423 44.235 1.00 26.14 ? 256 TYR A C 1 ATOM 1821 O O . TYR A 1 220 ? 39.929 60.382 45.464 1.00 25.38 ? 256 TYR A O 1 ATOM 1822 C CB . TYR A 1 220 ? 42.198 61.137 43.903 1.00 23.07 ? 256 TYR A CB 1 ATOM 1823 C CG . TYR A 1 220 ? 42.795 59.773 43.638 1.00 23.27 ? 256 TYR A CG 1 ATOM 1824 C CD1 . TYR A 1 220 ? 42.336 58.651 44.309 1.00 24.29 ? 256 TYR A CD1 1 ATOM 1825 C CD2 . TYR A 1 220 ? 43.843 59.612 42.735 1.00 20.45 ? 256 TYR A CD2 1 ATOM 1826 C CE1 . TYR A 1 220 ? 42.891 57.389 44.068 1.00 23.75 ? 256 TYR A CE1 1 ATOM 1827 C CE2 . TYR A 1 220 ? 44.412 58.360 42.499 1.00 21.56 ? 256 TYR A CE2 1 ATOM 1828 C CZ . TYR A 1 220 ? 43.924 57.256 43.170 1.00 23.11 ? 256 TYR A CZ 1 ATOM 1829 O OH . TYR A 1 220 ? 44.469 56.007 42.955 1.00 24.77 ? 256 TYR A OH 1 ATOM 1830 N N . PRO A 1 221 ? 38.910 59.712 43.554 1.00 25.66 ? 257 PRO A N 1 ATOM 1831 C CA . PRO A 1 221 ? 37.996 58.824 44.276 1.00 23.65 ? 257 PRO A CA 1 ATOM 1832 C C . PRO A 1 221 ? 38.690 57.506 44.552 1.00 25.98 ? 257 PRO A C 1 ATOM 1833 O O . PRO A 1 221 ? 39.072 56.820 43.607 1.00 25.18 ? 257 PRO A O 1 ATOM 1834 C CB . PRO A 1 221 ? 36.861 58.601 43.272 1.00 24.90 ? 257 PRO A CB 1 ATOM 1835 C CG . PRO A 1 221 ? 37.540 58.694 41.924 1.00 22.99 ? 257 PRO A CG 1 ATOM 1836 C CD . PRO A 1 221 ? 38.635 59.740 42.100 1.00 27.48 ? 257 PRO A CD 1 ATOM 1837 N N . LYS A 1 222 ? 38.875 57.170 45.824 1.00 25.65 ? 258 LYS A N 1 ATOM 1838 C CA . LYS A 1 222 ? 39.380 55.859 46.188 1.00 23.16 ? 258 LYS A CA 1 ATOM 1839 C C . LYS A 1 222 ? 38.201 54.884 46.221 1.00 26.30 ? 258 LYS A C 1 ATOM 1840 O O . LYS A 1 222 ? 37.050 55.291 46.073 1.00 23.72 ? 258 LYS A O 1 ATOM 1841 C CB . LYS A 1 222 ? 40.126 55.912 47.527 1.00 25.53 ? 258 LYS A CB 1 ATOM 1842 C CG . LYS A 1 222 ? 41.428 56.744 47.470 1.00 24.73 ? 258 LYS A CG 1 ATOM 1843 C CD . LYS A 1 222 ? 41.988 57.002 48.858 1.00 23.41 ? 258 LYS A CD 1 ATOM 1844 C CE . LYS A 1 222 ? 43.285 57.796 48.815 1.00 23.44 ? 258 LYS A CE 1 ATOM 1845 N NZ . LYS A 1 222 ? 44.446 56.924 48.504 1.00 22.83 ? 258 LYS A NZ 1 ATOM 1846 N N . ALA A 1 223 ? 38.488 53.601 46.377 1.00 23.92 ? 259 ALA A N 1 ATOM 1847 C CA . ALA A 1 223 ? 37.472 52.595 46.158 1.00 26.82 ? 259 ALA A CA 1 ATOM 1848 C C . ALA A 1 223 ? 36.299 52.872 47.081 1.00 30.47 ? 259 ALA A C 1 ATOM 1849 O O . ALA A 1 223 ? 36.474 53.066 48.280 1.00 30.93 ? 259 ALA A O 1 ATOM 1850 C CB . ALA A 1 223 ? 38.032 51.195 46.392 1.00 24.87 ? 259 ALA A CB 1 ATOM 1851 N N . GLY A 1 224 ? 35.102 52.919 46.514 1.00 27.38 ? 260 GLY A N 1 ATOM 1852 C CA . GLY A 1 224 ? 33.905 53.100 47.310 1.00 28.38 ? 260 GLY A CA 1 ATOM 1853 C C . GLY A 1 224 ? 33.542 54.540 47.610 1.00 30.64 ? 260 GLY A C 1 ATOM 1854 O O . GLY A 1 224 ? 32.476 54.782 48.150 1.00 32.13 ? 260 GLY A O 1 ATOM 1855 N N . ALA A 1 225 ? 34.395 55.495 47.245 1.00 27.10 ? 261 ALA A N 1 ATOM 1856 C CA . ALA A 1 225 ? 34.128 56.900 47.571 1.00 30.54 ? 261 ALA A CA 1 ATOM 1857 C C . ALA A 1 225 ? 33.313 57.574 46.490 1.00 30.38 ? 261 ALA A C 1 ATOM 1858 O O . ALA A 1 225 ? 33.060 56.980 45.451 1.00 31.37 ? 261 ALA A O 1 ATOM 1859 C CB . ALA A 1 225 ? 35.433 57.667 47.822 1.00 28.79 ? 261 ALA A CB 1 ATOM 1860 N N . VAL A 1 226 ? 32.906 58.816 46.729 1.00 28.87 ? 262 VAL A N 1 ATOM 1861 C CA . VAL A 1 226 ? 32.081 59.524 45.760 1.00 29.05 ? 262 VAL A CA 1 ATOM 1862 C C . VAL A 1 226 ? 32.859 59.763 44.474 1.00 30.82 ? 262 VAL A C 1 ATOM 1863 O O . VAL A 1 226 ? 33.944 60.340 44.521 1.00 29.55 ? 262 VAL A O 1 ATOM 1864 C CB . VAL A 1 226 ? 31.607 60.885 46.299 1.00 28.97 ? 262 VAL A CB 1 ATOM 1865 C CG1 . VAL A 1 226 ? 30.912 61.675 45.199 1.00 29.72 ? 262 VAL A CG1 1 ATOM 1866 C CG2 . VAL A 1 226 ? 30.678 60.696 47.501 1.00 33.69 ? 262 VAL A CG2 1 ATOM 1867 N N . ASN A 1 227 ? 32.294 59.326 43.339 1.00 30.57 ? 263 ASN A N 1 ATOM 1868 C CA . ASN A 1 227 ? 32.899 59.468 42.008 1.00 29.71 ? 263 ASN A CA 1 ATOM 1869 C C . ASN A 1 227 ? 32.456 60.762 41.365 1.00 29.81 ? 263 ASN A C 1 ATOM 1870 O O . ASN A 1 227 ? 31.419 61.298 41.731 1.00 28.84 ? 263 ASN A O 1 ATOM 1871 C CB . ASN A 1 227 ? 32.415 58.336 41.083 1.00 28.82 ? 263 ASN A CB 1 ATOM 1872 C CG . ASN A 1 227 ? 33.390 57.192 40.998 1.00 30.52 ? 263 ASN A CG 1 ATOM 1873 O OD1 . ASN A 1 227 ? 34.547 57.345 41.366 1.00 32.30 ? 263 ASN A OD1 1 ATOM 1874 N ND2 . ASN A 1 227 ? 32.939 56.040 40.480 1.00 25.78 ? 263 ASN A ND2 1 ATOM 1875 N N . PRO A 1 228 ? 33.205 61.243 40.360 1.00 27.50 ? 264 PRO A N 1 ATOM 1876 C CA . PRO A 1 228 ? 32.734 62.375 39.561 1.00 30.11 ? 264 PRO A CA 1 ATOM 1877 C C . PRO A 1 228 ? 31.459 62.017 38.789 1.00 31.23 ? 264 PRO A C 1 ATOM 1878 O O . PRO A 1 228 ? 31.190 60.842 38.541 1.00 28.25 ? 264 PRO A O 1 ATOM 1879 C CB . PRO A 1 228 ? 33.883 62.599 38.566 1.00 27.73 ? 264 PRO A CB 1 ATOM 1880 C CG . PRO A 1 228 ? 34.517 61.270 38.429 1.00 27.37 ? 264 PRO A CG 1 ATOM 1881 C CD . PRO A 1 228 ? 34.472 60.711 39.842 1.00 29.89 ? 264 PRO A CD 1 ATOM 1882 N N . THR A 1 229 ? 30.674 63.023 38.418 1.00 29.39 ? 265 THR A N 1 ATOM 1883 C CA . THR A 1 229 ? 29.527 62.776 37.558 1.00 29.11 ? 265 THR A CA 1 ATOM 1884 C C . THR A 1 229 ? 29.812 63.357 36.192 1.00 28.93 ? 265 THR A C 1 ATOM 1885 O O . THR A 1 229 ? 30.646 64.249 36.060 1.00 29.22 ? 265 THR A O 1 ATOM 1886 C CB . THR A 1 229 ? 28.235 63.391 38.121 1.00 30.95 ? 265 THR A CB 1 ATOM 1887 O OG1 . THR A 1 229 ? 28.392 64.816 38.240 1.00 34.83 ? 265 THR A OG1 1 ATOM 1888 C CG2 . THR A 1 229 ? 27.913 62.785 39.492 1.00 33.73 ? 265 THR A CG2 1 ATOM 1889 N N . VAL A 1 230 ? 29.105 62.851 35.182 1.00 31.07 ? 266 VAL A N 1 ATOM 1890 C CA . VAL A 1 230 ? 29.409 63.168 33.797 1.00 27.43 ? 266 VAL A CA 1 ATOM 1891 C C . VAL A 1 230 ? 28.129 63.536 33.047 1.00 31.07 ? 266 VAL A C 1 ATOM 1892 O O . VAL A 1 230 ? 27.057 62.984 33.331 1.00 29.90 ? 266 VAL A O 1 ATOM 1893 C CB . VAL A 1 230 ? 30.094 61.980 33.096 1.00 28.31 ? 266 VAL A CB 1 ATOM 1894 C CG1 . VAL A 1 230 ? 29.169 60.760 33.075 1.00 29.05 ? 266 VAL A CG1 1 ATOM 1895 C CG2 . VAL A 1 230 ? 30.500 62.358 31.680 1.00 26.38 ? 266 VAL A CG2 1 ATOM 1896 N N . LYS A 1 231 ? 28.251 64.498 32.129 1.00 28.87 ? 267 LYS A N 1 ATOM 1897 C CA . LYS A 1 231 ? 27.196 64.849 31.173 1.00 29.93 ? 267 LYS A CA 1 ATOM 1898 C C . LYS A 1 231 ? 27.801 64.857 29.776 1.00 32.37 ? 267 LYS A C 1 ATOM 1899 O O . LYS A 1 231 ? 29.012 65.017 29.643 1.00 34.04 ? 267 LYS A O 1 ATOM 1900 C CB . LYS A 1 231 ? 26.632 66.241 31.467 1.00 30.30 ? 267 LYS A CB 1 ATOM 1901 C CG . LYS A 1 231 ? 25.805 66.320 32.736 1.00 32.96 ? 267 LYS A CG 1 ATOM 1902 C CD . LYS A 1 231 ? 25.280 67.726 32.954 1.00 34.24 ? 267 LYS A CD 1 ATOM 1903 C CE . LYS A 1 231 ? 24.514 67.816 34.278 1.00 36.83 ? 267 LYS A CE 1 ATOM 1904 N NZ . LYS A 1 231 ? 23.811 69.123 34.405 1.00 42.11 ? 267 LYS A NZ 1 ATOM 1905 N N . PHE A 1 232 ? 26.967 64.719 28.742 1.00 31.88 ? 268 PHE A N 1 ATOM 1906 C CA . PHE A 1 232 ? 27.440 64.743 27.358 1.00 33.01 ? 268 PHE A CA 1 ATOM 1907 C C . PHE A 1 232 ? 26.694 65.792 26.503 1.00 34.56 ? 268 PHE A C 1 ATOM 1908 O O . PHE A 1 232 ? 25.472 65.884 26.560 1.00 35.29 ? 268 PHE A O 1 ATOM 1909 C CB . PHE A 1 232 ? 27.308 63.344 26.738 1.00 31.78 ? 268 PHE A CB 1 ATOM 1910 C CG . PHE A 1 232 ? 28.031 63.189 25.434 1.00 34.78 ? 268 PHE A CG 1 ATOM 1911 C CD1 . PHE A 1 232 ? 27.347 63.269 24.234 1.00 34.58 ? 268 PHE A CD1 1 ATOM 1912 C CD2 . PHE A 1 232 ? 29.401 62.957 25.406 1.00 30.80 ? 268 PHE A CD2 1 ATOM 1913 C CE1 . PHE A 1 232 ? 28.007 63.127 23.026 1.00 32.27 ? 268 PHE A CE1 1 ATOM 1914 C CE2 . PHE A 1 232 ? 30.072 62.812 24.190 1.00 33.82 ? 268 PHE A CE2 1 ATOM 1915 C CZ . PHE A 1 232 ? 29.370 62.902 23.000 1.00 31.99 ? 268 PHE A CZ 1 ATOM 1916 N N . PHE A 1 233 ? 27.431 66.574 25.720 1.00 30.86 ? 269 PHE A N 1 ATOM 1917 C CA . PHE A 1 233 ? 26.833 67.627 24.905 1.00 32.23 ? 269 PHE A CA 1 ATOM 1918 C C . PHE A 1 233 ? 27.310 67.575 23.454 1.00 33.48 ? 269 PHE A C 1 ATOM 1919 O O . PHE A 1 233 ? 28.355 67.011 23.157 1.00 33.18 ? 269 PHE A O 1 ATOM 1920 C CB . PHE A 1 233 ? 27.177 69.008 25.483 1.00 33.88 ? 269 PHE A CB 1 ATOM 1921 C CG . PHE A 1 233 ? 26.711 69.218 26.897 1.00 36.07 ? 269 PHE A CG 1 ATOM 1922 C CD1 . PHE A 1 233 ? 25.478 69.797 27.159 1.00 38.14 ? 269 PHE A CD1 1 ATOM 1923 C CD2 . PHE A 1 233 ? 27.516 68.862 27.965 1.00 36.12 ? 269 PHE A CD2 1 ATOM 1924 C CE1 . PHE A 1 233 ? 25.053 70.001 28.460 1.00 37.66 ? 269 PHE A CE1 1 ATOM 1925 C CE2 . PHE A 1 233 ? 27.099 69.057 29.261 1.00 32.79 ? 269 PHE A CE2 1 ATOM 1926 C CZ . PHE A 1 233 ? 25.864 69.627 29.515 1.00 37.04 ? 269 PHE A CZ 1 ATOM 1927 N N . VAL A 1 234 ? 26.553 68.199 22.553 1.00 33.79 ? 270 VAL A N 1 ATOM 1928 C CA . VAL A 1 234 ? 26.964 68.332 21.160 1.00 30.59 ? 270 VAL A CA 1 ATOM 1929 C C . VAL A 1 234 ? 26.612 69.725 20.652 1.00 32.45 ? 270 VAL A C 1 ATOM 1930 O O . VAL A 1 234 ? 25.483 70.170 20.803 1.00 33.31 ? 270 VAL A O 1 ATOM 1931 C CB . VAL A 1 234 ? 26.266 67.291 20.267 1.00 33.44 ? 270 VAL A CB 1 ATOM 1932 C CG1 . VAL A 1 234 ? 26.723 67.433 18.812 1.00 31.95 ? 270 VAL A CG1 1 ATOM 1933 C CG2 . VAL A 1 234 ? 26.513 65.897 20.796 1.00 27.15 ? 270 VAL A CG2 1 ATOM 1934 N N . VAL A 1 235 ? 27.583 70.411 20.057 1.00 35.46 ? 271 VAL A N 1 ATOM 1935 C CA . VAL A 1 235 ? 27.391 71.773 19.575 1.00 33.53 ? 271 VAL A CA 1 ATOM 1936 C C . VAL A 1 235 ? 27.552 71.826 18.061 1.00 41.43 ? 271 VAL A C 1 ATOM 1937 O O . VAL A 1 235 ? 28.478 71.219 17.501 1.00 37.65 ? 271 VAL A O 1 ATOM 1938 C CB . VAL A 1 235 ? 28.431 72.749 20.185 1.00 40.46 ? 271 VAL A CB 1 ATOM 1939 C CG1 . VAL A 1 235 ? 28.154 74.175 19.741 1.00 39.64 ? 271 VAL A CG1 1 ATOM 1940 C CG2 . VAL A 1 235 ? 28.432 72.670 21.696 1.00 42.59 ? 271 VAL A CG2 1 ATOM 1941 N N . ASN A 1 236 ? 26.655 72.549 17.394 1.00 40.92 ? 272 ASN A N 1 ATOM 1942 C CA . ASN A 1 236 ? 26.829 72.815 15.977 1.00 40.40 ? 272 ASN A CA 1 ATOM 1943 C C . ASN A 1 236 ? 27.808 73.956 15.777 1.00 39.75 ? 272 ASN A C 1 ATOM 1944 O O . ASN A 1 236 ? 27.557 75.085 16.181 1.00 44.32 ? 272 ASN A O 1 ATOM 1945 C CB . ASN A 1 236 ? 25.501 73.136 15.295 1.00 44.52 ? 272 ASN A CB 1 ATOM 1946 C CG . ASN A 1 236 ? 25.599 73.063 13.779 1.00 43.72 ? 272 ASN A CG 1 ATOM 1947 O OD1 . ASN A 1 236 ? 26.631 73.401 13.188 1.00 43.61 ? 272 ASN A OD1 1 ATOM 1948 N ND2 . ASN A 1 236 ? 24.531 72.605 13.146 1.00 43.94 ? 272 ASN A ND2 1 ATOM 1949 N N . THR A 1 237 ? 28.920 73.641 15.136 1.00 37.23 ? 273 THR A N 1 ATOM 1950 C CA . THR A 1 237 ? 30.022 74.557 14.958 1.00 36.64 ? 273 THR A CA 1 ATOM 1951 C C . THR A 1 237 ? 29.813 75.459 13.738 1.00 48.16 ? 273 THR A C 1 ATOM 1952 O O . THR A 1 237 ? 30.485 76.481 13.588 1.00 47.24 ? 273 THR A O 1 ATOM 1953 C CB . THR A 1 237 ? 31.311 73.739 14.792 1.00 42.51 ? 273 THR A CB 1 ATOM 1954 O OG1 . THR A 1 237 ? 31.888 73.499 16.084 1.00 46.72 ? 273 THR A OG1 1 ATOM 1955 C CG2 . THR A 1 237 ? 32.306 74.442 13.911 1.00 45.79 ? 273 THR A CG2 1 ATOM 1956 N N . ASP A 1 238 ? 28.879 75.082 12.868 1.00 46.55 ? 274 ASP A N 1 ATOM 1957 C CA . ASP A 1 238 ? 28.635 75.845 11.646 1.00 50.89 ? 274 ASP A CA 1 ATOM 1958 C C . ASP A 1 238 ? 27.773 77.081 11.913 1.00 52.82 ? 274 ASP A C 1 ATOM 1959 O O . ASP A 1 238 ? 27.819 78.057 11.160 1.00 55.79 ? 274 ASP A O 1 ATOM 1960 C CB . ASP A 1 238 ? 27.983 74.967 10.563 1.00 49.35 ? 274 ASP A CB 1 ATOM 1961 C CG . ASP A 1 238 ? 28.971 74.006 9.899 1.00 54.60 ? 274 ASP A CG 1 ATOM 1962 O OD1 . ASP A 1 238 ? 30.204 74.258 9.950 1.00 48.44 ? 274 ASP A OD1 1 ATOM 1963 O OD2 . ASP A 1 238 ? 28.503 73.002 9.304 1.00 56.10 ? 274 ASP A OD2 1 ATOM 1964 N N . SER A 1 239 ? 26.997 77.040 12.991 1.00 52.67 ? 275 SER A N 1 ATOM 1965 C CA . SER A 1 239 ? 26.072 78.130 13.306 1.00 57.37 ? 275 SER A CA 1 ATOM 1966 C C . SER A 1 239 ? 26.462 78.933 14.555 1.00 52.26 ? 275 SER A C 1 ATOM 1967 O O . SER A 1 239 ? 25.606 79.285 15.366 1.00 53.88 ? 275 SER A O 1 ATOM 1968 C CB . SER A 1 239 ? 24.645 77.588 13.455 1.00 55.75 ? 275 SER A CB 1 ATOM 1969 O OG . SER A 1 239 ? 24.563 76.661 14.524 1.00 51.22 ? 275 SER A OG 1 ATOM 1970 N N . LEU A 1 240 ? 27.749 79.225 14.709 1.00 52.49 ? 276 LEU A N 1 ATOM 1971 C CA . LEU A 1 240 ? 28.197 80.019 15.845 1.00 54.78 ? 276 LEU A CA 1 ATOM 1972 C C . LEU A 1 240 ? 28.062 81.508 15.540 1.00 56.01 ? 276 LEU A C 1 ATOM 1973 O O . LEU A 1 240 ? 28.280 81.937 14.407 1.00 51.09 ? 276 LEU A O 1 ATOM 1974 C CB . LEU A 1 240 ? 29.639 79.671 16.228 1.00 49.81 ? 276 LEU A CB 1 ATOM 1975 C CG . LEU A 1 240 ? 29.866 78.275 16.814 1.00 42.27 ? 276 LEU A CG 1 ATOM 1976 C CD1 . LEU A 1 240 ? 31.331 78.049 17.063 1.00 44.92 ? 276 LEU A CD1 1 ATOM 1977 C CD2 . LEU A 1 240 ? 29.084 78.092 18.088 1.00 40.89 ? 276 LEU A CD2 1 ATOM 1978 N N . SER A 1 241 ? 27.695 82.285 16.558 1.00 60.05 ? 277 SER A N 1 ATOM 1979 C CA . SER A 1 241 ? 27.505 83.724 16.410 1.00 60.57 ? 277 SER A CA 1 ATOM 1980 C C . SER A 1 241 ? 28.425 84.516 17.326 1.00 62.50 ? 277 SER A C 1 ATOM 1981 O O . SER A 1 241 ? 28.775 84.066 18.418 1.00 60.02 ? 277 SER A O 1 ATOM 1982 C CB . SER A 1 241 ? 26.052 84.105 16.705 1.00 65.81 ? 277 SER A CB 1 ATOM 1983 O OG . SER A 1 241 ? 25.880 85.513 16.707 1.00 65.02 ? 277 SER A OG 1 ATOM 1984 N N . SER A 1 242 ? 28.801 85.707 16.874 1.00 62.42 ? 278 SER A N 1 ATOM 1985 C CA . SER A 1 242 ? 29.575 86.636 17.688 1.00 66.17 ? 278 SER A CA 1 ATOM 1986 C C . SER A 1 242 ? 28.671 87.365 18.693 1.00 66.05 ? 278 SER A C 1 ATOM 1987 O O . SER A 1 242 ? 29.148 88.076 19.577 1.00 66.19 ? 278 SER A O 1 ATOM 1988 C CB . SER A 1 242 ? 30.280 87.656 16.788 1.00 69.51 ? 278 SER A CB 1 ATOM 1989 O OG . SER A 1 242 ? 30.624 87.085 15.532 1.00 72.56 ? 278 SER A OG 1 ATOM 1990 N N . VAL A 1 243 ? 27.362 87.184 18.548 1.00 67.45 ? 279 VAL A N 1 ATOM 1991 C CA . VAL A 1 243 ? 26.383 87.861 19.398 1.00 68.25 ? 279 VAL A CA 1 ATOM 1992 C C . VAL A 1 243 ? 25.899 86.967 20.540 1.00 70.12 ? 279 VAL A C 1 ATOM 1993 O O . VAL A 1 243 ? 26.163 87.245 21.713 1.00 71.34 ? 279 VAL A O 1 ATOM 1994 C CB . VAL A 1 243 ? 25.163 88.332 18.581 1.00 65.79 ? 279 VAL A CB 1 ATOM 1995 C CG1 . VAL A 1 243 ? 24.080 88.863 19.504 1.00 72.61 ? 279 VAL A CG1 1 ATOM 1996 C CG2 . VAL A 1 243 ? 25.577 89.387 17.572 1.00 62.13 ? 279 VAL A CG2 1 ATOM 1997 N N . THR A 1 244 ? 25.188 85.896 20.189 1.00 70.09 ? 280 THR A N 1 ATOM 1998 C CA . THR A 1 244 ? 24.673 84.954 21.181 1.00 69.30 ? 280 THR A CA 1 ATOM 1999 C C . THR A 1 244 ? 25.683 83.847 21.449 1.00 66.87 ? 280 THR A C 1 ATOM 2000 O O . THR A 1 244 ? 26.557 83.582 20.625 1.00 66.14 ? 280 THR A O 1 ATOM 2001 C CB . THR A 1 244 ? 23.351 84.303 20.716 1.00 74.18 ? 280 THR A CB 1 ATOM 2002 O OG1 . THR A 1 244 ? 22.589 85.248 19.953 1.00 72.34 ? 280 THR A OG1 1 ATOM 2003 C CG2 . THR A 1 244 ? 22.529 83.827 21.919 1.00 72.93 ? 280 THR A CG2 1 ATOM 2004 N N . ASN A 1 245 ? 25.562 83.198 22.601 1.00 64.72 ? 281 ASN A N 1 ATOM 2005 C CA . ASN A 1 245 ? 26.448 82.091 22.931 1.00 63.75 ? 281 ASN A CA 1 ATOM 2006 C C . ASN A 1 245 ? 26.050 80.813 22.222 1.00 63.47 ? 281 ASN A C 1 ATOM 2007 O O . ASN A 1 245 ? 24.912 80.656 21.776 1.00 62.70 ? 281 ASN A O 1 ATOM 2008 C CB . ASN A 1 245 ? 26.464 81.833 24.430 1.00 64.42 ? 281 ASN A CB 1 ATOM 2009 C CG . ASN A 1 245 ? 26.605 83.092 25.223 1.00 63.87 ? 281 ASN A CG 1 ATOM 2010 O OD1 . ASN A 1 245 ? 27.564 83.846 25.057 1.00 59.66 ? 281 ASN A OD1 1 ATOM 2011 N ND2 . ASN A 1 245 ? 25.629 83.349 26.081 1.00 67.43 ? 281 ASN A ND2 1 ATOM 2012 N N . ALA A 1 246 ? 27.006 79.899 22.131 1.00 60.72 ? 282 ALA A N 1 ATOM 2013 C CA . ALA A 1 246 ? 26.771 78.605 21.526 1.00 56.35 ? 282 ALA A CA 1 ATOM 2014 C C . ALA A 1 246 ? 25.635 77.901 22.245 1.00 54.43 ? 282 ALA A C 1 ATOM 2015 O O . ALA A 1 246 ? 25.493 78.021 23.459 1.00 53.78 ? 282 ALA A O 1 ATOM 2016 C CB . ALA A 1 246 ? 28.031 77.766 21.596 1.00 50.54 ? 282 ALA A CB 1 ATOM 2017 N N . THR A 1 247 ? 24.828 77.167 21.490 1.00 52.34 ? 283 THR A N 1 ATOM 2018 C CA . THR A 1 247 ? 23.785 76.352 22.085 1.00 53.03 ? 283 THR A CA 1 ATOM 2019 C C . THR A 1 247 ? 24.215 74.899 22.109 1.00 49.53 ? 283 THR A C 1 ATOM 2020 O O . THR A 1 247 ? 24.241 74.239 21.076 1.00 50.22 ? 283 THR A O 1 ATOM 2021 C CB . THR A 1 247 ? 22.472 76.455 21.309 1.00 56.56 ? 283 THR A CB 1 ATOM 2022 O OG1 . THR A 1 247 ? 22.032 77.820 21.294 1.00 61.96 ? 283 THR A OG1 1 ATOM 2023 C CG2 . THR A 1 247 ? 21.411 75.585 21.973 1.00 55.55 ? 283 THR A CG2 1 ATOM 2024 N N . SER A 1 248 ? 24.554 74.402 23.291 1.00 43.69 ? 284 SER A N 1 ATOM 2025 C CA . SER A 1 248 ? 24.966 73.015 23.429 1.00 42.34 ? 284 SER A CA 1 ATOM 2026 C C . SER A 1 248 ? 23.764 72.131 23.722 1.00 42.30 ? 284 SER A C 1 ATOM 2027 O O . SER A 1 248 ? 23.066 72.338 24.711 1.00 45.30 ? 284 SER A O 1 ATOM 2028 C CB . SER A 1 248 ? 25.998 72.873 24.553 1.00 42.84 ? 284 SER A CB 1 ATOM 2029 O OG . SER A 1 248 ? 27.157 73.641 24.280 1.00 44.03 ? 284 SER A OG 1 ATOM 2030 N N . ILE A 1 249 ? 23.534 71.141 22.865 1.00 39.72 ? 285 ILE A N 1 ATOM 2031 C CA . ILE A 1 249 ? 22.480 70.161 23.094 1.00 36.97 ? 285 ILE A CA 1 ATOM 2032 C C . ILE A 1 249 ? 22.980 69.004 23.952 1.00 36.53 ? 285 ILE A C 1 ATOM 2033 O O . ILE A 1 249 ? 23.961 68.344 23.606 1.00 36.61 ? 285 ILE A O 1 ATOM 2034 C CB . ILE A 1 249 ? 21.967 69.566 21.771 1.00 39.91 ? 285 ILE A CB 1 ATOM 2035 C CG1 . ILE A 1 249 ? 21.629 70.677 20.774 1.00 43.58 ? 285 ILE A CG1 1 ATOM 2036 C CG2 . ILE A 1 249 ? 20.749 68.697 22.029 1.00 43.00 ? 285 ILE A CG2 1 ATOM 2037 C CD1 . ILE A 1 249 ? 20.395 71.467 21.149 1.00 47.46 ? 285 ILE A CD1 1 ATOM 2038 N N . GLN A 1 250 ? 22.291 68.735 25.054 1.00 40.04 ? 286 GLN A N 1 ATOM 2039 C CA . GLN A 1 250 ? 22.675 67.639 25.931 1.00 35.74 ? 286 GLN A CA 1 ATOM 2040 C C . GLN A 1 250 ? 22.073 66.321 25.470 1.00 35.85 ? 286 GLN A C 1 ATOM 2041 O O . GLN A 1 250 ? 20.907 66.246 25.089 1.00 40.85 ? 286 GLN A O 1 ATOM 2042 C CB . GLN A 1 250 ? 22.252 67.910 27.380 1.00 34.59 ? 286 GLN A CB 1 ATOM 2043 C CG . GLN A 1 250 ? 22.783 66.870 28.377 1.00 32.90 ? 286 GLN A CG 1 ATOM 2044 C CD . GLN A 1 250 ? 22.374 67.144 29.825 1.00 44.86 ? 286 GLN A CD 1 ATOM 2045 O OE1 . GLN A 1 250 ? 21.870 68.223 30.156 1.00 41.79 ? 286 GLN A OE1 1 ATOM 2046 N NE2 . GLN A 1 250 ? 22.588 66.156 30.696 1.00 41.26 ? 286 GLN A NE2 1 ATOM 2047 N N . ILE A 1 251 ? 22.870 65.271 25.517 1.00 31.17 ? 287 ILE A N 1 ATOM 2048 C CA . ILE A 1 251 ? 22.348 63.932 25.311 1.00 33.82 ? 287 ILE A CA 1 ATOM 2049 C C . ILE A 1 251 ? 22.444 63.204 26.636 1.00 34.46 ? 287 ILE A C 1 ATOM 2050 O O . ILE A 1 251 ? 23.529 63.056 27.181 1.00 34.00 ? 287 ILE A O 1 ATOM 2051 C CB . ILE A 1 251 ? 23.164 63.187 24.257 1.00 32.41 ? 287 ILE A CB 1 ATOM 2052 C CG1 . ILE A 1 251 ? 23.031 63.885 22.905 1.00 34.55 ? 287 ILE A CG1 1 ATOM 2053 C CG2 . ILE A 1 251 ? 22.726 61.745 24.169 1.00 38.81 ? 287 ILE A CG2 1 ATOM 2054 C CD1 . ILE A 1 251 ? 23.812 63.194 21.797 1.00 35.94 ? 287 ILE A CD1 1 ATOM 2055 N N . THR A 1 252 ? 21.314 62.763 27.171 1.00 34.40 ? 288 THR A N 1 ATOM 2056 C CA . THR A 1 252 ? 21.310 62.166 28.501 1.00 37.95 ? 288 THR A CA 1 ATOM 2057 C C . THR A 1 252 ? 21.595 60.667 28.439 1.00 37.92 ? 288 THR A C 1 ATOM 2058 O O . THR A 1 252 ? 21.363 60.023 27.418 1.00 42.80 ? 288 THR A O 1 ATOM 2059 C CB . THR A 1 252 ? 19.960 62.421 29.208 1.00 42.74 ? 288 THR A CB 1 ATOM 2060 O OG1 . THR A 1 252 ? 18.911 61.758 28.484 1.00 45.36 ? 288 THR A OG1 1 ATOM 2061 C CG2 . THR A 1 252 ? 19.667 63.919 29.241 1.00 39.44 ? 288 THR A CG2 1 ATOM 2062 N N . ALA A 1 253 ? 22.109 60.111 29.524 1.00 34.57 ? 289 ALA A N 1 ATOM 2063 C CA . ALA A 1 253 ? 22.391 58.688 29.559 1.00 34.38 ? 289 ALA A CA 1 ATOM 2064 C C . ALA A 1 253 ? 21.073 57.946 29.603 1.00 35.17 ? 289 ALA A C 1 ATOM 2065 O O . ALA A 1 253 ? 20.069 58.513 30.023 1.00 34.92 ? 289 ALA A O 1 ATOM 2066 C CB . ALA A 1 253 ? 23.232 58.342 30.775 1.00 31.40 ? 289 ALA A CB 1 ATOM 2067 N N . PRO A 1 254 ? 21.074 56.677 29.170 1.00 33.73 ? 290 PRO A N 1 ATOM 2068 C CA . PRO A 1 254 ? 19.882 55.827 29.221 1.00 38.20 ? 290 PRO A CA 1 ATOM 2069 C C . PRO A 1 254 ? 19.289 55.862 30.619 1.00 37.61 ? 290 PRO A C 1 ATOM 2070 O O . PRO A 1 254 ? 20.003 56.151 31.576 1.00 38.89 ? 290 PRO A O 1 ATOM 2071 C CB . PRO A 1 254 ? 20.439 54.431 28.943 1.00 36.29 ? 290 PRO A CB 1 ATOM 2072 C CG . PRO A 1 254 ? 21.675 54.674 28.138 1.00 36.81 ? 290 PRO A CG 1 ATOM 2073 C CD . PRO A 1 254 ? 22.245 55.966 28.628 1.00 32.18 ? 290 PRO A CD 1 ATOM 2074 N N . ALA A 1 255 ? 18.004 55.564 30.750 1.00 40.47 ? 291 ALA A N 1 ATOM 2075 C CA . ALA A 1 255 ? 17.388 55.544 32.073 1.00 42.19 ? 291 ALA A CA 1 ATOM 2076 C C . ALA A 1 255 ? 17.922 54.381 32.902 1.00 42.32 ? 291 ALA A C 1 ATOM 2077 O O . ALA A 1 255 ? 17.951 54.452 34.134 1.00 44.17 ? 291 ALA A O 1 ATOM 2078 C CB . ALA A 1 255 ? 15.870 55.486 31.965 1.00 48.49 ? 291 ALA A CB 1 ATOM 2079 N N . SER A 1 256 ? 18.358 53.316 32.229 1.00 38.97 ? 292 SER A N 1 ATOM 2080 C CA . SER A 1 256 ? 18.953 52.173 32.930 1.00 42.12 ? 292 SER A CA 1 ATOM 2081 C C . SER A 1 256 ? 20.309 52.521 33.551 1.00 39.24 ? 292 SER A C 1 ATOM 2082 O O . SER A 1 256 ? 20.809 51.796 34.414 1.00 41.63 ? 292 SER A O 1 ATOM 2083 C CB . SER A 1 256 ? 19.104 50.974 31.994 1.00 37.69 ? 292 SER A CB 1 ATOM 2084 O OG . SER A 1 256 ? 19.871 51.326 30.859 1.00 43.25 ? 292 SER A OG 1 ATOM 2085 N N . MET A 1 257 ? 20.908 53.619 33.098 1.00 35.79 ? 293 MET A N 1 ATOM 2086 C CA . MET A 1 257 ? 22.149 54.100 33.695 1.00 38.99 ? 293 MET A CA 1 ATOM 2087 C C . MET A 1 257 ? 21.863 55.131 34.781 1.00 37.46 ? 293 MET A C 1 ATOM 2088 O O . MET A 1 257 ? 22.512 55.133 35.824 1.00 35.44 ? 293 MET A O 1 ATOM 2089 C CB . MET A 1 257 ? 23.071 54.693 32.629 1.00 33.27 ? 293 MET A CB 1 ATOM 2090 C CG . MET A 1 257 ? 23.665 53.645 31.701 1.00 39.02 ? 293 MET A CG 1 ATOM 2091 S SD . MET A 1 257 ? 24.896 52.692 32.591 1.00 37.60 ? 293 MET A SD 1 ATOM 2092 C CE . MET A 1 257 ? 24.941 51.166 31.655 1.00 31.08 ? 293 MET A CE 1 ATOM 2093 N N . LEU A 1 258 ? 20.891 56.000 34.525 1.00 38.69 ? 294 LEU A N 1 ATOM 2094 C CA . LEU A 1 258 ? 20.541 57.081 35.449 1.00 41.58 ? 294 LEU A CA 1 ATOM 2095 C C . LEU A 1 258 ? 20.063 56.639 36.838 1.00 40.70 ? 294 LEU A C 1 ATOM 2096 O O . LEU A 1 258 ? 20.096 57.430 37.782 1.00 40.64 ? 294 LEU A O 1 ATOM 2097 C CB . LEU A 1 258 ? 19.489 57.993 34.825 1.00 39.72 ? 294 LEU A CB 1 ATOM 2098 C CG . LEU A 1 258 ? 19.949 58.811 33.624 1.00 40.44 ? 294 LEU A CG 1 ATOM 2099 C CD1 . LEU A 1 258 ? 18.768 59.539 33.014 1.00 45.31 ? 294 LEU A CD1 1 ATOM 2100 C CD2 . LEU A 1 258 ? 21.025 59.799 34.046 1.00 40.40 ? 294 LEU A CD2 1 ATOM 2101 N N . ILE A 1 259 ? 19.610 55.395 36.966 1.00 41.52 ? 295 ILE A N 1 ATOM 2102 C CA . ILE A 1 259 ? 19.146 54.889 38.260 1.00 42.78 ? 295 ILE A CA 1 ATOM 2103 C C . ILE A 1 259 ? 20.250 54.840 39.323 1.00 44.11 ? 295 ILE A C 1 ATOM 2104 O O . ILE A 1 259 ? 19.947 54.740 40.506 1.00 46.69 ? 295 ILE A O 1 ATOM 2105 C CB . ILE A 1 259 ? 18.535 53.467 38.149 1.00 45.40 ? 295 ILE A CB 1 ATOM 2106 C CG1 . ILE A 1 259 ? 19.613 52.442 37.791 1.00 43.66 ? 295 ILE A CG1 1 ATOM 2107 C CG2 . ILE A 1 259 ? 17.397 53.430 37.123 1.00 47.67 ? 295 ILE A CG2 1 ATOM 2108 C CD1 . ILE A 1 259 ? 19.125 51.005 37.849 1.00 47.03 ? 295 ILE A CD1 1 ATOM 2109 N N . GLY A 1 260 ? 21.518 54.888 38.905 1.00 37.53 ? 296 GLY A N 1 ATOM 2110 C CA . GLY A 1 260 ? 22.646 54.827 39.838 1.00 40.70 ? 296 GLY A CA 1 ATOM 2111 C C . GLY A 1 260 ? 23.929 55.468 39.310 1.00 37.28 ? 296 GLY A C 1 ATOM 2112 O O . GLY A 1 260 ? 23.905 56.110 38.267 1.00 33.47 ? 296 GLY A O 1 ATOM 2113 N N . ASP A 1 261 ? 25.039 55.310 40.035 1.00 33.81 ? 297 ASP A N 1 ATOM 2114 C CA . ASP A 1 261 ? 26.340 55.803 39.572 1.00 32.39 ? 297 ASP A CA 1 ATOM 2115 C C . ASP A 1 261 ? 26.712 55.109 38.258 1.00 31.77 ? 297 ASP A C 1 ATOM 2116 O O . ASP A 1 261 ? 26.505 53.893 38.101 1.00 27.95 ? 297 ASP A O 1 ATOM 2117 C CB . ASP A 1 261 ? 27.447 55.522 40.604 1.00 33.58 ? 297 ASP A CB 1 ATOM 2118 C CG . ASP A 1 261 ? 27.327 56.370 41.872 1.00 39.77 ? 297 ASP A CG 1 ATOM 2119 O OD1 . ASP A 1 261 ? 26.566 57.365 41.881 1.00 41.66 ? 297 ASP A OD1 1 ATOM 2120 O OD2 . ASP A 1 261 ? 28.025 56.042 42.861 1.00 39.06 ? 297 ASP A OD2 1 ATOM 2121 N N . HIS A 1 262 ? 27.284 55.867 37.327 1.00 31.75 ? 298 HIS A N 1 ATOM 2122 C CA . HIS A 1 262 ? 27.676 55.310 36.030 1.00 32.06 ? 298 HIS A CA 1 ATOM 2123 C C . HIS A 1 262 ? 28.853 56.085 35.445 1.00 33.32 ? 298 HIS A C 1 ATOM 2124 O O . HIS A 1 262 ? 29.259 57.123 35.980 1.00 33.18 ? 298 HIS A O 1 ATOM 2125 C CB . HIS A 1 262 ? 26.490 55.367 35.054 1.00 29.96 ? 298 HIS A CB 1 ATOM 2126 C CG . HIS A 1 262 ? 25.946 56.749 34.860 1.00 30.52 ? 298 HIS A CG 1 ATOM 2127 N ND1 . HIS A 1 262 ? 25.028 57.317 35.716 1.00 34.85 ? 298 HIS A ND1 1 ATOM 2128 C CD2 . HIS A 1 262 ? 26.219 57.691 33.927 1.00 27.64 ? 298 HIS A CD2 1 ATOM 2129 C CE1 . HIS A 1 262 ? 24.748 58.544 35.310 1.00 32.09 ? 298 HIS A CE1 1 ATOM 2130 N NE2 . HIS A 1 262 ? 25.459 58.795 34.226 1.00 28.40 ? 298 HIS A NE2 1 ATOM 2131 N N . TYR A 1 263 ? 29.384 55.584 34.335 1.00 28.50 ? 299 TYR A N 1 ATOM 2132 C CA . TYR A 1 263 ? 30.465 56.249 33.629 1.00 29.36 ? 299 TYR A CA 1 ATOM 2133 C C . TYR A 1 263 ? 30.101 56.374 32.158 1.00 30.41 ? 299 TYR A C 1 ATOM 2134 O O . TYR A 1 263 ? 29.408 55.516 31.621 1.00 28.52 ? 299 TYR A O 1 ATOM 2135 C CB . TYR A 1 263 ? 31.740 55.409 33.691 1.00 26.03 ? 299 TYR A CB 1 ATOM 2136 C CG . TYR A 1 263 ? 32.208 54.987 35.061 1.00 27.35 ? 299 TYR A CG 1 ATOM 2137 C CD1 . TYR A 1 263 ? 32.750 55.904 35.949 1.00 29.04 ? 299 TYR A CD1 1 ATOM 2138 C CD2 . TYR A 1 263 ? 32.153 53.663 35.447 1.00 28.01 ? 299 TYR A CD2 1 ATOM 2139 C CE1 . TYR A 1 263 ? 33.194 55.514 37.206 1.00 24.24 ? 299 TYR A CE1 1 ATOM 2140 C CE2 . TYR A 1 263 ? 32.598 53.258 36.696 1.00 28.05 ? 299 TYR A CE2 1 ATOM 2141 C CZ . TYR A 1 263 ? 33.119 54.187 37.569 1.00 27.06 ? 299 TYR A CZ 1 ATOM 2142 O OH . TYR A 1 263 ? 33.566 53.768 38.804 1.00 26.99 ? 299 TYR A OH 1 ATOM 2143 N N . LEU A 1 264 ? 30.580 57.431 31.508 1.00 29.64 ? 300 LEU A N 1 ATOM 2144 C CA . LEU A 1 264 ? 30.623 57.472 30.047 1.00 28.98 ? 300 LEU A CA 1 ATOM 2145 C C . LEU A 1 264 ? 31.947 56.827 29.628 1.00 32.65 ? 300 LEU A C 1 ATOM 2146 O O . LEU A 1 264 ? 33.006 57.317 30.011 1.00 30.86 ? 300 LEU A O 1 ATOM 2147 C CB . LEU A 1 264 ? 30.575 58.915 29.536 1.00 28.78 ? 300 LEU A CB 1 ATOM 2148 C CG . LEU A 1 264 ? 30.835 59.060 28.033 1.00 29.28 ? 300 LEU A CG 1 ATOM 2149 C CD1 . LEU A 1 264 ? 29.656 58.510 27.244 1.00 27.64 ? 300 LEU A CD1 1 ATOM 2150 C CD2 . LEU A 1 264 ? 31.072 60.493 27.668 1.00 31.73 ? 300 LEU A CD2 1 ATOM 2151 N N . CYS A 1 265 ? 31.918 55.739 28.860 1.00 28.25 ? 301 CYS A N 1 ATOM 2152 C CA . CYS A 1 265 ? 33.167 55.000 28.641 1.00 33.70 ? 301 CYS A CA 1 ATOM 2153 C C . CYS A 1 265 ? 33.693 54.955 27.200 1.00 35.30 ? 301 CYS A C 1 ATOM 2154 O O . CYS A 1 265 ? 34.835 54.547 26.965 1.00 34.39 ? 301 CYS A O 1 ATOM 2155 C CB . CYS A 1 265 ? 33.100 53.593 29.251 1.00 34.37 ? 301 CYS A CB 1 ATOM 2156 S SG . CYS A 1 265 ? 31.809 52.563 28.552 1.00 46.02 ? 301 CYS A SG 1 ATOM 2157 N N . ASP A 1 266 ? 32.888 55.395 26.241 1.00 32.30 ? 302 ASP A N 1 ATOM 2158 C CA . ASP A 1 266 ? 33.333 55.432 24.849 1.00 32.96 ? 302 ASP A CA 1 ATOM 2159 C C . ASP A 1 266 ? 32.421 56.318 24.010 1.00 32.96 ? 302 ASP A C 1 ATOM 2160 O O . ASP A 1 266 ? 31.198 56.311 24.180 1.00 32.85 ? 302 ASP A O 1 ATOM 2161 C CB . ASP A 1 266 ? 33.406 54.028 24.243 1.00 33.74 ? 302 ASP A CB 1 ATOM 2162 C CG . ASP A 1 266 ? 33.928 54.039 22.802 1.00 40.28 ? 302 ASP A CG 1 ATOM 2163 O OD1 . ASP A 1 266 ? 35.146 53.840 22.603 1.00 43.00 ? 302 ASP A OD1 1 ATOM 2164 O OD2 . ASP A 1 266 ? 33.122 54.268 21.866 1.00 42.17 ? 302 ASP A OD2 1 ATOM 2165 N N . VAL A 1 267 ? 33.034 57.109 23.139 1.00 25.75 ? 303 VAL A N 1 ATOM 2166 C CA . VAL A 1 267 ? 32.304 57.979 22.230 1.00 30.66 ? 303 VAL A CA 1 ATOM 2167 C C . VAL A 1 267 ? 32.817 57.719 20.809 1.00 32.26 ? 303 VAL A C 1 ATOM 2168 O O . VAL A 1 267 ? 34.003 57.877 20.531 1.00 29.94 ? 303 VAL A O 1 ATOM 2169 C CB . VAL A 1 267 ? 32.472 59.469 22.608 1.00 30.53 ? 303 VAL A CB 1 ATOM 2170 C CG1 . VAL A 1 267 ? 31.670 60.351 21.671 1.00 30.11 ? 303 VAL A CG1 1 ATOM 2171 C CG2 . VAL A 1 267 ? 32.036 59.710 24.058 1.00 31.38 ? 303 VAL A CG2 1 ATOM 2172 N N . THR A 1 268 ? 31.941 57.284 19.912 1.00 30.86 ? 304 THR A N 1 ATOM 2173 C CA . THR A 1 268 ? 32.367 57.063 18.532 1.00 32.83 ? 304 THR A CA 1 ATOM 2174 C C . THR A 1 268 ? 31.384 57.655 17.527 1.00 30.81 ? 304 THR A C 1 ATOM 2175 O O . THR A 1 268 ? 30.206 57.320 17.548 1.00 33.41 ? 304 THR A O 1 ATOM 2176 C CB . THR A 1 268 ? 32.581 55.563 18.243 1.00 29.85 ? 304 THR A CB 1 ATOM 2177 O OG1 . THR A 1 268 ? 33.510 55.031 19.196 1.00 34.86 ? 304 THR A OG1 1 ATOM 2178 C CG2 . THR A 1 268 ? 33.153 55.363 16.823 1.00 28.40 ? 304 THR A CG2 1 ATOM 2179 N N . TRP A 1 269 ? 31.860 58.555 16.673 1.00 27.69 ? 305 TRP A N 1 ATOM 2180 C CA . TRP A 1 269 ? 31.036 59.073 15.581 1.00 30.56 ? 305 TRP A CA 1 ATOM 2181 C C . TRP A 1 269 ? 30.859 57.995 14.520 1.00 33.14 ? 305 TRP A C 1 ATOM 2182 O O . TRP A 1 269 ? 31.842 57.503 13.969 1.00 34.14 ? 305 TRP A O 1 ATOM 2183 C CB . TRP A 1 269 ? 31.679 60.310 14.956 1.00 29.52 ? 305 TRP A CB 1 ATOM 2184 C CG . TRP A 1 269 ? 31.423 61.573 15.733 1.00 32.57 ? 305 TRP A CG 1 ATOM 2185 C CD1 . TRP A 1 269 ? 32.267 62.183 16.626 1.00 31.60 ? 305 TRP A CD1 1 ATOM 2186 C CD2 . TRP A 1 269 ? 30.233 62.371 15.698 1.00 34.35 ? 305 TRP A CD2 1 ATOM 2187 N NE1 . TRP A 1 269 ? 31.672 63.315 17.138 1.00 29.36 ? 305 TRP A NE1 1 ATOM 2188 C CE2 . TRP A 1 269 ? 30.425 63.451 16.587 1.00 31.38 ? 305 TRP A CE2 1 ATOM 2189 C CE3 . TRP A 1 269 ? 29.028 62.285 14.992 1.00 33.37 ? 305 TRP A CE3 1 ATOM 2190 C CZ2 . TRP A 1 269 ? 29.458 64.433 16.787 1.00 32.30 ? 305 TRP A CZ2 1 ATOM 2191 C CZ3 . TRP A 1 269 ? 28.060 63.266 15.200 1.00 33.82 ? 305 TRP A CZ3 1 ATOM 2192 C CH2 . TRP A 1 269 ? 28.284 64.322 16.087 1.00 34.10 ? 305 TRP A CH2 1 ATOM 2193 N N . ALA A 1 270 ? 29.615 57.620 14.236 1.00 31.64 ? 306 ALA A N 1 ATOM 2194 C CA . ALA A 1 270 ? 29.352 56.625 13.198 1.00 31.72 ? 306 ALA A CA 1 ATOM 2195 C C . ALA A 1 270 ? 29.238 57.262 11.818 1.00 34.29 ? 306 ALA A C 1 ATOM 2196 O O . ALA A 1 270 ? 29.785 56.740 10.850 1.00 37.73 ? 306 ALA A O 1 ATOM 2197 C CB . ALA A 1 270 ? 28.099 55.834 13.529 1.00 32.16 ? 306 ALA A CB 1 ATOM 2198 N N . THR A 1 271 ? 28.529 58.385 11.728 1.00 29.83 ? 307 THR A N 1 ATOM 2199 C CA . THR A 1 271 ? 28.408 59.133 10.477 1.00 34.73 ? 307 THR A CA 1 ATOM 2200 C C . THR A 1 271 ? 28.455 60.633 10.742 1.00 38.63 ? 307 THR A C 1 ATOM 2201 O O . THR A 1 271 ? 28.939 61.071 11.782 1.00 39.88 ? 307 THR A O 1 ATOM 2202 C CB . THR A 1 271 ? 27.080 58.832 9.750 1.00 34.83 ? 307 THR A CB 1 ATOM 2203 O OG1 . THR A 1 271 ? 25.987 59.318 10.537 1.00 36.90 ? 307 THR A OG1 1 ATOM 2204 C CG2 . THR A 1 271 ? 26.910 57.339 9.518 1.00 34.02 ? 307 THR A CG2 1 ATOM 2205 N N . GLN A 1 272 ? 27.940 61.424 9.804 1.00 38.53 ? 308 GLN A N 1 ATOM 2206 C CA . GLN A 1 272 ? 27.911 62.870 9.971 1.00 34.08 ? 308 GLN A CA 1 ATOM 2207 C C . GLN A 1 272 ? 26.831 63.259 10.967 1.00 36.03 ? 308 GLN A C 1 ATOM 2208 O O . GLN A 1 272 ? 26.875 64.345 11.538 1.00 41.82 ? 308 GLN A O 1 ATOM 2209 C CB . GLN A 1 272 ? 27.644 63.576 8.631 1.00 44.97 ? 308 GLN A CB 1 ATOM 2210 C CG . GLN A 1 272 ? 28.645 63.258 7.515 1.00 46.16 ? 308 GLN A CG 1 ATOM 2211 C CD . GLN A 1 272 ? 30.055 63.687 7.866 1.00 48.29 ? 308 GLN A CD 1 ATOM 2212 O OE1 . GLN A 1 272 ? 30.285 64.289 8.924 1.00 48.08 ? 308 GLN A OE1 1 ATOM 2213 N NE2 . GLN A 1 272 ? 31.014 63.371 6.990 1.00 43.18 ? 308 GLN A NE2 1 ATOM 2214 N N . GLU A 1 273 ? 25.863 62.372 11.177 1.00 35.16 ? 309 GLU A N 1 ATOM 2215 C CA . GLU A 1 273 ? 24.675 62.707 11.960 1.00 36.62 ? 309 GLU A CA 1 ATOM 2216 C C . GLU A 1 273 ? 24.301 61.618 12.949 1.00 36.06 ? 309 GLU A C 1 ATOM 2217 O O . GLU A 1 273 ? 23.184 61.607 13.475 1.00 39.10 ? 309 GLU A O 1 ATOM 2218 C CB . GLU A 1 273 ? 23.474 62.966 11.033 1.00 42.34 ? 309 GLU A CB 1 ATOM 2219 C CG . GLU A 1 273 ? 23.672 64.126 10.054 1.00 44.83 ? 309 GLU A CG 1 ATOM 2220 C CD . GLU A 1 273 ? 22.544 64.248 9.031 1.00 55.29 ? 309 GLU A CD 1 ATOM 2221 O OE1 . GLU A 1 273 ? 21.466 63.639 9.233 1.00 51.73 ? 309 GLU A OE1 1 ATOM 2222 O OE2 . GLU A 1 273 ? 22.743 64.959 8.019 1.00 59.14 ? 309 GLU A OE2 1 ATOM 2223 N N . ARG A 1 274 ? 25.225 60.691 13.189 1.00 35.62 ? 310 ARG A N 1 ATOM 2224 C CA . ARG A 1 274 ? 24.990 59.600 14.139 1.00 32.46 ? 310 ARG A CA 1 ATOM 2225 C C . ARG A 1 274 ? 26.191 59.417 15.064 1.00 33.33 ? 310 ARG A C 1 ATOM 2226 O O . ARG A 1 274 ? 27.311 59.171 14.597 1.00 33.74 ? 310 ARG A O 1 ATOM 2227 C CB . ARG A 1 274 ? 24.697 58.297 13.392 1.00 34.62 ? 310 ARG A CB 1 ATOM 2228 C CG . ARG A 1 274 ? 24.604 57.060 14.271 1.00 30.03 ? 310 ARG A CG 1 ATOM 2229 C CD . ARG A 1 274 ? 24.074 55.872 13.451 1.00 37.59 ? 310 ARG A CD 1 ATOM 2230 N NE . ARG A 1 274 ? 22.627 55.970 13.249 1.00 38.95 ? 310 ARG A NE 1 ATOM 2231 C CZ . ARG A 1 274 ? 21.908 55.142 12.494 1.00 42.41 ? 310 ARG A CZ 1 ATOM 2232 N NH1 . ARG A 1 274 ? 22.499 54.147 11.848 1.00 40.06 ? 310 ARG A NH1 1 ATOM 2233 N NH2 . ARG A 1 274 ? 20.594 55.310 12.380 1.00 42.46 ? 310 ARG A NH2 1 ATOM 2234 N N . ILE A 1 275 ? 25.958 59.571 16.366 1.00 33.41 ? 311 ILE A N 1 ATOM 2235 C CA . ILE A 1 275 ? 26.991 59.344 17.375 1.00 35.05 ? 311 ILE A CA 1 ATOM 2236 C C . ILE A 1 275 ? 26.651 58.104 18.164 1.00 30.99 ? 311 ILE A C 1 ATOM 2237 O O . ILE A 1 275 ? 25.499 57.902 18.538 1.00 35.62 ? 311 ILE A O 1 ATOM 2238 C CB . ILE A 1 275 ? 27.075 60.484 18.419 1.00 37.94 ? 311 ILE A CB 1 ATOM 2239 C CG1 . ILE A 1 275 ? 26.844 61.842 17.779 1.00 40.13 ? 311 ILE A CG1 1 ATOM 2240 C CG2 . ILE A 1 275 ? 28.426 60.480 19.140 1.00 34.38 ? 311 ILE A CG2 1 ATOM 2241 C CD1 . ILE A 1 275 ? 27.048 63.001 18.746 1.00 43.13 ? 311 ILE A CD1 1 ATOM 2242 N N . SER A 1 276 ? 27.669 57.299 18.443 1.00 32.60 ? 312 SER A N 1 ATOM 2243 C CA . SER A 1 276 ? 27.551 56.145 19.326 1.00 33.45 ? 312 SER A CA 1 ATOM 2244 C C . SER A 1 276 ? 28.146 56.477 20.703 1.00 33.29 ? 312 SER A C 1 ATOM 2245 O O . SER A 1 276 ? 29.243 57.032 20.779 1.00 32.87 ? 312 SER A O 1 ATOM 2246 C CB . SER A 1 276 ? 28.311 54.973 18.711 1.00 30.14 ? 312 SER A CB 1 ATOM 2247 O OG . SER A 1 276 ? 28.258 53.855 19.550 1.00 35.83 ? 312 SER A OG 1 ATOM 2248 N N . LEU A 1 277 ? 27.421 56.147 21.775 1.00 35.60 ? 313 LEU A N 1 ATOM 2249 C CA . LEU A 1 277 ? 27.846 56.412 23.151 1.00 29.89 ? 313 LEU A CA 1 ATOM 2250 C C . LEU A 1 277 ? 27.740 55.122 23.943 1.00 33.19 ? 313 LEU A C 1 ATOM 2251 O O . LEU A 1 277 ? 26.693 54.481 23.940 1.00 35.90 ? 313 LEU A O 1 ATOM 2252 C CB . LEU A 1 277 ? 26.928 57.439 23.818 1.00 28.86 ? 313 LEU A CB 1 ATOM 2253 C CG . LEU A 1 277 ? 26.799 58.808 23.171 1.00 36.19 ? 313 LEU A CG 1 ATOM 2254 C CD1 . LEU A 1 277 ? 25.893 59.671 24.008 1.00 37.10 ? 313 LEU A CD1 1 ATOM 2255 C CD2 . LEU A 1 277 ? 28.166 59.446 23.052 1.00 36.72 ? 313 LEU A CD2 1 ATOM 2256 N N . GLN A 1 278 ? 28.809 54.735 24.628 1.00 31.74 ? 314 GLN A N 1 ATOM 2257 C CA . GLN A 1 278 ? 28.740 53.583 25.518 1.00 32.75 ? 314 GLN A CA 1 ATOM 2258 C C . GLN A 1 278 ? 28.844 54.030 26.959 1.00 32.02 ? 314 GLN A C 1 ATOM 2259 O O . GLN A 1 278 ? 29.728 54.802 27.308 1.00 30.18 ? 314 GLN A O 1 ATOM 2260 C CB . GLN A 1 278 ? 29.831 52.558 25.207 1.00 33.58 ? 314 GLN A CB 1 ATOM 2261 C CG . GLN A 1 278 ? 29.424 51.556 24.147 1.00 40.26 ? 314 GLN A CG 1 ATOM 2262 C CD . GLN A 1 278 ? 30.573 50.674 23.724 1.00 38.84 ? 314 GLN A CD 1 ATOM 2263 O OE1 . GLN A 1 278 ? 30.638 49.501 24.095 1.00 43.59 ? 314 GLN A OE1 1 ATOM 2264 N NE2 . GLN A 1 278 ? 31.498 51.239 22.952 1.00 37.96 ? 314 GLN A NE2 1 ATOM 2265 N N . TRP A 1 279 ? 27.925 53.534 27.779 1.00 31.35 ? 315 TRP A N 1 ATOM 2266 C CA . TRP A 1 279 ? 27.851 53.867 29.189 1.00 30.27 ? 315 TRP A CA 1 ATOM 2267 C C . TRP A 1 279 ? 28.066 52.575 29.963 1.00 32.02 ? 315 TRP A C 1 ATOM 2268 O O . TRP A 1 279 ? 27.760 51.487 29.466 1.00 31.06 ? 315 TRP A O 1 ATOM 2269 C CB . TRP A 1 279 ? 26.476 54.430 29.527 1.00 28.69 ? 315 TRP A CB 1 ATOM 2270 C CG . TRP A 1 279 ? 26.075 55.631 28.750 1.00 26.66 ? 315 TRP A CG 1 ATOM 2271 C CD1 . TRP A 1 279 ? 25.453 55.647 27.533 1.00 31.60 ? 315 TRP A CD1 1 ATOM 2272 C CD2 . TRP A 1 279 ? 26.236 57.002 29.135 1.00 26.59 ? 315 TRP A CD2 1 ATOM 2273 N NE1 . TRP A 1 279 ? 25.226 56.948 27.136 1.00 28.85 ? 315 TRP A NE1 1 ATOM 2274 C CE2 . TRP A 1 279 ? 25.695 57.795 28.102 1.00 28.51 ? 315 TRP A CE2 1 ATOM 2275 C CE3 . TRP A 1 279 ? 26.800 57.638 30.244 1.00 28.45 ? 315 TRP A CE3 1 ATOM 2276 C CZ2 . TRP A 1 279 ? 25.707 59.182 28.143 1.00 31.92 ? 315 TRP A CZ2 1 ATOM 2277 C CZ3 . TRP A 1 279 ? 26.802 59.022 30.284 1.00 31.10 ? 315 TRP A CZ3 1 ATOM 2278 C CH2 . TRP A 1 279 ? 26.258 59.776 29.243 1.00 30.02 ? 315 TRP A CH2 1 ATOM 2279 N N . LEU A 1 280 ? 28.588 52.692 31.176 1.00 28.17 ? 316 LEU A N 1 ATOM 2280 C CA . LEU A 1 280 ? 28.928 51.529 31.992 1.00 30.76 ? 316 LEU A CA 1 ATOM 2281 C C . LEU A 1 280 ? 28.468 51.787 33.424 1.00 30.26 ? 316 LEU A C 1 ATOM 2282 O O . LEU A 1 280 ? 28.716 52.862 33.963 1.00 31.29 ? 316 LEU A O 1 ATOM 2283 C CB . LEU A 1 280 ? 30.447 51.311 31.948 1.00 27.32 ? 316 LEU A CB 1 ATOM 2284 C CG . LEU A 1 280 ? 31.087 50.201 32.789 1.00 31.76 ? 316 LEU A CG 1 ATOM 2285 C CD1 . LEU A 1 280 ? 30.657 48.828 32.320 1.00 33.32 ? 316 LEU A CD1 1 ATOM 2286 C CD2 . LEU A 1 280 ? 32.614 50.320 32.763 1.00 31.21 ? 316 LEU A CD2 1 ATOM 2287 N N . ARG A 1 281 ? 27.782 50.830 34.043 1.00 29.35 ? 317 ARG A N 1 ATOM 2288 C CA . ARG A 1 281 ? 27.371 51.022 35.434 1.00 32.56 ? 317 ARG A CA 1 ATOM 2289 C C . ARG A 1 281 ? 28.572 51.033 36.369 1.00 32.17 ? 317 ARG A C 1 ATOM 2290 O O . ARG A 1 281 ? 29.599 50.435 36.066 1.00 28.06 ? 317 ARG A O 1 ATOM 2291 C CB . ARG A 1 281 ? 26.410 49.929 35.886 1.00 35.38 ? 317 ARG A CB 1 ATOM 2292 C CG . ARG A 1 281 ? 24.983 50.180 35.501 1.00 37.13 ? 317 ARG A CG 1 ATOM 2293 C CD . ARG A 1 281 ? 24.075 49.157 36.151 1.00 41.15 ? 317 ARG A CD 1 ATOM 2294 N NE . ARG A 1 281 ? 22.697 49.349 35.719 1.00 48.31 ? 317 ARG A NE 1 ATOM 2295 C CZ . ARG A 1 281 ? 21.799 48.375 35.628 1.00 49.43 ? 317 ARG A CZ 1 ATOM 2296 N NH1 . ARG A 1 281 ? 22.132 47.128 35.954 1.00 43.47 ? 317 ARG A NH1 1 ATOM 2297 N NH2 . ARG A 1 281 ? 20.568 48.656 35.218 1.00 49.63 ? 317 ARG A NH2 1 ATOM 2298 N N . ARG A 1 282 ? 28.442 51.673 37.527 1.00 30.22 ? 318 ARG A N 1 ATOM 2299 C CA . ARG A 1 282 ? 29.564 51.676 38.468 1.00 30.36 ? 318 ARG A CA 1 ATOM 2300 C C . ARG A 1 282 ? 29.954 50.259 38.871 1.00 30.95 ? 318 ARG A C 1 ATOM 2301 O O . ARG A 1 282 ? 31.124 49.963 39.071 1.00 31.74 ? 318 ARG A O 1 ATOM 2302 C CB . ARG A 1 282 ? 29.292 52.533 39.697 1.00 31.44 ? 318 ARG A CB 1 ATOM 2303 C CG . ARG A 1 282 ? 30.455 52.494 40.676 1.00 31.18 ? 318 ARG A CG 1 ATOM 2304 C CD . ARG A 1 282 ? 30.398 53.633 41.671 1.00 30.57 ? 318 ARG A CD 1 ATOM 2305 N NE . ARG A 1 282 ? 31.599 53.653 42.496 1.00 25.65 ? 318 ARG A NE 1 ATOM 2306 C CZ . ARG A 1 282 ? 31.864 54.578 43.414 1.00 33.90 ? 318 ARG A CZ 1 ATOM 2307 N NH1 . ARG A 1 282 ? 31.017 55.584 43.632 1.00 31.58 ? 318 ARG A NH1 1 ATOM 2308 N NH2 . ARG A 1 282 ? 32.986 54.498 44.116 1.00 29.07 ? 318 ARG A NH2 1 ATOM 2309 N N . ILE A 1 283 ? 28.968 49.381 38.977 1.00 32.77 ? 319 ILE A N 1 ATOM 2310 C CA . ILE A 1 283 ? 29.234 47.951 39.075 1.00 33.34 ? 319 ILE A CA 1 ATOM 2311 C C . ILE A 1 283 ? 29.469 47.483 37.641 1.00 36.84 ? 319 ILE A C 1 ATOM 2312 O O . ILE A 1 283 ? 28.523 47.349 36.856 1.00 36.69 ? 319 ILE A O 1 ATOM 2313 C CB . ILE A 1 283 ? 28.021 47.211 39.634 1.00 36.72 ? 319 ILE A CB 1 ATOM 2314 C CG1 . ILE A 1 283 ? 27.340 48.058 40.725 1.00 44.57 ? 319 ILE A CG1 1 ATOM 2315 C CG2 . ILE A 1 283 ? 28.409 45.798 40.068 1.00 37.28 ? 319 ILE A CG2 1 ATOM 2316 C CD1 . ILE A 1 283 ? 26.442 49.229 40.148 1.00 43.93 ? 319 ILE A CD1 1 ATOM 2317 N N . GLN A 1 284 ? 30.725 47.251 37.287 1.00 33.15 ? 320 GLN A N 1 ATOM 2318 C CA . GLN A 1 284 ? 31.101 47.207 35.876 1.00 33.27 ? 320 GLN A CA 1 ATOM 2319 C C . GLN A 1 284 ? 30.797 45.898 35.126 1.00 35.03 ? 320 GLN A C 1 ATOM 2320 O O . GLN A 1 284 ? 31.636 45.378 34.375 1.00 33.47 ? 320 GLN A O 1 ATOM 2321 C CB . GLN A 1 284 ? 32.565 47.599 35.732 1.00 31.86 ? 320 GLN A CB 1 ATOM 2322 C CG . GLN A 1 284 ? 32.823 49.039 36.180 1.00 30.93 ? 320 GLN A CG 1 ATOM 2323 C CD . GLN A 1 284 ? 34.290 49.398 36.119 1.00 31.42 ? 320 GLN A CD 1 ATOM 2324 O OE1 . GLN A 1 284 ? 34.964 49.124 35.122 1.00 31.58 ? 320 GLN A OE1 1 ATOM 2325 N NE2 . GLN A 1 284 ? 34.800 49.999 37.189 1.00 27.31 ? 320 GLN A NE2 1 ATOM 2326 N N . ASN A 1 285 ? 29.592 45.375 35.320 1.00 35.41 ? 321 ASN A N 1 ATOM 2327 C CA . ASN A 1 285 ? 29.179 44.175 34.595 1.00 34.23 ? 321 ASN A CA 1 ATOM 2328 C C . ASN A 1 285 ? 27.960 44.448 33.738 1.00 37.35 ? 321 ASN A C 1 ATOM 2329 O O . ASN A 1 285 ? 27.323 43.525 33.231 1.00 38.20 ? 321 ASN A O 1 ATOM 2330 C CB . ASN A 1 285 ? 28.927 42.993 35.547 1.00 37.27 ? 321 ASN A CB 1 ATOM 2331 C CG . ASN A 1 285 ? 27.840 43.276 36.563 1.00 35.67 ? 321 ASN A CG 1 ATOM 2332 O OD1 . ASN A 1 285 ? 27.101 44.259 36.447 1.00 37.28 ? 321 ASN A OD1 1 ATOM 2333 N ND2 . ASN A 1 285 ? 27.734 42.413 37.572 1.00 42.81 ? 321 ASN A ND2 1 ATOM 2334 N N . TYR A 1 286 ? 27.645 45.726 33.575 1.00 35.16 ? 322 TYR A N 1 ATOM 2335 C CA . TYR A 1 286 ? 26.503 46.118 32.782 1.00 34.49 ? 322 TYR A CA 1 ATOM 2336 C C . TYR A 1 286 ? 26.808 47.388 31.999 1.00 34.87 ? 322 TYR A C 1 ATOM 2337 O O . TYR A 1 286 ? 27.060 48.429 32.593 1.00 32.54 ? 322 TYR A O 1 ATOM 2338 C CB . TYR A 1 286 ? 25.293 46.326 33.687 1.00 37.51 ? 322 TYR A CB 1 ATOM 2339 C CG . TYR A 1 286 ? 23.986 46.437 32.933 1.00 43.17 ? 322 TYR A CG 1 ATOM 2340 C CD1 . TYR A 1 286 ? 23.496 47.675 32.530 1.00 40.89 ? 322 TYR A CD1 1 ATOM 2341 C CD2 . TYR A 1 286 ? 23.243 45.302 32.625 1.00 46.70 ? 322 TYR A CD2 1 ATOM 2342 C CE1 . TYR A 1 286 ? 22.302 47.782 31.844 1.00 41.21 ? 322 TYR A CE1 1 ATOM 2343 C CE2 . TYR A 1 286 ? 22.055 45.396 31.935 1.00 49.12 ? 322 TYR A CE2 1 ATOM 2344 C CZ . TYR A 1 286 ? 21.589 46.638 31.545 1.00 47.68 ? 322 TYR A CZ 1 ATOM 2345 O OH . TYR A 1 286 ? 20.404 46.731 30.854 1.00 53.46 ? 322 TYR A OH 1 ATOM 2346 N N . SER A 1 287 ? 26.788 47.297 30.666 1.00 33.34 ? 323 SER A N 1 ATOM 2347 C CA . SER A 1 287 ? 27.001 48.461 29.808 1.00 33.46 ? 323 SER A CA 1 ATOM 2348 C C . SER A 1 287 ? 25.918 48.583 28.741 1.00 35.65 ? 323 SER A C 1 ATOM 2349 O O . SER A 1 287 ? 25.300 47.595 28.344 1.00 36.98 ? 323 SER A O 1 ATOM 2350 C CB . SER A 1 287 ? 28.379 48.419 29.133 1.00 34.66 ? 323 SER A CB 1 ATOM 2351 O OG . SER A 1 287 ? 28.406 47.497 28.056 1.00 41.96 ? 323 SER A OG 1 ATOM 2352 N N . VAL A 1 288 ? 25.701 49.807 28.280 1.00 33.79 ? 324 VAL A N 1 ATOM 2353 C CA . VAL A 1 288 ? 24.681 50.090 27.288 1.00 34.02 ? 324 VAL A CA 1 ATOM 2354 C C . VAL A 1 288 ? 25.262 50.984 26.209 1.00 36.64 ? 324 VAL A C 1 ATOM 2355 O O . VAL A 1 288 ? 25.870 52.010 26.508 1.00 33.97 ? 324 VAL A O 1 ATOM 2356 C CB . VAL A 1 288 ? 23.466 50.810 27.914 1.00 35.06 ? 324 VAL A CB 1 ATOM 2357 C CG1 . VAL A 1 288 ? 22.497 51.264 26.834 1.00 33.60 ? 324 VAL A CG1 1 ATOM 2358 C CG2 . VAL A 1 288 ? 22.766 49.908 28.930 1.00 34.25 ? 324 VAL A CG2 1 ATOM 2359 N N . MET A 1 289 ? 25.073 50.584 24.955 1.00 33.66 ? 325 MET A N 1 ATOM 2360 C CA . MET A 1 289 ? 25.438 51.409 23.822 1.00 37.22 ? 325 MET A CA 1 ATOM 2361 C C . MET A 1 289 ? 24.195 52.101 23.294 1.00 37.11 ? 325 MET A C 1 ATOM 2362 O O . MET A 1 289 ? 23.205 51.445 22.976 1.00 40.09 ? 325 MET A O 1 ATOM 2363 C CB . MET A 1 289 ? 26.056 50.552 22.720 1.00 39.11 ? 325 MET A CB 1 ATOM 2364 C CG . MET A 1 289 ? 26.895 51.333 21.720 1.00 42.20 ? 325 MET A CG 1 ATOM 2365 S SD . MET A 1 289 ? 27.610 50.278 20.431 1.00 45.13 ? 325 MET A SD 1 ATOM 2366 C CE . MET A 1 289 ? 26.291 50.348 19.243 1.00 42.42 ? 325 MET A CE 1 ATOM 2367 N N . ASP A 1 290 ? 24.261 53.426 23.204 1.00 34.11 ? 326 ASP A N 1 ATOM 2368 C CA . ASP A 1 290 ? 23.200 54.250 22.645 1.00 36.45 ? 326 ASP A CA 1 ATOM 2369 C C . ASP A 1 290 ? 23.587 54.651 21.225 1.00 40.52 ? 326 ASP A C 1 ATOM 2370 O O . ASP A 1 290 ? 24.750 54.945 20.969 1.00 39.09 ? 326 ASP A O 1 ATOM 2371 C CB . ASP A 1 290 ? 23.067 55.524 23.478 1.00 36.90 ? 326 ASP A CB 1 ATOM 2372 C CG . ASP A 1 290 ? 21.761 55.605 24.213 1.00 47.22 ? 326 ASP A CG 1 ATOM 2373 O OD1 . ASP A 1 290 ? 20.851 54.807 23.888 1.00 49.38 ? 326 ASP A OD1 1 ATOM 2374 O OD2 . ASP A 1 290 ? 21.642 56.479 25.106 1.00 47.77 ? 326 ASP A OD2 1 ATOM 2375 N N . ILE A 1 291 ? 22.626 54.665 20.304 1.00 39.63 ? 327 ILE A N 1 ATOM 2376 C CA . ILE A 1 291 ? 22.861 55.163 18.950 1.00 38.05 ? 327 ILE A CA 1 ATOM 2377 C C . ILE A 1 291 ? 22.071 56.449 18.766 1.00 37.52 ? 327 ILE A C 1 ATOM 2378 O O . ILE A 1 291 ? 20.848 56.415 18.706 1.00 45.59 ? 327 ILE A O 1 ATOM 2379 C CB . ILE A 1 291 ? 22.378 54.167 17.874 1.00 40.51 ? 327 ILE A CB 1 ATOM 2380 C CG1 . ILE A 1 291 ? 23.048 52.803 18.036 1.00 37.07 ? 327 ILE A CG1 1 ATOM 2381 C CG2 . ILE A 1 291 ? 22.618 54.732 16.493 1.00 37.08 ? 327 ILE A CG2 1 ATOM 2382 C CD1 . ILE A 1 291 ? 24.506 52.813 17.769 1.00 38.59 ? 327 ILE A CD1 1 ATOM 2383 N N . CYS A 1 292 ? 22.753 57.579 18.664 1.00 38.19 ? 328 CYS A N 1 ATOM 2384 C CA . CYS A 1 292 ? 22.072 58.873 18.710 1.00 40.61 ? 328 CYS A CA 1 ATOM 2385 C C . CYS A 1 292 ? 22.078 59.611 17.388 1.00 40.17 ? 328 CYS A C 1 ATOM 2386 O O . CYS A 1 292 ? 23.141 59.887 16.835 1.00 41.61 ? 328 CYS A O 1 ATOM 2387 C CB . CYS A 1 292 ? 22.697 59.758 19.790 1.00 41.97 ? 328 CYS A CB 1 ATOM 2388 S SG . CYS A 1 292 ? 22.547 59.047 21.442 1.00 53.30 ? 328 CYS A SG 1 ATOM 2389 N N . ASP A 1 293 ? 20.888 59.958 16.901 1.00 43.34 ? 329 ASP A N 1 ATOM 2390 C CA . ASP A 1 293 ? 20.740 60.569 15.581 1.00 42.84 ? 329 ASP A CA 1 ATOM 2391 C C . ASP A 1 293 ? 20.321 62.035 15.613 1.00 42.60 ? 329 ASP A C 1 ATOM 2392 O O . ASP A 1 293 ? 19.497 62.449 16.424 1.00 44.13 ? 329 ASP A O 1 ATOM 2393 C CB . ASP A 1 293 ? 19.742 59.780 14.737 1.00 44.75 ? 329 ASP A CB 1 ATOM 2394 C CG . ASP A 1 293 ? 20.297 58.457 14.273 1.00 43.32 ? 329 ASP A CG 1 ATOM 2395 O OD1 . ASP A 1 293 ? 21.517 58.381 14.015 1.00 44.56 ? 329 ASP A OD1 1 ATOM 2396 O OD2 . ASP A 1 293 ? 19.512 57.494 14.160 1.00 50.07 ? 329 ASP A OD2 1 ATOM 2397 N N . TYR A 1 294 ? 20.894 62.806 14.703 1.00 37.81 ? 330 TYR A N 1 ATOM 2398 C CA . TYR A 1 294 ? 20.570 64.212 14.579 1.00 42.23 ? 330 TYR A CA 1 ATOM 2399 C C . TYR A 1 294 ? 19.272 64.405 13.797 1.00 49.69 ? 330 TYR A C 1 ATOM 2400 O O . TYR A 1 294 ? 19.020 63.722 12.804 1.00 46.14 ? 330 TYR A O 1 ATOM 2401 C CB . TYR A 1 294 ? 21.717 64.937 13.888 1.00 43.05 ? 330 TYR A CB 1 ATOM 2402 C CG . TYR A 1 294 ? 21.491 66.414 13.675 1.00 47.46 ? 330 TYR A CG 1 ATOM 2403 C CD1 . TYR A 1 294 ? 21.498 67.296 14.749 1.00 47.78 ? 330 TYR A CD1 1 ATOM 2404 C CD2 . TYR A 1 294 ? 21.294 66.930 12.399 1.00 48.62 ? 330 TYR A CD2 1 ATOM 2405 C CE1 . TYR A 1 294 ? 21.300 68.644 14.563 1.00 49.20 ? 330 TYR A CE1 1 ATOM 2406 C CE2 . TYR A 1 294 ? 21.101 68.282 12.200 1.00 51.24 ? 330 TYR A CE2 1 ATOM 2407 C CZ . TYR A 1 294 ? 21.105 69.134 13.286 1.00 55.15 ? 330 TYR A CZ 1 ATOM 2408 O OH . TYR A 1 294 ? 20.915 70.482 13.107 1.00 55.07 ? 330 TYR A OH 1 ATOM 2409 N N . ASP A 1 295 ? 18.454 65.338 14.262 1.00 52.47 ? 331 ASP A N 1 ATOM 2410 C CA . ASP A 1 295 ? 17.186 65.660 13.623 1.00 53.40 ? 331 ASP A CA 1 ATOM 2411 C C . ASP A 1 295 ? 17.283 67.064 13.018 1.00 55.40 ? 331 ASP A C 1 ATOM 2412 O O . ASP A 1 295 ? 17.210 68.060 13.737 1.00 57.35 ? 331 ASP A O 1 ATOM 2413 C CB . ASP A 1 295 ? 16.065 65.591 14.668 1.00 54.21 ? 331 ASP A CB 1 ATOM 2414 C CG . ASP A 1 295 ? 14.677 65.769 14.067 1.00 59.80 ? 331 ASP A CG 1 ATOM 2415 O OD1 . ASP A 1 295 ? 14.556 66.398 12.990 1.00 58.65 ? 331 ASP A OD1 1 ATOM 2416 O OD2 . ASP A 1 295 ? 13.703 65.281 14.685 1.00 56.61 ? 331 ASP A OD2 1 ATOM 2417 N N . GLU A 1 296 ? 17.471 67.143 11.702 1.00 57.27 ? 332 GLU A N 1 ATOM 2418 C CA . GLU A 1 296 ? 17.579 68.433 11.016 1.00 60.20 ? 332 GLU A CA 1 ATOM 2419 C C . GLU A 1 296 ? 16.502 69.441 11.446 1.00 62.96 ? 332 GLU A C 1 ATOM 2420 O O . GLU A 1 296 ? 16.787 70.628 11.625 1.00 61.63 ? 332 GLU A O 1 ATOM 2421 C CB . GLU A 1 296 ? 17.531 68.244 9.496 1.00 60.09 ? 332 GLU A CB 1 ATOM 2422 C CG . GLU A 1 296 ? 18.822 67.720 8.886 1.00 64.79 ? 332 GLU A CG 1 ATOM 2423 N N . SER A 1 297 ? 15.272 68.961 11.617 1.00 62.03 ? 333 SER A N 1 ATOM 2424 C CA . SER A 1 297 ? 14.130 69.840 11.878 1.00 63.75 ? 333 SER A CA 1 ATOM 2425 C C . SER A 1 297 ? 14.164 70.506 13.256 1.00 64.05 ? 333 SER A C 1 ATOM 2426 O O . SER A 1 297 ? 13.917 71.708 13.369 1.00 68.94 ? 333 SER A O 1 ATOM 2427 C CB . SER A 1 297 ? 12.803 69.088 11.682 1.00 65.03 ? 333 SER A CB 1 ATOM 2428 O OG . SER A 1 297 ? 12.444 68.333 12.831 1.00 65.89 ? 333 SER A OG 1 ATOM 2429 N N . SER A 1 298 ? 14.461 69.731 14.296 1.00 59.42 ? 334 SER A N 1 ATOM 2430 C CA . SER A 1 298 ? 14.470 70.263 15.658 1.00 60.81 ? 334 SER A CA 1 ATOM 2431 C C . SER A 1 298 ? 15.864 70.675 16.140 1.00 62.79 ? 334 SER A C 1 ATOM 2432 O O . SER A 1 298 ? 15.998 71.423 17.106 1.00 62.07 ? 334 SER A O 1 ATOM 2433 C CB . SER A 1 298 ? 13.839 69.267 16.642 1.00 63.21 ? 334 SER A CB 1 ATOM 2434 O OG . SER A 1 298 ? 14.545 68.036 16.677 1.00 66.08 ? 334 SER A OG 1 ATOM 2435 N N . GLY A 1 299 ? 16.903 70.194 15.466 1.00 62.10 ? 335 GLY A N 1 ATOM 2436 C CA . GLY A 1 299 ? 18.263 70.454 15.904 1.00 57.40 ? 335 GLY A CA 1 ATOM 2437 C C . GLY A 1 299 ? 18.616 69.661 17.152 1.00 58.44 ? 335 GLY A C 1 ATOM 2438 O O . GLY A 1 299 ? 19.646 69.905 17.779 1.00 56.87 ? 335 GLY A O 1 ATOM 2439 N N . ARG A 1 300 ? 17.757 68.710 17.514 1.00 56.22 ? 336 ARG A N 1 ATOM 2440 C CA . ARG A 1 300 ? 17.983 67.866 18.684 1.00 55.14 ? 336 ARG A CA 1 ATOM 2441 C C . ARG A 1 300 ? 18.683 66.564 18.288 1.00 53.21 ? 336 ARG A C 1 ATOM 2442 O O . ARG A 1 300 ? 18.747 66.216 17.112 1.00 50.34 ? 336 ARG A O 1 ATOM 2443 C CB . ARG A 1 300 ? 16.654 67.542 19.382 1.00 60.25 ? 336 ARG A CB 1 ATOM 2444 C CG . ARG A 1 300 ? 15.763 68.754 19.669 1.00 66.45 ? 336 ARG A CG 1 ATOM 2445 C CD . ARG A 1 300 ? 16.294 69.589 20.833 1.00 68.99 ? 336 ARG A CD 1 ATOM 2446 N NE . ARG A 1 300 ? 16.168 71.029 20.586 1.00 74.18 ? 336 ARG A NE 1 ATOM 2447 C CZ . ARG A 1 300 ? 16.554 71.974 21.442 1.00 78.23 ? 336 ARG A CZ 1 ATOM 2448 N NH1 . ARG A 1 300 ? 17.089 71.632 22.610 1.00 72.25 ? 336 ARG A NH1 1 ATOM 2449 N NH2 . ARG A 1 300 ? 16.407 73.259 21.136 1.00 73.22 ? 336 ARG A NH2 1 ATOM 2450 N N . TRP A 1 301 ? 19.207 65.849 19.276 1.00 50.04 ? 337 TRP A N 1 ATOM 2451 C CA . TRP A 1 301 ? 19.752 64.521 19.038 1.00 46.93 ? 337 TRP A CA 1 ATOM 2452 C C . TRP A 1 301 ? 18.827 63.524 19.698 1.00 48.79 ? 337 TRP A C 1 ATOM 2453 O O . TRP A 1 301 ? 18.473 63.686 20.856 1.00 54.43 ? 337 TRP A O 1 ATOM 2454 C CB . TRP A 1 301 ? 21.175 64.404 19.595 1.00 42.10 ? 337 TRP A CB 1 ATOM 2455 C CG . TRP A 1 301 ? 22.133 65.256 18.847 1.00 38.87 ? 337 TRP A CG 1 ATOM 2456 C CD1 . TRP A 1 301 ? 22.344 66.588 19.021 1.00 40.08 ? 337 TRP A CD1 1 ATOM 2457 C CD2 . TRP A 1 301 ? 22.986 64.850 17.769 1.00 37.40 ? 337 TRP A CD2 1 ATOM 2458 N NE1 . TRP A 1 301 ? 23.282 67.036 18.131 1.00 41.42 ? 337 TRP A NE1 1 ATOM 2459 C CE2 . TRP A 1 301 ? 23.693 65.987 17.349 1.00 37.62 ? 337 TRP A CE2 1 ATOM 2460 C CE3 . TRP A 1 301 ? 23.218 63.633 17.118 1.00 38.67 ? 337 TRP A CE3 1 ATOM 2461 C CZ2 . TRP A 1 301 ? 24.623 65.946 16.307 1.00 39.32 ? 337 TRP A CZ2 1 ATOM 2462 C CZ3 . TRP A 1 301 ? 24.143 63.594 16.088 1.00 37.85 ? 337 TRP A CZ3 1 ATOM 2463 C CH2 . TRP A 1 301 ? 24.833 64.741 15.693 1.00 35.02 ? 337 TRP A CH2 1 ATOM 2464 N N . ASN A 1 302 ? 18.411 62.506 18.958 1.00 49.68 ? 338 ASN A N 1 ATOM 2465 C CA . ASN A 1 302 ? 17.458 61.540 19.494 1.00 48.23 ? 338 ASN A CA 1 ATOM 2466 C C . ASN A 1 302 ? 18.047 60.147 19.582 1.00 47.68 ? 338 ASN A C 1 ATOM 2467 O O . ASN A 1 302 ? 18.653 59.659 18.628 1.00 46.28 ? 338 ASN A O 1 ATOM 2468 C CB . ASN A 1 302 ? 16.168 61.524 18.667 1.00 52.41 ? 338 ASN A CB 1 ATOM 2469 C CG . ASN A 1 302 ? 15.439 62.859 18.700 1.00 58.03 ? 338 ASN A CG 1 ATOM 2470 O OD1 . ASN A 1 302 ? 15.029 63.329 19.768 1.00 64.28 ? 338 ASN A OD1 1 ATOM 2471 N ND2 . ASN A 1 302 ? 15.267 63.475 17.529 1.00 56.80 ? 338 ASN A ND2 1 ATOM 2472 N N . CYS A 1 303 ? 17.863 59.515 20.736 1.00 48.52 ? 339 CYS A N 1 ATOM 2473 C CA . CYS A 1 303 ? 18.400 58.192 20.993 1.00 48.45 ? 339 CYS A CA 1 ATOM 2474 C C . CYS A 1 303 ? 17.253 57.229 21.220 1.00 52.89 ? 339 CYS A C 1 ATOM 2475 O O . CYS A 1 303 ? 16.795 57.078 22.349 1.00 56.93 ? 339 CYS A O 1 ATOM 2476 C CB . CYS A 1 303 ? 19.283 58.215 22.246 1.00 49.64 ? 339 CYS A CB 1 ATOM 2477 S SG . CYS A 1 303 ? 20.665 59.383 22.195 1.00 59.09 ? 339 CYS A SG 1 ATOM 2478 N N . LEU A 1 304 ? 16.783 56.581 20.162 1.00 50.92 ? 340 LEU A N 1 ATOM 2479 C CA . LEU A 1 304 ? 15.695 55.622 20.310 1.00 50.80 ? 340 LEU A CA 1 ATOM 2480 C C . LEU A 1 304 ? 16.027 54.574 21.361 1.00 49.33 ? 340 LEU A C 1 ATOM 2481 O O . LEU A 1 304 ? 17.016 53.857 21.237 1.00 49.55 ? 340 LEU A O 1 ATOM 2482 C CB . LEU A 1 304 ? 15.377 54.939 18.982 1.00 51.27 ? 340 LEU A CB 1 ATOM 2483 C CG . LEU A 1 304 ? 14.526 55.745 18.004 1.00 57.38 ? 340 LEU A CG 1 ATOM 2484 C CD1 . LEU A 1 304 ? 13.511 56.580 18.784 1.00 54.88 ? 340 LEU A CD1 1 ATOM 2485 C CD2 . LEU A 1 304 ? 15.393 56.628 17.113 1.00 58.54 ? 340 LEU A CD2 1 ATOM 2486 N N . VAL A 1 305 ? 15.196 54.482 22.395 1.00 49.54 ? 341 VAL A N 1 ATOM 2487 C CA . VAL A 1 305 ? 15.425 53.506 23.459 1.00 54.42 ? 341 VAL A CA 1 ATOM 2488 C C . VAL A 1 305 ? 15.489 52.101 22.876 1.00 50.61 ? 341 VAL A C 1 ATOM 2489 O O . VAL A 1 305 ? 16.156 51.213 23.413 1.00 51.29 ? 341 VAL A O 1 ATOM 2490 C CB . VAL A 1 305 ? 14.320 53.553 24.555 1.00 53.66 ? 341 VAL A CB 1 ATOM 2491 C CG1 . VAL A 1 305 ? 14.599 52.517 25.636 1.00 49.96 ? 341 VAL A CG1 1 ATOM 2492 C CG2 . VAL A 1 305 ? 14.219 54.954 25.170 1.00 55.52 ? 341 VAL A CG2 1 ATOM 2493 N N . ALA A 1 306 ? 14.800 51.918 21.759 1.00 48.42 ? 342 ALA A N 1 ATOM 2494 C CA . ALA A 1 306 ? 14.620 50.602 21.166 1.00 50.28 ? 342 ALA A CA 1 ATOM 2495 C C . ALA A 1 306 ? 15.888 50.031 20.530 1.00 50.64 ? 342 ALA A C 1 ATOM 2496 O O . ALA A 1 306 ? 16.043 48.812 20.445 1.00 52.09 ? 342 ALA A O 1 ATOM 2497 C CB . ALA A 1 306 ? 13.477 50.644 20.148 1.00 48.09 ? 342 ALA A CB 1 ATOM 2498 N N . ARG A 1 307 ? 16.791 50.897 20.078 1.00 50.65 ? 343 ARG A N 1 ATOM 2499 C CA . ARG A 1 307 ? 17.995 50.420 19.385 1.00 50.21 ? 343 ARG A CA 1 ATOM 2500 C C . ARG A 1 307 ? 19.258 50.435 20.247 1.00 50.17 ? 343 ARG A C 1 ATOM 2501 O O . ARG A 1 307 ? 20.369 50.374 19.723 1.00 47.50 ? 343 ARG A O 1 ATOM 2502 C CB . ARG A 1 307 ? 18.245 51.203 18.099 1.00 49.29 ? 343 ARG A CB 1 ATOM 2503 C CG . ARG A 1 307 ? 18.387 52.692 18.314 1.00 54.52 ? 343 ARG A CG 1 ATOM 2504 C CD . ARG A 1 307 ? 18.998 53.361 17.087 1.00 50.13 ? 343 ARG A CD 1 ATOM 2505 N NE . ARG A 1 307 ? 18.309 52.998 15.857 1.00 48.19 ? 343 ARG A NE 1 ATOM 2506 C CZ . ARG A 1 307 ? 17.825 53.879 14.988 1.00 54.03 ? 343 ARG A CZ 1 ATOM 2507 N NH1 . ARG A 1 307 ? 17.953 55.180 15.213 1.00 52.59 ? 343 ARG A NH1 1 ATOM 2508 N NH2 . ARG A 1 307 ? 17.214 53.460 13.887 1.00 57.51 ? 343 ARG A NH2 1 ATOM 2509 N N . GLN A 1 308 ? 19.089 50.509 21.564 1.00 51.39 ? 344 GLN A N 1 ATOM 2510 C CA . GLN A 1 308 ? 20.211 50.332 22.474 1.00 47.84 ? 344 GLN A CA 1 ATOM 2511 C C . GLN A 1 308 ? 20.750 48.915 22.353 1.00 48.73 ? 344 GLN A C 1 ATOM 2512 O O . GLN A 1 308 ? 19.987 47.976 22.133 1.00 51.62 ? 344 GLN A O 1 ATOM 2513 C CB . GLN A 1 308 ? 19.780 50.584 23.917 1.00 43.80 ? 344 GLN A CB 1 ATOM 2514 C CG . GLN A 1 308 ? 19.370 52.018 24.212 1.00 48.48 ? 344 GLN A CG 1 ATOM 2515 C CD . GLN A 1 308 ? 18.782 52.158 25.596 1.00 47.27 ? 344 GLN A CD 1 ATOM 2516 O OE1 . GLN A 1 308 ? 18.647 51.172 26.324 1.00 44.93 ? 344 GLN A OE1 1 ATOM 2517 N NE2 . GLN A 1 308 ? 18.414 53.381 25.966 1.00 49.10 ? 344 GLN A NE2 1 ATOM 2518 N N . HIS A 1 309 ? 22.064 48.761 22.490 1.00 44.32 ? 345 HIS A N 1 ATOM 2519 C CA . HIS A 1 309 ? 22.661 47.438 22.591 1.00 42.40 ? 345 HIS A CA 1 ATOM 2520 C C . HIS A 1 309 ? 23.186 47.237 24.008 1.00 45.51 ? 345 HIS A C 1 ATOM 2521 O O . HIS A 1 309 ? 23.930 48.071 24.529 1.00 41.99 ? 345 HIS A O 1 ATOM 2522 C CB . HIS A 1 309 ? 23.791 47.253 21.571 1.00 46.41 ? 345 HIS A CB 1 ATOM 2523 C CG . HIS A 1 309 ? 24.741 46.143 21.919 1.00 55.22 ? 345 HIS A CG 1 ATOM 2524 N ND1 . HIS A 1 309 ? 26.115 46.290 21.873 1.00 54.30 ? 345 HIS A ND1 1 ATOM 2525 C CD2 . HIS A 1 309 ? 24.514 44.872 22.337 1.00 52.68 ? 345 HIS A CD2 1 ATOM 2526 C CE1 . HIS A 1 309 ? 26.691 45.158 22.245 1.00 51.56 ? 345 HIS A CE1 1 ATOM 2527 N NE2 . HIS A 1 309 ? 25.742 44.281 22.530 1.00 53.82 ? 345 HIS A NE2 1 ATOM 2528 N N . ILE A 1 310 ? 22.796 46.133 24.633 1.00 46.16 ? 346 ILE A N 1 ATOM 2529 C CA . ILE A 1 310 ? 23.176 45.873 26.015 1.00 44.95 ? 346 ILE A CA 1 ATOM 2530 C C . ILE A 1 310 ? 24.247 44.794 26.119 1.00 46.14 ? 346 ILE A C 1 ATOM 2531 O O . ILE A 1 310 ? 24.212 43.800 25.396 1.00 41.40 ? 346 ILE A O 1 ATOM 2532 C CB . ILE A 1 310 ? 21.964 45.443 26.855 1.00 46.11 ? 346 ILE A CB 1 ATOM 2533 C CG1 . ILE A 1 310 ? 20.914 46.553 26.883 1.00 51.21 ? 346 ILE A CG1 1 ATOM 2534 C CG2 . ILE A 1 310 ? 22.396 45.078 28.268 1.00 44.57 ? 346 ILE A CG2 1 ATOM 2535 C CD1 . ILE A 1 310 ? 19.752 46.255 27.820 1.00 56.58 ? 346 ILE A CD1 1 ATOM 2536 N N . GLU A 1 311 ? 25.194 44.989 27.031 1.00 38.25 ? 347 GLU A N 1 ATOM 2537 C CA . GLU A 1 311 ? 26.245 44.010 27.245 1.00 39.10 ? 347 GLU A CA 1 ATOM 2538 C C . GLU A 1 311 ? 26.389 43.711 28.720 1.00 42.80 ? 347 GLU A C 1 ATOM 2539 O O . GLU A 1 311 ? 26.439 44.628 29.537 1.00 43.13 ? 347 GLU A O 1 ATOM 2540 C CB . GLU A 1 311 ? 27.565 44.538 26.706 1.00 44.47 ? 347 GLU A CB 1 ATOM 2541 C CG . GLU A 1 311 ? 28.089 43.769 25.526 1.00 50.63 ? 347 GLU A CG 1 ATOM 2542 C CD . GLU A 1 311 ? 29.606 43.773 25.471 1.00 53.29 ? 347 GLU A CD 1 ATOM 2543 O OE1 . GLU A 1 311 ? 30.214 42.783 25.962 1.00 48.76 ? 347 GLU A OE1 1 ATOM 2544 O OE2 . GLU A 1 311 ? 30.177 44.763 24.942 1.00 49.05 ? 347 GLU A OE2 1 ATOM 2545 N N . MET A 1 312 ? 26.462 42.427 29.062 1.00 43.59 ? 348 MET A N 1 ATOM 2546 C CA . MET A 1 312 ? 26.561 42.003 30.457 1.00 43.14 ? 348 MET A CA 1 ATOM 2547 C C . MET A 1 312 ? 27.611 40.919 30.603 1.00 44.36 ? 348 MET A C 1 ATOM 2548 O O . MET A 1 312 ? 27.966 40.248 29.636 1.00 45.86 ? 348 MET A O 1 ATOM 2549 C CB . MET A 1 312 ? 25.213 41.461 30.952 1.00 44.35 ? 348 MET A CB 1 ATOM 2550 C CG . MET A 1 312 ? 24.049 42.411 30.749 1.00 48.05 ? 348 MET A CG 1 ATOM 2551 S SD . MET A 1 312 ? 22.425 41.654 31.000 1.00 70.95 ? 348 MET A SD 1 ATOM 2552 C CE . MET A 1 312 ? 22.459 41.325 32.757 1.00 47.08 ? 348 MET A CE 1 ATOM 2553 N N . SER A 1 313 ? 28.107 40.742 31.820 1.00 43.94 ? 349 SER A N 1 ATOM 2554 C CA . SER A 1 313 ? 28.979 39.616 32.118 1.00 47.34 ? 349 SER A CA 1 ATOM 2555 C C . SER A 1 313 ? 28.535 39.008 33.436 1.00 49.80 ? 349 SER A C 1 ATOM 2556 O O . SER A 1 313 ? 28.129 39.732 34.350 1.00 50.53 ? 349 SER A O 1 ATOM 2557 C CB . SER A 1 313 ? 30.440 40.066 32.204 1.00 47.09 ? 349 SER A CB 1 ATOM 2558 O OG . SER A 1 313 ? 31.304 38.970 32.491 1.00 48.45 ? 349 SER A OG 1 ATOM 2559 N N . THR A 1 314 ? 28.598 37.683 33.542 1.00 54.47 ? 350 THR A N 1 ATOM 2560 C CA . THR A 1 314 ? 28.253 37.018 34.804 1.00 52.23 ? 350 THR A CA 1 ATOM 2561 C C . THR A 1 314 ? 29.493 36.544 35.539 1.00 50.24 ? 350 THR A C 1 ATOM 2562 O O . THR A 1 314 ? 29.485 36.388 36.761 1.00 57.63 ? 350 THR A O 1 ATOM 2563 C CB . THR A 1 314 ? 27.336 35.799 34.588 1.00 58.80 ? 350 THR A CB 1 ATOM 2564 O OG1 . THR A 1 314 ? 27.377 35.395 33.210 1.00 58.89 ? 350 THR A OG1 1 ATOM 2565 C CG2 . THR A 1 314 ? 25.904 36.130 34.996 1.00 59.72 ? 350 THR A CG2 1 ATOM 2566 N N . THR A 1 315 ? 30.560 36.303 34.791 1.00 51.87 ? 351 THR A N 1 ATOM 2567 C CA . THR A 1 315 ? 31.780 35.771 35.381 1.00 48.12 ? 351 THR A CA 1 ATOM 2568 C C . THR A 1 315 ? 32.772 36.872 35.741 1.00 41.41 ? 351 THR A C 1 ATOM 2569 O O . THR A 1 315 ? 33.710 36.640 36.495 1.00 36.60 ? 351 THR A O 1 ATOM 2570 C CB . THR A 1 315 ? 32.459 34.768 34.445 1.00 41.06 ? 351 THR A CB 1 ATOM 2571 O OG1 . THR A 1 315 ? 32.554 35.337 33.136 1.00 44.86 ? 351 THR A OG1 1 ATOM 2572 C CG2 . THR A 1 315 ? 31.651 33.482 34.369 1.00 50.77 ? 351 THR A CG2 1 ATOM 2573 N N . GLY A 1 316 ? 32.572 38.071 35.206 1.00 41.18 ? 352 GLY A N 1 ATOM 2574 C CA . GLY A 1 316 ? 33.497 39.153 35.488 1.00 35.59 ? 352 GLY A CA 1 ATOM 2575 C C . GLY A 1 316 ? 32.976 40.524 35.127 1.00 34.56 ? 352 GLY A C 1 ATOM 2576 O O . GLY A 1 316 ? 31.808 40.845 35.362 1.00 35.72 ? 352 GLY A O 1 ATOM 2577 N N . TRP A 1 317 ? 33.866 41.342 34.572 1.00 30.29 ? 353 TRP A N 1 ATOM 2578 C CA . TRP A 1 317 ? 33.552 42.726 34.223 1.00 32.17 ? 353 TRP A CA 1 ATOM 2579 C C . TRP A 1 317 ? 33.316 42.747 32.720 1.00 30.97 ? 353 TRP A C 1 ATOM 2580 O O . TRP A 1 317 ? 33.490 41.717 32.061 1.00 31.39 ? 353 TRP A O 1 ATOM 2581 C CB . TRP A 1 317 ? 34.716 43.661 34.623 1.00 29.46 ? 353 TRP A CB 1 ATOM 2582 C CG . TRP A 1 317 ? 36.076 43.193 34.145 1.00 25.06 ? 353 TRP A CG 1 ATOM 2583 C CD1 . TRP A 1 317 ? 36.763 43.660 33.069 1.00 26.90 ? 353 TRP A CD1 1 ATOM 2584 C CD2 . TRP A 1 317 ? 36.898 42.155 34.724 1.00 26.82 ? 353 TRP A CD2 1 ATOM 2585 N NE1 . TRP A 1 317 ? 37.954 42.980 32.931 1.00 26.70 ? 353 TRP A NE1 1 ATOM 2586 C CE2 . TRP A 1 317 ? 38.058 42.052 33.935 1.00 27.40 ? 353 TRP A CE2 1 ATOM 2587 C CE3 . TRP A 1 317 ? 36.761 41.309 35.830 1.00 28.27 ? 353 TRP A CE3 1 ATOM 2588 C CZ2 . TRP A 1 317 ? 39.078 41.148 34.218 1.00 25.41 ? 353 TRP A CZ2 1 ATOM 2589 C CZ3 . TRP A 1 317 ? 37.771 40.402 36.107 1.00 26.59 ? 353 TRP A CZ3 1 ATOM 2590 C CH2 . TRP A 1 317 ? 38.918 40.328 35.298 1.00 26.46 ? 353 TRP A CH2 1 ATOM 2591 N N . VAL A 1 318 ? 32.924 43.892 32.168 1.00 30.00 ? 354 VAL A N 1 ATOM 2592 C CA . VAL A 1 318 ? 32.740 43.992 30.713 1.00 31.28 ? 354 VAL A CA 1 ATOM 2593 C C . VAL A 1 318 ? 33.997 44.488 29.979 1.00 32.94 ? 354 VAL A C 1 ATOM 2594 O O . VAL A 1 318 ? 34.536 45.538 30.306 1.00 29.89 ? 354 VAL A O 1 ATOM 2595 C CB . VAL A 1 318 ? 31.539 44.886 30.354 1.00 33.32 ? 354 VAL A CB 1 ATOM 2596 C CG1 . VAL A 1 318 ? 31.423 45.044 28.849 1.00 33.35 ? 354 VAL A CG1 1 ATOM 2597 C CG2 . VAL A 1 318 ? 30.256 44.285 30.909 1.00 36.97 ? 354 VAL A CG2 1 ATOM 2598 N N . GLY A 1 319 ? 34.459 43.731 28.986 1.00 32.40 ? 355 GLY A N 1 ATOM 2599 C CA . GLY A 1 319 ? 35.642 44.105 28.214 1.00 29.67 ? 355 GLY A CA 1 ATOM 2600 C C . GLY A 1 319 ? 36.944 43.722 28.907 1.00 31.30 ? 355 GLY A C 1 ATOM 2601 O O . GLY A 1 319 ? 36.927 43.306 30.065 1.00 29.51 ? 355 GLY A O 1 ATOM 2602 N N . ARG A 1 320 ? 38.077 43.838 28.222 1.00 27.89 ? 356 ARG A N 1 ATOM 2603 C CA . ARG A 1 320 ? 39.336 43.488 28.876 1.00 28.88 ? 356 ARG A CA 1 ATOM 2604 C C . ARG A 1 320 ? 39.628 44.466 29.996 1.00 28.54 ? 356 ARG A C 1 ATOM 2605 O O . ARG A 1 320 ? 40.040 44.061 31.085 1.00 29.27 ? 356 ARG A O 1 ATOM 2606 C CB . ARG A 1 320 ? 40.497 43.444 27.886 1.00 24.95 ? 356 ARG A CB 1 ATOM 2607 C CG . ARG A 1 320 ? 40.404 42.276 26.907 1.00 29.53 ? 356 ARG A CG 1 ATOM 2608 C CD . ARG A 1 320 ? 41.623 42.188 26.011 1.00 28.09 ? 356 ARG A CD 1 ATOM 2609 N NE . ARG A 1 320 ? 41.641 40.905 25.321 1.00 28.90 ? 356 ARG A NE 1 ATOM 2610 C CZ . ARG A 1 320 ? 41.457 40.751 24.012 1.00 30.05 ? 356 ARG A CZ 1 ATOM 2611 N NH1 . ARG A 1 320 ? 41.252 41.808 23.229 1.00 25.84 ? 356 ARG A NH1 1 ATOM 2612 N NH2 . ARG A 1 320 ? 41.482 39.531 23.491 1.00 28.20 ? 356 ARG A NH2 1 ATOM 2613 N N . PHE A 1 321 ? 39.431 45.750 29.705 1.00 28.82 ? 357 PHE A N 1 ATOM 2614 C CA . PHE A 1 321 ? 39.574 46.820 30.685 1.00 29.91 ? 357 PHE A CA 1 ATOM 2615 C C . PHE A 1 321 ? 38.340 47.712 30.668 1.00 34.65 ? 357 PHE A C 1 ATOM 2616 O O . PHE A 1 321 ? 38.092 48.474 31.610 1.00 34.70 ? 357 PHE A O 1 ATOM 2617 C CB . PHE A 1 321 ? 40.812 47.668 30.393 1.00 30.61 ? 357 PHE A CB 1 ATOM 2618 C CG . PHE A 1 321 ? 42.103 46.946 30.623 1.00 32.84 ? 357 PHE A CG 1 ATOM 2619 C CD1 . PHE A 1 321 ? 42.695 46.215 29.605 1.00 31.28 ? 357 PHE A CD1 1 ATOM 2620 C CD2 . PHE A 1 321 ? 42.717 46.985 31.862 1.00 28.52 ? 357 PHE A CD2 1 ATOM 2621 C CE1 . PHE A 1 321 ? 43.888 45.545 29.826 1.00 33.55 ? 357 PHE A CE1 1 ATOM 2622 C CE2 . PHE A 1 321 ? 43.902 46.324 32.086 1.00 30.66 ? 357 PHE A CE2 1 ATOM 2623 C CZ . PHE A 1 321 ? 44.490 45.601 31.074 1.00 35.50 ? 357 PHE A CZ 1 ATOM 2624 N N . ARG A 1 322 ? 37.577 47.623 29.584 1.00 31.61 ? 358 ARG A N 1 ATOM 2625 C CA . ARG A 1 322 ? 36.384 48.444 29.394 1.00 31.48 ? 358 ARG A CA 1 ATOM 2626 C C . ARG A 1 322 ? 35.632 47.924 28.182 1.00 34.84 ? 358 ARG A C 1 ATOM 2627 O O . ARG A 1 322 ? 36.201 47.172 27.383 1.00 28.84 ? 358 ARG A O 1 ATOM 2628 C CB . ARG A 1 322 ? 36.756 49.914 29.180 1.00 33.01 ? 358 ARG A CB 1 ATOM 2629 C CG . ARG A 1 322 ? 37.523 50.178 27.896 1.00 34.34 ? 358 ARG A CG 1 ATOM 2630 C CD . ARG A 1 322 ? 38.037 51.610 27.817 1.00 41.05 ? 358 ARG A CD 1 ATOM 2631 N NE . ARG A 1 322 ? 39.418 51.724 28.301 1.00 47.86 ? 358 ARG A NE 1 ATOM 2632 C CZ . ARG A 1 322 ? 39.746 51.760 29.587 1.00 42.59 ? 358 ARG A CZ 1 ATOM 2633 N NH1 . ARG A 1 322 ? 38.797 51.665 30.494 1.00 45.32 ? 358 ARG A NH1 1 ATOM 2634 N NH2 . ARG A 1 322 ? 41.012 51.867 29.975 1.00 47.67 ? 358 ARG A NH2 1 ATOM 2635 N N . PRO A 1 323 ? 34.353 48.311 28.040 1.00 31.25 ? 359 PRO A N 1 ATOM 2636 C CA . PRO A 1 323 ? 33.609 47.865 26.858 1.00 31.04 ? 359 PRO A CA 1 ATOM 2637 C C . PRO A 1 323 ? 34.398 48.199 25.589 1.00 33.24 ? 359 PRO A C 1 ATOM 2638 O O . PRO A 1 323 ? 35.011 49.259 25.519 1.00 32.88 ? 359 PRO A O 1 ATOM 2639 C CB . PRO A 1 323 ? 32.316 48.688 26.925 1.00 32.17 ? 359 PRO A CB 1 ATOM 2640 C CG . PRO A 1 323 ? 32.143 49.009 28.387 1.00 35.05 ? 359 PRO A CG 1 ATOM 2641 C CD . PRO A 1 323 ? 33.530 49.134 28.951 1.00 31.80 ? 359 PRO A CD 1 ATOM 2642 N N . SER A 1 324 ? 34.375 47.309 24.603 1.00 31.13 ? 360 SER A N 1 ATOM 2643 C CA . SER A 1 324 ? 35.189 47.467 23.403 1.00 29.82 ? 360 SER A CA 1 ATOM 2644 C C . SER A 1 324 ? 34.677 48.558 22.450 1.00 30.28 ? 360 SER A C 1 ATOM 2645 O O . SER A 1 324 ? 33.527 48.983 22.543 1.00 28.40 ? 360 SER A O 1 ATOM 2646 C CB . SER A 1 324 ? 35.272 46.132 22.675 1.00 33.01 ? 360 SER A CB 1 ATOM 2647 O OG . SER A 1 324 ? 33.968 45.655 22.385 1.00 31.55 ? 360 SER A OG 1 ATOM 2648 N N . GLU A 1 325 ? 35.553 49.010 21.551 1.00 26.12 ? 361 GLU A N 1 ATOM 2649 C CA . GLU A 1 325 ? 35.226 50.039 20.573 1.00 30.94 ? 361 GLU A CA 1 ATOM 2650 C C . GLU A 1 325 ? 34.410 49.454 19.418 1.00 31.47 ? 361 GLU A C 1 ATOM 2651 O O . GLU A 1 325 ? 34.748 48.379 18.900 1.00 27.41 ? 361 GLU A O 1 ATOM 2652 C CB . GLU A 1 325 ? 36.514 50.662 20.029 1.00 35.03 ? 361 GLU A CB 1 ATOM 2653 C CG . GLU A 1 325 ? 36.312 51.731 18.955 1.00 36.91 ? 361 GLU A CG 1 ATOM 2654 C CD . GLU A 1 325 ? 37.616 52.118 18.249 1.00 47.41 ? 361 GLU A CD 1 ATOM 2655 O OE1 . GLU A 1 325 ? 38.703 51.735 18.738 1.00 48.69 ? 361 GLU A OE1 1 ATOM 2656 O OE2 . GLU A 1 325 ? 37.555 52.792 17.192 1.00 52.72 ? 361 GLU A OE2 1 ATOM 2657 N N . PRO A 1 326 ? 33.334 50.156 19.009 1.00 30.97 ? 362 PRO A N 1 ATOM 2658 C CA . PRO A 1 326 ? 32.605 49.747 17.806 1.00 28.01 ? 362 PRO A CA 1 ATOM 2659 C C . PRO A 1 326 ? 33.280 50.311 16.562 1.00 30.57 ? 362 PRO A C 1 ATOM 2660 O O . PRO A 1 326 ? 33.741 51.456 16.567 1.00 30.29 ? 362 PRO A O 1 ATOM 2661 C CB . PRO A 1 326 ? 31.240 50.413 17.998 1.00 27.47 ? 362 PRO A CB 1 ATOM 2662 C CG . PRO A 1 326 ? 31.560 51.672 18.708 1.00 28.89 ? 362 PRO A CG 1 ATOM 2663 C CD . PRO A 1 326 ? 32.728 51.353 19.624 1.00 29.47 ? 362 PRO A CD 1 ATOM 2664 N N . HIS A 1 327 ? 33.336 49.512 15.499 1.00 28.64 ? 363 HIS A N 1 ATOM 2665 C CA . HIS A 1 327 ? 33.900 49.958 14.243 1.00 28.23 ? 363 HIS A CA 1 ATOM 2666 C C . HIS A 1 327 ? 32.798 49.982 13.194 1.00 29.59 ? 363 HIS A C 1 ATOM 2667 O O . HIS A 1 327 ? 32.309 48.941 12.783 1.00 25.90 ? 363 HIS A O 1 ATOM 2668 C CB . HIS A 1 327 ? 35.046 49.032 13.843 1.00 30.74 ? 363 HIS A CB 1 ATOM 2669 C CG . HIS A 1 327 ? 36.200 49.092 14.792 1.00 30.30 ? 363 HIS A CG 1 ATOM 2670 N ND1 . HIS A 1 327 ? 37.323 49.850 14.547 1.00 30.96 ? 363 HIS A ND1 1 ATOM 2671 C CD2 . HIS A 1 327 ? 36.378 48.534 16.015 1.00 30.99 ? 363 HIS A CD2 1 ATOM 2672 C CE1 . HIS A 1 327 ? 38.158 49.737 15.568 1.00 33.50 ? 363 HIS A CE1 1 ATOM 2673 N NE2 . HIS A 1 327 ? 37.607 48.946 16.474 1.00 32.47 ? 363 HIS A NE2 1 ATOM 2674 N N . PHE A 1 328 ? 32.400 51.175 12.782 1.00 29.25 ? 364 PHE A N 1 ATOM 2675 C CA . PHE A 1 328 ? 31.206 51.326 11.967 1.00 29.74 ? 364 PHE A CA 1 ATOM 2676 C C . PHE A 1 328 ? 31.477 51.147 10.480 1.00 31.27 ? 364 PHE A C 1 ATOM 2677 O O . PHE A 1 328 ? 32.487 51.611 9.964 1.00 26.95 ? 364 PHE A O 1 ATOM 2678 C CB . PHE A 1 328 ? 30.547 52.692 12.239 1.00 29.44 ? 364 PHE A CB 1 ATOM 2679 C CG . PHE A 1 328 ? 29.713 52.713 13.485 1.00 26.86 ? 364 PHE A CG 1 ATOM 2680 C CD1 . PHE A 1 328 ? 30.249 53.133 14.688 1.00 31.83 ? 364 PHE A CD1 1 ATOM 2681 C CD2 . PHE A 1 328 ? 28.397 52.287 13.456 1.00 28.72 ? 364 PHE A CD2 1 ATOM 2682 C CE1 . PHE A 1 328 ? 29.487 53.125 15.846 1.00 31.98 ? 364 PHE A CE1 1 ATOM 2683 C CE2 . PHE A 1 328 ? 27.632 52.287 14.595 1.00 32.86 ? 364 PHE A CE2 1 ATOM 2684 C CZ . PHE A 1 328 ? 28.181 52.705 15.797 1.00 30.61 ? 364 PHE A CZ 1 ATOM 2685 N N . THR A 1 329 ? 30.567 50.469 9.787 1.00 31.22 ? 365 THR A N 1 ATOM 2686 C CA . THR A 1 329 ? 30.621 50.448 8.341 1.00 29.26 ? 365 THR A CA 1 ATOM 2687 C C . THR A 1 329 ? 30.403 51.876 7.869 1.00 31.82 ? 365 THR A C 1 ATOM 2688 O O . THR A 1 329 ? 29.812 52.683 8.582 1.00 33.67 ? 365 THR A O 1 ATOM 2689 C CB . THR A 1 329 ? 29.535 49.549 7.767 1.00 32.05 ? 365 THR A CB 1 ATOM 2690 O OG1 . THR A 1 329 ? 28.267 50.008 8.243 1.00 40.45 ? 365 THR A OG1 1 ATOM 2691 C CG2 . THR A 1 329 ? 29.728 48.152 8.255 1.00 25.89 ? 365 THR A CG2 1 ATOM 2692 N N . LEU A 1 330 ? 30.885 52.188 6.672 1.00 33.81 ? 366 LEU A N 1 ATOM 2693 C CA . LEU A 1 330 ? 30.775 53.535 6.109 1.00 36.89 ? 366 LEU A CA 1 ATOM 2694 C C . LEU A 1 330 ? 29.385 54.173 6.223 1.00 37.01 ? 366 LEU A C 1 ATOM 2695 O O . LEU A 1 330 ? 29.261 55.338 6.595 1.00 38.34 ? 366 LEU A O 1 ATOM 2696 C CB . LEU A 1 330 ? 31.197 53.516 4.644 1.00 38.97 ? 366 LEU A CB 1 ATOM 2697 C CG . LEU A 1 330 ? 31.521 54.888 4.066 1.00 45.50 ? 366 LEU A CG 1 ATOM 2698 C CD1 . LEU A 1 330 ? 32.647 55.532 4.881 1.00 49.35 ? 366 LEU A CD1 1 ATOM 2699 C CD2 . LEU A 1 330 ? 31.907 54.764 2.599 1.00 42.28 ? 366 LEU A CD2 1 ATOM 2700 N N . ASP A 1 331 ? 28.344 53.417 5.890 1.00 37.03 ? 367 ASP A N 1 ATOM 2701 C CA . ASP A 1 331 ? 26.977 53.947 5.906 1.00 36.11 ? 367 ASP A CA 1 ATOM 2702 C C . ASP A 1 331 ? 26.420 54.152 7.318 1.00 35.26 ? 367 ASP A C 1 ATOM 2703 O O . ASP A 1 331 ? 25.412 54.833 7.503 1.00 34.25 ? 367 ASP A O 1 ATOM 2704 C CB . ASP A 1 331 ? 26.031 53.068 5.070 1.00 35.63 ? 367 ASP A CB 1 ATOM 2705 C CG . ASP A 1 331 ? 26.029 51.609 5.510 1.00 39.18 ? 367 ASP A CG 1 ATOM 2706 O OD1 . ASP A 1 331 ? 26.173 51.346 6.722 1.00 35.32 ? 367 ASP A OD1 1 ATOM 2707 O OD2 . ASP A 1 331 ? 25.874 50.711 4.640 1.00 40.94 ? 367 ASP A OD2 1 ATOM 2708 N N . GLY A 1 332 ? 27.073 53.557 8.310 1.00 32.20 ? 368 GLY A N 1 ATOM 2709 C CA . GLY A 1 332 ? 26.687 53.756 9.695 1.00 30.72 ? 368 GLY A CA 1 ATOM 2710 C C . GLY A 1 332 ? 25.551 52.877 10.185 1.00 33.84 ? 368 GLY A C 1 ATOM 2711 O O . GLY A 1 332 ? 25.090 53.053 11.308 1.00 31.12 ? 368 GLY A O 1 ATOM 2712 N N . ASN A 1 333 ? 25.112 51.926 9.359 1.00 30.30 ? 369 ASN A N 1 ATOM 2713 C CA . ASN A 1 333 ? 23.985 51.051 9.696 1.00 28.13 ? 369 ASN A CA 1 ATOM 2714 C C . ASN A 1 333 ? 24.406 49.756 10.360 1.00 27.86 ? 369 ASN A C 1 ATOM 2715 O O . ASN A 1 333 ? 23.564 48.972 10.771 1.00 28.66 ? 369 ASN A O 1 ATOM 2716 C CB . ASN A 1 333 ? 23.185 50.677 8.437 1.00 30.66 ? 369 ASN A CB 1 ATOM 2717 C CG . ASN A 1 333 ? 22.524 51.872 7.787 1.00 34.75 ? 369 ASN A CG 1 ATOM 2718 O OD1 . ASN A 1 333 ? 22.154 52.825 8.468 1.00 36.91 ? 369 ASN A OD1 1 ATOM 2719 N ND2 . ASN A 1 333 ? 22.365 51.825 6.464 1.00 36.13 ? 369 ASN A ND2 1 ATOM 2720 N N . SER A 1 334 ? 25.704 49.501 10.443 1.00 29.24 ? 370 SER A N 1 ATOM 2721 C CA . SER A 1 334 ? 26.166 48.306 11.150 1.00 28.62 ? 370 SER A CA 1 ATOM 2722 C C . SER A 1 334 ? 27.571 48.521 11.681 1.00 27.24 ? 370 SER A C 1 ATOM 2723 O O . SER A 1 334 ? 28.254 49.465 11.292 1.00 27.24 ? 370 SER A O 1 ATOM 2724 C CB . SER A 1 334 ? 26.121 47.072 10.241 1.00 27.24 ? 370 SER A CB 1 ATOM 2725 O OG . SER A 1 334 ? 26.859 47.297 9.065 1.00 28.01 ? 370 SER A OG 1 ATOM 2726 N N . PHE A 1 335 ? 28.004 47.648 12.576 1.00 24.28 ? 371 PHE A N 1 ATOM 2727 C CA . PHE A 1 335 ? 29.335 47.791 13.142 1.00 26.85 ? 371 PHE A CA 1 ATOM 2728 C C . PHE A 1 335 ? 29.904 46.461 13.596 1.00 28.39 ? 371 PHE A C 1 ATOM 2729 O O . PHE A 1 335 ? 29.179 45.468 13.706 1.00 28.65 ? 371 PHE A O 1 ATOM 2730 C CB . PHE A 1 335 ? 29.325 48.806 14.294 1.00 26.54 ? 371 PHE A CB 1 ATOM 2731 C CG . PHE A 1 335 ? 28.391 48.445 15.424 1.00 27.85 ? 371 PHE A CG 1 ATOM 2732 C CD1 . PHE A 1 335 ? 27.059 48.831 15.390 1.00 27.02 ? 371 PHE A CD1 1 ATOM 2733 C CD2 . PHE A 1 335 ? 28.853 47.747 16.524 1.00 27.64 ? 371 PHE A CD2 1 ATOM 2734 C CE1 . PHE A 1 335 ? 26.211 48.519 16.424 1.00 30.87 ? 371 PHE A CE1 1 ATOM 2735 C CE2 . PHE A 1 335 ? 28.006 47.422 17.570 1.00 29.65 ? 371 PHE A CE2 1 ATOM 2736 C CZ . PHE A 1 335 ? 26.688 47.805 17.527 1.00 29.60 ? 371 PHE A CZ 1 ATOM 2737 N N . TYR A 1 336 ? 31.214 46.450 13.834 1.00 26.35 ? 372 TYR A N 1 ATOM 2738 C CA . TYR A 1 336 ? 31.924 45.270 14.290 1.00 27.38 ? 372 TYR A CA 1 ATOM 2739 C C . TYR A 1 336 ? 32.561 45.618 15.614 1.00 28.91 ? 372 TYR A C 1 ATOM 2740 O O . TYR A 1 336 ? 33.051 46.731 15.803 1.00 27.22 ? 372 TYR A O 1 ATOM 2741 C CB . TYR A 1 336 ? 33.014 44.885 13.297 1.00 25.13 ? 372 TYR A CB 1 ATOM 2742 C CG . TYR A 1 336 ? 32.483 44.559 11.922 1.00 27.51 ? 372 TYR A CG 1 ATOM 2743 C CD1 . TYR A 1 336 ? 32.176 45.573 11.025 1.00 25.69 ? 372 TYR A CD1 1 ATOM 2744 C CD2 . TYR A 1 336 ? 32.290 43.244 11.516 1.00 28.03 ? 372 TYR A CD2 1 ATOM 2745 C CE1 . TYR A 1 336 ? 31.688 45.292 9.769 1.00 27.14 ? 372 TYR A CE1 1 ATOM 2746 C CE2 . TYR A 1 336 ? 31.800 42.957 10.239 1.00 25.93 ? 372 TYR A CE2 1 ATOM 2747 C CZ . TYR A 1 336 ? 31.504 43.993 9.379 1.00 25.93 ? 372 TYR A CZ 1 ATOM 2748 O OH . TYR A 1 336 ? 30.998 43.751 8.114 1.00 28.19 ? 372 TYR A OH 1 ATOM 2749 N N . LYS A 1 337 ? 32.559 44.681 16.543 1.00 29.97 ? 373 LYS A N 1 ATOM 2750 C CA . LYS A 1 337 ? 33.163 44.965 17.833 1.00 29.80 ? 373 LYS A CA 1 ATOM 2751 C C . LYS A 1 337 ? 33.559 43.651 18.472 1.00 27.46 ? 373 LYS A C 1 ATOM 2752 O O . LYS A 1 337 ? 32.943 42.623 18.192 1.00 32.97 ? 373 LYS A O 1 ATOM 2753 C CB . LYS A 1 337 ? 32.210 45.825 18.681 1.00 31.66 ? 373 LYS A CB 1 ATOM 2754 C CG . LYS A 1 337 ? 31.614 45.198 19.907 1.00 34.39 ? 373 LYS A CG 1 ATOM 2755 C CD . LYS A 1 337 ? 30.438 46.062 20.429 1.00 35.33 ? 373 LYS A CD 1 ATOM 2756 C CE . LYS A 1 337 ? 30.890 47.256 21.238 1.00 38.09 ? 373 LYS A CE 1 ATOM 2757 N NZ . LYS A 1 337 ? 31.205 46.892 22.672 1.00 38.23 ? 373 LYS A NZ 1 ATOM 2758 N N . ILE A 1 338 ? 34.646 43.662 19.237 1.00 23.48 ? 374 ILE A N 1 ATOM 2759 C CA . ILE A 1 338 ? 35.131 42.456 19.896 1.00 25.74 ? 374 ILE A CA 1 ATOM 2760 C C . ILE A 1 338 ? 34.261 42.158 21.107 1.00 30.22 ? 374 ILE A C 1 ATOM 2761 O O . ILE A 1 338 ? 34.010 43.044 21.916 1.00 26.61 ? 374 ILE A O 1 ATOM 2762 C CB . ILE A 1 338 ? 36.580 42.643 20.377 1.00 27.90 ? 374 ILE A CB 1 ATOM 2763 C CG1 . ILE A 1 338 ? 37.513 42.807 19.183 1.00 25.11 ? 374 ILE A CG1 1 ATOM 2764 C CG2 . ILE A 1 338 ? 37.026 41.479 21.236 1.00 27.27 ? 374 ILE A CG2 1 ATOM 2765 C CD1 . ILE A 1 338 ? 38.927 43.177 19.575 1.00 23.56 ? 374 ILE A CD1 1 ATOM 2766 N N . ILE A 1 339 ? 33.837 40.904 21.233 1.00 29.75 ? 375 ILE A N 1 ATOM 2767 C CA . ILE A 1 339 ? 32.895 40.457 22.253 1.00 27.27 ? 375 ILE A CA 1 ATOM 2768 C C . ILE A 1 339 ? 33.320 39.064 22.699 1.00 31.87 ? 375 ILE A C 1 ATOM 2769 O O . ILE A 1 339 ? 33.695 38.240 21.862 1.00 27.50 ? 375 ILE A O 1 ATOM 2770 C CB . ILE A 1 339 ? 31.459 40.313 21.651 1.00 26.92 ? 375 ILE A CB 1 ATOM 2771 C CG1 . ILE A 1 339 ? 30.887 41.676 21.289 1.00 32.67 ? 375 ILE A CG1 1 ATOM 2772 C CG2 . ILE A 1 339 ? 30.510 39.610 22.623 1.00 31.55 ? 375 ILE A CG2 1 ATOM 2773 C CD1 . ILE A 1 339 ? 30.645 42.576 22.469 1.00 33.74 ? 375 ILE A CD1 1 ATOM 2774 N N . SER A 1 340 ? 33.243 38.787 24.002 1.00 27.05 ? 376 SER A N 1 ATOM 2775 C CA . SER A 1 340 ? 33.514 37.444 24.518 1.00 28.16 ? 376 SER A CA 1 ATOM 2776 C C . SER A 1 340 ? 32.432 36.469 24.030 1.00 28.74 ? 376 SER A C 1 ATOM 2777 O O . SER A 1 340 ? 31.247 36.747 24.148 1.00 33.29 ? 376 SER A O 1 ATOM 2778 C CB . SER A 1 340 ? 33.536 37.483 26.050 1.00 33.23 ? 376 SER A CB 1 ATOM 2779 O OG . SER A 1 340 ? 33.937 36.242 26.601 1.00 35.65 ? 376 SER A OG 1 ATOM 2780 N N . ASN A 1 341 ? 32.821 35.334 23.469 1.00 31.99 ? 377 ASN A N 1 ATOM 2781 C CA . ASN A 1 341 ? 31.813 34.417 22.941 1.00 32.33 ? 377 ASN A CA 1 ATOM 2782 C C . ASN A 1 341 ? 31.354 33.431 23.999 1.00 37.76 ? 377 ASN A C 1 ATOM 2783 O O . ASN A 1 341 ? 31.655 33.601 25.177 1.00 34.20 ? 377 ASN A O 1 ATOM 2784 C CB . ASN A 1 341 ? 32.279 33.689 21.678 1.00 30.05 ? 377 ASN A CB 1 ATOM 2785 C CG . ASN A 1 341 ? 33.392 32.696 21.934 1.00 32.78 ? 377 ASN A CG 1 ATOM 2786 O OD1 . ASN A 1 341 ? 33.652 32.304 23.072 1.00 31.17 ? 377 ASN A OD1 1 ATOM 2787 N ND2 . ASN A 1 341 ? 34.060 32.271 20.857 1.00 35.81 ? 377 ASN A ND2 1 ATOM 2788 N N . GLU A 1 342 ? 30.632 32.402 23.572 1.00 34.92 ? 378 GLU A N 1 ATOM 2789 C CA . GLU A 1 342 ? 30.026 31.448 24.497 1.00 40.16 ? 378 GLU A CA 1 ATOM 2790 C C . GLU A 1 342 ? 31.072 30.592 25.212 1.00 37.57 ? 378 GLU A C 1 ATOM 2791 O O . GLU A 1 342 ? 30.803 30.041 26.274 1.00 42.53 ? 378 GLU A O 1 ATOM 2792 C CB . GLU A 1 342 ? 29.011 30.563 23.759 1.00 42.14 ? 378 GLU A CB 1 ATOM 2793 C CG . GLU A 1 342 ? 28.135 29.723 24.678 1.00 48.94 ? 378 GLU A CG 1 ATOM 2794 N N . GLU A 1 343 ? 32.266 30.489 24.636 1.00 34.12 ? 379 GLU A N 1 ATOM 2795 C CA . GLU A 1 343 ? 33.358 29.750 25.265 1.00 36.87 ? 379 GLU A CA 1 ATOM 2796 C C . GLU A 1 343 ? 34.276 30.647 26.097 1.00 37.94 ? 379 GLU A C 1 ATOM 2797 O O . GLU A 1 343 ? 35.287 30.179 26.615 1.00 35.58 ? 379 GLU A O 1 ATOM 2798 C CB . GLU A 1 343 ? 34.206 29.031 24.219 1.00 41.54 ? 379 GLU A CB 1 ATOM 2799 C CG . GLU A 1 343 ? 33.855 27.573 24.020 1.00 52.42 ? 379 GLU A CG 1 ATOM 2800 C CD . GLU A 1 343 ? 32.675 27.389 23.096 1.00 63.55 ? 379 GLU A CD 1 ATOM 2801 O OE1 . GLU A 1 343 ? 32.261 28.386 22.452 1.00 57.79 ? 379 GLU A OE1 1 ATOM 2802 O OE2 . GLU A 1 343 ? 32.164 26.246 23.012 1.00 74.75 ? 379 GLU A OE2 1 ATOM 2803 N N . GLY A 1 344 ? 33.930 31.928 26.215 1.00 35.05 ? 380 GLY A N 1 ATOM 2804 C CA . GLY A 1 344 ? 34.769 32.885 26.920 1.00 35.41 ? 380 GLY A CA 1 ATOM 2805 C C . GLY A 1 344 ? 35.975 33.408 26.135 1.00 35.44 ? 380 GLY A C 1 ATOM 2806 O O . GLY A 1 344 ? 36.893 33.990 26.725 1.00 33.70 ? 380 GLY A O 1 ATOM 2807 N N . TYR A 1 345 ? 35.987 33.200 24.818 1.00 31.80 ? 381 TYR A N 1 ATOM 2808 C CA . TYR A 1 345 ? 37.047 33.736 23.962 1.00 30.51 ? 381 TYR A CA 1 ATOM 2809 C C . TYR A 1 345 ? 36.567 34.960 23.200 1.00 31.18 ? 381 TYR A C 1 ATOM 2810 O O . TYR A 1 345 ? 35.476 34.957 22.616 1.00 27.93 ? 381 TYR A O 1 ATOM 2811 C CB . TYR A 1 345 ? 37.594 32.671 23.004 1.00 30.58 ? 381 TYR A CB 1 ATOM 2812 C CG . TYR A 1 345 ? 38.350 31.569 23.726 1.00 33.62 ? 381 TYR A CG 1 ATOM 2813 C CD1 . TYR A 1 345 ? 37.681 30.462 24.235 1.00 33.62 ? 381 TYR A CD1 1 ATOM 2814 C CD2 . TYR A 1 345 ? 39.731 31.646 23.911 1.00 34.05 ? 381 TYR A CD2 1 ATOM 2815 C CE1 . TYR A 1 345 ? 38.367 29.452 24.914 1.00 35.55 ? 381 TYR A CE1 1 ATOM 2816 C CE2 . TYR A 1 345 ? 40.432 30.639 24.587 1.00 33.55 ? 381 TYR A CE2 1 ATOM 2817 C CZ . TYR A 1 345 ? 39.734 29.545 25.085 1.00 35.00 ? 381 TYR A CZ 1 ATOM 2818 O OH . TYR A 1 345 ? 40.402 28.540 25.748 1.00 39.10 ? 381 TYR A OH 1 ATOM 2819 N N . ARG A 1 346 ? 37.389 36.004 23.205 1.00 28.48 ? 382 ARG A N 1 ATOM 2820 C CA . ARG A 1 346 ? 37.016 37.282 22.613 1.00 27.98 ? 382 ARG A CA 1 ATOM 2821 C C . ARG A 1 346 ? 37.178 37.277 21.101 1.00 28.68 ? 382 ARG A C 1 ATOM 2822 O O . ARG A 1 346 ? 38.285 37.117 20.572 1.00 27.62 ? 382 ARG A O 1 ATOM 2823 C CB . ARG A 1 346 ? 37.803 38.424 23.266 1.00 29.24 ? 382 ARG A CB 1 ATOM 2824 C CG . ARG A 1 346 ? 37.252 38.769 24.656 1.00 28.18 ? 382 ARG A CG 1 ATOM 2825 C CD . ARG A 1 346 ? 38.257 39.393 25.620 1.00 32.41 ? 382 ARG A CD 1 ATOM 2826 N NE . ARG A 1 346 ? 37.720 39.182 26.958 1.00 32.48 ? 382 ARG A NE 1 ATOM 2827 C CZ . ARG A 1 346 ? 36.708 39.880 27.457 1.00 33.79 ? 382 ARG A CZ 1 ATOM 2828 N NH1 . ARG A 1 346 ? 36.176 40.879 26.751 1.00 32.93 ? 382 ARG A NH1 1 ATOM 2829 N NH2 . ARG A 1 346 ? 36.239 39.591 28.660 1.00 32.62 ? 382 ARG A NH2 1 ATOM 2830 N N . HIS A 1 347 ? 36.061 37.450 20.403 1.00 28.36 ? 383 HIS A N 1 ATOM 2831 C CA . HIS A 1 347 ? 36.079 37.396 18.945 1.00 31.17 ? 383 HIS A CA 1 ATOM 2832 C C . HIS A 1 347 ? 35.276 38.525 18.331 1.00 29.55 ? 383 HIS A C 1 ATOM 2833 O O . HIS A 1 347 ? 34.545 39.228 19.032 1.00 30.29 ? 383 HIS A O 1 ATOM 2834 C CB . HIS A 1 347 ? 35.566 36.042 18.465 1.00 29.55 ? 383 HIS A CB 1 ATOM 2835 C CG . HIS A 1 347 ? 36.583 34.950 18.568 1.00 29.75 ? 383 HIS A CG 1 ATOM 2836 N ND1 . HIS A 1 347 ? 37.598 34.792 17.646 1.00 28.94 ? 383 HIS A ND1 1 ATOM 2837 C CD2 . HIS A 1 347 ? 36.744 33.965 19.483 1.00 27.86 ? 383 HIS A CD2 1 ATOM 2838 C CE1 . HIS A 1 347 ? 38.345 33.758 17.993 1.00 31.42 ? 383 HIS A CE1 1 ATOM 2839 N NE2 . HIS A 1 347 ? 37.846 33.236 19.103 1.00 28.68 ? 383 HIS A NE2 1 ATOM 2840 N N . ILE A 1 348 ? 35.431 38.704 17.023 1.00 27.44 ? 384 ILE A N 1 ATOM 2841 C CA . ILE A 1 348 ? 34.751 39.775 16.310 1.00 28.69 ? 384 ILE A CA 1 ATOM 2842 C C . ILE A 1 348 ? 33.297 39.440 16.028 1.00 30.01 ? 384 ILE A C 1 ATOM 2843 O O . ILE A 1 348 ? 32.977 38.391 15.460 1.00 29.27 ? 384 ILE A O 1 ATOM 2844 C CB . ILE A 1 348 ? 35.441 40.120 14.994 1.00 30.42 ? 384 ILE A CB 1 ATOM 2845 C CG1 . ILE A 1 348 ? 36.876 40.552 15.258 1.00 30.13 ? 384 ILE A CG1 1 ATOM 2846 C CG2 . ILE A 1 348 ? 34.689 41.221 14.285 1.00 30.63 ? 384 ILE A CG2 1 ATOM 2847 C CD1 . ILE A 1 348 ? 37.726 40.576 14.009 1.00 29.40 ? 384 ILE A CD1 1 ATOM 2848 N N . CYS A 1 349 ? 32.431 40.367 16.421 1.00 31.08 ? 385 CYS A N 1 ATOM 2849 C CA . CYS A 1 349 ? 30.995 40.230 16.294 1.00 28.22 ? 385 CYS A CA 1 ATOM 2850 C C . CYS A 1 349 ? 30.447 41.284 15.334 1.00 31.98 ? 385 CYS A C 1 ATOM 2851 O O . CYS A 1 349 ? 30.862 42.440 15.376 1.00 31.46 ? 385 CYS A O 1 ATOM 2852 C CB . CYS A 1 349 ? 30.359 40.401 17.667 1.00 35.68 ? 385 CYS A CB 1 ATOM 2853 S SG . CYS A 1 349 ? 28.984 39.316 17.938 1.00 50.79 ? 385 CYS A SG 1 ATOM 2854 N N . TYR A 1 350 ? 29.521 40.878 14.469 1.00 27.13 ? 386 TYR A N 1 ATOM 2855 C CA . TYR A 1 350 ? 28.904 41.788 13.503 1.00 26.60 ? 386 TYR A CA 1 ATOM 2856 C C . TYR A 1 350 ? 27.494 42.184 13.952 1.00 30.13 ? 386 TYR A C 1 ATOM 2857 O O . TYR A 1 350 ? 26.645 41.318 14.175 1.00 31.77 ? 386 TYR A O 1 ATOM 2858 C CB . TYR A 1 350 ? 28.858 41.117 12.127 1.00 27.76 ? 386 TYR A CB 1 ATOM 2859 C CG . TYR A 1 350 ? 28.093 41.875 11.065 1.00 24.85 ? 386 TYR A CG 1 ATOM 2860 C CD1 . TYR A 1 350 ? 28.424 43.186 10.733 1.00 26.34 ? 386 TYR A CD1 1 ATOM 2861 C CD2 . TYR A 1 350 ? 27.062 41.268 10.377 1.00 24.96 ? 386 TYR A CD2 1 ATOM 2862 C CE1 . TYR A 1 350 ? 27.738 43.874 9.741 1.00 27.38 ? 386 TYR A CE1 1 ATOM 2863 C CE2 . TYR A 1 350 ? 26.366 41.944 9.381 1.00 28.43 ? 386 TYR A CE2 1 ATOM 2864 C CZ . TYR A 1 350 ? 26.715 43.244 9.065 1.00 29.05 ? 386 TYR A CZ 1 ATOM 2865 O OH . TYR A 1 350 ? 26.016 43.915 8.091 1.00 32.97 ? 386 TYR A OH 1 ATOM 2866 N N . PHE A 1 351 ? 27.260 43.488 14.100 1.00 25.75 ? 387 PHE A N 1 ATOM 2867 C CA . PHE A 1 351 ? 25.997 44.010 14.607 1.00 26.11 ? 387 PHE A CA 1 ATOM 2868 C C . PHE A 1 351 ? 25.291 44.795 13.513 1.00 29.68 ? 387 PHE A C 1 ATOM 2869 O O . PHE A 1 351 ? 25.903 45.623 12.833 1.00 27.89 ? 387 PHE A O 1 ATOM 2870 C CB . PHE A 1 351 ? 26.233 44.990 15.769 1.00 30.79 ? 387 PHE A CB 1 ATOM 2871 C CG . PHE A 1 351 ? 26.673 44.344 17.057 1.00 31.32 ? 387 PHE A CG 1 ATOM 2872 C CD1 . PHE A 1 351 ? 27.999 44.000 17.260 1.00 31.75 ? 387 PHE A CD1 1 ATOM 2873 C CD2 . PHE A 1 351 ? 25.765 44.126 18.082 1.00 35.84 ? 387 PHE A CD2 1 ATOM 2874 C CE1 . PHE A 1 351 ? 28.405 43.423 18.454 1.00 32.91 ? 387 PHE A CE1 1 ATOM 2875 C CE2 . PHE A 1 351 ? 26.166 43.557 19.276 1.00 40.15 ? 387 PHE A CE2 1 ATOM 2876 C CZ . PHE A 1 351 ? 27.486 43.204 19.461 1.00 38.18 ? 387 PHE A CZ 1 ATOM 2877 N N . GLN A 1 352 ? 24.001 44.549 13.343 1.00 26.86 ? 388 GLN A N 1 ATOM 2878 C CA . GLN A 1 352 ? 23.206 45.386 12.462 1.00 29.85 ? 388 GLN A CA 1 ATOM 2879 C C . GLN A 1 352 ? 22.258 46.229 13.300 1.00 32.75 ? 388 GLN A C 1 ATOM 2880 O O . GLN A 1 352 ? 21.535 45.709 14.143 1.00 34.89 ? 388 GLN A O 1 ATOM 2881 C CB . GLN A 1 352 ? 22.456 44.529 11.445 1.00 30.32 ? 388 GLN A CB 1 ATOM 2882 C CG . GLN A 1 352 ? 23.401 43.817 10.489 1.00 28.84 ? 388 GLN A CG 1 ATOM 2883 C CD . GLN A 1 352 ? 22.675 43.091 9.390 1.00 30.82 ? 388 GLN A CD 1 ATOM 2884 O OE1 . GLN A 1 352 ? 23.121 43.080 8.241 1.00 32.04 ? 388 GLN A OE1 1 ATOM 2885 N NE2 . GLN A 1 352 ? 21.557 42.467 9.734 1.00 27.57 ? 388 GLN A NE2 1 ATOM 2886 N N . ILE A 1 353 ? 22.288 47.536 13.092 1.00 31.64 ? 389 ILE A N 1 ATOM 2887 C CA . ILE A 1 353 ? 21.474 48.436 13.904 1.00 34.71 ? 389 ILE A CA 1 ATOM 2888 C C . ILE A 1 353 ? 19.994 48.155 13.660 1.00 38.46 ? 389 ILE A C 1 ATOM 2889 O O . ILE A 1 353 ? 19.581 48.011 12.516 1.00 34.62 ? 389 ILE A O 1 ATOM 2890 C CB . ILE A 1 353 ? 21.816 49.904 13.587 1.00 35.85 ? 389 ILE A CB 1 ATOM 2891 C CG1 . ILE A 1 353 ? 23.177 50.236 14.193 1.00 34.53 ? 389 ILE A CG1 1 ATOM 2892 C CG2 . ILE A 1 353 ? 20.729 50.843 14.107 1.00 38.52 ? 389 ILE A CG2 1 ATOM 2893 C CD1 . ILE A 1 353 ? 23.517 51.698 14.189 1.00 36.83 ? 389 ILE A CD1 1 ATOM 2894 N N . ASP A 1 354 ? 19.212 48.048 14.734 1.00 39.13 ? 390 ASP A N 1 ATOM 2895 C CA . ASP A 1 354 ? 17.786 47.706 14.647 1.00 39.90 ? 390 ASP A CA 1 ATOM 2896 C C . ASP A 1 354 ? 17.508 46.208 14.525 1.00 43.47 ? 390 ASP A C 1 ATOM 2897 O O . ASP A 1 354 ? 16.365 45.806 14.330 1.00 42.93 ? 390 ASP A O 1 ATOM 2898 C CB . ASP A 1 354 ? 17.089 48.455 13.502 1.00 39.66 ? 390 ASP A CB 1 ATOM 2899 C CG . ASP A 1 354 ? 16.990 49.952 13.756 1.00 46.45 ? 390 ASP A CG 1 ATOM 2900 O OD1 . ASP A 1 354 ? 16.984 50.360 14.941 1.00 48.11 ? 390 ASP A OD1 1 ATOM 2901 O OD2 . ASP A 1 354 ? 16.926 50.722 12.773 1.00 46.82 ? 390 ASP A OD2 1 ATOM 2902 N N . LYS A 1 355 ? 18.543 45.380 14.629 1.00 41.19 ? 391 LYS A N 1 ATOM 2903 C CA . LYS A 1 355 ? 18.349 43.932 14.597 1.00 43.51 ? 391 LYS A CA 1 ATOM 2904 C C . LYS A 1 355 ? 18.929 43.317 15.869 1.00 46.29 ? 391 LYS A C 1 ATOM 2905 O O . LYS A 1 355 ? 19.848 43.874 16.470 1.00 45.17 ? 391 LYS A O 1 ATOM 2906 C CB . LYS A 1 355 ? 18.991 43.310 13.349 1.00 40.08 ? 391 LYS A CB 1 ATOM 2907 C CG . LYS A 1 355 ? 18.357 43.725 12.026 1.00 39.62 ? 391 LYS A CG 1 ATOM 2908 C CD . LYS A 1 355 ? 17.404 42.656 11.514 1.00 49.09 ? 391 LYS A CD 1 ATOM 2909 C CE . LYS A 1 355 ? 16.785 43.054 10.169 1.00 46.42 ? 391 LYS A CE 1 ATOM 2910 N N . LYS A 1 356 ? 18.394 42.167 16.272 1.00 49.84 ? 392 LYS A N 1 ATOM 2911 C CA . LYS A 1 356 ? 18.776 41.560 17.549 1.00 54.06 ? 392 LYS A CA 1 ATOM 2912 C C . LYS A 1 356 ? 20.057 40.740 17.468 1.00 50.46 ? 392 LYS A C 1 ATOM 2913 O O . LYS A 1 356 ? 20.394 40.182 16.422 1.00 51.32 ? 392 LYS A O 1 ATOM 2914 C CB . LYS A 1 356 ? 17.642 40.688 18.114 1.00 55.33 ? 392 LYS A CB 1 ATOM 2915 C CG . LYS A 1 356 ? 17.349 39.410 17.321 1.00 56.27 ? 392 LYS A CG 1 ATOM 2916 C CD . LYS A 1 356 ? 16.408 38.482 18.102 1.00 52.97 ? 392 LYS A CD 1 ATOM 2917 N N . ASP A 1 357 ? 20.758 40.661 18.593 1.00 55.34 ? 393 ASP A N 1 ATOM 2918 C CA . ASP A 1 357 ? 21.931 39.811 18.696 1.00 53.49 ? 393 ASP A CA 1 ATOM 2919 C C . ASP A 1 357 ? 22.999 40.298 17.736 1.00 50.64 ? 393 ASP A C 1 ATOM 2920 O O . ASP A 1 357 ? 22.833 41.313 17.063 1.00 52.15 ? 393 ASP A O 1 ATOM 2921 C CB . ASP A 1 357 ? 21.578 38.356 18.358 1.00 55.97 ? 393 ASP A CB 1 ATOM 2922 C CG . ASP A 1 357 ? 20.439 37.809 19.208 1.00 61.71 ? 393 ASP A CG 1 ATOM 2923 O OD1 . ASP A 1 357 ? 20.239 38.303 20.344 1.00 58.87 ? 393 ASP A OD1 1 ATOM 2924 O OD2 . ASP A 1 357 ? 19.747 36.876 18.733 1.00 62.29 ? 393 ASP A OD2 1 ATOM 2925 N N . CYS A 1 358 ? 24.103 39.571 17.676 1.00 46.14 ? 394 CYS A N 1 ATOM 2926 C CA . CYS A 1 358 ? 25.121 39.859 16.690 1.00 39.70 ? 394 CYS A CA 1 ATOM 2927 C C . CYS A 1 358 ? 25.561 38.539 16.086 1.00 38.76 ? 394 CYS A C 1 ATOM 2928 O O . CYS A 1 358 ? 25.155 37.471 16.557 1.00 39.57 ? 394 CYS A O 1 ATOM 2929 C CB . CYS A 1 358 ? 26.298 40.598 17.322 1.00 41.58 ? 394 CYS A CB 1 ATOM 2930 S SG . CYS A 1 358 ? 27.107 39.679 18.666 1.00 52.45 ? 394 CYS A SG 1 ATOM 2931 N N . THR A 1 359 ? 26.381 38.613 15.043 1.00 31.37 ? 395 THR A N 1 ATOM 2932 C CA . THR A 1 359 ? 26.881 37.411 14.393 1.00 30.91 ? 395 THR A CA 1 ATOM 2933 C C . THR A 1 359 ? 28.384 37.352 14.550 1.00 30.15 ? 395 THR A C 1 ATOM 2934 O O . THR A 1 359 ? 29.088 38.243 14.086 1.00 28.44 ? 395 THR A O 1 ATOM 2935 C CB . THR A 1 359 ? 26.569 37.433 12.891 1.00 31.22 ? 395 THR A CB 1 ATOM 2936 O OG1 . THR A 1 359 ? 25.162 37.605 12.709 1.00 31.94 ? 395 THR A OG1 1 ATOM 2937 C CG2 . THR A 1 359 ? 27.027 36.135 12.207 1.00 31.12 ? 395 THR A CG2 1 ATOM 2938 N N . PHE A 1 360 ? 28.873 36.302 15.202 1.00 27.23 ? 396 PHE A N 1 ATOM 2939 C CA . PHE A 1 360 ? 30.303 36.082 15.316 1.00 31.63 ? 396 PHE A CA 1 ATOM 2940 C C . PHE A 1 360 ? 30.912 35.705 13.986 1.00 33.53 ? 396 PHE A C 1 ATOM 2941 O O . PHE A 1 360 ? 30.534 34.688 13.401 1.00 31.59 ? 396 PHE A O 1 ATOM 2942 C CB . PHE A 1 360 ? 30.588 34.986 16.333 1.00 31.25 ? 396 PHE A CB 1 ATOM 2943 C CG . PHE A 1 360 ? 30.593 35.476 17.734 1.00 31.73 ? 396 PHE A CG 1 ATOM 2944 C CD1 . PHE A 1 360 ? 31.616 36.296 18.179 1.00 31.75 ? 396 PHE A CD1 1 ATOM 2945 C CD2 . PHE A 1 360 ? 29.572 35.139 18.602 1.00 34.60 ? 396 PHE A CD2 1 ATOM 2946 C CE1 . PHE A 1 360 ? 31.630 36.769 19.476 1.00 33.05 ? 396 PHE A CE1 1 ATOM 2947 C CE2 . PHE A 1 360 ? 29.576 35.606 19.907 1.00 40.00 ? 396 PHE A CE2 1 ATOM 2948 C CZ . PHE A 1 360 ? 30.608 36.429 20.342 1.00 37.62 ? 396 PHE A CZ 1 ATOM 2949 N N . ILE A 1 361 ? 31.865 36.508 13.517 1.00 30.96 ? 397 ILE A N 1 ATOM 2950 C CA . ILE A 1 361 ? 32.525 36.221 12.247 1.00 27.93 ? 397 ILE A CA 1 ATOM 2951 C C . ILE A 1 361 ? 33.891 35.535 12.397 1.00 33.03 ? 397 ILE A C 1 ATOM 2952 O O . ILE A 1 361 ? 34.458 35.054 11.409 1.00 31.97 ? 397 ILE A O 1 ATOM 2953 C CB . ILE A 1 361 ? 32.615 37.492 11.361 1.00 31.27 ? 397 ILE A CB 1 ATOM 2954 C CG1 . ILE A 1 361 ? 33.742 38.412 11.822 1.00 29.01 ? 397 ILE A CG1 1 ATOM 2955 C CG2 . ILE A 1 361 ? 31.287 38.229 11.386 1.00 32.30 ? 397 ILE A CG2 1 ATOM 2956 C CD1 . ILE A 1 361 ? 33.819 39.719 11.058 1.00 28.40 ? 397 ILE A CD1 1 ATOM 2957 N N . THR A 1 362 ? 34.419 35.497 13.622 1.00 27.37 ? 398 THR A N 1 ATOM 2958 C CA . THR A 1 362 ? 35.603 34.691 13.946 1.00 32.32 ? 398 THR A CA 1 ATOM 2959 C C . THR A 1 362 ? 35.337 33.770 15.137 1.00 32.68 ? 398 THR A C 1 ATOM 2960 O O . THR A 1 362 ? 34.438 34.017 15.939 1.00 32.48 ? 398 THR A O 1 ATOM 2961 C CB . THR A 1 362 ? 36.851 35.551 14.283 1.00 28.79 ? 398 THR A CB 1 ATOM 2962 O OG1 . THR A 1 362 ? 36.585 36.364 15.436 1.00 28.48 ? 398 THR A OG1 1 ATOM 2963 C CG2 . THR A 1 362 ? 37.240 36.434 13.100 1.00 32.67 ? 398 THR A CG2 1 ATOM 2964 N N . LYS A 1 363 ? 36.130 32.712 15.259 1.00 33.12 ? 399 LYS A N 1 ATOM 2965 C CA . LYS A 1 363 ? 36.001 31.810 16.397 1.00 33.32 ? 399 LYS A CA 1 ATOM 2966 C C . LYS A 1 363 ? 37.243 30.945 16.567 1.00 34.85 ? 399 LYS A C 1 ATOM 2967 O O . LYS A 1 363 ? 38.075 30.851 15.668 1.00 35.92 ? 399 LYS A O 1 ATOM 2968 C CB . LYS A 1 363 ? 34.774 30.909 16.244 1.00 39.84 ? 399 LYS A CB 1 ATOM 2969 C CG . LYS A 1 363 ? 34.978 29.787 15.235 1.00 43.33 ? 399 LYS A CG 1 ATOM 2970 C CD . LYS A 1 363 ? 33.731 28.912 15.089 1.00 49.77 ? 399 LYS A CD 1 ATOM 2971 C CE . LYS A 1 363 ? 33.852 27.994 13.877 1.00 49.84 ? 399 LYS A CE 1 ATOM 2972 N NZ . LYS A 1 363 ? 33.975 28.795 12.621 1.00 54.42 ? 399 LYS A NZ 1 ATOM 2973 N N . GLY A 1 364 ? 37.359 30.311 17.732 1.00 37.02 ? 400 GLY A N 1 ATOM 2974 C CA . GLY A 1 364 ? 38.471 29.420 18.002 1.00 34.10 ? 400 GLY A CA 1 ATOM 2975 C C . GLY A 1 364 ? 39.021 29.646 19.396 1.00 34.06 ? 400 GLY A C 1 ATOM 2976 O O . GLY A 1 364 ? 38.574 30.536 20.116 1.00 32.13 ? 400 GLY A O 1 ATOM 2977 N N . THR A 1 365 ? 40.000 28.835 19.774 1.00 33.82 ? 401 THR A N 1 ATOM 2978 C CA . THR A 1 365 ? 40.626 28.936 21.080 1.00 35.32 ? 401 THR A CA 1 ATOM 2979 C C . THR A 1 365 ? 41.810 29.897 21.020 1.00 33.17 ? 401 THR A C 1 ATOM 2980 O O . THR A 1 365 ? 42.970 29.491 21.048 1.00 37.06 ? 401 THR A O 1 ATOM 2981 C CB . THR A 1 365 ? 41.094 27.549 21.549 1.00 37.64 ? 401 THR A CB 1 ATOM 2982 O OG1 . THR A 1 365 ? 40.046 26.609 21.323 1.00 42.37 ? 401 THR A OG1 1 ATOM 2983 C CG2 . THR A 1 365 ? 41.392 27.564 23.021 1.00 39.14 ? 401 THR A CG2 1 ATOM 2984 N N . TRP A 1 366 ? 41.502 31.178 20.912 1.00 30.82 ? 402 TRP A N 1 ATOM 2985 C CA . TRP A 1 366 ? 42.506 32.221 20.758 1.00 26.55 ? 402 TRP A CA 1 ATOM 2986 C C . TRP A 1 366 ? 41.682 33.475 20.700 1.00 29.28 ? 402 TRP A C 1 ATOM 2987 O O . TRP A 1 366 ? 40.454 33.394 20.624 1.00 28.52 ? 402 TRP A O 1 ATOM 2988 C CB . TRP A 1 366 ? 43.329 32.040 19.471 1.00 30.49 ? 402 TRP A CB 1 ATOM 2989 C CG . TRP A 1 366 ? 42.530 31.857 18.180 1.00 27.26 ? 402 TRP A CG 1 ATOM 2990 C CD1 . TRP A 1 366 ? 42.201 30.661 17.576 1.00 29.68 ? 402 TRP A CD1 1 ATOM 2991 C CD2 . TRP A 1 366 ? 41.993 32.894 17.328 1.00 26.15 ? 402 TRP A CD2 1 ATOM 2992 N NE1 . TRP A 1 366 ? 41.483 30.899 16.424 1.00 31.46 ? 402 TRP A NE1 1 ATOM 2993 C CE2 . TRP A 1 366 ? 41.344 32.253 16.247 1.00 31.81 ? 402 TRP A CE2 1 ATOM 2994 C CE3 . TRP A 1 366 ? 41.987 34.292 17.381 1.00 26.77 ? 402 TRP A CE3 1 ATOM 2995 C CZ2 . TRP A 1 366 ? 40.705 32.967 15.229 1.00 29.32 ? 402 TRP A CZ2 1 ATOM 2996 C CZ3 . TRP A 1 366 ? 41.350 34.996 16.378 1.00 28.05 ? 402 TRP A CZ3 1 ATOM 2997 C CH2 . TRP A 1 366 ? 40.716 34.335 15.316 1.00 28.91 ? 402 TRP A CH2 1 ATOM 2998 N N . GLU A 1 367 ? 42.316 34.635 20.758 1.00 26.25 ? 403 GLU A N 1 ATOM 2999 C CA . GLU A 1 367 ? 41.534 35.855 20.853 1.00 26.78 ? 403 GLU A CA 1 ATOM 3000 C C . GLU A 1 367 ? 41.942 36.897 19.826 1.00 27.52 ? 403 GLU A C 1 ATOM 3001 O O . GLU A 1 367 ? 43.102 36.953 19.401 1.00 26.44 ? 403 GLU A O 1 ATOM 3002 C CB . GLU A 1 367 ? 41.603 36.444 22.274 1.00 27.77 ? 403 GLU A CB 1 ATOM 3003 C CG . GLU A 1 367 ? 41.022 35.520 23.369 1.00 30.92 ? 403 GLU A CG 1 ATOM 3004 C CD . GLU A 1 367 ? 40.719 36.255 24.669 1.00 33.33 ? 403 GLU A CD 1 ATOM 3005 O OE1 . GLU A 1 367 ? 41.545 37.095 25.084 1.00 35.47 ? 403 GLU A OE1 1 ATOM 3006 O OE2 . GLU A 1 367 ? 39.643 36.011 25.261 1.00 31.09 ? 403 GLU A OE2 1 ATOM 3007 N N . VAL A 1 368 ? 40.975 37.722 19.438 1.00 23.76 ? 404 VAL A N 1 ATOM 3008 C CA . VAL A 1 368 ? 41.251 38.904 18.639 1.00 24.14 ? 404 VAL A CA 1 ATOM 3009 C C . VAL A 1 368 ? 41.681 40.028 19.583 1.00 25.88 ? 404 VAL A C 1 ATOM 3010 O O . VAL A 1 368 ? 41.013 40.311 20.578 1.00 26.04 ? 404 VAL A O 1 ATOM 3011 C CB . VAL A 1 368 ? 39.999 39.345 17.873 1.00 26.82 ? 404 VAL A CB 1 ATOM 3012 C CG1 . VAL A 1 368 ? 40.286 40.589 17.067 1.00 21.98 ? 404 VAL A CG1 1 ATOM 3013 C CG2 . VAL A 1 368 ? 39.493 38.206 16.987 1.00 25.95 ? 404 VAL A CG2 1 ATOM 3014 N N . ILE A 1 369 ? 42.810 40.647 19.273 1.00 28.60 ? 405 ILE A N 1 ATOM 3015 C CA . ILE A 1 369 ? 43.392 41.705 20.096 1.00 28.99 ? 405 ILE A CA 1 ATOM 3016 C C . ILE A 1 369 ? 42.794 43.074 19.739 1.00 30.04 ? 405 ILE A C 1 ATOM 3017 O O . ILE A 1 369 ? 42.477 43.894 20.607 1.00 25.61 ? 405 ILE A O 1 ATOM 3018 C CB . ILE A 1 369 ? 44.920 41.763 19.878 1.00 31.62 ? 405 ILE A CB 1 ATOM 3019 C CG1 . ILE A 1 369 ? 45.540 40.368 20.063 1.00 28.41 ? 405 ILE A CG1 1 ATOM 3020 C CG2 . ILE A 1 369 ? 45.566 42.844 20.787 1.00 30.79 ? 405 ILE A CG2 1 ATOM 3021 C CD1 . ILE A 1 369 ? 45.291 39.743 21.433 1.00 28.38 ? 405 ILE A CD1 1 ATOM 3022 N N . GLY A 1 370 ? 42.646 43.326 18.447 1.00 24.77 ? 406 GLY A N 1 ATOM 3023 C CA . GLY A 1 370 ? 42.049 44.576 18.020 1.00 25.45 ? 406 GLY A CA 1 ATOM 3024 C C . GLY A 1 370 ? 41.552 44.510 16.598 1.00 28.31 ? 406 GLY A C 1 ATOM 3025 O O . GLY A 1 370 ? 42.093 43.752 15.792 1.00 23.77 ? 406 GLY A O 1 ATOM 3026 N N . ILE A 1 371 ? 40.509 45.282 16.300 1.00 26.27 ? 407 ILE A N 1 ATOM 3027 C CA . ILE A 1 371 ? 40.089 45.487 14.918 1.00 28.82 ? 407 ILE A CA 1 ATOM 3028 C C . ILE A 1 371 ? 40.834 46.711 14.378 1.00 32.65 ? 407 ILE A C 1 ATOM 3029 O O . ILE A 1 371 ? 40.748 47.789 14.974 1.00 30.49 ? 407 ILE A O 1 ATOM 3030 C CB . ILE A 1 371 ? 38.569 45.725 14.824 1.00 29.29 ? 407 ILE A CB 1 ATOM 3031 C CG1 . ILE A 1 371 ? 37.811 44.479 15.268 1.00 29.66 ? 407 ILE A CG1 1 ATOM 3032 C CG2 . ILE A 1 371 ? 38.171 46.104 13.384 1.00 29.84 ? 407 ILE A CG2 1 ATOM 3033 C CD1 . ILE A 1 371 ? 36.311 44.701 15.441 1.00 29.80 ? 407 ILE A CD1 1 ATOM 3034 N N . GLU A 1 372 ? 41.562 46.558 13.266 1.00 30.57 ? 408 GLU A N 1 ATOM 3035 C CA . GLU A 1 372 ? 42.475 47.618 12.807 1.00 26.35 ? 408 GLU A CA 1 ATOM 3036 C C . GLU A 1 372 ? 41.998 48.462 11.629 1.00 30.96 ? 408 GLU A C 1 ATOM 3037 O O . GLU A 1 372 ? 42.357 49.626 11.533 1.00 27.11 ? 408 GLU A O 1 ATOM 3038 C CB . GLU A 1 372 ? 43.862 47.047 12.499 1.00 31.78 ? 408 GLU A CB 1 ATOM 3039 C CG . GLU A 1 372 ? 44.518 46.323 13.692 1.00 28.70 ? 408 GLU A CG 1 ATOM 3040 C CD . GLU A 1 372 ? 44.702 47.219 14.930 1.00 34.39 ? 408 GLU A CD 1 ATOM 3041 O OE1 . GLU A 1 372 ? 45.139 48.391 14.803 1.00 35.93 ? 408 GLU A OE1 1 ATOM 3042 O OE2 . GLU A 1 372 ? 44.409 46.744 16.046 1.00 40.92 ? 408 GLU A OE2 1 ATOM 3043 N N . ALA A 1 373 ? 41.219 47.877 10.720 1.00 28.83 ? 409 ALA A N 1 ATOM 3044 C CA . ALA A 1 373 ? 40.641 48.639 9.620 1.00 25.75 ? 409 ALA A CA 1 ATOM 3045 C C . ALA A 1 373 ? 39.471 47.885 9.021 1.00 25.48 ? 409 ALA A C 1 ATOM 3046 O O . ALA A 1 373 ? 39.334 46.675 9.190 1.00 26.40 ? 409 ALA A O 1 ATOM 3047 C CB . ALA A 1 373 ? 41.696 48.947 8.538 1.00 26.94 ? 409 ALA A CB 1 ATOM 3048 N N . LEU A 1 374 ? 38.624 48.612 8.319 1.00 24.05 ? 410 LEU A N 1 ATOM 3049 C CA . LEU A 1 374 ? 37.431 48.029 7.739 1.00 28.42 ? 410 LEU A CA 1 ATOM 3050 C C . LEU A 1 374 ? 37.264 48.690 6.391 1.00 29.80 ? 410 LEU A C 1 ATOM 3051 O O . LEU A 1 374 ? 37.315 49.915 6.306 1.00 26.01 ? 410 LEU A O 1 ATOM 3052 C CB . LEU A 1 374 ? 36.219 48.316 8.634 1.00 26.22 ? 410 LEU A CB 1 ATOM 3053 C CG . LEU A 1 374 ? 34.851 47.914 8.086 1.00 33.51 ? 410 LEU A CG 1 ATOM 3054 C CD1 . LEU A 1 374 ? 34.771 46.404 7.866 1.00 27.51 ? 410 LEU A CD1 1 ATOM 3055 C CD2 . LEU A 1 374 ? 33.753 48.390 9.025 1.00 30.18 ? 410 LEU A CD2 1 ATOM 3056 N N . THR A 1 375 ? 37.143 47.880 5.339 1.00 27.88 ? 411 THR A N 1 ATOM 3057 C CA . THR A 1 375 ? 36.813 48.377 4.013 1.00 32.00 ? 411 THR A CA 1 ATOM 3058 C C . THR A 1 375 ? 35.550 47.663 3.551 1.00 32.72 ? 411 THR A C 1 ATOM 3059 O O . THR A 1 375 ? 34.975 46.873 4.296 1.00 31.28 ? 411 THR A O 1 ATOM 3060 C CB . THR A 1 375 ? 37.946 48.100 2.998 1.00 35.53 ? 411 THR A CB 1 ATOM 3061 O OG1 . THR A 1 375 ? 38.009 46.695 2.735 1.00 32.61 ? 411 THR A OG1 1 ATOM 3062 C CG2 . THR A 1 375 ? 39.291 48.585 3.547 1.00 31.60 ? 411 THR A CG2 1 ATOM 3063 N N . SER A 1 376 ? 35.118 47.928 2.321 1.00 36.28 ? 412 SER A N 1 ATOM 3064 C CA . SER A 1 376 ? 33.904 47.308 1.814 1.00 37.90 ? 412 SER A CA 1 ATOM 3065 C C . SER A 1 376 ? 34.096 45.800 1.618 1.00 38.78 ? 412 SER A C 1 ATOM 3066 O O . SER A 1 376 ? 33.148 45.027 1.735 1.00 40.08 ? 412 SER A O 1 ATOM 3067 C CB . SER A 1 376 ? 33.458 47.982 0.511 1.00 41.80 ? 412 SER A CB 1 ATOM 3068 O OG . SER A 1 376 ? 34.536 48.079 -0.404 1.00 44.83 ? 412 SER A OG 1 ATOM 3069 N N . ASP A 1 377 ? 35.331 45.388 1.355 1.00 37.16 ? 413 ASP A N 1 ATOM 3070 C CA . ASP A 1 377 ? 35.634 43.988 1.050 1.00 33.14 ? 413 ASP A CA 1 ATOM 3071 C C . ASP A 1 377 ? 36.163 43.180 2.237 1.00 34.34 ? 413 ASP A C 1 ATOM 3072 O O . ASP A 1 377 ? 35.968 41.967 2.301 1.00 29.29 ? 413 ASP A O 1 ATOM 3073 C CB . ASP A 1 377 ? 36.679 43.931 -0.062 1.00 35.94 ? 413 ASP A CB 1 ATOM 3074 C CG . ASP A 1 377 ? 36.220 44.629 -1.328 1.00 46.74 ? 413 ASP A CG 1 ATOM 3075 O OD1 . ASP A 1 377 ? 34.993 44.685 -1.550 1.00 50.62 ? 413 ASP A OD1 1 ATOM 3076 O OD2 . ASP A 1 377 ? 37.077 45.115 -2.104 1.00 54.23 ? 413 ASP A OD2 1 ATOM 3077 N N . TYR A 1 378 ? 36.859 43.846 3.156 1.00 29.98 ? 414 TYR A N 1 ATOM 3078 C CA . TYR A 1 378 ? 37.606 43.142 4.195 1.00 29.46 ? 414 TYR A CA 1 ATOM 3079 C C . TYR A 1 378 ? 37.592 43.882 5.514 1.00 27.77 ? 414 TYR A C 1 ATOM 3080 O O . TYR A 1 378 ? 37.520 45.110 5.542 1.00 28.28 ? 414 TYR A O 1 ATOM 3081 C CB . TYR A 1 378 ? 39.067 42.982 3.781 1.00 31.56 ? 414 TYR A CB 1 ATOM 3082 C CG . TYR A 1 378 ? 39.290 42.016 2.646 1.00 29.07 ? 414 TYR A CG 1 ATOM 3083 C CD1 . TYR A 1 378 ? 39.400 40.650 2.886 1.00 31.35 ? 414 TYR A CD1 1 ATOM 3084 C CD2 . TYR A 1 378 ? 39.388 42.465 1.336 1.00 34.33 ? 414 TYR A CD2 1 ATOM 3085 C CE1 . TYR A 1 378 ? 39.599 39.752 1.845 1.00 35.00 ? 414 TYR A CE1 1 ATOM 3086 C CE2 . TYR A 1 378 ? 39.584 41.578 0.292 1.00 36.20 ? 414 TYR A CE2 1 ATOM 3087 C CZ . TYR A 1 378 ? 39.690 40.221 0.554 1.00 32.93 ? 414 TYR A CZ 1 ATOM 3088 O OH . TYR A 1 378 ? 39.897 39.334 -0.487 1.00 43.38 ? 414 TYR A OH 1 ATOM 3089 N N . LEU A 1 379 ? 37.663 43.119 6.598 1.00 26.77 ? 415 LEU A N 1 ATOM 3090 C CA . LEU A 1 379 ? 37.959 43.664 7.914 1.00 27.71 ? 415 LEU A CA 1 ATOM 3091 C C . LEU A 1 379 ? 39.350 43.169 8.290 1.00 28.53 ? 415 LEU A C 1 ATOM 3092 O O . LEU A 1 379 ? 39.663 41.996 8.082 1.00 27.77 ? 415 LEU A O 1 ATOM 3093 C CB . LEU A 1 379 ? 36.928 43.189 8.931 1.00 26.10 ? 415 LEU A CB 1 ATOM 3094 C CG . LEU A 1 379 ? 37.078 43.686 10.365 1.00 29.45 ? 415 LEU A CG 1 ATOM 3095 C CD1 . LEU A 1 379 ? 35.714 43.712 11.031 1.00 26.31 ? 415 LEU A CD1 1 ATOM 3096 C CD2 . LEU A 1 379 ? 38.064 42.812 11.123 1.00 26.99 ? 415 LEU A CD2 1 ATOM 3097 N N . TYR A 1 380 ? 40.184 44.061 8.821 1.00 25.76 ? 416 TYR A N 1 ATOM 3098 C CA . TYR A 1 380 ? 41.545 43.707 9.211 1.00 27.16 ? 416 TYR A CA 1 ATOM 3099 C C . TYR A 1 380 ? 41.643 43.706 10.731 1.00 27.65 ? 416 TYR A C 1 ATOM 3100 O O . TYR A 1 380 ? 41.160 44.633 11.384 1.00 29.09 ? 416 TYR A O 1 ATOM 3101 C CB . TYR A 1 380 ? 42.547 44.700 8.614 1.00 23.95 ? 416 TYR A CB 1 ATOM 3102 C CG . TYR A 1 380 ? 42.559 44.739 7.100 1.00 29.12 ? 416 TYR A CG 1 ATOM 3103 C CD1 . TYR A 1 380 ? 41.610 45.467 6.397 1.00 28.95 ? 416 TYR A CD1 1 ATOM 3104 C CD2 . TYR A 1 380 ? 43.532 44.059 6.371 1.00 30.09 ? 416 TYR A CD2 1 ATOM 3105 C CE1 . TYR A 1 380 ? 41.614 45.513 5.009 1.00 24.89 ? 416 TYR A CE1 1 ATOM 3106 C CE2 . TYR A 1 380 ? 43.543 44.092 4.986 1.00 26.56 ? 416 TYR A CE2 1 ATOM 3107 C CZ . TYR A 1 380 ? 42.583 44.821 4.314 1.00 31.64 ? 416 TYR A CZ 1 ATOM 3108 O OH . TYR A 1 380 ? 42.594 44.859 2.938 1.00 29.22 ? 416 TYR A OH 1 ATOM 3109 N N . TYR A 1 381 ? 42.250 42.666 11.299 1.00 30.39 ? 417 TYR A N 1 ATOM 3110 C CA . TYR A 1 381 ? 42.356 42.552 12.757 1.00 26.69 ? 417 TYR A CA 1 ATOM 3111 C C . TYR A 1 381 ? 43.678 41.897 13.170 1.00 29.69 ? 417 TYR A C 1 ATOM 3112 O O . TYR A 1 381 ? 44.274 41.157 12.388 1.00 29.46 ? 417 TYR A O 1 ATOM 3113 C CB . TYR A 1 381 ? 41.169 41.753 13.319 1.00 26.51 ? 417 TYR A CB 1 ATOM 3114 C CG . TYR A 1 381 ? 41.145 40.288 12.901 1.00 28.32 ? 417 TYR A CG 1 ATOM 3115 C CD1 . TYR A 1 381 ? 40.571 39.882 11.692 1.00 29.48 ? 417 TYR A CD1 1 ATOM 3116 C CD2 . TYR A 1 381 ? 41.689 39.312 13.721 1.00 26.88 ? 417 TYR A CD2 1 ATOM 3117 C CE1 . TYR A 1 381 ? 40.553 38.532 11.314 1.00 27.26 ? 417 TYR A CE1 1 ATOM 3118 C CE2 . TYR A 1 381 ? 41.678 37.980 13.358 1.00 27.94 ? 417 TYR A CE2 1 ATOM 3119 C CZ . TYR A 1 381 ? 41.119 37.597 12.159 1.00 29.64 ? 417 TYR A CZ 1 ATOM 3120 O OH . TYR A 1 381 ? 41.128 36.264 11.841 1.00 32.71 ? 417 TYR A OH 1 ATOM 3121 N N . ILE A 1 382 ? 44.137 42.201 14.385 1.00 25.13 ? 418 ILE A N 1 ATOM 3122 C CA . ILE A 1 382 ? 45.294 41.543 14.999 1.00 28.45 ? 418 ILE A CA 1 ATOM 3123 C C . ILE A 1 382 ? 44.822 40.435 15.951 1.00 27.99 ? 418 ILE A C 1 ATOM 3124 O O . ILE A 1 382 ? 43.901 40.648 16.737 1.00 26.92 ? 418 ILE A O 1 ATOM 3125 C CB . ILE A 1 382 ? 46.115 42.536 15.846 1.00 30.18 ? 418 ILE A CB 1 ATOM 3126 C CG1 . ILE A 1 382 ? 46.615 43.702 14.987 1.00 30.42 ? 418 ILE A CG1 1 ATOM 3127 C CG2 . ILE A 1 382 ? 47.277 41.824 16.524 1.00 27.40 ? 418 ILE A CG2 1 ATOM 3128 C CD1 . ILE A 1 382 ? 47.759 43.355 14.112 1.00 29.44 ? 418 ILE A CD1 1 ATOM 3129 N N . SER A 1 383 ? 45.449 39.262 15.895 1.00 23.81 ? 419 SER A N 1 ATOM 3130 C CA . SER A 1 383 ? 45.094 38.193 16.811 1.00 24.30 ? 419 SER A CA 1 ATOM 3131 C C . SER A 1 383 ? 46.308 37.373 17.192 1.00 24.10 ? 419 SER A C 1 ATOM 3132 O O . SER A 1 383 ? 47.383 37.523 16.609 1.00 27.30 ? 419 SER A O 1 ATOM 3133 C CB . SER A 1 383 ? 44.042 37.269 16.198 1.00 25.73 ? 419 SER A CB 1 ATOM 3134 O OG . SER A 1 383 ? 44.679 36.293 15.392 1.00 25.04 ? 419 SER A OG 1 ATOM 3135 N N . ASN A 1 384 ? 46.131 36.499 18.173 1.00 23.49 ? 420 ASN A N 1 ATOM 3136 C CA . ASN A 1 384 ? 47.198 35.586 18.573 1.00 27.65 ? 420 ASN A CA 1 ATOM 3137 C C . ASN A 1 384 ? 46.918 34.143 18.125 1.00 28.20 ? 420 ASN A C 1 ATOM 3138 O O . ASN A 1 384 ? 47.324 33.186 18.780 1.00 26.77 ? 420 ASN A O 1 ATOM 3139 C CB . ASN A 1 384 ? 47.506 35.685 20.083 1.00 24.77 ? 420 ASN A CB 1 ATOM 3140 C CG . ASN A 1 384 ? 46.297 35.374 20.972 1.00 30.00 ? 420 ASN A CG 1 ATOM 3141 O OD1 . ASN A 1 384 ? 45.289 34.838 20.515 1.00 26.96 ? 420 ASN A OD1 1 ATOM 3142 N ND2 . ASN A 1 384 ? 46.401 35.724 22.258 1.00 26.92 ? 420 ASN A ND2 1 ATOM 3143 N N . GLU A 1 385 ? 46.218 33.996 17.002 1.00 25.66 ? 421 GLU A N 1 ATOM 3144 C CA . GLU A 1 385 ? 45.898 32.663 16.492 1.00 26.90 ? 421 GLU A CA 1 ATOM 3145 C C . GLU A 1 385 ? 47.149 31.870 16.115 1.00 30.10 ? 421 GLU A C 1 ATOM 3146 O O . GLU A 1 385 ? 47.247 30.679 16.399 1.00 32.99 ? 421 GLU A O 1 ATOM 3147 C CB . GLU A 1 385 ? 44.984 32.746 15.268 1.00 29.86 ? 421 GLU A CB 1 ATOM 3148 C CG . GLU A 1 385 ? 44.647 31.372 14.703 1.00 30.38 ? 421 GLU A CG 1 ATOM 3149 C CD . GLU A 1 385 ? 43.657 31.404 13.541 1.00 34.79 ? 421 GLU A CD 1 ATOM 3150 O OE1 . GLU A 1 385 ? 43.335 32.503 13.028 1.00 30.71 ? 421 GLU A OE1 1 ATOM 3151 O OE2 . GLU A 1 385 ? 43.200 30.308 13.144 1.00 35.44 ? 421 GLU A OE2 1 ATOM 3152 N N . TYR A 1 386 ? 48.108 32.531 15.483 1.00 28.76 ? 422 TYR A N 1 ATOM 3153 C CA . TYR A 1 386 ? 49.235 31.815 14.878 1.00 33.29 ? 422 TYR A CA 1 ATOM 3154 C C . TYR A 1 386 ? 49.967 30.900 15.854 1.00 37.55 ? 422 TYR A C 1 ATOM 3155 O O . TYR A 1 386 ? 50.491 31.357 16.880 1.00 32.92 ? 422 TYR A O 1 ATOM 3156 C CB . TYR A 1 386 ? 50.210 32.795 14.228 1.00 30.18 ? 422 TYR A CB 1 ATOM 3157 C CG . TYR A 1 386 ? 51.224 32.142 13.327 1.00 35.93 ? 422 TYR A CG 1 ATOM 3158 C CD1 . TYR A 1 386 ? 50.826 31.397 12.217 1.00 42.36 ? 422 TYR A CD1 1 ATOM 3159 C CD2 . TYR A 1 386 ? 52.581 32.284 13.569 1.00 40.19 ? 422 TYR A CD2 1 ATOM 3160 C CE1 . TYR A 1 386 ? 51.761 30.806 11.382 1.00 45.89 ? 422 TYR A CE1 1 ATOM 3161 C CE2 . TYR A 1 386 ? 53.525 31.697 12.742 1.00 46.51 ? 422 TYR A CE2 1 ATOM 3162 C CZ . TYR A 1 386 ? 53.110 30.960 11.653 1.00 48.67 ? 422 TYR A CZ 1 ATOM 3163 O OH . TYR A 1 386 ? 54.054 30.382 10.839 1.00 53.44 ? 422 TYR A OH 1 ATOM 3164 N N . LYS A 1 387 ? 49.998 29.609 15.511 1.00 35.83 ? 423 LYS A N 1 ATOM 3165 C CA . LYS A 1 387 ? 50.693 28.575 16.279 1.00 31.61 ? 423 LYS A CA 1 ATOM 3166 C C . LYS A 1 387 ? 50.180 28.432 17.711 1.00 36.25 ? 423 LYS A C 1 ATOM 3167 O O . LYS A 1 387 ? 50.803 27.777 18.543 1.00 37.18 ? 423 LYS A O 1 ATOM 3168 C CB . LYS A 1 387 ? 52.213 28.797 16.266 1.00 36.78 ? 423 LYS A CB 1 ATOM 3169 C CG . LYS A 1 387 ? 52.872 28.547 14.903 1.00 43.47 ? 423 LYS A CG 1 ATOM 3170 C CD . LYS A 1 387 ? 54.352 28.909 14.916 1.00 50.19 ? 423 LYS A CD 1 ATOM 3171 C CE . LYS A 1 387 ? 55.013 28.659 13.565 1.00 61.55 ? 423 LYS A CE 1 ATOM 3172 N NZ . LYS A 1 387 ? 56.421 29.182 13.518 1.00 63.29 ? 423 LYS A NZ 1 ATOM 3173 N N . GLY A 1 388 ? 49.031 29.027 17.994 1.00 33.96 ? 424 GLY A N 1 ATOM 3174 C CA . GLY A 1 388 ? 48.442 28.902 19.311 1.00 37.05 ? 424 GLY A CA 1 ATOM 3175 C C . GLY A 1 388 ? 49.307 29.536 20.389 1.00 36.07 ? 424 GLY A C 1 ATOM 3176 O O . GLY A 1 388 ? 49.242 29.137 21.547 1.00 34.37 ? 424 GLY A O 1 ATOM 3177 N N . MET A 1 389 ? 50.111 30.524 20.007 1.00 30.89 ? 425 MET A N 1 ATOM 3178 C CA . MET A 1 389 ? 50.955 31.246 20.962 1.00 32.49 ? 425 MET A CA 1 ATOM 3179 C C . MET A 1 389 ? 50.262 32.531 21.421 1.00 32.57 ? 425 MET A C 1 ATOM 3180 O O . MET A 1 389 ? 50.170 33.496 20.658 1.00 32.30 ? 425 MET A O 1 ATOM 3181 C CB . MET A 1 389 ? 52.290 31.592 20.313 1.00 34.13 ? 425 MET A CB 1 ATOM 3182 C CG . MET A 1 389 ? 53.127 30.388 19.959 1.00 40.46 ? 425 MET A CG 1 ATOM 3183 S SD . MET A 1 389 ? 54.636 30.905 19.137 1.00 58.66 ? 425 MET A SD 1 ATOM 3184 C CE . MET A 1 389 ? 55.386 31.835 20.477 1.00 44.91 ? 425 MET A CE 1 ATOM 3185 N N . PRO A 1 390 ? 49.749 32.546 22.661 1.00 30.14 ? 426 PRO A N 1 ATOM 3186 C CA . PRO A 1 390 ? 48.977 33.714 23.111 1.00 27.54 ? 426 PRO A CA 1 ATOM 3187 C C . PRO A 1 390 ? 49.801 34.997 23.189 1.00 28.99 ? 426 PRO A C 1 ATOM 3188 O O . PRO A 1 390 ? 49.234 36.086 23.195 1.00 29.10 ? 426 PRO A O 1 ATOM 3189 C CB . PRO A 1 390 ? 48.469 33.300 24.500 1.00 33.23 ? 426 PRO A CB 1 ATOM 3190 C CG . PRO A 1 390 ? 49.262 32.092 24.891 1.00 33.32 ? 426 PRO A CG 1 ATOM 3191 C CD . PRO A 1 390 ? 49.715 31.434 23.626 1.00 29.19 ? 426 PRO A CD 1 ATOM 3192 N N . GLY A 1 391 ? 51.122 34.865 23.236 1.00 31.21 ? 427 GLY A N 1 ATOM 3193 C CA . GLY A 1 391 ? 52.017 36.009 23.287 1.00 30.80 ? 427 GLY A CA 1 ATOM 3194 C C . GLY A 1 391 ? 52.583 36.457 21.943 1.00 30.93 ? 427 GLY A C 1 ATOM 3195 O O . GLY A 1 391 ? 53.493 37.282 21.889 1.00 33.29 ? 427 GLY A O 1 ATOM 3196 N N . GLY A 1 392 ? 52.053 35.915 20.853 1.00 28.51 ? 428 GLY A N 1 ATOM 3197 C CA . GLY A 1 392 ? 52.410 36.390 19.522 1.00 28.91 ? 428 GLY A CA 1 ATOM 3198 C C . GLY A 1 392 ? 51.262 37.234 19.006 1.00 29.28 ? 428 GLY A C 1 ATOM 3199 O O . GLY A 1 392 ? 50.151 37.096 19.500 1.00 28.37 ? 428 GLY A O 1 ATOM 3200 N N . ARG A 1 393 ? 51.531 38.103 18.030 1.00 30.08 ? 429 ARG A N 1 ATOM 3201 C CA . ARG A 1 393 ? 50.509 38.930 17.388 1.00 27.65 ? 429 ARG A CA 1 ATOM 3202 C C . ARG A 1 393 ? 50.699 38.925 15.867 1.00 29.76 ? 429 ARG A C 1 ATOM 3203 O O . ARG A 1 393 ? 51.799 39.175 15.383 1.00 28.45 ? 429 ARG A O 1 ATOM 3204 C CB . ARG A 1 393 ? 50.609 40.373 17.879 1.00 28.42 ? 429 ARG A CB 1 ATOM 3205 C CG . ARG A 1 393 ? 50.567 40.552 19.409 1.00 32.04 ? 429 ARG A CG 1 ATOM 3206 C CD . ARG A 1 393 ? 49.174 40.889 19.875 1.00 34.94 ? 429 ARG A CD 1 ATOM 3207 N NE . ARG A 1 393 ? 49.059 41.094 21.322 1.00 31.46 ? 429 ARG A NE 1 ATOM 3208 C CZ . ARG A 1 393 ? 49.020 42.289 21.923 1.00 41.93 ? 429 ARG A CZ 1 ATOM 3209 N NH1 . ARG A 1 393 ? 49.109 43.420 21.207 1.00 29.28 ? 429 ARG A NH1 1 ATOM 3210 N NH2 . ARG A 1 393 ? 48.894 42.354 23.255 1.00 39.98 ? 429 ARG A NH2 1 ATOM 3211 N N . ASN A 1 394 ? 49.637 38.655 15.113 1.00 27.83 ? 430 ASN A N 1 ATOM 3212 C CA . ASN A 1 394 ? 49.700 38.759 13.651 1.00 27.05 ? 430 ASN A CA 1 ATOM 3213 C C . ASN A 1 394 ? 48.495 39.459 13.048 1.00 27.56 ? 430 ASN A C 1 ATOM 3214 O O . ASN A 1 394 ? 47.406 39.426 13.617 1.00 26.17 ? 430 ASN A O 1 ATOM 3215 C CB . ASN A 1 394 ? 49.849 37.390 12.984 1.00 26.46 ? 430 ASN A CB 1 ATOM 3216 C CG . ASN A 1 394 ? 51.234 36.834 13.127 1.00 30.21 ? 430 ASN A CG 1 ATOM 3217 O OD1 . ASN A 1 394 ? 51.463 35.936 13.923 1.00 33.00 ? 430 ASN A OD1 1 ATOM 3218 N ND2 . ASN A 1 394 ? 52.174 37.381 12.376 1.00 26.76 ? 430 ASN A ND2 1 ATOM 3219 N N . LEU A 1 395 ? 48.710 40.076 11.886 1.00 25.63 ? 431 LEU A N 1 ATOM 3220 C CA . LEU A 1 395 ? 47.655 40.742 11.131 1.00 26.33 ? 431 LEU A CA 1 ATOM 3221 C C . LEU A 1 395 ? 46.943 39.754 10.227 1.00 27.48 ? 431 LEU A C 1 ATOM 3222 O O . LEU A 1 395 ? 47.593 39.045 9.471 1.00 27.05 ? 431 LEU A O 1 ATOM 3223 C CB . LEU A 1 395 ? 48.256 41.839 10.263 1.00 22.04 ? 431 LEU A CB 1 ATOM 3224 C CG . LEU A 1 395 ? 47.273 42.645 9.432 1.00 25.04 ? 431 LEU A CG 1 ATOM 3225 C CD1 . LEU A 1 395 ? 46.310 43.393 10.324 1.00 27.64 ? 431 LEU A CD1 1 ATOM 3226 C CD2 . LEU A 1 395 ? 48.035 43.626 8.550 1.00 26.94 ? 431 LEU A CD2 1 ATOM 3227 N N . TYR A 1 396 ? 45.614 39.745 10.296 1.00 28.52 ? 432 TYR A N 1 ATOM 3228 C CA . TYR A 1 396 ? 44.761 38.970 9.403 1.00 27.72 ? 432 TYR A CA 1 ATOM 3229 C C . TYR A 1 396 ? 43.762 39.883 8.691 1.00 30.37 ? 432 TYR A C 1 ATOM 3230 O O . TYR A 1 396 ? 43.509 41.011 9.136 1.00 30.75 ? 432 TYR A O 1 ATOM 3231 C CB . TYR A 1 396 ? 43.982 37.922 10.199 1.00 28.65 ? 432 TYR A CB 1 ATOM 3232 C CG . TYR A 1 396 ? 44.854 36.910 10.872 1.00 29.36 ? 432 TYR A CG 1 ATOM 3233 C CD1 . TYR A 1 396 ? 45.484 37.205 12.076 1.00 27.09 ? 432 TYR A CD1 1 ATOM 3234 C CD2 . TYR A 1 396 ? 45.064 35.657 10.306 1.00 29.16 ? 432 TYR A CD2 1 ATOM 3235 C CE1 . TYR A 1 396 ? 46.295 36.285 12.698 1.00 26.73 ? 432 TYR A CE1 1 ATOM 3236 C CE2 . TYR A 1 396 ? 45.866 34.725 10.926 1.00 27.45 ? 432 TYR A CE2 1 ATOM 3237 C CZ . TYR A 1 396 ? 46.484 35.048 12.123 1.00 31.73 ? 432 TYR A CZ 1 ATOM 3238 O OH . TYR A 1 396 ? 47.291 34.137 12.758 1.00 31.31 ? 432 TYR A OH 1 ATOM 3239 N N . LYS A 1 397 ? 43.207 39.394 7.582 1.00 27.44 ? 433 LYS A N 1 ATOM 3240 C CA . LYS A 1 397 ? 42.043 40.008 6.968 1.00 26.54 ? 433 LYS A CA 1 ATOM 3241 C C . LYS A 1 397 ? 40.991 38.934 6.743 1.00 32.56 ? 433 LYS A C 1 ATOM 3242 O O . LYS A 1 397 ? 41.316 37.787 6.427 1.00 31.92 ? 433 LYS A O 1 ATOM 3243 C CB . LYS A 1 397 ? 42.396 40.714 5.662 1.00 25.52 ? 433 LYS A CB 1 ATOM 3244 C CG . LYS A 1 397 ? 42.703 39.793 4.484 1.00 30.53 ? 433 LYS A CG 1 ATOM 3245 C CD . LYS A 1 397 ? 43.096 40.610 3.226 1.00 28.11 ? 433 LYS A CD 1 ATOM 3246 C CE . LYS A 1 397 ? 43.294 39.696 2.007 1.00 32.59 ? 433 LYS A CE 1 ATOM 3247 N NZ . LYS A 1 397 ? 43.498 40.483 0.763 1.00 31.39 ? 433 LYS A NZ 1 ATOM 3248 N N . ILE A 1 398 ? 39.729 39.301 6.925 1.00 27.81 ? 434 ILE A N 1 ATOM 3249 C CA . ILE A 1 398 ? 38.637 38.369 6.717 1.00 28.44 ? 434 ILE A CA 1 ATOM 3250 C C . ILE A 1 398 ? 37.706 38.905 5.636 1.00 32.61 ? 434 ILE A C 1 ATOM 3251 O O . ILE A 1 398 ? 37.305 40.067 5.672 1.00 31.14 ? 434 ILE A O 1 ATOM 3252 C CB . ILE A 1 398 ? 37.885 38.069 8.029 1.00 34.14 ? 434 ILE A CB 1 ATOM 3253 C CG1 . ILE A 1 398 ? 36.620 37.263 7.748 1.00 35.26 ? 434 ILE A CG1 1 ATOM 3254 C CG2 . ILE A 1 398 ? 37.526 39.345 8.767 1.00 31.49 ? 434 ILE A CG2 1 ATOM 3255 C CD1 . ILE A 1 398 ? 36.053 36.628 8.998 1.00 36.57 ? 434 ILE A CD1 1 ATOM 3256 N N . GLN A 1 399 ? 37.403 38.065 4.650 1.00 27.94 ? 435 GLN A N 1 ATOM 3257 C CA . GLN A 1 399 ? 36.589 38.473 3.509 1.00 29.98 ? 435 GLN A CA 1 ATOM 3258 C C . GLN A 1 399 ? 35.143 38.646 3.942 1.00 30.16 ? 435 GLN A C 1 ATOM 3259 O O . GLN A 1 399 ? 34.500 37.689 4.370 1.00 27.54 ? 435 GLN A O 1 ATOM 3260 C CB . GLN A 1 399 ? 36.684 37.414 2.402 1.00 31.08 ? 435 GLN A CB 1 ATOM 3261 C CG . GLN A 1 399 ? 35.907 37.747 1.149 1.00 29.27 ? 435 GLN A CG 1 ATOM 3262 C CD . GLN A 1 399 ? 36.059 36.668 0.072 1.00 37.41 ? 435 GLN A CD 1 ATOM 3263 O OE1 . GLN A 1 399 ? 37.157 36.164 -0.174 1.00 30.87 ? 435 GLN A OE1 1 ATOM 3264 N NE2 . GLN A 1 399 ? 34.951 36.308 -0.563 1.00 32.32 ? 435 GLN A NE2 1 ATOM 3265 N N . LEU A 1 400 ? 34.625 39.867 3.837 1.00 28.14 ? 436 LEU A N 1 ATOM 3266 C CA . LEU A 1 400 ? 33.285 40.143 4.349 1.00 31.68 ? 436 LEU A CA 1 ATOM 3267 C C . LEU A 1 400 ? 32.168 39.347 3.643 1.00 33.15 ? 436 LEU A C 1 ATOM 3268 O O . LEU A 1 400 ? 31.104 39.123 4.216 1.00 33.96 ? 436 LEU A O 1 ATOM 3269 C CB . LEU A 1 400 ? 33.002 41.642 4.319 1.00 32.65 ? 436 LEU A CB 1 ATOM 3270 C CG . LEU A 1 400 ? 33.853 42.459 5.297 1.00 31.40 ? 436 LEU A CG 1 ATOM 3271 C CD1 . LEU A 1 400 ? 33.332 43.888 5.375 1.00 34.05 ? 436 LEU A CD1 1 ATOM 3272 C CD2 . LEU A 1 400 ? 33.834 41.838 6.664 1.00 27.43 ? 436 LEU A CD2 1 ATOM 3273 N N . SER A 1 401 ? 32.412 38.904 2.413 1.00 30.36 ? 437 SER A N 1 ATOM 3274 C CA . SER A 1 401 ? 31.389 38.152 1.679 1.00 32.37 ? 437 SER A CA 1 ATOM 3275 C C . SER A 1 401 ? 31.481 36.636 1.911 1.00 33.12 ? 437 SER A C 1 ATOM 3276 O O . SER A 1 401 ? 30.649 35.865 1.418 1.00 35.23 ? 437 SER A O 1 ATOM 3277 C CB . SER A 1 401 ? 31.459 38.476 0.184 1.00 31.66 ? 437 SER A CB 1 ATOM 3278 O OG . SER A 1 401 ? 32.655 37.958 -0.368 1.00 29.72 ? 437 SER A OG 1 ATOM 3279 N N . ASP A 1 402 ? 32.489 36.207 2.663 1.00 30.12 ? 438 ASP A N 1 ATOM 3280 C CA . ASP A 1 402 ? 32.647 34.794 3.011 1.00 32.49 ? 438 ASP A CA 1 ATOM 3281 C C . ASP A 1 402 ? 33.563 34.666 4.219 1.00 33.75 ? 438 ASP A C 1 ATOM 3282 O O . ASP A 1 402 ? 34.781 34.592 4.083 1.00 33.84 ? 438 ASP A O 1 ATOM 3283 C CB . ASP A 1 402 ? 33.219 33.989 1.830 1.00 34.67 ? 438 ASP A CB 1 ATOM 3284 C CG . ASP A 1 402 ? 33.352 32.500 2.148 1.00 42.02 ? 438 ASP A CG 1 ATOM 3285 O OD1 . ASP A 1 402 ? 33.312 32.133 3.351 1.00 40.27 ? 438 ASP A OD1 1 ATOM 3286 O OD2 . ASP A 1 402 ? 33.506 31.697 1.196 1.00 42.24 ? 438 ASP A OD2 1 ATOM 3287 N N . TYR A 1 403 ? 32.964 34.621 5.402 1.00 34.90 ? 439 TYR A N 1 ATOM 3288 C CA . TYR A 1 403 ? 33.707 34.688 6.648 1.00 34.41 ? 439 TYR A CA 1 ATOM 3289 C C . TYR A 1 403 ? 34.753 33.583 6.786 1.00 38.24 ? 439 TYR A C 1 ATOM 3290 O O . TYR A 1 403 ? 35.686 33.695 7.593 1.00 34.48 ? 439 TYR A O 1 ATOM 3291 C CB . TYR A 1 403 ? 32.739 34.656 7.832 1.00 33.88 ? 439 TYR A CB 1 ATOM 3292 C CG . TYR A 1 403 ? 31.808 35.846 7.889 1.00 31.92 ? 439 TYR A CG 1 ATOM 3293 C CD1 . TYR A 1 403 ? 32.201 37.093 7.395 1.00 30.53 ? 439 TYR A CD1 1 ATOM 3294 C CD2 . TYR A 1 403 ? 30.537 35.728 8.441 1.00 33.91 ? 439 TYR A CD2 1 ATOM 3295 C CE1 . TYR A 1 403 ? 31.344 38.193 7.450 1.00 31.43 ? 439 TYR A CE1 1 ATOM 3296 C CE2 . TYR A 1 403 ? 29.675 36.818 8.503 1.00 36.59 ? 439 TYR A CE2 1 ATOM 3297 C CZ . TYR A 1 403 ? 30.081 38.046 8.010 1.00 35.00 ? 439 TYR A CZ 1 ATOM 3298 O OH . TYR A 1 403 ? 29.210 39.117 8.077 1.00 35.17 ? 439 TYR A OH 1 ATOM 3299 N N . THR A 1 404 ? 34.613 32.519 6.000 1.00 37.01 ? 440 THR A N 1 ATOM 3300 C CA . THR A 1 404 ? 35.528 31.393 6.134 1.00 34.82 ? 440 THR A CA 1 ATOM 3301 C C . THR A 1 404 ? 36.837 31.653 5.403 1.00 30.06 ? 440 THR A C 1 ATOM 3302 O O . THR A 1 404 ? 37.784 30.883 5.511 1.00 34.94 ? 440 THR A O 1 ATOM 3303 C CB . THR A 1 404 ? 34.911 30.088 5.620 1.00 37.92 ? 440 THR A CB 1 ATOM 3304 O OG1 . THR A 1 404 ? 34.878 30.122 4.191 1.00 37.73 ? 440 THR A OG1 1 ATOM 3305 C CG2 . THR A 1 404 ? 33.498 29.920 6.163 1.00 40.02 ? 440 THR A CG2 1 ATOM 3306 N N . LYS A 1 405 ? 36.895 32.731 4.642 1.00 32.25 ? 441 LYS A N 1 ATOM 3307 C CA . LYS A 1 405 ? 38.131 33.046 3.960 1.00 30.08 ? 441 LYS A CA 1 ATOM 3308 C C . LYS A 1 405 ? 38.922 34.070 4.767 1.00 32.60 ? 441 LYS A C 1 ATOM 3309 O O . LYS A 1 405 ? 38.704 35.275 4.658 1.00 31.36 ? 441 LYS A O 1 ATOM 3310 C CB . LYS A 1 405 ? 37.871 33.513 2.534 1.00 35.29 ? 441 LYS A CB 1 ATOM 3311 C CG . LYS A 1 405 ? 37.317 32.398 1.636 1.00 36.02 ? 441 LYS A CG 1 ATOM 3312 C CD . LYS A 1 405 ? 37.248 32.846 0.186 1.00 33.73 ? 441 LYS A CD 1 ATOM 3313 N N . VAL A 1 406 ? 39.838 33.557 5.582 1.00 31.14 ? 442 VAL A N 1 ATOM 3314 C CA . VAL A 1 406 ? 40.662 34.382 6.453 1.00 32.63 ? 442 VAL A CA 1 ATOM 3315 C C . VAL A 1 406 ? 42.096 34.228 6.019 1.00 32.58 ? 442 VAL A C 1 ATOM 3316 O O . VAL A 1 406 ? 42.594 33.115 5.895 1.00 32.84 ? 442 VAL A O 1 ATOM 3317 C CB . VAL A 1 406 ? 40.523 33.951 7.915 1.00 31.83 ? 442 VAL A CB 1 ATOM 3318 C CG1 . VAL A 1 406 ? 41.456 34.772 8.815 1.00 34.38 ? 442 VAL A CG1 1 ATOM 3319 C CG2 . VAL A 1 406 ? 39.089 34.110 8.360 1.00 30.38 ? 442 VAL A CG2 1 ATOM 3320 N N . THR A 1 407 ? 42.748 35.350 5.755 1.00 31.26 ? 443 THR A N 1 ATOM 3321 C CA . THR A 1 407 ? 44.109 35.329 5.247 1.00 31.21 ? 443 THR A CA 1 ATOM 3322 C C . THR A 1 407 ? 45.057 35.975 6.250 1.00 33.00 ? 443 THR A C 1 ATOM 3323 O O . THR A 1 407 ? 44.822 37.095 6.691 1.00 30.05 ? 443 THR A O 1 ATOM 3324 C CB . THR A 1 407 ? 44.209 36.090 3.913 1.00 32.60 ? 443 THR A CB 1 ATOM 3325 O OG1 . THR A 1 407 ? 43.318 35.499 2.955 1.00 34.80 ? 443 THR A OG1 1 ATOM 3326 C CG2 . THR A 1 407 ? 45.630 36.033 3.367 1.00 34.50 ? 443 THR A CG2 1 ATOM 3327 N N . CYS A 1 408 ? 46.118 35.270 6.617 1.00 29.35 ? 444 CYS A N 1 ATOM 3328 C CA . CYS A 1 408 ? 47.150 35.880 7.438 1.00 31.96 ? 444 CYS A CA 1 ATOM 3329 C C . CYS A 1 408 ? 48.070 36.724 6.577 1.00 34.29 ? 444 CYS A C 1 ATOM 3330 O O . CYS A 1 408 ? 48.619 36.254 5.595 1.00 32.29 ? 444 CYS A O 1 ATOM 3331 C CB . CYS A 1 408 ? 47.954 34.836 8.200 1.00 34.69 ? 444 CYS A CB 1 ATOM 3332 S SG . CYS A 1 408 ? 48.936 35.584 9.563 1.00 38.61 ? 444 CYS A SG 1 ATOM 3333 N N . LEU A 1 409 ? 48.236 37.982 6.956 1.00 32.20 ? 445 LEU A N 1 ATOM 3334 C CA . LEU A 1 409 ? 49.013 38.922 6.164 1.00 29.23 ? 445 LEU A CA 1 ATOM 3335 C C . LEU A 1 409 ? 50.480 39.075 6.614 1.00 32.67 ? 445 LEU A C 1 ATOM 3336 O O . LEU A 1 409 ? 51.309 39.605 5.872 1.00 30.42 ? 445 LEU A O 1 ATOM 3337 C CB . LEU A 1 409 ? 48.325 40.288 6.180 1.00 27.64 ? 445 LEU A CB 1 ATOM 3338 C CG . LEU A 1 409 ? 46.892 40.276 5.659 1.00 30.32 ? 445 LEU A CG 1 ATOM 3339 C CD1 . LEU A 1 409 ? 46.367 41.697 5.573 1.00 29.83 ? 445 LEU A CD1 1 ATOM 3340 C CD2 . LEU A 1 409 ? 46.852 39.613 4.284 1.00 29.16 ? 445 LEU A CD2 1 ATOM 3341 N N . SER A 1 410 ? 50.802 38.615 7.817 1.00 29.36 ? 446 SER A N 1 ATOM 3342 C CA . SER A 1 410 ? 52.114 38.890 8.405 1.00 29.03 ? 446 SER A CA 1 ATOM 3343 C C . SER A 1 410 ? 52.823 37.628 8.886 1.00 30.80 ? 446 SER A C 1 ATOM 3344 O O . SER A 1 410 ? 54.022 37.641 9.151 1.00 32.64 ? 446 SER A O 1 ATOM 3345 C CB . SER A 1 410 ? 51.944 39.838 9.593 1.00 27.69 ? 446 SER A CB 1 ATOM 3346 O OG . SER A 1 410 ? 51.194 39.190 10.617 1.00 29.58 ? 446 SER A OG 1 ATOM 3347 N N . CYS A 1 411 ? 52.078 36.540 9.013 1.00 32.89 ? 447 CYS A N 1 ATOM 3348 C CA . CYS A 1 411 ? 52.597 35.329 9.625 1.00 36.21 ? 447 CYS A CA 1 ATOM 3349 C C . CYS A 1 411 ? 53.876 34.822 8.973 1.00 42.02 ? 447 CYS A C 1 ATOM 3350 O O . CYS A 1 411 ? 54.821 34.433 9.666 1.00 41.52 ? 447 CYS A O 1 ATOM 3351 C CB . CYS A 1 411 ? 51.534 34.225 9.614 1.00 42.24 ? 447 CYS A CB 1 ATOM 3352 S SG . CYS A 1 411 ? 50.166 34.517 10.791 1.00 51.76 ? 447 CYS A SG 1 ATOM 3353 N N . GLU A 1 412 ? 53.912 34.812 7.646 1.00 36.77 ? 448 GLU A N 1 ATOM 3354 C CA . GLU A 1 412 ? 55.046 34.194 6.956 1.00 40.71 ? 448 GLU A CA 1 ATOM 3355 C C . GLU A 1 412 ? 56.044 35.183 6.353 1.00 39.05 ? 448 GLU A C 1 ATOM 3356 O O . GLU A 1 412 ? 56.934 34.790 5.600 1.00 38.79 ? 448 GLU A O 1 ATOM 3357 C CB . GLU A 1 412 ? 54.552 33.201 5.900 1.00 41.53 ? 448 GLU A CB 1 ATOM 3358 C CG . GLU A 1 412 ? 53.565 32.180 6.453 1.00 43.85 ? 448 GLU A CG 1 ATOM 3359 C CD . GLU A 1 412 ? 54.200 31.237 7.466 1.00 52.90 ? 448 GLU A CD 1 ATOM 3360 O OE1 . GLU A 1 412 ? 55.420 30.954 7.345 1.00 52.38 ? 448 GLU A OE1 1 ATOM 3361 O OE2 . GLU A 1 412 ? 53.477 30.774 8.384 1.00 55.98 ? 448 GLU A OE2 1 ATOM 3362 N N . LEU A 1 413 ? 55.922 36.460 6.700 1.00 35.88 ? 449 LEU A N 1 ATOM 3363 C CA . LEU A 1 413 ? 56.844 37.456 6.161 1.00 37.19 ? 449 LEU A CA 1 ATOM 3364 C C . LEU A 1 413 ? 58.292 37.173 6.573 1.00 39.71 ? 449 LEU A C 1 ATOM 3365 O O . LEU A 1 413 ? 59.202 37.228 5.745 1.00 35.68 ? 449 LEU A O 1 ATOM 3366 C CB . LEU A 1 413 ? 56.422 38.866 6.573 1.00 34.86 ? 449 LEU A CB 1 ATOM 3367 C CG . LEU A 1 413 ? 55.080 39.277 5.976 1.00 34.54 ? 449 LEU A CG 1 ATOM 3368 C CD1 . LEU A 1 413 ? 54.691 40.654 6.462 1.00 34.37 ? 449 LEU A CD1 1 ATOM 3369 C CD2 . LEU A 1 413 ? 55.167 39.243 4.452 1.00 38.63 ? 449 LEU A CD2 1 ATOM 3370 N N . ASN A 1 414 ? 58.502 36.892 7.859 1.00 36.61 ? 450 ASN A N 1 ATOM 3371 C CA . ASN A 1 414 ? 59.792 36.414 8.358 1.00 37.02 ? 450 ASN A CA 1 ATOM 3372 C C . ASN A 1 414 ? 59.553 35.704 9.679 1.00 38.72 ? 450 ASN A C 1 ATOM 3373 O O . ASN A 1 414 ? 59.663 36.304 10.753 1.00 33.58 ? 450 ASN A O 1 ATOM 3374 C CB . ASN A 1 414 ? 60.819 37.538 8.517 1.00 36.37 ? 450 ASN A CB 1 ATOM 3375 C CG . ASN A 1 414 ? 62.266 37.003 8.752 1.00 49.59 ? 450 ASN A CG 1 ATOM 3376 O OD1 . ASN A 1 414 ? 62.480 35.889 9.279 1.00 43.84 ? 450 ASN A OD1 1 ATOM 3377 N ND2 . ASN A 1 414 ? 63.258 37.808 8.360 1.00 45.72 ? 450 ASN A ND2 1 ATOM 3378 N N . PRO A 1 415 ? 59.197 34.421 9.593 1.00 36.87 ? 451 PRO A N 1 ATOM 3379 C CA . PRO A 1 415 ? 58.686 33.628 10.712 1.00 40.50 ? 451 PRO A CA 1 ATOM 3380 C C . PRO A 1 415 ? 59.639 33.530 11.899 1.00 38.76 ? 451 PRO A C 1 ATOM 3381 O O . PRO A 1 415 ? 59.181 33.376 13.024 1.00 39.93 ? 451 PRO A O 1 ATOM 3382 C CB . PRO A 1 415 ? 58.451 32.248 10.087 1.00 40.60 ? 451 PRO A CB 1 ATOM 3383 C CG . PRO A 1 415 ? 59.287 32.240 8.852 1.00 41.41 ? 451 PRO A CG 1 ATOM 3384 C CD . PRO A 1 415 ? 59.282 33.635 8.350 1.00 38.15 ? 451 PRO A CD 1 ATOM 3385 N N . GLU A 1 416 ? 60.940 33.627 11.673 1.00 41.00 ? 452 GLU A N 1 ATOM 3386 C CA . GLU A 1 416 ? 61.861 33.448 12.793 1.00 41.63 ? 452 GLU A CA 1 ATOM 3387 C C . GLU A 1 416 ? 62.168 34.772 13.495 1.00 39.48 ? 452 GLU A C 1 ATOM 3388 O O . GLU A 1 416 ? 62.292 34.817 14.717 1.00 42.32 ? 452 GLU A O 1 ATOM 3389 C CB . GLU A 1 416 ? 63.145 32.750 12.344 1.00 47.71 ? 452 GLU A CB 1 ATOM 3390 C CG . GLU A 1 416 ? 62.905 31.666 11.294 1.00 59.72 ? 452 GLU A CG 1 ATOM 3391 C CD . GLU A 1 416 ? 63.652 30.378 11.594 1.00 76.98 ? 452 GLU A CD 1 ATOM 3392 O OE1 . GLU A 1 416 ? 64.783 30.210 11.076 1.00 75.28 ? 452 GLU A OE1 1 ATOM 3393 O OE2 . GLU A 1 416 ? 63.100 29.534 12.342 1.00 76.30 ? 452 GLU A OE2 1 ATOM 3394 N N . ARG A 1 417 ? 62.261 35.850 12.726 1.00 33.85 ? 453 ARG A N 1 ATOM 3395 C CA . ARG A 1 417 ? 62.547 37.157 13.308 1.00 33.53 ? 453 ARG A CA 1 ATOM 3396 C C . ARG A 1 417 ? 61.294 37.875 13.827 1.00 34.76 ? 453 ARG A C 1 ATOM 3397 O O . ARG A 1 417 ? 61.364 38.639 14.785 1.00 32.24 ? 453 ARG A O 1 ATOM 3398 C CB . ARG A 1 417 ? 63.256 38.035 12.283 1.00 34.18 ? 453 ARG A CB 1 ATOM 3399 C CG . ARG A 1 417 ? 63.284 39.493 12.636 1.00 31.62 ? 453 ARG A CG 1 ATOM 3400 C CD . ARG A 1 417 ? 64.073 40.262 11.604 1.00 30.45 ? 453 ARG A CD 1 ATOM 3401 N NE . ARG A 1 417 ? 64.233 41.655 11.991 1.00 28.05 ? 453 ARG A NE 1 ATOM 3402 C CZ . ARG A 1 417 ? 65.015 42.513 11.352 1.00 32.88 ? 453 ARG A CZ 1 ATOM 3403 N NH1 . ARG A 1 417 ? 65.717 42.116 10.295 1.00 32.28 ? 453 ARG A NH1 1 ATOM 3404 N NH2 . ARG A 1 417 ? 65.095 43.765 11.764 1.00 29.63 ? 453 ARG A NH2 1 ATOM 3405 N N . CYS A 1 418 ? 60.146 37.627 13.208 1.00 32.84 ? 454 CYS A N 1 ATOM 3406 C CA . CYS A 1 418 ? 58.968 38.440 13.483 1.00 28.79 ? 454 CYS A CA 1 ATOM 3407 C C . CYS A 1 418 ? 57.733 37.634 13.858 1.00 34.96 ? 454 CYS A C 1 ATOM 3408 O O . CYS A 1 418 ? 57.159 36.913 13.019 1.00 30.28 ? 454 CYS A O 1 ATOM 3409 C CB . CYS A 1 418 ? 58.659 39.305 12.266 1.00 32.65 ? 454 CYS A CB 1 ATOM 3410 S SG . CYS A 1 418 ? 59.871 40.597 12.000 1.00 35.21 ? 454 CYS A SG 1 ATOM 3411 N N . GLN A 1 419 ? 57.304 37.786 15.112 1.00 31.36 ? 455 GLN A N 1 ATOM 3412 C CA . GLN A 1 419 ? 56.129 37.081 15.603 1.00 31.93 ? 455 GLN A CA 1 ATOM 3413 C C . GLN A 1 419 ? 55.176 37.981 16.378 1.00 29.94 ? 455 GLN A C 1 ATOM 3414 O O . GLN A 1 419 ? 54.210 37.498 16.935 1.00 30.25 ? 455 GLN A O 1 ATOM 3415 C CB . GLN A 1 419 ? 56.540 35.894 16.478 1.00 30.15 ? 455 GLN A CB 1 ATOM 3416 C CG . GLN A 1 419 ? 57.190 34.754 15.706 1.00 33.81 ? 455 GLN A CG 1 ATOM 3417 C CD . GLN A 1 419 ? 58.079 33.902 16.583 1.00 40.76 ? 455 GLN A CD 1 ATOM 3418 O OE1 . GLN A 1 419 ? 57.878 33.824 17.798 1.00 40.64 ? 455 GLN A OE1 1 ATOM 3419 N NE2 . GLN A 1 419 ? 59.090 33.277 15.980 1.00 40.46 ? 455 GLN A NE2 1 ATOM 3420 N N . TYR A 1 420 ? 55.444 39.282 16.407 1.00 28.84 ? 456 TYR A N 1 ATOM 3421 C CA . TYR A 1 420 ? 54.631 40.216 17.189 1.00 28.64 ? 456 TYR A CA 1 ATOM 3422 C C . TYR A 1 420 ? 54.472 41.490 16.368 1.00 30.27 ? 456 TYR A C 1 ATOM 3423 O O . TYR A 1 420 ? 55.396 42.299 16.298 1.00 31.11 ? 456 TYR A O 1 ATOM 3424 C CB . TYR A 1 420 ? 55.342 40.538 18.519 1.00 28.33 ? 456 TYR A CB 1 ATOM 3425 C CG . TYR A 1 420 ? 54.457 41.059 19.648 1.00 26.19 ? 456 TYR A CG 1 ATOM 3426 C CD1 . TYR A 1 420 ? 54.118 42.401 19.730 1.00 27.45 ? 456 TYR A CD1 1 ATOM 3427 C CD2 . TYR A 1 420 ? 53.989 40.205 20.642 1.00 25.47 ? 456 TYR A CD2 1 ATOM 3428 C CE1 . TYR A 1 420 ? 53.317 42.881 20.761 1.00 25.06 ? 456 TYR A CE1 1 ATOM 3429 C CE2 . TYR A 1 420 ? 53.178 40.681 21.691 1.00 28.20 ? 456 TYR A CE2 1 ATOM 3430 C CZ . TYR A 1 420 ? 52.853 42.019 21.738 1.00 28.45 ? 456 TYR A CZ 1 ATOM 3431 O OH . TYR A 1 420 ? 52.057 42.513 22.759 1.00 32.01 ? 456 TYR A OH 1 ATOM 3432 N N . TYR A 1 421 ? 53.311 41.666 15.741 1.00 28.23 ? 457 TYR A N 1 ATOM 3433 C CA . TYR A 1 421 ? 53.083 42.808 14.862 1.00 26.08 ? 457 TYR A CA 1 ATOM 3434 C C . TYR A 1 421 ? 52.023 43.750 15.379 1.00 27.54 ? 457 TYR A C 1 ATOM 3435 O O . TYR A 1 421 ? 51.067 43.322 16.005 1.00 26.18 ? 457 TYR A O 1 ATOM 3436 C CB . TYR A 1 421 ? 52.578 42.342 13.500 1.00 25.75 ? 457 TYR A CB 1 ATOM 3437 C CG . TYR A 1 421 ? 53.602 41.686 12.615 1.00 25.45 ? 457 TYR A CG 1 ATOM 3438 C CD1 . TYR A 1 421 ? 54.329 42.435 11.702 1.00 28.60 ? 457 TYR A CD1 1 ATOM 3439 C CD2 . TYR A 1 421 ? 53.819 40.318 12.672 1.00 29.82 ? 457 TYR A CD2 1 ATOM 3440 C CE1 . TYR A 1 421 ? 55.250 41.849 10.863 1.00 30.32 ? 457 TYR A CE1 1 ATOM 3441 C CE2 . TYR A 1 421 ? 54.739 39.715 11.842 1.00 28.57 ? 457 TYR A CE2 1 ATOM 3442 C CZ . TYR A 1 421 ? 55.451 40.489 10.932 1.00 29.03 ? 457 TYR A CZ 1 ATOM 3443 O OH . TYR A 1 421 ? 56.377 39.912 10.092 1.00 25.75 ? 457 TYR A OH 1 ATOM 3444 N N . SER A 1 422 ? 52.195 45.027 15.060 1.00 25.86 ? 458 SER A N 1 ATOM 3445 C CA . SER A 1 422 ? 51.130 46.011 15.136 1.00 29.67 ? 458 SER A CA 1 ATOM 3446 C C . SER A 1 422 ? 51.085 46.633 13.750 1.00 29.20 ? 458 SER A C 1 ATOM 3447 O O . SER A 1 422 ? 51.975 46.383 12.927 1.00 25.99 ? 458 SER A O 1 ATOM 3448 C CB . SER A 1 422 ? 51.417 47.070 16.214 1.00 31.70 ? 458 SER A CB 1 ATOM 3449 O OG . SER A 1 422 ? 52.540 47.871 15.883 1.00 32.14 ? 458 SER A OG 1 ATOM 3450 N N . VAL A 1 423 ? 50.063 47.438 13.478 1.00 29.26 ? 459 VAL A N 1 ATOM 3451 C CA . VAL A 1 423 ? 49.854 47.936 12.115 1.00 25.78 ? 459 VAL A CA 1 ATOM 3452 C C . VAL A 1 423 ? 49.279 49.347 12.135 1.00 28.99 ? 459 VAL A C 1 ATOM 3453 O O . VAL A 1 423 ? 48.620 49.752 13.104 1.00 26.18 ? 459 VAL A O 1 ATOM 3454 C CB . VAL A 1 423 ? 48.907 46.985 11.338 1.00 28.04 ? 459 VAL A CB 1 ATOM 3455 C CG1 . VAL A 1 423 ? 47.557 46.894 12.040 1.00 26.28 ? 459 VAL A CG1 1 ATOM 3456 C CG2 . VAL A 1 423 ? 48.734 47.420 9.887 1.00 25.90 ? 459 VAL A CG2 1 ATOM 3457 N N . SER A 1 424 ? 49.548 50.095 11.076 1.00 23.80 ? 460 SER A N 1 ATOM 3458 C CA . SER A 1 424 ? 48.974 51.414 10.884 1.00 22.00 ? 460 SER A CA 1 ATOM 3459 C C . SER A 1 424 ? 48.517 51.568 9.437 1.00 29.67 ? 460 SER A C 1 ATOM 3460 O O . SER A 1 424 ? 49.346 51.601 8.514 1.00 27.98 ? 460 SER A O 1 ATOM 3461 C CB . SER A 1 424 ? 50.023 52.464 11.202 1.00 30.76 ? 460 SER A CB 1 ATOM 3462 O OG . SER A 1 424 ? 49.577 53.738 10.823 1.00 29.47 ? 460 SER A OG 1 ATOM 3463 N N . PHE A 1 425 ? 47.206 51.653 9.232 1.00 26.01 ? 461 PHE A N 1 ATOM 3464 C CA . PHE A 1 425 ? 46.639 51.800 7.894 1.00 25.21 ? 461 PHE A CA 1 ATOM 3465 C C . PHE A 1 425 ? 46.495 53.258 7.479 1.00 27.94 ? 461 PHE A C 1 ATOM 3466 O O . PHE A 1 425 ? 46.205 54.125 8.308 1.00 26.70 ? 461 PHE A O 1 ATOM 3467 C CB . PHE A 1 425 ? 45.259 51.169 7.848 1.00 23.42 ? 461 PHE A CB 1 ATOM 3468 C CG . PHE A 1 425 ? 45.276 49.687 7.770 1.00 27.43 ? 461 PHE A CG 1 ATOM 3469 C CD1 . PHE A 1 425 ? 45.368 48.927 8.916 1.00 25.35 ? 461 PHE A CD1 1 ATOM 3470 C CD2 . PHE A 1 425 ? 45.161 49.042 6.549 1.00 26.23 ? 461 PHE A CD2 1 ATOM 3471 C CE1 . PHE A 1 425 ? 45.377 47.550 8.852 1.00 28.86 ? 461 PHE A CE1 1 ATOM 3472 C CE2 . PHE A 1 425 ? 45.165 47.660 6.481 1.00 27.23 ? 461 PHE A CE2 1 ATOM 3473 C CZ . PHE A 1 425 ? 45.274 46.917 7.639 1.00 25.53 ? 461 PHE A CZ 1 ATOM 3474 N N . SER A 1 426 ? 46.668 53.521 6.190 1.00 28.42 ? 462 SER A N 1 ATOM 3475 C CA . SER A 1 426 ? 46.390 54.832 5.603 1.00 29.70 ? 462 SER A CA 1 ATOM 3476 C C . SER A 1 426 ? 44.895 55.113 5.665 1.00 32.70 ? 462 SER A C 1 ATOM 3477 O O . SER A 1 426 ? 44.113 54.221 5.986 1.00 32.53 ? 462 SER A O 1 ATOM 3478 C CB . SER A 1 426 ? 46.827 54.862 4.139 1.00 29.47 ? 462 SER A CB 1 ATOM 3479 O OG . SER A 1 426 ? 45.965 54.062 3.339 1.00 31.62 ? 462 SER A OG 1 ATOM 3480 N N . LYS A 1 427 ? 44.496 56.341 5.335 1.00 33.88 ? 463 LYS A N 1 ATOM 3481 C CA . LYS A 1 427 ? 43.086 56.720 5.370 1.00 39.57 ? 463 LYS A CA 1 ATOM 3482 C C . LYS A 1 427 ? 42.367 55.916 4.292 1.00 44.24 ? 463 LYS A C 1 ATOM 3483 O O . LYS A 1 427 ? 42.784 55.924 3.148 1.00 46.39 ? 463 LYS A O 1 ATOM 3484 C CB . LYS A 1 427 ? 42.930 58.228 5.135 1.00 41.09 ? 463 LYS A CB 1 ATOM 3485 N N . GLU A 1 428 ? 41.309 55.201 4.655 1.00 46.37 ? 464 GLU A N 1 ATOM 3486 C CA . GLU A 1 428 ? 40.651 54.278 3.721 1.00 39.13 ? 464 GLU A CA 1 ATOM 3487 C C . GLU A 1 428 ? 41.442 52.997 3.455 1.00 37.38 ? 464 GLU A C 1 ATOM 3488 O O . GLU A 1 428 ? 41.045 52.181 2.627 1.00 32.86 ? 464 GLU A O 1 ATOM 3489 C CB . GLU A 1 428 ? 40.251 54.966 2.407 1.00 45.56 ? 464 GLU A CB 1 ATOM 3490 C CG . GLU A 1 428 ? 38.933 55.733 2.501 1.00 55.59 ? 464 GLU A CG 1 ATOM 3491 C CD . GLU A 1 428 ? 39.079 57.218 2.203 1.00 63.88 ? 464 GLU A CD 1 ATOM 3492 O OE1 . GLU A 1 428 ? 39.431 57.569 1.052 1.00 64.23 ? 464 GLU A OE1 1 ATOM 3493 O OE2 . GLU A 1 428 ? 38.835 58.035 3.124 1.00 68.19 ? 464 GLU A OE2 1 ATOM 3494 N N . ALA A 1 429 ? 42.552 52.811 4.165 1.00 33.62 ? 465 ALA A N 1 ATOM 3495 C CA . ALA A 1 429 ? 43.202 51.501 4.197 1.00 31.85 ? 465 ALA A CA 1 ATOM 3496 C C . ALA A 1 429 ? 43.777 51.004 2.865 1.00 35.21 ? 465 ALA A C 1 ATOM 3497 O O . ALA A 1 429 ? 43.837 49.789 2.623 1.00 30.50 ? 465 ALA A O 1 ATOM 3498 C CB . ALA A 1 429 ? 42.234 50.460 4.764 1.00 29.89 ? 465 ALA A CB 1 ATOM 3499 N N . LYS A 1 430 ? 44.209 51.923 2.007 1.00 31.04 ? 466 LYS A N 1 ATOM 3500 C CA . LYS A 1 430 ? 44.843 51.527 0.758 1.00 32.43 ? 466 LYS A CA 1 ATOM 3501 C C . LYS A 1 430 ? 46.265 50.988 0.993 1.00 33.07 ? 466 LYS A C 1 ATOM 3502 O O . LYS A 1 430 ? 46.757 50.158 0.232 1.00 30.04 ? 466 LYS A O 1 ATOM 3503 C CB . LYS A 1 430 ? 44.843 52.687 -0.246 1.00 35.14 ? 466 LYS A CB 1 ATOM 3504 N N . TYR A 1 431 ? 46.906 51.438 2.066 1.00 25.41 ? 467 TYR A N 1 ATOM 3505 C CA . TYR A 1 431 ? 48.263 51.011 2.392 1.00 27.79 ? 467 TYR A CA 1 ATOM 3506 C C . TYR A 1 431 ? 48.377 50.765 3.874 1.00 30.60 ? 467 TYR A C 1 ATOM 3507 O O . TYR A 1 431 ? 47.621 51.346 4.677 1.00 27.72 ? 467 TYR A O 1 ATOM 3508 C CB . TYR A 1 431 ? 49.305 52.066 1.979 1.00 31.87 ? 467 TYR A CB 1 ATOM 3509 C CG . TYR A 1 431 ? 49.240 52.399 0.525 1.00 29.58 ? 467 TYR A CG 1 ATOM 3510 C CD1 . TYR A 1 431 ? 49.835 51.573 -0.418 1.00 33.79 ? 467 TYR A CD1 1 ATOM 3511 C CD2 . TYR A 1 431 ? 48.549 53.513 0.084 1.00 29.17 ? 467 TYR A CD2 1 ATOM 3512 C CE1 . TYR A 1 431 ? 49.750 51.856 -1.762 1.00 30.86 ? 467 TYR A CE1 1 ATOM 3513 C CE2 . TYR A 1 431 ? 48.454 53.811 -1.261 1.00 32.71 ? 467 TYR A CE2 1 ATOM 3514 C CZ . TYR A 1 431 ? 49.059 52.977 -2.180 1.00 34.96 ? 467 TYR A CZ 1 ATOM 3515 O OH . TYR A 1 431 ? 48.966 53.255 -3.520 1.00 31.36 ? 467 TYR A OH 1 ATOM 3516 N N . TYR A 1 432 ? 49.320 49.911 4.257 1.00 25.20 ? 468 TYR A N 1 ATOM 3517 C CA . TYR A 1 432 ? 49.582 49.746 5.682 1.00 29.13 ? 468 TYR A CA 1 ATOM 3518 C C . TYR A 1 432 ? 51.054 49.564 5.974 1.00 30.37 ? 468 TYR A C 1 ATOM 3519 O O . TYR A 1 432 ? 51.793 48.993 5.161 1.00 27.89 ? 468 TYR A O 1 ATOM 3520 C CB . TYR A 1 432 ? 48.756 48.610 6.292 1.00 25.71 ? 468 TYR A CB 1 ATOM 3521 C CG . TYR A 1 432 ? 48.879 47.255 5.624 1.00 27.72 ? 468 TYR A CG 1 ATOM 3522 C CD1 . TYR A 1 432 ? 48.076 46.920 4.539 1.00 27.49 ? 468 TYR A CD1 1 ATOM 3523 C CD2 . TYR A 1 432 ? 49.763 46.295 6.106 1.00 27.25 ? 468 TYR A CD2 1 ATOM 3524 C CE1 . TYR A 1 432 ? 48.166 45.680 3.936 1.00 29.76 ? 468 TYR A CE1 1 ATOM 3525 C CE2 . TYR A 1 432 ? 49.857 45.047 5.517 1.00 25.93 ? 468 TYR A CE2 1 ATOM 3526 C CZ . TYR A 1 432 ? 49.055 44.749 4.425 1.00 33.22 ? 468 TYR A CZ 1 ATOM 3527 O OH . TYR A 1 432 ? 49.136 43.521 3.814 1.00 31.44 ? 468 TYR A OH 1 ATOM 3528 N N . GLN A 1 433 ? 51.468 50.090 7.126 1.00 25.59 ? 469 GLN A N 1 ATOM 3529 C CA . GLN A 1 433 ? 52.810 49.899 7.645 1.00 26.18 ? 469 GLN A CA 1 ATOM 3530 C C . GLN A 1 433 ? 52.762 48.812 8.691 1.00 29.05 ? 469 GLN A C 1 ATOM 3531 O O . GLN A 1 433 ? 52.007 48.924 9.661 1.00 26.45 ? 469 GLN A O 1 ATOM 3532 C CB . GLN A 1 433 ? 53.312 51.174 8.308 1.00 25.52 ? 469 GLN A CB 1 ATOM 3533 C CG . GLN A 1 433 ? 54.582 50.946 9.092 1.00 25.25 ? 469 GLN A CG 1 ATOM 3534 C CD . GLN A 1 433 ? 54.854 52.038 10.120 1.00 31.26 ? 469 GLN A CD 1 ATOM 3535 O OE1 . GLN A 1 433 ? 53.978 52.396 10.898 1.00 30.76 ? 469 GLN A OE1 1 ATOM 3536 N NE2 . GLN A 1 433 ? 56.074 52.571 10.122 1.00 30.18 ? 469 GLN A NE2 1 ATOM 3537 N N . LEU A 1 434 ? 53.546 47.755 8.508 1.00 25.02 ? 470 LEU A N 1 ATOM 3538 C CA . LEU A 1 434 ? 53.634 46.731 9.529 1.00 25.85 ? 470 LEU A CA 1 ATOM 3539 C C . LEU A 1 434 ? 54.811 47.062 10.430 1.00 30.03 ? 470 LEU A C 1 ATOM 3540 O O . LEU A 1 434 ? 55.855 47.497 9.955 1.00 29.66 ? 470 LEU A O 1 ATOM 3541 C CB . LEU A 1 434 ? 53.767 45.327 8.933 1.00 28.44 ? 470 LEU A CB 1 ATOM 3542 C CG . LEU A 1 434 ? 52.464 44.604 8.564 1.00 28.31 ? 470 LEU A CG 1 ATOM 3543 C CD1 . LEU A 1 434 ? 52.735 43.260 7.888 1.00 32.06 ? 470 LEU A CD1 1 ATOM 3544 C CD2 . LEU A 1 434 ? 51.568 44.379 9.762 1.00 26.86 ? 470 LEU A CD2 1 ATOM 3545 N N . ARG A 1 435 ? 54.612 46.907 11.734 1.00 26.93 ? 471 ARG A N 1 ATOM 3546 C CA . ARG A 1 435 ? 55.673 47.099 12.716 1.00 29.91 ? 471 ARG A CA 1 ATOM 3547 C C . ARG A 1 435 ? 55.841 45.819 13.510 1.00 29.44 ? 471 ARG A C 1 ATOM 3548 O O . ARG A 1 435 ? 54.965 45.445 14.299 1.00 31.05 ? 471 ARG A O 1 ATOM 3549 C CB . ARG A 1 435 ? 55.355 48.261 13.663 1.00 28.94 ? 471 ARG A CB 1 ATOM 3550 C CG . ARG A 1 435 ? 56.198 48.241 14.933 1.00 38.26 ? 471 ARG A CG 1 ATOM 3551 C CD . ARG A 1 435 ? 56.035 49.542 15.726 1.00 48.02 ? 471 ARG A CD 1 ATOM 3552 N NE . ARG A 1 435 ? 56.064 49.339 17.172 1.00 51.49 ? 471 ARG A NE 1 ATOM 3553 C CZ . ARG A 1 435 ? 55.047 49.631 17.984 1.00 64.38 ? 471 ARG A CZ 1 ATOM 3554 N NH1 . ARG A 1 435 ? 53.924 50.146 17.493 1.00 62.73 ? 471 ARG A NH1 1 ATOM 3555 N NH2 . ARG A 1 435 ? 55.152 49.418 19.293 1.00 71.82 ? 471 ARG A NH2 1 ATOM 3556 N N . CYS A 1 436 ? 56.955 45.133 13.281 1.00 30.11 ? 472 CYS A N 1 ATOM 3557 C CA . CYS A 1 436 ? 57.248 43.880 13.967 1.00 29.88 ? 472 CYS A CA 1 ATOM 3558 C C . CYS A 1 436 ? 58.123 44.246 15.153 1.00 30.31 ? 472 CYS A C 1 ATOM 3559 O O . CYS A 1 436 ? 59.094 44.980 14.997 1.00 29.65 ? 472 CYS A O 1 ATOM 3560 C CB . CYS A 1 436 ? 57.962 42.934 12.995 1.00 32.03 ? 472 CYS A CB 1 ATOM 3561 S SG . CYS A 1 436 ? 59.215 41.745 13.613 1.00 44.12 ? 472 CYS A SG 1 ATOM 3562 N N . SER A 1 437 ? 57.770 43.750 16.330 1.00 26.97 ? 473 SER A N 1 ATOM 3563 C CA . SER A 1 437 ? 58.459 44.109 17.574 1.00 30.14 ? 473 SER A CA 1 ATOM 3564 C C . SER A 1 437 ? 59.315 42.987 18.163 1.00 30.22 ? 473 SER A C 1 ATOM 3565 O O . SER A 1 437 ? 59.921 43.172 19.217 1.00 29.76 ? 473 SER A O 1 ATOM 3566 C CB . SER A 1 437 ? 57.436 44.516 18.645 1.00 31.85 ? 473 SER A CB 1 ATOM 3567 O OG . SER A 1 437 ? 56.862 45.775 18.364 1.00 39.21 ? 473 SER A OG 1 ATOM 3568 N N . GLY A 1 438 ? 59.331 41.817 17.527 1.00 26.53 ? 474 GLY A N 1 ATOM 3569 C CA . GLY A 1 438 ? 60.123 40.696 18.025 1.00 28.76 ? 474 GLY A CA 1 ATOM 3570 C C . GLY A 1 438 ? 59.657 39.362 17.471 1.00 31.17 ? 474 GLY A C 1 ATOM 3571 O O . GLY A 1 438 ? 58.610 39.289 16.835 1.00 29.52 ? 474 GLY A O 1 ATOM 3572 N N . PRO A 1 439 ? 60.381 38.278 17.776 1.00 28.23 ? 475 PRO A N 1 ATOM 3573 C CA . PRO A 1 439 ? 61.458 38.175 18.770 1.00 30.41 ? 475 PRO A CA 1 ATOM 3574 C C . PRO A 1 439 ? 62.784 38.732 18.291 1.00 33.07 ? 475 PRO A C 1 ATOM 3575 O O . PRO A 1 439 ? 63.670 38.903 19.116 1.00 34.37 ? 475 PRO A O 1 ATOM 3576 C CB . PRO A 1 439 ? 61.589 36.670 18.981 1.00 33.18 ? 475 PRO A CB 1 ATOM 3577 C CG . PRO A 1 439 ? 61.199 36.089 17.628 1.00 30.92 ? 475 PRO A CG 1 ATOM 3578 C CD . PRO A 1 439 ? 60.114 36.994 17.104 1.00 31.28 ? 475 PRO A CD 1 ATOM 3579 N N . GLY A 1 440 ? 62.924 39.010 16.996 1.00 32.82 ? 476 GLY A N 1 ATOM 3580 C CA . GLY A 1 440 ? 64.142 39.626 16.498 1.00 33.51 ? 476 GLY A CA 1 ATOM 3581 C C . GLY A 1 440 ? 64.103 41.142 16.641 1.00 35.65 ? 476 GLY A C 1 ATOM 3582 O O . GLY A 1 440 ? 63.207 41.692 17.292 1.00 29.71 ? 476 GLY A O 1 ATOM 3583 N N . LEU A 1 441 ? 65.078 41.825 16.046 1.00 30.17 ? 477 LEU A N 1 ATOM 3584 C CA . LEU A 1 441 ? 65.091 43.286 16.088 1.00 33.73 ? 477 LEU A CA 1 ATOM 3585 C C . LEU A 1 441 ? 63.885 43.848 15.342 1.00 33.88 ? 477 LEU A C 1 ATOM 3586 O O . LEU A 1 441 ? 63.476 43.303 14.317 1.00 31.26 ? 477 LEU A O 1 ATOM 3587 C CB . LEU A 1 441 ? 66.389 43.846 15.496 1.00 31.92 ? 477 LEU A CB 1 ATOM 3588 C CG . LEU A 1 441 ? 67.688 43.487 16.235 1.00 32.96 ? 477 LEU A CG 1 ATOM 3589 C CD1 . LEU A 1 441 ? 68.843 44.293 15.695 1.00 33.56 ? 477 LEU A CD1 1 ATOM 3590 C CD2 . LEU A 1 441 ? 67.552 43.731 17.728 1.00 32.00 ? 477 LEU A CD2 1 ATOM 3591 N N . PRO A 1 442 ? 63.298 44.931 15.864 1.00 34.86 ? 478 PRO A N 1 ATOM 3592 C CA . PRO A 1 442 ? 62.134 45.545 15.214 1.00 33.47 ? 478 PRO A CA 1 ATOM 3593 C C . PRO A 1 442 ? 62.362 45.800 13.736 1.00 34.44 ? 478 PRO A C 1 ATOM 3594 O O . PRO A 1 442 ? 63.460 46.214 13.335 1.00 32.53 ? 478 PRO A O 1 ATOM 3595 C CB . PRO A 1 442 ? 61.983 46.874 15.957 1.00 31.13 ? 478 PRO A CB 1 ATOM 3596 C CG . PRO A 1 442 ? 62.455 46.548 17.338 1.00 35.12 ? 478 PRO A CG 1 ATOM 3597 C CD . PRO A 1 442 ? 63.623 45.589 17.140 1.00 31.77 ? 478 PRO A CD 1 ATOM 3598 N N . LEU A 1 443 ? 61.314 45.574 12.946 1.00 28.06 ? 479 LEU A N 1 ATOM 3599 C CA . LEU A 1 443 ? 61.383 45.684 11.496 1.00 29.89 ? 479 LEU A CA 1 ATOM 3600 C C . LEU A 1 443 ? 60.120 46.383 11.016 1.00 27.81 ? 479 LEU A C 1 ATOM 3601 O O . LEU A 1 443 ? 59.021 45.941 11.322 1.00 28.04 ? 479 LEU A O 1 ATOM 3602 C CB . LEU A 1 443 ? 61.494 44.297 10.860 1.00 29.55 ? 479 LEU A CB 1 ATOM 3603 C CG . LEU A 1 443 ? 61.405 44.241 9.336 1.00 28.79 ? 479 LEU A CG 1 ATOM 3604 C CD1 . LEU A 1 443 ? 62.459 45.132 8.709 1.00 29.00 ? 479 LEU A CD1 1 ATOM 3605 C CD2 . LEU A 1 443 ? 61.540 42.805 8.829 1.00 30.56 ? 479 LEU A CD2 1 ATOM 3606 N N . TYR A 1 444 ? 60.286 47.489 10.299 1.00 23.93 ? 480 TYR A N 1 ATOM 3607 C CA . TYR A 1 444 ? 59.171 48.302 9.834 1.00 30.34 ? 480 TYR A CA 1 ATOM 3608 C C . TYR A 1 444 ? 59.070 48.214 8.313 1.00 28.28 ? 480 TYR A C 1 ATOM 3609 O O . TYR A 1 444 ? 60.038 48.504 7.625 1.00 29.78 ? 480 TYR A O 1 ATOM 3610 C CB . TYR A 1 444 ? 59.373 49.766 10.264 1.00 30.19 ? 480 TYR A CB 1 ATOM 3611 C CG . TYR A 1 444 ? 59.410 49.957 11.771 1.00 31.36 ? 480 TYR A CG 1 ATOM 3612 C CD1 . TYR A 1 444 ? 60.557 49.663 12.505 1.00 32.50 ? 480 TYR A CD1 1 ATOM 3613 C CD2 . TYR A 1 444 ? 58.299 50.429 12.459 1.00 30.82 ? 480 TYR A CD2 1 ATOM 3614 C CE1 . TYR A 1 444 ? 60.597 49.841 13.893 1.00 32.49 ? 480 TYR A CE1 1 ATOM 3615 C CE2 . TYR A 1 444 ? 58.330 50.620 13.843 1.00 35.07 ? 480 TYR A CE2 1 ATOM 3616 C CZ . TYR A 1 444 ? 59.476 50.312 14.553 1.00 37.68 ? 480 TYR A CZ 1 ATOM 3617 O OH . TYR A 1 444 ? 59.509 50.482 15.924 1.00 39.71 ? 480 TYR A OH 1 ATOM 3618 N N . THR A 1 445 ? 57.907 47.811 7.796 1.00 29.77 ? 481 THR A N 1 ATOM 3619 C CA . THR A 1 445 ? 57.713 47.636 6.348 1.00 26.43 ? 481 THR A CA 1 ATOM 3620 C C . THR A 1 445 ? 56.412 48.292 5.871 1.00 31.00 ? 481 THR A C 1 ATOM 3621 O O . THR A 1 445 ? 55.479 48.473 6.660 1.00 26.64 ? 481 THR A O 1 ATOM 3622 C CB . THR A 1 445 ? 57.684 46.136 5.954 1.00 27.89 ? 481 THR A CB 1 ATOM 3623 O OG1 . THR A 1 445 ? 56.759 45.434 6.804 1.00 32.56 ? 481 THR A OG1 1 ATOM 3624 C CG2 . THR A 1 445 ? 59.050 45.516 6.139 1.00 25.95 ? 481 THR A CG2 1 ATOM 3625 N N . LEU A 1 446 ? 56.358 48.657 4.587 1.00 26.92 ? 482 LEU A N 1 ATOM 3626 C CA . LEU A 1 446 ? 55.154 49.228 3.974 1.00 24.70 ? 482 LEU A CA 1 ATOM 3627 C C . LEU A 1 446 ? 54.552 48.261 2.951 1.00 32.51 ? 482 LEU A C 1 ATOM 3628 O O . LEU A 1 446 ? 55.288 47.586 2.230 1.00 28.56 ? 482 LEU A O 1 ATOM 3629 C CB . LEU A 1 446 ? 55.480 50.545 3.275 1.00 26.71 ? 482 LEU A CB 1 ATOM 3630 C CG . LEU A 1 446 ? 54.304 51.502 3.071 1.00 30.63 ? 482 LEU A CG 1 ATOM 3631 C CD1 . LEU A 1 446 ? 53.831 52.047 4.416 1.00 26.13 ? 482 LEU A CD1 1 ATOM 3632 C CD2 . LEU A 1 446 ? 54.697 52.653 2.160 1.00 30.33 ? 482 LEU A CD2 1 ATOM 3633 N N . HIS A 1 447 ? 53.221 48.223 2.873 1.00 28.29 ? 483 HIS A N 1 ATOM 3634 C CA . HIS A 1 447 ? 52.507 47.274 2.027 1.00 29.17 ? 483 HIS A CA 1 ATOM 3635 C C . HIS A 1 447 ? 51.296 47.962 1.404 1.00 32.54 ? 483 HIS A C 1 ATOM 3636 O O . HIS A 1 447 ? 50.758 48.911 1.984 1.00 29.53 ? 483 HIS A O 1 ATOM 3637 C CB . HIS A 1 447 ? 52.020 46.094 2.863 1.00 32.28 ? 483 HIS A CB 1 ATOM 3638 C CG . HIS A 1 447 ? 53.091 45.456 3.689 1.00 31.59 ? 483 HIS A CG 1 ATOM 3639 N ND1 . HIS A 1 447 ? 53.645 44.233 3.373 1.00 29.73 ? 483 HIS A ND1 1 ATOM 3640 C CD2 . HIS A 1 447 ? 53.717 45.875 4.815 1.00 28.81 ? 483 HIS A CD2 1 ATOM 3641 C CE1 . HIS A 1 447 ? 54.569 43.927 4.267 1.00 33.71 ? 483 HIS A CE1 1 ATOM 3642 N NE2 . HIS A 1 447 ? 54.625 44.903 5.159 1.00 33.15 ? 483 HIS A NE2 1 ATOM 3643 N N . SER A 1 448 ? 50.869 47.498 0.228 1.00 32.69 ? 484 SER A N 1 ATOM 3644 C CA . SER A 1 448 ? 49.617 47.970 -0.350 1.00 32.66 ? 484 SER A CA 1 ATOM 3645 C C . SER A 1 448 ? 48.541 46.914 -0.160 1.00 33.62 ? 484 SER A C 1 ATOM 3646 O O . SER A 1 448 ? 48.799 45.715 -0.267 1.00 34.81 ? 484 SER A O 1 ATOM 3647 C CB . SER A 1 448 ? 49.767 48.299 -1.827 1.00 35.10 ? 484 SER A CB 1 ATOM 3648 O OG . SER A 1 448 ? 50.125 47.137 -2.525 1.00 39.39 ? 484 SER A OG 1 ATOM 3649 N N . SER A 1 449 ? 47.332 47.377 0.121 1.00 32.32 ? 485 SER A N 1 ATOM 3650 C CA . SER A 1 449 ? 46.223 46.500 0.460 1.00 33.49 ? 485 SER A CA 1 ATOM 3651 C C . SER A 1 449 ? 45.680 45.750 -0.753 1.00 36.51 ? 485 SER A C 1 ATOM 3652 O O . SER A 1 449 ? 45.204 44.624 -0.622 1.00 32.97 ? 485 SER A O 1 ATOM 3653 C CB . SER A 1 449 ? 45.100 47.314 1.108 1.00 32.96 ? 485 SER A CB 1 ATOM 3654 O OG . SER A 1 449 ? 45.532 47.840 2.361 1.00 35.61 ? 485 SER A OG 1 ATOM 3655 N N . VAL A 1 450 ? 45.753 46.368 -1.929 1.00 36.55 ? 486 VAL A N 1 ATOM 3656 C CA . VAL A 1 450 ? 45.092 45.787 -3.106 1.00 43.70 ? 486 VAL A CA 1 ATOM 3657 C C . VAL A 1 450 ? 45.387 44.294 -3.284 1.00 41.00 ? 486 VAL A C 1 ATOM 3658 O O . VAL A 1 450 ? 44.465 43.482 -3.391 1.00 47.52 ? 486 VAL A O 1 ATOM 3659 C CB . VAL A 1 450 ? 45.341 46.591 -4.405 1.00 40.69 ? 486 VAL A CB 1 ATOM 3660 C CG1 . VAL A 1 450 ? 46.822 46.797 -4.656 1.00 38.84 ? 486 VAL A CG1 1 ATOM 3661 C CG2 . VAL A 1 450 ? 44.678 45.897 -5.575 1.00 50.12 ? 486 VAL A CG2 1 ATOM 3662 N N . ASN A 1 451 ? 46.661 43.925 -3.287 1.00 38.48 ? 487 ASN A N 1 ATOM 3663 C CA . ASN A 1 451 ? 47.031 42.509 -3.315 1.00 43.71 ? 487 ASN A CA 1 ATOM 3664 C C . ASN A 1 451 ? 47.986 42.106 -2.189 1.00 42.13 ? 487 ASN A C 1 ATOM 3665 O O . ASN A 1 451 ? 48.647 41.068 -2.265 1.00 43.96 ? 487 ASN A O 1 ATOM 3666 C CB . ASN A 1 451 ? 47.636 42.138 -4.673 1.00 48.50 ? 487 ASN A CB 1 ATOM 3667 C CG . ASN A 1 451 ? 46.574 41.867 -5.727 1.00 58.52 ? 487 ASN A CG 1 ATOM 3668 O OD1 . ASN A 1 451 ? 46.401 42.651 -6.664 1.00 57.29 ? 487 ASN A OD1 1 ATOM 3669 N ND2 . ASN A 1 451 ? 45.856 40.751 -5.577 1.00 56.87 ? 487 ASN A ND2 1 ATOM 3670 N N . ASP A 1 452 ? 48.061 42.935 -1.150 1.00 40.76 ? 488 ASP A N 1 ATOM 3671 C CA . ASP A 1 452 ? 48.920 42.656 -0.003 1.00 37.75 ? 488 ASP A CA 1 ATOM 3672 C C . ASP A 1 452 ? 50.366 42.442 -0.416 1.00 38.32 ? 488 ASP A C 1 ATOM 3673 O O . ASP A 1 452 ? 51.033 41.534 0.072 1.00 39.82 ? 488 ASP A O 1 ATOM 3674 C CB . ASP A 1 452 ? 48.398 41.438 0.753 1.00 38.63 ? 488 ASP A CB 1 ATOM 3675 C CG . ASP A 1 452 ? 47.038 41.691 1.371 1.00 44.06 ? 488 ASP A CG 1 ATOM 3676 O OD1 . ASP A 1 452 ? 46.934 42.652 2.176 1.00 37.24 ? 488 ASP A OD1 1 ATOM 3677 O OD2 . ASP A 1 452 ? 46.078 40.957 1.028 1.00 39.63 ? 488 ASP A OD2 1 ATOM 3678 N N . LYS A 1 453 ? 50.844 43.290 -1.315 1.00 38.20 ? 489 LYS A N 1 ATOM 3679 C CA . LYS A 1 453 ? 52.207 43.188 -1.818 1.00 41.22 ? 489 LYS A CA 1 ATOM 3680 C C . LYS A 1 453 ? 53.107 44.060 -0.964 1.00 40.49 ? 489 LYS A C 1 ATOM 3681 O O . LYS A 1 453 ? 52.735 45.188 -0.620 1.00 38.87 ? 489 LYS A O 1 ATOM 3682 C CB . LYS A 1 453 ? 52.270 43.650 -3.280 1.00 46.12 ? 489 LYS A CB 1 ATOM 3683 C CG . LYS A 1 453 ? 53.663 43.567 -3.908 1.00 48.26 ? 489 LYS A CG 1 ATOM 3684 C CD . LYS A 1 453 ? 53.672 44.081 -5.354 1.00 55.12 ? 489 LYS A CD 1 ATOM 3685 C CE . LYS A 1 453 ? 53.915 45.595 -5.430 1.00 59.14 ? 489 LYS A CE 1 ATOM 3686 N NZ . LYS A 1 453 ? 55.372 45.963 -5.365 1.00 52.51 ? 489 LYS A NZ 1 ATOM 3687 N N . GLY A 1 454 ? 54.273 43.528 -0.604 1.00 38.36 ? 490 GLY A N 1 ATOM 3688 C CA . GLY A 1 454 ? 55.270 44.286 0.125 1.00 35.05 ? 490 GLY A CA 1 ATOM 3689 C C . GLY A 1 454 ? 55.839 45.341 -0.795 1.00 38.61 ? 490 GLY A C 1 ATOM 3690 O O . GLY A 1 454 ? 56.241 45.043 -1.925 1.00 42.36 ? 490 GLY A O 1 ATOM 3691 N N . LEU A 1 455 ? 55.847 46.590 -0.344 1.00 29.96 ? 491 LEU A N 1 ATOM 3692 C CA . LEU A 1 455 ? 56.351 47.667 -1.185 1.00 29.48 ? 491 LEU A CA 1 ATOM 3693 C C . LEU A 1 455 ? 57.834 47.876 -0.939 1.00 33.75 ? 491 LEU A C 1 ATOM 3694 O O . LEU A 1 455 ? 58.637 47.747 -1.867 1.00 30.50 ? 491 LEU A O 1 ATOM 3695 C CB . LEU A 1 455 ? 55.567 48.957 -0.958 1.00 31.29 ? 491 LEU A CB 1 ATOM 3696 C CG . LEU A 1 455 ? 54.139 48.901 -1.505 1.00 32.87 ? 491 LEU A CG 1 ATOM 3697 C CD1 . LEU A 1 455 ? 53.309 50.060 -0.969 1.00 28.68 ? 491 LEU A CD1 1 ATOM 3698 C CD2 . LEU A 1 455 ? 54.142 48.885 -3.021 1.00 30.37 ? 491 LEU A CD2 1 ATOM 3699 N N . ARG A 1 456 ? 58.194 48.168 0.314 1.00 30.11 ? 492 ARG A N 1 ATOM 3700 C CA . ARG A 1 456 ? 59.589 48.419 0.675 1.00 28.57 ? 492 ARG A CA 1 ATOM 3701 C C . ARG A 1 456 ? 59.820 48.323 2.181 1.00 30.75 ? 492 ARG A C 1 ATOM 3702 O O . ARG A 1 456 ? 58.884 48.425 2.981 1.00 27.72 ? 492 ARG A O 1 ATOM 3703 C CB . ARG A 1 456 ? 60.037 49.798 0.175 1.00 31.54 ? 492 ARG A CB 1 ATOM 3704 C CG . ARG A 1 456 ? 59.367 50.977 0.883 1.00 26.59 ? 492 ARG A CG 1 ATOM 3705 C CD . ARG A 1 456 ? 59.497 52.246 0.068 1.00 27.66 ? 492 ARG A CD 1 ATOM 3706 N NE . ARG A 1 456 ? 58.758 52.095 -1.185 1.00 28.44 ? 492 ARG A NE 1 ATOM 3707 C CZ . ARG A 1 456 ? 57.496 52.476 -1.371 1.00 32.43 ? 492 ARG A CZ 1 ATOM 3708 N NH1 . ARG A 1 456 ? 56.822 53.073 -0.391 1.00 26.33 ? 492 ARG A NH1 1 ATOM 3709 N NH2 . ARG A 1 456 ? 56.903 52.266 -2.544 1.00 29.24 ? 492 ARG A NH2 1 ATOM 3710 N N . VAL A 1 457 ? 61.074 48.115 2.557 1.00 29.03 ? 493 VAL A N 1 ATOM 3711 C CA . VAL A 1 457 ? 61.466 48.089 3.954 1.00 30.70 ? 493 VAL A CA 1 ATOM 3712 C C . VAL A 1 457 ? 61.725 49.524 4.398 1.00 33.35 ? 493 VAL A C 1 ATOM 3713 O O . VAL A 1 457 ? 62.425 50.265 3.712 1.00 29.29 ? 493 VAL A O 1 ATOM 3714 C CB . VAL A 1 457 ? 62.726 47.247 4.161 1.00 35.68 ? 493 VAL A CB 1 ATOM 3715 C CG1 . VAL A 1 457 ? 63.204 47.359 5.601 1.00 31.69 ? 493 VAL A CG1 1 ATOM 3716 C CG2 . VAL A 1 457 ? 62.457 45.780 3.797 1.00 34.59 ? 493 VAL A CG2 1 ATOM 3717 N N . LEU A 1 458 ? 61.149 49.920 5.534 1.00 28.50 ? 494 LEU A N 1 ATOM 3718 C CA . LEU A 1 458 ? 61.293 51.292 6.020 1.00 28.75 ? 494 LEU A CA 1 ATOM 3719 C C . LEU A 1 458 ? 62.435 51.447 7.045 1.00 29.87 ? 494 LEU A C 1 ATOM 3720 O O . LEU A 1 458 ? 63.184 52.423 7.017 1.00 29.62 ? 494 LEU A O 1 ATOM 3721 C CB . LEU A 1 458 ? 59.968 51.767 6.640 1.00 31.60 ? 494 LEU A CB 1 ATOM 3722 C CG . LEU A 1 458 ? 58.708 51.716 5.775 1.00 28.52 ? 494 LEU A CG 1 ATOM 3723 C CD1 . LEU A 1 458 ? 57.459 51.941 6.619 1.00 28.47 ? 494 LEU A CD1 1 ATOM 3724 C CD2 . LEU A 1 458 ? 58.781 52.749 4.662 1.00 28.45 ? 494 LEU A CD2 1 ATOM 3725 N N . GLU A 1 459 ? 62.537 50.500 7.972 1.00 28.37 ? 495 GLU A N 1 ATOM 3726 C CA . GLU A 1 459 ? 63.627 50.482 8.948 1.00 28.60 ? 495 GLU A CA 1 ATOM 3727 C C . GLU A 1 459 ? 63.826 49.057 9.406 1.00 29.74 ? 495 GLU A C 1 ATOM 3728 O O . GLU A 1 459 ? 62.868 48.420 9.852 1.00 31.27 ? 495 GLU A O 1 ATOM 3729 C CB . GLU A 1 459 ? 63.318 51.386 10.156 1.00 30.15 ? 495 GLU A CB 1 ATOM 3730 C CG . GLU A 1 459 ? 64.370 51.302 11.298 1.00 32.86 ? 495 GLU A CG 1 ATOM 3731 C CD . GLU A 1 459 ? 65.785 51.708 10.843 1.00 36.48 ? 495 GLU A CD 1 ATOM 3732 O OE1 . GLU A 1 459 ? 65.969 52.857 10.367 1.00 42.95 ? 495 GLU A OE1 1 ATOM 3733 O OE2 . GLU A 1 459 ? 66.712 50.868 10.933 1.00 34.14 ? 495 GLU A OE2 1 ATOM 3734 N N . ASP A 1 460 ? 65.054 48.544 9.292 1.00 30.49 ? 496 ASP A N 1 ATOM 3735 C CA . ASP A 1 460 ? 65.340 47.165 9.688 1.00 28.75 ? 496 ASP A CA 1 ATOM 3736 C C . ASP A 1 460 ? 66.351 47.057 10.842 1.00 29.62 ? 496 ASP A C 1 ATOM 3737 O O . ASP A 1 460 ? 66.792 45.966 11.181 1.00 27.51 ? 496 ASP A O 1 ATOM 3738 C CB . ASP A 1 460 ? 65.834 46.341 8.492 1.00 30.51 ? 496 ASP A CB 1 ATOM 3739 C CG . ASP A 1 460 ? 67.122 46.893 7.899 1.00 41.19 ? 496 ASP A CG 1 ATOM 3740 O OD1 . ASP A 1 460 ? 67.736 47.793 8.529 1.00 36.04 ? 496 ASP A OD1 1 ATOM 3741 O OD2 . ASP A 1 460 ? 67.522 46.432 6.799 1.00 46.10 ? 496 ASP A OD2 1 ATOM 3742 N N . ASN A 1 461 ? 66.725 48.187 11.432 1.00 29.39 ? 497 ASN A N 1 ATOM 3743 C CA . ASN A 1 461 ? 67.648 48.182 12.568 1.00 30.26 ? 497 ASN A CA 1 ATOM 3744 C C . ASN A 1 461 ? 68.993 47.477 12.316 1.00 31.57 ? 497 ASN A C 1 ATOM 3745 O O . ASN A 1 461 ? 69.585 46.899 13.232 1.00 29.20 ? 497 ASN A O 1 ATOM 3746 C CB . ASN A 1 461 ? 66.953 47.622 13.828 1.00 27.58 ? 497 ASN A CB 1 ATOM 3747 C CG . ASN A 1 461 ? 66.187 48.695 14.593 1.00 31.96 ? 497 ASN A CG 1 ATOM 3748 O OD1 . ASN A 1 461 ? 66.786 49.549 15.246 1.00 29.10 ? 497 ASN A OD1 1 ATOM 3749 N ND2 . ASN A 1 461 ? 64.857 48.662 14.507 1.00 33.43 ? 497 ASN A ND2 1 ATOM 3750 N N . SER A 1 462 ? 69.475 47.541 11.073 1.00 35.16 ? 498 SER A N 1 ATOM 3751 C CA . SER A 1 462 ? 70.760 46.952 10.716 1.00 32.90 ? 498 SER A CA 1 ATOM 3752 C C . SER A 1 462 ? 71.871 47.552 11.567 1.00 35.06 ? 498 SER A C 1 ATOM 3753 O O . SER A 1 462 ? 72.769 46.835 12.009 1.00 32.86 ? 498 SER A O 1 ATOM 3754 C CB . SER A 1 462 ? 71.067 47.154 9.223 1.00 33.07 ? 498 SER A CB 1 ATOM 3755 O OG . SER A 1 462 ? 71.051 48.534 8.884 1.00 41.67 ? 498 SER A OG 1 ATOM 3756 N N . ALA A 1 463 ? 71.800 48.861 11.803 1.00 34.49 ? 499 ALA A N 1 ATOM 3757 C CA . ALA A 1 463 ? 72.776 49.540 12.652 1.00 36.94 ? 499 ALA A CA 1 ATOM 3758 C C . ALA A 1 463 ? 72.869 48.899 14.044 1.00 39.47 ? 499 ALA A C 1 ATOM 3759 O O . ALA A 1 463 ? 73.954 48.505 14.488 1.00 38.46 ? 499 ALA A O 1 ATOM 3760 C CB . ALA A 1 463 ? 72.447 51.022 12.767 1.00 41.09 ? 499 ALA A CB 1 ATOM 3761 N N . LEU A 1 464 ? 71.740 48.800 14.738 1.00 35.50 ? 500 LEU A N 1 ATOM 3762 C CA . LEU A 1 464 ? 71.720 48.095 16.007 1.00 34.87 ? 500 LEU A CA 1 ATOM 3763 C C . LEU A 1 464 ? 72.222 46.667 15.855 1.00 32.80 ? 500 LEU A C 1 ATOM 3764 O O . LEU A 1 464 ? 72.986 46.182 16.684 1.00 35.18 ? 500 LEU A O 1 ATOM 3765 C CB . LEU A 1 464 ? 70.318 48.079 16.611 1.00 35.80 ? 500 LEU A CB 1 ATOM 3766 C CG . LEU A 1 464 ? 70.230 47.335 17.948 1.00 34.31 ? 500 LEU A CG 1 ATOM 3767 C CD1 . LEU A 1 464 ? 71.209 47.926 18.981 1.00 37.23 ? 500 LEU A CD1 1 ATOM 3768 C CD2 . LEU A 1 464 ? 68.814 47.376 18.486 1.00 34.77 ? 500 LEU A CD2 1 ATOM 3769 N N . ASP A 1 465 ? 71.794 45.987 14.800 1.00 33.65 ? 501 ASP A N 1 ATOM 3770 C CA . ASP A 1 465 ? 72.188 44.594 14.621 1.00 34.36 ? 501 ASP A CA 1 ATOM 3771 C C . ASP A 1 465 ? 73.706 44.430 14.627 1.00 38.64 ? 501 ASP A C 1 ATOM 3772 O O . ASP A 1 465 ? 74.239 43.545 15.303 1.00 36.71 ? 501 ASP A O 1 ATOM 3773 C CB . ASP A 1 465 ? 71.614 44.007 13.339 1.00 37.86 ? 501 ASP A CB 1 ATOM 3774 C CG . ASP A 1 465 ? 71.821 42.511 13.252 1.00 46.95 ? 501 ASP A CG 1 ATOM 3775 O OD1 . ASP A 1 465 ? 71.399 41.793 14.186 1.00 50.74 ? 501 ASP A OD1 1 ATOM 3776 O OD2 . ASP A 1 465 ? 72.407 42.047 12.254 1.00 52.50 ? 501 ASP A OD2 1 ATOM 3777 N N . LYS A 1 466 ? 74.393 45.295 13.883 1.00 37.87 ? 502 LYS A N 1 ATOM 3778 C CA . LYS A 1 466 ? 75.848 45.230 13.764 1.00 39.92 ? 502 LYS A CA 1 ATOM 3779 C C . LYS A 1 466 ? 76.539 45.473 15.117 1.00 38.59 ? 502 LYS A C 1 ATOM 3780 O O . LYS A 1 466 ? 77.533 44.821 15.441 1.00 39.03 ? 502 LYS A O 1 ATOM 3781 C CB . LYS A 1 466 ? 76.349 46.218 12.698 1.00 36.81 ? 502 LYS A CB 1 ATOM 3782 N N . MET A 1 467 ? 75.999 46.393 15.914 1.00 37.54 ? 503 MET A N 1 ATOM 3783 C CA . MET A 1 467 ? 76.547 46.648 17.244 1.00 37.69 ? 503 MET A CA 1 ATOM 3784 C C . MET A 1 467 ? 76.354 45.475 18.195 1.00 40.10 ? 503 MET A C 1 ATOM 3785 O O . MET A 1 467 ? 77.257 45.133 18.950 1.00 39.77 ? 503 MET A O 1 ATOM 3786 C CB . MET A 1 467 ? 75.928 47.895 17.861 1.00 39.78 ? 503 MET A CB 1 ATOM 3787 C CG . MET A 1 467 ? 76.378 49.191 17.231 1.00 39.00 ? 503 MET A CG 1 ATOM 3788 S SD . MET A 1 467 ? 75.819 50.578 18.236 1.00 52.71 ? 503 MET A SD 1 ATOM 3789 C CE . MET A 1 467 ? 74.055 50.592 17.888 1.00 47.70 ? 503 MET A CE 1 ATOM 3790 N N . LEU A 1 468 ? 75.177 44.861 18.174 1.00 38.87 ? 504 LEU A N 1 ATOM 3791 C CA . LEU A 1 468 ? 74.891 43.794 19.128 1.00 38.17 ? 504 LEU A CA 1 ATOM 3792 C C . LEU A 1 468 ? 75.668 42.516 18.849 1.00 38.09 ? 504 LEU A C 1 ATOM 3793 O O . LEU A 1 468 ? 75.825 41.676 19.733 1.00 40.73 ? 504 LEU A O 1 ATOM 3794 C CB . LEU A 1 468 ? 73.387 43.515 19.233 1.00 36.37 ? 504 LEU A CB 1 ATOM 3795 C CG . LEU A 1 468 ? 72.590 44.663 19.861 1.00 35.76 ? 504 LEU A CG 1 ATOM 3796 C CD1 . LEU A 1 468 ? 71.119 44.312 19.942 1.00 35.03 ? 504 LEU A CD1 1 ATOM 3797 C CD2 . LEU A 1 468 ? 73.126 45.002 21.237 1.00 37.00 ? 504 LEU A CD2 1 ATOM 3798 N N . GLN A 1 469 ? 76.166 42.367 17.628 1.00 39.99 ? 505 GLN A N 1 ATOM 3799 C CA . GLN A 1 469 ? 76.990 41.205 17.315 1.00 42.55 ? 505 GLN A CA 1 ATOM 3800 C C . GLN A 1 469 ? 78.274 41.189 18.145 1.00 39.53 ? 505 GLN A C 1 ATOM 3801 O O . GLN A 1 469 ? 78.853 40.133 18.387 1.00 40.66 ? 505 GLN A O 1 ATOM 3802 C CB . GLN A 1 469 ? 77.279 41.130 15.808 1.00 46.06 ? 505 GLN A CB 1 ATOM 3803 C CG . GLN A 1 469 ? 75.994 41.118 14.987 1.00 46.45 ? 505 GLN A CG 1 ATOM 3804 C CD . GLN A 1 469 ? 76.189 40.667 13.568 1.00 58.64 ? 505 GLN A CD 1 ATOM 3805 O OE1 . GLN A 1 469 ? 77.142 39.950 13.258 1.00 72.32 ? 505 GLN A OE1 1 ATOM 3806 N NE2 . GLN A 1 469 ? 75.280 41.079 12.685 1.00 56.75 ? 505 GLN A NE2 1 ATOM 3807 N N . ASN A 1 470 ? 78.698 42.360 18.610 1.00 41.25 ? 506 ASN A N 1 ATOM 3808 C CA . ASN A 1 470 ? 79.906 42.464 19.422 1.00 40.73 ? 506 ASN A CA 1 ATOM 3809 C C . ASN A 1 470 ? 79.658 42.250 20.910 1.00 42.45 ? 506 ASN A C 1 ATOM 3810 O O . ASN A 1 470 ? 80.590 42.326 21.709 1.00 43.49 ? 506 ASN A O 1 ATOM 3811 C CB . ASN A 1 470 ? 80.560 43.831 19.243 1.00 42.10 ? 506 ASN A CB 1 ATOM 3812 C CG . ASN A 1 470 ? 80.881 44.138 17.805 1.00 50.79 ? 506 ASN A CG 1 ATOM 3813 O OD1 . ASN A 1 470 ? 80.823 45.296 17.375 1.00 53.49 ? 506 ASN A OD1 1 ATOM 3814 N ND2 . ASN A 1 470 ? 81.213 43.100 17.040 1.00 47.86 ? 506 ASN A ND2 1 ATOM 3815 N N . VAL A 1 471 ? 78.408 41.998 21.282 1.00 39.60 ? 507 VAL A N 1 ATOM 3816 C CA . VAL A 1 471 ? 78.039 41.905 22.698 1.00 39.67 ? 507 VAL A CA 1 ATOM 3817 C C . VAL A 1 471 ? 77.563 40.500 23.034 1.00 36.36 ? 507 VAL A C 1 ATOM 3818 O O . VAL A 1 471 ? 76.913 39.843 22.222 1.00 37.74 ? 507 VAL A O 1 ATOM 3819 C CB . VAL A 1 471 ? 76.927 42.931 23.067 1.00 37.21 ? 507 VAL A CB 1 ATOM 3820 C CG1 . VAL A 1 471 ? 76.585 42.862 24.547 1.00 38.58 ? 507 VAL A CG1 1 ATOM 3821 C CG2 . VAL A 1 471 ? 77.340 44.333 22.691 1.00 35.25 ? 507 VAL A CG2 1 ATOM 3822 N N . GLN A 1 472 ? 77.901 40.026 24.225 1.00 37.44 ? 508 GLN A N 1 ATOM 3823 C CA . GLN A 1 472 ? 77.342 38.766 24.701 1.00 41.57 ? 508 GLN A CA 1 ATOM 3824 C C . GLN A 1 472 ? 75.904 38.962 25.186 1.00 36.59 ? 508 GLN A C 1 ATOM 3825 O O . GLN A 1 472 ? 75.664 39.166 26.375 1.00 40.24 ? 508 GLN A O 1 ATOM 3826 C CB . GLN A 1 472 ? 78.209 38.167 25.806 1.00 43.26 ? 508 GLN A CB 1 ATOM 3827 C CG . GLN A 1 472 ? 79.468 37.493 25.296 1.00 51.35 ? 508 GLN A CG 1 ATOM 3828 C CD . GLN A 1 472 ? 80.420 37.137 26.412 1.00 55.32 ? 508 GLN A CD 1 ATOM 3829 O OE1 . GLN A 1 472 ? 80.972 38.018 27.074 1.00 59.51 ? 508 GLN A OE1 1 ATOM 3830 N NE2 . GLN A 1 472 ? 80.618 35.841 26.635 1.00 58.14 ? 508 GLN A NE2 1 ATOM 3831 N N . MET A 1 473 ? 74.950 38.883 24.263 1.00 34.21 ? 509 MET A N 1 ATOM 3832 C CA . MET A 1 473 ? 73.555 39.145 24.593 1.00 34.85 ? 509 MET A CA 1 ATOM 3833 C C . MET A 1 473 ? 72.884 37.917 25.165 1.00 36.29 ? 509 MET A C 1 ATOM 3834 O O . MET A 1 473 ? 73.279 36.785 24.878 1.00 37.49 ? 509 MET A O 1 ATOM 3835 C CB . MET A 1 473 ? 72.773 39.624 23.364 1.00 36.28 ? 509 MET A CB 1 ATOM 3836 C CG . MET A 1 473 ? 73.223 40.968 22.830 1.00 38.28 ? 509 MET A CG 1 ATOM 3837 S SD . MET A 1 473 ? 73.091 42.266 24.074 1.00 42.48 ? 509 MET A SD 1 ATOM 3838 C CE . MET A 1 473 ? 71.318 42.475 24.153 1.00 38.95 ? 509 MET A CE 1 ATOM 3839 N N . PRO A 1 474 ? 71.848 38.137 25.975 1.00 34.31 ? 510 PRO A N 1 ATOM 3840 C CA . PRO A 1 474 ? 71.072 37.018 26.504 1.00 33.73 ? 510 PRO A CA 1 ATOM 3841 C C . PRO A 1 474 ? 70.095 36.492 25.448 1.00 33.77 ? 510 PRO A C 1 ATOM 3842 O O . PRO A 1 474 ? 69.722 37.225 24.535 1.00 32.64 ? 510 PRO A O 1 ATOM 3843 C CB . PRO A 1 474 ? 70.321 37.649 27.688 1.00 33.85 ? 510 PRO A CB 1 ATOM 3844 C CG . PRO A 1 474 ? 70.165 39.077 27.325 1.00 33.10 ? 510 PRO A CG 1 ATOM 3845 C CD . PRO A 1 474 ? 71.341 39.444 26.438 1.00 36.28 ? 510 PRO A CD 1 ATOM 3846 N N . SER A 1 475 ? 69.711 35.226 25.554 1.00 33.39 ? 511 SER A N 1 ATOM 3847 C CA . SER A 1 475 ? 68.648 34.691 24.713 1.00 34.61 ? 511 SER A CA 1 ATOM 3848 C C . SER A 1 475 ? 67.356 34.706 25.502 1.00 37.05 ? 511 SER A C 1 ATOM 3849 O O . SER A 1 475 ? 67.370 34.818 26.729 1.00 36.53 ? 511 SER A O 1 ATOM 3850 C CB . SER A 1 475 ? 68.958 33.257 24.297 1.00 37.57 ? 511 SER A CB 1 ATOM 3851 O OG . SER A 1 475 ? 69.086 32.429 25.439 1.00 41.38 ? 511 SER A OG 1 ATOM 3852 N N . LYS A 1 476 ? 66.235 34.563 24.807 1.00 36.91 ? 512 LYS A N 1 ATOM 3853 C CA . LYS A 1 476 ? 64.946 34.476 25.475 1.00 35.32 ? 512 LYS A CA 1 ATOM 3854 C C . LYS A 1 476 ? 64.235 33.173 25.151 1.00 36.97 ? 512 LYS A C 1 ATOM 3855 O O . LYS A 1 476 ? 64.070 32.824 23.986 1.00 40.73 ? 512 LYS A O 1 ATOM 3856 C CB . LYS A 1 476 ? 64.083 35.651 25.051 1.00 36.83 ? 512 LYS A CB 1 ATOM 3857 C CG . LYS A 1 476 ? 62.689 35.652 25.611 1.00 37.48 ? 512 LYS A CG 1 ATOM 3858 C CD . LYS A 1 476 ? 62.145 37.056 25.446 1.00 33.02 ? 512 LYS A CD 1 ATOM 3859 C CE . LYS A 1 476 ? 60.660 37.092 25.534 1.00 31.72 ? 512 LYS A CE 1 ATOM 3860 N NZ . LYS A 1 476 ? 60.210 38.481 25.245 1.00 32.81 ? 512 LYS A NZ 1 ATOM 3861 N N . LYS A 1 477 ? 63.818 32.450 26.182 1.00 33.53 ? 513 LYS A N 1 ATOM 3862 C CA . LYS A 1 477 ? 63.003 31.264 25.981 1.00 33.31 ? 513 LYS A CA 1 ATOM 3863 C C . LYS A 1 477 ? 61.556 31.592 26.329 1.00 33.53 ? 513 LYS A C 1 ATOM 3864 O O . LYS A 1 477 ? 61.282 32.207 27.363 1.00 32.20 ? 513 LYS A O 1 ATOM 3865 C CB . LYS A 1 477 ? 63.515 30.100 26.842 1.00 33.88 ? 513 LYS A CB 1 ATOM 3866 C CG . LYS A 1 477 ? 62.623 28.860 26.817 1.00 37.73 ? 513 LYS A CG 1 ATOM 3867 C CD . LYS A 1 477 ? 63.298 27.673 27.505 1.00 42.06 ? 513 LYS A CD 1 ATOM 3868 N N . LEU A 1 478 ? 60.635 31.194 25.459 1.00 27.92 ? 514 LEU A N 1 ATOM 3869 C CA . LEU A 1 478 ? 59.209 31.374 25.698 1.00 28.37 ? 514 LEU A CA 1 ATOM 3870 C C . LEU A 1 478 ? 58.580 29.999 25.617 1.00 38.28 ? 514 LEU A C 1 ATOM 3871 O O . LEU A 1 478 ? 58.687 29.332 24.587 1.00 32.81 ? 514 LEU A O 1 ATOM 3872 C CB . LEU A 1 478 ? 58.615 32.297 24.633 1.00 33.35 ? 514 LEU A CB 1 ATOM 3873 C CG . LEU A 1 478 ? 57.104 32.494 24.646 1.00 34.07 ? 514 LEU A CG 1 ATOM 3874 C CD1 . LEU A 1 478 ? 56.661 33.226 25.919 1.00 31.66 ? 514 LEU A CD1 1 ATOM 3875 C CD2 . LEU A 1 478 ? 56.663 33.262 23.419 1.00 33.31 ? 514 LEU A CD2 1 ATOM 3876 N N . ASP A 1 479 ? 57.956 29.553 26.703 1.00 34.98 ? 515 ASP A N 1 ATOM 3877 C CA . ASP A 1 479 ? 57.420 28.191 26.757 1.00 34.95 ? 515 ASP A CA 1 ATOM 3878 C C . ASP A 1 479 ? 56.276 28.131 27.765 1.00 35.78 ? 515 ASP A C 1 ATOM 3879 O O . ASP A 1 479 ? 55.817 29.161 28.254 1.00 31.32 ? 515 ASP A O 1 ATOM 3880 C CB . ASP A 1 479 ? 58.529 27.201 27.138 1.00 37.52 ? 515 ASP A CB 1 ATOM 3881 C CG . ASP A 1 479 ? 58.369 25.831 26.462 1.00 47.75 ? 515 ASP A CG 1 ATOM 3882 O OD1 . ASP A 1 479 ? 57.217 25.385 26.234 1.00 40.78 ? 515 ASP A OD1 1 ATOM 3883 O OD2 . ASP A 1 479 ? 59.407 25.200 26.158 1.00 48.43 ? 515 ASP A OD2 1 ATOM 3884 N N . PHE A 1 480 ? 55.805 26.933 28.084 1.00 35.55 ? 516 PHE A N 1 ATOM 3885 C CA . PHE A 1 480 ? 54.685 26.814 29.007 1.00 37.55 ? 516 PHE A CA 1 ATOM 3886 C C . PHE A 1 480 ? 54.840 25.631 29.953 1.00 40.94 ? 516 PHE A C 1 ATOM 3887 O O . PHE A 1 480 ? 55.543 24.670 29.642 1.00 42.93 ? 516 PHE A O 1 ATOM 3888 C CB . PHE A 1 480 ? 53.379 26.669 28.231 1.00 37.11 ? 516 PHE A CB 1 ATOM 3889 C CG . PHE A 1 480 ? 53.302 25.419 27.387 1.00 41.02 ? 516 PHE A CG 1 ATOM 3890 C CD1 . PHE A 1 480 ? 52.949 24.202 27.951 1.00 44.65 ? 516 PHE A CD1 1 ATOM 3891 C CD2 . PHE A 1 480 ? 53.557 25.470 26.023 1.00 42.38 ? 516 PHE A CD2 1 ATOM 3892 C CE1 . PHE A 1 480 ? 52.866 23.049 27.177 1.00 45.36 ? 516 PHE A CE1 1 ATOM 3893 C CE2 . PHE A 1 480 ? 53.477 24.320 25.243 1.00 48.50 ? 516 PHE A CE2 1 ATOM 3894 C CZ . PHE A 1 480 ? 53.130 23.109 25.828 1.00 44.22 ? 516 PHE A CZ 1 ATOM 3895 N N . ILE A 1 481 ? 54.182 25.710 31.106 1.00 35.86 ? 517 ILE A N 1 ATOM 3896 C CA . ILE A 1 481 ? 54.074 24.566 32.006 1.00 39.98 ? 517 ILE A CA 1 ATOM 3897 C C . ILE A 1 481 ? 52.601 24.223 32.173 1.00 44.13 ? 517 ILE A C 1 ATOM 3898 O O . ILE A 1 481 ? 51.739 25.078 32.001 1.00 45.64 ? 517 ILE A O 1 ATOM 3899 C CB . ILE A 1 481 ? 54.678 24.854 33.384 1.00 36.05 ? 517 ILE A CB 1 ATOM 3900 C CG1 . ILE A 1 481 ? 53.974 26.044 34.031 1.00 39.65 ? 517 ILE A CG1 1 ATOM 3901 C CG2 . ILE A 1 481 ? 56.168 25.110 33.264 1.00 41.19 ? 517 ILE A CG2 1 ATOM 3902 C CD1 . ILE A 1 481 ? 54.616 26.511 35.323 1.00 45.16 ? 517 ILE A CD1 1 ATOM 3903 N N . ILE A 1 482 ? 52.311 22.975 32.508 1.00 44.58 ? 518 ILE A N 1 ATOM 3904 C CA . ILE A 1 482 ? 50.933 22.536 32.616 1.00 47.97 ? 518 ILE A CA 1 ATOM 3905 C C . ILE A 1 482 ? 50.536 22.421 34.070 1.00 48.34 ? 518 ILE A C 1 ATOM 3906 O O . ILE A 1 482 ? 51.088 21.604 34.796 1.00 54.93 ? 518 ILE A O 1 ATOM 3907 C CB . ILE A 1 482 ? 50.733 21.175 31.943 1.00 48.74 ? 518 ILE A CB 1 ATOM 3908 C CG1 . ILE A 1 482 ? 51.226 21.230 30.497 1.00 49.76 ? 518 ILE A CG1 1 ATOM 3909 C CG2 . ILE A 1 482 ? 49.275 20.771 32.000 1.00 46.66 ? 518 ILE A CG2 1 ATOM 3910 C CD1 . ILE A 1 482 ? 51.028 19.932 29.731 1.00 59.14 ? 518 ILE A CD1 1 ATOM 3911 N N . LEU A 1 483 ? 49.593 23.255 34.497 1.00 49.80 ? 519 LEU A N 1 ATOM 3912 C CA . LEU A 1 483 ? 49.056 23.194 35.855 1.00 50.53 ? 519 LEU A CA 1 ATOM 3913 C C . LEU A 1 483 ? 47.576 22.857 35.784 1.00 53.73 ? 519 LEU A C 1 ATOM 3914 O O . LEU A 1 483 ? 46.808 23.562 35.123 1.00 50.89 ? 519 LEU A O 1 ATOM 3915 C CB . LEU A 1 483 ? 49.226 24.530 36.577 1.00 43.21 ? 519 LEU A CB 1 ATOM 3916 C CG . LEU A 1 483 ? 50.640 25.090 36.646 1.00 50.85 ? 519 LEU A CG 1 ATOM 3917 C CD1 . LEU A 1 483 ? 50.637 26.438 37.357 1.00 46.98 ? 519 LEU A CD1 1 ATOM 3918 C CD2 . LEU A 1 483 ? 51.570 24.106 37.351 1.00 55.51 ? 519 LEU A CD2 1 ATOM 3919 N N . ASN A 1 484 ? 47.177 21.784 36.464 1.00 53.18 ? 520 ASN A N 1 ATOM 3920 C CA . ASN A 1 484 ? 45.787 21.341 36.442 1.00 53.55 ? 520 ASN A CA 1 ATOM 3921 C C . ASN A 1 484 ? 45.260 21.225 35.024 1.00 54.95 ? 520 ASN A C 1 ATOM 3922 O O . ASN A 1 484 ? 44.157 21.679 34.720 1.00 58.71 ? 520 ASN A O 1 ATOM 3923 C CB . ASN A 1 484 ? 44.911 22.291 37.255 1.00 54.73 ? 520 ASN A CB 1 ATOM 3924 C CG . ASN A 1 484 ? 45.367 22.406 38.689 1.00 57.54 ? 520 ASN A CG 1 ATOM 3925 O OD1 . ASN A 1 484 ? 46.314 21.734 39.103 1.00 58.94 ? 520 ASN A OD1 1 ATOM 3926 N ND2 . ASN A 1 484 ? 44.706 23.271 39.455 1.00 62.08 ? 520 ASN A ND2 1 ATOM 3927 N N . GLU A 1 485 ? 46.071 20.630 34.156 1.00 56.46 ? 521 GLU A N 1 ATOM 3928 C CA . GLU A 1 485 ? 45.713 20.432 32.757 1.00 53.52 ? 521 GLU A CA 1 ATOM 3929 C C . GLU A 1 485 ? 45.433 21.724 31.975 1.00 56.54 ? 521 GLU A C 1 ATOM 3930 O O . GLU A 1 485 ? 44.807 21.686 30.912 1.00 54.78 ? 521 GLU A O 1 ATOM 3931 C CB . GLU A 1 485 ? 44.540 19.461 32.644 1.00 60.15 ? 521 GLU A CB 1 ATOM 3932 C CG . GLU A 1 485 ? 44.875 18.050 33.119 1.00 65.39 ? 521 GLU A CG 1 ATOM 3933 C CD . GLU A 1 485 ? 43.690 17.102 33.033 1.00 73.22 ? 521 GLU A CD 1 ATOM 3934 O OE1 . GLU A 1 485 ? 42.635 17.397 33.645 1.00 72.91 ? 521 GLU A OE1 1 ATOM 3935 O OE2 . GLU A 1 485 ? 43.816 16.061 32.348 1.00 74.33 ? 521 GLU A OE2 1 ATOM 3936 N N . THR A 1 486 ? 45.900 22.859 32.491 1.00 51.66 ? 522 THR A N 1 ATOM 3937 C CA . THR A 1 486 ? 45.878 24.104 31.716 1.00 50.14 ? 522 THR A CA 1 ATOM 3938 C C . THR A 1 486 ? 47.302 24.549 31.396 1.00 46.36 ? 522 THR A C 1 ATOM 3939 O O . THR A 1 486 ? 48.186 24.458 32.249 1.00 43.77 ? 522 THR A O 1 ATOM 3940 C CB . THR A 1 486 ? 45.162 25.257 32.462 1.00 46.58 ? 522 THR A CB 1 ATOM 3941 O OG1 . THR A 1 486 ? 43.794 24.911 32.691 1.00 49.19 ? 522 THR A OG1 1 ATOM 3942 C CG2 . THR A 1 486 ? 45.217 26.546 31.636 1.00 41.98 ? 522 THR A CG2 1 ATOM 3943 N N . LYS A 1 487 ? 47.523 25.027 30.174 1.00 39.57 ? 523 LYS A N 1 ATOM 3944 C CA . LYS A 1 487 ? 48.820 25.594 29.819 1.00 42.33 ? 523 LYS A CA 1 ATOM 3945 C C . LYS A 1 487 ? 48.976 27.015 30.356 1.00 40.07 ? 523 LYS A C 1 ATOM 3946 O O . LYS A 1 487 ? 48.092 27.861 30.173 1.00 37.35 ? 523 LYS A O 1 ATOM 3947 C CB . LYS A 1 487 ? 49.031 25.601 28.302 1.00 40.80 ? 523 LYS A CB 1 ATOM 3948 C CG . LYS A 1 487 ? 49.311 24.232 27.697 1.00 48.20 ? 523 LYS A CG 1 ATOM 3949 C CD . LYS A 1 487 ? 49.866 24.347 26.274 1.00 49.67 ? 523 LYS A CD 1 ATOM 3950 C CE . LYS A 1 487 ? 48.872 25.019 25.335 1.00 52.59 ? 523 LYS A CE 1 ATOM 3951 N NZ . LYS A 1 487 ? 49.352 25.113 23.914 1.00 57.43 ? 523 LYS A NZ 1 ATOM 3952 N N . PHE A 1 488 ? 50.106 27.272 31.009 1.00 33.30 ? 524 PHE A N 1 ATOM 3953 C CA . PHE A 1 488 ? 50.443 28.618 31.457 1.00 32.16 ? 524 PHE A CA 1 ATOM 3954 C C . PHE A 1 488 ? 51.810 28.988 30.925 1.00 32.99 ? 524 PHE A C 1 ATOM 3955 O O . PHE A 1 488 ? 52.758 28.230 31.081 1.00 35.50 ? 524 PHE A O 1 ATOM 3956 C CB . PHE A 1 488 ? 50.397 28.706 32.978 1.00 35.20 ? 524 PHE A CB 1 ATOM 3957 C CG . PHE A 1 488 ? 49.008 28.563 33.538 1.00 36.66 ? 524 PHE A CG 1 ATOM 3958 C CD1 . PHE A 1 488 ? 48.108 29.614 33.462 1.00 32.19 ? 524 PHE A CD1 1 ATOM 3959 C CD2 . PHE A 1 488 ? 48.597 27.374 34.121 1.00 41.51 ? 524 PHE A CD2 1 ATOM 3960 C CE1 . PHE A 1 488 ? 46.829 29.482 33.956 1.00 33.96 ? 524 PHE A CE1 1 ATOM 3961 C CE2 . PHE A 1 488 ? 47.323 27.241 34.624 1.00 39.89 ? 524 PHE A CE2 1 ATOM 3962 C CZ . PHE A 1 488 ? 46.436 28.297 34.537 1.00 36.52 ? 524 PHE A CZ 1 ATOM 3963 N N . TRP A 1 489 ? 51.899 30.150 30.289 1.00 29.04 ? 525 TRP A N 1 ATOM 3964 C CA . TRP A 1 489 ? 53.090 30.538 29.535 1.00 29.74 ? 525 TRP A CA 1 ATOM 3965 C C . TRP A 1 489 ? 54.080 31.339 30.375 1.00 30.24 ? 525 TRP A C 1 ATOM 3966 O O . TRP A 1 489 ? 53.682 32.135 31.231 1.00 27.84 ? 525 TRP A O 1 ATOM 3967 C CB . TRP A 1 489 ? 52.679 31.352 28.305 1.00 27.61 ? 525 TRP A CB 1 ATOM 3968 C CG . TRP A 1 489 ? 52.006 30.502 27.250 1.00 32.62 ? 525 TRP A CG 1 ATOM 3969 C CD1 . TRP A 1 489 ? 50.703 30.077 27.233 1.00 30.72 ? 525 TRP A CD1 1 ATOM 3970 C CD2 . TRP A 1 489 ? 52.622 29.958 26.071 1.00 32.13 ? 525 TRP A CD2 1 ATOM 3971 N NE1 . TRP A 1 489 ? 50.475 29.302 26.107 1.00 33.16 ? 525 TRP A NE1 1 ATOM 3972 C CE2 . TRP A 1 489 ? 51.636 29.213 25.384 1.00 31.53 ? 525 TRP A CE2 1 ATOM 3973 C CE3 . TRP A 1 489 ? 53.912 30.029 25.535 1.00 29.20 ? 525 TRP A CE3 1 ATOM 3974 C CZ2 . TRP A 1 489 ? 51.902 28.549 24.187 1.00 34.10 ? 525 TRP A CZ2 1 ATOM 3975 C CZ3 . TRP A 1 489 ? 54.174 29.372 24.347 1.00 35.18 ? 525 TRP A CZ3 1 ATOM 3976 C CH2 . TRP A 1 489 ? 53.172 28.640 23.684 1.00 34.90 ? 525 TRP A CH2 1 ATOM 3977 N N . TYR A 1 490 ? 55.366 31.138 30.120 1.00 27.14 ? 526 TYR A N 1 ATOM 3978 C CA . TYR A 1 490 ? 56.400 31.880 30.835 1.00 28.74 ? 526 TYR A CA 1 ATOM 3979 C C . TYR A 1 490 ? 57.501 32.229 29.871 1.00 31.72 ? 526 TYR A C 1 ATOM 3980 O O . TYR A 1 490 ? 57.668 31.574 28.831 1.00 27.94 ? 526 TYR A O 1 ATOM 3981 C CB . TYR A 1 490 ? 56.964 31.066 32.012 1.00 28.10 ? 526 TYR A CB 1 ATOM 3982 C CG . TYR A 1 490 ? 57.787 29.864 31.596 1.00 33.88 ? 526 TYR A CG 1 ATOM 3983 C CD1 . TYR A 1 490 ? 59.141 29.991 31.314 1.00 33.12 ? 526 TYR A CD1 1 ATOM 3984 C CD2 . TYR A 1 490 ? 57.213 28.601 31.490 1.00 34.94 ? 526 TYR A CD2 1 ATOM 3985 C CE1 . TYR A 1 490 ? 59.895 28.908 30.930 1.00 34.37 ? 526 TYR A CE1 1 ATOM 3986 C CE2 . TYR A 1 490 ? 57.964 27.506 31.103 1.00 36.68 ? 526 TYR A CE2 1 ATOM 3987 C CZ . TYR A 1 490 ? 59.303 27.667 30.821 1.00 38.63 ? 526 TYR A CZ 1 ATOM 3988 O OH . TYR A 1 490 ? 60.063 26.586 30.435 1.00 42.22 ? 526 TYR A OH 1 ATOM 3989 N N . GLN A 1 491 ? 58.247 33.273 30.195 1.00 26.90 ? 527 GLN A N 1 ATOM 3990 C CA . GLN A 1 491 ? 59.486 33.542 29.488 1.00 25.79 ? 527 GLN A CA 1 ATOM 3991 C C . GLN A 1 491 ? 60.686 33.566 30.442 1.00 31.85 ? 527 GLN A C 1 ATOM 3992 O O . GLN A 1 491 ? 60.546 33.867 31.641 1.00 25.90 ? 527 GLN A O 1 ATOM 3993 C CB . GLN A 1 491 ? 59.390 34.848 28.728 1.00 26.73 ? 527 GLN A CB 1 ATOM 3994 C CG . GLN A 1 491 ? 59.244 36.068 29.606 1.00 28.79 ? 527 GLN A CG 1 ATOM 3995 C CD . GLN A 1 491 ? 59.340 37.318 28.779 1.00 32.08 ? 527 GLN A CD 1 ATOM 3996 O OE1 . GLN A 1 491 ? 58.671 37.435 27.757 1.00 27.94 ? 527 GLN A OE1 1 ATOM 3997 N NE2 . GLN A 1 491 ? 60.205 38.241 29.181 1.00 31.22 ? 527 GLN A NE2 1 ATOM 3998 N N . MET A 1 492 ? 61.859 33.242 29.905 1.00 30.02 ? 528 MET A N 1 ATOM 3999 C CA . MET A 1 492 ? 63.122 33.403 30.623 1.00 28.26 ? 528 MET A CA 1 ATOM 4000 C C . MET A 1 492 ? 64.123 34.189 29.787 1.00 32.07 ? 528 MET A C 1 ATOM 4001 O O . MET A 1 492 ? 64.376 33.842 28.645 1.00 32.63 ? 528 MET A O 1 ATOM 4002 C CB . MET A 1 492 ? 63.711 32.039 31.009 1.00 31.67 ? 528 MET A CB 1 ATOM 4003 C CG . MET A 1 492 ? 62.968 31.367 32.157 1.00 36.57 ? 528 MET A CG 1 ATOM 4004 S SD . MET A 1 492 ? 63.597 29.745 32.650 1.00 40.92 ? 528 MET A SD 1 ATOM 4005 C CE . MET A 1 492 ? 63.511 28.899 31.077 1.00 51.41 ? 528 MET A CE 1 ATOM 4006 N N . ILE A 1 493 ? 64.667 35.267 30.343 1.00 30.08 ? 529 ILE A N 1 ATOM 4007 C CA . ILE A 1 493 ? 65.857 35.878 29.780 1.00 29.41 ? 529 ILE A CA 1 ATOM 4008 C C . ILE A 1 493 ? 67.068 35.096 30.309 1.00 32.58 ? 529 ILE A C 1 ATOM 4009 O O . ILE A 1 493 ? 67.385 35.169 31.494 1.00 31.16 ? 529 ILE A O 1 ATOM 4010 C CB . ILE A 1 493 ? 65.985 37.338 30.205 1.00 33.14 ? 529 ILE A CB 1 ATOM 4011 C CG1 . ILE A 1 493 ? 64.656 38.068 30.012 1.00 32.63 ? 529 ILE A CG1 1 ATOM 4012 C CG2 . ILE A 1 493 ? 67.111 38.023 29.440 1.00 28.26 ? 529 ILE A CG2 1 ATOM 4013 C CD1 . ILE A 1 493 ? 64.123 37.933 28.603 1.00 33.78 ? 529 ILE A CD1 1 ATOM 4014 N N . LEU A 1 494 ? 67.731 34.337 29.434 1.00 32.16 ? 530 LEU A N 1 ATOM 4015 C CA . LEU A 1 494 ? 68.840 33.471 29.834 1.00 32.34 ? 530 LEU A CA 1 ATOM 4016 C C . LEU A 1 494 ? 70.189 34.128 29.552 1.00 32.85 ? 530 LEU A C 1 ATOM 4017 O O . LEU A 1 494 ? 70.355 34.807 28.547 1.00 35.23 ? 530 LEU A O 1 ATOM 4018 C CB . LEU A 1 494 ? 68.760 32.125 29.108 1.00 33.03 ? 530 LEU A CB 1 ATOM 4019 C CG . LEU A 1 494 ? 67.457 31.359 29.298 1.00 32.40 ? 530 LEU A CG 1 ATOM 4020 C CD1 . LEU A 1 494 ? 67.258 30.342 28.178 1.00 34.74 ? 530 LEU A CD1 1 ATOM 4021 C CD2 . LEU A 1 494 ? 67.435 30.679 30.657 1.00 31.17 ? 530 LEU A CD2 1 ATOM 4022 N N . PRO A 1 495 ? 71.163 33.939 30.449 1.00 34.17 ? 531 PRO A N 1 ATOM 4023 C CA . PRO A 1 495 ? 72.490 34.539 30.275 1.00 31.93 ? 531 PRO A CA 1 ATOM 4024 C C . PRO A 1 495 ? 73.195 33.978 29.040 1.00 35.21 ? 531 PRO A C 1 ATOM 4025 O O . PRO A 1 495 ? 72.892 32.870 28.626 1.00 35.88 ? 531 PRO A O 1 ATOM 4026 C CB . PRO A 1 495 ? 73.230 34.105 31.546 1.00 32.53 ? 531 PRO A CB 1 ATOM 4027 C CG . PRO A 1 495 ? 72.130 33.894 32.549 1.00 36.87 ? 531 PRO A CG 1 ATOM 4028 C CD . PRO A 1 495 ? 71.019 33.281 31.758 1.00 31.14 ? 531 PRO A CD 1 ATOM 4029 N N . PRO A 1 496 ? 74.119 34.742 28.456 1.00 38.15 ? 532 PRO A N 1 ATOM 4030 C CA . PRO A 1 496 ? 74.879 34.263 27.289 1.00 44.93 ? 532 PRO A CA 1 ATOM 4031 C C . PRO A 1 496 ? 75.568 32.926 27.575 1.00 44.96 ? 532 PRO A C 1 ATOM 4032 O O . PRO A 1 496 ? 75.922 32.663 28.726 1.00 44.10 ? 532 PRO A O 1 ATOM 4033 C CB . PRO A 1 496 ? 75.925 35.365 27.070 1.00 41.77 ? 532 PRO A CB 1 ATOM 4034 C CG . PRO A 1 496 ? 75.936 36.170 28.348 1.00 40.95 ? 532 PRO A CG 1 ATOM 4035 C CD . PRO A 1 496 ? 74.548 36.079 28.895 1.00 35.98 ? 532 PRO A CD 1 ATOM 4036 N N . HIS A 1 497 ? 75.753 32.099 26.546 1.00 47.48 ? 533 HIS A N 1 ATOM 4037 C CA . HIS A 1 497 ? 76.394 30.790 26.708 1.00 48.16 ? 533 HIS A CA 1 ATOM 4038 C C . HIS A 1 497 ? 75.726 30.011 27.829 1.00 48.17 ? 533 HIS A C 1 ATOM 4039 O O . HIS A 1 497 ? 76.393 29.419 28.677 1.00 46.85 ? 533 HIS A O 1 ATOM 4040 C CB . HIS A 1 497 ? 77.890 30.944 26.987 1.00 46.25 ? 533 HIS A CB 1 ATOM 4041 C CG . HIS A 1 497 ? 78.573 31.882 26.047 1.00 51.43 ? 533 HIS A CG 1 ATOM 4042 N ND1 . HIS A 1 497 ? 79.352 32.933 26.479 1.00 52.70 ? 533 HIS A ND1 1 ATOM 4043 C CD2 . HIS A 1 497 ? 78.568 31.946 24.694 1.00 52.18 ? 533 HIS A CD2 1 ATOM 4044 C CE1 . HIS A 1 497 ? 79.811 33.596 25.432 1.00 50.11 ? 533 HIS A CE1 1 ATOM 4045 N NE2 . HIS A 1 497 ? 79.347 33.019 24.337 1.00 56.70 ? 533 HIS A NE2 1 ATOM 4046 N N . PHE A 1 498 ? 74.400 30.019 27.820 1.00 44.71 ? 534 PHE A N 1 ATOM 4047 C CA . PHE A 1 498 ? 73.625 29.299 28.815 1.00 45.39 ? 534 PHE A CA 1 ATOM 4048 C C . PHE A 1 498 ? 73.984 27.813 28.876 1.00 47.43 ? 534 PHE A C 1 ATOM 4049 O O . PHE A 1 498 ? 74.098 27.142 27.850 1.00 48.40 ? 534 PHE A O 1 ATOM 4050 C CB . PHE A 1 498 ? 72.135 29.470 28.541 1.00 41.80 ? 534 PHE A CB 1 ATOM 4051 C CG . PHE A 1 498 ? 71.265 28.738 29.507 1.00 43.07 ? 534 PHE A CG 1 ATOM 4052 C CD1 . PHE A 1 498 ? 71.240 29.105 30.843 1.00 41.31 ? 534 PHE A CD1 1 ATOM 4053 C CD2 . PHE A 1 498 ? 70.473 27.681 29.083 1.00 41.77 ? 534 PHE A CD2 1 ATOM 4054 C CE1 . PHE A 1 498 ? 70.438 28.427 31.743 1.00 42.25 ? 534 PHE A CE1 1 ATOM 4055 C CE2 . PHE A 1 498 ? 69.666 27.003 29.977 1.00 43.88 ? 534 PHE A CE2 1 ATOM 4056 C CZ . PHE A 1 498 ? 69.650 27.372 31.303 1.00 43.11 ? 534 PHE A CZ 1 ATOM 4057 N N . ASP A 1 499 ? 74.141 27.310 30.095 1.00 48.32 ? 535 ASP A N 1 ATOM 4058 C CA . ASP A 1 499 ? 74.538 25.928 30.337 1.00 50.44 ? 535 ASP A CA 1 ATOM 4059 C C . ASP A 1 499 ? 73.578 25.273 31.328 1.00 50.77 ? 535 ASP A C 1 ATOM 4060 O O . ASP A 1 499 ? 73.579 25.612 32.517 1.00 51.56 ? 535 ASP A O 1 ATOM 4061 C CB . ASP A 1 499 ? 75.957 25.911 30.912 1.00 54.05 ? 535 ASP A CB 1 ATOM 4062 C CG . ASP A 1 499 ? 76.596 24.534 30.872 1.00 55.84 ? 535 ASP A CG 1 ATOM 4063 O OD1 . ASP A 1 499 ? 75.870 23.529 30.699 1.00 56.18 ? 535 ASP A OD1 1 ATOM 4064 O OD2 . ASP A 1 499 ? 77.834 24.464 31.025 1.00 59.67 ? 535 ASP A OD2 1 ATOM 4065 N N . LYS A 1 500 ? 72.767 24.332 30.853 1.00 48.72 ? 536 LYS A N 1 ATOM 4066 C CA . LYS A 1 500 ? 71.743 23.721 31.699 1.00 46.83 ? 536 LYS A CA 1 ATOM 4067 C C . LYS A 1 500 ? 72.304 22.810 32.796 1.00 52.16 ? 536 LYS A C 1 ATOM 4068 O O . LYS A 1 500 ? 71.581 22.410 33.713 1.00 50.48 ? 536 LYS A O 1 ATOM 4069 C CB . LYS A 1 500 ? 70.727 22.966 30.848 1.00 50.84 ? 536 LYS A CB 1 ATOM 4070 C CG . LYS A 1 500 ? 71.359 22.047 29.814 1.00 60.85 ? 536 LYS A CG 1 ATOM 4071 C CD . LYS A 1 500 ? 70.307 21.512 28.849 1.00 72.02 ? 536 LYS A CD 1 ATOM 4072 C CE . LYS A 1 500 ? 70.932 20.744 27.692 1.00 75.19 ? 536 LYS A CE 1 ATOM 4073 N NZ . LYS A 1 500 ? 69.902 20.421 26.660 1.00 75.73 ? 536 LYS A NZ 1 ATOM 4074 N N . SER A 1 501 ? 73.589 22.483 32.706 1.00 52.40 ? 537 SER A N 1 ATOM 4075 C CA . SER A 1 501 ? 74.238 21.679 33.738 1.00 55.18 ? 537 SER A CA 1 ATOM 4076 C C . SER A 1 501 ? 74.686 22.560 34.900 1.00 56.79 ? 537 SER A C 1 ATOM 4077 O O . SER A 1 501 ? 75.144 22.064 35.929 1.00 58.95 ? 537 SER A O 1 ATOM 4078 C CB . SER A 1 501 ? 75.439 20.924 33.166 1.00 58.22 ? 537 SER A CB 1 ATOM 4079 O OG . SER A 1 501 ? 76.514 21.810 32.884 1.00 57.76 ? 537 SER A OG 1 ATOM 4080 N N . LYS A 1 502 ? 74.560 23.870 34.730 1.00 54.53 ? 538 LYS A N 1 ATOM 4081 C CA . LYS A 1 502 ? 74.916 24.803 35.792 1.00 52.99 ? 538 LYS A CA 1 ATOM 4082 C C . LYS A 1 502 ? 73.686 25.230 36.589 1.00 49.96 ? 538 LYS A C 1 ATOM 4083 O O . LYS A 1 502 ? 72.551 25.002 36.172 1.00 49.76 ? 538 LYS A O 1 ATOM 4084 C CB . LYS A 1 502 ? 75.620 26.035 35.219 1.00 51.29 ? 538 LYS A CB 1 ATOM 4085 C CG . LYS A 1 502 ? 76.850 25.719 34.382 1.00 55.80 ? 538 LYS A CG 1 ATOM 4086 C CD . LYS A 1 502 ? 77.725 26.957 34.224 1.00 59.70 ? 538 LYS A CD 1 ATOM 4087 C CE . LYS A 1 502 ? 79.009 26.641 33.466 1.00 68.32 ? 538 LYS A CE 1 ATOM 4088 N NZ . LYS A 1 502 ? 79.997 27.759 33.546 1.00 70.43 ? 538 LYS A NZ 1 ATOM 4089 N N . LYS A 1 503 ? 73.919 25.843 37.744 1.00 47.20 ? 539 LYS A N 1 ATOM 4090 C CA . LYS A 1 503 ? 72.842 26.401 38.551 1.00 44.44 ? 539 LYS A CA 1 ATOM 4091 C C . LYS A 1 503 ? 72.949 27.924 38.504 1.00 47.71 ? 539 LYS A C 1 ATOM 4092 O O . LYS A 1 503 ? 74.020 28.480 38.760 1.00 48.37 ? 539 LYS A O 1 ATOM 4093 C CB . LYS A 1 503 ? 72.945 25.911 39.999 1.00 49.35 ? 539 LYS A CB 1 ATOM 4094 C CG . LYS A 1 503 ? 72.761 24.408 40.183 1.00 50.14 ? 539 LYS A CG 1 ATOM 4095 C CD . LYS A 1 503 ? 71.288 24.027 40.209 1.00 50.76 ? 539 LYS A CD 1 ATOM 4096 C CE . LYS A 1 503 ? 71.087 22.562 40.596 1.00 55.54 ? 539 LYS A CE 1 ATOM 4097 N NZ . LYS A 1 503 ? 69.639 22.223 40.727 1.00 58.59 ? 539 LYS A NZ 1 ATOM 4098 N N . TYR A 1 504 ? 71.851 28.597 38.159 1.00 39.43 ? 540 TYR A N 1 ATOM 4099 C CA . TYR A 1 504 ? 71.845 30.050 38.122 1.00 34.53 ? 540 TYR A CA 1 ATOM 4100 C C . TYR A 1 504 ? 70.889 30.629 39.169 1.00 35.61 ? 540 TYR A C 1 ATOM 4101 O O . TYR A 1 504 ? 69.878 30.017 39.506 1.00 35.60 ? 540 TYR A O 1 ATOM 4102 C CB . TYR A 1 504 ? 71.431 30.559 36.744 1.00 36.01 ? 540 TYR A CB 1 ATOM 4103 C CG . TYR A 1 504 ? 72.333 30.157 35.601 1.00 39.59 ? 540 TYR A CG 1 ATOM 4104 C CD1 . TYR A 1 504 ? 72.189 28.923 34.981 1.00 38.60 ? 540 TYR A CD1 1 ATOM 4105 C CD2 . TYR A 1 504 ? 73.306 31.023 35.121 1.00 37.39 ? 540 TYR A CD2 1 ATOM 4106 C CE1 . TYR A 1 504 ? 72.999 28.553 33.930 1.00 42.66 ? 540 TYR A CE1 1 ATOM 4107 C CE2 . TYR A 1 504 ? 74.119 30.665 34.058 1.00 40.35 ? 540 TYR A CE2 1 ATOM 4108 C CZ . TYR A 1 504 ? 73.960 29.426 33.467 1.00 43.91 ? 540 TYR A CZ 1 ATOM 4109 O OH . TYR A 1 504 ? 74.771 29.058 32.410 1.00 44.96 ? 540 TYR A OH 1 ATOM 4110 N N . PRO A 1 505 ? 71.212 31.816 39.693 1.00 33.90 ? 541 PRO A N 1 ATOM 4111 C CA . PRO A 1 505 ? 70.224 32.517 40.514 1.00 31.55 ? 541 PRO A CA 1 ATOM 4112 C C . PRO A 1 505 ? 69.075 32.950 39.613 1.00 32.40 ? 541 PRO A C 1 ATOM 4113 O O . PRO A 1 505 ? 69.326 33.209 38.441 1.00 35.39 ? 541 PRO A O 1 ATOM 4114 C CB . PRO A 1 505 ? 70.987 33.751 41.021 1.00 34.53 ? 541 PRO A CB 1 ATOM 4115 C CG . PRO A 1 505 ? 72.095 33.960 40.065 1.00 34.07 ? 541 PRO A CG 1 ATOM 4116 C CD . PRO A 1 505 ? 72.441 32.602 39.486 1.00 37.60 ? 541 PRO A CD 1 ATOM 4117 N N . LEU A 1 506 ? 67.853 33.013 40.136 1.00 31.76 ? 542 LEU A N 1 ATOM 4118 C CA . LEU A 1 506 ? 66.703 33.412 39.334 1.00 32.71 ? 542 LEU A CA 1 ATOM 4119 C C . LEU A 1 506 ? 65.935 34.578 39.958 1.00 32.54 ? 542 LEU A C 1 ATOM 4120 O O . LEU A 1 506 ? 65.572 34.522 41.130 1.00 32.65 ? 542 LEU A O 1 ATOM 4121 C CB . LEU A 1 506 ? 65.757 32.227 39.154 1.00 31.69 ? 542 LEU A CB 1 ATOM 4122 C CG . LEU A 1 506 ? 64.599 32.523 38.197 1.00 32.61 ? 542 LEU A CG 1 ATOM 4123 C CD1 . LEU A 1 506 ? 64.375 31.345 37.262 1.00 33.58 ? 542 LEU A CD1 1 ATOM 4124 C CD2 . LEU A 1 506 ? 63.334 32.845 38.972 1.00 29.99 ? 542 LEU A CD2 1 ATOM 4125 N N . LEU A 1 507 ? 65.695 35.623 39.167 1.00 30.10 ? 543 LEU A N 1 ATOM 4126 C CA . LEU A 1 507 ? 64.823 36.725 39.560 1.00 27.05 ? 543 LEU A CA 1 ATOM 4127 C C . LEU A 1 507 ? 63.463 36.585 38.853 1.00 30.77 ? 543 LEU A C 1 ATOM 4128 O O . LEU A 1 507 ? 63.379 36.574 37.624 1.00 30.09 ? 543 LEU A O 1 ATOM 4129 C CB . LEU A 1 507 ? 65.480 38.063 39.194 1.00 26.55 ? 543 LEU A CB 1 ATOM 4130 C CG . LEU A 1 507 ? 64.671 39.354 39.304 1.00 28.69 ? 543 LEU A CG 1 ATOM 4131 C CD1 . LEU A 1 507 ? 64.222 39.601 40.751 1.00 25.84 ? 543 LEU A CD1 1 ATOM 4132 C CD2 . LEU A 1 507 ? 65.465 40.553 38.797 1.00 28.40 ? 543 LEU A CD2 1 ATOM 4133 N N . LEU A 1 508 ? 62.389 36.469 39.619 1.00 28.86 ? 544 LEU A N 1 ATOM 4134 C CA . LEU A 1 508 ? 61.063 36.424 39.014 1.00 25.82 ? 544 LEU A CA 1 ATOM 4135 C C . LEU A 1 508 ? 60.541 37.845 38.897 1.00 27.22 ? 544 LEU A C 1 ATOM 4136 O O . LEU A 1 508 ? 60.311 38.533 39.903 1.00 28.40 ? 544 LEU A O 1 ATOM 4137 C CB . LEU A 1 508 ? 60.122 35.558 39.853 1.00 27.62 ? 544 LEU A CB 1 ATOM 4138 C CG . LEU A 1 508 ? 58.713 35.333 39.326 1.00 30.28 ? 544 LEU A CG 1 ATOM 4139 C CD1 . LEU A 1 508 ? 58.747 34.618 37.978 1.00 28.96 ? 544 LEU A CD1 1 ATOM 4140 C CD2 . LEU A 1 508 ? 57.925 34.530 40.333 1.00 33.67 ? 544 LEU A CD2 1 ATOM 4141 N N . ASP A 1 509 ? 60.390 38.288 37.660 1.00 25.56 ? 545 ASP A N 1 ATOM 4142 C CA . ASP A 1 509 ? 59.908 39.623 37.324 1.00 25.70 ? 545 ASP A CA 1 ATOM 4143 C C . ASP A 1 509 ? 58.382 39.571 37.183 1.00 29.94 ? 545 ASP A C 1 ATOM 4144 O O . ASP A 1 509 ? 57.846 38.920 36.276 1.00 26.17 ? 545 ASP A O 1 ATOM 4145 C CB . ASP A 1 509 ? 60.605 40.097 36.033 1.00 27.21 ? 545 ASP A CB 1 ATOM 4146 C CG . ASP A 1 509 ? 60.037 41.401 35.482 1.00 33.36 ? 545 ASP A CG 1 ATOM 4147 O OD1 . ASP A 1 509 ? 59.035 41.912 36.031 1.00 33.98 ? 545 ASP A OD1 1 ATOM 4148 O OD2 . ASP A 1 509 ? 60.586 41.901 34.472 1.00 34.14 ? 545 ASP A OD2 1 ATOM 4149 N N . VAL A 1 510 ? 57.685 40.260 38.086 1.00 25.30 ? 546 VAL A N 1 ATOM 4150 C CA . VAL A 1 510 ? 56.247 40.105 38.221 1.00 26.25 ? 546 VAL A CA 1 ATOM 4151 C C . VAL A 1 510 ? 55.443 41.350 37.872 1.00 28.37 ? 546 VAL A C 1 ATOM 4152 O O . VAL A 1 510 ? 55.786 42.457 38.291 1.00 26.06 ? 546 VAL A O 1 ATOM 4153 C CB . VAL A 1 510 ? 55.892 39.729 39.686 1.00 28.05 ? 546 VAL A CB 1 ATOM 4154 C CG1 . VAL A 1 510 ? 54.394 39.620 39.853 1.00 30.34 ? 546 VAL A CG1 1 ATOM 4155 C CG2 . VAL A 1 510 ? 56.567 38.424 40.069 1.00 29.31 ? 546 VAL A CG2 1 ATOM 4156 N N . TYR A 1 511 ? 54.368 41.168 37.105 1.00 26.40 ? 547 TYR A N 1 ATOM 4157 C CA . TYR A 1 511 ? 53.304 42.164 37.079 1.00 26.21 ? 547 TYR A CA 1 ATOM 4158 C C . TYR A 1 511 ? 52.003 41.499 37.503 1.00 29.23 ? 547 TYR A C 1 ATOM 4159 O O . TYR A 1 511 ? 51.543 41.699 38.625 1.00 28.54 ? 547 TYR A O 1 ATOM 4160 C CB . TYR A 1 511 ? 53.165 42.868 35.731 1.00 22.88 ? 547 TYR A CB 1 ATOM 4161 C CG . TYR A 1 511 ? 52.164 43.994 35.803 1.00 27.83 ? 547 TYR A CG 1 ATOM 4162 C CD1 . TYR A 1 511 ? 52.476 45.194 36.435 1.00 26.97 ? 547 TYR A CD1 1 ATOM 4163 C CD2 . TYR A 1 511 ? 50.891 43.850 35.272 1.00 27.59 ? 547 TYR A CD2 1 ATOM 4164 C CE1 . TYR A 1 511 ? 51.540 46.223 36.517 1.00 29.91 ? 547 TYR A CE1 1 ATOM 4165 C CE2 . TYR A 1 511 ? 49.958 44.868 35.347 1.00 26.26 ? 547 TYR A CE2 1 ATOM 4166 C CZ . TYR A 1 511 ? 50.281 46.045 35.974 1.00 27.94 ? 547 TYR A CZ 1 ATOM 4167 O OH . TYR A 1 511 ? 49.334 47.045 36.036 1.00 31.67 ? 547 TYR A OH 1 ATOM 4168 N N . ALA A 1 512 ? 51.412 40.703 36.616 1.00 28.35 ? 548 ALA A N 1 ATOM 4169 C CA . ALA A 1 512 ? 50.340 39.796 37.015 1.00 26.40 ? 548 ALA A CA 1 ATOM 4170 C C . ALA A 1 512 ? 48.986 40.458 37.305 1.00 24.84 ? 548 ALA A C 1 ATOM 4171 O O . ALA A 1 512 ? 48.100 39.829 37.872 1.00 27.44 ? 548 ALA A O 1 ATOM 4172 C CB . ALA A 1 512 ? 50.785 38.958 38.219 1.00 26.35 ? 548 ALA A CB 1 ATOM 4173 N N . GLY A 1 513 ? 48.813 41.711 36.902 1.00 25.42 ? 549 GLY A N 1 ATOM 4174 C CA . GLY A 1 513 ? 47.525 42.360 37.052 1.00 26.42 ? 549 GLY A CA 1 ATOM 4175 C C . GLY A 1 513 ? 46.527 41.721 36.101 1.00 30.41 ? 549 GLY A C 1 ATOM 4176 O O . GLY A 1 513 ? 46.922 40.993 35.184 1.00 26.17 ? 549 GLY A O 1 ATOM 4177 N N . PRO A 1 514 ? 45.233 41.990 36.305 1.00 28.25 ? 550 PRO A N 1 ATOM 4178 C CA . PRO A 1 514 ? 44.210 41.388 35.440 1.00 29.38 ? 550 PRO A CA 1 ATOM 4179 C C . PRO A 1 514 ? 44.422 41.739 33.978 1.00 29.83 ? 550 PRO A C 1 ATOM 4180 O O . PRO A 1 514 ? 44.597 42.913 33.643 1.00 25.17 ? 550 PRO A O 1 ATOM 4181 C CB . PRO A 1 514 ? 42.908 42.006 35.949 1.00 29.98 ? 550 PRO A CB 1 ATOM 4182 C CG . PRO A 1 514 ? 43.206 42.413 37.364 1.00 28.13 ? 550 PRO A CG 1 ATOM 4183 C CD . PRO A 1 514 ? 44.645 42.833 37.363 1.00 25.91 ? 550 PRO A CD 1 ATOM 4184 N N . CYS A 1 515 ? 44.404 40.709 33.135 1.00 27.83 ? 551 CYS A N 1 ATOM 4185 C CA . CYS A 1 515 ? 44.585 40.843 31.690 1.00 29.51 ? 551 CYS A CA 1 ATOM 4186 C C . CYS A 1 515 ? 45.992 41.314 31.318 1.00 30.98 ? 551 CYS A C 1 ATOM 4187 O O . CYS A 1 515 ? 46.194 41.919 30.269 1.00 33.65 ? 551 CYS A O 1 ATOM 4188 C CB . CYS A 1 515 ? 43.523 41.750 31.065 1.00 30.22 ? 551 CYS A CB 1 ATOM 4189 S SG . CYS A 1 515 ? 43.335 41.491 29.249 1.00 33.18 ? 551 CYS A SG 1 ATOM 4190 N N . SER A 1 516 ? 46.965 41.021 32.179 1.00 26.97 ? 552 SER A N 1 ATOM 4191 C CA . SER A 1 516 ? 48.355 41.302 31.865 1.00 26.47 ? 552 SER A CA 1 ATOM 4192 C C . SER A 1 516 ? 48.947 40.156 31.052 1.00 27.95 ? 552 SER A C 1 ATOM 4193 O O . SER A 1 516 ? 48.412 39.052 31.029 1.00 28.08 ? 552 SER A O 1 ATOM 4194 C CB . SER A 1 516 ? 49.174 41.485 33.144 1.00 29.12 ? 552 SER A CB 1 ATOM 4195 O OG . SER A 1 516 ? 49.325 40.248 33.813 1.00 30.80 ? 552 SER A OG 1 ATOM 4196 N N . GLN A 1 517 ? 50.067 40.424 30.400 1.00 27.26 ? 553 GLN A N 1 ATOM 4197 C CA . GLN A 1 517 ? 50.814 39.377 29.738 1.00 29.82 ? 553 GLN A CA 1 ATOM 4198 C C . GLN A 1 517 ? 52.279 39.721 29.852 1.00 29.89 ? 553 GLN A C 1 ATOM 4199 O O . GLN A 1 517 ? 52.727 40.697 29.250 1.00 25.30 ? 553 GLN A O 1 ATOM 4200 C CB . GLN A 1 517 ? 50.415 39.316 28.267 1.00 27.32 ? 553 GLN A CB 1 ATOM 4201 C CG . GLN A 1 517 ? 51.128 38.258 27.471 1.00 28.90 ? 553 GLN A CG 1 ATOM 4202 C CD . GLN A 1 517 ? 50.556 38.135 26.067 1.00 29.72 ? 553 GLN A CD 1 ATOM 4203 O OE1 . GLN A 1 517 ? 50.774 38.999 25.213 1.00 28.37 ? 553 GLN A OE1 1 ATOM 4204 N NE2 . GLN A 1 517 ? 49.818 37.058 25.825 1.00 28.58 ? 553 GLN A NE2 1 ATOM 4205 N N . LYS A 1 518 ? 53.024 38.928 30.622 1.00 26.12 ? 554 LYS A N 1 ATOM 4206 C CA . LYS A 1 518 ? 54.456 39.162 30.792 1.00 29.70 ? 554 LYS A CA 1 ATOM 4207 C C . LYS A 1 518 ? 55.325 38.142 30.033 1.00 31.10 ? 554 LYS A C 1 ATOM 4208 O O . LYS A 1 518 ? 56.552 38.208 30.068 1.00 30.91 ? 554 LYS A O 1 ATOM 4209 C CB . LYS A 1 518 ? 54.811 39.185 32.284 1.00 29.43 ? 554 LYS A CB 1 ATOM 4210 C CG . LYS A 1 518 ? 54.287 40.411 33.013 1.00 31.93 ? 554 LYS A CG 1 ATOM 4211 C CD . LYS A 1 518 ? 55.230 41.604 32.844 1.00 35.79 ? 554 LYS A CD 1 ATOM 4212 C CE . LYS A 1 518 ? 56.476 41.464 33.745 1.00 31.84 ? 554 LYS A CE 1 ATOM 4213 N NZ . LYS A 1 518 ? 57.456 42.568 33.473 1.00 35.37 ? 554 LYS A NZ 1 ATOM 4214 N N . ALA A 1 519 ? 54.680 37.196 29.360 1.00 29.39 ? 555 ALA A N 1 ATOM 4215 C CA . ALA A 1 519 ? 55.381 36.250 28.503 1.00 29.32 ? 555 ALA A CA 1 ATOM 4216 C C . ALA A 1 519 ? 54.937 36.508 27.069 1.00 26.85 ? 555 ALA A C 1 ATOM 4217 O O . ALA A 1 519 ? 53.805 36.219 26.714 1.00 25.44 ? 555 ALA A O 1 ATOM 4218 C CB . ALA A 1 519 ? 55.049 34.825 28.908 1.00 29.25 ? 555 ALA A CB 1 ATOM 4219 N N . ASP A 1 520 ? 55.818 37.090 26.264 1.00 27.88 ? 556 ASP A N 1 ATOM 4220 C CA . ASP A 1 520 ? 55.481 37.436 24.894 1.00 29.05 ? 556 ASP A CA 1 ATOM 4221 C C . ASP A 1 520 ? 56.719 37.339 23.992 1.00 32.74 ? 556 ASP A C 1 ATOM 4222 O O . ASP A 1 520 ? 57.806 37.001 24.462 1.00 30.35 ? 556 ASP A O 1 ATOM 4223 C CB . ASP A 1 520 ? 54.836 38.826 24.827 1.00 25.60 ? 556 ASP A CB 1 ATOM 4224 C CG . ASP A 1 520 ? 55.761 39.937 25.311 1.00 30.56 ? 556 ASP A CG 1 ATOM 4225 O OD1 . ASP A 1 520 ? 57.000 39.786 25.237 1.00 34.72 ? 556 ASP A OD1 1 ATOM 4226 O OD2 . ASP A 1 520 ? 55.246 40.974 25.765 1.00 35.15 ? 556 ASP A OD2 1 ATOM 4227 N N . THR A 1 521 ? 56.557 37.630 22.703 1.00 28.41 ? 557 THR A N 1 ATOM 4228 C CA . THR A 1 521 ? 57.668 37.489 21.770 1.00 27.82 ? 557 THR A CA 1 ATOM 4229 C C . THR A 1 521 ? 58.374 38.812 21.473 1.00 29.14 ? 557 THR A C 1 ATOM 4230 O O . THR A 1 521 ? 59.132 38.912 20.523 1.00 32.91 ? 557 THR A O 1 ATOM 4231 C CB . THR A 1 521 ? 57.201 36.843 20.474 1.00 31.17 ? 557 THR A CB 1 ATOM 4232 O OG1 . THR A 1 521 ? 56.189 37.661 19.878 1.00 31.80 ? 557 THR A OG1 1 ATOM 4233 C CG2 . THR A 1 521 ? 56.597 35.483 20.773 1.00 32.01 ? 557 THR A CG2 1 ATOM 4234 N N . VAL A 1 522 ? 58.147 39.822 22.308 1.00 29.12 ? 558 VAL A N 1 ATOM 4235 C CA . VAL A 1 522 ? 58.713 41.148 22.061 1.00 26.51 ? 558 VAL A CA 1 ATOM 4236 C C . VAL A 1 522 ? 60.208 41.225 22.413 1.00 31.64 ? 558 VAL A C 1 ATOM 4237 O O . VAL A 1 522 ? 60.658 40.678 23.420 1.00 30.93 ? 558 VAL A O 1 ATOM 4238 C CB . VAL A 1 522 ? 57.930 42.224 22.836 1.00 29.37 ? 558 VAL A CB 1 ATOM 4239 C CG1 . VAL A 1 522 ? 58.531 43.598 22.617 1.00 29.93 ? 558 VAL A CG1 1 ATOM 4240 C CG2 . VAL A 1 522 ? 56.455 42.206 22.409 1.00 27.64 ? 558 VAL A CG2 1 ATOM 4241 N N . PHE A 1 523 ? 60.976 41.888 21.559 1.00 32.06 ? 559 PHE A N 1 ATOM 4242 C CA . PHE A 1 523 ? 62.388 42.128 21.823 1.00 29.87 ? 559 PHE A CA 1 ATOM 4243 C C . PHE A 1 523 ? 62.543 43.351 22.724 1.00 29.02 ? 559 PHE A C 1 ATOM 4244 O O . PHE A 1 523 ? 62.030 44.419 22.410 1.00 27.26 ? 559 PHE A O 1 ATOM 4245 C CB . PHE A 1 523 ? 63.127 42.372 20.506 1.00 28.37 ? 559 PHE A CB 1 ATOM 4246 C CG . PHE A 1 523 ? 64.560 42.792 20.681 1.00 31.02 ? 559 PHE A CG 1 ATOM 4247 C CD1 . PHE A 1 523 ? 65.563 41.847 20.828 1.00 35.60 ? 559 PHE A CD1 1 ATOM 4248 C CD2 . PHE A 1 523 ? 64.902 44.134 20.718 1.00 32.82 ? 559 PHE A CD2 1 ATOM 4249 C CE1 . PHE A 1 523 ? 66.890 42.238 21.006 1.00 36.91 ? 559 PHE A CE1 1 ATOM 4250 C CE2 . PHE A 1 523 ? 66.221 44.529 20.893 1.00 33.61 ? 559 PHE A CE2 1 ATOM 4251 C CZ . PHE A 1 523 ? 67.212 43.584 21.043 1.00 31.72 ? 559 PHE A CZ 1 ATOM 4252 N N . ARG A 1 524 ? 63.255 43.200 23.838 1.00 29.78 ? 560 ARG A N 1 ATOM 4253 C CA . ARG A 1 524 ? 63.453 44.326 24.759 1.00 29.80 ? 560 ARG A CA 1 ATOM 4254 C C . ARG A 1 524 ? 64.913 44.452 25.186 1.00 30.79 ? 560 ARG A C 1 ATOM 4255 O O . ARG A 1 524 ? 65.623 43.450 25.314 1.00 28.02 ? 560 ARG A O 1 ATOM 4256 C CB . ARG A 1 524 ? 62.572 44.172 26.006 1.00 28.56 ? 560 ARG A CB 1 ATOM 4257 C CG . ARG A 1 524 ? 61.067 44.128 25.732 1.00 29.92 ? 560 ARG A CG 1 ATOM 4258 C CD . ARG A 1 524 ? 60.244 44.231 27.035 1.00 32.02 ? 560 ARG A CD 1 ATOM 4259 N NE . ARG A 1 524 ? 58.815 44.268 26.738 1.00 32.79 ? 560 ARG A NE 1 ATOM 4260 C CZ . ARG A 1 524 ? 58.056 43.189 26.565 1.00 34.88 ? 560 ARG A CZ 1 ATOM 4261 N NH1 . ARG A 1 524 ? 58.583 41.973 26.677 1.00 30.38 ? 560 ARG A NH1 1 ATOM 4262 N NH2 . ARG A 1 524 ? 56.766 43.322 26.267 1.00 34.42 ? 560 ARG A NH2 1 ATOM 4263 N N . LEU A 1 525 ? 65.352 45.688 25.391 1.00 26.03 ? 561 LEU A N 1 ATOM 4264 C CA . LEU A 1 525 ? 66.658 45.970 25.964 1.00 28.50 ? 561 LEU A CA 1 ATOM 4265 C C . LEU A 1 525 ? 66.396 46.701 27.261 1.00 28.00 ? 561 LEU A C 1 ATOM 4266 O O . LEU A 1 525 ? 66.117 47.893 27.246 1.00 28.52 ? 561 LEU A O 1 ATOM 4267 C CB . LEU A 1 525 ? 67.463 46.887 25.052 1.00 27.64 ? 561 LEU A CB 1 ATOM 4268 C CG . LEU A 1 525 ? 67.907 46.316 23.706 1.00 32.15 ? 561 LEU A CG 1 ATOM 4269 C CD1 . LEU A 1 525 ? 68.575 47.420 22.914 1.00 30.88 ? 561 LEU A CD1 1 ATOM 4270 C CD2 . LEU A 1 525 ? 68.849 45.119 23.913 1.00 28.20 ? 561 LEU A CD2 1 ATOM 4271 N N . ASN A 1 526 ? 66.476 45.992 28.380 1.00 28.46 ? 562 ASN A N 1 ATOM 4272 C CA . ASN A 1 526 ? 66.051 46.572 29.646 1.00 30.28 ? 562 ASN A CA 1 ATOM 4273 C C . ASN A 1 526 ? 66.933 46.122 30.812 1.00 27.57 ? 562 ASN A C 1 ATOM 4274 O O . ASN A 1 526 ? 68.007 45.556 30.613 1.00 27.42 ? 562 ASN A O 1 ATOM 4275 C CB . ASN A 1 526 ? 64.565 46.252 29.902 1.00 29.45 ? 562 ASN A CB 1 ATOM 4276 C CG . ASN A 1 526 ? 64.265 44.752 29.874 1.00 30.53 ? 562 ASN A CG 1 ATOM 4277 O OD1 . ASN A 1 526 ? 65.176 43.924 29.886 1.00 28.32 ? 562 ASN A OD1 1 ATOM 4278 N ND2 . ASN A 1 526 ? 62.978 44.400 29.848 1.00 25.26 ? 562 ASN A ND2 1 ATOM 4279 N N . TRP A 1 527 ? 66.485 46.377 32.026 1.00 28.37 ? 563 TRP A N 1 ATOM 4280 C CA . TRP A 1 527 ? 67.263 46.011 33.197 1.00 26.32 ? 563 TRP A CA 1 ATOM 4281 C C . TRP A 1 527 ? 67.535 44.509 33.194 1.00 27.76 ? 563 TRP A C 1 ATOM 4282 O O . TRP A 1 527 ? 68.632 44.057 33.550 1.00 26.23 ? 563 TRP A O 1 ATOM 4283 C CB . TRP A 1 527 ? 66.506 46.422 34.464 1.00 27.55 ? 563 TRP A CB 1 ATOM 4284 C CG . TRP A 1 527 ? 67.295 46.268 35.752 1.00 28.76 ? 563 TRP A CG 1 ATOM 4285 C CD1 . TRP A 1 527 ? 68.577 46.673 35.983 1.00 28.23 ? 563 TRP A CD1 1 ATOM 4286 C CD2 . TRP A 1 527 ? 66.821 45.707 36.992 1.00 26.18 ? 563 TRP A CD2 1 ATOM 4287 N NE1 . TRP A 1 527 ? 68.939 46.378 37.282 1.00 26.98 ? 563 TRP A NE1 1 ATOM 4288 C CE2 . TRP A 1 527 ? 67.883 45.777 37.916 1.00 23.76 ? 563 TRP A CE2 1 ATOM 4289 C CE3 . TRP A 1 527 ? 65.615 45.133 37.396 1.00 24.87 ? 563 TRP A CE3 1 ATOM 4290 C CZ2 . TRP A 1 527 ? 67.769 45.311 39.223 1.00 28.51 ? 563 TRP A CZ2 1 ATOM 4291 C CZ3 . TRP A 1 527 ? 65.502 44.660 38.692 1.00 27.13 ? 563 TRP A CZ3 1 ATOM 4292 C CH2 . TRP A 1 527 ? 66.579 44.747 39.593 1.00 28.58 ? 563 TRP A CH2 1 ATOM 4293 N N . ALA A 1 528 ? 66.540 43.728 32.790 1.00 28.21 ? 564 ALA A N 1 ATOM 4294 C CA . ALA A 1 528 ? 66.699 42.274 32.757 1.00 27.99 ? 564 ALA A CA 1 ATOM 4295 C C . ALA A 1 528 ? 67.798 41.839 31.785 1.00 28.27 ? 564 ALA A C 1 ATOM 4296 O O . ALA A 1 528 ? 68.467 40.829 32.016 1.00 29.90 ? 564 ALA A O 1 ATOM 4297 C CB . ALA A 1 528 ? 65.383 41.591 32.409 1.00 31.59 ? 564 ALA A CB 1 ATOM 4298 N N . THR A 1 529 ? 67.965 42.590 30.696 1.00 28.66 ? 565 THR A N 1 ATOM 4299 C CA . THR A 1 529 ? 69.024 42.321 29.738 1.00 26.22 ? 565 THR A CA 1 ATOM 4300 C C . THR A 1 529 ? 70.372 42.431 30.451 1.00 31.23 ? 565 THR A C 1 ATOM 4301 O O . THR A 1 529 ? 71.237 41.570 30.302 1.00 28.26 ? 565 THR A O 1 ATOM 4302 C CB . THR A 1 529 ? 69.009 43.317 28.553 1.00 31.15 ? 565 THR A CB 1 ATOM 4303 O OG1 . THR A 1 529 ? 67.692 43.400 27.991 1.00 28.48 ? 565 THR A OG1 1 ATOM 4304 C CG2 . THR A 1 529 ? 70.002 42.880 27.460 1.00 30.04 ? 565 THR A CG2 1 ATOM 4305 N N . TYR A 1 530 ? 70.552 43.496 31.226 1.00 28.45 ? 566 TYR A N 1 ATOM 4306 C CA . TYR A 1 530 ? 71.788 43.666 31.992 1.00 31.23 ? 566 TYR A CA 1 ATOM 4307 C C . TYR A 1 530 ? 71.990 42.540 33.008 1.00 31.03 ? 566 TYR A C 1 ATOM 4308 O O . TYR A 1 530 ? 73.086 41.987 33.119 1.00 30.45 ? 566 TYR A O 1 ATOM 4309 C CB . TYR A 1 530 ? 71.835 45.033 32.686 1.00 28.87 ? 566 TYR A CB 1 ATOM 4310 C CG . TYR A 1 530 ? 72.517 44.998 34.035 1.00 30.49 ? 566 TYR A CG 1 ATOM 4311 C CD1 . TYR A 1 530 ? 73.894 44.807 34.139 1.00 32.92 ? 566 TYR A CD1 1 ATOM 4312 C CD2 . TYR A 1 530 ? 71.787 45.165 35.212 1.00 32.72 ? 566 TYR A CD2 1 ATOM 4313 C CE1 . TYR A 1 530 ? 74.531 44.774 35.393 1.00 33.45 ? 566 TYR A CE1 1 ATOM 4314 C CE2 . TYR A 1 530 ? 72.406 45.134 36.462 1.00 30.68 ? 566 TYR A CE2 1 ATOM 4315 C CZ . TYR A 1 530 ? 73.773 44.939 36.547 1.00 34.64 ? 566 TYR A CZ 1 ATOM 4316 O OH . TYR A 1 530 ? 74.385 44.907 37.781 1.00 35.74 ? 566 TYR A OH 1 ATOM 4317 N N . LEU A 1 531 ? 70.939 42.190 33.741 1.00 30.69 ? 567 LEU A N 1 ATOM 4318 C CA . LEU A 1 531 ? 71.056 41.182 34.793 1.00 29.12 ? 567 LEU A CA 1 ATOM 4319 C C . LEU A 1 531 ? 71.472 39.829 34.221 1.00 34.00 ? 567 LEU A C 1 ATOM 4320 O O . LEU A 1 531 ? 72.273 39.095 34.816 1.00 30.50 ? 567 LEU A O 1 ATOM 4321 C CB . LEU A 1 531 ? 69.734 41.032 35.536 1.00 27.48 ? 567 LEU A CB 1 ATOM 4322 C CG . LEU A 1 531 ? 69.328 42.185 36.466 1.00 31.66 ? 567 LEU A CG 1 ATOM 4323 C CD1 . LEU A 1 531 ? 67.912 41.974 36.973 1.00 27.99 ? 567 LEU A CD1 1 ATOM 4324 C CD2 . LEU A 1 531 ? 70.302 42.331 37.649 1.00 32.26 ? 567 LEU A CD2 1 ATOM 4325 N N . ALA A 1 532 ? 70.909 39.485 33.072 1.00 28.30 ? 568 ALA A N 1 ATOM 4326 C CA . ALA A 1 532 ? 71.237 38.210 32.448 1.00 28.59 ? 568 ALA A CA 1 ATOM 4327 C C . ALA A 1 532 ? 72.622 38.277 31.786 1.00 32.55 ? 568 ALA A C 1 ATOM 4328 O O . ALA A 1 532 ? 73.463 37.410 32.005 1.00 33.71 ? 568 ALA A O 1 ATOM 4329 C CB . ALA A 1 532 ? 70.177 37.836 31.428 1.00 29.72 ? 568 ALA A CB 1 ATOM 4330 N N . SER A 1 533 ? 72.861 39.315 30.993 1.00 30.14 ? 569 SER A N 1 ATOM 4331 C CA . SER A 1 533 ? 74.112 39.413 30.237 1.00 32.55 ? 569 SER A CA 1 ATOM 4332 C C . SER A 1 533 ? 75.372 39.595 31.097 1.00 38.15 ? 569 SER A C 1 ATOM 4333 O O . SER A 1 533 ? 76.407 38.989 30.819 1.00 38.12 ? 569 SER A O 1 ATOM 4334 C CB . SER A 1 533 ? 74.030 40.548 29.222 1.00 30.99 ? 569 SER A CB 1 ATOM 4335 O OG . SER A 1 533 ? 75.286 40.731 28.593 1.00 34.63 ? 569 SER A OG 1 ATOM 4336 N N . THR A 1 534 ? 75.279 40.432 32.131 1.00 34.39 ? 570 THR A N 1 ATOM 4337 C CA . THR A 1 534 ? 76.434 40.805 32.951 1.00 32.58 ? 570 THR A CA 1 ATOM 4338 C C . THR A 1 534 ? 76.536 40.042 34.268 1.00 36.32 ? 570 THR A C 1 ATOM 4339 O O . THR A 1 534 ? 77.612 39.578 34.646 1.00 35.86 ? 570 THR A O 1 ATOM 4340 C CB . THR A 1 534 ? 76.415 42.301 33.287 1.00 32.90 ? 570 THR A CB 1 ATOM 4341 O OG1 . THR A 1 534 ? 76.627 43.065 32.092 1.00 33.24 ? 570 THR A OG1 1 ATOM 4342 C CG2 . THR A 1 534 ? 77.502 42.637 34.321 1.00 35.02 ? 570 THR A CG2 1 ATOM 4343 N N . GLU A 1 535 ? 75.415 39.918 34.967 1.00 33.68 ? 571 GLU A N 1 ATOM 4344 C CA . GLU A 1 535 ? 75.404 39.287 36.276 1.00 31.19 ? 571 GLU A CA 1 ATOM 4345 C C . GLU A 1 535 ? 75.039 37.803 36.218 1.00 34.96 ? 571 GLU A C 1 ATOM 4346 O O . GLU A 1 535 ? 75.065 37.114 37.237 1.00 34.53 ? 571 GLU A O 1 ATOM 4347 C CB . GLU A 1 535 ? 74.457 40.053 37.216 1.00 34.81 ? 571 GLU A CB 1 ATOM 4348 C CG . GLU A 1 535 ? 74.835 41.524 37.389 1.00 34.22 ? 571 GLU A CG 1 ATOM 4349 C CD . GLU A 1 535 ? 76.207 41.703 38.049 1.00 41.50 ? 571 GLU A CD 1 ATOM 4350 O OE1 . GLU A 1 535 ? 76.687 40.754 38.712 1.00 44.22 ? 571 GLU A OE1 1 ATOM 4351 O OE2 . GLU A 1 535 ? 76.803 42.793 37.906 1.00 42.14 ? 571 GLU A OE2 1 ATOM 4352 N N . ASN A 1 536 ? 74.706 37.307 35.024 1.00 31.57 ? 572 ASN A N 1 ATOM 4353 C CA . ASN A 1 536 ? 74.386 35.891 34.846 1.00 31.04 ? 572 ASN A CA 1 ATOM 4354 C C . ASN A 1 536 ? 73.192 35.436 35.664 1.00 29.98 ? 572 ASN A C 1 ATOM 4355 O O . ASN A 1 536 ? 73.180 34.337 36.220 1.00 31.47 ? 572 ASN A O 1 ATOM 4356 C CB . ASN A 1 536 ? 75.602 35.011 35.148 1.00 34.51 ? 572 ASN A CB 1 ATOM 4357 C CG . ASN A 1 536 ? 76.699 35.192 34.127 1.00 43.63 ? 572 ASN A CG 1 ATOM 4358 O OD1 . ASN A 1 536 ? 76.456 35.147 32.912 1.00 36.20 ? 572 ASN A OD1 1 ATOM 4359 N ND2 . ASN A 1 536 ? 77.911 35.429 34.606 1.00 43.60 ? 572 ASN A ND2 1 ATOM 4360 N N . ILE A 1 537 ? 72.182 36.294 35.726 1.00 27.89 ? 573 ILE A N 1 ATOM 4361 C CA . ILE A 1 537 ? 70.943 35.971 36.403 1.00 27.29 ? 573 ILE A CA 1 ATOM 4362 C C . ILE A 1 537 ? 69.885 35.635 35.370 1.00 27.55 ? 573 ILE A C 1 ATOM 4363 O O . ILE A 1 537 ? 69.751 36.319 34.373 1.00 32.03 ? 573 ILE A O 1 ATOM 4364 C CB . ILE A 1 537 ? 70.453 37.164 37.247 1.00 28.64 ? 573 ILE A CB 1 ATOM 4365 C CG1 . ILE A 1 537 ? 71.472 37.498 38.336 1.00 27.24 ? 573 ILE A CG1 1 ATOM 4366 C CG2 . ILE A 1 537 ? 69.114 36.854 37.861 1.00 29.05 ? 573 ILE A CG2 1 ATOM 4367 C CD1 . ILE A 1 537 ? 71.343 38.920 38.891 1.00 30.09 ? 573 ILE A CD1 1 ATOM 4368 N N . ILE A 1 538 ? 69.138 34.569 35.602 1.00 33.18 ? 574 ILE A N 1 ATOM 4369 C CA . ILE A 1 538 ? 67.983 34.265 34.773 1.00 32.24 ? 574 ILE A CA 1 ATOM 4370 C C . ILE A 1 538 ? 66.831 35.154 35.242 1.00 32.55 ? 574 ILE A C 1 ATOM 4371 O O . ILE A 1 538 ? 66.540 35.199 36.435 1.00 30.83 ? 574 ILE A O 1 ATOM 4372 C CB . ILE A 1 538 ? 67.582 32.790 34.938 1.00 30.25 ? 574 ILE A CB 1 ATOM 4373 C CG1 . ILE A 1 538 ? 68.703 31.874 34.428 1.00 29.72 ? 574 ILE A CG1 1 ATOM 4374 C CG2 . ILE A 1 538 ? 66.261 32.514 34.233 1.00 30.98 ? 574 ILE A CG2 1 ATOM 4375 C CD1 . ILE A 1 538 ? 68.389 30.396 34.552 1.00 36.48 ? 574 ILE A CD1 1 ATOM 4376 N N . VAL A 1 539 ? 66.193 35.882 34.329 1.00 30.00 ? 575 VAL A N 1 ATOM 4377 C CA . VAL A 1 539 ? 65.014 36.660 34.717 1.00 29.50 ? 575 VAL A CA 1 ATOM 4378 C C . VAL A 1 539 ? 63.762 36.050 34.086 1.00 30.23 ? 575 VAL A C 1 ATOM 4379 O O . VAL A 1 539 ? 63.607 36.023 32.860 1.00 31.21 ? 575 VAL A O 1 ATOM 4380 C CB . VAL A 1 539 ? 65.129 38.145 34.327 1.00 29.76 ? 575 VAL A CB 1 ATOM 4381 C CG1 . VAL A 1 539 ? 64.048 38.964 35.035 1.00 31.48 ? 575 VAL A CG1 1 ATOM 4382 C CG2 . VAL A 1 539 ? 66.496 38.682 34.674 1.00 27.49 ? 575 VAL A CG2 1 ATOM 4383 N N . ALA A 1 540 ? 62.881 35.539 34.932 1.00 28.96 ? 576 ALA A N 1 ATOM 4384 C CA . ALA A 1 540 ? 61.698 34.829 34.476 1.00 27.32 ? 576 ALA A CA 1 ATOM 4385 C C . ALA A 1 540 ? 60.424 35.619 34.756 1.00 31.37 ? 576 ALA A C 1 ATOM 4386 O O . ALA A 1 540 ? 60.347 36.365 35.744 1.00 25.86 ? 576 ALA A O 1 ATOM 4387 C CB . ALA A 1 540 ? 61.630 33.459 35.138 1.00 30.91 ? 576 ALA A CB 1 ATOM 4388 N N . SER A 1 541 ? 59.438 35.468 33.867 1.00 29.62 ? 577 SER A N 1 ATOM 4389 C CA . SER A 1 541 ? 58.086 35.965 34.099 1.00 28.31 ? 577 SER A CA 1 ATOM 4390 C C . SER A 1 541 ? 57.074 34.871 33.772 1.00 29.92 ? 577 SER A C 1 ATOM 4391 O O . SER A 1 541 ? 57.324 34.015 32.917 1.00 29.04 ? 577 SER A O 1 ATOM 4392 C CB . SER A 1 541 ? 57.807 37.199 33.247 1.00 29.22 ? 577 SER A CB 1 ATOM 4393 O OG . SER A 1 541 ? 58.768 38.204 33.493 1.00 33.49 ? 577 SER A OG 1 ATOM 4394 N N . PHE A 1 542 ? 55.929 34.909 34.441 1.00 26.44 ? 578 PHE A N 1 ATOM 4395 C CA . PHE A 1 542 ? 54.942 33.852 34.335 1.00 28.45 ? 578 PHE A CA 1 ATOM 4396 C C . PHE A 1 542 ? 53.572 34.475 34.250 1.00 29.61 ? 578 PHE A C 1 ATOM 4397 O O . PHE A 1 542 ? 53.256 35.407 35.002 1.00 27.85 ? 578 PHE A O 1 ATOM 4398 C CB . PHE A 1 542 ? 55.031 32.932 35.551 1.00 26.82 ? 578 PHE A CB 1 ATOM 4399 C CG . PHE A 1 542 ? 54.006 31.830 35.577 1.00 28.96 ? 578 PHE A CG 1 ATOM 4400 C CD1 . PHE A 1 542 ? 54.165 30.691 34.803 1.00 32.05 ? 578 PHE A CD1 1 ATOM 4401 C CD2 . PHE A 1 542 ? 52.911 31.907 36.421 1.00 28.67 ? 578 PHE A CD2 1 ATOM 4402 C CE1 . PHE A 1 542 ? 53.238 29.660 34.857 1.00 30.75 ? 578 PHE A CE1 1 ATOM 4403 C CE2 . PHE A 1 542 ? 51.983 30.890 36.478 1.00 28.37 ? 578 PHE A CE2 1 ATOM 4404 C CZ . PHE A 1 542 ? 52.142 29.767 35.692 1.00 31.91 ? 578 PHE A CZ 1 ATOM 4405 N N . ASP A 1 543 ? 52.759 33.964 33.330 1.00 25.71 ? 579 ASP A N 1 ATOM 4406 C CA . ASP A 1 543 ? 51.393 34.446 33.170 1.00 29.12 ? 579 ASP A CA 1 ATOM 4407 C C . ASP A 1 543 ? 50.428 33.418 33.727 1.00 32.55 ? 579 ASP A C 1 ATOM 4408 O O . ASP A 1 543 ? 50.161 32.405 33.080 1.00 33.23 ? 579 ASP A O 1 ATOM 4409 C CB . ASP A 1 543 ? 51.065 34.702 31.693 1.00 26.25 ? 579 ASP A CB 1 ATOM 4410 C CG . ASP A 1 543 ? 51.695 35.979 31.167 1.00 32.02 ? 579 ASP A CG 1 ATOM 4411 O OD1 . ASP A 1 543 ? 51.912 36.927 31.976 1.00 31.73 ? 579 ASP A OD1 1 ATOM 4412 O OD2 . ASP A 1 543 ? 51.981 36.035 29.944 1.00 29.64 ? 579 ASP A OD2 1 ATOM 4413 N N . GLY A 1 544 ? 49.893 33.688 34.914 1.00 30.10 ? 580 GLY A N 1 ATOM 4414 C CA . GLY A 1 544 ? 49.046 32.732 35.610 1.00 32.70 ? 580 GLY A CA 1 ATOM 4415 C C . GLY A 1 544 ? 47.585 33.127 35.595 1.00 32.05 ? 580 GLY A C 1 ATOM 4416 O O . GLY A 1 544 ? 47.156 33.875 34.720 1.00 29.28 ? 580 GLY A O 1 ATOM 4417 N N . ARG A 1 545 ? 46.809 32.638 36.559 1.00 29.85 ? 581 ARG A N 1 ATOM 4418 C CA . ARG A 1 545 ? 45.398 32.996 36.564 1.00 31.96 ? 581 ARG A CA 1 ATOM 4419 C C . ARG A 1 545 ? 45.243 34.511 36.672 1.00 27.31 ? 581 ARG A C 1 ATOM 4420 O O . ARG A 1 545 ? 46.046 35.191 37.314 1.00 30.20 ? 581 ARG A O 1 ATOM 4421 C CB . ARG A 1 545 ? 44.617 32.228 37.639 1.00 31.76 ? 581 ARG A CB 1 ATOM 4422 C CG . ARG A 1 545 ? 44.200 30.828 37.165 1.00 31.50 ? 581 ARG A CG 1 ATOM 4423 C CD . ARG A 1 545 ? 43.649 29.967 38.294 1.00 36.99 ? 581 ARG A CD 1 ATOM 4424 N NE . ARG A 1 545 ? 44.666 29.705 39.312 1.00 35.86 ? 581 ARG A NE 1 ATOM 4425 C CZ . ARG A 1 545 ? 44.464 28.991 40.419 1.00 41.53 ? 581 ARG A CZ 1 ATOM 4426 N NH1 . ARG A 1 545 ? 43.271 28.463 40.673 1.00 38.46 ? 581 ARG A NH1 1 ATOM 4427 N NH2 . ARG A 1 545 ? 45.460 28.813 41.281 1.00 43.05 ? 581 ARG A NH2 1 ATOM 4428 N N . GLY A 1 546 ? 44.231 35.042 36.001 1.00 26.49 ? 582 GLY A N 1 ATOM 4429 C CA . GLY A 1 546 ? 44.083 36.472 35.872 1.00 26.04 ? 582 GLY A CA 1 ATOM 4430 C C . GLY A 1 546 ? 44.728 37.052 34.628 1.00 26.18 ? 582 GLY A C 1 ATOM 4431 O O . GLY A 1 546 ? 44.340 38.140 34.189 1.00 28.44 ? 582 GLY A O 1 ATOM 4432 N N . SER A 1 547 ? 45.702 36.350 34.045 1.00 26.50 ? 583 SER A N 1 ATOM 4433 C CA . SER A 1 547 ? 46.368 36.864 32.836 1.00 27.29 ? 583 SER A CA 1 ATOM 4434 C C . SER A 1 547 ? 45.432 36.918 31.611 1.00 27.83 ? 583 SER A C 1 ATOM 4435 O O . SER A 1 547 ? 44.333 36.376 31.634 1.00 29.74 ? 583 SER A O 1 ATOM 4436 C CB . SER A 1 547 ? 47.664 36.104 32.530 1.00 30.07 ? 583 SER A CB 1 ATOM 4437 O OG . SER A 1 547 ? 47.424 34.739 32.234 1.00 30.25 ? 583 SER A OG 1 ATOM 4438 N N . GLY A 1 548 ? 45.861 37.598 30.557 1.00 26.37 ? 584 GLY A N 1 ATOM 4439 C CA . GLY A 1 548 ? 44.959 37.932 29.470 1.00 27.78 ? 584 GLY A CA 1 ATOM 4440 C C . GLY A 1 548 ? 45.200 37.163 28.183 1.00 28.23 ? 584 GLY A C 1 ATOM 4441 O O . GLY A 1 548 ? 46.129 36.353 28.075 1.00 23.72 ? 584 GLY A O 1 ATOM 4442 N N . TYR A 1 549 ? 44.321 37.401 27.216 1.00 31.32 ? 585 TYR A N 1 ATOM 4443 C CA . TYR A 1 549 ? 44.528 36.946 25.833 1.00 29.02 ? 585 TYR A CA 1 ATOM 4444 C C . TYR A 1 549 ? 44.443 35.436 25.699 1.00 28.94 ? 585 TYR A C 1 ATOM 4445 O O . TYR A 1 549 ? 44.845 34.875 24.675 1.00 32.00 ? 585 TYR A O 1 ATOM 4446 C CB . TYR A 1 549 ? 45.855 37.496 25.295 1.00 25.42 ? 585 TYR A CB 1 ATOM 4447 C CG . TYR A 1 549 ? 45.967 38.976 25.571 1.00 27.19 ? 585 TYR A CG 1 ATOM 4448 C CD1 . TYR A 1 549 ? 45.170 39.878 24.891 1.00 28.35 ? 585 TYR A CD1 1 ATOM 4449 C CD2 . TYR A 1 549 ? 46.832 39.465 26.540 1.00 26.73 ? 585 TYR A CD2 1 ATOM 4450 C CE1 . TYR A 1 549 ? 45.240 41.224 25.146 1.00 28.92 ? 585 TYR A CE1 1 ATOM 4451 C CE2 . TYR A 1 549 ? 46.915 40.819 26.802 1.00 27.28 ? 585 TYR A CE2 1 ATOM 4452 C CZ . TYR A 1 549 ? 46.110 41.691 26.100 1.00 28.75 ? 585 TYR A CZ 1 ATOM 4453 O OH . TYR A 1 549 ? 46.165 43.040 26.335 1.00 32.52 ? 585 TYR A OH 1 ATOM 4454 N N . GLN A 1 550 ? 43.884 34.794 26.726 1.00 27.70 ? 586 GLN A N 1 ATOM 4455 C CA . GLN A 1 550 ? 43.718 33.349 26.749 1.00 29.08 ? 586 GLN A CA 1 ATOM 4456 C C . GLN A 1 550 ? 42.294 32.891 27.077 1.00 29.98 ? 586 GLN A C 1 ATOM 4457 O O . GLN A 1 550 ? 42.083 31.724 27.392 1.00 33.75 ? 586 GLN A O 1 ATOM 4458 C CB . GLN A 1 550 ? 44.687 32.743 27.763 1.00 33.29 ? 586 GLN A CB 1 ATOM 4459 C CG . GLN A 1 550 ? 46.140 33.056 27.479 1.00 29.27 ? 586 GLN A CG 1 ATOM 4460 C CD . GLN A 1 550 ? 46.976 33.025 28.740 1.00 33.09 ? 586 GLN A CD 1 ATOM 4461 O OE1 . GLN A 1 550 ? 47.230 34.065 29.359 1.00 35.64 ? 586 GLN A OE1 1 ATOM 4462 N NE2 . GLN A 1 550 ? 47.399 31.840 29.135 1.00 25.42 ? 586 GLN A NE2 1 ATOM 4463 N N . GLY A 1 551 ? 41.322 33.797 27.018 1.00 28.82 ? 587 GLY A N 1 ATOM 4464 C CA . GLY A 1 551 ? 39.946 33.435 27.317 1.00 29.85 ? 587 GLY A CA 1 ATOM 4465 C C . GLY A 1 551 ? 39.527 33.786 28.732 1.00 31.55 ? 587 GLY A C 1 ATOM 4466 O O . GLY A 1 551 ? 40.369 34.038 29.581 1.00 34.45 ? 587 GLY A O 1 ATOM 4467 N N . ASP A 1 552 ? 38.227 33.811 28.993 1.00 28.98 ? 588 ASP A N 1 ATOM 4468 C CA . ASP A 1 552 ? 37.720 34.275 30.287 1.00 32.68 ? 588 ASP A CA 1 ATOM 4469 C C . ASP A 1 552 ? 37.935 33.303 31.454 1.00 33.39 ? 588 ASP A C 1 ATOM 4470 O O . ASP A 1 552 ? 37.987 33.720 32.609 1.00 31.83 ? 588 ASP A O 1 ATOM 4471 C CB . ASP A 1 552 ? 36.234 34.637 30.192 1.00 30.87 ? 588 ASP A CB 1 ATOM 4472 C CG . ASP A 1 552 ? 35.991 35.914 29.401 1.00 37.63 ? 588 ASP A CG 1 ATOM 4473 O OD1 . ASP A 1 552 ? 36.992 36.590 29.045 1.00 33.87 ? 588 ASP A OD1 1 ATOM 4474 O OD2 . ASP A 1 552 ? 34.803 36.245 29.153 1.00 38.41 ? 588 ASP A OD2 1 ATOM 4475 N N . LYS A 1 553 ? 38.037 32.011 31.163 1.00 31.03 ? 589 LYS A N 1 ATOM 4476 C CA . LYS A 1 553 ? 38.220 31.030 32.231 1.00 34.21 ? 589 LYS A CA 1 ATOM 4477 C C . LYS A 1 553 ? 39.463 31.414 33.023 1.00 31.38 ? 589 LYS A C 1 ATOM 4478 O O . LYS A 1 553 ? 39.480 31.366 34.242 1.00 30.34 ? 589 LYS A O 1 ATOM 4479 C CB . LYS A 1 553 ? 38.359 29.622 31.653 1.00 34.19 ? 589 LYS A CB 1 ATOM 4480 C CG . LYS A 1 553 ? 38.852 28.565 32.655 1.00 40.57 ? 589 LYS A CG 1 ATOM 4481 C CD . LYS A 1 553 ? 37.765 28.151 33.629 1.00 41.20 ? 589 LYS A CD 1 ATOM 4482 N N . ILE A 1 554 ? 40.488 31.839 32.300 1.00 32.64 ? 590 ILE A N 1 ATOM 4483 C CA . ILE A 1 554 ? 41.736 32.259 32.899 1.00 32.57 ? 590 ILE A CA 1 ATOM 4484 C C . ILE A 1 554 ? 41.647 33.704 33.392 1.00 29.81 ? 590 ILE A C 1 ATOM 4485 O O . ILE A 1 554 ? 41.963 33.978 34.540 1.00 27.57 ? 590 ILE A O 1 ATOM 4486 C CB . ILE A 1 554 ? 42.904 32.036 31.914 1.00 31.11 ? 590 ILE A CB 1 ATOM 4487 C CG1 . ILE A 1 554 ? 43.233 30.541 31.856 1.00 33.63 ? 590 ILE A CG1 1 ATOM 4488 C CG2 . ILE A 1 554 ? 44.131 32.816 32.322 1.00 29.36 ? 590 ILE A CG2 1 ATOM 4489 C CD1 . ILE A 1 554 ? 44.157 30.156 30.739 1.00 32.85 ? 590 ILE A CD1 1 ATOM 4490 N N . MET A 1 555 ? 41.182 34.621 32.550 1.00 29.24 ? 591 MET A N 1 ATOM 4491 C CA . MET A 1 555 ? 41.163 36.027 32.942 1.00 29.37 ? 591 MET A CA 1 ATOM 4492 C C . MET A 1 555 ? 40.250 36.329 34.140 1.00 30.62 ? 591 MET A C 1 ATOM 4493 O O . MET A 1 555 ? 40.620 37.107 35.019 1.00 29.86 ? 591 MET A O 1 ATOM 4494 C CB . MET A 1 555 ? 40.814 36.938 31.769 1.00 28.92 ? 591 MET A CB 1 ATOM 4495 C CG . MET A 1 555 ? 41.189 38.376 32.045 1.00 27.47 ? 591 MET A CG 1 ATOM 4496 S SD . MET A 1 555 ? 40.845 39.500 30.676 1.00 34.02 ? 591 MET A SD 1 ATOM 4497 C CE . MET A 1 555 ? 39.064 39.589 30.693 1.00 31.48 ? 591 MET A CE 1 ATOM 4498 N N . HIS A 1 556 ? 39.081 35.698 34.187 1.00 28.88 ? 592 HIS A N 1 ATOM 4499 C CA . HIS A 1 556 ? 38.087 35.992 35.223 1.00 27.09 ? 592 HIS A CA 1 ATOM 4500 C C . HIS A 1 556 ? 38.285 35.177 36.504 1.00 30.71 ? 592 HIS A C 1 ATOM 4501 O O . HIS A 1 556 ? 37.558 35.359 37.480 1.00 35.65 ? 592 HIS A O 1 ATOM 4502 C CB . HIS A 1 556 ? 36.673 35.764 34.682 1.00 27.57 ? 592 HIS A CB 1 ATOM 4503 C CG . HIS A 1 556 ? 36.198 36.827 33.741 1.00 31.54 ? 592 HIS A CG 1 ATOM 4504 N ND1 . HIS A 1 556 ? 36.808 38.061 33.633 1.00 32.03 ? 592 HIS A ND1 1 ATOM 4505 C CD2 . HIS A 1 556 ? 35.161 36.849 32.873 1.00 33.75 ? 592 HIS A CD2 1 ATOM 4506 C CE1 . HIS A 1 556 ? 36.169 38.792 32.741 1.00 29.95 ? 592 HIS A CE1 1 ATOM 4507 N NE2 . HIS A 1 556 ? 35.167 38.076 32.260 1.00 37.70 ? 592 HIS A NE2 1 ATOM 4508 N N . ALA A 1 557 ? 39.272 34.288 36.514 1.00 31.58 ? 593 ALA A N 1 ATOM 4509 C CA . ALA A 1 557 ? 39.532 33.461 37.690 1.00 29.40 ? 593 ALA A CA 1 ATOM 4510 C C . ALA A 1 557 ? 39.727 34.335 38.919 1.00 31.97 ? 593 ALA A C 1 ATOM 4511 O O . ALA A 1 557 ? 39.521 33.906 40.053 1.00 34.30 ? 593 ALA A O 1 ATOM 4512 C CB . ALA A 1 557 ? 40.754 32.622 37.460 1.00 34.10 ? 593 ALA A CB 1 ATOM 4513 N N . ILE A 1 558 ? 40.105 35.580 38.671 1.00 32.70 ? 594 ILE A N 1 ATOM 4514 C CA . ILE A 1 558 ? 40.509 36.519 39.714 1.00 33.85 ? 594 ILE A CA 1 ATOM 4515 C C . ILE A 1 558 ? 39.388 37.475 40.122 1.00 31.81 ? 594 ILE A C 1 ATOM 4516 O O . ILE A 1 558 ? 39.581 38.360 40.964 1.00 30.59 ? 594 ILE A O 1 ATOM 4517 C CB . ILE A 1 558 ? 41.730 37.320 39.208 1.00 35.01 ? 594 ILE A CB 1 ATOM 4518 C CG1 . ILE A 1 558 ? 42.841 37.240 40.231 1.00 38.29 ? 594 ILE A CG1 1 ATOM 4519 C CG2 . ILE A 1 558 ? 41.349 38.723 38.754 1.00 31.25 ? 594 ILE A CG2 1 ATOM 4520 C CD1 . ILE A 1 558 ? 43.235 35.816 40.485 1.00 33.91 ? 594 ILE A CD1 1 ATOM 4521 N N . ASN A 1 559 ? 38.215 37.301 39.517 1.00 31.27 ? 595 ASN A N 1 ATOM 4522 C CA . ASN A 1 559 ? 37.065 38.171 39.774 1.00 31.36 ? 595 ASN A CA 1 ATOM 4523 C C . ASN A 1 559 ? 36.743 38.301 41.266 1.00 34.64 ? 595 ASN A C 1 ATOM 4524 O O . ASN A 1 559 ? 36.642 37.296 41.963 1.00 32.65 ? 595 ASN A O 1 ATOM 4525 C CB . ASN A 1 559 ? 35.847 37.637 39.033 1.00 29.65 ? 595 ASN A CB 1 ATOM 4526 C CG . ASN A 1 559 ? 34.689 38.575 39.096 1.00 32.28 ? 595 ASN A CG 1 ATOM 4527 O OD1 . ASN A 1 559 ? 34.835 39.775 38.868 1.00 32.50 ? 595 ASN A OD1 1 ATOM 4528 N ND2 . ASN A 1 559 ? 33.523 38.045 39.434 1.00 37.09 ? 595 ASN A ND2 1 ATOM 4529 N N . ARG A 1 560 ? 36.598 39.536 41.750 1.00 32.48 ? 596 ARG A N 1 ATOM 4530 C CA . ARG A 1 560 ? 36.286 39.813 43.160 1.00 34.06 ? 596 ARG A CA 1 ATOM 4531 C C . ARG A 1 560 ? 37.296 39.226 44.146 1.00 35.31 ? 596 ARG A C 1 ATOM 4532 O O . ARG A 1 560 ? 37.039 39.205 45.349 1.00 32.83 ? 596 ARG A O 1 ATOM 4533 C CB . ARG A 1 560 ? 34.879 39.321 43.531 1.00 34.07 ? 596 ARG A CB 1 ATOM 4534 C CG . ARG A 1 560 ? 33.755 39.986 42.729 1.00 35.06 ? 596 ARG A CG 1 ATOM 4535 C CD . ARG A 1 560 ? 32.397 39.363 43.040 1.00 44.46 ? 596 ARG A CD 1 ATOM 4536 N NE . ARG A 1 560 ? 31.668 40.113 44.062 1.00 42.83 ? 596 ARG A NE 1 ATOM 4537 C CZ . ARG A 1 560 ? 31.524 39.715 45.319 1.00 47.43 ? 596 ARG A CZ 1 ATOM 4538 N NH1 . ARG A 1 560 ? 32.054 38.564 45.734 1.00 55.18 ? 596 ARG A NH1 1 ATOM 4539 N NH2 . ARG A 1 560 ? 30.841 40.468 46.166 1.00 47.41 ? 596 ARG A NH2 1 ATOM 4540 N N . ARG A 1 561 ? 38.434 38.759 43.640 1.00 30.31 ? 597 ARG A N 1 ATOM 4541 C CA . ARG A 1 561 ? 39.419 38.072 44.478 1.00 35.38 ? 597 ARG A CA 1 ATOM 4542 C C . ARG A 1 561 ? 40.870 38.443 44.166 1.00 31.39 ? 597 ARG A C 1 ATOM 4543 O O . ARG A 1 561 ? 41.725 37.561 44.063 1.00 31.36 ? 597 ARG A O 1 ATOM 4544 C CB . ARG A 1 561 ? 39.248 36.554 44.350 1.00 35.64 ? 597 ARG A CB 1 ATOM 4545 C CG . ARG A 1 561 ? 37.974 36.040 44.989 1.00 39.95 ? 597 ARG A CG 1 ATOM 4546 C CD . ARG A 1 561 ? 37.957 36.442 46.453 1.00 43.57 ? 597 ARG A CD 1 ATOM 4547 N NE . ARG A 1 561 ? 36.912 35.781 47.229 1.00 50.64 ? 597 ARG A NE 1 ATOM 4548 C CZ . ARG A 1 561 ? 35.720 36.307 47.487 1.00 49.98 ? 597 ARG A CZ 1 ATOM 4549 N NH1 . ARG A 1 561 ? 35.405 37.513 47.024 1.00 40.18 ? 597 ARG A NH1 1 ATOM 4550 N NH2 . ARG A 1 561 ? 34.842 35.620 48.207 1.00 55.72 ? 597 ARG A NH2 1 ATOM 4551 N N . LEU A 1 562 ? 41.156 39.734 44.013 1.00 31.30 ? 598 LEU A N 1 ATOM 4552 C CA . LEU A 1 562 ? 42.544 40.170 43.801 1.00 29.56 ? 598 LEU A CA 1 ATOM 4553 C C . LEU A 1 562 ? 43.423 39.741 44.986 1.00 33.07 ? 598 LEU A C 1 ATOM 4554 O O . LEU A 1 562 ? 42.959 39.703 46.125 1.00 30.76 ? 598 LEU A O 1 ATOM 4555 C CB . LEU A 1 562 ? 42.624 41.683 43.616 1.00 28.06 ? 598 LEU A CB 1 ATOM 4556 C CG . LEU A 1 562 ? 41.859 42.304 42.449 1.00 27.95 ? 598 LEU A CG 1 ATOM 4557 C CD1 . LEU A 1 562 ? 42.233 43.776 42.346 1.00 26.95 ? 598 LEU A CD1 1 ATOM 4558 C CD2 . LEU A 1 562 ? 42.177 41.575 41.149 1.00 26.86 ? 598 LEU A CD2 1 ATOM 4559 N N . GLY A 1 563 ? 44.685 39.420 44.713 1.00 28.90 ? 599 GLY A N 1 ATOM 4560 C CA . GLY A 1 563 ? 45.606 39.008 45.750 1.00 27.48 ? 599 GLY A CA 1 ATOM 4561 C C . GLY A 1 563 ? 45.455 37.550 46.157 1.00 31.09 ? 599 GLY A C 1 ATOM 4562 O O . GLY A 1 563 ? 45.883 37.157 47.239 1.00 31.97 ? 599 GLY A O 1 ATOM 4563 N N . THR A 1 564 ? 44.849 36.740 45.297 1.00 32.25 ? 600 THR A N 1 ATOM 4564 C CA . THR A 1 564 ? 44.710 35.318 45.586 1.00 29.24 ? 600 THR A CA 1 ATOM 4565 C C . THR A 1 564 ? 45.409 34.440 44.540 1.00 33.27 ? 600 THR A C 1 ATOM 4566 O O . THR A 1 564 ? 46.600 34.169 44.666 1.00 32.64 ? 600 THR A O 1 ATOM 4567 C CB . THR A 1 564 ? 43.228 34.914 45.775 1.00 31.00 ? 600 THR A CB 1 ATOM 4568 O OG1 . THR A 1 564 ? 42.491 35.152 44.568 1.00 34.62 ? 600 THR A OG1 1 ATOM 4569 C CG2 . THR A 1 564 ? 42.603 35.721 46.907 1.00 34.64 ? 600 THR A CG2 1 ATOM 4570 N N . PHE A 1 565 ? 44.683 34.010 43.509 1.00 31.96 ? 601 PHE A N 1 ATOM 4571 C CA . PHE A 1 565 ? 45.223 33.071 42.529 1.00 33.44 ? 601 PHE A CA 1 ATOM 4572 C C . PHE A 1 565 ? 46.453 33.593 41.795 1.00 31.52 ? 601 PHE A C 1 ATOM 4573 O O . PHE A 1 565 ? 47.376 32.829 41.501 1.00 31.25 ? 601 PHE A O 1 ATOM 4574 C CB . PHE A 1 565 ? 44.151 32.667 41.502 1.00 33.63 ? 601 PHE A CB 1 ATOM 4575 C CG . PHE A 1 565 ? 42.987 31.942 42.105 1.00 35.35 ? 601 PHE A CG 1 ATOM 4576 C CD1 . PHE A 1 565 ? 43.189 30.943 43.043 1.00 37.64 ? 601 PHE A CD1 1 ATOM 4577 C CD2 . PHE A 1 565 ? 41.693 32.273 41.754 1.00 36.48 ? 601 PHE A CD2 1 ATOM 4578 C CE1 . PHE A 1 565 ? 42.122 30.279 43.615 1.00 37.26 ? 601 PHE A CE1 1 ATOM 4579 C CE2 . PHE A 1 565 ? 40.616 31.612 42.323 1.00 41.96 ? 601 PHE A CE2 1 ATOM 4580 C CZ . PHE A 1 565 ? 40.832 30.614 43.253 1.00 37.72 ? 601 PHE A CZ 1 ATOM 4581 N N . GLU A 1 566 ? 46.462 34.882 41.463 1.00 30.00 ? 602 GLU A N 1 ATOM 4582 C CA . GLU A 1 566 ? 47.602 35.427 40.741 1.00 28.43 ? 602 GLU A CA 1 ATOM 4583 C C . GLU A 1 566 ? 48.868 35.403 41.604 1.00 31.06 ? 602 GLU A C 1 ATOM 4584 O O . GLU A 1 566 ? 49.968 35.224 41.088 1.00 32.11 ? 602 GLU A O 1 ATOM 4585 C CB . GLU A 1 566 ? 47.310 36.823 40.160 1.00 27.94 ? 602 GLU A CB 1 ATOM 4586 C CG . GLU A 1 566 ? 47.521 37.964 41.130 1.00 30.39 ? 602 GLU A CG 1 ATOM 4587 C CD . GLU A 1 566 ? 46.323 38.191 42.045 1.00 32.97 ? 602 GLU A CD 1 ATOM 4588 O OE1 . GLU A 1 566 ? 45.674 37.193 42.465 1.00 34.67 ? 602 GLU A OE1 1 ATOM 4589 O OE2 . GLU A 1 566 ? 46.033 39.375 42.348 1.00 31.44 ? 602 GLU A OE2 1 ATOM 4590 N N . VAL A 1 567 ? 48.706 35.526 42.921 1.00 30.09 ? 603 VAL A N 1 ATOM 4591 C CA . VAL A 1 567 ? 49.832 35.439 43.852 1.00 28.26 ? 603 VAL A CA 1 ATOM 4592 C C . VAL A 1 567 ? 50.295 33.986 44.027 1.00 31.75 ? 603 VAL A C 1 ATOM 4593 O O . VAL A 1 567 ? 51.479 33.671 43.842 1.00 28.43 ? 603 VAL A O 1 ATOM 4594 C CB . VAL A 1 567 ? 49.479 36.064 45.219 1.00 28.04 ? 603 VAL A CB 1 ATOM 4595 C CG1 . VAL A 1 567 ? 50.551 35.775 46.218 1.00 30.35 ? 603 VAL A CG1 1 ATOM 4596 C CG2 . VAL A 1 567 ? 49.274 37.556 45.073 1.00 25.97 ? 603 VAL A CG2 1 ATOM 4597 N N . GLU A 1 568 ? 49.359 33.102 44.370 1.00 32.04 ? 604 GLU A N 1 ATOM 4598 C CA . GLU A 1 568 ? 49.633 31.661 44.442 1.00 31.79 ? 604 GLU A CA 1 ATOM 4599 C C . GLU A 1 568 ? 50.370 31.137 43.213 1.00 34.47 ? 604 GLU A C 1 ATOM 4600 O O . GLU A 1 568 ? 51.278 30.309 43.331 1.00 31.15 ? 604 GLU A O 1 ATOM 4601 C CB . GLU A 1 568 ? 48.332 30.869 44.561 1.00 34.63 ? 604 GLU A CB 1 ATOM 4602 C CG . GLU A 1 568 ? 47.547 31.078 45.846 1.00 48.77 ? 604 GLU A CG 1 ATOM 4603 C CD . GLU A 1 568 ? 46.183 30.392 45.788 1.00 55.71 ? 604 GLU A CD 1 ATOM 4604 O OE1 . GLU A 1 568 ? 46.102 29.281 45.187 1.00 53.24 ? 604 GLU A OE1 1 ATOM 4605 O OE2 . GLU A 1 568 ? 45.201 30.981 46.315 1.00 48.31 ? 604 GLU A OE2 1 ATOM 4606 N N . ASP A 1 569 ? 49.963 31.591 42.029 1.00 29.98 ? 605 ASP A N 1 ATOM 4607 C CA . ASP A 1 569 ? 50.527 31.038 40.800 1.00 33.35 ? 605 ASP A CA 1 ATOM 4608 C C . ASP A 1 569 ? 51.965 31.482 40.550 1.00 30.33 ? 605 ASP A C 1 ATOM 4609 O O . ASP A 1 569 ? 52.760 30.716 40.003 1.00 30.11 ? 605 ASP A O 1 ATOM 4610 C CB . ASP A 1 569 ? 49.621 31.300 39.589 1.00 28.44 ? 605 ASP A CB 1 ATOM 4611 C CG . ASP A 1 569 ? 48.328 30.495 39.650 1.00 36.56 ? 605 ASP A CG 1 ATOM 4612 O OD1 . ASP A 1 569 ? 48.259 29.533 40.457 1.00 41.22 ? 605 ASP A OD1 1 ATOM 4613 O OD2 . ASP A 1 569 ? 47.379 30.810 38.896 1.00 36.09 ? 605 ASP A OD2 1 ATOM 4614 N N . GLN A 1 570 ? 52.305 32.702 40.966 1.00 29.55 ? 606 GLN A N 1 ATOM 4615 C CA . GLN A 1 570 ? 53.692 33.170 40.897 1.00 29.18 ? 606 GLN A CA 1 ATOM 4616 C C . GLN A 1 570 ? 54.565 32.292 41.783 1.00 31.62 ? 606 GLN A C 1 ATOM 4617 O O . GLN A 1 570 ? 55.682 31.918 41.403 1.00 33.23 ? 606 GLN A O 1 ATOM 4618 C CB . GLN A 1 570 ? 53.805 34.637 41.330 1.00 25.84 ? 606 GLN A CB 1 ATOM 4619 C CG . GLN A 1 570 ? 53.147 35.599 40.373 1.00 26.70 ? 606 GLN A CG 1 ATOM 4620 C CD . GLN A 1 570 ? 53.775 35.548 38.997 1.00 30.07 ? 606 GLN A CD 1 ATOM 4621 O OE1 . GLN A 1 570 ? 54.987 35.696 38.854 1.00 28.38 ? 606 GLN A OE1 1 ATOM 4622 N NE2 . GLN A 1 570 ? 52.950 35.351 37.972 1.00 27.55 ? 606 GLN A NE2 1 ATOM 4623 N N . ILE A 1 571 ? 54.054 31.956 42.965 1.00 28.82 ? 607 ILE A N 1 ATOM 4624 C CA . ILE A 1 571 ? 54.781 31.064 43.871 1.00 30.00 ? 607 ILE A CA 1 ATOM 4625 C C . ILE A 1 571 ? 54.979 29.673 43.237 1.00 32.12 ? 607 ILE A C 1 ATOM 4626 O O . ILE A 1 571 ? 56.095 29.148 43.197 1.00 35.32 ? 607 ILE A O 1 ATOM 4627 C CB . ILE A 1 571 ? 54.074 30.945 45.242 1.00 32.47 ? 607 ILE A CB 1 ATOM 4628 C CG1 . ILE A 1 571 ? 53.984 32.316 45.920 1.00 30.16 ? 607 ILE A CG1 1 ATOM 4629 C CG2 . ILE A 1 571 ? 54.832 29.979 46.157 1.00 34.62 ? 607 ILE A CG2 1 ATOM 4630 C CD1 . ILE A 1 571 ? 53.154 32.307 47.184 1.00 27.81 ? 607 ILE A CD1 1 ATOM 4631 N N . GLU A 1 572 ? 53.897 29.093 42.722 1.00 32.42 ? 608 GLU A N 1 ATOM 4632 C CA . GLU A 1 572 ? 53.963 27.765 42.112 1.00 36.29 ? 608 GLU A CA 1 ATOM 4633 C C . GLU A 1 572 ? 54.860 27.743 40.870 1.00 36.73 ? 608 GLU A C 1 ATOM 4634 O O . GLU A 1 572 ? 55.581 26.774 40.646 1.00 40.95 ? 608 GLU A O 1 ATOM 4635 C CB . GLU A 1 572 ? 52.563 27.223 41.811 1.00 36.46 ? 608 GLU A CB 1 ATOM 4636 C CG . GLU A 1 572 ? 52.554 25.890 41.044 1.00 45.25 ? 608 GLU A CG 1 ATOM 4637 C CD . GLU A 1 572 ? 53.208 24.741 41.817 1.00 51.17 ? 608 GLU A CD 1 ATOM 4638 O OE1 . GLU A 1 572 ? 53.235 24.790 43.065 1.00 53.05 ? 608 GLU A OE1 1 ATOM 4639 O OE2 . GLU A 1 572 ? 53.705 23.787 41.173 1.00 54.49 ? 608 GLU A OE2 1 ATOM 4640 N N . ALA A 1 573 ? 54.842 28.812 40.079 1.00 30.73 ? 609 ALA A N 1 ATOM 4641 C CA . ALA A 1 573 ? 55.779 28.934 38.962 1.00 35.46 ? 609 ALA A CA 1 ATOM 4642 C C . ALA A 1 573 ? 57.231 28.890 39.434 1.00 37.96 ? 609 ALA A C 1 ATOM 4643 O O . ALA A 1 573 ? 58.082 28.246 38.806 1.00 37.39 ? 609 ALA A O 1 ATOM 4644 C CB . ALA A 1 573 ? 55.541 30.215 38.207 1.00 35.61 ? 609 ALA A CB 1 ATOM 4645 N N . ALA A 1 574 ? 57.519 29.608 40.516 1.00 34.16 ? 610 ALA A N 1 ATOM 4646 C CA . ALA A 1 574 ? 58.854 29.580 41.107 1.00 35.51 ? 610 ALA A CA 1 ATOM 4647 C C . ALA A 1 574 ? 59.243 28.155 41.495 1.00 35.29 ? 610 ALA A C 1 ATOM 4648 O O . ALA A 1 574 ? 60.350 27.716 41.192 1.00 39.81 ? 610 ALA A O 1 ATOM 4649 C CB . ALA A 1 574 ? 58.937 30.515 42.320 1.00 34.61 ? 610 ALA A CB 1 ATOM 4650 N N . ARG A 1 575 ? 58.336 27.436 42.157 1.00 36.30 ? 611 ARG A N 1 ATOM 4651 C CA . ARG A 1 575 ? 58.581 26.028 42.501 1.00 39.44 ? 611 ARG A CA 1 ATOM 4652 C C . ARG A 1 575 ? 58.881 25.206 41.248 1.00 44.51 ? 611 ARG A C 1 ATOM 4653 O O . ARG A 1 575 ? 59.803 24.391 41.223 1.00 46.67 ? 611 ARG A O 1 ATOM 4654 C CB . ARG A 1 575 ? 57.377 25.402 43.219 1.00 41.77 ? 611 ARG A CB 1 ATOM 4655 C CG . ARG A 1 575 ? 57.068 25.968 44.587 1.00 43.17 ? 611 ARG A CG 1 ATOM 4656 C CD . ARG A 1 575 ? 55.996 25.146 45.296 1.00 44.79 ? 611 ARG A CD 1 ATOM 4657 N NE . ARG A 1 575 ? 55.580 25.754 46.561 1.00 44.12 ? 611 ARG A NE 1 ATOM 4658 C CZ . ARG A 1 575 ? 56.297 25.713 47.683 1.00 56.95 ? 611 ARG A CZ 1 ATOM 4659 N NH1 . ARG A 1 575 ? 57.480 25.096 47.699 1.00 53.34 ? 611 ARG A NH1 1 ATOM 4660 N NH2 . ARG A 1 575 ? 55.840 26.295 48.795 1.00 57.81 ? 611 ARG A NH2 1 ATOM 4661 N N . GLN A 1 576 ? 58.078 25.416 40.211 1.00 42.50 ? 612 GLN A N 1 ATOM 4662 C CA . GLN A 1 576 ? 58.271 24.727 38.948 1.00 45.87 ? 612 GLN A CA 1 ATOM 4663 C C . GLN A 1 576 ? 59.664 25.020 38.430 1.00 46.31 ? 612 GLN A C 1 ATOM 4664 O O . GLN A 1 576 ? 60.382 24.115 38.009 1.00 49.43 ? 612 GLN A O 1 ATOM 4665 C CB . GLN A 1 576 ? 57.235 25.196 37.931 1.00 44.20 ? 612 GLN A CB 1 ATOM 4666 C CG . GLN A 1 576 ? 55.827 24.727 38.229 1.00 48.60 ? 612 GLN A CG 1 ATOM 4667 C CD . GLN A 1 576 ? 55.651 23.260 37.920 1.00 55.95 ? 612 GLN A CD 1 ATOM 4668 O OE1 . GLN A 1 576 ? 55.512 22.874 36.758 1.00 53.46 ? 612 GLN A OE1 1 ATOM 4669 N NE2 . GLN A 1 576 ? 55.682 22.426 38.956 1.00 54.71 ? 612 GLN A NE2 1 ATOM 4670 N N . PHE A 1 577 ? 60.046 26.292 38.468 1.00 41.63 ? 613 PHE A N 1 ATOM 4671 C CA . PHE A 1 577 ? 61.330 26.706 37.919 1.00 44.41 ? 613 PHE A CA 1 ATOM 4672 C C . PHE A 1 577 ? 62.496 26.047 38.662 1.00 46.77 ? 613 PHE A C 1 ATOM 4673 O O . PHE A 1 577 ? 63.489 25.686 38.044 1.00 49.22 ? 613 PHE A O 1 ATOM 4674 C CB . PHE A 1 577 ? 61.466 28.239 37.911 1.00 40.37 ? 613 PHE A CB 1 ATOM 4675 C CG . PHE A 1 577 ? 60.483 28.937 36.993 1.00 41.48 ? 613 PHE A CG 1 ATOM 4676 C CD1 . PHE A 1 577 ? 59.851 28.244 35.970 1.00 38.61 ? 613 PHE A CD1 1 ATOM 4677 C CD2 . PHE A 1 577 ? 60.190 30.283 37.161 1.00 37.86 ? 613 PHE A CD2 1 ATOM 4678 C CE1 . PHE A 1 577 ? 58.936 28.883 35.133 1.00 42.42 ? 613 PHE A CE1 1 ATOM 4679 C CE2 . PHE A 1 577 ? 59.287 30.930 36.333 1.00 33.76 ? 613 PHE A CE2 1 ATOM 4680 C CZ . PHE A 1 577 ? 58.658 30.231 35.315 1.00 37.49 ? 613 PHE A CZ 1 ATOM 4681 N N . SER A 1 578 ? 62.365 25.887 39.980 1.00 47.19 ? 614 SER A N 1 ATOM 4682 C CA . SER A 1 578 ? 63.383 25.204 40.787 1.00 46.55 ? 614 SER A CA 1 ATOM 4683 C C . SER A 1 578 ? 63.564 23.754 40.358 1.00 55.49 ? 614 SER A C 1 ATOM 4684 O O . SER A 1 578 ? 64.684 23.267 40.218 1.00 62.33 ? 614 SER A O 1 ATOM 4685 C CB . SER A 1 578 ? 63.006 25.233 42.264 1.00 47.61 ? 614 SER A CB 1 ATOM 4686 O OG . SER A 1 578 ? 62.872 26.560 42.724 1.00 46.83 ? 614 SER A OG 1 ATOM 4687 N N . LYS A 1 579 ? 62.451 23.060 40.157 1.00 57.17 ? 615 LYS A N 1 ATOM 4688 C CA . LYS A 1 579 ? 62.487 21.646 39.803 1.00 59.00 ? 615 LYS A CA 1 ATOM 4689 C C . LYS A 1 579 ? 63.213 21.413 38.476 1.00 62.13 ? 615 LYS A C 1 ATOM 4690 O O . LYS A 1 579 ? 63.585 20.282 38.159 1.00 65.58 ? 615 LYS A O 1 ATOM 4691 C CB . LYS A 1 579 ? 61.068 21.057 39.785 1.00 60.54 ? 615 LYS A CB 1 ATOM 4692 C CG . LYS A 1 579 ? 60.448 20.936 41.186 1.00 63.19 ? 615 LYS A CG 1 ATOM 4693 C CD . LYS A 1 579 ? 58.920 20.824 41.159 1.00 62.88 ? 615 LYS A CD 1 ATOM 4694 C CE . LYS A 1 579 ? 58.356 20.903 42.581 1.00 66.97 ? 615 LYS A CE 1 ATOM 4695 N NZ . LYS A 1 579 ? 56.870 21.078 42.630 1.00 69.55 ? 615 LYS A NZ 1 ATOM 4696 N N . MET A 1 580 ? 63.406 22.484 37.705 1.00 59.25 ? 616 MET A N 1 ATOM 4697 C CA . MET A 1 580 ? 64.274 22.445 36.530 1.00 57.11 ? 616 MET A CA 1 ATOM 4698 C C . MET A 1 580 ? 65.723 22.498 37.023 1.00 55.79 ? 616 MET A C 1 ATOM 4699 O O . MET A 1 580 ? 66.037 23.215 37.973 1.00 60.07 ? 616 MET A O 1 ATOM 4700 C CB . MET A 1 580 ? 63.977 23.621 35.595 1.00 55.26 ? 616 MET A CB 1 ATOM 4701 C CG . MET A 1 580 ? 62.533 23.695 35.098 1.00 51.74 ? 616 MET A CG 1 ATOM 4702 S SD . MET A 1 580 ? 62.160 25.249 34.236 1.00 56.54 ? 616 MET A SD 1 ATOM 4703 C CE . MET A 1 580 ? 60.495 24.926 33.661 1.00 47.09 ? 616 MET A CE 1 ATOM 4704 N N . GLY A 1 581 ? 66.608 21.746 36.384 1.00 54.68 ? 617 GLY A N 1 ATOM 4705 C CA . GLY A 1 581 ? 67.922 21.505 36.954 1.00 49.55 ? 617 GLY A CA 1 ATOM 4706 C C . GLY A 1 581 ? 68.941 22.624 36.868 1.00 49.76 ? 617 GLY A C 1 ATOM 4707 O O . GLY A 1 581 ? 70.065 22.473 37.343 1.00 51.97 ? 617 GLY A O 1 ATOM 4708 N N . PHE A 1 582 ? 68.571 23.747 36.266 1.00 44.22 ? 618 PHE A N 1 ATOM 4709 C CA . PHE A 1 582 ? 69.531 24.827 36.082 1.00 43.25 ? 618 PHE A CA 1 ATOM 4710 C C . PHE A 1 582 ? 69.269 26.052 36.969 1.00 44.81 ? 618 PHE A C 1 ATOM 4711 O O . PHE A 1 582 ? 69.802 27.142 36.703 1.00 40.54 ? 618 PHE A O 1 ATOM 4712 C CB . PHE A 1 582 ? 69.599 25.244 34.609 1.00 44.57 ? 618 PHE A CB 1 ATOM 4713 C CG . PHE A 1 582 ? 68.261 25.534 33.996 1.00 45.92 ? 618 PHE A CG 1 ATOM 4714 C CD1 . PHE A 1 582 ? 67.644 26.758 34.194 1.00 44.86 ? 618 PHE A CD1 1 ATOM 4715 C CD2 . PHE A 1 582 ? 67.626 24.590 33.212 1.00 45.54 ? 618 PHE A CD2 1 ATOM 4716 C CE1 . PHE A 1 582 ? 66.420 27.030 33.632 1.00 41.48 ? 618 PHE A CE1 1 ATOM 4717 C CE2 . PHE A 1 582 ? 66.396 24.862 32.645 1.00 48.12 ? 618 PHE A CE2 1 ATOM 4718 C CZ . PHE A 1 582 ? 65.795 26.082 32.856 1.00 45.87 ? 618 PHE A CZ 1 ATOM 4719 N N . VAL A 1 583 ? 68.457 25.860 38.010 1.00 41.84 ? 619 VAL A N 1 ATOM 4720 C CA . VAL A 1 583 ? 68.119 26.917 38.964 1.00 40.63 ? 619 VAL A CA 1 ATOM 4721 C C . VAL A 1 583 ? 68.607 26.606 40.385 1.00 41.42 ? 619 VAL A C 1 ATOM 4722 O O . VAL A 1 583 ? 68.287 25.566 40.961 1.00 42.06 ? 619 VAL A O 1 ATOM 4723 C CB . VAL A 1 583 ? 66.592 27.185 38.999 1.00 41.84 ? 619 VAL A CB 1 ATOM 4724 C CG1 . VAL A 1 583 ? 66.254 28.259 40.023 1.00 41.55 ? 619 VAL A CG1 1 ATOM 4725 C CG2 . VAL A 1 583 ? 66.100 27.601 37.635 1.00 40.96 ? 619 VAL A CG2 1 ATOM 4726 N N . ASP A 1 584 ? 69.388 27.525 40.937 1.00 41.64 ? 620 ASP A N 1 ATOM 4727 C CA . ASP A 1 584 ? 69.834 27.444 42.326 1.00 40.81 ? 620 ASP A CA 1 ATOM 4728 C C . ASP A 1 584 ? 68.690 27.857 43.236 1.00 40.50 ? 620 ASP A C 1 ATOM 4729 O O . ASP A 1 584 ? 68.390 29.044 43.350 1.00 41.59 ? 620 ASP A O 1 ATOM 4730 C CB . ASP A 1 584 ? 71.017 28.388 42.530 1.00 38.31 ? 620 ASP A CB 1 ATOM 4731 C CG . ASP A 1 584 ? 71.528 28.399 43.959 1.00 42.86 ? 620 ASP A CG 1 ATOM 4732 O OD1 . ASP A 1 584 ? 70.999 27.641 44.801 1.00 44.93 ? 620 ASP A OD1 1 ATOM 4733 O OD2 . ASP A 1 584 ? 72.477 29.164 44.233 1.00 43.71 ? 620 ASP A OD2 1 ATOM 4734 N N . ASN A 1 585 ? 68.040 26.901 43.887 1.00 38.68 ? 621 ASN A N 1 ATOM 4735 C CA . ASN A 1 585 ? 66.847 27.250 44.666 1.00 41.40 ? 621 ASN A CA 1 ATOM 4736 C C . ASN A 1 585 ? 67.114 28.007 45.974 1.00 42.71 ? 621 ASN A C 1 ATOM 4737 O O . ASN A 1 585 ? 66.169 28.435 46.661 1.00 36.46 ? 621 ASN A O 1 ATOM 4738 C CB . ASN A 1 585 ? 65.927 26.040 44.883 1.00 48.11 ? 621 ASN A CB 1 ATOM 4739 C CG . ASN A 1 585 ? 66.686 24.791 45.251 1.00 52.49 ? 621 ASN A CG 1 ATOM 4740 O OD1 . ASN A 1 585 ? 66.898 23.909 44.412 1.00 58.94 ? 621 ASN A OD1 1 ATOM 4741 N ND2 . ASN A 1 585 ? 67.102 24.701 46.510 1.00 49.33 ? 621 ASN A ND2 1 ATOM 4742 N N . LYS A 1 586 ? 68.395 28.186 46.302 1.00 41.73 ? 622 LYS A N 1 ATOM 4743 C CA . LYS A 1 586 ? 68.780 29.016 47.440 1.00 38.28 ? 622 LYS A CA 1 ATOM 4744 C C . LYS A 1 586 ? 68.913 30.486 47.024 1.00 39.19 ? 622 LYS A C 1 ATOM 4745 O O . LYS A 1 586 ? 69.051 31.378 47.863 1.00 37.33 ? 622 LYS A O 1 ATOM 4746 C CB . LYS A 1 586 ? 70.082 28.507 48.064 1.00 43.19 ? 622 LYS A CB 1 ATOM 4747 C CG . LYS A 1 586 ? 69.908 27.274 48.941 1.00 48.65 ? 622 LYS A CG 1 ATOM 4748 C CD . LYS A 1 586 ? 71.005 26.239 48.682 1.00 54.87 ? 622 LYS A CD 1 ATOM 4749 C CE . LYS A 1 586 ? 72.389 26.879 48.551 1.00 57.15 ? 622 LYS A CE 1 ATOM 4750 N NZ . LYS A 1 586 ? 72.817 27.038 47.116 1.00 57.66 ? 622 LYS A NZ 1 ATOM 4751 N N . ARG A 1 587 ? 68.866 30.740 45.722 1.00 36.51 ? 623 ARG A N 1 ATOM 4752 C CA . ARG A 1 587 ? 68.929 32.109 45.235 1.00 33.44 ? 623 ARG A CA 1 ATOM 4753 C C . ARG A 1 587 ? 67.817 32.436 44.249 1.00 34.72 ? 623 ARG A C 1 ATOM 4754 O O . ARG A 1 587 ? 68.059 32.600 43.062 1.00 29.06 ? 623 ARG A O 1 ATOM 4755 C CB . ARG A 1 587 ? 70.304 32.417 44.649 1.00 33.63 ? 623 ARG A CB 1 ATOM 4756 C CG . ARG A 1 587 ? 71.404 32.494 45.723 1.00 36.70 ? 623 ARG A CG 1 ATOM 4757 C CD . ARG A 1 587 ? 72.752 32.811 45.102 1.00 37.22 ? 623 ARG A CD 1 ATOM 4758 N NE . ARG A 1 587 ? 73.145 31.795 44.131 1.00 34.84 ? 623 ARG A NE 1 ATOM 4759 C CZ . ARG A 1 587 ? 74.053 31.985 43.180 1.00 38.27 ? 623 ARG A CZ 1 ATOM 4760 N NH1 . ARG A 1 587 ? 74.648 33.160 43.065 1.00 33.92 ? 623 ARG A NH1 1 ATOM 4761 N NH2 . ARG A 1 587 ? 74.362 31.003 42.334 1.00 39.01 ? 623 ARG A NH2 1 ATOM 4762 N N . ILE A 1 588 ? 66.597 32.538 44.767 1.00 33.83 ? 624 ILE A N 1 ATOM 4763 C CA . ILE A 1 588 ? 65.449 32.990 43.990 1.00 32.80 ? 624 ILE A CA 1 ATOM 4764 C C . ILE A 1 588 ? 64.925 34.290 44.600 1.00 32.12 ? 624 ILE A C 1 ATOM 4765 O O . ILE A 1 588 ? 64.653 34.354 45.803 1.00 32.79 ? 624 ILE A O 1 ATOM 4766 C CB . ILE A 1 588 ? 64.321 31.939 43.994 1.00 34.41 ? 624 ILE A CB 1 ATOM 4767 C CG1 . ILE A 1 588 ? 64.848 30.591 43.500 1.00 37.32 ? 624 ILE A CG1 1 ATOM 4768 C CG2 . ILE A 1 588 ? 63.155 32.384 43.108 1.00 32.43 ? 624 ILE A CG2 1 ATOM 4769 C CD1 . ILE A 1 588 ? 63.772 29.548 43.382 1.00 41.48 ? 624 ILE A CD1 1 ATOM 4770 N N . ALA A 1 589 ? 64.805 35.321 43.769 1.00 27.73 ? 625 ALA A N 1 ATOM 4771 C CA . ALA A 1 589 ? 64.290 36.620 44.182 1.00 26.56 ? 625 ALA A CA 1 ATOM 4772 C C . ALA A 1 589 ? 63.036 36.953 43.381 1.00 27.73 ? 625 ALA A C 1 ATOM 4773 O O . ALA A 1 589 ? 62.685 36.234 42.452 1.00 25.59 ? 625 ALA A O 1 ATOM 4774 C CB . ALA A 1 589 ? 65.342 37.691 43.971 1.00 26.53 ? 625 ALA A CB 1 ATOM 4775 N N . ILE A 1 590 ? 62.379 38.053 43.731 1.00 27.11 ? 626 ILE A N 1 ATOM 4776 C CA . ILE A 1 590 ? 61.151 38.476 43.059 1.00 24.56 ? 626 ILE A CA 1 ATOM 4777 C C . ILE A 1 590 ? 61.062 39.992 43.124 1.00 26.03 ? 626 ILE A C 1 ATOM 4778 O O . ILE A 1 590 ? 61.434 40.596 44.129 1.00 28.77 ? 626 ILE A O 1 ATOM 4779 C CB . ILE A 1 590 ? 59.898 37.832 43.710 1.00 25.08 ? 626 ILE A CB 1 ATOM 4780 C CG1 . ILE A 1 590 ? 58.619 38.250 42.990 1.00 29.19 ? 626 ILE A CG1 1 ATOM 4781 C CG2 . ILE A 1 590 ? 59.793 38.205 45.193 1.00 27.02 ? 626 ILE A CG2 1 ATOM 4782 C CD1 . ILE A 1 590 ? 57.368 37.564 43.549 1.00 30.66 ? 626 ILE A CD1 1 ATOM 4783 N N . TRP A 1 591 ? 60.594 40.623 42.055 1.00 24.12 ? 627 TRP A N 1 ATOM 4784 C CA . TRP A 1 591 ? 60.421 42.072 42.068 1.00 24.66 ? 627 TRP A CA 1 ATOM 4785 C C . TRP A 1 591 ? 59.300 42.451 41.129 1.00 28.34 ? 627 TRP A C 1 ATOM 4786 O O . TRP A 1 591 ? 58.985 41.712 40.180 1.00 23.46 ? 627 TRP A O 1 ATOM 4787 C CB . TRP A 1 591 ? 61.719 42.806 41.691 1.00 25.61 ? 627 TRP A CB 1 ATOM 4788 C CG . TRP A 1 591 ? 61.869 43.191 40.226 1.00 26.45 ? 627 TRP A CG 1 ATOM 4789 C CD1 . TRP A 1 591 ? 62.214 42.364 39.188 1.00 26.42 ? 627 TRP A CD1 1 ATOM 4790 C CD2 . TRP A 1 591 ? 61.722 44.504 39.653 1.00 27.44 ? 627 TRP A CD2 1 ATOM 4791 N NE1 . TRP A 1 591 ? 62.271 43.079 38.007 1.00 26.35 ? 627 TRP A NE1 1 ATOM 4792 C CE2 . TRP A 1 591 ? 61.972 44.389 38.265 1.00 26.05 ? 627 TRP A CE2 1 ATOM 4793 C CE3 . TRP A 1 591 ? 61.386 45.757 40.174 1.00 28.70 ? 627 TRP A CE3 1 ATOM 4794 C CZ2 . TRP A 1 591 ? 61.910 45.482 37.398 1.00 28.87 ? 627 TRP A CZ2 1 ATOM 4795 C CZ3 . TRP A 1 591 ? 61.325 46.845 39.313 1.00 27.29 ? 627 TRP A CZ3 1 ATOM 4796 C CH2 . TRP A 1 591 ? 61.578 46.699 37.937 1.00 32.10 ? 627 TRP A CH2 1 ATOM 4797 N N . GLY A 1 592 ? 58.688 43.595 41.407 1.00 25.76 ? 628 GLY A N 1 ATOM 4798 C CA . GLY A 1 592 ? 57.599 44.088 40.592 1.00 25.20 ? 628 GLY A CA 1 ATOM 4799 C C . GLY A 1 592 ? 57.345 45.539 40.917 1.00 27.24 ? 628 GLY A C 1 ATOM 4800 O O . GLY A 1 592 ? 57.761 46.032 41.971 1.00 23.97 ? 628 GLY A O 1 ATOM 4801 N N . TRP A 1 593 ? 56.650 46.215 40.013 1.00 26.54 ? 629 TRP A N 1 ATOM 4802 C CA . TRP A 1 593 ? 56.359 47.627 40.131 1.00 25.16 ? 629 TRP A CA 1 ATOM 4803 C C . TRP A 1 593 ? 54.849 47.749 40.037 1.00 27.20 ? 629 TRP A C 1 ATOM 4804 O O . TRP A 1 593 ? 54.215 47.057 39.229 1.00 27.73 ? 629 TRP A O 1 ATOM 4805 C CB . TRP A 1 593 ? 57.005 48.348 38.948 1.00 28.72 ? 629 TRP A CB 1 ATOM 4806 C CG . TRP A 1 593 ? 57.194 49.841 39.077 1.00 26.50 ? 629 TRP A CG 1 ATOM 4807 C CD1 . TRP A 1 593 ? 56.239 50.775 39.348 1.00 28.60 ? 629 TRP A CD1 1 ATOM 4808 C CD2 . TRP A 1 593 ? 58.416 50.569 38.856 1.00 25.82 ? 629 TRP A CD2 1 ATOM 4809 N NE1 . TRP A 1 593 ? 56.798 52.041 39.349 1.00 28.92 ? 629 TRP A NE1 1 ATOM 4810 C CE2 . TRP A 1 593 ? 58.130 51.938 39.040 1.00 27.51 ? 629 TRP A CE2 1 ATOM 4811 C CE3 . TRP A 1 593 ? 59.727 50.191 38.544 1.00 25.20 ? 629 TRP A CE3 1 ATOM 4812 C CZ2 . TRP A 1 593 ? 59.105 52.930 38.914 1.00 27.18 ? 629 TRP A CZ2 1 ATOM 4813 C CZ3 . TRP A 1 593 ? 60.697 51.180 38.422 1.00 25.09 ? 629 TRP A CZ3 1 ATOM 4814 C CH2 . TRP A 1 593 ? 60.380 52.531 38.607 1.00 27.18 ? 629 TRP A CH2 1 ATOM 4815 N N . SER A 1 594 ? 54.268 48.613 40.864 1.00 25.20 ? 630 SER A N 1 ATOM 4816 C CA . SER A 1 594 ? 52.844 48.894 40.780 1.00 24.97 ? 630 SER A CA 1 ATOM 4817 C C . SER A 1 594 ? 52.048 47.644 41.186 1.00 26.89 ? 630 SER A C 1 ATOM 4818 O O . SER A 1 594 ? 52.262 47.098 42.264 1.00 27.88 ? 630 SER A O 1 ATOM 4819 C CB . SER A 1 594 ? 52.519 49.359 39.355 1.00 28.32 ? 630 SER A CB 1 ATOM 4820 O OG . SER A 1 594 ? 51.333 50.113 39.346 1.00 34.33 ? 630 SER A OG 1 ATOM 4821 N N . TYR A 1 595 ? 51.146 47.167 40.342 1.00 26.91 ? 631 TYR A N 1 ATOM 4822 C CA . TYR A 1 595 ? 50.474 45.919 40.659 1.00 25.03 ? 631 TYR A CA 1 ATOM 4823 C C . TYR A 1 595 ? 51.504 44.834 40.954 1.00 24.83 ? 631 TYR A C 1 ATOM 4824 O O . TYR A 1 595 ? 51.313 44.012 41.841 1.00 24.89 ? 631 TYR A O 1 ATOM 4825 C CB . TYR A 1 595 ? 49.548 45.469 39.527 1.00 23.47 ? 631 TYR A CB 1 ATOM 4826 C CG . TYR A 1 595 ? 48.512 44.451 39.982 1.00 25.54 ? 631 TYR A CG 1 ATOM 4827 C CD1 . TYR A 1 595 ? 48.848 43.110 40.160 1.00 25.46 ? 631 TYR A CD1 1 ATOM 4828 C CD2 . TYR A 1 595 ? 47.199 44.835 40.244 1.00 27.49 ? 631 TYR A CD2 1 ATOM 4829 C CE1 . TYR A 1 595 ? 47.913 42.176 40.583 1.00 23.77 ? 631 TYR A CE1 1 ATOM 4830 C CE2 . TYR A 1 595 ? 46.252 43.906 40.676 1.00 26.98 ? 631 TYR A CE2 1 ATOM 4831 C CZ . TYR A 1 595 ? 46.625 42.579 40.844 1.00 25.37 ? 631 TYR A CZ 1 ATOM 4832 O OH . TYR A 1 595 ? 45.694 41.657 41.252 1.00 30.40 ? 631 TYR A OH 1 ATOM 4833 N N . GLY A 1 596 ? 52.607 44.827 40.216 1.00 23.32 ? 632 GLY A N 1 ATOM 4834 C CA . GLY A 1 596 ? 53.655 43.857 40.494 1.00 24.86 ? 632 GLY A CA 1 ATOM 4835 C C . GLY A 1 596 ? 54.288 44.037 41.874 1.00 26.04 ? 632 GLY A C 1 ATOM 4836 O O . GLY A 1 596 ? 54.761 43.073 42.483 1.00 27.16 ? 632 GLY A O 1 ATOM 4837 N N . GLY A 1 597 ? 54.305 45.272 42.370 1.00 24.03 ? 633 GLY A N 1 ATOM 4838 C CA . GLY A 1 597 ? 54.879 45.551 43.682 1.00 24.65 ? 633 GLY A CA 1 ATOM 4839 C C . GLY A 1 597 ? 53.950 44.994 44.746 1.00 22.38 ? 633 GLY A C 1 ATOM 4840 O O . GLY A 1 597 ? 54.384 44.429 45.741 1.00 25.83 ? 633 GLY A O 1 ATOM 4841 N N . TYR A 1 598 ? 52.652 45.109 44.498 1.00 26.07 ? 634 TYR A N 1 ATOM 4842 C CA . TYR A 1 598 ? 51.651 44.471 45.347 1.00 25.16 ? 634 TYR A CA 1 ATOM 4843 C C . TYR A 1 598 ? 51.825 42.949 45.355 1.00 25.28 ? 634 TYR A C 1 ATOM 4844 O O . TYR A 1 598 ? 51.921 42.323 46.412 1.00 24.00 ? 634 TYR A O 1 ATOM 4845 C CB . TYR A 1 598 ? 50.250 44.841 44.849 1.00 27.69 ? 634 TYR A CB 1 ATOM 4846 C CG . TYR A 1 598 ? 49.119 44.079 45.512 1.00 27.69 ? 634 TYR A CG 1 ATOM 4847 C CD1 . TYR A 1 598 ? 48.776 44.322 46.832 1.00 23.75 ? 634 TYR A CD1 1 ATOM 4848 C CD2 . TYR A 1 598 ? 48.375 43.143 44.796 1.00 27.27 ? 634 TYR A CD2 1 ATOM 4849 C CE1 . TYR A 1 598 ? 47.724 43.632 47.441 1.00 30.00 ? 634 TYR A CE1 1 ATOM 4850 C CE2 . TYR A 1 598 ? 47.328 42.448 45.381 1.00 29.54 ? 634 TYR A CE2 1 ATOM 4851 C CZ . TYR A 1 598 ? 47.004 42.698 46.704 1.00 29.63 ? 634 TYR A CZ 1 ATOM 4852 O OH . TYR A 1 598 ? 45.964 42.011 47.274 1.00 27.52 ? 634 TYR A OH 1 ATOM 4853 N N . VAL A 1 599 ? 51.858 42.344 44.172 1.00 26.74 ? 635 VAL A N 1 ATOM 4854 C CA . VAL A 1 599 ? 52.001 40.899 44.098 1.00 23.90 ? 635 VAL A CA 1 ATOM 4855 C C . VAL A 1 599 ? 53.321 40.443 44.721 1.00 24.67 ? 635 VAL A C 1 ATOM 4856 O O . VAL A 1 599 ? 53.352 39.467 45.463 1.00 23.65 ? 635 VAL A O 1 ATOM 4857 C CB . VAL A 1 599 ? 51.898 40.395 42.660 1.00 25.10 ? 635 VAL A CB 1 ATOM 4858 C CG1 . VAL A 1 599 ? 52.314 38.936 42.586 1.00 27.66 ? 635 VAL A CG1 1 ATOM 4859 C CG2 . VAL A 1 599 ? 50.467 40.612 42.121 1.00 24.25 ? 635 VAL A CG2 1 ATOM 4860 N N . THR A 1 600 ? 54.406 41.152 44.427 1.00 24.20 ? 636 THR A N 1 ATOM 4861 C CA . THR A 1 600 ? 55.691 40.837 45.052 1.00 25.91 ? 636 THR A CA 1 ATOM 4862 C C . THR A 1 600 ? 55.590 40.817 46.574 1.00 25.57 ? 636 THR A C 1 ATOM 4863 O O . THR A 1 600 ? 56.151 39.932 47.239 1.00 28.73 ? 636 THR A O 1 ATOM 4864 C CB . THR A 1 600 ? 56.772 41.843 44.659 1.00 26.32 ? 636 THR A CB 1 ATOM 4865 O OG1 . THR A 1 600 ? 57.111 41.652 43.286 1.00 28.25 ? 636 THR A OG1 1 ATOM 4866 C CG2 . THR A 1 600 ? 58.019 41.621 45.498 1.00 28.57 ? 636 THR A CG2 1 ATOM 4867 N N . SER A 1 601 ? 54.886 41.794 47.136 1.00 25.31 ? 637 SER A N 1 ATOM 4868 C CA . SER A 1 601 ? 54.775 41.897 48.595 1.00 26.16 ? 637 SER A CA 1 ATOM 4869 C C . SER A 1 601 ? 53.930 40.769 49.171 1.00 27.87 ? 637 SER A C 1 ATOM 4870 O O . SER A 1 601 ? 54.270 40.183 50.194 1.00 25.16 ? 637 SER A O 1 ATOM 4871 C CB . SER A 1 601 ? 54.192 43.247 48.998 1.00 26.77 ? 637 SER A CB 1 ATOM 4872 O OG . SER A 1 601 ? 55.013 44.304 48.531 1.00 26.41 ? 637 SER A OG 1 ATOM 4873 N N . MET A 1 602 ? 52.826 40.465 48.502 1.00 27.40 ? 638 MET A N 1 ATOM 4874 C CA . MET A 1 602 ? 51.946 39.392 48.935 1.00 26.16 ? 638 MET A CA 1 ATOM 4875 C C . MET A 1 602 ? 52.702 38.072 48.907 1.00 27.82 ? 638 MET A C 1 ATOM 4876 O O . MET A 1 602 ? 52.567 37.256 49.820 1.00 29.54 ? 638 MET A O 1 ATOM 4877 C CB . MET A 1 602 ? 50.703 39.343 48.047 1.00 27.08 ? 638 MET A CB 1 ATOM 4878 C CG . MET A 1 602 ? 49.824 40.575 48.183 1.00 27.34 ? 638 MET A CG 1 ATOM 4879 S SD . MET A 1 602 ? 48.959 40.599 49.774 1.00 30.50 ? 638 MET A SD 1 ATOM 4880 C CE . MET A 1 602 ? 47.686 39.360 49.476 1.00 30.36 ? 638 MET A CE 1 ATOM 4881 N N . VAL A 1 603 ? 53.531 37.883 47.876 1.00 26.32 ? 639 VAL A N 1 ATOM 4882 C CA . VAL A 1 603 ? 54.344 36.669 47.757 1.00 27.06 ? 639 VAL A CA 1 ATOM 4883 C C . VAL A 1 603 ? 55.392 36.564 48.865 1.00 28.63 ? 639 VAL A C 1 ATOM 4884 O O . VAL A 1 603 ? 55.551 35.516 49.477 1.00 30.98 ? 639 VAL A O 1 ATOM 4885 C CB . VAL A 1 603 ? 55.059 36.584 46.389 1.00 27.79 ? 639 VAL A CB 1 ATOM 4886 C CG1 . VAL A 1 603 ? 56.104 35.489 46.403 1.00 24.63 ? 639 VAL A CG1 1 ATOM 4887 C CG2 . VAL A 1 603 ? 54.057 36.334 45.280 1.00 26.18 ? 639 VAL A CG2 1 ATOM 4888 N N . LEU A 1 604 ? 56.116 37.647 49.119 1.00 30.61 ? 640 LEU A N 1 ATOM 4889 C CA . LEU A 1 604 ? 57.103 37.648 50.198 1.00 31.38 ? 640 LEU A CA 1 ATOM 4890 C C . LEU A 1 604 ? 56.434 37.426 51.550 1.00 30.09 ? 640 LEU A C 1 ATOM 4891 O O . LEU A 1 604 ? 57.039 36.886 52.479 1.00 33.21 ? 640 LEU A O 1 ATOM 4892 C CB . LEU A 1 604 ? 57.888 38.959 50.204 1.00 29.69 ? 640 LEU A CB 1 ATOM 4893 C CG . LEU A 1 604 ? 58.778 39.170 48.978 1.00 29.41 ? 640 LEU A CG 1 ATOM 4894 C CD1 . LEU A 1 604 ? 59.396 40.552 49.021 1.00 27.90 ? 640 LEU A CD1 1 ATOM 4895 C CD2 . LEU A 1 604 ? 59.874 38.089 48.878 1.00 26.75 ? 640 LEU A CD2 1 ATOM 4896 N N . GLY A 1 605 ? 55.175 37.839 51.650 1.00 29.97 ? 641 GLY A N 1 ATOM 4897 C CA . GLY A 1 605 ? 54.436 37.718 52.889 1.00 31.87 ? 641 GLY A CA 1 ATOM 4898 C C . GLY A 1 605 ? 53.646 36.428 53.023 1.00 31.78 ? 641 GLY A C 1 ATOM 4899 O O . GLY A 1 605 ? 52.916 36.259 53.987 1.00 30.62 ? 641 GLY A O 1 ATOM 4900 N N . SER A 1 606 ? 53.787 35.517 52.060 1.00 34.64 ? 642 SER A N 1 ATOM 4901 C CA . SER A 1 606 ? 53.007 34.282 52.067 1.00 31.19 ? 642 SER A CA 1 ATOM 4902 C C . SER A 1 606 ? 53.610 33.235 52.992 1.00 31.75 ? 642 SER A C 1 ATOM 4903 O O . SER A 1 606 ? 52.936 32.283 53.368 1.00 35.71 ? 642 SER A O 1 ATOM 4904 C CB . SER A 1 606 ? 52.928 33.689 50.662 1.00 31.42 ? 642 SER A CB 1 ATOM 4905 O OG . SER A 1 606 ? 54.181 33.126 50.296 1.00 31.85 ? 642 SER A OG 1 ATOM 4906 N N . GLY A 1 607 ? 54.884 33.393 53.333 1.00 29.72 ? 643 GLY A N 1 ATOM 4907 C CA . GLY A 1 607 ? 55.573 32.418 54.164 1.00 34.79 ? 643 GLY A CA 1 ATOM 4908 C C . GLY A 1 607 ? 55.885 31.131 53.419 1.00 40.84 ? 643 GLY A C 1 ATOM 4909 O O . GLY A 1 607 ? 56.024 30.067 54.020 1.00 39.44 ? 643 GLY A O 1 ATOM 4910 N N . SER A 1 608 ? 56.012 31.233 52.100 1.00 34.64 ? 644 SER A N 1 ATOM 4911 C CA . SER A 1 608 ? 56.158 30.059 51.258 1.00 34.80 ? 644 SER A CA 1 ATOM 4912 C C . SER A 1 608 ? 57.550 29.452 51.372 1.00 36.61 ? 644 SER A C 1 ATOM 4913 O O . SER A 1 608 ? 57.744 28.267 51.085 1.00 38.43 ? 644 SER A O 1 ATOM 4914 C CB . SER A 1 608 ? 55.881 30.431 49.804 1.00 31.17 ? 644 SER A CB 1 ATOM 4915 O OG . SER A 1 608 ? 57.033 31.031 49.234 1.00 33.13 ? 644 SER A OG 1 ATOM 4916 N N . GLY A 1 609 ? 58.519 30.267 51.777 1.00 30.53 ? 645 GLY A N 1 ATOM 4917 C CA . GLY A 1 609 ? 59.899 29.819 51.870 1.00 35.83 ? 645 GLY A CA 1 ATOM 4918 C C . GLY A 1 609 ? 60.631 29.695 50.535 1.00 34.17 ? 645 GLY A C 1 ATOM 4919 O O . GLY A 1 609 ? 61.803 29.320 50.490 1.00 34.70 ? 645 GLY A O 1 ATOM 4920 N N . VAL A 1 610 ? 59.965 30.026 49.436 1.00 35.24 ? 646 VAL A N 1 ATOM 4921 C CA . VAL A 1 610 ? 60.595 29.859 48.123 1.00 31.88 ? 646 VAL A CA 1 ATOM 4922 C C . VAL A 1 610 ? 61.578 30.987 47.793 1.00 36.05 ? 646 VAL A C 1 ATOM 4923 O O . VAL A 1 610 ? 62.584 30.761 47.106 1.00 37.71 ? 646 VAL A O 1 ATOM 4924 C CB . VAL A 1 610 ? 59.543 29.725 46.985 1.00 33.74 ? 646 VAL A CB 1 ATOM 4925 C CG1 . VAL A 1 610 ? 60.223 29.738 45.619 1.00 30.48 ? 646 VAL A CG1 1 ATOM 4926 C CG2 . VAL A 1 610 ? 58.731 28.462 47.159 1.00 34.96 ? 646 VAL A CG2 1 ATOM 4927 N N . PHE A 1 611 ? 61.292 32.190 48.293 1.00 30.04 ? 647 PHE A N 1 ATOM 4928 C CA . PHE A 1 611 ? 62.035 33.384 47.896 1.00 30.41 ? 647 PHE A CA 1 ATOM 4929 C C . PHE A 1 611 ? 62.936 33.900 48.994 1.00 31.71 ? 647 PHE A C 1 ATOM 4930 O O . PHE A 1 611 ? 62.500 34.112 50.122 1.00 31.33 ? 647 PHE A O 1 ATOM 4931 C CB . PHE A 1 611 ? 61.077 34.495 47.462 1.00 30.49 ? 647 PHE A CB 1 ATOM 4932 C CG . PHE A 1 611 ? 60.240 34.118 46.282 1.00 28.68 ? 647 PHE A CG 1 ATOM 4933 C CD1 . PHE A 1 611 ? 60.697 34.344 44.998 1.00 27.58 ? 647 PHE A CD1 1 ATOM 4934 C CD2 . PHE A 1 611 ? 59.016 33.506 46.458 1.00 27.51 ? 647 PHE A CD2 1 ATOM 4935 C CE1 . PHE A 1 611 ? 59.937 33.971 43.895 1.00 29.28 ? 647 PHE A CE1 1 ATOM 4936 C CE2 . PHE A 1 611 ? 58.256 33.130 45.375 1.00 28.61 ? 647 PHE A CE2 1 ATOM 4937 C CZ . PHE A 1 611 ? 58.723 33.366 44.084 1.00 26.73 ? 647 PHE A CZ 1 ATOM 4938 N N . LYS A 1 612 ? 64.192 34.127 48.635 1.00 28.64 ? 648 LYS A N 1 ATOM 4939 C CA . LYS A 1 612 ? 65.170 34.643 49.573 1.00 33.50 ? 648 LYS A CA 1 ATOM 4940 C C . LYS A 1 612 ? 64.964 36.139 49.809 1.00 29.83 ? 648 LYS A C 1 ATOM 4941 O O . LYS A 1 612 ? 65.084 36.612 50.929 1.00 29.93 ? 648 LYS A O 1 ATOM 4942 C CB . LYS A 1 612 ? 66.587 34.368 49.063 1.00 34.03 ? 648 LYS A CB 1 ATOM 4943 C CG . LYS A 1 612 ? 67.664 34.941 49.956 1.00 38.71 ? 648 LYS A CG 1 ATOM 4944 C CD . LYS A 1 612 ? 69.052 34.624 49.445 1.00 40.37 ? 648 LYS A CD 1 ATOM 4945 C CE . LYS A 1 612 ? 70.074 35.244 50.384 1.00 48.06 ? 648 LYS A CE 1 ATOM 4946 N NZ . LYS A 1 612 ? 71.452 34.993 49.911 1.00 56.23 ? 648 LYS A NZ 1 ATOM 4947 N N . CYS A 1 613 ? 64.625 36.876 48.753 1.00 30.27 ? 649 CYS A N 1 ATOM 4948 C CA . CYS A 1 613 ? 64.520 38.327 48.843 1.00 29.18 ? 649 CYS A CA 1 ATOM 4949 C C . CYS A 1 613 ? 63.640 38.895 47.728 1.00 31.04 ? 649 CYS A C 1 ATOM 4950 O O . CYS A 1 613 ? 63.324 38.197 46.757 1.00 25.90 ? 649 CYS A O 1 ATOM 4951 C CB . CYS A 1 613 ? 65.912 38.951 48.757 1.00 29.74 ? 649 CYS A CB 1 ATOM 4952 S SG . CYS A 1 613 ? 66.712 38.667 47.156 1.00 42.26 ? 649 CYS A SG 1 ATOM 4953 N N . GLY A 1 614 ? 63.266 40.165 47.858 1.00 22.98 ? 650 GLY A N 1 ATOM 4954 C CA . GLY A 1 614 ? 62.384 40.786 46.882 1.00 28.22 ? 650 GLY A CA 1 ATOM 4955 C C . GLY A 1 614 ? 62.331 42.296 46.980 1.00 27.09 ? 650 GLY A C 1 ATOM 4956 O O . GLY A 1 614 ? 62.663 42.881 48.020 1.00 25.39 ? 650 GLY A O 1 ATOM 4957 N N . ILE A 1 615 ? 61.906 42.926 45.890 1.00 24.85 ? 651 ILE A N 1 ATOM 4958 C CA . ILE A 1 615 ? 61.841 44.378 45.796 1.00 22.20 ? 651 ILE A CA 1 ATOM 4959 C C . ILE A 1 615 ? 60.441 44.772 45.324 1.00 27.51 ? 651 ILE A C 1 ATOM 4960 O O . ILE A 1 615 ? 59.963 44.267 44.311 1.00 25.76 ? 651 ILE A O 1 ATOM 4961 C CB . ILE A 1 615 ? 62.824 44.905 44.741 1.00 22.16 ? 651 ILE A CB 1 ATOM 4962 C CG1 . ILE A 1 615 ? 64.245 44.427 45.030 1.00 24.74 ? 651 ILE A CG1 1 ATOM 4963 C CG2 . ILE A 1 615 ? 62.757 46.419 44.690 1.00 19.99 ? 651 ILE A CG2 1 ATOM 4964 C CD1 . ILE A 1 615 ? 65.278 44.921 43.998 1.00 25.78 ? 651 ILE A CD1 1 ATOM 4965 N N . ALA A 1 616 ? 59.778 45.669 46.049 1.00 24.23 ? 652 ALA A N 1 ATOM 4966 C CA . ALA A 1 616 ? 58.491 46.167 45.608 1.00 21.23 ? 652 ALA A CA 1 ATOM 4967 C C . ALA A 1 616 ? 58.618 47.646 45.350 1.00 23.34 ? 652 ALA A C 1 ATOM 4968 O O . ALA A 1 616 ? 59.002 48.403 46.243 1.00 23.41 ? 652 ALA A O 1 ATOM 4969 C CB . ALA A 1 616 ? 57.417 45.896 46.663 1.00 22.91 ? 652 ALA A CB 1 ATOM 4970 N N . VAL A 1 617 ? 58.297 48.068 44.135 1.00 23.23 ? 653 VAL A N 1 ATOM 4971 C CA . VAL A 1 617 ? 58.358 49.486 43.797 1.00 22.21 ? 653 VAL A CA 1 ATOM 4972 C C . VAL A 1 617 ? 56.940 50.032 43.662 1.00 24.71 ? 653 VAL A C 1 ATOM 4973 O O . VAL A 1 617 ? 56.136 49.512 42.893 1.00 22.62 ? 653 VAL A O 1 ATOM 4974 C CB . VAL A 1 617 ? 59.116 49.722 42.455 1.00 24.74 ? 653 VAL A CB 1 ATOM 4975 C CG1 . VAL A 1 617 ? 59.178 51.223 42.120 1.00 21.97 ? 653 VAL A CG1 1 ATOM 4976 C CG2 . VAL A 1 617 ? 60.498 49.108 42.498 1.00 22.52 ? 653 VAL A CG2 1 ATOM 4977 N N . ALA A 1 618 ? 56.644 51.093 44.398 1.00 23.17 ? 654 ALA A N 1 ATOM 4978 C CA . ALA A 1 618 ? 55.330 51.728 44.351 1.00 23.79 ? 654 ALA A CA 1 ATOM 4979 C C . ALA A 1 618 ? 54.186 50.721 44.381 1.00 24.20 ? 654 ALA A C 1 ATOM 4980 O O . ALA A 1 618 ? 53.315 50.756 43.516 1.00 26.03 ? 654 ALA A O 1 ATOM 4981 C CB . ALA A 1 618 ? 55.220 52.650 43.103 1.00 20.84 ? 654 ALA A CB 1 ATOM 4982 N N . PRO A 1 619 ? 54.171 49.829 45.388 1.00 22.37 ? 655 PRO A N 1 ATOM 4983 C CA . PRO A 1 619 ? 53.138 48.802 45.440 1.00 22.14 ? 655 PRO A CA 1 ATOM 4984 C C . PRO A 1 619 ? 51.823 49.362 45.936 1.00 25.50 ? 655 PRO A C 1 ATOM 4985 O O . PRO A 1 619 ? 51.830 50.329 46.673 1.00 23.17 ? 655 PRO A O 1 ATOM 4986 C CB . PRO A 1 619 ? 53.670 47.832 46.494 1.00 23.62 ? 655 PRO A CB 1 ATOM 4987 C CG . PRO A 1 619 ? 54.419 48.718 47.461 1.00 24.02 ? 655 PRO A CG 1 ATOM 4988 C CD . PRO A 1 619 ? 55.070 49.772 46.557 1.00 21.34 ? 655 PRO A CD 1 ATOM 4989 N N . VAL A 1 620 ? 50.713 48.765 45.517 1.00 23.42 ? 656 VAL A N 1 ATOM 4990 C CA . VAL A 1 620 ? 49.476 48.912 46.241 1.00 23.95 ? 656 VAL A CA 1 ATOM 4991 C C . VAL A 1 620 ? 49.613 48.045 47.489 1.00 26.70 ? 656 VAL A C 1 ATOM 4992 O O . VAL A 1 620 ? 50.238 46.984 47.421 1.00 26.20 ? 656 VAL A O 1 ATOM 4993 C CB . VAL A 1 620 ? 48.307 48.395 45.403 1.00 25.92 ? 656 VAL A CB 1 ATOM 4994 C CG1 . VAL A 1 620 ? 47.143 48.015 46.325 1.00 25.62 ? 656 VAL A CG1 1 ATOM 4995 C CG2 . VAL A 1 620 ? 47.902 49.447 44.391 1.00 22.89 ? 656 VAL A CG2 1 ATOM 4996 N N . SER A 1 621 ? 49.059 48.483 48.622 1.00 23.46 ? 657 SER A N 1 ATOM 4997 C CA . SER A 1 621 ? 49.098 47.676 49.843 1.00 26.65 ? 657 SER A CA 1 ATOM 4998 C C . SER A 1 621 ? 47.716 47.260 50.357 1.00 28.81 ? 657 SER A C 1 ATOM 4999 O O . SER A 1 621 ? 47.591 46.273 51.082 1.00 28.20 ? 657 SER A O 1 ATOM 5000 C CB . SER A 1 621 ? 49.854 48.400 50.961 1.00 25.01 ? 657 SER A CB 1 ATOM 5001 O OG . SER A 1 621 ? 49.141 49.558 51.360 1.00 24.60 ? 657 SER A OG 1 ATOM 5002 N N . ARG A 1 622 ? 46.686 48.026 50.025 1.00 24.56 ? 658 ARG A N 1 ATOM 5003 C CA . ARG A 1 622 ? 45.324 47.555 50.260 1.00 25.64 ? 658 ARG A CA 1 ATOM 5004 C C . ARG A 1 622 ? 44.367 48.248 49.309 1.00 26.00 ? 658 ARG A C 1 ATOM 5005 O O . ARG A 1 622 ? 44.531 49.428 48.989 1.00 23.88 ? 658 ARG A O 1 ATOM 5006 C CB . ARG A 1 622 ? 44.901 47.723 51.719 1.00 35.64 ? 658 ARG A CB 1 ATOM 5007 C CG . ARG A 1 622 ? 44.542 49.120 52.119 1.00 32.32 ? 658 ARG A CG 1 ATOM 5008 C CD . ARG A 1 622 ? 44.286 49.208 53.633 1.00 39.81 ? 658 ARG A CD 1 ATOM 5009 N NE . ARG A 1 622 ? 43.199 48.339 54.069 1.00 43.71 ? 658 ARG A NE 1 ATOM 5010 C CZ . ARG A 1 622 ? 42.054 48.774 54.587 1.00 45.62 ? 658 ARG A CZ 1 ATOM 5011 N NH1 . ARG A 1 622 ? 41.834 50.077 54.738 1.00 43.58 ? 658 ARG A NH1 1 ATOM 5012 N NH2 . ARG A 1 622 ? 41.125 47.902 54.958 1.00 47.94 ? 658 ARG A NH2 1 ATOM 5013 N N . TRP A 1 623 ? 43.373 47.513 48.834 1.00 26.82 ? 659 TRP A N 1 ATOM 5014 C CA . TRP A 1 623 ? 42.600 48.003 47.701 1.00 24.84 ? 659 TRP A CA 1 ATOM 5015 C C . TRP A 1 623 ? 41.739 49.241 47.979 1.00 26.88 ? 659 TRP A C 1 ATOM 5016 O O . TRP A 1 623 ? 41.423 49.995 47.064 1.00 24.34 ? 659 TRP A O 1 ATOM 5017 C CB . TRP A 1 623 ? 41.847 46.859 47.020 1.00 27.22 ? 659 TRP A CB 1 ATOM 5018 C CG . TRP A 1 623 ? 42.829 45.991 46.304 1.00 25.31 ? 659 TRP A CG 1 ATOM 5019 C CD1 . TRP A 1 623 ? 43.258 44.746 46.679 1.00 25.71 ? 659 TRP A CD1 1 ATOM 5020 C CD2 . TRP A 1 623 ? 43.590 46.347 45.143 1.00 22.84 ? 659 TRP A CD2 1 ATOM 5021 N NE1 . TRP A 1 623 ? 44.211 44.289 45.792 1.00 27.85 ? 659 TRP A NE1 1 ATOM 5022 C CE2 . TRP A 1 623 ? 44.432 45.255 44.841 1.00 24.05 ? 659 TRP A CE2 1 ATOM 5023 C CE3 . TRP A 1 623 ? 43.621 47.472 44.317 1.00 24.51 ? 659 TRP A CE3 1 ATOM 5024 C CZ2 . TRP A 1 623 ? 45.304 45.260 43.756 1.00 23.36 ? 659 TRP A CZ2 1 ATOM 5025 C CZ3 . TRP A 1 623 ? 44.486 47.472 43.220 1.00 25.02 ? 659 TRP A CZ3 1 ATOM 5026 C CH2 . TRP A 1 623 ? 45.314 46.372 42.954 1.00 24.08 ? 659 TRP A CH2 1 ATOM 5027 N N . GLU A 1 624 ? 41.415 49.493 49.241 1.00 25.05 ? 660 GLU A N 1 ATOM 5028 C CA . GLU A 1 624 ? 40.691 50.717 49.560 1.00 25.51 ? 660 GLU A CA 1 ATOM 5029 C C . GLU A 1 624 ? 41.487 51.988 49.270 1.00 26.57 ? 660 GLU A C 1 ATOM 5030 O O . GLU A 1 624 ? 40.905 53.071 49.201 1.00 25.49 ? 660 GLU A O 1 ATOM 5031 C CB . GLU A 1 624 ? 40.238 50.732 51.024 1.00 30.78 ? 660 GLU A CB 1 ATOM 5032 C CG . GLU A 1 624 ? 39.196 49.698 51.342 1.00 34.24 ? 660 GLU A CG 1 ATOM 5033 C CD . GLU A 1 624 ? 39.796 48.450 51.990 1.00 40.03 ? 660 GLU A CD 1 ATOM 5034 O OE1 . GLU A 1 624 ? 40.859 47.956 51.524 1.00 36.57 ? 660 GLU A OE1 1 ATOM 5035 O OE2 . GLU A 1 624 ? 39.194 47.958 52.966 1.00 41.14 ? 660 GLU A OE2 1 ATOM 5036 N N . TYR A 1 625 ? 42.808 51.872 49.131 1.00 22.39 ? 661 TYR A N 1 ATOM 5037 C CA . TYR A 1 625 ? 43.635 53.047 48.836 1.00 23.49 ? 661 TYR A CA 1 ATOM 5038 C C . TYR A 1 625 ? 43.731 53.376 47.340 1.00 25.08 ? 661 TYR A C 1 ATOM 5039 O O . TYR A 1 625 ? 44.162 54.481 46.971 1.00 22.48 ? 661 TYR A O 1 ATOM 5040 C CB . TYR A 1 625 ? 45.064 52.860 49.339 1.00 24.74 ? 661 TYR A CB 1 ATOM 5041 C CG . TYR A 1 625 ? 45.214 52.629 50.816 1.00 28.14 ? 661 TYR A CG 1 ATOM 5042 C CD1 . TYR A 1 625 ? 44.263 53.086 51.726 1.00 26.19 ? 661 TYR A CD1 1 ATOM 5043 C CD2 . TYR A 1 625 ? 46.329 51.959 51.310 1.00 28.92 ? 661 TYR A CD2 1 ATOM 5044 C CE1 . TYR A 1 625 ? 44.427 52.862 53.086 1.00 29.70 ? 661 TYR A CE1 1 ATOM 5045 C CE2 . TYR A 1 625 ? 46.497 51.743 52.658 1.00 27.25 ? 661 TYR A CE2 1 ATOM 5046 C CZ . TYR A 1 625 ? 45.547 52.186 53.537 1.00 28.28 ? 661 TYR A CZ 1 ATOM 5047 O OH . TYR A 1 625 ? 45.738 51.946 54.887 1.00 30.91 ? 661 TYR A OH 1 ATOM 5048 N N . TYR A 1 626 ? 43.396 52.416 46.478 1.00 24.70 ? 662 TYR A N 1 ATOM 5049 C CA . TYR A 1 626 ? 43.559 52.636 45.035 1.00 21.91 ? 662 TYR A CA 1 ATOM 5050 C C . TYR A 1 626 ? 42.285 53.231 44.407 1.00 25.66 ? 662 TYR A C 1 ATOM 5051 O O . TYR A 1 626 ? 41.268 53.358 45.095 1.00 27.73 ? 662 TYR A O 1 ATOM 5052 C CB . TYR A 1 626 ? 44.070 51.389 44.300 1.00 21.97 ? 662 TYR A CB 1 ATOM 5053 C CG . TYR A 1 626 ? 44.683 51.788 42.966 1.00 26.17 ? 662 TYR A CG 1 ATOM 5054 C CD1 . TYR A 1 626 ? 45.677 52.761 42.909 1.00 22.48 ? 662 TYR A CD1 1 ATOM 5055 C CD2 . TYR A 1 626 ? 44.239 51.236 41.772 1.00 24.38 ? 662 TYR A CD2 1 ATOM 5056 C CE1 . TYR A 1 626 ? 46.217 53.181 41.701 1.00 24.05 ? 662 TYR A CE1 1 ATOM 5057 C CE2 . TYR A 1 626 ? 44.790 51.632 40.548 1.00 27.27 ? 662 TYR A CE2 1 ATOM 5058 C CZ . TYR A 1 626 ? 45.776 52.603 40.523 1.00 26.73 ? 662 TYR A CZ 1 ATOM 5059 O OH . TYR A 1 626 ? 46.312 53.005 39.321 1.00 25.77 ? 662 TYR A OH 1 ATOM 5060 N N . ASP A 1 627 ? 42.329 53.646 43.142 1.00 24.57 ? 663 ASP A N 1 ATOM 5061 C CA . ASP A 1 627 ? 41.183 54.383 42.584 1.00 24.40 ? 663 ASP A CA 1 ATOM 5062 C C . ASP A 1 627 ? 39.933 53.522 42.330 1.00 26.40 ? 663 ASP A C 1 ATOM 5063 O O . ASP A 1 627 ? 40.012 52.293 42.183 1.00 25.90 ? 663 ASP A O 1 ATOM 5064 C CB . ASP A 1 627 ? 41.568 55.231 41.360 1.00 24.45 ? 663 ASP A CB 1 ATOM 5065 C CG . ASP A 1 627 ? 41.757 54.406 40.075 1.00 28.11 ? 663 ASP A CG 1 ATOM 5066 O OD1 . ASP A 1 627 ? 40.810 53.721 39.621 1.00 26.49 ? 663 ASP A OD1 1 ATOM 5067 O OD2 . ASP A 1 627 ? 42.863 54.476 39.493 1.00 28.13 ? 663 ASP A OD2 1 ATOM 5068 N N . SER A 1 628 ? 38.777 54.174 42.304 1.00 25.03 ? 664 SER A N 1 ATOM 5069 C CA . SER A 1 628 ? 37.497 53.463 42.244 1.00 22.87 ? 664 SER A CA 1 ATOM 5070 C C . SER A 1 628 ? 37.314 52.692 40.946 1.00 26.92 ? 664 SER A C 1 ATOM 5071 O O . SER A 1 628 ? 36.964 51.513 40.973 1.00 27.01 ? 664 SER A O 1 ATOM 5072 C CB . SER A 1 628 ? 36.342 54.444 42.412 1.00 25.59 ? 664 SER A CB 1 ATOM 5073 O OG . SER A 1 628 ? 36.434 55.469 41.432 1.00 26.78 ? 664 SER A OG 1 ATOM 5074 N N . VAL A 1 629 ? 37.558 53.351 39.814 1.00 23.47 ? 665 VAL A N 1 ATOM 5075 C CA . VAL A 1 629 ? 37.279 52.749 38.514 1.00 22.66 ? 665 VAL A CA 1 ATOM 5076 C C . VAL A 1 629 ? 38.051 51.467 38.279 1.00 26.81 ? 665 VAL A C 1 ATOM 5077 O O . VAL A 1 629 ? 37.496 50.487 37.804 1.00 30.19 ? 665 VAL A O 1 ATOM 5078 C CB . VAL A 1 629 ? 37.586 53.702 37.366 1.00 24.26 ? 665 VAL A CB 1 ATOM 5079 C CG1 . VAL A 1 629 ? 37.305 53.013 36.035 1.00 28.70 ? 665 VAL A CG1 1 ATOM 5080 C CG2 . VAL A 1 629 ? 36.757 54.963 37.517 1.00 26.40 ? 665 VAL A CG2 1 ATOM 5081 N N . TYR A 1 630 ? 39.341 51.468 38.592 1.00 25.33 ? 666 TYR A N 1 ATOM 5082 C CA . TYR A 1 630 ? 40.142 50.268 38.386 1.00 27.37 ? 666 TYR A CA 1 ATOM 5083 C C . TYR A 1 630 ? 39.806 49.215 39.451 1.00 27.56 ? 666 TYR A C 1 ATOM 5084 O O . TYR A 1 630 ? 39.565 48.042 39.150 1.00 28.05 ? 666 TYR A O 1 ATOM 5085 C CB . TYR A 1 630 ? 41.631 50.609 38.450 1.00 25.63 ? 666 TYR A CB 1 ATOM 5086 C CG . TYR A 1 630 ? 42.541 49.423 38.251 1.00 28.30 ? 666 TYR A CG 1 ATOM 5087 C CD1 . TYR A 1 630 ? 42.871 48.594 39.311 1.00 26.07 ? 666 TYR A CD1 1 ATOM 5088 C CD2 . TYR A 1 630 ? 43.071 49.135 36.999 1.00 25.45 ? 666 TYR A CD2 1 ATOM 5089 C CE1 . TYR A 1 630 ? 43.710 47.515 39.138 1.00 25.06 ? 666 TYR A CE1 1 ATOM 5090 C CE2 . TYR A 1 630 ? 43.900 48.068 36.818 1.00 26.88 ? 666 TYR A CE2 1 ATOM 5091 C CZ . TYR A 1 630 ? 44.220 47.256 37.886 1.00 30.34 ? 666 TYR A CZ 1 ATOM 5092 O OH . TYR A 1 630 ? 45.053 46.170 37.691 1.00 27.38 ? 666 TYR A OH 1 ATOM 5093 N N . THR A 1 631 ? 39.798 49.645 40.701 1.00 26.26 ? 667 THR A N 1 ATOM 5094 C CA . THR A 1 631 ? 39.668 48.712 41.801 1.00 27.64 ? 667 THR A CA 1 ATOM 5095 C C . THR A 1 631 ? 38.309 48.031 41.795 1.00 27.70 ? 667 THR A C 1 ATOM 5096 O O . THR A 1 631 ? 38.225 46.814 41.915 1.00 30.86 ? 667 THR A O 1 ATOM 5097 C CB . THR A 1 631 ? 39.846 49.419 43.149 1.00 28.05 ? 667 THR A CB 1 ATOM 5098 O OG1 . THR A 1 631 ? 41.078 50.158 43.141 1.00 25.10 ? 667 THR A OG1 1 ATOM 5099 C CG2 . THR A 1 631 ? 39.842 48.394 44.288 1.00 25.00 ? 667 THR A CG2 1 ATOM 5100 N N . GLU A 1 632 ? 37.243 48.816 41.677 1.00 26.10 ? 668 GLU A N 1 ATOM 5101 C CA . GLU A 1 632 ? 35.903 48.257 41.771 1.00 24.39 ? 668 GLU A CA 1 ATOM 5102 C C . GLU A 1 632 ? 35.582 47.389 40.562 1.00 29.45 ? 668 GLU A C 1 ATOM 5103 O O . GLU A 1 632 ? 34.705 46.536 40.616 1.00 25.70 ? 668 GLU A O 1 ATOM 5104 C CB . GLU A 1 632 ? 34.880 49.368 41.915 1.00 25.79 ? 668 GLU A CB 1 ATOM 5105 C CG . GLU A 1 632 ? 35.077 50.185 43.173 1.00 27.15 ? 668 GLU A CG 1 ATOM 5106 C CD . GLU A 1 632 ? 34.305 51.467 43.135 1.00 30.84 ? 668 GLU A CD 1 ATOM 5107 O OE1 . GLU A 1 632 ? 33.421 51.593 42.256 1.00 31.67 ? 668 GLU A OE1 1 ATOM 5108 O OE2 . GLU A 1 632 ? 34.594 52.353 43.969 1.00 27.42 ? 668 GLU A OE2 1 ATOM 5109 N N . ARG A 1 633 ? 36.309 47.600 39.473 1.00 26.99 ? 669 ARG A N 1 ATOM 5110 C CA . ARG A 1 633 ? 36.136 46.764 38.296 1.00 28.39 ? 669 ARG A CA 1 ATOM 5111 C C . ARG A 1 633 ? 36.340 45.296 38.654 1.00 28.44 ? 669 ARG A C 1 ATOM 5112 O O . ARG A 1 633 ? 35.579 44.432 38.210 1.00 25.96 ? 669 ARG A O 1 ATOM 5113 C CB . ARG A 1 633 ? 37.109 47.187 37.201 1.00 23.83 ? 669 ARG A CB 1 ATOM 5114 C CG . ARG A 1 633 ? 36.913 46.453 35.877 1.00 29.51 ? 669 ARG A CG 1 ATOM 5115 C CD . ARG A 1 633 ? 37.225 47.400 34.734 1.00 30.60 ? 669 ARG A CD 1 ATOM 5116 N NE . ARG A 1 633 ? 38.647 47.538 34.596 1.00 30.64 ? 669 ARG A NE 1 ATOM 5117 C CZ . ARG A 1 633 ? 39.296 48.668 34.340 1.00 31.84 ? 669 ARG A CZ 1 ATOM 5118 N NH1 . ARG A 1 633 ? 38.654 49.821 34.182 1.00 25.94 ? 669 ARG A NH1 1 ATOM 5119 N NH2 . ARG A 1 633 ? 40.613 48.620 34.240 1.00 25.69 ? 669 ARG A NH2 1 ATOM 5120 N N . TYR A 1 634 ? 37.358 45.021 39.467 1.00 24.86 ? 670 TYR A N 1 ATOM 5121 C CA . TYR A 1 634 ? 37.693 43.650 39.859 1.00 24.40 ? 670 TYR A CA 1 ATOM 5122 C C . TYR A 1 634 ? 37.176 43.284 41.240 1.00 30.23 ? 670 TYR A C 1 ATOM 5123 O O . TYR A 1 634 ? 37.000 42.103 41.546 1.00 30.32 ? 670 TYR A O 1 ATOM 5124 C CB . TYR A 1 634 ? 39.213 43.430 39.817 1.00 23.45 ? 670 TYR A CB 1 ATOM 5125 C CG . TYR A 1 634 ? 39.824 44.015 38.567 1.00 26.59 ? 670 TYR A CG 1 ATOM 5126 C CD1 . TYR A 1 634 ? 39.623 43.415 37.324 1.00 28.54 ? 670 TYR A CD1 1 ATOM 5127 C CD2 . TYR A 1 634 ? 40.551 45.198 38.618 1.00 27.79 ? 670 TYR A CD2 1 ATOM 5128 C CE1 . TYR A 1 634 ? 40.159 43.967 36.161 1.00 26.11 ? 670 TYR A CE1 1 ATOM 5129 C CE2 . TYR A 1 634 ? 41.088 45.753 37.477 1.00 26.09 ? 670 TYR A CE2 1 ATOM 5130 C CZ . TYR A 1 634 ? 40.883 45.138 36.254 1.00 27.21 ? 670 TYR A CZ 1 ATOM 5131 O OH . TYR A 1 634 ? 41.415 45.706 35.132 1.00 24.72 ? 670 TYR A OH 1 ATOM 5132 N N . MET A 1 635 ? 36.942 44.286 42.081 1.00 27.41 ? 671 MET A N 1 ATOM 5133 C CA . MET A 1 635 ? 36.712 44.009 43.497 1.00 26.53 ? 671 MET A CA 1 ATOM 5134 C C . MET A 1 635 ? 35.303 44.318 44.022 1.00 27.46 ? 671 MET A C 1 ATOM 5135 O O . MET A 1 635 ? 34.992 43.991 45.156 1.00 32.34 ? 671 MET A O 1 ATOM 5136 C CB . MET A 1 635 ? 37.760 44.744 44.340 1.00 28.74 ? 671 MET A CB 1 ATOM 5137 C CG . MET A 1 635 ? 39.153 44.126 44.281 1.00 28.19 ? 671 MET A CG 1 ATOM 5138 S SD . MET A 1 635 ? 39.254 42.578 45.198 1.00 31.57 ? 671 MET A SD 1 ATOM 5139 C CE . MET A 1 635 ? 39.350 43.179 46.891 1.00 33.69 ? 671 MET A CE 1 ATOM 5140 N N . GLY A 1 636 ? 34.456 44.937 43.208 1.00 31.99 ? 672 GLY A N 1 ATOM 5141 C CA . GLY A 1 636 ? 33.150 45.369 43.673 1.00 28.30 ? 672 GLY A CA 1 ATOM 5142 C C . GLY A 1 636 ? 33.372 46.498 44.655 1.00 33.77 ? 672 GLY A C 1 ATOM 5143 O O . GLY A 1 636 ? 34.440 47.112 44.668 1.00 29.40 ? 672 GLY A O 1 ATOM 5144 N N . LEU A 1 637 ? 32.373 46.778 45.482 1.00 36.50 ? 673 LEU A N 1 ATOM 5145 C CA . LEU A 1 637 ? 32.498 47.816 46.497 1.00 32.46 ? 673 LEU A CA 1 ATOM 5146 C C . LEU A 1 637 ? 32.935 47.232 47.845 1.00 35.42 ? 673 LEU A C 1 ATOM 5147 O O . LEU A 1 637 ? 32.643 46.075 48.164 1.00 34.52 ? 673 LEU A O 1 ATOM 5148 C CB . LEU A 1 637 ? 31.182 48.584 46.629 1.00 34.21 ? 673 LEU A CB 1 ATOM 5149 C CG . LEU A 1 637 ? 30.677 49.217 45.330 1.00 38.35 ? 673 LEU A CG 1 ATOM 5150 C CD1 . LEU A 1 637 ? 29.209 49.617 45.450 1.00 43.64 ? 673 LEU A CD1 1 ATOM 5151 C CD2 . LEU A 1 637 ? 31.537 50.414 44.943 1.00 32.61 ? 673 LEU A CD2 1 ATOM 5152 N N . PRO A 1 638 ? 33.667 48.029 48.629 1.00 32.67 ? 674 PRO A N 1 ATOM 5153 C CA . PRO A 1 638 ? 34.153 47.607 49.944 1.00 34.14 ? 674 PRO A CA 1 ATOM 5154 C C . PRO A 1 638 ? 33.086 47.823 51.030 1.00 34.88 ? 674 PRO A C 1 ATOM 5155 O O . PRO A 1 638 ? 33.337 48.541 51.988 1.00 36.71 ? 674 PRO A O 1 ATOM 5156 C CB . PRO A 1 638 ? 35.340 48.551 50.177 1.00 32.58 ? 674 PRO A CB 1 ATOM 5157 C CG . PRO A 1 638 ? 34.919 49.818 49.508 1.00 31.19 ? 674 PRO A CG 1 ATOM 5158 C CD . PRO A 1 638 ? 34.145 49.378 48.268 1.00 31.00 ? 674 PRO A CD 1 ATOM 5159 N N . THR A 1 639 ? 31.911 47.228 50.860 1.00 34.91 ? 675 THR A N 1 ATOM 5160 C CA . THR A 1 639 ? 30.830 47.340 51.836 1.00 38.59 ? 675 THR A CA 1 ATOM 5161 C C . THR A 1 639 ? 30.453 45.950 52.315 1.00 36.58 ? 675 THR A C 1 ATOM 5162 O O . THR A 1 639 ? 30.656 44.967 51.593 1.00 40.23 ? 675 THR A O 1 ATOM 5163 C CB . THR A 1 639 ? 29.570 48.010 51.246 1.00 39.21 ? 675 THR A CB 1 ATOM 5164 O OG1 . THR A 1 639 ? 29.033 47.194 50.197 1.00 38.50 ? 675 THR A OG1 1 ATOM 5165 C CG2 . THR A 1 639 ? 29.883 49.406 50.704 1.00 43.07 ? 675 THR A CG2 1 ATOM 5166 N N . PRO A 1 640 ? 29.891 45.856 53.532 1.00 42.92 ? 676 PRO A N 1 ATOM 5167 C CA . PRO A 1 640 ? 29.546 44.558 54.135 1.00 39.36 ? 676 PRO A CA 1 ATOM 5168 C C . PRO A 1 640 ? 28.594 43.732 53.264 1.00 40.39 ? 676 PRO A C 1 ATOM 5169 O O . PRO A 1 640 ? 28.686 42.500 53.253 1.00 42.77 ? 676 PRO A O 1 ATOM 5170 C CB . PRO A 1 640 ? 28.871 44.958 55.451 1.00 43.69 ? 676 PRO A CB 1 ATOM 5171 C CG . PRO A 1 640 ? 29.473 46.297 55.785 1.00 45.08 ? 676 PRO A CG 1 ATOM 5172 C CD . PRO A 1 640 ? 29.669 46.982 54.461 1.00 41.52 ? 676 PRO A CD 1 ATOM 5173 N N . GLU A 1 641 ? 27.707 44.409 52.539 1.00 40.48 ? 677 GLU A N 1 ATOM 5174 C CA . GLU A 1 641 ? 26.790 43.753 51.600 1.00 46.86 ? 677 GLU A CA 1 ATOM 5175 C C . GLU A 1 641 ? 27.453 43.322 50.278 1.00 45.83 ? 677 GLU A C 1 ATOM 5176 O O . GLU A 1 641 ? 26.936 42.440 49.585 1.00 47.50 ? 677 GLU A O 1 ATOM 5177 C CB . GLU A 1 641 ? 25.592 44.662 51.300 1.00 44.03 ? 677 GLU A CB 1 ATOM 5178 C CG . GLU A 1 641 ? 25.327 45.694 52.389 1.00 54.52 ? 677 GLU A CG 1 ATOM 5179 C CD . GLU A 1 641 ? 26.021 47.019 52.109 1.00 55.44 ? 677 GLU A CD 1 ATOM 5180 O OE1 . GLU A 1 641 ? 26.397 47.731 53.072 1.00 56.40 ? 677 GLU A OE1 1 ATOM 5181 O OE2 . GLU A 1 641 ? 26.179 47.349 50.911 1.00 63.22 ? 677 GLU A OE2 1 ATOM 5182 N N . ASP A 1 642 ? 28.577 43.942 49.914 1.00 40.97 ? 678 ASP A N 1 ATOM 5183 C CA . ASP A 1 642 ? 29.275 43.535 48.688 1.00 40.16 ? 678 ASP A CA 1 ATOM 5184 C C . ASP A 1 642 ? 30.545 42.723 48.991 1.00 40.89 ? 678 ASP A C 1 ATOM 5185 O O . ASP A 1 642 ? 30.460 41.527 49.296 1.00 42.27 ? 678 ASP A O 1 ATOM 5186 C CB . ASP A 1 642 ? 29.546 44.726 47.746 1.00 36.14 ? 678 ASP A CB 1 ATOM 5187 C CG . ASP A 1 642 ? 29.964 44.287 46.319 1.00 38.28 ? 678 ASP A CG 1 ATOM 5188 O OD1 . ASP A 1 642 ? 30.382 43.129 46.131 1.00 39.07 ? 678 ASP A OD1 1 ATOM 5189 O OD2 . ASP A 1 642 ? 29.884 45.107 45.375 1.00 37.17 ? 678 ASP A OD2 1 ATOM 5190 N N . ASN A 1 643 ? 31.716 43.351 48.923 1.00 35.43 ? 679 ASN A N 1 ATOM 5191 C CA . ASN A 1 643 ? 32.951 42.574 48.983 1.00 34.42 ? 679 ASN A CA 1 ATOM 5192 C C . ASN A 1 643 ? 33.938 42.996 50.067 1.00 33.51 ? 679 ASN A C 1 ATOM 5193 O O . ASN A 1 643 ? 35.113 42.659 49.984 1.00 33.80 ? 679 ASN A O 1 ATOM 5194 C CB . ASN A 1 643 ? 33.637 42.603 47.610 1.00 34.27 ? 679 ASN A CB 1 ATOM 5195 C CG . ASN A 1 643 ? 34.586 41.435 47.397 1.00 36.28 ? 679 ASN A CG 1 ATOM 5196 O OD1 . ASN A 1 643 ? 34.434 40.370 47.998 1.00 32.07 ? 679 ASN A OD1 1 ATOM 5197 N ND2 . ASN A 1 643 ? 35.562 41.627 46.514 1.00 33.03 ? 679 ASN A ND2 1 ATOM 5198 N N . LEU A 1 644 ? 33.469 43.717 51.087 1.00 34.85 ? 680 LEU A N 1 ATOM 5199 C CA . LEU A 1 644 ? 34.347 44.197 52.164 1.00 32.73 ? 680 LEU A CA 1 ATOM 5200 C C . LEU A 1 644 ? 35.237 43.120 52.798 1.00 36.93 ? 680 LEU A C 1 ATOM 5201 O O . LEU A 1 644 ? 36.405 43.377 53.104 1.00 37.97 ? 680 LEU A O 1 ATOM 5202 C CB . LEU A 1 644 ? 33.552 44.917 53.263 1.00 34.83 ? 680 LEU A CB 1 ATOM 5203 C CG . LEU A 1 644 ? 34.385 45.413 54.451 1.00 39.14 ? 680 LEU A CG 1 ATOM 5204 C CD1 . LEU A 1 644 ? 35.565 46.239 53.978 1.00 35.96 ? 680 LEU A CD1 1 ATOM 5205 C CD2 . LEU A 1 644 ? 33.527 46.219 55.430 1.00 39.23 ? 680 LEU A CD2 1 ATOM 5206 N N . ASP A 1 645 ? 34.708 41.920 52.994 1.00 33.28 ? 681 ASP A N 1 ATOM 5207 C CA . ASP A 1 645 ? 35.522 40.866 53.588 1.00 36.95 ? 681 ASP A CA 1 ATOM 5208 C C . ASP A 1 645 ? 36.792 40.575 52.786 1.00 37.54 ? 681 ASP A C 1 ATOM 5209 O O . ASP A 1 645 ? 37.869 40.422 53.363 1.00 33.52 ? 681 ASP A O 1 ATOM 5210 C CB . ASP A 1 645 ? 34.710 39.587 53.814 1.00 38.50 ? 681 ASP A CB 1 ATOM 5211 C CG . ASP A 1 645 ? 33.679 39.740 54.936 1.00 50.66 ? 681 ASP A CG 1 ATOM 5212 O OD1 . ASP A 1 645 ? 33.849 40.649 55.785 1.00 44.74 ? 681 ASP A OD1 1 ATOM 5213 O OD2 . ASP A 1 645 ? 32.698 38.958 54.966 1.00 54.91 ? 681 ASP A OD2 1 ATOM 5214 N N . HIS A 1 646 ? 36.694 40.497 51.465 1.00 34.10 ? 682 HIS A N 1 ATOM 5215 C CA . HIS A 1 646 ? 37.923 40.254 50.707 1.00 34.99 ? 682 HIS A CA 1 ATOM 5216 C C . HIS A 1 646 ? 38.839 41.486 50.538 1.00 31.00 ? 682 HIS A C 1 ATOM 5217 O O . HIS A 1 646 ? 40.053 41.343 50.441 1.00 34.70 ? 682 HIS A O 1 ATOM 5218 C CB . HIS A 1 646 ? 37.699 39.564 49.371 1.00 34.28 ? 682 HIS A CB 1 ATOM 5219 C CG . HIS A 1 646 ? 38.987 39.214 48.689 1.00 38.78 ? 682 HIS A CG 1 ATOM 5220 N ND1 . HIS A 1 646 ? 39.775 38.151 49.086 1.00 38.92 ? 682 HIS A ND1 1 ATOM 5221 C CD2 . HIS A 1 646 ? 39.661 39.827 47.686 1.00 36.29 ? 682 HIS A CD2 1 ATOM 5222 C CE1 . HIS A 1 646 ? 40.863 38.109 48.335 1.00 38.95 ? 682 HIS A CE1 1 ATOM 5223 N NE2 . HIS A 1 646 ? 40.817 39.112 47.477 1.00 34.36 ? 682 HIS A NE2 1 ATOM 5224 N N . TYR A 1 647 ? 38.274 42.684 50.519 1.00 27.51 ? 683 TYR A N 1 ATOM 5225 C CA . TYR A 1 647 ? 39.094 43.885 50.635 1.00 29.70 ? 683 TYR A CA 1 ATOM 5226 C C . TYR A 1 647 ? 39.990 43.797 51.884 1.00 32.96 ? 683 TYR A C 1 ATOM 5227 O O . TYR A 1 647 ? 41.167 44.171 51.843 1.00 30.04 ? 683 TYR A O 1 ATOM 5228 C CB . TYR A 1 647 ? 38.220 45.126 50.746 1.00 28.21 ? 683 TYR A CB 1 ATOM 5229 C CG . TYR A 1 647 ? 37.852 45.816 49.454 1.00 30.63 ? 683 TYR A CG 1 ATOM 5230 C CD1 . TYR A 1 647 ? 36.673 45.509 48.786 1.00 30.77 ? 683 TYR A CD1 1 ATOM 5231 C CD2 . TYR A 1 647 ? 38.671 46.804 48.915 1.00 30.98 ? 683 TYR A CD2 1 ATOM 5232 C CE1 . TYR A 1 647 ? 36.318 46.165 47.606 1.00 29.76 ? 683 TYR A CE1 1 ATOM 5233 C CE2 . TYR A 1 647 ? 38.330 47.464 47.735 1.00 27.38 ? 683 TYR A CE2 1 ATOM 5234 C CZ . TYR A 1 647 ? 37.158 47.142 47.086 1.00 33.27 ? 683 TYR A CZ 1 ATOM 5235 O OH . TYR A 1 647 ? 36.827 47.802 45.919 1.00 30.16 ? 683 TYR A OH 1 ATOM 5236 N N . ARG A 1 648 ? 39.433 43.318 52.998 1.00 32.47 ? 684 ARG A N 1 ATOM 5237 C CA . ARG A 1 648 ? 40.159 43.281 54.282 1.00 30.62 ? 684 ARG A CA 1 ATOM 5238 C C . ARG A 1 648 ? 41.149 42.125 54.396 1.00 30.37 ? 684 ARG A C 1 ATOM 5239 O O . ARG A 1 648 ? 42.118 42.208 55.136 1.00 32.50 ? 684 ARG A O 1 ATOM 5240 C CB . ARG A 1 648 ? 39.171 43.198 55.453 1.00 37.17 ? 684 ARG A CB 1 ATOM 5241 C CG . ARG A 1 648 ? 38.318 44.432 55.626 1.00 38.29 ? 684 ARG A CG 1 ATOM 5242 C CD . ARG A 1 648 ? 39.147 45.602 56.126 1.00 46.08 ? 684 ARG A CD 1 ATOM 5243 N NE . ARG A 1 648 ? 38.366 46.836 56.190 1.00 53.03 ? 684 ARG A NE 1 ATOM 5244 C CZ . ARG A 1 648 ? 37.353 47.040 57.032 1.00 55.28 ? 684 ARG A CZ 1 ATOM 5245 N NH1 . ARG A 1 648 ? 36.977 46.087 57.886 1.00 53.17 ? 684 ARG A NH1 1 ATOM 5246 N NH2 . ARG A 1 648 ? 36.706 48.200 57.011 1.00 56.90 ? 684 ARG A NH2 1 ATOM 5247 N N . ASN A 1 649 ? 40.891 41.046 53.662 1.00 33.42 ? 685 ASN A N 1 ATOM 5248 C CA . ASN A 1 649 ? 41.705 39.833 53.707 1.00 31.60 ? 685 ASN A CA 1 ATOM 5249 C C . ASN A 1 649 ? 42.847 39.856 52.685 1.00 33.85 ? 685 ASN A C 1 ATOM 5250 O O . ASN A 1 649 ? 43.614 38.912 52.592 1.00 38.19 ? 685 ASN A O 1 ATOM 5251 C CB . ASN A 1 649 ? 40.811 38.601 53.446 1.00 40.51 ? 685 ASN A CB 1 ATOM 5252 C CG . ASN A 1 649 ? 41.521 37.279 53.720 1.00 46.75 ? 685 ASN A CG 1 ATOM 5253 O OD1 . ASN A 1 649 ? 42.542 37.253 54.396 1.00 51.87 ? 685 ASN A OD1 1 ATOM 5254 N ND2 . ASN A 1 649 ? 40.975 36.174 53.203 1.00 50.88 ? 685 ASN A ND2 1 ATOM 5255 N N . SER A 1 650 ? 42.965 40.939 51.925 1.00 32.60 ? 686 SER A N 1 ATOM 5256 C CA . SER A 1 650 ? 43.877 40.956 50.787 1.00 29.78 ? 686 SER A CA 1 ATOM 5257 C C . SER A 1 650 ? 44.876 42.092 50.879 1.00 29.52 ? 686 SER A C 1 ATOM 5258 O O . SER A 1 650 ? 45.370 42.586 49.851 1.00 26.73 ? 686 SER A O 1 ATOM 5259 C CB . SER A 1 650 ? 43.081 41.085 49.486 1.00 29.99 ? 686 SER A CB 1 ATOM 5260 O OG . SER A 1 650 ? 42.478 42.370 49.417 1.00 31.89 ? 686 SER A OG 1 ATOM 5261 N N . THR A 1 651 ? 45.178 42.512 52.104 1.00 28.29 ? 687 THR A N 1 ATOM 5262 C CA . THR A 1 651 ? 46.165 43.559 52.308 1.00 26.51 ? 687 THR A CA 1 ATOM 5263 C C . THR A 1 651 ? 47.549 42.975 52.524 1.00 28.83 ? 687 THR A C 1 ATOM 5264 O O . THR A 1 651 ? 47.687 41.863 53.038 1.00 28.92 ? 687 THR A O 1 ATOM 5265 C CB . THR A 1 651 ? 45.848 44.392 53.547 1.00 30.38 ? 687 THR A CB 1 ATOM 5266 O OG1 . THR A 1 651 ? 46.213 43.645 54.713 1.00 30.03 ? 687 THR A OG1 1 ATOM 5267 C CG2 . THR A 1 651 ? 44.364 44.754 53.589 1.00 29.58 ? 687 THR A CG2 1 ATOM 5268 N N . VAL A 1 652 ? 48.576 43.740 52.156 1.00 28.09 ? 688 VAL A N 1 ATOM 5269 C CA . VAL A 1 652 ? 49.959 43.394 52.494 1.00 26.14 ? 688 VAL A CA 1 ATOM 5270 C C . VAL A 1 652 ? 50.191 43.454 54.019 1.00 30.01 ? 688 VAL A C 1 ATOM 5271 O O . VAL A 1 652 ? 50.859 42.588 54.602 1.00 28.51 ? 688 VAL A O 1 ATOM 5272 C CB . VAL A 1 652 ? 50.951 44.355 51.792 1.00 23.74 ? 688 VAL A CB 1 ATOM 5273 C CG1 . VAL A 1 652 ? 52.373 44.117 52.285 1.00 26.84 ? 688 VAL A CG1 1 ATOM 5274 C CG2 . VAL A 1 652 ? 50.862 44.193 50.268 1.00 23.44 ? 688 VAL A CG2 1 ATOM 5275 N N . MET A 1 653 ? 49.635 44.482 54.656 1.00 26.07 ? 689 MET A N 1 ATOM 5276 C CA . MET A 1 653 ? 49.838 44.716 56.085 1.00 30.64 ? 689 MET A CA 1 ATOM 5277 C C . MET A 1 653 ? 49.560 43.492 56.959 1.00 31.52 ? 689 MET A C 1 ATOM 5278 O O . MET A 1 653 ? 50.302 43.236 57.905 1.00 29.19 ? 689 MET A O 1 ATOM 5279 C CB . MET A 1 653 ? 49.001 45.903 56.566 1.00 29.33 ? 689 MET A CB 1 ATOM 5280 C CG . MET A 1 653 ? 49.622 47.255 56.229 1.00 32.39 ? 689 MET A CG 1 ATOM 5281 S SD . MET A 1 653 ? 49.443 47.686 54.475 1.00 31.00 ? 689 MET A SD 1 ATOM 5282 C CE . MET A 1 653 ? 47.726 48.168 54.470 1.00 26.49 ? 689 MET A CE 1 ATOM 5283 N N . SER A 1 654 ? 48.514 42.729 56.633 1.00 29.09 ? 690 SER A N 1 ATOM 5284 C CA . SER A 1 654 ? 48.130 41.586 57.463 1.00 33.18 ? 690 SER A CA 1 ATOM 5285 C C . SER A 1 654 ? 49.126 40.426 57.366 1.00 35.59 ? 690 SER A C 1 ATOM 5286 O O . SER A 1 654 ? 49.041 39.484 58.148 1.00 36.04 ? 690 SER A O 1 ATOM 5287 C CB . SER A 1 654 ? 46.703 41.103 57.145 1.00 31.81 ? 690 SER A CB 1 ATOM 5288 O OG . SER A 1 654 ? 46.630 40.520 55.846 1.00 36.30 ? 690 SER A OG 1 ATOM 5289 N N . ARG A 1 655 ? 50.065 40.490 56.417 1.00 31.45 ? 691 ARG A N 1 ATOM 5290 C CA . ARG A 1 655 ? 51.092 39.449 56.290 1.00 30.81 ? 691 ARG A CA 1 ATOM 5291 C C . ARG A 1 655 ? 52.448 39.858 56.878 1.00 32.75 ? 691 ARG A C 1 ATOM 5292 O O . ARG A 1 655 ? 53.442 39.155 56.692 1.00 29.17 ? 691 ARG A O 1 ATOM 5293 C CB . ARG A 1 655 ? 51.275 39.043 54.824 1.00 28.89 ? 691 ARG A CB 1 ATOM 5294 C CG . ARG A 1 655 ? 49.976 38.663 54.157 1.00 30.15 ? 691 ARG A CG 1 ATOM 5295 C CD . ARG A 1 655 ? 50.171 38.161 52.729 1.00 31.59 ? 691 ARG A CD 1 ATOM 5296 N NE . ARG A 1 655 ? 48.931 37.556 52.250 1.00 32.65 ? 691 ARG A NE 1 ATOM 5297 C CZ . ARG A 1 655 ? 48.860 36.689 51.248 1.00 35.53 ? 691 ARG A CZ 1 ATOM 5298 N NH1 . ARG A 1 655 ? 49.962 36.326 50.594 1.00 28.99 ? 691 ARG A NH1 1 ATOM 5299 N NH2 . ARG A 1 655 ? 47.682 36.184 50.903 1.00 37.52 ? 691 ARG A NH2 1 ATOM 5300 N N . ALA A 1 656 ? 52.484 40.984 57.585 1.00 27.79 ? 692 ALA A N 1 ATOM 5301 C CA . ALA A 1 656 ? 53.737 41.551 58.076 1.00 28.64 ? 692 ALA A CA 1 ATOM 5302 C C . ALA A 1 656 ? 54.659 40.546 58.782 1.00 28.95 ? 692 ALA A C 1 ATOM 5303 O O . ALA A 1 656 ? 55.860 40.494 58.495 1.00 26.31 ? 692 ALA A O 1 ATOM 5304 C CB . ALA A 1 656 ? 53.439 42.751 58.995 1.00 29.65 ? 692 ALA A CB 1 ATOM 5305 N N . GLU A 1 657 ? 54.107 39.753 59.702 1.00 28.71 ? 693 GLU A N 1 ATOM 5306 C CA . GLU A 1 657 ? 54.922 38.819 60.476 1.00 28.31 ? 693 GLU A CA 1 ATOM 5307 C C . GLU A 1 657 ? 55.773 37.913 59.580 1.00 32.56 ? 693 GLU A C 1 ATOM 5308 O O . GLU A 1 657 ? 56.902 37.573 59.916 1.00 29.86 ? 693 GLU A O 1 ATOM 5309 C CB . GLU A 1 657 ? 54.054 37.962 61.408 1.00 32.95 ? 693 GLU A CB 1 ATOM 5310 C CG . GLU A 1 657 ? 53.484 38.704 62.639 1.00 45.30 ? 693 GLU A CG 1 ATOM 5311 C CD . GLU A 1 657 ? 54.432 38.702 63.860 1.00 52.84 ? 693 GLU A CD 1 ATOM 5312 O OE1 . GLU A 1 657 ? 55.559 38.146 63.762 1.00 50.58 ? 693 GLU A OE1 1 ATOM 5313 O OE2 . GLU A 1 657 ? 54.036 39.254 64.920 1.00 53.07 ? 693 GLU A OE2 1 ATOM 5314 N N . ASN A 1 658 ? 55.223 37.528 58.437 1.00 31.09 ? 694 ASN A N 1 ATOM 5315 C CA . ASN A 1 658 ? 55.884 36.575 57.563 1.00 28.65 ? 694 ASN A CA 1 ATOM 5316 C C . ASN A 1 658 ? 57.119 37.141 56.870 1.00 32.29 ? 694 ASN A C 1 ATOM 5317 O O . ASN A 1 658 ? 57.960 36.387 56.381 1.00 32.45 ? 694 ASN A O 1 ATOM 5318 C CB . ASN A 1 658 ? 54.886 36.030 56.544 1.00 28.55 ? 694 ASN A CB 1 ATOM 5319 C CG . ASN A 1 658 ? 54.015 34.928 57.120 1.00 36.41 ? 694 ASN A CG 1 ATOM 5320 O OD1 . ASN A 1 658 ? 54.436 34.199 58.013 1.00 36.03 ? 694 ASN A OD1 1 ATOM 5321 N ND2 . ASN A 1 658 ? 52.800 34.794 56.601 1.00 41.02 ? 694 ASN A ND2 1 ATOM 5322 N N . PHE A 1 659 ? 57.233 38.467 56.833 1.00 29.65 ? 695 PHE A N 1 ATOM 5323 C CA . PHE A 1 659 ? 58.416 39.112 56.265 1.00 26.00 ? 695 PHE A CA 1 ATOM 5324 C C . PHE A 1 659 ? 59.684 38.914 57.104 1.00 30.00 ? 695 PHE A C 1 ATOM 5325 O O . PHE A 1 659 ? 60.764 39.329 56.694 1.00 27.80 ? 695 PHE A O 1 ATOM 5326 C CB . PHE A 1 659 ? 58.180 40.609 56.060 1.00 28.46 ? 695 PHE A CB 1 ATOM 5327 C CG . PHE A 1 659 ? 57.263 40.939 54.909 1.00 26.55 ? 695 PHE A CG 1 ATOM 5328 C CD1 . PHE A 1 659 ? 55.900 40.721 55.003 1.00 24.50 ? 695 PHE A CD1 1 ATOM 5329 C CD2 . PHE A 1 659 ? 57.767 41.510 53.753 1.00 26.93 ? 695 PHE A CD2 1 ATOM 5330 C CE1 . PHE A 1 659 ? 55.045 41.053 53.952 1.00 30.16 ? 695 PHE A CE1 1 ATOM 5331 C CE2 . PHE A 1 659 ? 56.923 41.840 52.694 1.00 29.20 ? 695 PHE A CE2 1 ATOM 5332 C CZ . PHE A 1 659 ? 55.563 41.607 52.796 1.00 29.51 ? 695 PHE A CZ 1 ATOM 5333 N N . LYS A 1 660 ? 59.572 38.286 58.274 1.00 32.80 ? 696 LYS A N 1 ATOM 5334 C CA . LYS A 1 660 ? 60.784 37.971 59.032 1.00 33.23 ? 696 LYS A CA 1 ATOM 5335 C C . LYS A 1 660 ? 61.624 36.913 58.306 1.00 36.51 ? 696 LYS A C 1 ATOM 5336 O O . LYS A 1 660 ? 62.824 36.786 58.544 1.00 37.68 ? 696 LYS A O 1 ATOM 5337 C CB . LYS A 1 660 ? 60.459 37.524 60.461 1.00 34.99 ? 696 LYS A CB 1 ATOM 5338 C CG . LYS A 1 660 ? 59.593 36.284 60.537 1.00 41.76 ? 696 LYS A CG 1 ATOM 5339 N N . GLN A 1 661 ? 61.000 36.164 57.402 1.00 33.11 ? 697 GLN A N 1 ATOM 5340 C CA . GLN A 1 661 ? 61.710 35.106 56.685 1.00 34.74 ? 697 GLN A CA 1 ATOM 5341 C C . GLN A 1 661 ? 62.469 35.587 55.431 1.00 38.08 ? 697 GLN A C 1 ATOM 5342 O O . GLN A 1 661 ? 63.126 34.787 54.765 1.00 37.32 ? 697 GLN A O 1 ATOM 5343 C CB . GLN A 1 661 ? 60.729 33.996 56.287 1.00 37.62 ? 697 GLN A CB 1 ATOM 5344 C CG . GLN A 1 661 ? 59.921 33.401 57.445 1.00 46.02 ? 697 GLN A CG 1 ATOM 5345 C CD . GLN A 1 661 ? 58.889 32.386 56.963 1.00 50.68 ? 697 GLN A CD 1 ATOM 5346 O OE1 . GLN A 1 661 ? 59.136 31.636 56.014 1.00 51.75 ? 697 GLN A OE1 1 ATOM 5347 N NE2 . GLN A 1 661 ? 57.723 32.371 57.607 1.00 44.87 ? 697 GLN A NE2 1 ATOM 5348 N N . VAL A 1 662 ? 62.375 36.872 55.091 1.00 32.59 ? 698 VAL A N 1 ATOM 5349 C CA . VAL A 1 662 ? 62.942 37.348 53.821 1.00 29.98 ? 698 VAL A CA 1 ATOM 5350 C C . VAL A 1 662 ? 63.637 38.710 53.914 1.00 27.27 ? 698 VAL A C 1 ATOM 5351 O O . VAL A 1 662 ? 63.429 39.457 54.867 1.00 28.62 ? 698 VAL A O 1 ATOM 5352 C CB . VAL A 1 662 ? 61.837 37.459 52.742 1.00 33.43 ? 698 VAL A CB 1 ATOM 5353 C CG1 . VAL A 1 662 ? 60.979 36.197 52.715 1.00 32.79 ? 698 VAL A CG1 1 ATOM 5354 C CG2 . VAL A 1 662 ? 60.971 38.695 52.997 1.00 27.37 ? 698 VAL A CG2 1 ATOM 5355 N N . GLU A 1 663 ? 64.460 39.037 52.925 1.00 28.24 ? 699 GLU A N 1 ATOM 5356 C CA . GLU A 1 663 ? 65.001 40.399 52.795 1.00 31.71 ? 699 GLU A CA 1 ATOM 5357 C C . GLU A 1 663 ? 64.135 41.190 51.821 1.00 29.39 ? 699 GLU A C 1 ATOM 5358 O O . GLU A 1 663 ? 63.944 40.767 50.691 1.00 29.57 ? 699 GLU A O 1 ATOM 5359 C CB . GLU A 1 663 ? 66.424 40.376 52.249 1.00 37.31 ? 699 GLU A CB 1 ATOM 5360 C CG . GLU A 1 663 ? 67.416 39.525 53.020 1.00 42.95 ? 699 GLU A CG 1 ATOM 5361 C CD . GLU A 1 663 ? 68.789 39.505 52.344 1.00 58.53 ? 699 GLU A CD 1 ATOM 5362 O OE1 . GLU A 1 663 ? 69.259 40.590 51.910 1.00 55.03 ? 699 GLU A OE1 1 ATOM 5363 O OE2 . GLU A 1 663 ? 69.384 38.402 52.233 1.00 58.82 ? 699 GLU A OE2 1 ATOM 5364 N N . TYR A 1 664 ? 63.646 42.347 52.239 1.00 24.78 ? 700 TYR A N 1 ATOM 5365 C CA . TYR A 1 664 ? 62.651 43.098 51.479 1.00 22.96 ? 700 TYR A CA 1 ATOM 5366 C C . TYR A 1 664 ? 63.169 44.507 51.278 1.00 30.52 ? 700 TYR A C 1 ATOM 5367 O O . TYR A 1 664 ? 63.659 45.146 52.231 1.00 27.16 ? 700 TYR A O 1 ATOM 5368 C CB . TYR A 1 664 ? 61.373 43.166 52.305 1.00 25.33 ? 700 TYR A CB 1 ATOM 5369 C CG . TYR A 1 664 ? 60.147 43.853 51.716 1.00 27.51 ? 700 TYR A CG 1 ATOM 5370 C CD1 . TYR A 1 664 ? 59.702 43.581 50.425 1.00 25.97 ? 700 TYR A CD1 1 ATOM 5371 C CD2 . TYR A 1 664 ? 59.380 44.714 52.502 1.00 23.92 ? 700 TYR A CD2 1 ATOM 5372 C CE1 . TYR A 1 664 ? 58.534 44.183 49.919 1.00 24.99 ? 700 TYR A CE1 1 ATOM 5373 C CE2 . TYR A 1 664 ? 58.227 45.315 52.014 1.00 23.87 ? 700 TYR A CE2 1 ATOM 5374 C CZ . TYR A 1 664 ? 57.798 45.045 50.726 1.00 25.64 ? 700 TYR A CZ 1 ATOM 5375 O OH . TYR A 1 664 ? 56.649 45.652 50.263 1.00 22.29 ? 700 TYR A OH 1 ATOM 5376 N N . LEU A 1 665 ? 63.057 44.999 50.047 1.00 25.43 ? 701 LEU A N 1 ATOM 5377 C CA . LEU A 1 665 ? 63.374 46.381 49.756 1.00 24.76 ? 701 LEU A CA 1 ATOM 5378 C C . LEU A 1 665 ? 62.100 47.047 49.254 1.00 25.39 ? 701 LEU A C 1 ATOM 5379 O O . LEU A 1 665 ? 61.530 46.612 48.255 1.00 23.77 ? 701 LEU A O 1 ATOM 5380 C CB . LEU A 1 665 ? 64.486 46.456 48.703 1.00 23.12 ? 701 LEU A CB 1 ATOM 5381 C CG . LEU A 1 665 ? 64.838 47.830 48.115 1.00 22.83 ? 701 LEU A CG 1 ATOM 5382 C CD1 . LEU A 1 665 ? 65.186 48.840 49.193 1.00 25.29 ? 701 LEU A CD1 1 ATOM 5383 C CD2 . LEU A 1 665 ? 65.999 47.697 47.144 1.00 24.32 ? 701 LEU A CD2 1 ATOM 5384 N N . LEU A 1 666 ? 61.653 48.091 49.954 1.00 24.44 ? 702 LEU A N 1 ATOM 5385 C CA . LEU A 1 666 ? 60.431 48.819 49.600 1.00 24.18 ? 702 LEU A CA 1 ATOM 5386 C C . LEU A 1 666 ? 60.782 50.215 49.091 1.00 25.59 ? 702 LEU A C 1 ATOM 5387 O O . LEU A 1 666 ? 61.473 50.976 49.779 1.00 26.35 ? 702 LEU A O 1 ATOM 5388 C CB . LEU A 1 666 ? 59.516 48.917 50.831 1.00 26.47 ? 702 LEU A CB 1 ATOM 5389 C CG . LEU A 1 666 ? 58.187 49.664 50.760 1.00 24.10 ? 702 LEU A CG 1 ATOM 5390 C CD1 . LEU A 1 666 ? 57.205 49.005 49.778 1.00 23.32 ? 702 LEU A CD1 1 ATOM 5391 C CD2 . LEU A 1 666 ? 57.557 49.752 52.142 1.00 23.41 ? 702 LEU A CD2 1 ATOM 5392 N N . ILE A 1 667 ? 60.311 50.555 47.894 1.00 23.11 ? 703 ILE A N 1 ATOM 5393 C CA . ILE A 1 667 ? 60.660 51.830 47.266 1.00 23.48 ? 703 ILE A CA 1 ATOM 5394 C C . ILE A 1 667 ? 59.411 52.554 46.814 1.00 24.88 ? 703 ILE A C 1 ATOM 5395 O O . ILE A 1 667 ? 58.513 51.925 46.253 1.00 24.81 ? 703 ILE A O 1 ATOM 5396 C CB . ILE A 1 667 ? 61.572 51.599 46.037 1.00 21.55 ? 703 ILE A CB 1 ATOM 5397 C CG1 . ILE A 1 667 ? 62.756 50.705 46.420 1.00 23.29 ? 703 ILE A CG1 1 ATOM 5398 C CG2 . ILE A 1 667 ? 62.029 52.924 45.445 1.00 22.22 ? 703 ILE A CG2 1 ATOM 5399 C CD1 . ILE A 1 667 ? 63.811 50.523 45.334 1.00 23.05 ? 703 ILE A CD1 1 ATOM 5400 N N . HIS A 1 668 ? 59.344 53.870 47.033 1.00 24.28 ? 704 HIS A N 1 ATOM 5401 C CA . HIS A 1 668 ? 58.180 54.647 46.588 1.00 23.57 ? 704 HIS A CA 1 ATOM 5402 C C . HIS A 1 668 ? 58.530 56.119 46.352 1.00 22.46 ? 704 HIS A C 1 ATOM 5403 O O . HIS A 1 668 ? 59.289 56.706 47.108 1.00 24.32 ? 704 HIS A O 1 ATOM 5404 C CB . HIS A 1 668 ? 57.059 54.564 47.650 1.00 25.55 ? 704 HIS A CB 1 ATOM 5405 C CG . HIS A 1 668 ? 55.668 54.554 47.083 1.00 21.93 ? 704 HIS A CG 1 ATOM 5406 N ND1 . HIS A 1 668 ? 54.774 53.536 47.337 1.00 20.44 ? 704 HIS A ND1 1 ATOM 5407 C CD2 . HIS A 1 668 ? 55.011 55.440 46.293 1.00 24.59 ? 704 HIS A CD2 1 ATOM 5408 C CE1 . HIS A 1 668 ? 53.634 53.783 46.713 1.00 20.99 ? 704 HIS A CE1 1 ATOM 5409 N NE2 . HIS A 1 668 ? 53.749 54.936 46.076 1.00 21.30 ? 704 HIS A NE2 1 ATOM 5410 N N . GLY A 1 669 ? 57.940 56.733 45.337 1.00 24.98 ? 705 GLY A N 1 ATOM 5411 C CA . GLY A 1 669 ? 58.116 58.165 45.128 1.00 22.59 ? 705 GLY A CA 1 ATOM 5412 C C . GLY A 1 669 ? 57.132 58.982 45.962 1.00 24.98 ? 705 GLY A C 1 ATOM 5413 O O . GLY A 1 669 ? 55.955 58.631 46.062 1.00 24.86 ? 705 GLY A O 1 ATOM 5414 N N . THR A 1 670 ? 57.586 60.086 46.545 1.00 25.51 ? 706 THR A N 1 ATOM 5415 C CA . THR A 1 670 ? 56.734 60.811 47.480 1.00 27.45 ? 706 THR A CA 1 ATOM 5416 C C . THR A 1 670 ? 55.624 61.598 46.795 1.00 28.41 ? 706 THR A C 1 ATOM 5417 O O . THR A 1 670 ? 54.616 61.913 47.425 1.00 28.32 ? 706 THR A O 1 ATOM 5418 C CB . THR A 1 670 ? 57.532 61.756 48.407 1.00 30.11 ? 706 THR A CB 1 ATOM 5419 O OG1 . THR A 1 670 ? 58.091 62.823 47.634 1.00 25.41 ? 706 THR A OG1 1 ATOM 5420 C CG2 . THR A 1 670 ? 58.643 60.990 49.133 1.00 22.89 ? 706 THR A CG2 1 ATOM 5421 N N . ALA A 1 671 ? 55.802 61.923 45.521 1.00 22.78 ? 707 ALA A N 1 ATOM 5422 C CA . ALA A 1 671 ? 54.765 62.667 44.805 1.00 28.22 ? 707 ALA A CA 1 ATOM 5423 C C . ALA A 1 671 ? 53.973 61.754 43.880 1.00 25.93 ? 707 ALA A C 1 ATOM 5424 O O . ALA A 1 671 ? 53.507 62.188 42.832 1.00 24.79 ? 707 ALA A O 1 ATOM 5425 C CB . ALA A 1 671 ? 55.361 63.845 44.011 1.00 25.55 ? 707 ALA A CB 1 ATOM 5426 N N . ASP A 1 672 ? 53.819 60.496 44.269 1.00 22.50 ? 708 ASP A N 1 ATOM 5427 C CA . ASP A 1 672 ? 53.079 59.548 43.449 1.00 25.26 ? 708 ASP A CA 1 ATOM 5428 C C . ASP A 1 672 ? 51.593 59.876 43.561 1.00 24.07 ? 708 ASP A C 1 ATOM 5429 O O . ASP A 1 672 ? 50.981 59.635 44.595 1.00 23.08 ? 708 ASP A O 1 ATOM 5430 C CB . ASP A 1 672 ? 53.372 58.120 43.915 1.00 23.83 ? 708 ASP A CB 1 ATOM 5431 C CG . ASP A 1 672 ? 52.913 57.063 42.912 1.00 25.42 ? 708 ASP A CG 1 ATOM 5432 O OD1 . ASP A 1 672 ? 51.902 57.293 42.204 1.00 25.02 ? 708 ASP A OD1 1 ATOM 5433 O OD2 . ASP A 1 672 ? 53.564 56.000 42.836 1.00 21.26 ? 708 ASP A OD2 1 ATOM 5434 N N . ASP A 1 673 ? 51.032 60.456 42.500 1.00 25.10 ? 709 ASP A N 1 ATOM 5435 C CA . ASP A 1 673 ? 49.619 60.839 42.440 1.00 22.02 ? 709 ASP A CA 1 ATOM 5436 C C . ASP A 1 673 ? 48.736 59.641 42.116 1.00 23.23 ? 709 ASP A C 1 ATOM 5437 O O . ASP A 1 673 ? 47.522 59.721 42.228 1.00 23.32 ? 709 ASP A O 1 ATOM 5438 C CB . ASP A 1 673 ? 49.413 61.872 41.327 1.00 25.05 ? 709 ASP A CB 1 ATOM 5439 C CG . ASP A 1 673 ? 49.918 61.363 39.965 1.00 29.51 ? 709 ASP A CG 1 ATOM 5440 O OD1 . ASP A 1 673 ? 51.158 61.393 39.760 1.00 29.20 ? 709 ASP A OD1 1 ATOM 5441 O OD2 . ASP A 1 673 ? 49.092 60.931 39.110 1.00 29.44 ? 709 ASP A OD2 1 ATOM 5442 N N . ASN A 1 674 ? 49.352 58.535 41.714 1.00 22.62 ? 710 ASN A N 1 ATOM 5443 C CA . ASN A 1 674 ? 48.625 57.360 41.247 1.00 22.70 ? 710 ASN A CA 1 ATOM 5444 C C . ASN A 1 674 ? 48.469 56.314 42.348 1.00 24.49 ? 710 ASN A C 1 ATOM 5445 O O . ASN A 1 674 ? 47.377 56.110 42.861 1.00 25.03 ? 710 ASN A O 1 ATOM 5446 C CB . ASN A 1 674 ? 49.337 56.760 40.031 1.00 21.99 ? 710 ASN A CB 1 ATOM 5447 C CG . ASN A 1 674 ? 48.427 55.877 39.200 1.00 26.87 ? 710 ASN A CG 1 ATOM 5448 O OD1 . ASN A 1 674 ? 47.551 55.201 39.737 1.00 24.79 ? 710 ASN A OD1 1 ATOM 5449 N ND2 . ASN A 1 674 ? 48.629 55.882 37.879 1.00 24.41 ? 710 ASN A ND2 1 ATOM 5450 N N . VAL A 1 675 ? 49.560 55.641 42.693 1.00 23.61 ? 711 VAL A N 1 ATOM 5451 C CA . VAL A 1 675 ? 49.577 54.761 43.855 1.00 24.20 ? 711 VAL A CA 1 ATOM 5452 C C . VAL A 1 675 ? 50.210 55.584 44.960 1.00 22.78 ? 711 VAL A C 1 ATOM 5453 O O . VAL A 1 675 ? 51.417 55.786 44.955 1.00 22.29 ? 711 VAL A O 1 ATOM 5454 C CB . VAL A 1 675 ? 50.423 53.499 43.615 1.00 22.11 ? 711 VAL A CB 1 ATOM 5455 C CG1 . VAL A 1 675 ? 50.487 52.662 44.888 1.00 22.26 ? 711 VAL A CG1 1 ATOM 5456 C CG2 . VAL A 1 675 ? 49.828 52.676 42.481 1.00 24.96 ? 711 VAL A CG2 1 ATOM 5457 N N . HIS A 1 676 ? 49.393 56.084 45.882 1.00 22.93 ? 712 HIS A N 1 ATOM 5458 C CA . HIS A 1 676 ? 49.834 57.131 46.801 1.00 24.18 ? 712 HIS A CA 1 ATOM 5459 C C . HIS A 1 676 ? 50.920 56.635 47.732 1.00 22.70 ? 712 HIS A C 1 ATOM 5460 O O . HIS A 1 676 ? 50.928 55.459 48.098 1.00 20.95 ? 712 HIS A O 1 ATOM 5461 C CB . HIS A 1 676 ? 48.623 57.684 47.558 1.00 23.95 ? 712 HIS A CB 1 ATOM 5462 C CG . HIS A 1 676 ? 47.573 58.209 46.639 1.00 25.57 ? 712 HIS A CG 1 ATOM 5463 N ND1 . HIS A 1 676 ? 46.225 58.066 46.870 1.00 23.12 ? 712 HIS A ND1 1 ATOM 5464 C CD2 . HIS A 1 676 ? 47.687 58.848 45.450 1.00 24.33 ? 712 HIS A CD2 1 ATOM 5465 C CE1 . HIS A 1 676 ? 45.549 58.615 45.878 1.00 26.33 ? 712 HIS A CE1 1 ATOM 5466 N NE2 . HIS A 1 676 ? 46.414 59.079 44.992 1.00 26.88 ? 712 HIS A NE2 1 ATOM 5467 N N . PHE A 1 677 ? 51.855 57.514 48.089 1.00 22.51 ? 713 PHE A N 1 ATOM 5468 C CA . PHE A 1 677 ? 52.921 57.120 49.008 1.00 22.36 ? 713 PHE A CA 1 ATOM 5469 C C . PHE A 1 677 ? 52.336 56.444 50.252 1.00 20.82 ? 713 PHE A C 1 ATOM 5470 O O . PHE A 1 677 ? 52.951 55.564 50.842 1.00 25.53 ? 713 PHE A O 1 ATOM 5471 C CB . PHE A 1 677 ? 53.759 58.328 49.434 1.00 26.82 ? 713 PHE A CB 1 ATOM 5472 C CG . PHE A 1 677 ? 54.930 57.963 50.305 1.00 23.89 ? 713 PHE A CG 1 ATOM 5473 C CD1 . PHE A 1 677 ? 54.840 58.052 51.676 1.00 27.20 ? 713 PHE A CD1 1 ATOM 5474 C CD2 . PHE A 1 677 ? 56.117 57.517 49.739 1.00 26.12 ? 713 PHE A CD2 1 ATOM 5475 C CE1 . PHE A 1 677 ? 55.925 57.699 52.485 1.00 29.36 ? 713 PHE A CE1 1 ATOM 5476 C CE2 . PHE A 1 677 ? 57.202 57.171 50.528 1.00 26.72 ? 713 PHE A CE2 1 ATOM 5477 C CZ . PHE A 1 677 ? 57.107 57.253 51.903 1.00 26.52 ? 713 PHE A CZ 1 ATOM 5478 N N . GLN A 1 678 ? 51.151 56.896 50.650 1.00 23.21 ? 714 GLN A N 1 ATOM 5479 C CA . GLN A 1 678 ? 50.352 56.271 51.707 1.00 22.49 ? 714 GLN A CA 1 ATOM 5480 C C . GLN A 1 678 ? 50.383 54.744 51.694 1.00 24.17 ? 714 GLN A C 1 ATOM 5481 O O . GLN A 1 678 ? 50.417 54.122 52.748 1.00 23.01 ? 714 GLN A O 1 ATOM 5482 C CB . GLN A 1 678 ? 48.898 56.727 51.595 1.00 22.43 ? 714 GLN A CB 1 ATOM 5483 C CG . GLN A 1 678 ? 47.923 55.904 52.429 1.00 24.91 ? 714 GLN A CG 1 ATOM 5484 C CD . GLN A 1 678 ? 46.498 56.109 51.964 1.00 28.04 ? 714 GLN A CD 1 ATOM 5485 O OE1 . GLN A 1 678 ? 46.253 56.228 50.774 1.00 26.09 ? 714 GLN A OE1 1 ATOM 5486 N NE2 . GLN A 1 678 ? 45.553 56.159 52.899 1.00 26.52 ? 714 GLN A NE2 1 ATOM 5487 N N . GLN A 1 679 ? 50.346 54.130 50.510 1.00 20.52 ? 715 GLN A N 1 ATOM 5488 C CA . GLN A 1 679 ? 50.304 52.666 50.460 1.00 23.01 ? 715 GLN A CA 1 ATOM 5489 C C . GLN A 1 679 ? 51.586 52.050 51.039 1.00 23.01 ? 715 GLN A C 1 ATOM 5490 O O . GLN A 1 679 ? 51.526 51.095 51.795 1.00 24.03 ? 715 GLN A O 1 ATOM 5491 C CB . GLN A 1 679 ? 50.033 52.154 49.026 1.00 22.78 ? 715 GLN A CB 1 ATOM 5492 C CG . GLN A 1 679 ? 48.905 52.913 48.313 1.00 20.62 ? 715 GLN A CG 1 ATOM 5493 C CD . GLN A 1 679 ? 47.820 52.010 47.743 1.00 27.04 ? 715 GLN A CD 1 ATOM 5494 O OE1 . GLN A 1 679 ? 47.628 50.883 48.194 1.00 26.75 ? 715 GLN A OE1 1 ATOM 5495 N NE2 . GLN A 1 679 ? 47.099 52.514 46.740 1.00 22.49 ? 715 GLN A NE2 1 ATOM 5496 N N . SER A 1 680 ? 52.747 52.586 50.676 1.00 21.50 ? 716 SER A N 1 ATOM 5497 C CA . SER A 1 680 ? 53.999 52.114 51.265 1.00 21.68 ? 716 SER A CA 1 ATOM 5498 C C . SER A 1 680 ? 54.167 52.610 52.715 1.00 23.66 ? 716 SER A C 1 ATOM 5499 O O . SER A 1 680 ? 54.679 51.887 53.571 1.00 23.94 ? 716 SER A O 1 ATOM 5500 C CB . SER A 1 680 ? 55.204 52.512 50.408 1.00 22.41 ? 716 SER A CB 1 ATOM 5501 O OG . SER A 1 680 ? 55.245 51.732 49.227 1.00 25.09 ? 716 SER A OG 1 ATOM 5502 N N . ALA A 1 681 ? 53.713 53.826 52.994 1.00 23.18 ? 717 ALA A N 1 ATOM 5503 C CA . ALA A 1 681 ? 53.746 54.330 54.379 1.00 24.57 ? 717 ALA A CA 1 ATOM 5504 C C . ALA A 1 681 ? 53.064 53.345 55.333 1.00 27.05 ? 717 ALA A C 1 ATOM 5505 O O . ALA A 1 681 ? 53.543 53.125 56.446 1.00 23.47 ? 717 ALA A O 1 ATOM 5506 C CB . ALA A 1 681 ? 53.094 55.689 54.471 1.00 23.38 ? 717 ALA A CB 1 ATOM 5507 N N . GLN A 1 682 ? 51.968 52.729 54.888 1.00 27.39 ? 718 GLN A N 1 ATOM 5508 C CA . GLN A 1 682 ? 51.257 51.762 55.731 1.00 25.49 ? 718 GLN A CA 1 ATOM 5509 C C . GLN A 1 682 ? 51.951 50.397 55.781 1.00 26.79 ? 718 GLN A C 1 ATOM 5510 O O . GLN A 1 682 ? 51.941 49.724 56.815 1.00 27.58 ? 718 GLN A O 1 ATOM 5511 C CB . GLN A 1 682 ? 49.793 51.617 55.312 1.00 26.13 ? 718 GLN A CB 1 ATOM 5512 C CG . GLN A 1 682 ? 48.963 52.883 55.511 1.00 28.25 ? 718 GLN A CG 1 ATOM 5513 C CD . GLN A 1 682 ? 48.640 53.164 56.991 1.00 29.26 ? 718 GLN A CD 1 ATOM 5514 O OE1 . GLN A 1 682 ? 49.162 52.505 57.891 1.00 28.93 ? 718 GLN A OE1 1 ATOM 5515 N NE2 . GLN A 1 682 ? 47.776 54.141 57.233 1.00 28.16 ? 718 GLN A NE2 1 ATOM 5516 N N . ILE A 1 683 ? 52.585 49.990 54.689 1.00 25.02 ? 719 ILE A N 1 ATOM 5517 C CA . ILE A 1 683 ? 53.356 48.753 54.733 1.00 25.44 ? 719 ILE A CA 1 ATOM 5518 C C . ILE A 1 683 ? 54.492 48.870 55.738 1.00 24.17 ? 719 ILE A C 1 ATOM 5519 O O . ILE A 1 683 ? 54.693 47.975 56.554 1.00 24.58 ? 719 ILE A O 1 ATOM 5520 C CB . ILE A 1 683 ? 53.983 48.392 53.385 1.00 23.66 ? 719 ILE A CB 1 ATOM 5521 C CG1 . ILE A 1 683 ? 52.908 47.955 52.383 1.00 24.44 ? 719 ILE A CG1 1 ATOM 5522 C CG2 . ILE A 1 683 ? 54.990 47.273 53.585 1.00 21.74 ? 719 ILE A CG2 1 ATOM 5523 C CD1 . ILE A 1 683 ? 53.448 47.751 50.943 1.00 24.30 ? 719 ILE A CD1 1 ATOM 5524 N N . SER A 1 684 ? 55.270 49.951 55.660 1.00 24.18 ? 720 SER A N 1 ATOM 5525 C CA . SER A 1 684 ? 56.414 50.085 56.567 1.00 24.83 ? 720 SER A CA 1 ATOM 5526 C C . SER A 1 684 ? 55.969 50.148 58.020 1.00 23.28 ? 720 SER A C 1 ATOM 5527 O O . SER A 1 684 ? 56.637 49.594 58.890 1.00 24.64 ? 720 SER A O 1 ATOM 5528 C CB . SER A 1 684 ? 57.305 51.291 56.239 1.00 24.75 ? 720 SER A CB 1 ATOM 5529 O OG . SER A 1 684 ? 56.609 52.513 56.392 1.00 25.18 ? 720 SER A OG 1 ATOM 5530 N N . LYS A 1 685 ? 54.858 50.831 58.281 1.00 23.68 ? 721 LYS A N 1 ATOM 5531 C CA . LYS A 1 685 ? 54.333 50.936 59.643 1.00 24.41 ? 721 LYS A CA 1 ATOM 5532 C C . LYS A 1 685 ? 53.980 49.565 60.202 1.00 25.90 ? 721 LYS A C 1 ATOM 5533 O O . LYS A 1 685 ? 54.254 49.286 61.357 1.00 27.91 ? 721 LYS A O 1 ATOM 5534 C CB . LYS A 1 685 ? 53.134 51.883 59.714 1.00 24.54 ? 721 LYS A CB 1 ATOM 5535 C CG . LYS A 1 685 ? 52.550 52.029 61.113 1.00 26.80 ? 721 LYS A CG 1 ATOM 5536 C CD . LYS A 1 685 ? 51.999 53.428 61.342 1.00 28.00 ? 721 LYS A CD 1 ATOM 5537 C CE . LYS A 1 685 ? 50.882 53.736 60.354 1.00 31.14 ? 721 LYS A CE 1 ATOM 5538 N NZ . LYS A 1 685 ? 49.732 52.824 60.599 1.00 29.41 ? 721 LYS A NZ 1 ATOM 5539 N N . ALA A 1 686 ? 53.405 48.692 59.376 1.00 25.01 ? 722 ALA A N 1 ATOM 5540 C CA . ALA A 1 686 ? 53.032 47.348 59.820 1.00 26.43 ? 722 ALA A CA 1 ATOM 5541 C C . ALA A 1 686 ? 54.248 46.477 60.120 1.00 28.03 ? 722 ALA A C 1 ATOM 5542 O O . ALA A 1 686 ? 54.245 45.700 61.070 1.00 28.94 ? 722 ALA A O 1 ATOM 5543 C CB . ALA A 1 686 ? 52.163 46.669 58.768 1.00 30.86 ? 722 ALA A CB 1 ATOM 5544 N N . LEU A 1 687 ? 55.279 46.577 59.285 1.00 25.27 ? 723 LEU A N 1 ATOM 5545 C CA . LEU A 1 687 ? 56.528 45.849 59.522 1.00 23.33 ? 723 LEU A CA 1 ATOM 5546 C C . LEU A 1 687 ? 57.205 46.330 60.815 1.00 28.00 ? 723 LEU A C 1 ATOM 5547 O O . LEU A 1 687 ? 57.618 45.532 61.652 1.00 28.42 ? 723 LEU A O 1 ATOM 5548 C CB . LEU A 1 687 ? 57.475 46.021 58.329 1.00 22.18 ? 723 LEU A CB 1 ATOM 5549 C CG . LEU A 1 687 ? 56.985 45.407 57.015 1.00 24.29 ? 723 LEU A CG 1 ATOM 5550 C CD1 . LEU A 1 687 ? 57.965 45.691 55.872 1.00 24.77 ? 723 LEU A CD1 1 ATOM 5551 C CD2 . LEU A 1 687 ? 56.818 43.937 57.202 1.00 26.07 ? 723 LEU A CD2 1 ATOM 5552 N N . VAL A 1 688 ? 57.336 47.640 60.964 1.00 27.56 ? 724 VAL A N 1 ATOM 5553 C CA . VAL A 1 688 ? 57.841 48.202 62.213 1.00 26.39 ? 724 VAL A CA 1 ATOM 5554 C C . VAL A 1 688 ? 57.048 47.658 63.395 1.00 27.15 ? 724 VAL A C 1 ATOM 5555 O O . VAL A 1 688 ? 57.626 47.149 64.340 1.00 26.78 ? 724 VAL A O 1 ATOM 5556 C CB . VAL A 1 688 ? 57.782 49.744 62.219 1.00 27.50 ? 724 VAL A CB 1 ATOM 5557 C CG1 . VAL A 1 688 ? 58.095 50.287 63.626 1.00 26.74 ? 724 VAL A CG1 1 ATOM 5558 C CG2 . VAL A 1 688 ? 58.753 50.304 61.187 1.00 25.67 ? 724 VAL A CG2 1 ATOM 5559 N N . ASP A 1 689 ? 55.723 47.744 63.327 1.00 28.05 ? 725 ASP A N 1 ATOM 5560 C CA . ASP A 1 689 ? 54.882 47.377 64.468 1.00 30.56 ? 725 ASP A CA 1 ATOM 5561 C C . ASP A 1 689 ? 55.102 45.949 64.945 1.00 33.74 ? 725 ASP A C 1 ATOM 5562 O O . ASP A 1 689 ? 54.848 45.624 66.107 1.00 33.04 ? 725 ASP A O 1 ATOM 5563 C CB . ASP A 1 689 ? 53.401 47.606 64.160 1.00 29.48 ? 725 ASP A CB 1 ATOM 5564 C CG . ASP A 1 689 ? 53.004 49.063 64.292 1.00 34.97 ? 725 ASP A CG 1 ATOM 5565 O OD1 . ASP A 1 689 ? 53.880 49.874 64.673 1.00 35.44 ? 725 ASP A OD1 1 ATOM 5566 O OD2 . ASP A 1 689 ? 51.825 49.395 64.022 1.00 40.32 ? 725 ASP A OD2 1 ATOM 5567 N N . VAL A 1 690 ? 55.620 45.118 64.052 1.00 28.85 ? 726 VAL A N 1 ATOM 5568 C CA . VAL A 1 690 ? 55.745 43.698 64.304 1.00 31.12 ? 726 VAL A CA 1 ATOM 5569 C C . VAL A 1 690 ? 57.217 43.271 64.455 1.00 32.37 ? 726 VAL A C 1 ATOM 5570 O O . VAL A 1 690 ? 57.523 42.090 64.609 1.00 32.79 ? 726 VAL A O 1 ATOM 5571 C CB . VAL A 1 690 ? 54.990 42.931 63.180 1.00 37.76 ? 726 VAL A CB 1 ATOM 5572 C CG1 . VAL A 1 690 ? 55.922 42.091 62.324 1.00 35.17 ? 726 VAL A CG1 1 ATOM 5573 C CG2 . VAL A 1 690 ? 53.838 42.131 63.760 1.00 44.33 ? 726 VAL A CG2 1 ATOM 5574 N N . GLY A 1 691 ? 58.126 44.242 64.412 1.00 29.37 ? 727 GLY A N 1 ATOM 5575 C CA . GLY A 1 691 ? 59.543 43.989 64.644 1.00 28.10 ? 727 GLY A CA 1 ATOM 5576 C C . GLY A 1 691 ? 60.322 43.366 63.495 1.00 32.74 ? 727 GLY A C 1 ATOM 5577 O O . GLY A 1 691 ? 61.291 42.648 63.733 1.00 30.81 ? 727 GLY A O 1 ATOM 5578 N N . VAL A 1 692 ? 59.910 43.635 62.253 1.00 28.31 ? 728 VAL A N 1 ATOM 5579 C CA . VAL A 1 692 ? 60.568 43.048 61.083 1.00 29.44 ? 728 VAL A CA 1 ATOM 5580 C C . VAL A 1 692 ? 61.504 44.054 60.458 1.00 28.03 ? 728 VAL A C 1 ATOM 5581 O O . VAL A 1 692 ? 61.077 45.144 60.100 1.00 29.66 ? 728 VAL A O 1 ATOM 5582 C CB . VAL A 1 692 ? 59.553 42.628 59.992 1.00 26.55 ? 728 VAL A CB 1 ATOM 5583 C CG1 . VAL A 1 692 ? 60.282 42.230 58.739 1.00 27.45 ? 728 VAL A CG1 1 ATOM 5584 C CG2 . VAL A 1 692 ? 58.684 41.496 60.492 1.00 32.02 ? 728 VAL A CG2 1 ATOM 5585 N N . ASP A 1 693 ? 62.778 43.706 60.324 1.00 28.26 ? 729 ASP A N 1 ATOM 5586 C CA . ASP A 1 693 ? 63.710 44.601 59.649 1.00 30.72 ? 729 ASP A CA 1 ATOM 5587 C C . ASP A 1 693 ? 63.543 44.469 58.139 1.00 33.09 ? 729 ASP A C 1 ATOM 5588 O O . ASP A 1 693 ? 63.203 43.397 57.634 1.00 28.58 ? 729 ASP A O 1 ATOM 5589 C CB . ASP A 1 693 ? 65.164 44.323 60.045 1.00 35.38 ? 729 ASP A CB 1 ATOM 5590 C CG . ASP A 1 693 ? 66.104 45.439 59.597 1.00 37.62 ? 729 ASP A CG 1 ATOM 5591 O OD1 . ASP A 1 693 ? 65.715 46.628 59.712 1.00 33.62 ? 729 ASP A OD1 1 ATOM 5592 O OD2 . ASP A 1 693 ? 67.207 45.131 59.091 1.00 41.17 ? 729 ASP A OD2 1 ATOM 5593 N N . PHE A 1 694 ? 63.778 45.564 57.426 1.00 29.76 ? 730 PHE A N 1 ATOM 5594 C CA . PHE A 1 694 ? 63.643 45.576 55.977 1.00 29.13 ? 730 PHE A CA 1 ATOM 5595 C C . PHE A 1 694 ? 64.378 46.814 55.488 1.00 31.42 ? 730 PHE A C 1 ATOM 5596 O O . PHE A 1 694 ? 64.799 47.655 56.294 1.00 27.02 ? 730 PHE A O 1 ATOM 5597 C CB . PHE A 1 694 ? 62.171 45.654 55.584 1.00 24.76 ? 730 PHE A CB 1 ATOM 5598 C CG . PHE A 1 694 ? 61.488 46.924 56.039 1.00 27.59 ? 730 PHE A CG 1 ATOM 5599 C CD1 . PHE A 1 694 ? 61.033 47.057 57.350 1.00 27.34 ? 730 PHE A CD1 1 ATOM 5600 C CD2 . PHE A 1 694 ? 61.279 47.966 55.156 1.00 27.41 ? 730 PHE A CD2 1 ATOM 5601 C CE1 . PHE A 1 694 ? 60.412 48.228 57.769 1.00 27.70 ? 730 PHE A CE1 1 ATOM 5602 C CE2 . PHE A 1 694 ? 60.644 49.132 55.557 1.00 27.21 ? 730 PHE A CE2 1 ATOM 5603 C CZ . PHE A 1 694 ? 60.216 49.263 56.868 1.00 27.52 ? 730 PHE A CZ 1 ATOM 5604 N N . GLN A 1 695 ? 64.546 46.926 54.178 1.00 28.17 ? 731 GLN A N 1 ATOM 5605 C CA . GLN A 1 695 ? 65.212 48.088 53.593 1.00 25.82 ? 731 GLN A CA 1 ATOM 5606 C C . GLN A 1 695 ? 64.212 48.960 52.861 1.00 27.05 ? 731 GLN A C 1 ATOM 5607 O O . GLN A 1 695 ? 63.207 48.456 52.346 1.00 27.12 ? 731 GLN A O 1 ATOM 5608 C CB . GLN A 1 695 ? 66.256 47.621 52.599 1.00 32.83 ? 731 GLN A CB 1 ATOM 5609 C CG . GLN A 1 695 ? 67.061 46.457 53.085 1.00 39.67 ? 731 GLN A CG 1 ATOM 5610 C CD . GLN A 1 695 ? 68.506 46.815 53.186 1.00 50.65 ? 731 GLN A CD 1 ATOM 5611 O OE1 . GLN A 1 695 ? 69.287 46.578 52.252 1.00 55.11 ? 731 GLN A OE1 1 ATOM 5612 N NE2 . GLN A 1 695 ? 68.881 47.425 54.307 1.00 48.06 ? 731 GLN A NE2 1 ATOM 5613 N N . ALA A 1 696 ? 64.506 50.253 52.761 1.00 25.78 ? 732 ALA A N 1 ATOM 5614 C CA . ALA A 1 696 ? 63.561 51.189 52.163 1.00 26.58 ? 732 ALA A CA 1 ATOM 5615 C C . ALA A 1 696 ? 64.284 52.313 51.428 1.00 29.25 ? 732 ALA A C 1 ATOM 5616 O O . ALA A 1 696 ? 65.470 52.573 51.669 1.00 30.28 ? 732 ALA A O 1 ATOM 5617 C CB . ALA A 1 696 ? 62.647 51.774 53.246 1.00 25.32 ? 732 ALA A CB 1 ATOM 5618 N N . MET A 1 697 ? 63.561 52.986 50.543 1.00 22.78 ? 733 MET A N 1 ATOM 5619 C CA . MET A 1 697 ? 64.091 54.160 49.866 1.00 22.57 ? 733 MET A CA 1 ATOM 5620 C C . MET A 1 697 ? 62.915 54.972 49.376 1.00 26.20 ? 733 MET A C 1 ATOM 5621 O O . MET A 1 697 ? 62.062 54.452 48.651 1.00 26.02 ? 733 MET A O 1 ATOM 5622 C CB . MET A 1 697 ? 64.986 53.741 48.686 1.00 24.63 ? 733 MET A CB 1 ATOM 5623 C CG . MET A 1 697 ? 65.520 54.879 47.825 1.00 27.07 ? 733 MET A CG 1 ATOM 5624 S SD . MET A 1 697 ? 66.638 56.027 48.664 1.00 31.47 ? 733 MET A SD 1 ATOM 5625 C CE . MET A 1 697 ? 68.005 54.937 49.069 1.00 27.45 ? 733 MET A CE 1 ATOM 5626 N N . TRP A 1 698 ? 62.839 56.237 49.781 1.00 21.67 ? 734 TRP A N 1 ATOM 5627 C CA . TRP A 1 698 ? 61.844 57.125 49.207 1.00 22.64 ? 734 TRP A CA 1 ATOM 5628 C C . TRP A 1 698 ? 62.532 57.919 48.102 1.00 26.47 ? 734 TRP A C 1 ATOM 5629 O O . TRP A 1 698 ? 63.744 58.066 48.140 1.00 27.85 ? 734 TRP A O 1 ATOM 5630 C CB . TRP A 1 698 ? 61.278 58.072 50.264 1.00 23.43 ? 734 TRP A CB 1 ATOM 5631 C CG . TRP A 1 698 ? 62.228 59.147 50.706 1.00 23.36 ? 734 TRP A CG 1 ATOM 5632 C CD1 . TRP A 1 698 ? 62.481 60.320 50.070 1.00 23.21 ? 734 TRP A CD1 1 ATOM 5633 C CD2 . TRP A 1 698 ? 63.033 59.154 51.904 1.00 24.76 ? 734 TRP A CD2 1 ATOM 5634 N NE1 . TRP A 1 698 ? 63.399 61.064 50.790 1.00 24.77 ? 734 TRP A NE1 1 ATOM 5635 C CE2 . TRP A 1 698 ? 63.747 60.371 51.920 1.00 24.58 ? 734 TRP A CE2 1 ATOM 5636 C CE3 . TRP A 1 698 ? 63.208 58.254 52.963 1.00 23.93 ? 734 TRP A CE3 1 ATOM 5637 C CZ2 . TRP A 1 698 ? 64.638 60.710 52.951 1.00 23.68 ? 734 TRP A CZ2 1 ATOM 5638 C CZ3 . TRP A 1 698 ? 64.088 58.596 53.996 1.00 25.89 ? 734 TRP A CZ3 1 ATOM 5639 C CH2 . TRP A 1 698 ? 64.796 59.809 53.974 1.00 25.05 ? 734 TRP A CH2 1 ATOM 5640 N N . TYR A 1 699 ? 61.773 58.407 47.121 1.00 23.67 ? 735 TYR A N 1 ATOM 5641 C CA . TYR A 1 699 ? 62.318 59.293 46.082 1.00 24.75 ? 735 TYR A CA 1 ATOM 5642 C C . TYR A 1 699 ? 61.539 60.593 46.108 1.00 25.73 ? 735 TYR A C 1 ATOM 5643 O O . TYR A 1 699 ? 60.393 60.652 45.658 1.00 27.49 ? 735 TYR A O 1 ATOM 5644 C CB . TYR A 1 699 ? 62.307 58.642 44.671 1.00 24.54 ? 735 TYR A CB 1 ATOM 5645 C CG . TYR A 1 699 ? 63.460 57.676 44.502 1.00 25.09 ? 735 TYR A CG 1 ATOM 5646 C CD1 . TYR A 1 699 ? 64.746 58.134 44.224 1.00 24.99 ? 735 TYR A CD1 1 ATOM 5647 C CD2 . TYR A 1 699 ? 63.274 56.319 44.668 1.00 24.88 ? 735 TYR A CD2 1 ATOM 5648 C CE1 . TYR A 1 699 ? 65.812 57.248 44.123 1.00 26.91 ? 735 TYR A CE1 1 ATOM 5649 C CE2 . TYR A 1 699 ? 64.323 55.432 44.561 1.00 26.31 ? 735 TYR A CE2 1 ATOM 5650 C CZ . TYR A 1 699 ? 65.587 55.899 44.302 1.00 24.73 ? 735 TYR A CZ 1 ATOM 5651 O OH . TYR A 1 699 ? 66.616 54.997 44.212 1.00 26.66 ? 735 TYR A OH 1 ATOM 5652 N N . THR A 1 700 ? 62.166 61.633 46.652 1.00 23.48 ? 736 THR A N 1 ATOM 5653 C CA . THR A 1 700 ? 61.543 62.944 46.780 1.00 25.51 ? 736 THR A CA 1 ATOM 5654 C C . THR A 1 700 ? 61.015 63.506 45.462 1.00 25.95 ? 736 THR A C 1 ATOM 5655 O O . THR A 1 700 ? 61.770 63.658 44.519 1.00 28.59 ? 736 THR A O 1 ATOM 5656 C CB . THR A 1 700 ? 62.558 63.961 47.319 1.00 25.07 ? 736 THR A CB 1 ATOM 5657 O OG1 . THR A 1 700 ? 63.055 63.492 48.577 1.00 25.54 ? 736 THR A OG1 1 ATOM 5658 C CG2 . THR A 1 700 ? 61.911 65.328 47.470 1.00 21.86 ? 736 THR A CG2 1 ATOM 5659 N N . ASP A 1 701 ? 59.731 63.861 45.431 1.00 26.98 ? 737 ASP A N 1 ATOM 5660 C CA . ASP A 1 701 ? 59.114 64.546 44.287 1.00 25.39 ? 737 ASP A CA 1 ATOM 5661 C C . ASP A 1 701 ? 59.002 63.702 43.005 1.00 29.27 ? 737 ASP A C 1 ATOM 5662 O O . ASP A 1 701 ? 58.636 64.228 41.951 1.00 27.87 ? 737 ASP A O 1 ATOM 5663 C CB . ASP A 1 701 ? 59.800 65.898 43.989 1.00 27.46 ? 737 ASP A CB 1 ATOM 5664 C CG . ASP A 1 701 ? 59.529 66.966 45.083 1.00 33.37 ? 737 ASP A CG 1 ATOM 5665 O OD1 . ASP A 1 701 ? 58.669 66.737 45.971 1.00 29.70 ? 737 ASP A OD1 1 ATOM 5666 O OD2 . ASP A 1 701 ? 60.173 68.045 45.062 1.00 30.33 ? 737 ASP A OD2 1 ATOM 5667 N N . GLU A 1 702 ? 59.308 62.409 43.087 1.00 25.61 ? 738 GLU A N 1 ATOM 5668 C CA . GLU A 1 702 ? 59.102 61.503 41.949 1.00 24.98 ? 738 GLU A CA 1 ATOM 5669 C C . GLU A 1 702 ? 57.692 60.936 42.004 1.00 28.39 ? 738 GLU A C 1 ATOM 5670 O O . GLU A 1 702 ? 57.145 60.718 43.089 1.00 27.00 ? 738 GLU A O 1 ATOM 5671 C CB . GLU A 1 702 ? 60.106 60.355 41.976 1.00 26.23 ? 738 GLU A CB 1 ATOM 5672 C CG . GLU A 1 702 ? 61.545 60.784 41.750 1.00 23.63 ? 738 GLU A CG 1 ATOM 5673 C CD . GLU A 1 702 ? 61.738 61.403 40.374 1.00 36.42 ? 738 GLU A CD 1 ATOM 5674 O OE1 . GLU A 1 702 ? 61.400 60.739 39.359 1.00 38.30 ? 738 GLU A OE1 1 ATOM 5675 O OE2 . GLU A 1 702 ? 62.221 62.555 40.297 1.00 37.54 ? 738 GLU A OE2 1 ATOM 5676 N N . ASP A 1 703 ? 57.112 60.680 40.837 1.00 27.71 ? 739 ASP A N 1 ATOM 5677 C CA . ASP A 1 703 ? 55.762 60.152 40.771 1.00 25.79 ? 739 ASP A CA 1 ATOM 5678 C C . ASP A 1 703 ? 55.790 58.650 40.528 1.00 26.56 ? 739 ASP A C 1 ATOM 5679 O O . ASP A 1 703 ? 56.763 57.988 40.890 1.00 26.27 ? 739 ASP A O 1 ATOM 5680 C CB . ASP A 1 703 ? 54.904 60.916 39.749 1.00 25.85 ? 739 ASP A CB 1 ATOM 5681 C CG . ASP A 1 703 ? 55.376 60.746 38.293 1.00 34.22 ? 739 ASP A CG 1 ATOM 5682 O OD1 . ASP A 1 703 ? 56.288 59.931 37.998 1.00 33.16 ? 739 ASP A OD1 1 ATOM 5683 O OD2 . ASP A 1 703 ? 54.803 61.441 37.428 1.00 33.10 ? 739 ASP A OD2 1 ATOM 5684 N N . HIS A 1 704 ? 54.726 58.103 39.950 1.00 23.55 ? 740 HIS A N 1 ATOM 5685 C CA . HIS A 1 704 ? 54.617 56.650 39.823 1.00 27.10 ? 740 HIS A CA 1 ATOM 5686 C C . HIS A 1 704 ? 55.696 56.046 38.928 1.00 28.87 ? 740 HIS A C 1 ATOM 5687 O O . HIS A 1 704 ? 56.085 54.895 39.113 1.00 29.79 ? 740 HIS A O 1 ATOM 5688 C CB . HIS A 1 704 ? 53.246 56.226 39.289 1.00 24.72 ? 740 HIS A CB 1 ATOM 5689 C CG . HIS A 1 704 ? 52.959 54.776 39.497 1.00 25.30 ? 740 HIS A CG 1 ATOM 5690 N ND1 . HIS A 1 704 ? 52.962 54.199 40.747 1.00 23.53 ? 740 HIS A ND1 1 ATOM 5691 C CD2 . HIS A 1 704 ? 52.682 53.782 38.621 1.00 29.20 ? 740 HIS A CD2 1 ATOM 5692 C CE1 . HIS A 1 704 ? 52.689 52.911 40.632 1.00 30.67 ? 740 HIS A CE1 1 ATOM 5693 N NE2 . HIS A 1 704 ? 52.513 52.633 39.353 1.00 27.03 ? 740 HIS A NE2 1 ATOM 5694 N N . GLY A 1 705 ? 56.167 56.815 37.951 1.00 27.54 ? 741 GLY A N 1 ATOM 5695 C CA . GLY A 1 705 ? 57.144 56.298 37.004 1.00 31.37 ? 741 GLY A CA 1 ATOM 5696 C C . GLY A 1 705 ? 58.580 56.382 37.496 1.00 32.01 ? 741 GLY A C 1 ATOM 5697 O O . GLY A 1 705 ? 59.468 55.770 36.905 1.00 29.88 ? 741 GLY A O 1 ATOM 5698 N N . ILE A 1 706 ? 58.807 57.126 38.582 1.00 27.88 ? 742 ILE A N 1 ATOM 5699 C CA . ILE A 1 706 ? 60.159 57.389 39.072 1.00 29.84 ? 742 ILE A CA 1 ATOM 5700 C C . ILE A 1 706 ? 61.085 57.531 37.863 1.00 31.63 ? 742 ILE A C 1 ATOM 5701 O O . ILE A 1 706 ? 62.090 56.830 37.734 1.00 32.34 ? 742 ILE A O 1 ATOM 5702 C CB . ILE A 1 706 ? 60.660 56.289 40.039 1.00 28.38 ? 742 ILE A CB 1 ATOM 5703 C CG1 . ILE A 1 706 ? 59.625 56.025 41.127 1.00 27.26 ? 742 ILE A CG1 1 ATOM 5704 C CG2 . ILE A 1 706 ? 61.972 56.697 40.692 1.00 27.39 ? 742 ILE A CG2 1 ATOM 5705 C CD1 . ILE A 1 706 ? 59.983 54.901 42.044 1.00 27.35 ? 742 ILE A CD1 1 ATOM 5706 N N . ALA A 1 707 ? 60.728 58.459 36.983 1.00 32.62 ? 743 ALA A N 1 ATOM 5707 C CA . ALA A 1 707 ? 61.255 58.472 35.617 1.00 35.83 ? 743 ALA A CA 1 ATOM 5708 C C . ALA A 1 707 ? 62.161 59.643 35.264 1.00 37.37 ? 743 ALA A C 1 ATOM 5709 O O . ALA A 1 707 ? 62.716 59.684 34.157 1.00 34.28 ? 743 ALA A O 1 ATOM 5710 C CB . ALA A 1 707 ? 60.109 58.383 34.615 1.00 33.23 ? 743 ALA A CB 1 ATOM 5711 N N . SER A 1 708 ? 62.318 60.605 36.166 1.00 31.84 ? 744 SER A N 1 ATOM 5712 C CA . SER A 1 708 ? 63.277 61.662 35.879 1.00 32.99 ? 744 SER A CA 1 ATOM 5713 C C . SER A 1 708 ? 64.615 60.968 35.620 1.00 31.31 ? 744 SER A C 1 ATOM 5714 O O . SER A 1 708 ? 64.859 59.865 36.111 1.00 28.99 ? 744 SER A O 1 ATOM 5715 C CB . SER A 1 708 ? 63.378 62.677 37.029 1.00 34.60 ? 744 SER A CB 1 ATOM 5716 O OG . SER A 1 708 ? 64.015 62.118 38.170 1.00 34.94 ? 744 SER A OG 1 ATOM 5717 N N . SER A 1 709 ? 65.472 61.596 34.826 1.00 33.87 ? 745 SER A N 1 ATOM 5718 C CA . SER A 1 709 ? 66.721 60.961 34.430 1.00 32.55 ? 745 SER A CA 1 ATOM 5719 C C . SER A 1 709 ? 67.568 60.536 35.633 1.00 29.07 ? 745 SER A C 1 ATOM 5720 O O . SER A 1 709 ? 68.069 59.426 35.675 1.00 29.17 ? 745 SER A O 1 ATOM 5721 C CB . SER A 1 709 ? 67.528 61.885 33.518 1.00 41.11 ? 745 SER A CB 1 ATOM 5722 O OG . SER A 1 709 ? 68.813 61.339 33.281 1.00 46.49 ? 745 SER A OG 1 ATOM 5723 N N . THR A 1 710 ? 67.719 61.410 36.618 1.00 29.34 ? 746 THR A N 1 ATOM 5724 C CA . THR A 1 710 ? 68.566 61.067 37.762 1.00 32.24 ? 746 THR A CA 1 ATOM 5725 C C . THR A 1 710 ? 67.939 60.027 38.699 1.00 28.71 ? 746 THR A C 1 ATOM 5726 O O . THR A 1 710 ? 68.645 59.168 39.229 1.00 28.21 ? 746 THR A O 1 ATOM 5727 C CB . THR A 1 710 ? 68.977 62.302 38.554 1.00 28.75 ? 746 THR A CB 1 ATOM 5728 O OG1 . THR A 1 710 ? 67.808 63.031 38.915 1.00 31.89 ? 746 THR A OG1 1 ATOM 5729 C CG2 . THR A 1 710 ? 69.875 63.196 37.700 1.00 36.78 ? 746 THR A CG2 1 ATOM 5730 N N . ALA A 1 711 ? 66.623 60.085 38.890 1.00 28.82 ? 747 ALA A N 1 ATOM 5731 C CA . ALA A 1 711 ? 65.963 59.126 39.780 1.00 23.43 ? 747 ALA A CA 1 ATOM 5732 C C . ALA A 1 711 ? 65.981 57.724 39.166 1.00 27.44 ? 747 ALA A C 1 ATOM 5733 O O . ALA A 1 711 ? 66.227 56.722 39.857 1.00 27.00 ? 747 ALA A O 1 ATOM 5734 C CB . ALA A 1 711 ? 64.541 59.569 40.067 1.00 28.91 ? 747 ALA A CB 1 ATOM 5735 N N . HIS A 1 712 ? 65.724 57.664 37.859 1.00 26.78 ? 748 HIS A N 1 ATOM 5736 C CA . HIS A 1 712 ? 65.718 56.399 37.115 1.00 25.76 ? 748 HIS A CA 1 ATOM 5737 C C . HIS A 1 712 ? 67.075 55.725 37.242 1.00 24.03 ? 748 HIS A C 1 ATOM 5738 O O . HIS A 1 712 ? 67.178 54.542 37.532 1.00 23.82 ? 748 HIS A O 1 ATOM 5739 C CB . HIS A 1 712 ? 65.395 56.668 35.639 1.00 27.56 ? 748 HIS A CB 1 ATOM 5740 C CG . HIS A 1 712 ? 65.616 55.486 34.743 1.00 29.77 ? 748 HIS A CG 1 ATOM 5741 N ND1 . HIS A 1 712 ? 64.771 54.395 34.727 1.00 29.19 ? 748 HIS A ND1 1 ATOM 5742 C CD2 . HIS A 1 712 ? 66.581 55.227 33.826 1.00 29.88 ? 748 HIS A CD2 1 ATOM 5743 C CE1 . HIS A 1 712 ? 65.209 53.512 33.843 1.00 31.87 ? 748 HIS A CE1 1 ATOM 5744 N NE2 . HIS A 1 712 ? 66.305 53.993 33.282 1.00 32.83 ? 748 HIS A NE2 1 ATOM 5745 N N . GLN A 1 713 ? 68.137 56.492 37.027 1.00 27.67 ? 749 GLN A N 1 ATOM 5746 C CA . GLN A 1 713 ? 69.474 55.951 37.202 1.00 26.83 ? 749 GLN A CA 1 ATOM 5747 C C . GLN A 1 713 ? 69.695 55.511 38.641 1.00 28.52 ? 749 GLN A C 1 ATOM 5748 O O . GLN A 1 713 ? 70.258 54.434 38.897 1.00 26.05 ? 749 GLN A O 1 ATOM 5749 C CB . GLN A 1 713 ? 70.524 56.965 36.746 1.00 30.22 ? 749 GLN A CB 1 ATOM 5750 C CG . GLN A 1 713 ? 70.438 57.264 35.237 1.00 29.38 ? 749 GLN A CG 1 ATOM 5751 C CD . GLN A 1 713 ? 71.351 58.400 34.805 1.00 44.41 ? 749 GLN A CD 1 ATOM 5752 O OE1 . GLN A 1 713 ? 72.544 58.406 35.109 1.00 49.48 ? 749 GLN A OE1 1 ATOM 5753 N NE2 . GLN A 1 713 ? 70.789 59.373 34.096 1.00 42.27 ? 749 GLN A NE2 1 ATOM 5754 N N . HIS A 1 714 ? 69.218 56.317 39.588 1.00 24.37 ? 750 HIS A N 1 ATOM 5755 C CA . HIS A 1 714 ? 69.465 55.999 40.991 1.00 28.17 ? 750 HIS A CA 1 ATOM 5756 C C . HIS A 1 714 ? 68.754 54.726 41.426 1.00 29.12 ? 750 HIS A C 1 ATOM 5757 O O . HIS A 1 714 ? 69.339 53.901 42.142 1.00 27.56 ? 750 HIS A O 1 ATOM 5758 C CB . HIS A 1 714 ? 69.082 57.162 41.918 1.00 28.40 ? 750 HIS A CB 1 ATOM 5759 C CG . HIS A 1 714 ? 69.697 57.062 43.277 1.00 30.28 ? 750 HIS A CG 1 ATOM 5760 N ND1 . HIS A 1 714 ? 69.135 56.322 44.293 1.00 30.07 ? 750 HIS A ND1 1 ATOM 5761 C CD2 . HIS A 1 714 ? 70.835 57.593 43.784 1.00 30.88 ? 750 HIS A CD2 1 ATOM 5762 C CE1 . HIS A 1 714 ? 69.893 56.405 45.372 1.00 29.86 ? 750 HIS A CE1 1 ATOM 5763 N NE2 . HIS A 1 714 ? 70.931 57.172 45.089 1.00 32.23 ? 750 HIS A NE2 1 ATOM 5764 N N . ILE A 1 715 ? 67.500 54.547 41.001 1.00 26.84 ? 751 ILE A N 1 ATOM 5765 C CA . ILE A 1 715 ? 66.724 53.415 41.511 1.00 25.91 ? 751 ILE A CA 1 ATOM 5766 C C . ILE A 1 715 ? 67.210 52.090 40.933 1.00 26.09 ? 751 ILE A C 1 ATOM 5767 O O . ILE A 1 715 ? 67.227 51.083 41.624 1.00 25.39 ? 751 ILE A O 1 ATOM 5768 C CB . ILE A 1 715 ? 65.190 53.584 41.327 1.00 24.46 ? 751 ILE A CB 1 ATOM 5769 C CG1 . ILE A 1 715 ? 64.445 52.466 42.048 1.00 23.36 ? 751 ILE A CG1 1 ATOM 5770 C CG2 . ILE A 1 715 ? 64.808 53.584 39.866 1.00 24.14 ? 751 ILE A CG2 1 ATOM 5771 C CD1 . ILE A 1 715 ? 62.939 52.615 41.972 1.00 21.80 ? 751 ILE A CD1 1 ATOM 5772 N N . TYR A 1 716 ? 67.633 52.081 39.671 1.00 26.83 ? 752 TYR A N 1 ATOM 5773 C CA . TYR A 1 716 ? 68.118 50.825 39.100 1.00 26.05 ? 752 TYR A CA 1 ATOM 5774 C C . TYR A 1 716 ? 69.497 50.469 39.643 1.00 27.06 ? 752 TYR A C 1 ATOM 5775 O O . TYR A 1 716 ? 69.822 49.297 39.814 1.00 28.47 ? 752 TYR A O 1 ATOM 5776 C CB . TYR A 1 716 ? 68.073 50.837 37.574 1.00 24.53 ? 752 TYR A CB 1 ATOM 5777 C CG . TYR A 1 716 ? 66.684 50.554 37.053 1.00 24.96 ? 752 TYR A CG 1 ATOM 5778 C CD1 . TYR A 1 716 ? 66.206 49.257 36.989 1.00 26.43 ? 752 TYR A CD1 1 ATOM 5779 C CD2 . TYR A 1 716 ? 65.841 51.583 36.658 1.00 24.99 ? 752 TYR A CD2 1 ATOM 5780 C CE1 . TYR A 1 716 ? 64.937 48.985 36.515 1.00 26.59 ? 752 TYR A CE1 1 ATOM 5781 C CE2 . TYR A 1 716 ? 64.570 51.318 36.174 1.00 27.77 ? 752 TYR A CE2 1 ATOM 5782 C CZ . TYR A 1 716 ? 64.126 50.016 36.118 1.00 27.32 ? 752 TYR A CZ 1 ATOM 5783 O OH . TYR A 1 716 ? 62.868 49.731 35.653 1.00 32.82 ? 752 TYR A OH 1 ATOM 5784 N N . THR A 1 717 ? 70.286 51.490 39.948 1.00 25.09 ? 753 THR A N 1 ATOM 5785 C CA . THR A 1 717 ? 71.563 51.287 40.600 1.00 25.60 ? 753 THR A CA 1 ATOM 5786 C C . THR A 1 717 ? 71.352 50.734 42.005 1.00 27.35 ? 753 THR A C 1 ATOM 5787 O O . THR A 1 717 ? 72.008 49.782 42.397 1.00 29.76 ? 753 THR A O 1 ATOM 5788 C CB . THR A 1 717 ? 72.363 52.584 40.632 1.00 28.21 ? 753 THR A CB 1 ATOM 5789 O OG1 . THR A 1 717 ? 72.613 53.000 39.282 1.00 28.06 ? 753 THR A OG1 1 ATOM 5790 C CG2 . THR A 1 717 ? 73.690 52.383 41.348 1.00 33.93 ? 753 THR A CG2 1 ATOM 5791 N N . HIS A 1 718 ? 70.412 51.308 42.749 1.00 25.62 ? 754 HIS A N 1 ATOM 5792 C CA . HIS A 1 718 ? 70.105 50.831 44.089 1.00 25.64 ? 754 HIS A CA 1 ATOM 5793 C C . HIS A 1 718 ? 69.608 49.388 44.068 1.00 25.55 ? 754 HIS A C 1 ATOM 5794 O O . HIS A 1 718 ? 70.077 48.544 44.828 1.00 26.52 ? 754 HIS A O 1 ATOM 5795 C CB . HIS A 1 718 ? 69.066 51.745 44.751 1.00 25.72 ? 754 HIS A CB 1 ATOM 5796 C CG . HIS A 1 718 ? 69.022 51.628 46.243 1.00 30.27 ? 754 HIS A CG 1 ATOM 5797 N ND1 . HIS A 1 718 ? 70.058 52.041 47.053 1.00 28.20 ? 754 HIS A ND1 1 ATOM 5798 C CD2 . HIS A 1 718 ? 68.061 51.154 47.072 1.00 33.27 ? 754 HIS A CD2 1 ATOM 5799 C CE1 . HIS A 1 718 ? 69.742 51.813 48.316 1.00 31.80 ? 754 HIS A CE1 1 ATOM 5800 N NE2 . HIS A 1 718 ? 68.536 51.275 48.355 1.00 30.07 ? 754 HIS A NE2 1 ATOM 5801 N N . MET A 1 719 ? 68.663 49.093 43.182 1.00 27.17 ? 755 MET A N 1 ATOM 5802 C CA . MET A 1 719 ? 68.130 47.741 43.103 1.00 25.94 ? 755 MET A CA 1 ATOM 5803 C C . MET A 1 719 ? 69.200 46.738 42.668 1.00 27.06 ? 755 MET A C 1 ATOM 5804 O O . MET A 1 719 ? 69.232 45.609 43.165 1.00 27.03 ? 755 MET A O 1 ATOM 5805 C CB . MET A 1 719 ? 66.916 47.687 42.172 1.00 25.23 ? 755 MET A CB 1 ATOM 5806 C CG . MET A 1 719 ? 65.763 48.571 42.606 1.00 25.06 ? 755 MET A CG 1 ATOM 5807 S SD . MET A 1 719 ? 64.234 48.224 41.707 1.00 28.14 ? 755 MET A SD 1 ATOM 5808 C CE . MET A 1 719 ? 64.759 48.523 40.030 1.00 24.26 ? 755 MET A CE 1 ATOM 5809 N N . SER A 1 720 ? 70.082 47.144 41.753 1.00 25.08 ? 756 SER A N 1 ATOM 5810 C CA . SER A 1 720 ? 71.153 46.249 41.307 1.00 27.64 ? 756 SER A CA 1 ATOM 5811 C C . SER A 1 720 ? 72.057 45.834 42.468 1.00 29.08 ? 756 SER A C 1 ATOM 5812 O O . SER A 1 720 ? 72.358 44.651 42.630 1.00 28.97 ? 756 SER A O 1 ATOM 5813 C CB . SER A 1 720 ? 71.975 46.887 40.181 1.00 27.37 ? 756 SER A CB 1 ATOM 5814 O OG . SER A 1 720 ? 71.157 47.119 39.051 1.00 29.44 ? 756 SER A OG 1 ATOM 5815 N N . HIS A 1 721 ? 72.475 46.803 43.286 1.00 29.30 ? 757 HIS A N 1 ATOM 5816 C CA . HIS A 1 721 ? 73.258 46.494 44.492 1.00 29.12 ? 757 HIS A CA 1 ATOM 5817 C C . HIS A 1 721 ? 72.501 45.518 45.380 1.00 30.61 ? 757 HIS A C 1 ATOM 5818 O O . HIS A 1 721 ? 73.084 44.580 45.924 1.00 32.49 ? 757 HIS A O 1 ATOM 5819 C CB . HIS A 1 721 ? 73.570 47.759 45.307 1.00 31.12 ? 757 HIS A CB 1 ATOM 5820 C CG . HIS A 1 721 ? 74.537 48.696 44.647 1.00 37.85 ? 757 HIS A CG 1 ATOM 5821 N ND1 . HIS A 1 721 ? 75.562 48.264 43.830 1.00 41.92 ? 757 HIS A ND1 1 ATOM 5822 C CD2 . HIS A 1 721 ? 74.640 50.048 44.694 1.00 40.27 ? 757 HIS A CD2 1 ATOM 5823 C CE1 . HIS A 1 721 ? 76.249 49.308 43.397 1.00 41.77 ? 757 HIS A CE1 1 ATOM 5824 N NE2 . HIS A 1 721 ? 75.712 50.402 43.907 1.00 43.56 ? 757 HIS A NE2 1 ATOM 5825 N N . PHE A 1 722 ? 71.204 45.739 45.546 1.00 27.16 ? 758 PHE A N 1 ATOM 5826 C CA . PHE A 1 722 ? 70.426 44.892 46.454 1.00 28.38 ? 758 PHE A CA 1 ATOM 5827 C C . PHE A 1 722 ? 70.364 43.441 45.962 1.00 33.54 ? 758 PHE A C 1 ATOM 5828 O O . PHE A 1 722 ? 70.592 42.518 46.739 1.00 33.33 ? 758 PHE A O 1 ATOM 5829 C CB . PHE A 1 722 ? 69.016 45.460 46.659 1.00 27.71 ? 758 PHE A CB 1 ATOM 5830 C CG . PHE A 1 722 ? 68.148 44.639 47.586 1.00 32.67 ? 758 PHE A CG 1 ATOM 5831 C CD1 . PHE A 1 722 ? 68.166 44.855 48.965 1.00 32.16 ? 758 PHE A CD1 1 ATOM 5832 C CD2 . PHE A 1 722 ? 67.302 43.666 47.077 1.00 30.30 ? 758 PHE A CD2 1 ATOM 5833 C CE1 . PHE A 1 722 ? 67.356 44.098 49.819 1.00 34.42 ? 758 PHE A CE1 1 ATOM 5834 C CE2 . PHE A 1 722 ? 66.485 42.925 47.909 1.00 30.44 ? 758 PHE A CE2 1 ATOM 5835 C CZ . PHE A 1 722 ? 66.500 43.135 49.282 1.00 30.62 ? 758 PHE A CZ 1 ATOM 5836 N N . ILE A 1 723 ? 70.060 43.241 44.678 1.00 30.02 ? 759 ILE A N 1 ATOM 5837 C CA . ILE A 1 723 ? 70.048 41.893 44.089 1.00 30.95 ? 759 ILE A CA 1 ATOM 5838 C C . ILE A 1 723 ? 71.433 41.246 44.134 1.00 35.15 ? 759 ILE A C 1 ATOM 5839 O O . ILE A 1 723 ? 71.571 40.067 44.476 1.00 34.31 ? 759 ILE A O 1 ATOM 5840 C CB . ILE A 1 723 ? 69.573 41.898 42.625 1.00 32.47 ? 759 ILE A CB 1 ATOM 5841 C CG1 . ILE A 1 723 ? 68.163 42.472 42.522 1.00 33.70 ? 759 ILE A CG1 1 ATOM 5842 C CG2 . ILE A 1 723 ? 69.607 40.471 42.044 1.00 33.89 ? 759 ILE A CG2 1 ATOM 5843 C CD1 . ILE A 1 723 ? 67.137 41.687 43.333 1.00 36.83 ? 759 ILE A CD1 1 ATOM 5844 N N . LYS A 1 724 ? 72.457 42.012 43.771 1.00 32.36 ? 760 LYS A N 1 ATOM 5845 C CA . LYS A 1 724 ? 73.822 41.494 43.795 1.00 38.65 ? 760 LYS A CA 1 ATOM 5846 C C . LYS A 1 724 ? 74.261 41.040 45.198 1.00 39.13 ? 760 LYS A C 1 ATOM 5847 O O . LYS A 1 724 ? 74.924 40.009 45.333 1.00 40.94 ? 760 LYS A O 1 ATOM 5848 C CB . LYS A 1 724 ? 74.803 42.502 43.187 1.00 38.54 ? 760 LYS A CB 1 ATOM 5849 C CG . LYS A 1 724 ? 74.811 42.492 41.657 1.00 38.69 ? 760 LYS A CG 1 ATOM 5850 C CD . LYS A 1 724 ? 76.096 43.103 41.090 1.00 44.70 ? 760 LYS A CD 1 ATOM 5851 C CE . LYS A 1 724 ? 76.011 44.619 41.031 1.00 45.67 ? 760 LYS A CE 1 ATOM 5852 N NZ . LYS A 1 724 ? 77.285 45.235 40.567 1.00 49.84 ? 760 LYS A NZ 1 ATOM 5853 N N . GLN A 1 725 ? 73.866 41.781 46.236 1.00 32.39 ? 761 GLN A N 1 ATOM 5854 C CA . GLN A 1 725 ? 74.137 41.362 47.624 1.00 38.03 ? 761 GLN A CA 1 ATOM 5855 C C . GLN A 1 725 ? 73.386 40.088 48.004 1.00 38.46 ? 761 GLN A C 1 ATOM 5856 O O . GLN A 1 725 ? 73.956 39.158 48.579 1.00 37.66 ? 761 GLN A O 1 ATOM 5857 C CB . GLN A 1 725 ? 73.771 42.471 48.620 1.00 41.42 ? 761 GLN A CB 1 ATOM 5858 C CG . GLN A 1 725 ? 74.644 43.713 48.508 1.00 46.08 ? 761 GLN A CG 1 ATOM 5859 N N . CYS A 1 726 ? 72.097 40.059 47.682 1.00 37.47 ? 762 CYS A N 1 ATOM 5860 C CA . CYS A 1 726 ? 71.242 38.925 48.008 1.00 37.70 ? 762 CYS A CA 1 ATOM 5861 C C . CYS A 1 726 ? 71.693 37.651 47.277 1.00 39.25 ? 762 CYS A C 1 ATOM 5862 O O . CYS A 1 726 ? 71.477 36.536 47.749 1.00 39.49 ? 762 CYS A O 1 ATOM 5863 C CB . CYS A 1 726 ? 69.780 39.282 47.692 1.00 40.49 ? 762 CYS A CB 1 ATOM 5864 S SG . CYS A 1 726 ? 68.559 37.918 47.684 1.00 54.95 ? 762 CYS A SG 1 ATOM 5865 N N . PHE A 1 727 ? 72.347 37.818 46.135 1.00 35.20 ? 763 PHE A N 1 ATOM 5866 C CA . PHE A 1 727 ? 72.799 36.667 45.357 1.00 37.63 ? 763 PHE A CA 1 ATOM 5867 C C . PHE A 1 727 ? 74.274 36.331 45.575 1.00 40.52 ? 763 PHE A C 1 ATOM 5868 O O . PHE A 1 727 ? 74.796 35.420 44.935 1.00 41.26 ? 763 PHE A O 1 ATOM 5869 C CB . PHE A 1 727 ? 72.528 36.884 43.863 1.00 36.38 ? 763 PHE A CB 1 ATOM 5870 C CG . PHE A 1 727 ? 71.082 36.674 43.467 1.00 36.52 ? 763 PHE A CG 1 ATOM 5871 C CD1 . PHE A 1 727 ? 70.178 36.133 44.359 1.00 32.93 ? 763 PHE A CD1 1 ATOM 5872 C CD2 . PHE A 1 727 ? 70.642 37.004 42.194 1.00 33.97 ? 763 PHE A CD2 1 ATOM 5873 C CE1 . PHE A 1 727 ? 68.862 35.923 44.004 1.00 34.29 ? 763 PHE A CE1 1 ATOM 5874 C CE2 . PHE A 1 727 ? 69.319 36.806 41.828 1.00 32.50 ? 763 PHE A CE2 1 ATOM 5875 C CZ . PHE A 1 727 ? 68.426 36.263 42.741 1.00 32.70 ? 763 PHE A CZ 1 ATOM 5876 N N . SER A 1 728 ? 74.936 37.071 46.467 1.00 45.02 ? 764 SER A N 1 ATOM 5877 C CA . SER A 1 728 ? 76.373 36.908 46.731 1.00 48.46 ? 764 SER A CA 1 ATOM 5878 C C . SER A 1 728 ? 77.197 37.077 45.458 1.00 58.49 ? 764 SER A C 1 ATOM 5879 O O . SER A 1 728 ? 78.132 36.300 45.207 1.00 63.75 ? 764 SER A O 1 ATOM 5880 C CB . SER A 1 728 ? 76.674 35.532 47.334 1.00 46.65 ? 764 SER A CB 1 ATOM 5881 O OG . SER A 1 728 ? 75.630 35.120 48.190 1.00 42.97 ? 764 SER A OG 1 ATOM 5882 N N . LEU A 1 729 ? 76.855 38.087 44.657 1.00 57.17 ? 765 LEU A N 1 ATOM 5883 C CA . LEU A 1 729 ? 77.498 38.279 43.359 1.00 62.34 ? 765 LEU A CA 1 ATOM 5884 C C . LEU A 1 729 ? 78.566 39.378 43.358 1.00 70.11 ? 765 LEU A C 1 ATOM 5885 O O . LEU A 1 729 ? 78.314 40.499 43.810 1.00 67.86 ? 765 LEU A O 1 ATOM 5886 C CB . LEU A 1 729 ? 76.450 38.553 42.274 1.00 58.13 ? 765 LEU A CB 1 ATOM 5887 C CG . LEU A 1 729 ? 75.533 37.391 41.886 1.00 53.50 ? 765 LEU A CG 1 ATOM 5888 C CD1 . LEU A 1 729 ? 74.570 37.848 40.801 1.00 43.06 ? 765 LEU A CD1 1 ATOM 5889 C CD2 . LEU A 1 729 ? 76.328 36.159 41.425 1.00 55.23 ? 765 LEU A CD2 1 ATOM 5890 N N . PRO A 1 730 ? 79.767 39.052 42.841 1.00 75.87 ? 766 PRO A N 1 ATOM 5891 C CA . PRO A 1 730 ? 80.878 40.007 42.728 1.00 79.00 ? 766 PRO A CA 1 ATOM 5892 C C . PRO A 1 730 ? 80.525 41.195 41.829 1.00 75.97 ? 766 PRO A C 1 ATOM 5893 O O . PRO A 1 730 ? 80.732 42.343 42.233 1.00 76.53 ? 766 PRO A O 1 ATOM 5894 C CB . PRO A 1 730 ? 81.993 39.171 42.084 1.00 80.16 ? 766 PRO A CB 1 ATOM 5895 C CG . PRO A 1 730 ? 81.644 37.746 42.411 1.00 76.83 ? 766 PRO A CG 1 ATOM 5896 C CD . PRO A 1 730 ? 80.146 37.704 42.374 1.00 70.77 ? 766 PRO A CD 1 ATOM 5897 N N . ARG B 1 4 ? 80.325 35.549 82.579 1.00 59.29 ? 40 ARG B N 1 ATOM 5898 C CA . ARG B 1 4 ? 79.485 36.746 82.604 1.00 55.41 ? 40 ARG B CA 1 ATOM 5899 C C . ARG B 1 4 ? 78.917 37.067 81.220 1.00 54.39 ? 40 ARG B C 1 ATOM 5900 O O . ARG B 1 4 ? 79.614 36.980 80.209 1.00 51.95 ? 40 ARG B O 1 ATOM 5901 C CB . ARG B 1 4 ? 80.264 37.958 83.134 1.00 52.15 ? 40 ARG B CB 1 ATOM 5902 C CG . ARG B 1 4 ? 80.526 37.957 84.639 1.00 54.09 ? 40 ARG B CG 1 ATOM 5903 C CD . ARG B 1 4 ? 81.329 39.188 85.050 1.00 51.59 ? 40 ARG B CD 1 ATOM 5904 N N . LYS B 1 5 ? 77.643 37.441 81.184 1.00 52.85 ? 41 LYS B N 1 ATOM 5905 C CA . LYS B 1 5 ? 77.027 37.885 79.947 1.00 49.15 ? 41 LYS B CA 1 ATOM 5906 C C . LYS B 1 5 ? 77.373 39.348 79.688 1.00 44.80 ? 41 LYS B C 1 ATOM 5907 O O . LYS B 1 5 ? 77.950 40.042 80.531 1.00 42.86 ? 41 LYS B O 1 ATOM 5908 C CB . LYS B 1 5 ? 75.506 37.696 79.987 1.00 48.37 ? 41 LYS B CB 1 ATOM 5909 C CG . LYS B 1 5 ? 74.812 38.362 81.172 1.00 45.41 ? 41 LYS B CG 1 ATOM 5910 N N . THR B 1 6 ? 77.000 39.809 78.510 1.00 40.60 ? 42 THR B N 1 ATOM 5911 C CA . THR B 1 6 ? 77.312 41.150 78.074 1.00 37.25 ? 42 THR B CA 1 ATOM 5912 C C . THR B 1 6 ? 76.018 41.993 78.075 1.00 36.33 ? 42 THR B C 1 ATOM 5913 O O . THR B 1 6 ? 74.927 41.459 78.290 1.00 37.01 ? 42 THR B O 1 ATOM 5914 C CB . THR B 1 6 ? 77.938 41.065 76.685 1.00 41.57 ? 42 THR B CB 1 ATOM 5915 O OG1 . THR B 1 6 ? 78.423 42.350 76.285 1.00 50.70 ? 42 THR B OG1 1 ATOM 5916 C CG2 . THR B 1 6 ? 76.913 40.556 75.684 1.00 31.18 ? 42 THR B CG2 1 ATOM 5917 N N . TYR B 1 7 ? 76.131 43.303 77.881 1.00 35.27 ? 43 TYR B N 1 ATOM 5918 C CA . TYR B 1 7 ? 74.942 44.162 77.824 1.00 32.01 ? 43 TYR B CA 1 ATOM 5919 C C . TYR B 1 7 ? 74.460 44.205 76.378 1.00 34.34 ? 43 TYR B C 1 ATOM 5920 O O . TYR B 1 7 ? 75.080 44.851 75.531 1.00 33.97 ? 43 TYR B O 1 ATOM 5921 C CB . TYR B 1 7 ? 75.267 45.568 78.329 1.00 33.00 ? 43 TYR B CB 1 ATOM 5922 C CG . TYR B 1 7 ? 74.078 46.499 78.400 1.00 33.57 ? 43 TYR B CG 1 ATOM 5923 C CD1 . TYR B 1 7 ? 73.265 46.537 79.521 1.00 31.44 ? 43 TYR B CD1 1 ATOM 5924 C CD2 . TYR B 1 7 ? 73.776 47.348 77.347 1.00 32.61 ? 43 TYR B CD2 1 ATOM 5925 C CE1 . TYR B 1 7 ? 72.178 47.391 79.598 1.00 29.08 ? 43 TYR B CE1 1 ATOM 5926 C CE2 . TYR B 1 7 ? 72.690 48.205 77.413 1.00 34.33 ? 43 TYR B CE2 1 ATOM 5927 C CZ . TYR B 1 7 ? 71.900 48.228 78.544 1.00 34.19 ? 43 TYR B CZ 1 ATOM 5928 O OH . TYR B 1 7 ? 70.820 49.076 78.595 1.00 33.48 ? 43 TYR B OH 1 ATOM 5929 N N . THR B 1 8 ? 73.360 43.504 76.101 1.00 34.58 ? 44 THR B N 1 ATOM 5930 C CA . THR B 1 8 ? 72.921 43.243 74.723 1.00 31.11 ? 44 THR B CA 1 ATOM 5931 C C . THR B 1 8 ? 71.936 44.283 74.188 1.00 32.03 ? 44 THR B C 1 ATOM 5932 O O . THR B 1 8 ? 71.406 45.099 74.946 1.00 30.50 ? 44 THR B O 1 ATOM 5933 C CB . THR B 1 8 ? 72.243 41.874 74.632 1.00 31.64 ? 44 THR B CB 1 ATOM 5934 O OG1 . THR B 1 8 ? 70.998 41.930 75.327 1.00 30.78 ? 44 THR B OG1 1 ATOM 5935 C CG2 . THR B 1 8 ? 73.126 40.794 75.258 1.00 37.46 ? 44 THR B CG2 1 ATOM 5936 N N . LEU B 1 9 ? 71.677 44.251 72.882 1.00 34.40 ? 45 LEU B N 1 ATOM 5937 C CA . LEU B 1 9 ? 70.736 45.205 72.295 1.00 31.64 ? 45 LEU B CA 1 ATOM 5938 C C . LEU B 1 9 ? 69.367 45.053 72.950 1.00 33.51 ? 45 LEU B C 1 ATOM 5939 O O . LEU B 1 9 ? 68.717 46.045 73.284 1.00 32.40 ? 45 LEU B O 1 ATOM 5940 C CB . LEU B 1 9 ? 70.634 45.035 70.774 1.00 32.89 ? 45 LEU B CB 1 ATOM 5941 C CG . LEU B 1 9 ? 69.724 46.041 70.045 1.00 31.59 ? 45 LEU B CG 1 ATOM 5942 C CD1 . LEU B 1 9 ? 70.094 47.486 70.382 1.00 33.91 ? 45 LEU B CD1 1 ATOM 5943 C CD2 . LEU B 1 9 ? 69.747 45.829 68.536 1.00 33.19 ? 45 LEU B CD2 1 ATOM 5944 N N . THR B 1 10 ? 68.943 43.808 73.162 1.00 35.59 ? 46 THR B N 1 ATOM 5945 C CA . THR B 1 10 ? 67.657 43.539 73.813 1.00 34.89 ? 46 THR B CA 1 ATOM 5946 C C . THR B 1 10 ? 67.585 44.075 75.238 1.00 34.52 ? 46 THR B C 1 ATOM 5947 O O . THR B 1 10 ? 66.521 44.487 75.697 1.00 33.23 ? 46 THR B O 1 ATOM 5948 C CB . THR B 1 10 ? 67.342 42.050 73.845 1.00 38.34 ? 46 THR B CB 1 ATOM 5949 O OG1 . THR B 1 10 ? 67.300 41.567 72.496 1.00 48.31 ? 46 THR B OG1 1 ATOM 5950 C CG2 . THR B 1 10 ? 66.000 41.813 74.502 1.00 40.54 ? 46 THR B CG2 1 ATOM 5951 N N . ASP B 1 11 ? 68.717 44.066 75.934 1.00 34.69 ? 47 ASP B N 1 ATOM 5952 C CA . ASP B 1 11 ? 68.768 44.608 77.289 1.00 34.52 ? 47 ASP B CA 1 ATOM 5953 C C . ASP B 1 11 ? 68.449 46.093 77.269 1.00 33.51 ? 47 ASP B C 1 ATOM 5954 O O . ASP B 1 11 ? 67.648 46.585 78.078 1.00 35.86 ? 47 ASP B O 1 ATOM 5955 C CB . ASP B 1 11 ? 70.137 44.364 77.909 1.00 29.46 ? 47 ASP B CB 1 ATOM 5956 C CG . ASP B 1 11 ? 70.325 42.924 78.346 1.00 33.50 ? 47 ASP B CG 1 ATOM 5957 O OD1 . ASP B 1 11 ? 69.315 42.275 78.705 1.00 39.24 ? 47 ASP B OD1 1 ATOM 5958 O OD2 . ASP B 1 11 ? 71.477 42.438 78.322 1.00 37.62 ? 47 ASP B OD2 1 ATOM 5959 N N . TYR B 1 12 ? 69.088 46.800 76.340 1.00 28.84 ? 48 TYR B N 1 ATOM 5960 C CA . TYR B 1 12 ? 68.825 48.218 76.122 1.00 29.53 ? 48 TYR B CA 1 ATOM 5961 C C . TYR B 1 12 ? 67.356 48.463 75.763 1.00 30.80 ? 48 TYR B C 1 ATOM 5962 O O . TYR B 1 12 ? 66.681 49.289 76.384 1.00 32.82 ? 48 TYR B O 1 ATOM 5963 C CB . TYR B 1 12 ? 69.743 48.781 75.025 1.00 27.28 ? 48 TYR B CB 1 ATOM 5964 C CG . TYR B 1 12 ? 69.355 50.180 74.581 1.00 30.19 ? 48 TYR B CG 1 ATOM 5965 C CD1 . TYR B 1 12 ? 69.219 51.217 75.509 1.00 28.31 ? 48 TYR B CD1 1 ATOM 5966 C CD2 . TYR B 1 12 ? 69.116 50.463 73.244 1.00 27.26 ? 48 TYR B CD2 1 ATOM 5967 C CE1 . TYR B 1 12 ? 68.856 52.505 75.109 1.00 29.05 ? 48 TYR B CE1 1 ATOM 5968 C CE2 . TYR B 1 12 ? 68.751 51.750 72.831 1.00 25.98 ? 48 TYR B CE2 1 ATOM 5969 C CZ . TYR B 1 12 ? 68.627 52.761 73.766 1.00 32.07 ? 48 TYR B CZ 1 ATOM 5970 O OH . TYR B 1 12 ? 68.263 54.026 73.350 1.00 32.64 ? 48 TYR B OH 1 ATOM 5971 N N . LEU B 1 13 ? 66.859 47.728 74.775 1.00 32.05 ? 49 LEU B N 1 ATOM 5972 C CA . LEU B 1 13 ? 65.538 47.999 74.204 1.00 32.14 ? 49 LEU B CA 1 ATOM 5973 C C . LEU B 1 13 ? 64.402 47.580 75.131 1.00 34.92 ? 49 LEU B C 1 ATOM 5974 O O . LEU B 1 13 ? 63.351 48.220 75.163 1.00 36.74 ? 49 LEU B O 1 ATOM 5975 C CB . LEU B 1 13 ? 65.386 47.309 72.841 1.00 30.63 ? 49 LEU B CB 1 ATOM 5976 C CG . LEU B 1 13 ? 66.320 47.738 71.711 1.00 31.56 ? 49 LEU B CG 1 ATOM 5977 C CD1 . LEU B 1 13 ? 66.070 46.910 70.442 1.00 30.00 ? 49 LEU B CD1 1 ATOM 5978 C CD2 . LEU B 1 13 ? 66.175 49.231 71.426 1.00 29.98 ? 49 LEU B CD2 1 ATOM 5979 N N . LYS B 1 14 ? 64.611 46.508 75.890 1.00 37.27 ? 50 LYS B N 1 ATOM 5980 C CA . LYS B 1 14 ? 63.596 46.050 76.837 1.00 36.32 ? 50 LYS B CA 1 ATOM 5981 C C . LYS B 1 14 ? 63.759 46.657 78.240 1.00 40.07 ? 50 LYS B C 1 ATOM 5982 O O . LYS B 1 14 ? 62.962 46.381 79.126 1.00 38.44 ? 50 LYS B O 1 ATOM 5983 C CB . LYS B 1 14 ? 63.581 44.522 76.932 1.00 39.99 ? 50 LYS B CB 1 ATOM 5984 C CG . LYS B 1 14 ? 63.271 43.807 75.625 1.00 40.90 ? 50 LYS B CG 1 ATOM 5985 C CD . LYS B 1 14 ? 61.917 44.227 75.062 1.00 46.28 ? 50 LYS B CD 1 ATOM 5986 C CE . LYS B 1 14 ? 61.619 43.478 73.776 1.00 51.50 ? 50 LYS B CE 1 ATOM 5987 N NZ . LYS B 1 14 ? 60.240 43.735 73.290 1.00 58.76 ? 50 LYS B NZ 1 ATOM 5988 N N . ASN B 1 15 ? 64.791 47.468 78.442 1.00 36.86 ? 51 ASN B N 1 ATOM 5989 C CA . ASN B 1 15 ? 64.978 48.123 79.724 1.00 39.91 ? 51 ASN B CA 1 ATOM 5990 C C . ASN B 1 15 ? 65.194 47.101 80.836 1.00 41.47 ? 51 ASN B C 1 ATOM 5991 O O . ASN B 1 15 ? 64.645 47.236 81.925 1.00 40.33 ? 51 ASN B O 1 ATOM 5992 C CB . ASN B 1 15 ? 63.758 48.988 80.049 1.00 41.89 ? 51 ASN B CB 1 ATOM 5993 C CG . ASN B 1 15 ? 64.127 50.417 80.372 1.00 53.52 ? 51 ASN B CG 1 ATOM 5994 O OD1 . ASN B 1 15 ? 64.420 50.756 81.528 1.00 51.26 ? 51 ASN B OD1 1 ATOM 5995 N ND2 . ASN B 1 15 ? 64.126 51.270 79.347 1.00 52.22 ? 51 ASN B ND2 1 ATOM 5996 N N . THR B 1 16 ? 65.989 46.076 80.552 1.00 37.08 ? 52 THR B N 1 ATOM 5997 C CA . THR B 1 16 ? 66.239 45.014 81.515 1.00 38.72 ? 52 THR B CA 1 ATOM 5998 C C . THR B 1 16 ? 66.918 45.500 82.811 1.00 41.91 ? 52 THR B C 1 ATOM 5999 O O . THR B 1 16 ? 66.585 45.045 83.901 1.00 40.93 ? 52 THR B O 1 ATOM 6000 C CB . THR B 1 16 ? 67.045 43.889 80.866 1.00 38.42 ? 52 THR B CB 1 ATOM 6001 O OG1 . THR B 1 16 ? 66.262 43.317 79.813 1.00 40.92 ? 52 THR B OG1 1 ATOM 6002 C CG2 . THR B 1 16 ? 67.370 42.809 81.887 1.00 40.38 ? 52 THR B CG2 1 ATOM 6003 N N . TYR B 1 17 ? 67.864 46.424 82.679 1.00 39.42 ? 53 TYR B N 1 ATOM 6004 C CA . TYR B 1 17 ? 68.564 46.992 83.821 1.00 36.68 ? 53 TYR B CA 1 ATOM 6005 C C . TYR B 1 17 ? 68.097 48.426 84.086 1.00 39.32 ? 53 TYR B C 1 ATOM 6006 O O . TYR B 1 17 ? 68.504 49.355 83.391 1.00 39.87 ? 53 TYR B O 1 ATOM 6007 C CB . TYR B 1 17 ? 70.074 46.924 83.573 1.00 36.59 ? 53 TYR B CB 1 ATOM 6008 C CG . TYR B 1 17 ? 70.556 45.506 83.302 1.00 39.87 ? 53 TYR B CG 1 ATOM 6009 C CD1 . TYR B 1 17 ? 70.787 44.620 84.347 1.00 37.86 ? 53 TYR B CD1 1 ATOM 6010 C CD2 . TYR B 1 17 ? 70.756 45.049 82.010 1.00 36.99 ? 53 TYR B CD2 1 ATOM 6011 C CE1 . TYR B 1 17 ? 71.210 43.331 84.113 1.00 38.86 ? 53 TYR B CE1 1 ATOM 6012 C CE2 . TYR B 1 17 ? 71.187 43.748 81.766 1.00 37.64 ? 53 TYR B CE2 1 ATOM 6013 C CZ . TYR B 1 17 ? 71.408 42.898 82.822 1.00 40.31 ? 53 TYR B CZ 1 ATOM 6014 O OH . TYR B 1 17 ? 71.830 41.610 82.599 1.00 41.36 ? 53 TYR B OH 1 ATOM 6015 N N . ARG B 1 18 ? 67.231 48.604 85.082 1.00 38.66 ? 54 ARG B N 1 ATOM 6016 C CA . ARG B 1 18 ? 66.560 49.893 85.280 1.00 41.74 ? 54 ARG B CA 1 ATOM 6017 C C . ARG B 1 18 ? 67.162 50.735 86.406 1.00 38.13 ? 54 ARG B C 1 ATOM 6018 O O . ARG B 1 18 ? 67.459 50.222 87.486 1.00 35.25 ? 54 ARG B O 1 ATOM 6019 C CB . ARG B 1 18 ? 65.061 49.697 85.543 1.00 45.80 ? 54 ARG B CB 1 ATOM 6020 C CG . ARG B 1 18 ? 64.253 49.201 84.346 1.00 49.75 ? 54 ARG B CG 1 ATOM 6021 C CD . ARG B 1 18 ? 62.817 48.846 84.750 1.00 62.22 ? 54 ARG B CD 1 ATOM 6022 N NE . ARG B 1 18 ? 62.032 48.315 83.631 1.00 64.35 ? 54 ARG B NE 1 ATOM 6023 C CZ . ARG B 1 18 ? 61.293 49.060 82.811 1.00 55.14 ? 54 ARG B CZ 1 ATOM 6024 N N . LEU B 1 19 ? 67.337 52.027 86.142 1.00 33.38 ? 55 LEU B N 1 ATOM 6025 C CA . LEU B 1 19 ? 67.770 52.969 87.164 1.00 35.76 ? 55 LEU B CA 1 ATOM 6026 C C . LEU B 1 19 ? 66.576 53.362 88.020 1.00 41.13 ? 55 LEU B C 1 ATOM 6027 O O . LEU B 1 19 ? 65.533 53.763 87.501 1.00 41.86 ? 55 LEU B O 1 ATOM 6028 C CB . LEU B 1 19 ? 68.369 54.230 86.535 1.00 34.11 ? 55 LEU B CB 1 ATOM 6029 C CG . LEU B 1 19 ? 69.658 54.072 85.733 1.00 39.50 ? 55 LEU B CG 1 ATOM 6030 C CD1 . LEU B 1 19 ? 70.017 55.356 85.003 1.00 39.17 ? 55 LEU B CD1 1 ATOM 6031 C CD2 . LEU B 1 19 ? 70.779 53.655 86.643 1.00 37.93 ? 55 LEU B CD2 1 ATOM 6032 N N . LYS B 1 20 ? 66.724 53.253 89.333 1.00 37.78 ? 56 LYS B N 1 ATOM 6033 C CA . LYS B 1 20 ? 65.683 53.727 90.240 1.00 39.81 ? 56 LYS B CA 1 ATOM 6034 C C . LYS B 1 20 ? 65.867 55.209 90.501 1.00 35.75 ? 56 LYS B C 1 ATOM 6035 O O . LYS B 1 20 ? 66.988 55.717 90.482 1.00 35.63 ? 56 LYS B O 1 ATOM 6036 C CB . LYS B 1 20 ? 65.690 52.953 91.557 1.00 34.86 ? 56 LYS B CB 1 ATOM 6037 C CG . LYS B 1 20 ? 64.982 51.614 91.489 1.00 39.84 ? 56 LYS B CG 1 ATOM 6038 C CD . LYS B 1 20 ? 64.715 51.094 92.903 1.00 48.68 ? 56 LYS B CD 1 ATOM 6039 C CE . LYS B 1 20 ? 64.443 49.591 92.934 1.00 53.32 ? 56 LYS B CE 1 ATOM 6040 N NZ . LYS B 1 20 ? 64.623 49.060 94.332 1.00 51.08 ? 56 LYS B NZ 1 ATOM 6041 N N . LEU B 1 21 ? 64.757 55.902 90.719 1.00 38.53 ? 57 LEU B N 1 ATOM 6042 C CA . LEU B 1 21 ? 64.793 57.335 90.980 1.00 39.40 ? 57 LEU B CA 1 ATOM 6043 C C . LEU B 1 21 ? 64.209 57.588 92.365 1.00 38.53 ? 57 LEU B C 1 ATOM 6044 O O . LEU B 1 21 ? 63.710 56.662 93.019 1.00 38.21 ? 57 LEU B O 1 ATOM 6045 C CB . LEU B 1 21 ? 63.968 58.090 89.928 1.00 42.99 ? 57 LEU B CB 1 ATOM 6046 C CG . LEU B 1 21 ? 63.924 57.574 88.485 1.00 46.02 ? 57 LEU B CG 1 ATOM 6047 C CD1 . LEU B 1 21 ? 62.843 58.311 87.697 1.00 52.17 ? 57 LEU B CD1 1 ATOM 6048 C CD2 . LEU B 1 21 ? 65.280 57.672 87.782 1.00 45.46 ? 57 LEU B CD2 1 ATOM 6049 N N . TYR B 1 22 ? 64.278 58.833 92.822 1.00 34.43 ? 58 TYR B N 1 ATOM 6050 C CA . TYR B 1 22 ? 63.530 59.229 94.019 1.00 33.44 ? 58 TYR B CA 1 ATOM 6051 C C . TYR B 1 22 ? 62.944 60.599 93.742 1.00 34.40 ? 58 TYR B C 1 ATOM 6052 O O . TYR B 1 22 ? 63.563 61.621 94.010 1.00 30.30 ? 58 TYR B O 1 ATOM 6053 C CB . TYR B 1 22 ? 64.409 59.263 95.272 1.00 29.71 ? 58 TYR B CB 1 ATOM 6054 C CG . TYR B 1 22 ? 63.625 59.247 96.567 1.00 30.63 ? 58 TYR B CG 1 ATOM 6055 C CD1 . TYR B 1 22 ? 63.149 60.419 97.135 1.00 31.23 ? 58 TYR B CD1 1 ATOM 6056 C CD2 . TYR B 1 22 ? 63.371 58.045 97.227 1.00 32.10 ? 58 TYR B CD2 1 ATOM 6057 C CE1 . TYR B 1 22 ? 62.430 60.398 98.323 1.00 32.33 ? 58 TYR B CE1 1 ATOM 6058 C CE2 . TYR B 1 22 ? 62.663 58.012 98.402 1.00 32.67 ? 58 TYR B CE2 1 ATOM 6059 C CZ . TYR B 1 22 ? 62.196 59.189 98.954 1.00 33.39 ? 58 TYR B CZ 1 ATOM 6060 O OH . TYR B 1 22 ? 61.502 59.144 100.136 1.00 31.98 ? 58 TYR B OH 1 ATOM 6061 N N . SER B 1 23 ? 61.753 60.605 93.165 1.00 33.70 ? 59 SER B N 1 ATOM 6062 C CA . SER B 1 23 ? 61.135 61.832 92.729 1.00 31.79 ? 59 SER B CA 1 ATOM 6063 C C . SER B 1 23 ? 60.186 62.319 93.815 1.00 31.22 ? 59 SER B C 1 ATOM 6064 O O . SER B 1 23 ? 59.151 61.717 94.078 1.00 29.65 ? 59 SER B O 1 ATOM 6065 C CB . SER B 1 23 ? 60.397 61.583 91.407 1.00 34.80 ? 59 SER B CB 1 ATOM 6066 O OG . SER B 1 23 ? 59.482 62.625 91.122 1.00 44.96 ? 59 SER B OG 1 ATOM 6067 N N . LEU B 1 24 ? 60.549 63.413 94.461 1.00 29.15 ? 60 LEU B N 1 ATOM 6068 C CA . LEU B 1 24 ? 59.721 63.923 95.542 1.00 33.44 ? 60 LEU B CA 1 ATOM 6069 C C . LEU B 1 24 ? 59.208 65.307 95.202 1.00 34.52 ? 60 LEU B C 1 ATOM 6070 O O . LEU B 1 24 ? 59.802 66.021 94.383 1.00 29.57 ? 60 LEU B O 1 ATOM 6071 C CB . LEU B 1 24 ? 60.519 63.957 96.851 1.00 28.88 ? 60 LEU B CB 1 ATOM 6072 C CG . LEU B 1 24 ? 61.867 64.685 96.873 1.00 29.29 ? 60 LEU B CG 1 ATOM 6073 C CD1 . LEU B 1 24 ? 61.654 66.183 96.918 1.00 30.41 ? 60 LEU B CD1 1 ATOM 6074 C CD2 . LEU B 1 24 ? 62.664 64.232 98.108 1.00 28.65 ? 60 LEU B CD2 1 ATOM 6075 N N . ARG B 1 25 ? 58.106 65.693 95.827 1.00 32.10 ? 61 ARG B N 1 ATOM 6076 C CA . ARG B 1 25 ? 57.650 67.064 95.692 1.00 33.18 ? 61 ARG B CA 1 ATOM 6077 C C . ARG B 1 25 ? 57.554 67.713 97.049 1.00 32.42 ? 61 ARG B C 1 ATOM 6078 O O . ARG B 1 25 ? 56.769 67.281 97.894 1.00 32.21 ? 61 ARG B O 1 ATOM 6079 C CB . ARG B 1 25 ? 56.298 67.154 94.993 1.00 36.83 ? 61 ARG B CB 1 ATOM 6080 C CG . ARG B 1 25 ? 55.792 68.600 94.954 1.00 44.30 ? 61 ARG B CG 1 ATOM 6081 C CD . ARG B 1 25 ? 54.767 68.845 93.852 1.00 51.15 ? 61 ARG B CD 1 ATOM 6082 N NE . ARG B 1 25 ? 53.389 68.719 94.328 1.00 56.89 ? 61 ARG B NE 1 ATOM 6083 C CZ . ARG B 1 25 ? 52.721 69.674 94.979 1.00 53.85 ? 61 ARG B CZ 1 ATOM 6084 N NH1 . ARG B 1 25 ? 53.303 70.840 95.251 1.00 51.76 ? 61 ARG B NH1 1 ATOM 6085 N NH2 . ARG B 1 25 ? 51.464 69.459 95.356 1.00 45.76 ? 61 ARG B NH2 1 ATOM 6086 N N . TRP B 1 26 ? 58.342 68.759 97.256 1.00 28.68 ? 62 TRP B N 1 ATOM 6087 C CA . TRP B 1 26 ? 58.259 69.513 98.495 1.00 30.94 ? 62 TRP B CA 1 ATOM 6088 C C . TRP B 1 26 ? 56.921 70.213 98.622 1.00 32.65 ? 62 TRP B C 1 ATOM 6089 O O . TRP B 1 26 ? 56.468 70.896 97.712 1.00 34.09 ? 62 TRP B O 1 ATOM 6090 C CB . TRP B 1 26 ? 59.388 70.530 98.593 1.00 28.14 ? 62 TRP B CB 1 ATOM 6091 C CG . TRP B 1 26 ? 60.737 69.902 98.803 1.00 30.79 ? 62 TRP B CG 1 ATOM 6092 C CD1 . TRP B 1 26 ? 61.749 69.801 97.886 1.00 27.48 ? 62 TRP B CD1 1 ATOM 6093 C CD2 . TRP B 1 26 ? 61.219 69.283 100.005 1.00 29.18 ? 62 TRP B CD2 1 ATOM 6094 N NE1 . TRP B 1 26 ? 62.833 69.170 98.449 1.00 26.19 ? 62 TRP B NE1 1 ATOM 6095 C CE2 . TRP B 1 26 ? 62.531 68.835 99.745 1.00 28.51 ? 62 TRP B CE2 1 ATOM 6096 C CE3 . TRP B 1 26 ? 60.669 69.065 101.278 1.00 29.31 ? 62 TRP B CE3 1 ATOM 6097 C CZ2 . TRP B 1 26 ? 63.302 68.189 100.708 1.00 30.22 ? 62 TRP B CZ2 1 ATOM 6098 C CZ3 . TRP B 1 26 ? 61.434 68.427 102.229 1.00 27.52 ? 62 TRP B CZ3 1 ATOM 6099 C CH2 . TRP B 1 26 ? 62.736 67.994 101.945 1.00 28.59 ? 62 TRP B CH2 1 ATOM 6100 N N . ILE B 1 27 ? 56.311 70.060 99.783 1.00 33.21 ? 63 ILE B N 1 ATOM 6101 C CA . ILE B 1 27 ? 54.966 70.539 100.037 1.00 32.68 ? 63 ILE B CA 1 ATOM 6102 C C . ILE B 1 27 ? 54.995 71.688 101.052 1.00 34.67 ? 63 ILE B C 1 ATOM 6103 O O . ILE B 1 27 ? 54.018 72.416 101.234 1.00 35.27 ? 63 ILE B O 1 ATOM 6104 C CB . ILE B 1 27 ? 54.107 69.354 100.549 1.00 39.75 ? 63 ILE B CB 1 ATOM 6105 C CG1 . ILE B 1 27 ? 52.806 69.263 99.772 1.00 45.80 ? 63 ILE B CG1 1 ATOM 6106 C CG2 . ILE B 1 27 ? 53.936 69.350 102.062 1.00 32.71 ? 63 ILE B CG2 1 ATOM 6107 C CD1 . ILE B 1 27 ? 53.035 68.721 98.417 1.00 40.43 ? 63 ILE B CD1 1 ATOM 6108 N N . SER B 1 28 ? 56.136 71.851 101.709 1.00 32.71 ? 64 SER B N 1 ATOM 6109 C CA . SER B 1 28 ? 56.294 72.891 102.710 1.00 29.41 ? 64 SER B CA 1 ATOM 6110 C C . SER B 1 28 ? 57.766 73.008 103.042 1.00 31.58 ? 64 SER B C 1 ATOM 6111 O O . SER B 1 28 ? 58.625 72.480 102.340 1.00 32.32 ? 64 SER B O 1 ATOM 6112 C CB . SER B 1 28 ? 55.509 72.549 103.981 1.00 35.88 ? 64 SER B CB 1 ATOM 6113 O OG . SER B 1 28 ? 56.219 71.609 104.781 1.00 35.11 ? 64 SER B OG 1 ATOM 6114 N N . ASP B 1 29 ? 58.066 73.696 104.128 1.00 34.71 ? 65 ASP B N 1 ATOM 6115 C CA . ASP B 1 29 ? 59.444 73.844 104.521 1.00 33.69 ? 65 ASP B CA 1 ATOM 6116 C C . ASP B 1 29 ? 60.019 72.538 105.084 1.00 34.20 ? 65 ASP B C 1 ATOM 6117 O O . ASP B 1 29 ? 61.239 72.395 105.198 1.00 36.25 ? 65 ASP B O 1 ATOM 6118 C CB . ASP B 1 29 ? 59.596 74.980 105.528 1.00 37.52 ? 65 ASP B CB 1 ATOM 6119 C CG . ASP B 1 29 ? 61.045 75.332 105.769 1.00 47.81 ? 65 ASP B CG 1 ATOM 6120 O OD1 . ASP B 1 29 ? 61.849 75.101 104.836 1.00 45.79 ? 65 ASP B OD1 1 ATOM 6121 O OD2 . ASP B 1 29 ? 61.387 75.815 106.874 1.00 56.02 ? 65 ASP B OD2 1 ATOM 6122 N N . HIS B 1 30 ? 59.163 71.575 105.416 1.00 29.06 ? 66 HIS B N 1 ATOM 6123 C CA . HIS B 1 30 ? 59.670 70.386 106.111 1.00 35.01 ? 66 HIS B CA 1 ATOM 6124 C C . HIS B 1 30 ? 59.080 69.031 105.710 1.00 34.23 ? 66 HIS B C 1 ATOM 6125 O O . HIS B 1 30 ? 59.479 68.014 106.264 1.00 32.68 ? 66 HIS B O 1 ATOM 6126 C CB . HIS B 1 30 ? 59.541 70.560 107.627 1.00 36.84 ? 66 HIS B CB 1 ATOM 6127 C CG . HIS B 1 30 ? 58.138 70.446 108.126 1.00 40.45 ? 66 HIS B CG 1 ATOM 6128 N ND1 . HIS B 1 30 ? 57.781 69.608 109.163 1.00 48.84 ? 66 HIS B ND1 1 ATOM 6129 C CD2 . HIS B 1 30 ? 56.998 71.065 107.733 1.00 42.98 ? 66 HIS B CD2 1 ATOM 6130 C CE1 . HIS B 1 30 ? 56.482 69.717 109.389 1.00 48.48 ? 66 HIS B CE1 1 ATOM 6131 N NE2 . HIS B 1 30 ? 55.983 70.596 108.535 1.00 48.34 ? 66 HIS B NE2 1 ATOM 6132 N N . GLU B 1 31 ? 58.146 69.016 104.763 1.00 31.42 ? 67 GLU B N 1 ATOM 6133 C CA . GLU B 1 31 ? 57.501 67.781 104.319 1.00 27.85 ? 67 GLU B CA 1 ATOM 6134 C C . GLU B 1 31 ? 57.513 67.658 102.806 1.00 30.32 ? 67 GLU B C 1 ATOM 6135 O O . GLU B 1 31 ? 57.492 68.667 102.096 1.00 29.26 ? 67 GLU B O 1 ATOM 6136 C CB . GLU B 1 31 ? 56.042 67.729 104.785 1.00 32.86 ? 67 GLU B CB 1 ATOM 6137 C CG . GLU B 1 31 ? 55.853 67.565 106.277 1.00 38.26 ? 67 GLU B CG 1 ATOM 6138 C CD . GLU B 1 31 ? 54.400 67.337 106.680 1.00 45.90 ? 67 GLU B CD 1 ATOM 6139 O OE1 . GLU B 1 31 ? 53.489 67.898 106.017 1.00 40.85 ? 67 GLU B OE1 1 ATOM 6140 O OE2 . GLU B 1 31 ? 54.172 66.584 107.665 1.00 46.02 ? 67 GLU B OE2 1 ATOM 6141 N N . TYR B 1 32 ? 57.519 66.421 102.312 1.00 30.61 ? 68 TYR B N 1 ATOM 6142 C CA . TYR B 1 32 ? 57.396 66.163 100.878 1.00 30.66 ? 68 TYR B CA 1 ATOM 6143 C C . TYR B 1 32 ? 56.474 64.995 100.539 1.00 34.31 ? 68 TYR B C 1 ATOM 6144 O O . TYR B 1 32 ? 56.231 64.106 101.373 1.00 34.41 ? 68 TYR B O 1 ATOM 6145 C CB . TYR B 1 32 ? 58.766 65.959 100.225 1.00 30.44 ? 68 TYR B CB 1 ATOM 6146 C CG . TYR B 1 32 ? 59.550 64.725 100.651 1.00 31.48 ? 68 TYR B CG 1 ATOM 6147 C CD1 . TYR B 1 32 ? 59.249 63.458 100.140 1.00 29.62 ? 68 TYR B CD1 1 ATOM 6148 C CD2 . TYR B 1 32 ? 60.638 64.839 101.501 1.00 29.42 ? 68 TYR B CD2 1 ATOM 6149 C CE1 . TYR B 1 32 ? 60.002 62.342 100.506 1.00 28.10 ? 68 TYR B CE1 1 ATOM 6150 C CE2 . TYR B 1 32 ? 61.389 63.734 101.874 1.00 30.39 ? 68 TYR B CE2 1 ATOM 6151 C CZ . TYR B 1 32 ? 61.074 62.491 101.376 1.00 33.41 ? 68 TYR B CZ 1 ATOM 6152 O OH . TYR B 1 32 ? 61.843 61.406 101.758 1.00 29.77 ? 68 TYR B OH 1 ATOM 6153 N N . LEU B 1 33 ? 55.939 65.025 99.321 1.00 28.42 ? 69 LEU B N 1 ATOM 6154 C CA . LEU B 1 33 ? 55.126 63.939 98.797 1.00 29.18 ? 69 LEU B CA 1 ATOM 6155 C C . LEU B 1 33 ? 56.025 62.992 98.033 1.00 30.79 ? 69 LEU B C 1 ATOM 6156 O O . LEU B 1 33 ? 56.945 63.421 97.338 1.00 29.43 ? 69 LEU B O 1 ATOM 6157 C CB . LEU B 1 33 ? 54.036 64.461 97.853 1.00 32.97 ? 69 LEU B CB 1 ATOM 6158 C CG . LEU B 1 33 ? 52.892 65.287 98.428 1.00 32.34 ? 69 LEU B CG 1 ATOM 6159 C CD1 . LEU B 1 33 ? 52.010 65.799 97.298 1.00 36.37 ? 69 LEU B CD1 1 ATOM 6160 C CD2 . LEU B 1 33 ? 52.085 64.487 99.416 1.00 28.76 ? 69 LEU B CD2 1 ATOM 6161 N N . TYR B 1 34 ? 55.768 61.703 98.172 1.00 33.26 ? 70 TYR B N 1 ATOM 6162 C CA . TYR B 1 34 ? 56.520 60.696 97.443 1.00 34.41 ? 70 TYR B CA 1 ATOM 6163 C C . TYR B 1 34 ? 55.540 59.604 97.114 1.00 36.16 ? 70 TYR B C 1 ATOM 6164 O O . TYR B 1 34 ? 54.758 59.206 97.981 1.00 38.79 ? 70 TYR B O 1 ATOM 6165 C CB . TYR B 1 34 ? 57.665 60.150 98.303 1.00 33.69 ? 70 TYR B CB 1 ATOM 6166 C CG . TYR B 1 34 ? 58.438 59.026 97.635 1.00 36.68 ? 70 TYR B CG 1 ATOM 6167 C CD1 . TYR B 1 34 ? 59.198 59.256 96.490 1.00 36.76 ? 70 TYR B CD1 1 ATOM 6168 C CD2 . TYR B 1 34 ? 58.409 57.735 98.145 1.00 42.49 ? 70 TYR B CD2 1 ATOM 6169 C CE1 . TYR B 1 34 ? 59.900 58.230 95.875 1.00 37.49 ? 70 TYR B CE1 1 ATOM 6170 C CE2 . TYR B 1 34 ? 59.114 56.706 97.535 1.00 39.63 ? 70 TYR B CE2 1 ATOM 6171 C CZ . TYR B 1 34 ? 59.852 56.959 96.408 1.00 41.49 ? 70 TYR B CZ 1 ATOM 6172 O OH . TYR B 1 34 ? 60.547 55.935 95.807 1.00 45.60 ? 70 TYR B OH 1 ATOM 6173 N N . LYS B 1 35 ? 55.544 59.141 95.866 1.00 42.13 ? 71 LYS B N 1 ATOM 6174 C CA . LYS B 1 35 ? 54.623 58.089 95.447 1.00 42.90 ? 71 LYS B CA 1 ATOM 6175 C C . LYS B 1 35 ? 55.354 56.766 95.449 1.00 46.28 ? 71 LYS B C 1 ATOM 6176 O O . LYS B 1 35 ? 56.315 56.581 94.708 1.00 47.57 ? 71 LYS B O 1 ATOM 6177 C CB . LYS B 1 35 ? 54.043 58.361 94.058 1.00 44.25 ? 71 LYS B CB 1 ATOM 6178 C CG . LYS B 1 35 ? 52.902 57.409 93.689 1.00 47.85 ? 71 LYS B CG 1 ATOM 6179 C CD . LYS B 1 35 ? 52.207 57.774 92.361 1.00 52.35 ? 71 LYS B CD 1 ATOM 6180 C CE . LYS B 1 35 ? 53.053 57.399 91.135 1.00 56.38 ? 71 LYS B CE 1 ATOM 6181 N NZ . LYS B 1 35 ? 52.379 57.735 89.833 1.00 54.35 ? 71 LYS B NZ 1 ATOM 6182 N N . GLN B 1 36 ? 54.908 55.856 96.306 1.00 51.54 ? 72 GLN B N 1 ATOM 6183 C CA . GLN B 1 36 ? 55.530 54.547 96.435 1.00 50.94 ? 72 GLN B CA 1 ATOM 6184 C C . GLN B 1 36 ? 54.483 53.454 96.275 1.00 54.36 ? 72 GLN B C 1 ATOM 6185 O O . GLN B 1 36 ? 53.478 53.440 96.990 1.00 52.22 ? 72 GLN B O 1 ATOM 6186 C CB . GLN B 1 36 ? 56.198 54.416 97.793 1.00 50.80 ? 72 GLN B CB 1 ATOM 6187 C CG . GLN B 1 36 ? 57.313 53.399 97.822 1.00 59.14 ? 72 GLN B CG 1 ATOM 6188 C CD . GLN B 1 36 ? 57.785 53.135 99.231 1.00 64.39 ? 72 GLN B CD 1 ATOM 6189 O OE1 . GLN B 1 36 ? 56.976 52.862 100.116 1.00 61.76 ? 72 GLN B OE1 1 ATOM 6190 N NE2 . GLN B 1 36 ? 59.098 53.232 99.455 1.00 61.38 ? 72 GLN B NE2 1 ATOM 6191 N N . GLU B 1 37 ? 54.723 52.545 95.335 1.00 58.20 ? 73 GLU B N 1 ATOM 6192 C CA . GLU B 1 37 ? 53.769 51.482 95.032 1.00 58.61 ? 73 GLU B CA 1 ATOM 6193 C C . GLU B 1 37 ? 52.385 52.053 94.755 1.00 55.40 ? 73 GLU B C 1 ATOM 6194 O O . GLU B 1 37 ? 51.378 51.508 95.207 1.00 56.43 ? 73 GLU B O 1 ATOM 6195 C CB . GLU B 1 37 ? 53.710 50.470 96.181 1.00 57.12 ? 73 GLU B CB 1 ATOM 6196 C CG . GLU B 1 37 ? 54.824 49.429 96.141 1.00 62.75 ? 73 GLU B CG 1 ATOM 6197 C CD . GLU B 1 37 ? 54.933 48.631 97.433 1.00 73.91 ? 73 GLU B CD 1 ATOM 6198 O OE1 . GLU B 1 37 ? 54.346 49.062 98.455 1.00 73.10 ? 73 GLU B OE1 1 ATOM 6199 O OE2 . GLU B 1 37 ? 55.610 47.575 97.426 1.00 72.65 ? 73 GLU B OE2 1 ATOM 6200 N N . ASN B 1 38 ? 52.343 53.156 94.011 1.00 56.28 ? 74 ASN B N 1 ATOM 6201 C CA . ASN B 1 38 ? 51.085 53.840 93.708 1.00 51.65 ? 74 ASN B CA 1 ATOM 6202 C C . ASN B 1 38 ? 50.379 54.485 94.903 1.00 50.32 ? 74 ASN B C 1 ATOM 6203 O O . ASN B 1 38 ? 49.348 55.132 94.737 1.00 44.28 ? 74 ASN B O 1 ATOM 6204 C CB . ASN B 1 38 ? 50.121 52.909 92.982 1.00 55.28 ? 74 ASN B CB 1 ATOM 6205 C CG . ASN B 1 38 ? 50.137 53.122 91.497 1.00 62.71 ? 74 ASN B CG 1 ATOM 6206 O OD1 . ASN B 1 38 ? 51.133 52.827 90.832 1.00 62.44 ? 74 ASN B OD1 1 ATOM 6207 N ND2 . ASN B 1 38 ? 49.034 53.644 90.959 1.00 62.21 ? 74 ASN B ND2 1 ATOM 6208 N N . ASN B 1 39 ? 50.918 54.297 96.105 1.00 46.29 ? 75 ASN B N 1 ATOM 6209 C CA . ASN B 1 39 ? 50.421 55.030 97.254 1.00 44.50 ? 75 ASN B CA 1 ATOM 6210 C C . ASN B 1 39 ? 51.125 56.372 97.315 1.00 42.36 ? 75 ASN B C 1 ATOM 6211 O O . ASN B 1 39 ? 52.330 56.449 97.103 1.00 44.62 ? 75 ASN B O 1 ATOM 6212 C CB . ASN B 1 39 ? 50.691 54.263 98.545 1.00 43.40 ? 75 ASN B CB 1 ATOM 6213 C CG . ASN B 1 39 ? 50.100 52.880 98.530 1.00 47.86 ? 75 ASN B CG 1 ATOM 6214 O OD1 . ASN B 1 39 ? 48.912 52.698 98.780 1.00 46.51 ? 75 ASN B OD1 1 ATOM 6215 N ND2 . ASN B 1 39 ? 50.931 51.889 98.240 1.00 53.59 ? 75 ASN B ND2 1 ATOM 6216 N N . ILE B 1 40 ? 50.379 57.431 97.593 1.00 38.73 ? 76 ILE B N 1 ATOM 6217 C CA . ILE B 1 40 ? 50.987 58.734 97.793 1.00 39.52 ? 76 ILE B CA 1 ATOM 6218 C C . ILE B 1 40 ? 51.254 58.969 99.283 1.00 38.35 ? 76 ILE B C 1 ATOM 6219 O O . ILE B 1 40 ? 50.342 58.923 100.105 1.00 37.25 ? 76 ILE B O 1 ATOM 6220 C CB . ILE B 1 40 ? 50.112 59.850 97.229 1.00 43.10 ? 76 ILE B CB 1 ATOM 6221 C CG1 . ILE B 1 40 ? 50.009 59.710 95.708 1.00 41.79 ? 76 ILE B CG1 1 ATOM 6222 C CG2 . ILE B 1 40 ? 50.668 61.229 97.607 1.00 36.95 ? 76 ILE B CG2 1 ATOM 6223 C CD1 . ILE B 1 40 ? 48.837 60.451 95.134 1.00 44.16 ? 76 ILE B CD1 1 ATOM 6224 N N . LEU B 1 41 ? 52.513 59.220 99.611 1.00 37.48 ? 77 LEU B N 1 ATOM 6225 C CA . LEU B 1 41 ? 52.938 59.384 100.996 1.00 36.39 ? 77 LEU B CA 1 ATOM 6226 C C . LEU B 1 41 ? 53.378 60.815 101.288 1.00 37.15 ? 77 LEU B C 1 ATOM 6227 O O . LEU B 1 41 ? 53.788 61.549 100.380 1.00 31.24 ? 77 LEU B O 1 ATOM 6228 C CB . LEU B 1 41 ? 54.095 58.433 101.277 1.00 31.81 ? 77 LEU B CB 1 ATOM 6229 C CG . LEU B 1 41 ? 53.764 56.977 100.972 1.00 42.58 ? 77 LEU B CG 1 ATOM 6230 C CD1 . LEU B 1 41 ? 55.013 56.122 101.017 1.00 52.36 ? 77 LEU B CD1 1 ATOM 6231 C CD2 . LEU B 1 41 ? 52.742 56.485 101.962 1.00 40.90 ? 77 LEU B CD2 1 ATOM 6232 N N . VAL B 1 42 ? 53.264 61.210 102.555 1.00 33.92 ? 78 VAL B N 1 ATOM 6233 C CA . VAL B 1 42 ? 53.834 62.461 103.035 1.00 31.14 ? 78 VAL B CA 1 ATOM 6234 C C . VAL B 1 42 ? 55.000 62.084 103.938 1.00 32.17 ? 78 VAL B C 1 ATOM 6235 O O . VAL B 1 42 ? 54.841 61.273 104.842 1.00 33.50 ? 78 VAL B O 1 ATOM 6236 C CB . VAL B 1 42 ? 52.822 63.268 103.876 1.00 35.05 ? 78 VAL B CB 1 ATOM 6237 C CG1 . VAL B 1 42 ? 53.433 64.591 104.322 1.00 32.95 ? 78 VAL B CG1 1 ATOM 6238 C CG2 . VAL B 1 42 ? 51.543 63.496 103.107 1.00 37.79 ? 78 VAL B CG2 1 ATOM 6239 N N . PHE B 1 43 ? 56.172 62.645 103.681 1.00 30.72 ? 79 PHE B N 1 ATOM 6240 C CA . PHE B 1 43 ? 57.338 62.402 104.524 1.00 34.59 ? 79 PHE B CA 1 ATOM 6241 C C . PHE B 1 43 ? 57.696 63.642 105.335 1.00 33.12 ? 79 PHE B C 1 ATOM 6242 O O . PHE B 1 43 ? 57.583 64.773 104.848 1.00 28.51 ? 79 PHE B O 1 ATOM 6243 C CB . PHE B 1 43 ? 58.551 62.002 103.679 1.00 31.93 ? 79 PHE B CB 1 ATOM 6244 C CG . PHE B 1 43 ? 58.546 60.566 103.257 1.00 35.34 ? 79 PHE B CG 1 ATOM 6245 C CD1 . PHE B 1 43 ? 57.745 60.144 102.208 1.00 33.66 ? 79 PHE B CD1 1 ATOM 6246 C CD2 . PHE B 1 43 ? 59.343 59.635 103.908 1.00 34.30 ? 79 PHE B CD2 1 ATOM 6247 C CE1 . PHE B 1 43 ? 57.738 58.818 101.822 1.00 35.83 ? 79 PHE B CE1 1 ATOM 6248 C CE2 . PHE B 1 43 ? 59.344 58.306 103.520 1.00 35.81 ? 79 PHE B CE2 1 ATOM 6249 C CZ . PHE B 1 43 ? 58.537 57.897 102.481 1.00 35.12 ? 79 PHE B CZ 1 ATOM 6250 N N . ASN B 1 44 ? 58.134 63.409 106.567 1.00 30.40 ? 80 ASN B N 1 ATOM 6251 C CA . ASN B 1 44 ? 58.705 64.438 107.419 1.00 29.36 ? 80 ASN B CA 1 ATOM 6252 C C . ASN B 1 44 ? 60.201 64.406 107.201 1.00 29.41 ? 80 ASN B C 1 ATOM 6253 O O . ASN B 1 44 ? 60.832 63.370 107.429 1.00 28.35 ? 80 ASN B O 1 ATOM 6254 C CB . ASN B 1 44 ? 58.387 64.130 108.881 1.00 27.63 ? 80 ASN B CB 1 ATOM 6255 C CG . ASN B 1 44 ? 59.085 65.066 109.841 1.00 28.51 ? 80 ASN B CG 1 ATOM 6256 O OD1 . ASN B 1 44 ? 60.315 65.052 109.961 1.00 29.74 ? 80 ASN B OD1 1 ATOM 6257 N ND2 . ASN B 1 44 ? 58.305 65.870 110.550 1.00 26.73 ? 80 ASN B ND2 1 ATOM 6258 N N . ALA B 1 45 ? 60.779 65.519 106.745 1.00 29.22 ? 81 ALA B N 1 ATOM 6259 C CA . ALA B 1 45 ? 62.189 65.515 106.344 1.00 28.54 ? 81 ALA B CA 1 ATOM 6260 C C . ALA B 1 45 ? 63.136 65.316 107.520 1.00 29.19 ? 81 ALA B C 1 ATOM 6261 O O . ALA B 1 45 ? 64.156 64.640 107.404 1.00 28.95 ? 81 ALA B O 1 ATOM 6262 C CB . ALA B 1 45 ? 62.554 66.784 105.577 1.00 26.38 ? 81 ALA B CB 1 ATOM 6263 N N . GLU B 1 46 ? 62.816 65.936 108.647 1.00 29.39 ? 82 GLU B N 1 ATOM 6264 C CA . GLU B 1 46 ? 63.718 65.913 109.787 1.00 32.00 ? 82 GLU B CA 1 ATOM 6265 C C . GLU B 1 46 ? 63.902 64.493 110.341 1.00 30.50 ? 82 GLU B C 1 ATOM 6266 O O . GLU B 1 46 ? 65.013 64.061 110.633 1.00 33.33 ? 82 GLU B O 1 ATOM 6267 C CB . GLU B 1 46 ? 63.192 66.844 110.887 1.00 35.72 ? 82 GLU B CB 1 ATOM 6268 C CG . GLU B 1 46 ? 64.043 66.849 112.143 1.00 40.70 ? 82 GLU B CG 1 ATOM 6269 C CD . GLU B 1 46 ? 65.485 67.248 111.856 1.00 52.73 ? 82 GLU B CD 1 ATOM 6270 O OE1 . GLU B 1 46 ? 65.688 68.305 111.207 1.00 57.15 ? 82 GLU B OE1 1 ATOM 6271 O OE2 . GLU B 1 46 ? 66.414 66.500 112.263 1.00 56.42 ? 82 GLU B OE2 1 ATOM 6272 N N . TYR B 1 47 ? 62.802 63.770 110.486 1.00 30.51 ? 83 TYR B N 1 ATOM 6273 C CA . TYR B 1 47 ? 62.845 62.487 111.181 1.00 34.45 ? 83 TYR B CA 1 ATOM 6274 C C . TYR B 1 47 ? 62.635 61.281 110.263 1.00 34.77 ? 83 TYR B C 1 ATOM 6275 O O . TYR B 1 47 ? 63.013 60.167 110.608 1.00 34.30 ? 83 TYR B O 1 ATOM 6276 C CB . TYR B 1 47 ? 61.837 62.480 112.325 1.00 34.14 ? 83 TYR B CB 1 ATOM 6277 C CG . TYR B 1 47 ? 62.130 63.551 113.355 1.00 31.21 ? 83 TYR B CG 1 ATOM 6278 C CD1 . TYR B 1 47 ? 63.160 63.391 114.263 1.00 31.52 ? 83 TYR B CD1 1 ATOM 6279 C CD2 . TYR B 1 47 ? 61.385 64.720 113.401 1.00 29.62 ? 83 TYR B CD2 1 ATOM 6280 C CE1 . TYR B 1 47 ? 63.440 64.370 115.212 1.00 36.95 ? 83 TYR B CE1 1 ATOM 6281 C CE2 . TYR B 1 47 ? 61.650 65.697 114.339 1.00 33.11 ? 83 TYR B CE2 1 ATOM 6282 C CZ . TYR B 1 47 ? 62.682 65.519 115.238 1.00 35.87 ? 83 TYR B CZ 1 ATOM 6283 O OH . TYR B 1 47 ? 62.953 66.492 116.170 1.00 39.99 ? 83 TYR B OH 1 ATOM 6284 N N . GLY B 1 48 ? 62.022 61.510 109.106 1.00 31.82 ? 84 GLY B N 1 ATOM 6285 C CA . GLY B 1 48 ? 61.924 60.477 108.091 1.00 30.80 ? 84 GLY B CA 1 ATOM 6286 C C . GLY B 1 48 ? 60.656 59.668 108.208 1.00 30.37 ? 84 GLY B C 1 ATOM 6287 O O . GLY B 1 48 ? 60.420 58.766 107.405 1.00 27.60 ? 84 GLY B O 1 ATOM 6288 N N . ASN B 1 49 ? 59.837 59.966 109.214 1.00 28.62 ? 85 ASN B N 1 ATOM 6289 C CA . ASN B 1 49 ? 58.602 59.221 109.357 1.00 30.82 ? 85 ASN B CA 1 ATOM 6290 C C . ASN B 1 49 ? 57.628 59.637 108.269 1.00 36.30 ? 85 ASN B C 1 ATOM 6291 O O . ASN B 1 49 ? 57.748 60.731 107.716 1.00 30.59 ? 85 ASN B O 1 ATOM 6292 C CB . ASN B 1 49 ? 57.992 59.363 110.753 1.00 33.06 ? 85 ASN B CB 1 ATOM 6293 C CG . ASN B 1 49 ? 57.590 60.780 111.083 1.00 31.39 ? 85 ASN B CG 1 ATOM 6294 O OD1 . ASN B 1 49 ? 58.435 61.664 111.172 1.00 30.49 ? 85 ASN B OD1 1 ATOM 6295 N ND2 . ASN B 1 49 ? 56.290 60.994 111.291 1.00 31.50 ? 85 ASN B ND2 1 ATOM 6296 N N . SER B 1 50 ? 56.677 58.759 107.962 1.00 35.04 ? 86 SER B N 1 ATOM 6297 C CA . SER B 1 50 ? 55.741 58.997 106.873 1.00 34.09 ? 86 SER B CA 1 ATOM 6298 C C . SER B 1 50 ? 54.335 58.532 107.218 1.00 36.80 ? 86 SER B C 1 ATOM 6299 O O . SER B 1 50 ? 54.135 57.728 108.132 1.00 35.16 ? 86 SER B O 1 ATOM 6300 C CB . SER B 1 50 ? 56.210 58.287 105.607 1.00 36.18 ? 86 SER B CB 1 ATOM 6301 O OG . SER B 1 50 ? 56.506 56.923 105.857 1.00 36.96 ? 86 SER B OG 1 ATOM 6302 N N . SER B 1 51 ? 53.374 59.051 106.467 1.00 32.02 ? 87 SER B N 1 ATOM 6303 C CA . SER B 1 51 ? 51.980 58.660 106.562 1.00 32.15 ? 87 SER B CA 1 ATOM 6304 C C . SER B 1 51 ? 51.415 58.466 105.158 1.00 39.33 ? 87 SER B C 1 ATOM 6305 O O . SER B 1 51 ? 51.738 59.218 104.241 1.00 36.02 ? 87 SER B O 1 ATOM 6306 C CB . SER B 1 51 ? 51.182 59.739 107.287 1.00 36.11 ? 87 SER B CB 1 ATOM 6307 O OG . SER B 1 51 ? 51.543 59.800 108.658 1.00 42.71 ? 87 SER B OG 1 ATOM 6308 N N . VAL B 1 52 ? 50.578 57.451 104.986 1.00 38.72 ? 88 VAL B N 1 ATOM 6309 C CA . VAL B 1 52 ? 49.906 57.240 103.716 1.00 38.67 ? 88 VAL B CA 1 ATOM 6310 C C . VAL B 1 52 ? 48.837 58.318 103.537 1.00 39.73 ? 88 VAL B C 1 ATOM 6311 O O . VAL B 1 52 ? 47.925 58.447 104.351 1.00 37.50 ? 88 VAL B O 1 ATOM 6312 C CB . VAL B 1 52 ? 49.292 55.819 103.636 1.00 38.92 ? 88 VAL B CB 1 ATOM 6313 C CG1 . VAL B 1 52 ? 48.448 55.540 104.864 1.00 43.52 ? 88 VAL B CG1 1 ATOM 6314 C CG2 . VAL B 1 52 ? 48.454 55.668 102.376 1.00 41.34 ? 88 VAL B CG2 1 ATOM 6315 N N . PHE B 1 53 ? 48.964 59.115 102.484 1.00 40.15 ? 89 PHE B N 1 ATOM 6316 C CA . PHE B 1 53 ? 48.034 60.217 102.252 1.00 38.70 ? 89 PHE B CA 1 ATOM 6317 C C . PHE B 1 53 ? 46.886 59.786 101.337 1.00 42.86 ? 89 PHE B C 1 ATOM 6318 O O . PHE B 1 53 ? 45.749 60.234 101.490 1.00 41.16 ? 89 PHE B O 1 ATOM 6319 C CB . PHE B 1 53 ? 48.777 61.409 101.649 1.00 42.96 ? 89 PHE B CB 1 ATOM 6320 C CG . PHE B 1 53 ? 47.910 62.606 101.408 1.00 45.47 ? 89 PHE B CG 1 ATOM 6321 C CD1 . PHE B 1 53 ? 47.309 63.267 102.468 1.00 47.98 ? 89 PHE B CD1 1 ATOM 6322 C CD2 . PHE B 1 53 ? 47.704 63.081 100.120 1.00 46.03 ? 89 PHE B CD2 1 ATOM 6323 C CE1 . PHE B 1 53 ? 46.514 64.373 102.249 1.00 51.80 ? 89 PHE B CE1 1 ATOM 6324 C CE2 . PHE B 1 53 ? 46.909 64.189 99.897 1.00 46.13 ? 89 PHE B CE2 1 ATOM 6325 C CZ . PHE B 1 53 ? 46.315 64.835 100.963 1.00 41.92 ? 89 PHE B CZ 1 ATOM 6326 N N . LEU B 1 54 ? 47.192 58.913 100.384 1.00 35.74 ? 90 LEU B N 1 ATOM 6327 C CA . LEU B 1 54 ? 46.180 58.368 99.494 1.00 41.55 ? 90 LEU B CA 1 ATOM 6328 C C . LEU B 1 54 ? 46.637 56.974 99.084 1.00 40.02 ? 90 LEU B C 1 ATOM 6329 O O . LEU B 1 54 ? 47.711 56.814 98.502 1.00 37.03 ? 90 LEU B O 1 ATOM 6330 C CB . LEU B 1 54 ? 46.002 59.277 98.264 1.00 47.81 ? 90 LEU B CB 1 ATOM 6331 C CG . LEU B 1 54 ? 44.786 59.069 97.353 1.00 48.14 ? 90 LEU B CG 1 ATOM 6332 N N . GLU B 1 55 ? 45.829 55.970 99.415 1.00 44.23 ? 91 GLU B N 1 ATOM 6333 C CA . GLU B 1 55 ? 46.134 54.579 99.083 1.00 47.03 ? 91 GLU B CA 1 ATOM 6334 C C . GLU B 1 55 ? 45.922 54.262 97.605 1.00 49.19 ? 91 GLU B C 1 ATOM 6335 O O . GLU B 1 55 ? 45.025 54.808 96.966 1.00 50.19 ? 91 GLU B O 1 ATOM 6336 C CB . GLU B 1 55 ? 45.302 53.631 99.954 1.00 53.27 ? 91 GLU B CB 1 ATOM 6337 C CG . GLU B 1 55 ? 45.661 53.710 101.437 1.00 51.60 ? 91 GLU B CG 1 ATOM 6338 C CD . GLU B 1 55 ? 44.800 52.816 102.313 1.00 64.84 ? 91 GLU B CD 1 ATOM 6339 O OE1 . GLU B 1 55 ? 43.871 52.168 101.775 1.00 63.20 ? 91 GLU B OE1 1 ATOM 6340 O OE2 . GLU B 1 55 ? 45.052 52.767 103.544 1.00 65.39 ? 91 GLU B OE2 1 ATOM 6341 N N . ASN B 1 56 ? 46.754 53.368 97.074 1.00 50.87 ? 92 ASN B N 1 ATOM 6342 C CA . ASN B 1 56 ? 46.681 52.968 95.671 1.00 51.31 ? 92 ASN B CA 1 ATOM 6343 C C . ASN B 1 56 ? 45.362 52.320 95.296 1.00 55.60 ? 92 ASN B C 1 ATOM 6344 O O . ASN B 1 56 ? 45.133 52.006 94.132 1.00 59.18 ? 92 ASN B O 1 ATOM 6345 C CB . ASN B 1 56 ? 47.850 52.040 95.287 1.00 52.05 ? 92 ASN B CB 1 ATOM 6346 C CG . ASN B 1 56 ? 47.922 50.768 96.145 1.00 56.21 ? 92 ASN B CG 1 ATOM 6347 O OD1 . ASN B 1 56 ? 46.990 50.441 96.885 1.00 51.76 ? 92 ASN B OD1 1 ATOM 6348 N ND2 . ASN B 1 56 ? 49.048 50.048 96.036 1.00 57.87 ? 92 ASN B ND2 1 ATOM 6349 N N . SER B 1 57 ? 44.499 52.120 96.286 1.00 54.20 ? 93 SER B N 1 ATOM 6350 C CA . SER B 1 57 ? 43.204 51.503 96.050 1.00 58.62 ? 93 SER B CA 1 ATOM 6351 C C . SER B 1 57 ? 42.118 52.551 95.811 1.00 57.88 ? 93 SER B C 1 ATOM 6352 O O . SER B 1 57 ? 41.100 52.270 95.184 1.00 59.52 ? 93 SER B O 1 ATOM 6353 C CB . SER B 1 57 ? 42.812 50.626 97.243 1.00 54.59 ? 93 SER B CB 1 ATOM 6354 O OG . SER B 1 57 ? 42.581 51.413 98.405 1.00 51.12 ? 93 SER B OG 1 ATOM 6355 N N . THR B 1 58 ? 42.343 53.759 96.313 1.00 57.28 ? 94 THR B N 1 ATOM 6356 C CA . THR B 1 58 ? 41.287 54.768 96.391 1.00 58.30 ? 94 THR B CA 1 ATOM 6357 C C . THR B 1 58 ? 40.409 54.857 95.150 1.00 62.00 ? 94 THR B C 1 ATOM 6358 O O . THR B 1 58 ? 39.182 54.767 95.244 1.00 64.14 ? 94 THR B O 1 ATOM 6359 C CB . THR B 1 58 ? 41.850 56.158 96.698 1.00 55.12 ? 94 THR B CB 1 ATOM 6360 O OG1 . THR B 1 58 ? 42.485 56.129 97.978 1.00 56.47 ? 94 THR B OG1 1 ATOM 6361 C CG2 . THR B 1 58 ? 40.731 57.188 96.726 1.00 57.50 ? 94 THR B CG2 1 ATOM 6362 N N . PHE B 1 59 ? 41.032 55.026 93.989 1.00 58.06 ? 95 PHE B N 1 ATOM 6363 C CA . PHE B 1 59 ? 40.265 55.262 92.774 1.00 58.14 ? 95 PHE B CA 1 ATOM 6364 C C . PHE B 1 59 ? 40.090 53.994 91.929 1.00 62.95 ? 95 PHE B C 1 ATOM 6365 O O . PHE B 1 59 ? 39.857 54.068 90.722 1.00 58.86 ? 95 PHE B O 1 ATOM 6366 C CB . PHE B 1 59 ? 40.894 56.409 91.970 1.00 58.87 ? 95 PHE B CB 1 ATOM 6367 C CG . PHE B 1 59 ? 41.096 57.666 92.776 1.00 53.12 ? 95 PHE B CG 1 ATOM 6368 C CD1 . PHE B 1 59 ? 40.009 58.438 93.163 1.00 53.22 ? 95 PHE B CD1 1 ATOM 6369 C CD2 . PHE B 1 59 ? 42.367 58.064 93.165 1.00 51.27 ? 95 PHE B CD2 1 ATOM 6370 C CE1 . PHE B 1 59 ? 40.185 59.593 93.916 1.00 47.14 ? 95 PHE B CE1 1 ATOM 6371 C CE2 . PHE B 1 59 ? 42.548 59.216 93.917 1.00 47.81 ? 95 PHE B CE2 1 ATOM 6372 C CZ . PHE B 1 59 ? 41.451 59.980 94.293 1.00 45.33 ? 95 PHE B CZ 1 ATOM 6373 N N . ASP B 1 60 ? 40.182 52.833 92.576 1.00 61.94 ? 96 ASP B N 1 ATOM 6374 C CA . ASP B 1 60 ? 40.065 51.556 91.877 1.00 64.54 ? 96 ASP B CA 1 ATOM 6375 C C . ASP B 1 60 ? 38.812 51.494 91.007 1.00 64.64 ? 96 ASP B C 1 ATOM 6376 O O . ASP B 1 60 ? 38.813 50.856 89.954 1.00 64.46 ? 96 ASP B O 1 ATOM 6377 C CB . ASP B 1 60 ? 40.086 50.378 92.861 1.00 65.02 ? 96 ASP B CB 1 ATOM 6378 C CG . ASP B 1 60 ? 41.497 50.038 93.349 1.00 71.40 ? 96 ASP B CG 1 ATOM 6379 O OD1 . ASP B 1 60 ? 42.480 50.409 92.663 1.00 71.72 ? 96 ASP B OD1 1 ATOM 6380 O OD2 . ASP B 1 60 ? 41.623 49.390 94.415 1.00 70.89 ? 96 ASP B OD2 1 ATOM 6381 N N . GLU B 1 61 ? 37.748 52.161 91.443 1.00 61.73 ? 97 GLU B N 1 ATOM 6382 C CA . GLU B 1 61 ? 36.504 52.174 90.675 1.00 66.23 ? 97 GLU B CA 1 ATOM 6383 C C . GLU B 1 61 ? 36.289 53.516 89.973 1.00 64.95 ? 97 GLU B C 1 ATOM 6384 O O . GLU B 1 61 ? 35.170 53.841 89.570 1.00 64.31 ? 97 GLU B O 1 ATOM 6385 C CB . GLU B 1 61 ? 35.301 51.828 91.565 1.00 63.90 ? 97 GLU B CB 1 ATOM 6386 C CG . GLU B 1 61 ? 35.312 50.396 92.101 1.00 66.02 ? 97 GLU B CG 1 ATOM 6387 N N . PHE B 1 62 ? 37.364 54.287 89.826 1.00 61.33 ? 98 PHE B N 1 ATOM 6388 C CA . PHE B 1 62 ? 37.292 55.587 89.165 1.00 57.98 ? 98 PHE B CA 1 ATOM 6389 C C . PHE B 1 62 ? 36.691 55.487 87.758 1.00 58.18 ? 98 PHE B C 1 ATOM 6390 O O . PHE B 1 62 ? 35.891 56.336 87.351 1.00 59.31 ? 98 PHE B O 1 ATOM 6391 C CB . PHE B 1 62 ? 38.672 56.239 89.119 1.00 58.07 ? 98 PHE B CB 1 ATOM 6392 C CG . PHE B 1 62 ? 38.672 57.612 88.517 1.00 56.35 ? 98 PHE B CG 1 ATOM 6393 C CD1 . PHE B 1 62 ? 37.918 58.628 89.080 1.00 55.00 ? 98 PHE B CD1 1 ATOM 6394 C CD2 . PHE B 1 62 ? 39.435 57.892 87.393 1.00 55.06 ? 98 PHE B CD2 1 ATOM 6395 C CE1 . PHE B 1 62 ? 37.917 59.900 88.528 1.00 52.85 ? 98 PHE B CE1 1 ATOM 6396 C CE2 . PHE B 1 62 ? 39.441 59.159 86.836 1.00 52.54 ? 98 PHE B CE2 1 ATOM 6397 C CZ . PHE B 1 62 ? 38.680 60.166 87.407 1.00 53.85 ? 98 PHE B CZ 1 ATOM 6398 N N . GLY B 1 63 ? 37.068 54.449 87.020 1.00 54.07 ? 99 GLY B N 1 ATOM 6399 C CA . GLY B 1 63 ? 36.481 54.214 85.709 1.00 54.99 ? 99 GLY B CA 1 ATOM 6400 C C . GLY B 1 63 ? 37.353 54.670 84.548 1.00 54.88 ? 99 GLY B C 1 ATOM 6401 O O . GLY B 1 63 ? 37.055 54.400 83.380 1.00 55.95 ? 99 GLY B O 1 ATOM 6402 N N . HIS B 1 64 ? 38.431 55.375 84.869 1.00 52.64 ? 100 HIS B N 1 ATOM 6403 C CA . HIS B 1 64 ? 39.398 55.799 83.868 1.00 54.46 ? 100 HIS B CA 1 ATOM 6404 C C . HIS B 1 64 ? 40.797 55.540 84.387 1.00 51.10 ? 100 HIS B C 1 ATOM 6405 O O . HIS B 1 64 ? 41.049 55.655 85.583 1.00 49.41 ? 100 HIS B O 1 ATOM 6406 C CB . HIS B 1 64 ? 39.248 57.290 83.581 1.00 50.19 ? 100 HIS B CB 1 ATOM 6407 C CG . HIS B 1 64 ? 37.908 57.669 83.039 1.00 50.10 ? 100 HIS B CG 1 ATOM 6408 N ND1 . HIS B 1 64 ? 36.928 58.246 83.817 1.00 50.11 ? 100 HIS B ND1 1 ATOM 6409 C CD2 . HIS B 1 64 ? 37.385 57.552 81.796 1.00 51.23 ? 100 HIS B CD2 1 ATOM 6410 C CE1 . HIS B 1 64 ? 35.858 58.472 83.076 1.00 49.30 ? 100 HIS B CE1 1 ATOM 6411 N NE2 . HIS B 1 64 ? 36.109 58.061 81.846 1.00 50.20 ? 100 HIS B NE2 1 ATOM 6412 N N . SER B 1 65 ? 41.708 55.188 83.491 1.00 47.89 ? 101 SER B N 1 ATOM 6413 C CA . SER B 1 65 ? 43.109 55.133 83.856 1.00 46.97 ? 101 SER B CA 1 ATOM 6414 C C . SER B 1 65 ? 43.540 56.561 84.203 1.00 46.41 ? 101 SER B C 1 ATOM 6415 O O . SER B 1 65 ? 43.384 57.468 83.392 1.00 46.40 ? 101 SER B O 1 ATOM 6416 C CB . SER B 1 65 ? 43.919 54.579 82.682 1.00 53.25 ? 101 SER B CB 1 ATOM 6417 O OG . SER B 1 65 ? 45.306 54.544 82.977 1.00 56.14 ? 101 SER B OG 1 ATOM 6418 N N . ILE B 1 66 ? 44.041 56.774 85.416 1.00 46.62 ? 102 ILE B N 1 ATOM 6419 C CA . ILE B 1 66 ? 44.498 58.102 85.835 1.00 42.83 ? 102 ILE B CA 1 ATOM 6420 C C . ILE B 1 66 ? 45.938 58.364 85.397 1.00 42.06 ? 102 ILE B C 1 ATOM 6421 O O . ILE B 1 66 ? 46.866 57.700 85.851 1.00 39.24 ? 102 ILE B O 1 ATOM 6422 C CB . ILE B 1 66 ? 44.369 58.289 87.363 1.00 41.98 ? 102 ILE B CB 1 ATOM 6423 C CG1 . ILE B 1 66 ? 42.910 58.536 87.738 1.00 44.56 ? 102 ILE B CG1 1 ATOM 6424 C CG2 . ILE B 1 66 ? 45.231 59.453 87.856 1.00 38.92 ? 102 ILE B CG2 1 ATOM 6425 C CD1 . ILE B 1 66 ? 42.618 58.360 89.209 1.00 44.44 ? 102 ILE B CD1 1 ATOM 6426 N N . ASN B 1 67 ? 46.122 59.344 84.521 1.00 36.80 ? 103 ASN B N 1 ATOM 6427 C CA . ASN B 1 67 ? 47.444 59.619 83.959 1.00 38.38 ? 103 ASN B CA 1 ATOM 6428 C C . ASN B 1 67 ? 48.388 60.328 84.925 1.00 40.47 ? 103 ASN B C 1 ATOM 6429 O O . ASN B 1 67 ? 49.593 60.079 84.915 1.00 37.66 ? 103 ASN B O 1 ATOM 6430 C CB . ASN B 1 67 ? 47.320 60.428 82.663 1.00 38.52 ? 103 ASN B CB 1 ATOM 6431 C CG . ASN B 1 67 ? 48.666 60.719 82.028 1.00 39.46 ? 103 ASN B CG 1 ATOM 6432 O OD1 . ASN B 1 67 ? 49.143 61.860 82.033 1.00 39.59 ? 103 ASN B OD1 1 ATOM 6433 N ND2 . ASN B 1 67 ? 49.286 59.686 81.477 1.00 36.84 ? 103 ASN B ND2 1 ATOM 6434 N N . ASP B 1 68 ? 47.842 61.223 85.742 1.00 34.48 ? 104 ASP B N 1 ATOM 6435 C CA . ASP B 1 68 ? 48.643 61.984 86.691 1.00 37.01 ? 104 ASP B CA 1 ATOM 6436 C C . ASP B 1 68 ? 47.726 62.640 87.718 1.00 37.70 ? 104 ASP B C 1 ATOM 6437 O O . ASP B 1 68 ? 46.509 62.588 87.589 1.00 37.11 ? 104 ASP B O 1 ATOM 6438 C CB . ASP B 1 68 ? 49.491 63.039 85.970 1.00 39.77 ? 104 ASP B CB 1 ATOM 6439 C CG . ASP B 1 68 ? 50.782 63.381 86.727 1.00 48.71 ? 104 ASP B CG 1 ATOM 6440 O OD1 . ASP B 1 68 ? 50.902 63.031 87.930 1.00 47.63 ? 104 ASP B OD1 1 ATOM 6441 O OD2 . ASP B 1 68 ? 51.681 64.006 86.115 1.00 51.26 ? 104 ASP B OD2 1 ATOM 6442 N N . TYR B 1 69 ? 48.310 63.249 88.742 1.00 39.17 ? 105 TYR B N 1 ATOM 6443 C CA . TYR B 1 69 ? 47.532 63.886 89.794 1.00 34.63 ? 105 TYR B CA 1 ATOM 6444 C C . TYR B 1 69 ? 48.223 65.171 90.222 1.00 37.10 ? 105 TYR B C 1 ATOM 6445 O O . TYR B 1 69 ? 49.429 65.333 90.044 1.00 38.06 ? 105 TYR B O 1 ATOM 6446 C CB . TYR B 1 69 ? 47.414 62.952 91.009 1.00 38.14 ? 105 TYR B CB 1 ATOM 6447 C CG . TYR B 1 69 ? 48.717 62.799 91.760 1.00 37.94 ? 105 TYR B CG 1 ATOM 6448 C CD1 . TYR B 1 69 ? 49.080 63.708 92.749 1.00 41.75 ? 105 TYR B CD1 1 ATOM 6449 C CD2 . TYR B 1 69 ? 49.598 61.758 91.469 1.00 43.67 ? 105 TYR B CD2 1 ATOM 6450 C CE1 . TYR B 1 69 ? 50.284 63.586 93.427 1.00 42.92 ? 105 TYR B CE1 1 ATOM 6451 C CE2 . TYR B 1 69 ? 50.806 61.623 92.147 1.00 40.08 ? 105 TYR B CE2 1 ATOM 6452 C CZ . TYR B 1 69 ? 51.140 62.542 93.123 1.00 46.03 ? 105 TYR B CZ 1 ATOM 6453 O OH . TYR B 1 69 ? 52.334 62.425 93.806 1.00 55.19 ? 105 TYR B OH 1 ATOM 6454 N N . SER B 1 70 ? 47.459 66.083 90.802 1.00 34.66 ? 106 SER B N 1 ATOM 6455 C CA . SER B 1 70 ? 48.033 67.280 91.382 1.00 31.32 ? 106 SER B CA 1 ATOM 6456 C C . SER B 1 70 ? 47.210 67.681 92.603 1.00 32.92 ? 106 SER B C 1 ATOM 6457 O O . SER B 1 70 ? 46.025 68.001 92.504 1.00 31.36 ? 106 SER B O 1 ATOM 6458 C CB . SER B 1 70 ? 48.098 68.415 90.355 1.00 33.37 ? 106 SER B CB 1 ATOM 6459 O OG . SER B 1 70 ? 48.558 69.611 90.962 1.00 35.12 ? 106 SER B OG 1 ATOM 6460 N N . ILE B 1 71 ? 47.856 67.645 93.760 1.00 33.02 ? 107 ILE B N 1 ATOM 6461 C CA . ILE B 1 71 ? 47.209 67.988 95.009 1.00 34.72 ? 107 ILE B CA 1 ATOM 6462 C C . ILE B 1 71 ? 47.290 69.498 95.179 1.00 34.76 ? 107 ILE B C 1 ATOM 6463 O O . ILE B 1 71 ? 48.311 70.114 94.872 1.00 33.43 ? 107 ILE B O 1 ATOM 6464 C CB . ILE B 1 71 ? 47.855 67.209 96.191 1.00 38.72 ? 107 ILE B CB 1 ATOM 6465 C CG1 . ILE B 1 71 ? 47.473 65.727 96.088 1.00 39.09 ? 107 ILE B CG1 1 ATOM 6466 C CG2 . ILE B 1 71 ? 47.397 67.746 97.520 1.00 36.61 ? 107 ILE B CG2 1 ATOM 6467 C CD1 . ILE B 1 71 ? 48.531 64.770 96.599 1.00 38.78 ? 107 ILE B CD1 1 ATOM 6468 N N . SER B 1 72 ? 46.197 70.105 95.618 1.00 33.96 ? 108 SER B N 1 ATOM 6469 C CA . SER B 1 72 ? 46.185 71.541 95.806 1.00 36.32 ? 108 SER B CA 1 ATOM 6470 C C . SER B 1 72 ? 47.153 71.877 96.934 1.00 40.56 ? 108 SER B C 1 ATOM 6471 O O . SER B 1 72 ? 47.460 71.018 97.757 1.00 42.14 ? 108 SER B O 1 ATOM 6472 C CB . SER B 1 72 ? 44.774 72.025 96.124 1.00 35.60 ? 108 SER B CB 1 ATOM 6473 O OG . SER B 1 72 ? 44.201 71.255 97.162 1.00 38.06 ? 108 SER B OG 1 ATOM 6474 N N . PRO B 1 73 ? 47.661 73.118 96.956 1.00 37.67 ? 109 PRO B N 1 ATOM 6475 C CA . PRO B 1 73 ? 48.703 73.514 97.905 1.00 36.80 ? 109 PRO B CA 1 ATOM 6476 C C . PRO B 1 73 ? 48.289 73.295 99.362 1.00 43.87 ? 109 PRO B C 1 ATOM 6477 O O . PRO B 1 73 ? 49.136 72.960 100.200 1.00 42.02 ? 109 PRO B O 1 ATOM 6478 C CB . PRO B 1 73 ? 48.874 75.011 97.629 1.00 39.56 ? 109 PRO B CB 1 ATOM 6479 C CG . PRO B 1 73 ? 48.428 75.184 96.219 1.00 38.31 ? 109 PRO B CG 1 ATOM 6480 C CD . PRO B 1 73 ? 47.324 74.200 96.013 1.00 35.75 ? 109 PRO B CD 1 ATOM 6481 N N . ASP B 1 74 ? 47.005 73.487 99.655 1.00 43.01 ? 110 ASP B N 1 ATOM 6482 C CA . ASP B 1 74 ? 46.495 73.338 101.015 1.00 41.05 ? 110 ASP B CA 1 ATOM 6483 C C . ASP B 1 74 ? 46.001 71.922 101.315 1.00 44.09 ? 110 ASP B C 1 ATOM 6484 O O . ASP B 1 74 ? 45.364 71.698 102.343 1.00 46.02 ? 110 ASP B O 1 ATOM 6485 C CB . ASP B 1 74 ? 45.370 74.344 101.281 1.00 40.23 ? 110 ASP B CB 1 ATOM 6486 C CG . ASP B 1 74 ? 44.148 74.108 100.400 1.00 43.96 ? 110 ASP B CG 1 ATOM 6487 O OD1 . ASP B 1 74 ? 44.066 73.050 99.735 1.00 38.08 ? 110 ASP B OD1 1 ATOM 6488 O OD2 . ASP B 1 74 ? 43.255 74.982 100.384 1.00 44.78 ? 110 ASP B OD2 1 ATOM 6489 N N . GLY B 1 75 ? 46.279 70.978 100.418 1.00 40.48 ? 111 GLY B N 1 ATOM 6490 C CA . GLY B 1 75 ? 45.903 69.588 100.620 1.00 39.49 ? 111 GLY B CA 1 ATOM 6491 C C . GLY B 1 75 ? 44.413 69.272 100.659 1.00 41.43 ? 111 GLY B C 1 ATOM 6492 O O . GLY B 1 75 ? 44.035 68.129 100.938 1.00 42.11 ? 111 GLY B O 1 ATOM 6493 N N . GLN B 1 76 ? 43.562 70.260 100.382 1.00 38.50 ? 112 GLN B N 1 ATOM 6494 C CA . GLN B 1 76 ? 42.106 70.065 100.440 1.00 35.56 ? 112 GLN B CA 1 ATOM 6495 C C . GLN B 1 76 ? 41.500 69.348 99.222 1.00 41.18 ? 112 GLN B C 1 ATOM 6496 O O . GLN B 1 76 ? 40.417 68.758 99.324 1.00 38.26 ? 112 GLN B O 1 ATOM 6497 C CB . GLN B 1 76 ? 41.386 71.400 100.656 1.00 36.43 ? 112 GLN B CB 1 ATOM 6498 C CG . GLN B 1 76 ? 41.796 72.119 101.941 1.00 45.45 ? 112 GLN B CG 1 ATOM 6499 C CD . GLN B 1 76 ? 40.820 73.211 102.360 1.00 49.12 ? 112 GLN B CD 1 ATOM 6500 O OE1 . GLN B 1 76 ? 39.672 73.255 101.904 1.00 50.51 ? 112 GLN B OE1 1 ATOM 6501 N NE2 . GLN B 1 76 ? 41.279 74.105 103.231 1.00 47.12 ? 112 GLN B NE2 1 ATOM 6502 N N . PHE B 1 77 ? 42.186 69.414 98.076 1.00 38.10 ? 113 PHE B N 1 ATOM 6503 C CA . PHE B 1 77 ? 41.697 68.796 96.834 1.00 36.33 ? 113 PHE B CA 1 ATOM 6504 C C . PHE B 1 77 ? 42.801 68.125 96.024 1.00 33.94 ? 113 PHE B C 1 ATOM 6505 O O . PHE B 1 77 ? 43.972 68.495 96.115 1.00 35.29 ? 113 PHE B O 1 ATOM 6506 C CB . PHE B 1 77 ? 41.011 69.836 95.943 1.00 35.91 ? 113 PHE B CB 1 ATOM 6507 C CG . PHE B 1 77 ? 39.875 70.538 96.603 1.00 37.84 ? 113 PHE B CG 1 ATOM 6508 C CD1 . PHE B 1 77 ? 38.588 70.046 96.496 1.00 38.51 ? 113 PHE B CD1 1 ATOM 6509 C CD2 . PHE B 1 77 ? 40.096 71.689 97.340 1.00 38.66 ? 113 PHE B CD2 1 ATOM 6510 C CE1 . PHE B 1 77 ? 37.532 70.694 97.106 1.00 43.43 ? 113 PHE B CE1 1 ATOM 6511 C CE2 . PHE B 1 77 ? 39.043 72.346 97.960 1.00 41.90 ? 113 PHE B CE2 1 ATOM 6512 C CZ . PHE B 1 77 ? 37.760 71.851 97.841 1.00 40.80 ? 113 PHE B CZ 1 ATOM 6513 N N . ILE B 1 78 ? 42.417 67.140 95.221 1.00 35.04 ? 114 ILE B N 1 ATOM 6514 C CA . ILE B 1 78 ? 43.335 66.555 94.260 1.00 36.60 ? 114 ILE B CA 1 ATOM 6515 C C . ILE B 1 78 ? 42.725 66.562 92.859 1.00 36.71 ? 114 ILE B C 1 ATOM 6516 O O . ILE B 1 78 ? 41.571 66.159 92.674 1.00 35.04 ? 114 ILE B O 1 ATOM 6517 C CB . ILE B 1 78 ? 43.761 65.132 94.672 1.00 35.35 ? 114 ILE B CB 1 ATOM 6518 C CG1 . ILE B 1 78 ? 44.738 64.546 93.654 1.00 39.21 ? 114 ILE B CG1 1 ATOM 6519 C CG2 . ILE B 1 78 ? 42.561 64.233 94.832 1.00 39.65 ? 114 ILE B CG2 1 ATOM 6520 C CD1 . ILE B 1 78 ? 45.357 63.221 94.102 1.00 38.98 ? 114 ILE B CD1 1 ATOM 6521 N N . LEU B 1 79 ? 43.494 67.056 91.887 1.00 36.38 ? 115 LEU B N 1 ATOM 6522 C CA . LEU B 1 79 ? 43.129 66.995 90.466 1.00 31.81 ? 115 LEU B CA 1 ATOM 6523 C C . LEU B 1 79 ? 43.484 65.626 89.903 1.00 32.59 ? 115 LEU B C 1 ATOM 6524 O O . LEU B 1 79 ? 44.606 65.175 90.067 1.00 34.31 ? 115 LEU B O 1 ATOM 6525 C CB . LEU B 1 79 ? 43.949 68.015 89.677 1.00 36.27 ? 115 LEU B CB 1 ATOM 6526 C CG . LEU B 1 79 ? 43.424 69.351 89.154 1.00 37.90 ? 115 LEU B CG 1 ATOM 6527 C CD1 . LEU B 1 79 ? 44.497 69.919 88.252 1.00 31.53 ? 115 LEU B CD1 1 ATOM 6528 C CD2 . LEU B 1 79 ? 42.114 69.209 88.393 1.00 33.96 ? 115 LEU B CD2 1 ATOM 6529 N N . LEU B 1 80 ? 42.557 64.974 89.213 1.00 33.17 ? 116 LEU B N 1 ATOM 6530 C CA . LEU B 1 80 ? 42.879 63.726 88.528 1.00 32.33 ? 116 LEU B CA 1 ATOM 6531 C C . LEU B 1 80 ? 42.881 63.917 87.016 1.00 33.21 ? 116 LEU B C 1 ATOM 6532 O O . LEU B 1 80 ? 41.852 64.232 86.430 1.00 33.49 ? 116 LEU B O 1 ATOM 6533 C CB . LEU B 1 80 ? 41.876 62.637 88.884 1.00 30.92 ? 116 LEU B CB 1 ATOM 6534 C CG . LEU B 1 80 ? 41.654 62.410 90.380 1.00 40.21 ? 116 LEU B CG 1 ATOM 6535 C CD1 . LEU B 1 80 ? 40.592 61.334 90.594 1.00 41.28 ? 116 LEU B CD1 1 ATOM 6536 C CD2 . LEU B 1 80 ? 42.975 62.038 91.038 1.00 37.05 ? 116 LEU B CD2 1 ATOM 6537 N N . GLU B 1 81 ? 44.032 63.701 86.390 1.00 32.63 ? 117 GLU B N 1 ATOM 6538 C CA . GLU B 1 81 ? 44.186 63.873 84.951 1.00 32.36 ? 117 GLU B CA 1 ATOM 6539 C C . GLU B 1 81 ? 43.977 62.533 84.257 1.00 34.47 ? 117 GLU B C 1 ATOM 6540 O O . GLU B 1 81 ? 44.593 61.532 84.637 1.00 35.06 ? 117 GLU B O 1 ATOM 6541 C CB . GLU B 1 81 ? 45.592 64.403 84.680 1.00 33.73 ? 117 GLU B CB 1 ATOM 6542 C CG . GLU B 1 81 ? 45.903 64.758 83.241 1.00 35.74 ? 117 GLU B CG 1 ATOM 6543 C CD . GLU B 1 81 ? 47.323 65.283 83.099 1.00 34.66 ? 117 GLU B CD 1 ATOM 6544 O OE1 . GLU B 1 81 ? 48.217 64.484 82.753 1.00 36.95 ? 117 GLU B OE1 1 ATOM 6545 O OE2 . GLU B 1 81 ? 47.550 66.488 83.355 1.00 36.69 ? 117 GLU B OE2 1 ATOM 6546 N N . TYR B 1 82 ? 43.088 62.498 83.271 1.00 28.13 ? 118 TYR B N 1 ATOM 6547 C CA . TYR B 1 82 ? 42.882 61.289 82.463 1.00 32.61 ? 118 TYR B CA 1 ATOM 6548 C C . TYR B 1 82 ? 42.574 61.650 81.007 1.00 34.52 ? 118 TYR B C 1 ATOM 6549 O O . TYR B 1 82 ? 42.550 62.830 80.654 1.00 34.43 ? 118 TYR B O 1 ATOM 6550 C CB . TYR B 1 82 ? 41.790 60.392 83.072 1.00 35.64 ? 118 TYR B CB 1 ATOM 6551 C CG . TYR B 1 82 ? 40.404 61.000 83.065 1.00 35.62 ? 118 TYR B CG 1 ATOM 6552 C CD1 . TYR B 1 82 ? 40.060 62.019 83.942 1.00 34.99 ? 118 TYR B CD1 1 ATOM 6553 C CD2 . TYR B 1 82 ? 39.436 60.545 82.183 1.00 36.59 ? 118 TYR B CD2 1 ATOM 6554 C CE1 . TYR B 1 82 ? 38.784 62.573 83.932 1.00 36.99 ? 118 TYR B CE1 1 ATOM 6555 C CE2 . TYR B 1 82 ? 38.172 61.089 82.161 1.00 39.29 ? 118 TYR B CE2 1 ATOM 6556 C CZ . TYR B 1 82 ? 37.847 62.103 83.033 1.00 41.17 ? 118 TYR B CZ 1 ATOM 6557 O OH . TYR B 1 82 ? 36.576 62.634 82.990 1.00 43.14 ? 118 TYR B OH 1 ATOM 6558 N N . ASN B 1 83 ? 42.358 60.649 80.157 1.00 33.74 ? 119 ASN B N 1 ATOM 6559 C CA . ASN B 1 83 ? 42.218 60.896 78.724 1.00 34.31 ? 119 ASN B CA 1 ATOM 6560 C C . ASN B 1 83 ? 43.333 61.809 78.175 1.00 34.15 ? 119 ASN B C 1 ATOM 6561 O O . ASN B 1 83 ? 43.088 62.689 77.336 1.00 32.80 ? 119 ASN B O 1 ATOM 6562 C CB . ASN B 1 83 ? 40.848 61.505 78.395 1.00 37.28 ? 119 ASN B CB 1 ATOM 6563 C CG . ASN B 1 83 ? 39.690 60.506 78.515 1.00 40.16 ? 119 ASN B CG 1 ATOM 6564 O OD1 . ASN B 1 83 ? 39.862 59.285 78.396 1.00 38.16 ? 119 ASN B OD1 1 ATOM 6565 N ND2 . ASN B 1 83 ? 38.490 61.041 78.736 1.00 43.38 ? 119 ASN B ND2 1 ATOM 6566 N N . TYR B 1 84 ? 44.555 61.613 78.654 1.00 29.66 ? 120 TYR B N 1 ATOM 6567 C CA . TYR B 1 84 ? 45.681 62.402 78.179 1.00 33.24 ? 120 TYR B CA 1 ATOM 6568 C C . TYR B 1 84 ? 45.989 62.072 76.713 1.00 33.34 ? 120 TYR B C 1 ATOM 6569 O O . TYR B 1 84 ? 46.084 60.901 76.344 1.00 33.69 ? 120 TYR B O 1 ATOM 6570 C CB . TYR B 1 84 ? 46.891 62.139 79.065 1.00 31.80 ? 120 TYR B CB 1 ATOM 6571 C CG . TYR B 1 84 ? 48.232 62.548 78.492 1.00 32.97 ? 120 TYR B CG 1 ATOM 6572 C CD1 . TYR B 1 84 ? 48.935 61.704 77.639 1.00 34.04 ? 120 TYR B CD1 1 ATOM 6573 C CD2 . TYR B 1 84 ? 48.820 63.752 78.846 1.00 34.32 ? 120 TYR B CD2 1 ATOM 6574 C CE1 . TYR B 1 84 ? 50.185 62.066 77.133 1.00 35.11 ? 120 TYR B CE1 1 ATOM 6575 C CE2 . TYR B 1 84 ? 50.064 64.122 78.353 1.00 34.92 ? 120 TYR B CE2 1 ATOM 6576 C CZ . TYR B 1 84 ? 50.742 63.279 77.498 1.00 38.00 ? 120 TYR B CZ 1 ATOM 6577 O OH . TYR B 1 84 ? 51.981 63.657 77.008 1.00 46.81 ? 120 TYR B OH 1 ATOM 6578 N N . VAL B 1 85 ? 46.116 63.103 75.881 1.00 30.42 ? 121 VAL B N 1 ATOM 6579 C CA . VAL B 1 85 ? 46.547 62.933 74.485 1.00 30.70 ? 121 VAL B CA 1 ATOM 6580 C C . VAL B 1 85 ? 47.649 63.944 74.215 1.00 29.67 ? 121 VAL B C 1 ATOM 6581 O O . VAL B 1 85 ? 47.424 65.147 74.334 1.00 29.09 ? 121 VAL B O 1 ATOM 6582 C CB . VAL B 1 85 ? 45.399 63.172 73.477 1.00 28.82 ? 121 VAL B CB 1 ATOM 6583 C CG1 . VAL B 1 85 ? 45.908 63.039 72.028 1.00 30.16 ? 121 VAL B CG1 1 ATOM 6584 C CG2 . VAL B 1 85 ? 44.256 62.194 73.726 1.00 32.32 ? 121 VAL B CG2 1 ATOM 6585 N N . LYS B 1 86 ? 48.839 63.456 73.880 1.00 27.13 ? 122 LYS B N 1 ATOM 6586 C CA . LYS B 1 86 ? 50.023 64.304 73.749 1.00 31.32 ? 122 LYS B CA 1 ATOM 6587 C C . LYS B 1 86 ? 49.942 65.169 72.494 1.00 29.15 ? 122 LYS B C 1 ATOM 6588 O O . LYS B 1 86 ? 49.400 64.742 71.478 1.00 28.30 ? 122 LYS B O 1 ATOM 6589 C CB . LYS B 1 86 ? 51.291 63.438 73.690 1.00 29.07 ? 122 LYS B CB 1 ATOM 6590 C CG . LYS B 1 86 ? 52.607 64.212 73.492 1.00 32.75 ? 122 LYS B CG 1 ATOM 6591 C CD . LYS B 1 86 ? 53.795 63.246 73.331 1.00 36.72 ? 122 LYS B CD 1 ATOM 6592 C CE . LYS B 1 86 ? 55.078 63.944 72.819 1.00 34.61 ? 122 LYS B CE 1 ATOM 6593 N NZ . LYS B 1 86 ? 54.949 64.466 71.401 1.00 31.57 ? 122 LYS B NZ 1 ATOM 6594 N N . GLN B 1 87 ? 50.474 66.384 72.565 1.00 26.67 ? 123 GLN B N 1 ATOM 6595 C CA . GLN B 1 87 ? 50.662 67.172 71.344 1.00 29.79 ? 123 GLN B CA 1 ATOM 6596 C C . GLN B 1 87 ? 52.153 67.315 71.012 1.00 27.90 ? 123 GLN B C 1 ATOM 6597 O O . GLN B 1 87 ? 52.744 66.384 70.451 1.00 30.61 ? 123 GLN B O 1 ATOM 6598 C CB . GLN B 1 87 ? 49.946 68.522 71.406 1.00 27.96 ? 123 GLN B CB 1 ATOM 6599 C CG . GLN B 1 87 ? 49.820 69.165 70.046 1.00 29.93 ? 123 GLN B CG 1 ATOM 6600 C CD . GLN B 1 87 ? 49.256 70.571 70.100 1.00 32.93 ? 123 GLN B CD 1 ATOM 6601 O OE1 . GLN B 1 87 ? 49.668 71.399 70.922 1.00 35.66 ? 123 GLN B OE1 1 ATOM 6602 N NE2 . GLN B 1 87 ? 48.297 70.845 69.235 1.00 34.81 ? 123 GLN B NE2 1 ATOM 6603 N N . TRP B 1 88 ? 52.778 68.442 71.354 1.00 24.32 ? 124 TRP B N 1 ATOM 6604 C CA . TRP B 1 88 ? 54.178 68.633 70.962 1.00 25.02 ? 124 TRP B CA 1 ATOM 6605 C C . TRP B 1 88 ? 55.094 68.173 72.093 1.00 28.13 ? 124 TRP B C 1 ATOM 6606 O O . TRP B 1 88 ? 54.762 67.203 72.779 1.00 29.75 ? 124 TRP B O 1 ATOM 6607 C CB . TRP B 1 88 ? 54.464 70.074 70.514 1.00 24.16 ? 124 TRP B CB 1 ATOM 6608 C CG . TRP B 1 88 ? 53.454 70.609 69.512 1.00 26.62 ? 124 TRP B CG 1 ATOM 6609 C CD1 . TRP B 1 88 ? 52.810 71.821 69.556 1.00 24.11 ? 124 TRP B CD1 1 ATOM 6610 C CD2 . TRP B 1 88 ? 52.979 69.946 68.324 1.00 28.62 ? 124 TRP B CD2 1 ATOM 6611 N NE1 . TRP B 1 88 ? 51.959 71.943 68.476 1.00 26.22 ? 124 TRP B NE1 1 ATOM 6612 C CE2 . TRP B 1 88 ? 52.044 70.811 67.707 1.00 23.20 ? 124 TRP B CE2 1 ATOM 6613 C CE3 . TRP B 1 88 ? 53.250 68.708 67.727 1.00 24.39 ? 124 TRP B CE3 1 ATOM 6614 C CZ2 . TRP B 1 88 ? 51.371 70.472 66.537 1.00 26.58 ? 124 TRP B CZ2 1 ATOM 6615 C CZ3 . TRP B 1 88 ? 52.577 68.372 66.549 1.00 28.06 ? 124 TRP B CZ3 1 ATOM 6616 C CH2 . TRP B 1 88 ? 51.654 69.254 65.969 1.00 28.12 ? 124 TRP B CH2 1 ATOM 6617 N N . ARG B 1 89 ? 56.230 68.842 72.305 1.00 24.63 ? 125 ARG B N 1 ATOM 6618 C CA . ARG B 1 89 ? 57.155 68.402 73.360 1.00 26.00 ? 125 ARG B CA 1 ATOM 6619 C C . ARG B 1 89 ? 56.543 68.539 74.756 1.00 23.94 ? 125 ARG B C 1 ATOM 6620 O O . ARG B 1 89 ? 56.728 67.671 75.607 1.00 27.32 ? 125 ARG B O 1 ATOM 6621 C CB . ARG B 1 89 ? 58.489 69.161 73.320 1.00 26.37 ? 125 ARG B CB 1 ATOM 6622 C CG . ARG B 1 89 ? 59.549 68.555 74.264 1.00 26.99 ? 125 ARG B CG 1 ATOM 6623 C CD . ARG B 1 89 ? 60.831 69.369 74.326 1.00 27.14 ? 125 ARG B CD 1 ATOM 6624 N NE . ARG B 1 89 ? 61.427 69.554 73.005 1.00 26.90 ? 125 ARG B NE 1 ATOM 6625 C CZ . ARG B 1 89 ? 62.285 68.708 72.437 1.00 31.29 ? 125 ARG B CZ 1 ATOM 6626 N NH1 . ARG B 1 89 ? 62.660 67.607 73.082 1.00 29.01 ? 125 ARG B NH1 1 ATOM 6627 N NH2 . ARG B 1 89 ? 62.766 68.959 71.218 1.00 29.22 ? 125 ARG B NH2 1 ATOM 6628 N N . HIS B 1 90 ? 55.827 69.633 74.995 1.00 23.97 ? 126 HIS B N 1 ATOM 6629 C CA . HIS B 1 90 ? 55.211 69.866 76.309 1.00 29.08 ? 126 HIS B CA 1 ATOM 6630 C C . HIS B 1 90 ? 53.685 69.859 76.326 1.00 29.54 ? 126 HIS B C 1 ATOM 6631 O O . HIS B 1 90 ? 53.079 69.520 77.339 1.00 30.04 ? 126 HIS B O 1 ATOM 6632 C CB . HIS B 1 90 ? 55.720 71.175 76.911 1.00 27.67 ? 126 HIS B CB 1 ATOM 6633 C CG . HIS B 1 90 ? 57.214 71.282 76.926 1.00 29.74 ? 126 HIS B CG 1 ATOM 6634 N ND1 . HIS B 1 90 ? 58.006 70.528 77.769 1.00 28.54 ? 126 HIS B ND1 1 ATOM 6635 C CD2 . HIS B 1 90 ? 58.062 72.041 76.189 1.00 26.53 ? 126 HIS B CD2 1 ATOM 6636 C CE1 . HIS B 1 90 ? 59.275 70.830 77.559 1.00 28.37 ? 126 HIS B CE1 1 ATOM 6637 N NE2 . HIS B 1 90 ? 59.337 71.738 76.599 1.00 30.14 ? 126 HIS B NE2 1 ATOM 6638 N N . SER B 1 91 ? 53.065 70.233 75.213 1.00 27.38 ? 127 SER B N 1 ATOM 6639 C CA . SER B 1 91 ? 51.622 70.417 75.193 1.00 27.08 ? 127 SER B CA 1 ATOM 6640 C C . SER B 1 91 ? 50.842 69.125 75.102 1.00 27.99 ? 127 SER B C 1 ATOM 6641 O O . SER B 1 91 ? 51.364 68.092 74.673 1.00 25.88 ? 127 SER B O 1 ATOM 6642 C CB . SER B 1 91 ? 51.214 71.329 74.039 1.00 27.12 ? 127 SER B CB 1 ATOM 6643 O OG . SER B 1 91 ? 51.877 70.949 72.852 1.00 29.21 ? 127 SER B OG 1 ATOM 6644 N N . TYR B 1 92 ? 49.571 69.218 75.482 1.00 27.47 ? 128 TYR B N 1 ATOM 6645 C CA . TYR B 1 92 ? 48.638 68.103 75.421 1.00 32.12 ? 128 TYR B CA 1 ATOM 6646 C C . TYR B 1 92 ? 47.257 68.548 75.854 1.00 33.02 ? 128 TYR B C 1 ATOM 6647 O O . TYR B 1 92 ? 47.107 69.648 76.379 1.00 34.08 ? 128 TYR B O 1 ATOM 6648 C CB . TYR B 1 92 ? 49.101 66.948 76.307 1.00 30.17 ? 128 TYR B CB 1 ATOM 6649 C CG . TYR B 1 92 ? 49.188 67.211 77.796 1.00 35.66 ? 128 TYR B CG 1 ATOM 6650 C CD1 . TYR B 1 92 ? 48.073 67.066 78.623 1.00 33.04 ? 128 TYR B CD1 1 ATOM 6651 C CD2 . TYR B 1 92 ? 50.408 67.531 78.389 1.00 39.75 ? 128 TYR B CD2 1 ATOM 6652 C CE1 . TYR B 1 92 ? 48.168 67.265 79.995 1.00 37.64 ? 128 TYR B CE1 1 ATOM 6653 C CE2 . TYR B 1 92 ? 50.515 67.739 79.757 1.00 35.39 ? 128 TYR B CE2 1 ATOM 6654 C CZ . TYR B 1 92 ? 49.396 67.600 80.561 1.00 44.06 ? 128 TYR B CZ 1 ATOM 6655 O OH . TYR B 1 92 ? 49.519 67.800 81.927 1.00 37.36 ? 128 TYR B OH 1 ATOM 6656 N N . THR B 1 93 ? 46.258 67.694 75.628 1.00 29.07 ? 129 THR B N 1 ATOM 6657 C CA . THR B 1 93 ? 44.920 67.906 76.163 1.00 25.19 ? 129 THR B CA 1 ATOM 6658 C C . THR B 1 93 ? 44.561 66.730 77.066 1.00 28.32 ? 129 THR B C 1 ATOM 6659 O O . THR B 1 93 ? 45.059 65.631 76.881 1.00 29.29 ? 129 THR B O 1 ATOM 6660 C CB . THR B 1 93 ? 43.854 68.038 75.060 1.00 25.55 ? 129 THR B CB 1 ATOM 6661 O OG1 . THR B 1 93 ? 43.735 66.798 74.351 1.00 29.05 ? 129 THR B OG1 1 ATOM 6662 C CG2 . THR B 1 93 ? 44.216 69.179 74.047 1.00 25.48 ? 129 THR B CG2 1 ATOM 6663 N N . ALA B 1 94 ? 43.695 66.971 78.042 1.00 25.42 ? 130 ALA B N 1 ATOM 6664 C CA . ALA B 1 94 ? 43.275 65.919 78.949 1.00 29.17 ? 130 ALA B CA 1 ATOM 6665 C C . ALA B 1 94 ? 41.913 66.270 79.514 1.00 28.67 ? 130 ALA B C 1 ATOM 6666 O O . ALA B 1 94 ? 41.443 67.407 79.382 1.00 29.67 ? 130 ALA B O 1 ATOM 6667 C CB . ALA B 1 94 ? 44.293 65.763 80.087 1.00 28.57 ? 130 ALA B CB 1 ATOM 6668 N N . SER B 1 95 ? 41.285 65.281 80.136 1.00 29.12 ? 131 SER B N 1 ATOM 6669 C CA . SER B 1 95 ? 40.091 65.491 80.945 1.00 31.43 ? 131 SER B CA 1 ATOM 6670 C C . SER B 1 95 ? 40.527 65.544 82.406 1.00 30.97 ? 131 SER B C 1 ATOM 6671 O O . SER B 1 95 ? 41.596 65.041 82.750 1.00 31.74 ? 131 SER B O 1 ATOM 6672 C CB . SER B 1 95 ? 39.099 64.353 80.734 1.00 31.55 ? 131 SER B CB 1 ATOM 6673 O OG . SER B 1 95 ? 38.750 64.230 79.363 1.00 34.52 ? 131 SER B OG 1 ATOM 6674 N N . TYR B 1 96 ? 39.703 66.144 83.260 1.00 34.67 ? 132 TYR B N 1 ATOM 6675 C CA . TYR B 1 96 ? 40.058 66.334 84.671 1.00 34.28 ? 132 TYR B CA 1 ATOM 6676 C C . TYR B 1 96 ? 38.845 66.142 85.571 1.00 34.75 ? 132 TYR B C 1 ATOM 6677 O O . TYR B 1 96 ? 37.754 66.649 85.284 1.00 32.49 ? 132 TYR B O 1 ATOM 6678 C CB . TYR B 1 96 ? 40.658 67.732 84.905 1.00 31.52 ? 132 TYR B CB 1 ATOM 6679 C CG . TYR B 1 96 ? 41.999 67.924 84.237 1.00 33.85 ? 132 TYR B CG 1 ATOM 6680 C CD1 . TYR B 1 96 ? 42.079 68.375 82.924 1.00 30.39 ? 132 TYR B CD1 1 ATOM 6681 C CD2 . TYR B 1 96 ? 43.182 67.640 84.908 1.00 29.86 ? 132 TYR B CD2 1 ATOM 6682 C CE1 . TYR B 1 96 ? 43.304 68.532 82.289 1.00 31.02 ? 132 TYR B CE1 1 ATOM 6683 C CE2 . TYR B 1 96 ? 44.410 67.796 84.289 1.00 31.24 ? 132 TYR B CE2 1 ATOM 6684 C CZ . TYR B 1 96 ? 44.463 68.249 82.977 1.00 33.85 ? 132 TYR B CZ 1 ATOM 6685 O OH . TYR B 1 96 ? 45.673 68.412 82.341 1.00 33.53 ? 132 TYR B OH 1 ATOM 6686 N N . ASP B 1 97 ? 39.031 65.381 86.641 1.00 35.25 ? 133 ASP B N 1 ATOM 6687 C CA . ASP B 1 97 ? 38.067 65.366 87.738 1.00 36.13 ? 133 ASP B CA 1 ATOM 6688 C C . ASP B 1 97 ? 38.726 65.953 88.962 1.00 34.68 ? 133 ASP B C 1 ATOM 6689 O O . ASP B 1 97 ? 39.943 65.925 89.083 1.00 37.83 ? 133 ASP B O 1 ATOM 6690 C CB . ASP B 1 97 ? 37.576 63.947 88.031 1.00 39.79 ? 133 ASP B CB 1 ATOM 6691 C CG . ASP B 1 97 ? 36.438 63.524 87.117 1.00 45.64 ? 133 ASP B CG 1 ATOM 6692 O OD1 . ASP B 1 97 ? 35.622 64.393 86.734 1.00 47.58 ? 133 ASP B OD1 1 ATOM 6693 O OD2 . ASP B 1 97 ? 36.357 62.321 86.785 1.00 51.08 ? 133 ASP B OD2 1 ATOM 6694 N N . ILE B 1 98 ? 37.921 66.495 89.869 1.00 35.90 ? 134 ILE B N 1 ATOM 6695 C CA . ILE B 1 98 ? 38.433 67.003 91.138 1.00 38.69 ? 134 ILE B CA 1 ATOM 6696 C C . ILE B 1 98 ? 37.776 66.234 92.285 1.00 41.42 ? 134 ILE B C 1 ATOM 6697 O O . ILE B 1 98 ? 36.559 66.046 92.293 1.00 38.57 ? 134 ILE B O 1 ATOM 6698 C CB . ILE B 1 98 ? 38.161 68.500 91.304 1.00 34.37 ? 134 ILE B CB 1 ATOM 6699 C CG1 . ILE B 1 98 ? 38.613 69.250 90.054 1.00 37.09 ? 134 ILE B CG1 1 ATOM 6700 C CG2 . ILE B 1 98 ? 38.875 69.039 92.530 1.00 33.57 ? 134 ILE B CG2 1 ATOM 6701 C CD1 . ILE B 1 98 ? 38.263 70.702 90.063 1.00 38.65 ? 134 ILE B CD1 1 ATOM 6702 N N . TYR B 1 99 ? 38.592 65.784 93.235 1.00 36.99 ? 135 TYR B N 1 ATOM 6703 C CA . TYR B 1 99 ? 38.134 64.949 94.341 1.00 43.07 ? 135 TYR B CA 1 ATOM 6704 C C . TYR B 1 99 ? 38.307 65.720 95.646 1.00 42.23 ? 135 TYR B C 1 ATOM 6705 O O . TYR B 1 99 ? 39.402 66.172 95.958 1.00 38.38 ? 135 TYR B O 1 ATOM 6706 C CB . TYR B 1 99 ? 38.978 63.678 94.342 1.00 45.25 ? 135 TYR B CB 1 ATOM 6707 C CG . TYR B 1 99 ? 38.665 62.612 95.371 1.00 49.70 ? 135 TYR B CG 1 ATOM 6708 C CD1 . TYR B 1 99 ? 37.654 61.680 95.160 1.00 52.92 ? 135 TYR B CD1 1 ATOM 6709 C CD2 . TYR B 1 99 ? 39.435 62.489 96.523 1.00 52.80 ? 135 TYR B CD2 1 ATOM 6710 C CE1 . TYR B 1 99 ? 37.393 60.672 96.092 1.00 55.14 ? 135 TYR B CE1 1 ATOM 6711 C CE2 . TYR B 1 99 ? 39.183 61.487 97.459 1.00 54.59 ? 135 TYR B CE2 1 ATOM 6712 C CZ . TYR B 1 99 ? 38.164 60.583 97.240 1.00 56.60 ? 135 TYR B CZ 1 ATOM 6713 O OH . TYR B 1 99 ? 37.917 59.595 98.172 1.00 61.11 ? 135 TYR B OH 1 ATOM 6714 N N . ASP B 1 100 ? 37.225 65.892 96.396 1.00 44.46 ? 136 ASP B N 1 ATOM 6715 C CA . ASP B 1 100 ? 37.288 66.626 97.659 1.00 46.85 ? 136 ASP B CA 1 ATOM 6716 C C . ASP B 1 100 ? 37.864 65.735 98.752 1.00 49.39 ? 136 ASP B C 1 ATOM 6717 O O . ASP B 1 100 ? 37.246 64.745 99.138 1.00 50.00 ? 136 ASP B O 1 ATOM 6718 C CB . ASP B 1 100 ? 35.898 67.110 98.075 1.00 46.01 ? 136 ASP B CB 1 ATOM 6719 C CG . ASP B 1 100 ? 35.944 68.101 99.233 1.00 47.28 ? 136 ASP B CG 1 ATOM 6720 O OD1 . ASP B 1 100 ? 36.800 67.961 100.135 1.00 50.08 ? 136 ASP B OD1 1 ATOM 6721 O OD2 . ASP B 1 100 ? 35.126 69.037 99.230 1.00 44.17 ? 136 ASP B OD2 1 ATOM 6722 N N . LEU B 1 101 ? 39.043 66.080 99.254 1.00 45.49 ? 137 LEU B N 1 ATOM 6723 C CA . LEU B 1 101 ? 39.704 65.219 100.227 1.00 45.44 ? 137 LEU B CA 1 ATOM 6724 C C . LEU B 1 101 ? 39.003 65.235 101.583 1.00 51.86 ? 137 LEU B C 1 ATOM 6725 O O . LEU B 1 101 ? 39.055 64.255 102.321 1.00 54.06 ? 137 LEU B O 1 ATOM 6726 C CB . LEU B 1 101 ? 41.186 65.575 100.351 1.00 43.06 ? 137 LEU B CB 1 ATOM 6727 C CG . LEU B 1 101 ? 41.990 65.106 99.138 1.00 42.20 ? 137 LEU B CG 1 ATOM 6728 C CD1 . LEU B 1 101 ? 43.319 65.811 99.030 1.00 38.32 ? 137 LEU B CD1 1 ATOM 6729 C CD2 . LEU B 1 101 ? 42.182 63.610 99.218 1.00 49.69 ? 137 LEU B CD2 1 ATOM 6730 N N . ASN B 1 102 ? 38.338 66.342 101.899 1.00 53.11 ? 138 ASN B N 1 ATOM 6731 C CA . ASN B 1 102 ? 37.630 66.471 103.167 1.00 54.51 ? 138 ASN B CA 1 ATOM 6732 C C . ASN B 1 102 ? 36.331 65.678 103.215 1.00 58.40 ? 138 ASN B C 1 ATOM 6733 O O . ASN B 1 102 ? 36.001 65.094 104.244 1.00 63.56 ? 138 ASN B O 1 ATOM 6734 C CB . ASN B 1 102 ? 37.370 67.941 103.506 1.00 56.86 ? 138 ASN B CB 1 ATOM 6735 C CG . ASN B 1 102 ? 38.477 68.546 104.355 1.00 61.40 ? 138 ASN B CG 1 ATOM 6736 O OD1 . ASN B 1 102 ? 38.594 68.252 105.549 1.00 66.46 ? 138 ASN B OD1 1 ATOM 6737 N ND2 . ASN B 1 102 ? 39.292 69.399 103.745 1.00 56.73 ? 138 ASN B ND2 1 ATOM 6738 N N . LYS B 1 103 ? 35.602 65.655 102.102 1.00 55.61 ? 139 LYS B N 1 ATOM 6739 C CA . LYS B 1 103 ? 34.348 64.914 102.018 1.00 52.51 ? 139 LYS B CA 1 ATOM 6740 C C . LYS B 1 103 ? 34.551 63.542 101.366 1.00 58.79 ? 139 LYS B C 1 ATOM 6741 O O . LYS B 1 103 ? 33.609 62.758 101.237 1.00 65.69 ? 139 LYS B O 1 ATOM 6742 C CB . LYS B 1 103 ? 33.312 65.722 101.228 1.00 54.90 ? 139 LYS B CB 1 ATOM 6743 C CG . LYS B 1 103 ? 33.289 67.214 101.556 1.00 50.94 ? 139 LYS B CG 1 ATOM 6744 N N . ARG B 1 104 ? 35.788 63.258 100.969 1.00 57.15 ? 140 ARG B N 1 ATOM 6745 C CA . ARG B 1 104 ? 36.121 62.067 100.171 1.00 59.33 ? 140 ARG B CA 1 ATOM 6746 C C . ARG B 1 104 ? 35.083 61.723 99.090 1.00 60.56 ? 140 ARG B C 1 ATOM 6747 O O . ARG B 1 104 ? 34.518 60.624 99.073 1.00 60.66 ? 140 ARG B O 1 ATOM 6748 C CB . ARG B 1 104 ? 36.434 60.858 101.065 1.00 60.12 ? 140 ARG B CB 1 ATOM 6749 C CG . ARG B 1 104 ? 37.893 60.789 101.524 1.00 53.99 ? 140 ARG B CG 1 ATOM 6750 N N . GLN B 1 105 ? 34.847 62.676 98.190 1.00 57.60 ? 141 GLN B N 1 ATOM 6751 C CA . GLN B 1 105 ? 33.945 62.470 97.061 1.00 56.81 ? 141 GLN B CA 1 ATOM 6752 C C . GLN B 1 105 ? 34.315 63.375 95.881 1.00 50.31 ? 141 GLN B C 1 ATOM 6753 O O . GLN B 1 105 ? 34.826 64.480 96.080 1.00 42.93 ? 141 GLN B O 1 ATOM 6754 C CB . GLN B 1 105 ? 32.486 62.699 97.481 1.00 57.28 ? 141 GLN B CB 1 ATOM 6755 C CG . GLN B 1 105 ? 32.143 64.134 97.859 1.00 56.74 ? 141 GLN B CG 1 ATOM 6756 C CD . GLN B 1 105 ? 30.658 64.318 98.183 1.00 65.51 ? 141 GLN B CD 1 ATOM 6757 O OE1 . GLN B 1 105 ? 29.908 63.346 98.303 1.00 66.18 ? 141 GLN B OE1 1 ATOM 6758 N NE2 . GLN B 1 105 ? 30.233 65.569 98.322 1.00 59.78 ? 141 GLN B NE2 1 ATOM 6759 N N . LEU B 1 106 ? 34.059 62.892 94.665 1.00 45.23 ? 142 LEU B N 1 ATOM 6760 C CA . LEU B 1 106 ? 34.299 63.668 93.451 1.00 46.31 ? 142 LEU B CA 1 ATOM 6761 C C . LEU B 1 106 ? 33.288 64.790 93.350 1.00 45.12 ? 142 LEU B C 1 ATOM 6762 O O . LEU B 1 106 ? 32.119 64.602 93.676 1.00 46.22 ? 142 LEU B O 1 ATOM 6763 C CB . LEU B 1 106 ? 34.179 62.786 92.205 1.00 45.34 ? 142 LEU B CB 1 ATOM 6764 C CG . LEU B 1 106 ? 35.231 61.709 91.934 1.00 50.36 ? 142 LEU B CG 1 ATOM 6765 C CD1 . LEU B 1 106 ? 34.674 60.630 91.021 1.00 48.22 ? 142 LEU B CD1 1 ATOM 6766 C CD2 . LEU B 1 106 ? 36.499 62.312 91.341 1.00 45.86 ? 142 LEU B CD2 1 ATOM 6767 N N . ILE B 1 107 ? 33.731 65.962 92.909 1.00 44.78 ? 143 ILE B N 1 ATOM 6768 C CA . ILE B 1 107 ? 32.791 67.025 92.587 1.00 44.52 ? 143 ILE B CA 1 ATOM 6769 C C . ILE B 1 107 ? 32.209 66.720 91.205 1.00 50.23 ? 143 ILE B C 1 ATOM 6770 O O . ILE B 1 107 ? 32.945 66.406 90.267 1.00 51.80 ? 143 ILE B O 1 ATOM 6771 C CB . ILE B 1 107 ? 33.432 68.443 92.666 1.00 48.44 ? 143 ILE B CB 1 ATOM 6772 C CG1 . ILE B 1 107 ? 33.910 68.917 91.294 1.00 46.79 ? 143 ILE B CG1 1 ATOM 6773 C CG2 . ILE B 1 107 ? 34.531 68.492 93.743 1.00 39.82 ? 143 ILE B CG2 1 ATOM 6774 N N . THR B 1 108 ? 30.886 66.778 91.091 1.00 44.62 ? 144 THR B N 1 ATOM 6775 C CA . THR B 1 108 ? 30.206 66.290 89.898 1.00 49.19 ? 144 THR B CA 1 ATOM 6776 C C . THR B 1 108 ? 29.457 67.358 89.114 1.00 49.83 ? 144 THR B C 1 ATOM 6777 O O . THR B 1 108 ? 28.801 67.047 88.116 1.00 56.22 ? 144 THR B O 1 ATOM 6778 C CB . THR B 1 108 ? 29.205 65.179 90.246 1.00 52.83 ? 144 THR B CB 1 ATOM 6779 O OG1 . THR B 1 108 ? 28.217 65.697 91.147 1.00 55.35 ? 144 THR B OG1 1 ATOM 6780 C CG2 . THR B 1 108 ? 29.924 63.994 90.886 1.00 49.31 ? 144 THR B CG2 1 ATOM 6781 N N . GLU B 1 109 ? 29.538 68.608 89.552 1.00 46.37 ? 145 GLU B N 1 ATOM 6782 C CA . GLU B 1 109 ? 28.976 69.696 88.754 1.00 50.46 ? 145 GLU B CA 1 ATOM 6783 C C . GLU B 1 109 ? 30.020 70.788 88.530 1.00 49.09 ? 145 GLU B C 1 ATOM 6784 O O . GLU B 1 109 ? 30.978 70.920 89.301 1.00 49.26 ? 145 GLU B O 1 ATOM 6785 C CB . GLU B 1 109 ? 27.721 70.277 89.411 1.00 52.43 ? 145 GLU B CB 1 ATOM 6786 C CG . GLU B 1 109 ? 27.967 70.906 90.780 1.00 51.85 ? 145 GLU B CG 1 ATOM 6787 C CD . GLU B 1 109 ? 26.759 71.680 91.307 1.00 59.27 ? 145 GLU B CD 1 ATOM 6788 O OE1 . GLU B 1 109 ? 26.116 72.416 90.514 1.00 61.37 ? 145 GLU B OE1 1 ATOM 6789 O OE2 . GLU B 1 109 ? 26.456 71.550 92.517 1.00 63.26 ? 145 GLU B OE2 1 ATOM 6790 N N . GLU B 1 110 ? 29.825 71.571 87.476 1.00 50.09 ? 146 GLU B N 1 ATOM 6791 C CA . GLU B 1 110 ? 30.790 72.598 87.100 1.00 47.17 ? 146 GLU B CA 1 ATOM 6792 C C . GLU B 1 110 ? 32.167 71.951 86.911 1.00 42.31 ? 146 GLU B C 1 ATOM 6793 O O . GLU B 1 110 ? 33.192 72.496 87.314 1.00 38.40 ? 146 GLU B O 1 ATOM 6794 C CB . GLU B 1 110 ? 30.834 73.723 88.151 1.00 45.91 ? 146 GLU B CB 1 ATOM 6795 C CG . GLU B 1 110 ? 29.470 74.367 88.445 1.00 49.37 ? 146 GLU B CG 1 ATOM 6796 C CD . GLU B 1 110 ? 28.768 74.883 87.193 1.00 58.61 ? 146 GLU B CD 1 ATOM 6797 O OE1 . GLU B 1 110 ? 29.430 75.561 86.372 1.00 54.81 ? 146 GLU B OE1 1 ATOM 6798 O OE2 . GLU B 1 110 ? 27.555 74.608 87.026 1.00 58.05 ? 146 GLU B OE2 1 ATOM 6799 N N . ARG B 1 111 ? 32.182 70.769 86.308 1.00 38.94 ? 147 ARG B N 1 ATOM 6800 C CA . ARG B 1 111 ? 33.432 70.063 86.102 1.00 37.66 ? 147 ARG B CA 1 ATOM 6801 C C . ARG B 1 111 ? 34.330 70.851 85.150 1.00 38.68 ? 147 ARG B C 1 ATOM 6802 O O . ARG B 1 111 ? 33.844 71.609 84.307 1.00 37.32 ? 147 ARG B O 1 ATOM 6803 C CB . ARG B 1 111 ? 33.165 68.675 85.519 1.00 39.87 ? 147 ARG B CB 1 ATOM 6804 C CG . ARG B 1 111 ? 32.648 67.642 86.515 1.00 43.39 ? 147 ARG B CG 1 ATOM 6805 C CD . ARG B 1 111 ? 32.232 66.387 85.766 1.00 46.98 ? 147 ARG B CD 1 ATOM 6806 N NE . ARG B 1 111 ? 32.384 65.181 86.576 1.00 60.19 ? 147 ARG B NE 1 ATOM 6807 C CZ . ARG B 1 111 ? 32.633 63.971 86.079 1.00 57.91 ? 147 ARG B CZ 1 ATOM 6808 N N . ILE B 1 112 ? 35.638 70.678 85.296 1.00 34.75 ? 148 ILE B N 1 ATOM 6809 C CA . ILE B 1 112 ? 36.594 71.154 84.309 1.00 32.52 ? 148 ILE B CA 1 ATOM 6810 C C . ILE B 1 112 ? 36.284 70.408 83.026 1.00 30.98 ? 148 ILE B C 1 ATOM 6811 O O . ILE B 1 112 ? 36.110 69.192 83.039 1.00 32.14 ? 148 ILE B O 1 ATOM 6812 C CB . ILE B 1 112 ? 38.039 70.883 84.765 1.00 33.42 ? 148 ILE B CB 1 ATOM 6813 C CG1 . ILE B 1 112 ? 38.413 71.860 85.875 1.00 32.05 ? 148 ILE B CG1 1 ATOM 6814 C CG2 . ILE B 1 112 ? 39.029 71.005 83.602 1.00 31.39 ? 148 ILE B CG2 1 ATOM 6815 C CD1 . ILE B 1 112 ? 39.571 71.399 86.714 1.00 37.35 ? 148 ILE B CD1 1 ATOM 6816 N N . PRO B 1 113 ? 36.167 71.139 81.917 1.00 28.95 ? 149 PRO B N 1 ATOM 6817 C CA . PRO B 1 113 ? 35.708 70.510 80.675 1.00 29.40 ? 149 PRO B CA 1 ATOM 6818 C C . PRO B 1 113 ? 36.687 69.482 80.108 1.00 31.50 ? 149 PRO B C 1 ATOM 6819 O O . PRO B 1 113 ? 37.860 69.495 80.472 1.00 30.05 ? 149 PRO B O 1 ATOM 6820 C CB . PRO B 1 113 ? 35.561 71.700 79.715 1.00 29.93 ? 149 PRO B CB 1 ATOM 6821 C CG . PRO B 1 113 ? 36.432 72.767 80.262 1.00 32.33 ? 149 PRO B CG 1 ATOM 6822 C CD . PRO B 1 113 ? 36.372 72.589 81.769 1.00 31.86 ? 149 PRO B CD 1 ATOM 6823 N N . ASN B 1 114 ? 36.212 68.597 79.235 1.00 30.59 ? 150 ASN B N 1 ATOM 6824 C CA . ASN B 1 114 ? 37.116 67.748 78.467 1.00 31.42 ? 150 ASN B CA 1 ATOM 6825 C C . ASN B 1 114 ? 37.910 68.560 77.436 1.00 31.98 ? 150 ASN B C 1 ATOM 6826 O O . ASN B 1 114 ? 37.527 69.664 77.063 1.00 28.84 ? 150 ASN B O 1 ATOM 6827 C CB . ASN B 1 114 ? 36.352 66.646 77.734 1.00 36.89 ? 150 ASN B CB 1 ATOM 6828 C CG . ASN B 1 114 ? 35.617 65.712 78.674 1.00 44.04 ? 150 ASN B CG 1 ATOM 6829 O OD1 . ASN B 1 114 ? 36.100 65.405 79.762 1.00 39.85 ? 150 ASN B OD1 1 ATOM 6830 N ND2 . ASN B 1 114 ? 34.436 65.255 78.250 1.00 50.56 ? 150 ASN B ND2 1 ATOM 6831 N N . ASN B 1 115 ? 38.999 67.976 76.954 1.00 32.02 ? 151 ASN B N 1 ATOM 6832 C CA . ASN B 1 115 ? 39.896 68.644 76.025 1.00 28.47 ? 151 ASN B CA 1 ATOM 6833 C C . ASN B 1 115 ? 40.499 69.906 76.638 1.00 28.07 ? 151 ASN B C 1 ATOM 6834 O O . ASN B 1 115 ? 40.815 70.860 75.938 1.00 31.29 ? 151 ASN B O 1 ATOM 6835 C CB . ASN B 1 115 ? 39.194 68.949 74.697 1.00 30.68 ? 151 ASN B CB 1 ATOM 6836 C CG . ASN B 1 115 ? 38.583 67.708 74.073 1.00 36.71 ? 151 ASN B CG 1 ATOM 6837 O OD1 . ASN B 1 115 ? 39.298 66.842 73.573 1.00 42.28 ? 151 ASN B OD1 1 ATOM 6838 N ND2 . ASN B 1 115 ? 37.258 67.606 74.118 1.00 37.41 ? 151 ASN B ND2 1 ATOM 6839 N N . THR B 1 116 ? 40.667 69.911 77.950 1.00 28.79 ? 152 THR B N 1 ATOM 6840 C CA . THR B 1 116 ? 41.332 71.043 78.582 1.00 28.59 ? 152 THR B CA 1 ATOM 6841 C C . THR B 1 116 ? 42.810 71.013 78.193 1.00 29.29 ? 152 THR B C 1 ATOM 6842 O O . THR B 1 116 ? 43.410 69.945 78.101 1.00 29.36 ? 152 THR B O 1 ATOM 6843 C CB . THR B 1 116 ? 41.129 71.034 80.088 1.00 28.12 ? 152 THR B CB 1 ATOM 6844 O OG1 . THR B 1 116 ? 39.764 71.360 80.358 1.00 29.43 ? 152 THR B OG1 1 ATOM 6845 C CG2 . THR B 1 116 ? 42.010 72.052 80.762 1.00 28.30 ? 152 THR B CG2 1 ATOM 6846 N N . GLN B 1 117 ? 43.370 72.184 77.913 1.00 28.52 ? 153 GLN B N 1 ATOM 6847 C CA . GLN B 1 117 ? 44.727 72.294 77.390 1.00 25.23 ? 153 GLN B CA 1 ATOM 6848 C C . GLN B 1 117 ? 45.766 72.575 78.465 1.00 27.63 ? 153 GLN B C 1 ATOM 6849 O O . GLN B 1 117 ? 46.940 72.235 78.311 1.00 29.16 ? 153 GLN B O 1 ATOM 6850 C CB . GLN B 1 117 ? 44.780 73.401 76.336 1.00 26.74 ? 153 GLN B CB 1 ATOM 6851 C CG . GLN B 1 117 ? 43.942 73.119 75.117 1.00 28.51 ? 153 GLN B CG 1 ATOM 6852 C CD . GLN B 1 117 ? 43.624 74.379 74.360 1.00 33.07 ? 153 GLN B CD 1 ATOM 6853 O OE1 . GLN B 1 117 ? 42.927 75.257 74.872 1.00 30.47 ? 153 GLN B OE1 1 ATOM 6854 N NE2 . GLN B 1 117 ? 44.140 74.486 73.136 1.00 27.77 ? 153 GLN B NE2 1 ATOM 6855 N N . TRP B 1 118 ? 45.343 73.195 79.559 1.00 27.86 ? 154 TRP B N 1 ATOM 6856 C CA . TRP B 1 118 ? 46.241 73.410 80.692 1.00 27.35 ? 154 TRP B CA 1 ATOM 6857 C C . TRP B 1 118 ? 45.428 73.732 81.941 1.00 30.09 ? 154 TRP B C 1 ATOM 6858 O O . TRP B 1 118 ? 44.438 74.450 81.854 1.00 31.03 ? 154 TRP B O 1 ATOM 6859 C CB . TRP B 1 118 ? 47.222 74.551 80.398 1.00 25.99 ? 154 TRP B CB 1 ATOM 6860 C CG . TRP B 1 118 ? 48.138 74.839 81.557 1.00 31.01 ? 154 TRP B CG 1 ATOM 6861 C CD1 . TRP B 1 118 ? 48.099 75.928 82.394 1.00 33.35 ? 154 TRP B CD1 1 ATOM 6862 C CD2 . TRP B 1 118 ? 49.206 74.009 82.032 1.00 30.08 ? 154 TRP B CD2 1 ATOM 6863 N NE1 . TRP B 1 118 ? 49.095 75.831 83.342 1.00 30.29 ? 154 TRP B NE1 1 ATOM 6864 C CE2 . TRP B 1 118 ? 49.786 74.664 83.142 1.00 32.59 ? 154 TRP B CE2 1 ATOM 6865 C CE3 . TRP B 1 118 ? 49.737 72.783 81.620 1.00 33.68 ? 154 TRP B CE3 1 ATOM 6866 C CZ2 . TRP B 1 118 ? 50.864 74.128 83.849 1.00 35.42 ? 154 TRP B CZ2 1 ATOM 6867 C CZ3 . TRP B 1 118 ? 50.814 72.256 82.320 1.00 37.18 ? 154 TRP B CZ3 1 ATOM 6868 C CH2 . TRP B 1 118 ? 51.362 72.929 83.422 1.00 35.42 ? 154 TRP B CH2 1 ATOM 6869 N N . VAL B 1 119 ? 45.833 73.176 83.085 1.00 30.64 ? 155 VAL B N 1 ATOM 6870 C CA . VAL B 1 119 ? 45.204 73.462 84.380 1.00 29.80 ? 155 VAL B CA 1 ATOM 6871 C C . VAL B 1 119 ? 46.283 73.676 85.424 1.00 30.56 ? 155 VAL B C 1 ATOM 6872 O O . VAL B 1 119 ? 47.289 72.961 85.437 1.00 32.07 ? 155 VAL B O 1 ATOM 6873 C CB . VAL B 1 119 ? 44.385 72.273 84.935 1.00 32.13 ? 155 VAL B CB 1 ATOM 6874 C CG1 . VAL B 1 119 ? 43.440 72.764 86.032 1.00 32.99 ? 155 VAL B CG1 1 ATOM 6875 C CG2 . VAL B 1 119 ? 43.624 71.557 83.857 1.00 33.21 ? 155 VAL B CG2 1 ATOM 6876 N N . THR B 1 120 ? 46.078 74.634 86.319 1.00 29.04 ? 156 THR B N 1 ATOM 6877 C CA . THR B 1 120 ? 46.981 74.764 87.453 1.00 30.49 ? 156 THR B CA 1 ATOM 6878 C C . THR B 1 120 ? 46.302 75.328 88.708 1.00 31.50 ? 156 THR B C 1 ATOM 6879 O O . THR B 1 120 ? 45.483 76.241 88.626 1.00 27.91 ? 156 THR B O 1 ATOM 6880 C CB . THR B 1 120 ? 48.231 75.588 87.105 1.00 35.15 ? 156 THR B CB 1 ATOM 6881 O OG1 . THR B 1 120 ? 49.109 75.605 88.238 1.00 32.45 ? 156 THR B OG1 1 ATOM 6882 C CG2 . THR B 1 120 ? 47.858 77.021 86.730 1.00 30.58 ? 156 THR B CG2 1 ATOM 6883 N N . TRP B 1 121 ? 46.637 74.762 89.863 1.00 28.01 ? 157 TRP B N 1 ATOM 6884 C CA . TRP B 1 121 ? 46.235 75.347 91.150 1.00 31.85 ? 157 TRP B CA 1 ATOM 6885 C C . TRP B 1 121 ? 46.936 76.684 91.349 1.00 31.10 ? 157 TRP B C 1 ATOM 6886 O O . TRP B 1 121 ? 48.011 76.899 90.809 1.00 29.27 ? 157 TRP B O 1 ATOM 6887 C CB . TRP B 1 121 ? 46.648 74.432 92.317 1.00 31.07 ? 157 TRP B CB 1 ATOM 6888 C CG . TRP B 1 121 ? 45.929 73.105 92.370 1.00 30.58 ? 157 TRP B CG 1 ATOM 6889 C CD1 . TRP B 1 121 ? 46.452 71.873 92.099 1.00 27.67 ? 157 TRP B CD1 1 ATOM 6890 C CD2 . TRP B 1 121 ? 44.559 72.892 92.707 1.00 27.21 ? 157 TRP B CD2 1 ATOM 6891 N NE1 . TRP B 1 121 ? 45.491 70.906 92.256 1.00 25.14 ? 157 TRP B NE1 1 ATOM 6892 C CE2 . TRP B 1 121 ? 44.315 71.507 92.611 1.00 28.99 ? 157 TRP B CE2 1 ATOM 6893 C CE3 . TRP B 1 121 ? 43.512 73.737 93.077 1.00 31.07 ? 157 TRP B CE3 1 ATOM 6894 C CZ2 . TRP B 1 121 ? 43.068 70.948 92.881 1.00 33.38 ? 157 TRP B CZ2 1 ATOM 6895 C CZ3 . TRP B 1 121 ? 42.270 73.180 93.343 1.00 33.51 ? 157 TRP B CZ3 1 ATOM 6896 C CH2 . TRP B 1 121 ? 42.060 71.803 93.251 1.00 32.24 ? 157 TRP B CH2 1 ATOM 6897 N N . SER B 1 122 ? 46.349 77.568 92.151 1.00 35.49 ? 158 SER B N 1 ATOM 6898 C CA . SER B 1 122 ? 47.074 78.734 92.651 1.00 32.49 ? 158 SER B CA 1 ATOM 6899 C C . SER B 1 122 ? 48.194 78.232 93.566 1.00 36.17 ? 158 SER B C 1 ATOM 6900 O O . SER B 1 122 ? 48.175 77.069 93.958 1.00 37.62 ? 158 SER B O 1 ATOM 6901 C CB . SER B 1 122 ? 46.118 79.658 93.414 1.00 35.20 ? 158 SER B CB 1 ATOM 6902 O OG . SER B 1 122 ? 45.291 78.922 94.308 1.00 36.36 ? 158 SER B OG 1 ATOM 6903 N N . PRO B 1 123 ? 49.176 79.096 93.902 1.00 34.81 ? 159 PRO B N 1 ATOM 6904 C CA . PRO B 1 123 ? 50.333 78.687 94.715 1.00 35.77 ? 159 PRO B CA 1 ATOM 6905 C C . PRO B 1 123 ? 49.984 78.491 96.198 1.00 39.77 ? 159 PRO B C 1 ATOM 6906 O O . PRO B 1 123 ? 50.699 77.788 96.910 1.00 38.19 ? 159 PRO B O 1 ATOM 6907 C CB . PRO B 1 123 ? 51.315 79.862 94.567 1.00 34.62 ? 159 PRO B CB 1 ATOM 6908 C CG . PRO B 1 123 ? 50.762 80.715 93.462 1.00 35.43 ? 159 PRO B CG 1 ATOM 6909 C CD . PRO B 1 123 ? 49.285 80.496 93.467 1.00 33.20 ? 159 PRO B CD 1 ATOM 6910 N N . VAL B 1 124 ? 48.908 79.131 96.648 1.00 36.89 ? 160 VAL B N 1 ATOM 6911 C CA . VAL B 1 124 ? 48.338 78.884 97.967 1.00 38.62 ? 160 VAL B CA 1 ATOM 6912 C C . VAL B 1 124 ? 46.837 78.670 97.801 1.00 41.05 ? 160 VAL B C 1 ATOM 6913 O O . VAL B 1 124 ? 46.243 79.152 96.840 1.00 40.26 ? 160 VAL B O 1 ATOM 6914 C CB . VAL B 1 124 ? 48.571 80.068 98.921 1.00 41.81 ? 160 VAL B CB 1 ATOM 6915 C CG1 . VAL B 1 124 ? 50.057 80.367 99.049 1.00 37.27 ? 160 VAL B CG1 1 ATOM 6916 C CG2 . VAL B 1 124 ? 47.812 81.293 98.437 1.00 40.28 ? 160 VAL B CG2 1 ATOM 6917 N N . GLY B 1 125 ? 46.217 77.933 98.713 1.00 35.75 ? 161 GLY B N 1 ATOM 6918 C CA . GLY B 1 125 ? 44.776 77.770 98.651 1.00 39.78 ? 161 GLY B CA 1 ATOM 6919 C C . GLY B 1 125 ? 44.340 76.696 97.676 1.00 39.76 ? 161 GLY B C 1 ATOM 6920 O O . GLY B 1 125 ? 44.975 75.647 97.599 1.00 38.00 ? 161 GLY B O 1 ATOM 6921 N N . HIS B 1 126 ? 43.255 76.954 96.945 1.00 38.25 ? 162 HIS B N 1 ATOM 6922 C CA . HIS B 1 126 ? 42.756 76.030 95.931 1.00 35.35 ? 162 HIS B CA 1 ATOM 6923 C C . HIS B 1 126 ? 42.003 76.714 94.797 1.00 33.36 ? 162 HIS B C 1 ATOM 6924 O O . HIS B 1 126 ? 41.008 76.178 94.317 1.00 34.56 ? 162 HIS B O 1 ATOM 6925 C CB . HIS B 1 126 ? 41.840 74.966 96.545 1.00 37.46 ? 162 HIS B CB 1 ATOM 6926 C CG . HIS B 1 126 ? 40.813 75.524 97.480 1.00 42.80 ? 162 HIS B CG 1 ATOM 6927 N ND1 . HIS B 1 126 ? 40.991 75.560 98.847 1.00 45.01 ? 162 HIS B ND1 1 ATOM 6928 C CD2 . HIS B 1 126 ? 39.603 76.084 97.244 1.00 43.36 ? 162 HIS B CD2 1 ATOM 6929 C CE1 . HIS B 1 126 ? 39.932 76.112 99.413 1.00 47.21 ? 162 HIS B CE1 1 ATOM 6930 N NE2 . HIS B 1 126 ? 39.074 76.439 98.463 1.00 48.51 ? 162 HIS B NE2 1 ATOM 6931 N N . LYS B 1 127 ? 42.463 77.882 94.354 1.00 32.56 ? 163 LYS B N 1 ATOM 6932 C CA . LYS B 1 127 ? 41.915 78.442 93.117 1.00 36.14 ? 163 LYS B CA 1 ATOM 6933 C C . LYS B 1 127 ? 42.420 77.595 91.957 1.00 33.19 ? 163 LYS B C 1 ATOM 6934 O O . LYS B 1 127 ? 43.435 76.921 92.091 1.00 33.65 ? 163 LYS B O 1 ATOM 6935 C CB . LYS B 1 127 ? 42.325 79.902 92.916 1.00 37.05 ? 163 LYS B CB 1 ATOM 6936 C CG . LYS B 1 127 ? 41.720 80.867 93.935 1.00 38.35 ? 163 LYS B CG 1 ATOM 6937 C CD . LYS B 1 127 ? 42.084 82.302 93.612 1.00 38.45 ? 163 LYS B CD 1 ATOM 6938 C CE . LYS B 1 127 ? 41.659 83.222 94.738 1.00 45.16 ? 163 LYS B CE 1 ATOM 6939 N NZ . LYS B 1 127 ? 42.284 84.563 94.676 1.00 44.61 ? 163 LYS B NZ 1 ATOM 6940 N N . LEU B 1 128 ? 41.703 77.621 90.837 1.00 34.88 ? 164 LEU B N 1 ATOM 6941 C CA . LEU B 1 128 ? 42.113 76.914 89.621 1.00 31.76 ? 164 LEU B CA 1 ATOM 6942 C C . LEU B 1 128 ? 42.115 77.875 88.452 1.00 33.05 ? 164 LEU B C 1 ATOM 6943 O O . LEU B 1 128 ? 41.226 78.714 88.335 1.00 32.23 ? 164 LEU B O 1 ATOM 6944 C CB . LEU B 1 128 ? 41.131 75.791 89.295 1.00 31.70 ? 164 LEU B CB 1 ATOM 6945 C CG . LEU B 1 128 ? 41.288 74.448 90.000 1.00 34.92 ? 164 LEU B CG 1 ATOM 6946 C CD1 . LEU B 1 128 ? 40.063 73.587 89.740 1.00 35.45 ? 164 LEU B CD1 1 ATOM 6947 C CD2 . LEU B 1 128 ? 42.544 73.736 89.540 1.00 31.43 ? 164 LEU B CD2 1 ATOM 6948 N N . ALA B 1 129 ? 43.117 77.767 87.590 1.00 31.05 ? 165 ALA B N 1 ATOM 6949 C CA . ALA B 1 129 ? 43.062 78.428 86.295 1.00 33.60 ? 165 ALA B CA 1 ATOM 6950 C C . ALA B 1 129 ? 43.197 77.329 85.251 1.00 30.67 ? 165 ALA B C 1 ATOM 6951 O O . ALA B 1 129 ? 44.030 76.438 85.399 1.00 30.22 ? 165 ALA B O 1 ATOM 6952 C CB . ALA B 1 129 ? 44.186 79.468 86.151 1.00 26.89 ? 165 ALA B CB 1 ATOM 6953 N N . TYR B 1 130 ? 42.357 77.358 84.225 1.00 29.41 ? 166 TYR B N 1 ATOM 6954 C CA . TYR B 1 130 ? 42.522 76.415 83.127 1.00 30.08 ? 166 TYR B CA 1 ATOM 6955 C C . TYR B 1 130 ? 42.350 77.073 81.766 1.00 29.13 ? 166 TYR B C 1 ATOM 6956 O O . TYR B 1 130 ? 41.787 78.165 81.661 1.00 31.20 ? 166 TYR B O 1 ATOM 6957 C CB . TYR B 1 130 ? 41.616 75.190 83.301 1.00 31.07 ? 166 TYR B CB 1 ATOM 6958 C CG . TYR B 1 130 ? 40.130 75.445 83.265 1.00 30.23 ? 166 TYR B CG 1 ATOM 6959 C CD1 . TYR B 1 130 ? 39.405 75.658 84.429 1.00 32.91 ? 166 TYR B CD1 1 ATOM 6960 C CD2 . TYR B 1 130 ? 39.448 75.448 82.067 1.00 33.29 ? 166 TYR B CD2 1 ATOM 6961 C CE1 . TYR B 1 130 ? 38.037 75.883 84.384 1.00 34.09 ? 166 TYR B CE1 1 ATOM 6962 C CE2 . TYR B 1 130 ? 38.091 75.666 82.014 1.00 34.76 ? 166 TYR B CE2 1 ATOM 6963 C CZ . TYR B 1 130 ? 37.391 75.880 83.168 1.00 34.57 ? 166 TYR B CZ 1 ATOM 6964 O OH . TYR B 1 130 ? 36.037 76.099 83.079 1.00 37.65 ? 166 TYR B OH 1 ATOM 6965 N N . VAL B 1 131 ? 42.872 76.419 80.737 1.00 28.17 ? 167 VAL B N 1 ATOM 6966 C CA . VAL B 1 131 ? 42.712 76.883 79.366 1.00 26.72 ? 167 VAL B CA 1 ATOM 6967 C C . VAL B 1 131 ? 41.921 75.837 78.576 1.00 28.86 ? 167 VAL B C 1 ATOM 6968 O O . VAL B 1 131 ? 42.234 74.645 78.593 1.00 27.92 ? 167 VAL B O 1 ATOM 6969 C CB . VAL B 1 131 ? 44.066 77.166 78.701 1.00 26.70 ? 167 VAL B CB 1 ATOM 6970 C CG1 . VAL B 1 131 ? 43.879 77.527 77.219 1.00 26.88 ? 167 VAL B CG1 1 ATOM 6971 C CG2 . VAL B 1 131 ? 44.777 78.281 79.429 1.00 26.77 ? 167 VAL B CG2 1 ATOM 6972 N N . TRP B 1 132 ? 40.858 76.289 77.936 1.00 26.08 ? 168 TRP B N 1 ATOM 6973 C CA . TRP B 1 132 ? 39.991 75.426 77.161 1.00 27.73 ? 168 TRP B CA 1 ATOM 6974 C C . TRP B 1 132 ? 39.607 76.213 75.905 1.00 31.09 ? 168 TRP B C 1 ATOM 6975 O O . TRP B 1 132 ? 39.207 77.367 76.006 1.00 31.33 ? 168 TRP B O 1 ATOM 6976 C CB . TRP B 1 132 ? 38.750 75.063 77.968 1.00 27.08 ? 168 TRP B CB 1 ATOM 6977 C CG . TRP B 1 132 ? 37.785 74.175 77.237 1.00 30.95 ? 168 TRP B CG 1 ATOM 6978 C CD1 . TRP B 1 132 ? 37.941 72.844 76.954 1.00 29.89 ? 168 TRP B CD1 1 ATOM 6979 C CD2 . TRP B 1 132 ? 36.497 74.542 76.736 1.00 31.76 ? 168 TRP B CD2 1 ATOM 6980 N NE1 . TRP B 1 132 ? 36.838 72.371 76.281 1.00 30.27 ? 168 TRP B NE1 1 ATOM 6981 C CE2 . TRP B 1 132 ? 35.934 73.391 76.143 1.00 34.67 ? 168 TRP B CE2 1 ATOM 6982 C CE3 . TRP B 1 132 ? 35.763 75.734 76.730 1.00 36.40 ? 168 TRP B CE3 1 ATOM 6983 C CZ2 . TRP B 1 132 ? 34.671 73.398 75.546 1.00 38.01 ? 168 TRP B CZ2 1 ATOM 6984 C CZ3 . TRP B 1 132 ? 34.508 75.739 76.134 1.00 40.59 ? 168 TRP B CZ3 1 ATOM 6985 C CH2 . TRP B 1 132 ? 33.977 74.579 75.550 1.00 41.52 ? 168 TRP B CH2 1 ATOM 6986 N N . ASN B 1 133 ? 39.761 75.595 74.736 1.00 31.59 ? 169 ASN B N 1 ATOM 6987 C CA . ASN B 1 133 ? 39.581 76.294 73.459 1.00 33.89 ? 169 ASN B CA 1 ATOM 6988 C C . ASN B 1 133 ? 40.378 77.601 73.381 1.00 32.60 ? 169 ASN B C 1 ATOM 6989 O O . ASN B 1 133 ? 39.889 78.596 72.855 1.00 33.87 ? 169 ASN B O 1 ATOM 6990 C CB . ASN B 1 133 ? 38.103 76.565 73.172 1.00 32.78 ? 169 ASN B CB 1 ATOM 6991 C CG . ASN B 1 133 ? 37.332 75.303 72.825 1.00 40.21 ? 169 ASN B CG 1 ATOM 6992 O OD1 . ASN B 1 133 ? 36.115 75.252 72.973 1.00 45.78 ? 169 ASN B OD1 1 ATOM 6993 N ND2 . ASN B 1 133 ? 38.037 74.278 72.377 1.00 38.00 ? 169 ASN B ND2 1 ATOM 6994 N N . ASN B 1 134 ? 41.605 77.591 73.898 1.00 28.86 ? 170 ASN B N 1 ATOM 6995 C CA . ASN B 1 134 ? 42.485 78.757 73.789 1.00 29.62 ? 170 ASN B CA 1 ATOM 6996 C C . ASN B 1 134 ? 42.059 79.969 74.628 1.00 28.62 ? 170 ASN B C 1 ATOM 6997 O O . ASN B 1 134 ? 42.576 81.063 74.422 1.00 30.13 ? 170 ASN B O 1 ATOM 6998 C CB . ASN B 1 134 ? 42.654 79.183 72.317 1.00 27.49 ? 170 ASN B CB 1 ATOM 6999 C CG . ASN B 1 134 ? 43.539 78.227 71.523 1.00 31.77 ? 170 ASN B CG 1 ATOM 7000 O OD1 . ASN B 1 134 ? 43.539 77.015 71.754 1.00 28.69 ? 170 ASN B OD1 1 ATOM 7001 N ND2 . ASN B 1 134 ? 44.296 78.772 70.576 1.00 29.02 ? 170 ASN B ND2 1 ATOM 7002 N N . ASP B 1 135 ? 41.111 79.778 75.545 1.00 26.22 ? 171 ASP B N 1 ATOM 7003 C CA . ASP B 1 135 ? 40.676 80.841 76.460 1.00 30.24 ? 171 ASP B CA 1 ATOM 7004 C C . ASP B 1 135 ? 40.890 80.457 77.916 1.00 30.16 ? 171 ASP B C 1 ATOM 7005 O O . ASP B 1 135 ? 40.880 79.276 78.252 1.00 28.27 ? 171 ASP B O 1 ATOM 7006 C CB . ASP B 1 135 ? 39.207 81.192 76.239 1.00 30.62 ? 171 ASP B CB 1 ATOM 7007 C CG . ASP B 1 135 ? 39.020 82.198 75.118 1.00 34.88 ? 171 ASP B CG 1 ATOM 7008 O OD1 . ASP B 1 135 ? 39.833 83.149 75.043 1.00 33.82 ? 171 ASP B OD1 1 ATOM 7009 O OD2 . ASP B 1 135 ? 38.082 82.027 74.311 1.00 35.14 ? 171 ASP B OD2 1 ATOM 7010 N N . ILE B 1 136 ? 41.074 81.467 78.765 1.00 29.19 ? 172 ILE B N 1 ATOM 7011 C CA . ILE B 1 136 ? 41.377 81.265 80.168 1.00 28.73 ? 172 ILE B CA 1 ATOM 7012 C C . ILE B 1 136 ? 40.111 81.313 81.017 1.00 33.41 ? 172 ILE B C 1 ATOM 7013 O O . ILE B 1 136 ? 39.231 82.133 80.785 1.00 32.52 ? 172 ILE B O 1 ATOM 7014 C CB . ILE B 1 136 ? 42.356 82.323 80.683 1.00 26.83 ? 172 ILE B CB 1 ATOM 7015 C CG1 . ILE B 1 136 ? 43.686 82.215 79.939 1.00 26.19 ? 172 ILE B CG1 1 ATOM 7016 C CG2 . ILE B 1 136 ? 42.553 82.173 82.195 1.00 27.68 ? 172 ILE B CG2 1 ATOM 7017 C CD1 . ILE B 1 136 ? 44.591 83.389 80.140 1.00 28.59 ? 172 ILE B CD1 1 ATOM 7018 N N . TYR B 1 137 ? 40.033 80.410 81.989 1.00 29.58 ? 173 TYR B N 1 ATOM 7019 C CA . TYR B 1 137 ? 38.897 80.310 82.891 1.00 33.41 ? 173 TYR B CA 1 ATOM 7020 C C . TYR B 1 137 ? 39.426 80.179 84.320 1.00 32.84 ? 173 TYR B C 1 ATOM 7021 O O . TYR B 1 137 ? 40.489 79.601 84.537 1.00 34.33 ? 173 TYR B O 1 ATOM 7022 C CB . TYR B 1 137 ? 38.031 79.090 82.542 1.00 33.03 ? 173 TYR B CB 1 ATOM 7023 C CG . TYR B 1 137 ? 37.309 79.182 81.221 1.00 35.18 ? 173 TYR B CG 1 ATOM 7024 C CD1 . TYR B 1 137 ? 37.954 78.863 80.035 1.00 31.51 ? 173 TYR B CD1 1 ATOM 7025 C CD2 . TYR B 1 137 ? 35.978 79.572 81.158 1.00 35.41 ? 173 TYR B CD2 1 ATOM 7026 C CE1 . TYR B 1 137 ? 37.311 78.940 78.820 1.00 33.65 ? 173 TYR B CE1 1 ATOM 7027 C CE2 . TYR B 1 137 ? 35.316 79.656 79.933 1.00 36.64 ? 173 TYR B CE2 1 ATOM 7028 C CZ . TYR B 1 137 ? 35.995 79.341 78.764 1.00 34.59 ? 173 TYR B CZ 1 ATOM 7029 O OH . TYR B 1 137 ? 35.367 79.408 77.535 1.00 35.70 ? 173 TYR B OH 1 ATOM 7030 N N . VAL B 1 138 ? 38.700 80.725 85.291 1.00 33.56 ? 174 VAL B N 1 ATOM 7031 C CA . VAL B 1 138 ? 39.109 80.633 86.690 1.00 30.41 ? 174 VAL B CA 1 ATOM 7032 C C . VAL B 1 138 ? 37.983 80.097 87.565 1.00 33.33 ? 174 VAL B C 1 ATOM 7033 O O . VAL B 1 138 ? 36.835 80.519 87.444 1.00 35.78 ? 174 VAL B O 1 ATOM 7034 C CB . VAL B 1 138 ? 39.544 82.000 87.255 1.00 34.87 ? 174 VAL B CB 1 ATOM 7035 C CG1 . VAL B 1 138 ? 39.794 81.882 88.744 1.00 34.92 ? 174 VAL B CG1 1 ATOM 7036 C CG2 . VAL B 1 138 ? 40.787 82.497 86.551 1.00 35.76 ? 174 VAL B CG2 1 ATOM 7037 N N . LYS B 1 139 ? 38.323 79.158 88.436 1.00 32.53 ? 175 LYS B N 1 ATOM 7038 C CA . LYS B 1 139 ? 37.402 78.633 89.426 1.00 34.17 ? 175 LYS B CA 1 ATOM 7039 C C . LYS B 1 139 ? 37.904 79.042 90.796 1.00 36.31 ? 175 LYS B C 1 ATOM 7040 O O . LYS B 1 139 ? 39.006 78.659 91.193 1.00 37.82 ? 175 LYS B O 1 ATOM 7041 C CB . LYS B 1 139 ? 37.372 77.110 89.364 1.00 34.63 ? 175 LYS B CB 1 ATOM 7042 C CG . LYS B 1 139 ? 36.369 76.534 88.421 1.00 37.10 ? 175 LYS B CG 1 ATOM 7043 C CD . LYS B 1 139 ? 36.479 75.034 88.444 1.00 40.01 ? 175 LYS B CD 1 ATOM 7044 C CE . LYS B 1 139 ? 35.246 74.390 87.870 1.00 43.93 ? 175 LYS B CE 1 ATOM 7045 N NZ . LYS B 1 139 ? 34.199 74.247 88.915 1.00 46.02 ? 175 LYS B NZ 1 ATOM 7046 N N . ILE B 1 140 ? 37.113 79.823 91.522 1.00 38.18 ? 176 ILE B N 1 ATOM 7047 C CA . ILE B 1 140 ? 37.507 80.235 92.865 1.00 40.28 ? 176 ILE B CA 1 ATOM 7048 C C . ILE B 1 140 ? 37.383 79.060 93.839 1.00 41.49 ? 176 ILE B C 1 ATOM 7049 O O . ILE B 1 140 ? 38.200 78.900 94.741 1.00 44.20 ? 176 ILE B O 1 ATOM 7050 C CB . ILE B 1 140 ? 36.665 81.419 93.356 1.00 43.59 ? 176 ILE B CB 1 ATOM 7051 C CG1 . ILE B 1 140 ? 36.879 82.630 92.444 1.00 38.80 ? 176 ILE B CG1 1 ATOM 7052 C CG2 . ILE B 1 140 ? 37.017 81.750 94.783 1.00 41.61 ? 176 ILE B CG2 1 ATOM 7053 C CD1 . ILE B 1 140 ? 38.335 83.068 92.337 1.00 37.46 ? 176 ILE B CD1 1 ATOM 7054 N N . GLU B 1 141 ? 36.361 78.235 93.637 1.00 39.20 ? 177 GLU B N 1 ATOM 7055 C CA . GLU B 1 141 ? 36.199 77.001 94.394 1.00 42.71 ? 177 GLU B CA 1 ATOM 7056 C C . GLU B 1 141 ? 35.919 75.875 93.406 1.00 41.99 ? 177 GLU B C 1 ATOM 7057 O O . GLU B 1 141 ? 35.244 76.086 92.407 1.00 42.26 ? 177 GLU B O 1 ATOM 7058 C CB . GLU B 1 141 ? 35.032 77.123 95.384 1.00 48.40 ? 177 GLU B CB 1 ATOM 7059 C CG . GLU B 1 141 ? 35.118 78.316 96.345 1.00 48.82 ? 177 GLU B CG 1 ATOM 7060 C CD . GLU B 1 141 ? 36.135 78.114 97.455 1.00 53.14 ? 177 GLU B CD 1 ATOM 7061 O OE1 . GLU B 1 141 ? 36.495 76.947 97.731 1.00 51.52 ? 177 GLU B OE1 1 ATOM 7062 O OE2 . GLU B 1 141 ? 36.578 79.125 98.054 1.00 57.68 ? 177 GLU B OE2 1 ATOM 7063 N N . PRO B 1 142 ? 36.435 74.671 93.679 1.00 42.28 ? 178 PRO B N 1 ATOM 7064 C CA . PRO B 1 142 ? 36.282 73.532 92.761 1.00 41.86 ? 178 PRO B CA 1 ATOM 7065 C C . PRO B 1 142 ? 34.842 73.222 92.329 1.00 46.48 ? 178 PRO B C 1 ATOM 7066 O O . PRO B 1 142 ? 34.641 72.676 91.244 1.00 44.15 ? 178 PRO B O 1 ATOM 7067 C CB . PRO B 1 142 ? 36.863 72.365 93.564 1.00 39.69 ? 178 PRO B CB 1 ATOM 7068 C CG . PRO B 1 142 ? 37.902 73.006 94.431 1.00 37.15 ? 178 PRO B CG 1 ATOM 7069 C CD . PRO B 1 142 ? 37.328 74.355 94.808 1.00 43.16 ? 178 PRO B CD 1 ATOM 7070 N N . ASN B 1 143 ? 33.856 73.566 93.148 1.00 46.28 ? 179 ASN B N 1 ATOM 7071 C CA . ASN B 1 143 ? 32.471 73.203 92.845 1.00 46.76 ? 179 ASN B CA 1 ATOM 7072 C C . ASN B 1 143 ? 31.659 74.337 92.231 1.00 46.07 ? 179 ASN B C 1 ATOM 7073 O O . ASN B 1 143 ? 30.535 74.124 91.780 1.00 51.13 ? 179 ASN B O 1 ATOM 7074 C CB . ASN B 1 143 ? 31.768 72.712 94.107 1.00 50.13 ? 179 ASN B CB 1 ATOM 7075 C CG . ASN B 1 143 ? 31.808 73.734 95.216 1.00 47.84 ? 179 ASN B CG 1 ATOM 7076 O OD1 . ASN B 1 143 ? 30.962 74.617 95.290 1.00 55.80 ? 179 ASN B OD1 1 ATOM 7077 N ND2 . ASN B 1 143 ? 32.812 73.633 96.075 1.00 57.89 ? 179 ASN B ND2 1 ATOM 7078 N N . LEU B 1 144 ? 32.219 75.541 92.225 1.00 43.31 ? 180 LEU B N 1 ATOM 7079 C CA . LEU B 1 144 ? 31.512 76.707 91.696 1.00 48.53 ? 180 LEU B CA 1 ATOM 7080 C C . LEU B 1 144 ? 31.752 76.898 90.199 1.00 47.20 ? 180 LEU B C 1 ATOM 7081 O O . LEU B 1 144 ? 32.786 76.500 89.669 1.00 45.08 ? 180 LEU B O 1 ATOM 7082 C CB . LEU B 1 144 ? 31.934 77.974 92.444 1.00 47.36 ? 180 LEU B CB 1 ATOM 7083 C CG . LEU B 1 144 ? 31.855 77.931 93.973 1.00 50.58 ? 180 LEU B CG 1 ATOM 7084 C CD1 . LEU B 1 144 ? 32.318 79.250 94.560 1.00 51.09 ? 180 LEU B CD1 1 ATOM 7085 C CD2 . LEU B 1 144 ? 30.444 77.608 94.423 1.00 53.29 ? 180 LEU B CD2 1 ATOM 7086 N N . PRO B 1 145 ? 30.795 77.524 89.510 1.00 49.70 ? 181 PRO B N 1 ATOM 7087 C CA . PRO B 1 145 ? 30.999 77.804 88.090 1.00 43.19 ? 181 PRO B CA 1 ATOM 7088 C C . PRO B 1 145 ? 32.275 78.618 87.878 1.00 45.55 ? 181 PRO B C 1 ATOM 7089 O O . PRO B 1 145 ? 32.692 79.374 88.757 1.00 40.36 ? 181 PRO B O 1 ATOM 7090 C CB . PRO B 1 145 ? 29.773 78.644 87.728 1.00 50.16 ? 181 PRO B CB 1 ATOM 7091 C CG . PRO B 1 145 ? 28.725 78.229 88.733 1.00 47.72 ? 181 PRO B CG 1 ATOM 7092 C CD . PRO B 1 145 ? 29.496 78.016 89.998 1.00 46.96 ? 181 PRO B CD 1 ATOM 7093 N N . SER B 1 146 ? 32.894 78.462 86.714 1.00 40.54 ? 182 SER B N 1 ATOM 7094 C CA . SER B 1 146 ? 34.113 79.193 86.412 1.00 38.95 ? 182 SER B CA 1 ATOM 7095 C C . SER B 1 146 ? 33.797 80.563 85.818 1.00 39.25 ? 182 SER B C 1 ATOM 7096 O O . SER B 1 146 ? 32.700 80.793 85.317 1.00 41.13 ? 182 SER B O 1 ATOM 7097 C CB . SER B 1 146 ? 34.991 78.380 85.458 1.00 37.79 ? 182 SER B CB 1 ATOM 7098 O OG . SER B 1 146 ? 34.281 78.073 84.272 1.00 46.08 ? 182 SER B OG 1 ATOM 7099 N N . TYR B 1 147 ? 34.761 81.472 85.903 1.00 37.58 ? 183 TYR B N 1 ATOM 7100 C CA . TYR B 1 147 ? 34.658 82.782 85.282 1.00 39.45 ? 183 TYR B CA 1 ATOM 7101 C C . TYR B 1 147 ? 35.538 82.820 84.043 1.00 38.65 ? 183 TYR B C 1 ATOM 7102 O O . TYR B 1 147 ? 36.720 82.500 84.114 1.00 36.76 ? 183 TYR B O 1 ATOM 7103 C CB . TYR B 1 147 ? 35.130 83.866 86.250 1.00 39.67 ? 183 TYR B CB 1 ATOM 7104 C CG . TYR B 1 147 ? 34.360 83.901 87.545 1.00 46.03 ? 183 TYR B CG 1 ATOM 7105 C CD1 . TYR B 1 147 ? 34.812 83.208 88.660 1.00 41.23 ? 183 TYR B CD1 1 ATOM 7106 C CD2 . TYR B 1 147 ? 33.178 84.630 87.656 1.00 51.45 ? 183 TYR B CD2 1 ATOM 7107 C CE1 . TYR B 1 147 ? 34.110 83.230 89.847 1.00 41.62 ? 183 TYR B CE1 1 ATOM 7108 C CE2 . TYR B 1 147 ? 32.466 84.659 88.846 1.00 53.93 ? 183 TYR B CE2 1 ATOM 7109 C CZ . TYR B 1 147 ? 32.940 83.958 89.937 1.00 51.36 ? 183 TYR B CZ 1 ATOM 7110 O OH . TYR B 1 147 ? 32.244 83.978 91.125 1.00 56.82 ? 183 TYR B OH 1 ATOM 7111 N N . ARG B 1 148 ? 34.969 83.215 82.910 1.00 37.90 ? 184 ARG B N 1 ATOM 7112 C CA . ARG B 1 148 ? 35.736 83.326 81.673 1.00 32.62 ? 184 ARG B CA 1 ATOM 7113 C C . ARG B 1 148 ? 36.508 84.646 81.621 1.00 37.46 ? 184 ARG B C 1 ATOM 7114 O O . ARG B 1 148 ? 35.915 85.725 81.640 1.00 40.06 ? 184 ARG B O 1 ATOM 7115 C CB . ARG B 1 148 ? 34.814 83.199 80.462 1.00 34.69 ? 184 ARG B CB 1 ATOM 7116 C CG . ARG B 1 148 ? 35.520 83.282 79.109 1.00 34.56 ? 184 ARG B CG 1 ATOM 7117 C CD . ARG B 1 148 ? 34.608 82.762 78.017 1.00 36.59 ? 184 ARG B CD 1 ATOM 7118 N NE . ARG B 1 148 ? 35.270 82.682 76.719 1.00 39.17 ? 184 ARG B NE 1 ATOM 7119 C CZ . ARG B 1 148 ? 34.705 82.156 75.639 1.00 36.76 ? 184 ARG B CZ 1 ATOM 7120 N NH1 . ARG B 1 148 ? 33.478 81.657 75.714 1.00 39.28 ? 184 ARG B NH1 1 ATOM 7121 N NH2 . ARG B 1 148 ? 35.368 82.111 74.493 1.00 38.50 ? 184 ARG B NH2 1 ATOM 7122 N N . ILE B 1 149 ? 37.833 84.540 81.557 1.00 33.47 ? 185 ILE B N 1 ATOM 7123 C CA . ILE B 1 149 ? 38.735 85.681 81.561 1.00 31.94 ? 185 ILE B CA 1 ATOM 7124 C C . ILE B 1 149 ? 39.002 86.239 80.164 1.00 35.18 ? 185 ILE B C 1 ATOM 7125 O O . ILE B 1 149 ? 39.100 87.453 79.988 1.00 37.19 ? 185 ILE B O 1 ATOM 7126 C CB . ILE B 1 149 ? 40.092 85.290 82.172 1.00 36.18 ? 185 ILE B CB 1 ATOM 7127 C CG1 . ILE B 1 149 ? 39.896 84.667 83.562 1.00 34.54 ? 185 ILE B CG1 1 ATOM 7128 C CG2 . ILE B 1 149 ? 41.041 86.487 82.193 1.00 32.99 ? 185 ILE B CG2 1 ATOM 7129 C CD1 . ILE B 1 149 ? 39.169 85.561 84.547 1.00 38.86 ? 185 ILE B CD1 1 ATOM 7130 N N . THR B 1 150 ? 39.143 85.359 79.171 1.00 32.85 ? 186 THR B N 1 ATOM 7131 C CA . THR B 1 150 ? 39.371 85.813 77.800 1.00 34.24 ? 186 THR B CA 1 ATOM 7132 C C . THR B 1 150 ? 38.314 85.261 76.847 1.00 35.09 ? 186 THR B C 1 ATOM 7133 O O . THR B 1 150 ? 37.758 84.175 77.080 1.00 32.78 ? 186 THR B O 1 ATOM 7134 C CB . THR B 1 150 ? 40.786 85.449 77.296 1.00 35.02 ? 186 THR B CB 1 ATOM 7135 O OG1 . THR B 1 150 ? 40.884 84.029 77.118 1.00 30.84 ? 186 THR B OG1 1 ATOM 7136 C CG2 . THR B 1 150 ? 41.845 85.928 78.292 1.00 31.28 ? 186 THR B CG2 1 ATOM 7137 N N . TRP B 1 151 ? 38.033 86.016 75.784 1.00 34.26 ? 187 TRP B N 1 ATOM 7138 C CA . TRP B 1 151 ? 37.016 85.635 74.805 1.00 34.58 ? 187 TRP B CA 1 ATOM 7139 C C . TRP B 1 151 ? 37.567 85.606 73.388 1.00 35.62 ? 187 TRP B C 1 ATOM 7140 O O . TRP B 1 151 ? 36.830 85.341 72.440 1.00 37.64 ? 187 TRP B O 1 ATOM 7141 C CB . TRP B 1 151 ? 35.823 86.596 74.855 1.00 39.18 ? 187 TRP B CB 1 ATOM 7142 C CG . TRP B 1 151 ? 35.208 86.739 76.228 1.00 41.36 ? 187 TRP B CG 1 ATOM 7143 C CD1 . TRP B 1 151 ? 35.720 87.430 77.283 1.00 36.91 ? 187 TRP B CD1 1 ATOM 7144 C CD2 . TRP B 1 151 ? 33.960 86.186 76.676 1.00 39.65 ? 187 TRP B CD2 1 ATOM 7145 N NE1 . TRP B 1 151 ? 34.878 87.331 78.366 1.00 46.28 ? 187 TRP B NE1 1 ATOM 7146 C CE2 . TRP B 1 151 ? 33.789 86.574 78.018 1.00 43.37 ? 187 TRP B CE2 1 ATOM 7147 C CE3 . TRP B 1 151 ? 32.977 85.394 76.072 1.00 46.94 ? 187 TRP B CE3 1 ATOM 7148 C CZ2 . TRP B 1 151 ? 32.673 86.203 78.770 1.00 45.52 ? 187 TRP B CZ2 1 ATOM 7149 C CZ3 . TRP B 1 151 ? 31.863 85.023 76.823 1.00 44.72 ? 187 TRP B CZ3 1 ATOM 7150 C CH2 . TRP B 1 151 ? 31.725 85.427 78.157 1.00 47.16 ? 187 TRP B CH2 1 ATOM 7151 N N . THR B 1 152 ? 38.866 85.858 73.249 1.00 36.35 ? 188 THR B N 1 ATOM 7152 C CA . THR B 1 152 ? 39.504 86.011 71.941 1.00 30.62 ? 188 THR B CA 1 ATOM 7153 C C . THR B 1 152 ? 40.110 84.738 71.344 1.00 32.77 ? 188 THR B C 1 ATOM 7154 O O . THR B 1 152 ? 40.556 84.736 70.199 1.00 30.91 ? 188 THR B O 1 ATOM 7155 C CB . THR B 1 152 ? 40.625 87.055 72.022 1.00 35.53 ? 188 THR B CB 1 ATOM 7156 O OG1 . THR B 1 152 ? 41.452 86.765 73.157 1.00 35.36 ? 188 THR B OG1 1 ATOM 7157 C CG2 . THR B 1 152 ? 40.037 88.466 72.193 1.00 36.34 ? 188 THR B CG2 1 ATOM 7158 N N . GLY B 1 153 ? 40.141 83.659 72.109 1.00 32.25 ? 189 GLY B N 1 ATOM 7159 C CA . GLY B 1 153 ? 40.833 82.461 71.665 1.00 30.15 ? 189 GLY B CA 1 ATOM 7160 C C . GLY B 1 153 ? 40.255 81.789 70.435 1.00 32.82 ? 189 GLY B C 1 ATOM 7161 O O . GLY B 1 153 ? 39.048 81.557 70.351 1.00 31.59 ? 189 GLY B O 1 ATOM 7162 N N . LYS B 1 154 ? 41.132 81.460 69.488 1.00 33.74 ? 190 LYS B N 1 ATOM 7163 C CA . LYS B 1 154 ? 40.738 80.817 68.236 1.00 32.38 ? 190 LYS B CA 1 ATOM 7164 C C . LYS B 1 154 ? 41.822 79.823 67.846 1.00 31.45 ? 190 LYS B C 1 ATOM 7165 O O . LYS B 1 154 ? 43.004 80.167 67.835 1.00 29.74 ? 190 LYS B O 1 ATOM 7166 C CB . LYS B 1 154 ? 40.558 81.873 67.139 1.00 32.61 ? 190 LYS B CB 1 ATOM 7167 C CG . LYS B 1 154 ? 39.788 81.404 65.935 1.00 43.38 ? 190 LYS B CG 1 ATOM 7168 C CD . LYS B 1 154 ? 39.668 82.519 64.887 1.00 50.78 ? 190 LYS B CD 1 ATOM 7169 N N . GLU B 1 155 ? 41.426 78.591 67.531 1.00 35.26 ? 191 GLU B N 1 ATOM 7170 C CA . GLU B 1 155 ? 42.392 77.539 67.217 1.00 37.91 ? 191 GLU B CA 1 ATOM 7171 C C . GLU B 1 155 ? 43.418 78.004 66.188 1.00 36.06 ? 191 GLU B C 1 ATOM 7172 O O . GLU B 1 155 ? 43.063 78.601 65.186 1.00 33.86 ? 191 GLU B O 1 ATOM 7173 C CB . GLU B 1 155 ? 41.690 76.262 66.725 1.00 41.11 ? 191 GLU B CB 1 ATOM 7174 C CG . GLU B 1 155 ? 42.659 75.143 66.324 1.00 45.82 ? 191 GLU B CG 1 ATOM 7175 C CD . GLU B 1 155 ? 41.973 73.804 66.027 1.00 56.13 ? 191 GLU B CD 1 ATOM 7176 O OE1 . GLU B 1 155 ? 42.309 72.799 66.706 1.00 50.26 ? 191 GLU B OE1 1 ATOM 7177 O OE2 . GLU B 1 155 ? 41.121 73.751 65.105 1.00 59.69 ? 191 GLU B OE2 1 ATOM 7178 N N . ASP B 1 156 ? 44.692 77.742 66.457 1.00 34.30 ? 192 ASP B N 1 ATOM 7179 C CA . ASP B 1 156 ? 45.771 78.031 65.508 1.00 33.77 ? 192 ASP B CA 1 ATOM 7180 C C . ASP B 1 156 ? 46.002 79.514 65.263 1.00 34.19 ? 192 ASP B C 1 ATOM 7181 O O . ASP B 1 156 ? 46.860 79.874 64.465 1.00 36.52 ? 192 ASP B O 1 ATOM 7182 C CB . ASP B 1 156 ? 45.536 77.332 64.159 1.00 38.35 ? 192 ASP B CB 1 ATOM 7183 C CG . ASP B 1 156 ? 45.878 75.856 64.193 1.00 39.76 ? 192 ASP B CG 1 ATOM 7184 O OD1 . ASP B 1 156 ? 46.601 75.435 65.121 1.00 42.57 ? 192 ASP B OD1 1 ATOM 7185 O OD2 . ASP B 1 156 ? 45.439 75.114 63.279 1.00 49.98 ? 192 ASP B OD2 1 ATOM 7186 N N . ILE B 1 157 ? 45.258 80.378 65.947 1.00 30.26 ? 193 ILE B N 1 ATOM 7187 C CA . ILE B 1 157 ? 45.384 81.811 65.695 1.00 33.49 ? 193 ILE B CA 1 ATOM 7188 C C . ILE B 1 157 ? 45.692 82.642 66.939 1.00 32.38 ? 193 ILE B C 1 ATOM 7189 O O . ILE B 1 157 ? 46.748 83.264 67.023 1.00 35.05 ? 193 ILE B O 1 ATOM 7190 C CB . ILE B 1 157 ? 44.133 82.375 64.995 1.00 32.80 ? 193 ILE B CB 1 ATOM 7191 C CG1 . ILE B 1 157 ? 43.924 81.660 63.658 1.00 37.69 ? 193 ILE B CG1 1 ATOM 7192 C CG2 . ILE B 1 157 ? 44.284 83.877 64.775 1.00 31.67 ? 193 ILE B CG2 1 ATOM 7193 C CD1 . ILE B 1 157 ? 42.686 82.140 62.893 1.00 40.93 ? 193 ILE B CD1 1 ATOM 7194 N N . ILE B 1 158 ? 44.770 82.668 67.894 1.00 28.18 ? 194 ILE B N 1 ATOM 7195 C CA . ILE B 1 158 ? 44.989 83.410 69.125 1.00 28.49 ? 194 ILE B CA 1 ATOM 7196 C C . ILE B 1 158 ? 45.101 82.439 70.300 1.00 27.16 ? 194 ILE B C 1 ATOM 7197 O O . ILE B 1 158 ? 44.195 81.644 70.543 1.00 29.33 ? 194 ILE B O 1 ATOM 7198 C CB . ILE B 1 158 ? 43.816 84.366 69.414 1.00 29.99 ? 194 ILE B CB 1 ATOM 7199 C CG1 . ILE B 1 158 ? 43.586 85.339 68.236 1.00 32.02 ? 194 ILE B CG1 1 ATOM 7200 C CG2 . ILE B 1 158 ? 44.048 85.095 70.703 1.00 27.98 ? 194 ILE B CG2 1 ATOM 7201 C CD1 . ILE B 1 158 ? 44.741 86.289 67.984 1.00 32.54 ? 194 ILE B CD1 1 ATOM 7202 N N . TYR B 1 159 ? 46.200 82.518 71.038 1.00 25.90 ? 195 TYR B N 1 ATOM 7203 C CA . TYR B 1 159 ? 46.401 81.652 72.199 1.00 25.86 ? 195 TYR B CA 1 ATOM 7204 C C . TYR B 1 159 ? 46.422 82.501 73.459 1.00 26.16 ? 195 TYR B C 1 ATOM 7205 O O . TYR B 1 159 ? 47.303 83.334 73.607 1.00 28.22 ? 195 TYR B O 1 ATOM 7206 C CB . TYR B 1 159 ? 47.754 80.955 72.101 1.00 24.36 ? 195 TYR B CB 1 ATOM 7207 C CG . TYR B 1 159 ? 47.977 80.155 70.843 1.00 28.18 ? 195 TYR B CG 1 ATOM 7208 C CD1 . TYR B 1 159 ? 48.217 80.787 69.627 1.00 27.56 ? 195 TYR B CD1 1 ATOM 7209 C CD2 . TYR B 1 159 ? 47.986 78.769 70.874 1.00 27.74 ? 195 TYR B CD2 1 ATOM 7210 C CE1 . TYR B 1 159 ? 48.448 80.055 68.474 1.00 31.54 ? 195 TYR B CE1 1 ATOM 7211 C CE2 . TYR B 1 159 ? 48.207 78.021 69.713 1.00 32.99 ? 195 TYR B CE2 1 ATOM 7212 C CZ . TYR B 1 159 ? 48.441 78.674 68.518 1.00 31.79 ? 195 TYR B CZ 1 ATOM 7213 O OH . TYR B 1 159 ? 48.674 77.952 67.359 1.00 35.14 ? 195 TYR B OH 1 ATOM 7214 N N . ASN B 1 160 ? 45.472 82.303 74.369 1.00 27.18 ? 196 ASN B N 1 ATOM 7215 C CA . ASN B 1 160 ? 45.534 82.978 75.664 1.00 26.81 ? 196 ASN B CA 1 ATOM 7216 C C . ASN B 1 160 ? 45.936 81.984 76.736 1.00 25.69 ? 196 ASN B C 1 ATOM 7217 O O . ASN B 1 160 ? 45.235 81.002 76.935 1.00 26.33 ? 196 ASN B O 1 ATOM 7218 C CB . ASN B 1 160 ? 44.170 83.559 76.054 1.00 27.90 ? 196 ASN B CB 1 ATOM 7219 C CG . ASN B 1 160 ? 43.686 84.610 75.087 1.00 32.76 ? 196 ASN B CG 1 ATOM 7220 O OD1 . ASN B 1 160 ? 44.217 85.723 75.041 1.00 32.06 ? 196 ASN B OD1 1 ATOM 7221 N ND2 . ASN B 1 160 ? 42.661 84.269 74.316 1.00 31.70 ? 196 ASN B ND2 1 ATOM 7222 N N . GLY B 1 161 ? 47.047 82.229 77.424 1.00 25.38 ? 197 GLY B N 1 ATOM 7223 C CA . GLY B 1 161 ? 47.402 81.411 78.579 1.00 28.29 ? 197 GLY B CA 1 ATOM 7224 C C . GLY B 1 161 ? 48.142 80.133 78.222 1.00 29.33 ? 197 GLY B C 1 ATOM 7225 O O . GLY B 1 161 ? 48.557 79.364 79.093 1.00 28.70 ? 197 GLY B O 1 ATOM 7226 N N . ILE B 1 162 ? 48.297 79.896 76.929 1.00 24.69 ? 198 ILE B N 1 ATOM 7227 C CA . ILE B 1 162 ? 49.114 78.789 76.453 1.00 26.27 ? 198 ILE B CA 1 ATOM 7228 C C . ILE B 1 162 ? 49.983 79.299 75.310 1.00 28.76 ? 198 ILE B C 1 ATOM 7229 O O . ILE B 1 162 ? 49.647 80.289 74.655 1.00 29.24 ? 198 ILE B O 1 ATOM 7230 C CB . ILE B 1 162 ? 48.250 77.613 75.952 1.00 26.55 ? 198 ILE B CB 1 ATOM 7231 C CG1 . ILE B 1 162 ? 47.196 78.114 74.959 1.00 25.65 ? 198 ILE B CG1 1 ATOM 7232 C CG2 . ILE B 1 162 ? 47.580 76.859 77.124 1.00 23.23 ? 198 ILE B CG2 1 ATOM 7233 C CD1 . ILE B 1 162 ? 46.310 77.010 74.402 1.00 28.91 ? 198 ILE B CD1 1 ATOM 7234 N N . THR B 1 163 ? 51.095 78.612 75.059 1.00 26.00 ? 199 THR B N 1 ATOM 7235 C CA . THR B 1 163 ? 52.031 79.022 74.025 1.00 27.74 ? 199 THR B CA 1 ATOM 7236 C C . THR B 1 163 ? 51.668 78.411 72.680 1.00 30.43 ? 199 THR B C 1 ATOM 7237 O O . THR B 1 163 ? 50.969 77.397 72.614 1.00 29.37 ? 199 THR B O 1 ATOM 7238 C CB . THR B 1 163 ? 53.455 78.586 74.375 1.00 31.29 ? 199 THR B CB 1 ATOM 7239 O OG1 . THR B 1 163 ? 53.452 77.190 74.681 1.00 28.52 ? 199 THR B OG1 1 ATOM 7240 C CG2 . THR B 1 163 ? 53.990 79.367 75.588 1.00 26.18 ? 199 THR B CG2 1 ATOM 7241 N N . ASP B 1 164 ? 52.145 79.041 71.612 1.00 29.17 ? 200 ASP B N 1 ATOM 7242 C CA . ASP B 1 164 ? 52.073 78.457 70.279 1.00 30.01 ? 200 ASP B CA 1 ATOM 7243 C C . ASP B 1 164 ? 53.290 77.555 70.076 1.00 29.14 ? 200 ASP B C 1 ATOM 7244 O O . ASP B 1 164 ? 54.060 77.341 71.005 1.00 26.11 ? 200 ASP B O 1 ATOM 7245 C CB . ASP B 1 164 ? 51.998 79.550 69.203 1.00 29.39 ? 200 ASP B CB 1 ATOM 7246 C CG . ASP B 1 164 ? 53.323 80.254 68.991 1.00 31.78 ? 200 ASP B CG 1 ATOM 7247 O OD1 . ASP B 1 164 ? 54.212 80.125 69.858 1.00 26.34 ? 200 ASP B OD1 1 ATOM 7248 O OD2 . ASP B 1 164 ? 53.474 80.941 67.959 1.00 33.35 ? 200 ASP B OD2 1 ATOM 7249 N N . TRP B 1 165 ? 53.472 77.025 68.869 1.00 26.85 ? 201 TRP B N 1 ATOM 7250 C CA . TRP B 1 165 ? 54.516 76.022 68.657 1.00 27.07 ? 201 TRP B CA 1 ATOM 7251 C C . TRP B 1 165 ? 55.926 76.461 69.050 1.00 26.42 ? 201 TRP B C 1 ATOM 7252 O O . TRP B 1 165 ? 56.631 75.757 69.798 1.00 24.81 ? 201 TRP B O 1 ATOM 7253 C CB . TRP B 1 165 ? 54.515 75.499 67.216 1.00 22.92 ? 201 TRP B CB 1 ATOM 7254 C CG . TRP B 1 165 ? 55.371 74.291 67.085 1.00 22.52 ? 201 TRP B CG 1 ATOM 7255 C CD1 . TRP B 1 165 ? 54.961 72.985 67.100 1.00 22.96 ? 201 TRP B CD1 1 ATOM 7256 C CD2 . TRP B 1 165 ? 56.795 74.264 66.959 1.00 22.00 ? 201 TRP B CD2 1 ATOM 7257 N NE1 . TRP B 1 165 ? 56.046 72.150 66.990 1.00 21.93 ? 201 TRP B NE1 1 ATOM 7258 C CE2 . TRP B 1 165 ? 57.183 72.911 66.894 1.00 23.34 ? 201 TRP B CE2 1 ATOM 7259 C CE3 . TRP B 1 165 ? 57.783 75.254 66.890 1.00 21.91 ? 201 TRP B CE3 1 ATOM 7260 C CZ2 . TRP B 1 165 ? 58.516 72.522 66.772 1.00 25.34 ? 201 TRP B CZ2 1 ATOM 7261 C CZ3 . TRP B 1 165 ? 59.109 74.866 66.762 1.00 23.23 ? 201 TRP B CZ3 1 ATOM 7262 C CH2 . TRP B 1 165 ? 59.464 73.510 66.709 1.00 23.34 ? 201 TRP B CH2 1 ATOM 7263 N N . VAL B 1 166 ? 56.349 77.613 68.549 1.00 23.14 ? 202 VAL B N 1 ATOM 7264 C CA . VAL B 1 166 ? 57.737 78.042 68.718 1.00 22.31 ? 202 VAL B CA 1 ATOM 7265 C C . VAL B 1 166 ? 58.022 78.601 70.128 1.00 24.32 ? 202 VAL B C 1 ATOM 7266 O O . VAL B 1 166 ? 59.129 78.447 70.657 1.00 24.75 ? 202 VAL B O 1 ATOM 7267 C CB . VAL B 1 166 ? 58.154 79.025 67.567 1.00 24.42 ? 202 VAL B CB 1 ATOM 7268 C CG1 . VAL B 1 166 ? 57.504 80.384 67.758 1.00 23.75 ? 202 VAL B CG1 1 ATOM 7269 C CG2 . VAL B 1 166 ? 59.655 79.142 67.473 1.00 23.65 ? 202 VAL B CG2 1 ATOM 7270 N N . TYR B 1 167 ? 57.027 79.223 70.761 1.00 24.53 ? 203 TYR B N 1 ATOM 7271 C CA . TYR B 1 167 ? 57.200 79.622 72.163 1.00 24.57 ? 203 TYR B CA 1 ATOM 7272 C C . TYR B 1 167 ? 57.260 78.388 73.080 1.00 24.24 ? 203 TYR B C 1 ATOM 7273 O O . TYR B 1 167 ? 58.069 78.332 74.001 1.00 25.44 ? 203 TYR B O 1 ATOM 7274 C CB . TYR B 1 167 ? 56.081 80.556 72.622 1.00 25.36 ? 203 TYR B CB 1 ATOM 7275 C CG . TYR B 1 167 ? 56.385 82.030 72.454 1.00 27.98 ? 203 TYR B CG 1 ATOM 7276 C CD1 . TYR B 1 167 ? 56.982 82.743 73.474 1.00 27.44 ? 203 TYR B CD1 1 ATOM 7277 C CD2 . TYR B 1 167 ? 56.065 82.705 71.280 1.00 28.01 ? 203 TYR B CD2 1 ATOM 7278 C CE1 . TYR B 1 167 ? 57.260 84.087 73.347 1.00 31.14 ? 203 TYR B CE1 1 ATOM 7279 C CE2 . TYR B 1 167 ? 56.342 84.066 71.133 1.00 29.74 ? 203 TYR B CE2 1 ATOM 7280 C CZ . TYR B 1 167 ? 56.939 84.750 72.179 1.00 31.79 ? 203 TYR B CZ 1 ATOM 7281 O OH . TYR B 1 167 ? 57.216 86.095 72.084 1.00 28.82 ? 203 TYR B OH 1 ATOM 7282 N N . GLU B 1 168 ? 56.422 77.390 72.822 1.00 26.32 ? 204 GLU B N 1 ATOM 7283 C CA . GLU B 1 168 ? 56.468 76.178 73.637 1.00 24.16 ? 204 GLU B CA 1 ATOM 7284 C C . GLU B 1 168 ? 57.853 75.532 73.539 1.00 27.75 ? 204 GLU B C 1 ATOM 7285 O O . GLU B 1 168 ? 58.479 75.206 74.556 1.00 29.40 ? 204 GLU B O 1 ATOM 7286 C CB . GLU B 1 168 ? 55.396 75.180 73.184 1.00 25.16 ? 204 GLU B CB 1 ATOM 7287 C CG . GLU B 1 168 ? 55.602 73.788 73.798 1.00 25.43 ? 204 GLU B CG 1 ATOM 7288 C CD . GLU B 1 168 ? 54.627 72.727 73.297 1.00 28.30 ? 204 GLU B CD 1 ATOM 7289 O OE1 . GLU B 1 168 ? 53.617 73.075 72.651 1.00 22.44 ? 204 GLU B OE1 1 ATOM 7290 O OE2 . GLU B 1 168 ? 54.875 71.529 73.570 1.00 29.25 ? 204 GLU B OE2 1 ATOM 7291 N N . GLU B 1 169 ? 58.321 75.347 72.305 1.00 26.33 ? 205 GLU B N 1 ATOM 7292 C CA . GLU B 1 169 ? 59.573 74.634 72.014 1.00 26.33 ? 205 GLU B CA 1 ATOM 7293 C C . GLU B 1 169 ? 60.843 75.413 72.357 1.00 25.95 ? 205 GLU B C 1 ATOM 7294 O O . GLU B 1 169 ? 61.761 74.852 72.956 1.00 25.96 ? 205 GLU B O 1 ATOM 7295 C CB . GLU B 1 169 ? 59.627 74.206 70.535 1.00 23.50 ? 205 GLU B CB 1 ATOM 7296 C CG . GLU B 1 169 ? 60.966 73.621 70.089 1.00 22.07 ? 205 GLU B CG 1 ATOM 7297 C CD . GLU B 1 169 ? 61.231 72.228 70.648 1.00 28.49 ? 205 GLU B CD 1 ATOM 7298 O OE1 . GLU B 1 169 ? 60.370 71.685 71.392 1.00 29.38 ? 205 GLU B OE1 1 ATOM 7299 O OE2 . GLU B 1 169 ? 62.307 71.672 70.335 1.00 28.90 ? 205 GLU B OE2 1 ATOM 7300 N N . GLU B 1 170 ? 60.891 76.698 72.002 1.00 21.57 ? 206 GLU B N 1 ATOM 7301 C CA . GLU B 1 170 ? 62.135 77.463 72.074 1.00 24.01 ? 206 GLU B CA 1 ATOM 7302 C C . GLU B 1 170 ? 62.208 78.584 73.137 1.00 25.97 ? 206 GLU B C 1 ATOM 7303 O O . GLU B 1 170 ? 63.296 79.060 73.456 1.00 26.37 ? 206 GLU B O 1 ATOM 7304 C CB . GLU B 1 170 ? 62.445 78.077 70.696 1.00 25.05 ? 206 GLU B CB 1 ATOM 7305 C CG . GLU B 1 170 ? 62.380 77.080 69.521 1.00 24.84 ? 206 GLU B CG 1 ATOM 7306 C CD . GLU B 1 170 ? 63.530 76.092 69.496 1.00 26.94 ? 206 GLU B CD 1 ATOM 7307 O OE1 . GLU B 1 170 ? 64.340 76.064 70.450 1.00 28.34 ? 206 GLU B OE1 1 ATOM 7308 O OE2 . GLU B 1 170 ? 63.618 75.317 68.511 1.00 28.97 ? 206 GLU B OE2 1 ATOM 7309 N N . VAL B 1 171 ? 61.080 79.044 73.653 1.00 25.31 ? 207 VAL B N 1 ATOM 7310 C CA . VAL B 1 171 ? 61.140 80.175 74.588 1.00 27.80 ? 207 VAL B CA 1 ATOM 7311 C C . VAL B 1 171 ? 60.845 79.789 76.038 1.00 28.77 ? 207 VAL B C 1 ATOM 7312 O O . VAL B 1 171 ? 61.673 80.005 76.941 1.00 33.42 ? 207 VAL B O 1 ATOM 7313 C CB . VAL B 1 171 ? 60.199 81.329 74.168 1.00 25.42 ? 207 VAL B CB 1 ATOM 7314 C CG1 . VAL B 1 171 ? 60.423 82.521 75.072 1.00 29.42 ? 207 VAL B CG1 1 ATOM 7315 C CG2 . VAL B 1 171 ? 60.460 81.719 72.729 1.00 24.18 ? 207 VAL B CG2 1 ATOM 7316 N N . PHE B 1 172 ? 59.666 79.219 76.261 1.00 27.06 ? 208 PHE B N 1 ATOM 7317 C CA . PHE B 1 172 ? 59.211 78.898 77.604 1.00 28.65 ? 208 PHE B CA 1 ATOM 7318 C C . PHE B 1 172 ? 59.436 77.449 78.048 1.00 30.67 ? 208 PHE B C 1 ATOM 7319 O O . PHE B 1 172 ? 59.337 77.160 79.237 1.00 28.35 ? 208 PHE B O 1 ATOM 7320 C CB . PHE B 1 172 ? 57.740 79.310 77.777 1.00 28.16 ? 208 PHE B CB 1 ATOM 7321 C CG . PHE B 1 172 ? 57.559 80.788 77.933 1.00 31.14 ? 208 PHE B CG 1 ATOM 7322 C CD1 . PHE B 1 172 ? 58.100 81.446 79.031 1.00 37.93 ? 208 PHE B CD1 1 ATOM 7323 C CD2 . PHE B 1 172 ? 56.887 81.520 76.990 1.00 31.09 ? 208 PHE B CD2 1 ATOM 7324 C CE1 . PHE B 1 172 ? 57.957 82.812 79.178 1.00 40.64 ? 208 PHE B CE1 1 ATOM 7325 C CE2 . PHE B 1 172 ? 56.741 82.888 77.119 1.00 34.57 ? 208 PHE B CE2 1 ATOM 7326 C CZ . PHE B 1 172 ? 57.278 83.537 78.208 1.00 38.55 ? 208 PHE B CZ 1 ATOM 7327 N N . SER B 1 173 ? 59.736 76.550 77.106 1.00 28.15 ? 209 SER B N 1 ATOM 7328 C CA . SER B 1 173 ? 59.884 75.117 77.405 1.00 26.50 ? 209 SER B CA 1 ATOM 7329 C C . SER B 1 173 ? 58.686 74.603 78.188 1.00 28.16 ? 209 SER B C 1 ATOM 7330 O O . SER B 1 173 ? 58.832 73.831 79.156 1.00 25.97 ? 209 SER B O 1 ATOM 7331 C CB . SER B 1 173 ? 61.161 74.846 78.199 1.00 28.29 ? 209 SER B CB 1 ATOM 7332 O OG . SER B 1 173 ? 62.309 75.273 77.488 1.00 31.82 ? 209 SER B OG 1 ATOM 7333 N N . ALA B 1 174 ? 57.502 75.037 77.772 1.00 23.18 ? 210 ALA B N 1 ATOM 7334 C CA . ALA B 1 174 ? 56.278 74.688 78.469 1.00 26.83 ? 210 ALA B CA 1 ATOM 7335 C C . ALA B 1 174 ? 55.105 75.109 77.622 1.00 27.34 ? 210 ALA B C 1 ATOM 7336 O O . ALA B 1 174 ? 55.211 76.050 76.843 1.00 26.52 ? 210 ALA B O 1 ATOM 7337 C CB . ALA B 1 174 ? 56.232 75.401 79.848 1.00 27.76 ? 210 ALA B CB 1 ATOM 7338 N N . TYR B 1 175 ? 53.989 74.409 77.768 1.00 23.24 ? 211 TYR B N 1 ATOM 7339 C CA . TYR B 1 175 ? 52.758 74.794 77.106 1.00 25.57 ? 211 TYR B CA 1 ATOM 7340 C C . TYR B 1 175 ? 52.152 75.989 77.842 1.00 27.78 ? 211 TYR B C 1 ATOM 7341 O O . TYR B 1 175 ? 51.508 76.847 77.238 1.00 27.76 ? 211 TYR B O 1 ATOM 7342 C CB . TYR B 1 175 ? 51.772 73.641 77.168 1.00 24.95 ? 211 TYR B CB 1 ATOM 7343 C CG . TYR B 1 175 ? 50.601 73.721 76.200 1.00 27.87 ? 211 TYR B CG 1 ATOM 7344 C CD1 . TYR B 1 175 ? 50.611 74.584 75.102 1.00 26.42 ? 211 TYR B CD1 1 ATOM 7345 C CD2 . TYR B 1 175 ? 49.484 72.917 76.391 1.00 27.67 ? 211 TYR B CD2 1 ATOM 7346 C CE1 . TYR B 1 175 ? 49.537 74.620 74.219 1.00 25.61 ? 211 TYR B CE1 1 ATOM 7347 C CE2 . TYR B 1 175 ? 48.408 72.959 75.529 1.00 24.73 ? 211 TYR B CE2 1 ATOM 7348 C CZ . TYR B 1 175 ? 48.436 73.809 74.449 1.00 29.27 ? 211 TYR B CZ 1 ATOM 7349 O OH . TYR B 1 175 ? 47.352 73.810 73.600 1.00 30.04 ? 211 TYR B OH 1 ATOM 7350 N N . SER B 1 176 ? 52.351 76.030 79.154 1.00 25.47 ? 212 SER B N 1 ATOM 7351 C CA . SER B 1 176 ? 51.748 77.065 79.994 1.00 29.08 ? 212 SER B CA 1 ATOM 7352 C C . SER B 1 176 ? 52.269 78.468 79.724 1.00 25.72 ? 212 SER B C 1 ATOM 7353 O O . SER B 1 176 ? 53.464 78.677 79.583 1.00 26.29 ? 212 SER B O 1 ATOM 7354 C CB . SER B 1 176 ? 51.977 76.762 81.471 1.00 31.49 ? 212 SER B CB 1 ATOM 7355 O OG . SER B 1 176 ? 51.408 77.802 82.248 1.00 38.51 ? 212 SER B OG 1 ATOM 7356 N N . ALA B 1 177 ? 51.356 79.428 79.678 1.00 27.32 ? 213 ALA B N 1 ATOM 7357 C CA . ALA B 1 177 ? 51.725 80.839 79.661 1.00 33.08 ? 213 ALA B CA 1 ATOM 7358 C C . ALA B 1 177 ? 50.842 81.582 80.666 1.00 32.70 ? 213 ALA B C 1 ATOM 7359 O O . ALA B 1 177 ? 50.244 82.613 80.333 1.00 30.02 ? 213 ALA B O 1 ATOM 7360 C CB . ALA B 1 177 ? 51.566 81.422 78.278 1.00 24.95 ? 213 ALA B CB 1 ATOM 7361 N N . LEU B 1 178 ? 50.774 81.019 81.875 1.00 31.25 ? 214 LEU B N 1 ATOM 7362 C CA . LEU B 1 178 ? 49.947 81.478 83.003 1.00 32.38 ? 214 LEU B CA 1 ATOM 7363 C C . LEU B 1 178 ? 50.856 81.597 84.218 1.00 32.16 ? 214 LEU B C 1 ATOM 7364 O O . LEU B 1 178 ? 51.644 80.691 84.480 1.00 30.72 ? 214 LEU B O 1 ATOM 7365 C CB . LEU B 1 178 ? 48.892 80.408 83.316 1.00 30.95 ? 214 LEU B CB 1 ATOM 7366 C CG . LEU B 1 178 ? 47.392 80.607 83.097 1.00 37.37 ? 214 LEU B CG 1 ATOM 7367 C CD1 . LEU B 1 178 ? 47.088 81.455 81.884 1.00 33.68 ? 214 LEU B CD1 1 ATOM 7368 C CD2 . LEU B 1 178 ? 46.674 79.266 82.996 1.00 33.44 ? 214 LEU B CD2 1 ATOM 7369 N N . TRP B 1 179 ? 50.765 82.691 84.972 1.00 28.35 ? 215 TRP B N 1 ATOM 7370 C CA . TRP B 1 179 ? 51.629 82.860 86.146 1.00 30.46 ? 215 TRP B CA 1 ATOM 7371 C C . TRP B 1 179 ? 50.862 83.493 87.317 1.00 32.28 ? 215 TRP B C 1 ATOM 7372 O O . TRP B 1 179 ? 50.652 84.696 87.307 1.00 29.87 ? 215 TRP B O 1 ATOM 7373 C CB . TRP B 1 179 ? 52.836 83.746 85.813 1.00 25.93 ? 215 TRP B CB 1 ATOM 7374 C CG . TRP B 1 179 ? 53.756 83.214 84.735 1.00 32.59 ? 215 TRP B CG 1 ATOM 7375 C CD1 . TRP B 1 179 ? 54.852 82.408 84.914 1.00 31.45 ? 215 TRP B CD1 1 ATOM 7376 C CD2 . TRP B 1 179 ? 53.680 83.479 83.322 1.00 30.93 ? 215 TRP B CD2 1 ATOM 7377 N NE1 . TRP B 1 179 ? 55.451 82.144 83.694 1.00 34.04 ? 215 TRP B NE1 1 ATOM 7378 C CE2 . TRP B 1 179 ? 54.744 82.781 82.704 1.00 33.64 ? 215 TRP B CE2 1 ATOM 7379 C CE3 . TRP B 1 179 ? 52.804 84.215 82.519 1.00 31.68 ? 215 TRP B CE3 1 ATOM 7380 C CZ2 . TRP B 1 179 ? 54.961 82.814 81.319 1.00 30.72 ? 215 TRP B CZ2 1 ATOM 7381 C CZ3 . TRP B 1 179 ? 53.022 84.247 81.144 1.00 32.64 ? 215 TRP B CZ3 1 ATOM 7382 C CH2 . TRP B 1 179 ? 54.089 83.552 80.560 1.00 32.13 ? 215 TRP B CH2 1 ATOM 7383 N N . TRP B 1 180 ? 50.437 82.693 88.302 1.00 28.15 ? 216 TRP B N 1 ATOM 7384 C CA . TRP B 1 180 ? 49.738 83.221 89.488 1.00 29.00 ? 216 TRP B CA 1 ATOM 7385 C C . TRP B 1 180 ? 50.713 84.030 90.330 1.00 27.53 ? 216 TRP B C 1 ATOM 7386 O O . TRP B 1 180 ? 51.903 83.727 90.343 1.00 30.90 ? 216 TRP B O 1 ATOM 7387 C CB . TRP B 1 180 ? 49.244 82.084 90.389 1.00 31.54 ? 216 TRP B CB 1 ATOM 7388 C CG . TRP B 1 180 ? 48.060 81.307 89.925 1.00 30.05 ? 216 TRP B CG 1 ATOM 7389 C CD1 . TRP B 1 180 ? 48.072 80.089 89.299 1.00 32.82 ? 216 TRP B CD1 1 ATOM 7390 C CD2 . TRP B 1 180 ? 46.679 81.652 90.102 1.00 31.49 ? 216 TRP B CD2 1 ATOM 7391 N NE1 . TRP B 1 180 ? 46.786 79.669 89.059 1.00 34.54 ? 216 TRP B NE1 1 ATOM 7392 C CE2 . TRP B 1 180 ? 45.913 80.608 89.544 1.00 32.12 ? 216 TRP B CE2 1 ATOM 7393 C CE3 . TRP B 1 180 ? 46.017 82.752 90.659 1.00 33.14 ? 216 TRP B CE3 1 ATOM 7394 C CZ2 . TRP B 1 180 ? 44.519 80.631 89.527 1.00 30.23 ? 216 TRP B CZ2 1 ATOM 7395 C CZ3 . TRP B 1 180 ? 44.633 82.770 90.648 1.00 31.61 ? 216 TRP B CZ3 1 ATOM 7396 C CH2 . TRP B 1 180 ? 43.899 81.717 90.080 1.00 33.43 ? 216 TRP B CH2 1 ATOM 7397 N N . SER B 1 181 ? 50.223 85.036 91.059 1.00 32.89 ? 217 SER B N 1 ATOM 7398 C CA . SER B 1 181 ? 51.074 85.758 92.014 1.00 32.38 ? 217 SER B CA 1 ATOM 7399 C C . SER B 1 181 ? 51.286 84.893 93.267 1.00 34.87 ? 217 SER B C 1 ATOM 7400 O O . SER B 1 181 ? 50.523 83.959 93.500 1.00 35.26 ? 217 SER B O 1 ATOM 7401 C CB . SER B 1 181 ? 50.450 87.102 92.393 1.00 32.60 ? 217 SER B CB 1 ATOM 7402 O OG . SER B 1 181 ? 49.192 86.909 93.015 1.00 34.24 ? 217 SER B OG 1 ATOM 7403 N N . PRO B 1 182 ? 52.329 85.190 94.066 1.00 34.72 ? 218 PRO B N 1 ATOM 7404 C CA . PRO B 1 182 ? 52.666 84.355 95.230 1.00 37.85 ? 218 PRO B CA 1 ATOM 7405 C C . PRO B 1 182 ? 51.442 84.109 96.114 1.00 38.85 ? 218 PRO B C 1 ATOM 7406 O O . PRO B 1 182 ? 51.286 83.023 96.661 1.00 44.06 ? 218 PRO B O 1 ATOM 7407 C CB . PRO B 1 182 ? 53.697 85.202 95.976 1.00 39.67 ? 218 PRO B CB 1 ATOM 7408 C CG . PRO B 1 182 ? 54.316 86.045 94.935 1.00 39.83 ? 218 PRO B CG 1 ATOM 7409 C CD . PRO B 1 182 ? 53.250 86.330 93.918 1.00 36.12 ? 218 PRO B CD 1 ATOM 7410 N N . ASN B 1 183 ? 50.586 85.125 96.201 1.00 40.40 ? 219 ASN B N 1 ATOM 7411 C CA . ASN B 1 183 ? 49.327 85.133 96.950 1.00 48.63 ? 219 ASN B CA 1 ATOM 7412 C C . ASN B 1 183 ? 48.178 84.346 96.345 1.00 43.14 ? 219 ASN B C 1 ATOM 7413 O O . ASN B 1 183 ? 47.327 83.847 97.058 1.00 40.63 ? 219 ASN B O 1 ATOM 7414 C CB . ASN B 1 183 ? 48.822 86.575 97.030 1.00 48.95 ? 219 ASN B CB 1 ATOM 7415 C CG . ASN B 1 183 ? 48.438 86.966 98.410 1.00 55.47 ? 219 ASN B CG 1 ATOM 7416 O OD1 . ASN B 1 183 ? 48.013 86.124 99.201 1.00 65.32 ? 219 ASN B OD1 1 ATOM 7417 N ND2 . ASN B 1 183 ? 48.599 88.247 98.734 1.00 57.55 ? 219 ASN B ND2 1 ATOM 7418 N N . GLY B 1 184 ? 48.108 84.297 95.023 1.00 39.78 ? 220 GLY B N 1 ATOM 7419 C CA . GLY B 1 184 ? 46.927 83.766 94.377 1.00 36.09 ? 220 GLY B CA 1 ATOM 7420 C C . GLY B 1 184 ? 45.964 84.881 94.023 1.00 39.66 ? 220 GLY B C 1 ATOM 7421 O O . GLY B 1 184 ? 44.898 84.642 93.450 1.00 39.18 ? 220 GLY B O 1 ATOM 7422 N N . THR B 1 185 ? 46.335 86.112 94.361 1.00 35.76 ? 221 THR B N 1 ATOM 7423 C CA . THR B 1 185 ? 45.469 87.250 94.079 1.00 37.95 ? 221 THR B CA 1 ATOM 7424 C C . THR B 1 185 ? 45.416 87.550 92.583 1.00 38.60 ? 221 THR B C 1 ATOM 7425 O O . THR B 1 185 ? 44.341 87.642 91.994 1.00 38.63 ? 221 THR B O 1 ATOM 7426 C CB . THR B 1 185 ? 45.921 88.503 94.842 1.00 45.18 ? 221 THR B CB 1 ATOM 7427 O OG1 . THR B 1 185 ? 45.623 88.335 96.227 1.00 53.08 ? 221 THR B OG1 1 ATOM 7428 C CG2 . THR B 1 185 ? 45.181 89.725 94.336 1.00 47.22 ? 221 THR B CG2 1 ATOM 7429 N N . PHE B 1 186 ? 46.584 87.691 91.969 1.00 36.57 ? 222 PHE B N 1 ATOM 7430 C CA . PHE B 1 186 ? 46.655 88.029 90.557 1.00 34.09 ? 222 PHE B CA 1 ATOM 7431 C C . PHE B 1 186 ? 46.941 86.810 89.678 1.00 35.24 ? 222 PHE B C 1 ATOM 7432 O O . PHE B 1 186 ? 47.670 85.902 90.075 1.00 32.82 ? 222 PHE B O 1 ATOM 7433 C CB . PHE B 1 186 ? 47.747 89.077 90.320 1.00 33.63 ? 222 PHE B CB 1 ATOM 7434 C CG . PHE B 1 186 ? 47.484 90.397 90.993 1.00 34.54 ? 222 PHE B CG 1 ATOM 7435 C CD1 . PHE B 1 186 ? 46.505 91.255 90.510 1.00 35.77 ? 222 PHE B CD1 1 ATOM 7436 C CD2 . PHE B 1 186 ? 48.233 90.791 92.085 1.00 37.52 ? 222 PHE B CD2 1 ATOM 7437 C CE1 . PHE B 1 186 ? 46.269 92.471 91.121 1.00 41.06 ? 222 PHE B CE1 1 ATOM 7438 C CE2 . PHE B 1 186 ? 47.997 92.013 92.701 1.00 40.20 ? 222 PHE B CE2 1 ATOM 7439 C CZ . PHE B 1 186 ? 47.018 92.850 92.213 1.00 37.03 ? 222 PHE B CZ 1 ATOM 7440 N N . LEU B 1 187 ? 46.386 86.820 88.469 1.00 34.12 ? 223 LEU B N 1 ATOM 7441 C CA . LEU B 1 187 ? 46.764 85.857 87.436 1.00 30.54 ? 223 LEU B CA 1 ATOM 7442 C C . LEU B 1 187 ? 47.344 86.616 86.256 1.00 32.48 ? 223 LEU B C 1 ATOM 7443 O O . LEU B 1 187 ? 46.633 87.373 85.590 1.00 32.09 ? 223 LEU B O 1 ATOM 7444 C CB . LEU B 1 187 ? 45.557 85.035 86.979 1.00 29.30 ? 223 LEU B CB 1 ATOM 7445 C CG . LEU B 1 187 ? 45.845 83.977 85.901 1.00 27.86 ? 223 LEU B CG 1 ATOM 7446 C CD1 . LEU B 1 187 ? 46.857 82.958 86.419 1.00 31.88 ? 223 LEU B CD1 1 ATOM 7447 C CD2 . LEU B 1 187 ? 44.581 83.267 85.476 1.00 29.37 ? 223 LEU B CD2 1 ATOM 7448 N N . ALA B 1 188 ? 48.636 86.432 86.001 1.00 29.20 ? 224 ALA B N 1 ATOM 7449 C CA . ALA B 1 188 ? 49.252 87.036 84.833 1.00 31.64 ? 224 ALA B CA 1 ATOM 7450 C C . ALA B 1 188 ? 49.207 86.030 83.680 1.00 33.61 ? 224 ALA B C 1 ATOM 7451 O O . ALA B 1 188 ? 49.227 84.823 83.904 1.00 28.95 ? 224 ALA B O 1 ATOM 7452 C CB . ALA B 1 188 ? 50.683 87.458 85.139 1.00 30.45 ? 224 ALA B CB 1 ATOM 7453 N N . TYR B 1 189 ? 49.122 86.514 82.447 1.00 28.97 ? 225 TYR B N 1 ATOM 7454 C CA . TYR B 1 189 ? 49.123 85.601 81.310 1.00 28.46 ? 225 TYR B CA 1 ATOM 7455 C C . TYR B 1 189 ? 49.607 86.278 80.046 1.00 32.84 ? 225 TYR B C 1 ATOM 7456 O O . TYR B 1 189 ? 49.494 87.492 79.914 1.00 30.10 ? 225 TYR B O 1 ATOM 7457 C CB . TYR B 1 189 ? 47.738 84.986 81.092 1.00 28.44 ? 225 TYR B CB 1 ATOM 7458 C CG . TYR B 1 189 ? 46.664 85.953 80.667 1.00 30.82 ? 225 TYR B CG 1 ATOM 7459 C CD1 . TYR B 1 189 ? 46.442 86.227 79.322 1.00 30.45 ? 225 TYR B CD1 1 ATOM 7460 C CD2 . TYR B 1 189 ? 45.860 86.581 81.602 1.00 33.31 ? 225 TYR B CD2 1 ATOM 7461 C CE1 . TYR B 1 189 ? 45.452 87.101 78.929 1.00 32.40 ? 225 TYR B CE1 1 ATOM 7462 C CE2 . TYR B 1 189 ? 44.864 87.462 81.214 1.00 33.96 ? 225 TYR B CE2 1 ATOM 7463 C CZ . TYR B 1 189 ? 44.672 87.720 79.881 1.00 33.59 ? 225 TYR B CZ 1 ATOM 7464 O OH . TYR B 1 189 ? 43.686 88.590 79.492 1.00 36.19 ? 225 TYR B OH 1 ATOM 7465 N N . ALA B 1 190 ? 50.159 85.491 79.126 1.00 29.31 ? 226 ALA B N 1 ATOM 7466 C CA . ALA B 1 190 ? 50.512 86.017 77.815 1.00 30.95 ? 226 ALA B CA 1 ATOM 7467 C C . ALA B 1 190 ? 49.483 85.605 76.773 1.00 30.08 ? 226 ALA B C 1 ATOM 7468 O O . ALA B 1 190 ? 48.805 84.581 76.911 1.00 31.18 ? 226 ALA B O 1 ATOM 7469 C CB . ALA B 1 190 ? 51.921 85.567 77.396 1.00 30.20 ? 226 ALA B CB 1 ATOM 7470 N N . GLN B 1 191 ? 49.359 86.425 75.740 1.00 27.26 ? 227 GLN B N 1 ATOM 7471 C CA . GLN B 1 191 ? 48.508 86.113 74.612 1.00 27.54 ? 227 GLN B CA 1 ATOM 7472 C C . GLN B 1 191 ? 49.351 86.118 73.331 1.00 29.74 ? 227 GLN B C 1 ATOM 7473 O O . GLN B 1 191 ? 50.089 87.063 73.068 1.00 29.87 ? 227 GLN B O 1 ATOM 7474 C CB . GLN B 1 191 ? 47.393 87.143 74.487 1.00 30.50 ? 227 GLN B CB 1 ATOM 7475 C CG . GLN B 1 191 ? 46.474 86.894 73.310 1.00 29.85 ? 227 GLN B CG 1 ATOM 7476 C CD . GLN B 1 191 ? 45.634 88.101 72.975 1.00 34.99 ? 227 GLN B CD 1 ATOM 7477 O OE1 . GLN B 1 191 ? 46.097 89.029 72.309 1.00 35.29 ? 227 GLN B OE1 1 ATOM 7478 N NE2 . GLN B 1 191 ? 44.391 88.100 73.437 1.00 30.06 ? 227 GLN B NE2 1 ATOM 7479 N N . PHE B 1 192 ? 49.243 85.064 72.534 1.00 28.37 ? 228 PHE B N 1 ATOM 7480 C CA . PHE B 1 192 ? 50.036 84.981 71.314 1.00 28.54 ? 228 PHE B CA 1 ATOM 7481 C C . PHE B 1 192 ? 49.133 85.063 70.105 1.00 28.07 ? 228 PHE B C 1 ATOM 7482 O O . PHE B 1 192 ? 48.022 84.526 70.107 1.00 29.79 ? 228 PHE B O 1 ATOM 7483 C CB . PHE B 1 192 ? 50.851 83.692 71.293 1.00 29.11 ? 228 PHE B CB 1 ATOM 7484 C CG . PHE B 1 192 ? 51.714 83.522 72.499 1.00 26.62 ? 228 PHE B CG 1 ATOM 7485 C CD1 . PHE B 1 192 ? 52.955 84.114 72.561 1.00 28.31 ? 228 PHE B CD1 1 ATOM 7486 C CD2 . PHE B 1 192 ? 51.262 82.814 73.590 1.00 29.79 ? 228 PHE B CD2 1 ATOM 7487 C CE1 . PHE B 1 192 ? 53.747 83.967 73.687 1.00 27.49 ? 228 PHE B CE1 1 ATOM 7488 C CE2 . PHE B 1 192 ? 52.040 82.671 74.699 1.00 28.98 ? 228 PHE B CE2 1 ATOM 7489 C CZ . PHE B 1 192 ? 53.287 83.244 74.746 1.00 26.81 ? 228 PHE B CZ 1 ATOM 7490 N N . ASN B 1 193 ? 49.613 85.750 69.080 1.00 29.86 ? 229 ASN B N 1 ATOM 7491 C CA . ASN B 1 193 ? 48.832 85.974 67.883 1.00 29.07 ? 229 ASN B CA 1 ATOM 7492 C C . ASN B 1 193 ? 49.605 85.415 66.694 1.00 30.13 ? 229 ASN B C 1 ATOM 7493 O O . ASN B 1 193 ? 50.638 85.963 66.304 1.00 28.70 ? 229 ASN B O 1 ATOM 7494 C CB . ASN B 1 193 ? 48.574 87.477 67.711 1.00 34.43 ? 229 ASN B CB 1 ATOM 7495 C CG . ASN B 1 193 ? 47.529 87.769 66.648 1.00 35.94 ? 229 ASN B CG 1 ATOM 7496 O OD1 . ASN B 1 193 ? 47.392 87.015 65.681 1.00 30.74 ? 229 ASN B OD1 1 ATOM 7497 N ND2 . ASN B 1 193 ? 46.775 88.856 66.836 1.00 38.20 ? 229 ASN B ND2 1 ATOM 7498 N N . ASP B 1 194 ? 49.120 84.311 66.136 1.00 30.27 ? 230 ASP B N 1 ATOM 7499 C CA . ASP B 1 194 ? 49.805 83.652 65.021 1.00 32.02 ? 230 ASP B CA 1 ATOM 7500 C C . ASP B 1 194 ? 49.153 83.928 63.662 1.00 36.71 ? 230 ASP B C 1 ATOM 7501 O O . ASP B 1 194 ? 49.440 83.253 62.655 1.00 34.99 ? 230 ASP B O 1 ATOM 7502 C CB . ASP B 1 194 ? 49.905 82.142 65.275 1.00 32.90 ? 230 ASP B CB 1 ATOM 7503 C CG . ASP B 1 194 ? 50.980 81.803 66.295 1.00 35.53 ? 230 ASP B CG 1 ATOM 7504 O OD1 . ASP B 1 194 ? 51.049 82.502 67.328 1.00 37.42 ? 230 ASP B OD1 1 ATOM 7505 O OD2 . ASP B 1 194 ? 51.777 80.874 66.058 1.00 32.68 ? 230 ASP B OD2 1 ATOM 7506 N N . THR B 1 195 ? 48.287 84.933 63.637 1.00 32.53 ? 231 THR B N 1 ATOM 7507 C CA . THR B 1 195 ? 47.569 85.316 62.417 1.00 39.29 ? 231 THR B CA 1 ATOM 7508 C C . THR B 1 195 ? 48.358 85.192 61.114 1.00 37.89 ? 231 THR B C 1 ATOM 7509 O O . THR B 1 195 ? 47.872 84.584 60.168 1.00 42.70 ? 231 THR B O 1 ATOM 7510 C CB . THR B 1 195 ? 46.980 86.739 62.529 1.00 37.96 ? 231 THR B CB 1 ATOM 7511 O OG1 . THR B 1 195 ? 45.835 86.695 63.387 1.00 41.17 ? 231 THR B OG1 1 ATOM 7512 C CG2 . THR B 1 195 ? 46.547 87.253 61.153 1.00 46.09 ? 231 THR B CG2 1 ATOM 7513 N N . GLU B 1 196 ? 49.562 85.753 61.058 1.00 34.31 ? 232 GLU B N 1 ATOM 7514 C CA . GLU B 1 196 ? 50.314 85.764 59.802 1.00 37.97 ? 232 GLU B CA 1 ATOM 7515 C C . GLU B 1 196 ? 51.505 84.801 59.762 1.00 34.92 ? 232 GLU B C 1 ATOM 7516 O O . GLU B 1 196 ? 52.351 84.889 58.889 1.00 33.97 ? 232 GLU B O 1 ATOM 7517 C CB . GLU B 1 196 ? 50.760 87.190 59.465 1.00 42.66 ? 232 GLU B CB 1 ATOM 7518 C CG . GLU B 1 196 ? 49.683 88.228 59.771 1.00 48.08 ? 232 GLU B CG 1 ATOM 7519 C CD . GLU B 1 196 ? 50.021 89.619 59.257 1.00 59.01 ? 232 GLU B CD 1 ATOM 7520 O OE1 . GLU B 1 196 ? 50.024 89.816 58.017 1.00 56.69 ? 232 GLU B OE1 1 ATOM 7521 O OE2 . GLU B 1 196 ? 50.270 90.514 60.096 1.00 60.47 ? 232 GLU B OE2 1 ATOM 7522 N N . VAL B 1 197 ? 51.572 83.874 60.707 1.00 31.17 ? 233 VAL B N 1 ATOM 7523 C CA . VAL B 1 197 ? 52.645 82.902 60.696 1.00 29.83 ? 233 VAL B CA 1 ATOM 7524 C C . VAL B 1 197 ? 52.280 81.840 59.665 1.00 24.59 ? 233 VAL B C 1 ATOM 7525 O O . VAL B 1 197 ? 51.153 81.370 59.667 1.00 29.42 ? 233 VAL B O 1 ATOM 7526 C CB . VAL B 1 197 ? 52.777 82.244 62.082 1.00 30.05 ? 233 VAL B CB 1 ATOM 7527 C CG1 . VAL B 1 197 ? 53.856 81.199 62.057 1.00 28.34 ? 233 VAL B CG1 1 ATOM 7528 C CG2 . VAL B 1 197 ? 53.077 83.303 63.144 1.00 32.45 ? 233 VAL B CG2 1 ATOM 7529 N N . PRO B 1 198 ? 53.223 81.467 58.780 1.00 22.69 ? 234 PRO B N 1 ATOM 7530 C CA . PRO B 1 198 ? 52.929 80.454 57.754 1.00 29.06 ? 234 PRO B CA 1 ATOM 7531 C C . PRO B 1 198 ? 52.810 79.076 58.378 1.00 29.38 ? 234 PRO B C 1 ATOM 7532 O O . PRO B 1 198 ? 53.315 78.867 59.476 1.00 30.24 ? 234 PRO B O 1 ATOM 7533 C CB . PRO B 1 198 ? 54.163 80.495 56.837 1.00 31.59 ? 234 PRO B CB 1 ATOM 7534 C CG . PRO B 1 198 ? 54.879 81.784 57.163 1.00 28.06 ? 234 PRO B CG 1 ATOM 7535 C CD . PRO B 1 198 ? 54.565 82.050 58.615 1.00 26.40 ? 234 PRO B CD 1 ATOM 7536 N N . LEU B 1 199 ? 52.184 78.141 57.676 1.00 27.76 ? 235 LEU B N 1 ATOM 7537 C CA . LEU B 1 199 ? 51.936 76.824 58.222 1.00 29.78 ? 235 LEU B CA 1 ATOM 7538 C C . LEU B 1 199 ? 52.853 75.787 57.591 1.00 29.96 ? 235 LEU B C 1 ATOM 7539 O O . LEU B 1 199 ? 53.045 75.778 56.383 1.00 32.28 ? 235 LEU B O 1 ATOM 7540 C CB . LEU B 1 199 ? 50.493 76.438 57.942 1.00 30.71 ? 235 LEU B CB 1 ATOM 7541 C CG . LEU B 1 199 ? 49.438 77.461 58.358 1.00 31.69 ? 235 LEU B CG 1 ATOM 7542 C CD1 . LEU B 1 199 ? 48.177 77.260 57.519 1.00 36.49 ? 235 LEU B CD1 1 ATOM 7543 C CD2 . LEU B 1 199 ? 49.123 77.375 59.838 1.00 29.49 ? 235 LEU B CD2 1 ATOM 7544 N N . ILE B 1 200 ? 53.438 74.927 58.414 1.00 29.91 ? 236 ILE B N 1 ATOM 7545 C CA . ILE B 1 200 ? 54.055 73.715 57.905 1.00 26.54 ? 236 ILE B CA 1 ATOM 7546 C C . ILE B 1 200 ? 52.915 72.723 57.726 1.00 30.15 ? 236 ILE B C 1 ATOM 7547 O O . ILE B 1 200 ? 52.072 72.566 58.611 1.00 32.48 ? 236 ILE B O 1 ATOM 7548 C CB . ILE B 1 200 ? 55.127 73.131 58.870 1.00 27.37 ? 236 ILE B CB 1 ATOM 7549 C CG1 . ILE B 1 200 ? 55.772 71.881 58.258 1.00 28.20 ? 236 ILE B CG1 1 ATOM 7550 C CG2 . ILE B 1 200 ? 54.528 72.798 60.244 1.00 25.93 ? 236 ILE B CG2 1 ATOM 7551 C CD1 . ILE B 1 200 ? 56.474 72.137 56.920 1.00 26.48 ? 236 ILE B CD1 1 ATOM 7552 N N . GLU B 1 201 ? 52.870 72.072 56.576 1.00 28.92 ? 237 GLU B N 1 ATOM 7553 C CA . GLU B 1 201 ? 51.856 71.068 56.316 1.00 31.73 ? 237 GLU B CA 1 ATOM 7554 C C . GLU B 1 201 ? 52.541 69.737 56.032 1.00 28.91 ? 237 GLU B C 1 ATOM 7555 O O . GLU B 1 201 ? 53.553 69.701 55.338 1.00 30.46 ? 237 GLU B O 1 ATOM 7556 C CB . GLU B 1 201 ? 50.971 71.515 55.137 1.00 30.71 ? 237 GLU B CB 1 ATOM 7557 C CG . GLU B 1 201 ? 50.419 72.951 55.336 1.00 35.20 ? 237 GLU B CG 1 ATOM 7558 C CD . GLU B 1 201 ? 49.402 73.403 54.282 1.00 44.81 ? 237 GLU B CD 1 ATOM 7559 O OE1 . GLU B 1 201 ? 49.122 72.661 53.320 1.00 46.17 ? 237 GLU B OE1 1 ATOM 7560 O OE2 . GLU B 1 201 ? 48.874 74.524 54.413 1.00 49.17 ? 237 GLU B OE2 1 ATOM 7561 N N . TYR B 1 202 ? 52.011 68.647 56.577 1.00 26.45 ? 238 TYR B N 1 ATOM 7562 C CA . TYR B 1 202 ? 52.551 67.327 56.267 1.00 27.78 ? 238 TYR B CA 1 ATOM 7563 C C . TYR B 1 202 ? 51.465 66.283 56.442 1.00 32.43 ? 238 TYR B C 1 ATOM 7564 O O . TYR B 1 202 ? 50.473 66.520 57.140 1.00 28.24 ? 238 TYR B O 1 ATOM 7565 C CB . TYR B 1 202 ? 53.786 67.003 57.119 1.00 28.02 ? 238 TYR B CB 1 ATOM 7566 C CG . TYR B 1 202 ? 53.555 67.089 58.620 1.00 28.21 ? 238 TYR B CG 1 ATOM 7567 C CD1 . TYR B 1 202 ? 53.113 65.990 59.345 1.00 26.97 ? 238 TYR B CD1 1 ATOM 7568 C CD2 . TYR B 1 202 ? 53.785 68.277 59.306 1.00 29.43 ? 238 TYR B CD2 1 ATOM 7569 C CE1 . TYR B 1 202 ? 52.892 66.083 60.724 1.00 28.70 ? 238 TYR B CE1 1 ATOM 7570 C CE2 . TYR B 1 202 ? 53.579 68.381 60.664 1.00 27.56 ? 238 TYR B CE2 1 ATOM 7571 C CZ . TYR B 1 202 ? 53.136 67.285 61.371 1.00 28.74 ? 238 TYR B CZ 1 ATOM 7572 O OH . TYR B 1 202 ? 52.926 67.403 62.726 1.00 31.59 ? 238 TYR B OH 1 ATOM 7573 N N . SER B 1 203 ? 51.625 65.139 55.785 1.00 25.94 ? 239 SER B N 1 ATOM 7574 C CA . SER B 1 203 ? 50.597 64.108 55.838 1.00 29.86 ? 239 SER B CA 1 ATOM 7575 C C . SER B 1 203 ? 50.725 63.282 57.100 1.00 25.94 ? 239 SER B C 1 ATOM 7576 O O . SER B 1 203 ? 51.827 63.051 57.605 1.00 30.94 ? 239 SER B O 1 ATOM 7577 C CB . SER B 1 203 ? 50.681 63.179 54.618 1.00 31.06 ? 239 SER B CB 1 ATOM 7578 O OG . SER B 1 203 ? 50.680 63.913 53.411 1.00 33.66 ? 239 SER B OG 1 ATOM 7579 N N . PHE B 1 204 ? 49.590 62.839 57.617 1.00 28.79 ? 240 PHE B N 1 ATOM 7580 C CA . PHE B 1 204 ? 49.571 61.906 58.731 1.00 24.80 ? 240 PHE B CA 1 ATOM 7581 C C . PHE B 1 204 ? 48.724 60.726 58.273 1.00 28.31 ? 240 PHE B C 1 ATOM 7582 O O . PHE B 1 204 ? 47.565 60.896 57.880 1.00 25.87 ? 240 PHE B O 1 ATOM 7583 C CB . PHE B 1 204 ? 48.970 62.554 59.988 1.00 26.73 ? 240 PHE B CB 1 ATOM 7584 C CG . PHE B 1 204 ? 49.148 61.720 61.226 1.00 30.48 ? 240 PHE B CG 1 ATOM 7585 C CD1 . PHE B 1 204 ? 50.328 61.786 61.960 1.00 29.81 ? 240 PHE B CD1 1 ATOM 7586 C CD2 . PHE B 1 204 ? 48.162 60.844 61.637 1.00 30.63 ? 240 PHE B CD2 1 ATOM 7587 C CE1 . PHE B 1 204 ? 50.509 61.001 63.090 1.00 31.74 ? 240 PHE B CE1 1 ATOM 7588 C CE2 . PHE B 1 204 ? 48.340 60.053 62.776 1.00 32.83 ? 240 PHE B CE2 1 ATOM 7589 C CZ . PHE B 1 204 ? 49.515 60.134 63.498 1.00 32.98 ? 240 PHE B CZ 1 ATOM 7590 N N . TYR B 1 205 ? 49.292 59.528 58.301 1.00 25.36 ? 241 TYR B N 1 ATOM 7591 C CA . TYR B 1 205 ? 48.623 58.386 57.674 1.00 26.01 ? 241 TYR B CA 1 ATOM 7592 C C . TYR B 1 205 ? 47.656 57.641 58.606 1.00 29.34 ? 241 TYR B C 1 ATOM 7593 O O . TYR B 1 205 ? 46.668 57.063 58.146 1.00 27.19 ? 241 TYR B O 1 ATOM 7594 C CB . TYR B 1 205 ? 49.665 57.465 57.044 1.00 27.79 ? 241 TYR B CB 1 ATOM 7595 C CG . TYR B 1 205 ? 50.531 58.231 56.065 1.00 27.08 ? 241 TYR B CG 1 ATOM 7596 C CD1 . TYR B 1 205 ? 50.080 58.499 54.774 1.00 26.59 ? 241 TYR B CD1 1 ATOM 7597 C CD2 . TYR B 1 205 ? 51.762 58.742 56.448 1.00 24.33 ? 241 TYR B CD2 1 ATOM 7598 C CE1 . TYR B 1 205 ? 50.842 59.219 53.886 1.00 23.19 ? 241 TYR B CE1 1 ATOM 7599 C CE2 . TYR B 1 205 ? 52.555 59.458 55.547 1.00 26.64 ? 241 TYR B CE2 1 ATOM 7600 C CZ . TYR B 1 205 ? 52.083 59.698 54.273 1.00 24.85 ? 241 TYR B CZ 1 ATOM 7601 O OH . TYR B 1 205 ? 52.854 60.420 53.375 1.00 31.27 ? 241 TYR B OH 1 ATOM 7602 N N . SER B 1 206 ? 47.937 57.680 59.906 1.00 26.08 ? 242 SER B N 1 ATOM 7603 C CA . SER B 1 206 ? 47.059 57.093 60.924 1.00 27.74 ? 242 SER B CA 1 ATOM 7604 C C . SER B 1 206 ? 46.915 55.586 60.763 1.00 31.24 ? 242 SER B C 1 ATOM 7605 O O . SER B 1 206 ? 47.720 54.943 60.082 1.00 33.67 ? 242 SER B O 1 ATOM 7606 C CB . SER B 1 206 ? 45.677 57.754 60.898 1.00 30.13 ? 242 SER B CB 1 ATOM 7607 O OG . SER B 1 206 ? 44.923 57.409 62.051 1.00 34.96 ? 242 SER B OG 1 ATOM 7608 N N . ASP B 1 207 ? 45.887 55.021 61.385 1.00 29.35 ? 243 ASP B N 1 ATOM 7609 C CA . ASP B 1 207 ? 45.638 53.588 61.288 1.00 32.79 ? 243 ASP B CA 1 ATOM 7610 C C . ASP B 1 207 ? 45.297 53.207 59.851 1.00 32.92 ? 243 ASP B C 1 ATOM 7611 O O . ASP B 1 207 ? 44.829 54.027 59.062 1.00 28.50 ? 243 ASP B O 1 ATOM 7612 C CB . ASP B 1 207 ? 44.499 53.140 62.225 1.00 38.44 ? 243 ASP B CB 1 ATOM 7613 C CG . ASP B 1 207 ? 44.859 53.266 63.719 1.00 52.59 ? 243 ASP B CG 1 ATOM 7614 O OD1 . ASP B 1 207 ? 46.061 53.200 64.082 1.00 52.14 ? 243 ASP B OD1 1 ATOM 7615 O OD2 . ASP B 1 207 ? 43.926 53.427 64.540 1.00 55.59 ? 243 ASP B OD2 1 ATOM 7616 N N . GLU B 1 208 ? 45.531 51.945 59.539 1.00 34.61 ? 244 GLU B N 1 ATOM 7617 C CA . GLU B 1 208 ? 45.274 51.361 58.233 1.00 32.26 ? 244 GLU B CA 1 ATOM 7618 C C . GLU B 1 208 ? 43.872 51.682 57.716 1.00 35.21 ? 244 GLU B C 1 ATOM 7619 O O . GLU B 1 208 ? 43.657 51.802 56.512 1.00 32.78 ? 244 GLU B O 1 ATOM 7620 C CB . GLU B 1 208 ? 45.401 49.854 58.397 1.00 38.91 ? 244 GLU B CB 1 ATOM 7621 C CG . GLU B 1 208 ? 45.923 49.113 57.216 1.00 43.85 ? 244 GLU B CG 1 ATOM 7622 C CD . GLU B 1 208 ? 45.999 47.625 57.495 1.00 44.80 ? 244 GLU B CD 1 ATOM 7623 O OE1 . GLU B 1 208 ? 46.476 47.251 58.594 1.00 41.73 ? 244 GLU B OE1 1 ATOM 7624 O OE2 . GLU B 1 208 ? 45.564 46.838 56.623 1.00 48.36 ? 244 GLU B OE2 1 ATOM 7625 N N . SER B 1 209 ? 42.918 51.826 58.629 1.00 29.69 ? 245 SER B N 1 ATOM 7626 C CA . SER B 1 209 ? 41.515 51.996 58.247 1.00 33.12 ? 245 SER B CA 1 ATOM 7627 C C . SER B 1 209 ? 41.189 53.371 57.678 1.00 30.16 ? 245 SER B C 1 ATOM 7628 O O . SER B 1 209 ? 40.148 53.558 57.060 1.00 32.75 ? 245 SER B O 1 ATOM 7629 C CB . SER B 1 209 ? 40.598 51.707 59.449 1.00 33.83 ? 245 SER B CB 1 ATOM 7630 O OG . SER B 1 209 ? 40.971 52.514 60.559 1.00 37.94 ? 245 SER B OG 1 ATOM 7631 N N . LEU B 1 210 ? 42.069 54.340 57.891 1.00 28.74 ? 246 LEU B N 1 ATOM 7632 C CA . LEU B 1 210 ? 41.843 55.681 57.370 1.00 28.21 ? 246 LEU B CA 1 ATOM 7633 C C . LEU B 1 210 ? 42.087 55.685 55.864 1.00 28.68 ? 246 LEU B C 1 ATOM 7634 O O . LEU B 1 210 ? 43.206 55.428 55.417 1.00 27.45 ? 246 LEU B O 1 ATOM 7635 C CB . LEU B 1 210 ? 42.763 56.686 58.069 1.00 26.92 ? 246 LEU B CB 1 ATOM 7636 C CG . LEU B 1 210 ? 42.547 58.128 57.634 1.00 28.11 ? 246 LEU B CG 1 ATOM 7637 C CD1 . LEU B 1 210 ? 41.086 58.494 57.786 1.00 33.70 ? 246 LEU B CD1 1 ATOM 7638 C CD2 . LEU B 1 210 ? 43.428 59.077 58.443 1.00 29.45 ? 246 LEU B CD2 1 ATOM 7639 N N . GLN B 1 211 ? 41.043 55.968 55.082 1.00 27.48 ? 247 GLN B N 1 ATOM 7640 C CA . GLN B 1 211 ? 41.134 55.845 53.627 1.00 26.44 ? 247 GLN B CA 1 ATOM 7641 C C . GLN B 1 211 ? 41.968 56.949 52.967 1.00 28.36 ? 247 GLN B C 1 ATOM 7642 O O . GLN B 1 211 ? 42.774 56.677 52.077 1.00 22.38 ? 247 GLN B O 1 ATOM 7643 C CB . GLN B 1 211 ? 39.742 55.759 52.981 1.00 28.51 ? 247 GLN B CB 1 ATOM 7644 C CG . GLN B 1 211 ? 39.815 55.311 51.532 1.00 27.77 ? 247 GLN B CG 1 ATOM 7645 C CD . GLN B 1 211 ? 38.445 55.171 50.887 1.00 30.02 ? 247 GLN B CD 1 ATOM 7646 O OE1 . GLN B 1 211 ? 37.500 55.862 51.264 1.00 29.82 ? 247 GLN B OE1 1 ATOM 7647 N NE2 . GLN B 1 211 ? 38.336 54.276 49.906 1.00 23.54 ? 247 GLN B NE2 1 ATOM 7648 N N . TYR B 1 212 ? 41.780 58.188 53.409 1.00 24.94 ? 248 TYR B N 1 ATOM 7649 C CA . TYR B 1 212 ? 42.535 59.316 52.870 1.00 26.43 ? 248 TYR B CA 1 ATOM 7650 C C . TYR B 1 212 ? 43.465 59.856 53.956 1.00 29.69 ? 248 TYR B C 1 ATOM 7651 O O . TYR B 1 212 ? 43.025 60.107 55.066 1.00 29.18 ? 248 TYR B O 1 ATOM 7652 C CB . TYR B 1 212 ? 41.580 60.439 52.438 1.00 27.17 ? 248 TYR B CB 1 ATOM 7653 C CG . TYR B 1 212 ? 40.820 60.158 51.148 1.00 31.34 ? 248 TYR B CG 1 ATOM 7654 C CD1 . TYR B 1 212 ? 39.623 59.423 51.145 1.00 27.78 ? 248 TYR B CD1 1 ATOM 7655 C CD2 . TYR B 1 212 ? 41.309 60.615 49.930 1.00 27.71 ? 248 TYR B CD2 1 ATOM 7656 C CE1 . TYR B 1 212 ? 38.937 59.155 49.941 1.00 27.19 ? 248 TYR B CE1 1 ATOM 7657 C CE2 . TYR B 1 212 ? 40.626 60.357 48.735 1.00 27.75 ? 248 TYR B CE2 1 ATOM 7658 C CZ . TYR B 1 212 ? 39.450 59.632 48.743 1.00 27.66 ? 248 TYR B CZ 1 ATOM 7659 O OH . TYR B 1 212 ? 38.803 59.404 47.528 1.00 26.17 ? 248 TYR B OH 1 ATOM 7660 N N . PRO B 1 213 ? 44.752 60.044 53.640 1.00 30.71 ? 249 PRO B N 1 ATOM 7661 C CA . PRO B 1 213 ? 45.669 60.607 54.634 1.00 31.13 ? 249 PRO B CA 1 ATOM 7662 C C . PRO B 1 213 ? 45.193 61.970 55.089 1.00 32.31 ? 249 PRO B C 1 ATOM 7663 O O . PRO B 1 213 ? 44.560 62.693 54.317 1.00 27.67 ? 249 PRO B O 1 ATOM 7664 C CB . PRO B 1 213 ? 46.972 60.769 53.852 1.00 29.06 ? 249 PRO B CB 1 ATOM 7665 C CG . PRO B 1 213 ? 46.862 59.755 52.732 1.00 30.06 ? 249 PRO B CG 1 ATOM 7666 C CD . PRO B 1 213 ? 45.423 59.756 52.359 1.00 28.15 ? 249 PRO B CD 1 ATOM 7667 N N . LYS B 1 214 ? 45.507 62.316 56.330 1.00 31.47 ? 250 LYS B N 1 ATOM 7668 C CA . LYS B 1 214 ? 45.145 63.611 56.894 1.00 33.33 ? 250 LYS B CA 1 ATOM 7669 C C . LYS B 1 214 ? 46.292 64.588 56.647 1.00 33.42 ? 250 LYS B C 1 ATOM 7670 O O . LYS B 1 214 ? 47.445 64.175 56.588 1.00 34.84 ? 250 LYS B O 1 ATOM 7671 C CB . LYS B 1 214 ? 44.889 63.459 58.402 1.00 34.07 ? 250 LYS B CB 1 ATOM 7672 C CG . LYS B 1 214 ? 44.348 64.723 59.069 1.00 45.25 ? 250 LYS B CG 1 ATOM 7673 C CD . LYS B 1 214 ? 44.390 64.622 60.595 1.00 52.99 ? 250 LYS B CD 1 ATOM 7674 N N . THR B 1 215 ? 45.985 65.871 56.470 1.00 31.76 ? 251 THR B N 1 ATOM 7675 C CA . THR B 1 215 ? 47.031 66.881 56.382 1.00 30.77 ? 251 THR B CA 1 ATOM 7676 C C . THR B 1 215 ? 47.080 67.684 57.682 1.00 32.26 ? 251 THR B C 1 ATOM 7677 O O . THR B 1 215 ? 46.101 68.316 58.070 1.00 30.53 ? 251 THR B O 1 ATOM 7678 C CB . THR B 1 215 ? 46.857 67.820 55.158 1.00 33.38 ? 251 THR B CB 1 ATOM 7679 O OG1 . THR B 1 215 ? 47.055 67.070 53.952 1.00 34.11 ? 251 THR B OG1 1 ATOM 7680 C CG2 . THR B 1 215 ? 47.889 68.945 55.194 1.00 32.77 ? 251 THR B CG2 1 ATOM 7681 N N . VAL B 1 216 ? 48.219 67.627 58.361 1.00 29.96 ? 252 VAL B N 1 ATOM 7682 C CA . VAL B 1 216 ? 48.421 68.368 59.593 1.00 27.45 ? 252 VAL B CA 1 ATOM 7683 C C . VAL B 1 216 ? 48.987 69.721 59.210 1.00 27.93 ? 252 VAL B C 1 ATOM 7684 O O . VAL B 1 216 ? 49.848 69.808 58.339 1.00 28.89 ? 252 VAL B O 1 ATOM 7685 C CB . VAL B 1 216 ? 49.406 67.636 60.512 1.00 30.68 ? 252 VAL B CB 1 ATOM 7686 C CG1 . VAL B 1 216 ? 49.693 68.460 61.755 1.00 29.03 ? 252 VAL B CG1 1 ATOM 7687 C CG2 . VAL B 1 216 ? 48.840 66.286 60.914 1.00 27.95 ? 252 VAL B CG2 1 ATOM 7688 N N . ARG B 1 217 ? 48.495 70.773 59.849 1.00 25.10 ? 253 ARG B N 1 ATOM 7689 C CA . ARG B 1 217 ? 48.904 72.139 59.548 1.00 28.72 ? 253 ARG B CA 1 ATOM 7690 C C . ARG B 1 217 ? 49.210 72.886 60.834 1.00 27.36 ? 253 ARG B C 1 ATOM 7691 O O . ARG B 1 217 ? 48.335 73.042 61.672 1.00 31.60 ? 253 ARG B O 1 ATOM 7692 C CB . ARG B 1 217 ? 47.774 72.869 58.827 1.00 29.92 ? 253 ARG B CB 1 ATOM 7693 C CG . ARG B 1 217 ? 47.794 72.711 57.333 1.00 40.44 ? 253 ARG B CG 1 ATOM 7694 C CD . ARG B 1 217 ? 46.528 73.287 56.741 1.00 45.80 ? 253 ARG B CD 1 ATOM 7695 N NE . ARG B 1 217 ? 45.459 72.316 56.912 1.00 53.43 ? 253 ARG B NE 1 ATOM 7696 C CZ . ARG B 1 217 ? 45.177 71.387 56.002 1.00 54.44 ? 253 ARG B CZ 1 ATOM 7697 N NH1 . ARG B 1 217 ? 45.884 71.354 54.876 1.00 49.16 ? 253 ARG B NH1 1 ATOM 7698 N NH2 . ARG B 1 217 ? 44.198 70.505 56.212 1.00 49.33 ? 253 ARG B NH2 1 ATOM 7699 N N . VAL B 1 218 ? 50.444 73.347 60.986 1.00 26.44 ? 254 VAL B N 1 ATOM 7700 C CA . VAL B 1 218 ? 50.881 73.976 62.232 1.00 25.56 ? 254 VAL B CA 1 ATOM 7701 C C . VAL B 1 218 ? 51.519 75.325 61.951 1.00 26.50 ? 254 VAL B C 1 ATOM 7702 O O . VAL B 1 218 ? 52.484 75.389 61.201 1.00 28.22 ? 254 VAL B O 1 ATOM 7703 C CB . VAL B 1 218 ? 51.962 73.125 62.894 1.00 27.26 ? 254 VAL B CB 1 ATOM 7704 C CG1 . VAL B 1 218 ? 52.288 73.657 64.294 1.00 27.86 ? 254 VAL B CG1 1 ATOM 7705 C CG2 . VAL B 1 218 ? 51.521 71.678 62.951 1.00 30.23 ? 254 VAL B CG2 1 ATOM 7706 N N . PRO B 1 219 ? 51.013 76.405 62.572 1.00 27.97 ? 255 PRO B N 1 ATOM 7707 C CA . PRO B 1 219 ? 51.721 77.688 62.457 1.00 25.76 ? 255 PRO B CA 1 ATOM 7708 C C . PRO B 1 219 ? 53.142 77.544 62.973 1.00 27.63 ? 255 PRO B C 1 ATOM 7709 O O . PRO B 1 219 ? 53.350 77.221 64.140 1.00 26.70 ? 255 PRO B O 1 ATOM 7710 C CB . PRO B 1 219 ? 50.922 78.620 63.373 1.00 28.86 ? 255 PRO B CB 1 ATOM 7711 C CG . PRO B 1 219 ? 49.550 77.995 63.439 1.00 29.91 ? 255 PRO B CG 1 ATOM 7712 C CD . PRO B 1 219 ? 49.797 76.514 63.393 1.00 30.48 ? 255 PRO B CD 1 ATOM 7713 N N . TYR B 1 220 ? 54.114 77.773 62.104 1.00 26.58 ? 256 TYR B N 1 ATOM 7714 C CA . TYR B 1 220 ? 55.501 77.487 62.424 1.00 24.89 ? 256 TYR B CA 1 ATOM 7715 C C . TYR B 1 220 ? 56.373 78.424 61.607 1.00 24.74 ? 256 TYR B C 1 ATOM 7716 O O . TYR B 1 220 ? 56.508 78.240 60.403 1.00 27.35 ? 256 TYR B O 1 ATOM 7717 C CB . TYR B 1 220 ? 55.796 76.028 62.071 1.00 23.13 ? 256 TYR B CB 1 ATOM 7718 C CG . TYR B 1 220 ? 57.215 75.541 62.284 1.00 24.82 ? 256 TYR B CG 1 ATOM 7719 C CD1 . TYR B 1 220 ? 58.284 76.095 61.593 1.00 23.22 ? 256 TYR B CD1 1 ATOM 7720 C CD2 . TYR B 1 220 ? 57.473 74.477 63.142 1.00 22.41 ? 256 TYR B CD2 1 ATOM 7721 C CE1 . TYR B 1 220 ? 59.577 75.625 61.777 1.00 20.96 ? 256 TYR B CE1 1 ATOM 7722 C CE2 . TYR B 1 220 ? 58.747 74.007 63.325 1.00 21.42 ? 256 TYR B CE2 1 ATOM 7723 C CZ . TYR B 1 220 ? 59.792 74.576 62.642 1.00 23.34 ? 256 TYR B CZ 1 ATOM 7724 O OH . TYR B 1 220 ? 61.061 74.089 62.843 1.00 23.50 ? 256 TYR B OH 1 ATOM 7725 N N . PRO B 1 221 ? 56.979 79.427 62.262 1.00 27.03 ? 257 PRO B N 1 ATOM 7726 C CA . PRO B 1 221 ? 57.873 80.379 61.580 1.00 22.93 ? 257 PRO B CA 1 ATOM 7727 C C . PRO B 1 221 ? 59.239 79.758 61.301 1.00 26.81 ? 257 PRO B C 1 ATOM 7728 O O . PRO B 1 221 ? 59.969 79.462 62.269 1.00 26.44 ? 257 PRO B O 1 ATOM 7729 C CB . PRO B 1 221 ? 58.028 81.501 62.615 1.00 24.90 ? 257 PRO B CB 1 ATOM 7730 C CG . PRO B 1 221 ? 57.893 80.771 63.974 1.00 23.65 ? 257 PRO B CG 1 ATOM 7731 C CD . PRO B 1 221 ? 56.892 79.665 63.723 1.00 25.98 ? 257 PRO B CD 1 ATOM 7732 N N . LYS B 1 222 ? 59.571 79.516 60.025 1.00 23.07 ? 258 LYS B N 1 ATOM 7733 C CA . LYS B 1 222 ? 60.934 79.129 59.665 1.00 22.90 ? 258 LYS B CA 1 ATOM 7734 C C . LYS B 1 222 ? 61.820 80.391 59.646 1.00 26.98 ? 258 LYS B C 1 ATOM 7735 O O . LYS B 1 222 ? 61.320 81.502 59.774 1.00 27.66 ? 258 LYS B O 1 ATOM 7736 C CB . LYS B 1 222 ? 60.963 78.382 58.325 1.00 24.78 ? 258 LYS B CB 1 ATOM 7737 C CG . LYS B 1 222 ? 60.214 77.057 58.347 1.00 23.37 ? 258 LYS B CG 1 ATOM 7738 C CD . LYS B 1 222 ? 60.138 76.418 56.951 1.00 24.66 ? 258 LYS B CD 1 ATOM 7739 C CE . LYS B 1 222 ? 59.487 75.044 57.001 1.00 23.75 ? 258 LYS B CE 1 ATOM 7740 N NZ . LYS B 1 222 ? 60.453 73.944 57.284 1.00 21.94 ? 258 LYS B NZ 1 ATOM 7741 N N . ALA B 1 223 ? 63.129 80.224 59.508 1.00 27.17 ? 259 ALA B N 1 ATOM 7742 C CA . ALA B 1 223 ? 64.048 81.340 59.708 1.00 28.06 ? 259 ALA B CA 1 ATOM 7743 C C . ALA B 1 223 ? 63.727 82.497 58.768 1.00 29.34 ? 259 ALA B C 1 ATOM 7744 O O . ALA B 1 223 ? 63.562 82.301 57.565 1.00 29.41 ? 259 ALA B O 1 ATOM 7745 C CB . ALA B 1 223 ? 65.494 80.887 59.534 1.00 25.77 ? 259 ALA B CB 1 ATOM 7746 N N . GLY B 1 224 ? 63.613 83.695 59.324 1.00 24.64 ? 260 GLY B N 1 ATOM 7747 C CA . GLY B 1 224 ? 63.310 84.866 58.523 1.00 28.16 ? 260 GLY B CA 1 ATOM 7748 C C . GLY B 1 224 ? 61.837 85.135 58.270 1.00 30.05 ? 260 GLY B C 1 ATOM 7749 O O . GLY B 1 224 ? 61.498 86.223 57.818 1.00 32.70 ? 260 GLY B O 1 ATOM 7750 N N . ALA B 1 225 ? 60.960 84.164 58.536 1.00 27.32 ? 261 ALA B N 1 ATOM 7751 C CA . ALA B 1 225 ? 59.523 84.338 58.263 1.00 31.26 ? 261 ALA B CA 1 ATOM 7752 C C . ALA B 1 225 ? 58.828 85.165 59.341 1.00 31.13 ? 261 ALA B C 1 ATOM 7753 O O . ALA B 1 225 ? 59.444 85.543 60.330 1.00 31.14 ? 261 ALA B O 1 ATOM 7754 C CB . ALA B 1 225 ? 58.827 82.981 58.106 1.00 28.75 ? 261 ALA B CB 1 ATOM 7755 N N . VAL B 1 226 ? 57.544 85.453 59.150 1.00 30.55 ? 262 VAL B N 1 ATOM 7756 C CA . VAL B 1 226 ? 56.785 86.210 60.154 1.00 31.88 ? 262 VAL B CA 1 ATOM 7757 C C . VAL B 1 226 ? 56.573 85.421 61.456 1.00 34.15 ? 262 VAL B C 1 ATOM 7758 O O . VAL B 1 226 ? 56.045 84.314 61.427 1.00 28.35 ? 262 VAL B O 1 ATOM 7759 C CB . VAL B 1 226 ? 55.394 86.626 59.638 1.00 32.49 ? 262 VAL B CB 1 ATOM 7760 C CG1 . VAL B 1 226 ? 54.597 87.239 60.756 1.00 32.50 ? 262 VAL B CG1 1 ATOM 7761 C CG2 . VAL B 1 226 ? 55.515 87.602 58.468 1.00 34.38 ? 262 VAL B CG2 1 ATOM 7762 N N . ASN B 1 227 ? 56.980 86.010 62.581 1.00 27.75 ? 263 ASN B N 1 ATOM 7763 C CA . ASN B 1 227 ? 56.831 85.421 63.911 1.00 29.15 ? 263 ASN B CA 1 ATOM 7764 C C . ASN B 1 227 ? 55.501 85.792 64.542 1.00 29.72 ? 263 ASN B C 1 ATOM 7765 O O . ASN B 1 227 ? 54.888 86.799 64.169 1.00 29.32 ? 263 ASN B O 1 ATOM 7766 C CB . ASN B 1 227 ? 57.949 85.917 64.846 1.00 26.03 ? 263 ASN B CB 1 ATOM 7767 C CG . ASN B 1 227 ? 59.189 85.054 64.782 1.00 31.94 ? 263 ASN B CG 1 ATOM 7768 O OD1 . ASN B 1 227 ? 59.159 83.957 64.222 1.00 29.50 ? 263 ASN B OD1 1 ATOM 7769 N ND2 . ASN B 1 227 ? 60.295 85.539 65.365 1.00 27.95 ? 263 ASN B ND2 1 ATOM 7770 N N . PRO B 1 228 ? 55.053 84.994 65.520 1.00 29.45 ? 264 PRO B N 1 ATOM 7771 C CA . PRO B 1 228 ? 53.862 85.378 66.278 1.00 28.00 ? 264 PRO B CA 1 ATOM 7772 C C . PRO B 1 228 ? 54.143 86.670 67.045 1.00 26.46 ? 264 PRO B C 1 ATOM 7773 O O . PRO B 1 228 ? 55.299 86.969 67.325 1.00 27.34 ? 264 PRO B O 1 ATOM 7774 C CB . PRO B 1 228 ? 53.692 84.215 67.262 1.00 26.32 ? 264 PRO B CB 1 ATOM 7775 C CG . PRO B 1 228 ? 55.056 83.672 67.430 1.00 27.76 ? 264 PRO B CG 1 ATOM 7776 C CD . PRO B 1 228 ? 55.684 83.783 66.072 1.00 28.60 ? 264 PRO B CD 1 ATOM 7777 N N . THR B 1 229 ? 53.107 87.440 67.344 1.00 27.04 ? 265 THR B N 1 ATOM 7778 C CA . THR B 1 229 ? 53.262 88.594 68.217 1.00 28.96 ? 265 THR B CA 1 ATOM 7779 C C . THR B 1 229 ? 52.710 88.212 69.583 1.00 30.47 ? 265 THR B C 1 ATOM 7780 O O . THR B 1 229 ? 51.935 87.253 69.691 1.00 26.91 ? 265 THR B O 1 ATOM 7781 C CB . THR B 1 229 ? 52.512 89.828 67.675 1.00 31.21 ? 265 THR B CB 1 ATOM 7782 O OG1 . THR B 1 229 ? 51.105 89.567 67.674 1.00 31.52 ? 265 THR B OG1 1 ATOM 7783 C CG2 . THR B 1 229 ? 52.970 90.159 66.242 1.00 29.93 ? 265 THR B CG2 1 ATOM 7784 N N . VAL B 1 230 ? 53.098 88.965 70.617 1.00 32.08 ? 266 VAL B N 1 ATOM 7785 C CA . VAL B 1 230 ? 52.721 88.637 71.984 1.00 28.14 ? 266 VAL B CA 1 ATOM 7786 C C . VAL B 1 230 ? 52.232 89.857 72.745 1.00 29.93 ? 266 VAL B C 1 ATOM 7787 O O . VAL B 1 230 ? 52.729 90.965 72.537 1.00 29.07 ? 266 VAL B O 1 ATOM 7788 C CB . VAL B 1 230 ? 53.909 88.009 72.743 1.00 27.56 ? 266 VAL B CB 1 ATOM 7789 C CG1 . VAL B 1 230 ? 55.100 88.954 72.743 1.00 28.83 ? 266 VAL B CG1 1 ATOM 7790 C CG2 . VAL B 1 230 ? 53.507 87.645 74.167 1.00 29.41 ? 266 VAL B CG2 1 ATOM 7791 N N . LYS B 1 231 ? 51.247 89.644 73.613 1.00 30.34 ? 267 LYS B N 1 ATOM 7792 C CA . LYS B 1 231 ? 50.806 90.663 74.581 1.00 29.15 ? 267 LYS B CA 1 ATOM 7793 C C . LYS B 1 231 ? 50.830 90.080 75.987 1.00 30.30 ? 267 LYS B C 1 ATOM 7794 O O . LYS B 1 231 ? 50.668 88.872 76.157 1.00 29.98 ? 267 LYS B O 1 ATOM 7795 C CB . LYS B 1 231 ? 49.391 91.141 74.271 1.00 26.87 ? 267 LYS B CB 1 ATOM 7796 C CG . LYS B 1 231 ? 49.266 92.061 73.061 1.00 32.89 ? 267 LYS B CG 1 ATOM 7797 C CD . LYS B 1 231 ? 47.804 92.250 72.683 1.00 36.65 ? 267 LYS B CD 1 ATOM 7798 C CE . LYS B 1 231 ? 47.644 93.197 71.497 1.00 42.41 ? 267 LYS B CE 1 ATOM 7799 N NZ . LYS B 1 231 ? 46.287 93.823 71.503 1.00 38.88 ? 267 LYS B NZ 1 ATOM 7800 N N . PHE B 1 232 ? 50.999 90.933 76.996 1.00 30.45 ? 268 PHE B N 1 ATOM 7801 C CA . PHE B 1 232 ? 50.999 90.467 78.378 1.00 32.78 ? 268 PHE B CA 1 ATOM 7802 C C . PHE B 1 232 ? 49.907 91.165 79.194 1.00 32.94 ? 268 PHE B C 1 ATOM 7803 O O . PHE B 1 232 ? 49.707 92.372 79.056 1.00 34.05 ? 268 PHE B O 1 ATOM 7804 C CB . PHE B 1 232 ? 52.377 90.692 79.011 1.00 33.19 ? 268 PHE B CB 1 ATOM 7805 C CG . PHE B 1 232 ? 52.558 89.991 80.326 1.00 31.83 ? 268 PHE B CG 1 ATOM 7806 C CD1 . PHE B 1 232 ? 52.876 88.644 80.368 1.00 31.62 ? 268 PHE B CD1 1 ATOM 7807 C CD2 . PHE B 1 232 ? 52.421 90.682 81.520 1.00 35.53 ? 268 PHE B CD2 1 ATOM 7808 C CE1 . PHE B 1 232 ? 53.040 87.988 81.591 1.00 32.73 ? 268 PHE B CE1 1 ATOM 7809 C CE2 . PHE B 1 232 ? 52.588 90.038 82.742 1.00 35.59 ? 268 PHE B CE2 1 ATOM 7810 C CZ . PHE B 1 232 ? 52.896 88.692 82.775 1.00 33.43 ? 268 PHE B CZ 1 ATOM 7811 N N . PHE B 1 233 ? 49.203 90.399 80.027 1.00 29.23 ? 269 PHE B N 1 ATOM 7812 C CA . PHE B 1 233 ? 48.058 90.888 80.791 1.00 32.75 ? 269 PHE B CA 1 ATOM 7813 C C . PHE B 1 233 ? 48.093 90.393 82.231 1.00 35.13 ? 269 PHE B C 1 ATOM 7814 O O . PHE B 1 233 ? 48.631 89.324 82.507 1.00 35.72 ? 269 PHE B O 1 ATOM 7815 C CB . PHE B 1 233 ? 46.749 90.391 80.171 1.00 33.84 ? 269 PHE B CB 1 ATOM 7816 C CG . PHE B 1 233 ? 46.505 90.872 78.776 1.00 37.21 ? 269 PHE B CG 1 ATOM 7817 C CD1 . PHE B 1 233 ? 46.005 92.147 78.544 1.00 38.37 ? 269 PHE B CD1 1 ATOM 7818 C CD2 . PHE B 1 233 ? 46.741 90.044 77.692 1.00 35.30 ? 269 PHE B CD2 1 ATOM 7819 C CE1 . PHE B 1 233 ? 45.767 92.593 77.265 1.00 35.64 ? 269 PHE B CE1 1 ATOM 7820 C CE2 . PHE B 1 233 ? 46.501 90.489 76.401 1.00 36.03 ? 269 PHE B CE2 1 ATOM 7821 C CZ . PHE B 1 233 ? 46.016 91.764 76.190 1.00 38.82 ? 269 PHE B CZ 1 ATOM 7822 N N . VAL B 1 234 ? 47.496 91.156 83.145 1.00 35.08 ? 270 VAL B N 1 ATOM 7823 C CA . VAL B 1 234 ? 47.359 90.737 84.543 1.00 32.70 ? 270 VAL B CA 1 ATOM 7824 C C . VAL B 1 234 ? 45.923 90.967 85.029 1.00 39.18 ? 270 VAL B C 1 ATOM 7825 O O . VAL B 1 234 ? 45.389 92.077 84.906 1.00 36.27 ? 270 VAL B O 1 ATOM 7826 C CB . VAL B 1 234 ? 48.324 91.497 85.472 1.00 32.73 ? 270 VAL B CB 1 ATOM 7827 C CG1 . VAL B 1 234 ? 48.166 91.015 86.921 1.00 34.44 ? 270 VAL B CG1 1 ATOM 7828 C CG2 . VAL B 1 234 ? 49.748 91.317 85.010 1.00 33.58 ? 270 VAL B CG2 1 ATOM 7829 N N . VAL B 1 235 ? 45.298 89.917 85.565 1.00 33.10 ? 271 VAL B N 1 ATOM 7830 C CA . VAL B 1 235 ? 43.920 89.997 86.037 1.00 35.97 ? 271 VAL B CA 1 ATOM 7831 C C . VAL B 1 235 ? 43.842 89.831 87.553 1.00 38.44 ? 271 VAL B C 1 ATOM 7832 O O . VAL B 1 235 ? 44.498 88.961 88.120 1.00 39.29 ? 271 VAL B O 1 ATOM 7833 C CB . VAL B 1 235 ? 43.047 88.897 85.405 1.00 40.67 ? 271 VAL B CB 1 ATOM 7834 C CG1 . VAL B 1 235 ? 41.582 89.144 85.708 1.00 40.61 ? 271 VAL B CG1 1 ATOM 7835 C CG2 . VAL B 1 235 ? 43.272 88.831 83.908 1.00 45.97 ? 271 VAL B CG2 1 ATOM 7836 N N . ASN B 1 236 ? 43.035 90.660 88.210 1.00 42.25 ? 272 ASN B N 1 ATOM 7837 C CA . ASN B 1 236 ? 42.814 90.530 89.649 1.00 39.40 ? 272 ASN B CA 1 ATOM 7838 C C . ASN B 1 236 ? 41.737 89.491 89.939 1.00 41.04 ? 272 ASN B C 1 ATOM 7839 O O . ASN B 1 236 ? 40.555 89.695 89.648 1.00 44.43 ? 272 ASN B O 1 ATOM 7840 C CB . ASN B 1 236 ? 42.445 91.884 90.265 1.00 45.15 ? 272 ASN B CB 1 ATOM 7841 C CG . ASN B 1 236 ? 42.543 91.882 91.778 1.00 47.32 ? 272 ASN B CG 1 ATOM 7842 O OD1 . ASN B 1 236 ? 42.193 90.897 92.429 1.00 43.10 ? 272 ASN B OD1 1 ATOM 7843 N ND2 . ASN B 1 236 ? 43.032 92.982 92.345 1.00 45.04 ? 272 ASN B ND2 1 ATOM 7844 N N . THR B 1 237 ? 42.152 88.375 90.520 1.00 40.10 ? 273 THR B N 1 ATOM 7845 C CA . THR B 1 237 ? 41.287 87.210 90.645 1.00 39.85 ? 273 THR B CA 1 ATOM 7846 C C . THR B 1 237 ? 40.335 87.282 91.863 1.00 45.46 ? 273 THR B C 1 ATOM 7847 O O . THR B 1 237 ? 39.381 86.506 91.974 1.00 43.12 ? 273 THR B O 1 ATOM 7848 C CB . THR B 1 237 ? 42.147 85.926 90.640 1.00 44.83 ? 273 THR B CB 1 ATOM 7849 O OG1 . THR B 1 237 ? 41.511 84.911 89.858 1.00 52.44 ? 273 THR B OG1 1 ATOM 7850 C CG2 . THR B 1 237 ? 42.404 85.420 92.032 1.00 39.05 ? 273 THR B CG2 1 ATOM 7851 N N . ASP B 1 238 ? 40.587 88.241 92.750 1.00 46.11 ? 274 ASP B N 1 ATOM 7852 C CA . ASP B 1 238 ? 39.738 88.481 93.920 1.00 49.12 ? 274 ASP B CA 1 ATOM 7853 C C . ASP B 1 238 ? 38.458 89.258 93.580 1.00 50.59 ? 274 ASP B C 1 ATOM 7854 O O . ASP B 1 238 ? 37.442 89.125 94.262 1.00 55.63 ? 274 ASP B O 1 ATOM 7855 C CB . ASP B 1 238 ? 40.530 89.222 95.005 1.00 45.41 ? 274 ASP B CB 1 ATOM 7856 C CG . ASP B 1 238 ? 41.581 88.342 95.671 1.00 49.69 ? 274 ASP B CG 1 ATOM 7857 O OD1 . ASP B 1 238 ? 41.460 87.102 95.580 1.00 49.34 ? 274 ASP B OD1 1 ATOM 7858 O OD2 . ASP B 1 238 ? 42.521 88.884 96.301 1.00 55.30 ? 274 ASP B OD2 1 ATOM 7859 N N . SER B 1 239 ? 38.507 90.059 92.519 1.00 53.53 ? 275 SER B N 1 ATOM 7860 C CA . SER B 1 239 ? 37.384 90.932 92.161 1.00 57.70 ? 275 SER B CA 1 ATOM 7861 C C . SER B 1 239 ? 36.512 90.397 91.020 1.00 60.52 ? 275 SER B C 1 ATOM 7862 O O . SER B 1 239 ? 35.856 91.171 90.317 1.00 59.67 ? 275 SER B O 1 ATOM 7863 C CB . SER B 1 239 ? 37.891 92.342 91.811 1.00 57.73 ? 275 SER B CB 1 ATOM 7864 O OG . SER B 1 239 ? 38.658 92.344 90.618 1.00 53.04 ? 275 SER B OG 1 ATOM 7865 N N . LEU B 1 240 ? 36.495 89.079 90.841 1.00 59.05 ? 276 LEU B N 1 ATOM 7866 C CA . LEU B 1 240 ? 35.762 88.478 89.730 1.00 57.75 ? 276 LEU B CA 1 ATOM 7867 C C . LEU B 1 240 ? 34.247 88.557 89.914 1.00 62.62 ? 276 LEU B C 1 ATOM 7868 O O . LEU B 1 240 ? 33.708 88.120 90.929 1.00 59.75 ? 276 LEU B O 1 ATOM 7869 C CB . LEU B 1 240 ? 36.214 87.034 89.496 1.00 54.54 ? 276 LEU B CB 1 ATOM 7870 C CG . LEU B 1 240 ? 37.622 86.919 88.908 1.00 46.42 ? 276 LEU B CG 1 ATOM 7871 C CD1 . LEU B 1 240 ? 37.961 85.474 88.601 1.00 40.56 ? 276 LEU B CD1 1 ATOM 7872 C CD2 . LEU B 1 240 ? 37.714 87.763 87.656 1.00 42.48 ? 276 LEU B CD2 1 ATOM 7873 N N . SER B 1 241 ? 33.572 89.116 88.913 1.00 67.39 ? 277 SER B N 1 ATOM 7874 C CA . SER B 1 241 ? 32.129 89.326 88.968 1.00 71.70 ? 277 SER B CA 1 ATOM 7875 C C . SER B 1 241 ? 31.368 88.316 88.118 1.00 70.61 ? 277 SER B C 1 ATOM 7876 O O . SER B 1 241 ? 31.761 88.013 86.989 1.00 70.16 ? 277 SER B O 1 ATOM 7877 C CB . SER B 1 241 ? 31.778 90.749 88.518 1.00 74.74 ? 277 SER B CB 1 ATOM 7878 O OG . SER B 1 241 ? 30.375 90.907 88.362 1.00 77.80 ? 277 SER B OG 1 ATOM 7879 N N . SER B 1 242 ? 30.271 87.803 88.664 1.00 70.07 ? 278 SER B N 1 ATOM 7880 C CA . SER B 1 242 ? 29.418 86.881 87.926 1.00 72.04 ? 278 SER B CA 1 ATOM 7881 C C . SER B 1 242 ? 28.611 87.619 86.855 1.00 79.65 ? 278 SER B C 1 ATOM 7882 O O . SER B 1 242 ? 28.030 86.993 85.961 1.00 79.89 ? 278 SER B O 1 ATOM 7883 C CB . SER B 1 242 ? 28.479 86.140 88.882 1.00 68.75 ? 278 SER B CB 1 ATOM 7884 N N . VAL B 1 243 ? 28.587 88.949 86.940 1.00 77.30 ? 279 VAL B N 1 ATOM 7885 C CA . VAL B 1 243 ? 27.754 89.759 86.050 1.00 78.65 ? 279 VAL B CA 1 ATOM 7886 C C . VAL B 1 243 ? 28.552 90.456 84.950 1.00 78.51 ? 279 VAL B C 1 ATOM 7887 O O . VAL B 1 243 ? 28.101 90.535 83.806 1.00 74.62 ? 279 VAL B O 1 ATOM 7888 C CB . VAL B 1 243 ? 26.955 90.821 86.835 1.00 76.31 ? 279 VAL B CB 1 ATOM 7889 N N . THR B 1 244 ? 29.733 90.958 85.303 1.00 78.56 ? 280 THR B N 1 ATOM 7890 C CA . THR B 1 244 ? 30.591 91.668 84.354 1.00 76.67 ? 280 THR B CA 1 ATOM 7891 C C . THR B 1 244 ? 31.808 90.836 83.934 1.00 74.29 ? 280 THR B C 1 ATOM 7892 O O . THR B 1 244 ? 32.446 90.177 84.762 1.00 72.17 ? 280 THR B O 1 ATOM 7893 C CB . THR B 1 244 ? 31.093 93.008 84.942 1.00 76.96 ? 280 THR B CB 1 ATOM 7894 O OG1 . THR B 1 244 ? 30.009 93.686 85.591 1.00 80.57 ? 280 THR B OG1 1 ATOM 7895 C CG2 . THR B 1 244 ? 31.678 93.902 83.846 1.00 73.15 ? 280 THR B CG2 1 ATOM 7896 N N . ASN B 1 245 ? 32.121 90.867 82.642 1.00 70.52 ? 281 ASN B N 1 ATOM 7897 C CA . ASN B 1 245 ? 33.343 90.254 82.147 1.00 68.08 ? 281 ASN B CA 1 ATOM 7898 C C . ASN B 1 245 ? 34.513 90.751 82.994 1.00 67.42 ? 281 ASN B C 1 ATOM 7899 O O . ASN B 1 245 ? 34.523 91.908 83.421 1.00 65.32 ? 281 ASN B O 1 ATOM 7900 C CB . ASN B 1 245 ? 33.566 90.599 80.664 1.00 61.78 ? 281 ASN B CB 1 ATOM 7901 C CG . ASN B 1 245 ? 32.466 90.051 79.757 1.00 66.27 ? 281 ASN B CG 1 ATOM 7902 O OD1 . ASN B 1 245 ? 31.724 89.140 80.140 1.00 67.37 ? 281 ASN B OD1 1 ATOM 7903 N ND2 . ASN B 1 245 ? 32.364 90.601 78.542 1.00 60.20 ? 281 ASN B ND2 1 ATOM 7904 N N . ALA B 1 246 ? 35.483 89.879 83.257 1.00 63.38 ? 282 ALA B N 1 ATOM 7905 C CA . ALA B 1 246 ? 36.668 90.278 84.010 1.00 58.10 ? 282 ALA B CA 1 ATOM 7906 C C . ALA B 1 246 ? 37.489 91.279 83.206 1.00 58.08 ? 282 ALA B C 1 ATOM 7907 O O . ALA B 1 246 ? 37.433 91.291 81.971 1.00 56.18 ? 282 ALA B O 1 ATOM 7908 C CB . ALA B 1 246 ? 37.508 89.069 84.360 1.00 52.08 ? 282 ALA B CB 1 ATOM 7909 N N . THR B 1 247 ? 38.259 92.107 83.909 1.00 52.35 ? 283 THR B N 1 ATOM 7910 C CA . THR B 1 247 ? 39.063 93.136 83.260 1.00 50.36 ? 283 THR B CA 1 ATOM 7911 C C . THR B 1 247 ? 40.561 92.873 83.369 1.00 49.15 ? 283 THR B C 1 ATOM 7912 O O . THR B 1 247 ? 41.124 92.918 84.463 1.00 51.91 ? 283 THR B O 1 ATOM 7913 C CB . THR B 1 247 ? 38.776 94.531 83.851 1.00 57.62 ? 283 THR B CB 1 ATOM 7914 O OG1 . THR B 1 247 ? 37.476 94.973 83.437 1.00 59.14 ? 283 THR B OG1 1 ATOM 7915 C CG2 . THR B 1 247 ? 39.824 95.530 83.371 1.00 56.16 ? 283 THR B CG2 1 ATOM 7916 N N . SER B 1 248 ? 41.205 92.620 82.234 1.00 42.27 ? 284 SER B N 1 ATOM 7917 C CA . SER B 1 248 ? 42.645 92.392 82.207 1.00 40.92 ? 284 SER B CA 1 ATOM 7918 C C . SER B 1 248 ? 43.386 93.703 81.999 1.00 43.90 ? 284 SER B C 1 ATOM 7919 O O . SER B 1 248 ? 43.005 94.517 81.154 1.00 46.05 ? 284 SER B O 1 ATOM 7920 C CB . SER B 1 248 ? 43.030 91.420 81.086 1.00 41.05 ? 284 SER B CB 1 ATOM 7921 O OG . SER B 1 248 ? 42.242 90.243 81.110 1.00 42.21 ? 284 SER B OG 1 ATOM 7922 N N . ILE B 1 249 ? 44.458 93.898 82.754 1.00 38.19 ? 285 ILE B N 1 ATOM 7923 C CA . ILE B 1 249 ? 45.297 95.068 82.571 1.00 42.59 ? 285 ILE B CA 1 ATOM 7924 C C . ILE B 1 249 ? 46.493 94.680 81.732 1.00 39.85 ? 285 ILE B C 1 ATOM 7925 O O . ILE B 1 249 ? 47.230 93.778 82.108 1.00 38.26 ? 285 ILE B O 1 ATOM 7926 C CB . ILE B 1 249 ? 45.805 95.597 83.912 1.00 37.70 ? 285 ILE B CB 1 ATOM 7927 C CG1 . ILE B 1 249 ? 44.625 95.826 84.855 1.00 41.49 ? 285 ILE B CG1 1 ATOM 7928 C CG2 . ILE B 1 249 ? 46.619 96.867 83.711 1.00 41.26 ? 285 ILE B CG2 1 ATOM 7929 C CD1 . ILE B 1 249 ? 43.517 96.649 84.243 1.00 50.11 ? 285 ILE B CD1 1 ATOM 7930 N N . GLN B 1 250 ? 46.680 95.342 80.593 1.00 39.60 ? 286 GLN B N 1 ATOM 7931 C CA . GLN B 1 250 ? 47.810 95.023 79.725 1.00 34.91 ? 286 GLN B CA 1 ATOM 7932 C C . GLN B 1 250 ? 49.067 95.684 80.235 1.00 35.32 ? 286 GLN B C 1 ATOM 7933 O O . GLN B 1 250 ? 49.035 96.806 80.728 1.00 40.42 ? 286 GLN B O 1 ATOM 7934 C CB . GLN B 1 250 ? 47.553 95.472 78.287 1.00 37.19 ? 286 GLN B CB 1 ATOM 7935 C CG . GLN B 1 250 ? 48.729 95.216 77.340 1.00 36.16 ? 286 GLN B CG 1 ATOM 7936 C CD . GLN B 1 250 ? 48.362 95.402 75.868 1.00 37.63 ? 286 GLN B CD 1 ATOM 7937 O OE1 . GLN B 1 250 ? 47.266 95.855 75.541 1.00 38.08 ? 286 GLN B OE1 1 ATOM 7938 N NE2 . GLN B 1 250 ? 49.280 95.045 74.979 1.00 33.72 ? 286 GLN B NE2 1 ATOM 7939 N N . ILE B 1 251 ? 50.181 94.979 80.132 1.00 37.58 ? 287 ILE B N 1 ATOM 7940 C CA . ILE B 1 251 ? 51.474 95.574 80.401 1.00 31.82 ? 287 ILE B CA 1 ATOM 7941 C C . ILE B 1 251 ? 52.198 95.589 79.078 1.00 40.04 ? 287 ILE B C 1 ATOM 7942 O O . ILE B 1 251 ? 52.375 94.547 78.441 1.00 36.12 ? 287 ILE B O 1 ATOM 7943 C CB . ILE B 1 251 ? 52.266 94.783 81.457 1.00 36.58 ? 287 ILE B CB 1 ATOM 7944 C CG1 . ILE B 1 251 ? 51.541 94.827 82.801 1.00 37.00 ? 287 ILE B CG1 1 ATOM 7945 C CG2 . ILE B 1 251 ? 53.668 95.340 81.606 1.00 39.15 ? 287 ILE B CG2 1 ATOM 7946 C CD1 . ILE B 1 251 ? 52.265 94.088 83.922 1.00 37.17 ? 287 ILE B CD1 1 ATOM 7947 N N . THR B 1 252 ? 52.587 96.787 78.654 1.00 39.67 ? 288 THR B N 1 ATOM 7948 C CA . THR B 1 252 ? 53.223 96.994 77.363 1.00 41.75 ? 288 THR B CA 1 ATOM 7949 C C . THR B 1 252 ? 54.724 96.722 77.433 1.00 39.34 ? 288 THR B C 1 ATOM 7950 O O . THR B 1 252 ? 55.349 96.959 78.460 1.00 38.91 ? 288 THR B O 1 ATOM 7951 C CB . THR B 1 252 ? 52.954 98.434 76.882 1.00 42.71 ? 288 THR B CB 1 ATOM 7952 O OG1 . THR B 1 252 ? 51.550 98.581 76.615 1.00 44.45 ? 288 THR B OG1 1 ATOM 7953 C CG2 . THR B 1 252 ? 53.734 98.740 75.619 1.00 46.14 ? 288 THR B CG2 1 ATOM 7954 N N . ALA B 1 253 ? 55.294 96.194 76.352 1.00 36.76 ? 289 ALA B N 1 ATOM 7955 C CA . ALA B 1 253 ? 56.737 96.007 76.280 1.00 38.66 ? 289 ALA B CA 1 ATOM 7956 C C . ALA B 1 253 ? 57.398 97.382 76.250 1.00 38.42 ? 289 ALA B C 1 ATOM 7957 O O . ALA B 1 253 ? 56.764 98.366 75.890 1.00 39.82 ? 289 ALA B O 1 ATOM 7958 C CB . ALA B 1 253 ? 57.116 95.197 75.027 1.00 36.45 ? 289 ALA B CB 1 ATOM 7959 N N . PRO B 1 254 ? 58.674 97.455 76.632 1.00 38.36 ? 290 PRO B N 1 ATOM 7960 C CA . PRO B 1 254 ? 59.415 98.722 76.595 1.00 40.41 ? 290 PRO B CA 1 ATOM 7961 C C . PRO B 1 254 ? 59.460 99.280 75.174 1.00 42.81 ? 290 PRO B C 1 ATOM 7962 O O . PRO B 1 254 ? 59.362 98.501 74.229 1.00 42.14 ? 290 PRO B O 1 ATOM 7963 C CB . PRO B 1 254 ? 60.823 98.308 77.029 1.00 36.06 ? 290 PRO B CB 1 ATOM 7964 C CG . PRO B 1 254 ? 60.631 97.047 77.800 1.00 35.51 ? 290 PRO B CG 1 ATOM 7965 C CD . PRO B 1 254 ? 59.487 96.346 77.157 1.00 37.75 ? 290 PRO B CD 1 ATOM 7966 N N . ALA B 1 255 ? 59.616 100.592 75.016 1.00 41.07 ? 291 ALA B N 1 ATOM 7967 C CA . ALA B 1 255 ? 59.717 101.185 73.678 1.00 42.18 ? 291 ALA B CA 1 ATOM 7968 C C . ALA B 1 255 ? 60.895 100.624 72.882 1.00 43.08 ? 291 ALA B C 1 ATOM 7969 O O . ALA B 1 255 ? 60.825 100.512 71.652 1.00 40.29 ? 291 ALA B O 1 ATOM 7970 C CB . ALA B 1 255 ? 59.811 102.705 73.764 1.00 45.14 ? 291 ALA B CB 1 ATOM 7971 N N . SER B 1 256 ? 61.972 100.263 73.579 1.00 36.16 ? 292 SER B N 1 ATOM 7972 C CA . SER B 1 256 ? 63.165 99.738 72.915 1.00 38.56 ? 292 SER B CA 1 ATOM 7973 C C . SER B 1 256 ? 62.922 98.367 72.253 1.00 38.55 ? 292 SER B C 1 ATOM 7974 O O . SER B 1 256 ? 63.712 97.930 71.416 1.00 39.95 ? 292 SER B O 1 ATOM 7975 C CB . SER B 1 256 ? 64.325 99.637 73.902 1.00 37.89 ? 292 SER B CB 1 ATOM 7976 O OG . SER B 1 256 ? 64.083 98.593 74.828 1.00 38.37 ? 292 SER B OG 1 ATOM 7977 N N . MET B 1 257 ? 61.836 97.704 72.649 1.00 38.09 ? 293 MET B N 1 ATOM 7978 C CA . MET B 1 257 ? 61.373 96.466 72.023 1.00 38.42 ? 293 MET B CA 1 ATOM 7979 C C . MET B 1 257 ? 60.297 96.737 70.972 1.00 37.41 ? 293 MET B C 1 ATOM 7980 O O . MET B 1 257 ? 60.289 96.118 69.914 1.00 34.46 ? 293 MET B O 1 ATOM 7981 C CB . MET B 1 257 ? 60.805 95.515 73.076 1.00 33.90 ? 293 MET B CB 1 ATOM 7982 C CG . MET B 1 257 ? 61.847 94.996 74.046 1.00 36.48 ? 293 MET B CG 1 ATOM 7983 S SD . MET B 1 257 ? 62.922 93.794 73.246 1.00 35.31 ? 293 MET B SD 1 ATOM 7984 C CE . MET B 1 257 ? 64.426 94.018 74.201 1.00 31.99 ? 293 MET B CE 1 ATOM 7985 N N . LEU B 1 258 ? 59.388 97.660 71.274 1.00 37.30 ? 294 LEU B N 1 ATOM 7986 C CA . LEU B 1 258 ? 58.271 97.972 70.378 1.00 38.58 ? 294 LEU B CA 1 ATOM 7987 C C . LEU B 1 258 ? 58.689 98.505 68.999 1.00 38.61 ? 294 LEU B C 1 ATOM 7988 O O . LEU B 1 258 ? 57.868 98.565 68.082 1.00 41.53 ? 294 LEU B O 1 ATOM 7989 C CB . LEU B 1 258 ? 57.313 98.973 71.035 1.00 40.98 ? 294 LEU B CB 1 ATOM 7990 C CG . LEU B 1 258 ? 56.561 98.624 72.320 1.00 43.06 ? 294 LEU B CG 1 ATOM 7991 C CD1 . LEU B 1 258 ? 55.662 99.801 72.716 1.00 40.64 ? 294 LEU B CD1 1 ATOM 7992 C CD2 . LEU B 1 258 ? 55.738 97.359 72.171 1.00 41.44 ? 294 LEU B CD2 1 ATOM 7993 N N . ILE B 1 259 ? 59.955 98.891 68.847 1.00 37.25 ? 295 ILE B N 1 ATOM 7994 C CA . ILE B 1 259 ? 60.438 99.404 67.563 1.00 40.56 ? 295 ILE B CA 1 ATOM 7995 C C . ILE B 1 259 ? 60.557 98.317 66.490 1.00 44.27 ? 295 ILE B C 1 ATOM 7996 O O . ILE B 1 259 ? 60.732 98.627 65.316 1.00 39.50 ? 295 ILE B O 1 ATOM 7997 C CB . ILE B 1 259 ? 61.808 100.096 67.689 1.00 37.10 ? 295 ILE B CB 1 ATOM 7998 C CG1 . ILE B 1 259 ? 62.865 99.100 68.172 1.00 42.69 ? 295 ILE B CG1 1 ATOM 7999 C CG2 . ILE B 1 259 ? 61.720 101.301 68.613 1.00 44.43 ? 295 ILE B CG2 1 ATOM 8000 C CD1 . ILE B 1 259 ? 64.291 99.540 67.901 1.00 45.84 ? 295 ILE B CD1 1 ATOM 8001 N N . GLY B 1 260 ? 60.478 97.048 66.885 1.00 38.61 ? 296 GLY B N 1 ATOM 8002 C CA . GLY B 1 260 ? 60.617 95.962 65.923 1.00 35.62 ? 296 GLY B CA 1 ATOM 8003 C C . GLY B 1 260 ? 60.130 94.631 66.465 1.00 38.62 ? 296 GLY B C 1 ATOM 8004 O O . GLY B 1 260 ? 59.425 94.591 67.468 1.00 37.74 ? 296 GLY B O 1 ATOM 8005 N N . ASP B 1 261 ? 60.493 93.539 65.798 1.00 36.35 ? 297 ASP B N 1 ATOM 8006 C CA . ASP B 1 261 ? 60.104 92.223 66.273 1.00 33.71 ? 297 ASP B CA 1 ATOM 8007 C C . ASP B 1 261 ? 60.820 91.903 67.577 1.00 31.69 ? 297 ASP B C 1 ATOM 8008 O O . ASP B 1 261 ? 62.006 92.207 67.748 1.00 28.82 ? 297 ASP B O 1 ATOM 8009 C CB . ASP B 1 261 ? 60.393 91.140 65.228 1.00 35.96 ? 297 ASP B CB 1 ATOM 8010 C CG . ASP B 1 261 ? 59.408 91.161 64.065 1.00 41.08 ? 297 ASP B CG 1 ATOM 8011 O OD1 . ASP B 1 261 ? 58.388 91.877 64.146 1.00 43.16 ? 297 ASP B OD1 1 ATOM 8012 O OD2 . ASP B 1 261 ? 59.649 90.434 63.074 1.00 42.24 ? 297 ASP B OD2 1 ATOM 8013 N N . HIS B 1 262 ? 60.097 91.268 68.491 1.00 30.10 ? 298 HIS B N 1 ATOM 8014 C CA . HIS B 1 262 ? 60.633 90.963 69.810 1.00 27.07 ? 298 HIS B CA 1 ATOM 8015 C C . HIS B 1 262 ? 59.916 89.754 70.408 1.00 30.28 ? 298 HIS B C 1 ATOM 8016 O O . HIS B 1 262 ? 58.945 89.251 69.841 1.00 30.66 ? 298 HIS B O 1 ATOM 8017 C CB . HIS B 1 262 ? 60.457 92.165 70.748 1.00 28.25 ? 298 HIS B CB 1 ATOM 8018 C CG . HIS B 1 262 ? 59.031 92.611 70.898 1.00 31.92 ? 298 HIS B CG 1 ATOM 8019 N ND1 . HIS B 1 262 ? 58.426 93.486 70.018 1.00 30.69 ? 298 HIS B ND1 1 ATOM 8020 C CD2 . HIS B 1 262 ? 58.090 92.299 71.821 1.00 28.48 ? 298 HIS B CD2 1 ATOM 8021 C CE1 . HIS B 1 262 ? 57.176 93.690 70.392 1.00 30.69 ? 298 HIS B CE1 1 ATOM 8022 N NE2 . HIS B 1 262 ? 56.945 92.981 71.483 1.00 29.93 ? 298 HIS B NE2 1 ATOM 8023 N N . TYR B 1 263 ? 60.394 89.318 71.569 1.00 29.54 ? 299 TYR B N 1 ATOM 8024 C CA . TYR B 1 263 ? 59.827 88.181 72.282 1.00 29.80 ? 299 TYR B CA 1 ATOM 8025 C C . TYR B 1 263 ? 59.661 88.525 73.753 1.00 28.79 ? 299 TYR B C 1 ATOM 8026 O O . TYR B 1 263 ? 60.415 89.325 74.301 1.00 28.87 ? 299 TYR B O 1 ATOM 8027 C CB . TYR B 1 263 ? 60.783 86.992 72.241 1.00 25.89 ? 299 TYR B CB 1 ATOM 8028 C CG . TYR B 1 263 ? 61.234 86.535 70.880 1.00 28.66 ? 299 TYR B CG 1 ATOM 8029 C CD1 . TYR B 1 263 ? 60.376 85.849 70.035 1.00 28.78 ? 299 TYR B CD1 1 ATOM 8030 C CD2 . TYR B 1 263 ? 62.538 86.735 70.465 1.00 30.24 ? 299 TYR B CD2 1 ATOM 8031 C CE1 . TYR B 1 263 ? 60.802 85.407 68.780 1.00 27.98 ? 299 TYR B CE1 1 ATOM 8032 C CE2 . TYR B 1 263 ? 62.974 86.294 69.215 1.00 27.34 ? 299 TYR B CE2 1 ATOM 8033 C CZ . TYR B 1 263 ? 62.101 85.629 68.390 1.00 27.42 ? 299 TYR B CZ 1 ATOM 8034 O OH . TYR B 1 263 ? 62.544 85.195 67.168 1.00 28.80 ? 299 TYR B OH 1 ATOM 8035 N N . LEU B 1 264 ? 58.690 87.897 74.398 1.00 29.39 ? 300 LEU B N 1 ATOM 8036 C CA . LEU B 1 264 ? 58.635 87.890 75.861 1.00 29.37 ? 300 LEU B CA 1 ATOM 8037 C C . LEU B 1 264 ? 59.336 86.614 76.294 1.00 31.62 ? 300 LEU B C 1 ATOM 8038 O O . LEU B 1 264 ? 58.941 85.529 75.876 1.00 32.57 ? 300 LEU B O 1 ATOM 8039 C CB . LEU B 1 264 ? 57.186 87.863 76.322 1.00 27.92 ? 300 LEU B CB 1 ATOM 8040 C CG . LEU B 1 264 ? 56.972 87.671 77.820 1.00 30.42 ? 300 LEU B CG 1 ATOM 8041 C CD1 . LEU B 1 264 ? 57.357 88.935 78.566 1.00 31.69 ? 300 LEU B CD1 1 ATOM 8042 C CD2 . LEU B 1 264 ? 55.523 87.335 78.033 1.00 35.27 ? 300 LEU B CD2 1 ATOM 8043 N N . CYS B 1 265 ? 60.391 86.708 77.090 1.00 30.90 ? 301 CYS B N 1 ATOM 8044 C CA . CYS B 1 265 ? 61.165 85.499 77.330 1.00 35.56 ? 301 CYS B CA 1 ATOM 8045 C C . CYS B 1 265 ? 61.290 85.038 78.779 1.00 37.30 ? 301 CYS B C 1 ATOM 8046 O O . CYS B 1 265 ? 61.832 83.968 79.020 1.00 42.85 ? 301 CYS B O 1 ATOM 8047 C CB . CYS B 1 265 ? 62.537 85.568 76.644 1.00 37.38 ? 301 CYS B CB 1 ATOM 8048 S SG . CYS B 1 265 ? 63.618 86.852 77.280 1.00 47.46 ? 301 CYS B SG 1 ATOM 8049 N N . ASP B 1 266 ? 60.773 85.816 79.732 1.00 35.69 ? 302 ASP B N 1 ATOM 8050 C CA . ASP B 1 266 ? 60.765 85.408 81.142 1.00 36.30 ? 302 ASP B CA 1 ATOM 8051 C C . ASP B 1 266 ? 59.730 86.214 81.934 1.00 36.49 ? 302 ASP B C 1 ATOM 8052 O O . ASP B 1 266 ? 59.597 87.423 81.741 1.00 34.97 ? 302 ASP B O 1 ATOM 8053 C CB . ASP B 1 266 ? 62.163 85.558 81.765 1.00 36.07 ? 302 ASP B CB 1 ATOM 8054 C CG . ASP B 1 266 ? 62.268 84.911 83.160 1.00 45.11 ? 302 ASP B CG 1 ATOM 8055 O OD1 . ASP B 1 266 ? 62.303 83.656 83.247 1.00 42.68 ? 302 ASP B OD1 1 ATOM 8056 O OD2 . ASP B 1 266 ? 62.316 85.658 84.168 1.00 43.45 ? 302 ASP B OD2 1 ATOM 8057 N N . VAL B 1 267 ? 58.972 85.536 82.791 1.00 27.45 ? 303 VAL B N 1 ATOM 8058 C CA . VAL B 1 267 ? 58.051 86.201 83.701 1.00 27.80 ? 303 VAL B CA 1 ATOM 8059 C C . VAL B 1 267 ? 58.278 85.655 85.105 1.00 36.86 ? 303 VAL B C 1 ATOM 8060 O O . VAL B 1 267 ? 58.155 84.447 85.325 1.00 33.00 ? 303 VAL B O 1 ATOM 8061 C CB . VAL B 1 267 ? 56.576 85.931 83.340 1.00 33.89 ? 303 VAL B CB 1 ATOM 8062 C CG1 . VAL B 1 267 ? 55.657 86.713 84.288 1.00 30.71 ? 303 VAL B CG1 1 ATOM 8063 C CG2 . VAL B 1 267 ? 56.295 86.277 81.871 1.00 33.24 ? 303 VAL B CG2 1 ATOM 8064 N N . THR B 1 268 ? 58.599 86.530 86.053 1.00 30.08 ? 304 THR B N 1 ATOM 8065 C CA . THR B 1 268 ? 58.866 86.090 87.422 1.00 33.28 ? 304 THR B CA 1 ATOM 8066 C C . THR B 1 268 ? 58.232 87.060 88.405 1.00 34.62 ? 304 THR B C 1 ATOM 8067 O O . THR B 1 268 ? 58.575 88.238 88.415 1.00 32.65 ? 304 THR B O 1 ATOM 8068 C CB . THR B 1 268 ? 60.396 86.021 87.716 1.00 33.32 ? 304 THR B CB 1 ATOM 8069 O OG1 . THR B 1 268 ? 61.048 85.180 86.750 1.00 37.90 ? 304 THR B OG1 1 ATOM 8070 C CG2 . THR B 1 268 ? 60.663 85.480 89.110 1.00 33.07 ? 304 THR B CG2 1 ATOM 8071 N N . TRP B 1 269 ? 57.313 86.564 89.229 1.00 31.48 ? 305 TRP B N 1 ATOM 8072 C CA . TRP B 1 269 ? 56.747 87.358 90.314 1.00 32.67 ? 305 TRP B CA 1 ATOM 8073 C C . TRP B 1 269 ? 57.793 87.617 91.393 1.00 33.08 ? 305 TRP B C 1 ATOM 8074 O O . TRP B 1 269 ? 58.462 86.690 91.850 1.00 37.74 ? 305 TRP B O 1 ATOM 8075 C CB . TRP B 1 269 ? 55.535 86.648 90.910 1.00 32.00 ? 305 TRP B CB 1 ATOM 8076 C CG . TRP B 1 269 ? 54.295 86.801 90.090 1.00 32.83 ? 305 TRP B CG 1 ATOM 8077 C CD1 . TRP B 1 269 ? 53.812 85.928 89.140 1.00 30.26 ? 305 TRP B CD1 1 ATOM 8078 C CD2 . TRP B 1 269 ? 53.373 87.895 90.138 1.00 30.60 ? 305 TRP B CD2 1 ATOM 8079 N NE1 . TRP B 1 269 ? 52.639 86.415 88.616 1.00 32.08 ? 305 TRP B NE1 1 ATOM 8080 C CE2 . TRP B 1 269 ? 52.349 87.621 89.208 1.00 32.28 ? 305 TRP B CE2 1 ATOM 8081 C CE3 . TRP B 1 269 ? 53.309 89.079 90.884 1.00 33.27 ? 305 TRP B CE3 1 ATOM 8082 C CZ2 . TRP B 1 269 ? 51.278 88.495 88.996 1.00 30.57 ? 305 TRP B CZ2 1 ATOM 8083 C CZ3 . TRP B 1 269 ? 52.240 89.948 90.668 1.00 32.69 ? 305 TRP B CZ3 1 ATOM 8084 C CH2 . TRP B 1 269 ? 51.243 89.649 89.728 1.00 33.33 ? 305 TRP B CH2 1 ATOM 8085 N N . ALA B 1 270 ? 57.949 88.876 91.792 1.00 35.94 ? 306 ALA B N 1 ATOM 8086 C CA . ALA B 1 270 ? 58.953 89.239 92.791 1.00 29.31 ? 306 ALA B CA 1 ATOM 8087 C C . ALA B 1 270 ? 58.326 89.342 94.175 1.00 33.01 ? 306 ALA B C 1 ATOM 8088 O O . ALA B 1 270 ? 58.911 88.900 95.166 1.00 31.80 ? 306 ALA B O 1 ATOM 8089 C CB . ALA B 1 270 ? 59.638 90.553 92.412 1.00 30.71 ? 306 ALA B CB 1 ATOM 8090 N N . THR B 1 271 ? 57.135 89.933 94.236 1.00 32.21 ? 307 THR B N 1 ATOM 8091 C CA . THR B 1 271 ? 56.364 90.025 95.474 1.00 32.29 ? 307 THR B CA 1 ATOM 8092 C C . THR B 1 271 ? 54.887 89.934 95.131 1.00 38.40 ? 307 THR B C 1 ATOM 8093 O O . THR B 1 271 ? 54.526 89.694 93.980 1.00 33.12 ? 307 THR B O 1 ATOM 8094 C CB . THR B 1 271 ? 56.583 91.361 96.223 1.00 33.72 ? 307 THR B CB 1 ATOM 8095 O OG1 . THR B 1 271 ? 55.959 92.428 95.497 1.00 35.25 ? 307 THR B OG1 1 ATOM 8096 C CG2 . THR B 1 271 ? 58.066 91.664 96.401 1.00 38.66 ? 307 THR B CG2 1 ATOM 8097 N N . GLN B 1 272 ? 54.025 90.151 96.120 1.00 36.40 ? 308 GLN B N 1 ATOM 8098 C CA . GLN B 1 272 ? 52.592 90.126 95.860 1.00 37.61 ? 308 GLN B CA 1 ATOM 8099 C C . GLN B 1 272 ? 52.235 91.186 94.829 1.00 38.43 ? 308 GLN B C 1 ATOM 8100 O O . GLN B 1 272 ? 51.234 91.054 94.127 1.00 37.71 ? 308 GLN B O 1 ATOM 8101 C CB . GLN B 1 272 ? 51.789 90.363 97.142 1.00 40.83 ? 308 GLN B CB 1 ATOM 8102 C CG . GLN B 1 272 ? 52.116 89.416 98.290 1.00 49.56 ? 308 GLN B CG 1 ATOM 8103 C CD . GLN B 1 272 ? 51.797 87.967 97.959 1.00 50.13 ? 308 GLN B CD 1 ATOM 8104 O OE1 . GLN B 1 272 ? 51.226 87.675 96.905 1.00 49.22 ? 308 GLN B OE1 1 ATOM 8105 N NE2 . GLN B 1 272 ? 52.170 87.050 98.854 1.00 47.78 ? 308 GLN B NE2 1 ATOM 8106 N N . GLU B 1 273 ? 53.052 92.237 94.735 1.00 34.60 ? 309 GLU B N 1 ATOM 8107 C CA . GLU B 1 273 ? 52.693 93.390 93.899 1.00 38.61 ? 309 GLU B CA 1 ATOM 8108 C C . GLU B 1 273 ? 53.775 93.842 92.923 1.00 37.69 ? 309 GLU B C 1 ATOM 8109 O O . GLU B 1 273 ? 53.728 94.961 92.400 1.00 38.78 ? 309 GLU B O 1 ATOM 8110 C CB . GLU B 1 273 ? 52.279 94.581 94.777 1.00 47.49 ? 309 GLU B CB 1 ATOM 8111 C CG . GLU B 1 273 ? 51.058 94.318 95.646 1.00 51.57 ? 309 GLU B CG 1 ATOM 8112 C CD . GLU B 1 273 ? 50.752 95.467 96.598 1.00 63.19 ? 309 GLU B CD 1 ATOM 8113 O OE1 . GLU B 1 273 ? 51.692 96.219 96.960 1.00 60.03 ? 309 GLU B OE1 1 ATOM 8114 O OE2 . GLU B 1 273 ? 49.566 95.615 96.977 1.00 61.39 ? 309 GLU B OE2 1 ATOM 8115 N N . ARG B 1 274 ? 54.746 92.978 92.663 1.00 36.56 ? 310 ARG B N 1 ATOM 8116 C CA . ARG B 1 274 ? 55.806 93.321 91.728 1.00 34.42 ? 310 ARG B CA 1 ATOM 8117 C C . ARG B 1 274 ? 56.115 92.134 90.837 1.00 38.82 ? 310 ARG B C 1 ATOM 8118 O O . ARG B 1 274 ? 56.425 91.035 91.319 1.00 34.93 ? 310 ARG B O 1 ATOM 8119 C CB . ARG B 1 274 ? 57.064 93.766 92.466 1.00 31.28 ? 310 ARG B CB 1 ATOM 8120 C CG . ARG B 1 274 ? 58.275 93.865 91.580 1.00 34.42 ? 310 ARG B CG 1 ATOM 8121 C CD . ARG B 1 274 ? 59.436 94.514 92.302 1.00 35.14 ? 310 ARG B CD 1 ATOM 8122 N NE . ARG B 1 274 ? 59.117 95.883 92.683 1.00 37.31 ? 310 ARG B NE 1 ATOM 8123 C CZ . ARG B 1 274 ? 59.920 96.675 93.381 1.00 45.60 ? 310 ARG B CZ 1 ATOM 8124 N NH1 . ARG B 1 274 ? 59.529 97.911 93.672 1.00 49.02 ? 310 ARG B NH1 1 ATOM 8125 N NH2 . ARG B 1 274 ? 61.107 96.239 93.791 1.00 40.63 ? 310 ARG B NH2 1 ATOM 8126 N N . ILE B 1 275 ? 56.006 92.361 89.537 1.00 35.83 ? 311 ILE B N 1 ATOM 8127 C CA . ILE B 1 275 ? 56.283 91.328 88.555 1.00 36.04 ? 311 ILE B CA 1 ATOM 8128 C C . ILE B 1 275 ? 57.461 91.783 87.710 1.00 36.27 ? 311 ILE B C 1 ATOM 8129 O O . ILE B 1 275 ? 57.612 92.973 87.416 1.00 36.70 ? 311 ILE B O 1 ATOM 8130 C CB . ILE B 1 275 ? 55.031 91.024 87.697 1.00 35.12 ? 311 ILE B CB 1 ATOM 8131 C CG1 . ILE B 1 275 ? 55.254 89.788 86.817 1.00 33.22 ? 311 ILE B CG1 1 ATOM 8132 C CG2 . ILE B 1 275 ? 54.654 92.231 86.859 1.00 40.95 ? 311 ILE B CG2 1 ATOM 8133 C CD1 . ILE B 1 275 ? 53.955 89.123 86.405 1.00 35.94 ? 311 ILE B CD1 1 ATOM 8134 N N . SER B 1 276 ? 58.325 90.833 87.374 1.00 34.62 ? 312 SER B N 1 ATOM 8135 C CA . SER B 1 276 ? 59.495 91.091 86.553 1.00 34.65 ? 312 SER B CA 1 ATOM 8136 C C . SER B 1 276 ? 59.250 90.471 85.182 1.00 35.02 ? 312 SER B C 1 ATOM 8137 O O . SER B 1 276 ? 58.857 89.310 85.103 1.00 30.44 ? 312 SER B O 1 ATOM 8138 C CB . SER B 1 276 ? 60.709 90.419 87.181 1.00 33.85 ? 312 SER B CB 1 ATOM 8139 O OG . SER B 1 276 ? 61.842 90.558 86.344 1.00 38.83 ? 312 SER B OG 1 ATOM 8140 N N . LEU B 1 277 ? 59.472 91.237 84.114 1.00 34.47 ? 313 LEU B N 1 ATOM 8141 C CA . LEU B 1 277 ? 59.293 90.740 82.748 1.00 33.21 ? 313 LEU B CA 1 ATOM 8142 C C . LEU B 1 277 ? 60.565 90.951 81.955 1.00 34.69 ? 313 LEU B C 1 ATOM 8143 O O . LEU B 1 277 ? 61.076 92.067 81.898 1.00 36.30 ? 313 LEU B O 1 ATOM 8144 C CB . LEU B 1 277 ? 58.163 91.480 82.050 1.00 34.14 ? 313 LEU B CB 1 ATOM 8145 C CG . LEU B 1 277 ? 56.834 91.458 82.794 1.00 37.42 ? 313 LEU B CG 1 ATOM 8146 C CD1 . LEU B 1 277 ? 55.832 92.359 82.087 1.00 43.60 ? 313 LEU B CD1 1 ATOM 8147 C CD2 . LEU B 1 277 ? 56.325 90.046 82.866 1.00 35.49 ? 313 LEU B CD2 1 ATOM 8148 N N . GLN B 1 278 ? 61.077 89.886 81.348 1.00 31.48 ? 314 GLN B N 1 ATOM 8149 C CA . GLN B 1 278 ? 62.217 90.011 80.441 1.00 32.00 ? 314 GLN B CA 1 ATOM 8150 C C . GLN B 1 278 ? 61.784 89.878 78.980 1.00 32.86 ? 314 GLN B C 1 ATOM 8151 O O . GLN B 1 278 ? 61.013 88.987 78.635 1.00 32.05 ? 314 GLN B O 1 ATOM 8152 C CB . GLN B 1 278 ? 63.308 88.997 80.780 1.00 31.96 ? 314 GLN B CB 1 ATOM 8153 C CG . GLN B 1 278 ? 64.286 89.488 81.836 1.00 38.04 ? 314 GLN B CG 1 ATOM 8154 C CD . GLN B 1 278 ? 65.313 88.440 82.218 1.00 41.57 ? 314 GLN B CD 1 ATOM 8155 O OE1 . GLN B 1 278 ? 66.456 88.474 81.758 1.00 38.48 ? 314 GLN B OE1 1 ATOM 8156 N NE2 . GLN B 1 278 ? 64.908 87.500 83.066 1.00 39.41 ? 314 GLN B NE2 1 ATOM 8157 N N . TRP B 1 279 ? 62.288 90.780 78.141 1.00 30.85 ? 315 TRP B N 1 ATOM 8158 C CA . TRP B 1 279 ? 61.951 90.847 76.727 1.00 30.78 ? 315 TRP B CA 1 ATOM 8159 C C . TRP B 1 279 ? 63.245 90.728 75.945 1.00 31.72 ? 315 TRP B C 1 ATOM 8160 O O . TRP B 1 279 ? 64.300 91.137 76.425 1.00 33.03 ? 315 TRP B O 1 ATOM 8161 C CB . TRP B 1 279 ? 61.341 92.199 76.388 1.00 30.47 ? 315 TRP B CB 1 ATOM 8162 C CG . TRP B 1 279 ? 60.096 92.564 77.140 1.00 29.83 ? 315 TRP B CG 1 ATOM 8163 C CD1 . TRP B 1 279 ? 60.019 93.253 78.315 1.00 26.31 ? 315 TRP B CD1 1 ATOM 8164 C CD2 . TRP B 1 279 ? 58.751 92.319 76.731 1.00 27.96 ? 315 TRP B CD2 1 ATOM 8165 N NE1 . TRP B 1 279 ? 58.706 93.414 78.682 1.00 29.86 ? 315 TRP B NE1 1 ATOM 8166 C CE2 . TRP B 1 279 ? 57.908 92.855 77.722 1.00 31.32 ? 315 TRP B CE2 1 ATOM 8167 C CE3 . TRP B 1 279 ? 58.176 91.681 75.630 1.00 29.81 ? 315 TRP B CE3 1 ATOM 8168 C CZ2 . TRP B 1 279 ? 56.531 92.775 77.642 1.00 32.80 ? 315 TRP B CZ2 1 ATOM 8169 C CZ3 . TRP B 1 279 ? 56.813 91.602 75.555 1.00 30.72 ? 315 TRP B CZ3 1 ATOM 8170 C CH2 . TRP B 1 279 ? 56.001 92.155 76.546 1.00 31.72 ? 315 TRP B CH2 1 ATOM 8171 N N . LEU B 1 280 ? 63.165 90.183 74.739 1.00 29.36 ? 316 LEU B N 1 ATOM 8172 C CA . LEU B 1 280 ? 64.359 89.949 73.918 1.00 30.32 ? 316 LEU B CA 1 ATOM 8173 C C . LEU B 1 280 ? 64.070 90.391 72.492 1.00 29.11 ? 316 LEU B C 1 ATOM 8174 O O . LEU B 1 280 ? 63.028 90.034 71.941 1.00 28.25 ? 316 LEU B O 1 ATOM 8175 C CB . LEU B 1 280 ? 64.717 88.455 73.952 1.00 28.94 ? 316 LEU B CB 1 ATOM 8176 C CG . LEU B 1 280 ? 65.915 87.922 73.169 1.00 29.88 ? 316 LEU B CG 1 ATOM 8177 C CD1 . LEU B 1 280 ? 67.217 88.447 73.746 1.00 29.68 ? 316 LEU B CD1 1 ATOM 8178 C CD2 . LEU B 1 280 ? 65.901 86.394 73.186 1.00 30.52 ? 316 LEU B CD2 1 ATOM 8179 N N . ARG B 1 281 ? 64.963 91.175 71.887 1.00 30.72 ? 317 ARG B N 1 ATOM 8180 C CA . ARG B 1 281 ? 64.768 91.570 70.490 1.00 29.99 ? 317 ARG B CA 1 ATOM 8181 C C . ARG B 1 281 ? 64.877 90.359 69.560 1.00 31.49 ? 317 ARG B C 1 ATOM 8182 O O . ARG B 1 281 ? 65.519 89.377 69.906 1.00 29.17 ? 317 ARG B O 1 ATOM 8183 C CB . ARG B 1 281 ? 65.761 92.654 70.061 1.00 29.49 ? 317 ARG B CB 1 ATOM 8184 C CG . ARG B 1 281 ? 65.356 94.051 70.478 1.00 34.87 ? 317 ARG B CG 1 ATOM 8185 C CD . ARG B 1 281 ? 66.180 95.105 69.750 1.00 37.84 ? 317 ARG B CD 1 ATOM 8186 N NE . ARG B 1 281 ? 65.872 96.442 70.249 1.00 42.77 ? 317 ARG B NE 1 ATOM 8187 C CZ . ARG B 1 281 ? 66.773 97.406 70.406 1.00 41.76 ? 317 ARG B CZ 1 ATOM 8188 N NH1 . ARG B 1 281 ? 68.041 97.175 70.098 1.00 40.13 ? 317 ARG B NH1 1 ATOM 8189 N NH2 . ARG B 1 281 ? 66.404 98.599 70.869 1.00 38.46 ? 317 ARG B NH2 1 ATOM 8190 N N . ARG B 1 282 ? 64.258 90.432 68.382 1.00 30.89 ? 318 ARG B N 1 ATOM 8191 C CA . ARG B 1 282 ? 64.309 89.309 67.450 1.00 31.06 ? 318 ARG B CA 1 ATOM 8192 C C . ARG B 1 282 ? 65.744 89.005 67.057 1.00 29.97 ? 318 ARG B C 1 ATOM 8193 O O . ARG B 1 282 ? 66.123 87.844 66.895 1.00 32.59 ? 318 ARG B O 1 ATOM 8194 C CB . ARG B 1 282 ? 63.442 89.539 66.207 1.00 28.96 ? 318 ARG B CB 1 ATOM 8195 C CG . ARG B 1 282 ? 63.456 88.325 65.272 1.00 31.73 ? 318 ARG B CG 1 ATOM 8196 C CD . ARG B 1 282 ? 62.425 88.389 64.133 1.00 32.86 ? 318 ARG B CD 1 ATOM 8197 N NE . ARG B 1 282 ? 62.510 87.185 63.301 1.00 28.52 ? 318 ARG B NE 1 ATOM 8198 C CZ . ARG B 1 282 ? 61.563 86.764 62.468 1.00 32.55 ? 318 ARG B CZ 1 ATOM 8199 N NH1 . ARG B 1 282 ? 60.436 87.454 62.322 1.00 29.07 ? 318 ARG B NH1 1 ATOM 8200 N NH2 . ARG B 1 282 ? 61.747 85.646 61.765 1.00 27.86 ? 318 ARG B NH2 1 ATOM 8201 N N . ILE B 1 283 ? 66.545 90.047 66.878 1.00 30.24 ? 319 ILE B N 1 ATOM 8202 C CA . ILE B 1 283 ? 67.991 89.855 66.806 1.00 30.28 ? 319 ILE B CA 1 ATOM 8203 C C . ILE B 1 283 ? 68.449 89.724 68.242 1.00 32.52 ? 319 ILE B C 1 ATOM 8204 O O . ILE B 1 283 ? 68.460 90.710 68.987 1.00 33.57 ? 319 ILE B O 1 ATOM 8205 C CB . ILE B 1 283 ? 68.708 91.038 66.121 1.00 34.87 ? 319 ILE B CB 1 ATOM 8206 C CG1 . ILE B 1 283 ? 68.298 91.117 64.651 1.00 36.18 ? 319 ILE B CG1 1 ATOM 8207 C CG2 . ILE B 1 283 ? 70.224 90.868 66.214 1.00 33.70 ? 319 ILE B CG2 1 ATOM 8208 C CD1 . ILE B 1 283 ? 68.517 89.810 63.909 1.00 39.99 ? 319 ILE B CD1 1 ATOM 8209 N N . GLN B 1 284 ? 68.799 88.503 68.641 1.00 31.91 ? 320 GLN B N 1 ATOM 8210 C CA . GLN B 1 284 ? 68.850 88.146 70.058 1.00 33.02 ? 320 GLN B CA 1 ATOM 8211 C C . GLN B 1 284 ? 70.111 88.641 70.777 1.00 38.15 ? 320 GLN B C 1 ATOM 8212 O O . GLN B 1 284 ? 70.747 87.911 71.550 1.00 35.59 ? 320 GLN B O 1 ATOM 8213 C CB . GLN B 1 284 ? 68.630 86.647 70.207 1.00 30.49 ? 320 GLN B CB 1 ATOM 8214 C CG . GLN B 1 284 ? 67.263 86.228 69.672 1.00 27.98 ? 320 GLN B CG 1 ATOM 8215 C CD . GLN B 1 284 ? 67.014 84.748 69.819 1.00 33.11 ? 320 GLN B CD 1 ATOM 8216 O OE1 . GLN B 1 284 ? 67.343 84.160 70.844 1.00 33.05 ? 320 GLN B OE1 1 ATOM 8217 N NE2 . GLN B 1 284 ? 66.442 84.134 68.790 1.00 29.64 ? 320 GLN B NE2 1 ATOM 8218 N N . ASN B 1 285 ? 70.396 89.919 70.528 1.00 38.71 ? 321 ASN B N 1 ATOM 8219 C CA . ASN B 1 285 ? 71.610 90.636 70.889 1.00 38.11 ? 321 ASN B CA 1 ATOM 8220 C C . ASN B 1 285 ? 71.404 91.451 72.140 1.00 35.71 ? 321 ASN B C 1 ATOM 8221 O O . ASN B 1 285 ? 72.352 91.929 72.761 1.00 37.23 ? 321 ASN B O 1 ATOM 8222 C CB . ASN B 1 285 ? 71.904 91.650 69.757 1.00 34.43 ? 321 ASN B CB 1 ATOM 8223 C CG . ASN B 1 285 ? 73.163 91.331 69.020 1.00 45.61 ? 321 ASN B CG 1 ATOM 8224 O OD1 . ASN B 1 285 ? 73.857 90.382 69.379 1.00 53.72 ? 321 ASN B OD1 1 ATOM 8225 N ND2 . ASN B 1 285 ? 73.475 92.106 67.974 1.00 51.91 ? 321 ASN B ND2 1 ATOM 8226 N N . TYR B 1 286 ? 70.142 91.646 72.477 1.00 35.00 ? 322 TYR B N 1 ATOM 8227 C CA . TYR B 1 286 ? 69.744 92.748 73.322 1.00 34.32 ? 322 TYR B CA 1 ATOM 8228 C C . TYR B 1 286 ? 68.492 92.335 74.065 1.00 35.47 ? 322 TYR B C 1 ATOM 8229 O O . TYR B 1 286 ? 67.525 91.896 73.447 1.00 33.60 ? 322 TYR B O 1 ATOM 8230 C CB . TYR B 1 286 ? 69.433 93.945 72.412 1.00 34.83 ? 322 TYR B CB 1 ATOM 8231 C CG . TYR B 1 286 ? 69.153 95.252 73.116 1.00 38.33 ? 322 TYR B CG 1 ATOM 8232 C CD1 . TYR B 1 286 ? 70.178 96.154 73.385 1.00 39.94 ? 322 TYR B CD1 1 ATOM 8233 C CD2 . TYR B 1 286 ? 67.864 95.602 73.480 1.00 37.42 ? 322 TYR B CD2 1 ATOM 8234 C CE1 . TYR B 1 286 ? 69.920 97.359 74.022 1.00 42.47 ? 322 TYR B CE1 1 ATOM 8235 C CE2 . TYR B 1 286 ? 67.600 96.802 74.115 1.00 37.97 ? 322 TYR B CE2 1 ATOM 8236 C CZ . TYR B 1 286 ? 68.630 97.672 74.380 1.00 38.85 ? 322 TYR B CZ 1 ATOM 8237 O OH . TYR B 1 286 ? 68.360 98.863 75.003 1.00 44.61 ? 322 TYR B OH 1 ATOM 8238 N N . SER B 1 287 ? 68.502 92.461 75.387 1.00 32.63 ? 323 SER B N 1 ATOM 8239 C CA . SER B 1 287 ? 67.301 92.189 76.169 1.00 35.71 ? 323 SER B CA 1 ATOM 8240 C C . SER B 1 287 ? 67.084 93.242 77.247 1.00 33.07 ? 323 SER B C 1 ATOM 8241 O O . SER B 1 287 ? 68.024 93.888 77.703 1.00 33.91 ? 323 SER B O 1 ATOM 8242 C CB . SER B 1 287 ? 67.308 90.773 76.781 1.00 36.86 ? 323 SER B CB 1 ATOM 8243 O OG . SER B 1 287 ? 68.365 90.595 77.697 1.00 39.09 ? 323 SER B OG 1 ATOM 8244 N N . VAL B 1 288 ? 65.828 93.421 77.625 1.00 34.45 ? 324 VAL B N 1 ATOM 8245 C CA . VAL B 1 288 ? 65.471 94.361 78.677 1.00 34.71 ? 324 VAL B CA 1 ATOM 8246 C C . VAL B 1 288 ? 64.657 93.656 79.737 1.00 33.34 ? 324 VAL B C 1 ATOM 8247 O O . VAL B 1 288 ? 63.683 92.981 79.423 1.00 32.61 ? 324 VAL B O 1 ATOM 8248 C CB . VAL B 1 288 ? 64.601 95.519 78.145 1.00 30.08 ? 324 VAL B CB 1 ATOM 8249 C CG1 . VAL B 1 288 ? 64.330 96.535 79.266 1.00 34.73 ? 324 VAL B CG1 1 ATOM 8250 C CG2 . VAL B 1 288 ? 65.290 96.192 76.972 1.00 39.54 ? 324 VAL B CG2 1 ATOM 8251 N N . MET B 1 289 ? 65.043 93.831 80.993 1.00 33.59 ? 325 MET B N 1 ATOM 8252 C CA . MET B 1 289 ? 64.202 93.406 82.111 1.00 34.90 ? 325 MET B CA 1 ATOM 8253 C C . MET B 1 289 ? 63.394 94.585 82.658 1.00 36.13 ? 325 MET B C 1 ATOM 8254 O O . MET B 1 289 ? 63.960 95.622 83.007 1.00 38.89 ? 325 MET B O 1 ATOM 8255 C CB . MET B 1 289 ? 65.059 92.826 83.232 1.00 33.96 ? 325 MET B CB 1 ATOM 8256 C CG . MET B 1 289 ? 64.244 92.448 84.468 1.00 33.83 ? 325 MET B CG 1 ATOM 8257 S SD . MET B 1 289 ? 65.279 91.740 85.764 1.00 43.97 ? 325 MET B SD 1 ATOM 8258 C CE . MET B 1 289 ? 65.812 90.248 84.946 1.00 42.23 ? 325 MET B CE 1 ATOM 8259 N N . ASP B 1 290 ? 62.080 94.420 82.739 1.00 34.31 ? 326 ASP B N 1 ATOM 8260 C CA . ASP B 1 290 ? 61.183 95.455 83.246 1.00 37.10 ? 326 ASP B CA 1 ATOM 8261 C C . ASP B 1 290 ? 60.691 95.090 84.638 1.00 39.75 ? 326 ASP B C 1 ATOM 8262 O O . ASP B 1 290 ? 60.275 93.957 84.861 1.00 36.61 ? 326 ASP B O 1 ATOM 8263 C CB . ASP B 1 290 ? 59.960 95.559 82.334 1.00 38.86 ? 326 ASP B CB 1 ATOM 8264 C CG . ASP B 1 290 ? 59.869 96.890 81.625 1.00 46.65 ? 326 ASP B CG 1 ATOM 8265 O OD1 . ASP B 1 290 ? 60.661 97.796 81.962 1.00 46.60 ? 326 ASP B OD1 1 ATOM 8266 O OD2 . ASP B 1 290 ? 58.996 97.032 80.736 1.00 48.28 ? 326 ASP B OD2 1 ATOM 8267 N N . ILE B 1 291 ? 60.729 96.039 85.572 1.00 42.23 ? 327 ILE B N 1 ATOM 8268 C CA . ILE B 1 291 ? 60.112 95.840 86.885 1.00 39.70 ? 327 ILE B CA 1 ATOM 8269 C C . ILE B 1 291 ? 58.775 96.585 86.986 1.00 40.16 ? 327 ILE B C 1 ATOM 8270 O O . ILE B 1 291 ? 58.732 97.807 86.912 1.00 40.46 ? 327 ILE B O 1 ATOM 8271 C CB . ILE B 1 291 ? 61.029 96.282 88.040 1.00 39.34 ? 327 ILE B CB 1 ATOM 8272 C CG1 . ILE B 1 291 ? 62.219 95.338 88.175 1.00 39.92 ? 327 ILE B CG1 1 ATOM 8273 C CG2 . ILE B 1 291 ? 60.269 96.251 89.346 1.00 38.74 ? 327 ILE B CG2 1 ATOM 8274 C CD1 . ILE B 1 291 ? 63.381 95.702 87.309 1.00 45.59 ? 327 ILE B CD1 1 ATOM 8275 N N . CYS B 1 292 ? 57.691 95.834 87.160 1.00 42.02 ? 328 CYS B N 1 ATOM 8276 C CA . CYS B 1 292 ? 56.335 96.387 87.124 1.00 43.77 ? 328 CYS B CA 1 ATOM 8277 C C . CYS B 1 292 ? 55.636 96.321 88.475 1.00 41.65 ? 328 CYS B C 1 ATOM 8278 O O . CYS B 1 292 ? 55.408 95.226 88.998 1.00 41.97 ? 328 CYS B O 1 ATOM 8279 C CB . CYS B 1 292 ? 55.485 95.641 86.085 1.00 43.67 ? 328 CYS B CB 1 ATOM 8280 S SG . CYS B 1 292 ? 56.225 95.583 84.425 1.00 53.46 ? 328 CYS B SG 1 ATOM 8281 N N . ASP B 1 293 ? 55.285 97.490 89.023 1.00 43.41 ? 329 ASP B N 1 ATOM 8282 C CA . ASP B 1 293 ? 54.612 97.582 90.323 1.00 41.49 ? 329 ASP B CA 1 ATOM 8283 C C . ASP B 1 293 ? 53.129 97.913 90.220 1.00 41.54 ? 329 ASP B C 1 ATOM 8284 O O . ASP B 1 293 ? 52.705 98.720 89.390 1.00 43.46 ? 329 ASP B O 1 ATOM 8285 C CB . ASP B 1 293 ? 55.286 98.613 91.235 1.00 43.12 ? 329 ASP B CB 1 ATOM 8286 C CG . ASP B 1 293 ? 56.704 98.239 91.589 1.00 47.30 ? 329 ASP B CG 1 ATOM 8287 O OD1 . ASP B 1 293 ? 57.013 97.031 91.559 1.00 46.09 ? 329 ASP B OD1 1 ATOM 8288 O OD2 . ASP B 1 293 ? 57.515 99.146 91.895 1.00 49.96 ? 329 ASP B OD2 1 ATOM 8289 N N . TYR B 1 294 ? 52.352 97.286 91.095 1.00 40.28 ? 330 TYR B N 1 ATOM 8290 C CA . TYR B 1 294 ? 50.917 97.496 91.164 1.00 43.16 ? 330 TYR B CA 1 ATOM 8291 C C . TYR B 1 294 ? 50.628 98.805 91.879 1.00 46.42 ? 330 TYR B C 1 ATOM 8292 O O . TYR B 1 294 ? 51.235 99.105 92.898 1.00 47.34 ? 330 TYR B O 1 ATOM 8293 C CB . TYR B 1 294 ? 50.257 96.345 91.923 1.00 43.00 ? 330 TYR B CB 1 ATOM 8294 C CG . TYR B 1 294 ? 48.752 96.441 91.982 1.00 45.47 ? 330 TYR B CG 1 ATOM 8295 C CD1 . TYR B 1 294 ? 47.990 96.348 90.827 1.00 48.60 ? 330 TYR B CD1 1 ATOM 8296 C CD2 . TYR B 1 294 ? 48.091 96.626 93.192 1.00 53.72 ? 330 TYR B CD2 1 ATOM 8297 C CE1 . TYR B 1 294 ? 46.612 96.432 90.868 1.00 50.37 ? 330 TYR B CE1 1 ATOM 8298 C CE2 . TYR B 1 294 ? 46.709 96.712 93.245 1.00 55.23 ? 330 TYR B CE2 1 ATOM 8299 C CZ . TYR B 1 294 ? 45.976 96.614 92.077 1.00 56.27 ? 330 TYR B CZ 1 ATOM 8300 O OH . TYR B 1 294 ? 44.601 96.695 92.110 1.00 60.67 ? 330 TYR B OH 1 ATOM 8301 N N . ASP B 1 295 ? 49.702 99.581 91.333 1.00 54.16 ? 331 ASP B N 1 ATOM 8302 C CA . ASP B 1 295 ? 49.282 100.835 91.944 1.00 57.75 ? 331 ASP B CA 1 ATOM 8303 C C . ASP B 1 295 ? 47.883 100.639 92.514 1.00 57.31 ? 331 ASP B C 1 ATOM 8304 O O . ASP B 1 295 ? 46.906 100.609 91.765 1.00 59.29 ? 331 ASP B O 1 ATOM 8305 C CB . ASP B 1 295 ? 49.267 101.947 90.892 1.00 60.69 ? 331 ASP B CB 1 ATOM 8306 C CG . ASP B 1 295 ? 49.107 103.328 91.501 1.00 66.60 ? 331 ASP B CG 1 ATOM 8307 O OD1 . ASP B 1 295 ? 48.847 103.414 92.726 1.00 67.81 ? 331 ASP B OD1 1 ATOM 8308 O OD2 . ASP B 1 295 ? 49.239 104.323 90.750 1.00 66.20 ? 331 ASP B OD2 1 ATOM 8309 N N . GLU B 1 296 ? 47.791 100.499 93.834 1.00 59.31 ? 332 GLU B N 1 ATOM 8310 C CA . GLU B 1 296 ? 46.526 100.155 94.488 1.00 63.38 ? 332 GLU B CA 1 ATOM 8311 C C . GLU B 1 296 ? 45.380 101.112 94.143 1.00 66.29 ? 332 GLU B C 1 ATOM 8312 O O . GLU B 1 296 ? 44.231 100.687 93.993 1.00 66.43 ? 332 GLU B O 1 ATOM 8313 C CB . GLU B 1 296 ? 46.700 100.057 96.011 1.00 61.57 ? 332 GLU B CB 1 ATOM 8314 N N . SER B 1 297 ? 45.686 102.399 94.016 1.00 65.06 ? 333 SER B N 1 ATOM 8315 C CA . SER B 1 297 ? 44.652 103.373 93.690 1.00 66.02 ? 333 SER B CA 1 ATOM 8316 C C . SER B 1 297 ? 44.307 103.307 92.207 1.00 69.16 ? 333 SER B C 1 ATOM 8317 O O . SER B 1 297 ? 43.146 103.121 91.838 1.00 70.73 ? 333 SER B O 1 ATOM 8318 C CB . SER B 1 297 ? 45.078 104.793 94.085 1.00 70.34 ? 333 SER B CB 1 ATOM 8319 O OG . SER B 1 297 ? 45.925 105.383 93.109 1.00 72.31 ? 333 SER B OG 1 ATOM 8320 N N . SER B 1 298 ? 45.323 103.453 91.361 1.00 66.67 ? 334 SER B N 1 ATOM 8321 C CA . SER B 1 298 ? 45.136 103.404 89.914 1.00 66.08 ? 334 SER B CA 1 ATOM 8322 C C . SER B 1 298 ? 44.454 102.112 89.484 1.00 64.86 ? 334 SER B C 1 ATOM 8323 O O . SER B 1 298 ? 43.570 102.124 88.634 1.00 66.90 ? 334 SER B O 1 ATOM 8324 C CB . SER B 1 298 ? 46.488 103.533 89.198 1.00 67.21 ? 334 SER B CB 1 ATOM 8325 O OG . SER B 1 298 ? 46.351 103.386 87.793 1.00 65.61 ? 334 SER B OG 1 ATOM 8326 N N . GLY B 1 299 ? 44.870 101.000 90.080 1.00 64.21 ? 335 GLY B N 1 ATOM 8327 C CA . GLY B 1 299 ? 44.428 99.688 89.644 1.00 61.47 ? 335 GLY B CA 1 ATOM 8328 C C . GLY B 1 299 ? 45.288 99.196 88.492 1.00 57.19 ? 335 GLY B C 1 ATOM 8329 O O . GLY B 1 299 ? 45.081 98.096 87.976 1.00 53.88 ? 335 GLY B O 1 ATOM 8330 N N . ARG B 1 300 ? 46.262 100.013 88.096 1.00 57.49 ? 336 ARG B N 1 ATOM 8331 C CA . ARG B 1 300 ? 47.113 99.705 86.953 1.00 55.86 ? 336 ARG B CA 1 ATOM 8332 C C . ARG B 1 300 ? 48.493 99.206 87.364 1.00 53.29 ? 336 ARG B C 1 ATOM 8333 O O . ARG B 1 300 ? 48.857 99.259 88.541 1.00 50.99 ? 336 ARG B O 1 ATOM 8334 C CB . ARG B 1 300 ? 47.257 100.929 86.045 1.00 60.52 ? 336 ARG B CB 1 ATOM 8335 C CG . ARG B 1 300 ? 45.939 101.432 85.477 1.00 61.92 ? 336 ARG B CG 1 ATOM 8336 C CD . ARG B 1 300 ? 46.070 101.807 84.005 1.00 67.71 ? 336 ARG B CD 1 ATOM 8337 N NE . ARG B 1 300 ? 45.123 101.060 83.178 1.00 71.67 ? 336 ARG B NE 1 ATOM 8338 C CZ . ARG B 1 300 ? 45.462 100.329 82.120 1.00 71.27 ? 336 ARG B CZ 1 ATOM 8339 N NH1 . ARG B 1 300 ? 46.734 100.251 81.745 1.00 66.30 ? 336 ARG B NH1 1 ATOM 8340 N NH2 . ARG B 1 300 ? 44.525 99.680 81.434 1.00 66.46 ? 336 ARG B NH2 1 ATOM 8341 N N . TRP B 1 301 ? 49.247 98.721 86.380 1.00 48.53 ? 337 TRP B N 1 ATOM 8342 C CA . TRP B 1 301 ? 50.623 98.278 86.582 1.00 47.21 ? 337 TRP B CA 1 ATOM 8343 C C . TRP B 1 301 ? 51.576 99.212 85.849 1.00 49.70 ? 337 TRP B C 1 ATOM 8344 O O . TRP B 1 301 ? 51.395 99.460 84.659 1.00 53.48 ? 337 TRP B O 1 ATOM 8345 C CB . TRP B 1 301 ? 50.802 96.845 86.064 1.00 46.03 ? 337 TRP B CB 1 ATOM 8346 C CG . TRP B 1 301 ? 50.057 95.831 86.865 1.00 38.91 ? 337 TRP B CG 1 ATOM 8347 C CD1 . TRP B 1 301 ? 48.745 95.469 86.723 1.00 36.77 ? 337 TRP B CD1 1 ATOM 8348 C CD2 . TRP B 1 301 ? 50.576 95.049 87.943 1.00 38.77 ? 337 TRP B CD2 1 ATOM 8349 N NE1 . TRP B 1 301 ? 48.420 94.506 87.648 1.00 37.22 ? 337 TRP B NE1 1 ATOM 8350 C CE2 . TRP B 1 301 ? 49.526 94.239 88.416 1.00 35.55 ? 337 TRP B CE2 1 ATOM 8351 C CE3 . TRP B 1 301 ? 51.830 94.956 88.559 1.00 39.58 ? 337 TRP B CE3 1 ATOM 8352 C CZ2 . TRP B 1 301 ? 49.692 93.348 89.472 1.00 35.71 ? 337 TRP B CZ2 1 ATOM 8353 C CZ3 . TRP B 1 301 ? 51.992 94.068 89.604 1.00 37.54 ? 337 TRP B CZ3 1 ATOM 8354 C CH2 . TRP B 1 301 ? 50.932 93.274 90.047 1.00 34.98 ? 337 TRP B CH2 1 ATOM 8355 N N . ASN B 1 302 ? 52.582 99.730 86.551 1.00 48.75 ? 338 ASN B N 1 ATOM 8356 C CA . ASN B 1 302 ? 53.548 100.641 85.938 1.00 48.87 ? 338 ASN B CA 1 ATOM 8357 C C . ASN B 1 302 ? 54.988 100.135 85.970 1.00 48.29 ? 338 ASN B C 1 ATOM 8358 O O . ASN B 1 302 ? 55.437 99.574 86.970 1.00 51.45 ? 338 ASN B O 1 ATOM 8359 C CB . ASN B 1 302 ? 53.470 102.021 86.591 1.00 51.70 ? 338 ASN B CB 1 ATOM 8360 C CG . ASN B 1 302 ? 52.101 102.662 86.439 1.00 57.13 ? 338 ASN B CG 1 ATOM 8361 O OD1 . ASN B 1 302 ? 51.526 102.688 85.346 1.00 60.69 ? 338 ASN B OD1 1 ATOM 8362 N ND2 . ASN B 1 302 ? 51.567 103.179 87.541 1.00 52.48 ? 338 ASN B ND2 1 ATOM 8363 N N . CYS B 1 303 ? 55.705 100.350 84.871 1.00 47.17 ? 339 CYS B N 1 ATOM 8364 C CA . CYS B 1 303 ? 57.080 99.886 84.712 1.00 49.21 ? 339 CYS B CA 1 ATOM 8365 C C . CYS B 1 303 ? 58.031 101.066 84.544 1.00 51.54 ? 339 CYS B C 1 ATOM 8366 O O . CYS B 1 303 ? 58.382 101.424 83.412 1.00 55.62 ? 339 CYS B O 1 ATOM 8367 C CB . CYS B 1 303 ? 57.216 98.994 83.461 1.00 49.95 ? 339 CYS B CB 1 ATOM 8368 S SG . CYS B 1 303 ? 56.356 97.408 83.491 1.00 62.49 ? 339 CYS B SG 1 ATOM 8369 N N . LEU B 1 304 ? 58.469 101.657 85.649 1.00 49.01 ? 340 LEU B N 1 ATOM 8370 C CA . LEU B 1 304 ? 59.416 102.766 85.580 1.00 52.16 ? 340 LEU B CA 1 ATOM 8371 C C . LEU B 1 304 ? 60.598 102.456 84.658 1.00 48.36 ? 340 LEU B C 1 ATOM 8372 O O . LEU B 1 304 ? 61.315 101.478 84.864 1.00 44.99 ? 340 LEU B O 1 ATOM 8373 C CB . LEU B 1 304 ? 59.915 103.147 86.979 1.00 50.14 ? 340 LEU B CB 1 ATOM 8374 C CG . LEU B 1 304 ? 58.946 103.938 87.858 1.00 51.78 ? 340 LEU B CG 1 ATOM 8375 N N . VAL B 1 305 ? 60.794 103.292 83.642 1.00 43.58 ? 341 VAL B N 1 ATOM 8376 C CA . VAL B 1 305 ? 61.904 103.125 82.702 1.00 45.40 ? 341 VAL B CA 1 ATOM 8377 C C . VAL B 1 305 ? 63.259 103.084 83.408 1.00 46.78 ? 341 VAL B C 1 ATOM 8378 O O . VAL B 1 305 ? 64.146 102.304 83.043 1.00 47.99 ? 341 VAL B O 1 ATOM 8379 C CB . VAL B 1 305 ? 61.931 104.262 81.647 1.00 46.18 ? 341 VAL B CB 1 ATOM 8380 C CG1 . VAL B 1 305 ? 63.095 104.068 80.679 1.00 45.26 ? 341 VAL B CG1 1 ATOM 8381 C CG2 . VAL B 1 305 ? 60.603 104.334 80.900 1.00 47.88 ? 341 VAL B CG2 1 ATOM 8382 N N . ALA B 1 306 ? 63.418 103.921 84.425 1.00 47.32 ? 342 ALA B N 1 ATOM 8383 C CA . ALA B 1 306 ? 64.689 104.026 85.129 1.00 47.96 ? 342 ALA B CA 1 ATOM 8384 C C . ALA B 1 306 ? 65.091 102.721 85.826 1.00 48.61 ? 342 ALA B C 1 ATOM 8385 O O . ALA B 1 306 ? 66.273 102.491 86.090 1.00 46.60 ? 342 ALA B O 1 ATOM 8386 C CB . ALA B 1 306 ? 64.646 105.181 86.127 1.00 47.72 ? 342 ALA B CB 1 ATOM 8387 N N . ARG B 1 307 ? 64.106 101.876 86.123 1.00 48.64 ? 343 ARG B N 1 ATOM 8388 C CA . ARG B 1 307 ? 64.348 100.564 86.740 1.00 46.15 ? 343 ARG B CA 1 ATOM 8389 C C . ARG B 1 307 ? 64.784 99.463 85.765 1.00 46.16 ? 343 ARG B C 1 ATOM 8390 O O . ARG B 1 307 ? 65.235 98.404 86.198 1.00 44.94 ? 343 ARG B O 1 ATOM 8391 C CB . ARG B 1 307 ? 63.094 100.077 87.447 1.00 47.40 ? 343 ARG B CB 1 ATOM 8392 C CG . ARG B 1 307 ? 62.822 100.774 88.734 1.00 50.41 ? 343 ARG B CG 1 ATOM 8393 C CD . ARG B 1 307 ? 61.674 100.121 89.445 1.00 47.43 ? 343 ARG B CD 1 ATOM 8394 N NE . ARG B 1 307 ? 61.542 100.665 90.789 1.00 55.64 ? 343 ARG B NE 1 ATOM 8395 C CZ . ARG B 1 307 ? 60.396 101.065 91.321 1.00 57.57 ? 343 ARG B CZ 1 ATOM 8396 N NH1 . ARG B 1 307 ? 59.268 100.986 90.613 1.00 55.56 ? 343 ARG B NH1 1 ATOM 8397 N NH2 . ARG B 1 307 ? 60.383 101.545 92.560 1.00 58.22 ? 343 ARG B NH2 1 ATOM 8398 N N . GLN B 1 308 ? 64.635 99.706 84.463 1.00 42.10 ? 344 GLN B N 1 ATOM 8399 C CA . GLN B 1 308 ? 64.967 98.703 83.458 1.00 39.91 ? 344 GLN B CA 1 ATOM 8400 C C . GLN B 1 308 ? 66.404 98.250 83.585 1.00 41.59 ? 344 GLN B C 1 ATOM 8401 O O . GLN B 1 308 ? 67.294 99.050 83.861 1.00 42.63 ? 344 GLN B O 1 ATOM 8402 C CB . GLN B 1 308 ? 64.778 99.261 82.051 1.00 40.47 ? 344 GLN B CB 1 ATOM 8403 C CG . GLN B 1 308 ? 63.361 99.566 81.658 1.00 41.43 ? 344 GLN B CG 1 ATOM 8404 C CD . GLN B 1 308 ? 63.282 100.059 80.227 1.00 44.16 ? 344 GLN B CD 1 ATOM 8405 O OE1 . GLN B 1 308 ? 64.290 100.077 79.510 1.00 44.60 ? 344 GLN B OE1 1 ATOM 8406 N NE2 . GLN B 1 308 ? 62.090 100.466 79.803 1.00 45.22 ? 344 GLN B NE2 1 ATOM 8407 N N . HIS B 1 309 ? 66.635 96.963 83.370 1.00 41.43 ? 345 HIS B N 1 ATOM 8408 C CA . HIS B 1 309 ? 67.993 96.441 83.310 1.00 39.15 ? 345 HIS B CA 1 ATOM 8409 C C . HIS B 1 309 ? 68.272 95.854 81.934 1.00 40.05 ? 345 HIS B C 1 ATOM 8410 O O . HIS B 1 309 ? 67.593 94.921 81.489 1.00 35.85 ? 345 HIS B O 1 ATOM 8411 C CB . HIS B 1 309 ? 68.241 95.421 84.416 1.00 37.24 ? 345 HIS B CB 1 ATOM 8412 C CG . HIS B 1 309 ? 68.443 96.046 85.763 1.00 45.60 ? 345 HIS B CG 1 ATOM 8413 N ND1 . HIS B 1 309 ? 69.642 96.611 86.147 1.00 49.53 ? 345 HIS B ND1 1 ATOM 8414 C CD2 . HIS B 1 309 ? 67.593 96.221 86.803 1.00 45.71 ? 345 HIS B CD2 1 ATOM 8415 C CE1 . HIS B 1 309 ? 69.524 97.097 87.371 1.00 48.65 ? 345 HIS B CE1 1 ATOM 8416 N NE2 . HIS B 1 309 ? 68.289 96.878 87.789 1.00 48.42 ? 345 HIS B NE2 1 ATOM 8417 N N . ILE B 1 310 ? 69.271 96.416 81.266 1.00 33.57 ? 346 ILE B N 1 ATOM 8418 C CA . ILE B 1 310 ? 69.571 96.048 79.904 1.00 35.48 ? 346 ILE B CA 1 ATOM 8419 C C . ILE B 1 310 ? 70.759 95.104 79.817 1.00 38.63 ? 346 ILE B C 1 ATOM 8420 O O . ILE B 1 310 ? 71.752 95.271 80.520 1.00 35.50 ? 346 ILE B O 1 ATOM 8421 C CB . ILE B 1 310 ? 69.832 97.293 79.058 1.00 38.60 ? 346 ILE B CB 1 ATOM 8422 C CG1 . ILE B 1 310 ? 68.542 98.125 78.957 1.00 41.32 ? 346 ILE B CG1 1 ATOM 8423 C CG2 . ILE B 1 310 ? 70.356 96.891 77.693 1.00 38.37 ? 346 ILE B CG2 1 ATOM 8424 C CD1 . ILE B 1 310 ? 68.730 99.531 78.424 1.00 44.22 ? 346 ILE B CD1 1 ATOM 8425 N N . GLU B 1 311 ? 70.643 94.103 78.950 1.00 36.30 ? 347 GLU B N 1 ATOM 8426 C CA . GLU B 1 311 ? 71.689 93.108 78.793 1.00 40.85 ? 347 GLU B CA 1 ATOM 8427 C C . GLU B 1 311 ? 72.000 92.969 77.305 1.00 43.52 ? 347 GLU B C 1 ATOM 8428 O O . GLU B 1 311 ? 71.111 92.701 76.497 1.00 43.83 ? 347 GLU B O 1 ATOM 8429 C CB . GLU B 1 311 ? 71.238 91.778 79.420 1.00 45.17 ? 347 GLU B CB 1 ATOM 8430 C CG . GLU B 1 311 ? 72.332 90.742 79.651 1.00 47.80 ? 347 GLU B CG 1 ATOM 8431 C CD . GLU B 1 311 ? 71.813 89.522 80.411 1.00 52.82 ? 347 GLU B CD 1 ATOM 8432 O OE1 . GLU B 1 311 ? 72.515 88.482 80.452 1.00 51.27 ? 347 GLU B OE1 1 ATOM 8433 O OE2 . GLU B 1 311 ? 70.697 89.604 80.970 1.00 51.54 ? 347 GLU B OE2 1 ATOM 8434 N N . MET B 1 312 ? 73.261 93.182 76.948 1.00 41.76 ? 348 MET B N 1 ATOM 8435 C CA . MET B 1 312 ? 73.690 93.167 75.561 1.00 42.46 ? 348 MET B CA 1 ATOM 8436 C C . MET B 1 312 ? 74.830 92.180 75.417 1.00 43.77 ? 348 MET B C 1 ATOM 8437 O O . MET B 1 312 ? 75.586 91.950 76.360 1.00 46.78 ? 348 MET B O 1 ATOM 8438 C CB . MET B 1 312 ? 74.220 94.544 75.150 1.00 45.40 ? 348 MET B CB 1 ATOM 8439 C CG . MET B 1 312 ? 73.266 95.694 75.349 1.00 49.92 ? 348 MET B CG 1 ATOM 8440 S SD . MET B 1 312 ? 73.968 97.249 74.742 1.00 66.50 ? 348 MET B SD 1 ATOM 8441 C CE . MET B 1 312 ? 75.465 97.374 75.724 1.00 57.48 ? 348 MET B CE 1 ATOM 8442 N N . SER B 1 313 ? 74.968 91.603 74.232 1.00 43.87 ? 349 SER B N 1 ATOM 8443 C CA . SER B 1 313 ? 76.161 90.840 73.917 1.00 45.94 ? 349 SER B CA 1 ATOM 8444 C C . SER B 1 313 ? 76.691 91.350 72.584 1.00 47.54 ? 349 SER B C 1 ATOM 8445 O O . SER B 1 313 ? 75.913 91.670 71.686 1.00 48.12 ? 349 SER B O 1 ATOM 8446 C CB . SER B 1 313 ? 75.841 89.339 73.869 1.00 44.28 ? 349 SER B CB 1 ATOM 8447 O OG . SER B 1 313 ? 77.003 88.557 73.623 1.00 44.41 ? 349 SER B OG 1 ATOM 8448 N N . THR B 1 314 ? 78.009 91.464 72.463 1.00 49.64 ? 350 THR B N 1 ATOM 8449 C CA . THR B 1 314 ? 78.619 91.801 71.175 1.00 52.99 ? 350 THR B CA 1 ATOM 8450 C C . THR B 1 314 ? 79.349 90.584 70.619 1.00 53.16 ? 350 THR B C 1 ATOM 8451 O O . THR B 1 314 ? 79.639 90.510 69.424 1.00 56.09 ? 350 THR B O 1 ATOM 8452 C CB . THR B 1 314 ? 79.608 92.982 71.286 1.00 61.78 ? 350 THR B CB 1 ATOM 8453 O OG1 . THR B 1 314 ? 80.020 93.137 72.651 1.00 63.65 ? 350 THR B OG1 1 ATOM 8454 C CG2 . THR B 1 314 ? 78.961 94.282 70.789 1.00 62.50 ? 350 THR B CG2 1 ATOM 8455 N N . THR B 1 315 ? 79.632 89.631 71.503 1.00 50.19 ? 351 THR B N 1 ATOM 8456 C CA . THR B 1 315 ? 80.304 88.391 71.137 1.00 50.47 ? 351 THR B CA 1 ATOM 8457 C C . THR B 1 315 ? 79.350 87.352 70.521 1.00 47.04 ? 351 THR B C 1 ATOM 8458 O O . THR B 1 315 ? 79.759 86.538 69.701 1.00 42.76 ? 351 THR B O 1 ATOM 8459 C CB . THR B 1 315 ? 80.988 87.772 72.368 1.00 51.35 ? 351 THR B CB 1 ATOM 8460 O OG1 . THR B 1 315 ? 81.930 88.708 72.908 1.00 62.39 ? 351 THR B OG1 1 ATOM 8461 C CG2 . THR B 1 315 ? 81.720 86.504 71.987 1.00 51.42 ? 351 THR B CG2 1 ATOM 8462 N N . GLY B 1 316 ? 78.081 87.375 70.929 1.00 43.47 ? 352 GLY B N 1 ATOM 8463 C CA . GLY B 1 316 ? 77.113 86.407 70.440 1.00 38.53 ? 352 GLY B CA 1 ATOM 8464 C C . GLY B 1 316 ? 75.692 86.759 70.831 1.00 36.93 ? 352 GLY B C 1 ATOM 8465 O O . GLY B 1 316 ? 75.276 87.902 70.693 1.00 39.11 ? 352 GLY B O 1 ATOM 8466 N N . TRP B 1 317 ? 74.947 85.770 71.312 1.00 32.20 ? 353 TRP B N 1 ATOM 8467 C CA . TRP B 1 317 ? 73.572 85.968 71.743 1.00 33.62 ? 353 TRP B CA 1 ATOM 8468 C C . TRP B 1 317 ? 73.523 86.196 73.267 1.00 30.47 ? 353 TRP B C 1 ATOM 8469 O O . TRP B 1 317 ? 74.543 86.124 73.942 1.00 33.70 ? 353 TRP B O 1 ATOM 8470 C CB . TRP B 1 317 ? 72.721 84.755 71.347 1.00 28.76 ? 353 TRP B CB 1 ATOM 8471 C CG . TRP B 1 317 ? 73.295 83.450 71.836 1.00 27.20 ? 353 TRP B CG 1 ATOM 8472 C CD1 . TRP B 1 317 ? 72.895 82.735 72.933 1.00 25.89 ? 353 TRP B CD1 1 ATOM 8473 C CD2 . TRP B 1 317 ? 74.376 82.713 71.250 1.00 28.16 ? 353 TRP B CD2 1 ATOM 8474 N NE1 . TRP B 1 317 ? 73.666 81.607 73.069 1.00 25.99 ? 353 TRP B NE1 1 ATOM 8475 C CE2 . TRP B 1 317 ? 74.584 81.571 72.050 1.00 30.72 ? 353 TRP B CE2 1 ATOM 8476 C CE3 . TRP B 1 317 ? 75.193 82.911 70.129 1.00 26.94 ? 353 TRP B CE3 1 ATOM 8477 C CZ2 . TRP B 1 317 ? 75.569 80.625 71.759 1.00 27.75 ? 353 TRP B CZ2 1 ATOM 8478 C CZ3 . TRP B 1 317 ? 76.165 81.968 69.838 1.00 29.25 ? 353 TRP B CZ3 1 ATOM 8479 C CH2 . TRP B 1 317 ? 76.344 80.837 70.650 1.00 28.20 ? 353 TRP B CH2 1 ATOM 8480 N N . VAL B 1 318 ? 72.340 86.473 73.803 1.00 29.68 ? 354 VAL B N 1 ATOM 8481 C CA . VAL B 1 318 ? 72.184 86.682 75.237 1.00 32.54 ? 354 VAL B CA 1 ATOM 8482 C C . VAL B 1 318 ? 71.780 85.403 75.961 1.00 33.70 ? 354 VAL B C 1 ATOM 8483 O O . VAL B 1 318 ? 70.767 84.787 75.612 1.00 30.34 ? 354 VAL B O 1 ATOM 8484 C CB . VAL B 1 318 ? 71.097 87.714 75.525 1.00 32.57 ? 354 VAL B CB 1 ATOM 8485 C CG1 . VAL B 1 318 ? 70.979 87.932 77.030 1.00 32.79 ? 354 VAL B CG1 1 ATOM 8486 C CG2 . VAL B 1 318 ? 71.407 89.012 74.796 1.00 36.60 ? 354 VAL B CG2 1 ATOM 8487 N N . GLY B 1 319 ? 72.559 85.014 76.973 1.00 30.98 ? 355 GLY B N 1 ATOM 8488 C CA . GLY B 1 319 ? 72.235 83.848 77.786 1.00 30.16 ? 355 GLY B CA 1 ATOM 8489 C C . GLY B 1 319 ? 72.732 82.573 77.134 1.00 29.02 ? 355 GLY B C 1 ATOM 8490 O O . GLY B 1 319 ? 73.191 82.624 75.997 1.00 31.09 ? 355 GLY B O 1 ATOM 8491 N N . ARG B 1 320 ? 72.653 81.430 77.815 1.00 25.85 ? 356 ARG B N 1 ATOM 8492 C CA . ARG B 1 320 ? 73.096 80.187 77.162 1.00 28.13 ? 356 ARG B CA 1 ATOM 8493 C C . ARG B 1 320 ? 72.175 79.831 75.993 1.00 30.73 ? 356 ARG B C 1 ATOM 8494 O O . ARG B 1 320 ? 72.639 79.614 74.860 1.00 31.03 ? 356 ARG B O 1 ATOM 8495 C CB . ARG B 1 320 ? 73.203 79.027 78.153 1.00 26.69 ? 356 ARG B CB 1 ATOM 8496 C CG . ARG B 1 320 ? 74.434 79.128 79.080 1.00 27.86 ? 356 ARG B CG 1 ATOM 8497 C CD . ARG B 1 320 ? 74.555 77.932 80.028 1.00 29.63 ? 356 ARG B CD 1 ATOM 8498 N NE . ARG B 1 320 ? 75.809 78.008 80.782 1.00 32.51 ? 356 ARG B NE 1 ATOM 8499 C CZ . ARG B 1 320 ? 75.904 78.358 82.063 1.00 31.49 ? 356 ARG B CZ 1 ATOM 8500 N NH1 . ARG B 1 320 ? 74.818 78.641 82.772 1.00 28.39 ? 356 ARG B NH1 1 ATOM 8501 N NH2 . ARG B 1 320 ? 77.094 78.409 82.641 1.00 31.35 ? 356 ARG B NH2 1 ATOM 8502 N N . PHE B 1 321 ? 70.878 79.771 76.286 1.00 27.46 ? 357 PHE B N 1 ATOM 8503 C CA . PHE B 1 321 ? 69.827 79.617 75.277 1.00 32.42 ? 357 PHE B CA 1 ATOM 8504 C C . PHE B 1 321 ? 68.857 80.810 75.277 1.00 32.99 ? 357 PHE B C 1 ATOM 8505 O O . PHE B 1 321 ? 68.108 81.017 74.324 1.00 36.50 ? 357 PHE B O 1 ATOM 8506 C CB . PHE B 1 321 ? 69.058 78.310 75.498 1.00 32.28 ? 357 PHE B CB 1 ATOM 8507 C CG . PHE B 1 321 ? 69.893 77.080 75.288 1.00 32.52 ? 357 PHE B CG 1 ATOM 8508 C CD1 . PHE B 1 321 ? 70.638 76.548 76.327 1.00 31.41 ? 357 PHE B CD1 1 ATOM 8509 C CD2 . PHE B 1 321 ? 69.955 76.473 74.045 1.00 33.34 ? 357 PHE B CD2 1 ATOM 8510 C CE1 . PHE B 1 321 ? 71.419 75.419 76.140 1.00 27.69 ? 357 PHE B CE1 1 ATOM 8511 C CE2 . PHE B 1 321 ? 70.725 75.338 73.845 1.00 31.26 ? 357 PHE B CE2 1 ATOM 8512 C CZ . PHE B 1 321 ? 71.463 74.812 74.890 1.00 32.60 ? 357 PHE B CZ 1 ATOM 8513 N N . ARG B 1 322 ? 68.880 81.589 76.353 1.00 31.09 ? 358 ARG B N 1 ATOM 8514 C CA . ARG B 1 322 ? 68.003 82.743 76.510 1.00 31.24 ? 358 ARG B CA 1 ATOM 8515 C C . ARG B 1 322 ? 68.460 83.516 77.744 1.00 30.93 ? 358 ARG B C 1 ATOM 8516 O O . ARG B 1 322 ? 69.254 83.001 78.532 1.00 28.70 ? 358 ARG B O 1 ATOM 8517 C CB . ARG B 1 322 ? 66.560 82.283 76.704 1.00 31.83 ? 358 ARG B CB 1 ATOM 8518 C CG . ARG B 1 322 ? 66.325 81.471 77.985 1.00 29.46 ? 358 ARG B CG 1 ATOM 8519 C CD . ARG B 1 322 ? 64.963 80.800 77.926 1.00 35.13 ? 358 ARG B CD 1 ATOM 8520 N NE . ARG B 1 322 ? 64.880 80.036 76.685 1.00 42.87 ? 358 ARG B NE 1 ATOM 8521 C CZ . ARG B 1 322 ? 65.164 78.744 76.591 1.00 40.84 ? 358 ARG B CZ 1 ATOM 8522 N NH1 . ARG B 1 322 ? 65.089 78.131 75.410 1.00 40.87 ? 358 ARG B NH1 1 ATOM 8523 N NH2 . ARG B 1 322 ? 65.522 78.072 77.679 1.00 40.83 ? 358 ARG B NH2 1 ATOM 8524 N N . PRO B 1 323 ? 67.966 84.750 77.928 1.00 29.59 ? 359 PRO B N 1 ATOM 8525 C CA . PRO B 1 323 ? 68.350 85.476 79.143 1.00 31.36 ? 359 PRO B CA 1 ATOM 8526 C C . PRO B 1 323 ? 68.062 84.648 80.399 1.00 30.58 ? 359 PRO B C 1 ATOM 8527 O O . PRO B 1 323 ? 67.043 83.982 80.454 1.00 27.00 ? 359 PRO B O 1 ATOM 8528 C CB . PRO B 1 323 ? 67.442 86.710 79.110 1.00 34.65 ? 359 PRO B CB 1 ATOM 8529 C CG . PRO B 1 323 ? 67.200 86.945 77.659 1.00 32.90 ? 359 PRO B CG 1 ATOM 8530 C CD . PRO B 1 323 ? 67.118 85.567 77.042 1.00 33.72 ? 359 PRO B CD 1 ATOM 8531 N N . SER B 1 324 ? 68.954 84.705 81.379 1.00 29.11 ? 360 SER B N 1 ATOM 8532 C CA . SER B 1 324 ? 68.816 83.947 82.614 1.00 32.35 ? 360 SER B CA 1 ATOM 8533 C C . SER B 1 324 ? 67.681 84.454 83.503 1.00 30.09 ? 360 SER B C 1 ATOM 8534 O O . SER B 1 324 ? 67.268 85.606 83.414 1.00 33.19 ? 360 SER B O 1 ATOM 8535 C CB . SER B 1 324 ? 70.137 83.971 83.380 1.00 32.71 ? 360 SER B CB 1 ATOM 8536 O OG . SER B 1 324 ? 70.523 85.309 83.682 1.00 31.65 ? 360 SER B OG 1 ATOM 8537 N N . GLU B 1 325 ? 67.176 83.561 84.345 1.00 31.04 ? 361 GLU B N 1 ATOM 8538 C CA . GLU B 1 325 ? 66.130 83.852 85.315 1.00 33.70 ? 361 GLU B CA 1 ATOM 8539 C C . GLU B 1 325 ? 66.666 84.673 86.494 1.00 31.03 ? 361 GLU B C 1 ATOM 8540 O O . GLU B 1 325 ? 67.752 84.406 86.991 1.00 29.12 ? 361 GLU B O 1 ATOM 8541 C CB . GLU B 1 325 ? 65.571 82.531 85.844 1.00 36.16 ? 361 GLU B CB 1 ATOM 8542 C CG . GLU B 1 325 ? 64.540 82.668 86.944 1.00 41.43 ? 361 GLU B CG 1 ATOM 8543 C CD . GLU B 1 325 ? 64.030 81.311 87.422 1.00 55.10 ? 361 GLU B CD 1 ATOM 8544 O OE1 . GLU B 1 325 ? 64.619 80.288 86.992 1.00 55.42 ? 361 GLU B OE1 1 ATOM 8545 O OE2 . GLU B 1 325 ? 63.048 81.271 88.213 1.00 54.13 ? 361 GLU B OE2 1 ATOM 8546 N N . PRO B 1 326 ? 65.896 85.670 86.945 1.00 33.11 ? 362 PRO B N 1 ATOM 8547 C CA . PRO B 1 326 ? 66.278 86.464 88.116 1.00 29.93 ? 362 PRO B CA 1 ATOM 8548 C C . PRO B 1 326 ? 65.799 85.787 89.390 1.00 30.26 ? 362 PRO B C 1 ATOM 8549 O O . PRO B 1 326 ? 64.665 85.336 89.429 1.00 31.70 ? 362 PRO B O 1 ATOM 8550 C CB . PRO B 1 326 ? 65.479 87.744 87.922 1.00 32.67 ? 362 PRO B CB 1 ATOM 8551 C CG . PRO B 1 326 ? 64.220 87.278 87.279 1.00 35.90 ? 362 PRO B CG 1 ATOM 8552 C CD . PRO B 1 326 ? 64.624 86.137 86.360 1.00 33.50 ? 362 PRO B CD 1 ATOM 8553 N N . HIS B 1 327 ? 66.633 85.747 90.420 1.00 30.63 ? 363 HIS B N 1 ATOM 8554 C CA . HIS B 1 327 ? 66.220 85.210 91.714 1.00 28.14 ? 363 HIS B CA 1 ATOM 8555 C C . HIS B 1 327 ? 66.124 86.297 92.787 1.00 27.19 ? 363 HIS B C 1 ATOM 8556 O O . HIS B 1 327 ? 67.130 86.774 93.303 1.00 24.20 ? 363 HIS B O 1 ATOM 8557 C CB . HIS B 1 327 ? 67.187 84.115 92.152 1.00 29.30 ? 363 HIS B CB 1 ATOM 8558 C CG . HIS B 1 327 ? 67.206 82.938 91.228 1.00 32.60 ? 363 HIS B CG 1 ATOM 8559 N ND1 . HIS B 1 327 ? 66.629 81.729 91.553 1.00 31.44 ? 363 HIS B ND1 1 ATOM 8560 C CD2 . HIS B 1 327 ? 67.716 82.790 89.982 1.00 29.16 ? 363 HIS B CD2 1 ATOM 8561 C CE1 . HIS B 1 327 ? 66.787 80.885 90.547 1.00 37.97 ? 363 HIS B CE1 1 ATOM 8562 N NE2 . HIS B 1 327 ? 67.443 81.503 89.580 1.00 31.92 ? 363 HIS B NE2 1 ATOM 8563 N N . PHE B 1 328 ? 64.900 86.669 93.126 1.00 26.40 ? 364 PHE B N 1 ATOM 8564 C CA . PHE B 1 328 ? 64.660 87.787 94.026 1.00 31.12 ? 364 PHE B CA 1 ATOM 8565 C C . PHE B 1 328 ? 64.838 87.459 95.495 1.00 31.71 ? 364 PHE B C 1 ATOM 8566 O O . PHE B 1 328 ? 64.442 86.398 95.955 1.00 30.25 ? 364 PHE B O 1 ATOM 8567 C CB . PHE B 1 328 ? 63.250 88.328 93.818 1.00 29.14 ? 364 PHE B CB 1 ATOM 8568 C CG . PHE B 1 328 ? 63.111 89.150 92.582 1.00 30.95 ? 364 PHE B CG 1 ATOM 8569 C CD1 . PHE B 1 328 ? 62.869 88.549 91.362 1.00 33.50 ? 364 PHE B CD1 1 ATOM 8570 C CD2 . PHE B 1 328 ? 63.251 90.523 92.637 1.00 29.20 ? 364 PHE B CD2 1 ATOM 8571 C CE1 . PHE B 1 328 ? 62.752 89.309 90.215 1.00 33.38 ? 364 PHE B CE1 1 ATOM 8572 C CE2 . PHE B 1 328 ? 63.131 91.284 91.503 1.00 33.71 ? 364 PHE B CE2 1 ATOM 8573 C CZ . PHE B 1 328 ? 62.882 90.677 90.286 1.00 29.89 ? 364 PHE B CZ 1 ATOM 8574 N N . THR B 1 329 ? 65.425 88.396 96.223 1.00 32.22 ? 365 THR B N 1 ATOM 8575 C CA . THR B 1 329 ? 65.413 88.347 97.677 1.00 35.46 ? 365 THR B CA 1 ATOM 8576 C C . THR B 1 329 ? 63.971 88.435 98.169 1.00 35.96 ? 365 THR B C 1 ATOM 8577 O O . THR B 1 329 ? 63.057 88.768 97.409 1.00 37.31 ? 365 THR B O 1 ATOM 8578 C CB . THR B 1 329 ? 66.159 89.521 98.240 1.00 36.41 ? 365 THR B CB 1 ATOM 8579 O OG1 . THR B 1 329 ? 65.515 90.716 97.781 1.00 37.31 ? 365 THR B OG1 1 ATOM 8580 C CG2 . THR B 1 329 ? 67.596 89.495 97.757 1.00 31.93 ? 365 THR B CG2 1 ATOM 8581 N N . LEU B 1 330 ? 63.767 88.123 99.443 1.00 38.16 ? 366 LEU B N 1 ATOM 8582 C CA . LEU B 1 330 ? 62.428 88.080 100.022 1.00 39.68 ? 366 LEU B CA 1 ATOM 8583 C C . LEU B 1 330 ? 61.628 89.371 99.833 1.00 36.43 ? 366 LEU B C 1 ATOM 8584 O O . LEU B 1 330 ? 60.421 89.323 99.588 1.00 36.02 ? 366 LEU B O 1 ATOM 8585 C CB . LEU B 1 330 ? 62.507 87.728 101.510 1.00 43.18 ? 366 LEU B CB 1 ATOM 8586 C CG . LEU B 1 330 ? 61.172 87.707 102.253 1.00 45.02 ? 366 LEU B CG 1 ATOM 8587 C CD1 . LEU B 1 330 ? 60.196 86.792 101.542 1.00 42.61 ? 366 LEU B CD1 1 ATOM 8588 C CD2 . LEU B 1 330 ? 61.362 87.272 103.714 1.00 40.49 ? 366 LEU B CD2 1 ATOM 8589 N N . ASP B 1 331 ? 62.292 90.518 99.942 1.00 39.54 ? 367 ASP B N 1 ATOM 8590 C CA . ASP B 1 331 ? 61.587 91.811 99.865 1.00 41.55 ? 367 ASP B CA 1 ATOM 8591 C C . ASP B 1 331 ? 61.332 92.324 98.446 1.00 41.79 ? 367 ASP B C 1 ATOM 8592 O O . ASP B 1 331 ? 60.686 93.358 98.255 1.00 39.84 ? 367 ASP B O 1 ATOM 8593 C CB . ASP B 1 331 ? 62.272 92.888 100.721 1.00 41.82 ? 367 ASP B CB 1 ATOM 8594 C CG . ASP B 1 331 ? 63.691 93.236 100.248 1.00 44.02 ? 367 ASP B CG 1 ATOM 8595 O OD1 . ASP B 1 331 ? 64.061 92.910 99.094 1.00 43.39 ? 367 ASP B OD1 1 ATOM 8596 O OD2 . ASP B 1 331 ? 64.436 93.871 101.041 1.00 43.35 ? 367 ASP B OD2 1 ATOM 8597 N N . GLY B 1 332 ? 61.826 91.594 97.452 1.00 37.49 ? 368 GLY B N 1 ATOM 8598 C CA . GLY B 1 332 ? 61.610 91.958 96.066 1.00 35.08 ? 368 GLY B CA 1 ATOM 8599 C C . GLY B 1 332 ? 62.410 93.161 95.590 1.00 38.76 ? 368 GLY B C 1 ATOM 8600 O O . GLY B 1 332 ? 62.201 93.647 94.479 1.00 36.57 ? 368 GLY B O 1 ATOM 8601 N N . ASN B 1 333 ? 63.337 93.627 96.419 1.00 39.34 ? 369 ASN B N 1 ATOM 8602 C CA . ASN B 1 333 ? 64.087 94.851 96.135 1.00 38.42 ? 369 ASN B CA 1 ATOM 8603 C C . ASN B 1 333 ? 65.443 94.646 95.493 1.00 37.95 ? 369 ASN B C 1 ATOM 8604 O O . ASN B 1 333 ? 66.060 95.607 95.027 1.00 34.69 ? 369 ASN B O 1 ATOM 8605 C CB . ASN B 1 333 ? 64.281 95.650 97.417 1.00 43.10 ? 369 ASN B CB 1 ATOM 8606 C CG . ASN B 1 333 ? 63.328 96.804 97.519 1.00 50.78 ? 369 ASN B CG 1 ATOM 8607 O OD1 . ASN B 1 333 ? 63.176 97.585 96.565 1.00 57.77 ? 369 ASN B OD1 1 ATOM 8608 N ND2 . ASN B 1 333 ? 62.658 96.920 98.665 1.00 50.08 ? 369 ASN B ND2 1 ATOM 8609 N N . SER B 1 334 ? 65.915 93.401 95.498 1.00 30.96 ? 370 SER B N 1 ATOM 8610 C CA . SER B 1 334 ? 67.166 93.045 94.854 1.00 31.90 ? 370 SER B CA 1 ATOM 8611 C C . SER B 1 334 ? 67.036 91.630 94.327 1.00 32.23 ? 370 SER B C 1 ATOM 8612 O O . SER B 1 334 ? 66.086 90.920 94.672 1.00 32.97 ? 370 SER B O 1 ATOM 8613 C CB . SER B 1 334 ? 68.324 93.136 95.838 1.00 32.90 ? 370 SER B CB 1 ATOM 8614 O OG . SER B 1 334 ? 68.026 92.404 97.010 1.00 34.92 ? 370 SER B OG 1 ATOM 8615 N N . PHE B 1 335 ? 67.974 91.225 93.480 1.00 30.94 ? 371 PHE B N 1 ATOM 8616 C CA . PHE B 1 335 ? 67.911 89.893 92.884 1.00 29.60 ? 371 PHE B CA 1 ATOM 8617 C C . PHE B 1 335 ? 69.270 89.415 92.446 1.00 27.50 ? 371 PHE B C 1 ATOM 8618 O O . PHE B 1 335 ? 70.203 90.201 92.354 1.00 30.06 ? 371 PHE B O 1 ATOM 8619 C CB . PHE B 1 335 ? 66.891 89.817 91.740 1.00 28.00 ? 371 PHE B CB 1 ATOM 8620 C CG . PHE B 1 335 ? 67.179 90.744 90.573 1.00 27.24 ? 371 PHE B CG 1 ATOM 8621 C CD1 . PHE B 1 335 ? 67.929 90.309 89.492 1.00 28.94 ? 371 PHE B CD1 1 ATOM 8622 C CD2 . PHE B 1 335 ? 66.653 92.031 90.540 1.00 33.46 ? 371 PHE B CD2 1 ATOM 8623 C CE1 . PHE B 1 335 ? 68.187 91.164 88.405 1.00 32.03 ? 371 PHE B CE1 1 ATOM 8624 C CE2 . PHE B 1 335 ? 66.892 92.887 89.453 1.00 32.16 ? 371 PHE B CE2 1 ATOM 8625 C CZ . PHE B 1 335 ? 67.659 92.451 88.390 1.00 32.31 ? 371 PHE B CZ 1 ATOM 8626 N N . TYR B 1 336 ? 69.386 88.113 92.217 1.00 24.86 ? 372 TYR B N 1 ATOM 8627 C CA . TYR B 1 336 ? 70.632 87.542 91.726 1.00 27.28 ? 372 TYR B CA 1 ATOM 8628 C C . TYR B 1 336 ? 70.373 86.915 90.346 1.00 26.09 ? 372 TYR B C 1 ATOM 8629 O O . TYR B 1 336 ? 69.281 86.411 90.076 1.00 27.20 ? 372 TYR B O 1 ATOM 8630 C CB . TYR B 1 336 ? 71.162 86.497 92.715 1.00 27.14 ? 372 TYR B CB 1 ATOM 8631 C CG . TYR B 1 336 ? 71.486 87.059 94.079 1.00 26.14 ? 372 TYR B CG 1 ATOM 8632 C CD1 . TYR B 1 336 ? 70.489 87.270 95.019 1.00 26.44 ? 372 TYR B CD1 1 ATOM 8633 C CD2 . TYR B 1 336 ? 72.785 87.400 94.413 1.00 23.90 ? 372 TYR B CD2 1 ATOM 8634 C CE1 . TYR B 1 336 ? 70.775 87.798 96.261 1.00 25.37 ? 372 TYR B CE1 1 ATOM 8635 C CE2 . TYR B 1 336 ? 73.086 87.916 95.658 1.00 28.24 ? 372 TYR B CE2 1 ATOM 8636 C CZ . TYR B 1 336 ? 72.078 88.108 96.576 1.00 27.05 ? 372 TYR B CZ 1 ATOM 8637 O OH . TYR B 1 336 ? 72.378 88.630 97.809 1.00 31.95 ? 372 TYR B OH 1 ATOM 8638 N N . LYS B 1 337 ? 71.370 86.951 89.475 1.00 25.22 ? 373 LYS B N 1 ATOM 8639 C CA . LYS B 1 337 ? 71.172 86.512 88.105 1.00 29.99 ? 373 LYS B CA 1 ATOM 8640 C C . LYS B 1 337 ? 72.523 86.065 87.592 1.00 29.14 ? 373 LYS B C 1 ATOM 8641 O O . LYS B 1 337 ? 73.537 86.683 87.926 1.00 30.32 ? 373 LYS B O 1 ATOM 8642 C CB . LYS B 1 337 ? 70.676 87.711 87.294 1.00 34.18 ? 373 LYS B CB 1 ATOM 8643 C CG . LYS B 1 337 ? 69.966 87.424 86.020 1.00 33.48 ? 373 LYS B CG 1 ATOM 8644 C CD . LYS B 1 337 ? 69.544 88.753 85.378 1.00 35.44 ? 373 LYS B CD 1 ATOM 8645 C CE . LYS B 1 337 ? 68.515 88.569 84.295 1.00 36.83 ? 373 LYS B CE 1 ATOM 8646 N NZ . LYS B 1 337 ? 69.070 87.911 83.086 1.00 40.46 ? 373 LYS B NZ 1 ATOM 8647 N N . ILE B 1 338 ? 72.552 84.991 86.806 1.00 25.20 ? 374 ILE B N 1 ATOM 8648 C CA . ILE B 1 338 ? 73.784 84.570 86.124 1.00 28.22 ? 374 ILE B CA 1 ATOM 8649 C C . ILE B 1 338 ? 74.044 85.443 84.869 1.00 30.50 ? 374 ILE B C 1 ATOM 8650 O O . ILE B 1 338 ? 73.144 85.680 84.072 1.00 28.25 ? 374 ILE B O 1 ATOM 8651 C CB . ILE B 1 338 ? 73.723 83.085 85.690 1.00 27.62 ? 374 ILE B CB 1 ATOM 8652 C CG1 . ILE B 1 338 ? 73.646 82.164 86.909 1.00 25.38 ? 374 ILE B CG1 1 ATOM 8653 C CG2 . ILE B 1 338 ? 74.927 82.730 84.857 1.00 26.93 ? 374 ILE B CG2 1 ATOM 8654 C CD1 . ILE B 1 338 ? 73.258 80.768 86.566 1.00 28.45 ? 374 ILE B CD1 1 ATOM 8655 N N . ILE B 1 339 ? 75.277 85.913 84.712 1.00 28.82 ? 375 ILE B N 1 ATOM 8656 C CA . ILE B 1 339 ? 75.630 86.884 83.680 1.00 31.91 ? 375 ILE B CA 1 ATOM 8657 C C . ILE B 1 339 ? 77.034 86.545 83.215 1.00 30.93 ? 375 ILE B C 1 ATOM 8658 O O . ILE B 1 339 ? 77.882 86.201 84.031 1.00 29.51 ? 375 ILE B O 1 ATOM 8659 C CB . ILE B 1 339 ? 75.634 88.334 84.261 1.00 33.96 ? 375 ILE B CB 1 ATOM 8660 C CG1 . ILE B 1 339 ? 74.229 88.741 84.694 1.00 35.25 ? 375 ILE B CG1 1 ATOM 8661 C CG2 . ILE B 1 339 ? 76.158 89.348 83.243 1.00 34.86 ? 375 ILE B CG2 1 ATOM 8662 C CD1 . ILE B 1 339 ? 73.228 88.730 83.565 1.00 35.30 ? 375 ILE B CD1 1 ATOM 8663 N N . SER B 1 340 ? 77.290 86.623 81.915 1.00 29.26 ? 376 SER B N 1 ATOM 8664 C CA . SER B 1 340 ? 78.650 86.445 81.435 1.00 29.48 ? 376 SER B CA 1 ATOM 8665 C C . SER B 1 340 ? 79.534 87.603 81.916 1.00 33.54 ? 376 SER B C 1 ATOM 8666 O O . SER B 1 340 ? 79.214 88.760 81.659 1.00 36.12 ? 376 SER B O 1 ATOM 8667 C CB . SER B 1 340 ? 78.651 86.379 79.911 1.00 33.87 ? 376 SER B CB 1 ATOM 8668 O OG . SER B 1 340 ? 79.944 86.084 79.436 1.00 39.58 ? 376 SER B OG 1 ATOM 8669 N N . ASN B 1 341 ? 80.638 87.310 82.606 1.00 36.93 ? 377 ASN B N 1 ATOM 8670 C CA . ASN B 1 341 ? 81.519 88.386 83.108 1.00 34.96 ? 377 ASN B CA 1 ATOM 8671 C C . ASN B 1 341 ? 82.450 88.951 82.031 1.00 39.60 ? 377 ASN B C 1 ATOM 8672 O O . ASN B 1 341 ? 82.327 88.600 80.859 1.00 38.53 ? 377 ASN B O 1 ATOM 8673 C CB . ASN B 1 341 ? 82.303 87.959 84.364 1.00 31.84 ? 377 ASN B CB 1 ATOM 8674 C CG . ASN B 1 341 ? 83.418 86.962 84.072 1.00 33.83 ? 377 ASN B CG 1 ATOM 8675 O OD1 . ASN B 1 341 ? 83.787 86.739 82.924 1.00 35.52 ? 377 ASN B OD1 1 ATOM 8676 N ND2 . ASN B 1 341 ? 83.968 86.363 85.130 1.00 34.68 ? 377 ASN B ND2 1 ATOM 8677 N N . GLU B 1 342 ? 83.377 89.823 82.421 1.00 38.57 ? 378 GLU B N 1 ATOM 8678 C CA . GLU B 1 342 ? 84.266 90.467 81.455 1.00 41.61 ? 378 GLU B CA 1 ATOM 8679 C C . GLU B 1 342 ? 85.205 89.487 80.757 1.00 43.58 ? 378 GLU B C 1 ATOM 8680 O O . GLU B 1 342 ? 85.599 89.724 79.623 1.00 42.37 ? 378 GLU B O 1 ATOM 8681 C CB . GLU B 1 342 ? 85.076 91.587 82.110 1.00 52.27 ? 378 GLU B CB 1 ATOM 8682 C CG . GLU B 1 342 ? 84.256 92.822 82.511 1.00 61.22 ? 378 GLU B CG 1 ATOM 8683 C CD . GLU B 1 342 ? 83.605 93.519 81.317 1.00 71.35 ? 378 GLU B CD 1 ATOM 8684 O OE1 . GLU B 1 342 ? 84.161 94.534 80.833 1.00 77.39 ? 378 GLU B OE1 1 ATOM 8685 O OE2 . GLU B 1 342 ? 82.532 93.052 80.867 1.00 71.76 ? 378 GLU B OE2 1 ATOM 8686 N N . GLU B 1 343 ? 85.568 88.394 81.430 1.00 40.67 ? 379 GLU B N 1 ATOM 8687 C CA . GLU B 1 343 ? 86.405 87.360 80.817 1.00 37.59 ? 379 GLU B CA 1 ATOM 8688 C C . GLU B 1 343 ? 85.599 86.331 80.023 1.00 39.43 ? 379 GLU B C 1 ATOM 8689 O O . GLU B 1 343 ? 86.158 85.372 79.494 1.00 32.61 ? 379 GLU B O 1 ATOM 8690 C CB . GLU B 1 343 ? 87.258 86.645 81.871 1.00 44.71 ? 379 GLU B CB 1 ATOM 8691 C CG . GLU B 1 343 ? 88.466 87.445 82.355 1.00 48.95 ? 379 GLU B CG 1 ATOM 8692 C CD . GLU B 1 343 ? 88.070 88.629 83.229 1.00 56.19 ? 379 GLU B CD 1 ATOM 8693 O OE1 . GLU B 1 343 ? 87.258 88.441 84.165 1.00 54.17 ? 379 GLU B OE1 1 ATOM 8694 O OE2 . GLU B 1 343 ? 88.566 89.752 82.980 1.00 63.00 ? 379 GLU B OE2 1 ATOM 8695 N N . GLY B 1 344 ? 84.285 86.528 79.950 1.00 38.62 ? 380 GLY B N 1 ATOM 8696 C CA . GLY B 1 344 ? 83.415 85.627 79.211 1.00 38.30 ? 380 GLY B CA 1 ATOM 8697 C C . GLY B 1 344 ? 82.934 84.398 79.979 1.00 36.63 ? 380 GLY B C 1 ATOM 8698 O O . GLY B 1 344 ? 82.445 83.453 79.370 1.00 36.18 ? 380 GLY B O 1 ATOM 8699 N N . TYR B 1 345 ? 83.062 84.396 81.303 1.00 31.62 ? 381 TYR B N 1 ATOM 8700 C CA . TYR B 1 345 ? 82.578 83.267 82.104 1.00 29.36 ? 381 TYR B CA 1 ATOM 8701 C C . TYR B 1 345 ? 81.310 83.616 82.876 1.00 32.43 ? 381 TYR B C 1 ATOM 8702 O O . TYR B 1 345 ? 81.203 84.704 83.456 1.00 31.90 ? 381 TYR B O 1 ATOM 8703 C CB . TYR B 1 345 ? 83.657 82.770 83.068 1.00 31.48 ? 381 TYR B CB 1 ATOM 8704 C CG . TYR B 1 345 ? 84.822 82.078 82.392 1.00 32.68 ? 381 TYR B CG 1 ATOM 8705 C CD1 . TYR B 1 345 ? 85.876 82.814 81.851 1.00 35.96 ? 381 TYR B CD1 1 ATOM 8706 C CD2 . TYR B 1 345 ? 84.877 80.689 82.298 1.00 32.39 ? 381 TYR B CD2 1 ATOM 8707 C CE1 . TYR B 1 345 ? 86.955 82.190 81.223 1.00 31.77 ? 381 TYR B CE1 1 ATOM 8708 C CE2 . TYR B 1 345 ? 85.961 80.049 81.679 1.00 28.53 ? 381 TYR B CE2 1 ATOM 8709 C CZ . TYR B 1 345 ? 86.993 80.810 81.149 1.00 34.84 ? 381 TYR B CZ 1 ATOM 8710 O OH . TYR B 1 345 ? 88.068 80.197 80.540 1.00 32.81 ? 381 TYR B OH 1 ATOM 8711 N N . ARG B 1 346 ? 80.355 82.687 82.894 1.00 29.67 ? 382 ARG B N 1 ATOM 8712 C CA . ARG B 1 346 ? 79.054 82.941 83.506 1.00 28.43 ? 382 ARG B CA 1 ATOM 8713 C C . ARG B 1 346 ? 79.090 82.814 85.029 1.00 29.73 ? 382 ARG B C 1 ATOM 8714 O O . ARG B 1 346 ? 79.349 81.742 85.587 1.00 26.59 ? 382 ARG B O 1 ATOM 8715 C CB . ARG B 1 346 ? 77.977 82.047 82.882 1.00 28.72 ? 382 ARG B CB 1 ATOM 8716 C CG . ARG B 1 346 ? 77.510 82.605 81.542 1.00 32.46 ? 382 ARG B CG 1 ATOM 8717 C CD . ARG B 1 346 ? 76.960 81.582 80.536 1.00 33.84 ? 382 ARG B CD 1 ATOM 8718 N NE . ARG B 1 346 ? 77.276 82.070 79.192 1.00 34.99 ? 382 ARG B NE 1 ATOM 8719 C CZ . ARG B 1 346 ? 76.573 82.998 78.550 1.00 30.42 ? 382 ARG B CZ 1 ATOM 8720 N NH1 . ARG B 1 346 ? 75.472 83.503 79.099 1.00 30.97 ? 382 ARG B NH1 1 ATOM 8721 N NH2 . ARG B 1 346 ? 76.973 83.417 77.364 1.00 30.24 ? 382 ARG B NH2 1 ATOM 8722 N N . HIS B 1 347 ? 78.829 83.927 85.698 1.00 28.56 ? 383 HIS B N 1 ATOM 8723 C CA . HIS B 1 347 ? 78.892 83.955 87.152 1.00 30.90 ? 383 HIS B CA 1 ATOM 8724 C C . HIS B 1 347 ? 77.707 84.681 87.759 1.00 25.67 ? 383 HIS B C 1 ATOM 8725 O O . HIS B 1 347 ? 76.898 85.265 87.046 1.00 28.44 ? 383 HIS B O 1 ATOM 8726 C CB . HIS B 1 347 ? 80.217 84.560 87.606 1.00 30.89 ? 383 HIS B CB 1 ATOM 8727 C CG . HIS B 1 347 ? 81.330 83.567 87.633 1.00 30.85 ? 383 HIS B CG 1 ATOM 8728 N ND1 . HIS B 1 347 ? 82.287 83.490 86.645 1.00 32.54 ? 383 HIS B ND1 1 ATOM 8729 C CD2 . HIS B 1 347 ? 81.604 82.570 88.504 1.00 26.83 ? 383 HIS B CD2 1 ATOM 8730 C CE1 . HIS B 1 347 ? 83.121 82.504 86.924 1.00 31.26 ? 383 HIS B CE1 1 ATOM 8731 N NE2 . HIS B 1 347 ? 82.726 81.929 88.046 1.00 30.53 ? 383 HIS B NE2 1 ATOM 8732 N N . ILE B 1 348 ? 77.607 84.635 89.079 1.00 30.57 ? 384 ILE B N 1 ATOM 8733 C CA . ILE B 1 348 ? 76.442 85.179 89.760 1.00 30.92 ? 384 ILE B CA 1 ATOM 8734 C C . ILE B 1 348 ? 76.617 86.654 90.059 1.00 30.24 ? 384 ILE B C 1 ATOM 8735 O O . ILE B 1 348 ? 77.621 87.067 90.638 1.00 32.02 ? 384 ILE B O 1 ATOM 8736 C CB . ILE B 1 348 ? 76.166 84.446 91.063 1.00 28.14 ? 384 ILE B CB 1 ATOM 8737 C CG1 . ILE B 1 348 ? 75.892 82.973 90.774 1.00 29.99 ? 384 ILE B CG1 1 ATOM 8738 C CG2 . ILE B 1 348 ? 74.992 85.089 91.769 1.00 27.91 ? 384 ILE B CG2 1 ATOM 8739 C CD1 . ILE B 1 348 ? 75.967 82.068 91.999 1.00 31.16 ? 384 ILE B CD1 1 ATOM 8740 N N . CYS B 1 349 ? 75.619 87.430 89.668 1.00 28.49 ? 385 CYS B N 1 ATOM 8741 C CA . CYS B 1 349 ? 75.656 88.870 89.758 1.00 26.28 ? 385 CYS B CA 1 ATOM 8742 C C . CYS B 1 349 ? 74.528 89.374 90.652 1.00 30.25 ? 385 CYS B C 1 ATOM 8743 O O . CYS B 1 349 ? 73.381 88.948 90.521 1.00 28.97 ? 385 CYS B O 1 ATOM 8744 C CB . CYS B 1 349 ? 75.468 89.432 88.356 1.00 36.05 ? 385 CYS B CB 1 ATOM 8745 S SG . CYS B 1 349 ? 76.347 90.948 88.072 1.00 46.44 ? 385 CYS B SG 1 ATOM 8746 N N . TYR B 1 350 ? 74.851 90.290 91.555 1.00 31.65 ? 386 TYR B N 1 ATOM 8747 C CA . TYR B 1 350 ? 73.871 90.818 92.510 1.00 27.96 ? 386 TYR B CA 1 ATOM 8748 C C . TYR B 1 350 ? 73.361 92.174 92.033 1.00 30.62 ? 386 TYR B C 1 ATOM 8749 O O . TYR B 1 350 ? 74.152 93.098 91.846 1.00 25.75 ? 386 TYR B O 1 ATOM 8750 C CB . TYR B 1 350 ? 74.532 90.951 93.886 1.00 29.63 ? 386 TYR B CB 1 ATOM 8751 C CG . TYR B 1 350 ? 73.703 91.639 94.950 1.00 26.10 ? 386 TYR B CG 1 ATOM 8752 C CD1 . TYR B 1 350 ? 72.396 91.242 95.216 1.00 26.65 ? 386 TYR B CD1 1 ATOM 8753 C CD2 . TYR B 1 350 ? 74.235 92.668 95.699 1.00 27.46 ? 386 TYR B CD2 1 ATOM 8754 C CE1 . TYR B 1 350 ? 71.638 91.879 96.201 1.00 29.90 ? 386 TYR B CE1 1 ATOM 8755 C CE2 . TYR B 1 350 ? 73.493 93.302 96.678 1.00 27.03 ? 386 TYR B CE2 1 ATOM 8756 C CZ . TYR B 1 350 ? 72.200 92.910 96.924 1.00 27.32 ? 386 TYR B CZ 1 ATOM 8757 O OH . TYR B 1 350 ? 71.466 93.549 97.907 1.00 34.40 ? 386 TYR B OH 1 ATOM 8758 N N . PHE B 1 351 ? 72.047 92.286 91.835 1.00 28.73 ? 387 PHE B N 1 ATOM 8759 C CA . PHE B 1 351 ? 71.428 93.499 91.300 1.00 28.24 ? 387 PHE B CA 1 ATOM 8760 C C . PHE B 1 351 ? 70.552 94.116 92.369 1.00 35.22 ? 387 PHE B C 1 ATOM 8761 O O . PHE B 1 351 ? 69.768 93.418 93.021 1.00 32.47 ? 387 PHE B O 1 ATOM 8762 C CB . PHE B 1 351 ? 70.495 93.182 90.134 1.00 30.05 ? 387 PHE B CB 1 ATOM 8763 C CG . PHE B 1 351 ? 71.195 92.810 88.857 1.00 36.39 ? 387 PHE B CG 1 ATOM 8764 C CD1 . PHE B 1 351 ? 71.748 91.551 88.697 1.00 28.25 ? 387 PHE B CD1 1 ATOM 8765 C CD2 . PHE B 1 351 ? 71.262 93.714 87.804 1.00 36.19 ? 387 PHE B CD2 1 ATOM 8766 C CE1 . PHE B 1 351 ? 72.380 91.199 87.516 1.00 34.19 ? 387 PHE B CE1 1 ATOM 8767 C CE2 . PHE B 1 351 ? 71.892 93.370 86.615 1.00 40.76 ? 387 PHE B CE2 1 ATOM 8768 C CZ . PHE B 1 351 ? 72.455 92.113 86.470 1.00 39.58 ? 387 PHE B CZ 1 ATOM 8769 N N . GLN B 1 352 ? 70.649 95.427 92.519 1.00 31.34 ? 388 GLN B N 1 ATOM 8770 C CA . GLN B 1 352 ? 69.734 96.144 93.389 1.00 33.86 ? 388 GLN B CA 1 ATOM 8771 C C . GLN B 1 352 ? 68.806 97.020 92.552 1.00 33.59 ? 388 GLN B C 1 ATOM 8772 O O . GLN B 1 352 ? 69.272 97.763 91.696 1.00 37.44 ? 388 GLN B O 1 ATOM 8773 C CB . GLN B 1 352 ? 70.528 96.961 94.411 1.00 30.44 ? 388 GLN B CB 1 ATOM 8774 C CG . GLN B 1 352 ? 71.251 96.078 95.428 1.00 33.32 ? 388 GLN B CG 1 ATOM 8775 C CD . GLN B 1 352 ? 72.033 96.876 96.457 1.00 36.06 ? 388 GLN B CD 1 ATOM 8776 O OE1 . GLN B 1 352 ? 72.533 97.964 96.164 1.00 35.53 ? 388 GLN B OE1 1 ATOM 8777 N NE2 . GLN B 1 352 ? 72.156 96.327 97.671 1.00 33.05 ? 388 GLN B NE2 1 ATOM 8778 N N . ILE B 1 353 ? 67.499 96.914 92.783 1.00 31.91 ? 389 ILE B N 1 ATOM 8779 C CA . ILE B 1 353 ? 66.525 97.707 92.033 1.00 38.55 ? 389 ILE B CA 1 ATOM 8780 C C . ILE B 1 353 ? 66.751 99.193 92.311 1.00 46.04 ? 389 ILE B C 1 ATOM 8781 O O . ILE B 1 353 ? 67.009 99.582 93.455 1.00 42.66 ? 389 ILE B O 1 ATOM 8782 C CB . ILE B 1 353 ? 65.079 97.352 92.417 1.00 41.36 ? 389 ILE B CB 1 ATOM 8783 C CG1 . ILE B 1 353 ? 64.786 95.870 92.156 1.00 41.78 ? 389 ILE B CG1 1 ATOM 8784 C CG2 . ILE B 1 353 ? 64.094 98.233 91.663 1.00 40.35 ? 389 ILE B CG2 1 ATOM 8785 C CD1 . ILE B 1 353 ? 64.933 95.460 90.741 1.00 40.94 ? 389 ILE B CD1 1 ATOM 8786 N N . ASP B 1 354 ? 66.654 100.017 91.270 1.00 45.13 ? 390 ASP B N 1 ATOM 8787 C CA . ASP B 1 354 ? 66.884 101.462 91.392 1.00 50.16 ? 390 ASP B CA 1 ATOM 8788 C C . ASP B 1 354 ? 68.366 101.807 91.525 1.00 51.61 ? 390 ASP B C 1 ATOM 8789 O O . ASP B 1 354 ? 68.716 102.946 91.839 1.00 57.13 ? 390 ASP B O 1 ATOM 8790 C CB . ASP B 1 354 ? 66.097 102.068 92.567 1.00 48.32 ? 390 ASP B CB 1 ATOM 8791 C CG . ASP B 1 354 ? 64.598 102.068 92.330 1.00 53.22 ? 390 ASP B CG 1 ATOM 8792 O OD1 . ASP B 1 354 ? 64.188 102.197 91.154 1.00 56.26 ? 390 ASP B OD1 1 ATOM 8793 O OD2 . ASP B 1 354 ? 63.832 101.934 93.316 1.00 55.83 ? 390 ASP B OD2 1 ATOM 8794 N N . LYS B 1 355 ? 69.232 100.819 91.317 1.00 45.83 ? 391 LYS B N 1 ATOM 8795 C CA . LYS B 1 355 ? 70.666 101.070 91.192 1.00 44.62 ? 391 LYS B CA 1 ATOM 8796 C C . LYS B 1 355 ? 71.163 100.464 89.880 1.00 50.38 ? 391 LYS B C 1 ATOM 8797 O O . LYS B 1 355 ? 70.626 99.461 89.402 1.00 48.05 ? 391 LYS B O 1 ATOM 8798 C CB . LYS B 1 355 ? 71.442 100.532 92.395 1.00 43.17 ? 391 LYS B CB 1 ATOM 8799 C CG . LYS B 1 355 ? 71.042 101.174 93.730 1.00 45.75 ? 391 LYS B CG 1 ATOM 8800 C CD . LYS B 1 355 ? 72.244 101.766 94.473 1.00 47.29 ? 391 LYS B CD 1 ATOM 8801 N N . LYS B 1 356 ? 72.178 101.086 89.292 1.00 50.76 ? 392 LYS B N 1 ATOM 8802 C CA . LYS B 1 356 ? 72.645 100.702 87.967 1.00 50.94 ? 392 LYS B CA 1 ATOM 8803 C C . LYS B 1 356 ? 73.757 99.659 88.044 1.00 51.71 ? 392 LYS B C 1 ATOM 8804 O O . LYS B 1 356 ? 74.529 99.624 89.010 1.00 51.49 ? 392 LYS B O 1 ATOM 8805 C CB . LYS B 1 356 ? 73.135 101.942 87.204 1.00 55.00 ? 392 LYS B CB 1 ATOM 8806 C CG . LYS B 1 356 ? 72.146 103.113 87.191 1.00 51.85 ? 392 LYS B CG 1 ATOM 8807 N N . ASP B 1 357 ? 73.842 98.812 87.022 1.00 50.40 ? 393 ASP B N 1 ATOM 8808 C CA . ASP B 1 357 ? 74.893 97.802 86.969 1.00 53.27 ? 393 ASP B CA 1 ATOM 8809 C C . ASP B 1 357 ? 74.658 96.700 88.012 1.00 50.38 ? 393 ASP B C 1 ATOM 8810 O O . ASP B 1 357 ? 73.554 96.550 88.526 1.00 46.68 ? 393 ASP B O 1 ATOM 8811 C CB . ASP B 1 357 ? 76.271 98.447 87.170 1.00 53.19 ? 393 ASP B CB 1 ATOM 8812 C CG . ASP B 1 357 ? 77.170 98.310 85.947 1.00 68.11 ? 393 ASP B CG 1 ATOM 8813 O OD1 . ASP B 1 357 ? 76.963 99.062 84.959 1.00 61.31 ? 393 ASP B OD1 1 ATOM 8814 O OD2 . ASP B 1 357 ? 78.090 97.451 85.981 1.00 70.54 ? 393 ASP B OD2 1 ATOM 8815 N N . CYS B 1 358 ? 75.697 95.923 88.302 1.00 43.45 ? 394 CYS B N 1 ATOM 8816 C CA . CYS B 1 358 ? 75.577 94.820 89.244 1.00 41.84 ? 394 CYS B CA 1 ATOM 8817 C C . CYS B 1 358 ? 76.934 94.447 89.793 1.00 40.69 ? 394 CYS B C 1 ATOM 8818 O O . CYS B 1 358 ? 77.967 94.938 89.335 1.00 43.15 ? 394 CYS B O 1 ATOM 8819 C CB . CYS B 1 358 ? 74.921 93.595 88.594 1.00 39.70 ? 394 CYS B CB 1 ATOM 8820 S SG . CYS B 1 358 ? 75.929 92.792 87.310 1.00 47.23 ? 394 CYS B SG 1 ATOM 8821 N N . THR B 1 359 ? 76.918 93.561 90.780 1.00 37.41 ? 395 THR B N 1 ATOM 8822 C CA . THR B 1 359 ? 78.120 93.172 91.481 1.00 33.45 ? 395 THR B CA 1 ATOM 8823 C C . THR B 1 359 ? 78.289 91.666 91.367 1.00 33.92 ? 395 THR B C 1 ATOM 8824 O O . THR B 1 359 ? 77.414 90.900 91.781 1.00 31.45 ? 395 THR B O 1 ATOM 8825 C CB . THR B 1 359 ? 78.015 93.582 92.961 1.00 35.17 ? 395 THR B CB 1 ATOM 8826 O OG1 . THR B 1 359 ? 77.799 95.001 93.042 1.00 35.64 ? 395 THR B OG1 1 ATOM 8827 C CG2 . THR B 1 359 ? 79.272 93.195 93.731 1.00 35.21 ? 395 THR B CG2 1 ATOM 8828 N N . PHE B 1 360 ? 79.401 91.232 90.785 1.00 31.48 ? 396 PHE B N 1 ATOM 8829 C CA . PHE B 1 360 ? 79.650 89.802 90.706 1.00 36.78 ? 396 PHE B CA 1 ATOM 8830 C C . PHE B 1 360 ? 80.032 89.290 92.077 1.00 32.86 ? 396 PHE B C 1 ATOM 8831 O O . PHE B 1 360 ? 80.850 89.898 92.769 1.00 34.89 ? 396 PHE B O 1 ATOM 8832 C CB . PHE B 1 360 ? 80.741 89.478 89.689 1.00 33.95 ? 396 PHE B CB 1 ATOM 8833 C CG . PHE B 1 360 ? 80.295 89.621 88.273 1.00 35.59 ? 396 PHE B CG 1 ATOM 8834 C CD1 . PHE B 1 360 ? 79.663 88.574 87.624 1.00 35.22 ? 396 PHE B CD1 1 ATOM 8835 C CD2 . PHE B 1 360 ? 80.495 90.810 87.587 1.00 36.00 ? 396 PHE B CD2 1 ATOM 8836 C CE1 . PHE B 1 360 ? 79.245 88.706 86.322 1.00 33.09 ? 396 PHE B CE1 1 ATOM 8837 C CE2 . PHE B 1 360 ? 80.075 90.945 86.288 1.00 38.56 ? 396 PHE B CE2 1 ATOM 8838 C CZ . PHE B 1 360 ? 79.452 89.888 85.651 1.00 39.61 ? 396 PHE B CZ 1 ATOM 8839 N N . ILE B 1 361 ? 79.423 88.181 92.476 1.00 32.38 ? 397 ILE B N 1 ATOM 8840 C CA . ILE B 1 361 ? 79.764 87.553 93.738 1.00 28.17 ? 397 ILE B CA 1 ATOM 8841 C C . ILE B 1 361 ? 80.576 86.273 93.553 1.00 33.69 ? 397 ILE B C 1 ATOM 8842 O O . ILE B 1 361 ? 81.160 85.767 94.512 1.00 30.16 ? 397 ILE B O 1 ATOM 8843 C CB . ILE B 1 361 ? 78.524 87.313 94.611 1.00 31.05 ? 397 ILE B CB 1 ATOM 8844 C CG1 . ILE B 1 361 ? 77.712 86.118 94.121 1.00 28.04 ? 397 ILE B CG1 1 ATOM 8845 C CG2 . ILE B 1 361 ? 77.661 88.563 94.650 1.00 32.56 ? 397 ILE B CG2 1 ATOM 8846 C CD1 . ILE B 1 361 ? 76.505 85.820 94.980 1.00 29.05 ? 397 ILE B CD1 1 ATOM 8847 N N . THR B 1 362 ? 80.619 85.744 92.329 1.00 30.39 ? 398 THR B N 1 ATOM 8848 C CA . THR B 1 362 ? 81.542 84.649 92.015 1.00 31.16 ? 398 THR B CA 1 ATOM 8849 C C . THR B 1 362 ? 82.405 84.993 90.795 1.00 32.32 ? 398 THR B C 1 ATOM 8850 O O . THR B 1 362 ? 82.012 85.808 89.955 1.00 28.81 ? 398 THR B O 1 ATOM 8851 C CB . THR B 1 362 ? 80.811 83.298 91.780 1.00 28.35 ? 398 THR B CB 1 ATOM 8852 O OG1 . THR B 1 362 ? 79.959 83.400 90.631 1.00 31.70 ? 398 THR B OG1 1 ATOM 8853 C CG2 . THR B 1 362 ? 79.973 82.918 92.995 1.00 27.68 ? 398 THR B CG2 1 ATOM 8854 N N . LYS B 1 363 ? 83.587 84.388 90.711 1.00 32.16 ? 399 LYS B N 1 ATOM 8855 C CA . LYS B 1 363 ? 84.457 84.589 89.551 1.00 34.96 ? 399 LYS B CA 1 ATOM 8856 C C . LYS B 1 363 ? 85.395 83.398 89.349 1.00 36.97 ? 399 LYS B C 1 ATOM 8857 O O . LYS B 1 363 ? 85.483 82.518 90.212 1.00 34.05 ? 399 LYS B O 1 ATOM 8858 C CB . LYS B 1 363 ? 85.272 85.870 89.719 1.00 40.92 ? 399 LYS B CB 1 ATOM 8859 C CG . LYS B 1 363 ? 86.207 85.829 90.915 1.00 43.47 ? 399 LYS B CG 1 ATOM 8860 C CD . LYS B 1 363 ? 87.066 87.090 91.034 1.00 52.67 ? 399 LYS B CD 1 ATOM 8861 C CE . LYS B 1 363 ? 87.807 87.113 92.377 1.00 56.67 ? 399 LYS B CE 1 ATOM 8862 N NZ . LYS B 1 363 ? 86.882 86.864 93.526 1.00 54.32 ? 399 LYS B NZ 1 ATOM 8863 N N . GLY B 1 364 ? 86.083 83.365 88.206 1.00 33.20 ? 400 GLY B N 1 ATOM 8864 C CA . GLY B 1 364 ? 87.036 82.304 87.925 1.00 35.19 ? 400 GLY B CA 1 ATOM 8865 C C . GLY B 1 364 ? 86.824 81.610 86.582 1.00 32.14 ? 400 GLY B C 1 ATOM 8866 O O . GLY B 1 364 ? 85.815 81.835 85.909 1.00 30.15 ? 400 GLY B O 1 ATOM 8867 N N . THR B 1 365 ? 87.776 80.763 86.199 1.00 32.65 ? 401 THR B N 1 ATOM 8868 C CA . THR B 1 365 ? 87.715 80.063 84.913 1.00 34.86 ? 401 THR B CA 1 ATOM 8869 C C . THR B 1 365 ? 86.872 78.784 85.044 1.00 31.48 ? 401 THR B C 1 ATOM 8870 O O . THR B 1 365 ? 87.370 77.657 84.945 1.00 34.95 ? 401 THR B O 1 ATOM 8871 C CB . THR B 1 365 ? 89.131 79.776 84.365 1.00 33.54 ? 401 THR B CB 1 ATOM 8872 O OG1 . THR B 1 365 ? 89.765 78.791 85.184 1.00 42.56 ? 401 THR B OG1 1 ATOM 8873 C CG2 . THR B 1 365 ? 89.974 81.044 84.408 1.00 36.46 ? 401 THR B CG2 1 ATOM 8874 N N . TRP B 1 366 ? 85.586 78.996 85.296 1.00 30.75 ? 402 TRP B N 1 ATOM 8875 C CA . TRP B 1 366 ? 84.586 77.944 85.410 1.00 31.31 ? 402 TRP B CA 1 ATOM 8876 C C . TRP B 1 366 ? 83.258 78.680 85.362 1.00 31.11 ? 402 TRP B C 1 ATOM 8877 O O . TRP B 1 366 ? 83.248 79.917 85.313 1.00 32.20 ? 402 TRP B O 1 ATOM 8878 C CB . TRP B 1 366 ? 84.739 77.144 86.718 1.00 30.53 ? 402 TRP B CB 1 ATOM 8879 C CG . TRP B 1 366 ? 84.890 77.985 87.964 1.00 29.18 ? 402 TRP B CG 1 ATOM 8880 C CD1 . TRP B 1 366 ? 86.064 78.461 88.500 1.00 30.02 ? 402 TRP B CD1 1 ATOM 8881 C CD2 . TRP B 1 366 ? 83.841 78.444 88.834 1.00 26.68 ? 402 TRP B CD2 1 ATOM 8882 N NE1 . TRP B 1 366 ? 85.804 79.191 89.631 1.00 28.39 ? 402 TRP B NE1 1 ATOM 8883 C CE2 . TRP B 1 366 ? 84.453 79.195 89.866 1.00 31.20 ? 402 TRP B CE2 1 ATOM 8884 C CE3 . TRP B 1 366 ? 82.448 78.295 88.842 1.00 26.04 ? 402 TRP B CE3 1 ATOM 8885 C CZ2 . TRP B 1 366 ? 83.715 79.793 90.902 1.00 27.73 ? 402 TRP B CZ2 1 ATOM 8886 C CZ3 . TRP B 1 366 ? 81.713 78.892 89.867 1.00 30.89 ? 402 TRP B CZ3 1 ATOM 8887 C CH2 . TRP B 1 366 ? 82.352 79.632 90.885 1.00 27.46 ? 402 TRP B CH2 1 ATOM 8888 N N . GLU B 1 367 ? 82.140 77.958 85.360 1.00 28.70 ? 403 GLU B N 1 ATOM 8889 C CA . GLU B 1 367 ? 80.848 78.633 85.267 1.00 29.06 ? 403 GLU B CA 1 ATOM 8890 C C . GLU B 1 367 ? 79.835 78.169 86.305 1.00 25.77 ? 403 GLU B C 1 ATOM 8891 O O . GLU B 1 367 ? 79.852 77.016 86.733 1.00 28.81 ? 403 GLU B O 1 ATOM 8892 C CB . GLU B 1 367 ? 80.243 78.487 83.865 1.00 27.35 ? 403 GLU B CB 1 ATOM 8893 C CG . GLU B 1 367 ? 81.120 79.007 82.731 1.00 32.05 ? 403 GLU B CG 1 ATOM 8894 C CD . GLU B 1 367 ? 80.327 79.378 81.472 1.00 32.02 ? 403 GLU B CD 1 ATOM 8895 O OE1 . GLU B 1 367 ? 79.353 78.671 81.121 1.00 33.43 ? 403 GLU B OE1 1 ATOM 8896 O OE2 . GLU B 1 367 ? 80.676 80.398 80.832 1.00 37.25 ? 403 GLU B OE2 1 ATOM 8897 N N . VAL B 1 368 ? 78.963 79.088 86.712 1.00 26.49 ? 404 VAL B N 1 ATOM 8898 C CA . VAL B 1 368 ? 77.787 78.754 87.500 1.00 27.34 ? 404 VAL B CA 1 ATOM 8899 C C . VAL B 1 368 ? 76.739 78.209 86.544 1.00 29.08 ? 404 VAL B C 1 ATOM 8900 O O . VAL B 1 368 ? 76.449 78.829 85.523 1.00 25.83 ? 404 VAL B O 1 ATOM 8901 C CB . VAL B 1 368 ? 77.220 80.001 88.193 1.00 26.67 ? 404 VAL B CB 1 ATOM 8902 C CG1 . VAL B 1 368 ? 75.928 79.679 88.919 1.00 24.25 ? 404 VAL B CG1 1 ATOM 8903 C CG2 . VAL B 1 368 ? 78.264 80.580 89.143 1.00 26.40 ? 404 VAL B CG2 1 ATOM 8904 N N . ILE B 1 369 ? 76.186 77.045 86.871 1.00 27.80 ? 405 ILE B N 1 ATOM 8905 C CA . ILE B 1 369 ? 75.222 76.379 86.001 1.00 26.21 ? 405 ILE B CA 1 ATOM 8906 C C . ILE B 1 369 ? 73.799 76.834 86.332 1.00 29.16 ? 405 ILE B C 1 ATOM 8907 O O . ILE B 1 369 ? 73.014 77.128 85.438 1.00 26.89 ? 405 ILE B O 1 ATOM 8908 C CB . ILE B 1 369 ? 75.360 74.833 86.079 1.00 29.76 ? 405 ILE B CB 1 ATOM 8909 C CG1 . ILE B 1 369 ? 76.253 74.320 84.952 1.00 39.50 ? 405 ILE B CG1 1 ATOM 8910 C CG2 . ILE B 1 369 ? 74.017 74.154 85.880 1.00 36.34 ? 405 ILE B CG2 1 ATOM 8911 C CD1 . ILE B 1 369 ? 77.714 74.429 85.200 1.00 33.21 ? 405 ILE B CD1 1 ATOM 8912 N N . GLY B 1 370 ? 73.469 76.912 87.618 1.00 25.87 ? 406 GLY B N 1 ATOM 8913 C CA . GLY B 1 370 ? 72.161 77.387 88.041 1.00 24.30 ? 406 GLY B CA 1 ATOM 8914 C C . GLY B 1 370 ? 72.166 77.933 89.469 1.00 27.30 ? 406 GLY B C 1 ATOM 8915 O O . GLY B 1 370 ? 72.921 77.452 90.321 1.00 24.26 ? 406 GLY B O 1 ATOM 8916 N N . ILE B 1 371 ? 71.329 78.936 89.737 1.00 24.99 ? 407 ILE B N 1 ATOM 8917 C CA . ILE B 1 371 ? 71.084 79.364 91.116 1.00 29.33 ? 407 ILE B CA 1 ATOM 8918 C C . ILE B 1 371 ? 69.898 78.569 91.674 1.00 31.20 ? 407 ILE B C 1 ATOM 8919 O O . ILE B 1 371 ? 68.790 78.643 91.131 1.00 34.83 ? 407 ILE B O 1 ATOM 8920 C CB . ILE B 1 371 ? 70.759 80.861 91.199 1.00 27.84 ? 407 ILE B CB 1 ATOM 8921 C CG1 . ILE B 1 371 ? 71.940 81.701 90.709 1.00 26.78 ? 407 ILE B CG1 1 ATOM 8922 C CG2 . ILE B 1 371 ? 70.379 81.251 92.636 1.00 25.23 ? 407 ILE B CG2 1 ATOM 8923 C CD1 . ILE B 1 371 ? 71.583 83.186 90.552 1.00 26.74 ? 407 ILE B CD1 1 ATOM 8924 N N . GLU B 1 372 ? 70.119 77.817 92.749 1.00 27.23 ? 408 GLU B N 1 ATOM 8925 C CA . GLU B 1 372 ? 69.131 76.834 93.213 1.00 26.86 ? 408 GLU B CA 1 ATOM 8926 C C . GLU B 1 372 ? 68.295 77.248 94.420 1.00 31.46 ? 408 GLU B C 1 ATOM 8927 O O . GLU B 1 372 ? 67.136 76.848 94.538 1.00 31.22 ? 408 GLU B O 1 ATOM 8928 C CB . GLU B 1 372 ? 69.813 75.486 93.507 1.00 30.71 ? 408 GLU B CB 1 ATOM 8929 C CG . GLU B 1 372 ? 70.614 74.942 92.336 1.00 32.08 ? 408 GLU B CG 1 ATOM 8930 C CD . GLU B 1 372 ? 69.762 74.782 91.092 1.00 34.26 ? 408 GLU B CD 1 ATOM 8931 O OE1 . GLU B 1 372 ? 68.584 74.365 91.221 1.00 33.05 ? 408 GLU B OE1 1 ATOM 8932 O OE2 . GLU B 1 372 ? 70.256 75.096 89.985 1.00 42.23 ? 408 GLU B OE2 1 ATOM 8933 N N . ALA B 1 373 ? 68.877 78.012 95.338 1.00 26.30 ? 409 ALA B N 1 ATOM 8934 C CA . ALA B 1 373 ? 68.110 78.515 96.479 1.00 28.73 ? 409 ALA B CA 1 ATOM 8935 C C . ALA B 1 373 ? 68.745 79.776 97.041 1.00 27.47 ? 409 ALA B C 1 ATOM 8936 O O . ALA B 1 373 ? 69.947 80.009 96.891 1.00 26.64 ? 409 ALA B O 1 ATOM 8937 C CB . ALA B 1 373 ? 67.972 77.440 97.594 1.00 26.98 ? 409 ALA B CB 1 ATOM 8938 N N . LEU B 1 374 ? 67.932 80.575 97.713 1.00 31.74 ? 410 LEU B N 1 ATOM 8939 C CA . LEU B 1 374 ? 68.389 81.833 98.274 1.00 28.55 ? 410 LEU B CA 1 ATOM 8940 C C . LEU B 1 374 ? 67.721 82.018 99.625 1.00 31.61 ? 410 LEU B C 1 ATOM 8941 O O . LEU B 1 374 ? 66.495 81.944 99.718 1.00 29.61 ? 410 LEU B O 1 ATOM 8942 C CB . LEU B 1 374 ? 68.001 82.985 97.324 1.00 31.83 ? 410 LEU B CB 1 ATOM 8943 C CG . LEU B 1 374 ? 68.223 84.435 97.765 1.00 31.61 ? 410 LEU B CG 1 ATOM 8944 C CD1 . LEU B 1 374 ? 69.710 84.729 97.958 1.00 31.83 ? 410 LEU B CD1 1 ATOM 8945 C CD2 . LEU B 1 374 ? 67.624 85.386 96.754 1.00 32.42 ? 410 LEU B CD2 1 ATOM 8946 N N . THR B 1 375 ? 68.521 82.223 100.673 1.00 32.64 ? 411 THR B N 1 ATOM 8947 C CA . THR B 1 375 ? 68.001 82.636 101.976 1.00 31.47 ? 411 THR B CA 1 ATOM 8948 C C . THR B 1 375 ? 68.652 83.967 102.364 1.00 35.97 ? 411 THR B C 1 ATOM 8949 O O . THR B 1 375 ? 69.510 84.480 101.645 1.00 32.98 ? 411 THR B O 1 ATOM 8950 C CB . THR B 1 375 ? 68.281 81.581 103.087 1.00 32.62 ? 411 THR B CB 1 ATOM 8951 O OG1 . THR B 1 375 ? 69.683 81.518 103.347 1.00 32.74 ? 411 THR B OG1 1 ATOM 8952 C CG2 . THR B 1 375 ? 67.805 80.214 102.660 1.00 35.90 ? 411 THR B CG2 1 ATOM 8953 N N . SER B 1 376 ? 68.268 84.520 103.509 1.00 39.25 ? 412 SER B N 1 ATOM 8954 C CA . SER B 1 376 ? 68.879 85.767 103.974 1.00 39.73 ? 412 SER B CA 1 ATOM 8955 C C . SER B 1 376 ? 70.387 85.609 104.212 1.00 37.43 ? 412 SER B C 1 ATOM 8956 O O . SER B 1 376 ? 71.148 86.558 104.036 1.00 40.89 ? 412 SER B O 1 ATOM 8957 C CB . SER B 1 376 ? 68.185 86.267 105.246 1.00 42.82 ? 412 SER B CB 1 ATOM 8958 O OG . SER B 1 376 ? 68.256 85.296 106.279 1.00 42.47 ? 412 SER B OG 1 ATOM 8959 N N . ASP B 1 377 ? 70.812 84.405 104.594 1.00 32.64 ? 413 ASP B N 1 ATOM 8960 C CA . ASP B 1 377 ? 72.219 84.129 104.890 1.00 30.02 ? 413 ASP B CA 1 ATOM 8961 C C . ASP B 1 377 ? 73.075 83.561 103.748 1.00 30.96 ? 413 ASP B C 1 ATOM 8962 O O . ASP B 1 377 ? 74.258 83.867 103.662 1.00 31.64 ? 413 ASP B O 1 ATOM 8963 C CB . ASP B 1 377 ? 72.327 83.201 106.100 1.00 35.31 ? 413 ASP B CB 1 ATOM 8964 C CG . ASP B 1 377 ? 72.074 83.927 107.408 1.00 49.47 ? 413 ASP B CG 1 ATOM 8965 O OD1 . ASP B 1 377 ? 71.771 85.144 107.347 1.00 47.42 ? 413 ASP B OD1 1 ATOM 8966 O OD2 . ASP B 1 377 ? 72.174 83.290 108.488 1.00 53.69 ? 413 ASP B OD2 1 ATOM 8967 N N . TYR B 1 378 ? 72.502 82.725 102.890 1.00 30.80 ? 414 TYR B N 1 ATOM 8968 C CA . TYR B 1 378 ? 73.304 82.049 101.863 1.00 27.74 ? 414 TYR B CA 1 ATOM 8969 C C . TYR B 1 378 ? 72.609 82.013 100.502 1.00 28.06 ? 414 TYR B C 1 ATOM 8970 O O . TYR B 1 378 ? 71.380 82.035 100.425 1.00 28.34 ? 414 TYR B O 1 ATOM 8971 C CB . TYR B 1 378 ? 73.603 80.605 102.285 1.00 30.61 ? 414 TYR B CB 1 ATOM 8972 C CG . TYR B 1 378 ? 74.579 80.471 103.424 1.00 34.06 ? 414 TYR B CG 1 ATOM 8973 C CD1 . TYR B 1 378 ? 75.949 80.563 103.199 1.00 34.25 ? 414 TYR B CD1 1 ATOM 8974 C CD2 . TYR B 1 378 ? 74.137 80.239 104.732 1.00 36.51 ? 414 TYR B CD2 1 ATOM 8975 C CE1 . TYR B 1 378 ? 76.864 80.439 104.244 1.00 35.76 ? 414 TYR B CE1 1 ATOM 8976 C CE2 . TYR B 1 378 ? 75.044 80.109 105.783 1.00 37.65 ? 414 TYR B CE2 1 ATOM 8977 C CZ . TYR B 1 378 ? 76.408 80.216 105.528 1.00 37.34 ? 414 TYR B CZ 1 ATOM 8978 O OH . TYR B 1 378 ? 77.323 80.088 106.559 1.00 45.01 ? 414 TYR B OH 1 ATOM 8979 N N . LEU B 1 379 ? 73.402 81.949 99.430 1.00 28.29 ? 415 LEU B N 1 ATOM 8980 C CA . LEU B 1 379 ? 72.863 81.623 98.116 1.00 26.42 ? 415 LEU B CA 1 ATOM 8981 C C . LEU B 1 379 ? 73.461 80.283 97.694 1.00 25.61 ? 415 LEU B C 1 ATOM 8982 O O . LEU B 1 379 ? 74.671 80.094 97.773 1.00 28.56 ? 415 LEU B O 1 ATOM 8983 C CB . LEU B 1 379 ? 73.175 82.723 97.096 1.00 23.89 ? 415 LEU B CB 1 ATOM 8984 C CG . LEU B 1 379 ? 72.702 82.494 95.654 1.00 31.02 ? 415 LEU B CG 1 ATOM 8985 C CD1 . LEU B 1 379 ? 72.592 83.813 94.868 1.00 23.86 ? 415 LEU B CD1 1 ATOM 8986 C CD2 . LEU B 1 379 ? 73.628 81.521 94.930 1.00 26.16 ? 415 LEU B CD2 1 ATOM 8987 N N . TYR B 1 380 ? 72.609 79.352 97.275 1.00 27.53 ? 416 TYR B N 1 ATOM 8988 C CA . TYR B 1 380 ? 73.061 78.016 96.890 1.00 28.44 ? 416 TYR B CA 1 ATOM 8989 C C . TYR B 1 380 ? 73.073 77.917 95.375 1.00 28.38 ? 416 TYR B C 1 ATOM 8990 O O . TYR B 1 380 ? 72.155 78.384 94.708 1.00 29.05 ? 416 TYR B O 1 ATOM 8991 C CB . TYR B 1 380 ? 72.158 76.928 97.474 1.00 27.38 ? 416 TYR B CB 1 ATOM 8992 C CG . TYR B 1 380 ? 72.137 76.879 98.990 1.00 30.62 ? 416 TYR B CG 1 ATOM 8993 C CD1 . TYR B 1 380 ? 71.263 77.680 99.717 1.00 30.12 ? 416 TYR B CD1 1 ATOM 8994 C CD2 . TYR B 1 380 ? 72.983 76.032 99.694 1.00 30.64 ? 416 TYR B CD2 1 ATOM 8995 C CE1 . TYR B 1 380 ? 71.234 77.642 101.116 1.00 33.10 ? 416 TYR B CE1 1 ATOM 8996 C CE2 . TYR B 1 380 ? 72.956 75.982 101.101 1.00 35.03 ? 416 TYR B CE2 1 ATOM 8997 C CZ . TYR B 1 380 ? 72.079 76.792 101.793 1.00 34.17 ? 416 TYR B CZ 1 ATOM 8998 O OH . TYR B 1 380 ? 72.044 76.772 103.165 1.00 36.16 ? 416 TYR B OH 1 ATOM 8999 N N . TYR B 1 381 ? 74.128 77.332 94.829 1.00 28.04 ? 417 TYR B N 1 ATOM 9000 C CA . TYR B 1 381 ? 74.243 77.230 93.382 1.00 27.50 ? 417 TYR B CA 1 ATOM 9001 C C . TYR B 1 381 ? 74.996 75.969 92.961 1.00 28.26 ? 417 TYR B C 1 ATOM 9002 O O . TYR B 1 381 ? 75.769 75.402 93.744 1.00 24.59 ? 417 TYR B O 1 ATOM 9003 C CB . TYR B 1 381 ? 74.911 78.489 92.809 1.00 25.84 ? 417 TYR B CB 1 ATOM 9004 C CG . TYR B 1 381 ? 76.373 78.645 93.157 1.00 27.65 ? 417 TYR B CG 1 ATOM 9005 C CD1 . TYR B 1 381 ? 77.354 78.140 92.324 1.00 27.31 ? 417 TYR B CD1 1 ATOM 9006 C CD2 . TYR B 1 381 ? 76.776 79.331 94.298 1.00 29.56 ? 417 TYR B CD2 1 ATOM 9007 C CE1 . TYR B 1 381 ? 78.692 78.281 92.629 1.00 29.34 ? 417 TYR B CE1 1 ATOM 9008 C CE2 . TYR B 1 381 ? 78.129 79.490 94.606 1.00 27.46 ? 417 TYR B CE2 1 ATOM 9009 C CZ . TYR B 1 381 ? 79.074 78.958 93.775 1.00 29.49 ? 417 TYR B CZ 1 ATOM 9010 O OH . TYR B 1 381 ? 80.411 79.090 94.058 1.00 28.65 ? 417 TYR B OH 1 ATOM 9011 N N . ILE B 1 382 ? 74.734 75.525 91.733 1.00 26.04 ? 418 ILE B N 1 ATOM 9012 C CA . ILE B 1 382 ? 75.457 74.420 91.123 1.00 22.92 ? 418 ILE B CA 1 ATOM 9013 C C . ILE B 1 382 ? 76.498 74.994 90.175 1.00 26.18 ? 418 ILE B C 1 ATOM 9014 O O . ILE B 1 382 ? 76.199 75.910 89.406 1.00 24.75 ? 418 ILE B O 1 ATOM 9015 C CB . ILE B 1 382 ? 74.529 73.539 90.271 1.00 24.34 ? 418 ILE B CB 1 ATOM 9016 C CG1 . ILE B 1 382 ? 73.403 72.942 91.114 1.00 26.52 ? 418 ILE B CG1 1 ATOM 9017 C CG2 . ILE B 1 382 ? 75.350 72.425 89.563 1.00 25.01 ? 418 ILE B CG2 1 ATOM 9018 C CD1 . ILE B 1 382 ? 73.870 71.886 92.069 1.00 27.87 ? 418 ILE B CD1 1 ATOM 9019 N N . SER B 1 383 ? 77.715 74.462 90.224 1.00 22.87 ? 419 SER B N 1 ATOM 9020 C CA . SER B 1 383 ? 78.763 74.919 89.317 1.00 26.77 ? 419 SER B CA 1 ATOM 9021 C C . SER B 1 383 ? 79.666 73.772 88.903 1.00 25.61 ? 419 SER B C 1 ATOM 9022 O O . SER B 1 383 ? 79.590 72.682 89.469 1.00 25.18 ? 419 SER B O 1 ATOM 9023 C CB . SER B 1 383 ? 79.623 76.000 89.970 1.00 25.34 ? 419 SER B CB 1 ATOM 9024 O OG . SER B 1 383 ? 80.780 75.415 90.541 1.00 28.05 ? 419 SER B OG 1 ATOM 9025 N N . ASN B 1 384 ? 80.543 74.030 87.939 1.00 26.68 ? 420 ASN B N 1 ATOM 9026 C CA . ASN B 1 384 ? 81.497 73.016 87.503 1.00 30.21 ? 420 ASN B CA 1 ATOM 9027 C C . ASN B 1 384 ? 82.941 73.324 87.938 1.00 30.18 ? 420 ASN B C 1 ATOM 9028 O O . ASN B 1 384 ? 83.900 72.865 87.324 1.00 29.69 ? 420 ASN B O 1 ATOM 9029 C CB . ASN B 1 384 ? 81.377 72.714 85.987 1.00 27.82 ? 420 ASN B CB 1 ATOM 9030 C CG . ASN B 1 384 ? 81.652 73.923 85.109 1.00 30.00 ? 420 ASN B CG 1 ATOM 9031 O OD1 . ASN B 1 384 ? 82.034 74.985 85.597 1.00 26.70 ? 420 ASN B OD1 1 ATOM 9032 N ND2 . ASN B 1 384 ? 81.481 73.753 83.790 1.00 28.67 ? 420 ASN B ND2 1 ATOM 9033 N N . GLU B 1 385 ? 83.085 74.080 89.026 1.00 31.23 ? 421 GLU B N 1 ATOM 9034 C CA . GLU B 1 385 ? 84.416 74.463 89.501 1.00 30.05 ? 421 GLU B CA 1 ATOM 9035 C C . GLU B 1 385 ? 85.285 73.279 89.922 1.00 26.26 ? 421 GLU B C 1 ATOM 9036 O O . GLU B 1 385 ? 86.474 73.269 89.664 1.00 33.75 ? 421 GLU B O 1 ATOM 9037 C CB . GLU B 1 385 ? 84.332 75.471 90.665 1.00 30.82 ? 421 GLU B CB 1 ATOM 9038 C CG . GLU B 1 385 ? 85.710 75.801 91.267 1.00 32.69 ? 421 GLU B CG 1 ATOM 9039 C CD . GLU B 1 385 ? 85.661 76.877 92.355 1.00 36.91 ? 421 GLU B CD 1 ATOM 9040 O OE1 . GLU B 1 385 ? 84.563 77.147 92.894 1.00 34.87 ? 421 GLU B OE1 1 ATOM 9041 O OE2 . GLU B 1 385 ? 86.735 77.445 92.662 1.00 35.09 ? 421 GLU B OE2 1 ATOM 9042 N N . TYR B 1 386 ? 84.689 72.287 90.572 1.00 31.23 ? 422 TYR B N 1 ATOM 9043 C CA . TYR B 1 386 ? 85.462 71.254 91.259 1.00 33.62 ? 422 TYR B CA 1 ATOM 9044 C C . TYR B 1 386 ? 86.428 70.518 90.345 1.00 35.00 ? 422 TYR B C 1 ATOM 9045 O O . TYR B 1 386 ? 86.025 69.998 89.305 1.00 33.88 ? 422 TYR B O 1 ATOM 9046 C CB . TYR B 1 386 ? 84.535 70.248 91.938 1.00 33.02 ? 422 TYR B CB 1 ATOM 9047 C CG . TYR B 1 386 ? 85.268 69.299 92.844 1.00 37.94 ? 422 TYR B CG 1 ATOM 9048 C CD1 . TYR B 1 386 ? 86.066 69.784 93.872 1.00 44.49 ? 422 TYR B CD1 1 ATOM 9049 C CD2 . TYR B 1 386 ? 85.153 67.926 92.691 1.00 40.69 ? 422 TYR B CD2 1 ATOM 9050 C CE1 . TYR B 1 386 ? 86.744 68.926 94.719 1.00 48.99 ? 422 TYR B CE1 1 ATOM 9051 C CE2 . TYR B 1 386 ? 85.824 67.059 93.534 1.00 43.62 ? 422 TYR B CE2 1 ATOM 9052 C CZ . TYR B 1 386 ? 86.623 67.569 94.543 1.00 46.15 ? 422 TYR B CZ 1 ATOM 9053 O OH . TYR B 1 386 ? 87.297 66.727 95.396 1.00 52.94 ? 422 TYR B OH 1 ATOM 9054 N N . LYS B 1 387 ? 87.694 70.465 90.760 1.00 32.28 ? 423 LYS B N 1 ATOM 9055 C CA . LYS B 1 387 ? 88.763 69.803 90.013 1.00 40.73 ? 423 LYS B CA 1 ATOM 9056 C C . LYS B 1 387 ? 88.867 70.333 88.593 1.00 39.10 ? 423 LYS B C 1 ATOM 9057 O O . LYS B 1 387 ? 89.458 69.689 87.737 1.00 38.39 ? 423 LYS B O 1 ATOM 9058 C CB . LYS B 1 387 ? 88.567 68.283 89.977 1.00 41.25 ? 423 LYS B CB 1 ATOM 9059 C CG . LYS B 1 387 ? 88.755 67.587 91.311 1.00 45.37 ? 423 LYS B CG 1 ATOM 9060 C CD . LYS B 1 387 ? 90.186 67.698 91.803 1.00 52.71 ? 423 LYS B CD 1 ATOM 9061 C CE . LYS B 1 387 ? 90.447 66.698 92.937 1.00 62.56 ? 423 LYS B CE 1 ATOM 9062 N NZ . LYS B 1 387 ? 90.026 65.306 92.558 1.00 61.45 ? 423 LYS B NZ 1 ATOM 9063 N N . GLY B 1 388 ? 88.284 71.503 88.348 1.00 37.36 ? 424 GLY B N 1 ATOM 9064 C CA . GLY B 1 388 ? 88.339 72.126 87.036 1.00 36.44 ? 424 GLY B CA 1 ATOM 9065 C C . GLY B 1 388 ? 87.800 71.268 85.897 1.00 33.81 ? 424 GLY B C 1 ATOM 9066 O O . GLY B 1 388 ? 88.300 71.352 84.780 1.00 36.87 ? 424 GLY B O 1 ATOM 9067 N N . MET B 1 389 ? 86.788 70.451 86.176 1.00 33.13 ? 425 MET B N 1 ATOM 9068 C CA . MET B 1 389 ? 86.163 69.613 85.152 1.00 34.82 ? 425 MET B CA 1 ATOM 9069 C C . MET B 1 389 ? 84.827 70.210 84.720 1.00 32.39 ? 425 MET B C 1 ATOM 9070 O O . MET B 1 389 ? 83.884 70.261 85.506 1.00 34.59 ? 425 MET B O 1 ATOM 9071 C CB . MET B 1 389 ? 85.930 68.198 85.675 1.00 35.79 ? 425 MET B CB 1 ATOM 9072 C CG . MET B 1 389 ? 87.191 67.471 86.113 1.00 42.41 ? 425 MET B CG 1 ATOM 9073 S SD . MET B 1 389 ? 86.770 65.991 87.065 1.00 56.32 ? 425 MET B SD 1 ATOM 9074 C CE . MET B 1 389 ? 85.908 65.046 85.812 1.00 45.58 ? 425 MET B CE 1 ATOM 9075 N N . PRO B 1 390 ? 84.740 70.659 83.464 1.00 31.73 ? 426 PRO B N 1 ATOM 9076 C CA . PRO B 1 390 ? 83.535 71.319 82.957 1.00 31.57 ? 426 PRO B CA 1 ATOM 9077 C C . PRO B 1 390 ? 82.329 70.384 82.920 1.00 30.56 ? 426 PRO B C 1 ATOM 9078 O O . PRO B 1 390 ? 81.197 70.868 82.870 1.00 31.94 ? 426 PRO B O 1 ATOM 9079 C CB . PRO B 1 390 ? 83.927 71.726 81.525 1.00 32.07 ? 426 PRO B CB 1 ATOM 9080 C CG . PRO B 1 390 ? 85.414 71.682 81.500 1.00 35.61 ? 426 PRO B CG 1 ATOM 9081 C CD . PRO B 1 390 ? 85.803 70.593 82.454 1.00 30.54 ? 426 PRO B CD 1 ATOM 9082 N N . GLY B 1 391 ? 82.575 69.074 82.946 1.00 29.04 ? 427 GLY B N 1 ATOM 9083 C CA . GLY B 1 391 ? 81.524 68.082 82.807 1.00 29.92 ? 427 GLY B CA 1 ATOM 9084 C C . GLY B 1 391 ? 81.100 67.510 84.146 1.00 33.59 ? 427 GLY B C 1 ATOM 9085 O O . GLY B 1 391 ? 80.321 66.554 84.199 1.00 32.34 ? 427 GLY B O 1 ATOM 9086 N N . GLY B 1 392 ? 81.629 68.086 85.227 1.00 29.71 ? 428 GLY B N 1 ATOM 9087 C CA . GLY B 1 392 ? 81.230 67.722 86.573 1.00 27.84 ? 428 GLY B CA 1 ATOM 9088 C C . GLY B 1 392 ? 80.287 68.794 87.085 1.00 32.42 ? 428 GLY B C 1 ATOM 9089 O O . GLY B 1 392 ? 80.282 69.911 86.560 1.00 29.16 ? 428 GLY B O 1 ATOM 9090 N N . ARG B 1 393 ? 79.472 68.455 88.081 1.00 29.88 ? 429 ARG B N 1 ATOM 9091 C CA . ARG B 1 393 ? 78.524 69.410 88.666 1.00 29.58 ? 429 ARG B CA 1 ATOM 9092 C C . ARG B 1 393 ? 78.448 69.205 90.179 1.00 29.14 ? 429 ARG B C 1 ATOM 9093 O O . ARG B 1 393 ? 78.214 68.091 90.646 1.00 28.51 ? 429 ARG B O 1 ATOM 9094 C CB . ARG B 1 393 ? 77.117 69.222 88.076 1.00 28.99 ? 429 ARG B CB 1 ATOM 9095 C CG . ARG B 1 393 ? 76.988 69.389 86.557 1.00 31.84 ? 429 ARG B CG 1 ATOM 9096 C CD . ARG B 1 393 ? 76.447 70.764 86.206 1.00 33.48 ? 429 ARG B CD 1 ATOM 9097 N NE . ARG B 1 393 ? 76.158 70.929 84.782 1.00 34.10 ? 429 ARG B NE 1 ATOM 9098 C CZ . ARG B 1 393 ? 74.972 70.683 84.217 1.00 45.22 ? 429 ARG B CZ 1 ATOM 9099 N NH1 . ARG B 1 393 ? 73.948 70.247 84.954 1.00 38.54 ? 429 ARG B NH1 1 ATOM 9100 N NH2 . ARG B 1 393 ? 74.801 70.877 82.907 1.00 45.09 ? 429 ARG B NH2 1 ATOM 9101 N N . ASN B 1 394 ? 78.621 70.278 90.945 1.00 29.83 ? 430 ASN B N 1 ATOM 9102 C CA . ASN B 1 394 ? 78.532 70.187 92.390 1.00 28.01 ? 430 ASN B CA 1 ATOM 9103 C C . ASN B 1 394 ? 77.744 71.329 93.008 1.00 30.35 ? 430 ASN B C 1 ATOM 9104 O O . ASN B 1 394 ? 77.649 72.409 92.421 1.00 28.45 ? 430 ASN B O 1 ATOM 9105 C CB . ASN B 1 394 ? 79.927 70.141 93.005 1.00 31.31 ? 430 ASN B CB 1 ATOM 9106 C CG . ASN B 1 394 ? 80.502 68.758 93.006 1.00 30.92 ? 430 ASN B CG 1 ATOM 9107 O OD1 . ASN B 1 394 ? 80.072 67.899 93.779 1.00 32.19 ? 430 ASN B OD1 1 ATOM 9108 N ND2 . ASN B 1 394 ? 81.472 68.526 92.140 1.00 30.53 ? 430 ASN B ND2 1 ATOM 9109 N N . LEU B 1 395 ? 77.191 71.080 94.196 1.00 24.48 ? 431 LEU B N 1 ATOM 9110 C CA . LEU B 1 395 ? 76.447 72.107 94.938 1.00 26.00 ? 431 LEU B CA 1 ATOM 9111 C C . LEU B 1 395 ? 77.368 72.922 95.845 1.00 27.98 ? 431 LEU B C 1 ATOM 9112 O O . LEU B 1 395 ? 78.156 72.352 96.604 1.00 28.28 ? 431 LEU B O 1 ATOM 9113 C CB . LEU B 1 395 ? 75.343 71.460 95.777 1.00 23.68 ? 431 LEU B CB 1 ATOM 9114 C CG . LEU B 1 395 ? 74.438 72.390 96.593 1.00 26.78 ? 431 LEU B CG 1 ATOM 9115 C CD1 . LEU B 1 395 ? 73.561 73.225 95.678 1.00 25.73 ? 431 LEU B CD1 1 ATOM 9116 C CD2 . LEU B 1 395 ? 73.579 71.583 97.541 1.00 29.37 ? 431 LEU B CD2 1 ATOM 9117 N N . TYR B 1 396 ? 77.257 74.249 95.761 1.00 28.27 ? 432 TYR B N 1 ATOM 9118 C CA . TYR B 1 396 ? 78.005 75.181 96.609 1.00 27.47 ? 432 TYR B CA 1 ATOM 9119 C C . TYR B 1 396 ? 77.045 76.135 97.342 1.00 31.66 ? 432 TYR B C 1 ATOM 9120 O O . TYR B 1 396 ? 75.895 76.334 96.925 1.00 26.32 ? 432 TYR B O 1 ATOM 9121 C CB . TYR B 1 396 ? 79.008 76.008 95.786 1.00 28.13 ? 432 TYR B CB 1 ATOM 9122 C CG . TYR B 1 396 ? 80.091 75.210 95.079 1.00 29.18 ? 432 TYR B CG 1 ATOM 9123 C CD1 . TYR B 1 396 ? 79.799 74.465 93.955 1.00 27.55 ? 432 TYR B CD1 1 ATOM 9124 C CD2 . TYR B 1 396 ? 81.406 75.209 95.540 1.00 31.34 ? 432 TYR B CD2 1 ATOM 9125 C CE1 . TYR B 1 396 ? 80.779 73.731 93.288 1.00 29.54 ? 432 TYR B CE1 1 ATOM 9126 C CE2 . TYR B 1 396 ? 82.398 74.479 94.888 1.00 34.33 ? 432 TYR B CE2 1 ATOM 9127 C CZ . TYR B 1 396 ? 82.072 73.738 93.753 1.00 35.20 ? 432 TYR B CZ 1 ATOM 9128 O OH . TYR B 1 396 ? 83.035 73.002 93.086 1.00 34.97 ? 432 TYR B OH 1 ATOM 9129 N N . LYS B 1 397 ? 77.516 76.708 98.447 1.00 29.05 ? 433 LYS B N 1 ATOM 9130 C CA . LYS B 1 397 ? 76.805 77.813 99.080 1.00 31.93 ? 433 LYS B CA 1 ATOM 9131 C C . LYS B 1 397 ? 77.796 78.940 99.320 1.00 31.87 ? 433 LYS B C 1 ATOM 9132 O O . LYS B 1 397 ? 78.964 78.706 99.616 1.00 32.78 ? 433 LYS B O 1 ATOM 9133 C CB . LYS B 1 397 ? 76.128 77.394 100.388 1.00 31.90 ? 433 LYS B CB 1 ATOM 9134 C CG . LYS B 1 397 ? 77.069 77.151 101.556 1.00 33.12 ? 433 LYS B CG 1 ATOM 9135 C CD . LYS B 1 397 ? 76.266 76.891 102.836 1.00 34.91 ? 433 LYS B CD 1 ATOM 9136 C CE . LYS B 1 397 ? 77.161 76.556 104.038 1.00 36.59 ? 433 LYS B CE 1 ATOM 9137 N NZ . LYS B 1 397 ? 76.324 76.311 105.256 1.00 36.84 ? 433 LYS B NZ 1 ATOM 9138 N N . ILE B 1 398 ? 77.335 80.169 99.156 1.00 32.87 ? 434 ILE B N 1 ATOM 9139 C CA . ILE B 1 398 ? 78.210 81.311 99.326 1.00 29.55 ? 434 ILE B CA 1 ATOM 9140 C C . ILE B 1 398 ? 77.633 82.226 100.403 1.00 29.03 ? 434 ILE B C 1 ATOM 9141 O O . ILE B 1 398 ? 76.453 82.565 100.379 1.00 27.88 ? 434 ILE B O 1 ATOM 9142 C CB . ILE B 1 398 ? 78.423 82.053 97.979 1.00 29.87 ? 434 ILE B CB 1 ATOM 9143 C CG1 . ILE B 1 398 ? 79.368 83.236 98.159 1.00 29.75 ? 434 ILE B CG1 1 ATOM 9144 C CG2 . ILE B 1 398 ? 77.105 82.497 97.401 1.00 30.65 ? 434 ILE B CG2 1 ATOM 9145 C CD1 . ILE B 1 398 ? 79.781 83.883 96.871 1.00 33.46 ? 434 ILE B CD1 1 ATOM 9146 N N . GLN B 1 399 ? 78.470 82.599 101.364 1.00 28.54 ? 435 GLN B N 1 ATOM 9147 C CA . GLN B 1 399 ? 78.019 83.400 102.496 1.00 31.21 ? 435 GLN B CA 1 ATOM 9148 C C . GLN B 1 399 ? 77.766 84.813 102.015 1.00 25.97 ? 435 GLN B C 1 ATOM 9149 O O . GLN B 1 399 ? 78.692 85.487 101.594 1.00 31.07 ? 435 GLN B O 1 ATOM 9150 C CB . GLN B 1 399 ? 79.095 83.403 103.590 1.00 31.45 ? 435 GLN B CB 1 ATOM 9151 C CG . GLN B 1 399 ? 78.642 83.996 104.900 1.00 32.76 ? 435 GLN B CG 1 ATOM 9152 C CD . GLN B 1 399 ? 79.759 83.997 105.940 1.00 40.03 ? 435 GLN B CD 1 ATOM 9153 O OE1 . GLN B 1 399 ? 80.469 82.999 106.110 1.00 32.98 ? 435 GLN B OE1 1 ATOM 9154 N NE2 . GLN B 1 399 ? 79.929 85.124 106.624 1.00 39.24 ? 435 GLN B NE2 1 ATOM 9155 N N . LEU B 1 400 ? 76.517 85.255 102.066 1.00 26.14 ? 436 LEU B N 1 ATOM 9156 C CA . LEU B 1 400 ? 76.147 86.553 101.510 1.00 30.04 ? 436 LEU B CA 1 ATOM 9157 C C . LEU B 1 400 ? 76.762 87.762 102.221 1.00 34.94 ? 436 LEU B C 1 ATOM 9158 O O . LEU B 1 400 ? 76.795 88.867 101.666 1.00 35.59 ? 436 LEU B O 1 ATOM 9159 C CB . LEU B 1 400 ? 74.629 86.686 101.460 1.00 34.28 ? 436 LEU B CB 1 ATOM 9160 C CG . LEU B 1 400 ? 73.996 85.703 100.468 1.00 30.21 ? 436 LEU B CG 1 ATOM 9161 C CD1 . LEU B 1 400 ? 72.501 85.911 100.447 1.00 34.79 ? 436 LEU B CD1 1 ATOM 9162 C CD2 . LEU B 1 400 ? 74.576 85.937 99.090 1.00 25.71 ? 436 LEU B CD2 1 ATOM 9163 N N . SER B 1 401 ? 77.241 87.566 103.445 1.00 34.20 ? 437 SER B N 1 ATOM 9164 C CA . SER B 1 401 ? 77.890 88.664 104.169 1.00 33.64 ? 437 SER B CA 1 ATOM 9165 C C . SER B 1 401 ? 79.414 88.663 103.967 1.00 35.27 ? 437 SER B C 1 ATOM 9166 O O . SER B 1 401 ? 80.105 89.593 104.376 1.00 38.71 ? 437 SER B O 1 ATOM 9167 C CB . SER B 1 401 ? 77.506 88.646 105.658 1.00 37.29 ? 437 SER B CB 1 ATOM 9168 O OG . SER B 1 401 ? 77.970 87.475 106.311 1.00 31.63 ? 437 SER B OG 1 ATOM 9169 N N . ASP B 1 402 ? 79.932 87.623 103.314 1.00 31.26 ? 438 ASP B N 1 ATOM 9170 C CA . ASP B 1 402 ? 81.350 87.565 102.954 1.00 32.14 ? 438 ASP B CA 1 ATOM 9171 C C . ASP B 1 402 ? 81.546 86.636 101.743 1.00 35.30 ? 438 ASP B C 1 ATOM 9172 O O . ASP B 1 402 ? 81.640 85.426 101.915 1.00 30.82 ? 438 ASP B O 1 ATOM 9173 C CB . ASP B 1 402 ? 82.185 87.067 104.138 1.00 30.84 ? 438 ASP B CB 1 ATOM 9174 C CG . ASP B 1 402 ? 83.677 87.090 103.856 1.00 37.72 ? 438 ASP B CG 1 ATOM 9175 O OD1 . ASP B 1 402 ? 84.071 87.354 102.693 1.00 37.63 ? 438 ASP B OD1 1 ATOM 9176 O OD2 . ASP B 1 402 ? 84.459 86.820 104.795 1.00 36.07 ? 438 ASP B OD2 1 ATOM 9177 N N . TYR B 1 403 ? 81.625 87.211 100.539 1.00 30.88 ? 439 TYR B N 1 ATOM 9178 C CA . TYR B 1 403 ? 81.614 86.438 99.289 1.00 30.19 ? 439 TYR B CA 1 ATOM 9179 C C . TYR B 1 403 ? 82.821 85.528 99.141 1.00 36.83 ? 439 TYR B C 1 ATOM 9180 O O . TYR B 1 403 ? 82.847 84.675 98.254 1.00 35.96 ? 439 TYR B O 1 ATOM 9181 C CB . TYR B 1 403 ? 81.569 87.361 98.058 1.00 29.10 ? 439 TYR B CB 1 ATOM 9182 C CG . TYR B 1 403 ? 80.342 88.245 97.939 1.00 32.32 ? 439 TYR B CG 1 ATOM 9183 C CD1 . TYR B 1 403 ? 79.104 87.822 98.405 1.00 30.17 ? 439 TYR B CD1 1 ATOM 9184 C CD2 . TYR B 1 403 ? 80.425 89.505 97.343 1.00 30.69 ? 439 TYR B CD2 1 ATOM 9185 C CE1 . TYR B 1 403 ? 77.983 88.628 98.305 1.00 28.74 ? 439 TYR B CE1 1 ATOM 9186 C CE2 . TYR B 1 403 ? 79.304 90.323 97.241 1.00 32.28 ? 439 TYR B CE2 1 ATOM 9187 C CZ . TYR B 1 403 ? 78.086 89.876 97.719 1.00 31.49 ? 439 TYR B CZ 1 ATOM 9188 O OH . TYR B 1 403 ? 76.962 90.669 97.612 1.00 35.25 ? 439 TYR B OH 1 ATOM 9189 N N . THR B 1 404 ? 83.841 85.724 99.968 1.00 33.03 ? 440 THR B N 1 ATOM 9190 C CA . THR B 1 404 ? 85.037 84.907 99.845 1.00 36.48 ? 440 THR B CA 1 ATOM 9191 C C . THR B 1 404 ? 84.849 83.574 100.583 1.00 37.75 ? 440 THR B C 1 ATOM 9192 O O . THR B 1 404 ? 85.676 82.666 100.480 1.00 40.14 ? 440 THR B O 1 ATOM 9193 C CB . THR B 1 404 ? 86.303 85.637 100.366 1.00 39.21 ? 440 THR B CB 1 ATOM 9194 O OG1 . THR B 1 404 ? 86.158 85.917 101.764 1.00 40.44 ? 440 THR B OG1 1 ATOM 9195 C CG2 . THR B 1 404 ? 86.538 86.944 99.599 1.00 42.05 ? 440 THR B CG2 1 ATOM 9196 N N . LYS B 1 405 ? 83.756 83.462 101.326 1.00 33.70 ? 441 LYS B N 1 ATOM 9197 C CA . LYS B 1 405 ? 83.462 82.229 102.038 1.00 31.23 ? 441 LYS B CA 1 ATOM 9198 C C . LYS B 1 405 ? 82.451 81.383 101.256 1.00 32.10 ? 441 LYS B C 1 ATOM 9199 O O . LYS B 1 405 ? 81.244 81.541 101.395 1.00 32.05 ? 441 LYS B O 1 ATOM 9200 C CB . LYS B 1 405 ? 82.963 82.534 103.451 1.00 40.13 ? 441 LYS B CB 1 ATOM 9201 C CG . LYS B 1 405 ? 83.865 83.511 104.223 1.00 38.58 ? 441 LYS B CG 1 ATOM 9202 C CD . LYS B 1 405 ? 84.667 82.830 105.321 1.00 42.62 ? 441 LYS B CD 1 ATOM 9203 C CE . LYS B 1 405 ? 83.776 82.421 106.485 1.00 46.88 ? 441 LYS B CE 1 ATOM 9204 N N . VAL B 1 406 ? 82.982 80.499 100.422 1.00 33.66 ? 442 VAL B N 1 ATOM 9205 C CA . VAL B 1 406 ? 82.198 79.596 99.594 1.00 32.72 ? 442 VAL B CA 1 ATOM 9206 C C . VAL B 1 406 ? 82.535 78.172 100.014 1.00 35.31 ? 442 VAL B C 1 ATOM 9207 O O . VAL B 1 406 ? 83.706 77.798 100.052 1.00 33.82 ? 442 VAL B O 1 ATOM 9208 C CB . VAL B 1 406 ? 82.573 79.757 98.128 1.00 34.99 ? 442 VAL B CB 1 ATOM 9209 C CG1 . VAL B 1 406 ? 81.883 78.695 97.286 1.00 35.80 ? 442 VAL B CG1 1 ATOM 9210 C CG2 . VAL B 1 406 ? 82.226 81.163 97.632 1.00 31.47 ? 442 VAL B CG2 1 ATOM 9211 N N . THR B 1 407 ? 81.522 77.380 100.341 1.00 32.98 ? 443 THR B N 1 ATOM 9212 C CA . THR B 1 407 ? 81.772 76.007 100.779 1.00 34.71 ? 443 THR B CA 1 ATOM 9213 C C . THR B 1 407 ? 81.116 74.992 99.829 1.00 35.16 ? 443 THR B C 1 ATOM 9214 O O . THR B 1 407 ? 79.953 75.143 99.455 1.00 31.24 ? 443 THR B O 1 ATOM 9215 C CB . THR B 1 407 ? 81.282 75.776 102.227 1.00 33.73 ? 443 THR B CB 1 ATOM 9216 O OG1 . THR B 1 407 ? 79.874 75.556 102.232 1.00 41.55 ? 443 THR B OG1 1 ATOM 9217 C CG2 . THR B 1 407 ? 81.559 76.987 103.075 1.00 30.83 ? 443 THR B CG2 1 ATOM 9218 N N . CYS B 1 408 ? 81.865 73.973 99.425 1.00 31.84 ? 444 CYS B N 1 ATOM 9219 C CA . CYS B 1 408 ? 81.284 72.945 98.572 1.00 31.03 ? 444 CYS B CA 1 ATOM 9220 C C . CYS B 1 408 ? 80.494 71.950 99.408 1.00 32.16 ? 444 CYS B C 1 ATOM 9221 O O . CYS B 1 408 ? 81.028 71.347 100.334 1.00 34.65 ? 444 CYS B O 1 ATOM 9222 C CB . CYS B 1 408 ? 82.349 72.226 97.749 1.00 35.45 ? 444 CYS B CB 1 ATOM 9223 S SG . CYS B 1 408 ? 81.569 71.221 96.437 1.00 35.81 ? 444 CYS B SG 1 ATOM 9224 N N . LEU B 1 409 ? 79.212 71.799 99.100 1.00 29.12 ? 445 LEU B N 1 ATOM 9225 C CA . LEU B 1 409 ? 78.337 70.951 99.892 1.00 28.23 ? 445 LEU B CA 1 ATOM 9226 C C . LEU B 1 409 ? 78.321 69.482 99.432 1.00 34.18 ? 445 LEU B C 1 ATOM 9227 O O . LEU B 1 409 ? 77.902 68.590 100.185 1.00 34.18 ? 445 LEU B O 1 ATOM 9228 C CB . LEU B 1 409 ? 76.907 71.516 99.902 1.00 26.34 ? 445 LEU B CB 1 ATOM 9229 C CG . LEU B 1 409 ? 76.753 72.949 100.432 1.00 28.87 ? 445 LEU B CG 1 ATOM 9230 C CD1 . LEU B 1 409 ? 75.304 73.371 100.449 1.00 31.35 ? 445 LEU B CD1 1 ATOM 9231 C CD2 . LEU B 1 409 ? 77.327 73.057 101.811 1.00 32.50 ? 445 LEU B CD2 1 ATOM 9232 N N . SER B 1 410 ? 78.785 69.227 98.212 1.00 30.72 ? 446 SER B N 1 ATOM 9233 C CA . SER B 1 410 ? 78.627 67.898 97.611 1.00 31.16 ? 446 SER B CA 1 ATOM 9234 C C . SER B 1 410 ? 79.943 67.269 97.161 1.00 31.15 ? 446 SER B C 1 ATOM 9235 O O . SER B 1 410 ? 80.024 66.059 96.986 1.00 35.48 ? 446 SER B O 1 ATOM 9236 C CB . SER B 1 410 ? 77.671 67.979 96.414 1.00 30.68 ? 446 SER B CB 1 ATOM 9237 O OG . SER B 1 410 ? 78.253 68.768 95.397 1.00 27.93 ? 446 SER B OG 1 ATOM 9238 N N . CYS B 1 411 ? 80.967 68.093 96.981 1.00 32.14 ? 447 CYS B N 1 ATOM 9239 C CA . CYS B 1 411 ? 82.242 67.657 96.417 1.00 35.11 ? 447 CYS B CA 1 ATOM 9240 C C . CYS B 1 411 ? 82.805 66.395 97.070 1.00 40.81 ? 447 CYS B C 1 ATOM 9241 O O . CYS B 1 411 ? 83.304 65.497 96.390 1.00 39.14 ? 447 CYS B O 1 ATOM 9242 C CB . CYS B 1 411 ? 83.274 68.784 96.519 1.00 39.24 ? 447 CYS B CB 1 ATOM 9243 S SG . CYS B 1 411 ? 82.974 70.186 95.387 1.00 51.60 ? 447 CYS B SG 1 ATOM 9244 N N . GLU B 1 412 ? 82.723 66.324 98.390 1.00 35.99 ? 448 GLU B N 1 ATOM 9245 C CA . GLU B 1 412 ? 83.415 65.273 99.118 1.00 37.79 ? 448 GLU B CA 1 ATOM 9246 C C . GLU B 1 412 ? 82.499 64.207 99.722 1.00 42.25 ? 448 GLU B C 1 ATOM 9247 O O . GLU B 1 412 ? 82.950 63.368 100.516 1.00 40.00 ? 448 GLU B O 1 ATOM 9248 C CB . GLU B 1 412 ? 84.288 65.903 100.207 1.00 44.52 ? 448 GLU B CB 1 ATOM 9249 C CG . GLU B 1 412 ? 85.294 66.928 99.670 1.00 48.11 ? 448 GLU B CG 1 ATOM 9250 C CD . GLU B 1 412 ? 86.356 66.308 98.777 1.00 54.25 ? 448 GLU B CD 1 ATOM 9251 O OE1 . GLU B 1 412 ? 86.367 65.061 98.633 1.00 56.80 ? 448 GLU B OE1 1 ATOM 9252 O OE2 . GLU B 1 412 ? 87.181 67.067 98.214 1.00 57.54 ? 448 GLU B OE2 1 ATOM 9253 N N . LEU B 1 413 ? 81.220 64.225 99.360 1.00 36.82 ? 449 LEU B N 1 ATOM 9254 C CA . LEU B 1 413 ? 80.287 63.286 99.969 1.00 35.56 ? 449 LEU B CA 1 ATOM 9255 C C . LEU B 1 413 ? 80.634 61.852 99.560 1.00 39.43 ? 449 LEU B C 1 ATOM 9256 O O . LEU B 1 413 ? 80.652 60.938 100.391 1.00 38.98 ? 449 LEU B O 1 ATOM 9257 C CB . LEU B 1 413 ? 78.843 63.632 99.604 1.00 36.44 ? 449 LEU B CB 1 ATOM 9258 C CG . LEU B 1 413 ? 78.278 64.906 100.247 1.00 34.34 ? 449 LEU B CG 1 ATOM 9259 C CD1 . LEU B 1 413 ? 76.866 65.172 99.759 1.00 34.92 ? 449 LEU B CD1 1 ATOM 9260 C CD2 . LEU B 1 413 ? 78.302 64.816 101.757 1.00 37.47 ? 449 LEU B CD2 1 ATOM 9261 N N . ASN B 1 414 ? 80.917 61.673 98.274 1.00 36.71 ? 450 ASN B N 1 ATOM 9262 C CA . ASN B 1 414 ? 81.312 60.381 97.730 1.00 38.17 ? 450 ASN B CA 1 ATOM 9263 C C . ASN B 1 414 ? 82.076 60.660 96.441 1.00 38.45 ? 450 ASN B C 1 ATOM 9264 O O . ASN B 1 414 ? 81.515 60.537 95.355 1.00 39.12 ? 450 ASN B O 1 ATOM 9265 C CB . ASN B 1 414 ? 80.075 59.517 97.434 1.00 36.93 ? 450 ASN B CB 1 ATOM 9266 C CG . ASN B 1 414 ? 79.311 59.113 98.689 1.00 46.47 ? 450 ASN B CG 1 ATOM 9267 O OD1 . ASN B 1 414 ? 79.725 58.205 99.415 1.00 51.15 ? 450 ASN B OD1 1 ATOM 9268 N ND2 . ASN B 1 414 ? 78.172 59.770 98.940 1.00 46.81 ? 450 ASN B ND2 1 ATOM 9269 N N . PRO B 1 415 ? 83.354 61.056 96.554 1.00 36.39 ? 451 PRO B N 1 ATOM 9270 C CA . PRO B 1 415 ? 84.092 61.636 95.423 1.00 38.79 ? 451 PRO B CA 1 ATOM 9271 C C . PRO B 1 415 ? 84.402 60.662 94.285 1.00 40.46 ? 451 PRO B C 1 ATOM 9272 O O . PRO B 1 415 ? 84.713 61.114 93.187 1.00 40.20 ? 451 PRO B O 1 ATOM 9273 C CB . PRO B 1 415 ? 85.397 62.115 96.065 1.00 37.81 ? 451 PRO B CB 1 ATOM 9274 C CG . PRO B 1 415 ? 85.562 61.241 97.270 1.00 43.29 ? 451 PRO B CG 1 ATOM 9275 C CD . PRO B 1 415 ? 84.179 60.966 97.773 1.00 41.26 ? 451 PRO B CD 1 ATOM 9276 N N . GLU B 1 416 ? 84.333 59.362 94.545 1.00 38.45 ? 452 GLU B N 1 ATOM 9277 C CA . GLU B 1 416 ? 84.606 58.366 93.514 1.00 38.36 ? 452 GLU B CA 1 ATOM 9278 C C . GLU B 1 416 ? 83.329 58.057 92.741 1.00 39.30 ? 452 GLU B C 1 ATOM 9279 O O . GLU B 1 416 ? 83.343 57.935 91.507 1.00 37.96 ? 452 GLU B O 1 ATOM 9280 C CB . GLU B 1 416 ? 85.155 57.081 94.142 1.00 40.69 ? 452 GLU B CB 1 ATOM 9281 N N . ARG B 1 417 ? 82.225 57.945 93.474 1.00 31.55 ? 453 ARG B N 1 ATOM 9282 C CA . ARG B 1 417 ? 80.948 57.581 92.877 1.00 33.84 ? 453 ARG B CA 1 ATOM 9283 C C . ARG B 1 417 ? 80.184 58.772 92.299 1.00 36.76 ? 453 ARG B C 1 ATOM 9284 O O . ARG B 1 417 ? 79.475 58.635 91.305 1.00 35.06 ? 453 ARG B O 1 ATOM 9285 C CB . ARG B 1 417 ? 80.084 56.872 93.909 1.00 34.59 ? 453 ARG B CB 1 ATOM 9286 C CG . ARG B 1 417 ? 78.695 56.537 93.424 1.00 29.62 ? 453 ARG B CG 1 ATOM 9287 C CD . ARG B 1 417 ? 77.927 55.788 94.493 1.00 29.85 ? 453 ARG B CD 1 ATOM 9288 N NE . ARG B 1 417 ? 76.576 55.464 94.056 1.00 31.51 ? 453 ARG B NE 1 ATOM 9289 C CZ . ARG B 1 417 ? 75.746 54.662 94.713 1.00 34.29 ? 453 ARG B CZ 1 ATOM 9290 N NH1 . ARG B 1 417 ? 76.128 54.081 95.856 1.00 31.26 ? 453 ARG B NH1 1 ATOM 9291 N NH2 . ARG B 1 417 ? 74.532 54.434 94.227 1.00 30.75 ? 453 ARG B NH2 1 ATOM 9292 N N . CYS B 1 418 ? 80.342 59.943 92.908 1.00 35.07 ? 454 CYS B N 1 ATOM 9293 C CA . CYS B 1 418 ? 79.464 61.068 92.609 1.00 32.55 ? 454 CYS B CA 1 ATOM 9294 C C . CYS B 1 418 ? 80.183 62.356 92.280 1.00 34.62 ? 454 CYS B C 1 ATOM 9295 O O . CYS B 1 418 ? 80.841 62.944 93.140 1.00 33.64 ? 454 CYS B O 1 ATOM 9296 C CB . CYS B 1 418 ? 78.541 61.317 93.785 1.00 32.49 ? 454 CYS B CB 1 ATOM 9297 S SG . CYS B 1 418 ? 77.430 59.955 94.065 1.00 37.82 ? 454 CYS B SG 1 ATOM 9298 N N . GLN B 1 419 ? 80.001 62.807 91.040 1.00 30.40 ? 455 GLN B N 1 ATOM 9299 C CA . GLN B 1 419 ? 80.656 63.996 90.522 1.00 30.59 ? 455 GLN B CA 1 ATOM 9300 C C . GLN B 1 419 ? 79.677 64.869 89.728 1.00 28.35 ? 455 GLN B C 1 ATOM 9301 O O . GLN B 1 419 ? 80.055 65.907 89.204 1.00 31.33 ? 455 GLN B O 1 ATOM 9302 C CB . GLN B 1 419 ? 81.846 63.602 89.630 1.00 32.45 ? 455 GLN B CB 1 ATOM 9303 C CG . GLN B 1 419 ? 83.011 62.942 90.380 1.00 34.57 ? 455 GLN B CG 1 ATOM 9304 C CD . GLN B 1 419 ? 83.967 62.150 89.471 1.00 41.33 ? 455 GLN B CD 1 ATOM 9305 O OE1 . GLN B 1 419 ? 84.128 62.448 88.283 1.00 37.38 ? 455 GLN B OE1 1 ATOM 9306 N NE2 . GLN B 1 419 ? 84.600 61.129 90.039 1.00 44.15 ? 455 GLN B NE2 1 ATOM 9307 N N . TYR B 1 420 ? 78.419 64.450 89.646 1.00 31.73 ? 456 TYR B N 1 ATOM 9308 C CA . TYR B 1 420 ? 77.430 65.169 88.841 1.00 29.76 ? 456 TYR B CA 1 ATOM 9309 C C . TYR B 1 420 ? 76.149 65.277 89.629 1.00 31.38 ? 456 TYR B C 1 ATOM 9310 O O . TYR B 1 420 ? 75.352 64.339 89.647 1.00 30.00 ? 456 TYR B O 1 ATOM 9311 C CB . TYR B 1 420 ? 77.141 64.427 87.538 1.00 26.48 ? 456 TYR B CB 1 ATOM 9312 C CG . TYR B 1 420 ? 76.580 65.306 86.433 1.00 27.25 ? 456 TYR B CG 1 ATOM 9313 C CD1 . TYR B 1 420 ? 75.232 65.639 86.381 1.00 27.31 ? 456 TYR B CD1 1 ATOM 9314 C CD2 . TYR B 1 420 ? 77.402 65.788 85.437 1.00 27.11 ? 456 TYR B CD2 1 ATOM 9315 C CE1 . TYR B 1 420 ? 74.728 66.433 85.364 1.00 28.77 ? 456 TYR B CE1 1 ATOM 9316 C CE2 . TYR B 1 420 ? 76.908 66.565 84.412 1.00 29.70 ? 456 TYR B CE2 1 ATOM 9317 C CZ . TYR B 1 420 ? 75.577 66.886 84.381 1.00 31.71 ? 456 TYR B CZ 1 ATOM 9318 O OH . TYR B 1 420 ? 75.115 67.678 83.355 1.00 35.06 ? 456 TYR B OH 1 ATOM 9319 N N . TYR B 1 421 ? 75.947 66.424 90.272 1.00 27.65 ? 457 TYR B N 1 ATOM 9320 C CA . TYR B 1 421 ? 74.820 66.592 91.177 1.00 26.52 ? 457 TYR B CA 1 ATOM 9321 C C . TYR B 1 421 ? 73.781 67.548 90.633 1.00 27.97 ? 457 TYR B C 1 ATOM 9322 O O . TYR B 1 421 ? 74.111 68.504 89.935 1.00 28.68 ? 457 TYR B O 1 ATOM 9323 C CB . TYR B 1 421 ? 75.317 67.152 92.503 1.00 27.60 ? 457 TYR B CB 1 ATOM 9324 C CG . TYR B 1 421 ? 76.013 66.152 93.391 1.00 27.07 ? 457 TYR B CG 1 ATOM 9325 C CD1 . TYR B 1 421 ? 77.394 65.992 93.353 1.00 26.96 ? 457 TYR B CD1 1 ATOM 9326 C CD2 . TYR B 1 421 ? 75.290 65.388 94.292 1.00 26.78 ? 457 TYR B CD2 1 ATOM 9327 C CE1 . TYR B 1 421 ? 78.028 65.084 94.192 1.00 28.73 ? 457 TYR B CE1 1 ATOM 9328 C CE2 . TYR B 1 421 ? 75.913 64.488 95.128 1.00 28.71 ? 457 TYR B CE2 1 ATOM 9329 C CZ . TYR B 1 421 ? 77.278 64.339 95.077 1.00 30.10 ? 457 TYR B CZ 1 ATOM 9330 O OH . TYR B 1 421 ? 77.887 63.432 95.922 1.00 32.11 ? 457 TYR B OH 1 ATOM 9331 N N . SER B 1 422 ? 72.527 67.286 90.962 1.00 26.64 ? 458 SER B N 1 ATOM 9332 C CA . SER B 1 422 ? 71.497 68.307 90.899 1.00 30.37 ? 458 SER B CA 1 ATOM 9333 C C . SER B 1 422 ? 70.839 68.314 92.277 1.00 32.01 ? 458 SER B C 1 ATOM 9334 O O . SER B 1 422 ? 71.153 67.461 93.118 1.00 27.85 ? 458 SER B O 1 ATOM 9335 C CB . SER B 1 422 ? 70.487 68.014 89.796 1.00 30.83 ? 458 SER B CB 1 ATOM 9336 O OG . SER B 1 422 ? 69.656 66.922 90.139 1.00 35.73 ? 458 SER B OG 1 ATOM 9337 N N . VAL B 1 423 ? 69.935 69.260 92.522 1.00 30.06 ? 459 VAL B N 1 ATOM 9338 C CA . VAL B 1 423 ? 69.407 69.441 93.872 1.00 27.95 ? 459 VAL B CA 1 ATOM 9339 C C . VAL B 1 423 ? 67.963 69.933 93.885 1.00 29.54 ? 459 VAL B C 1 ATOM 9340 O O . VAL B 1 423 ? 67.490 70.554 92.928 1.00 25.42 ? 459 VAL B O 1 ATOM 9341 C CB . VAL B 1 423 ? 70.269 70.445 94.658 1.00 29.49 ? 459 VAL B CB 1 ATOM 9342 C CG1 . VAL B 1 423 ? 70.124 71.826 94.054 1.00 24.02 ? 459 VAL B CG1 1 ATOM 9343 C CG2 . VAL B 1 423 ? 69.882 70.450 96.155 1.00 25.38 ? 459 VAL B CG2 1 ATOM 9344 N N . SER B 1 424 ? 67.268 69.652 94.981 1.00 27.13 ? 460 SER B N 1 ATOM 9345 C CA . SER B 1 424 ? 65.906 70.148 95.188 1.00 26.41 ? 460 SER B CA 1 ATOM 9346 C C . SER B 1 424 ? 65.679 70.551 96.657 1.00 32.41 ? 460 SER B C 1 ATOM 9347 O O . SER B 1 424 ? 65.669 69.701 97.556 1.00 29.84 ? 460 SER B O 1 ATOM 9348 C CB . SER B 1 424 ? 64.903 69.084 94.755 1.00 28.34 ? 460 SER B CB 1 ATOM 9349 O OG . SER B 1 424 ? 63.589 69.438 95.129 1.00 30.30 ? 460 SER B OG 1 ATOM 9350 N N . PHE B 1 425 ? 65.507 71.853 96.886 1.00 27.24 ? 461 PHE B N 1 ATOM 9351 C CA . PHE B 1 425 ? 65.348 72.429 98.222 1.00 29.91 ? 461 PHE B CA 1 ATOM 9352 C C . PHE B 1 425 ? 63.876 72.488 98.626 1.00 30.18 ? 461 PHE B C 1 ATOM 9353 O O . PHE B 1 425 ? 63.011 72.738 97.797 1.00 27.17 ? 461 PHE B O 1 ATOM 9354 C CB . PHE B 1 425 ? 65.900 73.866 98.244 1.00 26.36 ? 461 PHE B CB 1 ATOM 9355 C CG . PHE B 1 425 ? 67.398 73.947 98.347 1.00 28.71 ? 461 PHE B CG 1 ATOM 9356 C CD1 . PHE B 1 425 ? 68.186 73.878 97.217 1.00 28.68 ? 461 PHE B CD1 1 ATOM 9357 C CD2 . PHE B 1 425 ? 68.014 74.081 99.575 1.00 25.98 ? 461 PHE B CD2 1 ATOM 9358 C CE1 . PHE B 1 425 ? 69.569 73.945 97.312 1.00 29.96 ? 461 PHE B CE1 1 ATOM 9359 C CE2 . PHE B 1 425 ? 69.384 74.143 99.680 1.00 26.33 ? 461 PHE B CE2 1 ATOM 9360 C CZ . PHE B 1 425 ? 70.164 74.084 98.545 1.00 27.98 ? 461 PHE B CZ 1 ATOM 9361 N N . SER B 1 426 ? 63.576 72.292 99.905 1.00 28.43 ? 462 SER B N 1 ATOM 9362 C CA . SER B 1 426 ? 62.200 72.512 100.355 1.00 29.91 ? 462 SER B CA 1 ATOM 9363 C C . SER B 1 426 ? 61.934 74.019 100.387 1.00 30.36 ? 462 SER B C 1 ATOM 9364 O O . SER B 1 426 ? 62.850 74.808 100.152 1.00 29.94 ? 462 SER B O 1 ATOM 9365 C CB . SER B 1 426 ? 61.960 71.886 101.724 1.00 32.39 ? 462 SER B CB 1 ATOM 9366 O OG . SER B 1 426 ? 62.508 72.689 102.735 1.00 29.85 ? 462 SER B OG 1 ATOM 9367 N N . LYS B 1 427 ? 60.694 74.424 100.646 1.00 35.11 ? 463 LYS B N 1 ATOM 9368 C CA . LYS B 1 427 ? 60.357 75.853 100.655 1.00 40.05 ? 463 LYS B CA 1 ATOM 9369 C C . LYS B 1 427 ? 61.179 76.521 101.743 1.00 39.37 ? 463 LYS B C 1 ATOM 9370 O O . LYS B 1 427 ? 61.295 75.993 102.840 1.00 44.95 ? 463 LYS B O 1 ATOM 9371 C CB . LYS B 1 427 ? 58.864 76.073 100.935 1.00 39.92 ? 463 LYS B CB 1 ATOM 9372 C CG . LYS B 1 427 ? 57.922 75.112 100.209 1.00 38.28 ? 463 LYS B CG 1 ATOM 9373 C CD . LYS B 1 427 ? 57.995 75.263 98.696 1.00 47.31 ? 463 LYS B CD 1 ATOM 9374 N N . GLU B 1 428 ? 61.769 77.667 101.455 1.00 41.50 ? 464 GLU B N 1 ATOM 9375 C CA . GLU B 1 428 ? 62.591 78.346 102.458 1.00 39.20 ? 464 GLU B CA 1 ATOM 9376 C C . GLU B 1 428 ? 63.911 77.635 102.755 1.00 35.05 ? 464 GLU B C 1 ATOM 9377 O O . GLU B 1 428 ? 64.619 78.014 103.673 1.00 29.24 ? 464 GLU B O 1 ATOM 9378 C CB . GLU B 1 428 ? 61.816 78.553 103.755 1.00 42.92 ? 464 GLU B CB 1 ATOM 9379 C CG . GLU B 1 428 ? 60.514 79.330 103.604 1.00 46.60 ? 464 GLU B CG 1 ATOM 9380 C CD . GLU B 1 428 ? 59.850 79.582 104.955 1.00 60.36 ? 464 GLU B CD 1 ATOM 9381 O OE1 . GLU B 1 428 ? 60.582 79.866 105.934 1.00 62.51 ? 464 GLU B OE1 1 ATOM 9382 O OE2 . GLU B 1 428 ? 58.603 79.481 105.047 1.00 64.08 ? 464 GLU B OE2 1 ATOM 9383 N N . ALA B 1 429 ? 64.236 76.604 101.979 1.00 34.27 ? 465 ALA B N 1 ATOM 9384 C CA . ALA B 1 429 ? 65.582 76.021 101.996 1.00 32.63 ? 465 ALA B CA 1 ATOM 9385 C C . ALA B 1 429 ? 66.047 75.396 103.321 1.00 30.53 ? 465 ALA B C 1 ATOM 9386 O O . ALA B 1 429 ? 67.252 75.327 103.599 1.00 31.88 ? 465 ALA B O 1 ATOM 9387 C CB . ALA B 1 429 ? 66.610 77.036 101.498 1.00 30.72 ? 465 ALA B CB 1 ATOM 9388 N N . LYS B 1 430 ? 65.103 74.912 104.116 1.00 30.60 ? 466 LYS B N 1 ATOM 9389 C CA . LYS B 1 430 ? 65.439 74.200 105.342 1.00 35.84 ? 466 LYS B CA 1 ATOM 9390 C C . LYS B 1 430 ? 66.154 72.868 105.057 1.00 33.01 ? 466 LYS B C 1 ATOM 9391 O O . LYS B 1 430 ? 67.149 72.534 105.707 1.00 34.83 ? 466 LYS B O 1 ATOM 9392 C CB . LYS B 1 430 ? 64.180 73.983 106.178 1.00 34.72 ? 466 LYS B CB 1 ATOM 9393 C CG . LYS B 1 430 ? 64.431 73.781 107.665 1.00 42.24 ? 466 LYS B CG 1 ATOM 9394 C CD . LYS B 1 430 ? 63.099 73.676 108.426 1.00 44.44 ? 466 LYS B CD 1 ATOM 9395 C CE . LYS B 1 430 ? 63.257 73.019 109.790 1.00 45.02 ? 466 LYS B CE 1 ATOM 9396 N NZ . LYS B 1 430 ? 64.184 73.785 110.673 1.00 48.09 ? 466 LYS B NZ 1 ATOM 9397 N N . TYR B 1 431 ? 65.664 72.122 104.075 1.00 30.03 ? 467 TYR B N 1 ATOM 9398 C CA . TYR B 1 431 ? 66.270 70.840 103.701 1.00 31.78 ? 467 TYR B CA 1 ATOM 9399 C C . TYR B 1 431 ? 66.550 70.791 102.219 1.00 31.11 ? 467 TYR B C 1 ATOM 9400 O O . TYR B 1 431 ? 65.958 71.542 101.443 1.00 30.22 ? 467 TYR B O 1 ATOM 9401 C CB . TYR B 1 431 ? 65.337 69.677 104.066 1.00 31.19 ? 467 TYR B CB 1 ATOM 9402 C CG . TYR B 1 431 ? 64.940 69.676 105.524 1.00 32.61 ? 467 TYR B CG 1 ATOM 9403 C CD1 . TYR B 1 431 ? 65.712 69.015 106.476 1.00 34.44 ? 467 TYR B CD1 1 ATOM 9404 C CD2 . TYR B 1 431 ? 63.804 70.346 105.949 1.00 33.21 ? 467 TYR B CD2 1 ATOM 9405 C CE1 . TYR B 1 431 ? 65.365 69.033 107.811 1.00 35.97 ? 467 TYR B CE1 1 ATOM 9406 C CE2 . TYR B 1 431 ? 63.443 70.362 107.281 1.00 36.89 ? 467 TYR B CE2 1 ATOM 9407 C CZ . TYR B 1 431 ? 64.227 69.706 108.210 1.00 36.40 ? 467 TYR B CZ 1 ATOM 9408 O OH . TYR B 1 431 ? 63.865 69.728 109.538 1.00 38.82 ? 467 TYR B OH 1 ATOM 9409 N N . TYR B 1 432 ? 67.443 69.899 101.805 1.00 28.97 ? 468 TYR B N 1 ATOM 9410 C CA . TYR B 1 432 ? 67.613 69.664 100.373 1.00 30.77 ? 468 TYR B CA 1 ATOM 9411 C C . TYR B 1 432 ? 67.869 68.200 100.041 1.00 32.17 ? 468 TYR B C 1 ATOM 9412 O O . TYR B 1 432 ? 68.545 67.496 100.794 1.00 32.46 ? 468 TYR B O 1 ATOM 9413 C CB . TYR B 1 432 ? 68.704 70.567 99.777 1.00 27.40 ? 468 TYR B CB 1 ATOM 9414 C CG . TYR B 1 432 ? 70.044 70.512 100.478 1.00 29.90 ? 468 TYR B CG 1 ATOM 9415 C CD1 . TYR B 1 432 ? 70.291 71.292 101.592 1.00 28.41 ? 468 TYR B CD1 1 ATOM 9416 C CD2 . TYR B 1 432 ? 71.073 69.715 99.999 1.00 29.67 ? 468 TYR B CD2 1 ATOM 9417 C CE1 . TYR B 1 432 ? 71.525 71.271 102.235 1.00 28.59 ? 468 TYR B CE1 1 ATOM 9418 C CE2 . TYR B 1 432 ? 72.310 69.686 100.631 1.00 30.37 ? 468 TYR B CE2 1 ATOM 9419 C CZ . TYR B 1 432 ? 72.526 70.465 101.756 1.00 33.56 ? 468 TYR B CZ 1 ATOM 9420 O OH . TYR B 1 432 ? 73.751 70.450 102.396 1.00 36.32 ? 468 TYR B OH 1 ATOM 9421 N N . GLN B 1 433 ? 67.291 67.741 98.932 1.00 27.23 ? 469 GLN B N 1 ATOM 9422 C CA . GLN B 1 433 ? 67.618 66.440 98.355 1.00 28.84 ? 469 GLN B CA 1 ATOM 9423 C C . GLN B 1 433 ? 68.736 66.577 97.321 1.00 30.40 ? 469 GLN B C 1 ATOM 9424 O O . GLN B 1 433 ? 68.641 67.383 96.384 1.00 27.75 ? 469 GLN B O 1 ATOM 9425 C CB . GLN B 1 433 ? 66.386 65.837 97.686 1.00 30.37 ? 469 GLN B CB 1 ATOM 9426 C CG . GLN B 1 433 ? 66.617 64.469 97.049 1.00 28.94 ? 469 GLN B CG 1 ATOM 9427 C CD . GLN B 1 433 ? 65.622 64.177 95.942 1.00 35.80 ? 469 GLN B CD 1 ATOM 9428 O OE1 . GLN B 1 433 ? 65.255 65.071 95.176 1.00 31.63 ? 469 GLN B OE1 1 ATOM 9429 N NE2 . GLN B 1 433 ? 65.174 62.922 95.853 1.00 33.47 ? 469 GLN B NE2 1 ATOM 9430 N N . LEU B 1 434 ? 69.804 65.804 97.487 1.00 23.74 ? 470 LEU B N 1 ATOM 9431 C CA . LEU B 1 434 ? 70.855 65.753 96.479 1.00 28.61 ? 470 LEU B CA 1 ATOM 9432 C C . LEU B 1 434 ? 70.642 64.548 95.556 1.00 31.44 ? 470 LEU B C 1 ATOM 9433 O O . LEU B 1 434 ? 70.277 63.456 96.008 1.00 33.17 ? 470 LEU B O 1 ATOM 9434 C CB . LEU B 1 434 ? 72.251 65.712 97.114 1.00 27.27 ? 470 LEU B CB 1 ATOM 9435 C CG . LEU B 1 434 ? 72.832 67.066 97.537 1.00 28.06 ? 470 LEU B CG 1 ATOM 9436 C CD1 . LEU B 1 434 ? 74.148 66.890 98.273 1.00 27.92 ? 470 LEU B CD1 1 ATOM 9437 C CD2 . LEU B 1 434 ? 73.021 67.976 96.322 1.00 27.10 ? 470 LEU B CD2 1 ATOM 9438 N N . ARG B 1 435 ? 70.862 64.764 94.268 1.00 28.90 ? 471 ARG B N 1 ATOM 9439 C CA . ARG B 1 435 ? 70.711 63.726 93.256 1.00 29.27 ? 471 ARG B CA 1 ATOM 9440 C C . ARG B 1 435 ? 72.026 63.593 92.507 1.00 32.45 ? 471 ARG B C 1 ATOM 9441 O O . ARG B 1 435 ? 72.397 64.477 91.738 1.00 33.08 ? 471 ARG B O 1 ATOM 9442 C CB . ARG B 1 435 ? 69.592 64.108 92.285 1.00 33.10 ? 471 ARG B CB 1 ATOM 9443 C CG . ARG B 1 435 ? 69.458 63.170 91.086 1.00 40.99 ? 471 ARG B CG 1 ATOM 9444 N N . CYS B 1 436 ? 72.738 62.497 92.751 1.00 32.50 ? 472 CYS B N 1 ATOM 9445 C CA . CYS B 1 436 ? 73.997 62.192 92.063 1.00 33.23 ? 472 CYS B CA 1 ATOM 9446 C C . CYS B 1 436 ? 73.659 61.362 90.832 1.00 31.26 ? 472 CYS B C 1 ATOM 9447 O O . CYS B 1 436 ? 72.914 60.395 90.955 1.00 32.89 ? 472 CYS B O 1 ATOM 9448 C CB . CYS B 1 436 ? 74.912 61.403 93.018 1.00 35.84 ? 472 CYS B CB 1 ATOM 9449 S SG . CYS B 1 436 ? 76.409 60.569 92.340 1.00 43.20 ? 472 CYS B SG 1 ATOM 9450 N N . SER B 1 437 ? 74.170 61.756 89.660 1.00 31.77 ? 473 SER B N 1 ATOM 9451 C CA . SER B 1 437 ? 73.894 61.068 88.386 1.00 30.11 ? 473 SER B CA 1 ATOM 9452 C C . SER B 1 437 ? 75.072 60.272 87.836 1.00 33.97 ? 473 SER B C 1 ATOM 9453 O O . SER B 1 437 ? 74.968 59.648 86.775 1.00 30.93 ? 473 SER B O 1 ATOM 9454 C CB . SER B 1 437 ? 73.470 62.073 87.308 1.00 32.22 ? 473 SER B CB 1 ATOM 9455 O OG . SER B 1 437 ? 72.150 62.526 87.541 1.00 39.85 ? 473 SER B OG 1 ATOM 9456 N N . GLY B 1 438 ? 76.207 60.311 88.518 1.00 28.95 ? 474 GLY B N 1 ATOM 9457 C CA . GLY B 1 438 ? 77.364 59.577 88.035 1.00 32.38 ? 474 GLY B CA 1 ATOM 9458 C C . GLY B 1 438 ? 78.640 60.129 88.617 1.00 32.68 ? 474 GLY B C 1 ATOM 9459 O O . GLY B 1 438 ? 78.602 61.129 89.334 1.00 32.20 ? 474 GLY B O 1 ATOM 9460 N N . PRO B 1 439 ? 79.782 59.516 88.282 1.00 33.00 ? 475 PRO B N 1 ATOM 9461 C CA . PRO B 1 439 ? 79.941 58.417 87.309 1.00 29.75 ? 475 PRO B CA 1 ATOM 9462 C C . PRO B 1 439 ? 79.484 57.030 87.803 1.00 32.82 ? 475 PRO B C 1 ATOM 9463 O O . PRO B 1 439 ? 79.363 56.112 86.990 1.00 36.07 ? 475 PRO B O 1 ATOM 9464 C CB . PRO B 1 439 ? 81.448 58.414 87.034 1.00 31.41 ? 475 PRO B CB 1 ATOM 9465 C CG . PRO B 1 439 ? 82.066 58.969 88.295 1.00 35.39 ? 475 PRO B CG 1 ATOM 9466 C CD . PRO B 1 439 ? 81.071 59.956 88.852 1.00 31.91 ? 475 PRO B CD 1 ATOM 9467 N N . GLY B 1 440 ? 79.233 56.885 89.101 1.00 33.58 ? 476 GLY B N 1 ATOM 9468 C CA . GLY B 1 440 ? 78.748 55.630 89.662 1.00 33.88 ? 476 GLY B CA 1 ATOM 9469 C C . GLY B 1 440 ? 77.244 55.572 89.515 1.00 32.98 ? 476 GLY B C 1 ATOM 9470 O O . GLY B 1 440 ? 76.657 56.453 88.900 1.00 34.68 ? 476 GLY B O 1 ATOM 9471 N N . LEU B 1 441 ? 76.606 54.551 90.068 1.00 28.16 ? 477 LEU B N 1 ATOM 9472 C CA . LEU B 1 441 ? 75.154 54.496 90.009 1.00 33.68 ? 477 LEU B CA 1 ATOM 9473 C C . LEU B 1 441 ? 74.557 55.702 90.738 1.00 34.88 ? 477 LEU B C 1 ATOM 9474 O O . LEU B 1 441 ? 75.067 56.113 91.777 1.00 33.23 ? 477 LEU B O 1 ATOM 9475 C CB . LEU B 1 441 ? 74.640 53.192 90.622 1.00 33.71 ? 477 LEU B CB 1 ATOM 9476 C CG . LEU B 1 441 ? 75.183 51.906 89.995 1.00 36.36 ? 477 LEU B CG 1 ATOM 9477 C CD1 . LEU B 1 441 ? 74.459 50.697 90.568 1.00 35.93 ? 477 LEU B CD1 1 ATOM 9478 C CD2 . LEU B 1 441 ? 75.033 51.953 88.489 1.00 35.39 ? 477 LEU B CD2 1 ATOM 9479 N N . PRO B 1 442 ? 73.470 56.271 90.196 1.00 35.43 ? 478 PRO B N 1 ATOM 9480 C CA . PRO B 1 442 ? 72.789 57.409 90.828 1.00 34.06 ? 478 PRO B CA 1 ATOM 9481 C C . PRO B 1 442 ? 72.452 57.186 92.307 1.00 33.45 ? 478 PRO B C 1 ATOM 9482 O O . PRO B 1 442 ? 71.964 56.119 92.690 1.00 31.82 ? 478 PRO B O 1 ATOM 9483 C CB . PRO B 1 442 ? 71.506 57.541 90.005 1.00 32.74 ? 478 PRO B CB 1 ATOM 9484 C CG . PRO B 1 442 ? 71.912 57.067 88.642 1.00 35.82 ? 478 PRO B CG 1 ATOM 9485 C CD . PRO B 1 442 ? 72.843 55.902 88.914 1.00 37.47 ? 478 PRO B CD 1 ATOM 9486 N N . LEU B 1 443 ? 72.700 58.207 93.123 1.00 30.41 ? 479 LEU B N 1 ATOM 9487 C CA . LEU B 1 443 ? 72.500 58.111 94.566 1.00 31.33 ? 479 LEU B CA 1 ATOM 9488 C C . LEU B 1 443 ? 71.723 59.338 95.039 1.00 31.67 ? 479 LEU B C 1 ATOM 9489 O O . LEU B 1 443 ? 72.143 60.478 94.784 1.00 28.40 ? 479 LEU B O 1 ATOM 9490 C CB . LEU B 1 443 ? 73.849 58.022 95.289 1.00 30.58 ? 479 LEU B CB 1 ATOM 9491 C CG . LEU B 1 443 ? 73.820 58.112 96.824 1.00 32.39 ? 479 LEU B CG 1 ATOM 9492 C CD1 . LEU B 1 443 ? 73.087 56.920 97.433 1.00 27.59 ? 479 LEU B CD1 1 ATOM 9493 C CD2 . LEU B 1 443 ? 75.226 58.213 97.410 1.00 30.47 ? 479 LEU B CD2 1 ATOM 9494 N N . TYR B 1 444 ? 70.588 59.099 95.695 1.00 21.98 ? 480 TYR B N 1 ATOM 9495 C CA . TYR B 1 444 ? 69.727 60.168 96.193 1.00 30.61 ? 480 TYR B CA 1 ATOM 9496 C C . TYR B 1 444 ? 69.813 60.276 97.720 1.00 31.04 ? 480 TYR B C 1 ATOM 9497 O O . TYR B 1 444 ? 69.558 59.303 98.442 1.00 30.61 ? 480 TYR B O 1 ATOM 9498 C CB . TYR B 1 444 ? 68.276 59.920 95.768 1.00 29.02 ? 480 TYR B CB 1 ATOM 9499 C CG . TYR B 1 444 ? 68.082 59.807 94.267 1.00 33.05 ? 480 TYR B CG 1 ATOM 9500 C CD1 . TYR B 1 444 ? 68.471 58.665 93.581 1.00 28.54 ? 480 TYR B CD1 1 ATOM 9501 C CD2 . TYR B 1 444 ? 67.495 60.844 93.540 1.00 32.70 ? 480 TYR B CD2 1 ATOM 9502 C CE1 . TYR B 1 444 ? 68.291 58.558 92.205 1.00 34.61 ? 480 TYR B CE1 1 ATOM 9503 C CE2 . TYR B 1 444 ? 67.303 60.742 92.178 1.00 33.11 ? 480 TYR B CE2 1 ATOM 9504 C CZ . TYR B 1 444 ? 67.704 59.599 91.515 1.00 38.17 ? 480 TYR B CZ 1 ATOM 9505 O OH . TYR B 1 444 ? 67.531 59.503 90.158 1.00 38.20 ? 480 TYR B OH 1 ATOM 9506 N N . THR B 1 445 ? 70.164 61.461 98.208 1.00 30.56 ? 481 THR B N 1 ATOM 9507 C CA . THR B 1 445 ? 70.403 61.674 99.635 1.00 27.08 ? 481 THR B CA 1 ATOM 9508 C C . THR B 1 445 ? 69.612 62.887 100.133 1.00 30.60 ? 481 THR B C 1 ATOM 9509 O O . THR B 1 445 ? 69.302 63.798 99.350 1.00 27.93 ? 481 THR B O 1 ATOM 9510 C CB . THR B 1 445 ? 71.909 61.903 99.912 1.00 32.94 ? 481 THR B CB 1 ATOM 9511 O OG1 . THR B 1 445 ? 72.411 62.937 99.047 1.00 30.04 ? 481 THR B OG1 1 ATOM 9512 C CG2 . THR B 1 445 ? 72.702 60.626 99.665 1.00 31.83 ? 481 THR B CG2 1 ATOM 9513 N N . LEU B 1 446 ? 69.285 62.906 101.423 1.00 26.67 ? 482 LEU B N 1 ATOM 9514 C CA . LEU B 1 446 ? 68.596 64.052 102.008 1.00 26.51 ? 482 LEU B CA 1 ATOM 9515 C C . LEU B 1 446 ? 69.466 64.728 103.076 1.00 36.07 ? 482 LEU B C 1 ATOM 9516 O O . LEU B 1 446 ? 70.180 64.049 103.832 1.00 31.20 ? 482 LEU B O 1 ATOM 9517 C CB . LEU B 1 446 ? 67.252 63.633 102.597 1.00 29.44 ? 482 LEU B CB 1 ATOM 9518 C CG . LEU B 1 446 ? 66.238 64.727 102.937 1.00 34.12 ? 482 LEU B CG 1 ATOM 9519 C CD1 . LEU B 1 446 ? 65.582 65.279 101.669 1.00 28.14 ? 482 LEU B CD1 1 ATOM 9520 C CD2 . LEU B 1 446 ? 65.168 64.217 103.899 1.00 29.29 ? 482 LEU B CD2 1 ATOM 9521 N N . HIS B 1 447 ? 69.402 66.061 103.134 1.00 29.16 ? 483 HIS B N 1 ATOM 9522 C CA . HIS B 1 447 ? 70.290 66.848 103.982 1.00 32.03 ? 483 HIS B CA 1 ATOM 9523 C C . HIS B 1 447 ? 69.517 67.999 104.618 1.00 32.59 ? 483 HIS B C 1 ATOM 9524 O O . HIS B 1 447 ? 68.472 68.404 104.109 1.00 28.35 ? 483 HIS B O 1 ATOM 9525 C CB . HIS B 1 447 ? 71.463 67.403 103.161 1.00 29.39 ? 483 HIS B CB 1 ATOM 9526 C CG . HIS B 1 447 ? 72.188 66.361 102.368 1.00 32.27 ? 483 HIS B CG 1 ATOM 9527 N ND1 . HIS B 1 447 ? 73.468 65.955 102.670 1.00 34.27 ? 483 HIS B ND1 1 ATOM 9528 C CD2 . HIS B 1 447 ? 71.806 65.638 101.286 1.00 32.81 ? 483 HIS B CD2 1 ATOM 9529 C CE1 . HIS B 1 447 ? 73.845 65.023 101.810 1.00 33.49 ? 483 HIS B CE1 1 ATOM 9530 N NE2 . HIS B 1 447 ? 72.854 64.812 100.960 1.00 33.41 ? 483 HIS B NE2 1 ATOM 9531 N N . SER B 1 448 ? 70.023 68.503 105.740 1.00 30.72 ? 484 SER B N 1 ATOM 9532 C CA . SER B 1 448 ? 69.437 69.668 106.396 1.00 31.87 ? 484 SER B CA 1 ATOM 9533 C C . SER B 1 448 ? 70.416 70.835 106.283 1.00 30.03 ? 484 SER B C 1 ATOM 9534 O O . SER B 1 448 ? 71.607 70.679 106.500 1.00 33.29 ? 484 SER B O 1 ATOM 9535 C CB . SER B 1 448 ? 69.116 69.378 107.861 1.00 36.94 ? 484 SER B CB 1 ATOM 9536 O OG . SER B 1 448 ? 70.306 69.194 108.591 1.00 41.38 ? 484 SER B OG 1 ATOM 9537 N N . SER B 1 449 ? 69.909 72.002 105.915 1.00 29.98 ? 485 SER B N 1 ATOM 9538 C CA . SER B 1 449 ? 70.770 73.136 105.591 1.00 33.07 ? 485 SER B CA 1 ATOM 9539 C C . SER B 1 449 ? 71.436 73.769 106.818 1.00 36.96 ? 485 SER B C 1 ATOM 9540 O O . SER B 1 449 ? 72.508 74.364 106.710 1.00 33.75 ? 485 SER B O 1 ATOM 9541 C CB . SER B 1 449 ? 69.956 74.200 104.853 1.00 34.96 ? 485 SER B CB 1 ATOM 9542 O OG . SER B 1 449 ? 69.332 73.634 103.699 1.00 34.40 ? 485 SER B OG 1 ATOM 9543 N N . VAL B 1 450 ? 70.810 73.643 107.982 1.00 33.75 ? 486 VAL B N 1 ATOM 9544 C CA . VAL B 1 450 ? 71.287 74.406 109.139 1.00 39.32 ? 486 VAL B CA 1 ATOM 9545 C C . VAL B 1 450 ? 72.777 74.188 109.394 1.00 39.22 ? 486 VAL B C 1 ATOM 9546 O O . VAL B 1 450 ? 73.515 75.145 109.623 1.00 44.12 ? 486 VAL B O 1 ATOM 9547 C CB . VAL B 1 450 ? 70.455 74.145 110.406 1.00 40.29 ? 486 VAL B CB 1 ATOM 9548 C CG1 . VAL B 1 450 ? 70.789 72.789 110.993 1.00 40.89 ? 486 VAL B CG1 1 ATOM 9549 C CG2 . VAL B 1 450 ? 70.697 75.257 111.424 1.00 51.02 ? 486 VAL B CG2 1 ATOM 9550 N N . ASN B 1 451 ? 73.219 72.934 109.337 1.00 39.95 ? 487 ASN B N 1 ATOM 9551 C CA . ASN B 1 451 ? 74.642 72.608 109.394 1.00 34.27 ? 487 ASN B CA 1 ATOM 9552 C C . ASN B 1 451 ? 75.064 71.640 108.293 1.00 39.62 ? 487 ASN B C 1 ATOM 9553 O O . ASN B 1 451 ? 76.131 71.037 108.367 1.00 38.36 ? 487 ASN B O 1 ATOM 9554 C CB . ASN B 1 451 ? 75.008 72.026 110.757 1.00 42.36 ? 487 ASN B CB 1 ATOM 9555 C CG . ASN B 1 451 ? 74.990 73.072 111.858 1.00 49.13 ? 487 ASN B CG 1 ATOM 9556 O OD1 . ASN B 1 451 ? 74.176 73.004 112.787 1.00 48.20 ? 487 ASN B OD1 1 ATOM 9557 N ND2 . ASN B 1 451 ? 75.887 74.050 111.756 1.00 45.25 ? 487 ASN B ND2 1 ATOM 9558 N N . ASP B 1 452 ? 74.229 71.494 107.267 1.00 37.38 ? 488 ASP B N 1 ATOM 9559 C CA . ASP B 1 452 ? 74.553 70.610 106.154 1.00 33.16 ? 488 ASP B CA 1 ATOM 9560 C C . ASP B 1 452 ? 74.894 69.206 106.642 1.00 36.04 ? 488 ASP B C 1 ATOM 9561 O O . ASP B 1 452 ? 75.914 68.642 106.255 1.00 41.45 ? 488 ASP B O 1 ATOM 9562 C CB . ASP B 1 452 ? 75.723 71.180 105.363 1.00 36.00 ? 488 ASP B CB 1 ATOM 9563 C CG . ASP B 1 452 ? 75.382 72.505 104.711 1.00 38.67 ? 488 ASP B CG 1 ATOM 9564 O OD1 . ASP B 1 452 ? 74.299 72.590 104.081 1.00 35.77 ? 488 ASP B OD1 1 ATOM 9565 O OD2 . ASP B 1 452 ? 76.181 73.461 104.845 1.00 41.27 ? 488 ASP B OD2 1 ATOM 9566 N N . LYS B 1 453 ? 74.038 68.659 107.499 1.00 33.18 ? 489 LYS B N 1 ATOM 9567 C CA . LYS B 1 453 ? 74.199 67.296 107.977 1.00 36.13 ? 489 LYS B CA 1 ATOM 9568 C C . LYS B 1 453 ? 73.483 66.336 107.033 1.00 36.46 ? 489 LYS B C 1 ATOM 9569 O O . LYS B 1 453 ? 72.373 66.625 106.560 1.00 33.76 ? 489 LYS B O 1 ATOM 9570 C CB . LYS B 1 453 ? 73.624 67.159 109.387 1.00 40.38 ? 489 LYS B CB 1 ATOM 9571 C CG . LYS B 1 453 ? 73.636 65.727 109.929 1.00 44.13 ? 489 LYS B CG 1 ATOM 9572 C CD . LYS B 1 453 ? 73.061 65.649 111.349 1.00 48.15 ? 489 LYS B CD 1 ATOM 9573 C CE . LYS B 1 453 ? 72.860 64.197 111.799 1.00 50.63 ? 489 LYS B CE 1 ATOM 9574 N N . GLY B 1 454 ? 74.123 65.210 106.741 1.00 33.86 ? 490 GLY B N 1 ATOM 9575 C CA . GLY B 1 454 ? 73.451 64.126 106.037 1.00 31.22 ? 490 GLY B CA 1 ATOM 9576 C C . GLY B 1 454 ? 72.358 63.532 106.906 1.00 36.77 ? 490 GLY B C 1 ATOM 9577 O O . GLY B 1 454 ? 72.627 63.061 108.009 1.00 41.54 ? 490 GLY B O 1 ATOM 9578 N N . LEU B 1 455 ? 71.117 63.563 106.436 1.00 33.90 ? 491 LEU B N 1 ATOM 9579 C CA . LEU B 1 455 ? 70.019 62.973 107.189 1.00 31.17 ? 491 LEU B CA 1 ATOM 9580 C C . LEU B 1 455 ? 69.908 61.466 106.922 1.00 38.19 ? 491 LEU B C 1 ATOM 9581 O O . LEU B 1 455 ? 70.069 60.652 107.842 1.00 37.56 ? 491 LEU B O 1 ATOM 9582 C CB . LEU B 1 455 ? 68.701 63.689 106.883 1.00 33.33 ? 491 LEU B CB 1 ATOM 9583 C CG . LEU B 1 455 ? 68.552 65.130 107.389 1.00 34.16 ? 491 LEU B CG 1 ATOM 9584 C CD1 . LEU B 1 455 ? 67.239 65.724 106.913 1.00 30.97 ? 491 LEU B CD1 1 ATOM 9585 C CD2 . LEU B 1 455 ? 68.611 65.183 108.918 1.00 34.79 ? 491 LEU B CD2 1 ATOM 9586 N N . ARG B 1 456 ? 69.656 61.100 105.665 1.00 39.26 ? 492 ARG B N 1 ATOM 9587 C CA . ARG B 1 456 ? 69.527 59.693 105.268 1.00 31.82 ? 492 ARG B CA 1 ATOM 9588 C C . ARG B 1 456 ? 69.729 59.484 103.763 1.00 38.54 ? 492 ARG B C 1 ATOM 9589 O O . ARG B 1 456 ? 69.683 60.436 102.965 1.00 32.67 ? 492 ARG B O 1 ATOM 9590 C CB . ARG B 1 456 ? 68.163 59.129 105.693 1.00 33.22 ? 492 ARG B CB 1 ATOM 9591 C CG . ARG B 1 456 ? 66.961 59.735 104.977 1.00 32.72 ? 492 ARG B CG 1 ATOM 9592 C CD . ARG B 1 456 ? 65.677 59.503 105.760 1.00 36.13 ? 492 ARG B CD 1 ATOM 9593 N NE . ARG B 1 456 ? 65.727 60.185 107.053 1.00 39.70 ? 492 ARG B NE 1 ATOM 9594 C CZ . ARG B 1 456 ? 65.192 61.380 107.288 1.00 37.65 ? 492 ARG B CZ 1 ATOM 9595 N NH1 . ARG B 1 456 ? 64.542 62.019 106.316 1.00 27.38 ? 492 ARG B NH1 1 ATOM 9596 N NH2 . ARG B 1 456 ? 65.297 61.933 108.498 1.00 33.14 ? 492 ARG B NH2 1 ATOM 9597 N N . VAL B 1 457 ? 69.969 58.229 103.390 1.00 38.36 ? 493 VAL B N 1 ATOM 9598 C CA . VAL B 1 457 ? 70.007 57.818 101.997 1.00 31.23 ? 493 VAL B CA 1 ATOM 9599 C C . VAL B 1 457 ? 68.591 57.472 101.578 1.00 32.66 ? 493 VAL B C 1 ATOM 9600 O O . VAL B 1 457 ? 67.920 56.675 102.228 1.00 32.39 ? 493 VAL B O 1 ATOM 9601 C CB . VAL B 1 457 ? 70.893 56.584 101.800 1.00 36.07 ? 493 VAL B CB 1 ATOM 9602 C CG1 . VAL B 1 457 ? 70.768 56.056 100.374 1.00 31.85 ? 493 VAL B CG1 1 ATOM 9603 C CG2 . VAL B 1 457 ? 72.340 56.915 102.130 1.00 36.12 ? 493 VAL B CG2 1 ATOM 9604 N N . LEU B 1 458 ? 68.132 58.080 100.491 1.00 31.63 ? 494 LEU B N 1 ATOM 9605 C CA . LEU B 1 458 ? 66.770 57.877 100.019 1.00 27.56 ? 494 LEU B CA 1 ATOM 9606 C C . LEU B 1 458 ? 66.692 56.719 99.007 1.00 32.32 ? 494 LEU B C 1 ATOM 9607 O O . LEU B 1 458 ? 65.777 55.894 99.053 1.00 30.50 ? 494 LEU B O 1 ATOM 9608 C CB . LEU B 1 458 ? 66.271 59.169 99.376 1.00 28.72 ? 494 LEU B CB 1 ATOM 9609 C CG . LEU B 1 458 ? 66.250 60.384 100.308 1.00 27.33 ? 494 LEU B CG 1 ATOM 9610 C CD1 . LEU B 1 458 ? 65.965 61.653 99.516 1.00 26.20 ? 494 LEU B CD1 1 ATOM 9611 C CD2 . LEU B 1 458 ? 65.194 60.172 101.386 1.00 26.24 ? 494 LEU B CD2 1 ATOM 9612 N N . GLU B 1 459 ? 67.653 56.678 98.095 1.00 28.55 ? 495 GLU B N 1 ATOM 9613 C CA . GLU B 1 459 ? 67.747 55.600 97.110 1.00 30.80 ? 495 GLU B CA 1 ATOM 9614 C C . GLU B 1 459 ? 69.204 55.451 96.701 1.00 29.49 ? 495 GLU B C 1 ATOM 9615 O O . GLU B 1 459 ? 69.828 56.430 96.304 1.00 30.80 ? 495 GLU B O 1 ATOM 9616 C CB . GLU B 1 459 ? 66.885 55.911 95.876 1.00 31.21 ? 495 GLU B CB 1 ATOM 9617 C CG . GLU B 1 459 ? 67.031 54.900 94.732 1.00 33.63 ? 495 GLU B CG 1 ATOM 9618 C CD . GLU B 1 459 ? 66.585 53.497 95.127 1.00 37.06 ? 495 GLU B CD 1 ATOM 9619 O OE1 . GLU B 1 459 ? 65.413 53.328 95.534 1.00 36.59 ? 495 GLU B OE1 1 ATOM 9620 O OE2 . GLU B 1 459 ? 67.417 52.565 95.045 1.00 40.06 ? 495 GLU B OE2 1 ATOM 9621 N N . ASP B 1 460 ? 69.751 54.236 96.794 1.00 31.49 ? 496 ASP B N 1 ATOM 9622 C CA . ASP B 1 460 ? 71.147 53.994 96.414 1.00 31.72 ? 496 ASP B CA 1 ATOM 9623 C C . ASP B 1 460 ? 71.347 53.032 95.225 1.00 32.31 ? 496 ASP B C 1 ATOM 9624 O O . ASP B 1 460 ? 72.480 52.754 94.821 1.00 32.74 ? 496 ASP B O 1 ATOM 9625 C CB . ASP B 1 460 ? 71.970 53.534 97.627 1.00 32.57 ? 496 ASP B CB 1 ATOM 9626 C CG . ASP B 1 460 ? 71.509 52.183 98.188 1.00 38.87 ? 496 ASP B CG 1 ATOM 9627 O OD1 . ASP B 1 460 ? 70.644 51.507 97.575 1.00 35.69 ? 496 ASP B OD1 1 ATOM 9628 O OD2 . ASP B 1 460 ? 72.035 51.791 99.254 1.00 42.85 ? 496 ASP B OD2 1 ATOM 9629 N N . ASN B 1 461 ? 70.247 52.541 94.660 1.00 33.01 ? 497 ASN B N 1 ATOM 9630 C CA . ASN B 1 461 ? 70.304 51.670 93.490 1.00 32.30 ? 497 ASN B CA 1 ATOM 9631 C C . ASN B 1 461 ? 71.057 50.358 93.738 1.00 37.22 ? 497 ASN B C 1 ATOM 9632 O O . ASN B 1 461 ? 71.673 49.793 92.825 1.00 37.14 ? 497 ASN B O 1 ATOM 9633 C CB . ASN B 1 461 ? 70.881 52.419 92.287 1.00 32.46 ? 497 ASN B CB 1 ATOM 9634 C CG . ASN B 1 461 ? 69.799 53.065 91.443 1.00 35.52 ? 497 ASN B CG 1 ATOM 9635 O OD1 . ASN B 1 461 ? 68.912 52.379 90.940 1.00 31.46 ? 497 ASN B OD1 1 ATOM 9636 N ND2 . ASN B 1 461 ? 69.846 54.391 91.313 1.00 33.67 ? 497 ASN B ND2 1 ATOM 9637 N N . SER B 1 462 ? 70.978 49.864 94.969 1.00 33.67 ? 498 SER B N 1 ATOM 9638 C CA . SER B 1 462 ? 71.643 48.617 95.324 1.00 38.78 ? 498 SER B CA 1 ATOM 9639 C C . SER B 1 462 ? 71.133 47.436 94.486 1.00 35.47 ? 498 SER B C 1 ATOM 9640 O O . SER B 1 462 ? 71.906 46.559 94.124 1.00 38.55 ? 498 SER B O 1 ATOM 9641 C CB . SER B 1 462 ? 71.504 48.332 96.826 1.00 42.06 ? 498 SER B CB 1 ATOM 9642 O OG . SER B 1 462 ? 70.151 48.445 97.250 1.00 45.33 ? 498 SER B OG 1 ATOM 9643 N N . ALA B 1 463 ? 69.843 47.432 94.158 1.00 35.96 ? 499 ALA B N 1 ATOM 9644 C CA . ALA B 1 463 ? 69.270 46.374 93.324 1.00 38.07 ? 499 ALA B CA 1 ATOM 9645 C C . ALA B 1 463 ? 69.926 46.316 91.948 1.00 37.35 ? 499 ALA B C 1 ATOM 9646 O O . ALA B 1 463 ? 70.374 45.256 91.524 1.00 40.13 ? 499 ALA B O 1 ATOM 9647 C CB . ALA B 1 463 ? 67.770 46.539 93.194 1.00 39.21 ? 499 ALA B CB 1 ATOM 9648 N N . LEU B 1 464 ? 69.981 47.452 91.252 1.00 36.63 ? 500 LEU B N 1 ATOM 9649 C CA . LEU B 1 464 ? 70.668 47.528 89.963 1.00 36.81 ? 500 LEU B CA 1 ATOM 9650 C C . LEU B 1 464 ? 72.119 47.124 90.138 1.00 38.62 ? 500 LEU B C 1 ATOM 9651 O O . LEU B 1 464 ? 72.694 46.446 89.285 1.00 37.63 ? 500 LEU B O 1 ATOM 9652 C CB . LEU B 1 464 ? 70.616 48.948 89.385 1.00 35.68 ? 500 LEU B CB 1 ATOM 9653 C CG . LEU B 1 464 ? 70.692 49.181 87.870 1.00 40.93 ? 500 LEU B CG 1 ATOM 9654 C CD1 . LEU B 1 464 ? 71.503 50.439 87.520 1.00 32.11 ? 500 LEU B CD1 1 ATOM 9655 C CD2 . LEU B 1 464 ? 71.200 47.966 87.102 1.00 36.72 ? 500 LEU B CD2 1 ATOM 9656 N N . ASP B 1 465 ? 72.730 47.556 91.234 1.00 33.65 ? 501 ASP B N 1 ATOM 9657 C CA . ASP B 1 465 ? 74.127 47.210 91.450 1.00 37.59 ? 501 ASP B CA 1 ATOM 9658 C C . ASP B 1 465 ? 74.309 45.680 91.495 1.00 39.85 ? 501 ASP B C 1 ATOM 9659 O O . ASP B 1 465 ? 75.232 45.143 90.897 1.00 40.27 ? 501 ASP B O 1 ATOM 9660 C CB . ASP B 1 465 ? 74.661 47.858 92.720 1.00 43.83 ? 501 ASP B CB 1 ATOM 9661 C CG . ASP B 1 465 ? 76.131 47.577 92.935 1.00 49.54 ? 501 ASP B CG 1 ATOM 9662 O OD1 . ASP B 1 465 ? 76.957 48.059 92.127 1.00 48.32 ? 501 ASP B OD1 1 ATOM 9663 O OD2 . ASP B 1 465 ? 76.458 46.868 93.910 1.00 53.44 ? 501 ASP B OD2 1 ATOM 9664 N N . LYS B 1 466 ? 73.418 44.987 92.200 1.00 41.29 ? 502 LYS B N 1 ATOM 9665 C CA . LYS B 1 466 ? 73.493 43.535 92.285 1.00 44.27 ? 502 LYS B CA 1 ATOM 9666 C C . LYS B 1 466 ? 73.335 42.905 90.905 1.00 41.62 ? 502 LYS B C 1 ATOM 9667 O O . LYS B 1 466 ? 74.064 41.983 90.550 1.00 41.57 ? 502 LYS B O 1 ATOM 9668 C CB . LYS B 1 466 ? 72.441 42.985 93.252 1.00 43.29 ? 502 LYS B CB 1 ATOM 9669 C CG . LYS B 1 466 ? 72.796 43.172 94.729 1.00 51.92 ? 502 LYS B CG 1 ATOM 9670 C CD . LYS B 1 466 ? 71.832 42.428 95.660 1.00 56.31 ? 502 LYS B CD 1 ATOM 9671 C CE . LYS B 1 466 ? 70.471 43.123 95.762 1.00 57.99 ? 502 LYS B CE 1 ATOM 9672 N NZ . LYS B 1 466 ? 69.363 42.301 95.174 1.00 63.41 ? 502 LYS B NZ 1 ATOM 9673 N N . MET B 1 467 ? 72.390 43.412 90.120 1.00 41.25 ? 503 MET B N 1 ATOM 9674 C CA . MET B 1 467 ? 72.178 42.882 88.778 1.00 40.47 ? 503 MET B CA 1 ATOM 9675 C C . MET B 1 467 ? 73.412 43.063 87.906 1.00 38.93 ? 503 MET B C 1 ATOM 9676 O O . MET B 1 467 ? 73.822 42.139 87.214 1.00 42.27 ? 503 MET B O 1 ATOM 9677 C CB . MET B 1 467 ? 70.943 43.500 88.123 1.00 41.83 ? 503 MET B CB 1 ATOM 9678 C CG . MET B 1 467 ? 69.634 42.969 88.670 1.00 40.97 ? 503 MET B CG 1 ATOM 9679 S SD . MET B 1 467 ? 68.210 43.575 87.750 1.00 60.46 ? 503 MET B SD 1 ATOM 9680 C CE . MET B 1 467 ? 67.866 45.096 88.656 1.00 56.50 ? 503 MET B CE 1 ATOM 9681 N N . LEU B 1 468 ? 74.029 44.237 87.958 1.00 38.59 ? 504 LEU B N 1 ATOM 9682 C CA . LEU B 1 468 ? 75.159 44.516 87.076 1.00 37.05 ? 504 LEU B CA 1 ATOM 9683 C C . LEU B 1 468 ? 76.411 43.714 87.427 1.00 41.59 ? 504 LEU B C 1 ATOM 9684 O O . LEU B 1 468 ? 77.332 43.623 86.613 1.00 38.11 ? 504 LEU B O 1 ATOM 9685 C CB . LEU B 1 468 ? 75.479 46.016 87.027 1.00 39.78 ? 504 LEU B CB 1 ATOM 9686 C CG . LEU B 1 468 ? 74.379 46.948 86.494 1.00 39.40 ? 504 LEU B CG 1 ATOM 9687 C CD1 . LEU B 1 468 ? 74.887 48.375 86.419 1.00 36.63 ? 504 LEU B CD1 1 ATOM 9688 C CD2 . LEU B 1 468 ? 73.871 46.497 85.140 1.00 35.96 ? 504 LEU B CD2 1 ATOM 9689 N N . GLN B 1 469 ? 76.450 43.139 88.633 1.00 44.68 ? 505 GLN B N 1 ATOM 9690 C CA . GLN B 1 469 ? 77.587 42.305 89.029 1.00 44.49 ? 505 GLN B CA 1 ATOM 9691 C C . GLN B 1 469 ? 77.727 41.133 88.062 1.00 42.76 ? 505 GLN B C 1 ATOM 9692 O O . GLN B 1 469 ? 78.828 40.636 87.834 1.00 46.20 ? 505 GLN B O 1 ATOM 9693 C CB . GLN B 1 469 ? 77.437 41.784 90.468 1.00 48.47 ? 505 GLN B CB 1 ATOM 9694 C CG . GLN B 1 469 ? 77.371 42.857 91.566 1.00 51.90 ? 505 GLN B CG 1 ATOM 9695 C CD . GLN B 1 469 ? 78.697 43.595 91.798 1.00 61.93 ? 505 GLN B CD 1 ATOM 9696 O OE1 . GLN B 1 469 ? 79.389 43.993 90.848 1.00 58.46 ? 505 GLN B OE1 1 ATOM 9697 N NE2 . GLN B 1 469 ? 79.048 43.786 93.073 1.00 62.65 ? 505 GLN B NE2 1 ATOM 9698 N N . ASN B 1 470 ? 76.604 40.720 87.480 1.00 41.98 ? 506 ASN B N 1 ATOM 9699 C CA . ASN B 1 470 ? 76.560 39.583 86.555 1.00 43.52 ? 506 ASN B CA 1 ATOM 9700 C C . ASN B 1 470 ? 76.798 39.949 85.078 1.00 45.65 ? 506 ASN B C 1 ATOM 9701 O O . ASN B 1 470 ? 76.658 39.102 84.186 1.00 47.12 ? 506 ASN B O 1 ATOM 9702 C CB . ASN B 1 470 ? 75.223 38.845 86.712 1.00 45.56 ? 506 ASN B CB 1 ATOM 9703 C CG . ASN B 1 470 ? 74.965 38.397 88.158 1.00 56.09 ? 506 ASN B CG 1 ATOM 9704 O OD1 . ASN B 1 470 ? 75.889 37.975 88.861 1.00 57.24 ? 506 ASN B OD1 1 ATOM 9705 N ND2 . ASN B 1 470 ? 73.707 38.492 88.604 1.00 53.20 ? 506 ASN B ND2 1 ATOM 9706 N N . VAL B 1 471 ? 77.172 41.204 84.826 1.00 46.44 ? 507 VAL B N 1 ATOM 9707 C CA . VAL B 1 471 ? 77.321 41.713 83.459 1.00 40.55 ? 507 VAL B CA 1 ATOM 9708 C C . VAL B 1 471 ? 78.701 42.300 83.196 1.00 39.10 ? 507 VAL B C 1 ATOM 9709 O O . VAL B 1 471 ? 79.280 42.966 84.051 1.00 40.15 ? 507 VAL B O 1 ATOM 9710 C CB . VAL B 1 471 ? 76.260 42.793 83.130 1.00 38.94 ? 507 VAL B CB 1 ATOM 9711 C CG1 . VAL B 1 471 ? 76.369 43.218 81.674 1.00 39.37 ? 507 VAL B CG1 1 ATOM 9712 C CG2 . VAL B 1 471 ? 74.865 42.278 83.423 1.00 38.26 ? 507 VAL B CG2 1 ATOM 9713 N N . GLN B 1 472 ? 79.224 42.047 82.000 1.00 39.47 ? 508 GLN B N 1 ATOM 9714 C CA . GLN B 1 472 ? 80.465 42.666 81.563 1.00 38.37 ? 508 GLN B CA 1 ATOM 9715 C C . GLN B 1 472 ? 80.189 44.092 81.093 1.00 41.14 ? 508 GLN B C 1 ATOM 9716 O O . GLN B 1 472 ? 80.011 44.330 79.901 1.00 37.92 ? 508 GLN B O 1 ATOM 9717 C CB . GLN B 1 472 ? 81.081 41.884 80.406 1.00 41.96 ? 508 GLN B CB 1 ATOM 9718 C CG . GLN B 1 472 ? 81.465 40.457 80.712 1.00 44.54 ? 508 GLN B CG 1 ATOM 9719 C CD . GLN B 1 472 ? 82.137 39.795 79.531 1.00 45.03 ? 508 GLN B CD 1 ATOM 9720 O OE1 . GLN B 1 472 ? 83.155 40.276 79.025 1.00 46.38 ? 508 GLN B OE1 1 ATOM 9721 N NE2 . GLN B 1 472 ? 81.562 38.694 79.069 1.00 44.40 ? 508 GLN B NE2 1 ATOM 9722 N N . MET B 1 473 ? 80.152 45.042 82.023 1.00 37.97 ? 509 MET B N 1 ATOM 9723 C CA . MET B 1 473 ? 79.858 46.428 81.664 1.00 33.43 ? 509 MET B CA 1 ATOM 9724 C C . MET B 1 473 ? 81.089 47.111 81.078 1.00 33.99 ? 509 MET B C 1 ATOM 9725 O O . MET B 1 473 ? 82.214 46.780 81.453 1.00 40.76 ? 509 MET B O 1 ATOM 9726 C CB . MET B 1 473 ? 79.357 47.187 82.893 1.00 32.47 ? 509 MET B CB 1 ATOM 9727 C CG . MET B 1 473 ? 78.010 46.698 83.380 1.00 39.70 ? 509 MET B CG 1 ATOM 9728 S SD . MET B 1 473 ? 76.728 46.975 82.133 1.00 47.09 ? 509 MET B SD 1 ATOM 9729 C CE . MET B 1 473 ? 76.855 48.745 81.931 1.00 39.37 ? 509 MET B CE 1 ATOM 9730 N N . PRO B 1 474 ? 80.887 48.056 80.139 1.00 32.82 ? 510 PRO B N 1 ATOM 9731 C CA . PRO B 1 474 ? 82.021 48.819 79.606 1.00 33.54 ? 510 PRO B CA 1 ATOM 9732 C C . PRO B 1 474 ? 82.444 49.877 80.627 1.00 34.40 ? 510 PRO B C 1 ATOM 9733 O O . PRO B 1 474 ? 81.749 50.029 81.627 1.00 33.12 ? 510 PRO B O 1 ATOM 9734 C CB . PRO B 1 474 ? 81.429 49.504 78.368 1.00 31.82 ? 510 PRO B CB 1 ATOM 9735 C CG . PRO B 1 474 ? 79.999 49.676 78.691 1.00 29.26 ? 510 PRO B CG 1 ATOM 9736 C CD . PRO B 1 474 ? 79.602 48.519 79.592 1.00 31.81 ? 510 PRO B CD 1 ATOM 9737 N N . SER B 1 475 ? 83.547 50.586 80.384 1.00 34.74 ? 511 SER B N 1 ATOM 9738 C CA . SER B 1 475 ? 83.965 51.672 81.272 1.00 39.63 ? 511 SER B CA 1 ATOM 9739 C C . SER B 1 475 ? 83.981 52.993 80.507 1.00 37.51 ? 511 SER B C 1 ATOM 9740 O O . SER B 1 475 ? 83.962 53.000 79.281 1.00 36.93 ? 511 SER B O 1 ATOM 9741 C CB . SER B 1 475 ? 85.343 51.383 81.877 1.00 36.25 ? 511 SER B CB 1 ATOM 9742 O OG . SER B 1 475 ? 86.310 51.198 80.850 1.00 36.07 ? 511 SER B OG 1 ATOM 9743 N N . LYS B 1 476 ? 84.001 54.107 81.231 1.00 36.84 ? 512 LYS B N 1 ATOM 9744 C CA . LYS B 1 476 ? 84.068 55.427 80.611 1.00 36.98 ? 512 LYS B CA 1 ATOM 9745 C C . LYS B 1 476 ? 85.348 56.157 80.985 1.00 36.88 ? 512 LYS B C 1 ATOM 9746 O O . LYS B 1 476 ? 85.728 56.214 82.153 1.00 38.26 ? 512 LYS B O 1 ATOM 9747 C CB . LYS B 1 476 ? 82.864 56.296 81.001 1.00 40.98 ? 512 LYS B CB 1 ATOM 9748 C CG . LYS B 1 476 ? 82.869 57.666 80.302 1.00 40.04 ? 512 LYS B CG 1 ATOM 9749 C CD . LYS B 1 476 ? 81.994 58.718 80.997 1.00 38.81 ? 512 LYS B CD 1 ATOM 9750 C CE . LYS B 1 476 ? 80.574 58.680 80.482 1.00 32.82 ? 512 LYS B CE 1 ATOM 9751 N NZ . LYS B 1 476 ? 79.738 59.818 80.954 1.00 29.74 ? 512 LYS B NZ 1 ATOM 9752 N N . LYS B 1 477 ? 86.015 56.709 79.984 1.00 35.22 ? 513 LYS B N 1 ATOM 9753 C CA . LYS B 1 477 ? 87.148 57.592 80.204 1.00 34.92 ? 513 LYS B CA 1 ATOM 9754 C C . LYS B 1 477 ? 86.726 59.005 79.840 1.00 35.92 ? 513 LYS B C 1 ATOM 9755 O O . LYS B 1 477 ? 86.198 59.226 78.754 1.00 33.84 ? 513 LYS B O 1 ATOM 9756 C CB . LYS B 1 477 ? 88.323 57.181 79.306 1.00 39.89 ? 513 LYS B CB 1 ATOM 9757 C CG . LYS B 1 477 ? 89.586 57.992 79.540 1.00 44.21 ? 513 LYS B CG 1 ATOM 9758 C CD . LYS B 1 477 ? 90.756 57.502 78.695 1.00 52.26 ? 513 LYS B CD 1 ATOM 9759 C CE . LYS B 1 477 ? 92.064 58.144 79.163 1.00 56.01 ? 513 LYS B CE 1 ATOM 9760 N NZ . LYS B 1 477 ? 93.184 57.900 78.206 1.00 62.61 ? 513 LYS B NZ 1 ATOM 9761 N N . LEU B 1 478 ? 86.957 59.950 80.746 1.00 32.57 ? 514 LEU B N 1 ATOM 9762 C CA . LEU B 1 478 ? 86.745 61.376 80.495 1.00 34.51 ? 514 LEU B CA 1 ATOM 9763 C C . LEU B 1 478 ? 88.101 62.061 80.607 1.00 36.98 ? 514 LEU B C 1 ATOM 9764 O O . LEU B 1 478 ? 88.783 61.923 81.617 1.00 39.67 ? 514 LEU B O 1 ATOM 9765 C CB . LEU B 1 478 ? 85.771 61.953 81.529 1.00 33.16 ? 514 LEU B CB 1 ATOM 9766 C CG . LEU B 1 478 ? 85.411 63.441 81.484 1.00 36.78 ? 514 LEU B CG 1 ATOM 9767 C CD1 . LEU B 1 478 ? 84.583 63.807 80.247 1.00 30.24 ? 514 LEU B CD1 1 ATOM 9768 C CD2 . LEU B 1 478 ? 84.675 63.845 82.763 1.00 31.54 ? 514 LEU B CD2 1 ATOM 9769 N N . ASP B 1 479 ? 88.509 62.770 79.566 1.00 35.00 ? 515 ASP B N 1 ATOM 9770 C CA . ASP B 1 479 ? 89.846 63.352 79.521 1.00 40.27 ? 515 ASP B CA 1 ATOM 9771 C C . ASP B 1 479 ? 89.814 64.493 78.519 1.00 35.35 ? 515 ASP B C 1 ATOM 9772 O O . ASP B 1 479 ? 88.749 64.838 78.025 1.00 34.48 ? 515 ASP B O 1 ATOM 9773 C CB . ASP B 1 479 ? 90.874 62.298 79.086 1.00 46.74 ? 515 ASP B CB 1 ATOM 9774 C CG . ASP B 1 479 ? 92.296 62.611 79.571 1.00 50.93 ? 515 ASP B CG 1 ATOM 9775 O OD1 . ASP B 1 479 ? 92.536 63.730 80.080 1.00 45.98 ? 515 ASP B OD1 1 ATOM 9776 O OD2 . ASP B 1 479 ? 93.174 61.727 79.433 1.00 58.83 ? 515 ASP B OD2 1 ATOM 9777 N N . PHE B 1 480 ? 90.963 65.077 78.206 1.00 36.71 ? 516 PHE B N 1 ATOM 9778 C CA . PHE B 1 480 ? 90.990 66.152 77.210 1.00 38.06 ? 516 PHE B CA 1 ATOM 9779 C C . PHE B 1 480 ? 92.141 66.019 76.224 1.00 39.89 ? 516 PHE B C 1 ATOM 9780 O O . PHE B 1 480 ? 93.150 65.377 76.516 1.00 42.00 ? 516 PHE B O 1 ATOM 9781 C CB . PHE B 1 480 ? 91.020 67.528 77.890 1.00 36.67 ? 516 PHE B CB 1 ATOM 9782 C CG . PHE B 1 480 ? 92.215 67.741 78.777 1.00 38.33 ? 516 PHE B CG 1 ATOM 9783 C CD1 . PHE B 1 480 ? 93.395 68.246 78.261 1.00 43.23 ? 516 PHE B CD1 1 ATOM 9784 C CD2 . PHE B 1 480 ? 92.159 67.432 80.127 1.00 43.01 ? 516 PHE B CD2 1 ATOM 9785 C CE1 . PHE B 1 480 ? 94.508 68.439 79.080 1.00 46.31 ? 516 PHE B CE1 1 ATOM 9786 C CE2 . PHE B 1 480 ? 93.266 67.621 80.954 1.00 46.58 ? 516 PHE B CE2 1 ATOM 9787 C CZ . PHE B 1 480 ? 94.438 68.129 80.427 1.00 48.26 ? 516 PHE B CZ 1 ATOM 9788 N N . ILE B 1 481 ? 91.966 66.610 75.044 1.00 40.95 ? 517 ILE B N 1 ATOM 9789 C CA . ILE B 1 481 ? 93.048 66.787 74.090 1.00 38.34 ? 517 ILE B CA 1 ATOM 9790 C C . ILE B 1 481 ? 93.333 68.272 73.977 1.00 43.93 ? 517 ILE B C 1 ATOM 9791 O O . ILE B 1 481 ? 92.621 69.095 74.556 1.00 39.38 ? 517 ILE B O 1 ATOM 9792 C CB . ILE B 1 481 ? 92.713 66.239 72.674 1.00 43.59 ? 517 ILE B CB 1 ATOM 9793 C CG1 . ILE B 1 481 ? 91.429 66.864 72.135 1.00 42.41 ? 517 ILE B CG1 1 ATOM 9794 C CG2 . ILE B 1 481 ? 92.612 64.723 72.684 1.00 48.71 ? 517 ILE B CG2 1 ATOM 9795 C CD1 . ILE B 1 481 ? 91.044 66.359 70.743 1.00 42.54 ? 517 ILE B CD1 1 ATOM 9796 N N . ILE B 1 482 ? 94.381 68.608 73.231 1.00 48.74 ? 518 ILE B N 1 ATOM 9797 C CA . ILE B 1 482 ? 94.762 69.999 73.029 1.00 47.22 ? 518 ILE B CA 1 ATOM 9798 C C . ILE B 1 482 ? 94.720 70.338 71.548 1.00 47.11 ? 518 ILE B C 1 ATOM 9799 O O . ILE B 1 482 ? 95.492 69.805 70.751 1.00 53.59 ? 518 ILE B O 1 ATOM 9800 C CB . ILE B 1 482 ? 96.179 70.293 73.569 1.00 46.40 ? 518 ILE B CB 1 ATOM 9801 C CG1 . ILE B 1 482 ? 96.325 69.785 75.000 1.00 43.02 ? 518 ILE B CG1 1 ATOM 9802 C CG2 . ILE B 1 482 ? 96.466 71.785 73.529 1.00 46.28 ? 518 ILE B CG2 1 ATOM 9803 C CD1 . ILE B 1 482 ? 95.625 70.654 75.997 1.00 45.33 ? 518 ILE B CD1 1 ATOM 9804 N N . LEU B 1 483 ? 93.795 71.212 71.183 1.00 45.71 ? 519 LEU B N 1 ATOM 9805 C CA . LEU B 1 483 ? 93.757 71.777 69.845 1.00 47.46 ? 519 LEU B CA 1 ATOM 9806 C C . LEU B 1 483 ? 94.128 73.238 70.008 1.00 49.69 ? 519 LEU B C 1 ATOM 9807 O O . LEU B 1 483 ? 93.484 73.950 70.769 1.00 45.71 ? 519 LEU B O 1 ATOM 9808 C CB . LEU B 1 483 ? 92.354 71.648 69.239 1.00 45.02 ? 519 LEU B CB 1 ATOM 9809 C CG . LEU B 1 483 ? 91.975 70.370 68.481 1.00 47.50 ? 519 LEU B CG 1 ATOM 9810 C CD1 . LEU B 1 483 ? 92.823 69.171 68.878 1.00 50.57 ? 519 LEU B CD1 1 ATOM 9811 C CD2 . LEU B 1 483 ? 90.495 70.062 68.639 1.00 42.23 ? 519 LEU B CD2 1 ATOM 9812 N N . ASN B 1 484 ? 95.179 73.676 69.320 1.00 52.90 ? 520 ASN B N 1 ATOM 9813 C CA . ASN B 1 484 ? 95.598 75.075 69.364 1.00 53.23 ? 520 ASN B CA 1 ATOM 9814 C C . ASN B 1 484 ? 95.726 75.640 70.755 1.00 51.13 ? 520 ASN B C 1 ATOM 9815 O O . ASN B 1 484 ? 95.116 76.663 71.062 1.00 55.22 ? 520 ASN B O 1 ATOM 9816 C CB . ASN B 1 484 ? 94.613 75.953 68.610 1.00 55.55 ? 520 ASN B CB 1 ATOM 9817 C CG . ASN B 1 484 ? 94.805 75.883 67.141 1.00 61.14 ? 520 ASN B CG 1 ATOM 9818 O OD1 . ASN B 1 484 ? 95.465 74.975 66.632 1.00 61.50 ? 520 ASN B OD1 1 ATOM 9819 N ND2 . ASN B 1 484 ? 94.222 76.833 66.431 1.00 64.82 ? 520 ASN B ND2 1 ATOM 9820 N N . GLU B 1 485 ? 96.501 74.976 71.599 1.00 49.35 ? 521 GLU B N 1 ATOM 9821 C CA . GLU B 1 485 ? 96.781 75.496 72.934 1.00 51.12 ? 521 GLU B CA 1 ATOM 9822 C C . GLU B 1 485 ? 95.574 75.572 73.881 1.00 49.46 ? 521 GLU B C 1 ATOM 9823 O O . GLU B 1 485 ? 95.691 76.109 74.984 1.00 53.80 ? 521 GLU B O 1 ATOM 9824 C CB . GLU B 1 485 ? 97.454 76.867 72.830 1.00 52.18 ? 521 GLU B CB 1 ATOM 9825 C CG . GLU B 1 485 ? 98.751 76.842 72.038 1.00 56.66 ? 521 GLU B CG 1 ATOM 9826 C CD . GLU B 1 485 ? 99.514 78.152 72.118 1.00 65.62 ? 521 GLU B CD 1 ATOM 9827 O OE1 . GLU B 1 485 ? 99.186 78.985 73.001 1.00 66.56 ? 521 GLU B OE1 1 ATOM 9828 O OE2 . GLU B 1 485 ? 100.439 78.344 71.294 1.00 65.28 ? 521 GLU B OE2 1 ATOM 9829 N N . THR B 1 486 ? 94.426 75.038 73.465 1.00 45.13 ? 522 THR B N 1 ATOM 9830 C CA . THR B 1 486 ? 93.246 75.016 74.334 1.00 43.09 ? 522 THR B CA 1 ATOM 9831 C C . THR B 1 486 ? 92.846 73.585 74.671 1.00 43.05 ? 522 THR B C 1 ATOM 9832 O O . THR B 1 486 ? 93.028 72.681 73.852 1.00 43.53 ? 522 THR B O 1 ATOM 9833 C CB . THR B 1 486 ? 92.040 75.728 73.690 1.00 45.29 ? 522 THR B CB 1 ATOM 9834 O OG1 . THR B 1 486 ? 92.311 77.132 73.586 1.00 48.08 ? 522 THR B OG1 1 ATOM 9835 C CG2 . THR B 1 486 ? 90.783 75.521 74.533 1.00 41.85 ? 522 THR B CG2 1 ATOM 9836 N N . LYS B 1 487 ? 92.305 73.378 75.871 1.00 36.84 ? 523 LYS B N 1 ATOM 9837 C CA . LYS B 1 487 ? 91.802 72.064 76.264 1.00 36.45 ? 523 LYS B CA 1 ATOM 9838 C C . LYS B 1 487 ? 90.404 71.839 75.699 1.00 35.17 ? 523 LYS B C 1 ATOM 9839 O O . LYS B 1 487 ? 89.547 72.720 75.773 1.00 33.14 ? 523 LYS B O 1 ATOM 9840 C CB . LYS B 1 487 ? 91.738 71.931 77.789 1.00 38.59 ? 523 LYS B CB 1 ATOM 9841 C CG . LYS B 1 487 ? 93.069 71.723 78.488 1.00 46.64 ? 523 LYS B CG 1 ATOM 9842 C CD . LYS B 1 487 ? 92.863 71.531 79.998 1.00 47.39 ? 523 LYS B CD 1 ATOM 9843 C CE . LYS B 1 487 ? 94.194 71.459 80.735 1.00 55.53 ? 523 LYS B CE 1 ATOM 9844 N NZ . LYS B 1 487 ? 94.060 71.855 82.168 1.00 59.03 ? 523 LYS B NZ 1 ATOM 9845 N N . PHE B 1 488 ? 90.180 70.662 75.126 1.00 30.08 ? 524 PHE B N 1 ATOM 9846 C CA . PHE B 1 488 ? 88.844 70.251 74.712 1.00 27.72 ? 524 PHE B CA 1 ATOM 9847 C C . PHE B 1 488 ? 88.583 68.849 75.222 1.00 29.54 ? 524 PHE B C 1 ATOM 9848 O O . PHE B 1 488 ? 89.407 67.955 75.066 1.00 30.78 ? 524 PHE B O 1 ATOM 9849 C CB . PHE B 1 488 ? 88.699 70.307 73.194 1.00 31.23 ? 524 PHE B CB 1 ATOM 9850 C CG . PHE B 1 488 ? 88.722 71.710 72.635 1.00 31.89 ? 524 PHE B CG 1 ATOM 9851 C CD1 . PHE B 1 488 ? 87.601 72.514 72.699 1.00 31.27 ? 524 PHE B CD1 1 ATOM 9852 C CD2 . PHE B 1 488 ? 89.859 72.218 72.050 1.00 36.50 ? 524 PHE B CD2 1 ATOM 9853 C CE1 . PHE B 1 488 ? 87.617 73.798 72.188 1.00 32.89 ? 524 PHE B CE1 1 ATOM 9854 C CE2 . PHE B 1 488 ? 89.877 73.504 71.532 1.00 37.77 ? 524 PHE B CE2 1 ATOM 9855 C CZ . PHE B 1 488 ? 88.757 74.293 71.605 1.00 32.23 ? 524 PHE B CZ 1 ATOM 9856 N N . TRP B 1 489 ? 87.426 68.654 75.827 1.00 25.92 ? 525 TRP B N 1 ATOM 9857 C CA . TRP B 1 489 ? 87.139 67.410 76.526 1.00 29.75 ? 525 TRP B CA 1 ATOM 9858 C C . TRP B 1 489 ? 86.458 66.372 75.653 1.00 28.81 ? 525 TRP B C 1 ATOM 9859 O O . TRP B 1 489 ? 85.715 66.700 74.744 1.00 29.62 ? 525 TRP B O 1 ATOM 9860 C CB . TRP B 1 489 ? 86.287 67.708 77.755 1.00 29.52 ? 525 TRP B CB 1 ATOM 9861 C CG . TRP B 1 489 ? 87.068 68.472 78.794 1.00 34.01 ? 525 TRP B CG 1 ATOM 9862 C CD1 . TRP B 1 489 ? 87.371 69.806 78.780 1.00 32.71 ? 525 TRP B CD1 1 ATOM 9863 C CD2 . TRP B 1 489 ? 87.662 67.938 79.982 1.00 31.60 ? 525 TRP B CD2 1 ATOM 9864 N NE1 . TRP B 1 489 ? 88.109 70.135 79.895 1.00 29.76 ? 525 TRP B NE1 1 ATOM 9865 C CE2 . TRP B 1 489 ? 88.304 69.005 80.645 1.00 34.21 ? 525 TRP B CE2 1 ATOM 9866 C CE3 . TRP B 1 489 ? 87.718 66.661 80.547 1.00 30.54 ? 525 TRP B CE3 1 ATOM 9867 C CZ2 . TRP B 1 489 ? 88.990 68.830 81.843 1.00 34.66 ? 525 TRP B CZ2 1 ATOM 9868 C CZ3 . TRP B 1 489 ? 88.394 66.492 81.737 1.00 35.75 ? 525 TRP B CZ3 1 ATOM 9869 C CH2 . TRP B 1 489 ? 89.019 67.571 82.376 1.00 33.35 ? 525 TRP B CH2 1 ATOM 9870 N N . TYR B 1 490 ? 86.720 65.110 75.937 1.00 26.34 ? 526 TYR B N 1 ATOM 9871 C CA . TYR B 1 490 ? 86.045 64.038 75.230 1.00 30.23 ? 526 TYR B CA 1 ATOM 9872 C C . TYR B 1 490 ? 85.749 62.929 76.211 1.00 31.89 ? 526 TYR B C 1 ATOM 9873 O O . TYR B 1 490 ? 86.300 62.892 77.313 1.00 33.45 ? 526 TYR B O 1 ATOM 9874 C CB . TYR B 1 490 ? 86.916 63.528 74.070 1.00 33.21 ? 526 TYR B CB 1 ATOM 9875 C CG . TYR B 1 490 ? 88.162 62.782 74.500 1.00 32.51 ? 526 TYR B CG 1 ATOM 9876 C CD1 . TYR B 1 490 ? 88.156 61.401 74.609 1.00 35.72 ? 526 TYR B CD1 1 ATOM 9877 C CD2 . TYR B 1 490 ? 89.339 63.460 74.810 1.00 37.17 ? 526 TYR B CD2 1 ATOM 9878 C CE1 . TYR B 1 490 ? 89.278 60.706 75.003 1.00 36.68 ? 526 TYR B CE1 1 ATOM 9879 C CE2 . TYR B 1 490 ? 90.473 62.777 75.206 1.00 37.00 ? 526 TYR B CE2 1 ATOM 9880 C CZ . TYR B 1 490 ? 90.434 61.394 75.300 1.00 46.61 ? 526 TYR B CZ 1 ATOM 9881 O OH . TYR B 1 490 ? 91.549 60.685 75.691 1.00 53.37 ? 526 TYR B OH 1 ATOM 9882 N N . GLN B 1 491 ? 84.863 62.027 75.837 1.00 30.24 ? 527 GLN B N 1 ATOM 9883 C CA . GLN B 1 491 ? 84.674 60.825 76.627 1.00 27.35 ? 527 GLN B CA 1 ATOM 9884 C C . GLN B 1 491 ? 84.718 59.618 75.704 1.00 33.08 ? 527 GLN B C 1 ATOM 9885 O O . GLN B 1 491 ? 84.406 59.723 74.508 1.00 27.67 ? 527 GLN B O 1 ATOM 9886 C CB . GLN B 1 491 ? 83.351 60.867 77.388 1.00 29.85 ? 527 GLN B CB 1 ATOM 9887 C CG . GLN B 1 491 ? 82.095 60.917 76.528 1.00 28.66 ? 527 GLN B CG 1 ATOM 9888 C CD . GLN B 1 491 ? 80.829 60.744 77.367 1.00 34.21 ? 527 GLN B CD 1 ATOM 9889 O OE1 . GLN B 1 491 ? 80.659 61.393 78.399 1.00 33.80 ? 527 GLN B OE1 1 ATOM 9890 N NE2 . GLN B 1 491 ? 79.953 59.844 76.941 1.00 34.24 ? 527 GLN B NE2 1 ATOM 9891 N N . MET B 1 492 ? 85.111 58.475 76.254 1.00 31.55 ? 528 MET B N 1 ATOM 9892 C CA . MET B 1 492 ? 85.062 57.220 75.507 1.00 31.13 ? 528 MET B CA 1 ATOM 9893 C C . MET B 1 492 ? 84.425 56.121 76.336 1.00 32.33 ? 528 MET B C 1 ATOM 9894 O O . MET B 1 492 ? 84.850 55.856 77.462 1.00 33.61 ? 528 MET B O 1 ATOM 9895 C CB . MET B 1 492 ? 86.464 56.772 75.102 1.00 31.34 ? 528 MET B CB 1 ATOM 9896 C CG . MET B 1 492 ? 87.122 57.638 74.069 1.00 34.32 ? 528 MET B CG 1 ATOM 9897 S SD . MET B 1 492 ? 88.734 56.991 73.578 1.00 36.39 ? 528 MET B SD 1 ATOM 9898 C CE . MET B 1 492 ? 89.074 58.059 72.177 1.00 39.24 ? 528 MET B CE 1 ATOM 9899 N N . ILE B 1 493 ? 83.398 55.490 75.780 1.00 28.97 ? 529 ILE B N 1 ATOM 9900 C CA . ILE B 1 493 ? 82.887 54.250 76.334 1.00 28.91 ? 529 ILE B CA 1 ATOM 9901 C C . ILE B 1 493 ? 83.817 53.157 75.821 1.00 31.62 ? 529 ILE B C 1 ATOM 9902 O O . ILE B 1 493 ? 83.888 52.924 74.620 1.00 30.46 ? 529 ILE B O 1 ATOM 9903 C CB . ILE B 1 493 ? 81.462 53.960 75.840 1.00 30.73 ? 529 ILE B CB 1 ATOM 9904 C CG1 . ILE B 1 493 ? 80.597 55.205 75.951 1.00 31.75 ? 529 ILE B CG1 1 ATOM 9905 C CG2 . ILE B 1 493 ? 80.847 52.832 76.625 1.00 32.73 ? 529 ILE B CG2 1 ATOM 9906 C CD1 . ILE B 1 493 ? 80.487 55.691 77.356 1.00 31.34 ? 529 ILE B CD1 1 ATOM 9907 N N . LEU B 1 494 ? 84.531 52.496 76.724 1.00 29.76 ? 530 LEU B N 1 ATOM 9908 C CA . LEU B 1 494 ? 85.498 51.472 76.346 1.00 33.62 ? 530 LEU B CA 1 ATOM 9909 C C . LEU B 1 494 ? 84.942 50.086 76.640 1.00 33.87 ? 530 LEU B C 1 ATOM 9910 O O . LEU B 1 494 ? 84.298 49.875 77.666 1.00 33.70 ? 530 LEU B O 1 ATOM 9911 C CB . LEU B 1 494 ? 86.821 51.673 77.096 1.00 32.59 ? 530 LEU B CB 1 ATOM 9912 C CG . LEU B 1 494 ? 87.517 53.025 76.904 1.00 33.18 ? 530 LEU B CG 1 ATOM 9913 C CD1 . LEU B 1 494 ? 88.563 53.292 77.994 1.00 37.12 ? 530 LEU B CD1 1 ATOM 9914 C CD2 . LEU B 1 494 ? 88.136 53.128 75.522 1.00 32.32 ? 530 LEU B CD2 1 ATOM 9915 N N . PRO B 1 495 ? 85.168 49.134 75.724 1.00 32.23 ? 531 PRO B N 1 ATOM 9916 C CA . PRO B 1 495 ? 84.660 47.774 75.925 1.00 33.81 ? 531 PRO B CA 1 ATOM 9917 C C . PRO B 1 495 ? 85.218 47.149 77.204 1.00 36.24 ? 531 PRO B C 1 ATOM 9918 O O . PRO B 1 495 ? 86.301 47.508 77.652 1.00 36.53 ? 531 PRO B O 1 ATOM 9919 C CB . PRO B 1 495 ? 85.197 47.027 74.705 1.00 33.88 ? 531 PRO B CB 1 ATOM 9920 C CG . PRO B 1 495 ? 85.328 48.086 73.640 1.00 33.23 ? 531 PRO B CG 1 ATOM 9921 C CD . PRO B 1 495 ? 85.699 49.349 74.364 1.00 31.28 ? 531 PRO B CD 1 ATOM 9922 N N . PRO B 1 496 ? 84.482 46.213 77.800 1.00 37.77 ? 532 PRO B N 1 ATOM 9923 C CA . PRO B 1 496 ? 85.052 45.558 78.980 1.00 40.40 ? 532 PRO B CA 1 ATOM 9924 C C . PRO B 1 496 ? 86.388 44.885 78.635 1.00 43.55 ? 532 PRO B C 1 ATOM 9925 O O . PRO B 1 496 ? 86.586 44.442 77.494 1.00 44.44 ? 532 PRO B O 1 ATOM 9926 C CB . PRO B 1 496 ? 83.985 44.527 79.354 1.00 42.04 ? 532 PRO B CB 1 ATOM 9927 C CG . PRO B 1 496 ? 83.192 44.324 78.119 1.00 38.83 ? 532 PRO B CG 1 ATOM 9928 C CD . PRO B 1 496 ? 83.185 45.641 77.413 1.00 37.62 ? 532 PRO B CD 1 ATOM 9929 N N . HIS B 1 497 ? 87.301 44.834 79.601 1.00 44.37 ? 533 HIS B N 1 ATOM 9930 C CA . HIS B 1 497 ? 88.618 44.233 79.390 1.00 40.15 ? 533 HIS B CA 1 ATOM 9931 C C . HIS B 1 497 ? 89.404 44.983 78.332 1.00 41.97 ? 533 HIS B C 1 ATOM 9932 O O . HIS B 1 497 ? 90.142 44.382 77.556 1.00 41.78 ? 533 HIS B O 1 ATOM 9933 C CB . HIS B 1 497 ? 88.487 42.764 78.994 1.00 45.09 ? 533 HIS B CB 1 ATOM 9934 C CG . HIS B 1 497 ? 87.703 41.947 79.972 1.00 43.36 ? 533 HIS B CG 1 ATOM 9935 N ND1 . HIS B 1 497 ? 86.539 41.293 79.632 1.00 42.65 ? 533 HIS B ND1 1 ATOM 9936 C CD2 . HIS B 1 497 ? 87.910 41.690 81.285 1.00 46.38 ? 533 HIS B CD2 1 ATOM 9937 C CE1 . HIS B 1 497 ? 86.063 40.664 80.692 1.00 48.96 ? 533 HIS B CE1 1 ATOM 9938 N NE2 . HIS B 1 497 ? 86.878 40.888 81.708 1.00 55.06 ? 533 HIS B NE2 1 ATOM 9939 N N . PHE B 1 498 ? 89.237 46.299 78.302 1.00 41.05 ? 534 PHE B N 1 ATOM 9940 C CA . PHE B 1 498 ? 89.923 47.127 77.324 1.00 41.92 ? 534 PHE B CA 1 ATOM 9941 C C . PHE B 1 498 ? 91.409 46.823 77.368 1.00 46.64 ? 534 PHE B C 1 ATOM 9942 O O . PHE B 1 498 ? 92.019 46.847 78.435 1.00 46.69 ? 534 PHE B O 1 ATOM 9943 C CB . PHE B 1 498 ? 89.673 48.606 77.602 1.00 38.73 ? 534 PHE B CB 1 ATOM 9944 C CG . PHE B 1 498 ? 90.362 49.526 76.645 1.00 42.56 ? 534 PHE B CG 1 ATOM 9945 C CD1 . PHE B 1 498 ? 89.983 49.574 75.311 1.00 42.59 ? 534 PHE B CD1 1 ATOM 9946 C CD2 . PHE B 1 498 ? 91.379 50.365 77.080 1.00 46.30 ? 534 PHE B CD2 1 ATOM 9947 C CE1 . PHE B 1 498 ? 90.613 50.432 74.424 1.00 43.32 ? 534 PHE B CE1 1 ATOM 9948 C CE2 . PHE B 1 498 ? 92.012 51.228 76.197 1.00 46.68 ? 534 PHE B CE2 1 ATOM 9949 C CZ . PHE B 1 498 ? 91.630 51.259 74.869 1.00 45.51 ? 534 PHE B CZ 1 ATOM 9950 N N . ASP B 1 499 ? 91.972 46.506 76.206 1.00 47.30 ? 535 ASP B N 1 ATOM 9951 C CA . ASP B 1 499 ? 93.394 46.199 76.071 1.00 51.54 ? 535 ASP B CA 1 ATOM 9952 C C . ASP B 1 499 ? 94.030 47.227 75.141 1.00 50.32 ? 535 ASP B C 1 ATOM 9953 O O . ASP B 1 499 ? 93.836 47.169 73.929 1.00 51.08 ? 535 ASP B O 1 ATOM 9954 C CB . ASP B 1 499 ? 93.565 44.784 75.501 1.00 54.57 ? 535 ASP B CB 1 ATOM 9955 C CG . ASP B 1 499 ? 95.025 44.337 75.443 1.00 59.18 ? 535 ASP B CG 1 ATOM 9956 O OD1 . ASP B 1 499 ? 95.924 45.203 75.377 1.00 52.93 ? 535 ASP B OD1 1 ATOM 9957 O OD2 . ASP B 1 499 ? 95.272 43.109 75.456 1.00 63.97 ? 535 ASP B OD2 1 ATOM 9958 N N . LYS B 1 500 ? 94.790 48.161 75.707 1.00 48.57 ? 536 LYS B N 1 ATOM 9959 C CA . LYS B 1 500 ? 95.309 49.306 74.954 1.00 49.25 ? 536 LYS B CA 1 ATOM 9960 C C . LYS B 1 500 ? 96.229 48.923 73.804 1.00 52.98 ? 536 LYS B C 1 ATOM 9961 O O . LYS B 1 500 ? 96.609 49.775 72.997 1.00 55.88 ? 536 LYS B O 1 ATOM 9962 C CB . LYS B 1 500 ? 96.038 50.281 75.888 1.00 49.81 ? 536 LYS B CB 1 ATOM 9963 N N . SER B 1 501 ? 96.595 47.647 73.727 1.00 52.89 ? 537 SER B N 1 ATOM 9964 C CA . SER B 1 501 ? 97.473 47.187 72.654 1.00 57.03 ? 537 SER B CA 1 ATOM 9965 C C . SER B 1 501 ? 96.692 46.750 71.418 1.00 56.42 ? 537 SER B C 1 ATOM 9966 O O . SER B 1 501 ? 97.249 46.668 70.322 1.00 59.59 ? 537 SER B O 1 ATOM 9967 C CB . SER B 1 501 ? 98.410 46.066 73.133 1.00 57.26 ? 537 SER B CB 1 ATOM 9968 O OG . SER B 1 501 ? 97.702 44.876 73.438 1.00 57.56 ? 537 SER B OG 1 ATOM 9969 N N . LYS B 1 502 ? 95.403 46.476 71.592 1.00 55.24 ? 538 LYS B N 1 ATOM 9970 C CA . LYS B 1 502 ? 94.561 46.074 70.468 1.00 54.84 ? 538 LYS B CA 1 ATOM 9971 C C . LYS B 1 502 ? 94.058 47.282 69.676 1.00 52.75 ? 538 LYS B C 1 ATOM 9972 O O . LYS B 1 502 ? 94.224 48.424 70.106 1.00 52.68 ? 538 LYS B O 1 ATOM 9973 C CB . LYS B 1 502 ? 93.402 45.195 70.944 1.00 52.76 ? 538 LYS B CB 1 ATOM 9974 C CG . LYS B 1 502 ? 93.871 43.846 71.448 1.00 59.58 ? 538 LYS B CG 1 ATOM 9975 C CD . LYS B 1 502 ? 92.722 42.939 71.846 1.00 68.41 ? 538 LYS B CD 1 ATOM 9976 C CE . LYS B 1 502 ? 93.250 41.688 72.551 1.00 73.12 ? 538 LYS B CE 1 ATOM 9977 N NZ . LYS B 1 502 ? 92.161 40.829 73.104 1.00 76.20 ? 538 LYS B NZ 1 ATOM 9978 N N . LYS B 1 503 ? 93.472 47.023 68.510 1.00 49.20 ? 539 LYS B N 1 ATOM 9979 C CA . LYS B 1 503 ? 92.903 48.075 67.678 1.00 48.90 ? 539 LYS B CA 1 ATOM 9980 C C . LYS B 1 503 ? 91.388 47.882 67.590 1.00 47.68 ? 539 LYS B C 1 ATOM 9981 O O . LYS B 1 503 ? 90.920 46.911 66.999 1.00 49.95 ? 539 LYS B O 1 ATOM 9982 C CB . LYS B 1 503 ? 93.518 48.040 66.273 1.00 49.78 ? 539 LYS B CB 1 ATOM 9983 C CG . LYS B 1 503 ? 95.007 48.378 66.202 1.00 52.48 ? 539 LYS B CG 1 ATOM 9984 C CD . LYS B 1 503 ? 95.236 49.872 66.017 1.00 53.75 ? 539 LYS B CD 1 ATOM 9985 C CE . LYS B 1 503 ? 96.568 50.168 65.333 1.00 58.70 ? 539 LYS B CE 1 ATOM 9986 N NZ . LYS B 1 503 ? 97.735 49.683 66.124 1.00 61.36 ? 539 LYS B NZ 1 ATOM 9987 N N . TYR B 1 504 ? 90.629 48.802 68.183 1.00 41.38 ? 540 TYR B N 1 ATOM 9988 C CA . TYR B 1 504 ? 89.169 48.731 68.180 1.00 35.09 ? 540 TYR B CA 1 ATOM 9989 C C . TYR B 1 504 ? 88.585 49.670 67.129 1.00 35.09 ? 540 TYR B C 1 ATOM 9990 O O . TYR B 1 504 ? 89.158 50.719 66.844 1.00 35.78 ? 540 TYR B O 1 ATOM 9991 C CB . TYR B 1 504 ? 88.616 49.143 69.550 1.00 36.51 ? 540 TYR B CB 1 ATOM 9992 C CG . TYR B 1 504 ? 89.055 48.256 70.694 1.00 35.81 ? 540 TYR B CG 1 ATOM 9993 C CD1 . TYR B 1 504 ? 90.327 48.365 71.235 1.00 38.94 ? 540 TYR B CD1 1 ATOM 9994 C CD2 . TYR B 1 504 ? 88.194 47.318 71.233 1.00 35.69 ? 540 TYR B CD2 1 ATOM 9995 C CE1 . TYR B 1 504 ? 90.733 47.554 72.276 1.00 41.60 ? 540 TYR B CE1 1 ATOM 9996 C CE2 . TYR B 1 504 ? 88.591 46.501 72.274 1.00 39.66 ? 540 TYR B CE2 1 ATOM 9997 C CZ . TYR B 1 504 ? 89.860 46.626 72.791 1.00 41.07 ? 540 TYR B CZ 1 ATOM 9998 O OH . TYR B 1 504 ? 90.246 45.813 73.829 1.00 42.76 ? 540 TYR B OH 1 ATOM 9999 N N . PRO B 1 505 ? 87.426 49.304 66.560 1.00 35.38 ? 541 PRO B N 1 ATOM 10000 C CA . PRO B 1 505 ? 86.669 50.255 65.739 1.00 31.93 ? 541 PRO B CA 1 ATOM 10001 C C . PRO B 1 505 ? 86.159 51.387 66.632 1.00 32.77 ? 541 PRO B C 1 ATOM 10002 O O . PRO B 1 505 ? 85.977 51.150 67.825 1.00 32.71 ? 541 PRO B O 1 ATOM 10003 C CB . PRO B 1 505 ? 85.493 49.416 65.230 1.00 31.13 ? 541 PRO B CB 1 ATOM 10004 C CG . PRO B 1 505 ? 85.315 48.361 66.275 1.00 35.40 ? 541 PRO B CG 1 ATOM 10005 C CD . PRO B 1 505 ? 86.700 48.039 66.769 1.00 34.25 ? 541 PRO B CD 1 ATOM 10006 N N . LEU B 1 506 ? 85.942 52.580 66.077 1.00 33.60 ? 542 LEU B N 1 ATOM 10007 C CA . LEU B 1 506 ? 85.461 53.718 66.865 1.00 30.71 ? 542 LEU B CA 1 ATOM 10008 C C . LEU B 1 506 ? 84.220 54.357 66.242 1.00 32.96 ? 542 LEU B C 1 ATOM 10009 O O . LEU B 1 506 ? 84.218 54.675 65.056 1.00 32.55 ? 542 LEU B O 1 ATOM 10010 C CB . LEU B 1 506 ? 86.548 54.787 66.986 1.00 30.83 ? 542 LEU B CB 1 ATOM 10011 C CG . LEU B 1 506 ? 86.180 56.000 67.863 1.00 32.25 ? 542 LEU B CG 1 ATOM 10012 C CD1 . LEU B 1 506 ? 87.195 56.238 68.971 1.00 33.47 ? 542 LEU B CD1 1 ATOM 10013 C CD2 . LEU B 1 506 ? 86.027 57.241 67.027 1.00 31.84 ? 542 LEU B CD2 1 ATOM 10014 N N . LEU B 1 507 ? 83.172 54.558 67.042 1.00 28.96 ? 543 LEU B N 1 ATOM 10015 C CA . LEU B 1 507 ? 82.006 55.313 66.590 1.00 27.44 ? 543 LEU B CA 1 ATOM 10016 C C . LEU B 1 507 ? 81.995 56.667 67.281 1.00 28.40 ? 543 LEU B C 1 ATOM 10017 O O . LEU B 1 507 ? 81.981 56.730 68.502 1.00 28.91 ? 543 LEU B O 1 ATOM 10018 C CB . LEU B 1 507 ? 80.723 54.558 66.926 1.00 26.12 ? 543 LEU B CB 1 ATOM 10019 C CG . LEU B 1 507 ? 79.388 55.288 66.754 1.00 26.64 ? 543 LEU B CG 1 ATOM 10020 C CD1 . LEU B 1 507 ? 79.157 55.730 65.313 1.00 25.48 ? 543 LEU B CD1 1 ATOM 10021 C CD2 . LEU B 1 507 ? 78.228 54.402 67.232 1.00 27.52 ? 543 LEU B CD2 1 ATOM 10022 N N . LEU B 1 508 ? 82.014 57.749 66.512 1.00 25.05 ? 544 LEU B N 1 ATOM 10023 C CA . LEU B 1 508 ? 81.898 59.082 67.088 1.00 25.81 ? 544 LEU B CA 1 ATOM 10024 C C . LEU B 1 508 ? 80.425 59.471 67.226 1.00 29.68 ? 544 LEU B C 1 ATOM 10025 O O . LEU B 1 508 ? 79.706 59.695 66.238 1.00 27.29 ? 544 LEU B O 1 ATOM 10026 C CB . LEU B 1 508 ? 82.630 60.109 66.231 1.00 28.32 ? 544 LEU B CB 1 ATOM 10027 C CG . LEU B 1 508 ? 82.791 61.504 66.829 1.00 31.61 ? 544 LEU B CG 1 ATOM 10028 C CD1 . LEU B 1 508 ? 83.753 61.459 68.016 1.00 31.45 ? 544 LEU B CD1 1 ATOM 10029 C CD2 . LEU B 1 508 ? 83.285 62.490 65.793 1.00 28.29 ? 544 LEU B CD2 1 ATOM 10030 N N . ASP B 1 509 ? 79.979 59.528 68.467 1.00 27.60 ? 545 ASP B N 1 ATOM 10031 C CA . ASP B 1 509 ? 78.626 59.945 68.804 1.00 28.61 ? 545 ASP B CA 1 ATOM 10032 C C . ASP B 1 509 ? 78.596 61.481 68.937 1.00 32.45 ? 545 ASP B C 1 ATOM 10033 O O . ASP B 1 509 ? 79.207 62.045 69.854 1.00 31.93 ? 545 ASP B O 1 ATOM 10034 C CB . ASP B 1 509 ? 78.230 59.238 70.108 1.00 27.83 ? 545 ASP B CB 1 ATOM 10035 C CG . ASP B 1 509 ? 76.868 59.633 70.606 1.00 32.20 ? 545 ASP B CG 1 ATOM 10036 O OD1 . ASP B 1 509 ? 76.261 60.564 70.023 1.00 33.29 ? 545 ASP B OD1 1 ATOM 10037 O OD2 . ASP B 1 509 ? 76.417 59.025 71.612 1.00 38.09 ? 545 ASP B OD2 1 ATOM 10038 N N . VAL B 1 510 ? 77.917 62.166 68.015 1.00 32.44 ? 546 VAL B N 1 ATOM 10039 C CA . VAL B 1 510 ? 77.944 63.633 68.025 1.00 29.41 ? 546 VAL B CA 1 ATOM 10040 C C . VAL B 1 510 ? 76.604 64.358 68.230 1.00 29.83 ? 546 VAL B C 1 ATOM 10041 O O . VAL B 1 510 ? 75.552 63.951 67.736 1.00 27.38 ? 546 VAL B O 1 ATOM 10042 C CB . VAL B 1 510 ? 78.687 64.208 66.782 1.00 32.60 ? 546 VAL B CB 1 ATOM 10043 C CG1 . VAL B 1 510 ? 79.109 63.106 65.873 1.00 33.76 ? 546 VAL B CG1 1 ATOM 10044 C CG2 . VAL B 1 510 ? 77.854 65.210 66.054 1.00 30.64 ? 546 VAL B CG2 1 ATOM 10045 N N . TYR B 1 511 ? 76.648 65.430 69.008 1.00 27.75 ? 547 TYR B N 1 ATOM 10046 C CA . TYR B 1 511 ? 75.558 66.386 68.992 1.00 26.24 ? 547 TYR B CA 1 ATOM 10047 C C . TYR B 1 511 ? 76.136 67.734 68.536 1.00 29.55 ? 547 TYR B C 1 ATOM 10048 O O . TYR B 1 511 ? 75.863 68.190 67.426 1.00 27.52 ? 547 TYR B O 1 ATOM 10049 C CB . TYR B 1 511 ? 74.832 66.464 70.346 1.00 28.20 ? 547 TYR B CB 1 ATOM 10050 C CG . TYR B 1 511 ? 73.648 67.382 70.253 1.00 29.40 ? 547 TYR B CG 1 ATOM 10051 C CD1 . TYR B 1 511 ? 72.488 66.988 69.589 1.00 27.30 ? 547 TYR B CD1 1 ATOM 10052 C CD2 . TYR B 1 511 ? 73.706 68.664 70.770 1.00 30.25 ? 547 TYR B CD2 1 ATOM 10053 C CE1 . TYR B 1 511 ? 71.410 67.853 69.461 1.00 30.17 ? 547 TYR B CE1 1 ATOM 10054 C CE2 . TYR B 1 511 ? 72.639 69.534 70.648 1.00 29.66 ? 547 TYR B CE2 1 ATOM 10055 C CZ . TYR B 1 511 ? 71.501 69.128 70.002 1.00 31.27 ? 547 TYR B CZ 1 ATOM 10056 O OH . TYR B 1 511 ? 70.458 70.011 69.899 1.00 33.61 ? 547 TYR B OH 1 ATOM 10057 N N . ALA B 1 512 ? 76.945 68.356 69.389 1.00 28.60 ? 548 ALA B N 1 ATOM 10058 C CA . ALA B 1 512 ? 77.741 69.516 69.006 1.00 23.10 ? 548 ALA B CA 1 ATOM 10059 C C . ALA B 1 512 ? 76.961 70.805 68.742 1.00 22.31 ? 548 ALA B C 1 ATOM 10060 O O . ALA B 1 512 ? 77.514 71.752 68.206 1.00 28.21 ? 548 ALA B O 1 ATOM 10061 C CB . ALA B 1 512 ? 78.632 69.178 67.814 1.00 26.62 ? 548 ALA B CB 1 ATOM 10062 N N . GLY B 1 513 ? 75.692 70.866 69.121 1.00 25.09 ? 549 GLY B N 1 ATOM 10063 C CA . GLY B 1 513 ? 74.960 72.119 68.994 1.00 25.07 ? 549 GLY B CA 1 ATOM 10064 C C . GLY B 1 513 ? 75.525 73.157 69.961 1.00 30.66 ? 549 GLY B C 1 ATOM 10065 O O . GLY B 1 513 ? 76.286 72.818 70.876 1.00 29.44 ? 549 GLY B O 1 ATOM 10066 N N . PRO B 1 514 ? 75.161 74.429 69.771 1.00 27.39 ? 550 PRO B N 1 ATOM 10067 C CA . PRO B 1 514 ? 75.713 75.501 70.610 1.00 26.32 ? 550 PRO B CA 1 ATOM 10068 C C . PRO B 1 514 ? 75.362 75.282 72.081 1.00 26.48 ? 550 PRO B C 1 ATOM 10069 O O . PRO B 1 514 ? 74.213 74.992 72.392 1.00 25.87 ? 550 PRO B O 1 ATOM 10070 C CB . PRO B 1 514 ? 75.003 76.753 70.086 1.00 27.09 ? 550 PRO B CB 1 ATOM 10071 C CG . PRO B 1 514 ? 74.563 76.395 68.698 1.00 28.69 ? 550 PRO B CG 1 ATOM 10072 C CD . PRO B 1 514 ? 74.207 74.943 68.777 1.00 25.52 ? 550 PRO B CD 1 ATOM 10073 N N . CYS B 1 515 ? 76.351 75.431 72.958 1.00 26.81 ? 551 CYS B N 1 ATOM 10074 C CA . CYS B 1 515 ? 76.216 75.192 74.396 1.00 26.44 ? 551 CYS B CA 1 ATOM 10075 C C . CYS B 1 515 ? 75.962 73.732 74.764 1.00 32.83 ? 551 CYS B C 1 ATOM 10076 O O . CYS B 1 515 ? 75.505 73.442 75.867 1.00 28.15 ? 551 CYS B O 1 ATOM 10077 C CB . CYS B 1 515 ? 75.154 76.090 75.026 1.00 28.72 ? 551 CYS B CB 1 ATOM 10078 S SG . CYS B 1 515 ? 75.452 76.374 76.799 1.00 34.44 ? 551 CYS B SG 1 ATOM 10079 N N . SER B 1 516 ? 76.288 72.809 73.862 1.00 29.89 ? 552 SER B N 1 ATOM 10080 C CA . SER B 1 516 ? 76.116 71.391 74.165 1.00 27.90 ? 552 SER B CA 1 ATOM 10081 C C . SER B 1 516 ? 77.257 70.856 75.008 1.00 27.30 ? 552 SER B C 1 ATOM 10082 O O . SER B 1 516 ? 78.316 71.468 75.116 1.00 29.97 ? 552 SER B O 1 ATOM 10083 C CB . SER B 1 516 ? 76.030 70.573 72.871 1.00 30.50 ? 552 SER B CB 1 ATOM 10084 O OG . SER B 1 516 ? 77.277 70.565 72.190 1.00 30.64 ? 552 SER B OG 1 ATOM 10085 N N . GLN B 1 517 ? 77.046 69.693 75.597 1.00 28.09 ? 553 GLN B N 1 ATOM 10086 C CA . GLN B 1 517 ? 78.101 69.047 76.347 1.00 30.45 ? 553 GLN B CA 1 ATOM 10087 C C . GLN B 1 517 ? 77.866 67.558 76.289 1.00 29.23 ? 553 GLN B C 1 ATOM 10088 O O . GLN B 1 517 ? 76.933 67.056 76.904 1.00 26.40 ? 553 GLN B O 1 ATOM 10089 C CB . GLN B 1 517 ? 78.126 69.516 77.804 1.00 27.48 ? 553 GLN B CB 1 ATOM 10090 C CG . GLN B 1 517 ? 79.183 68.810 78.639 1.00 29.21 ? 553 GLN B CG 1 ATOM 10091 C CD . GLN B 1 517 ? 79.382 69.452 80.004 1.00 33.56 ? 553 GLN B CD 1 ATOM 10092 O OE1 . GLN B 1 517 ? 78.535 69.339 80.898 1.00 30.23 ? 553 GLN B OE1 1 ATOM 10093 N NE2 . GLN B 1 517 ? 80.511 70.134 80.169 1.00 30.84 ? 553 GLN B NE2 1 ATOM 10094 N N . LYS B 1 518 ? 78.719 66.861 75.546 1.00 30.33 ? 554 LYS B N 1 ATOM 10095 C CA . LYS B 1 518 ? 78.597 65.417 75.368 1.00 30.73 ? 554 LYS B CA 1 ATOM 10096 C C . LYS B 1 518 ? 79.695 64.664 76.107 1.00 33.18 ? 554 LYS B C 1 ATOM 10097 O O . LYS B 1 518 ? 79.688 63.441 76.165 1.00 33.24 ? 554 LYS B O 1 ATOM 10098 C CB . LYS B 1 518 ? 78.609 65.066 73.886 1.00 30.76 ? 554 LYS B CB 1 ATOM 10099 C CG . LYS B 1 518 ? 77.327 65.480 73.169 1.00 35.13 ? 554 LYS B CG 1 ATOM 10100 C CD . LYS B 1 518 ? 76.227 64.440 73.382 1.00 34.81 ? 554 LYS B CD 1 ATOM 10101 C CE . LYS B 1 518 ? 76.458 63.216 72.474 1.00 35.08 ? 554 LYS B CE 1 ATOM 10102 N NZ . LYS B 1 518 ? 75.382 62.178 72.650 1.00 36.22 ? 554 LYS B NZ 1 ATOM 10103 N N . ALA B 1 519 ? 80.629 65.407 76.686 1.00 32.89 ? 555 ALA B N 1 ATOM 10104 C CA . ALA B 1 519 ? 81.647 64.820 77.536 1.00 33.23 ? 555 ALA B CA 1 ATOM 10105 C C . ALA B 1 519 ? 81.334 65.173 78.990 1.00 29.13 ? 555 ALA B C 1 ATOM 10106 O O . ALA B 1 519 ? 81.490 66.324 79.397 1.00 29.21 ? 555 ALA B O 1 ATOM 10107 C CB . ALA B 1 519 ? 83.006 65.348 77.138 1.00 32.89 ? 555 ALA B CB 1 ATOM 10108 N N . ASP B 1 520 ? 80.876 64.203 79.774 1.00 28.06 ? 556 ASP B N 1 ATOM 10109 C CA . ASP B 1 520 ? 80.537 64.496 81.174 1.00 29.98 ? 556 ASP B CA 1 ATOM 10110 C C . ASP B 1 520 ? 80.672 63.277 82.094 1.00 33.91 ? 556 ASP B C 1 ATOM 10111 O O . ASP B 1 520 ? 81.104 62.201 81.677 1.00 30.76 ? 556 ASP B O 1 ATOM 10112 C CB . ASP B 1 520 ? 79.129 65.090 81.280 1.00 30.38 ? 556 ASP B CB 1 ATOM 10113 C CG . ASP B 1 520 ? 78.040 64.106 80.863 1.00 36.53 ? 556 ASP B CG 1 ATOM 10114 O OD1 . ASP B 1 520 ? 78.269 62.872 80.960 1.00 34.46 ? 556 ASP B OD1 1 ATOM 10115 O OD2 . ASP B 1 520 ? 76.948 64.569 80.457 1.00 36.02 ? 556 ASP B OD2 1 ATOM 10116 N N . THR B 1 521 ? 80.288 63.435 83.349 1.00 29.32 ? 557 THR B N 1 ATOM 10117 C CA . THR B 1 521 ? 80.533 62.371 84.306 1.00 31.73 ? 557 THR B CA 1 ATOM 10118 C C . THR B 1 521 ? 79.273 61.583 84.653 1.00 30.84 ? 557 THR B C 1 ATOM 10119 O O . THR B 1 521 ? 79.261 60.845 85.639 1.00 33.62 ? 557 THR B O 1 ATOM 10120 C CB . THR B 1 521 ? 81.140 62.924 85.606 1.00 31.89 ? 557 THR B CB 1 ATOM 10121 O OG1 . THR B 1 521 ? 80.160 63.725 86.265 1.00 30.48 ? 557 THR B OG1 1 ATOM 10122 C CG2 . THR B 1 521 ? 82.361 63.782 85.315 1.00 28.88 ? 557 THR B CG2 1 ATOM 10123 N N . VAL B 1 522 ? 78.213 61.715 83.863 1.00 28.59 ? 558 VAL B N 1 ATOM 10124 C CA . VAL B 1 522 ? 76.987 61.001 84.218 1.00 30.20 ? 558 VAL B CA 1 ATOM 10125 C C . VAL B 1 522 ? 76.952 59.541 83.763 1.00 32.25 ? 558 VAL B C 1 ATOM 10126 O O . VAL B 1 522 ? 77.553 59.167 82.755 1.00 31.15 ? 558 VAL B O 1 ATOM 10127 C CB . VAL B 1 522 ? 75.675 61.762 83.850 1.00 35.30 ? 558 VAL B CB 1 ATOM 10128 C CG1 . VAL B 1 522 ? 75.931 63.256 83.661 1.00 33.11 ? 558 VAL B CG1 1 ATOM 10129 C CG2 . VAL B 1 522 ? 75.017 61.158 82.670 1.00 34.87 ? 558 VAL B CG2 1 ATOM 10130 N N . PHE B 1 523 ? 76.259 58.721 84.546 1.00 33.93 ? 559 PHE B N 1 ATOM 10131 C CA . PHE B 1 523 ? 76.153 57.301 84.284 1.00 32.52 ? 559 PHE B CA 1 ATOM 10132 C C . PHE B 1 523 ? 74.962 57.052 83.388 1.00 30.91 ? 559 PHE B C 1 ATOM 10133 O O . PHE B 1 523 ? 73.850 57.469 83.702 1.00 30.88 ? 559 PHE B O 1 ATOM 10134 C CB . PHE B 1 523 ? 75.971 56.537 85.584 1.00 30.55 ? 559 PHE B CB 1 ATOM 10135 C CG . PHE B 1 523 ? 75.735 55.070 85.399 1.00 34.01 ? 559 PHE B CG 1 ATOM 10136 C CD1 . PHE B 1 523 ? 76.795 54.207 85.170 1.00 36.71 ? 559 PHE B CD1 1 ATOM 10137 C CD2 . PHE B 1 523 ? 74.452 54.548 85.470 1.00 38.72 ? 559 PHE B CD2 1 ATOM 10138 C CE1 . PHE B 1 523 ? 76.576 52.840 85.012 1.00 40.08 ? 559 PHE B CE1 1 ATOM 10139 C CE2 . PHE B 1 523 ? 74.224 53.182 85.309 1.00 38.98 ? 559 PHE B CE2 1 ATOM 10140 C CZ . PHE B 1 523 ? 75.287 52.331 85.075 1.00 36.77 ? 559 PHE B CZ 1 ATOM 10141 N N . ARG B 1 524 ? 75.202 56.347 82.287 1.00 29.92 ? 560 ARG B N 1 ATOM 10142 C CA . ARG B 1 524 ? 74.158 56.068 81.298 1.00 29.42 ? 560 ARG B CA 1 ATOM 10143 C C . ARG B 1 524 ? 74.128 54.609 80.864 1.00 33.73 ? 560 ARG B C 1 ATOM 10144 O O . ARG B 1 524 ? 75.180 53.981 80.679 1.00 33.66 ? 560 ARG B O 1 ATOM 10145 C CB . ARG B 1 524 ? 74.359 56.951 80.064 1.00 26.33 ? 560 ARG B CB 1 ATOM 10146 C CG . ARG B 1 524 ? 74.051 58.408 80.312 1.00 31.82 ? 560 ARG B CG 1 ATOM 10147 C CD . ARG B 1 524 ? 74.232 59.266 79.074 1.00 34.07 ? 560 ARG B CD 1 ATOM 10148 N NE . ARG B 1 524 ? 73.935 60.669 79.351 1.00 36.45 ? 560 ARG B NE 1 ATOM 10149 C CZ . ARG B 1 524 ? 74.853 61.580 79.672 1.00 37.68 ? 560 ARG B CZ 1 ATOM 10150 N NH1 . ARG B 1 524 ? 76.131 61.239 79.764 1.00 35.08 ? 560 ARG B NH1 1 ATOM 10151 N NH2 . ARG B 1 524 ? 74.494 62.837 79.910 1.00 42.32 ? 560 ARG B NH2 1 ATOM 10152 N N . LEU B 1 525 ? 72.911 54.085 80.709 1.00 29.82 ? 561 LEU B N 1 ATOM 10153 C CA . LEU B 1 525 ? 72.665 52.797 80.074 1.00 30.01 ? 561 LEU B CA 1 ATOM 10154 C C . LEU B 1 525 ? 71.939 53.070 78.768 1.00 29.30 ? 561 LEU B C 1 ATOM 10155 O O . LEU B 1 525 ? 70.749 53.390 78.757 1.00 29.61 ? 561 LEU B O 1 ATOM 10156 C CB . LEU B 1 525 ? 71.805 51.910 80.972 1.00 34.75 ? 561 LEU B CB 1 ATOM 10157 C CG . LEU B 1 525 ? 72.466 51.488 82.285 1.00 34.58 ? 561 LEU B CG 1 ATOM 10158 C CD1 . LEU B 1 525 ? 71.457 50.790 83.197 1.00 31.58 ? 561 LEU B CD1 1 ATOM 10159 C CD2 . LEU B 1 525 ? 73.687 50.615 81.996 1.00 30.30 ? 561 LEU B CD2 1 ATOM 10160 N N . ASN B 1 526 ? 72.667 52.988 77.664 1.00 26.86 ? 562 ASN B N 1 ATOM 10161 C CA . ASN B 1 526 ? 72.089 53.335 76.378 1.00 29.98 ? 562 ASN B CA 1 ATOM 10162 C C . ASN B 1 526 ? 72.654 52.478 75.258 1.00 28.88 ? 562 ASN B C 1 ATOM 10163 O O . ASN B 1 526 ? 73.262 51.438 75.498 1.00 26.92 ? 562 ASN B O 1 ATOM 10164 C CB . ASN B 1 526 ? 72.302 54.824 76.068 1.00 25.92 ? 562 ASN B CB 1 ATOM 10165 C CG . ASN B 1 526 ? 73.761 55.231 76.134 1.00 29.29 ? 562 ASN B CG 1 ATOM 10166 O OD1 . ASN B 1 526 ? 74.662 54.388 76.115 1.00 28.19 ? 562 ASN B OD1 1 ATOM 10167 N ND2 . ASN B 1 526 ? 74.002 56.533 76.213 1.00 26.95 ? 562 ASN B ND2 1 ATOM 10168 N N . TRP B 1 527 ? 72.453 52.927 74.030 1.00 27.47 ? 563 TRP B N 1 ATOM 10169 C CA . TRP B 1 527 ? 72.849 52.144 72.872 1.00 26.27 ? 563 TRP B CA 1 ATOM 10170 C C . TRP B 1 527 ? 74.367 51.976 72.852 1.00 28.64 ? 563 TRP B C 1 ATOM 10171 O O . TRP B 1 527 ? 74.879 50.904 72.528 1.00 30.50 ? 563 TRP B O 1 ATOM 10172 C CB . TRP B 1 527 ? 72.329 52.815 71.606 1.00 24.41 ? 563 TRP B CB 1 ATOM 10173 C CG . TRP B 1 527 ? 72.549 52.044 70.347 1.00 28.06 ? 563 TRP B CG 1 ATOM 10174 C CD1 . TRP B 1 527 ? 72.220 50.735 70.106 1.00 25.26 ? 563 TRP B CD1 1 ATOM 10175 C CD2 . TRP B 1 527 ? 73.098 52.554 69.133 1.00 23.30 ? 563 TRP B CD2 1 ATOM 10176 N NE1 . TRP B 1 527 ? 72.561 50.398 68.818 1.00 24.97 ? 563 TRP B NE1 1 ATOM 10177 C CE2 . TRP B 1 527 ? 73.095 51.497 68.197 1.00 25.43 ? 563 TRP B CE2 1 ATOM 10178 C CE3 . TRP B 1 527 ? 73.595 53.802 68.744 1.00 24.84 ? 563 TRP B CE3 1 ATOM 10179 C CZ2 . TRP B 1 527 ? 73.571 51.648 66.902 1.00 23.85 ? 563 TRP B CZ2 1 ATOM 10180 C CZ3 . TRP B 1 527 ? 74.087 53.948 67.457 1.00 28.08 ? 563 TRP B CZ3 1 ATOM 10181 C CH2 . TRP B 1 527 ? 74.058 52.875 66.545 1.00 28.61 ? 563 TRP B CH2 1 ATOM 10182 N N . ALA B 1 528 ? 75.089 53.023 73.236 1.00 31.24 ? 564 ALA B N 1 ATOM 10183 C CA . ALA B 1 528 ? 76.549 52.960 73.255 1.00 30.86 ? 564 ALA B CA 1 ATOM 10184 C C . ALA B 1 528 ? 77.032 51.907 74.260 1.00 28.06 ? 564 ALA B C 1 ATOM 10185 O O . ALA B 1 528 ? 78.071 51.272 74.059 1.00 29.97 ? 564 ALA B O 1 ATOM 10186 C CB . ALA B 1 528 ? 77.142 54.330 73.571 1.00 28.85 ? 564 ALA B CB 1 ATOM 10187 N N . THR B 1 529 ? 76.279 51.721 75.335 1.00 28.72 ? 565 THR B N 1 ATOM 10188 C CA . THR B 1 529 ? 76.615 50.682 76.319 1.00 30.02 ? 565 THR B CA 1 ATOM 10189 C C . THR B 1 529 ? 76.608 49.309 75.644 1.00 30.76 ? 565 THR B C 1 ATOM 10190 O O . THR B 1 529 ? 77.525 48.512 75.812 1.00 30.68 ? 565 THR B O 1 ATOM 10191 C CB . THR B 1 529 ? 75.635 50.648 77.514 1.00 32.57 ? 565 THR B CB 1 ATOM 10192 O OG1 . THR B 1 529 ? 75.558 51.938 78.140 1.00 33.29 ? 565 THR B OG1 1 ATOM 10193 C CG2 . THR B 1 529 ? 76.097 49.611 78.552 1.00 29.86 ? 565 THR B CG2 1 ATOM 10194 N N . TYR B 1 530 ? 75.555 49.031 74.885 1.00 29.39 ? 566 TYR B N 1 ATOM 10195 C CA . TYR B 1 530 ? 75.490 47.815 74.093 1.00 27.55 ? 566 TYR B CA 1 ATOM 10196 C C . TYR B 1 530 ? 76.631 47.720 73.080 1.00 29.60 ? 566 TYR B C 1 ATOM 10197 O O . TYR B 1 530 ? 77.311 46.698 72.996 1.00 30.44 ? 566 TYR B O 1 ATOM 10198 C CB . TYR B 1 530 ? 74.134 47.711 73.383 1.00 28.98 ? 566 TYR B CB 1 ATOM 10199 C CG . TYR B 1 530 ? 74.203 47.006 72.054 1.00 31.01 ? 566 TYR B CG 1 ATOM 10200 C CD1 . TYR B 1 530 ? 74.397 45.627 71.985 1.00 32.09 ? 566 TYR B CD1 1 ATOM 10201 C CD2 . TYR B 1 530 ? 74.065 47.714 70.861 1.00 31.44 ? 566 TYR B CD2 1 ATOM 10202 C CE1 . TYR B 1 530 ? 74.458 44.971 70.747 1.00 35.21 ? 566 TYR B CE1 1 ATOM 10203 C CE2 . TYR B 1 530 ? 74.124 47.069 69.622 1.00 30.16 ? 566 TYR B CE2 1 ATOM 10204 C CZ . TYR B 1 530 ? 74.321 45.701 69.574 1.00 32.23 ? 566 TYR B CZ 1 ATOM 10205 O OH . TYR B 1 530 ? 74.380 45.058 68.353 1.00 36.75 ? 566 TYR B OH 1 ATOM 10206 N N . LEU B 1 531 ? 76.849 48.779 72.308 1.00 28.63 ? 567 LEU B N 1 ATOM 10207 C CA . LEU B 1 531 ? 77.897 48.747 71.295 1.00 28.52 ? 567 LEU B CA 1 ATOM 10208 C C . LEU B 1 531 ? 79.265 48.392 71.895 1.00 33.68 ? 567 LEU B C 1 ATOM 10209 O O . LEU B 1 531 ? 80.003 47.588 71.337 1.00 31.33 ? 567 LEU B O 1 ATOM 10210 C CB . LEU B 1 531 ? 77.966 50.074 70.531 1.00 27.16 ? 567 LEU B CB 1 ATOM 10211 C CG . LEU B 1 531 ? 76.782 50.402 69.599 1.00 25.41 ? 567 LEU B CG 1 ATOM 10212 C CD1 . LEU B 1 531 ? 76.880 51.838 69.110 1.00 26.33 ? 567 LEU B CD1 1 ATOM 10213 C CD2 . LEU B 1 531 ? 76.702 49.417 68.427 1.00 25.25 ? 567 LEU B CD2 1 ATOM 10214 N N . ALA B 1 532 ? 79.612 49.003 73.023 1.00 28.34 ? 568 ALA B N 1 ATOM 10215 C CA . ALA B 1 532 ? 80.909 48.739 73.642 1.00 28.22 ? 568 ALA B CA 1 ATOM 10216 C C . ALA B 1 532 ? 80.935 47.364 74.319 1.00 32.22 ? 568 ALA B C 1 ATOM 10217 O O . ALA B 1 532 ? 81.909 46.621 74.196 1.00 35.21 ? 568 ALA B O 1 ATOM 10218 C CB . ALA B 1 532 ? 81.256 49.840 74.662 1.00 28.03 ? 568 ALA B CB 1 ATOM 10219 N N . SER B 1 533 ? 79.866 47.025 75.035 1.00 27.63 ? 569 SER B N 1 ATOM 10220 C CA . SER B 1 533 ? 79.854 45.793 75.816 1.00 32.55 ? 569 SER B CA 1 ATOM 10221 C C . SER B 1 533 ? 79.775 44.534 74.945 1.00 35.69 ? 569 SER B C 1 ATOM 10222 O O . SER B 1 533 ? 80.481 43.559 75.189 1.00 35.42 ? 569 SER B O 1 ATOM 10223 C CB . SER B 1 533 ? 78.701 45.803 76.813 1.00 29.20 ? 569 SER B CB 1 ATOM 10224 O OG . SER B 1 533 ? 78.668 44.597 77.561 1.00 31.79 ? 569 SER B OG 1 ATOM 10225 N N . THR B 1 534 ? 78.916 44.564 73.932 1.00 32.85 ? 570 THR B N 1 ATOM 10226 C CA . THR B 1 534 ? 78.668 43.384 73.102 1.00 34.55 ? 570 THR B CA 1 ATOM 10227 C C . THR B 1 534 ? 79.435 43.361 71.774 1.00 34.67 ? 570 THR B C 1 ATOM 10228 O O . THR B 1 534 ? 79.823 42.295 71.301 1.00 39.47 ? 570 THR B O 1 ATOM 10229 C CB . THR B 1 534 ? 77.154 43.200 72.848 1.00 36.14 ? 570 THR B CB 1 ATOM 10230 O OG1 . THR B 1 534 ? 76.501 42.881 74.087 1.00 33.43 ? 570 THR B OG1 1 ATOM 10231 C CG2 . THR B 1 534 ? 76.891 42.086 71.830 1.00 34.28 ? 570 THR B CG2 1 ATOM 10232 N N . GLU B 1 535 ? 79.669 44.528 71.178 1.00 30.70 ? 571 GLU B N 1 ATOM 10233 C CA . GLU B 1 535 ? 80.272 44.594 69.850 1.00 34.51 ? 571 GLU B CA 1 ATOM 10234 C C . GLU B 1 535 ? 81.708 45.085 69.908 1.00 34.65 ? 571 GLU B C 1 ATOM 10235 O O . GLU B 1 535 ? 82.384 45.190 68.876 1.00 34.18 ? 571 GLU B O 1 ATOM 10236 C CB . GLU B 1 535 ? 79.446 45.501 68.931 1.00 33.33 ? 571 GLU B CB 1 ATOM 10237 C CG . GLU B 1 535 ? 77.996 45.081 68.834 1.00 34.94 ? 571 GLU B CG 1 ATOM 10238 C CD . GLU B 1 535 ? 77.829 43.689 68.234 1.00 44.35 ? 571 GLU B CD 1 ATOM 10239 O OE1 . GLU B 1 535 ? 78.738 43.237 67.495 1.00 42.36 ? 571 GLU B OE1 1 ATOM 10240 O OE2 . GLU B 1 535 ? 76.779 43.055 68.495 1.00 48.41 ? 571 GLU B OE2 1 ATOM 10241 N N . ASN B 1 536 ? 82.161 45.394 71.121 1.00 34.87 ? 572 ASN B N 1 ATOM 10242 C CA . ASN B 1 536 ? 83.539 45.801 71.362 1.00 31.66 ? 572 ASN B CA 1 ATOM 10243 C C . ASN B 1 536 ? 83.933 47.013 70.539 1.00 31.96 ? 572 ASN B C 1 ATOM 10244 O O . ASN B 1 536 ? 85.034 47.100 69.997 1.00 32.08 ? 572 ASN B O 1 ATOM 10245 C CB . ASN B 1 536 ? 84.480 44.620 71.142 1.00 32.06 ? 572 ASN B CB 1 ATOM 10246 C CG . ASN B 1 536 ? 84.204 43.491 72.126 1.00 40.93 ? 572 ASN B CG 1 ATOM 10247 O OD1 . ASN B 1 536 ? 84.393 43.649 73.337 1.00 39.21 ? 572 ASN B OD1 1 ATOM 10248 N ND2 . ASN B 1 536 ? 83.718 42.367 71.620 1.00 38.21 ? 572 ASN B ND2 1 ATOM 10249 N N . ILE B 1 537 ? 83.002 47.952 70.458 1.00 32.35 ? 573 ILE B N 1 ATOM 10250 C CA . ILE B 1 537 ? 83.209 49.212 69.761 1.00 28.49 ? 573 ILE B CA 1 ATOM 10251 C C . ILE B 1 537 ? 83.439 50.322 70.783 1.00 30.99 ? 573 ILE B C 1 ATOM 10252 O O . ILE B 1 537 ? 82.780 50.361 71.820 1.00 29.98 ? 573 ILE B O 1 ATOM 10253 C CB . ILE B 1 537 ? 81.972 49.560 68.925 1.00 33.19 ? 573 ILE B CB 1 ATOM 10254 C CG1 . ILE B 1 537 ? 81.720 48.454 67.898 1.00 30.35 ? 573 ILE B CG1 1 ATOM 10255 C CG2 . ILE B 1 537 ? 82.146 50.913 68.239 1.00 26.46 ? 573 ILE B CG2 1 ATOM 10256 C CD1 . ILE B 1 537 ? 80.393 48.563 67.203 1.00 31.81 ? 573 ILE B CD1 1 ATOM 10257 N N . ILE B 1 538 ? 84.391 51.209 70.507 1.00 31.87 ? 574 ILE B N 1 ATOM 10258 C CA . ILE B 1 538 ? 84.610 52.353 71.375 1.00 32.13 ? 574 ILE B CA 1 ATOM 10259 C C . ILE B 1 538 ? 83.644 53.398 70.887 1.00 31.77 ? 574 ILE B C 1 ATOM 10260 O O . ILE B 1 538 ? 83.600 53.667 69.695 1.00 32.36 ? 574 ILE B O 1 ATOM 10261 C CB . ILE B 1 538 ? 86.029 52.925 71.219 1.00 32.78 ? 574 ILE B CB 1 ATOM 10262 C CG1 . ILE B 1 538 ? 87.087 51.927 71.689 1.00 33.11 ? 574 ILE B CG1 1 ATOM 10263 C CG2 . ILE B 1 538 ? 86.176 54.221 71.998 1.00 33.03 ? 574 ILE B CG2 1 ATOM 10264 C CD1 . ILE B 1 538 ? 88.507 52.414 71.393 1.00 31.44 ? 574 ILE B CD1 1 ATOM 10265 N N . VAL B 1 539 ? 82.841 53.972 71.776 1.00 30.66 ? 575 VAL B N 1 ATOM 10266 C CA . VAL B 1 539 ? 81.979 55.073 71.351 1.00 29.04 ? 575 VAL B CA 1 ATOM 10267 C C . VAL B 1 539 ? 82.463 56.358 71.997 1.00 30.89 ? 575 VAL B C 1 ATOM 10268 O O . VAL B 1 539 ? 82.401 56.505 73.217 1.00 33.99 ? 575 VAL B O 1 ATOM 10269 C CB . VAL B 1 539 ? 80.517 54.860 71.737 1.00 30.09 ? 575 VAL B CB 1 ATOM 10270 C CG1 . VAL B 1 539 ? 79.670 56.010 71.190 1.00 27.29 ? 575 VAL B CG1 1 ATOM 10271 C CG2 . VAL B 1 539 ? 80.014 53.507 71.215 1.00 28.80 ? 575 VAL B CG2 1 ATOM 10272 N N . ALA B 1 540 ? 82.946 57.286 71.181 1.00 27.67 ? 576 ALA B N 1 ATOM 10273 C CA . ALA B 1 540 ? 83.512 58.523 71.692 1.00 27.98 ? 576 ALA B CA 1 ATOM 10274 C C . ALA B 1 540 ? 82.623 59.714 71.394 1.00 33.25 ? 576 ALA B C 1 ATOM 10275 O O . ALA B 1 540 ? 81.904 59.739 70.390 1.00 29.34 ? 576 ALA B O 1 ATOM 10276 C CB . ALA B 1 540 ? 84.886 58.750 71.111 1.00 28.56 ? 576 ALA B CB 1 ATOM 10277 N N . SER B 1 541 ? 82.679 60.704 72.276 1.00 30.66 ? 577 SER B N 1 ATOM 10278 C CA . SER B 1 541 ? 82.032 61.983 72.033 1.00 27.69 ? 577 SER B CA 1 ATOM 10279 C C . SER B 1 541 ? 83.021 63.087 72.364 1.00 32.86 ? 577 SER B C 1 ATOM 10280 O O . SER B 1 541 ? 83.856 62.927 73.255 1.00 29.56 ? 577 SER B O 1 ATOM 10281 C CB . SER B 1 541 ? 80.784 62.102 72.898 1.00 30.31 ? 577 SER B CB 1 ATOM 10282 O OG . SER B 1 541 ? 79.858 61.072 72.579 1.00 32.98 ? 577 SER B OG 1 ATOM 10283 N N . PHE B 1 542 ? 82.921 64.206 71.661 1.00 28.22 ? 578 PHE B N 1 ATOM 10284 C CA . PHE B 1 542 ? 83.886 65.290 71.803 1.00 30.34 ? 578 PHE B CA 1 ATOM 10285 C C . PHE B 1 542 ? 83.177 66.657 71.880 1.00 31.89 ? 578 PHE B C 1 ATOM 10286 O O . PHE B 1 542 ? 82.213 66.893 71.160 1.00 28.10 ? 578 PHE B O 1 ATOM 10287 C CB . PHE B 1 542 ? 84.872 65.239 70.621 1.00 28.80 ? 578 PHE B CB 1 ATOM 10288 C CG . PHE B 1 542 ? 85.823 66.398 70.563 1.00 29.87 ? 578 PHE B CG 1 ATOM 10289 C CD1 . PHE B 1 542 ? 86.912 66.459 71.415 1.00 32.39 ? 578 PHE B CD1 1 ATOM 10290 C CD2 . PHE B 1 542 ? 85.638 67.419 69.652 1.00 29.41 ? 578 PHE B CD2 1 ATOM 10291 C CE1 . PHE B 1 542 ? 87.792 67.518 71.362 1.00 29.53 ? 578 PHE B CE1 1 ATOM 10292 C CE2 . PHE B 1 542 ? 86.517 68.486 69.604 1.00 33.69 ? 578 PHE B CE2 1 ATOM 10293 C CZ . PHE B 1 542 ? 87.593 68.531 70.469 1.00 26.64 ? 578 PHE B CZ 1 ATOM 10294 N N . ASP B 1 543 ? 83.635 67.541 72.771 1.00 30.33 ? 579 ASP B N 1 ATOM 10295 C CA . ASP B 1 543 ? 83.068 68.890 72.877 1.00 29.74 ? 579 ASP B CA 1 ATOM 10296 C C . ASP B 1 543 ? 84.031 69.927 72.330 1.00 29.24 ? 579 ASP B C 1 ATOM 10297 O O . ASP B 1 543 ? 84.983 70.303 73.006 1.00 30.94 ? 579 ASP B O 1 ATOM 10298 C CB . ASP B 1 543 ? 82.781 69.251 74.339 1.00 29.90 ? 579 ASP B CB 1 ATOM 10299 C CG . ASP B 1 543 ? 81.669 68.420 74.939 1.00 34.16 ? 579 ASP B CG 1 ATOM 10300 O OD1 . ASP B 1 543 ? 80.719 68.061 74.197 1.00 33.29 ? 579 ASP B OD1 1 ATOM 10301 O OD2 . ASP B 1 543 ? 81.756 68.125 76.145 1.00 28.35 ? 579 ASP B OD2 1 ATOM 10302 N N . GLY B 1 544 ? 83.782 70.397 71.120 1.00 29.82 ? 580 GLY B N 1 ATOM 10303 C CA . GLY B 1 544 ? 84.683 71.328 70.474 1.00 29.36 ? 580 GLY B CA 1 ATOM 10304 C C . GLY B 1 544 ? 84.156 72.738 70.576 1.00 32.61 ? 580 GLY B C 1 ATOM 10305 O O . GLY B 1 544 ? 83.348 73.032 71.462 1.00 31.97 ? 580 GLY B O 1 ATOM 10306 N N . ARG B 1 545 ? 84.609 73.612 69.676 1.00 30.98 ? 581 ARG B N 1 ATOM 10307 C CA . ARG B 1 545 ? 84.114 74.981 69.643 1.00 28.76 ? 581 ARG B CA 1 ATOM 10308 C C . ARG B 1 545 ? 82.603 74.992 69.539 1.00 33.57 ? 581 ARG B C 1 ATOM 10309 O O . ARG B 1 545 ? 82.003 74.185 68.810 1.00 31.08 ? 581 ARG B O 1 ATOM 10310 C CB . ARG B 1 545 ? 84.749 75.784 68.510 1.00 28.57 ? 581 ARG B CB 1 ATOM 10311 C CG . ARG B 1 545 ? 86.141 76.283 68.886 1.00 36.01 ? 581 ARG B CG 1 ATOM 10312 C CD . ARG B 1 545 ? 86.887 76.904 67.722 1.00 34.18 ? 581 ARG B CD 1 ATOM 10313 N NE . ARG B 1 545 ? 87.330 75.892 66.770 1.00 36.07 ? 581 ARG B NE 1 ATOM 10314 C CZ . ARG B 1 545 ? 88.018 76.159 65.663 1.00 44.97 ? 581 ARG B CZ 1 ATOM 10315 N NH1 . ARG B 1 545 ? 88.352 77.413 65.374 1.00 42.16 ? 581 ARG B NH1 1 ATOM 10316 N NH2 . ARG B 1 545 ? 88.370 75.172 64.846 1.00 42.89 ? 581 ARG B NH2 1 ATOM 10317 N N . GLY B 1 546 ? 81.990 75.905 70.282 1.00 31.28 ? 582 GLY B N 1 ATOM 10318 C CA . GLY B 1 546 ? 80.550 75.965 70.354 1.00 30.04 ? 582 GLY B CA 1 ATOM 10319 C C . GLY B 1 546 ? 79.989 75.209 71.550 1.00 26.99 ? 582 GLY B C 1 ATOM 10320 O O . GLY B 1 546 ? 78.837 75.416 71.897 1.00 28.66 ? 582 GLY B O 1 ATOM 10321 N N . SER B 1 547 ? 80.767 74.331 72.182 1.00 26.20 ? 583 SER B N 1 ATOM 10322 C CA . SER B 1 547 ? 80.238 73.624 73.345 1.00 25.54 ? 583 SER B CA 1 ATOM 10323 C C . SER B 1 547 ? 80.082 74.584 74.543 1.00 30.75 ? 583 SER B C 1 ATOM 10324 O O . SER B 1 547 ? 80.631 75.681 74.536 1.00 30.03 ? 583 SER B O 1 ATOM 10325 C CB . SER B 1 547 ? 81.096 72.415 73.712 1.00 28.83 ? 583 SER B CB 1 ATOM 10326 O OG . SER B 1 547 ? 82.466 72.756 73.848 1.00 31.93 ? 583 SER B OG 1 ATOM 10327 N N . GLY B 1 548 ? 79.330 74.180 75.566 1.00 29.57 ? 584 GLY B N 1 ATOM 10328 C CA . GLY B 1 548 ? 78.991 75.101 76.645 1.00 28.04 ? 584 GLY B CA 1 ATOM 10329 C C . GLY B 1 548 ? 79.791 74.902 77.922 1.00 28.22 ? 584 GLY B C 1 ATOM 10330 O O . GLY B 1 548 ? 80.623 73.995 78.006 1.00 25.29 ? 584 GLY B O 1 ATOM 10331 N N . TYR B 1 549 ? 79.549 75.771 78.903 1.00 29.46 ? 585 TYR B N 1 ATOM 10332 C CA . TYR B 1 549 ? 80.078 75.607 80.264 1.00 26.79 ? 585 TYR B CA 1 ATOM 10333 C C . TYR B 1 549 ? 81.583 75.786 80.409 1.00 30.23 ? 585 TYR B C 1 ATOM 10334 O O . TYR B 1 549 ? 82.149 75.423 81.441 1.00 34.25 ? 585 TYR B O 1 ATOM 10335 C CB . TYR B 1 549 ? 79.634 74.265 80.862 1.00 27.37 ? 585 TYR B CB 1 ATOM 10336 C CG . TYR B 1 549 ? 78.185 73.986 80.569 1.00 29.22 ? 585 TYR B CG 1 ATOM 10337 C CD1 . TYR B 1 549 ? 77.186 74.744 81.161 1.00 25.93 ? 585 TYR B CD1 1 ATOM 10338 C CD2 . TYR B 1 549 ? 77.813 73.002 79.655 1.00 28.01 ? 585 TYR B CD2 1 ATOM 10339 C CE1 . TYR B 1 549 ? 75.843 74.516 80.884 1.00 25.26 ? 585 TYR B CE1 1 ATOM 10340 C CE2 . TYR B 1 549 ? 76.463 72.770 79.363 1.00 27.49 ? 585 TYR B CE2 1 ATOM 10341 C CZ . TYR B 1 549 ? 75.488 73.528 79.985 1.00 28.22 ? 585 TYR B CZ 1 ATOM 10342 O OH . TYR B 1 549 ? 74.155 73.308 79.722 1.00 29.12 ? 585 TYR B OH 1 ATOM 10343 N N . GLN B 1 550 ? 82.212 76.384 79.399 1.00 29.48 ? 586 GLN B N 1 ATOM 10344 C CA . GLN B 1 550 ? 83.658 76.594 79.377 1.00 29.44 ? 586 GLN B CA 1 ATOM 10345 C C . GLN B 1 550 ? 84.011 78.031 78.991 1.00 29.56 ? 586 GLN B C 1 ATOM 10346 O O . GLN B 1 550 ? 85.160 78.324 78.644 1.00 30.52 ? 586 GLN B O 1 ATOM 10347 C CB . GLN B 1 550 ? 84.297 75.642 78.366 1.00 30.11 ? 586 GLN B CB 1 ATOM 10348 C CG . GLN B 1 550 ? 84.065 74.184 78.660 1.00 31.07 ? 586 GLN B CG 1 ATOM 10349 C CD . GLN B 1 550 ? 84.184 73.341 77.408 1.00 33.87 ? 586 GLN B CD 1 ATOM 10350 O OE1 . GLN B 1 550 ? 83.182 73.044 76.760 1.00 33.04 ? 586 GLN B OE1 1 ATOM 10351 N NE2 . GLN B 1 550 ? 85.410 72.987 77.040 1.00 29.30 ? 586 GLN B NE2 1 ATOM 10352 N N . GLY B 1 551 ? 83.023 78.921 79.021 1.00 30.22 ? 587 GLY B N 1 ATOM 10353 C CA . GLY B 1 551 ? 83.272 80.317 78.701 1.00 31.56 ? 587 GLY B CA 1 ATOM 10354 C C . GLY B 1 551 ? 82.857 80.706 77.297 1.00 32.37 ? 587 GLY B C 1 ATOM 10355 O O . GLY B 1 551 ? 82.719 79.848 76.414 1.00 30.89 ? 587 GLY B O 1 ATOM 10356 N N . ASP B 1 552 ? 82.665 82.004 77.087 1.00 29.74 ? 588 ASP B N 1 ATOM 10357 C CA . ASP B 1 552 ? 82.182 82.511 75.808 1.00 34.80 ? 588 ASP B CA 1 ATOM 10358 C C . ASP B 1 552 ? 83.203 82.393 74.679 1.00 34.29 ? 588 ASP B C 1 ATOM 10359 O O . ASP B 1 552 ? 82.831 82.310 73.514 1.00 34.37 ? 588 ASP B O 1 ATOM 10360 C CB . ASP B 1 552 ? 81.700 83.961 75.928 1.00 32.39 ? 588 ASP B CB 1 ATOM 10361 C CG . ASP B 1 552 ? 80.355 84.067 76.615 1.00 39.95 ? 588 ASP B CG 1 ATOM 10362 O OD1 . ASP B 1 552 ? 79.715 83.009 76.804 1.00 38.67 ? 588 ASP B OD1 1 ATOM 10363 O OD2 . ASP B 1 552 ? 79.935 85.199 76.957 1.00 40.53 ? 588 ASP B OD2 1 ATOM 10364 N N . LYS B 1 553 ? 84.488 82.385 75.000 1.00 32.74 ? 589 LYS B N 1 ATOM 10365 C CA . LYS B 1 553 ? 85.452 82.260 73.925 1.00 33.69 ? 589 LYS B CA 1 ATOM 10366 C C . LYS B 1 553 ? 85.158 80.969 73.154 1.00 36.08 ? 589 LYS B C 1 ATOM 10367 O O . LYS B 1 553 ? 85.125 80.966 71.929 1.00 30.47 ? 589 LYS B O 1 ATOM 10368 C CB . LYS B 1 553 ? 86.897 82.297 74.422 1.00 34.49 ? 589 LYS B CB 1 ATOM 10369 C CG . LYS B 1 553 ? 87.898 82.390 73.247 1.00 36.61 ? 589 LYS B CG 1 ATOM 10370 C CD . LYS B 1 553 ? 89.345 82.238 73.693 1.00 46.19 ? 589 LYS B CD 1 ATOM 10371 N N . ILE B 1 554 ? 84.899 79.885 73.880 1.00 32.49 ? 590 ILE B N 1 ATOM 10372 C CA . ILE B 1 554 ? 84.559 78.613 73.249 1.00 31.20 ? 590 ILE B CA 1 ATOM 10373 C C . ILE B 1 554 ? 83.126 78.596 72.700 1.00 30.60 ? 590 ILE B C 1 ATOM 10374 O O . ILE B 1 554 ? 82.899 78.206 71.562 1.00 30.25 ? 590 ILE B O 1 ATOM 10375 C CB . ILE B 1 554 ? 84.828 77.421 74.213 1.00 31.50 ? 590 ILE B CB 1 ATOM 10376 C CG1 . ILE B 1 554 ? 86.332 77.110 74.242 1.00 35.08 ? 590 ILE B CG1 1 ATOM 10377 C CG2 . ILE B 1 554 ? 84.034 76.188 73.801 1.00 30.67 ? 590 ILE B CG2 1 ATOM 10378 C CD1 . ILE B 1 554 ? 86.779 76.276 75.442 1.00 35.13 ? 590 ILE B CD1 1 ATOM 10379 N N . MET B 1 555 ? 82.157 79.031 73.494 1.00 29.12 ? 591 MET B N 1 ATOM 10380 C CA . MET B 1 555 ? 80.766 78.893 73.088 1.00 32.72 ? 591 MET B CA 1 ATOM 10381 C C . MET B 1 555 ? 80.367 79.776 71.910 1.00 32.20 ? 591 MET B C 1 ATOM 10382 O O . MET B 1 555 ? 79.602 79.337 71.045 1.00 31.25 ? 591 MET B O 1 ATOM 10383 C CB . MET B 1 555 ? 79.824 79.150 74.249 1.00 30.66 ? 591 MET B CB 1 ATOM 10384 C CG . MET B 1 555 ? 78.381 78.827 73.920 1.00 33.75 ? 591 MET B CG 1 ATOM 10385 S SD . MET B 1 555 ? 77.353 79.012 75.385 1.00 37.42 ? 591 MET B SD 1 ATOM 10386 C CE . MET B 1 555 ? 77.009 80.767 75.343 1.00 31.66 ? 591 MET B CE 1 ATOM 10387 N N . HIS B 1 556 ? 80.876 81.008 71.876 1.00 30.71 ? 592 HIS B N 1 ATOM 10388 C CA . HIS B 1 556 ? 80.530 81.951 70.806 1.00 31.42 ? 592 HIS B CA 1 ATOM 10389 C C . HIS B 1 556 ? 81.390 81.839 69.552 1.00 31.41 ? 592 HIS B C 1 ATOM 10390 O O . HIS B 1 556 ? 81.181 82.579 68.592 1.00 31.60 ? 592 HIS B O 1 ATOM 10391 C CB . HIS B 1 556 ? 80.565 83.391 71.321 1.00 32.74 ? 592 HIS B CB 1 ATOM 10392 C CG . HIS B 1 556 ? 79.450 83.721 72.269 1.00 34.18 ? 592 HIS B CG 1 ATOM 10393 N ND1 . HIS B 1 556 ? 79.430 84.872 73.027 1.00 36.08 ? 592 HIS B ND1 1 ATOM 10394 C CD2 . HIS B 1 556 ? 78.317 83.048 72.578 1.00 29.75 ? 592 HIS B CD2 1 ATOM 10395 C CE1 . HIS B 1 556 ? 78.336 84.891 73.768 1.00 33.99 ? 592 HIS B CE1 1 ATOM 10396 N NE2 . HIS B 1 556 ? 77.639 83.799 73.507 1.00 31.76 ? 592 HIS B NE2 1 ATOM 10397 N N . ALA B 1 557 ? 82.349 80.918 69.546 1.00 31.17 ? 593 ALA B N 1 ATOM 10398 C CA . ALA B 1 557 ? 83.222 80.747 68.378 1.00 35.22 ? 593 ALA B CA 1 ATOM 10399 C C . ALA B 1 557 ? 82.390 80.489 67.125 1.00 33.91 ? 593 ALA B C 1 ATOM 10400 O O . ALA B 1 557 ? 82.794 80.786 66.007 1.00 33.37 ? 593 ALA B O 1 ATOM 10401 C CB . ALA B 1 557 ? 84.197 79.606 68.614 1.00 34.87 ? 593 ALA B CB 1 ATOM 10402 N N . ILE B 1 558 ? 81.203 79.955 67.349 1.00 31.65 ? 594 ILE B N 1 ATOM 10403 C CA . ILE B 1 558 ? 80.312 79.501 66.298 1.00 32.36 ? 594 ILE B CA 1 ATOM 10404 C C . ILE B 1 558 ? 79.321 80.577 65.864 1.00 33.83 ? 594 ILE B C 1 ATOM 10405 O O . ILE B 1 558 ? 78.493 80.354 64.995 1.00 33.47 ? 594 ILE B O 1 ATOM 10406 C CB . ILE B 1 558 ? 79.524 78.304 66.835 1.00 38.61 ? 594 ILE B CB 1 ATOM 10407 C CG1 . ILE B 1 558 ? 79.597 77.170 65.843 1.00 39.77 ? 594 ILE B CG1 1 ATOM 10408 C CG2 . ILE B 1 558 ? 78.118 78.710 67.314 1.00 37.42 ? 594 ILE B CG2 1 ATOM 10409 C CD1 . ILE B 1 558 ? 81.009 76.699 65.693 1.00 37.54 ? 594 ILE B CD1 1 ATOM 10410 N N . ASN B 1 559 ? 79.395 81.739 66.491 1.00 31.87 ? 595 ASN B N 1 ATOM 10411 C CA . ASN B 1 559 ? 78.426 82.797 66.257 1.00 31.68 ? 595 ASN B CA 1 ATOM 10412 C C . ASN B 1 559 ? 78.290 83.147 64.770 1.00 33.27 ? 595 ASN B C 1 ATOM 10413 O O . ASN B 1 559 ? 79.287 83.379 64.083 1.00 31.80 ? 595 ASN B O 1 ATOM 10414 C CB . ASN B 1 559 ? 78.831 84.032 67.057 1.00 31.09 ? 595 ASN B CB 1 ATOM 10415 C CG . ASN B 1 559 ? 77.836 85.141 66.944 1.00 35.29 ? 595 ASN B CG 1 ATOM 10416 O OD1 . ASN B 1 559 ? 76.633 84.911 67.014 1.00 35.62 ? 595 ASN B OD1 1 ATOM 10417 N ND2 . ASN B 1 559 ? 78.328 86.361 66.756 1.00 35.77 ? 595 ASN B ND2 1 ATOM 10418 N N . ARG B 1 560 ? 77.050 83.169 64.286 1.00 30.89 ? 596 ARG B N 1 ATOM 10419 C CA . ARG B 1 560 ? 76.730 83.477 62.882 1.00 34.76 ? 596 ARG B CA 1 ATOM 10420 C C . ARG B 1 560 ? 77.359 82.511 61.868 1.00 32.64 ? 596 ARG B C 1 ATOM 10421 O O . ARG B 1 560 ? 77.312 82.749 60.669 1.00 34.35 ? 596 ARG B O 1 ATOM 10422 C CB . ARG B 1 560 ? 77.082 84.932 62.547 1.00 35.18 ? 596 ARG B CB 1 ATOM 10423 C CG . ARG B 1 560 ? 76.352 85.938 63.426 1.00 37.70 ? 596 ARG B CG 1 ATOM 10424 C CD . ARG B 1 560 ? 76.689 87.376 63.099 1.00 42.90 ? 596 ARG B CD 1 ATOM 10425 N NE . ARG B 1 560 ? 76.022 87.844 61.884 1.00 48.28 ? 596 ARG B NE 1 ATOM 10426 C CZ . ARG B 1 560 ? 76.645 88.025 60.725 1.00 51.69 ? 596 ARG B CZ 1 ATOM 10427 N NH1 . ARG B 1 560 ? 77.954 87.785 60.633 1.00 54.66 ? 596 ARG B NH1 1 ATOM 10428 N NH2 . ARG B 1 560 ? 75.970 88.457 59.662 1.00 49.97 ? 596 ARG B NH2 1 ATOM 10429 N N . ARG B 1 561 ? 77.933 81.416 62.359 1.00 31.73 ? 597 ARG B N 1 ATOM 10430 C CA . ARG B 1 561 ? 78.675 80.497 61.505 1.00 34.03 ? 597 ARG B CA 1 ATOM 10431 C C . ARG B 1 561 ? 78.434 79.034 61.857 1.00 34.10 ? 597 ARG B C 1 ATOM 10432 O O . ARG B 1 561 ? 79.389 78.272 61.991 1.00 37.43 ? 597 ARG B O 1 ATOM 10433 C CB . ARG B 1 561 ? 80.172 80.785 61.620 1.00 36.91 ? 597 ARG B CB 1 ATOM 10434 C CG . ARG B 1 561 ? 80.598 82.131 61.050 1.00 41.48 ? 597 ARG B CG 1 ATOM 10435 C CD . ARG B 1 561 ? 80.519 82.097 59.529 1.00 41.06 ? 597 ARG B CD 1 ATOM 10436 N NE . ARG B 1 561 ? 80.896 83.361 58.898 1.00 48.22 ? 597 ARG B NE 1 ATOM 10437 C CZ . ARG B 1 561 ? 80.066 84.382 58.702 1.00 47.06 ? 597 ARG B CZ 1 ATOM 10438 N NH1 . ARG B 1 561 ? 80.500 85.489 58.113 1.00 51.64 ? 597 ARG B NH1 1 ATOM 10439 N NH2 . ARG B 1 561 ? 78.807 84.307 59.104 1.00 41.98 ? 597 ARG B NH2 1 ATOM 10440 N N . LEU B 1 562 ? 77.175 78.633 62.013 1.00 31.81 ? 598 LEU B N 1 ATOM 10441 C CA . LEU B 1 562 ? 76.875 77.224 62.278 1.00 33.13 ? 598 LEU B CA 1 ATOM 10442 C C . LEU B 1 562 ? 77.387 76.375 61.120 1.00 32.73 ? 598 LEU B C 1 ATOM 10443 O O . LEU B 1 562 ? 77.449 76.841 59.981 1.00 30.35 ? 598 LEU B O 1 ATOM 10444 C CB . LEU B 1 562 ? 75.369 76.999 62.469 1.00 30.49 ? 598 LEU B CB 1 ATOM 10445 C CG . LEU B 1 562 ? 74.672 77.816 63.558 1.00 29.78 ? 598 LEU B CG 1 ATOM 10446 C CD1 . LEU B 1 562 ? 73.230 77.374 63.718 1.00 24.42 ? 598 LEU B CD1 1 ATOM 10447 C CD2 . LEU B 1 562 ? 75.412 77.699 64.881 1.00 27.73 ? 598 LEU B CD2 1 ATOM 10448 N N . GLY B 1 563 ? 77.766 75.134 61.409 1.00 31.44 ? 599 GLY B N 1 ATOM 10449 C CA . GLY B 1 563 ? 78.274 74.241 60.377 1.00 28.88 ? 599 GLY B CA 1 ATOM 10450 C C . GLY B 1 563 ? 79.706 74.538 59.949 1.00 33.80 ? 599 GLY B C 1 ATOM 10451 O O . GLY B 1 563 ? 80.112 74.158 58.855 1.00 28.54 ? 599 GLY B O 1 ATOM 10452 N N . THR B 1 564 ? 80.480 75.201 60.810 1.00 29.20 ? 600 THR B N 1 ATOM 10453 C CA . THR B 1 564 ? 81.886 75.463 60.514 1.00 29.54 ? 600 THR B CA 1 ATOM 10454 C C . THR B 1 564 ? 82.831 74.829 61.536 1.00 33.93 ? 600 THR B C 1 ATOM 10455 O O . THR B 1 564 ? 83.274 73.690 61.348 1.00 33.07 ? 600 THR B O 1 ATOM 10456 C CB . THR B 1 564 ? 82.183 76.975 60.386 1.00 32.03 ? 600 THR B CB 1 ATOM 10457 O OG1 . THR B 1 564 ? 81.994 77.613 61.650 1.00 32.12 ? 600 THR B OG1 1 ATOM 10458 C CG2 . THR B 1 564 ? 81.254 77.618 59.376 1.00 33.80 ? 600 THR B CG2 1 ATOM 10459 N N . PHE B 1 565 ? 83.137 75.562 62.610 1.00 31.18 ? 601 PHE B N 1 ATOM 10460 C CA . PHE B 1 565 ? 84.125 75.126 63.592 1.00 31.57 ? 601 PHE B CA 1 ATOM 10461 C C . PHE B 1 565 ? 83.709 73.872 64.366 1.00 32.70 ? 601 PHE B C 1 ATOM 10462 O O . PHE B 1 565 ? 84.556 73.059 64.744 1.00 31.38 ? 601 PHE B O 1 ATOM 10463 C CB . PHE B 1 565 ? 84.448 76.269 64.568 1.00 31.09 ? 601 PHE B CB 1 ATOM 10464 C CG . PHE B 1 565 ? 85.074 77.475 63.906 1.00 36.06 ? 601 PHE B CG 1 ATOM 10465 C CD1 . PHE B 1 565 ? 86.169 77.333 63.067 1.00 36.74 ? 601 PHE B CD1 1 ATOM 10466 C CD2 . PHE B 1 565 ? 84.559 78.745 64.113 1.00 39.07 ? 601 PHE B CD2 1 ATOM 10467 C CE1 . PHE B 1 565 ? 86.743 78.441 62.447 1.00 41.15 ? 601 PHE B CE1 1 ATOM 10468 C CE2 . PHE B 1 565 ? 85.126 79.855 63.498 1.00 44.16 ? 601 PHE B CE2 1 ATOM 10469 C CZ . PHE B 1 565 ? 86.223 79.703 62.664 1.00 40.57 ? 601 PHE B CZ 1 ATOM 10470 N N . GLU B 1 566 ? 82.416 73.705 64.624 1.00 30.66 ? 602 GLU B N 1 ATOM 10471 C CA . GLU B 1 566 ? 81.998 72.531 65.389 1.00 32.12 ? 602 GLU B CA 1 ATOM 10472 C C . GLU B 1 566 ? 82.105 71.256 64.539 1.00 30.22 ? 602 GLU B C 1 ATOM 10473 O O . GLU B 1 566 ? 82.328 70.163 65.066 1.00 31.61 ? 602 GLU B O 1 ATOM 10474 C CB . GLU B 1 566 ? 80.601 72.703 66.023 1.00 30.33 ? 602 GLU B CB 1 ATOM 10475 C CG . GLU B 1 566 ? 79.419 72.482 65.081 1.00 27.46 ? 602 GLU B CG 1 ATOM 10476 C CD . GLU B 1 566 ? 79.172 73.660 64.158 1.00 33.69 ? 602 GLU B CD 1 ATOM 10477 O OE1 . GLU B 1 566 ? 80.157 74.330 63.768 1.00 34.23 ? 602 GLU B OE1 1 ATOM 10478 O OE2 . GLU B 1 566 ? 77.993 73.919 63.822 1.00 34.87 ? 602 GLU B OE2 1 ATOM 10479 N N . VAL B 1 567 ? 81.979 71.410 63.225 1.00 32.33 ? 603 VAL B N 1 ATOM 10480 C CA . VAL B 1 567 ? 82.128 70.296 62.271 1.00 29.42 ? 603 VAL B CA 1 ATOM 10481 C C . VAL B 1 567 ? 83.606 69.960 62.074 1.00 30.86 ? 603 VAL B C 1 ATOM 10482 O O . VAL B 1 567 ? 84.023 68.804 62.118 1.00 29.43 ? 603 VAL B O 1 ATOM 10483 C CB . VAL B 1 567 ? 81.552 70.683 60.901 1.00 27.79 ? 603 VAL B CB 1 ATOM 10484 C CG1 . VAL B 1 567 ? 81.728 69.539 59.895 1.00 32.48 ? 603 VAL B CG1 1 ATOM 10485 C CG2 . VAL B 1 567 ? 80.093 71.054 61.022 1.00 28.83 ? 603 VAL B CG2 1 ATOM 10486 N N . GLU B 1 568 ? 84.387 71.003 61.839 1.00 30.50 ? 604 GLU B N 1 ATOM 10487 C CA . GLU B 1 568 ? 85.831 70.915 61.736 1.00 34.02 ? 604 GLU B CA 1 ATOM 10488 C C . GLU B 1 568 ? 86.421 70.246 62.980 1.00 36.63 ? 604 GLU B C 1 ATOM 10489 O O . GLU B 1 568 ? 87.307 69.392 62.878 1.00 33.55 ? 604 GLU B O 1 ATOM 10490 C CB . GLU B 1 568 ? 86.364 72.336 61.605 1.00 38.77 ? 604 GLU B CB 1 ATOM 10491 C CG . GLU B 1 568 ? 87.705 72.476 60.944 1.00 51.65 ? 604 GLU B CG 1 ATOM 10492 C CD . GLU B 1 568 ? 88.142 73.931 60.877 1.00 55.58 ? 604 GLU B CD 1 ATOM 10493 O OE1 . GLU B 1 568 ? 87.360 74.769 60.356 1.00 52.27 ? 604 GLU B OE1 1 ATOM 10494 O OE2 . GLU B 1 568 ? 89.254 74.230 61.365 1.00 54.77 ? 604 GLU B OE2 1 ATOM 10495 N N . ASP B 1 569 ? 85.916 70.619 64.158 1.00 33.47 ? 605 ASP B N 1 ATOM 10496 C CA . ASP B 1 569 ? 86.459 70.101 65.414 1.00 33.38 ? 605 ASP B CA 1 ATOM 10497 C C . ASP B 1 569 ? 86.127 68.629 65.663 1.00 31.76 ? 605 ASP B C 1 ATOM 10498 O O . ASP B 1 569 ? 86.943 67.893 66.203 1.00 30.31 ? 605 ASP B O 1 ATOM 10499 C CB . ASP B 1 569 ? 86.022 70.963 66.600 1.00 36.68 ? 605 ASP B CB 1 ATOM 10500 C CG . ASP B 1 569 ? 86.719 72.322 66.624 1.00 42.52 ? 605 ASP B CG 1 ATOM 10501 O OD1 . ASP B 1 569 ? 87.641 72.544 65.801 1.00 42.30 ? 605 ASP B OD1 1 ATOM 10502 O OD2 . ASP B 1 569 ? 86.341 73.160 67.474 1.00 39.99 ? 605 ASP B OD2 1 ATOM 10503 N N . GLN B 1 570 ? 84.939 68.196 65.261 1.00 32.81 ? 606 GLN B N 1 ATOM 10504 C CA . GLN B 1 570 ? 84.624 66.772 65.301 1.00 30.05 ? 606 GLN B CA 1 ATOM 10505 C C . GLN B 1 570 ? 85.586 65.970 64.409 1.00 30.32 ? 606 GLN B C 1 ATOM 10506 O O . GLN B 1 570 ? 86.044 64.890 64.794 1.00 33.36 ? 606 GLN B O 1 ATOM 10507 C CB . GLN B 1 570 ? 83.161 66.523 64.916 1.00 32.72 ? 606 GLN B CB 1 ATOM 10508 C CG . GLN B 1 570 ? 82.177 67.127 65.910 1.00 26.25 ? 606 GLN B CG 1 ATOM 10509 C CD . GLN B 1 570 ? 82.207 66.414 67.236 1.00 28.40 ? 606 GLN B CD 1 ATOM 10510 O OE1 . GLN B 1 570 ? 82.150 65.187 67.294 1.00 31.34 ? 606 GLN B OE1 1 ATOM 10511 N NE2 . GLN B 1 570 ? 82.293 67.176 68.317 1.00 29.79 ? 606 GLN B NE2 1 ATOM 10512 N N . ILE B 1 571 ? 85.911 66.506 63.235 1.00 29.18 ? 607 ILE B N 1 ATOM 10513 C CA . ILE B 1 571 ? 86.867 65.849 62.333 1.00 30.36 ? 607 ILE B CA 1 ATOM 10514 C C . ILE B 1 571 ? 88.269 65.740 62.966 1.00 34.37 ? 607 ILE B C 1 ATOM 10515 O O . ILE B 1 571 ? 88.881 64.675 62.957 1.00 34.82 ? 607 ILE B O 1 ATOM 10516 C CB . ILE B 1 571 ? 86.938 66.568 60.973 1.00 33.25 ? 607 ILE B CB 1 ATOM 10517 C CG1 . ILE B 1 571 ? 85.572 66.506 60.280 1.00 28.83 ? 607 ILE B CG1 1 ATOM 10518 C CG2 . ILE B 1 571 ? 88.027 65.945 60.078 1.00 36.54 ? 607 ILE B CG2 1 ATOM 10519 C CD1 . ILE B 1 571 ? 85.475 67.298 58.985 1.00 32.84 ? 607 ILE B CD1 1 ATOM 10520 N N . GLU B 1 572 ? 88.758 66.836 63.539 1.00 35.29 ? 608 GLU B N 1 ATOM 10521 C CA . GLU B 1 572 ? 90.078 66.850 64.169 1.00 36.28 ? 608 GLU B CA 1 ATOM 10522 C C . GLU B 1 572 ? 90.151 65.882 65.365 1.00 36.55 ? 608 GLU B C 1 ATOM 10523 O O . GLU B 1 572 ? 91.169 65.218 65.578 1.00 39.68 ? 608 GLU B O 1 ATOM 10524 C CB . GLU B 1 572 ? 90.458 68.279 64.587 1.00 37.07 ? 608 GLU B CB 1 ATOM 10525 C CG . GLU B 1 572 ? 91.895 68.424 65.077 1.00 40.83 ? 608 GLU B CG 1 ATOM 10526 C CD . GLU B 1 572 ? 92.904 67.754 64.142 1.00 52.39 ? 608 GLU B CD 1 ATOM 10527 O OE1 . GLU B 1 572 ? 92.694 67.809 62.902 1.00 49.26 ? 608 GLU B OE1 1 ATOM 10528 O OE2 . GLU B 1 572 ? 93.899 67.171 64.650 1.00 53.52 ? 608 GLU B OE2 1 ATOM 10529 N N . ALA B 1 573 ? 89.064 65.785 66.128 1.00 34.05 ? 609 ALA B N 1 ATOM 10530 C CA . ALA B 1 573 ? 89.015 64.884 67.276 1.00 34.83 ? 609 ALA B CA 1 ATOM 10531 C C . ALA B 1 573 ? 89.182 63.447 66.819 1.00 36.67 ? 609 ALA B C 1 ATOM 10532 O O . ALA B 1 573 ? 89.901 62.671 67.438 1.00 37.58 ? 609 ALA B O 1 ATOM 10533 C CB . ALA B 1 573 ? 87.712 65.047 68.031 1.00 34.00 ? 609 ALA B CB 1 ATOM 10534 N N . ALA B 1 574 ? 88.510 63.098 65.728 1.00 32.40 ? 610 ALA B N 1 ATOM 10535 C CA . ALA B 1 574 ? 88.594 61.753 65.184 1.00 36.28 ? 610 ALA B CA 1 ATOM 10536 C C . ALA B 1 574 ? 90.020 61.449 64.729 1.00 36.85 ? 610 ALA B C 1 ATOM 10537 O O . ALA B 1 574 ? 90.536 60.362 64.982 1.00 41.96 ? 610 ALA B O 1 ATOM 10538 C CB . ALA B 1 574 ? 87.601 61.574 64.032 1.00 33.63 ? 610 ALA B CB 1 ATOM 10539 N N . ARG B 1 575 ? 90.656 62.413 64.069 1.00 35.28 ? 611 ARG B N 1 ATOM 10540 C CA . ARG B 1 575 ? 92.046 62.257 63.638 1.00 41.45 ? 611 ARG B CA 1 ATOM 10541 C C . ARG B 1 575 ? 92.950 61.922 64.810 1.00 44.29 ? 611 ARG B C 1 ATOM 10542 O O . ARG B 1 575 ? 93.813 61.049 64.708 1.00 48.51 ? 611 ARG B O 1 ATOM 10543 C CB . ARG B 1 575 ? 92.568 63.533 62.968 1.00 39.65 ? 611 ARG B CB 1 ATOM 10544 C CG . ARG B 1 575 ? 92.126 63.737 61.543 1.00 43.55 ? 611 ARG B CG 1 ATOM 10545 C CD . ARG B 1 575 ? 92.851 64.931 60.907 1.00 43.56 ? 611 ARG B CD 1 ATOM 10546 N NE . ARG B 1 575 ? 92.152 65.433 59.722 1.00 42.72 ? 611 ARG B NE 1 ATOM 10547 C CZ . ARG B 1 575 ? 92.246 64.884 58.515 1.00 55.03 ? 611 ARG B CZ 1 ATOM 10548 N NH1 . ARG B 1 575 ? 93.008 63.804 58.330 1.00 53.06 ? 611 ARG B NH1 1 ATOM 10549 N NH2 . ARG B 1 575 ? 91.575 65.406 57.489 1.00 55.63 ? 611 ARG B NH2 1 ATOM 10550 N N . GLN B 1 576 ? 92.756 62.629 65.919 1.00 41.02 ? 612 GLN B N 1 ATOM 10551 C CA . GLN B 1 576 ? 93.599 62.438 67.090 1.00 44.23 ? 612 GLN B CA 1 ATOM 10552 C C . GLN B 1 576 ? 93.319 61.085 67.718 1.00 47.04 ? 612 GLN B C 1 ATOM 10553 O O . GLN B 1 576 ? 94.247 60.370 68.096 1.00 50.90 ? 612 GLN B O 1 ATOM 10554 C CB . GLN B 1 576 ? 93.384 63.558 68.104 1.00 41.50 ? 612 GLN B CB 1 ATOM 10555 C CG . GLN B 1 576 ? 93.603 64.937 67.531 1.00 47.56 ? 612 GLN B CG 1 ATOM 10556 C CD . GLN B 1 576 ? 94.555 65.787 68.362 1.00 55.41 ? 612 GLN B CD 1 ATOM 10557 O OE1 . GLN B 1 576 ? 95.181 66.711 67.842 1.00 63.08 ? 612 GLN B OE1 1 ATOM 10558 N NE2 . GLN B 1 576 ? 94.668 65.479 69.655 1.00 50.46 ? 612 GLN B NE2 1 ATOM 10559 N N . PHE B 1 577 ? 92.041 60.727 67.822 1.00 42.73 ? 613 PHE B N 1 ATOM 10560 C CA . PHE B 1 577 ? 91.674 59.395 68.304 1.00 47.81 ? 613 PHE B CA 1 ATOM 10561 C C . PHE B 1 577 ? 92.345 58.300 67.446 1.00 47.34 ? 613 PHE B C 1 ATOM 10562 O O . PHE B 1 577 ? 92.760 57.268 67.971 1.00 48.74 ? 613 PHE B O 1 ATOM 10563 C CB . PHE B 1 577 ? 90.147 59.194 68.311 1.00 40.53 ? 613 PHE B CB 1 ATOM 10564 C CG . PHE B 1 577 ? 89.392 60.142 69.218 1.00 40.07 ? 613 PHE B CG 1 ATOM 10565 C CD1 . PHE B 1 577 ? 89.999 60.708 70.330 1.00 42.24 ? 613 PHE B CD1 1 ATOM 10566 C CD2 . PHE B 1 577 ? 88.066 60.465 68.947 1.00 35.86 ? 613 PHE B CD2 1 ATOM 10567 C CE1 . PHE B 1 577 ? 89.290 61.575 71.162 1.00 40.86 ? 613 PHE B CE1 1 ATOM 10568 C CE2 . PHE B 1 577 ? 87.352 61.327 69.769 1.00 36.72 ? 613 PHE B CE2 1 ATOM 10569 C CZ . PHE B 1 577 ? 87.969 61.887 70.881 1.00 35.00 ? 613 PHE B CZ 1 ATOM 10570 N N . SER B 1 578 ? 92.443 58.534 66.135 1.00 46.39 ? 614 SER B N 1 ATOM 10571 C CA . SER B 1 578 ? 93.066 57.582 65.199 1.00 50.61 ? 614 SER B CA 1 ATOM 10572 C C . SER B 1 578 ? 94.554 57.376 65.458 1.00 54.32 ? 614 SER B C 1 ATOM 10573 O O . SER B 1 578 ? 95.092 56.293 65.206 1.00 60.18 ? 614 SER B O 1 ATOM 10574 C CB . SER B 1 578 ? 92.906 58.055 63.755 1.00 51.17 ? 614 SER B CB 1 ATOM 10575 O OG . SER B 1 578 ? 91.555 58.310 63.448 1.00 56.44 ? 614 SER B OG 1 ATOM 10576 N N . LYS B 1 579 ? 95.219 58.433 65.917 1.00 54.49 ? 615 LYS B N 1 ATOM 10577 C CA . LYS B 1 579 ? 96.621 58.358 66.296 1.00 56.74 ? 615 LYS B CA 1 ATOM 10578 C C . LYS B 1 579 ? 96.780 57.374 67.444 1.00 56.63 ? 615 LYS B C 1 ATOM 10579 O O . LYS B 1 579 ? 97.677 56.532 67.439 1.00 61.37 ? 615 LYS B O 1 ATOM 10580 C CB . LYS B 1 579 ? 97.146 59.731 66.727 1.00 57.85 ? 615 LYS B CB 1 ATOM 10581 C CG . LYS B 1 579 ? 97.320 60.748 65.597 1.00 61.63 ? 615 LYS B CG 1 ATOM 10582 C CD . LYS B 1 579 ? 97.798 62.090 66.172 1.00 66.24 ? 615 LYS B CD 1 ATOM 10583 C CE . LYS B 1 579 ? 97.815 63.205 65.121 1.00 70.52 ? 615 LYS B CE 1 ATOM 10584 N NZ . LYS B 1 579 ? 96.449 63.613 64.662 1.00 62.00 ? 615 LYS B NZ 1 ATOM 10585 N N . MET B 1 580 ? 95.909 57.491 68.437 1.00 55.37 ? 616 MET B N 1 ATOM 10586 C CA . MET B 1 580 ? 95.949 56.589 69.575 1.00 56.43 ? 616 MET B CA 1 ATOM 10587 C C . MET B 1 580 ? 96.102 55.154 69.062 1.00 56.38 ? 616 MET B C 1 ATOM 10588 O O . MET B 1 580 ? 95.511 54.770 68.045 1.00 58.16 ? 616 MET B O 1 ATOM 10589 C CB . MET B 1 580 ? 94.707 56.778 70.457 1.00 54.50 ? 616 MET B CB 1 ATOM 10590 C CG . MET B 1 580 ? 94.694 58.118 71.211 1.00 52.91 ? 616 MET B CG 1 ATOM 10591 S SD . MET B 1 580 ? 93.108 58.539 71.977 1.00 62.95 ? 616 MET B SD 1 ATOM 10592 C CE . MET B 1 580 ? 93.632 59.487 73.413 1.00 61.03 ? 616 MET B CE 1 ATOM 10593 N N . GLY B 1 581 ? 96.925 54.375 69.751 1.00 54.94 ? 617 GLY B N 1 ATOM 10594 C CA . GLY B 1 581 ? 97.357 53.095 69.227 1.00 55.12 ? 617 GLY B CA 1 ATOM 10595 C C . GLY B 1 581 ? 96.352 51.985 69.420 1.00 54.08 ? 617 GLY B C 1 ATOM 10596 O O . GLY B 1 581 ? 96.654 50.819 69.154 1.00 55.90 ? 617 GLY B O 1 ATOM 10597 N N . PHE B 1 582 ? 95.159 52.340 69.888 1.00 49.97 ? 618 PHE B N 1 ATOM 10598 C CA . PHE B 1 582 ? 94.123 51.341 70.128 1.00 46.92 ? 618 PHE B CA 1 ATOM 10599 C C . PHE B 1 582 ? 92.899 51.550 69.245 1.00 45.32 ? 618 PHE B C 1 ATOM 10600 O O . PHE B 1 582 ? 91.894 50.868 69.408 1.00 42.14 ? 618 PHE B O 1 ATOM 10601 C CB . PHE B 1 582 ? 93.723 51.290 71.605 1.00 45.94 ? 618 PHE B CB 1 ATOM 10602 C CG . PHE B 1 582 ? 93.339 52.626 72.184 1.00 47.80 ? 618 PHE B CG 1 ATOM 10603 C CD1 . PHE B 1 582 ? 92.068 53.141 71.998 1.00 46.38 ? 618 PHE B CD1 1 ATOM 10604 C CD2 . PHE B 1 582 ? 94.247 53.360 72.929 1.00 49.22 ? 618 PHE B CD2 1 ATOM 10605 C CE1 . PHE B 1 582 ? 91.716 54.365 72.539 1.00 46.10 ? 618 PHE B CE1 1 ATOM 10606 C CE2 . PHE B 1 582 ? 93.900 54.584 73.467 1.00 47.61 ? 618 PHE B CE2 1 ATOM 10607 C CZ . PHE B 1 582 ? 92.634 55.086 73.277 1.00 44.60 ? 618 PHE B CZ 1 ATOM 10608 N N . VAL B 1 583 ? 92.998 52.484 68.303 1.00 42.88 ? 619 VAL B N 1 ATOM 10609 C CA . VAL B 1 583 ? 91.912 52.734 67.373 1.00 39.31 ? 619 VAL B CA 1 ATOM 10610 C C . VAL B 1 583 ? 92.277 52.292 65.964 1.00 40.80 ? 619 VAL B C 1 ATOM 10611 O O . VAL B 1 583 ? 93.297 52.699 65.412 1.00 45.02 ? 619 VAL B O 1 ATOM 10612 C CB . VAL B 1 583 ? 91.542 54.222 67.321 1.00 40.14 ? 619 VAL B CB 1 ATOM 10613 C CG1 . VAL B 1 583 ? 90.513 54.468 66.226 1.00 42.59 ? 619 VAL B CG1 1 ATOM 10614 C CG2 . VAL B 1 583 ? 91.016 54.679 68.649 1.00 40.44 ? 619 VAL B CG2 1 ATOM 10615 N N . ASP B 1 584 ? 91.422 51.462 65.380 1.00 44.62 ? 620 ASP B N 1 ATOM 10616 C CA . ASP B 1 584 ? 91.568 51.046 63.988 1.00 38.52 ? 620 ASP B CA 1 ATOM 10617 C C . ASP B 1 584 ? 91.123 52.171 63.070 1.00 40.22 ? 620 ASP B C 1 ATOM 10618 O O . ASP B 1 584 ? 89.924 52.424 62.927 1.00 39.57 ? 620 ASP B O 1 ATOM 10619 C CB . ASP B 1 584 ? 90.699 49.816 63.739 1.00 38.48 ? 620 ASP B CB 1 ATOM 10620 C CG . ASP B 1 584 ? 90.850 49.263 62.342 1.00 43.83 ? 620 ASP B CG 1 ATOM 10621 O OD1 . ASP B 1 584 ? 91.418 49.962 61.461 1.00 43.05 ? 620 ASP B OD1 1 ATOM 10622 O OD2 . ASP B 1 584 ? 90.388 48.120 62.134 1.00 44.54 ? 620 ASP B OD2 1 ATOM 10623 N N . ASN B 1 585 ? 92.078 52.836 62.426 1.00 41.56 ? 621 ASN B N 1 ATOM 10624 C CA . ASN B 1 585 ? 91.747 53.978 61.586 1.00 40.26 ? 621 ASN B CA 1 ATOM 10625 C C . ASN B 1 585 ? 91.012 53.621 60.292 1.00 44.57 ? 621 ASN B C 1 ATOM 10626 O O . ASN B 1 585 ? 90.555 54.507 59.571 1.00 44.56 ? 621 ASN B O 1 ATOM 10627 C CB . ASN B 1 585 ? 92.983 54.831 61.299 1.00 44.60 ? 621 ASN B CB 1 ATOM 10628 C CG . ASN B 1 585 ? 93.987 54.127 60.415 1.00 52.94 ? 621 ASN B CG 1 ATOM 10629 O OD1 . ASN B 1 585 ? 94.196 52.916 60.529 1.00 55.54 ? 621 ASN B OD1 1 ATOM 10630 N ND2 . ASN B 1 585 ? 94.616 54.883 59.520 1.00 54.39 ? 621 ASN B ND2 1 ATOM 10631 N N . LYS B 1 586 ? 90.885 52.330 60.002 1.00 40.34 ? 622 LYS B N 1 ATOM 10632 C CA . LYS B 1 586 ? 90.110 51.904 58.842 1.00 44.78 ? 622 LYS B CA 1 ATOM 10633 C C . LYS B 1 586 ? 88.630 51.733 59.200 1.00 41.21 ? 622 LYS B C 1 ATOM 10634 O O . LYS B 1 586 ? 87.770 51.581 58.327 1.00 37.57 ? 622 LYS B O 1 ATOM 10635 C CB . LYS B 1 586 ? 90.695 50.618 58.259 1.00 43.11 ? 622 LYS B CB 1 ATOM 10636 C CG . LYS B 1 586 ? 91.956 50.865 57.426 1.00 53.58 ? 622 LYS B CG 1 ATOM 10637 C CD . LYS B 1 586 ? 92.744 49.582 57.183 1.00 60.13 ? 622 LYS B CD 1 ATOM 10638 C CE . LYS B 1 586 ? 93.389 49.073 58.473 1.00 61.66 ? 622 LYS B CE 1 ATOM 10639 N NZ . LYS B 1 586 ? 93.024 47.646 58.763 1.00 59.01 ? 622 LYS B NZ 1 ATOM 10640 N N . ARG B 1 587 ? 88.334 51.780 60.492 1.00 39.34 ? 623 ARG B N 1 ATOM 10641 C CA . ARG B 1 587 ? 86.964 51.596 60.948 1.00 35.97 ? 623 ARG B CA 1 ATOM 10642 C C . ARG B 1 587 ? 86.502 52.681 61.913 1.00 35.61 ? 623 ARG B C 1 ATOM 10643 O O . ARG B 1 587 ? 86.287 52.425 63.090 1.00 34.11 ? 623 ARG B O 1 ATOM 10644 C CB . ARG B 1 587 ? 86.802 50.209 61.568 1.00 33.41 ? 623 ARG B CB 1 ATOM 10645 C CG . ARG B 1 587 ? 86.969 49.077 60.552 1.00 36.08 ? 623 ARG B CG 1 ATOM 10646 C CD . ARG B 1 587 ? 86.641 47.734 61.177 1.00 35.77 ? 623 ARG B CD 1 ATOM 10647 N NE . ARG B 1 587 ? 87.628 47.349 62.177 1.00 32.14 ? 623 ARG B NE 1 ATOM 10648 C CZ . ARG B 1 587 ? 87.434 46.412 63.101 1.00 35.92 ? 623 ARG B CZ 1 ATOM 10649 N NH1 . ARG B 1 587 ? 86.279 45.774 63.175 1.00 37.15 ? 623 ARG B NH1 1 ATOM 10650 N NH2 . ARG B 1 587 ? 88.389 46.126 63.971 1.00 38.46 ? 623 ARG B NH2 1 ATOM 10651 N N . ILE B 1 588 ? 86.339 53.892 61.397 1.00 35.49 ? 624 ILE B N 1 ATOM 10652 C CA . ILE B 1 588 ? 85.776 54.985 62.175 1.00 33.18 ? 624 ILE B CA 1 ATOM 10653 C C . ILE B 1 588 ? 84.422 55.376 61.597 1.00 34.49 ? 624 ILE B C 1 ATOM 10654 O O . ILE B 1 588 ? 84.321 55.733 60.429 1.00 35.79 ? 624 ILE B O 1 ATOM 10655 C CB . ILE B 1 588 ? 86.707 56.211 62.152 1.00 34.76 ? 624 ILE B CB 1 ATOM 10656 C CG1 . ILE B 1 588 ? 88.043 55.861 62.791 1.00 34.80 ? 624 ILE B CG1 1 ATOM 10657 C CG2 . ILE B 1 588 ? 86.091 57.391 62.893 1.00 30.00 ? 624 ILE B CG2 1 ATOM 10658 C CD1 . ILE B 1 588 ? 89.031 56.978 62.695 1.00 43.53 ? 624 ILE B CD1 1 ATOM 10659 N N . ALA B 1 589 ? 83.377 55.300 62.413 1.00 32.20 ? 625 ALA B N 1 ATOM 10660 C CA . ALA B 1 589 ? 82.054 55.741 61.988 1.00 30.05 ? 625 ALA B CA 1 ATOM 10661 C C . ALA B 1 589 ? 81.624 57.002 62.741 1.00 31.32 ? 625 ALA B C 1 ATOM 10662 O O . ALA B 1 589 ? 82.243 57.400 63.733 1.00 29.18 ? 625 ALA B O 1 ATOM 10663 C CB . ALA B 1 589 ? 81.039 54.632 62.207 1.00 31.56 ? 625 ALA B CB 1 ATOM 10664 N N . ILE B 1 590 ? 80.555 57.624 62.277 1.00 27.51 ? 626 ILE B N 1 ATOM 10665 C CA . ILE B 1 590 ? 80.006 58.774 62.970 1.00 27.74 ? 626 ILE B CA 1 ATOM 10666 C C . ILE B 1 590 ? 78.484 58.715 62.934 1.00 30.19 ? 626 ILE B C 1 ATOM 10667 O O . ILE B 1 590 ? 77.902 58.237 61.969 1.00 28.37 ? 626 ILE B O 1 ATOM 10668 C CB . ILE B 1 590 ? 80.490 60.082 62.330 1.00 27.70 ? 626 ILE B CB 1 ATOM 10669 C CG1 . ILE B 1 590 ? 80.047 61.283 63.162 1.00 27.90 ? 626 ILE B CG1 1 ATOM 10670 C CG2 . ILE B 1 590 ? 79.980 60.204 60.910 1.00 29.42 ? 626 ILE B CG2 1 ATOM 10671 C CD1 . ILE B 1 590 ? 80.609 62.605 62.674 1.00 28.73 ? 626 ILE B CD1 1 ATOM 10672 N N . TRP B 1 591 ? 77.833 59.189 63.990 1.00 28.39 ? 627 TRP B N 1 ATOM 10673 C CA . TRP B 1 591 ? 76.381 59.278 63.968 1.00 28.88 ? 627 TRP B CA 1 ATOM 10674 C C . TRP B 1 591 ? 75.868 60.371 64.893 1.00 29.60 ? 627 TRP B C 1 ATOM 10675 O O . TRP B 1 591 ? 76.526 60.743 65.868 1.00 27.33 ? 627 TRP B O 1 ATOM 10676 C CB . TRP B 1 591 ? 75.756 57.930 64.316 1.00 30.53 ? 627 TRP B CB 1 ATOM 10677 C CG . TRP B 1 591 ? 75.374 57.767 65.756 1.00 28.13 ? 627 TRP B CG 1 ATOM 10678 C CD1 . TRP B 1 591 ? 76.201 57.464 66.802 1.00 29.87 ? 627 TRP B CD1 1 ATOM 10679 C CD2 . TRP B 1 591 ? 74.052 57.864 66.305 1.00 26.73 ? 627 TRP B CD2 1 ATOM 10680 N NE1 . TRP B 1 591 ? 75.471 57.373 67.969 1.00 28.15 ? 627 TRP B NE1 1 ATOM 10681 C CE2 . TRP B 1 591 ? 74.152 57.616 67.689 1.00 29.59 ? 627 TRP B CE2 1 ATOM 10682 C CE3 . TRP B 1 591 ? 72.793 58.133 65.758 1.00 30.07 ? 627 TRP B CE3 1 ATOM 10683 C CZ2 . TRP B 1 591 ? 73.044 57.639 68.534 1.00 31.75 ? 627 TRP B CZ2 1 ATOM 10684 C CZ3 . TRP B 1 591 ? 71.692 58.151 66.600 1.00 30.00 ? 627 TRP B CZ3 1 ATOM 10685 C CH2 . TRP B 1 591 ? 71.826 57.908 67.972 1.00 29.50 ? 627 TRP B CH2 1 ATOM 10686 N N . GLY B 1 592 ? 74.692 60.893 64.572 1.00 28.40 ? 628 GLY B N 1 ATOM 10687 C CA . GLY B 1 592 ? 74.054 61.880 65.423 1.00 27.56 ? 628 GLY B CA 1 ATOM 10688 C C . GLY B 1 592 ? 72.591 62.038 65.094 1.00 27.59 ? 628 GLY B C 1 ATOM 10689 O O . GLY B 1 592 ? 72.132 61.621 64.031 1.00 30.68 ? 628 GLY B O 1 ATOM 10690 N N . TRP B 1 593 ? 71.866 62.667 66.005 1.00 28.28 ? 629 TRP B N 1 ATOM 10691 C CA . TRP B 1 593 ? 70.437 62.875 65.875 1.00 27.39 ? 629 TRP B CA 1 ATOM 10692 C C . TRP B 1 593 ? 70.191 64.375 65.942 1.00 28.13 ? 629 TRP B C 1 ATOM 10693 O O . TRP B 1 593 ? 70.837 65.077 66.722 1.00 30.50 ? 629 TRP B O 1 ATOM 10694 C CB . TRP B 1 593 ? 69.755 62.217 67.074 1.00 28.05 ? 629 TRP B CB 1 ATOM 10695 C CG . TRP B 1 593 ? 68.299 61.920 66.917 1.00 26.00 ? 629 TRP B CG 1 ATOM 10696 C CD1 . TRP B 1 593 ? 67.309 62.795 66.583 1.00 26.35 ? 629 TRP B CD1 1 ATOM 10697 C CD2 . TRP B 1 593 ? 67.660 60.655 67.146 1.00 25.02 ? 629 TRP B CD2 1 ATOM 10698 N NE1 . TRP B 1 593 ? 66.093 62.149 66.586 1.00 26.14 ? 629 TRP B NE1 1 ATOM 10699 C CE2 . TRP B 1 593 ? 66.288 60.832 66.919 1.00 24.27 ? 629 TRP B CE2 1 ATOM 10700 C CE3 . TRP B 1 593 ? 68.123 59.387 67.517 1.00 26.90 ? 629 TRP B CE3 1 ATOM 10701 C CZ2 . TRP B 1 593 ? 65.369 59.788 67.045 1.00 26.60 ? 629 TRP B CZ2 1 ATOM 10702 C CZ3 . TRP B 1 593 ? 67.204 58.351 67.636 1.00 28.39 ? 629 TRP B CZ3 1 ATOM 10703 C CH2 . TRP B 1 593 ? 65.845 58.564 67.412 1.00 24.07 ? 629 TRP B CH2 1 ATOM 10704 N N . SER B 1 594 ? 69.265 64.878 65.143 1.00 26.06 ? 630 SER B N 1 ATOM 10705 C CA . SER B 1 594 ? 68.882 66.280 65.263 1.00 28.24 ? 630 SER B CA 1 ATOM 10706 C C . SER B 1 594 ? 70.038 67.221 64.901 1.00 30.08 ? 630 SER B C 1 ATOM 10707 O O . SER B 1 594 ? 70.556 67.152 63.791 1.00 28.63 ? 630 SER B O 1 ATOM 10708 C CB . SER B 1 594 ? 68.382 66.539 66.681 1.00 28.81 ? 630 SER B CB 1 ATOM 10709 O OG . SER B 1 594 ? 67.776 67.798 66.739 1.00 35.84 ? 630 SER B OG 1 ATOM 10710 N N . TYR B 1 595 ? 70.457 68.114 65.795 1.00 29.11 ? 631 TYR B N 1 ATOM 10711 C CA . TYR B 1 595 ? 71.645 68.900 65.451 1.00 27.20 ? 631 TYR B CA 1 ATOM 10712 C C . TYR B 1 595 ? 72.795 67.939 65.122 1.00 25.85 ? 631 TYR B C 1 ATOM 10713 O O . TYR B 1 595 ? 73.606 68.205 64.242 1.00 25.68 ? 631 TYR B O 1 ATOM 10714 C CB . TYR B 1 595 ? 72.052 69.882 66.556 1.00 26.25 ? 631 TYR B CB 1 ATOM 10715 C CG . TYR B 1 595 ? 73.001 70.967 66.078 1.00 24.05 ? 631 TYR B CG 1 ATOM 10716 C CD1 . TYR B 1 595 ? 74.347 70.698 65.870 1.00 24.52 ? 631 TYR B CD1 1 ATOM 10717 C CD2 . TYR B 1 595 ? 72.551 72.259 65.831 1.00 23.38 ? 631 TYR B CD2 1 ATOM 10718 C CE1 . TYR B 1 595 ? 75.222 71.683 65.418 1.00 24.56 ? 631 TYR B CE1 1 ATOM 10719 C CE2 . TYR B 1 595 ? 73.418 73.253 65.390 1.00 23.59 ? 631 TYR B CE2 1 ATOM 10720 C CZ . TYR B 1 595 ? 74.755 72.956 65.187 1.00 26.98 ? 631 TYR B CZ 1 ATOM 10721 O OH . TYR B 1 595 ? 75.635 73.930 64.747 1.00 28.29 ? 631 TYR B OH 1 ATOM 10722 N N . GLY B 1 596 ? 72.859 66.816 65.830 1.00 25.94 ? 632 GLY B N 1 ATOM 10723 C CA . GLY B 1 596 ? 73.892 65.821 65.575 1.00 25.01 ? 632 GLY B CA 1 ATOM 10724 C C . GLY B 1 596 ? 73.759 65.143 64.218 1.00 28.80 ? 632 GLY B C 1 ATOM 10725 O O . GLY B 1 596 ? 74.726 64.600 63.678 1.00 28.23 ? 632 GLY B O 1 ATOM 10726 N N . GLY B 1 597 ? 72.556 65.151 63.662 1.00 25.45 ? 633 GLY B N 1 ATOM 10727 C CA . GLY B 1 597 ? 72.372 64.618 62.324 1.00 26.22 ? 633 GLY B CA 1 ATOM 10728 C C . GLY B 1 597 ? 72.960 65.569 61.297 1.00 26.21 ? 633 GLY B C 1 ATOM 10729 O O . GLY B 1 597 ? 73.628 65.153 60.359 1.00 26.17 ? 633 GLY B O 1 ATOM 10730 N N . TYR B 1 598 ? 72.701 66.859 61.474 1.00 27.29 ? 634 TYR B N 1 ATOM 10731 C CA . TYR B 1 598 ? 73.289 67.890 60.626 1.00 24.08 ? 634 TYR B CA 1 ATOM 10732 C C . TYR B 1 598 ? 74.822 67.813 60.647 1.00 25.88 ? 634 TYR B C 1 ATOM 10733 O O . TYR B 1 598 ? 75.469 67.715 59.606 1.00 26.22 ? 634 TYR B O 1 ATOM 10734 C CB . TYR B 1 598 ? 72.805 69.253 61.104 1.00 26.73 ? 634 TYR B CB 1 ATOM 10735 C CG . TYR B 1 598 ? 73.505 70.442 60.472 1.00 28.33 ? 634 TYR B CG 1 ATOM 10736 C CD1 . TYR B 1 598 ? 73.257 70.807 59.159 1.00 24.75 ? 634 TYR B CD1 1 ATOM 10737 C CD2 . TYR B 1 598 ? 74.406 71.208 61.213 1.00 25.32 ? 634 TYR B CD2 1 ATOM 10738 C CE1 . TYR B 1 598 ? 73.898 71.905 58.595 1.00 27.35 ? 634 TYR B CE1 1 ATOM 10739 C CE2 . TYR B 1 598 ? 75.046 72.296 60.668 1.00 26.50 ? 634 TYR B CE2 1 ATOM 10740 C CZ . TYR B 1 598 ? 74.796 72.646 59.372 1.00 25.26 ? 634 TYR B CZ 1 ATOM 10741 O OH . TYR B 1 598 ? 75.446 73.738 58.857 1.00 28.25 ? 634 TYR B OH 1 ATOM 10742 N N . VAL B 1 599 ? 75.410 67.828 61.834 1.00 27.48 ? 635 VAL B N 1 ATOM 10743 C CA . VAL B 1 599 ? 76.866 67.781 61.938 1.00 26.88 ? 635 VAL B CA 1 ATOM 10744 C C . VAL B 1 599 ? 77.426 66.496 61.287 1.00 26.95 ? 635 VAL B C 1 ATOM 10745 O O . VAL B 1 599 ? 78.403 66.545 60.536 1.00 26.83 ? 635 VAL B O 1 ATOM 10746 C CB . VAL B 1 599 ? 77.340 67.908 63.407 1.00 27.41 ? 635 VAL B CB 1 ATOM 10747 C CG1 . VAL B 1 599 ? 78.824 67.643 63.510 1.00 27.41 ? 635 VAL B CG1 1 ATOM 10748 C CG2 . VAL B 1 599 ? 77.000 69.284 63.969 1.00 22.33 ? 635 VAL B CG2 1 ATOM 10749 N N . THR B 1 600 ? 76.810 65.354 61.573 1.00 25.28 ? 636 THR B N 1 ATOM 10750 C CA . THR B 1 600 ? 77.227 64.095 60.961 1.00 28.88 ? 636 THR B CA 1 ATOM 10751 C C . THR B 1 600 ? 77.226 64.197 59.435 1.00 26.96 ? 636 THR B C 1 ATOM 10752 O O . THR B 1 600 ? 78.145 63.718 58.763 1.00 33.48 ? 636 THR B O 1 ATOM 10753 C CB . THR B 1 600 ? 76.311 62.938 61.384 1.00 28.04 ? 636 THR B CB 1 ATOM 10754 O OG1 . THR B 1 600 ? 76.486 62.683 62.773 1.00 29.23 ? 636 THR B OG1 1 ATOM 10755 C CG2 . THR B 1 600 ? 76.638 61.657 60.609 1.00 29.60 ? 636 THR B CG2 1 ATOM 10756 N N . SER B 1 601 ? 76.187 64.820 58.890 1.00 28.74 ? 637 SER B N 1 ATOM 10757 C CA . SER B 1 601 ? 76.030 64.939 57.448 1.00 27.74 ? 637 SER B CA 1 ATOM 10758 C C . SER B 1 601 ? 77.105 65.842 56.863 1.00 32.06 ? 637 SER B C 1 ATOM 10759 O O . SER B 1 601 ? 77.695 65.535 55.818 1.00 29.66 ? 637 SER B O 1 ATOM 10760 C CB . SER B 1 601 ? 74.644 65.485 57.097 1.00 29.67 ? 637 SER B CB 1 ATOM 10761 O OG . SER B 1 601 ? 73.633 64.549 57.439 1.00 25.90 ? 637 SER B OG 1 ATOM 10762 N N . MET B 1 602 ? 77.355 66.962 57.535 1.00 28.28 ? 638 MET B N 1 ATOM 10763 C CA . MET B 1 602 ? 78.387 67.899 57.097 1.00 28.94 ? 638 MET B CA 1 ATOM 10764 C C . MET B 1 602 ? 79.777 67.277 57.168 1.00 29.75 ? 638 MET B C 1 ATOM 10765 O O . MET B 1 602 ? 80.600 67.486 56.279 1.00 33.55 ? 638 MET B O 1 ATOM 10766 C CB . MET B 1 602 ? 78.324 69.179 57.926 1.00 27.31 ? 638 MET B CB 1 ATOM 10767 C CG . MET B 1 602 ? 77.007 69.894 57.793 1.00 26.13 ? 638 MET B CG 1 ATOM 10768 S SD . MET B 1 602 ? 76.903 70.760 56.231 1.00 32.01 ? 638 MET B SD 1 ATOM 10769 C CE . MET B 1 602 ? 77.909 72.205 56.568 1.00 35.31 ? 638 MET B CE 1 ATOM 10770 N N . VAL B 1 603 ? 80.035 66.511 58.228 1.00 30.15 ? 639 VAL B N 1 ATOM 10771 C CA . VAL B 1 603 ? 81.292 65.782 58.367 1.00 27.86 ? 639 VAL B CA 1 ATOM 10772 C C . VAL B 1 603 ? 81.480 64.749 57.248 1.00 32.57 ? 639 VAL B C 1 ATOM 10773 O O . VAL B 1 603 ? 82.556 64.671 56.643 1.00 31.05 ? 639 VAL B O 1 ATOM 10774 C CB . VAL B 1 603 ? 81.388 65.055 59.721 1.00 30.02 ? 639 VAL B CB 1 ATOM 10775 C CG1 . VAL B 1 603 ? 82.530 64.051 59.694 1.00 31.02 ? 639 VAL B CG1 1 ATOM 10776 C CG2 . VAL B 1 603 ? 81.593 66.064 60.848 1.00 29.20 ? 639 VAL B CG2 1 ATOM 10777 N N . LEU B 1 604 ? 80.436 63.965 56.978 1.00 30.98 ? 640 LEU B N 1 ATOM 10778 C CA . LEU B 1 604 ? 80.496 62.936 55.938 1.00 32.09 ? 640 LEU B CA 1 ATOM 10779 C C . LEU B 1 604 ? 80.637 63.554 54.554 1.00 30.71 ? 640 LEU B C 1 ATOM 10780 O O . LEU B 1 604 ? 81.176 62.931 53.639 1.00 35.36 ? 640 LEU B O 1 ATOM 10781 C CB . LEU B 1 604 ? 79.252 62.056 55.984 1.00 28.56 ? 640 LEU B CB 1 ATOM 10782 C CG . LEU B 1 604 ? 79.103 61.140 57.190 1.00 31.63 ? 640 LEU B CG 1 ATOM 10783 C CD1 . LEU B 1 604 ? 77.805 60.351 57.089 1.00 28.94 ? 640 LEU B CD1 1 ATOM 10784 C CD2 . LEU B 1 604 ? 80.286 60.212 57.269 1.00 31.35 ? 640 LEU B CD2 1 ATOM 10785 N N . GLY B 1 605 ? 80.150 64.784 54.415 1.00 32.60 ? 641 GLY B N 1 ATOM 10786 C CA . GLY B 1 605 ? 80.218 65.522 53.168 1.00 30.98 ? 641 GLY B CA 1 ATOM 10787 C C . GLY B 1 605 ? 81.446 66.408 53.054 1.00 33.42 ? 641 GLY B C 1 ATOM 10788 O O . GLY B 1 605 ? 81.549 67.212 52.127 1.00 35.22 ? 641 GLY B O 1 ATOM 10789 N N . SER B 1 606 ? 82.383 66.259 53.988 1.00 31.40 ? 642 SER B N 1 ATOM 10790 C CA . SER B 1 606 ? 83.562 67.120 54.031 1.00 31.08 ? 642 SER B CA 1 ATOM 10791 C C . SER B 1 606 ? 84.695 66.611 53.140 1.00 35.89 ? 642 SER B C 1 ATOM 10792 O O . SER B 1 606 ? 85.585 67.379 52.775 1.00 35.57 ? 642 SER B O 1 ATOM 10793 C CB . SER B 1 606 ? 84.084 67.261 55.465 1.00 29.09 ? 642 SER B CB 1 ATOM 10794 O OG . SER B 1 606 ? 84.644 66.030 55.914 1.00 29.81 ? 642 SER B OG 1 ATOM 10795 N N . GLY B 1 607 ? 84.675 65.323 52.802 1.00 36.77 ? 643 GLY B N 1 ATOM 10796 C CA . GLY B 1 607 ? 85.722 64.759 51.965 1.00 35.98 ? 643 GLY B CA 1 ATOM 10797 C C . GLY B 1 607 ? 87.001 64.532 52.754 1.00 40.16 ? 643 GLY B C 1 ATOM 10798 O O . GLY B 1 607 ? 88.061 64.305 52.183 1.00 43.32 ? 643 GLY B O 1 ATOM 10799 N N . SER B 1 608 ? 86.895 64.573 54.077 1.00 33.18 ? 644 SER B N 1 ATOM 10800 C CA . SER B 1 608 ? 88.059 64.457 54.951 1.00 35.94 ? 644 SER B CA 1 ATOM 10801 C C . SER B 1 608 ? 88.715 63.076 54.857 1.00 39.01 ? 644 SER B C 1 ATOM 10802 O O . SER B 1 608 ? 89.891 62.912 55.184 1.00 37.09 ? 644 SER B O 1 ATOM 10803 C CB . SER B 1 608 ? 87.661 64.735 56.405 1.00 30.88 ? 644 SER B CB 1 ATOM 10804 O OG . SER B 1 608 ? 87.168 63.553 57.023 1.00 33.36 ? 644 SER B OG 1 ATOM 10805 N N . GLY B 1 609 ? 87.951 62.082 54.422 1.00 35.10 ? 645 GLY B N 1 ATOM 10806 C CA . GLY B 1 609 ? 88.471 60.737 54.288 1.00 35.39 ? 645 GLY B CA 1 ATOM 10807 C C . GLY B 1 609 ? 88.663 60.019 55.607 1.00 37.62 ? 645 GLY B C 1 ATOM 10808 O O . GLY B 1 609 ? 89.086 58.864 55.631 1.00 39.46 ? 645 GLY B O 1 ATOM 10809 N N . VAL B 1 610 ? 88.341 60.688 56.711 1.00 38.69 ? 646 VAL B N 1 ATOM 10810 C CA . VAL B 1 610 ? 88.510 60.093 58.035 1.00 33.67 ? 646 VAL B CA 1 ATOM 10811 C C . VAL B 1 610 ? 87.461 59.024 58.369 1.00 35.76 ? 646 VAL B C 1 ATOM 10812 O O . VAL B 1 610 ? 87.757 58.049 59.063 1.00 34.47 ? 646 VAL B O 1 ATOM 10813 C CB . VAL B 1 610 ? 88.504 61.177 59.137 1.00 37.72 ? 646 VAL B CB 1 ATOM 10814 C CG1 . VAL B 1 610 ? 88.618 60.546 60.505 1.00 34.42 ? 646 VAL B CG1 1 ATOM 10815 C CG2 . VAL B 1 610 ? 89.641 62.170 58.912 1.00 38.44 ? 646 VAL B CG2 1 ATOM 10816 N N . PHE B 1 611 ? 86.237 59.205 57.877 1.00 33.27 ? 647 PHE B N 1 ATOM 10817 C CA . PHE B 1 611 ? 85.131 58.326 58.247 1.00 31.51 ? 647 PHE B CA 1 ATOM 10818 C C . PHE B 1 611 ? 84.712 57.340 57.142 1.00 33.37 ? 647 PHE B C 1 ATOM 10819 O O . PHE B 1 611 ? 84.570 57.717 55.985 1.00 35.58 ? 647 PHE B O 1 ATOM 10820 C CB . PHE B 1 611 ? 83.935 59.169 58.680 1.00 31.77 ? 647 PHE B CB 1 ATOM 10821 C CG . PHE B 1 611 ? 84.244 60.100 59.807 1.00 28.76 ? 647 PHE B CG 1 ATOM 10822 C CD1 . PHE B 1 611 ? 84.709 61.377 59.552 1.00 32.63 ? 647 PHE B CD1 1 ATOM 10823 C CD2 . PHE B 1 611 ? 84.091 59.690 61.123 1.00 30.00 ? 647 PHE B CD2 1 ATOM 10824 C CE1 . PHE B 1 611 ? 85.013 62.244 60.587 1.00 27.64 ? 647 PHE B CE1 1 ATOM 10825 C CE2 . PHE B 1 611 ? 84.386 60.550 62.167 1.00 31.14 ? 647 PHE B CE2 1 ATOM 10826 C CZ . PHE B 1 611 ? 84.844 61.832 61.896 1.00 31.49 ? 647 PHE B CZ 1 ATOM 10827 N N . LYS B 1 612 ? 84.511 56.082 57.525 1.00 35.94 ? 648 LYS B N 1 ATOM 10828 C CA . LYS B 1 612 ? 84.069 55.031 56.610 1.00 34.71 ? 648 LYS B CA 1 ATOM 10829 C C . LYS B 1 612 ? 82.575 55.140 56.338 1.00 32.40 ? 648 LYS B C 1 ATOM 10830 O O . LYS B 1 612 ? 82.122 54.945 55.223 1.00 37.33 ? 648 LYS B O 1 ATOM 10831 C CB . LYS B 1 612 ? 84.362 53.664 57.228 1.00 39.09 ? 648 LYS B CB 1 ATOM 10832 C CG . LYS B 1 612 ? 84.199 52.480 56.269 1.00 41.11 ? 648 LYS B CG 1 ATOM 10833 C CD . LYS B 1 612 ? 84.598 51.182 56.974 1.00 33.45 ? 648 LYS B CD 1 ATOM 10834 C CE . LYS B 1 612 ? 84.491 49.986 56.049 1.00 44.89 ? 648 LYS B CE 1 ATOM 10835 N NZ . LYS B 1 612 ? 83.116 49.888 55.497 1.00 51.80 ? 648 LYS B NZ 1 ATOM 10836 N N . CYS B 1 613 ? 81.802 55.448 57.371 1.00 33.46 ? 649 CYS B N 1 ATOM 10837 C CA . CYS B 1 613 ? 80.353 55.519 57.237 1.00 30.97 ? 649 CYS B CA 1 ATOM 10838 C C . CYS B 1 613 ? 79.753 56.375 58.346 1.00 32.55 ? 649 CYS B C 1 ATOM 10839 O O . CYS B 1 613 ? 80.432 56.737 59.308 1.00 30.45 ? 649 CYS B O 1 ATOM 10840 C CB . CYS B 1 613 ? 79.756 54.121 57.315 1.00 36.07 ? 649 CYS B CB 1 ATOM 10841 S SG . CYS B 1 613 ? 80.049 53.308 58.905 1.00 46.72 ? 649 CYS B SG 1 ATOM 10842 N N . GLY B 1 614 ? 78.472 56.687 58.221 1.00 29.77 ? 650 GLY B N 1 ATOM 10843 C CA . GLY B 1 614 ? 77.811 57.461 59.249 1.00 30.94 ? 650 GLY B CA 1 ATOM 10844 C C . GLY B 1 614 ? 76.311 57.378 59.162 1.00 29.97 ? 650 GLY B C 1 ATOM 10845 O O . GLY B 1 614 ? 75.761 56.972 58.137 1.00 26.33 ? 650 GLY B O 1 ATOM 10846 N N . ILE B 1 615 ? 75.650 57.778 60.246 1.00 28.26 ? 651 ILE B N 1 ATOM 10847 C CA . ILE B 1 615 ? 74.194 57.739 60.332 1.00 24.93 ? 651 ILE B CA 1 ATOM 10848 C C . ILE B 1 615 ? 73.678 59.101 60.772 1.00 26.84 ? 651 ILE B C 1 ATOM 10849 O O . ILE B 1 615 ? 74.127 59.630 61.788 1.00 27.73 ? 651 ILE B O 1 ATOM 10850 C CB . ILE B 1 615 ? 73.725 56.683 61.361 1.00 24.08 ? 651 ILE B CB 1 ATOM 10851 C CG1 . ILE B 1 615 ? 74.328 55.313 61.055 1.00 22.76 ? 651 ILE B CG1 1 ATOM 10852 C CG2 . ILE B 1 615 ? 72.206 56.622 61.391 1.00 25.26 ? 651 ILE B CG2 1 ATOM 10853 C CD1 . ILE B 1 615 ? 73.831 54.191 61.977 1.00 24.56 ? 651 ILE B CD1 1 ATOM 10854 N N . ALA B 1 616 ? 72.760 59.688 60.009 1.00 24.21 ? 652 ALA B N 1 ATOM 10855 C CA . ALA B 1 616 ? 72.145 60.942 60.429 1.00 23.27 ? 652 ALA B CA 1 ATOM 10856 C C . ALA B 1 616 ? 70.663 60.699 60.695 1.00 28.55 ? 652 ALA B C 1 ATOM 10857 O O . ALA B 1 616 ? 69.924 60.253 59.799 1.00 25.83 ? 652 ALA B O 1 ATOM 10858 C CB . ALA B 1 616 ? 72.321 61.995 59.372 1.00 23.42 ? 652 ALA B CB 1 ATOM 10859 N N . VAL B 1 617 ? 70.216 60.973 61.917 1.00 23.10 ? 653 VAL B N 1 ATOM 10860 C CA . VAL B 1 617 ? 68.805 60.779 62.239 1.00 25.42 ? 653 VAL B CA 1 ATOM 10861 C C . VAL B 1 617 ? 68.119 62.135 62.374 1.00 29.38 ? 653 VAL B C 1 ATOM 10862 O O . VAL B 1 617 ? 68.565 62.997 63.129 1.00 25.84 ? 653 VAL B O 1 ATOM 10863 C CB . VAL B 1 617 ? 68.592 59.936 63.522 1.00 24.90 ? 653 VAL B CB 1 ATOM 10864 C CG1 . VAL B 1 617 ? 67.100 59.631 63.707 1.00 22.38 ? 653 VAL B CG1 1 ATOM 10865 C CG2 . VAL B 1 617 ? 69.419 58.636 63.486 1.00 21.69 ? 653 VAL B CG2 1 ATOM 10866 N N . ALA B 1 618 ? 67.039 62.313 61.629 1.00 24.54 ? 654 ALA B N 1 ATOM 10867 C CA . ALA B 1 618 ? 66.279 63.560 61.623 1.00 25.86 ? 654 ALA B CA 1 ATOM 10868 C C . ALA B 1 618 ? 67.181 64.788 61.616 1.00 26.12 ? 654 ALA B C 1 ATOM 10869 O O . ALA B 1 618 ? 67.087 65.648 62.494 1.00 25.73 ? 654 ALA B O 1 ATOM 10870 C CB . ALA B 1 618 ? 65.299 63.594 62.787 1.00 22.06 ? 654 ALA B CB 1 ATOM 10871 N N . PRO B 1 619 ? 68.051 64.883 60.603 1.00 24.81 ? 655 PRO B N 1 ATOM 10872 C CA . PRO B 1 619 ? 69.007 65.985 60.534 1.00 25.31 ? 655 PRO B CA 1 ATOM 10873 C C . PRO B 1 619 ? 68.392 67.286 60.037 1.00 24.50 ? 655 PRO B C 1 ATOM 10874 O O . PRO B 1 619 ? 67.452 67.263 59.239 1.00 23.86 ? 655 PRO B O 1 ATOM 10875 C CB . PRO B 1 619 ? 70.035 65.472 59.521 1.00 24.95 ? 655 PRO B CB 1 ATOM 10876 C CG . PRO B 1 619 ? 69.213 64.627 58.575 1.00 24.56 ? 655 PRO B CG 1 ATOM 10877 C CD . PRO B 1 619 ? 68.154 63.975 59.441 1.00 23.75 ? 655 PRO B CD 1 ATOM 10878 N N . VAL B 1 620 ? 68.884 68.420 60.534 1.00 24.50 ? 656 VAL B N 1 ATOM 10879 C CA . VAL B 1 620 ? 68.673 69.671 59.815 1.00 23.96 ? 656 VAL B CA 1 ATOM 10880 C C . VAL B 1 620 ? 69.550 69.597 58.551 1.00 25.05 ? 656 VAL B C 1 ATOM 10881 O O . VAL B 1 620 ? 70.653 69.036 58.598 1.00 25.36 ? 656 VAL B O 1 ATOM 10882 C CB . VAL B 1 620 ? 69.086 70.896 60.656 1.00 26.18 ? 656 VAL B CB 1 ATOM 10883 C CG1 . VAL B 1 620 ? 69.382 72.098 59.743 1.00 24.71 ? 656 VAL B CG1 1 ATOM 10884 C CG2 . VAL B 1 620 ? 67.994 71.248 61.655 1.00 24.24 ? 656 VAL B CG2 1 ATOM 10885 N N . SER B 1 621 ? 69.090 70.137 57.424 1.00 23.01 ? 657 SER B N 1 ATOM 10886 C CA . SER B 1 621 ? 69.937 70.137 56.225 1.00 25.34 ? 657 SER B CA 1 ATOM 10887 C C . SER B 1 621 ? 70.195 71.542 55.718 1.00 23.72 ? 657 SER B C 1 ATOM 10888 O O . SER B 1 621 ? 71.169 71.778 55.033 1.00 28.01 ? 657 SER B O 1 ATOM 10889 C CB . SER B 1 621 ? 69.333 69.292 55.095 1.00 22.61 ? 657 SER B CB 1 ATOM 10890 O OG . SER B 1 621 ? 68.111 69.859 54.645 1.00 22.80 ? 657 SER B OG 1 ATOM 10891 N N . ARG B 1 622 ? 69.330 72.476 56.076 1.00 25.06 ? 658 ARG B N 1 ATOM 10892 C CA . ARG B 1 622 ? 69.449 73.848 55.604 1.00 27.54 ? 658 ARG B CA 1 ATOM 10893 C C . ARG B 1 622 ? 68.801 74.723 56.672 1.00 27.86 ? 658 ARG B C 1 ATOM 10894 O O . ARG B 1 622 ? 67.674 74.442 57.088 1.00 26.36 ? 658 ARG B O 1 ATOM 10895 C CB . ARG B 1 622 ? 68.722 73.963 54.259 1.00 29.78 ? 658 ARG B CB 1 ATOM 10896 C CG . ARG B 1 622 ? 68.766 75.298 53.582 1.00 31.27 ? 658 ARG B CG 1 ATOM 10897 C CD . ARG B 1 622 ? 68.223 75.167 52.152 1.00 35.32 ? 658 ARG B CD 1 ATOM 10898 N NE . ARG B 1 622 ? 68.287 76.422 51.411 1.00 40.93 ? 658 ARG B NE 1 ATOM 10899 C CZ . ARG B 1 622 ? 67.274 77.279 51.285 1.00 45.56 ? 658 ARG B CZ 1 ATOM 10900 N NH1 . ARG B 1 622 ? 66.097 77.023 51.846 1.00 43.72 ? 658 ARG B NH1 1 ATOM 10901 N NH2 . ARG B 1 622 ? 67.433 78.399 50.592 1.00 42.32 ? 658 ARG B NH2 1 ATOM 10902 N N . TRP B 1 623 ? 69.502 75.759 57.143 1.00 26.60 ? 659 TRP B N 1 ATOM 10903 C CA . TRP B 1 623 ? 68.993 76.541 58.287 1.00 28.51 ? 659 TRP B CA 1 ATOM 10904 C C . TRP B 1 623 ? 67.705 77.303 57.981 1.00 28.84 ? 659 TRP B C 1 ATOM 10905 O O . TRP B 1 623 ? 66.878 77.523 58.866 1.00 28.51 ? 659 TRP B O 1 ATOM 10906 C CB . TRP B 1 623 ? 70.092 77.422 58.930 1.00 28.38 ? 659 TRP B CB 1 ATOM 10907 C CG . TRP B 1 623 ? 71.051 76.547 59.653 1.00 23.14 ? 659 TRP B CG 1 ATOM 10908 C CD1 . TRP B 1 623 ? 72.343 76.259 59.302 1.00 25.33 ? 659 TRP B CD1 1 ATOM 10909 C CD2 . TRP B 1 623 ? 70.755 75.751 60.798 1.00 25.38 ? 659 TRP B CD2 1 ATOM 10910 N NE1 . TRP B 1 623 ? 72.883 75.355 60.192 1.00 24.54 ? 659 TRP B NE1 1 ATOM 10911 C CE2 . TRP B 1 623 ? 71.924 75.030 61.120 1.00 25.80 ? 659 TRP B CE2 1 ATOM 10912 C CE3 . TRP B 1 623 ? 69.623 75.601 61.608 1.00 24.34 ? 659 TRP B CE3 1 ATOM 10913 C CZ2 . TRP B 1 623 ? 71.982 74.164 62.202 1.00 22.21 ? 659 TRP B CZ2 1 ATOM 10914 C CZ3 . TRP B 1 623 ? 69.687 74.743 62.692 1.00 25.68 ? 659 TRP B CZ3 1 ATOM 10915 C CH2 . TRP B 1 623 ? 70.855 74.029 62.974 1.00 27.56 ? 659 TRP B CH2 1 ATOM 10916 N N . GLU B 1 624 ? 67.506 77.653 56.718 1.00 26.75 ? 660 GLU B N 1 ATOM 10917 C CA . GLU B 1 624 ? 66.243 78.262 56.312 1.00 29.06 ? 660 GLU B CA 1 ATOM 10918 C C . GLU B 1 624 ? 65.013 77.382 56.600 1.00 26.16 ? 660 GLU B C 1 ATOM 10919 O O . GLU B 1 624 ? 63.895 77.893 56.641 1.00 24.28 ? 660 GLU B O 1 ATOM 10920 C CB . GLU B 1 624 ? 66.291 78.695 54.839 1.00 31.30 ? 660 GLU B CB 1 ATOM 10921 C CG . GLU B 1 624 ? 67.006 80.040 54.639 1.00 37.06 ? 660 GLU B CG 1 ATOM 10922 C CD . GLU B 1 624 ? 67.580 80.231 53.233 1.00 43.90 ? 660 GLU B CD 1 ATOM 10923 O OE1 . GLU B 1 624 ? 68.724 79.778 52.995 1.00 40.29 ? 660 GLU B OE1 1 ATOM 10924 O OE2 . GLU B 1 624 ? 66.892 80.845 52.375 1.00 49.23 ? 660 GLU B OE2 1 ATOM 10925 N N . TYR B 1 625 ? 65.218 76.079 56.809 1.00 23.02 ? 661 TYR B N 1 ATOM 10926 C CA . TYR B 1 625 ? 64.095 75.167 57.080 1.00 24.51 ? 661 TYR B CA 1 ATOM 10927 C C . TYR B 1 625 ? 63.717 75.031 58.543 1.00 27.66 ? 661 TYR B C 1 ATOM 10928 O O . TYR B 1 625 ? 62.636 74.523 58.850 1.00 26.13 ? 661 TYR B O 1 ATOM 10929 C CB . TYR B 1 625 ? 64.374 73.752 56.553 1.00 23.92 ? 661 TYR B CB 1 ATOM 10930 C CG . TYR B 1 625 ? 64.568 73.631 55.054 1.00 26.99 ? 661 TYR B CG 1 ATOM 10931 C CD1 . TYR B 1 625 ? 64.052 74.569 54.162 1.00 29.52 ? 661 TYR B CD1 1 ATOM 10932 C CD2 . TYR B 1 625 ? 65.274 72.559 54.534 1.00 26.12 ? 661 TYR B CD2 1 ATOM 10933 C CE1 . TYR B 1 625 ? 64.241 74.420 52.780 1.00 26.16 ? 661 TYR B CE1 1 ATOM 10934 C CE2 . TYR B 1 625 ? 65.464 72.412 53.184 1.00 27.14 ? 661 TYR B CE2 1 ATOM 10935 C CZ . TYR B 1 625 ? 64.961 73.339 52.312 1.00 28.36 ? 661 TYR B CZ 1 ATOM 10936 O OH . TYR B 1 625 ? 65.197 73.142 50.958 1.00 29.44 ? 661 TYR B OH 1 ATOM 10937 N N . TYR B 1 626 ? 64.621 75.427 59.443 1.00 27.02 ? 662 TYR B N 1 ATOM 10938 C CA . TYR B 1 626 ? 64.385 75.285 60.875 1.00 23.59 ? 662 TYR B CA 1 ATOM 10939 C C . TYR B 1 626 ? 63.736 76.537 61.474 1.00 25.12 ? 662 TYR B C 1 ATOM 10940 O O . TYR B 1 626 ? 63.610 77.561 60.803 1.00 26.54 ? 662 TYR B O 1 ATOM 10941 C CB . TYR B 1 626 ? 65.668 74.899 61.629 1.00 23.50 ? 662 TYR B CB 1 ATOM 10942 C CG . TYR B 1 626 ? 65.335 74.274 62.971 1.00 25.64 ? 662 TYR B CG 1 ATOM 10943 C CD1 . TYR B 1 626 ? 64.450 73.204 63.047 1.00 23.99 ? 662 TYR B CD1 1 ATOM 10944 C CD2 . TYR B 1 626 ? 65.855 74.787 64.164 1.00 27.62 ? 662 TYR B CD2 1 ATOM 10945 C CE1 . TYR B 1 626 ? 64.105 72.637 64.261 1.00 23.15 ? 662 TYR B CE1 1 ATOM 10946 C CE2 . TYR B 1 626 ? 65.525 74.219 65.391 1.00 25.68 ? 662 TYR B CE2 1 ATOM 10947 C CZ . TYR B 1 626 ? 64.643 73.155 65.428 1.00 28.00 ? 662 TYR B CZ 1 ATOM 10948 O OH . TYR B 1 626 ? 64.289 72.599 66.626 1.00 26.15 ? 662 TYR B OH 1 ATOM 10949 N N . ASP B 1 627 ? 63.304 76.451 62.726 1.00 24.33 ? 663 ASP B N 1 ATOM 10950 C CA . ASP B 1 627 ? 62.482 77.507 63.306 1.00 23.47 ? 663 ASP B CA 1 ATOM 10951 C C . ASP B 1 627 ? 63.226 78.825 63.601 1.00 24.44 ? 663 ASP B C 1 ATOM 10952 O O . ASP B 1 627 ? 64.429 78.844 63.828 1.00 25.92 ? 663 ASP B O 1 ATOM 10953 C CB . ASP B 1 627 ? 61.675 76.998 64.522 1.00 25.30 ? 663 ASP B CB 1 ATOM 10954 C CG . ASP B 1 627 ? 62.491 76.930 65.819 1.00 26.74 ? 663 ASP B CG 1 ATOM 10955 O OD1 . ASP B 1 627 ? 63.026 77.957 66.275 1.00 28.09 ? 663 ASP B OD1 1 ATOM 10956 O OD2 . ASP B 1 627 ? 62.570 75.840 66.413 1.00 28.01 ? 663 ASP B OD2 1 ATOM 10957 N N . SER B 1 628 ? 62.490 79.930 63.592 1.00 24.66 ? 664 SER B N 1 ATOM 10958 C CA . SER B 1 628 ? 63.117 81.236 63.679 1.00 26.95 ? 664 SER B CA 1 ATOM 10959 C C . SER B 1 628 ? 63.848 81.451 64.999 1.00 28.09 ? 664 SER B C 1 ATOM 10960 O O . SER B 1 628 ? 64.986 81.911 65.001 1.00 31.81 ? 664 SER B O 1 ATOM 10961 C CB . SER B 1 628 ? 62.083 82.337 63.468 1.00 26.13 ? 664 SER B CB 1 ATOM 10962 O OG . SER B 1 628 ? 61.012 82.199 64.386 1.00 28.90 ? 664 SER B OG 1 ATOM 10963 N N . VAL B 1 629 ? 63.208 81.141 66.123 1.00 25.62 ? 665 VAL B N 1 ATOM 10964 C CA . VAL B 1 629 ? 63.793 81.502 67.410 1.00 24.44 ? 665 VAL B CA 1 ATOM 10965 C C . VAL B 1 629 ? 65.143 80.826 67.626 1.00 28.32 ? 665 VAL B C 1 ATOM 10966 O O . VAL B 1 629 ? 66.108 81.459 68.049 1.00 31.51 ? 665 VAL B O 1 ATOM 10967 C CB . VAL B 1 629 ? 62.845 81.187 68.592 1.00 28.52 ? 665 VAL B CB 1 ATOM 10968 C CG1 . VAL B 1 629 ? 63.524 81.530 69.933 1.00 28.59 ? 665 VAL B CG1 1 ATOM 10969 C CG2 . VAL B 1 629 ? 61.550 81.964 68.437 1.00 29.03 ? 665 VAL B CG2 1 ATOM 10970 N N . TYR B 1 630 ? 65.218 79.536 67.335 1.00 23.69 ? 666 TYR B N 1 ATOM 10971 C CA . TYR B 1 630 ? 66.470 78.815 67.503 1.00 24.89 ? 666 TYR B CA 1 ATOM 10972 C C . TYR B 1 630 ? 67.493 79.261 66.479 1.00 27.77 ? 666 TYR B C 1 ATOM 10973 O O . TYR B 1 630 ? 68.628 79.591 66.811 1.00 27.37 ? 666 TYR B O 1 ATOM 10974 C CB . TYR B 1 630 ? 66.252 77.317 67.343 1.00 25.15 ? 666 TYR B CB 1 ATOM 10975 C CG . TYR B 1 630 ? 67.497 76.501 67.602 1.00 27.41 ? 666 TYR B CG 1 ATOM 10976 C CD1 . TYR B 1 630 ? 68.399 76.223 66.583 1.00 25.14 ? 666 TYR B CD1 1 ATOM 10977 C CD2 . TYR B 1 630 ? 67.766 76.005 68.868 1.00 27.83 ? 666 TYR B CD2 1 ATOM 10978 C CE1 . TYR B 1 630 ? 69.542 75.476 66.827 1.00 25.22 ? 666 TYR B CE1 1 ATOM 10979 C CE2 . TYR B 1 630 ? 68.897 75.252 69.120 1.00 27.87 ? 666 TYR B CE2 1 ATOM 10980 C CZ . TYR B 1 630 ? 69.779 74.987 68.101 1.00 29.44 ? 666 TYR B CZ 1 ATOM 10981 O OH . TYR B 1 630 ? 70.908 74.242 68.367 1.00 25.95 ? 666 TYR B OH 1 ATOM 10982 N N . THR B 1 631 ? 67.093 79.242 65.215 1.00 25.45 ? 667 THR B N 1 ATOM 10983 C CA . THR B 1 631 ? 68.045 79.459 64.134 1.00 24.68 ? 667 THR B CA 1 ATOM 10984 C C . THR B 1 631 ? 68.642 80.855 64.161 1.00 25.25 ? 667 THR B C 1 ATOM 10985 O O . THR B 1 631 ? 69.860 81.017 64.112 1.00 30.01 ? 667 THR B O 1 ATOM 10986 C CB . THR B 1 631 ? 67.402 79.204 62.771 1.00 25.20 ? 667 THR B CB 1 ATOM 10987 O OG1 . THR B 1 631 ? 66.897 77.864 62.747 1.00 25.81 ? 667 THR B OG1 1 ATOM 10988 C CG2 . THR B 1 631 ? 68.423 79.390 61.658 1.00 24.98 ? 667 THR B CG2 1 ATOM 10989 N N . GLU B 1 632 ? 67.792 81.867 64.238 1.00 24.92 ? 668 GLU B N 1 ATOM 10990 C CA . GLU B 1 632 ? 68.271 83.238 64.166 1.00 26.38 ? 668 GLU B CA 1 ATOM 10991 C C . GLU B 1 632 ? 69.085 83.617 65.409 1.00 28.80 ? 668 GLU B C 1 ATOM 10992 O O . GLU B 1 632 ? 69.838 84.589 65.405 1.00 26.70 ? 668 GLU B O 1 ATOM 10993 C CB . GLU B 1 632 ? 67.097 84.195 63.986 1.00 28.34 ? 668 GLU B CB 1 ATOM 10994 C CG . GLU B 1 632 ? 66.221 83.855 62.806 1.00 28.24 ? 668 GLU B CG 1 ATOM 10995 C CD . GLU B 1 632 ? 64.869 84.540 62.845 1.00 30.77 ? 668 GLU B CD 1 ATOM 10996 O OE1 . GLU B 1 632 ? 64.656 85.433 63.698 1.00 32.04 ? 668 GLU B OE1 1 ATOM 10997 O OE2 . GLU B 1 632 ? 63.999 84.166 62.024 1.00 31.32 ? 668 GLU B OE2 1 ATOM 10998 N N . ARG B 1 633 ? 68.953 82.845 66.482 1.00 26.99 ? 669 ARG B N 1 ATOM 10999 C CA . ARG B 1 633 ? 69.736 83.140 67.677 1.00 26.19 ? 669 ARG B CA 1 ATOM 11000 C C . ARG B 1 633 ? 71.213 82.985 67.357 1.00 28.13 ? 669 ARG B C 1 ATOM 11001 O O . ARG B 1 633 ? 72.039 83.772 67.817 1.00 27.39 ? 669 ARG B O 1 ATOM 11002 C CB . ARG B 1 633 ? 69.337 82.223 68.836 1.00 26.28 ? 669 ARG B CB 1 ATOM 11003 C CG . ARG B 1 633 ? 69.919 82.622 70.179 1.00 27.34 ? 669 ARG B CG 1 ATOM 11004 C CD . ARG B 1 633 ? 69.003 82.126 71.289 1.00 33.12 ? 669 ARG B CD 1 ATOM 11005 N NE . ARG B 1 633 ? 68.952 80.686 71.288 1.00 30.93 ? 669 ARG B NE 1 ATOM 11006 C CZ . ARG B 1 633 ? 67.868 79.950 71.509 1.00 31.99 ? 669 ARG B CZ 1 ATOM 11007 N NH1 . ARG B 1 633 ? 66.694 80.505 71.764 1.00 27.49 ? 669 ARG B NH1 1 ATOM 11008 N NH2 . ARG B 1 633 ? 67.982 78.629 71.475 1.00 34.34 ? 669 ARG B NH2 1 ATOM 11009 N N . TYR B 1 634 ? 71.548 81.974 66.558 1.00 27.15 ? 670 TYR B N 1 ATOM 11010 C CA . TYR B 1 634 ? 72.946 81.742 66.215 1.00 27.68 ? 670 TYR B CA 1 ATOM 11011 C C . TYR B 1 634 ? 73.324 82.316 64.857 1.00 32.14 ? 670 TYR B C 1 ATOM 11012 O O . TYR B 1 634 ? 74.491 82.628 64.630 1.00 34.33 ? 670 TYR B O 1 ATOM 11013 C CB . TYR B 1 634 ? 73.286 80.252 66.274 1.00 26.51 ? 670 TYR B CB 1 ATOM 11014 C CG . TYR B 1 634 ? 72.726 79.609 67.520 1.00 26.91 ? 670 TYR B CG 1 ATOM 11015 C CD1 . TYR B 1 634 ? 73.266 79.894 68.771 1.00 28.64 ? 670 TYR B CD1 1 ATOM 11016 C CD2 . TYR B 1 634 ? 71.629 78.766 67.458 1.00 28.78 ? 670 TYR B CD2 1 ATOM 11017 C CE1 . TYR B 1 634 ? 72.744 79.323 69.925 1.00 27.37 ? 670 TYR B CE1 1 ATOM 11018 C CE2 . TYR B 1 634 ? 71.096 78.183 68.612 1.00 26.03 ? 670 TYR B CE2 1 ATOM 11019 C CZ . TYR B 1 634 ? 71.657 78.476 69.835 1.00 26.79 ? 670 TYR B CZ 1 ATOM 11020 O OH . TYR B 1 634 ? 71.133 77.920 70.975 1.00 26.31 ? 670 TYR B OH 1 ATOM 11021 N N . MET B 1 635 ? 72.344 82.458 63.966 1.00 28.24 ? 671 MET B N 1 ATOM 11022 C CA . MET B 1 635 ? 72.633 82.740 62.556 1.00 27.62 ? 671 MET B CA 1 ATOM 11023 C C . MET B 1 635 ? 72.234 84.131 62.059 1.00 31.01 ? 671 MET B C 1 ATOM 11024 O O . MET B 1 635 ? 72.534 84.482 60.926 1.00 32.41 ? 671 MET B O 1 ATOM 11025 C CB . MET B 1 635 ? 71.953 81.684 61.663 1.00 28.26 ? 671 MET B CB 1 ATOM 11026 C CG . MET B 1 635 ? 72.586 80.307 61.735 1.00 26.91 ? 671 MET B CG 1 ATOM 11027 S SD . MET B 1 635 ? 74.182 80.308 60.906 1.00 34.00 ? 671 MET B SD 1 ATOM 11028 C CE . MET B 1 635 ? 73.634 80.301 59.197 1.00 33.67 ? 671 MET B CE 1 ATOM 11029 N N . GLY B 1 636 ? 71.554 84.918 62.886 1.00 30.39 ? 672 GLY B N 1 ATOM 11030 C CA . GLY B 1 636 ? 70.958 86.152 62.408 1.00 32.26 ? 672 GLY B CA 1 ATOM 11031 C C . GLY B 1 636 ? 69.880 85.831 61.389 1.00 34.13 ? 672 GLY B C 1 ATOM 11032 O O . GLY B 1 636 ? 69.346 84.725 61.369 1.00 33.24 ? 672 GLY B O 1 ATOM 11033 N N . LEU B 1 637 ? 69.549 86.795 60.542 1.00 34.56 ? 673 LEU B N 1 ATOM 11034 C CA . LEU B 1 637 ? 68.489 86.612 59.553 1.00 34.49 ? 673 LEU B CA 1 ATOM 11035 C C . LEU B 1 637 ? 69.051 86.216 58.196 1.00 35.20 ? 673 LEU B C 1 ATOM 11036 O O . LEU B 1 637 ? 70.171 86.599 57.858 1.00 36.05 ? 673 LEU B O 1 ATOM 11037 C CB . LEU B 1 637 ? 67.677 87.897 59.410 1.00 36.55 ? 673 LEU B CB 1 ATOM 11038 C CG . LEU B 1 637 ? 66.912 88.320 60.658 1.00 36.24 ? 673 LEU B CG 1 ATOM 11039 C CD1 . LEU B 1 637 ? 66.272 89.684 60.454 1.00 42.17 ? 673 LEU B CD1 1 ATOM 11040 C CD2 . LEU B 1 637 ? 65.857 87.273 61.003 1.00 36.05 ? 673 LEU B CD2 1 ATOM 11041 N N . PRO B 1 638 ? 68.271 85.447 57.412 1.00 33.92 ? 674 PRO B N 1 ATOM 11042 C CA . PRO B 1 638 ? 68.696 85.012 56.075 1.00 35.80 ? 674 PRO B CA 1 ATOM 11043 C C . PRO B 1 638 ? 68.381 86.066 55.009 1.00 37.97 ? 674 PRO B C 1 ATOM 11044 O O . PRO B 1 638 ? 67.642 85.773 54.063 1.00 36.32 ? 674 PRO B O 1 ATOM 11045 C CB . PRO B 1 638 ? 67.832 83.779 55.831 1.00 31.36 ? 674 PRO B CB 1 ATOM 11046 C CG . PRO B 1 638 ? 66.544 84.115 56.531 1.00 32.33 ? 674 PRO B CG 1 ATOM 11047 C CD . PRO B 1 638 ? 66.933 84.932 57.752 1.00 32.54 ? 674 PRO B CD 1 ATOM 11048 N N . THR B 1 639 ? 68.922 87.271 55.175 1.00 39.89 ? 675 THR B N 1 ATOM 11049 C CA . THR B 1 639 ? 68.774 88.334 54.179 1.00 41.10 ? 675 THR B CA 1 ATOM 11050 C C . THR B 1 639 ? 70.150 88.767 53.662 1.00 42.83 ? 675 THR B C 1 ATOM 11051 O O . THR B 1 639 ? 71.167 88.542 54.330 1.00 40.06 ? 675 THR B O 1 ATOM 11052 C CB . THR B 1 639 ? 68.031 89.549 54.760 1.00 42.05 ? 675 THR B CB 1 ATOM 11053 O OG1 . THR B 1 639 ? 68.728 90.024 55.919 1.00 44.62 ? 675 THR B OG1 1 ATOM 11054 C CG2 . THR B 1 639 ? 66.598 89.174 55.154 1.00 37.77 ? 675 THR B CG2 1 ATOM 11055 N N . PRO B 1 640 ? 70.195 89.378 52.465 1.00 39.55 ? 676 PRO B N 1 ATOM 11056 C CA . PRO B 1 640 ? 71.477 89.861 51.932 1.00 44.83 ? 676 PRO B CA 1 ATOM 11057 C C . PRO B 1 640 ? 72.138 90.880 52.864 1.00 42.78 ? 676 PRO B C 1 ATOM 11058 O O . PRO B 1 640 ? 73.366 90.900 52.982 1.00 43.56 ? 676 PRO B O 1 ATOM 11059 C CB . PRO B 1 640 ? 71.086 90.517 50.603 1.00 44.61 ? 676 PRO B CB 1 ATOM 11060 C CG . PRO B 1 640 ? 69.808 89.841 50.209 1.00 46.34 ? 676 PRO B CG 1 ATOM 11061 C CD . PRO B 1 640 ? 69.090 89.553 51.507 1.00 44.69 ? 676 PRO B CD 1 ATOM 11062 N N . GLU B 1 641 ? 71.324 91.698 53.525 1.00 45.93 ? 677 GLU B N 1 ATOM 11063 C CA . GLU B 1 641 ? 71.812 92.681 54.494 1.00 44.34 ? 677 GLU B CA 1 ATOM 11064 C C . GLU B 1 641 ? 72.453 92.051 55.742 1.00 49.45 ? 677 GLU B C 1 ATOM 11065 O O . GLU B 1 641 ? 73.276 92.688 56.410 1.00 45.89 ? 677 GLU B O 1 ATOM 11066 C CB . GLU B 1 641 ? 70.669 93.612 54.929 1.00 49.38 ? 677 GLU B CB 1 ATOM 11067 C CG . GLU B 1 641 ? 69.994 94.385 53.796 1.00 52.25 ? 677 GLU B CG 1 ATOM 11068 C CD . GLU B 1 641 ? 68.987 93.548 53.009 1.00 60.04 ? 677 GLU B CD 1 ATOM 11069 O OE1 . GLU B 1 641 ? 68.367 92.633 53.600 1.00 54.50 ? 677 GLU B OE1 1 ATOM 11070 O OE2 . GLU B 1 641 ? 68.809 93.813 51.792 1.00 67.76 ? 677 GLU B OE2 1 ATOM 11071 N N . ASP B 1 642 ? 72.076 90.813 56.067 1.00 44.19 ? 678 ASP B N 1 ATOM 11072 C CA . ASP B 1 642 ? 72.543 90.182 57.305 1.00 40.59 ? 678 ASP B CA 1 ATOM 11073 C C . ASP B 1 642 ? 73.419 88.986 56.993 1.00 40.45 ? 678 ASP B C 1 ATOM 11074 O O . ASP B 1 642 ? 74.576 89.151 56.614 1.00 41.73 ? 678 ASP B O 1 ATOM 11075 C CB . ASP B 1 642 ? 71.357 89.770 58.184 1.00 40.47 ? 678 ASP B CB 1 ATOM 11076 C CG . ASP B 1 642 ? 71.748 89.538 59.653 1.00 42.73 ? 678 ASP B CG 1 ATOM 11077 O OD1 . ASP B 1 642 ? 72.959 89.403 59.959 1.00 40.26 ? 678 ASP B OD1 1 ATOM 11078 O OD2 . ASP B 1 642 ? 70.825 89.480 60.505 1.00 44.49 ? 678 ASP B OD2 1 ATOM 11079 N N . ASN B 1 643 ? 72.871 87.780 57.115 1.00 36.44 ? 679 ASN B N 1 ATOM 11080 C CA . ASN B 1 643 ? 73.712 86.589 57.040 1.00 34.51 ? 679 ASN B CA 1 ATOM 11081 C C . ASN B 1 643 ? 73.338 85.579 55.958 1.00 37.90 ? 679 ASN B C 1 ATOM 11082 O O . ASN B 1 643 ? 73.752 84.415 56.033 1.00 35.37 ? 679 ASN B O 1 ATOM 11083 C CB . ASN B 1 643 ? 73.743 85.887 58.404 1.00 33.33 ? 679 ASN B CB 1 ATOM 11084 C CG . ASN B 1 643 ? 75.013 85.084 58.618 1.00 36.99 ? 679 ASN B CG 1 ATOM 11085 O OD1 . ASN B 1 643 ? 76.032 85.331 57.969 1.00 34.24 ? 679 ASN B OD1 1 ATOM 11086 N ND2 . ASN B 1 643 ? 74.962 84.120 59.535 1.00 31.96 ? 679 ASN B ND2 1 ATOM 11087 N N . LEU B 1 644 ? 72.564 86.008 54.962 1.00 32.83 ? 680 LEU B N 1 ATOM 11088 C CA . LEU B 1 644 ? 72.107 85.099 53.905 1.00 37.97 ? 680 LEU B CA 1 ATOM 11089 C C . LEU B 1 644 ? 73.215 84.244 53.306 1.00 37.37 ? 680 LEU B C 1 ATOM 11090 O O . LEU B 1 644 ? 73.023 83.058 53.056 1.00 40.74 ? 680 LEU B O 1 ATOM 11091 C CB . LEU B 1 644 ? 71.383 85.848 52.780 1.00 37.13 ? 680 LEU B CB 1 ATOM 11092 C CG . LEU B 1 644 ? 70.907 84.906 51.673 1.00 42.88 ? 680 LEU B CG 1 ATOM 11093 C CD1 . LEU B 1 644 ? 69.909 83.910 52.244 1.00 44.23 ? 680 LEU B CD1 1 ATOM 11094 C CD2 . LEU B 1 644 ? 70.287 85.663 50.498 1.00 39.67 ? 680 LEU B CD2 1 ATOM 11095 N N . ASP B 1 645 ? 74.371 84.851 53.072 1.00 36.99 ? 681 ASP B N 1 ATOM 11096 C CA . ASP B 1 645 ? 75.481 84.153 52.443 1.00 36.91 ? 681 ASP B CA 1 ATOM 11097 C C . ASP B 1 645 ? 75.912 82.909 53.200 1.00 38.30 ? 681 ASP B C 1 ATOM 11098 O O . ASP B 1 645 ? 76.221 81.880 52.589 1.00 35.42 ? 681 ASP B O 1 ATOM 11099 C CB . ASP B 1 645 ? 76.675 85.089 52.264 1.00 42.69 ? 681 ASP B CB 1 ATOM 11100 C CG . ASP B 1 645 ? 76.513 86.009 51.064 1.00 53.63 ? 681 ASP B CG 1 ATOM 11101 O OD1 . ASP B 1 645 ? 76.007 85.535 50.020 1.00 43.96 ? 681 ASP B OD1 1 ATOM 11102 O OD2 . ASP B 1 645 ? 76.888 87.201 51.171 1.00 62.53 ? 681 ASP B OD2 1 ATOM 11103 N N . HIS B 1 646 ? 75.972 82.991 54.523 1.00 35.72 ? 682 HIS B N 1 ATOM 11104 C CA . HIS B 1 646 ? 76.380 81.806 55.261 1.00 35.65 ? 682 HIS B CA 1 ATOM 11105 C C . HIS B 1 646 ? 75.252 80.779 55.414 1.00 34.68 ? 682 HIS B C 1 ATOM 11106 O O . HIS B 1 646 ? 75.513 79.574 55.492 1.00 35.88 ? 682 HIS B O 1 ATOM 11107 C CB . HIS B 1 646 ? 77.020 82.110 56.606 1.00 34.10 ? 682 HIS B CB 1 ATOM 11108 C CG . HIS B 1 646 ? 77.491 80.871 57.299 1.00 37.60 ? 682 HIS B CG 1 ATOM 11109 N ND1 . HIS B 1 646 ? 78.630 80.192 56.916 1.00 38.52 ? 682 HIS B ND1 1 ATOM 11110 C CD2 . HIS B 1 646 ? 76.933 80.138 58.294 1.00 37.52 ? 682 HIS B CD2 1 ATOM 11111 C CE1 . HIS B 1 646 ? 78.776 79.118 57.675 1.00 39.20 ? 682 HIS B CE1 1 ATOM 11112 N NE2 . HIS B 1 646 ? 77.759 79.063 58.521 1.00 31.52 ? 682 HIS B NE2 1 ATOM 11113 N N . TYR B 1 647 ? 74.010 81.255 55.460 1.00 34.04 ? 683 TYR B N 1 ATOM 11114 C CA . TYR B 1 647 ? 72.864 80.362 55.383 1.00 32.46 ? 683 TYR B CA 1 ATOM 11115 C C . TYR B 1 647 ? 73.028 79.470 54.160 1.00 35.96 ? 683 TYR B C 1 ATOM 11116 O O . TYR B 1 647 ? 72.779 78.269 54.236 1.00 34.32 ? 683 TYR B O 1 ATOM 11117 C CB . TYR B 1 647 ? 71.559 81.141 55.257 1.00 34.07 ? 683 TYR B CB 1 ATOM 11118 C CG . TYR B 1 647 ? 70.835 81.458 56.561 1.00 33.04 ? 683 TYR B CG 1 ATOM 11119 C CD1 . TYR B 1 647 ? 71.109 82.624 57.256 1.00 31.55 ? 683 TYR B CD1 1 ATOM 11120 C CD2 . TYR B 1 647 ? 69.844 80.616 57.065 1.00 33.94 ? 683 TYR B CD2 1 ATOM 11121 C CE1 . TYR B 1 647 ? 70.449 82.945 58.426 1.00 32.45 ? 683 TYR B CE1 1 ATOM 11122 C CE2 . TYR B 1 647 ? 69.170 80.925 58.261 1.00 30.97 ? 683 TYR B CE2 1 ATOM 11123 C CZ . TYR B 1 647 ? 69.482 82.097 58.924 1.00 31.66 ? 683 TYR B CZ 1 ATOM 11124 O OH . TYR B 1 647 ? 68.841 82.458 60.081 1.00 29.65 ? 683 TYR B OH 1 ATOM 11125 N N . ARG B 1 648 ? 73.455 80.052 53.036 1.00 32.96 ? 684 ARG B N 1 ATOM 11126 C CA . ARG B 1 648 ? 73.568 79.290 51.780 1.00 35.57 ? 684 ARG B CA 1 ATOM 11127 C C . ARG B 1 648 ? 74.831 78.447 51.684 1.00 35.65 ? 684 ARG B C 1 ATOM 11128 O O . ARG B 1 648 ? 74.868 77.469 50.948 1.00 32.25 ? 684 ARG B O 1 ATOM 11129 C CB . ARG B 1 648 ? 73.488 80.204 50.550 1.00 39.46 ? 684 ARG B CB 1 ATOM 11130 C CG . ARG B 1 648 ? 72.108 80.271 49.939 1.00 42.43 ? 684 ARG B CG 1 ATOM 11131 C CD . ARG B 1 648 ? 71.309 81.339 50.602 1.00 47.01 ? 684 ARG B CD 1 ATOM 11132 N NE . ARG B 1 648 ? 69.868 81.081 50.616 1.00 54.57 ? 684 ARG B NE 1 ATOM 11133 C CZ . ARG B 1 648 ? 69.029 81.439 49.649 1.00 54.59 ? 684 ARG B CZ 1 ATOM 11134 N NH1 . ARG B 1 648 ? 69.489 82.045 48.560 1.00 52.72 ? 684 ARG B NH1 1 ATOM 11135 N NH2 . ARG B 1 648 ? 67.731 81.185 49.771 1.00 52.94 ? 684 ARG B NH2 1 ATOM 11136 N N . ASN B 1 649 ? 75.865 78.825 52.423 1.00 31.64 ? 685 ASN B N 1 ATOM 11137 C CA . ASN B 1 649 ? 77.124 78.102 52.363 1.00 34.76 ? 685 ASN B CA 1 ATOM 11138 C C . ASN B 1 649 ? 77.165 76.915 53.347 1.00 37.19 ? 685 ASN B C 1 ATOM 11139 O O . ASN B 1 649 ? 78.101 76.109 53.323 1.00 37.55 ? 685 ASN B O 1 ATOM 11140 C CB . ASN B 1 649 ? 78.291 79.072 52.627 1.00 40.09 ? 685 ASN B CB 1 ATOM 11141 C CG . ASN B 1 649 ? 79.641 78.515 52.177 1.00 51.14 ? 685 ASN B CG 1 ATOM 11142 O OD1 . ASN B 1 649 ? 79.705 77.589 51.363 1.00 52.98 ? 685 ASN B OD1 1 ATOM 11143 N ND2 . ASN B 1 649 ? 80.729 79.084 52.702 1.00 49.95 ? 685 ASN B ND2 1 ATOM 11144 N N . SER B 1 650 ? 76.151 76.809 54.209 1.00 34.58 ? 686 SER B N 1 ATOM 11145 C CA . SER B 1 650 ? 76.165 75.822 55.297 1.00 32.31 ? 686 SER B CA 1 ATOM 11146 C C . SER B 1 650 ? 75.118 74.710 55.174 1.00 33.50 ? 686 SER B C 1 ATOM 11147 O O . SER B 1 650 ? 74.741 74.103 56.182 1.00 32.36 ? 686 SER B O 1 ATOM 11148 C CB . SER B 1 650 ? 76.006 76.524 56.653 1.00 33.41 ? 686 SER B CB 1 ATOM 11149 O OG . SER B 1 650 ? 74.783 77.253 56.713 1.00 33.30 ? 686 SER B OG 1 ATOM 11150 N N . THR B 1 651 ? 74.673 74.427 53.949 1.00 32.48 ? 687 THR B N 1 ATOM 11151 C CA . THR B 1 651 ? 73.692 73.371 53.701 1.00 31.41 ? 687 THR B CA 1 ATOM 11152 C C . THR B 1 651 ? 74.386 72.036 53.465 1.00 31.61 ? 687 THR B C 1 ATOM 11153 O O . THR B 1 651 ? 75.492 71.996 52.924 1.00 31.51 ? 687 THR B O 1 ATOM 11154 C CB . THR B 1 651 ? 72.872 73.653 52.436 1.00 28.60 ? 687 THR B CB 1 ATOM 11155 O OG1 . THR B 1 651 ? 73.714 73.478 51.294 1.00 31.71 ? 687 THR B OG1 1 ATOM 11156 C CG2 . THR B 1 651 ? 72.330 75.060 52.439 1.00 31.95 ? 687 THR B CG2 1 ATOM 11157 N N . VAL B 1 652 ? 73.736 70.943 53.856 1.00 29.09 ? 688 VAL B N 1 ATOM 11158 C CA . VAL B 1 652 ? 74.232 69.610 53.536 1.00 27.93 ? 688 VAL B CA 1 ATOM 11159 C C . VAL B 1 652 ? 74.205 69.356 52.025 1.00 29.36 ? 688 VAL B C 1 ATOM 11160 O O . VAL B 1 652 ? 75.125 68.754 51.487 1.00 29.61 ? 688 VAL B O 1 ATOM 11161 C CB . VAL B 1 652 ? 73.406 68.508 54.219 1.00 31.60 ? 688 VAL B CB 1 ATOM 11162 C CG1 . VAL B 1 652 ? 73.886 67.118 53.761 1.00 27.21 ? 688 VAL B CG1 1 ATOM 11163 C CG2 . VAL B 1 652 ? 73.475 68.644 55.741 1.00 27.57 ? 688 VAL B CG2 1 ATOM 11164 N N . MET B 1 653 ? 73.140 69.804 51.358 1.00 29.68 ? 689 MET B N 1 ATOM 11165 C CA . MET B 1 653 ? 72.945 69.584 49.917 1.00 32.72 ? 689 MET B CA 1 ATOM 11166 C C . MET B 1 653 ? 74.152 69.994 49.066 1.00 34.39 ? 689 MET B C 1 ATOM 11167 O O . MET B 1 653 ? 74.488 69.322 48.101 1.00 36.09 ? 689 MET B O 1 ATOM 11168 C CB . MET B 1 653 ? 71.708 70.337 49.409 1.00 30.15 ? 689 MET B CB 1 ATOM 11169 C CG . MET B 1 653 ? 70.396 69.639 49.682 1.00 30.73 ? 689 MET B CG 1 ATOM 11170 S SD . MET B 1 653 ? 69.941 69.715 51.426 1.00 31.48 ? 689 MET B SD 1 ATOM 11171 C CE . MET B 1 653 ? 69.300 71.373 51.571 1.00 27.09 ? 689 MET B CE 1 ATOM 11172 N N . SER B 1 654 ? 74.805 71.090 49.435 1.00 34.32 ? 690 SER B N 1 ATOM 11173 C CA . SER B 1 654 ? 75.929 71.599 48.658 1.00 35.49 ? 690 SER B CA 1 ATOM 11174 C C . SER B 1 654 ? 77.155 70.667 48.691 1.00 38.35 ? 690 SER B C 1 ATOM 11175 O O . SER B 1 654 ? 78.038 70.769 47.827 1.00 38.98 ? 690 SER B O 1 ATOM 11176 C CB . SER B 1 654 ? 76.307 73.013 49.125 1.00 35.81 ? 690 SER B CB 1 ATOM 11177 O OG . SER B 1 654 ? 76.993 72.975 50.367 1.00 36.59 ? 690 SER B OG 1 ATOM 11178 N N . ARG B 1 655 ? 77.193 69.752 49.663 1.00 30.31 ? 691 ARG B N 1 ATOM 11179 C CA . ARG B 1 655 ? 78.287 68.785 49.777 1.00 30.13 ? 691 ARG B CA 1 ATOM 11180 C C . ARG B 1 655 ? 77.968 67.403 49.188 1.00 33.55 ? 691 ARG B C 1 ATOM 11181 O O . ARG B 1 655 ? 78.707 66.438 49.411 1.00 29.45 ? 691 ARG B O 1 ATOM 11182 C CB . ARG B 1 655 ? 78.689 68.640 51.241 1.00 35.60 ? 691 ARG B CB 1 ATOM 11183 C CG . ARG B 1 655 ? 79.049 69.990 51.872 1.00 36.04 ? 691 ARG B CG 1 ATOM 11184 C CD . ARG B 1 655 ? 79.276 69.910 53.378 1.00 39.10 ? 691 ARG B CD 1 ATOM 11185 N NE . ARG B 1 655 ? 79.869 71.156 53.861 1.00 35.42 ? 691 ARG B NE 1 ATOM 11186 C CZ . ARG B 1 655 ? 80.814 71.228 54.791 1.00 40.46 ? 691 ARG B CZ 1 ATOM 11187 N NH1 . ARG B 1 655 ? 81.282 70.122 55.378 1.00 33.75 ? 691 ARG B NH1 1 ATOM 11188 N NH2 . ARG B 1 655 ? 81.285 72.418 55.141 1.00 40.96 ? 691 ARG B NH2 1 ATOM 11189 N N . ALA B 1 656 ? 76.870 67.314 48.443 1.00 33.72 ? 692 ALA B N 1 ATOM 11190 C CA . ALA B 1 656 ? 76.377 66.027 47.937 1.00 34.37 ? 692 ALA B CA 1 ATOM 11191 C C . ALA B 1 656 ? 77.464 65.155 47.295 1.00 29.84 ? 692 ALA B C 1 ATOM 11192 O O . ALA B 1 656 ? 77.566 63.964 47.595 1.00 28.86 ? 692 ALA B O 1 ATOM 11193 C CB . ALA B 1 656 ? 75.229 66.250 46.968 1.00 28.59 ? 692 ALA B CB 1 ATOM 11194 N N . GLU B 1 657 ? 78.281 65.747 46.429 1.00 33.07 ? 693 GLU B N 1 ATOM 11195 C CA . GLU B 1 657 ? 79.275 64.979 45.663 1.00 34.22 ? 693 GLU B CA 1 ATOM 11196 C C . GLU B 1 657 ? 80.222 64.168 46.536 1.00 38.18 ? 693 GLU B C 1 ATOM 11197 O O . GLU B 1 657 ? 80.601 63.047 46.190 1.00 37.06 ? 693 GLU B O 1 ATOM 11198 C CB . GLU B 1 657 ? 80.101 65.910 44.777 1.00 44.21 ? 693 GLU B CB 1 ATOM 11199 C CG . GLU B 1 657 ? 79.445 66.266 43.466 1.00 48.27 ? 693 GLU B CG 1 ATOM 11200 C CD . GLU B 1 657 ? 79.680 65.213 42.384 1.00 57.00 ? 693 GLU B CD 1 ATOM 11201 O OE1 . GLU B 1 657 ? 80.163 64.098 42.712 1.00 56.82 ? 693 GLU B OE1 1 ATOM 11202 O OE2 . GLU B 1 657 ? 79.383 65.514 41.201 1.00 64.97 ? 693 GLU B OE2 1 ATOM 11203 N N . ASN B 1 658 ? 80.601 64.735 47.676 1.00 35.76 ? 694 ASN B N 1 ATOM 11204 C CA . ASN B 1 658 ? 81.577 64.095 48.545 1.00 34.90 ? 694 ASN B CA 1 ATOM 11205 C C . ASN B 1 658 ? 81.037 62.859 49.248 1.00 34.06 ? 694 ASN B C 1 ATOM 11206 O O . ASN B 1 658 ? 81.797 62.073 49.821 1.00 33.86 ? 694 ASN B O 1 ATOM 11207 C CB . ASN B 1 658 ? 82.129 65.110 49.544 1.00 35.45 ? 694 ASN B CB 1 ATOM 11208 C CG . ASN B 1 658 ? 82.915 66.214 48.860 1.00 37.13 ? 694 ASN B CG 1 ATOM 11209 O OD1 . ASN B 1 658 ? 83.639 65.960 47.899 1.00 43.23 ? 694 ASN B OD1 1 ATOM 11210 N ND2 . ASN B 1 658 ? 82.765 67.443 49.337 1.00 39.23 ? 694 ASN B ND2 1 ATOM 11211 N N . PHE B 1 659 ? 79.723 62.673 49.201 1.00 30.99 ? 695 PHE B N 1 ATOM 11212 C CA . PHE B 1 659 ? 79.135 61.489 49.830 1.00 34.00 ? 695 PHE B CA 1 ATOM 11213 C C . PHE B 1 659 ? 79.470 60.230 49.049 1.00 31.76 ? 695 PHE B C 1 ATOM 11214 O O . PHE B 1 659 ? 79.185 59.117 49.491 1.00 33.05 ? 695 PHE B O 1 ATOM 11215 C CB . PHE B 1 659 ? 77.627 61.628 49.980 1.00 32.40 ? 695 PHE B CB 1 ATOM 11216 C CG . PHE B 1 659 ? 77.217 62.440 51.162 1.00 33.05 ? 695 PHE B CG 1 ATOM 11217 C CD1 . PHE B 1 659 ? 77.288 63.823 51.125 1.00 32.99 ? 695 PHE B CD1 1 ATOM 11218 C CD2 . PHE B 1 659 ? 76.739 61.821 52.307 1.00 29.56 ? 695 PHE B CD2 1 ATOM 11219 C CE1 . PHE B 1 659 ? 76.897 64.580 52.211 1.00 31.93 ? 695 PHE B CE1 1 ATOM 11220 C CE2 . PHE B 1 659 ? 76.353 62.565 53.394 1.00 32.24 ? 695 PHE B CE2 1 ATOM 11221 C CZ . PHE B 1 659 ? 76.432 63.948 53.350 1.00 32.90 ? 695 PHE B CZ 1 ATOM 11222 N N . LYS B 1 660 ? 80.096 60.410 47.894 1.00 33.66 ? 696 LYS B N 1 ATOM 11223 C CA . LYS B 1 660 ? 80.523 59.286 47.079 1.00 33.59 ? 696 LYS B CA 1 ATOM 11224 C C . LYS B 1 660 ? 81.574 58.504 47.833 1.00 34.90 ? 696 LYS B C 1 ATOM 11225 O O . LYS B 1 660 ? 81.758 57.319 47.596 1.00 34.41 ? 696 LYS B O 1 ATOM 11226 C CB . LYS B 1 660 ? 81.102 59.777 45.748 1.00 34.57 ? 696 LYS B CB 1 ATOM 11227 C CG . LYS B 1 660 ? 80.045 59.965 44.671 1.00 44.30 ? 696 LYS B CG 1 ATOM 11228 C CD . LYS B 1 660 ? 80.555 60.743 43.463 1.00 50.83 ? 696 LYS B CD 1 ATOM 11229 C CE . LYS B 1 660 ? 79.414 60.977 42.460 1.00 48.62 ? 696 LYS B CE 1 ATOM 11230 N NZ . LYS B 1 660 ? 79.898 61.564 41.177 1.00 56.31 ? 696 LYS B NZ 1 ATOM 11231 N N . GLN B 1 661 ? 82.261 59.177 48.751 1.00 34.87 ? 697 GLN B N 1 ATOM 11232 C CA . GLN B 1 661 ? 83.379 58.563 49.460 1.00 38.22 ? 697 GLN B CA 1 ATOM 11233 C C . GLN B 1 661 ? 82.966 57.805 50.726 1.00 36.98 ? 697 GLN B C 1 ATOM 11234 O O . GLN B 1 661 ? 83.829 57.306 51.457 1.00 34.60 ? 697 GLN B O 1 ATOM 11235 C CB . GLN B 1 661 ? 84.416 59.628 49.828 1.00 35.80 ? 697 GLN B CB 1 ATOM 11236 C CG . GLN B 1 661 ? 84.824 60.557 48.686 1.00 40.43 ? 697 GLN B CG 1 ATOM 11237 C CD . GLN B 1 661 ? 85.687 61.724 49.172 1.00 46.42 ? 697 GLN B CD 1 ATOM 11238 O OE1 . GLN B 1 661 ? 86.559 61.552 50.032 1.00 50.50 ? 697 GLN B OE1 1 ATOM 11239 N NE2 . GLN B 1 661 ? 85.440 62.915 48.631 1.00 44.76 ? 697 GLN B NE2 1 ATOM 11240 N N . VAL B 1 662 ? 81.664 57.712 51.001 1.00 34.00 ? 698 VAL B N 1 ATOM 11241 C CA . VAL B 1 662 ? 81.228 57.120 52.272 1.00 33.08 ? 698 VAL B CA 1 ATOM 11242 C C . VAL B 1 662 ? 79.930 56.312 52.179 1.00 32.67 ? 698 VAL B C 1 ATOM 11243 O O . VAL B 1 662 ? 79.171 56.445 51.223 1.00 29.08 ? 698 VAL B O 1 ATOM 11244 C CB . VAL B 1 662 ? 81.027 58.211 53.336 1.00 34.59 ? 698 VAL B CB 1 ATOM 11245 C CG1 . VAL B 1 662 ? 82.303 59.017 53.517 1.00 31.35 ? 698 VAL B CG1 1 ATOM 11246 C CG2 . VAL B 1 662 ? 79.875 59.124 52.925 1.00 33.31 ? 698 VAL B CG2 1 ATOM 11247 N N . GLU B 1 663 ? 79.679 55.476 53.185 1.00 31.29 ? 699 GLU B N 1 ATOM 11248 C CA . GLU B 1 663 ? 78.367 54.846 53.335 1.00 36.68 ? 699 GLU B CA 1 ATOM 11249 C C . GLU B 1 663 ? 77.515 55.711 54.257 1.00 30.90 ? 699 GLU B C 1 ATOM 11250 O O . GLU B 1 663 ? 77.899 55.961 55.390 1.00 33.78 ? 699 GLU B O 1 ATOM 11251 C CB . GLU B 1 663 ? 78.484 53.446 53.942 1.00 35.40 ? 699 GLU B CB 1 ATOM 11252 C CG . GLU B 1 663 ? 79.252 52.434 53.120 1.00 46.47 ? 699 GLU B CG 1 ATOM 11253 C CD . GLU B 1 663 ? 79.496 51.151 53.907 1.00 59.85 ? 699 GLU B CD 1 ATOM 11254 O OE1 . GLU B 1 663 ? 78.591 50.748 54.679 1.00 58.49 ? 699 GLU B OE1 1 ATOM 11255 O OE2 . GLU B 1 663 ? 80.594 50.559 53.769 1.00 63.81 ? 699 GLU B OE2 1 ATOM 11256 N N . TYR B 1 664 ? 76.350 56.135 53.783 1.00 27.70 ? 700 TYR B N 1 ATOM 11257 C CA . TYR B 1 664 ? 75.487 57.053 54.531 1.00 27.16 ? 700 TYR B CA 1 ATOM 11258 C C . TYR B 1 664 ? 74.126 56.411 54.749 1.00 28.94 ? 700 TYR B C 1 ATOM 11259 O O . TYR B 1 664 ? 73.517 55.924 53.800 1.00 26.84 ? 700 TYR B O 1 ATOM 11260 C CB . TYR B 1 664 ? 75.334 58.320 53.705 1.00 26.02 ? 700 TYR B CB 1 ATOM 11261 C CG . TYR B 1 664 ? 74.570 59.489 54.294 1.00 28.79 ? 700 TYR B CG 1 ATOM 11262 C CD1 . TYR B 1 664 ? 74.763 59.919 55.619 1.00 26.08 ? 700 TYR B CD1 1 ATOM 11263 C CD2 . TYR B 1 664 ? 73.716 60.220 53.485 1.00 24.33 ? 700 TYR B CD2 1 ATOM 11264 C CE1 . TYR B 1 664 ? 74.073 61.030 56.114 1.00 25.49 ? 700 TYR B CE1 1 ATOM 11265 C CE2 . TYR B 1 664 ? 73.031 61.310 53.953 1.00 25.29 ? 700 TYR B CE2 1 ATOM 11266 C CZ . TYR B 1 664 ? 73.213 61.728 55.261 1.00 29.66 ? 700 TYR B CZ 1 ATOM 11267 O OH . TYR B 1 664 ? 72.504 62.842 55.669 1.00 23.77 ? 700 TYR B OH 1 ATOM 11268 N N . LEU B 1 665 ? 73.658 56.392 55.995 1.00 26.21 ? 701 LEU B N 1 ATOM 11269 C CA . LEU B 1 665 ? 72.278 56.011 56.291 1.00 22.62 ? 701 LEU B CA 1 ATOM 11270 C C . LEU B 1 665 ? 71.517 57.241 56.782 1.00 26.63 ? 701 LEU B C 1 ATOM 11271 O O . LEU B 1 665 ? 71.939 57.906 57.735 1.00 26.30 ? 701 LEU B O 1 ATOM 11272 C CB . LEU B 1 665 ? 72.227 54.903 57.347 1.00 25.22 ? 701 LEU B CB 1 ATOM 11273 C CG . LEU B 1 665 ? 70.845 54.504 57.906 1.00 23.79 ? 701 LEU B CG 1 ATOM 11274 C CD1 . LEU B 1 665 ? 69.887 53.998 56.808 1.00 26.20 ? 701 LEU B CD1 1 ATOM 11275 C CD2 . LEU B 1 665 ? 70.990 53.468 59.000 1.00 24.29 ? 701 LEU B CD2 1 ATOM 11276 N N . LEU B 1 666 ? 70.398 57.530 56.130 1.00 22.48 ? 702 LEU B N 1 ATOM 11277 C CA . LEU B 1 666 ? 69.590 58.708 56.423 1.00 27.60 ? 702 LEU B CA 1 ATOM 11278 C C . LEU B 1 666 ? 68.206 58.273 56.914 1.00 24.42 ? 702 LEU B C 1 ATOM 11279 O O . LEU B 1 666 ? 67.499 57.524 56.236 1.00 25.59 ? 702 LEU B O 1 ATOM 11280 C CB . LEU B 1 666 ? 69.460 59.562 55.153 1.00 19.91 ? 702 LEU B CB 1 ATOM 11281 C CG . LEU B 1 666 ? 68.569 60.800 55.225 1.00 24.17 ? 702 LEU B CG 1 ATOM 11282 C CD1 . LEU B 1 666 ? 69.154 61.843 56.182 1.00 25.74 ? 702 LEU B CD1 1 ATOM 11283 C CD2 . LEU B 1 666 ? 68.434 61.386 53.845 1.00 23.83 ? 702 LEU B CD2 1 ATOM 11284 N N . ILE B 1 667 ? 67.806 58.752 58.083 1.00 22.78 ? 703 ILE B N 1 ATOM 11285 C CA . ILE B 1 667 ? 66.585 58.271 58.732 1.00 20.86 ? 703 ILE B CA 1 ATOM 11286 C C . ILE B 1 667 ? 65.753 59.461 59.198 1.00 25.49 ? 703 ILE B C 1 ATOM 11287 O O . ILE B 1 667 ? 66.295 60.413 59.756 1.00 23.94 ? 703 ILE B O 1 ATOM 11288 C CB . ILE B 1 667 ? 66.935 57.365 59.932 1.00 21.86 ? 703 ILE B CB 1 ATOM 11289 C CG1 . ILE B 1 667 ? 67.841 56.217 59.501 1.00 23.72 ? 703 ILE B CG1 1 ATOM 11290 C CG2 . ILE B 1 667 ? 65.679 56.814 60.609 1.00 21.79 ? 703 ILE B CG2 1 ATOM 11291 C CD1 . ILE B 1 667 ? 68.338 55.339 60.665 1.00 20.80 ? 703 ILE B CD1 1 ATOM 11292 N N . HIS B 1 668 ? 64.442 59.418 58.983 1.00 24.39 ? 704 HIS B N 1 ATOM 11293 C CA . HIS B 1 668 ? 63.586 60.541 59.368 1.00 22.94 ? 704 HIS B CA 1 ATOM 11294 C C . HIS B 1 668 ? 62.130 60.100 59.602 1.00 26.00 ? 704 HIS B C 1 ATOM 11295 O O . HIS B 1 668 ? 61.607 59.285 58.845 1.00 27.99 ? 704 HIS B O 1 ATOM 11296 C CB . HIS B 1 668 ? 63.663 61.665 58.318 1.00 20.57 ? 704 HIS B CB 1 ATOM 11297 C CG . HIS B 1 668 ? 63.527 63.046 58.893 1.00 24.41 ? 704 HIS B CG 1 ATOM 11298 N ND1 . HIS B 1 668 ? 64.433 64.054 58.637 1.00 23.09 ? 704 HIS B ND1 1 ATOM 11299 C CD2 . HIS B 1 668 ? 62.589 63.583 59.713 1.00 24.69 ? 704 HIS B CD2 1 ATOM 11300 C CE1 . HIS B 1 668 ? 64.064 65.152 59.275 1.00 22.54 ? 704 HIS B CE1 1 ATOM 11301 N NE2 . HIS B 1 668 ? 62.947 64.893 59.938 1.00 23.67 ? 704 HIS B NE2 1 ATOM 11302 N N . GLY B 1 669 ? 61.489 60.628 60.648 1.00 20.94 ? 705 GLY B N 1 ATOM 11303 C CA . GLY B 1 669 ? 60.074 60.377 60.891 1.00 20.00 ? 705 GLY B CA 1 ATOM 11304 C C . GLY B 1 669 ? 59.218 61.248 59.974 1.00 24.61 ? 705 GLY B C 1 ATOM 11305 O O . GLY B 1 669 ? 59.504 62.439 59.823 1.00 26.40 ? 705 GLY B O 1 ATOM 11306 N N . THR B 1 670 ? 58.181 60.684 59.350 1.00 22.15 ? 706 THR B N 1 ATOM 11307 C CA . THR B 1 670 ? 57.358 61.460 58.400 1.00 24.18 ? 706 THR B CA 1 ATOM 11308 C C . THR B 1 670 ? 56.470 62.533 59.063 1.00 26.27 ? 706 THR B C 1 ATOM 11309 O O . THR B 1 670 ? 56.074 63.511 58.413 1.00 24.58 ? 706 THR B O 1 ATOM 11310 C CB . THR B 1 670 ? 56.464 60.559 57.499 1.00 26.24 ? 706 THR B CB 1 ATOM 11311 O OG1 . THR B 1 670 ? 55.557 59.810 58.316 1.00 26.37 ? 706 THR B OG1 1 ATOM 11312 C CG2 . THR B 1 670 ? 57.320 59.593 56.686 1.00 26.26 ? 706 THR B CG2 1 ATOM 11313 N N . ALA B 1 671 ? 56.170 62.343 60.345 1.00 23.63 ? 707 ALA B N 1 ATOM 11314 C CA . ALA B 1 671 ? 55.376 63.309 61.116 1.00 27.26 ? 707 ALA B CA 1 ATOM 11315 C C . ALA B 1 671 ? 56.220 64.161 62.052 1.00 25.51 ? 707 ALA B C 1 ATOM 11316 O O . ALA B 1 671 ? 55.778 64.508 63.143 1.00 27.74 ? 707 ALA B O 1 ATOM 11317 C CB . ALA B 1 671 ? 54.301 62.587 61.924 1.00 24.04 ? 707 ALA B CB 1 ATOM 11318 N N . ASP B 1 672 ? 57.430 64.500 61.633 1.00 23.44 ? 708 ASP B N 1 ATOM 11319 C CA . ASP B 1 672 ? 58.318 65.308 62.457 1.00 24.53 ? 708 ASP B CA 1 ATOM 11320 C C . ASP B 1 672 ? 57.848 66.743 62.326 1.00 24.50 ? 708 ASP B C 1 ATOM 11321 O O . ASP B 1 672 ? 57.995 67.364 61.276 1.00 23.82 ? 708 ASP B O 1 ATOM 11322 C CB . ASP B 1 672 ? 59.764 65.142 61.971 1.00 24.75 ? 708 ASP B CB 1 ATOM 11323 C CG . ASP B 1 672 ? 60.791 65.637 62.972 1.00 24.65 ? 708 ASP B CG 1 ATOM 11324 O OD1 . ASP B 1 672 ? 60.491 66.614 63.698 1.00 26.07 ? 708 ASP B OD1 1 ATOM 11325 O OD2 . ASP B 1 672 ? 61.907 65.057 63.019 1.00 21.66 ? 708 ASP B OD2 1 ATOM 11326 N N . ASP B 1 673 ? 57.248 67.252 63.394 1.00 25.26 ? 709 ASP B N 1 ATOM 11327 C CA . ASP B 1 673 ? 56.697 68.602 63.427 1.00 24.78 ? 709 ASP B CA 1 ATOM 11328 C C . ASP B 1 673 ? 57.794 69.596 63.741 1.00 23.31 ? 709 ASP B C 1 ATOM 11329 O O . ASP B 1 673 ? 57.566 70.808 63.711 1.00 21.60 ? 709 ASP B O 1 ATOM 11330 C CB . ASP B 1 673 ? 55.657 68.701 64.552 1.00 25.10 ? 709 ASP B CB 1 ATOM 11331 C CG . ASP B 1 673 ? 56.248 68.365 65.926 1.00 26.41 ? 709 ASP B CG 1 ATOM 11332 O OD1 . ASP B 1 673 ? 56.411 67.163 66.229 1.00 27.17 ? 709 ASP B OD1 1 ATOM 11333 O OD2 . ASP B 1 673 ? 56.556 69.298 66.707 1.00 27.31 ? 709 ASP B OD2 1 ATOM 11334 N N . ASN B 1 674 ? 58.964 69.072 64.097 1.00 23.33 ? 710 ASN B N 1 ATOM 11335 C CA . ASN B 1 674 ? 60.069 69.879 64.636 1.00 24.31 ? 710 ASN B CA 1 ATOM 11336 C C . ASN B 1 674 ? 61.169 70.125 63.584 1.00 22.39 ? 710 ASN B C 1 ATOM 11337 O O . ASN B 1 674 ? 61.338 71.241 63.077 1.00 24.54 ? 710 ASN B O 1 ATOM 11338 C CB . ASN B 1 674 ? 60.648 69.184 65.880 1.00 23.06 ? 710 ASN B CB 1 ATOM 11339 C CG . ASN B 1 674 ? 61.519 70.115 66.729 1.00 26.25 ? 710 ASN B CG 1 ATOM 11340 O OD1 . ASN B 1 674 ? 62.160 71.040 66.212 1.00 26.84 ? 710 ASN B OD1 1 ATOM 11341 N ND2 . ASN B 1 674 ? 61.546 69.866 68.034 1.00 24.63 ? 710 ASN B ND2 1 ATOM 11342 N N . VAL B 1 675 ? 61.910 69.076 63.254 1.00 20.16 ? 711 VAL B N 1 ATOM 11343 C CA . VAL B 1 675 ? 62.792 69.117 62.086 1.00 23.77 ? 711 VAL B CA 1 ATOM 11344 C C . VAL B 1 675 ? 61.997 68.419 60.996 1.00 24.55 ? 711 VAL B C 1 ATOM 11345 O O . VAL B 1 675 ? 61.811 67.209 61.021 1.00 22.76 ? 711 VAL B O 1 ATOM 11346 C CB . VAL B 1 675 ? 64.124 68.382 62.340 1.00 24.98 ? 711 VAL B CB 1 ATOM 11347 C CG1 . VAL B 1 675 ? 65.009 68.376 61.076 1.00 20.76 ? 711 VAL B CG1 1 ATOM 11348 C CG2 . VAL B 1 675 ? 64.867 69.020 63.510 1.00 24.83 ? 711 VAL B CG2 1 ATOM 11349 N N . HIS B 1 676 ? 61.474 69.189 60.062 1.00 22.06 ? 712 HIS B N 1 ATOM 11350 C CA . HIS B 1 676 ? 60.495 68.649 59.133 1.00 23.10 ? 712 HIS B CA 1 ATOM 11351 C C . HIS B 1 676 ? 61.101 67.590 58.202 1.00 26.21 ? 712 HIS B C 1 ATOM 11352 O O . HIS B 1 676 ? 62.268 67.683 57.812 1.00 22.22 ? 712 HIS B O 1 ATOM 11353 C CB . HIS B 1 676 ? 59.848 69.801 58.354 1.00 23.31 ? 712 HIS B CB 1 ATOM 11354 C CG . HIS B 1 676 ? 59.166 70.788 59.247 1.00 25.20 ? 712 HIS B CG 1 ATOM 11355 N ND1 . HIS B 1 676 ? 59.183 72.147 59.020 1.00 27.63 ? 712 HIS B ND1 1 ATOM 11356 C CD2 . HIS B 1 676 ? 58.485 70.607 60.402 1.00 25.33 ? 712 HIS B CD2 1 ATOM 11357 C CE1 . HIS B 1 676 ? 58.522 72.757 59.987 1.00 25.79 ? 712 HIS B CE1 1 ATOM 11358 N NE2 . HIS B 1 676 ? 58.092 71.846 60.840 1.00 25.56 ? 712 HIS B NE2 1 ATOM 11359 N N . PHE B 1 677 ? 60.308 66.576 57.866 1.00 22.25 ? 713 PHE B N 1 ATOM 11360 C CA . PHE B 1 677 ? 60.749 65.571 56.910 1.00 21.81 ? 713 PHE B CA 1 ATOM 11361 C C . PHE B 1 677 ? 61.353 66.247 55.689 1.00 22.95 ? 713 PHE B C 1 ATOM 11362 O O . PHE B 1 677 ? 62.330 65.766 55.127 1.00 25.90 ? 713 PHE B O 1 ATOM 11363 C CB . PHE B 1 677 ? 59.590 64.671 56.484 1.00 22.39 ? 713 PHE B CB 1 ATOM 11364 C CG . PHE B 1 677 ? 60.032 63.488 55.680 1.00 21.39 ? 713 PHE B CG 1 ATOM 11365 C CD1 . PHE B 1 677 ? 60.611 62.399 56.303 1.00 23.47 ? 713 PHE B CD1 1 ATOM 11366 C CD2 . PHE B 1 677 ? 59.903 63.479 54.305 1.00 25.86 ? 713 PHE B CD2 1 ATOM 11367 C CE1 . PHE B 1 677 ? 61.041 61.303 55.565 1.00 27.21 ? 713 PHE B CE1 1 ATOM 11368 C CE2 . PHE B 1 677 ? 60.334 62.390 53.563 1.00 24.45 ? 713 PHE B CE2 1 ATOM 11369 C CZ . PHE B 1 677 ? 60.905 61.302 54.210 1.00 21.89 ? 713 PHE B CZ 1 ATOM 11370 N N . GLN B 1 678 ? 60.760 67.367 55.286 1.00 24.23 ? 714 GLN B N 1 ATOM 11371 C CA . GLN B 1 678 ? 61.305 68.219 54.231 1.00 23.42 ? 714 GLN B CA 1 ATOM 11372 C C . GLN B 1 678 ? 62.826 68.231 54.221 1.00 27.66 ? 714 GLN B C 1 ATOM 11373 O O . GLN B 1 678 ? 63.451 68.060 53.172 1.00 26.05 ? 714 GLN B O 1 ATOM 11374 C CB . GLN B 1 678 ? 60.791 69.658 54.404 1.00 24.83 ? 714 GLN B CB 1 ATOM 11375 C CG . GLN B 1 678 ? 61.473 70.686 53.494 1.00 23.49 ? 714 GLN B CG 1 ATOM 11376 C CD . GLN B 1 678 ? 61.209 72.110 53.936 1.00 26.05 ? 714 GLN B CD 1 ATOM 11377 O OE1 . GLN B 1 678 ? 61.053 72.374 55.133 1.00 27.82 ? 714 GLN B OE1 1 ATOM 11378 N NE2 . GLN B 1 678 ? 61.144 73.038 52.982 1.00 24.58 ? 714 GLN B NE2 1 ATOM 11379 N N . GLN B 1 679 ? 63.424 68.422 55.399 1.00 26.20 ? 715 GLN B N 1 ATOM 11380 C CA . GLN B 1 679 ? 64.869 68.570 55.498 1.00 24.00 ? 715 GLN B CA 1 ATOM 11381 C C . GLN B 1 679 ? 65.631 67.346 54.951 1.00 27.39 ? 715 GLN B C 1 ATOM 11382 O O . GLN B 1 679 ? 66.609 67.501 54.225 1.00 25.52 ? 715 GLN B O 1 ATOM 11383 C CB . GLN B 1 679 ? 65.277 68.874 56.949 1.00 27.55 ? 715 GLN B CB 1 ATOM 11384 C CG . GLN B 1 679 ? 64.502 70.029 57.591 1.00 21.85 ? 715 GLN B CG 1 ATOM 11385 C CD . GLN B 1 679 ? 65.432 71.070 58.196 1.00 25.29 ? 715 GLN B CD 1 ATOM 11386 O OE1 . GLN B 1 679 ? 66.572 71.227 57.755 1.00 25.63 ? 715 GLN B OE1 1 ATOM 11387 N NE2 . GLN B 1 679 ? 64.950 71.785 59.204 1.00 22.59 ? 715 GLN B NE2 1 ATOM 11388 N N . SER B 1 680 ? 65.210 66.136 55.310 1.00 24.55 ? 716 SER B N 1 ATOM 11389 C CA . SER B 1 680 ? 65.856 64.946 54.759 1.00 23.89 ? 716 SER B CA 1 ATOM 11390 C C . SER B 1 680 ? 65.419 64.697 53.315 1.00 25.73 ? 716 SER B C 1 ATOM 11391 O O . SER B 1 680 ? 66.168 64.116 52.521 1.00 24.66 ? 716 SER B O 1 ATOM 11392 C CB . SER B 1 680 ? 65.550 63.704 55.587 1.00 24.20 ? 716 SER B CB 1 ATOM 11393 O OG . SER B 1 680 ? 66.355 63.649 56.740 1.00 24.07 ? 716 SER B OG 1 ATOM 11394 N N . ALA B 1 681 ? 64.211 65.133 52.981 1.00 22.37 ? 717 ALA B N 1 ATOM 11395 C CA . ALA B 1 681 ? 63.709 64.967 51.623 1.00 25.35 ? 717 ALA B CA 1 ATOM 11396 C C . ALA B 1 681 ? 64.602 65.742 50.656 1.00 27.16 ? 717 ALA B C 1 ATOM 11397 O O . ALA B 1 681 ? 64.843 65.306 49.535 1.00 22.33 ? 717 ALA B O 1 ATOM 11398 C CB . ALA B 1 681 ? 62.273 65.444 51.525 1.00 23.14 ? 717 ALA B CB 1 ATOM 11399 N N . GLN B 1 682 ? 65.099 66.893 51.094 1.00 22.50 ? 718 GLN B N 1 ATOM 11400 C CA . GLN B 1 682 ? 65.975 67.699 50.248 1.00 23.49 ? 718 GLN B CA 1 ATOM 11401 C C . GLN B 1 682 ? 67.392 67.105 50.208 1.00 26.20 ? 718 GLN B C 1 ATOM 11402 O O . GLN B 1 682 ? 68.072 67.203 49.192 1.00 26.74 ? 718 GLN B O 1 ATOM 11403 C CB . GLN B 1 682 ? 66.000 69.164 50.710 1.00 21.45 ? 718 GLN B CB 1 ATOM 11404 C CG . GLN B 1 682 ? 64.662 69.898 50.559 1.00 22.93 ? 718 GLN B CG 1 ATOM 11405 C CD . GLN B 1 682 ? 64.317 70.190 49.098 1.00 26.88 ? 718 GLN B CD 1 ATOM 11406 O OE1 . GLN B 1 682 ? 65.024 69.774 48.190 1.00 28.83 ? 718 GLN B OE1 1 ATOM 11407 N NE2 . GLN B 1 682 ? 63.230 70.899 48.876 1.00 29.47 ? 718 GLN B NE2 1 ATOM 11408 N N . ILE B 1 683 ? 67.838 66.485 51.302 1.00 24.92 ? 719 ILE B N 1 ATOM 11409 C CA . ILE B 1 683 ? 69.122 65.784 51.286 1.00 22.38 ? 719 ILE B CA 1 ATOM 11410 C C . ILE B 1 683 ? 69.109 64.650 50.268 1.00 26.54 ? 719 ILE B C 1 ATOM 11411 O O . ILE B 1 683 ? 70.019 64.547 49.456 1.00 27.89 ? 719 ILE B O 1 ATOM 11412 C CB . ILE B 1 683 ? 69.520 65.163 52.648 1.00 24.41 ? 719 ILE B CB 1 ATOM 11413 C CG1 . ILE B 1 683 ? 69.875 66.237 53.686 1.00 24.45 ? 719 ILE B CG1 1 ATOM 11414 C CG2 . ILE B 1 683 ? 70.718 64.257 52.467 1.00 24.55 ? 719 ILE B CG2 1 ATOM 11415 C CD1 . ILE B 1 683 ? 70.104 65.669 55.085 1.00 20.92 ? 719 ILE B CD1 1 ATOM 11416 N N . SER B 1 684 ? 68.105 63.778 50.317 1.00 23.07 ? 720 SER B N 1 ATOM 11417 C CA . SER B 1 684 ? 68.095 62.618 49.405 1.00 26.29 ? 720 SER B CA 1 ATOM 11418 C C . SER B 1 684 ? 68.042 63.031 47.936 1.00 25.66 ? 720 SER B C 1 ATOM 11419 O O . SER B 1 684 ? 68.669 62.393 47.086 1.00 26.69 ? 720 SER B O 1 ATOM 11420 C CB . SER B 1 684 ? 66.929 61.674 49.704 1.00 24.14 ? 720 SER B CB 1 ATOM 11421 O OG . SER B 1 684 ? 65.701 62.362 49.569 1.00 23.70 ? 720 SER B OG 1 ATOM 11422 N N . LYS B 1 685 ? 67.273 64.079 47.639 1.00 24.78 ? 721 LYS B N 1 ATOM 11423 C CA . LYS B 1 685 ? 67.145 64.568 46.271 1.00 27.96 ? 721 LYS B CA 1 ATOM 11424 C C . LYS B 1 685 ? 68.471 65.114 45.739 1.00 31.12 ? 721 LYS B C 1 ATOM 11425 O O . LYS B 1 685 ? 68.799 64.905 44.578 1.00 29.41 ? 721 LYS B O 1 ATOM 11426 C CB . LYS B 1 685 ? 66.044 65.621 46.165 1.00 26.90 ? 721 LYS B CB 1 ATOM 11427 C CG . LYS B 1 685 ? 65.902 66.237 44.771 1.00 30.20 ? 721 LYS B CG 1 ATOM 11428 C CD . LYS B 1 685 ? 64.484 66.716 44.524 1.00 29.89 ? 721 LYS B CD 1 ATOM 11429 C CE . LYS B 1 685 ? 64.077 67.809 45.505 1.00 32.25 ? 721 LYS B CE 1 ATOM 11430 N NZ . LYS B 1 685 ? 64.748 69.122 45.249 1.00 34.45 ? 721 LYS B NZ 1 ATOM 11431 N N . ALA B 1 686 ? 69.244 65.789 46.591 1.00 27.74 ? 722 ALA B N 1 ATOM 11432 C CA . ALA B 1 686 ? 70.570 66.268 46.195 1.00 30.61 ? 722 ALA B CA 1 ATOM 11433 C C . ALA B 1 686 ? 71.522 65.104 45.930 1.00 30.15 ? 722 ALA B C 1 ATOM 11434 O O . ALA B 1 686 ? 72.317 65.147 44.994 1.00 31.85 ? 722 ALA B O 1 ATOM 11435 C CB . ALA B 1 686 ? 71.153 67.203 47.262 1.00 26.81 ? 722 ALA B CB 1 ATOM 11436 N N . LEU B 1 687 ? 71.451 64.065 46.757 1.00 25.61 ? 723 LEU B N 1 ATOM 11437 C CA . LEU B 1 687 ? 72.266 62.863 46.552 1.00 24.57 ? 723 LEU B CA 1 ATOM 11438 C C . LEU B 1 687 ? 71.867 62.145 45.250 1.00 31.97 ? 723 LEU B C 1 ATOM 11439 O O . LEU B 1 687 ? 72.726 61.723 44.469 1.00 28.47 ? 723 LEU B O 1 ATOM 11440 C CB . LEU B 1 687 ? 72.138 61.921 47.753 1.00 24.85 ? 723 LEU B CB 1 ATOM 11441 C CG . LEU B 1 687 ? 72.659 62.489 49.094 1.00 28.57 ? 723 LEU B CG 1 ATOM 11442 C CD1 . LEU B 1 687 ? 72.530 61.488 50.246 1.00 27.47 ? 723 LEU B CD1 1 ATOM 11443 C CD2 . LEU B 1 687 ? 74.093 62.890 48.945 1.00 28.62 ? 723 LEU B CD2 1 ATOM 11444 N N . VAL B 1 688 ? 70.562 62.016 45.016 1.00 29.79 ? 724 VAL B N 1 ATOM 11445 C CA . VAL B 1 688 ? 70.075 61.381 43.796 1.00 28.17 ? 724 VAL B CA 1 ATOM 11446 C C . VAL B 1 688 ? 70.499 62.179 42.561 1.00 31.43 ? 724 VAL B C 1 ATOM 11447 O O . VAL B 1 688 ? 70.904 61.603 41.555 1.00 29.58 ? 724 VAL B O 1 ATOM 11448 C CB . VAL B 1 688 ? 68.546 61.231 43.762 1.00 29.04 ? 724 VAL B CB 1 ATOM 11449 C CG1 . VAL B 1 688 ? 68.116 60.728 42.377 1.00 28.08 ? 724 VAL B CG1 1 ATOM 11450 C CG2 . VAL B 1 688 ? 68.063 60.270 44.862 1.00 28.78 ? 724 VAL B CG2 1 ATOM 11451 N N . ASP B 1 689 ? 70.398 63.501 42.636 1.00 29.64 ? 725 ASP B N 1 ATOM 11452 C CA . ASP B 1 689 ? 70.719 64.352 41.487 1.00 32.43 ? 725 ASP B CA 1 ATOM 11453 C C . ASP B 1 689 ? 72.183 64.229 41.058 1.00 34.24 ? 725 ASP B C 1 ATOM 11454 O O . ASP B 1 689 ? 72.528 64.505 39.909 1.00 39.29 ? 725 ASP B O 1 ATOM 11455 C CB . ASP B 1 689 ? 70.361 65.823 41.759 1.00 35.38 ? 725 ASP B CB 1 ATOM 11456 C CG . ASP B 1 689 ? 68.859 66.102 41.628 1.00 44.99 ? 725 ASP B CG 1 ATOM 11457 O OD1 . ASP B 1 689 ? 68.077 65.137 41.428 1.00 46.65 ? 725 ASP B OD1 1 ATOM 11458 O OD2 . ASP B 1 689 ? 68.454 67.287 41.734 1.00 50.36 ? 725 ASP B OD2 1 ATOM 11459 N N . VAL B 1 690 ? 73.040 63.798 41.973 1.00 31.22 ? 726 VAL B N 1 ATOM 11460 C CA . VAL B 1 690 ? 74.464 63.706 41.680 1.00 34.70 ? 726 VAL B CA 1 ATOM 11461 C C . VAL B 1 690 ? 74.958 62.254 41.624 1.00 34.55 ? 726 VAL B C 1 ATOM 11462 O O . VAL B 1 690 ? 76.160 61.992 41.666 1.00 38.28 ? 726 VAL B O 1 ATOM 11463 C CB . VAL B 1 690 ? 75.281 64.528 42.709 1.00 41.01 ? 726 VAL B CB 1 ATOM 11464 C CG1 . VAL B 1 690 ? 75.474 63.743 44.000 1.00 33.70 ? 726 VAL B CG1 1 ATOM 11465 C CG2 . VAL B 1 690 ? 76.599 64.930 42.132 1.00 46.07 ? 726 VAL B CG2 1 ATOM 11466 N N . GLY B 1 691 ? 74.025 61.311 41.525 1.00 33.44 ? 727 GLY B N 1 ATOM 11467 C CA . GLY B 1 691 ? 74.365 59.903 41.395 1.00 29.15 ? 727 GLY B CA 1 ATOM 11468 C C . GLY B 1 691 ? 75.085 59.275 42.586 1.00 33.57 ? 727 GLY B C 1 ATOM 11469 O O . GLY B 1 691 ? 75.920 58.386 42.412 1.00 30.45 ? 727 GLY B O 1 ATOM 11470 N N . VAL B 1 692 ? 74.785 59.727 43.801 1.00 32.85 ? 728 VAL B N 1 ATOM 11471 C CA . VAL B 1 692 ? 75.376 59.105 44.991 1.00 28.30 ? 728 VAL B CA 1 ATOM 11472 C C . VAL B 1 692 ? 74.449 58.018 45.551 1.00 31.75 ? 728 VAL B C 1 ATOM 11473 O O . VAL B 1 692 ? 73.277 58.276 45.810 1.00 31.16 ? 728 VAL B O 1 ATOM 11474 C CB . VAL B 1 692 ? 75.687 60.154 46.107 1.00 31.05 ? 728 VAL B CB 1 ATOM 11475 C CG1 . VAL B 1 692 ? 76.180 59.460 47.377 1.00 32.67 ? 728 VAL B CG1 1 ATOM 11476 C CG2 . VAL B 1 692 ? 76.727 61.145 45.636 1.00 36.49 ? 728 VAL B CG2 1 ATOM 11477 N N . ASP B 1 693 ? 74.959 56.807 45.753 1.00 26.89 ? 729 ASP B N 1 ATOM 11478 C CA . ASP B 1 693 ? 74.144 55.781 46.385 1.00 32.73 ? 729 ASP B CA 1 ATOM 11479 C C . ASP B 1 693 ? 74.189 55.950 47.893 1.00 31.93 ? 729 ASP B C 1 ATOM 11480 O O . ASP B 1 693 ? 75.213 56.304 48.455 1.00 33.05 ? 729 ASP B O 1 ATOM 11481 C CB . ASP B 1 693 ? 74.608 54.369 46.025 1.00 37.33 ? 729 ASP B CB 1 ATOM 11482 C CG . ASP B 1 693 ? 73.553 53.313 46.355 1.00 41.33 ? 729 ASP B CG 1 ATOM 11483 O OD1 . ASP B 1 693 ? 72.348 53.621 46.186 1.00 37.32 ? 729 ASP B OD1 1 ATOM 11484 O OD2 . ASP B 1 693 ? 73.916 52.194 46.798 1.00 40.75 ? 729 ASP B OD2 1 ATOM 11485 N N . PHE B 1 694 ? 73.072 55.683 48.546 1.00 32.62 ? 730 PHE B N 1 ATOM 11486 C CA . PHE B 1 694 ? 73.022 55.743 49.995 1.00 28.41 ? 730 PHE B CA 1 ATOM 11487 C C . PHE B 1 694 ? 71.889 54.859 50.485 1.00 29.00 ? 730 PHE B C 1 ATOM 11488 O O . PHE B 1 694 ? 71.163 54.261 49.682 1.00 30.35 ? 730 PHE B O 1 ATOM 11489 C CB . PHE B 1 694 ? 72.833 57.192 50.460 1.00 24.99 ? 730 PHE B CB 1 ATOM 11490 C CG . PHE B 1 694 ? 71.568 57.825 49.966 1.00 26.03 ? 730 PHE B CG 1 ATOM 11491 C CD1 . PHE B 1 694 ? 71.484 58.324 48.683 1.00 29.80 ? 730 PHE B CD1 1 ATOM 11492 C CD2 . PHE B 1 694 ? 70.461 57.915 50.782 1.00 27.61 ? 730 PHE B CD2 1 ATOM 11493 C CE1 . PHE B 1 694 ? 70.310 58.911 48.212 1.00 27.31 ? 730 PHE B CE1 1 ATOM 11494 C CE2 . PHE B 1 694 ? 69.281 58.497 50.321 1.00 25.80 ? 730 PHE B CE2 1 ATOM 11495 C CZ . PHE B 1 694 ? 69.203 58.990 49.034 1.00 28.85 ? 730 PHE B CZ 1 ATOM 11496 N N . GLN B 1 695 ? 71.744 54.768 51.803 1.00 26.13 ? 731 GLN B N 1 ATOM 11497 C CA . GLN B 1 695 ? 70.672 53.990 52.405 1.00 26.63 ? 731 GLN B CA 1 ATOM 11498 C C . GLN B 1 695 ? 69.750 54.937 53.151 1.00 31.09 ? 731 GLN B C 1 ATOM 11499 O O . GLN B 1 695 ? 70.198 55.973 53.657 1.00 26.93 ? 731 GLN B O 1 ATOM 11500 C CB . GLN B 1 695 ? 71.268 52.976 53.369 1.00 28.75 ? 731 GLN B CB 1 ATOM 11501 C CG . GLN B 1 695 ? 72.386 52.168 52.760 1.00 39.87 ? 731 GLN B CG 1 ATOM 11502 C CD . GLN B 1 695 ? 72.003 50.718 52.631 1.00 52.47 ? 731 GLN B CD 1 ATOM 11503 O OE1 . GLN B 1 695 ? 71.502 50.292 51.588 1.00 51.80 ? 731 GLN B OE1 1 ATOM 11504 N NE2 . GLN B 1 695 ? 72.208 49.949 53.706 1.00 49.58 ? 731 GLN B NE2 1 ATOM 11505 N N . ALA B 1 696 ? 68.472 54.578 53.242 1.00 27.67 ? 732 ALA B N 1 ATOM 11506 C CA . ALA B 1 696 ? 67.480 55.463 53.834 1.00 25.48 ? 732 ALA B CA 1 ATOM 11507 C C . ALA B 1 696 ? 66.427 54.660 54.580 1.00 28.03 ? 732 ALA B C 1 ATOM 11508 O O . ALA B 1 696 ? 66.249 53.477 54.330 1.00 26.61 ? 732 ALA B O 1 ATOM 11509 C CB . ALA B 1 696 ? 66.817 56.310 52.751 1.00 26.41 ? 732 ALA B CB 1 ATOM 11510 N N . MET B 1 697 ? 65.720 55.315 55.489 1.00 25.35 ? 733 MET B N 1 ATOM 11511 C CA . MET B 1 697 ? 64.593 54.702 56.183 1.00 26.30 ? 733 MET B CA 1 ATOM 11512 C C . MET B 1 697 ? 63.679 55.828 56.658 1.00 27.23 ? 733 MET B C 1 ATOM 11513 O O . MET B 1 697 ? 64.119 56.721 57.382 1.00 26.30 ? 733 MET B O 1 ATOM 11514 C CB . MET B 1 697 ? 65.088 53.867 57.379 1.00 22.63 ? 733 MET B CB 1 ATOM 11515 C CG . MET B 1 697 ? 63.978 53.249 58.217 1.00 25.30 ? 733 MET B CG 1 ATOM 11516 S SD . MET B 1 697 ? 62.953 52.059 57.301 1.00 30.61 ? 733 MET B SD 1 ATOM 11517 C CE . MET B 1 697 ? 64.181 50.823 56.872 1.00 28.09 ? 733 MET B CE 1 ATOM 11518 N N . TRP B 1 698 ? 62.423 55.830 56.218 1.00 24.92 ? 734 TRP B N 1 ATOM 11519 C CA . TRP B 1 698 ? 61.448 56.743 56.804 1.00 24.86 ? 734 TRP B CA 1 ATOM 11520 C C . TRP B 1 698 ? 60.713 55.995 57.906 1.00 25.67 ? 734 TRP B C 1 ATOM 11521 O O . TRP B 1 698 ? 60.649 54.768 57.876 1.00 25.12 ? 734 TRP B O 1 ATOM 11522 C CB . TRP B 1 698 ? 60.447 57.252 55.757 1.00 24.67 ? 734 TRP B CB 1 ATOM 11523 C CG . TRP B 1 698 ? 59.435 56.209 55.343 1.00 25.92 ? 734 TRP B CG 1 ATOM 11524 C CD1 . TRP B 1 698 ? 58.308 55.838 56.021 1.00 24.89 ? 734 TRP B CD1 1 ATOM 11525 C CD2 . TRP B 1 698 ? 59.466 55.416 54.151 1.00 23.76 ? 734 TRP B CD2 1 ATOM 11526 N NE1 . TRP B 1 698 ? 57.636 54.858 55.322 1.00 25.51 ? 734 TRP B NE1 1 ATOM 11527 C CE2 . TRP B 1 698 ? 58.325 54.584 54.170 1.00 24.91 ? 734 TRP B CE2 1 ATOM 11528 C CE3 . TRP B 1 698 ? 60.346 55.332 53.069 1.00 23.22 ? 734 TRP B CE3 1 ATOM 11529 C CZ2 . TRP B 1 698 ? 58.049 53.673 53.153 1.00 24.20 ? 734 TRP B CZ2 1 ATOM 11530 C CZ3 . TRP B 1 698 ? 60.069 54.423 52.059 1.00 23.64 ? 734 TRP B CZ3 1 ATOM 11531 C CH2 . TRP B 1 698 ? 58.929 53.609 52.108 1.00 24.48 ? 734 TRP B CH2 1 ATOM 11532 N N . TYR B 1 699 ? 60.160 56.722 58.875 1.00 25.52 ? 735 TYR B N 1 ATOM 11533 C CA . TYR B 1 699 ? 59.332 56.106 59.912 1.00 26.74 ? 735 TYR B CA 1 ATOM 11534 C C . TYR B 1 699 ? 57.935 56.722 59.881 1.00 27.20 ? 735 TYR B C 1 ATOM 11535 O O . TYR B 1 699 ? 57.733 57.836 60.342 1.00 25.50 ? 735 TYR B O 1 ATOM 11536 C CB . TYR B 1 699 ? 60.006 56.191 61.310 1.00 25.59 ? 735 TYR B CB 1 ATOM 11537 C CG . TYR B 1 699 ? 61.056 55.101 61.471 1.00 25.02 ? 735 TYR B CG 1 ATOM 11538 C CD1 . TYR B 1 699 ? 60.684 53.794 61.768 1.00 23.05 ? 735 TYR B CD1 1 ATOM 11539 C CD2 . TYR B 1 699 ? 62.405 55.364 61.269 1.00 24.88 ? 735 TYR B CD2 1 ATOM 11540 C CE1 . TYR B 1 699 ? 61.623 52.780 61.862 1.00 26.86 ? 735 TYR B CE1 1 ATOM 11541 C CE2 . TYR B 1 699 ? 63.363 54.350 61.356 1.00 25.78 ? 735 TYR B CE2 1 ATOM 11542 C CZ . TYR B 1 699 ? 62.960 53.058 61.648 1.00 25.92 ? 735 TYR B CZ 1 ATOM 11543 O OH . TYR B 1 699 ? 63.889 52.044 61.747 1.00 24.37 ? 735 TYR B OH 1 ATOM 11544 N N . THR B 1 700 ? 56.979 55.990 59.307 1.00 25.83 ? 736 THR B N 1 ATOM 11545 C CA . THR B 1 700 ? 55.613 56.475 59.132 1.00 22.55 ? 736 THR B CA 1 ATOM 11546 C C . THR B 1 700 ? 54.991 56.980 60.432 1.00 26.60 ? 736 THR B C 1 ATOM 11547 O O . THR B 1 700 ? 54.916 56.247 61.416 1.00 24.03 ? 736 THR B O 1 ATOM 11548 C CB . THR B 1 700 ? 54.711 55.364 58.593 1.00 25.41 ? 736 THR B CB 1 ATOM 11549 O OG1 . THR B 1 700 ? 55.224 54.896 57.334 1.00 23.46 ? 736 THR B OG1 1 ATOM 11550 C CG2 . THR B 1 700 ? 53.301 55.863 58.409 1.00 23.05 ? 736 THR B CG2 1 ATOM 11551 N N . ASP B 1 701 ? 54.548 58.234 60.420 1.00 24.42 ? 737 ASP B N 1 ATOM 11552 C CA . ASP B 1 701 ? 53.835 58.845 61.548 1.00 25.42 ? 737 ASP B CA 1 ATOM 11553 C C . ASP B 1 701 ? 54.638 59.087 62.828 1.00 26.78 ? 737 ASP B C 1 ATOM 11554 O O . ASP B 1 701 ? 54.056 59.442 63.863 1.00 28.08 ? 737 ASP B O 1 ATOM 11555 C CB . ASP B 1 701 ? 52.546 58.078 61.879 1.00 26.64 ? 737 ASP B CB 1 ATOM 11556 C CG . ASP B 1 701 ? 51.466 58.240 60.806 1.00 29.06 ? 737 ASP B CG 1 ATOM 11557 O OD1 . ASP B 1 701 ? 51.631 59.065 59.867 1.00 23.56 ? 737 ASP B OD1 1 ATOM 11558 O OD2 . ASP B 1 701 ? 50.438 57.548 60.912 1.00 28.43 ? 737 ASP B OD2 1 ATOM 11559 N N . GLU B 1 702 ? 55.955 58.912 62.772 1.00 26.79 ? 738 GLU B N 1 ATOM 11560 C CA . GLU B 1 702 ? 56.793 59.203 63.941 1.00 26.86 ? 738 GLU B CA 1 ATOM 11561 C C . GLU B 1 702 ? 57.262 60.651 63.894 1.00 26.62 ? 738 GLU B C 1 ATOM 11562 O O . GLU B 1 702 ? 57.375 61.239 62.805 1.00 24.58 ? 738 GLU B O 1 ATOM 11563 C CB . GLU B 1 702 ? 57.985 58.250 64.033 1.00 25.46 ? 738 GLU B CB 1 ATOM 11564 C CG . GLU B 1 702 ? 57.613 56.803 64.303 1.00 24.60 ? 738 GLU B CG 1 ATOM 11565 C CD . GLU B 1 702 ? 57.039 56.572 65.703 1.00 35.02 ? 738 GLU B CD 1 ATOM 11566 O OE1 . GLU B 1 702 ? 57.642 57.024 66.706 1.00 32.44 ? 738 GLU B OE1 1 ATOM 11567 O OE2 . GLU B 1 702 ? 55.970 55.929 65.805 1.00 39.19 ? 738 GLU B OE2 1 ATOM 11568 N N . ASP B 1 703 ? 57.507 61.241 65.066 1.00 24.52 ? 739 ASP B N 1 ATOM 11569 C CA . ASP B 1 703 ? 57.946 62.635 65.110 1.00 27.12 ? 739 ASP B CA 1 ATOM 11570 C C . ASP B 1 703 ? 59.444 62.710 65.399 1.00 27.82 ? 739 ASP B C 1 ATOM 11571 O O . ASP B 1 703 ? 60.161 61.749 65.142 1.00 26.30 ? 739 ASP B O 1 ATOM 11572 C CB . ASP B 1 703 ? 57.106 63.477 66.091 1.00 25.91 ? 739 ASP B CB 1 ATOM 11573 C CG . ASP B 1 703 ? 57.186 62.985 67.530 1.00 32.00 ? 739 ASP B CG 1 ATOM 11574 O OD1 . ASP B 1 703 ? 58.099 62.183 67.836 1.00 30.50 ? 739 ASP B OD1 1 ATOM 11575 O OD2 . ASP B 1 703 ? 56.347 63.428 68.370 1.00 33.60 ? 739 ASP B OD2 1 ATOM 11576 N N . HIS B 1 704 ? 59.919 63.832 65.931 1.00 24.74 ? 740 HIS B N 1 ATOM 11577 C CA . HIS B 1 704 ? 61.358 64.017 66.114 1.00 24.47 ? 740 HIS B CA 1 ATOM 11578 C C . HIS B 1 704 ? 62.007 62.975 67.008 1.00 27.56 ? 740 HIS B C 1 ATOM 11579 O O . HIS B 1 704 ? 63.207 62.719 66.893 1.00 27.69 ? 740 HIS B O 1 ATOM 11580 C CB . HIS B 1 704 ? 61.685 65.402 66.686 1.00 23.25 ? 740 HIS B CB 1 ATOM 11581 C CG . HIS B 1 704 ? 63.094 65.823 66.417 1.00 27.06 ? 740 HIS B CG 1 ATOM 11582 N ND1 . HIS B 1 704 ? 63.614 65.875 65.144 1.00 24.05 ? 740 HIS B ND1 1 ATOM 11583 C CD2 . HIS B 1 704 ? 64.101 66.177 67.249 1.00 26.57 ? 740 HIS B CD2 1 ATOM 11584 C CE1 . HIS B 1 704 ? 64.881 66.242 65.200 1.00 27.82 ? 740 HIS B CE1 1 ATOM 11585 N NE2 . HIS B 1 704 ? 65.200 66.439 66.466 1.00 27.43 ? 740 HIS B NE2 1 ATOM 11586 N N . GLY B 1 705 ? 61.232 62.404 67.924 1.00 26.18 ? 741 GLY B N 1 ATOM 11587 C CA . GLY B 1 705 ? 61.787 61.489 68.906 1.00 27.23 ? 741 GLY B CA 1 ATOM 11588 C C . GLY B 1 705 ? 61.833 60.046 68.444 1.00 26.54 ? 741 GLY B C 1 ATOM 11589 O O . GLY B 1 705 ? 62.530 59.236 69.044 1.00 31.22 ? 741 GLY B O 1 ATOM 11590 N N . ILE B 1 706 ? 61.093 59.725 67.390 1.00 24.63 ? 742 ILE B N 1 ATOM 11591 C CA . ILE B 1 706 ? 60.975 58.337 66.915 1.00 28.98 ? 742 ILE B CA 1 ATOM 11592 C C . ILE B 1 706 ? 60.949 57.440 68.159 1.00 29.82 ? 742 ILE B C 1 ATOM 11593 O O . ILE B 1 706 ? 61.789 56.556 68.352 1.00 28.48 ? 742 ILE B O 1 ATOM 11594 C CB . ILE B 1 706 ? 62.107 57.953 65.917 1.00 27.95 ? 742 ILE B CB 1 ATOM 11595 C CG1 . ILE B 1 706 ? 62.243 59.027 64.833 1.00 25.20 ? 742 ILE B CG1 1 ATOM 11596 C CG2 . ILE B 1 706 ? 61.850 56.574 65.287 1.00 27.28 ? 742 ILE B CG2 1 ATOM 11597 C CD1 . ILE B 1 706 ? 63.475 58.904 63.964 1.00 24.72 ? 742 ILE B CD1 1 ATOM 11598 N N . ALA B 1 707 ? 59.963 57.702 69.008 1.00 27.39 ? 743 ALA B N 1 ATOM 11599 C CA . ALA B 1 707 ? 59.994 57.226 70.385 1.00 31.31 ? 743 ALA B CA 1 ATOM 11600 C C . ALA B 1 707 ? 58.893 56.244 70.745 1.00 30.11 ? 743 ALA B C 1 ATOM 11601 O O . ALA B 1 707 ? 58.865 55.747 71.874 1.00 27.52 ? 743 ALA B O 1 ATOM 11602 C CB . ALA B 1 707 ? 59.982 58.413 71.358 1.00 33.12 ? 743 ALA B CB 1 ATOM 11603 N N . SER B 1 708 ? 57.996 55.943 69.807 1.00 26.45 ? 744 SER B N 1 ATOM 11604 C CA . SER B 1 708 ? 57.005 54.924 70.100 1.00 27.56 ? 744 SER B CA 1 ATOM 11605 C C . SER B 1 708 ? 57.766 53.617 70.325 1.00 30.89 ? 744 SER B C 1 ATOM 11606 O O . SER B 1 708 ? 58.872 53.427 69.810 1.00 28.85 ? 744 SER B O 1 ATOM 11607 C CB . SER B 1 708 ? 55.956 54.799 68.993 1.00 28.83 ? 744 SER B CB 1 ATOM 11608 O OG . SER B 1 708 ? 56.494 54.166 67.839 1.00 35.73 ? 744 SER B OG 1 ATOM 11609 N N . SER B 1 709 ? 57.193 52.727 71.117 1.00 28.40 ? 745 SER B N 1 ATOM 11610 C CA . SER B 1 709 ? 57.906 51.531 71.531 1.00 28.93 ? 745 SER B CA 1 ATOM 11611 C C . SER B 1 709 ? 58.435 50.720 70.344 1.00 27.83 ? 745 SER B C 1 ATOM 11612 O O . SER B 1 709 ? 59.597 50.295 70.321 1.00 28.08 ? 745 SER B O 1 ATOM 11613 C CB . SER B 1 709 ? 56.988 50.661 72.381 1.00 30.95 ? 745 SER B CB 1 ATOM 11614 O OG . SER B 1 709 ? 57.664 49.474 72.720 1.00 41.42 ? 745 SER B OG 1 ATOM 11615 N N . THR B 1 710 ? 57.579 50.500 69.358 1.00 28.28 ? 746 THR B N 1 ATOM 11616 C CA . THR B 1 710 ? 57.965 49.714 68.182 1.00 29.53 ? 746 THR B CA 1 ATOM 11617 C C . THR B 1 710 ? 58.974 50.439 67.279 1.00 24.11 ? 746 THR B C 1 ATOM 11618 O O . THR B 1 710 ? 59.930 49.837 66.804 1.00 25.76 ? 746 THR B O 1 ATOM 11619 C CB . THR B 1 710 ? 56.729 49.317 67.382 1.00 27.06 ? 746 THR B CB 1 ATOM 11620 O OG1 . THR B 1 710 ? 55.976 50.496 67.095 1.00 30.82 ? 746 THR B OG1 1 ATOM 11621 C CG2 . THR B 1 710 ? 55.857 48.373 68.221 1.00 32.24 ? 746 THR B CG2 1 ATOM 11622 N N . ALA B 1 711 ? 58.775 51.730 67.043 1.00 24.82 ? 747 ALA B N 1 ATOM 11623 C CA . ALA B 1 711 ? 59.712 52.466 66.206 1.00 20.80 ? 747 ALA B CA 1 ATOM 11624 C C . ALA B 1 711 ? 61.088 52.565 66.869 1.00 26.45 ? 747 ALA B C 1 ATOM 11625 O O . ALA B 1 711 ? 62.117 52.423 66.204 1.00 22.96 ? 747 ALA B O 1 ATOM 11626 C CB . ALA B 1 711 ? 59.173 53.839 65.852 1.00 23.56 ? 747 ALA B CB 1 ATOM 11627 N N . HIS B 1 712 ? 61.104 52.809 68.178 1.00 25.43 ? 748 HIS B N 1 ATOM 11628 C CA . HIS B 1 712 ? 62.355 52.882 68.953 1.00 26.08 ? 748 HIS B CA 1 ATOM 11629 C C . HIS B 1 712 ? 63.152 51.592 68.775 1.00 25.44 ? 748 HIS B C 1 ATOM 11630 O O . HIS B 1 712 ? 64.322 51.593 68.382 1.00 23.36 ? 748 HIS B O 1 ATOM 11631 C CB . HIS B 1 712 ? 62.023 53.118 70.430 1.00 27.28 ? 748 HIS B CB 1 ATOM 11632 C CG . HIS B 1 712 ? 63.210 53.072 71.341 1.00 30.19 ? 748 HIS B CG 1 ATOM 11633 N ND1 . HIS B 1 712 ? 64.251 53.968 71.250 1.00 26.72 ? 748 HIS B ND1 1 ATOM 11634 C CD2 . HIS B 1 712 ? 63.514 52.246 72.372 1.00 30.58 ? 748 HIS B CD2 1 ATOM 11635 C CE1 . HIS B 1 712 ? 65.152 53.690 72.175 1.00 30.53 ? 748 HIS B CE1 1 ATOM 11636 N NE2 . HIS B 1 712 ? 64.735 52.642 72.865 1.00 29.70 ? 748 HIS B NE2 1 ATOM 11637 N N . GLN B 1 713 ? 62.500 50.471 69.019 1.00 26.16 ? 749 GLN B N 1 ATOM 11638 C CA . GLN B 1 713 ? 63.161 49.196 68.806 1.00 28.54 ? 749 GLN B CA 1 ATOM 11639 C C . GLN B 1 713 ? 63.632 49.043 67.374 1.00 26.51 ? 749 GLN B C 1 ATOM 11640 O O . GLN B 1 713 ? 64.738 48.567 67.127 1.00 28.83 ? 749 GLN B O 1 ATOM 11641 C CB . GLN B 1 713 ? 62.225 48.060 69.175 1.00 26.82 ? 749 GLN B CB 1 ATOM 11642 C CG . GLN B 1 713 ? 61.899 48.061 70.656 1.00 28.76 ? 749 GLN B CG 1 ATOM 11643 C CD . GLN B 1 713 ? 60.922 46.971 71.025 1.00 39.16 ? 749 GLN B CD 1 ATOM 11644 O OE1 . GLN B 1 713 ? 61.267 45.789 71.027 1.00 50.26 ? 749 GLN B OE1 1 ATOM 11645 N NE2 . GLN B 1 713 ? 59.694 47.358 71.338 1.00 43.23 ? 749 GLN B NE2 1 ATOM 11646 N N . HIS B 1 714 ? 62.801 49.454 66.422 1.00 24.55 ? 750 HIS B N 1 ATOM 11647 C CA . HIS B 1 714 ? 63.127 49.231 65.008 1.00 26.50 ? 750 HIS B CA 1 ATOM 11648 C C . HIS B 1 714 ? 64.307 50.060 64.536 1.00 27.17 ? 750 HIS B C 1 ATOM 11649 O O . HIS B 1 714 ? 65.189 49.549 63.832 1.00 23.64 ? 750 HIS B O 1 ATOM 11650 C CB . HIS B 1 714 ? 61.914 49.491 64.112 1.00 22.79 ? 750 HIS B CB 1 ATOM 11651 C CG . HIS B 1 714 ? 62.035 48.898 62.744 1.00 27.94 ? 750 HIS B CG 1 ATOM 11652 N ND1 . HIS B 1 714 ? 62.686 49.538 61.712 1.00 27.28 ? 750 HIS B ND1 1 ATOM 11653 C CD2 . HIS B 1 714 ? 61.555 47.741 62.226 1.00 27.28 ? 750 HIS B CD2 1 ATOM 11654 C CE1 . HIS B 1 714 ? 62.613 48.798 60.620 1.00 27.72 ? 750 HIS B CE1 1 ATOM 11655 N NE2 . HIS B 1 714 ? 61.927 47.706 60.902 1.00 30.51 ? 750 HIS B NE2 1 ATOM 11656 N N . ILE B 1 715 ? 64.346 51.331 64.926 1.00 26.10 ? 751 ILE B N 1 ATOM 11657 C CA . ILE B 1 715 ? 65.439 52.188 64.472 1.00 23.02 ? 751 ILE B CA 1 ATOM 11658 C C . ILE B 1 715 ? 66.787 51.747 65.058 1.00 25.54 ? 751 ILE B C 1 ATOM 11659 O O . ILE B 1 715 ? 67.785 51.658 64.344 1.00 29.21 ? 751 ILE B O 1 ATOM 11660 C CB . ILE B 1 715 ? 65.161 53.682 64.714 1.00 25.83 ? 751 ILE B CB 1 ATOM 11661 C CG1 . ILE B 1 715 ? 66.158 54.537 63.932 1.00 26.56 ? 751 ILE B CG1 1 ATOM 11662 C CG2 . ILE B 1 715 ? 65.208 54.022 66.202 1.00 24.11 ? 751 ILE B CG2 1 ATOM 11663 C CD1 . ILE B 1 715 ? 65.888 56.029 64.021 1.00 24.73 ? 751 ILE B CD1 1 ATOM 11664 N N . TYR B 1 716 ? 66.836 51.443 66.347 1.00 27.45 ? 752 TYR B N 1 ATOM 11665 C CA . TYR B 1 716 ? 68.099 50.965 66.908 1.00 27.91 ? 752 TYR B CA 1 ATOM 11666 C C . TYR B 1 716 ? 68.535 49.596 66.349 1.00 26.20 ? 752 TYR B C 1 ATOM 11667 O O . TYR B 1 716 ? 69.722 49.342 66.185 1.00 27.94 ? 752 TYR B O 1 ATOM 11668 C CB . TYR B 1 716 ? 68.097 50.999 68.437 1.00 25.29 ? 752 TYR B CB 1 ATOM 11669 C CG . TYR B 1 716 ? 68.324 52.406 68.947 1.00 27.35 ? 752 TYR B CG 1 ATOM 11670 C CD1 . TYR B 1 716 ? 69.597 52.976 68.941 1.00 25.70 ? 752 TYR B CD1 1 ATOM 11671 C CD2 . TYR B 1 716 ? 67.267 53.184 69.377 1.00 27.35 ? 752 TYR B CD2 1 ATOM 11672 C CE1 . TYR B 1 716 ? 69.808 54.283 69.391 1.00 25.61 ? 752 TYR B CE1 1 ATOM 11673 C CE2 . TYR B 1 716 ? 67.468 54.489 69.823 1.00 27.87 ? 752 TYR B CE2 1 ATOM 11674 C CZ . TYR B 1 716 ? 68.738 55.027 69.826 1.00 29.33 ? 752 TYR B CZ 1 ATOM 11675 O OH . TYR B 1 716 ? 68.926 56.312 70.270 1.00 32.63 ? 752 TYR B OH 1 ATOM 11676 N N . THR B 1 717 ? 67.578 48.729 66.056 1.00 24.65 ? 753 THR B N 1 ATOM 11677 C CA . THR B 1 717 ? 67.886 47.453 65.429 1.00 27.29 ? 753 THR B CA 1 ATOM 11678 C C . THR B 1 717 ? 68.456 47.697 64.029 1.00 27.60 ? 753 THR B C 1 ATOM 11679 O O . THR B 1 717 ? 69.427 47.059 63.614 1.00 26.91 ? 753 THR B O 1 ATOM 11680 C CB . THR B 1 717 ? 66.628 46.554 65.388 1.00 25.79 ? 753 THR B CB 1 ATOM 11681 O OG1 . THR B 1 717 ? 66.227 46.253 66.733 1.00 28.74 ? 753 THR B OG1 1 ATOM 11682 C CG2 . THR B 1 717 ? 66.907 45.257 64.665 1.00 28.61 ? 753 THR B CG2 1 ATOM 11683 N N . HIS B 1 718 ? 67.875 48.657 63.314 1.00 28.13 ? 754 HIS B N 1 ATOM 11684 C CA . HIS B 1 718 ? 68.298 48.941 61.946 1.00 25.89 ? 754 HIS B CA 1 ATOM 11685 C C . HIS B 1 718 ? 69.687 49.558 61.944 1.00 29.20 ? 754 HIS B C 1 ATOM 11686 O O . HIS B 1 718 ? 70.540 49.178 61.146 1.00 25.71 ? 754 HIS B O 1 ATOM 11687 C CB . HIS B 1 718 ? 67.292 49.869 61.246 1.00 28.06 ? 754 HIS B CB 1 ATOM 11688 C CG . HIS B 1 718 ? 67.442 49.918 59.755 1.00 29.68 ? 754 HIS B CG 1 ATOM 11689 N ND1 . HIS B 1 718 ? 67.212 48.821 58.943 1.00 28.87 ? 754 HIS B ND1 1 ATOM 11690 C CD2 . HIS B 1 718 ? 67.792 50.934 58.928 1.00 30.49 ? 754 HIS B CD2 1 ATOM 11691 C CE1 . HIS B 1 718 ? 67.430 49.163 57.684 1.00 29.46 ? 754 HIS B CE1 1 ATOM 11692 N NE2 . HIS B 1 718 ? 67.782 50.438 57.647 1.00 27.68 ? 754 HIS B NE2 1 ATOM 11693 N N . MET B 1 719 ? 69.921 50.514 62.840 1.00 25.12 ? 755 MET B N 1 ATOM 11694 C CA . MET B 1 719 ? 71.230 51.162 62.916 1.00 26.09 ? 755 MET B CA 1 ATOM 11695 C C . MET B 1 719 ? 72.328 50.194 63.360 1.00 24.07 ? 755 MET B C 1 ATOM 11696 O O . MET B 1 719 ? 73.476 50.293 62.907 1.00 25.47 ? 755 MET B O 1 ATOM 11697 C CB . MET B 1 719 ? 71.187 52.386 63.853 1.00 27.06 ? 755 MET B CB 1 ATOM 11698 C CG . MET B 1 719 ? 70.338 53.535 63.308 1.00 25.76 ? 755 MET B CG 1 ATOM 11699 S SD . MET B 1 719 ? 70.484 55.036 64.322 1.00 33.43 ? 755 MET B SD 1 ATOM 11700 C CE . MET B 1 719 ? 70.052 54.420 65.936 1.00 24.29 ? 755 MET B CE 1 ATOM 11701 N N . SER B 1 720 ? 71.982 49.264 64.245 1.00 24.02 ? 756 SER B N 1 ATOM 11702 C CA . SER B 1 720 ? 72.951 48.274 64.721 1.00 27.06 ? 756 SER B CA 1 ATOM 11703 C C . SER B 1 720 ? 73.434 47.369 63.585 1.00 29.30 ? 756 SER B C 1 ATOM 11704 O O . SER B 1 720 ? 74.626 47.057 63.506 1.00 31.55 ? 756 SER B O 1 ATOM 11705 C CB . SER B 1 720 ? 72.371 47.427 65.863 1.00 26.51 ? 756 SER B CB 1 ATOM 11706 O OG . SER B 1 720 ? 72.034 48.234 66.975 1.00 30.21 ? 756 SER B OG 1 ATOM 11707 N N . HIS B 1 721 ? 72.513 46.950 62.714 1.00 28.74 ? 757 HIS B N 1 ATOM 11708 C CA . HIS B 1 721 ? 72.880 46.162 61.528 1.00 32.02 ? 757 HIS B CA 1 ATOM 11709 C C . HIS B 1 721 ? 73.817 46.960 60.643 1.00 30.54 ? 757 HIS B C 1 ATOM 11710 O O . HIS B 1 721 ? 74.820 46.447 60.139 1.00 32.15 ? 757 HIS B O 1 ATOM 11711 C CB . HIS B 1 721 ? 71.639 45.772 60.709 1.00 31.31 ? 757 HIS B CB 1 ATOM 11712 C CG . HIS B 1 721 ? 70.756 44.763 61.381 1.00 37.43 ? 757 HIS B CG 1 ATOM 11713 N ND1 . HIS B 1 721 ? 71.254 43.742 62.162 1.00 40.53 ? 757 HIS B ND1 1 ATOM 11714 C CD2 . HIS B 1 721 ? 69.406 44.613 61.384 1.00 33.70 ? 757 HIS B CD2 1 ATOM 11715 C CE1 . HIS B 1 721 ? 70.252 43.010 62.621 1.00 41.10 ? 757 HIS B CE1 1 ATOM 11716 N NE2 . HIS B 1 721 ? 69.121 43.515 62.158 1.00 39.21 ? 757 HIS B NE2 1 ATOM 11717 N N . PHE B 1 722 ? 73.476 48.227 60.443 1.00 28.69 ? 758 PHE B N 1 ATOM 11718 C CA . PHE B 1 722 ? 74.270 49.095 59.595 1.00 23.95 ? 758 PHE B CA 1 ATOM 11719 C C . PHE B 1 722 ? 75.701 49.257 60.125 1.00 30.87 ? 758 PHE B C 1 ATOM 11720 O O . PHE B 1 722 ? 76.671 49.106 59.371 1.00 32.28 ? 758 PHE B O 1 ATOM 11721 C CB . PHE B 1 722 ? 73.588 50.457 59.451 1.00 26.10 ? 758 PHE B CB 1 ATOM 11722 C CG . PHE B 1 722 ? 74.345 51.426 58.586 1.00 28.05 ? 758 PHE B CG 1 ATOM 11723 C CD1 . PHE B 1 722 ? 74.210 51.393 57.207 1.00 30.41 ? 758 PHE B CD1 1 ATOM 11724 C CD2 . PHE B 1 722 ? 75.184 52.368 59.152 1.00 30.03 ? 758 PHE B CD2 1 ATOM 11725 C CE1 . PHE B 1 722 ? 74.909 52.271 56.408 1.00 32.79 ? 758 PHE B CE1 1 ATOM 11726 C CE2 . PHE B 1 722 ? 75.878 53.256 58.361 1.00 28.87 ? 758 PHE B CE2 1 ATOM 11727 C CZ . PHE B 1 722 ? 75.734 53.213 56.990 1.00 30.39 ? 758 PHE B CZ 1 ATOM 11728 N N . ILE B 1 723 ? 75.844 49.576 61.409 1.00 27.77 ? 759 ILE B N 1 ATOM 11729 C CA . ILE B 1 723 ? 77.173 49.795 61.992 1.00 28.98 ? 759 ILE B CA 1 ATOM 11730 C C . ILE B 1 723 ? 77.991 48.490 61.993 1.00 33.80 ? 759 ILE B C 1 ATOM 11731 O O . ILE B 1 723 ? 79.165 48.486 61.619 1.00 33.67 ? 759 ILE B O 1 ATOM 11732 C CB . ILE B 1 723 ? 77.098 50.393 63.417 1.00 32.32 ? 759 ILE B CB 1 ATOM 11733 C CG1 . ILE B 1 723 ? 76.533 51.819 63.374 1.00 28.54 ? 759 ILE B CG1 1 ATOM 11734 C CG2 . ILE B 1 723 ? 78.475 50.449 64.043 1.00 34.81 ? 759 ILE B CG2 1 ATOM 11735 C CD1 . ILE B 1 723 ? 77.376 52.803 62.549 1.00 26.54 ? 759 ILE B CD1 1 ATOM 11736 N N . LYS B 1 724 ? 77.355 47.386 62.380 1.00 31.51 ? 760 LYS B N 1 ATOM 11737 C CA . LYS B 1 724 ? 77.986 46.072 62.317 1.00 34.23 ? 760 LYS B CA 1 ATOM 11738 C C . LYS B 1 724 ? 78.478 45.711 60.905 1.00 38.90 ? 760 LYS B C 1 ATOM 11739 O O . LYS B 1 724 ? 79.610 45.257 60.750 1.00 39.58 ? 760 LYS B O 1 ATOM 11740 C CB . LYS B 1 724 ? 77.065 44.989 62.884 1.00 34.90 ? 760 LYS B CB 1 ATOM 11741 C CG . LYS B 1 724 ? 76.777 45.178 64.366 1.00 36.94 ? 760 LYS B CG 1 ATOM 11742 C CD . LYS B 1 724 ? 76.582 43.860 65.065 1.00 41.75 ? 760 LYS B CD 1 ATOM 11743 C CE . LYS B 1 724 ? 75.443 43.078 64.463 1.00 48.56 ? 760 LYS B CE 1 ATOM 11744 N NZ . LYS B 1 724 ? 75.262 41.779 65.170 1.00 57.69 ? 760 LYS B NZ 1 ATOM 11745 N N . GLN B 1 725 ? 77.640 45.919 59.886 1.00 30.75 ? 761 GLN B N 1 ATOM 11746 C CA . GLN B 1 725 ? 78.063 45.732 58.488 1.00 36.38 ? 761 GLN B CA 1 ATOM 11747 C C . GLN B 1 725 ? 79.272 46.604 58.128 1.00 40.38 ? 761 GLN B C 1 ATOM 11748 O O . GLN B 1 725 ? 80.272 46.119 57.590 1.00 41.79 ? 761 GLN B O 1 ATOM 11749 C CB . GLN B 1 725 ? 76.902 46.022 57.515 1.00 35.71 ? 761 GLN B CB 1 ATOM 11750 C CG . GLN B 1 725 ? 77.328 46.200 56.057 1.00 44.48 ? 761 GLN B CG 1 ATOM 11751 N N . CYS B 1 726 ? 79.176 47.895 58.424 1.00 37.53 ? 762 CYS B N 1 ATOM 11752 C CA . CYS B 1 726 ? 80.265 48.834 58.166 1.00 39.90 ? 762 CYS B CA 1 ATOM 11753 C C . CYS B 1 726 ? 81.588 48.399 58.809 1.00 39.85 ? 762 CYS B C 1 ATOM 11754 O O . CYS B 1 726 ? 82.658 48.617 58.239 1.00 45.37 ? 762 CYS B O 1 ATOM 11755 C CB . CYS B 1 726 ? 79.874 50.224 58.677 1.00 46.07 ? 762 CYS B CB 1 ATOM 11756 S SG . CYS B 1 726 ? 80.963 51.602 58.216 1.00 63.17 ? 762 CYS B SG 1 ATOM 11757 N N . PHE B 1 727 ? 81.516 47.791 59.992 1.00 38.15 ? 763 PHE B N 1 ATOM 11758 C CA . PHE B 1 727 ? 82.721 47.383 60.730 1.00 40.84 ? 763 PHE B CA 1 ATOM 11759 C C . PHE B 1 727 ? 83.129 45.912 60.546 1.00 43.12 ? 763 PHE B C 1 ATOM 11760 O O . PHE B 1 727 ? 84.013 45.427 61.249 1.00 39.42 ? 763 PHE B O 1 ATOM 11761 C CB . PHE B 1 727 ? 82.575 47.662 62.236 1.00 36.94 ? 763 PHE B CB 1 ATOM 11762 C CG . PHE B 1 727 ? 82.613 49.119 62.598 1.00 35.73 ? 763 PHE B CG 1 ATOM 11763 C CD1 . PHE B 1 727 ? 82.958 50.076 61.663 1.00 38.06 ? 763 PHE B CD1 1 ATOM 11764 C CD2 . PHE B 1 727 ? 82.314 49.528 63.880 1.00 34.32 ? 763 PHE B CD2 1 ATOM 11765 C CE1 . PHE B 1 727 ? 82.993 51.412 62.003 1.00 39.02 ? 763 PHE B CE1 1 ATOM 11766 C CE2 . PHE B 1 727 ? 82.347 50.866 64.221 1.00 33.39 ? 763 PHE B CE2 1 ATOM 11767 C CZ . PHE B 1 727 ? 82.680 51.805 63.285 1.00 28.88 ? 763 PHE B CZ 1 ATOM 11768 N N . SER B 1 728 ? 82.480 45.203 59.628 1.00 45.47 ? 764 SER B N 1 ATOM 11769 C CA . SER B 1 728 ? 82.820 43.802 59.367 1.00 49.08 ? 764 SER B CA 1 ATOM 11770 C C . SER B 1 728 ? 82.764 42.964 60.632 1.00 56.99 ? 764 SER B C 1 ATOM 11771 O O . SER B 1 728 ? 83.433 41.935 60.717 1.00 64.06 ? 764 SER B O 1 ATOM 11772 C CB . SER B 1 728 ? 84.222 43.689 58.771 1.00 44.46 ? 764 SER B CB 1 ATOM 11773 O OG . SER B 1 728 ? 84.374 44.593 57.695 1.00 47.87 ? 764 SER B OG 1 ATOM 11774 N N . LEU B 1 729 ? 81.992 43.417 61.620 1.00 56.91 ? 765 LEU B N 1 ATOM 11775 C CA . LEU B 1 729 ? 81.790 42.653 62.846 1.00 60.62 ? 765 LEU B CA 1 ATOM 11776 C C . LEU B 1 729 ? 80.798 41.519 62.587 1.00 68.84 ? 765 LEU B C 1 ATOM 11777 O O . LEU B 1 729 ? 79.707 41.754 62.051 1.00 61.38 ? 765 LEU B O 1 ATOM 11778 C CB . LEU B 1 729 ? 81.266 43.546 63.971 1.00 55.23 ? 765 LEU B CB 1 ATOM 11779 C CG . LEU B 1 729 ? 82.103 44.718 64.494 1.00 54.41 ? 765 LEU B CG 1 ATOM 11780 C CD1 . LEU B 1 729 ? 81.363 45.397 65.646 1.00 43.02 ? 765 LEU B CD1 1 ATOM 11781 C CD2 . LEU B 1 729 ? 83.506 44.286 64.936 1.00 56.53 ? 765 LEU B CD2 1 ATOM 11782 N N . PRO B 1 730 ? 81.178 40.283 62.963 1.00 75.19 ? 766 PRO B N 1 ATOM 11783 C CA . PRO B 1 730 ? 80.337 39.094 62.758 1.00 76.25 ? 766 PRO B CA 1 ATOM 11784 C C . PRO B 1 730 ? 78.944 39.256 63.374 1.00 76.13 ? 766 PRO B C 1 ATOM 11785 O O . PRO B 1 730 ? 78.042 39.798 62.729 1.00 72.07 ? 766 PRO B O 1 ATOM 11786 C CB . PRO B 1 730 ? 81.112 37.988 63.487 1.00 76.68 ? 766 PRO B CB 1 ATOM 11787 C CG . PRO B 1 730 ? 82.541 38.451 63.468 1.00 75.93 ? 766 PRO B CG 1 ATOM 11788 C CD . PRO B 1 730 ? 82.468 39.950 63.599 1.00 73.08 ? 766 PRO B CD 1 HETATM 11789 C C1 . NAG C 2 . ? 56.345 61.940 -6.265 1.00 32.95 ? 851 NAG A C1 1 HETATM 11790 C C2 . NAG C 2 . ? 55.931 63.326 -5.751 1.00 32.92 ? 851 NAG A C2 1 HETATM 11791 C C3 . NAG C 2 . ? 54.800 63.914 -6.592 1.00 35.87 ? 851 NAG A C3 1 HETATM 11792 C C4 . NAG C 2 . ? 55.203 63.896 -8.062 1.00 36.58 ? 851 NAG A C4 1 HETATM 11793 C C5 . NAG C 2 . ? 55.612 62.482 -8.452 1.00 30.81 ? 851 NAG A C5 1 HETATM 11794 C C6 . NAG C 2 . ? 56.047 62.434 -9.915 1.00 36.70 ? 851 NAG A C6 1 HETATM 11795 C C7 . NAG C 2 . ? 56.243 63.681 -3.345 1.00 35.02 ? 851 NAG A C7 1 HETATM 11796 C C8 . NAG C 2 . ? 55.549 63.654 -2.016 1.00 34.22 ? 851 NAG A C8 1 HETATM 11797 N N2 . NAG C 2 . ? 55.515 63.236 -4.366 1.00 36.41 ? 851 NAG A N2 1 HETATM 11798 O O3 . NAG C 2 . ? 54.509 65.233 -6.174 1.00 33.35 ? 851 NAG A O3 1 HETATM 11799 O O4 . NAG C 2 . ? 54.135 64.330 -8.887 1.00 38.50 ? 851 NAG A O4 1 HETATM 11800 O O5 . NAG C 2 . ? 56.675 62.052 -7.627 1.00 33.62 ? 851 NAG A O5 1 HETATM 11801 O O6 . NAG C 2 . ? 57.005 63.446 -10.127 1.00 34.71 ? 851 NAG A O6 1 HETATM 11802 O O7 . NAG C 2 . ? 57.404 64.079 -3.447 1.00 35.91 ? 851 NAG A O7 1 HETATM 11803 C C1 . NAG D 2 . ? 52.364 83.879 26.990 1.00 55.93 ? 1501 NAG A C1 1 HETATM 11804 C C2 . NAG D 2 . ? 51.847 85.085 26.189 1.00 56.87 ? 1501 NAG A C2 1 HETATM 11805 C C3 . NAG D 2 . ? 52.944 86.103 25.883 1.00 59.92 ? 1501 NAG A C3 1 HETATM 11806 C C4 . NAG D 2 . ? 53.699 86.440 27.160 1.00 62.32 ? 1501 NAG A C4 1 HETATM 11807 C C5 . NAG D 2 . ? 54.257 85.143 27.739 1.00 62.72 ? 1501 NAG A C5 1 HETATM 11808 C C6 . NAG D 2 . ? 55.160 85.404 28.948 1.00 61.29 ? 1501 NAG A C6 1 HETATM 11809 C C7 . NAG D 2 . ? 49.915 84.792 24.733 1.00 58.12 ? 1501 NAG A C7 1 HETATM 11810 C C8 . NAG D 2 . ? 49.377 84.215 23.454 1.00 55.48 ? 1501 NAG A C8 1 HETATM 11811 N N2 . NAG D 2 . ? 51.228 84.670 24.939 1.00 60.63 ? 1501 NAG A N2 1 HETATM 11812 O O3 . NAG D 2 . ? 52.390 87.268 25.300 1.00 58.72 ? 1501 NAG A O3 1 HETATM 11813 O O4 . NAG D 2 . ? 54.744 87.355 26.901 1.00 63.32 ? 1501 NAG A O4 1 HETATM 11814 O O5 . NAG D 2 . ? 53.191 84.270 28.074 1.00 58.37 ? 1501 NAG A O5 1 HETATM 11815 O O6 . NAG D 2 . ? 54.471 86.166 29.914 1.00 61.90 ? 1501 NAG A O6 1 HETATM 11816 O O7 . NAG D 2 . ? 49.161 85.341 25.539 1.00 55.33 ? 1501 NAG A O7 1 HETATM 11817 C C1 . NAG E 2 . ? 28.504 67.906 7.492 1.00 60.85 ? 2191 NAG A C1 1 HETATM 11818 C C2 . NAG E 2 . ? 28.065 69.029 6.521 1.00 64.06 ? 2191 NAG A C2 1 HETATM 11819 C C3 . NAG E 2 . ? 26.836 69.808 6.993 1.00 64.47 ? 2191 NAG A C3 1 HETATM 11820 C C4 . NAG E 2 . ? 25.758 68.893 7.563 1.00 62.73 ? 2191 NAG A C4 1 HETATM 11821 C C5 . NAG E 2 . ? 26.318 67.867 8.547 1.00 54.64 ? 2191 NAG A C5 1 HETATM 11822 C C6 . NAG E 2 . ? 25.235 66.848 8.873 1.00 52.42 ? 2191 NAG A C6 1 HETATM 11823 C C7 . NAG E 2 . ? 29.774 70.126 5.113 1.00 68.67 ? 2191 NAG A C7 1 HETATM 11824 C C8 . NAG E 2 . ? 31.000 70.999 5.145 1.00 63.70 ? 2191 NAG A C8 1 HETATM 11825 N N2 . NAG E 2 . ? 29.140 69.987 6.282 1.00 61.67 ? 2191 NAG A N2 1 HETATM 11826 O O3 . NAG E 2 . ? 26.296 70.515 5.893 1.00 66.89 ? 2191 NAG A O3 1 HETATM 11827 O O4 . NAG E 2 . ? 24.767 69.676 8.200 1.00 61.72 ? 2191 NAG A O4 1 HETATM 11828 O O5 . NAG E 2 . ? 27.416 67.155 8.016 1.00 49.91 ? 2191 NAG A O5 1 HETATM 11829 O O6 . NAG E 2 . ? 24.086 67.529 9.328 1.00 57.69 ? 2191 NAG A O6 1 HETATM 11830 O O7 . NAG E 2 . ? 29.408 69.586 4.059 1.00 67.32 ? 2191 NAG A O7 1 HETATM 11831 C C1 . NAG F 2 . ? 28.225 69.988 40.026 1.00 39.78 ? 2291 NAG A C1 1 HETATM 11832 C C2 . NAG F 2 . ? 27.151 70.986 39.577 1.00 41.57 ? 2291 NAG A C2 1 HETATM 11833 C C3 . NAG F 2 . ? 26.555 71.775 40.737 1.00 45.68 ? 2291 NAG A C3 1 HETATM 11834 C C4 . NAG F 2 . ? 26.203 70.874 41.910 1.00 47.80 ? 2291 NAG A C4 1 HETATM 11835 C C5 . NAG F 2 . ? 27.423 70.029 42.239 1.00 47.35 ? 2291 NAG A C5 1 HETATM 11836 C C6 . NAG F 2 . ? 27.224 69.176 43.490 1.00 48.18 ? 2291 NAG A C6 1 HETATM 11837 C C7 . NAG F 2 . ? 27.407 71.801 37.327 1.00 40.17 ? 2291 NAG A C7 1 HETATM 11838 C C8 . NAG F 2 . ? 27.913 72.877 36.415 1.00 37.09 ? 2291 NAG A C8 1 HETATM 11839 N N2 . NAG F 2 . ? 27.692 71.930 38.613 1.00 39.09 ? 2291 NAG A N2 1 HETATM 11840 O O3 . NAG F 2 . ? 25.422 72.484 40.288 1.00 49.65 ? 2291 NAG A O3 1 HETATM 11841 O O4 . NAG F 2 . ? 25.879 71.676 43.026 1.00 57.86 ? 2291 NAG A O4 1 HETATM 11842 O O5 . NAG F 2 . ? 27.756 69.228 41.123 1.00 39.41 ? 2291 NAG A O5 1 HETATM 11843 O O6 . NAG F 2 . ? 26.086 68.368 43.321 1.00 53.72 ? 2291 NAG A O6 1 HETATM 11844 O O7 . NAG F 2 . ? 26.765 70.845 36.893 1.00 45.68 ? 2291 NAG A O7 1 HETATM 11845 C C1 . NAG G 2 . ? 24.522 71.437 43.467 1.00 60.76 ? 2292 NAG A C1 1 HETATM 11846 C C2 . NAG G 2 . ? 24.469 71.719 44.973 1.00 63.51 ? 2292 NAG A C2 1 HETATM 11847 C C3 . NAG G 2 . ? 23.046 71.750 45.518 1.00 66.44 ? 2292 NAG A C3 1 HETATM 11848 C C4 . NAG G 2 . ? 22.184 72.666 44.660 1.00 65.83 ? 2292 NAG A C4 1 HETATM 11849 C C5 . NAG G 2 . ? 22.240 72.184 43.211 1.00 63.67 ? 2292 NAG A C5 1 HETATM 11850 C C6 . NAG G 2 . ? 21.428 73.094 42.302 1.00 60.32 ? 2292 NAG A C6 1 HETATM 11851 C C7 . NAG G 2 . ? 26.433 71.104 46.256 1.00 60.26 ? 2292 NAG A C7 1 HETATM 11852 C C8 . NAG G 2 . ? 27.089 70.053 47.103 1.00 54.92 ? 2292 NAG A C8 1 HETATM 11853 N N2 . NAG G 2 . ? 25.268 70.754 45.710 1.00 58.90 ? 2292 NAG A N2 1 HETATM 11854 O O3 . NAG G 2 . ? 23.080 72.211 46.850 1.00 63.27 ? 2292 NAG A O3 1 HETATM 11855 O O4 . NAG G 2 . ? 20.853 72.692 45.146 1.00 66.29 ? 2292 NAG A O4 1 HETATM 11856 O O5 . NAG G 2 . ? 23.571 72.193 42.730 1.00 61.64 ? 2292 NAG A O5 1 HETATM 11857 O O6 . NAG G 2 . ? 22.146 74.299 42.149 1.00 62.29 ? 2292 NAG A O6 1 HETATM 11858 O O7 . NAG G 2 . ? 26.961 72.213 46.086 1.00 57.22 ? 2292 NAG A O7 1 HETATM 11859 C C1 . NAG H 2 . ? 27.103 84.024 28.111 1.00 61.37 ? 2811 NAG A C1 1 HETATM 11860 C C2 . NAG H 2 . ? 26.471 85.410 28.108 1.00 67.51 ? 2811 NAG A C2 1 HETATM 11861 C C3 . NAG H 2 . ? 27.208 86.269 29.129 1.00 67.64 ? 2811 NAG A C3 1 HETATM 11862 C C4 . NAG H 2 . ? 27.168 85.574 30.492 1.00 66.25 ? 2811 NAG A C4 1 HETATM 11863 C C5 . NAG H 2 . ? 27.553 84.093 30.407 1.00 63.88 ? 2811 NAG A C5 1 HETATM 11864 C C6 . NAG H 2 . ? 27.269 83.358 31.715 1.00 67.39 ? 2811 NAG A C6 1 HETATM 11865 C C7 . NAG H 2 . ? 25.316 86.328 26.177 1.00 69.58 ? 2811 NAG A C7 1 HETATM 11866 C C8 . NAG H 2 . ? 25.396 87.237 24.983 1.00 67.22 ? 2811 NAG A C8 1 HETATM 11867 N N2 . NAG H 2 . ? 26.466 86.001 26.778 1.00 63.25 ? 2811 NAG A N2 1 HETATM 11868 O O3 . NAG H 2 . ? 26.627 87.555 29.205 1.00 64.99 ? 2811 NAG A O3 1 HETATM 11869 O O4 . NAG H 2 . ? 28.057 86.224 31.375 1.00 67.69 ? 2811 NAG A O4 1 HETATM 11870 O O5 . NAG H 2 . ? 26.861 83.432 29.366 1.00 62.74 ? 2811 NAG A O5 1 HETATM 11871 O O6 . NAG H 2 . ? 25.945 82.872 31.691 1.00 73.56 ? 2811 NAG A O6 1 HETATM 11872 O O7 . NAG H 2 . ? 24.216 85.917 26.557 1.00 66.36 ? 2811 NAG A O7 1 HETATM 11873 C C1 . NAG I 2 . ? 45.246 23.344 40.788 1.00 64.19 ? 5201 NAG A C1 1 HETATM 11874 C C2 . NAG I 2 . ? 45.455 24.822 41.119 1.00 58.38 ? 5201 NAG A C2 1 HETATM 11875 C C3 . NAG I 2 . ? 46.007 24.946 42.530 1.00 65.75 ? 5201 NAG A C3 1 HETATM 11876 C C4 . NAG I 2 . ? 45.126 24.228 43.552 1.00 68.22 ? 5201 NAG A C4 1 HETATM 11877 C C5 . NAG I 2 . ? 44.542 22.888 43.090 1.00 66.78 ? 5201 NAG A C5 1 HETATM 11878 C C6 . NAG I 2 . ? 43.204 22.692 43.804 1.00 69.15 ? 5201 NAG A C6 1 HETATM 11879 C C7 . NAG I 2 . ? 45.902 26.117 39.108 1.00 53.79 ? 5201 NAG A C7 1 HETATM 11880 C C8 . NAG I 2 . ? 46.843 27.069 38.420 1.00 47.62 ? 5201 NAG A C8 1 HETATM 11881 N N2 . NAG I 2 . ? 46.361 25.466 40.179 1.00 52.85 ? 5201 NAG A N2 1 HETATM 11882 O O3 . NAG I 2 . ? 46.112 26.315 42.878 1.00 64.65 ? 5201 NAG A O3 1 HETATM 11883 O O4 . NAG I 2 . ? 45.889 24.005 44.725 1.00 64.96 ? 5201 NAG A O4 1 HETATM 11884 O O5 . NAG I 2 . ? 44.311 22.770 41.691 1.00 69.28 ? 5201 NAG A O5 1 HETATM 11885 O O6 . NAG I 2 . ? 42.759 21.359 43.686 1.00 69.60 ? 5201 NAG A O6 1 HETATM 11886 O O7 . NAG I 2 . ? 44.759 25.959 38.673 1.00 53.12 ? 5201 NAG A O7 1 HETATM 11887 C C01 . KXB J 3 . ? 47.492 49.178 37.185 1.00 27.15 ? 1 KXB A C01 1 HETATM 11888 C C02 . KXB J 3 . ? 47.357 48.702 38.473 1.00 25.66 ? 1 KXB A C02 1 HETATM 11889 C C03 . KXB J 3 . ? 48.470 50.691 39.350 1.00 28.14 ? 1 KXB A C03 1 HETATM 11890 C C04 . KXB J 3 . ? 48.108 50.396 36.965 1.00 29.40 ? 1 KXB A C04 1 HETATM 11891 C C05 . KXB J 3 . ? 48.277 50.919 35.592 1.00 30.68 ? 1 KXB A C05 1 HETATM 11892 C C06 . KXB J 3 . ? 49.499 50.783 34.966 1.00 33.57 ? 1 KXB A C06 1 HETATM 11893 C C07 . KXB J 3 . ? 47.253 51.574 34.882 1.00 27.57 ? 1 KXB A C07 1 HETATM 11894 C C08 . KXB J 3 . ? 47.841 49.475 39.529 1.00 30.43 ? 1 KXB A C08 1 HETATM 11895 C C09 . KXB J 3 . ? 48.591 51.126 38.050 1.00 31.21 ? 1 KXB A C09 1 HETATM 11896 C C10 . KXB J 3 . ? 49.670 51.304 33.675 1.00 32.34 ? 1 KXB A C10 1 HETATM 11897 C C11 . KXB J 3 . ? 47.514 52.069 33.588 1.00 30.39 ? 1 KXB A C11 1 HETATM 11898 C C12 . KXB J 3 . ? 51.055 51.020 33.214 1.00 37.91 ? 1 KXB A C12 1 HETATM 11899 C C13 . KXB J 3 . ? 50.774 50.151 35.443 1.00 36.12 ? 1 KXB A C13 1 HETATM 11900 C C14 . KXB J 3 . ? 46.484 52.771 32.757 1.00 32.31 ? 1 KXB A C14 1 HETATM 11901 C C15 . KXB J 3 . ? 55.299 51.939 35.861 1.00 37.52 ? 1 KXB A C15 1 HETATM 11902 C C16 . KXB J 3 . ? 45.889 51.742 35.503 1.00 27.96 ? 1 KXB A C16 1 HETATM 11903 C C17 . KXB J 3 . ? 53.029 49.800 34.179 1.00 36.98 ? 1 KXB A C17 1 HETATM 11904 C C18 . KXB J 3 . ? 53.862 50.031 35.520 1.00 40.19 ? 1 KXB A C18 1 HETATM 11905 N N19 . KXB J 3 . ? 48.720 51.936 32.947 1.00 31.67 ? 1 KXB A N19 1 HETATM 11906 N N20 . KXB J 3 . ? 51.656 50.321 34.253 1.00 36.58 ? 1 KXB A N20 1 HETATM 11907 N N21 . KXB J 3 . ? 45.958 52.717 36.558 1.00 27.13 ? 1 KXB A N21 1 HETATM 11908 O O22 . KXB J 3 . ? 51.585 51.281 32.141 1.00 42.84 ? 1 KXB A O22 1 HETATM 11909 O O23 . KXB J 3 . ? 53.940 51.440 35.752 1.00 44.32 ? 1 KXB A O23 1 HETATM 11910 CL CL1 . KXB J 3 . ? 47.677 48.886 41.116 1.00 34.41 ? 1 KXB A CL1 1 HETATM 11911 CL CL2 . KXB J 3 . ? 49.349 52.619 37.768 1.00 37.90 ? 1 KXB A CL2 1 HETATM 11912 C C1 . NAG K 2 . ? 55.989 62.198 112.010 1.00 35.06 ? 851 NAG B C1 1 HETATM 11913 C C2 . NAG K 2 . ? 54.618 62.650 111.498 1.00 35.03 ? 851 NAG B C2 1 HETATM 11914 C C3 . NAG K 2 . ? 54.015 63.757 112.364 1.00 36.64 ? 851 NAG B C3 1 HETATM 11915 C C4 . NAG K 2 . ? 54.013 63.290 113.818 1.00 37.13 ? 851 NAG B C4 1 HETATM 11916 C C5 . NAG K 2 . ? 55.425 62.910 114.224 1.00 33.20 ? 851 NAG B C5 1 HETATM 11917 C C6 . NAG K 2 . ? 55.470 62.409 115.669 1.00 33.62 ? 851 NAG B C6 1 HETATM 11918 C C7 . NAG K 2 . ? 54.229 62.350 109.151 1.00 40.02 ? 851 NAG B C7 1 HETATM 11919 C C8 . NAG K 2 . ? 54.335 62.920 107.761 1.00 31.84 ? 851 NAG B C8 1 HETATM 11920 N N2 . NAG K 2 . ? 54.758 63.074 110.129 1.00 32.65 ? 851 NAG B N2 1 HETATM 11921 O O3 . NAG K 2 . ? 52.687 64.026 111.968 1.00 35.93 ? 851 NAG B O3 1 HETATM 11922 O O4 . NAG K 2 . ? 53.516 64.292 114.677 1.00 41.69 ? 851 NAG B O4 1 HETATM 11923 O O5 . NAG K 2 . ? 55.873 61.873 113.372 1.00 33.67 ? 851 NAG B O5 1 HETATM 11924 O O6 . NAG K 2 . ? 54.376 61.548 115.878 1.00 32.10 ? 851 NAG B O6 1 HETATM 11925 O O7 . NAG K 2 . ? 53.669 61.267 109.347 1.00 36.61 ? 851 NAG B O7 1 HETATM 11926 C C1 . NAG L 2 . ? 49.076 48.887 96.892 1.00 61.81 ? 921 NAG B C1 1 HETATM 11927 C C2 . NAG L 2 . ? 49.870 48.086 95.860 1.00 61.16 ? 921 NAG B C2 1 HETATM 11928 C C3 . NAG L 2 . ? 50.480 46.825 96.470 1.00 65.68 ? 921 NAG B C3 1 HETATM 11929 C C4 . NAG L 2 . ? 51.296 47.199 97.701 1.00 65.78 ? 921 NAG B C4 1 HETATM 11930 C C5 . NAG L 2 . ? 50.436 47.996 98.676 1.00 60.67 ? 921 NAG B C5 1 HETATM 11931 C C6 . NAG L 2 . ? 51.266 48.427 99.885 1.00 60.87 ? 921 NAG B C6 1 HETATM 11932 C C7 . NAG L 2 . ? 49.336 48.302 93.524 1.00 64.02 ? 921 NAG B C7 1 HETATM 11933 C C8 . NAG L 2 . ? 50.799 48.499 93.237 1.00 65.29 ? 921 NAG B C8 1 HETATM 11934 N N2 . NAG L 2 . ? 49.040 47.775 94.710 1.00 61.77 ? 921 NAG B N2 1 HETATM 11935 O O3 . NAG L 2 . ? 51.324 46.188 95.539 1.00 68.92 ? 921 NAG B O3 1 HETATM 11936 O O4 . NAG L 2 . ? 51.794 46.033 98.325 1.00 66.61 ? 921 NAG B O4 1 HETATM 11937 O O5 . NAG L 2 . ? 49.876 49.134 98.040 1.00 60.09 ? 921 NAG B O5 1 HETATM 11938 O O6 . NAG L 2 . ? 50.471 49.206 100.757 1.00 62.78 ? 921 NAG B O6 1 HETATM 11939 O O7 . NAG L 2 . ? 48.485 48.627 92.693 1.00 65.78 ? 921 NAG B O7 1 HETATM 11940 C C1 . NAG M 2 . ? 33.954 64.149 79.025 1.00 59.90 ? 1501 NAG B C1 1 HETATM 11941 C C2 . NAG M 2 . ? 32.610 64.601 79.616 1.00 61.39 ? 1501 NAG B C2 1 HETATM 11942 C C3 . NAG M 2 . ? 31.625 63.475 79.979 1.00 69.01 ? 1501 NAG B C3 1 HETATM 11943 C C4 . NAG M 2 . ? 31.741 62.219 79.115 1.00 70.37 ? 1501 NAG B C4 1 HETATM 11944 C C5 . NAG M 2 . ? 33.204 61.925 78.784 1.00 73.51 ? 1501 NAG B C5 1 HETATM 11945 C C6 . NAG M 2 . ? 33.342 60.716 77.859 1.00 77.51 ? 1501 NAG B C6 1 HETATM 11946 C C7 . NAG M 2 . ? 32.768 66.737 80.800 1.00 55.51 ? 1501 NAG B C7 1 HETATM 11947 C C8 . NAG M 2 . ? 33.188 67.439 82.061 1.00 40.89 ? 1501 NAG B C8 1 HETATM 11948 N N2 . NAG M 2 . ? 32.857 65.405 80.806 1.00 56.94 ? 1501 NAG B N2 1 HETATM 11949 O O3 . NAG M 2 . ? 30.298 63.971 79.883 1.00 66.01 ? 1501 NAG B O3 1 HETATM 11950 O O4 . NAG M 2 . ? 31.179 61.124 79.814 1.00 72.63 ? 1501 NAG B O4 1 HETATM 11951 O O5 . NAG M 2 . ? 33.786 63.051 78.157 1.00 65.49 ? 1501 NAG B O5 1 HETATM 11952 O O6 . NAG M 2 . ? 34.002 61.114 76.672 1.00 82.27 ? 1501 NAG B O6 1 HETATM 11953 O O7 . NAG M 2 . ? 32.375 67.385 79.822 1.00 57.52 ? 1501 NAG B O7 1 HETATM 11954 C C1 . NAG N 2 . ? 47.532 89.074 98.242 1.00 62.60 ? 2191 NAG B C1 1 HETATM 11955 C C2 . NAG N 2 . ? 46.410 89.392 99.257 1.00 70.50 ? 2191 NAG B C2 1 HETATM 11956 C C3 . NAG N 2 . ? 45.469 90.521 98.823 1.00 67.17 ? 2191 NAG B C3 1 HETATM 11957 C C4 . NAG N 2 . ? 46.256 91.700 98.251 1.00 69.13 ? 2191 NAG B C4 1 HETATM 11958 C C5 . NAG N 2 . ? 47.209 91.210 97.156 1.00 61.26 ? 2191 NAG B C5 1 HETATM 11959 C C6 . NAG N 2 . ? 48.004 92.375 96.578 1.00 58.01 ? 2191 NAG B C6 1 HETATM 11960 C C7 . NAG N 2 . ? 45.502 87.791 100.868 1.00 70.58 ? 2191 NAG B C7 1 HETATM 11961 C C8 . NAG N 2 . ? 45.291 86.317 101.091 1.00 67.14 ? 2191 NAG B C8 1 HETATM 11962 N N2 . NAG N 2 . ? 45.630 88.203 99.602 1.00 70.17 ? 2191 NAG B N2 1 HETATM 11963 O O3 . NAG N 2 . ? 44.722 90.940 99.948 1.00 65.35 ? 2191 NAG B O3 1 HETATM 11964 O O4 . NAG N 2 . ? 45.387 92.706 97.748 1.00 66.19 ? 2191 NAG B O4 1 HETATM 11965 O O5 . NAG N 2 . ? 48.114 90.237 97.655 1.00 59.57 ? 2191 NAG B O5 1 HETATM 11966 O O6 . NAG N 2 . ? 48.892 92.862 97.564 1.00 63.65 ? 2191 NAG B O6 1 HETATM 11967 O O7 . NAG N 2 . ? 45.556 88.566 101.826 1.00 69.12 ? 2191 NAG B O7 1 HETATM 11968 C C1 . NAG O 2 . ? 46.011 89.245 65.680 1.00 44.30 ? 2291 NAG B C1 1 HETATM 11969 C C2 . NAG O 2 . ? 44.917 90.244 66.050 1.00 44.37 ? 2291 NAG B C2 1 HETATM 11970 C C3 . NAG O 2 . ? 44.174 90.763 64.816 1.00 47.86 ? 2291 NAG B C3 1 HETATM 11971 C C4 . NAG O 2 . ? 45.141 91.213 63.720 1.00 51.59 ? 2291 NAG B C4 1 HETATM 11972 C C5 . NAG O 2 . ? 46.153 90.099 63.509 1.00 50.01 ? 2291 NAG B C5 1 HETATM 11973 C C6 . NAG O 2 . ? 47.130 90.465 62.401 1.00 47.98 ? 2291 NAG B C6 1 HETATM 11974 C C7 . NAG O 2 . ? 43.998 89.881 68.263 1.00 42.69 ? 2291 NAG B C7 1 HETATM 11975 C C8 . NAG O 2 . ? 43.018 89.125 69.118 1.00 37.75 ? 2291 NAG B C8 1 HETATM 11976 N N2 . NAG O 2 . ? 43.965 89.632 66.959 1.00 38.63 ? 2291 NAG B N2 1 HETATM 11977 O O3 . NAG O 2 . ? 43.299 91.802 65.204 1.00 52.78 ? 2291 NAG B O3 1 HETATM 11978 O O4 . NAG O 2 . ? 44.477 91.410 62.484 1.00 56.62 ? 2291 NAG B O4 1 HETATM 11979 O O5 . NAG O 2 . ? 46.850 89.841 64.712 1.00 40.82 ? 2291 NAG B O5 1 HETATM 11980 O O6 . NAG O 2 . ? 47.934 91.501 62.905 1.00 51.25 ? 2291 NAG B O6 1 HETATM 11981 O O7 . NAG O 2 . ? 44.792 90.672 68.771 1.00 43.52 ? 2291 NAG B O7 1 HETATM 11982 C C1 . NAG P 2 . ? 44.088 92.783 62.222 1.00 64.75 ? 2292 NAG B C1 1 HETATM 11983 C C2 . NAG P 2 . ? 43.682 92.878 60.748 1.00 65.17 ? 2292 NAG B C2 1 HETATM 11984 C C3 . NAG P 2 . ? 43.048 94.233 60.395 1.00 68.41 ? 2292 NAG B C3 1 HETATM 11985 C C4 . NAG P 2 . ? 43.110 95.237 61.552 1.00 70.75 ? 2292 NAG B C4 1 HETATM 11986 C C5 . NAG P 2 . ? 42.716 94.635 62.906 1.00 69.34 ? 2292 NAG B C5 1 HETATM 11987 C C6 . NAG P 2 . ? 41.228 94.841 63.178 1.00 69.56 ? 2292 NAG B C6 1 HETATM 11988 C C7 . NAG P 2 . ? 45.071 91.324 59.500 1.00 55.28 ? 2292 NAG B C7 1 HETATM 11989 C C8 . NAG P 2 . ? 46.457 91.030 59.003 1.00 53.58 ? 2292 NAG B C8 1 HETATM 11990 N N2 . NAG P 2 . ? 44.825 92.572 59.897 1.00 58.73 ? 2292 NAG B N2 1 HETATM 11991 O O3 . NAG P 2 . ? 41.703 94.070 59.985 1.00 68.09 ? 2292 NAG B O3 1 HETATM 11992 O O4 . NAG P 2 . ? 44.396 95.819 61.639 1.00 75.56 ? 2292 NAG B O4 1 HETATM 11993 O O5 . NAG P 2 . ? 43.021 93.250 63.027 1.00 66.97 ? 2292 NAG B O5 1 HETATM 11994 O O6 . NAG P 2 . ? 40.586 93.585 63.231 1.00 72.06 ? 2292 NAG B O6 1 HETATM 11995 O O7 . NAG P 2 . ? 44.220 90.435 59.532 1.00 53.60 ? 2292 NAG B O7 1 HETATM 11996 C C1 . NAG Q 2 . ? 93.807 76.279 65.182 1.00 66.10 ? 5201 NAG B C1 1 HETATM 11997 C C2 . NAG Q 2 . ? 92.358 75.861 64.920 1.00 65.11 ? 5201 NAG B C2 1 HETATM 11998 C C3 . NAG Q 2 . ? 92.227 75.293 63.502 1.00 63.36 ? 5201 NAG B C3 1 HETATM 11999 C C4 . NAG Q 2 . ? 92.871 76.219 62.467 1.00 71.11 ? 5201 NAG B C4 1 HETATM 12000 C C5 . NAG Q 2 . ? 94.302 76.579 62.857 1.00 71.01 ? 5201 NAG B C5 1 HETATM 12001 C C6 . NAG Q 2 . ? 94.876 77.645 61.930 1.00 69.74 ? 5201 NAG B C6 1 HETATM 12002 C C7 . NAG Q 2 . ? 91.181 75.181 67.017 1.00 58.82 ? 5201 NAG B C7 1 HETATM 12003 C C8 . NAG Q 2 . ? 90.341 74.057 67.559 1.00 49.84 ? 5201 NAG B C8 1 HETATM 12004 N N2 . NAG Q 2 . ? 91.922 74.894 65.930 1.00 61.60 ? 5201 NAG B N2 1 HETATM 12005 O O3 . NAG Q 2 . ? 90.868 75.118 63.167 1.00 60.72 ? 5201 NAG B O3 1 HETATM 12006 O O4 . NAG Q 2 . ? 92.859 75.621 61.184 1.00 65.80 ? 5201 NAG B O4 1 HETATM 12007 O O5 . NAG Q 2 . ? 94.320 77.113 64.162 1.00 71.45 ? 5201 NAG B O5 1 HETATM 12008 O O6 . NAG Q 2 . ? 94.353 78.903 62.307 1.00 70.59 ? 5201 NAG B O6 1 HETATM 12009 O O7 . NAG Q 2 . ? 91.160 76.280 67.587 1.00 55.76 ? 5201 NAG B O7 1 HETATM 12010 C C01 . KXB R 3 . ? 68.135 71.639 68.817 1.00 31.39 ? 2 KXB B C01 1 HETATM 12011 C C02 . KXB R 3 . ? 68.596 71.807 67.526 1.00 26.86 ? 2 KXB B C02 1 HETATM 12012 C C03 . KXB R 3 . ? 66.730 70.540 66.644 1.00 33.84 ? 2 KXB B C03 1 HETATM 12013 C C04 . KXB R 3 . ? 66.968 70.931 69.033 1.00 32.62 ? 2 KXB B C04 1 HETATM 12014 C C05 . KXB R 3 . ? 66.482 70.741 70.399 1.00 32.72 ? 2 KXB B C05 1 HETATM 12015 C C06 . KXB R 3 . ? 66.700 69.528 71.027 1.00 35.26 ? 2 KXB B C06 1 HETATM 12016 C C07 . KXB R 3 . ? 65.772 71.736 71.116 1.00 30.78 ? 2 KXB B C07 1 HETATM 12017 C C08 . KXB R 3 . ? 67.882 71.249 66.475 1.00 33.75 ? 2 KXB B C08 1 HETATM 12018 C C09 . KXB R 3 . ? 66.281 70.383 67.936 1.00 31.48 ? 2 KXB B C09 1 HETATM 12019 C C10 . KXB R 3 . ? 66.220 69.343 72.335 1.00 33.80 ? 2 KXB B C10 1 HETATM 12020 C C11 . KXB R 3 . ? 65.323 71.455 72.414 1.00 29.44 ? 2 KXB B C11 1 HETATM 12021 C C12 . KXB R 3 . ? 66.592 67.975 72.794 1.00 41.78 ? 2 KXB B C12 1 HETATM 12022 C C13 . KXB R 3 . ? 67.398 68.290 70.548 1.00 31.50 ? 2 KXB B C13 1 HETATM 12023 C C14 . KXB R 3 . ? 64.569 72.440 73.246 1.00 33.12 ? 2 KXB B C14 1 HETATM 12024 C C15 . KXB R 3 . ? 66.397 63.733 70.110 1.00 46.44 ? 2 KXB B C15 1 HETATM 12025 C C16 . KXB R 3 . ? 65.501 73.092 70.492 1.00 28.20 ? 2 KXB B C16 1 HETATM 12026 C C17 . KXB R 3 . ? 68.120 66.185 71.849 1.00 42.97 ? 2 KXB B C17 1 HETATM 12027 C C18 . KXB R 3 . ? 68.091 65.322 70.523 1.00 43.02 ? 2 KXB B C18 1 HETATM 12028 N N19 . KXB R 3 . ? 65.544 70.255 73.061 1.00 31.46 ? 2 KXB B N19 1 HETATM 12029 N N20 . KXB R 3 . ? 67.376 67.448 71.739 1.00 39.13 ? 2 KXB B N20 1 HETATM 12030 N N21 . KXB R 3 . ? 64.604 72.939 69.385 1.00 23.65 ? 2 KXB B N21 1 HETATM 12031 O O22 . KXB R 3 . ? 66.336 67.407 73.851 1.00 38.58 ? 2 KXB B O22 1 HETATM 12032 O O23 . KXB R 3 . ? 66.716 65.108 70.201 1.00 50.70 ? 2 KXB B O23 1 HETATM 12033 CL CL1 . KXB R 3 . ? 68.440 71.458 64.887 1.00 35.41 ? 2 KXB B CL1 1 HETATM 12034 CL CL2 . KXB R 3 . ? 64.837 69.481 68.157 1.00 40.44 ? 2 KXB B CL2 1 HETATM 12035 O O . HOH S 4 . ? 56.384 56.066 42.993 1.00 23.54 ? 5 HOH A O 1 HETATM 12036 O O . HOH S 4 . ? 61.242 40.651 27.304 1.00 25.32 ? 7 HOH A O 1 HETATM 12037 O O . HOH S 4 . ? 46.495 55.054 45.613 1.00 24.49 ? 14 HOH A O 1 HETATM 12038 O O . HOH S 4 . ? 33.369 51.352 39.395 1.00 25.92 ? 19 HOH A O 1 HETATM 12039 O O . HOH S 4 . ? 49.461 38.860 22.334 1.00 32.99 ? 20 HOH A O 1 HETATM 12040 O O . HOH S 4 . ? 32.625 50.216 5.190 1.00 29.76 ? 21 HOH A O 1 HETATM 12041 O O . HOH S 4 . ? 46.833 32.093 21.247 1.00 30.95 ? 24 HOH A O 1 HETATM 12042 O O . HOH S 4 . ? 36.111 50.210 33.070 1.00 30.39 ? 25 HOH A O 1 HETATM 12043 O O . HOH S 4 . ? 50.891 57.621 36.776 1.00 25.82 ? 26 HOH A O 1 HETATM 12044 O O . HOH S 4 . ? 42.963 35.260 29.331 1.00 29.80 ? 27 HOH A O 1 HETATM 12045 O O . HOH S 4 . ? 36.154 46.293 19.328 1.00 28.29 ? 28 HOH A O 1 HETATM 12046 O O . HOH S 4 . ? 43.008 44.917 50.104 1.00 26.85 ? 30 HOH A O 1 HETATM 12047 O O . HOH S 4 . ? 29.303 59.102 39.715 1.00 30.41 ? 32 HOH A O 1 HETATM 12048 O O . HOH S 4 . ? 56.360 44.878 37.481 1.00 28.66 ? 33 HOH A O 1 HETATM 12049 O O . HOH S 4 . ? 51.912 60.215 47.315 1.00 25.85 ? 790 HOH A O 1 HETATM 12050 O O . HOH S 4 . ? 45.171 61.123 35.613 1.00 24.62 ? 791 HOH A O 1 HETATM 12051 O O . HOH S 4 . ? 56.674 37.095 10.036 1.00 31.34 ? 792 HOH A O 1 HETATM 12052 O O . HOH S 4 . ? 52.643 53.345 35.028 1.00 24.03 ? 793 HOH A O 1 HETATM 12053 O O . HOH S 4 . ? 49.638 61.897 51.540 1.00 26.66 ? 794 HOH A O 1 HETATM 12054 O O . HOH S 4 . ? 40.796 65.251 39.294 1.00 27.57 ? 795 HOH A O 1 HETATM 12055 O O . HOH S 4 . ? 30.175 56.600 39.061 1.00 28.06 ? 796 HOH A O 1 HETATM 12056 O O . HOH S 4 . ? 54.167 73.526 54.371 1.00 27.59 ? 797 HOH A O 1 HETATM 12057 O O . HOH S 4 . ? 38.321 64.934 17.490 1.00 34.40 ? 798 HOH A O 1 HETATM 12058 O O . HOH S 4 . ? 29.232 40.986 4.142 1.00 37.13 ? 799 HOH A O 1 HETATM 12059 O O . HOH S 4 . ? 64.608 62.366 44.200 1.00 28.32 ? 800 HOH A O 1 HETATM 12060 O O . HOH S 4 . ? 30.832 59.309 36.144 1.00 31.05 ? 801 HOH A O 1 HETATM 12061 O O . HOH S 4 . ? 43.226 35.156 13.270 1.00 31.18 ? 802 HOH A O 1 HETATM 12062 O O . HOH S 4 . ? 61.274 72.585 50.271 1.00 26.74 ? 803 HOH A O 1 HETATM 12063 O O . HOH S 4 . ? 46.688 29.269 28.394 1.00 34.98 ? 804 HOH A O 1 HETATM 12064 O O . HOH S 4 . ? 46.662 46.441 35.006 1.00 32.83 ? 805 HOH A O 1 HETATM 12065 O O . HOH S 4 . ? 39.213 62.047 39.706 1.00 25.55 ? 806 HOH A O 1 HETATM 12066 O O . HOH S 4 . ? 33.917 53.501 13.373 1.00 32.88 ? 807 HOH A O 1 HETATM 12067 O O . HOH S 4 . ? 33.240 33.280 18.247 1.00 30.30 ? 808 HOH A O 1 HETATM 12068 O O . HOH S 4 . ? 56.867 64.941 47.133 1.00 28.95 ? 809 HOH A O 1 HETATM 12069 O O . HOH S 4 . ? 52.701 62.071 -3.914 1.00 29.49 ? 810 HOH A O 1 HETATM 12070 O O . HOH S 4 . ? 63.714 44.599 33.402 1.00 25.78 ? 811 HOH A O 1 HETATM 12071 O O . HOH S 4 . ? 56.546 64.710 40.100 1.00 34.42 ? 812 HOH A O 1 HETATM 12072 O O . HOH S 4 . ? 50.652 66.273 11.841 1.00 33.74 ? 813 HOH A O 1 HETATM 12073 O O . HOH S 4 . ? 49.647 31.957 30.373 1.00 29.37 ? 814 HOH A O 1 HETATM 12074 O O . HOH S 4 . ? 49.987 50.231 58.827 1.00 25.62 ? 815 HOH A O 1 HETATM 12075 O O . HOH S 4 . ? 63.516 42.144 55.312 1.00 32.54 ? 816 HOH A O 1 HETATM 12076 O O . HOH S 4 . ? 27.292 45.503 6.750 1.00 36.03 ? 817 HOH A O 1 HETATM 12077 O O . HOH S 4 . ? 33.705 41.161 28.269 1.00 31.43 ? 818 HOH A O 1 HETATM 12078 O O . HOH S 4 . ? 57.267 53.041 59.200 1.00 27.66 ? 819 HOH A O 1 HETATM 12079 O O . HOH S 4 . ? 34.163 40.650 0.743 1.00 29.73 ? 820 HOH A O 1 HETATM 12080 O O . HOH S 4 . ? 51.205 63.691 30.429 1.00 29.16 ? 821 HOH A O 1 HETATM 12081 O O . HOH S 4 . ? 47.378 59.694 35.010 1.00 27.19 ? 822 HOH A O 1 HETATM 12082 O O . HOH S 4 . ? 43.003 64.874 34.590 1.00 29.12 ? 823 HOH A O 1 HETATM 12083 O O . HOH S 4 . ? 64.889 47.104 62.374 1.00 25.77 ? 824 HOH A O 1 HETATM 12084 O O . HOH S 4 . ? 47.633 37.370 36.690 1.00 30.86 ? 825 HOH A O 1 HETATM 12085 O O . HOH S 4 . ? 41.848 38.701 27.094 1.00 30.80 ? 826 HOH A O 1 HETATM 12086 O O . HOH S 4 . ? 18.740 56.570 17.143 1.00 51.35 ? 827 HOH A O 1 HETATM 12087 O O . HOH S 4 . ? 77.430 46.721 34.743 1.00 27.90 ? 828 HOH A O 1 HETATM 12088 O O . HOH S 4 . ? 35.985 50.358 0.942 1.00 37.47 ? 829 HOH A O 1 HETATM 12089 O O . HOH S 4 . ? 35.676 40.843 30.752 1.00 34.24 ? 830 HOH A O 1 HETATM 12090 O O . HOH S 4 . ? 63.864 47.897 32.847 1.00 33.97 ? 831 HOH A O 1 HETATM 12091 O O . HOH S 4 . ? 44.964 32.344 23.168 1.00 30.35 ? 832 HOH A O 1 HETATM 12092 O O . HOH S 4 . ? 28.244 77.114 29.809 1.00 37.44 ? 833 HOH A O 1 HETATM 12093 O O . HOH S 4 . ? 48.887 57.763 11.139 1.00 30.53 ? 834 HOH A O 1 HETATM 12094 O O . HOH S 4 . ? 41.771 43.829 33.155 1.00 27.18 ? 835 HOH A O 1 HETATM 12095 O O . HOH S 4 . ? 58.960 60.971 38.381 1.00 34.72 ? 836 HOH A O 1 HETATM 12096 O O . HOH S 4 . ? 52.464 75.416 30.096 1.00 32.77 ? 837 HOH A O 1 HETATM 12097 O O . HOH S 4 . ? 53.732 38.712 35.879 1.00 27.55 ? 838 HOH A O 1 HETATM 12098 O O . HOH S 4 . ? 39.150 37.107 27.649 1.00 33.75 ? 839 HOH A O 1 HETATM 12099 O O . HOH S 4 . ? 29.418 33.366 1.638 1.00 39.98 ? 840 HOH A O 1 HETATM 12100 O O . HOH S 4 . ? 57.545 34.810 53.901 1.00 34.72 ? 841 HOH A O 1 HETATM 12101 O O . HOH S 4 . ? 57.483 44.125 9.333 1.00 28.10 ? 842 HOH A O 1 HETATM 12102 O O . HOH S 4 . ? 52.346 59.366 38.784 1.00 29.90 ? 843 HOH A O 1 HETATM 12103 O O . HOH S 4 . ? 45.530 52.213 11.518 1.00 36.06 ? 844 HOH A O 1 HETATM 12104 O O . HOH S 4 . ? 59.934 33.262 50.716 1.00 33.89 ? 845 HOH A O 1 HETATM 12105 O O . HOH S 4 . ? 41.020 77.747 12.993 1.00 35.79 ? 846 HOH A O 1 HETATM 12106 O O . HOH S 4 . ? 29.138 58.344 43.736 1.00 35.30 ? 847 HOH A O 1 HETATM 12107 O O . HOH S 4 . ? 50.479 33.950 17.813 1.00 29.61 ? 848 HOH A O 1 HETATM 12108 O O . HOH S 4 . ? 25.569 48.622 7.222 1.00 34.57 ? 849 HOH A O 1 HETATM 12109 O O . HOH S 4 . ? 50.189 44.430 18.369 1.00 30.79 ? 850 HOH A O 1 HETATM 12110 O O . HOH S 4 . ? 52.236 41.017 25.108 1.00 25.24 ? 852 HOH A O 1 HETATM 12111 O O . HOH S 4 . ? 28.576 51.427 3.450 1.00 34.20 ? 853 HOH A O 1 HETATM 12112 O O . HOH S 4 . ? 64.711 64.115 33.610 1.00 36.88 ? 854 HOH A O 1 HETATM 12113 O O . HOH S 4 . ? 45.757 55.732 30.786 1.00 26.61 ? 855 HOH A O 1 HETATM 12114 O O . HOH S 4 . ? 59.029 32.822 53.092 1.00 36.20 ? 856 HOH A O 1 HETATM 12115 O O . HOH S 4 . ? 36.201 33.295 10.394 1.00 38.89 ? 857 HOH A O 1 HETATM 12116 O O . HOH S 4 . ? 66.744 64.632 36.526 1.00 40.87 ? 858 HOH A O 1 HETATM 12117 O O . HOH S 4 . ? 64.837 41.505 28.700 1.00 32.85 ? 859 HOH A O 1 HETATM 12118 O O . HOH S 4 . ? 49.629 59.925 36.690 1.00 33.39 ? 860 HOH A O 1 HETATM 12119 O O . HOH S 4 . ? 52.961 42.060 2.157 1.00 33.34 ? 861 HOH A O 1 HETATM 12120 O O . HOH S 4 . ? 49.121 35.266 15.925 1.00 32.77 ? 862 HOH A O 1 HETATM 12121 O O . HOH S 4 . ? 32.351 47.549 5.467 1.00 32.61 ? 863 HOH A O 1 HETATM 12122 O O . HOH S 4 . ? 37.892 79.944 30.328 1.00 37.48 ? 864 HOH A O 1 HETATM 12123 O O . HOH S 4 . ? 51.223 68.277 52.857 1.00 34.87 ? 865 HOH A O 1 HETATM 12124 O O . HOH S 4 . ? 55.840 36.937 36.420 1.00 27.51 ? 866 HOH A O 1 HETATM 12125 O O . HOH S 4 . ? 24.497 40.193 12.886 1.00 36.65 ? 867 HOH A O 1 HETATM 12126 O O . HOH S 4 . ? 21.330 59.120 11.214 1.00 44.04 ? 868 HOH A O 1 HETATM 12127 O O . HOH S 4 . ? 66.965 71.582 44.490 1.00 33.25 ? 869 HOH A O 1 HETATM 12128 O O . HOH S 4 . ? 44.944 64.986 6.240 1.00 36.56 ? 870 HOH A O 1 HETATM 12129 O O . HOH S 4 . ? 59.693 63.610 -5.425 1.00 37.23 ? 871 HOH A O 1 HETATM 12130 O O . HOH S 4 . ? 51.290 38.217 34.191 1.00 33.24 ? 872 HOH A O 1 HETATM 12131 O O . HOH S 4 . ? 19.982 53.918 21.418 1.00 46.33 ? 873 HOH A O 1 HETATM 12132 O O . HOH S 4 . ? 38.081 74.322 7.836 1.00 39.74 ? 874 HOH A O 1 HETATM 12133 O O . HOH S 4 . ? 68.744 43.985 11.219 1.00 39.57 ? 875 HOH A O 1 HETATM 12134 O O . HOH S 4 . ? 52.383 33.944 26.289 1.00 30.71 ? 876 HOH A O 1 HETATM 12135 O O . HOH S 4 . ? 61.394 52.000 34.862 1.00 30.04 ? 877 HOH A O 1 HETATM 12136 O O . HOH S 4 . ? 39.775 51.225 20.988 1.00 40.16 ? 878 HOH A O 1 HETATM 12137 O O . HOH S 4 . ? 53.957 54.977 12.662 1.00 36.11 ? 879 HOH A O 1 HETATM 12138 O O . HOH S 4 . ? 50.316 34.124 28.502 1.00 32.14 ? 880 HOH A O 1 HETATM 12139 O O . HOH S 4 . ? 29.680 41.517 7.180 1.00 37.32 ? 881 HOH A O 1 HETATM 12140 O O . HOH S 4 . ? 57.455 33.581 50.099 1.00 32.73 ? 882 HOH A O 1 HETATM 12141 O O . HOH S 4 . ? 28.979 67.406 34.633 1.00 35.03 ? 883 HOH A O 1 HETATM 12142 O O . HOH S 4 . ? 70.866 48.635 47.781 1.00 32.50 ? 884 HOH A O 1 HETATM 12143 O O . HOH S 4 . ? 27.797 48.976 3.477 1.00 40.64 ? 885 HOH A O 1 HETATM 12144 O O . HOH S 4 . ? 34.728 59.447 16.908 1.00 33.62 ? 886 HOH A O 1 HETATM 12145 O O . HOH S 4 . ? 30.190 79.220 12.585 1.00 52.05 ? 887 HOH A O 1 HETATM 12146 O O . HOH S 4 . ? 50.947 55.648 12.180 1.00 31.14 ? 888 HOH A O 1 HETATM 12147 O O . HOH S 4 . ? 52.079 60.692 35.931 1.00 38.76 ? 889 HOH A O 1 HETATM 12148 O O . HOH S 4 . ? 68.603 51.880 27.138 1.00 35.10 ? 890 HOH A O 1 HETATM 12149 O O . HOH S 4 . ? 42.180 50.591 33.811 1.00 29.44 ? 891 HOH A O 1 HETATM 12150 O O . HOH S 4 . ? 47.436 44.018 28.805 1.00 42.63 ? 892 HOH A O 1 HETATM 12151 O O . HOH S 4 . ? 51.800 77.857 28.621 1.00 34.78 ? 893 HOH A O 1 HETATM 12152 O O . HOH S 4 . ? 22.480 42.740 14.897 1.00 38.71 ? 894 HOH A O 1 HETATM 12153 O O . HOH S 4 . ? 50.739 56.777 -3.055 1.00 41.32 ? 895 HOH A O 1 HETATM 12154 O O . HOH S 4 . ? 30.744 56.770 8.250 1.00 39.31 ? 896 HOH A O 1 HETATM 12155 O O . HOH S 4 . ? 71.240 50.282 25.380 1.00 39.94 ? 897 HOH A O 1 HETATM 12156 O O . HOH S 4 . ? 60.634 57.557 13.580 1.00 40.81 ? 898 HOH A O 1 HETATM 12157 O O . HOH S 4 . ? 36.691 81.938 14.514 1.00 42.36 ? 899 HOH A O 1 HETATM 12158 O O . HOH S 4 . ? 48.919 44.905 -3.708 1.00 41.90 ? 900 HOH A O 1 HETATM 12159 O O . HOH S 4 . ? 64.601 56.239 15.390 1.00 38.52 ? 901 HOH A O 1 HETATM 12160 O O . HOH S 4 . ? 66.727 50.455 7.226 1.00 40.19 ? 902 HOH A O 1 HETATM 12161 O O . HOH S 4 . ? 29.099 65.988 10.877 1.00 39.17 ? 903 HOH A O 1 HETATM 12162 O O . HOH S 4 . ? 37.590 49.903 53.536 1.00 45.38 ? 904 HOH A O 1 HETATM 12163 O O . HOH S 4 . ? 71.266 59.395 39.843 1.00 32.33 ? 905 HOH A O 1 HETATM 12164 O O . HOH S 4 . ? 44.478 43.573 1.739 1.00 35.89 ? 906 HOH A O 1 HETATM 12165 O O . HOH S 4 . ? 36.274 57.263 23.461 1.00 37.94 ? 907 HOH A O 1 HETATM 12166 O O . HOH S 4 . ? 57.543 61.380 12.112 1.00 41.53 ? 908 HOH A O 1 HETATM 12167 O O . HOH S 4 . ? 47.494 28.819 25.626 1.00 39.72 ? 909 HOH A O 1 HETATM 12168 O O . HOH S 4 . ? 63.266 47.921 24.828 1.00 34.08 ? 910 HOH A O 1 HETATM 12169 O O . HOH S 4 . ? 32.714 63.232 49.521 1.00 38.15 ? 911 HOH A O 1 HETATM 12170 O O . HOH S 4 . ? 31.787 41.453 52.661 1.00 39.12 ? 912 HOH A O 1 HETATM 12171 O O . HOH S 4 . ? 52.780 63.124 38.805 1.00 31.62 ? 913 HOH A O 1 HETATM 12172 O O . HOH S 4 . ? 35.683 27.254 27.096 1.00 43.77 ? 914 HOH A O 1 HETATM 12173 O O . HOH S 4 . ? 57.856 54.743 1.518 1.00 35.46 ? 915 HOH A O 1 HETATM 12174 O O . HOH S 4 . ? 40.645 32.370 11.715 1.00 44.06 ? 916 HOH A O 1 HETATM 12175 O O . HOH S 4 . ? 46.182 48.561 33.653 1.00 39.80 ? 917 HOH A O 1 HETATM 12176 O O . HOH S 4 . ? 49.555 47.918 32.087 1.00 38.16 ? 918 HOH A O 1 HETATM 12177 O O . HOH S 4 . ? 52.541 46.550 32.414 1.00 48.74 ? 919 HOH A O 1 HETATM 12178 O O . HOH S 4 . ? 48.483 44.800 31.720 1.00 38.56 ? 920 HOH A O 1 HETATM 12179 O O . HOH S 4 . ? 51.549 43.259 31.467 1.00 38.72 ? 921 HOH A O 1 HETATM 12180 O O . HOH S 4 . ? 46.905 54.068 29.128 1.00 35.02 ? 922 HOH A O 1 HETATM 12181 O O . HOH S 4 . ? 49.242 52.746 30.147 1.00 39.02 ? 923 HOH A O 1 HETATM 12182 O O . HOH S 4 . ? 52.749 56.114 30.326 1.00 37.50 ? 924 HOH A O 1 HETATM 12183 O O . HOH S 4 . ? 53.325 56.844 35.249 1.00 40.26 ? 925 HOH A O 1 HETATM 12184 O O . HOH S 4 . ? 55.484 44.135 29.352 1.00 41.96 ? 926 HOH A O 1 HETATM 12185 O O . HOH S 4 . ? 58.905 44.383 36.682 1.00 41.85 ? 927 HOH A O 1 HETATM 12186 O O . HOH S 4 . ? 59.559 46.379 34.632 1.00 43.44 ? 928 HOH A O 1 HETATM 12187 O O . HOH S 4 . ? 37.586 54.867 25.382 1.00 46.64 ? 929 HOH A O 1 HETATM 12188 O O . HOH S 4 . ? 37.041 52.417 31.854 1.00 36.74 ? 930 HOH A O 1 HETATM 12189 O O . HOH S 4 . ? 39.115 46.990 18.665 1.00 17.12 ? 931 HOH A O 1 HETATM 12190 O O . HOH S 4 . ? 47.591 68.571 26.273 1.00 36.68 ? 932 HOH A O 1 HETATM 12191 O O . HOH S 4 . ? 63.192 45.247 63.539 1.00 30.61 ? 933 HOH A O 1 HETATM 12192 O O . HOH S 4 . ? 62.344 45.954 65.998 1.00 33.92 ? 934 HOH A O 1 HETATM 12193 O O . HOH S 4 . ? 50.366 59.799 49.935 1.00 29.16 ? 935 HOH A O 1 HETATM 12194 O O . HOH S 4 . ? 72.547 57.212 39.942 1.00 31.37 ? 936 HOH A O 1 HETATM 12195 O O . HOH S 4 . ? 48.019 46.081 17.813 1.00 29.63 ? 937 HOH A O 1 HETATM 12196 O O . HOH S 4 . ? 32.770 44.961 25.323 1.00 39.59 ? 938 HOH A O 1 HETATM 12197 O O . HOH S 4 . ? 27.034 60.652 36.241 1.00 32.91 ? 939 HOH A O 1 HETATM 12198 O O . HOH S 4 . ? 53.121 59.216 34.113 1.00 43.90 ? 940 HOH A O 1 HETATM 12199 O O . HOH S 4 . ? 27.288 58.632 37.931 1.00 32.42 ? 941 HOH A O 1 HETATM 12200 O O . HOH S 4 . ? 30.605 53.988 21.371 1.00 34.08 ? 942 HOH A O 1 HETATM 12201 O O . HOH S 4 . ? 61.304 37.682 32.027 1.00 29.38 ? 943 HOH A O 1 HETATM 12202 O O . HOH S 4 . ? 66.482 50.397 26.620 1.00 38.15 ? 944 HOH A O 1 HETATM 12203 O O . HOH S 4 . ? 29.763 34.693 5.329 1.00 39.88 ? 945 HOH A O 1 HETATM 12204 O O . HOH S 4 . ? 37.583 32.356 12.523 1.00 37.35 ? 946 HOH A O 1 HETATM 12205 O O . HOH S 4 . ? 53.115 70.144 52.323 1.00 36.13 ? 947 HOH A O 1 HETATM 12206 O O . HOH S 4 . ? 57.962 41.564 8.776 1.00 31.65 ? 948 HOH A O 1 HETATM 12207 O O . HOH S 4 . ? 47.214 31.412 11.698 1.00 39.56 ? 949 HOH A O 1 HETATM 12208 O O . HOH S 4 . ? 61.584 40.277 32.114 1.00 33.22 ? 950 HOH A O 1 HETATM 12209 O O . HOH S 4 . ? 47.296 68.474 21.514 1.00 35.36 ? 951 HOH A O 1 HETATM 12210 O O . HOH S 4 . ? 56.359 63.143 51.727 1.00 36.39 ? 952 HOH A O 1 HETATM 12211 O O . HOH S 4 . ? 47.791 87.628 12.209 1.00 56.64 ? 953 HOH A O 1 HETATM 12212 O O . HOH S 4 . ? 42.028 75.480 35.616 1.00 41.05 ? 954 HOH A O 1 HETATM 12213 O O . HOH S 4 . ? 30.696 65.147 42.487 1.00 37.51 ? 955 HOH A O 1 HETATM 12214 O O . HOH S 4 . ? 67.069 40.278 14.291 1.00 34.53 ? 956 HOH A O 1 HETATM 12215 O O . HOH S 4 . ? 52.969 32.479 24.127 1.00 37.97 ? 957 HOH A O 1 HETATM 12216 O O . HOH S 4 . ? 32.457 40.810 25.797 1.00 33.93 ? 958 HOH A O 1 HETATM 12217 O O . HOH S 4 . ? 55.212 34.891 12.978 1.00 41.65 ? 959 HOH A O 1 HETATM 12218 O O . HOH S 4 . ? 65.801 31.232 47.324 1.00 35.43 ? 960 HOH A O 1 HETATM 12219 O O . HOH S 4 . ? 44.155 37.437 49.750 1.00 42.67 ? 961 HOH A O 1 HETATM 12220 O O . HOH S 4 . ? 57.868 79.223 51.065 1.00 26.99 ? 962 HOH A O 1 HETATM 12221 O O . HOH S 4 . ? 38.868 62.573 22.444 1.00 38.77 ? 963 HOH A O 1 HETATM 12222 O O . HOH S 4 . ? 40.539 30.599 29.505 1.00 35.62 ? 964 HOH A O 1 HETATM 12223 O O . HOH S 4 . ? 52.447 66.208 42.081 1.00 37.62 ? 965 HOH A O 1 HETATM 12224 O O . HOH S 4 . ? 64.287 55.207 11.034 1.00 41.42 ? 966 HOH A O 1 HETATM 12225 O O . HOH S 4 . ? 50.360 34.729 38.200 1.00 35.52 ? 967 HOH A O 1 HETATM 12226 O O . HOH S 4 . ? 39.343 61.117 24.453 1.00 34.67 ? 968 HOH A O 1 HETATM 12227 O O . HOH S 4 . ? 54.750 45.452 17.225 1.00 35.52 ? 969 HOH A O 1 HETATM 12228 O O . HOH S 4 . ? 28.974 60.215 42.143 1.00 37.23 ? 970 HOH A O 1 HETATM 12229 O O . HOH S 4 . ? 28.335 36.091 24.049 1.00 39.91 ? 971 HOH A O 1 HETATM 12230 O O . HOH S 4 . ? 66.007 40.132 56.811 1.00 38.77 ? 972 HOH A O 1 HETATM 12231 O O . HOH S 4 . ? 46.669 82.017 30.884 1.00 38.66 ? 973 HOH A O 1 HETATM 12232 O O . HOH S 4 . ? 62.611 64.526 41.821 1.00 36.68 ? 974 HOH A O 1 HETATM 12233 O O . HOH S 4 . ? 43.095 47.347 56.387 1.00 44.23 ? 975 HOH A O 1 HETATM 12234 O O . HOH S 4 . ? 74.855 48.681 41.076 1.00 37.10 ? 976 HOH A O 1 HETATM 12235 O O . HOH S 4 . ? 38.772 65.863 50.741 1.00 33.85 ? 977 HOH A O 1 HETATM 12236 O O . HOH S 4 . ? 47.841 63.131 -0.070 1.00 43.61 ? 978 HOH A O 1 HETATM 12237 O O . HOH S 4 . ? 77.581 36.454 31.034 1.00 43.33 ? 979 HOH A O 1 HETATM 12238 O O . HOH S 4 . ? 72.259 46.591 49.032 1.00 39.40 ? 980 HOH A O 1 HETATM 12239 O O . HOH S 4 . ? 46.598 38.779 52.884 1.00 35.54 ? 981 HOH A O 1 HETATM 12240 O O . HOH S 4 . ? 35.998 40.014 -1.990 1.00 35.27 ? 982 HOH A O 1 HETATM 12241 O O . HOH S 4 . ? 30.205 45.711 6.621 1.00 34.09 ? 983 HOH A O 1 HETATM 12242 O O . HOH S 4 . ? 41.093 71.565 36.725 1.00 37.93 ? 984 HOH A O 1 HETATM 12243 O O . HOH S 4 . ? 54.528 63.412 49.836 1.00 34.93 ? 985 HOH A O 1 HETATM 12244 O O . HOH S 4 . ? 65.254 35.526 57.077 1.00 47.29 ? 986 HOH A O 1 HETATM 12245 O O . HOH S 4 . ? 68.052 51.793 51.358 1.00 34.07 ? 987 HOH A O 1 HETATM 12246 O O . HOH S 4 . ? 61.459 68.616 42.685 1.00 32.96 ? 988 HOH A O 1 HETATM 12247 O O . HOH S 4 . ? 36.704 67.896 44.672 1.00 36.53 ? 989 HOH A O 1 HETATM 12248 O O . HOH S 4 . ? 56.942 69.116 32.672 1.00 42.72 ? 990 HOH A O 1 HETATM 12249 O O . HOH S 4 . ? 49.185 82.025 16.641 1.00 48.40 ? 991 HOH A O 1 HETATM 12250 O O . HOH S 4 . ? 16.500 55.249 28.295 1.00 42.73 ? 992 HOH A O 1 HETATM 12251 O O . HOH S 4 . ? 40.240 44.708 23.708 1.00 39.26 ? 993 HOH A O 1 HETATM 12252 O O . HOH S 4 . ? 26.450 38.119 8.552 1.00 37.43 ? 994 HOH A O 1 HETATM 12253 O O . HOH T 4 . ? 80.824 63.348 96.050 1.00 32.61 ? 1 HOH B O 1 HETATM 12254 O O . HOH T 4 . ? 62.118 62.260 62.852 1.00 22.73 ? 3 HOH B O 1 HETATM 12255 O O . HOH T 4 . ? 64.961 85.494 66.424 1.00 28.65 ? 4 HOH B O 1 HETATM 12256 O O . HOH T 4 . ? 57.653 71.068 70.871 1.00 25.23 ? 8 HOH B O 1 HETATM 12257 O O . HOH T 4 . ? 72.045 76.256 55.861 1.00 28.53 ? 11 HOH B O 1 HETATM 12258 O O . HOH T 4 . ? 77.637 58.559 78.971 1.00 26.55 ? 12 HOH B O 1 HETATM 12259 O O . HOH T 4 . ? 73.855 55.963 72.662 1.00 29.52 ? 13 HOH B O 1 HETATM 12260 O O . HOH T 4 . ? 51.509 79.655 88.189 1.00 29.95 ? 15 HOH B O 1 HETATM 12261 O O . HOH T 4 . ? 81.002 64.082 69.597 1.00 28.47 ? 16 HOH B O 1 HETATM 12262 O O . HOH T 4 . ? 64.309 66.143 71.026 1.00 25.75 ? 17 HOH B O 1 HETATM 12263 O O . HOH T 4 . ? 53.108 61.189 58.874 1.00 27.39 ? 18 HOH B O 1 HETATM 12264 O O . HOH T 4 . ? 56.080 73.050 70.112 1.00 24.90 ? 22 HOH B O 1 HETATM 12265 O O . HOH T 4 . ? 62.332 72.172 60.471 1.00 25.08 ? 23 HOH B O 1 HETATM 12266 O O . HOH T 4 . ? 55.833 68.348 54.447 1.00 31.51 ? 29 HOH B O 1 HETATM 12267 O O . HOH T 4 . ? 65.139 61.428 46.844 1.00 24.67 ? 31 HOH B O 1 HETATM 12268 O O . HOH T 4 . ? 51.046 67.046 93.850 1.00 33.62 ? 34 HOH B O 1 HETATM 12269 O O . HOH T 4 . ? 73.124 69.384 87.628 1.00 28.52 ? 35 HOH B O 1 HETATM 12270 O O . HOH T 4 . ? 59.950 67.553 69.016 1.00 29.83 ? 36 HOH B O 1 HETATM 12271 O O . HOH T 4 . ? 38.761 88.867 75.815 1.00 33.02 ? 790 HOH B O 1 HETATM 12272 O O . HOH T 4 . ? 81.799 76.884 92.776 1.00 29.57 ? 791 HOH B O 1 HETATM 12273 O O . HOH T 4 . ? 39.788 65.179 77.025 1.00 30.48 ? 792 HOH B O 1 HETATM 12274 O O . HOH T 4 . ? 73.280 62.901 68.718 1.00 27.36 ? 793 HOH B O 1 HETATM 12275 O O . HOH T 4 . ? 81.652 77.125 76.760 1.00 27.19 ? 794 HOH B O 1 HETATM 12276 O O . HOH T 4 . ? 51.741 93.563 76.009 1.00 31.30 ? 795 HOH B O 1 HETATM 12277 O O . HOH T 4 . ? 45.992 56.004 55.670 1.00 28.70 ? 796 HOH B O 1 HETATM 12278 O O . HOH T 4 . ? 57.453 66.460 58.704 1.00 27.21 ? 797 HOH B O 1 HETATM 12279 O O . HOH T 4 . ? 76.530 56.383 50.908 1.00 33.09 ? 798 HOH B O 1 HETATM 12280 O O . HOH T 4 . ? 70.022 83.235 86.821 1.00 28.01 ? 799 HOH B O 1 HETATM 12281 O O . HOH T 4 . ? 43.766 73.862 97.634 1.00 51.80 ? 800 HOH B O 1 HETATM 12282 O O . HOH T 4 . ? 74.630 90.276 101.863 1.00 37.67 ? 801 HOH B O 1 HETATM 12283 O O . HOH T 4 . ? 64.419 73.183 102.679 1.00 40.27 ? 802 HOH B O 1 HETATM 12284 O O . HOH T 4 . ? 57.930 68.059 55.902 1.00 25.54 ? 803 HOH B O 1 HETATM 12285 O O . HOH T 4 . ? 54.778 78.905 66.325 1.00 28.63 ? 804 HOH B O 1 HETATM 12286 O O . HOH T 4 . ? 66.335 82.874 72.915 1.00 30.78 ? 805 HOH B O 1 HETATM 12287 O O . HOH T 4 . ? 42.303 64.771 75.629 1.00 29.35 ? 806 HOH B O 1 HETATM 12288 O O . HOH T 4 . ? 53.458 94.910 74.434 1.00 32.99 ? 807 HOH B O 1 HETATM 12289 O O . HOH T 4 . ? 85.401 70.647 75.790 1.00 29.66 ? 808 HOH B O 1 HETATM 12290 O O . HOH T 4 . ? 80.159 79.536 102.849 1.00 35.38 ? 809 HOH B O 1 HETATM 12291 O O . HOH T 4 . ? 68.242 49.792 91.669 1.00 33.11 ? 810 HOH B O 1 HETATM 12292 O O . HOH T 4 . ? 51.695 69.192 84.191 1.00 42.78 ? 811 HOH B O 1 HETATM 12293 O O . HOH T 4 . ? 52.154 74.948 71.514 1.00 26.72 ? 812 HOH B O 1 HETATM 12294 O O . HOH T 4 . ? 36.504 68.582 86.926 1.00 34.72 ? 813 HOH B O 1 HETATM 12295 O O . HOH T 4 . ? 79.206 66.231 70.169 1.00 25.17 ? 814 HOH B O 1 HETATM 12296 O O . HOH T 4 . ? 71.802 54.367 43.587 1.00 28.37 ? 815 HOH B O 1 HETATM 12297 O O . HOH T 4 . ? 53.716 66.615 75.393 1.00 30.97 ? 816 HOH B O 1 HETATM 12298 O O . HOH T 4 . ? 56.769 83.673 89.236 1.00 29.74 ? 817 HOH B O 1 HETATM 12299 O O . HOH T 4 . ? 55.346 78.865 81.402 1.00 34.87 ? 818 HOH B O 1 HETATM 12300 O O . HOH T 4 . ? 34.626 76.238 80.719 1.00 43.55 ? 819 HOH B O 1 HETATM 12301 O O . HOH T 4 . ? 79.499 80.576 78.482 1.00 33.58 ? 820 HOH B O 1 HETATM 12302 O O . HOH T 4 . ? 56.877 89.055 66.258 1.00 31.51 ? 821 HOH B O 1 HETATM 12303 O O . HOH T 4 . ? 54.863 91.212 69.660 1.00 33.24 ? 822 HOH B O 1 HETATM 12304 O O . HOH T 4 . ? 66.172 76.802 72.128 1.00 28.87 ? 823 HOH B O 1 HETATM 12305 O O . HOH T 4 . ? 56.840 87.332 69.977 1.00 31.09 ? 824 HOH B O 1 HETATM 12306 O O . HOH T 4 . ? 70.600 55.536 73.266 1.00 36.58 ? 825 HOH B O 1 HETATM 12307 O O . HOH T 4 . ? 46.257 70.349 61.505 1.00 37.10 ? 826 HOH B O 1 HETATM 12308 O O . HOH T 4 . ? 69.635 71.354 90.637 1.00 33.05 ? 827 HOH B O 1 HETATM 12309 O O . HOH T 4 . ? 73.023 77.723 72.735 1.00 26.44 ? 828 HOH B O 1 HETATM 12310 O O . HOH T 4 . ? 35.190 69.879 74.452 1.00 35.47 ? 829 HOH B O 1 HETATM 12311 O O . HOH T 4 . ? 72.255 70.377 109.636 1.00 39.26 ? 830 HOH B O 1 HETATM 12312 O O . HOH T 4 . ? 57.608 89.129 62.079 1.00 36.82 ? 831 HOH B O 1 HETATM 12313 O O . HOH T 4 . ? 74.961 87.488 80.162 1.00 35.38 ? 832 HOH B O 1 HETATM 12314 O O . HOH T 4 . ? 59.927 52.289 58.733 1.00 29.77 ? 833 HOH B O 1 HETATM 12315 O O . HOH T 4 . ? 51.799 65.394 64.035 1.00 32.72 ? 834 HOH B O 1 HETATM 12316 O O . HOH T 4 . ? 60.429 57.976 92.410 1.00 36.49 ? 835 HOH B O 1 HETATM 12317 O O . HOH T 4 . ? 81.059 89.016 78.132 1.00 43.18 ? 836 HOH B O 1 HETATM 12318 O O . HOH T 4 . ? 65.897 86.829 100.731 1.00 32.08 ? 837 HOH B O 1 HETATM 12319 O O . HOH T 4 . ? 76.215 61.649 97.348 1.00 31.21 ? 838 HOH B O 1 HETATM 12320 O O . HOH T 4 . ? 75.048 86.173 77.707 1.00 36.29 ? 839 HOH B O 1 HETATM 12321 O O . HOH T 4 . ? 66.529 93.725 98.735 1.00 35.02 ? 840 HOH B O 1 HETATM 12322 O O . HOH T 4 . ? 83.530 68.138 79.834 1.00 32.04 ? 841 HOH B O 1 HETATM 12323 O O . HOH T 4 . ? 68.560 87.017 100.456 1.00 37.51 ? 842 HOH B O 1 HETATM 12324 O O . HOH T 4 . ? 67.594 68.904 47.173 1.00 34.38 ? 843 HOH B O 1 HETATM 12325 O O . HOH T 4 . ? 64.052 56.527 70.050 1.00 32.24 ? 844 HOH B O 1 HETATM 12326 O O . HOH T 4 . ? 83.561 69.741 88.211 1.00 29.50 ? 845 HOH B O 1 HETATM 12327 O O . HOH T 4 . ? 86.440 48.765 80.126 1.00 35.59 ? 846 HOH B O 1 HETATM 12328 O O . HOH T 4 . ? 81.812 70.883 90.185 1.00 30.09 ? 847 HOH B O 1 HETATM 12329 O O . HOH T 4 . ? 84.557 75.421 83.026 1.00 32.41 ? 848 HOH B O 1 HETATM 12330 O O . HOH T 4 . ? 64.808 84.296 100.407 1.00 41.21 ? 849 HOH B O 1 HETATM 12331 O O . HOH T 4 . ? 40.283 72.803 74.098 1.00 29.68 ? 850 HOH B O 1 HETATM 12332 O O . HOH T 4 . ? 81.279 70.103 69.964 1.00 29.58 ? 852 HOH B O 1 HETATM 12333 O O . HOH T 4 . ? 54.642 65.298 67.210 1.00 33.43 ? 853 HOH B O 1 HETATM 12334 O O . HOH T 4 . ? 38.987 58.874 54.703 1.00 28.60 ? 854 HOH B O 1 HETATM 12335 O O . HOH T 4 . ? 38.774 76.160 92.623 1.00 39.05 ? 855 HOH B O 1 HETATM 12336 O O . HOH T 4 . ? 64.108 69.792 42.767 1.00 36.91 ? 856 HOH B O 1 HETATM 12337 O O . HOH T 4 . ? 59.797 47.175 66.100 1.00 30.09 ? 857 HOH B O 1 HETATM 12338 O O . HOH T 4 . ? 84.543 83.156 70.332 1.00 36.03 ? 858 HOH B O 1 HETATM 12339 O O . HOH T 4 . ? 78.310 70.592 83.771 1.00 39.41 ? 859 HOH B O 1 HETATM 12340 O O . HOH T 4 . ? 75.802 66.572 104.109 1.00 35.24 ? 860 HOH B O 1 HETATM 12341 O O . HOH T 4 . ? 66.532 57.733 71.093 1.00 32.50 ? 861 HOH B O 1 HETATM 12342 O O . HOH T 4 . ? 69.683 79.544 79.012 1.00 25.48 ? 862 HOH B O 1 HETATM 12343 O O . HOH T 4 . ? 73.511 72.116 77.125 1.00 31.31 ? 863 HOH B O 1 HETATM 12344 O O . HOH T 4 . ? 50.505 74.444 67.654 1.00 33.05 ? 864 HOH B O 1 HETATM 12345 O O . HOH T 4 . ? 56.748 60.841 93.626 1.00 41.75 ? 865 HOH B O 1 HETATM 12346 O O . HOH T 4 . ? 79.917 72.340 69.520 1.00 30.88 ? 866 HOH B O 1 HETATM 12347 O O . HOH T 4 . ? 71.179 72.745 70.768 1.00 34.56 ? 867 HOH B O 1 HETATM 12348 O O . HOH T 4 . ? 75.473 83.997 75.317 1.00 28.61 ? 868 HOH B O 1 HETATM 12349 O O . HOH T 4 . ? 29.553 67.980 93.129 1.00 50.83 ? 869 HOH B O 1 HETATM 12350 O O . HOH T 4 . ? 66.646 48.688 89.554 1.00 40.26 ? 870 HOH B O 1 HETATM 12351 O O . HOH T 4 . ? 57.469 59.519 67.421 1.00 32.40 ? 871 HOH B O 1 HETATM 12352 O O . HOH T 4 . ? 78.018 78.242 78.804 1.00 32.91 ? 872 HOH B O 1 HETATM 12353 O O . HOH T 4 . ? 49.938 56.167 63.207 1.00 30.73 ? 873 HOH B O 1 HETATM 12354 O O . HOH T 4 . ? 58.548 66.003 67.272 1.00 29.78 ? 874 HOH B O 1 HETATM 12355 O O . HOH T 4 . ? 61.546 73.070 75.152 1.00 28.73 ? 875 HOH B O 1 HETATM 12356 O O . HOH T 4 . ? 56.433 53.608 61.712 1.00 29.18 ? 876 HOH B O 1 HETATM 12357 O O . HOH T 4 . ? 67.303 50.311 78.811 1.00 40.12 ? 877 HOH B O 1 HETATM 12358 O O . HOH T 4 . ? 75.258 93.661 78.905 1.00 39.34 ? 878 HOH B O 1 HETATM 12359 O O . HOH T 4 . ? 53.679 79.035 83.244 1.00 39.89 ? 879 HOH B O 1 HETATM 12360 O O . HOH T 4 . ? 38.415 56.388 56.181 1.00 28.71 ? 880 HOH B O 1 HETATM 12361 O O . HOH T 4 . ? 56.395 84.661 56.392 1.00 35.79 ? 881 HOH B O 1 HETATM 12362 O O . HOH T 4 . ? 68.739 48.199 80.506 1.00 38.86 ? 882 HOH B O 1 HETATM 12363 O O . HOH T 4 . ? 80.734 86.459 61.892 1.00 54.85 ? 883 HOH B O 1 HETATM 12364 O O . HOH T 4 . ? 63.007 60.850 104.385 1.00 32.79 ? 884 HOH B O 1 HETATM 12365 O O . HOH T 4 . ? 48.511 48.319 59.789 1.00 35.78 ? 885 HOH B O 1 HETATM 12366 O O . HOH T 4 . ? 49.683 72.357 86.894 1.00 34.25 ? 886 HOH B O 1 HETATM 12367 O O . HOH T 4 . ? 70.137 41.240 71.685 1.00 38.25 ? 887 HOH B O 1 HETATM 12368 O O . HOH T 4 . ? 66.698 67.053 91.402 1.00 38.47 ? 888 HOH B O 1 HETATM 12369 O O . HOH T 4 . ? 41.680 93.057 87.045 1.00 43.65 ? 889 HOH B O 1 HETATM 12370 O O . HOH T 4 . ? 45.479 58.939 80.149 1.00 36.51 ? 890 HOH B O 1 HETATM 12371 O O . HOH T 4 . ? 80.580 58.696 74.069 1.00 31.35 ? 891 HOH B O 1 HETATM 12372 O O . HOH T 4 . ? 72.312 96.864 91.053 1.00 42.32 ? 892 HOH B O 1 HETATM 12373 O O . HOH T 4 . ? 36.734 57.930 52.810 1.00 31.97 ? 893 HOH B O 1 HETATM 12374 O O . HOH T 4 . ? 77.104 57.354 76.333 1.00 33.21 ? 894 HOH B O 1 HETATM 12375 O O . HOH T 4 . ? 55.677 89.298 63.585 1.00 39.14 ? 895 HOH B O 1 HETATM 12376 O O . HOH T 4 . ? 95.160 69.462 84.284 1.00 38.12 ? 896 HOH B O 1 HETATM 12377 O O . HOH T 4 . ? 48.798 72.585 89.601 1.00 36.42 ? 897 HOH B O 1 HETATM 12378 O O . HOH T 4 . ? 42.916 89.643 76.991 1.00 43.33 ? 898 HOH B O 1 HETATM 12379 O O . HOH T 4 . ? 65.657 92.825 66.254 1.00 37.74 ? 899 HOH B O 1 HETATM 12380 O O . HOH T 4 . ? 72.720 41.905 70.984 1.00 34.03 ? 900 HOH B O 1 HETATM 12381 O O . HOH T 4 . ? 76.202 89.997 68.976 1.00 42.32 ? 901 HOH B O 1 HETATM 12382 O O . HOH T 4 . ? 70.483 56.245 105.530 1.00 39.44 ? 902 HOH B O 1 HETATM 12383 O O . HOH T 4 . ? 61.318 82.052 85.148 1.00 47.01 ? 903 HOH B O 1 HETATM 12384 O O . HOH T 4 . ? 42.762 57.987 80.762 1.00 37.78 ? 904 HOH B O 1 HETATM 12385 O O . HOH T 4 . ? 83.766 91.090 85.224 1.00 44.41 ? 905 HOH B O 1 HETATM 12386 O O . HOH T 4 . ? 50.653 67.811 106.355 1.00 38.68 ? 906 HOH B O 1 HETATM 12387 O O . HOH T 4 . ? 44.409 69.930 53.705 1.00 50.25 ? 907 HOH B O 1 HETATM 12388 O O . HOH T 4 . ? 81.643 93.131 90.049 1.00 34.81 ? 908 HOH B O 1 HETATM 12389 O O . HOH T 4 . ? 69.586 92.227 99.275 1.00 39.28 ? 909 HOH B O 1 HETATM 12390 O O . HOH T 4 . ? 68.036 73.227 108.254 1.00 39.94 ? 910 HOH B O 1 HETATM 12391 O O . HOH T 4 . ? 58.898 56.396 106.519 1.00 38.43 ? 911 HOH B O 1 HETATM 12392 O O . HOH T 4 . ? 86.109 79.736 100.209 1.00 47.55 ? 912 HOH B O 1 HETATM 12393 O O . HOH T 4 . ? 43.072 50.546 61.475 1.00 45.89 ? 913 HOH B O 1 HETATM 12394 O O . HOH T 4 . ? 67.074 51.098 54.582 1.00 34.29 ? 914 HOH B O 1 HETATM 12395 O O . HOH T 4 . ? 31.946 83.943 82.931 1.00 40.83 ? 915 HOH B O 1 HETATM 12396 O O . HOH T 4 . ? 57.512 72.426 81.180 1.00 33.69 ? 916 HOH B O 1 HETATM 12397 O O . HOH T 4 . ? 77.605 52.888 79.507 1.00 43.14 ? 917 HOH B O 1 HETATM 12398 O O . HOH T 4 . ? 65.524 63.678 41.968 1.00 39.57 ? 918 HOH B O 1 HETATM 12399 O O . HOH T 4 . ? 87.597 55.080 59.017 1.00 39.89 ? 919 HOH B O 1 HETATM 12400 O O . HOH T 4 . ? 62.393 66.442 75.768 1.00 40.13 ? 920 HOH B O 1 HETATM 12401 O O . HOH T 4 . ? 66.735 76.233 88.114 1.00 53.49 ? 922 HOH B O 1 HETATM 12402 O O . HOH T 4 . ? 57.624 68.748 69.139 1.00 31.26 ? 923 HOH B O 1 HETATM 12403 O O . HOH T 4 . ? 66.131 75.546 74.369 1.00 40.38 ? 924 HOH B O 1 HETATM 12404 O O . HOH T 4 . ? 69.608 80.167 87.353 1.00 18.38 ? 925 HOH B O 1 HETATM 12405 O O . HOH T 4 . ? 62.565 101.279 76.445 1.00 40.96 ? 926 HOH B O 1 HETATM 12406 O O . HOH T 4 . ? 85.259 73.554 84.804 1.00 32.06 ? 927 HOH B O 1 HETATM 12407 O O . HOH T 4 . ? 83.163 66.940 89.531 1.00 42.23 ? 928 HOH B O 1 HETATM 12408 O O . HOH T 4 . ? 49.574 66.353 52.968 1.00 36.27 ? 929 HOH B O 1 HETATM 12409 O O . HOH T 4 . ? 41.704 75.202 70.399 1.00 40.47 ? 930 HOH B O 1 HETATM 12410 O O . HOH T 4 . ? 63.366 84.583 98.341 1.00 43.71 ? 931 HOH B O 1 HETATM 12411 O O . HOH T 4 . ? 53.770 64.251 65.018 1.00 30.07 ? 932 HOH B O 1 HETATM 12412 O O . HOH T 4 . ? 75.597 85.704 105.233 1.00 30.06 ? 933 HOH B O 1 HETATM 12413 O O . HOH T 4 . ? 77.077 54.765 77.410 1.00 32.12 ? 934 HOH B O 1 HETATM 12414 O O . HOH T 4 . ? 59.333 88.371 66.781 1.00 29.97 ? 935 HOH B O 1 HETATM 12415 O O . HOH T 4 . ? 72.347 43.815 66.649 1.00 45.59 ? 936 HOH B O 1 HETATM 12416 O O . HOH T 4 . ? 54.232 55.518 64.056 1.00 35.93 ? 937 HOH B O 1 HETATM 12417 O O . HOH T 4 . ? 68.237 52.812 79.165 1.00 35.94 ? 938 HOH B O 1 HETATM 12418 O O . HOH T 4 . ? 78.123 56.484 48.312 1.00 35.39 ? 939 HOH B O 1 HETATM 12419 O O . HOH T 4 . ? 62.084 88.408 84.580 1.00 36.25 ? 940 HOH B O 1 HETATM 12420 O O . HOH T 4 . ? 56.980 91.174 67.739 1.00 31.57 ? 941 HOH B O 1 HETATM 12421 O O . HOH T 4 . ? 83.276 62.653 52.205 1.00 36.91 ? 942 HOH B O 1 HETATM 12422 O O . HOH T 4 . ? 47.745 74.697 70.903 1.00 36.95 ? 943 HOH B O 1 HETATM 12423 O O . HOH T 4 . ? 65.312 51.714 75.586 1.00 33.64 ? 944 HOH B O 1 HETATM 12424 O O . HOH T 4 . ? 78.555 88.120 57.885 1.00 45.26 ? 945 HOH B O 1 HETATM 12425 O O . HOH T 4 . ? 62.140 54.417 90.455 1.00 37.91 ? 946 HOH B O 1 HETATM 12426 O O . HOH T 4 . ? 43.802 95.200 88.249 1.00 49.40 ? 947 HOH B O 1 HETATM 12427 O O . HOH T 4 . ? 60.910 98.657 84.514 1.00 44.61 ? 948 HOH B O 1 HETATM 12428 O O . HOH T 4 . ? 46.364 66.801 72.228 1.00 36.39 ? 949 HOH B O 1 HETATM 12429 O O . HOH T 4 . ? 51.699 77.072 66.538 1.00 30.35 ? 950 HOH B O 1 HETATM 12430 O O . HOH T 4 . ? 59.452 67.858 112.223 1.00 41.26 ? 951 HOH B O 1 HETATM 12431 O O . HOH T 4 . ? 64.589 43.588 84.552 1.00 51.60 ? 952 HOH B O 1 HETATM 12432 O O . HOH T 4 . ? 81.270 90.303 100.569 1.00 36.89 ? 953 HOH B O 1 HETATM 12433 O O . HOH T 4 . ? 82.314 85.285 108.348 1.00 44.76 ? 954 HOH B O 1 HETATM 12434 O O . HOH T 4 . ? 82.876 87.208 87.796 1.00 33.11 ? 955 HOH B O 1 HETATM 12435 O O . HOH T 4 . ? 82.836 42.129 75.215 1.00 35.50 ? 956 HOH B O 1 HETATM 12436 O O . HOH T 4 . ? 68.992 50.149 53.029 1.00 42.89 ? 957 HOH B O 1 HETATM 12437 O O . HOH T 4 . ? 73.172 76.265 48.502 1.00 48.22 ? 958 HOH B O 1 HETATM 12438 O O . HOH T 4 . ? 83.293 84.410 95.438 1.00 33.46 ? 959 HOH B O 1 HETATM 12439 O O . HOH T 4 . ? 52.035 65.063 68.488 1.00 33.50 ? 960 HOH B O 1 HETATM 12440 O O . HOH T 4 . ? 53.545 61.592 65.677 1.00 33.65 ? 961 HOH B O 1 HETATM 12441 O O . HOH T 4 . ? 32.840 81.788 92.609 1.00 44.09 ? 962 HOH B O 1 HETATM 12442 O O . HOH T 4 . ? 85.512 61.466 53.095 1.00 37.11 ? 963 HOH B O 1 HETATM 12443 O O . HOH T 4 . ? 71.894 64.659 88.928 1.00 36.59 ? 964 HOH B O 1 HETATM 12444 O O . HOH T 4 . ? 54.346 93.053 72.691 1.00 38.07 ? 965 HOH B O 1 HETATM 12445 O O . HOH T 4 . ? 61.896 56.776 101.547 1.00 35.60 ? 966 HOH B O 1 HETATM 12446 O O . HOH T 4 . ? 85.814 73.466 94.400 1.00 36.99 ? 967 HOH B O 1 HETATM 12447 O O . HOH T 4 . ? 77.702 56.376 44.820 1.00 39.79 ? 968 HOH B O 1 HETATM 12448 O O . HOH T 4 . ? 69.297 42.724 92.083 1.00 49.06 ? 969 HOH B O 1 HETATM 12449 O O . HOH T 4 . ? 47.452 57.447 80.123 1.00 47.52 ? 970 HOH B O 1 HETATM 12450 O O . HOH T 4 . ? 53.437 98.477 95.005 1.00 49.59 ? 971 HOH B O 1 HETATM 12451 O O . HOH T 4 . ? 57.382 92.481 61.557 1.00 52.76 ? 972 HOH B O 1 HETATM 12452 O O . HOH T 4 . ? 64.182 80.876 52.392 1.00 40.38 ? 973 HOH B O 1 HETATM 12453 O O . HOH T 4 . ? 74.177 58.718 73.076 1.00 42.48 ? 974 HOH B O 1 HETATM 12454 O O . HOH T 4 . ? 69.374 84.875 73.252 1.00 40.05 ? 975 HOH B O 1 HETATM 12455 O O . HOH T 4 . ? 72.108 79.396 82.332 1.00 43.22 ? 976 HOH B O 1 HETATM 12456 O O . HOH T 4 . ? 39.906 86.187 68.214 1.00 35.01 ? 977 HOH B O 1 HETATM 12457 O O . HOH T 4 . ? 66.942 73.631 92.950 1.00 40.19 ? 978 HOH B O 1 HETATM 12458 O O . HOH T 4 . ? 53.420 69.439 82.418 1.00 45.15 ? 979 HOH B O 1 HETATM 12459 O O . HOH T 4 . ? 64.754 84.532 79.133 1.00 39.04 ? 980 HOH B O 1 HETATM 12460 O O . HOH T 4 . ? 70.294 50.038 55.908 1.00 41.64 ? 981 HOH B O 1 HETATM 12461 O O . HOH T 4 . ? 45.269 44.234 57.147 1.00 41.44 ? 982 HOH B O 1 HETATM 12462 O O . HOH T 4 . ? 63.974 100.180 96.086 1.00 52.23 ? 983 HOH B O 1 HETATM 12463 O O . HOH T 4 . ? 82.599 69.929 67.794 1.00 34.84 ? 984 HOH B O 1 HETATM 12464 O O . HOH T 4 . ? 41.210 61.960 56.064 1.00 36.91 ? 985 HOH B O 1 HETATM 12465 O O . HOH T 4 . ? 63.431 75.533 74.878 1.00 35.11 ? 986 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLU 1 37 ? ? ? A . n A 1 2 PHE 2 38 ? ? ? A . n A 1 3 SER 3 39 ? ? ? A . n A 1 4 ARG 4 40 40 ARG ARG A . n A 1 5 LYS 5 41 41 LYS LYS A . n A 1 6 THR 6 42 42 THR THR A . n A 1 7 TYR 7 43 43 TYR TYR A . n A 1 8 THR 8 44 44 THR THR A . n A 1 9 LEU 9 45 45 LEU LEU A . n A 1 10 THR 10 46 46 THR THR A . n A 1 11 ASP 11 47 47 ASP ASP A . n A 1 12 TYR 12 48 48 TYR TYR A . n A 1 13 LEU 13 49 49 LEU LEU A . n A 1 14 LYS 14 50 50 LYS LYS A . n A 1 15 ASN 15 51 51 ASN ASN A . n A 1 16 THR 16 52 52 THR THR A . n A 1 17 TYR 17 53 53 TYR TYR A . n A 1 18 ARG 18 54 54 ARG ARG A . n A 1 19 LEU 19 55 55 LEU LEU A . n A 1 20 LYS 20 56 56 LYS LYS A . n A 1 21 LEU 21 57 57 LEU LEU A . n A 1 22 TYR 22 58 58 TYR TYR A . n A 1 23 SER 23 59 59 SER SER A . n A 1 24 LEU 24 60 60 LEU LEU A . n A 1 25 ARG 25 61 61 ARG ARG A . n A 1 26 TRP 26 62 62 TRP TRP A . n A 1 27 ILE 27 63 63 ILE ILE A . n A 1 28 SER 28 64 64 SER SER A . n A 1 29 ASP 29 65 65 ASP ASP A . n A 1 30 HIS 30 66 66 HIS HIS A . n A 1 31 GLU 31 67 67 GLU GLU A . n A 1 32 TYR 32 68 68 TYR TYR A . n A 1 33 LEU 33 69 69 LEU LEU A . n A 1 34 TYR 34 70 70 TYR TYR A . n A 1 35 LYS 35 71 71 LYS LYS A . n A 1 36 GLN 36 72 72 GLN GLN A . n A 1 37 GLU 37 73 73 GLU GLU A . n A 1 38 ASN 38 74 74 ASN ASN A . n A 1 39 ASN 39 75 75 ASN ASN A . n A 1 40 ILE 40 76 76 ILE ILE A . n A 1 41 LEU 41 77 77 LEU LEU A . n A 1 42 VAL 42 78 78 VAL VAL A . n A 1 43 PHE 43 79 79 PHE PHE A . n A 1 44 ASN 44 80 80 ASN ASN A . n A 1 45 ALA 45 81 81 ALA ALA A . n A 1 46 GLU 46 82 82 GLU GLU A . n A 1 47 TYR 47 83 83 TYR TYR A . n A 1 48 GLY 48 84 84 GLY GLY A . n A 1 49 ASN 49 85 85 ASN ASN A . n A 1 50 SER 50 86 86 SER SER A . n A 1 51 SER 51 87 87 SER SER A . n A 1 52 VAL 52 88 88 VAL VAL A . n A 1 53 PHE 53 89 89 PHE PHE A . n A 1 54 LEU 54 90 90 LEU LEU A . n A 1 55 GLU 55 91 91 GLU GLU A . n A 1 56 ASN 56 92 92 ASN ASN A . n A 1 57 SER 57 93 93 SER SER A . n A 1 58 THR 58 94 94 THR THR A . n A 1 59 PHE 59 95 95 PHE PHE A . n A 1 60 ASP 60 96 96 ASP ASP A . n A 1 61 GLU 61 97 97 GLU GLU A . n A 1 62 PHE 62 98 98 PHE PHE A . n A 1 63 GLY 63 99 99 GLY GLY A . n A 1 64 HIS 64 100 100 HIS HIS A . n A 1 65 SER 65 101 101 SER SER A . n A 1 66 ILE 66 102 102 ILE ILE A . n A 1 67 ASN 67 103 103 ASN ASN A . n A 1 68 ASP 68 104 104 ASP ASP A . n A 1 69 TYR 69 105 105 TYR TYR A . n A 1 70 SER 70 106 106 SER SER A . n A 1 71 ILE 71 107 107 ILE ILE A . n A 1 72 SER 72 108 108 SER SER A . n A 1 73 PRO 73 109 109 PRO PRO A . n A 1 74 ASP 74 110 110 ASP ASP A . n A 1 75 GLY 75 111 111 GLY GLY A . n A 1 76 GLN 76 112 112 GLN GLN A . n A 1 77 PHE 77 113 113 PHE PHE A . n A 1 78 ILE 78 114 114 ILE ILE A . n A 1 79 LEU 79 115 115 LEU LEU A . n A 1 80 LEU 80 116 116 LEU LEU A . n A 1 81 GLU 81 117 117 GLU GLU A . n A 1 82 TYR 82 118 118 TYR TYR A . n A 1 83 ASN 83 119 119 ASN ASN A . n A 1 84 TYR 84 120 120 TYR TYR A . n A 1 85 VAL 85 121 121 VAL VAL A . n A 1 86 LYS 86 122 122 LYS LYS A . n A 1 87 GLN 87 123 123 GLN GLN A . n A 1 88 TRP 88 124 124 TRP TRP A . n A 1 89 ARG 89 125 125 ARG ARG A . n A 1 90 HIS 90 126 126 HIS HIS A . n A 1 91 SER 91 127 127 SER SER A . n A 1 92 TYR 92 128 128 TYR TYR A . n A 1 93 THR 93 129 129 THR THR A . n A 1 94 ALA 94 130 130 ALA ALA A . n A 1 95 SER 95 131 131 SER SER A . n A 1 96 TYR 96 132 132 TYR TYR A . n A 1 97 ASP 97 133 133 ASP ASP A . n A 1 98 ILE 98 134 134 ILE ILE A . n A 1 99 TYR 99 135 135 TYR TYR A . n A 1 100 ASP 100 136 136 ASP ASP A . n A 1 101 LEU 101 137 137 LEU LEU A . n A 1 102 ASN 102 138 138 ASN ASN A . n A 1 103 LYS 103 139 139 LYS LYS A . n A 1 104 ARG 104 140 140 ARG ARG A . n A 1 105 GLN 105 141 141 GLN GLN A . n A 1 106 LEU 106 142 142 LEU LEU A . n A 1 107 ILE 107 143 143 ILE ILE A . n A 1 108 THR 108 144 144 THR THR A . n A 1 109 GLU 109 145 145 GLU GLU A . n A 1 110 GLU 110 146 146 GLU GLU A . n A 1 111 ARG 111 147 147 ARG ARG A . n A 1 112 ILE 112 148 148 ILE ILE A . n A 1 113 PRO 113 149 149 PRO PRO A . n A 1 114 ASN 114 150 150 ASN ASN A . n A 1 115 ASN 115 151 151 ASN ASN A . n A 1 116 THR 116 152 152 THR THR A . n A 1 117 GLN 117 153 153 GLN GLN A . n A 1 118 TRP 118 154 154 TRP TRP A . n A 1 119 VAL 119 155 155 VAL VAL A . n A 1 120 THR 120 156 156 THR THR A . n A 1 121 TRP 121 157 157 TRP TRP A . n A 1 122 SER 122 158 158 SER SER A . n A 1 123 PRO 123 159 159 PRO PRO A . n A 1 124 VAL 124 160 160 VAL VAL A . n A 1 125 GLY 125 161 161 GLY GLY A . n A 1 126 HIS 126 162 162 HIS HIS A . n A 1 127 LYS 127 163 163 LYS LYS A . n A 1 128 LEU 128 164 164 LEU LEU A . n A 1 129 ALA 129 165 165 ALA ALA A . n A 1 130 TYR 130 166 166 TYR TYR A . n A 1 131 VAL 131 167 167 VAL VAL A . n A 1 132 TRP 132 168 168 TRP TRP A . n A 1 133 ASN 133 169 169 ASN ASN A . n A 1 134 ASN 134 170 170 ASN ASN A . n A 1 135 ASP 135 171 171 ASP ASP A . n A 1 136 ILE 136 172 172 ILE ILE A . n A 1 137 TYR 137 173 173 TYR TYR A . n A 1 138 VAL 138 174 174 VAL VAL A . n A 1 139 LYS 139 175 175 LYS LYS A . n A 1 140 ILE 140 176 176 ILE ILE A . n A 1 141 GLU 141 177 177 GLU GLU A . n A 1 142 PRO 142 178 178 PRO PRO A . n A 1 143 ASN 143 179 179 ASN ASN A . n A 1 144 LEU 144 180 180 LEU LEU A . n A 1 145 PRO 145 181 181 PRO PRO A . n A 1 146 SER 146 182 182 SER SER A . n A 1 147 TYR 147 183 183 TYR TYR A . n A 1 148 ARG 148 184 184 ARG ARG A . n A 1 149 ILE 149 185 185 ILE ILE A . n A 1 150 THR 150 186 186 THR THR A . n A 1 151 TRP 151 187 187 TRP TRP A . n A 1 152 THR 152 188 188 THR THR A . n A 1 153 GLY 153 189 189 GLY GLY A . n A 1 154 LYS 154 190 190 LYS LYS A . n A 1 155 GLU 155 191 191 GLU GLU A . n A 1 156 ASP 156 192 192 ASP ASP A . n A 1 157 ILE 157 193 193 ILE ILE A . n A 1 158 ILE 158 194 194 ILE ILE A . n A 1 159 TYR 159 195 195 TYR TYR A . n A 1 160 ASN 160 196 196 ASN ASN A . n A 1 161 GLY 161 197 197 GLY GLY A . n A 1 162 ILE 162 198 198 ILE ILE A . n A 1 163 THR 163 199 199 THR THR A . n A 1 164 ASP 164 200 200 ASP ASP A . n A 1 165 TRP 165 201 201 TRP TRP A . n A 1 166 VAL 166 202 202 VAL VAL A . n A 1 167 TYR 167 203 203 TYR TYR A . n A 1 168 GLU 168 204 204 GLU GLU A . n A 1 169 GLU 169 205 205 GLU GLU A . n A 1 170 GLU 170 206 206 GLU GLU A . n A 1 171 VAL 171 207 207 VAL VAL A . n A 1 172 PHE 172 208 208 PHE PHE A . n A 1 173 SER 173 209 209 SER SER A . n A 1 174 ALA 174 210 210 ALA ALA A . n A 1 175 TYR 175 211 211 TYR TYR A . n A 1 176 SER 176 212 212 SER SER A . n A 1 177 ALA 177 213 213 ALA ALA A . n A 1 178 LEU 178 214 214 LEU LEU A . n A 1 179 TRP 179 215 215 TRP TRP A . n A 1 180 TRP 180 216 216 TRP TRP A . n A 1 181 SER 181 217 217 SER SER A . n A 1 182 PRO 182 218 218 PRO PRO A . n A 1 183 ASN 183 219 219 ASN ASN A . n A 1 184 GLY 184 220 220 GLY GLY A . n A 1 185 THR 185 221 221 THR THR A . n A 1 186 PHE 186 222 222 PHE PHE A . n A 1 187 LEU 187 223 223 LEU LEU A . n A 1 188 ALA 188 224 224 ALA ALA A . n A 1 189 TYR 189 225 225 TYR TYR A . n A 1 190 ALA 190 226 226 ALA ALA A . n A 1 191 GLN 191 227 227 GLN GLN A . n A 1 192 PHE 192 228 228 PHE PHE A . n A 1 193 ASN 193 229 229 ASN ASN A . n A 1 194 ASP 194 230 230 ASP ASP A . n A 1 195 THR 195 231 231 THR THR A . n A 1 196 GLU 196 232 232 GLU GLU A . n A 1 197 VAL 197 233 233 VAL VAL A . n A 1 198 PRO 198 234 234 PRO PRO A . n A 1 199 LEU 199 235 235 LEU LEU A . n A 1 200 ILE 200 236 236 ILE ILE A . n A 1 201 GLU 201 237 237 GLU GLU A . n A 1 202 TYR 202 238 238 TYR TYR A . n A 1 203 SER 203 239 239 SER SER A . n A 1 204 PHE 204 240 240 PHE PHE A . n A 1 205 TYR 205 241 241 TYR TYR A . n A 1 206 SER 206 242 242 SER SER A . n A 1 207 ASP 207 243 243 ASP ASP A . n A 1 208 GLU 208 244 244 GLU GLU A . n A 1 209 SER 209 245 245 SER SER A . n A 1 210 LEU 210 246 246 LEU LEU A . n A 1 211 GLN 211 247 247 GLN GLN A . n A 1 212 TYR 212 248 248 TYR TYR A . n A 1 213 PRO 213 249 249 PRO PRO A . n A 1 214 LYS 214 250 250 LYS LYS A . n A 1 215 THR 215 251 251 THR THR A . n A 1 216 VAL 216 252 252 VAL VAL A . n A 1 217 ARG 217 253 253 ARG ARG A . n A 1 218 VAL 218 254 254 VAL VAL A . n A 1 219 PRO 219 255 255 PRO PRO A . n A 1 220 TYR 220 256 256 TYR TYR A . n A 1 221 PRO 221 257 257 PRO PRO A . n A 1 222 LYS 222 258 258 LYS LYS A . n A 1 223 ALA 223 259 259 ALA ALA A . n A 1 224 GLY 224 260 260 GLY GLY A . n A 1 225 ALA 225 261 261 ALA ALA A . n A 1 226 VAL 226 262 262 VAL VAL A . n A 1 227 ASN 227 263 263 ASN ASN A . n A 1 228 PRO 228 264 264 PRO PRO A . n A 1 229 THR 229 265 265 THR THR A . n A 1 230 VAL 230 266 266 VAL VAL A . n A 1 231 LYS 231 267 267 LYS LYS A . n A 1 232 PHE 232 268 268 PHE PHE A . n A 1 233 PHE 233 269 269 PHE PHE A . n A 1 234 VAL 234 270 270 VAL VAL A . n A 1 235 VAL 235 271 271 VAL VAL A . n A 1 236 ASN 236 272 272 ASN ASN A . n A 1 237 THR 237 273 273 THR THR A . n A 1 238 ASP 238 274 274 ASP ASP A . n A 1 239 SER 239 275 275 SER SER A . n A 1 240 LEU 240 276 276 LEU LEU A . n A 1 241 SER 241 277 277 SER SER A . n A 1 242 SER 242 278 278 SER SER A . n A 1 243 VAL 243 279 279 VAL VAL A . n A 1 244 THR 244 280 280 THR THR A . n A 1 245 ASN 245 281 281 ASN ASN A . n A 1 246 ALA 246 282 282 ALA ALA A . n A 1 247 THR 247 283 283 THR THR A . n A 1 248 SER 248 284 284 SER SER A . n A 1 249 ILE 249 285 285 ILE ILE A . n A 1 250 GLN 250 286 286 GLN GLN A . n A 1 251 ILE 251 287 287 ILE ILE A . n A 1 252 THR 252 288 288 THR THR A . n A 1 253 ALA 253 289 289 ALA ALA A . n A 1 254 PRO 254 290 290 PRO PRO A . n A 1 255 ALA 255 291 291 ALA ALA A . n A 1 256 SER 256 292 292 SER SER A . n A 1 257 MET 257 293 293 MET MET A . n A 1 258 LEU 258 294 294 LEU LEU A . n A 1 259 ILE 259 295 295 ILE ILE A . n A 1 260 GLY 260 296 296 GLY GLY A . n A 1 261 ASP 261 297 297 ASP ASP A . n A 1 262 HIS 262 298 298 HIS HIS A . n A 1 263 TYR 263 299 299 TYR TYR A . n A 1 264 LEU 264 300 300 LEU LEU A . n A 1 265 CYS 265 301 301 CYS CYS A . n A 1 266 ASP 266 302 302 ASP ASP A . n A 1 267 VAL 267 303 303 VAL VAL A . n A 1 268 THR 268 304 304 THR THR A . n A 1 269 TRP 269 305 305 TRP TRP A . n A 1 270 ALA 270 306 306 ALA ALA A . n A 1 271 THR 271 307 307 THR THR A . n A 1 272 GLN 272 308 308 GLN GLN A . n A 1 273 GLU 273 309 309 GLU GLU A . n A 1 274 ARG 274 310 310 ARG ARG A . n A 1 275 ILE 275 311 311 ILE ILE A . n A 1 276 SER 276 312 312 SER SER A . n A 1 277 LEU 277 313 313 LEU LEU A . n A 1 278 GLN 278 314 314 GLN GLN A . n A 1 279 TRP 279 315 315 TRP TRP A . n A 1 280 LEU 280 316 316 LEU LEU A . n A 1 281 ARG 281 317 317 ARG ARG A . n A 1 282 ARG 282 318 318 ARG ARG A . n A 1 283 ILE 283 319 319 ILE ILE A . n A 1 284 GLN 284 320 320 GLN GLN A . n A 1 285 ASN 285 321 321 ASN ASN A . n A 1 286 TYR 286 322 322 TYR TYR A . n A 1 287 SER 287 323 323 SER SER A . n A 1 288 VAL 288 324 324 VAL VAL A . n A 1 289 MET 289 325 325 MET MET A . n A 1 290 ASP 290 326 326 ASP ASP A . n A 1 291 ILE 291 327 327 ILE ILE A . n A 1 292 CYS 292 328 328 CYS CYS A . n A 1 293 ASP 293 329 329 ASP ASP A . n A 1 294 TYR 294 330 330 TYR TYR A . n A 1 295 ASP 295 331 331 ASP ASP A . n A 1 296 GLU 296 332 332 GLU GLU A . n A 1 297 SER 297 333 333 SER SER A . n A 1 298 SER 298 334 334 SER SER A . n A 1 299 GLY 299 335 335 GLY GLY A . n A 1 300 ARG 300 336 336 ARG ARG A . n A 1 301 TRP 301 337 337 TRP TRP A . n A 1 302 ASN 302 338 338 ASN ASN A . n A 1 303 CYS 303 339 339 CYS CYS A . n A 1 304 LEU 304 340 340 LEU LEU A . n A 1 305 VAL 305 341 341 VAL VAL A . n A 1 306 ALA 306 342 342 ALA ALA A . n A 1 307 ARG 307 343 343 ARG ARG A . n A 1 308 GLN 308 344 344 GLN GLN A . n A 1 309 HIS 309 345 345 HIS HIS A . n A 1 310 ILE 310 346 346 ILE ILE A . n A 1 311 GLU 311 347 347 GLU GLU A . n A 1 312 MET 312 348 348 MET MET A . n A 1 313 SER 313 349 349 SER SER A . n A 1 314 THR 314 350 350 THR THR A . n A 1 315 THR 315 351 351 THR THR A . n A 1 316 GLY 316 352 352 GLY GLY A . n A 1 317 TRP 317 353 353 TRP TRP A . n A 1 318 VAL 318 354 354 VAL VAL A . n A 1 319 GLY 319 355 355 GLY GLY A . n A 1 320 ARG 320 356 356 ARG ARG A . n A 1 321 PHE 321 357 357 PHE PHE A . n A 1 322 ARG 322 358 358 ARG ARG A . n A 1 323 PRO 323 359 359 PRO PRO A . n A 1 324 SER 324 360 360 SER SER A . n A 1 325 GLU 325 361 361 GLU GLU A . n A 1 326 PRO 326 362 362 PRO PRO A . n A 1 327 HIS 327 363 363 HIS HIS A . n A 1 328 PHE 328 364 364 PHE PHE A . n A 1 329 THR 329 365 365 THR THR A . n A 1 330 LEU 330 366 366 LEU LEU A . n A 1 331 ASP 331 367 367 ASP ASP A . n A 1 332 GLY 332 368 368 GLY GLY A . n A 1 333 ASN 333 369 369 ASN ASN A . n A 1 334 SER 334 370 370 SER SER A . n A 1 335 PHE 335 371 371 PHE PHE A . n A 1 336 TYR 336 372 372 TYR TYR A . n A 1 337 LYS 337 373 373 LYS LYS A . n A 1 338 ILE 338 374 374 ILE ILE A . n A 1 339 ILE 339 375 375 ILE ILE A . n A 1 340 SER 340 376 376 SER SER A . n A 1 341 ASN 341 377 377 ASN ASN A . n A 1 342 GLU 342 378 378 GLU GLU A . n A 1 343 GLU 343 379 379 GLU GLU A . n A 1 344 GLY 344 380 380 GLY GLY A . n A 1 345 TYR 345 381 381 TYR TYR A . n A 1 346 ARG 346 382 382 ARG ARG A . n A 1 347 HIS 347 383 383 HIS HIS A . n A 1 348 ILE 348 384 384 ILE ILE A . n A 1 349 CYS 349 385 385 CYS CYS A . n A 1 350 TYR 350 386 386 TYR TYR A . n A 1 351 PHE 351 387 387 PHE PHE A . n A 1 352 GLN 352 388 388 GLN GLN A . n A 1 353 ILE 353 389 389 ILE ILE A . n A 1 354 ASP 354 390 390 ASP ASP A . n A 1 355 LYS 355 391 391 LYS LYS A . n A 1 356 LYS 356 392 392 LYS LYS A . n A 1 357 ASP 357 393 393 ASP ASP A . n A 1 358 CYS 358 394 394 CYS CYS A . n A 1 359 THR 359 395 395 THR THR A . n A 1 360 PHE 360 396 396 PHE PHE A . n A 1 361 ILE 361 397 397 ILE ILE A . n A 1 362 THR 362 398 398 THR THR A . n A 1 363 LYS 363 399 399 LYS LYS A . n A 1 364 GLY 364 400 400 GLY GLY A . n A 1 365 THR 365 401 401 THR THR A . n A 1 366 TRP 366 402 402 TRP TRP A . n A 1 367 GLU 367 403 403 GLU GLU A . n A 1 368 VAL 368 404 404 VAL VAL A . n A 1 369 ILE 369 405 405 ILE ILE A . n A 1 370 GLY 370 406 406 GLY GLY A . n A 1 371 ILE 371 407 407 ILE ILE A . n A 1 372 GLU 372 408 408 GLU GLU A . n A 1 373 ALA 373 409 409 ALA ALA A . n A 1 374 LEU 374 410 410 LEU LEU A . n A 1 375 THR 375 411 411 THR THR A . n A 1 376 SER 376 412 412 SER SER A . n A 1 377 ASP 377 413 413 ASP ASP A . n A 1 378 TYR 378 414 414 TYR TYR A . n A 1 379 LEU 379 415 415 LEU LEU A . n A 1 380 TYR 380 416 416 TYR TYR A . n A 1 381 TYR 381 417 417 TYR TYR A . n A 1 382 ILE 382 418 418 ILE ILE A . n A 1 383 SER 383 419 419 SER SER A . n A 1 384 ASN 384 420 420 ASN ASN A . n A 1 385 GLU 385 421 421 GLU GLU A . n A 1 386 TYR 386 422 422 TYR TYR A . n A 1 387 LYS 387 423 423 LYS LYS A . n A 1 388 GLY 388 424 424 GLY GLY A . n A 1 389 MET 389 425 425 MET MET A . n A 1 390 PRO 390 426 426 PRO PRO A . n A 1 391 GLY 391 427 427 GLY GLY A . n A 1 392 GLY 392 428 428 GLY GLY A . n A 1 393 ARG 393 429 429 ARG ARG A . n A 1 394 ASN 394 430 430 ASN ASN A . n A 1 395 LEU 395 431 431 LEU LEU A . n A 1 396 TYR 396 432 432 TYR TYR A . n A 1 397 LYS 397 433 433 LYS LYS A . n A 1 398 ILE 398 434 434 ILE ILE A . n A 1 399 GLN 399 435 435 GLN GLN A . n A 1 400 LEU 400 436 436 LEU LEU A . n A 1 401 SER 401 437 437 SER SER A . n A 1 402 ASP 402 438 438 ASP ASP A . n A 1 403 TYR 403 439 439 TYR TYR A . n A 1 404 THR 404 440 440 THR THR A . n A 1 405 LYS 405 441 441 LYS LYS A . n A 1 406 VAL 406 442 442 VAL VAL A . n A 1 407 THR 407 443 443 THR THR A . n A 1 408 CYS 408 444 444 CYS CYS A . n A 1 409 LEU 409 445 445 LEU LEU A . n A 1 410 SER 410 446 446 SER SER A . n A 1 411 CYS 411 447 447 CYS CYS A . n A 1 412 GLU 412 448 448 GLU GLU A . n A 1 413 LEU 413 449 449 LEU LEU A . n A 1 414 ASN 414 450 450 ASN ASN A . n A 1 415 PRO 415 451 451 PRO PRO A . n A 1 416 GLU 416 452 452 GLU GLU A . n A 1 417 ARG 417 453 453 ARG ARG A . n A 1 418 CYS 418 454 454 CYS CYS A . n A 1 419 GLN 419 455 455 GLN GLN A . n A 1 420 TYR 420 456 456 TYR TYR A . n A 1 421 TYR 421 457 457 TYR TYR A . n A 1 422 SER 422 458 458 SER SER A . n A 1 423 VAL 423 459 459 VAL VAL A . n A 1 424 SER 424 460 460 SER SER A . n A 1 425 PHE 425 461 461 PHE PHE A . n A 1 426 SER 426 462 462 SER SER A . n A 1 427 LYS 427 463 463 LYS LYS A . n A 1 428 GLU 428 464 464 GLU GLU A . n A 1 429 ALA 429 465 465 ALA ALA A . n A 1 430 LYS 430 466 466 LYS LYS A . n A 1 431 TYR 431 467 467 TYR TYR A . n A 1 432 TYR 432 468 468 TYR TYR A . n A 1 433 GLN 433 469 469 GLN GLN A . n A 1 434 LEU 434 470 470 LEU LEU A . n A 1 435 ARG 435 471 471 ARG ARG A . n A 1 436 CYS 436 472 472 CYS CYS A . n A 1 437 SER 437 473 473 SER SER A . n A 1 438 GLY 438 474 474 GLY GLY A . n A 1 439 PRO 439 475 475 PRO PRO A . n A 1 440 GLY 440 476 476 GLY GLY A . n A 1 441 LEU 441 477 477 LEU LEU A . n A 1 442 PRO 442 478 478 PRO PRO A . n A 1 443 LEU 443 479 479 LEU LEU A . n A 1 444 TYR 444 480 480 TYR TYR A . n A 1 445 THR 445 481 481 THR THR A . n A 1 446 LEU 446 482 482 LEU LEU A . n A 1 447 HIS 447 483 483 HIS HIS A . n A 1 448 SER 448 484 484 SER SER A . n A 1 449 SER 449 485 485 SER SER A . n A 1 450 VAL 450 486 486 VAL VAL A . n A 1 451 ASN 451 487 487 ASN ASN A . n A 1 452 ASP 452 488 488 ASP ASP A . n A 1 453 LYS 453 489 489 LYS LYS A . n A 1 454 GLY 454 490 490 GLY GLY A . n A 1 455 LEU 455 491 491 LEU LEU A . n A 1 456 ARG 456 492 492 ARG ARG A . n A 1 457 VAL 457 493 493 VAL VAL A . n A 1 458 LEU 458 494 494 LEU LEU A . n A 1 459 GLU 459 495 495 GLU GLU A . n A 1 460 ASP 460 496 496 ASP ASP A . n A 1 461 ASN 461 497 497 ASN ASN A . n A 1 462 SER 462 498 498 SER SER A . n A 1 463 ALA 463 499 499 ALA ALA A . n A 1 464 LEU 464 500 500 LEU LEU A . n A 1 465 ASP 465 501 501 ASP ASP A . n A 1 466 LYS 466 502 502 LYS LYS A . n A 1 467 MET 467 503 503 MET MET A . n A 1 468 LEU 468 504 504 LEU LEU A . n A 1 469 GLN 469 505 505 GLN GLN A . n A 1 470 ASN 470 506 506 ASN ASN A . n A 1 471 VAL 471 507 507 VAL VAL A . n A 1 472 GLN 472 508 508 GLN GLN A . n A 1 473 MET 473 509 509 MET MET A . n A 1 474 PRO 474 510 510 PRO PRO A . n A 1 475 SER 475 511 511 SER SER A . n A 1 476 LYS 476 512 512 LYS LYS A . n A 1 477 LYS 477 513 513 LYS LYS A . n A 1 478 LEU 478 514 514 LEU LEU A . n A 1 479 ASP 479 515 515 ASP ASP A . n A 1 480 PHE 480 516 516 PHE PHE A . n A 1 481 ILE 481 517 517 ILE ILE A . n A 1 482 ILE 482 518 518 ILE ILE A . n A 1 483 LEU 483 519 519 LEU LEU A . n A 1 484 ASN 484 520 520 ASN ASN A . n A 1 485 GLU 485 521 521 GLU GLU A . n A 1 486 THR 486 522 522 THR THR A . n A 1 487 LYS 487 523 523 LYS LYS A . n A 1 488 PHE 488 524 524 PHE PHE A . n A 1 489 TRP 489 525 525 TRP TRP A . n A 1 490 TYR 490 526 526 TYR TYR A . n A 1 491 GLN 491 527 527 GLN GLN A . n A 1 492 MET 492 528 528 MET MET A . n A 1 493 ILE 493 529 529 ILE ILE A . n A 1 494 LEU 494 530 530 LEU LEU A . n A 1 495 PRO 495 531 531 PRO PRO A . n A 1 496 PRO 496 532 532 PRO PRO A . n A 1 497 HIS 497 533 533 HIS HIS A . n A 1 498 PHE 498 534 534 PHE PHE A . n A 1 499 ASP 499 535 535 ASP ASP A . n A 1 500 LYS 500 536 536 LYS LYS A . n A 1 501 SER 501 537 537 SER SER A . n A 1 502 LYS 502 538 538 LYS LYS A . n A 1 503 LYS 503 539 539 LYS LYS A . n A 1 504 TYR 504 540 540 TYR TYR A . n A 1 505 PRO 505 541 541 PRO PRO A . n A 1 506 LEU 506 542 542 LEU LEU A . n A 1 507 LEU 507 543 543 LEU LEU A . n A 1 508 LEU 508 544 544 LEU LEU A . n A 1 509 ASP 509 545 545 ASP ASP A . n A 1 510 VAL 510 546 546 VAL VAL A . n A 1 511 TYR 511 547 547 TYR TYR A . n A 1 512 ALA 512 548 548 ALA ALA A . n A 1 513 GLY 513 549 549 GLY GLY A . n A 1 514 PRO 514 550 550 PRO PRO A . n A 1 515 CYS 515 551 551 CYS CYS A . n A 1 516 SER 516 552 552 SER SER A . n A 1 517 GLN 517 553 553 GLN GLN A . n A 1 518 LYS 518 554 554 LYS LYS A . n A 1 519 ALA 519 555 555 ALA ALA A . n A 1 520 ASP 520 556 556 ASP ASP A . n A 1 521 THR 521 557 557 THR THR A . n A 1 522 VAL 522 558 558 VAL VAL A . n A 1 523 PHE 523 559 559 PHE PHE A . n A 1 524 ARG 524 560 560 ARG ARG A . n A 1 525 LEU 525 561 561 LEU LEU A . n A 1 526 ASN 526 562 562 ASN ASN A . n A 1 527 TRP 527 563 563 TRP TRP A . n A 1 528 ALA 528 564 564 ALA ALA A . n A 1 529 THR 529 565 565 THR THR A . n A 1 530 TYR 530 566 566 TYR TYR A . n A 1 531 LEU 531 567 567 LEU LEU A . n A 1 532 ALA 532 568 568 ALA ALA A . n A 1 533 SER 533 569 569 SER SER A . n A 1 534 THR 534 570 570 THR THR A . n A 1 535 GLU 535 571 571 GLU GLU A . n A 1 536 ASN 536 572 572 ASN ASN A . n A 1 537 ILE 537 573 573 ILE ILE A . n A 1 538 ILE 538 574 574 ILE ILE A . n A 1 539 VAL 539 575 575 VAL VAL A . n A 1 540 ALA 540 576 576 ALA ALA A . n A 1 541 SER 541 577 577 SER SER A . n A 1 542 PHE 542 578 578 PHE PHE A . n A 1 543 ASP 543 579 579 ASP ASP A . n A 1 544 GLY 544 580 580 GLY GLY A . n A 1 545 ARG 545 581 581 ARG ARG A . n A 1 546 GLY 546 582 582 GLY GLY A . n A 1 547 SER 547 583 583 SER SER A . n A 1 548 GLY 548 584 584 GLY GLY A . n A 1 549 TYR 549 585 585 TYR TYR A . n A 1 550 GLN 550 586 586 GLN GLN A . n A 1 551 GLY 551 587 587 GLY GLY A . n A 1 552 ASP 552 588 588 ASP ASP A . n A 1 553 LYS 553 589 589 LYS LYS A . n A 1 554 ILE 554 590 590 ILE ILE A . n A 1 555 MET 555 591 591 MET MET A . n A 1 556 HIS 556 592 592 HIS HIS A . n A 1 557 ALA 557 593 593 ALA ALA A . n A 1 558 ILE 558 594 594 ILE ILE A . n A 1 559 ASN 559 595 595 ASN ASN A . n A 1 560 ARG 560 596 596 ARG ARG A . n A 1 561 ARG 561 597 597 ARG ARG A . n A 1 562 LEU 562 598 598 LEU LEU A . n A 1 563 GLY 563 599 599 GLY GLY A . n A 1 564 THR 564 600 600 THR THR A . n A 1 565 PHE 565 601 601 PHE PHE A . n A 1 566 GLU 566 602 602 GLU GLU A . n A 1 567 VAL 567 603 603 VAL VAL A . n A 1 568 GLU 568 604 604 GLU GLU A . n A 1 569 ASP 569 605 605 ASP ASP A . n A 1 570 GLN 570 606 606 GLN GLN A . n A 1 571 ILE 571 607 607 ILE ILE A . n A 1 572 GLU 572 608 608 GLU GLU A . n A 1 573 ALA 573 609 609 ALA ALA A . n A 1 574 ALA 574 610 610 ALA ALA A . n A 1 575 ARG 575 611 611 ARG ARG A . n A 1 576 GLN 576 612 612 GLN GLN A . n A 1 577 PHE 577 613 613 PHE PHE A . n A 1 578 SER 578 614 614 SER SER A . n A 1 579 LYS 579 615 615 LYS LYS A . n A 1 580 MET 580 616 616 MET MET A . n A 1 581 GLY 581 617 617 GLY GLY A . n A 1 582 PHE 582 618 618 PHE PHE A . n A 1 583 VAL 583 619 619 VAL VAL A . n A 1 584 ASP 584 620 620 ASP ASP A . n A 1 585 ASN 585 621 621 ASN ASN A . n A 1 586 LYS 586 622 622 LYS LYS A . n A 1 587 ARG 587 623 623 ARG ARG A . n A 1 588 ILE 588 624 624 ILE ILE A . n A 1 589 ALA 589 625 625 ALA ALA A . n A 1 590 ILE 590 626 626 ILE ILE A . n A 1 591 TRP 591 627 627 TRP TRP A . n A 1 592 GLY 592 628 628 GLY GLY A . n A 1 593 TRP 593 629 629 TRP TRP A . n A 1 594 SER 594 630 630 SER SER A . n A 1 595 TYR 595 631 631 TYR TYR A . n A 1 596 GLY 596 632 632 GLY GLY A . n A 1 597 GLY 597 633 633 GLY GLY A . n A 1 598 TYR 598 634 634 TYR TYR A . n A 1 599 VAL 599 635 635 VAL VAL A . n A 1 600 THR 600 636 636 THR THR A . n A 1 601 SER 601 637 637 SER SER A . n A 1 602 MET 602 638 638 MET MET A . n A 1 603 VAL 603 639 639 VAL VAL A . n A 1 604 LEU 604 640 640 LEU LEU A . n A 1 605 GLY 605 641 641 GLY GLY A . n A 1 606 SER 606 642 642 SER SER A . n A 1 607 GLY 607 643 643 GLY GLY A . n A 1 608 SER 608 644 644 SER SER A . n A 1 609 GLY 609 645 645 GLY GLY A . n A 1 610 VAL 610 646 646 VAL VAL A . n A 1 611 PHE 611 647 647 PHE PHE A . n A 1 612 LYS 612 648 648 LYS LYS A . n A 1 613 CYS 613 649 649 CYS CYS A . n A 1 614 GLY 614 650 650 GLY GLY A . n A 1 615 ILE 615 651 651 ILE ILE A . n A 1 616 ALA 616 652 652 ALA ALA A . n A 1 617 VAL 617 653 653 VAL VAL A . n A 1 618 ALA 618 654 654 ALA ALA A . n A 1 619 PRO 619 655 655 PRO PRO A . n A 1 620 VAL 620 656 656 VAL VAL A . n A 1 621 SER 621 657 657 SER SER A . n A 1 622 ARG 622 658 658 ARG ARG A . n A 1 623 TRP 623 659 659 TRP TRP A . n A 1 624 GLU 624 660 660 GLU GLU A . n A 1 625 TYR 625 661 661 TYR TYR A . n A 1 626 TYR 626 662 662 TYR TYR A . n A 1 627 ASP 627 663 663 ASP ASP A . n A 1 628 SER 628 664 664 SER SER A . n A 1 629 VAL 629 665 665 VAL VAL A . n A 1 630 TYR 630 666 666 TYR TYR A . n A 1 631 THR 631 667 667 THR THR A . n A 1 632 GLU 632 668 668 GLU GLU A . n A 1 633 ARG 633 669 669 ARG ARG A . n A 1 634 TYR 634 670 670 TYR TYR A . n A 1 635 MET 635 671 671 MET MET A . n A 1 636 GLY 636 672 672 GLY GLY A . n A 1 637 LEU 637 673 673 LEU LEU A . n A 1 638 PRO 638 674 674 PRO PRO A . n A 1 639 THR 639 675 675 THR THR A . n A 1 640 PRO 640 676 676 PRO PRO A . n A 1 641 GLU 641 677 677 GLU GLU A . n A 1 642 ASP 642 678 678 ASP ASP A . n A 1 643 ASN 643 679 679 ASN ASN A . n A 1 644 LEU 644 680 680 LEU LEU A . n A 1 645 ASP 645 681 681 ASP ASP A . n A 1 646 HIS 646 682 682 HIS HIS A . n A 1 647 TYR 647 683 683 TYR TYR A . n A 1 648 ARG 648 684 684 ARG ARG A . n A 1 649 ASN 649 685 685 ASN ASN A . n A 1 650 SER 650 686 686 SER SER A . n A 1 651 THR 651 687 687 THR THR A . n A 1 652 VAL 652 688 688 VAL VAL A . n A 1 653 MET 653 689 689 MET MET A . n A 1 654 SER 654 690 690 SER SER A . n A 1 655 ARG 655 691 691 ARG ARG A . n A 1 656 ALA 656 692 692 ALA ALA A . n A 1 657 GLU 657 693 693 GLU GLU A . n A 1 658 ASN 658 694 694 ASN ASN A . n A 1 659 PHE 659 695 695 PHE PHE A . n A 1 660 LYS 660 696 696 LYS LYS A . n A 1 661 GLN 661 697 697 GLN GLN A . n A 1 662 VAL 662 698 698 VAL VAL A . n A 1 663 GLU 663 699 699 GLU GLU A . n A 1 664 TYR 664 700 700 TYR TYR A . n A 1 665 LEU 665 701 701 LEU LEU A . n A 1 666 LEU 666 702 702 LEU LEU A . n A 1 667 ILE 667 703 703 ILE ILE A . n A 1 668 HIS 668 704 704 HIS HIS A . n A 1 669 GLY 669 705 705 GLY GLY A . n A 1 670 THR 670 706 706 THR THR A . n A 1 671 ALA 671 707 707 ALA ALA A . n A 1 672 ASP 672 708 708 ASP ASP A . n A 1 673 ASP 673 709 709 ASP ASP A . n A 1 674 ASN 674 710 710 ASN ASN A . n A 1 675 VAL 675 711 711 VAL VAL A . n A 1 676 HIS 676 712 712 HIS HIS A . n A 1 677 PHE 677 713 713 PHE PHE A . n A 1 678 GLN 678 714 714 GLN GLN A . n A 1 679 GLN 679 715 715 GLN GLN A . n A 1 680 SER 680 716 716 SER SER A . n A 1 681 ALA 681 717 717 ALA ALA A . n A 1 682 GLN 682 718 718 GLN GLN A . n A 1 683 ILE 683 719 719 ILE ILE A . n A 1 684 SER 684 720 720 SER SER A . n A 1 685 LYS 685 721 721 LYS LYS A . n A 1 686 ALA 686 722 722 ALA ALA A . n A 1 687 LEU 687 723 723 LEU LEU A . n A 1 688 VAL 688 724 724 VAL VAL A . n A 1 689 ASP 689 725 725 ASP ASP A . n A 1 690 VAL 690 726 726 VAL VAL A . n A 1 691 GLY 691 727 727 GLY GLY A . n A 1 692 VAL 692 728 728 VAL VAL A . n A 1 693 ASP 693 729 729 ASP ASP A . n A 1 694 PHE 694 730 730 PHE PHE A . n A 1 695 GLN 695 731 731 GLN GLN A . n A 1 696 ALA 696 732 732 ALA ALA A . n A 1 697 MET 697 733 733 MET MET A . n A 1 698 TRP 698 734 734 TRP TRP A . n A 1 699 TYR 699 735 735 TYR TYR A . n A 1 700 THR 700 736 736 THR THR A . n A 1 701 ASP 701 737 737 ASP ASP A . n A 1 702 GLU 702 738 738 GLU GLU A . n A 1 703 ASP 703 739 739 ASP ASP A . n A 1 704 HIS 704 740 740 HIS HIS A . n A 1 705 GLY 705 741 741 GLY GLY A . n A 1 706 ILE 706 742 742 ILE ILE A . n A 1 707 ALA 707 743 743 ALA ALA A . n A 1 708 SER 708 744 744 SER SER A . n A 1 709 SER 709 745 745 SER SER A . n A 1 710 THR 710 746 746 THR THR A . n A 1 711 ALA 711 747 747 ALA ALA A . n A 1 712 HIS 712 748 748 HIS HIS A . n A 1 713 GLN 713 749 749 GLN GLN A . n A 1 714 HIS 714 750 750 HIS HIS A . n A 1 715 ILE 715 751 751 ILE ILE A . n A 1 716 TYR 716 752 752 TYR TYR A . n A 1 717 THR 717 753 753 THR THR A . n A 1 718 HIS 718 754 754 HIS HIS A . n A 1 719 MET 719 755 755 MET MET A . n A 1 720 SER 720 756 756 SER SER A . n A 1 721 HIS 721 757 757 HIS HIS A . n A 1 722 PHE 722 758 758 PHE PHE A . n A 1 723 ILE 723 759 759 ILE ILE A . n A 1 724 LYS 724 760 760 LYS LYS A . n A 1 725 GLN 725 761 761 GLN GLN A . n A 1 726 CYS 726 762 762 CYS CYS A . n A 1 727 PHE 727 763 763 PHE PHE A . n A 1 728 SER 728 764 764 SER SER A . n A 1 729 LEU 729 765 765 LEU LEU A . n A 1 730 PRO 730 766 766 PRO PRO A . n A 1 731 PRO 731 767 ? ? ? A . n A 1 732 LEU 732 768 ? ? ? A . n A 1 733 GLU 733 769 ? ? ? A . n A 1 734 GLN 734 770 ? ? ? A . n A 1 735 LYS 735 771 ? ? ? A . n A 1 736 LEU 736 772 ? ? ? A . n A 1 737 ILE 737 773 ? ? ? A . n A 1 738 SER 738 774 ? ? ? A . n A 1 739 GLU 739 775 ? ? ? A . n A 1 740 GLU 740 776 ? ? ? A . n A 1 741 ASP 741 777 ? ? ? A . n A 1 742 LEU 742 778 ? ? ? A . n A 1 743 ASN 743 779 ? ? ? A . n A 1 744 SER 744 780 ? ? ? A . n A 1 745 ALA 745 781 ? ? ? A . n A 1 746 VAL 746 782 ? ? ? A . n A 1 747 ASP 747 783 ? ? ? A . n A 1 748 HIS 748 784 ? ? ? A . n A 1 749 HIS 749 785 ? ? ? A . n A 1 750 HIS 750 786 ? ? ? A . n A 1 751 HIS 751 787 ? ? ? A . n A 1 752 HIS 752 788 ? ? ? A . n A 1 753 HIS 753 789 ? ? ? A . n B 1 1 GLU 1 37 ? ? ? B . n B 1 2 PHE 2 38 ? ? ? B . n B 1 3 SER 3 39 ? ? ? B . n B 1 4 ARG 4 40 40 ARG ARG B . n B 1 5 LYS 5 41 41 LYS LYS B . n B 1 6 THR 6 42 42 THR THR B . n B 1 7 TYR 7 43 43 TYR TYR B . n B 1 8 THR 8 44 44 THR THR B . n B 1 9 LEU 9 45 45 LEU LEU B . n B 1 10 THR 10 46 46 THR THR B . n B 1 11 ASP 11 47 47 ASP ASP B . n B 1 12 TYR 12 48 48 TYR TYR B . n B 1 13 LEU 13 49 49 LEU LEU B . n B 1 14 LYS 14 50 50 LYS LYS B . n B 1 15 ASN 15 51 51 ASN ASN B . n B 1 16 THR 16 52 52 THR THR B . n B 1 17 TYR 17 53 53 TYR TYR B . n B 1 18 ARG 18 54 54 ARG ARG B . n B 1 19 LEU 19 55 55 LEU LEU B . n B 1 20 LYS 20 56 56 LYS LYS B . n B 1 21 LEU 21 57 57 LEU LEU B . n B 1 22 TYR 22 58 58 TYR TYR B . n B 1 23 SER 23 59 59 SER SER B . n B 1 24 LEU 24 60 60 LEU LEU B . n B 1 25 ARG 25 61 61 ARG ARG B . n B 1 26 TRP 26 62 62 TRP TRP B . n B 1 27 ILE 27 63 63 ILE ILE B . n B 1 28 SER 28 64 64 SER SER B . n B 1 29 ASP 29 65 65 ASP ASP B . n B 1 30 HIS 30 66 66 HIS HIS B . n B 1 31 GLU 31 67 67 GLU GLU B . n B 1 32 TYR 32 68 68 TYR TYR B . n B 1 33 LEU 33 69 69 LEU LEU B . n B 1 34 TYR 34 70 70 TYR TYR B . n B 1 35 LYS 35 71 71 LYS LYS B . n B 1 36 GLN 36 72 72 GLN GLN B . n B 1 37 GLU 37 73 73 GLU GLU B . n B 1 38 ASN 38 74 74 ASN ASN B . n B 1 39 ASN 39 75 75 ASN ASN B . n B 1 40 ILE 40 76 76 ILE ILE B . n B 1 41 LEU 41 77 77 LEU LEU B . n B 1 42 VAL 42 78 78 VAL VAL B . n B 1 43 PHE 43 79 79 PHE PHE B . n B 1 44 ASN 44 80 80 ASN ASN B . n B 1 45 ALA 45 81 81 ALA ALA B . n B 1 46 GLU 46 82 82 GLU GLU B . n B 1 47 TYR 47 83 83 TYR TYR B . n B 1 48 GLY 48 84 84 GLY GLY B . n B 1 49 ASN 49 85 85 ASN ASN B . n B 1 50 SER 50 86 86 SER SER B . n B 1 51 SER 51 87 87 SER SER B . n B 1 52 VAL 52 88 88 VAL VAL B . n B 1 53 PHE 53 89 89 PHE PHE B . n B 1 54 LEU 54 90 90 LEU LEU B . n B 1 55 GLU 55 91 91 GLU GLU B . n B 1 56 ASN 56 92 92 ASN ASN B . n B 1 57 SER 57 93 93 SER SER B . n B 1 58 THR 58 94 94 THR THR B . n B 1 59 PHE 59 95 95 PHE PHE B . n B 1 60 ASP 60 96 96 ASP ASP B . n B 1 61 GLU 61 97 97 GLU GLU B . n B 1 62 PHE 62 98 98 PHE PHE B . n B 1 63 GLY 63 99 99 GLY GLY B . n B 1 64 HIS 64 100 100 HIS HIS B . n B 1 65 SER 65 101 101 SER SER B . n B 1 66 ILE 66 102 102 ILE ILE B . n B 1 67 ASN 67 103 103 ASN ASN B . n B 1 68 ASP 68 104 104 ASP ASP B . n B 1 69 TYR 69 105 105 TYR TYR B . n B 1 70 SER 70 106 106 SER SER B . n B 1 71 ILE 71 107 107 ILE ILE B . n B 1 72 SER 72 108 108 SER SER B . n B 1 73 PRO 73 109 109 PRO PRO B . n B 1 74 ASP 74 110 110 ASP ASP B . n B 1 75 GLY 75 111 111 GLY GLY B . n B 1 76 GLN 76 112 112 GLN GLN B . n B 1 77 PHE 77 113 113 PHE PHE B . n B 1 78 ILE 78 114 114 ILE ILE B . n B 1 79 LEU 79 115 115 LEU LEU B . n B 1 80 LEU 80 116 116 LEU LEU B . n B 1 81 GLU 81 117 117 GLU GLU B . n B 1 82 TYR 82 118 118 TYR TYR B . n B 1 83 ASN 83 119 119 ASN ASN B . n B 1 84 TYR 84 120 120 TYR TYR B . n B 1 85 VAL 85 121 121 VAL VAL B . n B 1 86 LYS 86 122 122 LYS LYS B . n B 1 87 GLN 87 123 123 GLN GLN B . n B 1 88 TRP 88 124 124 TRP TRP B . n B 1 89 ARG 89 125 125 ARG ARG B . n B 1 90 HIS 90 126 126 HIS HIS B . n B 1 91 SER 91 127 127 SER SER B . n B 1 92 TYR 92 128 128 TYR TYR B . n B 1 93 THR 93 129 129 THR THR B . n B 1 94 ALA 94 130 130 ALA ALA B . n B 1 95 SER 95 131 131 SER SER B . n B 1 96 TYR 96 132 132 TYR TYR B . n B 1 97 ASP 97 133 133 ASP ASP B . n B 1 98 ILE 98 134 134 ILE ILE B . n B 1 99 TYR 99 135 135 TYR TYR B . n B 1 100 ASP 100 136 136 ASP ASP B . n B 1 101 LEU 101 137 137 LEU LEU B . n B 1 102 ASN 102 138 138 ASN ASN B . n B 1 103 LYS 103 139 139 LYS LYS B . n B 1 104 ARG 104 140 140 ARG ARG B . n B 1 105 GLN 105 141 141 GLN GLN B . n B 1 106 LEU 106 142 142 LEU LEU B . n B 1 107 ILE 107 143 143 ILE ILE B . n B 1 108 THR 108 144 144 THR THR B . n B 1 109 GLU 109 145 145 GLU GLU B . n B 1 110 GLU 110 146 146 GLU GLU B . n B 1 111 ARG 111 147 147 ARG ARG B . n B 1 112 ILE 112 148 148 ILE ILE B . n B 1 113 PRO 113 149 149 PRO PRO B . n B 1 114 ASN 114 150 150 ASN ASN B . n B 1 115 ASN 115 151 151 ASN ASN B . n B 1 116 THR 116 152 152 THR THR B . n B 1 117 GLN 117 153 153 GLN GLN B . n B 1 118 TRP 118 154 154 TRP TRP B . n B 1 119 VAL 119 155 155 VAL VAL B . n B 1 120 THR 120 156 156 THR THR B . n B 1 121 TRP 121 157 157 TRP TRP B . n B 1 122 SER 122 158 158 SER SER B . n B 1 123 PRO 123 159 159 PRO PRO B . n B 1 124 VAL 124 160 160 VAL VAL B . n B 1 125 GLY 125 161 161 GLY GLY B . n B 1 126 HIS 126 162 162 HIS HIS B . n B 1 127 LYS 127 163 163 LYS LYS B . n B 1 128 LEU 128 164 164 LEU LEU B . n B 1 129 ALA 129 165 165 ALA ALA B . n B 1 130 TYR 130 166 166 TYR TYR B . n B 1 131 VAL 131 167 167 VAL VAL B . n B 1 132 TRP 132 168 168 TRP TRP B . n B 1 133 ASN 133 169 169 ASN ASN B . n B 1 134 ASN 134 170 170 ASN ASN B . n B 1 135 ASP 135 171 171 ASP ASP B . n B 1 136 ILE 136 172 172 ILE ILE B . n B 1 137 TYR 137 173 173 TYR TYR B . n B 1 138 VAL 138 174 174 VAL VAL B . n B 1 139 LYS 139 175 175 LYS LYS B . n B 1 140 ILE 140 176 176 ILE ILE B . n B 1 141 GLU 141 177 177 GLU GLU B . n B 1 142 PRO 142 178 178 PRO PRO B . n B 1 143 ASN 143 179 179 ASN ASN B . n B 1 144 LEU 144 180 180 LEU LEU B . n B 1 145 PRO 145 181 181 PRO PRO B . n B 1 146 SER 146 182 182 SER SER B . n B 1 147 TYR 147 183 183 TYR TYR B . n B 1 148 ARG 148 184 184 ARG ARG B . n B 1 149 ILE 149 185 185 ILE ILE B . n B 1 150 THR 150 186 186 THR THR B . n B 1 151 TRP 151 187 187 TRP TRP B . n B 1 152 THR 152 188 188 THR THR B . n B 1 153 GLY 153 189 189 GLY GLY B . n B 1 154 LYS 154 190 190 LYS LYS B . n B 1 155 GLU 155 191 191 GLU GLU B . n B 1 156 ASP 156 192 192 ASP ASP B . n B 1 157 ILE 157 193 193 ILE ILE B . n B 1 158 ILE 158 194 194 ILE ILE B . n B 1 159 TYR 159 195 195 TYR TYR B . n B 1 160 ASN 160 196 196 ASN ASN B . n B 1 161 GLY 161 197 197 GLY GLY B . n B 1 162 ILE 162 198 198 ILE ILE B . n B 1 163 THR 163 199 199 THR THR B . n B 1 164 ASP 164 200 200 ASP ASP B . n B 1 165 TRP 165 201 201 TRP TRP B . n B 1 166 VAL 166 202 202 VAL VAL B . n B 1 167 TYR 167 203 203 TYR TYR B . n B 1 168 GLU 168 204 204 GLU GLU B . n B 1 169 GLU 169 205 205 GLU GLU B . n B 1 170 GLU 170 206 206 GLU GLU B . n B 1 171 VAL 171 207 207 VAL VAL B . n B 1 172 PHE 172 208 208 PHE PHE B . n B 1 173 SER 173 209 209 SER SER B . n B 1 174 ALA 174 210 210 ALA ALA B . n B 1 175 TYR 175 211 211 TYR TYR B . n B 1 176 SER 176 212 212 SER SER B . n B 1 177 ALA 177 213 213 ALA ALA B . n B 1 178 LEU 178 214 214 LEU LEU B . n B 1 179 TRP 179 215 215 TRP TRP B . n B 1 180 TRP 180 216 216 TRP TRP B . n B 1 181 SER 181 217 217 SER SER B . n B 1 182 PRO 182 218 218 PRO PRO B . n B 1 183 ASN 183 219 219 ASN ASN B . n B 1 184 GLY 184 220 220 GLY GLY B . n B 1 185 THR 185 221 221 THR THR B . n B 1 186 PHE 186 222 222 PHE PHE B . n B 1 187 LEU 187 223 223 LEU LEU B . n B 1 188 ALA 188 224 224 ALA ALA B . n B 1 189 TYR 189 225 225 TYR TYR B . n B 1 190 ALA 190 226 226 ALA ALA B . n B 1 191 GLN 191 227 227 GLN GLN B . n B 1 192 PHE 192 228 228 PHE PHE B . n B 1 193 ASN 193 229 229 ASN ASN B . n B 1 194 ASP 194 230 230 ASP ASP B . n B 1 195 THR 195 231 231 THR THR B . n B 1 196 GLU 196 232 232 GLU GLU B . n B 1 197 VAL 197 233 233 VAL VAL B . n B 1 198 PRO 198 234 234 PRO PRO B . n B 1 199 LEU 199 235 235 LEU LEU B . n B 1 200 ILE 200 236 236 ILE ILE B . n B 1 201 GLU 201 237 237 GLU GLU B . n B 1 202 TYR 202 238 238 TYR TYR B . n B 1 203 SER 203 239 239 SER SER B . n B 1 204 PHE 204 240 240 PHE PHE B . n B 1 205 TYR 205 241 241 TYR TYR B . n B 1 206 SER 206 242 242 SER SER B . n B 1 207 ASP 207 243 243 ASP ASP B . n B 1 208 GLU 208 244 244 GLU GLU B . n B 1 209 SER 209 245 245 SER SER B . n B 1 210 LEU 210 246 246 LEU LEU B . n B 1 211 GLN 211 247 247 GLN GLN B . n B 1 212 TYR 212 248 248 TYR TYR B . n B 1 213 PRO 213 249 249 PRO PRO B . n B 1 214 LYS 214 250 250 LYS LYS B . n B 1 215 THR 215 251 251 THR THR B . n B 1 216 VAL 216 252 252 VAL VAL B . n B 1 217 ARG 217 253 253 ARG ARG B . n B 1 218 VAL 218 254 254 VAL VAL B . n B 1 219 PRO 219 255 255 PRO PRO B . n B 1 220 TYR 220 256 256 TYR TYR B . n B 1 221 PRO 221 257 257 PRO PRO B . n B 1 222 LYS 222 258 258 LYS LYS B . n B 1 223 ALA 223 259 259 ALA ALA B . n B 1 224 GLY 224 260 260 GLY GLY B . n B 1 225 ALA 225 261 261 ALA ALA B . n B 1 226 VAL 226 262 262 VAL VAL B . n B 1 227 ASN 227 263 263 ASN ASN B . n B 1 228 PRO 228 264 264 PRO PRO B . n B 1 229 THR 229 265 265 THR THR B . n B 1 230 VAL 230 266 266 VAL VAL B . n B 1 231 LYS 231 267 267 LYS LYS B . n B 1 232 PHE 232 268 268 PHE PHE B . n B 1 233 PHE 233 269 269 PHE PHE B . n B 1 234 VAL 234 270 270 VAL VAL B . n B 1 235 VAL 235 271 271 VAL VAL B . n B 1 236 ASN 236 272 272 ASN ASN B . n B 1 237 THR 237 273 273 THR THR B . n B 1 238 ASP 238 274 274 ASP ASP B . n B 1 239 SER 239 275 275 SER SER B . n B 1 240 LEU 240 276 276 LEU LEU B . n B 1 241 SER 241 277 277 SER SER B . n B 1 242 SER 242 278 278 SER SER B . n B 1 243 VAL 243 279 279 VAL VAL B . n B 1 244 THR 244 280 280 THR THR B . n B 1 245 ASN 245 281 281 ASN ASN B . n B 1 246 ALA 246 282 282 ALA ALA B . n B 1 247 THR 247 283 283 THR THR B . n B 1 248 SER 248 284 284 SER SER B . n B 1 249 ILE 249 285 285 ILE ILE B . n B 1 250 GLN 250 286 286 GLN GLN B . n B 1 251 ILE 251 287 287 ILE ILE B . n B 1 252 THR 252 288 288 THR THR B . n B 1 253 ALA 253 289 289 ALA ALA B . n B 1 254 PRO 254 290 290 PRO PRO B . n B 1 255 ALA 255 291 291 ALA ALA B . n B 1 256 SER 256 292 292 SER SER B . n B 1 257 MET 257 293 293 MET MET B . n B 1 258 LEU 258 294 294 LEU LEU B . n B 1 259 ILE 259 295 295 ILE ILE B . n B 1 260 GLY 260 296 296 GLY GLY B . n B 1 261 ASP 261 297 297 ASP ASP B . n B 1 262 HIS 262 298 298 HIS HIS B . n B 1 263 TYR 263 299 299 TYR TYR B . n B 1 264 LEU 264 300 300 LEU LEU B . n B 1 265 CYS 265 301 301 CYS CYS B . n B 1 266 ASP 266 302 302 ASP ASP B . n B 1 267 VAL 267 303 303 VAL VAL B . n B 1 268 THR 268 304 304 THR THR B . n B 1 269 TRP 269 305 305 TRP TRP B . n B 1 270 ALA 270 306 306 ALA ALA B . n B 1 271 THR 271 307 307 THR THR B . n B 1 272 GLN 272 308 308 GLN GLN B . n B 1 273 GLU 273 309 309 GLU GLU B . n B 1 274 ARG 274 310 310 ARG ARG B . n B 1 275 ILE 275 311 311 ILE ILE B . n B 1 276 SER 276 312 312 SER SER B . n B 1 277 LEU 277 313 313 LEU LEU B . n B 1 278 GLN 278 314 314 GLN GLN B . n B 1 279 TRP 279 315 315 TRP TRP B . n B 1 280 LEU 280 316 316 LEU LEU B . n B 1 281 ARG 281 317 317 ARG ARG B . n B 1 282 ARG 282 318 318 ARG ARG B . n B 1 283 ILE 283 319 319 ILE ILE B . n B 1 284 GLN 284 320 320 GLN GLN B . n B 1 285 ASN 285 321 321 ASN ASN B . n B 1 286 TYR 286 322 322 TYR TYR B . n B 1 287 SER 287 323 323 SER SER B . n B 1 288 VAL 288 324 324 VAL VAL B . n B 1 289 MET 289 325 325 MET MET B . n B 1 290 ASP 290 326 326 ASP ASP B . n B 1 291 ILE 291 327 327 ILE ILE B . n B 1 292 CYS 292 328 328 CYS CYS B . n B 1 293 ASP 293 329 329 ASP ASP B . n B 1 294 TYR 294 330 330 TYR TYR B . n B 1 295 ASP 295 331 331 ASP ASP B . n B 1 296 GLU 296 332 332 GLU GLU B . n B 1 297 SER 297 333 333 SER SER B . n B 1 298 SER 298 334 334 SER SER B . n B 1 299 GLY 299 335 335 GLY GLY B . n B 1 300 ARG 300 336 336 ARG ARG B . n B 1 301 TRP 301 337 337 TRP TRP B . n B 1 302 ASN 302 338 338 ASN ASN B . n B 1 303 CYS 303 339 339 CYS CYS B . n B 1 304 LEU 304 340 340 LEU LEU B . n B 1 305 VAL 305 341 341 VAL VAL B . n B 1 306 ALA 306 342 342 ALA ALA B . n B 1 307 ARG 307 343 343 ARG ARG B . n B 1 308 GLN 308 344 344 GLN GLN B . n B 1 309 HIS 309 345 345 HIS HIS B . n B 1 310 ILE 310 346 346 ILE ILE B . n B 1 311 GLU 311 347 347 GLU GLU B . n B 1 312 MET 312 348 348 MET MET B . n B 1 313 SER 313 349 349 SER SER B . n B 1 314 THR 314 350 350 THR THR B . n B 1 315 THR 315 351 351 THR THR B . n B 1 316 GLY 316 352 352 GLY GLY B . n B 1 317 TRP 317 353 353 TRP TRP B . n B 1 318 VAL 318 354 354 VAL VAL B . n B 1 319 GLY 319 355 355 GLY GLY B . n B 1 320 ARG 320 356 356 ARG ARG B . n B 1 321 PHE 321 357 357 PHE PHE B . n B 1 322 ARG 322 358 358 ARG ARG B . n B 1 323 PRO 323 359 359 PRO PRO B . n B 1 324 SER 324 360 360 SER SER B . n B 1 325 GLU 325 361 361 GLU GLU B . n B 1 326 PRO 326 362 362 PRO PRO B . n B 1 327 HIS 327 363 363 HIS HIS B . n B 1 328 PHE 328 364 364 PHE PHE B . n B 1 329 THR 329 365 365 THR THR B . n B 1 330 LEU 330 366 366 LEU LEU B . n B 1 331 ASP 331 367 367 ASP ASP B . n B 1 332 GLY 332 368 368 GLY GLY B . n B 1 333 ASN 333 369 369 ASN ASN B . n B 1 334 SER 334 370 370 SER SER B . n B 1 335 PHE 335 371 371 PHE PHE B . n B 1 336 TYR 336 372 372 TYR TYR B . n B 1 337 LYS 337 373 373 LYS LYS B . n B 1 338 ILE 338 374 374 ILE ILE B . n B 1 339 ILE 339 375 375 ILE ILE B . n B 1 340 SER 340 376 376 SER SER B . n B 1 341 ASN 341 377 377 ASN ASN B . n B 1 342 GLU 342 378 378 GLU GLU B . n B 1 343 GLU 343 379 379 GLU GLU B . n B 1 344 GLY 344 380 380 GLY GLY B . n B 1 345 TYR 345 381 381 TYR TYR B . n B 1 346 ARG 346 382 382 ARG ARG B . n B 1 347 HIS 347 383 383 HIS HIS B . n B 1 348 ILE 348 384 384 ILE ILE B . n B 1 349 CYS 349 385 385 CYS CYS B . n B 1 350 TYR 350 386 386 TYR TYR B . n B 1 351 PHE 351 387 387 PHE PHE B . n B 1 352 GLN 352 388 388 GLN GLN B . n B 1 353 ILE 353 389 389 ILE ILE B . n B 1 354 ASP 354 390 390 ASP ASP B . n B 1 355 LYS 355 391 391 LYS LYS B . n B 1 356 LYS 356 392 392 LYS LYS B . n B 1 357 ASP 357 393 393 ASP ASP B . n B 1 358 CYS 358 394 394 CYS CYS B . n B 1 359 THR 359 395 395 THR THR B . n B 1 360 PHE 360 396 396 PHE PHE B . n B 1 361 ILE 361 397 397 ILE ILE B . n B 1 362 THR 362 398 398 THR THR B . n B 1 363 LYS 363 399 399 LYS LYS B . n B 1 364 GLY 364 400 400 GLY GLY B . n B 1 365 THR 365 401 401 THR THR B . n B 1 366 TRP 366 402 402 TRP TRP B . n B 1 367 GLU 367 403 403 GLU GLU B . n B 1 368 VAL 368 404 404 VAL VAL B . n B 1 369 ILE 369 405 405 ILE ILE B . n B 1 370 GLY 370 406 406 GLY GLY B . n B 1 371 ILE 371 407 407 ILE ILE B . n B 1 372 GLU 372 408 408 GLU GLU B . n B 1 373 ALA 373 409 409 ALA ALA B . n B 1 374 LEU 374 410 410 LEU LEU B . n B 1 375 THR 375 411 411 THR THR B . n B 1 376 SER 376 412 412 SER SER B . n B 1 377 ASP 377 413 413 ASP ASP B . n B 1 378 TYR 378 414 414 TYR TYR B . n B 1 379 LEU 379 415 415 LEU LEU B . n B 1 380 TYR 380 416 416 TYR TYR B . n B 1 381 TYR 381 417 417 TYR TYR B . n B 1 382 ILE 382 418 418 ILE ILE B . n B 1 383 SER 383 419 419 SER SER B . n B 1 384 ASN 384 420 420 ASN ASN B . n B 1 385 GLU 385 421 421 GLU GLU B . n B 1 386 TYR 386 422 422 TYR TYR B . n B 1 387 LYS 387 423 423 LYS LYS B . n B 1 388 GLY 388 424 424 GLY GLY B . n B 1 389 MET 389 425 425 MET MET B . n B 1 390 PRO 390 426 426 PRO PRO B . n B 1 391 GLY 391 427 427 GLY GLY B . n B 1 392 GLY 392 428 428 GLY GLY B . n B 1 393 ARG 393 429 429 ARG ARG B . n B 1 394 ASN 394 430 430 ASN ASN B . n B 1 395 LEU 395 431 431 LEU LEU B . n B 1 396 TYR 396 432 432 TYR TYR B . n B 1 397 LYS 397 433 433 LYS LYS B . n B 1 398 ILE 398 434 434 ILE ILE B . n B 1 399 GLN 399 435 435 GLN GLN B . n B 1 400 LEU 400 436 436 LEU LEU B . n B 1 401 SER 401 437 437 SER SER B . n B 1 402 ASP 402 438 438 ASP ASP B . n B 1 403 TYR 403 439 439 TYR TYR B . n B 1 404 THR 404 440 440 THR THR B . n B 1 405 LYS 405 441 441 LYS LYS B . n B 1 406 VAL 406 442 442 VAL VAL B . n B 1 407 THR 407 443 443 THR THR B . n B 1 408 CYS 408 444 444 CYS CYS B . n B 1 409 LEU 409 445 445 LEU LEU B . n B 1 410 SER 410 446 446 SER SER B . n B 1 411 CYS 411 447 447 CYS CYS B . n B 1 412 GLU 412 448 448 GLU GLU B . n B 1 413 LEU 413 449 449 LEU LEU B . n B 1 414 ASN 414 450 450 ASN ASN B . n B 1 415 PRO 415 451 451 PRO PRO B . n B 1 416 GLU 416 452 452 GLU GLU B . n B 1 417 ARG 417 453 453 ARG ARG B . n B 1 418 CYS 418 454 454 CYS CYS B . n B 1 419 GLN 419 455 455 GLN GLN B . n B 1 420 TYR 420 456 456 TYR TYR B . n B 1 421 TYR 421 457 457 TYR TYR B . n B 1 422 SER 422 458 458 SER SER B . n B 1 423 VAL 423 459 459 VAL VAL B . n B 1 424 SER 424 460 460 SER SER B . n B 1 425 PHE 425 461 461 PHE PHE B . n B 1 426 SER 426 462 462 SER SER B . n B 1 427 LYS 427 463 463 LYS LYS B . n B 1 428 GLU 428 464 464 GLU GLU B . n B 1 429 ALA 429 465 465 ALA ALA B . n B 1 430 LYS 430 466 466 LYS LYS B . n B 1 431 TYR 431 467 467 TYR TYR B . n B 1 432 TYR 432 468 468 TYR TYR B . n B 1 433 GLN 433 469 469 GLN GLN B . n B 1 434 LEU 434 470 470 LEU LEU B . n B 1 435 ARG 435 471 471 ARG ARG B . n B 1 436 CYS 436 472 472 CYS CYS B . n B 1 437 SER 437 473 473 SER SER B . n B 1 438 GLY 438 474 474 GLY GLY B . n B 1 439 PRO 439 475 475 PRO PRO B . n B 1 440 GLY 440 476 476 GLY GLY B . n B 1 441 LEU 441 477 477 LEU LEU B . n B 1 442 PRO 442 478 478 PRO PRO B . n B 1 443 LEU 443 479 479 LEU LEU B . n B 1 444 TYR 444 480 480 TYR TYR B . n B 1 445 THR 445 481 481 THR THR B . n B 1 446 LEU 446 482 482 LEU LEU B . n B 1 447 HIS 447 483 483 HIS HIS B . n B 1 448 SER 448 484 484 SER SER B . n B 1 449 SER 449 485 485 SER SER B . n B 1 450 VAL 450 486 486 VAL VAL B . n B 1 451 ASN 451 487 487 ASN ASN B . n B 1 452 ASP 452 488 488 ASP ASP B . n B 1 453 LYS 453 489 489 LYS LYS B . n B 1 454 GLY 454 490 490 GLY GLY B . n B 1 455 LEU 455 491 491 LEU LEU B . n B 1 456 ARG 456 492 492 ARG ARG B . n B 1 457 VAL 457 493 493 VAL VAL B . n B 1 458 LEU 458 494 494 LEU LEU B . n B 1 459 GLU 459 495 495 GLU GLU B . n B 1 460 ASP 460 496 496 ASP ASP B . n B 1 461 ASN 461 497 497 ASN ASN B . n B 1 462 SER 462 498 498 SER SER B . n B 1 463 ALA 463 499 499 ALA ALA B . n B 1 464 LEU 464 500 500 LEU LEU B . n B 1 465 ASP 465 501 501 ASP ASP B . n B 1 466 LYS 466 502 502 LYS LYS B . n B 1 467 MET 467 503 503 MET MET B . n B 1 468 LEU 468 504 504 LEU LEU B . n B 1 469 GLN 469 505 505 GLN GLN B . n B 1 470 ASN 470 506 506 ASN ASN B . n B 1 471 VAL 471 507 507 VAL VAL B . n B 1 472 GLN 472 508 508 GLN GLN B . n B 1 473 MET 473 509 509 MET MET B . n B 1 474 PRO 474 510 510 PRO PRO B . n B 1 475 SER 475 511 511 SER SER B . n B 1 476 LYS 476 512 512 LYS LYS B . n B 1 477 LYS 477 513 513 LYS LYS B . n B 1 478 LEU 478 514 514 LEU LEU B . n B 1 479 ASP 479 515 515 ASP ASP B . n B 1 480 PHE 480 516 516 PHE PHE B . n B 1 481 ILE 481 517 517 ILE ILE B . n B 1 482 ILE 482 518 518 ILE ILE B . n B 1 483 LEU 483 519 519 LEU LEU B . n B 1 484 ASN 484 520 520 ASN ASN B . n B 1 485 GLU 485 521 521 GLU GLU B . n B 1 486 THR 486 522 522 THR THR B . n B 1 487 LYS 487 523 523 LYS LYS B . n B 1 488 PHE 488 524 524 PHE PHE B . n B 1 489 TRP 489 525 525 TRP TRP B . n B 1 490 TYR 490 526 526 TYR TYR B . n B 1 491 GLN 491 527 527 GLN GLN B . n B 1 492 MET 492 528 528 MET MET B . n B 1 493 ILE 493 529 529 ILE ILE B . n B 1 494 LEU 494 530 530 LEU LEU B . n B 1 495 PRO 495 531 531 PRO PRO B . n B 1 496 PRO 496 532 532 PRO PRO B . n B 1 497 HIS 497 533 533 HIS HIS B . n B 1 498 PHE 498 534 534 PHE PHE B . n B 1 499 ASP 499 535 535 ASP ASP B . n B 1 500 LYS 500 536 536 LYS LYS B . n B 1 501 SER 501 537 537 SER SER B . n B 1 502 LYS 502 538 538 LYS LYS B . n B 1 503 LYS 503 539 539 LYS LYS B . n B 1 504 TYR 504 540 540 TYR TYR B . n B 1 505 PRO 505 541 541 PRO PRO B . n B 1 506 LEU 506 542 542 LEU LEU B . n B 1 507 LEU 507 543 543 LEU LEU B . n B 1 508 LEU 508 544 544 LEU LEU B . n B 1 509 ASP 509 545 545 ASP ASP B . n B 1 510 VAL 510 546 546 VAL VAL B . n B 1 511 TYR 511 547 547 TYR TYR B . n B 1 512 ALA 512 548 548 ALA ALA B . n B 1 513 GLY 513 549 549 GLY GLY B . n B 1 514 PRO 514 550 550 PRO PRO B . n B 1 515 CYS 515 551 551 CYS CYS B . n B 1 516 SER 516 552 552 SER SER B . n B 1 517 GLN 517 553 553 GLN GLN B . n B 1 518 LYS 518 554 554 LYS LYS B . n B 1 519 ALA 519 555 555 ALA ALA B . n B 1 520 ASP 520 556 556 ASP ASP B . n B 1 521 THR 521 557 557 THR THR B . n B 1 522 VAL 522 558 558 VAL VAL B . n B 1 523 PHE 523 559 559 PHE PHE B . n B 1 524 ARG 524 560 560 ARG ARG B . n B 1 525 LEU 525 561 561 LEU LEU B . n B 1 526 ASN 526 562 562 ASN ASN B . n B 1 527 TRP 527 563 563 TRP TRP B . n B 1 528 ALA 528 564 564 ALA ALA B . n B 1 529 THR 529 565 565 THR THR B . n B 1 530 TYR 530 566 566 TYR TYR B . n B 1 531 LEU 531 567 567 LEU LEU B . n B 1 532 ALA 532 568 568 ALA ALA B . n B 1 533 SER 533 569 569 SER SER B . n B 1 534 THR 534 570 570 THR THR B . n B 1 535 GLU 535 571 571 GLU GLU B . n B 1 536 ASN 536 572 572 ASN ASN B . n B 1 537 ILE 537 573 573 ILE ILE B . n B 1 538 ILE 538 574 574 ILE ILE B . n B 1 539 VAL 539 575 575 VAL VAL B . n B 1 540 ALA 540 576 576 ALA ALA B . n B 1 541 SER 541 577 577 SER SER B . n B 1 542 PHE 542 578 578 PHE PHE B . n B 1 543 ASP 543 579 579 ASP ASP B . n B 1 544 GLY 544 580 580 GLY GLY B . n B 1 545 ARG 545 581 581 ARG ARG B . n B 1 546 GLY 546 582 582 GLY GLY B . n B 1 547 SER 547 583 583 SER SER B . n B 1 548 GLY 548 584 584 GLY GLY B . n B 1 549 TYR 549 585 585 TYR TYR B . n B 1 550 GLN 550 586 586 GLN GLN B . n B 1 551 GLY 551 587 587 GLY GLY B . n B 1 552 ASP 552 588 588 ASP ASP B . n B 1 553 LYS 553 589 589 LYS LYS B . n B 1 554 ILE 554 590 590 ILE ILE B . n B 1 555 MET 555 591 591 MET MET B . n B 1 556 HIS 556 592 592 HIS HIS B . n B 1 557 ALA 557 593 593 ALA ALA B . n B 1 558 ILE 558 594 594 ILE ILE B . n B 1 559 ASN 559 595 595 ASN ASN B . n B 1 560 ARG 560 596 596 ARG ARG B . n B 1 561 ARG 561 597 597 ARG ARG B . n B 1 562 LEU 562 598 598 LEU LEU B . n B 1 563 GLY 563 599 599 GLY GLY B . n B 1 564 THR 564 600 600 THR THR B . n B 1 565 PHE 565 601 601 PHE PHE B . n B 1 566 GLU 566 602 602 GLU GLU B . n B 1 567 VAL 567 603 603 VAL VAL B . n B 1 568 GLU 568 604 604 GLU GLU B . n B 1 569 ASP 569 605 605 ASP ASP B . n B 1 570 GLN 570 606 606 GLN GLN B . n B 1 571 ILE 571 607 607 ILE ILE B . n B 1 572 GLU 572 608 608 GLU GLU B . n B 1 573 ALA 573 609 609 ALA ALA B . n B 1 574 ALA 574 610 610 ALA ALA B . n B 1 575 ARG 575 611 611 ARG ARG B . n B 1 576 GLN 576 612 612 GLN GLN B . n B 1 577 PHE 577 613 613 PHE PHE B . n B 1 578 SER 578 614 614 SER SER B . n B 1 579 LYS 579 615 615 LYS LYS B . n B 1 580 MET 580 616 616 MET MET B . n B 1 581 GLY 581 617 617 GLY GLY B . n B 1 582 PHE 582 618 618 PHE PHE B . n B 1 583 VAL 583 619 619 VAL VAL B . n B 1 584 ASP 584 620 620 ASP ASP B . n B 1 585 ASN 585 621 621 ASN ASN B . n B 1 586 LYS 586 622 622 LYS LYS B . n B 1 587 ARG 587 623 623 ARG ARG B . n B 1 588 ILE 588 624 624 ILE ILE B . n B 1 589 ALA 589 625 625 ALA ALA B . n B 1 590 ILE 590 626 626 ILE ILE B . n B 1 591 TRP 591 627 627 TRP TRP B . n B 1 592 GLY 592 628 628 GLY GLY B . n B 1 593 TRP 593 629 629 TRP TRP B . n B 1 594 SER 594 630 630 SER SER B . n B 1 595 TYR 595 631 631 TYR TYR B . n B 1 596 GLY 596 632 632 GLY GLY B . n B 1 597 GLY 597 633 633 GLY GLY B . n B 1 598 TYR 598 634 634 TYR TYR B . n B 1 599 VAL 599 635 635 VAL VAL B . n B 1 600 THR 600 636 636 THR THR B . n B 1 601 SER 601 637 637 SER SER B . n B 1 602 MET 602 638 638 MET MET B . n B 1 603 VAL 603 639 639 VAL VAL B . n B 1 604 LEU 604 640 640 LEU LEU B . n B 1 605 GLY 605 641 641 GLY GLY B . n B 1 606 SER 606 642 642 SER SER B . n B 1 607 GLY 607 643 643 GLY GLY B . n B 1 608 SER 608 644 644 SER SER B . n B 1 609 GLY 609 645 645 GLY GLY B . n B 1 610 VAL 610 646 646 VAL VAL B . n B 1 611 PHE 611 647 647 PHE PHE B . n B 1 612 LYS 612 648 648 LYS LYS B . n B 1 613 CYS 613 649 649 CYS CYS B . n B 1 614 GLY 614 650 650 GLY GLY B . n B 1 615 ILE 615 651 651 ILE ILE B . n B 1 616 ALA 616 652 652 ALA ALA B . n B 1 617 VAL 617 653 653 VAL VAL B . n B 1 618 ALA 618 654 654 ALA ALA B . n B 1 619 PRO 619 655 655 PRO PRO B . n B 1 620 VAL 620 656 656 VAL VAL B . n B 1 621 SER 621 657 657 SER SER B . n B 1 622 ARG 622 658 658 ARG ARG B . n B 1 623 TRP 623 659 659 TRP TRP B . n B 1 624 GLU 624 660 660 GLU GLU B . n B 1 625 TYR 625 661 661 TYR TYR B . n B 1 626 TYR 626 662 662 TYR TYR B . n B 1 627 ASP 627 663 663 ASP ASP B . n B 1 628 SER 628 664 664 SER SER B . n B 1 629 VAL 629 665 665 VAL VAL B . n B 1 630 TYR 630 666 666 TYR TYR B . n B 1 631 THR 631 667 667 THR THR B . n B 1 632 GLU 632 668 668 GLU GLU B . n B 1 633 ARG 633 669 669 ARG ARG B . n B 1 634 TYR 634 670 670 TYR TYR B . n B 1 635 MET 635 671 671 MET MET B . n B 1 636 GLY 636 672 672 GLY GLY B . n B 1 637 LEU 637 673 673 LEU LEU B . n B 1 638 PRO 638 674 674 PRO PRO B . n B 1 639 THR 639 675 675 THR THR B . n B 1 640 PRO 640 676 676 PRO PRO B . n B 1 641 GLU 641 677 677 GLU GLU B . n B 1 642 ASP 642 678 678 ASP ASP B . n B 1 643 ASN 643 679 679 ASN ASN B . n B 1 644 LEU 644 680 680 LEU LEU B . n B 1 645 ASP 645 681 681 ASP ASP B . n B 1 646 HIS 646 682 682 HIS HIS B . n B 1 647 TYR 647 683 683 TYR TYR B . n B 1 648 ARG 648 684 684 ARG ARG B . n B 1 649 ASN 649 685 685 ASN ASN B . n B 1 650 SER 650 686 686 SER SER B . n B 1 651 THR 651 687 687 THR THR B . n B 1 652 VAL 652 688 688 VAL VAL B . n B 1 653 MET 653 689 689 MET MET B . n B 1 654 SER 654 690 690 SER SER B . n B 1 655 ARG 655 691 691 ARG ARG B . n B 1 656 ALA 656 692 692 ALA ALA B . n B 1 657 GLU 657 693 693 GLU GLU B . n B 1 658 ASN 658 694 694 ASN ASN B . n B 1 659 PHE 659 695 695 PHE PHE B . n B 1 660 LYS 660 696 696 LYS LYS B . n B 1 661 GLN 661 697 697 GLN GLN B . n B 1 662 VAL 662 698 698 VAL VAL B . n B 1 663 GLU 663 699 699 GLU GLU B . n B 1 664 TYR 664 700 700 TYR TYR B . n B 1 665 LEU 665 701 701 LEU LEU B . n B 1 666 LEU 666 702 702 LEU LEU B . n B 1 667 ILE 667 703 703 ILE ILE B . n B 1 668 HIS 668 704 704 HIS HIS B . n B 1 669 GLY 669 705 705 GLY GLY B . n B 1 670 THR 670 706 706 THR THR B . n B 1 671 ALA 671 707 707 ALA ALA B . n B 1 672 ASP 672 708 708 ASP ASP B . n B 1 673 ASP 673 709 709 ASP ASP B . n B 1 674 ASN 674 710 710 ASN ASN B . n B 1 675 VAL 675 711 711 VAL VAL B . n B 1 676 HIS 676 712 712 HIS HIS B . n B 1 677 PHE 677 713 713 PHE PHE B . n B 1 678 GLN 678 714 714 GLN GLN B . n B 1 679 GLN 679 715 715 GLN GLN B . n B 1 680 SER 680 716 716 SER SER B . n B 1 681 ALA 681 717 717 ALA ALA B . n B 1 682 GLN 682 718 718 GLN GLN B . n B 1 683 ILE 683 719 719 ILE ILE B . n B 1 684 SER 684 720 720 SER SER B . n B 1 685 LYS 685 721 721 LYS LYS B . n B 1 686 ALA 686 722 722 ALA ALA B . n B 1 687 LEU 687 723 723 LEU LEU B . n B 1 688 VAL 688 724 724 VAL VAL B . n B 1 689 ASP 689 725 725 ASP ASP B . n B 1 690 VAL 690 726 726 VAL VAL B . n B 1 691 GLY 691 727 727 GLY GLY B . n B 1 692 VAL 692 728 728 VAL VAL B . n B 1 693 ASP 693 729 729 ASP ASP B . n B 1 694 PHE 694 730 730 PHE PHE B . n B 1 695 GLN 695 731 731 GLN GLN B . n B 1 696 ALA 696 732 732 ALA ALA B . n B 1 697 MET 697 733 733 MET MET B . n B 1 698 TRP 698 734 734 TRP TRP B . n B 1 699 TYR 699 735 735 TYR TYR B . n B 1 700 THR 700 736 736 THR THR B . n B 1 701 ASP 701 737 737 ASP ASP B . n B 1 702 GLU 702 738 738 GLU GLU B . n B 1 703 ASP 703 739 739 ASP ASP B . n B 1 704 HIS 704 740 740 HIS HIS B . n B 1 705 GLY 705 741 741 GLY GLY B . n B 1 706 ILE 706 742 742 ILE ILE B . n B 1 707 ALA 707 743 743 ALA ALA B . n B 1 708 SER 708 744 744 SER SER B . n B 1 709 SER 709 745 745 SER SER B . n B 1 710 THR 710 746 746 THR THR B . n B 1 711 ALA 711 747 747 ALA ALA B . n B 1 712 HIS 712 748 748 HIS HIS B . n B 1 713 GLN 713 749 749 GLN GLN B . n B 1 714 HIS 714 750 750 HIS HIS B . n B 1 715 ILE 715 751 751 ILE ILE B . n B 1 716 TYR 716 752 752 TYR TYR B . n B 1 717 THR 717 753 753 THR THR B . n B 1 718 HIS 718 754 754 HIS HIS B . n B 1 719 MET 719 755 755 MET MET B . n B 1 720 SER 720 756 756 SER SER B . n B 1 721 HIS 721 757 757 HIS HIS B . n B 1 722 PHE 722 758 758 PHE PHE B . n B 1 723 ILE 723 759 759 ILE ILE B . n B 1 724 LYS 724 760 760 LYS LYS B . n B 1 725 GLN 725 761 761 GLN GLN B . n B 1 726 CYS 726 762 762 CYS CYS B . n B 1 727 PHE 727 763 763 PHE PHE B . n B 1 728 SER 728 764 764 SER SER B . n B 1 729 LEU 729 765 765 LEU LEU B . n B 1 730 PRO 730 766 766 PRO PRO B . n B 1 731 PRO 731 767 ? ? ? B . n B 1 732 LEU 732 768 ? ? ? B . n B 1 733 GLU 733 769 ? ? ? B . n B 1 734 GLN 734 770 ? ? ? B . n B 1 735 LYS 735 771 ? ? ? B . n B 1 736 LEU 736 772 ? ? ? B . n B 1 737 ILE 737 773 ? ? ? B . n B 1 738 SER 738 774 ? ? ? B . n B 1 739 GLU 739 775 ? ? ? B . n B 1 740 GLU 740 776 ? ? ? B . n B 1 741 ASP 741 777 ? ? ? B . n B 1 742 LEU 742 778 ? ? ? B . n B 1 743 ASN 743 779 ? ? ? B . n B 1 744 SER 744 780 ? ? ? B . n B 1 745 ALA 745 781 ? ? ? B . n B 1 746 VAL 746 782 ? ? ? B . n B 1 747 ASP 747 783 ? ? ? B . n B 1 748 HIS 748 784 ? ? ? B . n B 1 749 HIS 749 785 ? ? ? B . n B 1 750 HIS 750 786 ? ? ? B . n B 1 751 HIS 751 787 ? ? ? B . n B 1 752 HIS 752 788 ? ? ? B . n B 1 753 HIS 753 789 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 851 851 NAG NAG A . D 2 NAG 1 1501 1501 NAG NAG A . E 2 NAG 1 2191 2191 NAG NAG A . F 2 NAG 1 2291 2291 NAG NAG A . G 2 NAG 2 2292 2292 NAG NAG A . H 2 NAG 1 2811 2811 NAG NAG A . I 2 NAG 1 5201 5201 NAG NAG A . J 3 KXB 1 1 1 KXB KXB A . K 2 NAG 1 851 851 NAG NAG B . L 2 NAG 1 921 921 NAG NAG B . M 2 NAG 1 1501 1501 NAG NAG B . N 2 NAG 1 2191 2191 NAG NAG B . O 2 NAG 1 2291 2291 NAG NAG B . P 2 NAG 2 2292 2292 NAG NAG B . Q 2 NAG 1 5201 5201 NAG NAG B . R 3 KXB 1 2 2 KXB KXB B . S 4 HOH 1 5 5 HOH HOH A . S 4 HOH 2 7 7 HOH HOH A . S 4 HOH 3 14 14 HOH HOH A . S 4 HOH 4 19 19 HOH HOH A . S 4 HOH 5 20 20 HOH HOH A . S 4 HOH 6 21 21 HOH HOH A . S 4 HOH 7 24 24 HOH HOH A . S 4 HOH 8 25 25 HOH HOH A . S 4 HOH 9 26 26 HOH HOH A . S 4 HOH 10 27 27 HOH HOH A . S 4 HOH 11 28 28 HOH HOH A . S 4 HOH 12 30 30 HOH HOH A . S 4 HOH 13 32 32 HOH HOH A . S 4 HOH 14 33 33 HOH HOH A . S 4 HOH 15 790 37 HOH HOH A . S 4 HOH 16 791 39 HOH HOH A . S 4 HOH 17 792 40 HOH HOH A . S 4 HOH 18 793 41 HOH HOH A . S 4 HOH 19 794 46 HOH HOH A . S 4 HOH 20 795 58 HOH HOH A . S 4 HOH 21 796 62 HOH HOH A . S 4 HOH 22 797 64 HOH HOH A . S 4 HOH 23 798 67 HOH HOH A . S 4 HOH 24 799 68 HOH HOH A . S 4 HOH 25 800 69 HOH HOH A . S 4 HOH 26 801 70 HOH HOH A . S 4 HOH 27 802 72 HOH HOH A . S 4 HOH 28 803 75 HOH HOH A . S 4 HOH 29 804 76 HOH HOH A . S 4 HOH 30 805 77 HOH HOH A . S 4 HOH 31 806 78 HOH HOH A . S 4 HOH 32 807 79 HOH HOH A . S 4 HOH 33 808 80 HOH HOH A . S 4 HOH 34 809 81 HOH HOH A . S 4 HOH 35 810 84 HOH HOH A . S 4 HOH 36 811 85 HOH HOH A . S 4 HOH 37 812 87 HOH HOH A . S 4 HOH 38 813 88 HOH HOH A . S 4 HOH 39 814 90 HOH HOH A . S 4 HOH 40 815 93 HOH HOH A . S 4 HOH 41 816 94 HOH HOH A . S 4 HOH 42 817 97 HOH HOH A . S 4 HOH 43 818 100 HOH HOH A . S 4 HOH 44 819 101 HOH HOH A . S 4 HOH 45 820 102 HOH HOH A . S 4 HOH 46 821 103 HOH HOH A . S 4 HOH 47 822 105 HOH HOH A . S 4 HOH 48 823 106 HOH HOH A . S 4 HOH 49 824 108 HOH HOH A . S 4 HOH 50 825 109 HOH HOH A . S 4 HOH 51 826 110 HOH HOH A . S 4 HOH 52 827 112 HOH HOH A . S 4 HOH 53 828 114 HOH HOH A . S 4 HOH 54 829 116 HOH HOH A . S 4 HOH 55 830 120 HOH HOH A . S 4 HOH 56 831 123 HOH HOH A . S 4 HOH 57 832 125 HOH HOH A . S 4 HOH 58 833 128 HOH HOH A . S 4 HOH 59 834 131 HOH HOH A . S 4 HOH 60 835 133 HOH HOH A . S 4 HOH 61 836 134 HOH HOH A . S 4 HOH 62 837 135 HOH HOH A . S 4 HOH 63 838 137 HOH HOH A . S 4 HOH 64 839 138 HOH HOH A . S 4 HOH 65 840 139 HOH HOH A . S 4 HOH 66 841 140 HOH HOH A . S 4 HOH 67 842 142 HOH HOH A . S 4 HOH 68 843 143 HOH HOH A . S 4 HOH 69 844 147 HOH HOH A . S 4 HOH 70 845 148 HOH HOH A . S 4 HOH 71 846 150 HOH HOH A . S 4 HOH 72 847 154 HOH HOH A . S 4 HOH 73 848 155 HOH HOH A . S 4 HOH 74 849 157 HOH HOH A . S 4 HOH 75 850 159 HOH HOH A . S 4 HOH 76 852 160 HOH HOH A . S 4 HOH 77 853 162 HOH HOH A . S 4 HOH 78 854 165 HOH HOH A . S 4 HOH 79 855 168 HOH HOH A . S 4 HOH 80 856 169 HOH HOH A . S 4 HOH 81 857 171 HOH HOH A . S 4 HOH 82 858 176 HOH HOH A . S 4 HOH 83 859 177 HOH HOH A . S 4 HOH 84 860 179 HOH HOH A . S 4 HOH 85 861 180 HOH HOH A . S 4 HOH 86 862 182 HOH HOH A . S 4 HOH 87 863 184 HOH HOH A . S 4 HOH 88 864 187 HOH HOH A . S 4 HOH 89 865 188 HOH HOH A . S 4 HOH 90 866 191 HOH HOH A . S 4 HOH 91 867 192 HOH HOH A . S 4 HOH 92 868 195 HOH HOH A . S 4 HOH 93 869 198 HOH HOH A . S 4 HOH 94 870 200 HOH HOH A . S 4 HOH 95 871 201 HOH HOH A . S 4 HOH 96 872 204 HOH HOH A . S 4 HOH 97 873 207 HOH HOH A . S 4 HOH 98 874 208 HOH HOH A . S 4 HOH 99 875 210 HOH HOH A . S 4 HOH 100 876 213 HOH HOH A . S 4 HOH 101 877 214 HOH HOH A . S 4 HOH 102 878 220 HOH HOH A . S 4 HOH 103 879 221 HOH HOH A . S 4 HOH 104 880 222 HOH HOH A . S 4 HOH 105 881 224 HOH HOH A . S 4 HOH 106 882 226 HOH HOH A . S 4 HOH 107 883 228 HOH HOH A . S 4 HOH 108 884 229 HOH HOH A . S 4 HOH 109 885 231 HOH HOH A . S 4 HOH 110 886 233 HOH HOH A . S 4 HOH 111 887 235 HOH HOH A . S 4 HOH 112 888 239 HOH HOH A . S 4 HOH 113 889 241 HOH HOH A . S 4 HOH 114 890 242 HOH HOH A . S 4 HOH 115 891 243 HOH HOH A . S 4 HOH 116 892 244 HOH HOH A . S 4 HOH 117 893 245 HOH HOH A . S 4 HOH 118 894 246 HOH HOH A . S 4 HOH 119 895 248 HOH HOH A . S 4 HOH 120 896 251 HOH HOH A . S 4 HOH 121 897 252 HOH HOH A . S 4 HOH 122 898 255 HOH HOH A . S 4 HOH 123 899 258 HOH HOH A . S 4 HOH 124 900 260 HOH HOH A . S 4 HOH 125 901 261 HOH HOH A . S 4 HOH 126 902 263 HOH HOH A . S 4 HOH 127 903 264 HOH HOH A . S 4 HOH 128 904 265 HOH HOH A . S 4 HOH 129 905 267 HOH HOH A . S 4 HOH 130 906 271 HOH HOH A . S 4 HOH 131 907 272 HOH HOH A . S 4 HOH 132 908 274 HOH HOH A . S 4 HOH 133 909 276 HOH HOH A . S 4 HOH 134 910 281 HOH HOH A . S 4 HOH 135 911 282 HOH HOH A . S 4 HOH 136 912 287 HOH HOH A . S 4 HOH 137 913 290 HOH HOH A . S 4 HOH 138 914 293 HOH HOH A . S 4 HOH 139 915 296 HOH HOH A . S 4 HOH 140 916 314 HOH HOH A . S 4 HOH 141 917 315 HOH HOH A . S 4 HOH 142 918 316 HOH HOH A . S 4 HOH 143 919 317 HOH HOH A . S 4 HOH 144 920 318 HOH HOH A . S 4 HOH 145 921 319 HOH HOH A . S 4 HOH 146 922 320 HOH HOH A . S 4 HOH 147 923 321 HOH HOH A . S 4 HOH 148 924 322 HOH HOH A . S 4 HOH 149 925 323 HOH HOH A . S 4 HOH 150 926 324 HOH HOH A . S 4 HOH 151 927 325 HOH HOH A . S 4 HOH 152 928 326 HOH HOH A . S 4 HOH 153 929 327 HOH HOH A . S 4 HOH 154 930 328 HOH HOH A . S 4 HOH 155 931 334 HOH HOH A . S 4 HOH 156 932 339 HOH HOH A . S 4 HOH 157 933 341 HOH HOH A . S 4 HOH 158 934 343 HOH HOH A . S 4 HOH 159 935 344 HOH HOH A . S 4 HOH 160 936 345 HOH HOH A . S 4 HOH 161 937 346 HOH HOH A . S 4 HOH 162 938 349 HOH HOH A . S 4 HOH 163 939 352 HOH HOH A . S 4 HOH 164 940 353 HOH HOH A . S 4 HOH 165 941 354 HOH HOH A . S 4 HOH 166 942 356 HOH HOH A . S 4 HOH 167 943 357 HOH HOH A . S 4 HOH 168 944 358 HOH HOH A . S 4 HOH 169 945 359 HOH HOH A . S 4 HOH 170 946 360 HOH HOH A . S 4 HOH 171 947 361 HOH HOH A . S 4 HOH 172 948 364 HOH HOH A . S 4 HOH 173 949 365 HOH HOH A . S 4 HOH 174 950 367 HOH HOH A . S 4 HOH 175 951 369 HOH HOH A . S 4 HOH 176 952 370 HOH HOH A . S 4 HOH 177 953 372 HOH HOH A . S 4 HOH 178 954 382 HOH HOH A . S 4 HOH 179 955 384 HOH HOH A . S 4 HOH 180 956 386 HOH HOH A . S 4 HOH 181 957 389 HOH HOH A . S 4 HOH 182 958 392 HOH HOH A . S 4 HOH 183 959 394 HOH HOH A . S 4 HOH 184 960 395 HOH HOH A . S 4 HOH 185 961 396 HOH HOH A . S 4 HOH 186 962 397 HOH HOH A . S 4 HOH 187 963 400 HOH HOH A . S 4 HOH 188 964 401 HOH HOH A . S 4 HOH 189 965 403 HOH HOH A . S 4 HOH 190 966 404 HOH HOH A . S 4 HOH 191 967 405 HOH HOH A . S 4 HOH 192 968 407 HOH HOH A . S 4 HOH 193 969 408 HOH HOH A . S 4 HOH 194 970 411 HOH HOH A . S 4 HOH 195 971 415 HOH HOH A . S 4 HOH 196 972 416 HOH HOH A . S 4 HOH 197 973 417 HOH HOH A . S 4 HOH 198 974 418 HOH HOH A . S 4 HOH 199 975 421 HOH HOH A . S 4 HOH 200 976 423 HOH HOH A . S 4 HOH 201 977 425 HOH HOH A . S 4 HOH 202 978 426 HOH HOH A . S 4 HOH 203 979 430 HOH HOH A . S 4 HOH 204 980 432 HOH HOH A . S 4 HOH 205 981 433 HOH HOH A . S 4 HOH 206 982 435 HOH HOH A . S 4 HOH 207 983 436 HOH HOH A . S 4 HOH 208 984 442 HOH HOH A . S 4 HOH 209 985 446 HOH HOH A . S 4 HOH 210 986 448 HOH HOH A . S 4 HOH 211 987 451 HOH HOH A . S 4 HOH 212 988 455 HOH HOH A . S 4 HOH 213 989 456 HOH HOH A . S 4 HOH 214 990 461 HOH HOH A . S 4 HOH 215 991 462 HOH HOH A . S 4 HOH 216 992 476 HOH HOH A . S 4 HOH 217 993 484 HOH HOH A . S 4 HOH 218 994 485 HOH HOH A . T 4 HOH 1 1 1 HOH HOH B . T 4 HOH 2 3 3 HOH HOH B . T 4 HOH 3 4 4 HOH HOH B . T 4 HOH 4 8 8 HOH HOH B . T 4 HOH 5 11 11 HOH HOH B . T 4 HOH 6 12 12 HOH HOH B . T 4 HOH 7 13 13 HOH HOH B . T 4 HOH 8 15 15 HOH HOH B . T 4 HOH 9 16 16 HOH HOH B . T 4 HOH 10 17 17 HOH HOH B . T 4 HOH 11 18 18 HOH HOH B . T 4 HOH 12 22 22 HOH HOH B . T 4 HOH 13 23 23 HOH HOH B . T 4 HOH 14 29 29 HOH HOH B . T 4 HOH 15 31 31 HOH HOH B . T 4 HOH 16 34 34 HOH HOH B . T 4 HOH 17 35 35 HOH HOH B . T 4 HOH 18 36 36 HOH HOH B . T 4 HOH 19 790 38 HOH HOH B . T 4 HOH 20 791 42 HOH HOH B . T 4 HOH 21 792 43 HOH HOH B . T 4 HOH 22 793 44 HOH HOH B . T 4 HOH 23 794 48 HOH HOH B . T 4 HOH 24 795 50 HOH HOH B . T 4 HOH 25 796 51 HOH HOH B . T 4 HOH 26 797 52 HOH HOH B . T 4 HOH 27 798 53 HOH HOH B . T 4 HOH 28 799 54 HOH HOH B . T 4 HOH 29 800 55 HOH HOH B . T 4 HOH 30 801 57 HOH HOH B . T 4 HOH 31 802 59 HOH HOH B . T 4 HOH 32 803 60 HOH HOH B . T 4 HOH 33 804 61 HOH HOH B . T 4 HOH 34 805 63 HOH HOH B . T 4 HOH 35 806 65 HOH HOH B . T 4 HOH 36 807 66 HOH HOH B . T 4 HOH 37 808 71 HOH HOH B . T 4 HOH 38 809 73 HOH HOH B . T 4 HOH 39 810 74 HOH HOH B . T 4 HOH 40 811 82 HOH HOH B . T 4 HOH 41 812 83 HOH HOH B . T 4 HOH 42 813 86 HOH HOH B . T 4 HOH 43 814 89 HOH HOH B . T 4 HOH 44 815 91 HOH HOH B . T 4 HOH 45 816 95 HOH HOH B . T 4 HOH 46 817 96 HOH HOH B . T 4 HOH 47 818 98 HOH HOH B . T 4 HOH 48 819 99 HOH HOH B . T 4 HOH 49 820 104 HOH HOH B . T 4 HOH 50 821 107 HOH HOH B . T 4 HOH 51 822 111 HOH HOH B . T 4 HOH 52 823 113 HOH HOH B . T 4 HOH 53 824 115 HOH HOH B . T 4 HOH 54 825 117 HOH HOH B . T 4 HOH 55 826 118 HOH HOH B . T 4 HOH 56 827 119 HOH HOH B . T 4 HOH 57 828 121 HOH HOH B . T 4 HOH 58 829 122 HOH HOH B . T 4 HOH 59 830 124 HOH HOH B . T 4 HOH 60 831 126 HOH HOH B . T 4 HOH 61 832 127 HOH HOH B . T 4 HOH 62 833 129 HOH HOH B . T 4 HOH 63 834 130 HOH HOH B . T 4 HOH 64 835 132 HOH HOH B . T 4 HOH 65 836 136 HOH HOH B . T 4 HOH 66 837 141 HOH HOH B . T 4 HOH 67 838 145 HOH HOH B . T 4 HOH 68 839 146 HOH HOH B . T 4 HOH 69 840 149 HOH HOH B . T 4 HOH 70 841 151 HOH HOH B . T 4 HOH 71 842 152 HOH HOH B . T 4 HOH 72 843 153 HOH HOH B . T 4 HOH 73 844 156 HOH HOH B . T 4 HOH 74 845 161 HOH HOH B . T 4 HOH 75 846 163 HOH HOH B . T 4 HOH 76 847 166 HOH HOH B . T 4 HOH 77 848 167 HOH HOH B . T 4 HOH 78 849 170 HOH HOH B . T 4 HOH 79 850 172 HOH HOH B . T 4 HOH 80 852 173 HOH HOH B . T 4 HOH 81 853 174 HOH HOH B . T 4 HOH 82 854 175 HOH HOH B . T 4 HOH 83 855 178 HOH HOH B . T 4 HOH 84 856 181 HOH HOH B . T 4 HOH 85 857 183 HOH HOH B . T 4 HOH 86 858 185 HOH HOH B . T 4 HOH 87 859 186 HOH HOH B . T 4 HOH 88 860 189 HOH HOH B . T 4 HOH 89 861 190 HOH HOH B . T 4 HOH 90 862 193 HOH HOH B . T 4 HOH 91 863 194 HOH HOH B . T 4 HOH 92 864 196 HOH HOH B . T 4 HOH 93 865 197 HOH HOH B . T 4 HOH 94 866 199 HOH HOH B . T 4 HOH 95 867 202 HOH HOH B . T 4 HOH 96 868 203 HOH HOH B . T 4 HOH 97 869 205 HOH HOH B . T 4 HOH 98 870 206 HOH HOH B . T 4 HOH 99 871 209 HOH HOH B . T 4 HOH 100 872 211 HOH HOH B . T 4 HOH 101 873 212 HOH HOH B . T 4 HOH 102 874 215 HOH HOH B . T 4 HOH 103 875 216 HOH HOH B . T 4 HOH 104 876 217 HOH HOH B . T 4 HOH 105 877 218 HOH HOH B . T 4 HOH 106 878 223 HOH HOH B . T 4 HOH 107 879 225 HOH HOH B . T 4 HOH 108 880 227 HOH HOH B . T 4 HOH 109 881 230 HOH HOH B . T 4 HOH 110 882 232 HOH HOH B . T 4 HOH 111 883 236 HOH HOH B . T 4 HOH 112 884 237 HOH HOH B . T 4 HOH 113 885 238 HOH HOH B . T 4 HOH 114 886 240 HOH HOH B . T 4 HOH 115 887 249 HOH HOH B . T 4 HOH 116 888 250 HOH HOH B . T 4 HOH 117 889 253 HOH HOH B . T 4 HOH 118 890 254 HOH HOH B . T 4 HOH 119 891 256 HOH HOH B . T 4 HOH 120 892 257 HOH HOH B . T 4 HOH 121 893 259 HOH HOH B . T 4 HOH 122 894 262 HOH HOH B . T 4 HOH 123 895 266 HOH HOH B . T 4 HOH 124 896 268 HOH HOH B . T 4 HOH 125 897 269 HOH HOH B . T 4 HOH 126 898 270 HOH HOH B . T 4 HOH 127 899 273 HOH HOH B . T 4 HOH 128 900 277 HOH HOH B . T 4 HOH 129 901 279 HOH HOH B . T 4 HOH 130 902 284 HOH HOH B . T 4 HOH 131 903 285 HOH HOH B . T 4 HOH 132 904 286 HOH HOH B . T 4 HOH 133 905 288 HOH HOH B . T 4 HOH 134 906 289 HOH HOH B . T 4 HOH 135 907 291 HOH HOH B . T 4 HOH 136 908 292 HOH HOH B . T 4 HOH 137 909 295 HOH HOH B . T 4 HOH 138 910 297 HOH HOH B . T 4 HOH 139 911 298 HOH HOH B . T 4 HOH 140 912 299 HOH HOH B . T 4 HOH 141 913 302 HOH HOH B . T 4 HOH 142 914 303 HOH HOH B . T 4 HOH 143 915 304 HOH HOH B . T 4 HOH 144 916 305 HOH HOH B . T 4 HOH 145 917 306 HOH HOH B . T 4 HOH 146 918 311 HOH HOH B . T 4 HOH 147 919 312 HOH HOH B . T 4 HOH 148 920 329 HOH HOH B . T 4 HOH 149 922 330 HOH HOH B . T 4 HOH 150 923 331 HOH HOH B . T 4 HOH 151 924 332 HOH HOH B . T 4 HOH 152 925 333 HOH HOH B . T 4 HOH 153 926 348 HOH HOH B . T 4 HOH 154 927 350 HOH HOH B . T 4 HOH 155 928 351 HOH HOH B . T 4 HOH 156 929 355 HOH HOH B . T 4 HOH 157 930 362 HOH HOH B . T 4 HOH 158 931 363 HOH HOH B . T 4 HOH 159 932 366 HOH HOH B . T 4 HOH 160 933 368 HOH HOH B . T 4 HOH 161 934 371 HOH HOH B . T 4 HOH 162 935 374 HOH HOH B . T 4 HOH 163 936 375 HOH HOH B . T 4 HOH 164 937 376 HOH HOH B . T 4 HOH 165 938 377 HOH HOH B . T 4 HOH 166 939 378 HOH HOH B . T 4 HOH 167 940 379 HOH HOH B . T 4 HOH 168 941 380 HOH HOH B . T 4 HOH 169 942 383 HOH HOH B . T 4 HOH 170 943 385 HOH HOH B . T 4 HOH 171 944 387 HOH HOH B . T 4 HOH 172 945 388 HOH HOH B . T 4 HOH 173 946 390 HOH HOH B . T 4 HOH 174 947 391 HOH HOH B . T 4 HOH 175 948 393 HOH HOH B . T 4 HOH 176 949 398 HOH HOH B . T 4 HOH 177 950 402 HOH HOH B . T 4 HOH 178 951 406 HOH HOH B . T 4 HOH 179 952 409 HOH HOH B . T 4 HOH 180 953 410 HOH HOH B . T 4 HOH 181 954 412 HOH HOH B . T 4 HOH 182 955 414 HOH HOH B . T 4 HOH 183 956 419 HOH HOH B . T 4 HOH 184 957 422 HOH HOH B . T 4 HOH 185 958 424 HOH HOH B . T 4 HOH 186 959 427 HOH HOH B . T 4 HOH 187 960 428 HOH HOH B . T 4 HOH 188 961 429 HOH HOH B . T 4 HOH 189 962 431 HOH HOH B . T 4 HOH 190 963 437 HOH HOH B . T 4 HOH 191 964 438 HOH HOH B . T 4 HOH 192 965 439 HOH HOH B . T 4 HOH 193 966 440 HOH HOH B . T 4 HOH 194 967 441 HOH HOH B . T 4 HOH 195 968 443 HOH HOH B . T 4 HOH 196 969 444 HOH HOH B . T 4 HOH 197 970 447 HOH HOH B . T 4 HOH 198 971 449 HOH HOH B . T 4 HOH 199 972 452 HOH HOH B . T 4 HOH 200 973 457 HOH HOH B . T 4 HOH 201 974 458 HOH HOH B . T 4 HOH 202 975 460 HOH HOH B . T 4 HOH 203 976 463 HOH HOH B . T 4 HOH 204 977 465 HOH HOH B . T 4 HOH 205 978 466 HOH HOH B . T 4 HOH 206 979 469 HOH HOH B . T 4 HOH 207 980 470 HOH HOH B . T 4 HOH 208 981 473 HOH HOH B . T 4 HOH 209 982 478 HOH HOH B . T 4 HOH 210 983 493 HOH HOH B . T 4 HOH 211 984 496 HOH HOH B . T 4 HOH 212 985 501 HOH HOH B . T 4 HOH 213 986 502 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 B ASN 484 B ASN 520 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 114 A ASN 150 ? ASN 'GLYCOSYLATION SITE' 3 B ASN 114 B ASN 150 ? ASN 'GLYCOSYLATION SITE' 4 B ASN 49 B ASN 85 ? ASN 'GLYCOSYLATION SITE' 5 A ASN 49 A ASN 85 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 183 B ASN 219 ? ASN 'GLYCOSYLATION SITE' 7 B ASN 193 B ASN 229 ? ASN 'GLYCOSYLATION SITE' 8 A ASN 484 A ASN 520 ? ASN 'GLYCOSYLATION SITE' 9 A ASN 183 A ASN 219 ? ASN 'GLYCOSYLATION SITE' 10 B ASN 56 B ASN 92 ? ASN 'GLYCOSYLATION SITE' 11 A ASN 193 A ASN 229 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 4350 ? 1 MORE -17 ? 1 'SSA (A^2)' 57750 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2011-10-26 2 'Structure model' 1 1 2012-05-23 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Database references' # loop_ _software.pdbx_ordinal _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id 1 PHENIX dev_613 ? package 'Paul D. Adams' PDAdams@lbl.gov refinement http://www.phenix-online.org/ C++ ? 2 PDB_EXTRACT 3.10 'June 10, 2010' package PDB deposit@deposit.rcsb.org 'data extraction' http://sw-tools.pdb.org/apps/PDB_EXTRACT/ C++ ? 3 CBASS . ? ? ? ? 'data collection' ? ? ? 4 HKL-2000 '(DENZO)' ? ? ? ? 'data reduction' ? ? ? 5 HKL-2000 '(SCALEPACK)' ? ? ? ? 'data scaling' ? ? ? 6 AMoRE . ? ? ? ? phasing ? ? ? # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OG B SER 462 ? ? O B HOH 802 ? ? 1.97 2 1 ND2 B ASN 92 ? ? C2 B NAG 921 ? ? 2.13 3 1 N B TYR 467 ? ? O B HOH 802 ? ? 2.15 4 1 O B GLY 161 ? ? O B HOH 800 ? ? 2.16 # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER A 64 ? ? -170.41 -168.85 2 1 ASN A 74 ? ? 57.11 13.61 3 1 GLN A 123 ? ? -112.43 -101.84 4 1 TRP A 124 ? ? -93.02 -144.57 5 1 HIS A 162 ? ? -150.43 33.23 6 1 ILE A 193 ? ? -126.02 -59.63 7 1 SER A 242 ? ? 66.79 -162.75 8 1 VAL A 279 ? ? -98.06 -66.32 9 1 THR A 307 ? ? -140.90 -159.04 10 1 GLN A 320 ? ? -79.99 45.74 11 1 ASP A 390 ? ? 82.50 5.81 12 1 ASP A 393 ? ? 63.49 -176.70 13 1 LYS A 423 ? ? 59.96 13.59 14 1 ASP A 438 ? ? -160.96 93.31 15 1 ASN A 450 ? ? -158.51 84.75 16 1 TYR A 547 ? ? -121.49 -74.96 17 1 ARG A 596 ? ? 57.24 11.69 18 1 THR A 600 ? ? -119.28 -92.60 19 1 SER A 630 ? ? 67.29 -124.97 20 1 ASP A 678 ? ? -105.13 -100.91 21 1 ASN A 710 ? ? -97.72 -72.28 22 1 GLN A 714 ? ? -39.02 -39.78 23 1 ASP A 739 ? ? -100.20 -155.00 24 1 ILE A 742 ? ? 35.85 56.23 25 1 SER B 64 ? ? -167.73 -166.04 26 1 HIS B 66 ? ? -140.61 -0.17 27 1 ASN B 74 ? ? 66.78 -4.12 28 1 GLN B 123 ? ? -110.66 -99.18 29 1 TRP B 124 ? ? -93.66 -144.62 30 1 ARG B 140 ? ? 39.10 58.39 31 1 HIS B 162 ? ? -151.88 38.58 32 1 ILE B 193 ? ? -125.12 -64.26 33 1 SER B 242 ? ? 62.71 -162.44 34 1 GLN B 320 ? ? -78.83 47.36 35 1 ASP B 393 ? ? 70.93 -163.18 36 1 LYS B 423 ? ? 54.99 17.81 37 1 ASN B 450 ? ? -157.42 78.60 38 1 TYR B 547 ? ? -118.83 -70.10 39 1 ARG B 597 ? ? -140.25 48.32 40 1 THR B 600 ? ? -119.14 -88.77 41 1 SER B 630 ? ? 65.14 -122.52 42 1 ASP B 678 ? ? -114.94 -102.20 43 1 ASN B 710 ? ? -103.30 -71.02 44 1 ASP B 739 ? ? -103.80 -156.74 45 1 ILE B 742 ? ? 37.13 58.53 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A ARG 40 ? CD ? A ARG 4 CD 2 1 Y 1 A ARG 40 ? NE ? A ARG 4 NE 3 1 Y 1 A ARG 40 ? CZ ? A ARG 4 CZ 4 1 Y 1 A ARG 40 ? NH1 ? A ARG 4 NH1 5 1 Y 1 A ARG 40 ? NH2 ? A ARG 4 NH2 6 1 Y 1 A ARG 54 ? NE ? A ARG 18 NE 7 1 Y 1 A ARG 54 ? CZ ? A ARG 18 CZ 8 1 Y 1 A ARG 54 ? NH1 ? A ARG 18 NH1 9 1 Y 1 A ARG 54 ? NH2 ? A ARG 18 NH2 10 1 Y 1 A LYS 71 ? CD ? A LYS 35 CD 11 1 Y 1 A LYS 71 ? CE ? A LYS 35 CE 12 1 Y 1 A LYS 71 ? NZ ? A LYS 35 NZ 13 1 Y 1 A GLU 91 ? CD ? A GLU 55 CD 14 1 Y 1 A GLU 91 ? OE1 ? A GLU 55 OE1 15 1 Y 1 A GLU 91 ? OE2 ? A GLU 55 OE2 16 1 Y 1 A LYS 139 ? CE ? A LYS 103 CE 17 1 Y 1 A LYS 139 ? NZ ? A LYS 103 NZ 18 1 Y 1 A ARG 140 ? NE ? A ARG 104 NE 19 1 Y 1 A ARG 140 ? CZ ? A ARG 104 CZ 20 1 Y 1 A ARG 140 ? NH1 ? A ARG 104 NH1 21 1 Y 1 A ARG 140 ? NH2 ? A ARG 104 NH2 22 1 Y 1 A LYS 175 ? CE ? A LYS 139 CE 23 1 Y 1 A LYS 175 ? NZ ? A LYS 139 NZ 24 1 Y 1 A ASN 179 ? O ? A ASN 143 O 25 1 Y 1 A ASP 243 ? OD1 ? A ASP 207 OD1 26 1 Y 1 A ASP 243 ? OD2 ? A ASP 207 OD2 27 1 Y 1 A LYS 250 ? CE ? A LYS 214 CE 28 1 Y 1 A LYS 250 ? NZ ? A LYS 214 NZ 29 1 Y 1 A GLU 332 ? CD ? A GLU 296 CD 30 1 Y 1 A GLU 332 ? OE1 ? A GLU 296 OE1 31 1 Y 1 A GLU 332 ? OE2 ? A GLU 296 OE2 32 1 Y 1 A GLU 378 ? CD ? A GLU 342 CD 33 1 Y 1 A GLU 378 ? OE1 ? A GLU 342 OE1 34 1 Y 1 A GLU 378 ? OE2 ? A GLU 342 OE2 35 1 Y 1 A LYS 391 ? NZ ? A LYS 355 NZ 36 1 Y 1 A LYS 392 ? CE ? A LYS 356 CE 37 1 Y 1 A LYS 392 ? NZ ? A LYS 356 NZ 38 1 Y 1 A LYS 441 ? CE ? A LYS 405 CE 39 1 Y 1 A LYS 441 ? NZ ? A LYS 405 NZ 40 1 Y 1 A LYS 463 ? CG ? A LYS 427 CG 41 1 Y 1 A LYS 463 ? CD ? A LYS 427 CD 42 1 Y 1 A LYS 463 ? CE ? A LYS 427 CE 43 1 Y 1 A LYS 463 ? NZ ? A LYS 427 NZ 44 1 Y 1 A LYS 466 ? CG ? A LYS 430 CG 45 1 Y 1 A LYS 466 ? CD ? A LYS 430 CD 46 1 Y 1 A LYS 466 ? CE ? A LYS 430 CE 47 1 Y 1 A LYS 466 ? NZ ? A LYS 430 NZ 48 1 Y 1 A LYS 502 ? CG ? A LYS 466 CG 49 1 Y 1 A LYS 502 ? CD ? A LYS 466 CD 50 1 Y 1 A LYS 502 ? CE ? A LYS 466 CE 51 1 Y 1 A LYS 502 ? NZ ? A LYS 466 NZ 52 1 Y 1 A LYS 513 ? CE ? A LYS 477 CE 53 1 Y 1 A LYS 513 ? NZ ? A LYS 477 NZ 54 1 Y 1 A LYS 589 ? CE ? A LYS 553 CE 55 1 Y 1 A LYS 589 ? NZ ? A LYS 553 NZ 56 1 Y 1 A LYS 696 ? CD ? A LYS 660 CD 57 1 Y 1 A LYS 696 ? CE ? A LYS 660 CE 58 1 Y 1 A LYS 696 ? NZ ? A LYS 660 NZ 59 1 Y 1 A GLN 761 ? CD ? A GLN 725 CD 60 1 Y 1 A GLN 761 ? OE1 ? A GLN 725 OE1 61 1 Y 1 A GLN 761 ? NE2 ? A GLN 725 NE2 62 1 Y 1 B ARG 40 ? NE ? B ARG 4 NE 63 1 Y 1 B ARG 40 ? CZ ? B ARG 4 CZ 64 1 Y 1 B ARG 40 ? NH1 ? B ARG 4 NH1 65 1 Y 1 B ARG 40 ? NH2 ? B ARG 4 NH2 66 1 Y 1 B LYS 41 ? CD ? B LYS 5 CD 67 1 Y 1 B LYS 41 ? CE ? B LYS 5 CE 68 1 Y 1 B LYS 41 ? NZ ? B LYS 5 NZ 69 1 Y 1 B ARG 54 ? NH1 ? B ARG 18 NH1 70 1 Y 1 B ARG 54 ? NH2 ? B ARG 18 NH2 71 1 Y 1 B LEU 90 ? CD1 ? B LEU 54 CD1 72 1 Y 1 B LEU 90 ? CD2 ? B LEU 54 CD2 73 1 Y 1 B GLU 97 ? CD ? B GLU 61 CD 74 1 Y 1 B GLU 97 ? OE1 ? B GLU 61 OE1 75 1 Y 1 B GLU 97 ? OE2 ? B GLU 61 OE2 76 1 Y 1 B LYS 139 ? CD ? B LYS 103 CD 77 1 Y 1 B LYS 139 ? CE ? B LYS 103 CE 78 1 Y 1 B LYS 139 ? NZ ? B LYS 103 NZ 79 1 Y 1 B ARG 140 ? CD ? B ARG 104 CD 80 1 Y 1 B ARG 140 ? NE ? B ARG 104 NE 81 1 Y 1 B ARG 140 ? CZ ? B ARG 104 CZ 82 1 Y 1 B ARG 140 ? NH1 ? B ARG 104 NH1 83 1 Y 1 B ARG 140 ? NH2 ? B ARG 104 NH2 84 1 Y 1 B ILE 143 ? CD1 ? B ILE 107 CD1 85 1 Y 1 B ARG 147 ? NH1 ? B ARG 111 NH1 86 1 Y 1 B ARG 147 ? NH2 ? B ARG 111 NH2 87 1 Y 1 B LYS 190 ? CE ? B LYS 154 CE 88 1 Y 1 B LYS 190 ? NZ ? B LYS 154 NZ 89 1 Y 1 B LYS 250 ? CE ? B LYS 214 CE 90 1 Y 1 B LYS 250 ? NZ ? B LYS 214 NZ 91 1 Y 1 B SER 278 ? OG ? B SER 242 OG 92 1 Y 1 B VAL 279 ? CG1 ? B VAL 243 CG1 93 1 Y 1 B VAL 279 ? CG2 ? B VAL 243 CG2 94 1 Y 1 B GLU 332 ? CG ? B GLU 296 CG 95 1 Y 1 B GLU 332 ? CD ? B GLU 296 CD 96 1 Y 1 B GLU 332 ? OE1 ? B GLU 296 OE1 97 1 Y 1 B GLU 332 ? OE2 ? B GLU 296 OE2 98 1 Y 1 B LEU 340 ? CD1 ? B LEU 304 CD1 99 1 Y 1 B LEU 340 ? CD2 ? B LEU 304 CD2 100 1 Y 1 B LYS 391 ? CE ? B LYS 355 CE 101 1 Y 1 B LYS 391 ? NZ ? B LYS 355 NZ 102 1 Y 1 B LYS 392 ? CD ? B LYS 356 CD 103 1 Y 1 B LYS 392 ? CE ? B LYS 356 CE 104 1 Y 1 B LYS 392 ? NZ ? B LYS 356 NZ 105 1 Y 1 B LYS 441 ? NZ ? B LYS 405 NZ 106 1 Y 1 B GLU 452 ? CG ? B GLU 416 CG 107 1 Y 1 B GLU 452 ? CD ? B GLU 416 CD 108 1 Y 1 B GLU 452 ? OE1 ? B GLU 416 OE1 109 1 Y 1 B GLU 452 ? OE2 ? B GLU 416 OE2 110 1 Y 1 B LYS 463 ? CE ? B LYS 427 CE 111 1 Y 1 B LYS 463 ? NZ ? B LYS 427 NZ 112 1 Y 1 B ARG 471 ? CD ? B ARG 435 CD 113 1 Y 1 B ARG 471 ? NE ? B ARG 435 NE 114 1 Y 1 B ARG 471 ? CZ ? B ARG 435 CZ 115 1 Y 1 B ARG 471 ? NH1 ? B ARG 435 NH1 116 1 Y 1 B ARG 471 ? NH2 ? B ARG 435 NH2 117 1 Y 1 B LYS 489 ? NZ ? B LYS 453 NZ 118 1 Y 1 B LYS 536 ? CG ? B LYS 500 CG 119 1 Y 1 B LYS 536 ? CD ? B LYS 500 CD 120 1 Y 1 B LYS 536 ? CE ? B LYS 500 CE 121 1 Y 1 B LYS 536 ? NZ ? B LYS 500 NZ 122 1 Y 1 B LYS 589 ? CE ? B LYS 553 CE 123 1 Y 1 B LYS 589 ? NZ ? B LYS 553 NZ 124 1 Y 1 B GLN 761 ? CD ? B GLN 725 CD 125 1 Y 1 B GLN 761 ? OE1 ? B GLN 725 OE1 126 1 Y 1 B GLN 761 ? NE2 ? B GLN 725 NE2 127 1 N 1 A NAG 2811 ? O1 ? G NAG 1 O1 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLU 37 ? A GLU 1 2 1 Y 1 A PHE 38 ? A PHE 2 3 1 Y 1 A SER 39 ? A SER 3 4 1 Y 1 A PRO 767 ? A PRO 731 5 1 Y 1 A LEU 768 ? A LEU 732 6 1 Y 1 A GLU 769 ? A GLU 733 7 1 Y 1 A GLN 770 ? A GLN 734 8 1 Y 1 A LYS 771 ? A LYS 735 9 1 Y 1 A LEU 772 ? A LEU 736 10 1 Y 1 A ILE 773 ? A ILE 737 11 1 Y 1 A SER 774 ? A SER 738 12 1 Y 1 A GLU 775 ? A GLU 739 13 1 Y 1 A GLU 776 ? A GLU 740 14 1 Y 1 A ASP 777 ? A ASP 741 15 1 Y 1 A LEU 778 ? A LEU 742 16 1 Y 1 A ASN 779 ? A ASN 743 17 1 Y 1 A SER 780 ? A SER 744 18 1 Y 1 A ALA 781 ? A ALA 745 19 1 Y 1 A VAL 782 ? A VAL 746 20 1 Y 1 A ASP 783 ? A ASP 747 21 1 Y 1 A HIS 784 ? A HIS 748 22 1 Y 1 A HIS 785 ? A HIS 749 23 1 Y 1 A HIS 786 ? A HIS 750 24 1 Y 1 A HIS 787 ? A HIS 751 25 1 Y 1 A HIS 788 ? A HIS 752 26 1 Y 1 A HIS 789 ? A HIS 753 27 1 Y 1 B GLU 37 ? B GLU 1 28 1 Y 1 B PHE 38 ? B PHE 2 29 1 Y 1 B SER 39 ? B SER 3 30 1 Y 1 B PRO 767 ? B PRO 731 31 1 Y 1 B LEU 768 ? B LEU 732 32 1 Y 1 B GLU 769 ? B GLU 733 33 1 Y 1 B GLN 770 ? B GLN 734 34 1 Y 1 B LYS 771 ? B LYS 735 35 1 Y 1 B LEU 772 ? B LEU 736 36 1 Y 1 B ILE 773 ? B ILE 737 37 1 Y 1 B SER 774 ? B SER 738 38 1 Y 1 B GLU 775 ? B GLU 739 39 1 Y 1 B GLU 776 ? B GLU 740 40 1 Y 1 B ASP 777 ? B ASP 741 41 1 Y 1 B LEU 778 ? B LEU 742 42 1 Y 1 B ASN 779 ? B ASN 743 43 1 Y 1 B SER 780 ? B SER 744 44 1 Y 1 B ALA 781 ? B ALA 745 45 1 Y 1 B VAL 782 ? B VAL 746 46 1 Y 1 B ASP 783 ? B ASP 747 47 1 Y 1 B HIS 784 ? B HIS 748 48 1 Y 1 B HIS 785 ? B HIS 749 49 1 Y 1 B HIS 786 ? B HIS 750 50 1 Y 1 B HIS 787 ? B HIS 751 51 1 Y 1 B HIS 788 ? B HIS 752 52 1 Y 1 B HIS 789 ? B HIS 753 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 '3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyethyl)-2-methyl-5,6-dihydro-7H-pyrrolo[3,4-b]pyridin-7-one' KXB 4 water HOH #