data_3LGG # _entry.id 3LGG # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3LGG RCSB RCSB057247 WWPDB D_1000057247 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 3LGD _pdbx_database_related.details ;Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2), apo enzyme ; _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3LGG _pdbx_database_status.recvd_initial_deposition_date 2010-01-20 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # _audit_author.name 'Zavialov, A.V.' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title 'Structural basis for the growth factor activity of human adenosine deaminase ADA2.' _citation.journal_abbrev J.Biol.Chem. _citation.journal_volume 285 _citation.page_first 12367 _citation.page_last 12377 _citation.year 2010 _citation.journal_id_ASTM JBCHA3 _citation.country US _citation.journal_id_ISSN 0021-9258 _citation.journal_id_CSD 0071 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20147294 _citation.pdbx_database_id_DOI 10.1074/jbc.M109.083527 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Zavialov, A.V.' 1 primary 'Yu, X.' 2 primary 'Spillmann, D.' 3 primary 'Lauvau, G.' 4 primary 'Zavialov, A.V.' 5 # _cell.entry_id 3LGG _cell.length_a 63.249 _cell.length_b 72.993 _cell.length_c 80.537 _cell.angle_alpha 113.55 _cell.angle_beta 94.89 _cell.angle_gamma 91.53 _cell.Z_PDB 2 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3LGG _symmetry.space_group_name_H-M 'P 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 1 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Adenosine deaminase CECR1' 59049.293 2 3.5.4.4 ? ? ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 6 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 2 ? ? ? ? 4 non-polymer syn '(8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol' 284.269 2 ? ? ? ? 5 water nat water 18.015 244 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Cat eye syndrome critical region protein 1' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;GGSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMP KGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNF TLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSV KTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAK DGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPV ATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIA DVATKGSLHHILDAQKMVWNHRHHHHHH ; _entity_poly.pdbx_seq_one_letter_code_can ;GGSIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMP KGAALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNF TLVTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSV KTYQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAK DGVKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPV ATLMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIA DVATKGSLHHILDAQKMVWNHRHHHHHH ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 GLY n 1 3 SER n 1 4 ILE n 1 5 ASP n 1 6 GLU n 1 7 THR n 1 8 ARG n 1 9 ALA n 1 10 HIS n 1 11 LEU n 1 12 LEU n 1 13 LEU n 1 14 LYS n 1 15 GLU n 1 16 LYS n 1 17 MET n 1 18 MET n 1 19 ARG n 1 20 LEU n 1 21 GLY n 1 22 GLY n 1 23 ARG n 1 24 LEU n 1 25 VAL n 1 26 LEU n 1 27 ASN n 1 28 THR n 1 29 LYS n 1 30 GLU n 1 31 GLU n 1 32 LEU n 1 33 ALA n 1 34 ASN n 1 35 GLU n 1 36 ARG n 1 37 LEU n 1 38 MET n 1 39 THR n 1 40 LEU n 1 41 LYS n 1 42 ILE n 1 43 ALA n 1 44 GLU n 1 45 MET n 1 46 LYS n 1 47 GLU n 1 48 ALA n 1 49 MET n 1 50 ARG n 1 51 THR n 1 52 LEU n 1 53 ILE n 1 54 PHE n 1 55 PRO n 1 56 PRO n 1 57 SER n 1 58 MET n 1 59 HIS n 1 60 PHE n 1 61 PHE n 1 62 GLN n 1 63 ALA n 1 64 LYS n 1 65 HIS n 1 66 LEU n 1 67 ILE n 1 68 GLU n 1 69 ARG n 1 70 SER n 1 71 GLN n 1 72 VAL n 1 73 PHE n 1 74 ASN n 1 75 ILE n 1 76 LEU n 1 77 ARG n 1 78 MET n 1 79 MET n 1 80 PRO n 1 81 LYS n 1 82 GLY n 1 83 ALA n 1 84 ALA n 1 85 LEU n 1 86 HIS n 1 87 LEU n 1 88 HIS n 1 89 ASP n 1 90 ILE n 1 91 GLY n 1 92 ILE n 1 93 VAL n 1 94 THR n 1 95 MET n 1 96 ASP n 1 97 TRP n 1 98 LEU n 1 99 VAL n 1 100 ARG n 1 101 ASN n 1 102 VAL n 1 103 THR n 1 104 TYR n 1 105 ARG n 1 106 PRO n 1 107 HIS n 1 108 CYS n 1 109 HIS n 1 110 ILE n 1 111 CYS n 1 112 PHE n 1 113 THR n 1 114 PRO n 1 115 ARG n 1 116 GLY n 1 117 ILE n 1 118 MET n 1 119 GLN n 1 120 PHE n 1 121 ARG n 1 122 PHE n 1 123 ALA n 1 124 HIS n 1 125 PRO n 1 126 THR n 1 127 PRO n 1 128 ARG n 1 129 PRO n 1 130 SER n 1 131 GLU n 1 132 LYS n 1 133 CYS n 1 134 SER n 1 135 LYS n 1 136 TRP n 1 137 ILE n 1 138 LEU n 1 139 LEU n 1 140 GLU n 1 141 ASP n 1 142 TYR n 1 143 ARG n 1 144 LYS n 1 145 ARG n 1 146 VAL n 1 147 GLN n 1 148 ASN n 1 149 VAL n 1 150 THR n 1 151 GLU n 1 152 PHE n 1 153 ASP n 1 154 ASP n 1 155 SER n 1 156 LEU n 1 157 LEU n 1 158 ARG n 1 159 ASN n 1 160 PHE n 1 161 THR n 1 162 LEU n 1 163 VAL n 1 164 THR n 1 165 GLN n 1 166 HIS n 1 167 PRO n 1 168 GLU n 1 169 VAL n 1 170 ILE n 1 171 TYR n 1 172 THR n 1 173 ASN n 1 174 GLN n 1 175 ASN n 1 176 VAL n 1 177 VAL n 1 178 TRP n 1 179 SER n 1 180 LYS n 1 181 PHE n 1 182 GLU n 1 183 THR n 1 184 ILE n 1 185 PHE n 1 186 PHE n 1 187 THR n 1 188 ILE n 1 189 SER n 1 190 GLY n 1 191 LEU n 1 192 ILE n 1 193 HIS n 1 194 TYR n 1 195 ALA n 1 196 PRO n 1 197 VAL n 1 198 PHE n 1 199 ARG n 1 200 ASP n 1 201 TYR n 1 202 VAL n 1 203 PHE n 1 204 ARG n 1 205 SER n 1 206 MET n 1 207 GLN n 1 208 GLU n 1 209 PHE n 1 210 TYR n 1 211 GLU n 1 212 ASP n 1 213 ASN n 1 214 VAL n 1 215 LEU n 1 216 TYR n 1 217 MET n 1 218 GLU n 1 219 ILE n 1 220 ARG n 1 221 ALA n 1 222 ARG n 1 223 LEU n 1 224 LEU n 1 225 PRO n 1 226 VAL n 1 227 TYR n 1 228 GLU n 1 229 LEU n 1 230 SER n 1 231 GLY n 1 232 GLU n 1 233 HIS n 1 234 HIS n 1 235 ASP n 1 236 GLU n 1 237 GLU n 1 238 TRP n 1 239 SER n 1 240 VAL n 1 241 LYS n 1 242 THR n 1 243 TYR n 1 244 GLN n 1 245 GLU n 1 246 VAL n 1 247 ALA n 1 248 GLN n 1 249 LYS n 1 250 PHE n 1 251 VAL n 1 252 GLU n 1 253 THR n 1 254 HIS n 1 255 PRO n 1 256 GLU n 1 257 PHE n 1 258 ILE n 1 259 GLY n 1 260 ILE n 1 261 LYS n 1 262 ILE n 1 263 ILE n 1 264 TYR n 1 265 SER n 1 266 ASP n 1 267 HIS n 1 268 ARG n 1 269 SER n 1 270 LYS n 1 271 ASP n 1 272 VAL n 1 273 ALA n 1 274 VAL n 1 275 ILE n 1 276 ALA n 1 277 GLU n 1 278 SER n 1 279 ILE n 1 280 ARG n 1 281 MET n 1 282 ALA n 1 283 MET n 1 284 GLY n 1 285 LEU n 1 286 ARG n 1 287 ILE n 1 288 LYS n 1 289 PHE n 1 290 PRO n 1 291 THR n 1 292 VAL n 1 293 VAL n 1 294 ALA n 1 295 GLY n 1 296 PHE n 1 297 ASP n 1 298 LEU n 1 299 VAL n 1 300 GLY n 1 301 HIS n 1 302 GLU n 1 303 ASP n 1 304 THR n 1 305 GLY n 1 306 HIS n 1 307 SER n 1 308 LEU n 1 309 HIS n 1 310 ASP n 1 311 TYR n 1 312 LYS n 1 313 GLU n 1 314 ALA n 1 315 LEU n 1 316 MET n 1 317 ILE n 1 318 PRO n 1 319 ALA n 1 320 LYS n 1 321 ASP n 1 322 GLY n 1 323 VAL n 1 324 LYS n 1 325 LEU n 1 326 PRO n 1 327 TYR n 1 328 PHE n 1 329 PHE n 1 330 HIS n 1 331 ALA n 1 332 GLY n 1 333 GLU n 1 334 THR n 1 335 ASP n 1 336 TRP n 1 337 GLN n 1 338 GLY n 1 339 THR n 1 340 SER n 1 341 ILE n 1 342 ASP n 1 343 ARG n 1 344 ASN n 1 345 ILE n 1 346 LEU n 1 347 ASP n 1 348 ALA n 1 349 LEU n 1 350 MET n 1 351 LEU n 1 352 ASN n 1 353 THR n 1 354 THR n 1 355 ARG n 1 356 ILE n 1 357 GLY n 1 358 HIS n 1 359 GLY n 1 360 PHE n 1 361 ALA n 1 362 LEU n 1 363 SER n 1 364 LYS n 1 365 HIS n 1 366 PRO n 1 367 ALA n 1 368 VAL n 1 369 ARG n 1 370 THR n 1 371 TYR n 1 372 SER n 1 373 TRP n 1 374 LYS n 1 375 LYS n 1 376 ASP n 1 377 ILE n 1 378 PRO n 1 379 ILE n 1 380 GLU n 1 381 VAL n 1 382 CYS n 1 383 PRO n 1 384 ILE n 1 385 SER n 1 386 ASN n 1 387 GLN n 1 388 VAL n 1 389 LEU n 1 390 LYS n 1 391 LEU n 1 392 VAL n 1 393 SER n 1 394 ASP n 1 395 LEU n 1 396 ARG n 1 397 ASN n 1 398 HIS n 1 399 PRO n 1 400 VAL n 1 401 ALA n 1 402 THR n 1 403 LEU n 1 404 MET n 1 405 ALA n 1 406 THR n 1 407 GLY n 1 408 HIS n 1 409 PRO n 1 410 MET n 1 411 VAL n 1 412 ILE n 1 413 SER n 1 414 SER n 1 415 ASP n 1 416 ASP n 1 417 PRO n 1 418 ALA n 1 419 MET n 1 420 PHE n 1 421 GLY n 1 422 ALA n 1 423 LYS n 1 424 GLY n 1 425 LEU n 1 426 SER n 1 427 TYR n 1 428 ASP n 1 429 PHE n 1 430 TYR n 1 431 GLU n 1 432 VAL n 1 433 PHE n 1 434 MET n 1 435 GLY n 1 436 ILE n 1 437 GLY n 1 438 GLY n 1 439 MET n 1 440 LYS n 1 441 ALA n 1 442 ASP n 1 443 LEU n 1 444 ARG n 1 445 THR n 1 446 LEU n 1 447 LYS n 1 448 GLN n 1 449 LEU n 1 450 ALA n 1 451 MET n 1 452 ASN n 1 453 SER n 1 454 ILE n 1 455 LYS n 1 456 TYR n 1 457 SER n 1 458 THR n 1 459 LEU n 1 460 LEU n 1 461 GLU n 1 462 SER n 1 463 GLU n 1 464 LYS n 1 465 ASN n 1 466 THR n 1 467 PHE n 1 468 MET n 1 469 GLU n 1 470 ILE n 1 471 TRP n 1 472 LYS n 1 473 LYS n 1 474 ARG n 1 475 TRP n 1 476 ASP n 1 477 LYS n 1 478 PHE n 1 479 ILE n 1 480 ALA n 1 481 ASP n 1 482 VAL n 1 483 ALA n 1 484 THR n 1 485 LYS n 1 486 GLY n 1 487 SER n 1 488 LEU n 1 489 HIS n 1 490 HIS n 1 491 ILE n 1 492 LEU n 1 493 ASP n 1 494 ALA n 1 495 GLN n 1 496 LYS n 1 497 MET n 1 498 VAL n 1 499 TRP n 1 500 ASN n 1 501 HIS n 1 502 ARG n 1 503 HIS n 1 504 HIS n 1 505 HIS n 1 506 HIS n 1 507 HIS n 1 508 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'ADA2, CECR1, IDGFL' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name Drosophila _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7215 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'pRMHa3, pS2neo' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pRMHa3-ADA2 _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code CECR1_HUMAN _struct_ref.pdbx_db_accession Q9NZK5 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SIDETRAHLLLKEKMMRLGGRLVLNTKEELANERLMTLKIAEMKEAMRTLIFPPSMHFFQAKHLIERSQVFNILRMMPKG AALHLHDIGIVTMDWLVRNVTYRPHCHICFTPRGIMQFRFAHPTPRPSEKCSKWILLEDYRKRVQNVTEFDDSLLRNFTL VTQHPEVIYTNQNVVWSKFETIFFTISGLIHYAPVFRDYVFRSMQEFYEDNVLYMEIRARLLPVYELSGEHHDEEWSVKT YQEVAQKFVETHPEFIGIKIIYSDHRSKDVAVIAESIRMAMGLRIKFPTVVAGFDLVGHEDTGHSLHDYKEALMIPAKDG VKLPYFFHAGETDWQGTSIDRNILDALMLNTTRIGHGFALSKHPAVRTYSWKKDIPIEVCPISNQVLKLVSDLRNHPVAT LMATGHPMVISSDDPAMFGAKGLSYDFYEVFMGIGGMKADLRTLKQLAMNSIKYSTLLESEKNTFMEIWKKRWDKFIADV ATK ; _struct_ref.pdbx_align_begin 29 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3LGG A 3 ? 485 ? Q9NZK5 29 ? 511 ? 3 485 2 1 3LGG B 3 ? 485 ? Q9NZK5 29 ? 511 ? 3 485 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3LGG GLY A 1 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 1 1 1 3LGG GLY A 2 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 2 2 1 3LGG GLY A 486 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 486 3 1 3LGG SER A 487 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 487 4 1 3LGG LEU A 488 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 488 5 1 3LGG HIS A 489 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 489 6 1 3LGG HIS A 490 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 490 7 1 3LGG ILE A 491 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 491 8 1 3LGG LEU A 492 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 492 9 1 3LGG ASP A 493 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 493 10 1 3LGG ALA A 494 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 494 11 1 3LGG GLN A 495 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 495 12 1 3LGG LYS A 496 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 496 13 1 3LGG MET A 497 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 497 14 1 3LGG VAL A 498 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 498 15 1 3LGG TRP A 499 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 499 16 1 3LGG ASN A 500 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 500 17 1 3LGG HIS A 501 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 501 18 1 3LGG ARG A 502 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 502 19 1 3LGG HIS A 503 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 503 20 1 3LGG HIS A 504 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 504 21 1 3LGG HIS A 505 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 505 22 1 3LGG HIS A 506 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 506 23 1 3LGG HIS A 507 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 507 24 1 3LGG HIS A 508 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 508 25 2 3LGG GLY B 1 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 1 26 2 3LGG GLY B 2 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 2 27 2 3LGG GLY B 486 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 486 28 2 3LGG SER B 487 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 487 29 2 3LGG LEU B 488 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 488 30 2 3LGG HIS B 489 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 489 31 2 3LGG HIS B 490 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 490 32 2 3LGG ILE B 491 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 491 33 2 3LGG LEU B 492 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 492 34 2 3LGG ASP B 493 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 493 35 2 3LGG ALA B 494 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 494 36 2 3LGG GLN B 495 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 495 37 2 3LGG LYS B 496 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 496 38 2 3LGG MET B 497 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 497 39 2 3LGG VAL B 498 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 498 40 2 3LGG TRP B 499 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 499 41 2 3LGG ASN B 500 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 500 42 2 3LGG HIS B 501 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 501 43 2 3LGG ARG B 502 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 502 44 2 3LGG HIS B 503 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 503 45 2 3LGG HIS B 504 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 504 46 2 3LGG HIS B 505 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 505 47 2 3LGG HIS B 506 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 506 48 2 3LGG HIS B 507 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 507 49 2 3LGG HIS B 508 ? UNP Q9NZK5 ? ? 'EXPRESSION TAG' 508 50 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CFE non-polymer . '(8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol' Coformycin 'C11 H16 N4 O5' 284.269 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 3LGG _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number ? # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.87 _exptl_crystal.density_percent_sol 57.13 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.04 _exptl_crystal_grow.pdbx_details '40% MPD, 5% PEG 8000, 0.1M cacodylate, 2 mM coformycin, pH 6.04, VAPOR DIFFUSION, HANGING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range ? # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.pdbx_collection_date 2007-06-30 _diffrn_detector.details mirrors # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'channel-cut silicon monochromator' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.009 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'ESRF BEAMLINE ID29' _diffrn_source.pdbx_synchrotron_site ESRF _diffrn_source.pdbx_synchrotron_beamline ID29 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.009 # _reflns.entry_id 3LGG _reflns.observed_criterion_sigma_I ? _reflns.observed_criterion_sigma_F ? _reflns.d_resolution_low 73.52 _reflns.d_resolution_high 2.5 _reflns.number_obs 43967 _reflns.number_all ? _reflns.percent_possible_obs 96.8 _reflns.pdbx_Rmerge_I_obs 0.069 _reflns.pdbx_Rsym_value 0.069 _reflns.pdbx_netI_over_sigmaI 9.794 _reflns.B_iso_Wilson_estimate 40.899 _reflns.pdbx_redundancy 3.9 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _reflns_shell.d_res_high 2.5 _reflns_shell.d_res_low 2.64 _reflns_shell.percent_possible_all 95.8 _reflns_shell.Rmerge_I_obs 0.32 _reflns_shell.pdbx_Rsym_value 0.32 _reflns_shell.meanI_over_sigI_obs 3.1 _reflns_shell.pdbx_redundancy 3.9 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 6368 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id ? _reflns_shell.pdbx_ordinal 1 # _refine.entry_id 3LGG _refine.ls_number_reflns_obs 41746 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 66.82 _refine.ls_d_res_high 2.50 _refine.ls_percent_reflns_obs 96.84 _refine.ls_R_factor_obs 0.19414 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.19249 _refine.ls_R_factor_R_free 0.22483 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 2221 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.936 _refine.correlation_coeff_Fo_to_Fc_free 0.916 _refine.B_iso_mean 34.931 _refine.aniso_B[1][1] -0.10 _refine.aniso_B[2][2] 0.18 _refine.aniso_B[3][3] -0.48 _refine.aniso_B[1][2] -0.40 _refine.aniso_B[1][3] -0.12 _refine.aniso_B[2][3] -0.46 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct SAD _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.477 _refine.pdbx_overall_ESU_R_Free 0.257 _refine.overall_SU_ML 0.179 _refine.overall_SU_B 8.083 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 7855 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 126 _refine_hist.number_atoms_solvent 244 _refine_hist.number_atoms_total 8225 _refine_hist.d_res_high 2.50 _refine_hist.d_res_low 66.82 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.009 0.022 ? 8193 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.225 1.965 ? 11088 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 5.292 5.000 ? 962 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 33.397 23.065 ? 372 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 18.085 15.000 ? 1446 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 17.321 15.000 ? 56 'X-RAY DIFFRACTION' ? r_chiral_restr 0.079 0.200 ? 1229 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.004 0.021 ? 6120 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.474 1.500 ? 4814 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 0.965 2.000 ? 7824 'X-RAY DIFFRACTION' ? r_scbond_it 1.531 3.000 ? 3379 'X-RAY DIFFRACTION' ? r_scangle_it 2.724 4.500 ? 3264 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_restr_ncs.pdbx_refine_id _refine_ls_restr_ncs.pdbx_ens_id _refine_ls_restr_ncs.dom_id _refine_ls_restr_ncs.pdbx_type _refine_ls_restr_ncs.pdbx_auth_asym_id _refine_ls_restr_ncs.pdbx_number _refine_ls_restr_ncs.rms_dev_position _refine_ls_restr_ncs.weight_position _refine_ls_restr_ncs.pdbx_ordinal _refine_ls_restr_ncs.ncs_model_details _refine_ls_restr_ncs.rms_dev_B_iso _refine_ls_restr_ncs.weight_B_iso 'X-RAY DIFFRACTION' 1 1 'TIGHT POSITIONAL' A 480 0.020 0.050 1 ? ? ? 'X-RAY DIFFRACTION' 1 1 'MEDIUM POSITIONAL' A 507 0.040 0.500 2 ? ? ? 'X-RAY DIFFRACTION' 1 1 'TIGHT THERMAL' A 480 0.040 0.500 3 ? ? ? 'X-RAY DIFFRACTION' 1 1 'MEDIUM THERMAL' A 507 0.050 2.000 4 ? ? ? 'X-RAY DIFFRACTION' 2 1 'MEDIUM POSITIONAL' A 239 0.430 0.500 5 ? ? ? 'X-RAY DIFFRACTION' 2 1 'MEDIUM THERMAL' A 239 0.250 2.000 6 ? ? ? 'X-RAY DIFFRACTION' 3 1 'TIGHT POSITIONAL' A 1332 0.020 0.050 7 ? ? ? 'X-RAY DIFFRACTION' 3 1 'MEDIUM POSITIONAL' A 1360 0.060 0.500 8 ? ? ? 'X-RAY DIFFRACTION' 3 1 'TIGHT THERMAL' A 1332 0.040 0.500 9 ? ? ? 'X-RAY DIFFRACTION' 3 1 'MEDIUM THERMAL' A 1360 0.050 2.000 10 ? ? ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.500 _refine_ls_shell.d_res_low 2.565 _refine_ls_shell.number_reflns_R_work 3045 _refine_ls_shell.R_factor_R_work 0.261 _refine_ls_shell.percent_reflns_obs 96.31 _refine_ls_shell.R_factor_R_free 0.311 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 165 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _struct_ncs_dom.pdbx_ens_id _struct_ncs_dom.id _struct_ncs_dom.details 1 1 A 1 2 B 2 1 A 2 2 B 3 1 A 3 2 B # loop_ _struct_ncs_dom_lim.pdbx_ens_id _struct_ncs_dom_lim.dom_id _struct_ncs_dom_lim.pdbx_component_id _struct_ncs_dom_lim.pdbx_refine_code _struct_ncs_dom_lim.beg_auth_asym_id _struct_ncs_dom_lim.beg_auth_seq_id _struct_ncs_dom_lim.end_auth_asym_id _struct_ncs_dom_lim.end_auth_seq_id _struct_ncs_dom_lim.selection_details _struct_ncs_dom_lim.beg_label_asym_id _struct_ncs_dom_lim.beg_label_comp_id _struct_ncs_dom_lim.beg_label_seq_id _struct_ncs_dom_lim.beg_label_alt_id _struct_ncs_dom_lim.end_label_asym_id _struct_ncs_dom_lim.end_label_comp_id _struct_ncs_dom_lim.end_label_seq_id _struct_ncs_dom_lim.end_label_alt_id 1 1 1 2 A 4 A 123 ? . . . . . . . . 1 2 1 2 B 4 B 123 ? . . . . . . . . 2 1 1 4 A 124 A 151 ? . . . . . . . . 2 2 1 4 B 124 B 151 ? . . . . . . . . 3 1 1 2 A 152 A 484 ? . . . . . . . . 3 2 1 2 B 152 B 484 ? . . . . . . . . # loop_ _struct_ncs_ens.id _struct_ncs_ens.details 1 ? 2 ? 3 ? # _struct.entry_id 3LGG _struct.title ;Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2) complexed with transition state analogue, coformycin ; _struct.pdbx_descriptor 'Adenosine deaminase CECR1 (E.C.3.5.4.4)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3LGG _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'TIM barrel, dimerization and receptor binding domains, Glycoprotein, Hydrolase, Growth Factor, Secreted' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 3 ? G N N 4 ? H N N 2 ? I N N 2 ? J N N 2 ? K N N 3 ? L N N 4 ? M N N 5 ? N N N 5 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 3 ? ARG A 19 ? SER A 3 ARG A 19 1 ? 17 HELX_P HELX_P2 2 ASN A 27 ? LEU A 52 ? ASN A 27 LEU A 52 1 ? 26 HELX_P HELX_P3 3 PHE A 54 ? MET A 58 ? PHE A 54 MET A 58 5 ? 5 HELX_P HELX_P4 4 HIS A 59 ? GLU A 68 ? HIS A 59 GLU A 68 1 ? 10 HELX_P HELX_P5 5 SER A 70 ? MET A 79 ? SER A 70 MET A 79 1 ? 10 HELX_P HELX_P6 6 THR A 94 ? ASN A 101 ? THR A 94 ASN A 101 1 ? 8 HELX_P HELX_P7 7 LEU A 139 ? ARG A 143 ? LEU A 139 ARG A 143 1 ? 5 HELX_P HELX_P8 8 ASN A 148 ? ARG A 158 ? ASN A 148 ARG A 158 1 ? 11 HELX_P HELX_P9 9 HIS A 166 ? TYR A 171 ? HIS A 166 TYR A 171 1 ? 6 HELX_P HELX_P10 10 ASN A 173 ? HIS A 193 ? ASN A 173 HIS A 193 1 ? 21 HELX_P HELX_P11 11 TYR A 194 ? ASP A 212 ? TYR A 194 ASP A 212 1 ? 19 HELX_P HELX_P12 12 ASP A 235 ? THR A 253 ? ASP A 235 THR A 253 1 ? 19 HELX_P HELX_P13 13 ASP A 271 ? PHE A 289 ? ASP A 271 PHE A 289 1 ? 19 HELX_P HELX_P14 14 TYR A 311 ? MET A 316 ? TYR A 311 MET A 316 1 ? 6 HELX_P HELX_P15 15 MET A 316 ? ASP A 321 ? MET A 316 ASP A 321 1 ? 6 HELX_P HELX_P16 16 ARG A 343 ? LEU A 351 ? ARG A 343 LEU A 351 1 ? 9 HELX_P HELX_P17 17 ALA A 361 ? LYS A 364 ? ALA A 361 LYS A 364 5 ? 4 HELX_P HELX_P18 18 HIS A 365 ? LYS A 375 ? HIS A 365 LYS A 375 1 ? 11 HELX_P HELX_P19 19 CYS A 382 ? LEU A 389 ? CYS A 382 LEU A 389 1 ? 8 HELX_P HELX_P20 20 ASP A 394 ? HIS A 398 ? ASP A 394 HIS A 398 5 ? 5 HELX_P HELX_P21 21 PRO A 399 ? THR A 406 ? PRO A 399 THR A 406 1 ? 8 HELX_P HELX_P22 22 ASP A 416 ? PHE A 420 ? ASP A 416 PHE A 420 5 ? 5 HELX_P HELX_P23 23 LEU A 425 ? GLY A 435 ? LEU A 425 GLY A 435 1 ? 11 HELX_P HELX_P24 24 ASP A 442 ? TYR A 456 ? ASP A 442 TYR A 456 1 ? 15 HELX_P HELX_P25 25 LEU A 460 ? THR A 484 ? LEU A 460 THR A 484 1 ? 25 HELX_P HELX_P26 26 SER B 3 ? ARG B 19 ? SER B 3 ARG B 19 1 ? 17 HELX_P HELX_P27 27 ASN B 27 ? LEU B 52 ? ASN B 27 LEU B 52 1 ? 26 HELX_P HELX_P28 28 PHE B 54 ? MET B 58 ? PHE B 54 MET B 58 5 ? 5 HELX_P HELX_P29 29 HIS B 59 ? ARG B 69 ? HIS B 59 ARG B 69 1 ? 11 HELX_P HELX_P30 30 SER B 70 ? MET B 79 ? SER B 70 MET B 79 1 ? 10 HELX_P HELX_P31 31 THR B 94 ? ASN B 101 ? THR B 94 ASN B 101 1 ? 8 HELX_P HELX_P32 32 VAL B 102 ? ARG B 105 ? VAL B 102 ARG B 105 5 ? 4 HELX_P HELX_P33 33 LEU B 139 ? VAL B 146 ? LEU B 139 VAL B 146 1 ? 8 HELX_P HELX_P34 34 ASN B 148 ? ARG B 158 ? ASN B 148 ARG B 158 1 ? 11 HELX_P HELX_P35 35 HIS B 166 ? TYR B 171 ? HIS B 166 TYR B 171 1 ? 6 HELX_P HELX_P36 36 ASN B 173 ? HIS B 193 ? ASN B 173 HIS B 193 1 ? 21 HELX_P HELX_P37 37 TYR B 194 ? ASP B 212 ? TYR B 194 ASP B 212 1 ? 19 HELX_P HELX_P38 38 ASP B 235 ? HIS B 254 ? ASP B 235 HIS B 254 1 ? 20 HELX_P HELX_P39 39 ASP B 271 ? PHE B 289 ? ASP B 271 PHE B 289 1 ? 19 HELX_P HELX_P40 40 TYR B 311 ? MET B 316 ? TYR B 311 MET B 316 1 ? 6 HELX_P HELX_P41 41 MET B 316 ? ASP B 321 ? MET B 316 ASP B 321 1 ? 6 HELX_P HELX_P42 42 ARG B 343 ? LEU B 351 ? ARG B 343 LEU B 351 1 ? 9 HELX_P HELX_P43 43 ALA B 361 ? LYS B 364 ? ALA B 361 LYS B 364 5 ? 4 HELX_P HELX_P44 44 HIS B 365 ? LYS B 375 ? HIS B 365 LYS B 375 1 ? 11 HELX_P HELX_P45 45 CYS B 382 ? LEU B 389 ? CYS B 382 LEU B 389 1 ? 8 HELX_P HELX_P46 46 ASP B 394 ? HIS B 398 ? ASP B 394 HIS B 398 5 ? 5 HELX_P HELX_P47 47 PRO B 399 ? THR B 406 ? PRO B 399 THR B 406 1 ? 8 HELX_P HELX_P48 48 ASP B 416 ? PHE B 420 ? ASP B 416 PHE B 420 5 ? 5 HELX_P HELX_P49 49 LEU B 425 ? GLY B 435 ? LEU B 425 GLY B 435 1 ? 11 HELX_P HELX_P50 50 ASP B 442 ? TYR B 456 ? ASP B 442 TYR B 456 1 ? 15 HELX_P HELX_P51 51 LEU B 460 ? THR B 484 ? LEU B 460 THR B 484 1 ? 25 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 111 SG ? ? ? 1_555 A CYS 133 SG ? ? A CYS 111 A CYS 133 1_555 ? ? ? ? ? ? ? 2.039 ? disulf2 disulf ? ? B CYS 111 SG ? ? ? 1_555 B CYS 133 SG ? ? B CYS 111 B CYS 133 1_555 ? ? ? ? ? ? ? 2.024 ? covale1 covale ? ? A ASN 101 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 101 A NAG 509 1_555 ? ? ? ? ? ? ? 1.432 ? covale2 covale ? ? A ASN 159 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 159 A NAG 510 1_555 ? ? ? ? ? ? ? 1.434 ? covale3 covale ? ? B ASN 101 ND2 ? ? ? 1_555 H NAG . C1 ? ? B ASN 101 B NAG 509 1_555 ? ? ? ? ? ? ? 1.436 ? covale4 covale ? ? A ASN 352 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 352 A NAG 511 1_555 ? ? ? ? ? ? ? 1.447 ? covale5 covale ? ? B ASN 352 ND2 ? ? ? 1_555 J NAG . C1 ? ? B ASN 352 B NAG 511 1_555 ? ? ? ? ? ? ? 1.449 ? covale6 covale ? ? B ASN 159 ND2 ? ? ? 1_555 I NAG . C1 ? ? B ASN 159 B NAG 510 1_555 ? ? ? ? ? ? ? 1.464 ? metalc1 metalc ? ? F ZN . ZN ? ? ? 1_555 G CFE . O8 ? ? A ZN 512 A CFE 513 1_555 ? ? ? ? ? ? ? 1.854 ? metalc2 metalc ? ? K ZN . ZN ? ? ? 1_555 L CFE . O8 ? ? B ZN 512 B CFE 513 1_555 ? ? ? ? ? ? ? 1.915 ? metalc3 metalc ? ? B HIS 86 NE2 ? ? ? 1_555 K ZN . ZN ? ? B HIS 86 B ZN 512 1_555 ? ? ? ? ? ? ? 2.085 ? metalc4 metalc ? ? B HIS 88 NE2 ? ? ? 1_555 K ZN . ZN ? ? B HIS 88 B ZN 512 1_555 ? ? ? ? ? ? ? 2.171 ? metalc5 metalc ? ? A HIS 88 NE2 ? ? ? 1_555 F ZN . ZN ? ? A HIS 88 A ZN 512 1_555 ? ? ? ? ? ? ? 2.194 ? metalc6 metalc ? ? A HIS 86 NE2 ? ? ? 1_555 F ZN . ZN ? ? A HIS 86 A ZN 512 1_555 ? ? ? ? ? ? ? 2.223 ? metalc7 metalc ? ? B HIS 330 NE2 ? ? ? 1_555 K ZN . ZN ? ? B HIS 330 B ZN 512 1_555 ? ? ? ? ? ? ? 2.307 ? metalc8 metalc ? ? A HIS 330 NE2 ? ? ? 1_555 F ZN . ZN ? ? A HIS 330 A ZN 512 1_555 ? ? ? ? ? ? ? 2.339 ? metalc9 metalc ? ? A ASP 415 OD1 ? ? ? 1_555 F ZN . ZN ? ? A ASP 415 A ZN 512 1_555 ? ? ? ? ? ? ? 2.520 ? metalc10 metalc ? ? B ASP 415 OD1 ? ? ? 1_555 K ZN . ZN ? ? B ASP 415 B ZN 512 1_555 ? ? ? ? ? ? ? 2.552 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 HIS 124 A . ? HIS 124 A PRO 125 A ? PRO 125 A 1 1.50 2 HIS 124 B . ? HIS 124 B PRO 125 B ? PRO 125 B 1 -0.64 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 4 ? B ? 3 ? C ? 4 ? D ? 4 ? E ? 3 ? F ? 4 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel C 1 2 ? parallel C 2 3 ? parallel C 3 4 ? parallel D 1 2 ? parallel D 2 3 ? parallel D 3 4 ? parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel F 1 2 ? parallel F 2 3 ? parallel F 3 4 ? parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 GLY A 82 ? HIS A 88 ? GLY A 82 HIS A 88 A 2 VAL A 214 ? ALA A 221 ? VAL A 214 ALA A 221 A 3 GLY A 259 ? HIS A 267 ? GLY A 259 HIS A 267 A 4 VAL A 293 ? VAL A 299 ? VAL A 293 VAL A 299 B 1 MET A 118 ? PHE A 122 ? MET A 118 PHE A 122 B 2 CYS A 108 ? PHE A 112 ? CYS A 108 PHE A 112 B 3 ILE A 137 ? LEU A 138 ? ILE A 137 LEU A 138 C 1 HIS A 330 ? ALA A 331 ? HIS A 330 ALA A 331 C 2 ILE A 356 ? HIS A 358 ? ILE A 356 HIS A 358 C 3 ILE A 379 ? VAL A 381 ? ILE A 379 VAL A 381 C 4 MET A 410 ? ILE A 412 ? MET A 410 ILE A 412 D 1 GLY B 82 ? HIS B 88 ? GLY B 82 HIS B 88 D 2 VAL B 214 ? ALA B 221 ? VAL B 214 ALA B 221 D 3 GLY B 259 ? HIS B 267 ? GLY B 259 HIS B 267 D 4 VAL B 293 ? VAL B 299 ? VAL B 293 VAL B 299 E 1 MET B 118 ? PHE B 122 ? MET B 118 PHE B 122 E 2 CYS B 108 ? PHE B 112 ? CYS B 108 PHE B 112 E 3 ILE B 137 ? LEU B 138 ? ILE B 137 LEU B 138 F 1 HIS B 330 ? ALA B 331 ? HIS B 330 ALA B 331 F 2 ILE B 356 ? HIS B 358 ? ILE B 356 HIS B 358 F 3 ILE B 379 ? VAL B 381 ? ILE B 379 VAL B 381 F 4 MET B 410 ? ILE B 412 ? MET B 410 ILE B 412 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N LEU A 87 ? N LEU A 87 O ARG A 220 ? O ARG A 220 A 2 3 N ILE A 219 ? N ILE A 219 O ILE A 263 ? O ILE A 263 A 3 4 N ASP A 266 ? N ASP A 266 O VAL A 299 ? O VAL A 299 B 1 2 O ARG A 121 ? O ARG A 121 N HIS A 109 ? N HIS A 109 B 2 3 N ILE A 110 ? N ILE A 110 O ILE A 137 ? O ILE A 137 C 1 2 N ALA A 331 ? N ALA A 331 O GLY A 357 ? O GLY A 357 C 2 3 N ILE A 356 ? N ILE A 356 O GLU A 380 ? O GLU A 380 C 3 4 N VAL A 381 ? N VAL A 381 O VAL A 411 ? O VAL A 411 D 1 2 N LEU B 87 ? N LEU B 87 O ARG B 220 ? O ARG B 220 D 2 3 N ILE B 219 ? N ILE B 219 O ILE B 263 ? O ILE B 263 D 3 4 N ILE B 262 ? N ILE B 262 O ALA B 294 ? O ALA B 294 E 1 2 O ARG B 121 ? O ARG B 121 N HIS B 109 ? N HIS B 109 E 2 3 N ILE B 110 ? N ILE B 110 O ILE B 137 ? O ILE B 137 F 1 2 N ALA B 331 ? N ALA B 331 O GLY B 357 ? O GLY B 357 F 2 3 N ILE B 356 ? N ILE B 356 O GLU B 380 ? O GLU B 380 F 3 4 N VAL B 381 ? N VAL B 381 O VAL B 411 ? O VAL B 411 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 509' AC2 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 510' AC3 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 511' AC4 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE ZN A 512' AC5 Software ? ? ? ? 16 'BINDING SITE FOR RESIDUE CFE A 513' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG B 509' AC7 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 510' AC8 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG B 511' AC9 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE ZN B 512' BC1 Software ? ? ? ? 16 'BINDING SITE FOR RESIDUE CFE B 513' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 TRP A 97 ? TRP A 97 . ? 1_555 ? 2 AC1 5 ASN A 101 ? ASN A 101 . ? 1_555 ? 3 AC1 5 ARG A 105 ? ARG A 105 . ? 1_555 ? 4 AC1 5 ASP A 200 ? ASP A 200 . ? 1_555 ? 5 AC1 5 HOH M . ? HOH A 628 . ? 1_555 ? 6 AC2 4 SER A 155 ? SER A 155 . ? 1_555 ? 7 AC2 4 ARG A 158 ? ARG A 158 . ? 1_555 ? 8 AC2 4 ASN A 159 ? ASN A 159 . ? 1_555 ? 9 AC2 4 HOH M . ? HOH A 588 . ? 1_555 ? 10 AC3 4 ALA A 319 ? ALA A 319 . ? 1_555 ? 11 AC3 4 LEU A 351 ? LEU A 351 . ? 1_555 ? 12 AC3 4 ASN A 352 ? ASN A 352 . ? 1_555 ? 13 AC3 4 ILE B 4 ? ILE B 4 . ? 1_555 ? 14 AC4 6 HIS A 86 ? HIS A 86 . ? 1_555 ? 15 AC4 6 HIS A 88 ? HIS A 88 . ? 1_555 ? 16 AC4 6 HIS A 330 ? HIS A 330 . ? 1_555 ? 17 AC4 6 HIS A 358 ? HIS A 358 . ? 1_555 ? 18 AC4 6 ASP A 415 ? ASP A 415 . ? 1_555 ? 19 AC4 6 CFE G . ? CFE A 513 . ? 1_555 ? 20 AC5 16 HIS A 88 ? HIS A 88 . ? 1_555 ? 21 AC5 16 ASP A 89 ? ASP A 89 . ? 1_555 ? 22 AC5 16 TRP A 178 ? TRP A 178 . ? 1_555 ? 23 AC5 16 PHE A 181 ? PHE A 181 . ? 1_555 ? 24 AC5 16 GLU A 182 ? GLU A 182 . ? 1_555 ? 25 AC5 16 ARG A 222 ? ARG A 222 . ? 1_555 ? 26 AC5 16 HIS A 267 ? HIS A 267 . ? 1_555 ? 27 AC5 16 GLY A 300 ? GLY A 300 . ? 1_555 ? 28 AC5 16 HIS A 330 ? HIS A 330 . ? 1_555 ? 29 AC5 16 GLU A 333 ? GLU A 333 . ? 1_555 ? 30 AC5 16 HIS A 358 ? HIS A 358 . ? 1_555 ? 31 AC5 16 ASP A 415 ? ASP A 415 . ? 1_555 ? 32 AC5 16 ASP A 416 ? ASP A 416 . ? 1_555 ? 33 AC5 16 ZN F . ? ZN A 512 . ? 1_555 ? 34 AC5 16 HOH M . ? HOH A 541 . ? 1_555 ? 35 AC5 16 HOH M . ? HOH A 614 . ? 1_555 ? 36 AC6 3 TRP B 97 ? TRP B 97 . ? 1_555 ? 37 AC6 3 ASN B 101 ? ASN B 101 . ? 1_555 ? 38 AC6 3 ARG B 105 ? ARG B 105 . ? 1_555 ? 39 AC7 5 ARG B 158 ? ARG B 158 . ? 1_555 ? 40 AC7 5 ASN B 159 ? ASN B 159 . ? 1_555 ? 41 AC7 5 THR B 161 ? THR B 161 . ? 1_555 ? 42 AC7 5 LYS B 180 ? LYS B 180 . ? 1_555 ? 43 AC7 5 ILE B 184 ? ILE B 184 . ? 1_555 ? 44 AC8 2 ALA B 319 ? ALA B 319 . ? 1_555 ? 45 AC8 2 ASN B 352 ? ASN B 352 . ? 1_555 ? 46 AC9 6 HIS B 86 ? HIS B 86 . ? 1_555 ? 47 AC9 6 HIS B 88 ? HIS B 88 . ? 1_555 ? 48 AC9 6 HIS B 330 ? HIS B 330 . ? 1_555 ? 49 AC9 6 HIS B 358 ? HIS B 358 . ? 1_555 ? 50 AC9 6 ASP B 415 ? ASP B 415 . ? 1_555 ? 51 AC9 6 CFE L . ? CFE B 513 . ? 1_555 ? 52 BC1 16 HIS B 86 ? HIS B 86 . ? 1_555 ? 53 BC1 16 HIS B 88 ? HIS B 88 . ? 1_555 ? 54 BC1 16 ASP B 89 ? ASP B 89 . ? 1_555 ? 55 BC1 16 TRP B 178 ? TRP B 178 . ? 1_555 ? 56 BC1 16 PHE B 181 ? PHE B 181 . ? 1_555 ? 57 BC1 16 GLU B 182 ? GLU B 182 . ? 1_555 ? 58 BC1 16 ARG B 222 ? ARG B 222 . ? 1_555 ? 59 BC1 16 HIS B 267 ? HIS B 267 . ? 1_555 ? 60 BC1 16 GLY B 300 ? GLY B 300 . ? 1_555 ? 61 BC1 16 HIS B 330 ? HIS B 330 . ? 1_555 ? 62 BC1 16 GLU B 333 ? GLU B 333 . ? 1_555 ? 63 BC1 16 HIS B 358 ? HIS B 358 . ? 1_555 ? 64 BC1 16 ASP B 415 ? ASP B 415 . ? 1_555 ? 65 BC1 16 ASP B 416 ? ASP B 416 . ? 1_555 ? 66 BC1 16 ZN K . ? ZN B 512 . ? 1_555 ? 67 BC1 16 HOH N . ? HOH B 602 . ? 1_555 ? # _database_PDB_matrix.entry_id 3LGG _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3LGG _atom_sites.fract_transf_matrix[1][1] 0.015811 _atom_sites.fract_transf_matrix[1][2] 0.000422 _atom_sites.fract_transf_matrix[1][3] 0.001663 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.013705 _atom_sites.fract_transf_matrix[2][3] 0.006043 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.013620 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 3 ? -25.767 -25.179 6.187 1.00 54.69 ? 3 SER A N 1 ATOM 2 C CA . SER A 1 3 ? -24.445 -25.842 6.372 1.00 54.88 ? 3 SER A CA 1 ATOM 3 C C . SER A 1 3 ? -23.315 -25.097 5.655 1.00 54.93 ? 3 SER A C 1 ATOM 4 O O . SER A 1 3 ? -22.189 -25.040 6.154 1.00 54.90 ? 3 SER A O 1 ATOM 5 C CB . SER A 1 3 ? -24.501 -27.290 5.898 1.00 54.93 ? 3 SER A CB 1 ATOM 6 O OG . SER A 1 3 ? -23.254 -27.923 6.107 1.00 54.93 ? 3 SER A OG 1 ATOM 7 N N . ILE A 1 4 ? -23.613 -24.554 4.476 1.00 54.81 ? 4 ILE A N 1 ATOM 8 C CA . ILE A 1 4 ? -22.714 -23.603 3.830 1.00 54.61 ? 4 ILE A CA 1 ATOM 9 C C . ILE A 1 4 ? -22.819 -22.271 4.579 1.00 54.34 ? 4 ILE A C 1 ATOM 10 O O . ILE A 1 4 ? -21.814 -21.581 4.776 1.00 54.42 ? 4 ILE A O 1 ATOM 11 C CB . ILE A 1 4 ? -22.991 -23.458 2.298 1.00 54.71 ? 4 ILE A CB 1 ATOM 12 C CG1 . ILE A 1 4 ? -22.646 -24.764 1.571 1.00 54.67 ? 4 ILE A CG1 1 ATOM 13 C CG2 . ILE A 1 4 ? -22.179 -22.303 1.693 1.00 54.76 ? 4 ILE A CG2 1 ATOM 14 C CD1 . ILE A 1 4 ? -23.031 -24.796 0.105 1.00 54.76 ? 4 ILE A CD1 1 ATOM 15 N N . ASP A 1 5 ? -24.033 -21.939 5.021 1.00 53.96 ? 5 ASP A N 1 ATOM 16 C CA . ASP A 1 5 ? -24.271 -20.788 5.901 1.00 53.64 ? 5 ASP A CA 1 ATOM 17 C C . ASP A 1 5 ? -23.436 -20.862 7.168 1.00 52.86 ? 5 ASP A C 1 ATOM 18 O O . ASP A 1 5 ? -22.974 -19.844 7.687 1.00 52.70 ? 5 ASP A O 1 ATOM 19 C CB . ASP A 1 5 ? -25.742 -20.712 6.295 1.00 53.96 ? 5 ASP A CB 1 ATOM 20 C CG . ASP A 1 5 ? -26.614 -20.232 5.170 1.00 55.22 ? 5 ASP A CG 1 ATOM 21 O OD1 . ASP A 1 5 ? -27.165 -19.118 5.288 1.00 56.45 ? 5 ASP A OD1 1 ATOM 22 O OD2 . ASP A 1 5 ? -26.741 -20.964 4.165 1.00 56.80 ? 5 ASP A OD2 1 ATOM 23 N N . GLU A 1 6 ? -23.259 -22.084 7.656 1.00 51.87 ? 6 GLU A N 1 ATOM 24 C CA . GLU A 1 6 ? -22.501 -22.333 8.862 1.00 51.00 ? 6 GLU A CA 1 ATOM 25 C C . GLU A 1 6 ? -21.009 -22.178 8.634 1.00 49.59 ? 6 GLU A C 1 ATOM 26 O O . GLU A 1 6 ? -20.305 -21.673 9.501 1.00 49.54 ? 6 GLU A O 1 ATOM 27 C CB . GLU A 1 6 ? -22.823 -23.723 9.406 1.00 51.48 ? 6 GLU A CB 1 ATOM 28 C CG . GLU A 1 6 ? -24.160 -23.787 10.140 1.00 53.42 ? 6 GLU A CG 1 ATOM 29 C CD . GLU A 1 6 ? -24.661 -25.207 10.346 1.00 56.04 ? 6 GLU A CD 1 ATOM 30 O OE1 . GLU A 1 6 ? -23.839 -26.155 10.304 1.00 56.93 ? 6 GLU A OE1 1 ATOM 31 O OE2 . GLU A 1 6 ? -25.885 -25.372 10.550 1.00 56.91 ? 6 GLU A OE2 1 ATOM 32 N N . THR A 1 7 ? -20.533 -22.617 7.470 1.00 47.94 ? 7 THR A N 1 ATOM 33 C CA . THR A 1 7 ? -19.132 -22.431 7.079 1.00 46.11 ? 7 THR A CA 1 ATOM 34 C C . THR A 1 7 ? -18.809 -20.943 6.977 1.00 44.83 ? 7 THR A C 1 ATOM 35 O O . THR A 1 7 ? -17.764 -20.494 7.449 1.00 44.61 ? 7 THR A O 1 ATOM 36 C CB . THR A 1 7 ? -18.823 -23.106 5.730 1.00 46.20 ? 7 THR A CB 1 ATOM 37 O OG1 . THR A 1 7 ? -19.320 -24.450 5.739 1.00 46.39 ? 7 THR A OG1 1 ATOM 38 C CG2 . THR A 1 7 ? -17.315 -23.127 5.456 1.00 46.01 ? 7 THR A CG2 1 ATOM 39 N N . ARG A 1 8 ? -19.728 -20.193 6.372 1.00 43.10 ? 8 ARG A N 1 ATOM 40 C CA . ARG A 1 8 ? -19.598 -18.757 6.216 1.00 41.41 ? 8 ARG A CA 1 ATOM 41 C C . ARG A 1 8 ? -19.532 -18.061 7.575 1.00 40.89 ? 8 ARG A C 1 ATOM 42 O O . ARG A 1 8 ? -18.648 -17.231 7.804 1.00 40.85 ? 8 ARG A O 1 ATOM 43 C CB . ARG A 1 8 ? -20.764 -18.217 5.387 1.00 41.07 ? 8 ARG A CB 1 ATOM 44 C CG . ARG A 1 8 ? -20.641 -16.764 4.995 1.00 39.07 ? 8 ARG A CG 1 ATOM 45 C CD . ARG A 1 8 ? -21.957 -16.263 4.494 1.00 35.98 ? 8 ARG A CD 1 ATOM 46 N NE . ARG A 1 8 ? -21.842 -14.979 3.817 1.00 34.88 ? 8 ARG A NE 1 ATOM 47 C CZ . ARG A 1 8 ? -21.954 -13.792 4.410 1.00 35.56 ? 8 ARG A CZ 1 ATOM 48 N NH1 . ARG A 1 8 ? -22.175 -13.706 5.719 1.00 36.36 ? 8 ARG A NH1 1 ATOM 49 N NH2 . ARG A 1 8 ? -21.839 -12.682 3.686 1.00 34.59 ? 8 ARG A NH2 1 ATOM 50 N N . ALA A 1 9 ? -20.460 -18.411 8.467 1.00 40.01 ? 9 ALA A N 1 ATOM 51 C CA . ALA A 1 9 ? -20.542 -17.806 9.801 1.00 39.26 ? 9 ALA A CA 1 ATOM 52 C C . ALA A 1 9 ? -19.330 -18.163 10.652 1.00 38.60 ? 9 ALA A C 1 ATOM 53 O O . ALA A 1 9 ? -18.899 -17.380 11.498 1.00 38.17 ? 9 ALA A O 1 ATOM 54 C CB . ALA A 1 9 ? -21.831 -18.227 10.506 1.00 39.15 ? 9 ALA A CB 1 ATOM 55 N N . HIS A 1 10 ? -18.786 -19.353 10.411 1.00 38.12 ? 10 HIS A N 1 ATOM 56 C CA . HIS A 1 10 ? -17.628 -19.847 11.144 1.00 37.68 ? 10 HIS A CA 1 ATOM 57 C C . HIS A 1 10 ? -16.363 -19.064 10.781 1.00 36.94 ? 10 HIS A C 1 ATOM 58 O O . HIS A 1 10 ? -15.570 -18.710 11.656 1.00 36.86 ? 10 HIS A O 1 ATOM 59 C CB . HIS A 1 10 ? -17.444 -21.349 10.903 1.00 37.84 ? 10 HIS A CB 1 ATOM 60 C CG . HIS A 1 10 ? -16.208 -21.910 11.529 1.00 39.68 ? 10 HIS A CG 1 ATOM 61 N ND1 . HIS A 1 10 ? -16.102 -22.153 12.883 1.00 41.70 ? 10 HIS A ND1 1 ATOM 62 C CD2 . HIS A 1 10 ? -15.016 -22.260 10.989 1.00 41.16 ? 10 HIS A CD2 1 ATOM 63 C CE1 . HIS A 1 10 ? -14.897 -22.628 13.150 1.00 42.22 ? 10 HIS A CE1 1 ATOM 64 N NE2 . HIS A 1 10 ? -14.219 -22.706 12.018 1.00 42.14 ? 10 HIS A NE2 1 ATOM 65 N N . LEU A 1 11 ? -16.197 -18.786 9.488 1.00 36.18 ? 11 LEU A N 1 ATOM 66 C CA . LEU A 1 11 ? -15.060 -18.020 8.979 1.00 35.17 ? 11 LEU A CA 1 ATOM 67 C C . LEU A 1 11 ? -15.091 -16.575 9.475 1.00 35.07 ? 11 LEU A C 1 ATOM 68 O O . LEU A 1 11 ? -14.053 -16.016 9.843 1.00 35.09 ? 11 LEU A O 1 ATOM 69 C CB . LEU A 1 11 ? -15.005 -18.087 7.449 1.00 34.64 ? 11 LEU A CB 1 ATOM 70 C CG . LEU A 1 11 ? -14.634 -19.466 6.892 1.00 33.87 ? 11 LEU A CG 1 ATOM 71 C CD1 . LEU A 1 11 ? -15.044 -19.630 5.436 1.00 33.17 ? 11 LEU A CD1 1 ATOM 72 C CD2 . LEU A 1 11 ? -13.153 -19.748 7.054 1.00 32.70 ? 11 LEU A CD2 1 ATOM 73 N N . LEU A 1 12 ? -16.283 -15.983 9.508 1.00 34.71 ? 12 LEU A N 1 ATOM 74 C CA . LEU A 1 12 ? -16.448 -14.638 10.049 1.00 34.72 ? 12 LEU A CA 1 ATOM 75 C C . LEU A 1 12 ? -16.154 -14.566 11.551 1.00 35.01 ? 12 LEU A C 1 ATOM 76 O O . LEU A 1 12 ? -15.555 -13.601 12.016 1.00 35.08 ? 12 LEU A O 1 ATOM 77 C CB . LEU A 1 12 ? -17.845 -14.078 9.738 1.00 34.19 ? 12 LEU A CB 1 ATOM 78 C CG . LEU A 1 12 ? -18.101 -13.639 8.293 1.00 33.56 ? 12 LEU A CG 1 ATOM 79 C CD1 . LEU A 1 12 ? -19.577 -13.282 8.076 1.00 31.73 ? 12 LEU A CD1 1 ATOM 80 C CD2 . LEU A 1 12 ? -17.173 -12.486 7.865 1.00 30.70 ? 12 LEU A CD2 1 ATOM 81 N N . LEU A 1 13 ? -16.573 -15.588 12.299 1.00 35.54 ? 13 LEU A N 1 ATOM 82 C CA . LEU A 1 13 ? -16.332 -15.631 13.738 1.00 35.89 ? 13 LEU A CA 1 ATOM 83 C C . LEU A 1 13 ? -14.856 -15.859 14.029 1.00 35.94 ? 13 LEU A C 1 ATOM 84 O O . LEU A 1 13 ? -14.309 -15.268 14.957 1.00 35.80 ? 13 LEU A O 1 ATOM 85 C CB . LEU A 1 13 ? -17.183 -16.704 14.428 1.00 36.00 ? 13 LEU A CB 1 ATOM 86 C CG . LEU A 1 13 ? -16.997 -16.753 15.955 1.00 36.66 ? 13 LEU A CG 1 ATOM 87 C CD1 . LEU A 1 13 ? -17.867 -15.712 16.666 1.00 36.51 ? 13 LEU A CD1 1 ATOM 88 C CD2 . LEU A 1 13 ? -17.248 -18.146 16.510 1.00 36.82 ? 13 LEU A CD2 1 ATOM 89 N N . LYS A 1 14 ? -14.218 -16.710 13.229 1.00 36.24 ? 14 LYS A N 1 ATOM 90 C CA . LYS A 1 14 ? -12.780 -16.947 13.358 1.00 36.71 ? 14 LYS A CA 1 ATOM 91 C C . LYS A 1 14 ? -11.996 -15.643 13.170 1.00 36.36 ? 14 LYS A C 1 ATOM 92 O O . LYS A 1 14 ? -11.115 -15.325 13.972 1.00 36.45 ? 14 LYS A O 1 ATOM 93 C CB . LYS A 1 14 ? -12.302 -18.017 12.375 1.00 36.97 ? 14 LYS A CB 1 ATOM 94 C CG . LYS A 1 14 ? -11.023 -18.692 12.816 1.00 39.48 ? 14 LYS A CG 1 ATOM 95 C CD . LYS A 1 14 ? -10.165 -19.119 11.635 1.00 43.91 ? 14 LYS A CD 1 ATOM 96 C CE . LYS A 1 14 ? -10.139 -20.623 11.408 1.00 46.41 ? 14 LYS A CE 1 ATOM 97 N NZ . LYS A 1 14 ? -9.192 -20.945 10.290 1.00 48.24 ? 14 LYS A NZ 1 ATOM 98 N N . GLU A 1 15 ? -12.341 -14.880 12.136 1.00 35.89 ? 15 GLU A N 1 ATOM 99 C CA . GLU A 1 15 ? -11.694 -13.593 11.892 1.00 35.81 ? 15 GLU A CA 1 ATOM 100 C C . GLU A 1 15 ? -11.995 -12.549 12.963 1.00 35.80 ? 15 GLU A C 1 ATOM 101 O O . GLU A 1 15 ? -11.135 -11.720 13.298 1.00 35.66 ? 15 GLU A O 1 ATOM 102 C CB . GLU A 1 15 ? -12.030 -13.073 10.496 1.00 35.79 ? 15 GLU A CB 1 ATOM 103 C CG . GLU A 1 15 ? -11.090 -13.642 9.446 1.00 36.24 ? 15 GLU A CG 1 ATOM 104 C CD . GLU A 1 15 ? -11.473 -13.303 8.025 1.00 37.17 ? 15 GLU A CD 1 ATOM 105 O OE1 . GLU A 1 15 ? -12.302 -12.389 7.819 1.00 37.69 ? 15 GLU A OE1 1 ATOM 106 O OE2 . GLU A 1 15 ? -10.933 -13.962 7.109 1.00 37.04 ? 15 GLU A OE2 1 ATOM 107 N N . LYS A 1 16 ? -13.209 -12.603 13.507 1.00 35.71 ? 16 LYS A N 1 ATOM 108 C CA . LYS A 1 16 ? -13.590 -11.764 14.640 1.00 35.83 ? 16 LYS A CA 1 ATOM 109 C C . LYS A 1 16 ? -12.708 -12.075 15.849 1.00 35.97 ? 16 LYS A C 1 ATOM 110 O O . LYS A 1 16 ? -12.303 -11.170 16.585 1.00 35.67 ? 16 LYS A O 1 ATOM 111 C CB . LYS A 1 16 ? -15.073 -11.967 14.982 1.00 35.73 ? 16 LYS A CB 1 ATOM 112 C CG . LYS A 1 16 ? -15.659 -10.982 16.001 1.00 35.25 ? 16 LYS A CG 1 ATOM 113 C CD . LYS A 1 16 ? -17.121 -11.336 16.276 1.00 36.15 ? 16 LYS A CD 1 ATOM 114 C CE . LYS A 1 16 ? -17.779 -10.460 17.337 1.00 36.43 ? 16 LYS A CE 1 ATOM 115 N NZ . LYS A 1 16 ? -17.275 -9.059 17.388 1.00 37.27 ? 16 LYS A NZ 1 ATOM 116 N N . MET A 1 17 ? -12.402 -13.359 16.027 1.00 36.49 ? 17 MET A N 1 ATOM 117 C CA . MET A 1 17 ? -11.649 -13.827 17.190 1.00 37.28 ? 17 MET A CA 1 ATOM 118 C C . MET A 1 17 ? -10.143 -13.602 17.091 1.00 37.27 ? 17 MET A C 1 ATOM 119 O O . MET A 1 17 ? -9.511 -13.286 18.099 1.00 37.16 ? 17 MET A O 1 ATOM 120 C CB . MET A 1 17 ? -11.939 -15.306 17.492 1.00 37.55 ? 17 MET A CB 1 ATOM 121 C CG . MET A 1 17 ? -13.355 -15.614 18.001 1.00 39.27 ? 17 MET A CG 1 ATOM 122 S SD . MET A 1 17 ? -13.918 -14.614 19.414 1.00 43.98 ? 17 MET A SD 1 ATOM 123 C CE . MET A 1 17 ? -15.045 -13.453 18.635 1.00 41.27 ? 17 MET A CE 1 ATOM 124 N N . MET A 1 18 ? -9.565 -13.760 15.900 1.00 37.36 ? 18 MET A N 1 ATOM 125 C CA . MET A 1 18 ? -8.114 -13.608 15.774 1.00 37.60 ? 18 MET A CA 1 ATOM 126 C C . MET A 1 18 ? -7.600 -12.181 15.522 1.00 37.40 ? 18 MET A C 1 ATOM 127 O O . MET A 1 18 ? -6.409 -11.922 15.689 1.00 37.58 ? 18 MET A O 1 ATOM 128 C CB . MET A 1 18 ? -7.479 -14.647 14.833 1.00 37.88 ? 18 MET A CB 1 ATOM 129 C CG . MET A 1 18 ? -7.909 -14.627 13.380 1.00 39.90 ? 18 MET A CG 1 ATOM 130 S SD . MET A 1 18 ? -6.868 -15.740 12.381 1.00 44.15 ? 18 MET A SD 1 ATOM 131 C CE . MET A 1 18 ? -7.956 -17.101 12.074 1.00 43.68 ? 18 MET A CE 1 ATOM 132 N N . ARG A 1 19 ? -8.475 -11.245 15.170 1.00 37.18 ? 19 ARG A N 1 ATOM 133 C CA . ARG A 1 19 ? -8.021 -9.857 15.035 1.00 37.17 ? 19 ARG A CA 1 ATOM 134 C C . ARG A 1 19 ? -7.677 -9.269 16.402 1.00 37.25 ? 19 ARG A C 1 ATOM 135 O O . ARG A 1 19 ? -8.097 -9.790 17.445 1.00 37.37 ? 19 ARG A O 1 ATOM 136 C CB . ARG A 1 19 ? -9.010 -8.971 14.267 1.00 36.97 ? 19 ARG A CB 1 ATOM 137 C CG . ARG A 1 19 ? -10.230 -8.516 15.039 1.00 37.06 ? 19 ARG A CG 1 ATOM 138 C CD . ARG A 1 19 ? -10.996 -7.449 14.255 1.00 37.71 ? 19 ARG A CD 1 ATOM 139 N NE . ARG A 1 19 ? -11.566 -7.961 13.004 1.00 39.45 ? 19 ARG A NE 1 ATOM 140 C CZ . ARG A 1 19 ? -12.813 -8.419 12.861 1.00 39.84 ? 19 ARG A CZ 1 ATOM 141 N NH1 . ARG A 1 19 ? -13.656 -8.436 13.893 1.00 39.72 ? 19 ARG A NH1 1 ATOM 142 N NH2 . ARG A 1 19 ? -13.220 -8.858 11.679 1.00 37.98 ? 19 ARG A NH2 1 ATOM 143 N N . LEU A 1 20 ? -6.904 -8.190 16.377 1.00 37.03 ? 20 LEU A N 1 ATOM 144 C CA . LEU A 1 20 ? -6.333 -7.607 17.571 1.00 36.82 ? 20 LEU A CA 1 ATOM 145 C C . LEU A 1 20 ? -7.420 -7.232 18.565 1.00 36.76 ? 20 LEU A C 1 ATOM 146 O O . LEU A 1 20 ? -8.330 -6.460 18.247 1.00 36.61 ? 20 LEU A O 1 ATOM 147 C CB . LEU A 1 20 ? -5.472 -6.400 17.189 1.00 36.95 ? 20 LEU A CB 1 ATOM 148 C CG . LEU A 1 20 ? -4.560 -5.790 18.248 1.00 37.15 ? 20 LEU A CG 1 ATOM 149 C CD1 . LEU A 1 20 ? -3.161 -5.522 17.708 1.00 36.84 ? 20 LEU A CD1 1 ATOM 150 C CD2 . LEU A 1 20 ? -5.194 -4.517 18.765 1.00 37.79 ? 20 LEU A CD2 1 ATOM 151 N N . GLY A 1 21 ? -7.320 -7.808 19.762 1.00 36.72 ? 21 GLY A N 1 ATOM 152 C CA . GLY A 1 21 ? -8.273 -7.564 20.844 1.00 36.84 ? 21 GLY A CA 1 ATOM 153 C C . GLY A 1 21 ? -9.552 -8.384 20.781 1.00 36.98 ? 21 GLY A C 1 ATOM 154 O O . GLY A 1 21 ? -10.410 -8.267 21.656 1.00 36.96 ? 21 GLY A O 1 ATOM 155 N N . GLY A 1 22 ? -9.669 -9.224 19.756 1.00 37.10 ? 22 GLY A N 1 ATOM 156 C CA . GLY A 1 22 ? -10.897 -9.963 19.478 1.00 37.62 ? 22 GLY A CA 1 ATOM 157 C C . GLY A 1 22 ? -11.387 -10.897 20.575 1.00 37.89 ? 22 GLY A C 1 ATOM 158 O O . GLY A 1 22 ? -12.565 -11.269 20.600 1.00 37.78 ? 22 GLY A O 1 ATOM 159 N N . ARG A 1 23 ? -10.496 -11.270 21.488 1.00 38.22 ? 23 ARG A N 1 ATOM 160 C CA . ARG A 1 23 ? -10.864 -12.181 22.572 1.00 38.74 ? 23 ARG A CA 1 ATOM 161 C C . ARG A 1 23 ? -11.042 -11.515 23.935 1.00 38.21 ? 23 ARG A C 1 ATOM 162 O O . ARG A 1 23 ? -11.358 -12.183 24.919 1.00 38.48 ? 23 ARG A O 1 ATOM 163 C CB . ARG A 1 23 ? -9.887 -13.350 22.647 1.00 39.17 ? 23 ARG A CB 1 ATOM 164 C CG . ARG A 1 23 ? -10.036 -14.230 21.452 1.00 41.98 ? 23 ARG A CG 1 ATOM 165 C CD . ARG A 1 23 ? -9.247 -15.498 21.510 1.00 47.19 ? 23 ARG A CD 1 ATOM 166 N NE . ARG A 1 23 ? -9.701 -16.337 20.407 1.00 52.74 ? 23 ARG A NE 1 ATOM 167 C CZ . ARG A 1 23 ? -9.254 -17.557 20.134 1.00 55.98 ? 23 ARG A CZ 1 ATOM 168 N NH1 . ARG A 1 23 ? -8.311 -18.115 20.883 1.00 57.68 ? 23 ARG A NH1 1 ATOM 169 N NH2 . ARG A 1 23 ? -9.756 -18.221 19.099 1.00 57.44 ? 23 ARG A NH2 1 ATOM 170 N N . LEU A 1 24 ? -10.854 -10.199 23.981 1.00 37.55 ? 24 LEU A N 1 ATOM 171 C CA . LEU A 1 24 ? -11.158 -9.430 25.177 1.00 36.97 ? 24 LEU A CA 1 ATOM 172 C C . LEU A 1 24 ? -12.646 -9.493 25.460 1.00 36.88 ? 24 LEU A C 1 ATOM 173 O O . LEU A 1 24 ? -13.473 -9.306 24.558 1.00 36.83 ? 24 LEU A O 1 ATOM 174 C CB . LEU A 1 24 ? -10.708 -7.971 25.041 1.00 36.61 ? 24 LEU A CB 1 ATOM 175 C CG . LEU A 1 24 ? -9.210 -7.666 24.944 1.00 36.19 ? 24 LEU A CG 1 ATOM 176 C CD1 . LEU A 1 24 ? -8.976 -6.160 24.938 1.00 35.61 ? 24 LEU A CD1 1 ATOM 177 C CD2 . LEU A 1 24 ? -8.401 -8.337 26.064 1.00 34.83 ? 24 LEU A CD2 1 ATOM 178 N N . VAL A 1 25 ? -12.978 -9.778 26.716 1.00 36.83 ? 25 VAL A N 1 ATOM 179 C CA . VAL A 1 25 ? -14.365 -9.806 27.163 1.00 36.60 ? 25 VAL A CA 1 ATOM 180 C C . VAL A 1 25 ? -14.767 -8.420 27.652 1.00 36.59 ? 25 VAL A C 1 ATOM 181 O O . VAL A 1 25 ? -14.141 -7.865 28.549 1.00 36.67 ? 25 VAL A O 1 ATOM 182 C CB . VAL A 1 25 ? -14.605 -10.882 28.264 1.00 36.49 ? 25 VAL A CB 1 ATOM 183 C CG1 . VAL A 1 25 ? -16.029 -10.808 28.805 1.00 35.92 ? 25 VAL A CG1 1 ATOM 184 C CG2 . VAL A 1 25 ? -14.330 -12.268 27.715 1.00 36.00 ? 25 VAL A CG2 1 ATOM 185 N N . LEU A 1 26 ? -15.805 -7.870 27.032 1.00 36.70 ? 26 LEU A N 1 ATOM 186 C CA . LEU A 1 26 ? -16.377 -6.590 27.427 1.00 37.04 ? 26 LEU A CA 1 ATOM 187 C C . LEU A 1 26 ? -17.485 -6.753 28.482 1.00 37.49 ? 26 LEU A C 1 ATOM 188 O O . LEU A 1 26 ? -18.281 -7.689 28.411 1.00 37.72 ? 26 LEU A O 1 ATOM 189 C CB . LEU A 1 26 ? -16.945 -5.897 26.190 1.00 36.72 ? 26 LEU A CB 1 ATOM 190 C CG . LEU A 1 26 ? -16.213 -4.714 25.549 1.00 36.32 ? 26 LEU A CG 1 ATOM 191 C CD1 . LEU A 1 26 ? -14.696 -4.842 25.576 1.00 34.78 ? 26 LEU A CD1 1 ATOM 192 C CD2 . LEU A 1 26 ? -16.733 -4.473 24.134 1.00 35.23 ? 26 LEU A CD2 1 ATOM 193 N N . ASN A 1 27 ? -17.534 -5.850 29.458 1.00 37.70 ? 27 ASN A N 1 ATOM 194 C CA . ASN A 1 27 ? -18.672 -5.795 30.373 1.00 38.01 ? 27 ASN A CA 1 ATOM 195 C C . ASN A 1 27 ? -19.808 -4.988 29.746 1.00 38.44 ? 27 ASN A C 1 ATOM 196 O O . ASN A 1 27 ? -19.623 -4.363 28.703 1.00 38.69 ? 27 ASN A O 1 ATOM 197 C CB . ASN A 1 27 ? -18.267 -5.244 31.750 1.00 37.78 ? 27 ASN A CB 1 ATOM 198 C CG . ASN A 1 27 ? -17.905 -3.771 31.722 1.00 37.32 ? 27 ASN A CG 1 ATOM 199 O OD1 . ASN A 1 27 ? -18.533 -2.967 31.036 1.00 36.79 ? 27 ASN A OD1 1 ATOM 200 N ND2 . ASN A 1 27 ? -16.895 -3.408 32.488 1.00 36.83 ? 27 ASN A ND2 1 ATOM 201 N N . THR A 1 28 ? -20.972 -4.985 30.386 1.00 38.79 ? 28 THR A N 1 ATOM 202 C CA . THR A 1 28 ? -22.185 -4.439 29.763 1.00 38.95 ? 28 THR A CA 1 ATOM 203 C C . THR A 1 28 ? -22.088 -2.932 29.531 1.00 38.90 ? 28 THR A C 1 ATOM 204 O O . THR A 1 28 ? -22.681 -2.397 28.596 1.00 38.87 ? 28 THR A O 1 ATOM 205 C CB . THR A 1 28 ? -23.484 -4.804 30.560 1.00 39.11 ? 28 THR A CB 1 ATOM 206 O OG1 . THR A 1 28 ? -23.832 -3.742 31.454 1.00 39.66 ? 28 THR A OG1 1 ATOM 207 C CG2 . THR A 1 28 ? -23.317 -6.111 31.345 1.00 38.47 ? 28 THR A CG2 1 ATOM 208 N N . LYS A 1 29 ? -21.325 -2.265 30.389 1.00 39.12 ? 29 LYS A N 1 ATOM 209 C CA . LYS A 1 29 ? -21.042 -0.844 30.261 1.00 39.62 ? 29 LYS A CA 1 ATOM 210 C C . LYS A 1 29 ? -20.189 -0.585 29.011 1.00 39.28 ? 29 LYS A C 1 ATOM 211 O O . LYS A 1 29 ? -20.480 0.321 28.226 1.00 39.04 ? 29 LYS A O 1 ATOM 212 C CB . LYS A 1 29 ? -20.296 -0.371 31.509 1.00 40.01 ? 29 LYS A CB 1 ATOM 213 C CG . LYS A 1 29 ? -20.591 1.045 31.949 1.00 42.50 ? 29 LYS A CG 1 ATOM 214 C CD . LYS A 1 29 ? -21.644 1.050 33.035 1.00 47.24 ? 29 LYS A CD 1 ATOM 215 C CE . LYS A 1 29 ? -21.508 2.290 33.914 1.00 50.34 ? 29 LYS A CE 1 ATOM 216 N NZ . LYS A 1 29 ? -22.663 2.422 34.845 1.00 52.27 ? 29 LYS A NZ 1 ATOM 217 N N . GLU A 1 30 ? -19.142 -1.394 28.841 1.00 38.88 ? 30 GLU A N 1 ATOM 218 C CA . GLU A 1 30 ? -18.253 -1.321 27.683 1.00 38.71 ? 30 GLU A CA 1 ATOM 219 C C . GLU A 1 30 ? -18.956 -1.693 26.378 1.00 38.87 ? 30 GLU A C 1 ATOM 220 O O . GLU A 1 30 ? -18.689 -1.087 25.334 1.00 38.71 ? 30 GLU A O 1 ATOM 221 C CB . GLU A 1 30 ? -17.041 -2.222 27.876 1.00 38.53 ? 30 GLU A CB 1 ATOM 222 C CG . GLU A 1 30 ? -16.073 -1.766 28.943 1.00 38.08 ? 30 GLU A CG 1 ATOM 223 C CD . GLU A 1 30 ? -15.105 -2.862 29.330 1.00 38.07 ? 30 GLU A CD 1 ATOM 224 O OE1 . GLU A 1 30 ? -15.543 -4.020 29.487 1.00 38.04 ? 30 GLU A OE1 1 ATOM 225 O OE2 . GLU A 1 30 ? -13.902 -2.571 29.479 1.00 38.09 ? 30 GLU A OE2 1 ATOM 226 N N . GLU A 1 31 ? -19.839 -2.693 26.441 1.00 38.82 ? 31 GLU A N 1 ATOM 227 C CA . GLU A 1 31 ? -20.666 -3.072 25.291 1.00 39.07 ? 31 GLU A CA 1 ATOM 228 C C . GLU A 1 31 ? -21.521 -1.895 24.828 1.00 38.65 ? 31 GLU A C 1 ATOM 229 O O . GLU A 1 31 ? -21.713 -1.692 23.628 1.00 38.62 ? 31 GLU A O 1 ATOM 230 C CB . GLU A 1 31 ? -21.562 -4.270 25.618 1.00 39.19 ? 31 GLU A CB 1 ATOM 231 C CG . GLU A 1 31 ? -20.835 -5.611 25.659 1.00 41.43 ? 31 GLU A CG 1 ATOM 232 C CD . GLU A 1 31 ? -20.567 -6.217 24.277 1.00 44.74 ? 31 GLU A CD 1 ATOM 233 O OE1 . GLU A 1 31 ? -20.504 -5.474 23.264 1.00 46.36 ? 31 GLU A OE1 1 ATOM 234 O OE2 . GLU A 1 31 ? -20.415 -7.457 24.205 1.00 45.55 ? 31 GLU A OE2 1 ATOM 235 N N . LEU A 1 32 ? -22.012 -1.121 25.791 1.00 38.34 ? 32 LEU A N 1 ATOM 236 C CA . LEU A 1 32 ? -22.838 0.046 25.510 1.00 38.22 ? 32 LEU A CA 1 ATOM 237 C C . LEU A 1 32 ? -22.027 1.180 24.876 1.00 37.64 ? 32 LEU A C 1 ATOM 238 O O . LEU A 1 32 ? -22.494 1.835 23.939 1.00 37.61 ? 32 LEU A O 1 ATOM 239 C CB . LEU A 1 32 ? -23.536 0.527 26.790 1.00 38.33 ? 32 LEU A CB 1 ATOM 240 C CG . LEU A 1 32 ? -24.931 1.152 26.683 1.00 39.38 ? 32 LEU A CG 1 ATOM 241 C CD1 . LEU A 1 32 ? -24.910 2.539 26.053 1.00 40.70 ? 32 LEU A CD1 1 ATOM 242 C CD2 . LEU A 1 32 ? -25.879 0.232 25.922 1.00 40.48 ? 32 LEU A CD2 1 ATOM 243 N N . ALA A 1 33 ? -20.823 1.402 25.395 1.00 37.05 ? 33 ALA A N 1 ATOM 244 C CA . ALA A 1 33 ? -19.898 2.389 24.839 1.00 36.66 ? 33 ALA A CA 1 ATOM 245 C C . ALA A 1 33 ? -19.452 1.977 23.433 1.00 36.37 ? 33 ALA A C 1 ATOM 246 O O . ALA A 1 33 ? -19.399 2.805 22.522 1.00 36.26 ? 33 ALA A O 1 ATOM 247 C CB . ALA A 1 33 ? -18.696 2.567 25.755 1.00 36.64 ? 33 ALA A CB 1 ATOM 248 N N . ASN A 1 34 ? -19.153 0.692 23.262 1.00 35.89 ? 34 ASN A N 1 ATOM 249 C CA . ASN A 1 34 ? -18.801 0.158 21.961 1.00 35.59 ? 34 ASN A CA 1 ATOM 250 C C . ASN A 1 34 ? -19.906 0.374 20.934 1.00 35.80 ? 34 ASN A C 1 ATOM 251 O O . ASN A 1 34 ? -19.630 0.762 19.807 1.00 35.90 ? 34 ASN A O 1 ATOM 252 C CB . ASN A 1 34 ? -18.445 -1.324 22.060 1.00 35.36 ? 34 ASN A CB 1 ATOM 253 C CG . ASN A 1 34 ? -18.028 -1.914 20.723 1.00 34.42 ? 34 ASN A CG 1 ATOM 254 O OD1 . ASN A 1 34 ? -18.714 -2.772 20.179 1.00 34.26 ? 34 ASN A OD1 1 ATOM 255 N ND2 . ASN A 1 34 ? -16.916 -1.438 20.181 1.00 31.45 ? 34 ASN A ND2 1 ATOM 256 N N . GLU A 1 35 ? -21.150 0.125 21.333 1.00 36.15 ? 35 GLU A N 1 ATOM 257 C CA . GLU A 1 35 ? -22.309 0.289 20.451 1.00 36.60 ? 35 GLU A CA 1 ATOM 258 C C . GLU A 1 35 ? -22.472 1.733 19.973 1.00 36.01 ? 35 GLU A C 1 ATOM 259 O O . GLU A 1 35 ? -22.793 1.975 18.809 1.00 35.91 ? 35 GLU A O 1 ATOM 260 C CB . GLU A 1 35 ? -23.584 -0.179 21.152 1.00 36.90 ? 35 GLU A CB 1 ATOM 261 C CG . GLU A 1 35 ? -24.745 -0.457 20.208 1.00 40.03 ? 35 GLU A CG 1 ATOM 262 C CD . GLU A 1 35 ? -26.075 -0.587 20.939 1.00 43.87 ? 35 GLU A CD 1 ATOM 263 O OE1 . GLU A 1 35 ? -26.588 0.443 21.433 1.00 45.33 ? 35 GLU A OE1 1 ATOM 264 O OE2 . GLU A 1 35 ? -26.611 -1.716 21.018 1.00 45.40 ? 35 GLU A OE2 1 ATOM 265 N N . ARG A 1 36 ? -22.242 2.685 20.872 1.00 35.57 ? 36 ARG A N 1 ATOM 266 C CA . ARG A 1 36 ? -22.345 4.102 20.521 1.00 35.44 ? 36 ARG A CA 1 ATOM 267 C C . ARG A 1 36 ? -21.122 4.546 19.706 1.00 34.51 ? 36 ARG A C 1 ATOM 268 O O . ARG A 1 36 ? -21.256 5.284 18.724 1.00 34.49 ? 36 ARG A O 1 ATOM 269 C CB . ARG A 1 36 ? -22.582 4.974 21.768 1.00 35.73 ? 36 ARG A CB 1 ATOM 270 C CG . ARG A 1 36 ? -23.829 4.548 22.568 1.00 37.93 ? 36 ARG A CG 1 ATOM 271 C CD . ARG A 1 36 ? -24.252 5.569 23.605 1.00 42.11 ? 36 ARG A CD 1 ATOM 272 N NE . ARG A 1 36 ? -24.923 6.711 22.982 1.00 45.97 ? 36 ARG A NE 1 ATOM 273 C CZ . ARG A 1 36 ? -25.003 7.931 23.512 1.00 47.50 ? 36 ARG A CZ 1 ATOM 274 N NH1 . ARG A 1 36 ? -24.453 8.192 24.694 1.00 47.68 ? 36 ARG A NH1 1 ATOM 275 N NH2 . ARG A 1 36 ? -25.631 8.896 22.847 1.00 48.02 ? 36 ARG A NH2 1 ATOM 276 N N . LEU A 1 37 ? -19.946 4.063 20.093 1.00 33.46 ? 37 LEU A N 1 ATOM 277 C CA . LEU A 1 37 ? -18.730 4.273 19.310 1.00 32.60 ? 37 LEU A CA 1 ATOM 278 C C . LEU A 1 37 ? -18.836 3.726 17.871 1.00 32.07 ? 37 LEU A C 1 ATOM 279 O O . LEU A 1 37 ? -18.562 4.464 16.920 1.00 31.73 ? 37 LEU A O 1 ATOM 280 C CB . LEU A 1 37 ? -17.498 3.712 20.038 1.00 32.37 ? 37 LEU A CB 1 ATOM 281 C CG . LEU A 1 37 ? -16.147 3.717 19.304 1.00 32.03 ? 37 LEU A CG 1 ATOM 282 C CD1 . LEU A 1 37 ? -15.612 5.133 19.023 1.00 30.32 ? 37 LEU A CD1 1 ATOM 283 C CD2 . LEU A 1 37 ? -15.131 2.905 20.090 1.00 31.40 ? 37 LEU A CD2 1 ATOM 284 N N . MET A 1 38 ? -19.252 2.465 17.719 1.00 31.47 ? 38 MET A N 1 ATOM 285 C CA . MET A 1 38 ? -19.382 1.835 16.390 1.00 31.41 ? 38 MET A CA 1 ATOM 286 C C . MET A 1 38 ? -20.441 2.478 15.485 1.00 30.96 ? 38 MET A C 1 ATOM 287 O O . MET A 1 38 ? -20.255 2.560 14.276 1.00 30.83 ? 38 MET A O 1 ATOM 288 C CB . MET A 1 38 ? -19.619 0.324 16.496 1.00 31.46 ? 38 MET A CB 1 ATOM 289 C CG . MET A 1 38 ? -18.421 -0.490 17.002 1.00 32.52 ? 38 MET A CG 1 ATOM 290 S SD . MET A 1 38 ? -16.896 -0.356 16.024 1.00 33.30 ? 38 MET A SD 1 ATOM 291 C CE . MET A 1 38 ? -16.211 1.118 16.736 1.00 35.66 ? 38 MET A CE 1 ATOM 292 N N . THR A 1 39 ? -21.543 2.934 16.073 1.00 30.85 ? 39 THR A N 1 ATOM 293 C CA . THR A 1 39 ? -22.557 3.698 15.336 1.00 30.47 ? 39 THR A CA 1 ATOM 294 C C . THR A 1 39 ? -21.940 4.943 14.713 1.00 30.44 ? 39 THR A C 1 ATOM 295 O O . THR A 1 39 ? -22.192 5.238 13.544 1.00 30.64 ? 39 THR A O 1 ATOM 296 C CB . THR A 1 39 ? -23.738 4.119 16.242 1.00 30.38 ? 39 THR A CB 1 ATOM 297 O OG1 . THR A 1 39 ? -24.452 2.958 16.654 1.00 30.34 ? 39 THR A OG1 1 ATOM 298 C CG2 . THR A 1 39 ? -24.695 5.047 15.506 1.00 29.80 ? 39 THR A CG2 1 ATOM 299 N N . LEU A 1 40 ? -21.136 5.668 15.493 1.00 30.16 ? 40 LEU A N 1 ATOM 300 C CA . LEU A 1 40 ? -20.501 6.891 14.999 1.00 30.13 ? 40 LEU A CA 1 ATOM 301 C C . LEU A 1 40 ? -19.446 6.588 13.923 1.00 29.79 ? 40 LEU A C 1 ATOM 302 O O . LEU A 1 40 ? -19.313 7.330 12.947 1.00 29.60 ? 40 LEU A O 1 ATOM 303 C CB . LEU A 1 40 ? -19.912 7.701 16.156 1.00 30.19 ? 40 LEU A CB 1 ATOM 304 C CG . LEU A 1 40 ? -20.933 8.259 17.160 1.00 30.73 ? 40 LEU A CG 1 ATOM 305 C CD1 . LEU A 1 40 ? -20.267 8.612 18.483 1.00 30.57 ? 40 LEU A CD1 1 ATOM 306 C CD2 . LEU A 1 40 ? -21.700 9.457 16.604 1.00 30.46 ? 40 LEU A CD2 1 ATOM 307 N N . LYS A 1 41 ? -18.727 5.479 14.104 1.00 29.48 ? 41 LYS A N 1 ATOM 308 C CA . LYS A 1 41 ? -17.713 5.023 13.159 1.00 29.17 ? 41 LYS A CA 1 ATOM 309 C C . LYS A 1 41 ? -18.350 4.603 11.833 1.00 29.39 ? 41 LYS A C 1 ATOM 310 O O . LYS A 1 41 ? -17.956 5.086 10.778 1.00 29.58 ? 41 LYS A O 1 ATOM 311 C CB . LYS A 1 41 ? -16.895 3.877 13.762 1.00 28.87 ? 41 LYS A CB 1 ATOM 312 C CG . LYS A 1 41 ? -15.894 3.266 12.799 1.00 28.19 ? 41 LYS A CG 1 ATOM 313 C CD . LYS A 1 41 ? -15.027 2.224 13.457 1.00 26.11 ? 41 LYS A CD 1 ATOM 314 C CE . LYS A 1 41 ? -14.129 1.570 12.451 1.00 25.51 ? 41 LYS A CE 1 ATOM 315 N NZ . LYS A 1 41 ? -12.964 0.954 13.118 1.00 27.12 ? 41 LYS A NZ 1 ATOM 316 N N . ILE A 1 42 ? -19.334 3.715 11.894 1.00 29.53 ? 42 ILE A N 1 ATOM 317 C CA . ILE A 1 42 ? -20.040 3.252 10.701 1.00 29.97 ? 42 ILE A CA 1 ATOM 318 C C . ILE A 1 42 ? -20.656 4.395 9.867 1.00 30.65 ? 42 ILE A C 1 ATOM 319 O O . ILE A 1 42 ? -20.487 4.431 8.645 1.00 31.15 ? 42 ILE A O 1 ATOM 320 C CB . ILE A 1 42 ? -21.091 2.172 11.068 1.00 29.93 ? 42 ILE A CB 1 ATOM 321 C CG1 . ILE A 1 42 ? -20.379 0.849 11.380 1.00 29.19 ? 42 ILE A CG1 1 ATOM 322 C CG2 . ILE A 1 42 ? -22.132 1.993 9.950 1.00 29.68 ? 42 ILE A CG2 1 ATOM 323 C CD1 . ILE A 1 42 ? -21.151 -0.082 12.269 1.00 28.02 ? 42 ILE A CD1 1 ATOM 324 N N . ALA A 1 43 ? -21.356 5.320 10.524 1.00 31.04 ? 43 ALA A N 1 ATOM 325 C CA . ALA A 1 43 ? -21.932 6.490 9.863 1.00 31.64 ? 43 ALA A CA 1 ATOM 326 C C . ALA A 1 43 ? -20.866 7.326 9.142 1.00 32.22 ? 43 ALA A C 1 ATOM 327 O O . ALA A 1 43 ? -21.085 7.819 8.036 1.00 32.13 ? 43 ALA A O 1 ATOM 328 C CB . ALA A 1 43 ? -22.685 7.353 10.871 1.00 31.25 ? 43 ALA A CB 1 ATOM 329 N N . GLU A 1 44 ? -19.713 7.479 9.780 1.00 33.10 ? 44 GLU A N 1 ATOM 330 C CA . GLU A 1 44 ? -18.633 8.271 9.222 1.00 34.17 ? 44 GLU A CA 1 ATOM 331 C C . GLU A 1 44 ? -18.052 7.567 7.994 1.00 34.64 ? 44 GLU A C 1 ATOM 332 O O . GLU A 1 44 ? -17.747 8.203 6.984 1.00 34.54 ? 44 GLU A O 1 ATOM 333 C CB . GLU A 1 44 ? -17.560 8.486 10.278 1.00 34.13 ? 44 GLU A CB 1 ATOM 334 C CG . GLU A 1 44 ? -17.285 9.926 10.578 1.00 35.52 ? 44 GLU A CG 1 ATOM 335 C CD . GLU A 1 44 ? -16.383 10.096 11.783 1.00 37.28 ? 44 GLU A CD 1 ATOM 336 O OE1 . GLU A 1 44 ? -16.917 10.259 12.906 1.00 37.07 ? 44 GLU A OE1 1 ATOM 337 O OE2 . GLU A 1 44 ? -15.142 10.053 11.603 1.00 38.39 ? 44 GLU A OE2 1 ATOM 338 N N . MET A 1 45 ? -17.933 6.248 8.081 1.00 35.37 ? 45 MET A N 1 ATOM 339 C CA . MET A 1 45 ? -17.439 5.457 6.966 1.00 36.63 ? 45 MET A CA 1 ATOM 340 C C . MET A 1 45 ? -18.417 5.359 5.802 1.00 36.55 ? 45 MET A C 1 ATOM 341 O O . MET A 1 45 ? -17.990 5.371 4.649 1.00 36.32 ? 45 MET A O 1 ATOM 342 C CB . MET A 1 45 ? -16.965 4.077 7.427 1.00 37.21 ? 45 MET A CB 1 ATOM 343 C CG . MET A 1 45 ? -15.549 4.134 7.980 1.00 39.85 ? 45 MET A CG 1 ATOM 344 S SD . MET A 1 45 ? -14.883 2.553 8.493 1.00 46.79 ? 45 MET A SD 1 ATOM 345 C CE . MET A 1 45 ? -14.138 1.995 6.957 1.00 45.28 ? 45 MET A CE 1 ATOM 346 N N . LYS A 1 46 ? -19.711 5.255 6.105 1.00 36.71 ? 46 LYS A N 1 ATOM 347 C CA . LYS A 1 46 ? -20.760 5.306 5.080 1.00 37.00 ? 46 LYS A CA 1 ATOM 348 C C . LYS A 1 46 ? -20.643 6.569 4.242 1.00 36.67 ? 46 LYS A C 1 ATOM 349 O O . LYS A 1 46 ? -20.645 6.512 3.004 1.00 36.73 ? 46 LYS A O 1 ATOM 350 C CB . LYS A 1 46 ? -22.156 5.215 5.708 1.00 37.33 ? 46 LYS A CB 1 ATOM 351 C CG . LYS A 1 46 ? -22.855 3.866 5.525 1.00 39.45 ? 46 LYS A CG 1 ATOM 352 C CD . LYS A 1 46 ? -21.947 2.685 5.889 1.00 42.08 ? 46 LYS A CD 1 ATOM 353 C CE . LYS A 1 46 ? -22.161 1.498 4.951 1.00 43.38 ? 46 LYS A CE 1 ATOM 354 N NZ . LYS A 1 46 ? -22.667 0.292 5.660 1.00 44.20 ? 46 LYS A NZ 1 ATOM 355 N N . GLU A 1 47 ? -20.510 7.702 4.927 1.00 35.98 ? 47 GLU A N 1 ATOM 356 C CA . GLU A 1 47 ? -20.385 8.996 4.272 1.00 35.67 ? 47 GLU A CA 1 ATOM 357 C C . GLU A 1 47 ? -19.112 9.104 3.414 1.00 35.23 ? 47 GLU A C 1 ATOM 358 O O . GLU A 1 47 ? -19.154 9.651 2.308 1.00 35.22 ? 47 GLU A O 1 ATOM 359 C CB . GLU A 1 47 ? -20.475 10.118 5.319 1.00 35.73 ? 47 GLU A CB 1 ATOM 360 C CG . GLU A 1 47 ? -20.331 11.540 4.779 1.00 36.67 ? 47 GLU A CG 1 ATOM 361 C CD . GLU A 1 47 ? -21.458 11.978 3.843 1.00 37.98 ? 47 GLU A CD 1 ATOM 362 O OE1 . GLU A 1 47 ? -22.410 11.208 3.582 1.00 37.52 ? 47 GLU A OE1 1 ATOM 363 O OE2 . GLU A 1 47 ? -21.375 13.121 3.357 1.00 40.02 ? 47 GLU A OE2 1 ATOM 364 N N . ALA A 1 48 ? -17.998 8.573 3.920 1.00 34.78 ? 48 ALA A N 1 ATOM 365 C CA . ALA A 1 48 ? -16.724 8.554 3.185 1.00 34.40 ? 48 ALA A CA 1 ATOM 366 C C . ALA A 1 48 ? -16.774 7.615 1.976 1.00 34.31 ? 48 ALA A C 1 ATOM 367 O O . ALA A 1 48 ? -16.119 7.861 0.965 1.00 34.07 ? 48 ALA A O 1 ATOM 368 C CB . ALA A 1 48 ? -15.572 8.184 4.107 1.00 34.21 ? 48 ALA A CB 1 ATOM 369 N N . MET A 1 49 ? -17.562 6.546 2.081 1.00 34.33 ? 49 MET A N 1 ATOM 370 C CA . MET A 1 49 ? -17.807 5.656 0.947 1.00 34.25 ? 49 MET A CA 1 ATOM 371 C C . MET A 1 49 ? -18.663 6.348 -0.113 1.00 34.43 ? 49 MET A C 1 ATOM 372 O O . MET A 1 49 ? -18.512 6.089 -1.304 1.00 34.72 ? 49 MET A O 1 ATOM 373 C CB . MET A 1 49 ? -18.450 4.343 1.405 1.00 34.06 ? 49 MET A CB 1 ATOM 374 C CG . MET A 1 49 ? -17.483 3.428 2.128 1.00 34.08 ? 49 MET A CG 1 ATOM 375 S SD . MET A 1 49 ? -18.257 2.133 3.100 1.00 34.81 ? 49 MET A SD 1 ATOM 376 C CE . MET A 1 49 ? -18.193 0.761 1.961 1.00 34.43 ? 49 MET A CE 1 ATOM 377 N N . ARG A 1 50 ? -19.549 7.238 0.323 1.00 34.63 ? 50 ARG A N 1 ATOM 378 C CA . ARG A 1 50 ? -20.368 8.010 -0.603 1.00 34.66 ? 50 ARG A CA 1 ATOM 379 C C . ARG A 1 50 ? -19.541 9.064 -1.348 1.00 34.59 ? 50 ARG A C 1 ATOM 380 O O . ARG A 1 50 ? -19.566 9.108 -2.576 1.00 34.68 ? 50 ARG A O 1 ATOM 381 C CB . ARG A 1 50 ? -21.539 8.664 0.132 1.00 34.69 ? 50 ARG A CB 1 ATOM 382 C CG . ARG A 1 50 ? -22.518 9.401 -0.772 1.00 35.57 ? 50 ARG A CG 1 ATOM 383 C CD . ARG A 1 50 ? -23.710 9.960 0.017 1.00 37.36 ? 50 ARG A CD 1 ATOM 384 N NE . ARG A 1 50 ? -23.371 11.137 0.826 1.00 38.96 ? 50 ARG A NE 1 ATOM 385 C CZ . ARG A 1 50 ? -23.273 12.376 0.344 1.00 39.60 ? 50 ARG A CZ 1 ATOM 386 N NH1 . ARG A 1 50 ? -23.477 12.606 -0.950 1.00 39.77 ? 50 ARG A NH1 1 ATOM 387 N NH2 . ARG A 1 50 ? -22.964 13.389 1.150 1.00 38.35 ? 50 ARG A NH2 1 ATOM 388 N N . THR A 1 51 ? -18.812 9.896 -0.599 1.00 34.17 ? 51 THR A N 1 ATOM 389 C CA . THR A 1 51 ? -18.117 11.060 -1.159 1.00 33.47 ? 51 THR A CA 1 ATOM 390 C C . THR A 1 51 ? -16.679 10.776 -1.571 1.00 32.85 ? 51 THR A C 1 ATOM 391 O O . THR A 1 51 ? -16.092 11.544 -2.322 1.00 32.92 ? 51 THR A O 1 ATOM 392 C CB . THR A 1 51 ? -18.095 12.259 -0.168 1.00 33.78 ? 51 THR A CB 1 ATOM 393 O OG1 . THR A 1 51 ? -17.291 11.936 0.978 1.00 33.50 ? 51 THR A OG1 1 ATOM 394 C CG2 . THR A 1 51 ? -19.509 12.647 0.267 1.00 33.37 ? 51 THR A CG2 1 ATOM 395 N N . LEU A 1 52 ? -16.123 9.673 -1.074 1.00 32.12 ? 52 LEU A N 1 ATOM 396 C CA . LEU A 1 52 ? -14.686 9.351 -1.190 1.00 31.03 ? 52 LEU A CA 1 ATOM 397 C C . LEU A 1 52 ? -13.770 10.325 -0.452 1.00 30.55 ? 52 LEU A C 1 ATOM 398 O O . LEU A 1 52 ? -12.554 10.267 -0.599 1.00 30.95 ? 52 LEU A O 1 ATOM 399 C CB . LEU A 1 52 ? -14.238 9.145 -2.645 1.00 31.07 ? 52 LEU A CB 1 ATOM 400 C CG . LEU A 1 52 ? -14.804 7.934 -3.408 1.00 30.63 ? 52 LEU A CG 1 ATOM 401 C CD1 . LEU A 1 52 ? -13.981 7.681 -4.658 1.00 30.17 ? 52 LEU A CD1 1 ATOM 402 C CD2 . LEU A 1 52 ? -14.863 6.674 -2.543 1.00 30.14 ? 52 LEU A CD2 1 ATOM 403 N N . ILE A 1 53 ? -14.354 11.206 0.355 1.00 29.72 ? 53 ILE A N 1 ATOM 404 C CA . ILE A 1 53 ? -13.579 12.022 1.286 1.00 28.53 ? 53 ILE A CA 1 ATOM 405 C C . ILE A 1 53 ? -13.349 11.207 2.565 1.00 27.24 ? 53 ILE A C 1 ATOM 406 O O . ILE A 1 53 ? -14.161 11.234 3.493 1.00 27.10 ? 53 ILE A O 1 ATOM 407 C CB . ILE A 1 53 ? -14.246 13.397 1.548 1.00 28.88 ? 53 ILE A CB 1 ATOM 408 C CG1 . ILE A 1 53 ? -14.157 14.269 0.288 1.00 29.39 ? 53 ILE A CG1 1 ATOM 409 C CG2 . ILE A 1 53 ? -13.590 14.125 2.724 1.00 28.88 ? 53 ILE A CG2 1 ATOM 410 C CD1 . ILE A 1 53 ? -15.195 15.361 0.220 1.00 29.19 ? 53 ILE A CD1 1 ATOM 411 N N . PHE A 1 54 ? -12.244 10.458 2.573 1.00 25.35 ? 54 PHE A N 1 ATOM 412 C CA . PHE A 1 54 ? -11.880 9.574 3.684 1.00 23.59 ? 54 PHE A CA 1 ATOM 413 C C . PHE A 1 54 ? -10.484 9.890 4.199 1.00 22.77 ? 54 PHE A C 1 ATOM 414 O O . PHE A 1 54 ? -9.502 9.535 3.553 1.00 22.92 ? 54 PHE A O 1 ATOM 415 C CB . PHE A 1 54 ? -11.966 8.111 3.238 1.00 23.12 ? 54 PHE A CB 1 ATOM 416 C CG . PHE A 1 54 ? -11.718 7.122 4.338 1.00 21.40 ? 54 PHE A CG 1 ATOM 417 C CD1 . PHE A 1 54 ? -12.522 7.107 5.477 1.00 19.22 ? 54 PHE A CD1 1 ATOM 418 C CD2 . PHE A 1 54 ? -10.702 6.185 4.224 1.00 19.05 ? 54 PHE A CD2 1 ATOM 419 C CE1 . PHE A 1 54 ? -12.303 6.188 6.498 1.00 18.68 ? 54 PHE A CE1 1 ATOM 420 C CE2 . PHE A 1 54 ? -10.476 5.263 5.240 1.00 18.35 ? 54 PHE A CE2 1 ATOM 421 C CZ . PHE A 1 54 ? -11.280 5.257 6.378 1.00 18.10 ? 54 PHE A CZ 1 ATOM 422 N N . PRO A 1 55 ? -10.390 10.555 5.368 1.00 22.06 ? 55 PRO A N 1 ATOM 423 C CA . PRO A 1 55 ? -9.103 11.097 5.844 1.00 21.56 ? 55 PRO A CA 1 ATOM 424 C C . PRO A 1 55 ? -7.877 10.166 5.794 1.00 21.28 ? 55 PRO A C 1 ATOM 425 O O . PRO A 1 55 ? -6.848 10.608 5.310 1.00 21.48 ? 55 PRO A O 1 ATOM 426 C CB . PRO A 1 55 ? -9.419 11.559 7.272 1.00 21.58 ? 55 PRO A CB 1 ATOM 427 C CG . PRO A 1 55 ? -10.882 11.868 7.233 1.00 21.14 ? 55 PRO A CG 1 ATOM 428 C CD . PRO A 1 55 ? -11.483 10.838 6.320 1.00 21.54 ? 55 PRO A CD 1 ATOM 429 N N . PRO A 1 56 ? -7.973 8.892 6.258 1.00 21.26 ? 56 PRO A N 1 ATOM 430 C CA . PRO A 1 56 ? -6.755 8.044 6.194 1.00 21.36 ? 56 PRO A CA 1 ATOM 431 C C . PRO A 1 56 ? -6.214 7.814 4.786 1.00 21.53 ? 56 PRO A C 1 ATOM 432 O O . PRO A 1 56 ? -5.017 7.555 4.617 1.00 21.23 ? 56 PRO A O 1 ATOM 433 C CB . PRO A 1 56 ? -7.211 6.711 6.808 1.00 21.24 ? 56 PRO A CB 1 ATOM 434 C CG . PRO A 1 56 ? -8.353 7.082 7.697 1.00 21.19 ? 56 PRO A CG 1 ATOM 435 C CD . PRO A 1 56 ? -9.066 8.197 6.967 1.00 20.93 ? 56 PRO A CD 1 ATOM 436 N N . SER A 1 57 ? -7.090 7.929 3.791 1.00 21.83 ? 57 SER A N 1 ATOM 437 C CA . SER A 1 57 ? -6.702 7.786 2.397 1.00 22.53 ? 57 SER A CA 1 ATOM 438 C C . SER A 1 57 ? -6.111 9.070 1.799 1.00 22.74 ? 57 SER A C 1 ATOM 439 O O . SER A 1 57 ? -5.534 9.045 0.718 1.00 23.02 ? 57 SER A O 1 ATOM 440 C CB . SER A 1 57 ? -7.889 7.299 1.565 1.00 22.72 ? 57 SER A CB 1 ATOM 441 O OG . SER A 1 57 ? -8.917 8.276 1.530 1.00 23.79 ? 57 SER A OG 1 ATOM 442 N N . MET A 1 58 ? -6.247 10.189 2.500 1.00 23.09 ? 58 MET A N 1 ATOM 443 C CA . MET A 1 58 ? -5.654 11.441 2.050 1.00 23.67 ? 58 MET A CA 1 ATOM 444 C C . MET A 1 58 ? -4.350 11.663 2.786 1.00 23.71 ? 58 MET A C 1 ATOM 445 O O . MET A 1 58 ? -4.110 11.047 3.829 1.00 23.81 ? 58 MET A O 1 ATOM 446 C CB . MET A 1 58 ? -6.567 12.630 2.339 1.00 23.90 ? 58 MET A CB 1 ATOM 447 C CG . MET A 1 58 ? -7.984 12.516 1.823 1.00 25.81 ? 58 MET A CG 1 ATOM 448 S SD . MET A 1 58 ? -8.955 13.938 2.386 1.00 31.17 ? 58 MET A SD 1 ATOM 449 C CE . MET A 1 58 ? -10.458 13.100 2.757 1.00 30.79 ? 58 MET A CE 1 ATOM 450 N N . HIS A 1 59 ? -3.515 12.550 2.251 1.00 23.52 ? 59 HIS A N 1 ATOM 451 C CA . HIS A 1 59 ? -2.322 12.974 2.958 1.00 23.71 ? 59 HIS A CA 1 ATOM 452 C C . HIS A 1 59 ? -2.720 13.690 4.248 1.00 23.94 ? 59 HIS A C 1 ATOM 453 O O . HIS A 1 59 ? -3.603 14.555 4.231 1.00 23.89 ? 59 HIS A O 1 ATOM 454 C CB . HIS A 1 59 ? -1.479 13.897 2.093 1.00 23.09 ? 59 HIS A CB 1 ATOM 455 C CG . HIS A 1 59 ? -0.082 14.056 2.588 1.00 22.89 ? 59 HIS A CG 1 ATOM 456 N ND1 . HIS A 1 59 ? 0.221 14.687 3.778 1.00 22.13 ? 59 HIS A ND1 1 ATOM 457 C CD2 . HIS A 1 59 ? 1.099 13.663 2.056 1.00 22.12 ? 59 HIS A CD2 1 ATOM 458 C CE1 . HIS A 1 59 ? 1.530 14.678 3.953 1.00 21.59 ? 59 HIS A CE1 1 ATOM 459 N NE2 . HIS A 1 59 ? 2.087 14.069 2.919 1.00 21.82 ? 59 HIS A NE2 1 ATOM 460 N N . PHE A 1 60 ? -2.065 13.330 5.354 1.00 23.90 ? 60 PHE A N 1 ATOM 461 C CA . PHE A 1 60 ? -2.403 13.883 6.665 1.00 23.96 ? 60 PHE A CA 1 ATOM 462 C C . PHE A 1 60 ? -2.451 15.421 6.713 1.00 24.29 ? 60 PHE A C 1 ATOM 463 O O . PHE A 1 60 ? -3.270 15.993 7.435 1.00 24.43 ? 60 PHE A O 1 ATOM 464 C CB . PHE A 1 60 ? -1.488 13.315 7.765 1.00 23.69 ? 60 PHE A CB 1 ATOM 465 C CG . PHE A 1 60 ? -1.760 13.884 9.129 1.00 22.90 ? 60 PHE A CG 1 ATOM 466 C CD1 . PHE A 1 60 ? -2.929 13.562 9.811 1.00 21.95 ? 60 PHE A CD1 1 ATOM 467 C CD2 . PHE A 1 60 ? -0.864 14.769 9.718 1.00 22.30 ? 60 PHE A CD2 1 ATOM 468 C CE1 . PHE A 1 60 ? -3.197 14.099 11.077 1.00 22.32 ? 60 PHE A CE1 1 ATOM 469 C CE2 . PHE A 1 60 ? -1.116 15.312 10.979 1.00 22.81 ? 60 PHE A CE2 1 ATOM 470 C CZ . PHE A 1 60 ? -2.285 14.977 11.664 1.00 21.98 ? 60 PHE A CZ 1 ATOM 471 N N . PHE A 1 61 ? -1.595 16.087 5.942 1.00 24.56 ? 61 PHE A N 1 ATOM 472 C CA . PHE A 1 61 ? -1.591 17.546 5.909 1.00 24.92 ? 61 PHE A CA 1 ATOM 473 C C . PHE A 1 61 ? -2.949 18.094 5.477 1.00 25.60 ? 61 PHE A C 1 ATOM 474 O O . PHE A 1 61 ? -3.447 19.059 6.059 1.00 25.73 ? 61 PHE A O 1 ATOM 475 C CB . PHE A 1 61 ? -0.503 18.095 4.982 1.00 24.81 ? 61 PHE A CB 1 ATOM 476 C CG . PHE A 1 61 ? 0.899 17.748 5.400 1.00 23.87 ? 61 PHE A CG 1 ATOM 477 C CD1 . PHE A 1 61 ? 1.177 17.306 6.691 1.00 22.67 ? 61 PHE A CD1 1 ATOM 478 C CD2 . PHE A 1 61 ? 1.951 17.895 4.497 1.00 22.99 ? 61 PHE A CD2 1 ATOM 479 C CE1 . PHE A 1 61 ? 2.471 16.984 7.062 1.00 22.48 ? 61 PHE A CE1 1 ATOM 480 C CE2 . PHE A 1 61 ? 3.253 17.577 4.862 1.00 21.79 ? 61 PHE A CE2 1 ATOM 481 C CZ . PHE A 1 61 ? 3.515 17.125 6.142 1.00 22.07 ? 61 PHE A CZ 1 ATOM 482 N N . GLN A 1 62 ? -3.545 17.465 4.468 1.00 26.08 ? 62 GLN A N 1 ATOM 483 C CA . GLN A 1 62 ? -4.848 17.880 3.959 1.00 26.63 ? 62 GLN A CA 1 ATOM 484 C C . GLN A 1 62 ? -6.003 17.294 4.762 1.00 26.95 ? 62 GLN A C 1 ATOM 485 O O . GLN A 1 62 ? -7.081 17.874 4.794 1.00 27.33 ? 62 GLN A O 1 ATOM 486 C CB . GLN A 1 62 ? -4.987 17.521 2.478 1.00 26.52 ? 62 GLN A CB 1 ATOM 487 C CG . GLN A 1 62 ? -4.264 18.489 1.537 1.00 27.51 ? 62 GLN A CG 1 ATOM 488 C CD . GLN A 1 62 ? -2.757 18.527 1.756 1.00 28.76 ? 62 GLN A CD 1 ATOM 489 O OE1 . GLN A 1 62 ? -2.209 19.533 2.214 1.00 29.42 ? 62 GLN A OE1 1 ATOM 490 N NE2 . GLN A 1 62 ? -2.084 17.425 1.437 1.00 29.55 ? 62 GLN A NE2 1 ATOM 491 N N . ALA A 1 63 ? -5.764 16.164 5.423 1.00 27.28 ? 63 ALA A N 1 ATOM 492 C CA . ALA A 1 63 ? -6.810 15.434 6.144 1.00 27.93 ? 63 ALA A CA 1 ATOM 493 C C . ALA A 1 63 ? -7.017 15.893 7.587 1.00 28.28 ? 63 ALA A C 1 ATOM 494 O O . ALA A 1 63 ? -8.070 15.641 8.168 1.00 28.42 ? 63 ALA A O 1 ATOM 495 C CB . ALA A 1 63 ? -6.523 13.928 6.110 1.00 27.84 ? 63 ALA A CB 1 ATOM 496 N N . LYS A 1 64 ? -6.014 16.559 8.153 1.00 28.94 ? 64 LYS A N 1 ATOM 497 C CA . LYS A 1 64 ? -6.010 16.935 9.575 1.00 29.83 ? 64 LYS A CA 1 ATOM 498 C C . LYS A 1 64 ? -7.262 17.706 10.024 1.00 30.10 ? 64 LYS A C 1 ATOM 499 O O . LYS A 1 64 ? -7.909 17.328 11.015 1.00 30.24 ? 64 LYS A O 1 ATOM 500 C CB . LYS A 1 64 ? -4.732 17.707 9.918 1.00 29.85 ? 64 LYS A CB 1 ATOM 501 C CG . LYS A 1 64 ? -4.627 18.134 11.358 1.00 30.86 ? 64 LYS A CG 1 ATOM 502 C CD . LYS A 1 64 ? -3.492 19.118 11.536 1.00 32.35 ? 64 LYS A CD 1 ATOM 503 C CE . LYS A 1 64 ? -3.569 19.762 12.906 1.00 33.78 ? 64 LYS A CE 1 ATOM 504 N NZ . LYS A 1 64 ? -2.454 20.725 13.116 1.00 34.96 ? 64 LYS A NZ 1 ATOM 505 N N . HIS A 1 65 ? -7.609 18.760 9.286 1.00 30.26 ? 65 HIS A N 1 ATOM 506 C CA . HIS A 1 65 ? -8.796 19.562 9.597 1.00 30.82 ? 65 HIS A CA 1 ATOM 507 C C . HIS A 1 65 ? -10.102 18.757 9.562 1.00 30.62 ? 65 HIS A C 1 ATOM 508 O O . HIS A 1 65 ? -11.035 19.057 10.302 1.00 30.73 ? 65 HIS A O 1 ATOM 509 C CB . HIS A 1 65 ? -8.876 20.822 8.719 1.00 31.13 ? 65 HIS A CB 1 ATOM 510 C CG . HIS A 1 65 ? -9.236 20.560 7.287 1.00 33.03 ? 65 HIS A CG 1 ATOM 511 N ND1 . HIS A 1 65 ? -10.510 20.750 6.790 1.00 34.32 ? 65 HIS A ND1 1 ATOM 512 C CD2 . HIS A 1 65 ? -8.485 20.146 6.239 1.00 34.33 ? 65 HIS A CD2 1 ATOM 513 C CE1 . HIS A 1 65 ? -10.531 20.447 5.505 1.00 34.65 ? 65 HIS A CE1 1 ATOM 514 N NE2 . HIS A 1 65 ? -9.316 20.076 5.146 1.00 35.06 ? 65 HIS A NE2 1 ATOM 515 N N . LEU A 1 66 ? -10.147 17.724 8.724 1.00 30.37 ? 66 LEU A N 1 ATOM 516 C CA . LEU A 1 66 ? -11.295 16.824 8.667 1.00 30.03 ? 66 LEU A CA 1 ATOM 517 C C . LEU A 1 66 ? -11.330 15.849 9.851 1.00 30.09 ? 66 LEU A C 1 ATOM 518 O O . LEU A 1 66 ? -12.405 15.541 10.379 1.00 30.00 ? 66 LEU A O 1 ATOM 519 C CB . LEU A 1 66 ? -11.332 16.064 7.334 1.00 29.89 ? 66 LEU A CB 1 ATOM 520 C CG . LEU A 1 66 ? -11.517 16.888 6.048 1.00 29.79 ? 66 LEU A CG 1 ATOM 521 C CD1 . LEU A 1 66 ? -11.190 16.054 4.816 1.00 28.86 ? 66 LEU A CD1 1 ATOM 522 C CD2 . LEU A 1 66 ? -12.915 17.509 5.932 1.00 28.06 ? 66 LEU A CD2 1 ATOM 523 N N . ILE A 1 67 ? -10.155 15.377 10.268 1.00 30.09 ? 67 ILE A N 1 ATOM 524 C CA . ILE A 1 67 ? -10.030 14.488 11.427 1.00 30.08 ? 67 ILE A CA 1 ATOM 525 C C . ILE A 1 67 ? -10.477 15.212 12.696 1.00 30.60 ? 67 ILE A C 1 ATOM 526 O O . ILE A 1 67 ? -11.068 14.609 13.590 1.00 30.42 ? 67 ILE A O 1 ATOM 527 C CB . ILE A 1 67 ? -8.575 13.958 11.586 1.00 29.95 ? 67 ILE A CB 1 ATOM 528 C CG1 . ILE A 1 67 ? -8.178 13.095 10.382 1.00 29.49 ? 67 ILE A CG1 1 ATOM 529 C CG2 . ILE A 1 67 ? -8.407 13.179 12.875 1.00 29.31 ? 67 ILE A CG2 1 ATOM 530 C CD1 . ILE A 1 67 ? -6.711 12.678 10.364 1.00 28.89 ? 67 ILE A CD1 1 ATOM 531 N N . GLU A 1 68 ? -10.203 16.512 12.752 1.00 31.37 ? 68 GLU A N 1 ATOM 532 C CA . GLU A 1 68 ? -10.550 17.339 13.901 1.00 32.16 ? 68 GLU A CA 1 ATOM 533 C C . GLU A 1 68 ? -12.050 17.588 14.039 1.00 32.45 ? 68 GLU A C 1 ATOM 534 O O . GLU A 1 68 ? -12.525 17.894 15.126 1.00 32.37 ? 68 GLU A O 1 ATOM 535 C CB . GLU A 1 68 ? -9.771 18.650 13.858 1.00 32.27 ? 68 GLU A CB 1 ATOM 536 C CG . GLU A 1 68 ? -8.373 18.504 14.435 1.00 33.85 ? 68 GLU A CG 1 ATOM 537 C CD . GLU A 1 68 ? -7.418 19.608 14.022 1.00 36.59 ? 68 GLU A CD 1 ATOM 538 O OE1 . GLU A 1 68 ? -7.796 20.487 13.217 1.00 38.47 ? 68 GLU A OE1 1 ATOM 539 O OE2 . GLU A 1 68 ? -6.270 19.594 14.509 1.00 37.49 ? 68 GLU A OE2 1 ATOM 540 N N . ARG A 1 69 ? -12.784 17.427 12.940 1.00 33.17 ? 69 ARG A N 1 ATOM 541 C CA . ARG A 1 69 ? -14.248 17.557 12.933 1.00 33.77 ? 69 ARG A CA 1 ATOM 542 C C . ARG A 1 69 ? -14.948 16.234 13.201 1.00 33.11 ? 69 ARG A C 1 ATOM 543 O O . ARG A 1 69 ? -16.174 16.169 13.168 1.00 33.44 ? 69 ARG A O 1 ATOM 544 C CB . ARG A 1 69 ? -14.731 18.119 11.588 1.00 34.18 ? 69 ARG A CB 1 ATOM 545 C CG . ARG A 1 69 ? -14.579 19.632 11.443 1.00 37.53 ? 69 ARG A CG 1 ATOM 546 C CD . ARG A 1 69 ? -14.373 20.063 9.976 1.00 43.97 ? 69 ARG A CD 1 ATOM 547 N NE . ARG A 1 69 ? -15.537 19.805 9.115 1.00 48.89 ? 69 ARG A NE 1 ATOM 548 C CZ . ARG A 1 69 ? -15.577 20.011 7.794 1.00 51.33 ? 69 ARG A CZ 1 ATOM 549 N NH1 . ARG A 1 69 ? -14.516 20.486 7.144 1.00 52.40 ? 69 ARG A NH1 1 ATOM 550 N NH2 . ARG A 1 69 ? -16.687 19.738 7.113 1.00 52.28 ? 69 ARG A NH2 1 ATOM 551 N N . SER A 1 70 ? -14.175 15.182 13.458 1.00 32.35 ? 70 SER A N 1 ATOM 552 C CA . SER A 1 70 ? -14.728 13.828 13.589 1.00 31.49 ? 70 SER A CA 1 ATOM 553 C C . SER A 1 70 ? -15.114 13.480 15.019 1.00 31.42 ? 70 SER A C 1 ATOM 554 O O . SER A 1 70 ? -14.311 13.625 15.952 1.00 31.36 ? 70 SER A O 1 ATOM 555 C CB . SER A 1 70 ? -13.753 12.779 13.043 1.00 31.15 ? 70 SER A CB 1 ATOM 556 O OG . SER A 1 70 ? -14.073 11.485 13.529 1.00 29.75 ? 70 SER A OG 1 ATOM 557 N N . GLN A 1 71 ? -16.342 13.000 15.174 1.00 31.10 ? 71 GLN A N 1 ATOM 558 C CA . GLN A 1 71 ? -16.841 12.528 16.460 1.00 30.96 ? 71 GLN A CA 1 ATOM 559 C C . GLN A 1 71 ? -16.021 11.356 16.981 1.00 30.35 ? 71 GLN A C 1 ATOM 560 O O . GLN A 1 71 ? -15.866 11.201 18.191 1.00 30.47 ? 71 GLN A O 1 ATOM 561 C CB . GLN A 1 71 ? -18.311 12.115 16.350 1.00 31.28 ? 71 GLN A CB 1 ATOM 562 C CG . GLN A 1 71 ? -19.234 13.198 15.825 1.00 32.92 ? 71 GLN A CG 1 ATOM 563 C CD . GLN A 1 71 ? -19.344 14.383 16.770 1.00 36.11 ? 71 GLN A CD 1 ATOM 564 O OE1 . GLN A 1 71 ? -19.127 14.254 17.980 1.00 36.51 ? 71 GLN A OE1 1 ATOM 565 N NE2 . GLN A 1 71 ? -19.687 15.549 16.220 1.00 37.15 ? 71 GLN A NE2 1 ATOM 566 N N . VAL A 1 72 ? -15.512 10.532 16.067 1.00 29.59 ? 72 VAL A N 1 ATOM 567 C CA . VAL A 1 72 ? -14.621 9.418 16.422 1.00 29.02 ? 72 VAL A CA 1 ATOM 568 C C . VAL A 1 72 ? -13.288 9.933 17.000 1.00 28.90 ? 72 VAL A C 1 ATOM 569 O O . VAL A 1 72 ? -12.855 9.486 18.070 1.00 28.59 ? 72 VAL A O 1 ATOM 570 C CB . VAL A 1 72 ? -14.378 8.459 15.220 1.00 28.93 ? 72 VAL A CB 1 ATOM 571 C CG1 . VAL A 1 72 ? -13.273 7.447 15.537 1.00 28.46 ? 72 VAL A CG1 1 ATOM 572 C CG2 . VAL A 1 72 ? -15.662 7.738 14.846 1.00 28.74 ? 72 VAL A CG2 1 ATOM 573 N N . PHE A 1 73 ? -12.658 10.878 16.300 1.00 28.59 ? 73 PHE A N 1 ATOM 574 C CA . PHE A 1 73 ? -11.462 11.540 16.805 1.00 28.72 ? 73 PHE A CA 1 ATOM 575 C C . PHE A 1 73 ? -11.715 12.103 18.199 1.00 29.12 ? 73 PHE A C 1 ATOM 576 O O . PHE A 1 73 ? -10.933 11.880 19.125 1.00 28.93 ? 73 PHE A O 1 ATOM 577 C CB . PHE A 1 73 ? -11.004 12.655 15.857 1.00 28.33 ? 73 PHE A CB 1 ATOM 578 C CG . PHE A 1 73 ? -9.791 13.409 16.343 1.00 27.70 ? 73 PHE A CG 1 ATOM 579 C CD1 . PHE A 1 73 ? -8.528 12.798 16.361 1.00 26.36 ? 73 PHE A CD1 1 ATOM 580 C CD2 . PHE A 1 73 ? -9.908 14.728 16.792 1.00 26.91 ? 73 PHE A CD2 1 ATOM 581 C CE1 . PHE A 1 73 ? -7.387 13.488 16.813 1.00 26.30 ? 73 PHE A CE1 1 ATOM 582 C CE2 . PHE A 1 73 ? -8.777 15.437 17.245 1.00 27.16 ? 73 PHE A CE2 1 ATOM 583 C CZ . PHE A 1 73 ? -7.505 14.807 17.256 1.00 26.25 ? 73 PHE A CZ 1 ATOM 584 N N . ASN A 1 74 ? -12.825 12.823 18.337 1.00 29.84 ? 74 ASN A N 1 ATOM 585 C CA . ASN A 1 74 ? -13.208 13.405 19.612 1.00 30.38 ? 74 ASN A CA 1 ATOM 586 C C . ASN A 1 74 ? -13.186 12.375 20.747 1.00 29.96 ? 74 ASN A C 1 ATOM 587 O O . ASN A 1 74 ? -12.599 12.623 21.806 1.00 29.88 ? 74 ASN A O 1 ATOM 588 C CB . ASN A 1 74 ? -14.580 14.049 19.501 1.00 30.98 ? 74 ASN A CB 1 ATOM 589 C CG . ASN A 1 74 ? -14.940 14.847 20.726 1.00 33.81 ? 74 ASN A CG 1 ATOM 590 O OD1 . ASN A 1 74 ? -14.362 15.902 20.987 1.00 37.20 ? 74 ASN A OD1 1 ATOM 591 N ND2 . ASN A 1 74 ? -15.900 14.344 21.497 1.00 36.57 ? 74 ASN A ND2 1 ATOM 592 N N . ILE A 1 75 ? -13.812 11.221 20.507 1.00 29.31 ? 75 ILE A N 1 ATOM 593 C CA . ILE A 1 75 ? -13.831 10.128 21.469 1.00 29.00 ? 75 ILE A CA 1 ATOM 594 C C . ILE A 1 75 ? -12.415 9.618 21.768 1.00 29.16 ? 75 ILE A C 1 ATOM 595 O O . ILE A 1 75 ? -12.090 9.337 22.913 1.00 29.12 ? 75 ILE A O 1 ATOM 596 C CB . ILE A 1 75 ? -14.795 8.991 21.012 1.00 29.03 ? 75 ILE A CB 1 ATOM 597 C CG1 . ILE A 1 75 ? -16.245 9.386 21.316 1.00 29.04 ? 75 ILE A CG1 1 ATOM 598 C CG2 . ILE A 1 75 ? -14.487 7.661 21.706 1.00 27.88 ? 75 ILE A CG2 1 ATOM 599 C CD1 . ILE A 1 75 ? -17.281 8.623 20.508 1.00 29.50 ? 75 ILE A CD1 1 ATOM 600 N N . LEU A 1 76 ? -11.573 9.538 20.739 1.00 29.49 ? 76 LEU A N 1 ATOM 601 C CA . LEU A 1 76 ? -10.203 9.046 20.885 1.00 29.58 ? 76 LEU A CA 1 ATOM 602 C C . LEU A 1 76 ? -9.299 10.009 21.656 1.00 30.34 ? 76 LEU A C 1 ATOM 603 O O . LEU A 1 76 ? -8.351 9.569 22.316 1.00 29.99 ? 76 LEU A O 1 ATOM 604 C CB . LEU A 1 76 ? -9.594 8.702 19.520 1.00 29.21 ? 76 LEU A CB 1 ATOM 605 C CG . LEU A 1 76 ? -10.252 7.587 18.700 1.00 27.85 ? 76 LEU A CG 1 ATOM 606 C CD1 . LEU A 1 76 ? -9.575 7.480 17.373 1.00 25.00 ? 76 LEU A CD1 1 ATOM 607 C CD2 . LEU A 1 76 ? -10.214 6.241 19.418 1.00 26.81 ? 76 LEU A CD2 1 ATOM 608 N N . ARG A 1 77 ? -9.594 11.310 21.569 1.00 31.36 ? 77 ARG A N 1 ATOM 609 C CA . ARG A 1 77 ? -8.923 12.331 22.385 1.00 32.65 ? 77 ARG A CA 1 ATOM 610 C C . ARG A 1 77 ? -9.133 12.025 23.863 1.00 32.95 ? 77 ARG A C 1 ATOM 611 O O . ARG A 1 77 ? -8.203 12.129 24.661 1.00 33.06 ? 77 ARG A O 1 ATOM 612 C CB . ARG A 1 77 ? -9.463 13.746 22.083 1.00 33.08 ? 77 ARG A CB 1 ATOM 613 C CG . ARG A 1 77 ? -8.943 14.421 20.814 1.00 35.03 ? 77 ARG A CG 1 ATOM 614 C CD . ARG A 1 77 ? -7.430 14.569 20.840 1.00 39.82 ? 77 ARG A CD 1 ATOM 615 N NE . ARG A 1 77 ? -6.929 15.868 21.300 1.00 43.38 ? 77 ARG A NE 1 ATOM 616 C CZ . ARG A 1 77 ? -6.953 16.303 22.558 1.00 45.01 ? 77 ARG A CZ 1 ATOM 617 N NH1 . ARG A 1 77 ? -7.504 15.569 23.509 1.00 46.95 ? 77 ARG A NH1 1 ATOM 618 N NH2 . ARG A 1 77 ? -6.442 17.490 22.864 1.00 45.56 ? 77 ARG A NH2 1 ATOM 619 N N . MET A 1 78 ? -10.367 11.649 24.205 1.00 33.51 ? 78 MET A N 1 ATOM 620 C CA . MET A 1 78 ? -10.779 11.357 25.579 1.00 34.12 ? 78 MET A CA 1 ATOM 621 C C . MET A 1 78 ? -10.168 10.070 26.131 1.00 33.80 ? 78 MET A C 1 ATOM 622 O O . MET A 1 78 ? -10.021 9.922 27.341 1.00 33.98 ? 78 MET A O 1 ATOM 623 C CB . MET A 1 78 ? -12.306 11.237 25.664 1.00 34.56 ? 78 MET A CB 1 ATOM 624 C CG . MET A 1 78 ? -13.074 12.541 25.552 1.00 36.56 ? 78 MET A CG 1 ATOM 625 S SD . MET A 1 78 ? -14.801 12.293 25.040 1.00 43.05 ? 78 MET A SD 1 ATOM 626 C CE . MET A 1 78 ? -15.470 11.239 26.329 1.00 40.00 ? 78 MET A CE 1 ATOM 627 N N . MET A 1 79 ? -9.833 9.141 25.245 1.00 33.30 ? 79 MET A N 1 ATOM 628 C CA . MET A 1 79 ? -9.398 7.814 25.648 1.00 33.08 ? 79 MET A CA 1 ATOM 629 C C . MET A 1 79 ? -8.045 7.809 26.359 1.00 32.35 ? 79 MET A C 1 ATOM 630 O O . MET A 1 79 ? -7.074 8.366 25.844 1.00 31.97 ? 79 MET A O 1 ATOM 631 C CB . MET A 1 79 ? -9.337 6.903 24.430 1.00 33.48 ? 79 MET A CB 1 ATOM 632 C CG . MET A 1 79 ? -9.385 5.427 24.761 1.00 34.96 ? 79 MET A CG 1 ATOM 633 S SD . MET A 1 79 ? -9.070 4.394 23.316 1.00 36.89 ? 79 MET A SD 1 ATOM 634 C CE . MET A 1 79 ? -7.335 3.999 23.578 1.00 37.29 ? 79 MET A CE 1 ATOM 635 N N . PRO A 1 80 ? -7.981 7.179 27.550 1.00 31.82 ? 80 PRO A N 1 ATOM 636 C CA . PRO A 1 80 ? -6.689 6.903 28.191 1.00 31.26 ? 80 PRO A CA 1 ATOM 637 C C . PRO A 1 80 ? -5.908 5.904 27.344 1.00 30.56 ? 80 PRO A C 1 ATOM 638 O O . PRO A 1 80 ? -6.256 4.720 27.305 1.00 30.37 ? 80 PRO A O 1 ATOM 639 C CB . PRO A 1 80 ? -7.087 6.286 29.532 1.00 31.31 ? 80 PRO A CB 1 ATOM 640 C CG . PRO A 1 80 ? -8.460 5.724 29.301 1.00 31.40 ? 80 PRO A CG 1 ATOM 641 C CD . PRO A 1 80 ? -9.108 6.693 28.365 1.00 31.78 ? 80 PRO A CD 1 ATOM 642 N N . LYS A 1 81 ? -4.877 6.387 26.653 1.00 29.74 ? 81 LYS A N 1 ATOM 643 C CA . LYS A 1 81 ? -4.199 5.582 25.634 1.00 28.84 ? 81 LYS A CA 1 ATOM 644 C C . LYS A 1 81 ? -3.023 4.752 26.171 1.00 28.70 ? 81 LYS A C 1 ATOM 645 O O . LYS A 1 81 ? -2.486 3.885 25.476 1.00 28.74 ? 81 LYS A O 1 ATOM 646 C CB . LYS A 1 81 ? -3.806 6.460 24.450 1.00 28.40 ? 81 LYS A CB 1 ATOM 647 C CG . LYS A 1 81 ? -5.006 6.847 23.585 1.00 27.23 ? 81 LYS A CG 1 ATOM 648 C CD . LYS A 1 81 ? -4.679 7.973 22.619 1.00 24.89 ? 81 LYS A CD 1 ATOM 649 C CE . LYS A 1 81 ? -4.574 9.307 23.334 1.00 23.06 ? 81 LYS A CE 1 ATOM 650 N NZ . LYS A 1 81 ? -5.901 9.932 23.562 1.00 21.61 ? 81 LYS A NZ 1 ATOM 651 N N . GLY A 1 82 ? -2.657 5.000 27.424 1.00 28.29 ? 82 GLY A N 1 ATOM 652 C CA . GLY A 1 82 ? -1.577 4.266 28.069 1.00 27.96 ? 82 GLY A CA 1 ATOM 653 C C . GLY A 1 82 ? -0.251 4.987 27.942 1.00 27.41 ? 82 GLY A C 1 ATOM 654 O O . GLY A 1 82 ? -0.054 6.036 28.549 1.00 27.46 ? 82 GLY A O 1 ATOM 655 N N . ALA A 1 83 ? 0.647 4.426 27.138 1.00 26.83 ? 83 ALA A N 1 ATOM 656 C CA . ALA A 1 83 ? 1.998 4.969 26.977 1.00 26.26 ? 83 ALA A CA 1 ATOM 657 C C . ALA A 1 83 ? 2.358 5.296 25.525 1.00 25.75 ? 83 ALA A C 1 ATOM 658 O O . ALA A 1 83 ? 1.884 4.650 24.580 1.00 25.61 ? 83 ALA A O 1 ATOM 659 C CB . ALA A 1 83 ? 3.022 4.009 27.573 1.00 26.29 ? 83 ALA A CB 1 ATOM 660 N N . ALA A 1 84 ? 3.192 6.315 25.358 1.00 25.08 ? 84 ALA A N 1 ATOM 661 C CA . ALA A 1 84 ? 3.794 6.611 24.061 1.00 24.47 ? 84 ALA A CA 1 ATOM 662 C C . ALA A 1 84 ? 5.200 6.020 24.082 1.00 24.32 ? 84 ALA A C 1 ATOM 663 O O . ALA A 1 84 ? 6.062 6.471 24.841 1.00 24.34 ? 84 ALA A O 1 ATOM 664 C CB . ALA A 1 84 ? 3.827 8.104 23.808 1.00 23.75 ? 84 ALA A CB 1 ATOM 665 N N . LEU A 1 85 ? 5.411 4.988 23.270 1.00 24.09 ? 85 LEU A N 1 ATOM 666 C CA . LEU A 1 85 ? 6.642 4.218 23.318 1.00 24.18 ? 85 LEU A CA 1 ATOM 667 C C . LEU A 1 85 ? 7.659 4.511 22.202 1.00 24.53 ? 85 LEU A C 1 ATOM 668 O O . LEU A 1 85 ? 8.825 4.113 22.311 1.00 24.85 ? 85 LEU A O 1 ATOM 669 C CB . LEU A 1 85 ? 6.321 2.720 23.399 1.00 24.01 ? 85 LEU A CB 1 ATOM 670 C CG . LEU A 1 85 ? 6.397 1.966 24.746 1.00 23.74 ? 85 LEU A CG 1 ATOM 671 C CD1 . LEU A 1 85 ? 6.107 2.823 25.991 1.00 22.10 ? 85 LEU A CD1 1 ATOM 672 C CD2 . LEU A 1 85 ? 5.518 0.721 24.712 1.00 22.69 ? 85 LEU A CD2 1 ATOM 673 N N . HIS A 1 86 ? 7.231 5.200 21.143 1.00 24.47 ? 86 HIS A N 1 ATOM 674 C CA . HIS A 1 86 ? 8.134 5.542 20.036 1.00 24.50 ? 86 HIS A CA 1 ATOM 675 C C . HIS A 1 86 ? 8.077 7.040 19.767 1.00 24.33 ? 86 HIS A C 1 ATOM 676 O O . HIS A 1 86 ? 7.198 7.519 19.056 1.00 23.85 ? 86 HIS A O 1 ATOM 677 C CB . HIS A 1 86 ? 7.813 4.733 18.768 1.00 24.38 ? 86 HIS A CB 1 ATOM 678 C CG . HIS A 1 86 ? 8.881 4.800 17.715 1.00 25.58 ? 86 HIS A CG 1 ATOM 679 N ND1 . HIS A 1 86 ? 9.690 3.728 17.403 1.00 26.17 ? 86 HIS A ND1 1 ATOM 680 C CD2 . HIS A 1 86 ? 9.275 5.813 16.904 1.00 26.50 ? 86 HIS A CD2 1 ATOM 681 C CE1 . HIS A 1 86 ? 10.537 4.079 16.451 1.00 26.47 ? 86 HIS A CE1 1 ATOM 682 N NE2 . HIS A 1 86 ? 10.305 5.337 16.129 1.00 26.60 ? 86 HIS A NE2 1 ATOM 683 N N . LEU A 1 87 ? 9.022 7.764 20.357 1.00 24.60 ? 87 LEU A N 1 ATOM 684 C CA . LEU A 1 87 ? 9.113 9.219 20.234 1.00 25.29 ? 87 LEU A CA 1 ATOM 685 C C . LEU A 1 87 ? 10.556 9.655 20.139 1.00 25.98 ? 87 LEU A C 1 ATOM 686 O O . LEU A 1 87 ? 11.453 8.967 20.626 1.00 26.11 ? 87 LEU A O 1 ATOM 687 C CB . LEU A 1 87 ? 8.481 9.918 21.445 1.00 24.98 ? 87 LEU A CB 1 ATOM 688 C CG . LEU A 1 87 ? 6.998 9.707 21.755 1.00 24.55 ? 87 LEU A CG 1 ATOM 689 C CD1 . LEU A 1 87 ? 6.690 10.302 23.112 1.00 26.62 ? 87 LEU A CD1 1 ATOM 690 C CD2 . LEU A 1 87 ? 6.101 10.297 20.674 1.00 22.74 ? 87 LEU A CD2 1 ATOM 691 N N . HIS A 1 88 ? 10.773 10.816 19.535 1.00 27.09 ? 88 HIS A N 1 ATOM 692 C CA . HIS A 1 88 ? 12.116 11.389 19.448 1.00 28.29 ? 88 HIS A CA 1 ATOM 693 C C . HIS A 1 88 ? 12.262 12.665 20.257 1.00 28.74 ? 88 HIS A C 1 ATOM 694 O O . HIS A 1 88 ? 11.329 13.469 20.341 1.00 29.03 ? 88 HIS A O 1 ATOM 695 C CB . HIS A 1 88 ? 12.530 11.591 17.989 1.00 28.40 ? 88 HIS A CB 1 ATOM 696 C CG . HIS A 1 88 ? 12.664 10.304 17.243 1.00 29.49 ? 88 HIS A CG 1 ATOM 697 N ND1 . HIS A 1 88 ? 13.835 9.579 17.216 1.00 30.50 ? 88 HIS A ND1 1 ATOM 698 C CD2 . HIS A 1 88 ? 11.755 9.576 16.554 1.00 30.28 ? 88 HIS A CD2 1 ATOM 699 C CE1 . HIS A 1 88 ? 13.649 8.469 16.522 1.00 30.13 ? 88 HIS A CE1 1 ATOM 700 N NE2 . HIS A 1 88 ? 12.396 8.444 16.108 1.00 30.80 ? 88 HIS A NE2 1 ATOM 701 N N . ASP A 1 89 ? 13.443 12.833 20.846 1.00 29.22 ? 89 ASP A N 1 ATOM 702 C CA . ASP A 1 89 ? 13.744 13.953 21.740 1.00 29.81 ? 89 ASP A CA 1 ATOM 703 C C . ASP A 1 89 ? 13.145 15.297 21.322 1.00 29.96 ? 89 ASP A C 1 ATOM 704 O O . ASP A 1 89 ? 12.519 15.969 22.143 1.00 30.35 ? 89 ASP A O 1 ATOM 705 C CB . ASP A 1 89 ? 15.262 14.079 22.000 1.00 29.64 ? 89 ASP A CB 1 ATOM 706 C CG . ASP A 1 89 ? 16.105 14.038 20.717 1.00 30.83 ? 89 ASP A CG 1 ATOM 707 O OD1 . ASP A 1 89 ? 15.557 14.151 19.592 1.00 31.46 ? 89 ASP A OD1 1 ATOM 708 O OD2 . ASP A 1 89 ? 17.339 13.887 20.840 1.00 31.27 ? 89 ASP A OD2 1 ATOM 709 N N . ILE A 1 90 ? 13.316 15.683 20.060 1.00 30.00 ? 90 ILE A N 1 ATOM 710 C CA . ILE A 1 90 ? 12.952 17.040 19.644 1.00 30.13 ? 90 ILE A CA 1 ATOM 711 C C . ILE A 1 90 ? 11.813 17.134 18.617 1.00 30.13 ? 90 ILE A C 1 ATOM 712 O O . ILE A 1 90 ? 11.710 18.114 17.879 1.00 30.64 ? 90 ILE A O 1 ATOM 713 C CB . ILE A 1 90 ? 14.191 17.872 19.181 1.00 30.16 ? 90 ILE A CB 1 ATOM 714 C CG1 . ILE A 1 90 ? 14.863 17.251 17.956 1.00 29.97 ? 90 ILE A CG1 1 ATOM 715 C CG2 . ILE A 1 90 ? 15.195 18.052 20.324 1.00 30.28 ? 90 ILE A CG2 1 ATOM 716 C CD1 . ILE A 1 90 ? 15.899 18.184 17.300 1.00 31.12 ? 90 ILE A CD1 1 ATOM 717 N N . GLY A 1 91 ? 10.939 16.139 18.594 1.00 29.94 ? 91 GLY A N 1 ATOM 718 C CA . GLY A 1 91 ? 9.810 16.160 17.676 1.00 29.55 ? 91 GLY A CA 1 ATOM 719 C C . GLY A 1 91 ? 8.459 16.034 18.351 1.00 29.63 ? 91 GLY A C 1 ATOM 720 O O . GLY A 1 91 ? 7.468 15.710 17.700 1.00 29.55 ? 91 GLY A O 1 ATOM 721 N N . ILE A 1 92 ? 8.412 16.316 19.650 1.00 29.65 ? 92 ILE A N 1 ATOM 722 C CA . ILE A 1 92 ? 7.237 15.990 20.471 1.00 29.90 ? 92 ILE A CA 1 ATOM 723 C C . ILE A 1 92 ? 6.455 17.176 21.054 1.00 30.30 ? 92 ILE A C 1 ATOM 724 O O . ILE A 1 92 ? 5.503 16.970 21.815 1.00 30.22 ? 92 ILE A O 1 ATOM 725 C CB . ILE A 1 92 ? 7.604 14.976 21.599 1.00 29.64 ? 92 ILE A CB 1 ATOM 726 C CG1 . ILE A 1 92 ? 8.812 15.470 22.409 1.00 29.05 ? 92 ILE A CG1 1 ATOM 727 C CG2 . ILE A 1 92 ? 7.857 13.603 20.991 1.00 29.36 ? 92 ILE A CG2 1 ATOM 728 C CD1 . ILE A 1 92 ? 9.378 14.467 23.400 1.00 27.43 ? 92 ILE A CD1 1 ATOM 729 N N . VAL A 1 93 ? 6.853 18.399 20.694 1.00 30.67 ? 93 VAL A N 1 ATOM 730 C CA . VAL A 1 93 ? 6.225 19.621 21.208 1.00 31.24 ? 93 VAL A CA 1 ATOM 731 C C . VAL A 1 93 ? 5.788 20.504 20.049 1.00 31.95 ? 93 VAL A C 1 ATOM 732 O O . VAL A 1 93 ? 6.585 20.796 19.155 1.00 31.98 ? 93 VAL A O 1 ATOM 733 C CB . VAL A 1 93 ? 7.195 20.422 22.119 1.00 31.31 ? 93 VAL A CB 1 ATOM 734 C CG1 . VAL A 1 93 ? 6.614 21.782 22.500 1.00 30.65 ? 93 VAL A CG1 1 ATOM 735 C CG2 . VAL A 1 93 ? 7.564 19.621 23.362 1.00 30.62 ? 93 VAL A CG2 1 ATOM 736 N N . THR A 1 94 ? 4.524 20.926 20.071 1.00 32.96 ? 94 THR A N 1 ATOM 737 C CA . THR A 1 94 ? 3.955 21.768 19.016 1.00 34.06 ? 94 THR A CA 1 ATOM 738 C C . THR A 1 94 ? 4.862 22.970 18.744 1.00 34.97 ? 94 THR A C 1 ATOM 739 O O . THR A 1 94 ? 5.280 23.671 19.671 1.00 35.21 ? 94 THR A O 1 ATOM 740 C CB . THR A 1 94 ? 2.525 22.228 19.365 1.00 33.85 ? 94 THR A CB 1 ATOM 741 O OG1 . THR A 1 94 ? 1.747 21.092 19.748 1.00 34.26 ? 94 THR A OG1 1 ATOM 742 C CG2 . THR A 1 94 ? 1.855 22.883 18.174 1.00 33.83 ? 94 THR A CG2 1 ATOM 743 N N . MET A 1 95 ? 5.169 23.185 17.468 1.00 36.07 ? 95 MET A N 1 ATOM 744 C CA . MET A 1 95 ? 6.124 24.211 17.044 1.00 37.29 ? 95 MET A CA 1 ATOM 745 C C . MET A 1 95 ? 5.631 25.635 17.290 1.00 38.09 ? 95 MET A C 1 ATOM 746 O O . MET A 1 95 ? 6.429 26.556 17.408 1.00 38.21 ? 95 MET A O 1 ATOM 747 C CB . MET A 1 95 ? 6.493 24.030 15.570 1.00 37.19 ? 95 MET A CB 1 ATOM 748 C CG . MET A 1 95 ? 7.217 22.743 15.256 1.00 36.84 ? 95 MET A CG 1 ATOM 749 S SD . MET A 1 95 ? 8.819 22.624 16.063 1.00 37.69 ? 95 MET A SD 1 ATOM 750 C CE . MET A 1 95 ? 9.370 21.035 15.419 1.00 35.69 ? 95 MET A CE 1 ATOM 751 N N . ASP A 1 96 ? 4.316 25.797 17.365 1.00 39.42 ? 96 ASP A N 1 ATOM 752 C CA . ASP A 1 96 ? 3.688 27.048 17.792 1.00 40.77 ? 96 ASP A CA 1 ATOM 753 C C . ASP A 1 96 ? 4.420 27.683 18.987 1.00 40.76 ? 96 ASP A C 1 ATOM 754 O O . ASP A 1 96 ? 4.831 28.847 18.928 1.00 40.75 ? 96 ASP A O 1 ATOM 755 C CB . ASP A 1 96 ? 2.236 26.772 18.175 1.00 41.55 ? 96 ASP A CB 1 ATOM 756 C CG . ASP A 1 96 ? 1.307 27.885 17.765 1.00 44.43 ? 96 ASP A CG 1 ATOM 757 O OD1 . ASP A 1 96 ? 0.925 28.694 18.636 1.00 48.80 ? 96 ASP A OD1 1 ATOM 758 O OD2 . ASP A 1 96 ? 0.960 27.963 16.571 1.00 48.03 ? 96 ASP A OD2 1 ATOM 759 N N . TRP A 1 97 ? 4.582 26.901 20.056 1.00 40.70 ? 97 TRP A N 1 ATOM 760 C CA . TRP A 1 97 ? 5.300 27.314 21.262 1.00 40.60 ? 97 TRP A CA 1 ATOM 761 C C . TRP A 1 97 ? 6.787 27.630 21.024 1.00 40.62 ? 97 TRP A C 1 ATOM 762 O O . TRP A 1 97 ? 7.330 28.523 21.673 1.00 40.73 ? 97 TRP A O 1 ATOM 763 C CB . TRP A 1 97 ? 5.134 26.252 22.356 1.00 40.64 ? 97 TRP A CB 1 ATOM 764 C CG . TRP A 1 97 ? 5.889 26.518 23.635 1.00 40.73 ? 97 TRP A CG 1 ATOM 765 C CD1 . TRP A 1 97 ? 5.464 27.263 24.692 1.00 40.93 ? 97 TRP A CD1 1 ATOM 766 C CD2 . TRP A 1 97 ? 7.187 26.017 23.994 1.00 40.42 ? 97 TRP A CD2 1 ATOM 767 N NE1 . TRP A 1 97 ? 6.415 27.271 25.682 1.00 40.49 ? 97 TRP A NE1 1 ATOM 768 C CE2 . TRP A 1 97 ? 7.482 26.512 25.285 1.00 40.41 ? 97 TRP A CE2 1 ATOM 769 C CE3 . TRP A 1 97 ? 8.128 25.197 23.353 1.00 40.36 ? 97 TRP A CE3 1 ATOM 770 C CZ2 . TRP A 1 97 ? 8.680 26.216 25.951 1.00 40.33 ? 97 TRP A CZ2 1 ATOM 771 C CZ3 . TRP A 1 97 ? 9.327 24.907 24.015 1.00 40.08 ? 97 TRP A CZ3 1 ATOM 772 C CH2 . TRP A 1 97 ? 9.588 25.417 25.301 1.00 40.14 ? 97 TRP A CH2 1 ATOM 773 N N . LEU A 1 98 ? 7.444 26.919 20.108 1.00 40.51 ? 98 LEU A N 1 ATOM 774 C CA . LEU A 1 98 ? 8.837 27.243 19.777 1.00 40.69 ? 98 LEU A CA 1 ATOM 775 C C . LEU A 1 98 ? 8.988 28.642 19.191 1.00 41.37 ? 98 LEU A C 1 ATOM 776 O O . LEU A 1 98 ? 9.912 29.371 19.549 1.00 41.28 ? 98 LEU A O 1 ATOM 777 C CB . LEU A 1 98 ? 9.458 26.222 18.816 1.00 40.45 ? 98 LEU A CB 1 ATOM 778 C CG . LEU A 1 98 ? 10.305 25.062 19.353 1.00 39.33 ? 98 LEU A CG 1 ATOM 779 C CD1 . LEU A 1 98 ? 11.209 24.556 18.237 1.00 37.73 ? 98 LEU A CD1 1 ATOM 780 C CD2 . LEU A 1 98 ? 11.145 25.461 20.567 1.00 38.15 ? 98 LEU A CD2 1 ATOM 781 N N . VAL A 1 99 ? 8.077 29.009 18.294 1.00 42.30 ? 99 VAL A N 1 ATOM 782 C CA . VAL A 1 99 ? 8.111 30.315 17.650 1.00 43.14 ? 99 VAL A CA 1 ATOM 783 C C . VAL A 1 99 ? 7.578 31.418 18.566 1.00 44.02 ? 99 VAL A C 1 ATOM 784 O O . VAL A 1 99 ? 8.291 32.374 18.864 1.00 44.06 ? 99 VAL A O 1 ATOM 785 C CB . VAL A 1 99 ? 7.338 30.312 16.313 1.00 43.14 ? 99 VAL A CB 1 ATOM 786 C CG1 . VAL A 1 99 ? 7.342 31.705 15.692 1.00 42.74 ? 99 VAL A CG1 1 ATOM 787 C CG2 . VAL A 1 99 ? 7.950 29.303 15.353 1.00 42.69 ? 99 VAL A CG2 1 ATOM 788 N N . ARG A 1 100 ? 6.331 31.269 19.010 1.00 45.16 ? 100 ARG A N 1 ATOM 789 C CA . ARG A 1 100 ? 5.636 32.301 19.783 1.00 46.39 ? 100 ARG A CA 1 ATOM 790 C C . ARG A 1 100 ? 6.242 32.565 21.159 1.00 46.19 ? 100 ARG A C 1 ATOM 791 O O . ARG A 1 100 ? 6.230 33.699 21.633 1.00 46.43 ? 100 ARG A O 1 ATOM 792 C CB . ARG A 1 100 ? 4.146 31.961 19.915 1.00 47.01 ? 100 ARG A CB 1 ATOM 793 C CG . ARG A 1 100 ? 3.329 32.239 18.645 1.00 50.78 ? 100 ARG A CG 1 ATOM 794 C CD . ARG A 1 100 ? 2.566 33.587 18.687 1.00 57.38 ? 100 ARG A CD 1 ATOM 795 N NE . ARG A 1 100 ? 3.340 34.711 19.236 1.00 61.86 ? 100 ARG A NE 1 ATOM 796 C CZ . ARG A 1 100 ? 2.977 35.446 20.290 1.00 64.07 ? 100 ARG A CZ 1 ATOM 797 N NH1 . ARG A 1 100 ? 1.834 35.205 20.926 1.00 64.78 ? 100 ARG A NH1 1 ATOM 798 N NH2 . ARG A 1 100 ? 3.758 36.439 20.704 1.00 64.82 ? 100 ARG A NH2 1 ATOM 799 N N . ASN A 1 101 ? 6.774 31.523 21.790 1.00 45.91 ? 101 ASN A N 1 ATOM 800 C CA . ASN A 1 101 ? 7.346 31.643 23.125 1.00 45.57 ? 101 ASN A CA 1 ATOM 801 C C . ASN A 1 101 ? 8.880 31.702 23.131 1.00 45.01 ? 101 ASN A C 1 ATOM 802 O O . ASN A 1 101 ? 9.463 32.655 23.653 1.00 45.20 ? 101 ASN A O 1 ATOM 803 C CB . ASN A 1 101 ? 6.832 30.503 24.012 1.00 45.93 ? 101 ASN A CB 1 ATOM 804 C CG . ASN A 1 101 ? 7.301 30.607 25.453 1.00 47.30 ? 101 ASN A CG 1 ATOM 805 O OD1 . ASN A 1 101 ? 8.506 30.576 25.745 1.00 46.93 ? 101 ASN A OD1 1 ATOM 806 N ND2 . ASN A 1 101 ? 6.341 30.712 26.368 1.00 49.23 ? 101 ASN A ND2 1 ATOM 807 N N . VAL A 1 102 ? 9.528 30.697 22.544 1.00 44.06 ? 102 VAL A N 1 ATOM 808 C CA . VAL A 1 102 ? 10.981 30.549 22.667 1.00 43.09 ? 102 VAL A CA 1 ATOM 809 C C . VAL A 1 102 ? 11.786 31.598 21.876 1.00 43.05 ? 102 VAL A C 1 ATOM 810 O O . VAL A 1 102 ? 12.773 32.131 22.391 1.00 42.71 ? 102 VAL A O 1 ATOM 811 C CB . VAL A 1 102 ? 11.437 29.088 22.365 1.00 42.93 ? 102 VAL A CB 1 ATOM 812 C CG1 . VAL A 1 102 ? 12.959 28.968 22.281 1.00 41.84 ? 102 VAL A CG1 1 ATOM 813 C CG2 . VAL A 1 102 ? 10.890 28.146 23.422 1.00 42.10 ? 102 VAL A CG2 1 ATOM 814 N N . THR A 1 103 ? 11.365 31.906 20.648 1.00 42.96 ? 103 THR A N 1 ATOM 815 C CA . THR A 1 103 ? 12.069 32.913 19.828 1.00 43.03 ? 103 THR A CA 1 ATOM 816 C C . THR A 1 103 ? 11.918 34.326 20.395 1.00 42.98 ? 103 THR A C 1 ATOM 817 O O . THR A 1 103 ? 12.666 35.235 20.017 1.00 42.88 ? 103 THR A O 1 ATOM 818 C CB . THR A 1 103 ? 11.599 32.944 18.353 1.00 42.84 ? 103 THR A CB 1 ATOM 819 O OG1 . THR A 1 103 ? 10.912 31.740 18.028 1.00 43.65 ? 103 THR A OG1 1 ATOM 820 C CG2 . THR A 1 103 ? 12.784 33.078 17.432 1.00 43.38 ? 103 THR A CG2 1 ATOM 821 N N . TYR A 1 104 ? 10.951 34.498 21.295 1.00 43.06 ? 104 TYR A N 1 ATOM 822 C CA . TYR A 1 104 ? 10.703 35.787 21.931 1.00 43.42 ? 104 TYR A CA 1 ATOM 823 C C . TYR A 1 104 ? 11.453 35.969 23.249 1.00 43.36 ? 104 TYR A C 1 ATOM 824 O O . TYR A 1 104 ? 11.335 37.010 23.896 1.00 43.62 ? 104 TYR A O 1 ATOM 825 C CB . TYR A 1 104 ? 9.204 36.005 22.134 1.00 43.42 ? 104 TYR A CB 1 ATOM 826 C CG . TYR A 1 104 ? 8.519 36.580 20.919 1.00 44.51 ? 104 TYR A CG 1 ATOM 827 C CD1 . TYR A 1 104 ? 7.934 35.747 19.963 1.00 45.25 ? 104 TYR A CD1 1 ATOM 828 C CD2 . TYR A 1 104 ? 8.465 37.960 20.715 1.00 45.41 ? 104 TYR A CD2 1 ATOM 829 C CE1 . TYR A 1 104 ? 7.304 36.272 18.842 1.00 46.00 ? 104 TYR A CE1 1 ATOM 830 C CE2 . TYR A 1 104 ? 7.838 38.498 19.596 1.00 45.92 ? 104 TYR A CE2 1 ATOM 831 C CZ . TYR A 1 104 ? 7.258 37.647 18.664 1.00 46.08 ? 104 TYR A CZ 1 ATOM 832 O OH . TYR A 1 104 ? 6.640 38.170 17.555 1.00 45.79 ? 104 TYR A OH 1 ATOM 833 N N . ARG A 1 105 ? 12.221 34.955 23.640 1.00 43.16 ? 105 ARG A N 1 ATOM 834 C CA . ARG A 1 105 ? 13.011 35.017 24.865 1.00 42.89 ? 105 ARG A CA 1 ATOM 835 C C . ARG A 1 105 ? 14.305 35.780 24.619 1.00 43.16 ? 105 ARG A C 1 ATOM 836 O O . ARG A 1 105 ? 14.880 35.684 23.537 1.00 43.15 ? 105 ARG A O 1 ATOM 837 C CB . ARG A 1 105 ? 13.311 33.615 25.396 1.00 42.48 ? 105 ARG A CB 1 ATOM 838 C CG . ARG A 1 105 ? 12.076 32.842 25.796 1.00 41.07 ? 105 ARG A CG 1 ATOM 839 C CD . ARG A 1 105 ? 12.426 31.423 26.184 1.00 39.20 ? 105 ARG A CD 1 ATOM 840 N NE . ARG A 1 105 ? 11.253 30.682 26.634 1.00 37.87 ? 105 ARG A NE 1 ATOM 841 C CZ . ARG A 1 105 ? 11.288 29.690 27.516 1.00 37.57 ? 105 ARG A CZ 1 ATOM 842 N NH1 . ARG A 1 105 ? 12.435 29.311 28.072 1.00 36.34 ? 105 ARG A NH1 1 ATOM 843 N NH2 . ARG A 1 105 ? 10.163 29.082 27.854 1.00 38.09 ? 105 ARG A NH2 1 ATOM 844 N N . PRO A 1 106 ? 14.763 36.545 25.628 1.00 43.59 ? 106 PRO A N 1 ATOM 845 C CA . PRO A 1 106 ? 16.003 37.320 25.540 1.00 43.91 ? 106 PRO A CA 1 ATOM 846 C C . PRO A 1 106 ? 17.181 36.518 24.994 1.00 44.39 ? 106 PRO A C 1 ATOM 847 O O . PRO A 1 106 ? 17.291 35.317 25.259 1.00 44.38 ? 106 PRO A O 1 ATOM 848 C CB . PRO A 1 106 ? 16.284 37.721 26.998 1.00 43.72 ? 106 PRO A CB 1 ATOM 849 C CG . PRO A 1 106 ? 15.191 37.081 27.839 1.00 43.64 ? 106 PRO A CG 1 ATOM 850 C CD . PRO A 1 106 ? 14.071 36.770 26.912 1.00 43.61 ? 106 PRO A CD 1 ATOM 851 N N . HIS A 1 107 ? 18.036 37.195 24.225 1.00 44.98 ? 107 HIS A N 1 ATOM 852 C CA . HIS A 1 107 ? 19.326 36.667 23.753 1.00 45.66 ? 107 HIS A CA 1 ATOM 853 C C . HIS A 1 107 ? 19.240 35.646 22.614 1.00 45.98 ? 107 HIS A C 1 ATOM 854 O O . HIS A 1 107 ? 20.238 34.989 22.282 1.00 45.91 ? 107 HIS A O 1 ATOM 855 C CB . HIS A 1 107 ? 20.173 36.120 24.916 1.00 45.87 ? 107 HIS A CB 1 ATOM 856 C CG . HIS A 1 107 ? 20.206 37.018 26.116 1.00 46.94 ? 107 HIS A CG 1 ATOM 857 N ND1 . HIS A 1 107 ? 20.729 38.294 26.080 1.00 48.56 ? 107 HIS A ND1 1 ATOM 858 C CD2 . HIS A 1 107 ? 19.780 36.821 27.385 1.00 47.23 ? 107 HIS A CD2 1 ATOM 859 C CE1 . HIS A 1 107 ? 20.617 38.845 27.275 1.00 48.79 ? 107 HIS A CE1 1 ATOM 860 N NE2 . HIS A 1 107 ? 20.047 37.971 28.086 1.00 48.55 ? 107 HIS A NE2 1 ATOM 861 N N . CYS A 1 108 ? 18.057 35.522 22.016 1.00 46.31 ? 108 CYS A N 1 ATOM 862 C CA . CYS A 1 108 ? 17.866 34.659 20.853 1.00 46.80 ? 108 CYS A CA 1 ATOM 863 C C . CYS A 1 108 ? 18.489 35.298 19.608 1.00 47.02 ? 108 CYS A C 1 ATOM 864 O O . CYS A 1 108 ? 18.166 36.439 19.265 1.00 46.99 ? 108 CYS A O 1 ATOM 865 C CB . CYS A 1 108 ? 16.373 34.387 20.622 1.00 46.87 ? 108 CYS A CB 1 ATOM 866 S SG . CYS A 1 108 ? 16.033 32.869 19.677 1.00 47.35 ? 108 CYS A SG 1 ATOM 867 N N . HIS A 1 109 ? 19.392 34.565 18.956 1.00 47.36 ? 109 HIS A N 1 ATOM 868 C CA . HIS A 1 109 ? 20.035 35.020 17.721 1.00 48.04 ? 109 HIS A CA 1 ATOM 869 C C . HIS A 1 109 ? 19.675 34.116 16.549 1.00 48.56 ? 109 HIS A C 1 ATOM 870 O O . HIS A 1 109 ? 19.553 32.898 16.711 1.00 48.57 ? 109 HIS A O 1 ATOM 871 C CB . HIS A 1 109 ? 21.561 35.040 17.861 1.00 47.91 ? 109 HIS A CB 1 ATOM 872 C CG . HIS A 1 109 ? 22.080 36.104 18.778 1.00 48.34 ? 109 HIS A CG 1 ATOM 873 N ND1 . HIS A 1 109 ? 22.061 35.978 20.150 1.00 48.82 ? 109 HIS A ND1 1 ATOM 874 C CD2 . HIS A 1 109 ? 22.653 37.303 18.519 1.00 48.56 ? 109 HIS A CD2 1 ATOM 875 C CE1 . HIS A 1 109 ? 22.589 37.059 20.697 1.00 49.36 ? 109 HIS A CE1 1 ATOM 876 N NE2 . HIS A 1 109 ? 22.955 37.879 19.729 1.00 48.94 ? 109 HIS A NE2 1 ATOM 877 N N . ILE A 1 110 ? 19.522 34.721 15.371 1.00 49.20 ? 110 ILE A N 1 ATOM 878 C CA . ILE A 1 110 ? 19.251 33.984 14.138 1.00 49.71 ? 110 ILE A CA 1 ATOM 879 C C . ILE A 1 110 ? 20.407 34.141 13.167 1.00 50.32 ? 110 ILE A C 1 ATOM 880 O O . ILE A 1 110 ? 21.154 35.116 13.227 1.00 50.24 ? 110 ILE A O 1 ATOM 881 C CB . ILE A 1 110 ? 17.914 34.419 13.469 1.00 49.74 ? 110 ILE A CB 1 ATOM 882 C CG1 . ILE A 1 110 ? 17.500 33.422 12.370 1.00 49.51 ? 110 ILE A CG1 1 ATOM 883 C CG2 . ILE A 1 110 ? 17.996 35.868 12.964 1.00 49.40 ? 110 ILE A CG2 1 ATOM 884 C CD1 . ILE A 1 110 ? 16.029 33.476 11.993 1.00 49.21 ? 110 ILE A CD1 1 ATOM 885 N N . CYS A 1 111 ? 20.546 33.168 12.274 1.00 51.28 ? 111 CYS A N 1 ATOM 886 C CA . CYS A 1 111 ? 21.600 33.181 11.273 1.00 52.26 ? 111 CYS A CA 1 ATOM 887 C C . CYS A 1 111 ? 21.230 32.308 10.077 1.00 52.24 ? 111 CYS A C 1 ATOM 888 O O . CYS A 1 111 ? 20.266 31.540 10.134 1.00 52.34 ? 111 CYS A O 1 ATOM 889 C CB . CYS A 1 111 ? 22.905 32.699 11.897 1.00 52.59 ? 111 CYS A CB 1 ATOM 890 S SG . CYS A 1 111 ? 24.275 32.619 10.766 1.00 55.76 ? 111 CYS A SG 1 ATOM 891 N N . PHE A 1 112 ? 21.998 32.445 8.997 1.00 52.45 ? 112 PHE A N 1 ATOM 892 C CA . PHE A 1 112 ? 21.834 31.627 7.803 1.00 52.62 ? 112 PHE A CA 1 ATOM 893 C C . PHE A 1 112 ? 23.189 31.148 7.303 1.00 53.16 ? 112 PHE A C 1 ATOM 894 O O . PHE A 1 112 ? 24.080 31.957 7.057 1.00 53.23 ? 112 PHE A O 1 ATOM 895 C CB . PHE A 1 112 ? 21.107 32.410 6.711 1.00 52.30 ? 112 PHE A CB 1 ATOM 896 C CG . PHE A 1 112 ? 19.687 32.745 7.053 1.00 51.41 ? 112 PHE A CG 1 ATOM 897 C CD1 . PHE A 1 112 ? 18.663 31.849 6.773 1.00 51.02 ? 112 PHE A CD1 1 ATOM 898 C CD2 . PHE A 1 112 ? 19.373 33.960 7.652 1.00 50.51 ? 112 PHE A CD2 1 ATOM 899 C CE1 . PHE A 1 112 ? 17.341 32.158 7.088 1.00 50.72 ? 112 PHE A CE1 1 ATOM 900 C CE2 . PHE A 1 112 ? 18.059 34.278 7.972 1.00 50.35 ? 112 PHE A CE2 1 ATOM 901 C CZ . PHE A 1 112 ? 17.039 33.374 7.690 1.00 50.34 ? 112 PHE A CZ 1 ATOM 902 N N . THR A 1 113 ? 23.330 29.827 7.168 1.00 53.99 ? 113 THR A N 1 ATOM 903 C CA . THR A 1 113 ? 24.532 29.173 6.620 1.00 54.74 ? 113 THR A CA 1 ATOM 904 C C . THR A 1 113 ? 24.848 29.711 5.226 1.00 55.14 ? 113 THR A C 1 ATOM 905 O O . THR A 1 113 ? 23.946 30.208 4.546 1.00 55.31 ? 113 THR A O 1 ATOM 906 C CB . THR A 1 113 ? 24.316 27.642 6.457 1.00 54.70 ? 113 THR A CB 1 ATOM 907 O OG1 . THR A 1 113 ? 23.052 27.263 7.008 1.00 55.51 ? 113 THR A OG1 1 ATOM 908 C CG2 . THR A 1 113 ? 25.421 26.854 7.136 1.00 54.90 ? 113 THR A CG2 1 ATOM 909 N N . PRO A 1 114 ? 26.122 29.621 4.788 1.00 55.59 ? 114 PRO A N 1 ATOM 910 C CA . PRO A 1 114 ? 26.423 29.905 3.386 1.00 55.75 ? 114 PRO A CA 1 ATOM 911 C C . PRO A 1 114 ? 25.321 29.418 2.433 1.00 55.88 ? 114 PRO A C 1 ATOM 912 O O . PRO A 1 114 ? 25.000 30.112 1.464 1.00 56.01 ? 114 PRO A O 1 ATOM 913 C CB . PRO A 1 114 ? 27.722 29.119 3.146 1.00 55.87 ? 114 PRO A CB 1 ATOM 914 C CG . PRO A 1 114 ? 28.336 28.902 4.534 1.00 55.72 ? 114 PRO A CG 1 ATOM 915 C CD . PRO A 1 114 ? 27.361 29.426 5.565 1.00 55.68 ? 114 PRO A CD 1 ATOM 916 N N . ARG A 1 115 ? 24.733 28.255 2.730 1.00 55.76 ? 115 ARG A N 1 ATOM 917 C CA . ARG A 1 115 ? 23.699 27.660 1.883 1.00 55.65 ? 115 ARG A CA 1 ATOM 918 C C . ARG A 1 115 ? 22.298 28.236 2.033 1.00 54.70 ? 115 ARG A C 1 ATOM 919 O O . ARG A 1 115 ? 21.437 27.975 1.192 1.00 54.85 ? 115 ARG A O 1 ATOM 920 C CB . ARG A 1 115 ? 23.642 26.155 2.092 1.00 56.27 ? 115 ARG A CB 1 ATOM 921 C CG . ARG A 1 115 ? 24.349 25.399 1.009 1.00 59.03 ? 115 ARG A CG 1 ATOM 922 C CD . ARG A 1 115 ? 24.090 23.910 1.128 1.00 63.82 ? 115 ARG A CD 1 ATOM 923 N NE . ARG A 1 115 ? 25.253 23.160 0.664 1.00 67.48 ? 115 ARG A NE 1 ATOM 924 C CZ . ARG A 1 115 ? 26.404 23.071 1.332 1.00 69.19 ? 115 ARG A CZ 1 ATOM 925 N NH1 . ARG A 1 115 ? 26.552 23.683 2.501 1.00 70.22 ? 115 ARG A NH1 1 ATOM 926 N NH2 . ARG A 1 115 ? 27.414 22.373 0.831 1.00 69.79 ? 115 ARG A NH2 1 ATOM 927 N N . GLY A 1 116 ? 22.066 28.993 3.104 1.00 53.67 ? 116 GLY A N 1 ATOM 928 C CA . GLY A 1 116 ? 20.751 29.588 3.369 1.00 51.92 ? 116 GLY A CA 1 ATOM 929 C C . GLY A 1 116 ? 19.901 28.826 4.374 1.00 50.67 ? 116 GLY A C 1 ATOM 930 O O . GLY A 1 116 ? 18.715 29.134 4.547 1.00 50.74 ? 116 GLY A O 1 ATOM 931 N N . ILE A 1 117 ? 20.498 27.836 5.041 1.00 49.21 ? 117 ILE A N 1 ATOM 932 C CA . ILE A 1 117 ? 19.797 27.097 6.093 1.00 47.83 ? 117 ILE A CA 1 ATOM 933 C C . ILE A 1 117 ? 19.724 27.943 7.361 1.00 46.78 ? 117 ILE A C 1 ATOM 934 O O . ILE A 1 117 ? 20.745 28.394 7.884 1.00 46.48 ? 117 ILE A O 1 ATOM 935 C CB . ILE A 1 117 ? 20.443 25.715 6.415 1.00 47.86 ? 117 ILE A CB 1 ATOM 936 C CG1 . ILE A 1 117 ? 20.594 24.858 5.148 1.00 48.05 ? 117 ILE A CG1 1 ATOM 937 C CG2 . ILE A 1 117 ? 19.619 24.970 7.476 1.00 47.53 ? 117 ILE A CG2 1 ATOM 938 C CD1 . ILE A 1 117 ? 21.537 23.671 5.304 1.00 48.41 ? 117 ILE A CD1 1 ATOM 939 N N . MET A 1 118 ? 18.503 28.157 7.835 1.00 45.51 ? 118 MET A N 1 ATOM 940 C CA . MET A 1 118 ? 18.254 28.850 9.087 1.00 44.56 ? 118 MET A CA 1 ATOM 941 C C . MET A 1 118 ? 18.892 28.111 10.270 1.00 44.12 ? 118 MET A C 1 ATOM 942 O O . MET A 1 118 ? 19.116 26.895 10.224 1.00 43.94 ? 118 MET A O 1 ATOM 943 C CB . MET A 1 118 ? 16.751 28.984 9.293 1.00 44.51 ? 118 MET A CB 1 ATOM 944 C CG . MET A 1 118 ? 16.331 30.028 10.287 1.00 44.20 ? 118 MET A CG 1 ATOM 945 S SD . MET A 1 118 ? 14.648 30.542 9.935 1.00 45.29 ? 118 MET A SD 1 ATOM 946 C CE . MET A 1 118 ? 13.734 29.068 10.380 1.00 44.16 ? 118 MET A CE 1 ATOM 947 N N . GLN A 1 119 ? 19.180 28.862 11.329 1.00 43.51 ? 119 GLN A N 1 ATOM 948 C CA . GLN A 1 119 ? 19.880 28.334 12.493 1.00 43.00 ? 119 GLN A CA 1 ATOM 949 C C . GLN A 1 119 ? 19.855 29.335 13.656 1.00 42.42 ? 119 GLN A C 1 ATOM 950 O O . GLN A 1 119 ? 19.797 30.551 13.445 1.00 42.27 ? 119 GLN A O 1 ATOM 951 C CB . GLN A 1 119 ? 21.285 27.900 12.072 1.00 42.99 ? 119 GLN A CB 1 ATOM 952 C CG . GLN A 1 119 ? 22.413 28.242 12.967 1.00 44.36 ? 119 GLN A CG 1 ATOM 953 C CD . GLN A 1 119 ? 23.732 28.025 12.268 1.00 47.31 ? 119 GLN A CD 1 ATOM 954 O OE1 . GLN A 1 119 ? 24.084 28.839 11.380 1.00 48.27 ? 119 GLN A OE1 1 ATOM 955 N NE2 . GLN A 1 119 ? 24.414 27.029 12.594 1.00 48.73 ? 119 GLN A NE2 1 ATOM 956 N N . PHE A 1 120 ? 19.862 28.816 14.882 1.00 41.96 ? 120 PHE A N 1 ATOM 957 C CA . PHE A 1 120 ? 19.620 29.634 16.074 1.00 41.40 ? 120 PHE A CA 1 ATOM 958 C C . PHE A 1 120 ? 20.655 29.411 17.166 1.00 41.29 ? 120 PHE A C 1 ATOM 959 O O . PHE A 1 120 ? 21.306 28.366 17.216 1.00 40.93 ? 120 PHE A O 1 ATOM 960 C CB . PHE A 1 120 ? 18.224 29.357 16.636 1.00 41.24 ? 120 PHE A CB 1 ATOM 961 C CG . PHE A 1 120 ? 17.110 29.806 15.743 1.00 40.86 ? 120 PHE A CG 1 ATOM 962 C CD1 . PHE A 1 120 ? 16.510 31.042 15.935 1.00 40.13 ? 120 PHE A CD1 1 ATOM 963 C CD2 . PHE A 1 120 ? 16.648 28.988 14.713 1.00 40.90 ? 120 PHE A CD2 1 ATOM 964 C CE1 . PHE A 1 120 ? 15.472 31.464 15.112 1.00 40.20 ? 120 PHE A CE1 1 ATOM 965 C CE2 . PHE A 1 120 ? 15.609 29.401 13.884 1.00 40.37 ? 120 PHE A CE2 1 ATOM 966 C CZ . PHE A 1 120 ? 15.019 30.637 14.086 1.00 40.20 ? 120 PHE A CZ 1 ATOM 967 N N . ARG A 1 121 ? 20.789 30.404 18.042 1.00 41.46 ? 121 ARG A N 1 ATOM 968 C CA . ARG A 1 121 ? 21.729 30.354 19.168 1.00 42.03 ? 121 ARG A CA 1 ATOM 969 C C . ARG A 1 121 ? 21.368 31.417 20.214 1.00 41.71 ? 121 ARG A C 1 ATOM 970 O O . ARG A 1 121 ? 21.180 32.590 19.895 1.00 41.60 ? 121 ARG A O 1 ATOM 971 C CB . ARG A 1 121 ? 23.175 30.501 18.652 1.00 42.27 ? 121 ARG A CB 1 ATOM 972 C CG . ARG A 1 121 ? 24.314 30.664 19.654 1.00 45.24 ? 121 ARG A CG 1 ATOM 973 C CD . ARG A 1 121 ? 24.839 29.395 20.263 1.00 51.42 ? 121 ARG A CD 1 ATOM 974 N NE . ARG A 1 121 ? 25.868 28.543 19.636 1.00 56.48 ? 121 ARG A NE 1 ATOM 975 C CZ . ARG A 1 121 ? 25.945 28.124 18.371 1.00 59.34 ? 121 ARG A CZ 1 ATOM 976 N NH1 . ARG A 1 121 ? 25.126 28.554 17.428 1.00 60.87 ? 121 ARG A NH1 1 ATOM 977 N NH2 . ARG A 1 121 ? 26.915 27.286 18.036 1.00 61.09 ? 121 ARG A NH2 1 ATOM 978 N N . PHE A 1 122 ? 21.221 30.977 21.459 1.00 41.78 ? 122 PHE A N 1 ATOM 979 C CA . PHE A 1 122 ? 21.090 31.883 22.590 1.00 41.81 ? 122 PHE A CA 1 ATOM 980 C C . PHE A 1 122 ? 22.483 32.172 23.106 1.00 42.63 ? 122 PHE A C 1 ATOM 981 O O . PHE A 1 122 ? 23.239 31.250 23.413 1.00 42.44 ? 122 PHE A O 1 ATOM 982 C CB . PHE A 1 122 ? 20.252 31.263 23.705 1.00 41.20 ? 122 PHE A CB 1 ATOM 983 C CG . PHE A 1 122 ? 18.788 31.273 23.439 1.00 39.31 ? 122 PHE A CG 1 ATOM 984 C CD1 . PHE A 1 122 ? 18.180 30.197 22.814 1.00 37.50 ? 122 PHE A CD1 1 ATOM 985 C CD2 . PHE A 1 122 ? 18.007 32.358 23.829 1.00 38.26 ? 122 PHE A CD2 1 ATOM 986 C CE1 . PHE A 1 122 ? 16.814 30.196 22.573 1.00 37.38 ? 122 PHE A CE1 1 ATOM 987 C CE2 . PHE A 1 122 ? 16.640 32.371 23.587 1.00 38.04 ? 122 PHE A CE2 1 ATOM 988 C CZ . PHE A 1 122 ? 16.042 31.285 22.955 1.00 37.58 ? 122 PHE A CZ 1 ATOM 989 N N . ALA A 1 123 ? 22.823 33.454 23.186 1.00 43.80 ? 123 ALA A N 1 ATOM 990 C CA . ALA A 1 123 ? 24.150 33.873 23.613 1.00 45.04 ? 123 ALA A CA 1 ATOM 991 C C . ALA A 1 123 ? 24.125 35.288 24.158 1.00 46.22 ? 123 ALA A C 1 ATOM 992 O O . ALA A 1 123 ? 23.389 36.152 23.655 1.00 46.38 ? 123 ALA A O 1 ATOM 993 C CB . ALA A 1 123 ? 25.149 33.757 22.468 1.00 44.76 ? 123 ALA A CB 1 ATOM 994 N N . HIS A 1 124 ? 24.896 35.489 25.228 1.00 47.72 ? 124 HIS A N 1 ATOM 995 C CA . HIS A 1 124 ? 25.223 36.820 25.736 1.00 49.26 ? 124 HIS A CA 1 ATOM 996 C C . HIS A 1 124 ? 26.640 36.813 26.290 1.00 50.20 ? 124 HIS A C 1 ATOM 997 O O . HIS A 1 124 ? 26.932 36.081 27.232 1.00 50.23 ? 124 HIS A O 1 ATOM 998 C CB . HIS A 1 124 ? 24.232 37.307 26.796 1.00 49.29 ? 124 HIS A CB 1 ATOM 999 C CG . HIS A 1 124 ? 24.236 38.795 26.976 1.00 50.12 ? 124 HIS A CG 1 ATOM 1000 N ND1 . HIS A 1 124 ? 25.035 39.434 27.901 1.00 50.15 ? 124 HIS A ND1 1 ATOM 1001 C CD2 . HIS A 1 124 ? 23.548 39.772 26.336 1.00 50.60 ? 124 HIS A CD2 1 ATOM 1002 C CE1 . HIS A 1 124 ? 24.828 40.737 27.833 1.00 49.84 ? 124 HIS A CE1 1 ATOM 1003 N NE2 . HIS A 1 124 ? 23.932 40.969 26.891 1.00 50.30 ? 124 HIS A NE2 1 ATOM 1004 N N . PRO A 1 125 ? 27.532 37.622 25.692 1.00 51.39 ? 125 PRO A N 1 ATOM 1005 C CA . PRO A 1 125 ? 27.215 38.519 24.576 1.00 52.30 ? 125 PRO A CA 1 ATOM 1006 C C . PRO A 1 125 ? 27.104 37.804 23.219 1.00 53.27 ? 125 PRO A C 1 ATOM 1007 O O . PRO A 1 125 ? 27.405 36.604 23.118 1.00 53.08 ? 125 PRO A O 1 ATOM 1008 C CB . PRO A 1 125 ? 28.393 39.496 24.577 1.00 52.31 ? 125 PRO A CB 1 ATOM 1009 C CG . PRO A 1 125 ? 29.541 38.684 25.085 1.00 51.99 ? 125 PRO A CG 1 ATOM 1010 C CD . PRO A 1 125 ? 28.956 37.697 26.074 1.00 51.39 ? 125 PRO A CD 1 ATOM 1011 N N . THR A 1 126 ? 26.655 38.554 22.209 1.00 54.49 ? 126 THR A N 1 ATOM 1012 C CA . THR A 1 126 ? 26.542 38.090 20.825 1.00 55.82 ? 126 THR A CA 1 ATOM 1013 C C . THR A 1 126 ? 27.827 37.402 20.370 1.00 56.79 ? 126 THR A C 1 ATOM 1014 O O . THR A 1 126 ? 28.888 38.023 20.373 1.00 56.66 ? 126 THR A O 1 ATOM 1015 C CB . THR A 1 126 ? 26.225 39.276 19.871 1.00 55.82 ? 126 THR A CB 1 ATOM 1016 O OG1 . THR A 1 126 ? 24.988 39.891 20.257 1.00 55.60 ? 126 THR A OG1 1 ATOM 1017 C CG2 . THR A 1 126 ? 26.137 38.809 18.413 1.00 55.96 ? 126 THR A CG2 1 ATOM 1018 N N . PRO A 1 127 ? 27.734 36.117 19.971 1.00 58.01 ? 127 PRO A N 1 ATOM 1019 C CA . PRO A 1 127 ? 28.941 35.340 19.669 1.00 59.06 ? 127 PRO A CA 1 ATOM 1020 C C . PRO A 1 127 ? 29.649 35.814 18.402 1.00 60.22 ? 127 PRO A C 1 ATOM 1021 O O . PRO A 1 127 ? 29.045 36.482 17.556 1.00 60.25 ? 127 PRO A O 1 ATOM 1022 C CB . PRO A 1 127 ? 28.417 33.912 19.505 1.00 58.83 ? 127 PRO A CB 1 ATOM 1023 C CG . PRO A 1 127 ? 27.004 34.068 19.115 1.00 58.55 ? 127 PRO A CG 1 ATOM 1024 C CD . PRO A 1 127 ? 26.502 35.375 19.654 1.00 57.99 ? 127 PRO A CD 1 ATOM 1025 N N . ARG A 1 128 ? 30.931 35.475 18.296 1.00 61.62 ? 128 ARG A N 1 ATOM 1026 C CA . ARG A 1 128 ? 31.774 35.927 17.194 1.00 62.92 ? 128 ARG A CA 1 ATOM 1027 C C . ARG A 1 128 ? 31.414 35.195 15.901 1.00 63.53 ? 128 ARG A C 1 ATOM 1028 O O . ARG A 1 128 ? 31.131 33.993 15.933 1.00 63.64 ? 128 ARG A O 1 ATOM 1029 C CB . ARG A 1 128 ? 33.256 35.707 17.526 1.00 63.07 ? 128 ARG A CB 1 ATOM 1030 C CG . ARG A 1 128 ? 33.670 36.171 18.918 1.00 64.19 ? 128 ARG A CG 1 ATOM 1031 C CD . ARG A 1 128 ? 35.092 36.710 18.927 1.00 66.38 ? 128 ARG A CD 1 ATOM 1032 N NE . ARG A 1 128 ? 35.230 37.863 18.034 1.00 67.95 ? 128 ARG A NE 1 ATOM 1033 C CZ . ARG A 1 128 ? 36.303 38.650 17.964 1.00 68.67 ? 128 ARG A CZ 1 ATOM 1034 N NH1 . ARG A 1 128 ? 37.361 38.426 18.740 1.00 68.79 ? 128 ARG A NH1 1 ATOM 1035 N NH2 . ARG A 1 128 ? 36.312 39.671 17.115 1.00 68.67 ? 128 ARG A NH2 1 ATOM 1036 N N . PRO A 1 129 ? 31.414 35.920 14.760 1.00 64.16 ? 129 PRO A N 1 ATOM 1037 C CA . PRO A 1 129 ? 31.194 35.268 13.470 1.00 64.56 ? 129 PRO A CA 1 ATOM 1038 C C . PRO A 1 129 ? 32.181 34.120 13.299 1.00 64.97 ? 129 PRO A C 1 ATOM 1039 O O . PRO A 1 129 ? 33.377 34.310 13.530 1.00 65.23 ? 129 PRO A O 1 ATOM 1040 C CB . PRO A 1 129 ? 31.500 36.380 12.462 1.00 64.58 ? 129 PRO A CB 1 ATOM 1041 C CG . PRO A 1 129 ? 31.208 37.647 13.197 1.00 64.46 ? 129 PRO A CG 1 ATOM 1042 C CD . PRO A 1 129 ? 31.596 37.380 14.621 1.00 64.17 ? 129 PRO A CD 1 ATOM 1043 N N . SER A 1 130 ? 31.683 32.937 12.939 1.00 65.31 ? 130 SER A N 1 ATOM 1044 C CA . SER A 1 130 ? 32.550 31.777 12.706 1.00 65.66 ? 130 SER A CA 1 ATOM 1045 C C . SER A 1 130 ? 32.516 31.347 11.238 1.00 65.89 ? 130 SER A C 1 ATOM 1046 O O . SER A 1 130 ? 32.137 32.131 10.361 1.00 65.78 ? 130 SER A O 1 ATOM 1047 C CB . SER A 1 130 ? 32.177 30.612 13.632 1.00 65.56 ? 130 SER A CB 1 ATOM 1048 O OG . SER A 1 130 ? 31.006 29.957 13.184 1.00 65.41 ? 130 SER A OG 1 ATOM 1049 N N . GLU A 1 131 ? 32.916 30.105 10.979 1.00 66.25 ? 131 GLU A N 1 ATOM 1050 C CA . GLU A 1 131 ? 32.942 29.567 9.618 1.00 66.69 ? 131 GLU A CA 1 ATOM 1051 C C . GLU A 1 131 ? 31.536 29.330 9.043 1.00 66.47 ? 131 GLU A C 1 ATOM 1052 O O . GLU A 1 131 ? 31.255 29.707 7.903 1.00 66.64 ? 131 GLU A O 1 ATOM 1053 C CB . GLU A 1 131 ? 33.816 28.298 9.550 1.00 66.93 ? 131 GLU A CB 1 ATOM 1054 C CG . GLU A 1 131 ? 33.601 27.381 8.323 1.00 68.41 ? 131 GLU A CG 1 ATOM 1055 C CD . GLU A 1 131 ? 33.904 28.036 6.962 1.00 70.38 ? 131 GLU A CD 1 ATOM 1056 O OE1 . GLU A 1 131 ? 33.975 27.288 5.957 1.00 70.79 ? 131 GLU A OE1 1 ATOM 1057 O OE2 . GLU A 1 131 ? 34.061 29.281 6.885 1.00 70.99 ? 131 GLU A OE2 1 ATOM 1058 N N . LYS A 1 132 ? 30.664 28.719 9.841 1.00 66.13 ? 132 LYS A N 1 ATOM 1059 C CA . LYS A 1 132 ? 29.321 28.333 9.397 1.00 65.76 ? 132 LYS A CA 1 ATOM 1060 C C . LYS A 1 132 ? 28.287 29.468 9.474 1.00 65.17 ? 132 LYS A C 1 ATOM 1061 O O . LYS A 1 132 ? 27.151 29.320 9.003 1.00 65.26 ? 132 LYS A O 1 ATOM 1062 C CB . LYS A 1 132 ? 28.839 27.129 10.213 1.00 65.98 ? 132 LYS A CB 1 ATOM 1063 C CG . LYS A 1 132 ? 29.474 25.788 9.837 1.00 66.74 ? 132 LYS A CG 1 ATOM 1064 C CD . LYS A 1 132 ? 28.667 25.090 8.748 1.00 67.79 ? 132 LYS A CD 1 ATOM 1065 C CE . LYS A 1 132 ? 28.704 23.581 8.909 1.00 67.90 ? 132 LYS A CE 1 ATOM 1066 N NZ . LYS A 1 132 ? 27.525 22.950 8.246 1.00 68.04 ? 132 LYS A NZ 1 ATOM 1067 N N . CYS A 1 133 ? 28.684 30.589 10.075 1.00 64.30 ? 133 CYS A N 1 ATOM 1068 C CA . CYS A 1 133 ? 27.810 31.753 10.250 1.00 63.28 ? 133 CYS A CA 1 ATOM 1069 C C . CYS A 1 133 ? 28.649 33.025 10.229 1.00 63.04 ? 133 CYS A C 1 ATOM 1070 O O . CYS A 1 133 ? 29.480 33.247 11.114 1.00 63.24 ? 133 CYS A O 1 ATOM 1071 C CB . CYS A 1 133 ? 27.035 31.651 11.571 1.00 62.89 ? 133 CYS A CB 1 ATOM 1072 S SG . CYS A 1 133 ? 25.905 33.032 11.920 1.00 61.33 ? 133 CYS A SG 1 ATOM 1073 N N . SER A 1 134 ? 28.436 33.857 9.216 1.00 62.48 ? 134 SER A N 1 ATOM 1074 C CA . SER A 1 134 ? 29.237 35.068 9.061 1.00 61.99 ? 134 SER A CA 1 ATOM 1075 C C . SER A 1 134 ? 28.730 36.255 9.898 1.00 61.54 ? 134 SER A C 1 ATOM 1076 O O . SER A 1 134 ? 29.444 37.250 10.048 1.00 61.57 ? 134 SER A O 1 ATOM 1077 C CB . SER A 1 134 ? 29.393 35.441 7.580 1.00 61.95 ? 134 SER A CB 1 ATOM 1078 O OG . SER A 1 134 ? 28.137 35.554 6.937 1.00 62.09 ? 134 SER A OG 1 ATOM 1079 N N . LYS A 1 135 ? 27.515 36.149 10.444 1.00 60.84 ? 135 LYS A N 1 ATOM 1080 C CA . LYS A 1 135 ? 26.977 37.172 11.356 1.00 60.13 ? 135 LYS A CA 1 ATOM 1081 C C . LYS A 1 135 ? 25.709 36.745 12.095 1.00 59.37 ? 135 LYS A C 1 ATOM 1082 O O . LYS A 1 135 ? 24.659 36.536 11.485 1.00 59.27 ? 135 LYS A O 1 ATOM 1083 C CB . LYS A 1 135 ? 26.746 38.513 10.629 1.00 60.36 ? 135 LYS A CB 1 ATOM 1084 C CG . LYS A 1 135 ? 26.152 39.650 11.489 1.00 61.05 ? 135 LYS A CG 1 ATOM 1085 C CD . LYS A 1 135 ? 26.916 39.887 12.805 1.00 63.00 ? 135 LYS A CD 1 ATOM 1086 C CE . LYS A 1 135 ? 28.227 40.653 12.614 1.00 63.47 ? 135 LYS A CE 1 ATOM 1087 N NZ . LYS A 1 135 ? 27.990 42.116 12.459 1.00 63.75 ? 135 LYS A NZ 1 ATOM 1088 N N . TRP A 1 136 ? 25.819 36.638 13.416 1.00 58.40 ? 136 TRP A N 1 ATOM 1089 C CA . TRP A 1 136 ? 24.669 36.383 14.270 1.00 57.47 ? 136 TRP A CA 1 ATOM 1090 C C . TRP A 1 136 ? 23.904 37.669 14.515 1.00 57.45 ? 136 TRP A C 1 ATOM 1091 O O . TRP A 1 136 ? 24.494 38.686 14.875 1.00 57.43 ? 136 TRP A O 1 ATOM 1092 C CB . TRP A 1 136 ? 25.114 35.790 15.607 1.00 57.21 ? 136 TRP A CB 1 ATOM 1093 C CG . TRP A 1 136 ? 25.580 34.374 15.504 1.00 55.34 ? 136 TRP A CG 1 ATOM 1094 C CD1 . TRP A 1 136 ? 26.871 33.939 15.471 1.00 53.78 ? 136 TRP A CD1 1 ATOM 1095 C CD2 . TRP A 1 136 ? 24.756 33.206 15.407 1.00 53.23 ? 136 TRP A CD2 1 ATOM 1096 N NE1 . TRP A 1 136 ? 26.904 32.572 15.365 1.00 53.19 ? 136 TRP A NE1 1 ATOM 1097 C CE2 . TRP A 1 136 ? 25.620 32.096 15.323 1.00 52.58 ? 136 TRP A CE2 1 ATOM 1098 C CE3 . TRP A 1 136 ? 23.371 32.990 15.386 1.00 52.33 ? 136 TRP A CE3 1 ATOM 1099 C CZ2 . TRP A 1 136 ? 25.146 30.785 15.214 1.00 51.55 ? 136 TRP A CZ2 1 ATOM 1100 C CZ3 . TRP A 1 136 ? 22.900 31.687 15.279 1.00 51.26 ? 136 TRP A CZ3 1 ATOM 1101 C CH2 . TRP A 1 136 ? 23.787 30.603 15.194 1.00 51.26 ? 136 TRP A CH2 1 ATOM 1102 N N . ILE A 1 137 ? 22.592 37.620 14.314 1.00 57.40 ? 137 ILE A N 1 ATOM 1103 C CA . ILE A 1 137 ? 21.728 38.766 14.571 1.00 57.51 ? 137 ILE A CA 1 ATOM 1104 C C . ILE A 1 137 ? 20.668 38.406 15.611 1.00 57.77 ? 137 ILE A C 1 ATOM 1105 O O . ILE A 1 137 ? 19.958 37.414 15.467 1.00 57.76 ? 137 ILE A O 1 ATOM 1106 C CB . ILE A 1 137 ? 21.066 39.313 13.268 1.00 57.40 ? 137 ILE A CB 1 ATOM 1107 C CG1 . ILE A 1 137 ? 22.116 39.914 12.331 1.00 57.37 ? 137 ILE A CG1 1 ATOM 1108 C CG2 . ILE A 1 137 ? 20.018 40.373 13.574 1.00 57.22 ? 137 ILE A CG2 1 ATOM 1109 C CD1 . ILE A 1 137 ? 22.508 39.011 11.183 1.00 57.95 ? 137 ILE A CD1 1 ATOM 1110 N N . LEU A 1 138 ? 20.592 39.222 16.661 1.00 58.16 ? 138 LEU A N 1 ATOM 1111 C CA . LEU A 1 138 ? 19.577 39.112 17.704 1.00 58.72 ? 138 LEU A CA 1 ATOM 1112 C C . LEU A 1 138 ? 18.179 39.197 17.087 1.00 59.17 ? 138 LEU A C 1 ATOM 1113 O O . LEU A 1 138 ? 17.938 40.019 16.197 1.00 59.31 ? 138 LEU A O 1 ATOM 1114 C CB . LEU A 1 138 ? 19.786 40.234 18.736 1.00 58.76 ? 138 LEU A CB 1 ATOM 1115 C CG . LEU A 1 138 ? 19.206 40.197 20.160 1.00 58.86 ? 138 LEU A CG 1 ATOM 1116 C CD1 . LEU A 1 138 ? 19.748 39.030 20.974 1.00 58.36 ? 138 LEU A CD1 1 ATOM 1117 C CD2 . LEU A 1 138 ? 19.491 41.515 20.882 1.00 58.35 ? 138 LEU A CD2 1 ATOM 1118 N N . LEU A 1 139 ? 17.273 38.335 17.545 1.00 59.70 ? 139 LEU A N 1 ATOM 1119 C CA . LEU A 1 139 ? 15.906 38.288 17.018 1.00 60.19 ? 139 LEU A CA 1 ATOM 1120 C C . LEU A 1 139 ? 15.110 39.552 17.319 1.00 60.71 ? 139 LEU A C 1 ATOM 1121 O O . LEU A 1 139 ? 14.347 40.022 16.469 1.00 60.76 ? 139 LEU A O 1 ATOM 1122 C CB . LEU A 1 139 ? 15.140 37.061 17.536 1.00 60.05 ? 139 LEU A CB 1 ATOM 1123 C CG . LEU A 1 139 ? 14.951 35.814 16.658 1.00 59.76 ? 139 LEU A CG 1 ATOM 1124 C CD1 . LEU A 1 139 ? 14.496 36.147 15.233 1.00 59.37 ? 139 LEU A CD1 1 ATOM 1125 C CD2 . LEU A 1 139 ? 16.200 34.951 16.632 1.00 59.79 ? 139 LEU A CD2 1 ATOM 1126 N N . GLU A 1 140 ? 15.285 40.096 18.523 1.00 61.24 ? 140 GLU A N 1 ATOM 1127 C CA . GLU A 1 140 ? 14.555 41.299 18.926 1.00 61.97 ? 140 GLU A CA 1 ATOM 1128 C C . GLU A 1 140 ? 14.864 42.491 18.019 1.00 62.15 ? 140 GLU A C 1 ATOM 1129 O O . GLU A 1 140 ? 14.013 43.363 17.828 1.00 62.34 ? 140 GLU A O 1 ATOM 1130 C CB . GLU A 1 140 ? 14.774 41.622 20.410 1.00 62.00 ? 140 GLU A CB 1 ATOM 1131 C CG . GLU A 1 140 ? 13.880 40.775 21.324 1.00 63.04 ? 140 GLU A CG 1 ATOM 1132 C CD . GLU A 1 140 ? 14.153 40.964 22.811 1.00 64.41 ? 140 GLU A CD 1 ATOM 1133 O OE1 . GLU A 1 140 ? 14.431 42.112 23.235 1.00 64.52 ? 140 GLU A OE1 1 ATOM 1134 O OE2 . GLU A 1 140 ? 14.069 39.955 23.557 1.00 64.32 ? 140 GLU A OE2 1 ATOM 1135 N N . ASP A 1 141 ? 16.070 42.502 17.448 1.00 62.35 ? 141 ASP A N 1 ATOM 1136 C CA . ASP A 1 141 ? 16.445 43.473 16.419 1.00 62.56 ? 141 ASP A CA 1 ATOM 1137 C C . ASP A 1 141 ? 15.687 43.171 15.132 1.00 62.64 ? 141 ASP A C 1 ATOM 1138 O O . ASP A 1 141 ? 14.885 43.982 14.669 1.00 62.90 ? 141 ASP A O 1 ATOM 1139 C CB . ASP A 1 141 ? 17.954 43.428 16.141 1.00 62.53 ? 141 ASP A CB 1 ATOM 1140 C CG . ASP A 1 141 ? 18.792 43.893 17.322 1.00 62.74 ? 141 ASP A CG 1 ATOM 1141 O OD1 . ASP A 1 141 ? 18.241 44.511 18.263 1.00 62.82 ? 141 ASP A OD1 1 ATOM 1142 O OD2 . ASP A 1 141 ? 20.018 43.640 17.298 1.00 62.90 ? 141 ASP A OD2 1 ATOM 1143 N N . TYR A 1 142 ? 15.954 41.992 14.576 1.00 62.58 ? 142 TYR A N 1 ATOM 1144 C CA . TYR A 1 142 ? 15.326 41.498 13.359 1.00 62.52 ? 142 TYR A CA 1 ATOM 1145 C C . TYR A 1 142 ? 13.824 41.790 13.303 1.00 62.51 ? 142 TYR A C 1 ATOM 1146 O O . TYR A 1 142 ? 13.328 42.295 12.297 1.00 62.45 ? 142 TYR A O 1 ATOM 1147 C CB . TYR A 1 142 ? 15.554 39.994 13.280 1.00 62.52 ? 142 TYR A CB 1 ATOM 1148 C CG . TYR A 1 142 ? 15.939 39.478 11.923 1.00 62.92 ? 142 TYR A CG 1 ATOM 1149 C CD1 . TYR A 1 142 ? 17.263 39.148 11.639 1.00 63.43 ? 142 TYR A CD1 1 ATOM 1150 C CD2 . TYR A 1 142 ? 14.981 39.293 10.926 1.00 63.63 ? 142 TYR A CD2 1 ATOM 1151 C CE1 . TYR A 1 142 ? 17.633 38.653 10.390 1.00 63.88 ? 142 TYR A CE1 1 ATOM 1152 C CE2 . TYR A 1 142 ? 15.336 38.799 9.670 1.00 64.19 ? 142 TYR A CE2 1 ATOM 1153 C CZ . TYR A 1 142 ? 16.665 38.482 9.408 1.00 64.29 ? 142 TYR A CZ 1 ATOM 1154 O OH . TYR A 1 142 ? 17.023 37.994 8.169 1.00 64.44 ? 142 TYR A OH 1 ATOM 1155 N N . ARG A 1 143 ? 13.118 41.483 14.393 1.00 62.60 ? 143 ARG A N 1 ATOM 1156 C CA . ARG A 1 143 ? 11.656 41.634 14.479 1.00 62.66 ? 143 ARG A CA 1 ATOM 1157 C C . ARG A 1 143 ? 11.150 43.074 14.385 1.00 62.93 ? 143 ARG A C 1 ATOM 1158 O O . ARG A 1 143 ? 9.974 43.303 14.079 1.00 63.03 ? 143 ARG A O 1 ATOM 1159 C CB . ARG A 1 143 ? 11.106 40.978 15.753 1.00 62.58 ? 143 ARG A CB 1 ATOM 1160 C CG . ARG A 1 143 ? 10.753 39.515 15.582 1.00 61.92 ? 143 ARG A CG 1 ATOM 1161 C CD . ARG A 1 143 ? 9.915 38.993 16.737 1.00 61.02 ? 143 ARG A CD 1 ATOM 1162 N NE . ARG A 1 143 ? 9.528 37.597 16.518 1.00 60.62 ? 143 ARG A NE 1 ATOM 1163 C CZ . ARG A 1 143 ? 10.244 36.539 16.898 1.00 59.80 ? 143 ARG A CZ 1 ATOM 1164 N NH1 . ARG A 1 143 ? 11.400 36.689 17.538 1.00 58.86 ? 143 ARG A NH1 1 ATOM 1165 N NH2 . ARG A 1 143 ? 9.797 35.320 16.636 1.00 59.50 ? 143 ARG A NH2 1 ATOM 1166 N N . LYS A 1 144 ? 12.028 44.036 14.662 1.00 63.10 ? 144 LYS A N 1 ATOM 1167 C CA . LYS A 1 144 ? 11.700 45.450 14.484 1.00 63.15 ? 144 LYS A CA 1 ATOM 1168 C C . LYS A 1 144 ? 11.978 45.876 13.037 1.00 63.28 ? 144 LYS A C 1 ATOM 1169 O O . LYS A 1 144 ? 11.246 46.693 12.476 1.00 63.28 ? 144 LYS A O 1 ATOM 1170 C CB . LYS A 1 144 ? 12.468 46.324 15.485 1.00 63.11 ? 144 LYS A CB 1 ATOM 1171 C CG . LYS A 1 144 ? 12.147 46.029 16.961 1.00 62.85 ? 144 LYS A CG 1 ATOM 1172 C CD . LYS A 1 144 ? 12.655 47.119 17.906 1.00 62.61 ? 144 LYS A CD 1 ATOM 1173 C CE . LYS A 1 144 ? 14.175 47.103 18.061 1.00 62.52 ? 144 LYS A CE 1 ATOM 1174 N NZ . LYS A 1 144 ? 14.640 46.011 18.954 1.00 62.38 ? 144 LYS A NZ 1 ATOM 1175 N N . ARG A 1 145 ? 13.016 45.282 12.439 1.00 63.37 ? 145 ARG A N 1 ATOM 1176 C CA . ARG A 1 145 ? 13.463 45.606 11.078 1.00 63.45 ? 145 ARG A CA 1 ATOM 1177 C C . ARG A 1 145 ? 12.661 44.932 9.955 1.00 63.32 ? 145 ARG A C 1 ATOM 1178 O O . ARG A 1 145 ? 13.183 44.742 8.849 1.00 63.36 ? 145 ARG A O 1 ATOM 1179 C CB . ARG A 1 145 ? 14.952 45.271 10.905 1.00 63.57 ? 145 ARG A CB 1 ATOM 1180 C CG . ARG A 1 145 ? 15.906 46.169 11.678 1.00 64.88 ? 145 ARG A CG 1 ATOM 1181 C CD . ARG A 1 145 ? 17.267 46.245 10.995 1.00 66.78 ? 145 ARG A CD 1 ATOM 1182 N NE . ARG A 1 145 ? 18.363 46.335 11.961 1.00 68.92 ? 145 ARG A NE 1 ATOM 1183 C CZ . ARG A 1 145 ? 19.129 45.307 12.335 1.00 70.22 ? 145 ARG A CZ 1 ATOM 1184 N NH1 . ARG A 1 145 ? 18.935 44.094 11.820 1.00 70.39 ? 145 ARG A NH1 1 ATOM 1185 N NH2 . ARG A 1 145 ? 20.100 45.489 13.226 1.00 70.24 ? 145 ARG A NH2 1 ATOM 1186 N N . VAL A 1 146 ? 11.410 44.563 10.234 1.00 63.06 ? 146 VAL A N 1 ATOM 1187 C CA . VAL A 1 146 ? 10.533 43.943 9.223 1.00 62.71 ? 146 VAL A CA 1 ATOM 1188 C C . VAL A 1 146 ? 9.183 44.655 9.171 1.00 62.57 ? 146 VAL A C 1 ATOM 1189 O O . VAL A 1 146 ? 8.768 45.263 10.164 1.00 62.54 ? 146 VAL A O 1 ATOM 1190 C CB . VAL A 1 146 ? 10.326 42.399 9.439 1.00 62.63 ? 146 VAL A CB 1 ATOM 1191 C CG1 . VAL A 1 146 ? 11.622 41.631 9.198 1.00 62.25 ? 146 VAL A CG1 1 ATOM 1192 C CG2 . VAL A 1 146 ? 9.738 42.089 10.823 1.00 62.34 ? 146 VAL A CG2 1 ATOM 1193 N N . GLN A 1 147 ? 8.505 44.577 8.023 1.00 62.42 ? 147 GLN A N 1 ATOM 1194 C CA . GLN A 1 147 ? 7.215 45.263 7.841 1.00 62.27 ? 147 GLN A CA 1 ATOM 1195 C C . GLN A 1 147 ? 6.061 44.544 8.552 1.00 61.89 ? 147 GLN A C 1 ATOM 1196 O O . GLN A 1 147 ? 5.371 45.147 9.381 1.00 61.91 ? 147 GLN A O 1 ATOM 1197 C CB . GLN A 1 147 ? 6.904 45.497 6.353 1.00 62.40 ? 147 GLN A CB 1 ATOM 1198 C CG . GLN A 1 147 ? 5.926 46.664 6.082 1.00 63.28 ? 147 GLN A CG 1 ATOM 1199 C CD . GLN A 1 147 ? 6.560 48.060 6.248 1.00 64.10 ? 147 GLN A CD 1 ATOM 1200 O OE1 . GLN A 1 147 ? 6.472 48.671 7.318 1.00 64.22 ? 147 GLN A OE1 1 ATOM 1201 N NE2 . GLN A 1 147 ? 7.193 48.563 5.186 1.00 63.69 ? 147 GLN A NE2 1 ATOM 1202 N N . ASN A 1 148 ? 5.858 43.264 8.236 1.00 61.39 ? 148 ASN A N 1 ATOM 1203 C CA . ASN A 1 148 ? 4.845 42.459 8.927 1.00 60.79 ? 148 ASN A CA 1 ATOM 1204 C C . ASN A 1 148 ? 5.502 41.394 9.816 1.00 60.37 ? 148 ASN A C 1 ATOM 1205 O O . ASN A 1 148 ? 6.074 40.415 9.320 1.00 60.32 ? 148 ASN A O 1 ATOM 1206 C CB . ASN A 1 148 ? 3.851 41.844 7.927 1.00 60.76 ? 148 ASN A CB 1 ATOM 1207 C CG . ASN A 1 148 ? 2.524 41.432 8.576 1.00 60.70 ? 148 ASN A CG 1 ATOM 1208 O OD1 . ASN A 1 148 ? 2.441 41.235 9.791 1.00 60.33 ? 148 ASN A OD1 1 ATOM 1209 N ND2 . ASN A 1 148 ? 1.482 41.294 7.756 1.00 60.26 ? 148 ASN A ND2 1 ATOM 1210 N N . VAL A 1 149 ? 5.422 41.608 11.129 1.00 59.77 ? 149 VAL A N 1 ATOM 1211 C CA . VAL A 1 149 ? 6.089 40.750 12.117 1.00 59.14 ? 149 VAL A CA 1 ATOM 1212 C C . VAL A 1 149 ? 5.395 39.394 12.284 1.00 58.73 ? 149 VAL A C 1 ATOM 1213 O O . VAL A 1 149 ? 6.066 38.370 12.440 1.00 58.73 ? 149 VAL A O 1 ATOM 1214 C CB . VAL A 1 149 ? 6.282 41.471 13.497 1.00 59.19 ? 149 VAL A CB 1 ATOM 1215 C CG1 . VAL A 1 149 ? 4.958 41.607 14.264 1.00 59.19 ? 149 VAL A CG1 1 ATOM 1216 C CG2 . VAL A 1 149 ? 7.329 40.756 14.346 1.00 59.02 ? 149 VAL A CG2 1 ATOM 1217 N N . THR A 1 150 ? 4.062 39.389 12.237 1.00 58.00 ? 150 THR A N 1 ATOM 1218 C CA . THR A 1 150 ? 3.296 38.146 12.353 1.00 57.35 ? 150 THR A CA 1 ATOM 1219 C C . THR A 1 150 ? 3.295 37.365 11.036 1.00 56.75 ? 150 THR A C 1 ATOM 1220 O O . THR A 1 150 ? 2.851 36.213 10.987 1.00 56.76 ? 150 THR A O 1 ATOM 1221 C CB . THR A 1 150 ? 1.850 38.391 12.826 1.00 57.46 ? 150 THR A CB 1 ATOM 1222 O OG1 . THR A 1 150 ? 1.241 39.390 11.998 1.00 57.66 ? 150 THR A OG1 1 ATOM 1223 C CG2 . THR A 1 150 ? 1.824 38.836 14.298 1.00 57.29 ? 150 THR A CG2 1 ATOM 1224 N N . GLU A 1 151 ? 3.788 38.003 9.975 1.00 55.92 ? 151 GLU A N 1 ATOM 1225 C CA . GLU A 1 151 ? 4.062 37.320 8.714 1.00 55.00 ? 151 GLU A CA 1 ATOM 1226 C C . GLU A 1 151 ? 5.430 36.680 8.819 1.00 53.89 ? 151 GLU A C 1 ATOM 1227 O O . GLU A 1 151 ? 5.633 35.551 8.378 1.00 54.01 ? 151 GLU A O 1 ATOM 1228 C CB . GLU A 1 151 ? 4.006 38.298 7.529 1.00 55.23 ? 151 GLU A CB 1 ATOM 1229 C CG . GLU A 1 151 ? 4.619 37.781 6.216 1.00 56.40 ? 151 GLU A CG 1 ATOM 1230 C CD . GLU A 1 151 ? 4.050 36.431 5.769 1.00 58.20 ? 151 GLU A CD 1 ATOM 1231 O OE1 . GLU A 1 151 ? 2.834 36.192 5.968 1.00 58.89 ? 151 GLU A OE1 1 ATOM 1232 O OE2 . GLU A 1 151 ? 4.823 35.606 5.222 1.00 58.55 ? 151 GLU A OE2 1 ATOM 1233 N N . PHE A 1 152 ? 6.361 37.419 9.412 1.00 52.67 ? 152 PHE A N 1 ATOM 1234 C CA . PHE A 1 152 ? 7.709 36.930 9.682 1.00 51.39 ? 152 PHE A CA 1 ATOM 1235 C C . PHE A 1 152 ? 7.679 35.734 10.633 1.00 50.52 ? 152 PHE A C 1 ATOM 1236 O O . PHE A 1 152 ? 8.422 34.769 10.453 1.00 50.32 ? 152 PHE A O 1 ATOM 1237 C CB . PHE A 1 152 ? 8.565 38.058 10.268 1.00 51.37 ? 152 PHE A CB 1 ATOM 1238 C CG . PHE A 1 152 ? 9.862 37.593 10.861 1.00 51.14 ? 152 PHE A CG 1 ATOM 1239 C CD1 . PHE A 1 152 ? 10.941 37.258 10.039 1.00 51.00 ? 152 PHE A CD1 1 ATOM 1240 C CD2 . PHE A 1 152 ? 10.008 37.486 12.243 1.00 50.83 ? 152 PHE A CD2 1 ATOM 1241 C CE1 . PHE A 1 152 ? 12.148 36.822 10.586 1.00 50.61 ? 152 PHE A CE1 1 ATOM 1242 C CE2 . PHE A 1 152 ? 11.210 37.054 12.804 1.00 50.52 ? 152 PHE A CE2 1 ATOM 1243 C CZ . PHE A 1 152 ? 12.283 36.722 11.973 1.00 50.89 ? 152 PHE A CZ 1 ATOM 1244 N N . ASP A 1 153 ? 6.816 35.812 11.643 1.00 49.44 ? 153 ASP A N 1 ATOM 1245 C CA . ASP A 1 153 ? 6.645 34.731 12.607 1.00 48.47 ? 153 ASP A CA 1 ATOM 1246 C C . ASP A 1 153 ? 6.068 33.474 11.951 1.00 48.19 ? 153 ASP A C 1 ATOM 1247 O O . ASP A 1 153 ? 6.549 32.366 12.205 1.00 48.05 ? 153 ASP A O 1 ATOM 1248 C CB . ASP A 1 153 ? 5.771 35.184 13.778 1.00 48.08 ? 153 ASP A CB 1 ATOM 1249 C CG . ASP A 1 153 ? 6.513 36.085 14.754 1.00 47.24 ? 153 ASP A CG 1 ATOM 1250 O OD1 . ASP A 1 153 ? 7.725 36.333 14.566 1.00 46.23 ? 153 ASP A OD1 1 ATOM 1251 O OD2 . ASP A 1 153 ? 5.872 36.547 15.723 1.00 46.20 ? 153 ASP A OD2 1 ATOM 1252 N N . ASP A 1 154 ? 5.051 33.654 11.105 1.00 47.70 ? 154 ASP A N 1 ATOM 1253 C CA . ASP A 1 154 ? 4.448 32.551 10.358 1.00 47.30 ? 154 ASP A CA 1 ATOM 1254 C C . ASP A 1 154 ? 5.438 31.867 9.424 1.00 46.42 ? 154 ASP A C 1 ATOM 1255 O O . ASP A 1 154 ? 5.367 30.655 9.225 1.00 46.34 ? 154 ASP A O 1 ATOM 1256 C CB . ASP A 1 154 ? 3.220 33.020 9.572 1.00 47.82 ? 154 ASP A CB 1 ATOM 1257 C CG . ASP A 1 154 ? 1.968 33.126 10.442 1.00 49.92 ? 154 ASP A CG 1 ATOM 1258 O OD1 . ASP A 1 154 ? 1.868 32.397 11.458 1.00 52.21 ? 154 ASP A OD1 1 ATOM 1259 O OD2 . ASP A 1 154 ? 1.075 33.940 10.107 1.00 52.03 ? 154 ASP A OD2 1 ATOM 1260 N N . SER A 1 155 ? 6.365 32.639 8.865 1.00 45.49 ? 155 SER A N 1 ATOM 1261 C CA . SER A 1 155 ? 7.388 32.086 7.978 1.00 44.73 ? 155 SER A CA 1 ATOM 1262 C C . SER A 1 155 ? 8.388 31.237 8.760 1.00 44.12 ? 155 SER A C 1 ATOM 1263 O O . SER A 1 155 ? 9.028 30.344 8.199 1.00 44.02 ? 155 SER A O 1 ATOM 1264 C CB . SER A 1 155 ? 8.104 33.193 7.198 1.00 44.72 ? 155 SER A CB 1 ATOM 1265 O OG . SER A 1 155 ? 8.997 33.914 8.029 1.00 45.18 ? 155 SER A OG 1 ATOM 1266 N N . LEU A 1 156 ? 8.521 31.527 10.054 1.00 43.43 ? 156 LEU A N 1 ATOM 1267 C CA . LEU A 1 156 ? 9.321 30.693 10.952 1.00 42.83 ? 156 LEU A CA 1 ATOM 1268 C C . LEU A 1 156 ? 8.590 29.384 11.271 1.00 42.67 ? 156 LEU A C 1 ATOM 1269 O O . LEU A 1 156 ? 9.209 28.319 11.287 1.00 42.30 ? 156 LEU A O 1 ATOM 1270 C CB . LEU A 1 156 ? 9.675 31.434 12.249 1.00 42.55 ? 156 LEU A CB 1 ATOM 1271 C CG . LEU A 1 156 ? 10.669 32.601 12.240 1.00 42.05 ? 156 LEU A CG 1 ATOM 1272 C CD1 . LEU A 1 156 ? 10.701 33.287 13.607 1.00 40.97 ? 156 LEU A CD1 1 ATOM 1273 C CD2 . LEU A 1 156 ? 12.066 32.154 11.833 1.00 40.87 ? 156 LEU A CD2 1 ATOM 1274 N N . LEU A 1 157 ? 7.279 29.472 11.519 1.00 42.48 ? 157 LEU A N 1 ATOM 1275 C CA . LEU A 1 157 ? 6.457 28.291 11.789 1.00 42.55 ? 157 LEU A CA 1 ATOM 1276 C C . LEU A 1 157 ? 6.427 27.354 10.576 1.00 42.68 ? 157 LEU A C 1 ATOM 1277 O O . LEU A 1 157 ? 6.431 26.133 10.732 1.00 42.69 ? 157 LEU A O 1 ATOM 1278 C CB . LEU A 1 157 ? 5.035 28.687 12.207 1.00 42.45 ? 157 LEU A CB 1 ATOM 1279 N N . ARG A 1 158 ? 6.426 27.932 9.374 1.00 42.90 ? 158 ARG A N 1 ATOM 1280 C CA . ARG A 1 158 ? 6.429 27.159 8.128 1.00 43.02 ? 158 ARG A CA 1 ATOM 1281 C C . ARG A 1 158 ? 7.759 26.470 7.849 1.00 42.71 ? 158 ARG A C 1 ATOM 1282 O O . ARG A 1 158 ? 7.813 25.524 7.066 1.00 42.92 ? 158 ARG A O 1 ATOM 1283 C CB . ARG A 1 158 ? 6.026 28.026 6.927 1.00 43.22 ? 158 ARG A CB 1 ATOM 1284 C CG . ARG A 1 158 ? 4.533 28.329 6.839 1.00 44.78 ? 158 ARG A CG 1 ATOM 1285 C CD . ARG A 1 158 ? 4.144 28.890 5.463 1.00 47.88 ? 158 ARG A CD 1 ATOM 1286 N NE . ARG A 1 158 ? 4.944 30.063 5.108 1.00 50.27 ? 158 ARG A NE 1 ATOM 1287 C CZ . ARG A 1 158 ? 4.655 31.317 5.454 1.00 51.80 ? 158 ARG A CZ 1 ATOM 1288 N NH1 . ARG A 1 158 ? 3.564 31.595 6.163 1.00 52.33 ? 158 ARG A NH1 1 ATOM 1289 N NH2 . ARG A 1 158 ? 5.462 32.304 5.085 1.00 52.30 ? 158 ARG A NH2 1 ATOM 1290 N N . ASN A 1 159 ? 8.827 26.943 8.481 1.00 42.43 ? 159 ASN A N 1 ATOM 1291 C CA . ASN A 1 159 ? 10.135 26.317 8.321 1.00 42.34 ? 159 ASN A CA 1 ATOM 1292 C C . ASN A 1 159 ? 10.405 25.255 9.377 1.00 40.76 ? 159 ASN A C 1 ATOM 1293 O O . ASN A 1 159 ? 11.372 24.500 9.271 1.00 40.81 ? 159 ASN A O 1 ATOM 1294 C CB . ASN A 1 159 ? 11.216 27.363 8.445 1.00 43.40 ? 159 ASN A CB 1 ATOM 1295 C CG . ASN A 1 159 ? 12.184 27.347 7.303 1.00 48.22 ? 159 ASN A CG 1 ATOM 1296 O OD1 . ASN A 1 159 ? 13.251 26.726 7.354 1.00 50.61 ? 159 ASN A OD1 1 ATOM 1297 N ND2 . ASN A 1 159 ? 11.801 28.056 6.251 1.00 55.64 ? 159 ASN A ND2 1 ATOM 1298 N N . PHE A 1 160 ? 9.558 25.216 10.402 1.00 38.95 ? 160 PHE A N 1 ATOM 1299 C CA . PHE A 1 160 ? 9.754 24.340 11.560 1.00 37.20 ? 160 PHE A CA 1 ATOM 1300 C C . PHE A 1 160 ? 8.972 23.033 11.433 1.00 36.21 ? 160 PHE A C 1 ATOM 1301 O O . PHE A 1 160 ? 9.111 22.147 12.270 1.00 36.19 ? 160 PHE A O 1 ATOM 1302 C CB . PHE A 1 160 ? 9.351 25.064 12.858 1.00 36.95 ? 160 PHE A CB 1 ATOM 1303 C CG . PHE A 1 160 ? 10.359 26.077 13.349 1.00 35.85 ? 160 PHE A CG 1 ATOM 1304 C CD1 . PHE A 1 160 ? 11.457 26.458 12.566 1.00 34.98 ? 160 PHE A CD1 1 ATOM 1305 C CD2 . PHE A 1 160 ? 10.186 26.679 14.596 1.00 35.08 ? 160 PHE A CD2 1 ATOM 1306 C CE1 . PHE A 1 160 ? 12.374 27.396 13.030 1.00 34.30 ? 160 PHE A CE1 1 ATOM 1307 C CE2 . PHE A 1 160 ? 11.099 27.625 15.074 1.00 34.12 ? 160 PHE A CE2 1 ATOM 1308 C CZ . PHE A 1 160 ? 12.193 27.988 14.286 1.00 34.49 ? 160 PHE A CZ 1 ATOM 1309 N N . THR A 1 161 ? 8.122 22.931 10.412 1.00 34.84 ? 161 THR A N 1 ATOM 1310 C CA . THR A 1 161 ? 7.390 21.693 10.151 1.00 33.49 ? 161 THR A CA 1 ATOM 1311 C C . THR A 1 161 ? 7.414 21.347 8.668 1.00 32.58 ? 161 THR A C 1 ATOM 1312 O O . THR A 1 161 ? 7.834 22.157 7.828 1.00 32.56 ? 161 THR A O 1 ATOM 1313 C CB . THR A 1 161 ? 5.904 21.705 10.654 1.00 33.57 ? 161 THR A CB 1 ATOM 1314 O OG1 . THR A 1 161 ? 5.063 22.373 9.706 1.00 34.22 ? 161 THR A OG1 1 ATOM 1315 C CG2 . THR A 1 161 ? 5.753 22.348 12.031 1.00 33.19 ? 161 THR A CG2 1 ATOM 1316 N N . LEU A 1 162 ? 6.968 20.133 8.362 1.00 31.23 ? 162 LEU A N 1 ATOM 1317 C CA . LEU A 1 162 ? 6.873 19.654 6.998 1.00 29.73 ? 162 LEU A CA 1 ATOM 1318 C C . LEU A 1 162 ? 5.533 20.013 6.382 1.00 29.53 ? 162 LEU A C 1 ATOM 1319 O O . LEU A 1 162 ? 5.380 19.963 5.165 1.00 28.93 ? 162 LEU A O 1 ATOM 1320 C CB . LEU A 1 162 ? 7.064 18.141 6.971 1.00 29.38 ? 162 LEU A CB 1 ATOM 1321 C CG . LEU A 1 162 ? 8.477 17.616 7.217 1.00 27.92 ? 162 LEU A CG 1 ATOM 1322 C CD1 . LEU A 1 162 ? 8.451 16.114 7.397 1.00 26.10 ? 162 LEU A CD1 1 ATOM 1323 C CD2 . LEU A 1 162 ? 9.407 18.003 6.084 1.00 24.85 ? 162 LEU A CD2 1 ATOM 1324 N N . VAL A 1 163 ? 4.569 20.359 7.237 1.00 29.62 ? 163 VAL A N 1 ATOM 1325 C CA . VAL A 1 163 ? 3.212 20.714 6.817 1.00 29.76 ? 163 VAL A CA 1 ATOM 1326 C C . VAL A 1 163 ? 3.257 21.706 5.662 1.00 30.57 ? 163 VAL A C 1 ATOM 1327 O O . VAL A 1 163 ? 3.996 22.693 5.700 1.00 30.78 ? 163 VAL A O 1 ATOM 1328 C CB . VAL A 1 163 ? 2.353 21.271 7.994 1.00 29.64 ? 163 VAL A CB 1 ATOM 1329 C CG1 . VAL A 1 163 ? 0.925 21.622 7.527 1.00 28.01 ? 163 VAL A CG1 1 ATOM 1330 C CG2 . VAL A 1 163 ? 2.311 20.271 9.140 1.00 28.45 ? 163 VAL A CG2 1 ATOM 1331 N N . THR A 1 164 ? 2.486 21.402 4.625 1.00 31.49 ? 164 THR A N 1 ATOM 1332 C CA . THR A 1 164 ? 2.396 22.229 3.436 1.00 32.59 ? 164 THR A CA 1 ATOM 1333 C C . THR A 1 164 ? 1.177 21.816 2.627 1.00 33.54 ? 164 THR A C 1 ATOM 1334 O O . THR A 1 164 ? 0.687 20.692 2.743 1.00 33.64 ? 164 THR A O 1 ATOM 1335 C CB . THR A 1 164 ? 3.675 22.123 2.545 1.00 32.37 ? 164 THR A CB 1 ATOM 1336 O OG1 . THR A 1 164 ? 3.510 22.910 1.361 1.00 32.89 ? 164 THR A OG1 1 ATOM 1337 C CG2 . THR A 1 164 ? 3.961 20.691 2.136 1.00 31.93 ? 164 THR A CG2 1 ATOM 1338 N N . GLN A 1 165 ? 0.683 22.739 1.814 1.00 34.87 ? 165 GLN A N 1 ATOM 1339 C CA . GLN A 1 165 ? -0.242 22.389 0.756 1.00 36.08 ? 165 GLN A CA 1 ATOM 1340 C C . GLN A 1 165 ? 0.551 21.677 -0.328 1.00 36.27 ? 165 GLN A C 1 ATOM 1341 O O . GLN A 1 165 ? 1.753 21.899 -0.477 1.00 36.38 ? 165 GLN A O 1 ATOM 1342 C CB . GLN A 1 165 ? -0.868 23.646 0.187 1.00 36.43 ? 165 GLN A CB 1 ATOM 1343 C CG . GLN A 1 165 ? -2.017 24.178 0.997 1.00 39.32 ? 165 GLN A CG 1 ATOM 1344 C CD . GLN A 1 165 ? -2.737 25.292 0.266 1.00 43.74 ? 165 GLN A CD 1 ATOM 1345 O OE1 . GLN A 1 165 ? -2.387 26.467 0.409 1.00 45.90 ? 165 GLN A OE1 1 ATOM 1346 N NE2 . GLN A 1 165 ? -3.740 24.930 -0.538 1.00 44.50 ? 165 GLN A NE2 1 ATOM 1347 N N . HIS A 1 166 ? -0.116 20.809 -1.074 1.00 36.61 ? 166 HIS A N 1 ATOM 1348 C CA . HIS A 1 166 ? 0.527 20.084 -2.175 1.00 37.00 ? 166 HIS A CA 1 ATOM 1349 C C . HIS A 1 166 ? 1.869 19.440 -1.822 1.00 36.60 ? 166 HIS A C 1 ATOM 1350 O O . HIS A 1 166 ? 2.880 19.721 -2.471 1.00 36.88 ? 166 HIS A O 1 ATOM 1351 C CB . HIS A 1 166 ? 0.668 20.991 -3.396 1.00 37.35 ? 166 HIS A CB 1 ATOM 1352 C CG . HIS A 1 166 ? -0.626 21.602 -3.822 1.00 39.25 ? 166 HIS A CG 1 ATOM 1353 N ND1 . HIS A 1 166 ? -0.886 22.950 -3.704 1.00 40.65 ? 166 HIS A ND1 1 ATOM 1354 C CD2 . HIS A 1 166 ? -1.755 21.037 -4.313 1.00 40.30 ? 166 HIS A CD2 1 ATOM 1355 C CE1 . HIS A 1 166 ? -2.113 23.193 -4.130 1.00 42.40 ? 166 HIS A CE1 1 ATOM 1356 N NE2 . HIS A 1 166 ? -2.660 22.049 -4.506 1.00 41.96 ? 166 HIS A NE2 1 ATOM 1357 N N . PRO A 1 167 ? 1.880 18.558 -0.802 1.00 36.16 ? 167 PRO A N 1 ATOM 1358 C CA . PRO A 1 167 ? 3.111 17.849 -0.453 1.00 35.91 ? 167 PRO A CA 1 ATOM 1359 C C . PRO A 1 167 ? 3.594 16.929 -1.581 1.00 36.03 ? 167 PRO A C 1 ATOM 1360 O O . PRO A 1 167 ? 4.774 16.582 -1.630 1.00 35.94 ? 167 PRO A O 1 ATOM 1361 C CB . PRO A 1 167 ? 2.698 17.017 0.766 1.00 35.93 ? 167 PRO A CB 1 ATOM 1362 C CG . PRO A 1 167 ? 1.213 16.873 0.647 1.00 35.61 ? 167 PRO A CG 1 ATOM 1363 C CD . PRO A 1 167 ? 0.745 18.144 0.048 1.00 35.73 ? 167 PRO A CD 1 ATOM 1364 N N . GLU A 1 168 ? 2.683 16.542 -2.473 1.00 36.30 ? 168 GLU A N 1 ATOM 1365 C CA . GLU A 1 168 ? 3.005 15.685 -3.619 1.00 36.64 ? 168 GLU A CA 1 ATOM 1366 C C . GLU A 1 168 ? 3.913 16.401 -4.614 1.00 36.55 ? 168 GLU A C 1 ATOM 1367 O O . GLU A 1 168 ? 4.689 15.756 -5.319 1.00 36.66 ? 168 GLU A O 1 ATOM 1368 C CB . GLU A 1 168 ? 1.725 15.173 -4.312 1.00 37.05 ? 168 GLU A CB 1 ATOM 1369 C CG . GLU A 1 168 ? 0.929 16.211 -5.160 1.00 38.60 ? 168 GLU A CG 1 ATOM 1370 C CD . GLU A 1 168 ? 0.123 17.216 -4.331 1.00 41.52 ? 168 GLU A CD 1 ATOM 1371 O OE1 . GLU A 1 168 ? -0.411 18.180 -4.923 1.00 42.35 ? 168 GLU A OE1 1 ATOM 1372 O OE2 . GLU A 1 168 ? 0.020 17.057 -3.095 1.00 42.81 ? 168 GLU A OE2 1 ATOM 1373 N N . VAL A 1 169 ? 3.809 17.733 -4.654 1.00 36.28 ? 169 VAL A N 1 ATOM 1374 C CA . VAL A 1 169 ? 4.637 18.573 -5.517 1.00 36.00 ? 169 VAL A CA 1 ATOM 1375 C C . VAL A 1 169 ? 5.921 19.026 -4.816 1.00 35.71 ? 169 VAL A C 1 ATOM 1376 O O . VAL A 1 169 ? 6.990 19.039 -5.428 1.00 35.65 ? 169 VAL A O 1 ATOM 1377 C CB . VAL A 1 169 ? 3.858 19.813 -6.033 1.00 36.17 ? 169 VAL A CB 1 ATOM 1378 C CG1 . VAL A 1 169 ? 4.743 20.680 -6.925 1.00 36.06 ? 169 VAL A CG1 1 ATOM 1379 C CG2 . VAL A 1 169 ? 2.603 19.383 -6.784 1.00 36.33 ? 169 VAL A CG2 1 ATOM 1380 N N . ILE A 1 170 ? 5.811 19.399 -3.541 1.00 35.27 ? 170 ILE A N 1 ATOM 1381 C CA . ILE A 1 170 ? 6.971 19.864 -2.775 1.00 34.82 ? 170 ILE A CA 1 ATOM 1382 C C . ILE A 1 170 ? 7.988 18.729 -2.551 1.00 34.21 ? 170 ILE A C 1 ATOM 1383 O O . ILE A 1 170 ? 9.186 18.903 -2.787 1.00 33.96 ? 170 ILE A O 1 ATOM 1384 C CB . ILE A 1 170 ? 6.562 20.521 -1.414 1.00 35.08 ? 170 ILE A CB 1 ATOM 1385 C CG1 . ILE A 1 170 ? 5.448 21.575 -1.592 1.00 35.56 ? 170 ILE A CG1 1 ATOM 1386 C CG2 . ILE A 1 170 ? 7.788 21.088 -0.684 1.00 34.95 ? 170 ILE A CG2 1 ATOM 1387 C CD1 . ILE A 1 170 ? 5.742 22.699 -2.608 1.00 37.19 ? 170 ILE A CD1 1 ATOM 1388 N N . TYR A 1 171 ? 7.495 17.573 -2.112 1.00 33.38 ? 171 TYR A N 1 ATOM 1389 C CA . TYR A 1 171 ? 8.346 16.430 -1.795 1.00 32.48 ? 171 TYR A CA 1 ATOM 1390 C C . TYR A 1 171 ? 8.200 15.371 -2.878 1.00 32.51 ? 171 TYR A C 1 ATOM 1391 O O . TYR A 1 171 ? 7.405 14.439 -2.751 1.00 32.77 ? 171 TYR A O 1 ATOM 1392 C CB . TYR A 1 171 ? 7.993 15.857 -0.416 1.00 32.16 ? 171 TYR A CB 1 ATOM 1393 C CG . TYR A 1 171 ? 7.875 16.893 0.679 1.00 30.79 ? 171 TYR A CG 1 ATOM 1394 C CD1 . TYR A 1 171 ? 8.951 17.728 0.995 1.00 30.15 ? 171 TYR A CD1 1 ATOM 1395 C CD2 . TYR A 1 171 ? 6.691 17.041 1.403 1.00 29.16 ? 171 TYR A CD2 1 ATOM 1396 C CE1 . TYR A 1 171 ? 8.851 18.690 1.998 1.00 28.92 ? 171 TYR A CE1 1 ATOM 1397 C CE2 . TYR A 1 171 ? 6.584 18.000 2.412 1.00 28.88 ? 171 TYR A CE2 1 ATOM 1398 C CZ . TYR A 1 171 ? 7.671 18.819 2.699 1.00 28.52 ? 171 TYR A CZ 1 ATOM 1399 O OH . TYR A 1 171 ? 7.591 19.766 3.691 1.00 27.88 ? 171 TYR A OH 1 ATOM 1400 N N . THR A 1 172 ? 8.968 15.536 -3.950 1.00 32.30 ? 172 THR A N 1 ATOM 1401 C CA . THR A 1 172 ? 8.861 14.693 -5.142 1.00 31.88 ? 172 THR A CA 1 ATOM 1402 C C . THR A 1 172 ? 9.250 13.241 -4.902 1.00 30.97 ? 172 THR A C 1 ATOM 1403 O O . THR A 1 172 ? 8.697 12.345 -5.534 1.00 30.91 ? 172 THR A O 1 ATOM 1404 C CB . THR A 1 172 ? 9.700 15.254 -6.303 1.00 32.17 ? 172 THR A CB 1 ATOM 1405 O OG1 . THR A 1 172 ? 10.997 15.632 -5.816 1.00 33.36 ? 172 THR A OG1 1 ATOM 1406 C CG2 . THR A 1 172 ? 9.011 16.472 -6.899 1.00 32.60 ? 172 THR A CG2 1 ATOM 1407 N N . ASN A 1 173 ? 10.195 13.018 -3.994 1.00 29.79 ? 173 ASN A N 1 ATOM 1408 C CA . ASN A 1 173 ? 10.616 11.669 -3.629 1.00 28.71 ? 173 ASN A CA 1 ATOM 1409 C C . ASN A 1 173 ? 10.996 11.547 -2.148 1.00 28.08 ? 173 ASN A C 1 ATOM 1410 O O . ASN A 1 173 ? 10.955 12.521 -1.407 1.00 27.84 ? 173 ASN A O 1 ATOM 1411 C CB . ASN A 1 173 ? 11.780 11.220 -4.515 1.00 28.66 ? 173 ASN A CB 1 ATOM 1412 C CG . ASN A 1 173 ? 12.989 12.126 -4.385 1.00 28.86 ? 173 ASN A CG 1 ATOM 1413 O OD1 . ASN A 1 173 ? 13.582 12.257 -3.304 1.00 28.97 ? 173 ASN A OD1 1 ATOM 1414 N ND2 . ASN A 1 173 ? 13.359 12.770 -5.487 1.00 28.63 ? 173 ASN A ND2 1 ATOM 1415 N N . GLN A 1 174 ? 11.395 10.345 -1.743 1.00 27.34 ? 174 GLN A N 1 ATOM 1416 C CA . GLN A 1 174 ? 11.726 10.058 -0.358 1.00 26.78 ? 174 GLN A CA 1 ATOM 1417 C C . GLN A 1 174 ? 13.008 10.737 0.120 1.00 26.88 ? 174 GLN A C 1 ATOM 1418 O O . GLN A 1 174 ? 13.122 11.080 1.303 1.00 26.87 ? 174 GLN A O 1 ATOM 1419 C CB . GLN A 1 174 ? 11.757 8.544 -0.121 1.00 26.59 ? 174 GLN A CB 1 ATOM 1420 C CG . GLN A 1 174 ? 10.346 7.963 -0.014 1.00 26.06 ? 174 GLN A CG 1 ATOM 1421 C CD . GLN A 1 174 ? 10.271 6.445 0.059 1.00 25.68 ? 174 GLN A CD 1 ATOM 1422 O OE1 . GLN A 1 174 ? 9.253 5.869 -0.313 1.00 26.73 ? 174 GLN A OE1 1 ATOM 1423 N NE2 . GLN A 1 174 ? 11.323 5.796 0.552 1.00 24.36 ? 174 GLN A NE2 1 ATOM 1424 N N . ASN A 1 175 ? 13.956 10.954 -0.792 1.00 26.58 ? 175 ASN A N 1 ATOM 1425 C CA . ASN A 1 175 ? 15.183 11.673 -0.451 1.00 26.46 ? 175 ASN A CA 1 ATOM 1426 C C . ASN A 1 175 ? 14.931 13.162 -0.212 1.00 26.37 ? 175 ASN A C 1 ATOM 1427 O O . ASN A 1 175 ? 15.515 13.763 0.691 1.00 26.38 ? 175 ASN A O 1 ATOM 1428 C CB . ASN A 1 175 ? 16.266 11.472 -1.521 1.00 26.45 ? 175 ASN A CB 1 ATOM 1429 C CG . ASN A 1 175 ? 16.939 10.117 -1.428 1.00 26.30 ? 175 ASN A CG 1 ATOM 1430 O OD1 . ASN A 1 175 ? 16.669 9.338 -0.519 1.00 27.10 ? 175 ASN A OD1 1 ATOM 1431 N ND2 . ASN A 1 175 ? 17.822 9.830 -2.372 1.00 26.74 ? 175 ASN A ND2 1 ATOM 1432 N N . VAL A 1 176 ? 14.049 13.754 -1.009 1.00 26.15 ? 176 VAL A N 1 ATOM 1433 C CA . VAL A 1 176 ? 13.714 15.163 -0.830 1.00 25.91 ? 176 VAL A CA 1 ATOM 1434 C C . VAL A 1 176 ? 13.033 15.379 0.531 1.00 26.17 ? 176 VAL A C 1 ATOM 1435 O O . VAL A 1 176 ? 13.410 16.297 1.276 1.00 26.16 ? 176 VAL A O 1 ATOM 1436 C CB . VAL A 1 176 ? 12.869 15.713 -2.008 1.00 25.94 ? 176 VAL A CB 1 ATOM 1437 C CG1 . VAL A 1 176 ? 12.421 17.150 -1.753 1.00 25.10 ? 176 VAL A CG1 1 ATOM 1438 C CG2 . VAL A 1 176 ? 13.659 15.625 -3.302 1.00 25.18 ? 176 VAL A CG2 1 ATOM 1439 N N . VAL A 1 177 ? 12.062 14.523 0.864 1.00 25.87 ? 177 VAL A N 1 ATOM 1440 C CA . VAL A 1 177 ? 11.378 14.631 2.152 1.00 25.72 ? 177 VAL A CA 1 ATOM 1441 C C . VAL A 1 177 ? 12.330 14.406 3.340 1.00 26.15 ? 177 VAL A C 1 ATOM 1442 O O . VAL A 1 177 ? 12.250 15.115 4.342 1.00 25.96 ? 177 VAL A O 1 ATOM 1443 C CB . VAL A 1 177 ? 10.051 13.784 2.228 1.00 25.48 ? 177 VAL A CB 1 ATOM 1444 C CG1 . VAL A 1 177 ? 10.316 12.297 2.441 1.00 24.65 ? 177 VAL A CG1 1 ATOM 1445 C CG2 . VAL A 1 177 ? 9.129 14.324 3.307 1.00 24.44 ? 177 VAL A CG2 1 ATOM 1446 N N . TRP A 1 178 ? 13.249 13.456 3.214 1.00 26.95 ? 178 TRP A N 1 ATOM 1447 C CA . TRP A 1 178 ? 14.210 13.203 4.291 1.00 27.99 ? 178 TRP A CA 1 ATOM 1448 C C . TRP A 1 178 ? 15.209 14.338 4.439 1.00 28.57 ? 178 TRP A C 1 ATOM 1449 O O . TRP A 1 178 ? 15.637 14.654 5.544 1.00 28.60 ? 178 TRP A O 1 ATOM 1450 C CB . TRP A 1 178 ? 14.921 11.856 4.125 1.00 27.87 ? 178 TRP A CB 1 ATOM 1451 C CG . TRP A 1 178 ? 14.322 10.799 4.985 1.00 28.19 ? 178 TRP A CG 1 ATOM 1452 C CD1 . TRP A 1 178 ? 13.351 9.912 4.636 1.00 28.30 ? 178 TRP A CD1 1 ATOM 1453 C CD2 . TRP A 1 178 ? 14.635 10.533 6.359 1.00 28.83 ? 178 TRP A CD2 1 ATOM 1454 N NE1 . TRP A 1 178 ? 13.045 9.100 5.704 1.00 28.07 ? 178 TRP A NE1 1 ATOM 1455 C CE2 . TRP A 1 178 ? 13.817 9.460 6.773 1.00 28.38 ? 178 TRP A CE2 1 ATOM 1456 C CE3 . TRP A 1 178 ? 15.534 11.093 7.278 1.00 28.45 ? 178 TRP A CE3 1 ATOM 1457 C CZ2 . TRP A 1 178 ? 13.867 8.935 8.069 1.00 29.14 ? 178 TRP A CZ2 1 ATOM 1458 C CZ3 . TRP A 1 178 ? 15.581 10.572 8.570 1.00 28.41 ? 178 TRP A CZ3 1 ATOM 1459 C CH2 . TRP A 1 178 ? 14.751 9.503 8.952 1.00 28.91 ? 178 TRP A CH2 1 ATOM 1460 N N . SER A 1 179 ? 15.561 14.954 3.316 1.00 29.62 ? 179 SER A N 1 ATOM 1461 C CA . SER A 1 179 ? 16.418 16.132 3.303 1.00 30.59 ? 179 SER A CA 1 ATOM 1462 C C . SER A 1 179 ? 15.806 17.295 4.102 1.00 31.06 ? 179 SER A C 1 ATOM 1463 O O . SER A 1 179 ? 16.463 17.871 4.977 1.00 31.41 ? 179 SER A O 1 ATOM 1464 C CB . SER A 1 179 ? 16.675 16.557 1.867 1.00 30.52 ? 179 SER A CB 1 ATOM 1465 O OG . SER A 1 179 ? 17.582 17.628 1.838 1.00 32.12 ? 179 SER A OG 1 ATOM 1466 N N . LYS A 1 180 ? 14.551 17.626 3.804 1.00 31.36 ? 180 LYS A N 1 ATOM 1467 C CA . LYS A 1 180 ? 13.814 18.650 4.547 1.00 31.94 ? 180 LYS A CA 1 ATOM 1468 C C . LYS A 1 180 ? 13.608 18.269 6.018 1.00 31.84 ? 180 LYS A C 1 ATOM 1469 O O . LYS A 1 180 ? 13.797 19.104 6.902 1.00 31.70 ? 180 LYS A O 1 ATOM 1470 C CB . LYS A 1 180 ? 12.462 18.934 3.887 1.00 32.16 ? 180 LYS A CB 1 ATOM 1471 C CG . LYS A 1 180 ? 12.541 19.346 2.414 1.00 34.39 ? 180 LYS A CG 1 ATOM 1472 C CD . LYS A 1 180 ? 13.223 20.708 2.220 1.00 37.19 ? 180 LYS A CD 1 ATOM 1473 C CE . LYS A 1 180 ? 13.285 21.097 0.740 1.00 38.31 ? 180 LYS A CE 1 ATOM 1474 N NZ . LYS A 1 180 ? 14.149 22.285 0.503 1.00 38.31 ? 180 LYS A NZ 1 ATOM 1475 N N . PHE A 1 181 ? 13.219 17.012 6.260 1.00 31.76 ? 181 PHE A N 1 ATOM 1476 C CA . PHE A 1 181 ? 13.061 16.461 7.612 1.00 31.82 ? 181 PHE A CA 1 ATOM 1477 C C . PHE A 1 181 ? 14.277 16.765 8.474 1.00 31.83 ? 181 PHE A C 1 ATOM 1478 O O . PHE A 1 181 ? 14.161 17.435 9.498 1.00 31.63 ? 181 PHE A O 1 ATOM 1479 C CB . PHE A 1 181 ? 12.839 14.941 7.552 1.00 31.79 ? 181 PHE A CB 1 ATOM 1480 C CG . PHE A 1 181 ? 12.240 14.341 8.803 1.00 31.16 ? 181 PHE A CG 1 ATOM 1481 C CD1 . PHE A 1 181 ? 11.171 14.944 9.455 1.00 30.12 ? 181 PHE A CD1 1 ATOM 1482 C CD2 . PHE A 1 181 ? 12.716 13.126 9.295 1.00 31.21 ? 181 PHE A CD2 1 ATOM 1483 C CE1 . PHE A 1 181 ? 10.611 14.363 10.598 1.00 29.69 ? 181 PHE A CE1 1 ATOM 1484 C CE2 . PHE A 1 181 ? 12.155 12.531 10.434 1.00 29.89 ? 181 PHE A CE2 1 ATOM 1485 C CZ . PHE A 1 181 ? 11.104 13.154 11.083 1.00 29.65 ? 181 PHE A CZ 1 ATOM 1486 N N . GLU A 1 182 ? 15.442 16.294 8.034 1.00 32.06 ? 182 GLU A N 1 ATOM 1487 C CA . GLU A 1 182 ? 16.680 16.455 8.794 1.00 32.49 ? 182 GLU A CA 1 ATOM 1488 C C . GLU A 1 182 ? 17.084 17.919 8.957 1.00 31.86 ? 182 GLU A C 1 ATOM 1489 O O . GLU A 1 182 ? 17.607 18.302 10.009 1.00 31.86 ? 182 GLU A O 1 ATOM 1490 C CB . GLU A 1 182 ? 17.815 15.652 8.158 1.00 32.79 ? 182 GLU A CB 1 ATOM 1491 C CG . GLU A 1 182 ? 18.619 14.830 9.161 1.00 36.09 ? 182 GLU A CG 1 ATOM 1492 C CD . GLU A 1 182 ? 17.971 13.494 9.478 1.00 38.67 ? 182 GLU A CD 1 ATOM 1493 O OE1 . GLU A 1 182 ? 18.454 12.774 10.368 1.00 38.84 ? 182 GLU A OE1 1 ATOM 1494 O OE2 . GLU A 1 182 ? 16.974 13.159 8.822 1.00 41.77 ? 182 GLU A OE2 1 ATOM 1495 N N . THR A 1 183 ? 16.827 18.731 7.929 1.00 31.26 ? 183 THR A N 1 ATOM 1496 C CA . THR A 1 183 ? 17.078 20.176 7.984 1.00 30.74 ? 183 THR A CA 1 ATOM 1497 C C . THR A 1 183 ? 16.267 20.875 9.089 1.00 30.64 ? 183 THR A C 1 ATOM 1498 O O . THR A 1 183 ? 16.780 21.773 9.767 1.00 30.63 ? 183 THR A O 1 ATOM 1499 C CB . THR A 1 183 ? 16.853 20.845 6.606 1.00 30.81 ? 183 THR A CB 1 ATOM 1500 O OG1 . THR A 1 183 ? 17.791 20.308 5.669 1.00 30.38 ? 183 THR A OG1 1 ATOM 1501 C CG2 . THR A 1 183 ? 17.035 22.354 6.677 1.00 29.75 ? 183 THR A CG2 1 ATOM 1502 N N . ILE A 1 184 ? 15.019 20.453 9.283 1.00 30.42 ? 184 ILE A N 1 ATOM 1503 C CA . ILE A 1 184 ? 14.216 20.954 10.406 1.00 30.36 ? 184 ILE A CA 1 ATOM 1504 C C . ILE A 1 184 ? 14.879 20.670 11.760 1.00 30.80 ? 184 ILE A C 1 ATOM 1505 O O . ILE A 1 184 ? 15.023 21.581 12.584 1.00 30.53 ? 184 ILE A O 1 ATOM 1506 C CB . ILE A 1 184 ? 12.765 20.427 10.378 1.00 30.16 ? 184 ILE A CB 1 ATOM 1507 C CG1 . ILE A 1 184 ? 12.059 20.951 9.124 1.00 29.44 ? 184 ILE A CG1 1 ATOM 1508 C CG2 . ILE A 1 184 ? 12.008 20.839 11.662 1.00 28.99 ? 184 ILE A CG2 1 ATOM 1509 C CD1 . ILE A 1 184 ? 10.731 20.304 8.837 1.00 29.51 ? 184 ILE A CD1 1 ATOM 1510 N N . PHE A 1 185 ? 15.297 19.422 11.975 1.00 31.22 ? 185 PHE A N 1 ATOM 1511 C CA . PHE A 1 185 ? 16.017 19.057 13.200 1.00 32.16 ? 185 PHE A CA 1 ATOM 1512 C C . PHE A 1 185 ? 17.234 19.962 13.436 1.00 32.57 ? 185 PHE A C 1 ATOM 1513 O O . PHE A 1 185 ? 17.415 20.477 14.537 1.00 32.59 ? 185 PHE A O 1 ATOM 1514 C CB . PHE A 1 185 ? 16.427 17.567 13.214 1.00 32.06 ? 185 PHE A CB 1 ATOM 1515 C CG . PHE A 1 185 ? 15.266 16.611 13.360 1.00 32.11 ? 185 PHE A CG 1 ATOM 1516 C CD1 . PHE A 1 185 ? 14.676 16.386 14.606 1.00 32.94 ? 185 PHE A CD1 1 ATOM 1517 C CD2 . PHE A 1 185 ? 14.764 15.932 12.258 1.00 31.56 ? 185 PHE A CD2 1 ATOM 1518 C CE1 . PHE A 1 185 ? 13.595 15.502 14.749 1.00 32.39 ? 185 PHE A CE1 1 ATOM 1519 C CE2 . PHE A 1 185 ? 13.686 15.053 12.387 1.00 31.67 ? 185 PHE A CE2 1 ATOM 1520 C CZ . PHE A 1 185 ? 13.099 14.835 13.631 1.00 31.73 ? 185 PHE A CZ 1 ATOM 1521 N N . PHE A 1 186 ? 18.038 20.165 12.389 1.00 33.28 ? 186 PHE A N 1 ATOM 1522 C CA . PHE A 1 186 ? 19.200 21.058 12.432 1.00 33.80 ? 186 PHE A CA 1 ATOM 1523 C C . PHE A 1 186 ? 18.842 22.498 12.812 1.00 33.79 ? 186 PHE A C 1 ATOM 1524 O O . PHE A 1 186 ? 19.524 23.104 13.635 1.00 34.07 ? 186 PHE A O 1 ATOM 1525 C CB . PHE A 1 186 ? 19.947 21.050 11.090 1.00 34.17 ? 186 PHE A CB 1 ATOM 1526 C CG . PHE A 1 186 ? 21.007 22.114 10.981 1.00 35.47 ? 186 PHE A CG 1 ATOM 1527 C CD1 . PHE A 1 186 ? 20.685 23.391 10.522 1.00 36.99 ? 186 PHE A CD1 1 ATOM 1528 C CD2 . PHE A 1 186 ? 22.324 21.845 11.352 1.00 36.79 ? 186 PHE A CD2 1 ATOM 1529 C CE1 . PHE A 1 186 ? 21.657 24.389 10.430 1.00 38.56 ? 186 PHE A CE1 1 ATOM 1530 C CE2 . PHE A 1 186 ? 23.312 22.831 11.260 1.00 37.81 ? 186 PHE A CE2 1 ATOM 1531 C CZ . PHE A 1 186 ? 22.979 24.106 10.801 1.00 38.57 ? 186 PHE A CZ 1 ATOM 1532 N N . THR A 1 187 ? 17.791 23.039 12.195 1.00 33.84 ? 187 THR A N 1 ATOM 1533 C CA . THR A 1 187 ? 17.344 24.417 12.435 1.00 33.77 ? 187 THR A CA 1 ATOM 1534 C C . THR A 1 187 ? 16.893 24.654 13.882 1.00 33.69 ? 187 THR A C 1 ATOM 1535 O O . THR A 1 187 ? 17.394 25.560 14.543 1.00 34.05 ? 187 THR A O 1 ATOM 1536 C CB . THR A 1 187 ? 16.214 24.818 11.451 1.00 33.85 ? 187 THR A CB 1 ATOM 1537 O OG1 . THR A 1 187 ? 16.709 24.749 10.107 1.00 33.84 ? 187 THR A OG1 1 ATOM 1538 C CG2 . THR A 1 187 ? 15.706 26.230 11.731 1.00 33.61 ? 187 THR A CG2 1 ATOM 1539 N N . ILE A 1 188 ? 15.966 23.832 14.370 1.00 33.40 ? 188 ILE A N 1 ATOM 1540 C CA . ILE A 1 188 ? 15.362 24.027 15.696 1.00 33.04 ? 188 ILE A CA 1 ATOM 1541 C C . ILE A 1 188 ? 16.292 23.593 16.824 1.00 32.91 ? 188 ILE A C 1 ATOM 1542 O O . ILE A 1 188 ? 16.018 23.845 18.003 1.00 32.88 ? 188 ILE A O 1 ATOM 1543 C CB . ILE A 1 188 ? 14.008 23.271 15.840 1.00 33.11 ? 188 ILE A CB 1 ATOM 1544 C CG1 . ILE A 1 188 ? 14.232 21.750 15.756 1.00 32.96 ? 188 ILE A CG1 1 ATOM 1545 C CG2 . ILE A 1 188 ? 12.973 23.801 14.815 1.00 32.46 ? 188 ILE A CG2 1 ATOM 1546 C CD1 . ILE A 1 188 ? 13.077 20.903 16.215 1.00 33.15 ? 188 ILE A CD1 1 ATOM 1547 N N . SER A 1 189 ? 17.393 22.948 16.453 1.00 32.57 ? 189 SER A N 1 ATOM 1548 C CA . SER A 1 189 ? 18.332 22.407 17.427 1.00 32.50 ? 189 SER A CA 1 ATOM 1549 C C . SER A 1 189 ? 18.900 23.461 18.378 1.00 32.12 ? 189 SER A C 1 ATOM 1550 O O . SER A 1 189 ? 18.878 23.277 19.590 1.00 31.95 ? 189 SER A O 1 ATOM 1551 C CB . SER A 1 189 ? 19.465 21.670 16.720 1.00 32.63 ? 189 SER A CB 1 ATOM 1552 O OG . SER A 1 189 ? 20.062 20.749 17.606 1.00 33.33 ? 189 SER A OG 1 ATOM 1553 N N . GLY A 1 190 ? 19.395 24.563 17.816 1.00 31.92 ? 190 GLY A N 1 ATOM 1554 C CA . GLY A 1 190 ? 19.957 25.662 18.596 1.00 31.80 ? 190 GLY A CA 1 ATOM 1555 C C . GLY A 1 190 ? 18.986 26.287 19.578 1.00 31.76 ? 190 GLY A C 1 ATOM 1556 O O . GLY A 1 190 ? 19.394 26.769 20.627 1.00 31.73 ? 190 GLY A O 1 ATOM 1557 N N . LEU A 1 191 ? 17.700 26.278 19.236 1.00 31.75 ? 191 LEU A N 1 ATOM 1558 C CA . LEU A 1 191 ? 16.665 26.781 20.132 1.00 31.95 ? 191 LEU A CA 1 ATOM 1559 C C . LEU A 1 191 ? 16.471 25.871 21.342 1.00 32.15 ? 191 LEU A C 1 ATOM 1560 O O . LEU A 1 191 ? 16.445 26.345 22.478 1.00 32.52 ? 191 LEU A O 1 ATOM 1561 C CB . LEU A 1 191 ? 15.338 26.951 19.394 1.00 31.78 ? 191 LEU A CB 1 ATOM 1562 C CG . LEU A 1 191 ? 15.260 28.053 18.337 1.00 31.95 ? 191 LEU A CG 1 ATOM 1563 C CD1 . LEU A 1 191 ? 14.051 27.849 17.432 1.00 30.78 ? 191 LEU A CD1 1 ATOM 1564 C CD2 . LEU A 1 191 ? 15.224 29.432 18.999 1.00 31.81 ? 191 LEU A CD2 1 ATOM 1565 N N . ILE A 1 192 ? 16.359 24.565 21.094 1.00 32.01 ? 192 ILE A N 1 ATOM 1566 C CA . ILE A 1 192 ? 15.973 23.608 22.135 1.00 31.79 ? 192 ILE A CA 1 ATOM 1567 C C . ILE A 1 192 ? 17.113 23.228 23.097 1.00 31.57 ? 192 ILE A C 1 ATOM 1568 O O . ILE A 1 192 ? 16.864 22.868 24.246 1.00 31.39 ? 192 ILE A O 1 ATOM 1569 C CB . ILE A 1 192 ? 15.299 22.347 21.521 1.00 31.79 ? 192 ILE A CB 1 ATOM 1570 C CG1 . ILE A 1 192 ? 14.040 22.758 20.738 1.00 31.72 ? 192 ILE A CG1 1 ATOM 1571 C CG2 . ILE A 1 192 ? 14.959 21.309 22.605 1.00 31.15 ? 192 ILE A CG2 1 ATOM 1572 C CD1 . ILE A 1 192 ? 13.497 21.691 19.811 1.00 31.94 ? 192 ILE A CD1 1 ATOM 1573 N N . HIS A 1 193 ? 18.355 23.336 22.642 1.00 31.32 ? 193 HIS A N 1 ATOM 1574 C CA . HIS A 1 193 ? 19.488 22.880 23.446 1.00 31.31 ? 193 HIS A CA 1 ATOM 1575 C C . HIS A 1 193 ? 20.115 23.941 24.360 1.00 31.04 ? 193 HIS A C 1 ATOM 1576 O O . HIS A 1 193 ? 21.117 23.688 25.016 1.00 30.97 ? 193 HIS A O 1 ATOM 1577 C CB . HIS A 1 193 ? 20.522 22.194 22.563 1.00 31.19 ? 193 HIS A CB 1 ATOM 1578 C CG . HIS A 1 193 ? 20.057 20.883 22.017 1.00 32.58 ? 193 HIS A CG 1 ATOM 1579 N ND1 . HIS A 1 193 ? 20.115 19.713 22.744 1.00 34.48 ? 193 HIS A ND1 1 ATOM 1580 C CD2 . HIS A 1 193 ? 19.520 20.554 20.820 1.00 33.25 ? 193 HIS A CD2 1 ATOM 1581 C CE1 . HIS A 1 193 ? 19.638 18.720 22.017 1.00 33.98 ? 193 HIS A CE1 1 ATOM 1582 N NE2 . HIS A 1 193 ? 19.271 19.203 20.845 1.00 33.87 ? 193 HIS A NE2 1 ATOM 1583 N N . TYR A 1 194 ? 19.516 25.125 24.394 1.00 30.96 ? 194 TYR A N 1 ATOM 1584 C CA . TYR A 1 194 ? 19.848 26.138 25.385 1.00 30.87 ? 194 TYR A CA 1 ATOM 1585 C C . TYR A 1 194 ? 19.184 25.732 26.702 1.00 30.85 ? 194 TYR A C 1 ATOM 1586 O O . TYR A 1 194 ? 17.978 25.491 26.741 1.00 31.22 ? 194 TYR A O 1 ATOM 1587 C CB . TYR A 1 194 ? 19.377 27.512 24.901 1.00 30.87 ? 194 TYR A CB 1 ATOM 1588 C CG . TYR A 1 194 ? 19.437 28.619 25.925 1.00 30.76 ? 194 TYR A CG 1 ATOM 1589 C CD1 . TYR A 1 194 ? 20.597 28.865 26.662 1.00 31.80 ? 194 TYR A CD1 1 ATOM 1590 C CD2 . TYR A 1 194 ? 18.337 29.433 26.147 1.00 30.42 ? 194 TYR A CD2 1 ATOM 1591 C CE1 . TYR A 1 194 ? 20.648 29.894 27.609 1.00 31.26 ? 194 TYR A CE1 1 ATOM 1592 C CE2 . TYR A 1 194 ? 18.382 30.462 27.064 1.00 30.82 ? 194 TYR A CE2 1 ATOM 1593 C CZ . TYR A 1 194 ? 19.537 30.685 27.794 1.00 31.11 ? 194 TYR A CZ 1 ATOM 1594 O OH . TYR A 1 194 ? 19.565 31.703 28.713 1.00 32.12 ? 194 TYR A OH 1 ATOM 1595 N N . ALA A 1 195 ? 19.977 25.658 27.769 1.00 30.61 ? 195 ALA A N 1 ATOM 1596 C CA . ALA A 1 195 ? 19.572 24.989 29.016 1.00 30.39 ? 195 ALA A CA 1 ATOM 1597 C C . ALA A 1 195 ? 18.174 25.292 29.571 1.00 30.41 ? 195 ALA A C 1 ATOM 1598 O O . ALA A 1 195 ? 17.431 24.356 29.840 1.00 30.53 ? 195 ALA A O 1 ATOM 1599 C CB . ALA A 1 195 ? 20.640 25.142 30.099 1.00 30.28 ? 195 ALA A CB 1 ATOM 1600 N N . PRO A 1 196 ? 17.811 26.585 29.756 1.00 30.41 ? 196 PRO A N 1 ATOM 1601 C CA . PRO A 1 196 ? 16.458 26.798 30.299 1.00 30.23 ? 196 PRO A CA 1 ATOM 1602 C C . PRO A 1 196 ? 15.306 26.525 29.315 1.00 30.22 ? 196 PRO A C 1 ATOM 1603 O O . PRO A 1 196 ? 14.178 26.271 29.747 1.00 30.37 ? 196 PRO A O 1 ATOM 1604 C CB . PRO A 1 196 ? 16.469 28.259 30.772 1.00 29.94 ? 196 PRO A CB 1 ATOM 1605 C CG . PRO A 1 196 ? 17.625 28.900 30.100 1.00 30.25 ? 196 PRO A CG 1 ATOM 1606 C CD . PRO A 1 196 ? 18.621 27.822 29.772 1.00 30.40 ? 196 PRO A CD 1 ATOM 1607 N N . VAL A 1 197 ? 15.579 26.558 28.016 1.00 30.25 ? 197 VAL A N 1 ATOM 1608 C CA . VAL A 1 197 ? 14.579 26.124 27.034 1.00 30.33 ? 197 VAL A CA 1 ATOM 1609 C C . VAL A 1 197 ? 14.446 24.589 27.073 1.00 30.36 ? 197 VAL A C 1 ATOM 1610 O O . VAL A 1 197 ? 13.328 24.048 27.066 1.00 30.19 ? 197 VAL A O 1 ATOM 1611 C CB . VAL A 1 197 ? 14.892 26.626 25.607 1.00 30.19 ? 197 VAL A CB 1 ATOM 1612 C CG1 . VAL A 1 197 ? 13.862 26.103 24.612 1.00 30.28 ? 197 VAL A CG1 1 ATOM 1613 C CG2 . VAL A 1 197 ? 14.920 28.141 25.584 1.00 29.63 ? 197 VAL A CG2 1 ATOM 1614 N N . PHE A 1 198 ? 15.588 23.908 27.148 1.00 30.17 ? 198 PHE A N 1 ATOM 1615 C CA . PHE A 1 198 ? 15.634 22.446 27.256 1.00 30.39 ? 198 PHE A CA 1 ATOM 1616 C C . PHE A 1 198 ? 14.728 21.910 28.379 1.00 30.36 ? 198 PHE A C 1 ATOM 1617 O O . PHE A 1 198 ? 13.903 21.024 28.144 1.00 30.31 ? 198 PHE A O 1 ATOM 1618 C CB . PHE A 1 198 ? 17.086 21.964 27.430 1.00 30.49 ? 198 PHE A CB 1 ATOM 1619 C CG . PHE A 1 198 ? 17.243 20.467 27.400 1.00 30.69 ? 198 PHE A CG 1 ATOM 1620 C CD1 . PHE A 1 198 ? 17.076 19.756 26.214 1.00 30.54 ? 198 PHE A CD1 1 ATOM 1621 C CD2 . PHE A 1 198 ? 17.565 19.765 28.560 1.00 31.24 ? 198 PHE A CD2 1 ATOM 1622 C CE1 . PHE A 1 198 ? 17.216 18.366 26.184 1.00 30.65 ? 198 PHE A CE1 1 ATOM 1623 C CE2 . PHE A 1 198 ? 17.709 18.371 28.544 1.00 31.41 ? 198 PHE A CE2 1 ATOM 1624 C CZ . PHE A 1 198 ? 17.537 17.671 27.349 1.00 31.07 ? 198 PHE A CZ 1 ATOM 1625 N N . ARG A 1 199 ? 14.873 22.462 29.582 1.00 30.29 ? 199 ARG A N 1 ATOM 1626 C CA . ARG A 1 199 ? 14.009 22.111 30.707 1.00 30.50 ? 199 ARG A CA 1 ATOM 1627 C C . ARG A 1 199 ? 12.539 22.373 30.387 1.00 30.66 ? 199 ARG A C 1 ATOM 1628 O O . ARG A 1 199 ? 11.696 21.493 30.577 1.00 30.85 ? 199 ARG A O 1 ATOM 1629 C CB . ARG A 1 199 ? 14.414 22.868 31.977 1.00 30.59 ? 199 ARG A CB 1 ATOM 1630 C CG . ARG A 1 199 ? 15.733 22.430 32.587 1.00 30.53 ? 199 ARG A CG 1 ATOM 1631 C CD . ARG A 1 199 ? 16.155 23.355 33.718 1.00 31.73 ? 199 ARG A CD 1 ATOM 1632 N NE . ARG A 1 199 ? 17.611 23.424 33.786 1.00 32.77 ? 199 ARG A NE 1 ATOM 1633 C CZ . ARG A 1 199 ? 18.340 24.499 33.495 1.00 33.11 ? 199 ARG A CZ 1 ATOM 1634 N NH1 . ARG A 1 199 ? 17.765 25.638 33.140 1.00 31.75 ? 199 ARG A NH1 1 ATOM 1635 N NH2 . ARG A 1 199 ? 19.663 24.433 33.577 1.00 34.90 ? 199 ARG A NH2 1 ATOM 1636 N N . ASP A 1 200 ? 12.244 23.576 29.894 1.00 30.62 ? 200 ASP A N 1 ATOM 1637 C CA . ASP A 1 200 ? 10.882 23.956 29.531 1.00 30.65 ? 200 ASP A CA 1 ATOM 1638 C C . ASP A 1 200 ? 10.298 23.052 28.445 1.00 30.18 ? 200 ASP A C 1 ATOM 1639 O O . ASP A 1 200 ? 9.124 22.663 28.522 1.00 30.23 ? 200 ASP A O 1 ATOM 1640 C CB . ASP A 1 200 ? 10.830 25.427 29.098 1.00 31.09 ? 200 ASP A CB 1 ATOM 1641 C CG . ASP A 1 200 ? 10.880 26.391 30.282 1.00 32.51 ? 200 ASP A CG 1 ATOM 1642 O OD1 . ASP A 1 200 ? 10.517 25.981 31.411 1.00 34.07 ? 200 ASP A OD1 1 ATOM 1643 O OD2 . ASP A 1 200 ? 11.268 27.563 30.082 1.00 34.17 ? 200 ASP A OD2 1 ATOM 1644 N N . TYR A 1 201 ? 11.127 22.719 27.453 1.00 29.29 ? 201 TYR A N 1 ATOM 1645 C CA . TYR A 1 201 ? 10.753 21.811 26.372 1.00 28.44 ? 201 TYR A CA 1 ATOM 1646 C C . TYR A 1 201 ? 10.319 20.432 26.876 1.00 28.18 ? 201 TYR A C 1 ATOM 1647 O O . TYR A 1 201 ? 9.239 19.956 26.530 1.00 28.15 ? 201 TYR A O 1 ATOM 1648 C CB . TYR A 1 201 ? 11.905 21.654 25.372 1.00 28.23 ? 201 TYR A CB 1 ATOM 1649 C CG . TYR A 1 201 ? 11.500 20.880 24.136 1.00 27.78 ? 201 TYR A CG 1 ATOM 1650 C CD1 . TYR A 1 201 ? 11.545 19.481 24.111 1.00 26.03 ? 201 TYR A CD1 1 ATOM 1651 C CD2 . TYR A 1 201 ? 11.042 21.550 22.994 1.00 27.37 ? 201 TYR A CD2 1 ATOM 1652 C CE1 . TYR A 1 201 ? 11.153 18.772 22.980 1.00 26.68 ? 201 TYR A CE1 1 ATOM 1653 C CE2 . TYR A 1 201 ? 10.655 20.850 21.856 1.00 26.83 ? 201 TYR A CE2 1 ATOM 1654 C CZ . TYR A 1 201 ? 10.712 19.464 21.857 1.00 27.25 ? 201 TYR A CZ 1 ATOM 1655 O OH . TYR A 1 201 ? 10.327 18.777 20.735 1.00 28.04 ? 201 TYR A OH 1 ATOM 1656 N N . VAL A 1 202 ? 11.175 19.799 27.680 1.00 27.88 ? 202 VAL A N 1 ATOM 1657 C CA . VAL A 1 202 ? 10.895 18.483 28.261 1.00 27.50 ? 202 VAL A CA 1 ATOM 1658 C C . VAL A 1 202 ? 9.575 18.511 29.030 1.00 27.60 ? 202 VAL A C 1 ATOM 1659 O O . VAL A 1 202 ? 8.707 17.667 28.796 1.00 27.44 ? 202 VAL A O 1 ATOM 1660 C CB . VAL A 1 202 ? 12.048 18.009 29.193 1.00 27.58 ? 202 VAL A CB 1 ATOM 1661 C CG1 . VAL A 1 202 ? 11.678 16.710 29.931 1.00 26.98 ? 202 VAL A CG1 1 ATOM 1662 C CG2 . VAL A 1 202 ? 13.334 17.824 28.401 1.00 27.24 ? 202 VAL A CG2 1 ATOM 1663 N N . PHE A 1 203 ? 9.437 19.499 29.923 1.00 27.40 ? 203 PHE A N 1 ATOM 1664 C CA . PHE A 1 203 ? 8.238 19.707 30.724 1.00 27.42 ? 203 PHE A CA 1 ATOM 1665 C C . PHE A 1 203 ? 6.991 19.890 29.861 1.00 27.61 ? 203 PHE A C 1 ATOM 1666 O O . PHE A 1 203 ? 5.929 19.326 30.160 1.00 27.33 ? 203 PHE A O 1 ATOM 1667 C CB . PHE A 1 203 ? 8.422 20.913 31.655 1.00 27.65 ? 203 PHE A CB 1 ATOM 1668 C CG . PHE A 1 203 ? 7.431 20.968 32.777 1.00 27.63 ? 203 PHE A CG 1 ATOM 1669 C CD1 . PHE A 1 203 ? 6.240 21.677 32.638 1.00 28.15 ? 203 PHE A CD1 1 ATOM 1670 C CD2 . PHE A 1 203 ? 7.689 20.306 33.985 1.00 28.58 ? 203 PHE A CD2 1 ATOM 1671 C CE1 . PHE A 1 203 ? 5.305 21.729 33.698 1.00 29.41 ? 203 PHE A CE1 1 ATOM 1672 C CE2 . PHE A 1 203 ? 6.768 20.339 35.046 1.00 28.56 ? 203 PHE A CE2 1 ATOM 1673 C CZ . PHE A 1 203 ? 5.572 21.053 34.902 1.00 29.03 ? 203 PHE A CZ 1 ATOM 1674 N N . ARG A 1 204 ? 7.123 20.662 28.782 1.00 27.83 ? 204 ARG A N 1 ATOM 1675 C CA . ARG A 1 204 ? 5.976 20.922 27.920 1.00 28.29 ? 204 ARG A CA 1 ATOM 1676 C C . ARG A 1 204 ? 5.519 19.680 27.151 1.00 28.20 ? 204 ARG A C 1 ATOM 1677 O O . ARG A 1 204 ? 4.316 19.468 26.975 1.00 28.02 ? 204 ARG A O 1 ATOM 1678 C CB . ARG A 1 204 ? 6.222 22.083 26.970 1.00 28.30 ? 204 ARG A CB 1 ATOM 1679 C CG . ARG A 1 204 ? 4.921 22.640 26.462 1.00 30.32 ? 204 ARG A CG 1 ATOM 1680 C CD . ARG A 1 204 ? 5.122 23.808 25.567 1.00 34.95 ? 204 ARG A CD 1 ATOM 1681 N NE . ARG A 1 204 ? 3.887 24.104 24.852 1.00 40.72 ? 204 ARG A NE 1 ATOM 1682 C CZ . ARG A 1 204 ? 2.973 24.990 25.242 1.00 43.43 ? 204 ARG A CZ 1 ATOM 1683 N NH1 . ARG A 1 204 ? 3.142 25.701 26.353 1.00 44.21 ? 204 ARG A NH1 1 ATOM 1684 N NH2 . ARG A 1 204 ? 1.886 25.167 24.508 1.00 44.98 ? 204 ARG A NH2 1 ATOM 1685 N N . SER A 1 205 ? 6.470 18.859 26.712 1.00 28.11 ? 205 SER A N 1 ATOM 1686 C CA . SER A 1 205 ? 6.118 17.604 26.034 1.00 28.49 ? 205 SER A CA 1 ATOM 1687 C C . SER A 1 205 ? 5.337 16.653 26.948 1.00 28.76 ? 205 SER A C 1 ATOM 1688 O O . SER A 1 205 ? 4.468 15.920 26.481 1.00 28.66 ? 205 SER A O 1 ATOM 1689 C CB . SER A 1 205 ? 7.347 16.900 25.437 1.00 28.26 ? 205 SER A CB 1 ATOM 1690 O OG . SER A 1 205 ? 8.110 16.233 26.427 1.00 27.89 ? 205 SER A OG 1 ATOM 1691 N N . MET A 1 206 ? 5.649 16.665 28.243 1.00 29.39 ? 206 MET A N 1 ATOM 1692 C CA . MET A 1 206 ? 4.819 15.948 29.211 1.00 30.12 ? 206 MET A CA 1 ATOM 1693 C C . MET A 1 206 ? 3.427 16.567 29.330 1.00 30.81 ? 206 MET A C 1 ATOM 1694 O O . MET A 1 206 ? 2.441 15.840 29.311 1.00 31.05 ? 206 MET A O 1 ATOM 1695 C CB . MET A 1 206 ? 5.512 15.813 30.565 1.00 29.99 ? 206 MET A CB 1 ATOM 1696 C CG . MET A 1 206 ? 6.656 14.842 30.506 1.00 29.23 ? 206 MET A CG 1 ATOM 1697 S SD . MET A 1 206 ? 7.692 14.756 31.952 1.00 30.30 ? 206 MET A SD 1 ATOM 1698 C CE . MET A 1 206 ? 8.412 16.398 31.989 1.00 27.54 ? 206 MET A CE 1 ATOM 1699 N N . GLN A 1 207 ? 3.351 17.897 29.411 1.00 31.64 ? 207 GLN A N 1 ATOM 1700 C CA . GLN A 1 207 ? 2.061 18.601 29.415 1.00 32.70 ? 207 GLN A CA 1 ATOM 1701 C C . GLN A 1 207 ? 1.193 18.188 28.231 1.00 32.98 ? 207 GLN A C 1 ATOM 1702 O O . GLN A 1 207 ? 0.015 17.852 28.409 1.00 33.14 ? 207 GLN A O 1 ATOM 1703 C CB . GLN A 1 207 ? 2.247 20.127 29.412 1.00 32.95 ? 207 GLN A CB 1 ATOM 1704 C CG . GLN A 1 207 ? 2.588 20.714 30.773 1.00 34.41 ? 207 GLN A CG 1 ATOM 1705 C CD . GLN A 1 207 ? 2.925 22.195 30.712 1.00 36.31 ? 207 GLN A CD 1 ATOM 1706 O OE1 . GLN A 1 207 ? 3.752 22.635 29.905 1.00 37.50 ? 207 GLN A OE1 1 ATOM 1707 N NE2 . GLN A 1 207 ? 2.295 22.970 31.580 1.00 37.04 ? 207 GLN A NE2 1 ATOM 1708 N N . GLU A 1 208 ? 1.781 18.195 27.033 1.00 33.12 ? 208 GLU A N 1 ATOM 1709 C CA . GLU A 1 208 ? 1.026 17.920 25.803 1.00 33.45 ? 208 GLU A CA 1 ATOM 1710 C C . GLU A 1 208 ? 0.550 16.477 25.691 1.00 32.82 ? 208 GLU A C 1 ATOM 1711 O O . GLU A 1 208 ? -0.559 16.223 25.221 1.00 32.83 ? 208 GLU A O 1 ATOM 1712 C CB . GLU A 1 208 ? 1.792 18.357 24.551 1.00 33.81 ? 208 GLU A CB 1 ATOM 1713 C CG . GLU A 1 208 ? 1.853 19.886 24.395 1.00 36.33 ? 208 GLU A CG 1 ATOM 1714 C CD . GLU A 1 208 ? 2.434 20.354 23.067 1.00 39.42 ? 208 GLU A CD 1 ATOM 1715 O OE1 . GLU A 1 208 ? 2.514 19.553 22.109 1.00 40.28 ? 208 GLU A OE1 1 ATOM 1716 O OE2 . GLU A 1 208 ? 2.807 21.547 22.982 1.00 42.09 ? 208 GLU A OE2 1 ATOM 1717 N N . PHE A 1 209 ? 1.370 15.540 26.151 1.00 32.14 ? 209 PHE A N 1 ATOM 1718 C CA . PHE A 1 209 ? 0.958 14.145 26.172 1.00 31.61 ? 209 PHE A CA 1 ATOM 1719 C C . PHE A 1 209 ? 0.003 13.832 27.328 1.00 31.80 ? 209 PHE A C 1 ATOM 1720 O O . PHE A 1 209 ? -0.917 13.024 27.167 1.00 31.52 ? 209 PHE A O 1 ATOM 1721 C CB . PHE A 1 209 ? 2.166 13.212 26.149 1.00 31.33 ? 209 PHE A CB 1 ATOM 1722 C CG . PHE A 1 209 ? 2.718 12.983 24.772 1.00 30.10 ? 209 PHE A CG 1 ATOM 1723 C CD1 . PHE A 1 209 ? 2.513 11.771 24.124 1.00 28.82 ? 209 PHE A CD1 1 ATOM 1724 C CD2 . PHE A 1 209 ? 3.422 13.989 24.109 1.00 29.04 ? 209 PHE A CD2 1 ATOM 1725 C CE1 . PHE A 1 209 ? 3.018 11.544 22.841 1.00 27.94 ? 209 PHE A CE1 1 ATOM 1726 C CE2 . PHE A 1 209 ? 3.926 13.776 22.827 1.00 29.06 ? 209 PHE A CE2 1 ATOM 1727 C CZ . PHE A 1 209 ? 3.724 12.548 22.190 1.00 28.58 ? 209 PHE A CZ 1 ATOM 1728 N N . TYR A 1 210 ? 0.203 14.486 28.474 1.00 31.88 ? 210 TYR A N 1 ATOM 1729 C CA . TYR A 1 210 ? -0.725 14.357 29.595 1.00 32.21 ? 210 TYR A CA 1 ATOM 1730 C C . TYR A 1 210 ? -2.100 14.898 29.232 1.00 32.28 ? 210 TYR A C 1 ATOM 1731 O O . TYR A 1 210 ? -3.113 14.307 29.576 1.00 31.82 ? 210 TYR A O 1 ATOM 1732 C CB . TYR A 1 210 ? -0.215 15.087 30.830 1.00 32.47 ? 210 TYR A CB 1 ATOM 1733 C CG . TYR A 1 210 ? -1.119 14.921 32.030 1.00 32.92 ? 210 TYR A CG 1 ATOM 1734 C CD1 . TYR A 1 210 ? -1.064 13.761 32.813 1.00 33.69 ? 210 TYR A CD1 1 ATOM 1735 C CD2 . TYR A 1 210 ? -2.033 15.919 32.384 1.00 33.75 ? 210 TYR A CD2 1 ATOM 1736 C CE1 . TYR A 1 210 ? -1.900 13.598 33.920 1.00 34.35 ? 210 TYR A CE1 1 ATOM 1737 C CE2 . TYR A 1 210 ? -2.875 15.769 33.492 1.00 34.41 ? 210 TYR A CE2 1 ATOM 1738 C CZ . TYR A 1 210 ? -2.795 14.606 34.256 1.00 34.88 ? 210 TYR A CZ 1 ATOM 1739 O OH . TYR A 1 210 ? -3.616 14.452 35.354 1.00 36.67 ? 210 TYR A OH 1 ATOM 1740 N N . GLU A 1 211 ? -2.115 16.034 28.545 1.00 32.73 ? 211 GLU A N 1 ATOM 1741 C CA . GLU A 1 211 ? -3.341 16.632 28.051 1.00 33.41 ? 211 GLU A CA 1 ATOM 1742 C C . GLU A 1 211 ? -4.052 15.697 27.053 1.00 32.80 ? 211 GLU A C 1 ATOM 1743 O O . GLU A 1 211 ? -5.277 15.709 26.971 1.00 32.91 ? 211 GLU A O 1 ATOM 1744 C CB . GLU A 1 211 ? -3.027 18.008 27.444 1.00 34.14 ? 211 GLU A CB 1 ATOM 1745 C CG . GLU A 1 211 ? -4.226 18.890 27.135 1.00 38.29 ? 211 GLU A CG 1 ATOM 1746 C CD . GLU A 1 211 ? -4.827 18.622 25.762 1.00 44.38 ? 211 GLU A CD 1 ATOM 1747 O OE1 . GLU A 1 211 ? -4.142 18.006 24.903 1.00 47.81 ? 211 GLU A OE1 1 ATOM 1748 O OE2 . GLU A 1 211 ? -5.992 19.030 25.542 1.00 46.73 ? 211 GLU A OE2 1 ATOM 1749 N N . ASP A 1 212 ? -3.286 14.881 26.319 1.00 32.11 ? 212 ASP A N 1 ATOM 1750 C CA . ASP A 1 212 ? -3.851 13.920 25.361 1.00 31.31 ? 212 ASP A CA 1 ATOM 1751 C C . ASP A 1 212 ? -4.227 12.603 26.050 1.00 30.93 ? 212 ASP A C 1 ATOM 1752 O O . ASP A 1 212 ? -4.600 11.634 25.393 1.00 30.88 ? 212 ASP A O 1 ATOM 1753 C CB . ASP A 1 212 ? -2.882 13.674 24.188 1.00 31.48 ? 212 ASP A CB 1 ATOM 1754 C CG . ASP A 1 212 ? -3.574 13.085 22.940 1.00 31.90 ? 212 ASP A CG 1 ATOM 1755 O OD1 . ASP A 1 212 ? -4.632 13.603 22.517 1.00 32.79 ? 212 ASP A OD1 1 ATOM 1756 O OD2 . ASP A 1 212 ? -3.042 12.108 22.368 1.00 30.77 ? 212 ASP A OD2 1 ATOM 1757 N N . ASN A 1 213 ? -4.140 12.582 27.379 1.00 30.37 ? 213 ASN A N 1 ATOM 1758 C CA . ASN A 1 213 ? -4.492 11.406 28.191 1.00 29.91 ? 213 ASN A CA 1 ATOM 1759 C C . ASN A 1 213 ? -3.517 10.228 27.992 1.00 29.30 ? 213 ASN A C 1 ATOM 1760 O O . ASN A 1 213 ? -3.908 9.058 27.978 1.00 29.13 ? 213 ASN A O 1 ATOM 1761 C CB . ASN A 1 213 ? -5.968 11.003 27.975 1.00 30.04 ? 213 ASN A CB 1 ATOM 1762 C CG . ASN A 1 213 ? -6.564 10.249 29.168 1.00 31.22 ? 213 ASN A CG 1 ATOM 1763 O OD1 . ASN A 1 213 ? -5.855 9.860 30.096 1.00 33.04 ? 213 ASN A OD1 1 ATOM 1764 N ND2 . ASN A 1 213 ? -7.875 10.023 29.132 1.00 31.49 ? 213 ASN A ND2 1 ATOM 1765 N N . VAL A 1 214 ? -2.242 10.569 27.838 1.00 28.52 ? 214 VAL A N 1 ATOM 1766 C CA . VAL A 1 214 ? -1.141 9.607 27.786 1.00 27.97 ? 214 VAL A CA 1 ATOM 1767 C C . VAL A 1 214 ? -0.310 9.796 29.065 1.00 27.97 ? 214 VAL A C 1 ATOM 1768 O O . VAL A 1 214 ? 0.009 10.927 29.447 1.00 27.95 ? 214 VAL A O 1 ATOM 1769 C CB . VAL A 1 214 ? -0.264 9.831 26.507 1.00 27.81 ? 214 VAL A CB 1 ATOM 1770 C CG1 . VAL A 1 214 ? 0.927 8.881 26.463 1.00 26.68 ? 214 VAL A CG1 1 ATOM 1771 C CG2 . VAL A 1 214 ? -1.110 9.715 25.241 1.00 27.06 ? 214 VAL A CG2 1 ATOM 1772 N N . LEU A 1 215 ? 0.039 8.702 29.727 1.00 27.91 ? 215 LEU A N 1 ATOM 1773 C CA . LEU A 1 215 ? 0.590 8.804 31.076 1.00 28.37 ? 215 LEU A CA 1 ATOM 1774 C C . LEU A 1 215 ? 2.055 8.417 31.221 1.00 28.67 ? 215 LEU A C 1 ATOM 1775 O O . LEU A 1 215 ? 2.645 8.600 32.292 1.00 28.90 ? 215 LEU A O 1 ATOM 1776 C CB . LEU A 1 215 ? -0.270 8.010 32.065 1.00 28.50 ? 215 LEU A CB 1 ATOM 1777 C CG . LEU A 1 215 ? -1.707 8.524 32.212 1.00 27.96 ? 215 LEU A CG 1 ATOM 1778 C CD1 . LEU A 1 215 ? -2.538 7.552 33.029 1.00 28.25 ? 215 LEU A CD1 1 ATOM 1779 C CD2 . LEU A 1 215 ? -1.728 9.915 32.815 1.00 27.38 ? 215 LEU A CD2 1 ATOM 1780 N N . TYR A 1 216 ? 2.644 7.897 30.150 1.00 28.76 ? 216 TYR A N 1 ATOM 1781 C CA . TYR A 1 216 ? 4.041 7.476 30.189 1.00 28.63 ? 216 TYR A CA 1 ATOM 1782 C C . TYR A 1 216 ? 4.689 7.677 28.827 1.00 28.52 ? 216 TYR A C 1 ATOM 1783 O O . TYR A 1 216 ? 4.018 7.582 27.792 1.00 28.61 ? 216 TYR A O 1 ATOM 1784 C CB . TYR A 1 216 ? 4.123 6.018 30.640 1.00 28.43 ? 216 TYR A CB 1 ATOM 1785 C CG . TYR A 1 216 ? 5.498 5.417 30.682 1.00 28.34 ? 216 TYR A CG 1 ATOM 1786 C CD1 . TYR A 1 216 ? 6.461 5.883 31.573 1.00 28.69 ? 216 TYR A CD1 1 ATOM 1787 C CD2 . TYR A 1 216 ? 5.830 4.348 29.853 1.00 28.33 ? 216 TYR A CD2 1 ATOM 1788 C CE1 . TYR A 1 216 ? 7.729 5.312 31.620 1.00 28.21 ? 216 TYR A CE1 1 ATOM 1789 C CE2 . TYR A 1 216 ? 7.088 3.765 29.898 1.00 27.77 ? 216 TYR A CE2 1 ATOM 1790 C CZ . TYR A 1 216 ? 8.026 4.254 30.781 1.00 28.19 ? 216 TYR A CZ 1 ATOM 1791 O OH . TYR A 1 216 ? 9.272 3.687 30.824 1.00 28.68 ? 216 TYR A OH 1 ATOM 1792 N N . MET A 1 217 ? 5.988 7.973 28.837 1.00 28.29 ? 217 MET A N 1 ATOM 1793 C CA . MET A 1 217 ? 6.736 8.220 27.603 1.00 28.07 ? 217 MET A CA 1 ATOM 1794 C C . MET A 1 217 ? 8.122 7.579 27.625 1.00 27.89 ? 217 MET A C 1 ATOM 1795 O O . MET A 1 217 ? 8.867 7.706 28.595 1.00 27.88 ? 217 MET A O 1 ATOM 1796 C CB . MET A 1 217 ? 6.877 9.732 27.356 1.00 28.13 ? 217 MET A CB 1 ATOM 1797 C CG . MET A 1 217 ? 5.569 10.510 27.248 1.00 27.59 ? 217 MET A CG 1 ATOM 1798 S SD . MET A 1 217 ? 5.847 12.284 27.094 1.00 27.69 ? 217 MET A SD 1 ATOM 1799 C CE . MET A 1 217 ? 6.092 12.722 28.758 1.00 30.70 ? 217 MET A CE 1 ATOM 1800 N N . GLU A 1 218 ? 8.465 6.884 26.552 1.00 27.90 ? 218 GLU A N 1 ATOM 1801 C CA . GLU A 1 218 ? 9.856 6.486 26.330 1.00 28.12 ? 218 GLU A CA 1 ATOM 1802 C C . GLU A 1 218 ? 10.388 7.201 25.080 1.00 27.96 ? 218 GLU A C 1 ATOM 1803 O O . GLU A 1 218 ? 9.767 7.153 24.019 1.00 27.86 ? 218 GLU A O 1 ATOM 1804 C CB . GLU A 1 218 ? 9.997 4.960 26.253 1.00 28.03 ? 218 GLU A CB 1 ATOM 1805 C CG . GLU A 1 218 ? 9.603 4.266 27.558 1.00 28.54 ? 218 GLU A CG 1 ATOM 1806 C CD . GLU A 1 218 ? 9.897 2.775 27.580 1.00 29.75 ? 218 GLU A CD 1 ATOM 1807 O OE1 . GLU A 1 218 ? 10.206 2.207 26.524 1.00 30.02 ? 218 GLU A OE1 1 ATOM 1808 O OE2 . GLU A 1 218 ? 9.824 2.162 28.662 1.00 30.41 ? 218 GLU A OE2 1 ATOM 1809 N N . ILE A 1 219 ? 11.529 7.871 25.227 1.00 27.72 ? 219 ILE A N 1 ATOM 1810 C CA . ILE A 1 219 ? 12.021 8.822 24.230 1.00 27.59 ? 219 ILE A CA 1 ATOM 1811 C C . ILE A 1 219 ? 13.378 8.416 23.662 1.00 27.35 ? 219 ILE A C 1 ATOM 1812 O O . ILE A 1 219 ? 14.311 8.158 24.418 1.00 27.41 ? 219 ILE A O 1 ATOM 1813 C CB . ILE A 1 219 ? 12.127 10.255 24.851 1.00 27.79 ? 219 ILE A CB 1 ATOM 1814 C CG1 . ILE A 1 219 ? 10.750 10.780 25.267 1.00 27.45 ? 219 ILE A CG1 1 ATOM 1815 C CG2 . ILE A 1 219 ? 12.786 11.229 23.894 1.00 27.86 ? 219 ILE A CG2 1 ATOM 1816 C CD1 . ILE A 1 219 ? 10.822 12.006 26.167 1.00 27.57 ? 219 ILE A CD1 1 ATOM 1817 N N . ARG A 1 220 ? 13.473 8.338 22.333 1.00 27.15 ? 220 ARG A N 1 ATOM 1818 C CA . ARG A 1 220 ? 14.763 8.212 21.643 1.00 26.94 ? 220 ARG A CA 1 ATOM 1819 C C . ARG A 1 220 ? 15.482 9.563 21.659 1.00 26.98 ? 220 ARG A C 1 ATOM 1820 O O . ARG A 1 220 ? 15.035 10.523 21.027 1.00 26.54 ? 220 ARG A O 1 ATOM 1821 C CB . ARG A 1 220 ? 14.582 7.755 20.193 1.00 26.96 ? 220 ARG A CB 1 ATOM 1822 C CG . ARG A 1 220 ? 14.773 6.265 19.929 1.00 26.49 ? 220 ARG A CG 1 ATOM 1823 C CD . ARG A 1 220 ? 13.588 5.460 20.395 1.00 25.65 ? 220 ARG A CD 1 ATOM 1824 N NE . ARG A 1 220 ? 13.478 4.165 19.728 1.00 23.66 ? 220 ARG A NE 1 ATOM 1825 C CZ . ARG A 1 220 ? 12.408 3.380 19.807 1.00 23.73 ? 220 ARG A CZ 1 ATOM 1826 N NH1 . ARG A 1 220 ? 11.367 3.744 20.540 1.00 22.35 ? 220 ARG A NH1 1 ATOM 1827 N NH2 . ARG A 1 220 ? 12.378 2.224 19.157 1.00 24.16 ? 220 ARG A NH2 1 ATOM 1828 N N . ALA A 1 221 ? 16.600 9.629 22.380 1.00 27.06 ? 221 ALA A N 1 ATOM 1829 C CA . ALA A 1 221 ? 17.295 10.890 22.597 1.00 27.32 ? 221 ALA A CA 1 ATOM 1830 C C . ALA A 1 221 ? 18.748 10.828 22.154 1.00 27.74 ? 221 ALA A C 1 ATOM 1831 O O . ALA A 1 221 ? 19.491 9.934 22.561 1.00 27.38 ? 221 ALA A O 1 ATOM 1832 C CB . ALA A 1 221 ? 17.199 11.294 24.062 1.00 26.94 ? 221 ALA A CB 1 ATOM 1833 N N . ARG A 1 222 ? 19.143 11.792 21.324 1.00 28.58 ? 222 ARG A N 1 ATOM 1834 C CA . ARG A 1 222 ? 20.525 11.906 20.843 1.00 29.57 ? 222 ARG A CA 1 ATOM 1835 C C . ARG A 1 222 ? 21.454 12.371 21.960 1.00 29.34 ? 222 ARG A C 1 ATOM 1836 O O . ARG A 1 222 ? 22.660 12.111 21.922 1.00 29.29 ? 222 ARG A O 1 ATOM 1837 C CB . ARG A 1 222 ? 20.618 12.903 19.690 1.00 29.89 ? 222 ARG A CB 1 ATOM 1838 C CG . ARG A 1 222 ? 19.881 12.555 18.388 1.00 33.41 ? 222 ARG A CG 1 ATOM 1839 C CD . ARG A 1 222 ? 20.654 11.635 17.422 1.00 40.07 ? 222 ARG A CD 1 ATOM 1840 N NE . ARG A 1 222 ? 22.115 11.605 17.600 1.00 45.97 ? 222 ARG A NE 1 ATOM 1841 C CZ . ARG A 1 222 ? 22.986 12.468 17.067 1.00 48.94 ? 222 ARG A CZ 1 ATOM 1842 N NH1 . ARG A 1 222 ? 22.572 13.488 16.320 1.00 50.53 ? 222 ARG A NH1 1 ATOM 1843 N NH2 . ARG A 1 222 ? 24.288 12.314 17.302 1.00 49.90 ? 222 ARG A NH2 1 ATOM 1844 N N . LEU A 1 223 ? 20.878 13.055 22.950 1.00 29.35 ? 223 LEU A N 1 ATOM 1845 C CA . LEU A 1 223 ? 21.617 13.641 24.076 1.00 29.36 ? 223 LEU A CA 1 ATOM 1846 C C . LEU A 1 223 ? 22.746 14.544 23.598 1.00 29.78 ? 223 LEU A C 1 ATOM 1847 O O . LEU A 1 223 ? 23.882 14.438 24.075 1.00 29.75 ? 223 LEU A O 1 ATOM 1848 C CB . LEU A 1 223 ? 22.161 12.564 25.020 1.00 29.12 ? 223 LEU A CB 1 ATOM 1849 C CG . LEU A 1 223 ? 21.222 11.548 25.677 1.00 28.77 ? 223 LEU A CG 1 ATOM 1850 C CD1 . LEU A 1 223 ? 22.050 10.555 26.475 1.00 28.00 ? 223 LEU A CD1 1 ATOM 1851 C CD2 . LEU A 1 223 ? 20.157 12.215 26.565 1.00 27.43 ? 223 LEU A CD2 1 ATOM 1852 N N . LEU A 1 224 ? 22.423 15.425 22.647 1.00 30.09 ? 224 LEU A N 1 ATOM 1853 C CA . LEU A 1 224 ? 23.374 16.398 22.113 1.00 30.48 ? 224 LEU A CA 1 ATOM 1854 C C . LEU A 1 224 ? 23.730 17.362 23.245 1.00 30.78 ? 224 LEU A C 1 ATOM 1855 O O . LEU A 1 224 ? 22.943 17.522 24.173 1.00 31.03 ? 224 LEU A O 1 ATOM 1856 C CB . LEU A 1 224 ? 22.762 17.156 20.921 1.00 30.34 ? 224 LEU A CB 1 ATOM 1857 C CG . LEU A 1 224 ? 22.737 16.627 19.464 1.00 30.50 ? 224 LEU A CG 1 ATOM 1858 C CD1 . LEU A 1 224 ? 24.078 16.744 18.784 1.00 31.13 ? 224 LEU A CD1 1 ATOM 1859 C CD2 . LEU A 1 224 ? 22.315 15.213 19.361 1.00 30.67 ? 224 LEU A CD2 1 ATOM 1860 N N . PRO A 1 225 ? 24.917 17.994 23.190 1.00 31.14 ? 225 PRO A N 1 ATOM 1861 C CA . PRO A 1 225 ? 25.287 18.886 24.300 1.00 31.38 ? 225 PRO A CA 1 ATOM 1862 C C . PRO A 1 225 ? 24.318 20.057 24.504 1.00 31.72 ? 225 PRO A C 1 ATOM 1863 O O . PRO A 1 225 ? 23.968 20.754 23.549 1.00 31.93 ? 225 PRO A O 1 ATOM 1864 C CB . PRO A 1 225 ? 26.687 19.383 23.918 1.00 31.24 ? 225 PRO A CB 1 ATOM 1865 C CG . PRO A 1 225 ? 26.890 18.987 22.490 1.00 31.36 ? 225 PRO A CG 1 ATOM 1866 C CD . PRO A 1 225 ? 26.019 17.815 22.226 1.00 31.01 ? 225 PRO A CD 1 ATOM 1867 N N . VAL A 1 226 ? 23.877 20.235 25.748 1.00 31.99 ? 226 VAL A N 1 ATOM 1868 C CA . VAL A 1 226 ? 23.036 21.366 26.148 1.00 32.10 ? 226 VAL A CA 1 ATOM 1869 C C . VAL A 1 226 ? 23.983 22.480 26.607 1.00 32.23 ? 226 VAL A C 1 ATOM 1870 O O . VAL A 1 226 ? 25.018 22.202 27.225 1.00 31.92 ? 226 VAL A O 1 ATOM 1871 C CB . VAL A 1 226 ? 22.006 20.960 27.258 1.00 32.13 ? 226 VAL A CB 1 ATOM 1872 C CG1 . VAL A 1 226 ? 21.143 22.139 27.692 1.00 32.00 ? 226 VAL A CG1 1 ATOM 1873 C CG2 . VAL A 1 226 ? 21.114 19.826 26.771 1.00 31.95 ? 226 VAL A CG2 1 ATOM 1874 N N . TYR A 1 227 ? 23.649 23.727 26.276 1.00 32.43 ? 227 TYR A N 1 ATOM 1875 C CA . TYR A 1 227 ? 24.583 24.843 26.476 1.00 32.76 ? 227 TYR A CA 1 ATOM 1876 C C . TYR A 1 227 ? 23.995 26.021 27.263 1.00 33.34 ? 227 TYR A C 1 ATOM 1877 O O . TYR A 1 227 ? 22.771 26.183 27.351 1.00 33.38 ? 227 TYR A O 1 ATOM 1878 C CB . TYR A 1 227 ? 25.172 25.310 25.130 1.00 32.33 ? 227 TYR A CB 1 ATOM 1879 C CG . TYR A 1 227 ? 24.181 26.010 24.222 1.00 31.89 ? 227 TYR A CG 1 ATOM 1880 C CD1 . TYR A 1 227 ? 24.063 27.401 24.234 1.00 31.00 ? 227 TYR A CD1 1 ATOM 1881 C CD2 . TYR A 1 227 ? 23.363 25.286 23.353 1.00 30.58 ? 227 TYR A CD2 1 ATOM 1882 C CE1 . TYR A 1 227 ? 23.157 28.054 23.410 1.00 31.23 ? 227 TYR A CE1 1 ATOM 1883 C CE2 . TYR A 1 227 ? 22.446 25.934 22.521 1.00 31.12 ? 227 TYR A CE2 1 ATOM 1884 C CZ . TYR A 1 227 ? 22.353 27.319 22.557 1.00 31.53 ? 227 TYR A CZ 1 ATOM 1885 O OH . TYR A 1 227 ? 21.457 27.974 21.749 1.00 31.43 ? 227 TYR A OH 1 ATOM 1886 N N . GLU A 1 228 ? 24.886 26.838 27.823 1.00 34.07 ? 228 GLU A N 1 ATOM 1887 C CA . GLU A 1 228 ? 24.505 27.998 28.627 1.00 34.91 ? 228 GLU A CA 1 ATOM 1888 C C . GLU A 1 228 ? 24.824 29.298 27.884 1.00 35.90 ? 228 GLU A C 1 ATOM 1889 O O . GLU A 1 228 ? 25.497 29.272 26.849 1.00 35.96 ? 228 GLU A O 1 ATOM 1890 C CB . GLU A 1 228 ? 25.235 27.963 29.975 1.00 34.59 ? 228 GLU A CB 1 ATOM 1891 C CG . GLU A 1 228 ? 25.056 26.665 30.768 1.00 33.57 ? 228 GLU A CG 1 ATOM 1892 C CD . GLU A 1 228 ? 23.710 26.575 31.474 1.00 32.84 ? 228 GLU A CD 1 ATOM 1893 O OE1 . GLU A 1 228 ? 22.898 27.517 31.367 1.00 30.35 ? 228 GLU A OE1 1 ATOM 1894 O OE2 . GLU A 1 228 ? 23.464 25.551 32.152 1.00 34.92 ? 228 GLU A OE2 1 ATOM 1895 N N . LEU A 1 229 ? 24.351 30.430 28.412 1.00 37.24 ? 229 LEU A N 1 ATOM 1896 C CA . LEU A 1 229 ? 24.654 31.747 27.823 1.00 38.58 ? 229 LEU A CA 1 ATOM 1897 C C . LEU A 1 229 ? 26.153 32.035 27.747 1.00 39.56 ? 229 LEU A C 1 ATOM 1898 O O . LEU A 1 229 ? 26.606 32.664 26.802 1.00 39.87 ? 229 LEU A O 1 ATOM 1899 C CB . LEU A 1 229 ? 23.956 32.874 28.583 1.00 38.42 ? 229 LEU A CB 1 ATOM 1900 C CG . LEU A 1 229 ? 22.502 33.227 28.293 1.00 38.26 ? 229 LEU A CG 1 ATOM 1901 C CD1 . LEU A 1 229 ? 22.122 34.449 29.102 1.00 37.34 ? 229 LEU A CD1 1 ATOM 1902 C CD2 . LEU A 1 229 ? 22.264 33.476 26.809 1.00 38.71 ? 229 LEU A CD2 1 ATOM 1903 N N . SER A 1 230 ? 26.904 31.573 28.746 1.00 40.72 ? 230 SER A N 1 ATOM 1904 C CA . SER A 1 230 ? 28.360 31.686 28.778 1.00 41.82 ? 230 SER A CA 1 ATOM 1905 C C . SER A 1 230 ? 29.014 31.031 27.564 1.00 42.35 ? 230 SER A C 1 ATOM 1906 O O . SER A 1 230 ? 30.031 31.507 27.058 1.00 42.65 ? 230 SER A O 1 ATOM 1907 C CB . SER A 1 230 ? 28.909 31.038 30.051 1.00 41.89 ? 230 SER A CB 1 ATOM 1908 O OG . SER A 1 230 ? 28.436 29.707 30.185 1.00 42.82 ? 230 SER A OG 1 ATOM 1909 N N . GLY A 1 231 ? 28.420 29.936 27.102 1.00 42.94 ? 231 GLY A N 1 ATOM 1910 C CA . GLY A 1 231 ? 28.988 29.139 26.026 1.00 43.02 ? 231 GLY A CA 1 ATOM 1911 C C . GLY A 1 231 ? 29.451 27.773 26.494 1.00 43.28 ? 231 GLY A C 1 ATOM 1912 O O . GLY A 1 231 ? 29.918 26.973 25.679 1.00 43.25 ? 231 GLY A O 1 ATOM 1913 N N . GLU A 1 232 ? 29.326 27.506 27.801 1.00 43.53 ? 232 GLU A N 1 ATOM 1914 C CA . GLU A 1 232 ? 29.666 26.192 28.377 1.00 43.74 ? 232 GLU A CA 1 ATOM 1915 C C . GLU A 1 232 ? 28.717 25.106 27.848 1.00 43.26 ? 232 GLU A C 1 ATOM 1916 O O . GLU A 1 232 ? 27.533 25.360 27.626 1.00 43.08 ? 232 GLU A O 1 ATOM 1917 C CB . GLU A 1 232 ? 29.695 26.229 29.922 1.00 43.97 ? 232 GLU A CB 1 ATOM 1918 C CG . GLU A 1 232 ? 28.660 25.345 30.637 1.00 46.25 ? 232 GLU A CG 1 ATOM 1919 C CD . GLU A 1 232 ? 29.050 24.967 32.078 1.00 48.98 ? 232 GLU A CD 1 ATOM 1920 O OE1 . GLU A 1 232 ? 29.016 25.856 32.967 1.00 49.50 ? 232 GLU A OE1 1 ATOM 1921 O OE2 . GLU A 1 232 ? 29.363 23.773 32.318 1.00 49.71 ? 232 GLU A OE2 1 ATOM 1922 N N . HIS A 1 233 ? 29.262 23.912 27.620 1.00 42.85 ? 233 HIS A N 1 ATOM 1923 C CA . HIS A 1 233 ? 28.491 22.774 27.136 1.00 42.57 ? 233 HIS A CA 1 ATOM 1924 C C . HIS A 1 233 ? 28.380 21.745 28.257 1.00 41.34 ? 233 HIS A C 1 ATOM 1925 O O . HIS A 1 233 ? 29.342 21.517 28.988 1.00 41.08 ? 233 HIS A O 1 ATOM 1926 C CB . HIS A 1 233 ? 29.172 22.144 25.910 1.00 43.27 ? 233 HIS A CB 1 ATOM 1927 C CG . HIS A 1 233 ? 29.061 22.962 24.655 1.00 46.77 ? 233 HIS A CG 1 ATOM 1928 N ND1 . HIS A 1 233 ? 29.122 22.402 23.394 1.00 49.94 ? 233 HIS A ND1 1 ATOM 1929 C CD2 . HIS A 1 233 ? 28.887 24.294 24.463 1.00 49.55 ? 233 HIS A CD2 1 ATOM 1930 C CE1 . HIS A 1 233 ? 28.992 23.351 22.482 1.00 50.56 ? 233 HIS A CE1 1 ATOM 1931 N NE2 . HIS A 1 233 ? 28.847 24.508 23.105 1.00 50.72 ? 233 HIS A NE2 1 ATOM 1932 N N . HIS A 1 234 ? 27.205 21.141 28.401 1.00 40.04 ? 234 HIS A N 1 ATOM 1933 C CA . HIS A 1 234 ? 27.031 20.020 29.319 1.00 38.98 ? 234 HIS A CA 1 ATOM 1934 C C . HIS A 1 234 ? 27.215 18.690 28.584 1.00 38.25 ? 234 HIS A C 1 ATOM 1935 O O . HIS A 1 234 ? 27.280 18.655 27.359 1.00 38.10 ? 234 HIS A O 1 ATOM 1936 C CB . HIS A 1 234 ? 25.661 20.076 29.983 1.00 38.93 ? 234 HIS A CB 1 ATOM 1937 C CG . HIS A 1 234 ? 25.445 21.297 30.823 1.00 39.54 ? 234 HIS A CG 1 ATOM 1938 N ND1 . HIS A 1 234 ? 26.074 21.486 32.033 1.00 40.15 ? 234 HIS A ND1 1 ATOM 1939 C CD2 . HIS A 1 234 ? 24.654 22.382 30.634 1.00 39.97 ? 234 HIS A CD2 1 ATOM 1940 C CE1 . HIS A 1 234 ? 25.685 22.637 32.552 1.00 40.05 ? 234 HIS A CE1 1 ATOM 1941 N NE2 . HIS A 1 234 ? 24.825 23.200 31.723 1.00 40.07 ? 234 HIS A NE2 1 ATOM 1942 N N . ASP A 1 235 ? 27.300 17.597 29.331 1.00 37.55 ? 235 ASP A N 1 ATOM 1943 C CA . ASP A 1 235 ? 27.505 16.290 28.722 1.00 37.19 ? 235 ASP A CA 1 ATOM 1944 C C . ASP A 1 235 ? 26.267 15.384 28.807 1.00 37.05 ? 235 ASP A C 1 ATOM 1945 O O . ASP A 1 235 ? 25.221 15.798 29.312 1.00 36.90 ? 235 ASP A O 1 ATOM 1946 C CB . ASP A 1 235 ? 28.763 15.609 29.301 1.00 36.99 ? 235 ASP A CB 1 ATOM 1947 C CG . ASP A 1 235 ? 28.624 15.231 30.778 1.00 37.02 ? 235 ASP A CG 1 ATOM 1948 O OD1 . ASP A 1 235 ? 27.520 15.329 31.370 1.00 36.86 ? 235 ASP A OD1 1 ATOM 1949 O OD2 . ASP A 1 235 ? 29.648 14.809 31.352 1.00 37.81 ? 235 ASP A OD2 1 ATOM 1950 N N . GLU A 1 236 ? 26.408 14.155 28.310 1.00 37.01 ? 236 GLU A N 1 ATOM 1951 C CA . GLU A 1 236 ? 25.325 13.167 28.286 1.00 37.34 ? 236 GLU A CA 1 ATOM 1952 C C . GLU A 1 236 ? 24.731 12.893 29.671 1.00 37.37 ? 236 GLU A C 1 ATOM 1953 O O . GLU A 1 236 ? 23.509 12.894 29.831 1.00 37.39 ? 236 GLU A O 1 ATOM 1954 C CB . GLU A 1 236 ? 25.796 11.858 27.636 1.00 37.30 ? 236 GLU A CB 1 ATOM 1955 C CG . GLU A 1 236 ? 26.122 11.965 26.147 1.00 38.41 ? 236 GLU A CG 1 ATOM 1956 C CD . GLU A 1 236 ? 27.534 12.482 25.843 1.00 40.14 ? 236 GLU A CD 1 ATOM 1957 O OE1 . GLU A 1 236 ? 28.372 12.618 26.766 1.00 40.44 ? 236 GLU A OE1 1 ATOM 1958 O OE2 . GLU A 1 236 ? 27.810 12.748 24.656 1.00 41.64 ? 236 GLU A OE2 1 ATOM 1959 N N . GLU A 1 237 ? 25.598 12.663 30.661 1.00 37.57 ? 237 GLU A N 1 ATOM 1960 C CA . GLU A 1 237 ? 25.180 12.478 32.053 1.00 37.79 ? 237 GLU A CA 1 ATOM 1961 C C . GLU A 1 237 ? 24.250 13.592 32.503 1.00 36.54 ? 237 GLU A C 1 ATOM 1962 O O . GLU A 1 237 ? 23.193 13.328 33.082 1.00 36.66 ? 237 GLU A O 1 ATOM 1963 C CB . GLU A 1 237 ? 26.385 12.433 32.999 1.00 38.54 ? 237 GLU A CB 1 ATOM 1964 C CG . GLU A 1 237 ? 26.959 11.044 33.256 1.00 43.41 ? 237 GLU A CG 1 ATOM 1965 C CD . GLU A 1 237 ? 28.197 10.723 32.404 1.00 50.22 ? 237 GLU A CD 1 ATOM 1966 O OE1 . GLU A 1 237 ? 28.745 11.641 31.738 1.00 52.80 ? 237 GLU A OE1 1 ATOM 1967 O OE2 . GLU A 1 237 ? 28.629 9.541 32.408 1.00 52.70 ? 237 GLU A OE2 1 ATOM 1968 N N . TRP A 1 238 ? 24.657 14.830 32.231 1.00 35.15 ? 238 TRP A N 1 ATOM 1969 C CA . TRP A 1 238 ? 23.897 16.021 32.610 1.00 33.82 ? 238 TRP A CA 1 ATOM 1970 C C . TRP A 1 238 ? 22.494 16.046 31.974 1.00 33.09 ? 238 TRP A C 1 ATOM 1971 O O . TRP A 1 238 ? 21.522 16.458 32.628 1.00 32.93 ? 238 TRP A O 1 ATOM 1972 C CB . TRP A 1 238 ? 24.691 17.287 32.256 1.00 33.61 ? 238 TRP A CB 1 ATOM 1973 C CG . TRP A 1 238 ? 24.104 18.558 32.790 1.00 33.04 ? 238 TRP A CG 1 ATOM 1974 C CD1 . TRP A 1 238 ? 24.477 19.217 33.927 1.00 32.12 ? 238 TRP A CD1 1 ATOM 1975 C CD2 . TRP A 1 238 ? 23.047 19.331 32.204 1.00 32.70 ? 238 TRP A CD2 1 ATOM 1976 N NE1 . TRP A 1 238 ? 23.716 20.346 34.089 1.00 32.18 ? 238 TRP A NE1 1 ATOM 1977 C CE2 . TRP A 1 238 ? 22.829 20.442 33.047 1.00 32.67 ? 238 TRP A CE2 1 ATOM 1978 C CE3 . TRP A 1 238 ? 22.262 19.195 31.045 1.00 32.53 ? 238 TRP A CE3 1 ATOM 1979 C CZ2 . TRP A 1 238 ? 21.855 21.417 32.769 1.00 32.42 ? 238 TRP A CZ2 1 ATOM 1980 C CZ3 . TRP A 1 238 ? 21.293 20.161 30.770 1.00 32.22 ? 238 TRP A CZ3 1 ATOM 1981 C CH2 . TRP A 1 238 ? 21.101 21.258 31.629 1.00 32.20 ? 238 TRP A CH2 1 ATOM 1982 N N . SER A 1 239 ? 22.389 15.608 30.715 1.00 31.79 ? 239 SER A N 1 ATOM 1983 C CA . SER A 1 239 ? 21.091 15.566 30.026 1.00 30.93 ? 239 SER A CA 1 ATOM 1984 C C . SER A 1 239 ? 20.156 14.522 30.624 1.00 30.60 ? 239 SER A C 1 ATOM 1985 O O . SER A 1 239 ? 18.961 14.773 30.781 1.00 30.14 ? 239 SER A O 1 ATOM 1986 C CB . SER A 1 239 ? 21.261 15.332 28.527 1.00 30.73 ? 239 SER A CB 1 ATOM 1987 O OG . SER A 1 239 ? 21.588 16.534 27.855 1.00 29.89 ? 239 SER A OG 1 ATOM 1988 N N . VAL A 1 240 ? 20.711 13.361 30.973 1.00 30.50 ? 240 VAL A N 1 ATOM 1989 C CA . VAL A 1 240 ? 19.933 12.279 31.582 1.00 30.59 ? 240 VAL A CA 1 ATOM 1990 C C . VAL A 1 240 ? 19.467 12.676 32.983 1.00 30.84 ? 240 VAL A C 1 ATOM 1991 O O . VAL A 1 240 ? 18.343 12.376 33.377 1.00 30.79 ? 240 VAL A O 1 ATOM 1992 C CB . VAL A 1 240 ? 20.724 10.945 31.632 1.00 30.63 ? 240 VAL A CB 1 ATOM 1993 C CG1 . VAL A 1 240 ? 19.913 9.844 32.334 1.00 29.98 ? 240 VAL A CG1 1 ATOM 1994 C CG2 . VAL A 1 240 ? 21.123 10.498 30.223 1.00 30.33 ? 240 VAL A CG2 1 ATOM 1995 N N . LYS A 1 241 ? 20.335 13.363 33.719 1.00 31.23 ? 241 LYS A N 1 ATOM 1996 C CA . LYS A 1 241 ? 20.001 13.865 35.043 1.00 31.83 ? 241 LYS A CA 1 ATOM 1997 C C . LYS A 1 241 ? 18.828 14.828 34.946 1.00 31.35 ? 241 LYS A C 1 ATOM 1998 O O . LYS A 1 241 ? 17.866 14.724 35.702 1.00 31.12 ? 241 LYS A O 1 ATOM 1999 C CB . LYS A 1 241 ? 21.211 14.575 35.656 1.00 32.57 ? 241 LYS A CB 1 ATOM 2000 C CG . LYS A 1 241 ? 21.074 14.913 37.151 1.00 35.32 ? 241 LYS A CG 1 ATOM 2001 C CD . LYS A 1 241 ? 21.895 13.951 38.009 1.00 40.13 ? 241 LYS A CD 1 ATOM 2002 C CE . LYS A 1 241 ? 23.405 14.172 37.815 1.00 42.39 ? 241 LYS A CE 1 ATOM 2003 N NZ . LYS A 1 241 ? 24.196 13.013 38.328 1.00 44.06 ? 241 LYS A NZ 1 ATOM 2004 N N . THR A 1 242 ? 18.926 15.752 33.994 1.00 31.35 ? 242 THR A N 1 ATOM 2005 C CA . THR A 1 242 ? 17.899 16.750 33.726 1.00 31.34 ? 242 THR A CA 1 ATOM 2006 C C . THR A 1 242 ? 16.557 16.123 33.325 1.00 31.90 ? 242 THR A C 1 ATOM 2007 O O . THR A 1 242 ? 15.509 16.541 33.825 1.00 32.10 ? 242 THR A O 1 ATOM 2008 C CB . THR A 1 242 ? 18.393 17.745 32.662 1.00 31.24 ? 242 THR A CB 1 ATOM 2009 O OG1 . THR A 1 242 ? 19.617 18.336 33.114 1.00 30.44 ? 242 THR A OG1 1 ATOM 2010 C CG2 . THR A 1 242 ? 17.369 18.844 32.401 1.00 30.98 ? 242 THR A CG2 1 ATOM 2011 N N . TYR A 1 243 ? 16.589 15.113 32.453 1.00 32.31 ? 243 TYR A N 1 ATOM 2012 C CA . TYR A 1 243 ? 15.362 14.421 32.052 1.00 32.88 ? 243 TYR A CA 1 ATOM 2013 C C . TYR A 1 243 ? 14.675 13.850 33.279 1.00 33.38 ? 243 TYR A C 1 ATOM 2014 O O . TYR A 1 243 ? 13.480 14.072 33.484 1.00 33.49 ? 243 TYR A O 1 ATOM 2015 C CB . TYR A 1 243 ? 15.631 13.297 31.044 1.00 32.62 ? 243 TYR A CB 1 ATOM 2016 C CG . TYR A 1 243 ? 15.674 13.705 29.586 1.00 32.39 ? 243 TYR A CG 1 ATOM 2017 C CD1 . TYR A 1 243 ? 14.527 14.160 28.915 1.00 32.45 ? 243 TYR A CD1 1 ATOM 2018 C CD2 . TYR A 1 243 ? 16.859 13.590 28.856 1.00 32.35 ? 243 TYR A CD2 1 ATOM 2019 C CE1 . TYR A 1 243 ? 14.581 14.512 27.552 1.00 31.80 ? 243 TYR A CE1 1 ATOM 2020 C CE2 . TYR A 1 243 ? 16.923 13.937 27.499 1.00 31.17 ? 243 TYR A CE2 1 ATOM 2021 C CZ . TYR A 1 243 ? 15.790 14.392 26.858 1.00 31.23 ? 243 TYR A CZ 1 ATOM 2022 O OH . TYR A 1 243 ? 15.886 14.727 25.531 1.00 30.40 ? 243 TYR A OH 1 ATOM 2023 N N . GLN A 1 244 ? 15.443 13.124 34.089 1.00 34.07 ? 244 GLN A N 1 ATOM 2024 C CA . GLN A 1 244 ? 14.965 12.558 35.350 1.00 35.02 ? 244 GLN A CA 1 ATOM 2025 C C . GLN A 1 244 ? 14.367 13.638 36.257 1.00 35.32 ? 244 GLN A C 1 ATOM 2026 O O . GLN A 1 244 ? 13.249 13.486 36.755 1.00 35.34 ? 244 GLN A O 1 ATOM 2027 C CB . GLN A 1 244 ? 16.110 11.822 36.062 1.00 35.29 ? 244 GLN A CB 1 ATOM 2028 C CG . GLN A 1 244 ? 15.736 11.189 37.404 1.00 36.80 ? 244 GLN A CG 1 ATOM 2029 C CD . GLN A 1 244 ? 16.859 10.354 38.012 1.00 39.13 ? 244 GLN A CD 1 ATOM 2030 O OE1 . GLN A 1 244 ? 18.030 10.741 37.993 1.00 40.74 ? 244 GLN A OE1 1 ATOM 2031 N NE2 . GLN A 1 244 ? 16.501 9.200 38.562 1.00 39.84 ? 244 GLN A NE2 1 ATOM 2032 N N . GLU A 1 245 ? 15.115 14.729 36.443 1.00 35.73 ? 245 GLU A N 1 ATOM 2033 C CA . GLU A 1 245 ? 14.712 15.830 37.319 1.00 36.03 ? 245 GLU A CA 1 ATOM 2034 C C . GLU A 1 245 ? 13.432 16.529 36.878 1.00 35.65 ? 245 GLU A C 1 ATOM 2035 O O . GLU A 1 245 ? 12.545 16.758 37.703 1.00 35.65 ? 245 GLU A O 1 ATOM 2036 C CB . GLU A 1 245 ? 15.838 16.850 37.463 1.00 36.47 ? 245 GLU A CB 1 ATOM 2037 C CG . GLU A 1 245 ? 16.927 16.428 38.437 1.00 39.28 ? 245 GLU A CG 1 ATOM 2038 C CD . GLU A 1 245 ? 18.050 17.447 38.555 1.00 43.20 ? 245 GLU A CD 1 ATOM 2039 O OE1 . GLU A 1 245 ? 17.859 18.607 38.118 1.00 44.18 ? 245 GLU A OE1 1 ATOM 2040 O OE2 . GLU A 1 245 ? 19.125 17.084 39.093 1.00 45.13 ? 245 GLU A OE2 1 ATOM 2041 N N . VAL A 1 246 ? 13.336 16.867 35.590 1.00 35.20 ? 246 VAL A N 1 ATOM 2042 C CA . VAL A 1 246 ? 12.147 17.541 35.062 1.00 34.61 ? 246 VAL A CA 1 ATOM 2043 C C . VAL A 1 246 ? 10.920 16.619 35.159 1.00 34.57 ? 246 VAL A C 1 ATOM 2044 O O . VAL A 1 246 ? 9.828 17.058 35.526 1.00 34.15 ? 246 VAL A O 1 ATOM 2045 C CB . VAL A 1 246 ? 12.371 18.056 33.619 1.00 34.52 ? 246 VAL A CB 1 ATOM 2046 C CG1 . VAL A 1 246 ? 11.144 18.811 33.110 1.00 34.20 ? 246 VAL A CG1 1 ATOM 2047 C CG2 . VAL A 1 246 ? 13.579 18.974 33.576 1.00 34.35 ? 246 VAL A CG2 1 ATOM 2048 N N . ALA A 1 247 ? 11.123 15.338 34.859 1.00 34.73 ? 247 ALA A N 1 ATOM 2049 C CA . ALA A 1 247 ? 10.062 14.336 34.957 1.00 35.15 ? 247 ALA A CA 1 ATOM 2050 C C . ALA A 1 247 ? 9.562 14.171 36.393 1.00 35.32 ? 247 ALA A C 1 ATOM 2051 O O . ALA A 1 247 ? 8.359 14.016 36.605 1.00 35.32 ? 247 ALA A O 1 ATOM 2052 C CB . ALA A 1 247 ? 10.517 12.992 34.375 1.00 34.86 ? 247 ALA A CB 1 ATOM 2053 N N . GLN A 1 248 ? 10.481 14.210 37.361 1.00 35.47 ? 248 GLN A N 1 ATOM 2054 C CA . GLN A 1 248 ? 10.117 14.191 38.782 1.00 36.02 ? 248 GLN A CA 1 ATOM 2055 C C . GLN A 1 248 ? 9.274 15.406 39.152 1.00 35.89 ? 248 GLN A C 1 ATOM 2056 O O . GLN A 1 248 ? 8.235 15.276 39.804 1.00 35.94 ? 248 GLN A O 1 ATOM 2057 C CB . GLN A 1 248 ? 11.360 14.096 39.674 1.00 36.09 ? 248 GLN A CB 1 ATOM 2058 C CG . GLN A 1 248 ? 11.764 12.664 39.988 1.00 38.01 ? 248 GLN A CG 1 ATOM 2059 C CD . GLN A 1 248 ? 13.272 12.463 40.146 1.00 41.22 ? 248 GLN A CD 1 ATOM 2060 O OE1 . GLN A 1 248 ? 14.036 13.416 40.353 1.00 42.55 ? 248 GLN A OE1 1 ATOM 2061 N NE2 . GLN A 1 248 ? 13.706 11.207 40.052 1.00 41.96 ? 248 GLN A NE2 1 ATOM 2062 N N . LYS A 1 249 ? 9.718 16.578 38.708 1.00 35.81 ? 249 LYS A N 1 ATOM 2063 C CA . LYS A 1 249 ? 8.998 17.830 38.919 1.00 36.12 ? 249 LYS A CA 1 ATOM 2064 C C . LYS A 1 249 ? 7.587 17.769 38.325 1.00 35.72 ? 249 LYS A C 1 ATOM 2065 O O . LYS A 1 249 ? 6.628 18.276 38.920 1.00 35.96 ? 249 LYS A O 1 ATOM 2066 C CB . LYS A 1 249 ? 9.805 18.991 38.327 1.00 36.52 ? 249 LYS A CB 1 ATOM 2067 C CG . LYS A 1 249 ? 9.140 20.369 38.338 1.00 39.24 ? 249 LYS A CG 1 ATOM 2068 C CD . LYS A 1 249 ? 8.996 20.949 39.745 1.00 43.65 ? 249 LYS A CD 1 ATOM 2069 C CE . LYS A 1 249 ? 9.520 22.381 39.792 1.00 45.88 ? 249 LYS A CE 1 ATOM 2070 N NZ . LYS A 1 249 ? 9.088 23.117 41.026 1.00 47.51 ? 249 LYS A NZ 1 ATOM 2071 N N . PHE A 1 250 ? 7.463 17.132 37.163 1.00 35.03 ? 250 PHE A N 1 ATOM 2072 C CA . PHE A 1 250 ? 6.177 17.006 36.492 1.00 34.23 ? 250 PHE A CA 1 ATOM 2073 C C . PHE A 1 250 ? 5.247 16.055 37.243 1.00 34.84 ? 250 PHE A C 1 ATOM 2074 O O . PHE A 1 250 ? 4.061 16.352 37.421 1.00 34.50 ? 250 PHE A O 1 ATOM 2075 C CB . PHE A 1 250 ? 6.349 16.556 35.032 1.00 33.39 ? 250 PHE A CB 1 ATOM 2076 C CG . PHE A 1 250 ? 5.071 16.578 34.241 1.00 30.87 ? 250 PHE A CG 1 ATOM 2077 C CD1 . PHE A 1 250 ? 4.635 17.744 33.623 1.00 28.56 ? 250 PHE A CD1 1 ATOM 2078 C CD2 . PHE A 1 250 ? 4.291 15.436 34.127 1.00 28.58 ? 250 PHE A CD2 1 ATOM 2079 C CE1 . PHE A 1 250 ? 3.443 17.764 32.903 1.00 27.75 ? 250 PHE A CE1 1 ATOM 2080 C CE2 . PHE A 1 250 ? 3.095 15.450 33.406 1.00 27.22 ? 250 PHE A CE2 1 ATOM 2081 C CZ . PHE A 1 250 ? 2.670 16.613 32.796 1.00 26.51 ? 250 PHE A CZ 1 ATOM 2082 N N . VAL A 1 251 ? 5.792 14.919 37.677 1.00 35.54 ? 251 VAL A N 1 ATOM 2083 C CA . VAL A 1 251 ? 5.014 13.890 38.375 1.00 36.67 ? 251 VAL A CA 1 ATOM 2084 C C . VAL A 1 251 ? 4.527 14.392 39.741 1.00 37.79 ? 251 VAL A C 1 ATOM 2085 O O . VAL A 1 251 ? 3.497 13.946 40.243 1.00 37.92 ? 251 VAL A O 1 ATOM 2086 C CB . VAL A 1 251 ? 5.805 12.542 38.486 1.00 36.52 ? 251 VAL A CB 1 ATOM 2087 C CG1 . VAL A 1 251 ? 5.185 11.594 39.502 1.00 35.68 ? 251 VAL A CG1 1 ATOM 2088 C CG2 . VAL A 1 251 ? 5.882 11.862 37.128 1.00 36.32 ? 251 VAL A CG2 1 ATOM 2089 N N . GLU A 1 252 ? 5.266 15.341 40.313 1.00 39.26 ? 252 GLU A N 1 ATOM 2090 C CA . GLU A 1 252 ? 4.905 15.967 41.581 1.00 40.58 ? 252 GLU A CA 1 ATOM 2091 C C . GLU A 1 252 ? 3.619 16.789 41.504 1.00 40.78 ? 252 GLU A C 1 ATOM 2092 O O . GLU A 1 252 ? 2.876 16.858 42.477 1.00 40.89 ? 252 GLU A O 1 ATOM 2093 C CB . GLU A 1 252 ? 6.055 16.824 42.089 1.00 40.92 ? 252 GLU A CB 1 ATOM 2094 C CG . GLU A 1 252 ? 7.031 16.060 42.949 1.00 43.46 ? 252 GLU A CG 1 ATOM 2095 C CD . GLU A 1 252 ? 8.383 16.750 43.084 1.00 47.56 ? 252 GLU A CD 1 ATOM 2096 O OE1 . GLU A 1 252 ? 8.472 17.997 42.917 1.00 48.45 ? 252 GLU A OE1 1 ATOM 2097 O OE2 . GLU A 1 252 ? 9.368 16.028 43.364 1.00 48.91 ? 252 GLU A OE2 1 ATOM 2098 N N . THR A 1 253 ? 3.357 17.401 40.352 1.00 41.13 ? 253 THR A N 1 ATOM 2099 C CA . THR A 1 253 ? 2.138 18.185 40.171 1.00 41.58 ? 253 THR A CA 1 ATOM 2100 C C . THR A 1 253 ? 1.128 17.477 39.271 1.00 41.47 ? 253 THR A C 1 ATOM 2101 O O . THR A 1 253 ? 0.099 18.042 38.910 1.00 41.65 ? 253 THR A O 1 ATOM 2102 C CB . THR A 1 253 ? 2.432 19.595 39.636 1.00 41.68 ? 253 THR A CB 1 ATOM 2103 O OG1 . THR A 1 253 ? 3.109 19.502 38.379 1.00 42.67 ? 253 THR A OG1 1 ATOM 2104 C CG2 . THR A 1 253 ? 3.293 20.369 40.629 1.00 42.01 ? 253 THR A CG2 1 ATOM 2105 N N . HIS A 1 254 ? 1.442 16.239 38.903 1.00 41.36 ? 254 HIS A N 1 ATOM 2106 C CA . HIS A 1 254 ? 0.545 15.388 38.127 1.00 40.90 ? 254 HIS A CA 1 ATOM 2107 C C . HIS A 1 254 ? 0.768 13.957 38.612 1.00 41.23 ? 254 HIS A C 1 ATOM 2108 O O . HIS A 1 254 ? 1.464 13.178 37.956 1.00 41.21 ? 254 HIS A O 1 ATOM 2109 C CB . HIS A 1 254 ? 0.831 15.486 36.624 1.00 40.46 ? 254 HIS A CB 1 ATOM 2110 C CG . HIS A 1 254 ? 0.811 16.883 36.081 1.00 38.99 ? 254 HIS A CG 1 ATOM 2111 N ND1 . HIS A 1 254 ? 1.911 17.715 36.125 1.00 37.55 ? 254 HIS A ND1 1 ATOM 2112 C CD2 . HIS A 1 254 ? -0.166 17.585 35.459 1.00 37.79 ? 254 HIS A CD2 1 ATOM 2113 C CE1 . HIS A 1 254 ? 1.607 18.874 35.568 1.00 36.70 ? 254 HIS A CE1 1 ATOM 2114 N NE2 . HIS A 1 254 ? 0.353 18.821 35.156 1.00 37.31 ? 254 HIS A NE2 1 ATOM 2115 N N . PRO A 1 255 ? 0.172 13.604 39.769 1.00 41.43 ? 255 PRO A N 1 ATOM 2116 C CA . PRO A 1 255 ? 0.485 12.357 40.479 1.00 41.34 ? 255 PRO A CA 1 ATOM 2117 C C . PRO A 1 255 ? 0.126 11.074 39.712 1.00 41.12 ? 255 PRO A C 1 ATOM 2118 O O . PRO A 1 255 ? 0.628 10.000 40.050 1.00 41.07 ? 255 PRO A O 1 ATOM 2119 C CB . PRO A 1 255 ? -0.335 12.476 41.770 1.00 41.38 ? 255 PRO A CB 1 ATOM 2120 C CG . PRO A 1 255 ? -1.469 13.350 41.403 1.00 41.58 ? 255 PRO A CG 1 ATOM 2121 C CD . PRO A 1 255 ? -0.909 14.351 40.438 1.00 41.45 ? 255 PRO A CD 1 ATOM 2122 N N . GLU A 1 256 ? -0.723 11.190 38.692 1.00 40.69 ? 256 GLU A N 1 ATOM 2123 C CA . GLU A 1 256 ? -1.081 10.038 37.851 1.00 40.27 ? 256 GLU A CA 1 ATOM 2124 C C . GLU A 1 256 ? -0.097 9.757 36.699 1.00 39.27 ? 256 GLU A C 1 ATOM 2125 O O . GLU A 1 256 ? -0.037 8.637 36.196 1.00 39.30 ? 256 GLU A O 1 ATOM 2126 C CB . GLU A 1 256 ? -2.496 10.191 37.304 1.00 40.71 ? 256 GLU A CB 1 ATOM 2127 C CG . GLU A 1 256 ? -3.595 9.933 38.320 1.00 42.66 ? 256 GLU A CG 1 ATOM 2128 C CD . GLU A 1 256 ? -4.974 10.156 37.730 1.00 46.15 ? 256 GLU A CD 1 ATOM 2129 O OE1 . GLU A 1 256 ? -5.976 9.901 38.415 1.00 48.96 ? 256 GLU A OE1 1 ATOM 2130 O OE2 . GLU A 1 256 ? -5.072 10.593 36.573 1.00 47.89 ? 256 GLU A OE2 1 ATOM 2131 N N . PHE A 1 257 ? 0.659 10.771 36.281 1.00 37.92 ? 257 PHE A N 1 ATOM 2132 C CA . PHE A 1 257 ? 1.712 10.582 35.289 1.00 36.61 ? 257 PHE A CA 1 ATOM 2133 C C . PHE A 1 257 ? 2.825 9.678 35.841 1.00 36.10 ? 257 PHE A C 1 ATOM 2134 O O . PHE A 1 257 ? 3.322 9.907 36.944 1.00 36.12 ? 257 PHE A O 1 ATOM 2135 C CB . PHE A 1 257 ? 2.272 11.936 34.857 1.00 36.24 ? 257 PHE A CB 1 ATOM 2136 C CG . PHE A 1 257 ? 3.016 11.892 33.561 1.00 35.07 ? 257 PHE A CG 1 ATOM 2137 C CD1 . PHE A 1 257 ? 2.333 11.915 32.351 1.00 33.99 ? 257 PHE A CD1 1 ATOM 2138 C CD2 . PHE A 1 257 ? 4.402 11.825 33.547 1.00 34.31 ? 257 PHE A CD2 1 ATOM 2139 C CE1 . PHE A 1 257 ? 3.016 11.868 31.154 1.00 32.74 ? 257 PHE A CE1 1 ATOM 2140 C CE2 . PHE A 1 257 ? 5.096 11.784 32.351 1.00 33.60 ? 257 PHE A CE2 1 ATOM 2141 C CZ . PHE A 1 257 ? 4.398 11.800 31.155 1.00 32.87 ? 257 PHE A CZ 1 ATOM 2142 N N . ILE A 1 258 ? 3.194 8.654 35.070 1.00 35.50 ? 258 ILE A N 1 ATOM 2143 C CA . ILE A 1 258 ? 4.190 7.652 35.483 1.00 34.86 ? 258 ILE A CA 1 ATOM 2144 C C . ILE A 1 258 ? 5.626 8.170 35.373 1.00 34.84 ? 258 ILE A C 1 ATOM 2145 O O . ILE A 1 258 ? 6.461 7.852 36.214 1.00 35.19 ? 258 ILE A O 1 ATOM 2146 C CB . ILE A 1 258 ? 4.052 6.308 34.681 1.00 34.73 ? 258 ILE A CB 1 ATOM 2147 C CG1 . ILE A 1 258 ? 2.593 5.837 34.600 1.00 34.46 ? 258 ILE A CG1 1 ATOM 2148 C CG2 . ILE A 1 258 ? 4.946 5.207 35.254 1.00 33.72 ? 258 ILE A CG2 1 ATOM 2149 C CD1 . ILE A 1 258 ? 1.919 5.565 35.937 1.00 34.03 ? 258 ILE A CD1 1 ATOM 2150 N N . GLY A 1 259 ? 5.912 8.962 34.343 1.00 34.55 ? 259 GLY A N 1 ATOM 2151 C CA . GLY A 1 259 ? 7.262 9.486 34.130 1.00 34.17 ? 259 GLY A CA 1 ATOM 2152 C C . GLY A 1 259 ? 7.792 9.226 32.731 1.00 33.93 ? 259 GLY A C 1 ATOM 2153 O O . GLY A 1 259 ? 7.040 8.862 31.829 1.00 34.18 ? 259 GLY A O 1 ATOM 2154 N N . ILE A 1 260 ? 9.088 9.438 32.539 1.00 33.54 ? 260 ILE A N 1 ATOM 2155 C CA . ILE A 1 260 ? 9.715 9.164 31.253 1.00 33.09 ? 260 ILE A CA 1 ATOM 2156 C C . ILE A 1 260 ? 10.959 8.299 31.424 1.00 32.72 ? 260 ILE A C 1 ATOM 2157 O O . ILE A 1 260 ? 11.605 8.324 32.477 1.00 32.71 ? 260 ILE A O 1 ATOM 2158 C CB . ILE A 1 260 ? 10.097 10.461 30.482 1.00 33.35 ? 260 ILE A CB 1 ATOM 2159 C CG1 . ILE A 1 260 ? 11.270 11.176 31.153 1.00 33.71 ? 260 ILE A CG1 1 ATOM 2160 C CG2 . ILE A 1 260 ? 8.893 11.379 30.298 1.00 32.87 ? 260 ILE A CG2 1 ATOM 2161 C CD1 . ILE A 1 260 ? 11.742 12.393 30.402 1.00 35.86 ? 260 ILE A CD1 1 ATOM 2162 N N . LYS A 1 261 ? 11.271 7.523 30.389 1.00 32.01 ? 261 LYS A N 1 ATOM 2163 C CA . LYS A 1 261 ? 12.574 6.875 30.262 1.00 31.04 ? 261 LYS A CA 1 ATOM 2164 C C . LYS A 1 261 ? 13.251 7.288 28.952 1.00 30.18 ? 261 LYS A C 1 ATOM 2165 O O . LYS A 1 261 ? 12.605 7.779 28.020 1.00 29.81 ? 261 LYS A O 1 ATOM 2166 C CB . LYS A 1 261 ? 12.458 5.358 30.364 1.00 31.15 ? 261 LYS A CB 1 ATOM 2167 C CG . LYS A 1 261 ? 12.161 4.845 31.768 1.00 32.42 ? 261 LYS A CG 1 ATOM 2168 C CD . LYS A 1 261 ? 12.893 3.538 32.007 1.00 35.68 ? 261 LYS A CD 1 ATOM 2169 C CE . LYS A 1 261 ? 12.060 2.540 32.790 1.00 37.52 ? 261 LYS A CE 1 ATOM 2170 N NZ . LYS A 1 261 ? 12.129 2.737 34.258 1.00 39.95 ? 261 LYS A NZ 1 ATOM 2171 N N . ILE A 1 262 ? 14.562 7.100 28.897 1.00 29.20 ? 262 ILE A N 1 ATOM 2172 C CA . ILE A 1 262 ? 15.342 7.506 27.747 1.00 28.02 ? 262 ILE A CA 1 ATOM 2173 C C . ILE A 1 262 ? 15.952 6.291 27.055 1.00 27.54 ? 262 ILE A C 1 ATOM 2174 O O . ILE A 1 262 ? 16.556 5.435 27.706 1.00 27.51 ? 262 ILE A O 1 ATOM 2175 C CB . ILE A 1 262 ? 16.432 8.536 28.150 1.00 28.04 ? 262 ILE A CB 1 ATOM 2176 C CG1 . ILE A 1 262 ? 15.799 9.801 28.759 1.00 27.76 ? 262 ILE A CG1 1 ATOM 2177 C CG2 . ILE A 1 262 ? 17.347 8.879 26.974 1.00 27.16 ? 262 ILE A CG2 1 ATOM 2178 C CD1 . ILE A 1 262 ? 14.817 10.556 27.866 1.00 26.55 ? 262 ILE A CD1 1 ATOM 2179 N N . ILE A 1 263 ? 15.743 6.208 25.741 1.00 26.59 ? 263 ILE A N 1 ATOM 2180 C CA . ILE A 1 263 ? 16.499 5.306 24.882 1.00 25.79 ? 263 ILE A CA 1 ATOM 2181 C C . ILE A 1 263 ? 17.538 6.144 24.152 1.00 25.68 ? 263 ILE A C 1 ATOM 2182 O O . ILE A 1 263 ? 17.187 6.955 23.301 1.00 25.75 ? 263 ILE A O 1 ATOM 2183 C CB . ILE A 1 263 ? 15.598 4.585 23.851 1.00 25.68 ? 263 ILE A CB 1 ATOM 2184 C CG1 . ILE A 1 263 ? 14.561 3.707 24.562 1.00 24.33 ? 263 ILE A CG1 1 ATOM 2185 C CG2 . ILE A 1 263 ? 16.442 3.757 22.863 1.00 24.80 ? 263 ILE A CG2 1 ATOM 2186 C CD1 . ILE A 1 263 ? 13.285 3.513 23.775 1.00 23.04 ? 263 ILE A CD1 1 ATOM 2187 N N . TYR A 1 264 ? 18.806 5.957 24.503 1.00 25.59 ? 264 TYR A N 1 ATOM 2188 C CA . TYR A 1 264 ? 19.910 6.689 23.880 1.00 25.67 ? 264 TYR A CA 1 ATOM 2189 C C . TYR A 1 264 ? 20.074 6.298 22.404 1.00 25.96 ? 264 TYR A C 1 ATOM 2190 O O . TYR A 1 264 ? 19.953 5.122 22.044 1.00 25.82 ? 264 TYR A O 1 ATOM 2191 C CB . TYR A 1 264 ? 21.207 6.476 24.684 1.00 25.51 ? 264 TYR A CB 1 ATOM 2192 C CG . TYR A 1 264 ? 22.442 7.148 24.115 1.00 25.07 ? 264 TYR A CG 1 ATOM 2193 C CD1 . TYR A 1 264 ? 22.426 8.487 23.731 1.00 25.06 ? 264 TYR A CD1 1 ATOM 2194 C CD2 . TYR A 1 264 ? 23.632 6.440 23.977 1.00 25.20 ? 264 TYR A CD2 1 ATOM 2195 C CE1 . TYR A 1 264 ? 23.560 9.101 23.213 1.00 25.21 ? 264 TYR A CE1 1 ATOM 2196 C CE2 . TYR A 1 264 ? 24.779 7.040 23.460 1.00 25.27 ? 264 TYR A CE2 1 ATOM 2197 C CZ . TYR A 1 264 ? 24.732 8.370 23.077 1.00 25.61 ? 264 TYR A CZ 1 ATOM 2198 O OH . TYR A 1 264 ? 25.866 8.961 22.565 1.00 26.15 ? 264 TYR A OH 1 ATOM 2199 N N . SER A 1 265 ? 20.333 7.284 21.551 1.00 26.25 ? 265 SER A N 1 ATOM 2200 C CA . SER A 1 265 ? 20.385 7.029 20.113 1.00 27.02 ? 265 SER A CA 1 ATOM 2201 C C . SER A 1 265 ? 21.468 7.786 19.371 1.00 27.50 ? 265 SER A C 1 ATOM 2202 O O . SER A 1 265 ? 21.877 8.871 19.776 1.00 27.54 ? 265 SER A O 1 ATOM 2203 C CB . SER A 1 265 ? 19.027 7.296 19.465 1.00 26.95 ? 265 SER A CB 1 ATOM 2204 O OG . SER A 1 265 ? 18.619 8.636 19.682 1.00 27.69 ? 265 SER A OG 1 ATOM 2205 N N . ASP A 1 266 ? 21.926 7.197 18.271 1.00 28.48 ? 266 ASP A N 1 ATOM 2206 C CA . ASP A 1 266 ? 22.899 7.834 17.392 1.00 29.46 ? 266 ASP A CA 1 ATOM 2207 C C . ASP A 1 266 ? 22.544 7.550 15.928 1.00 29.86 ? 266 ASP A C 1 ATOM 2208 O O . ASP A 1 266 ? 21.814 6.609 15.639 1.00 29.90 ? 266 ASP A O 1 ATOM 2209 C CB . ASP A 1 266 ? 24.316 7.359 17.741 1.00 29.22 ? 266 ASP A CB 1 ATOM 2210 C CG . ASP A 1 266 ? 25.387 8.398 17.424 1.00 30.28 ? 266 ASP A CG 1 ATOM 2211 O OD1 . ASP A 1 266 ? 25.110 9.395 16.708 1.00 30.59 ? 266 ASP A OD1 1 ATOM 2212 O OD2 . ASP A 1 266 ? 26.526 8.214 17.902 1.00 31.74 ? 266 ASP A OD2 1 ATOM 2213 N N . HIS A 1 267 ? 23.059 8.372 15.019 1.00 30.88 ? 267 HIS A N 1 ATOM 2214 C CA . HIS A 1 267 ? 22.711 8.302 13.595 1.00 31.85 ? 267 HIS A CA 1 ATOM 2215 C C . HIS A 1 267 ? 23.386 7.146 12.866 1.00 31.69 ? 267 HIS A C 1 ATOM 2216 O O . HIS A 1 267 ? 24.585 6.902 13.026 1.00 31.74 ? 267 HIS A O 1 ATOM 2217 C CB . HIS A 1 267 ? 23.051 9.617 12.888 1.00 32.49 ? 267 HIS A CB 1 ATOM 2218 C CG . HIS A 1 267 ? 22.022 10.685 13.071 1.00 34.95 ? 267 HIS A CG 1 ATOM 2219 N ND1 . HIS A 1 267 ? 22.215 11.768 13.902 1.00 37.51 ? 267 HIS A ND1 1 ATOM 2220 C CD2 . HIS A 1 267 ? 20.787 10.836 12.533 1.00 37.24 ? 267 HIS A CD2 1 ATOM 2221 C CE1 . HIS A 1 267 ? 21.144 12.542 13.868 1.00 38.14 ? 267 HIS A CE1 1 ATOM 2222 N NE2 . HIS A 1 267 ? 20.262 11.998 13.048 1.00 38.45 ? 267 HIS A NE2 1 ATOM 2223 N N . ARG A 1 268 ? 22.606 6.458 12.040 1.00 31.57 ? 268 ARG A N 1 ATOM 2224 C CA . ARG A 1 268 ? 23.077 5.290 11.309 1.00 31.46 ? 268 ARG A CA 1 ATOM 2225 C C . ARG A 1 268 ? 23.926 5.647 10.081 1.00 31.96 ? 268 ARG A C 1 ATOM 2226 O O . ARG A 1 268 ? 24.275 4.776 9.285 1.00 31.96 ? 268 ARG A O 1 ATOM 2227 C CB . ARG A 1 268 ? 21.888 4.429 10.908 1.00 31.25 ? 268 ARG A CB 1 ATOM 2228 C CG . ARG A 1 268 ? 20.920 5.109 9.943 1.00 29.86 ? 268 ARG A CG 1 ATOM 2229 C CD . ARG A 1 268 ? 19.625 4.342 9.832 1.00 28.66 ? 268 ARG A CD 1 ATOM 2230 N NE . ARG A 1 268 ? 19.867 2.912 9.639 1.00 28.29 ? 268 ARG A NE 1 ATOM 2231 C CZ . ARG A 1 268 ? 19.483 1.965 10.485 1.00 27.06 ? 268 ARG A CZ 1 ATOM 2232 N NH1 . ARG A 1 268 ? 18.812 2.282 11.586 1.00 28.90 ? 268 ARG A NH1 1 ATOM 2233 N NH2 . ARG A 1 268 ? 19.758 0.702 10.220 1.00 25.62 ? 268 ARG A NH2 1 ATOM 2234 N N . SER A 1 269 ? 24.256 6.927 9.932 1.00 32.55 ? 269 SER A N 1 ATOM 2235 C CA . SER A 1 269 ? 25.126 7.375 8.849 1.00 33.32 ? 269 SER A CA 1 ATOM 2236 C C . SER A 1 269 ? 26.594 7.479 9.286 1.00 34.03 ? 269 SER A C 1 ATOM 2237 O O . SER A 1 269 ? 27.428 8.007 8.554 1.00 34.35 ? 269 SER A O 1 ATOM 2238 C CB . SER A 1 269 ? 24.631 8.704 8.267 1.00 33.05 ? 269 SER A CB 1 ATOM 2239 O OG . SER A 1 269 ? 24.530 9.704 9.266 1.00 33.14 ? 269 SER A OG 1 ATOM 2240 N N . LYS A 1 270 ? 26.910 6.949 10.466 1.00 34.91 ? 270 LYS A N 1 ATOM 2241 C CA . LYS A 1 270 ? 28.239 7.112 11.054 1.00 35.44 ? 270 LYS A CA 1 ATOM 2242 C C . LYS A 1 270 ? 29.101 5.854 10.979 1.00 35.84 ? 270 LYS A C 1 ATOM 2243 O O . LYS A 1 270 ? 28.596 4.744 10.804 1.00 35.78 ? 270 LYS A O 1 ATOM 2244 C CB . LYS A 1 270 ? 28.115 7.592 12.500 1.00 35.45 ? 270 LYS A CB 1 ATOM 2245 C CG . LYS A 1 270 ? 27.686 9.038 12.616 1.00 35.95 ? 270 LYS A CG 1 ATOM 2246 C CD . LYS A 1 270 ? 27.542 9.435 14.057 1.00 37.26 ? 270 LYS A CD 1 ATOM 2247 C CE . LYS A 1 270 ? 27.102 10.880 14.195 1.00 37.47 ? 270 LYS A CE 1 ATOM 2248 N NZ . LYS A 1 270 ? 26.870 11.219 15.631 1.00 37.05 ? 270 LYS A NZ 1 ATOM 2249 N N . ASP A 1 271 ? 30.408 6.049 11.113 1.00 36.52 ? 271 ASP A N 1 ATOM 2250 C CA . ASP A 1 271 ? 31.378 4.963 11.078 1.00 37.31 ? 271 ASP A CA 1 ATOM 2251 C C . ASP A 1 271 ? 31.200 4.009 12.247 1.00 37.13 ? 271 ASP A C 1 ATOM 2252 O O . ASP A 1 271 ? 30.911 4.430 13.364 1.00 37.25 ? 271 ASP A O 1 ATOM 2253 C CB . ASP A 1 271 ? 32.799 5.527 11.096 1.00 37.85 ? 271 ASP A CB 1 ATOM 2254 C CG . ASP A 1 271 ? 33.100 6.390 9.891 1.00 39.83 ? 271 ASP A CG 1 ATOM 2255 O OD1 . ASP A 1 271 ? 32.776 5.977 8.756 1.00 42.50 ? 271 ASP A OD1 1 ATOM 2256 O OD2 . ASP A 1 271 ? 33.665 7.488 10.077 1.00 42.65 ? 271 ASP A OD2 1 ATOM 2257 N N . VAL A 1 272 ? 31.398 2.721 11.984 1.00 36.97 ? 272 VAL A N 1 ATOM 2258 C CA . VAL A 1 272 ? 31.272 1.694 13.015 1.00 36.72 ? 272 VAL A CA 1 ATOM 2259 C C . VAL A 1 272 ? 32.101 2.016 14.268 1.00 36.52 ? 272 VAL A C 1 ATOM 2260 O O . VAL A 1 272 ? 31.684 1.705 15.379 1.00 36.64 ? 272 VAL A O 1 ATOM 2261 C CB . VAL A 1 272 ? 31.538 0.261 12.443 1.00 36.78 ? 272 VAL A CB 1 ATOM 2262 C CG1 . VAL A 1 272 ? 32.655 0.275 11.408 1.00 37.00 ? 272 VAL A CG1 1 ATOM 2263 C CG2 . VAL A 1 272 ? 31.807 -0.764 13.551 1.00 36.69 ? 272 VAL A CG2 1 ATOM 2264 N N . ALA A 1 273 ? 33.238 2.684 14.088 1.00 36.47 ? 273 ALA A N 1 ATOM 2265 C CA . ALA A 1 273 ? 34.088 3.114 15.212 1.00 36.31 ? 273 ALA A CA 1 ATOM 2266 C C . ALA A 1 273 ? 33.434 4.185 16.098 1.00 36.18 ? 273 ALA A C 1 ATOM 2267 O O . ALA A 1 273 ? 33.550 4.128 17.331 1.00 36.27 ? 273 ALA A O 1 ATOM 2268 C CB . ALA A 1 273 ? 35.422 3.611 14.703 1.00 36.37 ? 273 ALA A CB 1 ATOM 2269 N N . VAL A 1 274 ? 32.767 5.155 15.463 1.00 35.63 ? 274 VAL A N 1 ATOM 2270 C CA . VAL A 1 274 ? 31.976 6.183 16.155 1.00 35.12 ? 274 VAL A CA 1 ATOM 2271 C C . VAL A 1 274 ? 30.799 5.540 16.902 1.00 34.98 ? 274 VAL A C 1 ATOM 2272 O O . VAL A 1 274 ? 30.494 5.898 18.046 1.00 35.01 ? 274 VAL A O 1 ATOM 2273 C CB . VAL A 1 274 ? 31.423 7.232 15.156 1.00 35.18 ? 274 VAL A CB 1 ATOM 2274 C CG1 . VAL A 1 274 ? 30.614 8.303 15.875 1.00 35.06 ? 274 VAL A CG1 1 ATOM 2275 C CG2 . VAL A 1 274 ? 32.551 7.860 14.345 1.00 35.22 ? 274 VAL A CG2 1 ATOM 2276 N N . ILE A 1 275 ? 30.150 4.580 16.253 1.00 34.41 ? 275 ILE A N 1 ATOM 2277 C CA . ILE A 1 275 ? 29.027 3.884 16.859 1.00 33.93 ? 275 ILE A CA 1 ATOM 2278 C C . ILE A 1 275 ? 29.471 3.008 18.030 1.00 34.17 ? 275 ILE A C 1 ATOM 2279 O O . ILE A 1 275 ? 28.752 2.906 19.028 1.00 34.11 ? 275 ILE A O 1 ATOM 2280 C CB . ILE A 1 275 ? 28.204 3.116 15.801 1.00 33.53 ? 275 ILE A CB 1 ATOM 2281 C CG1 . ILE A 1 275 ? 27.582 4.107 14.797 1.00 32.22 ? 275 ILE A CG1 1 ATOM 2282 C CG2 . ILE A 1 275 ? 27.135 2.225 16.452 1.00 33.28 ? 275 ILE A CG2 1 ATOM 2283 C CD1 . ILE A 1 275 ? 26.729 5.235 15.398 1.00 29.25 ? 275 ILE A CD1 1 ATOM 2284 N N . ALA A 1 276 ? 30.660 2.412 17.912 1.00 34.43 ? 276 ALA A N 1 ATOM 2285 C CA . ALA A 1 276 ? 31.300 1.662 19.018 1.00 34.72 ? 276 ALA A CA 1 ATOM 2286 C C . ALA A 1 276 ? 31.486 2.540 20.264 1.00 34.96 ? 276 ALA A C 1 ATOM 2287 O O . ALA A 1 276 ? 31.191 2.119 21.390 1.00 34.89 ? 276 ALA A O 1 ATOM 2288 C CB . ALA A 1 276 ? 32.634 1.080 18.571 1.00 34.36 ? 276 ALA A CB 1 ATOM 2289 N N . GLU A 1 277 ? 31.957 3.763 20.041 1.00 35.40 ? 277 GLU A N 1 ATOM 2290 C CA . GLU A 1 277 ? 32.066 4.784 21.081 1.00 36.11 ? 277 GLU A CA 1 ATOM 2291 C C . GLU A 1 277 ? 30.703 5.079 21.725 1.00 35.97 ? 277 GLU A C 1 ATOM 2292 O O . GLU A 1 277 ? 30.607 5.199 22.941 1.00 35.92 ? 277 GLU A O 1 ATOM 2293 C CB . GLU A 1 277 ? 32.681 6.052 20.475 1.00 36.65 ? 277 GLU A CB 1 ATOM 2294 C CG . GLU A 1 277 ? 32.964 7.203 21.425 1.00 38.79 ? 277 GLU A CG 1 ATOM 2295 C CD . GLU A 1 277 ? 33.470 8.450 20.693 1.00 42.22 ? 277 GLU A CD 1 ATOM 2296 O OE1 . GLU A 1 277 ? 32.692 9.066 19.923 1.00 42.27 ? 277 GLU A OE1 1 ATOM 2297 O OE2 . GLU A 1 277 ? 34.649 8.820 20.903 1.00 44.53 ? 277 GLU A OE2 1 ATOM 2298 N N . SER A 1 278 ? 29.654 5.170 20.902 1.00 35.96 ? 278 SER A N 1 ATOM 2299 C CA . SER A 1 278 ? 28.293 5.437 21.380 1.00 35.59 ? 278 SER A CA 1 ATOM 2300 C C . SER A 1 278 ? 27.700 4.283 22.183 1.00 35.64 ? 278 SER A C 1 ATOM 2301 O O . SER A 1 278 ? 26.934 4.512 23.121 1.00 35.69 ? 278 SER A O 1 ATOM 2302 C CB . SER A 1 278 ? 27.365 5.790 20.217 1.00 35.59 ? 278 SER A CB 1 ATOM 2303 O OG . SER A 1 278 ? 27.834 6.934 19.529 1.00 35.11 ? 278 SER A OG 1 ATOM 2304 N N . ILE A 1 279 ? 28.048 3.051 21.810 1.00 35.60 ? 279 ILE A N 1 ATOM 2305 C CA . ILE A 1 279 ? 27.638 1.856 22.557 1.00 35.59 ? 279 ILE A CA 1 ATOM 2306 C C . ILE A 1 279 ? 28.211 1.842 23.982 1.00 35.88 ? 279 ILE A C 1 ATOM 2307 O O . ILE A 1 279 ? 27.528 1.445 24.929 1.00 36.26 ? 279 ILE A O 1 ATOM 2308 C CB . ILE A 1 279 ? 28.038 0.556 21.810 1.00 35.58 ? 279 ILE A CB 1 ATOM 2309 C CG1 . ILE A 1 279 ? 27.295 0.445 20.467 1.00 35.50 ? 279 ILE A CG1 1 ATOM 2310 C CG2 . ILE A 1 279 ? 27.806 -0.687 22.683 1.00 35.20 ? 279 ILE A CG2 1 ATOM 2311 C CD1 . ILE A 1 279 ? 25.811 0.102 20.574 1.00 34.93 ? 279 ILE A CD1 1 ATOM 2312 N N . ARG A 1 280 ? 29.457 2.281 24.130 1.00 36.10 ? 280 ARG A N 1 ATOM 2313 C CA . ARG A 1 280 ? 30.098 2.338 25.442 1.00 36.56 ? 280 ARG A CA 1 ATOM 2314 C C . ARG A 1 280 ? 29.473 3.394 26.341 1.00 36.40 ? 280 ARG A C 1 ATOM 2315 O O . ARG A 1 280 ? 29.305 3.179 27.547 1.00 36.26 ? 280 ARG A O 1 ATOM 2316 C CB . ARG A 1 280 ? 31.599 2.561 25.290 1.00 36.67 ? 280 ARG A CB 1 ATOM 2317 C CG . ARG A 1 280 ? 32.262 1.357 24.688 1.00 38.31 ? 280 ARG A CG 1 ATOM 2318 C CD . ARG A 1 280 ? 33.752 1.495 24.555 1.00 41.96 ? 280 ARG A CD 1 ATOM 2319 N NE . ARG A 1 280 ? 34.344 0.161 24.623 1.00 46.31 ? 280 ARG A NE 1 ATOM 2320 C CZ . ARG A 1 280 ? 34.549 -0.628 23.573 1.00 48.63 ? 280 ARG A CZ 1 ATOM 2321 N NH1 . ARG A 1 280 ? 34.230 -0.206 22.354 1.00 50.43 ? 280 ARG A NH1 1 ATOM 2322 N NH2 . ARG A 1 280 ? 35.081 -1.833 23.740 1.00 48.88 ? 280 ARG A NH2 1 ATOM 2323 N N . MET A 1 281 ? 29.127 4.527 25.736 1.00 36.32 ? 281 MET A N 1 ATOM 2324 C CA . MET A 1 281 ? 28.391 5.593 26.400 1.00 36.44 ? 281 MET A CA 1 ATOM 2325 C C . MET A 1 281 ? 27.070 5.055 26.960 1.00 36.36 ? 281 MET A C 1 ATOM 2326 O O . MET A 1 281 ? 26.720 5.334 28.109 1.00 36.15 ? 281 MET A O 1 ATOM 2327 C CB . MET A 1 281 ? 28.145 6.741 25.414 1.00 36.57 ? 281 MET A CB 1 ATOM 2328 C CG . MET A 1 281 ? 27.392 7.927 25.975 1.00 37.51 ? 281 MET A CG 1 ATOM 2329 S SD . MET A 1 281 ? 28.275 8.800 27.289 1.00 41.17 ? 281 MET A SD 1 ATOM 2330 C CE . MET A 1 281 ? 29.628 9.565 26.389 1.00 38.74 ? 281 MET A CE 1 ATOM 2331 N N . ALA A 1 282 ? 26.366 4.265 26.150 1.00 36.35 ? 282 ALA A N 1 ATOM 2332 C CA . ALA A 1 282 ? 25.070 3.702 26.519 1.00 36.69 ? 282 ALA A CA 1 ATOM 2333 C C . ALA A 1 282 ? 25.177 2.753 27.714 1.00 37.00 ? 282 ALA A C 1 ATOM 2334 O O . ALA A 1 282 ? 24.353 2.810 28.643 1.00 36.85 ? 282 ALA A O 1 ATOM 2335 C CB . ALA A 1 282 ? 24.433 2.999 25.323 1.00 36.59 ? 282 ALA A CB 1 ATOM 2336 N N . MET A 1 283 ? 26.198 1.899 27.688 1.00 37.30 ? 283 MET A N 1 ATOM 2337 C CA . MET A 1 283 ? 26.504 1.019 28.814 1.00 37.88 ? 283 MET A CA 1 ATOM 2338 C C . MET A 1 283 ? 26.809 1.823 30.076 1.00 37.86 ? 283 MET A C 1 ATOM 2339 O O . MET A 1 283 ? 26.288 1.522 31.155 1.00 38.00 ? 283 MET A O 1 ATOM 2340 C CB . MET A 1 283 ? 27.673 0.097 28.475 1.00 38.12 ? 283 MET A CB 1 ATOM 2341 C CG . MET A 1 283 ? 27.369 -0.889 27.343 1.00 39.75 ? 283 MET A CG 1 ATOM 2342 S SD . MET A 1 283 ? 28.612 -2.184 27.130 1.00 42.20 ? 283 MET A SD 1 ATOM 2343 C CE . MET A 1 283 ? 29.993 -1.247 26.483 1.00 42.96 ? 283 MET A CE 1 ATOM 2344 N N . GLY A 1 284 ? 27.637 2.853 29.928 1.00 37.72 ? 284 GLY A N 1 ATOM 2345 C CA . GLY A 1 284 ? 27.959 3.752 31.028 1.00 37.85 ? 284 GLY A CA 1 ATOM 2346 C C . GLY A 1 284 ? 26.734 4.439 31.605 1.00 38.02 ? 284 GLY A C 1 ATOM 2347 O O . GLY A 1 284 ? 26.595 4.557 32.825 1.00 38.16 ? 284 GLY A O 1 ATOM 2348 N N . LEU A 1 285 ? 25.845 4.891 30.721 1.00 38.03 ? 285 LEU A N 1 ATOM 2349 C CA . LEU A 1 285 ? 24.612 5.566 31.115 1.00 37.95 ? 285 LEU A CA 1 ATOM 2350 C C . LEU A 1 285 ? 23.643 4.618 31.822 1.00 38.35 ? 285 LEU A C 1 ATOM 2351 O O . LEU A 1 285 ? 22.920 5.030 32.732 1.00 38.34 ? 285 LEU A O 1 ATOM 2352 C CB . LEU A 1 285 ? 23.949 6.216 29.895 1.00 37.67 ? 285 LEU A CB 1 ATOM 2353 C CG . LEU A 1 285 ? 24.147 7.708 29.584 1.00 36.71 ? 285 LEU A CG 1 ATOM 2354 C CD1 . LEU A 1 285 ? 25.302 8.353 30.324 1.00 35.24 ? 285 LEU A CD1 1 ATOM 2355 C CD2 . LEU A 1 285 ? 24.283 7.924 28.085 1.00 35.31 ? 285 LEU A CD2 1 ATOM 2356 N N . ARG A 1 286 ? 23.633 3.355 31.400 1.00 38.83 ? 286 ARG A N 1 ATOM 2357 C CA . ARG A 1 286 ? 22.817 2.324 32.053 1.00 39.45 ? 286 ARG A CA 1 ATOM 2358 C C . ARG A 1 286 ? 23.265 2.041 33.487 1.00 39.90 ? 286 ARG A C 1 ATOM 2359 O O . ARG A 1 286 ? 22.431 1.930 34.386 1.00 39.80 ? 286 ARG A O 1 ATOM 2360 C CB . ARG A 1 286 ? 22.842 1.023 31.258 1.00 39.36 ? 286 ARG A CB 1 ATOM 2361 C CG . ARG A 1 286 ? 21.859 0.970 30.121 1.00 39.60 ? 286 ARG A CG 1 ATOM 2362 C CD . ARG A 1 286 ? 21.124 -0.355 30.154 1.00 40.20 ? 286 ARG A CD 1 ATOM 2363 N NE . ARG A 1 286 ? 19.800 -0.235 30.764 1.00 39.81 ? 286 ARG A NE 1 ATOM 2364 C CZ . ARG A 1 286 ? 19.122 -1.240 31.312 1.00 39.77 ? 286 ARG A CZ 1 ATOM 2365 N NH1 . ARG A 1 286 ? 19.639 -2.465 31.363 1.00 39.20 ? 286 ARG A NH1 1 ATOM 2366 N NH2 . ARG A 1 286 ? 17.922 -1.015 31.821 1.00 40.04 ? 286 ARG A NH2 1 ATOM 2367 N N . ILE A 1 287 ? 24.581 1.907 33.678 1.00 40.35 ? 287 ILE A N 1 ATOM 2368 C CA . ILE A 1 287 ? 25.189 1.734 34.997 1.00 40.59 ? 287 ILE A CA 1 ATOM 2369 C C . ILE A 1 287 ? 24.860 2.927 35.904 1.00 40.79 ? 287 ILE A C 1 ATOM 2370 O O . ILE A 1 287 ? 24.370 2.748 37.020 1.00 40.91 ? 287 ILE A O 1 ATOM 2371 C CB . ILE A 1 287 ? 26.739 1.555 34.892 1.00 40.80 ? 287 ILE A CB 1 ATOM 2372 C CG1 . ILE A 1 287 ? 27.114 0.264 34.137 1.00 40.73 ? 287 ILE A CG1 1 ATOM 2373 C CG2 . ILE A 1 287 ? 27.412 1.628 36.274 1.00 40.46 ? 287 ILE A CG2 1 ATOM 2374 C CD1 . ILE A 1 287 ? 26.488 -1.021 34.678 1.00 41.31 ? 287 ILE A CD1 1 ATOM 2375 N N . LYS A 1 288 ? 25.123 4.135 35.410 1.00 40.85 ? 288 LYS A N 1 ATOM 2376 C CA . LYS A 1 288 ? 24.876 5.360 36.167 1.00 40.95 ? 288 LYS A CA 1 ATOM 2377 C C . LYS A 1 288 ? 23.393 5.618 36.437 1.00 40.42 ? 288 LYS A C 1 ATOM 2378 O O . LYS A 1 288 ? 23.044 6.094 37.509 1.00 40.54 ? 288 LYS A O 1 ATOM 2379 C CB . LYS A 1 288 ? 25.501 6.564 35.456 1.00 41.38 ? 288 LYS A CB 1 ATOM 2380 C CG . LYS A 1 288 ? 26.862 6.979 35.978 1.00 43.49 ? 288 LYS A CG 1 ATOM 2381 C CD . LYS A 1 288 ? 26.731 7.829 37.244 1.00 48.08 ? 288 LYS A CD 1 ATOM 2382 C CE . LYS A 1 288 ? 28.060 8.484 37.612 1.00 50.64 ? 288 LYS A CE 1 ATOM 2383 N NZ . LYS A 1 288 ? 28.594 9.332 36.497 1.00 52.96 ? 288 LYS A NZ 1 ATOM 2384 N N . PHE A 1 289 ? 22.527 5.303 35.472 1.00 39.83 ? 289 PHE A N 1 ATOM 2385 C CA . PHE A 1 289 ? 21.098 5.609 35.589 1.00 39.19 ? 289 PHE A CA 1 ATOM 2386 C C . PHE A 1 289 ? 20.204 4.429 35.179 1.00 38.50 ? 289 PHE A C 1 ATOM 2387 O O . PHE A 1 289 ? 19.471 4.528 34.188 1.00 38.27 ? 289 PHE A O 1 ATOM 2388 C CB . PHE A 1 289 ? 20.741 6.837 34.739 1.00 39.41 ? 289 PHE A CB 1 ATOM 2389 C CG . PHE A 1 289 ? 21.583 8.046 35.019 1.00 40.02 ? 289 PHE A CG 1 ATOM 2390 C CD1 . PHE A 1 289 ? 21.252 8.914 36.057 1.00 40.83 ? 289 PHE A CD1 1 ATOM 2391 C CD2 . PHE A 1 289 ? 22.691 8.333 34.230 1.00 40.40 ? 289 PHE A CD2 1 ATOM 2392 C CE1 . PHE A 1 289 ? 22.023 10.040 36.319 1.00 41.25 ? 289 PHE A CE1 1 ATOM 2393 C CE2 . PHE A 1 289 ? 23.473 9.455 34.480 1.00 41.00 ? 289 PHE A CE2 1 ATOM 2394 C CZ . PHE A 1 289 ? 23.137 10.313 35.528 1.00 41.67 ? 289 PHE A CZ 1 ATOM 2395 N N . PRO A 1 290 ? 20.230 3.320 35.953 1.00 37.88 ? 290 PRO A N 1 ATOM 2396 C CA . PRO A 1 290 ? 19.524 2.104 35.517 1.00 37.33 ? 290 PRO A CA 1 ATOM 2397 C C . PRO A 1 290 ? 18.008 2.273 35.522 1.00 36.88 ? 290 PRO A C 1 ATOM 2398 O O . PRO A 1 290 ? 17.290 1.472 34.933 1.00 37.11 ? 290 PRO A O 1 ATOM 2399 C CB . PRO A 1 290 ? 19.951 1.064 36.553 1.00 37.01 ? 290 PRO A CB 1 ATOM 2400 C CG . PRO A 1 290 ? 20.249 1.851 37.759 1.00 37.22 ? 290 PRO A CG 1 ATOM 2401 C CD . PRO A 1 290 ? 20.822 3.151 37.294 1.00 37.63 ? 290 PRO A CD 1 ATOM 2402 N N . THR A 1 291 ? 17.548 3.332 36.170 1.00 36.41 ? 291 THR A N 1 ATOM 2403 C CA . THR A 1 291 ? 16.130 3.617 36.327 1.00 35.74 ? 291 THR A CA 1 ATOM 2404 C C . THR A 1 291 ? 15.614 4.553 35.222 1.00 35.06 ? 291 THR A C 1 ATOM 2405 O O . THR A 1 291 ? 14.408 4.617 34.973 1.00 35.14 ? 291 THR A O 1 ATOM 2406 C CB . THR A 1 291 ? 15.878 4.195 37.755 1.00 35.82 ? 291 THR A CB 1 ATOM 2407 O OG1 . THR A 1 291 ? 15.011 3.323 38.476 1.00 36.16 ? 291 THR A OG1 1 ATOM 2408 C CG2 . THR A 1 291 ? 15.331 5.640 37.753 1.00 35.70 ? 291 THR A CG2 1 ATOM 2409 N N . VAL A 1 292 ? 16.532 5.268 34.568 1.00 34.13 ? 292 VAL A N 1 ATOM 2410 C CA . VAL A 1 292 ? 16.175 6.279 33.563 1.00 33.16 ? 292 VAL A CA 1 ATOM 2411 C C . VAL A 1 292 ? 16.478 5.814 32.131 1.00 32.22 ? 292 VAL A C 1 ATOM 2412 O O . VAL A 1 292 ? 15.681 6.054 31.231 1.00 32.19 ? 292 VAL A O 1 ATOM 2413 C CB . VAL A 1 292 ? 16.857 7.656 33.843 1.00 33.26 ? 292 VAL A CB 1 ATOM 2414 C CG1 . VAL A 1 292 ? 16.276 8.756 32.950 1.00 33.54 ? 292 VAL A CG1 1 ATOM 2415 C CG2 . VAL A 1 292 ? 16.698 8.049 35.292 1.00 33.31 ? 292 VAL A CG2 1 ATOM 2416 N N . VAL A 1 293 ? 17.605 5.135 31.933 1.00 31.06 ? 293 VAL A N 1 ATOM 2417 C CA . VAL A 1 293 ? 18.078 4.798 30.585 1.00 30.23 ? 293 VAL A CA 1 ATOM 2418 C C . VAL A 1 293 ? 17.733 3.365 30.197 1.00 29.74 ? 293 VAL A C 1 ATOM 2419 O O . VAL A 1 293 ? 18.350 2.424 30.681 1.00 29.72 ? 293 VAL A O 1 ATOM 2420 C CB . VAL A 1 293 ? 19.606 5.041 30.422 1.00 30.19 ? 293 VAL A CB 1 ATOM 2421 C CG1 . VAL A 1 293 ? 20.047 4.810 28.982 1.00 29.66 ? 293 VAL A CG1 1 ATOM 2422 C CG2 . VAL A 1 293 ? 19.975 6.442 30.863 1.00 29.82 ? 293 VAL A CG2 1 ATOM 2423 N N . ALA A 1 294 ? 16.751 3.214 29.308 1.00 29.26 ? 294 ALA A N 1 ATOM 2424 C CA . ALA A 1 294 ? 16.224 1.894 28.931 1.00 28.53 ? 294 ALA A CA 1 ATOM 2425 C C . ALA A 1 294 ? 17.154 1.097 28.019 1.00 27.90 ? 294 ALA A C 1 ATOM 2426 O O . ALA A 1 294 ? 17.147 -0.129 28.043 1.00 27.87 ? 294 ALA A O 1 ATOM 2427 C CB . ALA A 1 294 ? 14.844 2.027 28.299 1.00 28.42 ? 294 ALA A CB 1 ATOM 2428 N N . GLY A 1 295 ? 17.949 1.791 27.217 1.00 27.42 ? 295 GLY A N 1 ATOM 2429 C CA . GLY A 1 295 ? 18.857 1.124 26.289 1.00 27.03 ? 295 GLY A CA 1 ATOM 2430 C C . GLY A 1 295 ? 19.315 1.994 25.134 1.00 26.72 ? 295 GLY A C 1 ATOM 2431 O O . GLY A 1 295 ? 19.496 3.207 25.300 1.00 26.76 ? 295 GLY A O 1 ATOM 2432 N N . PHE A 1 296 ? 19.483 1.368 23.963 1.00 26.27 ? 296 PHE A N 1 ATOM 2433 C CA . PHE A 1 296 ? 20.089 2.018 22.794 1.00 25.61 ? 296 PHE A CA 1 ATOM 2434 C C . PHE A 1 296 ? 19.330 1.749 21.487 1.00 25.35 ? 296 PHE A C 1 ATOM 2435 O O . PHE A 1 296 ? 18.659 0.724 21.358 1.00 25.27 ? 296 PHE A O 1 ATOM 2436 C CB . PHE A 1 296 ? 21.557 1.581 22.677 1.00 25.50 ? 296 PHE A CB 1 ATOM 2437 C CG . PHE A 1 296 ? 22.319 2.257 21.567 1.00 24.50 ? 296 PHE A CG 1 ATOM 2438 C CD1 . PHE A 1 296 ? 22.524 1.608 20.358 1.00 24.05 ? 296 PHE A CD1 1 ATOM 2439 C CD2 . PHE A 1 296 ? 22.850 3.533 21.742 1.00 24.83 ? 296 PHE A CD2 1 ATOM 2440 C CE1 . PHE A 1 296 ? 23.238 2.223 19.329 1.00 24.75 ? 296 PHE A CE1 1 ATOM 2441 C CE2 . PHE A 1 296 ? 23.564 4.164 20.720 1.00 24.92 ? 296 PHE A CE2 1 ATOM 2442 C CZ . PHE A 1 296 ? 23.759 3.505 19.508 1.00 24.82 ? 296 PHE A CZ 1 ATOM 2443 N N . ASP A 1 297 ? 19.456 2.674 20.530 1.00 25.17 ? 297 ASP A N 1 ATOM 2444 C CA . ASP A 1 297 ? 18.821 2.589 19.199 1.00 25.00 ? 297 ASP A CA 1 ATOM 2445 C C . ASP A 1 297 ? 19.659 3.331 18.149 1.00 24.88 ? 297 ASP A C 1 ATOM 2446 O O . ASP A 1 297 ? 20.403 4.260 18.474 1.00 24.50 ? 297 ASP A O 1 ATOM 2447 C CB . ASP A 1 297 ? 17.411 3.200 19.253 1.00 25.18 ? 297 ASP A CB 1 ATOM 2448 C CG . ASP A 1 297 ? 16.627 3.065 17.939 1.00 26.06 ? 297 ASP A CG 1 ATOM 2449 O OD1 . ASP A 1 297 ? 17.050 2.339 17.004 1.00 27.72 ? 297 ASP A OD1 1 ATOM 2450 O OD2 . ASP A 1 297 ? 15.544 3.686 17.856 1.00 26.18 ? 297 ASP A OD2 1 ATOM 2451 N N . LEU A 1 298 ? 19.536 2.903 16.893 1.00 24.75 ? 298 LEU A N 1 ATOM 2452 C CA . LEU A 1 298 ? 20.129 3.609 15.756 1.00 24.43 ? 298 LEU A CA 1 ATOM 2453 C C . LEU A 1 298 ? 19.032 4.255 14.901 1.00 24.36 ? 298 LEU A C 1 ATOM 2454 O O . LEU A 1 298 ? 18.057 3.594 14.518 1.00 24.30 ? 298 LEU A O 1 ATOM 2455 C CB . LEU A 1 298 ? 20.985 2.653 14.916 1.00 24.50 ? 298 LEU A CB 1 ATOM 2456 C CG . LEU A 1 298 ? 22.286 2.161 15.554 1.00 24.06 ? 298 LEU A CG 1 ATOM 2457 C CD1 . LEU A 1 298 ? 22.754 0.869 14.917 1.00 24.22 ? 298 LEU A CD1 1 ATOM 2458 C CD2 . LEU A 1 298 ? 23.359 3.228 15.440 1.00 24.66 ? 298 LEU A CD2 1 ATOM 2459 N N . VAL A 1 299 ? 19.196 5.542 14.602 1.00 23.97 ? 299 VAL A N 1 ATOM 2460 C CA . VAL A 1 299 ? 18.154 6.315 13.929 1.00 23.65 ? 299 VAL A CA 1 ATOM 2461 C C . VAL A 1 299 ? 18.655 6.956 12.636 1.00 23.90 ? 299 VAL A C 1 ATOM 2462 O O . VAL A 1 299 ? 19.822 6.836 12.291 1.00 23.90 ? 299 VAL A O 1 ATOM 2463 C CB . VAL A 1 299 ? 17.550 7.414 14.863 1.00 23.65 ? 299 VAL A CB 1 ATOM 2464 C CG1 . VAL A 1 299 ? 16.886 6.785 16.073 1.00 23.08 ? 299 VAL A CG1 1 ATOM 2465 C CG2 . VAL A 1 299 ? 18.613 8.456 15.283 1.00 22.88 ? 299 VAL A CG2 1 ATOM 2466 N N . GLY A 1 300 ? 17.764 7.656 11.937 1.00 24.26 ? 300 GLY A N 1 ATOM 2467 C CA . GLY A 1 300 ? 18.096 8.281 10.658 1.00 24.62 ? 300 GLY A CA 1 ATOM 2468 C C . GLY A 1 300 ? 17.504 7.529 9.479 1.00 24.86 ? 300 GLY A C 1 ATOM 2469 O O . GLY A 1 300 ? 16.841 6.510 9.662 1.00 24.66 ? 300 GLY A O 1 ATOM 2470 N N . HIS A 1 301 ? 17.751 8.042 8.272 1.00 25.22 ? 301 HIS A N 1 ATOM 2471 C CA . HIS A 1 301 ? 17.217 7.473 7.030 1.00 25.66 ? 301 HIS A CA 1 ATOM 2472 C C . HIS A 1 301 ? 17.791 6.073 6.825 1.00 26.06 ? 301 HIS A C 1 ATOM 2473 O O . HIS A 1 301 ? 18.994 5.919 6.591 1.00 26.44 ? 301 HIS A O 1 ATOM 2474 C CB . HIS A 1 301 ? 17.553 8.409 5.860 1.00 25.61 ? 301 HIS A CB 1 ATOM 2475 C CG . HIS A 1 301 ? 16.768 8.158 4.605 1.00 26.09 ? 301 HIS A CG 1 ATOM 2476 N ND1 . HIS A 1 301 ? 15.697 7.291 4.540 1.00 26.70 ? 301 HIS A ND1 1 ATOM 2477 C CD2 . HIS A 1 301 ? 16.885 8.699 3.370 1.00 26.16 ? 301 HIS A CD2 1 ATOM 2478 C CE1 . HIS A 1 301 ? 15.205 7.291 3.315 1.00 25.74 ? 301 HIS A CE1 1 ATOM 2479 N NE2 . HIS A 1 301 ? 15.905 8.141 2.586 1.00 26.00 ? 301 HIS A NE2 1 ATOM 2480 N N . GLU A 1 302 ? 16.930 5.061 6.941 1.00 26.25 ? 302 GLU A N 1 ATOM 2481 C CA . GLU A 1 302 ? 17.359 3.667 6.944 1.00 26.74 ? 302 GLU A CA 1 ATOM 2482 C C . GLU A 1 302 ? 17.823 3.198 5.560 1.00 27.12 ? 302 GLU A C 1 ATOM 2483 O O . GLU A 1 302 ? 18.777 2.425 5.443 1.00 26.89 ? 302 GLU A O 1 ATOM 2484 C CB . GLU A 1 302 ? 16.244 2.761 7.487 1.00 26.75 ? 302 GLU A CB 1 ATOM 2485 C CG . GLU A 1 302 ? 16.719 1.373 7.954 1.00 27.24 ? 302 GLU A CG 1 ATOM 2486 C CD . GLU A 1 302 ? 15.600 0.476 8.503 1.00 27.61 ? 302 GLU A CD 1 ATOM 2487 O OE1 . GLU A 1 302 ? 14.508 0.991 8.828 1.00 27.88 ? 302 GLU A OE1 1 ATOM 2488 O OE2 . GLU A 1 302 ? 15.819 -0.753 8.613 1.00 26.97 ? 302 GLU A OE2 1 ATOM 2489 N N . ASP A 1 303 ? 17.151 3.676 4.519 1.00 27.73 ? 303 ASP A N 1 ATOM 2490 C CA . ASP A 1 303 ? 17.470 3.290 3.145 1.00 28.54 ? 303 ASP A CA 1 ATOM 2491 C C . ASP A 1 303 ? 18.893 3.670 2.729 1.00 28.75 ? 303 ASP A C 1 ATOM 2492 O O . ASP A 1 303 ? 19.562 2.915 2.010 1.00 28.73 ? 303 ASP A O 1 ATOM 2493 C CB . ASP A 1 303 ? 16.471 3.905 2.163 1.00 28.55 ? 303 ASP A CB 1 ATOM 2494 C CG . ASP A 1 303 ? 15.181 3.104 2.047 1.00 29.84 ? 303 ASP A CG 1 ATOM 2495 O OD1 . ASP A 1 303 ? 15.018 2.077 2.759 1.00 30.38 ? 303 ASP A OD1 1 ATOM 2496 O OD2 . ASP A 1 303 ? 14.320 3.511 1.231 1.00 30.91 ? 303 ASP A OD2 1 ATOM 2497 N N . THR A 1 304 ? 19.347 4.829 3.200 1.00 28.95 ? 304 THR A N 1 ATOM 2498 C CA . THR A 1 304 ? 20.610 5.418 2.752 1.00 29.25 ? 304 THR A CA 1 ATOM 2499 C C . THR A 1 304 ? 21.791 5.237 3.721 1.00 29.67 ? 304 THR A C 1 ATOM 2500 O O . THR A 1 304 ? 22.931 5.470 3.338 1.00 29.88 ? 304 THR A O 1 ATOM 2501 C CB . THR A 1 304 ? 20.445 6.931 2.442 1.00 28.95 ? 304 THR A CB 1 ATOM 2502 O OG1 . THR A 1 304 ? 19.817 7.578 3.551 1.00 28.67 ? 304 THR A OG1 1 ATOM 2503 C CG2 . THR A 1 304 ? 19.597 7.139 1.216 1.00 28.15 ? 304 THR A CG2 1 ATOM 2504 N N . GLY A 1 305 ? 21.523 4.851 4.965 1.00 29.99 ? 305 GLY A N 1 ATOM 2505 C CA . GLY A 1 305 ? 22.583 4.686 5.961 1.00 30.67 ? 305 GLY A CA 1 ATOM 2506 C C . GLY A 1 305 ? 23.128 3.269 6.028 1.00 31.15 ? 305 GLY A C 1 ATOM 2507 O O . GLY A 1 305 ? 22.822 2.445 5.166 1.00 31.34 ? 305 GLY A O 1 ATOM 2508 N N . HIS A 1 306 ? 23.934 2.980 7.050 1.00 31.47 ? 306 HIS A N 1 ATOM 2509 C CA . HIS A 1 306 ? 24.462 1.628 7.250 1.00 32.27 ? 306 HIS A CA 1 ATOM 2510 C C . HIS A 1 306 ? 23.373 0.686 7.748 1.00 32.20 ? 306 HIS A C 1 ATOM 2511 O O . HIS A 1 306 ? 22.411 1.123 8.373 1.00 32.44 ? 306 HIS A O 1 ATOM 2512 C CB . HIS A 1 306 ? 25.628 1.639 8.248 1.00 32.62 ? 306 HIS A CB 1 ATOM 2513 C CG . HIS A 1 306 ? 26.916 2.150 7.677 1.00 34.76 ? 306 HIS A CG 1 ATOM 2514 N ND1 . HIS A 1 306 ? 27.315 3.464 7.793 1.00 36.42 ? 306 HIS A ND1 1 ATOM 2515 C CD2 . HIS A 1 306 ? 27.895 1.519 6.984 1.00 36.81 ? 306 HIS A CD2 1 ATOM 2516 C CE1 . HIS A 1 306 ? 28.481 3.623 7.194 1.00 37.80 ? 306 HIS A CE1 1 ATOM 2517 N NE2 . HIS A 1 306 ? 28.858 2.456 6.699 1.00 38.20 ? 306 HIS A NE2 1 ATOM 2518 N N . SER A 1 307 ? 23.529 -0.603 7.476 1.00 32.26 ? 307 SER A N 1 ATOM 2519 C CA . SER A 1 307 ? 22.635 -1.616 8.018 1.00 32.46 ? 307 SER A CA 1 ATOM 2520 C C . SER A 1 307 ? 23.103 -2.086 9.396 1.00 32.83 ? 307 SER A C 1 ATOM 2521 O O . SER A 1 307 ? 24.243 -1.830 9.798 1.00 32.96 ? 307 SER A O 1 ATOM 2522 C CB . SER A 1 307 ? 22.569 -2.809 7.080 1.00 32.19 ? 307 SER A CB 1 ATOM 2523 O OG . SER A 1 307 ? 23.756 -3.571 7.192 1.00 32.84 ? 307 SER A OG 1 ATOM 2524 N N . LEU A 1 308 ? 22.224 -2.788 10.111 1.00 33.10 ? 308 LEU A N 1 ATOM 2525 C CA . LEU A 1 308 ? 22.575 -3.361 11.407 1.00 33.02 ? 308 LEU A CA 1 ATOM 2526 C C . LEU A 1 308 ? 23.731 -4.342 11.293 1.00 33.54 ? 308 LEU A C 1 ATOM 2527 O O . LEU A 1 308 ? 24.583 -4.393 12.173 1.00 33.59 ? 308 LEU A O 1 ATOM 2528 C CB . LEU A 1 308 ? 21.362 -4.033 12.058 1.00 32.56 ? 308 LEU A CB 1 ATOM 2529 C CG . LEU A 1 308 ? 20.197 -3.130 12.463 1.00 31.57 ? 308 LEU A CG 1 ATOM 2530 C CD1 . LEU A 1 308 ? 19.155 -3.935 13.206 1.00 29.92 ? 308 LEU A CD1 1 ATOM 2531 C CD2 . LEU A 1 308 ? 20.672 -1.951 13.307 1.00 30.75 ? 308 LEU A CD2 1 ATOM 2532 N N . HIS A 1 309 ? 23.747 -5.112 10.206 1.00 34.31 ? 309 HIS A N 1 ATOM 2533 C CA . HIS A 1 309 ? 24.842 -6.036 9.911 1.00 35.21 ? 309 HIS A CA 1 ATOM 2534 C C . HIS A 1 309 ? 26.163 -5.291 9.834 1.00 35.12 ? 309 HIS A C 1 ATOM 2535 O O . HIS A 1 309 ? 27.135 -5.693 10.467 1.00 35.09 ? 309 HIS A O 1 ATOM 2536 C CB . HIS A 1 309 ? 24.591 -6.778 8.603 1.00 35.64 ? 309 HIS A CB 1 ATOM 2537 C CG . HIS A 1 309 ? 25.518 -7.930 8.380 1.00 38.00 ? 309 HIS A CG 1 ATOM 2538 N ND1 . HIS A 1 309 ? 25.361 -9.146 9.016 1.00 40.37 ? 309 HIS A ND1 1 ATOM 2539 C CD2 . HIS A 1 309 ? 26.607 -8.057 7.587 1.00 39.44 ? 309 HIS A CD2 1 ATOM 2540 C CE1 . HIS A 1 309 ? 26.315 -9.971 8.626 1.00 40.39 ? 309 HIS A CE1 1 ATOM 2541 N NE2 . HIS A 1 309 ? 27.085 -9.334 7.761 1.00 41.01 ? 309 HIS A NE2 1 ATOM 2542 N N . ASP A 1 310 ? 26.177 -4.196 9.073 1.00 35.29 ? 310 ASP A N 1 ATOM 2543 C CA . ASP A 1 310 ? 27.347 -3.322 8.949 1.00 35.61 ? 310 ASP A CA 1 ATOM 2544 C C . ASP A 1 310 ? 27.945 -2.980 10.303 1.00 35.59 ? 310 ASP A C 1 ATOM 2545 O O . ASP A 1 310 ? 29.163 -2.867 10.437 1.00 35.47 ? 310 ASP A O 1 ATOM 2546 C CB . ASP A 1 310 ? 26.981 -2.021 8.222 1.00 35.85 ? 310 ASP A CB 1 ATOM 2547 C CG . ASP A 1 310 ? 26.671 -2.231 6.743 1.00 36.87 ? 310 ASP A CG 1 ATOM 2548 O OD1 . ASP A 1 310 ? 27.109 -3.255 6.168 1.00 38.66 ? 310 ASP A OD1 1 ATOM 2549 O OD2 . ASP A 1 310 ? 26.002 -1.358 6.149 1.00 37.92 ? 310 ASP A OD2 1 ATOM 2550 N N . TYR A 1 311 ? 27.078 -2.834 11.303 1.00 35.70 ? 311 TYR A N 1 ATOM 2551 C CA . TYR A 1 311 ? 27.488 -2.463 12.656 1.00 35.79 ? 311 TYR A CA 1 ATOM 2552 C C . TYR A 1 311 ? 27.744 -3.634 13.606 1.00 36.59 ? 311 TYR A C 1 ATOM 2553 O O . TYR A 1 311 ? 27.989 -3.400 14.793 1.00 36.58 ? 311 TYR A O 1 ATOM 2554 C CB . TYR A 1 311 ? 26.442 -1.538 13.294 1.00 35.39 ? 311 TYR A CB 1 ATOM 2555 C CG . TYR A 1 311 ? 26.416 -0.119 12.764 1.00 33.83 ? 311 TYR A CG 1 ATOM 2556 C CD1 . TYR A 1 311 ? 27.563 0.677 12.771 1.00 32.13 ? 311 TYR A CD1 1 ATOM 2557 C CD2 . TYR A 1 311 ? 25.238 0.435 12.283 1.00 32.53 ? 311 TYR A CD2 1 ATOM 2558 C CE1 . TYR A 1 311 ? 27.538 1.972 12.292 1.00 31.07 ? 311 TYR A CE1 1 ATOM 2559 C CE2 . TYR A 1 311 ? 25.201 1.740 11.814 1.00 31.76 ? 311 TYR A CE2 1 ATOM 2560 C CZ . TYR A 1 311 ? 26.352 2.500 11.819 1.00 30.89 ? 311 TYR A CZ 1 ATOM 2561 O OH . TYR A 1 311 ? 26.308 3.795 11.346 1.00 30.56 ? 311 TYR A OH 1 ATOM 2562 N N . LYS A 1 312 ? 27.697 -4.875 13.104 1.00 37.63 ? 312 LYS A N 1 ATOM 2563 C CA . LYS A 1 312 ? 27.808 -6.067 13.973 1.00 39.02 ? 312 LYS A CA 1 ATOM 2564 C C . LYS A 1 312 ? 28.910 -5.949 15.027 1.00 39.33 ? 312 LYS A C 1 ATOM 2565 O O . LYS A 1 312 ? 28.662 -6.150 16.220 1.00 39.26 ? 312 LYS A O 1 ATOM 2566 C CB . LYS A 1 312 ? 28.002 -7.362 13.168 1.00 39.26 ? 312 LYS A CB 1 ATOM 2567 C CG . LYS A 1 312 ? 27.968 -8.639 14.047 1.00 41.74 ? 312 LYS A CG 1 ATOM 2568 C CD . LYS A 1 312 ? 28.128 -9.944 13.241 1.00 45.30 ? 312 LYS A CD 1 ATOM 2569 C CE . LYS A 1 312 ? 29.570 -10.160 12.777 1.00 47.22 ? 312 LYS A CE 1 ATOM 2570 N NZ . LYS A 1 312 ? 29.663 -11.196 11.699 1.00 49.75 ? 312 LYS A NZ 1 ATOM 2571 N N . GLU A 1 313 ? 30.120 -5.616 14.580 1.00 39.89 ? 313 GLU A N 1 ATOM 2572 C CA . GLU A 1 313 ? 31.266 -5.500 15.479 1.00 40.46 ? 313 GLU A CA 1 ATOM 2573 C C . GLU A 1 313 ? 30.939 -4.634 16.694 1.00 39.87 ? 313 GLU A C 1 ATOM 2574 O O . GLU A 1 313 ? 31.127 -5.069 17.835 1.00 40.06 ? 313 GLU A O 1 ATOM 2575 C CB . GLU A 1 313 ? 32.504 -4.982 14.733 1.00 41.03 ? 313 GLU A CB 1 ATOM 2576 C CG . GLU A 1 313 ? 33.118 -6.015 13.787 1.00 44.13 ? 313 GLU A CG 1 ATOM 2577 C CD . GLU A 1 313 ? 33.347 -7.361 14.466 1.00 48.57 ? 313 GLU A CD 1 ATOM 2578 O OE1 . GLU A 1 313 ? 34.383 -7.523 15.150 1.00 50.71 ? 313 GLU A OE1 1 ATOM 2579 O OE2 . GLU A 1 313 ? 32.487 -8.257 14.320 1.00 49.91 ? 313 GLU A OE2 1 ATOM 2580 N N . ALA A 1 314 ? 30.415 -3.434 16.438 1.00 38.93 ? 314 ALA A N 1 ATOM 2581 C CA . ALA A 1 314 ? 30.056 -2.483 17.492 1.00 37.99 ? 314 ALA A CA 1 ATOM 2582 C C . ALA A 1 314 ? 28.857 -2.922 18.345 1.00 37.54 ? 314 ALA A C 1 ATOM 2583 O O . ALA A 1 314 ? 28.857 -2.726 19.571 1.00 37.20 ? 314 ALA A O 1 ATOM 2584 C CB . ALA A 1 314 ? 29.807 -1.112 16.893 1.00 37.99 ? 314 ALA A CB 1 ATOM 2585 N N . LEU A 1 315 ? 27.851 -3.522 17.707 1.00 36.95 ? 315 LEU A N 1 ATOM 2586 C CA . LEU A 1 315 ? 26.633 -3.941 18.412 1.00 36.72 ? 315 LEU A CA 1 ATOM 2587 C C . LEU A 1 315 ? 26.824 -5.186 19.278 1.00 37.45 ? 315 LEU A C 1 ATOM 2588 O O . LEU A 1 315 ? 25.969 -5.501 20.117 1.00 37.23 ? 315 LEU A O 1 ATOM 2589 C CB . LEU A 1 315 ? 25.462 -4.131 17.434 1.00 36.08 ? 315 LEU A CB 1 ATOM 2590 C CG . LEU A 1 315 ? 25.012 -2.891 16.650 1.00 33.85 ? 315 LEU A CG 1 ATOM 2591 C CD1 . LEU A 1 315 ? 23.852 -3.206 15.735 1.00 31.54 ? 315 LEU A CD1 1 ATOM 2592 C CD2 . LEU A 1 315 ? 24.651 -1.740 17.570 1.00 30.07 ? 315 LEU A CD2 1 ATOM 2593 N N . MET A 1 316 ? 27.946 -5.877 19.075 1.00 38.32 ? 316 MET A N 1 ATOM 2594 C CA . MET A 1 316 ? 28.281 -7.080 19.840 1.00 39.47 ? 316 MET A CA 1 ATOM 2595 C C . MET A 1 316 ? 29.163 -6.796 21.063 1.00 39.92 ? 316 MET A C 1 ATOM 2596 O O . MET A 1 316 ? 29.384 -7.680 21.897 1.00 39.95 ? 316 MET A O 1 ATOM 2597 C CB . MET A 1 316 ? 28.934 -8.140 18.935 1.00 39.58 ? 316 MET A CB 1 ATOM 2598 C CG . MET A 1 316 ? 27.975 -8.841 17.975 1.00 40.58 ? 316 MET A CG 1 ATOM 2599 S SD . MET A 1 316 ? 26.499 -9.528 18.770 1.00 44.18 ? 316 MET A SD 1 ATOM 2600 C CE . MET A 1 316 ? 27.195 -10.879 19.728 1.00 43.75 ? 316 MET A CE 1 ATOM 2601 N N . ILE A 1 317 ? 29.653 -5.562 21.166 1.00 40.74 ? 317 ILE A N 1 ATOM 2602 C CA . ILE A 1 317 ? 30.486 -5.126 22.299 1.00 41.59 ? 317 ILE A CA 1 ATOM 2603 C C . ILE A 1 317 ? 29.908 -5.472 23.687 1.00 42.81 ? 317 ILE A C 1 ATOM 2604 O O . ILE A 1 317 ? 30.625 -6.035 24.516 1.00 43.17 ? 317 ILE A O 1 ATOM 2605 C CB . ILE A 1 317 ? 30.858 -3.611 22.200 1.00 41.36 ? 317 ILE A CB 1 ATOM 2606 C CG1 . ILE A 1 317 ? 31.912 -3.396 21.113 1.00 40.20 ? 317 ILE A CG1 1 ATOM 2607 C CG2 . ILE A 1 317 ? 31.360 -3.069 23.540 1.00 41.18 ? 317 ILE A CG2 1 ATOM 2608 C CD1 . ILE A 1 317 ? 32.150 -1.948 20.752 1.00 39.00 ? 317 ILE A CD1 1 ATOM 2609 N N . PRO A 1 318 ? 28.619 -5.156 23.948 1.00 43.95 ? 318 PRO A N 1 ATOM 2610 C CA . PRO A 1 318 ? 28.085 -5.536 25.261 1.00 44.77 ? 318 PRO A CA 1 ATOM 2611 C C . PRO A 1 318 ? 28.191 -7.034 25.534 1.00 45.75 ? 318 PRO A C 1 ATOM 2612 O O . PRO A 1 318 ? 28.639 -7.426 26.611 1.00 45.98 ? 318 PRO A O 1 ATOM 2613 C CB . PRO A 1 318 ? 26.616 -5.111 25.180 1.00 44.78 ? 318 PRO A CB 1 ATOM 2614 C CG . PRO A 1 318 ? 26.601 -4.010 24.179 1.00 44.26 ? 318 PRO A CG 1 ATOM 2615 C CD . PRO A 1 318 ? 27.632 -4.385 23.165 1.00 43.87 ? 318 PRO A CD 1 ATOM 2616 N N . ALA A 1 319 ? 27.791 -7.855 24.564 1.00 46.91 ? 319 ALA A N 1 ATOM 2617 C CA . ALA A 1 319 ? 27.820 -9.317 24.707 1.00 48.00 ? 319 ALA A CA 1 ATOM 2618 C C . ALA A 1 319 ? 29.228 -9.851 25.017 1.00 48.80 ? 319 ALA A C 1 ATOM 2619 O O . ALA A 1 319 ? 29.399 -10.707 25.892 1.00 48.86 ? 319 ALA A O 1 ATOM 2620 C CB . ALA A 1 319 ? 27.249 -9.986 23.464 1.00 47.77 ? 319 ALA A CB 1 ATOM 2621 N N . LYS A 1 320 ? 30.225 -9.322 24.310 1.00 49.61 ? 320 LYS A N 1 ATOM 2622 C CA . LYS A 1 320 ? 31.626 -9.668 24.544 1.00 50.37 ? 320 LYS A CA 1 ATOM 2623 C C . LYS A 1 320 ? 32.125 -9.234 25.928 1.00 50.65 ? 320 LYS A C 1 ATOM 2624 O O . LYS A 1 320 ? 33.068 -9.826 26.452 1.00 51.06 ? 320 LYS A O 1 ATOM 2625 C CB . LYS A 1 320 ? 32.520 -9.061 23.456 1.00 50.58 ? 320 LYS A CB 1 ATOM 2626 C CG . LYS A 1 320 ? 32.440 -9.752 22.095 1.00 51.28 ? 320 LYS A CG 1 ATOM 2627 C CD . LYS A 1 320 ? 33.322 -9.058 21.045 1.00 52.84 ? 320 LYS A CD 1 ATOM 2628 C CE . LYS A 1 320 ? 32.675 -7.773 20.512 1.00 53.79 ? 320 LYS A CE 1 ATOM 2629 N NZ . LYS A 1 320 ? 33.460 -7.118 19.425 1.00 53.92 ? 320 LYS A NZ 1 ATOM 2630 N N . ASP A 1 321 ? 31.508 -8.201 26.508 1.00 50.72 ? 321 ASP A N 1 ATOM 2631 C CA . ASP A 1 321 ? 31.835 -7.755 27.865 1.00 50.59 ? 321 ASP A CA 1 ATOM 2632 C C . ASP A 1 321 ? 30.946 -8.438 28.899 1.00 50.08 ? 321 ASP A C 1 ATOM 2633 O O . ASP A 1 321 ? 31.023 -8.132 30.094 1.00 50.28 ? 321 ASP A O 1 ATOM 2634 C CB . ASP A 1 321 ? 31.686 -6.237 27.996 1.00 51.10 ? 321 ASP A CB 1 ATOM 2635 C CG . ASP A 1 321 ? 32.688 -5.463 27.150 1.00 52.95 ? 321 ASP A CG 1 ATOM 2636 O OD1 . ASP A 1 321 ? 33.484 -6.089 26.409 1.00 55.35 ? 321 ASP A OD1 1 ATOM 2637 O OD2 . ASP A 1 321 ? 32.673 -4.213 27.226 1.00 54.53 ? 321 ASP A OD2 1 ATOM 2638 N N . GLY A 1 322 ? 30.096 -9.354 28.437 1.00 49.31 ? 322 GLY A N 1 ATOM 2639 C CA . GLY A 1 322 ? 29.140 -10.049 29.305 1.00 48.18 ? 322 GLY A CA 1 ATOM 2640 C C . GLY A 1 322 ? 28.101 -9.125 29.920 1.00 47.36 ? 322 GLY A C 1 ATOM 2641 O O . GLY A 1 322 ? 27.636 -9.359 31.034 1.00 47.39 ? 322 GLY A O 1 ATOM 2642 N N . VAL A 1 323 ? 27.744 -8.071 29.189 1.00 46.33 ? 323 VAL A N 1 ATOM 2643 C CA . VAL A 1 323 ? 26.762 -7.096 29.649 1.00 45.11 ? 323 VAL A CA 1 ATOM 2644 C C . VAL A 1 323 ? 25.566 -7.088 28.700 1.00 43.97 ? 323 VAL A C 1 ATOM 2645 O O . VAL A 1 323 ? 25.725 -7.265 27.490 1.00 44.16 ? 323 VAL A O 1 ATOM 2646 C CB . VAL A 1 323 ? 27.388 -5.678 29.759 1.00 45.41 ? 323 VAL A CB 1 ATOM 2647 C CG1 . VAL A 1 323 ? 26.336 -4.631 30.120 1.00 45.63 ? 323 VAL A CG1 1 ATOM 2648 C CG2 . VAL A 1 323 ? 28.513 -5.664 30.796 1.00 45.36 ? 323 VAL A CG2 1 ATOM 2649 N N . LYS A 1 324 ? 24.372 -6.904 29.255 1.00 42.28 ? 324 LYS A N 1 ATOM 2650 C CA . LYS A 1 324 ? 23.156 -6.776 28.450 1.00 40.54 ? 324 LYS A CA 1 ATOM 2651 C C . LYS A 1 324 ? 22.748 -5.317 28.269 1.00 38.97 ? 324 LYS A C 1 ATOM 2652 O O . LYS A 1 324 ? 22.261 -4.676 29.200 1.00 38.68 ? 324 LYS A O 1 ATOM 2653 C CB . LYS A 1 324 ? 21.999 -7.577 29.062 1.00 40.78 ? 324 LYS A CB 1 ATOM 2654 N N . LEU A 1 325 ? 22.974 -4.801 27.064 1.00 37.16 ? 325 LEU A N 1 ATOM 2655 C CA . LEU A 1 325 ? 22.474 -3.492 26.658 1.00 35.08 ? 325 LEU A CA 1 ATOM 2656 C C . LEU A 1 325 ? 21.202 -3.719 25.844 1.00 33.74 ? 325 LEU A C 1 ATOM 2657 O O . LEU A 1 325 ? 21.272 -4.157 24.694 1.00 33.74 ? 325 LEU A O 1 ATOM 2658 C CB . LEU A 1 325 ? 23.522 -2.721 25.833 1.00 34.86 ? 325 LEU A CB 1 ATOM 2659 C CG . LEU A 1 325 ? 23.147 -1.362 25.204 1.00 34.40 ? 325 LEU A CG 1 ATOM 2660 C CD1 . LEU A 1 325 ? 22.825 -0.299 26.249 1.00 32.77 ? 325 LEU A CD1 1 ATOM 2661 C CD2 . LEU A 1 325 ? 24.245 -0.865 24.271 1.00 33.81 ? 325 LEU A CD2 1 ATOM 2662 N N . PRO A 1 326 ? 20.031 -3.435 26.439 1.00 32.18 ? 326 PRO A N 1 ATOM 2663 C CA . PRO A 1 326 ? 18.812 -3.633 25.672 1.00 31.12 ? 326 PRO A CA 1 ATOM 2664 C C . PRO A 1 326 ? 18.792 -2.753 24.421 1.00 30.08 ? 326 PRO A C 1 ATOM 2665 O O . PRO A 1 326 ? 19.330 -1.642 24.415 1.00 29.88 ? 326 PRO A O 1 ATOM 2666 C CB . PRO A 1 326 ? 17.704 -3.220 26.653 1.00 31.09 ? 326 PRO A CB 1 ATOM 2667 C CG . PRO A 1 326 ? 18.337 -3.296 28.005 1.00 31.06 ? 326 PRO A CG 1 ATOM 2668 C CD . PRO A 1 326 ? 19.750 -2.893 27.779 1.00 31.96 ? 326 PRO A CD 1 ATOM 2669 N N . TYR A 1 327 ? 18.180 -3.269 23.366 1.00 28.78 ? 327 TYR A N 1 ATOM 2670 C CA . TYR A 1 327 ? 18.103 -2.557 22.103 1.00 27.56 ? 327 TYR A CA 1 ATOM 2671 C C . TYR A 1 327 ? 16.663 -2.344 21.688 1.00 26.43 ? 327 TYR A C 1 ATOM 2672 O O . TYR A 1 327 ? 15.794 -3.142 22.023 1.00 26.03 ? 327 TYR A O 1 ATOM 2673 C CB . TYR A 1 327 ? 18.835 -3.338 21.014 1.00 27.63 ? 327 TYR A CB 1 ATOM 2674 C CG . TYR A 1 327 ? 20.341 -3.323 21.110 1.00 27.00 ? 327 TYR A CG 1 ATOM 2675 C CD1 . TYR A 1 327 ? 21.043 -2.125 21.202 1.00 26.84 ? 327 TYR A CD1 1 ATOM 2676 C CD2 . TYR A 1 327 ? 21.071 -4.516 21.053 1.00 27.10 ? 327 TYR A CD2 1 ATOM 2677 C CE1 . TYR A 1 327 ? 22.433 -2.114 21.261 1.00 27.92 ? 327 TYR A CE1 1 ATOM 2678 C CE2 . TYR A 1 327 ? 22.458 -4.518 21.115 1.00 26.55 ? 327 TYR A CE2 1 ATOM 2679 C CZ . TYR A 1 327 ? 23.133 -3.314 21.217 1.00 27.72 ? 327 TYR A CZ 1 ATOM 2680 O OH . TYR A 1 327 ? 24.508 -3.294 21.275 1.00 28.62 ? 327 TYR A OH 1 ATOM 2681 N N . PHE A 1 328 ? 16.433 -1.262 20.951 1.00 25.61 ? 328 PHE A N 1 ATOM 2682 C CA . PHE A 1 328 ? 15.092 -0.851 20.511 1.00 24.55 ? 328 PHE A CA 1 ATOM 2683 C C . PHE A 1 328 ? 15.170 -0.373 19.066 1.00 24.11 ? 328 PHE A C 1 ATOM 2684 O O . PHE A 1 328 ? 14.776 0.755 18.752 1.00 24.74 ? 328 PHE A O 1 ATOM 2685 C CB . PHE A 1 328 ? 14.552 0.270 21.419 1.00 24.44 ? 328 PHE A CB 1 ATOM 2686 C CG . PHE A 1 328 ? 14.410 -0.134 22.859 1.00 23.85 ? 328 PHE A CG 1 ATOM 2687 C CD1 . PHE A 1 328 ? 13.197 -0.627 23.342 1.00 23.15 ? 328 PHE A CD1 1 ATOM 2688 C CD2 . PHE A 1 328 ? 15.498 -0.046 23.732 1.00 23.08 ? 328 PHE A CD2 1 ATOM 2689 C CE1 . PHE A 1 328 ? 13.067 -1.015 24.677 1.00 23.16 ? 328 PHE A CE1 1 ATOM 2690 C CE2 . PHE A 1 328 ? 15.382 -0.446 25.063 1.00 22.55 ? 328 PHE A CE2 1 ATOM 2691 C CZ . PHE A 1 328 ? 14.165 -0.930 25.538 1.00 22.75 ? 328 PHE A CZ 1 ATOM 2692 N N . PHE A 1 329 ? 15.675 -1.235 18.185 1.00 23.18 ? 329 PHE A N 1 ATOM 2693 C CA . PHE A 1 329 ? 16.027 -0.844 16.821 1.00 22.29 ? 329 PHE A CA 1 ATOM 2694 C C . PHE A 1 329 ? 14.860 -0.408 15.927 1.00 21.88 ? 329 PHE A C 1 ATOM 2695 O O . PHE A 1 329 ? 13.868 -1.121 15.798 1.00 21.65 ? 329 PHE A O 1 ATOM 2696 C CB . PHE A 1 329 ? 16.792 -1.975 16.115 1.00 21.96 ? 329 PHE A CB 1 ATOM 2697 C CG . PHE A 1 329 ? 18.158 -2.250 16.684 1.00 21.32 ? 329 PHE A CG 1 ATOM 2698 C CD1 . PHE A 1 329 ? 19.141 -1.263 16.710 1.00 20.34 ? 329 PHE A CD1 1 ATOM 2699 C CD2 . PHE A 1 329 ? 18.480 -3.519 17.161 1.00 20.81 ? 329 PHE A CD2 1 ATOM 2700 C CE1 . PHE A 1 329 ? 20.413 -1.534 17.229 1.00 19.65 ? 329 PHE A CE1 1 ATOM 2701 C CE2 . PHE A 1 329 ? 19.747 -3.795 17.677 1.00 19.71 ? 329 PHE A CE2 1 ATOM 2702 C CZ . PHE A 1 329 ? 20.711 -2.804 17.711 1.00 19.32 ? 329 PHE A CZ 1 ATOM 2703 N N . HIS A 1 330 ? 14.997 0.765 15.313 1.00 21.63 ? 330 HIS A N 1 ATOM 2704 C CA . HIS A 1 330 ? 14.283 1.073 14.077 1.00 21.69 ? 330 HIS A CA 1 ATOM 2705 C C . HIS A 1 330 ? 14.673 0.004 13.059 1.00 21.87 ? 330 HIS A C 1 ATOM 2706 O O . HIS A 1 330 ? 15.864 -0.286 12.888 1.00 22.10 ? 330 HIS A O 1 ATOM 2707 C CB . HIS A 1 330 ? 14.752 2.414 13.524 1.00 21.54 ? 330 HIS A CB 1 ATOM 2708 C CG . HIS A 1 330 ? 14.130 3.610 14.174 1.00 22.09 ? 330 HIS A CG 1 ATOM 2709 N ND1 . HIS A 1 330 ? 14.262 3.888 15.518 1.00 23.07 ? 330 HIS A ND1 1 ATOM 2710 C CD2 . HIS A 1 330 ? 13.411 4.629 13.649 1.00 21.20 ? 330 HIS A CD2 1 ATOM 2711 C CE1 . HIS A 1 330 ? 13.640 5.018 15.796 1.00 22.18 ? 330 HIS A CE1 1 ATOM 2712 N NE2 . HIS A 1 330 ? 13.120 5.490 14.679 1.00 22.01 ? 330 HIS A NE2 1 ATOM 2713 N N . ALA A 1 331 ? 13.701 -0.591 12.378 1.00 21.85 ? 331 ALA A N 1 ATOM 2714 C CA . ALA A 1 331 ? 14.018 -1.665 11.433 1.00 22.03 ? 331 ALA A CA 1 ATOM 2715 C C . ALA A 1 331 ? 12.938 -1.875 10.384 1.00 22.02 ? 331 ALA A C 1 ATOM 2716 O O . ALA A 1 331 ? 11.752 -1.957 10.710 1.00 21.94 ? 331 ALA A O 1 ATOM 2717 C CB . ALA A 1 331 ? 14.308 -2.989 12.183 1.00 21.98 ? 331 ALA A CB 1 ATOM 2718 N N . GLY A 1 332 ? 13.373 -1.977 9.129 1.00 22.20 ? 332 GLY A N 1 ATOM 2719 C CA . GLY A 1 332 ? 12.492 -2.263 7.993 1.00 22.29 ? 332 GLY A CA 1 ATOM 2720 C C . GLY A 1 332 ? 11.544 -1.126 7.675 1.00 22.54 ? 332 GLY A C 1 ATOM 2721 O O . GLY A 1 332 ? 10.430 -1.348 7.202 1.00 22.83 ? 332 GLY A O 1 ATOM 2722 N N . GLU A 1 333 ? 11.978 0.095 7.962 1.00 22.55 ? 333 GLU A N 1 ATOM 2723 C CA . GLU A 1 333 ? 11.220 1.276 7.604 1.00 23.09 ? 333 GLU A CA 1 ATOM 2724 C C . GLU A 1 333 ? 11.481 1.591 6.124 1.00 22.71 ? 333 GLU A C 1 ATOM 2725 O O . GLU A 1 333 ? 12.112 2.594 5.788 1.00 22.74 ? 333 GLU A O 1 ATOM 2726 C CB . GLU A 1 333 ? 11.623 2.447 8.503 1.00 23.43 ? 333 GLU A CB 1 ATOM 2727 C CG . GLU A 1 333 ? 10.693 3.633 8.425 1.00 26.06 ? 333 GLU A CG 1 ATOM 2728 C CD . GLU A 1 333 ? 11.281 4.882 9.042 1.00 30.72 ? 333 GLU A CD 1 ATOM 2729 O OE1 . GLU A 1 333 ? 12.471 4.858 9.438 1.00 31.37 ? 333 GLU A OE1 1 ATOM 2730 O OE2 . GLU A 1 333 ? 10.545 5.896 9.131 1.00 32.58 ? 333 GLU A OE2 1 ATOM 2731 N N . THR A 1 334 ? 10.992 0.716 5.247 1.00 22.33 ? 334 THR A N 1 ATOM 2732 C CA . THR A 1 334 ? 11.334 0.765 3.833 1.00 21.68 ? 334 THR A CA 1 ATOM 2733 C C . THR A 1 334 ? 10.244 0.176 2.942 1.00 21.61 ? 334 THR A C 1 ATOM 2734 O O . THR A 1 334 ? 9.459 -0.665 3.377 1.00 21.38 ? 334 THR A O 1 ATOM 2735 C CB . THR A 1 334 ? 12.680 0.030 3.558 1.00 21.86 ? 334 THR A CB 1 ATOM 2736 O OG1 . THR A 1 334 ? 13.012 0.124 2.164 1.00 21.26 ? 334 THR A OG1 1 ATOM 2737 C CG2 . THR A 1 334 ? 12.606 -1.455 3.978 1.00 20.91 ? 334 THR A CG2 1 ATOM 2738 N N . ASP A 1 335 ? 10.210 0.628 1.691 1.00 21.69 ? 335 ASP A N 1 ATOM 2739 C CA . ASP A 1 335 ? 9.373 0.013 0.657 1.00 21.93 ? 335 ASP A CA 1 ATOM 2740 C C . ASP A 1 335 ? 10.104 -1.126 -0.069 1.00 22.12 ? 335 ASP A C 1 ATOM 2741 O O . ASP A 1 335 ? 9.473 -1.886 -0.811 1.00 22.24 ? 335 ASP A O 1 ATOM 2742 C CB . ASP A 1 335 ? 8.945 1.053 -0.371 1.00 21.69 ? 335 ASP A CB 1 ATOM 2743 C CG . ASP A 1 335 ? 7.967 2.056 0.179 1.00 21.78 ? 335 ASP A CG 1 ATOM 2744 O OD1 . ASP A 1 335 ? 7.051 1.647 0.909 1.00 24.01 ? 335 ASP A OD1 1 ATOM 2745 O OD2 . ASP A 1 335 ? 8.091 3.253 -0.140 1.00 20.81 ? 335 ASP A OD2 1 ATOM 2746 N N . TRP A 1 336 ? 11.426 -1.227 0.115 1.00 22.28 ? 336 TRP A N 1 ATOM 2747 C CA . TRP A 1 336 ? 12.205 -2.305 -0.523 1.00 22.52 ? 336 TRP A CA 1 ATOM 2748 C C . TRP A 1 336 ? 11.934 -3.643 0.144 1.00 22.68 ? 336 TRP A C 1 ATOM 2749 O O . TRP A 1 336 ? 11.597 -3.714 1.329 1.00 22.65 ? 336 TRP A O 1 ATOM 2750 C CB . TRP A 1 336 ? 13.711 -1.996 -0.572 1.00 22.44 ? 336 TRP A CB 1 ATOM 2751 C CG . TRP A 1 336 ? 14.007 -0.670 -1.251 1.00 23.02 ? 336 TRP A CG 1 ATOM 2752 C CD1 . TRP A 1 336 ? 14.418 0.482 -0.644 1.00 23.14 ? 336 TRP A CD1 1 ATOM 2753 C CD2 . TRP A 1 336 ? 13.864 -0.355 -2.647 1.00 22.91 ? 336 TRP A CD2 1 ATOM 2754 N NE1 . TRP A 1 336 ? 14.551 1.487 -1.569 1.00 23.12 ? 336 TRP A NE1 1 ATOM 2755 C CE2 . TRP A 1 336 ? 14.217 1.004 -2.807 1.00 23.70 ? 336 TRP A CE2 1 ATOM 2756 C CE3 . TRP A 1 336 ? 13.479 -1.090 -3.776 1.00 23.47 ? 336 TRP A CE3 1 ATOM 2757 C CZ2 . TRP A 1 336 ? 14.195 1.650 -4.057 1.00 23.79 ? 336 TRP A CZ2 1 ATOM 2758 C CZ3 . TRP A 1 336 ? 13.452 -0.449 -5.017 1.00 23.52 ? 336 TRP A CZ3 1 ATOM 2759 C CH2 . TRP A 1 336 ? 13.809 0.909 -5.146 1.00 23.97 ? 336 TRP A CH2 1 ATOM 2760 N N . GLN A 1 337 ? 12.037 -4.696 -0.651 1.00 23.11 ? 337 GLN A N 1 ATOM 2761 C CA . GLN A 1 337 ? 11.753 -6.046 -0.211 1.00 23.47 ? 337 GLN A CA 1 ATOM 2762 C C . GLN A 1 337 ? 12.865 -6.946 -0.735 1.00 24.09 ? 337 GLN A C 1 ATOM 2763 O O . GLN A 1 337 ? 13.228 -6.871 -1.917 1.00 23.95 ? 337 GLN A O 1 ATOM 2764 C CB . GLN A 1 337 ? 10.383 -6.508 -0.732 1.00 23.18 ? 337 GLN A CB 1 ATOM 2765 C CG . GLN A 1 337 ? 10.048 -7.956 -0.372 1.00 22.80 ? 337 GLN A CG 1 ATOM 2766 C CD . GLN A 1 337 ? 8.831 -8.517 -1.101 1.00 23.11 ? 337 GLN A CD 1 ATOM 2767 O OE1 . GLN A 1 337 ? 8.493 -9.692 -0.929 1.00 24.36 ? 337 GLN A OE1 1 ATOM 2768 N NE2 . GLN A 1 337 ? 8.164 -7.687 -1.909 1.00 21.23 ? 337 GLN A NE2 1 ATOM 2769 N N . GLY A 1 338 ? 13.402 -7.778 0.155 1.00 24.79 ? 338 GLY A N 1 ATOM 2770 C CA . GLY A 1 338 ? 14.484 -8.694 -0.185 1.00 25.94 ? 338 GLY A CA 1 ATOM 2771 C C . GLY A 1 338 ? 15.845 -8.023 -0.314 1.00 26.68 ? 338 GLY A C 1 ATOM 2772 O O . GLY A 1 338 ? 16.776 -8.611 -0.865 1.00 27.13 ? 338 GLY A O 1 ATOM 2773 N N . THR A 1 339 ? 15.969 -6.798 0.195 1.00 27.08 ? 339 THR A N 1 ATOM 2774 C CA . THR A 1 339 ? 17.246 -6.092 0.162 1.00 27.48 ? 339 THR A CA 1 ATOM 2775 C C . THR A 1 339 ? 17.920 -6.127 1.536 1.00 27.79 ? 339 THR A C 1 ATOM 2776 O O . THR A 1 339 ? 17.365 -6.678 2.484 1.00 28.18 ? 339 THR A O 1 ATOM 2777 C CB . THR A 1 339 ? 17.103 -4.628 -0.338 1.00 27.37 ? 339 THR A CB 1 ATOM 2778 O OG1 . THR A 1 339 ? 16.401 -3.843 0.629 1.00 27.41 ? 339 THR A OG1 1 ATOM 2779 C CG2 . THR A 1 339 ? 16.367 -4.573 -1.647 1.00 27.36 ? 339 THR A CG2 1 ATOM 2780 N N . SER A 1 340 ? 19.111 -5.540 1.633 1.00 27.94 ? 340 SER A N 1 ATOM 2781 C CA . SER A 1 340 ? 19.858 -5.453 2.891 1.00 28.19 ? 340 SER A CA 1 ATOM 2782 C C . SER A 1 340 ? 19.156 -4.584 3.947 1.00 28.23 ? 340 SER A C 1 ATOM 2783 O O . SER A 1 340 ? 19.476 -4.660 5.141 1.00 28.42 ? 340 SER A O 1 ATOM 2784 C CB . SER A 1 340 ? 21.235 -4.870 2.619 1.00 28.07 ? 340 SER A CB 1 ATOM 2785 O OG . SER A 1 340 ? 21.096 -3.548 2.133 1.00 28.84 ? 340 SER A OG 1 ATOM 2786 N N . ILE A 1 341 ? 18.212 -3.757 3.501 1.00 27.98 ? 341 ILE A N 1 ATOM 2787 C CA . ILE A 1 341 ? 17.522 -2.819 4.390 1.00 27.83 ? 341 ILE A CA 1 ATOM 2788 C C . ILE A 1 341 ? 16.401 -3.491 5.186 1.00 27.90 ? 341 ILE A C 1 ATOM 2789 O O . ILE A 1 341 ? 16.333 -3.335 6.408 1.00 27.72 ? 341 ILE A O 1 ATOM 2790 C CB . ILE A 1 341 ? 16.979 -1.592 3.620 1.00 27.74 ? 341 ILE A CB 1 ATOM 2791 C CG1 . ILE A 1 341 ? 18.083 -0.987 2.749 1.00 27.80 ? 341 ILE A CG1 1 ATOM 2792 C CG2 . ILE A 1 341 ? 16.448 -0.556 4.585 1.00 26.67 ? 341 ILE A CG2 1 ATOM 2793 C CD1 . ILE A 1 341 ? 17.576 -0.145 1.587 1.00 27.27 ? 341 ILE A CD1 1 ATOM 2794 N N . ASP A 1 342 ? 15.533 -4.240 4.503 1.00 27.89 ? 342 ASP A N 1 ATOM 2795 C CA . ASP A 1 342 ? 14.434 -4.924 5.191 1.00 27.92 ? 342 ASP A CA 1 ATOM 2796 C C . ASP A 1 342 ? 14.862 -6.147 6.018 1.00 27.69 ? 342 ASP A C 1 ATOM 2797 O O . ASP A 1 342 ? 14.124 -6.578 6.908 1.00 27.35 ? 342 ASP A O 1 ATOM 2798 C CB . ASP A 1 342 ? 13.242 -5.221 4.261 1.00 27.94 ? 342 ASP A CB 1 ATOM 2799 C CG . ASP A 1 342 ? 13.643 -5.900 2.971 1.00 28.70 ? 342 ASP A CG 1 ATOM 2800 O OD1 . ASP A 1 342 ? 14.277 -5.361 2.102 1.00 28.50 ? 342 ASP A OD1 1 ATOM 2801 O OD2 . ASP A 1 342 ? 13.302 -7.020 2.742 1.00 30.08 ? 342 ASP A OD2 1 ATOM 2802 N N . ARG A 1 343 ? 16.056 -6.679 5.740 1.00 27.61 ? 343 ARG A N 1 ATOM 2803 C CA . ARG A 1 343 ? 16.645 -7.741 6.573 1.00 27.50 ? 343 ARG A CA 1 ATOM 2804 C C . ARG A 1 343 ? 17.101 -7.219 7.940 1.00 26.87 ? 343 ARG A C 1 ATOM 2805 O O . ARG A 1 343 ? 17.395 -8.006 8.836 1.00 26.74 ? 343 ARG A O 1 ATOM 2806 C CB . ARG A 1 343 ? 17.788 -8.470 5.855 1.00 27.68 ? 343 ARG A CB 1 ATOM 2807 C CG . ARG A 1 343 ? 17.295 -9.447 4.796 1.00 29.98 ? 343 ARG A CG 1 ATOM 2808 C CD . ARG A 1 343 ? 18.366 -10.426 4.330 1.00 32.20 ? 343 ARG A CD 1 ATOM 2809 N NE . ARG A 1 343 ? 19.481 -9.763 3.663 1.00 34.34 ? 343 ARG A NE 1 ATOM 2810 C CZ . ARG A 1 343 ? 19.464 -9.349 2.399 1.00 34.49 ? 343 ARG A CZ 1 ATOM 2811 N NH1 . ARG A 1 343 ? 18.376 -9.513 1.652 1.00 35.23 ? 343 ARG A NH1 1 ATOM 2812 N NH2 . ARG A 1 343 ? 20.534 -8.759 1.885 1.00 34.64 ? 343 ARG A NH2 1 ATOM 2813 N N . ASN A 1 344 ? 17.137 -5.894 8.097 1.00 26.37 ? 344 ASN A N 1 ATOM 2814 C CA . ASN A 1 344 ? 17.392 -5.262 9.403 1.00 25.99 ? 344 ASN A CA 1 ATOM 2815 C C . ASN A 1 344 ? 16.424 -5.717 10.495 1.00 26.21 ? 344 ASN A C 1 ATOM 2816 O O . ASN A 1 344 ? 16.782 -5.720 11.673 1.00 26.20 ? 344 ASN A O 1 ATOM 2817 C CB . ASN A 1 344 ? 17.382 -3.730 9.305 1.00 25.40 ? 344 ASN A CB 1 ATOM 2818 C CG . ASN A 1 344 ? 18.659 -3.167 8.677 1.00 24.94 ? 344 ASN A CG 1 ATOM 2819 O OD1 . ASN A 1 344 ? 19.741 -3.751 8.815 1.00 22.67 ? 344 ASN A OD1 1 ATOM 2820 N ND2 . ASN A 1 344 ? 18.538 -2.016 7.990 1.00 22.37 ? 344 ASN A ND2 1 ATOM 2821 N N . ILE A 1 345 ? 15.206 -6.095 10.109 1.00 26.47 ? 345 ILE A N 1 ATOM 2822 C CA . ILE A 1 345 ? 14.251 -6.668 11.059 1.00 27.09 ? 345 ILE A CA 1 ATOM 2823 C C . ILE A 1 345 ? 14.788 -8.005 11.587 1.00 27.43 ? 345 ILE A C 1 ATOM 2824 O O . ILE A 1 345 ? 14.797 -8.239 12.789 1.00 27.89 ? 345 ILE A O 1 ATOM 2825 C CB . ILE A 1 345 ? 12.824 -6.858 10.455 1.00 26.89 ? 345 ILE A CB 1 ATOM 2826 C CG1 . ILE A 1 345 ? 12.318 -5.555 9.812 1.00 27.03 ? 345 ILE A CG1 1 ATOM 2827 C CG2 . ILE A 1 345 ? 11.853 -7.348 11.533 1.00 26.54 ? 345 ILE A CG2 1 ATOM 2828 C CD1 . ILE A 1 345 ? 10.971 -5.674 9.081 1.00 25.41 ? 345 ILE A CD1 1 ATOM 2829 N N . LEU A 1 346 ? 15.240 -8.864 10.682 1.00 27.82 ? 346 LEU A N 1 ATOM 2830 C CA . LEU A 1 346 ? 15.842 -10.132 11.050 1.00 28.34 ? 346 LEU A CA 1 ATOM 2831 C C . LEU A 1 346 ? 17.025 -9.928 12.006 1.00 28.75 ? 346 LEU A C 1 ATOM 2832 O O . LEU A 1 346 ? 17.125 -10.605 13.044 1.00 28.53 ? 346 LEU A O 1 ATOM 2833 C CB . LEU A 1 346 ? 16.286 -10.894 9.792 1.00 28.22 ? 346 LEU A CB 1 ATOM 2834 C CG . LEU A 1 346 ? 17.114 -12.175 9.970 1.00 28.45 ? 346 LEU A CG 1 ATOM 2835 C CD1 . LEU A 1 346 ? 16.346 -13.235 10.737 1.00 27.91 ? 346 LEU A CD1 1 ATOM 2836 C CD2 . LEU A 1 346 ? 17.543 -12.716 8.623 1.00 28.89 ? 346 LEU A CD2 1 ATOM 2837 N N . ASP A 1 347 ? 17.898 -8.985 11.658 1.00 29.09 ? 347 ASP A N 1 ATOM 2838 C CA . ASP A 1 347 ? 19.108 -8.720 12.432 1.00 29.98 ? 347 ASP A CA 1 ATOM 2839 C C . ASP A 1 347 ? 18.833 -8.019 13.764 1.00 30.13 ? 347 ASP A C 1 ATOM 2840 O O . ASP A 1 347 ? 19.592 -8.175 14.714 1.00 30.41 ? 347 ASP A O 1 ATOM 2841 C CB . ASP A 1 347 ? 20.141 -7.948 11.594 1.00 30.08 ? 347 ASP A CB 1 ATOM 2842 C CG . ASP A 1 347 ? 20.857 -8.841 10.579 1.00 31.14 ? 347 ASP A CG 1 ATOM 2843 O OD1 . ASP A 1 347 ? 21.180 -10.006 10.917 1.00 31.16 ? 347 ASP A OD1 1 ATOM 2844 O OD2 . ASP A 1 347 ? 21.104 -8.375 9.444 1.00 32.43 ? 347 ASP A OD2 1 ATOM 2845 N N . ALA A 1 348 ? 17.745 -7.260 13.831 1.00 30.35 ? 348 ALA A N 1 ATOM 2846 C CA . ALA A 1 348 ? 17.294 -6.674 15.090 1.00 30.47 ? 348 ALA A CA 1 ATOM 2847 C C . ALA A 1 348 ? 16.879 -7.785 16.045 1.00 30.58 ? 348 ALA A C 1 ATOM 2848 O O . ALA A 1 348 ? 17.230 -7.765 17.228 1.00 30.54 ? 348 ALA A O 1 ATOM 2849 C CB . ALA A 1 348 ? 16.132 -5.720 14.852 1.00 30.33 ? 348 ALA A CB 1 ATOM 2850 N N . LEU A 1 349 ? 16.128 -8.748 15.519 1.00 30.87 ? 349 LEU A N 1 ATOM 2851 C CA . LEU A 1 349 ? 15.717 -9.923 16.286 1.00 31.14 ? 349 LEU A CA 1 ATOM 2852 C C . LEU A 1 349 ? 16.918 -10.768 16.735 1.00 31.41 ? 349 LEU A C 1 ATOM 2853 O O . LEU A 1 349 ? 16.971 -11.196 17.884 1.00 31.37 ? 349 LEU A O 1 ATOM 2854 C CB . LEU A 1 349 ? 14.716 -10.754 15.478 1.00 30.92 ? 349 LEU A CB 1 ATOM 2855 C CG . LEU A 1 349 ? 13.211 -10.658 15.795 1.00 30.81 ? 349 LEU A CG 1 ATOM 2856 C CD1 . LEU A 1 349 ? 12.830 -9.607 16.860 1.00 28.95 ? 349 LEU A CD1 1 ATOM 2857 C CD2 . LEU A 1 349 ? 12.417 -10.452 14.510 1.00 29.89 ? 349 LEU A CD2 1 ATOM 2858 N N . MET A 1 350 ? 17.889 -10.970 15.840 1.00 31.73 ? 350 MET A N 1 ATOM 2859 C CA . MET A 1 350 ? 19.092 -11.736 16.171 1.00 32.24 ? 350 MET A CA 1 ATOM 2860 C C . MET A 1 350 ? 19.910 -11.065 17.273 1.00 32.35 ? 350 MET A C 1 ATOM 2861 O O . MET A 1 350 ? 20.641 -11.736 18.009 1.00 32.49 ? 350 MET A O 1 ATOM 2862 C CB . MET A 1 350 ? 19.965 -12.001 14.933 1.00 32.26 ? 350 MET A CB 1 ATOM 2863 C CG . MET A 1 350 ? 19.335 -12.867 13.835 1.00 32.85 ? 350 MET A CG 1 ATOM 2864 S SD . MET A 1 350 ? 18.647 -14.451 14.357 1.00 35.47 ? 350 MET A SD 1 ATOM 2865 C CE . MET A 1 350 ? 16.941 -14.025 14.738 1.00 34.51 ? 350 MET A CE 1 ATOM 2866 N N . LEU A 1 351 ? 19.773 -9.746 17.388 1.00 32.41 ? 351 LEU A N 1 ATOM 2867 C CA . LEU A 1 351 ? 20.430 -8.987 18.456 1.00 32.51 ? 351 LEU A CA 1 ATOM 2868 C C . LEU A 1 351 ? 19.565 -8.814 19.714 1.00 32.77 ? 351 LEU A C 1 ATOM 2869 O O . LEU A 1 351 ? 19.881 -7.995 20.574 1.00 32.76 ? 351 LEU A O 1 ATOM 2870 C CB . LEU A 1 351 ? 20.898 -7.625 17.942 1.00 32.19 ? 351 LEU A CB 1 ATOM 2871 C CG . LEU A 1 351 ? 21.956 -7.613 16.838 1.00 31.88 ? 351 LEU A CG 1 ATOM 2872 C CD1 . LEU A 1 351 ? 21.954 -6.259 16.165 1.00 30.56 ? 351 LEU A CD1 1 ATOM 2873 C CD2 . LEU A 1 351 ? 23.353 -7.954 17.354 1.00 31.09 ? 351 LEU A CD2 1 ATOM 2874 N N . ASN A 1 352 ? 18.491 -9.595 19.823 1.00 33.26 ? 352 ASN A N 1 ATOM 2875 C CA . ASN A 1 352 ? 17.618 -9.596 21.012 1.00 33.91 ? 352 ASN A CA 1 ATOM 2876 C C . ASN A 1 352 ? 16.946 -8.248 21.307 1.00 32.88 ? 352 ASN A C 1 ATOM 2877 O O . ASN A 1 352 ? 16.860 -7.828 22.459 1.00 32.71 ? 352 ASN A O 1 ATOM 2878 C CB . ASN A 1 352 ? 18.367 -10.091 22.272 1.00 34.86 ? 352 ASN A CB 1 ATOM 2879 C CG . ASN A 1 352 ? 19.107 -11.400 22.046 1.00 38.86 ? 352 ASN A CG 1 ATOM 2880 O OD1 . ASN A 1 352 ? 18.554 -12.364 21.501 1.00 41.33 ? 352 ASN A OD1 1 ATOM 2881 N ND2 . ASN A 1 352 ? 20.370 -11.441 22.472 1.00 44.67 ? 352 ASN A ND2 1 ATOM 2882 N N . THR A 1 353 ? 16.472 -7.574 20.264 1.00 31.65 ? 353 THR A N 1 ATOM 2883 C CA . THR A 1 353 ? 15.809 -6.296 20.443 1.00 30.34 ? 353 THR A CA 1 ATOM 2884 C C . THR A 1 353 ? 14.542 -6.483 21.299 1.00 29.65 ? 353 THR A C 1 ATOM 2885 O O . THR A 1 353 ? 13.849 -7.501 21.182 1.00 29.65 ? 353 THR A O 1 ATOM 2886 C CB . THR A 1 353 ? 15.523 -5.604 19.080 1.00 30.26 ? 353 THR A CB 1 ATOM 2887 O OG1 . THR A 1 353 ? 15.273 -4.209 19.286 1.00 30.07 ? 353 THR A OG1 1 ATOM 2888 C CG2 . THR A 1 353 ? 14.337 -6.244 18.358 1.00 30.18 ? 353 THR A CG2 1 ATOM 2889 N N . THR A 1 354 ? 14.284 -5.522 22.189 1.00 28.46 ? 354 THR A N 1 ATOM 2890 C CA . THR A 1 354 ? 13.115 -5.552 23.067 1.00 27.09 ? 354 THR A CA 1 ATOM 2891 C C . THR A 1 354 ? 11.871 -5.162 22.281 1.00 26.55 ? 354 THR A C 1 ATOM 2892 O O . THR A 1 354 ? 10.819 -5.772 22.441 1.00 26.30 ? 354 THR A O 1 ATOM 2893 C CB . THR A 1 354 ? 13.286 -4.598 24.259 1.00 27.16 ? 354 THR A CB 1 ATOM 2894 O OG1 . THR A 1 354 ? 14.445 -4.967 25.005 1.00 26.95 ? 354 THR A OG1 1 ATOM 2895 C CG2 . THR A 1 354 ? 12.064 -4.618 25.184 1.00 26.65 ? 354 THR A CG2 1 ATOM 2896 N N . ARG A 1 355 ? 12.011 -4.135 21.442 1.00 25.82 ? 355 ARG A N 1 ATOM 2897 C CA . ARG A 1 355 ? 10.970 -3.696 20.516 1.00 24.95 ? 355 ARG A CA 1 ATOM 2898 C C . ARG A 1 355 ? 11.564 -3.402 19.125 1.00 24.57 ? 355 ARG A C 1 ATOM 2899 O O . ARG A 1 355 ? 12.759 -3.138 19.002 1.00 24.44 ? 355 ARG A O 1 ATOM 2900 C CB . ARG A 1 355 ? 10.286 -2.445 21.058 1.00 24.80 ? 355 ARG A CB 1 ATOM 2901 C CG . ARG A 1 355 ? 9.282 -2.689 22.150 1.00 24.04 ? 355 ARG A CG 1 ATOM 2902 C CD . ARG A 1 355 ? 8.504 -1.416 22.443 1.00 23.06 ? 355 ARG A CD 1 ATOM 2903 N NE . ARG A 1 355 ? 8.955 -0.882 23.712 1.00 24.21 ? 355 ARG A NE 1 ATOM 2904 C CZ . ARG A 1 355 ? 9.512 0.291 23.930 1.00 23.70 ? 355 ARG A CZ 1 ATOM 2905 N NH1 . ARG A 1 355 ? 9.663 1.107 23.007 1.00 24.44 ? 355 ARG A NH1 1 ATOM 2906 N NH2 . ARG A 1 355 ? 9.904 0.682 25.091 1.00 23.43 ? 355 ARG A NH2 1 ATOM 2907 N N . ILE A 1 356 ? 10.722 -3.470 18.093 1.00 23.77 ? 356 ILE A N 1 ATOM 2908 C CA . ILE A 1 356 ? 11.083 -3.106 16.727 1.00 23.09 ? 356 ILE A CA 1 ATOM 2909 C C . ILE A 1 356 ? 10.399 -1.781 16.342 1.00 23.15 ? 356 ILE A C 1 ATOM 2910 O O . ILE A 1 356 ? 9.166 -1.676 16.364 1.00 23.40 ? 356 ILE A O 1 ATOM 2911 C CB . ILE A 1 356 ? 10.649 -4.219 15.718 1.00 23.03 ? 356 ILE A CB 1 ATOM 2912 C CG1 . ILE A 1 356 ? 11.359 -5.553 16.027 1.00 23.09 ? 356 ILE A CG1 1 ATOM 2913 C CG2 . ILE A 1 356 ? 10.896 -3.783 14.277 1.00 22.00 ? 356 ILE A CG2 1 ATOM 2914 C CD1 . ILE A 1 356 ? 10.689 -6.803 15.410 1.00 20.71 ? 356 ILE A CD1 1 ATOM 2915 N N . GLY A 1 357 ? 11.186 -0.775 15.983 1.00 22.55 ? 357 GLY A N 1 ATOM 2916 C CA . GLY A 1 357 ? 10.627 0.487 15.504 1.00 21.91 ? 357 GLY A CA 1 ATOM 2917 C C . GLY A 1 357 ? 10.119 0.366 14.080 1.00 21.77 ? 357 GLY A C 1 ATOM 2918 O O . GLY A 1 357 ? 10.894 0.038 13.178 1.00 22.07 ? 357 GLY A O 1 ATOM 2919 N N . HIS A 1 358 ? 8.820 0.618 13.883 1.00 21.11 ? 358 HIS A N 1 ATOM 2920 C CA . HIS A 1 358 ? 8.171 0.579 12.563 1.00 20.72 ? 358 HIS A CA 1 ATOM 2921 C C . HIS A 1 358 ? 7.883 -0.825 12.069 1.00 20.98 ? 358 HIS A C 1 ATOM 2922 O O . HIS A 1 358 ? 6.716 -1.205 11.956 1.00 21.32 ? 358 HIS A O 1 ATOM 2923 C CB . HIS A 1 358 ? 8.952 1.365 11.504 1.00 20.59 ? 358 HIS A CB 1 ATOM 2924 C CG . HIS A 1 358 ? 9.086 2.817 11.823 1.00 19.83 ? 358 HIS A CG 1 ATOM 2925 N ND1 . HIS A 1 358 ? 8.055 3.713 11.648 1.00 18.19 ? 358 HIS A ND1 1 ATOM 2926 C CD2 . HIS A 1 358 ? 10.117 3.524 12.339 1.00 19.50 ? 358 HIS A CD2 1 ATOM 2927 C CE1 . HIS A 1 358 ? 8.451 4.913 12.028 1.00 19.17 ? 358 HIS A CE1 1 ATOM 2928 N NE2 . HIS A 1 358 ? 9.697 4.827 12.452 1.00 19.58 ? 358 HIS A NE2 1 ATOM 2929 N N . GLY A 1 359 ? 8.931 -1.601 11.788 1.00 20.91 ? 359 GLY A N 1 ATOM 2930 C CA . GLY A 1 359 ? 8.761 -2.966 11.279 1.00 20.88 ? 359 GLY A CA 1 ATOM 2931 C C . GLY A 1 359 ? 7.861 -3.014 10.049 1.00 20.94 ? 359 GLY A C 1 ATOM 2932 O O . GLY A 1 359 ? 7.181 -4.011 9.815 1.00 20.86 ? 359 GLY A O 1 ATOM 2933 N N . PHE A 1 360 ? 7.874 -1.927 9.269 1.00 21.07 ? 360 PHE A N 1 ATOM 2934 C CA . PHE A 1 360 ? 7.010 -1.741 8.094 1.00 20.94 ? 360 PHE A CA 1 ATOM 2935 C C . PHE A 1 360 ? 7.028 -2.930 7.132 1.00 21.45 ? 360 PHE A C 1 ATOM 2936 O O . PHE A 1 360 ? 5.982 -3.335 6.629 1.00 21.62 ? 360 PHE A O 1 ATOM 2937 C CB . PHE A 1 360 ? 7.420 -0.457 7.370 1.00 20.59 ? 360 PHE A CB 1 ATOM 2938 C CG . PHE A 1 360 ? 6.464 -0.009 6.292 1.00 19.42 ? 360 PHE A CG 1 ATOM 2939 C CD1 . PHE A 1 360 ? 6.687 -0.346 4.962 1.00 18.78 ? 360 PHE A CD1 1 ATOM 2940 C CD2 . PHE A 1 360 ? 5.369 0.785 6.598 1.00 18.66 ? 360 PHE A CD2 1 ATOM 2941 C CE1 . PHE A 1 360 ? 5.821 0.080 3.947 1.00 17.15 ? 360 PHE A CE1 1 ATOM 2942 C CE2 . PHE A 1 360 ? 4.504 1.219 5.597 1.00 18.43 ? 360 PHE A CE2 1 ATOM 2943 C CZ . PHE A 1 360 ? 4.736 0.857 4.261 1.00 17.57 ? 360 PHE A CZ 1 ATOM 2944 N N . ALA A 1 361 ? 8.211 -3.496 6.895 1.00 21.83 ? 361 ALA A N 1 ATOM 2945 C CA . ALA A 1 361 ? 8.359 -4.583 5.923 1.00 22.04 ? 361 ALA A CA 1 ATOM 2946 C C . ALA A 1 361 ? 8.096 -5.974 6.512 1.00 22.36 ? 361 ALA A C 1 ATOM 2947 O O . ALA A 1 361 ? 8.321 -6.985 5.836 1.00 22.22 ? 361 ALA A O 1 ATOM 2948 C CB . ALA A 1 361 ? 9.739 -4.521 5.272 1.00 21.98 ? 361 ALA A CB 1 ATOM 2949 N N . LEU A 1 362 ? 7.600 -6.027 7.753 1.00 22.73 ? 362 LEU A N 1 ATOM 2950 C CA . LEU A 1 362 ? 7.452 -7.303 8.464 1.00 23.49 ? 362 LEU A CA 1 ATOM 2951 C C . LEU A 1 362 ? 6.569 -8.341 7.755 1.00 24.05 ? 362 LEU A C 1 ATOM 2952 O O . LEU A 1 362 ? 6.969 -9.506 7.638 1.00 24.29 ? 362 LEU A O 1 ATOM 2953 C CB . LEU A 1 362 ? 6.946 -7.099 9.895 1.00 23.58 ? 362 LEU A CB 1 ATOM 2954 C CG . LEU A 1 362 ? 7.540 -7.950 11.035 1.00 23.23 ? 362 LEU A CG 1 ATOM 2955 C CD1 . LEU A 1 362 ? 6.480 -8.223 12.109 1.00 21.60 ? 362 LEU A CD1 1 ATOM 2956 C CD2 . LEU A 1 362 ? 8.200 -9.254 10.568 1.00 21.56 ? 362 LEU A CD2 1 ATOM 2957 N N . SER A 1 363 ? 5.386 -7.924 7.297 1.00 24.31 ? 363 SER A N 1 ATOM 2958 C CA . SER A 1 363 ? 4.425 -8.825 6.644 1.00 24.73 ? 363 SER A CA 1 ATOM 2959 C C . SER A 1 363 ? 4.933 -9.436 5.329 1.00 25.30 ? 363 SER A C 1 ATOM 2960 O O . SER A 1 363 ? 4.306 -10.335 4.776 1.00 25.61 ? 363 SER A O 1 ATOM 2961 C CB . SER A 1 363 ? 3.108 -8.095 6.387 1.00 24.91 ? 363 SER A CB 1 ATOM 2962 O OG . SER A 1 363 ? 3.302 -6.975 5.529 1.00 24.48 ? 363 SER A OG 1 ATOM 2963 N N . LYS A 1 364 ? 6.055 -8.941 4.817 1.00 25.75 ? 364 LYS A N 1 ATOM 2964 C CA . LYS A 1 364 ? 6.645 -9.522 3.614 1.00 26.29 ? 364 LYS A CA 1 ATOM 2965 C C . LYS A 1 364 ? 7.626 -10.642 3.963 1.00 26.40 ? 364 LYS A C 1 ATOM 2966 O O . LYS A 1 364 ? 8.170 -11.304 3.077 1.00 26.49 ? 364 LYS A O 1 ATOM 2967 C CB . LYS A 1 364 ? 7.314 -8.440 2.756 1.00 26.41 ? 364 LYS A CB 1 ATOM 2968 C CG . LYS A 1 364 ? 6.332 -7.414 2.212 1.00 27.42 ? 364 LYS A CG 1 ATOM 2969 C CD . LYS A 1 364 ? 6.952 -6.552 1.140 1.00 28.73 ? 364 LYS A CD 1 ATOM 2970 C CE . LYS A 1 364 ? 6.183 -5.264 0.959 1.00 30.49 ? 364 LYS A CE 1 ATOM 2971 N NZ . LYS A 1 364 ? 6.160 -4.429 2.207 1.00 32.16 ? 364 LYS A NZ 1 ATOM 2972 N N . HIS A 1 365 ? 7.840 -10.849 5.259 1.00 26.61 ? 365 HIS A N 1 ATOM 2973 C CA . HIS A 1 365 ? 8.748 -11.885 5.746 1.00 26.84 ? 365 HIS A CA 1 ATOM 2974 C C . HIS A 1 365 ? 8.024 -12.793 6.739 1.00 26.77 ? 365 HIS A C 1 ATOM 2975 O O . HIS A 1 365 ? 8.098 -12.569 7.951 1.00 26.78 ? 365 HIS A O 1 ATOM 2976 C CB . HIS A 1 365 ? 9.979 -11.256 6.402 1.00 26.88 ? 365 HIS A CB 1 ATOM 2977 C CG . HIS A 1 365 ? 10.875 -10.532 5.449 1.00 27.67 ? 365 HIS A CG 1 ATOM 2978 N ND1 . HIS A 1 365 ? 10.809 -9.169 5.257 1.00 29.32 ? 365 HIS A ND1 1 ATOM 2979 C CD2 . HIS A 1 365 ? 11.870 -10.977 4.645 1.00 28.20 ? 365 HIS A CD2 1 ATOM 2980 C CE1 . HIS A 1 365 ? 11.721 -8.807 4.370 1.00 29.94 ? 365 HIS A CE1 1 ATOM 2981 N NE2 . HIS A 1 365 ? 12.383 -9.884 3.987 1.00 28.81 ? 365 HIS A NE2 1 ATOM 2982 N N . PRO A 1 366 ? 7.314 -13.817 6.226 1.00 26.89 ? 366 PRO A N 1 ATOM 2983 C CA . PRO A 1 366 ? 6.475 -14.678 7.074 1.00 26.87 ? 366 PRO A CA 1 ATOM 2984 C C . PRO A 1 366 ? 7.239 -15.366 8.220 1.00 26.94 ? 366 PRO A C 1 ATOM 2985 O O . PRO A 1 366 ? 6.718 -15.441 9.331 1.00 27.06 ? 366 PRO A O 1 ATOM 2986 C CB . PRO A 1 366 ? 5.899 -15.704 6.083 1.00 26.77 ? 366 PRO A CB 1 ATOM 2987 C CG . PRO A 1 366 ? 6.799 -15.635 4.881 1.00 27.03 ? 366 PRO A CG 1 ATOM 2988 C CD . PRO A 1 366 ? 7.261 -14.221 4.806 1.00 26.83 ? 366 PRO A CD 1 ATOM 2989 N N . ALA A 1 367 ? 8.461 -15.829 7.958 1.00 27.09 ? 367 ALA A N 1 ATOM 2990 C CA . ALA A 1 367 ? 9.276 -16.538 8.963 1.00 27.40 ? 367 ALA A CA 1 ATOM 2991 C C . ALA A 1 367 ? 9.739 -15.647 10.118 1.00 27.80 ? 367 ALA A C 1 ATOM 2992 O O . ALA A 1 367 ? 9.736 -16.065 11.289 1.00 27.52 ? 367 ALA A O 1 ATOM 2993 C CB . ALA A 1 367 ? 10.477 -17.204 8.304 1.00 27.23 ? 367 ALA A CB 1 ATOM 2994 N N . VAL A 1 368 ? 10.143 -14.423 9.772 1.00 28.29 ? 368 VAL A N 1 ATOM 2995 C CA . VAL A 1 368 ? 10.527 -13.409 10.752 1.00 28.80 ? 368 VAL A CA 1 ATOM 2996 C C . VAL A 1 368 ? 9.290 -12.996 11.553 1.00 29.35 ? 368 VAL A C 1 ATOM 2997 O O . VAL A 1 368 ? 9.357 -12.815 12.770 1.00 29.43 ? 368 VAL A O 1 ATOM 2998 C CB . VAL A 1 368 ? 11.174 -12.181 10.061 1.00 28.87 ? 368 VAL A CB 1 ATOM 2999 C CG1 . VAL A 1 368 ? 11.644 -11.161 11.085 1.00 28.50 ? 368 VAL A CG1 1 ATOM 3000 C CG2 . VAL A 1 368 ? 12.334 -12.614 9.183 1.00 28.41 ? 368 VAL A CG2 1 ATOM 3001 N N . ARG A 1 369 ? 8.163 -12.870 10.857 1.00 29.97 ? 369 ARG A N 1 ATOM 3002 C CA . ARG A 1 369 ? 6.888 -12.553 11.481 1.00 30.93 ? 369 ARG A CA 1 ATOM 3003 C C . ARG A 1 369 ? 6.545 -13.578 12.569 1.00 31.22 ? 369 ARG A C 1 ATOM 3004 O O . ARG A 1 369 ? 6.274 -13.209 13.718 1.00 31.12 ? 369 ARG A O 1 ATOM 3005 C CB . ARG A 1 369 ? 5.792 -12.487 10.415 1.00 31.15 ? 369 ARG A CB 1 ATOM 3006 C CG . ARG A 1 369 ? 4.408 -12.108 10.918 1.00 32.73 ? 369 ARG A CG 1 ATOM 3007 C CD . ARG A 1 369 ? 3.407 -12.253 9.793 1.00 35.91 ? 369 ARG A CD 1 ATOM 3008 N NE . ARG A 1 369 ? 2.035 -12.039 10.238 1.00 38.76 ? 369 ARG A NE 1 ATOM 3009 C CZ . ARG A 1 369 ? 1.008 -11.830 9.417 1.00 40.41 ? 369 ARG A CZ 1 ATOM 3010 N NH1 . ARG A 1 369 ? 1.199 -11.801 8.101 1.00 40.57 ? 369 ARG A NH1 1 ATOM 3011 N NH2 . ARG A 1 369 ? -0.211 -11.642 9.913 1.00 41.04 ? 369 ARG A NH2 1 ATOM 3012 N N . THR A 1 370 ? 6.574 -14.857 12.200 1.00 31.58 ? 370 THR A N 1 ATOM 3013 C CA . THR A 1 370 ? 6.328 -15.947 13.143 1.00 32.27 ? 370 THR A CA 1 ATOM 3014 C C . THR A 1 370 ? 7.302 -15.897 14.330 1.00 32.77 ? 370 THR A C 1 ATOM 3015 O O . THR A 1 370 ? 6.891 -16.066 15.478 1.00 32.90 ? 370 THR A O 1 ATOM 3016 C CB . THR A 1 370 ? 6.424 -17.317 12.440 1.00 32.34 ? 370 THR A CB 1 ATOM 3017 O OG1 . THR A 1 370 ? 5.469 -17.374 11.375 1.00 32.11 ? 370 THR A OG1 1 ATOM 3018 C CG2 . THR A 1 370 ? 6.173 -18.473 13.417 1.00 32.02 ? 370 THR A CG2 1 ATOM 3019 N N . TYR A 1 371 ? 8.578 -15.643 14.046 1.00 33.30 ? 371 TYR A N 1 ATOM 3020 C CA . TYR A 1 371 ? 9.617 -15.642 15.068 1.00 34.10 ? 371 TYR A CA 1 ATOM 3021 C C . TYR A 1 371 ? 9.423 -14.534 16.092 1.00 34.61 ? 371 TYR A C 1 ATOM 3022 O O . TYR A 1 371 ? 9.575 -14.767 17.294 1.00 34.67 ? 371 TYR A O 1 ATOM 3023 C CB . TYR A 1 371 ? 11.005 -15.533 14.429 1.00 34.22 ? 371 TYR A CB 1 ATOM 3024 C CG . TYR A 1 371 ? 12.164 -15.572 15.409 1.00 34.69 ? 371 TYR A CG 1 ATOM 3025 C CD1 . TYR A 1 371 ? 12.765 -14.393 15.850 1.00 35.00 ? 371 TYR A CD1 1 ATOM 3026 C CD2 . TYR A 1 371 ? 12.666 -16.789 15.890 1.00 35.44 ? 371 TYR A CD2 1 ATOM 3027 C CE1 . TYR A 1 371 ? 13.827 -14.416 16.746 1.00 35.22 ? 371 TYR A CE1 1 ATOM 3028 C CE2 . TYR A 1 371 ? 13.740 -16.826 16.785 1.00 35.46 ? 371 TYR A CE2 1 ATOM 3029 C CZ . TYR A 1 371 ? 14.313 -15.634 17.207 1.00 35.95 ? 371 TYR A CZ 1 ATOM 3030 O OH . TYR A 1 371 ? 15.369 -15.651 18.092 1.00 36.33 ? 371 TYR A OH 1 ATOM 3031 N N . SER A 1 372 ? 9.100 -13.334 15.615 1.00 35.32 ? 372 SER A N 1 ATOM 3032 C CA . SER A 1 372 ? 8.890 -12.185 16.501 1.00 36.05 ? 372 SER A CA 1 ATOM 3033 C C . SER A 1 372 ? 7.618 -12.371 17.348 1.00 36.65 ? 372 SER A C 1 ATOM 3034 O O . SER A 1 372 ? 7.579 -11.987 18.518 1.00 36.47 ? 372 SER A O 1 ATOM 3035 C CB . SER A 1 372 ? 8.873 -10.865 15.707 1.00 35.84 ? 372 SER A CB 1 ATOM 3036 O OG . SER A 1 372 ? 7.579 -10.286 15.619 1.00 36.13 ? 372 SER A OG 1 ATOM 3037 N N . TRP A 1 373 ? 6.597 -12.976 16.746 1.00 37.49 ? 373 TRP A N 1 ATOM 3038 C CA . TRP A 1 373 ? 5.359 -13.310 17.442 1.00 38.55 ? 373 TRP A CA 1 ATOM 3039 C C . TRP A 1 373 ? 5.637 -14.327 18.555 1.00 38.39 ? 373 TRP A C 1 ATOM 3040 O O . TRP A 1 373 ? 5.158 -14.177 19.682 1.00 38.25 ? 373 TRP A O 1 ATOM 3041 C CB . TRP A 1 373 ? 4.332 -13.843 16.440 1.00 38.93 ? 373 TRP A CB 1 ATOM 3042 C CG . TRP A 1 373 ? 3.043 -14.284 17.029 1.00 41.83 ? 373 TRP A CG 1 ATOM 3043 C CD1 . TRP A 1 373 ? 1.955 -13.507 17.306 1.00 43.57 ? 373 TRP A CD1 1 ATOM 3044 C CD2 . TRP A 1 373 ? 2.687 -15.623 17.394 1.00 44.78 ? 373 TRP A CD2 1 ATOM 3045 N NE1 . TRP A 1 373 ? 0.941 -14.279 17.832 1.00 45.05 ? 373 TRP A NE1 1 ATOM 3046 C CE2 . TRP A 1 373 ? 1.364 -15.581 17.897 1.00 45.49 ? 373 TRP A CE2 1 ATOM 3047 C CE3 . TRP A 1 373 ? 3.358 -16.855 17.347 1.00 45.56 ? 373 TRP A CE3 1 ATOM 3048 C CZ2 . TRP A 1 373 ? 0.698 -16.725 18.349 1.00 46.80 ? 373 TRP A CZ2 1 ATOM 3049 C CZ3 . TRP A 1 373 ? 2.698 -17.993 17.798 1.00 46.84 ? 373 TRP A CZ3 1 ATOM 3050 C CH2 . TRP A 1 373 ? 1.379 -17.920 18.295 1.00 46.92 ? 373 TRP A CH2 1 ATOM 3051 N N . LYS A 1 374 ? 6.439 -15.339 18.234 1.00 38.29 ? 374 LYS A N 1 ATOM 3052 C CA . LYS A 1 374 ? 6.819 -16.363 19.208 1.00 38.29 ? 374 LYS A CA 1 ATOM 3053 C C . LYS A 1 374 ? 7.683 -15.840 20.356 1.00 37.65 ? 374 LYS A C 1 ATOM 3054 O O . LYS A 1 374 ? 7.484 -16.241 21.498 1.00 37.77 ? 374 LYS A O 1 ATOM 3055 C CB . LYS A 1 374 ? 7.467 -17.577 18.525 1.00 38.58 ? 374 LYS A CB 1 ATOM 3056 C CG . LYS A 1 374 ? 6.433 -18.575 18.024 1.00 40.32 ? 374 LYS A CG 1 ATOM 3057 C CD . LYS A 1 374 ? 7.024 -19.730 17.218 1.00 42.24 ? 374 LYS A CD 1 ATOM 3058 C CE . LYS A 1 374 ? 5.906 -20.702 16.826 1.00 43.79 ? 374 LYS A CE 1 ATOM 3059 N NZ . LYS A 1 374 ? 6.343 -21.772 15.886 1.00 45.07 ? 374 LYS A NZ 1 ATOM 3060 N N . LYS A 1 375 ? 8.621 -14.940 20.062 1.00 36.85 ? 375 LYS A N 1 ATOM 3061 C CA . LYS A 1 375 ? 9.427 -14.299 21.111 1.00 36.11 ? 375 LYS A CA 1 ATOM 3062 C C . LYS A 1 375 ? 8.717 -13.098 21.760 1.00 34.75 ? 375 LYS A C 1 ATOM 3063 O O . LYS A 1 375 ? 9.313 -12.373 22.551 1.00 34.52 ? 375 LYS A O 1 ATOM 3064 C CB . LYS A 1 375 ? 10.802 -13.873 20.572 1.00 36.61 ? 375 LYS A CB 1 ATOM 3065 C CG . LYS A 1 375 ? 11.733 -15.012 20.192 1.00 38.68 ? 375 LYS A CG 1 ATOM 3066 C CD . LYS A 1 375 ? 12.228 -15.773 21.413 1.00 43.22 ? 375 LYS A CD 1 ATOM 3067 C CE . LYS A 1 375 ? 12.967 -17.056 20.999 1.00 45.80 ? 375 LYS A CE 1 ATOM 3068 N NZ . LYS A 1 375 ? 13.169 -18.019 22.133 1.00 47.02 ? 375 LYS A NZ 1 ATOM 3069 N N . ASP A 1 376 ? 7.443 -12.915 21.421 1.00 33.34 ? 376 ASP A N 1 ATOM 3070 C CA . ASP A 1 376 ? 6.629 -11.769 21.846 1.00 32.07 ? 376 ASP A CA 1 ATOM 3071 C C . ASP A 1 376 ? 7.320 -10.391 21.744 1.00 30.81 ? 376 ASP A C 1 ATOM 3072 O O . ASP A 1 376 ? 7.276 -9.587 22.682 1.00 30.70 ? 376 ASP A O 1 ATOM 3073 C CB . ASP A 1 376 ? 6.039 -11.997 23.245 1.00 32.25 ? 376 ASP A CB 1 ATOM 3074 C CG . ASP A 1 376 ? 4.786 -11.175 23.490 1.00 32.89 ? 376 ASP A CG 1 ATOM 3075 O OD1 . ASP A 1 376 ? 4.144 -10.737 22.506 1.00 33.38 ? 376 ASP A OD1 1 ATOM 3076 O OD2 . ASP A 1 376 ? 4.439 -10.966 24.668 1.00 34.08 ? 376 ASP A OD2 1 ATOM 3077 N N . ILE A 1 377 ? 7.942 -10.127 20.595 1.00 29.22 ? 377 ILE A N 1 ATOM 3078 C CA . ILE A 1 377 ? 8.609 -8.845 20.341 1.00 27.70 ? 377 ILE A CA 1 ATOM 3079 C C . ILE A 1 377 ? 7.721 -7.951 19.464 1.00 26.62 ? 377 ILE A C 1 ATOM 3080 O O . ILE A 1 377 ? 7.452 -8.281 18.311 1.00 26.39 ? 377 ILE A O 1 ATOM 3081 C CB . ILE A 1 377 ? 10.010 -9.037 19.701 1.00 27.72 ? 377 ILE A CB 1 ATOM 3082 C CG1 . ILE A 1 377 ? 10.862 -10.025 20.520 1.00 27.63 ? 377 ILE A CG1 1 ATOM 3083 C CG2 . ILE A 1 377 ? 10.716 -7.694 19.491 1.00 27.32 ? 377 ILE A CG2 1 ATOM 3084 C CD1 . ILE A 1 377 ? 11.066 -9.648 21.982 1.00 27.71 ? 377 ILE A CD1 1 ATOM 3085 N N . PRO A 1 378 ? 7.250 -6.822 20.022 1.00 25.59 ? 378 PRO A N 1 ATOM 3086 C CA . PRO A 1 378 ? 6.270 -5.975 19.335 1.00 25.04 ? 378 PRO A CA 1 ATOM 3087 C C . PRO A 1 378 ? 6.869 -4.990 18.324 1.00 24.71 ? 378 PRO A C 1 ATOM 3088 O O . PRO A 1 378 ? 8.034 -4.571 18.459 1.00 24.99 ? 378 PRO A O 1 ATOM 3089 C CB . PRO A 1 378 ? 5.640 -5.190 20.483 1.00 24.90 ? 378 PRO A CB 1 ATOM 3090 C CG . PRO A 1 378 ? 6.730 -5.076 21.489 1.00 24.78 ? 378 PRO A CG 1 ATOM 3091 C CD . PRO A 1 378 ? 7.548 -6.329 21.382 1.00 25.14 ? 378 PRO A CD 1 ATOM 3092 N N . ILE A 1 379 ? 6.073 -4.614 17.326 1.00 23.78 ? 379 ILE A N 1 ATOM 3093 C CA . ILE A 1 379 ? 6.439 -3.495 16.460 1.00 22.89 ? 379 ILE A CA 1 ATOM 3094 C C . ILE A 1 379 ? 5.794 -2.195 16.959 1.00 22.64 ? 379 ILE A C 1 ATOM 3095 O O . ILE A 1 379 ? 4.710 -2.209 17.531 1.00 22.24 ? 379 ILE A O 1 ATOM 3096 C CB . ILE A 1 379 ? 6.135 -3.748 14.953 1.00 22.79 ? 379 ILE A CB 1 ATOM 3097 C CG1 . ILE A 1 379 ? 4.671 -4.134 14.720 1.00 22.26 ? 379 ILE A CG1 1 ATOM 3098 C CG2 . ILE A 1 379 ? 7.077 -4.813 14.381 1.00 22.52 ? 379 ILE A CG2 1 ATOM 3099 C CD1 . ILE A 1 379 ? 4.214 -3.967 13.275 1.00 21.55 ? 379 ILE A CD1 1 ATOM 3100 N N . GLU A 1 380 ? 6.499 -1.085 16.777 1.00 22.40 ? 380 GLU A N 1 ATOM 3101 C CA . GLU A 1 380 ? 5.991 0.225 17.136 1.00 22.60 ? 380 GLU A CA 1 ATOM 3102 C C . GLU A 1 380 ? 5.513 0.890 15.852 1.00 22.83 ? 380 GLU A C 1 ATOM 3103 O O . GLU A 1 380 ? 6.329 1.353 15.047 1.00 23.01 ? 380 GLU A O 1 ATOM 3104 C CB . GLU A 1 380 ? 7.082 1.081 17.796 1.00 22.40 ? 380 GLU A CB 1 ATOM 3105 C CG . GLU A 1 380 ? 7.714 0.489 19.056 1.00 22.71 ? 380 GLU A CG 1 ATOM 3106 C CD . GLU A 1 380 ? 9.101 1.049 19.337 1.00 23.51 ? 380 GLU A CD 1 ATOM 3107 O OE1 . GLU A 1 380 ? 9.856 1.336 18.384 1.00 25.11 ? 380 GLU A OE1 1 ATOM 3108 O OE2 . GLU A 1 380 ? 9.454 1.210 20.512 1.00 22.69 ? 380 GLU A OE2 1 ATOM 3109 N N . VAL A 1 381 ? 4.198 0.924 15.651 1.00 22.76 ? 381 VAL A N 1 ATOM 3110 C CA . VAL A 1 381 ? 3.637 1.459 14.412 1.00 22.64 ? 381 VAL A CA 1 ATOM 3111 C C . VAL A 1 381 ? 3.253 2.934 14.535 1.00 22.78 ? 381 VAL A C 1 ATOM 3112 O O . VAL A 1 381 ? 2.554 3.337 15.465 1.00 22.57 ? 381 VAL A O 1 ATOM 3113 C CB . VAL A 1 381 ? 2.526 0.531 13.785 1.00 22.64 ? 381 VAL A CB 1 ATOM 3114 C CG1 . VAL A 1 381 ? 2.005 -0.484 14.781 1.00 22.35 ? 381 VAL A CG1 1 ATOM 3115 C CG2 . VAL A 1 381 ? 1.397 1.321 13.131 1.00 22.10 ? 381 VAL A CG2 1 ATOM 3116 N N . CYS A 1 382 ? 3.769 3.718 13.588 1.00 23.28 ? 382 CYS A N 1 ATOM 3117 C CA . CYS A 1 382 ? 3.609 5.173 13.522 1.00 23.92 ? 382 CYS A CA 1 ATOM 3118 C C . CYS A 1 382 ? 2.996 5.584 12.166 1.00 23.79 ? 382 CYS A C 1 ATOM 3119 O O . CYS A 1 382 ? 3.725 5.958 11.240 1.00 24.08 ? 382 CYS A O 1 ATOM 3120 C CB . CYS A 1 382 ? 4.967 5.841 13.701 1.00 23.91 ? 382 CYS A CB 1 ATOM 3121 S SG . CYS A 1 382 ? 5.781 5.447 15.254 1.00 26.53 ? 382 CYS A SG 1 ATOM 3122 N N . PRO A 1 383 ? 1.657 5.507 12.044 1.00 23.57 ? 383 PRO A N 1 ATOM 3123 C CA . PRO A 1 383 ? 1.014 5.657 10.742 1.00 23.25 ? 383 PRO A CA 1 ATOM 3124 C C . PRO A 1 383 ? 1.247 7.009 10.052 1.00 22.90 ? 383 PRO A C 1 ATOM 3125 O O . PRO A 1 383 ? 1.545 7.028 8.862 1.00 22.96 ? 383 PRO A O 1 ATOM 3126 C CB . PRO A 1 383 ? -0.478 5.446 11.053 1.00 23.41 ? 383 PRO A CB 1 ATOM 3127 C CG . PRO A 1 383 ? -0.615 5.714 12.504 1.00 23.71 ? 383 PRO A CG 1 ATOM 3128 C CD . PRO A 1 383 ? 0.671 5.262 13.115 1.00 23.65 ? 383 PRO A CD 1 ATOM 3129 N N . ILE A 1 384 ? 1.119 8.120 10.777 1.00 22.33 ? 384 ILE A N 1 ATOM 3130 C CA . ILE A 1 384 ? 1.265 9.442 10.164 1.00 21.80 ? 384 ILE A CA 1 ATOM 3131 C C . ILE A 1 384 ? 2.681 9.642 9.613 1.00 21.89 ? 384 ILE A C 1 ATOM 3132 O O . ILE A 1 384 ? 2.860 10.116 8.483 1.00 21.91 ? 384 ILE A O 1 ATOM 3133 C CB . ILE A 1 384 ? 0.851 10.580 11.124 1.00 21.56 ? 384 ILE A CB 1 ATOM 3134 C CG1 . ILE A 1 384 ? -0.659 10.517 11.383 1.00 21.33 ? 384 ILE A CG1 1 ATOM 3135 C CG2 . ILE A 1 384 ? 1.214 11.934 10.544 1.00 20.93 ? 384 ILE A CG2 1 ATOM 3136 C CD1 . ILE A 1 384 ? -1.154 11.443 12.467 1.00 20.36 ? 384 ILE A CD1 1 ATOM 3137 N N . SER A 1 385 ? 3.679 9.259 10.401 1.00 21.70 ? 385 SER A N 1 ATOM 3138 C CA . SER A 1 385 ? 5.063 9.288 9.954 1.00 21.53 ? 385 SER A CA 1 ATOM 3139 C C . SER A 1 385 ? 5.268 8.549 8.627 1.00 21.40 ? 385 SER A C 1 ATOM 3140 O O . SER A 1 385 ? 5.842 9.112 7.692 1.00 21.54 ? 385 SER A O 1 ATOM 3141 C CB . SER A 1 385 ? 5.982 8.708 11.023 1.00 21.58 ? 385 SER A CB 1 ATOM 3142 O OG . SER A 1 385 ? 7.304 8.700 10.547 1.00 22.12 ? 385 SER A OG 1 ATOM 3143 N N . ASN A 1 386 ? 4.791 7.302 8.550 1.00 21.10 ? 386 ASN A N 1 ATOM 3144 C CA . ASN A 1 386 ? 4.916 6.478 7.341 1.00 20.56 ? 386 ASN A CA 1 ATOM 3145 C C . ASN A 1 386 ? 4.274 7.125 6.109 1.00 20.61 ? 386 ASN A C 1 ATOM 3146 O O . ASN A 1 386 ? 4.758 6.944 4.981 1.00 20.58 ? 386 ASN A O 1 ATOM 3147 C CB . ASN A 1 386 ? 4.321 5.081 7.551 1.00 20.48 ? 386 ASN A CB 1 ATOM 3148 C CG . ASN A 1 386 ? 5.011 4.280 8.677 1.00 20.60 ? 386 ASN A CG 1 ATOM 3149 O OD1 . ASN A 1 386 ? 4.436 3.314 9.192 1.00 19.63 ? 386 ASN A OD1 1 ATOM 3150 N ND2 . ASN A 1 386 ? 6.234 4.675 9.056 1.00 18.85 ? 386 ASN A ND2 1 ATOM 3151 N N . GLN A 1 387 ? 3.190 7.871 6.314 1.00 20.14 ? 387 GLN A N 1 ATOM 3152 C CA . GLN A 1 387 ? 2.541 8.577 5.213 1.00 19.98 ? 387 GLN A CA 1 ATOM 3153 C C . GLN A 1 387 ? 3.355 9.796 4.795 1.00 19.99 ? 387 GLN A C 1 ATOM 3154 O O . GLN A 1 387 ? 3.661 9.966 3.620 1.00 20.02 ? 387 GLN A O 1 ATOM 3155 C CB . GLN A 1 387 ? 1.126 9.008 5.597 1.00 20.08 ? 387 GLN A CB 1 ATOM 3156 C CG . GLN A 1 387 ? 0.281 9.536 4.439 1.00 19.02 ? 387 GLN A CG 1 ATOM 3157 C CD . GLN A 1 387 ? -1.164 9.769 4.847 1.00 18.15 ? 387 GLN A CD 1 ATOM 3158 O OE1 . GLN A 1 387 ? -1.449 10.605 5.693 1.00 18.01 ? 387 GLN A OE1 1 ATOM 3159 N NE2 . GLN A 1 387 ? -2.080 9.033 4.241 1.00 16.58 ? 387 GLN A NE2 1 ATOM 3160 N N . VAL A 1 388 ? 3.705 10.628 5.771 1.00 19.90 ? 388 VAL A N 1 ATOM 3161 C CA . VAL A 1 388 ? 4.403 11.875 5.514 1.00 19.87 ? 388 VAL A CA 1 ATOM 3162 C C . VAL A 1 388 ? 5.763 11.594 4.875 1.00 19.82 ? 388 VAL A C 1 ATOM 3163 O O . VAL A 1 388 ? 6.159 12.282 3.926 1.00 19.57 ? 388 VAL A O 1 ATOM 3164 C CB . VAL A 1 388 ? 4.507 12.759 6.803 1.00 20.05 ? 388 VAL A CB 1 ATOM 3165 C CG1 . VAL A 1 388 ? 5.388 13.985 6.578 1.00 19.87 ? 388 VAL A CG1 1 ATOM 3166 C CG2 . VAL A 1 388 ? 3.118 13.203 7.258 1.00 20.04 ? 388 VAL A CG2 1 ATOM 3167 N N . LEU A 1 389 ? 6.461 10.568 5.373 1.00 19.68 ? 389 LEU A N 1 ATOM 3168 C CA . LEU A 1 389 ? 7.775 10.193 4.824 1.00 19.35 ? 389 LEU A CA 1 ATOM 3169 C C . LEU A 1 389 ? 7.676 9.289 3.592 1.00 19.43 ? 389 LEU A C 1 ATOM 3170 O O . LEU A 1 389 ? 8.674 8.714 3.136 1.00 19.57 ? 389 LEU A O 1 ATOM 3171 C CB . LEU A 1 389 ? 8.688 9.593 5.904 1.00 19.22 ? 389 LEU A CB 1 ATOM 3172 C CG . LEU A 1 389 ? 9.011 10.522 7.092 1.00 19.38 ? 389 LEU A CG 1 ATOM 3173 C CD1 . LEU A 1 389 ? 9.903 9.844 8.130 1.00 18.11 ? 389 LEU A CD1 1 ATOM 3174 C CD2 . LEU A 1 389 ? 9.635 11.823 6.635 1.00 18.59 ? 389 LEU A CD2 1 ATOM 3175 N N . LYS A 1 390 ? 6.457 9.177 3.062 1.00 19.46 ? 390 LYS A N 1 ATOM 3176 C CA . LYS A 1 390 ? 6.188 8.643 1.723 1.00 19.34 ? 390 LYS A CA 1 ATOM 3177 C C . LYS A 1 390 ? 6.407 7.130 1.526 1.00 19.50 ? 390 LYS A C 1 ATOM 3178 O O . LYS A 1 390 ? 6.605 6.675 0.392 1.00 19.77 ? 390 LYS A O 1 ATOM 3179 C CB . LYS A 1 390 ? 6.918 9.471 0.653 1.00 19.34 ? 390 LYS A CB 1 ATOM 3180 C CG . LYS A 1 390 ? 6.509 10.950 0.627 1.00 19.66 ? 390 LYS A CG 1 ATOM 3181 C CD . LYS A 1 390 ? 7.433 11.796 -0.253 1.00 20.43 ? 390 LYS A CD 1 ATOM 3182 C CE . LYS A 1 390 ? 7.376 11.390 -1.734 1.00 21.37 ? 390 LYS A CE 1 ATOM 3183 N NZ . LYS A 1 390 ? 6.012 11.560 -2.325 1.00 22.36 ? 390 LYS A NZ 1 ATOM 3184 N N . LEU A 1 391 ? 6.337 6.358 2.616 1.00 19.24 ? 391 LEU A N 1 ATOM 3185 C CA . LEU A 1 391 ? 6.316 4.894 2.535 1.00 18.96 ? 391 LEU A CA 1 ATOM 3186 C C . LEU A 1 391 ? 4.995 4.370 1.986 1.00 19.36 ? 391 LEU A C 1 ATOM 3187 O O . LEU A 1 391 ? 4.953 3.279 1.414 1.00 19.45 ? 391 LEU A O 1 ATOM 3188 C CB . LEU A 1 391 ? 6.585 4.272 3.903 1.00 18.77 ? 391 LEU A CB 1 ATOM 3189 C CG . LEU A 1 391 ? 7.995 3.893 4.401 1.00 18.32 ? 391 LEU A CG 1 ATOM 3190 C CD1 . LEU A 1 391 ? 9.135 4.380 3.543 1.00 15.90 ? 391 LEU A CD1 1 ATOM 3191 C CD2 . LEU A 1 391 ? 8.167 4.353 5.834 1.00 17.45 ? 391 LEU A CD2 1 ATOM 3192 N N . VAL A 1 392 ? 3.919 5.136 2.157 1.00 19.64 ? 392 VAL A N 1 ATOM 3193 C CA . VAL A 1 392 ? 2.589 4.704 1.728 1.00 20.28 ? 392 VAL A CA 1 ATOM 3194 C C . VAL A 1 392 ? 1.652 5.915 1.575 1.00 21.15 ? 392 VAL A C 1 ATOM 3195 O O . VAL A 1 392 ? 1.593 6.779 2.457 1.00 21.37 ? 392 VAL A O 1 ATOM 3196 C CB . VAL A 1 392 ? 1.994 3.601 2.695 1.00 20.35 ? 392 VAL A CB 1 ATOM 3197 C CG1 . VAL A 1 392 ? 1.607 4.184 4.064 1.00 20.20 ? 392 VAL A CG1 1 ATOM 3198 C CG2 . VAL A 1 392 ? 0.801 2.881 2.062 1.00 19.61 ? 392 VAL A CG2 1 ATOM 3199 N N . SER A 1 393 ? 0.942 5.985 0.450 1.00 21.97 ? 393 SER A N 1 ATOM 3200 C CA . SER A 1 393 ? 0.017 7.093 0.178 1.00 23.02 ? 393 SER A CA 1 ATOM 3201 C C . SER A 1 393 ? -1.283 7.002 0.980 1.00 23.30 ? 393 SER A C 1 ATOM 3202 O O . SER A 1 393 ? -1.601 7.884 1.770 1.00 23.76 ? 393 SER A O 1 ATOM 3203 C CB . SER A 1 393 ? -0.340 7.132 -1.304 1.00 23.12 ? 393 SER A CB 1 ATOM 3204 O OG . SER A 1 393 ? 0.590 7.897 -2.035 1.00 24.87 ? 393 SER A OG 1 ATOM 3205 N N . ASP A 1 394 ? -2.015 5.920 0.747 1.00 23.49 ? 394 ASP A N 1 ATOM 3206 C CA . ASP A 1 394 ? -3.331 5.671 1.296 1.00 23.65 ? 394 ASP A CA 1 ATOM 3207 C C . ASP A 1 394 ? -3.157 4.685 2.447 1.00 23.33 ? 394 ASP A C 1 ATOM 3208 O O . ASP A 1 394 ? -2.822 3.529 2.228 1.00 23.59 ? 394 ASP A O 1 ATOM 3209 C CB . ASP A 1 394 ? -4.183 5.073 0.161 1.00 23.93 ? 394 ASP A CB 1 ATOM 3210 C CG . ASP A 1 394 ? -5.615 4.692 0.575 1.00 25.30 ? 394 ASP A CG 1 ATOM 3211 O OD1 . ASP A 1 394 ? -5.968 4.644 1.784 1.00 25.67 ? 394 ASP A OD1 1 ATOM 3212 O OD2 . ASP A 1 394 ? -6.399 4.409 -0.361 1.00 25.52 ? 394 ASP A OD2 1 ATOM 3213 N N . LEU A 1 395 ? -3.391 5.145 3.673 1.00 23.16 ? 395 LEU A N 1 ATOM 3214 C CA . LEU A 1 395 ? -3.184 4.326 4.880 1.00 22.56 ? 395 LEU A CA 1 ATOM 3215 C C . LEU A 1 395 ? -4.085 3.086 4.975 1.00 22.58 ? 395 LEU A C 1 ATOM 3216 O O . LEU A 1 395 ? -3.824 2.178 5.772 1.00 22.66 ? 395 LEU A O 1 ATOM 3217 C CB . LEU A 1 395 ? -3.302 5.179 6.142 1.00 22.20 ? 395 LEU A CB 1 ATOM 3218 C CG . LEU A 1 395 ? -2.129 6.126 6.410 1.00 21.40 ? 395 LEU A CG 1 ATOM 3219 C CD1 . LEU A 1 395 ? -2.538 7.135 7.457 1.00 19.72 ? 395 LEU A CD1 1 ATOM 3220 C CD2 . LEU A 1 395 ? -0.859 5.360 6.838 1.00 21.36 ? 395 LEU A CD2 1 ATOM 3221 N N . ARG A 1 396 ? -5.130 3.038 4.154 1.00 22.15 ? 396 ARG A N 1 ATOM 3222 C CA . ARG A 1 396 ? -5.869 1.794 3.967 1.00 21.88 ? 396 ARG A CA 1 ATOM 3223 C C . ARG A 1 396 ? -4.950 0.675 3.423 1.00 21.78 ? 396 ARG A C 1 ATOM 3224 O O . ARG A 1 396 ? -5.209 -0.505 3.664 1.00 21.89 ? 396 ARG A O 1 ATOM 3225 C CB . ARG A 1 396 ? -7.100 2.000 3.064 1.00 21.89 ? 396 ARG A CB 1 ATOM 3226 C CG . ARG A 1 396 ? -8.273 2.752 3.730 1.00 21.07 ? 396 ARG A CG 1 ATOM 3227 C CD . ARG A 1 396 ? -9.418 2.983 2.763 1.00 19.81 ? 396 ARG A CD 1 ATOM 3228 N NE . ARG A 1 396 ? -8.977 3.722 1.578 1.00 21.22 ? 396 ARG A NE 1 ATOM 3229 C CZ . ARG A 1 396 ? -9.751 4.043 0.541 1.00 20.49 ? 396 ARG A CZ 1 ATOM 3230 N NH1 . ARG A 1 396 ? -11.032 3.712 0.534 1.00 22.15 ? 396 ARG A NH1 1 ATOM 3231 N NH2 . ARG A 1 396 ? -9.241 4.706 -0.494 1.00 19.86 ? 396 ARG A NH2 1 ATOM 3232 N N . ASN A 1 397 ? -3.874 1.052 2.722 1.00 21.24 ? 397 ASN A N 1 ATOM 3233 C CA . ASN A 1 397 ? -2.896 0.099 2.197 1.00 20.79 ? 397 ASN A CA 1 ATOM 3234 C C . ASN A 1 397 ? -1.712 -0.166 3.128 1.00 20.77 ? 397 ASN A C 1 ATOM 3235 O O . ASN A 1 397 ? -0.726 -0.796 2.720 1.00 20.60 ? 397 ASN A O 1 ATOM 3236 C CB . ASN A 1 397 ? -2.356 0.581 0.853 1.00 21.12 ? 397 ASN A CB 1 ATOM 3237 C CG . ASN A 1 397 ? -3.356 0.419 -0.279 1.00 21.78 ? 397 ASN A CG 1 ATOM 3238 O OD1 . ASN A 1 397 ? -3.499 1.308 -1.120 1.00 23.23 ? 397 ASN A OD1 1 ATOM 3239 N ND2 . ASN A 1 397 ? -4.061 -0.708 -0.301 1.00 21.21 ? 397 ASN A ND2 1 ATOM 3240 N N . HIS A 1 398 ? -1.781 0.320 4.364 1.00 20.26 ? 398 HIS A N 1 ATOM 3241 C CA . HIS A 1 398 ? -0.686 0.102 5.302 1.00 20.28 ? 398 HIS A CA 1 ATOM 3242 C C . HIS A 1 398 ? -0.499 -1.399 5.588 1.00 20.27 ? 398 HIS A C 1 ATOM 3243 O O . HIS A 1 398 ? -1.468 -2.104 5.874 1.00 20.31 ? 398 HIS A O 1 ATOM 3244 C CB . HIS A 1 398 ? -0.901 0.878 6.597 1.00 19.88 ? 398 HIS A CB 1 ATOM 3245 C CG . HIS A 1 398 ? 0.362 1.132 7.356 1.00 20.09 ? 398 HIS A CG 1 ATOM 3246 N ND1 . HIS A 1 398 ? 1.023 0.146 8.054 1.00 19.71 ? 398 HIS A ND1 1 ATOM 3247 C CD2 . HIS A 1 398 ? 1.088 2.263 7.527 1.00 20.43 ? 398 HIS A CD2 1 ATOM 3248 C CE1 . HIS A 1 398 ? 2.097 0.658 8.628 1.00 20.02 ? 398 HIS A CE1 1 ATOM 3249 N NE2 . HIS A 1 398 ? 2.160 1.941 8.320 1.00 20.25 ? 398 HIS A NE2 1 ATOM 3250 N N . PRO A 1 399 ? 0.744 -1.897 5.479 1.00 20.15 ? 399 PRO A N 1 ATOM 3251 C CA . PRO A 1 399 ? 1.023 -3.322 5.687 1.00 20.25 ? 399 PRO A CA 1 ATOM 3252 C C . PRO A 1 399 ? 0.688 -3.833 7.091 1.00 20.52 ? 399 PRO A C 1 ATOM 3253 O O . PRO A 1 399 ? 0.652 -5.035 7.306 1.00 20.98 ? 399 PRO A O 1 ATOM 3254 C CB . PRO A 1 399 ? 2.532 -3.426 5.441 1.00 20.08 ? 399 PRO A CB 1 ATOM 3255 C CG . PRO A 1 399 ? 3.051 -2.047 5.554 1.00 19.65 ? 399 PRO A CG 1 ATOM 3256 C CD . PRO A 1 399 ? 1.949 -1.172 5.044 1.00 19.97 ? 399 PRO A CD 1 ATOM 3257 N N . VAL A 1 400 ? 0.445 -2.935 8.035 1.00 20.40 ? 400 VAL A N 1 ATOM 3258 C CA . VAL A 1 400 ? 0.102 -3.350 9.390 1.00 20.57 ? 400 VAL A CA 1 ATOM 3259 C C . VAL A 1 400 ? -1.333 -3.878 9.492 1.00 20.85 ? 400 VAL A C 1 ATOM 3260 O O . VAL A 1 400 ? -1.657 -4.628 10.421 1.00 20.96 ? 400 VAL A O 1 ATOM 3261 C CB . VAL A 1 400 ? 0.412 -2.242 10.422 1.00 20.44 ? 400 VAL A CB 1 ATOM 3262 C CG1 . VAL A 1 400 ? -0.264 -2.515 11.753 1.00 20.43 ? 400 VAL A CG1 1 ATOM 3263 C CG2 . VAL A 1 400 ? 1.924 -2.139 10.624 1.00 20.45 ? 400 VAL A CG2 1 ATOM 3264 N N . ALA A 1 401 ? -2.170 -3.518 8.515 1.00 21.18 ? 401 ALA A N 1 ATOM 3265 C CA . ALA A 1 401 ? -3.541 -4.031 8.419 1.00 21.41 ? 401 ALA A CA 1 ATOM 3266 C C . ALA A 1 401 ? -3.571 -5.559 8.503 1.00 21.81 ? 401 ALA A C 1 ATOM 3267 O O . ALA A 1 401 ? -4.417 -6.132 9.187 1.00 22.09 ? 401 ALA A O 1 ATOM 3268 C CB . ALA A 1 401 ? -4.219 -3.540 7.135 1.00 20.65 ? 401 ALA A CB 1 ATOM 3269 N N . THR A 1 402 ? -2.637 -6.205 7.808 1.00 22.35 ? 402 THR A N 1 ATOM 3270 C CA . THR A 1 402 ? -2.490 -7.659 7.829 1.00 23.03 ? 402 THR A CA 1 ATOM 3271 C C . THR A 1 402 ? -2.115 -8.159 9.228 1.00 22.79 ? 402 THR A C 1 ATOM 3272 O O . THR A 1 402 ? -2.638 -9.166 9.700 1.00 22.61 ? 402 THR A O 1 ATOM 3273 C CB . THR A 1 402 ? -1.438 -8.109 6.788 1.00 23.12 ? 402 THR A CB 1 ATOM 3274 O OG1 . THR A 1 402 ? -1.991 -7.964 5.478 1.00 24.31 ? 402 THR A OG1 1 ATOM 3275 C CG2 . THR A 1 402 ? -1.072 -9.550 6.979 1.00 24.34 ? 402 THR A CG2 1 ATOM 3276 N N . LEU A 1 403 ? -1.230 -7.428 9.895 1.00 23.06 ? 403 LEU A N 1 ATOM 3277 C CA . LEU A 1 403 ? -0.765 -7.801 11.231 1.00 23.05 ? 403 LEU A CA 1 ATOM 3278 C C . LEU A 1 403 ? -1.858 -7.650 12.287 1.00 23.33 ? 403 LEU A C 1 ATOM 3279 O O . LEU A 1 403 ? -1.943 -8.449 13.226 1.00 23.15 ? 403 LEU A O 1 ATOM 3280 C CB . LEU A 1 403 ? 0.480 -6.999 11.600 1.00 22.81 ? 403 LEU A CB 1 ATOM 3281 C CG . LEU A 1 403 ? 1.841 -7.544 11.135 1.00 22.35 ? 403 LEU A CG 1 ATOM 3282 C CD1 . LEU A 1 403 ? 1.752 -8.463 9.930 1.00 21.24 ? 403 LEU A CD1 1 ATOM 3283 C CD2 . LEU A 1 403 ? 2.820 -6.420 10.878 1.00 20.70 ? 403 LEU A CD2 1 ATOM 3284 N N . MET A 1 404 ? -2.705 -6.641 12.120 1.00 23.64 ? 404 MET A N 1 ATOM 3285 C CA . MET A 1 404 ? -3.832 -6.464 13.026 1.00 24.50 ? 404 MET A CA 1 ATOM 3286 C C . MET A 1 404 ? -4.823 -7.618 12.883 1.00 24.65 ? 404 MET A C 1 ATOM 3287 O O . MET A 1 404 ? -5.363 -8.103 13.872 1.00 24.57 ? 404 MET A O 1 ATOM 3288 C CB . MET A 1 404 ? -4.521 -5.119 12.797 1.00 24.47 ? 404 MET A CB 1 ATOM 3289 C CG . MET A 1 404 ? -3.647 -3.912 13.122 1.00 25.55 ? 404 MET A CG 1 ATOM 3290 S SD . MET A 1 404 ? -4.528 -2.367 12.829 1.00 28.07 ? 404 MET A SD 1 ATOM 3291 C CE . MET A 1 404 ? -5.740 -2.430 14.163 1.00 28.61 ? 404 MET A CE 1 ATOM 3292 N N . ALA A 1 405 ? -5.023 -8.070 11.648 1.00 24.99 ? 405 ALA A N 1 ATOM 3293 C CA . ALA A 1 405 ? -5.986 -9.120 11.347 1.00 25.45 ? 405 ALA A CA 1 ATOM 3294 C C . ALA A 1 405 ? -5.638 -10.456 12.015 1.00 25.91 ? 405 ALA A C 1 ATOM 3295 O O . ALA A 1 405 ? -6.518 -11.292 12.222 1.00 26.03 ? 405 ALA A O 1 ATOM 3296 C CB . ALA A 1 405 ? -6.142 -9.288 9.842 1.00 25.26 ? 405 ALA A CB 1 ATOM 3297 N N . THR A 1 406 ? -4.366 -10.649 12.358 1.00 26.10 ? 406 THR A N 1 ATOM 3298 C CA . THR A 1 406 ? -3.937 -11.854 13.067 1.00 26.39 ? 406 THR A CA 1 ATOM 3299 C C . THR A 1 406 ? -3.552 -11.566 14.513 1.00 26.57 ? 406 THR A C 1 ATOM 3300 O O . THR A 1 406 ? -3.005 -12.437 15.189 1.00 27.11 ? 406 THR A O 1 ATOM 3301 C CB . THR A 1 406 ? -2.735 -12.546 12.371 1.00 26.56 ? 406 THR A CB 1 ATOM 3302 O OG1 . THR A 1 406 ? -1.594 -11.677 12.392 1.00 27.05 ? 406 THR A OG1 1 ATOM 3303 C CG2 . THR A 1 406 ? -3.066 -12.905 10.933 1.00 26.58 ? 406 THR A CG2 1 ATOM 3304 N N . GLY A 1 407 ? -3.821 -10.343 14.976 1.00 26.42 ? 407 GLY A N 1 ATOM 3305 C CA . GLY A 1 407 ? -3.574 -9.938 16.359 1.00 25.80 ? 407 GLY A CA 1 ATOM 3306 C C . GLY A 1 407 ? -2.112 -9.938 16.762 1.00 25.96 ? 407 GLY A C 1 ATOM 3307 O O . GLY A 1 407 ? -1.778 -10.301 17.892 1.00 25.84 ? 407 GLY A O 1 ATOM 3308 N N . HIS A 1 408 ? -1.240 -9.511 15.841 1.00 25.87 ? 408 HIS A N 1 ATOM 3309 C CA . HIS A 1 408 ? 0.202 -9.442 16.075 1.00 25.24 ? 408 HIS A CA 1 ATOM 3310 C C . HIS A 1 408 ? 0.524 -8.472 17.228 1.00 25.15 ? 408 HIS A C 1 ATOM 3311 O O . HIS A 1 408 ? -0.197 -7.491 17.416 1.00 25.22 ? 408 HIS A O 1 ATOM 3312 C CB . HIS A 1 408 ? 0.911 -9.025 14.781 1.00 25.21 ? 408 HIS A CB 1 ATOM 3313 C CG . HIS A 1 408 ? 2.391 -9.241 14.805 1.00 25.40 ? 408 HIS A CG 1 ATOM 3314 N ND1 . HIS A 1 408 ? 2.969 -10.458 14.511 1.00 25.11 ? 408 HIS A ND1 1 ATOM 3315 C CD2 . HIS A 1 408 ? 3.409 -8.405 15.117 1.00 24.66 ? 408 HIS A CD2 1 ATOM 3316 C CE1 . HIS A 1 408 ? 4.281 -10.357 14.631 1.00 24.61 ? 408 HIS A CE1 1 ATOM 3317 N NE2 . HIS A 1 408 ? 4.573 -9.122 14.994 1.00 23.73 ? 408 HIS A NE2 1 ATOM 3318 N N . PRO A 1 409 ? 1.581 -8.760 18.026 1.00 24.95 ? 409 PRO A N 1 ATOM 3319 C CA . PRO A 1 409 ? 1.980 -7.831 19.098 1.00 24.68 ? 409 PRO A CA 1 ATOM 3320 C C . PRO A 1 409 ? 2.502 -6.501 18.555 1.00 24.73 ? 409 PRO A C 1 ATOM 3321 O O . PRO A 1 409 ? 3.484 -6.467 17.796 1.00 24.78 ? 409 PRO A O 1 ATOM 3322 C CB . PRO A 1 409 ? 3.104 -8.584 19.828 1.00 24.92 ? 409 PRO A CB 1 ATOM 3323 C CG . PRO A 1 409 ? 3.595 -9.603 18.853 1.00 24.66 ? 409 PRO A CG 1 ATOM 3324 C CD . PRO A 1 409 ? 2.385 -9.997 18.053 1.00 24.75 ? 409 PRO A CD 1 ATOM 3325 N N . MET A 1 410 ? 1.835 -5.418 18.932 1.00 24.49 ? 410 MET A N 1 ATOM 3326 C CA . MET A 1 410 ? 2.182 -4.088 18.442 1.00 24.31 ? 410 MET A CA 1 ATOM 3327 C C . MET A 1 410 ? 1.715 -2.991 19.398 1.00 24.34 ? 410 MET A C 1 ATOM 3328 O O . MET A 1 410 ? 0.780 -3.187 20.185 1.00 24.02 ? 410 MET A O 1 ATOM 3329 C CB . MET A 1 410 ? 1.570 -3.851 17.062 1.00 24.13 ? 410 MET A CB 1 ATOM 3330 C CG . MET A 1 410 ? 0.059 -3.683 17.067 1.00 24.50 ? 410 MET A CG 1 ATOM 3331 S SD . MET A 1 410 ? -0.646 -3.589 15.411 1.00 25.58 ? 410 MET A SD 1 ATOM 3332 C CE . MET A 1 410 ? -0.486 -5.288 14.857 1.00 23.79 ? 410 MET A CE 1 ATOM 3333 N N . VAL A 1 411 ? 2.378 -1.840 19.313 1.00 24.12 ? 411 VAL A N 1 ATOM 3334 C CA . VAL A 1 411 ? 1.956 -0.635 20.012 1.00 24.08 ? 411 VAL A CA 1 ATOM 3335 C C . VAL A 1 411 ? 1.857 0.508 18.994 1.00 24.22 ? 411 VAL A C 1 ATOM 3336 O O . VAL A 1 411 ? 2.512 0.465 17.946 1.00 24.30 ? 411 VAL A O 1 ATOM 3337 C CB . VAL A 1 411 ? 2.908 -0.283 21.196 1.00 24.15 ? 411 VAL A CB 1 ATOM 3338 C CG1 . VAL A 1 411 ? 2.914 -1.396 22.241 1.00 24.32 ? 411 VAL A CG1 1 ATOM 3339 C CG2 . VAL A 1 411 ? 4.329 -0.016 20.716 1.00 23.60 ? 411 VAL A CG2 1 ATOM 3340 N N . ILE A 1 412 ? 1.032 1.510 19.289 1.00 24.02 ? 412 ILE A N 1 ATOM 3341 C CA . ILE A 1 412 ? 0.871 2.670 18.407 1.00 24.03 ? 412 ILE A CA 1 ATOM 3342 C C . ILE A 1 412 ? 1.585 3.862 19.020 1.00 23.92 ? 412 ILE A C 1 ATOM 3343 O O . ILE A 1 412 ? 1.442 4.118 20.216 1.00 24.21 ? 412 ILE A O 1 ATOM 3344 C CB . ILE A 1 412 ? -0.635 3.033 18.188 1.00 24.36 ? 412 ILE A CB 1 ATOM 3345 C CG1 . ILE A 1 412 ? -1.458 1.803 17.766 1.00 24.90 ? 412 ILE A CG1 1 ATOM 3346 C CG2 . ILE A 1 412 ? -0.816 4.217 17.202 1.00 24.31 ? 412 ILE A CG2 1 ATOM 3347 C CD1 . ILE A 1 412 ? -0.917 1.008 16.545 1.00 25.78 ? 412 ILE A CD1 1 ATOM 3348 N N . SER A 1 413 ? 2.371 4.578 18.218 1.00 23.44 ? 413 SER A N 1 ATOM 3349 C CA . SER A 1 413 ? 2.957 5.835 18.677 1.00 22.93 ? 413 SER A CA 1 ATOM 3350 C C . SER A 1 413 ? 2.948 6.886 17.580 1.00 22.98 ? 413 SER A C 1 ATOM 3351 O O . SER A 1 413 ? 2.455 6.628 16.488 1.00 23.10 ? 413 SER A O 1 ATOM 3352 C CB . SER A 1 413 ? 4.357 5.632 19.264 1.00 22.93 ? 413 SER A CB 1 ATOM 3353 O OG . SER A 1 413 ? 4.748 6.762 20.041 1.00 21.14 ? 413 SER A OG 1 ATOM 3354 N N . SER A 1 414 ? 3.488 8.068 17.873 1.00 23.16 ? 414 SER A N 1 ATOM 3355 C CA . SER A 1 414 ? 3.371 9.208 16.972 1.00 23.61 ? 414 SER A CA 1 ATOM 3356 C C . SER A 1 414 ? 4.703 9.712 16.394 1.00 23.92 ? 414 SER A C 1 ATOM 3357 O O . SER A 1 414 ? 4.698 10.493 15.419 1.00 23.94 ? 414 SER A O 1 ATOM 3358 C CB . SER A 1 414 ? 2.602 10.339 17.645 1.00 23.48 ? 414 SER A CB 1 ATOM 3359 O OG . SER A 1 414 ? 3.215 10.710 18.866 1.00 24.65 ? 414 SER A OG 1 ATOM 3360 N N . ASP A 1 415 ? 5.820 9.288 16.997 1.00 23.86 ? 415 ASP A N 1 ATOM 3361 C CA . ASP A 1 415 ? 7.145 9.436 16.386 1.00 24.35 ? 415 ASP A CA 1 ATOM 3362 C C . ASP A 1 415 ? 7.709 10.869 16.467 1.00 24.43 ? 415 ASP A C 1 ATOM 3363 O O . ASP A 1 415 ? 8.589 11.146 17.275 1.00 24.20 ? 415 ASP A O 1 ATOM 3364 C CB . ASP A 1 415 ? 7.087 8.925 14.933 1.00 24.69 ? 415 ASP A CB 1 ATOM 3365 C CG . ASP A 1 415 ? 8.438 8.521 14.378 1.00 25.51 ? 415 ASP A CG 1 ATOM 3366 O OD1 . ASP A 1 415 ? 9.442 8.629 15.108 1.00 27.08 ? 415 ASP A OD1 1 ATOM 3367 O OD2 . ASP A 1 415 ? 8.492 8.096 13.197 1.00 25.73 ? 415 ASP A OD2 1 ATOM 3368 N N . ASP A 1 416 ? 7.219 11.762 15.610 1.00 24.78 ? 416 ASP A N 1 ATOM 3369 C CA . ASP A 1 416 ? 7.565 13.188 15.662 1.00 25.13 ? 416 ASP A CA 1 ATOM 3370 C C . ASP A 1 416 ? 6.331 14.024 15.348 1.00 24.87 ? 416 ASP A C 1 ATOM 3371 O O . ASP A 1 416 ? 6.336 14.770 14.367 1.00 24.38 ? 416 ASP A O 1 ATOM 3372 C CB . ASP A 1 416 ? 8.658 13.548 14.653 1.00 25.41 ? 416 ASP A CB 1 ATOM 3373 C CG . ASP A 1 416 ? 9.865 12.663 14.759 1.00 27.16 ? 416 ASP A CG 1 ATOM 3374 O OD1 . ASP A 1 416 ? 10.833 13.047 15.451 1.00 28.54 ? 416 ASP A OD1 1 ATOM 3375 O OD2 . ASP A 1 416 ? 9.838 11.575 14.148 1.00 29.85 ? 416 ASP A OD2 1 ATOM 3376 N N . PRO A 1 417 ? 5.272 13.908 16.183 1.00 25.04 ? 417 PRO A N 1 ATOM 3377 C CA . PRO A 1 417 ? 3.976 14.527 15.867 1.00 25.09 ? 417 PRO A CA 1 ATOM 3378 C C . PRO A 1 417 ? 4.097 15.996 15.455 1.00 25.45 ? 417 PRO A C 1 ATOM 3379 O O . PRO A 1 417 ? 3.499 16.393 14.458 1.00 25.90 ? 417 PRO A O 1 ATOM 3380 C CB . PRO A 1 417 ? 3.180 14.383 17.173 1.00 25.06 ? 417 PRO A CB 1 ATOM 3381 C CG . PRO A 1 417 ? 4.209 14.006 18.233 1.00 24.79 ? 417 PRO A CG 1 ATOM 3382 C CD . PRO A 1 417 ? 5.263 13.264 17.511 1.00 24.62 ? 417 PRO A CD 1 ATOM 3383 N N . ALA A 1 418 ? 4.888 16.772 16.195 1.00 25.63 ? 418 ALA A N 1 ATOM 3384 C CA . ALA A 1 418 ? 5.123 18.190 15.916 1.00 25.94 ? 418 ALA A CA 1 ATOM 3385 C C . ALA A 1 418 ? 5.565 18.511 14.475 1.00 26.29 ? 418 ALA A C 1 ATOM 3386 O O . ALA A 1 418 ? 5.187 19.545 13.932 1.00 26.32 ? 418 ALA A O 1 ATOM 3387 C CB . ALA A 1 418 ? 6.123 18.759 16.909 1.00 25.74 ? 418 ALA A CB 1 ATOM 3388 N N . MET A 1 419 ? 6.371 17.642 13.869 1.00 26.76 ? 419 MET A N 1 ATOM 3389 C CA . MET A 1 419 ? 6.868 17.871 12.509 1.00 27.44 ? 419 MET A CA 1 ATOM 3390 C C . MET A 1 419 ? 5.800 17.648 11.453 1.00 26.59 ? 419 MET A C 1 ATOM 3391 O O . MET A 1 419 ? 5.898 18.170 10.340 1.00 26.13 ? 419 MET A O 1 ATOM 3392 C CB . MET A 1 419 ? 8.083 16.989 12.198 1.00 28.22 ? 419 MET A CB 1 ATOM 3393 C CG . MET A 1 419 ? 9.385 17.761 12.050 1.00 32.05 ? 419 MET A CG 1 ATOM 3394 S SD . MET A 1 419 ? 10.549 17.610 13.413 1.00 40.47 ? 419 MET A SD 1 ATOM 3395 C CE . MET A 1 419 ? 9.460 17.318 14.798 1.00 40.19 ? 419 MET A CE 1 ATOM 3396 N N . PHE A 1 420 ? 4.785 16.869 11.818 1.00 26.09 ? 420 PHE A N 1 ATOM 3397 C CA . PHE A 1 420 ? 3.698 16.513 10.906 1.00 25.71 ? 420 PHE A CA 1 ATOM 3398 C C . PHE A 1 420 ? 2.455 17.358 11.140 1.00 25.81 ? 420 PHE A C 1 ATOM 3399 O O . PHE A 1 420 ? 1.482 17.246 10.402 1.00 26.06 ? 420 PHE A O 1 ATOM 3400 C CB . PHE A 1 420 ? 3.349 15.024 11.035 1.00 25.27 ? 420 PHE A CB 1 ATOM 3401 C CG . PHE A 1 420 ? 4.551 14.120 11.088 1.00 24.31 ? 420 PHE A CG 1 ATOM 3402 C CD1 . PHE A 1 420 ? 5.647 14.334 10.248 1.00 23.79 ? 420 PHE A CD1 1 ATOM 3403 C CD2 . PHE A 1 420 ? 4.587 13.053 11.968 1.00 21.68 ? 420 PHE A CD2 1 ATOM 3404 C CE1 . PHE A 1 420 ? 6.750 13.509 10.304 1.00 22.95 ? 420 PHE A CE1 1 ATOM 3405 C CE2 . PHE A 1 420 ? 5.677 12.227 12.023 1.00 21.57 ? 420 PHE A CE2 1 ATOM 3406 C CZ . PHE A 1 420 ? 6.760 12.449 11.189 1.00 22.73 ? 420 PHE A CZ 1 ATOM 3407 N N . GLY A 1 421 ? 2.494 18.204 12.164 1.00 25.80 ? 421 GLY A N 1 ATOM 3408 C CA . GLY A 1 421 ? 1.336 19.001 12.533 1.00 25.97 ? 421 GLY A CA 1 ATOM 3409 C C . GLY A 1 421 ? 0.359 18.239 13.400 1.00 26.17 ? 421 GLY A C 1 ATOM 3410 O O . GLY A 1 421 ? -0.801 18.614 13.506 1.00 26.20 ? 421 GLY A O 1 ATOM 3411 N N . ALA A 1 422 ? 0.827 17.164 14.023 1.00 26.51 ? 422 ALA A N 1 ATOM 3412 C CA . ALA A 1 422 ? 0.017 16.410 14.977 1.00 26.86 ? 422 ALA A CA 1 ATOM 3413 C C . ALA A 1 422 ? 0.379 16.791 16.420 1.00 27.31 ? 422 ALA A C 1 ATOM 3414 O O . ALA A 1 422 ? 1.292 17.583 16.666 1.00 26.90 ? 422 ALA A O 1 ATOM 3415 C CB . ALA A 1 422 ? 0.191 14.917 14.754 1.00 26.58 ? 422 ALA A CB 1 ATOM 3416 N N . LYS A 1 423 ? -0.348 16.209 17.364 1.00 27.85 ? 423 LYS A N 1 ATOM 3417 C CA . LYS A 1 423 ? -0.151 16.479 18.765 1.00 28.54 ? 423 LYS A CA 1 ATOM 3418 C C . LYS A 1 423 ? -0.441 15.193 19.554 1.00 28.18 ? 423 LYS A C 1 ATOM 3419 O O . LYS A 1 423 ? -1.478 14.556 19.357 1.00 28.16 ? 423 LYS A O 1 ATOM 3420 C CB . LYS A 1 423 ? -1.075 17.631 19.196 1.00 28.93 ? 423 LYS A CB 1 ATOM 3421 C CG . LYS A 1 423 ? -0.558 18.415 20.399 1.00 32.06 ? 423 LYS A CG 1 ATOM 3422 C CD . LYS A 1 423 ? -1.521 19.495 20.926 1.00 36.97 ? 423 LYS A CD 1 ATOM 3423 C CE . LYS A 1 423 ? -2.988 19.067 20.911 1.00 39.85 ? 423 LYS A CE 1 ATOM 3424 N NZ . LYS A 1 423 ? -3.884 20.128 21.492 1.00 42.52 ? 423 LYS A NZ 1 ATOM 3425 N N . GLY A 1 424 ? 0.485 14.807 20.428 1.00 27.99 ? 424 GLY A N 1 ATOM 3426 C CA . GLY A 1 424 ? 0.293 13.638 21.289 1.00 27.65 ? 424 GLY A CA 1 ATOM 3427 C C . GLY A 1 424 ? 0.131 12.340 20.515 1.00 27.59 ? 424 GLY A C 1 ATOM 3428 O O . GLY A 1 424 ? 0.959 12.011 19.663 1.00 27.70 ? 424 GLY A O 1 ATOM 3429 N N . LEU A 1 425 ? -0.953 11.618 20.786 1.00 27.33 ? 425 LEU A N 1 ATOM 3430 C CA . LEU A 1 425 ? -1.108 10.254 20.291 1.00 26.88 ? 425 LEU A CA 1 ATOM 3431 C C . LEU A 1 425 ? -2.439 9.980 19.572 1.00 26.75 ? 425 LEU A C 1 ATOM 3432 O O . LEU A 1 425 ? -2.583 8.942 18.914 1.00 27.16 ? 425 LEU A O 1 ATOM 3433 C CB . LEU A 1 425 ? -0.937 9.290 21.463 1.00 26.64 ? 425 LEU A CB 1 ATOM 3434 C CG . LEU A 1 425 ? 0.028 8.104 21.378 1.00 26.99 ? 425 LEU A CG 1 ATOM 3435 C CD1 . LEU A 1 425 ? 1.420 8.476 20.829 1.00 25.55 ? 425 LEU A CD1 1 ATOM 3436 C CD2 . LEU A 1 425 ? 0.150 7.459 22.749 1.00 25.41 ? 425 LEU A CD2 1 ATOM 3437 N N . SER A 1 426 ? -3.391 10.905 19.681 1.00 26.16 ? 426 SER A N 1 ATOM 3438 C CA . SER A 1 426 ? -4.776 10.667 19.230 1.00 25.83 ? 426 SER A CA 1 ATOM 3439 C C . SER A 1 426 ? -4.951 10.609 17.716 1.00 25.40 ? 426 SER A C 1 ATOM 3440 O O . SER A 1 426 ? -5.773 9.843 17.209 1.00 24.97 ? 426 SER A O 1 ATOM 3441 C CB . SER A 1 426 ? -5.743 11.708 19.813 1.00 25.84 ? 426 SER A CB 1 ATOM 3442 O OG . SER A 1 426 ? -5.836 11.604 21.219 1.00 25.96 ? 426 SER A OG 1 ATOM 3443 N N . TYR A 1 427 ? -4.197 11.443 17.008 1.00 25.35 ? 427 TYR A N 1 ATOM 3444 C CA . TYR A 1 427 ? -4.207 11.434 15.550 1.00 25.41 ? 427 TYR A CA 1 ATOM 3445 C C . TYR A 1 427 ? -3.777 10.065 14.998 1.00 25.01 ? 427 TYR A C 1 ATOM 3446 O O . TYR A 1 427 ? -4.410 9.526 14.093 1.00 24.73 ? 427 TYR A O 1 ATOM 3447 C CB . TYR A 1 427 ? -3.322 12.564 14.999 1.00 25.54 ? 427 TYR A CB 1 ATOM 3448 C CG . TYR A 1 427 ? -3.828 13.955 15.313 1.00 26.45 ? 427 TYR A CG 1 ATOM 3449 C CD1 . TYR A 1 427 ? -3.367 14.646 16.433 1.00 27.41 ? 427 TYR A CD1 1 ATOM 3450 C CD2 . TYR A 1 427 ? -4.768 14.580 14.489 1.00 26.71 ? 427 TYR A CD2 1 ATOM 3451 C CE1 . TYR A 1 427 ? -3.827 15.925 16.731 1.00 27.43 ? 427 TYR A CE1 1 ATOM 3452 C CE2 . TYR A 1 427 ? -5.235 15.853 14.774 1.00 28.27 ? 427 TYR A CE2 1 ATOM 3453 C CZ . TYR A 1 427 ? -4.764 16.520 15.900 1.00 28.37 ? 427 TYR A CZ 1 ATOM 3454 O OH . TYR A 1 427 ? -5.223 17.780 16.190 1.00 28.33 ? 427 TYR A OH 1 ATOM 3455 N N . ASP A 1 428 ? -2.716 9.504 15.562 1.00 25.10 ? 428 ASP A N 1 ATOM 3456 C CA . ASP A 1 428 ? -2.229 8.192 15.133 1.00 25.57 ? 428 ASP A CA 1 ATOM 3457 C C . ASP A 1 428 ? -3.184 7.052 15.507 1.00 24.91 ? 428 ASP A C 1 ATOM 3458 O O . ASP A 1 428 ? -3.341 6.105 14.732 1.00 24.85 ? 428 ASP A O 1 ATOM 3459 C CB . ASP A 1 428 ? -0.796 7.944 15.620 1.00 25.98 ? 428 ASP A CB 1 ATOM 3460 C CG . ASP A 1 428 ? 0.224 8.803 14.873 1.00 28.47 ? 428 ASP A CG 1 ATOM 3461 O OD1 . ASP A 1 428 ? 0.853 8.280 13.925 1.00 31.28 ? 428 ASP A OD1 1 ATOM 3462 O OD2 . ASP A 1 428 ? 0.364 10.013 15.197 1.00 29.69 ? 428 ASP A OD2 1 ATOM 3463 N N . PHE A 1 429 ? -3.837 7.165 16.665 1.00 24.27 ? 429 PHE A N 1 ATOM 3464 C CA . PHE A 1 429 ? -4.911 6.240 17.052 1.00 23.97 ? 429 PHE A CA 1 ATOM 3465 C C . PHE A 1 429 ? -6.102 6.337 16.097 1.00 24.03 ? 429 PHE A C 1 ATOM 3466 O O . PHE A 1 429 ? -6.756 5.329 15.810 1.00 24.28 ? 429 PHE A O 1 ATOM 3467 C CB . PHE A 1 429 ? -5.366 6.475 18.503 1.00 23.67 ? 429 PHE A CB 1 ATOM 3468 C CG . PHE A 1 429 ? -4.719 5.558 19.504 1.00 23.20 ? 429 PHE A CG 1 ATOM 3469 C CD1 . PHE A 1 429 ? -3.453 5.838 20.015 1.00 23.16 ? 429 PHE A CD1 1 ATOM 3470 C CD2 . PHE A 1 429 ? -5.373 4.405 19.935 1.00 22.59 ? 429 PHE A CD2 1 ATOM 3471 C CE1 . PHE A 1 429 ? -2.846 4.987 20.949 1.00 22.30 ? 429 PHE A CE1 1 ATOM 3472 C CE2 . PHE A 1 429 ? -4.777 3.549 20.856 1.00 22.54 ? 429 PHE A CE2 1 ATOM 3473 C CZ . PHE A 1 429 ? -3.508 3.846 21.372 1.00 22.05 ? 429 PHE A CZ 1 ATOM 3474 N N . TYR A 1 430 ? -6.383 7.541 15.600 1.00 23.77 ? 430 TYR A N 1 ATOM 3475 C CA . TYR A 1 430 ? -7.436 7.713 14.602 1.00 23.77 ? 430 TYR A CA 1 ATOM 3476 C C . TYR A 1 430 ? -7.121 6.941 13.324 1.00 23.59 ? 430 TYR A C 1 ATOM 3477 O O . TYR A 1 430 ? -7.975 6.230 12.792 1.00 23.74 ? 430 TYR A O 1 ATOM 3478 C CB . TYR A 1 430 ? -7.673 9.195 14.285 1.00 23.78 ? 430 TYR A CB 1 ATOM 3479 C CG . TYR A 1 430 ? -8.688 9.395 13.185 1.00 24.46 ? 430 TYR A CG 1 ATOM 3480 C CD1 . TYR A 1 430 ? -8.292 9.440 11.837 1.00 24.10 ? 430 TYR A CD1 1 ATOM 3481 C CD2 . TYR A 1 430 ? -10.053 9.521 13.479 1.00 25.04 ? 430 TYR A CD2 1 ATOM 3482 C CE1 . TYR A 1 430 ? -9.227 9.605 10.820 1.00 23.85 ? 430 TYR A CE1 1 ATOM 3483 C CE2 . TYR A 1 430 ? -10.992 9.694 12.463 1.00 24.69 ? 430 TYR A CE2 1 ATOM 3484 C CZ . TYR A 1 430 ? -10.563 9.732 11.139 1.00 24.43 ? 430 TYR A CZ 1 ATOM 3485 O OH . TYR A 1 430 ? -11.472 9.895 10.126 1.00 26.70 ? 430 TYR A OH 1 ATOM 3486 N N . GLU A 1 431 ? -5.888 7.094 12.841 1.00 23.15 ? 431 GLU A N 1 ATOM 3487 C CA . GLU A 1 431 ? -5.459 6.493 11.586 1.00 22.30 ? 431 GLU A CA 1 ATOM 3488 C C . GLU A 1 431 ? -5.518 4.976 11.667 1.00 22.18 ? 431 GLU A C 1 ATOM 3489 O O . GLU A 1 431 ? -6.008 4.313 10.745 1.00 21.78 ? 431 GLU A O 1 ATOM 3490 C CB . GLU A 1 431 ? -4.052 6.968 11.222 1.00 22.13 ? 431 GLU A CB 1 ATOM 3491 C CG . GLU A 1 431 ? -3.922 8.463 11.023 1.00 21.68 ? 431 GLU A CG 1 ATOM 3492 C CD . GLU A 1 431 ? -4.503 8.965 9.699 1.00 22.08 ? 431 GLU A CD 1 ATOM 3493 O OE1 . GLU A 1 431 ? -5.558 8.458 9.256 1.00 21.16 ? 431 GLU A OE1 1 ATOM 3494 O OE2 . GLU A 1 431 ? -3.901 9.894 9.105 1.00 22.35 ? 431 GLU A OE2 1 ATOM 3495 N N . VAL A 1 432 ? -5.040 4.438 12.789 1.00 21.87 ? 432 VAL A N 1 ATOM 3496 C CA . VAL A 1 432 ? -5.066 3.001 13.024 1.00 21.66 ? 432 VAL A CA 1 ATOM 3497 C C . VAL A 1 432 ? -6.501 2.495 13.065 1.00 22.00 ? 432 VAL A C 1 ATOM 3498 O O . VAL A 1 432 ? -6.854 1.560 12.349 1.00 21.79 ? 432 VAL A O 1 ATOM 3499 C CB . VAL A 1 432 ? -4.328 2.615 14.327 1.00 21.42 ? 432 VAL A CB 1 ATOM 3500 C CG1 . VAL A 1 432 ? -4.599 1.161 14.690 1.00 21.01 ? 432 VAL A CG1 1 ATOM 3501 C CG2 . VAL A 1 432 ? -2.827 2.866 14.192 1.00 20.98 ? 432 VAL A CG2 1 ATOM 3502 N N . PHE A 1 433 ? -7.321 3.139 13.891 1.00 22.52 ? 433 PHE A N 1 ATOM 3503 C CA . PHE A 1 433 ? -8.687 2.696 14.162 1.00 22.95 ? 433 PHE A CA 1 ATOM 3504 C C . PHE A 1 433 ? -9.619 2.834 12.970 1.00 23.50 ? 433 PHE A C 1 ATOM 3505 O O . PHE A 1 433 ? -10.490 1.980 12.765 1.00 23.77 ? 433 PHE A O 1 ATOM 3506 C CB . PHE A 1 433 ? -9.250 3.478 15.353 1.00 23.03 ? 433 PHE A CB 1 ATOM 3507 C CG . PHE A 1 433 ? -10.606 3.014 15.816 1.00 23.18 ? 433 PHE A CG 1 ATOM 3508 C CD1 . PHE A 1 433 ? -10.775 1.748 16.383 1.00 23.56 ? 433 PHE A CD1 1 ATOM 3509 C CD2 . PHE A 1 433 ? -11.708 3.857 15.715 1.00 22.87 ? 433 PHE A CD2 1 ATOM 3510 C CE1 . PHE A 1 433 ? -12.034 1.323 16.822 1.00 24.25 ? 433 PHE A CE1 1 ATOM 3511 C CE2 . PHE A 1 433 ? -12.961 3.448 16.154 1.00 23.54 ? 433 PHE A CE2 1 ATOM 3512 C CZ . PHE A 1 433 ? -13.129 2.183 16.707 1.00 24.10 ? 433 PHE A CZ 1 ATOM 3513 N N . MET A 1 434 ? -9.456 3.904 12.195 1.00 23.96 ? 434 MET A N 1 ATOM 3514 C CA . MET A 1 434 ? -10.332 4.146 11.048 1.00 24.80 ? 434 MET A CA 1 ATOM 3515 C C . MET A 1 434 ? -9.743 3.630 9.721 1.00 24.74 ? 434 MET A C 1 ATOM 3516 O O . MET A 1 434 ? -10.473 3.127 8.863 1.00 24.84 ? 434 MET A O 1 ATOM 3517 C CB . MET A 1 434 ? -10.696 5.634 10.942 1.00 24.97 ? 434 MET A CB 1 ATOM 3518 C CG . MET A 1 434 ? -11.499 6.176 12.127 1.00 26.92 ? 434 MET A CG 1 ATOM 3519 S SD . MET A 1 434 ? -13.202 5.570 12.194 1.00 30.06 ? 434 MET A SD 1 ATOM 3520 C CE . MET A 1 434 ? -13.926 6.496 10.844 1.00 28.88 ? 434 MET A CE 1 ATOM 3521 N N . GLY A 1 435 ? -8.429 3.763 9.557 1.00 24.60 ? 435 GLY A N 1 ATOM 3522 C CA . GLY A 1 435 ? -7.782 3.442 8.290 1.00 24.58 ? 435 GLY A CA 1 ATOM 3523 C C . GLY A 1 435 ? -7.193 2.051 8.222 1.00 24.39 ? 435 GLY A C 1 ATOM 3524 O O . GLY A 1 435 ? -7.601 1.239 7.403 1.00 24.99 ? 435 GLY A O 1 ATOM 3525 N N . ILE A 1 436 ? -6.237 1.771 9.094 1.00 23.89 ? 436 ILE A N 1 ATOM 3526 C CA . ILE A 1 436 ? -5.501 0.516 9.046 1.00 23.32 ? 436 ILE A CA 1 ATOM 3527 C C . ILE A 1 436 ? -6.331 -0.674 9.557 1.00 23.42 ? 436 ILE A C 1 ATOM 3528 O O . ILE A 1 436 ? -6.321 -1.749 8.953 1.00 23.40 ? 436 ILE A O 1 ATOM 3529 C CB . ILE A 1 436 ? -4.167 0.653 9.810 1.00 23.40 ? 436 ILE A CB 1 ATOM 3530 C CG1 . ILE A 1 436 ? -3.376 1.856 9.264 1.00 22.41 ? 436 ILE A CG1 1 ATOM 3531 C CG2 . ILE A 1 436 ? -3.353 -0.642 9.745 1.00 22.75 ? 436 ILE A CG2 1 ATOM 3532 C CD1 . ILE A 1 436 ? -2.198 2.268 10.118 1.00 20.64 ? 436 ILE A CD1 1 ATOM 3533 N N . GLY A 1 437 ? -7.058 -0.470 10.650 1.00 23.45 ? 437 GLY A N 1 ATOM 3534 C CA . GLY A 1 437 ? -7.861 -1.521 11.263 1.00 23.71 ? 437 GLY A CA 1 ATOM 3535 C C . GLY A 1 437 ? -9.116 -1.933 10.520 1.00 24.01 ? 437 GLY A C 1 ATOM 3536 O O . GLY A 1 437 ? -9.652 -3.009 10.768 1.00 24.11 ? 437 GLY A O 1 ATOM 3537 N N . GLY A 1 438 ? -9.596 -1.087 9.615 1.00 24.74 ? 438 GLY A N 1 ATOM 3538 C CA . GLY A 1 438 ? -10.811 -1.386 8.851 1.00 25.48 ? 438 GLY A CA 1 ATOM 3539 C C . GLY A 1 438 ? -12.069 -1.176 9.670 1.00 26.06 ? 438 GLY A C 1 ATOM 3540 O O . GLY A 1 438 ? -12.001 -0.801 10.843 1.00 26.20 ? 438 GLY A O 1 ATOM 3541 N N . MET A 1 439 ? -13.220 -1.436 9.060 1.00 26.70 ? 439 MET A N 1 ATOM 3542 C CA . MET A 1 439 ? -14.508 -1.115 9.677 1.00 27.61 ? 439 MET A CA 1 ATOM 3543 C C . MET A 1 439 ? -14.844 -1.945 10.923 1.00 27.76 ? 439 MET A C 1 ATOM 3544 O O . MET A 1 439 ? -15.614 -1.510 11.769 1.00 27.74 ? 439 MET A O 1 ATOM 3545 C CB . MET A 1 439 ? -15.640 -1.214 8.646 1.00 27.91 ? 439 MET A CB 1 ATOM 3546 C CG . MET A 1 439 ? -16.988 -0.730 9.162 1.00 29.80 ? 439 MET A CG 1 ATOM 3547 S SD . MET A 1 439 ? -18.317 -0.912 7.960 1.00 35.56 ? 439 MET A SD 1 ATOM 3548 C CE . MET A 1 439 ? -18.304 0.699 7.173 1.00 31.11 ? 439 MET A CE 1 ATOM 3549 N N . LYS A 1 440 ? -14.257 -3.130 11.036 1.00 28.24 ? 440 LYS A N 1 ATOM 3550 C CA . LYS A 1 440 ? -14.555 -4.038 12.134 1.00 28.54 ? 440 LYS A CA 1 ATOM 3551 C C . LYS A 1 440 ? -13.652 -3.844 13.360 1.00 28.60 ? 440 LYS A C 1 ATOM 3552 O O . LYS A 1 440 ? -13.825 -4.525 14.366 1.00 29.13 ? 440 LYS A O 1 ATOM 3553 C CB . LYS A 1 440 ? -14.462 -5.478 11.645 1.00 28.78 ? 440 LYS A CB 1 ATOM 3554 C CG . LYS A 1 440 ? -15.492 -5.862 10.607 1.00 29.84 ? 440 LYS A CG 1 ATOM 3555 C CD . LYS A 1 440 ? -16.625 -6.612 11.241 1.00 32.01 ? 440 LYS A CD 1 ATOM 3556 C CE . LYS A 1 440 ? -17.149 -7.666 10.297 1.00 33.89 ? 440 LYS A CE 1 ATOM 3557 N NZ . LYS A 1 440 ? -18.240 -7.082 9.495 1.00 35.08 ? 440 LYS A NZ 1 ATOM 3558 N N . ALA A 1 441 ? -12.682 -2.940 13.278 1.00 28.35 ? 441 ALA A N 1 ATOM 3559 C CA . ALA A 1 441 ? -11.901 -2.570 14.455 1.00 28.30 ? 441 ALA A CA 1 ATOM 3560 C C . ALA A 1 441 ? -12.833 -1.861 15.447 1.00 28.29 ? 441 ALA A C 1 ATOM 3561 O O . ALA A 1 441 ? -13.505 -0.894 15.090 1.00 27.95 ? 441 ALA A O 1 ATOM 3562 C CB . ALA A 1 441 ? -10.724 -1.669 14.069 1.00 27.92 ? 441 ALA A CB 1 ATOM 3563 N N . ASP A 1 442 ? -12.868 -2.353 16.685 1.00 28.36 ? 442 ASP A N 1 ATOM 3564 C CA . ASP A 1 442 ? -13.815 -1.868 17.691 1.00 28.48 ? 442 ASP A CA 1 ATOM 3565 C C . ASP A 1 442 ? -13.137 -1.425 19.012 1.00 28.47 ? 442 ASP A C 1 ATOM 3566 O O . ASP A 1 442 ? -11.931 -1.179 19.052 1.00 28.49 ? 442 ASP A O 1 ATOM 3567 C CB . ASP A 1 442 ? -14.886 -2.941 17.939 1.00 28.58 ? 442 ASP A CB 1 ATOM 3568 C CG . ASP A 1 442 ? -14.312 -4.244 18.531 1.00 29.23 ? 442 ASP A CG 1 ATOM 3569 O OD1 . ASP A 1 442 ? -13.111 -4.300 18.885 1.00 30.58 ? 442 ASP A OD1 1 ATOM 3570 O OD2 . ASP A 1 442 ? -15.074 -5.227 18.646 1.00 29.90 ? 442 ASP A OD2 1 ATOM 3571 N N . LEU A 1 443 ? -13.920 -1.333 20.085 1.00 28.31 ? 443 LEU A N 1 ATOM 3572 C CA . LEU A 1 443 ? -13.418 -0.912 21.388 1.00 28.09 ? 443 LEU A CA 1 ATOM 3573 C C . LEU A 1 443 ? -12.393 -1.895 21.947 1.00 27.90 ? 443 LEU A C 1 ATOM 3574 O O . LEU A 1 443 ? -11.505 -1.507 22.714 1.00 27.78 ? 443 LEU A O 1 ATOM 3575 C CB . LEU A 1 443 ? -14.571 -0.718 22.377 1.00 28.14 ? 443 LEU A CB 1 ATOM 3576 C CG . LEU A 1 443 ? -14.297 -0.026 23.727 1.00 28.71 ? 443 LEU A CG 1 ATOM 3577 C CD1 . LEU A 1 443 ? -14.047 1.475 23.575 1.00 28.37 ? 443 LEU A CD1 1 ATOM 3578 C CD2 . LEU A 1 443 ? -15.435 -0.273 24.717 1.00 27.92 ? 443 LEU A CD2 1 ATOM 3579 N N . ARG A 1 444 ? -12.513 -3.159 21.553 1.00 27.60 ? 444 ARG A N 1 ATOM 3580 C CA . ARG A 1 444 ? -11.560 -4.194 21.955 1.00 27.59 ? 444 ARG A CA 1 ATOM 3581 C C . ARG A 1 444 ? -10.173 -3.936 21.385 1.00 27.35 ? 444 ARG A C 1 ATOM 3582 O O . ARG A 1 444 ? -9.171 -4.061 22.098 1.00 27.16 ? 444 ARG A O 1 ATOM 3583 C CB . ARG A 1 444 ? -12.042 -5.576 21.517 1.00 27.92 ? 444 ARG A CB 1 ATOM 3584 C CG . ARG A 1 444 ? -13.230 -6.094 22.283 1.00 27.96 ? 444 ARG A CG 1 ATOM 3585 C CD . ARG A 1 444 ? -13.654 -7.452 21.757 1.00 28.92 ? 444 ARG A CD 1 ATOM 3586 N NE . ARG A 1 444 ? -14.893 -7.893 22.397 1.00 30.69 ? 444 ARG A NE 1 ATOM 3587 C CZ . ARG A 1 444 ? -16.106 -7.463 22.053 1.00 30.89 ? 444 ARG A CZ 1 ATOM 3588 N NH1 . ARG A 1 444 ? -16.241 -6.586 21.067 1.00 31.22 ? 444 ARG A NH1 1 ATOM 3589 N NH2 . ARG A 1 444 ? -17.184 -7.904 22.690 1.00 30.25 ? 444 ARG A NH2 1 ATOM 3590 N N . THR A 1 445 ? -10.133 -3.592 20.096 1.00 27.15 ? 445 THR A N 1 ATOM 3591 C CA . THR A 1 445 ? -8.904 -3.189 19.406 1.00 26.91 ? 445 THR A CA 1 ATOM 3592 C C . THR A 1 445 ? -8.199 -2.069 20.173 1.00 26.69 ? 445 THR A C 1 ATOM 3593 O O . THR A 1 445 ? -7.003 -2.155 20.469 1.00 26.53 ? 445 THR A O 1 ATOM 3594 C CB . THR A 1 445 ? -9.207 -2.678 17.965 1.00 27.08 ? 445 THR A CB 1 ATOM 3595 O OG1 . THR A 1 445 ? -10.055 -3.607 17.277 1.00 27.26 ? 445 THR A OG1 1 ATOM 3596 C CG2 . THR A 1 445 ? -7.916 -2.443 17.172 1.00 26.20 ? 445 THR A CG2 1 ATOM 3597 N N . LEU A 1 446 ? -8.958 -1.020 20.484 1.00 26.39 ? 446 LEU A N 1 ATOM 3598 C CA . LEU A 1 446 ? -8.432 0.138 21.190 1.00 26.33 ? 446 LEU A CA 1 ATOM 3599 C C . LEU A 1 446 ? -7.880 -0.255 22.545 1.00 26.62 ? 446 LEU A C 1 ATOM 3600 O O . LEU A 1 446 ? -6.752 0.094 22.883 1.00 26.66 ? 446 LEU A O 1 ATOM 3601 C CB . LEU A 1 446 ? -9.512 1.210 21.343 1.00 25.89 ? 446 LEU A CB 1 ATOM 3602 C CG . LEU A 1 446 ? -9.994 1.858 20.035 1.00 25.61 ? 446 LEU A CG 1 ATOM 3603 C CD1 . LEU A 1 446 ? -11.258 2.676 20.254 1.00 23.01 ? 446 LEU A CD1 1 ATOM 3604 C CD2 . LEU A 1 446 ? -8.884 2.700 19.376 1.00 24.97 ? 446 LEU A CD2 1 ATOM 3605 N N . LYS A 1 447 ? -8.685 -1.000 23.299 1.00 27.14 ? 447 LYS A N 1 ATOM 3606 C CA . LYS A 1 447 ? -8.336 -1.422 24.642 1.00 27.46 ? 447 LYS A CA 1 ATOM 3607 C C . LYS A 1 447 ? -7.062 -2.268 24.643 1.00 27.22 ? 447 LYS A C 1 ATOM 3608 O O . LYS A 1 447 ? -6.165 -2.036 25.443 1.00 27.22 ? 447 LYS A O 1 ATOM 3609 C CB . LYS A 1 447 ? -9.502 -2.183 25.273 1.00 27.73 ? 447 LYS A CB 1 ATOM 3610 C CG . LYS A 1 447 ? -9.420 -2.267 26.781 1.00 28.84 ? 447 LYS A CG 1 ATOM 3611 C CD . LYS A 1 447 ? -10.519 -3.133 27.352 1.00 30.76 ? 447 LYS A CD 1 ATOM 3612 C CE . LYS A 1 447 ? -10.461 -3.111 28.862 1.00 31.95 ? 447 LYS A CE 1 ATOM 3613 N NZ . LYS A 1 447 ? -11.584 -3.848 29.456 1.00 32.92 ? 447 LYS A NZ 1 ATOM 3614 N N . GLN A 1 448 ? -6.992 -3.232 23.733 1.00 27.34 ? 448 GLN A N 1 ATOM 3615 C CA . GLN A 1 448 ? -5.801 -4.058 23.559 1.00 27.42 ? 448 GLN A CA 1 ATOM 3616 C C . GLN A 1 448 ? -4.554 -3.222 23.279 1.00 27.24 ? 448 GLN A C 1 ATOM 3617 O O . GLN A 1 448 ? -3.511 -3.456 23.890 1.00 27.30 ? 448 GLN A O 1 ATOM 3618 C CB . GLN A 1 448 ? -6.017 -5.082 22.444 1.00 27.63 ? 448 GLN A CB 1 ATOM 3619 C CG . GLN A 1 448 ? -4.929 -6.134 22.344 1.00 29.05 ? 448 GLN A CG 1 ATOM 3620 C CD . GLN A 1 448 ? -4.905 -7.055 23.548 1.00 31.09 ? 448 GLN A CD 1 ATOM 3621 O OE1 . GLN A 1 448 ? -5.761 -7.925 23.696 1.00 33.38 ? 448 GLN A OE1 1 ATOM 3622 N NE2 . GLN A 1 448 ? -3.921 -6.868 24.415 1.00 30.53 ? 448 GLN A NE2 1 ATOM 3623 N N . LEU A 1 449 ? -4.668 -2.240 22.381 1.00 26.85 ? 449 LEU A N 1 ATOM 3624 C CA . LEU A 1 449 ? -3.544 -1.358 22.042 1.00 26.56 ? 449 LEU A CA 1 ATOM 3625 C C . LEU A 1 449 ? -3.097 -0.480 23.213 1.00 26.61 ? 449 LEU A C 1 ATOM 3626 O O . LEU A 1 449 ? -1.896 -0.216 23.378 1.00 26.58 ? 449 LEU A O 1 ATOM 3627 C CB . LEU A 1 449 ? -3.870 -0.490 20.825 1.00 26.63 ? 449 LEU A CB 1 ATOM 3628 C CG . LEU A 1 449 ? -3.879 -1.164 19.451 1.00 26.26 ? 449 LEU A CG 1 ATOM 3629 C CD1 . LEU A 1 449 ? -4.585 -0.291 18.413 1.00 25.89 ? 449 LEU A CD1 1 ATOM 3630 C CD2 . LEU A 1 449 ? -2.471 -1.544 18.998 1.00 25.84 ? 449 LEU A CD2 1 ATOM 3631 N N . ALA A 1 450 ? -4.057 -0.032 24.022 1.00 26.36 ? 450 ALA A N 1 ATOM 3632 C CA . ALA A 1 450 ? -3.750 0.713 25.248 1.00 26.42 ? 450 ALA A CA 1 ATOM 3633 C C . ALA A 1 450 ? -2.979 -0.155 26.254 1.00 26.49 ? 450 ALA A C 1 ATOM 3634 O O . ALA A 1 450 ? -1.970 0.273 26.814 1.00 26.27 ? 450 ALA A O 1 ATOM 3635 C CB . ALA A 1 450 ? -5.027 1.268 25.877 1.00 26.10 ? 450 ALA A CB 1 ATOM 3636 N N . MET A 1 451 ? -3.450 -1.382 26.462 1.00 26.67 ? 451 MET A N 1 ATOM 3637 C CA . MET A 1 451 ? -2.826 -2.283 27.424 1.00 26.99 ? 451 MET A CA 1 ATOM 3638 C C . MET A 1 451 ? -1.469 -2.775 26.937 1.00 26.86 ? 451 MET A C 1 ATOM 3639 O O . MET A 1 451 ? -0.526 -2.874 27.721 1.00 26.94 ? 451 MET A O 1 ATOM 3640 C CB . MET A 1 451 ? -3.759 -3.450 27.756 1.00 27.08 ? 451 MET A CB 1 ATOM 3641 C CG . MET A 1 451 ? -5.042 -3.002 28.458 1.00 28.54 ? 451 MET A CG 1 ATOM 3642 S SD . MET A 1 451 ? -6.145 -4.326 29.010 1.00 30.30 ? 451 MET A SD 1 ATOM 3643 C CE . MET A 1 451 ? -6.339 -5.323 27.532 1.00 28.94 ? 451 MET A CE 1 ATOM 3644 N N . ASN A 1 452 ? -1.371 -3.069 25.643 1.00 26.96 ? 452 ASN A N 1 ATOM 3645 C CA . ASN A 1 452 ? -0.091 -3.428 25.025 1.00 27.08 ? 452 ASN A CA 1 ATOM 3646 C C . ASN A 1 452 ? 1.013 -2.431 25.331 1.00 26.94 ? 452 ASN A C 1 ATOM 3647 O O . ASN A 1 452 ? 2.155 -2.820 25.553 1.00 26.94 ? 452 ASN A O 1 ATOM 3648 C CB . ASN A 1 452 ? -0.232 -3.576 23.508 1.00 26.90 ? 452 ASN A CB 1 ATOM 3649 C CG . ASN A 1 452 ? -0.814 -4.914 23.100 1.00 26.95 ? 452 ASN A CG 1 ATOM 3650 O OD1 . ASN A 1 452 ? -1.120 -5.759 23.945 1.00 26.31 ? 452 ASN A OD1 1 ATOM 3651 N ND2 . ASN A 1 452 ? -0.970 -5.116 21.790 1.00 26.85 ? 452 ASN A ND2 1 ATOM 3652 N N . SER A 1 453 ? 0.660 -1.150 25.358 1.00 27.06 ? 453 SER A N 1 ATOM 3653 C CA . SER A 1 453 ? 1.644 -0.090 25.565 1.00 27.59 ? 453 SER A CA 1 ATOM 3654 C C . SER A 1 453 ? 2.171 -0.042 27.002 1.00 27.49 ? 453 SER A C 1 ATOM 3655 O O . SER A 1 453 ? 3.231 0.532 27.259 1.00 27.51 ? 453 SER A O 1 ATOM 3656 C CB . SER A 1 453 ? 1.094 1.274 25.122 1.00 27.60 ? 453 SER A CB 1 ATOM 3657 O OG . SER A 1 453 ? 0.163 1.782 26.058 1.00 28.74 ? 453 SER A OG 1 ATOM 3658 N N . ILE A 1 454 ? 1.429 -0.646 27.927 1.00 27.38 ? 454 ILE A N 1 ATOM 3659 C CA . ILE A 1 454 ? 1.891 -0.822 29.300 1.00 27.32 ? 454 ILE A CA 1 ATOM 3660 C C . ILE A 1 454 ? 2.700 -2.112 29.392 1.00 27.49 ? 454 ILE A C 1 ATOM 3661 O O . ILE A 1 454 ? 3.791 -2.131 29.975 1.00 27.62 ? 454 ILE A O 1 ATOM 3662 C CB . ILE A 1 454 ? 0.711 -0.844 30.312 1.00 27.56 ? 454 ILE A CB 1 ATOM 3663 C CG1 . ILE A 1 454 ? -0.044 0.493 30.285 1.00 27.50 ? 454 ILE A CG1 1 ATOM 3664 C CG2 . ILE A 1 454 ? 1.213 -1.145 31.735 1.00 26.82 ? 454 ILE A CG2 1 ATOM 3665 C CD1 . ILE A 1 454 ? -1.366 0.478 31.020 1.00 27.14 ? 454 ILE A CD1 1 ATOM 3666 N N . LYS A 1 455 ? 2.166 -3.178 28.797 1.00 27.34 ? 455 LYS A N 1 ATOM 3667 C CA . LYS A 1 455 ? 2.833 -4.476 28.769 1.00 27.23 ? 455 LYS A CA 1 ATOM 3668 C C . LYS A 1 455 ? 4.230 -4.409 28.147 1.00 26.97 ? 455 LYS A C 1 ATOM 3669 O O . LYS A 1 455 ? 5.174 -4.963 28.708 1.00 27.20 ? 455 LYS A O 1 ATOM 3670 C CB . LYS A 1 455 ? 1.967 -5.515 28.047 1.00 27.21 ? 455 LYS A CB 1 ATOM 3671 C CG . LYS A 1 455 ? 2.570 -6.904 27.993 1.00 28.19 ? 455 LYS A CG 1 ATOM 3672 C CD . LYS A 1 455 ? 1.782 -7.848 27.092 1.00 30.07 ? 455 LYS A CD 1 ATOM 3673 C CE . LYS A 1 455 ? 2.393 -9.243 27.122 1.00 31.40 ? 455 LYS A CE 1 ATOM 3674 N NZ . LYS A 1 455 ? 1.857 -10.103 26.036 1.00 33.16 ? 455 LYS A NZ 1 ATOM 3675 N N . TYR A 1 456 ? 4.371 -3.731 27.009 1.00 26.62 ? 456 TYR A N 1 ATOM 3676 C CA . TYR A 1 456 ? 5.654 -3.742 26.289 1.00 26.34 ? 456 TYR A CA 1 ATOM 3677 C C . TYR A 1 456 ? 6.570 -2.575 26.623 1.00 26.56 ? 456 TYR A C 1 ATOM 3678 O O . TYR A 1 456 ? 7.598 -2.398 25.971 1.00 26.61 ? 456 TYR A O 1 ATOM 3679 C CB . TYR A 1 456 ? 5.461 -3.846 24.773 1.00 25.94 ? 456 TYR A CB 1 ATOM 3680 C CG . TYR A 1 456 ? 4.720 -5.085 24.330 1.00 25.26 ? 456 TYR A CG 1 ATOM 3681 C CD1 . TYR A 1 456 ? 5.251 -6.353 24.536 1.00 23.97 ? 456 TYR A CD1 1 ATOM 3682 C CD2 . TYR A 1 456 ? 3.479 -4.984 23.706 1.00 24.00 ? 456 TYR A CD2 1 ATOM 3683 C CE1 . TYR A 1 456 ? 4.566 -7.480 24.131 1.00 23.95 ? 456 TYR A CE1 1 ATOM 3684 C CE2 . TYR A 1 456 ? 2.789 -6.106 23.303 1.00 23.55 ? 456 TYR A CE2 1 ATOM 3685 C CZ . TYR A 1 456 ? 3.334 -7.346 23.515 1.00 23.86 ? 456 TYR A CZ 1 ATOM 3686 O OH . TYR A 1 456 ? 2.628 -8.451 23.107 1.00 24.97 ? 456 TYR A OH 1 ATOM 3687 N N . SER A 1 457 ? 6.203 -1.780 27.630 1.00 26.85 ? 457 SER A N 1 ATOM 3688 C CA . SER A 1 457 ? 7.102 -0.755 28.165 1.00 27.08 ? 457 SER A CA 1 ATOM 3689 C C . SER A 1 457 ? 8.253 -1.417 28.929 1.00 27.53 ? 457 SER A C 1 ATOM 3690 O O . SER A 1 457 ? 8.224 -2.618 29.184 1.00 27.23 ? 457 SER A O 1 ATOM 3691 C CB . SER A 1 457 ? 6.345 0.208 29.080 1.00 27.11 ? 457 SER A CB 1 ATOM 3692 O OG . SER A 1 457 ? 5.928 -0.437 30.266 1.00 26.33 ? 457 SER A OG 1 ATOM 3693 N N . THR A 1 458 ? 9.257 -0.629 29.299 1.00 28.34 ? 458 THR A N 1 ATOM 3694 C CA . THR A 1 458 ? 10.437 -1.166 29.980 1.00 29.06 ? 458 THR A CA 1 ATOM 3695 C C . THR A 1 458 ? 10.370 -0.984 31.494 1.00 29.83 ? 458 THR A C 1 ATOM 3696 O O . THR A 1 458 ? 11.375 -1.120 32.193 1.00 30.31 ? 458 THR A O 1 ATOM 3697 C CB . THR A 1 458 ? 11.747 -0.564 29.424 1.00 28.91 ? 458 THR A CB 1 ATOM 3698 O OG1 . THR A 1 458 ? 11.856 0.807 29.822 1.00 28.82 ? 458 THR A OG1 1 ATOM 3699 C CG2 . THR A 1 458 ? 11.777 -0.660 27.909 1.00 28.27 ? 458 THR A CG2 1 ATOM 3700 N N . LEU A 1 459 ? 9.182 -0.676 32.000 1.00 30.55 ? 459 LEU A N 1 ATOM 3701 C CA . LEU A 1 459 ? 8.976 -0.545 33.431 1.00 31.27 ? 459 LEU A CA 1 ATOM 3702 C C . LEU A 1 459 ? 9.134 -1.889 34.133 1.00 32.37 ? 459 LEU A C 1 ATOM 3703 O O . LEU A 1 459 ? 8.980 -2.948 33.512 1.00 32.49 ? 459 LEU A O 1 ATOM 3704 C CB . LEU A 1 459 ? 7.583 0.014 33.709 1.00 30.85 ? 459 LEU A CB 1 ATOM 3705 C CG . LEU A 1 459 ? 7.287 1.450 33.263 1.00 29.90 ? 459 LEU A CG 1 ATOM 3706 C CD1 . LEU A 1 459 ? 5.796 1.777 33.449 1.00 28.00 ? 459 LEU A CD1 1 ATOM 3707 C CD2 . LEU A 1 459 ? 8.174 2.461 33.987 1.00 27.21 ? 459 LEU A CD2 1 ATOM 3708 N N . LEU A 1 460 ? 9.438 -1.844 35.428 1.00 33.61 ? 460 LEU A N 1 ATOM 3709 C CA . LEU A 1 460 ? 9.411 -3.045 36.261 1.00 34.89 ? 460 LEU A CA 1 ATOM 3710 C C . LEU A 1 460 ? 7.998 -3.611 36.345 1.00 35.69 ? 460 LEU A C 1 ATOM 3711 O O . LEU A 1 460 ? 7.021 -2.868 36.251 1.00 35.82 ? 460 LEU A O 1 ATOM 3712 C CB . LEU A 1 460 ? 9.912 -2.733 37.666 1.00 35.07 ? 460 LEU A CB 1 ATOM 3713 C CG . LEU A 1 460 ? 11.370 -2.310 37.842 1.00 35.10 ? 460 LEU A CG 1 ATOM 3714 C CD1 . LEU A 1 460 ? 11.529 -1.666 39.215 1.00 34.63 ? 460 LEU A CD1 1 ATOM 3715 C CD2 . LEU A 1 460 ? 12.324 -3.489 37.652 1.00 34.31 ? 460 LEU A CD2 1 ATOM 3716 N N . GLU A 1 461 ? 7.895 -4.924 36.535 1.00 36.87 ? 461 GLU A N 1 ATOM 3717 C CA . GLU A 1 461 ? 6.596 -5.595 36.578 1.00 38.25 ? 461 GLU A CA 1 ATOM 3718 C C . GLU A 1 461 ? 5.647 -5.024 37.641 1.00 38.35 ? 461 GLU A C 1 ATOM 3719 O O . GLU A 1 461 ? 4.441 -4.934 37.407 1.00 38.69 ? 461 GLU A O 1 ATOM 3720 C CB . GLU A 1 461 ? 6.770 -7.109 36.734 1.00 38.81 ? 461 GLU A CB 1 ATOM 3721 C CG . GLU A 1 461 ? 7.488 -7.787 35.556 1.00 41.87 ? 461 GLU A CG 1 ATOM 3722 C CD . GLU A 1 461 ? 6.688 -7.750 34.252 1.00 46.52 ? 461 GLU A CD 1 ATOM 3723 O OE1 . GLU A 1 461 ? 5.459 -8.005 34.276 1.00 47.87 ? 461 GLU A OE1 1 ATOM 3724 O OE2 . GLU A 1 461 ? 7.300 -7.474 33.197 1.00 48.17 ? 461 GLU A OE2 1 ATOM 3725 N N . SER A 1 462 ? 6.194 -4.619 38.786 1.00 38.38 ? 462 SER A N 1 ATOM 3726 C CA . SER A 1 462 ? 5.412 -3.971 39.843 1.00 38.61 ? 462 SER A CA 1 ATOM 3727 C C . SER A 1 462 ? 4.990 -2.542 39.485 1.00 38.71 ? 462 SER A C 1 ATOM 3728 O O . SER A 1 462 ? 3.946 -2.062 39.925 1.00 38.90 ? 462 SER A O 1 ATOM 3729 C CB . SER A 1 462 ? 6.197 -3.955 41.150 1.00 38.57 ? 462 SER A CB 1 ATOM 3730 O OG . SER A 1 462 ? 7.444 -3.321 40.968 1.00 39.35 ? 462 SER A OG 1 ATOM 3731 N N . GLU A 1 463 ? 5.814 -1.857 38.701 1.00 38.67 ? 463 GLU A N 1 ATOM 3732 C CA . GLU A 1 463 ? 5.445 -0.550 38.167 1.00 38.54 ? 463 GLU A CA 1 ATOM 3733 C C . GLU A 1 463 ? 4.361 -0.692 37.089 1.00 37.98 ? 463 GLU A C 1 ATOM 3734 O O . GLU A 1 463 ? 3.470 0.150 36.990 1.00 37.59 ? 463 GLU A O 1 ATOM 3735 C CB . GLU A 1 463 ? 6.674 0.175 37.618 1.00 38.87 ? 463 GLU A CB 1 ATOM 3736 C CG . GLU A 1 463 ? 7.652 0.638 38.695 1.00 40.46 ? 463 GLU A CG 1 ATOM 3737 C CD . GLU A 1 463 ? 9.061 0.938 38.162 1.00 43.34 ? 463 GLU A CD 1 ATOM 3738 O OE1 . GLU A 1 463 ? 9.416 0.505 37.039 1.00 44.31 ? 463 GLU A OE1 1 ATOM 3739 O OE2 . GLU A 1 463 ? 9.828 1.609 38.888 1.00 44.41 ? 463 GLU A OE2 1 ATOM 3740 N N . LYS A 1 464 ? 4.431 -1.768 36.300 1.00 37.47 ? 464 LYS A N 1 ATOM 3741 C CA . LYS A 1 464 ? 3.392 -2.068 35.308 1.00 37.00 ? 464 LYS A CA 1 ATOM 3742 C C . LYS A 1 464 ? 2.015 -2.265 35.962 1.00 37.23 ? 464 LYS A C 1 ATOM 3743 O O . LYS A 1 464 ? 1.014 -1.742 35.458 1.00 36.85 ? 464 LYS A O 1 ATOM 3744 C CB . LYS A 1 464 ? 3.773 -3.278 34.450 1.00 36.68 ? 464 LYS A CB 1 ATOM 3745 C CG . LYS A 1 464 ? 4.882 -3.006 33.445 1.00 35.47 ? 464 LYS A CG 1 ATOM 3746 C CD . LYS A 1 464 ? 5.146 -4.211 32.580 1.00 34.53 ? 464 LYS A CD 1 ATOM 3747 C CE . LYS A 1 464 ? 6.439 -4.057 31.804 1.00 34.97 ? 464 LYS A CE 1 ATOM 3748 N NZ . LYS A 1 464 ? 6.689 -5.214 30.901 1.00 35.03 ? 464 LYS A NZ 1 ATOM 3749 N N . ASN A 1 465 ? 1.975 -2.999 37.081 1.00 37.41 ? 465 ASN A N 1 ATOM 3750 C CA . ASN A 1 465 ? 0.744 -3.184 37.862 1.00 37.78 ? 465 ASN A CA 1 ATOM 3751 C C . ASN A 1 465 ? 0.134 -1.876 38.329 1.00 37.57 ? 465 ASN A C 1 ATOM 3752 O O . ASN A 1 465 ? -1.066 -1.659 38.165 1.00 37.56 ? 465 ASN A O 1 ATOM 3753 C CB . ASN A 1 465 ? 0.988 -4.052 39.093 1.00 38.14 ? 465 ASN A CB 1 ATOM 3754 C CG . ASN A 1 465 ? 1.509 -5.423 38.750 1.00 39.80 ? 465 ASN A CG 1 ATOM 3755 O OD1 . ASN A 1 465 ? 1.000 -6.099 37.850 1.00 42.02 ? 465 ASN A OD1 1 ATOM 3756 N ND2 . ASN A 1 465 ? 2.530 -5.853 39.479 1.00 41.87 ? 465 ASN A ND2 1 ATOM 3757 N N . THR A 1 466 ? 0.962 -1.022 38.929 1.00 37.34 ? 466 THR A N 1 ATOM 3758 C CA . THR A 1 466 ? 0.529 0.305 39.379 1.00 37.36 ? 466 THR A CA 1 ATOM 3759 C C . THR A 1 466 ? -0.020 1.132 38.212 1.00 37.43 ? 466 THR A C 1 ATOM 3760 O O . THR A 1 466 ? -1.027 1.827 38.361 1.00 37.27 ? 466 THR A O 1 ATOM 3761 C CB . THR A 1 466 ? 1.690 1.071 40.054 1.00 37.30 ? 466 THR A CB 1 ATOM 3762 O OG1 . THR A 1 466 ? 2.269 0.259 41.083 1.00 37.69 ? 466 THR A OG1 1 ATOM 3763 C CG2 . THR A 1 466 ? 1.215 2.382 40.651 1.00 36.88 ? 466 THR A CG2 1 ATOM 3764 N N . PHE A 1 467 ? 0.660 1.042 37.064 1.00 37.64 ? 467 PHE A N 1 ATOM 3765 C CA . PHE A 1 467 ? 0.268 1.706 35.821 1.00 37.79 ? 467 PHE A CA 1 ATOM 3766 C C . PHE A 1 467 ? -1.085 1.169 35.349 1.00 38.05 ? 467 PHE A C 1 ATOM 3767 O O . PHE A 1 467 ? -1.988 1.946 35.037 1.00 37.88 ? 467 PHE A O 1 ATOM 3768 C CB . PHE A 1 467 ? 1.343 1.481 34.747 1.00 37.75 ? 467 PHE A CB 1 ATOM 3769 C CG . PHE A 1 467 ? 1.281 2.440 33.574 1.00 37.83 ? 467 PHE A CG 1 ATOM 3770 C CD1 . PHE A 1 467 ? 0.172 3.256 33.347 1.00 37.64 ? 467 PHE A CD1 1 ATOM 3771 C CD2 . PHE A 1 467 ? 2.333 2.490 32.668 1.00 38.22 ? 467 PHE A CD2 1 ATOM 3772 C CE1 . PHE A 1 467 ? 0.129 4.115 32.262 1.00 37.01 ? 467 PHE A CE1 1 ATOM 3773 C CE2 . PHE A 1 467 ? 2.298 3.346 31.579 1.00 37.63 ? 467 PHE A CE2 1 ATOM 3774 C CZ . PHE A 1 467 ? 1.195 4.161 31.374 1.00 37.43 ? 467 PHE A CZ 1 ATOM 3775 N N . MET A 1 468 ? -1.225 -0.154 35.317 1.00 38.53 ? 468 MET A N 1 ATOM 3776 C CA . MET A 1 468 ? -2.492 -0.785 34.949 1.00 39.34 ? 468 MET A CA 1 ATOM 3777 C C . MET A 1 468 ? -3.646 -0.326 35.851 1.00 39.50 ? 468 MET A C 1 ATOM 3778 O O . MET A 1 468 ? -4.732 0.002 35.364 1.00 39.48 ? 468 MET A O 1 ATOM 3779 C CB . MET A 1 468 ? -2.368 -2.307 34.965 1.00 39.57 ? 468 MET A CB 1 ATOM 3780 C CG . MET A 1 468 ? -3.495 -3.015 34.236 1.00 41.44 ? 468 MET A CG 1 ATOM 3781 S SD . MET A 1 468 ? -3.438 -2.683 32.463 1.00 44.82 ? 468 MET A SD 1 ATOM 3782 C CE . MET A 1 468 ? -2.273 -3.940 31.906 1.00 44.71 ? 468 MET A CE 1 ATOM 3783 N N . GLU A 1 469 ? -3.388 -0.289 37.159 1.00 39.59 ? 469 GLU A N 1 ATOM 3784 C CA . GLU A 1 469 ? -4.338 0.197 38.161 1.00 39.67 ? 469 GLU A CA 1 ATOM 3785 C C . GLU A 1 469 ? -4.847 1.612 37.856 1.00 38.69 ? 469 GLU A C 1 ATOM 3786 O O . GLU A 1 469 ? -6.058 1.857 37.836 1.00 38.61 ? 469 GLU A O 1 ATOM 3787 C CB . GLU A 1 469 ? -3.672 0.208 39.531 1.00 40.14 ? 469 GLU A CB 1 ATOM 3788 C CG . GLU A 1 469 ? -4.458 -0.490 40.591 1.00 43.99 ? 469 GLU A CG 1 ATOM 3789 C CD . GLU A 1 469 ? -4.003 -1.921 40.758 1.00 49.00 ? 469 GLU A CD 1 ATOM 3790 O OE1 . GLU A 1 469 ? -3.063 -2.154 41.560 1.00 50.84 ? 469 GLU A OE1 1 ATOM 3791 O OE2 . GLU A 1 469 ? -4.580 -2.807 40.084 1.00 50.61 ? 469 GLU A OE2 1 ATOM 3792 N N . ILE A 1 470 ? -3.908 2.531 37.633 1.00 37.58 ? 470 ILE A N 1 ATOM 3793 C CA . ILE A 1 470 ? -4.211 3.926 37.313 1.00 36.53 ? 470 ILE A CA 1 ATOM 3794 C C . ILE A 1 470 ? -4.976 4.036 35.992 1.00 36.30 ? 470 ILE A C 1 ATOM 3795 O O . ILE A 1 470 ? -5.974 4.761 35.902 1.00 36.36 ? 470 ILE A O 1 ATOM 3796 C CB . ILE A 1 470 ? -2.923 4.775 37.265 1.00 36.34 ? 470 ILE A CB 1 ATOM 3797 C CG1 . ILE A 1 470 ? -2.329 4.908 38.672 1.00 35.90 ? 470 ILE A CG1 1 ATOM 3798 C CG2 . ILE A 1 470 ? -3.187 6.153 36.650 1.00 35.85 ? 470 ILE A CG2 1 ATOM 3799 C CD1 . ILE A 1 470 ? -0.883 5.379 38.709 1.00 35.07 ? 470 ILE A CD1 1 ATOM 3800 N N . TRP A 1 471 ? -4.506 3.303 34.981 1.00 35.78 ? 471 TRP A N 1 ATOM 3801 C CA . TRP A 1 471 ? -5.137 3.284 33.663 1.00 35.29 ? 471 TRP A CA 1 ATOM 3802 C C . TRP A 1 471 ? -6.575 2.724 33.684 1.00 35.74 ? 471 TRP A C 1 ATOM 3803 O O . TRP A 1 471 ? -7.464 3.273 33.023 1.00 35.61 ? 471 TRP A O 1 ATOM 3804 C CB . TRP A 1 471 ? -4.256 2.541 32.633 1.00 34.52 ? 471 TRP A CB 1 ATOM 3805 C CG . TRP A 1 471 ? -4.947 2.373 31.319 1.00 32.30 ? 471 TRP A CG 1 ATOM 3806 C CD1 . TRP A 1 471 ? -4.936 3.244 30.263 1.00 30.96 ? 471 TRP A CD1 1 ATOM 3807 C CD2 . TRP A 1 471 ? -5.797 1.290 30.935 1.00 30.62 ? 471 TRP A CD2 1 ATOM 3808 N NE1 . TRP A 1 471 ? -5.710 2.758 29.240 1.00 30.12 ? 471 TRP A NE1 1 ATOM 3809 C CE2 . TRP A 1 471 ? -6.256 1.562 29.628 1.00 30.28 ? 471 TRP A CE2 1 ATOM 3810 C CE3 . TRP A 1 471 ? -6.208 0.108 31.565 1.00 29.93 ? 471 TRP A CE3 1 ATOM 3811 C CZ2 . TRP A 1 471 ? -7.106 0.696 28.939 1.00 30.08 ? 471 TRP A CZ2 1 ATOM 3812 C CZ3 . TRP A 1 471 ? -7.052 -0.752 30.879 1.00 29.93 ? 471 TRP A CZ3 1 ATOM 3813 C CH2 . TRP A 1 471 ? -7.492 -0.454 29.581 1.00 30.47 ? 471 TRP A CH2 1 ATOM 3814 N N . LYS A 1 472 ? -6.792 1.640 34.435 1.00 36.39 ? 472 LYS A N 1 ATOM 3815 C CA . LYS A 1 472 ? -8.116 0.995 34.544 1.00 37.07 ? 472 LYS A CA 1 ATOM 3816 C C . LYS A 1 472 ? -9.188 1.962 35.067 1.00 37.13 ? 472 LYS A C 1 ATOM 3817 O O . LYS A 1 472 ? -10.320 1.973 34.575 1.00 36.84 ? 472 LYS A O 1 ATOM 3818 C CB . LYS A 1 472 ? -8.043 -0.277 35.408 1.00 37.20 ? 472 LYS A CB 1 ATOM 3819 C CG . LYS A 1 472 ? -9.313 -1.140 35.445 1.00 39.05 ? 472 LYS A CG 1 ATOM 3820 C CD . LYS A 1 472 ? -9.662 -1.726 34.070 1.00 42.84 ? 472 LYS A CD 1 ATOM 3821 C CE . LYS A 1 472 ? -10.957 -2.551 34.087 1.00 44.46 ? 472 LYS A CE 1 ATOM 3822 N NZ . LYS A 1 472 ? -12.171 -1.757 34.478 1.00 45.01 ? 472 LYS A NZ 1 ATOM 3823 N N . LYS A 1 473 ? -8.811 2.780 36.047 1.00 37.36 ? 473 LYS A N 1 ATOM 3824 C CA . LYS A 1 473 ? -9.707 3.789 36.609 1.00 37.95 ? 473 LYS A CA 1 ATOM 3825 C C . LYS A 1 473 ? -10.060 4.884 35.609 1.00 37.66 ? 473 LYS A C 1 ATOM 3826 O O . LYS A 1 473 ? -11.224 5.308 35.525 1.00 37.79 ? 473 LYS A O 1 ATOM 3827 C CB . LYS A 1 473 ? -9.113 4.403 37.876 1.00 38.20 ? 473 LYS A CB 1 ATOM 3828 C CG . LYS A 1 473 ? -9.377 3.593 39.117 1.00 40.61 ? 473 LYS A CG 1 ATOM 3829 C CD . LYS A 1 473 ? -9.143 4.440 40.355 1.00 46.04 ? 473 LYS A CD 1 ATOM 3830 C CE . LYS A 1 473 ? -10.306 4.320 41.352 1.00 48.58 ? 473 LYS A CE 1 ATOM 3831 N NZ . LYS A 1 473 ? -10.108 3.225 42.351 1.00 50.48 ? 473 LYS A NZ 1 ATOM 3832 N N . ARG A 1 474 ? -9.059 5.345 34.859 1.00 37.21 ? 474 ARG A N 1 ATOM 3833 C CA . ARG A 1 474 ? -9.299 6.302 33.776 1.00 36.65 ? 474 ARG A CA 1 ATOM 3834 C C . ARG A 1 474 ? -10.151 5.677 32.667 1.00 36.32 ? 474 ARG A C 1 ATOM 3835 O O . ARG A 1 474 ? -10.963 6.360 32.044 1.00 36.13 ? 474 ARG A O 1 ATOM 3836 C CB . ARG A 1 474 ? -7.980 6.830 33.217 1.00 36.57 ? 474 ARG A CB 1 ATOM 3837 C CG . ARG A 1 474 ? -7.271 7.796 34.141 1.00 36.23 ? 474 ARG A CG 1 ATOM 3838 C CD . ARG A 1 474 ? -6.380 8.747 33.357 1.00 36.70 ? 474 ARG A CD 1 ATOM 3839 N NE . ARG A 1 474 ? -5.904 9.849 34.191 1.00 36.85 ? 474 ARG A NE 1 ATOM 3840 C CZ . ARG A 1 474 ? -5.603 11.065 33.743 1.00 36.83 ? 474 ARG A CZ 1 ATOM 3841 N NH1 . ARG A 1 474 ? -5.730 11.369 32.458 1.00 36.25 ? 474 ARG A NH1 1 ATOM 3842 N NH2 . ARG A 1 474 ? -5.182 11.991 34.593 1.00 37.66 ? 474 ARG A NH2 1 ATOM 3843 N N . TRP A 1 475 ? -9.968 4.373 32.450 1.00 35.90 ? 475 TRP A N 1 ATOM 3844 C CA . TRP A 1 475 ? -10.720 3.626 31.449 1.00 35.86 ? 475 TRP A CA 1 ATOM 3845 C C . TRP A 1 475 ? -12.208 3.559 31.790 1.00 35.96 ? 475 TRP A C 1 ATOM 3846 O O . TRP A 1 475 ? -13.050 3.890 30.960 1.00 36.28 ? 475 TRP A O 1 ATOM 3847 C CB . TRP A 1 475 ? -10.117 2.227 31.234 1.00 35.68 ? 475 TRP A CB 1 ATOM 3848 C CG . TRP A 1 475 ? -10.854 1.398 30.231 1.00 35.37 ? 475 TRP A CG 1 ATOM 3849 C CD1 . TRP A 1 475 ? -11.772 0.427 30.498 1.00 36.03 ? 475 TRP A CD1 1 ATOM 3850 C CD2 . TRP A 1 475 ? -10.747 1.468 28.800 1.00 35.29 ? 475 TRP A CD2 1 ATOM 3851 N NE1 . TRP A 1 475 ? -12.244 -0.115 29.327 1.00 36.31 ? 475 TRP A NE1 1 ATOM 3852 C CE2 . TRP A 1 475 ? -11.635 0.506 28.268 1.00 35.66 ? 475 TRP A CE2 1 ATOM 3853 C CE3 . TRP A 1 475 ? -9.987 2.248 27.914 1.00 34.86 ? 475 TRP A CE3 1 ATOM 3854 C CZ2 . TRP A 1 475 ? -11.790 0.304 26.891 1.00 35.12 ? 475 TRP A CZ2 1 ATOM 3855 C CZ3 . TRP A 1 475 ? -10.141 2.047 26.543 1.00 34.77 ? 475 TRP A CZ3 1 ATOM 3856 C CH2 . TRP A 1 475 ? -11.038 1.082 26.047 1.00 34.79 ? 475 TRP A CH2 1 ATOM 3857 N N . ASP A 1 476 ? -12.527 3.143 33.009 1.00 36.14 ? 476 ASP A N 1 ATOM 3858 C CA . ASP A 1 476 ? -13.914 3.109 33.483 1.00 36.36 ? 476 ASP A CA 1 ATOM 3859 C C . ASP A 1 476 ? -14.627 4.453 33.350 1.00 36.22 ? 476 ASP A C 1 ATOM 3860 O O . ASP A 1 476 ? -15.778 4.508 32.894 1.00 36.07 ? 476 ASP A O 1 ATOM 3861 C CB . ASP A 1 476 ? -13.963 2.627 34.928 1.00 36.48 ? 476 ASP A CB 1 ATOM 3862 C CG . ASP A 1 476 ? -13.416 1.235 35.080 1.00 37.40 ? 476 ASP A CG 1 ATOM 3863 O OD1 . ASP A 1 476 ? -13.494 0.465 34.109 1.00 39.08 ? 476 ASP A OD1 1 ATOM 3864 O OD2 . ASP A 1 476 ? -12.899 0.906 36.163 1.00 39.53 ? 476 ASP A OD2 1 ATOM 3865 N N . LYS A 1 477 ? -13.936 5.525 33.734 1.00 36.14 ? 477 LYS A N 1 ATOM 3866 C CA . LYS A 1 477 ? -14.454 6.886 33.584 1.00 36.46 ? 477 LYS A CA 1 ATOM 3867 C C . LYS A 1 477 ? -14.747 7.209 32.120 1.00 36.11 ? 477 LYS A C 1 ATOM 3868 O O . LYS A 1 477 ? -15.778 7.804 31.801 1.00 36.26 ? 477 LYS A O 1 ATOM 3869 C CB . LYS A 1 477 ? -13.476 7.910 34.188 1.00 36.82 ? 477 LYS A CB 1 ATOM 3870 C CG . LYS A 1 477 ? -13.762 9.378 33.837 1.00 38.15 ? 477 LYS A CG 1 ATOM 3871 C CD . LYS A 1 477 ? -14.959 9.919 34.620 1.00 41.70 ? 477 LYS A CD 1 ATOM 3872 C CE . LYS A 1 477 ? -15.664 11.079 33.895 1.00 43.86 ? 477 LYS A CE 1 ATOM 3873 N NZ . LYS A 1 477 ? -14.910 12.372 33.944 1.00 44.54 ? 477 LYS A NZ 1 ATOM 3874 N N . PHE A 1 478 ? -13.829 6.810 31.243 1.00 35.67 ? 478 PHE A N 1 ATOM 3875 C CA . PHE A 1 478 ? -13.974 7.006 29.806 1.00 35.23 ? 478 PHE A CA 1 ATOM 3876 C C . PHE A 1 478 ? -15.188 6.230 29.291 1.00 35.29 ? 478 PHE A C 1 ATOM 3877 O O . PHE A 1 478 ? -16.017 6.783 28.573 1.00 35.14 ? 478 PHE A O 1 ATOM 3878 C CB . PHE A 1 478 ? -12.673 6.593 29.093 1.00 34.88 ? 478 PHE A CB 1 ATOM 3879 C CG . PHE A 1 478 ? -12.801 6.447 27.603 1.00 33.78 ? 478 PHE A CG 1 ATOM 3880 C CD1 . PHE A 1 478 ? -12.897 7.570 26.782 1.00 32.46 ? 478 PHE A CD1 1 ATOM 3881 C CD2 . PHE A 1 478 ? -12.796 5.176 27.011 1.00 32.82 ? 478 PHE A CD2 1 ATOM 3882 C CE1 . PHE A 1 478 ? -13.010 7.430 25.391 1.00 32.13 ? 478 PHE A CE1 1 ATOM 3883 C CE2 . PHE A 1 478 ? -12.907 5.027 25.619 1.00 31.33 ? 478 PHE A CE2 1 ATOM 3884 C CZ . PHE A 1 478 ? -13.017 6.156 24.813 1.00 31.27 ? 478 PHE A CZ 1 ATOM 3885 N N . ILE A 1 479 ? -15.292 4.961 29.687 1.00 35.55 ? 479 ILE A N 1 ATOM 3886 C CA . ILE A 1 479 ? -16.424 4.100 29.320 1.00 36.09 ? 479 ILE A CA 1 ATOM 3887 C C . ILE A 1 479 ? -17.777 4.710 29.694 1.00 36.57 ? 479 ILE A C 1 ATOM 3888 O O . ILE A 1 479 ? -18.702 4.730 28.877 1.00 36.48 ? 479 ILE A O 1 ATOM 3889 C CB . ILE A 1 479 ? -16.302 2.687 29.953 1.00 35.83 ? 479 ILE A CB 1 ATOM 3890 C CG1 . ILE A 1 479 ? -15.084 1.931 29.386 1.00 36.00 ? 479 ILE A CG1 1 ATOM 3891 C CG2 . ILE A 1 479 ? -17.587 1.894 29.774 1.00 35.29 ? 479 ILE A CG2 1 ATOM 3892 C CD1 . ILE A 1 479 ? -14.973 1.909 27.855 1.00 35.26 ? 479 ILE A CD1 1 ATOM 3893 N N . ALA A 1 480 ? -17.872 5.208 30.927 1.00 37.31 ? 480 ALA A N 1 ATOM 3894 C CA . ALA A 1 480 ? -19.103 5.798 31.450 1.00 37.91 ? 480 ALA A CA 1 ATOM 3895 C C . ALA A 1 480 ? -19.509 7.057 30.687 1.00 38.47 ? 480 ALA A C 1 ATOM 3896 O O . ALA A 1 480 ? -20.700 7.276 30.448 1.00 38.62 ? 480 ALA A O 1 ATOM 3897 C CB . ALA A 1 480 ? -18.958 6.087 32.928 1.00 37.73 ? 480 ALA A CB 1 ATOM 3898 N N . ASP A 1 481 ? -18.521 7.871 30.305 1.00 39.17 ? 481 ASP A N 1 ATOM 3899 C CA . ASP A 1 481 ? -18.754 9.055 29.471 1.00 39.96 ? 481 ASP A CA 1 ATOM 3900 C C . ASP A 1 481 ? -19.335 8.690 28.112 1.00 39.94 ? 481 ASP A C 1 ATOM 3901 O O . ASP A 1 481 ? -20.374 9.210 27.726 1.00 40.13 ? 481 ASP A O 1 ATOM 3902 C CB . ASP A 1 481 ? -17.461 9.848 29.267 1.00 40.44 ? 481 ASP A CB 1 ATOM 3903 C CG . ASP A 1 481 ? -17.072 10.676 30.482 1.00 42.59 ? 481 ASP A CG 1 ATOM 3904 O OD1 . ASP A 1 481 ? -17.945 10.964 31.339 1.00 44.73 ? 481 ASP A OD1 1 ATOM 3905 O OD2 . ASP A 1 481 ? -15.880 11.053 30.567 1.00 44.54 ? 481 ASP A OD2 1 ATOM 3906 N N . VAL A 1 482 ? -18.663 7.788 27.398 1.00 40.06 ? 482 VAL A N 1 ATOM 3907 C CA . VAL A 1 482 ? -19.044 7.429 26.029 1.00 39.99 ? 482 VAL A CA 1 ATOM 3908 C C . VAL A 1 482 ? -20.398 6.736 26.019 1.00 40.27 ? 482 VAL A C 1 ATOM 3909 O O . VAL A 1 482 ? -21.189 6.922 25.095 1.00 39.95 ? 482 VAL A O 1 ATOM 3910 C CB . VAL A 1 482 ? -17.970 6.549 25.337 1.00 40.01 ? 482 VAL A CB 1 ATOM 3911 C CG1 . VAL A 1 482 ? -18.407 6.178 23.915 1.00 39.80 ? 482 VAL A CG1 1 ATOM 3912 C CG2 . VAL A 1 482 ? -16.624 7.266 25.309 1.00 38.98 ? 482 VAL A CG2 1 ATOM 3913 N N . ALA A 1 483 ? -20.658 5.954 27.065 1.00 40.79 ? 483 ALA A N 1 ATOM 3914 C CA . ALA A 1 483 ? -21.948 5.295 27.243 1.00 41.47 ? 483 ALA A CA 1 ATOM 3915 C C . ALA A 1 483 ? -23.087 6.301 27.462 1.00 41.95 ? 483 ALA A C 1 ATOM 3916 O O . ALA A 1 483 ? -24.248 5.974 27.237 1.00 42.13 ? 483 ALA A O 1 ATOM 3917 C CB . ALA A 1 483 ? -21.883 4.281 28.378 1.00 41.33 ? 483 ALA A CB 1 ATOM 3918 N N . THR A 1 484 ? -22.750 7.519 27.888 1.00 42.55 ? 484 THR A N 1 ATOM 3919 C CA . THR A 1 484 ? -23.719 8.621 27.910 1.00 43.19 ? 484 THR A CA 1 ATOM 3920 C C . THR A 1 484 ? -23.188 9.856 27.172 1.00 43.31 ? 484 THR A C 1 ATOM 3921 O O . THR A 1 484 ? -23.088 10.951 27.728 1.00 43.29 ? 484 THR A O 1 ATOM 3922 C CB . THR A 1 484 ? -24.152 9.000 29.330 1.00 43.35 ? 484 THR A CB 1 ATOM 3923 O OG1 . THR A 1 484 ? -23.986 7.878 30.211 1.00 43.77 ? 484 THR A OG1 1 ATOM 3924 C CG2 . THR A 1 484 ? -25.616 9.450 29.316 1.00 43.95 ? 484 THR A CG2 1 ATOM 3925 N N . SER B 1 3 ? 25.725 -20.267 16.282 1.00 54.92 ? 3 SER B N 1 ATOM 3926 C CA . SER B 1 3 ? 24.379 -20.779 16.674 1.00 55.17 ? 3 SER B CA 1 ATOM 3927 C C . SER B 1 3 ? 23.273 -19.772 16.342 1.00 55.19 ? 3 SER B C 1 ATOM 3928 O O . SER B 1 3 ? 22.263 -20.122 15.719 1.00 55.32 ? 3 SER B O 1 ATOM 3929 C CB . SER B 1 3 ? 24.350 -21.131 18.162 1.00 55.21 ? 3 SER B CB 1 ATOM 3930 O OG . SER B 1 3 ? 23.059 -21.573 18.545 1.00 55.46 ? 3 SER B OG 1 ATOM 3931 N N . ILE B 1 4 ? 23.467 -18.524 16.766 1.00 54.92 ? 4 ILE B N 1 ATOM 3932 C CA . ILE B 1 4 ? 22.578 -17.432 16.378 1.00 54.63 ? 4 ILE B CA 1 ATOM 3933 C C . ILE B 1 4 ? 22.692 -17.209 14.864 1.00 54.42 ? 4 ILE B C 1 ATOM 3934 O O . ILE B 1 4 ? 21.689 -16.951 14.192 1.00 54.51 ? 4 ILE B O 1 ATOM 3935 C CB . ILE B 1 4 ? 22.861 -16.133 17.189 1.00 54.75 ? 4 ILE B CB 1 ATOM 3936 C CG1 . ILE B 1 4 ? 22.551 -16.356 18.673 1.00 54.67 ? 4 ILE B CG1 1 ATOM 3937 C CG2 . ILE B 1 4 ? 22.037 -14.951 16.658 1.00 54.82 ? 4 ILE B CG2 1 ATOM 3938 C CD1 . ILE B 1 4 ? 22.946 -15.205 19.570 1.00 54.81 ? 4 ILE B CD1 1 ATOM 3939 N N . ASP B 1 5 ? 23.911 -17.339 14.338 1.00 54.04 ? 5 ASP B N 1 ATOM 3940 C CA . ASP B 1 5 ? 24.153 -17.367 12.890 1.00 53.65 ? 5 ASP B CA 1 ATOM 3941 C C . ASP B 1 5 ? 23.317 -18.432 12.190 1.00 52.88 ? 5 ASP B C 1 ATOM 3942 O O . ASP B 1 5 ? 22.861 -18.231 11.065 1.00 52.71 ? 5 ASP B O 1 ATOM 3943 C CB . ASP B 1 5 ? 25.625 -17.651 12.599 1.00 54.05 ? 5 ASP B CB 1 ATOM 3944 C CG . ASP B 1 5 ? 26.516 -16.476 12.911 1.00 55.28 ? 5 ASP B CG 1 ATOM 3945 O OD1 . ASP B 1 5 ? 27.084 -15.899 11.957 1.00 56.47 ? 5 ASP B OD1 1 ATOM 3946 O OD2 . ASP B 1 5 ? 26.642 -16.127 14.106 1.00 56.79 ? 5 ASP B OD2 1 ATOM 3947 N N . GLU B 1 6 ? 23.143 -19.566 12.862 1.00 51.90 ? 6 GLU B N 1 ATOM 3948 C CA . GLU B 1 6 ? 22.375 -20.675 12.324 1.00 51.01 ? 6 GLU B CA 1 ATOM 3949 C C . GLU B 1 6 ? 20.881 -20.382 12.332 1.00 49.64 ? 6 GLU B C 1 ATOM 3950 O O . GLU B 1 6 ? 20.169 -20.780 11.413 1.00 49.52 ? 6 GLU B O 1 ATOM 3951 C CB . GLU B 1 6 ? 22.679 -21.957 13.100 1.00 51.50 ? 6 GLU B CB 1 ATOM 3952 C CG . GLU B 1 6 ? 23.998 -22.602 12.703 1.00 53.34 ? 6 GLU B CG 1 ATOM 3953 C CD . GLU B 1 6 ? 24.492 -23.629 13.709 1.00 56.02 ? 6 GLU B CD 1 ATOM 3954 O OE1 . GLU B 1 6 ? 23.668 -24.203 14.459 1.00 56.95 ? 6 GLU B OE1 1 ATOM 3955 O OE2 . GLU B 1 6 ? 25.720 -23.864 13.743 1.00 57.00 ? 6 GLU B OE2 1 ATOM 3956 N N . THR B 1 7 ? 20.418 -19.689 13.373 1.00 48.03 ? 7 THR B N 1 ATOM 3957 C CA . THR B 1 7 ? 19.018 -19.267 13.470 1.00 46.17 ? 7 THR B CA 1 ATOM 3958 C C . THR B 1 7 ? 18.710 -18.293 12.339 1.00 44.87 ? 7 THR B C 1 ATOM 3959 O O . THR B 1 7 ? 17.676 -18.399 11.669 1.00 44.63 ? 7 THR B O 1 ATOM 3960 C CB . THR B 1 7 ? 18.722 -18.594 14.826 1.00 46.18 ? 7 THR B CB 1 ATOM 3961 O OG1 . THR B 1 7 ? 19.251 -19.400 15.884 1.00 46.32 ? 7 THR B OG1 1 ATOM 3962 C CG2 . THR B 1 7 ? 17.220 -18.418 15.031 1.00 46.04 ? 7 THR B CG2 1 ATOM 3963 N N . ARG B 1 8 ? 19.632 -17.358 12.131 1.00 43.06 ? 8 ARG B N 1 ATOM 3964 C CA . ARG B 1 8 ? 19.519 -16.367 11.078 1.00 41.42 ? 8 ARG B CA 1 ATOM 3965 C C . ARG B 1 8 ? 19.468 -17.015 9.685 1.00 40.93 ? 8 ARG B C 1 ATOM 3966 O O . ARG B 1 8 ? 18.609 -16.669 8.867 1.00 40.91 ? 8 ARG B O 1 ATOM 3967 C CB . ARG B 1 8 ? 20.678 -15.380 11.176 1.00 41.01 ? 8 ARG B CB 1 ATOM 3968 C CG . ARG B 1 8 ? 20.568 -14.200 10.249 1.00 39.13 ? 8 ARG B CG 1 ATOM 3969 C CD . ARG B 1 8 ? 21.899 -13.529 10.132 1.00 36.06 ? 8 ARG B CD 1 ATOM 3970 N NE . ARG B 1 8 ? 21.806 -12.200 9.545 1.00 34.65 ? 8 ARG B NE 1 ATOM 3971 C CZ . ARG B 1 8 ? 21.932 -11.931 8.248 1.00 35.50 ? 8 ARG B CZ 1 ATOM 3972 N NH1 . ARG B 1 8 ? 22.146 -12.908 7.367 1.00 36.45 ? 8 ARG B NH1 1 ATOM 3973 N NH2 . ARG B 1 8 ? 21.842 -10.675 7.825 1.00 34.40 ? 8 ARG B NH2 1 ATOM 3974 N N . ALA B 1 9 ? 20.383 -17.950 9.426 1.00 40.07 ? 9 ALA B N 1 ATOM 3975 C CA . ALA B 1 9 ? 20.446 -18.652 8.141 1.00 39.26 ? 9 ALA B CA 1 ATOM 3976 C C . ALA B 1 9 ? 19.214 -19.516 7.913 1.00 38.61 ? 9 ALA B C 1 ATOM 3977 O O . ALA B 1 9 ? 18.756 -19.662 6.777 1.00 38.17 ? 9 ALA B O 1 ATOM 3978 C CB . ALA B 1 9 ? 21.715 -19.494 8.044 1.00 39.16 ? 9 ALA B CB 1 ATOM 3979 N N . HIS B 1 10 ? 18.689 -20.078 9.004 1.00 38.12 ? 10 HIS B N 1 ATOM 3980 C CA . HIS B 1 10 ? 17.506 -20.937 8.966 1.00 37.71 ? 10 HIS B CA 1 ATOM 3981 C C . HIS B 1 10 ? 16.257 -20.153 8.557 1.00 36.89 ? 10 HIS B C 1 ATOM 3982 O O . HIS B 1 10 ? 15.464 -20.622 7.736 1.00 36.78 ? 10 HIS B O 1 ATOM 3983 C CB . HIS B 1 10 ? 17.295 -21.638 10.315 1.00 37.85 ? 10 HIS B CB 1 ATOM 3984 C CG . HIS B 1 10 ? 16.048 -22.461 10.379 1.00 39.65 ? 10 HIS B CG 1 ATOM 3985 N ND1 . HIS B 1 10 ? 15.922 -23.674 9.733 1.00 41.69 ? 10 HIS B ND1 1 ATOM 3986 C CD2 . HIS B 1 10 ? 14.865 -22.242 11.002 1.00 41.01 ? 10 HIS B CD2 1 ATOM 3987 C CE1 . HIS B 1 10 ? 14.715 -24.166 9.957 1.00 42.24 ? 10 HIS B CE1 1 ATOM 3988 N NE2 . HIS B 1 10 ? 14.056 -23.319 10.729 1.00 42.00 ? 10 HIS B NE2 1 ATOM 3989 N N . LEU B 1 11 ? 16.104 -18.958 9.129 1.00 36.14 ? 11 LEU B N 1 ATOM 3990 C CA . LEU B 1 11 ? 14.981 -18.069 8.822 1.00 35.12 ? 11 LEU B CA 1 ATOM 3991 C C . LEU B 1 11 ? 15.012 -17.593 7.367 1.00 35.02 ? 11 LEU B C 1 ATOM 3992 O O . LEU B 1 11 ? 13.973 -17.545 6.693 1.00 35.02 ? 11 LEU B O 1 ATOM 3993 C CB . LEU B 1 11 ? 14.934 -16.897 9.809 1.00 34.56 ? 11 LEU B CB 1 ATOM 3994 C CG . LEU B 1 11 ? 14.530 -17.294 11.241 1.00 33.97 ? 11 LEU B CG 1 ATOM 3995 C CD1 . LEU B 1 11 ? 14.952 -16.260 12.281 1.00 33.15 ? 11 LEU B CD1 1 ATOM 3996 C CD2 . LEU B 1 11 ? 13.041 -17.590 11.367 1.00 32.60 ? 11 LEU B CD2 1 ATOM 3997 N N . LEU B 1 12 ? 16.207 -17.270 6.879 1.00 34.71 ? 12 LEU B N 1 ATOM 3998 C CA . LEU B 1 12 ? 16.380 -16.897 5.475 1.00 34.76 ? 12 LEU B CA 1 ATOM 3999 C C . LEU B 1 12 ? 16.078 -18.052 4.518 1.00 35.04 ? 12 LEU B C 1 ATOM 4000 O O . LEU B 1 12 ? 15.449 -17.844 3.482 1.00 35.14 ? 12 LEU B O 1 ATOM 4001 C CB . LEU B 1 12 ? 17.779 -16.321 5.216 1.00 34.28 ? 12 LEU B CB 1 ATOM 4002 C CG . LEU B 1 12 ? 18.035 -14.906 5.754 1.00 33.61 ? 12 LEU B CG 1 ATOM 4003 C CD1 . LEU B 1 12 ? 19.501 -14.491 5.586 1.00 31.76 ? 12 LEU B CD1 1 ATOM 4004 C CD2 . LEU B 1 12 ? 17.103 -13.874 5.108 1.00 30.71 ? 12 LEU B CD2 1 ATOM 4005 N N . LEU B 1 13 ? 16.508 -19.263 4.869 1.00 35.52 ? 13 LEU B N 1 ATOM 4006 C CA . LEU B 1 13 ? 16.220 -20.436 4.044 1.00 35.93 ? 13 LEU B CA 1 ATOM 4007 C C . LEU B 1 13 ? 14.730 -20.783 4.061 1.00 36.04 ? 13 LEU B C 1 ATOM 4008 O O . LEU B 1 13 ? 14.176 -21.176 3.033 1.00 36.04 ? 13 LEU B O 1 ATOM 4009 C CB . LEU B 1 13 ? 17.052 -21.651 4.471 1.00 36.01 ? 13 LEU B CB 1 ATOM 4010 C CG . LEU B 1 13 ? 16.852 -22.894 3.584 1.00 36.70 ? 13 LEU B CG 1 ATOM 4011 C CD1 . LEU B 1 13 ? 17.713 -22.844 2.319 1.00 36.54 ? 13 LEU B CD1 1 ATOM 4012 C CD2 . LEU B 1 13 ? 17.093 -24.179 4.361 1.00 36.84 ? 13 LEU B CD2 1 ATOM 4013 N N . LYS B 1 14 ? 14.087 -20.640 5.217 1.00 36.12 ? 14 LYS B N 1 ATOM 4014 C CA . LYS B 1 14 ? 12.652 -20.887 5.310 1.00 36.66 ? 14 LYS B CA 1 ATOM 4015 C C . LYS B 1 14 ? 11.869 -19.966 4.365 1.00 36.44 ? 14 LYS B C 1 ATOM 4016 O O . LYS B 1 14 ? 10.998 -20.423 3.621 1.00 36.52 ? 14 LYS B O 1 ATOM 4017 C CB . LYS B 1 14 ? 12.158 -20.730 6.746 1.00 36.98 ? 14 LYS B CB 1 ATOM 4018 C CG . LYS B 1 14 ? 10.885 -21.500 7.022 1.00 39.50 ? 14 LYS B CG 1 ATOM 4019 C CD . LYS B 1 14 ? 10.021 -20.815 8.069 1.00 43.83 ? 14 LYS B CD 1 ATOM 4020 C CE . LYS B 1 14 ? 9.967 -21.557 9.393 1.00 46.41 ? 14 LYS B CE 1 ATOM 4021 N NZ . LYS B 1 14 ? 9.044 -20.844 10.331 1.00 48.28 ? 14 LYS B NZ 1 ATOM 4022 N N . GLU B 1 15 ? 12.207 -18.677 4.378 1.00 36.10 ? 15 GLU B N 1 ATOM 4023 C CA . GLU B 1 15 ? 11.578 -17.702 3.497 1.00 35.82 ? 15 GLU B CA 1 ATOM 4024 C C . GLU B 1 15 ? 11.904 -17.926 2.018 1.00 35.81 ? 15 GLU B C 1 ATOM 4025 O O . GLU B 1 15 ? 11.069 -17.666 1.139 1.00 35.65 ? 15 GLU B O 1 ATOM 4026 C CB . GLU B 1 15 ? 11.931 -16.281 3.934 1.00 35.78 ? 15 GLU B CB 1 ATOM 4027 C CG . GLU B 1 15 ? 10.976 -15.756 4.992 1.00 36.21 ? 15 GLU B CG 1 ATOM 4028 C CD . GLU B 1 15 ? 11.421 -14.462 5.639 1.00 37.14 ? 15 GLU B CD 1 ATOM 4029 O OE1 . GLU B 1 15 ? 12.274 -13.752 5.056 1.00 37.61 ? 15 GLU B OE1 1 ATOM 4030 O OE2 . GLU B 1 15 ? 10.905 -14.158 6.741 1.00 36.97 ? 15 GLU B OE2 1 ATOM 4031 N N . LYS B 1 16 ? 13.110 -18.414 1.750 1.00 35.70 ? 16 LYS B N 1 ATOM 4032 C CA . LYS B 1 16 ? 13.499 -18.797 0.397 1.00 35.80 ? 16 LYS B CA 1 ATOM 4033 C C . LYS B 1 16 ? 12.614 -19.946 -0.080 1.00 35.91 ? 16 LYS B C 1 ATOM 4034 O O . LYS B 1 16 ? 12.183 -19.968 -1.233 1.00 35.66 ? 16 LYS B O 1 ATOM 4035 C CB . LYS B 1 16 ? 14.978 -19.195 0.358 1.00 35.69 ? 16 LYS B CB 1 ATOM 4036 C CG . LYS B 1 16 ? 15.585 -19.342 -1.035 1.00 35.19 ? 16 LYS B CG 1 ATOM 4037 C CD . LYS B 1 16 ? 16.947 -20.027 -0.917 1.00 36.18 ? 16 LYS B CD 1 ATOM 4038 C CE . LYS B 1 16 ? 17.779 -20.063 -2.203 1.00 36.47 ? 16 LYS B CE 1 ATOM 4039 N NZ . LYS B 1 16 ? 17.160 -19.449 -3.412 1.00 37.34 ? 16 LYS B NZ 1 ATOM 4040 N N . MET B 1 17 ? 12.317 -20.867 0.833 1.00 36.39 ? 17 MET B N 1 ATOM 4041 C CA . MET B 1 17 ? 11.533 -22.062 0.521 1.00 37.25 ? 17 MET B CA 1 ATOM 4042 C C . MET B 1 17 ? 10.027 -21.829 0.374 1.00 37.24 ? 17 MET B C 1 ATOM 4043 O O . MET B 1 17 ? 9.391 -22.451 -0.480 1.00 37.12 ? 17 MET B O 1 ATOM 4044 C CB . MET B 1 17 ? 11.799 -23.181 1.541 1.00 37.54 ? 17 MET B CB 1 ATOM 4045 C CG . MET B 1 17 ? 13.199 -23.816 1.468 1.00 39.19 ? 17 MET B CG 1 ATOM 4046 S SD . MET B 1 17 ? 13.707 -24.308 -0.202 1.00 43.82 ? 17 MET B SD 1 ATOM 4047 C CE . MET B 1 17 ? 14.887 -23.024 -0.646 1.00 41.16 ? 17 MET B CE 1 ATOM 4048 N N . MET B 1 18 ? 9.455 -20.950 1.194 1.00 37.38 ? 18 MET B N 1 ATOM 4049 C CA . MET B 1 18 ? 8.007 -20.767 1.156 1.00 37.63 ? 18 MET B CA 1 ATOM 4050 C C . MET B 1 18 ? 7.497 -19.699 0.176 1.00 37.45 ? 18 MET B C 1 ATOM 4051 O O . MET B 1 18 ? 6.306 -19.662 -0.122 1.00 37.55 ? 18 MET B O 1 ATOM 4052 C CB . MET B 1 18 ? 7.393 -20.634 2.560 1.00 37.92 ? 18 MET B CB 1 ATOM 4053 C CG . MET B 1 18 ? 7.832 -19.443 3.398 1.00 39.92 ? 18 MET B CG 1 ATOM 4054 S SD . MET B 1 18 ? 6.813 -19.309 4.894 1.00 44.03 ? 18 MET B SD 1 ATOM 4055 C CE . MET B 1 18 ? 7.872 -19.969 6.147 1.00 43.59 ? 18 MET B CE 1 ATOM 4056 N N . ARG B 1 19 ? 8.384 -18.862 -0.359 1.00 37.18 ? 19 ARG B N 1 ATOM 4057 C CA . ARG B 1 19 ? 7.941 -17.899 -1.364 1.00 37.09 ? 19 ARG B CA 1 ATOM 4058 C C . ARG B 1 19 ? 7.587 -18.617 -2.660 1.00 37.19 ? 19 ARG B C 1 ATOM 4059 O O . ARG B 1 19 ? 7.996 -19.757 -2.885 1.00 37.41 ? 19 ARG B O 1 ATOM 4060 C CB . ARG B 1 19 ? 8.948 -16.765 -1.597 1.00 36.94 ? 19 ARG B CB 1 ATOM 4061 C CG . ARG B 1 19 ? 10.129 -17.106 -2.466 1.00 36.98 ? 19 ARG B CG 1 ATOM 4062 C CD . ARG B 1 19 ? 10.930 -15.875 -2.804 1.00 37.64 ? 19 ARG B CD 1 ATOM 4063 N NE . ARG B 1 19 ? 11.488 -15.215 -1.617 1.00 39.48 ? 19 ARG B NE 1 ATOM 4064 C CZ . ARG B 1 19 ? 12.742 -15.353 -1.179 1.00 39.88 ? 19 ARG B CZ 1 ATOM 4065 N NH1 . ARG B 1 19 ? 13.605 -16.141 -1.821 1.00 39.72 ? 19 ARG B NH1 1 ATOM 4066 N NH2 . ARG B 1 19 ? 13.135 -14.694 -0.094 1.00 38.09 ? 19 ARG B NH2 1 ATOM 4067 N N . LEU B 1 20 ? 6.814 -17.942 -3.500 1.00 37.04 ? 20 LEU B N 1 ATOM 4068 C CA . LEU B 1 20 ? 6.254 -18.542 -4.691 1.00 36.88 ? 20 LEU B CA 1 ATOM 4069 C C . LEU B 1 20 ? 7.345 -19.132 -5.575 1.00 36.79 ? 20 LEU B C 1 ATOM 4070 O O . LEU B 1 20 ? 8.292 -18.435 -5.955 1.00 36.62 ? 20 LEU B O 1 ATOM 4071 C CB . LEU B 1 20 ? 5.409 -17.505 -5.433 1.00 36.96 ? 20 LEU B CB 1 ATOM 4072 C CG . LEU B 1 20 ? 4.503 -17.993 -6.559 1.00 37.12 ? 20 LEU B CG 1 ATOM 4073 C CD1 . LEU B 1 20 ? 3.121 -17.397 -6.426 1.00 36.96 ? 20 LEU B CD1 1 ATOM 4074 C CD2 . LEU B 1 20 ? 5.126 -17.631 -7.888 1.00 37.78 ? 20 LEU B CD2 1 ATOM 4075 N N . GLY B 1 21 ? 7.214 -20.428 -5.863 1.00 36.79 ? 21 GLY B N 1 ATOM 4076 C CA . GLY B 1 21 ? 8.165 -21.159 -6.710 1.00 36.88 ? 21 GLY B CA 1 ATOM 4077 C C . GLY B 1 21 ? 9.444 -21.610 -6.018 1.00 37.09 ? 21 GLY B C 1 ATOM 4078 O O . GLY B 1 21 ? 10.298 -22.259 -6.632 1.00 37.06 ? 21 GLY B O 1 ATOM 4079 N N . GLY B 1 22 ? 9.565 -21.283 -4.734 1.00 37.22 ? 22 GLY B N 1 ATOM 4080 C CA . GLY B 1 22 ? 10.786 -21.527 -3.967 1.00 37.75 ? 22 GLY B CA 1 ATOM 4081 C C . GLY B 1 22 ? 11.262 -22.971 -3.854 1.00 37.98 ? 22 GLY B C 1 ATOM 4082 O O . GLY B 1 22 ? 12.420 -23.214 -3.503 1.00 37.89 ? 22 GLY B O 1 ATOM 4083 N N . ARG B 1 23 ? 10.381 -23.925 -4.142 1.00 38.25 ? 23 ARG B N 1 ATOM 4084 C CA . ARG B 1 23 ? 10.748 -25.341 -4.057 1.00 38.74 ? 23 ARG B CA 1 ATOM 4085 C C . ARG B 1 23 ? 10.944 -26.017 -5.412 1.00 38.19 ? 23 ARG B C 1 ATOM 4086 O O . ARG B 1 23 ? 11.299 -27.189 -5.474 1.00 38.41 ? 23 ARG B O 1 ATOM 4087 C CB . ARG B 1 23 ? 9.754 -26.102 -3.185 1.00 39.17 ? 23 ARG B CB 1 ATOM 4088 C CG . ARG B 1 23 ? 9.856 -25.647 -1.762 1.00 41.96 ? 23 ARG B CG 1 ATOM 4089 C CD . ARG B 1 23 ? 9.068 -26.467 -0.788 1.00 47.18 ? 23 ARG B CD 1 ATOM 4090 N NE . ARG B 1 23 ? 9.530 -26.114 0.550 1.00 52.72 ? 23 ARG B NE 1 ATOM 4091 C CZ . ARG B 1 23 ? 9.098 -26.655 1.684 1.00 56.04 ? 23 ARG B CZ 1 ATOM 4092 N NH1 . ARG B 1 23 ? 8.160 -27.598 1.674 1.00 57.74 ? 23 ARG B NH1 1 ATOM 4093 N NH2 . ARG B 1 23 ? 9.610 -26.245 2.841 1.00 57.51 ? 23 ARG B NH2 1 ATOM 4094 N N . LEU B 1 24 ? 10.727 -25.269 -6.489 1.00 37.59 ? 24 LEU B N 1 ATOM 4095 C CA . LEU B 1 24 ? 11.011 -25.760 -7.826 1.00 37.06 ? 24 LEU B CA 1 ATOM 4096 C C . LEU B 1 24 ? 12.502 -26.044 -7.948 1.00 37.03 ? 24 LEU B C 1 ATOM 4097 O O . LEU B 1 24 ? 13.338 -25.226 -7.536 1.00 36.85 ? 24 LEU B O 1 ATOM 4098 C CB . LEU B 1 24 ? 10.570 -24.752 -8.899 1.00 36.67 ? 24 LEU B CB 1 ATOM 4099 C CG . LEU B 1 24 ? 9.073 -24.467 -9.079 1.00 36.20 ? 24 LEU B CG 1 ATOM 4100 C CD1 . LEU B 1 24 ? 8.855 -23.530 -10.263 1.00 35.69 ? 24 LEU B CD1 1 ATOM 4101 C CD2 . LEU B 1 24 ? 8.243 -25.747 -9.242 1.00 34.80 ? 24 LEU B CD2 1 ATOM 4102 N N . VAL B 1 25 ? 12.821 -27.220 -8.491 1.00 37.03 ? 25 VAL B N 1 ATOM 4103 C CA . VAL B 1 25 ? 14.207 -27.618 -8.735 1.00 36.67 ? 25 VAL B CA 1 ATOM 4104 C C . VAL B 1 25 ? 14.615 -27.142 -10.125 1.00 36.70 ? 25 VAL B C 1 ATOM 4105 O O . VAL B 1 25 ? 13.969 -27.468 -11.108 1.00 36.89 ? 25 VAL B O 1 ATOM 4106 C CB . VAL B 1 25 ? 14.414 -29.156 -8.589 1.00 36.55 ? 25 VAL B CB 1 ATOM 4107 C CG1 . VAL B 1 25 ? 15.832 -29.543 -8.976 1.00 36.02 ? 25 VAL B CG1 1 ATOM 4108 C CG2 . VAL B 1 25 ? 14.112 -29.617 -7.161 1.00 36.05 ? 25 VAL B CG2 1 ATOM 4109 N N . LEU B 1 26 ? 15.672 -26.345 -10.188 1.00 36.86 ? 26 LEU B N 1 ATOM 4110 C CA . LEU B 1 26 ? 16.245 -25.892 -11.452 1.00 37.19 ? 26 LEU B CA 1 ATOM 4111 C C . LEU B 1 26 ? 17.345 -26.837 -11.946 1.00 37.58 ? 26 LEU B C 1 ATOM 4112 O O . LEU B 1 26 ? 18.122 -27.364 -11.145 1.00 37.80 ? 26 LEU B O 1 ATOM 4113 C CB . LEU B 1 26 ? 16.828 -24.487 -11.270 1.00 36.90 ? 26 LEU B CB 1 ATOM 4114 C CG . LEU B 1 26 ? 16.120 -23.255 -11.844 1.00 36.35 ? 26 LEU B CG 1 ATOM 4115 C CD1 . LEU B 1 26 ? 14.597 -23.342 -11.789 1.00 34.90 ? 26 LEU B CD1 1 ATOM 4116 C CD2 . LEU B 1 26 ? 16.634 -22.007 -11.147 1.00 35.44 ? 26 LEU B CD2 1 ATOM 4117 N N . ASN B 1 27 ? 17.407 -27.053 -13.259 1.00 37.88 ? 27 ASN B N 1 ATOM 4118 C CA . ASN B 1 27 ? 18.539 -27.771 -13.859 1.00 38.13 ? 27 ASN B CA 1 ATOM 4119 C C . ASN B 1 27 ? 19.682 -26.790 -14.133 1.00 38.61 ? 27 ASN B C 1 ATOM 4120 O O . ASN B 1 27 ? 19.500 -25.569 -14.008 1.00 38.96 ? 27 ASN B O 1 ATOM 4121 C CB . ASN B 1 27 ? 18.126 -28.533 -15.127 1.00 37.89 ? 27 ASN B CB 1 ATOM 4122 C CG . ASN B 1 27 ? 17.809 -27.619 -16.295 1.00 37.39 ? 27 ASN B CG 1 ATOM 4123 O OD1 . ASN B 1 27 ? 18.476 -26.613 -16.515 1.00 36.91 ? 27 ASN B OD1 1 ATOM 4124 N ND2 . ASN B 1 27 ? 16.789 -27.977 -17.062 1.00 36.95 ? 27 ASN B ND2 1 ATOM 4125 N N . THR B 1 28 ? 20.846 -27.307 -14.521 1.00 38.86 ? 28 THR B N 1 ATOM 4126 C CA . THR B 1 28 ? 22.059 -26.485 -14.551 1.00 38.93 ? 28 THR B CA 1 ATOM 4127 C C . THR B 1 28 ? 21.974 -25.386 -15.608 1.00 38.91 ? 28 THR B C 1 ATOM 4128 O O . THR B 1 28 ? 22.562 -24.316 -15.459 1.00 38.84 ? 28 THR B O 1 ATOM 4129 C CB . THR B 1 28 ? 23.359 -27.334 -14.719 1.00 39.12 ? 28 THR B CB 1 ATOM 4130 O OG1 . THR B 1 28 ? 23.753 -27.362 -16.097 1.00 39.75 ? 28 THR B OG1 1 ATOM 4131 C CG2 . THR B 1 28 ? 23.183 -28.766 -14.183 1.00 38.48 ? 28 THR B CG2 1 ATOM 4132 N N . LYS B 1 29 ? 21.223 -25.661 -16.667 1.00 39.24 ? 29 LYS B N 1 ATOM 4133 C CA . LYS B 1 29 ? 20.947 -24.688 -17.724 1.00 39.69 ? 29 LYS B CA 1 ATOM 4134 C C . LYS B 1 29 ? 20.104 -23.526 -17.172 1.00 39.41 ? 29 LYS B C 1 ATOM 4135 O O . LYS B 1 29 ? 20.390 -22.347 -17.432 1.00 39.20 ? 29 LYS B O 1 ATOM 4136 C CB . LYS B 1 29 ? 20.188 -25.379 -18.855 1.00 40.05 ? 29 LYS B CB 1 ATOM 4137 C CG . LYS B 1 29 ? 20.486 -24.875 -20.246 1.00 42.54 ? 29 LYS B CG 1 ATOM 4138 C CD . LYS B 1 29 ? 21.546 -25.744 -20.900 1.00 47.36 ? 29 LYS B CD 1 ATOM 4139 C CE . LYS B 1 29 ? 21.403 -25.738 -22.415 1.00 50.34 ? 29 LYS B CE 1 ATOM 4140 N NZ . LYS B 1 29 ? 22.566 -26.418 -23.057 1.00 52.33 ? 29 LYS B NZ 1 ATOM 4141 N N . GLU B 1 30 ? 19.067 -23.879 -16.410 1.00 39.04 ? 30 GLU B N 1 ATOM 4142 C CA . GLU B 1 30 ? 18.169 -22.909 -15.791 1.00 38.84 ? 30 GLU B CA 1 ATOM 4143 C C . GLU B 1 30 ? 18.873 -22.091 -14.706 1.00 38.95 ? 30 GLU B C 1 ATOM 4144 O O . GLU B 1 30 ? 18.626 -20.884 -14.574 1.00 38.75 ? 30 GLU B O 1 ATOM 4145 C CB . GLU B 1 30 ? 16.951 -23.615 -15.196 1.00 38.63 ? 30 GLU B CB 1 ATOM 4146 C CG . GLU B 1 30 ? 15.963 -24.146 -16.212 1.00 38.13 ? 30 GLU B CG 1 ATOM 4147 C CD . GLU B 1 30 ? 14.997 -25.143 -15.595 1.00 38.30 ? 30 GLU B CD 1 ATOM 4148 O OE1 . GLU B 1 30 ? 15.439 -25.983 -14.776 1.00 38.21 ? 30 GLU B OE1 1 ATOM 4149 O OE2 . GLU B 1 30 ? 13.792 -25.086 -15.929 1.00 38.34 ? 30 GLU B OE2 1 ATOM 4150 N N . GLU B 1 31 ? 19.738 -22.754 -13.933 1.00 38.91 ? 31 GLU B N 1 ATOM 4151 C CA . GLU B 1 31 ? 20.578 -22.081 -12.937 1.00 39.06 ? 31 GLU B CA 1 ATOM 4152 C C . GLU B 1 31 ? 21.440 -21.009 -13.590 1.00 38.61 ? 31 GLU B C 1 ATOM 4153 O O . GLU B 1 31 ? 21.630 -19.929 -13.031 1.00 38.66 ? 31 GLU B O 1 ATOM 4154 C CB . GLU B 1 31 ? 21.464 -23.087 -12.198 1.00 39.18 ? 31 GLU B CB 1 ATOM 4155 C CG . GLU B 1 31 ? 20.726 -23.927 -11.170 1.00 41.41 ? 31 GLU B CG 1 ATOM 4156 C CD . GLU B 1 31 ? 20.471 -23.191 -9.855 1.00 44.77 ? 31 GLU B CD 1 ATOM 4157 O OE1 . GLU B 1 31 ? 20.418 -21.935 -9.853 1.00 46.42 ? 31 GLU B OE1 1 ATOM 4158 O OE2 . GLU B 1 31 ? 20.322 -23.877 -8.814 1.00 45.58 ? 31 GLU B OE2 1 ATOM 4159 N N . LEU B 1 32 ? 21.946 -21.318 -14.779 1.00 38.31 ? 32 LEU B N 1 ATOM 4160 C CA . LEU B 1 32 ? 22.778 -20.396 -15.538 1.00 38.20 ? 32 LEU B CA 1 ATOM 4161 C C . LEU B 1 32 ? 21.972 -19.198 -16.052 1.00 37.70 ? 32 LEU B C 1 ATOM 4162 O O . LEU B 1 32 ? 22.437 -18.058 -15.965 1.00 37.63 ? 32 LEU B O 1 ATOM 4163 C CB . LEU B 1 32 ? 23.464 -21.130 -16.698 1.00 38.34 ? 32 LEU B CB 1 ATOM 4164 C CG . LEU B 1 32 ? 24.864 -20.675 -17.123 1.00 39.41 ? 32 LEU B CG 1 ATOM 4165 C CD1 . LEU B 1 32 ? 24.869 -19.324 -17.849 1.00 40.66 ? 32 LEU B CD1 1 ATOM 4166 C CD2 . LEU B 1 32 ? 25.828 -20.666 -15.932 1.00 40.53 ? 32 LEU B CD2 1 ATOM 4167 N N . ALA B 1 33 ? 20.778 -19.464 -16.587 1.00 37.10 ? 33 ALA B N 1 ATOM 4168 C CA . ALA B 1 33 ? 19.857 -18.409 -17.020 1.00 36.62 ? 33 ALA B CA 1 ATOM 4169 C C . ALA B 1 33 ? 19.414 -17.542 -15.837 1.00 36.41 ? 33 ALA B C 1 ATOM 4170 O O . ALA B 1 33 ? 19.324 -16.317 -15.952 1.00 36.30 ? 33 ALA B O 1 ATOM 4171 C CB . ALA B 1 33 ? 18.640 -19.009 -17.726 1.00 36.71 ? 33 ALA B CB 1 ATOM 4172 N N . ASN B 1 34 ? 19.146 -18.179 -14.701 1.00 35.87 ? 34 ASN B N 1 ATOM 4173 C CA . ASN B 1 34 ? 18.778 -17.453 -13.499 1.00 35.66 ? 34 ASN B CA 1 ATOM 4174 C C . ASN B 1 34 ? 19.887 -16.520 -13.040 1.00 35.90 ? 34 ASN B C 1 ATOM 4175 O O . ASN B 1 34 ? 19.627 -15.380 -12.662 1.00 35.89 ? 34 ASN B O 1 ATOM 4176 C CB . ASN B 1 34 ? 18.411 -18.417 -12.372 1.00 35.47 ? 34 ASN B CB 1 ATOM 4177 C CG . ASN B 1 34 ? 18.022 -17.696 -11.095 1.00 34.52 ? 34 ASN B CG 1 ATOM 4178 O OD1 . ASN B 1 34 ? 18.690 -17.829 -10.075 1.00 34.44 ? 34 ASN B OD1 1 ATOM 4179 N ND2 . ASN B 1 34 ? 16.954 -16.915 -11.154 1.00 31.51 ? 34 ASN B ND2 1 ATOM 4180 N N . GLU B 1 35 ? 21.123 -17.011 -13.086 1.00 36.23 ? 35 GLU B N 1 ATOM 4181 C CA . GLU B 1 35 ? 22.289 -16.227 -12.689 1.00 36.61 ? 35 GLU B CA 1 ATOM 4182 C C . GLU B 1 35 ? 22.457 -14.971 -13.546 1.00 36.06 ? 35 GLU B C 1 ATOM 4183 O O . GLU B 1 35 ? 22.765 -13.896 -13.030 1.00 36.07 ? 35 GLU B O 1 ATOM 4184 C CB . GLU B 1 35 ? 23.547 -17.084 -12.756 1.00 36.90 ? 35 GLU B CB 1 ATOM 4185 C CG . GLU B 1 35 ? 24.699 -16.541 -11.937 1.00 40.20 ? 35 GLU B CG 1 ATOM 4186 C CD . GLU B 1 35 ? 26.029 -17.191 -12.296 1.00 43.92 ? 35 GLU B CD 1 ATOM 4187 O OE1 . GLU B 1 35 ? 26.547 -16.893 -13.391 1.00 45.23 ? 35 GLU B OE1 1 ATOM 4188 O OE2 . GLU B 1 35 ? 26.556 -17.985 -11.481 1.00 45.43 ? 35 GLU B OE2 1 ATOM 4189 N N . ARG B 1 36 ? 22.246 -15.109 -14.851 1.00 35.58 ? 36 ARG B N 1 ATOM 4190 C CA . ARG B 1 36 ? 22.351 -13.967 -15.761 1.00 35.50 ? 36 ARG B CA 1 ATOM 4191 C C . ARG B 1 36 ? 21.146 -13.029 -15.611 1.00 34.56 ? 36 ARG B C 1 ATOM 4192 O O . ARG B 1 36 ? 21.310 -11.806 -15.563 1.00 34.46 ? 36 ARG B O 1 ATOM 4193 C CB . ARG B 1 36 ? 22.576 -14.426 -17.213 1.00 35.83 ? 36 ARG B CB 1 ATOM 4194 C CG . ARG B 1 36 ? 23.808 -15.341 -17.360 1.00 38.09 ? 36 ARG B CG 1 ATOM 4195 C CD . ARG B 1 36 ? 24.234 -15.537 -18.797 1.00 42.22 ? 36 ARG B CD 1 ATOM 4196 N NE . ARG B 1 36 ? 24.903 -14.350 -19.327 1.00 45.93 ? 36 ARG B NE 1 ATOM 4197 C CZ . ARG B 1 36 ? 24.991 -14.042 -20.620 1.00 47.50 ? 36 ARG B CZ 1 ATOM 4198 N NH1 . ARG B 1 36 ? 24.447 -14.836 -21.536 1.00 47.77 ? 36 ARG B NH1 1 ATOM 4199 N NH2 . ARG B 1 36 ? 25.615 -12.932 -20.998 1.00 47.91 ? 36 ARG B NH2 1 ATOM 4200 N N . LEU B 1 37 ? 19.950 -13.606 -15.495 1.00 33.57 ? 37 LEU B N 1 ATOM 4201 C CA . LEU B 1 37 ? 18.741 -12.840 -15.161 1.00 32.60 ? 37 LEU B CA 1 ATOM 4202 C C . LEU B 1 37 ? 18.864 -12.043 -13.847 1.00 32.15 ? 37 LEU B C 1 ATOM 4203 O O . LEU B 1 37 ? 18.622 -10.832 -13.834 1.00 31.77 ? 37 LEU B O 1 ATOM 4204 C CB . LEU B 1 37 ? 17.506 -13.746 -15.134 1.00 32.48 ? 37 LEU B CB 1 ATOM 4205 C CG . LEU B 1 37 ? 16.146 -13.161 -14.723 1.00 31.95 ? 37 LEU B CG 1 ATOM 4206 C CD1 . LEU B 1 37 ? 15.625 -12.124 -15.718 1.00 30.37 ? 37 LEU B CD1 1 ATOM 4207 C CD2 . LEU B 1 37 ? 15.145 -14.284 -14.538 1.00 31.35 ? 37 LEU B CD2 1 ATOM 4208 N N . MET B 1 38 ? 19.252 -12.713 -12.759 1.00 31.69 ? 38 MET B N 1 ATOM 4209 C CA . MET B 1 38 ? 19.397 -12.043 -11.457 1.00 31.50 ? 38 MET B CA 1 ATOM 4210 C C . MET B 1 38 ? 20.444 -10.933 -11.446 1.00 31.05 ? 38 MET B C 1 ATOM 4211 O O . MET B 1 38 ? 20.237 -9.902 -10.810 1.00 30.97 ? 38 MET B O 1 ATOM 4212 C CB . MET B 1 38 ? 19.646 -13.042 -10.320 1.00 31.48 ? 38 MET B CB 1 ATOM 4213 C CG . MET B 1 38 ? 18.446 -13.924 -9.964 1.00 32.57 ? 38 MET B CG 1 ATOM 4214 S SD . MET B 1 38 ? 16.924 -13.048 -9.520 1.00 33.56 ? 38 MET B SD 1 ATOM 4215 C CE . MET B 1 38 ? 16.250 -12.725 -11.129 1.00 35.64 ? 38 MET B CE 1 ATOM 4216 N N . THR B 1 39 ? 21.559 -11.141 -12.145 1.00 30.92 ? 39 THR B N 1 ATOM 4217 C CA . THR B 1 39 ? 22.579 -10.097 -12.302 1.00 30.50 ? 39 THR B CA 1 ATOM 4218 C C . THR B 1 39 ? 21.970 -8.841 -12.916 1.00 30.47 ? 39 THR B C 1 ATOM 4219 O O . THR B 1 39 ? 22.184 -7.735 -12.418 1.00 30.85 ? 39 THR B O 1 ATOM 4220 C CB . THR B 1 39 ? 23.763 -10.583 -13.172 1.00 30.54 ? 39 THR B CB 1 ATOM 4221 O OG1 . THR B 1 39 ? 24.429 -11.654 -12.502 1.00 30.36 ? 39 THR B OG1 1 ATOM 4222 C CG2 . THR B 1 39 ? 24.761 -9.448 -13.453 1.00 29.77 ? 39 THR B CG2 1 ATOM 4223 N N . LEU B 1 40 ? 21.208 -9.014 -13.993 1.00 30.24 ? 40 LEU B N 1 ATOM 4224 C CA . LEU B 1 40 ? 20.549 -7.888 -14.664 1.00 30.09 ? 40 LEU B CA 1 ATOM 4225 C C . LEU B 1 40 ? 19.490 -7.217 -13.784 1.00 29.76 ? 40 LEU B C 1 ATOM 4226 O O . LEU B 1 40 ? 19.346 -5.990 -13.801 1.00 29.66 ? 40 LEU B O 1 ATOM 4227 C CB . LEU B 1 40 ? 19.952 -8.331 -16.000 1.00 30.13 ? 40 LEU B CB 1 ATOM 4228 C CG . LEU B 1 40 ? 20.973 -8.771 -17.060 1.00 30.67 ? 40 LEU B CG 1 ATOM 4229 C CD1 . LEU B 1 40 ? 20.314 -9.632 -18.113 1.00 30.61 ? 40 LEU B CD1 1 ATOM 4230 C CD2 . LEU B 1 40 ? 21.709 -7.583 -17.705 1.00 30.52 ? 40 LEU B CD2 1 ATOM 4231 N N . LYS B 1 41 ? 18.774 -8.029 -13.008 1.00 29.43 ? 41 LYS B N 1 ATOM 4232 C CA . LYS B 1 41 ? 17.783 -7.535 -12.058 1.00 29.15 ? 41 LYS B CA 1 ATOM 4233 C C . LYS B 1 41 ? 18.425 -6.699 -10.944 1.00 29.44 ? 41 LYS B C 1 ATOM 4234 O O . LYS B 1 41 ? 18.060 -5.535 -10.747 1.00 29.51 ? 41 LYS B O 1 ATOM 4235 C CB . LYS B 1 41 ? 16.979 -8.694 -11.478 1.00 28.75 ? 41 LYS B CB 1 ATOM 4236 C CG . LYS B 1 41 ? 15.932 -8.261 -10.471 1.00 28.19 ? 41 LYS B CG 1 ATOM 4237 C CD . LYS B 1 41 ? 15.012 -9.390 -10.075 1.00 26.00 ? 41 LYS B CD 1 ATOM 4238 C CE . LYS B 1 41 ? 14.096 -8.952 -8.965 1.00 25.63 ? 41 LYS B CE 1 ATOM 4239 N NZ . LYS B 1 41 ? 13.025 -9.942 -8.743 1.00 27.13 ? 41 LYS B NZ 1 ATOM 4240 N N . ILE B 1 42 ? 19.387 -7.293 -10.240 1.00 29.56 ? 42 ILE B N 1 ATOM 4241 C CA . ILE B 1 42 ? 20.093 -6.633 -9.149 1.00 29.91 ? 42 ILE B CA 1 ATOM 4242 C C . ILE B 1 42 ? 20.714 -5.290 -9.571 1.00 30.67 ? 42 ILE B C 1 ATOM 4243 O O . ILE B 1 42 ? 20.512 -4.273 -8.898 1.00 31.07 ? 42 ILE B O 1 ATOM 4244 C CB . ILE B 1 42 ? 21.129 -7.591 -8.509 1.00 29.93 ? 42 ILE B CB 1 ATOM 4245 C CG1 . ILE B 1 42 ? 20.403 -8.637 -7.656 1.00 29.28 ? 42 ILE B CG1 1 ATOM 4246 C CG2 . ILE B 1 42 ? 22.168 -6.828 -7.669 1.00 29.72 ? 42 ILE B CG2 1 ATOM 4247 C CD1 . ILE B 1 42 ? 21.188 -9.906 -7.427 1.00 28.21 ? 42 ILE B CD1 1 ATOM 4248 N N . ALA B 1 43 ? 21.443 -5.281 -10.687 1.00 31.05 ? 43 ALA B N 1 ATOM 4249 C CA . ALA B 1 43 ? 22.023 -4.050 -11.226 1.00 31.73 ? 43 ALA B CA 1 ATOM 4250 C C . ALA B 1 43 ? 20.973 -2.952 -11.433 1.00 32.31 ? 43 ALA B C 1 ATOM 4251 O O . ALA B 1 43 ? 21.198 -1.781 -11.104 1.00 32.24 ? 43 ALA B O 1 ATOM 4252 C CB . ALA B 1 43 ? 22.754 -4.334 -12.541 1.00 31.32 ? 43 ALA B CB 1 ATOM 4253 N N . GLU B 1 44 ? 19.830 -3.343 -11.984 1.00 33.14 ? 44 GLU B N 1 ATOM 4254 C CA . GLU B 1 44 ? 18.760 -2.408 -12.277 1.00 34.18 ? 44 GLU B CA 1 ATOM 4255 C C . GLU B 1 44 ? 18.165 -1.860 -10.976 1.00 34.70 ? 44 GLU B C 1 ATOM 4256 O O . GLU B 1 44 ? 17.848 -0.674 -10.882 1.00 34.62 ? 44 GLU B O 1 ATOM 4257 C CB . GLU B 1 44 ? 17.691 -3.116 -13.091 1.00 34.21 ? 44 GLU B CB 1 ATOM 4258 C CG . GLU B 1 44 ? 17.374 -2.454 -14.389 1.00 35.59 ? 44 GLU B CG 1 ATOM 4259 C CD . GLU B 1 44 ? 16.485 -3.314 -15.262 1.00 37.33 ? 44 GLU B CD 1 ATOM 4260 O OE1 . GLU B 1 44 ? 17.027 -4.131 -16.043 1.00 37.16 ? 44 GLU B OE1 1 ATOM 4261 O OE2 . GLU B 1 44 ? 15.246 -3.166 -15.162 1.00 38.58 ? 44 GLU B OE2 1 ATOM 4262 N N . MET B 1 45 ? 18.031 -2.728 -9.975 1.00 35.50 ? 45 MET B N 1 ATOM 4263 C CA . MET B 1 45 ? 17.532 -2.320 -8.666 1.00 36.69 ? 45 MET B CA 1 ATOM 4264 C C . MET B 1 45 ? 18.506 -1.446 -7.868 1.00 36.63 ? 45 MET B C 1 ATOM 4265 O O . MET B 1 45 ? 18.077 -0.488 -7.220 1.00 36.41 ? 45 MET B O 1 ATOM 4266 C CB . MET B 1 45 ? 17.056 -3.531 -7.859 1.00 37.20 ? 45 MET B CB 1 ATOM 4267 C CG . MET B 1 45 ? 15.643 -3.942 -8.246 1.00 39.77 ? 45 MET B CG 1 ATOM 4268 S SD . MET B 1 45 ? 14.920 -5.244 -7.235 1.00 46.81 ? 45 MET B SD 1 ATOM 4269 C CE . MET B 1 45 ? 14.204 -4.288 -5.905 1.00 45.14 ? 45 MET B CE 1 ATOM 4270 N N . LYS B 1 46 ? 19.800 -1.761 -7.936 1.00 36.76 ? 46 LYS B N 1 ATOM 4271 C CA . LYS B 1 46 ? 20.843 -0.909 -7.358 1.00 37.04 ? 46 LYS B CA 1 ATOM 4272 C C . LYS B 1 46 ? 20.745 0.526 -7.866 1.00 36.63 ? 46 LYS B C 1 ATOM 4273 O O . LYS B 1 46 ? 20.745 1.481 -7.080 1.00 36.54 ? 46 LYS B O 1 ATOM 4274 C CB . LYS B 1 46 ? 22.234 -1.480 -7.653 1.00 37.44 ? 46 LYS B CB 1 ATOM 4275 C CG . LYS B 1 46 ? 22.923 -2.126 -6.448 1.00 39.45 ? 46 LYS B CG 1 ATOM 4276 C CD . LYS B 1 46 ? 22.072 -3.196 -5.772 1.00 42.01 ? 46 LYS B CD 1 ATOM 4277 C CE . LYS B 1 46 ? 22.279 -3.158 -4.264 1.00 43.37 ? 46 LYS B CE 1 ATOM 4278 N NZ . LYS B 1 46 ? 22.599 -4.507 -3.709 1.00 44.20 ? 46 LYS B NZ 1 ATOM 4279 N N . GLU B 1 47 ? 20.638 0.662 -9.182 1.00 35.97 ? 47 GLU B N 1 ATOM 4280 C CA . GLU B 1 47 ? 20.512 1.960 -9.827 1.00 35.66 ? 47 GLU B CA 1 ATOM 4281 C C . GLU B 1 47 ? 19.238 2.702 -9.400 1.00 35.17 ? 47 GLU B C 1 ATOM 4282 O O . GLU B 1 47 ? 19.263 3.918 -9.180 1.00 35.13 ? 47 GLU B O 1 ATOM 4283 C CB . GLU B 1 47 ? 20.600 1.796 -11.353 1.00 35.71 ? 47 GLU B CB 1 ATOM 4284 C CG . GLU B 1 47 ? 20.482 3.080 -12.165 1.00 36.59 ? 47 GLU B CG 1 ATOM 4285 C CD . GLU B 1 47 ? 21.629 4.068 -11.965 1.00 38.01 ? 47 GLU B CD 1 ATOM 4286 O OE1 . GLU B 1 47 ? 22.597 3.780 -11.231 1.00 37.79 ? 47 GLU B OE1 1 ATOM 4287 O OE2 . GLU B 1 47 ? 21.553 5.160 -12.561 1.00 40.12 ? 47 GLU B OE2 1 ATOM 4288 N N . ALA B 1 48 ? 18.135 1.966 -9.269 1.00 34.75 ? 48 ALA B N 1 ATOM 4289 C CA . ALA B 1 48 ? 16.863 2.551 -8.812 1.00 34.48 ? 48 ALA B CA 1 ATOM 4290 C C . ALA B 1 48 ? 16.899 2.955 -7.333 1.00 34.27 ? 48 ALA B C 1 ATOM 4291 O O . ALA B 1 48 ? 16.264 3.931 -6.934 1.00 34.03 ? 48 ALA B O 1 ATOM 4292 C CB . ALA B 1 48 ? 15.700 1.625 -9.090 1.00 34.16 ? 48 ALA B CB 1 ATOM 4293 N N . MET B 1 49 ? 17.652 2.205 -6.535 1.00 34.26 ? 49 MET B N 1 ATOM 4294 C CA . MET B 1 49 ? 17.930 2.584 -5.151 1.00 34.27 ? 49 MET B CA 1 ATOM 4295 C C . MET B 1 49 ? 18.798 3.841 -5.068 1.00 34.43 ? 49 MET B C 1 ATOM 4296 O O . MET B 1 49 ? 18.647 4.630 -4.149 1.00 34.74 ? 49 MET B O 1 ATOM 4297 C CB . MET B 1 49 ? 18.572 1.421 -4.384 1.00 34.03 ? 49 MET B CB 1 ATOM 4298 C CG . MET B 1 49 ? 17.587 0.327 -4.057 1.00 34.00 ? 49 MET B CG 1 ATOM 4299 S SD . MET B 1 49 ? 18.304 -1.262 -3.650 1.00 34.83 ? 49 MET B SD 1 ATOM 4300 C CE . MET B 1 49 ? 18.249 -1.222 -1.864 1.00 34.46 ? 49 MET B CE 1 ATOM 4301 N N . ARG B 1 50 ? 19.690 4.032 -6.037 1.00 34.66 ? 50 ARG B N 1 ATOM 4302 C CA . ARG B 1 50 ? 20.520 5.230 -6.089 1.00 34.66 ? 50 ARG B CA 1 ATOM 4303 C C . ARG B 1 50 ? 19.711 6.466 -6.496 1.00 34.65 ? 50 ARG B C 1 ATOM 4304 O O . ARG B 1 50 ? 19.737 7.478 -5.796 1.00 34.84 ? 50 ARG B O 1 ATOM 4305 C CB . ARG B 1 50 ? 21.699 5.028 -7.046 1.00 34.80 ? 50 ARG B CB 1 ATOM 4306 C CG . ARG B 1 50 ? 22.662 6.208 -7.117 1.00 35.58 ? 50 ARG B CG 1 ATOM 4307 C CD . ARG B 1 50 ? 23.853 5.904 -8.023 1.00 37.45 ? 50 ARG B CD 1 ATOM 4308 N NE . ARG B 1 50 ? 23.511 5.980 -9.447 1.00 39.10 ? 50 ARG B NE 1 ATOM 4309 C CZ . ARG B 1 50 ? 23.443 7.112 -10.151 1.00 39.63 ? 50 ARG B CZ 1 ATOM 4310 N NH1 . ARG B 1 50 ? 23.686 8.283 -9.567 1.00 39.83 ? 50 ARG B NH1 1 ATOM 4311 N NH2 . ARG B 1 50 ? 23.122 7.075 -11.440 1.00 38.41 ? 50 ARG B NH2 1 ATOM 4312 N N . THR B 1 51 ? 19.000 6.380 -7.623 1.00 34.20 ? 51 THR B N 1 ATOM 4313 C CA . THR B 1 51 ? 18.314 7.545 -8.204 1.00 33.52 ? 51 THR B CA 1 ATOM 4314 C C . THR B 1 51 ? 16.877 7.722 -7.725 1.00 32.96 ? 51 THR B C 1 ATOM 4315 O O . THR B 1 51 ? 16.308 8.802 -7.869 1.00 33.00 ? 51 THR B O 1 ATOM 4316 C CB . THR B 1 51 ? 18.277 7.482 -9.759 1.00 33.85 ? 51 THR B CB 1 ATOM 4317 O OG1 . THR B 1 51 ? 17.466 6.374 -10.186 1.00 33.53 ? 51 THR B OG1 1 ATOM 4318 C CG2 . THR B 1 51 ? 19.696 7.366 -10.351 1.00 33.53 ? 51 THR B CG2 1 ATOM 4319 N N . LEU B 1 52 ? 16.301 6.654 -7.169 1.00 32.20 ? 52 LEU B N 1 ATOM 4320 C CA . LEU B 1 52 ? 14.865 6.562 -6.843 1.00 31.13 ? 52 LEU B CA 1 ATOM 4321 C C . LEU B 1 52 ? 13.944 6.578 -8.071 1.00 30.70 ? 52 LEU B C 1 ATOM 4322 O O . LEU B 1 52 ? 12.723 6.696 -7.946 1.00 31.01 ? 52 LEU B O 1 ATOM 4323 C CB . LEU B 1 52 ? 14.431 7.599 -5.796 1.00 31.08 ? 52 LEU B CB 1 ATOM 4324 C CG . LEU B 1 52 ? 14.987 7.454 -4.377 1.00 30.52 ? 52 LEU B CG 1 ATOM 4325 C CD1 . LEU B 1 52 ? 14.163 8.309 -3.442 1.00 30.29 ? 52 LEU B CD1 1 ATOM 4326 C CD2 . LEU B 1 52 ? 14.984 6.001 -3.909 1.00 30.14 ? 52 LEU B CD2 1 ATOM 4327 N N . ILE B 1 53 ? 14.530 6.444 -9.255 1.00 29.74 ? 53 ILE B N 1 ATOM 4328 C CA . ILE B 1 53 ? 13.749 6.217 -10.461 1.00 28.55 ? 53 ILE B CA 1 ATOM 4329 C C . ILE B 1 53 ? 13.511 4.709 -10.592 1.00 27.32 ? 53 ILE B C 1 ATOM 4330 O O . ILE B 1 53 ? 14.326 3.986 -11.180 1.00 27.09 ? 53 ILE B O 1 ATOM 4331 C CB . ILE B 1 53 ? 14.430 6.834 -11.715 1.00 28.97 ? 53 ILE B CB 1 ATOM 4332 C CG1 . ILE B 1 53 ? 14.377 8.367 -11.640 1.00 29.37 ? 53 ILE B CG1 1 ATOM 4333 C CG2 . ILE B 1 53 ? 13.773 6.344 -13.004 1.00 28.82 ? 53 ILE B CG2 1 ATOM 4334 C CD1 . ILE B 1 53 ? 15.442 9.066 -12.470 1.00 29.26 ? 53 ILE B CD1 1 ATOM 4335 N N . PHE B 1 54 ? 12.395 4.257 -10.007 1.00 25.39 ? 54 PHE B N 1 ATOM 4336 C CA . PHE B 1 54 ? 12.014 2.841 -9.967 1.00 23.50 ? 54 PHE B CA 1 ATOM 4337 C C . PHE B 1 54 ? 10.608 2.632 -10.530 1.00 22.78 ? 54 PHE B C 1 ATOM 4338 O O . PHE B 1 54 ? 9.626 2.979 -9.878 1.00 22.89 ? 54 PHE B O 1 ATOM 4339 C CB . PHE B 1 54 ? 12.096 2.313 -8.536 1.00 22.96 ? 54 PHE B CB 1 ATOM 4340 C CG . PHE B 1 54 ? 11.840 0.841 -8.414 1.00 21.35 ? 54 PHE B CG 1 ATOM 4341 C CD1 . PHE B 1 54 ? 12.608 -0.078 -9.128 1.00 19.08 ? 54 PHE B CD1 1 ATOM 4342 C CD2 . PHE B 1 54 ? 10.839 0.367 -7.564 1.00 19.18 ? 54 PHE B CD2 1 ATOM 4343 C CE1 . PHE B 1 54 ? 12.374 -1.452 -9.014 1.00 18.71 ? 54 PHE B CE1 1 ATOM 4344 C CE2 . PHE B 1 54 ? 10.595 -1.011 -7.439 1.00 18.30 ? 54 PHE B CE2 1 ATOM 4345 C CZ . PHE B 1 54 ? 11.366 -1.922 -8.159 1.00 18.07 ? 54 PHE B CZ 1 ATOM 4346 N N . PRO B 1 55 ? 10.506 2.056 -11.742 1.00 22.00 ? 55 PRO B N 1 ATOM 4347 C CA . PRO B 1 55 ? 9.232 2.050 -12.480 1.00 21.68 ? 55 PRO B CA 1 ATOM 4348 C C . PRO B 1 55 ? 7.981 1.544 -11.729 1.00 21.45 ? 55 PRO B C 1 ATOM 4349 O O . PRO B 1 55 ? 6.962 2.236 -11.762 1.00 21.56 ? 55 PRO B O 1 ATOM 4350 C CB . PRO B 1 55 ? 9.551 1.212 -13.723 1.00 21.63 ? 55 PRO B CB 1 ATOM 4351 C CG . PRO B 1 55 ? 11.011 1.461 -13.942 1.00 21.19 ? 55 PRO B CG 1 ATOM 4352 C CD . PRO B 1 55 ? 11.600 1.491 -12.556 1.00 21.63 ? 55 PRO B CD 1 ATOM 4353 N N . PRO B 1 56 ? 8.049 0.383 -11.029 1.00 21.39 ? 56 PRO B N 1 ATOM 4354 C CA . PRO B 1 56 ? 6.840 -0.052 -10.295 1.00 21.46 ? 56 PRO B CA 1 ATOM 4355 C C . PRO B 1 56 ? 6.317 0.954 -9.262 1.00 21.62 ? 56 PRO B C 1 ATOM 4356 O O . PRO B 1 56 ? 5.123 0.960 -8.960 1.00 21.45 ? 56 PRO B O 1 ATOM 4357 C CB . PRO B 1 56 ? 7.299 -1.333 -9.589 1.00 21.26 ? 56 PRO B CB 1 ATOM 4358 C CG . PRO B 1 56 ? 8.432 -1.824 -10.430 1.00 21.16 ? 56 PRO B CG 1 ATOM 4359 C CD . PRO B 1 56 ? 9.150 -0.583 -10.852 1.00 20.99 ? 56 PRO B CD 1 ATOM 4360 N N . SER B 1 57 ? 7.204 1.789 -8.731 1.00 22.05 ? 57 SER B N 1 ATOM 4361 C CA . SER B 1 57 ? 6.811 2.809 -7.764 1.00 22.72 ? 57 SER B CA 1 ATOM 4362 C C . SER B 1 57 ? 6.216 4.064 -8.412 1.00 22.82 ? 57 SER B C 1 ATOM 4363 O O . SER B 1 57 ? 5.588 4.866 -7.733 1.00 23.12 ? 57 SER B O 1 ATOM 4364 C CB . SER B 1 57 ? 7.993 3.177 -6.870 1.00 22.72 ? 57 SER B CB 1 ATOM 4365 O OG . SER B 1 57 ? 9.009 3.784 -7.640 1.00 23.93 ? 57 SER B OG 1 ATOM 4366 N N . MET B 1 58 ? 6.414 4.238 -9.713 1.00 23.21 ? 58 MET B N 1 ATOM 4367 C CA . MET B 1 58 ? 5.807 5.359 -10.428 1.00 23.78 ? 58 MET B CA 1 ATOM 4368 C C . MET B 1 58 ? 4.509 4.908 -11.067 1.00 23.66 ? 58 MET B C 1 ATOM 4369 O O . MET B 1 58 ? 4.258 3.715 -11.209 1.00 23.89 ? 58 MET B O 1 ATOM 4370 C CB . MET B 1 58 ? 6.719 5.878 -11.541 1.00 24.04 ? 58 MET B CB 1 ATOM 4371 C CG . MET B 1 58 ? 8.136 6.164 -11.144 1.00 25.90 ? 58 MET B CG 1 ATOM 4372 S SD . MET B 1 58 ? 9.098 6.610 -12.594 1.00 31.13 ? 58 MET B SD 1 ATOM 4373 C CE . MET B 1 58 ? 10.554 5.654 -12.206 1.00 30.85 ? 58 MET B CE 1 ATOM 4374 N N . HIS B 1 59 ? 3.695 5.867 -11.482 1.00 23.63 ? 59 HIS B N 1 ATOM 4375 C CA . HIS B 1 59 ? 2.501 5.556 -12.256 1.00 23.69 ? 59 HIS B CA 1 ATOM 4376 C C . HIS B 1 59 ? 2.897 4.963 -13.606 1.00 23.92 ? 59 HIS B C 1 ATOM 4377 O O . HIS B 1 59 ? 3.788 5.478 -14.283 1.00 23.98 ? 59 HIS B O 1 ATOM 4378 C CB . HIS B 1 59 ? 1.673 6.808 -12.468 1.00 23.15 ? 59 HIS B CB 1 ATOM 4379 C CG . HIS B 1 59 ? 0.273 6.528 -12.893 1.00 22.90 ? 59 HIS B CG 1 ATOM 4380 N ND1 . HIS B 1 59 ? -0.031 5.913 -14.090 1.00 22.06 ? 59 HIS B ND1 1 ATOM 4381 C CD2 . HIS B 1 59 ? -0.909 6.779 -12.285 1.00 22.14 ? 59 HIS B CD2 1 ATOM 4382 C CE1 . HIS B 1 59 ? -1.341 5.794 -14.196 1.00 21.52 ? 59 HIS B CE1 1 ATOM 4383 N NE2 . HIS B 1 59 ? -1.897 6.318 -13.119 1.00 21.98 ? 59 HIS B NE2 1 ATOM 4384 N N . PHE B 1 60 ? 2.232 3.881 -13.994 1.00 24.01 ? 60 PHE B N 1 ATOM 4385 C CA . PHE B 1 60 ? 2.578 3.165 -15.226 1.00 24.11 ? 60 PHE B CA 1 ATOM 4386 C C . PHE B 1 60 ? 2.631 4.054 -16.491 1.00 24.46 ? 60 PHE B C 1 ATOM 4387 O O . PHE B 1 60 ? 3.435 3.812 -17.402 1.00 24.70 ? 60 PHE B O 1 ATOM 4388 C CB . PHE B 1 60 ? 1.652 1.956 -15.431 1.00 23.73 ? 60 PHE B CB 1 ATOM 4389 C CG . PHE B 1 60 ? 1.911 1.208 -16.703 1.00 22.97 ? 60 PHE B CG 1 ATOM 4390 C CD1 . PHE B 1 60 ? 3.072 0.466 -16.860 1.00 21.79 ? 60 PHE B CD1 1 ATOM 4391 C CD2 . PHE B 1 60 ? 0.999 1.268 -17.759 1.00 22.46 ? 60 PHE B CD2 1 ATOM 4392 C CE1 . PHE B 1 60 ? 3.331 -0.217 -18.043 1.00 22.21 ? 60 PHE B CE1 1 ATOM 4393 C CE2 . PHE B 1 60 ? 1.249 0.593 -18.957 1.00 22.90 ? 60 PHE B CE2 1 ATOM 4394 C CZ . PHE B 1 60 ? 2.417 -0.153 -19.098 1.00 21.94 ? 60 PHE B CZ 1 ATOM 4395 N N . PHE B 1 61 ? 1.792 5.082 -16.541 1.00 24.70 ? 61 PHE B N 1 ATOM 4396 C CA . PHE B 1 61 ? 1.791 5.994 -17.679 1.00 25.08 ? 61 PHE B CA 1 ATOM 4397 C C . PHE B 1 61 ? 3.154 6.650 -17.849 1.00 25.63 ? 61 PHE B C 1 ATOM 4398 O O . PHE B 1 61 ? 3.657 6.762 -18.963 1.00 25.94 ? 61 PHE B O 1 ATOM 4399 C CB . PHE B 1 61 ? 0.712 7.073 -17.533 1.00 24.97 ? 61 PHE B CB 1 ATOM 4400 C CG . PHE B 1 61 ? -0.695 6.544 -17.522 1.00 23.81 ? 61 PHE B CG 1 ATOM 4401 C CD1 . PHE B 1 61 ? -0.987 5.268 -17.997 1.00 22.61 ? 61 PHE B CD1 1 ATOM 4402 C CD2 . PHE B 1 61 ? -1.739 7.351 -17.058 1.00 22.99 ? 61 PHE B CD2 1 ATOM 4403 C CE1 . PHE B 1 61 ? -2.286 4.795 -17.990 1.00 22.39 ? 61 PHE B CE1 1 ATOM 4404 C CE2 . PHE B 1 61 ? -3.043 6.892 -17.048 1.00 21.59 ? 61 PHE B CE2 1 ATOM 4405 C CZ . PHE B 1 61 ? -3.322 5.613 -17.516 1.00 22.04 ? 61 PHE B CZ 1 ATOM 4406 N N . GLN B 1 62 ? 3.751 7.064 -16.737 1.00 26.23 ? 62 GLN B N 1 ATOM 4407 C CA . GLN B 1 62 ? 5.056 7.712 -16.756 1.00 26.67 ? 62 GLN B CA 1 ATOM 4408 C C . GLN B 1 62 ? 6.205 6.708 -16.784 1.00 26.97 ? 62 GLN B C 1 ATOM 4409 O O . GLN B 1 62 ? 7.279 7.017 -17.292 1.00 27.49 ? 62 GLN B O 1 ATOM 4410 C CB . GLN B 1 62 ? 5.197 8.683 -15.576 1.00 26.53 ? 62 GLN B CB 1 ATOM 4411 C CG . GLN B 1 62 ? 4.486 10.028 -15.780 1.00 27.43 ? 62 GLN B CG 1 ATOM 4412 C CD . GLN B 1 62 ? 2.979 9.883 -15.961 1.00 28.90 ? 62 GLN B CD 1 ATOM 4413 O OE1 . GLN B 1 62 ? 2.435 10.175 -17.029 1.00 29.61 ? 62 GLN B OE1 1 ATOM 4414 N NE2 . GLN B 1 62 ? 2.303 9.408 -14.925 1.00 29.59 ? 62 GLN B NE2 1 ATOM 4415 N N . ALA B 1 63 ? 5.971 5.506 -16.267 1.00 27.33 ? 63 ALA B N 1 ATOM 4416 C CA . ALA B 1 63 ? 7.018 4.482 -16.139 1.00 27.93 ? 63 ALA B CA 1 ATOM 4417 C C . ALA B 1 63 ? 7.201 3.602 -17.378 1.00 28.32 ? 63 ALA B C 1 ATOM 4418 O O . ALA B 1 63 ? 8.224 2.928 -17.517 1.00 28.51 ? 63 ALA B O 1 ATOM 4419 C CB . ALA B 1 63 ? 6.740 3.597 -14.919 1.00 27.92 ? 63 ALA B CB 1 ATOM 4420 N N . LYS B 1 64 ? 6.207 3.592 -18.257 1.00 28.94 ? 64 LYS B N 1 ATOM 4421 C CA . LYS B 1 64 ? 6.181 2.676 -19.400 1.00 29.83 ? 64 LYS B CA 1 ATOM 4422 C C . LYS B 1 64 ? 7.425 2.757 -20.295 1.00 30.18 ? 64 LYS B C 1 ATOM 4423 O O . LYS B 1 64 ? 8.034 1.719 -20.619 1.00 30.24 ? 64 LYS B O 1 ATOM 4424 C CB . LYS B 1 64 ? 4.915 2.895 -20.231 1.00 29.82 ? 64 LYS B CB 1 ATOM 4425 C CG . LYS B 1 64 ? 4.819 1.993 -21.440 1.00 30.79 ? 64 LYS B CG 1 ATOM 4426 C CD . LYS B 1 64 ? 3.706 2.454 -22.360 1.00 32.41 ? 64 LYS B CD 1 ATOM 4427 C CE . LYS B 1 64 ? 3.742 1.699 -23.665 1.00 33.64 ? 64 LYS B CE 1 ATOM 4428 N NZ . LYS B 1 64 ? 2.676 2.178 -24.572 1.00 35.00 ? 64 LYS B NZ 1 ATOM 4429 N N . HIS B 1 65 ? 7.795 3.981 -20.687 1.00 30.35 ? 65 HIS B N 1 ATOM 4430 C CA . HIS B 1 65 ? 8.981 4.199 -21.526 1.00 30.85 ? 65 HIS B CA 1 ATOM 4431 C C . HIS B 1 65 ? 10.274 3.715 -20.848 1.00 30.75 ? 65 HIS B C 1 ATOM 4432 O O . HIS B 1 65 ? 11.199 3.264 -21.529 1.00 30.93 ? 65 HIS B O 1 ATOM 4433 C CB . HIS B 1 65 ? 9.092 5.658 -21.999 1.00 31.09 ? 65 HIS B CB 1 ATOM 4434 C CG . HIS B 1 65 ? 9.448 6.635 -20.918 1.00 33.01 ? 65 HIS B CG 1 ATOM 4435 N ND1 . HIS B 1 65 ? 10.725 7.127 -20.750 1.00 34.31 ? 65 HIS B ND1 1 ATOM 4436 C CD2 . HIS B 1 65 ? 8.691 7.227 -19.962 1.00 34.19 ? 65 HIS B CD2 1 ATOM 4437 C CE1 . HIS B 1 65 ? 10.742 7.973 -19.735 1.00 34.76 ? 65 HIS B CE1 1 ATOM 4438 N NE2 . HIS B 1 65 ? 9.520 8.046 -19.236 1.00 35.07 ? 65 HIS B NE2 1 ATOM 4439 N N . LEU B 1 66 ? 10.321 3.789 -19.515 1.00 30.42 ? 66 LEU B N 1 ATOM 4440 C CA . LEU B 1 66 ? 11.468 3.277 -18.751 1.00 30.18 ? 66 LEU B CA 1 ATOM 4441 C C . LEU B 1 66 ? 11.487 1.750 -18.712 1.00 30.14 ? 66 LEU B C 1 ATOM 4442 O O . LEU B 1 66 ? 12.552 1.139 -18.809 1.00 30.20 ? 66 LEU B O 1 ATOM 4443 C CB . LEU B 1 66 ? 11.512 3.861 -17.328 1.00 29.83 ? 66 LEU B CB 1 ATOM 4444 C CG . LEU B 1 66 ? 11.685 5.379 -17.199 1.00 29.68 ? 66 LEU B CG 1 ATOM 4445 C CD1 . LEU B 1 66 ? 11.356 5.836 -15.792 1.00 28.94 ? 66 LEU B CD1 1 ATOM 4446 C CD2 . LEU B 1 66 ? 13.084 5.850 -17.617 1.00 28.17 ? 66 LEU B CD2 1 ATOM 4447 N N . ILE B 1 67 ? 10.310 1.144 -18.578 1.00 30.16 ? 67 ILE B N 1 ATOM 4448 C CA . ILE B 1 67 ? 10.176 -0.317 -18.570 1.00 30.25 ? 67 ILE B CA 1 ATOM 4449 C C . ILE B 1 67 ? 10.635 -0.905 -19.918 1.00 30.72 ? 67 ILE B C 1 ATOM 4450 O O . ILE B 1 67 ? 11.254 -1.968 -19.974 1.00 30.47 ? 67 ILE B O 1 ATOM 4451 C CB . ILE B 1 67 ? 8.712 -0.745 -18.241 1.00 29.99 ? 67 ILE B CB 1 ATOM 4452 C CG1 . ILE B 1 67 ? 8.332 -0.295 -16.823 1.00 29.58 ? 67 ILE B CG1 1 ATOM 4453 C CG2 . ILE B 1 67 ? 8.522 -2.248 -18.415 1.00 29.33 ? 67 ILE B CG2 1 ATOM 4454 C CD1 . ILE B 1 67 ? 6.847 -0.474 -16.456 1.00 28.92 ? 67 ILE B CD1 1 ATOM 4455 N N . GLU B 1 68 ? 10.337 -0.179 -20.992 1.00 31.49 ? 68 GLU B N 1 ATOM 4456 C CA . GLU B 1 68 ? 10.708 -0.574 -22.342 1.00 32.27 ? 68 GLU B CA 1 ATOM 4457 C C . GLU B 1 68 ? 12.216 -0.549 -22.599 1.00 32.45 ? 68 GLU B C 1 ATOM 4458 O O . GLU B 1 68 ? 12.707 -1.253 -23.471 1.00 32.39 ? 68 GLU B O 1 ATOM 4459 C CB . GLU B 1 68 ? 9.941 0.268 -23.360 1.00 32.35 ? 68 GLU B CB 1 ATOM 4460 C CG . GLU B 1 68 ? 8.538 -0.261 -23.580 1.00 33.77 ? 68 GLU B CG 1 ATOM 4461 C CD . GLU B 1 68 ? 7.589 0.738 -24.219 1.00 36.67 ? 68 GLU B CD 1 ATOM 4462 O OE1 . GLU B 1 68 ? 7.954 1.924 -24.395 1.00 38.54 ? 68 GLU B OE1 1 ATOM 4463 O OE2 . GLU B 1 68 ? 6.452 0.329 -24.539 1.00 37.60 ? 68 GLU B OE2 1 ATOM 4464 N N . ARG B 1 69 ? 12.942 0.243 -21.816 1.00 33.21 ? 69 ARG B N 1 ATOM 4465 C CA . ARG B 1 69 ? 14.411 0.295 -21.887 1.00 33.81 ? 69 ARG B CA 1 ATOM 4466 C C . ARG B 1 69 ? 15.089 -0.741 -20.987 1.00 33.16 ? 69 ARG B C 1 ATOM 4467 O O . ARG B 1 69 ? 16.318 -0.790 -20.912 1.00 33.43 ? 69 ARG B O 1 ATOM 4468 C CB . ARG B 1 69 ? 14.914 1.695 -21.521 1.00 34.18 ? 69 ARG B CB 1 ATOM 4469 C CG . ARG B 1 69 ? 14.796 2.714 -22.650 1.00 37.54 ? 69 ARG B CG 1 ATOM 4470 C CD . ARG B 1 69 ? 14.595 4.140 -22.116 1.00 43.94 ? 69 ARG B CD 1 ATOM 4471 N NE . ARG B 1 69 ? 15.764 4.678 -21.413 1.00 48.80 ? 69 ARG B NE 1 ATOM 4472 C CZ . ARG B 1 69 ? 15.792 5.848 -20.769 1.00 51.26 ? 69 ARG B CZ 1 ATOM 4473 N NH1 . ARG B 1 69 ? 14.715 6.626 -20.720 1.00 52.34 ? 69 ARG B NH1 1 ATOM 4474 N NH2 . ARG B 1 69 ? 16.905 6.244 -20.165 1.00 52.30 ? 69 ARG B NH2 1 ATOM 4475 N N . SER B 1 70 ? 14.292 -1.569 -20.314 1.00 32.30 ? 70 SER B N 1 ATOM 4476 C CA . SER B 1 70 ? 14.818 -2.498 -19.316 1.00 31.46 ? 70 SER B CA 1 ATOM 4477 C C . SER B 1 70 ? 15.199 -3.849 -19.913 1.00 31.42 ? 70 SER B C 1 ATOM 4478 O O . SER B 1 70 ? 14.410 -4.480 -20.635 1.00 31.27 ? 70 SER B O 1 ATOM 4479 C CB . SER B 1 70 ? 13.819 -2.673 -18.166 1.00 31.18 ? 70 SER B CB 1 ATOM 4480 O OG . SER B 1 70 ? 14.105 -3.821 -17.381 1.00 29.97 ? 70 SER B OG 1 ATOM 4481 N N . GLN B 1 71 ? 16.416 -4.287 -19.599 1.00 31.17 ? 71 GLN B N 1 ATOM 4482 C CA . GLN B 1 71 ? 16.912 -5.588 -20.033 1.00 31.00 ? 71 GLN B CA 1 ATOM 4483 C C . GLN B 1 71 ? 16.091 -6.706 -19.410 1.00 30.47 ? 71 GLN B C 1 ATOM 4484 O O . GLN B 1 71 ? 15.954 -7.777 -20.005 1.00 30.71 ? 71 GLN B O 1 ATOM 4485 C CB . GLN B 1 71 ? 18.390 -5.767 -19.676 1.00 31.33 ? 71 GLN B CB 1 ATOM 4486 C CG . GLN B 1 71 ? 19.314 -4.678 -20.205 1.00 32.96 ? 71 GLN B CG 1 ATOM 4487 C CD . GLN B 1 71 ? 19.457 -4.679 -21.721 1.00 35.99 ? 71 GLN B CD 1 ATOM 4488 O OE1 . GLN B 1 71 ? 19.201 -5.680 -22.398 1.00 36.48 ? 71 GLN B OE1 1 ATOM 4489 N NE2 . GLN B 1 71 ? 19.887 -3.548 -22.261 1.00 37.13 ? 71 GLN B NE2 1 ATOM 4490 N N . VAL B 1 72 ? 15.558 -6.459 -18.212 1.00 29.64 ? 72 VAL B N 1 ATOM 4491 C CA . VAL B 1 72 ? 14.670 -7.415 -17.533 1.00 29.01 ? 72 VAL B CA 1 ATOM 4492 C C . VAL B 1 72 ? 13.341 -7.568 -18.300 1.00 28.90 ? 72 VAL B C 1 ATOM 4493 O O . VAL B 1 72 ? 12.895 -8.687 -18.577 1.00 28.46 ? 72 VAL B O 1 ATOM 4494 C CB . VAL B 1 72 ? 14.428 -7.024 -16.049 1.00 28.90 ? 72 VAL B CB 1 ATOM 4495 C CG1 . VAL B 1 72 ? 13.292 -7.837 -15.442 1.00 28.34 ? 72 VAL B CG1 1 ATOM 4496 C CG2 . VAL B 1 72 ? 15.710 -7.220 -15.227 1.00 28.99 ? 72 VAL B CG2 1 ATOM 4497 N N . PHE B 1 73 ? 12.726 -6.437 -18.646 1.00 28.63 ? 73 PHE B N 1 ATOM 4498 C CA . PHE B 1 73 ? 11.533 -6.427 -19.473 1.00 28.75 ? 73 PHE B CA 1 ATOM 4499 C C . PHE B 1 73 ? 11.772 -7.185 -20.779 1.00 29.14 ? 73 PHE B C 1 ATOM 4500 O O . PHE B 1 73 ? 10.975 -8.036 -21.176 1.00 28.96 ? 73 PHE B O 1 ATOM 4501 C CB . PHE B 1 73 ? 11.108 -4.993 -19.778 1.00 28.33 ? 73 PHE B CB 1 ATOM 4502 C CG . PHE B 1 73 ? 9.906 -4.898 -20.667 1.00 27.75 ? 73 PHE B CG 1 ATOM 4503 C CD1 . PHE B 1 73 ? 8.643 -5.281 -20.199 1.00 26.28 ? 73 PHE B CD1 1 ATOM 4504 C CD2 . PHE B 1 73 ? 10.028 -4.433 -21.979 1.00 27.01 ? 73 PHE B CD2 1 ATOM 4505 C CE1 . PHE B 1 73 ? 7.511 -5.188 -21.021 1.00 26.43 ? 73 PHE B CE1 1 ATOM 4506 C CE2 . PHE B 1 73 ? 8.898 -4.340 -22.819 1.00 27.16 ? 73 PHE B CE2 1 ATOM 4507 C CZ . PHE B 1 73 ? 7.635 -4.712 -22.333 1.00 26.22 ? 73 PHE B CZ 1 ATOM 4508 N N . ASN B 1 74 ? 12.883 -6.869 -21.433 1.00 29.75 ? 74 ASN B N 1 ATOM 4509 C CA . ASN B 1 74 ? 13.271 -7.536 -22.659 1.00 30.39 ? 74 ASN B CA 1 ATOM 4510 C C . ASN B 1 74 ? 13.244 -9.065 -22.518 1.00 29.91 ? 74 ASN B C 1 ATOM 4511 O O . ASN B 1 74 ? 12.642 -9.763 -23.335 1.00 29.81 ? 74 ASN B O 1 ATOM 4512 C CB . ASN B 1 74 ? 14.655 -7.059 -23.090 1.00 31.06 ? 74 ASN B CB 1 ATOM 4513 C CG . ASN B 1 74 ? 15.020 -7.545 -24.467 1.00 33.95 ? 74 ASN B CG 1 ATOM 4514 O OD1 . ASN B 1 74 ? 14.481 -7.060 -25.464 1.00 37.39 ? 74 ASN B OD1 1 ATOM 4515 N ND2 . ASN B 1 74 ? 15.933 -8.521 -24.538 1.00 36.51 ? 74 ASN B ND2 1 ATOM 4516 N N . ILE B 1 75 ? 13.883 -9.571 -21.466 1.00 29.33 ? 75 ILE B N 1 ATOM 4517 C CA . ILE B 1 75 ? 13.873 -10.994 -21.163 1.00 29.01 ? 75 ILE B CA 1 ATOM 4518 C C . ILE B 1 75 ? 12.454 -11.511 -20.913 1.00 29.24 ? 75 ILE B C 1 ATOM 4519 O O . ILE B 1 75 ? 12.104 -12.595 -21.365 1.00 29.50 ? 75 ILE B O 1 ATOM 4520 C CB . ILE B 1 75 ? 14.839 -11.323 -19.991 1.00 29.04 ? 75 ILE B CB 1 ATOM 4521 C CG1 . ILE B 1 75 ? 16.286 -11.295 -20.499 1.00 28.92 ? 75 ILE B CG1 1 ATOM 4522 C CG2 . ILE B 1 75 ? 14.520 -12.681 -19.342 1.00 27.82 ? 75 ILE B CG2 1 ATOM 4523 C CD1 . ILE B 1 75 ? 17.328 -11.109 -19.404 1.00 29.66 ? 75 ILE B CD1 1 ATOM 4524 N N . LEU B 1 76 ? 11.630 -10.728 -20.224 1.00 29.50 ? 76 LEU B N 1 ATOM 4525 C CA . LEU B 1 76 ? 10.249 -11.138 -19.946 1.00 29.72 ? 76 LEU B CA 1 ATOM 4526 C C . LEU B 1 76 ? 9.364 -11.156 -21.196 1.00 30.38 ? 76 LEU B C 1 ATOM 4527 O O . LEU B 1 76 ? 8.423 -11.945 -21.272 1.00 30.20 ? 76 LEU B O 1 ATOM 4528 C CB . LEU B 1 76 ? 9.618 -10.269 -18.844 1.00 29.31 ? 76 LEU B CB 1 ATOM 4529 C CG . LEU B 1 76 ? 10.284 -10.294 -17.463 1.00 27.86 ? 76 LEU B CG 1 ATOM 4530 C CD1 . LEU B 1 76 ? 9.619 -9.302 -16.558 1.00 25.35 ? 76 LEU B CD1 1 ATOM 4531 C CD2 . LEU B 1 76 ? 10.250 -11.662 -16.837 1.00 26.88 ? 76 LEU B CD2 1 ATOM 4532 N N . ARG B 1 77 ? 9.664 -10.289 -22.163 1.00 31.41 ? 77 ARG B N 1 ATOM 4533 C CA . ARG B 1 77 ? 8.996 -10.318 -23.469 1.00 32.74 ? 77 ARG B CA 1 ATOM 4534 C C . ARG B 1 77 ? 9.200 -11.678 -24.128 1.00 32.99 ? 77 ARG B C 1 ATOM 4535 O O . ARG B 1 77 ? 8.269 -12.239 -24.700 1.00 33.19 ? 77 ARG B O 1 ATOM 4536 C CB . ARG B 1 77 ? 9.528 -9.214 -24.397 1.00 33.10 ? 77 ARG B CB 1 ATOM 4537 C CG . ARG B 1 77 ? 8.992 -7.821 -24.152 1.00 35.00 ? 77 ARG B CG 1 ATOM 4538 C CD . ARG B 1 77 ? 7.481 -7.768 -24.321 1.00 39.77 ? 77 ARG B CD 1 ATOM 4539 N NE . ARG B 1 77 ? 6.993 -7.331 -25.638 1.00 43.33 ? 77 ARG B NE 1 ATOM 4540 C CZ . ARG B 1 77 ? 7.035 -8.057 -26.755 1.00 45.00 ? 77 ARG B CZ 1 ATOM 4541 N NH1 . ARG B 1 77 ? 7.591 -9.261 -26.754 1.00 47.04 ? 77 ARG B NH1 1 ATOM 4542 N NH2 . ARG B 1 77 ? 6.536 -7.575 -27.887 1.00 45.44 ? 77 ARG B NH2 1 ATOM 4543 N N . MET B 1 78 ? 10.424 -12.197 -24.022 1.00 33.56 ? 78 MET B N 1 ATOM 4544 C CA . MET B 1 78 ? 10.821 -13.477 -24.621 1.00 34.20 ? 78 MET B CA 1 ATOM 4545 C C . MET B 1 78 ? 10.186 -14.692 -23.950 1.00 33.88 ? 78 MET B C 1 ATOM 4546 O O . MET B 1 78 ? 10.057 -15.750 -24.570 1.00 34.19 ? 78 MET B O 1 ATOM 4547 C CB . MET B 1 78 ? 12.345 -13.643 -24.564 1.00 34.61 ? 78 MET B CB 1 ATOM 4548 C CG . MET B 1 78 ? 13.136 -12.769 -25.536 1.00 36.52 ? 78 MET B CG 1 ATOM 4549 S SD . MET B 1 78 ? 14.845 -12.511 -24.973 1.00 42.81 ? 78 MET B SD 1 ATOM 4550 C CE . MET B 1 78 ? 15.511 -14.178 -24.945 1.00 39.97 ? 78 MET B CE 1 ATOM 4551 N N . MET B 1 79 ? 9.810 -14.541 -22.685 1.00 33.39 ? 79 MET B N 1 ATOM 4552 C CA . MET B 1 79 ? 9.381 -15.670 -21.867 1.00 33.16 ? 79 MET B CA 1 ATOM 4553 C C . MET B 1 79 ? 8.034 -16.232 -22.298 1.00 32.43 ? 79 MET B C 1 ATOM 4554 O O . MET B 1 79 ? 7.085 -15.472 -22.498 1.00 32.10 ? 79 MET B O 1 ATOM 4555 C CB . MET B 1 79 ? 9.307 -15.258 -20.400 1.00 33.61 ? 79 MET B CB 1 ATOM 4556 C CG . MET B 1 79 ? 9.318 -16.423 -19.438 1.00 35.04 ? 79 MET B CG 1 ATOM 4557 S SD . MET B 1 79 ? 8.966 -15.846 -17.780 1.00 37.32 ? 79 MET B SD 1 ATOM 4558 C CE . MET B 1 79 ? 7.252 -16.321 -17.592 1.00 37.42 ? 79 MET B CE 1 ATOM 4559 N N . PRO B 1 80 ? 7.955 -17.569 -22.457 1.00 31.86 ? 80 PRO B N 1 ATOM 4560 C CA . PRO B 1 80 ? 6.668 -18.231 -22.656 1.00 31.27 ? 80 PRO B CA 1 ATOM 4561 C C . PRO B 1 80 ? 5.872 -18.168 -21.349 1.00 30.59 ? 80 PRO B C 1 ATOM 4562 O O . PRO B 1 80 ? 6.190 -18.865 -20.383 1.00 30.50 ? 80 PRO B O 1 ATOM 4563 C CB . PRO B 1 80 ? 7.064 -19.667 -23.014 1.00 31.31 ? 80 PRO B CB 1 ATOM 4564 C CG . PRO B 1 80 ? 8.416 -19.851 -22.401 1.00 31.38 ? 80 PRO B CG 1 ATOM 4565 C CD . PRO B 1 80 ? 9.081 -18.520 -22.534 1.00 31.88 ? 80 PRO B CD 1 ATOM 4566 N N . LYS B 1 81 ? 4.860 -17.310 -21.316 1.00 29.76 ? 81 LYS B N 1 ATOM 4567 C CA . LYS B 1 81 ? 4.194 -16.982 -20.058 1.00 28.91 ? 81 LYS B CA 1 ATOM 4568 C C . LYS B 1 81 ? 2.998 -17.888 -19.734 1.00 28.80 ? 81 LYS B C 1 ATOM 4569 O O . LYS B 1 81 ? 2.452 -17.839 -18.629 1.00 28.82 ? 81 LYS B O 1 ATOM 4570 C CB . LYS B 1 81 ? 3.832 -15.496 -20.028 1.00 28.43 ? 81 LYS B CB 1 ATOM 4571 C CG . LYS B 1 81 ? 5.065 -14.602 -19.873 1.00 27.13 ? 81 LYS B CG 1 ATOM 4572 C CD . LYS B 1 81 ? 4.792 -13.140 -20.170 1.00 24.96 ? 81 LYS B CD 1 ATOM 4573 C CE . LYS B 1 81 ? 4.622 -12.883 -21.654 1.00 22.98 ? 81 LYS B CE 1 ATOM 4574 N NZ . LYS B 1 81 ? 5.916 -12.636 -22.329 1.00 21.68 ? 81 LYS B NZ 1 ATOM 4575 N N . GLY B 1 82 ? 2.630 -18.742 -20.689 1.00 28.48 ? 82 GLY B N 1 ATOM 4576 C CA . GLY B 1 82 ? 1.533 -19.687 -20.510 1.00 28.06 ? 82 GLY B CA 1 ATOM 4577 C C . GLY B 1 82 ? 0.212 -19.124 -21.008 1.00 27.63 ? 82 GLY B C 1 ATOM 4578 O O . GLY B 1 82 ? 0.023 -18.943 -22.215 1.00 27.73 ? 82 GLY B O 1 ATOM 4579 N N . ALA B 1 83 ? -0.697 -18.847 -20.072 1.00 27.03 ? 83 ALA B N 1 ATOM 4580 C CA . ALA B 1 83 ? -2.044 -18.373 -20.403 1.00 26.38 ? 83 ALA B CA 1 ATOM 4581 C C . ALA B 1 83 ? -2.395 -17.016 -19.781 1.00 25.86 ? 83 ALA B C 1 ATOM 4582 O O . ALA B 1 83 ? -1.916 -16.663 -18.700 1.00 25.73 ? 83 ALA B O 1 ATOM 4583 C CB . ALA B 1 83 ? -3.069 -19.410 -20.001 1.00 26.41 ? 83 ALA B CB 1 ATOM 4584 N N . ALA B 1 84 ? -3.216 -16.256 -20.493 1.00 25.08 ? 84 ALA B N 1 ATOM 4585 C CA . ALA B 1 84 ? -3.795 -15.044 -19.962 1.00 24.43 ? 84 ALA B CA 1 ATOM 4586 C C . ALA B 1 84 ? -5.200 -15.410 -19.504 1.00 24.28 ? 84 ALA B C 1 ATOM 4587 O O . ALA B 1 84 ? -6.070 -15.703 -20.317 1.00 24.44 ? 84 ALA B O 1 ATOM 4588 C CB . ALA B 1 84 ? -3.822 -13.965 -21.016 1.00 23.90 ? 84 ALA B CB 1 ATOM 4589 N N . LEU B 1 85 ? -5.408 -15.408 -18.194 1.00 24.24 ? 85 LEU B N 1 ATOM 4590 C CA . LEU B 1 85 ? -6.667 -15.863 -17.602 1.00 24.27 ? 85 LEU B CA 1 ATOM 4591 C C . LEU B 1 85 ? -7.677 -14.779 -17.154 1.00 24.56 ? 85 LEU B C 1 ATOM 4592 O O . LEU B 1 85 ? -8.847 -15.089 -16.911 1.00 24.85 ? 85 LEU B O 1 ATOM 4593 C CB . LEU B 1 85 ? -6.361 -16.818 -16.447 1.00 23.87 ? 85 LEU B CB 1 ATOM 4594 C CG . LEU B 1 85 ? -6.456 -18.335 -16.681 1.00 23.74 ? 85 LEU B CG 1 ATOM 4595 C CD1 . LEU B 1 85 ? -6.177 -18.791 -18.116 1.00 22.22 ? 85 LEU B CD1 1 ATOM 4596 C CD2 . LEU B 1 85 ? -5.583 -19.089 -15.675 1.00 22.83 ? 85 LEU B CD2 1 ATOM 4597 N N . HIS B 1 86 ? -7.236 -13.529 -17.029 1.00 24.54 ? 86 HIS B N 1 ATOM 4598 C CA . HIS B 1 86 ? -8.131 -12.442 -16.654 1.00 24.54 ? 86 HIS B CA 1 ATOM 4599 C C . HIS B 1 86 ? -8.063 -11.341 -17.703 1.00 24.39 ? 86 HIS B C 1 ATOM 4600 O O . HIS B 1 86 ? -7.147 -10.518 -17.689 1.00 23.94 ? 86 HIS B O 1 ATOM 4601 C CB . HIS B 1 86 ? -7.792 -11.899 -15.257 1.00 24.50 ? 86 HIS B CB 1 ATOM 4602 C CG . HIS B 1 86 ? -8.849 -11.004 -14.682 1.00 25.54 ? 86 HIS B CG 1 ATOM 4603 N ND1 . HIS B 1 86 ? -9.656 -11.384 -13.630 1.00 26.11 ? 86 HIS B ND1 1 ATOM 4604 C CD2 . HIS B 1 86 ? -9.243 -9.754 -15.024 1.00 26.63 ? 86 HIS B CD2 1 ATOM 4605 C CE1 . HIS B 1 86 ? -10.498 -10.406 -13.345 1.00 26.58 ? 86 HIS B CE1 1 ATOM 4606 N NE2 . HIS B 1 86 ? -10.269 -9.405 -14.176 1.00 27.08 ? 86 HIS B NE2 1 ATOM 4607 N N . LEU B 1 87 ? -9.037 -11.341 -18.613 1.00 24.65 ? 87 LEU B N 1 ATOM 4608 C CA . LEU B 1 87 ? -9.079 -10.378 -19.719 1.00 25.29 ? 87 LEU B CA 1 ATOM 4609 C C . LEU B 1 87 ? -10.510 -10.027 -20.044 1.00 25.99 ? 87 LEU B C 1 ATOM 4610 O O . LEU B 1 87 ? -11.415 -10.828 -19.815 1.00 26.18 ? 87 LEU B O 1 ATOM 4611 C CB . LEU B 1 87 ? -8.419 -10.951 -20.982 1.00 24.93 ? 87 LEU B CB 1 ATOM 4612 C CG . LEU B 1 87 ? -6.932 -11.306 -20.992 1.00 24.60 ? 87 LEU B CG 1 ATOM 4613 C CD1 . LEU B 1 87 ? -6.611 -12.015 -22.291 1.00 26.81 ? 87 LEU B CD1 1 ATOM 4614 C CD2 . LEU B 1 87 ? -6.037 -10.081 -20.815 1.00 22.99 ? 87 LEU B CD2 1 ATOM 4615 N N . HIS B 1 88 ? -10.709 -8.839 -20.604 1.00 27.12 ? 88 HIS B N 1 ATOM 4616 C CA . HIS B 1 88 ? -12.038 -8.402 -21.010 1.00 28.31 ? 88 HIS B CA 1 ATOM 4617 C C . HIS B 1 88 ? -12.166 -8.267 -22.516 1.00 28.78 ? 88 HIS B C 1 ATOM 4618 O O . HIS B 1 88 ? -11.215 -7.878 -23.199 1.00 29.13 ? 88 HIS B O 1 ATOM 4619 C CB . HIS B 1 88 ? -12.424 -7.116 -20.282 1.00 28.49 ? 88 HIS B CB 1 ATOM 4620 C CG . HIS B 1 88 ? -12.574 -7.308 -18.806 1.00 29.58 ? 88 HIS B CG 1 ATOM 4621 N ND1 . HIS B 1 88 ? -13.753 -7.727 -18.223 1.00 30.57 ? 88 HIS B ND1 1 ATOM 4622 C CD2 . HIS B 1 88 ? -11.679 -7.189 -17.799 1.00 30.25 ? 88 HIS B CD2 1 ATOM 4623 C CE1 . HIS B 1 88 ? -13.584 -7.830 -16.916 1.00 30.12 ? 88 HIS B CE1 1 ATOM 4624 N NE2 . HIS B 1 88 ? -12.336 -7.508 -16.633 1.00 30.70 ? 88 HIS B NE2 1 ATOM 4625 N N . ASP B 1 89 ? -13.354 -8.599 -23.014 1.00 29.34 ? 89 ASP B N 1 ATOM 4626 C CA . ASP B 1 89 ? -13.651 -8.639 -24.449 1.00 29.89 ? 89 ASP B CA 1 ATOM 4627 C C . ASP B 1 89 ? -13.065 -7.481 -25.264 1.00 30.08 ? 89 ASP B C 1 ATOM 4628 O O . ASP B 1 89 ? -12.440 -7.712 -26.302 1.00 30.33 ? 89 ASP B O 1 ATOM 4629 C CB . ASP B 1 89 ? -15.167 -8.775 -24.696 1.00 29.70 ? 89 ASP B CB 1 ATOM 4630 C CG . ASP B 1 89 ? -15.997 -7.818 -23.845 1.00 30.89 ? 89 ASP B CG 1 ATOM 4631 O OD1 . ASP B 1 89 ? -15.414 -6.932 -23.174 1.00 31.53 ? 89 ASP B OD1 1 ATOM 4632 O OD2 . ASP B 1 89 ? -17.243 -7.957 -23.847 1.00 31.34 ? 89 ASP B OD2 1 ATOM 4633 N N . ILE B 1 90 ? -13.244 -6.247 -24.795 1.00 30.04 ? 90 ILE B N 1 ATOM 4634 C CA . ILE B 1 90 ? -12.850 -5.086 -25.605 1.00 30.21 ? 90 ILE B CA 1 ATOM 4635 C C . ILE B 1 90 ? -11.709 -4.239 -25.036 1.00 30.19 ? 90 ILE B C 1 ATOM 4636 O O . ILE B 1 90 ? -11.599 -3.050 -25.353 1.00 30.59 ? 90 ILE B O 1 ATOM 4637 C CB . ILE B 1 90 ? -14.067 -4.187 -26.009 1.00 30.14 ? 90 ILE B CB 1 ATOM 4638 C CG1 . ILE B 1 90 ? -14.744 -3.571 -24.787 1.00 29.85 ? 90 ILE B CG1 1 ATOM 4639 C CG2 . ILE B 1 90 ? -15.064 -4.975 -26.858 1.00 30.35 ? 90 ILE B CG2 1 ATOM 4640 C CD1 . ILE B 1 90 ? -15.750 -2.492 -25.140 1.00 31.08 ? 90 ILE B CD1 1 ATOM 4641 N N . GLY B 1 91 ? -10.846 -4.848 -24.229 1.00 29.96 ? 91 GLY B N 1 ATOM 4642 C CA . GLY B 1 91 ? -9.691 -4.134 -23.700 1.00 29.54 ? 91 GLY B CA 1 ATOM 4643 C C . GLY B 1 91 ? -8.349 -4.751 -24.045 1.00 29.62 ? 91 GLY B C 1 ATOM 4644 O O . GLY B 1 91 ? -7.344 -4.441 -23.408 1.00 29.61 ? 91 GLY B O 1 ATOM 4645 N N . ILE B 1 92 ? -8.318 -5.605 -25.065 1.00 29.61 ? 92 ILE B N 1 ATOM 4646 C CA . ILE B 1 92 ? -7.144 -6.466 -25.308 1.00 29.91 ? 92 ILE B CA 1 ATOM 4647 C C . ILE B 1 92 ? -6.355 -6.220 -26.614 1.00 30.33 ? 92 ILE B C 1 ATOM 4648 O O . ILE B 1 92 ? -5.430 -6.970 -26.937 1.00 30.29 ? 92 ILE B O 1 ATOM 4649 C CB . ILE B 1 92 ? -7.522 -7.969 -25.184 1.00 29.61 ? 92 ILE B CB 1 ATOM 4650 C CG1 . ILE B 1 92 ? -8.737 -8.290 -26.065 1.00 29.06 ? 92 ILE B CG1 1 ATOM 4651 C CG2 . ILE B 1 92 ? -7.781 -8.322 -23.717 1.00 29.47 ? 92 ILE B CG2 1 ATOM 4652 C CD1 . ILE B 1 92 ? -9.324 -9.672 -25.858 1.00 27.60 ? 92 ILE B CD1 1 ATOM 4653 N N . VAL B 1 93 ? -6.719 -5.177 -27.354 1.00 30.76 ? 93 VAL B N 1 ATOM 4654 C CA . VAL B 1 93 ? -6.070 -4.864 -28.624 1.00 31.28 ? 93 VAL B CA 1 ATOM 4655 C C . VAL B 1 93 ? -5.620 -3.409 -28.619 1.00 32.04 ? 93 VAL B C 1 ATOM 4656 O O . VAL B 1 93 ? -6.421 -2.512 -28.336 1.00 32.24 ? 93 VAL B O 1 ATOM 4657 C CB . VAL B 1 93 ? -7.027 -5.102 -29.821 1.00 31.34 ? 93 VAL B CB 1 ATOM 4658 C CG1 . VAL B 1 93 ? -6.399 -4.624 -31.147 1.00 30.80 ? 93 VAL B CG1 1 ATOM 4659 C CG2 . VAL B 1 93 ? -7.421 -6.563 -29.917 1.00 30.48 ? 93 VAL B CG2 1 ATOM 4660 N N . THR B 1 94 ? -4.345 -3.183 -28.934 1.00 32.93 ? 94 THR B N 1 ATOM 4661 C CA . THR B 1 94 ? -3.772 -1.835 -28.975 1.00 34.11 ? 94 THR B CA 1 ATOM 4662 C C . THR B 1 94 ? -4.672 -0.894 -29.769 1.00 35.01 ? 94 THR B C 1 ATOM 4663 O O . THR B 1 94 ? -5.063 -1.209 -30.896 1.00 35.29 ? 94 THR B O 1 ATOM 4664 C CB . THR B 1 94 ? -2.359 -1.849 -29.578 1.00 33.93 ? 94 THR B CB 1 ATOM 4665 O OG1 . THR B 1 94 ? -1.583 -2.853 -28.921 1.00 34.29 ? 94 THR B OG1 1 ATOM 4666 C CG2 . THR B 1 94 ? -1.672 -0.501 -29.399 1.00 33.98 ? 94 THR B CG2 1 ATOM 4667 N N . MET B 1 95 ? -5.000 0.250 -29.167 1.00 36.19 ? 95 MET B N 1 ATOM 4668 C CA . MET B 1 95 ? -5.951 1.212 -29.741 1.00 37.28 ? 95 MET B CA 1 ATOM 4669 C C . MET B 1 95 ? -5.461 1.855 -31.037 1.00 38.14 ? 95 MET B C 1 ATOM 4670 O O . MET B 1 95 ? -6.268 2.305 -31.851 1.00 38.22 ? 95 MET B O 1 ATOM 4671 C CB . MET B 1 95 ? -6.314 2.289 -28.716 1.00 37.20 ? 95 MET B CB 1 ATOM 4672 C CG . MET B 1 95 ? -7.002 1.756 -27.475 1.00 36.95 ? 95 MET B CG 1 ATOM 4673 S SD . MET B 1 95 ? -8.603 1.003 -27.817 1.00 37.67 ? 95 MET B SD 1 ATOM 4674 C CE . MET B 1 95 ? -9.141 0.607 -26.159 1.00 35.66 ? 95 MET B CE 1 ATOM 4675 N N . ASP B 1 96 ? -4.139 1.893 -31.207 1.00 39.43 ? 96 ASP B N 1 ATOM 4676 C CA . ASP B 1 96 ? -3.494 2.329 -32.441 1.00 40.75 ? 96 ASP B CA 1 ATOM 4677 C C . ASP B 1 96 ? -4.227 1.773 -33.673 1.00 40.79 ? 96 ASP B C 1 ATOM 4678 O O . ASP B 1 96 ? -4.621 2.528 -34.576 1.00 40.65 ? 96 ASP B O 1 ATOM 4679 C CB . ASP B 1 96 ? -2.042 1.851 -32.437 1.00 41.49 ? 96 ASP B CB 1 ATOM 4680 C CG . ASP B 1 96 ? -1.104 2.834 -33.100 1.00 44.46 ? 96 ASP B CG 1 ATOM 4681 O OD1 . ASP B 1 96 ? -0.703 2.584 -34.259 1.00 48.72 ? 96 ASP B OD1 1 ATOM 4682 O OD2 . ASP B 1 96 ? -0.770 3.864 -32.467 1.00 48.16 ? 96 ASP B OD2 1 ATOM 4683 N N . TRP B 1 97 ? -4.422 0.453 -33.678 1.00 40.74 ? 97 TRP B N 1 ATOM 4684 C CA . TRP B 1 97 ? -5.112 -0.254 -34.754 1.00 40.61 ? 97 TRP B CA 1 ATOM 4685 C C . TRP B 1 97 ? -6.594 0.128 -34.884 1.00 40.58 ? 97 TRP B C 1 ATOM 4686 O O . TRP B 1 97 ? -7.136 0.107 -35.986 1.00 40.64 ? 97 TRP B O 1 ATOM 4687 C CB . TRP B 1 97 ? -4.950 -1.763 -34.572 1.00 40.63 ? 97 TRP B CB 1 ATOM 4688 C CG . TRP B 1 97 ? -5.706 -2.614 -35.559 1.00 40.76 ? 97 TRP B CG 1 ATOM 4689 C CD1 . TRP B 1 97 ? -5.277 -3.013 -36.790 1.00 40.98 ? 97 TRP B CD1 1 ATOM 4690 C CD2 . TRP B 1 97 ? -7.012 -3.184 -35.387 1.00 40.37 ? 97 TRP B CD2 1 ATOM 4691 N NE1 . TRP B 1 97 ? -6.234 -3.788 -37.399 1.00 40.65 ? 97 TRP B NE1 1 ATOM 4692 C CE2 . TRP B 1 97 ? -7.308 -3.911 -36.559 1.00 40.46 ? 97 TRP B CE2 1 ATOM 4693 C CE3 . TRP B 1 97 ? -7.961 -3.148 -34.356 1.00 40.36 ? 97 TRP B CE3 1 ATOM 4694 C CZ2 . TRP B 1 97 ? -8.513 -4.600 -36.731 1.00 40.46 ? 97 TRP B CZ2 1 ATOM 4695 C CZ3 . TRP B 1 97 ? -9.164 -3.830 -34.525 1.00 40.00 ? 97 TRP B CZ3 1 ATOM 4696 C CH2 . TRP B 1 97 ? -9.427 -4.547 -35.704 1.00 40.32 ? 97 TRP B CH2 1 ATOM 4697 N N . LEU B 1 98 ? -7.247 0.467 -33.774 1.00 40.56 ? 98 LEU B N 1 ATOM 4698 C CA . LEU B 1 98 ? -8.638 0.925 -33.835 1.00 40.65 ? 98 LEU B CA 1 ATOM 4699 C C . LEU B 1 98 ? -8.767 2.241 -34.595 1.00 41.30 ? 98 LEU B C 1 ATOM 4700 O O . LEU B 1 98 ? -9.677 2.402 -35.408 1.00 41.12 ? 98 LEU B O 1 ATOM 4701 C CB . LEU B 1 98 ? -9.263 1.067 -32.443 1.00 40.36 ? 98 LEU B CB 1 ATOM 4702 C CG . LEU B 1 98 ? -10.114 -0.048 -31.827 1.00 39.29 ? 98 LEU B CG 1 ATOM 4703 C CD1 . LEU B 1 98 ? -10.981 0.554 -30.733 1.00 37.70 ? 98 LEU B CD1 1 ATOM 4704 C CD2 . LEU B 1 98 ? -10.991 -0.770 -32.850 1.00 38.05 ? 98 LEU B CD2 1 ATOM 4705 N N . VAL B 1 99 ? -7.852 3.173 -34.330 1.00 42.29 ? 99 VAL B N 1 ATOM 4706 C CA . VAL B 1 99 ? -7.874 4.487 -34.975 1.00 43.14 ? 99 VAL B CA 1 ATOM 4707 C C . VAL B 1 99 ? -7.336 4.423 -36.407 1.00 44.02 ? 99 VAL B C 1 ATOM 4708 O O . VAL B 1 99 ? -8.051 4.768 -37.351 1.00 44.03 ? 99 VAL B O 1 ATOM 4709 C CB . VAL B 1 99 ? -7.109 5.556 -34.153 1.00 43.11 ? 99 VAL B CB 1 ATOM 4710 C CG1 . VAL B 1 99 ? -7.125 6.905 -34.869 1.00 42.75 ? 99 VAL B CG1 1 ATOM 4711 C CG2 . VAL B 1 99 ? -7.709 5.690 -32.771 1.00 42.58 ? 99 VAL B CG2 1 ATOM 4712 N N . ARG B 1 100 ? -6.090 3.968 -36.555 1.00 45.13 ? 100 ARG B N 1 ATOM 4713 C CA . ARG B 1 100 ? -5.394 3.965 -37.850 1.00 46.39 ? 100 ARG B CA 1 ATOM 4714 C C . ARG B 1 100 ? -6.021 3.038 -38.893 1.00 46.23 ? 100 ARG B C 1 ATOM 4715 O O . ARG B 1 100 ? -6.045 3.360 -40.084 1.00 46.37 ? 100 ARG B O 1 ATOM 4716 C CB . ARG B 1 100 ? -3.905 3.642 -37.670 1.00 46.97 ? 100 ARG B CB 1 ATOM 4717 C CG . ARG B 1 100 ? -3.081 4.815 -37.122 1.00 50.69 ? 100 ARG B CG 1 ATOM 4718 C CD . ARG B 1 100 ? -2.301 5.589 -38.205 1.00 57.31 ? 100 ARG B CD 1 ATOM 4719 N NE . ARG B 1 100 ? -3.068 5.836 -39.433 1.00 61.84 ? 100 ARG B NE 1 ATOM 4720 C CZ . ARG B 1 100 ? -2.705 5.433 -40.655 1.00 64.11 ? 100 ARG B CZ 1 ATOM 4721 N NH1 . ARG B 1 100 ? -1.566 4.769 -40.841 1.00 64.82 ? 100 ARG B NH1 1 ATOM 4722 N NH2 . ARG B 1 100 ? -3.480 5.704 -41.702 1.00 64.85 ? 100 ARG B NH2 1 ATOM 4723 N N . ASN B 1 101 ? -6.538 1.898 -38.442 1.00 45.95 ? 101 ASN B N 1 ATOM 4724 C CA . ASN B 1 101 ? -7.130 0.917 -39.342 1.00 45.57 ? 101 ASN B CA 1 ATOM 4725 C C . ASN B 1 101 ? -8.661 0.994 -39.389 1.00 44.96 ? 101 ASN B C 1 ATOM 4726 O O . ASN B 1 101 ? -9.240 1.224 -40.449 1.00 45.18 ? 101 ASN B O 1 ATOM 4727 C CB . ASN B 1 101 ? -6.644 -0.487 -38.975 1.00 45.91 ? 101 ASN B CB 1 ATOM 4728 C CG . ASN B 1 101 ? -7.106 -1.559 -39.956 1.00 47.38 ? 101 ASN B CG 1 ATOM 4729 O OD1 . ASN B 1 101 ? -8.312 -1.800 -40.131 1.00 46.85 ? 101 ASN B OD1 1 ATOM 4730 N ND2 . ASN B 1 101 ? -6.135 -2.223 -40.589 1.00 49.44 ? 101 ASN B ND2 1 ATOM 4731 N N . VAL B 1 102 ? -9.311 0.820 -38.245 1.00 44.08 ? 102 VAL B N 1 ATOM 4732 C CA . VAL B 1 102 ? -10.768 0.662 -38.212 1.00 43.11 ? 102 VAL B CA 1 ATOM 4733 C C . VAL B 1 102 ? -11.553 1.939 -38.572 1.00 42.97 ? 102 VAL B C 1 ATOM 4734 O O . VAL B 1 102 ? -12.527 1.871 -39.322 1.00 42.68 ? 102 VAL B O 1 ATOM 4735 C CB . VAL B 1 102 ? -11.240 0.009 -36.878 1.00 42.91 ? 102 VAL B CB 1 ATOM 4736 C CG1 . VAL B 1 102 ? -12.758 0.014 -36.747 1.00 41.89 ? 102 VAL B CG1 1 ATOM 4737 C CG2 . VAL B 1 102 ? -10.711 -1.409 -36.780 1.00 42.10 ? 102 VAL B CG2 1 ATOM 4738 N N . THR B 1 103 ? -11.128 3.095 -38.068 1.00 42.90 ? 103 THR B N 1 ATOM 4739 C CA . THR B 1 103 ? -11.823 4.362 -38.377 1.00 43.04 ? 103 THR B CA 1 ATOM 4740 C C . THR B 1 103 ? -11.645 4.779 -39.839 1.00 42.97 ? 103 THR B C 1 ATOM 4741 O O . THR B 1 103 ? -12.349 5.662 -40.328 1.00 42.96 ? 103 THR B O 1 ATOM 4742 C CB . THR B 1 103 ? -11.363 5.548 -37.492 1.00 42.90 ? 103 THR B CB 1 ATOM 4743 O OG1 . THR B 1 103 ? -10.721 5.069 -36.312 1.00 43.74 ? 103 THR B OG1 1 ATOM 4744 C CG2 . THR B 1 103 ? -12.545 6.377 -37.079 1.00 43.39 ? 103 THR B CG2 1 ATOM 4745 N N . TYR B 1 104 ? -10.700 4.143 -40.526 1.00 43.07 ? 104 TYR B N 1 ATOM 4746 C CA . TYR B 1 104 ? -10.445 4.425 -41.935 1.00 43.39 ? 104 TYR B CA 1 ATOM 4747 C C . TYR B 1 104 ? -11.206 3.505 -42.886 1.00 43.34 ? 104 TYR B C 1 ATOM 4748 O O . TYR B 1 104 ? -11.096 3.645 -44.108 1.00 43.65 ? 104 TYR B O 1 ATOM 4749 C CB . TYR B 1 104 ? -8.947 4.381 -42.231 1.00 43.43 ? 104 TYR B CB 1 ATOM 4750 C CG . TYR B 1 104 ? -8.256 5.689 -41.945 1.00 44.48 ? 104 TYR B CG 1 ATOM 4751 C CD1 . TYR B 1 104 ? -7.669 5.935 -40.703 1.00 45.27 ? 104 TYR B CD1 1 ATOM 4752 C CD2 . TYR B 1 104 ? -8.200 6.690 -42.912 1.00 45.43 ? 104 TYR B CD2 1 ATOM 4753 C CE1 . TYR B 1 104 ? -7.034 7.140 -40.436 1.00 46.04 ? 104 TYR B CE1 1 ATOM 4754 C CE2 . TYR B 1 104 ? -7.568 7.903 -42.655 1.00 45.93 ? 104 TYR B CE2 1 ATOM 4755 C CZ . TYR B 1 104 ? -6.988 8.120 -41.416 1.00 46.07 ? 104 TYR B CZ 1 ATOM 4756 O OH . TYR B 1 104 ? -6.367 9.317 -41.156 1.00 45.77 ? 104 TYR B OH 1 ATOM 4757 N N . ARG B 1 105 ? -11.975 2.574 -42.324 1.00 43.15 ? 105 ARG B N 1 ATOM 4758 C CA . ARG B 1 105 ? -12.768 1.638 -43.111 1.00 42.83 ? 105 ARG B CA 1 ATOM 4759 C C . ARG B 1 105 ? -14.057 2.301 -43.575 1.00 43.12 ? 105 ARG B C 1 ATOM 4760 O O . ARG B 1 105 ? -14.612 3.134 -42.863 1.00 43.15 ? 105 ARG B O 1 ATOM 4761 C CB . ARG B 1 105 ? -13.081 0.378 -42.304 1.00 42.51 ? 105 ARG B CB 1 ATOM 4762 C CG . ARG B 1 105 ? -11.858 -0.424 -41.914 1.00 41.00 ? 105 ARG B CG 1 ATOM 4763 C CD . ARG B 1 105 ? -12.242 -1.609 -41.065 1.00 39.16 ? 105 ARG B CD 1 ATOM 4764 N NE . ARG B 1 105 ? -11.083 -2.426 -40.724 1.00 38.07 ? 105 ARG B NE 1 ATOM 4765 C CZ . ARG B 1 105 ? -11.140 -3.731 -40.470 1.00 37.70 ? 105 ARG B CZ 1 ATOM 4766 N NH1 . ARG B 1 105 ? -12.300 -4.375 -40.535 1.00 36.38 ? 105 ARG B NH1 1 ATOM 4767 N NH2 . ARG B 1 105 ? -10.031 -4.397 -40.167 1.00 38.15 ? 105 ARG B NH2 1 ATOM 4768 N N . PRO B 1 106 ? -14.528 1.942 -44.780 1.00 43.49 ? 106 PRO B N 1 ATOM 4769 C CA . PRO B 1 106 ? -15.748 2.513 -45.357 1.00 43.88 ? 106 PRO B CA 1 ATOM 4770 C C . PRO B 1 106 ? -16.940 2.480 -44.407 1.00 44.37 ? 106 PRO B C 1 ATOM 4771 O O . PRO B 1 106 ? -17.092 1.529 -43.643 1.00 44.42 ? 106 PRO B O 1 ATOM 4772 C CB . PRO B 1 106 ? -16.031 1.614 -46.571 1.00 43.71 ? 106 PRO B CB 1 ATOM 4773 C CG . PRO B 1 106 ? -14.936 0.569 -46.597 1.00 43.68 ? 106 PRO B CG 1 ATOM 4774 C CD . PRO B 1 106 ? -13.830 1.068 -45.738 1.00 43.55 ? 106 PRO B CD 1 ATOM 4775 N N . HIS B 1 107 ? -17.757 3.533 -44.464 1.00 44.99 ? 107 HIS B N 1 ATOM 4776 C CA . HIS B 1 107 ? -19.057 3.618 -43.786 1.00 45.66 ? 107 HIS B CA 1 ATOM 4777 C C . HIS B 1 107 ? -18.984 3.929 -42.291 1.00 46.00 ? 107 HIS B C 1 ATOM 4778 O O . HIS B 1 107 ? -19.998 3.837 -41.587 1.00 46.04 ? 107 HIS B O 1 ATOM 4779 C CB . HIS B 1 107 ? -19.907 2.358 -44.031 1.00 45.94 ? 107 HIS B CB 1 ATOM 4780 C CG . HIS B 1 107 ? -19.964 1.931 -45.465 1.00 46.94 ? 107 HIS B CG 1 ATOM 4781 N ND1 . HIS B 1 107 ? -20.488 2.729 -46.460 1.00 48.53 ? 107 HIS B ND1 1 ATOM 4782 C CD2 . HIS B 1 107 ? -19.566 0.788 -46.070 1.00 47.16 ? 107 HIS B CD2 1 ATOM 4783 C CE1 . HIS B 1 107 ? -20.404 2.097 -47.617 1.00 48.74 ? 107 HIS B CE1 1 ATOM 4784 N NE2 . HIS B 1 107 ? -19.849 0.917 -47.407 1.00 48.53 ? 107 HIS B NE2 1 ATOM 4785 N N . CYS B 1 108 ? -17.797 4.304 -41.815 1.00 46.34 ? 108 CYS B N 1 ATOM 4786 C CA . CYS B 1 108 ? -17.599 4.689 -40.418 1.00 46.74 ? 108 CYS B CA 1 ATOM 4787 C C . CYS B 1 108 ? -18.186 6.075 -40.149 1.00 47.00 ? 108 CYS B C 1 ATOM 4788 O O . CYS B 1 108 ? -17.829 7.043 -40.821 1.00 46.91 ? 108 CYS B O 1 ATOM 4789 C CB . CYS B 1 108 ? -16.109 4.670 -40.070 1.00 46.82 ? 108 CYS B CB 1 ATOM 4790 S SG . CYS B 1 108 ? -15.769 4.474 -38.311 1.00 47.32 ? 108 CYS B SG 1 ATOM 4791 N N . HIS B 1 109 ? -19.103 6.159 -39.187 1.00 47.38 ? 109 HIS B N 1 ATOM 4792 C CA . HIS B 1 109 ? -19.714 7.431 -38.803 1.00 48.00 ? 109 HIS B CA 1 ATOM 4793 C C . HIS B 1 109 ? -19.339 7.800 -37.379 1.00 48.55 ? 109 HIS B C 1 ATOM 4794 O O . HIS B 1 109 ? -19.182 6.926 -36.522 1.00 48.59 ? 109 HIS B O 1 ATOM 4795 C CB . HIS B 1 109 ? -21.237 7.375 -38.912 1.00 47.85 ? 109 HIS B CB 1 ATOM 4796 C CG . HIS B 1 109 ? -21.743 7.290 -40.315 1.00 48.25 ? 109 HIS B CG 1 ATOM 4797 N ND1 . HIS B 1 109 ? -21.706 6.125 -41.050 1.00 48.67 ? 109 HIS B ND1 1 ATOM 4798 C CD2 . HIS B 1 109 ? -22.315 8.222 -41.113 1.00 48.41 ? 109 HIS B CD2 1 ATOM 4799 C CE1 . HIS B 1 109 ? -22.230 6.345 -42.243 1.00 49.40 ? 109 HIS B CE1 1 ATOM 4800 N NE2 . HIS B 1 109 ? -22.604 7.610 -42.308 1.00 48.82 ? 109 HIS B NE2 1 ATOM 4801 N N . ILE B 1 110 ? -19.206 9.100 -37.131 1.00 49.19 ? 110 ILE B N 1 ATOM 4802 C CA . ILE B 1 110 ? -18.924 9.611 -35.793 1.00 49.71 ? 110 ILE B CA 1 ATOM 4803 C C . ILE B 1 110 ? -20.060 10.495 -35.317 1.00 50.27 ? 110 ILE B C 1 ATOM 4804 O O . ILE B 1 110 ? -20.779 11.080 -36.126 1.00 50.25 ? 110 ILE B O 1 ATOM 4805 C CB . ILE B 1 110 ? -17.569 10.376 -35.729 1.00 49.70 ? 110 ILE B CB 1 ATOM 4806 C CG1 . ILE B 1 110 ? -17.154 10.627 -34.270 1.00 49.52 ? 110 ILE B CG1 1 ATOM 4807 C CG2 . ILE B 1 110 ? -17.618 11.671 -36.558 1.00 49.44 ? 110 ILE B CG2 1 ATOM 4808 C CD1 . ILE B 1 110 ? -15.684 10.957 -34.080 1.00 49.15 ? 110 ILE B CD1 1 ATOM 4809 N N . CYS B 1 111 ? -20.214 10.580 -34.001 1.00 51.21 ? 111 CYS B N 1 ATOM 4810 C CA . CYS B 1 111 ? -21.231 11.421 -33.392 1.00 52.20 ? 111 CYS B CA 1 ATOM 4811 C C . CYS B 1 111 ? -20.844 11.862 -31.984 1.00 52.19 ? 111 CYS B C 1 ATOM 4812 O O . CYS B 1 111 ? -19.865 11.375 -31.416 1.00 52.13 ? 111 CYS B O 1 ATOM 4813 C CB . CYS B 1 111 ? -22.563 10.688 -33.356 1.00 52.60 ? 111 CYS B CB 1 ATOM 4814 S SG . CYS B 1 111 ? -23.853 11.653 -32.620 1.00 55.36 ? 111 CYS B SG 1 ATOM 4815 N N . PHE B 1 112 ? -21.623 12.797 -31.441 1.00 52.48 ? 112 PHE B N 1 ATOM 4816 C CA . PHE B 1 112 ? -21.471 13.274 -30.068 1.00 52.58 ? 112 PHE B CA 1 ATOM 4817 C C . PHE B 1 112 ? -22.826 13.410 -29.384 1.00 53.12 ? 112 PHE B C 1 ATOM 4818 O O . PHE B 1 112 ? -23.707 14.119 -29.874 1.00 53.18 ? 112 PHE B O 1 ATOM 4819 C CB . PHE B 1 112 ? -20.741 14.614 -30.044 1.00 52.33 ? 112 PHE B CB 1 ATOM 4820 C CG . PHE B 1 112 ? -19.319 14.537 -30.518 1.00 51.47 ? 112 PHE B CG 1 ATOM 4821 C CD1 . PHE B 1 112 ? -18.297 14.182 -29.639 1.00 51.15 ? 112 PHE B CD1 1 ATOM 4822 C CD2 . PHE B 1 112 ? -18.996 14.821 -31.840 1.00 50.52 ? 112 PHE B CD2 1 ATOM 4823 C CE1 . PHE B 1 112 ? -16.966 14.108 -30.077 1.00 50.70 ? 112 PHE B CE1 1 ATOM 4824 C CE2 . PHE B 1 112 ? -17.676 14.748 -32.288 1.00 50.27 ? 112 PHE B CE2 1 ATOM 4825 C CZ . PHE B 1 112 ? -16.659 14.391 -31.404 1.00 50.28 ? 112 PHE B CZ 1 ATOM 4826 N N . THR B 1 113 ? -22.976 12.723 -28.253 1.00 53.89 ? 113 THR B N 1 ATOM 4827 C CA . THR B 1 113 ? -24.183 12.765 -27.419 1.00 54.72 ? 113 THR B CA 1 ATOM 4828 C C . THR B 1 113 ? -24.499 14.199 -26.996 1.00 55.14 ? 113 THR B C 1 ATOM 4829 O O . THR B 1 113 ? -23.597 15.044 -26.975 1.00 55.30 ? 113 THR B O 1 ATOM 4830 C CB . THR B 1 113 ? -23.980 11.958 -26.119 1.00 54.72 ? 113 THR B CB 1 ATOM 4831 O OG1 . THR B 1 113 ? -22.733 11.260 -26.170 1.00 55.43 ? 113 THR B OG1 1 ATOM 4832 C CG2 . THR B 1 113 ? -25.111 10.969 -25.909 1.00 54.95 ? 113 THR B CG2 1 ATOM 4833 N N . PRO B 1 114 ? -25.773 14.488 -26.655 1.00 55.55 ? 114 PRO B N 1 ATOM 4834 C CA . PRO B 1 114 ? -26.067 15.783 -26.041 1.00 55.74 ? 114 PRO B CA 1 ATOM 4835 C C . PRO B 1 114 ? -24.968 16.238 -25.070 1.00 55.85 ? 114 PRO B C 1 ATOM 4836 O O . PRO B 1 114 ? -24.654 17.428 -25.007 1.00 56.01 ? 114 PRO B O 1 ATOM 4837 C CB . PRO B 1 114 ? -27.373 15.516 -25.279 1.00 55.88 ? 114 PRO B CB 1 ATOM 4838 C CG . PRO B 1 114 ? -27.994 14.262 -25.942 1.00 55.78 ? 114 PRO B CG 1 ATOM 4839 C CD . PRO B 1 114 ? -27.012 13.750 -26.971 1.00 55.68 ? 114 PRO B CD 1 ATOM 4840 N N . ARG B 1 115 ? -24.374 15.290 -24.348 1.00 55.77 ? 115 ARG B N 1 ATOM 4841 C CA . ARG B 1 115 ? -23.344 15.597 -23.358 1.00 55.67 ? 115 ARG B CA 1 ATOM 4842 C C . ARG B 1 115 ? -21.938 15.790 -23.897 1.00 54.71 ? 115 ARG B C 1 ATOM 4843 O O . ARG B 1 115 ? -21.070 16.284 -23.181 1.00 54.81 ? 115 ARG B O 1 ATOM 4844 C CB . ARG B 1 115 ? -23.307 14.531 -22.277 1.00 56.21 ? 115 ARG B CB 1 ATOM 4845 C CG . ARG B 1 115 ? -24.019 14.961 -21.035 1.00 58.99 ? 115 ARG B CG 1 ATOM 4846 C CD . ARG B 1 115 ? -23.788 13.976 -19.915 1.00 63.79 ? 115 ARG B CD 1 ATOM 4847 N NE . ARG B 1 115 ? -24.963 13.908 -19.053 1.00 67.43 ? 115 ARG B NE 1 ATOM 4848 C CZ . ARG B 1 115 ? -26.108 13.310 -19.388 1.00 69.20 ? 115 ARG B CZ 1 ATOM 4849 N NH1 . ARG B 1 115 ? -26.245 12.723 -20.572 1.00 70.27 ? 115 ARG B NH1 1 ATOM 4850 N NH2 . ARG B 1 115 ? -27.125 13.299 -18.538 1.00 69.79 ? 115 ARG B NH2 1 ATOM 4851 N N . GLY B 1 116 ? -21.708 15.395 -25.144 1.00 53.66 ? 116 GLY B N 1 ATOM 4852 C CA . GLY B 1 116 ? -20.390 15.534 -25.756 1.00 51.91 ? 116 GLY B CA 1 ATOM 4853 C C . GLY B 1 116 ? -19.546 14.271 -25.722 1.00 50.67 ? 116 GLY B C 1 ATOM 4854 O O . GLY B 1 116 ? -18.353 14.317 -26.022 1.00 50.74 ? 116 GLY B O 1 ATOM 4855 N N . ILE B 1 117 ? -20.155 13.143 -25.360 1.00 49.20 ? 117 ILE B N 1 ATOM 4856 C CA . ILE B 1 117 ? -19.464 11.855 -25.427 1.00 47.80 ? 117 ILE B CA 1 ATOM 4857 C C . ILE B 1 117 ? -19.389 11.363 -26.875 1.00 46.78 ? 117 ILE B C 1 ATOM 4858 O O . ILE B 1 117 ? -20.405 11.263 -27.570 1.00 46.51 ? 117 ILE B O 1 ATOM 4859 C CB . ILE B 1 117 ? -20.130 10.761 -24.545 1.00 47.85 ? 117 ILE B CB 1 ATOM 4860 C CG1 . ILE B 1 117 ? -20.298 11.243 -23.100 1.00 48.05 ? 117 ILE B CG1 1 ATOM 4861 C CG2 . ILE B 1 117 ? -19.322 9.458 -24.599 1.00 47.50 ? 117 ILE B CG2 1 ATOM 4862 C CD1 . ILE B 1 117 ? -21.281 10.413 -22.278 1.00 48.47 ? 117 ILE B CD1 1 ATOM 4863 N N . MET B 1 118 ? -18.171 11.060 -27.307 1.00 45.51 ? 118 MET B N 1 ATOM 4864 C CA . MET B 1 118 ? -17.910 10.485 -28.617 1.00 44.62 ? 118 MET B CA 1 ATOM 4865 C C . MET B 1 118 ? -18.555 9.105 -28.760 1.00 44.13 ? 118 MET B C 1 ATOM 4866 O O . MET B 1 118 ? -18.755 8.394 -27.775 1.00 43.93 ? 118 MET B O 1 ATOM 4867 C CB . MET B 1 118 ? -16.405 10.385 -28.836 1.00 44.42 ? 118 MET B CB 1 ATOM 4868 C CG . MET B 1 118 ? -15.982 10.185 -30.272 1.00 44.25 ? 118 MET B CG 1 ATOM 4869 S SD . MET B 1 118 ? -14.271 10.703 -30.507 1.00 45.33 ? 118 MET B SD 1 ATOM 4870 C CE . MET B 1 118 ? -13.402 9.456 -29.591 1.00 44.15 ? 118 MET B CE 1 ATOM 4871 N N . GLN B 1 119 ? -18.872 8.738 -29.999 1.00 43.52 ? 119 GLN B N 1 ATOM 4872 C CA . GLN B 1 119 ? -19.586 7.502 -30.284 1.00 43.01 ? 119 GLN B CA 1 ATOM 4873 C C . GLN B 1 119 ? -19.537 7.188 -31.781 1.00 42.35 ? 119 GLN B C 1 ATOM 4874 O O . GLN B 1 119 ? -19.450 8.089 -32.613 1.00 42.25 ? 119 GLN B O 1 ATOM 4875 C CB . GLN B 1 119 ? -21.001 7.608 -29.704 1.00 43.03 ? 119 GLN B CB 1 ATOM 4876 C CG . GLN B 1 119 ? -22.137 7.090 -30.518 1.00 44.50 ? 119 GLN B CG 1 ATOM 4877 C CD . GLN B 1 119 ? -23.454 7.541 -29.940 1.00 47.34 ? 119 GLN B CD 1 ATOM 4878 O OE1 . GLN B 1 119 ? -23.751 8.761 -29.996 1.00 48.20 ? 119 GLN B OE1 1 ATOM 4879 N NE2 . GLN B 1 119 ? -24.186 6.673 -29.415 1.00 48.82 ? 119 GLN B NE2 1 ATOM 4880 N N . PHE B 1 120 ? -19.557 5.902 -32.114 1.00 41.94 ? 120 PHE B N 1 ATOM 4881 C CA . PHE B 1 120 ? -19.333 5.455 -33.490 1.00 41.37 ? 120 PHE B CA 1 ATOM 4882 C C . PHE B 1 120 ? -20.384 4.482 -33.986 1.00 41.31 ? 120 PHE B C 1 ATOM 4883 O O . PHE B 1 120 ? -21.025 3.785 -33.193 1.00 41.06 ? 120 PHE B O 1 ATOM 4884 C CB . PHE B 1 120 ? -17.957 4.808 -33.621 1.00 41.27 ? 120 PHE B CB 1 ATOM 4885 C CG . PHE B 1 120 ? -16.818 5.764 -33.444 1.00 40.93 ? 120 PHE B CG 1 ATOM 4886 C CD1 . PHE B 1 120 ? -16.212 6.352 -34.549 1.00 40.11 ? 120 PHE B CD1 1 ATOM 4887 C CD2 . PHE B 1 120 ? -16.340 6.074 -32.167 1.00 40.98 ? 120 PHE B CD2 1 ATOM 4888 C CE1 . PHE B 1 120 ? -15.151 7.240 -34.386 1.00 40.22 ? 120 PHE B CE1 1 ATOM 4889 C CE2 . PHE B 1 120 ? -15.279 6.960 -31.995 1.00 40.44 ? 120 PHE B CE2 1 ATOM 4890 C CZ . PHE B 1 120 ? -14.682 7.542 -33.106 1.00 40.11 ? 120 PHE B CZ 1 ATOM 4891 N N . ARG B 1 121 ? -20.557 4.454 -35.307 1.00 41.44 ? 121 ARG B N 1 ATOM 4892 C CA . ARG B 1 121 ? -21.410 3.473 -35.956 1.00 42.04 ? 121 ARG B CA 1 ATOM 4893 C C . ARG B 1 121 ? -21.052 3.268 -37.424 1.00 41.78 ? 121 ARG B C 1 ATOM 4894 O O . ARG B 1 121 ? -20.875 4.230 -38.164 1.00 41.64 ? 121 ARG B O 1 ATOM 4895 C CB . ARG B 1 121 ? -22.902 3.808 -35.819 1.00 42.26 ? 121 ARG B CB 1 ATOM 4896 C CG . ARG B 1 121 ? -23.716 2.640 -36.319 1.00 45.24 ? 121 ARG B CG 1 ATOM 4897 C CD . ARG B 1 121 ? -25.167 2.673 -36.098 1.00 51.44 ? 121 ARG B CD 1 ATOM 4898 N NE . ARG B 1 121 ? -25.723 2.139 -34.852 1.00 56.55 ? 121 ARG B NE 1 ATOM 4899 C CZ . ARG B 1 121 ? -25.753 2.786 -33.689 1.00 59.36 ? 121 ARG B CZ 1 ATOM 4900 N NH1 . ARG B 1 121 ? -25.165 3.965 -33.548 1.00 60.91 ? 121 ARG B NH1 1 ATOM 4901 N NH2 . ARG B 1 121 ? -26.348 2.236 -32.644 1.00 61.08 ? 121 ARG B NH2 1 ATOM 4902 N N . PHE B 1 122 ? -20.933 2.007 -37.830 1.00 41.79 ? 122 PHE B N 1 ATOM 4903 C CA . PHE B 1 122 ? -20.844 1.664 -39.238 1.00 41.83 ? 122 PHE B CA 1 ATOM 4904 C C . PHE B 1 122 ? -22.249 1.477 -39.791 1.00 42.69 ? 122 PHE B C 1 ATOM 4905 O O . PHE B 1 122 ? -23.027 0.675 -39.259 1.00 42.67 ? 122 PHE B O 1 ATOM 4906 C CB . PHE B 1 122 ? -20.033 0.390 -39.428 1.00 41.23 ? 122 PHE B CB 1 ATOM 4907 C CG . PHE B 1 122 ? -18.564 0.585 -39.265 1.00 39.43 ? 122 PHE B CG 1 ATOM 4908 C CD1 . PHE B 1 122 ? -17.960 0.406 -38.027 1.00 37.61 ? 122 PHE B CD1 1 ATOM 4909 C CD2 . PHE B 1 122 ? -17.777 0.943 -40.355 1.00 38.18 ? 122 PHE B CD2 1 ATOM 4910 C CE1 . PHE B 1 122 ? -16.588 0.577 -37.870 1.00 37.38 ? 122 PHE B CE1 1 ATOM 4911 C CE2 . PHE B 1 122 ? -16.400 1.123 -40.210 1.00 38.06 ? 122 PHE B CE2 1 ATOM 4912 C CZ . PHE B 1 122 ? -15.803 0.936 -38.964 1.00 37.54 ? 122 PHE B CZ 1 ATOM 4913 N N . ALA B 1 123 ? -22.570 2.227 -40.846 1.00 43.76 ? 123 ALA B N 1 ATOM 4914 C CA . ALA B 1 123 ? -23.898 2.195 -41.470 1.00 45.14 ? 123 ALA B CA 1 ATOM 4915 C C . ALA B 1 123 ? -23.889 2.730 -42.903 1.00 46.18 ? 123 ALA B C 1 ATOM 4916 O O . ALA B 1 123 ? -22.991 3.474 -43.292 1.00 46.23 ? 123 ALA B O 1 ATOM 4917 C CB . ALA B 1 123 ? -24.908 2.979 -40.628 1.00 44.74 ? 123 ALA B CB 1 ATOM 4918 N N . HIS B 1 124 ? -24.902 2.350 -43.676 1.00 47.67 ? 124 HIS B N 1 ATOM 4919 C CA . HIS B 1 124 ? -25.149 2.919 -44.997 1.00 49.22 ? 124 HIS B CA 1 ATOM 4920 C C . HIS B 1 124 ? -26.652 2.867 -45.263 1.00 50.19 ? 124 HIS B C 1 ATOM 4921 O O . HIS B 1 124 ? -27.250 1.796 -45.223 1.00 50.27 ? 124 HIS B O 1 ATOM 4922 C CB . HIS B 1 124 ? -24.369 2.178 -46.090 1.00 49.21 ? 124 HIS B CB 1 ATOM 4923 C CG . HIS B 1 124 ? -24.441 2.831 -47.439 1.00 50.18 ? 124 HIS B CG 1 ATOM 4924 N ND1 . HIS B 1 124 ? -23.352 3.430 -48.036 1.00 50.89 ? 124 HIS B ND1 1 ATOM 4925 C CD2 . HIS B 1 124 ? -25.472 2.978 -48.307 1.00 50.25 ? 124 HIS B CD2 1 ATOM 4926 C CE1 . HIS B 1 124 ? -23.707 3.912 -49.215 1.00 50.20 ? 124 HIS B CE1 1 ATOM 4927 N NE2 . HIS B 1 124 ? -24.989 3.653 -49.401 1.00 50.31 ? 124 HIS B NE2 1 ATOM 4928 N N . PRO B 1 125 ? -27.275 4.030 -45.506 1.00 51.40 ? 125 PRO B N 1 ATOM 4929 C CA . PRO B 1 125 ? -26.623 5.339 -45.521 1.00 52.35 ? 125 PRO B CA 1 ATOM 4930 C C . PRO B 1 125 ? -26.490 5.918 -44.105 1.00 53.24 ? 125 PRO B C 1 ATOM 4931 O O . PRO B 1 125 ? -26.735 5.209 -43.123 1.00 53.34 ? 125 PRO B O 1 ATOM 4932 C CB . PRO B 1 125 ? -27.577 6.179 -46.375 1.00 52.24 ? 125 PRO B CB 1 ATOM 4933 C CG . PRO B 1 125 ? -28.937 5.572 -46.126 1.00 51.94 ? 125 PRO B CG 1 ATOM 4934 C CD . PRO B 1 125 ? -28.737 4.142 -45.681 1.00 51.44 ? 125 PRO B CD 1 ATOM 4935 N N . THR B 1 126 ? -26.105 7.187 -44.008 1.00 54.52 ? 126 THR B N 1 ATOM 4936 C CA . THR B 1 126 ? -26.011 7.885 -42.722 1.00 55.76 ? 126 THR B CA 1 ATOM 4937 C C . THR B 1 126 ? -27.245 7.646 -41.845 1.00 56.79 ? 126 THR B C 1 ATOM 4938 O O . THR B 1 126 ? -28.369 7.893 -42.281 1.00 56.80 ? 126 THR B O 1 ATOM 4939 C CB . THR B 1 126 ? -25.765 9.406 -42.913 1.00 55.64 ? 126 THR B CB 1 ATOM 4940 O OG1 . THR B 1 126 ? -24.518 9.605 -43.591 1.00 55.55 ? 126 THR B OG1 1 ATOM 4941 C CG2 . THR B 1 126 ? -25.725 10.143 -41.566 1.00 55.49 ? 126 THR B CG2 1 ATOM 4942 N N . PRO B 1 127 ? -27.031 7.142 -40.611 1.00 57.96 ? 127 PRO B N 1 ATOM 4943 C CA . PRO B 1 127 ? -28.108 6.895 -39.654 1.00 58.99 ? 127 PRO B CA 1 ATOM 4944 C C . PRO B 1 127 ? -29.036 8.097 -39.461 1.00 60.16 ? 127 PRO B C 1 ATOM 4945 O O . PRO B 1 127 ? -28.657 9.238 -39.747 1.00 60.19 ? 127 PRO B O 1 ATOM 4946 C CB . PRO B 1 127 ? -27.356 6.601 -38.354 1.00 58.89 ? 127 PRO B CB 1 ATOM 4947 C CG . PRO B 1 127 ? -26.057 6.047 -38.784 1.00 58.40 ? 127 PRO B CG 1 ATOM 4948 C CD . PRO B 1 127 ? -25.722 6.695 -40.092 1.00 57.95 ? 127 PRO B CD 1 ATOM 4949 N N . ARG B 1 128 ? -30.247 7.824 -38.985 1.00 61.53 ? 128 ARG B N 1 ATOM 4950 C CA . ARG B 1 128 ? -31.236 8.865 -38.725 1.00 62.86 ? 128 ARG B CA 1 ATOM 4951 C C . ARG B 1 128 ? -30.960 9.499 -37.358 1.00 63.35 ? 128 ARG B C 1 ATOM 4952 O O . ARG B 1 128 ? -30.743 8.780 -36.377 1.00 63.33 ? 128 ARG B O 1 ATOM 4953 C CB . ARG B 1 128 ? -32.662 8.289 -38.782 1.00 63.13 ? 128 ARG B CB 1 ATOM 4954 C CG . ARG B 1 128 ? -32.968 7.434 -40.026 1.00 64.20 ? 128 ARG B CG 1 ATOM 4955 C CD . ARG B 1 128 ? -34.471 7.283 -40.271 1.00 66.44 ? 128 ARG B CD 1 ATOM 4956 N NE . ARG B 1 128 ? -35.079 8.519 -40.776 1.00 68.09 ? 128 ARG B NE 1 ATOM 4957 C CZ . ARG B 1 128 ? -35.810 9.368 -40.049 1.00 68.53 ? 128 ARG B CZ 1 ATOM 4958 N NH1 . ARG B 1 128 ? -36.047 9.131 -38.765 1.00 68.71 ? 128 ARG B NH1 1 ATOM 4959 N NH2 . ARG B 1 128 ? -36.307 10.461 -40.612 1.00 68.41 ? 128 ARG B NH2 1 ATOM 4960 N N . PRO B 1 129 ? -30.951 10.846 -37.291 1.00 63.88 ? 129 PRO B N 1 ATOM 4961 C CA . PRO B 1 129 ? -30.726 11.542 -36.019 1.00 64.36 ? 129 PRO B CA 1 ATOM 4962 C C . PRO B 1 129 ? -31.661 11.022 -34.924 1.00 64.80 ? 129 PRO B C 1 ATOM 4963 O O . PRO B 1 129 ? -32.878 11.126 -35.057 1.00 64.98 ? 129 PRO B O 1 ATOM 4964 C CB . PRO B 1 129 ? -31.047 13.001 -36.357 1.00 64.33 ? 129 PRO B CB 1 ATOM 4965 C CG . PRO B 1 129 ? -30.757 13.117 -37.817 1.00 64.26 ? 129 PRO B CG 1 ATOM 4966 C CD . PRO B 1 129 ? -31.143 11.789 -38.410 1.00 63.95 ? 129 PRO B CD 1 ATOM 4967 N N . SER B 1 130 ? -31.090 10.438 -33.874 1.00 65.25 ? 130 SER B N 1 ATOM 4968 C CA . SER B 1 130 ? -31.875 9.880 -32.778 1.00 65.72 ? 130 SER B CA 1 ATOM 4969 C C . SER B 1 130 ? -31.685 10.684 -31.495 1.00 66.01 ? 130 SER B C 1 ATOM 4970 O O . SER B 1 130 ? -30.986 11.701 -31.483 1.00 66.08 ? 130 SER B O 1 ATOM 4971 C CB . SER B 1 130 ? -31.515 8.412 -32.547 1.00 65.74 ? 130 SER B CB 1 ATOM 4972 O OG . SER B 1 130 ? -30.228 8.288 -31.969 1.00 66.14 ? 130 SER B OG 1 ATOM 4973 N N . GLU B 1 131 ? -32.308 10.224 -30.415 1.00 66.30 ? 131 GLU B N 1 ATOM 4974 C CA . GLU B 1 131 ? -32.268 10.948 -29.148 1.00 66.70 ? 131 GLU B CA 1 ATOM 4975 C C . GLU B 1 131 ? -31.055 10.558 -28.302 1.00 66.46 ? 131 GLU B C 1 ATOM 4976 O O . GLU B 1 131 ? -31.185 10.223 -27.122 1.00 66.71 ? 131 GLU B O 1 ATOM 4977 C CB . GLU B 1 131 ? -33.582 10.762 -28.384 1.00 66.89 ? 131 GLU B CB 1 ATOM 4978 C CG . GLU B 1 131 ? -34.775 11.427 -29.069 1.00 68.27 ? 131 GLU B CG 1 ATOM 4979 C CD . GLU B 1 131 ? -36.118 10.962 -28.529 1.00 70.13 ? 131 GLU B CD 1 ATOM 4980 O OE1 . GLU B 1 131 ? -36.213 9.812 -28.039 1.00 70.79 ? 131 GLU B OE1 1 ATOM 4981 O OE2 . GLU B 1 131 ? -37.087 11.750 -28.605 1.00 70.67 ? 131 GLU B OE2 1 ATOM 4982 N N . LYS B 1 132 ? -29.884 10.604 -28.937 1.00 66.01 ? 132 LYS B N 1 ATOM 4983 C CA . LYS B 1 132 ? -28.583 10.305 -28.325 1.00 65.53 ? 132 LYS B CA 1 ATOM 4984 C C . LYS B 1 132 ? -27.503 10.791 -29.288 1.00 64.87 ? 132 LYS B C 1 ATOM 4985 O O . LYS B 1 132 ? -26.299 10.637 -29.037 1.00 64.86 ? 132 LYS B O 1 ATOM 4986 C CB . LYS B 1 132 ? -28.415 8.799 -28.071 1.00 65.74 ? 132 LYS B CB 1 ATOM 4987 C CG . LYS B 1 132 ? -28.754 8.331 -26.648 1.00 66.50 ? 132 LYS B CG 1 ATOM 4988 C CD . LYS B 1 132 ? -27.590 8.546 -25.674 1.00 67.60 ? 132 LYS B CD 1 ATOM 4989 C CE . LYS B 1 132 ? -27.859 7.904 -24.313 1.00 68.15 ? 132 LYS B CE 1 ATOM 4990 N NZ . LYS B 1 132 ? -26.619 7.792 -23.485 1.00 68.28 ? 132 LYS B NZ 1 ATOM 4991 N N . CYS B 1 133 ? -27.959 11.375 -30.395 1.00 63.80 ? 133 CYS B N 1 ATOM 4992 C CA . CYS B 1 133 ? -27.095 11.806 -31.480 1.00 62.71 ? 133 CYS B CA 1 ATOM 4993 C C . CYS B 1 133 ? -27.835 12.749 -32.426 1.00 62.50 ? 133 CYS B C 1 ATOM 4994 O O . CYS B 1 133 ? -28.622 12.301 -33.269 1.00 62.47 ? 133 CYS B O 1 ATOM 4995 C CB . CYS B 1 133 ? -26.601 10.593 -32.261 1.00 62.32 ? 133 CYS B CB 1 ATOM 4996 S SG . CYS B 1 133 ? -25.523 11.058 -33.596 1.00 60.77 ? 133 CYS B SG 1 ATOM 4997 N N . SER B 1 134 ? -27.575 14.049 -32.296 1.00 62.04 ? 134 SER B N 1 ATOM 4998 C CA . SER B 1 134 ? -28.285 15.052 -33.101 1.00 61.63 ? 134 SER B CA 1 ATOM 4999 C C . SER B 1 134 ? -27.938 14.962 -34.593 1.00 61.15 ? 134 SER B C 1 ATOM 5000 O O . SER B 1 134 ? -28.793 15.216 -35.442 1.00 61.12 ? 134 SER B O 1 ATOM 5001 C CB . SER B 1 134 ? -28.065 16.470 -32.560 1.00 61.65 ? 134 SER B CB 1 ATOM 5002 O OG . SER B 1 134 ? -26.726 16.892 -32.746 1.00 61.86 ? 134 SER B OG 1 ATOM 5003 N N . LYS B 1 135 ? -26.692 14.601 -34.896 1.00 60.46 ? 135 LYS B N 1 ATOM 5004 C CA . LYS B 1 135 ? -26.266 14.333 -36.268 1.00 59.98 ? 135 LYS B CA 1 ATOM 5005 C C . LYS B 1 135 ? -25.100 13.360 -36.340 1.00 59.30 ? 135 LYS B C 1 ATOM 5006 O O . LYS B 1 135 ? -24.141 13.467 -35.575 1.00 59.25 ? 135 LYS B O 1 ATOM 5007 C CB . LYS B 1 135 ? -25.907 15.628 -37.016 1.00 60.33 ? 135 LYS B CB 1 ATOM 5008 C CG . LYS B 1 135 ? -26.964 16.093 -38.038 1.00 61.27 ? 135 LYS B CG 1 ATOM 5009 C CD . LYS B 1 135 ? -26.965 15.221 -39.299 1.00 62.91 ? 135 LYS B CD 1 ATOM 5010 C CE . LYS B 1 135 ? -28.241 15.400 -40.122 1.00 63.67 ? 135 LYS B CE 1 ATOM 5011 N NZ . LYS B 1 135 ? -28.223 14.546 -41.351 1.00 63.82 ? 135 LYS B NZ 1 ATOM 5012 N N . TRP B 1 136 ? -25.202 12.408 -37.264 1.00 58.48 ? 136 TRP B N 1 ATOM 5013 C CA . TRP B 1 136 ? -24.103 11.506 -37.582 1.00 57.50 ? 136 TRP B CA 1 ATOM 5014 C C . TRP B 1 136 ? -23.315 12.067 -38.755 1.00 57.48 ? 136 TRP B C 1 ATOM 5015 O O . TRP B 1 136 ? -23.889 12.672 -39.667 1.00 57.51 ? 136 TRP B O 1 ATOM 5016 C CB . TRP B 1 136 ? -24.625 10.117 -37.935 1.00 57.13 ? 136 TRP B CB 1 ATOM 5017 C CG . TRP B 1 136 ? -25.122 9.332 -36.760 1.00 55.62 ? 136 TRP B CG 1 ATOM 5018 C CD1 . TRP B 1 136 ? -26.412 9.240 -36.318 1.00 54.24 ? 136 TRP B CD1 1 ATOM 5019 C CD2 . TRP B 1 136 ? -24.337 8.517 -35.878 1.00 53.88 ? 136 TRP B CD2 1 ATOM 5020 N NE1 . TRP B 1 136 ? -26.478 8.423 -35.217 1.00 53.32 ? 136 TRP B NE1 1 ATOM 5021 C CE2 . TRP B 1 136 ? -25.220 7.962 -34.927 1.00 52.93 ? 136 TRP B CE2 1 ATOM 5022 C CE3 . TRP B 1 136 ? -22.972 8.202 -35.801 1.00 53.06 ? 136 TRP B CE3 1 ATOM 5023 C CZ2 . TRP B 1 136 ? -24.786 7.116 -33.908 1.00 52.04 ? 136 TRP B CZ2 1 ATOM 5024 C CZ3 . TRP B 1 136 ? -22.540 7.356 -34.786 1.00 52.08 ? 136 TRP B CZ3 1 ATOM 5025 C CH2 . TRP B 1 136 ? -23.448 6.822 -33.855 1.00 51.81 ? 136 TRP B CH2 1 ATOM 5026 N N . ILE B 1 137 ? -22.002 11.859 -38.723 1.00 57.33 ? 137 ILE B N 1 ATOM 5027 C CA . ILE B 1 137 ? -21.092 12.416 -39.716 1.00 57.32 ? 137 ILE B CA 1 ATOM 5028 C C . ILE B 1 137 ? -20.075 11.361 -40.158 1.00 57.49 ? 137 ILE B C 1 ATOM 5029 O O . ILE B 1 137 ? -19.349 10.798 -39.333 1.00 57.40 ? 137 ILE B O 1 ATOM 5030 C CB . ILE B 1 137 ? -20.360 13.678 -39.166 1.00 57.34 ? 137 ILE B CB 1 ATOM 5031 C CG1 . ILE B 1 137 ? -21.370 14.726 -38.684 1.00 57.30 ? 137 ILE B CG1 1 ATOM 5032 C CG2 . ILE B 1 137 ? -19.439 14.286 -40.223 1.00 57.19 ? 137 ILE B CG2 1 ATOM 5033 C CD1 . ILE B 1 137 ? -20.883 15.579 -37.536 1.00 57.66 ? 137 ILE B CD1 1 ATOM 5034 N N . LEU B 1 138 ? -20.032 11.102 -41.463 1.00 57.73 ? 138 LEU B N 1 ATOM 5035 C CA . LEU B 1 138 ? -19.099 10.141 -42.048 1.00 58.24 ? 138 LEU B CA 1 ATOM 5036 C C . LEU B 1 138 ? -17.649 10.599 -41.838 1.00 58.66 ? 138 LEU B C 1 ATOM 5037 O O . LEU B 1 138 ? -17.314 11.747 -42.125 1.00 58.82 ? 138 LEU B O 1 ATOM 5038 C CB . LEU B 1 138 ? -19.415 9.953 -43.541 1.00 58.13 ? 138 LEU B CB 1 ATOM 5039 C CG . LEU B 1 138 ? -18.742 8.845 -44.365 1.00 58.20 ? 138 LEU B CG 1 ATOM 5040 C CD1 . LEU B 1 138 ? -19.213 7.456 -43.953 1.00 58.12 ? 138 LEU B CD1 1 ATOM 5041 C CD2 . LEU B 1 138 ? -18.986 9.059 -45.848 1.00 57.86 ? 138 LEU B CD2 1 ATOM 5042 N N . LEU B 1 139 ? -16.801 9.708 -41.321 1.00 59.17 ? 139 LEU B N 1 ATOM 5043 C CA . LEU B 1 139 ? -15.397 10.038 -41.038 1.00 59.75 ? 139 LEU B CA 1 ATOM 5044 C C . LEU B 1 139 ? -14.624 10.530 -42.260 1.00 60.28 ? 139 LEU B C 1 ATOM 5045 O O . LEU B 1 139 ? -13.774 11.407 -42.134 1.00 60.41 ? 139 LEU B O 1 ATOM 5046 C CB . LEU B 1 139 ? -14.647 8.857 -40.396 1.00 59.72 ? 139 LEU B CB 1 ATOM 5047 C CG . LEU B 1 139 ? -14.526 8.671 -38.871 1.00 59.43 ? 139 LEU B CG 1 ATOM 5048 C CD1 . LEU B 1 139 ? -14.020 9.922 -38.154 1.00 59.04 ? 139 LEU B CD1 1 ATOM 5049 C CD2 . LEU B 1 139 ? -15.826 8.199 -38.247 1.00 59.70 ? 139 LEU B CD2 1 ATOM 5050 N N . GLU B 1 140 ? -14.917 9.968 -43.433 1.00 60.95 ? 140 GLU B N 1 ATOM 5051 C CA . GLU B 1 140 ? -14.249 10.382 -44.678 1.00 61.65 ? 140 GLU B CA 1 ATOM 5052 C C . GLU B 1 140 ? -14.540 11.835 -45.070 1.00 61.78 ? 140 GLU B C 1 ATOM 5053 O O . GLU B 1 140 ? -13.705 12.484 -45.699 1.00 61.88 ? 140 GLU B O 1 ATOM 5054 C CB . GLU B 1 140 ? -14.562 9.425 -45.836 1.00 61.79 ? 140 GLU B CB 1 ATOM 5055 C CG . GLU B 1 140 ? -13.777 8.107 -45.764 1.00 62.79 ? 140 GLU B CG 1 ATOM 5056 C CD . GLU B 1 140 ? -13.963 7.214 -46.984 1.00 63.70 ? 140 GLU B CD 1 ATOM 5057 O OE1 . GLU B 1 140 ? -14.352 7.731 -48.055 1.00 63.88 ? 140 GLU B OE1 1 ATOM 5058 O OE2 . GLU B 1 140 ? -13.706 5.991 -46.868 1.00 63.79 ? 140 GLU B OE2 1 ATOM 5059 N N . ASP B 1 141 ? -15.715 12.337 -44.692 1.00 61.94 ? 141 ASP B N 1 ATOM 5060 C CA . ASP B 1 141 ? -16.041 13.752 -44.868 1.00 62.23 ? 141 ASP B CA 1 ATOM 5061 C C . ASP B 1 141 ? -15.309 14.600 -43.833 1.00 62.28 ? 141 ASP B C 1 ATOM 5062 O O . ASP B 1 141 ? -14.729 15.631 -44.171 1.00 62.49 ? 141 ASP B O 1 ATOM 5063 C CB . ASP B 1 141 ? -17.554 13.998 -44.769 1.00 62.22 ? 141 ASP B CB 1 ATOM 5064 C CG . ASP B 1 141 ? -18.327 13.441 -45.958 1.00 62.56 ? 141 ASP B CG 1 ATOM 5065 O OD1 . ASP B 1 141 ? -17.702 12.929 -46.914 1.00 62.66 ? 141 ASP B OD1 1 ATOM 5066 O OD2 . ASP B 1 141 ? -19.575 13.518 -45.934 1.00 62.67 ? 141 ASP B OD2 1 ATOM 5067 N N . TYR B 1 142 ? -15.331 14.147 -42.579 1.00 62.26 ? 142 TYR B N 1 ATOM 5068 C CA . TYR B 1 142 ? -14.750 14.879 -41.448 1.00 62.27 ? 142 TYR B CA 1 ATOM 5069 C C . TYR B 1 142 ? -13.251 15.124 -41.606 1.00 62.03 ? 142 TYR B C 1 ATOM 5070 O O . TYR B 1 142 ? -12.754 16.193 -41.249 1.00 61.92 ? 142 TYR B O 1 ATOM 5071 C CB . TYR B 1 142 ? -15.008 14.126 -40.139 1.00 62.40 ? 142 TYR B CB 1 ATOM 5072 C CG . TYR B 1 142 ? -15.222 15.008 -38.928 1.00 62.87 ? 142 TYR B CG 1 ATOM 5073 C CD1 . TYR B 1 142 ? -16.511 15.322 -38.498 1.00 63.65 ? 142 TYR B CD1 1 ATOM 5074 C CD2 . TYR B 1 142 ? -14.143 15.515 -38.202 1.00 63.32 ? 142 TYR B CD2 1 ATOM 5075 C CE1 . TYR B 1 142 ? -16.728 16.124 -37.379 1.00 64.13 ? 142 TYR B CE1 1 ATOM 5076 C CE2 . TYR B 1 142 ? -14.345 16.322 -37.081 1.00 63.93 ? 142 TYR B CE2 1 ATOM 5077 C CZ . TYR B 1 142 ? -15.643 16.620 -36.676 1.00 64.40 ? 142 TYR B CZ 1 ATOM 5078 O OH . TYR B 1 142 ? -15.862 17.412 -35.570 1.00 64.54 ? 142 TYR B OH 1 ATOM 5079 N N . ARG B 1 143 ? -12.542 14.130 -42.140 1.00 61.86 ? 143 ARG B N 1 ATOM 5080 C CA . ARG B 1 143 ? -11.091 14.211 -42.312 1.00 61.76 ? 143 ARG B CA 1 ATOM 5081 C C . ARG B 1 143 ? -10.692 15.168 -43.431 1.00 61.81 ? 143 ARG B C 1 ATOM 5082 O O . ARG B 1 143 ? -9.587 15.709 -43.427 1.00 61.77 ? 143 ARG B O 1 ATOM 5083 C CB . ARG B 1 143 ? -10.487 12.824 -42.544 1.00 61.68 ? 143 ARG B CB 1 ATOM 5084 C CG . ARG B 1 143 ? -10.407 11.977 -41.292 1.00 61.11 ? 143 ARG B CG 1 ATOM 5085 C CD . ARG B 1 143 ? -9.571 10.740 -41.512 1.00 60.44 ? 143 ARG B CD 1 ATOM 5086 N NE . ARG B 1 143 ? -9.232 10.094 -40.247 1.00 60.28 ? 143 ARG B NE 1 ATOM 5087 C CZ . ARG B 1 143 ? -9.887 9.062 -39.717 1.00 59.79 ? 143 ARG B CZ 1 ATOM 5088 N NH1 . ARG B 1 143 ? -10.933 8.525 -40.338 1.00 59.11 ? 143 ARG B NH1 1 ATOM 5089 N NH2 . ARG B 1 143 ? -9.484 8.555 -38.559 1.00 59.33 ? 143 ARG B NH2 1 ATOM 5090 N N . LYS B 1 144 ? -11.599 15.376 -44.379 1.00 61.94 ? 144 LYS B N 1 ATOM 5091 C CA . LYS B 1 144 ? -11.375 16.321 -45.463 1.00 62.03 ? 144 LYS B CA 1 ATOM 5092 C C . LYS B 1 144 ? -11.481 17.769 -44.999 1.00 62.14 ? 144 LYS B C 1 ATOM 5093 O O . LYS B 1 144 ? -10.734 18.621 -45.470 1.00 62.22 ? 144 LYS B O 1 ATOM 5094 C CB . LYS B 1 144 ? -12.320 16.035 -46.628 1.00 62.00 ? 144 LYS B CB 1 ATOM 5095 C CG . LYS B 1 144 ? -11.843 14.871 -47.477 1.00 62.09 ? 144 LYS B CG 1 ATOM 5096 C CD . LYS B 1 144 ? -12.920 14.336 -48.397 1.00 62.25 ? 144 LYS B CD 1 ATOM 5097 C CE . LYS B 1 144 ? -12.454 13.040 -49.049 1.00 62.14 ? 144 LYS B CE 1 ATOM 5098 N NZ . LYS B 1 144 ? -13.459 12.490 -49.994 1.00 62.02 ? 144 LYS B NZ 1 ATOM 5099 N N . ARG B 1 145 ? -12.382 18.031 -44.053 1.00 62.29 ? 145 ARG B N 1 ATOM 5100 C CA . ARG B 1 145 ? -12.638 19.385 -43.556 1.00 62.41 ? 145 ARG B CA 1 ATOM 5101 C C . ARG B 1 145 ? -11.667 19.888 -42.476 1.00 62.13 ? 145 ARG B C 1 ATOM 5102 O O . ARG B 1 145 ? -11.703 21.067 -42.121 1.00 62.21 ? 145 ARG B O 1 ATOM 5103 C CB . ARG B 1 145 ? -14.076 19.503 -43.036 1.00 62.74 ? 145 ARG B CB 1 ATOM 5104 C CG . ARG B 1 145 ? -15.156 19.503 -44.106 1.00 64.28 ? 145 ARG B CG 1 ATOM 5105 C CD . ARG B 1 145 ? -16.541 19.640 -43.473 1.00 66.84 ? 145 ARG B CD 1 ATOM 5106 N NE . ARG B 1 145 ? -17.521 18.763 -44.118 1.00 69.08 ? 145 ARG B NE 1 ATOM 5107 C CZ . ARG B 1 145 ? -18.588 18.240 -43.513 1.00 70.18 ? 145 ARG B CZ 1 ATOM 5108 N NH1 . ARG B 1 145 ? -18.837 18.498 -42.231 1.00 70.61 ? 145 ARG B NH1 1 ATOM 5109 N NH2 . ARG B 1 145 ? -19.410 17.449 -44.194 1.00 70.32 ? 145 ARG B NH2 1 ATOM 5110 N N . VAL B 1 146 ? -10.813 19.016 -41.948 1.00 61.80 ? 146 VAL B N 1 ATOM 5111 C CA . VAL B 1 146 ? -9.888 19.422 -40.883 1.00 61.59 ? 146 VAL B CA 1 ATOM 5112 C C . VAL B 1 146 ? -8.505 19.794 -41.412 1.00 61.46 ? 146 VAL B C 1 ATOM 5113 O O . VAL B 1 146 ? -8.000 19.175 -42.352 1.00 61.37 ? 146 VAL B O 1 ATOM 5114 C CB . VAL B 1 146 ? -9.765 18.359 -39.748 1.00 61.61 ? 146 VAL B CB 1 ATOM 5115 C CG1 . VAL B 1 146 ? -11.082 18.216 -39.000 1.00 61.64 ? 146 VAL B CG1 1 ATOM 5116 C CG2 . VAL B 1 146 ? -9.288 17.011 -40.287 1.00 61.55 ? 146 VAL B CG2 1 ATOM 5117 N N . GLN B 1 147 ? -7.903 20.814 -40.802 1.00 61.38 ? 147 GLN B N 1 ATOM 5118 C CA . GLN B 1 147 ? -6.566 21.272 -41.183 1.00 61.41 ? 147 GLN B CA 1 ATOM 5119 C C . GLN B 1 147 ? -5.508 20.185 -41.003 1.00 61.07 ? 147 GLN B C 1 ATOM 5120 O O . GLN B 1 147 ? -4.887 19.756 -41.976 1.00 61.16 ? 147 GLN B O 1 ATOM 5121 C CB . GLN B 1 147 ? -6.173 22.543 -40.416 1.00 61.62 ? 147 GLN B CB 1 ATOM 5122 C CG . GLN B 1 147 ? -5.980 23.787 -41.294 1.00 62.23 ? 147 GLN B CG 1 ATOM 5123 C CD . GLN B 1 147 ? -7.268 24.540 -41.581 1.00 63.16 ? 147 GLN B CD 1 ATOM 5124 O OE1 . GLN B 1 147 ? -8.367 24.021 -41.381 1.00 63.68 ? 147 GLN B OE1 1 ATOM 5125 N NE2 . GLN B 1 147 ? -7.135 25.778 -42.057 1.00 62.93 ? 147 GLN B NE2 1 ATOM 5126 N N . ASN B 1 148 ? -5.321 19.739 -39.762 1.00 60.67 ? 148 ASN B N 1 ATOM 5127 C CA . ASN B 1 148 ? -4.338 18.703 -39.442 1.00 60.17 ? 148 ASN B CA 1 ATOM 5128 C C . ASN B 1 148 ? -5.023 17.368 -39.158 1.00 59.79 ? 148 ASN B C 1 ATOM 5129 O O . ASN B 1 148 ? -5.632 17.187 -38.100 1.00 59.73 ? 148 ASN B O 1 ATOM 5130 C CB . ASN B 1 148 ? -3.466 19.134 -38.253 1.00 60.10 ? 148 ASN B CB 1 ATOM 5131 C CG . ASN B 1 148 ? -2.138 18.388 -38.189 1.00 60.09 ? 148 ASN B CG 1 ATOM 5132 O OD1 . ASN B 1 148 ? -1.917 17.404 -38.899 1.00 59.55 ? 148 ASN B OD1 1 ATOM 5133 N ND2 . ASN B 1 148 ? -1.244 18.860 -37.326 1.00 60.39 ? 148 ASN B ND2 1 ATOM 5134 N N . VAL B 1 149 ? -4.920 16.446 -40.116 1.00 59.15 ? 149 VAL B N 1 ATOM 5135 C CA . VAL B 1 149 ? -5.552 15.131 -40.013 1.00 58.47 ? 149 VAL B CA 1 ATOM 5136 C C . VAL B 1 149 ? -4.875 14.256 -38.952 1.00 57.99 ? 149 VAL B C 1 ATOM 5137 O O . VAL B 1 149 ? -5.555 13.574 -38.181 1.00 57.97 ? 149 VAL B O 1 ATOM 5138 C CB . VAL B 1 149 ? -5.646 14.412 -41.402 1.00 58.51 ? 149 VAL B CB 1 ATOM 5139 C CG1 . VAL B 1 149 ? -4.269 14.039 -41.943 1.00 58.75 ? 149 VAL B CG1 1 ATOM 5140 C CG2 . VAL B 1 149 ? -6.547 13.188 -41.328 1.00 58.33 ? 149 VAL B CG2 1 ATOM 5141 N N . THR B 1 150 ? -3.544 14.305 -38.899 1.00 57.32 ? 150 THR B N 1 ATOM 5142 C CA . THR B 1 150 ? -2.771 13.517 -37.933 1.00 56.64 ? 150 THR B CA 1 ATOM 5143 C C . THR B 1 150 ? -3.068 13.917 -36.490 1.00 55.99 ? 150 THR B C 1 ATOM 5144 O O . THR B 1 150 ? -2.984 13.089 -35.592 1.00 55.93 ? 150 THR B O 1 ATOM 5145 C CB . THR B 1 150 ? -1.250 13.598 -38.187 1.00 56.62 ? 150 THR B CB 1 ATOM 5146 O OG1 . THR B 1 150 ? -0.875 14.962 -38.404 1.00 57.13 ? 150 THR B OG1 1 ATOM 5147 C CG2 . THR B 1 150 ? -0.862 12.770 -39.401 1.00 56.41 ? 150 THR B CG2 1 ATOM 5148 N N . GLU B 1 151 ? -3.425 15.183 -36.284 1.00 55.26 ? 151 GLU B N 1 ATOM 5149 C CA . GLU B 1 151 ? -3.807 15.686 -34.962 1.00 54.62 ? 151 GLU B CA 1 ATOM 5150 C C . GLU B 1 151 ? -5.215 15.234 -34.562 1.00 53.73 ? 151 GLU B C 1 ATOM 5151 O O . GLU B 1 151 ? -5.440 14.859 -33.410 1.00 53.75 ? 151 GLU B O 1 ATOM 5152 C CB . GLU B 1 151 ? -3.669 17.220 -34.895 1.00 54.80 ? 151 GLU B CB 1 ATOM 5153 C CG . GLU B 1 151 ? -4.159 17.887 -33.593 1.00 55.97 ? 151 GLU B CG 1 ATOM 5154 C CD . GLU B 1 151 ? -3.541 17.296 -32.311 1.00 57.87 ? 151 GLU B CD 1 ATOM 5155 O OE1 . GLU B 1 151 ? -2.393 16.793 -32.352 1.00 58.29 ? 151 GLU B OE1 1 ATOM 5156 O OE2 . GLU B 1 151 ? -4.211 17.341 -31.253 1.00 58.13 ? 151 GLU B OE2 1 ATOM 5157 N N . PHE B 1 152 ? -6.148 15.270 -35.514 1.00 52.58 ? 152 PHE B N 1 ATOM 5158 C CA . PHE B 1 152 ? -7.505 14.763 -35.311 1.00 51.32 ? 152 PHE B CA 1 ATOM 5159 C C . PHE B 1 152 ? -7.481 13.280 -34.948 1.00 50.48 ? 152 PHE B C 1 ATOM 5160 O O . PHE B 1 152 ? -8.237 12.833 -34.083 1.00 50.31 ? 152 PHE B O 1 ATOM 5161 C CB . PHE B 1 152 ? -8.364 14.999 -36.563 1.00 51.33 ? 152 PHE B CB 1 ATOM 5162 C CG . PHE B 1 152 ? -9.667 14.241 -36.563 1.00 51.14 ? 152 PHE B CG 1 ATOM 5163 C CD1 . PHE B 1 152 ? -10.746 14.683 -35.796 1.00 50.93 ? 152 PHE B CD1 1 ATOM 5164 C CD2 . PHE B 1 152 ? -9.813 13.084 -37.331 1.00 50.76 ? 152 PHE B CD2 1 ATOM 5165 C CE1 . PHE B 1 152 ? -11.951 13.987 -35.789 1.00 50.58 ? 152 PHE B CE1 1 ATOM 5166 C CE2 . PHE B 1 152 ? -11.014 12.378 -37.335 1.00 50.56 ? 152 PHE B CE2 1 ATOM 5167 C CZ . PHE B 1 152 ? -12.088 12.834 -36.563 1.00 50.96 ? 152 PHE B CZ 1 ATOM 5168 N N . ASP B 1 153 ? -6.611 12.530 -35.620 1.00 49.37 ? 153 ASP B N 1 ATOM 5169 C CA . ASP B 1 153 ? -6.450 11.104 -35.359 1.00 48.45 ? 153 ASP B CA 1 ATOM 5170 C C . ASP B 1 153 ? -5.895 10.837 -33.961 1.00 48.15 ? 153 ASP B C 1 ATOM 5171 O O . ASP B 1 153 ? -6.405 9.975 -33.245 1.00 48.06 ? 153 ASP B O 1 ATOM 5172 C CB . ASP B 1 153 ? -5.573 10.453 -36.434 1.00 48.11 ? 153 ASP B CB 1 ATOM 5173 C CG . ASP B 1 153 ? -6.323 10.221 -37.745 1.00 47.24 ? 153 ASP B CG 1 ATOM 5174 O OD1 . ASP B 1 153 ? -7.531 10.537 -37.826 1.00 46.38 ? 153 ASP B OD1 1 ATOM 5175 O OD2 . ASP B 1 153 ? -5.702 9.715 -38.699 1.00 46.06 ? 153 ASP B OD2 1 ATOM 5176 N N . ASP B 1 154 ? -4.866 11.593 -33.576 1.00 47.75 ? 154 ASP B N 1 ATOM 5177 C CA . ASP B 1 154 ? -4.282 11.512 -32.235 1.00 47.29 ? 154 ASP B CA 1 ATOM 5178 C C . ASP B 1 154 ? -5.275 11.848 -31.135 1.00 46.39 ? 154 ASP B C 1 ATOM 5179 O O . ASP B 1 154 ? -5.191 11.293 -30.044 1.00 46.23 ? 154 ASP B O 1 ATOM 5180 C CB . ASP B 1 154 ? -3.056 12.418 -32.112 1.00 47.79 ? 154 ASP B CB 1 ATOM 5181 C CG . ASP B 1 154 ? -1.804 11.795 -32.712 1.00 49.84 ? 154 ASP B CG 1 ATOM 5182 O OD1 . ASP B 1 154 ? -1.699 10.548 -32.726 1.00 52.12 ? 154 ASP B OD1 1 ATOM 5183 O OD2 . ASP B 1 154 ? -0.919 12.556 -33.170 1.00 52.01 ? 154 ASP B OD2 1 ATOM 5184 N N . SER B 1 155 ? -6.211 12.750 -31.427 1.00 45.44 ? 155 SER B N 1 ATOM 5185 C CA . SER B 1 155 ? -7.227 13.140 -30.454 1.00 44.73 ? 155 SER B CA 1 ATOM 5186 C C . SER B 1 155 ? -8.232 12.012 -30.241 1.00 44.13 ? 155 SER B C 1 ATOM 5187 O O . SER B 1 155 ? -8.870 11.927 -29.181 1.00 44.05 ? 155 SER B O 1 ATOM 5188 C CB . SER B 1 155 ? -7.933 14.434 -30.874 1.00 44.64 ? 155 SER B CB 1 ATOM 5189 O OG . SER B 1 155 ? -8.799 14.216 -31.970 1.00 44.94 ? 155 SER B OG 1 ATOM 5190 N N . LEU B 1 156 ? -8.364 11.157 -31.256 1.00 43.38 ? 156 LEU B N 1 ATOM 5191 C CA . LEU B 1 156 ? -9.166 9.942 -31.149 1.00 42.76 ? 156 LEU B CA 1 ATOM 5192 C C . LEU B 1 156 ? -8.444 8.894 -30.305 1.00 42.58 ? 156 LEU B C 1 ATOM 5193 O O . LEU B 1 156 ? -9.066 8.243 -29.474 1.00 42.31 ? 156 LEU B O 1 ATOM 5194 C CB . LEU B 1 156 ? -9.506 9.369 -32.526 1.00 42.53 ? 156 LEU B CB 1 ATOM 5195 C CG . LEU B 1 156 ? -10.463 10.118 -33.456 1.00 41.95 ? 156 LEU B CG 1 ATOM 5196 C CD1 . LEU B 1 156 ? -10.494 9.422 -34.813 1.00 41.00 ? 156 LEU B CD1 1 ATOM 5197 C CD2 . LEU B 1 156 ? -11.856 10.205 -32.875 1.00 40.82 ? 156 LEU B CD2 1 ATOM 5198 N N . LEU B 1 157 ? -7.136 8.747 -30.515 1.00 42.43 ? 157 LEU B N 1 ATOM 5199 C CA . LEU B 1 157 ? -6.310 7.829 -29.729 1.00 42.54 ? 157 LEU B CA 1 ATOM 5200 C C . LEU B 1 157 ? -6.304 8.209 -28.241 1.00 42.62 ? 157 LEU B C 1 ATOM 5201 O O . LEU B 1 157 ? -6.319 7.336 -27.374 1.00 42.54 ? 157 LEU B O 1 ATOM 5202 C CB . LEU B 1 157 ? -4.877 7.804 -30.268 1.00 42.47 ? 157 LEU B CB 1 ATOM 5203 C CG . LEU B 1 157 ? -4.088 6.498 -30.435 1.00 42.89 ? 157 LEU B CG 1 ATOM 5204 C CD1 . LEU B 1 157 ? -2.591 6.804 -30.491 1.00 43.06 ? 157 LEU B CD1 1 ATOM 5205 C CD2 . LEU B 1 157 ? -4.363 5.456 -29.348 1.00 43.32 ? 157 LEU B CD2 1 ATOM 5206 N N . ARG B 1 158 ? -6.297 9.512 -27.960 1.00 42.82 ? 158 ARG B N 1 ATOM 5207 C CA . ARG B 1 158 ? -6.298 10.024 -26.589 1.00 42.98 ? 158 ARG B CA 1 ATOM 5208 C C . ARG B 1 158 ? -7.645 9.847 -25.909 1.00 42.71 ? 158 ARG B C 1 ATOM 5209 O O . ARG B 1 158 ? -7.740 9.899 -24.682 1.00 42.89 ? 158 ARG B O 1 ATOM 5210 C CB . ARG B 1 158 ? -5.888 11.498 -26.547 1.00 43.22 ? 158 ARG B CB 1 ATOM 5211 C CG . ARG B 1 158 ? -4.395 11.734 -26.739 1.00 44.73 ? 158 ARG B CG 1 ATOM 5212 C CD . ARG B 1 158 ? -4.005 13.152 -26.362 1.00 47.88 ? 158 ARG B CD 1 ATOM 5213 N NE . ARG B 1 158 ? -4.816 14.153 -27.055 1.00 50.26 ? 158 ARG B NE 1 ATOM 5214 C CZ . ARG B 1 158 ? -4.524 14.670 -28.245 1.00 51.81 ? 158 ARG B CZ 1 ATOM 5215 N NH1 . ARG B 1 158 ? -3.432 14.283 -28.902 1.00 52.40 ? 158 ARG B NH1 1 ATOM 5216 N NH2 . ARG B 1 158 ? -5.332 15.576 -28.784 1.00 52.28 ? 158 ARG B NH2 1 ATOM 5217 N N . ASN B 1 159 ? -8.684 9.640 -26.706 1.00 42.43 ? 159 ASN B N 1 ATOM 5218 C CA . ASN B 1 159 ? -10.007 9.410 -26.163 1.00 42.32 ? 159 ASN B CA 1 ATOM 5219 C C . ASN B 1 159 ? -10.327 7.916 -25.969 1.00 40.79 ? 159 ASN B C 1 ATOM 5220 O O . ASN B 1 159 ? -11.333 7.559 -25.352 1.00 40.74 ? 159 ASN B O 1 ATOM 5221 C CB . ASN B 1 159 ? -11.077 10.140 -26.994 1.00 43.35 ? 159 ASN B CB 1 ATOM 5222 C CG . ASN B 1 159 ? -12.116 10.789 -26.108 1.00 48.26 ? 159 ASN B CG 1 ATOM 5223 O OD1 . ASN B 1 159 ? -13.236 10.292 -25.975 1.00 50.72 ? 159 ASN B OD1 1 ATOM 5224 N ND2 . ASN B 1 159 ? -11.741 11.892 -25.454 1.00 55.50 ? 159 ASN B ND2 1 ATOM 5225 N N . PHE B 1 160 ? -9.442 7.058 -26.475 1.00 38.89 ? 160 PHE B N 1 ATOM 5226 C CA . PHE B 1 160 ? -9.640 5.611 -26.476 1.00 37.12 ? 160 PHE B CA 1 ATOM 5227 C C . PHE B 1 160 ? -8.858 4.915 -25.357 1.00 36.26 ? 160 PHE B C 1 ATOM 5228 O O . PHE B 1 160 ? -9.001 3.705 -25.154 1.00 36.22 ? 160 PHE B O 1 ATOM 5229 C CB . PHE B 1 160 ? -9.225 5.021 -27.833 1.00 36.85 ? 160 PHE B CB 1 ATOM 5230 C CG . PHE B 1 160 ? -10.218 5.256 -28.955 1.00 35.77 ? 160 PHE B CG 1 ATOM 5231 C CD1 . PHE B 1 160 ? -11.287 6.145 -28.811 1.00 35.05 ? 160 PHE B CD1 1 ATOM 5232 C CD2 . PHE B 1 160 ? -10.061 4.600 -30.176 1.00 34.87 ? 160 PHE B CD2 1 ATOM 5233 C CE1 . PHE B 1 160 ? -12.189 6.357 -29.858 1.00 34.36 ? 160 PHE B CE1 1 ATOM 5234 C CE2 . PHE B 1 160 ? -10.956 4.805 -31.231 1.00 33.96 ? 160 PHE B CE2 1 ATOM 5235 C CZ . PHE B 1 160 ? -12.020 5.689 -31.072 1.00 34.44 ? 160 PHE B CZ 1 ATOM 5236 N N . THR B 1 161 ? -8.008 5.662 -24.655 1.00 34.81 ? 161 THR B N 1 ATOM 5237 C CA . THR B 1 161 ? -7.281 5.106 -23.517 1.00 33.48 ? 161 THR B CA 1 ATOM 5238 C C . THR B 1 161 ? -7.299 6.070 -22.339 1.00 32.69 ? 161 THR B C 1 ATOM 5239 O O . THR B 1 161 ? -7.717 7.233 -22.471 1.00 32.56 ? 161 THR B O 1 ATOM 5240 C CB . THR B 1 161 ? -5.797 4.727 -23.839 1.00 33.53 ? 161 THR B CB 1 ATOM 5241 O OG1 . THR B 1 161 ? -4.969 5.893 -23.778 1.00 34.11 ? 161 THR B OG1 1 ATOM 5242 C CG2 . THR B 1 161 ? -5.649 4.061 -25.201 1.00 33.24 ? 161 THR B CG2 1 ATOM 5243 N N . LEU B 1 162 ? -6.844 5.569 -21.190 1.00 31.34 ? 162 LEU B N 1 ATOM 5244 C CA . LEU B 1 162 ? -6.752 6.357 -19.973 1.00 29.84 ? 162 LEU B CA 1 ATOM 5245 C C . LEU B 1 162 ? -5.413 7.066 -19.887 1.00 29.63 ? 162 LEU B C 1 ATOM 5246 O O . LEU B 1 162 ? -5.256 7.992 -19.085 1.00 29.10 ? 162 LEU B O 1 ATOM 5247 C CB . LEU B 1 162 ? -6.948 5.462 -18.753 1.00 29.32 ? 162 LEU B CB 1 ATOM 5248 C CG . LEU B 1 162 ? -8.364 4.944 -18.498 1.00 27.89 ? 162 LEU B CG 1 ATOM 5249 C CD1 . LEU B 1 162 ? -8.335 3.870 -17.420 1.00 26.11 ? 162 LEU B CD1 1 ATOM 5250 C CD2 . LEU B 1 162 ? -9.320 6.065 -18.123 1.00 24.86 ? 162 LEU B CD2 1 ATOM 5251 N N . VAL B 1 163 ? -4.457 6.615 -20.706 1.00 29.57 ? 163 VAL B N 1 ATOM 5252 C CA . VAL B 1 163 ? -3.090 7.150 -20.722 1.00 29.69 ? 163 VAL B CA 1 ATOM 5253 C C . VAL B 1 163 ? -3.105 8.667 -20.821 1.00 30.47 ? 163 VAL B C 1 ATOM 5254 O O . VAL B 1 163 ? -3.798 9.234 -21.656 1.00 30.61 ? 163 VAL B O 1 ATOM 5255 C CB . VAL B 1 163 ? -2.227 6.540 -21.862 1.00 29.54 ? 163 VAL B CB 1 ATOM 5256 C CG1 . VAL B 1 163 ? -0.787 7.099 -21.844 1.00 28.03 ? 163 VAL B CG1 1 ATOM 5257 C CG2 . VAL B 1 163 ? -2.195 5.034 -21.751 1.00 28.51 ? 163 VAL B CG2 1 ATOM 5258 N N . THR B 1 164 ? -2.356 9.306 -19.932 1.00 31.46 ? 164 THR B N 1 ATOM 5259 C CA . THR B 1 164 ? -2.272 10.753 -19.855 1.00 32.55 ? 164 THR B CA 1 ATOM 5260 C C . THR B 1 164 ? -1.056 11.138 -19.029 1.00 33.49 ? 164 THR B C 1 ATOM 5261 O O . THR B 1 164 ? -0.560 10.351 -18.226 1.00 33.60 ? 164 THR B O 1 ATOM 5262 C CB . THR B 1 164 ? -3.556 11.392 -19.233 1.00 32.31 ? 164 THR B CB 1 ATOM 5263 O OG1 . THR B 1 164 ? -3.383 12.807 -19.129 1.00 32.96 ? 164 THR B OG1 1 ATOM 5264 C CG2 . THR B 1 164 ? -3.853 10.847 -17.846 1.00 32.01 ? 164 THR B CG2 1 ATOM 5265 N N . GLN B 1 165 ? -0.565 12.348 -19.248 1.00 34.78 ? 165 GLN B N 1 ATOM 5266 C CA . GLN B 1 165 ? 0.368 12.948 -18.319 1.00 36.07 ? 165 GLN B CA 1 ATOM 5267 C C . GLN B 1 165 ? -0.442 13.364 -17.109 1.00 36.26 ? 165 GLN B C 1 ATOM 5268 O O . GLN B 1 165 ? -1.647 13.607 -17.215 1.00 36.31 ? 165 GLN B O 1 ATOM 5269 C CB . GLN B 1 165 ? 1.026 14.171 -18.939 1.00 36.50 ? 165 GLN B CB 1 ATOM 5270 C CG . GLN B 1 165 ? 2.101 13.860 -19.958 1.00 39.31 ? 165 GLN B CG 1 ATOM 5271 C CD . GLN B 1 165 ? 2.863 15.107 -20.370 1.00 43.69 ? 165 GLN B CD 1 ATOM 5272 O OE1 . GLN B 1 165 ? 2.536 15.738 -21.378 1.00 45.86 ? 165 GLN B OE1 1 ATOM 5273 N NE2 . GLN B 1 165 ? 3.866 15.488 -19.574 1.00 44.59 ? 165 GLN B NE2 1 ATOM 5274 N N . HIS B 1 166 ? 0.218 13.438 -15.960 1.00 36.66 ? 166 HIS B N 1 ATOM 5275 C CA . HIS B 1 166 ? -0.419 13.893 -14.719 1.00 36.98 ? 166 HIS B CA 1 ATOM 5276 C C . HIS B 1 166 ? -1.759 13.218 -14.410 1.00 36.52 ? 166 HIS B C 1 ATOM 5277 O O . HIS B 1 166 ? -2.774 13.897 -14.227 1.00 36.80 ? 166 HIS B O 1 ATOM 5278 C CB . HIS B 1 166 ? -0.548 15.422 -14.721 1.00 37.31 ? 166 HIS B CB 1 ATOM 5279 C CG . HIS B 1 166 ? 0.756 16.116 -14.944 1.00 39.23 ? 166 HIS B CG 1 ATOM 5280 N ND1 . HIS B 1 166 ? 1.023 16.850 -16.080 1.00 40.73 ? 166 HIS B ND1 1 ATOM 5281 C CD2 . HIS B 1 166 ? 1.887 16.143 -14.199 1.00 40.44 ? 166 HIS B CD2 1 ATOM 5282 C CE1 . HIS B 1 166 ? 2.256 17.322 -16.011 1.00 42.45 ? 166 HIS B CE1 1 ATOM 5283 N NE2 . HIS B 1 166 ? 2.802 16.908 -14.880 1.00 42.03 ? 166 HIS B NE2 1 ATOM 5284 N N . PRO B 1 167 ? -1.764 11.873 -14.338 1.00 36.12 ? 167 PRO B N 1 ATOM 5285 C CA . PRO B 1 167 ? -2.996 11.164 -13.993 1.00 35.92 ? 167 PRO B CA 1 ATOM 5286 C C . PRO B 1 167 ? -3.482 11.486 -12.581 1.00 35.96 ? 167 PRO B C 1 ATOM 5287 O O . PRO B 1 167 ? -4.664 11.317 -12.294 1.00 35.96 ? 167 PRO B O 1 ATOM 5288 C CB . PRO B 1 167 ? -2.598 9.691 -14.105 1.00 35.89 ? 167 PRO B CB 1 ATOM 5289 C CG . PRO B 1 167 ? -1.119 9.685 -13.942 1.00 35.77 ? 167 PRO B CG 1 ATOM 5290 C CD . PRO B 1 167 ? -0.640 10.945 -14.556 1.00 35.71 ? 167 PRO B CD 1 ATOM 5291 N N . GLU B 1 168 ? -2.574 11.951 -11.722 1.00 36.24 ? 168 GLU B N 1 ATOM 5292 C CA . GLU B 1 168 ? -2.906 12.375 -10.354 1.00 36.62 ? 168 GLU B CA 1 ATOM 5293 C C . GLU B 1 168 ? -3.817 13.604 -10.337 1.00 36.46 ? 168 GLU B C 1 ATOM 5294 O O . GLU B 1 168 ? -4.607 13.774 -9.414 1.00 36.63 ? 168 GLU B O 1 ATOM 5295 C CB . GLU B 1 168 ? -1.630 12.629 -9.525 1.00 37.00 ? 168 GLU B CB 1 ATOM 5296 C CG . GLU B 1 168 ? -0.848 13.932 -9.840 1.00 38.48 ? 168 GLU B CG 1 ATOM 5297 C CD . GLU B 1 168 ? -0.036 13.876 -11.144 1.00 41.55 ? 168 GLU B CD 1 ATOM 5298 O OE1 . GLU B 1 168 ? 0.517 14.923 -11.566 1.00 42.10 ? 168 GLU B OE1 1 ATOM 5299 O OE2 . GLU B 1 168 ? 0.056 12.784 -11.751 1.00 43.06 ? 168 GLU B OE2 1 ATOM 5300 N N . VAL B 1 169 ? -3.697 14.445 -11.365 1.00 36.27 ? 169 VAL B N 1 ATOM 5301 C CA . VAL B 1 169 ? -4.517 15.647 -11.516 1.00 36.06 ? 169 VAL B CA 1 ATOM 5302 C C . VAL B 1 169 ? -5.805 15.358 -12.298 1.00 35.77 ? 169 VAL B C 1 ATOM 5303 O O . VAL B 1 169 ? -6.882 15.837 -11.929 1.00 35.76 ? 169 VAL B O 1 ATOM 5304 C CB . VAL B 1 169 ? -3.729 16.798 -12.201 1.00 36.17 ? 169 VAL B CB 1 ATOM 5305 C CG1 . VAL B 1 169 ? -4.606 18.028 -12.375 1.00 36.01 ? 169 VAL B CG1 1 ATOM 5306 C CG2 . VAL B 1 169 ? -2.492 17.145 -11.392 1.00 36.31 ? 169 VAL B CG2 1 ATOM 5307 N N . ILE B 1 170 ? -5.690 14.573 -13.368 1.00 35.28 ? 170 ILE B N 1 ATOM 5308 C CA . ILE B 1 170 ? -6.846 14.240 -14.205 1.00 34.84 ? 170 ILE B CA 1 ATOM 5309 C C . ILE B 1 170 ? -7.864 13.385 -13.434 1.00 34.30 ? 170 ILE B C 1 ATOM 5310 O O . ILE B 1 170 ? -9.062 13.691 -13.422 1.00 34.14 ? 170 ILE B O 1 ATOM 5311 C CB . ILE B 1 170 ? -6.425 13.549 -15.546 1.00 35.08 ? 170 ILE B CB 1 ATOM 5312 C CG1 . ILE B 1 170 ? -5.314 14.337 -16.273 1.00 35.62 ? 170 ILE B CG1 1 ATOM 5313 C CG2 . ILE B 1 170 ? -7.625 13.327 -16.459 1.00 34.97 ? 170 ILE B CG2 1 ATOM 5314 C CD1 . ILE B 1 170 ? -5.618 15.826 -16.566 1.00 37.14 ? 170 ILE B CD1 1 ATOM 5315 N N . TYR B 1 171 ? -7.379 12.329 -12.780 1.00 33.40 ? 171 TYR B N 1 ATOM 5316 C CA . TYR B 1 171 ? -8.244 11.394 -12.062 1.00 32.45 ? 171 TYR B CA 1 ATOM 5317 C C . TYR B 1 171 ? -8.108 11.618 -10.565 1.00 32.50 ? 171 TYR B C 1 ATOM 5318 O O . TYR B 1 171 ? -7.301 10.972 -9.898 1.00 32.71 ? 171 TYR B O 1 ATOM 5319 C CB . TYR B 1 171 ? -7.905 9.947 -12.436 1.00 32.12 ? 171 TYR B CB 1 ATOM 5320 C CG . TYR B 1 171 ? -7.783 9.704 -13.928 1.00 30.68 ? 171 TYR B CG 1 ATOM 5321 C CD1 . TYR B 1 171 ? -8.854 9.967 -14.787 1.00 30.02 ? 171 TYR B CD1 1 ATOM 5322 C CD2 . TYR B 1 171 ? -6.602 9.215 -14.478 1.00 29.03 ? 171 TYR B CD2 1 ATOM 5323 C CE1 . TYR B 1 171 ? -8.751 9.756 -16.161 1.00 29.04 ? 171 TYR B CE1 1 ATOM 5324 C CE2 . TYR B 1 171 ? -6.486 8.991 -15.853 1.00 29.02 ? 171 TYR B CE2 1 ATOM 5325 C CZ . TYR B 1 171 ? -7.568 9.269 -16.689 1.00 28.69 ? 171 TYR B CZ 1 ATOM 5326 O OH . TYR B 1 171 ? -7.470 9.059 -18.042 1.00 27.64 ? 171 TYR B OH 1 ATOM 5327 N N . THR B 1 172 ? -8.896 12.552 -10.044 1.00 32.26 ? 172 THR B N 1 ATOM 5328 C CA . THR B 1 172 ? -8.764 12.996 -8.658 1.00 31.89 ? 172 THR B CA 1 ATOM 5329 C C . THR B 1 172 ? -9.133 11.922 -7.643 1.00 31.08 ? 172 THR B C 1 ATOM 5330 O O . THR B 1 172 ? -8.547 11.869 -6.562 1.00 31.13 ? 172 THR B O 1 ATOM 5331 C CB . THR B 1 172 ? -9.592 14.252 -8.392 1.00 32.15 ? 172 THR B CB 1 ATOM 5332 O OG1 . THR B 1 172 ? -10.890 14.094 -8.986 1.00 33.39 ? 172 THR B OG1 1 ATOM 5333 C CG2 . THR B 1 172 ? -8.898 15.468 -8.995 1.00 32.58 ? 172 THR B CG2 1 ATOM 5334 N N . ASN B 1 173 ? -10.094 11.071 -8.003 1.00 29.90 ? 173 ASN B N 1 ATOM 5335 C CA . ASN B 1 173 ? -10.525 9.963 -7.162 1.00 28.68 ? 173 ASN B CA 1 ATOM 5336 C C . ASN B 1 173 ? -10.901 8.712 -7.968 1.00 28.15 ? 173 ASN B C 1 ATOM 5337 O O . ASN B 1 173 ? -10.810 8.695 -9.198 1.00 27.94 ? 173 ASN B O 1 ATOM 5338 C CB . ASN B 1 173 ? -11.681 10.393 -6.265 1.00 28.59 ? 173 ASN B CB 1 ATOM 5339 C CG . ASN B 1 173 ? -12.888 10.837 -7.048 1.00 28.80 ? 173 ASN B CG 1 ATOM 5340 O OD1 . ASN B 1 173 ? -13.464 10.067 -7.821 1.00 29.00 ? 173 ASN B OD1 1 ATOM 5341 N ND2 . ASN B 1 173 ? -13.282 12.090 -6.858 1.00 28.64 ? 173 ASN B ND2 1 ATOM 5342 N N . GLN B 1 174 ? -11.330 7.671 -7.264 1.00 27.30 ? 174 GLN B N 1 ATOM 5343 C CA . GLN B 1 174 ? -11.649 6.397 -7.886 1.00 26.83 ? 174 GLN B CA 1 ATOM 5344 C C . GLN B 1 174 ? -12.941 6.433 -8.708 1.00 26.83 ? 174 GLN B C 1 ATOM 5345 O O . GLN B 1 174 ? -13.094 5.675 -9.670 1.00 26.73 ? 174 GLN B O 1 ATOM 5346 C CB . GLN B 1 174 ? -11.670 5.278 -6.834 1.00 26.62 ? 174 GLN B CB 1 ATOM 5347 C CG . GLN B 1 174 ? -10.260 4.803 -6.473 1.00 26.06 ? 174 GLN B CG 1 ATOM 5348 C CD . GLN B 1 174 ? -10.189 3.828 -5.309 1.00 25.46 ? 174 GLN B CD 1 ATOM 5349 O OE1 . GLN B 1 174 ? -9.172 3.756 -4.629 1.00 26.66 ? 174 GLN B OE1 1 ATOM 5350 N NE2 . GLN B 1 174 ? -11.249 3.068 -5.083 1.00 24.52 ? 174 GLN B NE2 1 ATOM 5351 N N . ASN B 1 175 ? -13.868 7.310 -8.332 1.00 26.70 ? 175 ASN B N 1 ATOM 5352 C CA . ASN B 1 175 ? -15.102 7.472 -9.098 1.00 26.51 ? 175 ASN B CA 1 ATOM 5353 C C . ASN B 1 175 ? -14.852 8.148 -10.442 1.00 26.36 ? 175 ASN B C 1 ATOM 5354 O O . ASN B 1 175 ? -15.383 7.716 -11.463 1.00 26.31 ? 175 ASN B O 1 ATOM 5355 C CB . ASN B 1 175 ? -16.175 8.200 -8.280 1.00 26.47 ? 175 ASN B CB 1 ATOM 5356 C CG . ASN B 1 175 ? -16.872 7.280 -7.276 1.00 26.28 ? 175 ASN B CG 1 ATOM 5357 O OD1 . ASN B 1 175 ? -16.632 6.075 -7.239 1.00 26.71 ? 175 ASN B OD1 1 ATOM 5358 N ND2 . ASN B 1 175 ? -17.747 7.852 -6.468 1.00 26.86 ? 175 ASN B ND2 1 ATOM 5359 N N . VAL B 1 176 ? -14.008 9.177 -10.442 1.00 26.23 ? 176 VAL B N 1 ATOM 5360 C CA . VAL B 1 176 ? -13.651 9.863 -11.675 1.00 25.92 ? 176 VAL B CA 1 ATOM 5361 C C . VAL B 1 176 ? -12.961 8.897 -12.659 1.00 26.15 ? 176 VAL B C 1 ATOM 5362 O O . VAL B 1 176 ? -13.336 8.831 -13.839 1.00 26.32 ? 176 VAL B O 1 ATOM 5363 C CB . VAL B 1 176 ? -12.795 11.127 -11.400 1.00 26.08 ? 176 VAL B CB 1 ATOM 5364 C CG1 . VAL B 1 176 ? -12.335 11.790 -12.713 1.00 25.17 ? 176 VAL B CG1 1 ATOM 5365 C CG2 . VAL B 1 176 ? -13.580 12.118 -10.539 1.00 25.27 ? 176 VAL B CG2 1 ATOM 5366 N N . VAL B 1 177 ? -11.986 8.128 -12.180 1.00 25.86 ? 177 VAL B N 1 ATOM 5367 C CA . VAL B 1 177 ? -11.292 7.184 -13.057 1.00 25.70 ? 177 VAL B CA 1 ATOM 5368 C C . VAL B 1 177 ? -12.230 6.097 -13.608 1.00 26.35 ? 177 VAL B C 1 ATOM 5369 O O . VAL B 1 177 ? -12.115 5.710 -14.775 1.00 26.23 ? 177 VAL B O 1 ATOM 5370 C CB . VAL B 1 177 ? -9.989 6.604 -12.426 1.00 25.45 ? 177 VAL B CB 1 ATOM 5371 C CG1 . VAL B 1 177 ? -10.287 5.523 -11.378 1.00 24.55 ? 177 VAL B CG1 1 ATOM 5372 C CG2 . VAL B 1 177 ? -9.060 6.078 -13.517 1.00 24.29 ? 177 VAL B CG2 1 ATOM 5373 N N . TRP B 1 178 ? -13.163 5.622 -12.783 1.00 27.10 ? 178 TRP B N 1 ATOM 5374 C CA . TRP B 1 178 ? -14.122 4.607 -13.230 1.00 28.06 ? 178 TRP B CA 1 ATOM 5375 C C . TRP B 1 178 ? -15.124 5.187 -14.219 1.00 28.56 ? 178 TRP B C 1 ATOM 5376 O O . TRP B 1 178 ? -15.568 4.504 -15.139 1.00 28.39 ? 178 TRP B O 1 ATOM 5377 C CB . TRP B 1 178 ? -14.831 3.931 -12.048 1.00 27.93 ? 178 TRP B CB 1 ATOM 5378 C CG . TRP B 1 178 ? -14.248 2.603 -11.719 1.00 28.19 ? 178 TRP B CG 1 ATOM 5379 C CD1 . TRP B 1 178 ? -13.291 2.333 -10.781 1.00 28.30 ? 178 TRP B CD1 1 ATOM 5380 C CD2 . TRP B 1 178 ? -14.563 1.350 -12.342 1.00 28.77 ? 178 TRP B CD2 1 ATOM 5381 N NE1 . TRP B 1 178 ? -12.998 0.987 -10.775 1.00 27.98 ? 178 TRP B NE1 1 ATOM 5382 C CE2 . TRP B 1 178 ? -13.763 0.361 -11.724 1.00 28.46 ? 178 TRP B CE2 1 ATOM 5383 C CE3 . TRP B 1 178 ? -15.448 0.965 -13.356 1.00 28.43 ? 178 TRP B CE3 1 ATOM 5384 C CZ2 . TRP B 1 178 ? -13.818 -0.988 -12.094 1.00 29.02 ? 178 TRP B CZ2 1 ATOM 5385 C CZ3 . TRP B 1 178 ? -15.506 -0.376 -13.723 1.00 28.39 ? 178 TRP B CZ3 1 ATOM 5386 C CH2 . TRP B 1 178 ? -14.691 -1.336 -13.094 1.00 29.01 ? 178 TRP B CH2 1 ATOM 5387 N N . SER B 1 179 ? -15.457 6.458 -14.025 1.00 29.69 ? 179 SER B N 1 ATOM 5388 C CA . SER B 1 179 ? -16.323 7.188 -14.940 1.00 30.62 ? 179 SER B CA 1 ATOM 5389 C C . SER B 1 179 ? -15.703 7.256 -16.342 1.00 31.15 ? 179 SER B C 1 ATOM 5390 O O . SER B 1 179 ? -16.361 6.916 -17.332 1.00 31.40 ? 179 SER B O 1 ATOM 5391 C CB . SER B 1 179 ? -16.594 8.582 -14.396 1.00 30.50 ? 179 SER B CB 1 ATOM 5392 O OG . SER B 1 179 ? -17.474 9.272 -15.251 1.00 32.17 ? 179 SER B OG 1 ATOM 5393 N N . LYS B 1 180 ? -14.434 7.663 -16.414 1.00 31.56 ? 180 LYS B N 1 ATOM 5394 C CA . LYS B 1 180 ? -13.699 7.722 -17.686 1.00 31.96 ? 180 LYS B CA 1 ATOM 5395 C C . LYS B 1 180 ? -13.502 6.336 -18.297 1.00 31.84 ? 180 LYS B C 1 ATOM 5396 O O . LYS B 1 180 ? -13.685 6.156 -19.506 1.00 31.78 ? 180 LYS B O 1 ATOM 5397 C CB . LYS B 1 180 ? -12.348 8.416 -17.506 1.00 32.15 ? 180 LYS B CB 1 ATOM 5398 C CG . LYS B 1 180 ? -12.429 9.832 -16.942 1.00 34.26 ? 180 LYS B CG 1 ATOM 5399 C CD . LYS B 1 180 ? -13.123 10.805 -17.902 1.00 37.17 ? 180 LYS B CD 1 ATOM 5400 C CE . LYS B 1 180 ? -13.201 12.221 -17.308 1.00 38.43 ? 180 LYS B CE 1 ATOM 5401 N NZ . LYS B 1 180 ? -14.076 13.140 -18.109 1.00 38.47 ? 180 LYS B NZ 1 ATOM 5402 N N . PHE B 1 181 ? -13.140 5.369 -17.449 1.00 31.79 ? 181 PHE B N 1 ATOM 5403 C CA . PHE B 1 181 ? -12.963 3.957 -17.834 1.00 31.80 ? 181 PHE B CA 1 ATOM 5404 C C . PHE B 1 181 ? -14.163 3.433 -18.619 1.00 31.83 ? 181 PHE B C 1 ATOM 5405 O O . PHE B 1 181 ? -14.034 3.045 -19.780 1.00 31.54 ? 181 PHE B O 1 ATOM 5406 C CB . PHE B 1 181 ? -12.730 3.092 -16.576 1.00 31.83 ? 181 PHE B CB 1 ATOM 5407 C CG . PHE B 1 181 ? -12.155 1.714 -16.852 1.00 31.29 ? 181 PHE B CG 1 ATOM 5408 C CD1 . PHE B 1 181 ? -11.087 1.541 -17.733 1.00 30.24 ? 181 PHE B CD1 1 ATOM 5409 C CD2 . PHE B 1 181 ? -12.653 0.594 -16.188 1.00 31.19 ? 181 PHE B CD2 1 ATOM 5410 C CE1 . PHE B 1 181 ? -10.543 0.274 -17.971 1.00 29.63 ? 181 PHE B CE1 1 ATOM 5411 C CE2 . PHE B 1 181 ? -12.111 -0.685 -16.420 1.00 30.03 ? 181 PHE B CE2 1 ATOM 5412 C CZ . PHE B 1 181 ? -11.051 -0.839 -17.316 1.00 29.55 ? 181 PHE B CZ 1 ATOM 5413 N N . GLU B 1 182 ? -15.329 3.464 -17.981 1.00 32.13 ? 182 GLU B N 1 ATOM 5414 C CA . GLU B 1 182 ? -16.572 2.993 -18.579 1.00 32.53 ? 182 GLU B CA 1 ATOM 5415 C C . GLU B 1 182 ? -16.953 3.780 -19.841 1.00 31.83 ? 182 GLU B C 1 ATOM 5416 O O . GLU B 1 182 ? -17.448 3.197 -20.808 1.00 31.77 ? 182 GLU B O 1 ATOM 5417 C CB . GLU B 1 182 ? -17.706 3.032 -17.546 1.00 32.81 ? 182 GLU B CB 1 ATOM 5418 C CG . GLU B 1 182 ? -18.526 1.742 -17.486 1.00 36.14 ? 182 GLU B CG 1 ATOM 5419 C CD . GLU B 1 182 ? -17.918 0.684 -16.578 1.00 38.76 ? 182 GLU B CD 1 ATOM 5420 O OE1 . GLU B 1 182 ? -18.410 -0.462 -16.543 1.00 38.96 ? 182 GLU B OE1 1 ATOM 5421 O OE2 . GLU B 1 182 ? -16.943 1.004 -15.884 1.00 41.92 ? 182 GLU B OE2 1 ATOM 5422 N N . THR B 1 183 ? -16.709 5.091 -19.830 1.00 31.19 ? 183 THR B N 1 ATOM 5423 C CA . THR B 1 183 ? -16.972 5.944 -20.996 1.00 30.77 ? 183 THR B CA 1 ATOM 5424 C C . THR B 1 183 ? -16.172 5.489 -22.222 1.00 30.72 ? 183 THR B C 1 ATOM 5425 O O . THR B 1 183 ? -16.688 5.522 -23.346 1.00 30.83 ? 183 THR B O 1 ATOM 5426 C CB . THR B 1 183 ? -16.706 7.449 -20.699 1.00 30.85 ? 183 THR B CB 1 ATOM 5427 O OG1 . THR B 1 183 ? -17.598 7.903 -19.671 1.00 30.37 ? 183 THR B OG1 1 ATOM 5428 C CG2 . THR B 1 183 ? -16.915 8.309 -21.949 1.00 29.84 ? 183 THR B CG2 1 ATOM 5429 N N . ILE B 1 184 ? -14.931 5.056 -22.006 1.00 30.48 ? 184 ILE B N 1 ATOM 5430 C CA . ILE B 1 184 ? -14.120 4.487 -23.090 1.00 30.38 ? 184 ILE B CA 1 ATOM 5431 C C . ILE B 1 184 ? -14.774 3.247 -23.702 1.00 30.84 ? 184 ILE B C 1 ATOM 5432 O O . ILE B 1 184 ? -14.914 3.162 -24.926 1.00 30.68 ? 184 ILE B O 1 ATOM 5433 C CB . ILE B 1 184 ? -12.664 4.194 -22.649 1.00 30.31 ? 184 ILE B CB 1 ATOM 5434 C CG1 . ILE B 1 184 ? -11.953 5.513 -22.321 1.00 29.34 ? 184 ILE B CG1 1 ATOM 5435 C CG2 . ILE B 1 184 ? -11.905 3.391 -23.735 1.00 29.17 ? 184 ILE B CG2 1 ATOM 5436 C CD1 . ILE B 1 184 ? -10.645 5.358 -21.600 1.00 29.47 ? 184 ILE B CD1 1 ATOM 5437 N N . PHE B 1 185 ? -15.187 2.306 -22.853 1.00 31.36 ? 185 PHE B N 1 ATOM 5438 C CA . PHE B 1 185 ? -15.907 1.115 -23.307 1.00 32.12 ? 185 PHE B CA 1 ATOM 5439 C C . PHE B 1 185 ? -17.120 1.502 -24.158 1.00 32.61 ? 185 PHE B C 1 ATOM 5440 O O . PHE B 1 185 ? -17.327 0.940 -25.238 1.00 32.64 ? 185 PHE B O 1 ATOM 5441 C CB . PHE B 1 185 ? -16.328 0.215 -22.131 1.00 31.99 ? 185 PHE B CB 1 ATOM 5442 C CG . PHE B 1 185 ? -15.180 -0.481 -21.452 1.00 32.03 ? 185 PHE B CG 1 ATOM 5443 C CD1 . PHE B 1 185 ? -14.611 -1.625 -22.007 1.00 32.90 ? 185 PHE B CD1 1 ATOM 5444 C CD2 . PHE B 1 185 ? -14.670 -0.003 -20.251 1.00 31.58 ? 185 PHE B CD2 1 ATOM 5445 C CE1 . PHE B 1 185 ? -13.541 -2.285 -21.380 1.00 32.28 ? 185 PHE B CE1 1 ATOM 5446 C CE2 . PHE B 1 185 ? -13.601 -0.643 -19.624 1.00 31.66 ? 185 PHE B CE2 1 ATOM 5447 C CZ . PHE B 1 185 ? -13.036 -1.793 -20.194 1.00 31.74 ? 185 PHE B CZ 1 ATOM 5448 N N . PHE B 1 186 ? -17.900 2.471 -23.680 1.00 33.26 ? 186 PHE B N 1 ATOM 5449 C CA . PHE B 1 186 ? -19.068 2.966 -24.413 1.00 33.85 ? 186 PHE B CA 1 ATOM 5450 C C . PHE B 1 186 ? -18.680 3.510 -25.795 1.00 33.82 ? 186 PHE B C 1 ATOM 5451 O O . PHE B 1 186 ? -19.324 3.184 -26.793 1.00 33.90 ? 186 PHE B O 1 ATOM 5452 C CB . PHE B 1 186 ? -19.812 4.036 -23.598 1.00 34.18 ? 186 PHE B CB 1 ATOM 5453 C CG . PHE B 1 186 ? -20.865 4.782 -24.385 1.00 35.53 ? 186 PHE B CG 1 ATOM 5454 C CD1 . PHE B 1 186 ? -20.532 5.921 -25.117 1.00 36.95 ? 186 PHE B CD1 1 ATOM 5455 C CD2 . PHE B 1 186 ? -22.187 4.343 -24.394 1.00 36.85 ? 186 PHE B CD2 1 ATOM 5456 C CE1 . PHE B 1 186 ? -21.499 6.608 -25.852 1.00 38.55 ? 186 PHE B CE1 1 ATOM 5457 C CE2 . PHE B 1 186 ? -23.167 5.023 -25.124 1.00 37.87 ? 186 PHE B CE2 1 ATOM 5458 C CZ . PHE B 1 186 ? -22.825 6.157 -25.854 1.00 38.50 ? 186 PHE B CZ 1 ATOM 5459 N N . THR B 1 187 ? -17.626 4.328 -25.835 1.00 33.83 ? 187 THR B N 1 ATOM 5460 C CA . THR B 1 187 ? -17.179 4.990 -27.064 1.00 33.82 ? 187 THR B CA 1 ATOM 5461 C C . THR B 1 187 ? -16.734 3.994 -28.140 1.00 33.79 ? 187 THR B C 1 ATOM 5462 O O . THR B 1 187 ? -17.231 4.027 -29.267 1.00 34.12 ? 187 THR B O 1 ATOM 5463 C CB . THR B 1 187 ? -16.040 5.995 -26.782 1.00 33.84 ? 187 THR B CB 1 ATOM 5464 O OG1 . THR B 1 187 ? -16.523 7.044 -25.937 1.00 33.86 ? 187 THR B OG1 1 ATOM 5465 C CG2 . THR B 1 187 ? -15.520 6.611 -28.071 1.00 33.79 ? 187 THR B CG2 1 ATOM 5466 N N . ILE B 1 188 ? -15.814 3.104 -27.780 1.00 33.55 ? 188 ILE B N 1 ATOM 5467 C CA . ILE B 1 188 ? -15.226 2.159 -28.736 1.00 33.07 ? 188 ILE B CA 1 ATOM 5468 C C . ILE B 1 188 ? -16.167 1.016 -29.098 1.00 32.91 ? 188 ILE B C 1 ATOM 5469 O O . ILE B 1 188 ? -15.877 0.230 -30.007 1.00 32.92 ? 188 ILE B O 1 ATOM 5470 C CB . ILE B 1 188 ? -13.890 1.563 -28.219 1.00 32.94 ? 188 ILE B CB 1 ATOM 5471 C CG1 . ILE B 1 188 ? -14.129 0.733 -26.950 1.00 33.02 ? 188 ILE B CG1 1 ATOM 5472 C CG2 . ILE B 1 188 ? -12.854 2.666 -28.019 1.00 32.45 ? 188 ILE B CG2 1 ATOM 5473 C CD1 . ILE B 1 188 ? -12.976 -0.169 -26.554 1.00 33.26 ? 188 ILE B CD1 1 ATOM 5474 N N . SER B 1 189 ? -17.285 0.929 -28.382 1.00 32.67 ? 189 SER B N 1 ATOM 5475 C CA . SER B 1 189 ? -18.229 -0.175 -28.535 1.00 32.55 ? 189 SER B CA 1 ATOM 5476 C C . SER B 1 189 ? -18.784 -0.288 -29.960 1.00 32.17 ? 189 SER B C 1 ATOM 5477 O O . SER B 1 189 ? -18.758 -1.365 -30.545 1.00 32.04 ? 189 SER B O 1 ATOM 5478 C CB . SER B 1 189 ? -19.372 -0.043 -27.522 1.00 32.68 ? 189 SER B CB 1 ATOM 5479 O OG . SER B 1 189 ? -20.023 -1.287 -27.321 1.00 33.53 ? 189 SER B OG 1 ATOM 5480 N N . GLY B 1 190 ? -19.264 0.829 -30.510 1.00 31.94 ? 190 GLY B N 1 ATOM 5481 C CA . GLY B 1 190 ? -19.838 0.868 -31.856 1.00 31.77 ? 190 GLY B CA 1 ATOM 5482 C C . GLY B 1 190 ? -18.856 0.488 -32.950 1.00 31.89 ? 190 GLY B C 1 ATOM 5483 O O . GLY B 1 190 ? -19.249 -0.015 -34.004 1.00 31.81 ? 190 GLY B O 1 ATOM 5484 N N . LEU B 1 191 ? -17.572 0.725 -32.704 1.00 31.78 ? 191 LEU B N 1 ATOM 5485 C CA . LEU B 1 191 ? -16.544 0.303 -33.640 1.00 31.96 ? 191 LEU B CA 1 ATOM 5486 C C . LEU B 1 191 ? -16.366 -1.214 -33.644 1.00 32.13 ? 191 LEU B C 1 ATOM 5487 O O . LEU B 1 191 ? -16.327 -1.830 -34.708 1.00 32.44 ? 191 LEU B O 1 ATOM 5488 C CB . LEU B 1 191 ? -15.208 0.972 -33.322 1.00 31.80 ? 191 LEU B CB 1 ATOM 5489 C CG . LEU B 1 191 ? -15.091 2.475 -33.550 1.00 32.05 ? 191 LEU B CG 1 ATOM 5490 C CD1 . LEU B 1 191 ? -13.829 2.984 -32.877 1.00 30.73 ? 191 LEU B CD1 1 ATOM 5491 C CD2 . LEU B 1 191 ? -15.095 2.810 -35.046 1.00 31.81 ? 191 LEU B CD2 1 ATOM 5492 N N . ILE B 1 192 ? -16.265 -1.809 -32.454 1.00 32.03 ? 192 ILE B N 1 ATOM 5493 C CA . ILE B 1 192 ? -15.857 -3.212 -32.330 1.00 31.75 ? 192 ILE B CA 1 ATOM 5494 C C . ILE B 1 192 ? -16.990 -4.192 -32.644 1.00 31.51 ? 192 ILE B C 1 ATOM 5495 O O . ILE B 1 192 ? -16.739 -5.286 -33.139 1.00 31.34 ? 192 ILE B O 1 ATOM 5496 C CB . ILE B 1 192 ? -15.203 -3.499 -30.945 1.00 31.83 ? 192 ILE B CB 1 ATOM 5497 C CG1 . ILE B 1 192 ? -13.953 -2.627 -30.773 1.00 31.77 ? 192 ILE B CG1 1 ATOM 5498 C CG2 . ILE B 1 192 ? -14.864 -5.005 -30.774 1.00 31.15 ? 192 ILE B CG2 1 ATOM 5499 C CD1 . ILE B 1 192 ? -13.386 -2.593 -29.352 1.00 32.03 ? 192 ILE B CD1 1 ATOM 5500 N N . HIS B 1 193 ? -18.228 -3.777 -32.394 1.00 31.32 ? 193 HIS B N 1 ATOM 5501 C CA . HIS B 1 193 ? -19.388 -4.667 -32.542 1.00 31.39 ? 193 HIS B CA 1 ATOM 5502 C C . HIS B 1 193 ? -20.014 -4.728 -33.950 1.00 31.10 ? 193 HIS B C 1 ATOM 5503 O O . HIS B 1 193 ? -21.046 -5.371 -34.150 1.00 31.04 ? 193 HIS B O 1 ATOM 5504 C CB . HIS B 1 193 ? -20.429 -4.372 -31.459 1.00 31.29 ? 193 HIS B CB 1 ATOM 5505 C CG . HIS B 1 193 ? -19.972 -4.740 -30.082 1.00 32.63 ? 193 HIS B CG 1 ATOM 5506 N ND1 . HIS B 1 193 ? -19.952 -6.042 -29.628 1.00 34.54 ? 193 HIS B ND1 1 ATOM 5507 C CD2 . HIS B 1 193 ? -19.501 -3.982 -29.063 1.00 33.26 ? 193 HIS B CD2 1 ATOM 5508 C CE1 . HIS B 1 193 ? -19.505 -6.069 -28.384 1.00 34.04 ? 193 HIS B CE1 1 ATOM 5509 N NE2 . HIS B 1 193 ? -19.220 -4.832 -28.019 1.00 33.79 ? 193 HIS B NE2 1 ATOM 5510 N N . TYR B 1 194 ? -19.383 -4.061 -34.912 1.00 30.91 ? 194 TYR B N 1 ATOM 5511 C CA . TYR B 1 194 ? -19.718 -4.221 -36.321 1.00 30.87 ? 194 TYR B CA 1 ATOM 5512 C C . TYR B 1 194 ? -19.047 -5.506 -36.812 1.00 30.96 ? 194 TYR B C 1 ATOM 5513 O O . TYR B 1 194 ? -17.833 -5.686 -36.649 1.00 31.26 ? 194 TYR B O 1 ATOM 5514 C CB . TYR B 1 194 ? -19.260 -2.991 -37.110 1.00 30.93 ? 194 TYR B CB 1 ATOM 5515 C CG . TYR B 1 194 ? -19.316 -3.110 -38.617 1.00 30.94 ? 194 TYR B CG 1 ATOM 5516 C CD1 . TYR B 1 194 ? -20.483 -3.514 -39.273 1.00 31.78 ? 194 TYR B CD1 1 ATOM 5517 C CD2 . TYR B 1 194 ? -18.202 -2.792 -39.393 1.00 30.60 ? 194 TYR B CD2 1 ATOM 5518 C CE1 . TYR B 1 194 ? -20.525 -3.620 -40.671 1.00 31.42 ? 194 TYR B CE1 1 ATOM 5519 C CE2 . TYR B 1 194 ? -18.236 -2.881 -40.784 1.00 30.81 ? 194 TYR B CE2 1 ATOM 5520 C CZ . TYR B 1 194 ? -19.394 -3.296 -41.417 1.00 31.34 ? 194 TYR B CZ 1 ATOM 5521 O OH . TYR B 1 194 ? -19.413 -3.382 -42.793 1.00 32.14 ? 194 TYR B OH 1 ATOM 5522 N N . ALA B 1 195 ? -19.846 -6.393 -37.407 1.00 30.73 ? 195 ALA B N 1 ATOM 5523 C CA . ALA B 1 195 ? -19.456 -7.789 -37.633 1.00 30.48 ? 195 ALA B CA 1 ATOM 5524 C C . ALA B 1 195 ? -18.058 -8.039 -38.202 1.00 30.43 ? 195 ALA B C 1 ATOM 5525 O O . ALA B 1 195 ? -17.311 -8.823 -37.617 1.00 30.83 ? 195 ALA B O 1 ATOM 5526 C CB . ALA B 1 195 ? -20.524 -8.540 -38.436 1.00 30.42 ? 195 ALA B CB 1 ATOM 5527 N N . PRO B 1 196 ? -17.691 -7.398 -39.335 1.00 30.40 ? 196 PRO B N 1 ATOM 5528 C CA . PRO B 1 196 ? -16.341 -7.720 -39.845 1.00 30.30 ? 196 PRO B CA 1 ATOM 5529 C C . PRO B 1 196 ? -15.183 -7.133 -39.027 1.00 30.29 ? 196 PRO B C 1 ATOM 5530 O O . PRO B 1 196 ? -14.062 -7.653 -39.097 1.00 30.46 ? 196 PRO B O 1 ATOM 5531 C CB . PRO B 1 196 ? -16.340 -7.181 -41.280 1.00 29.90 ? 196 PRO B CB 1 ATOM 5532 C CG . PRO B 1 196 ? -17.469 -6.230 -41.359 1.00 30.22 ? 196 PRO B CG 1 ATOM 5533 C CD . PRO B 1 196 ? -18.468 -6.580 -40.287 1.00 30.47 ? 196 PRO B CD 1 ATOM 5534 N N . VAL B 1 197 ? -15.445 -6.077 -38.263 1.00 30.19 ? 197 VAL B N 1 ATOM 5535 C CA . VAL B 1 197 ? -14.443 -5.570 -37.324 1.00 30.34 ? 197 VAL B CA 1 ATOM 5536 C C . VAL B 1 197 ? -14.306 -6.542 -36.141 1.00 30.49 ? 197 VAL B C 1 ATOM 5537 O O . VAL B 1 197 ? -13.185 -6.845 -35.709 1.00 30.39 ? 197 VAL B O 1 ATOM 5538 C CB . VAL B 1 197 ? -14.757 -4.134 -36.825 1.00 30.31 ? 197 VAL B CB 1 ATOM 5539 C CG1 . VAL B 1 197 ? -13.705 -3.670 -35.824 1.00 30.33 ? 197 VAL B CG1 1 ATOM 5540 C CG2 . VAL B 1 197 ? -14.827 -3.164 -37.991 1.00 29.58 ? 197 VAL B CG2 1 ATOM 5541 N N . PHE B 1 198 ? -15.450 -7.034 -35.650 1.00 30.41 ? 198 PHE B N 1 ATOM 5542 C CA . PHE B 1 198 ? -15.504 -7.988 -34.542 1.00 30.34 ? 198 PHE B CA 1 ATOM 5543 C C . PHE B 1 198 ? -14.600 -9.187 -34.804 1.00 30.33 ? 198 PHE B C 1 ATOM 5544 O O . PHE B 1 198 ? -13.752 -9.513 -33.977 1.00 30.28 ? 198 PHE B O 1 ATOM 5545 C CB . PHE B 1 198 ? -16.956 -8.421 -34.265 1.00 30.56 ? 198 PHE B CB 1 ATOM 5546 C CG . PHE B 1 198 ? -17.118 -9.306 -33.045 1.00 30.80 ? 198 PHE B CG 1 ATOM 5547 C CD1 . PHE B 1 198 ? -16.983 -8.783 -31.761 1.00 30.50 ? 198 PHE B CD1 1 ATOM 5548 C CD2 . PHE B 1 198 ? -17.415 -10.662 -33.188 1.00 31.23 ? 198 PHE B CD2 1 ATOM 5549 C CE1 . PHE B 1 198 ? -17.130 -9.598 -30.639 1.00 30.72 ? 198 PHE B CE1 1 ATOM 5550 C CE2 . PHE B 1 198 ? -17.567 -11.487 -32.076 1.00 31.44 ? 198 PHE B CE2 1 ATOM 5551 C CZ . PHE B 1 198 ? -17.427 -10.951 -30.794 1.00 31.15 ? 198 PHE B CZ 1 ATOM 5552 N N . ARG B 1 199 ? -14.766 -9.824 -35.962 1.00 30.39 ? 199 ARG B N 1 ATOM 5553 C CA . ARG B 1 199 ? -13.900 -10.938 -36.359 1.00 30.57 ? 199 ARG B CA 1 ATOM 5554 C C . ARG B 1 199 ? -12.422 -10.536 -36.381 1.00 30.67 ? 199 ARG B C 1 ATOM 5555 O O . ARG B 1 199 ? -11.569 -11.257 -35.862 1.00 30.79 ? 199 ARG B O 1 ATOM 5556 C CB . ARG B 1 199 ? -14.302 -11.484 -37.731 1.00 30.65 ? 199 ARG B CB 1 ATOM 5557 C CG . ARG B 1 199 ? -15.649 -12.166 -37.765 1.00 30.65 ? 199 ARG B CG 1 ATOM 5558 C CD . ARG B 1 199 ? -16.046 -12.540 -39.187 1.00 31.76 ? 199 ARG B CD 1 ATOM 5559 N NE . ARG B 1 199 ? -17.499 -12.556 -39.292 1.00 32.88 ? 199 ARG B NE 1 ATOM 5560 C CZ . ARG B 1 199 ? -18.221 -11.667 -39.965 1.00 33.11 ? 199 ARG B CZ 1 ATOM 5561 N NH1 . ARG B 1 199 ? -17.631 -10.696 -40.644 1.00 31.69 ? 199 ARG B NH1 1 ATOM 5562 N NH2 . ARG B 1 199 ? -19.545 -11.763 -39.967 1.00 35.04 ? 199 ARG B NH2 1 ATOM 5563 N N . ASP B 1 200 ? -12.128 -9.387 -36.989 1.00 30.74 ? 200 ASP B N 1 ATOM 5564 C CA . ASP B 1 200 ? -10.755 -8.890 -37.085 1.00 30.67 ? 200 ASP B CA 1 ATOM 5565 C C . ASP B 1 200 ? -10.179 -8.576 -35.708 1.00 30.22 ? 200 ASP B C 1 ATOM 5566 O O . ASP B 1 200 ? -9.018 -8.888 -35.435 1.00 30.19 ? 200 ASP B O 1 ATOM 5567 C CB . ASP B 1 200 ? -10.683 -7.657 -37.989 1.00 31.14 ? 200 ASP B CB 1 ATOM 5568 C CG . ASP B 1 200 ? -10.744 -8.003 -39.485 1.00 32.59 ? 200 ASP B CG 1 ATOM 5569 O OD1 . ASP B 1 200 ? -10.438 -9.160 -39.877 1.00 33.92 ? 200 ASP B OD1 1 ATOM 5570 O OD2 . ASP B 1 200 ? -11.090 -7.094 -40.274 1.00 34.20 ? 200 ASP B OD2 1 ATOM 5571 N N . TYR B 1 201 ? -11.007 -7.981 -34.847 1.00 29.34 ? 201 TYR B N 1 ATOM 5572 C CA . TYR B 1 201 ? -10.634 -7.676 -33.473 1.00 28.42 ? 201 TYR B CA 1 ATOM 5573 C C . TYR B 1 201 ? -10.216 -8.929 -32.697 1.00 28.28 ? 201 TYR B C 1 ATOM 5574 O O . TYR B 1 201 ? -9.125 -8.973 -32.114 1.00 28.37 ? 201 TYR B O 1 ATOM 5575 C CB . TYR B 1 201 ? -11.784 -6.968 -32.745 1.00 28.32 ? 201 TYR B CB 1 ATOM 5576 C CG . TYR B 1 201 ? -11.380 -6.462 -31.378 1.00 27.86 ? 201 TYR B CG 1 ATOM 5577 C CD1 . TYR B 1 201 ? -11.392 -7.308 -30.260 1.00 25.99 ? 201 TYR B CD1 1 ATOM 5578 C CD2 . TYR B 1 201 ? -10.958 -5.139 -31.208 1.00 27.29 ? 201 TYR B CD2 1 ATOM 5579 C CE1 . TYR B 1 201 ? -10.997 -6.840 -29.013 1.00 26.73 ? 201 TYR B CE1 1 ATOM 5580 C CE2 . TYR B 1 201 ? -10.567 -4.664 -29.972 1.00 26.62 ? 201 TYR B CE2 1 ATOM 5581 C CZ . TYR B 1 201 ? -10.586 -5.511 -28.877 1.00 27.30 ? 201 TYR B CZ 1 ATOM 5582 O OH . TYR B 1 201 ? -10.189 -5.020 -27.645 1.00 28.33 ? 201 TYR B OH 1 ATOM 5583 N N . VAL B 1 202 ? -11.088 -9.939 -32.691 1.00 27.92 ? 202 VAL B N 1 ATOM 5584 C CA . VAL B 1 202 ? -10.828 -11.198 -32.000 1.00 27.47 ? 202 VAL B CA 1 ATOM 5585 C C . VAL B 1 202 ? -9.515 -11.792 -32.484 1.00 27.63 ? 202 VAL B C 1 ATOM 5586 O O . VAL B 1 202 ? -8.657 -12.147 -31.669 1.00 27.55 ? 202 VAL B O 1 ATOM 5587 C CB . VAL B 1 202 ? -11.990 -12.220 -32.185 1.00 27.66 ? 202 VAL B CB 1 ATOM 5588 C CG1 . VAL B 1 202 ? -11.612 -13.627 -31.615 1.00 26.97 ? 202 VAL B CG1 1 ATOM 5589 C CG2 . VAL B 1 202 ? -13.278 -11.700 -31.533 1.00 27.02 ? 202 VAL B CG2 1 ATOM 5590 N N . PHE B 1 203 ? -9.369 -11.876 -33.810 1.00 27.48 ? 203 PHE B N 1 ATOM 5591 C CA . PHE B 1 203 ? -8.176 -12.412 -34.455 1.00 27.54 ? 203 PHE B CA 1 ATOM 5592 C C . PHE B 1 203 ? -6.911 -11.643 -34.064 1.00 27.72 ? 203 PHE B C 1 ATOM 5593 O O . PHE B 1 203 ? -5.878 -12.244 -33.751 1.00 27.64 ? 203 PHE B O 1 ATOM 5594 C CB . PHE B 1 203 ? -8.350 -12.408 -35.979 1.00 27.70 ? 203 PHE B CB 1 ATOM 5595 C CG . PHE B 1 203 ? -7.368 -13.276 -36.702 1.00 27.68 ? 203 PHE B CG 1 ATOM 5596 C CD1 . PHE B 1 203 ? -6.176 -12.745 -37.179 1.00 28.15 ? 203 PHE B CD1 1 ATOM 5597 C CD2 . PHE B 1 203 ? -7.632 -14.639 -36.898 1.00 28.69 ? 203 PHE B CD2 1 ATOM 5598 C CE1 . PHE B 1 203 ? -5.247 -13.559 -37.850 1.00 29.50 ? 203 PHE B CE1 1 ATOM 5599 C CE2 . PHE B 1 203 ? -6.718 -15.471 -37.568 1.00 28.60 ? 203 PHE B CE2 1 ATOM 5600 C CZ . PHE B 1 203 ? -5.518 -14.928 -38.046 1.00 29.04 ? 203 PHE B CZ 1 ATOM 5601 N N . ARG B 1 204 ? -7.000 -10.315 -34.058 1.00 27.93 ? 204 ARG B N 1 ATOM 5602 C CA . ARG B 1 204 ? -5.855 -9.491 -33.715 1.00 28.27 ? 204 ARG B CA 1 ATOM 5603 C C . ARG B 1 204 ? -5.412 -9.636 -32.260 1.00 28.34 ? 204 ARG B C 1 ATOM 5604 O O . ARG B 1 204 ? -4.205 -9.612 -31.977 1.00 28.24 ? 204 ARG B O 1 ATOM 5605 C CB . ARG B 1 204 ? -6.105 -8.025 -34.040 1.00 28.41 ? 204 ARG B CB 1 ATOM 5606 C CG . ARG B 1 204 ? -4.805 -7.274 -34.210 1.00 30.30 ? 204 ARG B CG 1 ATOM 5607 C CD . ARG B 1 204 ? -5.020 -5.845 -34.524 1.00 34.90 ? 204 ARG B CD 1 ATOM 5608 N NE . ARG B 1 204 ? -3.785 -5.099 -34.322 1.00 40.58 ? 204 ARG B NE 1 ATOM 5609 C CZ . ARG B 1 204 ? -2.875 -4.871 -35.266 1.00 43.35 ? 204 ARG B CZ 1 ATOM 5610 N NH1 . ARG B 1 204 ? -3.049 -5.326 -36.502 1.00 44.26 ? 204 ARG B NH1 1 ATOM 5611 N NH2 . ARG B 1 204 ? -1.785 -4.177 -34.970 1.00 44.91 ? 204 ARG B NH2 1 ATOM 5612 N N . SER B 1 205 ? -6.371 -9.782 -31.343 1.00 28.34 ? 205 SER B N 1 ATOM 5613 C CA . SER B 1 205 ? -6.037 -9.999 -29.932 1.00 28.44 ? 205 SER B CA 1 ATOM 5614 C C . SER B 1 205 ? -5.248 -11.290 -29.730 1.00 28.70 ? 205 SER B C 1 ATOM 5615 O O . SER B 1 205 ? -4.366 -11.359 -28.868 1.00 28.62 ? 205 SER B O 1 ATOM 5616 C CB . SER B 1 205 ? -7.280 -9.952 -29.037 1.00 28.20 ? 205 SER B CB 1 ATOM 5617 O OG . SER B 1 205 ? -8.062 -11.122 -29.149 1.00 27.85 ? 205 SER B OG 1 ATOM 5618 N N . MET B 1 206 ? -5.552 -12.306 -30.533 1.00 29.34 ? 206 MET B N 1 ATOM 5619 C CA . MET B 1 206 ? -4.748 -13.529 -30.532 1.00 30.12 ? 206 MET B CA 1 ATOM 5620 C C . MET B 1 206 ? -3.348 -13.272 -31.100 1.00 30.91 ? 206 MET B C 1 ATOM 5621 O O . MET B 1 206 ? -2.354 -13.751 -30.536 1.00 30.96 ? 206 MET B O 1 ATOM 5622 C CB . MET B 1 206 ? -5.460 -14.670 -31.262 1.00 30.07 ? 206 MET B CB 1 ATOM 5623 C CG . MET B 1 206 ? -6.624 -15.239 -30.467 1.00 29.42 ? 206 MET B CG 1 ATOM 5624 S SD . MET B 1 206 ? -7.610 -16.499 -31.290 1.00 30.46 ? 206 MET B SD 1 ATOM 5625 C CE . MET B 1 206 ? -8.380 -15.527 -32.591 1.00 27.67 ? 206 MET B CE 1 ATOM 5626 N N . GLN B 1 207 ? -3.275 -12.498 -32.188 1.00 31.58 ? 207 GLN B N 1 ATOM 5627 C CA . GLN B 1 207 ? -1.988 -12.087 -32.753 1.00 32.70 ? 207 GLN B CA 1 ATOM 5628 C C . GLN B 1 207 ? -1.115 -11.393 -31.719 1.00 33.02 ? 207 GLN B C 1 ATOM 5629 O O . GLN B 1 207 ? 0.058 -11.749 -31.562 1.00 33.35 ? 207 GLN B O 1 ATOM 5630 C CB . GLN B 1 207 ? -2.163 -11.167 -33.966 1.00 32.96 ? 207 GLN B CB 1 ATOM 5631 C CG . GLN B 1 207 ? -2.492 -11.885 -35.254 1.00 34.39 ? 207 GLN B CG 1 ATOM 5632 C CD . GLN B 1 207 ? -2.797 -10.933 -36.393 1.00 36.30 ? 207 GLN B CD 1 ATOM 5633 O OE1 . GLN B 1 207 ? -3.625 -10.023 -36.274 1.00 37.57 ? 207 GLN B OE1 1 ATOM 5634 N NE2 . GLN B 1 207 ? -2.132 -11.143 -37.513 1.00 37.05 ? 207 GLN B NE2 1 ATOM 5635 N N . GLU B 1 208 ? -1.689 -10.414 -31.015 1.00 33.21 ? 208 GLU B N 1 ATOM 5636 C CA . GLU B 1 208 ? -0.937 -9.627 -30.022 1.00 33.52 ? 208 GLU B CA 1 ATOM 5637 C C . GLU B 1 208 ? -0.464 -10.440 -28.820 1.00 32.90 ? 208 GLU B C 1 ATOM 5638 O O . GLU B 1 208 ? 0.673 -10.281 -28.383 1.00 33.00 ? 208 GLU B O 1 ATOM 5639 C CB . GLU B 1 208 ? -1.703 -8.369 -29.590 1.00 33.78 ? 208 GLU B CB 1 ATOM 5640 C CG . GLU B 1 208 ? -1.776 -7.322 -30.710 1.00 36.40 ? 208 GLU B CG 1 ATOM 5641 C CD . GLU B 1 208 ? -2.334 -5.970 -30.282 1.00 39.43 ? 208 GLU B CD 1 ATOM 5642 O OE1 . GLU B 1 208 ? -2.381 -5.676 -29.070 1.00 40.26 ? 208 GLU B OE1 1 ATOM 5643 O OE2 . GLU B 1 208 ? -2.712 -5.185 -31.182 1.00 42.08 ? 208 GLU B OE2 1 ATOM 5644 N N . PHE B 1 209 ? -1.313 -11.335 -28.318 1.00 32.15 ? 209 PHE B N 1 ATOM 5645 C CA . PHE B 1 209 ? -0.906 -12.206 -27.227 1.00 31.59 ? 209 PHE B CA 1 ATOM 5646 C C . PHE B 1 209 ? 0.046 -13.305 -27.687 1.00 31.78 ? 209 PHE B C 1 ATOM 5647 O O . PHE B 1 209 ? 0.968 -13.669 -26.952 1.00 31.62 ? 209 PHE B O 1 ATOM 5648 C CB . PHE B 1 209 ? -2.121 -12.763 -26.477 1.00 31.35 ? 209 PHE B CB 1 ATOM 5649 C CG . PHE B 1 209 ? -2.674 -11.812 -25.448 1.00 30.09 ? 209 PHE B CG 1 ATOM 5650 C CD1 . PHE B 1 209 ? -2.466 -12.036 -24.097 1.00 28.81 ? 209 PHE B CD1 1 ATOM 5651 C CD2 . PHE B 1 209 ? -3.375 -10.676 -25.835 1.00 29.04 ? 209 PHE B CD2 1 ATOM 5652 C CE1 . PHE B 1 209 ? -2.958 -11.161 -23.150 1.00 27.86 ? 209 PHE B CE1 1 ATOM 5653 C CE2 . PHE B 1 209 ? -3.869 -9.791 -24.897 1.00 28.91 ? 209 PHE B CE2 1 ATOM 5654 C CZ . PHE B 1 209 ? -3.660 -10.033 -23.550 1.00 28.71 ? 209 PHE B CZ 1 ATOM 5655 N N . TYR B 1 210 ? -0.162 -13.822 -28.898 1.00 31.84 ? 210 TYR B N 1 ATOM 5656 C CA . TYR B 1 210 ? 0.762 -14.808 -29.461 1.00 32.25 ? 210 TYR B CA 1 ATOM 5657 C C . TYR B 1 210 ? 2.145 -14.194 -29.663 1.00 32.28 ? 210 TYR B C 1 ATOM 5658 O O . TYR B 1 210 ? 3.157 -14.818 -29.369 1.00 31.76 ? 210 TYR B O 1 ATOM 5659 C CB . TYR B 1 210 ? 0.245 -15.371 -30.788 1.00 32.53 ? 210 TYR B CB 1 ATOM 5660 C CG . TYR B 1 210 ? 1.154 -16.421 -31.387 1.00 32.89 ? 210 TYR B CG 1 ATOM 5661 C CD1 . TYR B 1 210 ? 1.098 -17.748 -30.948 1.00 33.70 ? 210 TYR B CD1 1 ATOM 5662 C CD2 . TYR B 1 210 ? 2.084 -16.091 -32.381 1.00 33.65 ? 210 TYR B CD2 1 ATOM 5663 C CE1 . TYR B 1 210 ? 1.937 -18.723 -31.485 1.00 34.36 ? 210 TYR B CE1 1 ATOM 5664 C CE2 . TYR B 1 210 ? 2.933 -17.067 -32.926 1.00 34.33 ? 210 TYR B CE2 1 ATOM 5665 C CZ . TYR B 1 210 ? 2.844 -18.376 -32.473 1.00 34.72 ? 210 TYR B CZ 1 ATOM 5666 O OH . TYR B 1 210 ? 3.661 -19.345 -32.996 1.00 36.54 ? 210 TYR B OH 1 ATOM 5667 N N . GLU B 1 211 ? 2.166 -12.967 -30.170 1.00 32.71 ? 211 GLU B N 1 ATOM 5668 C CA . GLU B 1 211 ? 3.393 -12.199 -30.329 1.00 33.47 ? 211 GLU B CA 1 ATOM 5669 C C . GLU B 1 211 ? 4.102 -11.976 -28.973 1.00 32.84 ? 211 GLU B C 1 ATOM 5670 O O . GLU B 1 211 ? 5.323 -11.901 -28.931 1.00 32.99 ? 211 GLU B O 1 ATOM 5671 C CB . GLU B 1 211 ? 3.073 -10.875 -31.039 1.00 34.14 ? 211 GLU B CB 1 ATOM 5672 C CG . GLU B 1 211 ? 4.266 -10.078 -31.553 1.00 38.38 ? 211 GLU B CG 1 ATOM 5673 C CD . GLU B 1 211 ? 4.897 -9.171 -30.498 1.00 44.43 ? 211 GLU B CD 1 ATOM 5674 O OE1 . GLU B 1 211 ? 4.239 -8.869 -29.470 1.00 47.87 ? 211 GLU B OE1 1 ATOM 5675 O OE2 . GLU B 1 211 ? 6.061 -8.754 -30.699 1.00 46.71 ? 211 GLU B OE2 1 ATOM 5676 N N . ASP B 1 212 ? 3.336 -11.891 -27.879 1.00 32.11 ? 212 ASP B N 1 ATOM 5677 C CA . ASP B 1 212 ? 3.895 -11.709 -26.536 1.00 31.30 ? 212 ASP B CA 1 ATOM 5678 C C . ASP B 1 212 ? 4.263 -13.052 -25.908 1.00 30.94 ? 212 ASP B C 1 ATOM 5679 O O . ASP B 1 212 ? 4.634 -13.102 -24.732 1.00 30.82 ? 212 ASP B O 1 ATOM 5680 C CB . ASP B 1 212 ? 2.916 -10.931 -25.633 1.00 31.49 ? 212 ASP B CB 1 ATOM 5681 C CG . ASP B 1 212 ? 3.597 -10.289 -24.401 1.00 31.85 ? 212 ASP B CG 1 ATOM 5682 O OD1 . ASP B 1 212 ? 4.617 -9.579 -24.557 1.00 32.87 ? 212 ASP B OD1 1 ATOM 5683 O OD2 . ASP B 1 212 ? 3.093 -10.472 -23.272 1.00 30.59 ? 212 ASP B OD2 1 ATOM 5684 N N . ASN B 1 213 ? 4.172 -14.129 -26.698 1.00 30.32 ? 213 ASN B N 1 ATOM 5685 C CA . ASN B 1 213 ? 4.526 -15.493 -26.260 1.00 29.86 ? 213 ASN B CA 1 ATOM 5686 C C . ASN B 1 213 ? 3.546 -16.048 -25.197 1.00 29.29 ? 213 ASN B C 1 ATOM 5687 O O . ASN B 1 213 ? 3.934 -16.714 -24.224 1.00 29.06 ? 213 ASN B O 1 ATOM 5688 C CB . ASN B 1 213 ? 5.996 -15.553 -25.801 1.00 30.01 ? 213 ASN B CB 1 ATOM 5689 C CG . ASN B 1 213 ? 6.592 -16.949 -25.894 1.00 31.32 ? 213 ASN B CG 1 ATOM 5690 O OD1 . ASN B 1 213 ? 5.889 -17.932 -26.159 1.00 33.17 ? 213 ASN B OD1 1 ATOM 5691 N ND2 . ASN B 1 213 ? 7.903 -17.045 -25.664 1.00 31.43 ? 213 ASN B ND2 1 ATOM 5692 N N . VAL B 1 214 ? 2.269 -15.742 -25.408 1.00 28.53 ? 214 VAL B N 1 ATOM 5693 C CA . VAL B 1 214 ? 1.165 -16.261 -24.602 1.00 27.99 ? 214 VAL B CA 1 ATOM 5694 C C . VAL B 1 214 ? 0.324 -17.147 -25.522 1.00 28.08 ? 214 VAL B C 1 ATOM 5695 O O . VAL B 1 214 ? -0.018 -16.737 -26.637 1.00 28.05 ? 214 VAL B O 1 ATOM 5696 C CB . VAL B 1 214 ? 0.308 -15.098 -24.014 1.00 27.83 ? 214 VAL B CB 1 ATOM 5697 C CG1 . VAL B 1 214 ? -0.873 -15.622 -23.220 1.00 26.90 ? 214 VAL B CG1 1 ATOM 5698 C CG2 . VAL B 1 214 ? 1.173 -14.193 -23.146 1.00 27.25 ? 214 VAL B CG2 1 ATOM 5699 N N . LEU B 1 215 ? -0.014 -18.349 -25.067 1.00 28.06 ? 215 LEU B N 1 ATOM 5700 C CA . LEU B 1 215 ? -0.582 -19.353 -25.976 1.00 28.41 ? 215 LEU B CA 1 ATOM 5701 C C . LEU B 1 215 ? -2.065 -19.676 -25.770 1.00 28.64 ? 215 LEU B C 1 ATOM 5702 O O . LEU B 1 215 ? -2.672 -20.386 -26.578 1.00 28.89 ? 215 LEU B O 1 ATOM 5703 C CB . LEU B 1 215 ? 0.266 -20.637 -25.952 1.00 28.50 ? 215 LEU B CB 1 ATOM 5704 C CG . LEU B 1 215 ? 1.719 -20.477 -26.419 1.00 28.01 ? 215 LEU B CG 1 ATOM 5705 C CD1 . LEU B 1 215 ? 2.504 -21.757 -26.165 1.00 28.41 ? 215 LEU B CD1 1 ATOM 5706 C CD2 . LEU B 1 215 ? 1.784 -20.081 -27.877 1.00 27.50 ? 215 LEU B CD2 1 ATOM 5707 N N . TYR B 1 216 ? -2.650 -19.149 -24.700 1.00 28.80 ? 216 TYR B N 1 ATOM 5708 C CA . TYR B 1 216 ? -4.042 -19.443 -24.363 1.00 28.58 ? 216 TYR B CA 1 ATOM 5709 C C . TYR B 1 216 ? -4.687 -18.254 -23.667 1.00 28.51 ? 216 TYR B C 1 ATOM 5710 O O . TYR B 1 216 ? -4.021 -17.520 -22.932 1.00 28.67 ? 216 TYR B O 1 ATOM 5711 C CB . TYR B 1 216 ? -4.118 -20.699 -23.496 1.00 28.49 ? 216 TYR B CB 1 ATOM 5712 C CG . TYR B 1 216 ? -5.500 -21.099 -23.042 1.00 28.44 ? 216 TYR B CG 1 ATOM 5713 C CD1 . TYR B 1 216 ? -6.480 -21.483 -23.959 1.00 28.67 ? 216 TYR B CD1 1 ATOM 5714 C CD2 . TYR B 1 216 ? -5.821 -21.120 -21.688 1.00 28.34 ? 216 TYR B CD2 1 ATOM 5715 C CE1 . TYR B 1 216 ? -7.757 -21.851 -23.537 1.00 28.33 ? 216 TYR B CE1 1 ATOM 5716 C CE2 . TYR B 1 216 ? -7.086 -21.495 -21.251 1.00 28.05 ? 216 TYR B CE2 1 ATOM 5717 C CZ . TYR B 1 216 ? -8.051 -21.855 -22.178 1.00 28.32 ? 216 TYR B CZ 1 ATOM 5718 O OH . TYR B 1 216 ? -9.297 -22.229 -21.732 1.00 28.38 ? 216 TYR B OH 1 ATOM 5719 N N . MET B 1 217 ? -5.980 -18.063 -23.925 1.00 28.29 ? 217 MET B N 1 ATOM 5720 C CA . MET B 1 217 ? -6.727 -16.922 -23.414 1.00 28.09 ? 217 MET B CA 1 ATOM 5721 C C . MET B 1 217 ? -8.127 -17.315 -22.922 1.00 27.96 ? 217 MET B C 1 ATOM 5722 O O . MET B 1 217 ? -8.879 -17.970 -23.629 1.00 27.88 ? 217 MET B O 1 ATOM 5723 C CB . MET B 1 217 ? -6.868 -15.851 -24.502 1.00 28.11 ? 217 MET B CB 1 ATOM 5724 C CG . MET B 1 217 ? -5.572 -15.201 -24.975 1.00 27.82 ? 217 MET B CG 1 ATOM 5725 S SD . MET B 1 217 ? -5.913 -14.002 -26.296 1.00 28.16 ? 217 MET B SD 1 ATOM 5726 C CE . MET B 1 217 ? -5.848 -15.097 -27.665 1.00 30.78 ? 217 MET B CE 1 ATOM 5727 N N . GLU B 1 218 ? -8.468 -16.906 -21.707 1.00 27.97 ? 218 GLU B N 1 ATOM 5728 C CA . GLU B 1 218 ? -9.855 -16.967 -21.239 1.00 28.19 ? 218 GLU B CA 1 ATOM 5729 C C . GLU B 1 218 ? -10.369 -15.543 -21.053 1.00 28.01 ? 218 GLU B C 1 ATOM 5730 O O . GLU B 1 218 ? -9.735 -14.740 -20.365 1.00 27.94 ? 218 GLU B O 1 ATOM 5731 C CB . GLU B 1 218 ? -9.981 -17.804 -19.960 1.00 28.09 ? 218 GLU B CB 1 ATOM 5732 C CG . GLU B 1 218 ? -9.634 -19.270 -20.200 1.00 28.56 ? 218 GLU B CG 1 ATOM 5733 C CD . GLU B 1 218 ? -9.917 -20.161 -19.014 1.00 29.81 ? 218 GLU B CD 1 ATOM 5734 O OE1 . GLU B 1 218 ? -10.191 -19.634 -17.913 1.00 29.95 ? 218 GLU B OE1 1 ATOM 5735 O OE2 . GLU B 1 218 ? -9.863 -21.402 -19.181 1.00 30.59 ? 218 GLU B OE2 1 ATOM 5736 N N . ILE B 1 219 ? -11.506 -15.238 -21.684 1.00 27.81 ? 219 ILE B N 1 ATOM 5737 C CA . ILE B 1 219 ? -11.987 -13.857 -21.836 1.00 27.59 ? 219 ILE B CA 1 ATOM 5738 C C . ILE B 1 219 ? -13.349 -13.640 -21.169 1.00 27.56 ? 219 ILE B C 1 ATOM 5739 O O . ILE B 1 219 ? -14.301 -14.363 -21.473 1.00 27.77 ? 219 ILE B O 1 ATOM 5740 C CB . ILE B 1 219 ? -12.098 -13.495 -23.354 1.00 27.75 ? 219 ILE B CB 1 ATOM 5741 C CG1 . ILE B 1 219 ? -10.718 -13.519 -24.022 1.00 27.53 ? 219 ILE B CG1 1 ATOM 5742 C CG2 . ILE B 1 219 ? -12.783 -12.145 -23.570 1.00 27.78 ? 219 ILE B CG2 1 ATOM 5743 C CD1 . ILE B 1 219 ? -10.764 -13.511 -25.534 1.00 27.40 ? 219 ILE B CD1 1 ATOM 5744 N N . ARG B 1 220 ? -13.445 -12.656 -20.267 1.00 27.28 ? 220 ARG B N 1 ATOM 5745 C CA . ARG B 1 220 ? -14.750 -12.179 -19.773 1.00 26.97 ? 220 ARG B CA 1 ATOM 5746 C C . ARG B 1 220 ? -15.441 -11.371 -20.863 1.00 27.02 ? 220 ARG B C 1 ATOM 5747 O O . ARG B 1 220 ? -14.949 -10.310 -21.250 1.00 26.63 ? 220 ARG B O 1 ATOM 5748 C CB . ARG B 1 220 ? -14.596 -11.294 -18.530 1.00 27.09 ? 220 ARG B CB 1 ATOM 5749 C CG . ARG B 1 220 ? -14.789 -11.983 -17.185 1.00 26.53 ? 220 ARG B CG 1 ATOM 5750 C CD . ARG B 1 220 ? -13.569 -12.811 -16.826 1.00 25.58 ? 220 ARG B CD 1 ATOM 5751 N NE . ARG B 1 220 ? -13.476 -13.123 -15.410 1.00 23.71 ? 220 ARG B NE 1 ATOM 5752 C CZ . ARG B 1 220 ? -12.402 -13.672 -14.842 1.00 23.98 ? 220 ARG B CZ 1 ATOM 5753 N NH1 . ARG B 1 220 ? -11.339 -13.970 -15.580 1.00 22.36 ? 220 ARG B NH1 1 ATOM 5754 N NH2 . ARG B 1 220 ? -12.386 -13.917 -13.532 1.00 24.18 ? 220 ARG B NH2 1 ATOM 5755 N N . ALA B 1 221 ? -16.580 -11.868 -21.342 1.00 27.09 ? 221 ALA B N 1 ATOM 5756 C CA . ALA B 1 221 ? -17.266 -11.284 -22.488 1.00 27.23 ? 221 ALA B CA 1 ATOM 5757 C C . ALA B 1 221 ? -18.717 -10.958 -22.182 1.00 27.76 ? 221 ALA B C 1 ATOM 5758 O O . ALA B 1 221 ? -19.480 -11.830 -21.752 1.00 27.34 ? 221 ALA B O 1 ATOM 5759 C CB . ALA B 1 221 ? -17.185 -12.226 -23.680 1.00 26.91 ? 221 ALA B CB 1 ATOM 5760 N N . ARG B 1 222 ? -19.096 -9.703 -22.423 1.00 28.53 ? 222 ARG B N 1 ATOM 5761 C CA . ARG B 1 222 ? -20.483 -9.252 -22.258 1.00 29.61 ? 222 ARG B CA 1 ATOM 5762 C C . ARG B 1 222 ? -21.386 -9.842 -23.340 1.00 29.30 ? 222 ARG B C 1 ATOM 5763 O O . ARG B 1 222 ? -22.599 -9.950 -23.144 1.00 29.19 ? 222 ARG B O 1 ATOM 5764 C CB . ARG B 1 222 ? -20.591 -7.726 -22.333 1.00 29.90 ? 222 ARG B CB 1 ATOM 5765 C CG . ARG B 1 222 ? -19.847 -6.900 -21.289 1.00 33.33 ? 222 ARG B CG 1 ATOM 5766 C CD . ARG B 1 222 ? -20.604 -6.697 -19.966 1.00 40.00 ? 222 ARG B CD 1 ATOM 5767 N NE . ARG B 1 222 ? -22.062 -6.868 -20.044 1.00 45.93 ? 222 ARG B NE 1 ATOM 5768 C CZ . ARG B 1 222 ? -22.937 -5.926 -20.408 1.00 49.03 ? 222 ARG B CZ 1 ATOM 5769 N NH1 . ARG B 1 222 ? -22.526 -4.710 -20.772 1.00 50.54 ? 222 ARG B NH1 1 ATOM 5770 N NH2 . ARG B 1 222 ? -24.237 -6.212 -20.429 1.00 49.90 ? 222 ARG B NH2 1 ATOM 5771 N N . LEU B 1 223 ? -20.784 -10.218 -24.471 1.00 29.17 ? 223 LEU B N 1 ATOM 5772 C CA . LEU B 1 223 ? -21.509 -10.760 -25.626 1.00 29.40 ? 223 LEU B CA 1 ATOM 5773 C C . LEU B 1 223 ? -22.640 -9.832 -26.061 1.00 29.76 ? 223 LEU B C 1 ATOM 5774 O O . LEU B 1 223 ? -23.762 -10.272 -26.286 1.00 29.89 ? 223 LEU B O 1 ATOM 5775 C CB . LEU B 1 223 ? -22.073 -12.163 -25.342 1.00 29.19 ? 223 LEU B CB 1 ATOM 5776 C CG . LEU B 1 223 ? -21.164 -13.314 -24.926 1.00 28.72 ? 223 LEU B CG 1 ATOM 5777 C CD1 . LEU B 1 223 ? -22.027 -14.522 -24.652 1.00 28.04 ? 223 LEU B CD1 1 ATOM 5778 C CD2 . LEU B 1 223 ? -20.103 -13.612 -25.991 1.00 27.49 ? 223 LEU B CD2 1 ATOM 5779 N N . LEU B 1 224 ? -22.336 -8.543 -26.156 1.00 30.10 ? 224 LEU B N 1 ATOM 5780 C CA . LEU B 1 224 ? -23.293 -7.544 -26.608 1.00 30.54 ? 224 LEU B CA 1 ATOM 5781 C C . LEU B 1 224 ? -23.648 -7.854 -28.064 1.00 30.90 ? 224 LEU B C 1 ATOM 5782 O O . LEU B 1 224 ? -22.860 -8.511 -28.746 1.00 31.19 ? 224 LEU B O 1 ATOM 5783 C CB . LEU B 1 224 ? -22.681 -6.142 -26.494 1.00 30.34 ? 224 LEU B CB 1 ATOM 5784 C CG . LEU B 1 224 ? -22.699 -5.318 -25.190 1.00 30.49 ? 224 LEU B CG 1 ATOM 5785 C CD1 . LEU B 1 224 ? -24.089 -4.839 -24.837 1.00 31.07 ? 224 LEU B CD1 1 ATOM 5786 C CD2 . LEU B 1 224 ? -22.174 -6.039 -24.018 1.00 30.64 ? 224 LEU B CD2 1 ATOM 5787 N N . PRO B 1 225 ? -24.828 -7.402 -28.545 1.00 31.16 ? 225 PRO B N 1 ATOM 5788 C CA . PRO B 1 225 ? -25.199 -7.732 -29.932 1.00 31.41 ? 225 PRO B CA 1 ATOM 5789 C C . PRO B 1 225 ? -24.233 -7.193 -30.992 1.00 31.76 ? 225 PRO B C 1 ATOM 5790 O O . PRO B 1 225 ? -23.922 -5.998 -31.006 1.00 31.95 ? 225 PRO B O 1 ATOM 5791 C CB . PRO B 1 225 ? -26.593 -7.107 -30.100 1.00 31.32 ? 225 PRO B CB 1 ATOM 5792 C CG . PRO B 1 225 ? -26.791 -6.224 -28.916 1.00 31.41 ? 225 PRO B CG 1 ATOM 5793 C CD . PRO B 1 225 ? -25.938 -6.765 -27.817 1.00 30.95 ? 225 PRO B CD 1 ATOM 5794 N N . VAL B 1 226 ? -23.753 -8.087 -31.854 1.00 31.96 ? 226 VAL B N 1 ATOM 5795 C CA . VAL B 1 226 ? -22.929 -7.717 -33.001 1.00 32.06 ? 226 VAL B CA 1 ATOM 5796 C C . VAL B 1 226 ? -23.878 -7.397 -34.167 1.00 32.22 ? 226 VAL B C 1 ATOM 5797 O O . VAL B 1 226 ? -24.916 -8.051 -34.332 1.00 31.99 ? 226 VAL B O 1 ATOM 5798 C CB . VAL B 1 226 ? -21.918 -8.844 -33.356 1.00 32.14 ? 226 VAL B CB 1 ATOM 5799 C CG1 . VAL B 1 226 ? -21.035 -8.462 -34.545 1.00 32.08 ? 226 VAL B CG1 1 ATOM 5800 C CG2 . VAL B 1 226 ? -21.040 -9.165 -32.156 1.00 32.04 ? 226 VAL B CG2 1 ATOM 5801 N N . TYR B 1 227 ? -23.540 -6.378 -34.953 1.00 32.47 ? 227 TYR B N 1 ATOM 5802 C CA . TYR B 1 227 ? -24.473 -5.847 -35.956 1.00 32.75 ? 227 TYR B CA 1 ATOM 5803 C C . TYR B 1 227 ? -23.898 -5.761 -37.378 1.00 33.30 ? 227 TYR B C 1 ATOM 5804 O O . TYR B 1 227 ? -22.682 -5.730 -37.567 1.00 33.36 ? 227 TYR B O 1 ATOM 5805 C CB . TYR B 1 227 ? -25.054 -4.500 -35.502 1.00 32.24 ? 227 TYR B CB 1 ATOM 5806 C CG . TYR B 1 227 ? -24.063 -3.356 -35.516 1.00 31.91 ? 227 TYR B CG 1 ATOM 5807 C CD1 . TYR B 1 227 ? -23.992 -2.488 -36.605 1.00 31.06 ? 227 TYR B CD1 1 ATOM 5808 C CD2 . TYR B 1 227 ? -23.195 -3.139 -34.438 1.00 30.69 ? 227 TYR B CD2 1 ATOM 5809 C CE1 . TYR B 1 227 ? -23.081 -1.440 -36.631 1.00 31.18 ? 227 TYR B CE1 1 ATOM 5810 C CE2 . TYR B 1 227 ? -22.281 -2.099 -34.451 1.00 30.95 ? 227 TYR B CE2 1 ATOM 5811 C CZ . TYR B 1 227 ? -22.227 -1.249 -35.552 1.00 31.57 ? 227 TYR B CZ 1 ATOM 5812 O OH . TYR B 1 227 ? -21.328 -0.203 -35.583 1.00 31.42 ? 227 TYR B OH 1 ATOM 5813 N N . GLU B 1 228 ? -24.792 -5.719 -38.365 1.00 34.14 ? 228 GLU B N 1 ATOM 5814 C CA . GLU B 1 228 ? -24.410 -5.664 -39.783 1.00 35.00 ? 228 GLU B CA 1 ATOM 5815 C C . GLU B 1 228 ? -24.748 -4.299 -40.372 1.00 35.85 ? 228 GLU B C 1 ATOM 5816 O O . GLU B 1 228 ? -25.447 -3.514 -39.735 1.00 35.80 ? 228 GLU B O 1 ATOM 5817 C CB . GLU B 1 228 ? -25.130 -6.767 -40.573 1.00 34.62 ? 228 GLU B CB 1 ATOM 5818 C CG . GLU B 1 228 ? -24.950 -8.178 -40.014 1.00 33.52 ? 228 GLU B CG 1 ATOM 5819 C CD . GLU B 1 228 ? -23.621 -8.802 -40.377 1.00 32.64 ? 228 GLU B CD 1 ATOM 5820 O OE1 . GLU B 1 228 ? -22.830 -8.179 -41.107 1.00 30.41 ? 228 GLU B OE1 1 ATOM 5821 O OE2 . GLU B 1 228 ? -23.361 -9.936 -39.931 1.00 34.91 ? 228 GLU B OE2 1 ATOM 5822 N N . LEU B 1 229 ? -24.253 -4.028 -41.584 1.00 37.25 ? 229 LEU B N 1 ATOM 5823 C CA . LEU B 1 229 ? -24.541 -2.776 -42.302 1.00 38.63 ? 229 LEU B CA 1 ATOM 5824 C C . LEU B 1 229 ? -26.042 -2.551 -42.525 1.00 39.74 ? 229 LEU B C 1 ATOM 5825 O O . LEU B 1 229 ? -26.518 -1.413 -42.516 1.00 40.04 ? 229 LEU B O 1 ATOM 5826 C CB . LEU B 1 229 ? -23.817 -2.726 -43.649 1.00 38.50 ? 229 LEU B CB 1 ATOM 5827 C CG . LEU B 1 229 ? -22.385 -2.190 -43.761 1.00 38.44 ? 229 LEU B CG 1 ATOM 5828 C CD1 . LEU B 1 229 ? -22.002 -2.063 -45.228 1.00 37.44 ? 229 LEU B CD1 1 ATOM 5829 C CD2 . LEU B 1 229 ? -22.202 -0.846 -43.066 1.00 38.77 ? 229 LEU B CD2 1 ATOM 5830 N N . SER B 1 230 ? -26.773 -3.646 -42.723 1.00 40.83 ? 230 SER B N 1 ATOM 5831 C CA . SER B 1 230 ? -28.228 -3.619 -42.849 1.00 41.90 ? 230 SER B CA 1 ATOM 5832 C C . SER B 1 230 ? -28.927 -3.077 -41.606 1.00 42.38 ? 230 SER B C 1 ATOM 5833 O O . SER B 1 230 ? -29.989 -2.458 -41.707 1.00 42.73 ? 230 SER B O 1 ATOM 5834 C CB . SER B 1 230 ? -28.740 -5.028 -43.135 1.00 41.98 ? 230 SER B CB 1 ATOM 5835 O OG . SER B 1 230 ? -28.201 -5.965 -42.216 1.00 42.83 ? 230 SER B OG 1 ATOM 5836 N N . GLY B 1 231 ? -28.330 -3.319 -40.440 1.00 42.87 ? 231 GLY B N 1 ATOM 5837 C CA . GLY B 1 231 ? -28.922 -2.928 -39.164 1.00 43.03 ? 231 GLY B CA 1 ATOM 5838 C C . GLY B 1 231 ? -29.390 -4.115 -38.346 1.00 43.24 ? 231 GLY B C 1 ATOM 5839 O O . GLY B 1 231 ? -29.834 -3.947 -37.215 1.00 43.23 ? 231 GLY B O 1 ATOM 5840 N N . GLU B 1 232 ? -29.301 -5.313 -38.929 1.00 43.58 ? 232 GLU B N 1 ATOM 5841 C CA . GLU B 1 232 ? -29.570 -6.572 -38.221 1.00 43.70 ? 232 GLU B CA 1 ATOM 5842 C C . GLU B 1 232 ? -28.613 -6.779 -37.033 1.00 43.26 ? 232 GLU B C 1 ATOM 5843 O O . GLU B 1 232 ? -27.434 -6.428 -37.105 1.00 43.07 ? 232 GLU B O 1 ATOM 5844 C CB . GLU B 1 232 ? -29.536 -7.763 -39.202 1.00 43.97 ? 232 GLU B CB 1 ATOM 5845 C CG . GLU B 1 232 ? -28.613 -8.931 -38.793 1.00 46.19 ? 232 GLU B CG 1 ATOM 5846 C CD . GLU B 1 232 ? -28.986 -10.288 -39.409 1.00 49.00 ? 232 GLU B CD 1 ATOM 5847 O OE1 . GLU B 1 232 ? -28.913 -10.444 -40.653 1.00 49.64 ? 232 GLU B OE1 1 ATOM 5848 O OE2 . GLU B 1 232 ? -29.328 -11.214 -38.636 1.00 49.63 ? 232 GLU B OE2 1 ATOM 5849 N N . HIS B 1 233 ? -29.147 -7.331 -35.944 1.00 42.88 ? 233 HIS B N 1 ATOM 5850 C CA . HIS B 1 233 ? -28.378 -7.632 -34.738 1.00 42.56 ? 233 HIS B CA 1 ATOM 5851 C C . HIS B 1 233 ? -28.267 -9.144 -34.585 1.00 41.33 ? 233 HIS B C 1 ATOM 5852 O O . HIS B 1 233 ? -29.230 -9.867 -34.823 1.00 41.13 ? 233 HIS B O 1 ATOM 5853 C CB . HIS B 1 233 ? -29.065 -7.036 -33.495 1.00 43.30 ? 233 HIS B CB 1 ATOM 5854 C CG . HIS B 1 233 ? -28.959 -5.542 -33.387 1.00 46.75 ? 233 HIS B CG 1 ATOM 5855 N ND1 . HIS B 1 233 ? -29.014 -4.879 -32.177 1.00 49.89 ? 233 HIS B ND1 1 ATOM 5856 C CD2 . HIS B 1 233 ? -28.795 -4.581 -34.331 1.00 49.50 ? 233 HIS B CD2 1 ATOM 5857 C CE1 . HIS B 1 233 ? -28.890 -3.578 -32.381 1.00 50.56 ? 233 HIS B CE1 1 ATOM 5858 N NE2 . HIS B 1 233 ? -28.759 -3.370 -33.680 1.00 50.55 ? 233 HIS B NE2 1 ATOM 5859 N N . HIS B 1 234 ? -27.090 -9.620 -34.196 1.00 40.12 ? 234 HIS B N 1 ATOM 5860 C CA . HIS B 1 234 ? -26.909 -11.031 -33.876 1.00 39.03 ? 234 HIS B CA 1 ATOM 5861 C C . HIS B 1 234 ? -27.120 -11.261 -32.376 1.00 38.20 ? 234 HIS B C 1 ATOM 5862 O O . HIS B 1 234 ? -27.187 -10.308 -31.611 1.00 38.04 ? 234 HIS B O 1 ATOM 5863 C CB . HIS B 1 234 ? -25.523 -11.500 -34.305 1.00 38.92 ? 234 HIS B CB 1 ATOM 5864 C CG . HIS B 1 234 ? -25.297 -11.466 -35.784 1.00 39.51 ? 234 HIS B CG 1 ATOM 5865 N ND1 . HIS B 1 234 ? -25.913 -12.339 -36.657 1.00 40.29 ? 234 HIS B ND1 1 ATOM 5866 C CD2 . HIS B 1 234 ? -24.492 -10.684 -36.543 1.00 39.99 ? 234 HIS B CD2 1 ATOM 5867 C CE1 . HIS B 1 234 ? -25.513 -12.083 -37.890 1.00 40.09 ? 234 HIS B CE1 1 ATOM 5868 N NE2 . HIS B 1 234 ? -24.651 -11.083 -37.849 1.00 40.03 ? 234 HIS B NE2 1 ATOM 5869 N N . ASP B 1 235 ? -27.224 -12.519 -31.960 1.00 37.53 ? 235 ASP B N 1 ATOM 5870 C CA . ASP B 1 235 ? -27.435 -12.836 -30.551 1.00 37.08 ? 235 ASP B CA 1 ATOM 5871 C C . ASP B 1 235 ? -26.198 -13.437 -29.865 1.00 37.04 ? 235 ASP B C 1 ATOM 5872 O O . ASP B 1 235 ? -25.127 -13.549 -30.475 1.00 36.94 ? 235 ASP B O 1 ATOM 5873 C CB . ASP B 1 235 ? -28.683 -13.717 -30.371 1.00 36.91 ? 235 ASP B CB 1 ATOM 5874 C CG . ASP B 1 235 ? -28.534 -15.108 -30.975 1.00 37.00 ? 235 ASP B CG 1 ATOM 5875 O OD1 . ASP B 1 235 ? -27.421 -15.495 -31.407 1.00 36.83 ? 235 ASP B OD1 1 ATOM 5876 O OD2 . ASP B 1 235 ? -29.554 -15.833 -31.008 1.00 37.67 ? 235 ASP B OD2 1 ATOM 5877 N N . GLU B 1 236 ? -26.357 -13.811 -28.595 1.00 37.04 ? 236 GLU B N 1 ATOM 5878 C CA . GLU B 1 236 ? -25.280 -14.402 -27.790 1.00 37.32 ? 236 GLU B CA 1 ATOM 5879 C C . GLU B 1 236 ? -24.687 -15.668 -28.415 1.00 37.31 ? 236 GLU B C 1 ATOM 5880 O O . GLU B 1 236 ? -23.466 -15.783 -28.517 1.00 37.25 ? 236 GLU B O 1 ATOM 5881 C CB . GLU B 1 236 ? -25.754 -14.680 -26.356 1.00 37.38 ? 236 GLU B CB 1 ATOM 5882 C CG . GLU B 1 236 ? -26.083 -13.430 -25.535 1.00 38.46 ? 236 GLU B CG 1 ATOM 5883 C CD . GLU B 1 236 ? -27.482 -12.861 -25.794 1.00 40.06 ? 236 GLU B CD 1 ATOM 5884 O OE1 . GLU B 1 236 ? -28.315 -13.496 -26.480 1.00 40.24 ? 236 GLU B OE1 1 ATOM 5885 O OE2 . GLU B 1 236 ? -27.751 -11.755 -25.289 1.00 41.72 ? 236 GLU B OE2 1 ATOM 5886 N N . GLU B 1 237 ? -25.552 -16.600 -28.826 1.00 37.46 ? 237 GLU B N 1 ATOM 5887 C CA . GLU B 1 237 ? -25.135 -17.806 -29.548 1.00 37.79 ? 237 GLU B CA 1 ATOM 5888 C C . GLU B 1 237 ? -24.184 -17.476 -30.704 1.00 36.57 ? 237 GLU B C 1 ATOM 5889 O O . GLU B 1 237 ? -23.106 -18.070 -30.830 1.00 36.52 ? 237 GLU B O 1 ATOM 5890 C CB . GLU B 1 237 ? -26.343 -18.578 -30.092 1.00 38.50 ? 237 GLU B CB 1 ATOM 5891 C CG . GLU B 1 237 ? -26.917 -19.651 -29.158 1.00 43.42 ? 237 GLU B CG 1 ATOM 5892 C CD . GLU B 1 237 ? -28.165 -19.192 -28.400 1.00 50.17 ? 237 GLU B CD 1 ATOM 5893 O OE1 . GLU B 1 237 ? -28.737 -18.133 -28.758 1.00 52.91 ? 237 GLU B OE1 1 ATOM 5894 O OE2 . GLU B 1 237 ? -28.579 -19.895 -27.447 1.00 52.57 ? 237 GLU B OE2 1 ATOM 5895 N N . TRP B 1 238 ? -24.592 -16.517 -31.532 1.00 35.22 ? 238 TRP B N 1 ATOM 5896 C CA . TRP B 1 238 ? -23.822 -16.095 -32.701 1.00 33.80 ? 238 TRP B CA 1 ATOM 5897 C C . TRP B 1 238 ? -22.413 -15.572 -32.342 1.00 33.14 ? 238 TRP B C 1 ATOM 5898 O O . TRP B 1 238 ? -21.444 -15.858 -33.057 1.00 32.90 ? 238 TRP B O 1 ATOM 5899 C CB . TRP B 1 238 ? -24.612 -15.052 -33.490 1.00 33.65 ? 238 TRP B CB 1 ATOM 5900 C CG . TRP B 1 238 ? -24.012 -14.711 -34.816 1.00 33.12 ? 238 TRP B CG 1 ATOM 5901 C CD1 . TRP B 1 238 ? -24.369 -15.221 -36.028 1.00 32.30 ? 238 TRP B CD1 1 ATOM 5902 C CD2 . TRP B 1 238 ? -22.953 -13.779 -35.067 1.00 32.76 ? 238 TRP B CD2 1 ATOM 5903 N NE1 . TRP B 1 238 ? -23.598 -14.673 -37.017 1.00 32.31 ? 238 TRP B NE1 1 ATOM 5904 C CE2 . TRP B 1 238 ? -22.720 -13.783 -36.458 1.00 32.70 ? 238 TRP B CE2 1 ATOM 5905 C CE3 . TRP B 1 238 ? -22.176 -12.941 -34.251 1.00 32.65 ? 238 TRP B CE3 1 ATOM 5906 C CZ2 . TRP B 1 238 ? -21.738 -12.980 -37.060 1.00 32.46 ? 238 TRP B CZ2 1 ATOM 5907 C CZ3 . TRP B 1 238 ? -21.198 -12.137 -34.851 1.00 32.37 ? 238 TRP B CZ3 1 ATOM 5908 C CH2 . TRP B 1 238 ? -20.995 -12.163 -36.245 1.00 32.21 ? 238 TRP B CH2 1 ATOM 5909 N N . SER B 1 239 ? -22.308 -14.810 -31.250 1.00 31.87 ? 239 SER B N 1 ATOM 5910 C CA . SER B 1 239 ? -21.012 -14.323 -30.767 1.00 30.94 ? 239 SER B CA 1 ATOM 5911 C C . SER B 1 239 ? -20.100 -15.450 -30.276 1.00 30.59 ? 239 SER B C 1 ATOM 5912 O O . SER B 1 239 ? -18.901 -15.445 -30.556 1.00 30.31 ? 239 SER B O 1 ATOM 5913 C CB . SER B 1 239 ? -21.185 -13.274 -29.663 1.00 30.87 ? 239 SER B CB 1 ATOM 5914 O OG . SER B 1 239 ? -21.512 -12.005 -30.195 1.00 29.77 ? 239 SER B OG 1 ATOM 5915 N N . VAL B 1 240 ? -20.665 -16.408 -29.549 1.00 30.42 ? 240 VAL B N 1 ATOM 5916 C CA . VAL B 1 240 ? -19.902 -17.557 -29.068 1.00 30.52 ? 240 VAL B CA 1 ATOM 5917 C C . VAL B 1 240 ? -19.441 -18.426 -30.238 1.00 30.86 ? 240 VAL B C 1 ATOM 5918 O O . VAL B 1 240 ? -18.307 -18.915 -30.239 1.00 30.97 ? 240 VAL B O 1 ATOM 5919 C CB . VAL B 1 240 ? -20.699 -18.392 -28.041 1.00 30.52 ? 240 VAL B CB 1 ATOM 5920 C CG1 . VAL B 1 240 ? -19.896 -19.618 -27.591 1.00 30.04 ? 240 VAL B CG1 1 ATOM 5921 C CG2 . VAL B 1 240 ? -21.088 -17.529 -26.834 1.00 30.17 ? 240 VAL B CG2 1 ATOM 5922 N N . LYS B 1 241 ? -20.313 -18.596 -31.236 1.00 31.32 ? 241 LYS B N 1 ATOM 5923 C CA . LYS B 1 241 ? -19.982 -19.331 -32.458 1.00 31.81 ? 241 LYS B CA 1 ATOM 5924 C C . LYS B 1 241 ? -18.800 -18.665 -33.175 1.00 31.45 ? 241 LYS B C 1 ATOM 5925 O O . LYS B 1 241 ? -17.843 -19.333 -33.582 1.00 31.16 ? 241 LYS B O 1 ATOM 5926 C CB . LYS B 1 241 ? -21.201 -19.393 -33.384 1.00 32.39 ? 241 LYS B CB 1 ATOM 5927 C CG . LYS B 1 241 ? -21.069 -20.371 -34.570 1.00 35.11 ? 241 LYS B CG 1 ATOM 5928 C CD . LYS B 1 241 ? -21.874 -21.654 -34.347 1.00 40.19 ? 241 LYS B CD 1 ATOM 5929 C CE . LYS B 1 241 ? -23.393 -21.396 -34.446 1.00 42.44 ? 241 LYS B CE 1 ATOM 5930 N NZ . LYS B 1 241 ? -24.219 -22.459 -33.785 1.00 44.04 ? 241 LYS B NZ 1 ATOM 5931 N N . THR B 1 242 ? -18.881 -17.343 -33.311 1.00 31.32 ? 242 THR B N 1 ATOM 5932 C CA . THR B 1 242 ? -17.834 -16.542 -33.935 1.00 31.32 ? 242 THR B CA 1 ATOM 5933 C C . THR B 1 242 ? -16.483 -16.622 -33.182 1.00 31.97 ? 242 THR B C 1 ATOM 5934 O O . THR B 1 242 ? -15.431 -16.797 -33.805 1.00 32.11 ? 242 THR B O 1 ATOM 5935 C CB . THR B 1 242 ? -18.302 -15.094 -34.081 1.00 31.19 ? 242 THR B CB 1 ATOM 5936 O OG1 . THR B 1 242 ? -19.515 -15.064 -34.843 1.00 30.46 ? 242 THR B OG1 1 ATOM 5937 C CG2 . THR B 1 242 ? -17.251 -14.227 -34.771 1.00 30.96 ? 242 THR B CG2 1 ATOM 5938 N N . TYR B 1 243 ? -16.509 -16.512 -31.854 1.00 32.26 ? 243 TYR B N 1 ATOM 5939 C CA . TYR B 1 243 ? -15.285 -16.643 -31.068 1.00 32.85 ? 243 TYR B CA 1 ATOM 5940 C C . TYR B 1 243 ? -14.624 -17.979 -31.372 1.00 33.36 ? 243 TYR B C 1 ATOM 5941 O O . TYR B 1 243 ? -13.437 -18.026 -31.691 1.00 33.42 ? 243 TYR B O 1 ATOM 5942 C CB . TYR B 1 243 ? -15.554 -16.530 -29.562 1.00 32.63 ? 243 TYR B CB 1 ATOM 5943 C CG . TYR B 1 243 ? -15.606 -15.128 -28.993 1.00 32.46 ? 243 TYR B CG 1 ATOM 5944 C CD1 . TYR B 1 243 ? -14.459 -14.332 -28.913 1.00 32.55 ? 243 TYR B CD1 1 ATOM 5945 C CD2 . TYR B 1 243 ? -16.801 -14.607 -28.488 1.00 32.31 ? 243 TYR B CD2 1 ATOM 5946 C CE1 . TYR B 1 243 ? -14.513 -13.035 -28.362 1.00 31.79 ? 243 TYR B CE1 1 ATOM 5947 C CE2 . TYR B 1 243 ? -16.866 -13.324 -27.942 1.00 31.11 ? 243 TYR B CE2 1 ATOM 5948 C CZ . TYR B 1 243 ? -15.723 -12.545 -27.881 1.00 31.24 ? 243 TYR B CZ 1 ATOM 5949 O OH . TYR B 1 243 ? -15.800 -11.284 -27.334 1.00 30.31 ? 243 TYR B OH 1 ATOM 5950 N N . GLN B 1 244 ? -15.406 -19.054 -31.277 1.00 34.12 ? 244 GLN B N 1 ATOM 5951 C CA . GLN B 1 244 ? -14.935 -20.399 -31.603 1.00 35.17 ? 244 GLN B CA 1 ATOM 5952 C C . GLN B 1 244 ? -14.315 -20.441 -33.007 1.00 35.41 ? 244 GLN B C 1 ATOM 5953 O O . GLN B 1 244 ? -13.195 -20.938 -33.182 1.00 35.51 ? 244 GLN B O 1 ATOM 5954 C CB . GLN B 1 244 ? -16.081 -21.418 -31.477 1.00 35.37 ? 244 GLN B CB 1 ATOM 5955 C CG . GLN B 1 244 ? -15.705 -22.876 -31.799 1.00 36.81 ? 244 GLN B CG 1 ATOM 5956 C CD . GLN B 1 244 ? -16.822 -23.869 -31.479 1.00 39.14 ? 244 GLN B CD 1 ATOM 5957 O OE1 . GLN B 1 244 ? -17.996 -23.618 -31.763 1.00 40.76 ? 244 GLN B OE1 1 ATOM 5958 N NE2 . GLN B 1 244 ? -16.458 -25.005 -30.887 1.00 39.82 ? 244 GLN B NE2 1 ATOM 5959 N N . GLU B 1 245 ? -15.042 -19.891 -33.985 1.00 35.69 ? 245 GLU B N 1 ATOM 5960 C CA . GLU B 1 245 ? -14.649 -19.948 -35.392 1.00 36.03 ? 245 GLU B CA 1 ATOM 5961 C C . GLU B 1 245 ? -13.377 -19.182 -35.691 1.00 35.58 ? 245 GLU B C 1 ATOM 5962 O O . GLU B 1 245 ? -12.498 -19.683 -36.393 1.00 35.60 ? 245 GLU B O 1 ATOM 5963 C CB . GLU B 1 245 ? -15.772 -19.454 -36.295 1.00 36.42 ? 245 GLU B CB 1 ATOM 5964 C CG . GLU B 1 245 ? -16.845 -20.499 -36.575 1.00 39.23 ? 245 GLU B CG 1 ATOM 5965 C CD . GLU B 1 245 ? -17.989 -19.955 -37.416 1.00 43.10 ? 245 GLU B CD 1 ATOM 5966 O OE1 . GLU B 1 245 ? -17.801 -18.907 -38.080 1.00 44.11 ? 245 GLU B OE1 1 ATOM 5967 O OE2 . GLU B 1 245 ? -19.075 -20.580 -37.416 1.00 45.05 ? 245 GLU B OE2 1 ATOM 5968 N N . VAL B 1 246 ? -13.279 -17.965 -35.166 1.00 35.18 ? 246 VAL B N 1 ATOM 5969 C CA . VAL B 1 246 ? -12.078 -17.156 -35.362 1.00 34.66 ? 246 VAL B CA 1 ATOM 5970 C C . VAL B 1 246 ? -10.861 -17.815 -34.677 1.00 34.62 ? 246 VAL B C 1 ATOM 5971 O O . VAL B 1 246 ? -9.762 -17.833 -35.238 1.00 34.17 ? 246 VAL B O 1 ATOM 5972 C CB . VAL B 1 246 ? -12.283 -15.687 -34.907 1.00 34.57 ? 246 VAL B CB 1 ATOM 5973 C CG1 . VAL B 1 246 ? -11.054 -14.852 -35.216 1.00 34.28 ? 246 VAL B CG1 1 ATOM 5974 C CG2 . VAL B 1 246 ? -13.499 -15.070 -35.597 1.00 34.35 ? 246 VAL B CG2 1 ATOM 5975 N N . ALA B 1 247 ? -11.077 -18.384 -33.488 1.00 34.77 ? 247 ALA B N 1 ATOM 5976 C CA . ALA B 1 247 ? -10.013 -19.076 -32.752 1.00 35.13 ? 247 ALA B CA 1 ATOM 5977 C C . ALA B 1 247 ? -9.520 -20.312 -33.500 1.00 35.38 ? 247 ALA B C 1 ATOM 5978 O O . ALA B 1 247 ? -8.318 -20.579 -33.528 1.00 35.53 ? 247 ALA B O 1 ATOM 5979 C CB . ALA B 1 247 ? -10.462 -19.436 -31.341 1.00 34.85 ? 247 ALA B CB 1 ATOM 5980 N N . GLN B 1 248 ? -10.446 -21.055 -34.110 1.00 35.62 ? 248 GLN B N 1 ATOM 5981 C CA . GLN B 1 248 ? -10.086 -22.191 -34.969 1.00 36.12 ? 248 GLN B CA 1 ATOM 5982 C C . GLN B 1 248 ? -9.251 -21.742 -36.165 1.00 35.93 ? 248 GLN B C 1 ATOM 5983 O O . GLN B 1 248 ? -8.221 -22.343 -36.463 1.00 36.10 ? 248 GLN B O 1 ATOM 5984 C CB . GLN B 1 248 ? -11.330 -22.959 -35.432 1.00 36.22 ? 248 GLN B CB 1 ATOM 5985 C CG . GLN B 1 248 ? -11.740 -24.098 -34.494 1.00 38.03 ? 248 GLN B CG 1 ATOM 5986 C CD . GLN B 1 248 ? -13.257 -24.330 -34.432 1.00 41.18 ? 248 GLN B CD 1 ATOM 5987 O OE1 . GLN B 1 248 ? -14.012 -23.893 -35.311 1.00 42.53 ? 248 GLN B OE1 1 ATOM 5988 N NE2 . GLN B 1 248 ? -13.706 -25.025 -33.384 1.00 41.88 ? 248 GLN B NE2 1 ATOM 5989 N N . LYS B 1 249 ? -9.689 -20.676 -36.827 1.00 35.82 ? 249 LYS B N 1 ATOM 5990 C CA . LYS B 1 249 ? -8.944 -20.079 -37.934 1.00 36.16 ? 249 LYS B CA 1 ATOM 5991 C C . LYS B 1 249 ? -7.533 -19.652 -37.511 1.00 35.76 ? 249 LYS B C 1 ATOM 5992 O O . LYS B 1 249 ? -6.565 -19.868 -38.248 1.00 36.09 ? 249 LYS B O 1 ATOM 5993 C CB . LYS B 1 249 ? -9.726 -18.895 -38.525 1.00 36.63 ? 249 LYS B CB 1 ATOM 5994 C CG . LYS B 1 249 ? -8.974 -18.056 -39.564 1.00 39.15 ? 249 LYS B CG 1 ATOM 5995 C CD . LYS B 1 249 ? -8.810 -18.776 -40.895 1.00 43.60 ? 249 LYS B CD 1 ATOM 5996 C CE . LYS B 1 249 ? -9.536 -18.039 -42.022 1.00 45.84 ? 249 LYS B CE 1 ATOM 5997 N NZ . LYS B 1 249 ? -9.071 -18.476 -43.383 1.00 47.53 ? 249 LYS B NZ 1 ATOM 5998 N N . PHE B 1 250 ? -7.419 -19.060 -36.323 1.00 35.06 ? 250 PHE B N 1 ATOM 5999 C CA . PHE B 1 250 ? -6.124 -18.641 -35.800 1.00 34.26 ? 250 PHE B CA 1 ATOM 6000 C C . PHE B 1 250 ? -5.214 -19.830 -35.478 1.00 34.83 ? 250 PHE B C 1 ATOM 6001 O O . PHE B 1 250 ? -4.026 -19.797 -35.797 1.00 34.60 ? 250 PHE B O 1 ATOM 6002 C CB . PHE B 1 250 ? -6.283 -17.738 -34.567 1.00 33.41 ? 250 PHE B CB 1 ATOM 6003 C CG . PHE B 1 250 ? -4.985 -17.128 -34.093 1.00 30.98 ? 250 PHE B CG 1 ATOM 6004 C CD1 . PHE B 1 250 ? -4.514 -15.944 -34.655 1.00 28.67 ? 250 PHE B CD1 1 ATOM 6005 C CD2 . PHE B 1 250 ? -4.226 -17.744 -33.099 1.00 28.67 ? 250 PHE B CD2 1 ATOM 6006 C CE1 . PHE B 1 250 ? -3.309 -15.380 -34.232 1.00 27.73 ? 250 PHE B CE1 1 ATOM 6007 C CE2 . PHE B 1 250 ? -3.017 -17.190 -32.670 1.00 27.16 ? 250 PHE B CE2 1 ATOM 6008 C CZ . PHE B 1 250 ? -2.558 -16.006 -33.236 1.00 26.68 ? 250 PHE B CZ 1 ATOM 6009 N N . VAL B 1 251 ? -5.771 -20.868 -34.849 1.00 35.52 ? 251 VAL B N 1 ATOM 6010 C CA . VAL B 1 251 ? -4.996 -22.047 -34.460 1.00 36.65 ? 251 VAL B CA 1 ATOM 6011 C C . VAL B 1 251 ? -4.508 -22.834 -35.686 1.00 37.83 ? 251 VAL B C 1 ATOM 6012 O O . VAL B 1 251 ? -3.493 -23.540 -35.627 1.00 37.99 ? 251 VAL B O 1 ATOM 6013 C CB . VAL B 1 251 ? -5.784 -22.945 -33.467 1.00 36.58 ? 251 VAL B CB 1 ATOM 6014 C CG1 . VAL B 1 251 ? -5.145 -24.329 -33.318 1.00 35.74 ? 251 VAL B CG1 1 ATOM 6015 C CG2 . VAL B 1 251 ? -5.878 -22.261 -32.095 1.00 36.41 ? 251 VAL B CG2 1 ATOM 6016 N N . GLU B 1 252 ? -5.224 -22.681 -36.800 1.00 39.24 ? 252 GLU B N 1 ATOM 6017 C CA . GLU B 1 252 ? -4.860 -23.317 -38.060 1.00 40.59 ? 252 GLU B CA 1 ATOM 6018 C C . GLU B 1 252 ? -3.571 -22.765 -38.649 1.00 40.87 ? 252 GLU B C 1 ATOM 6019 O O . GLU B 1 252 ? -2.815 -23.506 -39.278 1.00 41.01 ? 252 GLU B O 1 ATOM 6020 C CB . GLU B 1 252 ? -5.998 -23.205 -39.072 1.00 40.96 ? 252 GLU B CB 1 ATOM 6021 C CG . GLU B 1 252 ? -6.958 -24.384 -39.024 1.00 43.55 ? 252 GLU B CG 1 ATOM 6022 C CD . GLU B 1 252 ? -8.326 -24.076 -39.627 1.00 47.54 ? 252 GLU B CD 1 ATOM 6023 O OE1 . GLU B 1 252 ? -8.429 -23.187 -40.512 1.00 48.37 ? 252 GLU B OE1 1 ATOM 6024 O OE2 . GLU B 1 252 ? -9.303 -24.739 -39.207 1.00 48.87 ? 252 GLU B OE2 1 ATOM 6025 N N . THR B 1 253 ? -3.321 -21.473 -38.443 1.00 41.23 ? 253 THR B N 1 ATOM 6026 C CA . THR B 1 253 ? -2.100 -20.841 -38.944 1.00 41.62 ? 253 THR B CA 1 ATOM 6027 C C . THR B 1 253 ? -1.076 -20.577 -37.839 1.00 41.55 ? 253 THR B C 1 ATOM 6028 O O . THR B 1 253 ? -0.024 -19.977 -38.085 1.00 41.76 ? 253 THR B O 1 ATOM 6029 C CB . THR B 1 253 ? -2.404 -19.545 -39.719 1.00 41.80 ? 253 THR B CB 1 ATOM 6030 O OG1 . THR B 1 253 ? -3.100 -18.625 -38.869 1.00 42.76 ? 253 THR B OG1 1 ATOM 6031 C CG2 . THR B 1 253 ? -3.262 -19.851 -40.950 1.00 42.00 ? 253 THR B CG2 1 ATOM 6032 N N . HIS B 1 254 ? -1.396 -21.030 -36.629 1.00 41.37 ? 254 HIS B N 1 ATOM 6033 C CA . HIS B 1 254 ? -0.495 -20.961 -35.479 1.00 40.95 ? 254 HIS B CA 1 ATOM 6034 C C . HIS B 1 254 ? -0.736 -22.220 -34.632 1.00 41.33 ? 254 HIS B C 1 ATOM 6035 O O . HIS B 1 254 ? -1.422 -22.161 -33.605 1.00 41.25 ? 254 HIS B O 1 ATOM 6036 C CB . HIS B 1 254 ? -0.758 -19.706 -34.640 1.00 40.47 ? 254 HIS B CB 1 ATOM 6037 C CG . HIS B 1 254 ? -0.731 -18.426 -35.419 1.00 38.95 ? 254 HIS B CG 1 ATOM 6038 N ND1 . HIS B 1 254 ? -1.829 -17.949 -36.104 1.00 37.73 ? 254 HIS B ND1 1 ATOM 6039 C CD2 . HIS B 1 254 ? 0.250 -17.510 -35.598 1.00 37.77 ? 254 HIS B CD2 1 ATOM 6040 C CE1 . HIS B 1 254 ? -1.521 -16.801 -36.685 1.00 36.79 ? 254 HIS B CE1 1 ATOM 6041 N NE2 . HIS B 1 254 ? -0.265 -16.513 -36.393 1.00 37.29 ? 254 HIS B NE2 1 ATOM 6042 N N . PRO B 1 255 ? -0.168 -23.363 -35.059 1.00 41.44 ? 255 PRO B N 1 ATOM 6043 C CA . PRO B 1 255 ? -0.465 -24.681 -34.480 1.00 41.34 ? 255 PRO B CA 1 ATOM 6044 C C . PRO B 1 255 ? -0.104 -24.845 -32.993 1.00 41.20 ? 255 PRO B C 1 ATOM 6045 O O . PRO B 1 255 ? -0.589 -25.781 -32.343 1.00 41.20 ? 255 PRO B O 1 ATOM 6046 C CB . PRO B 1 255 ? 0.372 -25.636 -35.336 1.00 41.40 ? 255 PRO B CB 1 ATOM 6047 C CG . PRO B 1 255 ? 1.498 -24.800 -35.831 1.00 41.66 ? 255 PRO B CG 1 ATOM 6048 C CD . PRO B 1 255 ? 0.904 -23.439 -36.068 1.00 41.53 ? 255 PRO B CD 1 ATOM 6049 N N . GLU B 1 256 ? 0.730 -23.953 -32.460 1.00 40.75 ? 256 GLU B N 1 ATOM 6050 C CA . GLU B 1 256 ? 1.094 -23.991 -31.034 1.00 40.27 ? 256 GLU B CA 1 ATOM 6051 C C . GLU B 1 256 ? 0.107 -23.260 -30.109 1.00 39.22 ? 256 GLU B C 1 ATOM 6052 O O . GLU B 1 256 ? 0.054 -23.539 -28.912 1.00 39.22 ? 256 GLU B O 1 ATOM 6053 C CB . GLU B 1 256 ? 2.503 -23.449 -30.823 1.00 40.68 ? 256 GLU B CB 1 ATOM 6054 C CG . GLU B 1 256 ? 3.596 -24.413 -31.228 1.00 42.71 ? 256 GLU B CG 1 ATOM 6055 C CD . GLU B 1 256 ? 4.976 -23.825 -31.043 1.00 46.21 ? 256 GLU B CD 1 ATOM 6056 O OE1 . GLU B 1 256 ? 5.957 -24.566 -31.191 1.00 49.07 ? 256 GLU B OE1 1 ATOM 6057 O OE2 . GLU B 1 256 ? 5.095 -22.625 -30.743 1.00 47.79 ? 256 GLU B OE2 1 ATOM 6058 N N . PHE B 1 257 ? -0.663 -22.329 -30.666 1.00 37.86 ? 257 PHE B N 1 ATOM 6059 C CA . PHE B 1 257 ? -1.701 -21.632 -29.919 1.00 36.57 ? 257 PHE B CA 1 ATOM 6060 C C . PHE B 1 257 ? -2.844 -22.587 -29.551 1.00 36.15 ? 257 PHE B C 1 ATOM 6061 O O . PHE B 1 257 ? -3.395 -23.263 -30.418 1.00 36.32 ? 257 PHE B O 1 ATOM 6062 C CB . PHE B 1 257 ? -2.228 -20.458 -30.739 1.00 36.19 ? 257 PHE B CB 1 ATOM 6063 C CG . PHE B 1 257 ? -2.980 -19.451 -29.932 1.00 35.21 ? 257 PHE B CG 1 ATOM 6064 C CD1 . PHE B 1 257 ? -2.297 -18.489 -29.187 1.00 34.05 ? 257 PHE B CD1 1 ATOM 6065 C CD2 . PHE B 1 257 ? -4.375 -19.458 -29.913 1.00 34.33 ? 257 PHE B CD2 1 ATOM 6066 C CE1 . PHE B 1 257 ? -2.990 -17.553 -28.437 1.00 32.72 ? 257 PHE B CE1 1 ATOM 6067 C CE2 . PHE B 1 257 ? -5.071 -18.528 -29.168 1.00 33.65 ? 257 PHE B CE2 1 ATOM 6068 C CZ . PHE B 1 257 ? -4.375 -17.574 -28.427 1.00 32.96 ? 257 PHE B CZ 1 ATOM 6069 N N . ILE B 1 258 ? -3.190 -22.636 -28.265 1.00 35.57 ? 258 ILE B N 1 ATOM 6070 C CA . ILE B 1 258 ? -4.193 -23.575 -27.737 1.00 34.89 ? 258 ILE B CA 1 ATOM 6071 C C . ILE B 1 258 ? -5.632 -23.164 -28.077 1.00 34.94 ? 258 ILE B C 1 ATOM 6072 O O . ILE B 1 258 ? -6.462 -24.016 -28.375 1.00 35.31 ? 258 ILE B O 1 ATOM 6073 C CB . ILE B 1 258 ? -4.059 -23.762 -26.196 1.00 34.78 ? 258 ILE B CB 1 ATOM 6074 C CG1 . ILE B 1 258 ? -2.592 -23.971 -25.773 1.00 34.61 ? 258 ILE B CG1 1 ATOM 6075 C CG2 . ILE B 1 258 ? -4.975 -24.876 -25.683 1.00 33.70 ? 258 ILE B CG2 1 ATOM 6076 C CD1 . ILE B 1 258 ? -1.914 -25.205 -26.354 1.00 33.99 ? 258 ILE B CD1 1 ATOM 6077 N N . GLY B 1 259 ? -5.925 -21.866 -28.036 1.00 34.64 ? 259 GLY B N 1 ATOM 6078 C CA . GLY B 1 259 ? -7.266 -21.370 -28.340 1.00 34.18 ? 259 GLY B CA 1 ATOM 6079 C C . GLY B 1 259 ? -7.788 -20.380 -27.307 1.00 33.98 ? 259 GLY B C 1 ATOM 6080 O O . GLY B 1 259 ? -7.034 -19.865 -26.481 1.00 34.14 ? 259 GLY B O 1 ATOM 6081 N N . ILE B 1 260 ? -9.082 -20.093 -27.368 1.00 33.45 ? 260 ILE B N 1 ATOM 6082 C CA . ILE B 1 260 ? -9.711 -19.235 -26.379 1.00 33.05 ? 260 ILE B CA 1 ATOM 6083 C C . ILE B 1 260 ? -10.962 -19.879 -25.795 1.00 32.70 ? 260 ILE B C 1 ATOM 6084 O O . ILE B 1 260 ? -11.640 -20.668 -26.460 1.00 32.76 ? 260 ILE B O 1 ATOM 6085 C CB . ILE B 1 260 ? -10.083 -17.835 -26.948 1.00 33.32 ? 260 ILE B CB 1 ATOM 6086 C CG1 . ILE B 1 260 ? -11.244 -17.937 -27.940 1.00 33.71 ? 260 ILE B CG1 1 ATOM 6087 C CG2 . ILE B 1 260 ? -8.868 -17.142 -27.573 1.00 32.93 ? 260 ILE B CG2 1 ATOM 6088 C CD1 . ILE B 1 260 ? -11.681 -16.614 -28.499 1.00 35.88 ? 260 ILE B CD1 1 ATOM 6089 N N . LYS B 1 261 ? -11.256 -19.545 -24.545 1.00 31.96 ? 261 LYS B N 1 ATOM 6090 C CA . LYS B 1 261 ? -12.555 -19.849 -23.957 1.00 31.10 ? 261 LYS B CA 1 ATOM 6091 C C . LYS B 1 261 ? -13.221 -18.554 -23.498 1.00 30.21 ? 261 LYS B C 1 ATOM 6092 O O . LYS B 1 261 ? -12.561 -17.527 -23.330 1.00 30.04 ? 261 LYS B O 1 ATOM 6093 C CB . LYS B 1 261 ? -12.434 -20.855 -22.808 1.00 31.18 ? 261 LYS B CB 1 ATOM 6094 C CG . LYS B 1 261 ? -12.179 -22.289 -23.251 1.00 32.39 ? 261 LYS B CG 1 ATOM 6095 C CD . LYS B 1 261 ? -12.926 -23.251 -22.349 1.00 35.73 ? 261 LYS B CD 1 ATOM 6096 C CE . LYS B 1 261 ? -12.120 -24.505 -22.018 1.00 37.57 ? 261 LYS B CE 1 ATOM 6097 N NZ . LYS B 1 261 ? -12.174 -25.530 -23.088 1.00 39.85 ? 261 LYS B NZ 1 ATOM 6098 N N . ILE B 1 262 ? -14.532 -18.613 -23.304 1.00 29.22 ? 262 ILE B N 1 ATOM 6099 C CA . ILE B 1 262 ? -15.322 -17.447 -22.940 1.00 28.00 ? 262 ILE B CA 1 ATOM 6100 C C . ILE B 1 262 ? -15.939 -17.620 -21.550 1.00 27.51 ? 262 ILE B C 1 ATOM 6101 O O . ILE B 1 262 ? -16.539 -18.662 -21.243 1.00 27.56 ? 262 ILE B O 1 ATOM 6102 C CB . ILE B 1 262 ? -16.422 -17.178 -24.010 1.00 28.03 ? 262 ILE B CB 1 ATOM 6103 C CG1 . ILE B 1 262 ? -15.790 -16.874 -25.385 1.00 27.79 ? 262 ILE B CG1 1 ATOM 6104 C CG2 . ILE B 1 262 ? -17.399 -16.073 -23.573 1.00 27.04 ? 262 ILE B CG2 1 ATOM 6105 C CD1 . ILE B 1 262 ? -14.833 -15.673 -25.425 1.00 26.53 ? 262 ILE B CD1 1 ATOM 6106 N N . ILE B 1 263 ? -15.753 -16.607 -20.705 1.00 26.49 ? 263 ILE B N 1 ATOM 6107 C CA . ILE B 1 263 ? -16.501 -16.482 -19.455 1.00 25.68 ? 263 ILE B CA 1 ATOM 6108 C C . ILE B 1 263 ? -17.537 -15.399 -19.680 1.00 25.70 ? 263 ILE B C 1 ATOM 6109 O O . ILE B 1 263 ? -17.191 -14.232 -19.855 1.00 25.63 ? 263 ILE B O 1 ATOM 6110 C CB . ILE B 1 263 ? -15.598 -16.102 -18.263 1.00 25.67 ? 263 ILE B CB 1 ATOM 6111 C CG1 . ILE B 1 263 ? -14.545 -17.194 -18.020 1.00 24.26 ? 263 ILE B CG1 1 ATOM 6112 C CG2 . ILE B 1 263 ? -16.447 -15.856 -16.994 1.00 24.84 ? 263 ILE B CG2 1 ATOM 6113 C CD1 . ILE B 1 263 ? -13.307 -16.708 -17.326 1.00 23.00 ? 263 ILE B CD1 1 ATOM 6114 N N . TYR B 1 264 ? -18.805 -15.798 -19.719 1.00 25.71 ? 264 TYR B N 1 ATOM 6115 C CA . TYR B 1 264 ? -19.900 -14.863 -19.944 1.00 25.65 ? 264 TYR B CA 1 ATOM 6116 C C . TYR B 1 264 ? -20.088 -13.949 -18.736 1.00 25.99 ? 264 TYR B C 1 ATOM 6117 O O . TYR B 1 264 ? -20.022 -14.399 -17.595 1.00 25.89 ? 264 TYR B O 1 ATOM 6118 C CB . TYR B 1 264 ? -21.182 -15.617 -20.279 1.00 25.45 ? 264 TYR B CB 1 ATOM 6119 C CG . TYR B 1 264 ? -22.405 -14.756 -20.481 1.00 25.02 ? 264 TYR B CG 1 ATOM 6120 C CD1 . TYR B 1 264 ? -22.374 -13.638 -21.320 1.00 25.17 ? 264 TYR B CD1 1 ATOM 6121 C CD2 . TYR B 1 264 ? -23.606 -15.074 -19.851 1.00 25.02 ? 264 TYR B CD2 1 ATOM 6122 C CE1 . TYR B 1 264 ? -23.512 -12.847 -21.509 1.00 25.30 ? 264 TYR B CE1 1 ATOM 6123 C CE2 . TYR B 1 264 ? -24.744 -14.291 -20.030 1.00 25.15 ? 264 TYR B CE2 1 ATOM 6124 C CZ . TYR B 1 264 ? -24.689 -13.187 -20.860 1.00 25.36 ? 264 TYR B CZ 1 ATOM 6125 O OH . TYR B 1 264 ? -25.805 -12.424 -21.041 1.00 25.95 ? 264 TYR B OH 1 ATOM 6126 N N . SER B 1 265 ? -20.311 -12.663 -18.998 1.00 26.43 ? 265 SER B N 1 ATOM 6127 C CA . SER B 1 265 ? -20.363 -11.667 -17.932 1.00 27.10 ? 265 SER B CA 1 ATOM 6128 C C . SER B 1 265 ? -21.430 -10.594 -18.112 1.00 27.53 ? 265 SER B C 1 ATOM 6129 O O . SER B 1 265 ? -21.846 -10.277 -19.231 1.00 27.33 ? 265 SER B O 1 ATOM 6130 C CB . SER B 1 265 ? -18.993 -11.014 -17.738 1.00 26.95 ? 265 SER B CB 1 ATOM 6131 O OG . SER B 1 265 ? -18.579 -10.339 -18.905 1.00 27.68 ? 265 SER B OG 1 ATOM 6132 N N . ASP B 1 266 ? -21.861 -10.042 -16.984 1.00 28.37 ? 266 ASP B N 1 ATOM 6133 C CA . ASP B 1 266 ? -22.839 -8.971 -16.964 1.00 29.41 ? 266 ASP B CA 1 ATOM 6134 C C . ASP B 1 266 ? -22.491 -8.003 -15.833 1.00 29.89 ? 266 ASP B C 1 ATOM 6135 O O . ASP B 1 266 ? -21.784 -8.366 -14.896 1.00 29.94 ? 266 ASP B O 1 ATOM 6136 C CB . ASP B 1 266 ? -24.251 -9.548 -16.802 1.00 29.18 ? 266 ASP B CB 1 ATOM 6137 C CG . ASP B 1 266 ? -25.335 -8.655 -17.404 1.00 30.38 ? 266 ASP B CG 1 ATOM 6138 O OD1 . ASP B 1 266 ? -25.078 -7.472 -17.741 1.00 30.62 ? 266 ASP B OD1 1 ATOM 6139 O OD2 . ASP B 1 266 ? -26.475 -9.149 -17.539 1.00 32.09 ? 266 ASP B OD2 1 ATOM 6140 N N . HIS B 1 267 ? -22.990 -6.775 -15.933 1.00 30.87 ? 267 HIS B N 1 ATOM 6141 C CA . HIS B 1 267 ? -22.647 -5.701 -15.002 1.00 31.86 ? 267 HIS B CA 1 ATOM 6142 C C . HIS B 1 267 ? -23.343 -5.822 -13.660 1.00 31.69 ? 267 HIS B C 1 ATOM 6143 O O . HIS B 1 267 ? -24.553 -6.050 -13.589 1.00 31.72 ? 267 HIS B O 1 ATOM 6144 C CB . HIS B 1 267 ? -22.982 -4.338 -15.610 1.00 32.50 ? 267 HIS B CB 1 ATOM 6145 C CG . HIS B 1 267 ? -21.957 -3.845 -16.574 1.00 35.00 ? 267 HIS B CG 1 ATOM 6146 N ND1 . HIS B 1 267 ? -22.164 -3.826 -17.935 1.00 37.53 ? 267 HIS B ND1 1 ATOM 6147 C CD2 . HIS B 1 267 ? -20.708 -3.360 -16.375 1.00 37.36 ? 267 HIS B CD2 1 ATOM 6148 C CE1 . HIS B 1 267 ? -21.090 -3.343 -18.535 1.00 38.14 ? 267 HIS B CE1 1 ATOM 6149 N NE2 . HIS B 1 267 ? -20.192 -3.053 -17.611 1.00 38.48 ? 267 HIS B NE2 1 ATOM 6150 N N . ARG B 1 268 ? -22.567 -5.618 -12.602 1.00 31.64 ? 268 ARG B N 1 ATOM 6151 C CA . ARG B 1 268 ? -23.048 -5.742 -11.229 1.00 31.50 ? 268 ARG B CA 1 ATOM 6152 C C . ARG B 1 268 ? -23.918 -4.561 -10.763 1.00 31.97 ? 268 ARG B C 1 ATOM 6153 O O . ARG B 1 268 ? -24.268 -4.476 -9.588 1.00 32.07 ? 268 ARG B O 1 ATOM 6154 C CB . ARG B 1 268 ? -21.860 -5.944 -10.284 1.00 31.20 ? 268 ARG B CB 1 ATOM 6155 C CG . ARG B 1 268 ? -20.904 -4.768 -10.218 1.00 29.80 ? 268 ARG B CG 1 ATOM 6156 C CD . ARG B 1 268 ? -19.617 -5.137 -9.522 1.00 28.73 ? 268 ARG B CD 1 ATOM 6157 N NE . ARG B 1 268 ? -19.869 -5.886 -8.294 1.00 28.31 ? 268 ARG B NE 1 ATOM 6158 C CZ . ARG B 1 268 ? -19.473 -7.135 -8.077 1.00 27.18 ? 268 ARG B CZ 1 ATOM 6159 N NH1 . ARG B 1 268 ? -18.765 -7.781 -8.994 1.00 28.98 ? 268 ARG B NH1 1 ATOM 6160 N NH2 . ARG B 1 268 ? -19.766 -7.734 -6.933 1.00 25.62 ? 268 ARG B NH2 1 ATOM 6161 N N . SER B 1 269 ? -24.260 -3.660 -11.677 1.00 32.47 ? 269 SER B N 1 ATOM 6162 C CA . SER B 1 269 ? -25.104 -2.517 -11.350 1.00 33.29 ? 269 SER B CA 1 ATOM 6163 C C . SER B 1 269 ? -26.576 -2.785 -11.687 1.00 33.93 ? 269 SER B C 1 ATOM 6164 O O . SER B 1 269 ? -27.423 -1.888 -11.615 1.00 34.17 ? 269 SER B O 1 ATOM 6165 C CB . SER B 1 269 ? -24.601 -1.262 -12.070 1.00 33.04 ? 269 SER B CB 1 ATOM 6166 O OG . SER B 1 269 ? -24.574 -1.458 -13.470 1.00 33.04 ? 269 SER B OG 1 ATOM 6167 N N . LYS B 1 270 ? -26.878 -4.031 -12.031 1.00 34.74 ? 270 LYS B N 1 ATOM 6168 C CA . LYS B 1 270 ? -28.200 -4.394 -12.522 1.00 35.38 ? 270 LYS B CA 1 ATOM 6169 C C . LYS B 1 270 ? -29.065 -5.124 -11.492 1.00 35.78 ? 270 LYS B C 1 ATOM 6170 O O . LYS B 1 270 ? -28.566 -5.681 -10.517 1.00 35.60 ? 270 LYS B O 1 ATOM 6171 C CB . LYS B 1 270 ? -28.067 -5.219 -13.799 1.00 35.45 ? 270 LYS B CB 1 ATOM 6172 C CG . LYS B 1 270 ? -27.578 -4.418 -14.995 1.00 35.98 ? 270 LYS B CG 1 ATOM 6173 C CD . LYS B 1 270 ? -27.459 -5.317 -16.206 1.00 37.47 ? 270 LYS B CD 1 ATOM 6174 C CE . LYS B 1 270 ? -27.068 -4.546 -17.453 1.00 37.43 ? 270 LYS B CE 1 ATOM 6175 N NZ . LYS B 1 270 ? -26.796 -5.500 -18.564 1.00 37.05 ? 270 LYS B NZ 1 ATOM 6176 N N . ASP B 1 271 ? -30.372 -5.104 -11.728 1.00 36.52 ? 271 ASP B N 1 ATOM 6177 C CA . ASP B 1 271 ? -31.345 -5.719 -10.838 1.00 37.32 ? 271 ASP B CA 1 ATOM 6178 C C . ASP B 1 271 ? -31.165 -7.225 -10.790 1.00 37.19 ? 271 ASP B C 1 ATOM 6179 O O . ASP B 1 271 ? -30.875 -7.859 -11.812 1.00 37.31 ? 271 ASP B O 1 ATOM 6180 C CB . ASP B 1 271 ? -32.767 -5.394 -11.300 1.00 37.86 ? 271 ASP B CB 1 ATOM 6181 C CG . ASP B 1 271 ? -33.082 -3.916 -11.219 1.00 39.97 ? 271 ASP B CG 1 ATOM 6182 O OD1 . ASP B 1 271 ? -32.768 -3.298 -10.178 1.00 42.62 ? 271 ASP B OD1 1 ATOM 6183 O OD2 . ASP B 1 271 ? -33.644 -3.367 -12.200 1.00 42.95 ? 271 ASP B OD2 1 ATOM 6184 N N . VAL B 1 272 ? -31.351 -7.794 -9.603 1.00 36.92 ? 272 VAL B N 1 ATOM 6185 C CA . VAL B 1 272 ? -31.240 -9.239 -9.418 1.00 36.74 ? 272 VAL B CA 1 ATOM 6186 C C . VAL B 1 272 ? -32.054 -10.020 -10.458 1.00 36.56 ? 272 VAL B C 1 ATOM 6187 O O . VAL B 1 272 ? -31.629 -11.087 -10.900 1.00 36.66 ? 272 VAL B O 1 ATOM 6188 C CB . VAL B 1 272 ? -31.545 -9.670 -7.943 1.00 36.77 ? 272 VAL B CB 1 ATOM 6189 C CG1 . VAL B 1 272 ? -32.702 -8.880 -7.360 1.00 37.07 ? 272 VAL B CG1 1 ATOM 6190 C CG2 . VAL B 1 272 ? -31.788 -11.168 -7.821 1.00 36.79 ? 272 VAL B CG2 1 ATOM 6191 N N . ALA B 1 273 ? -33.194 -9.467 -10.871 1.00 36.48 ? 273 ALA B N 1 ATOM 6192 C CA . ALA B 1 273 ? -34.051 -10.101 -11.876 1.00 36.31 ? 273 ALA B CA 1 ATOM 6193 C C . ALA B 1 273 ? -33.393 -10.163 -13.259 1.00 36.16 ? 273 ALA B C 1 ATOM 6194 O O . ALA B 1 273 ? -33.484 -11.184 -13.944 1.00 36.41 ? 273 ALA B O 1 ATOM 6195 C CB . ALA B 1 273 ? -35.380 -9.397 -11.956 1.00 36.43 ? 273 ALA B CB 1 ATOM 6196 N N . VAL B 1 274 ? -32.739 -9.070 -13.656 1.00 35.62 ? 274 VAL B N 1 ATOM 6197 C CA . VAL B 1 274 ? -31.956 -9.008 -14.897 1.00 35.11 ? 274 VAL B CA 1 ATOM 6198 C C . VAL B 1 274 ? -30.792 -10.007 -14.840 1.00 34.96 ? 274 VAL B C 1 ATOM 6199 O O . VAL B 1 274 ? -30.509 -10.718 -15.817 1.00 34.89 ? 274 VAL B O 1 ATOM 6200 C CB . VAL B 1 274 ? -31.400 -7.572 -15.135 1.00 35.16 ? 274 VAL B CB 1 ATOM 6201 C CG1 . VAL B 1 274 ? -30.582 -7.492 -16.414 1.00 34.88 ? 274 VAL B CG1 1 ATOM 6202 C CG2 . VAL B 1 274 ? -32.531 -6.555 -15.158 1.00 35.34 ? 274 VAL B CG2 1 ATOM 6203 N N . ILE B 1 275 ? -30.134 -10.068 -13.684 1.00 34.39 ? 275 ILE B N 1 ATOM 6204 C CA . ILE B 1 275 ? -29.010 -10.973 -13.492 1.00 33.91 ? 275 ILE B CA 1 ATOM 6205 C C . ILE B 1 275 ? -29.444 -12.443 -13.487 1.00 34.20 ? 275 ILE B C 1 ATOM 6206 O O . ILE B 1 275 ? -28.718 -13.304 -14.005 1.00 34.04 ? 275 ILE B O 1 ATOM 6207 C CB . ILE B 1 275 ? -28.185 -10.591 -12.242 1.00 33.61 ? 275 ILE B CB 1 ATOM 6208 C CG1 . ILE B 1 275 ? -27.586 -9.176 -12.409 1.00 32.23 ? 275 ILE B CG1 1 ATOM 6209 C CG2 . ILE B 1 275 ? -27.112 -11.636 -11.948 1.00 33.23 ? 275 ILE B CG2 1 ATOM 6210 C CD1 . ILE B 1 275 ? -26.713 -8.954 -13.646 1.00 29.25 ? 275 ILE B CD1 1 ATOM 6211 N N . ALA B 1 276 ? -30.629 -12.715 -12.932 1.00 34.44 ? 276 ALA B N 1 ATOM 6212 C CA . ALA B 1 276 ? -31.280 -14.039 -13.029 1.00 34.64 ? 276 ALA B CA 1 ATOM 6213 C C . ALA B 1 276 ? -31.486 -14.472 -14.484 1.00 34.94 ? 276 ALA B C 1 ATOM 6214 O O . ALA B 1 276 ? -31.230 -15.623 -14.843 1.00 34.87 ? 276 ALA B O 1 ATOM 6215 C CB . ALA B 1 276 ? -32.611 -14.035 -12.289 1.00 34.47 ? 276 ALA B CB 1 ATOM 6216 N N . GLU B 1 277 ? -31.942 -13.535 -15.315 1.00 35.45 ? 277 GLU B N 1 ATOM 6217 C CA . GLU B 1 277 ? -32.063 -13.745 -16.757 1.00 36.17 ? 277 GLU B CA 1 ATOM 6218 C C . GLU B 1 277 ? -30.698 -14.094 -17.386 1.00 35.98 ? 277 GLU B C 1 ATOM 6219 O O . GLU B 1 277 ? -30.616 -14.995 -18.220 1.00 36.01 ? 277 GLU B O 1 ATOM 6220 C CB . GLU B 1 277 ? -32.688 -12.496 -17.398 1.00 36.67 ? 277 GLU B CB 1 ATOM 6221 C CG . GLU B 1 277 ? -32.922 -12.534 -18.903 1.00 38.78 ? 277 GLU B CG 1 ATOM 6222 C CD . GLU B 1 277 ? -33.384 -11.173 -19.451 1.00 42.34 ? 277 GLU B CD 1 ATOM 6223 O OE1 . GLU B 1 277 ? -32.572 -10.211 -19.479 1.00 42.22 ? 277 GLU B OE1 1 ATOM 6224 O OE2 . GLU B 1 277 ? -34.566 -11.072 -19.867 1.00 44.77 ? 277 GLU B OE2 1 ATOM 6225 N N . SER B 1 278 ? -29.639 -13.397 -16.962 1.00 35.92 ? 278 SER B N 1 ATOM 6226 C CA . SER B 1 278 ? -28.271 -13.618 -17.469 1.00 35.59 ? 278 SER B CA 1 ATOM 6227 C C . SER B 1 278 ? -27.679 -14.966 -17.052 1.00 35.71 ? 278 SER B C 1 ATOM 6228 O O . SER B 1 278 ? -26.885 -15.560 -17.802 1.00 35.64 ? 278 SER B O 1 ATOM 6229 C CB . SER B 1 278 ? -27.333 -12.496 -17.018 1.00 35.57 ? 278 SER B CB 1 ATOM 6230 O OG . SER B 1 278 ? -27.770 -11.240 -17.495 1.00 35.24 ? 278 SER B OG 1 ATOM 6231 N N . ILE B 1 279 ? -28.055 -15.431 -15.858 1.00 35.60 ? 279 ILE B N 1 ATOM 6232 C CA . ILE B 1 279 ? -27.632 -16.737 -15.346 1.00 35.63 ? 279 ILE B CA 1 ATOM 6233 C C . ILE B 1 279 ? -28.200 -17.877 -16.211 1.00 35.95 ? 279 ILE B C 1 ATOM 6234 O O . ILE B 1 279 ? -27.516 -18.869 -16.485 1.00 36.10 ? 279 ILE B O 1 ATOM 6235 C CB . ILE B 1 279 ? -28.038 -16.928 -13.851 1.00 35.61 ? 279 ILE B CB 1 ATOM 6236 C CG1 . ILE B 1 279 ? -27.297 -15.942 -12.941 1.00 35.42 ? 279 ILE B CG1 1 ATOM 6237 C CG2 . ILE B 1 279 ? -27.800 -18.377 -13.379 1.00 35.24 ? 279 ILE B CG2 1 ATOM 6238 C CD1 . ILE B 1 279 ? -25.829 -16.286 -12.687 1.00 34.97 ? 279 ILE B CD1 1 ATOM 6239 N N . ARG B 1 280 ? -29.446 -17.724 -16.645 1.00 36.22 ? 280 ARG B N 1 ATOM 6240 C CA . ARG B 1 280 ? -30.094 -18.727 -17.487 1.00 36.56 ? 280 ARG B CA 1 ATOM 6241 C C . ARG B 1 280 ? -29.456 -18.800 -18.862 1.00 36.40 ? 280 ARG B C 1 ATOM 6242 O O . ARG B 1 280 ? -29.259 -19.890 -19.414 1.00 36.25 ? 280 ARG B O 1 ATOM 6243 C CB . ARG B 1 280 ? -31.591 -18.456 -17.581 1.00 36.73 ? 280 ARG B CB 1 ATOM 6244 C CG . ARG B 1 280 ? -32.272 -18.719 -16.264 1.00 38.29 ? 280 ARG B CG 1 ATOM 6245 C CD . ARG B 1 280 ? -33.762 -18.504 -16.303 1.00 41.94 ? 280 ARG B CD 1 ATOM 6246 N NE . ARG B 1 280 ? -34.379 -19.360 -15.291 1.00 46.44 ? 280 ARG B NE 1 ATOM 6247 C CZ . ARG B 1 280 ? -34.590 -19.007 -14.027 1.00 48.69 ? 280 ARG B CZ 1 ATOM 6248 N NH1 . ARG B 1 280 ? -34.255 -17.789 -13.614 1.00 50.48 ? 280 ARG B NH1 1 ATOM 6249 N NH2 . ARG B 1 280 ? -35.149 -19.865 -13.181 1.00 48.95 ? 280 ARG B NH2 1 ATOM 6250 N N . MET B 1 281 ? -29.126 -17.629 -19.398 1.00 36.34 ? 281 MET B N 1 ATOM 6251 C CA . MET B 1 281 ? -28.387 -17.512 -20.651 1.00 36.51 ? 281 MET B CA 1 ATOM 6252 C C . MET B 1 281 ? -27.069 -18.292 -20.559 1.00 36.38 ? 281 MET B C 1 ATOM 6253 O O . MET B 1 281 ? -26.741 -19.071 -21.455 1.00 36.08 ? 281 MET B O 1 ATOM 6254 C CB . MET B 1 281 ? -28.138 -16.028 -20.960 1.00 36.65 ? 281 MET B CB 1 ATOM 6255 C CG . MET B 1 281 ? -27.372 -15.726 -22.242 1.00 37.44 ? 281 MET B CG 1 ATOM 6256 S SD . MET B 1 281 ? -28.211 -16.219 -23.758 1.00 40.81 ? 281 MET B SD 1 ATOM 6257 C CE . MET B 1 281 ? -29.615 -15.103 -23.817 1.00 38.94 ? 281 MET B CE 1 ATOM 6258 N N . ALA B 1 282 ? -26.351 -18.094 -19.451 1.00 36.44 ? 282 ALA B N 1 ATOM 6259 C CA . ALA B 1 282 ? -25.067 -18.742 -19.195 1.00 36.72 ? 282 ALA B CA 1 ATOM 6260 C C . ALA B 1 282 ? -25.164 -20.271 -19.157 1.00 36.98 ? 282 ALA B C 1 ATOM 6261 O O . ALA B 1 282 ? -24.312 -20.974 -19.719 1.00 36.74 ? 282 ALA B O 1 ATOM 6262 C CB . ALA B 1 282 ? -24.457 -18.208 -17.898 1.00 36.61 ? 282 ALA B CB 1 ATOM 6263 N N . MET B 1 283 ? -26.204 -20.770 -18.492 1.00 37.27 ? 283 MET B N 1 ATOM 6264 C CA . MET B 1 283 ? -26.485 -22.192 -18.458 1.00 37.84 ? 283 MET B CA 1 ATOM 6265 C C . MET B 1 283 ? -26.779 -22.704 -19.864 1.00 37.87 ? 283 MET B C 1 ATOM 6266 O O . MET B 1 283 ? -26.239 -23.736 -20.273 1.00 37.97 ? 283 MET B O 1 ATOM 6267 C CB . MET B 1 283 ? -27.662 -22.482 -17.529 1.00 38.17 ? 283 MET B CB 1 ATOM 6268 C CG . MET B 1 283 ? -27.391 -22.168 -16.071 1.00 39.67 ? 283 MET B CG 1 ATOM 6269 S SD . MET B 1 283 ? -28.671 -22.821 -14.989 1.00 42.45 ? 283 MET B SD 1 ATOM 6270 C CE . MET B 1 283 ? -30.015 -21.675 -15.256 1.00 42.98 ? 283 MET B CE 1 ATOM 6271 N N . GLY B 1 284 ? -27.619 -21.968 -20.597 1.00 37.73 ? 284 GLY B N 1 ATOM 6272 C CA . GLY B 1 284 ? -27.953 -22.297 -21.977 1.00 37.78 ? 284 GLY B CA 1 ATOM 6273 C C . GLY B 1 284 ? -26.728 -22.328 -22.874 1.00 38.03 ? 284 GLY B C 1 ATOM 6274 O O . GLY B 1 284 ? -26.580 -23.228 -23.710 1.00 38.16 ? 284 GLY B O 1 ATOM 6275 N N . LEU B 1 285 ? -25.848 -21.346 -22.694 1.00 37.98 ? 285 LEU B N 1 ATOM 6276 C CA . LEU B 1 285 ? -24.611 -21.260 -23.462 1.00 37.99 ? 285 LEU B CA 1 ATOM 6277 C C . LEU B 1 285 ? -23.650 -22.403 -23.146 1.00 38.35 ? 285 LEU B C 1 ATOM 6278 O O . LEU B 1 285 ? -22.930 -22.866 -24.031 1.00 38.43 ? 285 LEU B O 1 ATOM 6279 C CB . LEU B 1 285 ? -23.934 -19.902 -23.244 1.00 37.68 ? 285 LEU B CB 1 ATOM 6280 C CG . LEU B 1 285 ? -24.112 -18.756 -24.252 1.00 36.72 ? 285 LEU B CG 1 ATOM 6281 C CD1 . LEU B 1 285 ? -25.253 -18.956 -25.230 1.00 35.25 ? 285 LEU B CD1 1 ATOM 6282 C CD2 . LEU B 1 285 ? -24.264 -17.432 -23.522 1.00 35.33 ? 285 LEU B CD2 1 ATOM 6283 N N . ARG B 1 286 ? -23.645 -22.850 -21.890 1.00 38.86 ? 286 ARG B N 1 ATOM 6284 C CA . ARG B 1 286 ? -22.829 -23.996 -21.468 1.00 39.47 ? 286 ARG B CA 1 ATOM 6285 C C . ARG B 1 286 ? -23.293 -25.303 -22.117 1.00 39.93 ? 286 ARG B C 1 ATOM 6286 O O . ARG B 1 286 ? -22.475 -26.102 -22.573 1.00 39.91 ? 286 ARG B O 1 ATOM 6287 C CB . ARG B 1 286 ? -22.849 -24.154 -19.951 1.00 39.36 ? 286 ARG B CB 1 ATOM 6288 C CG . ARG B 1 286 ? -21.857 -23.295 -19.210 1.00 39.55 ? 286 ARG B CG 1 ATOM 6289 C CD . ARG B 1 286 ? -21.145 -24.127 -18.159 1.00 40.04 ? 286 ARG B CD 1 ATOM 6290 N NE . ARG B 1 286 ? -19.836 -24.555 -18.635 1.00 39.75 ? 286 ARG B NE 1 ATOM 6291 C CZ . ARG B 1 286 ? -19.155 -25.600 -18.171 1.00 39.78 ? 286 ARG B CZ 1 ATOM 6292 N NH1 . ARG B 1 286 ? -19.653 -26.370 -17.211 1.00 39.25 ? 286 ARG B NH1 1 ATOM 6293 N NH2 . ARG B 1 286 ? -17.966 -25.883 -18.685 1.00 40.09 ? 286 ARG B NH2 1 ATOM 6294 N N . ILE B 1 287 ? -24.609 -25.512 -22.137 1.00 40.38 ? 287 ILE B N 1 ATOM 6295 C CA . ILE B 1 287 ? -25.221 -26.659 -22.805 1.00 40.65 ? 287 ILE B CA 1 ATOM 6296 C C . ILE B 1 287 ? -24.883 -26.663 -24.300 1.00 40.78 ? 287 ILE B C 1 ATOM 6297 O O . ILE B 1 287 ? -24.384 -27.658 -24.828 1.00 40.98 ? 287 ILE B O 1 ATOM 6298 C CB . ILE B 1 287 ? -26.768 -26.674 -22.596 1.00 40.80 ? 287 ILE B CB 1 ATOM 6299 C CG1 . ILE B 1 287 ? -27.130 -26.841 -21.107 1.00 40.69 ? 287 ILE B CG1 1 ATOM 6300 C CG2 . ILE B 1 287 ? -27.450 -27.726 -23.493 1.00 40.46 ? 287 ILE B CG2 1 ATOM 6301 C CD1 . ILE B 1 287 ? -26.502 -28.048 -20.403 1.00 41.40 ? 287 ILE B CD1 1 ATOM 6302 N N . LYS B 1 288 ? -25.148 -25.541 -24.963 1.00 40.81 ? 288 LYS B N 1 ATOM 6303 C CA . LYS B 1 288 ? -24.877 -25.384 -26.390 1.00 40.95 ? 288 LYS B CA 1 ATOM 6304 C C . LYS B 1 288 ? -23.388 -25.436 -26.748 1.00 40.41 ? 288 LYS B C 1 ATOM 6305 O O . LYS B 1 288 ? -23.029 -25.993 -27.775 1.00 40.51 ? 288 LYS B O 1 ATOM 6306 C CB . LYS B 1 288 ? -25.498 -24.082 -26.910 1.00 41.35 ? 288 LYS B CB 1 ATOM 6307 C CG . LYS B 1 288 ? -26.860 -24.235 -27.560 1.00 43.45 ? 288 LYS B CG 1 ATOM 6308 C CD . LYS B 1 288 ? -26.730 -24.732 -29.006 1.00 48.12 ? 288 LYS B CD 1 ATOM 6309 C CE . LYS B 1 288 ? -28.058 -24.642 -29.753 1.00 50.56 ? 288 LYS B CE 1 ATOM 6310 N NZ . LYS B 1 288 ? -28.608 -23.254 -29.747 1.00 52.85 ? 288 LYS B NZ 1 ATOM 6311 N N . PHE B 1 289 ? -22.528 -24.857 -25.910 1.00 39.79 ? 289 PHE B N 1 ATOM 6312 C CA . PHE B 1 289 ? -21.094 -24.786 -26.208 1.00 39.21 ? 289 PHE B CA 1 ATOM 6313 C C . PHE B 1 289 ? -20.206 -25.188 -25.019 1.00 38.53 ? 289 PHE B C 1 ATOM 6314 O O . PHE B 1 289 ? -19.470 -24.347 -24.491 1.00 38.26 ? 289 PHE B O 1 ATOM 6315 C CB . PHE B 1 289 ? -20.712 -23.372 -26.674 1.00 39.46 ? 289 PHE B CB 1 ATOM 6316 C CG . PHE B 1 289 ? -21.543 -22.851 -27.813 1.00 40.07 ? 289 PHE B CG 1 ATOM 6317 C CD1 . PHE B 1 289 ? -21.206 -23.151 -29.134 1.00 40.83 ? 289 PHE B CD1 1 ATOM 6318 C CD2 . PHE B 1 289 ? -22.654 -22.047 -27.567 1.00 40.45 ? 289 PHE B CD2 1 ATOM 6319 C CE1 . PHE B 1 289 ? -21.971 -22.668 -30.192 1.00 41.31 ? 289 PHE B CE1 1 ATOM 6320 C CE2 . PHE B 1 289 ? -23.429 -21.556 -28.619 1.00 40.96 ? 289 PHE B CE2 1 ATOM 6321 C CZ . PHE B 1 289 ? -23.087 -21.868 -29.935 1.00 41.63 ? 289 PHE B CZ 1 ATOM 6322 N N . PRO B 1 290 ? -20.243 -26.477 -24.611 1.00 37.84 ? 290 PRO B N 1 ATOM 6323 C CA . PRO B 1 290 ? -19.537 -26.872 -23.382 1.00 37.31 ? 290 PRO B CA 1 ATOM 6324 C C . PRO B 1 290 ? -18.022 -26.765 -23.518 1.00 36.92 ? 290 PRO B C 1 ATOM 6325 O O . PRO B 1 290 ? -17.308 -26.739 -22.520 1.00 37.20 ? 290 PRO B O 1 ATOM 6326 C CB . PRO B 1 290 ? -19.962 -28.328 -23.183 1.00 37.07 ? 290 PRO B CB 1 ATOM 6327 C CG . PRO B 1 290 ? -20.287 -28.812 -24.540 1.00 37.31 ? 290 PRO B CG 1 ATOM 6328 C CD . PRO B 1 290 ? -20.831 -27.639 -25.306 1.00 37.61 ? 290 PRO B CD 1 ATOM 6329 N N . THR B 1 291 ? -17.559 -26.681 -24.759 1.00 36.45 ? 291 THR B N 1 ATOM 6330 C CA . THR B 1 291 ? -16.146 -26.604 -25.096 1.00 35.71 ? 291 THR B CA 1 ATOM 6331 C C . THR B 1 291 ? -15.641 -25.156 -25.156 1.00 35.11 ? 291 THR B C 1 ATOM 6332 O O . THR B 1 291 ? -14.445 -24.903 -25.018 1.00 35.39 ? 291 THR B O 1 ATOM 6333 C CB . THR B 1 291 ? -15.896 -27.378 -26.425 1.00 35.88 ? 291 THR B CB 1 ATOM 6334 O OG1 . THR B 1 291 ? -15.039 -28.495 -26.168 1.00 36.32 ? 291 THR B OG1 1 ATOM 6335 C CG2 . THR B 1 291 ? -15.288 -26.501 -27.530 1.00 35.72 ? 291 THR B CG2 1 ATOM 6336 N N . VAL B 1 292 ? -16.557 -24.209 -25.338 1.00 34.12 ? 292 VAL B N 1 ATOM 6337 C CA . VAL B 1 292 ? -16.188 -22.802 -25.519 1.00 33.24 ? 292 VAL B CA 1 ATOM 6338 C C . VAL B 1 292 ? -16.474 -21.934 -24.281 1.00 32.39 ? 292 VAL B C 1 ATOM 6339 O O . VAL B 1 292 ? -15.666 -21.075 -23.932 1.00 32.40 ? 292 VAL B O 1 ATOM 6340 C CB . VAL B 1 292 ? -16.877 -22.179 -26.772 1.00 33.35 ? 292 VAL B CB 1 ATOM 6341 C CG1 . VAL B 1 292 ? -16.316 -20.789 -27.079 1.00 33.54 ? 292 VAL B CG1 1 ATOM 6342 C CG2 . VAL B 1 292 ? -16.706 -23.076 -27.989 1.00 33.36 ? 292 VAL B CG2 1 ATOM 6343 N N . VAL B 1 293 ? -17.608 -22.170 -23.623 1.00 31.26 ? 293 VAL B N 1 ATOM 6344 C CA . VAL B 1 293 ? -18.075 -21.313 -22.529 1.00 30.26 ? 293 VAL B CA 1 ATOM 6345 C C . VAL B 1 293 ? -17.734 -21.902 -21.154 1.00 29.83 ? 293 VAL B C 1 ATOM 6346 O O . VAL B 1 293 ? -18.350 -22.876 -20.717 1.00 29.70 ? 293 VAL B O 1 ATOM 6347 C CB . VAL B 1 293 ? -19.600 -21.050 -22.633 1.00 30.23 ? 293 VAL B CB 1 ATOM 6348 C CG1 . VAL B 1 293 ? -20.059 -20.047 -21.579 1.00 29.71 ? 293 VAL B CG1 1 ATOM 6349 C CG2 . VAL B 1 293 ? -19.955 -20.566 -24.021 1.00 29.81 ? 293 VAL B CG2 1 ATOM 6350 N N . ALA B 1 294 ? -16.761 -21.291 -20.477 1.00 29.24 ? 294 ALA B N 1 ATOM 6351 C CA . ALA B 1 294 ? -16.247 -21.816 -19.211 1.00 28.46 ? 294 ALA B CA 1 ATOM 6352 C C . ALA B 1 294 ? -17.182 -21.575 -18.022 1.00 27.91 ? 294 ALA B C 1 ATOM 6353 O O . ALA B 1 294 ? -17.167 -22.336 -17.057 1.00 27.75 ? 294 ALA B O 1 ATOM 6354 C CB . ALA B 1 294 ? -14.848 -21.259 -18.928 1.00 28.44 ? 294 ALA B CB 1 ATOM 6355 N N . GLY B 1 295 ? -17.989 -20.517 -18.091 1.00 27.40 ? 295 GLY B N 1 ATOM 6356 C CA . GLY B 1 295 ? -18.869 -20.159 -16.985 1.00 26.91 ? 295 GLY B CA 1 ATOM 6357 C C . GLY B 1 295 ? -19.323 -18.712 -16.969 1.00 26.71 ? 295 GLY B C 1 ATOM 6358 O O . GLY B 1 295 ? -19.543 -18.111 -18.028 1.00 26.88 ? 295 GLY B O 1 ATOM 6359 N N . PHE B 1 296 ? -19.461 -18.149 -15.766 1.00 26.21 ? 296 PHE B N 1 ATOM 6360 C CA . PHE B 1 296 ? -20.080 -16.827 -15.591 1.00 25.50 ? 296 PHE B CA 1 ATOM 6361 C C . PHE B 1 296 ? -19.330 -15.962 -14.575 1.00 25.39 ? 296 PHE B C 1 ATOM 6362 O O . PHE B 1 296 ? -18.664 -16.493 -13.669 1.00 25.33 ? 296 PHE B O 1 ATOM 6363 C CB . PHE B 1 296 ? -21.551 -17.002 -15.174 1.00 25.50 ? 296 PHE B CB 1 ATOM 6364 C CG . PHE B 1 296 ? -22.311 -15.711 -15.032 1.00 24.55 ? 296 PHE B CG 1 ATOM 6365 C CD1 . PHE B 1 296 ? -22.494 -15.131 -13.782 1.00 24.06 ? 296 PHE B CD1 1 ATOM 6366 C CD2 . PHE B 1 296 ? -22.849 -15.081 -16.149 1.00 24.67 ? 296 PHE B CD2 1 ATOM 6367 C CE1 . PHE B 1 296 ? -23.189 -13.942 -13.647 1.00 24.57 ? 296 PHE B CE1 1 ATOM 6368 C CE2 . PHE B 1 296 ? -23.544 -13.890 -16.029 1.00 24.86 ? 296 PHE B CE2 1 ATOM 6369 C CZ . PHE B 1 296 ? -23.717 -13.317 -14.773 1.00 24.85 ? 296 PHE B CZ 1 ATOM 6370 N N . ASP B 1 297 ? -19.461 -14.640 -14.725 1.00 25.07 ? 297 ASP B N 1 ATOM 6371 C CA . ASP B 1 297 ? -18.835 -13.640 -13.841 1.00 24.92 ? 297 ASP B CA 1 ATOM 6372 C C . ASP B 1 297 ? -19.669 -12.349 -13.793 1.00 24.81 ? 297 ASP B C 1 ATOM 6373 O O . ASP B 1 297 ? -20.414 -12.035 -14.725 1.00 24.45 ? 297 ASP B O 1 ATOM 6374 C CB . ASP B 1 297 ? -17.413 -13.325 -14.345 1.00 25.20 ? 297 ASP B CB 1 ATOM 6375 C CG . ASP B 1 297 ? -16.626 -12.386 -13.424 1.00 25.94 ? 297 ASP B CG 1 ATOM 6376 O OD1 . ASP B 1 297 ? -17.036 -12.126 -12.268 1.00 27.51 ? 297 ASP B OD1 1 ATOM 6377 O OD2 . ASP B 1 297 ? -15.560 -11.914 -13.867 1.00 26.13 ? 297 ASP B OD2 1 ATOM 6378 N N . LEU B 1 298 ? -19.536 -11.603 -12.700 1.00 24.62 ? 298 LEU B N 1 ATOM 6379 C CA . LEU B 1 298 ? -20.131 -10.280 -12.577 1.00 24.23 ? 298 LEU B CA 1 ATOM 6380 C C . LEU B 1 298 ? -19.031 -9.232 -12.573 1.00 24.22 ? 298 LEU B C 1 ATOM 6381 O O . LEU B 1 298 ? -18.064 -9.345 -11.817 1.00 24.16 ? 298 LEU B O 1 ATOM 6382 C CB . LEU B 1 298 ? -20.964 -10.188 -11.304 1.00 24.31 ? 298 LEU B CB 1 ATOM 6383 C CG . LEU B 1 298 ? -22.251 -11.014 -11.289 1.00 23.99 ? 298 LEU B CG 1 ATOM 6384 C CD1 . LEU B 1 298 ? -22.657 -11.295 -9.866 1.00 24.30 ? 298 LEU B CD1 1 ATOM 6385 C CD2 . LEU B 1 298 ? -23.386 -10.317 -12.059 1.00 24.53 ? 298 LEU B CD2 1 ATOM 6386 N N . VAL B 1 299 ? -19.177 -8.220 -13.430 1.00 24.01 ? 299 VAL B N 1 ATOM 6387 C CA . VAL B 1 299 ? -18.132 -7.210 -13.627 1.00 23.68 ? 299 VAL B CA 1 ATOM 6388 C C . VAL B 1 299 ? -18.628 -5.804 -13.307 1.00 23.87 ? 299 VAL B C 1 ATOM 6389 O O . VAL B 1 299 ? -19.793 -5.623 -12.965 1.00 23.91 ? 299 VAL B O 1 ATOM 6390 C CB . VAL B 1 299 ? -17.543 -7.264 -15.063 1.00 23.64 ? 299 VAL B CB 1 ATOM 6391 C CG1 . VAL B 1 299 ? -16.920 -8.622 -15.329 1.00 23.22 ? 299 VAL B CG1 1 ATOM 6392 C CG2 . VAL B 1 299 ? -18.610 -6.916 -16.136 1.00 23.01 ? 299 VAL B CG2 1 ATOM 6393 N N . GLY B 1 300 ? -17.747 -4.815 -13.432 1.00 24.07 ? 300 GLY B N 1 ATOM 6394 C CA . GLY B 1 300 ? -18.100 -3.425 -13.150 1.00 24.55 ? 300 GLY B CA 1 ATOM 6395 C C . GLY B 1 300 ? -17.452 -2.928 -11.872 1.00 24.88 ? 300 GLY B C 1 ATOM 6396 O O . GLY B 1 300 ? -16.760 -3.686 -11.193 1.00 24.82 ? 300 GLY B O 1 ATOM 6397 N N . HIS B 1 301 ? -17.675 -1.651 -11.556 1.00 25.27 ? 301 HIS B N 1 ATOM 6398 C CA . HIS B 1 301 ? -17.159 -1.016 -10.341 1.00 25.65 ? 301 HIS B CA 1 ATOM 6399 C C . HIS B 1 301 ? -17.740 -1.723 -9.106 1.00 26.08 ? 301 HIS B C 1 ATOM 6400 O O . HIS B 1 301 ? -18.943 -1.628 -8.826 1.00 26.34 ? 301 HIS B O 1 ATOM 6401 C CB . HIS B 1 301 ? -17.492 0.486 -10.369 1.00 25.57 ? 301 HIS B CB 1 ATOM 6402 C CG . HIS B 1 301 ? -16.712 1.329 -9.399 1.00 26.11 ? 301 HIS B CG 1 ATOM 6403 N ND1 . HIS B 1 301 ? -15.616 0.867 -8.698 1.00 26.68 ? 301 HIS B ND1 1 ATOM 6404 C CD2 . HIS B 1 301 ? -16.857 2.628 -9.044 1.00 26.13 ? 301 HIS B CD2 1 ATOM 6405 C CE1 . HIS B 1 301 ? -15.138 1.835 -7.937 1.00 25.68 ? 301 HIS B CE1 1 ATOM 6406 N NE2 . HIS B 1 301 ? -15.872 2.914 -8.129 1.00 25.88 ? 301 HIS B NE2 1 ATOM 6407 N N . GLU B 1 302 ? -16.877 -2.439 -8.383 1.00 26.25 ? 302 GLU B N 1 ATOM 6408 C CA . GLU B 1 302 ? -17.308 -3.282 -7.272 1.00 26.79 ? 302 GLU B CA 1 ATOM 6409 C C . GLU B 1 302 ? -17.772 -2.476 -6.049 1.00 27.19 ? 302 GLU B C 1 ATOM 6410 O O . GLU B 1 302 ? -18.747 -2.848 -5.385 1.00 26.94 ? 302 GLU B O 1 ATOM 6411 C CB . GLU B 1 302 ? -16.207 -4.285 -6.891 1.00 26.72 ? 302 GLU B CB 1 ATOM 6412 C CG . GLU B 1 302 ? -16.708 -5.508 -6.089 1.00 27.25 ? 302 GLU B CG 1 ATOM 6413 C CD . GLU B 1 302 ? -15.594 -6.493 -5.673 1.00 27.67 ? 302 GLU B CD 1 ATOM 6414 O OE1 . GLU B 1 302 ? -14.480 -6.421 -6.232 1.00 27.89 ? 302 GLU B OE1 1 ATOM 6415 O OE2 . GLU B 1 302 ? -15.839 -7.344 -4.781 1.00 26.89 ? 302 GLU B OE2 1 ATOM 6416 N N . ASP B 1 303 ? -17.079 -1.373 -5.769 1.00 27.70 ? 303 ASP B N 1 ATOM 6417 C CA . ASP B 1 303 ? -17.425 -0.501 -4.646 1.00 28.51 ? 303 ASP B CA 1 ATOM 6418 C C . ASP B 1 303 ? -18.850 0.047 -4.721 1.00 28.71 ? 303 ASP B C 1 ATOM 6419 O O . ASP B 1 303 ? -19.529 0.127 -3.702 1.00 28.80 ? 303 ASP B O 1 ATOM 6420 C CB . ASP B 1 303 ? -16.437 0.671 -4.538 1.00 28.60 ? 303 ASP B CB 1 ATOM 6421 C CG . ASP B 1 303 ? -15.137 0.299 -3.833 1.00 29.55 ? 303 ASP B CG 1 ATOM 6422 O OD1 . ASP B 1 303 ? -14.921 -0.882 -3.479 1.00 30.13 ? 303 ASP B OD1 1 ATOM 6423 O OD2 . ASP B 1 303 ? -14.316 1.209 -3.638 1.00 30.57 ? 303 ASP B OD2 1 ATOM 6424 N N . THR B 1 304 ? -19.298 0.407 -5.924 1.00 29.04 ? 304 THR B N 1 ATOM 6425 C CA . THR B 1 304 ? -20.562 1.135 -6.104 1.00 29.22 ? 304 THR B CA 1 ATOM 6426 C C . THR B 1 304 ? -21.760 0.270 -6.526 1.00 29.71 ? 304 THR B C 1 ATOM 6427 O O . THR B 1 304 ? -22.900 0.719 -6.447 1.00 29.89 ? 304 THR B O 1 ATOM 6428 C CB . THR B 1 304 ? -20.394 2.280 -7.127 1.00 29.04 ? 304 THR B CB 1 ATOM 6429 O OG1 . THR B 1 304 ? -19.819 1.757 -8.330 1.00 28.78 ? 304 THR B OG1 1 ATOM 6430 C CG2 . THR B 1 304 ? -19.493 3.373 -6.578 1.00 28.08 ? 304 THR B CG2 1 ATOM 6431 N N . GLY B 1 305 ? -21.503 -0.953 -6.988 1.00 30.11 ? 305 GLY B N 1 ATOM 6432 C CA . GLY B 1 305 ? -22.559 -1.840 -7.480 1.00 30.64 ? 305 GLY B CA 1 ATOM 6433 C C . GLY B 1 305 ? -23.090 -2.767 -6.403 1.00 31.14 ? 305 GLY B C 1 ATOM 6434 O O . GLY B 1 305 ? -22.762 -2.608 -5.229 1.00 31.28 ? 305 GLY B O 1 ATOM 6435 N N . HIS B 1 306 ? -23.911 -3.737 -6.797 1.00 31.48 ? 306 HIS B N 1 ATOM 6436 C CA . HIS B 1 306 ? -24.445 -4.726 -5.855 1.00 32.30 ? 306 HIS B CA 1 ATOM 6437 C C . HIS B 1 306 ? -23.364 -5.716 -5.415 1.00 32.18 ? 306 HIS B C 1 ATOM 6438 O O . HIS B 1 306 ? -22.385 -5.941 -6.128 1.00 32.30 ? 306 HIS B O 1 ATOM 6439 C CB . HIS B 1 306 ? -25.621 -5.493 -6.473 1.00 32.58 ? 306 HIS B CB 1 ATOM 6440 C CG . HIS B 1 306 ? -26.898 -4.714 -6.528 1.00 34.70 ? 306 HIS B CG 1 ATOM 6441 N ND1 . HIS B 1 306 ? -27.316 -4.046 -7.659 1.00 36.47 ? 306 HIS B ND1 1 ATOM 6442 C CD2 . HIS B 1 306 ? -27.858 -4.511 -5.595 1.00 36.76 ? 306 HIS B CD2 1 ATOM 6443 C CE1 . HIS B 1 306 ? -28.472 -3.452 -7.416 1.00 37.70 ? 306 HIS B CE1 1 ATOM 6444 N NE2 . HIS B 1 306 ? -28.825 -3.723 -6.172 1.00 38.08 ? 306 HIS B NE2 1 ATOM 6445 N N . SER B 1 307 ? -23.552 -6.307 -4.240 1.00 32.31 ? 307 SER B N 1 ATOM 6446 C CA . SER B 1 307 ? -22.649 -7.343 -3.731 1.00 32.48 ? 307 SER B CA 1 ATOM 6447 C C . SER B 1 307 ? -23.109 -8.731 -4.176 1.00 32.72 ? 307 SER B C 1 ATOM 6448 O O . SER B 1 307 ? -24.242 -8.915 -4.623 1.00 32.76 ? 307 SER B O 1 ATOM 6449 C CB . SER B 1 307 ? -22.601 -7.299 -2.211 1.00 32.23 ? 307 SER B CB 1 ATOM 6450 O OG . SER B 1 307 ? -23.812 -7.796 -1.671 1.00 32.69 ? 307 SER B OG 1 ATOM 6451 N N . LEU B 1 308 ? -22.230 -9.715 -4.038 1.00 32.96 ? 308 LEU B N 1 ATOM 6452 C CA . LEU B 1 308 ? -22.588 -11.084 -4.377 1.00 33.04 ? 308 LEU B CA 1 ATOM 6453 C C . LEU B 1 308 ? -23.742 -11.576 -3.511 1.00 33.63 ? 308 LEU B C 1 ATOM 6454 O O . LEU B 1 308 ? -24.595 -12.330 -3.978 1.00 33.66 ? 308 LEU B O 1 ATOM 6455 C CB . LEU B 1 308 ? -21.386 -12.017 -4.249 1.00 32.51 ? 308 LEU B CB 1 ATOM 6456 C CG . LEU B 1 308 ? -20.224 -11.798 -5.213 1.00 31.59 ? 308 LEU B CG 1 ATOM 6457 C CD1 . LEU B 1 308 ? -19.171 -12.874 -5.010 1.00 29.75 ? 308 LEU B CD1 1 ATOM 6458 C CD2 . LEU B 1 308 ? -20.706 -11.773 -6.656 1.00 30.66 ? 308 LEU B CD2 1 ATOM 6459 N N . HIS B 1 309 ? -23.763 -11.140 -2.255 1.00 34.26 ? 309 HIS B N 1 ATOM 6460 C CA . HIS B 1 309 ? -24.853 -11.471 -1.351 1.00 35.18 ? 309 HIS B CA 1 ATOM 6461 C C . HIS B 1 309 ? -26.181 -10.951 -1.885 1.00 35.13 ? 309 HIS B C 1 ATOM 6462 O O . HIS B 1 309 ? -27.158 -11.687 -1.924 1.00 35.11 ? 309 HIS B O 1 ATOM 6463 C CB . HIS B 1 309 ? -24.589 -10.907 0.041 1.00 35.62 ? 309 HIS B CB 1 ATOM 6464 C CG . HIS B 1 309 ? -25.526 -11.420 1.086 1.00 37.98 ? 309 HIS B CG 1 ATOM 6465 N ND1 . HIS B 1 309 ? -25.403 -12.676 1.644 1.00 40.36 ? 309 HIS B ND1 1 ATOM 6466 C CD2 . HIS B 1 309 ? -26.605 -10.851 1.673 1.00 39.55 ? 309 HIS B CD2 1 ATOM 6467 C CE1 . HIS B 1 309 ? -26.364 -12.858 2.531 1.00 40.37 ? 309 HIS B CE1 1 ATOM 6468 N NE2 . HIS B 1 309 ? -27.108 -11.766 2.567 1.00 41.00 ? 309 HIS B NE2 1 ATOM 6469 N N . ASP B 1 310 ? -26.200 -9.685 -2.306 1.00 35.37 ? 310 ASP B N 1 ATOM 6470 C CA . ASP B 1 310 ? -27.377 -9.062 -2.926 1.00 35.60 ? 310 ASP B CA 1 ATOM 6471 C C . ASP B 1 310 ? -27.977 -9.943 -4.018 1.00 35.54 ? 310 ASP B C 1 ATOM 6472 O O . ASP B 1 310 ? -29.194 -9.981 -4.192 1.00 35.41 ? 310 ASP B O 1 ATOM 6473 C CB . ASP B 1 310 ? -27.021 -7.694 -3.527 1.00 35.78 ? 310 ASP B CB 1 ATOM 6474 C CG . ASP B 1 310 ? -26.698 -6.643 -2.476 1.00 36.76 ? 310 ASP B CG 1 ATOM 6475 O OD1 . ASP B 1 310 ? -27.141 -6.770 -1.315 1.00 38.55 ? 310 ASP B OD1 1 ATOM 6476 O OD2 . ASP B 1 310 ? -26.009 -5.663 -2.819 1.00 38.00 ? 310 ASP B OD2 1 ATOM 6477 N N . TYR B 1 311 ? -27.108 -10.654 -4.735 1.00 35.64 ? 311 TYR B N 1 ATOM 6478 C CA . TYR B 1 311 ? -27.498 -11.488 -5.862 1.00 35.74 ? 311 TYR B CA 1 ATOM 6479 C C . TYR B 1 311 ? -27.759 -12.960 -5.520 1.00 36.57 ? 311 TYR B C 1 ATOM 6480 O O . TYR B 1 311 ? -28.007 -13.759 -6.429 1.00 36.64 ? 311 TYR B O 1 ATOM 6481 C CB . TYR B 1 311 ? -26.428 -11.411 -6.957 1.00 35.35 ? 311 TYR B CB 1 ATOM 6482 C CG . TYR B 1 311 ? -26.401 -10.129 -7.776 1.00 33.88 ? 311 TYR B CG 1 ATOM 6483 C CD1 . TYR B 1 311 ? -27.552 -9.644 -8.412 1.00 32.21 ? 311 TYR B CD1 1 ATOM 6484 C CD2 . TYR B 1 311 ? -25.209 -9.428 -7.955 1.00 32.50 ? 311 TYR B CD2 1 ATOM 6485 C CE1 . TYR B 1 311 ? -27.516 -8.480 -9.168 1.00 31.12 ? 311 TYR B CE1 1 ATOM 6486 C CE2 . TYR B 1 311 ? -25.163 -8.274 -8.722 1.00 31.67 ? 311 TYR B CE2 1 ATOM 6487 C CZ . TYR B 1 311 ? -26.316 -7.808 -9.326 1.00 30.86 ? 311 TYR B CZ 1 ATOM 6488 O OH . TYR B 1 311 ? -26.259 -6.668 -10.086 1.00 30.24 ? 311 TYR B OH 1 ATOM 6489 N N . LYS B 1 312 ? -27.715 -13.323 -4.236 1.00 37.60 ? 312 LYS B N 1 ATOM 6490 C CA . LYS B 1 312 ? -27.835 -14.732 -3.822 1.00 38.97 ? 312 LYS B CA 1 ATOM 6491 C C . LYS B 1 312 ? -28.948 -15.495 -4.541 1.00 39.30 ? 312 LYS B C 1 ATOM 6492 O O . LYS B 1 312 ? -28.712 -16.579 -5.079 1.00 39.31 ? 312 LYS B O 1 ATOM 6493 C CB . LYS B 1 312 ? -28.015 -14.875 -2.307 1.00 39.27 ? 312 LYS B CB 1 ATOM 6494 C CG . LYS B 1 312 ? -28.015 -16.344 -1.831 1.00 41.76 ? 312 LYS B CG 1 ATOM 6495 C CD . LYS B 1 312 ? -28.177 -16.492 -0.312 1.00 45.27 ? 312 LYS B CD 1 ATOM 6496 C CE . LYS B 1 312 ? -29.621 -16.255 0.134 1.00 47.24 ? 312 LYS B CE 1 ATOM 6497 N NZ . LYS B 1 312 ? -29.723 -16.074 1.620 1.00 49.71 ? 312 LYS B NZ 1 ATOM 6498 N N . GLU B 1 313 ? -30.154 -14.930 -4.541 1.00 39.88 ? 313 GLU B N 1 ATOM 6499 C CA . GLU B 1 313 ? -31.297 -15.564 -5.196 1.00 40.42 ? 313 GLU B CA 1 ATOM 6500 C C . GLU B 1 313 ? -30.963 -16.004 -6.617 1.00 39.76 ? 313 GLU B C 1 ATOM 6501 O O . GLU B 1 313 ? -31.154 -17.165 -6.962 1.00 39.99 ? 313 GLU B O 1 ATOM 6502 C CB . GLU B 1 313 ? -32.529 -14.653 -5.167 1.00 40.96 ? 313 GLU B CB 1 ATOM 6503 C CG . GLU B 1 313 ? -33.149 -14.527 -3.783 1.00 44.17 ? 313 GLU B CG 1 ATOM 6504 C CD . GLU B 1 313 ? -33.359 -15.888 -3.115 1.00 48.63 ? 313 GLU B CD 1 ATOM 6505 O OE1 . GLU B 1 313 ? -34.396 -16.541 -3.392 1.00 50.75 ? 313 GLU B OE1 1 ATOM 6506 O OE2 . GLU B 1 313 ? -32.492 -16.305 -2.311 1.00 49.78 ? 313 GLU B OE2 1 ATOM 6507 N N . ALA B 1 314 ? -30.430 -15.081 -7.415 1.00 38.91 ? 314 ALA B N 1 ATOM 6508 C CA . ALA B 1 314 ? -30.070 -15.350 -8.804 1.00 37.98 ? 314 ALA B CA 1 ATOM 6509 C C . ALA B 1 314 ? -28.889 -16.318 -8.951 1.00 37.43 ? 314 ALA B C 1 ATOM 6510 O O . ALA B 1 314 ? -28.901 -17.190 -9.820 1.00 36.98 ? 314 ALA B O 1 ATOM 6511 C CB . ALA B 1 314 ? -29.786 -14.037 -9.538 1.00 37.98 ? 314 ALA B CB 1 ATOM 6512 N N . LEU B 1 315 ? -27.877 -16.165 -8.098 1.00 36.98 ? 315 LEU B N 1 ATOM 6513 C CA . LEU B 1 315 ? -26.656 -16.982 -8.189 1.00 36.76 ? 315 LEU B CA 1 ATOM 6514 C C . LEU B 1 315 ? -26.846 -18.433 -7.737 1.00 37.38 ? 315 LEU B C 1 ATOM 6515 O O . LEU B 1 315 ? -26.001 -19.295 -8.009 1.00 37.12 ? 315 LEU B O 1 ATOM 6516 C CB . LEU B 1 315 ? -25.490 -16.318 -7.436 1.00 36.14 ? 315 LEU B CB 1 ATOM 6517 C CG . LEU B 1 315 ? -25.056 -14.939 -7.948 1.00 33.84 ? 315 LEU B CG 1 ATOM 6518 C CD1 . LEU B 1 315 ? -23.900 -14.374 -7.132 1.00 31.50 ? 315 LEU B CD1 1 ATOM 6519 C CD2 . LEU B 1 315 ? -24.699 -14.984 -9.426 1.00 30.12 ? 315 LEU B CD2 1 ATOM 6520 N N . MET B 1 316 ? -27.963 -18.693 -7.061 1.00 38.26 ? 316 MET B N 1 ATOM 6521 C CA . MET B 1 316 ? -28.299 -20.034 -6.587 1.00 39.38 ? 316 MET B CA 1 ATOM 6522 C C . MET B 1 316 ? -29.187 -20.816 -7.565 1.00 39.93 ? 316 MET B C 1 ATOM 6523 O O . MET B 1 316 ? -29.404 -22.019 -7.380 1.00 39.93 ? 316 MET B O 1 ATOM 6524 C CB . MET B 1 316 ? -28.959 -19.968 -5.202 1.00 39.55 ? 316 MET B CB 1 ATOM 6525 C CG . MET B 1 316 ? -28.017 -19.589 -4.055 1.00 40.64 ? 316 MET B CG 1 ATOM 6526 S SD . MET B 1 316 ? -26.541 -20.625 -3.963 1.00 44.26 ? 316 MET B SD 1 ATOM 6527 C CE . MET B 1 316 ? -27.251 -22.209 -3.482 1.00 43.87 ? 316 MET B CE 1 ATOM 6528 N N . ILE B 1 317 ? -29.690 -20.134 -8.597 1.00 40.73 ? 317 ILE B N 1 ATOM 6529 C CA . ILE B 1 317 ? -30.535 -20.760 -9.626 1.00 41.58 ? 317 ILE B CA 1 ATOM 6530 C C . ILE B 1 317 ? -29.954 -22.072 -10.190 1.00 42.84 ? 317 ILE B C 1 ATOM 6531 O O . ILE B 1 317 ? -30.665 -23.079 -10.219 1.00 43.19 ? 317 ILE B O 1 ATOM 6532 C CB . ILE B 1 317 ? -30.920 -19.775 -10.769 1.00 41.34 ? 317 ILE B CB 1 ATOM 6533 C CG1 . ILE B 1 317 ? -31.968 -18.776 -10.279 1.00 40.16 ? 317 ILE B CG1 1 ATOM 6534 C CG2 . ILE B 1 317 ? -31.440 -20.528 -12.000 1.00 41.12 ? 317 ILE B CG2 1 ATOM 6535 C CD1 . ILE B 1 317 ? -32.199 -17.606 -11.220 1.00 39.06 ? 317 ILE B CD1 1 ATOM 6536 N N . PRO B 1 318 ? -28.669 -22.077 -10.623 1.00 43.95 ? 318 PRO B N 1 ATOM 6537 C CA . PRO B 1 318 ? -28.139 -23.354 -11.118 1.00 44.82 ? 318 PRO B CA 1 ATOM 6538 C C . PRO B 1 318 ? -28.233 -24.478 -10.086 1.00 45.72 ? 318 PRO B C 1 ATOM 6539 O O . PRO B 1 318 ? -28.665 -25.575 -10.425 1.00 45.93 ? 318 PRO B O 1 ATOM 6540 C CB . PRO B 1 318 ? -26.673 -23.033 -11.427 1.00 44.79 ? 318 PRO B CB 1 ATOM 6541 C CG . PRO B 1 318 ? -26.659 -21.575 -11.681 1.00 44.25 ? 318 PRO B CG 1 ATOM 6542 C CD . PRO B 1 318 ? -27.671 -20.998 -10.743 1.00 43.83 ? 318 PRO B CD 1 ATOM 6543 N N . ALA B 1 319 ? -27.847 -24.197 -8.843 1.00 46.83 ? 319 ALA B N 1 ATOM 6544 C CA . ALA B 1 319 ? -27.873 -25.199 -7.773 1.00 47.98 ? 319 ALA B CA 1 ATOM 6545 C C . ALA B 1 319 ? -29.279 -25.769 -7.547 1.00 48.78 ? 319 ALA B C 1 ATOM 6546 O O . ALA B 1 319 ? -29.449 -26.984 -7.409 1.00 48.90 ? 319 ALA B O 1 ATOM 6547 C CB . ALA B 1 319 ? -27.311 -24.621 -6.485 1.00 47.79 ? 319 ALA B CB 1 ATOM 6548 N N . LYS B 1 320 ? -30.278 -24.887 -7.533 1.00 49.60 ? 320 LYS B N 1 ATOM 6549 C CA . LYS B 1 320 ? -31.680 -25.288 -7.412 1.00 50.32 ? 320 LYS B CA 1 ATOM 6550 C C . LYS B 1 320 ? -32.176 -26.120 -8.604 1.00 50.58 ? 320 LYS B C 1 ATOM 6551 O O . LYS B 1 320 ? -33.126 -26.883 -8.466 1.00 51.00 ? 320 LYS B O 1 ATOM 6552 C CB . LYS B 1 320 ? -32.579 -24.062 -7.226 1.00 50.52 ? 320 LYS B CB 1 ATOM 6553 C CG . LYS B 1 320 ? -32.477 -23.392 -5.857 1.00 51.22 ? 320 LYS B CG 1 ATOM 6554 C CD . LYS B 1 320 ? -33.367 -22.141 -5.769 1.00 52.81 ? 320 LYS B CD 1 ATOM 6555 C CE . LYS B 1 320 ? -32.737 -20.937 -6.480 1.00 53.81 ? 320 LYS B CE 1 ATOM 6556 N NZ . LYS B 1 320 ? -33.556 -19.688 -6.400 1.00 53.90 ? 320 LYS B NZ 1 ATOM 6557 N N . ASP B 1 321 ? -31.546 -25.965 -9.768 1.00 50.66 ? 321 ASP B N 1 ATOM 6558 C CA . ASP B 1 321 ? -31.882 -26.768 -10.948 1.00 50.60 ? 321 ASP B CA 1 ATOM 6559 C C . ASP B 1 321 ? -30.995 -28.004 -11.041 1.00 50.06 ? 321 ASP B C 1 ATOM 6560 O O . ASP B 1 321 ? -31.064 -28.751 -12.020 1.00 50.18 ? 321 ASP B O 1 ATOM 6561 C CB . ASP B 1 321 ? -31.737 -25.947 -12.235 1.00 51.12 ? 321 ASP B CB 1 ATOM 6562 C CG . ASP B 1 321 ? -32.738 -24.804 -12.328 1.00 52.93 ? 321 ASP B CG 1 ATOM 6563 O OD1 . ASP B 1 321 ? -33.548 -24.623 -11.389 1.00 55.31 ? 321 ASP B OD1 1 ATOM 6564 O OD2 . ASP B 1 321 ? -32.711 -24.080 -13.350 1.00 54.61 ? 321 ASP B OD2 1 ATOM 6565 N N . GLY B 1 322 ? -30.157 -28.208 -10.025 1.00 49.31 ? 322 GLY B N 1 ATOM 6566 C CA . GLY B 1 322 ? -29.211 -29.322 -10.004 1.00 48.18 ? 322 GLY B CA 1 ATOM 6567 C C . GLY B 1 322 ? -28.161 -29.236 -11.099 1.00 47.34 ? 322 GLY B C 1 ATOM 6568 O O . GLY B 1 322 ? -27.675 -30.255 -11.584 1.00 47.38 ? 322 GLY B O 1 ATOM 6569 N N . VAL B 1 323 ? -27.812 -28.012 -11.487 1.00 46.35 ? 323 VAL B N 1 ATOM 6570 C CA . VAL B 1 323 ? -26.824 -27.778 -12.540 1.00 45.14 ? 323 VAL B CA 1 ATOM 6571 C C . VAL B 1 323 ? -25.619 -27.034 -11.969 1.00 44.00 ? 323 VAL B C 1 ATOM 6572 O O . VAL B 1 323 ? -25.768 -26.172 -11.098 1.00 44.21 ? 323 VAL B O 1 ATOM 6573 C CB . VAL B 1 323 ? -27.445 -26.993 -13.728 1.00 45.39 ? 323 VAL B CB 1 ATOM 6574 C CG1 . VAL B 1 323 ? -26.396 -26.659 -14.785 1.00 45.58 ? 323 VAL B CG1 1 ATOM 6575 C CG2 . VAL B 1 323 ? -28.587 -27.791 -14.354 1.00 45.31 ? 323 VAL B CG2 1 ATOM 6576 N N . LYS B 1 324 ? -24.427 -27.383 -12.444 1.00 42.31 ? 324 LYS B N 1 ATOM 6577 C CA . LYS B 1 324 ? -23.218 -26.662 -12.066 1.00 40.68 ? 324 LYS B CA 1 ATOM 6578 C C . LYS B 1 324 ? -22.828 -25.631 -13.124 1.00 39.04 ? 324 LYS B C 1 ATOM 6579 O O . LYS B 1 324 ? -22.397 -25.976 -14.230 1.00 38.62 ? 324 LYS B O 1 ATOM 6580 C CB . LYS B 1 324 ? -22.063 -27.626 -11.788 1.00 40.97 ? 324 LYS B CB 1 ATOM 6581 C CG . LYS B 1 324 ? -20.742 -26.938 -11.421 1.00 42.86 ? 324 LYS B CG 1 ATOM 6582 C CD . LYS B 1 324 ? -19.711 -27.938 -10.892 1.00 46.49 ? 324 LYS B CD 1 ATOM 6583 C CE . LYS B 1 324 ? -19.430 -29.077 -11.891 1.00 48.08 ? 324 LYS B CE 1 ATOM 6584 N NZ . LYS B 1 324 ? -18.800 -30.268 -11.231 1.00 48.88 ? 324 LYS B NZ 1 ATOM 6585 N N . LEU B 1 325 ? -23.013 -24.361 -12.773 1.00 37.20 ? 325 LEU B N 1 ATOM 6586 C CA . LEU B 1 325 ? -22.511 -23.250 -13.573 1.00 35.07 ? 325 LEU B CA 1 ATOM 6587 C C . LEU B 1 325 ? -21.240 -22.740 -12.899 1.00 33.73 ? 325 LEU B C 1 ATOM 6588 O O . LEU B 1 325 ? -21.312 -22.105 -11.838 1.00 33.58 ? 325 LEU B O 1 ATOM 6589 C CB . LEU B 1 325 ? -23.560 -22.135 -13.688 1.00 34.81 ? 325 LEU B CB 1 ATOM 6590 C CG . LEU B 1 325 ? -23.170 -20.808 -14.362 1.00 34.39 ? 325 LEU B CG 1 ATOM 6591 C CD1 . LEU B 1 325 ? -22.819 -20.973 -15.850 1.00 32.86 ? 325 LEU B CD1 1 ATOM 6592 C CD2 . LEU B 1 325 ? -24.276 -19.777 -14.178 1.00 33.78 ? 325 LEU B CD2 1 ATOM 6593 N N . PRO B 1 326 ? -20.069 -23.034 -13.496 1.00 32.26 ? 326 PRO B N 1 ATOM 6594 C CA . PRO B 1 326 ? -18.839 -22.565 -12.865 1.00 31.13 ? 326 PRO B CA 1 ATOM 6595 C C . PRO B 1 326 ? -18.804 -21.042 -12.810 1.00 30.03 ? 326 PRO B C 1 ATOM 6596 O O . PRO B 1 326 ? -19.355 -20.372 -13.692 1.00 29.77 ? 326 PRO B O 1 ATOM 6597 C CB . PRO B 1 326 ? -17.732 -23.120 -13.776 1.00 31.06 ? 326 PRO B CB 1 ATOM 6598 C CG . PRO B 1 326 ? -18.383 -24.244 -14.525 1.00 31.10 ? 326 PRO B CG 1 ATOM 6599 C CD . PRO B 1 326 ? -19.795 -23.811 -14.720 1.00 31.98 ? 326 PRO B CD 1 ATOM 6600 N N . TYR B 1 327 ? -18.179 -20.516 -11.761 1.00 28.71 ? 327 TYR B N 1 ATOM 6601 C CA . TYR B 1 327 ? -18.106 -19.082 -11.535 1.00 27.41 ? 327 TYR B CA 1 ATOM 6602 C C . TYR B 1 327 ? -16.661 -18.625 -11.458 1.00 26.53 ? 327 TYR B C 1 ATOM 6603 O O . TYR B 1 327 ? -15.777 -19.377 -11.031 1.00 26.11 ? 327 TYR B O 1 ATOM 6604 C CB . TYR B 1 327 ? -18.833 -18.697 -10.246 1.00 27.45 ? 327 TYR B CB 1 ATOM 6605 C CG . TYR B 1 327 ? -20.343 -18.774 -10.306 1.00 26.90 ? 327 TYR B CG 1 ATOM 6606 C CD1 . TYR B 1 327 ? -21.051 -18.146 -11.329 1.00 26.79 ? 327 TYR B CD1 1 ATOM 6607 C CD2 . TYR B 1 327 ? -21.066 -19.439 -9.312 1.00 26.89 ? 327 TYR B CD2 1 ATOM 6608 C CE1 . TYR B 1 327 ? -22.432 -18.197 -11.379 1.00 27.75 ? 327 TYR B CE1 1 ATOM 6609 C CE2 . TYR B 1 327 ? -22.455 -19.499 -9.349 1.00 26.59 ? 327 TYR B CE2 1 ATOM 6610 C CZ . TYR B 1 327 ? -23.132 -18.874 -10.389 1.00 27.67 ? 327 TYR B CZ 1 ATOM 6611 O OH . TYR B 1 327 ? -24.509 -18.917 -10.448 1.00 28.55 ? 327 TYR B OH 1 ATOM 6612 N N . PHE B 1 328 ? -16.433 -17.381 -11.874 1.00 25.65 ? 328 PHE B N 1 ATOM 6613 C CA . PHE B 1 328 ? -15.096 -16.789 -11.902 1.00 24.65 ? 328 PHE B CA 1 ATOM 6614 C C . PHE B 1 328 ? -15.140 -15.359 -11.375 1.00 24.00 ? 328 PHE B C 1 ATOM 6615 O O . PHE B 1 328 ? -14.666 -14.440 -12.028 1.00 24.60 ? 328 PHE B O 1 ATOM 6616 C CB . PHE B 1 328 ? -14.535 -16.825 -13.334 1.00 24.44 ? 328 PHE B CB 1 ATOM 6617 C CG . PHE B 1 328 ? -14.417 -18.207 -13.899 1.00 23.78 ? 328 PHE B CG 1 ATOM 6618 C CD1 . PHE B 1 328 ? -13.226 -18.904 -13.795 1.00 23.12 ? 328 PHE B CD1 1 ATOM 6619 C CD2 . PHE B 1 328 ? -15.505 -18.819 -14.525 1.00 23.21 ? 328 PHE B CD2 1 ATOM 6620 C CE1 . PHE B 1 328 ? -13.118 -20.185 -14.300 1.00 23.28 ? 328 PHE B CE1 1 ATOM 6621 C CE2 . PHE B 1 328 ? -15.406 -20.105 -15.034 1.00 22.52 ? 328 PHE B CE2 1 ATOM 6622 C CZ . PHE B 1 328 ? -14.207 -20.787 -14.921 1.00 22.96 ? 328 PHE B CZ 1 ATOM 6623 N N . PHE B 1 329 ? -15.700 -15.181 -10.186 1.00 23.09 ? 329 PHE B N 1 ATOM 6624 C CA . PHE B 1 329 ? -16.035 -13.852 -9.666 1.00 22.18 ? 329 PHE B CA 1 ATOM 6625 C C . PHE B 1 329 ? -14.877 -12.872 -9.440 1.00 21.78 ? 329 PHE B C 1 ATOM 6626 O O . PHE B 1 329 ? -13.922 -13.188 -8.743 1.00 21.63 ? 329 PHE B O 1 ATOM 6627 C CB . PHE B 1 329 ? -16.796 -13.982 -8.342 1.00 21.86 ? 329 PHE B CB 1 ATOM 6628 C CG . PHE B 1 329 ? -18.165 -14.611 -8.465 1.00 21.31 ? 329 PHE B CG 1 ATOM 6629 C CD1 . PHE B 1 329 ? -19.148 -14.041 -9.271 1.00 20.20 ? 329 PHE B CD1 1 ATOM 6630 C CD2 . PHE B 1 329 ? -18.488 -15.750 -7.724 1.00 20.73 ? 329 PHE B CD2 1 ATOM 6631 C CE1 . PHE B 1 329 ? -20.413 -14.611 -9.363 1.00 19.68 ? 329 PHE B CE1 1 ATOM 6632 C CE2 . PHE B 1 329 ? -19.762 -16.319 -7.806 1.00 19.76 ? 329 PHE B CE2 1 ATOM 6633 C CZ . PHE B 1 329 ? -20.724 -15.749 -8.628 1.00 19.21 ? 329 PHE B CZ 1 ATOM 6634 N N . HIS B 1 330 ? -14.990 -11.674 -10.014 1.00 21.63 ? 330 HIS B N 1 ATOM 6635 C CA . HIS B 1 330 ? -14.285 -10.495 -9.500 1.00 21.71 ? 330 HIS B CA 1 ATOM 6636 C C . HIS B 1 330 ? -14.686 -10.338 -8.040 1.00 21.89 ? 330 HIS B C 1 ATOM 6637 O O . HIS B 1 330 ? -15.876 -10.389 -7.711 1.00 21.89 ? 330 HIS B O 1 ATOM 6638 C CB . HIS B 1 330 ? -14.735 -9.231 -10.229 1.00 21.62 ? 330 HIS B CB 1 ATOM 6639 C CG . HIS B 1 330 ? -14.110 -9.034 -11.572 1.00 21.99 ? 330 HIS B CG 1 ATOM 6640 N ND1 . HIS B 1 330 ? -14.267 -9.929 -12.608 1.00 22.99 ? 330 HIS B ND1 1 ATOM 6641 C CD2 . HIS B 1 330 ? -13.359 -8.020 -12.059 1.00 21.32 ? 330 HIS B CD2 1 ATOM 6642 C CE1 . HIS B 1 330 ? -13.619 -9.485 -13.670 1.00 22.40 ? 330 HIS B CE1 1 ATOM 6643 N NE2 . HIS B 1 330 ? -13.063 -8.327 -13.363 1.00 22.15 ? 330 HIS B NE2 1 ATOM 6644 N N . ALA B 1 331 ? -13.709 -10.155 -7.157 1.00 21.99 ? 331 ALA B N 1 ATOM 6645 C CA . ALA B 1 331 ? -14.011 -10.082 -5.734 1.00 21.98 ? 331 ALA B CA 1 ATOM 6646 C C . ALA B 1 331 ? -12.925 -9.400 -4.928 1.00 22.00 ? 331 ALA B C 1 ATOM 6647 O O . ALA B 1 331 ? -11.739 -9.709 -5.074 1.00 21.83 ? 331 ALA B O 1 ATOM 6648 C CB . ALA B 1 331 ? -14.287 -11.483 -5.174 1.00 22.11 ? 331 ALA B CB 1 ATOM 6649 N N . GLY B 1 332 ? -13.357 -8.479 -4.067 1.00 22.23 ? 332 GLY B N 1 ATOM 6650 C CA . GLY B 1 332 ? -12.481 -7.766 -3.145 1.00 22.14 ? 332 GLY B CA 1 ATOM 6651 C C . GLY B 1 332 ? -11.533 -6.822 -3.847 1.00 22.47 ? 332 GLY B C 1 ATOM 6652 O O . GLY B 1 332 ? -10.440 -6.565 -3.346 1.00 22.81 ? 332 GLY B O 1 ATOM 6653 N N . GLU B 1 333 ? -11.943 -6.317 -5.009 1.00 22.47 ? 333 GLU B N 1 ATOM 6654 C CA . GLU B 1 333 ? -11.189 -5.302 -5.726 1.00 22.95 ? 333 GLU B CA 1 ATOM 6655 C C . GLU B 1 333 ? -11.470 -3.930 -5.078 1.00 22.59 ? 333 GLU B C 1 ATOM 6656 O O . GLU B 1 333 ? -12.108 -3.057 -5.664 1.00 22.56 ? 333 GLU B O 1 ATOM 6657 C CB . GLU B 1 333 ? -11.575 -5.331 -7.206 1.00 23.34 ? 333 GLU B CB 1 ATOM 6658 C CG . GLU B 1 333 ? -10.613 -4.622 -8.129 1.00 26.06 ? 333 GLU B CG 1 ATOM 6659 C CD . GLU B 1 333 ? -11.246 -4.260 -9.461 1.00 30.74 ? 333 GLU B CD 1 ATOM 6660 O OE1 . GLU B 1 333 ? -12.456 -4.547 -9.655 1.00 31.36 ? 333 GLU B OE1 1 ATOM 6661 O OE2 . GLU B 1 333 ? -10.527 -3.680 -10.309 1.00 32.51 ? 333 GLU B OE2 1 ATOM 6662 N N . THR B 1 334 ? -10.982 -3.760 -3.851 1.00 22.26 ? 334 THR B N 1 ATOM 6663 C CA . THR B 1 334 ? -11.306 -2.600 -3.031 1.00 21.74 ? 334 THR B CA 1 ATOM 6664 C C . THR B 1 334 ? -10.223 -2.257 -2.004 1.00 21.64 ? 334 THR B C 1 ATOM 6665 O O . THR B 1 334 ? -9.454 -3.118 -1.580 1.00 21.41 ? 334 THR B O 1 ATOM 6666 C CB . THR B 1 334 ? -12.671 -2.795 -2.279 1.00 21.81 ? 334 THR B CB 1 ATOM 6667 O OG1 . THR B 1 334 ? -12.961 -1.631 -1.483 1.00 20.94 ? 334 THR B OG1 1 ATOM 6668 C CG2 . THR B 1 334 ? -12.635 -4.045 -1.390 1.00 20.88 ? 334 THR B CG2 1 ATOM 6669 N N . ASP B 1 335 ? -10.204 -0.989 -1.601 1.00 21.76 ? 335 ASP B N 1 ATOM 6670 C CA . ASP B 1 335 ? -9.365 -0.502 -0.514 1.00 21.91 ? 335 ASP B CA 1 ATOM 6671 C C . ASP B 1 335 ? -10.079 -0.636 0.828 1.00 22.03 ? 335 ASP B C 1 ATOM 6672 O O . ASP B 1 335 ? -9.447 -0.530 1.869 1.00 22.14 ? 335 ASP B O 1 ATOM 6673 C CB . ASP B 1 335 ? -8.999 0.971 -0.743 1.00 21.51 ? 335 ASP B CB 1 ATOM 6674 C CG . ASP B 1 335 ? -7.950 1.157 -1.813 1.00 21.82 ? 335 ASP B CG 1 ATOM 6675 O OD1 . ASP B 1 335 ? -7.009 0.344 -1.882 1.00 24.30 ? 335 ASP B OD1 1 ATOM 6676 O OD2 . ASP B 1 335 ? -8.046 2.123 -2.590 1.00 21.04 ? 335 ASP B OD2 1 ATOM 6677 N N . TRP B 1 336 ? -11.400 -0.816 0.804 1.00 22.33 ? 336 TRP B N 1 ATOM 6678 C CA . TRP B 1 336 ? -12.174 -0.964 2.044 1.00 22.49 ? 336 TRP B CA 1 ATOM 6679 C C . TRP B 1 336 ? -11.901 -2.307 2.704 1.00 22.65 ? 336 TRP B C 1 ATOM 6680 O O . TRP B 1 336 ? -11.585 -3.303 2.036 1.00 22.61 ? 336 TRP B O 1 ATOM 6681 C CB . TRP B 1 336 ? -13.672 -0.747 1.806 1.00 22.39 ? 336 TRP B CB 1 ATOM 6682 C CG . TRP B 1 336 ? -13.964 0.596 1.166 1.00 23.07 ? 336 TRP B CG 1 ATOM 6683 C CD1 . TRP B 1 336 ? -14.365 0.820 -0.124 1.00 23.07 ? 336 TRP B CD1 1 ATOM 6684 C CD2 . TRP B 1 336 ? -13.833 1.893 1.772 1.00 22.95 ? 336 TRP B CD2 1 ATOM 6685 N NE1 . TRP B 1 336 ? -14.496 2.166 -0.355 1.00 22.99 ? 336 TRP B NE1 1 ATOM 6686 C CE2 . TRP B 1 336 ? -14.180 2.849 0.789 1.00 23.63 ? 336 TRP B CE2 1 ATOM 6687 C CE3 . TRP B 1 336 ? -13.461 2.338 3.049 1.00 23.46 ? 336 TRP B CE3 1 ATOM 6688 C CZ2 . TRP B 1 336 ? -14.172 4.225 1.044 1.00 23.76 ? 336 TRP B CZ2 1 ATOM 6689 C CZ3 . TRP B 1 336 ? -13.454 3.706 3.306 1.00 23.40 ? 336 TRP B CZ3 1 ATOM 6690 C CH2 . TRP B 1 336 ? -13.808 4.632 2.306 1.00 24.17 ? 336 TRP B CH2 1 ATOM 6691 N N . GLN B 1 337 ? -11.982 -2.305 4.028 1.00 23.09 ? 337 GLN B N 1 ATOM 6692 C CA . GLN B 1 337 ? -11.749 -3.485 4.842 1.00 23.36 ? 337 GLN B CA 1 ATOM 6693 C C . GLN B 1 337 ? -12.873 -3.618 5.864 1.00 23.99 ? 337 GLN B C 1 ATOM 6694 O O . GLN B 1 337 ? -13.252 -2.638 6.520 1.00 23.86 ? 337 GLN B O 1 ATOM 6695 C CB . GLN B 1 337 ? -10.384 -3.392 5.535 1.00 23.14 ? 337 GLN B CB 1 ATOM 6696 C CG . GLN B 1 337 ? -10.066 -4.569 6.460 1.00 22.78 ? 337 GLN B CG 1 ATOM 6697 C CD . GLN B 1 337 ? -8.843 -4.352 7.351 1.00 23.13 ? 337 GLN B CD 1 ATOM 6698 O OE1 . GLN B 1 337 ? -8.522 -5.203 8.192 1.00 24.25 ? 337 GLN B OE1 1 ATOM 6699 N NE2 . GLN B 1 337 ? -8.156 -3.221 7.176 1.00 21.35 ? 337 GLN B NE2 1 ATOM 6700 N N . GLY B 1 338 ? -13.404 -4.831 5.991 1.00 24.76 ? 338 GLY B N 1 ATOM 6701 C CA . GLY B 1 338 ? -14.498 -5.108 6.928 1.00 25.95 ? 338 GLY B CA 1 ATOM 6702 C C . GLY B 1 338 ? -15.870 -4.610 6.482 1.00 26.57 ? 338 GLY B C 1 ATOM 6703 O O . GLY B 1 338 ? -16.785 -4.532 7.290 1.00 26.97 ? 338 GLY B O 1 ATOM 6704 N N . THR B 1 339 ? -16.013 -4.278 5.200 1.00 27.13 ? 339 THR B N 1 ATOM 6705 C CA . THR B 1 339 ? -17.296 -3.826 4.648 1.00 27.58 ? 339 THR B CA 1 ATOM 6706 C C . THR B 1 339 ? -17.977 -4.936 3.847 1.00 27.89 ? 339 THR B C 1 ATOM 6707 O O . THR B 1 339 ? -17.465 -6.058 3.761 1.00 28.26 ? 339 THR B O 1 ATOM 6708 C CB . THR B 1 339 ? -17.146 -2.560 3.760 1.00 27.51 ? 339 THR B CB 1 ATOM 6709 O OG1 . THR B 1 339 ? -16.433 -2.894 2.563 1.00 27.50 ? 339 THR B OG1 1 ATOM 6710 C CG2 . THR B 1 339 ? -16.423 -1.436 4.510 1.00 27.35 ? 339 THR B CG2 1 ATOM 6711 N N . SER B 1 340 ? -19.133 -4.617 3.269 1.00 27.93 ? 340 SER B N 1 ATOM 6712 C CA . SER B 1 340 ? -19.886 -5.561 2.452 1.00 28.14 ? 340 SER B CA 1 ATOM 6713 C C . SER B 1 340 ? -19.170 -5.897 1.142 1.00 28.17 ? 340 SER B C 1 ATOM 6714 O O . SER B 1 340 ? -19.465 -6.919 0.521 1.00 28.41 ? 340 SER B O 1 ATOM 6715 C CB . SER B 1 340 ? -21.258 -4.982 2.134 1.00 28.11 ? 340 SER B CB 1 ATOM 6716 O OG . SER B 1 340 ? -21.114 -3.788 1.376 1.00 29.05 ? 340 SER B OG 1 ATOM 6717 N N . ILE B 1 341 ? -18.241 -5.035 0.732 1.00 27.92 ? 341 ILE B N 1 ATOM 6718 C CA . ILE B 1 341 ? -17.523 -5.190 -0.537 1.00 27.73 ? 341 ILE B CA 1 ATOM 6719 C C . ILE B 1 341 ? -16.395 -6.249 -0.468 1.00 27.90 ? 341 ILE B C 1 ATOM 6720 O O . ILE B 1 341 ? -16.323 -7.141 -1.321 1.00 27.64 ? 341 ILE B O 1 ATOM 6721 C CB . ILE B 1 341 ? -16.987 -3.830 -1.055 1.00 27.67 ? 341 ILE B CB 1 ATOM 6722 C CG1 . ILE B 1 341 ? -18.098 -2.764 -1.012 1.00 27.76 ? 341 ILE B CG1 1 ATOM 6723 C CG2 . ILE B 1 341 ? -16.424 -3.972 -2.464 1.00 26.58 ? 341 ILE B CG2 1 ATOM 6724 C CD1 . ILE B 1 341 ? -17.592 -1.333 -0.918 1.00 27.17 ? 341 ILE B CD1 1 ATOM 6725 N N . ASP B 1 342 ? -15.526 -6.163 0.539 1.00 27.88 ? 342 ASP B N 1 ATOM 6726 C CA . ASP B 1 342 ? -14.432 -7.140 0.660 1.00 27.92 ? 342 ASP B CA 1 ATOM 6727 C C . ASP B 1 342 ? -14.866 -8.536 1.116 1.00 27.77 ? 342 ASP B C 1 ATOM 6728 O O . ASP B 1 342 ? -14.147 -9.514 0.885 1.00 27.56 ? 342 ASP B O 1 ATOM 6729 C CB . ASP B 1 342 ? -13.254 -6.618 1.497 1.00 28.06 ? 342 ASP B CB 1 ATOM 6730 C CG . ASP B 1 342 ? -13.683 -5.980 2.788 1.00 28.68 ? 342 ASP B CG 1 ATOM 6731 O OD1 . ASP B 1 342 ? -13.046 -6.094 3.791 1.00 28.64 ? 342 ASP B OD1 1 ATOM 6732 O OD2 . ASP B 1 342 ? -14.669 -5.317 2.871 1.00 29.92 ? 342 ASP B OD2 1 ATOM 6733 N N . ARG B 1 343 ? -16.046 -8.630 1.730 1.00 27.72 ? 343 ARG B N 1 ATOM 6734 C CA . ARG B 1 343 ? -16.654 -9.924 2.046 1.00 27.48 ? 343 ARG B CA 1 ATOM 6735 C C . ARG B 1 343 ? -17.088 -10.686 0.786 1.00 26.88 ? 343 ARG B C 1 ATOM 6736 O O . ARG B 1 343 ? -17.337 -11.898 0.845 1.00 26.72 ? 343 ARG B O 1 ATOM 6737 C CB . ARG B 1 343 ? -17.820 -9.774 3.040 1.00 27.70 ? 343 ARG B CB 1 ATOM 6738 C CG . ARG B 1 343 ? -17.361 -9.549 4.473 1.00 29.99 ? 343 ARG B CG 1 ATOM 6739 C CD . ARG B 1 343 ? -18.476 -9.787 5.513 1.00 32.27 ? 343 ARG B CD 1 ATOM 6740 N NE . ARG B 1 343 ? -19.574 -8.824 5.398 1.00 34.21 ? 343 ARG B NE 1 ATOM 6741 C CZ . ARG B 1 343 ? -19.543 -7.573 5.854 1.00 34.36 ? 343 ARG B CZ 1 ATOM 6742 N NH1 . ARG B 1 343 ? -18.466 -7.096 6.465 1.00 35.21 ? 343 ARG B NH1 1 ATOM 6743 N NH2 . ARG B 1 343 ? -20.596 -6.789 5.687 1.00 34.69 ? 343 ARG B NH2 1 ATOM 6744 N N . ASN B 1 344 ? -17.164 -9.987 -0.347 1.00 26.23 ? 344 ASN B N 1 ATOM 6745 C CA . ASN B 1 344 ? -17.407 -10.642 -1.639 1.00 25.99 ? 344 ASN B CA 1 ATOM 6746 C C . ASN B 1 344 ? -16.448 -11.796 -1.934 1.00 26.16 ? 344 ASN B C 1 ATOM 6747 O O . ASN B 1 344 ? -16.812 -12.743 -2.634 1.00 26.00 ? 344 ASN B O 1 ATOM 6748 C CB . ASN B 1 344 ? -17.379 -9.636 -2.791 1.00 25.53 ? 344 ASN B CB 1 ATOM 6749 C CG . ASN B 1 344 ? -18.646 -8.808 -2.875 1.00 24.83 ? 344 ASN B CG 1 ATOM 6750 O OD1 . ASN B 1 344 ? -19.730 -9.274 -2.519 1.00 22.48 ? 344 ASN B OD1 1 ATOM 6751 N ND2 . ASN B 1 344 ? -18.517 -7.568 -3.361 1.00 22.58 ? 344 ASN B ND2 1 ATOM 6752 N N . ILE B 1 345 ? -15.232 -11.716 -1.394 1.00 26.51 ? 345 ILE B N 1 ATOM 6753 C CA . ILE B 1 345 ? -14.275 -12.809 -1.521 1.00 27.07 ? 345 ILE B CA 1 ATOM 6754 C C . ILE B 1 345 ? -14.818 -14.044 -0.803 1.00 27.42 ? 345 ILE B C 1 ATOM 6755 O O . ILE B 1 345 ? -14.871 -15.131 -1.379 1.00 27.87 ? 345 ILE B O 1 ATOM 6756 C CB . ILE B 1 345 ? -12.858 -12.451 -0.993 1.00 27.01 ? 345 ILE B CB 1 ATOM 6757 C CG1 . ILE B 1 345 ? -12.318 -11.181 -1.674 1.00 27.10 ? 345 ILE B CG1 1 ATOM 6758 C CG2 . ILE B 1 345 ? -11.885 -13.631 -1.214 1.00 26.67 ? 345 ILE B CG2 1 ATOM 6759 C CD1 . ILE B 1 345 ? -10.963 -10.693 -1.140 1.00 25.46 ? 345 ILE B CD1 1 ATOM 6760 N N . LEU B 1 346 ? -15.229 -13.863 0.445 1.00 27.91 ? 346 LEU B N 1 ATOM 6761 C CA . LEU B 1 346 ? -15.857 -14.926 1.219 1.00 28.33 ? 346 LEU B CA 1 ATOM 6762 C C . LEU B 1 346 ? -17.055 -15.533 0.472 1.00 28.60 ? 346 LEU B C 1 ATOM 6763 O O . LEU B 1 346 ? -17.169 -16.755 0.368 1.00 28.36 ? 346 LEU B O 1 ATOM 6764 C CB . LEU B 1 346 ? -16.275 -14.402 2.603 1.00 28.20 ? 346 LEU B CB 1 ATOM 6765 C CG . LEU B 1 346 ? -17.141 -15.288 3.512 1.00 28.45 ? 346 LEU B CG 1 ATOM 6766 C CD1 . LEU B 1 346 ? -16.427 -16.565 3.894 1.00 27.83 ? 346 LEU B CD1 1 ATOM 6767 C CD2 . LEU B 1 346 ? -17.558 -14.535 4.757 1.00 28.82 ? 346 LEU B CD2 1 ATOM 6768 N N . ASP B 1 347 ? -17.922 -14.673 -0.060 1.00 29.07 ? 347 ASP B N 1 ATOM 6769 C CA . ASP B 1 347 ? -19.128 -15.126 -0.745 1.00 29.91 ? 347 ASP B CA 1 ATOM 6770 C C . ASP B 1 347 ? -18.855 -15.787 -2.101 1.00 30.08 ? 347 ASP B C 1 ATOM 6771 O O . ASP B 1 347 ? -19.587 -16.688 -2.512 1.00 30.40 ? 347 ASP B O 1 ATOM 6772 C CB . ASP B 1 347 ? -20.161 -14.000 -0.849 1.00 30.08 ? 347 ASP B CB 1 ATOM 6773 C CG . ASP B 1 347 ? -20.873 -13.731 0.481 1.00 31.22 ? 347 ASP B CG 1 ATOM 6774 O OD1 . ASP B 1 347 ? -21.192 -14.704 1.206 1.00 31.17 ? 347 ASP B OD1 1 ATOM 6775 O OD2 . ASP B 1 347 ? -21.122 -12.545 0.797 1.00 32.39 ? 347 ASP B OD2 1 ATOM 6776 N N . ALA B 1 348 ? -17.795 -15.352 -2.778 1.00 30.25 ? 348 ALA B N 1 ATOM 6777 C CA . ALA B 1 348 ? -17.332 -16.025 -3.991 1.00 30.40 ? 348 ALA B CA 1 ATOM 6778 C C . ALA B 1 348 ? -16.938 -17.469 -3.679 1.00 30.48 ? 348 ALA B C 1 ATOM 6779 O O . ALA B 1 348 ? -17.310 -18.397 -4.402 1.00 30.23 ? 348 ALA B O 1 ATOM 6780 C CB . ALA B 1 348 ? -16.154 -15.265 -4.616 1.00 30.29 ? 348 ALA B CB 1 ATOM 6781 N N . LEU B 1 349 ? -16.184 -17.639 -2.592 1.00 30.78 ? 349 LEU B N 1 ATOM 6782 C CA . LEU B 1 349 ? -15.766 -18.955 -2.115 1.00 31.06 ? 349 LEU B CA 1 ATOM 6783 C C . LEU B 1 349 ? -16.950 -19.838 -1.699 1.00 31.37 ? 349 LEU B C 1 ATOM 6784 O O . LEU B 1 349 ? -16.990 -21.017 -2.041 1.00 31.22 ? 349 LEU B O 1 ATOM 6785 C CB . LEU B 1 349 ? -14.763 -18.805 -0.971 1.00 30.97 ? 349 LEU B CB 1 ATOM 6786 C CG . LEU B 1 349 ? -13.262 -19.026 -1.215 1.00 30.68 ? 349 LEU B CG 1 ATOM 6787 C CD1 . LEU B 1 349 ? -12.866 -19.230 -2.683 1.00 28.80 ? 349 LEU B CD1 1 ATOM 6788 C CD2 . LEU B 1 349 ? -12.458 -17.905 -0.559 1.00 29.73 ? 349 LEU B CD2 1 ATOM 6789 N N . MET B 1 350 ? -17.922 -19.256 -0.994 1.00 31.74 ? 350 MET B N 1 ATOM 6790 C CA . MET B 1 350 ? -19.142 -19.977 -0.613 1.00 32.15 ? 350 MET B CA 1 ATOM 6791 C C . MET B 1 350 ? -19.970 -20.426 -1.830 1.00 32.32 ? 350 MET B C 1 ATOM 6792 O O . MET B 1 350 ? -20.739 -21.388 -1.743 1.00 32.40 ? 350 MET B O 1 ATOM 6793 C CB . MET B 1 350 ? -20.008 -19.150 0.352 1.00 32.08 ? 350 MET B CB 1 ATOM 6794 C CG . MET B 1 350 ? -19.367 -18.809 1.701 1.00 32.93 ? 350 MET B CG 1 ATOM 6795 S SD . MET B 1 350 ? -18.677 -20.188 2.677 1.00 35.62 ? 350 MET B SD 1 ATOM 6796 C CE . MET B 1 350 ? -16.977 -20.265 2.106 1.00 34.38 ? 350 MET B CE 1 ATOM 6797 N N . LEU B 1 351 ? -19.813 -19.725 -2.952 1.00 32.37 ? 351 LEU B N 1 ATOM 6798 C CA . LEU B 1 351 ? -20.495 -20.094 -4.191 1.00 32.55 ? 351 LEU B CA 1 ATOM 6799 C C . LEU B 1 351 ? -19.643 -21.000 -5.102 1.00 32.88 ? 351 LEU B C 1 ATOM 6800 O O . LEU B 1 351 ? -19.968 -21.182 -6.279 1.00 32.79 ? 351 LEU B O 1 ATOM 6801 C CB . LEU B 1 351 ? -20.958 -18.847 -4.941 1.00 32.21 ? 351 LEU B CB 1 ATOM 6802 C CG . LEU B 1 351 ? -22.000 -17.953 -4.265 1.00 31.86 ? 351 LEU B CG 1 ATOM 6803 C CD1 . LEU B 1 351 ? -21.988 -16.578 -4.911 1.00 30.56 ? 351 LEU B CD1 1 ATOM 6804 C CD2 . LEU B 1 351 ? -23.400 -18.551 -4.316 1.00 31.09 ? 351 LEU B CD2 1 ATOM 6805 N N . ASN B 1 352 ? -18.569 -21.565 -4.543 1.00 33.33 ? 352 ASN B N 1 ATOM 6806 C CA . ASN B 1 352 ? -17.665 -22.491 -5.254 1.00 33.87 ? 352 ASN B CA 1 ATOM 6807 C C . ASN B 1 352 ? -17.005 -21.905 -6.498 1.00 32.83 ? 352 ASN B C 1 ATOM 6808 O O . ASN B 1 352 ? -16.900 -22.583 -7.516 1.00 32.81 ? 352 ASN B O 1 ATOM 6809 C CB . ASN B 1 352 ? -18.371 -23.810 -5.630 1.00 34.84 ? 352 ASN B CB 1 ATOM 6810 C CG . ASN B 1 352 ? -19.159 -24.416 -4.479 1.00 38.79 ? 352 ASN B CG 1 ATOM 6811 O OD1 . ASN B 1 352 ? -18.662 -24.530 -3.358 1.00 41.24 ? 352 ASN B OD1 1 ATOM 6812 N ND2 . ASN B 1 352 ? -20.405 -24.819 -4.767 1.00 44.65 ? 352 ASN B ND2 1 ATOM 6813 N N . THR B 1 353 ? -16.562 -20.652 -6.419 1.00 31.64 ? 353 THR B N 1 ATOM 6814 C CA . THR B 1 353 ? -15.854 -20.019 -7.532 1.00 30.29 ? 353 THR B CA 1 ATOM 6815 C C . THR B 1 353 ? -14.595 -20.832 -7.910 1.00 29.66 ? 353 THR B C 1 ATOM 6816 O O . THR B 1 353 ? -13.902 -21.372 -7.030 1.00 29.56 ? 353 THR B O 1 ATOM 6817 C CB . THR B 1 353 ? -15.533 -18.525 -7.232 1.00 30.16 ? 353 THR B CB 1 ATOM 6818 O OG1 . THR B 1 353 ? -15.274 -17.826 -8.450 1.00 30.24 ? 353 THR B OG1 1 ATOM 6819 C CG2 . THR B 1 353 ? -14.341 -18.366 -6.308 1.00 30.11 ? 353 THR B CG2 1 ATOM 6820 N N . THR B 1 354 ? -14.338 -20.950 -9.218 1.00 28.49 ? 354 THR B N 1 ATOM 6821 C CA . THR B 1 354 ? -13.163 -21.669 -9.729 1.00 27.14 ? 354 THR B CA 1 ATOM 6822 C C . THR B 1 354 ? -11.919 -20.815 -9.531 1.00 26.52 ? 354 THR B C 1 ATOM 6823 O O . THR B 1 354 ? -10.889 -21.313 -9.090 1.00 26.24 ? 354 THR B O 1 ATOM 6824 C CB . THR B 1 354 ? -13.320 -22.030 -11.223 1.00 27.06 ? 354 THR B CB 1 ATOM 6825 O OG1 . THR B 1 354 ? -14.464 -22.863 -11.392 1.00 26.90 ? 354 THR B OG1 1 ATOM 6826 C CG2 . THR B 1 354 ? -12.106 -22.757 -11.752 1.00 26.57 ? 354 THR B CG2 1 ATOM 6827 N N . ARG B 1 355 ? -12.029 -19.529 -9.871 1.00 25.81 ? 355 ARG B N 1 ATOM 6828 C CA . ARG B 1 355 ? -10.970 -18.550 -9.623 1.00 25.02 ? 355 ARG B CA 1 ATOM 6829 C C . ARG B 1 355 ? -11.564 -17.276 -9.006 1.00 24.58 ? 355 ARG B C 1 ATOM 6830 O O . ARG B 1 355 ? -12.762 -17.024 -9.152 1.00 24.52 ? 355 ARG B O 1 ATOM 6831 C CB . ARG B 1 355 ? -10.202 -18.222 -10.914 1.00 24.85 ? 355 ARG B CB 1 ATOM 6832 C CG . ARG B 1 355 ? -9.389 -19.379 -11.488 1.00 24.05 ? 355 ARG B CG 1 ATOM 6833 C CD . ARG B 1 355 ? -8.441 -18.953 -12.608 1.00 22.76 ? 355 ARG B CD 1 ATOM 6834 N NE . ARG B 1 355 ? -9.096 -18.210 -13.678 1.00 23.78 ? 355 ARG B NE 1 ATOM 6835 C CZ . ARG B 1 355 ? -9.519 -18.697 -14.836 1.00 23.78 ? 355 ARG B CZ 1 ATOM 6836 N NH1 . ARG B 1 355 ? -9.371 -19.918 -15.092 1.00 24.46 ? 355 ARG B NH1 1 ATOM 6837 N NH2 . ARG B 1 355 ? -10.089 -17.986 -15.767 1.00 23.17 ? 355 ARG B NH2 1 ATOM 6838 N N . ILE B 1 356 ? -10.723 -16.497 -8.318 1.00 23.76 ? 356 ILE B N 1 ATOM 6839 C CA . ILE B 1 356 ? -11.088 -15.173 -7.796 1.00 23.11 ? 356 ILE B CA 1 ATOM 6840 C C . ILE B 1 356 ? -10.393 -14.051 -8.602 1.00 23.19 ? 356 ILE B C 1 ATOM 6841 O O . ILE B 1 356 ? -9.154 -13.990 -8.677 1.00 23.46 ? 356 ILE B O 1 ATOM 6842 C CB . ILE B 1 356 ? -10.692 -15.028 -6.299 1.00 23.11 ? 356 ILE B CB 1 ATOM 6843 C CG1 . ILE B 1 356 ? -11.396 -16.082 -5.426 1.00 23.13 ? 356 ILE B CG1 1 ATOM 6844 C CG2 . ILE B 1 356 ? -10.958 -13.608 -5.785 1.00 22.01 ? 356 ILE B CG2 1 ATOM 6845 C CD1 . ILE B 1 356 ? -10.681 -16.380 -4.088 1.00 20.70 ? 356 ILE B CD1 1 ATOM 6846 N N . GLY B 1 357 ? -11.180 -13.158 -9.192 1.00 22.52 ? 357 GLY B N 1 ATOM 6847 C CA . GLY B 1 357 ? -10.629 -12.010 -9.901 1.00 21.87 ? 357 GLY B CA 1 ATOM 6848 C C . GLY B 1 357 ? -10.126 -10.941 -8.953 1.00 21.77 ? 357 GLY B C 1 ATOM 6849 O O . GLY B 1 357 ? -10.902 -10.381 -8.165 1.00 22.05 ? 357 GLY B O 1 ATOM 6850 N N . HIS B 1 358 ? -8.826 -10.662 -9.027 1.00 21.18 ? 358 HIS B N 1 ATOM 6851 C CA . HIS B 1 358 ? -8.166 -9.653 -8.190 1.00 20.76 ? 358 HIS B CA 1 ATOM 6852 C C . HIS B 1 358 ? -7.898 -10.111 -6.770 1.00 20.93 ? 358 HIS B C 1 ATOM 6853 O O . HIS B 1 358 ? -6.739 -10.244 -6.383 1.00 21.37 ? 358 HIS B O 1 ATOM 6854 C CB . HIS B 1 358 ? -8.930 -8.333 -8.181 1.00 20.53 ? 358 HIS B CB 1 ATOM 6855 C CG . HIS B 1 358 ? -9.068 -7.721 -9.531 1.00 19.73 ? 358 HIS B CG 1 ATOM 6856 N ND1 . HIS B 1 358 ? -8.030 -7.063 -10.152 1.00 18.28 ? 358 HIS B ND1 1 ATOM 6857 C CD2 . HIS B 1 358 ? -10.114 -7.677 -10.386 1.00 19.23 ? 358 HIS B CD2 1 ATOM 6858 C CE1 . HIS B 1 358 ? -8.436 -6.623 -11.328 1.00 19.30 ? 358 HIS B CE1 1 ATOM 6859 N NE2 . HIS B 1 358 ? -9.697 -6.983 -11.495 1.00 19.78 ? 358 HIS B NE2 1 ATOM 6860 N N . GLY B 1 359 ? -8.954 -10.350 -5.994 1.00 20.87 ? 359 GLY B N 1 ATOM 6861 C CA . GLY B 1 359 ? -8.800 -10.755 -4.595 1.00 20.86 ? 359 GLY B CA 1 ATOM 6862 C C . GLY B 1 359 ? -7.880 -9.837 -3.811 1.00 20.94 ? 359 GLY B C 1 ATOM 6863 O O . GLY B 1 359 ? -7.181 -10.282 -2.903 1.00 20.88 ? 359 GLY B O 1 ATOM 6864 N N . PHE B 1 360 ? -7.895 -8.552 -4.169 1.00 21.05 ? 360 PHE B N 1 ATOM 6865 C CA . PHE B 1 360 ? -7.002 -7.525 -3.617 1.00 20.96 ? 360 PHE B CA 1 ATOM 6866 C C . PHE B 1 360 ? -7.045 -7.441 -2.092 1.00 21.44 ? 360 PHE B C 1 ATOM 6867 O O . PHE B 1 360 ? -6.021 -7.214 -1.455 1.00 21.68 ? 360 PHE B O 1 ATOM 6868 C CB . PHE B 1 360 ? -7.376 -6.174 -4.226 1.00 20.59 ? 360 PHE B CB 1 ATOM 6869 C CG . PHE B 1 360 ? -6.428 -5.052 -3.905 1.00 19.44 ? 360 PHE B CG 1 ATOM 6870 C CD1 . PHE B 1 360 ? -6.660 -4.214 -2.817 1.00 18.48 ? 360 PHE B CD1 1 ATOM 6871 C CD2 . PHE B 1 360 ? -5.336 -4.793 -4.730 1.00 18.67 ? 360 PHE B CD2 1 ATOM 6872 C CE1 . PHE B 1 360 ? -5.810 -3.156 -2.531 1.00 17.11 ? 360 PHE B CE1 1 ATOM 6873 C CE2 . PHE B 1 360 ? -4.483 -3.726 -4.457 1.00 18.52 ? 360 PHE B CE2 1 ATOM 6874 C CZ . PHE B 1 360 ? -4.723 -2.903 -3.351 1.00 17.51 ? 360 PHE B CZ 1 ATOM 6875 N N . ALA B 1 361 ? -8.224 -7.621 -1.508 1.00 21.71 ? 361 ALA B N 1 ATOM 6876 C CA . ALA B 1 361 ? -8.372 -7.497 -0.065 1.00 21.99 ? 361 ALA B CA 1 ATOM 6877 C C . ALA B 1 361 ? -8.124 -8.813 0.689 1.00 22.33 ? 361 ALA B C 1 ATOM 6878 O O . ALA B 1 361 ? -8.392 -8.891 1.892 1.00 22.10 ? 361 ALA B O 1 ATOM 6879 C CB . ALA B 1 361 ? -9.759 -6.941 0.266 1.00 22.02 ? 361 ALA B CB 1 ATOM 6880 N N . LEU B 1 362 ? -7.607 -9.831 -0.005 1.00 22.60 ? 362 LEU B N 1 ATOM 6881 C CA . LEU B 1 362 ? -7.460 -11.172 0.585 1.00 23.53 ? 362 LEU B CA 1 ATOM 6882 C C . LEU B 1 362 ? -6.576 -11.245 1.833 1.00 23.99 ? 362 LEU B C 1 ATOM 6883 O O . LEU B 1 362 ? -6.965 -11.852 2.833 1.00 24.16 ? 362 LEU B O 1 ATOM 6884 C CB . LEU B 1 362 ? -6.942 -12.196 -0.430 1.00 23.52 ? 362 LEU B CB 1 ATOM 6885 C CG . LEU B 1 362 ? -7.548 -13.611 -0.443 1.00 23.23 ? 362 LEU B CG 1 ATOM 6886 C CD1 . LEU B 1 362 ? -6.505 -14.640 -0.895 1.00 21.83 ? 362 LEU B CD1 1 ATOM 6887 C CD2 . LEU B 1 362 ? -8.197 -14.027 0.872 1.00 21.40 ? 362 LEU B CD2 1 ATOM 6888 N N . SER B 1 363 ? -5.393 -10.642 1.766 1.00 24.30 ? 363 SER B N 1 ATOM 6889 C CA . SER B 1 363 ? -4.446 -10.675 2.879 1.00 24.79 ? 363 SER B CA 1 ATOM 6890 C C . SER B 1 363 ? -4.962 -9.997 4.156 1.00 25.30 ? 363 SER B C 1 ATOM 6891 O O . SER B 1 363 ? -4.324 -10.092 5.198 1.00 25.62 ? 363 SER B O 1 ATOM 6892 C CB . SER B 1 363 ? -3.123 -10.044 2.465 1.00 24.81 ? 363 SER B CB 1 ATOM 6893 O OG . SER B 1 363 ? -3.284 -8.659 2.205 1.00 24.68 ? 363 SER B OG 1 ATOM 6894 N N . LYS B 1 364 ? -6.096 -9.307 4.080 1.00 25.63 ? 364 LYS B N 1 ATOM 6895 C CA . LYS B 1 364 ? -6.680 -8.695 5.272 1.00 26.28 ? 364 LYS B CA 1 ATOM 6896 C C . LYS B 1 364 ? -7.654 -9.648 5.951 1.00 26.38 ? 364 LYS B C 1 ATOM 6897 O O . LYS B 1 364 ? -8.191 -9.346 7.007 1.00 26.52 ? 364 LYS B O 1 ATOM 6898 C CB . LYS B 1 364 ? -7.352 -7.355 4.942 1.00 26.42 ? 364 LYS B CB 1 ATOM 6899 C CG . LYS B 1 364 ? -6.353 -6.277 4.501 1.00 27.66 ? 364 LYS B CG 1 ATOM 6900 C CD . LYS B 1 364 ? -6.989 -4.913 4.392 1.00 28.70 ? 364 LYS B CD 1 ATOM 6901 C CE . LYS B 1 364 ? -6.155 -3.989 3.522 1.00 30.45 ? 364 LYS B CE 1 ATOM 6902 N NZ . LYS B 1 364 ? -6.131 -4.478 2.109 1.00 32.11 ? 364 LYS B NZ 1 ATOM 6903 N N . HIS B 1 365 ? -7.867 -10.805 5.335 1.00 26.61 ? 365 HIS B N 1 ATOM 6904 C CA . HIS B 1 365 ? -8.786 -11.815 5.853 1.00 26.81 ? 365 HIS B CA 1 ATOM 6905 C C . HIS B 1 365 ? -8.066 -13.160 5.974 1.00 26.67 ? 365 HIS B C 1 ATOM 6906 O O . HIS B 1 365 ? -8.150 -13.995 5.070 1.00 26.56 ? 365 HIS B O 1 ATOM 6907 C CB . HIS B 1 365 ? -10.018 -11.940 4.948 1.00 26.82 ? 365 HIS B CB 1 ATOM 6908 C CG . HIS B 1 365 ? -10.903 -10.736 4.962 1.00 27.74 ? 365 HIS B CG 1 ATOM 6909 N ND1 . HIS B 1 365 ? -10.799 -9.725 4.030 1.00 29.32 ? 365 HIS B ND1 1 ATOM 6910 C CD2 . HIS B 1 365 ? -11.902 -10.373 5.801 1.00 28.16 ? 365 HIS B CD2 1 ATOM 6911 C CE1 . HIS B 1 365 ? -11.705 -8.798 4.289 1.00 30.00 ? 365 HIS B CE1 1 ATOM 6912 N NE2 . HIS B 1 365 ? -12.386 -9.166 5.360 1.00 28.81 ? 365 HIS B NE2 1 ATOM 6913 N N . PRO B 1 366 ? -7.352 -13.370 7.094 1.00 26.79 ? 366 PRO B N 1 ATOM 6914 C CA . PRO B 1 366 ? -6.517 -14.564 7.270 1.00 26.84 ? 366 PRO B CA 1 ATOM 6915 C C . PRO B 1 366 ? -7.273 -15.888 7.129 1.00 26.90 ? 366 PRO B C 1 ATOM 6916 O O . PRO B 1 366 ? -6.737 -16.819 6.535 1.00 27.05 ? 366 PRO B O 1 ATOM 6917 C CB . PRO B 1 366 ? -5.948 -14.399 8.687 1.00 26.79 ? 366 PRO B CB 1 ATOM 6918 C CG . PRO B 1 366 ? -6.838 -13.399 9.354 1.00 26.97 ? 366 PRO B CG 1 ATOM 6919 C CD . PRO B 1 366 ? -7.313 -12.492 8.279 1.00 26.76 ? 366 PRO B CD 1 ATOM 6920 N N . ALA B 1 367 ? -8.503 -15.956 7.644 1.00 27.04 ? 367 ALA B N 1 ATOM 6921 C CA . ALA B 1 367 ? -9.323 -17.179 7.594 1.00 27.31 ? 367 ALA B CA 1 ATOM 6922 C C . ALA B 1 367 ? -9.771 -17.547 6.180 1.00 27.74 ? 367 ALA B C 1 ATOM 6923 O O . ALA B 1 367 ? -9.705 -18.718 5.791 1.00 27.49 ? 367 ALA B O 1 ATOM 6924 C CB . ALA B 1 367 ? -10.535 -17.059 8.521 1.00 27.09 ? 367 ALA B CB 1 ATOM 6925 N N . VAL B 1 368 ? -10.230 -16.543 5.429 1.00 28.12 ? 368 VAL B N 1 ATOM 6926 C CA . VAL B 1 368 ? -10.592 -16.702 4.026 1.00 28.75 ? 368 VAL B CA 1 ATOM 6927 C C . VAL B 1 368 ? -9.347 -17.073 3.200 1.00 29.35 ? 368 VAL B C 1 ATOM 6928 O O . VAL B 1 368 ? -9.410 -17.925 2.310 1.00 29.31 ? 368 VAL B O 1 ATOM 6929 C CB . VAL B 1 368 ? -11.254 -15.408 3.476 1.00 28.84 ? 368 VAL B CB 1 ATOM 6930 C CG1 . VAL B 1 368 ? -11.714 -15.590 2.043 1.00 28.53 ? 368 VAL B CG1 1 ATOM 6931 C CG2 . VAL B 1 368 ? -12.427 -14.998 4.348 1.00 28.38 ? 368 VAL B CG2 1 ATOM 6932 N N . ARG B 1 369 ? -8.220 -16.440 3.520 1.00 29.96 ? 369 ARG B N 1 ATOM 6933 C CA . ARG B 1 369 ? -6.937 -16.754 2.894 1.00 30.93 ? 369 ARG B CA 1 ATOM 6934 C C . ARG B 1 369 ? -6.587 -18.233 3.055 1.00 31.18 ? 369 ARG B C 1 ATOM 6935 O O . ARG B 1 369 ? -6.278 -18.906 2.070 1.00 31.04 ? 369 ARG B O 1 ATOM 6936 C CB . ARG B 1 369 ? -5.837 -15.864 3.473 1.00 31.14 ? 369 ARG B CB 1 ATOM 6937 C CG . ARG B 1 369 ? -4.458 -16.046 2.870 1.00 32.66 ? 369 ARG B CG 1 ATOM 6938 C CD . ARG B 1 369 ? -3.442 -15.294 3.713 1.00 35.97 ? 369 ARG B CD 1 ATOM 6939 N NE . ARG B 1 369 ? -2.065 -15.503 3.270 1.00 38.80 ? 369 ARG B NE 1 ATOM 6940 C CZ . ARG B 1 369 ? -1.043 -14.723 3.614 1.00 40.32 ? 369 ARG B CZ 1 ATOM 6941 N NH1 . ARG B 1 369 ? -1.239 -13.671 4.398 1.00 40.53 ? 369 ARG B NH1 1 ATOM 6942 N NH2 . ARG B 1 369 ? 0.175 -14.986 3.163 1.00 40.97 ? 369 ARG B NH2 1 ATOM 6943 N N . THR B 1 370 ? -6.657 -18.726 4.291 1.00 31.60 ? 370 THR B N 1 ATOM 6944 C CA . THR B 1 370 ? -6.404 -20.138 4.600 1.00 32.27 ? 370 THR B CA 1 ATOM 6945 C C . THR B 1 370 ? -7.357 -21.069 3.853 1.00 32.69 ? 370 THR B C 1 ATOM 6946 O O . THR B 1 370 ? -6.927 -22.071 3.289 1.00 32.81 ? 370 THR B O 1 ATOM 6947 C CB . THR B 1 370 ? -6.501 -20.399 6.124 1.00 32.31 ? 370 THR B CB 1 ATOM 6948 O OG1 . THR B 1 370 ? -5.502 -19.635 6.800 1.00 31.99 ? 370 THR B OG1 1 ATOM 6949 C CG2 . THR B 1 370 ? -6.303 -21.872 6.456 1.00 32.08 ? 370 THR B CG2 1 ATOM 6950 N N . TYR B 1 371 ? -8.645 -20.722 3.850 1.00 33.37 ? 371 TYR B N 1 ATOM 6951 C CA . TYR B 1 371 ? -9.678 -21.519 3.191 1.00 34.05 ? 371 TYR B CA 1 ATOM 6952 C C . TYR B 1 371 ? -9.454 -21.638 1.687 1.00 34.54 ? 371 TYR B C 1 ATOM 6953 O O . TYR B 1 371 ? -9.562 -22.729 1.125 1.00 34.64 ? 371 TYR B O 1 ATOM 6954 C CB . TYR B 1 371 ? -11.060 -20.927 3.470 1.00 34.22 ? 371 TYR B CB 1 ATOM 6955 C CG . TYR B 1 371 ? -12.217 -21.715 2.889 1.00 34.68 ? 371 TYR B CG 1 ATOM 6956 C CD1 . TYR B 1 371 ? -12.821 -21.324 1.696 1.00 34.97 ? 371 TYR B CD1 1 ATOM 6957 C CD2 . TYR B 1 371 ? -12.714 -22.843 3.542 1.00 35.36 ? 371 TYR B CD2 1 ATOM 6958 C CE1 . TYR B 1 371 ? -13.884 -22.037 1.167 1.00 35.37 ? 371 TYR B CE1 1 ATOM 6959 C CE2 . TYR B 1 371 ? -13.779 -23.563 3.021 1.00 35.45 ? 371 TYR B CE2 1 ATOM 6960 C CZ . TYR B 1 371 ? -14.357 -23.156 1.835 1.00 35.94 ? 371 TYR B CZ 1 ATOM 6961 O OH . TYR B 1 371 ? -15.409 -23.873 1.310 1.00 36.47 ? 371 TYR B OH 1 ATOM 6962 N N . SER B 1 372 ? -9.153 -20.512 1.046 1.00 35.26 ? 372 SER B N 1 ATOM 6963 C CA . SER B 1 372 ? -8.900 -20.471 -0.394 1.00 36.07 ? 372 SER B CA 1 ATOM 6964 C C . SER B 1 372 ? -7.651 -21.281 -0.780 1.00 36.65 ? 372 SER B C 1 ATOM 6965 O O . SER B 1 372 ? -7.635 -21.997 -1.793 1.00 36.49 ? 372 SER B O 1 ATOM 6966 C CB . SER B 1 372 ? -8.835 -19.012 -0.872 1.00 35.77 ? 372 SER B CB 1 ATOM 6967 O OG . SER B 1 372 ? -7.608 -18.699 -1.497 1.00 36.02 ? 372 SER B OG 1 ATOM 6968 N N . TRP B 1 373 ? -6.621 -21.171 0.052 1.00 37.46 ? 373 TRP B N 1 ATOM 6969 C CA . TRP B 1 373 ? -5.394 -21.940 -0.107 1.00 38.49 ? 373 TRP B CA 1 ATOM 6970 C C . TRP B 1 373 ? -5.687 -23.437 0.023 1.00 38.37 ? 373 TRP B C 1 ATOM 6971 O O . TRP B 1 373 ? -5.222 -24.236 -0.791 1.00 38.13 ? 373 TRP B O 1 ATOM 6972 C CB . TRP B 1 373 ? -4.375 -21.482 0.932 1.00 38.94 ? 373 TRP B CB 1 ATOM 6973 C CG . TRP B 1 373 ? -3.091 -22.224 0.927 1.00 41.82 ? 373 TRP B CG 1 ATOM 6974 C CD1 . TRP B 1 373 ? -2.003 -21.979 0.143 1.00 43.53 ? 373 TRP B CD1 1 ATOM 6975 C CD2 . TRP B 1 373 ? -2.743 -23.331 1.765 1.00 44.73 ? 373 TRP B CD2 1 ATOM 6976 N NE1 . TRP B 1 373 ? -0.997 -22.870 0.434 1.00 44.95 ? 373 TRP B NE1 1 ATOM 6977 C CE2 . TRP B 1 373 ? -1.426 -23.712 1.427 1.00 45.51 ? 373 TRP B CE2 1 ATOM 6978 C CE3 . TRP B 1 373 ? -3.416 -24.037 2.773 1.00 45.59 ? 373 TRP B CE3 1 ATOM 6979 C CZ2 . TRP B 1 373 ? -0.763 -24.771 2.064 1.00 46.89 ? 373 TRP B CZ2 1 ATOM 6980 C CZ3 . TRP B 1 373 ? -2.759 -25.091 3.407 1.00 46.88 ? 373 TRP B CZ3 1 ATOM 6981 C CH2 . TRP B 1 373 ? -1.444 -25.447 3.050 1.00 46.92 ? 373 TRP B CH2 1 ATOM 6982 N N . LYS B 1 374 ? -6.487 -23.799 1.027 1.00 38.24 ? 374 LYS B N 1 ATOM 6983 C CA . LYS B 1 374 ? -6.894 -25.186 1.246 1.00 38.23 ? 374 LYS B CA 1 ATOM 6984 C C . LYS B 1 374 ? -7.756 -25.785 0.129 1.00 37.68 ? 374 LYS B C 1 ATOM 6985 O O . LYS B 1 374 ? -7.559 -26.937 -0.235 1.00 37.86 ? 374 LYS B O 1 ATOM 6986 C CB . LYS B 1 374 ? -7.557 -25.357 2.620 1.00 38.58 ? 374 LYS B CB 1 ATOM 6987 C CG . LYS B 1 374 ? -6.532 -25.582 3.720 1.00 40.37 ? 374 LYS B CG 1 ATOM 6988 C CD . LYS B 1 374 ? -7.118 -25.677 5.119 1.00 42.18 ? 374 LYS B CD 1 ATOM 6989 C CE . LYS B 1 374 ? -5.984 -25.954 6.119 1.00 43.78 ? 374 LYS B CE 1 ATOM 6990 N NZ . LYS B 1 374 ? -6.409 -25.882 7.548 1.00 45.08 ? 374 LYS B NZ 1 ATOM 6991 N N . LYS B 1 375 ? -8.697 -25.014 -0.417 1.00 36.97 ? 375 LYS B N 1 ATOM 6992 C CA . LYS B 1 375 ? -9.496 -25.472 -1.568 1.00 36.14 ? 375 LYS B CA 1 ATOM 6993 C C . LYS B 1 375 ? -8.778 -25.253 -2.914 1.00 34.78 ? 375 LYS B C 1 ATOM 6994 O O . LYS B 1 375 ? -9.370 -25.441 -3.977 1.00 34.45 ? 375 LYS B O 1 ATOM 6995 C CB . LYS B 1 375 ? -10.873 -24.788 -1.590 1.00 36.60 ? 375 LYS B CB 1 ATOM 6996 C CG . LYS B 1 375 ? -11.800 -25.169 -0.456 1.00 38.67 ? 375 LYS B CG 1 ATOM 6997 C CD . LYS B 1 375 ? -12.304 -26.600 -0.593 1.00 43.22 ? 375 LYS B CD 1 ATOM 6998 C CE . LYS B 1 375 ? -13.067 -27.046 0.652 1.00 45.68 ? 375 LYS B CE 1 ATOM 6999 N NZ . LYS B 1 375 ? -13.253 -28.529 0.697 1.00 46.97 ? 375 LYS B NZ 1 ATOM 7000 N N . ASP B 1 376 ? -7.505 -24.861 -2.844 1.00 33.36 ? 376 ASP B N 1 ATOM 7001 C CA . ASP B 1 376 ? -6.681 -24.503 -4.008 1.00 32.10 ? 376 ASP B CA 1 ATOM 7002 C C . ASP B 1 376 ? -7.369 -23.570 -5.037 1.00 30.82 ? 376 ASP B C 1 ATOM 7003 O O . ASP B 1 376 ? -7.319 -23.806 -6.245 1.00 30.74 ? 376 ASP B O 1 ATOM 7004 C CB . ASP B 1 376 ? -6.085 -25.754 -4.678 1.00 32.26 ? 376 ASP B CB 1 ATOM 7005 C CG . ASP B 1 376 ? -4.805 -25.450 -5.459 1.00 32.95 ? 376 ASP B CG 1 ATOM 7006 O OD1 . ASP B 1 376 ? -4.170 -24.397 -5.211 1.00 33.28 ? 376 ASP B OD1 1 ATOM 7007 O OD2 . ASP B 1 376 ? -4.427 -26.269 -6.319 1.00 34.13 ? 376 ASP B OD2 1 ATOM 7008 N N . ILE B 1 377 ? -7.999 -22.508 -4.545 1.00 29.19 ? 377 ILE B N 1 ATOM 7009 C CA . ILE B 1 377 ? -8.661 -21.546 -5.417 1.00 27.75 ? 377 ILE B CA 1 ATOM 7010 C C . ILE B 1 377 ? -7.765 -20.314 -5.585 1.00 26.72 ? 377 ILE B C 1 ATOM 7011 O O . ILE B 1 377 ? -7.553 -19.577 -4.625 1.00 26.59 ? 377 ILE B O 1 ATOM 7012 C CB . ILE B 1 377 ? -10.068 -21.145 -4.874 1.00 27.88 ? 377 ILE B CB 1 ATOM 7013 C CG1 . ILE B 1 377 ? -10.937 -22.390 -4.592 1.00 27.54 ? 377 ILE B CG1 1 ATOM 7014 C CG2 . ILE B 1 377 ? -10.763 -20.123 -5.802 1.00 27.28 ? 377 ILE B CG2 1 ATOM 7015 C CD1 . ILE B 1 377 ? -11.207 -23.282 -5.794 1.00 27.58 ? 377 ILE B CD1 1 ATOM 7016 N N . PRO B 1 378 ? -7.243 -20.091 -6.809 1.00 25.62 ? 378 PRO B N 1 ATOM 7017 C CA . PRO B 1 378 ? -6.269 -19.027 -7.049 1.00 25.23 ? 378 PRO B CA 1 ATOM 7018 C C . PRO B 1 378 ? -6.886 -17.629 -7.193 1.00 24.73 ? 378 PRO B C 1 ATOM 7019 O O . PRO B 1 378 ? -8.061 -17.492 -7.568 1.00 25.07 ? 378 PRO B O 1 ATOM 7020 C CB . PRO B 1 378 ? -5.627 -19.451 -8.380 1.00 24.83 ? 378 PRO B CB 1 ATOM 7021 C CG . PRO B 1 378 ? -6.709 -20.159 -9.093 1.00 24.75 ? 378 PRO B CG 1 ATOM 7022 C CD . PRO B 1 378 ? -7.559 -20.827 -8.049 1.00 25.27 ? 378 PRO B CD 1 ATOM 7023 N N . ILE B 1 379 ? -6.088 -16.602 -6.918 1.00 23.87 ? 379 ILE B N 1 ATOM 7024 C CA . ILE B 1 379 ? -6.464 -15.241 -7.301 1.00 22.95 ? 379 ILE B CA 1 ATOM 7025 C C . ILE B 1 379 ? -5.806 -14.843 -8.629 1.00 22.72 ? 379 ILE B C 1 ATOM 7026 O O . ILE B 1 379 ? -4.689 -15.255 -8.931 1.00 22.43 ? 379 ILE B O 1 ATOM 7027 C CB . ILE B 1 379 ? -6.148 -14.189 -6.194 1.00 22.97 ? 379 ILE B CB 1 ATOM 7028 C CG1 . ILE B 1 379 ? -4.680 -14.244 -5.763 1.00 22.10 ? 379 ILE B CG1 1 ATOM 7029 C CG2 . ILE B 1 379 ? -7.093 -14.354 -5.002 1.00 22.46 ? 379 ILE B CG2 1 ATOM 7030 C CD1 . ILE B 1 379 ? -4.220 -13.017 -5.026 1.00 21.64 ? 379 ILE B CD1 1 ATOM 7031 N N . GLU B 1 380 ? -6.521 -14.050 -9.422 1.00 22.74 ? 380 GLU B N 1 ATOM 7032 C CA . GLU B 1 380 ? -5.999 -13.499 -10.672 1.00 22.70 ? 380 GLU B CA 1 ATOM 7033 C C . GLU B 1 380 ? -5.521 -12.076 -10.399 1.00 22.84 ? 380 GLU B C 1 ATOM 7034 O O . GLU B 1 380 ? -6.335 -11.151 -10.265 1.00 22.90 ? 380 GLU B O 1 ATOM 7035 C CB . GLU B 1 380 ? -7.091 -13.483 -11.751 1.00 22.53 ? 380 GLU B CB 1 ATOM 7036 C CG . GLU B 1 380 ? -7.715 -14.850 -12.083 1.00 22.82 ? 380 GLU B CG 1 ATOM 7037 C CD . GLU B 1 380 ? -9.091 -14.722 -12.725 1.00 23.31 ? 380 GLU B CD 1 ATOM 7038 O OE1 . GLU B 1 380 ? -9.807 -13.751 -12.423 1.00 24.87 ? 380 GLU B OE1 1 ATOM 7039 O OE2 . GLU B 1 380 ? -9.467 -15.585 -13.531 1.00 22.23 ? 380 GLU B OE2 1 ATOM 7040 N N . VAL B 1 381 ? -4.205 -11.900 -10.302 1.00 22.78 ? 381 VAL B N 1 ATOM 7041 C CA . VAL B 1 381 ? -3.642 -10.584 -9.977 1.00 22.72 ? 381 VAL B CA 1 ATOM 7042 C C . VAL B 1 381 ? -3.255 -9.790 -11.221 1.00 22.92 ? 381 VAL B C 1 ATOM 7043 O O . VAL B 1 381 ? -2.565 -10.304 -12.105 1.00 22.99 ? 381 VAL B O 1 ATOM 7044 C CB . VAL B 1 381 ? -2.526 -10.643 -8.853 1.00 22.71 ? 381 VAL B CB 1 ATOM 7045 C CG1 . VAL B 1 381 ? -2.077 -12.071 -8.564 1.00 22.25 ? 381 VAL B CG1 1 ATOM 7046 C CG2 . VAL B 1 381 ? -1.351 -9.703 -9.129 1.00 21.93 ? 381 VAL B CG2 1 ATOM 7047 N N . CYS B 1 382 ? -3.742 -8.548 -11.274 1.00 23.36 ? 382 CYS B N 1 ATOM 7048 C CA . CYS B 1 382 ? -3.566 -7.634 -12.404 1.00 23.85 ? 382 CYS B CA 1 ATOM 7049 C C . CYS B 1 382 ? -2.974 -6.320 -11.902 1.00 23.96 ? 382 CYS B C 1 ATOM 7050 O O . CYS B 1 382 ? -3.723 -5.361 -11.635 1.00 24.34 ? 382 CYS B O 1 ATOM 7051 C CB . CYS B 1 382 ? -4.915 -7.348 -13.059 1.00 23.95 ? 382 CYS B CB 1 ATOM 7052 S SG . CYS B 1 382 ? -5.762 -8.783 -13.679 1.00 26.14 ? 382 CYS B SG 1 ATOM 7053 N N . PRO B 1 383 ? -1.632 -6.263 -11.767 1.00 23.76 ? 383 PRO B N 1 ATOM 7054 C CA . PRO B 1 383 ? -0.981 -5.137 -11.093 1.00 23.30 ? 383 PRO B CA 1 ATOM 7055 C C . PRO B 1 383 ? -1.193 -3.769 -11.750 1.00 22.84 ? 383 PRO B C 1 ATOM 7056 O O . PRO B 1 383 ? -1.454 -2.803 -11.038 1.00 22.99 ? 383 PRO B O 1 ATOM 7057 C CB . PRO B 1 383 ? 0.509 -5.528 -11.091 1.00 23.53 ? 383 PRO B CB 1 ATOM 7058 C CG . PRO B 1 383 ? 0.655 -6.533 -12.170 1.00 23.74 ? 383 PRO B CG 1 ATOM 7059 C CD . PRO B 1 383 ? -0.654 -7.266 -12.235 1.00 23.77 ? 383 PRO B CD 1 ATOM 7060 N N . ILE B 1 384 ? -1.080 -3.678 -13.073 1.00 22.33 ? 384 ILE B N 1 ATOM 7061 C CA . ILE B 1 384 ? -1.220 -2.391 -13.754 1.00 21.83 ? 384 ILE B CA 1 ATOM 7062 C C . ILE B 1 384 ? -2.635 -1.826 -13.590 1.00 21.87 ? 384 ILE B C 1 ATOM 7063 O O . ILE B 1 384 ? -2.816 -0.638 -13.305 1.00 22.06 ? 384 ILE B O 1 ATOM 7064 C CB . ILE B 1 384 ? -0.806 -2.473 -15.240 1.00 21.67 ? 384 ILE B CB 1 ATOM 7065 C CG1 . ILE B 1 384 ? 0.702 -2.710 -15.339 1.00 21.40 ? 384 ILE B CG1 1 ATOM 7066 C CG2 . ILE B 1 384 ? -1.185 -1.190 -15.989 1.00 21.12 ? 384 ILE B CG2 1 ATOM 7067 C CD1 . ILE B 1 384 ? 1.226 -2.923 -16.731 1.00 20.37 ? 384 ILE B CD1 1 ATOM 7068 N N . SER B 1 385 ? -3.629 -2.690 -13.739 1.00 21.76 ? 385 SER B N 1 ATOM 7069 C CA . SER B 1 385 ? -5.022 -2.312 -13.514 1.00 21.66 ? 385 SER B CA 1 ATOM 7070 C C . SER B 1 385 ? -5.252 -1.718 -12.129 1.00 21.40 ? 385 SER B C 1 ATOM 7071 O O . SER B 1 385 ? -5.889 -0.677 -12.013 1.00 21.86 ? 385 SER B O 1 ATOM 7072 C CB . SER B 1 385 ? -5.944 -3.512 -13.724 1.00 21.65 ? 385 SER B CB 1 ATOM 7073 O OG . SER B 1 385 ? -7.284 -3.162 -13.415 1.00 22.37 ? 385 SER B OG 1 ATOM 7074 N N . ASN B 1 386 ? -4.736 -2.378 -11.092 1.00 20.97 ? 386 ASN B N 1 ATOM 7075 C CA . ASN B 1 386 ? -4.877 -1.916 -9.708 1.00 20.59 ? 386 ASN B CA 1 ATOM 7076 C C . ASN B 1 386 ? -4.268 -0.527 -9.463 1.00 20.55 ? 386 ASN B C 1 ATOM 7077 O O . ASN B 1 386 ? -4.803 0.269 -8.681 1.00 20.18 ? 386 ASN B O 1 ATOM 7078 C CB . ASN B 1 386 ? -4.272 -2.934 -8.725 1.00 20.55 ? 386 ASN B CB 1 ATOM 7079 C CG . ASN B 1 386 ? -4.976 -4.306 -8.752 1.00 20.67 ? 386 ASN B CG 1 ATOM 7080 O OD1 . ASN B 1 386 ? -4.413 -5.302 -8.283 1.00 19.78 ? 386 ASN B OD1 1 ATOM 7081 N ND2 . ASN B 1 386 ? -6.202 -4.359 -9.285 1.00 18.75 ? 386 ASN B ND2 1 ATOM 7082 N N . GLN B 1 387 ? -3.153 -0.242 -10.137 1.00 20.26 ? 387 GLN B N 1 ATOM 7083 C CA . GLN B 1 387 ? -2.495 1.065 -10.041 1.00 20.02 ? 387 GLN B CA 1 ATOM 7084 C C . GLN B 1 387 ? -3.265 2.138 -10.794 1.00 20.01 ? 387 GLN B C 1 ATOM 7085 O O . GLN B 1 387 ? -3.523 3.220 -10.262 1.00 19.95 ? 387 GLN B O 1 ATOM 7086 C CB . GLN B 1 387 ? -1.068 0.993 -10.590 1.00 20.20 ? 387 GLN B CB 1 ATOM 7087 C CG . GLN B 1 387 ? -0.208 2.221 -10.296 1.00 19.16 ? 387 GLN B CG 1 ATOM 7088 C CD . GLN B 1 387 ? 1.212 2.041 -10.788 1.00 18.40 ? 387 GLN B CD 1 ATOM 7089 O OE1 . GLN B 1 387 ? 1.435 1.883 -11.987 1.00 18.17 ? 387 GLN B OE1 1 ATOM 7090 N NE2 . GLN B 1 387 ? 2.186 2.054 -9.863 1.00 16.54 ? 387 GLN B NE2 1 ATOM 7091 N N . VAL B 1 388 ? -3.616 1.834 -12.041 1.00 19.99 ? 388 VAL B N 1 ATOM 7092 C CA . VAL B 1 388 ? -4.325 2.789 -12.894 1.00 19.93 ? 388 VAL B CA 1 ATOM 7093 C C . VAL B 1 388 ? -5.681 3.134 -12.285 1.00 19.75 ? 388 VAL B C 1 ATOM 7094 O O . VAL B 1 388 ? -6.070 4.301 -12.270 1.00 19.43 ? 388 VAL B O 1 ATOM 7095 C CB . VAL B 1 388 ? -4.446 2.286 -14.368 1.00 20.03 ? 388 VAL B CB 1 ATOM 7096 C CG1 . VAL B 1 388 ? -5.339 3.205 -15.197 1.00 20.13 ? 388 VAL B CG1 1 ATOM 7097 C CG2 . VAL B 1 388 ? -3.069 2.215 -15.013 1.00 20.11 ? 388 VAL B CG2 1 ATOM 7098 N N . LEU B 1 389 ? -6.367 2.121 -11.749 1.00 19.71 ? 389 LEU B N 1 ATOM 7099 C CA . LEU B 1 389 ? -7.686 2.320 -11.134 1.00 19.52 ? 389 LEU B CA 1 ATOM 7100 C C . LEU B 1 389 ? -7.609 2.777 -9.672 1.00 19.52 ? 389 LEU B C 1 ATOM 7101 O O . LEU B 1 389 ? -8.626 2.837 -8.971 1.00 19.66 ? 389 LEU B O 1 ATOM 7102 C CB . LEU B 1 389 ? -8.570 1.081 -11.307 1.00 19.19 ? 389 LEU B CB 1 ATOM 7103 C CG . LEU B 1 389 ? -8.908 0.720 -12.764 1.00 19.43 ? 389 LEU B CG 1 ATOM 7104 C CD1 . LEU B 1 389 ? -9.800 -0.517 -12.830 1.00 18.16 ? 389 LEU B CD1 1 ATOM 7105 C CD2 . LEU B 1 389 ? -9.545 1.888 -13.543 1.00 18.48 ? 389 LEU B CD2 1 ATOM 7106 N N . LYS B 1 390 ? -6.388 3.085 -9.236 1.00 19.43 ? 390 LYS B N 1 ATOM 7107 C CA . LYS B 1 390 ? -6.117 3.840 -8.006 1.00 19.44 ? 390 LYS B CA 1 ATOM 7108 C C . LYS B 1 390 ? -6.345 3.082 -6.687 1.00 19.46 ? 390 LYS B C 1 ATOM 7109 O O . LYS B 1 390 ? -6.553 3.696 -5.634 1.00 19.68 ? 390 LYS B O 1 ATOM 7110 C CB . LYS B 1 390 ? -6.851 5.197 -8.027 1.00 19.43 ? 390 LYS B CB 1 ATOM 7111 C CG . LYS B 1 390 ? -6.435 6.124 -9.195 1.00 19.63 ? 390 LYS B CG 1 ATOM 7112 C CD . LYS B 1 390 ? -7.333 7.345 -9.332 1.00 20.11 ? 390 LYS B CD 1 ATOM 7113 C CE . LYS B 1 390 ? -7.276 8.243 -8.108 1.00 21.20 ? 390 LYS B CE 1 ATOM 7114 N NZ . LYS B 1 390 ? -5.920 8.829 -7.924 1.00 22.30 ? 390 LYS B NZ 1 ATOM 7115 N N . LEU B 1 391 ? -6.297 1.751 -6.750 1.00 19.23 ? 391 LEU B N 1 ATOM 7116 C CA . LEU B 1 391 ? -6.269 0.911 -5.545 1.00 19.11 ? 391 LEU B CA 1 ATOM 7117 C C . LEU B 1 391 ? -4.947 1.024 -4.777 1.00 19.28 ? 391 LEU B C 1 ATOM 7118 O O . LEU B 1 391 ? -4.918 0.844 -3.562 1.00 19.25 ? 391 LEU B O 1 ATOM 7119 C CB . LEU B 1 391 ? -6.543 -0.551 -5.890 1.00 18.74 ? 391 LEU B CB 1 ATOM 7120 C CG . LEU B 1 391 ? -7.962 -1.149 -5.886 1.00 18.53 ? 391 LEU B CG 1 ATOM 7121 C CD1 . LEU B 1 391 ? -9.100 -0.133 -5.753 1.00 15.97 ? 391 LEU B CD1 1 ATOM 7122 C CD2 . LEU B 1 391 ? -8.155 -2.008 -7.128 1.00 17.56 ? 391 LEU B CD2 1 ATOM 7123 N N . VAL B 1 392 ? -3.869 1.346 -5.481 1.00 19.57 ? 392 VAL B N 1 ATOM 7124 C CA . VAL B 1 392 ? -2.541 1.425 -4.869 1.00 20.40 ? 392 VAL B CA 1 ATOM 7125 C C . VAL B 1 392 ? -1.596 2.274 -5.736 1.00 21.16 ? 392 VAL B C 1 ATOM 7126 O O . VAL B 1 392 ? -1.545 2.096 -6.957 1.00 21.35 ? 392 VAL B O 1 ATOM 7127 C CB . VAL B 1 392 ? -1.961 -0.006 -4.586 1.00 20.20 ? 392 VAL B CB 1 ATOM 7128 C CG1 . VAL B 1 392 ? -1.607 -0.717 -5.879 1.00 20.04 ? 392 VAL B CG1 1 ATOM 7129 C CG2 . VAL B 1 392 ? -0.778 0.061 -3.653 1.00 19.42 ? 392 VAL B CG2 1 ATOM 7130 N N . SER B 1 393 ? -0.875 3.204 -5.105 1.00 21.91 ? 393 SER B N 1 ATOM 7131 C CA . SER B 1 393 ? 0.028 4.107 -5.823 1.00 22.94 ? 393 SER B CA 1 ATOM 7132 C C . SER B 1 393 ? 1.309 3.421 -6.253 1.00 23.26 ? 393 SER B C 1 ATOM 7133 O O . SER B 1 393 ? 1.602 3.336 -7.439 1.00 23.72 ? 393 SER B O 1 ATOM 7134 C CB . SER B 1 393 ? 0.392 5.314 -4.962 1.00 23.06 ? 393 SER B CB 1 ATOM 7135 O OG . SER B 1 393 ? -0.530 6.361 -5.158 1.00 24.90 ? 393 SER B OG 1 ATOM 7136 N N . ASP B 1 394 ? 2.057 2.950 -5.258 1.00 23.56 ? 394 ASP B N 1 ATOM 7137 C CA . ASP B 1 394 ? 3.371 2.363 -5.395 1.00 23.59 ? 394 ASP B CA 1 ATOM 7138 C C . ASP B 1 394 ? 3.153 0.859 -5.327 1.00 23.46 ? 394 ASP B C 1 ATOM 7139 O O . ASP B 1 394 ? 2.720 0.345 -4.296 1.00 23.84 ? 394 ASP B O 1 ATOM 7140 C CB . ASP B 1 394 ? 4.203 2.863 -4.207 1.00 23.91 ? 394 ASP B CB 1 ATOM 7141 C CG . ASP B 1 394 ? 5.644 2.331 -4.175 1.00 25.20 ? 394 ASP B CG 1 ATOM 7142 O OD1 . ASP B 1 394 ? 5.988 1.372 -4.903 1.00 25.48 ? 394 ASP B OD1 1 ATOM 7143 O OD2 . ASP B 1 394 ? 6.433 2.887 -3.361 1.00 25.50 ? 394 ASP B OD2 1 ATOM 7144 N N . LEU B 1 395 ? 3.445 0.149 -6.418 1.00 23.19 ? 395 LEU B N 1 ATOM 7145 C CA . LEU B 1 395 ? 3.212 -1.304 -6.478 1.00 22.44 ? 395 LEU B CA 1 ATOM 7146 C C . LEU B 1 395 ? 4.099 -2.127 -5.540 1.00 22.58 ? 395 LEU B C 1 ATOM 7147 O O . LEU B 1 395 ? 3.832 -3.319 -5.304 1.00 22.76 ? 395 LEU B O 1 ATOM 7148 C CB . LEU B 1 395 ? 3.295 -1.826 -7.909 1.00 22.09 ? 395 LEU B CB 1 ATOM 7149 C CG . LEU B 1 395 ? 2.122 -1.451 -8.817 1.00 21.35 ? 395 LEU B CG 1 ATOM 7150 C CD1 . LEU B 1 395 ? 2.498 -1.631 -10.276 1.00 19.64 ? 395 LEU B CD1 1 ATOM 7151 C CD2 . LEU B 1 395 ? 0.850 -2.227 -8.474 1.00 21.31 ? 395 LEU B CD2 1 ATOM 7152 N N . ARG B 1 396 ? 5.132 -1.495 -4.985 1.00 22.25 ? 396 ARG B N 1 ATOM 7153 C CA . ARG B 1 396 ? 5.885 -2.103 -3.884 1.00 21.85 ? 396 ARG B CA 1 ATOM 7154 C C . ARG B 1 396 ? 4.964 -2.352 -2.680 1.00 21.77 ? 396 ARG B C 1 ATOM 7155 O O . ARG B 1 396 ? 5.204 -3.264 -1.891 1.00 21.88 ? 396 ARG B O 1 ATOM 7156 C CB . ARG B 1 396 ? 7.102 -1.248 -3.492 1.00 21.78 ? 396 ARG B CB 1 ATOM 7157 C CG . ARG B 1 396 ? 8.291 -1.334 -4.483 1.00 21.09 ? 396 ARG B CG 1 ATOM 7158 C CD . ARG B 1 396 ? 9.452 -0.439 -4.082 1.00 19.64 ? 396 ARG B CD 1 ATOM 7159 N NE . ARG B 1 396 ? 9.030 0.954 -3.979 1.00 20.98 ? 396 ARG B NE 1 ATOM 7160 C CZ . ARG B 1 396 ? 9.805 1.963 -3.599 1.00 20.27 ? 396 ARG B CZ 1 ATOM 7161 N NH1 . ARG B 1 396 ? 11.072 1.765 -3.283 1.00 22.31 ? 396 ARG B NH1 1 ATOM 7162 N NH2 . ARG B 1 396 ? 9.312 3.179 -3.530 1.00 19.89 ? 396 ARG B NH2 1 ATOM 7163 N N . ASN B 1 397 ? 3.899 -1.555 -2.563 1.00 21.30 ? 397 ASN B N 1 ATOM 7164 C CA . ASN B 1 397 ? 2.914 -1.714 -1.501 1.00 20.86 ? 397 ASN B CA 1 ATOM 7165 C C . ASN B 1 397 ? 1.729 -2.612 -1.842 1.00 20.75 ? 397 ASN B C 1 ATOM 7166 O O . ASN B 1 397 ? 0.741 -2.644 -1.097 1.00 20.64 ? 397 ASN B O 1 ATOM 7167 C CB . ASN B 1 397 ? 2.379 -0.350 -1.081 1.00 21.14 ? 397 ASN B CB 1 ATOM 7168 C CG . ASN B 1 397 ? 3.355 0.419 -0.229 1.00 21.72 ? 397 ASN B CG 1 ATOM 7169 O OD1 . ASN B 1 397 ? 3.490 1.632 -0.377 1.00 23.40 ? 397 ASN B OD1 1 ATOM 7170 N ND2 . ASN B 1 397 ? 4.054 -0.279 0.660 1.00 21.17 ? 397 ASN B ND2 1 ATOM 7171 N N . HIS B 1 398 ? 1.803 -3.324 -2.962 1.00 20.28 ? 398 HIS B N 1 ATOM 7172 C CA . HIS B 1 398 ? 0.691 -4.168 -3.371 1.00 20.29 ? 398 HIS B CA 1 ATOM 7173 C C . HIS B 1 398 ? 0.513 -5.313 -2.358 1.00 20.38 ? 398 HIS B C 1 ATOM 7174 O O . HIS B 1 398 ? 1.490 -5.973 -1.994 1.00 20.29 ? 398 HIS B O 1 ATOM 7175 C CB . HIS B 1 398 ? 0.905 -4.703 -4.788 1.00 19.99 ? 398 HIS B CB 1 ATOM 7176 C CG . HIS B 1 398 ? -0.348 -5.174 -5.453 1.00 20.19 ? 398 HIS B CG 1 ATOM 7177 N ND1 . HIS B 1 398 ? -0.975 -6.355 -5.114 1.00 19.63 ? 398 HIS B ND1 1 ATOM 7178 C CD2 . HIS B 1 398 ? -1.093 -4.623 -6.445 1.00 20.65 ? 398 HIS B CD2 1 ATOM 7179 C CE1 . HIS B 1 398 ? -2.047 -6.512 -5.871 1.00 20.10 ? 398 HIS B CE1 1 ATOM 7180 N NE2 . HIS B 1 398 ? -2.142 -5.476 -6.687 1.00 20.07 ? 398 HIS B NE2 1 ATOM 7181 N N . PRO B 1 399 ? -0.731 -5.528 -1.880 1.00 20.20 ? 399 PRO B N 1 ATOM 7182 C CA . PRO B 1 399 ? -1.011 -6.556 -0.880 1.00 20.24 ? 399 PRO B CA 1 ATOM 7183 C C . PRO B 1 399 ? -0.658 -7.989 -1.317 1.00 20.72 ? 399 PRO B C 1 ATOM 7184 O O . PRO B 1 399 ? -0.589 -8.877 -0.469 1.00 21.17 ? 399 PRO B O 1 ATOM 7185 C CB . PRO B 1 399 ? -2.524 -6.434 -0.662 1.00 20.05 ? 399 PRO B CB 1 ATOM 7186 C CG . PRO B 1 399 ? -3.036 -5.673 -1.834 1.00 19.52 ? 399 PRO B CG 1 ATOM 7187 C CD . PRO B 1 399 ? -1.939 -4.754 -2.215 1.00 20.03 ? 399 PRO B CD 1 ATOM 7188 N N . VAL B 1 400 ? -0.442 -8.217 -2.610 1.00 20.40 ? 400 VAL B N 1 ATOM 7189 C CA . VAL B 1 400 ? -0.111 -9.551 -3.092 1.00 20.57 ? 400 VAL B CA 1 ATOM 7190 C C . VAL B 1 400 ? 1.333 -9.946 -2.727 1.00 20.96 ? 400 VAL B C 1 ATOM 7191 O O . VAL B 1 400 ? 1.673 -11.135 -2.693 1.00 21.19 ? 400 VAL B O 1 ATOM 7192 C CB . VAL B 1 400 ? -0.423 -9.708 -4.610 1.00 20.43 ? 400 VAL B CB 1 ATOM 7193 C CG1 . VAL B 1 400 ? 0.234 -10.933 -5.198 1.00 20.35 ? 400 VAL B CG1 1 ATOM 7194 C CG2 . VAL B 1 400 ? -1.933 -9.791 -4.826 1.00 20.51 ? 400 VAL B CG2 1 ATOM 7195 N N . ALA B 1 401 ? 2.168 -8.954 -2.422 1.00 21.27 ? 401 ALA B N 1 ATOM 7196 C CA . ALA B 1 401 ? 3.547 -9.198 -1.972 1.00 21.41 ? 401 ALA B CA 1 ATOM 7197 C C . ALA B 1 401 ? 3.567 -10.197 -0.821 1.00 21.89 ? 401 ALA B C 1 ATOM 7198 O O . ALA B 1 401 ? 4.398 -11.090 -0.794 1.00 22.34 ? 401 ALA B O 1 ATOM 7199 C CB . ALA B 1 401 ? 4.237 -7.892 -1.567 1.00 20.68 ? 401 ALA B CB 1 ATOM 7200 N N . THR B 1 402 ? 2.632 -10.044 0.112 1.00 22.49 ? 402 THR B N 1 ATOM 7201 C CA . THR B 1 402 ? 2.495 -10.930 1.262 1.00 23.06 ? 402 THR B CA 1 ATOM 7202 C C . THR B 1 402 ? 2.105 -12.344 0.826 1.00 22.87 ? 402 THR B C 1 ATOM 7203 O O . THR B 1 402 ? 2.565 -13.332 1.391 1.00 22.58 ? 402 THR B O 1 ATOM 7204 C CB . THR B 1 402 ? 1.452 -10.359 2.253 1.00 23.07 ? 402 THR B CB 1 ATOM 7205 O OG1 . THR B 1 402 ? 2.013 -9.231 2.939 1.00 24.28 ? 402 THR B OG1 1 ATOM 7206 C CG2 . THR B 1 402 ? 1.071 -11.376 3.282 1.00 24.40 ? 402 THR B CG2 1 ATOM 7207 N N . LEU B 1 403 ? 1.259 -12.421 -0.195 1.00 23.15 ? 403 LEU B N 1 ATOM 7208 C CA . LEU B 1 403 ? 0.755 -13.693 -0.696 1.00 23.11 ? 403 LEU B CA 1 ATOM 7209 C C . LEU B 1 403 ? 1.837 -14.461 -1.437 1.00 23.34 ? 403 LEU B C 1 ATOM 7210 O O . LEU B 1 403 ? 1.929 -15.681 -1.316 1.00 23.24 ? 403 LEU B O 1 ATOM 7211 C CB . LEU B 1 403 ? -0.478 -13.456 -1.571 1.00 22.85 ? 403 LEU B CB 1 ATOM 7212 C CG . LEU B 1 403 ? -1.857 -13.428 -0.888 1.00 22.37 ? 403 LEU B CG 1 ATOM 7213 C CD1 . LEU B 1 403 ? -1.814 -13.098 0.601 1.00 21.46 ? 403 LEU B CD1 1 ATOM 7214 C CD2 . LEU B 1 403 ? -2.800 -12.486 -1.621 1.00 20.84 ? 403 LEU B CD2 1 ATOM 7215 N N . MET B 1 404 ? 2.671 -13.735 -2.178 1.00 23.73 ? 404 MET B N 1 ATOM 7216 C CA . MET B 1 404 ? 3.810 -14.331 -2.870 1.00 24.45 ? 404 MET B CA 1 ATOM 7217 C C . MET B 1 404 ? 4.811 -14.894 -1.871 1.00 24.71 ? 404 MET B C 1 ATOM 7218 O O . MET B 1 404 ? 5.371 -15.970 -2.089 1.00 24.81 ? 404 MET B O 1 ATOM 7219 C CB . MET B 1 404 ? 4.493 -13.312 -3.787 1.00 24.53 ? 404 MET B CB 1 ATOM 7220 C CG . MET B 1 404 ? 3.629 -12.857 -4.953 1.00 25.60 ? 404 MET B CG 1 ATOM 7221 S SD . MET B 1 404 ? 4.476 -11.728 -6.083 1.00 28.72 ? 404 MET B SD 1 ATOM 7222 C CE . MET B 1 404 ? 5.745 -12.791 -6.788 1.00 28.75 ? 404 MET B CE 1 ATOM 7223 N N . ALA B 1 405 ? 5.008 -14.168 -0.773 1.00 24.87 ? 405 ALA B N 1 ATOM 7224 C CA . ALA B 1 405 ? 5.932 -14.563 0.284 1.00 25.49 ? 405 ALA B CA 1 ATOM 7225 C C . ALA B 1 405 ? 5.574 -15.898 0.957 1.00 25.88 ? 405 ALA B C 1 ATOM 7226 O O . ALA B 1 405 ? 6.445 -16.542 1.535 1.00 25.98 ? 405 ALA B O 1 ATOM 7227 C CB . ALA B 1 405 ? 6.051 -13.441 1.325 1.00 25.36 ? 405 ALA B CB 1 ATOM 7228 N N . THR B 1 406 ? 4.304 -16.305 0.877 1.00 26.08 ? 406 THR B N 1 ATOM 7229 C CA . THR B 1 406 ? 3.875 -17.610 1.398 1.00 26.44 ? 406 THR B CA 1 ATOM 7230 C C . THR B 1 406 ? 3.486 -18.590 0.290 1.00 26.58 ? 406 THR B C 1 ATOM 7231 O O . THR B 1 406 ? 2.907 -19.639 0.566 1.00 27.08 ? 406 THR B O 1 ATOM 7232 C CB . THR B 1 406 ? 2.687 -17.504 2.392 1.00 26.54 ? 406 THR B CB 1 ATOM 7233 O OG1 . THR B 1 406 ? 1.502 -17.080 1.701 1.00 27.02 ? 406 THR B OG1 1 ATOM 7234 C CG2 . THR B 1 406 ? 2.998 -16.543 3.522 1.00 26.68 ? 406 THR B CG2 1 ATOM 7235 N N . GLY B 1 407 ? 3.802 -18.244 -0.957 1.00 26.55 ? 407 GLY B N 1 ATOM 7236 C CA . GLY B 1 407 ? 3.522 -19.103 -2.114 1.00 25.99 ? 407 GLY B CA 1 ATOM 7237 C C . GLY B 1 407 ? 2.053 -19.383 -2.374 1.00 25.87 ? 407 GLY B C 1 ATOM 7238 O O . GLY B 1 407 ? 1.697 -20.483 -2.763 1.00 25.85 ? 407 GLY B O 1 ATOM 7239 N N . HIS B 1 408 ? 1.200 -18.384 -2.158 1.00 25.84 ? 408 HIS B N 1 ATOM 7240 C CA . HIS B 1 408 ? -0.254 -18.508 -2.365 1.00 25.38 ? 408 HIS B CA 1 ATOM 7241 C C . HIS B 1 408 ? -0.612 -18.819 -3.829 1.00 25.12 ? 408 HIS B C 1 ATOM 7242 O O . HIS B 1 408 ? 0.058 -18.338 -4.741 1.00 25.25 ? 408 HIS B O 1 ATOM 7243 C CB . HIS B 1 408 ? -0.963 -17.229 -1.901 1.00 25.08 ? 408 HIS B CB 1 ATOM 7244 C CG . HIS B 1 408 ? -2.442 -17.388 -1.732 1.00 25.43 ? 408 HIS B CG 1 ATOM 7245 N ND1 . HIS B 1 408 ? -3.010 -17.916 -0.591 1.00 24.99 ? 408 HIS B ND1 1 ATOM 7246 C CD2 . HIS B 1 408 ? -3.472 -17.109 -2.570 1.00 24.70 ? 408 HIS B CD2 1 ATOM 7247 C CE1 . HIS B 1 408 ? -4.324 -17.954 -0.734 1.00 24.55 ? 408 HIS B CE1 1 ATOM 7248 N NE2 . HIS B 1 408 ? -4.630 -17.470 -1.924 1.00 23.58 ? 408 HIS B NE2 1 ATOM 7249 N N . PRO B 1 409 ? -1.655 -19.641 -4.063 1.00 24.92 ? 409 PRO B N 1 ATOM 7250 C CA . PRO B 1 409 ? -2.037 -19.925 -5.452 1.00 24.76 ? 409 PRO B CA 1 ATOM 7251 C C . PRO B 1 409 ? -2.543 -18.683 -6.178 1.00 24.76 ? 409 PRO B C 1 ATOM 7252 O O . PRO B 1 409 ? -3.506 -18.037 -5.736 1.00 24.87 ? 409 PRO B O 1 ATOM 7253 C CB . PRO B 1 409 ? -3.161 -20.959 -5.312 1.00 24.98 ? 409 PRO B CB 1 ATOM 7254 C CG . PRO B 1 409 ? -3.663 -20.808 -3.909 1.00 24.65 ? 409 PRO B CG 1 ATOM 7255 C CD . PRO B 1 409 ? -2.452 -20.429 -3.105 1.00 24.71 ? 409 PRO B CD 1 ATOM 7256 N N . MET B 1 410 ? -1.891 -18.352 -7.286 1.00 24.57 ? 410 MET B N 1 ATOM 7257 C CA . MET B 1 410 ? -2.209 -17.136 -8.034 1.00 24.39 ? 410 MET B CA 1 ATOM 7258 C C . MET B 1 410 ? -1.744 -17.230 -9.478 1.00 24.36 ? 410 MET B C 1 ATOM 7259 O O . MET B 1 410 ? -0.795 -17.958 -9.793 1.00 24.15 ? 410 MET B O 1 ATOM 7260 C CB . MET B 1 410 ? -1.569 -15.903 -7.373 1.00 24.23 ? 410 MET B CB 1 ATOM 7261 C CG . MET B 1 410 ? -0.043 -15.821 -7.509 1.00 24.60 ? 410 MET B CG 1 ATOM 7262 S SD . MET B 1 410 ? 0.762 -14.476 -6.596 1.00 25.99 ? 410 MET B SD 1 ATOM 7263 C CE . MET B 1 410 ? 0.439 -14.985 -4.898 1.00 23.92 ? 410 MET B CE 1 ATOM 7264 N N . VAL B 1 411 ? -2.414 -16.477 -10.345 1.00 24.18 ? 411 VAL B N 1 ATOM 7265 C CA . VAL B 1 411 ? -1.968 -16.303 -11.719 1.00 24.12 ? 411 VAL B CA 1 ATOM 7266 C C . VAL B 1 411 ? -1.890 -14.804 -12.017 1.00 24.29 ? 411 VAL B C 1 ATOM 7267 O O . VAL B 1 411 ? -2.586 -14.007 -11.374 1.00 24.31 ? 411 VAL B O 1 ATOM 7268 C CB . VAL B 1 411 ? -2.884 -17.049 -12.724 1.00 24.21 ? 411 VAL B CB 1 ATOM 7269 C CG1 . VAL B 1 411 ? -2.867 -18.553 -12.447 1.00 24.45 ? 411 VAL B CG1 1 ATOM 7270 C CG2 . VAL B 1 411 ? -4.322 -16.532 -12.672 1.00 23.67 ? 411 VAL B CG2 1 ATOM 7271 N N . ILE B 1 412 ? -1.039 -14.425 -12.973 1.00 24.17 ? 412 ILE B N 1 ATOM 7272 C CA . ILE B 1 412 ? -0.889 -13.028 -13.370 1.00 24.08 ? 412 ILE B CA 1 ATOM 7273 C C . ILE B 1 412 ? -1.620 -12.798 -14.689 1.00 24.06 ? 412 ILE B C 1 ATOM 7274 O O . ILE B 1 412 ? -1.534 -13.625 -15.604 1.00 24.49 ? 412 ILE B O 1 ATOM 7275 C CB . ILE B 1 412 ? 0.608 -12.633 -13.511 1.00 24.40 ? 412 ILE B CB 1 ATOM 7276 C CG1 . ILE B 1 412 ? 1.430 -13.076 -12.277 1.00 24.93 ? 412 ILE B CG1 1 ATOM 7277 C CG2 . ILE B 1 412 ? 0.779 -11.112 -13.824 1.00 24.38 ? 412 ILE B CG2 1 ATOM 7278 C CD1 . ILE B 1 412 ? 0.920 -12.558 -10.918 1.00 25.73 ? 412 ILE B CD1 1 ATOM 7279 N N . SER B 1 413 ? -2.351 -11.691 -14.791 1.00 23.40 ? 413 SER B N 1 ATOM 7280 C CA . SER B 1 413 ? -2.937 -11.306 -16.075 1.00 23.01 ? 413 SER B CA 1 ATOM 7281 C C . SER B 1 413 ? -2.923 -9.792 -16.250 1.00 23.03 ? 413 SER B C 1 ATOM 7282 O O . SER B 1 413 ? -2.430 -9.079 -15.385 1.00 22.94 ? 413 SER B O 1 ATOM 7283 C CB . SER B 1 413 ? -4.343 -11.896 -16.257 1.00 22.97 ? 413 SER B CB 1 ATOM 7284 O OG . SER B 1 413 ? -4.739 -11.898 -17.622 1.00 21.15 ? 413 SER B OG 1 ATOM 7285 N N . SER B 1 414 ? -3.449 -9.308 -17.373 1.00 23.26 ? 414 SER B N 1 ATOM 7286 C CA . SER B 1 414 ? -3.328 -7.886 -17.725 1.00 23.70 ? 414 SER B CA 1 ATOM 7287 C C . SER B 1 414 ? -4.647 -7.138 -17.756 1.00 23.88 ? 414 SER B C 1 ATOM 7288 O O . SER B 1 414 ? -4.652 -5.897 -17.778 1.00 24.22 ? 414 SER B O 1 ATOM 7289 C CB . SER B 1 414 ? -2.576 -7.696 -19.044 1.00 23.39 ? 414 SER B CB 1 ATOM 7290 O OG . SER B 1 414 ? -3.140 -8.482 -20.078 1.00 24.55 ? 414 SER B OG 1 ATOM 7291 N N . ASP B 1 415 ? -5.755 -7.877 -17.778 1.00 23.85 ? 415 ASP B N 1 ATOM 7292 C CA . ASP B 1 415 ? -7.068 -7.281 -17.542 1.00 24.49 ? 415 ASP B CA 1 ATOM 7293 C C . ASP B 1 415 ? -7.618 -6.485 -18.745 1.00 24.56 ? 415 ASP B C 1 ATOM 7294 O O . ASP B 1 415 ? -8.487 -6.967 -19.464 1.00 24.51 ? 415 ASP B O 1 ATOM 7295 C CB . ASP B 1 415 ? -7.012 -6.406 -16.275 1.00 24.62 ? 415 ASP B CB 1 ATOM 7296 C CG . ASP B 1 415 ? -8.355 -6.247 -15.606 1.00 25.55 ? 415 ASP B CG 1 ATOM 7297 O OD1 . ASP B 1 415 ? -9.348 -6.818 -16.101 1.00 26.95 ? 415 ASP B OD1 1 ATOM 7298 O OD2 . ASP B 1 415 ? -8.409 -5.543 -14.575 1.00 26.02 ? 415 ASP B OD2 1 ATOM 7299 N N . ASP B 1 416 ? -7.134 -5.261 -18.934 1.00 24.82 ? 416 ASP B N 1 ATOM 7300 C CA . ASP B 1 416 ? -7.496 -4.439 -20.089 1.00 25.14 ? 416 ASP B CA 1 ATOM 7301 C C . ASP B 1 416 ? -6.258 -3.685 -20.559 1.00 24.89 ? 416 ASP B C 1 ATOM 7302 O O . ASP B 1 416 ? -6.264 -2.455 -20.585 1.00 24.54 ? 416 ASP B O 1 ATOM 7303 C CB . ASP B 1 416 ? -8.565 -3.403 -19.735 1.00 25.43 ? 416 ASP B CB 1 ATOM 7304 C CG . ASP B 1 416 ? -9.800 -4.011 -19.130 1.00 27.28 ? 416 ASP B CG 1 ATOM 7305 O OD1 . ASP B 1 416 ? -10.775 -4.247 -19.880 1.00 28.71 ? 416 ASP B OD1 1 ATOM 7306 O OD2 . ASP B 1 416 ? -9.791 -4.250 -17.899 1.00 29.89 ? 416 ASP B OD2 1 ATOM 7307 N N . PRO B 1 417 ? -5.198 -4.420 -20.948 1.00 25.04 ? 417 PRO B N 1 ATOM 7308 C CA . PRO B 1 417 ? -3.902 -3.800 -21.278 1.00 25.09 ? 417 PRO B CA 1 ATOM 7309 C C . PRO B 1 417 ? -4.019 -2.586 -22.200 1.00 25.43 ? 417 PRO B C 1 ATOM 7310 O O . PRO B 1 417 ? -3.375 -1.572 -21.960 1.00 25.91 ? 417 PRO B O 1 ATOM 7311 C CB . PRO B 1 417 ? -3.130 -4.932 -21.979 1.00 25.10 ? 417 PRO B CB 1 ATOM 7312 C CG . PRO B 1 417 ? -4.156 -5.998 -22.306 1.00 24.79 ? 417 PRO B CG 1 ATOM 7313 C CD . PRO B 1 417 ? -5.217 -5.863 -21.264 1.00 24.73 ? 417 PRO B CD 1 ATOM 7314 N N . ALA B 1 418 ? -4.855 -2.684 -23.229 1.00 25.68 ? 418 ALA B N 1 ATOM 7315 C CA . ALA B 1 418 ? -5.019 -1.614 -24.208 1.00 25.98 ? 418 ALA B CA 1 ATOM 7316 C C . ALA B 1 418 ? -5.463 -0.279 -23.610 1.00 26.33 ? 418 ALA B C 1 ATOM 7317 O O . ALA B 1 418 ? -5.066 0.784 -24.107 1.00 26.32 ? 418 ALA B O 1 ATOM 7318 C CB . ALA B 1 418 ? -5.982 -2.048 -25.304 1.00 25.98 ? 418 ALA B CB 1 ATOM 7319 N N . MET B 1 419 ? -6.286 -0.328 -22.561 1.00 26.83 ? 419 MET B N 1 ATOM 7320 C CA . MET B 1 419 ? -6.784 0.896 -21.913 1.00 27.45 ? 419 MET B CA 1 ATOM 7321 C C . MET B 1 419 ? -5.716 1.599 -21.099 1.00 26.61 ? 419 MET B C 1 ATOM 7322 O O . MET B 1 419 ? -5.832 2.796 -20.831 1.00 26.24 ? 419 MET B O 1 ATOM 7323 C CB . MET B 1 419 ? -8.001 0.615 -21.022 1.00 28.26 ? 419 MET B CB 1 ATOM 7324 C CG . MET B 1 419 ? -9.306 1.218 -21.543 1.00 32.08 ? 419 MET B CG 1 ATOM 7325 S SD . MET B 1 419 ? -10.459 0.053 -22.304 1.00 40.49 ? 419 MET B SD 1 ATOM 7326 C CE . MET B 1 419 ? -9.366 -1.245 -22.858 1.00 40.15 ? 419 MET B CE 1 ATOM 7327 N N . PHE B 1 420 ? -4.687 0.842 -20.714 1.00 26.07 ? 420 PHE B N 1 ATOM 7328 C CA . PHE B 1 420 ? -3.615 1.337 -19.853 1.00 25.66 ? 420 PHE B CA 1 ATOM 7329 C C . PHE B 1 420 ? -2.349 1.638 -20.650 1.00 25.94 ? 420 PHE B C 1 ATOM 7330 O O . PHE B 1 420 ? -1.355 2.127 -20.102 1.00 26.20 ? 420 PHE B O 1 ATOM 7331 C CB . PHE B 1 420 ? -3.288 0.317 -18.755 1.00 25.39 ? 420 PHE B CB 1 ATOM 7332 C CG . PHE B 1 420 ? -4.503 -0.272 -18.070 1.00 24.38 ? 420 PHE B CG 1 ATOM 7333 C CD1 . PHE B 1 420 ? -5.598 0.524 -17.734 1.00 23.83 ? 420 PHE B CD1 1 ATOM 7334 C CD2 . PHE B 1 420 ? -4.537 -1.617 -17.745 1.00 21.73 ? 420 PHE B CD2 1 ATOM 7335 C CE1 . PHE B 1 420 ? -6.708 -0.020 -17.109 1.00 22.88 ? 420 PHE B CE1 1 ATOM 7336 C CE2 . PHE B 1 420 ? -5.631 -2.164 -17.118 1.00 21.71 ? 420 PHE B CE2 1 ATOM 7337 C CZ . PHE B 1 420 ? -6.723 -1.365 -16.795 1.00 22.72 ? 420 PHE B CZ 1 ATOM 7338 N N . GLY B 1 421 ? -2.382 1.335 -21.943 1.00 25.85 ? 421 GLY B N 1 ATOM 7339 C CA . GLY B 1 421 ? -1.234 1.544 -22.802 1.00 25.92 ? 421 GLY B CA 1 ATOM 7340 C C . GLY B 1 421 ? -0.263 0.387 -22.720 1.00 26.21 ? 421 GLY B C 1 ATOM 7341 O O . GLY B 1 421 ? 0.909 0.532 -23.056 1.00 26.23 ? 421 GLY B O 1 ATOM 7342 N N . ALA B 1 422 ? -0.748 -0.764 -22.271 1.00 26.46 ? 422 ALA B N 1 ATOM 7343 C CA . ALA B 1 422 ? 0.063 -1.972 -22.227 1.00 26.87 ? 422 ALA B CA 1 ATOM 7344 C C . ALA B 1 422 ? -0.295 -2.899 -23.387 1.00 27.34 ? 422 ALA B C 1 ATOM 7345 O O . ALA B 1 422 ? -1.215 -2.627 -24.166 1.00 27.09 ? 422 ALA B O 1 ATOM 7346 C CB . ALA B 1 422 ? -0.108 -2.688 -20.887 1.00 26.69 ? 422 ALA B CB 1 ATOM 7347 N N . LYS B 1 423 ? 0.441 -3.999 -23.490 1.00 27.87 ? 423 LYS B N 1 ATOM 7348 C CA . LYS B 1 423 ? 0.253 -4.960 -24.554 1.00 28.55 ? 423 LYS B CA 1 ATOM 7349 C C . LYS B 1 423 ? 0.526 -6.364 -24.012 1.00 28.27 ? 423 LYS B C 1 ATOM 7350 O O . LYS B 1 423 ? 1.573 -6.616 -23.401 1.00 28.29 ? 423 LYS B O 1 ATOM 7351 C CB . LYS B 1 423 ? 1.201 -4.641 -25.717 1.00 28.88 ? 423 LYS B CB 1 ATOM 7352 C CG . LYS B 1 423 ? 0.585 -4.842 -27.100 1.00 32.06 ? 423 LYS B CG 1 ATOM 7353 C CD . LYS B 1 423 ? 1.589 -5.021 -28.266 1.00 36.95 ? 423 LYS B CD 1 ATOM 7354 C CE . LYS B 1 423 ? 3.062 -4.975 -27.871 1.00 39.76 ? 423 LYS B CE 1 ATOM 7355 N NZ . LYS B 1 423 ? 3.942 -4.856 -29.084 1.00 42.55 ? 423 LYS B NZ 1 ATOM 7356 N N . GLY B 1 424 ? -0.413 -7.277 -24.231 1.00 28.05 ? 424 GLY B N 1 ATOM 7357 C CA . GLY B 1 424 ? -0.207 -8.670 -23.865 1.00 27.59 ? 424 GLY B CA 1 ATOM 7358 C C . GLY B 1 424 ? -0.095 -8.852 -22.368 1.00 27.59 ? 424 GLY B C 1 ATOM 7359 O O . GLY B 1 424 ? -0.959 -8.401 -21.621 1.00 27.75 ? 424 GLY B O 1 ATOM 7360 N N . LEU B 1 425 ? 0.993 -9.480 -21.931 1.00 27.41 ? 425 LEU B N 1 ATOM 7361 C CA . LEU B 1 425 ? 1.139 -9.910 -20.547 1.00 26.93 ? 425 LEU B CA 1 ATOM 7362 C C . LEU B 1 425 ? 2.471 -9.503 -19.894 1.00 26.86 ? 425 LEU B C 1 ATOM 7363 O O . LEU B 1 425 ? 2.627 -9.639 -18.677 1.00 27.34 ? 425 LEU B O 1 ATOM 7364 C CB . LEU B 1 425 ? 0.983 -11.428 -20.505 1.00 26.72 ? 425 LEU B CB 1 ATOM 7365 C CG . LEU B 1 425 ? 0.003 -12.080 -19.530 1.00 27.02 ? 425 LEU B CG 1 ATOM 7366 C CD1 . LEU B 1 425 ? -1.396 -11.439 -19.555 1.00 25.56 ? 425 LEU B CD1 1 ATOM 7367 C CD2 . LEU B 1 425 ? -0.088 -13.556 -19.836 1.00 25.48 ? 425 LEU B CD2 1 ATOM 7368 N N . SER B 1 426 ? 3.421 -9.002 -20.688 1.00 26.24 ? 426 SER B N 1 ATOM 7369 C CA . SER B 1 426 ? 4.807 -8.826 -20.223 1.00 25.86 ? 426 SER B CA 1 ATOM 7370 C C . SER B 1 426 ? 4.984 -7.670 -19.254 1.00 25.47 ? 426 SER B C 1 ATOM 7371 O O . SER B 1 426 ? 5.812 -7.736 -18.341 1.00 25.18 ? 426 SER B O 1 ATOM 7372 C CB . SER B 1 426 ? 5.781 -8.662 -21.401 1.00 25.88 ? 426 SER B CB 1 ATOM 7373 O OG . SER B 1 426 ? 5.891 -9.855 -22.159 1.00 26.12 ? 426 SER B OG 1 ATOM 7374 N N . TYR B 1 427 ? 4.223 -6.607 -19.471 1.00 25.35 ? 427 TYR B N 1 ATOM 7375 C CA . TYR B 1 427 ? 4.256 -5.449 -18.590 1.00 25.47 ? 427 TYR B CA 1 ATOM 7376 C C . TYR B 1 427 ? 3.806 -5.817 -17.183 1.00 25.11 ? 427 TYR B C 1 ATOM 7377 O O . TYR B 1 427 ? 4.427 -5.401 -16.215 1.00 24.83 ? 427 TYR B O 1 ATOM 7378 C CB . TYR B 1 427 ? 3.394 -4.316 -19.151 1.00 25.72 ? 427 TYR B CB 1 ATOM 7379 C CG . TYR B 1 427 ? 3.916 -3.729 -20.444 1.00 26.58 ? 427 TYR B CG 1 ATOM 7380 C CD1 . TYR B 1 427 ? 3.469 -4.209 -21.680 1.00 27.52 ? 427 TYR B CD1 1 ATOM 7381 C CD2 . TYR B 1 427 ? 4.852 -2.691 -20.433 1.00 26.85 ? 427 TYR B CD2 1 ATOM 7382 C CE1 . TYR B 1 427 ? 3.944 -3.675 -22.881 1.00 27.43 ? 427 TYR B CE1 1 ATOM 7383 C CE2 . TYR B 1 427 ? 5.328 -2.142 -21.626 1.00 28.40 ? 427 TYR B CE2 1 ATOM 7384 C CZ . TYR B 1 427 ? 4.870 -2.646 -22.847 1.00 28.41 ? 427 TYR B CZ 1 ATOM 7385 O OH . TYR B 1 427 ? 5.338 -2.114 -24.024 1.00 28.59 ? 427 TYR B OH 1 ATOM 7386 N N . ASP B 1 428 ? 2.744 -6.616 -17.079 1.00 25.27 ? 428 ASP B N 1 ATOM 7387 C CA . ASP B 1 428 ? 2.253 -7.075 -15.780 1.00 25.51 ? 428 ASP B CA 1 ATOM 7388 C C . ASP B 1 428 ? 3.210 -8.059 -15.104 1.00 24.93 ? 428 ASP B C 1 ATOM 7389 O O . ASP B 1 428 ? 3.379 -8.017 -13.887 1.00 24.96 ? 428 ASP B O 1 ATOM 7390 C CB . ASP B 1 428 ? 0.820 -7.604 -15.879 1.00 25.99 ? 428 ASP B CB 1 ATOM 7391 C CG . ASP B 1 428 ? -0.208 -6.469 -16.114 1.00 28.58 ? 428 ASP B CG 1 ATOM 7392 O OD1 . ASP B 1 428 ? -0.850 -6.026 -15.130 1.00 31.31 ? 428 ASP B OD1 1 ATOM 7393 O OD2 . ASP B 1 428 ? -0.349 -5.991 -17.268 1.00 29.37 ? 428 ASP B OD2 1 ATOM 7394 N N . PHE B 1 429 ? 3.862 -8.910 -15.894 1.00 24.42 ? 429 PHE B N 1 ATOM 7395 C CA . PHE B 1 429 ? 4.932 -9.783 -15.380 1.00 24.05 ? 429 PHE B CA 1 ATOM 7396 C C . PHE B 1 429 ? 6.133 -8.982 -14.868 1.00 24.08 ? 429 PHE B C 1 ATOM 7397 O O . PHE B 1 429 ? 6.789 -9.387 -13.909 1.00 24.22 ? 429 PHE B O 1 ATOM 7398 C CB . PHE B 1 429 ? 5.386 -10.799 -16.442 1.00 23.69 ? 429 PHE B CB 1 ATOM 7399 C CG . PHE B 1 429 ? 4.732 -12.151 -16.309 1.00 23.30 ? 429 PHE B CG 1 ATOM 7400 C CD1 . PHE B 1 429 ? 3.467 -12.387 -16.848 1.00 23.09 ? 429 PHE B CD1 1 ATOM 7401 C CD2 . PHE B 1 429 ? 5.383 -13.192 -15.650 1.00 22.57 ? 429 PHE B CD2 1 ATOM 7402 C CE1 . PHE B 1 429 ? 2.858 -13.638 -16.733 1.00 22.28 ? 429 PHE B CE1 1 ATOM 7403 C CE2 . PHE B 1 429 ? 4.781 -14.441 -15.525 1.00 22.50 ? 429 PHE B CE2 1 ATOM 7404 C CZ . PHE B 1 429 ? 3.514 -14.665 -16.072 1.00 22.14 ? 429 PHE B CZ 1 ATOM 7405 N N . TYR B 1 430 ? 6.410 -7.844 -15.501 1.00 23.87 ? 430 TYR B N 1 ATOM 7406 C CA . TYR B 1 430 ? 7.468 -6.960 -15.031 1.00 23.84 ? 430 TYR B CA 1 ATOM 7407 C C . TYR B 1 430 ? 7.162 -6.409 -13.634 1.00 23.67 ? 430 TYR B C 1 ATOM 7408 O O . TYR B 1 430 ? 8.007 -6.468 -12.729 1.00 23.90 ? 430 TYR B O 1 ATOM 7409 C CB . TYR B 1 430 ? 7.717 -5.816 -16.024 1.00 23.80 ? 430 TYR B CB 1 ATOM 7410 C CG . TYR B 1 430 ? 8.746 -4.828 -15.524 1.00 24.43 ? 430 TYR B CG 1 ATOM 7411 C CD1 . TYR B 1 430 ? 8.367 -3.736 -14.739 1.00 24.11 ? 430 TYR B CD1 1 ATOM 7412 C CD2 . TYR B 1 430 ? 10.104 -4.995 -15.811 1.00 25.08 ? 430 TYR B CD2 1 ATOM 7413 C CE1 . TYR B 1 430 ? 9.306 -2.837 -14.257 1.00 23.94 ? 430 TYR B CE1 1 ATOM 7414 C CE2 . TYR B 1 430 ? 11.052 -4.091 -15.336 1.00 24.87 ? 430 TYR B CE2 1 ATOM 7415 C CZ . TYR B 1 430 ? 10.640 -3.017 -14.557 1.00 24.52 ? 430 TYR B CZ 1 ATOM 7416 O OH . TYR B 1 430 ? 11.565 -2.122 -14.084 1.00 26.53 ? 430 TYR B OH 1 ATOM 7417 N N . GLU B 1 431 ? 5.949 -5.884 -13.469 1.00 23.22 ? 431 GLU B N 1 ATOM 7418 C CA . GLU B 1 431 ? 5.502 -5.293 -12.210 1.00 22.35 ? 431 GLU B CA 1 ATOM 7419 C C . GLU B 1 431 ? 5.533 -6.315 -11.077 1.00 22.23 ? 431 GLU B C 1 ATOM 7420 O O . GLU B 1 431 ? 6.003 -6.024 -9.962 1.00 21.79 ? 431 GLU B O 1 ATOM 7421 C CB . GLU B 1 431 ? 4.097 -4.710 -12.366 1.00 22.12 ? 431 GLU B CB 1 ATOM 7422 C CG . GLU B 1 431 ? 3.958 -3.661 -13.476 1.00 21.81 ? 431 GLU B CG 1 ATOM 7423 C CD . GLU B 1 431 ? 4.590 -2.312 -13.125 1.00 22.09 ? 431 GLU B CD 1 ATOM 7424 O OE1 . GLU B 1 431 ? 5.664 -2.290 -12.485 1.00 21.23 ? 431 GLU B OE1 1 ATOM 7425 O OE2 . GLU B 1 431 ? 4.012 -1.268 -13.500 1.00 22.10 ? 431 GLU B OE2 1 ATOM 7426 N N . VAL B 1 432 ? 5.046 -7.518 -11.366 1.00 21.81 ? 432 VAL B N 1 ATOM 7427 C CA . VAL B 1 432 ? 5.055 -8.576 -10.371 1.00 21.75 ? 432 VAL B CA 1 ATOM 7428 C C . VAL B 1 432 ? 6.487 -8.917 -9.978 1.00 22.05 ? 432 VAL B C 1 ATOM 7429 O O . VAL B 1 432 ? 6.832 -8.876 -8.800 1.00 21.82 ? 432 VAL B O 1 ATOM 7430 C CB . VAL B 1 432 ? 4.311 -9.822 -10.863 1.00 21.51 ? 432 VAL B CB 1 ATOM 7431 C CG1 . VAL B 1 432 ? 4.608 -11.024 -9.969 1.00 21.20 ? 432 VAL B CG1 1 ATOM 7432 C CG2 . VAL B 1 432 ? 2.825 -9.545 -10.903 1.00 21.03 ? 432 VAL B CG2 1 ATOM 7433 N N . PHE B 1 433 ? 7.312 -9.204 -10.984 1.00 22.59 ? 433 PHE B N 1 ATOM 7434 C CA . PHE B 1 433 ? 8.679 -9.688 -10.796 1.00 23.10 ? 433 PHE B CA 1 ATOM 7435 C C . PHE B 1 433 ? 9.620 -8.643 -10.193 1.00 23.57 ? 433 PHE B C 1 ATOM 7436 O O . PHE B 1 433 ? 10.495 -8.980 -9.389 1.00 23.74 ? 433 PHE B O 1 ATOM 7437 C CB . PHE B 1 433 ? 9.227 -10.194 -12.135 1.00 22.91 ? 433 PHE B CB 1 ATOM 7438 C CG . PHE B 1 433 ? 10.582 -10.835 -12.046 1.00 23.23 ? 433 PHE B CG 1 ATOM 7439 C CD1 . PHE B 1 433 ? 10.755 -12.052 -11.375 1.00 23.54 ? 433 PHE B CD1 1 ATOM 7440 C CD2 . PHE B 1 433 ? 11.681 -10.246 -12.666 1.00 23.13 ? 433 PHE B CD2 1 ATOM 7441 C CE1 . PHE B 1 433 ? 11.999 -12.650 -11.301 1.00 24.16 ? 433 PHE B CE1 1 ATOM 7442 C CE2 . PHE B 1 433 ? 12.936 -10.844 -12.600 1.00 23.77 ? 433 PHE B CE2 1 ATOM 7443 C CZ . PHE B 1 433 ? 13.094 -12.046 -11.914 1.00 24.11 ? 433 PHE B CZ 1 ATOM 7444 N N . MET B 1 434 ? 9.452 -7.381 -10.581 1.00 24.03 ? 434 MET B N 1 ATOM 7445 C CA . MET B 1 434 ? 10.336 -6.326 -10.080 1.00 24.91 ? 434 MET B CA 1 ATOM 7446 C C . MET B 1 434 ? 9.767 -5.565 -8.877 1.00 24.75 ? 434 MET B C 1 ATOM 7447 O O . MET B 1 434 ? 10.507 -5.202 -7.966 1.00 24.99 ? 434 MET B O 1 ATOM 7448 C CB . MET B 1 434 ? 10.709 -5.356 -11.198 1.00 25.08 ? 434 MET B CB 1 ATOM 7449 C CG . MET B 1 434 ? 11.522 -5.992 -12.315 1.00 27.05 ? 434 MET B CG 1 ATOM 7450 S SD . MET B 1 434 ? 13.204 -6.427 -11.817 1.00 30.54 ? 434 MET B SD 1 ATOM 7451 C CE . MET B 1 434 ? 13.941 -4.791 -11.680 1.00 29.06 ? 434 MET B CE 1 ATOM 7452 N N . GLY B 1 435 ? 8.456 -5.348 -8.874 1.00 24.58 ? 435 GLY B N 1 ATOM 7453 C CA . GLY B 1 435 ? 7.812 -4.550 -7.838 1.00 24.68 ? 435 GLY B CA 1 ATOM 7454 C C . GLY B 1 435 ? 7.218 -5.329 -6.678 1.00 24.48 ? 435 GLY B C 1 ATOM 7455 O O . GLY B 1 435 ? 7.573 -5.100 -5.524 1.00 25.11 ? 435 GLY B O 1 ATOM 7456 N N . ILE B 1 436 ? 6.315 -6.248 -6.984 1.00 23.99 ? 436 ILE B N 1 ATOM 7457 C CA . ILE B 1 436 ? 5.545 -6.931 -5.959 1.00 23.37 ? 436 ILE B CA 1 ATOM 7458 C C . ILE B 1 436 ? 6.339 -8.070 -5.309 1.00 23.41 ? 436 ILE B C 1 ATOM 7459 O O . ILE B 1 436 ? 6.243 -8.302 -4.110 1.00 23.27 ? 436 ILE B O 1 ATOM 7460 C CB . ILE B 1 436 ? 4.200 -7.435 -6.535 1.00 23.33 ? 436 ILE B CB 1 ATOM 7461 C CG1 . ILE B 1 436 ? 3.408 -6.265 -7.151 1.00 22.37 ? 436 ILE B CG1 1 ATOM 7462 C CG2 . ILE B 1 436 ? 3.387 -8.152 -5.467 1.00 22.85 ? 436 ILE B CG2 1 ATOM 7463 C CD1 . ILE B 1 436 ? 2.183 -6.690 -7.959 1.00 20.57 ? 436 ILE B CD1 1 ATOM 7464 N N . GLY B 1 437 ? 7.134 -8.770 -6.105 1.00 23.64 ? 437 GLY B N 1 ATOM 7465 C CA . GLY B 1 437 ? 7.857 -9.942 -5.628 1.00 23.78 ? 437 GLY B CA 1 ATOM 7466 C C . GLY B 1 437 ? 9.118 -9.612 -4.855 1.00 24.07 ? 437 GLY B C 1 ATOM 7467 O O . GLY B 1 437 ? 9.661 -10.465 -4.164 1.00 24.08 ? 437 GLY B O 1 ATOM 7468 N N . GLY B 1 438 ? 9.585 -8.372 -4.972 1.00 24.80 ? 438 GLY B N 1 ATOM 7469 C CA . GLY B 1 438 ? 10.807 -7.939 -4.299 1.00 25.53 ? 438 GLY B CA 1 ATOM 7470 C C . GLY B 1 438 ? 12.048 -8.464 -4.985 1.00 26.07 ? 438 GLY B C 1 ATOM 7471 O O . GLY B 1 438 ? 11.962 -9.119 -6.026 1.00 26.05 ? 438 GLY B O 1 ATOM 7472 N N . MET B 1 439 ? 13.202 -8.187 -4.383 1.00 26.80 ? 439 MET B N 1 ATOM 7473 C CA . MET B 1 439 ? 14.498 -8.454 -5.012 1.00 27.60 ? 439 MET B CA 1 ATOM 7474 C C . MET B 1 439 ? 14.834 -9.942 -5.119 1.00 27.74 ? 439 MET B C 1 ATOM 7475 O O . MET B 1 439 ? 15.615 -10.338 -5.975 1.00 27.72 ? 439 MET B O 1 ATOM 7476 C CB . MET B 1 439 ? 15.622 -7.698 -4.292 1.00 27.89 ? 439 MET B CB 1 ATOM 7477 C CG . MET B 1 439 ? 16.989 -7.847 -4.965 1.00 29.96 ? 439 MET B CG 1 ATOM 7478 S SD . MET B 1 439 ? 18.334 -7.031 -4.101 1.00 35.52 ? 439 MET B SD 1 ATOM 7479 C CE . MET B 1 439 ? 18.334 -5.435 -4.926 1.00 31.11 ? 439 MET B CE 1 ATOM 7480 N N . LYS B 1 440 ? 14.226 -10.760 -4.270 1.00 28.17 ? 440 LYS B N 1 ATOM 7481 C CA . LYS B 1 440 ? 14.540 -12.184 -4.218 1.00 28.62 ? 440 LYS B CA 1 ATOM 7482 C C . LYS B 1 440 ? 13.638 -13.042 -5.122 1.00 28.74 ? 440 LYS B C 1 ATOM 7483 O O . LYS B 1 440 ? 13.824 -14.254 -5.205 1.00 29.25 ? 440 LYS B O 1 ATOM 7484 C CB . LYS B 1 440 ? 14.469 -12.686 -2.773 1.00 28.86 ? 440 LYS B CB 1 ATOM 7485 C CG . LYS B 1 440 ? 15.502 -12.081 -1.843 1.00 29.94 ? 440 LYS B CG 1 ATOM 7486 C CD . LYS B 1 440 ? 16.617 -13.058 -1.598 1.00 32.07 ? 440 LYS B CD 1 ATOM 7487 C CE . LYS B 1 440 ? 17.114 -12.951 -0.170 1.00 33.87 ? 440 LYS B CE 1 ATOM 7488 N NZ . LYS B 1 440 ? 18.218 -11.980 -0.120 1.00 35.11 ? 440 LYS B NZ 1 ATOM 7489 N N . ALA B 1 441 ? 12.653 -12.427 -5.775 1.00 28.44 ? 441 ALA B N 1 ATOM 7490 C CA . ALA B 1 441 ? 11.871 -13.131 -6.792 1.00 28.30 ? 441 ALA B CA 1 ATOM 7491 C C . ALA B 1 441 ? 12.802 -13.490 -7.946 1.00 28.25 ? 441 ALA B C 1 ATOM 7492 O O . ALA B 1 441 ? 13.484 -12.620 -8.493 1.00 28.02 ? 441 ALA B O 1 ATOM 7493 C CB . ALA B 1 441 ? 10.704 -12.274 -7.281 1.00 27.89 ? 441 ALA B CB 1 ATOM 7494 N N . ASP B 1 442 ? 12.830 -14.770 -8.303 1.00 28.32 ? 442 ASP B N 1 ATOM 7495 C CA . ASP B 1 442 ? 13.787 -15.275 -9.288 1.00 28.52 ? 442 ASP B CA 1 ATOM 7496 C C . ASP B 1 442 ? 13.130 -16.045 -10.448 1.00 28.60 ? 442 ASP B C 1 ATOM 7497 O O . ASP B 1 442 ? 11.921 -15.920 -10.681 1.00 28.74 ? 442 ASP B O 1 ATOM 7498 C CB . ASP B 1 442 ? 14.851 -16.127 -8.580 1.00 28.70 ? 442 ASP B CB 1 ATOM 7499 C CG . ASP B 1 442 ? 14.276 -17.371 -7.911 1.00 29.27 ? 442 ASP B CG 1 ATOM 7500 O OD1 . ASP B 1 442 ? 13.084 -17.698 -8.118 1.00 30.58 ? 442 ASP B OD1 1 ATOM 7501 O OD2 . ASP B 1 442 ? 15.035 -18.035 -7.171 1.00 30.20 ? 442 ASP B OD2 1 ATOM 7502 N N . LEU B 1 443 ? 13.926 -16.843 -11.163 1.00 28.43 ? 443 LEU B N 1 ATOM 7503 C CA . LEU B 1 443 ? 13.442 -17.626 -12.299 1.00 28.16 ? 443 LEU B CA 1 ATOM 7504 C C . LEU B 1 443 ? 12.390 -18.646 -11.867 1.00 27.87 ? 443 LEU B C 1 ATOM 7505 O O . LEU B 1 443 ? 11.497 -18.986 -12.645 1.00 27.74 ? 443 LEU B O 1 ATOM 7506 C CB . LEU B 1 443 ? 14.605 -18.314 -13.037 1.00 28.05 ? 443 LEU B CB 1 ATOM 7507 C CG . LEU B 1 443 ? 14.301 -18.943 -14.411 1.00 28.63 ? 443 LEU B CG 1 ATOM 7508 C CD1 . LEU B 1 443 ? 14.047 -17.899 -15.503 1.00 28.35 ? 443 LEU B CD1 1 ATOM 7509 C CD2 . LEU B 1 443 ? 15.408 -19.890 -14.846 1.00 28.06 ? 443 LEU B CD2 1 ATOM 7510 N N . ARG B 1 444 ? 12.499 -19.120 -10.627 1.00 27.60 ? 444 ARG B N 1 ATOM 7511 C CA . ARG B 1 444 ? 11.520 -20.056 -10.061 1.00 27.67 ? 444 ARG B CA 1 ATOM 7512 C C . ARG B 1 444 ? 10.131 -19.420 -9.912 1.00 27.41 ? 444 ARG B C 1 ATOM 7513 O O . ARG B 1 444 ? 9.123 -20.036 -10.244 1.00 27.39 ? 444 ARG B O 1 ATOM 7514 C CB . ARG B 1 444 ? 11.991 -20.578 -8.703 1.00 27.93 ? 444 ARG B CB 1 ATOM 7515 C CG . ARG B 1 444 ? 13.191 -21.485 -8.752 1.00 27.97 ? 444 ARG B CG 1 ATOM 7516 C CD . ARG B 1 444 ? 13.590 -21.898 -7.349 1.00 29.00 ? 444 ARG B CD 1 ATOM 7517 N NE . ARG B 1 444 ? 14.832 -22.670 -7.345 1.00 30.77 ? 444 ARG B NE 1 ATOM 7518 C CZ . ARG B 1 444 ? 16.048 -22.133 -7.449 1.00 31.04 ? 444 ARG B CZ 1 ATOM 7519 N NH1 . ARG B 1 444 ? 16.194 -20.813 -7.565 1.00 31.26 ? 444 ARG B NH1 1 ATOM 7520 N NH2 . ARG B 1 444 ? 17.121 -22.916 -7.440 1.00 30.54 ? 444 ARG B NH2 1 ATOM 7521 N N . THR B 1 445 ? 10.099 -18.192 -9.395 1.00 27.15 ? 445 THR B N 1 ATOM 7522 C CA . THR B 1 445 ? 8.870 -17.410 -9.292 1.00 26.93 ? 445 THR B CA 1 ATOM 7523 C C . THR B 1 445 ? 8.163 -17.342 -10.645 1.00 26.80 ? 445 THR B C 1 ATOM 7524 O O . THR B 1 445 ? 6.962 -17.636 -10.747 1.00 26.67 ? 445 THR B O 1 ATOM 7525 C CB . THR B 1 445 ? 9.149 -15.971 -8.809 1.00 27.01 ? 445 THR B CB 1 ATOM 7526 O OG1 . THR B 1 445 ? 9.906 -15.997 -7.589 1.00 27.27 ? 445 THR B OG1 1 ATOM 7527 C CG2 . THR B 1 445 ? 7.851 -15.230 -8.578 1.00 26.21 ? 445 THR B CG2 1 ATOM 7528 N N . LEU B 1 446 ? 8.926 -16.963 -11.670 1.00 26.44 ? 446 LEU B N 1 ATOM 7529 C CA . LEU B 1 446 ? 8.425 -16.821 -13.024 1.00 26.33 ? 446 LEU B CA 1 ATOM 7530 C C . LEU B 1 446 ? 7.879 -18.141 -13.532 1.00 26.67 ? 446 LEU B C 1 ATOM 7531 O O . LEU B 1 446 ? 6.748 -18.213 -14.032 1.00 26.80 ? 446 LEU B O 1 ATOM 7532 C CB . LEU B 1 446 ? 9.532 -16.299 -13.950 1.00 25.89 ? 446 LEU B CB 1 ATOM 7533 C CG . LEU B 1 446 ? 10.023 -14.860 -13.729 1.00 25.50 ? 446 LEU B CG 1 ATOM 7534 C CD1 . LEU B 1 446 ? 11.241 -14.536 -14.599 1.00 23.03 ? 446 LEU B CD1 1 ATOM 7535 C CD2 . LEU B 1 446 ? 8.911 -13.837 -13.967 1.00 25.05 ? 446 LEU B CD2 1 ATOM 7536 N N . LYS B 1 447 ? 8.679 -19.189 -13.377 1.00 27.18 ? 447 LYS B N 1 ATOM 7537 C CA . LYS B 1 447 ? 8.318 -20.510 -13.865 1.00 27.53 ? 447 LYS B CA 1 ATOM 7538 C C . LYS B 1 447 ? 7.025 -20.958 -13.211 1.00 27.32 ? 447 LYS B C 1 ATOM 7539 O O . LYS B 1 447 ? 6.090 -21.360 -13.894 1.00 27.58 ? 447 LYS B O 1 ATOM 7540 C CB . LYS B 1 447 ? 9.446 -21.510 -13.600 1.00 27.80 ? 447 LYS B CB 1 ATOM 7541 C CG . LYS B 1 447 ? 9.395 -22.730 -14.491 1.00 28.91 ? 447 LYS B CG 1 ATOM 7542 C CD . LYS B 1 447 ? 10.510 -23.703 -14.173 1.00 30.89 ? 447 LYS B CD 1 ATOM 7543 C CE . LYS B 1 447 ? 10.465 -24.868 -15.142 1.00 32.11 ? 447 LYS B CE 1 ATOM 7544 N NZ . LYS B 1 447 ? 11.576 -25.817 -14.924 1.00 33.04 ? 447 LYS B NZ 1 ATOM 7545 N N . GLN B 1 448 ? 6.967 -20.855 -11.889 1.00 27.43 ? 448 GLN B N 1 ATOM 7546 C CA . GLN B 1 448 ? 5.764 -21.206 -11.133 1.00 27.53 ? 448 GLN B CA 1 ATOM 7547 C C . GLN B 1 448 ? 4.514 -20.468 -11.622 1.00 27.27 ? 448 GLN B C 1 ATOM 7548 O O . GLN B 1 448 ? 3.444 -21.072 -11.743 1.00 27.30 ? 448 GLN B O 1 ATOM 7549 C CB . GLN B 1 448 ? 5.970 -20.939 -9.644 1.00 27.58 ? 448 GLN B CB 1 ATOM 7550 C CG . GLN B 1 448 ? 4.885 -21.505 -8.754 1.00 28.96 ? 448 GLN B CG 1 ATOM 7551 C CD . GLN B 1 448 ? 4.845 -23.014 -8.785 1.00 31.13 ? 448 GLN B CD 1 ATOM 7552 O OE1 . GLN B 1 448 ? 5.694 -23.676 -8.195 1.00 33.55 ? 448 GLN B OE1 1 ATOM 7553 N NE2 . GLN B 1 448 ? 3.856 -23.567 -9.472 1.00 30.59 ? 448 GLN B NE2 1 ATOM 7554 N N . LEU B 1 449 ? 4.654 -19.171 -11.895 1.00 26.82 ? 449 LEU B N 1 ATOM 7555 C CA . LEU B 1 449 ? 3.536 -18.355 -12.364 1.00 26.59 ? 449 LEU B CA 1 ATOM 7556 C C . LEU B 1 449 ? 3.084 -18.749 -13.764 1.00 26.68 ? 449 LEU B C 1 ATOM 7557 O O . LEU B 1 449 ? 1.878 -18.728 -14.056 1.00 26.58 ? 449 LEU B O 1 ATOM 7558 C CB . LEU B 1 449 ? 3.880 -16.867 -12.315 1.00 26.68 ? 449 LEU B CB 1 ATOM 7559 C CG . LEU B 1 449 ? 3.882 -16.207 -10.932 1.00 26.27 ? 449 LEU B CG 1 ATOM 7560 C CD1 . LEU B 1 449 ? 4.568 -14.848 -10.985 1.00 25.94 ? 449 LEU B CD1 1 ATOM 7561 C CD2 . LEU B 1 449 ? 2.478 -16.089 -10.349 1.00 26.05 ? 449 LEU B CD2 1 ATOM 7562 N N . ALA B 1 450 ? 4.044 -19.120 -14.615 1.00 26.49 ? 450 ALA B N 1 ATOM 7563 C CA . ALA B 1 450 ? 3.737 -19.661 -15.945 1.00 26.50 ? 450 ALA B CA 1 ATOM 7564 C C . ALA B 1 450 ? 2.959 -20.978 -15.862 1.00 26.54 ? 450 ALA B C 1 ATOM 7565 O O . ALA B 1 450 ? 1.936 -21.140 -16.529 1.00 26.52 ? 450 ALA B O 1 ATOM 7566 C CB . ALA B 1 450 ? 5.008 -19.840 -16.760 1.00 26.36 ? 450 ALA B CB 1 ATOM 7567 N N . MET B 1 451 ? 3.435 -21.903 -15.032 1.00 26.63 ? 451 MET B N 1 ATOM 7568 C CA . MET B 1 451 ? 2.796 -23.214 -14.885 1.00 26.93 ? 451 MET B CA 1 ATOM 7569 C C . MET B 1 451 ? 1.422 -23.119 -14.216 1.00 26.80 ? 451 MET B C 1 ATOM 7570 O O . MET B 1 451 ? 0.470 -23.771 -14.638 1.00 26.82 ? 451 MET B O 1 ATOM 7571 C CB . MET B 1 451 ? 3.718 -24.189 -14.142 1.00 26.96 ? 451 MET B CB 1 ATOM 7572 C CG . MET B 1 451 ? 5.008 -24.498 -14.918 1.00 28.63 ? 451 MET B CG 1 ATOM 7573 S SD . MET B 1 451 ? 6.070 -25.793 -14.221 1.00 30.66 ? 451 MET B SD 1 ATOM 7574 C CE . MET B 1 451 ? 6.338 -25.174 -12.554 1.00 29.15 ? 451 MET B CE 1 ATOM 7575 N N . ASN B 1 452 ? 1.320 -22.291 -13.181 1.00 27.02 ? 452 ASN B N 1 ATOM 7576 C CA . ASN B 1 452 ? 0.031 -21.997 -12.543 1.00 27.12 ? 452 ASN B CA 1 ATOM 7577 C C . ASN B 1 452 ? -1.056 -21.621 -13.538 1.00 27.02 ? 452 ASN B C 1 ATOM 7578 O O . ASN B 1 452 ? -2.193 -22.050 -13.396 1.00 27.09 ? 452 ASN B O 1 ATOM 7579 C CB . ASN B 1 452 ? 0.173 -20.881 -11.499 1.00 26.90 ? 452 ASN B CB 1 ATOM 7580 C CG . ASN B 1 452 ? 0.806 -21.363 -10.210 1.00 27.00 ? 452 ASN B CG 1 ATOM 7581 O OD1 . ASN B 1 452 ? 1.072 -22.557 -10.042 1.00 26.64 ? 452 ASN B OD1 1 ATOM 7582 N ND2 . ASN B 1 452 ? 1.050 -20.437 -9.287 1.00 26.78 ? 452 ASN B ND2 1 ATOM 7583 N N . SER B 1 453 ? -0.699 -20.827 -14.544 1.00 27.12 ? 453 SER B N 1 ATOM 7584 C CA . SER B 1 453 ? -1.669 -20.353 -15.524 1.00 27.61 ? 453 SER B CA 1 ATOM 7585 C C . SER B 1 453 ? -2.198 -21.467 -16.434 1.00 27.58 ? 453 SER B C 1 ATOM 7586 O O . SER B 1 453 ? -3.248 -21.304 -17.066 1.00 27.54 ? 453 SER B O 1 ATOM 7587 C CB . SER B 1 453 ? -1.087 -19.198 -16.350 1.00 27.78 ? 453 SER B CB 1 ATOM 7588 O OG . SER B 1 453 ? -0.136 -19.652 -17.300 1.00 28.93 ? 453 SER B OG 1 ATOM 7589 N N . ILE B 1 454 ? -1.468 -22.583 -16.498 1.00 27.46 ? 454 ILE B N 1 ATOM 7590 C CA . ILE B 1 454 ? -1.933 -23.782 -17.200 1.00 27.45 ? 454 ILE B CA 1 ATOM 7591 C C . ILE B 1 454 ? -2.733 -24.652 -16.224 1.00 27.55 ? 454 ILE B C 1 ATOM 7592 O O . ILE B 1 454 ? -3.805 -25.169 -16.558 1.00 27.68 ? 454 ILE B O 1 ATOM 7593 C CB . ILE B 1 454 ? -0.752 -24.592 -17.831 1.00 27.53 ? 454 ILE B CB 1 ATOM 7594 C CG1 . ILE B 1 454 ? -0.022 -23.746 -18.888 1.00 27.63 ? 454 ILE B CG1 1 ATOM 7595 C CG2 . ILE B 1 454 ? -1.246 -25.913 -18.441 1.00 26.76 ? 454 ILE B CG2 1 ATOM 7596 C CD1 . ILE B 1 454 ? 1.346 -24.302 -19.336 1.00 27.38 ? 454 ILE B CD1 1 ATOM 7597 N N . LYS B 1 455 ? -2.212 -24.792 -15.009 1.00 27.37 ? 455 LYS B N 1 ATOM 7598 C CA . LYS B 1 455 ? -2.872 -25.577 -13.976 1.00 27.24 ? 455 LYS B CA 1 ATOM 7599 C C . LYS B 1 455 ? -4.270 -25.041 -13.636 1.00 27.09 ? 455 LYS B C 1 ATOM 7600 O O . LYS B 1 455 ? -5.219 -25.815 -13.516 1.00 27.30 ? 455 LYS B O 1 ATOM 7601 C CB . LYS B 1 455 ? -2.004 -25.651 -12.719 1.00 27.16 ? 455 LYS B CB 1 ATOM 7602 C CG . LYS B 1 455 ? -2.620 -26.480 -11.604 1.00 28.20 ? 455 LYS B CG 1 ATOM 7603 C CD . LYS B 1 455 ? -1.859 -26.336 -10.302 1.00 30.15 ? 455 LYS B CD 1 ATOM 7604 C CE . LYS B 1 455 ? -2.489 -27.201 -9.214 1.00 31.51 ? 455 LYS B CE 1 ATOM 7605 N NZ . LYS B 1 455 ? -1.944 -26.875 -7.864 1.00 33.14 ? 455 LYS B NZ 1 ATOM 7606 N N . TYR B 1 456 ? -4.404 -23.726 -13.491 1.00 26.69 ? 456 TYR B N 1 ATOM 7607 C CA . TYR B 1 456 ? -5.687 -23.154 -13.070 1.00 26.49 ? 456 TYR B CA 1 ATOM 7608 C C . TYR B 1 456 ? -6.598 -22.724 -14.221 1.00 26.62 ? 456 TYR B C 1 ATOM 7609 O O . TYR B 1 456 ? -7.625 -22.074 -13.993 1.00 26.42 ? 456 TYR B O 1 ATOM 7610 C CB . TYR B 1 456 ? -5.492 -22.006 -12.071 1.00 26.02 ? 456 TYR B CB 1 ATOM 7611 C CG . TYR B 1 456 ? -4.760 -22.414 -10.815 1.00 25.26 ? 456 TYR B CG 1 ATOM 7612 C CD1 . TYR B 1 456 ? -5.325 -23.312 -9.913 1.00 24.07 ? 456 TYR B CD1 1 ATOM 7613 C CD2 . TYR B 1 456 ? -3.500 -21.898 -10.527 1.00 23.86 ? 456 TYR B CD2 1 ATOM 7614 C CE1 . TYR B 1 456 ? -4.647 -23.686 -8.760 1.00 23.96 ? 456 TYR B CE1 1 ATOM 7615 C CE2 . TYR B 1 456 ? -2.822 -22.265 -9.388 1.00 23.50 ? 456 TYR B CE2 1 ATOM 7616 C CZ . TYR B 1 456 ? -3.395 -23.160 -8.511 1.00 23.87 ? 456 TYR B CZ 1 ATOM 7617 O OH . TYR B 1 456 ? -2.712 -23.521 -7.372 1.00 25.01 ? 456 TYR B OH 1 ATOM 7618 N N . SER B 1 457 ? -6.232 -23.091 -15.448 1.00 26.88 ? 457 SER B N 1 ATOM 7619 C CA . SER B 1 457 ? -7.108 -22.847 -16.599 1.00 27.23 ? 457 SER B CA 1 ATOM 7620 C C . SER B 1 457 ? -8.272 -23.837 -16.552 1.00 27.67 ? 457 SER B C 1 ATOM 7621 O O . SER B 1 457 ? -8.254 -24.788 -15.757 1.00 27.40 ? 457 SER B O 1 ATOM 7622 C CB . SER B 1 457 ? -6.338 -22.973 -17.917 1.00 27.15 ? 457 SER B CB 1 ATOM 7623 O OG . SER B 1 457 ? -5.926 -24.312 -18.136 1.00 26.42 ? 457 SER B OG 1 ATOM 7624 N N . THR B 1 458 ? -9.278 -23.622 -17.398 1.00 28.44 ? 458 THR B N 1 ATOM 7625 C CA . THR B 1 458 ? -10.468 -24.487 -17.394 1.00 29.13 ? 458 THR B CA 1 ATOM 7626 C C . THR B 1 458 ? -10.399 -25.606 -18.445 1.00 29.93 ? 458 THR B C 1 ATOM 7627 O O . THR B 1 458 ? -11.390 -26.299 -18.699 1.00 30.47 ? 458 THR B O 1 ATOM 7628 C CB . THR B 1 458 ? -11.785 -23.672 -17.516 1.00 28.88 ? 458 THR B CB 1 ATOM 7629 O OG1 . THR B 1 458 ? -11.930 -23.168 -18.846 1.00 28.91 ? 458 THR B OG1 1 ATOM 7630 C CG2 . THR B 1 458 ? -11.786 -22.510 -16.545 1.00 28.20 ? 458 THR B CG2 1 ATOM 7631 N N . LEU B 1 459 ? -9.222 -25.791 -19.036 1.00 30.59 ? 459 LEU B N 1 ATOM 7632 C CA . LEU B 1 459 ? -8.996 -26.881 -19.983 1.00 31.35 ? 459 LEU B CA 1 ATOM 7633 C C . LEU B 1 459 ? -9.166 -28.247 -19.325 1.00 32.40 ? 459 LEU B C 1 ATOM 7634 O O . LEU B 1 459 ? -9.045 -28.372 -18.105 1.00 32.51 ? 459 LEU B O 1 ATOM 7635 C CB . LEU B 1 459 ? -7.592 -26.779 -20.589 1.00 30.89 ? 459 LEU B CB 1 ATOM 7636 C CG . LEU B 1 459 ? -7.299 -25.544 -21.442 1.00 29.79 ? 459 LEU B CG 1 ATOM 7637 C CD1 . LEU B 1 459 ? -5.819 -25.515 -21.804 1.00 28.06 ? 459 LEU B CD1 1 ATOM 7638 C CD2 . LEU B 1 459 ? -8.189 -25.499 -22.690 1.00 27.26 ? 459 LEU B CD2 1 ATOM 7639 N N . LEU B 1 460 ? -9.451 -29.264 -20.141 1.00 33.70 ? 460 LEU B N 1 ATOM 7640 C CA . LEU B 1 460 ? -9.448 -30.655 -19.691 1.00 34.91 ? 460 LEU B CA 1 ATOM 7641 C C . LEU B 1 460 ? -8.039 -31.073 -19.280 1.00 35.71 ? 460 LEU B C 1 ATOM 7642 O O . LEU B 1 460 ? -7.055 -30.549 -19.803 1.00 35.89 ? 460 LEU B O 1 ATOM 7643 C CB . LEU B 1 460 ? -9.952 -31.579 -20.801 1.00 35.06 ? 460 LEU B CB 1 ATOM 7644 C CG . LEU B 1 460 ? -11.399 -31.440 -21.279 1.00 35.05 ? 460 LEU B CG 1 ATOM 7645 C CD1 . LEU B 1 460 ? -11.543 -32.154 -22.598 1.00 34.63 ? 460 LEU B CD1 1 ATOM 7646 C CD2 . LEU B 1 460 ? -12.397 -31.983 -20.248 1.00 34.50 ? 460 LEU B CD2 1 ATOM 7647 N N . GLU B 1 461 ? -7.943 -32.022 -18.355 1.00 36.81 ? 461 GLU B N 1 ATOM 7648 C CA . GLU B 1 461 ? -6.642 -32.461 -17.852 1.00 38.25 ? 461 GLU B CA 1 ATOM 7649 C C . GLU B 1 461 ? -5.686 -32.957 -18.950 1.00 38.42 ? 461 GLU B C 1 ATOM 7650 O O . GLU B 1 461 ? -4.479 -32.714 -18.874 1.00 38.78 ? 461 GLU B O 1 ATOM 7651 C CB . GLU B 1 461 ? -6.810 -33.511 -16.754 1.00 38.74 ? 461 GLU B CB 1 ATOM 7652 C CG . GLU B 1 461 ? -7.529 -32.998 -15.503 1.00 41.92 ? 461 GLU B CG 1 ATOM 7653 C CD . GLU B 1 461 ? -6.739 -31.935 -14.732 1.00 46.54 ? 461 GLU B CD 1 ATOM 7654 O OE1 . GLU B 1 461 ? -5.515 -32.120 -14.506 1.00 48.00 ? 461 GLU B OE1 1 ATOM 7655 O OE2 . GLU B 1 461 ? -7.352 -30.918 -14.339 1.00 48.10 ? 461 GLU B OE2 1 ATOM 7656 N N . SER B 1 462 ? -6.229 -33.628 -19.966 1.00 38.49 ? 462 SER B N 1 ATOM 7657 C CA . SER B 1 462 ? -5.441 -34.090 -21.107 1.00 38.69 ? 462 SER B CA 1 ATOM 7658 C C . SER B 1 462 ? -4.997 -32.932 -22.004 1.00 38.81 ? 462 SER B C 1 ATOM 7659 O O . SER B 1 462 ? -3.919 -32.985 -22.610 1.00 39.07 ? 462 SER B O 1 ATOM 7660 C CB . SER B 1 462 ? -6.235 -35.108 -21.925 1.00 38.73 ? 462 SER B CB 1 ATOM 7661 O OG . SER B 1 462 ? -7.484 -34.566 -22.318 1.00 39.57 ? 462 SER B OG 1 ATOM 7662 N N . GLU B 1 463 ? -5.835 -31.898 -22.095 1.00 38.74 ? 463 GLU B N 1 ATOM 7663 C CA . GLU B 1 463 ? -5.483 -30.670 -22.814 1.00 38.60 ? 463 GLU B CA 1 ATOM 7664 C C . GLU B 1 463 ? -4.412 -29.903 -22.047 1.00 38.02 ? 463 GLU B C 1 ATOM 7665 O O . GLU B 1 463 ? -3.541 -29.280 -22.653 1.00 37.87 ? 463 GLU B O 1 ATOM 7666 C CB . GLU B 1 463 ? -6.716 -29.795 -23.051 1.00 38.90 ? 463 GLU B CB 1 ATOM 7667 C CG . GLU B 1 463 ? -7.653 -30.332 -24.130 1.00 40.47 ? 463 GLU B CG 1 ATOM 7668 C CD . GLU B 1 463 ? -9.073 -29.766 -24.055 1.00 43.33 ? 463 GLU B CD 1 ATOM 7669 O OE1 . GLU B 1 463 ? -9.451 -29.147 -23.029 1.00 44.41 ? 463 GLU B OE1 1 ATOM 7670 O OE2 . GLU B 1 463 ? -9.825 -29.962 -25.030 1.00 44.25 ? 463 GLU B OE2 1 ATOM 7671 N N . LYS B 1 464 ? -4.466 -29.971 -20.719 1.00 37.39 ? 464 LYS B N 1 ATOM 7672 C CA . LYS B 1 464 ? -3.436 -29.352 -19.880 1.00 37.02 ? 464 LYS B CA 1 ATOM 7673 C C . LYS B 1 464 ? -2.058 -29.974 -20.107 1.00 37.15 ? 464 LYS B C 1 ATOM 7674 O O . LYS B 1 464 ? -1.059 -29.252 -20.173 1.00 36.71 ? 464 LYS B O 1 ATOM 7675 C CB . LYS B 1 464 ? -3.817 -29.407 -18.396 1.00 36.72 ? 464 LYS B CB 1 ATOM 7676 C CG . LYS B 1 464 ? -4.892 -28.416 -18.005 1.00 35.50 ? 464 LYS B CG 1 ATOM 7677 C CD . LYS B 1 464 ? -5.171 -28.461 -16.519 1.00 34.57 ? 464 LYS B CD 1 ATOM 7678 C CE . LYS B 1 464 ? -6.475 -27.767 -16.199 1.00 34.88 ? 464 LYS B CE 1 ATOM 7679 N NZ . LYS B 1 464 ? -6.746 -27.761 -14.738 1.00 35.16 ? 464 LYS B NZ 1 ATOM 7680 N N . ASN B 1 465 ? -2.021 -31.305 -20.236 1.00 37.37 ? 465 ASN B N 1 ATOM 7681 C CA . ASN B 1 465 ? -0.781 -32.029 -20.547 1.00 37.84 ? 465 ASN B CA 1 ATOM 7682 C C . ASN B 1 465 ? -0.160 -31.591 -21.863 1.00 37.63 ? 465 ASN B C 1 ATOM 7683 O O . ASN B 1 465 ? 1.046 -31.327 -21.928 1.00 37.65 ? 465 ASN B O 1 ATOM 7684 C CB . ASN B 1 465 ? -1.008 -33.540 -20.593 1.00 38.16 ? 465 ASN B CB 1 ATOM 7685 C CG . ASN B 1 465 ? -1.523 -34.092 -19.288 1.00 39.78 ? 465 ASN B CG 1 ATOM 7686 O OD1 . ASN B 1 465 ? -1.046 -33.732 -18.209 1.00 41.93 ? 465 ASN B OD1 1 ATOM 7687 N ND2 . ASN B 1 465 ? -2.510 -34.977 -19.377 1.00 41.91 ? 465 ASN B ND2 1 ATOM 7688 N N . THR B 1 466 ? -0.989 -31.529 -22.905 1.00 37.41 ? 466 THR B N 1 ATOM 7689 C CA . THR B 1 466 ? -0.555 -31.104 -24.233 1.00 37.34 ? 466 THR B CA 1 ATOM 7690 C C . THR B 1 466 ? -0.005 -29.679 -24.179 1.00 37.50 ? 466 THR B C 1 ATOM 7691 O O . THR B 1 466 ? 0.995 -29.362 -24.830 1.00 37.46 ? 466 THR B O 1 ATOM 7692 C CB . THR B 1 466 ? -1.722 -31.161 -25.237 1.00 37.30 ? 466 THR B CB 1 ATOM 7693 O OG1 . THR B 1 466 ? -2.333 -32.456 -25.193 1.00 37.68 ? 466 THR B OG1 1 ATOM 7694 C CG2 . THR B 1 466 ? -1.248 -30.869 -26.656 1.00 37.08 ? 466 THR B CG2 1 ATOM 7695 N N . PHE B 1 467 ? -0.678 -28.829 -23.401 1.00 37.72 ? 467 PHE B N 1 ATOM 7696 C CA . PHE B 1 467 ? -0.284 -27.439 -23.191 1.00 37.84 ? 467 PHE B CA 1 ATOM 7697 C C . PHE B 1 467 ? 1.062 -27.402 -22.476 1.00 38.15 ? 467 PHE B C 1 ATOM 7698 O O . PHE B 1 467 ? 1.964 -26.652 -22.872 1.00 37.97 ? 467 PHE B O 1 ATOM 7699 C CB . PHE B 1 467 ? -1.349 -26.725 -22.349 1.00 37.84 ? 467 PHE B CB 1 ATOM 7700 C CG . PHE B 1 467 ? -1.290 -25.211 -22.402 1.00 37.91 ? 467 PHE B CG 1 ATOM 7701 C CD1 . PHE B 1 467 ? -0.190 -24.534 -22.930 1.00 37.76 ? 467 PHE B CD1 1 ATOM 7702 C CD2 . PHE B 1 467 ? -2.339 -24.461 -21.880 1.00 38.32 ? 467 PHE B CD2 1 ATOM 7703 C CE1 . PHE B 1 467 ? -0.145 -23.152 -22.955 1.00 36.96 ? 467 PHE B CE1 1 ATOM 7704 C CE2 . PHE B 1 467 ? -2.300 -23.073 -21.902 1.00 37.68 ? 467 PHE B CE2 1 ATOM 7705 C CZ . PHE B 1 467 ? -1.200 -22.420 -22.442 1.00 37.53 ? 467 PHE B CZ 1 ATOM 7706 N N . MET B 1 468 ? 1.201 -28.222 -21.435 1.00 38.55 ? 468 MET B N 1 ATOM 7707 C CA . MET B 1 468 ? 2.451 -28.294 -20.687 1.00 39.39 ? 468 MET B CA 1 ATOM 7708 C C . MET B 1 468 ? 3.611 -28.720 -21.591 1.00 39.57 ? 468 MET B C 1 ATOM 7709 O O . MET B 1 468 ? 4.700 -28.133 -21.535 1.00 39.64 ? 468 MET B O 1 ATOM 7710 C CB . MET B 1 468 ? 2.316 -29.237 -19.492 1.00 39.62 ? 468 MET B CB 1 ATOM 7711 C CG . MET B 1 468 ? 3.426 -29.077 -18.459 1.00 41.59 ? 468 MET B CG 1 ATOM 7712 S SD . MET B 1 468 ? 3.339 -27.500 -17.577 1.00 45.35 ? 468 MET B SD 1 ATOM 7713 C CE . MET B 1 468 ? 2.242 -27.911 -16.226 1.00 44.77 ? 468 MET B CE 1 ATOM 7714 N N . GLU B 1 469 ? 3.348 -29.724 -22.431 1.00 39.65 ? 469 GLU B N 1 ATOM 7715 C CA . GLU B 1 469 ? 4.301 -30.248 -23.407 1.00 39.68 ? 469 GLU B CA 1 ATOM 7716 C C . GLU B 1 469 ? 4.813 -29.152 -24.333 1.00 38.66 ? 469 GLU B C 1 ATOM 7717 O O . GLU B 1 469 ? 6.026 -28.988 -24.502 1.00 38.67 ? 469 GLU B O 1 ATOM 7718 C CB . GLU B 1 469 ? 3.627 -31.323 -24.253 1.00 40.20 ? 469 GLU B CB 1 ATOM 7719 C CG . GLU B 1 469 ? 4.408 -32.607 -24.372 1.00 44.09 ? 469 GLU B CG 1 ATOM 7720 C CD . GLU B 1 469 ? 3.985 -33.606 -23.323 1.00 48.95 ? 469 GLU B CD 1 ATOM 7721 O OE1 . GLU B 1 469 ? 3.087 -34.425 -23.629 1.00 50.84 ? 469 GLU B OE1 1 ATOM 7722 O OE2 . GLU B 1 469 ? 4.525 -33.549 -22.193 1.00 50.56 ? 469 GLU B OE2 1 ATOM 7723 N N . ILE B 1 470 ? 3.876 -28.411 -24.925 1.00 37.48 ? 470 ILE B N 1 ATOM 7724 C CA . ILE B 1 470 ? 4.187 -27.303 -25.827 1.00 36.54 ? 470 ILE B CA 1 ATOM 7725 C C . ILE B 1 470 ? 4.969 -26.198 -25.107 1.00 36.28 ? 470 ILE B C 1 ATOM 7726 O O . ILE B 1 470 ? 5.987 -25.708 -25.614 1.00 36.34 ? 470 ILE B O 1 ATOM 7727 C CB . ILE B 1 470 ? 2.899 -26.742 -26.485 1.00 36.32 ? 470 ILE B CB 1 ATOM 7728 C CG1 . ILE B 1 470 ? 2.306 -27.777 -27.447 1.00 35.93 ? 470 ILE B CG1 1 ATOM 7729 C CG2 . ILE B 1 470 ? 3.174 -25.425 -27.209 1.00 35.77 ? 470 ILE B CG2 1 ATOM 7730 C CD1 . ILE B 1 470 ? 0.896 -27.466 -27.915 1.00 35.10 ? 470 ILE B CD1 1 ATOM 7731 N N . TRP B 1 471 ? 4.499 -25.834 -23.915 1.00 35.72 ? 471 TRP B N 1 ATOM 7732 C CA . TRP B 1 471 ? 5.137 -24.798 -23.109 1.00 35.30 ? 471 TRP B CA 1 ATOM 7733 C C . TRP B 1 471 ? 6.565 -25.172 -22.658 1.00 35.86 ? 471 TRP B C 1 ATOM 7734 O O . TRP B 1 471 ? 7.468 -24.329 -22.694 1.00 35.80 ? 471 TRP B O 1 ATOM 7735 C CB . TRP B 1 471 ? 4.255 -24.409 -21.904 1.00 34.61 ? 471 TRP B CB 1 ATOM 7736 C CG . TRP B 1 471 ? 4.944 -23.478 -20.970 1.00 32.29 ? 471 TRP B CG 1 ATOM 7737 C CD1 . TRP B 1 471 ? 4.952 -22.113 -21.025 1.00 30.98 ? 471 TRP B CD1 1 ATOM 7738 C CD2 . TRP B 1 471 ? 5.775 -23.841 -19.862 1.00 30.72 ? 471 TRP B CD2 1 ATOM 7739 N NE1 . TRP B 1 471 ? 5.722 -21.603 -20.008 1.00 30.18 ? 471 TRP B NE1 1 ATOM 7740 C CE2 . TRP B 1 471 ? 6.239 -22.642 -19.279 1.00 30.22 ? 471 TRP B CE2 1 ATOM 7741 C CE3 . TRP B 1 471 ? 6.164 -25.065 -19.297 1.00 30.01 ? 471 TRP B CE3 1 ATOM 7742 C CZ2 . TRP B 1 471 ? 7.078 -22.629 -18.166 1.00 29.98 ? 471 TRP B CZ2 1 ATOM 7743 C CZ3 . TRP B 1 471 ? 6.996 -25.051 -18.188 1.00 29.87 ? 471 TRP B CZ3 1 ATOM 7744 C CH2 . TRP B 1 471 ? 7.445 -23.840 -17.636 1.00 30.51 ? 471 TRP B CH2 1 ATOM 7745 N N . LYS B 1 472 ? 6.761 -26.423 -22.234 1.00 36.47 ? 472 LYS B N 1 ATOM 7746 C CA . LYS B 1 472 ? 8.079 -26.895 -21.790 1.00 37.13 ? 472 LYS B CA 1 ATOM 7747 C C . LYS B 1 472 ? 9.152 -26.697 -22.872 1.00 37.24 ? 472 LYS B C 1 ATOM 7748 O O . LYS B 1 472 ? 10.270 -26.262 -22.577 1.00 37.10 ? 472 LYS B O 1 ATOM 7749 C CB . LYS B 1 472 ? 8.005 -28.360 -21.330 1.00 37.22 ? 472 LYS B CB 1 ATOM 7750 C CG . LYS B 1 472 ? 9.270 -28.906 -20.666 1.00 39.12 ? 472 LYS B CG 1 ATOM 7751 C CD . LYS B 1 472 ? 9.633 -28.158 -19.370 1.00 42.88 ? 472 LYS B CD 1 ATOM 7752 C CE . LYS B 1 472 ? 10.933 -28.677 -18.729 1.00 44.43 ? 472 LYS B CE 1 ATOM 7753 N NZ . LYS B 1 472 ? 12.147 -28.483 -19.589 1.00 44.90 ? 472 LYS B NZ 1 ATOM 7754 N N . LYS B 1 473 ? 8.793 -26.993 -24.120 1.00 37.50 ? 473 LYS B N 1 ATOM 7755 C CA . LYS B 1 473 ? 9.706 -26.848 -25.247 1.00 38.01 ? 473 LYS B CA 1 ATOM 7756 C C . LYS B 1 473 ? 10.036 -25.385 -25.536 1.00 37.71 ? 473 LYS B C 1 ATOM 7757 O O . LYS B 1 473 ? 11.187 -25.055 -25.847 1.00 37.88 ? 473 LYS B O 1 ATOM 7758 C CB . LYS B 1 473 ? 9.132 -27.516 -26.497 1.00 38.32 ? 473 LYS B CB 1 ATOM 7759 C CG . LYS B 1 473 ? 9.451 -28.979 -26.629 1.00 40.54 ? 473 LYS B CG 1 ATOM 7760 C CD . LYS B 1 473 ? 9.187 -29.425 -28.050 1.00 46.02 ? 473 LYS B CD 1 ATOM 7761 C CE . LYS B 1 473 ? 10.325 -30.280 -28.586 1.00 48.54 ? 473 LYS B CE 1 ATOM 7762 N NZ . LYS B 1 473 ? 10.101 -31.728 -28.343 1.00 50.46 ? 473 LYS B NZ 1 ATOM 7763 N N . ARG B 1 474 ? 9.033 -24.511 -25.438 1.00 37.26 ? 474 ARG B N 1 ATOM 7764 C CA . ARG B 1 474 ? 9.270 -23.065 -25.552 1.00 36.69 ? 474 ARG B CA 1 ATOM 7765 C C . ARG B 1 474 ? 10.107 -22.546 -24.378 1.00 36.42 ? 474 ARG B C 1 ATOM 7766 O O . ARG B 1 474 ? 10.900 -21.609 -24.536 1.00 36.19 ? 474 ARG B O 1 ATOM 7767 C CB . ARG B 1 474 ? 7.962 -22.293 -25.661 1.00 36.57 ? 474 ARG B CB 1 ATOM 7768 C CG . ARG B 1 474 ? 7.278 -22.432 -27.005 1.00 36.16 ? 474 ARG B CG 1 ATOM 7769 C CD . ARG B 1 474 ? 6.398 -21.236 -27.272 1.00 36.49 ? 474 ARG B CD 1 ATOM 7770 N NE . ARG B 1 474 ? 5.872 -21.236 -28.631 1.00 36.80 ? 474 ARG B NE 1 ATOM 7771 C CZ . ARG B 1 474 ? 5.540 -20.141 -29.312 1.00 36.84 ? 474 ARG B CZ 1 ATOM 7772 N NH1 . ARG B 1 474 ? 5.686 -18.944 -28.768 1.00 36.27 ? 474 ARG B NH1 1 ATOM 7773 N NH2 . ARG B 1 474 ? 5.065 -20.239 -30.550 1.00 37.60 ? 474 ARG B NH2 1 ATOM 7774 N N . TRP B 1 475 ? 9.939 -23.181 -23.217 1.00 35.95 ? 475 TRP B N 1 ATOM 7775 C CA . TRP B 1 475 ? 10.700 -22.841 -22.018 1.00 35.94 ? 475 TRP B CA 1 ATOM 7776 C C . TRP B 1 475 ? 12.195 -23.165 -22.174 1.00 36.05 ? 475 TRP B C 1 ATOM 7777 O O . TRP B 1 475 ? 13.046 -22.307 -21.945 1.00 36.31 ? 475 TRP B O 1 ATOM 7778 C CB . TRP B 1 475 ? 10.091 -23.513 -20.777 1.00 35.70 ? 475 TRP B CB 1 ATOM 7779 C CG . TRP B 1 475 ? 10.825 -23.231 -19.509 1.00 35.46 ? 475 TRP B CG 1 ATOM 7780 C CD1 . TRP B 1 475 ? 11.722 -24.050 -18.884 1.00 36.13 ? 475 TRP B CD1 1 ATOM 7781 C CD2 . TRP B 1 475 ? 10.734 -22.048 -18.703 1.00 35.34 ? 475 TRP B CD2 1 ATOM 7782 N NE1 . TRP B 1 475 ? 12.197 -23.454 -17.737 1.00 36.29 ? 475 TRP B NE1 1 ATOM 7783 C CE2 . TRP B 1 475 ? 11.608 -22.225 -17.600 1.00 35.72 ? 475 TRP B CE2 1 ATOM 7784 C CE3 . TRP B 1 475 ? 10.001 -20.858 -18.801 1.00 34.81 ? 475 TRP B CE3 1 ATOM 7785 C CZ2 . TRP B 1 475 ? 11.770 -21.253 -16.605 1.00 35.26 ? 475 TRP B CZ2 1 ATOM 7786 C CZ3 . TRP B 1 475 ? 10.159 -19.893 -17.812 1.00 34.79 ? 475 TRP B CZ3 1 ATOM 7787 C CH2 . TRP B 1 475 ? 11.038 -20.096 -16.728 1.00 34.92 ? 475 TRP B CH2 1 ATOM 7788 N N . ASP B 1 476 ? 12.509 -24.391 -22.580 1.00 36.22 ? 476 ASP B N 1 ATOM 7789 C CA . ASP B 1 476 ? 13.895 -24.779 -22.849 1.00 36.40 ? 476 ASP B CA 1 ATOM 7790 C C . ASP B 1 476 ? 14.612 -23.842 -23.826 1.00 36.22 ? 476 ASP B C 1 ATOM 7791 O O . ASP B 1 476 ? 15.749 -23.440 -23.577 1.00 35.98 ? 476 ASP B O 1 ATOM 7792 C CB . ASP B 1 476 ? 13.939 -26.215 -23.341 1.00 36.50 ? 476 ASP B CB 1 ATOM 7793 C CG . ASP B 1 476 ? 13.375 -27.171 -22.328 1.00 37.55 ? 476 ASP B CG 1 ATOM 7794 O OD1 . ASP B 1 476 ? 13.486 -26.868 -21.120 1.00 39.19 ? 476 ASP B OD1 1 ATOM 7795 O OD2 . ASP B 1 476 ? 12.812 -28.214 -22.728 1.00 39.71 ? 476 ASP B OD2 1 ATOM 7796 N N . LYS B 1 477 ? 13.929 -23.489 -24.915 1.00 36.19 ? 477 LYS B N 1 ATOM 7797 C CA . LYS B 1 477 ? 14.444 -22.547 -25.912 1.00 36.43 ? 477 LYS B CA 1 ATOM 7798 C C . LYS B 1 477 ? 14.743 -21.187 -25.293 1.00 36.22 ? 477 LYS B C 1 ATOM 7799 O O . LYS B 1 477 ? 15.754 -20.553 -25.614 1.00 36.54 ? 477 LYS B O 1 ATOM 7800 C CB . LYS B 1 477 ? 13.439 -22.381 -27.067 1.00 36.89 ? 477 LYS B CB 1 ATOM 7801 C CG . LYS B 1 477 ? 13.696 -21.185 -28.011 1.00 38.08 ? 477 LYS B CG 1 ATOM 7802 C CD . LYS B 1 477 ? 14.893 -21.449 -28.904 1.00 41.71 ? 477 LYS B CD 1 ATOM 7803 C CE . LYS B 1 477 ? 15.605 -20.170 -29.360 1.00 43.86 ? 477 LYS B CE 1 ATOM 7804 N NZ . LYS B 1 477 ? 14.885 -19.434 -30.443 1.00 44.42 ? 477 LYS B NZ 1 ATOM 7805 N N . PHE B 1 478 ? 13.845 -20.743 -24.417 1.00 35.82 ? 478 PHE B N 1 ATOM 7806 C CA . PHE B 1 478 ? 13.994 -19.487 -23.697 1.00 35.24 ? 478 PHE B CA 1 ATOM 7807 C C . PHE B 1 478 ? 15.205 -19.557 -22.760 1.00 35.35 ? 478 PHE B C 1 ATOM 7808 O O . PHE B 1 478 ? 16.042 -18.653 -22.764 1.00 35.22 ? 478 PHE B O 1 ATOM 7809 C CB . PHE B 1 478 ? 12.691 -19.184 -22.941 1.00 34.89 ? 478 PHE B CB 1 ATOM 7810 C CG . PHE B 1 478 ? 12.801 -18.079 -21.930 1.00 33.81 ? 478 PHE B CG 1 ATOM 7811 C CD1 . PHE B 1 478 ? 12.836 -16.746 -22.328 1.00 32.49 ? 478 PHE B CD1 1 ATOM 7812 C CD2 . PHE B 1 478 ? 12.837 -18.374 -20.568 1.00 32.85 ? 478 PHE B CD2 1 ATOM 7813 C CE1 . PHE B 1 478 ? 12.926 -15.727 -21.378 1.00 32.17 ? 478 PHE B CE1 1 ATOM 7814 C CE2 . PHE B 1 478 ? 12.926 -17.358 -19.615 1.00 31.37 ? 478 PHE B CE2 1 ATOM 7815 C CZ . PHE B 1 478 ? 12.972 -16.038 -20.021 1.00 31.35 ? 478 PHE B CZ 1 ATOM 7816 N N . ILE B 1 479 ? 15.294 -20.635 -21.978 1.00 35.57 ? 479 ILE B N 1 ATOM 7817 C CA . ILE B 1 479 ? 16.428 -20.875 -21.070 1.00 36.05 ? 479 ILE B CA 1 ATOM 7818 C C . ILE B 1 479 ? 17.784 -20.780 -21.791 1.00 36.66 ? 479 ILE B C 1 ATOM 7819 O O . ILE B 1 479 ? 18.692 -20.070 -21.335 1.00 36.60 ? 479 ILE B O 1 ATOM 7820 C CB . ILE B 1 479 ? 16.309 -22.246 -20.349 1.00 35.76 ? 479 ILE B CB 1 ATOM 7821 C CG1 . ILE B 1 479 ? 15.073 -22.299 -19.437 1.00 35.94 ? 479 ILE B CG1 1 ATOM 7822 C CG2 . ILE B 1 479 ? 17.569 -22.563 -19.566 1.00 35.43 ? 479 ILE B CG2 1 ATOM 7823 C CD1 . ILE B 1 479 ? 14.906 -21.098 -18.475 1.00 35.41 ? 479 ILE B CD1 1 ATOM 7824 N N . ALA B 1 480 ? 17.896 -21.483 -22.920 1.00 37.32 ? 480 ALA B N 1 ATOM 7825 C CA . ALA B 1 480 ? 19.118 -21.517 -23.725 1.00 37.97 ? 480 ALA B CA 1 ATOM 7826 C C . ALA B 1 480 ? 19.506 -20.138 -24.261 1.00 38.50 ? 480 ALA B C 1 ATOM 7827 O O . ALA B 1 480 ? 20.690 -19.790 -24.283 1.00 38.71 ? 480 ALA B O 1 ATOM 7828 C CB . ALA B 1 480 ? 18.971 -22.512 -24.866 1.00 37.84 ? 480 ALA B CB 1 ATOM 7829 N N . ASP B 1 481 ? 18.515 -19.356 -24.684 1.00 39.12 ? 481 ASP B N 1 ATOM 7830 C CA . ASP B 1 481 ? 18.752 -17.973 -25.109 1.00 40.00 ? 481 ASP B CA 1 ATOM 7831 C C . ASP B 1 481 ? 19.331 -17.098 -23.996 1.00 40.05 ? 481 ASP B C 1 ATOM 7832 O O . ASP B 1 481 ? 20.353 -16.442 -24.185 1.00 40.33 ? 481 ASP B O 1 ATOM 7833 C CB . ASP B 1 481 ? 17.468 -17.328 -25.628 1.00 40.35 ? 481 ASP B CB 1 ATOM 7834 C CG . ASP B 1 481 ? 17.103 -17.777 -27.034 1.00 42.54 ? 481 ASP B CG 1 ATOM 7835 O OD1 . ASP B 1 481 ? 17.983 -18.286 -27.773 1.00 44.74 ? 481 ASP B OD1 1 ATOM 7836 O OD2 . ASP B 1 481 ? 15.921 -17.606 -27.403 1.00 44.39 ? 481 ASP B OD2 1 ATOM 7837 N N . VAL B 1 482 ? 18.671 -17.092 -22.839 1.00 40.10 ? 482 VAL B N 1 ATOM 7838 C CA . VAL B 1 482 ? 19.067 -16.238 -21.722 1.00 40.01 ? 482 VAL B CA 1 ATOM 7839 C C . VAL B 1 482 ? 20.425 -16.673 -21.168 1.00 40.33 ? 482 VAL B C 1 ATOM 7840 O O . VAL B 1 482 ? 21.242 -15.834 -20.786 1.00 39.97 ? 482 VAL B O 1 ATOM 7841 C CB . VAL B 1 482 ? 17.985 -16.219 -20.608 1.00 40.03 ? 482 VAL B CB 1 ATOM 7842 C CG1 . VAL B 1 482 ? 18.418 -15.350 -19.437 1.00 39.79 ? 482 VAL B CG1 1 ATOM 7843 C CG2 . VAL B 1 482 ? 16.647 -15.729 -21.168 1.00 39.09 ? 482 VAL B CG2 1 ATOM 7844 N N . ALA B 1 483 ? 20.663 -17.987 -21.150 1.00 40.92 ? 483 ALA B N 1 ATOM 7845 C CA . ALA B 1 483 ? 21.956 -18.540 -20.753 1.00 41.52 ? 483 ALA B CA 1 ATOM 7846 C C . ALA B 1 483 ? 23.097 -18.098 -21.688 1.00 42.10 ? 483 ALA B C 1 ATOM 7847 O O . ALA B 1 483 ? 24.264 -18.123 -21.291 1.00 42.31 ? 483 ALA B O 1 ATOM 7848 C CB . ALA B 1 483 ? 21.888 -20.057 -20.648 1.00 41.41 ? 483 ALA B CB 1 ATOM 7849 N N . THR B 1 484 ? 22.760 -17.683 -22.912 1.00 42.61 ? 484 THR B N 1 ATOM 7850 C CA . THR B 1 484 ? 23.732 -17.027 -23.793 1.00 43.18 ? 484 THR B CA 1 ATOM 7851 C C . THR B 1 484 ? 23.214 -15.676 -24.308 1.00 43.29 ? 484 THR B C 1 ATOM 7852 O O . THR B 1 484 ? 23.108 -15.439 -25.512 1.00 43.38 ? 484 THR B O 1 ATOM 7853 C CB . THR B 1 484 ? 24.167 -17.925 -24.955 1.00 43.37 ? 484 THR B CB 1 ATOM 7854 O OG1 . THR B 1 484 ? 24.014 -19.304 -24.581 1.00 43.88 ? 484 THR B OG1 1 ATOM 7855 C CG2 . THR B 1 484 ? 25.629 -17.629 -25.318 1.00 43.90 ? 484 THR B CG2 1 HETATM 7856 C C1 . NAG C 2 . ? 6.654 30.812 27.762 1.00 51.91 ? 509 NAG A C1 1 HETATM 7857 C C2 . NAG C 2 . ? 5.581 31.629 28.488 1.00 53.72 ? 509 NAG A C2 1 HETATM 7858 C C3 . NAG C 2 . ? 5.743 31.568 30.011 1.00 53.86 ? 509 NAG A C3 1 HETATM 7859 C C4 . NAG C 2 . ? 6.015 30.141 30.481 1.00 53.57 ? 509 NAG A C4 1 HETATM 7860 C C5 . NAG C 2 . ? 7.239 29.607 29.723 1.00 53.43 ? 509 NAG A C5 1 HETATM 7861 C C6 . NAG C 2 . ? 7.697 28.229 30.199 1.00 53.35 ? 509 NAG A C6 1 HETATM 7862 C C7 . NAG C 2 . ? 4.666 33.793 27.728 1.00 54.66 ? 509 NAG A C7 1 HETATM 7863 C C8 . NAG C 2 . ? 5.026 35.169 27.247 1.00 54.73 ? 509 NAG A C8 1 HETATM 7864 N N2 . NAG C 2 . ? 5.698 32.998 28.018 1.00 54.17 ? 509 NAG A N2 1 HETATM 7865 O O3 . NAG C 2 . ? 4.583 32.055 30.641 1.00 54.71 ? 509 NAG A O3 1 HETATM 7866 O O4 . NAG C 2 . ? 6.200 30.128 31.878 1.00 53.67 ? 509 NAG A O4 1 HETATM 7867 O O5 . NAG C 2 . ? 6.921 29.551 28.343 1.00 52.30 ? 509 NAG A O5 1 HETATM 7868 O O6 . NAG C 2 . ? 7.041 27.213 29.472 1.00 52.34 ? 509 NAG A O6 1 HETATM 7869 O O7 . NAG C 2 . ? 3.484 33.465 27.838 1.00 54.38 ? 509 NAG A O7 1 HETATM 7870 C C1 . NAG D 2 . ? 12.453 28.420 5.027 1.00 62.95 ? 510 NAG A C1 1 HETATM 7871 C C2 . NAG D 2 . ? 11.036 28.733 4.527 1.00 66.74 ? 510 NAG A C2 1 HETATM 7872 C C3 . NAG D 2 . ? 11.066 29.902 3.548 1.00 66.79 ? 510 NAG A C3 1 HETATM 7873 C C4 . NAG D 2 . ? 11.526 31.145 4.304 1.00 66.59 ? 510 NAG A C4 1 HETATM 7874 C C5 . NAG D 2 . ? 12.892 30.942 4.978 1.00 65.77 ? 510 NAG A C5 1 HETATM 7875 C C6 . NAG D 2 . ? 13.046 31.890 6.182 1.00 65.42 ? 510 NAG A C6 1 HETATM 7876 C C7 . NAG D 2 . ? 9.169 27.189 4.213 1.00 69.48 ? 510 NAG A C7 1 HETATM 7877 C C8 . NAG D 2 . ? 8.660 25.948 3.536 1.00 69.66 ? 510 NAG A C8 1 HETATM 7878 N N2 . NAG D 2 . ? 10.422 27.552 3.933 1.00 68.36 ? 510 NAG A N2 1 HETATM 7879 O O3 . NAG D 2 . ? 9.789 30.110 2.986 1.00 67.81 ? 510 NAG A O3 1 HETATM 7880 O O4 . NAG D 2 . ? 11.626 32.253 3.431 1.00 67.28 ? 510 NAG A O4 1 HETATM 7881 O O5 . NAG D 2 . ? 13.232 29.593 5.360 1.00 64.72 ? 510 NAG A O5 1 HETATM 7882 O O6 . NAG D 2 . ? 11.842 32.578 6.481 1.00 65.05 ? 510 NAG A O6 1 HETATM 7883 O O7 . NAG D 2 . ? 8.443 27.823 4.981 1.00 70.17 ? 510 NAG A O7 1 HETATM 7884 C C1 . NAG E 2 . ? 21.212 -12.608 22.316 1.00 49.00 ? 511 NAG A C1 1 HETATM 7885 C C2 . NAG E 2 . ? 22.612 -12.049 22.582 1.00 51.09 ? 511 NAG A C2 1 HETATM 7886 C C3 . NAG E 2 . ? 23.663 -13.156 22.589 1.00 51.81 ? 511 NAG A C3 1 HETATM 7887 C C4 . NAG E 2 . ? 23.226 -14.341 23.456 1.00 52.68 ? 511 NAG A C4 1 HETATM 7888 C C5 . NAG E 2 . ? 21.804 -14.774 23.056 1.00 52.42 ? 511 NAG A C5 1 HETATM 7889 C C6 . NAG E 2 . ? 21.280 -15.992 23.814 1.00 52.56 ? 511 NAG A C6 1 HETATM 7890 C C7 . NAG E 2 . ? 23.028 -9.722 21.994 1.00 52.51 ? 511 NAG A C7 1 HETATM 7891 C C8 . NAG E 2 . ? 23.404 -8.737 20.927 1.00 52.54 ? 511 NAG A C8 1 HETATM 7892 N N2 . NAG E 2 . ? 22.964 -11.008 21.628 1.00 51.64 ? 511 NAG A N2 1 HETATM 7893 O O3 . NAG E 2 . ? 24.873 -12.630 23.081 1.00 52.20 ? 511 NAG A O3 1 HETATM 7894 O O4 . NAG E 2 . ? 24.169 -15.392 23.324 1.00 53.86 ? 511 NAG A O4 1 HETATM 7895 O O5 . NAG E 2 . ? 20.914 -13.673 23.213 1.00 50.92 ? 511 NAG A O5 1 HETATM 7896 O O6 . NAG E 2 . ? 21.184 -15.714 25.193 1.00 53.20 ? 511 NAG A O6 1 HETATM 7897 O O7 . NAG E 2 . ? 22.796 -9.315 23.138 1.00 52.71 ? 511 NAG A O7 1 HETATM 7898 ZN ZN . ZN F 3 . ? 11.302 6.936 14.949 1.00 42.55 ? 512 ZN A ZN 1 HETATM 7899 N N1 . CFE G 4 . ? 12.233 10.583 13.546 1.00 30.30 ? 513 CFE A N1 1 HETATM 7900 C C2 . CFE G 4 . ? 13.410 11.144 13.939 1.00 30.94 ? 513 CFE A C2 1 HETATM 7901 N N3 . CFE G 4 . ? 14.470 10.380 13.595 1.00 31.73 ? 513 CFE A N3 1 HETATM 7902 N N4 . CFE G 4 . ? 14.685 8.275 12.453 1.00 30.88 ? 513 CFE A N4 1 HETATM 7903 C C5 . CFE G 4 . ? 14.311 7.409 11.597 1.00 30.84 ? 513 CFE A C5 1 HETATM 7904 N N6 . CFE G 4 . ? 13.208 7.277 10.955 1.00 31.30 ? 513 CFE A N6 1 HETATM 7905 C C7 . CFE G 4 . ? 11.973 8.082 10.933 1.00 31.35 ? 513 CFE A C7 1 HETATM 7906 C C8 . CFE G 4 . ? 11.504 8.481 12.322 1.00 31.56 ? 513 CFE A C8 1 HETATM 7907 O O8 . CFE G 4 . ? 11.369 7.311 13.135 1.00 33.59 ? 513 CFE A O8 1 HETATM 7908 C C9 . CFE G 4 . ? 12.477 9.417 12.920 1.00 31.06 ? 513 CFE A C9 1 HETATM 7909 C C10 . CFE G 4 . ? 13.950 9.331 12.952 1.00 31.52 ? 513 CFE A C10 1 HETATM 7910 C C1S . CFE G 4 . ? 15.905 10.688 13.847 1.00 32.09 ? 513 CFE A C1S 1 HETATM 7911 C C2S . CFE G 4 . ? 16.357 11.728 12.832 1.00 31.67 ? 513 CFE A C2S 1 HETATM 7912 O O2S . CFE G 4 . ? 17.446 11.195 12.077 1.00 30.97 ? 513 CFE A O2S 1 HETATM 7913 C C3S . CFE G 4 . ? 16.756 12.956 13.640 1.00 32.63 ? 513 CFE A C3S 1 HETATM 7914 O O3S . CFE G 4 . ? 17.984 13.558 13.211 1.00 32.21 ? 513 CFE A O3S 1 HETATM 7915 C C4S . CFE G 4 . ? 16.896 12.445 15.062 1.00 33.51 ? 513 CFE A C4S 1 HETATM 7916 O O4S . CFE G 4 . ? 16.100 11.262 15.146 1.00 33.13 ? 513 CFE A O4S 1 HETATM 7917 C C5S . CFE G 4 . ? 16.433 13.472 16.082 1.00 34.47 ? 513 CFE A C5S 1 HETATM 7918 O O5S . CFE G 4 . ? 16.823 13.003 17.378 1.00 37.12 ? 513 CFE A O5S 1 HETATM 7919 C C1 . NAG H 2 . ? -6.379 -3.270 -41.541 1.00 54.49 ? 509 NAG B C1 1 HETATM 7920 C C2 . NAG H 2 . ? -6.338 -3.291 -43.077 1.00 57.60 ? 509 NAG B C2 1 HETATM 7921 C C3 . NAG H 2 . ? -6.376 -4.735 -43.595 1.00 57.97 ? 509 NAG B C3 1 HETATM 7922 C C4 . NAG H 2 . ? -5.943 -5.750 -42.539 1.00 57.49 ? 509 NAG B C4 1 HETATM 7923 C C5 . NAG H 2 . ? -6.808 -5.654 -41.278 1.00 56.74 ? 509 NAG B C5 1 HETATM 7924 C C6 . NAG H 2 . ? -6.103 -6.292 -40.083 1.00 56.14 ? 509 NAG B C6 1 HETATM 7925 C C7 . NAG H 2 . ? -7.560 -1.189 -43.736 1.00 59.22 ? 509 NAG B C7 1 HETATM 7926 C C8 . NAG H 2 . ? -8.794 -0.671 -44.425 1.00 59.21 ? 509 NAG B C8 1 HETATM 7927 N N2 . NAG H 2 . ? -7.431 -2.528 -43.682 1.00 58.43 ? 509 NAG B N2 1 HETATM 7928 O O3 . NAG H 2 . ? -5.524 -4.875 -44.708 1.00 59.42 ? 509 NAG B O3 1 HETATM 7929 O O4 . NAG H 2 . ? -6.030 -7.047 -43.087 1.00 57.98 ? 509 NAG B O4 1 HETATM 7930 O O5 . NAG H 2 . ? -7.180 -4.311 -40.987 1.00 55.59 ? 509 NAG B O5 1 HETATM 7931 O O6 . NAG H 2 . ? -6.986 -7.196 -39.462 1.00 55.55 ? 509 NAG B O6 1 HETATM 7932 O O7 . NAG H 2 . ? -6.759 -0.379 -43.267 1.00 59.01 ? 509 NAG B O7 1 HETATM 7933 C C1 . NAG I 2 . ? -12.674 12.474 -24.488 1.00 61.15 ? 510 NAG B C1 1 HETATM 7934 C C2 . NAG I 2 . ? -12.202 12.101 -23.051 1.00 63.79 ? 510 NAG B C2 1 HETATM 7935 C C3 . NAG I 2 . ? -13.139 12.627 -21.949 1.00 64.33 ? 510 NAG B C3 1 HETATM 7936 C C4 . NAG I 2 . ? -13.490 14.094 -22.184 1.00 64.81 ? 510 NAG B C4 1 HETATM 7937 C C5 . NAG I 2 . ? -14.012 14.223 -23.623 1.00 64.54 ? 510 NAG B C5 1 HETATM 7938 C C6 . NAG I 2 . ? -14.581 15.606 -23.927 1.00 65.23 ? 510 NAG B C6 1 HETATM 7939 C C7 . NAG I 2 . ? -10.861 10.145 -22.303 1.00 64.85 ? 510 NAG B C7 1 HETATM 7940 C C8 . NAG I 2 . ? -9.701 11.047 -21.979 1.00 64.98 ? 510 NAG B C8 1 HETATM 7941 N N2 . NAG I 2 . ? -11.990 10.676 -22.808 1.00 64.04 ? 510 NAG B N2 1 HETATM 7942 O O3 . NAG I 2 . ? -12.540 12.467 -20.678 1.00 64.67 ? 510 NAG B O3 1 HETATM 7943 O O4 . NAG I 2 . ? -14.430 14.527 -21.217 1.00 64.71 ? 510 NAG B O4 1 HETATM 7944 O O5 . NAG I 2 . ? -12.979 13.867 -24.544 1.00 63.50 ? 510 NAG B O5 1 HETATM 7945 O O6 . NAG I 2 . ? -15.873 15.686 -23.346 1.00 66.24 ? 510 NAG B O6 1 HETATM 7946 O O7 . NAG I 2 . ? -10.730 8.937 -22.102 1.00 65.31 ? 510 NAG B O7 1 HETATM 7947 C C1 . NAG J 2 . ? -21.329 -25.417 -3.825 1.00 48.66 ? 511 NAG B C1 1 HETATM 7948 C C2 . NAG J 2 . ? -22.680 -25.332 -4.549 1.00 50.82 ? 511 NAG B C2 1 HETATM 7949 C C3 . NAG J 2 . ? -23.781 -26.098 -3.811 1.00 51.53 ? 511 NAG B C3 1 HETATM 7950 C C4 . NAG J 2 . ? -23.307 -27.511 -3.445 1.00 51.83 ? 511 NAG B C4 1 HETATM 7951 C C5 . NAG J 2 . ? -21.977 -27.406 -2.684 1.00 51.77 ? 511 NAG B C5 1 HETATM 7952 C C6 . NAG J 2 . ? -21.454 -28.755 -2.183 1.00 51.72 ? 511 NAG B C6 1 HETATM 7953 C C7 . NAG J 2 . ? -23.140 -23.386 -5.942 1.00 52.32 ? 511 NAG B C7 1 HETATM 7954 C C8 . NAG J 2 . ? -23.604 -21.962 -5.978 1.00 52.72 ? 511 NAG B C8 1 HETATM 7955 N N2 . NAG J 2 . ? -23.103 -23.955 -4.738 1.00 51.48 ? 511 NAG B N2 1 HETATM 7956 O O3 . NAG J 2 . ? -24.936 -26.145 -4.623 1.00 51.58 ? 511 NAG B O3 1 HETATM 7957 O O4 . NAG J 2 . ? -24.282 -28.214 -2.699 1.00 51.96 ? 511 NAG B O4 1 HETATM 7958 O O5 . NAG J 2 . ? -21.015 -26.770 -3.524 1.00 50.27 ? 511 NAG B O5 1 HETATM 7959 O O6 . NAG J 2 . ? -21.256 -29.634 -3.272 1.00 52.33 ? 511 NAG B O6 1 HETATM 7960 O O7 . NAG J 2 . ? -22.814 -23.955 -6.988 1.00 53.32 ? 511 NAG B O7 1 HETATM 7961 ZN ZN . ZN K 3 . ? -11.315 -7.687 -14.726 1.00 45.29 ? 512 ZN B ZN 1 HETATM 7962 N N1 . CFE L 4 . ? -12.160 -4.309 -16.764 1.00 33.95 ? 513 CFE B N1 1 HETATM 7963 C C2 . CFE L 4 . ? -13.330 -4.293 -17.457 1.00 32.97 ? 513 CFE B C2 1 HETATM 7964 N N3 . CFE L 4 . ? -14.373 -4.510 -16.635 1.00 34.34 ? 513 CFE B N3 1 HETATM 7965 N N4 . CFE L 4 . ? -14.581 -4.900 -14.265 1.00 34.73 ? 513 CFE B N4 1 HETATM 7966 C C5 . CFE L 4 . ? -14.219 -4.748 -13.054 1.00 34.42 ? 513 CFE B C5 1 HETATM 7967 N N6 . CFE L 4 . ? -13.129 -4.303 -12.553 1.00 34.72 ? 513 CFE B N6 1 HETATM 7968 C C7 . CFE L 4 . ? -11.904 -3.776 -13.175 1.00 33.59 ? 513 CFE B C7 1 HETATM 7969 C C8 . CFE L 4 . ? -11.409 -4.623 -14.336 1.00 33.17 ? 513 CFE B C8 1 HETATM 7970 O O8 . CFE L 4 . ? -11.179 -5.967 -13.896 1.00 33.13 ? 513 CFE B O8 1 HETATM 7971 C C9 . CFE L 4 . ? -12.384 -4.538 -15.449 1.00 33.63 ? 513 CFE B C9 1 HETATM 7972 C C10 . CFE L 4 . ? -13.853 -4.635 -15.407 1.00 34.79 ? 513 CFE B C10 1 HETATM 7973 C C1S . CFE L 4 . ? -15.801 -4.546 -17.023 1.00 33.95 ? 513 CFE B C1S 1 HETATM 7974 C C2S . CFE L 4 . ? -16.276 -3.113 -17.197 1.00 33.34 ? 513 CFE B C2S 1 HETATM 7975 O O2S . CFE L 4 . ? -17.401 -2.894 -16.355 1.00 32.05 ? 513 CFE B O2S 1 HETATM 7976 C C3S . CFE L 4 . ? -16.676 -2.988 -18.652 1.00 34.34 ? 513 CFE B C3S 1 HETATM 7977 O O3S . CFE L 4 . ? -17.927 -2.312 -18.779 1.00 35.77 ? 513 CFE B O3S 1 HETATM 7978 C C4S . CFE L 4 . ? -16.807 -4.422 -19.131 1.00 34.85 ? 513 CFE B C4S 1 HETATM 7979 O O4S . CFE L 4 . ? -15.970 -5.212 -18.278 1.00 34.71 ? 513 CFE B O4S 1 HETATM 7980 C C5S . CFE L 4 . ? -16.391 -4.578 -20.582 1.00 35.32 ? 513 CFE B C5S 1 HETATM 7981 O O5S . CFE L 4 . ? -16.799 -5.878 -21.017 1.00 35.69 ? 513 CFE B O5S 1 HETATM 7982 O O . HOH M 5 . ? 23.410 39.424 23.365 1.00 16.87 ? 514 HOH A O 1 HETATM 7983 O O . HOH M 5 . ? -1.395 3.415 -1.445 1.00 5.60 ? 515 HOH A O 1 HETATM 7984 O O . HOH M 5 . ? 36.041 11.053 20.244 1.00 29.76 ? 516 HOH A O 1 HETATM 7985 O O . HOH M 5 . ? -0.408 1.412 21.809 1.00 11.00 ? 517 HOH A O 1 HETATM 7986 O O . HOH M 5 . ? 18.631 5.165 37.956 1.00 36.68 ? 518 HOH A O 1 HETATM 7987 O O . HOH M 5 . ? -5.930 19.865 6.904 1.00 22.57 ? 519 HOH A O 1 HETATM 7988 O O . HOH M 5 . ? -23.768 12.023 25.473 1.00 35.89 ? 520 HOH A O 1 HETATM 7989 O O . HOH M 5 . ? 10.841 5.916 21.985 1.00 20.27 ? 521 HOH A O 1 HETATM 7990 O O . HOH M 5 . ? 5.281 -5.310 4.650 1.00 28.30 ? 522 HOH A O 1 HETATM 7991 O O . HOH M 5 . ? -2.115 13.528 37.413 1.00 32.70 ? 523 HOH A O 1 HETATM 7992 O O . HOH M 5 . ? 21.598 9.243 9.499 1.00 12.02 ? 524 HOH A O 1 HETATM 7993 O O . HOH M 5 . ? 16.817 -5.693 24.115 1.00 18.39 ? 525 HOH A O 1 HETATM 7994 O O . HOH M 5 . ? 15.446 -10.809 2.608 1.00 23.70 ? 526 HOH A O 1 HETATM 7995 O O . HOH M 5 . ? -3.542 6.884 29.543 1.00 22.65 ? 527 HOH A O 1 HETATM 7996 O O . HOH M 5 . ? -12.165 -4.369 9.366 1.00 27.53 ? 528 HOH A O 1 HETATM 7997 O O . HOH M 5 . ? 14.175 3.254 10.395 1.00 20.47 ? 529 HOH A O 1 HETATM 7998 O O . HOH M 5 . ? 7.947 6.815 8.535 1.00 23.01 ? 530 HOH A O 1 HETATM 7999 O O . HOH M 5 . ? 22.137 18.136 37.405 1.00 40.10 ? 531 HOH A O 1 HETATM 8000 O O . HOH M 5 . ? 12.396 24.835 4.606 1.00 42.39 ? 532 HOH A O 1 HETATM 8001 O O . HOH M 5 . ? 4.729 -0.141 10.580 1.00 24.52 ? 533 HOH A O 1 HETATM 8002 O O . HOH M 5 . ? -11.363 -6.613 18.392 1.00 19.88 ? 534 HOH A O 1 HETATM 8003 O O . HOH M 5 . ? 23.594 -9.969 13.097 1.00 34.61 ? 535 HOH A O 1 HETATM 8004 O O . HOH M 5 . ? 2.984 3.585 22.173 1.00 24.08 ? 536 HOH A O 1 HETATM 8005 O O . HOH M 5 . ? 8.565 18.014 45.773 1.00 57.60 ? 537 HOH A O 1 HETATM 8006 O O . HOH M 5 . ? 1.256 -12.265 12.729 1.00 29.97 ? 538 HOH A O 1 HETATM 8007 O O . HOH M 5 . ? 3.257 8.759 13.454 1.00 28.66 ? 539 HOH A O 1 HETATM 8008 O O . HOH M 5 . ? 4.235 -5.279 7.953 1.00 26.10 ? 540 HOH A O 1 HETATM 8009 O O . HOH M 5 . ? 16.465 10.357 18.145 1.00 19.62 ? 541 HOH A O 1 HETATM 8010 O O . HOH M 5 . ? 9.579 19.632 18.571 1.00 32.83 ? 542 HOH A O 1 HETATM 8011 O O . HOH M 5 . ? -5.398 3.765 -2.614 1.00 25.76 ? 543 HOH A O 1 HETATM 8012 O O . HOH M 5 . ? 16.503 4.220 11.297 1.00 24.92 ? 544 HOH A O 1 HETATM 8013 O O . HOH M 5 . ? 14.154 37.368 21.460 1.00 28.06 ? 545 HOH A O 1 HETATM 8014 O O . HOH M 5 . ? 8.709 -3.189 2.544 1.00 18.55 ? 546 HOH A O 1 HETATM 8015 O O . HOH M 5 . ? 26.782 27.276 12.473 1.00 63.22 ? 547 HOH A O 1 HETATM 8016 O O . HOH M 5 . ? -0.634 3.625 23.284 1.00 15.94 ? 548 HOH A O 1 HETATM 8017 O O . HOH M 5 . ? 15.432 -1.599 29.295 1.00 22.69 ? 549 HOH A O 1 HETATM 8018 O O . HOH M 5 . ? 19.199 21.199 34.515 1.00 32.48 ? 550 HOH A O 1 HETATM 8019 O O . HOH M 5 . ? -10.152 9.078 31.427 1.00 26.99 ? 551 HOH A O 1 HETATM 8020 O O . HOH M 5 . ? 19.848 15.769 22.002 1.00 23.59 ? 552 HOH A O 1 HETATM 8021 O O . HOH M 5 . ? 22.807 30.363 30.833 1.00 30.59 ? 553 HOH A O 1 HETATM 8022 O O . HOH M 5 . ? 16.314 6.854 -0.309 1.00 27.91 ? 554 HOH A O 1 HETATM 8023 O O . HOH M 5 . ? 20.495 -5.147 -0.647 1.00 28.02 ? 555 HOH A O 1 HETATM 8024 O O . HOH M 5 . ? 13.982 5.268 7.245 1.00 31.90 ? 556 HOH A O 1 HETATM 8025 O O . HOH M 5 . ? 21.740 -18.990 24.934 1.00 57.04 ? 557 HOH A O 1 HETATM 8026 O O . HOH M 5 . ? 13.978 0.588 31.802 1.00 45.43 ? 558 HOH A O 1 HETATM 8027 O O . HOH M 5 . ? 24.084 18.003 27.743 1.00 24.04 ? 559 HOH A O 1 HETATM 8028 O O . HOH M 5 . ? 34.760 2.910 11.822 1.00 42.53 ? 560 HOH A O 1 HETATM 8029 O O . HOH M 5 . ? 11.684 38.908 19.742 1.00 47.02 ? 561 HOH A O 1 HETATM 8030 O O . HOH M 5 . ? 22.204 8.184 5.018 1.00 26.93 ? 562 HOH A O 1 HETATM 8031 O O . HOH M 5 . ? 21.501 -5.728 8.903 1.00 30.20 ? 563 HOH A O 1 HETATM 8032 O O . HOH M 5 . ? -1.043 11.617 17.031 1.00 36.11 ? 564 HOH A O 1 HETATM 8033 O O . HOH M 5 . ? 20.943 20.628 37.071 1.00 25.55 ? 565 HOH A O 1 HETATM 8034 O O . HOH M 5 . ? -8.963 -11.200 11.368 1.00 18.12 ? 566 HOH A O 1 HETATM 8035 O O . HOH M 5 . ? 4.636 13.698 2.412 1.00 24.16 ? 567 HOH A O 1 HETATM 8036 O O . HOH M 5 . ? -22.328 -15.415 7.953 1.00 36.43 ? 568 HOH A O 1 HETATM 8037 O O . HOH M 5 . ? 2.109 10.272 1.263 1.00 18.66 ? 569 HOH A O 1 HETATM 8038 O O . HOH M 5 . ? 23.079 -5.429 5.431 1.00 38.55 ? 570 HOH A O 1 HETATM 8039 O O . HOH M 5 . ? 21.225 7.426 7.482 1.00 36.30 ? 571 HOH A O 1 HETATM 8040 O O . HOH M 5 . ? 9.612 8.306 -3.470 1.00 28.97 ? 572 HOH A O 1 HETATM 8041 O O . HOH M 5 . ? 23.967 10.966 19.667 1.00 30.19 ? 573 HOH A O 1 HETATM 8042 O O . HOH M 5 . ? 9.302 -4.603 26.958 1.00 31.35 ? 574 HOH A O 1 HETATM 8043 O O . HOH M 5 . ? 2.210 11.718 14.484 1.00 34.22 ? 575 HOH A O 1 HETATM 8044 O O . HOH M 5 . ? 25.697 30.438 23.918 1.00 28.02 ? 576 HOH A O 1 HETATM 8045 O O . HOH M 5 . ? 30.233 8.688 19.443 1.00 30.40 ? 577 HOH A O 1 HETATM 8046 O O . HOH M 5 . ? 6.357 -19.188 9.246 1.00 42.01 ? 578 HOH A O 1 HETATM 8047 O O . HOH M 5 . ? 18.166 14.693 23.619 1.00 31.70 ? 579 HOH A O 1 HETATM 8048 O O . HOH M 5 . ? 2.676 16.681 20.888 1.00 22.65 ? 580 HOH A O 1 HETATM 8049 O O . HOH M 5 . ? 20.132 -0.165 6.301 1.00 26.40 ? 581 HOH A O 1 HETATM 8050 O O . HOH M 5 . ? 16.346 38.303 20.580 1.00 47.29 ? 582 HOH A O 1 HETATM 8051 O O . HOH M 5 . ? 20.808 16.650 25.297 1.00 32.40 ? 583 HOH A O 1 HETATM 8052 O O . HOH M 5 . ? 25.915 26.459 21.279 1.00 56.28 ? 584 HOH A O 1 HETATM 8053 O O . HOH M 5 . ? 10.982 9.385 34.980 1.00 31.95 ? 585 HOH A O 1 HETATM 8054 O O . HOH M 5 . ? 28.484 10.028 17.984 1.00 38.29 ? 586 HOH A O 1 HETATM 8055 O O . HOH M 5 . ? 16.456 33.919 27.815 1.00 47.54 ? 587 HOH A O 1 HETATM 8056 O O . HOH M 5 . ? 13.913 26.552 4.319 1.00 38.55 ? 588 HOH A O 1 HETATM 8057 O O . HOH M 5 . ? 34.873 12.231 22.070 1.00 29.18 ? 589 HOH A O 1 HETATM 8058 O O . HOH M 5 . ? 35.336 10.709 17.866 1.00 48.10 ? 590 HOH A O 1 HETATM 8059 O O . HOH M 5 . ? 11.797 3.022 1.271 1.00 23.89 ? 591 HOH A O 1 HETATM 8060 O O . HOH M 5 . ? 6.874 23.768 5.328 1.00 41.11 ? 592 HOH A O 1 HETATM 8061 O O . HOH M 5 . ? 9.573 -10.973 0.880 1.00 18.39 ? 593 HOH A O 1 HETATM 8062 O O . HOH M 5 . ? -17.190 -9.666 25.077 1.00 26.05 ? 594 HOH A O 1 HETATM 8063 O O . HOH M 5 . ? -19.406 -8.657 26.360 1.00 31.27 ? 595 HOH A O 1 HETATM 8064 O O . HOH M 5 . ? 14.045 4.365 4.649 1.00 20.25 ? 596 HOH A O 1 HETATM 8065 O O . HOH M 5 . ? 18.090 0.867 13.785 1.00 27.78 ? 597 HOH A O 1 HETATM 8066 O O . HOH M 5 . ? 5.418 12.701 -4.838 1.00 29.70 ? 598 HOH A O 1 HETATM 8067 O O . HOH M 5 . ? 10.518 23.343 5.660 1.00 31.01 ? 599 HOH A O 1 HETATM 8068 O O . HOH M 5 . ? 1.868 32.882 15.155 1.00 37.85 ? 600 HOH A O 1 HETATM 8069 O O . HOH M 5 . ? -4.349 10.941 6.736 1.00 25.68 ? 601 HOH A O 1 HETATM 8070 O O . HOH M 5 . ? 11.231 6.247 35.612 1.00 32.87 ? 602 HOH A O 1 HETATM 8071 O O . HOH M 5 . ? 12.603 5.994 2.989 1.00 37.75 ? 603 HOH A O 1 HETATM 8072 O O . HOH M 5 . ? 20.880 27.343 32.971 1.00 40.31 ? 604 HOH A O 1 HETATM 8073 O O . HOH M 5 . ? 37.638 13.431 16.213 1.00 42.15 ? 605 HOH A O 1 HETATM 8074 O O . HOH M 5 . ? 10.824 7.672 3.947 1.00 33.83 ? 606 HOH A O 1 HETATM 8075 O O . HOH M 5 . ? -18.683 -13.167 13.455 1.00 44.90 ? 607 HOH A O 1 HETATM 8076 O O . HOH M 5 . ? -19.041 6.675 -4.085 1.00 37.41 ? 608 HOH A O 1 HETATM 8077 O O . HOH M 5 . ? 35.652 14.993 16.637 1.00 48.08 ? 609 HOH A O 1 HETATM 8078 O O . HOH M 5 . ? 25.440 15.841 25.804 1.00 35.40 ? 610 HOH A O 1 HETATM 8079 O O . HOH M 5 . ? 9.058 8.359 -6.920 1.00 26.56 ? 611 HOH A O 1 HETATM 8080 O O . HOH M 5 . ? 10.150 10.148 -8.285 1.00 29.63 ? 612 HOH A O 1 HETATM 8081 O O . HOH M 5 . ? 35.294 16.153 18.961 1.00 47.24 ? 613 HOH A O 1 HETATM 8082 O O . HOH M 5 . ? 19.758 15.304 14.961 1.00 32.17 ? 614 HOH A O 1 HETATM 8083 O O . HOH M 5 . ? -13.191 4.515 37.619 1.00 39.60 ? 615 HOH A O 1 HETATM 8084 O O . HOH M 5 . ? 17.769 -0.972 11.007 1.00 23.91 ? 616 HOH A O 1 HETATM 8085 O O . HOH M 5 . ? -0.467 10.596 1.097 1.00 27.73 ? 617 HOH A O 1 HETATM 8086 O O . HOH M 5 . ? 4.732 14.075 -0.297 1.00 39.96 ? 618 HOH A O 1 HETATM 8087 O O . HOH M 5 . ? -16.419 -5.399 15.052 1.00 24.09 ? 619 HOH A O 1 HETATM 8088 O O . HOH M 5 . ? -12.379 -7.253 8.428 1.00 24.60 ? 620 HOH A O 1 HETATM 8089 O O . HOH M 5 . ? -17.653 20.562 10.206 1.00 40.21 ? 621 HOH A O 1 HETATM 8090 O O . HOH M 5 . ? -12.251 -22.838 10.178 1.00 51.88 ? 622 HOH A O 1 HETATM 8091 O O . HOH M 5 . ? 13.682 -8.967 7.867 1.00 17.56 ? 623 HOH A O 1 HETATM 8092 O O . HOH M 5 . ? -3.097 -3.082 0.441 1.00 31.71 ? 624 HOH A O 1 HETATM 8093 O O . HOH M 5 . ? -20.143 -15.396 12.308 1.00 34.48 ? 625 HOH A O 1 HETATM 8094 O O . HOH M 5 . ? 33.858 13.079 17.253 1.00 32.06 ? 626 HOH A O 1 HETATM 8095 O O . HOH M 5 . ? -16.756 -8.044 14.513 1.00 26.18 ? 627 HOH A O 1 HETATM 8096 O O . HOH M 5 . ? 8.398 33.439 28.250 1.00 35.89 ? 628 HOH A O 1 HETATM 8097 O O . HOH M 5 . ? 0.607 -6.812 4.369 1.00 42.09 ? 629 HOH A O 1 HETATM 8098 O O . HOH M 5 . ? 26.122 -7.042 22.301 1.00 63.25 ? 630 HOH A O 1 HETATM 8099 O O . HOH M 5 . ? -13.002 -7.870 16.641 1.00 36.96 ? 631 HOH A O 1 HETATM 8100 O O . HOH M 5 . ? 27.318 11.779 36.162 1.00 79.93 ? 632 HOH A O 1 HETATM 8101 O O . HOH M 5 . ? 1.346 25.060 15.888 1.00 52.50 ? 633 HOH A O 1 HETATM 8102 O O . HOH M 5 . ? 19.729 26.130 15.228 1.00 42.18 ? 634 HOH A O 1 HETATM 8103 O O . HOH M 5 . ? 1.794 10.201 -3.810 1.00 34.84 ? 635 HOH A O 1 HETATM 8104 O O . HOH M 5 . ? -10.852 6.097 -2.895 1.00 34.33 ? 636 HOH A O 1 HETATM 8105 O O . HOH M 5 . ? -13.331 16.233 17.517 1.00 47.57 ? 637 HOH A O 1 HETATM 8106 O O . HOH M 5 . ? 19.465 10.261 8.248 1.00 27.08 ? 638 HOH A O 1 HETATM 8107 O O . HOH M 5 . ? 1.558 20.027 15.762 1.00 41.25 ? 639 HOH A O 1 HETATM 8108 O O . HOH N 5 . ? -22.632 5.924 -45.727 1.00 10.23 ? 514 HOH B O 1 HETATM 8109 O O . HOH N 5 . ? 1.401 3.057 -2.029 1.00 7.24 ? 515 HOH B O 1 HETATM 8110 O O . HOH N 5 . ? -10.833 -13.674 -18.196 1.00 17.00 ? 516 HOH B O 1 HETATM 8111 O O . HOH N 5 . ? 3.495 -19.549 -23.549 1.00 28.44 ? 517 HOH B O 1 HETATM 8112 O O . HOH N 5 . ? -20.680 -9.877 -28.688 1.00 26.57 ? 518 HOH B O 1 HETATM 8113 O O . HOH N 5 . ? -13.850 5.847 -42.606 1.00 26.37 ? 519 HOH B O 1 HETATM 8114 O O . HOH N 5 . ? 1.172 -6.414 -19.725 1.00 28.29 ? 520 HOH B O 1 HETATM 8115 O O . HOH N 5 . ? -15.642 -8.632 7.294 1.00 23.50 ? 521 HOH B O 1 HETATM 8116 O O . HOH N 5 . ? -11.692 0.750 -3.117 1.00 20.61 ? 522 HOH B O 1 HETATM 8117 O O . HOH N 5 . ? -21.677 -1.819 -13.542 1.00 19.35 ? 523 HOH B O 1 HETATM 8118 O O . HOH N 5 . ? -8.551 -4.017 1.016 1.00 10.52 ? 524 HOH B O 1 HETATM 8119 O O . HOH N 5 . ? -21.395 -10.592 -0.744 1.00 24.36 ? 525 HOH B O 1 HETATM 8120 O O . HOH N 5 . ? -25.719 -22.186 -8.547 1.00 35.42 ? 526 HOH B O 1 HETATM 8121 O O . HOH N 5 . ? -10.011 -20.927 7.458 1.00 24.62 ? 527 HOH B O 1 HETATM 8122 O O . HOH N 5 . ? -28.874 -8.996 -42.277 1.00 36.37 ? 528 HOH B O 1 HETATM 8123 O O . HOH N 5 . ? -26.344 -11.702 -40.848 1.00 26.31 ? 529 HOH B O 1 HETATM 8124 O O . HOH N 5 . ? -7.901 -2.646 -10.682 1.00 20.64 ? 530 HOH B O 1 HETATM 8125 O O . HOH N 5 . ? 0.596 -16.248 -17.101 1.00 19.57 ? 531 HOH B O 1 HETATM 8126 O O . HOH N 5 . ? -22.582 -18.759 -36.999 1.00 29.67 ? 532 HOH B O 1 HETATM 8127 O O . HOH N 5 . ? -20.959 -1.404 -10.486 1.00 26.82 ? 533 HOH B O 1 HETATM 8128 O O . HOH N 5 . ? 9.757 -18.808 12.073 1.00 28.82 ? 534 HOH B O 1 HETATM 8129 O O . HOH N 5 . ? 0.367 -16.347 -14.475 1.00 22.70 ? 535 HOH B O 1 HETATM 8130 O O . HOH N 5 . ? -19.635 -7.717 -25.862 1.00 36.99 ? 536 HOH B O 1 HETATM 8131 O O . HOH N 5 . ? -23.787 -11.145 -31.159 1.00 27.65 ? 537 HOH B O 1 HETATM 8132 O O . HOH N 5 . ? -4.609 -9.211 -0.790 1.00 25.17 ? 538 HOH B O 1 HETATM 8133 O O . HOH N 5 . ? -19.024 4.189 -10.893 1.00 32.75 ? 539 HOH B O 1 HETATM 8134 O O . HOH N 5 . ? -5.242 -6.828 1.143 1.00 24.80 ? 540 HOH B O 1 HETATM 8135 O O . HOH N 5 . ? -22.096 0.775 -16.518 1.00 43.67 ? 541 HOH B O 1 HETATM 8136 O O . HOH N 5 . ? 0.714 5.500 -9.222 1.00 23.85 ? 542 HOH B O 1 HETATM 8137 O O . HOH N 5 . ? -31.041 -3.586 -14.106 1.00 32.11 ? 543 HOH B O 1 HETATM 8138 O O . HOH N 5 . ? -14.086 -1.132 -6.395 1.00 23.29 ? 544 HOH B O 1 HETATM 8139 O O . HOH N 5 . ? 12.182 -9.897 -2.259 1.00 54.58 ? 545 HOH B O 1 HETATM 8140 O O . HOH N 5 . ? -19.419 1.522 -20.259 1.00 36.42 ? 546 HOH B O 1 HETATM 8141 O O . HOH N 5 . ? -33.360 -7.723 -19.979 1.00 40.55 ? 547 HOH B O 1 HETATM 8142 O O . HOH N 5 . ? 13.484 -4.338 -23.663 1.00 51.35 ? 548 HOH B O 1 HETATM 8143 O O . HOH N 5 . ? -17.625 -9.462 -5.941 1.00 19.97 ? 549 HOH B O 1 HETATM 8144 O O . HOH N 5 . ? -0.619 -2.300 0.774 1.00 30.97 ? 550 HOH B O 1 HETATM 8145 O O . HOH N 5 . ? -14.222 -24.550 -13.697 1.00 37.02 ? 551 HOH B O 1 HETATM 8146 O O . HOH N 5 . ? 11.340 -18.306 -5.760 1.00 27.81 ? 552 HOH B O 1 HETATM 8147 O O . HOH N 5 . ? -14.772 -3.289 -42.648 1.00 23.42 ? 553 HOH B O 1 HETATM 8148 O O . HOH N 5 . ? -36.980 -11.086 -16.686 1.00 30.98 ? 554 HOH B O 1 HETATM 8149 O O . HOH N 5 . ? -14.401 -6.394 -8.906 1.00 30.48 ? 555 HOH B O 1 HETATM 8150 O O . HOH N 5 . ? -23.556 -23.190 -9.905 1.00 30.59 ? 556 HOH B O 1 HETATM 8151 O O . HOH N 5 . ? -13.914 -11.802 2.355 1.00 30.00 ? 557 HOH B O 1 HETATM 8152 O O . HOH N 5 . ? -5.573 -7.508 -9.174 1.00 32.31 ? 558 HOH B O 1 HETATM 8153 O O . HOH N 5 . ? -3.230 -5.152 -15.012 1.00 26.01 ? 559 HOH B O 1 HETATM 8154 O O . HOH N 5 . ? -4.628 -8.519 -6.270 1.00 23.40 ? 560 HOH B O 1 HETATM 8155 O O . HOH N 5 . ? 5.454 -18.722 -35.368 1.00 45.68 ? 561 HOH B O 1 HETATM 8156 O O . HOH N 5 . ? -16.672 -6.324 -10.475 1.00 20.62 ? 562 HOH B O 1 HETATM 8157 O O . HOH N 5 . ? 6.114 6.205 -20.379 1.00 28.44 ? 563 HOH B O 1 HETATM 8158 O O . HOH N 5 . ? -26.135 14.554 -29.880 1.00 43.07 ? 564 HOH B O 1 HETATM 8159 O O . HOH N 5 . ? -3.800 0.899 -26.722 1.00 35.26 ? 565 HOH B O 1 HETATM 8160 O O . HOH N 5 . ? -9.185 13.604 -24.839 1.00 40.37 ? 566 HOH B O 1 HETATM 8161 O O . HOH N 5 . ? 27.574 -11.098 -22.398 1.00 33.82 ? 567 HOH B O 1 HETATM 8162 O O . HOH N 5 . ? -2.075 -4.416 -18.282 1.00 26.40 ? 568 HOH B O 1 HETATM 8163 O O . HOH N 5 . ? -9.805 8.085 -4.333 1.00 35.48 ? 569 HOH B O 1 HETATM 8164 O O . HOH N 5 . ? 9.059 -15.920 2.020 1.00 25.80 ? 570 HOH B O 1 HETATM 8165 O O . HOH N 5 . ? 22.558 -15.541 7.455 1.00 35.92 ? 571 HOH B O 1 HETATM 8166 O O . HOH N 5 . ? 20.112 -19.262 4.669 1.00 37.25 ? 572 HOH B O 1 HETATM 8167 O O . HOH N 5 . ? 16.197 -15.228 -5.058 1.00 27.73 ? 573 HOH B O 1 HETATM 8168 O O . HOH N 5 . ? -16.876 -22.431 -10.194 1.00 23.24 ? 574 HOH B O 1 HETATM 8169 O O . HOH N 5 . ? -6.785 -5.354 10.130 1.00 18.23 ? 575 HOH B O 1 HETATM 8170 O O . HOH N 5 . ? 24.086 -7.123 -10.634 1.00 27.54 ? 576 HOH B O 1 HETATM 8171 O O . HOH N 5 . ? 3.858 -2.645 2.063 1.00 25.06 ? 577 HOH B O 1 HETATM 8172 O O . HOH N 5 . ? -19.426 -0.210 -13.419 1.00 23.68 ? 578 HOH B O 1 HETATM 8173 O O . HOH N 5 . ? -19.429 3.608 -30.394 1.00 31.28 ? 579 HOH B O 1 HETATM 8174 O O . HOH N 5 . ? -21.832 -9.452 3.903 1.00 35.41 ? 580 HOH B O 1 HETATM 8175 O O . HOH N 5 . ? -35.973 -9.022 -20.972 1.00 41.54 ? 581 HOH B O 1 HETATM 8176 O O . HOH N 5 . ? -10.319 -33.389 -16.946 1.00 39.54 ? 582 HOH B O 1 HETATM 8177 O O . HOH N 5 . ? -13.994 8.195 -24.223 1.00 30.21 ? 583 HOH B O 1 HETATM 8178 O O . HOH N 5 . ? -15.189 -27.492 -17.904 1.00 35.74 ? 584 HOH B O 1 HETATM 8179 O O . HOH N 5 . ? -25.553 -10.803 -28.504 1.00 27.58 ? 585 HOH B O 1 HETATM 8180 O O . HOH N 5 . ? -10.044 -23.272 6.503 1.00 29.17 ? 586 HOH B O 1 HETATM 8181 O O . HOH N 5 . ? -34.083 -5.380 -21.182 1.00 37.75 ? 587 HOH B O 1 HETATM 8182 O O . HOH N 5 . ? -33.776 -9.605 -22.932 1.00 48.02 ? 588 HOH B O 1 HETATM 8183 O O . HOH N 5 . ? -35.284 -4.891 -23.681 1.00 38.48 ? 589 HOH B O 1 HETATM 8184 O O . HOH N 5 . ? -3.023 -15.641 -16.470 1.00 26.57 ? 590 HOH B O 1 HETATM 8185 O O . HOH N 5 . ? 10.170 -19.630 -26.046 1.00 38.13 ? 591 HOH B O 1 HETATM 8186 O O . HOH N 5 . ? -11.684 8.071 -43.270 1.00 43.96 ? 592 HOH B O 1 HETATM 8187 O O . HOH N 5 . ? 22.110 1.347 -4.927 1.00 32.08 ? 593 HOH B O 1 HETATM 8188 O O . HOH N 5 . ? 12.806 -18.469 -3.517 1.00 32.42 ? 594 HOH B O 1 HETATM 8189 O O . HOH N 5 . ? -34.740 -7.528 -9.601 1.00 42.50 ? 595 HOH B O 1 HETATM 8190 O O . HOH N 5 . ? 11.764 -22.490 11.884 1.00 46.48 ? 596 HOH B O 1 HETATM 8191 O O . HOH N 5 . ? -20.700 -2.435 4.113 1.00 30.59 ? 597 HOH B O 1 HETATM 8192 O O . HOH N 5 . ? -9.913 14.900 -26.944 1.00 47.32 ? 598 HOH B O 1 HETATM 8193 O O . HOH N 5 . ? 2.842 10.102 -12.607 1.00 35.78 ? 599 HOH B O 1 HETATM 8194 O O . HOH N 5 . ? 13.129 6.185 -23.885 1.00 58.86 ? 600 HOH B O 1 HETATM 8195 O O . HOH N 5 . ? -26.701 -15.425 3.630 1.00 50.74 ? 601 HOH B O 1 HETATM 8196 O O . HOH N 5 . ? -16.391 -8.077 -19.449 1.00 26.93 ? 602 HOH B O 1 HETATM 8197 O O . HOH N 5 . ? 6.135 -25.683 -28.741 1.00 27.06 ? 603 HOH B O 1 HETATM 8198 O O . HOH N 5 . ? 3.460 -4.804 0.205 1.00 43.23 ? 604 HOH B O 1 HETATM 8199 O O . HOH N 5 . ? -11.634 14.571 -28.744 1.00 41.00 ? 605 HOH B O 1 HETATM 8200 O O . HOH N 5 . ? -19.878 -5.138 -3.557 1.00 28.31 ? 606 HOH B O 1 HETATM 8201 O O . HOH N 5 . ? -23.708 -8.901 -20.892 1.00 34.89 ? 607 HOH B O 1 HETATM 8202 O O . HOH N 5 . ? -12.333 -29.296 -25.805 1.00 30.71 ? 608 HOH B O 1 HETATM 8203 O O . HOH N 5 . ? -22.959 -5.934 -42.996 1.00 32.66 ? 609 HOH B O 1 HETATM 8204 O O . HOH N 5 . ? -6.715 9.634 -21.895 1.00 44.07 ? 610 HOH B O 1 HETATM 8205 O O . HOH N 5 . ? 11.851 4.207 -2.512 1.00 47.91 ? 611 HOH B O 1 HETATM 8206 O O . HOH N 5 . ? -24.070 -16.083 0.067 1.00 31.10 ? 612 HOH B O 1 HETATM 8207 O O . HOH N 5 . ? 4.608 8.778 -11.277 1.00 31.22 ? 613 HOH B O 1 HETATM 8208 O O . HOH N 5 . ? 5.674 4.660 -1.618 1.00 24.89 ? 614 HOH B O 1 HETATM 8209 O O . HOH N 5 . ? 0.331 16.566 -8.517 1.00 50.31 ? 615 HOH B O 1 HETATM 8210 O O . HOH N 5 . ? -1.072 -17.799 1.712 1.00 29.46 ? 616 HOH B O 1 HETATM 8211 O O . HOH N 5 . ? -14.034 -2.435 -8.789 1.00 43.13 ? 617 HOH B O 1 HETATM 8212 O O . HOH N 5 . ? -9.710 10.599 -3.043 1.00 41.97 ? 618 HOH B O 1 HETATM 8213 O O . HOH N 5 . ? -10.907 1.265 -8.241 1.00 29.33 ? 619 HOH B O 1 HETATM 8214 O O . HOH N 5 . ? -36.986 -4.408 -21.679 1.00 49.36 ? 620 HOH B O 1 HETATM 8215 O O . HOH N 5 . ? -22.056 0.809 -9.652 1.00 32.17 ? 621 HOH B O 1 HETATM 8216 O O . HOH N 5 . ? -0.116 -11.620 5.629 1.00 45.46 ? 622 HOH B O 1 HETATM 8217 O O . HOH N 5 . ? -14.771 -24.654 -1.278 1.00 52.14 ? 623 HOH B O 1 HETATM 8218 O O . HOH N 5 . ? -25.921 13.064 -23.292 1.00 59.18 ? 624 HOH B O 1 HETATM 8219 O O . HOH N 5 . ? -2.292 5.102 -8.892 1.00 22.30 ? 625 HOH B O 1 HETATM 8220 O O . HOH N 5 . ? 17.832 -24.535 -22.447 1.00 54.06 ? 626 HOH B O 1 HETATM 8221 O O . HOH N 5 . ? -12.634 -21.979 -29.768 1.00 58.10 ? 627 HOH B O 1 HETATM 8222 O O . HOH N 5 . ? -15.891 7.105 -43.095 1.00 37.57 ? 628 HOH B O 1 HETATM 8223 O O . HOH N 5 . ? -0.552 -8.545 2.186 1.00 58.83 ? 629 HOH B O 1 HETATM 8224 O O . HOH N 5 . ? 8.720 -26.038 -28.567 1.00 44.36 ? 630 HOH B O 1 HETATM 8225 O O . HOH N 5 . ? -4.630 -32.159 -26.286 1.00 34.06 ? 631 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 1 ? ? ? A . n A 1 2 GLY 2 2 ? ? ? A . n A 1 3 SER 3 3 3 SER SER A . n A 1 4 ILE 4 4 4 ILE ILE A . n A 1 5 ASP 5 5 5 ASP ASP A . n A 1 6 GLU 6 6 6 GLU GLU A . n A 1 7 THR 7 7 7 THR THR A . n A 1 8 ARG 8 8 8 ARG ARG A . n A 1 9 ALA 9 9 9 ALA ALA A . n A 1 10 HIS 10 10 10 HIS HIS A . n A 1 11 LEU 11 11 11 LEU LEU A . n A 1 12 LEU 12 12 12 LEU LEU A . n A 1 13 LEU 13 13 13 LEU LEU A . n A 1 14 LYS 14 14 14 LYS LYS A . n A 1 15 GLU 15 15 15 GLU GLU A . n A 1 16 LYS 16 16 16 LYS LYS A . n A 1 17 MET 17 17 17 MET MET A . n A 1 18 MET 18 18 18 MET MET A . n A 1 19 ARG 19 19 19 ARG ARG A . n A 1 20 LEU 20 20 20 LEU LEU A . n A 1 21 GLY 21 21 21 GLY GLY A . n A 1 22 GLY 22 22 22 GLY GLY A . n A 1 23 ARG 23 23 23 ARG ARG A . n A 1 24 LEU 24 24 24 LEU LEU A . n A 1 25 VAL 25 25 25 VAL VAL A . n A 1 26 LEU 26 26 26 LEU LEU A . n A 1 27 ASN 27 27 27 ASN ASN A . n A 1 28 THR 28 28 28 THR THR A . n A 1 29 LYS 29 29 29 LYS LYS A . n A 1 30 GLU 30 30 30 GLU GLU A . n A 1 31 GLU 31 31 31 GLU GLU A . n A 1 32 LEU 32 32 32 LEU LEU A . n A 1 33 ALA 33 33 33 ALA ALA A . n A 1 34 ASN 34 34 34 ASN ASN A . n A 1 35 GLU 35 35 35 GLU GLU A . n A 1 36 ARG 36 36 36 ARG ARG A . n A 1 37 LEU 37 37 37 LEU LEU A . n A 1 38 MET 38 38 38 MET MET A . n A 1 39 THR 39 39 39 THR THR A . n A 1 40 LEU 40 40 40 LEU LEU A . n A 1 41 LYS 41 41 41 LYS LYS A . n A 1 42 ILE 42 42 42 ILE ILE A . n A 1 43 ALA 43 43 43 ALA ALA A . n A 1 44 GLU 44 44 44 GLU GLU A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LYS 46 46 46 LYS LYS A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 ALA 48 48 48 ALA ALA A . n A 1 49 MET 49 49 49 MET MET A . n A 1 50 ARG 50 50 50 ARG ARG A . n A 1 51 THR 51 51 51 THR THR A . n A 1 52 LEU 52 52 52 LEU LEU A . n A 1 53 ILE 53 53 53 ILE ILE A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 PRO 55 55 55 PRO PRO A . n A 1 56 PRO 56 56 56 PRO PRO A . n A 1 57 SER 57 57 57 SER SER A . n A 1 58 MET 58 58 58 MET MET A . n A 1 59 HIS 59 59 59 HIS HIS A . n A 1 60 PHE 60 60 60 PHE PHE A . n A 1 61 PHE 61 61 61 PHE PHE A . n A 1 62 GLN 62 62 62 GLN GLN A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 LYS 64 64 64 LYS LYS A . n A 1 65 HIS 65 65 65 HIS HIS A . n A 1 66 LEU 66 66 66 LEU LEU A . n A 1 67 ILE 67 67 67 ILE ILE A . n A 1 68 GLU 68 68 68 GLU GLU A . n A 1 69 ARG 69 69 69 ARG ARG A . n A 1 70 SER 70 70 70 SER SER A . n A 1 71 GLN 71 71 71 GLN GLN A . n A 1 72 VAL 72 72 72 VAL VAL A . n A 1 73 PHE 73 73 73 PHE PHE A . n A 1 74 ASN 74 74 74 ASN ASN A . n A 1 75 ILE 75 75 75 ILE ILE A . n A 1 76 LEU 76 76 76 LEU LEU A . n A 1 77 ARG 77 77 77 ARG ARG A . n A 1 78 MET 78 78 78 MET MET A . n A 1 79 MET 79 79 79 MET MET A . n A 1 80 PRO 80 80 80 PRO PRO A . n A 1 81 LYS 81 81 81 LYS LYS A . n A 1 82 GLY 82 82 82 GLY GLY A . n A 1 83 ALA 83 83 83 ALA ALA A . n A 1 84 ALA 84 84 84 ALA ALA A . n A 1 85 LEU 85 85 85 LEU LEU A . n A 1 86 HIS 86 86 86 HIS HIS A . n A 1 87 LEU 87 87 87 LEU LEU A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 ASP 89 89 89 ASP ASP A . n A 1 90 ILE 90 90 90 ILE ILE A . n A 1 91 GLY 91 91 91 GLY GLY A . n A 1 92 ILE 92 92 92 ILE ILE A . n A 1 93 VAL 93 93 93 VAL VAL A . n A 1 94 THR 94 94 94 THR THR A . n A 1 95 MET 95 95 95 MET MET A . n A 1 96 ASP 96 96 96 ASP ASP A . n A 1 97 TRP 97 97 97 TRP TRP A . n A 1 98 LEU 98 98 98 LEU LEU A . n A 1 99 VAL 99 99 99 VAL VAL A . n A 1 100 ARG 100 100 100 ARG ARG A . n A 1 101 ASN 101 101 101 ASN ASN A . n A 1 102 VAL 102 102 102 VAL VAL A . n A 1 103 THR 103 103 103 THR THR A . n A 1 104 TYR 104 104 104 TYR TYR A . n A 1 105 ARG 105 105 105 ARG ARG A . n A 1 106 PRO 106 106 106 PRO PRO A . n A 1 107 HIS 107 107 107 HIS HIS A . n A 1 108 CYS 108 108 108 CYS CYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 CYS 111 111 111 CYS CYS A . n A 1 112 PHE 112 112 112 PHE PHE A . n A 1 113 THR 113 113 113 THR THR A . n A 1 114 PRO 114 114 114 PRO PRO A . n A 1 115 ARG 115 115 115 ARG ARG A . n A 1 116 GLY 116 116 116 GLY GLY A . n A 1 117 ILE 117 117 117 ILE ILE A . n A 1 118 MET 118 118 118 MET MET A . n A 1 119 GLN 119 119 119 GLN GLN A . n A 1 120 PHE 120 120 120 PHE PHE A . n A 1 121 ARG 121 121 121 ARG ARG A . n A 1 122 PHE 122 122 122 PHE PHE A . n A 1 123 ALA 123 123 123 ALA ALA A . n A 1 124 HIS 124 124 124 HIS HIS A . n A 1 125 PRO 125 125 125 PRO PRO A . n A 1 126 THR 126 126 126 THR THR A . n A 1 127 PRO 127 127 127 PRO PRO A . n A 1 128 ARG 128 128 128 ARG ARG A . n A 1 129 PRO 129 129 129 PRO PRO A . n A 1 130 SER 130 130 130 SER SER A . n A 1 131 GLU 131 131 131 GLU GLU A . n A 1 132 LYS 132 132 132 LYS LYS A . n A 1 133 CYS 133 133 133 CYS CYS A . n A 1 134 SER 134 134 134 SER SER A . n A 1 135 LYS 135 135 135 LYS LYS A . n A 1 136 TRP 136 136 136 TRP TRP A . n A 1 137 ILE 137 137 137 ILE ILE A . n A 1 138 LEU 138 138 138 LEU LEU A . n A 1 139 LEU 139 139 139 LEU LEU A . n A 1 140 GLU 140 140 140 GLU GLU A . n A 1 141 ASP 141 141 141 ASP ASP A . n A 1 142 TYR 142 142 142 TYR TYR A . n A 1 143 ARG 143 143 143 ARG ARG A . n A 1 144 LYS 144 144 144 LYS LYS A . n A 1 145 ARG 145 145 145 ARG ARG A . n A 1 146 VAL 146 146 146 VAL VAL A . n A 1 147 GLN 147 147 147 GLN GLN A . n A 1 148 ASN 148 148 148 ASN ASN A . n A 1 149 VAL 149 149 149 VAL VAL A . n A 1 150 THR 150 150 150 THR THR A . n A 1 151 GLU 151 151 151 GLU GLU A . n A 1 152 PHE 152 152 152 PHE PHE A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 ASP 154 154 154 ASP ASP A . n A 1 155 SER 155 155 155 SER SER A . n A 1 156 LEU 156 156 156 LEU LEU A . n A 1 157 LEU 157 157 157 LEU LEU A . n A 1 158 ARG 158 158 158 ARG ARG A . n A 1 159 ASN 159 159 159 ASN ASN A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 THR 161 161 161 THR THR A . n A 1 162 LEU 162 162 162 LEU LEU A . n A 1 163 VAL 163 163 163 VAL VAL A . n A 1 164 THR 164 164 164 THR THR A . n A 1 165 GLN 165 165 165 GLN GLN A . n A 1 166 HIS 166 166 166 HIS HIS A . n A 1 167 PRO 167 167 167 PRO PRO A . n A 1 168 GLU 168 168 168 GLU GLU A . n A 1 169 VAL 169 169 169 VAL VAL A . n A 1 170 ILE 170 170 170 ILE ILE A . n A 1 171 TYR 171 171 171 TYR TYR A . n A 1 172 THR 172 172 172 THR THR A . n A 1 173 ASN 173 173 173 ASN ASN A . n A 1 174 GLN 174 174 174 GLN GLN A . n A 1 175 ASN 175 175 175 ASN ASN A . n A 1 176 VAL 176 176 176 VAL VAL A . n A 1 177 VAL 177 177 177 VAL VAL A . n A 1 178 TRP 178 178 178 TRP TRP A . n A 1 179 SER 179 179 179 SER SER A . n A 1 180 LYS 180 180 180 LYS LYS A . n A 1 181 PHE 181 181 181 PHE PHE A . n A 1 182 GLU 182 182 182 GLU GLU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 ILE 184 184 184 ILE ILE A . n A 1 185 PHE 185 185 185 PHE PHE A . n A 1 186 PHE 186 186 186 PHE PHE A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 ILE 188 188 188 ILE ILE A . n A 1 189 SER 189 189 189 SER SER A . n A 1 190 GLY 190 190 190 GLY GLY A . n A 1 191 LEU 191 191 191 LEU LEU A . n A 1 192 ILE 192 192 192 ILE ILE A . n A 1 193 HIS 193 193 193 HIS HIS A . n A 1 194 TYR 194 194 194 TYR TYR A . n A 1 195 ALA 195 195 195 ALA ALA A . n A 1 196 PRO 196 196 196 PRO PRO A . n A 1 197 VAL 197 197 197 VAL VAL A . n A 1 198 PHE 198 198 198 PHE PHE A . n A 1 199 ARG 199 199 199 ARG ARG A . n A 1 200 ASP 200 200 200 ASP ASP A . n A 1 201 TYR 201 201 201 TYR TYR A . n A 1 202 VAL 202 202 202 VAL VAL A . n A 1 203 PHE 203 203 203 PHE PHE A . n A 1 204 ARG 204 204 204 ARG ARG A . n A 1 205 SER 205 205 205 SER SER A . n A 1 206 MET 206 206 206 MET MET A . n A 1 207 GLN 207 207 207 GLN GLN A . n A 1 208 GLU 208 208 208 GLU GLU A . n A 1 209 PHE 209 209 209 PHE PHE A . n A 1 210 TYR 210 210 210 TYR TYR A . n A 1 211 GLU 211 211 211 GLU GLU A . n A 1 212 ASP 212 212 212 ASP ASP A . n A 1 213 ASN 213 213 213 ASN ASN A . n A 1 214 VAL 214 214 214 VAL VAL A . n A 1 215 LEU 215 215 215 LEU LEU A . n A 1 216 TYR 216 216 216 TYR TYR A . n A 1 217 MET 217 217 217 MET MET A . n A 1 218 GLU 218 218 218 GLU GLU A . n A 1 219 ILE 219 219 219 ILE ILE A . n A 1 220 ARG 220 220 220 ARG ARG A . n A 1 221 ALA 221 221 221 ALA ALA A . n A 1 222 ARG 222 222 222 ARG ARG A . n A 1 223 LEU 223 223 223 LEU LEU A . n A 1 224 LEU 224 224 224 LEU LEU A . n A 1 225 PRO 225 225 225 PRO PRO A . n A 1 226 VAL 226 226 226 VAL VAL A . n A 1 227 TYR 227 227 227 TYR TYR A . n A 1 228 GLU 228 228 228 GLU GLU A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 SER 230 230 230 SER SER A . n A 1 231 GLY 231 231 231 GLY GLY A . n A 1 232 GLU 232 232 232 GLU GLU A . n A 1 233 HIS 233 233 233 HIS HIS A . n A 1 234 HIS 234 234 234 HIS HIS A . n A 1 235 ASP 235 235 235 ASP ASP A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 GLU 237 237 237 GLU GLU A . n A 1 238 TRP 238 238 238 TRP TRP A . n A 1 239 SER 239 239 239 SER SER A . n A 1 240 VAL 240 240 240 VAL VAL A . n A 1 241 LYS 241 241 241 LYS LYS A . n A 1 242 THR 242 242 242 THR THR A . n A 1 243 TYR 243 243 243 TYR TYR A . n A 1 244 GLN 244 244 244 GLN GLN A . n A 1 245 GLU 245 245 245 GLU GLU A . n A 1 246 VAL 246 246 246 VAL VAL A . n A 1 247 ALA 247 247 247 ALA ALA A . n A 1 248 GLN 248 248 248 GLN GLN A . n A 1 249 LYS 249 249 249 LYS LYS A . n A 1 250 PHE 250 250 250 PHE PHE A . n A 1 251 VAL 251 251 251 VAL VAL A . n A 1 252 GLU 252 252 252 GLU GLU A . n A 1 253 THR 253 253 253 THR THR A . n A 1 254 HIS 254 254 254 HIS HIS A . n A 1 255 PRO 255 255 255 PRO PRO A . n A 1 256 GLU 256 256 256 GLU GLU A . n A 1 257 PHE 257 257 257 PHE PHE A . n A 1 258 ILE 258 258 258 ILE ILE A . n A 1 259 GLY 259 259 259 GLY GLY A . n A 1 260 ILE 260 260 260 ILE ILE A . n A 1 261 LYS 261 261 261 LYS LYS A . n A 1 262 ILE 262 262 262 ILE ILE A . n A 1 263 ILE 263 263 263 ILE ILE A . n A 1 264 TYR 264 264 264 TYR TYR A . n A 1 265 SER 265 265 265 SER SER A . n A 1 266 ASP 266 266 266 ASP ASP A . n A 1 267 HIS 267 267 267 HIS HIS A . n A 1 268 ARG 268 268 268 ARG ARG A . n A 1 269 SER 269 269 269 SER SER A . n A 1 270 LYS 270 270 270 LYS LYS A . n A 1 271 ASP 271 271 271 ASP ASP A . n A 1 272 VAL 272 272 272 VAL VAL A . n A 1 273 ALA 273 273 273 ALA ALA A . n A 1 274 VAL 274 274 274 VAL VAL A . n A 1 275 ILE 275 275 275 ILE ILE A . n A 1 276 ALA 276 276 276 ALA ALA A . n A 1 277 GLU 277 277 277 GLU GLU A . n A 1 278 SER 278 278 278 SER SER A . n A 1 279 ILE 279 279 279 ILE ILE A . n A 1 280 ARG 280 280 280 ARG ARG A . n A 1 281 MET 281 281 281 MET MET A . n A 1 282 ALA 282 282 282 ALA ALA A . n A 1 283 MET 283 283 283 MET MET A . n A 1 284 GLY 284 284 284 GLY GLY A . n A 1 285 LEU 285 285 285 LEU LEU A . n A 1 286 ARG 286 286 286 ARG ARG A . n A 1 287 ILE 287 287 287 ILE ILE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 PHE 289 289 289 PHE PHE A . n A 1 290 PRO 290 290 290 PRO PRO A . n A 1 291 THR 291 291 291 THR THR A . n A 1 292 VAL 292 292 292 VAL VAL A . n A 1 293 VAL 293 293 293 VAL VAL A . n A 1 294 ALA 294 294 294 ALA ALA A . n A 1 295 GLY 295 295 295 GLY GLY A . n A 1 296 PHE 296 296 296 PHE PHE A . n A 1 297 ASP 297 297 297 ASP ASP A . n A 1 298 LEU 298 298 298 LEU LEU A . n A 1 299 VAL 299 299 299 VAL VAL A . n A 1 300 GLY 300 300 300 GLY GLY A . n A 1 301 HIS 301 301 301 HIS HIS A . n A 1 302 GLU 302 302 302 GLU GLU A . n A 1 303 ASP 303 303 303 ASP ASP A . n A 1 304 THR 304 304 304 THR THR A . n A 1 305 GLY 305 305 305 GLY GLY A . n A 1 306 HIS 306 306 306 HIS HIS A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 LEU 308 308 308 LEU LEU A . n A 1 309 HIS 309 309 309 HIS HIS A . n A 1 310 ASP 310 310 310 ASP ASP A . n A 1 311 TYR 311 311 311 TYR TYR A . n A 1 312 LYS 312 312 312 LYS LYS A . n A 1 313 GLU 313 313 313 GLU GLU A . n A 1 314 ALA 314 314 314 ALA ALA A . n A 1 315 LEU 315 315 315 LEU LEU A . n A 1 316 MET 316 316 316 MET MET A . n A 1 317 ILE 317 317 317 ILE ILE A . n A 1 318 PRO 318 318 318 PRO PRO A . n A 1 319 ALA 319 319 319 ALA ALA A . n A 1 320 LYS 320 320 320 LYS LYS A . n A 1 321 ASP 321 321 321 ASP ASP A . n A 1 322 GLY 322 322 322 GLY GLY A . n A 1 323 VAL 323 323 323 VAL VAL A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LEU 325 325 325 LEU LEU A . n A 1 326 PRO 326 326 326 PRO PRO A . n A 1 327 TYR 327 327 327 TYR TYR A . n A 1 328 PHE 328 328 328 PHE PHE A . n A 1 329 PHE 329 329 329 PHE PHE A . n A 1 330 HIS 330 330 330 HIS HIS A . n A 1 331 ALA 331 331 331 ALA ALA A . n A 1 332 GLY 332 332 332 GLY GLY A . n A 1 333 GLU 333 333 333 GLU GLU A . n A 1 334 THR 334 334 334 THR THR A . n A 1 335 ASP 335 335 335 ASP ASP A . n A 1 336 TRP 336 336 336 TRP TRP A . n A 1 337 GLN 337 337 337 GLN GLN A . n A 1 338 GLY 338 338 338 GLY GLY A . n A 1 339 THR 339 339 339 THR THR A . n A 1 340 SER 340 340 340 SER SER A . n A 1 341 ILE 341 341 341 ILE ILE A . n A 1 342 ASP 342 342 342 ASP ASP A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 ASN 344 344 344 ASN ASN A . n A 1 345 ILE 345 345 345 ILE ILE A . n A 1 346 LEU 346 346 346 LEU LEU A . n A 1 347 ASP 347 347 347 ASP ASP A . n A 1 348 ALA 348 348 348 ALA ALA A . n A 1 349 LEU 349 349 349 LEU LEU A . n A 1 350 MET 350 350 350 MET MET A . n A 1 351 LEU 351 351 351 LEU LEU A . n A 1 352 ASN 352 352 352 ASN ASN A . n A 1 353 THR 353 353 353 THR THR A . n A 1 354 THR 354 354 354 THR THR A . n A 1 355 ARG 355 355 355 ARG ARG A . n A 1 356 ILE 356 356 356 ILE ILE A . n A 1 357 GLY 357 357 357 GLY GLY A . n A 1 358 HIS 358 358 358 HIS HIS A . n A 1 359 GLY 359 359 359 GLY GLY A . n A 1 360 PHE 360 360 360 PHE PHE A . n A 1 361 ALA 361 361 361 ALA ALA A . n A 1 362 LEU 362 362 362 LEU LEU A . n A 1 363 SER 363 363 363 SER SER A . n A 1 364 LYS 364 364 364 LYS LYS A . n A 1 365 HIS 365 365 365 HIS HIS A . n A 1 366 PRO 366 366 366 PRO PRO A . n A 1 367 ALA 367 367 367 ALA ALA A . n A 1 368 VAL 368 368 368 VAL VAL A . n A 1 369 ARG 369 369 369 ARG ARG A . n A 1 370 THR 370 370 370 THR THR A . n A 1 371 TYR 371 371 371 TYR TYR A . n A 1 372 SER 372 372 372 SER SER A . n A 1 373 TRP 373 373 373 TRP TRP A . n A 1 374 LYS 374 374 374 LYS LYS A . n A 1 375 LYS 375 375 375 LYS LYS A . n A 1 376 ASP 376 376 376 ASP ASP A . n A 1 377 ILE 377 377 377 ILE ILE A . n A 1 378 PRO 378 378 378 PRO PRO A . n A 1 379 ILE 379 379 379 ILE ILE A . n A 1 380 GLU 380 380 380 GLU GLU A . n A 1 381 VAL 381 381 381 VAL VAL A . n A 1 382 CYS 382 382 382 CYS CYS A . n A 1 383 PRO 383 383 383 PRO PRO A . n A 1 384 ILE 384 384 384 ILE ILE A . n A 1 385 SER 385 385 385 SER SER A . n A 1 386 ASN 386 386 386 ASN ASN A . n A 1 387 GLN 387 387 387 GLN GLN A . n A 1 388 VAL 388 388 388 VAL VAL A . n A 1 389 LEU 389 389 389 LEU LEU A . n A 1 390 LYS 390 390 390 LYS LYS A . n A 1 391 LEU 391 391 391 LEU LEU A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 SER 393 393 393 SER SER A . n A 1 394 ASP 394 394 394 ASP ASP A . n A 1 395 LEU 395 395 395 LEU LEU A . n A 1 396 ARG 396 396 396 ARG ARG A . n A 1 397 ASN 397 397 397 ASN ASN A . n A 1 398 HIS 398 398 398 HIS HIS A . n A 1 399 PRO 399 399 399 PRO PRO A . n A 1 400 VAL 400 400 400 VAL VAL A . n A 1 401 ALA 401 401 401 ALA ALA A . n A 1 402 THR 402 402 402 THR THR A . n A 1 403 LEU 403 403 403 LEU LEU A . n A 1 404 MET 404 404 404 MET MET A . n A 1 405 ALA 405 405 405 ALA ALA A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 GLY 407 407 407 GLY GLY A . n A 1 408 HIS 408 408 408 HIS HIS A . n A 1 409 PRO 409 409 409 PRO PRO A . n A 1 410 MET 410 410 410 MET MET A . n A 1 411 VAL 411 411 411 VAL VAL A . n A 1 412 ILE 412 412 412 ILE ILE A . n A 1 413 SER 413 413 413 SER SER A . n A 1 414 SER 414 414 414 SER SER A . n A 1 415 ASP 415 415 415 ASP ASP A . n A 1 416 ASP 416 416 416 ASP ASP A . n A 1 417 PRO 417 417 417 PRO PRO A . n A 1 418 ALA 418 418 418 ALA ALA A . n A 1 419 MET 419 419 419 MET MET A . n A 1 420 PHE 420 420 420 PHE PHE A . n A 1 421 GLY 421 421 421 GLY GLY A . n A 1 422 ALA 422 422 422 ALA ALA A . n A 1 423 LYS 423 423 423 LYS LYS A . n A 1 424 GLY 424 424 424 GLY GLY A . n A 1 425 LEU 425 425 425 LEU LEU A . n A 1 426 SER 426 426 426 SER SER A . n A 1 427 TYR 427 427 427 TYR TYR A . n A 1 428 ASP 428 428 428 ASP ASP A . n A 1 429 PHE 429 429 429 PHE PHE A . n A 1 430 TYR 430 430 430 TYR TYR A . n A 1 431 GLU 431 431 431 GLU GLU A . n A 1 432 VAL 432 432 432 VAL VAL A . n A 1 433 PHE 433 433 433 PHE PHE A . n A 1 434 MET 434 434 434 MET MET A . n A 1 435 GLY 435 435 435 GLY GLY A . n A 1 436 ILE 436 436 436 ILE ILE A . n A 1 437 GLY 437 437 437 GLY GLY A . n A 1 438 GLY 438 438 438 GLY GLY A . n A 1 439 MET 439 439 439 MET MET A . n A 1 440 LYS 440 440 440 LYS LYS A . n A 1 441 ALA 441 441 441 ALA ALA A . n A 1 442 ASP 442 442 442 ASP ASP A . n A 1 443 LEU 443 443 443 LEU LEU A . n A 1 444 ARG 444 444 444 ARG ARG A . n A 1 445 THR 445 445 445 THR THR A . n A 1 446 LEU 446 446 446 LEU LEU A . n A 1 447 LYS 447 447 447 LYS LYS A . n A 1 448 GLN 448 448 448 GLN GLN A . n A 1 449 LEU 449 449 449 LEU LEU A . n A 1 450 ALA 450 450 450 ALA ALA A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ASN 452 452 452 ASN ASN A . n A 1 453 SER 453 453 453 SER SER A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 LYS 455 455 455 LYS LYS A . n A 1 456 TYR 456 456 456 TYR TYR A . n A 1 457 SER 457 457 457 SER SER A . n A 1 458 THR 458 458 458 THR THR A . n A 1 459 LEU 459 459 459 LEU LEU A . n A 1 460 LEU 460 460 460 LEU LEU A . n A 1 461 GLU 461 461 461 GLU GLU A . n A 1 462 SER 462 462 462 SER SER A . n A 1 463 GLU 463 463 463 GLU GLU A . n A 1 464 LYS 464 464 464 LYS LYS A . n A 1 465 ASN 465 465 465 ASN ASN A . n A 1 466 THR 466 466 466 THR THR A . n A 1 467 PHE 467 467 467 PHE PHE A . n A 1 468 MET 468 468 468 MET MET A . n A 1 469 GLU 469 469 469 GLU GLU A . n A 1 470 ILE 470 470 470 ILE ILE A . n A 1 471 TRP 471 471 471 TRP TRP A . n A 1 472 LYS 472 472 472 LYS LYS A . n A 1 473 LYS 473 473 473 LYS LYS A . n A 1 474 ARG 474 474 474 ARG ARG A . n A 1 475 TRP 475 475 475 TRP TRP A . n A 1 476 ASP 476 476 476 ASP ASP A . n A 1 477 LYS 477 477 477 LYS LYS A . n A 1 478 PHE 478 478 478 PHE PHE A . n A 1 479 ILE 479 479 479 ILE ILE A . n A 1 480 ALA 480 480 480 ALA ALA A . n A 1 481 ASP 481 481 481 ASP ASP A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 ALA 483 483 483 ALA ALA A . n A 1 484 THR 484 484 484 THR THR A . n A 1 485 LYS 485 485 ? ? ? A . n A 1 486 GLY 486 486 ? ? ? A . n A 1 487 SER 487 487 ? ? ? A . n A 1 488 LEU 488 488 ? ? ? A . n A 1 489 HIS 489 489 ? ? ? A . n A 1 490 HIS 490 490 ? ? ? A . n A 1 491 ILE 491 491 ? ? ? A . n A 1 492 LEU 492 492 ? ? ? A . n A 1 493 ASP 493 493 ? ? ? A . n A 1 494 ALA 494 494 ? ? ? A . n A 1 495 GLN 495 495 ? ? ? A . n A 1 496 LYS 496 496 ? ? ? A . n A 1 497 MET 497 497 ? ? ? A . n A 1 498 VAL 498 498 ? ? ? A . n A 1 499 TRP 499 499 ? ? ? A . n A 1 500 ASN 500 500 ? ? ? A . n A 1 501 HIS 501 501 ? ? ? A . n A 1 502 ARG 502 502 ? ? ? A . n A 1 503 HIS 503 503 ? ? ? A . n A 1 504 HIS 504 504 ? ? ? A . n A 1 505 HIS 505 505 ? ? ? A . n A 1 506 HIS 506 506 ? ? ? A . n A 1 507 HIS 507 507 ? ? ? A . n A 1 508 HIS 508 508 ? ? ? A . n B 1 1 GLY 1 1 ? ? ? B . n B 1 2 GLY 2 2 ? ? ? B . n B 1 3 SER 3 3 3 SER SER B . n B 1 4 ILE 4 4 4 ILE ILE B . n B 1 5 ASP 5 5 5 ASP ASP B . n B 1 6 GLU 6 6 6 GLU GLU B . n B 1 7 THR 7 7 7 THR THR B . n B 1 8 ARG 8 8 8 ARG ARG B . n B 1 9 ALA 9 9 9 ALA ALA B . n B 1 10 HIS 10 10 10 HIS HIS B . n B 1 11 LEU 11 11 11 LEU LEU B . n B 1 12 LEU 12 12 12 LEU LEU B . n B 1 13 LEU 13 13 13 LEU LEU B . n B 1 14 LYS 14 14 14 LYS LYS B . n B 1 15 GLU 15 15 15 GLU GLU B . n B 1 16 LYS 16 16 16 LYS LYS B . n B 1 17 MET 17 17 17 MET MET B . n B 1 18 MET 18 18 18 MET MET B . n B 1 19 ARG 19 19 19 ARG ARG B . n B 1 20 LEU 20 20 20 LEU LEU B . n B 1 21 GLY 21 21 21 GLY GLY B . n B 1 22 GLY 22 22 22 GLY GLY B . n B 1 23 ARG 23 23 23 ARG ARG B . n B 1 24 LEU 24 24 24 LEU LEU B . n B 1 25 VAL 25 25 25 VAL VAL B . n B 1 26 LEU 26 26 26 LEU LEU B . n B 1 27 ASN 27 27 27 ASN ASN B . n B 1 28 THR 28 28 28 THR THR B . n B 1 29 LYS 29 29 29 LYS LYS B . n B 1 30 GLU 30 30 30 GLU GLU B . n B 1 31 GLU 31 31 31 GLU GLU B . n B 1 32 LEU 32 32 32 LEU LEU B . n B 1 33 ALA 33 33 33 ALA ALA B . n B 1 34 ASN 34 34 34 ASN ASN B . n B 1 35 GLU 35 35 35 GLU GLU B . n B 1 36 ARG 36 36 36 ARG ARG B . n B 1 37 LEU 37 37 37 LEU LEU B . n B 1 38 MET 38 38 38 MET MET B . n B 1 39 THR 39 39 39 THR THR B . n B 1 40 LEU 40 40 40 LEU LEU B . n B 1 41 LYS 41 41 41 LYS LYS B . n B 1 42 ILE 42 42 42 ILE ILE B . n B 1 43 ALA 43 43 43 ALA ALA B . n B 1 44 GLU 44 44 44 GLU GLU B . n B 1 45 MET 45 45 45 MET MET B . n B 1 46 LYS 46 46 46 LYS LYS B . n B 1 47 GLU 47 47 47 GLU GLU B . n B 1 48 ALA 48 48 48 ALA ALA B . n B 1 49 MET 49 49 49 MET MET B . n B 1 50 ARG 50 50 50 ARG ARG B . n B 1 51 THR 51 51 51 THR THR B . n B 1 52 LEU 52 52 52 LEU LEU B . n B 1 53 ILE 53 53 53 ILE ILE B . n B 1 54 PHE 54 54 54 PHE PHE B . n B 1 55 PRO 55 55 55 PRO PRO B . n B 1 56 PRO 56 56 56 PRO PRO B . n B 1 57 SER 57 57 57 SER SER B . n B 1 58 MET 58 58 58 MET MET B . n B 1 59 HIS 59 59 59 HIS HIS B . n B 1 60 PHE 60 60 60 PHE PHE B . n B 1 61 PHE 61 61 61 PHE PHE B . n B 1 62 GLN 62 62 62 GLN GLN B . n B 1 63 ALA 63 63 63 ALA ALA B . n B 1 64 LYS 64 64 64 LYS LYS B . n B 1 65 HIS 65 65 65 HIS HIS B . n B 1 66 LEU 66 66 66 LEU LEU B . n B 1 67 ILE 67 67 67 ILE ILE B . n B 1 68 GLU 68 68 68 GLU GLU B . n B 1 69 ARG 69 69 69 ARG ARG B . n B 1 70 SER 70 70 70 SER SER B . n B 1 71 GLN 71 71 71 GLN GLN B . n B 1 72 VAL 72 72 72 VAL VAL B . n B 1 73 PHE 73 73 73 PHE PHE B . n B 1 74 ASN 74 74 74 ASN ASN B . n B 1 75 ILE 75 75 75 ILE ILE B . n B 1 76 LEU 76 76 76 LEU LEU B . n B 1 77 ARG 77 77 77 ARG ARG B . n B 1 78 MET 78 78 78 MET MET B . n B 1 79 MET 79 79 79 MET MET B . n B 1 80 PRO 80 80 80 PRO PRO B . n B 1 81 LYS 81 81 81 LYS LYS B . n B 1 82 GLY 82 82 82 GLY GLY B . n B 1 83 ALA 83 83 83 ALA ALA B . n B 1 84 ALA 84 84 84 ALA ALA B . n B 1 85 LEU 85 85 85 LEU LEU B . n B 1 86 HIS 86 86 86 HIS HIS B . n B 1 87 LEU 87 87 87 LEU LEU B . n B 1 88 HIS 88 88 88 HIS HIS B . n B 1 89 ASP 89 89 89 ASP ASP B . n B 1 90 ILE 90 90 90 ILE ILE B . n B 1 91 GLY 91 91 91 GLY GLY B . n B 1 92 ILE 92 92 92 ILE ILE B . n B 1 93 VAL 93 93 93 VAL VAL B . n B 1 94 THR 94 94 94 THR THR B . n B 1 95 MET 95 95 95 MET MET B . n B 1 96 ASP 96 96 96 ASP ASP B . n B 1 97 TRP 97 97 97 TRP TRP B . n B 1 98 LEU 98 98 98 LEU LEU B . n B 1 99 VAL 99 99 99 VAL VAL B . n B 1 100 ARG 100 100 100 ARG ARG B . n B 1 101 ASN 101 101 101 ASN ASN B . n B 1 102 VAL 102 102 102 VAL VAL B . n B 1 103 THR 103 103 103 THR THR B . n B 1 104 TYR 104 104 104 TYR TYR B . n B 1 105 ARG 105 105 105 ARG ARG B . n B 1 106 PRO 106 106 106 PRO PRO B . n B 1 107 HIS 107 107 107 HIS HIS B . n B 1 108 CYS 108 108 108 CYS CYS B . n B 1 109 HIS 109 109 109 HIS HIS B . n B 1 110 ILE 110 110 110 ILE ILE B . n B 1 111 CYS 111 111 111 CYS CYS B . n B 1 112 PHE 112 112 112 PHE PHE B . n B 1 113 THR 113 113 113 THR THR B . n B 1 114 PRO 114 114 114 PRO PRO B . n B 1 115 ARG 115 115 115 ARG ARG B . n B 1 116 GLY 116 116 116 GLY GLY B . n B 1 117 ILE 117 117 117 ILE ILE B . n B 1 118 MET 118 118 118 MET MET B . n B 1 119 GLN 119 119 119 GLN GLN B . n B 1 120 PHE 120 120 120 PHE PHE B . n B 1 121 ARG 121 121 121 ARG ARG B . n B 1 122 PHE 122 122 122 PHE PHE B . n B 1 123 ALA 123 123 123 ALA ALA B . n B 1 124 HIS 124 124 124 HIS HIS B . n B 1 125 PRO 125 125 125 PRO PRO B . n B 1 126 THR 126 126 126 THR THR B . n B 1 127 PRO 127 127 127 PRO PRO B . n B 1 128 ARG 128 128 128 ARG ARG B . n B 1 129 PRO 129 129 129 PRO PRO B . n B 1 130 SER 130 130 130 SER SER B . n B 1 131 GLU 131 131 131 GLU GLU B . n B 1 132 LYS 132 132 132 LYS LYS B . n B 1 133 CYS 133 133 133 CYS CYS B . n B 1 134 SER 134 134 134 SER SER B . n B 1 135 LYS 135 135 135 LYS LYS B . n B 1 136 TRP 136 136 136 TRP TRP B . n B 1 137 ILE 137 137 137 ILE ILE B . n B 1 138 LEU 138 138 138 LEU LEU B . n B 1 139 LEU 139 139 139 LEU LEU B . n B 1 140 GLU 140 140 140 GLU GLU B . n B 1 141 ASP 141 141 141 ASP ASP B . n B 1 142 TYR 142 142 142 TYR TYR B . n B 1 143 ARG 143 143 143 ARG ARG B . n B 1 144 LYS 144 144 144 LYS LYS B . n B 1 145 ARG 145 145 145 ARG ARG B . n B 1 146 VAL 146 146 146 VAL VAL B . n B 1 147 GLN 147 147 147 GLN GLN B . n B 1 148 ASN 148 148 148 ASN ASN B . n B 1 149 VAL 149 149 149 VAL VAL B . n B 1 150 THR 150 150 150 THR THR B . n B 1 151 GLU 151 151 151 GLU GLU B . n B 1 152 PHE 152 152 152 PHE PHE B . n B 1 153 ASP 153 153 153 ASP ASP B . n B 1 154 ASP 154 154 154 ASP ASP B . n B 1 155 SER 155 155 155 SER SER B . n B 1 156 LEU 156 156 156 LEU LEU B . n B 1 157 LEU 157 157 157 LEU LEU B . n B 1 158 ARG 158 158 158 ARG ARG B . n B 1 159 ASN 159 159 159 ASN ASN B . n B 1 160 PHE 160 160 160 PHE PHE B . n B 1 161 THR 161 161 161 THR THR B . n B 1 162 LEU 162 162 162 LEU LEU B . n B 1 163 VAL 163 163 163 VAL VAL B . n B 1 164 THR 164 164 164 THR THR B . n B 1 165 GLN 165 165 165 GLN GLN B . n B 1 166 HIS 166 166 166 HIS HIS B . n B 1 167 PRO 167 167 167 PRO PRO B . n B 1 168 GLU 168 168 168 GLU GLU B . n B 1 169 VAL 169 169 169 VAL VAL B . n B 1 170 ILE 170 170 170 ILE ILE B . n B 1 171 TYR 171 171 171 TYR TYR B . n B 1 172 THR 172 172 172 THR THR B . n B 1 173 ASN 173 173 173 ASN ASN B . n B 1 174 GLN 174 174 174 GLN GLN B . n B 1 175 ASN 175 175 175 ASN ASN B . n B 1 176 VAL 176 176 176 VAL VAL B . n B 1 177 VAL 177 177 177 VAL VAL B . n B 1 178 TRP 178 178 178 TRP TRP B . n B 1 179 SER 179 179 179 SER SER B . n B 1 180 LYS 180 180 180 LYS LYS B . n B 1 181 PHE 181 181 181 PHE PHE B . n B 1 182 GLU 182 182 182 GLU GLU B . n B 1 183 THR 183 183 183 THR THR B . n B 1 184 ILE 184 184 184 ILE ILE B . n B 1 185 PHE 185 185 185 PHE PHE B . n B 1 186 PHE 186 186 186 PHE PHE B . n B 1 187 THR 187 187 187 THR THR B . n B 1 188 ILE 188 188 188 ILE ILE B . n B 1 189 SER 189 189 189 SER SER B . n B 1 190 GLY 190 190 190 GLY GLY B . n B 1 191 LEU 191 191 191 LEU LEU B . n B 1 192 ILE 192 192 192 ILE ILE B . n B 1 193 HIS 193 193 193 HIS HIS B . n B 1 194 TYR 194 194 194 TYR TYR B . n B 1 195 ALA 195 195 195 ALA ALA B . n B 1 196 PRO 196 196 196 PRO PRO B . n B 1 197 VAL 197 197 197 VAL VAL B . n B 1 198 PHE 198 198 198 PHE PHE B . n B 1 199 ARG 199 199 199 ARG ARG B . n B 1 200 ASP 200 200 200 ASP ASP B . n B 1 201 TYR 201 201 201 TYR TYR B . n B 1 202 VAL 202 202 202 VAL VAL B . n B 1 203 PHE 203 203 203 PHE PHE B . n B 1 204 ARG 204 204 204 ARG ARG B . n B 1 205 SER 205 205 205 SER SER B . n B 1 206 MET 206 206 206 MET MET B . n B 1 207 GLN 207 207 207 GLN GLN B . n B 1 208 GLU 208 208 208 GLU GLU B . n B 1 209 PHE 209 209 209 PHE PHE B . n B 1 210 TYR 210 210 210 TYR TYR B . n B 1 211 GLU 211 211 211 GLU GLU B . n B 1 212 ASP 212 212 212 ASP ASP B . n B 1 213 ASN 213 213 213 ASN ASN B . n B 1 214 VAL 214 214 214 VAL VAL B . n B 1 215 LEU 215 215 215 LEU LEU B . n B 1 216 TYR 216 216 216 TYR TYR B . n B 1 217 MET 217 217 217 MET MET B . n B 1 218 GLU 218 218 218 GLU GLU B . n B 1 219 ILE 219 219 219 ILE ILE B . n B 1 220 ARG 220 220 220 ARG ARG B . n B 1 221 ALA 221 221 221 ALA ALA B . n B 1 222 ARG 222 222 222 ARG ARG B . n B 1 223 LEU 223 223 223 LEU LEU B . n B 1 224 LEU 224 224 224 LEU LEU B . n B 1 225 PRO 225 225 225 PRO PRO B . n B 1 226 VAL 226 226 226 VAL VAL B . n B 1 227 TYR 227 227 227 TYR TYR B . n B 1 228 GLU 228 228 228 GLU GLU B . n B 1 229 LEU 229 229 229 LEU LEU B . n B 1 230 SER 230 230 230 SER SER B . n B 1 231 GLY 231 231 231 GLY GLY B . n B 1 232 GLU 232 232 232 GLU GLU B . n B 1 233 HIS 233 233 233 HIS HIS B . n B 1 234 HIS 234 234 234 HIS HIS B . n B 1 235 ASP 235 235 235 ASP ASP B . n B 1 236 GLU 236 236 236 GLU GLU B . n B 1 237 GLU 237 237 237 GLU GLU B . n B 1 238 TRP 238 238 238 TRP TRP B . n B 1 239 SER 239 239 239 SER SER B . n B 1 240 VAL 240 240 240 VAL VAL B . n B 1 241 LYS 241 241 241 LYS LYS B . n B 1 242 THR 242 242 242 THR THR B . n B 1 243 TYR 243 243 243 TYR TYR B . n B 1 244 GLN 244 244 244 GLN GLN B . n B 1 245 GLU 245 245 245 GLU GLU B . n B 1 246 VAL 246 246 246 VAL VAL B . n B 1 247 ALA 247 247 247 ALA ALA B . n B 1 248 GLN 248 248 248 GLN GLN B . n B 1 249 LYS 249 249 249 LYS LYS B . n B 1 250 PHE 250 250 250 PHE PHE B . n B 1 251 VAL 251 251 251 VAL VAL B . n B 1 252 GLU 252 252 252 GLU GLU B . n B 1 253 THR 253 253 253 THR THR B . n B 1 254 HIS 254 254 254 HIS HIS B . n B 1 255 PRO 255 255 255 PRO PRO B . n B 1 256 GLU 256 256 256 GLU GLU B . n B 1 257 PHE 257 257 257 PHE PHE B . n B 1 258 ILE 258 258 258 ILE ILE B . n B 1 259 GLY 259 259 259 GLY GLY B . n B 1 260 ILE 260 260 260 ILE ILE B . n B 1 261 LYS 261 261 261 LYS LYS B . n B 1 262 ILE 262 262 262 ILE ILE B . n B 1 263 ILE 263 263 263 ILE ILE B . n B 1 264 TYR 264 264 264 TYR TYR B . n B 1 265 SER 265 265 265 SER SER B . n B 1 266 ASP 266 266 266 ASP ASP B . n B 1 267 HIS 267 267 267 HIS HIS B . n B 1 268 ARG 268 268 268 ARG ARG B . n B 1 269 SER 269 269 269 SER SER B . n B 1 270 LYS 270 270 270 LYS LYS B . n B 1 271 ASP 271 271 271 ASP ASP B . n B 1 272 VAL 272 272 272 VAL VAL B . n B 1 273 ALA 273 273 273 ALA ALA B . n B 1 274 VAL 274 274 274 VAL VAL B . n B 1 275 ILE 275 275 275 ILE ILE B . n B 1 276 ALA 276 276 276 ALA ALA B . n B 1 277 GLU 277 277 277 GLU GLU B . n B 1 278 SER 278 278 278 SER SER B . n B 1 279 ILE 279 279 279 ILE ILE B . n B 1 280 ARG 280 280 280 ARG ARG B . n B 1 281 MET 281 281 281 MET MET B . n B 1 282 ALA 282 282 282 ALA ALA B . n B 1 283 MET 283 283 283 MET MET B . n B 1 284 GLY 284 284 284 GLY GLY B . n B 1 285 LEU 285 285 285 LEU LEU B . n B 1 286 ARG 286 286 286 ARG ARG B . n B 1 287 ILE 287 287 287 ILE ILE B . n B 1 288 LYS 288 288 288 LYS LYS B . n B 1 289 PHE 289 289 289 PHE PHE B . n B 1 290 PRO 290 290 290 PRO PRO B . n B 1 291 THR 291 291 291 THR THR B . n B 1 292 VAL 292 292 292 VAL VAL B . n B 1 293 VAL 293 293 293 VAL VAL B . n B 1 294 ALA 294 294 294 ALA ALA B . n B 1 295 GLY 295 295 295 GLY GLY B . n B 1 296 PHE 296 296 296 PHE PHE B . n B 1 297 ASP 297 297 297 ASP ASP B . n B 1 298 LEU 298 298 298 LEU LEU B . n B 1 299 VAL 299 299 299 VAL VAL B . n B 1 300 GLY 300 300 300 GLY GLY B . n B 1 301 HIS 301 301 301 HIS HIS B . n B 1 302 GLU 302 302 302 GLU GLU B . n B 1 303 ASP 303 303 303 ASP ASP B . n B 1 304 THR 304 304 304 THR THR B . n B 1 305 GLY 305 305 305 GLY GLY B . n B 1 306 HIS 306 306 306 HIS HIS B . n B 1 307 SER 307 307 307 SER SER B . n B 1 308 LEU 308 308 308 LEU LEU B . n B 1 309 HIS 309 309 309 HIS HIS B . n B 1 310 ASP 310 310 310 ASP ASP B . n B 1 311 TYR 311 311 311 TYR TYR B . n B 1 312 LYS 312 312 312 LYS LYS B . n B 1 313 GLU 313 313 313 GLU GLU B . n B 1 314 ALA 314 314 314 ALA ALA B . n B 1 315 LEU 315 315 315 LEU LEU B . n B 1 316 MET 316 316 316 MET MET B . n B 1 317 ILE 317 317 317 ILE ILE B . n B 1 318 PRO 318 318 318 PRO PRO B . n B 1 319 ALA 319 319 319 ALA ALA B . n B 1 320 LYS 320 320 320 LYS LYS B . n B 1 321 ASP 321 321 321 ASP ASP B . n B 1 322 GLY 322 322 322 GLY GLY B . n B 1 323 VAL 323 323 323 VAL VAL B . n B 1 324 LYS 324 324 324 LYS LYS B . n B 1 325 LEU 325 325 325 LEU LEU B . n B 1 326 PRO 326 326 326 PRO PRO B . n B 1 327 TYR 327 327 327 TYR TYR B . n B 1 328 PHE 328 328 328 PHE PHE B . n B 1 329 PHE 329 329 329 PHE PHE B . n B 1 330 HIS 330 330 330 HIS HIS B . n B 1 331 ALA 331 331 331 ALA ALA B . n B 1 332 GLY 332 332 332 GLY GLY B . n B 1 333 GLU 333 333 333 GLU GLU B . n B 1 334 THR 334 334 334 THR THR B . n B 1 335 ASP 335 335 335 ASP ASP B . n B 1 336 TRP 336 336 336 TRP TRP B . n B 1 337 GLN 337 337 337 GLN GLN B . n B 1 338 GLY 338 338 338 GLY GLY B . n B 1 339 THR 339 339 339 THR THR B . n B 1 340 SER 340 340 340 SER SER B . n B 1 341 ILE 341 341 341 ILE ILE B . n B 1 342 ASP 342 342 342 ASP ASP B . n B 1 343 ARG 343 343 343 ARG ARG B . n B 1 344 ASN 344 344 344 ASN ASN B . n B 1 345 ILE 345 345 345 ILE ILE B . n B 1 346 LEU 346 346 346 LEU LEU B . n B 1 347 ASP 347 347 347 ASP ASP B . n B 1 348 ALA 348 348 348 ALA ALA B . n B 1 349 LEU 349 349 349 LEU LEU B . n B 1 350 MET 350 350 350 MET MET B . n B 1 351 LEU 351 351 351 LEU LEU B . n B 1 352 ASN 352 352 352 ASN ASN B . n B 1 353 THR 353 353 353 THR THR B . n B 1 354 THR 354 354 354 THR THR B . n B 1 355 ARG 355 355 355 ARG ARG B . n B 1 356 ILE 356 356 356 ILE ILE B . n B 1 357 GLY 357 357 357 GLY GLY B . n B 1 358 HIS 358 358 358 HIS HIS B . n B 1 359 GLY 359 359 359 GLY GLY B . n B 1 360 PHE 360 360 360 PHE PHE B . n B 1 361 ALA 361 361 361 ALA ALA B . n B 1 362 LEU 362 362 362 LEU LEU B . n B 1 363 SER 363 363 363 SER SER B . n B 1 364 LYS 364 364 364 LYS LYS B . n B 1 365 HIS 365 365 365 HIS HIS B . n B 1 366 PRO 366 366 366 PRO PRO B . n B 1 367 ALA 367 367 367 ALA ALA B . n B 1 368 VAL 368 368 368 VAL VAL B . n B 1 369 ARG 369 369 369 ARG ARG B . n B 1 370 THR 370 370 370 THR THR B . n B 1 371 TYR 371 371 371 TYR TYR B . n B 1 372 SER 372 372 372 SER SER B . n B 1 373 TRP 373 373 373 TRP TRP B . n B 1 374 LYS 374 374 374 LYS LYS B . n B 1 375 LYS 375 375 375 LYS LYS B . n B 1 376 ASP 376 376 376 ASP ASP B . n B 1 377 ILE 377 377 377 ILE ILE B . n B 1 378 PRO 378 378 378 PRO PRO B . n B 1 379 ILE 379 379 379 ILE ILE B . n B 1 380 GLU 380 380 380 GLU GLU B . n B 1 381 VAL 381 381 381 VAL VAL B . n B 1 382 CYS 382 382 382 CYS CYS B . n B 1 383 PRO 383 383 383 PRO PRO B . n B 1 384 ILE 384 384 384 ILE ILE B . n B 1 385 SER 385 385 385 SER SER B . n B 1 386 ASN 386 386 386 ASN ASN B . n B 1 387 GLN 387 387 387 GLN GLN B . n B 1 388 VAL 388 388 388 VAL VAL B . n B 1 389 LEU 389 389 389 LEU LEU B . n B 1 390 LYS 390 390 390 LYS LYS B . n B 1 391 LEU 391 391 391 LEU LEU B . n B 1 392 VAL 392 392 392 VAL VAL B . n B 1 393 SER 393 393 393 SER SER B . n B 1 394 ASP 394 394 394 ASP ASP B . n B 1 395 LEU 395 395 395 LEU LEU B . n B 1 396 ARG 396 396 396 ARG ARG B . n B 1 397 ASN 397 397 397 ASN ASN B . n B 1 398 HIS 398 398 398 HIS HIS B . n B 1 399 PRO 399 399 399 PRO PRO B . n B 1 400 VAL 400 400 400 VAL VAL B . n B 1 401 ALA 401 401 401 ALA ALA B . n B 1 402 THR 402 402 402 THR THR B . n B 1 403 LEU 403 403 403 LEU LEU B . n B 1 404 MET 404 404 404 MET MET B . n B 1 405 ALA 405 405 405 ALA ALA B . n B 1 406 THR 406 406 406 THR THR B . n B 1 407 GLY 407 407 407 GLY GLY B . n B 1 408 HIS 408 408 408 HIS HIS B . n B 1 409 PRO 409 409 409 PRO PRO B . n B 1 410 MET 410 410 410 MET MET B . n B 1 411 VAL 411 411 411 VAL VAL B . n B 1 412 ILE 412 412 412 ILE ILE B . n B 1 413 SER 413 413 413 SER SER B . n B 1 414 SER 414 414 414 SER SER B . n B 1 415 ASP 415 415 415 ASP ASP B . n B 1 416 ASP 416 416 416 ASP ASP B . n B 1 417 PRO 417 417 417 PRO PRO B . n B 1 418 ALA 418 418 418 ALA ALA B . n B 1 419 MET 419 419 419 MET MET B . n B 1 420 PHE 420 420 420 PHE PHE B . n B 1 421 GLY 421 421 421 GLY GLY B . n B 1 422 ALA 422 422 422 ALA ALA B . n B 1 423 LYS 423 423 423 LYS LYS B . n B 1 424 GLY 424 424 424 GLY GLY B . n B 1 425 LEU 425 425 425 LEU LEU B . n B 1 426 SER 426 426 426 SER SER B . n B 1 427 TYR 427 427 427 TYR TYR B . n B 1 428 ASP 428 428 428 ASP ASP B . n B 1 429 PHE 429 429 429 PHE PHE B . n B 1 430 TYR 430 430 430 TYR TYR B . n B 1 431 GLU 431 431 431 GLU GLU B . n B 1 432 VAL 432 432 432 VAL VAL B . n B 1 433 PHE 433 433 433 PHE PHE B . n B 1 434 MET 434 434 434 MET MET B . n B 1 435 GLY 435 435 435 GLY GLY B . n B 1 436 ILE 436 436 436 ILE ILE B . n B 1 437 GLY 437 437 437 GLY GLY B . n B 1 438 GLY 438 438 438 GLY GLY B . n B 1 439 MET 439 439 439 MET MET B . n B 1 440 LYS 440 440 440 LYS LYS B . n B 1 441 ALA 441 441 441 ALA ALA B . n B 1 442 ASP 442 442 442 ASP ASP B . n B 1 443 LEU 443 443 443 LEU LEU B . n B 1 444 ARG 444 444 444 ARG ARG B . n B 1 445 THR 445 445 445 THR THR B . n B 1 446 LEU 446 446 446 LEU LEU B . n B 1 447 LYS 447 447 447 LYS LYS B . n B 1 448 GLN 448 448 448 GLN GLN B . n B 1 449 LEU 449 449 449 LEU LEU B . n B 1 450 ALA 450 450 450 ALA ALA B . n B 1 451 MET 451 451 451 MET MET B . n B 1 452 ASN 452 452 452 ASN ASN B . n B 1 453 SER 453 453 453 SER SER B . n B 1 454 ILE 454 454 454 ILE ILE B . n B 1 455 LYS 455 455 455 LYS LYS B . n B 1 456 TYR 456 456 456 TYR TYR B . n B 1 457 SER 457 457 457 SER SER B . n B 1 458 THR 458 458 458 THR THR B . n B 1 459 LEU 459 459 459 LEU LEU B . n B 1 460 LEU 460 460 460 LEU LEU B . n B 1 461 GLU 461 461 461 GLU GLU B . n B 1 462 SER 462 462 462 SER SER B . n B 1 463 GLU 463 463 463 GLU GLU B . n B 1 464 LYS 464 464 464 LYS LYS B . n B 1 465 ASN 465 465 465 ASN ASN B . n B 1 466 THR 466 466 466 THR THR B . n B 1 467 PHE 467 467 467 PHE PHE B . n B 1 468 MET 468 468 468 MET MET B . n B 1 469 GLU 469 469 469 GLU GLU B . n B 1 470 ILE 470 470 470 ILE ILE B . n B 1 471 TRP 471 471 471 TRP TRP B . n B 1 472 LYS 472 472 472 LYS LYS B . n B 1 473 LYS 473 473 473 LYS LYS B . n B 1 474 ARG 474 474 474 ARG ARG B . n B 1 475 TRP 475 475 475 TRP TRP B . n B 1 476 ASP 476 476 476 ASP ASP B . n B 1 477 LYS 477 477 477 LYS LYS B . n B 1 478 PHE 478 478 478 PHE PHE B . n B 1 479 ILE 479 479 479 ILE ILE B . n B 1 480 ALA 480 480 480 ALA ALA B . n B 1 481 ASP 481 481 481 ASP ASP B . n B 1 482 VAL 482 482 482 VAL VAL B . n B 1 483 ALA 483 483 483 ALA ALA B . n B 1 484 THR 484 484 484 THR THR B . n B 1 485 LYS 485 485 ? ? ? B . n B 1 486 GLY 486 486 ? ? ? B . n B 1 487 SER 487 487 ? ? ? B . n B 1 488 LEU 488 488 ? ? ? B . n B 1 489 HIS 489 489 ? ? ? B . n B 1 490 HIS 490 490 ? ? ? B . n B 1 491 ILE 491 491 ? ? ? B . n B 1 492 LEU 492 492 ? ? ? B . n B 1 493 ASP 493 493 ? ? ? B . n B 1 494 ALA 494 494 ? ? ? B . n B 1 495 GLN 495 495 ? ? ? B . n B 1 496 LYS 496 496 ? ? ? B . n B 1 497 MET 497 497 ? ? ? B . n B 1 498 VAL 498 498 ? ? ? B . n B 1 499 TRP 499 499 ? ? ? B . n B 1 500 ASN 500 500 ? ? ? B . n B 1 501 HIS 501 501 ? ? ? B . n B 1 502 ARG 502 502 ? ? ? B . n B 1 503 HIS 503 503 ? ? ? B . n B 1 504 HIS 504 504 ? ? ? B . n B 1 505 HIS 505 505 ? ? ? B . n B 1 506 HIS 506 506 ? ? ? B . n B 1 507 HIS 507 507 ? ? ? B . n B 1 508 HIS 508 508 ? ? ? B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 509 500 NAG NAG A . D 2 NAG 1 510 501 NAG NAG A . E 2 NAG 1 511 502 NAG NAG A . F 3 ZN 1 512 503 ZN ZN A . G 4 CFE 1 513 504 CFE CFE A . H 2 NAG 1 509 500 NAG NAG B . I 2 NAG 1 510 501 NAG NAG B . J 2 NAG 1 511 502 NAG NAG B . K 3 ZN 1 512 503 ZN ZN B . L 4 CFE 1 513 504 CFE CFE B . M 5 HOH 1 514 1 HOH HOH A . M 5 HOH 2 515 5 HOH HOH A . M 5 HOH 3 516 6 HOH HOH A . M 5 HOH 4 517 7 HOH HOH A . M 5 HOH 5 518 11 HOH HOH A . M 5 HOH 6 519 13 HOH HOH A . M 5 HOH 7 520 16 HOH HOH A . M 5 HOH 8 521 17 HOH HOH A . M 5 HOH 9 522 18 HOH HOH A . M 5 HOH 10 523 20 HOH HOH A . M 5 HOH 11 524 21 HOH HOH A . M 5 HOH 12 525 25 HOH HOH A . M 5 HOH 13 526 26 HOH HOH A . M 5 HOH 14 527 28 HOH HOH A . M 5 HOH 15 528 29 HOH HOH A . M 5 HOH 16 529 31 HOH HOH A . M 5 HOH 17 530 33 HOH HOH A . M 5 HOH 18 531 39 HOH HOH A . M 5 HOH 19 532 41 HOH HOH A . M 5 HOH 20 533 43 HOH HOH A . M 5 HOH 21 534 44 HOH HOH A . M 5 HOH 22 535 45 HOH HOH A . M 5 HOH 23 536 46 HOH HOH A . M 5 HOH 24 537 47 HOH HOH A . M 5 HOH 25 538 48 HOH HOH A . M 5 HOH 26 539 50 HOH HOH A . M 5 HOH 27 540 51 HOH HOH A . M 5 HOH 28 541 53 HOH HOH A . M 5 HOH 29 542 54 HOH HOH A . M 5 HOH 30 543 56 HOH HOH A . M 5 HOH 31 544 57 HOH HOH A . M 5 HOH 32 545 58 HOH HOH A . M 5 HOH 33 546 60 HOH HOH A . M 5 HOH 34 547 61 HOH HOH A . M 5 HOH 35 548 63 HOH HOH A . M 5 HOH 36 549 65 HOH HOH A . M 5 HOH 37 550 68 HOH HOH A . M 5 HOH 38 551 69 HOH HOH A . M 5 HOH 39 552 75 HOH HOH A . M 5 HOH 40 553 78 HOH HOH A . M 5 HOH 41 554 83 HOH HOH A . M 5 HOH 42 555 84 HOH HOH A . M 5 HOH 43 556 85 HOH HOH A . M 5 HOH 44 557 91 HOH HOH A . M 5 HOH 45 558 92 HOH HOH A . M 5 HOH 46 559 94 HOH HOH A . M 5 HOH 47 560 98 HOH HOH A . M 5 HOH 48 561 100 HOH HOH A . M 5 HOH 49 562 104 HOH HOH A . M 5 HOH 50 563 105 HOH HOH A . M 5 HOH 51 564 106 HOH HOH A . M 5 HOH 52 565 108 HOH HOH A . M 5 HOH 53 566 109 HOH HOH A . M 5 HOH 54 567 112 HOH HOH A . M 5 HOH 55 568 113 HOH HOH A . M 5 HOH 56 569 114 HOH HOH A . M 5 HOH 57 570 117 HOH HOH A . M 5 HOH 58 571 118 HOH HOH A . M 5 HOH 59 572 122 HOH HOH A . M 5 HOH 60 573 124 HOH HOH A . M 5 HOH 61 574 127 HOH HOH A . M 5 HOH 62 575 128 HOH HOH A . M 5 HOH 63 576 132 HOH HOH A . M 5 HOH 64 577 135 HOH HOH A . M 5 HOH 65 578 136 HOH HOH A . M 5 HOH 66 579 138 HOH HOH A . M 5 HOH 67 580 139 HOH HOH A . M 5 HOH 68 581 141 HOH HOH A . M 5 HOH 69 582 143 HOH HOH A . M 5 HOH 70 583 144 HOH HOH A . M 5 HOH 71 584 145 HOH HOH A . M 5 HOH 72 585 146 HOH HOH A . M 5 HOH 73 586 147 HOH HOH A . M 5 HOH 74 587 149 HOH HOH A . M 5 HOH 75 588 150 HOH HOH A . M 5 HOH 76 589 151 HOH HOH A . M 5 HOH 77 590 153 HOH HOH A . M 5 HOH 78 591 157 HOH HOH A . M 5 HOH 79 592 158 HOH HOH A . M 5 HOH 80 593 159 HOH HOH A . M 5 HOH 81 594 161 HOH HOH A . M 5 HOH 82 595 163 HOH HOH A . M 5 HOH 83 596 164 HOH HOH A . M 5 HOH 84 597 166 HOH HOH A . M 5 HOH 85 598 167 HOH HOH A . M 5 HOH 86 599 168 HOH HOH A . M 5 HOH 87 600 170 HOH HOH A . M 5 HOH 88 601 172 HOH HOH A . M 5 HOH 89 602 173 HOH HOH A . M 5 HOH 90 603 174 HOH HOH A . M 5 HOH 91 604 175 HOH HOH A . M 5 HOH 92 605 176 HOH HOH A . M 5 HOH 93 606 177 HOH HOH A . M 5 HOH 94 607 178 HOH HOH A . M 5 HOH 95 608 191 HOH HOH A . M 5 HOH 96 609 192 HOH HOH A . M 5 HOH 97 610 193 HOH HOH A . M 5 HOH 98 611 194 HOH HOH A . M 5 HOH 99 612 195 HOH HOH A . M 5 HOH 100 613 197 HOH HOH A . M 5 HOH 101 614 199 HOH HOH A . M 5 HOH 102 615 200 HOH HOH A . M 5 HOH 103 616 203 HOH HOH A . M 5 HOH 104 617 205 HOH HOH A . M 5 HOH 105 618 206 HOH HOH A . M 5 HOH 106 619 207 HOH HOH A . M 5 HOH 107 620 208 HOH HOH A . M 5 HOH 108 621 209 HOH HOH A . M 5 HOH 109 622 210 HOH HOH A . M 5 HOH 110 623 215 HOH HOH A . M 5 HOH 111 624 217 HOH HOH A . M 5 HOH 112 625 219 HOH HOH A . M 5 HOH 113 626 220 HOH HOH A . M 5 HOH 114 627 222 HOH HOH A . M 5 HOH 115 628 223 HOH HOH A . M 5 HOH 116 629 226 HOH HOH A . M 5 HOH 117 630 228 HOH HOH A . M 5 HOH 118 631 229 HOH HOH A . M 5 HOH 119 632 231 HOH HOH A . M 5 HOH 120 633 233 HOH HOH A . M 5 HOH 121 634 235 HOH HOH A . M 5 HOH 122 635 236 HOH HOH A . M 5 HOH 123 636 237 HOH HOH A . M 5 HOH 124 637 239 HOH HOH A . M 5 HOH 125 638 240 HOH HOH A . M 5 HOH 126 639 244 HOH HOH A . N 5 HOH 1 514 2 HOH HOH B . N 5 HOH 2 515 3 HOH HOH B . N 5 HOH 3 516 4 HOH HOH B . N 5 HOH 4 517 8 HOH HOH B . N 5 HOH 5 518 9 HOH HOH B . N 5 HOH 6 519 10 HOH HOH B . N 5 HOH 7 520 12 HOH HOH B . N 5 HOH 8 521 14 HOH HOH B . N 5 HOH 9 522 15 HOH HOH B . N 5 HOH 10 523 19 HOH HOH B . N 5 HOH 11 524 22 HOH HOH B . N 5 HOH 12 525 23 HOH HOH B . N 5 HOH 13 526 24 HOH HOH B . N 5 HOH 14 527 27 HOH HOH B . N 5 HOH 15 528 30 HOH HOH B . N 5 HOH 16 529 32 HOH HOH B . N 5 HOH 17 530 34 HOH HOH B . N 5 HOH 18 531 35 HOH HOH B . N 5 HOH 19 532 36 HOH HOH B . N 5 HOH 20 533 37 HOH HOH B . N 5 HOH 21 534 38 HOH HOH B . N 5 HOH 22 535 40 HOH HOH B . N 5 HOH 23 536 42 HOH HOH B . N 5 HOH 24 537 49 HOH HOH B . N 5 HOH 25 538 52 HOH HOH B . N 5 HOH 26 539 55 HOH HOH B . N 5 HOH 27 540 59 HOH HOH B . N 5 HOH 28 541 62 HOH HOH B . N 5 HOH 29 542 64 HOH HOH B . N 5 HOH 30 543 66 HOH HOH B . N 5 HOH 31 544 67 HOH HOH B . N 5 HOH 32 545 70 HOH HOH B . N 5 HOH 33 546 71 HOH HOH B . N 5 HOH 34 547 72 HOH HOH B . N 5 HOH 35 548 73 HOH HOH B . N 5 HOH 36 549 74 HOH HOH B . N 5 HOH 37 550 76 HOH HOH B . N 5 HOH 38 551 77 HOH HOH B . N 5 HOH 39 552 79 HOH HOH B . N 5 HOH 40 553 80 HOH HOH B . N 5 HOH 41 554 81 HOH HOH B . N 5 HOH 42 555 82 HOH HOH B . N 5 HOH 43 556 86 HOH HOH B . N 5 HOH 44 557 87 HOH HOH B . N 5 HOH 45 558 88 HOH HOH B . N 5 HOH 46 559 89 HOH HOH B . N 5 HOH 47 560 90 HOH HOH B . N 5 HOH 48 561 93 HOH HOH B . N 5 HOH 49 562 95 HOH HOH B . N 5 HOH 50 563 96 HOH HOH B . N 5 HOH 51 564 97 HOH HOH B . N 5 HOH 52 565 99 HOH HOH B . N 5 HOH 53 566 101 HOH HOH B . N 5 HOH 54 567 102 HOH HOH B . N 5 HOH 55 568 103 HOH HOH B . N 5 HOH 56 569 107 HOH HOH B . N 5 HOH 57 570 110 HOH HOH B . N 5 HOH 58 571 111 HOH HOH B . N 5 HOH 59 572 115 HOH HOH B . N 5 HOH 60 573 116 HOH HOH B . N 5 HOH 61 574 119 HOH HOH B . N 5 HOH 62 575 120 HOH HOH B . N 5 HOH 63 576 121 HOH HOH B . N 5 HOH 64 577 123 HOH HOH B . N 5 HOH 65 578 125 HOH HOH B . N 5 HOH 66 579 126 HOH HOH B . N 5 HOH 67 580 129 HOH HOH B . N 5 HOH 68 581 130 HOH HOH B . N 5 HOH 69 582 131 HOH HOH B . N 5 HOH 70 583 133 HOH HOH B . N 5 HOH 71 584 134 HOH HOH B . N 5 HOH 72 585 137 HOH HOH B . N 5 HOH 73 586 140 HOH HOH B . N 5 HOH 74 587 142 HOH HOH B . N 5 HOH 75 588 148 HOH HOH B . N 5 HOH 76 589 152 HOH HOH B . N 5 HOH 77 590 154 HOH HOH B . N 5 HOH 78 591 155 HOH HOH B . N 5 HOH 79 592 156 HOH HOH B . N 5 HOH 80 593 160 HOH HOH B . N 5 HOH 81 594 162 HOH HOH B . N 5 HOH 82 595 165 HOH HOH B . N 5 HOH 83 596 169 HOH HOH B . N 5 HOH 84 597 171 HOH HOH B . N 5 HOH 85 598 179 HOH HOH B . N 5 HOH 86 599 180 HOH HOH B . N 5 HOH 87 600 181 HOH HOH B . N 5 HOH 88 601 182 HOH HOH B . N 5 HOH 89 602 183 HOH HOH B . N 5 HOH 90 603 184 HOH HOH B . N 5 HOH 91 604 185 HOH HOH B . N 5 HOH 92 605 186 HOH HOH B . N 5 HOH 93 606 187 HOH HOH B . N 5 HOH 94 607 188 HOH HOH B . N 5 HOH 95 608 189 HOH HOH B . N 5 HOH 96 609 190 HOH HOH B . N 5 HOH 97 610 196 HOH HOH B . N 5 HOH 98 611 198 HOH HOH B . N 5 HOH 99 612 201 HOH HOH B . N 5 HOH 100 613 202 HOH HOH B . N 5 HOH 101 614 204 HOH HOH B . N 5 HOH 102 615 211 HOH HOH B . N 5 HOH 103 616 212 HOH HOH B . N 5 HOH 104 617 213 HOH HOH B . N 5 HOH 105 618 214 HOH HOH B . N 5 HOH 106 619 216 HOH HOH B . N 5 HOH 107 620 221 HOH HOH B . N 5 HOH 108 621 224 HOH HOH B . N 5 HOH 109 622 225 HOH HOH B . N 5 HOH 110 623 230 HOH HOH B . N 5 HOH 111 624 232 HOH HOH B . N 5 HOH 112 625 238 HOH HOH B . N 5 HOH 113 626 241 HOH HOH B . N 5 HOH 114 627 242 HOH HOH B . N 5 HOH 115 628 243 HOH HOH B . N 5 HOH 116 629 245 HOH HOH B . N 5 HOH 117 630 246 HOH HOH B . N 5 HOH 118 631 247 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 101 A ASN 101 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 159 A ASN 159 ? ASN 'GLYCOSYLATION SITE' 3 B ASN 101 B ASN 101 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 352 A ASN 352 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 352 B ASN 352 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 159 B ASN 159 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 6580 ? 1 MORE -7 ? 1 'SSA (A^2)' 38320 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O8 ? G CFE . ? A CFE 513 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 NE2 ? A HIS 88 ? A HIS 88 ? 1_555 111.1 ? 2 O8 ? G CFE . ? A CFE 513 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 NE2 ? A HIS 86 ? A HIS 86 ? 1_555 132.9 ? 3 NE2 ? A HIS 88 ? A HIS 88 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 NE2 ? A HIS 86 ? A HIS 86 ? 1_555 115.9 ? 4 O8 ? G CFE . ? A CFE 513 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 NE2 ? A HIS 330 ? A HIS 330 ? 1_555 89.1 ? 5 NE2 ? A HIS 88 ? A HIS 88 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 NE2 ? A HIS 330 ? A HIS 330 ? 1_555 95.6 ? 6 NE2 ? A HIS 86 ? A HIS 86 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 NE2 ? A HIS 330 ? A HIS 330 ? 1_555 88.0 ? 7 O8 ? G CFE . ? A CFE 513 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 OD1 ? A ASP 415 ? A ASP 415 ? 1_555 87.3 ? 8 NE2 ? A HIS 88 ? A HIS 88 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 OD1 ? A ASP 415 ? A ASP 415 ? 1_555 82.7 ? 9 NE2 ? A HIS 86 ? A HIS 86 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 OD1 ? A ASP 415 ? A ASP 415 ? 1_555 96.8 ? 10 NE2 ? A HIS 330 ? A HIS 330 ? 1_555 ZN ? F ZN . ? A ZN 512 ? 1_555 OD1 ? A ASP 415 ? A ASP 415 ? 1_555 175.2 ? 11 O8 ? L CFE . ? B CFE 513 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 NE2 ? B HIS 86 ? B HIS 86 ? 1_555 126.2 ? 12 O8 ? L CFE . ? B CFE 513 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 NE2 ? B HIS 88 ? B HIS 88 ? 1_555 109.9 ? 13 NE2 ? B HIS 86 ? B HIS 86 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 NE2 ? B HIS 88 ? B HIS 88 ? 1_555 122.4 ? 14 O8 ? L CFE . ? B CFE 513 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 NE2 ? B HIS 330 ? B HIS 330 ? 1_555 92.7 ? 15 NE2 ? B HIS 86 ? B HIS 86 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 NE2 ? B HIS 330 ? B HIS 330 ? 1_555 89.8 ? 16 NE2 ? B HIS 88 ? B HIS 88 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 NE2 ? B HIS 330 ? B HIS 330 ? 1_555 100.7 ? 17 O8 ? L CFE . ? B CFE 513 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 OD1 ? B ASP 415 ? B ASP 415 ? 1_555 82.7 ? 18 NE2 ? B HIS 86 ? B HIS 86 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 OD1 ? B ASP 415 ? B ASP 415 ? 1_555 92.1 ? 19 NE2 ? B HIS 88 ? B HIS 88 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 OD1 ? B ASP 415 ? B ASP 415 ? 1_555 82.0 ? 20 NE2 ? B HIS 330 ? B HIS 330 ? 1_555 ZN ? K ZN . ? B ZN 512 ? 1_555 OD1 ? B ASP 415 ? B ASP 415 ? 1_555 175.3 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-02-09 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal DNA 'data collection' . ? 1 PHENIX 'model building' . ? 2 REFMAC refinement 5.5.0102 ? 3 MOSFLM 'data reduction' . ? 4 SCALA 'data scaling' . ? 5 PHENIX phasing . ? 6 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 ND2 A ASN 159 ? ? C2 A NAG 510 ? ? 2.00 2 1 OE1 A GLU 218 ? ? NH2 A ARG 355 ? ? 2.11 3 1 OE1 B GLU 232 ? ? O B HOH 528 ? ? 2.18 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CZ _pdbx_validate_rmsd_bond.auth_asym_id_1 A _pdbx_validate_rmsd_bond.auth_comp_id_1 ARG _pdbx_validate_rmsd_bond.auth_seq_id_1 355 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 NH1 _pdbx_validate_rmsd_bond.auth_asym_id_2 A _pdbx_validate_rmsd_bond.auth_comp_id_2 ARG _pdbx_validate_rmsd_bond.auth_seq_id_2 355 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 ? _pdbx_validate_rmsd_bond.bond_value 1.241 _pdbx_validate_rmsd_bond.bond_target_value 1.326 _pdbx_validate_rmsd_bond.bond_deviation -0.085 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.013 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 NE A ARG 355 ? ? CZ A ARG 355 ? ? NH2 A ARG 355 ? ? 123.31 120.30 3.01 0.50 N 2 1 NE B ARG 355 ? ? CZ B ARG 355 ? ? NH2 B ARG 355 ? ? 124.29 120.30 3.99 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PRO A 114 ? ? -36.62 -38.03 2 1 SER A 130 ? ? -114.35 -160.27 3 1 LYS A 135 ? ? -168.16 115.33 4 1 HIS A 358 ? ? 77.53 -66.43 5 1 ASP A 415 ? ? 76.51 -77.27 6 1 ASP A 442 ? ? -126.62 -161.69 7 1 PRO B 114 ? ? -37.75 -36.14 8 1 LYS B 132 ? ? -166.90 1.43 9 1 CYS B 133 ? ? -165.21 101.93 10 1 HIS B 358 ? ? 77.38 -65.68 11 1 ASP B 415 ? ? 76.19 -78.74 12 1 ASP B 442 ? ? -126.57 -161.64 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C1 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id B _pdbx_validate_chiral.auth_comp_id NAG _pdbx_validate_chiral.auth_seq_id 509 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A LEU 157 ? CG ? A LEU 157 CG 2 1 Y 1 A LEU 157 ? CD1 ? A LEU 157 CD1 3 1 Y 1 A LEU 157 ? CD2 ? A LEU 157 CD2 4 1 Y 1 A LYS 324 ? CG ? A LYS 324 CG 5 1 Y 1 A LYS 324 ? CD ? A LYS 324 CD 6 1 Y 1 A LYS 324 ? CE ? A LYS 324 CE 7 1 Y 1 A LYS 324 ? NZ ? A LYS 324 NZ # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY 1 ? A GLY 1 2 1 Y 1 A GLY 2 ? A GLY 2 3 1 Y 1 A LYS 485 ? A LYS 485 4 1 Y 1 A GLY 486 ? A GLY 486 5 1 Y 1 A SER 487 ? A SER 487 6 1 Y 1 A LEU 488 ? A LEU 488 7 1 Y 1 A HIS 489 ? A HIS 489 8 1 Y 1 A HIS 490 ? A HIS 490 9 1 Y 1 A ILE 491 ? A ILE 491 10 1 Y 1 A LEU 492 ? A LEU 492 11 1 Y 1 A ASP 493 ? A ASP 493 12 1 Y 1 A ALA 494 ? A ALA 494 13 1 Y 1 A GLN 495 ? A GLN 495 14 1 Y 1 A LYS 496 ? A LYS 496 15 1 Y 1 A MET 497 ? A MET 497 16 1 Y 1 A VAL 498 ? A VAL 498 17 1 Y 1 A TRP 499 ? A TRP 499 18 1 Y 1 A ASN 500 ? A ASN 500 19 1 Y 1 A HIS 501 ? A HIS 501 20 1 Y 1 A ARG 502 ? A ARG 502 21 1 Y 1 A HIS 503 ? A HIS 503 22 1 Y 1 A HIS 504 ? A HIS 504 23 1 Y 1 A HIS 505 ? A HIS 505 24 1 Y 1 A HIS 506 ? A HIS 506 25 1 Y 1 A HIS 507 ? A HIS 507 26 1 Y 1 A HIS 508 ? A HIS 508 27 1 Y 1 B GLY 1 ? B GLY 1 28 1 Y 1 B GLY 2 ? B GLY 2 29 1 Y 1 B LYS 485 ? B LYS 485 30 1 Y 1 B GLY 486 ? B GLY 486 31 1 Y 1 B SER 487 ? B SER 487 32 1 Y 1 B LEU 488 ? B LEU 488 33 1 Y 1 B HIS 489 ? B HIS 489 34 1 Y 1 B HIS 490 ? B HIS 490 35 1 Y 1 B ILE 491 ? B ILE 491 36 1 Y 1 B LEU 492 ? B LEU 492 37 1 Y 1 B ASP 493 ? B ASP 493 38 1 Y 1 B ALA 494 ? B ALA 494 39 1 Y 1 B GLN 495 ? B GLN 495 40 1 Y 1 B LYS 496 ? B LYS 496 41 1 Y 1 B MET 497 ? B MET 497 42 1 Y 1 B VAL 498 ? B VAL 498 43 1 Y 1 B TRP 499 ? B TRP 499 44 1 Y 1 B ASN 500 ? B ASN 500 45 1 Y 1 B HIS 501 ? B HIS 501 46 1 Y 1 B ARG 502 ? B ARG 502 47 1 Y 1 B HIS 503 ? B HIS 503 48 1 Y 1 B HIS 504 ? B HIS 504 49 1 Y 1 B HIS 505 ? B HIS 505 50 1 Y 1 B HIS 506 ? B HIS 506 51 1 Y 1 B HIS 507 ? B HIS 507 52 1 Y 1 B HIS 508 ? B HIS 508 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 '(8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol' CFE 5 water HOH #