data_3LAQ # _entry.id 3LAQ # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.281 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3LAQ RCSB RCSB057045 WWPDB D_1000057045 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 2FD6 . unspecified PDB 3BT1 . unspecified PDB 3BT2 . unspecified PDB 2FAT . unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3LAQ _pdbx_database_status.recvd_initial_deposition_date 2010-01-06 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # _audit_author.name 'Huang, M.' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title ;Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy. ; _citation.journal_abbrev J.Biol.Chem. _citation.journal_volume 285 _citation.page_first 10982 _citation.page_last 10992 _citation.year 2010 _citation.journal_id_ASTM JBCHA3 _citation.country US _citation.journal_id_ISSN 0021-9258 _citation.journal_id_CSD 0071 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20133942 _citation.pdbx_database_id_DOI 10.1074/jbc.M109.093492 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Lin, L.' 1 primary 'Gardsvoll, H.' 2 primary 'Huai, Q.' 3 primary 'Huang, M.' 4 primary 'Ploug, M.' 5 # _cell.entry_id 3LAQ _cell.length_a 61.421 _cell.length_b 137.248 _cell.length_c 65.785 _cell.angle_alpha 90.00 _cell.angle_beta 106.17 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3LAQ _symmetry.space_group_name_H-M 'P 1 21 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 4 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Urokinase-type plasminogen activator' 14997.969 2 3.4.21.73 ? 'UNP residues 21-154' ? 2 polymer man 'Urokinase plasminogen activator surface receptor' 30170.777 2 ? ? 'UNP residues 24-300' ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 10 ? ? ? ? # loop_ _entity_name_com.entity_id _entity_name_com.name 1 ;U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B ; 2 'uPAR, U-PAR' # loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 'polypeptide(L)' no no ;GSVLGAPDESNCGCQNGGVCVSYKYFSRIRRCSCPRKFQGEHCEIDASKTCYHGNGDSYRGKANTDTKGRPCLAWNAPAV LQKPYNAHRPDAISLGLGKHNYCRNPDNQKRPWCYVQIGLRQFVQECMVHDCSL ; ;GSVLGAPDESNCGCQNGGVCVSYKYFSRIRRCSCPRKFQGEHCEIDASKTCYHGNGDSYRGKANTDTKGRPCLAWNAPAV LQKPYNAHRPDAISLGLGKHNYCRNPDNQKRPWCYVQIGLRQFVQECMVHDCSL ; A,B ? 2 'polypeptide(L)' no no ;LQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPR PGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSN QTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCA TASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPTGGA ; ;LQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPR PGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSN QTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCA TASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPTGGA ; U,V ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 GLY n 1 2 SER n 1 3 VAL n 1 4 LEU n 1 5 GLY n 1 6 ALA n 1 7 PRO n 1 8 ASP n 1 9 GLU n 1 10 SER n 1 11 ASN n 1 12 CYS n 1 13 GLY n 1 14 CYS n 1 15 GLN n 1 16 ASN n 1 17 GLY n 1 18 GLY n 1 19 VAL n 1 20 CYS n 1 21 VAL n 1 22 SER n 1 23 TYR n 1 24 LYS n 1 25 TYR n 1 26 PHE n 1 27 SER n 1 28 ARG n 1 29 ILE n 1 30 ARG n 1 31 ARG n 1 32 CYS n 1 33 SER n 1 34 CYS n 1 35 PRO n 1 36 ARG n 1 37 LYS n 1 38 PHE n 1 39 GLN n 1 40 GLY n 1 41 GLU n 1 42 HIS n 1 43 CYS n 1 44 GLU n 1 45 ILE n 1 46 ASP n 1 47 ALA n 1 48 SER n 1 49 LYS n 1 50 THR n 1 51 CYS n 1 52 TYR n 1 53 HIS n 1 54 GLY n 1 55 ASN n 1 56 GLY n 1 57 ASP n 1 58 SER n 1 59 TYR n 1 60 ARG n 1 61 GLY n 1 62 LYS n 1 63 ALA n 1 64 ASN n 1 65 THR n 1 66 ASP n 1 67 THR n 1 68 LYS n 1 69 GLY n 1 70 ARG n 1 71 PRO n 1 72 CYS n 1 73 LEU n 1 74 ALA n 1 75 TRP n 1 76 ASN n 1 77 ALA n 1 78 PRO n 1 79 ALA n 1 80 VAL n 1 81 LEU n 1 82 GLN n 1 83 LYS n 1 84 PRO n 1 85 TYR n 1 86 ASN n 1 87 ALA n 1 88 HIS n 1 89 ARG n 1 90 PRO n 1 91 ASP n 1 92 ALA n 1 93 ILE n 1 94 SER n 1 95 LEU n 1 96 GLY n 1 97 LEU n 1 98 GLY n 1 99 LYS n 1 100 HIS n 1 101 ASN n 1 102 TYR n 1 103 CYS n 1 104 ARG n 1 105 ASN n 1 106 PRO n 1 107 ASP n 1 108 ASN n 1 109 GLN n 1 110 LYS n 1 111 ARG n 1 112 PRO n 1 113 TRP n 1 114 CYS n 1 115 TYR n 1 116 VAL n 1 117 GLN n 1 118 ILE n 1 119 GLY n 1 120 LEU n 1 121 ARG n 1 122 GLN n 1 123 PHE n 1 124 VAL n 1 125 GLN n 1 126 GLU n 1 127 CYS n 1 128 MET n 1 129 VAL n 1 130 HIS n 1 131 ASP n 1 132 CYS n 1 133 SER n 1 134 LEU n 2 1 LEU n 2 2 GLN n 2 3 CYS n 2 4 MET n 2 5 GLN n 2 6 CYS n 2 7 GLU n 2 8 SER n 2 9 ASN n 2 10 GLN n 2 11 SER n 2 12 CYS n 2 13 LEU n 2 14 VAL n 2 15 GLU n 2 16 GLU n 2 17 CYS n 2 18 ALA n 2 19 LEU n 2 20 GLY n 2 21 GLN n 2 22 ASP n 2 23 LEU n 2 24 CYS n 2 25 ARG n 2 26 THR n 2 27 THR n 2 28 VAL n 2 29 LEU n 2 30 ARG n 2 31 GLU n 2 32 TRP n 2 33 GLN n 2 34 ASP n 2 35 ASP n 2 36 ARG n 2 37 GLU n 2 38 LEU n 2 39 GLU n 2 40 VAL n 2 41 VAL n 2 42 THR n 2 43 ARG n 2 44 GLY n 2 45 CYS n 2 46 ALA n 2 47 HIS n 2 48 SER n 2 49 GLU n 2 50 LYS n 2 51 THR n 2 52 ASN n 2 53 ARG n 2 54 THR n 2 55 MET n 2 56 SER n 2 57 TYR n 2 58 ARG n 2 59 MET n 2 60 GLY n 2 61 SER n 2 62 MET n 2 63 ILE n 2 64 ILE n 2 65 SER n 2 66 LEU n 2 67 THR n 2 68 GLU n 2 69 THR n 2 70 VAL n 2 71 CYS n 2 72 ALA n 2 73 THR n 2 74 ASN n 2 75 LEU n 2 76 CYS n 2 77 ASN n 2 78 ARG n 2 79 PRO n 2 80 ARG n 2 81 PRO n 2 82 GLY n 2 83 ALA n 2 84 ARG n 2 85 GLY n 2 86 ARG n 2 87 ALA n 2 88 PHE n 2 89 PRO n 2 90 GLN n 2 91 GLY n 2 92 ARG n 2 93 TYR n 2 94 LEU n 2 95 GLU n 2 96 CYS n 2 97 ALA n 2 98 SER n 2 99 CYS n 2 100 THR n 2 101 SER n 2 102 LEU n 2 103 ASP n 2 104 GLN n 2 105 SER n 2 106 CYS n 2 107 GLU n 2 108 ARG n 2 109 GLY n 2 110 ARG n 2 111 GLU n 2 112 GLN n 2 113 SER n 2 114 LEU n 2 115 GLN n 2 116 CYS n 2 117 ARG n 2 118 TYR n 2 119 PRO n 2 120 THR n 2 121 GLU n 2 122 HIS n 2 123 CYS n 2 124 ILE n 2 125 GLU n 2 126 VAL n 2 127 VAL n 2 128 THR n 2 129 LEU n 2 130 GLN n 2 131 SER n 2 132 THR n 2 133 GLU n 2 134 ARG n 2 135 SER n 2 136 LEU n 2 137 LYS n 2 138 ASP n 2 139 GLU n 2 140 ASP n 2 141 TYR n 2 142 THR n 2 143 ARG n 2 144 GLY n 2 145 CYS n 2 146 GLY n 2 147 SER n 2 148 LEU n 2 149 PRO n 2 150 GLY n 2 151 CYS n 2 152 PRO n 2 153 GLY n 2 154 THR n 2 155 ALA n 2 156 GLY n 2 157 PHE n 2 158 HIS n 2 159 SER n 2 160 ASN n 2 161 GLN n 2 162 THR n 2 163 PHE n 2 164 HIS n 2 165 PHE n 2 166 LEU n 2 167 LYS n 2 168 CYS n 2 169 CYS n 2 170 ASN n 2 171 TYR n 2 172 THR n 2 173 HIS n 2 174 CYS n 2 175 ASN n 2 176 GLY n 2 177 GLY n 2 178 PRO n 2 179 VAL n 2 180 LEU n 2 181 ASP n 2 182 LEU n 2 183 GLN n 2 184 SER n 2 185 PHE n 2 186 PRO n 2 187 PRO n 2 188 ASN n 2 189 GLY n 2 190 PHE n 2 191 GLN n 2 192 CYS n 2 193 TYR n 2 194 SER n 2 195 CYS n 2 196 GLU n 2 197 GLY n 2 198 ASN n 2 199 ASN n 2 200 THR n 2 201 LEU n 2 202 GLY n 2 203 CYS n 2 204 SER n 2 205 SER n 2 206 GLU n 2 207 GLU n 2 208 ALA n 2 209 SER n 2 210 LEU n 2 211 ILE n 2 212 ASN n 2 213 CYS n 2 214 ARG n 2 215 GLY n 2 216 PRO n 2 217 MET n 2 218 ASN n 2 219 GLN n 2 220 CYS n 2 221 LEU n 2 222 VAL n 2 223 ALA n 2 224 THR n 2 225 GLY n 2 226 LEU n 2 227 ASP n 2 228 VAL n 2 229 LEU n 2 230 GLY n 2 231 ASN n 2 232 ARG n 2 233 SER n 2 234 TYR n 2 235 THR n 2 236 VAL n 2 237 ARG n 2 238 GLY n 2 239 CYS n 2 240 ALA n 2 241 THR n 2 242 ALA n 2 243 SER n 2 244 TRP n 2 245 CYS n 2 246 GLN n 2 247 GLY n 2 248 SER n 2 249 HIS n 2 250 VAL n 2 251 ALA n 2 252 ASP n 2 253 SER n 2 254 PHE n 2 255 PRO n 2 256 THR n 2 257 HIS n 2 258 LEU n 2 259 ASN n 2 260 VAL n 2 261 SER n 2 262 VAL n 2 263 SER n 2 264 CYS n 2 265 CYS n 2 266 HIS n 2 267 GLY n 2 268 SER n 2 269 GLY n 2 270 CYS n 2 271 ASN n 2 272 SER n 2 273 PRO n 2 274 THR n 2 275 GLY n 2 276 GLY n 2 277 ALA n # loop_ _entity_src_gen.entity_id _entity_src_gen.pdbx_src_id _entity_src_gen.pdbx_alt_source_flag _entity_src_gen.pdbx_seq_type _entity_src_gen.pdbx_beg_seq_num _entity_src_gen.pdbx_end_seq_num _entity_src_gen.gene_src_common_name _entity_src_gen.gene_src_genus _entity_src_gen.pdbx_gene_src_gene _entity_src_gen.gene_src_species _entity_src_gen.gene_src_strain _entity_src_gen.gene_src_tissue _entity_src_gen.gene_src_tissue_fraction _entity_src_gen.gene_src_details _entity_src_gen.pdbx_gene_src_fragment _entity_src_gen.pdbx_gene_src_scientific_name _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id _entity_src_gen.pdbx_gene_src_variant _entity_src_gen.pdbx_gene_src_cell_line _entity_src_gen.pdbx_gene_src_atcc _entity_src_gen.pdbx_gene_src_organ _entity_src_gen.pdbx_gene_src_organelle _entity_src_gen.pdbx_gene_src_cell _entity_src_gen.pdbx_gene_src_cellular_location _entity_src_gen.host_org_common_name _entity_src_gen.pdbx_host_org_scientific_name _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id _entity_src_gen.host_org_genus _entity_src_gen.pdbx_host_org_gene _entity_src_gen.pdbx_host_org_organ _entity_src_gen.host_org_species _entity_src_gen.pdbx_host_org_tissue _entity_src_gen.pdbx_host_org_tissue_fraction _entity_src_gen.pdbx_host_org_strain _entity_src_gen.pdbx_host_org_variant _entity_src_gen.pdbx_host_org_cell_line _entity_src_gen.pdbx_host_org_atcc _entity_src_gen.pdbx_host_org_culture_collection _entity_src_gen.pdbx_host_org_cell _entity_src_gen.pdbx_host_org_organelle _entity_src_gen.pdbx_host_org_cellular_location _entity_src_gen.pdbx_host_org_vector_type _entity_src_gen.pdbx_host_org_vector _entity_src_gen.host_org_details _entity_src_gen.expression_system_id _entity_src_gen.plasmid_name _entity_src_gen.plasmid_details _entity_src_gen.pdbx_description 1 1 sample ? ? ? mouse ? Plau ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? Drosophila 7215 ? ? ? ? ? ? 'S2 cells' ? ? ? ? ? ? ? plasmid ? ? ? pMT ? ? 2 1 sample ? ? ? mouse ? Plaur ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? Drosophila 7215 ? ? ? ? ? ? 'S2 cells' ? ? ? ? ? ? ? plasmid ? ? ? pMT ? ? # loop_ _struct_ref.id _struct_ref.db_name _struct_ref.db_code _struct_ref.pdbx_db_accession _struct_ref.entity_id _struct_ref.pdbx_seq_one_letter_code _struct_ref.pdbx_align_begin _struct_ref.pdbx_db_isoform 1 UNP UROK_MOUSE P06869 1 ;GSVLGAPDESNCGCQNGGVCVSYKYFSRIRRCSCPRKFQGEHCEIDASKTCYHGNGDSYRGKANTDTKGRPCLAWNAPAV LQKPYNAHRPDAISLGLGKHNYCRNPDNQKRPWCYVQIGLRQFVQECMVHDCSL ; 21 ? 2 UNP UPAR_MOUSE P35456 2 ;LQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPR PGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSN QTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCA TASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPTGGA ; 24 ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3LAQ A 1 ? 134 ? P06869 21 ? 154 ? 1 134 2 2 3LAQ U 1 ? 277 ? P35456 24 ? 300 ? 1 277 3 1 3LAQ B 1 ? 134 ? P06869 21 ? 154 ? 1 134 4 2 3LAQ V 1 ? 277 ? P35456 24 ? 300 ? 1 277 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3LAQ _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.95 _exptl_crystal.density_percent_sol 58.28 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, SITTING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 5.5 _exptl_crystal_grow.pdbx_pH_range ? _exptl_crystal_grow.pdbx_details '5-7 % (w/v) PEG 3350, 50 mM Bis-Tris at pH 5.5., VAPOR DIFFUSION, SITTING DROP, temperature 293K' # _diffrn.id 1 _diffrn.ambient_temp 160 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.pdbx_collection_date 2006-08 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator GRAPHITE _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'NSLS BEAMLINE X29A' _diffrn_source.pdbx_synchrotron_site NSLS _diffrn_source.pdbx_synchrotron_beamline X29A _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.0 # _reflns.entry_id 3LAQ _reflns.observed_criterion_sigma_I 0 _reflns.observed_criterion_sigma_F 0 _reflns.d_resolution_low 50 _reflns.d_resolution_high 3.2 _reflns.number_obs 17190 _reflns.number_all ? _reflns.percent_possible_obs 89.5 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 3.2 _reflns_shell.d_res_low 3.21 _reflns_shell.percent_possible_all 54.4 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.entry_id 3LAQ _refine.ls_number_reflns_obs 15297 _refine.ls_number_reflns_all 14272 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F 0.000 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 44.74 _refine.ls_d_res_high 3.20 _refine.ls_percent_reflns_obs 93.3 _refine.ls_R_factor_obs 0.237 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.231 _refine.ls_R_factor_R_free 0.341 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.300 _refine.ls_number_reflns_R_free 853 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.894 _refine.correlation_coeff_Fo_to_Fc_free 0.771 _refine.B_iso_mean 34.72 _refine.aniso_B[1][1] 2.02000 _refine.aniso_B[2][2] -2.84000 _refine.aniso_B[3][3] 0.39000 _refine.aniso_B[1][2] 0.00000 _refine.aniso_B[1][3] -0.77000 _refine.aniso_B[2][3] 0.00000 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free 0.715 _refine.overall_SU_ML 0.577 _refine.pdbx_overall_phase_error ? _refine.overall_SU_B 70.075 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_TLS_residual_ADP_flag 'LIKELY RESIDUAL' _refine.pdbx_diffrn_id 1 _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 5895 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 140 _refine_hist.number_atoms_solvent 0 _refine_hist.number_atoms_total 6035 _refine_hist.d_res_high 3.20 _refine_hist.d_res_low 44.74 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.014 0.021 ? 6203 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.800 1.967 ? 8419 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 8.270 5.000 ? 758 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 39.794 23.741 ? 294 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 24.301 15.000 ? 984 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 21.217 15.000 ? 52 'X-RAY DIFFRACTION' ? r_chiral_restr 0.122 0.200 ? 905 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.008 0.021 ? 4776 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.547 1.500 ? 3803 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.120 2.000 ? 6108 'X-RAY DIFFRACTION' ? r_scbond_it 1.739 3.000 ? 2400 'X-RAY DIFFRACTION' ? r_scangle_it 3.092 4.500 ? 2311 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 3.20 _refine_ls_shell.d_res_low 3.28 _refine_ls_shell.number_reflns_R_work 760 _refine_ls_shell.R_factor_R_work 0.2560 _refine_ls_shell.percent_reflns_obs 63.27 _refine_ls_shell.R_factor_R_free 0.3800 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 48 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.number_reflns_obs ? # _pdbx_refine.pdbx_refine_id 'X-RAY DIFFRACTION' _pdbx_refine.entry_id 3LAQ _pdbx_refine.R_factor_all_no_cutoff ? _pdbx_refine.R_factor_obs_no_cutoff ? _pdbx_refine.free_R_factor_no_cutoff ? _pdbx_refine.free_R_error_no_cutoff ? _pdbx_refine.free_R_val_test_set_size_perc_no_cutoff ? _pdbx_refine.free_R_val_test_set_ct_no_cutoff ? _pdbx_refine.R_factor_all_4sig_cutoff ? _pdbx_refine.R_factor_obs_4sig_cutoff ? _pdbx_refine.free_R_factor_4sig_cutoff ? _pdbx_refine.free_R_val_test_set_size_perc_4sig_cutoff ? _pdbx_refine.free_R_val_test_set_ct_4sig_cutoff ? _pdbx_refine.number_reflns_obs_4sig_cutoff ? # _struct.entry_id 3LAQ _struct.title 'Structure-based engineering of species selectivity in the uPA-uPAR interaction' _struct.pdbx_descriptor 'Urokinase-type plasminogen activator (E.C.3.4.21.73), Urokinase plasminogen activator surface receptor' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3LAQ _struct_keywords.pdbx_keywords 'Hydrolase/Hydrolase Receptor' _struct_keywords.text ;uPA, uPAR, ATF, suPAR, smuPAR, mATF, Disulfide bond, EGF-like domain, Hydrolase, Kringle, Plasminogen activation, Protease, Secreted, Serine protease, Zymogen, Cell membrane, Glycoprotein, GPI-anchor, Lipoprotein, Membrane, Receptor, Hydrolase-Hydrolase Receptor complex ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 1 ? D N N 2 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 3 ? I N N 3 ? J N N 3 ? K N N 3 ? L N N 3 ? M N N 3 ? N N N 3 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 LYS A 24 ? SER A 27 ? LYS A 24 SER A 27 5 ? 4 HELX_P HELX_P2 2 ALA A 79 ? LYS A 83 ? ALA A 79 LYS A 83 5 ? 5 HELX_P HELX_P3 3 SER B 248 ? SER B 253 ? SER U 248 SER U 253 1 ? 6 HELX_P HELX_P4 4 SER B 268 ? SER B 272 ? SER U 268 SER U 272 5 ? 5 HELX_P HELX_P5 5 ALA C 77 ? GLN C 82 ? ALA B 77 GLN B 82 1 ? 6 HELX_P HELX_P6 6 ASP C 91 ? LEU C 95 ? ASP B 91 LEU B 95 5 ? 5 HELX_P HELX_P7 7 LEU D 102 ? GLN D 104 ? LEU V 102 GLN V 104 5 ? 3 HELX_P HELX_P8 8 VAL D 250 ? PHE D 254 ? VAL V 250 PHE V 254 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 12 SG ? ? ? 1_555 A CYS 20 SG ? ? A CYS 12 A CYS 20 1_555 ? ? ? ? ? ? ? 2.059 ? disulf2 disulf ? ? A CYS 14 SG ? ? ? 1_555 A CYS 32 SG ? ? A CYS 14 A CYS 32 1_555 ? ? ? ? ? ? ? 2.044 ? disulf3 disulf ? ? A CYS 34 SG ? ? ? 1_555 A CYS 43 SG ? ? A CYS 34 A CYS 43 1_555 ? ? ? ? ? ? ? 2.074 ? disulf4 disulf ? ? A CYS 51 SG ? ? ? 1_555 A CYS 132 SG ? ? A CYS 51 A CYS 132 1_555 ? ? ? ? ? ? ? 2.100 ? disulf5 disulf ? ? A CYS 72 SG ? ? ? 1_555 A CYS 114 SG ? ? A CYS 72 A CYS 114 1_555 ? ? ? ? ? ? ? 2.027 ? disulf6 disulf ? ? A CYS 103 SG ? ? ? 1_555 A CYS 127 SG ? ? A CYS 103 A CYS 127 1_555 ? ? ? ? ? ? ? 2.044 ? disulf7 disulf ? ? B CYS 3 SG ? ? ? 1_555 B CYS 24 SG ? ? U CYS 3 U CYS 24 1_555 ? ? ? ? ? ? ? 2.005 ? disulf8 disulf ? ? B CYS 6 SG ? ? ? 1_555 B CYS 12 SG ? ? U CYS 6 U CYS 12 1_555 ? ? ? ? ? ? ? 2.114 ? disulf9 disulf ? ? B CYS 17 SG ? ? ? 1_555 B CYS 45 SG ? ? U CYS 17 U CYS 45 1_555 ? ? ? ? ? ? ? 2.069 ? disulf10 disulf ? ? B CYS 71 SG ? ? ? 1_555 B CYS 76 SG ? ? U CYS 71 U CYS 76 1_555 ? ? ? ? ? ? ? 2.069 ? disulf11 disulf ? ? B CYS 96 SG ? ? ? 1_555 B CYS 123 SG ? ? U CYS 96 U CYS 123 1_555 ? ? ? ? ? ? ? 2.061 ? disulf12 disulf ? ? B CYS 99 SG ? ? ? 1_555 B CYS 106 SG ? ? U CYS 99 U CYS 106 1_555 ? ? ? ? ? ? ? 2.052 ? disulf13 disulf ? ? B CYS 116 SG ? ? ? 1_555 B CYS 145 SG ? ? U CYS 116 U CYS 145 1_555 ? ? ? ? ? ? ? 2.055 ? disulf14 disulf ? ? B CYS 151 SG ? ? ? 1_555 B CYS 168 SG ? ? U CYS 151 U CYS 168 1_555 ? ? ? ? ? ? ? 2.053 ? disulf15 disulf ? ? B CYS 169 SG ? ? ? 1_555 B CYS 174 SG ? ? U CYS 169 U CYS 174 1_555 ? ? ? ? ? ? ? 2.034 ? disulf16 disulf ? ? B CYS 192 SG ? ? ? 1_555 B CYS 220 SG ? ? U CYS 192 U CYS 220 1_555 ? ? ? ? ? ? ? 2.043 ? disulf17 disulf ? ? B CYS 195 SG ? ? ? 1_555 B CYS 203 SG ? ? U CYS 195 U CYS 203 1_555 ? ? ? ? ? ? ? 2.032 ? disulf18 disulf ? ? B CYS 213 SG ? ? ? 1_555 B CYS 239 SG ? ? U CYS 213 U CYS 239 1_555 ? ? ? ? ? ? ? 2.046 ? disulf19 disulf ? ? B CYS 245 SG ? ? ? 1_555 B CYS 264 SG ? ? U CYS 245 U CYS 264 1_555 ? ? ? ? ? ? ? 2.046 ? disulf20 disulf ? ? B CYS 265 SG ? ? ? 1_555 B CYS 270 SG ? ? U CYS 265 U CYS 270 1_555 ? ? ? ? ? ? ? 2.043 ? disulf21 disulf ? ? C CYS 12 SG ? ? ? 1_555 C CYS 20 SG ? ? B CYS 12 B CYS 20 1_555 ? ? ? ? ? ? ? 2.061 ? disulf22 disulf ? ? C CYS 14 SG ? ? ? 1_555 C CYS 32 SG ? ? B CYS 14 B CYS 32 1_555 ? ? ? ? ? ? ? 2.081 ? disulf23 disulf ? ? C CYS 34 SG ? ? ? 1_555 C CYS 43 SG ? ? B CYS 34 B CYS 43 1_555 ? ? ? ? ? ? ? 2.067 ? disulf24 disulf ? ? C CYS 51 SG ? ? ? 1_555 C CYS 132 SG ? ? B CYS 51 B CYS 132 1_555 ? ? ? ? ? ? ? 2.042 ? disulf25 disulf ? ? C CYS 72 SG ? ? ? 1_555 C CYS 114 SG ? ? B CYS 72 B CYS 114 1_555 ? ? ? ? ? ? ? 2.047 ? disulf26 disulf ? ? C CYS 103 SG ? ? ? 1_555 C CYS 127 SG ? ? B CYS 103 B CYS 127 1_555 ? ? ? ? ? ? ? 2.050 ? disulf27 disulf ? ? D CYS 3 SG ? ? ? 1_555 D CYS 24 SG ? ? V CYS 3 V CYS 24 1_555 ? ? ? ? ? ? ? 2.069 ? disulf28 disulf ? ? D CYS 6 SG ? ? ? 1_555 D CYS 12 SG ? ? V CYS 6 V CYS 12 1_555 ? ? ? ? ? ? ? 2.158 ? disulf29 disulf ? ? D CYS 17 SG ? ? ? 1_555 D CYS 45 SG ? ? V CYS 17 V CYS 45 1_555 ? ? ? ? ? ? ? 2.078 ? disulf30 disulf ? ? D CYS 71 SG ? ? ? 1_555 D CYS 76 SG ? ? V CYS 71 V CYS 76 1_555 ? ? ? ? ? ? ? 2.019 ? disulf31 disulf ? ? D CYS 96 SG ? ? ? 1_555 D CYS 123 SG ? ? V CYS 96 V CYS 123 1_555 ? ? ? ? ? ? ? 2.037 ? disulf32 disulf ? ? D CYS 99 SG ? ? ? 1_555 D CYS 106 SG ? ? V CYS 99 V CYS 106 1_555 ? ? ? ? ? ? ? 2.044 ? disulf33 disulf ? ? D CYS 116 SG ? ? ? 1_555 D CYS 145 SG ? ? V CYS 116 V CYS 145 1_555 ? ? ? ? ? ? ? 2.047 ? disulf34 disulf ? ? D CYS 151 SG ? ? ? 1_555 D CYS 168 SG ? ? V CYS 151 V CYS 168 1_555 ? ? ? ? ? ? ? 2.064 ? disulf35 disulf ? ? D CYS 169 SG ? ? ? 1_555 D CYS 174 SG ? ? V CYS 169 V CYS 174 1_555 ? ? ? ? ? ? ? 2.027 ? disulf36 disulf ? ? D CYS 192 SG ? ? ? 1_555 D CYS 220 SG ? ? V CYS 192 V CYS 220 1_555 ? ? ? ? ? ? ? 2.057 ? disulf37 disulf ? ? D CYS 195 SG ? ? ? 1_555 D CYS 203 SG ? ? V CYS 195 V CYS 203 1_555 ? ? ? ? ? ? ? 2.050 ? disulf38 disulf ? ? D CYS 213 SG ? ? ? 1_555 D CYS 239 SG ? ? V CYS 213 V CYS 239 1_555 ? ? ? ? ? ? ? 2.056 ? disulf39 disulf ? ? D CYS 245 SG ? ? ? 1_555 D CYS 264 SG ? ? V CYS 245 V CYS 264 1_555 ? ? ? ? ? ? ? 2.081 ? disulf40 disulf ? ? D CYS 265 SG ? ? ? 1_555 D CYS 270 SG ? ? V CYS 265 V CYS 270 1_555 ? ? ? ? ? ? ? 2.026 ? covale1 covale ? ? B ASN 52 ND2 ? ? ? 1_555 E NAG . C1 ? ? U ASN 52 U NAG 1052 1_555 ? ? ? ? ? ? ? 1.312 ? covale2 covale ? ? B ASN 170 ND2 ? ? ? 1_555 H NAG . C1 ? ? U ASN 170 U NAG 1170 1_555 ? ? ? ? ? ? ? 1.346 ? covale3 covale ? ? D ASN 52 ND2 ? ? ? 1_555 J NAG . C1 ? ? V ASN 52 V NAG 1052 1_555 ? ? ? ? ? ? ? 1.430 ? covale4 covale ? ? D ASN 160 ND2 ? ? ? 1_555 M NAG . C1 ? ? V ASN 160 V NAG 1160 1_555 ? ? ? ? ? ? ? 1.438 ? covale5 covale ? ? B ASN 259 ND2 ? ? ? 1_555 I NAG . C1 ? ? U ASN 259 U NAG 1259 1_555 ? ? ? ? ? ? ? 1.446 ? covale6 covale ? ? D ASN 259 ND2 ? ? ? 1_555 N NAG . C1 ? ? V ASN 259 V NAG 1259 1_555 ? ? ? ? ? ? ? 1.454 ? covale7 covale ? ? D ASN 170 ND2 ? ? ? 1_555 L NAG . C1 ? ? V ASN 170 V NAG 1170 1_555 ? ? ? ? ? ? ? 1.557 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 2 ? C ? 2 ? D ? 2 ? E ? 6 ? F ? 11 ? G ? 2 ? H ? 2 ? I ? 2 ? J ? 2 ? K ? 2 ? L ? 2 ? M ? 6 ? N ? 11 ? O ? 2 ? P ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? anti-parallel C 1 2 ? anti-parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel F 5 6 ? anti-parallel F 6 7 ? anti-parallel F 7 8 ? anti-parallel F 8 9 ? anti-parallel F 9 10 ? anti-parallel F 10 11 ? anti-parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel K 1 2 ? anti-parallel L 1 2 ? anti-parallel M 1 2 ? anti-parallel M 2 3 ? anti-parallel M 3 4 ? anti-parallel M 4 5 ? anti-parallel M 5 6 ? anti-parallel N 1 2 ? anti-parallel N 2 3 ? anti-parallel N 3 4 ? anti-parallel N 4 5 ? anti-parallel N 5 6 ? anti-parallel N 6 7 ? anti-parallel N 7 8 ? anti-parallel N 8 9 ? anti-parallel N 9 10 ? anti-parallel N 10 11 ? anti-parallel O 1 2 ? anti-parallel P 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 CYS A 20 ? SER A 22 ? CYS A 20 SER A 22 A 2 ARG A 30 ? CYS A 32 ? ARG A 30 CYS A 32 B 1 PHE A 38 ? GLN A 39 ? PHE A 38 GLN A 39 B 2 ILE A 45 ? ASP A 46 ? ILE A 45 ASP A 46 C 1 TRP A 113 ? ILE A 118 ? TRP A 113 ILE A 118 C 2 ARG A 121 ? GLU A 126 ? ARG A 121 GLU A 126 D 1 GLN B 2 ? GLN B 5 ? GLN U 2 GLN U 5 D 2 LEU B 13 ? GLU B 16 ? LEU U 13 GLU U 16 E 1 LEU B 38 ? CYS B 45 ? LEU U 38 CYS U 45 E 2 CYS B 24 ? TRP B 32 ? CYS U 24 TRP U 32 E 3 MET B 62 ? GLU B 68 ? MET U 62 GLU U 68 E 4 ARG B 53 ? MET B 59 ? ARG U 53 MET U 59 E 5 TYR B 141 ? SER B 147 ? TYR U 141 SER U 147 E 6 CYS B 99 ? THR B 100 ? CYS U 99 THR U 100 F 1 LEU B 38 ? CYS B 45 ? LEU U 38 CYS U 45 F 2 CYS B 24 ? TRP B 32 ? CYS U 24 TRP U 32 F 3 MET B 62 ? GLU B 68 ? MET U 62 GLU U 68 F 4 ARG B 53 ? MET B 59 ? ARG U 53 MET U 59 F 5 TYR B 141 ? SER B 147 ? TYR U 141 SER U 147 F 6 CYS B 123 ? GLN B 130 ? CYS U 123 GLN U 130 F 7 THR B 162 ? CYS B 169 ? THR U 162 CYS U 169 F 8 GLY B 153 ? HIS B 158 ? GLY U 153 HIS U 158 F 9 VAL B 236 ? ALA B 240 ? VAL U 236 ALA U 240 F 10 GLN B 219 ? ALA B 223 ? GLN U 219 ALA U 223 F 11 VAL B 262 ? CYS B 265 ? VAL U 262 CYS U 265 G 1 GLU B 95 ? ALA B 97 ? GLU U 95 ALA U 97 G 2 SER B 113 ? GLN B 115 ? SER U 113 GLN U 115 H 1 GLN B 191 ? SER B 194 ? GLN U 191 SER U 194 H 2 SER B 209 ? ASN B 212 ? SER U 209 ASN U 212 I 1 VAL C 19 ? CYS C 20 ? VAL B 19 CYS B 20 I 2 CYS C 32 ? SER C 33 ? CYS B 32 SER B 33 J 1 PHE C 38 ? GLN C 39 ? PHE B 38 GLN B 39 J 2 ILE C 45 ? ASP C 46 ? ILE B 45 ASP B 46 K 1 TRP C 113 ? VAL C 116 ? TRP B 113 VAL B 116 K 2 PHE C 123 ? GLU C 126 ? PHE B 123 GLU B 126 L 1 GLN D 2 ? GLN D 5 ? GLN V 2 GLN V 5 L 2 LEU D 13 ? GLU D 16 ? LEU V 13 GLU V 16 M 1 GLU D 39 ? CYS D 45 ? GLU V 39 CYS V 45 M 2 CYS D 24 ? ARG D 30 ? CYS V 24 ARG V 30 M 3 MET D 62 ? CYS D 71 ? MET V 62 CYS V 71 M 4 ARG D 53 ? MET D 59 ? ARG V 53 MET V 59 M 5 TYR D 141 ? SER D 147 ? TYR V 141 SER V 147 M 6 CYS D 99 ? THR D 100 ? CYS V 99 THR V 100 N 1 GLU D 39 ? CYS D 45 ? GLU V 39 CYS V 45 N 2 CYS D 24 ? ARG D 30 ? CYS V 24 ARG V 30 N 3 MET D 62 ? CYS D 71 ? MET V 62 CYS V 71 N 4 ARG D 53 ? MET D 59 ? ARG V 53 MET V 59 N 5 TYR D 141 ? SER D 147 ? TYR V 141 SER V 147 N 6 HIS D 122 ? LEU D 129 ? HIS V 122 LEU V 129 N 7 PHE D 163 ? CYS D 169 ? PHE V 163 CYS V 169 N 8 GLY D 153 ? HIS D 158 ? GLY V 153 HIS V 158 N 9 TYR D 234 ? ALA D 240 ? TYR V 234 ALA V 240 N 10 GLN D 219 ? GLY D 225 ? GLN V 219 GLY V 225 N 11 VAL D 262 ? CYS D 264 ? VAL V 262 CYS V 264 O 1 GLU D 95 ? CYS D 96 ? GLU V 95 CYS V 96 O 2 LEU D 114 ? GLN D 115 ? LEU V 114 GLN V 115 P 1 PRO D 187 ? TYR D 193 ? PRO V 187 TYR V 193 P 2 LEU D 210 ? ARG D 214 ? LEU V 210 ARG V 214 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 21 ? N VAL A 21 O ARG A 31 ? O ARG A 31 B 1 2 N GLN A 39 ? N GLN A 39 O ILE A 45 ? O ILE A 45 C 1 2 N VAL A 116 ? N VAL A 116 O PHE A 123 ? O PHE A 123 D 1 2 N GLN B 5 ? N GLN U 5 O LEU B 13 ? O LEU U 13 E 1 2 O VAL B 40 ? O VAL U 40 N LEU B 29 ? N LEU U 29 E 2 3 N VAL B 28 ? N VAL U 28 O THR B 67 ? O THR U 67 E 3 4 O GLU B 68 ? O GLU U 68 N ARG B 53 ? N ARG U 53 E 4 5 N SER B 56 ? N SER U 56 O CYS B 145 ? O CYS U 145 E 5 6 O ARG B 143 ? O ARG U 143 N CYS B 99 ? N CYS U 99 F 1 2 O VAL B 40 ? O VAL U 40 N LEU B 29 ? N LEU U 29 F 2 3 N VAL B 28 ? N VAL U 28 O THR B 67 ? O THR U 67 F 3 4 O GLU B 68 ? O GLU U 68 N ARG B 53 ? N ARG U 53 F 4 5 N SER B 56 ? N SER U 56 O CYS B 145 ? O CYS U 145 F 5 6 O THR B 142 ? O THR U 142 N VAL B 126 ? N VAL U 126 F 6 7 N VAL B 127 ? N VAL U 127 O PHE B 165 ? O PHE U 165 F 7 8 O LEU B 166 ? O LEU U 166 N ALA B 155 ? N ALA U 155 F 8 9 N HIS B 158 ? N HIS U 158 O CYS B 239 ? O CYS U 239 F 9 10 O GLY B 238 ? O GLY U 238 N LEU B 221 ? N LEU U 221 F 10 11 N CYS B 220 ? N CYS U 220 O CYS B 265 ? O CYS U 265 G 1 2 N CYS B 96 ? N CYS U 96 O LEU B 114 ? O LEU U 114 H 1 2 N CYS B 192 ? N CYS U 192 O ILE B 211 ? O ILE U 211 I 1 2 N VAL C 19 ? N VAL B 19 O SER C 33 ? O SER B 33 J 1 2 N GLN C 39 ? N GLN B 39 O ILE C 45 ? O ILE B 45 K 1 2 N CYS C 114 ? N CYS B 114 O GLN C 125 ? O GLN B 125 L 1 2 N CYS D 3 ? N CYS V 3 O GLU D 15 ? O GLU V 15 M 1 2 O THR D 42 ? O THR V 42 N THR D 27 ? N THR V 27 M 2 3 N CYS D 24 ? N CYS V 24 O CYS D 71 ? O CYS V 71 M 3 4 O ILE D 64 ? O ILE V 64 N TYR D 57 ? N TYR V 57 M 4 5 N THR D 54 ? N THR V 54 O SER D 147 ? O SER V 147 M 5 6 O ARG D 143 ? O ARG V 143 N CYS D 99 ? N CYS V 99 N 1 2 O THR D 42 ? O THR V 42 N THR D 27 ? N THR V 27 N 2 3 N CYS D 24 ? N CYS V 24 O CYS D 71 ? O CYS V 71 N 3 4 O ILE D 64 ? O ILE V 64 N TYR D 57 ? N TYR V 57 N 4 5 N THR D 54 ? N THR V 54 O SER D 147 ? O SER V 147 N 5 6 O GLY D 144 ? O GLY V 144 N ILE D 124 ? N ILE V 124 N 6 7 N CYS D 123 ? N CYS V 123 O CYS D 169 ? O CYS V 169 N 7 8 O HIS D 164 ? O HIS V 164 N PHE D 157 ? N PHE V 157 N 8 9 N HIS D 158 ? N HIS V 158 O CYS D 239 ? O CYS V 239 N 9 10 O ALA D 240 ? O ALA V 240 N GLN D 219 ? N GLN V 219 N 10 11 N VAL D 222 ? N VAL V 222 O SER D 263 ? O SER V 263 O 1 2 N CYS D 96 ? N CYS V 96 O LEU D 114 ? O LEU V 114 P 1 2 N CYS D 192 ? N CYS V 192 O ILE D 211 ? O ILE V 211 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG U 1052' AC2 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG U 1053' AC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG U 1160' AC4 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG U 1170' AC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG U 1259' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG V 1052' AC7 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG V 1053' AC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG V 1170' AC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG V 1160' BC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG V 1259' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 3 ASN B 52 ? ASN U 52 . ? 1_555 ? 2 AC1 3 VAL B 70 ? VAL U 70 . ? 1_555 ? 3 AC1 3 NAG F . ? NAG U 1053 . ? 1_555 ? 4 AC2 1 NAG E . ? NAG U 1052 . ? 1_555 ? 5 AC3 1 ASN B 160 ? ASN U 160 . ? 1_555 ? 6 AC4 1 ASN B 170 ? ASN U 170 . ? 1_555 ? 7 AC5 3 LEU B 19 ? LEU U 19 . ? 1_555 ? 8 AC5 3 LEU B 258 ? LEU U 258 . ? 1_555 ? 9 AC5 3 ASN B 259 ? ASN U 259 . ? 1_555 ? 10 AC6 3 ASN D 52 ? ASN V 52 . ? 1_555 ? 11 AC6 3 THR D 69 ? THR V 69 . ? 1_555 ? 12 AC6 3 NAG K . ? NAG V 1053 . ? 1_555 ? 13 AC7 1 NAG J . ? NAG V 1052 . ? 1_555 ? 14 AC8 3 HIS C 53 ? HIS B 53 . ? 1_655 ? 15 AC8 3 CYS C 132 ? CYS B 132 . ? 1_655 ? 16 AC8 3 ASN D 170 ? ASN V 170 . ? 1_555 ? 17 AC9 2 ASN D 160 ? ASN V 160 . ? 1_555 ? 18 AC9 2 GLN D 161 ? GLN V 161 . ? 1_555 ? 19 BC1 2 LEU D 258 ? LEU V 258 . ? 1_555 ? 20 BC1 2 ASN D 259 ? ASN V 259 . ? 1_555 ? # _database_PDB_matrix.entry_id 3LAQ _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3LAQ _atom_sites.fract_transf_matrix[1][1] 0.016281 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.004721 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.007286 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.015827 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLU A 1 9 ? 33.196 -6.265 27.411 1.00 70.31 ? 9 GLU A N 1 ATOM 2 C CA . GLU A 1 9 ? 32.936 -5.265 28.502 1.00 70.24 ? 9 GLU A CA 1 ATOM 3 C C . GLU A 1 9 ? 31.514 -4.612 28.467 1.00 69.62 ? 9 GLU A C 1 ATOM 4 O O . GLU A 1 9 ? 30.597 -5.070 27.745 1.00 69.29 ? 9 GLU A O 1 ATOM 5 C CB . GLU A 1 9 ? 34.067 -4.205 28.581 1.00 70.43 ? 9 GLU A CB 1 ATOM 6 C CG . GLU A 1 9 ? 35.445 -4.731 29.081 1.00 71.87 ? 9 GLU A CG 1 ATOM 7 C CD . GLU A 1 9 ? 36.395 -3.617 29.609 1.00 74.33 ? 9 GLU A CD 1 ATOM 8 O OE1 . GLU A 1 9 ? 35.905 -2.610 30.195 1.00 75.36 ? 9 GLU A OE1 1 ATOM 9 O OE2 . GLU A 1 9 ? 37.636 -3.760 29.454 1.00 73.97 ? 9 GLU A OE2 1 ATOM 10 N N . SER A 1 10 ? 31.359 -3.549 29.268 1.00 68.74 ? 10 SER A N 1 ATOM 11 C CA . SER A 1 10 ? 30.052 -3.007 29.668 1.00 67.40 ? 10 SER A CA 1 ATOM 12 C C . SER A 1 10 ? 29.995 -1.507 29.483 1.00 66.02 ? 10 SER A C 1 ATOM 13 O O . SER A 1 10 ? 29.265 -1.042 28.629 1.00 65.93 ? 10 SER A O 1 ATOM 14 C CB . SER A 1 10 ? 29.760 -3.330 31.140 1.00 67.47 ? 10 SER A CB 1 ATOM 15 O OG . SER A 1 10 ? 29.914 -4.717 31.402 1.00 68.74 ? 10 SER A OG 1 ATOM 16 N N . ASN A 1 11 ? 30.758 -0.773 30.300 1.00 63.89 ? 11 ASN A N 1 ATOM 17 C CA . ASN A 1 11 ? 30.815 0.697 30.288 1.00 61.97 ? 11 ASN A CA 1 ATOM 18 C C . ASN A 1 11 ? 29.881 1.374 29.284 1.00 60.94 ? 11 ASN A C 1 ATOM 19 O O . ASN A 1 11 ? 30.332 2.075 28.369 1.00 60.90 ? 11 ASN A O 1 ATOM 20 C CB . ASN A 1 11 ? 32.260 1.193 30.115 1.00 61.86 ? 11 ASN A CB 1 ATOM 21 C CG . ASN A 1 11 ? 33.070 0.337 29.154 1.00 61.12 ? 11 ASN A CG 1 ATOM 22 O OD1 . ASN A 1 11 ? 34.179 -0.081 29.479 1.00 60.88 ? 11 ASN A OD1 1 ATOM 23 N ND2 . ASN A 1 11 ? 32.518 0.063 27.976 1.00 59.22 ? 11 ASN A ND2 1 ATOM 24 N N . CYS A 1 12 ? 28.580 1.133 29.466 1.00 59.38 ? 12 CYS A N 1 ATOM 25 C CA . CYS A 1 12 ? 27.507 1.749 28.685 1.00 57.79 ? 12 CYS A CA 1 ATOM 26 C C . CYS A 1 12 ? 26.313 1.957 29.600 1.00 57.13 ? 12 CYS A C 1 ATOM 27 O O . CYS A 1 12 ? 25.300 2.515 29.187 1.00 57.38 ? 12 CYS A O 1 ATOM 28 C CB . CYS A 1 12 ? 27.072 0.845 27.529 1.00 57.42 ? 12 CYS A CB 1 ATOM 29 S SG . CYS A 1 12 ? 28.213 0.725 26.100 1.00 57.03 ? 12 CYS A SG 1 ATOM 30 N N . GLY A 1 13 ? 26.443 1.512 30.849 1.00 56.25 ? 13 GLY A N 1 ATOM 31 C CA . GLY A 1 13 ? 25.325 1.455 31.804 1.00 54.84 ? 13 GLY A CA 1 ATOM 32 C C . GLY A 1 13 ? 24.936 0.011 32.083 1.00 53.73 ? 13 GLY A C 1 ATOM 33 O O . GLY A 1 13 ? 23.898 -0.275 32.680 1.00 53.71 ? 13 GLY A O 1 ATOM 34 N N . CYS A 1 14 ? 25.800 -0.898 31.657 1.00 52.43 ? 14 CYS A N 1 ATOM 35 C CA . CYS A 1 14 ? 25.509 -2.305 31.686 1.00 51.14 ? 14 CYS A CA 1 ATOM 36 C C . CYS A 1 14 ? 25.798 -2.916 33.034 1.00 50.31 ? 14 CYS A C 1 ATOM 37 O O . CYS A 1 14 ? 26.887 -3.433 33.314 1.00 49.89 ? 14 CYS A O 1 ATOM 38 C CB . CYS A 1 14 ? 26.244 -3.007 30.559 1.00 51.24 ? 14 CYS A CB 1 ATOM 39 S SG . CYS A 1 14 ? 25.264 -2.936 29.067 1.00 51.73 ? 14 CYS A SG 1 ATOM 40 N N . GLN A 1 15 ? 24.785 -2.835 33.880 1.00 49.40 ? 15 GLN A N 1 ATOM 41 C CA . GLN A 1 15 ? 24.862 -3.409 35.197 1.00 48.45 ? 15 GLN A CA 1 ATOM 42 C C . GLN A 1 15 ? 25.035 -4.936 35.109 1.00 47.66 ? 15 GLN A C 1 ATOM 43 O O . GLN A 1 15 ? 24.757 -5.551 34.058 1.00 47.67 ? 15 GLN A O 1 ATOM 44 C CB . GLN A 1 15 ? 23.651 -2.978 36.041 1.00 48.44 ? 15 GLN A CB 1 ATOM 45 C CG . GLN A 1 15 ? 23.837 -1.645 36.799 1.00 49.34 ? 15 GLN A CG 1 ATOM 46 C CD . GLN A 1 15 ? 24.777 -1.764 38.032 1.00 51.89 ? 15 GLN A CD 1 ATOM 47 O OE1 . GLN A 1 15 ? 26.010 -1.790 37.899 1.00 51.82 ? 15 GLN A OE1 1 ATOM 48 N NE2 . GLN A 1 15 ? 24.185 -1.826 39.234 1.00 52.25 ? 15 GLN A NE2 1 ATOM 49 N N . ASN A 1 16 ? 25.533 -5.513 36.212 1.00 46.45 ? 16 ASN A N 1 ATOM 50 C CA . ASN A 1 16 ? 25.805 -6.948 36.376 1.00 44.71 ? 16 ASN A CA 1 ATOM 51 C C . ASN A 1 16 ? 26.734 -7.542 35.316 1.00 44.31 ? 16 ASN A C 1 ATOM 52 O O . ASN A 1 16 ? 27.795 -6.978 35.017 1.00 44.26 ? 16 ASN A O 1 ATOM 53 C CB . ASN A 1 16 ? 24.498 -7.727 36.520 1.00 44.14 ? 16 ASN A CB 1 ATOM 54 C CG . ASN A 1 16 ? 23.732 -7.329 37.768 1.00 42.72 ? 16 ASN A CG 1 ATOM 55 O OD1 . ASN A 1 16 ? 23.887 -7.949 38.807 1.00 42.30 ? 16 ASN A OD1 1 ATOM 56 N ND2 . ASN A 1 16 ? 22.937 -6.270 37.682 1.00 39.96 ? 16 ASN A ND2 1 ATOM 57 N N . GLY A 1 17 ? 26.348 -8.679 34.758 1.00 43.74 ? 17 GLY A N 1 ATOM 58 C CA . GLY A 1 17 ? 27.130 -9.277 33.687 1.00 43.45 ? 17 GLY A CA 1 ATOM 59 C C . GLY A 1 17 ? 26.783 -8.719 32.314 1.00 43.16 ? 17 GLY A C 1 ATOM 60 O O . GLY A 1 17 ? 27.084 -9.351 31.304 1.00 43.11 ? 17 GLY A O 1 ATOM 61 N N . GLY A 1 18 ? 26.152 -7.542 32.282 1.00 42.78 ? 18 GLY A N 1 ATOM 62 C CA . GLY A 1 18 ? 25.754 -6.885 31.045 1.00 42.40 ? 18 GLY A CA 1 ATOM 63 C C . GLY A 1 18 ? 26.884 -6.760 30.044 1.00 42.47 ? 18 GLY A C 1 ATOM 64 O O . GLY A 1 18 ? 28.012 -6.447 30.411 1.00 42.06 ? 18 GLY A O 1 ATOM 65 N N . VAL A 1 19 ? 26.583 -7.031 28.774 1.00 42.89 ? 19 VAL A N 1 ATOM 66 C CA . VAL A 1 19 ? 27.561 -6.843 27.688 1.00 43.25 ? 19 VAL A CA 1 ATOM 67 C C . VAL A 1 19 ? 27.114 -5.743 26.714 1.00 43.45 ? 19 VAL A C 1 ATOM 68 O O . VAL A 1 19 ? 25.982 -5.747 26.211 1.00 43.08 ? 19 VAL A O 1 ATOM 69 C CB . VAL A 1 19 ? 27.904 -8.166 26.944 1.00 43.08 ? 19 VAL A CB 1 ATOM 70 C CG1 . VAL A 1 19 ? 28.452 -7.892 25.556 1.00 42.76 ? 19 VAL A CG1 1 ATOM 71 C CG2 . VAL A 1 19 ? 28.901 -8.976 27.744 1.00 43.03 ? 19 VAL A CG2 1 ATOM 72 N N . CYS A 1 20 ? 28.012 -4.793 26.474 1.00 43.61 ? 20 CYS A N 1 ATOM 73 C CA . CYS A 1 20 ? 27.674 -3.691 25.616 1.00 43.82 ? 20 CYS A CA 1 ATOM 74 C C . CYS A 1 20 ? 27.939 -4.063 24.183 1.00 42.37 ? 20 CYS A C 1 ATOM 75 O O . CYS A 1 20 ? 29.088 -4.281 23.792 1.00 41.90 ? 20 CYS A O 1 ATOM 76 C CB . CYS A 1 20 ? 28.428 -2.417 25.990 1.00 44.69 ? 20 CYS A CB 1 ATOM 77 S SG . CYS A 1 20 ? 27.659 -1.012 25.143 1.00 50.50 ? 20 CYS A SG 1 ATOM 78 N N . VAL A 1 21 ? 26.849 -4.141 23.421 1.00 41.26 ? 21 VAL A N 1 ATOM 79 C CA . VAL A 1 21 ? 26.889 -4.310 21.964 1.00 39.96 ? 21 VAL A CA 1 ATOM 80 C C . VAL A 1 21 ? 26.209 -3.112 21.288 1.00 39.10 ? 21 VAL A C 1 ATOM 81 O O . VAL A 1 21 ? 25.094 -2.743 21.649 1.00 38.91 ? 21 VAL A O 1 ATOM 82 C CB . VAL A 1 21 ? 26.252 -5.664 21.520 1.00 40.05 ? 21 VAL A CB 1 ATOM 83 C CG1 . VAL A 1 21 ? 26.136 -6.638 22.711 1.00 39.82 ? 21 VAL A CG1 1 ATOM 84 C CG2 . VAL A 1 21 ? 24.891 -5.475 20.875 1.00 39.85 ? 21 VAL A CG2 1 ATOM 85 N N . SER A 1 22 ? 26.895 -2.490 20.335 1.00 38.33 ? 22 SER A N 1 ATOM 86 C CA . SER A 1 22 ? 26.347 -1.326 19.609 1.00 37.92 ? 22 SER A CA 1 ATOM 87 C C . SER A 1 22 ? 25.917 -1.677 18.171 1.00 37.00 ? 22 SER A C 1 ATOM 88 O O . SER A 1 22 ? 25.855 -2.846 17.816 1.00 37.24 ? 22 SER A O 1 ATOM 89 C CB . SER A 1 22 ? 27.350 -0.163 19.608 1.00 38.38 ? 22 SER A CB 1 ATOM 90 O OG . SER A 1 22 ? 28.240 -0.213 18.493 1.00 38.67 ? 22 SER A OG 1 ATOM 91 N N . TYR A 1 23 ? 25.648 -0.680 17.334 1.00 35.72 ? 23 TYR A N 1 ATOM 92 C CA . TYR A 1 23 ? 25.077 -0.956 16.016 1.00 34.57 ? 23 TYR A CA 1 ATOM 93 C C . TYR A 1 23 ? 25.347 0.098 14.950 1.00 33.25 ? 23 TYR A C 1 ATOM 94 O O . TYR A 1 23 ? 24.572 1.042 14.802 1.00 32.87 ? 23 TYR A O 1 ATOM 95 C CB . TYR A 1 23 ? 23.578 -1.151 16.159 1.00 34.84 ? 23 TYR A CB 1 ATOM 96 C CG . TYR A 1 23 ? 23.195 -2.487 16.720 1.00 36.42 ? 23 TYR A CG 1 ATOM 97 C CD1 . TYR A 1 23 ? 23.438 -3.653 16.008 1.00 37.62 ? 23 TYR A CD1 1 ATOM 98 C CD2 . TYR A 1 23 ? 22.581 -2.590 17.973 1.00 38.92 ? 23 TYR A CD2 1 ATOM 99 C CE1 . TYR A 1 23 ? 23.079 -4.903 16.531 1.00 40.17 ? 23 TYR A CE1 1 ATOM 100 C CE2 . TYR A 1 23 ? 22.202 -3.837 18.504 1.00 40.16 ? 23 TYR A CE2 1 ATOM 101 C CZ . TYR A 1 23 ? 22.459 -4.990 17.774 1.00 40.46 ? 23 TYR A CZ 1 ATOM 102 O OH . TYR A 1 23 ? 22.104 -6.226 18.271 1.00 40.62 ? 23 TYR A OH 1 ATOM 103 N N . LYS A 1 24 ? 26.406 -0.096 14.172 1.00 31.92 ? 24 LYS A N 1 ATOM 104 C CA . LYS A 1 24 ? 26.921 0.987 13.340 1.00 31.26 ? 24 LYS A CA 1 ATOM 105 C C . LYS A 1 24 ? 25.910 1.680 12.430 1.00 30.89 ? 24 LYS A C 1 ATOM 106 O O . LYS A 1 24 ? 25.766 2.897 12.505 1.00 31.18 ? 24 LYS A O 1 ATOM 107 C CB . LYS A 1 24 ? 28.216 0.627 12.597 1.00 31.12 ? 24 LYS A CB 1 ATOM 108 C CG . LYS A 1 24 ? 28.159 -0.513 11.613 1.00 30.83 ? 24 LYS A CG 1 ATOM 109 C CD . LYS A 1 24 ? 29.504 -1.220 11.624 1.00 30.94 ? 24 LYS A CD 1 ATOM 110 C CE . LYS A 1 24 ? 29.828 -1.841 10.293 1.00 31.65 ? 24 LYS A CE 1 ATOM 111 N NZ . LYS A 1 24 ? 28.863 -2.890 9.869 1.00 31.30 ? 24 LYS A NZ 1 ATOM 112 N N . TYR A 1 25 ? 25.201 0.919 11.603 1.00 30.12 ? 25 TYR A N 1 ATOM 113 C CA . TYR A 1 25 ? 24.259 1.507 10.655 1.00 29.34 ? 25 TYR A CA 1 ATOM 114 C C . TYR A 1 25 ? 23.082 2.171 11.354 1.00 29.55 ? 25 TYR A C 1 ATOM 115 O O . TYR A 1 25 ? 22.383 3.003 10.786 1.00 29.48 ? 25 TYR A O 1 ATOM 116 C CB . TYR A 1 25 ? 23.751 0.454 9.666 1.00 29.18 ? 25 TYR A CB 1 ATOM 117 C CG . TYR A 1 25 ? 24.831 -0.163 8.819 1.00 26.82 ? 25 TYR A CG 1 ATOM 118 C CD1 . TYR A 1 25 ? 25.609 0.619 7.969 1.00 25.39 ? 25 TYR A CD1 1 ATOM 119 C CD2 . TYR A 1 25 ? 25.071 -1.519 8.863 1.00 24.86 ? 25 TYR A CD2 1 ATOM 120 C CE1 . TYR A 1 25 ? 26.605 0.067 7.187 1.00 24.56 ? 25 TYR A CE1 1 ATOM 121 C CE2 . TYR A 1 25 ? 26.072 -2.087 8.094 1.00 25.16 ? 25 TYR A CE2 1 ATOM 122 C CZ . TYR A 1 25 ? 26.838 -1.290 7.253 1.00 24.83 ? 25 TYR A CZ 1 ATOM 123 O OH . TYR A 1 25 ? 27.829 -1.858 6.479 1.00 23.87 ? 25 TYR A OH 1 ATOM 124 N N . PHE A 1 26 ? 22.857 1.801 12.598 1.00 29.79 ? 26 PHE A N 1 ATOM 125 C CA . PHE A 1 26 ? 21.774 2.418 13.329 1.00 30.24 ? 26 PHE A CA 1 ATOM 126 C C . PHE A 1 26 ? 22.280 3.366 14.400 1.00 30.43 ? 26 PHE A C 1 ATOM 127 O O . PHE A 1 26 ? 21.953 3.230 15.569 1.00 30.64 ? 26 PHE A O 1 ATOM 128 C CB . PHE A 1 26 ? 20.840 1.361 13.890 1.00 30.09 ? 26 PHE A CB 1 ATOM 129 C CG . PHE A 1 26 ? 20.178 0.562 12.840 1.00 29.94 ? 26 PHE A CG 1 ATOM 130 C CD1 . PHE A 1 26 ? 20.923 -0.261 12.004 1.00 29.07 ? 26 PHE A CD1 1 ATOM 131 C CD2 . PHE A 1 26 ? 18.809 0.642 12.661 1.00 31.33 ? 26 PHE A CD2 1 ATOM 132 C CE1 . PHE A 1 26 ? 20.319 -1.002 11.024 1.00 28.62 ? 26 PHE A CE1 1 ATOM 133 C CE2 . PHE A 1 26 ? 18.186 -0.113 11.664 1.00 31.12 ? 26 PHE A CE2 1 ATOM 134 C CZ . PHE A 1 26 ? 18.950 -0.936 10.852 1.00 29.70 ? 26 PHE A CZ 1 ATOM 135 N N . SER A 1 27 ? 23.087 4.327 13.969 1.00 30.56 ? 27 SER A N 1 ATOM 136 C CA . SER A 1 27 ? 23.526 5.439 14.808 1.00 30.57 ? 27 SER A CA 1 ATOM 137 C C . SER A 1 27 ? 24.101 5.086 16.215 1.00 30.83 ? 27 SER A C 1 ATOM 138 O O . SER A 1 27 ? 23.733 5.683 17.219 1.00 30.44 ? 27 SER A O 1 ATOM 139 C CB . SER A 1 27 ? 22.433 6.525 14.853 1.00 30.43 ? 27 SER A CB 1 ATOM 140 O OG . SER A 1 27 ? 21.153 5.991 14.573 1.00 28.60 ? 27 SER A OG 1 ATOM 141 N N . ARG A 1 28 ? 25.029 4.127 16.240 1.00 31.48 ? 28 ARG A N 1 ATOM 142 C CA . ARG A 1 28 ? 25.738 3.659 17.442 1.00 32.64 ? 28 ARG A CA 1 ATOM 143 C C . ARG A 1 28 ? 24.835 3.438 18.659 1.00 32.73 ? 28 ARG A C 1 ATOM 144 O O . ARG A 1 28 ? 25.320 3.397 19.786 1.00 32.78 ? 28 ARG A O 1 ATOM 145 C CB . ARG A 1 28 ? 26.923 4.560 17.799 1.00 32.88 ? 28 ARG A CB 1 ATOM 146 C CG . ARG A 1 28 ? 27.547 5.280 16.619 1.00 37.31 ? 28 ARG A CG 1 ATOM 147 C CD . ARG A 1 28 ? 28.600 4.460 15.825 1.00 45.74 ? 28 ARG A CD 1 ATOM 148 N NE . ARG A 1 28 ? 28.716 3.035 16.209 1.00 50.75 ? 28 ARG A NE 1 ATOM 149 C CZ . ARG A 1 28 ? 29.656 2.187 15.750 1.00 52.40 ? 28 ARG A CZ 1 ATOM 150 N NH1 . ARG A 1 28 ? 30.577 2.592 14.861 1.00 51.19 ? 28 ARG A NH1 1 ATOM 151 N NH2 . ARG A 1 28 ? 29.675 0.922 16.184 1.00 52.67 ? 28 ARG A NH2 1 ATOM 152 N N . ILE A 1 29 ? 23.527 3.308 18.412 1.00 33.13 ? 29 ILE A N 1 ATOM 153 C CA . ILE A 1 29 ? 22.550 2.834 19.393 1.00 33.39 ? 29 ILE A CA 1 ATOM 154 C C . ILE A 1 29 ? 23.087 1.566 20.039 1.00 34.69 ? 29 ILE A C 1 ATOM 155 O O . ILE A 1 29 ? 23.762 0.764 19.384 1.00 34.84 ? 29 ILE A O 1 ATOM 156 C CB . ILE A 1 29 ? 21.151 2.581 18.755 1.00 32.90 ? 29 ILE A CB 1 ATOM 157 C CG1 . ILE A 1 29 ? 20.080 2.452 19.818 1.00 31.94 ? 29 ILE A CG1 1 ATOM 158 C CG2 . ILE A 1 29 ? 21.131 1.344 17.895 1.00 31.96 ? 29 ILE A CG2 1 ATOM 159 C CD1 . ILE A 1 29 ? 18.704 2.685 19.284 1.00 31.32 ? 29 ILE A CD1 1 ATOM 160 N N . ARG A 1 30 ? 22.823 1.409 21.333 1.00 35.98 ? 30 ARG A N 1 ATOM 161 C CA . ARG A 1 30 ? 23.403 0.317 22.094 1.00 37.42 ? 30 ARG A CA 1 ATOM 162 C C . ARG A 1 30 ? 22.285 -0.472 22.699 1.00 37.95 ? 30 ARG A C 1 ATOM 163 O O . ARG A 1 30 ? 21.207 0.067 22.899 1.00 38.52 ? 30 ARG A O 1 ATOM 164 C CB . ARG A 1 30 ? 24.311 0.827 23.218 1.00 37.53 ? 30 ARG A CB 1 ATOM 165 C CG . ARG A 1 30 ? 25.443 1.739 22.778 1.00 39.54 ? 30 ARG A CG 1 ATOM 166 C CD . ARG A 1 30 ? 25.087 3.211 23.028 1.00 43.65 ? 30 ARG A CD 1 ATOM 167 N NE . ARG A 1 30 ? 25.028 3.520 24.454 1.00 46.13 ? 30 ARG A NE 1 ATOM 168 C CZ . ARG A 1 30 ? 26.033 4.046 25.147 1.00 47.89 ? 30 ARG A CZ 1 ATOM 169 N NH1 . ARG A 1 30 ? 27.190 4.341 24.543 1.00 47.74 ? 30 ARG A NH1 1 ATOM 170 N NH2 . ARG A 1 30 ? 25.877 4.283 26.448 1.00 49.04 ? 30 ARG A NH2 1 ATOM 171 N N . ARG A 1 31 ? 22.532 -1.753 22.964 1.00 38.64 ? 31 ARG A N 1 ATOM 172 C CA . ARG A 1 31 ? 21.665 -2.532 23.827 1.00 39.07 ? 31 ARG A CA 1 ATOM 173 C C . ARG A 1 31 ? 22.582 -3.392 24.644 1.00 39.35 ? 31 ARG A C 1 ATOM 174 O O . ARG A 1 31 ? 23.730 -3.639 24.259 1.00 38.93 ? 31 ARG A O 1 ATOM 175 C CB . ARG A 1 31 ? 20.653 -3.361 23.023 1.00 39.23 ? 31 ARG A CB 1 ATOM 176 C CG . ARG A 1 31 ? 20.817 -4.855 23.104 1.00 39.84 ? 31 ARG A CG 1 ATOM 177 C CD . ARG A 1 31 ? 20.351 -5.546 21.832 1.00 41.32 ? 31 ARG A CD 1 ATOM 178 N NE . ARG A 1 31 ? 20.214 -6.997 22.023 1.00 41.62 ? 31 ARG A NE 1 ATOM 179 C CZ . ARG A 1 31 ? 21.202 -7.879 21.910 1.00 40.23 ? 31 ARG A CZ 1 ATOM 180 N NH1 . ARG A 1 31 ? 22.431 -7.485 21.604 1.00 39.08 ? 31 ARG A NH1 1 ATOM 181 N NH2 . ARG A 1 31 ? 20.956 -9.159 22.117 1.00 40.03 ? 31 ARG A NH2 1 ATOM 182 N N . CYS A 1 32 ? 22.068 -3.817 25.788 1.00 40.12 ? 32 CYS A N 1 ATOM 183 C CA . CYS A 1 32 ? 22.811 -4.623 26.738 1.00 41.39 ? 32 CYS A CA 1 ATOM 184 C C . CYS A 1 32 ? 22.452 -6.115 26.540 1.00 40.48 ? 32 CYS A C 1 ATOM 185 O O . CYS A 1 32 ? 21.294 -6.446 26.304 1.00 40.86 ? 32 CYS A O 1 ATOM 186 C CB . CYS A 1 32 ? 22.493 -4.115 28.158 1.00 42.03 ? 32 CYS A CB 1 ATOM 187 S SG . CYS A 1 32 ? 23.819 -4.330 29.451 1.00 48.83 ? 32 CYS A SG 1 ATOM 188 N N . SER A 1 33 ? 23.435 -7.015 26.599 1.00 39.48 ? 33 SER A N 1 ATOM 189 C CA . SER A 1 33 ? 23.142 -8.446 26.441 1.00 38.22 ? 33 SER A CA 1 ATOM 190 C C . SER A 1 33 ? 23.160 -9.134 27.791 1.00 36.84 ? 33 SER A C 1 ATOM 191 O O . SER A 1 33 ? 24.214 -9.491 28.288 1.00 36.16 ? 33 SER A O 1 ATOM 192 C CB . SER A 1 33 ? 24.143 -9.120 25.501 1.00 38.76 ? 33 SER A CB 1 ATOM 193 O OG . SER A 1 33 ? 25.332 -9.467 26.202 1.00 39.69 ? 33 SER A OG 1 ATOM 194 N N . CYS A 1 34 ? 21.982 -9.328 28.364 1.00 35.77 ? 34 CYS A N 1 ATOM 195 C CA . CYS A 1 34 ? 21.868 -9.723 29.762 1.00 35.19 ? 34 CYS A CA 1 ATOM 196 C C . CYS A 1 34 ? 22.066 -11.223 30.023 1.00 34.78 ? 34 CYS A C 1 ATOM 197 O O . CYS A 1 34 ? 21.804 -12.056 29.139 1.00 35.24 ? 34 CYS A O 1 ATOM 198 C CB . CYS A 1 34 ? 20.531 -9.247 30.340 1.00 34.94 ? 34 CYS A CB 1 ATOM 199 S SG . CYS A 1 34 ? 20.274 -7.430 30.373 1.00 35.03 ? 34 CYS A SG 1 ATOM 200 N N . PRO A 1 35 ? 22.554 -11.572 31.232 1.00 33.84 ? 35 PRO A N 1 ATOM 201 C CA . PRO A 1 35 ? 22.533 -12.942 31.703 1.00 33.13 ? 35 PRO A CA 1 ATOM 202 C C . PRO A 1 35 ? 21.149 -13.262 32.224 1.00 32.74 ? 35 PRO A C 1 ATOM 203 O O . PRO A 1 35 ? 20.316 -12.365 32.338 1.00 32.49 ? 35 PRO A O 1 ATOM 204 C CB . PRO A 1 35 ? 23.530 -12.925 32.851 1.00 32.96 ? 35 PRO A CB 1 ATOM 205 C CG . PRO A 1 35 ? 24.322 -11.710 32.643 1.00 33.28 ? 35 PRO A CG 1 ATOM 206 C CD . PRO A 1 35 ? 23.369 -10.733 32.115 1.00 33.58 ? 35 PRO A CD 1 ATOM 207 N N . ARG A 1 36 ? 20.905 -14.529 32.551 1.00 32.57 ? 36 ARG A N 1 ATOM 208 C CA . ARG A 1 36 ? 19.537 -14.983 32.824 1.00 32.06 ? 36 ARG A CA 1 ATOM 209 C C . ARG A 1 36 ? 18.884 -14.254 33.978 1.00 30.95 ? 36 ARG A C 1 ATOM 210 O O . ARG A 1 36 ? 17.703 -13.927 33.893 1.00 30.62 ? 36 ARG A O 1 ATOM 211 C CB . ARG A 1 36 ? 19.404 -16.529 32.951 1.00 32.62 ? 36 ARG A CB 1 ATOM 212 C CG . ARG A 1 36 ? 19.915 -17.210 34.237 1.00 34.28 ? 36 ARG A CG 1 ATOM 213 C CD . ARG A 1 36 ? 19.190 -18.593 34.501 1.00 36.84 ? 36 ARG A CD 1 ATOM 214 N NE . ARG A 1 36 ? 20.110 -19.691 34.906 1.00 38.13 ? 36 ARG A NE 1 ATOM 215 C CZ . ARG A 1 36 ? 20.205 -20.237 36.127 1.00 37.60 ? 36 ARG A CZ 1 ATOM 216 N NH1 . ARG A 1 36 ? 19.434 -19.829 37.125 1.00 35.67 ? 36 ARG A NH1 1 ATOM 217 N NH2 . ARG A 1 36 ? 21.072 -21.222 36.345 1.00 38.21 ? 36 ARG A NH2 1 ATOM 218 N N . LYS A 1 37 ? 19.669 -13.971 35.019 1.00 29.92 ? 37 LYS A N 1 ATOM 219 C CA . LYS A 1 37 ? 19.156 -13.366 36.261 1.00 28.87 ? 37 LYS A CA 1 ATOM 220 C C . LYS A 1 37 ? 18.628 -11.936 36.097 1.00 27.55 ? 37 LYS A C 1 ATOM 221 O O . LYS A 1 37 ? 17.621 -11.568 36.701 1.00 26.45 ? 37 LYS A O 1 ATOM 222 C CB . LYS A 1 37 ? 20.224 -13.418 37.364 1.00 29.16 ? 37 LYS A CB 1 ATOM 223 C CG . LYS A 1 37 ? 19.663 -13.713 38.761 1.00 30.37 ? 37 LYS A CG 1 ATOM 224 C CD . LYS A 1 37 ? 20.555 -13.186 39.922 1.00 33.12 ? 37 LYS A CD 1 ATOM 225 C CE . LYS A 1 37 ? 21.902 -13.945 40.111 1.00 33.75 ? 37 LYS A CE 1 ATOM 226 N NZ . LYS A 1 37 ? 21.790 -15.346 40.643 1.00 32.46 ? 37 LYS A NZ 1 ATOM 227 N N . PHE A 1 38 ? 19.295 -11.153 35.254 1.00 26.78 ? 38 PHE A N 1 ATOM 228 C CA . PHE A 1 38 ? 19.019 -9.725 35.153 1.00 26.50 ? 38 PHE A CA 1 ATOM 229 C C . PHE A 1 38 ? 18.409 -9.279 33.846 1.00 26.31 ? 38 PHE A C 1 ATOM 230 O O . PHE A 1 38 ? 19.072 -9.207 32.825 1.00 26.61 ? 38 PHE A O 1 ATOM 231 C CB . PHE A 1 38 ? 20.273 -8.923 35.471 1.00 26.48 ? 38 PHE A CB 1 ATOM 232 C CG . PHE A 1 38 ? 20.883 -9.298 36.789 1.00 27.57 ? 38 PHE A CG 1 ATOM 233 C CD1 . PHE A 1 38 ? 20.417 -8.723 37.976 1.00 26.01 ? 38 PHE A CD1 1 ATOM 234 C CD2 . PHE A 1 38 ? 21.893 -10.273 36.855 1.00 28.16 ? 38 PHE A CD2 1 ATOM 235 C CE1 . PHE A 1 38 ? 20.942 -9.095 39.183 1.00 24.52 ? 38 PHE A CE1 1 ATOM 236 C CE2 . PHE A 1 38 ? 22.434 -10.647 38.074 1.00 26.49 ? 38 PHE A CE2 1 ATOM 237 C CZ . PHE A 1 38 ? 21.950 -10.056 39.236 1.00 26.04 ? 38 PHE A CZ 1 ATOM 238 N N . GLN A 1 39 ? 17.127 -8.970 33.896 1.00 26.07 ? 39 GLN A N 1 ATOM 239 C CA . GLN A 1 39 ? 16.401 -8.534 32.734 1.00 26.17 ? 39 GLN A CA 1 ATOM 240 C C . GLN A 1 39 ? 16.533 -7.040 32.600 1.00 26.94 ? 39 GLN A C 1 ATOM 241 O O . GLN A 1 39 ? 17.247 -6.416 33.392 1.00 27.57 ? 39 GLN A O 1 ATOM 242 C CB . GLN A 1 39 ? 14.961 -8.935 32.889 1.00 25.55 ? 39 GLN A CB 1 ATOM 243 C CG . GLN A 1 39 ? 14.825 -10.430 33.095 1.00 25.05 ? 39 GLN A CG 1 ATOM 244 C CD . GLN A 1 39 ? 13.391 -10.826 33.251 1.00 25.41 ? 39 GLN A CD 1 ATOM 245 O OE1 . GLN A 1 39 ? 13.032 -12.004 33.162 1.00 23.87 ? 39 GLN A OE1 1 ATOM 246 N NE2 . GLN A 1 39 ? 12.539 -9.826 33.472 1.00 26.68 ? 39 GLN A NE2 1 ATOM 247 N N . GLY A 1 40 ? 15.881 -6.455 31.597 1.00 27.38 ? 40 GLY A N 1 ATOM 248 C CA . GLY A 1 40 ? 15.820 -4.986 31.507 1.00 28.07 ? 40 GLY A CA 1 ATOM 249 C C . GLY A 1 40 ? 17.006 -4.311 30.838 1.00 28.54 ? 40 GLY A C 1 ATOM 250 O O . GLY A 1 40 ? 18.083 -4.898 30.721 1.00 28.92 ? 40 GLY A O 1 ATOM 251 N N . GLU A 1 41 ? 16.796 -3.060 30.427 1.00 28.73 ? 41 GLU A N 1 ATOM 252 C CA . GLU A 1 41 ? 17.637 -2.353 29.454 1.00 28.92 ? 41 GLU A CA 1 ATOM 253 C C . GLU A 1 41 ? 19.035 -2.068 29.934 1.00 29.05 ? 41 GLU A C 1 ATOM 254 O O . GLU A 1 41 ? 19.820 -1.475 29.223 1.00 29.31 ? 41 GLU A O 1 ATOM 255 C CB . GLU A 1 41 ? 16.949 -1.049 29.068 1.00 29.05 ? 41 GLU A CB 1 ATOM 256 C CG . GLU A 1 41 ? 17.781 -0.046 28.293 1.00 30.72 ? 41 GLU A CG 1 ATOM 257 C CD . GLU A 1 41 ? 17.154 1.359 28.272 1.00 34.16 ? 41 GLU A CD 1 ATOM 258 O OE1 . GLU A 1 41 ? 17.917 2.346 28.085 1.00 35.35 ? 41 GLU A OE1 1 ATOM 259 O OE2 . GLU A 1 41 ? 15.909 1.481 28.451 1.00 35.16 ? 41 GLU A OE2 1 ATOM 260 N N . HIS A 1 42 ? 19.355 -2.470 31.147 1.00 29.62 ? 42 HIS A N 1 ATOM 261 C CA . HIS A 1 42 ? 20.710 -2.301 31.629 1.00 30.57 ? 42 HIS A CA 1 ATOM 262 C C . HIS A 1 42 ? 21.160 -3.528 32.391 1.00 30.61 ? 42 HIS A C 1 ATOM 263 O O . HIS A 1 42 ? 22.306 -3.620 32.853 1.00 30.89 ? 42 HIS A O 1 ATOM 264 C CB . HIS A 1 42 ? 20.797 -1.060 32.498 1.00 30.86 ? 42 HIS A CB 1 ATOM 265 C CG . HIS A 1 42 ? 20.418 0.195 31.778 1.00 33.20 ? 42 HIS A CG 1 ATOM 266 N ND1 . HIS A 1 42 ? 19.227 0.856 32.007 1.00 34.89 ? 42 HIS A ND1 1 ATOM 267 C CD2 . HIS A 1 42 ? 21.059 0.896 30.811 1.00 34.88 ? 42 HIS A CD2 1 ATOM 268 C CE1 . HIS A 1 42 ? 19.162 1.925 31.233 1.00 35.75 ? 42 HIS A CE1 1 ATOM 269 N NE2 . HIS A 1 42 ? 20.257 1.967 30.491 1.00 36.42 ? 42 HIS A NE2 1 ATOM 270 N N . CYS A 1 43 ? 20.253 -4.495 32.474 1.00 30.47 ? 43 CYS A N 1 ATOM 271 C CA . CYS A 1 43 ? 20.451 -5.646 33.313 1.00 30.27 ? 43 CYS A CA 1 ATOM 272 C C . CYS A 1 43 ? 20.410 -5.011 34.675 1.00 29.13 ? 43 CYS A C 1 ATOM 273 O O . CYS A 1 43 ? 21.314 -5.117 35.471 1.00 29.27 ? 43 CYS A O 1 ATOM 274 C CB . CYS A 1 43 ? 21.774 -6.334 32.975 1.00 30.66 ? 43 CYS A CB 1 ATOM 275 S SG . CYS A 1 43 ? 22.019 -6.609 31.135 1.00 34.68 ? 43 CYS A SG 1 ATOM 276 N N . GLU A 1 44 ? 19.315 -4.309 34.888 1.00 28.11 ? 44 GLU A N 1 ATOM 277 C CA . GLU A 1 44 ? 19.097 -3.491 36.040 1.00 27.40 ? 44 GLU A CA 1 ATOM 278 C C . GLU A 1 44 ? 18.150 -4.225 36.956 1.00 26.38 ? 44 GLU A C 1 ATOM 279 O O . GLU A 1 44 ? 17.846 -3.757 38.049 1.00 25.86 ? 44 GLU A O 1 ATOM 280 C CB . GLU A 1 44 ? 18.424 -2.218 35.556 1.00 28.01 ? 44 GLU A CB 1 ATOM 281 C CG . GLU A 1 44 ? 17.175 -2.497 34.702 1.00 30.57 ? 44 GLU A CG 1 ATOM 282 C CD . GLU A 1 44 ? 17.078 -1.634 33.443 1.00 33.70 ? 44 GLU A CD 1 ATOM 283 O OE1 . GLU A 1 44 ? 18.087 -0.994 33.074 1.00 32.64 ? 44 GLU A OE1 1 ATOM 284 O OE2 . GLU A 1 44 ? 15.982 -1.610 32.816 1.00 35.54 ? 44 GLU A OE2 1 ATOM 285 N N . ILE A 1 45 ? 17.677 -5.379 36.483 1.00 25.68 ? 45 ILE A N 1 ATOM 286 C CA . ILE A 1 45 ? 16.550 -6.105 37.091 1.00 24.39 ? 45 ILE A CA 1 ATOM 287 C C . ILE A 1 45 ? 16.909 -7.502 37.609 1.00 24.19 ? 45 ILE A C 1 ATOM 288 O O . ILE A 1 45 ? 17.240 -8.366 36.821 1.00 24.29 ? 45 ILE A O 1 ATOM 289 C CB . ILE A 1 45 ? 15.393 -6.227 36.080 1.00 23.72 ? 45 ILE A CB 1 ATOM 290 C CG1 . ILE A 1 45 ? 15.111 -4.869 35.436 1.00 22.12 ? 45 ILE A CG1 1 ATOM 291 C CG2 . ILE A 1 45 ? 14.179 -6.779 36.753 1.00 23.70 ? 45 ILE A CG2 1 ATOM 292 C CD1 . ILE A 1 45 ? 13.662 -4.508 35.339 1.00 20.21 ? 45 ILE A CD1 1 ATOM 293 N N . ASP A 1 46 ? 16.852 -7.723 38.922 1.00 24.15 ? 46 ASP A N 1 ATOM 294 C CA . ASP A 1 46 ? 17.097 -9.067 39.464 1.00 24.43 ? 46 ASP A CA 1 ATOM 295 C C . ASP A 1 46 ? 15.776 -9.772 39.515 1.00 24.69 ? 46 ASP A C 1 ATOM 296 O O . ASP A 1 46 ? 14.954 -9.540 40.398 1.00 24.75 ? 46 ASP A O 1 ATOM 297 C CB . ASP A 1 46 ? 17.764 -9.065 40.856 1.00 24.48 ? 46 ASP A CB 1 ATOM 298 C CG . ASP A 1 46 ? 18.070 -10.484 41.381 1.00 23.95 ? 46 ASP A CG 1 ATOM 299 O OD1 . ASP A 1 46 ? 17.550 -11.470 40.810 1.00 22.68 ? 46 ASP A OD1 1 ATOM 300 O OD2 . ASP A 1 46 ? 18.835 -10.606 42.370 1.00 23.76 ? 46 ASP A OD2 1 ATOM 301 N N . ALA A 1 47 ? 15.576 -10.639 38.544 1.00 25.18 ? 47 ALA A N 1 ATOM 302 C CA . ALA A 1 47 ? 14.286 -11.244 38.358 1.00 25.79 ? 47 ALA A CA 1 ATOM 303 C C . ALA A 1 47 ? 14.082 -12.444 39.270 1.00 26.39 ? 47 ALA A C 1 ATOM 304 O O . ALA A 1 47 ? 13.003 -13.026 39.272 1.00 26.45 ? 47 ALA A O 1 ATOM 305 C CB . ALA A 1 47 ? 14.117 -11.617 36.909 1.00 25.69 ? 47 ALA A CB 1 ATOM 306 N N . SER A 1 48 ? 15.123 -12.812 40.026 1.00 27.47 ? 48 SER A N 1 ATOM 307 C CA . SER A 1 48 ? 15.043 -13.884 41.022 1.00 28.47 ? 48 SER A CA 1 ATOM 308 C C . SER A 1 48 ? 14.389 -13.402 42.333 1.00 29.34 ? 48 SER A C 1 ATOM 309 O O . SER A 1 48 ? 13.612 -14.125 42.959 1.00 29.20 ? 48 SER A O 1 ATOM 310 C CB . SER A 1 48 ? 16.426 -14.485 41.291 1.00 28.59 ? 48 SER A CB 1 ATOM 311 O OG . SER A 1 48 ? 17.274 -13.623 42.039 1.00 29.09 ? 48 SER A OG 1 ATOM 312 N N . LYS A 1 49 ? 14.689 -12.169 42.726 1.00 30.41 ? 49 LYS A N 1 ATOM 313 C CA . LYS A 1 49 ? 14.079 -11.570 43.900 1.00 31.86 ? 49 LYS A CA 1 ATOM 314 C C . LYS A 1 49 ? 12.553 -11.724 43.993 1.00 32.42 ? 49 LYS A C 1 ATOM 315 O O . LYS A 1 49 ? 11.802 -11.396 43.084 1.00 32.40 ? 49 LYS A O 1 ATOM 316 C CB . LYS A 1 49 ? 14.485 -10.099 44.047 1.00 32.28 ? 49 LYS A CB 1 ATOM 317 C CG . LYS A 1 49 ? 15.700 -9.868 44.948 1.00 34.02 ? 49 LYS A CG 1 ATOM 318 C CD . LYS A 1 49 ? 15.499 -8.625 45.818 1.00 36.34 ? 49 LYS A CD 1 ATOM 319 C CE . LYS A 1 49 ? 16.301 -8.714 47.139 1.00 38.51 ? 49 LYS A CE 1 ATOM 320 N NZ . LYS A 1 49 ? 15.792 -9.723 48.147 1.00 39.78 ? 49 LYS A NZ 1 ATOM 321 N N . THR A 1 50 ? 12.126 -12.199 45.151 1.00 33.42 ? 50 THR A N 1 ATOM 322 C CA . THR A 1 50 ? 10.764 -12.596 45.392 1.00 33.99 ? 50 THR A CA 1 ATOM 323 C C . THR A 1 50 ? 10.183 -11.880 46.629 1.00 34.30 ? 50 THR A C 1 ATOM 324 O O . THR A 1 50 ? 8.977 -11.639 46.699 1.00 33.94 ? 50 THR A O 1 ATOM 325 C CB . THR A 1 50 ? 10.751 -14.119 45.558 1.00 34.22 ? 50 THR A CB 1 ATOM 326 O OG1 . THR A 1 50 ? 9.424 -14.558 45.849 1.00 35.97 ? 50 THR A OG1 1 ATOM 327 C CG2 . THR A 1 50 ? 11.750 -14.581 46.662 1.00 33.37 ? 50 THR A CG2 1 ATOM 328 N N . CYS A 1 51 ? 11.052 -11.587 47.606 1.00 34.81 ? 51 CYS A N 1 ATOM 329 C CA . CYS A 1 51 ? 10.767 -10.669 48.709 1.00 35.37 ? 51 CYS A CA 1 ATOM 330 C C . CYS A 1 51 ? 11.684 -9.426 48.633 1.00 34.55 ? 51 CYS A C 1 ATOM 331 O O . CYS A 1 51 ? 12.599 -9.369 47.815 1.00 34.12 ? 51 CYS A O 1 ATOM 332 C CB . CYS A 1 51 ? 10.844 -11.381 50.084 1.00 36.07 ? 51 CYS A CB 1 ATOM 333 S SG . CYS A 1 51 ? 12.462 -12.091 50.744 1.00 41.39 ? 51 CYS A SG 1 ATOM 334 N N . TYR A 1 52 ? 11.425 -8.423 49.468 1.00 34.21 ? 52 TYR A N 1 ATOM 335 C CA . TYR A 1 52 ? 12.345 -7.278 49.612 1.00 33.70 ? 52 TYR A CA 1 ATOM 336 C C . TYR A 1 52 ? 12.963 -7.110 51.034 1.00 33.66 ? 52 TYR A C 1 ATOM 337 O O . TYR A 1 52 ? 12.386 -7.537 52.040 1.00 33.33 ? 52 TYR A O 1 ATOM 338 C CB . TYR A 1 52 ? 11.633 -6.008 49.232 1.00 33.40 ? 52 TYR A CB 1 ATOM 339 C CG . TYR A 1 52 ? 10.709 -5.504 50.312 1.00 32.68 ? 52 TYR A CG 1 ATOM 340 C CD1 . TYR A 1 52 ? 11.151 -4.573 51.281 1.00 31.03 ? 52 TYR A CD1 1 ATOM 341 C CD2 . TYR A 1 52 ? 9.401 -5.952 50.377 1.00 32.21 ? 52 TYR A CD2 1 ATOM 342 C CE1 . TYR A 1 52 ? 10.299 -4.095 52.260 1.00 29.15 ? 52 TYR A CE1 1 ATOM 343 C CE2 . TYR A 1 52 ? 8.543 -5.485 51.366 1.00 31.91 ? 52 TYR A CE2 1 ATOM 344 C CZ . TYR A 1 52 ? 8.995 -4.558 52.288 1.00 30.22 ? 52 TYR A CZ 1 ATOM 345 O OH . TYR A 1 52 ? 8.108 -4.124 53.228 1.00 31.15 ? 52 TYR A OH 1 ATOM 346 N N . HIS A 1 53 ? 14.114 -6.446 51.094 1.00 33.36 ? 53 HIS A N 1 ATOM 347 C CA . HIS A 1 53 ? 14.942 -6.439 52.276 1.00 33.18 ? 53 HIS A CA 1 ATOM 348 C C . HIS A 1 53 ? 14.898 -5.130 53.012 1.00 33.27 ? 53 HIS A C 1 ATOM 349 O O . HIS A 1 53 ? 15.342 -4.105 52.521 1.00 33.17 ? 53 HIS A O 1 ATOM 350 C CB . HIS A 1 53 ? 16.377 -6.759 51.910 1.00 33.20 ? 53 HIS A CB 1 ATOM 351 C CG . HIS A 1 53 ? 16.719 -8.201 52.055 1.00 34.95 ? 53 HIS A CG 1 ATOM 352 N ND1 . HIS A 1 53 ? 16.201 -9.172 51.227 1.00 35.78 ? 53 HIS A ND1 1 ATOM 353 C CD2 . HIS A 1 53 ? 17.523 -8.844 52.940 1.00 37.87 ? 53 HIS A CD2 1 ATOM 354 C CE1 . HIS A 1 53 ? 16.673 -10.351 51.595 1.00 38.31 ? 53 HIS A CE1 1 ATOM 355 N NE2 . HIS A 1 53 ? 17.478 -10.180 52.633 1.00 38.13 ? 53 HIS A NE2 1 ATOM 356 N N . GLY A 1 54 ? 14.382 -5.187 54.228 1.00 33.79 ? 54 GLY A N 1 ATOM 357 C CA . GLY A 1 54 ? 14.306 -4.025 55.092 1.00 33.81 ? 54 GLY A CA 1 ATOM 358 C C . GLY A 1 54 ? 13.123 -3.188 54.699 1.00 33.86 ? 54 GLY A C 1 ATOM 359 O O . GLY A 1 54 ? 11.974 -3.569 54.921 1.00 34.07 ? 54 GLY A O 1 ATOM 360 N N . ASN A 1 55 ? 13.411 -2.050 54.094 1.00 33.71 ? 55 ASN A N 1 ATOM 361 C CA . ASN A 1 55 ? 12.373 -1.129 53.707 1.00 33.86 ? 55 ASN A CA 1 ATOM 362 C C . ASN A 1 55 ? 12.064 -1.165 52.202 1.00 34.13 ? 55 ASN A C 1 ATOM 363 O O . ASN A 1 55 ? 10.939 -0.869 51.768 1.00 34.17 ? 55 ASN A O 1 ATOM 364 C CB . ASN A 1 55 ? 12.775 0.263 54.144 1.00 33.72 ? 55 ASN A CB 1 ATOM 365 C CG . ASN A 1 55 ? 12.852 1.203 53.000 1.00 34.09 ? 55 ASN A CG 1 ATOM 366 O OD1 . ASN A 1 55 ? 11.830 1.679 52.501 1.00 34.79 ? 55 ASN A OD1 1 ATOM 367 N ND2 . ASN A 1 55 ? 14.066 1.453 52.533 1.00 34.27 ? 55 ASN A ND2 1 ATOM 368 N N . GLY A 1 56 ? 13.074 -1.500 51.407 1.00 34.12 ? 56 GLY A N 1 ATOM 369 C CA . GLY A 1 56 ? 12.885 -1.621 49.990 1.00 33.82 ? 56 GLY A CA 1 ATOM 370 C C . GLY A 1 56 ? 13.792 -0.759 49.162 1.00 34.10 ? 56 GLY A C 1 ATOM 371 O O . GLY A 1 56 ? 14.002 -1.068 47.996 1.00 34.93 ? 56 GLY A O 1 ATOM 372 N N . ASP A 1 57 ? 14.332 0.321 49.732 1.00 33.84 ? 57 ASP A N 1 ATOM 373 C CA . ASP A 1 57 ? 15.168 1.272 48.968 1.00 33.40 ? 57 ASP A CA 1 ATOM 374 C C . ASP A 1 57 ? 16.056 0.543 47.939 1.00 32.76 ? 57 ASP A C 1 ATOM 375 O O . ASP A 1 57 ? 16.369 1.076 46.876 1.00 33.21 ? 57 ASP A O 1 ATOM 376 C CB . ASP A 1 57 ? 16.027 2.141 49.914 1.00 33.60 ? 57 ASP A CB 1 ATOM 377 C CG . ASP A 1 57 ? 15.811 3.672 49.710 1.00 35.03 ? 57 ASP A CG 1 ATOM 378 O OD1 . ASP A 1 57 ? 16.706 4.472 50.091 1.00 36.25 ? 57 ASP A OD1 1 ATOM 379 O OD2 . ASP A 1 57 ? 14.747 4.094 49.191 1.00 36.14 ? 57 ASP A OD2 1 ATOM 380 N N . SER A 1 58 ? 16.419 -0.696 48.250 1.00 31.72 ? 58 SER A N 1 ATOM 381 C CA . SER A 1 58 ? 17.259 -1.506 47.393 1.00 30.69 ? 58 SER A CA 1 ATOM 382 C C . SER A 1 58 ? 16.504 -2.374 46.360 1.00 30.12 ? 58 SER A C 1 ATOM 383 O O . SER A 1 58 ? 17.093 -2.794 45.351 1.00 29.84 ? 58 SER A O 1 ATOM 384 C CB . SER A 1 58 ? 18.099 -2.403 48.276 1.00 30.75 ? 58 SER A CB 1 ATOM 385 O OG . SER A 1 58 ? 19.075 -3.078 47.521 1.00 31.04 ? 58 SER A OG 1 ATOM 386 N N . TYR A 1 59 ? 15.221 -2.644 46.614 1.00 29.19 ? 59 TYR A N 1 ATOM 387 C CA . TYR A 1 59 ? 14.437 -3.599 45.826 1.00 28.45 ? 59 TYR A CA 1 ATOM 388 C C . TYR A 1 59 ? 14.393 -3.292 44.345 1.00 28.72 ? 59 TYR A C 1 ATOM 389 O O . TYR A 1 59 ? 13.938 -2.214 43.935 1.00 29.42 ? 59 TYR A O 1 ATOM 390 C CB . TYR A 1 59 ? 13.019 -3.676 46.335 1.00 27.90 ? 59 TYR A CB 1 ATOM 391 C CG . TYR A 1 59 ? 12.101 -4.551 45.510 1.00 27.58 ? 59 TYR A CG 1 ATOM 392 C CD1 . TYR A 1 59 ? 12.174 -5.921 45.577 1.00 28.42 ? 59 TYR A CD1 1 ATOM 393 C CD2 . TYR A 1 59 ? 11.129 -4.006 44.700 1.00 27.43 ? 59 TYR A CD2 1 ATOM 394 C CE1 . TYR A 1 59 ? 11.302 -6.725 44.859 1.00 28.48 ? 59 TYR A CE1 1 ATOM 395 C CE2 . TYR A 1 59 ? 10.261 -4.800 43.979 1.00 27.20 ? 59 TYR A CE2 1 ATOM 396 C CZ . TYR A 1 59 ? 10.349 -6.160 44.061 1.00 27.78 ? 59 TYR A CZ 1 ATOM 397 O OH . TYR A 1 59 ? 9.500 -6.975 43.331 1.00 28.19 ? 59 TYR A OH 1 ATOM 398 N N . ARG A 1 60 ? 14.855 -4.245 43.543 1.00 28.09 ? 60 ARG A N 1 ATOM 399 C CA . ARG A 1 60 ? 14.857 -4.073 42.110 1.00 27.34 ? 60 ARG A CA 1 ATOM 400 C C . ARG A 1 60 ? 14.053 -5.187 41.436 1.00 27.70 ? 60 ARG A C 1 ATOM 401 O O . ARG A 1 60 ? 14.243 -5.518 40.263 1.00 28.15 ? 60 ARG A O 1 ATOM 402 C CB . ARG A 1 60 ? 16.288 -3.972 41.596 1.00 26.66 ? 60 ARG A CB 1 ATOM 403 C CG . ARG A 1 60 ? 17.008 -2.730 42.099 1.00 26.23 ? 60 ARG A CG 1 ATOM 404 C CD . ARG A 1 60 ? 16.232 -1.435 41.813 1.00 24.99 ? 60 ARG A CD 1 ATOM 405 N NE . ARG A 1 60 ? 16.370 -0.443 42.890 1.00 23.50 ? 60 ARG A NE 1 ATOM 406 C CZ . ARG A 1 60 ? 17.299 0.511 42.933 1.00 21.73 ? 60 ARG A CZ 1 ATOM 407 N NH1 . ARG A 1 60 ? 18.201 0.636 41.957 1.00 21.27 ? 60 ARG A NH1 1 ATOM 408 N NH2 . ARG A 1 60 ? 17.316 1.347 43.953 1.00 19.48 ? 60 ARG A NH2 1 ATOM 409 N N . GLY A 1 61 ? 13.117 -5.762 42.175 1.00 27.45 ? 61 GLY A N 1 ATOM 410 C CA . GLY A 1 61 ? 12.409 -6.910 41.649 1.00 26.98 ? 61 GLY A CA 1 ATOM 411 C C . GLY A 1 61 ? 11.290 -6.463 40.748 1.00 26.76 ? 61 GLY A C 1 ATOM 412 O O . GLY A 1 61 ? 11.334 -5.357 40.206 1.00 26.82 ? 61 GLY A O 1 ATOM 413 N N . LYS A 1 62 ? 10.274 -7.321 40.634 1.00 26.30 ? 62 LYS A N 1 ATOM 414 C CA . LYS A 1 62 ? 9.271 -7.226 39.598 1.00 25.64 ? 62 LYS A CA 1 ATOM 415 C C . LYS A 1 62 ? 7.850 -7.345 40.093 1.00 26.13 ? 62 LYS A C 1 ATOM 416 O O . LYS A 1 62 ? 6.966 -7.793 39.343 1.00 26.15 ? 62 LYS A O 1 ATOM 417 C CB . LYS A 1 62 ? 9.515 -8.277 38.541 1.00 24.80 ? 62 LYS A CB 1 ATOM 418 C CG . LYS A 1 62 ? 10.912 -8.241 38.021 1.00 24.40 ? 62 LYS A CG 1 ATOM 419 C CD . LYS A 1 62 ? 10.994 -8.634 36.542 1.00 24.67 ? 62 LYS A CD 1 ATOM 420 C CE . LYS A 1 62 ? 10.789 -10.099 36.297 1.00 22.42 ? 62 LYS A CE 1 ATOM 421 N NZ . LYS A 1 62 ? 10.656 -10.276 34.870 1.00 23.45 ? 62 LYS A NZ 1 ATOM 422 N N . ALA A 1 63 ? 7.605 -6.937 41.333 1.00 26.36 ? 63 ALA A N 1 ATOM 423 C CA . ALA A 1 63 ? 6.222 -6.796 41.760 1.00 27.12 ? 63 ALA A CA 1 ATOM 424 C C . ALA A 1 63 ? 5.610 -5.719 40.900 1.00 27.83 ? 63 ALA A C 1 ATOM 425 O O . ALA A 1 63 ? 6.240 -4.693 40.655 1.00 28.51 ? 63 ALA A O 1 ATOM 426 C CB . ALA A 1 63 ? 6.145 -6.400 43.182 1.00 27.10 ? 63 ALA A CB 1 ATOM 427 N N . ASN A 1 64 ? 4.403 -5.935 40.405 1.00 28.31 ? 64 ASN A N 1 ATOM 428 C CA . ASN A 1 64 ? 3.757 -4.864 39.667 1.00 28.55 ? 64 ASN A CA 1 ATOM 429 C C . ASN A 1 64 ? 2.331 -4.608 40.102 1.00 28.78 ? 64 ASN A C 1 ATOM 430 O O . ASN A 1 64 ? 1.702 -3.713 39.597 1.00 29.48 ? 64 ASN A O 1 ATOM 431 C CB . ASN A 1 64 ? 3.822 -5.116 38.174 1.00 28.29 ? 64 ASN A CB 1 ATOM 432 C CG . ASN A 1 64 ? 3.269 -6.456 37.808 1.00 29.55 ? 64 ASN A CG 1 ATOM 433 O OD1 . ASN A 1 64 ? 4.000 -7.344 37.393 1.00 31.05 ? 64 ASN A OD1 1 ATOM 434 N ND2 . ASN A 1 64 ? 1.974 -6.636 38.002 1.00 31.84 ? 64 ASN A ND2 1 ATOM 435 N N . THR A 1 65 ? 1.784 -5.369 41.029 1.00 29.04 ? 65 THR A N 1 ATOM 436 C CA . THR A 1 65 ? 0.429 -5.019 41.423 1.00 29.33 ? 65 THR A CA 1 ATOM 437 C C . THR A 1 65 ? 0.366 -4.333 42.783 1.00 29.31 ? 65 THR A C 1 ATOM 438 O O . THR A 1 65 ? 1.390 -4.009 43.387 1.00 28.82 ? 65 THR A O 1 ATOM 439 C CB . THR A 1 65 ? -0.593 -6.184 41.251 1.00 29.44 ? 65 THR A CB 1 ATOM 440 O OG1 . THR A 1 65 ? -0.208 -7.304 42.039 1.00 29.22 ? 65 THR A OG1 1 ATOM 441 C CG2 . THR A 1 65 ? -0.666 -6.623 39.787 1.00 30.03 ? 65 THR A CG2 1 ATOM 442 N N . ASP A 1 66 ? -0.851 -4.080 43.234 1.00 29.36 ? 66 ASP A N 1 ATOM 443 C CA . ASP A 1 66 ? -1.042 -3.381 44.475 1.00 29.70 ? 66 ASP A CA 1 ATOM 444 C C . ASP A 1 66 ? -1.952 -4.184 45.388 1.00 29.64 ? 66 ASP A C 1 ATOM 445 O O . ASP A 1 66 ? -2.658 -5.103 44.963 1.00 29.72 ? 66 ASP A O 1 ATOM 446 C CB . ASP A 1 66 ? -1.585 -1.962 44.240 1.00 29.82 ? 66 ASP A CB 1 ATOM 447 C CG . ASP A 1 66 ? -3.103 -1.926 43.927 1.00 32.05 ? 66 ASP A CG 1 ATOM 448 O OD1 . ASP A 1 66 ? -3.721 -2.992 43.674 1.00 34.68 ? 66 ASP A OD1 1 ATOM 449 O OD2 . ASP A 1 66 ? -3.690 -0.812 43.924 1.00 33.74 ? 66 ASP A OD2 1 ATOM 450 N N . THR A 1 67 ? -1.933 -3.797 46.649 1.00 29.48 ? 67 THR A N 1 ATOM 451 C CA . THR A 1 67 ? -2.559 -4.509 47.724 1.00 29.36 ? 67 THR A CA 1 ATOM 452 C C . THR A 1 67 ? -4.094 -4.556 47.634 1.00 29.84 ? 67 THR A C 1 ATOM 453 O O . THR A 1 67 ? -4.766 -4.984 48.592 1.00 30.23 ? 67 THR A O 1 ATOM 454 C CB . THR A 1 67 ? -2.092 -3.880 49.027 1.00 29.29 ? 67 THR A CB 1 ATOM 455 O OG1 . THR A 1 67 ? -1.964 -2.472 48.819 1.00 28.85 ? 67 THR A OG1 1 ATOM 456 C CG2 . THR A 1 67 ? -0.716 -4.421 49.418 1.00 29.04 ? 67 THR A CG2 1 ATOM 457 N N . LYS A 1 68 ? -4.650 -4.129 46.494 1.00 29.92 ? 68 LYS A N 1 ATOM 458 C CA . LYS A 1 68 ? -6.087 -4.340 46.194 1.00 29.66 ? 68 LYS A CA 1 ATOM 459 C C . LYS A 1 68 ? -6.319 -5.127 44.894 1.00 29.53 ? 68 LYS A C 1 ATOM 460 O O . LYS A 1 68 ? -7.429 -5.602 44.642 1.00 29.55 ? 68 LYS A O 1 ATOM 461 C CB . LYS A 1 68 ? -6.876 -3.021 46.212 1.00 29.42 ? 68 LYS A CB 1 ATOM 462 C CG . LYS A 1 68 ? -7.261 -2.568 47.605 1.00 29.06 ? 68 LYS A CG 1 ATOM 463 C CD . LYS A 1 68 ? -7.689 -1.114 47.629 1.00 29.21 ? 68 LYS A CD 1 ATOM 464 C CE . LYS A 1 68 ? -8.015 -0.679 49.051 1.00 29.35 ? 68 LYS A CE 1 ATOM 465 N NZ . LYS A 1 68 ? -9.075 0.368 49.096 1.00 29.17 ? 68 LYS A NZ 1 ATOM 466 N N . GLY A 1 69 ? -5.263 -5.276 44.097 1.00 29.30 ? 69 GLY A N 1 ATOM 467 C CA . GLY A 1 69 ? -5.330 -5.989 42.828 1.00 29.69 ? 69 GLY A CA 1 ATOM 468 C C . GLY A 1 69 ? -4.705 -5.206 41.681 1.00 29.93 ? 69 GLY A C 1 ATOM 469 O O . GLY A 1 69 ? -3.822 -5.707 40.966 1.00 30.11 ? 69 GLY A O 1 ATOM 470 N N . ARG A 1 70 ? -5.172 -3.968 41.523 1.00 29.78 ? 70 ARG A N 1 ATOM 471 C CA . ARG A 1 70 ? -4.781 -3.034 40.442 1.00 29.18 ? 70 ARG A CA 1 ATOM 472 C C . ARG A 1 70 ? -3.326 -3.127 39.966 1.00 28.43 ? 70 ARG A C 1 ATOM 473 O O . ARG A 1 70 ? -2.429 -3.394 40.745 1.00 27.92 ? 70 ARG A O 1 ATOM 474 C CB . ARG A 1 70 ? -5.157 -1.598 40.850 1.00 29.23 ? 70 ARG A CB 1 ATOM 475 C CG . ARG A 1 70 ? -6.536 -1.539 41.555 1.00 30.04 ? 70 ARG A CG 1 ATOM 476 C CD . ARG A 1 70 ? -6.975 -0.130 41.930 1.00 31.68 ? 70 ARG A CD 1 ATOM 477 N NE . ARG A 1 70 ? -6.385 0.356 43.180 1.00 32.52 ? 70 ARG A NE 1 ATOM 478 C CZ . ARG A 1 70 ? -7.077 0.756 44.246 1.00 33.16 ? 70 ARG A CZ 1 ATOM 479 N NH1 . ARG A 1 70 ? -8.412 0.745 44.253 1.00 33.14 ? 70 ARG A NH1 1 ATOM 480 N NH2 . ARG A 1 70 ? -6.423 1.175 45.316 1.00 33.25 ? 70 ARG A NH2 1 ATOM 481 N N . PRO A 1 71 ? -3.098 -2.930 38.664 1.00 28.44 ? 71 PRO A N 1 ATOM 482 C CA . PRO A 1 71 ? -1.710 -2.956 38.191 1.00 28.34 ? 71 PRO A CA 1 ATOM 483 C C . PRO A 1 71 ? -1.040 -1.594 38.287 1.00 28.06 ? 71 PRO A C 1 ATOM 484 O O . PRO A 1 71 ? -1.704 -0.587 38.240 1.00 27.64 ? 71 PRO A O 1 ATOM 485 C CB . PRO A 1 71 ? -1.837 -3.405 36.722 1.00 28.21 ? 71 PRO A CB 1 ATOM 486 C CG . PRO A 1 71 ? -3.376 -3.535 36.438 1.00 28.17 ? 71 PRO A CG 1 ATOM 487 C CD . PRO A 1 71 ? -4.069 -2.826 37.555 1.00 28.38 ? 71 PRO A CD 1 ATOM 488 N N . CYS A 1 72 ? 0.275 -1.586 38.426 1.00 28.88 ? 72 CYS A N 1 ATOM 489 C CA . CYS A 1 72 ? 1.074 -0.361 38.511 1.00 30.10 ? 72 CYS A CA 1 ATOM 490 C C . CYS A 1 72 ? 1.133 0.295 37.173 1.00 29.95 ? 72 CYS A C 1 ATOM 491 O O . CYS A 1 72 ? 1.009 -0.380 36.156 1.00 30.24 ? 72 CYS A O 1 ATOM 492 C CB . CYS A 1 72 ? 2.540 -0.651 38.892 1.00 30.65 ? 72 CYS A CB 1 ATOM 493 S SG . CYS A 1 72 ? 2.874 -1.237 40.578 1.00 33.37 ? 72 CYS A SG 1 ATOM 494 N N . LEU A 1 73 ? 1.363 1.603 37.166 1.00 29.92 ? 73 LEU A N 1 ATOM 495 C CA . LEU A 1 73 ? 1.524 2.304 35.916 1.00 30.06 ? 73 LEU A CA 1 ATOM 496 C C . LEU A 1 73 ? 3.001 2.365 35.604 1.00 30.67 ? 73 LEU A C 1 ATOM 497 O O . LEU A 1 73 ? 3.827 2.394 36.509 1.00 31.06 ? 73 LEU A O 1 ATOM 498 C CB . LEU A 1 73 ? 0.862 3.686 35.948 1.00 29.59 ? 73 LEU A CB 1 ATOM 499 C CG . LEU A 1 73 ? -0.662 3.641 36.135 1.00 28.34 ? 73 LEU A CG 1 ATOM 500 C CD1 . LEU A 1 73 ? -1.235 5.029 36.179 1.00 27.34 ? 73 LEU A CD1 1 ATOM 501 C CD2 . LEU A 1 73 ? -1.362 2.808 35.081 1.00 26.10 ? 73 LEU A CD2 1 ATOM 502 N N . ALA A 1 74 ? 3.330 2.358 34.318 1.00 31.23 ? 74 ALA A N 1 ATOM 503 C CA . ALA A 1 74 ? 4.713 2.355 33.888 1.00 31.71 ? 74 ALA A CA 1 ATOM 504 C C . ALA A 1 74 ? 5.378 3.656 34.274 1.00 32.05 ? 74 ALA A C 1 ATOM 505 O O . ALA A 1 74 ? 4.799 4.723 34.083 1.00 32.02 ? 74 ALA A O 1 ATOM 506 C CB . ALA A 1 74 ? 4.782 2.162 32.394 1.00 31.95 ? 74 ALA A CB 1 ATOM 507 N N . TRP A 1 75 ? 6.588 3.572 34.818 1.00 32.47 ? 75 TRP A N 1 ATOM 508 C CA . TRP A 1 75 ? 7.389 4.772 35.055 1.00 33.04 ? 75 TRP A CA 1 ATOM 509 C C . TRP A 1 75 ? 7.583 5.560 33.759 1.00 33.15 ? 75 TRP A C 1 ATOM 510 O O . TRP A 1 75 ? 7.930 6.721 33.798 1.00 32.94 ? 75 TRP A O 1 ATOM 511 C CB . TRP A 1 75 ? 8.731 4.429 35.707 1.00 33.04 ? 75 TRP A CB 1 ATOM 512 C CG . TRP A 1 75 ? 8.583 3.546 36.915 1.00 33.76 ? 75 TRP A CG 1 ATOM 513 C CD1 . TRP A 1 75 ? 8.854 2.222 36.983 1.00 35.43 ? 75 TRP A CD1 1 ATOM 514 C CD2 . TRP A 1 75 ? 8.101 3.915 38.215 1.00 34.12 ? 75 TRP A CD2 1 ATOM 515 N NE1 . TRP A 1 75 ? 8.575 1.729 38.240 1.00 33.74 ? 75 TRP A NE1 1 ATOM 516 C CE2 . TRP A 1 75 ? 8.130 2.762 39.019 1.00 34.26 ? 75 TRP A CE2 1 ATOM 517 C CE3 . TRP A 1 75 ? 7.673 5.113 38.788 1.00 34.68 ? 75 TRP A CE3 1 ATOM 518 C CZ2 . TRP A 1 75 ? 7.742 2.776 40.368 1.00 34.42 ? 75 TRP A CZ2 1 ATOM 519 C CZ3 . TRP A 1 75 ? 7.292 5.120 40.140 1.00 33.64 ? 75 TRP A CZ3 1 ATOM 520 C CH2 . TRP A 1 75 ? 7.326 3.962 40.903 1.00 32.90 ? 75 TRP A CH2 1 ATOM 521 N N . ASN A 1 76 ? 7.347 4.901 32.625 1.00 33.89 ? 76 ASN A N 1 ATOM 522 C CA . ASN A 1 76 ? 7.231 5.514 31.302 1.00 34.47 ? 76 ASN A CA 1 ATOM 523 C C . ASN A 1 76 ? 6.070 6.425 31.160 1.00 34.24 ? 76 ASN A C 1 ATOM 524 O O . ASN A 1 76 ? 6.240 7.557 30.773 1.00 34.43 ? 76 ASN A O 1 ATOM 525 C CB . ASN A 1 76 ? 6.916 4.444 30.293 1.00 35.17 ? 76 ASN A CB 1 ATOM 526 C CG . ASN A 1 76 ? 8.096 4.017 29.529 1.00 38.37 ? 76 ASN A CG 1 ATOM 527 O OD1 . ASN A 1 76 ? 8.025 3.023 28.787 1.00 41.45 ? 76 ASN A OD1 1 ATOM 528 N ND2 . ASN A 1 76 ? 9.213 4.751 29.682 1.00 39.99 ? 76 ASN A ND2 1 ATOM 529 N N . ALA A 1 77 ? 4.883 5.882 31.437 1.00 34.28 ? 77 ALA A N 1 ATOM 530 C CA . ALA A 1 77 ? 3.577 6.480 31.132 1.00 34.39 ? 77 ALA A CA 1 ATOM 531 C C . ALA A 1 77 ? 3.559 7.968 30.923 1.00 34.88 ? 77 ALA A C 1 ATOM 532 O O . ALA A 1 77 ? 4.159 8.728 31.703 1.00 35.07 ? 77 ALA A O 1 ATOM 533 C CB . ALA A 1 77 ? 2.570 6.136 32.190 1.00 34.37 ? 77 ALA A CB 1 ATOM 534 N N . PRO A 1 78 ? 2.834 8.401 29.880 1.00 35.17 ? 78 PRO A N 1 ATOM 535 C CA . PRO A 1 78 ? 2.599 9.828 29.707 1.00 35.21 ? 78 PRO A CA 1 ATOM 536 C C . PRO A 1 78 ? 1.933 10.377 30.981 1.00 35.24 ? 78 PRO A C 1 ATOM 537 O O . PRO A 1 78 ? 2.288 11.462 31.459 1.00 35.02 ? 78 PRO A O 1 ATOM 538 C CB . PRO A 1 78 ? 1.650 9.878 28.503 1.00 35.30 ? 78 PRO A CB 1 ATOM 539 C CG . PRO A 1 78 ? 1.807 8.552 27.819 1.00 35.07 ? 78 PRO A CG 1 ATOM 540 C CD . PRO A 1 78 ? 2.089 7.587 28.902 1.00 34.97 ? 78 PRO A CD 1 ATOM 541 N N . ALA A 1 79 ? 1.001 9.592 31.532 1.00 35.33 ? 79 ALA A N 1 ATOM 542 C CA . ALA A 1 79 ? 0.369 9.869 32.821 1.00 35.28 ? 79 ALA A CA 1 ATOM 543 C C . ALA A 1 79 ? 1.423 10.194 33.889 1.00 35.26 ? 79 ALA A C 1 ATOM 544 O O . ALA A 1 79 ? 1.536 11.334 34.342 1.00 35.08 ? 79 ALA A O 1 ATOM 545 C CB . ALA A 1 79 ? -0.479 8.679 33.238 1.00 34.84 ? 79 ALA A CB 1 ATOM 546 N N . VAL A 1 80 ? 2.222 9.185 34.228 1.00 35.35 ? 80 VAL A N 1 ATOM 547 C CA . VAL A 1 80 ? 3.263 9.250 35.263 1.00 35.29 ? 80 VAL A CA 1 ATOM 548 C C . VAL A 1 80 ? 4.338 10.331 35.044 1.00 35.35 ? 80 VAL A C 1 ATOM 549 O O . VAL A 1 80 ? 4.937 10.829 36.008 1.00 35.61 ? 80 VAL A O 1 ATOM 550 C CB . VAL A 1 80 ? 3.948 7.857 35.421 1.00 35.33 ? 80 VAL A CB 1 ATOM 551 C CG1 . VAL A 1 80 ? 5.073 7.884 36.466 1.00 34.89 ? 80 VAL A CG1 1 ATOM 552 C CG2 . VAL A 1 80 ? 2.911 6.787 35.766 1.00 35.55 ? 80 VAL A CG2 1 ATOM 553 N N . LEU A 1 81 ? 4.594 10.698 33.794 1.00 35.00 ? 81 LEU A N 1 ATOM 554 C CA . LEU A 1 81 ? 5.628 11.697 33.540 1.00 34.64 ? 81 LEU A CA 1 ATOM 555 C C . LEU A 1 81 ? 5.344 13.086 34.142 1.00 34.23 ? 81 LEU A C 1 ATOM 556 O O . LEU A 1 81 ? 6.235 13.934 34.172 1.00 33.77 ? 81 LEU A O 1 ATOM 557 C CB . LEU A 1 81 ? 5.995 11.766 32.054 1.00 34.79 ? 81 LEU A CB 1 ATOM 558 C CG . LEU A 1 81 ? 7.237 10.944 31.692 1.00 34.53 ? 81 LEU A CG 1 ATOM 559 C CD1 . LEU A 1 81 ? 7.268 10.621 30.221 1.00 34.99 ? 81 LEU A CD1 1 ATOM 560 C CD2 . LEU A 1 81 ? 8.492 11.684 32.082 1.00 34.04 ? 81 LEU A CD2 1 ATOM 561 N N . GLN A 1 82 ? 4.121 13.294 34.634 1.00 33.91 ? 82 GLN A N 1 ATOM 562 C CA . GLN A 1 82 ? 3.792 14.495 35.406 1.00 33.93 ? 82 GLN A CA 1 ATOM 563 C C . GLN A 1 82 ? 4.212 14.300 36.854 1.00 33.67 ? 82 GLN A C 1 ATOM 564 O O . GLN A 1 82 ? 4.653 15.246 37.517 1.00 33.64 ? 82 GLN A O 1 ATOM 565 C CB . GLN A 1 82 ? 2.291 14.820 35.378 1.00 34.11 ? 82 GLN A CB 1 ATOM 566 C CG . GLN A 1 82 ? 1.521 14.377 34.133 1.00 35.47 ? 82 GLN A CG 1 ATOM 567 C CD . GLN A 1 82 ? 2.019 15.020 32.849 1.00 36.64 ? 82 GLN A CD 1 ATOM 568 O OE1 . GLN A 1 82 ? 1.885 16.233 32.645 1.00 36.79 ? 82 GLN A OE1 1 ATOM 569 N NE2 . GLN A 1 82 ? 2.587 14.201 31.967 1.00 36.95 ? 82 GLN A NE2 1 ATOM 570 N N . LYS A 1 83 ? 4.048 13.073 37.351 1.00 33.22 ? 83 LYS A N 1 ATOM 571 C CA . LYS A 1 83 ? 4.402 12.751 38.735 1.00 32.82 ? 83 LYS A CA 1 ATOM 572 C C . LYS A 1 83 ? 5.915 12.914 38.955 1.00 32.89 ? 83 LYS A C 1 ATOM 573 O O . LYS A 1 83 ? 6.690 12.758 38.010 1.00 33.10 ? 83 LYS A O 1 ATOM 574 C CB . LYS A 1 83 ? 3.910 11.353 39.087 1.00 32.19 ? 83 LYS A CB 1 ATOM 575 C CG . LYS A 1 83 ? 2.428 11.199 38.902 1.00 31.29 ? 83 LYS A CG 1 ATOM 576 C CD . LYS A 1 83 ? 1.700 11.627 40.147 1.00 32.28 ? 83 LYS A CD 1 ATOM 577 C CE . LYS A 1 83 ? 0.210 11.767 39.914 1.00 32.49 ? 83 LYS A CE 1 ATOM 578 N NZ . LYS A 1 83 ? -0.471 12.191 41.172 1.00 32.24 ? 83 LYS A NZ 1 ATOM 579 N N . PRO A 1 84 ? 6.336 13.259 40.188 1.00 32.69 ? 84 PRO A N 1 ATOM 580 C CA . PRO A 1 84 ? 7.730 13.660 40.401 1.00 32.67 ? 84 PRO A CA 1 ATOM 581 C C . PRO A 1 84 ? 8.728 12.528 40.192 1.00 32.57 ? 84 PRO A C 1 ATOM 582 O O . PRO A 1 84 ? 9.834 12.732 39.670 1.00 32.44 ? 84 PRO A O 1 ATOM 583 C CB . PRO A 1 84 ? 7.742 14.125 41.860 1.00 32.64 ? 84 PRO A CB 1 ATOM 584 C CG . PRO A 1 84 ? 6.316 14.435 42.167 1.00 33.01 ? 84 PRO A CG 1 ATOM 585 C CD . PRO A 1 84 ? 5.546 13.399 41.419 1.00 32.62 ? 84 PRO A CD 1 ATOM 586 N N . TYR A 1 85 ? 8.328 11.334 40.592 1.00 32.63 ? 85 TYR A N 1 ATOM 587 C CA . TYR A 1 85 ? 9.194 10.181 40.474 1.00 32.31 ? 85 TYR A CA 1 ATOM 588 C C . TYR A 1 85 ? 8.755 9.422 39.265 1.00 32.17 ? 85 TYR A C 1 ATOM 589 O O . TYR A 1 85 ? 7.689 8.798 39.268 1.00 31.81 ? 85 TYR A O 1 ATOM 590 C CB . TYR A 1 85 ? 9.105 9.334 41.741 1.00 32.38 ? 85 TYR A CB 1 ATOM 591 C CG . TYR A 1 85 ? 9.639 10.059 42.971 1.00 31.68 ? 85 TYR A CG 1 ATOM 592 C CD1 . TYR A 1 85 ? 11.012 10.215 43.164 1.00 30.77 ? 85 TYR A CD1 1 ATOM 593 C CD2 . TYR A 1 85 ? 8.779 10.597 43.919 1.00 30.30 ? 85 TYR A CD2 1 ATOM 594 C CE1 . TYR A 1 85 ? 11.513 10.869 44.267 1.00 31.10 ? 85 TYR A CE1 1 ATOM 595 C CE2 . TYR A 1 85 ? 9.278 11.255 45.035 1.00 31.32 ? 85 TYR A CE2 1 ATOM 596 C CZ . TYR A 1 85 ? 10.651 11.382 45.203 1.00 31.47 ? 85 TYR A CZ 1 ATOM 597 O OH . TYR A 1 85 ? 11.175 12.033 46.300 1.00 32.63 ? 85 TYR A OH 1 ATOM 598 N N . ASN A 1 86 ? 9.562 9.535 38.212 1.00 32.26 ? 86 ASN A N 1 ATOM 599 C CA . ASN A 1 86 ? 9.276 8.885 36.926 1.00 32.07 ? 86 ASN A CA 1 ATOM 600 C C . ASN A 1 86 ? 10.530 8.638 36.088 1.00 31.91 ? 86 ASN A C 1 ATOM 601 O O . ASN A 1 86 ? 11.592 9.154 36.390 1.00 31.96 ? 86 ASN A O 1 ATOM 602 C CB . ASN A 1 86 ? 8.207 9.662 36.143 1.00 32.01 ? 86 ASN A CB 1 ATOM 603 C CG . ASN A 1 86 ? 8.701 10.995 35.612 1.00 31.71 ? 86 ASN A CG 1 ATOM 604 O OD1 . ASN A 1 86 ? 7.907 11.921 35.447 1.00 31.60 ? 86 ASN A OD1 1 ATOM 605 N ND2 . ASN A 1 86 ? 10.003 11.097 35.318 1.00 30.61 ? 86 ASN A ND2 1 ATOM 606 N N . ALA A 1 87 ? 10.396 7.871 35.023 1.00 32.02 ? 87 ALA A N 1 ATOM 607 C CA . ALA A 1 87 ? 11.562 7.350 34.323 1.00 32.48 ? 87 ALA A CA 1 ATOM 608 C C . ALA A 1 87 ? 12.452 8.375 33.626 1.00 32.70 ? 87 ALA A C 1 ATOM 609 O O . ALA A 1 87 ? 13.582 8.059 33.243 1.00 32.91 ? 87 ALA A O 1 ATOM 610 C CB . ALA A 1 87 ? 11.151 6.253 33.352 1.00 32.72 ? 87 ALA A CB 1 ATOM 611 N N . HIS A 1 88 ? 11.968 9.591 33.441 1.00 33.04 ? 88 HIS A N 1 ATOM 612 C CA . HIS A 1 88 ? 12.812 10.569 32.771 1.00 33.58 ? 88 HIS A CA 1 ATOM 613 C C . HIS A 1 88 ? 13.747 11.277 33.740 1.00 33.82 ? 88 HIS A C 1 ATOM 614 O O . HIS A 1 88 ? 14.741 11.849 33.312 1.00 33.97 ? 88 HIS A O 1 ATOM 615 C CB . HIS A 1 88 ? 11.985 11.544 31.935 1.00 33.68 ? 88 HIS A CB 1 ATOM 616 C CG . HIS A 1 88 ? 11.556 10.988 30.610 1.00 34.05 ? 88 HIS A CG 1 ATOM 617 N ND1 . HIS A 1 88 ? 10.890 11.742 29.668 1.00 34.48 ? 88 HIS A ND1 1 ATOM 618 C CD2 . HIS A 1 88 ? 11.716 9.760 30.061 1.00 34.34 ? 88 HIS A CD2 1 ATOM 619 C CE1 . HIS A 1 88 ? 10.643 10.998 28.604 1.00 34.16 ? 88 HIS A CE1 1 ATOM 620 N NE2 . HIS A 1 88 ? 11.139 9.792 28.816 1.00 33.81 ? 88 HIS A NE2 1 ATOM 621 N N . ARG A 1 89 ? 13.437 11.221 35.037 1.00 34.19 ? 89 ARG A N 1 ATOM 622 C CA . ARG A 1 89 ? 14.314 11.743 36.085 1.00 34.61 ? 89 ARG A CA 1 ATOM 623 C C . ARG A 1 89 ? 15.749 11.595 35.653 1.00 34.93 ? 89 ARG A C 1 ATOM 624 O O . ARG A 1 89 ? 16.133 10.552 35.119 1.00 34.61 ? 89 ARG A O 1 ATOM 625 C CB . ARG A 1 89 ? 14.147 10.965 37.397 1.00 34.72 ? 89 ARG A CB 1 ATOM 626 C CG . ARG A 1 89 ? 12.975 11.361 38.274 1.00 35.69 ? 89 ARG A CG 1 ATOM 627 C CD . ARG A 1 89 ? 13.185 12.738 38.887 1.00 38.40 ? 89 ARG A CD 1 ATOM 628 N NE . ARG A 1 89 ? 14.144 12.706 39.988 1.00 39.24 ? 89 ARG A NE 1 ATOM 629 C CZ . ARG A 1 89 ? 13.812 12.562 41.267 1.00 38.78 ? 89 ARG A CZ 1 ATOM 630 N NH1 . ARG A 1 89 ? 12.539 12.443 41.615 1.00 38.79 ? 89 ARG A NH1 1 ATOM 631 N NH2 . ARG A 1 89 ? 14.757 12.540 42.194 1.00 38.69 ? 89 ARG A NH2 1 ATOM 632 N N . PRO A 1 90 ? 16.555 12.635 35.880 1.00 35.51 ? 90 PRO A N 1 ATOM 633 C CA . PRO A 1 90 ? 17.983 12.551 35.574 1.00 36.10 ? 90 PRO A CA 1 ATOM 634 C C . PRO A 1 90 ? 18.684 11.481 36.405 1.00 36.77 ? 90 PRO A C 1 ATOM 635 O O . PRO A 1 90 ? 19.733 10.985 36.008 1.00 37.06 ? 90 PRO A O 1 ATOM 636 C CB . PRO A 1 90 ? 18.508 13.942 35.942 1.00 35.91 ? 90 PRO A CB 1 ATOM 637 C CG . PRO A 1 90 ? 17.320 14.833 35.862 1.00 35.67 ? 90 PRO A CG 1 ATOM 638 C CD . PRO A 1 90 ? 16.152 13.991 36.287 1.00 35.66 ? 90 PRO A CD 1 ATOM 639 N N . ASP A 1 91 ? 18.084 11.123 37.536 1.00 37.59 ? 91 ASP A N 1 ATOM 640 C CA . ASP A 1 91 ? 18.673 10.197 38.507 1.00 38.37 ? 91 ASP A CA 1 ATOM 641 C C . ASP A 1 91 ? 18.121 8.783 38.371 1.00 38.61 ? 91 ASP A C 1 ATOM 642 O O . ASP A 1 91 ? 18.626 7.855 38.998 1.00 38.78 ? 91 ASP A O 1 ATOM 643 C CB . ASP A 1 91 ? 18.442 10.720 39.942 1.00 38.79 ? 91 ASP A CB 1 ATOM 644 C CG . ASP A 1 91 ? 17.071 11.427 40.121 1.00 40.03 ? 91 ASP A CG 1 ATOM 645 O OD1 . ASP A 1 91 ? 16.025 10.738 40.042 1.00 41.65 ? 91 ASP A OD1 1 ATOM 646 O OD2 . ASP A 1 91 ? 17.039 12.667 40.351 1.00 40.48 ? 91 ASP A OD2 1 ATOM 647 N N . ALA A 1 92 ? 17.094 8.638 37.531 1.00 39.11 ? 92 ALA A N 1 ATOM 648 C CA . ALA A 1 92 ? 16.241 7.432 37.442 1.00 39.17 ? 92 ALA A CA 1 ATOM 649 C C . ALA A 1 92 ? 16.982 6.100 37.366 1.00 39.13 ? 92 ALA A C 1 ATOM 650 O O . ALA A 1 92 ? 16.538 5.110 37.949 1.00 38.86 ? 92 ALA A O 1 ATOM 651 C CB . ALA A 1 92 ? 15.255 7.562 36.272 1.00 39.07 ? 92 ALA A CB 1 ATOM 652 N N . ILE A 1 93 ? 18.098 6.093 36.640 1.00 39.22 ? 93 ILE A N 1 ATOM 653 C CA . ILE A 1 93 ? 18.972 4.929 36.552 1.00 39.58 ? 93 ILE A CA 1 ATOM 654 C C . ILE A 1 93 ? 19.286 4.290 37.921 1.00 39.85 ? 93 ILE A C 1 ATOM 655 O O . ILE A 1 93 ? 18.862 3.161 38.185 1.00 39.87 ? 93 ILE A O 1 ATOM 656 C CB . ILE A 1 93 ? 20.273 5.250 35.785 1.00 39.70 ? 93 ILE A CB 1 ATOM 657 C CG1 . ILE A 1 93 ? 20.834 6.621 36.211 1.00 39.85 ? 93 ILE A CG1 1 ATOM 658 C CG2 . ILE A 1 93 ? 20.009 5.202 34.280 1.00 39.50 ? 93 ILE A CG2 1 ATOM 659 C CD1 . ILE A 1 93 ? 22.348 6.667 36.325 1.00 39.53 ? 93 ILE A CD1 1 ATOM 660 N N . SER A 1 94 ? 19.998 5.011 38.788 1.00 40.01 ? 94 SER A N 1 ATOM 661 C CA . SER A 1 94 ? 20.393 4.489 40.097 1.00 40.17 ? 94 SER A CA 1 ATOM 662 C C . SER A 1 94 ? 19.207 4.128 41.008 1.00 40.14 ? 94 SER A C 1 ATOM 663 O O . SER A 1 94 ? 19.324 3.233 41.844 1.00 40.28 ? 94 SER A O 1 ATOM 664 C CB . SER A 1 94 ? 21.330 5.466 40.810 1.00 40.26 ? 94 SER A CB 1 ATOM 665 O OG . SER A 1 94 ? 20.609 6.559 41.351 1.00 40.49 ? 94 SER A OG 1 ATOM 666 N N . LEU A 1 95 ? 18.069 4.797 40.839 1.00 39.95 ? 95 LEU A N 1 ATOM 667 C CA . LEU A 1 95 ? 16.867 4.477 41.641 1.00 40.09 ? 95 LEU A CA 1 ATOM 668 C C . LEU A 1 95 ? 15.959 3.325 41.138 1.00 40.00 ? 95 LEU A C 1 ATOM 669 O O . LEU A 1 95 ? 14.910 3.055 41.730 1.00 39.74 ? 95 LEU A O 1 ATOM 670 C CB . LEU A 1 95 ? 15.984 5.713 41.834 1.00 40.21 ? 95 LEU A CB 1 ATOM 671 C CG . LEU A 1 95 ? 16.547 7.115 41.956 1.00 40.22 ? 95 LEU A CG 1 ATOM 672 C CD1 . LEU A 1 95 ? 15.389 7.997 42.385 1.00 39.42 ? 95 LEU A CD1 1 ATOM 673 C CD2 . LEU A 1 95 ? 17.739 7.181 42.926 1.00 39.88 ? 95 LEU A CD2 1 ATOM 674 N N . GLY A 1 96 ? 16.332 2.669 40.044 1.00 40.04 ? 96 GLY A N 1 ATOM 675 C CA . GLY A 1 96 ? 15.580 1.507 39.572 1.00 39.67 ? 96 GLY A CA 1 ATOM 676 C C . GLY A 1 96 ? 14.436 1.826 38.630 1.00 39.42 ? 96 GLY A C 1 ATOM 677 O O . GLY A 1 96 ? 14.009 0.953 37.877 1.00 39.59 ? 96 GLY A O 1 ATOM 678 N N . LEU A 1 97 ? 13.950 3.070 38.661 1.00 38.98 ? 97 LEU A N 1 ATOM 679 C CA . LEU A 1 97 ? 12.831 3.513 37.805 1.00 38.57 ? 97 LEU A CA 1 ATOM 680 C C . LEU A 1 97 ? 13.241 3.535 36.320 1.00 38.52 ? 97 LEU A C 1 ATOM 681 O O . LEU A 1 97 ? 14.254 4.152 35.936 1.00 38.94 ? 97 LEU A O 1 ATOM 682 C CB . LEU A 1 97 ? 12.331 4.895 38.243 1.00 38.37 ? 97 LEU A CB 1 ATOM 683 C CG . LEU A 1 97 ? 12.136 5.103 39.750 1.00 37.99 ? 97 LEU A CG 1 ATOM 684 C CD1 . LEU A 1 97 ? 12.610 6.459 40.233 1.00 37.28 ? 97 LEU A CD1 1 ATOM 685 C CD2 . LEU A 1 97 ? 10.708 4.877 40.150 1.00 36.77 ? 97 LEU A CD2 1 ATOM 686 N N . GLY A 1 98 ? 12.465 2.851 35.486 1.00 37.67 ? 98 GLY A N 1 ATOM 687 C CA . GLY A 1 98 ? 12.818 2.703 34.082 1.00 36.18 ? 98 GLY A CA 1 ATOM 688 C C . GLY A 1 98 ? 11.603 2.233 33.324 1.00 35.50 ? 98 GLY A C 1 ATOM 689 O O . GLY A 1 98 ? 10.491 2.219 33.875 1.00 35.59 ? 98 GLY A O 1 ATOM 690 N N . LYS A 1 99 ? 11.821 1.814 32.077 1.00 34.65 ? 99 LYS A N 1 ATOM 691 C CA . LYS A 1 99 ? 10.740 1.555 31.114 1.00 33.63 ? 99 LYS A CA 1 ATOM 692 C C . LYS A 1 99 ? 9.733 0.525 31.586 1.00 32.97 ? 99 LYS A C 1 ATOM 693 O O . LYS A 1 99 ? 8.857 0.122 30.833 1.00 32.94 ? 99 LYS A O 1 ATOM 694 C CB . LYS A 1 99 ? 11.302 1.194 29.725 1.00 33.95 ? 99 LYS A CB 1 ATOM 695 C CG . LYS A 1 99 ? 11.717 2.424 28.836 1.00 33.37 ? 99 LYS A CG 1 ATOM 696 C CD . LYS A 1 99 ? 12.343 1.961 27.526 1.00 32.72 ? 99 LYS A CD 1 ATOM 697 C CE . LYS A 1 99 ? 13.452 2.882 27.043 1.00 32.58 ? 99 LYS A CE 1 ATOM 698 N NZ . LYS A 1 99 ? 12.977 3.977 26.160 1.00 32.89 ? 99 LYS A NZ 1 ATOM 699 N N . HIS A 1 100 ? 9.832 0.145 32.858 1.00 32.29 ? 100 HIS A N 1 ATOM 700 C CA . HIS A 1 100 ? 8.959 -0.867 33.430 1.00 31.21 ? 100 HIS A CA 1 ATOM 701 C C . HIS A 1 100 ? 7.893 -0.288 34.287 1.00 31.01 ? 100 HIS A C 1 ATOM 702 O O . HIS A 1 100 ? 7.631 0.909 34.263 1.00 30.54 ? 100 HIS A O 1 ATOM 703 C CB . HIS A 1 100 ? 9.725 -1.865 34.266 1.00 30.83 ? 100 HIS A CB 1 ATOM 704 C CG . HIS A 1 100 ? 10.482 -1.239 35.386 1.00 29.70 ? 100 HIS A CG 1 ATOM 705 N ND1 . HIS A 1 100 ? 11.836 -0.992 35.321 1.00 29.50 ? 100 HIS A ND1 1 ATOM 706 C CD2 . HIS A 1 100 ? 10.078 -0.799 36.594 1.00 29.17 ? 100 HIS A CD2 1 ATOM 707 C CE1 . HIS A 1 100 ? 12.233 -0.423 36.440 1.00 28.19 ? 100 HIS A CE1 1 ATOM 708 N NE2 . HIS A 1 100 ? 11.186 -0.299 37.232 1.00 28.93 ? 100 HIS A NE2 1 ATOM 709 N N . ASN A 1 101 ? 7.328 -1.190 35.076 1.00 31.26 ? 101 ASN A N 1 ATOM 710 C CA . ASN A 1 101 ? 6.003 -1.092 35.623 1.00 31.62 ? 101 ASN A CA 1 ATOM 711 C C . ASN A 1 101 ? 6.091 -1.590 37.021 1.00 31.73 ? 101 ASN A C 1 ATOM 712 O O . ASN A 1 101 ? 5.085 -1.842 37.678 1.00 31.72 ? 101 ASN A O 1 ATOM 713 C CB . ASN A 1 101 ? 5.092 -2.045 34.856 1.00 31.87 ? 101 ASN A CB 1 ATOM 714 C CG . ASN A 1 101 ? 3.703 -2.099 35.438 1.00 33.69 ? 101 ASN A CG 1 ATOM 715 O OD1 . ASN A 1 101 ? 3.145 -1.064 35.808 1.00 35.52 ? 101 ASN A OD1 1 ATOM 716 N ND2 . ASN A 1 101 ? 3.144 -3.303 35.559 1.00 34.50 ? 101 ASN A ND2 1 ATOM 717 N N . TYR A 1 102 ? 7.316 -1.753 37.488 1.00 32.39 ? 102 TYR A N 1 ATOM 718 C CA . TYR A 1 102 ? 7.523 -2.489 38.720 1.00 32.88 ? 102 TYR A CA 1 ATOM 719 C C . TYR A 1 102 ? 7.306 -1.653 39.948 1.00 33.69 ? 102 TYR A C 1 ATOM 720 O O . TYR A 1 102 ? 6.611 -0.624 39.909 1.00 34.49 ? 102 TYR A O 1 ATOM 721 C CB . TYR A 1 102 ? 8.869 -3.204 38.725 1.00 32.29 ? 102 TYR A CB 1 ATOM 722 C CG . TYR A 1 102 ? 8.959 -4.121 37.540 1.00 31.75 ? 102 TYR A CG 1 ATOM 723 C CD1 . TYR A 1 102 ? 7.854 -4.896 37.161 1.00 31.04 ? 102 TYR A CD1 1 ATOM 724 C CD2 . TYR A 1 102 ? 10.114 -4.198 36.778 1.00 30.40 ? 102 TYR A CD2 1 ATOM 725 C CE1 . TYR A 1 102 ? 7.901 -5.719 36.068 1.00 30.20 ? 102 TYR A CE1 1 ATOM 726 C CE2 . TYR A 1 102 ? 10.171 -5.021 35.684 1.00 30.63 ? 102 TYR A CE2 1 ATOM 727 C CZ . TYR A 1 102 ? 9.058 -5.781 35.334 1.00 30.98 ? 102 TYR A CZ 1 ATOM 728 O OH . TYR A 1 102 ? 9.116 -6.621 34.247 1.00 32.69 ? 102 TYR A OH 1 ATOM 729 N N . CYS A 1 103 ? 7.846 -2.115 41.058 1.00 33.72 ? 103 CYS A N 1 ATOM 730 C CA . CYS A 1 103 ? 7.679 -1.393 42.265 1.00 33.75 ? 103 CYS A CA 1 ATOM 731 C C . CYS A 1 103 ? 8.976 -0.902 42.679 1.00 33.08 ? 103 CYS A C 1 ATOM 732 O O . CYS A 1 103 ? 9.989 -1.544 42.475 1.00 32.98 ? 103 CYS A O 1 ATOM 733 C CB . CYS A 1 103 ? 7.066 -2.253 43.305 1.00 34.01 ? 103 CYS A CB 1 ATOM 734 S SG . CYS A 1 103 ? 5.381 -1.949 43.055 1.00 39.61 ? 103 CYS A SG 1 ATOM 735 N N . ARG A 1 104 ? 8.957 0.296 43.206 1.00 32.71 ? 104 ARG A N 1 ATOM 736 C CA . ARG A 1 104 ? 10.175 0.853 43.680 1.00 32.67 ? 104 ARG A CA 1 ATOM 737 C C . ARG A 1 104 ? 9.785 1.596 44.925 1.00 32.39 ? 104 ARG A C 1 ATOM 738 O O . ARG A 1 104 ? 8.601 1.611 45.288 1.00 32.06 ? 104 ARG A O 1 ATOM 739 C CB . ARG A 1 104 ? 10.831 1.737 42.606 1.00 32.48 ? 104 ARG A CB 1 ATOM 740 C CG . ARG A 1 104 ? 11.276 0.985 41.343 1.00 33.01 ? 104 ARG A CG 1 ATOM 741 C CD . ARG A 1 104 ? 12.366 -0.036 41.627 1.00 35.93 ? 104 ARG A CD 1 ATOM 742 N NE . ARG A 1 104 ? 12.852 -0.757 40.443 1.00 38.56 ? 104 ARG A NE 1 ATOM 743 C CZ . ARG A 1 104 ? 12.619 -2.051 40.189 1.00 40.24 ? 104 ARG A CZ 1 ATOM 744 N NH1 . ARG A 1 104 ? 11.892 -2.781 41.026 1.00 41.48 ? 104 ARG A NH1 1 ATOM 745 N NH2 . ARG A 1 104 ? 13.117 -2.630 39.100 1.00 39.52 ? 104 ARG A NH2 1 ATOM 746 N N . ASN A 1 105 ? 10.790 2.164 45.583 1.00 32.04 ? 105 ASN A N 1 ATOM 747 C CA . ASN A 1 105 ? 10.598 3.026 46.708 1.00 31.76 ? 105 ASN A CA 1 ATOM 748 C C . ASN A 1 105 ? 11.813 3.913 46.765 1.00 31.88 ? 105 ASN A C 1 ATOM 749 O O . ASN A 1 105 ? 12.667 3.708 47.617 1.00 31.94 ? 105 ASN A O 1 ATOM 750 C CB . ASN A 1 105 ? 10.511 2.179 47.954 1.00 31.88 ? 105 ASN A CB 1 ATOM 751 C CG . ASN A 1 105 ? 10.447 2.992 49.197 1.00 31.92 ? 105 ASN A CG 1 ATOM 752 O OD1 . ASN A 1 105 ? 10.027 4.140 49.178 1.00 32.11 ? 105 ASN A OD1 1 ATOM 753 N ND2 . ASN A 1 105 ? 10.879 2.404 50.300 1.00 32.88 ? 105 ASN A ND2 1 ATOM 754 N N . PRO A 1 106 ? 11.905 4.893 45.840 1.00 32.08 ? 106 PRO A N 1 ATOM 755 C CA . PRO A 1 106 ? 13.097 5.752 45.611 1.00 32.13 ? 106 PRO A CA 1 ATOM 756 C C . PRO A 1 106 ? 13.315 6.838 46.677 1.00 32.22 ? 106 PRO A C 1 ATOM 757 O O . PRO A 1 106 ? 14.438 6.996 47.181 1.00 32.52 ? 106 PRO A O 1 ATOM 758 C CB . PRO A 1 106 ? 12.833 6.389 44.237 1.00 32.15 ? 106 PRO A CB 1 ATOM 759 C CG . PRO A 1 106 ? 11.455 5.891 43.792 1.00 32.09 ? 106 PRO A CG 1 ATOM 760 C CD . PRO A 1 106 ? 10.778 5.280 44.975 1.00 31.96 ? 106 PRO A CD 1 ATOM 761 N N . ASP A 1 107 ? 12.259 7.579 47.011 1.00 31.96 ? 107 ASP A N 1 ATOM 762 C CA . ASP A 1 107 ? 12.251 8.412 48.206 1.00 31.81 ? 107 ASP A CA 1 ATOM 763 C C . ASP A 1 107 ? 12.163 7.462 49.402 1.00 32.06 ? 107 ASP A C 1 ATOM 764 O O . ASP A 1 107 ? 12.359 6.252 49.255 1.00 32.26 ? 107 ASP A O 1 ATOM 765 C CB . ASP A 1 107 ? 11.042 9.337 48.178 1.00 31.51 ? 107 ASP A CB 1 ATOM 766 C CG . ASP A 1 107 ? 9.746 8.588 47.979 1.00 30.54 ? 107 ASP A CG 1 ATOM 767 O OD1 . ASP A 1 107 ? 8.670 9.208 48.130 1.00 30.21 ? 107 ASP A OD1 1 ATOM 768 O OD2 . ASP A 1 107 ? 9.800 7.379 47.675 1.00 28.77 ? 107 ASP A OD2 1 ATOM 769 N N . ASN A 1 108 ? 11.871 7.989 50.583 1.00 32.08 ? 108 ASN A N 1 ATOM 770 C CA . ASN A 1 108 ? 11.543 7.103 51.684 1.00 32.28 ? 108 ASN A CA 1 ATOM 771 C C . ASN A 1 108 ? 10.101 6.687 51.639 1.00 32.11 ? 108 ASN A C 1 ATOM 772 O O . ASN A 1 108 ? 9.310 7.287 50.920 1.00 31.91 ? 108 ASN A O 1 ATOM 773 C CB . ASN A 1 108 ? 11.889 7.717 53.023 1.00 32.58 ? 108 ASN A CB 1 ATOM 774 C CG . ASN A 1 108 ? 13.290 7.391 53.434 1.00 33.91 ? 108 ASN A CG 1 ATOM 775 O OD1 . ASN A 1 108 ? 13.995 6.655 52.719 1.00 34.89 ? 108 ASN A OD1 1 ATOM 776 N ND2 . ASN A 1 108 ? 13.721 7.924 54.585 1.00 34.32 ? 108 ASN A ND2 1 ATOM 777 N N . GLN A 1 109 ? 9.779 5.640 52.392 1.00 32.06 ? 109 GLN A N 1 ATOM 778 C CA . GLN A 1 109 ? 8.440 5.048 52.441 1.00 31.89 ? 109 GLN A CA 1 ATOM 779 C C . GLN A 1 109 ? 8.533 3.622 52.971 1.00 31.34 ? 109 GLN A C 1 ATOM 780 O O . GLN A 1 109 ? 9.322 2.822 52.466 1.00 31.53 ? 109 GLN A O 1 ATOM 781 C CB . GLN A 1 109 ? 7.763 5.047 51.063 1.00 31.97 ? 109 GLN A CB 1 ATOM 782 C CG . GLN A 1 109 ? 6.925 6.282 50.756 1.00 33.34 ? 109 GLN A CG 1 ATOM 783 C CD . GLN A 1 109 ? 5.616 6.327 51.536 1.00 36.49 ? 109 GLN A CD 1 ATOM 784 O OE1 . GLN A 1 109 ? 4.536 6.308 50.932 1.00 38.35 ? 109 GLN A OE1 1 ATOM 785 N NE2 . GLN A 1 109 ? 5.699 6.380 52.880 1.00 35.61 ? 109 GLN A NE2 1 ATOM 786 N N . LYS A 1 110 ? 7.733 3.311 53.987 1.00 30.49 ? 110 LYS A N 1 ATOM 787 C CA . LYS A 1 110 ? 7.711 1.973 54.578 1.00 29.50 ? 110 LYS A CA 1 ATOM 788 C C . LYS A 1 110 ? 8.172 0.890 53.590 1.00 28.93 ? 110 LYS A C 1 ATOM 789 O O . LYS A 1 110 ? 9.263 0.369 53.751 1.00 28.76 ? 110 LYS A O 1 ATOM 790 C CB . LYS A 1 110 ? 6.350 1.673 55.232 1.00 29.30 ? 110 LYS A CB 1 ATOM 791 C CG . LYS A 1 110 ? 5.131 2.356 54.585 1.00 29.72 ? 110 LYS A CG 1 ATOM 792 C CD . LYS A 1 110 ? 5.118 3.894 54.735 1.00 29.44 ? 110 LYS A CD 1 ATOM 793 C CE . LYS A 1 110 ? 4.431 4.373 56.019 1.00 29.83 ? 110 LYS A CE 1 ATOM 794 N NZ . LYS A 1 110 ? 5.205 4.086 57.257 1.00 28.51 ? 110 LYS A NZ 1 ATOM 795 N N . ARG A 1 111 ? 7.384 0.620 52.544 1.00 28.57 ? 111 ARG A N 1 ATOM 796 C CA . ARG A 1 111 ? 7.676 -0.424 51.538 1.00 28.11 ? 111 ARG A CA 1 ATOM 797 C C . ARG A 1 111 ? 7.716 0.123 50.108 1.00 27.71 ? 111 ARG A C 1 ATOM 798 O O . ARG A 1 111 ? 7.660 1.330 49.940 1.00 27.34 ? 111 ARG A O 1 ATOM 799 C CB . ARG A 1 111 ? 6.626 -1.518 51.624 1.00 28.25 ? 111 ARG A CB 1 ATOM 800 C CG . ARG A 1 111 ? 5.209 -1.014 51.493 1.00 29.61 ? 111 ARG A CG 1 ATOM 801 C CD . ARG A 1 111 ? 4.370 -1.970 50.654 1.00 32.29 ? 111 ARG A CD 1 ATOM 802 N NE . ARG A 1 111 ? 4.104 -3.310 51.216 1.00 33.59 ? 111 ARG A NE 1 ATOM 803 C CZ . ARG A 1 111 ? 4.030 -3.644 52.511 1.00 33.71 ? 111 ARG A CZ 1 ATOM 804 N NH1 . ARG A 1 111 ? 4.215 -2.743 53.483 1.00 32.46 ? 111 ARG A NH1 1 ATOM 805 N NH2 . ARG A 1 111 ? 3.762 -4.909 52.832 1.00 32.93 ? 111 ARG A NH2 1 ATOM 806 N N . PRO A 1 112 ? 7.835 -0.755 49.069 1.00 27.75 ? 112 PRO A N 1 ATOM 807 C CA . PRO A 1 112 ? 7.764 -0.212 47.710 1.00 27.70 ? 112 PRO A CA 1 ATOM 808 C C . PRO A 1 112 ? 6.351 -0.030 47.233 1.00 28.08 ? 112 PRO A C 1 ATOM 809 O O . PRO A 1 112 ? 5.450 -0.765 47.637 1.00 28.19 ? 112 PRO A O 1 ATOM 810 C CB . PRO A 1 112 ? 8.482 -1.258 46.854 1.00 27.09 ? 112 PRO A CB 1 ATOM 811 C CG . PRO A 1 112 ? 9.294 -2.050 47.807 1.00 26.99 ? 112 PRO A CG 1 ATOM 812 C CD . PRO A 1 112 ? 8.403 -2.113 49.023 1.00 27.91 ? 112 PRO A CD 1 ATOM 813 N N . TRP A 1 113 ? 6.187 0.957 46.359 1.00 28.75 ? 113 TRP A N 1 ATOM 814 C CA . TRP A 1 113 ? 4.885 1.449 45.923 1.00 29.01 ? 113 TRP A CA 1 ATOM 815 C C . TRP A 1 113 ? 4.932 1.704 44.428 1.00 29.40 ? 113 TRP A C 1 ATOM 816 O O . TRP A 1 113 ? 5.978 1.499 43.781 1.00 29.48 ? 113 TRP A O 1 ATOM 817 C CB . TRP A 1 113 ? 4.604 2.761 46.630 1.00 28.76 ? 113 TRP A CB 1 ATOM 818 C CG . TRP A 1 113 ? 5.757 3.720 46.514 1.00 29.02 ? 113 TRP A CG 1 ATOM 819 C CD1 . TRP A 1 113 ? 6.817 3.853 47.374 1.00 29.11 ? 113 TRP A CD1 1 ATOM 820 C CD2 . TRP A 1 113 ? 5.977 4.663 45.466 1.00 29.78 ? 113 TRP A CD2 1 ATOM 821 N NE1 . TRP A 1 113 ? 7.681 4.825 46.928 1.00 29.00 ? 113 TRP A NE1 1 ATOM 822 C CE2 . TRP A 1 113 ? 7.191 5.343 45.761 1.00 29.46 ? 113 TRP A CE2 1 ATOM 823 C CE3 . TRP A 1 113 ? 5.265 5.011 44.310 1.00 29.10 ? 113 TRP A CE3 1 ATOM 824 C CZ2 . TRP A 1 113 ? 7.704 6.343 44.942 1.00 29.22 ? 113 TRP A CZ2 1 ATOM 825 C CZ3 . TRP A 1 113 ? 5.771 5.998 43.500 1.00 29.67 ? 113 TRP A CZ3 1 ATOM 826 C CH2 . TRP A 1 113 ? 6.983 6.661 43.819 1.00 30.24 ? 113 TRP A CH2 1 ATOM 827 N N . CYS A 1 114 ? 3.809 2.170 43.886 1.00 29.76 ? 114 CYS A N 1 ATOM 828 C CA . CYS A 1 114 ? 3.757 2.605 42.493 1.00 30.24 ? 114 CYS A CA 1 ATOM 829 C C . CYS A 1 114 ? 2.500 3.374 42.215 1.00 29.38 ? 114 CYS A C 1 ATOM 830 O O . CYS A 1 114 ? 1.503 3.222 42.900 1.00 28.64 ? 114 CYS A O 1 ATOM 831 C CB . CYS A 1 114 ? 3.812 1.409 41.549 1.00 30.79 ? 114 CYS A CB 1 ATOM 832 S SG . CYS A 1 114 ? 2.362 0.336 41.750 1.00 33.83 ? 114 CYS A SG 1 ATOM 833 N N . TYR A 1 115 ? 2.559 4.167 41.159 1.00 29.53 ? 115 TYR A N 1 ATOM 834 C CA . TYR A 1 115 ? 1.461 5.038 40.787 1.00 29.83 ? 115 TYR A CA 1 ATOM 835 C C . TYR A 1 115 ? 0.344 4.262 40.106 1.00 30.16 ? 115 TYR A C 1 ATOM 836 O O . TYR A 1 115 ? 0.536 3.634 39.060 1.00 30.15 ? 115 TYR A O 1 ATOM 837 C CB . TYR A 1 115 ? 1.971 6.172 39.910 1.00 29.41 ? 115 TYR A CB 1 ATOM 838 C CG . TYR A 1 115 ? 2.845 7.155 40.653 1.00 29.15 ? 115 TYR A CG 1 ATOM 839 C CD1 . TYR A 1 115 ? 2.360 7.870 41.776 1.00 29.23 ? 115 TYR A CD1 1 ATOM 840 C CD2 . TYR A 1 115 ? 4.157 7.391 40.237 1.00 28.38 ? 115 TYR A CD2 1 ATOM 841 C CE1 . TYR A 1 115 ? 3.183 8.798 42.453 1.00 29.21 ? 115 TYR A CE1 1 ATOM 842 C CE2 . TYR A 1 115 ? 4.986 8.312 40.905 1.00 28.73 ? 115 TYR A CE2 1 ATOM 843 C CZ . TYR A 1 115 ? 4.497 9.010 42.001 1.00 29.52 ? 115 TYR A CZ 1 ATOM 844 O OH . TYR A 1 115 ? 5.340 9.904 42.632 1.00 31.03 ? 115 TYR A OH 1 ATOM 845 N N . VAL A 1 116 ? -0.824 4.308 40.721 1.00 30.36 ? 116 VAL A N 1 ATOM 846 C CA . VAL A 1 116 ? -1.888 3.412 40.354 1.00 30.86 ? 116 VAL A CA 1 ATOM 847 C C . VAL A 1 116 ? -3.041 4.221 39.853 1.00 31.15 ? 116 VAL A C 1 ATOM 848 O O . VAL A 1 116 ? -3.384 5.232 40.447 1.00 31.35 ? 116 VAL A O 1 ATOM 849 C CB . VAL A 1 116 ? -2.313 2.581 41.577 1.00 31.00 ? 116 VAL A CB 1 ATOM 850 C CG1 . VAL A 1 116 ? -3.684 1.915 41.363 1.00 31.13 ? 116 VAL A CG1 1 ATOM 851 C CG2 . VAL A 1 116 ? -1.230 1.552 41.907 1.00 30.60 ? 116 VAL A CG2 1 ATOM 852 N N . GLN A 1 117 ? -3.629 3.791 38.748 1.00 31.49 ? 117 GLN A N 1 ATOM 853 C CA . GLN A 1 117 ? -4.797 4.474 38.226 1.00 32.00 ? 117 GLN A CA 1 ATOM 854 C C . GLN A 1 117 ? -5.996 3.977 39.029 1.00 32.46 ? 117 GLN A C 1 ATOM 855 O O . GLN A 1 117 ? -6.096 2.784 39.294 1.00 33.13 ? 117 GLN A O 1 ATOM 856 C CB . GLN A 1 117 ? -4.949 4.145 36.745 1.00 31.77 ? 117 GLN A CB 1 ATOM 857 C CG . GLN A 1 117 ? -6.248 4.618 36.126 1.00 32.12 ? 117 GLN A CG 1 ATOM 858 C CD . GLN A 1 117 ? -6.178 6.042 35.638 1.00 32.65 ? 117 GLN A CD 1 ATOM 859 O OE1 . GLN A 1 117 ? -5.144 6.481 35.107 1.00 32.44 ? 117 GLN A OE1 1 ATOM 860 N NE2 . GLN A 1 117 ? -7.282 6.779 35.803 1.00 31.08 ? 117 GLN A NE2 1 ATOM 861 N N . ILE A 1 118 ? -6.875 4.878 39.457 1.00 32.62 ? 118 ILE A N 1 ATOM 862 C CA . ILE A 1 118 ? -8.133 4.495 40.125 1.00 32.91 ? 118 ILE A CA 1 ATOM 863 C C . ILE A 1 118 ? -9.147 5.564 39.779 1.00 33.17 ? 118 ILE A C 1 ATOM 864 O O . ILE A 1 118 ? -8.956 6.737 40.112 1.00 33.27 ? 118 ILE A O 1 ATOM 865 C CB . ILE A 1 118 ? -8.008 4.279 41.685 1.00 33.04 ? 118 ILE A CB 1 ATOM 866 C CG1 . ILE A 1 118 ? -9.299 4.668 42.436 1.00 33.65 ? 118 ILE A CG1 1 ATOM 867 C CG2 . ILE A 1 118 ? -6.852 5.073 42.290 1.00 33.16 ? 118 ILE A CG2 1 ATOM 868 C CD1 . ILE A 1 118 ? -10.425 3.618 42.444 1.00 34.62 ? 118 ILE A CD1 1 ATOM 869 N N . GLY A 1 119 ? -10.223 5.154 39.107 1.00 33.42 ? 119 GLY A N 1 ATOM 870 C CA . GLY A 1 119 ? -11.068 6.094 38.386 1.00 33.44 ? 119 GLY A CA 1 ATOM 871 C C . GLY A 1 119 ? -10.185 6.944 37.481 1.00 33.63 ? 119 GLY A C 1 ATOM 872 O O . GLY A 1 119 ? -9.464 6.419 36.625 1.00 33.30 ? 119 GLY A O 1 ATOM 873 N N . LEU A 1 120 ? -10.199 8.254 37.716 1.00 33.83 ? 120 LEU A N 1 ATOM 874 C CA . LEU A 1 120 ? -9.499 9.205 36.856 1.00 33.93 ? 120 LEU A CA 1 ATOM 875 C C . LEU A 1 120 ? -8.073 9.528 37.305 1.00 34.03 ? 120 LEU A C 1 ATOM 876 O O . LEU A 1 120 ? -7.176 9.601 36.474 1.00 34.07 ? 120 LEU A O 1 ATOM 877 C CB . LEU A 1 120 ? -10.316 10.492 36.725 1.00 33.88 ? 120 LEU A CB 1 ATOM 878 C CG . LEU A 1 120 ? -10.319 11.194 35.363 1.00 33.59 ? 120 LEU A CG 1 ATOM 879 C CD1 . LEU A 1 120 ? -11.600 11.975 35.220 1.00 32.68 ? 120 LEU A CD1 1 ATOM 880 C CD2 . LEU A 1 120 ? -9.103 12.102 35.167 1.00 33.29 ? 120 LEU A CD2 1 ATOM 881 N N . ARG A 1 121 ? -7.877 9.726 38.607 1.00 34.26 ? 121 ARG A N 1 ATOM 882 C CA . ARG A 1 121 ? -6.594 10.170 39.166 1.00 34.54 ? 121 ARG A CA 1 ATOM 883 C C . ARG A 1 121 ? -5.467 9.136 39.195 1.00 34.87 ? 121 ARG A C 1 ATOM 884 O O . ARG A 1 121 ? -5.652 7.958 38.861 1.00 34.93 ? 121 ARG A O 1 ATOM 885 C CB . ARG A 1 121 ? -6.800 10.661 40.591 1.00 34.55 ? 121 ARG A CB 1 ATOM 886 C CG . ARG A 1 121 ? -7.042 12.131 40.723 1.00 34.62 ? 121 ARG A CG 1 ATOM 887 C CD . ARG A 1 121 ? -6.897 12.520 42.174 1.00 34.98 ? 121 ARG A CD 1 ATOM 888 N NE . ARG A 1 121 ? -7.406 13.861 42.442 1.00 35.73 ? 121 ARG A NE 1 ATOM 889 C CZ . ARG A 1 121 ? -7.414 14.446 43.640 1.00 35.80 ? 121 ARG A CZ 1 ATOM 890 N NH1 . ARG A 1 121 ? -6.935 13.810 44.707 1.00 35.62 ? 121 ARG A NH1 1 ATOM 891 N NH2 . ARG A 1 121 ? -7.903 15.677 43.771 1.00 35.93 ? 121 ARG A NH2 1 ATOM 892 N N . GLN A 1 122 ? -4.292 9.599 39.611 1.00 35.16 ? 122 GLN A N 1 ATOM 893 C CA . GLN A 1 122 ? -3.157 8.715 39.841 1.00 35.53 ? 122 GLN A CA 1 ATOM 894 C C . GLN A 1 122 ? -2.698 8.710 41.281 1.00 35.52 ? 122 GLN A C 1 ATOM 895 O O . GLN A 1 122 ? -1.712 9.366 41.633 1.00 35.52 ? 122 GLN A O 1 ATOM 896 C CB . GLN A 1 122 ? -1.975 9.069 38.944 1.00 35.63 ? 122 GLN A CB 1 ATOM 897 C CG . GLN A 1 122 ? -1.970 8.315 37.645 1.00 36.38 ? 122 GLN A CG 1 ATOM 898 C CD . GLN A 1 122 ? -2.743 9.031 36.559 1.00 36.82 ? 122 GLN A CD 1 ATOM 899 O OE1 . GLN A 1 122 ? -3.953 9.260 36.673 1.00 36.41 ? 122 GLN A OE1 1 ATOM 900 N NE2 . GLN A 1 122 ? -2.039 9.394 35.491 1.00 36.50 ? 122 GLN A NE2 1 ATOM 901 N N . PHE A 1 123 ? -3.412 7.951 42.101 1.00 35.59 ? 123 PHE A N 1 ATOM 902 C CA . PHE A 1 123 ? -2.975 7.644 43.455 1.00 35.74 ? 123 PHE A CA 1 ATOM 903 C C . PHE A 1 123 ? -1.674 6.807 43.497 1.00 35.56 ? 123 PHE A C 1 ATOM 904 O O . PHE A 1 123 ? -1.398 5.992 42.612 1.00 35.23 ? 123 PHE A O 1 ATOM 905 C CB . PHE A 1 123 ? -4.109 6.956 44.223 1.00 35.75 ? 123 PHE A CB 1 ATOM 906 C CG . PHE A 1 123 ? -5.243 7.875 44.590 1.00 36.36 ? 123 PHE A CG 1 ATOM 907 C CD1 . PHE A 1 123 ? -6.049 8.446 43.608 1.00 36.53 ? 123 PHE A CD1 1 ATOM 908 C CD2 . PHE A 1 123 ? -5.514 8.161 45.932 1.00 37.46 ? 123 PHE A CD2 1 ATOM 909 C CE1 . PHE A 1 123 ? -7.107 9.295 43.959 1.00 37.64 ? 123 PHE A CE1 1 ATOM 910 C CE2 . PHE A 1 123 ? -6.575 9.012 46.301 1.00 37.65 ? 123 PHE A CE2 1 ATOM 911 C CZ . PHE A 1 123 ? -7.371 9.581 45.314 1.00 37.70 ? 123 PHE A CZ 1 ATOM 912 N N . VAL A 1 124 ? -0.872 7.056 44.523 1.00 35.68 ? 124 VAL A N 1 ATOM 913 C CA . VAL A 1 124 ? 0.304 6.260 44.797 1.00 36.15 ? 124 VAL A CA 1 ATOM 914 C C . VAL A 1 124 ? -0.082 5.177 45.778 1.00 36.77 ? 124 VAL A C 1 ATOM 915 O O . VAL A 1 124 ? -0.350 5.449 46.945 1.00 36.86 ? 124 VAL A O 1 ATOM 916 C CB . VAL A 1 124 ? 1.441 7.098 45.393 1.00 36.19 ? 124 VAL A CB 1 ATOM 917 C CG1 . VAL A 1 124 ? 0.877 8.203 46.290 1.00 36.53 ? 124 VAL A CG1 1 ATOM 918 C CG2 . VAL A 1 124 ? 2.450 6.213 46.146 1.00 34.73 ? 124 VAL A CG2 1 ATOM 919 N N . GLN A 1 125 ? -0.110 3.944 45.291 1.00 37.67 ? 125 GLN A N 1 ATOM 920 C CA . GLN A 1 125 ? -0.499 2.806 46.106 1.00 38.39 ? 125 GLN A CA 1 ATOM 921 C C . GLN A 1 125 ? 0.680 1.903 46.409 1.00 39.26 ? 125 GLN A C 1 ATOM 922 O O . GLN A 1 125 ? 1.733 1.998 45.773 1.00 39.07 ? 125 GLN A O 1 ATOM 923 C CB . GLN A 1 125 ? -1.612 2.023 45.431 1.00 38.07 ? 125 GLN A CB 1 ATOM 924 C CG . GLN A 1 125 ? -2.866 2.814 45.261 1.00 38.00 ? 125 GLN A CG 1 ATOM 925 C CD . GLN A 1 125 ? -3.716 2.812 46.497 1.00 38.51 ? 125 GLN A CD 1 ATOM 926 O OE1 . GLN A 1 125 ? -4.513 1.895 46.698 1.00 39.20 ? 125 GLN A OE1 1 ATOM 927 N NE2 . GLN A 1 125 ? -3.569 3.847 47.336 1.00 38.67 ? 125 GLN A NE2 1 ATOM 928 N N . GLU A 1 126 ? 0.476 1.030 47.393 1.00 40.64 ? 126 GLU A N 1 ATOM 929 C CA . GLU A 1 126 ? 1.521 0.161 47.922 1.00 42.13 ? 126 GLU A CA 1 ATOM 930 C C . GLU A 1 126 ? 1.565 -1.223 47.254 1.00 42.62 ? 126 GLU A C 1 ATOM 931 O O . GLU A 1 126 ? 0.540 -1.908 47.142 1.00 43.02 ? 126 GLU A O 1 ATOM 932 C CB . GLU A 1 126 ? 1.313 -0.042 49.412 1.00 42.12 ? 126 GLU A CB 1 ATOM 933 C CG . GLU A 1 126 ? 1.002 1.184 50.198 1.00 43.70 ? 126 GLU A CG 1 ATOM 934 C CD . GLU A 1 126 ? 0.952 0.849 51.671 1.00 46.98 ? 126 GLU A CD 1 ATOM 935 O OE1 . GLU A 1 126 ? -0.054 1.204 52.352 1.00 46.98 ? 126 GLU A OE1 1 ATOM 936 O OE2 . GLU A 1 126 ? 1.925 0.190 52.128 1.00 47.86 ? 126 GLU A OE2 1 ATOM 937 N N . CYS A 1 127 ? 2.763 -1.642 46.864 1.00 42.82 ? 127 CYS A N 1 ATOM 938 C CA . CYS A 1 127 ? 2.947 -2.893 46.177 1.00 43.53 ? 127 CYS A CA 1 ATOM 939 C C . CYS A 1 127 ? 2.677 -4.134 47.040 1.00 44.29 ? 127 CYS A C 1 ATOM 940 O O . CYS A 1 127 ? 2.369 -4.020 48.225 1.00 44.34 ? 127 CYS A O 1 ATOM 941 C CB . CYS A 1 127 ? 4.364 -2.935 45.673 1.00 43.25 ? 127 CYS A CB 1 ATOM 942 S SG . CYS A 1 127 ? 4.449 -3.504 44.000 1.00 44.14 ? 127 CYS A SG 1 ATOM 943 N N . MET A 1 128 ? 2.800 -5.321 46.442 1.00 45.21 ? 128 MET A N 1 ATOM 944 C CA . MET A 1 128 ? 2.629 -6.565 47.185 1.00 46.10 ? 128 MET A CA 1 ATOM 945 C C . MET A 1 128 ? 3.864 -7.176 47.800 1.00 46.09 ? 128 MET A C 1 ATOM 946 O O . MET A 1 128 ? 3.859 -7.479 48.992 1.00 46.50 ? 128 MET A O 1 ATOM 947 C CB . MET A 1 128 ? 1.955 -7.639 46.356 1.00 46.60 ? 128 MET A CB 1 ATOM 948 C CG . MET A 1 128 ? 0.617 -7.977 46.932 1.00 48.74 ? 128 MET A CG 1 ATOM 949 S SD . MET A 1 128 ? -0.363 -6.584 46.445 1.00 52.51 ? 128 MET A SD 1 ATOM 950 C CE . MET A 1 128 ? -0.183 -6.838 44.691 1.00 53.33 ? 128 MET A CE 1 ATOM 951 N N . VAL A 1 129 ? 4.881 -7.424 46.980 1.00 45.64 ? 129 VAL A N 1 ATOM 952 C CA . VAL A 1 129 ? 6.131 -8.024 47.440 1.00 45.46 ? 129 VAL A CA 1 ATOM 953 C C . VAL A 1 129 ? 6.202 -8.320 48.949 1.00 45.50 ? 129 VAL A C 1 ATOM 954 O O . VAL A 1 129 ? 6.323 -7.402 49.756 1.00 45.65 ? 129 VAL A O 1 ATOM 955 C CB . VAL A 1 129 ? 7.313 -7.116 47.080 1.00 45.43 ? 129 VAL A CB 1 ATOM 956 C CG1 . VAL A 1 129 ? 8.050 -7.642 45.881 1.00 45.24 ? 129 VAL A CG1 1 ATOM 957 C CG2 . VAL A 1 129 ? 6.824 -5.716 46.831 1.00 45.96 ? 129 VAL A CG2 1 ATOM 958 N N . HIS A 1 130 ? 6.143 -9.595 49.334 1.00 45.49 ? 130 HIS A N 1 ATOM 959 C CA . HIS A 1 130 ? 6.256 -9.947 50.740 1.00 45.30 ? 130 HIS A CA 1 ATOM 960 C C . HIS A 1 130 ? 7.624 -9.562 51.236 1.00 45.28 ? 130 HIS A C 1 ATOM 961 O O . HIS A 1 130 ? 8.602 -9.606 50.504 1.00 44.69 ? 130 HIS A O 1 ATOM 962 C CB . HIS A 1 130 ? 6.023 -11.436 50.976 1.00 45.40 ? 130 HIS A CB 1 ATOM 963 C CG . HIS A 1 130 ? 5.502 -11.773 52.351 1.00 46.08 ? 130 HIS A CG 1 ATOM 964 N ND1 . HIS A 1 130 ? 6.085 -12.731 53.160 1.00 45.13 ? 130 HIS A ND1 1 ATOM 965 C CD2 . HIS A 1 130 ? 4.429 -11.306 53.042 1.00 45.72 ? 130 HIS A CD2 1 ATOM 966 C CE1 . HIS A 1 130 ? 5.395 -12.839 54.283 1.00 44.87 ? 130 HIS A CE1 1 ATOM 967 N NE2 . HIS A 1 130 ? 4.387 -11.986 54.237 1.00 44.67 ? 130 HIS A NE2 1 ATOM 968 N N . ASP A 1 131 ? 7.641 -9.140 52.493 1.00 45.81 ? 131 ASP A N 1 ATOM 969 C CA . ASP A 1 131 ? 8.831 -8.880 53.275 1.00 46.09 ? 131 ASP A CA 1 ATOM 970 C C . ASP A 1 131 ? 9.471 -10.217 53.644 1.00 46.22 ? 131 ASP A C 1 ATOM 971 O O . ASP A 1 131 ? 8.800 -11.248 53.692 1.00 45.73 ? 131 ASP A O 1 ATOM 972 C CB . ASP A 1 131 ? 8.371 -8.147 54.533 1.00 46.10 ? 131 ASP A CB 1 ATOM 973 C CG . ASP A 1 131 ? 9.496 -7.826 55.482 1.00 47.57 ? 131 ASP A CG 1 ATOM 974 O OD1 . ASP A 1 131 ? 10.225 -6.845 55.226 1.00 48.44 ? 131 ASP A OD1 1 ATOM 975 O OD2 . ASP A 1 131 ? 9.631 -8.533 56.512 1.00 50.06 ? 131 ASP A OD2 1 ATOM 976 N N . CYS A 1 132 ? 10.771 -10.215 53.874 1.00 47.13 ? 132 CYS A N 1 ATOM 977 C CA . CYS A 1 132 ? 11.394 -11.366 54.521 1.00 48.93 ? 132 CYS A CA 1 ATOM 978 C C . CYS A 1 132 ? 11.366 -11.172 56.081 1.00 49.74 ? 132 CYS A C 1 ATOM 979 O O . CYS A 1 132 ? 10.641 -11.857 56.838 1.00 50.44 ? 132 CYS A O 1 ATOM 980 C CB . CYS A 1 132 ? 12.804 -11.625 53.956 1.00 48.54 ? 132 CYS A CB 1 ATOM 981 S SG . CYS A 1 132 ? 13.138 -10.833 52.283 1.00 51.93 ? 132 CYS A SG 1 ATOM 982 N N . LEU B 2 1 ? 17.260 23.218 10.513 1.00 31.68 ? 1 LEU U N 1 ATOM 983 C CA . LEU B 2 1 ? 16.014 22.404 10.624 1.00 31.45 ? 1 LEU U CA 1 ATOM 984 C C . LEU B 2 1 ? 15.772 22.088 12.103 1.00 31.74 ? 1 LEU U C 1 ATOM 985 O O . LEU B 2 1 ? 16.652 21.534 12.779 1.00 31.95 ? 1 LEU U O 1 ATOM 986 C CB . LEU B 2 1 ? 16.168 21.103 9.816 1.00 31.13 ? 1 LEU U CB 1 ATOM 987 C CG . LEU B 2 1 ? 14.999 20.371 9.154 1.00 29.51 ? 1 LEU U CG 1 ATOM 988 C CD1 . LEU B 2 1 ? 15.313 18.882 9.080 1.00 28.39 ? 1 LEU U CD1 1 ATOM 989 C CD2 . LEU B 2 1 ? 13.700 20.583 9.865 1.00 27.85 ? 1 LEU U CD2 1 ATOM 990 N N . GLN B 2 2 ? 14.598 22.460 12.607 1.00 31.64 ? 2 GLN U N 1 ATOM 991 C CA . GLN B 2 2 ? 14.194 22.042 13.935 1.00 31.78 ? 2 GLN U CA 1 ATOM 992 C C . GLN B 2 2 ? 13.844 20.570 13.898 1.00 32.20 ? 2 GLN U C 1 ATOM 993 O O . GLN B 2 2 ? 13.147 20.110 13.002 1.00 31.84 ? 2 GLN U O 1 ATOM 994 C CB . GLN B 2 2 ? 13.016 22.853 14.460 1.00 31.29 ? 2 GLN U CB 1 ATOM 995 C CG . GLN B 2 2 ? 13.423 23.980 15.357 1.00 31.69 ? 2 GLN U CG 1 ATOM 996 C CD . GLN B 2 2 ? 12.251 24.847 15.805 1.00 34.52 ? 2 GLN U CD 1 ATOM 997 O OE1 . GLN B 2 2 ? 11.276 25.047 15.070 1.00 36.71 ? 2 GLN U OE1 1 ATOM 998 N NE2 . GLN B 2 2 ? 12.356 25.398 17.006 1.00 34.76 ? 2 GLN U NE2 1 ATOM 999 N N . CYS B 2 3 ? 14.358 19.837 14.876 1.00 33.05 ? 3 CYS U N 1 ATOM 1000 C CA . CYS B 2 3 ? 14.003 18.450 15.050 1.00 34.18 ? 3 CYS U CA 1 ATOM 1001 C C . CYS B 2 3 ? 14.219 17.929 16.452 1.00 33.86 ? 3 CYS U C 1 ATOM 1002 O O . CYS B 2 3 ? 15.263 18.177 17.027 1.00 34.23 ? 3 CYS U O 1 ATOM 1003 C CB . CYS B 2 3 ? 14.733 17.597 14.029 1.00 34.55 ? 3 CYS U CB 1 ATOM 1004 S SG . CYS B 2 3 ? 13.545 17.141 12.771 1.00 38.34 ? 3 CYS U SG 1 ATOM 1005 N N . MET B 2 4 ? 13.232 17.213 16.993 1.00 33.77 ? 4 MET U N 1 ATOM 1006 C CA . MET B 2 4 ? 13.320 16.662 18.350 1.00 33.98 ? 4 MET U CA 1 ATOM 1007 C C . MET B 2 4 ? 14.556 15.809 18.485 1.00 34.48 ? 4 MET U C 1 ATOM 1008 O O . MET B 2 4 ? 14.924 15.099 17.536 1.00 35.01 ? 4 MET U O 1 ATOM 1009 C CB . MET B 2 4 ? 12.129 15.786 18.674 1.00 33.61 ? 4 MET U CB 1 ATOM 1010 C CG . MET B 2 4 ? 10.832 16.376 18.305 1.00 33.90 ? 4 MET U CG 1 ATOM 1011 S SD . MET B 2 4 ? 9.990 17.071 19.704 1.00 36.66 ? 4 MET U SD 1 ATOM 1012 C CE . MET B 2 4 ? 10.880 18.590 19.979 1.00 36.84 ? 4 MET U CE 1 ATOM 1013 N N . GLN B 2 5 ? 15.192 15.883 19.653 1.00 34.50 ? 5 GLN U N 1 ATOM 1014 C CA . GLN B 2 5 ? 16.369 15.078 19.960 1.00 34.74 ? 5 GLN U CA 1 ATOM 1015 C C . GLN B 2 5 ? 16.186 14.526 21.343 1.00 34.95 ? 5 GLN U C 1 ATOM 1016 O O . GLN B 2 5 ? 15.610 15.187 22.189 1.00 35.28 ? 5 GLN U O 1 ATOM 1017 C CB . GLN B 2 5 ? 17.644 15.919 19.875 1.00 34.58 ? 5 GLN U CB 1 ATOM 1018 C CG . GLN B 2 5 ? 18.819 15.457 20.743 1.00 35.09 ? 5 GLN U CG 1 ATOM 1019 C CD . GLN B 2 5 ? 18.904 16.244 22.041 1.00 37.48 ? 5 GLN U CD 1 ATOM 1020 O OE1 . GLN B 2 5 ? 19.621 17.256 22.154 1.00 37.22 ? 5 GLN U OE1 1 ATOM 1021 N NE2 . GLN B 2 5 ? 18.140 15.804 23.024 1.00 38.85 ? 5 GLN U NE2 1 ATOM 1022 N N . CYS B 2 6 ? 16.660 13.308 21.568 1.00 35.31 ? 6 CYS U N 1 ATOM 1023 C CA . CYS B 2 6 ? 16.575 12.670 22.872 1.00 35.68 ? 6 CYS U CA 1 ATOM 1024 C C . CYS B 2 6 ? 17.027 11.229 22.795 1.00 35.62 ? 6 CYS U C 1 ATOM 1025 O O . CYS B 2 6 ? 16.428 10.419 22.110 1.00 35.06 ? 6 CYS U O 1 ATOM 1026 C CB . CYS B 2 6 ? 15.160 12.748 23.449 1.00 35.52 ? 6 CYS U CB 1 ATOM 1027 S SG . CYS B 2 6 ? 13.915 12.206 22.279 1.00 37.71 ? 6 CYS U SG 1 ATOM 1028 N N . GLU B 2 7 ? 18.110 10.948 23.509 1.00 36.12 ? 7 GLU U N 1 ATOM 1029 C CA . GLU B 2 7 ? 18.565 9.614 23.790 1.00 36.93 ? 7 GLU U CA 1 ATOM 1030 C C . GLU B 2 7 ? 17.516 8.859 24.613 1.00 36.96 ? 7 GLU U C 1 ATOM 1031 O O . GLU B 2 7 ? 16.452 9.397 24.943 1.00 36.76 ? 7 GLU U O 1 ATOM 1032 C CB . GLU B 2 7 ? 19.869 9.709 24.575 1.00 37.29 ? 7 GLU U CB 1 ATOM 1033 C CG . GLU B 2 7 ? 20.896 8.667 24.214 1.00 40.54 ? 7 GLU U CG 1 ATOM 1034 C CD . GLU B 2 7 ? 21.510 8.920 22.849 1.00 45.55 ? 7 GLU U CD 1 ATOM 1035 O OE1 . GLU B 2 7 ? 21.399 10.072 22.352 1.00 47.54 ? 7 GLU U OE1 1 ATOM 1036 O OE2 . GLU B 2 7 ? 22.100 7.969 22.270 1.00 47.49 ? 7 GLU U OE2 1 ATOM 1037 N N . SER B 2 8 ? 17.853 7.622 24.972 1.00 37.31 ? 8 SER U N 1 ATOM 1038 C CA . SER B 2 8 ? 16.914 6.649 25.524 1.00 37.74 ? 8 SER U CA 1 ATOM 1039 C C . SER B 2 8 ? 15.886 7.145 26.549 1.00 38.40 ? 8 SER U C 1 ATOM 1040 O O . SER B 2 8 ? 14.717 7.362 26.198 1.00 38.79 ? 8 SER U O 1 ATOM 1041 C CB . SER B 2 8 ? 17.671 5.469 26.109 1.00 37.45 ? 8 SER U CB 1 ATOM 1042 O OG . SER B 2 8 ? 16.748 4.462 26.478 1.00 37.53 ? 8 SER U OG 1 ATOM 1043 N N . ASN B 2 9 ? 16.324 7.303 27.802 1.00 38.48 ? 9 ASN U N 1 ATOM 1044 C CA . ASN B 2 9 ? 15.426 7.524 28.947 1.00 38.54 ? 9 ASN U CA 1 ATOM 1045 C C . ASN B 2 9 ? 15.149 9.013 29.134 1.00 38.07 ? 9 ASN U C 1 ATOM 1046 O O . ASN B 2 9 ? 14.509 9.439 30.117 1.00 37.93 ? 9 ASN U O 1 ATOM 1047 C CB . ASN B 2 9 ? 16.056 6.955 30.243 1.00 39.24 ? 9 ASN U CB 1 ATOM 1048 C CG . ASN B 2 9 ? 16.745 5.586 30.032 1.00 40.48 ? 9 ASN U CG 1 ATOM 1049 O OD1 . ASN B 2 9 ? 17.927 5.400 30.380 1.00 40.84 ? 9 ASN U OD1 1 ATOM 1050 N ND2 . ASN B 2 9 ? 16.003 4.629 29.462 1.00 40.72 ? 9 ASN U ND2 1 ATOM 1051 N N . GLN B 2 10 ? 15.672 9.802 28.199 1.00 37.16 ? 10 GLN U N 1 ATOM 1052 C CA . GLN B 2 10 ? 15.581 11.248 28.270 1.00 36.18 ? 10 GLN U CA 1 ATOM 1053 C C . GLN B 2 10 ? 14.246 11.701 27.766 1.00 35.29 ? 10 GLN U C 1 ATOM 1054 O O . GLN B 2 10 ? 13.523 10.929 27.162 1.00 35.22 ? 10 GLN U O 1 ATOM 1055 C CB . GLN B 2 10 ? 16.677 11.879 27.426 1.00 36.26 ? 10 GLN U CB 1 ATOM 1056 C CG . GLN B 2 10 ? 17.963 12.110 28.188 1.00 37.00 ? 10 GLN U CG 1 ATOM 1057 C CD . GLN B 2 10 ? 19.195 12.009 27.311 1.00 38.57 ? 10 GLN U CD 1 ATOM 1058 O OE1 . GLN B 2 10 ? 20.286 11.658 27.783 1.00 39.65 ? 10 GLN U OE1 1 ATOM 1059 N NE2 . GLN B 2 10 ? 19.032 12.305 26.024 1.00 38.93 ? 10 GLN U NE2 1 ATOM 1060 N N . SER B 2 11 ? 13.921 12.958 28.031 1.00 34.42 ? 11 SER U N 1 ATOM 1061 C CA . SER B 2 11 ? 12.790 13.608 27.399 1.00 33.59 ? 11 SER U CA 1 ATOM 1062 C C . SER B 2 11 ? 13.356 14.276 26.172 1.00 33.17 ? 11 SER U C 1 ATOM 1063 O O . SER B 2 11 ? 14.569 14.381 26.048 1.00 33.17 ? 11 SER U O 1 ATOM 1064 C CB . SER B 2 11 ? 12.212 14.659 28.327 1.00 33.49 ? 11 SER U CB 1 ATOM 1065 O OG . SER B 2 11 ? 13.184 15.650 28.556 1.00 33.10 ? 11 SER U OG 1 ATOM 1066 N N . CYS B 2 12 ? 12.497 14.736 25.268 1.00 32.73 ? 12 CYS U N 1 ATOM 1067 C CA . CYS B 2 12 ? 12.983 15.351 24.026 1.00 32.25 ? 12 CYS U CA 1 ATOM 1068 C C . CYS B 2 12 ? 13.041 16.847 24.020 1.00 30.87 ? 12 CYS U C 1 ATOM 1069 O O . CYS B 2 12 ? 12.165 17.541 24.542 1.00 30.99 ? 12 CYS U O 1 ATOM 1070 C CB . CYS B 2 12 ? 12.240 14.860 22.789 1.00 32.29 ? 12 CYS U CB 1 ATOM 1071 S SG . CYS B 2 12 ? 12.086 13.105 22.839 1.00 36.41 ? 12 CYS U SG 1 ATOM 1072 N N . LEU B 2 13 ? 14.109 17.303 23.386 1.00 29.44 ? 13 LEU U N 1 ATOM 1073 C CA . LEU B 2 13 ? 14.423 18.688 23.197 1.00 28.18 ? 13 LEU U CA 1 ATOM 1074 C C . LEU B 2 13 ? 14.114 19.064 21.763 1.00 27.22 ? 13 LEU U C 1 ATOM 1075 O O . LEU B 2 13 ? 14.045 18.203 20.913 1.00 27.33 ? 13 LEU U O 1 ATOM 1076 C CB . LEU B 2 13 ? 15.908 18.872 23.507 1.00 28.03 ? 13 LEU U CB 1 ATOM 1077 C CG . LEU B 2 13 ? 16.325 19.241 24.946 1.00 27.74 ? 13 LEU U CG 1 ATOM 1078 C CD1 . LEU B 2 13 ? 15.283 18.937 26.042 1.00 24.90 ? 13 LEU U CD1 1 ATOM 1079 C CD2 . LEU B 2 13 ? 17.708 18.662 25.265 1.00 27.80 ? 13 LEU U CD2 1 ATOM 1080 N N . VAL B 2 14 ? 13.904 20.340 21.497 1.00 26.44 ? 14 VAL U N 1 ATOM 1081 C CA . VAL B 2 14 ? 13.798 20.802 20.132 1.00 26.19 ? 14 VAL U CA 1 ATOM 1082 C C . VAL B 2 14 ? 15.182 21.193 19.673 1.00 26.62 ? 14 VAL U C 1 ATOM 1083 O O . VAL B 2 14 ? 15.575 22.329 19.802 1.00 26.66 ? 14 VAL U O 1 ATOM 1084 C CB . VAL B 2 14 ? 12.872 22.005 20.010 1.00 25.74 ? 14 VAL U CB 1 ATOM 1085 C CG1 . VAL B 2 14 ? 12.843 22.481 18.617 1.00 25.48 ? 14 VAL U CG1 1 ATOM 1086 C CG2 . VAL B 2 14 ? 11.486 21.633 20.405 1.00 25.71 ? 14 VAL U CG2 1 ATOM 1087 N N . GLU B 2 15 ? 15.930 20.227 19.165 1.00 27.52 ? 15 GLU U N 1 ATOM 1088 C CA . GLU B 2 15 ? 17.253 20.457 18.605 1.00 28.58 ? 15 GLU U CA 1 ATOM 1089 C C . GLU B 2 15 ? 17.022 21.139 17.271 1.00 28.41 ? 15 GLU U C 1 ATOM 1090 O O . GLU B 2 15 ? 15.887 21.269 16.847 1.00 28.14 ? 15 GLU U O 1 ATOM 1091 C CB . GLU B 2 15 ? 17.976 19.110 18.443 1.00 29.15 ? 15 GLU U CB 1 ATOM 1092 C CG . GLU B 2 15 ? 19.488 19.138 18.054 1.00 33.18 ? 15 GLU U CG 1 ATOM 1093 C CD . GLU B 2 15 ? 20.327 17.963 18.698 1.00 38.19 ? 15 GLU U CD 1 ATOM 1094 O OE1 . GLU B 2 15 ? 20.804 17.034 17.965 1.00 38.60 ? 15 GLU U OE1 1 ATOM 1095 O OE2 . GLU B 2 15 ? 20.509 17.981 19.949 1.00 38.99 ? 15 GLU U OE2 1 ATOM 1096 N N . GLU B 2 16 ? 18.086 21.587 16.618 1.00 28.71 ? 16 GLU U N 1 ATOM 1097 C CA . GLU B 2 16 ? 17.951 22.402 15.432 1.00 28.83 ? 16 GLU U CA 1 ATOM 1098 C C . GLU B 2 16 ? 19.221 22.326 14.631 1.00 29.17 ? 16 GLU U C 1 ATOM 1099 O O . GLU B 2 16 ? 20.235 22.873 15.044 1.00 28.91 ? 16 GLU U O 1 ATOM 1100 C CB . GLU B 2 16 ? 17.679 23.839 15.837 1.00 28.59 ? 16 GLU U CB 1 ATOM 1101 C CG . GLU B 2 16 ? 16.768 24.565 14.876 1.00 29.33 ? 16 GLU U CG 1 ATOM 1102 C CD . GLU B 2 16 ? 17.490 25.172 13.682 1.00 29.62 ? 16 GLU U CD 1 ATOM 1103 O OE1 . GLU B 2 16 ? 16.907 26.067 13.038 1.00 30.22 ? 16 GLU U OE1 1 ATOM 1104 O OE2 . GLU B 2 16 ? 18.635 24.775 13.387 1.00 29.65 ? 16 GLU U OE2 1 ATOM 1105 N N . CYS B 2 17 ? 19.151 21.673 13.475 1.00 30.00 ? 17 CYS U N 1 ATOM 1106 C CA . CYS B 2 17 ? 20.344 21.205 12.768 1.00 31.49 ? 17 CYS U CA 1 ATOM 1107 C C . CYS B 2 17 ? 21.129 22.309 12.096 1.00 32.01 ? 17 CYS U C 1 ATOM 1108 O O . CYS B 2 17 ? 20.604 23.385 11.873 1.00 32.34 ? 17 CYS U O 1 ATOM 1109 C CB . CYS B 2 17 ? 19.969 20.165 11.729 1.00 31.74 ? 17 CYS U CB 1 ATOM 1110 S SG . CYS B 2 17 ? 18.527 19.133 12.111 1.00 34.97 ? 17 CYS U SG 1 ATOM 1111 N N . ALA B 2 18 ? 22.390 22.046 11.771 1.00 33.04 ? 18 ALA U N 1 ATOM 1112 C CA . ALA B 2 18 ? 23.203 23.038 11.059 1.00 34.23 ? 18 ALA U CA 1 ATOM 1113 C C . ALA B 2 18 ? 23.367 22.672 9.597 1.00 35.02 ? 18 ALA U C 1 ATOM 1114 O O . ALA B 2 18 ? 23.089 21.535 9.197 1.00 35.01 ? 18 ALA U O 1 ATOM 1115 C CB . ALA B 2 18 ? 24.573 23.201 11.712 1.00 34.42 ? 18 ALA U CB 1 ATOM 1116 N N . LEU B 2 19 ? 23.821 23.643 8.805 1.00 36.14 ? 19 LEU U N 1 ATOM 1117 C CA . LEU B 2 19 ? 24.144 23.392 7.410 1.00 37.24 ? 19 LEU U CA 1 ATOM 1118 C C . LEU B 2 19 ? 24.980 22.122 7.372 1.00 37.86 ? 19 LEU U C 1 ATOM 1119 O O . LEU B 2 19 ? 26.132 22.092 7.829 1.00 37.91 ? 19 LEU U O 1 ATOM 1120 C CB . LEU B 2 19 ? 24.901 24.567 6.759 1.00 37.36 ? 19 LEU U CB 1 ATOM 1121 C CG . LEU B 2 19 ? 24.845 24.758 5.222 1.00 37.80 ? 19 LEU U CG 1 ATOM 1122 C CD1 . LEU B 2 19 ? 25.788 25.880 4.770 1.00 38.01 ? 19 LEU U CD1 1 ATOM 1123 C CD2 . LEU B 2 19 ? 25.090 23.481 4.376 1.00 37.39 ? 19 LEU U CD2 1 ATOM 1124 N N . GLY B 2 20 ? 24.353 21.070 6.850 1.00 38.59 ? 20 GLY U N 1 ATOM 1125 C CA . GLY B 2 20 ? 24.949 19.750 6.723 1.00 39.02 ? 20 GLY U CA 1 ATOM 1126 C C . GLY B 2 20 ? 23.911 18.708 7.069 1.00 39.25 ? 20 GLY U C 1 ATOM 1127 O O . GLY B 2 20 ? 23.814 17.674 6.401 1.00 39.44 ? 20 GLY U O 1 ATOM 1128 N N . GLN B 2 21 ? 23.134 18.992 8.113 1.00 39.45 ? 21 GLN U N 1 ATOM 1129 C CA . GLN B 2 21 ? 22.165 18.040 8.643 1.00 39.58 ? 21 GLN U CA 1 ATOM 1130 C C . GLN B 2 21 ? 20.777 18.478 8.210 1.00 38.98 ? 21 GLN U C 1 ATOM 1131 O O . GLN B 2 21 ? 20.366 19.615 8.474 1.00 38.51 ? 21 GLN U O 1 ATOM 1132 C CB . GLN B 2 21 ? 22.247 17.968 10.167 1.00 40.02 ? 21 GLN U CB 1 ATOM 1133 C CG . GLN B 2 21 ? 23.528 18.539 10.802 1.00 42.01 ? 21 GLN U CG 1 ATOM 1134 C CD . GLN B 2 21 ? 23.446 18.564 12.331 1.00 44.98 ? 21 GLN U CD 1 ATOM 1135 O OE1 . GLN B 2 21 ? 23.885 19.523 12.987 1.00 46.20 ? 21 GLN U OE1 1 ATOM 1136 N NE2 . GLN B 2 21 ? 22.862 17.509 12.903 1.00 45.01 ? 21 GLN U NE2 1 ATOM 1137 N N . ASP B 2 22 ? 20.065 17.581 7.529 1.00 38.46 ? 22 ASP U N 1 ATOM 1138 C CA . ASP B 2 22 ? 18.803 17.953 6.888 1.00 38.10 ? 22 ASP U CA 1 ATOM 1139 C C . ASP B 2 22 ? 17.752 16.866 6.969 1.00 37.62 ? 22 ASP U C 1 ATOM 1140 O O . ASP B 2 22 ? 16.822 16.808 6.158 1.00 37.58 ? 22 ASP U O 1 ATOM 1141 C CB . ASP B 2 22 ? 19.015 18.436 5.434 1.00 38.17 ? 22 ASP U CB 1 ATOM 1142 C CG . ASP B 2 22 ? 19.540 17.349 4.497 1.00 38.71 ? 22 ASP U CG 1 ATOM 1143 O OD1 . ASP B 2 22 ? 20.409 17.687 3.662 1.00 40.12 ? 22 ASP U OD1 1 ATOM 1144 O OD2 . ASP B 2 22 ? 19.087 16.181 4.558 1.00 39.04 ? 22 ASP U OD2 1 ATOM 1145 N N . LEU B 2 23 ? 17.894 16.014 7.968 1.00 36.96 ? 23 LEU U N 1 ATOM 1146 C CA . LEU B 2 23 ? 17.000 14.894 8.107 1.00 36.24 ? 23 LEU U CA 1 ATOM 1147 C C . LEU B 2 23 ? 16.788 14.628 9.573 1.00 36.17 ? 23 LEU U C 1 ATOM 1148 O O . LEU B 2 23 ? 17.610 15.037 10.391 1.00 36.37 ? 23 LEU U O 1 ATOM 1149 C CB . LEU B 2 23 ? 17.626 13.677 7.439 1.00 35.95 ? 23 LEU U CB 1 ATOM 1150 C CG . LEU B 2 23 ? 17.483 13.576 5.937 1.00 34.55 ? 23 LEU U CG 1 ATOM 1151 C CD1 . LEU B 2 23 ? 17.997 12.231 5.501 1.00 34.00 ? 23 LEU U CD1 1 ATOM 1152 C CD2 . LEU B 2 23 ? 16.022 13.737 5.584 1.00 33.54 ? 23 LEU U CD2 1 ATOM 1153 N N . CYS B 2 24 ? 15.708 13.927 9.916 1.00 35.71 ? 24 CYS U N 1 ATOM 1154 C CA . CYS B 2 24 ? 15.414 13.666 11.328 1.00 35.45 ? 24 CYS U CA 1 ATOM 1155 C C . CYS B 2 24 ? 15.312 12.238 11.716 1.00 34.44 ? 24 CYS U C 1 ATOM 1156 O O . CYS B 2 24 ? 14.306 11.577 11.463 1.00 34.98 ? 24 CYS U O 1 ATOM 1157 C CB . CYS B 2 24 ? 14.190 14.425 11.765 1.00 35.57 ? 24 CYS U CB 1 ATOM 1158 S SG . CYS B 2 24 ? 14.659 16.057 11.504 1.00 39.39 ? 24 CYS U SG 1 ATOM 1159 N N . ARG B 2 25 ? 16.377 11.785 12.361 1.00 33.01 ? 25 ARG U N 1 ATOM 1160 C CA . ARG B 2 25 ? 16.560 10.418 12.770 1.00 31.23 ? 25 ARG U CA 1 ATOM 1161 C C . ARG B 2 25 ? 15.525 10.087 13.819 1.00 30.31 ? 25 ARG U C 1 ATOM 1162 O O . ARG B 2 25 ? 15.124 10.962 14.592 1.00 29.66 ? 25 ARG U O 1 ATOM 1163 C CB . ARG B 2 25 ? 17.943 10.309 13.359 1.00 31.34 ? 25 ARG U CB 1 ATOM 1164 C CG . ARG B 2 25 ? 18.696 9.073 13.022 1.00 31.67 ? 25 ARG U CG 1 ATOM 1165 C CD . ARG B 2 25 ? 20.040 9.009 13.797 1.00 32.90 ? 25 ARG U CD 1 ATOM 1166 N NE . ARG B 2 25 ? 20.008 9.667 15.108 1.00 32.00 ? 25 ARG U NE 1 ATOM 1167 C CZ . ARG B 2 25 ? 19.256 9.289 16.137 1.00 30.60 ? 25 ARG U CZ 1 ATOM 1168 N NH1 . ARG B 2 25 ? 18.438 8.251 16.048 1.00 27.70 ? 25 ARG U NH1 1 ATOM 1169 N NH2 . ARG B 2 25 ? 19.317 9.980 17.260 1.00 33.11 ? 25 ARG U NH2 1 ATOM 1170 N N . THR B 2 26 ? 15.064 8.835 13.780 1.00 29.51 ? 26 THR U N 1 ATOM 1171 C CA . THR B 2 26 ? 14.157 8.240 14.763 1.00 28.87 ? 26 THR U CA 1 ATOM 1172 C C . THR B 2 26 ? 14.478 6.761 14.772 1.00 28.95 ? 26 THR U C 1 ATOM 1173 O O . THR B 2 26 ? 13.734 5.961 14.227 1.00 29.41 ? 26 THR U O 1 ATOM 1174 C CB . THR B 2 26 ? 12.683 8.397 14.382 1.00 28.32 ? 26 THR U CB 1 ATOM 1175 O OG1 . THR B 2 26 ? 12.485 9.693 13.834 1.00 29.45 ? 26 THR U OG1 1 ATOM 1176 C CG2 . THR B 2 26 ? 11.764 8.217 15.574 1.00 27.05 ? 26 THR U CG2 1 ATOM 1177 N N . THR B 2 27 ? 15.601 6.405 15.379 1.00 28.92 ? 27 THR U N 1 ATOM 1178 C CA . THR B 2 27 ? 16.000 5.017 15.518 1.00 28.92 ? 27 THR U CA 1 ATOM 1179 C C . THR B 2 27 ? 15.234 4.304 16.644 1.00 29.18 ? 27 THR U C 1 ATOM 1180 O O . THR B 2 27 ? 15.206 4.784 17.770 1.00 29.88 ? 27 THR U O 1 ATOM 1181 C CB . THR B 2 27 ? 17.478 4.934 15.813 1.00 28.51 ? 27 THR U CB 1 ATOM 1182 O OG1 . THR B 2 27 ? 18.149 5.968 15.094 1.00 28.44 ? 27 THR U OG1 1 ATOM 1183 C CG2 . THR B 2 27 ? 18.019 3.600 15.367 1.00 29.34 ? 27 THR U CG2 1 ATOM 1184 N N . VAL B 2 28 ? 14.614 3.164 16.337 1.00 28.96 ? 28 VAL U N 1 ATOM 1185 C CA . VAL B 2 28 ? 14.076 2.289 17.371 1.00 28.37 ? 28 VAL U CA 1 ATOM 1186 C C . VAL B 2 28 ? 14.790 0.935 17.373 1.00 28.66 ? 28 VAL U C 1 ATOM 1187 O O . VAL B 2 28 ? 15.129 0.422 16.317 1.00 28.30 ? 28 VAL U O 1 ATOM 1188 C CB . VAL B 2 28 ? 12.566 2.146 17.260 1.00 27.95 ? 28 VAL U CB 1 ATOM 1189 C CG1 . VAL B 2 28 ? 12.121 2.386 15.870 1.00 27.53 ? 28 VAL U CG1 1 ATOM 1190 C CG2 . VAL B 2 28 ? 12.116 0.791 17.760 1.00 27.85 ? 28 VAL U CG2 1 ATOM 1191 N N . LEU B 2 29 ? 15.074 0.418 18.572 1.00 29.31 ? 29 LEU U N 1 ATOM 1192 C CA . LEU B 2 29 ? 15.577 -0.946 18.792 1.00 30.20 ? 29 LEU U CA 1 ATOM 1193 C C . LEU B 2 29 ? 14.603 -1.728 19.676 1.00 31.31 ? 29 LEU U C 1 ATOM 1194 O O . LEU B 2 29 ? 14.244 -1.236 20.735 1.00 32.06 ? 29 LEU U O 1 ATOM 1195 C CB . LEU B 2 29 ? 16.952 -0.920 19.452 1.00 29.64 ? 29 LEU U CB 1 ATOM 1196 C CG . LEU B 2 29 ? 17.516 -2.242 20.003 1.00 29.41 ? 29 LEU U CG 1 ATOM 1197 C CD1 . LEU B 2 29 ? 18.971 -2.489 19.568 1.00 27.84 ? 29 LEU U CD1 1 ATOM 1198 C CD2 . LEU B 2 29 ? 17.392 -2.341 21.526 1.00 28.34 ? 29 LEU U CD2 1 ATOM 1199 N N . ARG B 2 30 ? 14.182 -2.927 19.250 1.00 32.24 ? 30 ARG U N 1 ATOM 1200 C CA . ARG B 2 30 ? 13.219 -3.759 19.994 1.00 33.17 ? 30 ARG U CA 1 ATOM 1201 C C . ARG B 2 30 ? 13.843 -5.107 20.288 1.00 33.37 ? 30 ARG U C 1 ATOM 1202 O O . ARG B 2 30 ? 14.805 -5.485 19.639 1.00 33.96 ? 30 ARG U O 1 ATOM 1203 C CB . ARG B 2 30 ? 11.962 -4.013 19.175 1.00 33.42 ? 30 ARG U CB 1 ATOM 1204 C CG . ARG B 2 30 ? 11.310 -2.798 18.587 1.00 36.55 ? 30 ARG U CG 1 ATOM 1205 C CD . ARG B 2 30 ? 9.940 -2.576 19.197 1.00 42.28 ? 30 ARG U CD 1 ATOM 1206 N NE . ARG B 2 30 ? 9.081 -1.752 18.338 1.00 45.97 ? 30 ARG U NE 1 ATOM 1207 C CZ . ARG B 2 30 ? 7.749 -1.716 18.414 1.00 48.55 ? 30 ARG U CZ 1 ATOM 1208 N NH1 . ARG B 2 30 ? 7.098 -2.466 19.313 1.00 49.29 ? 30 ARG U NH1 1 ATOM 1209 N NH2 . ARG B 2 30 ? 7.060 -0.936 17.582 1.00 49.43 ? 30 ARG U NH2 1 ATOM 1210 N N . GLU B 2 31 ? 13.298 -5.823 21.266 1.00 33.59 ? 31 GLU U N 1 ATOM 1211 C CA . GLU B 2 31 ? 13.652 -7.214 21.542 1.00 33.80 ? 31 GLU U CA 1 ATOM 1212 C C . GLU B 2 31 ? 12.397 -7.929 21.978 1.00 33.81 ? 31 GLU U C 1 ATOM 1213 O O . GLU B 2 31 ? 11.577 -7.383 22.725 1.00 33.89 ? 31 GLU U O 1 ATOM 1214 C CB . GLU B 2 31 ? 14.637 -7.335 22.699 1.00 34.21 ? 31 GLU U CB 1 ATOM 1215 C CG . GLU B 2 31 ? 16.042 -6.817 22.469 1.00 36.25 ? 31 GLU U CG 1 ATOM 1216 C CD . GLU B 2 31 ? 16.633 -6.177 23.737 1.00 39.55 ? 31 GLU U CD 1 ATOM 1217 O OE1 . GLU B 2 31 ? 17.740 -6.612 24.181 1.00 39.27 ? 31 GLU U OE1 1 ATOM 1218 O OE2 . GLU B 2 31 ? 15.973 -5.238 24.279 1.00 40.16 ? 31 GLU U OE2 1 ATOM 1219 N N . TRP B 2 32 ? 12.242 -9.158 21.518 1.00 33.85 ? 32 TRP U N 1 ATOM 1220 C CA . TRP B 2 32 ? 11.223 -10.022 22.063 1.00 33.75 ? 32 TRP U CA 1 ATOM 1221 C C . TRP B 2 32 ? 11.941 -11.263 22.536 1.00 33.93 ? 32 TRP U C 1 ATOM 1222 O O . TRP B 2 32 ? 12.948 -11.684 21.973 1.00 33.44 ? 32 TRP U O 1 ATOM 1223 C CB . TRP B 2 32 ? 10.151 -10.346 21.019 1.00 33.83 ? 32 TRP U CB 1 ATOM 1224 C CG . TRP B 2 32 ? 9.209 -11.488 21.375 1.00 33.66 ? 32 TRP U CG 1 ATOM 1225 C CD1 . TRP B 2 32 ? 9.448 -12.827 21.226 1.00 33.08 ? 32 TRP U CD1 1 ATOM 1226 C CD2 . TRP B 2 32 ? 7.885 -11.377 21.905 1.00 33.60 ? 32 TRP U CD2 1 ATOM 1227 N NE1 . TRP B 2 32 ? 8.367 -13.551 21.646 1.00 32.99 ? 32 TRP U NE1 1 ATOM 1228 C CE2 . TRP B 2 32 ? 7.391 -12.688 22.069 1.00 33.83 ? 32 TRP U CE2 1 ATOM 1229 C CE3 . TRP B 2 32 ? 7.068 -10.295 22.266 1.00 34.90 ? 32 TRP U CE3 1 ATOM 1230 C CZ2 . TRP B 2 32 ? 6.106 -12.951 22.576 1.00 35.13 ? 32 TRP U CZ2 1 ATOM 1231 C CZ3 . TRP B 2 32 ? 5.786 -10.553 22.781 1.00 35.52 ? 32 TRP U CZ3 1 ATOM 1232 C CH2 . TRP B 2 32 ? 5.318 -11.875 22.920 1.00 35.68 ? 32 TRP U CH2 1 ATOM 1233 N N . GLN B 2 33 ? 11.422 -11.811 23.612 1.00 34.34 ? 33 GLN U N 1 ATOM 1234 C CA . GLN B 2 33 ? 11.859 -13.065 24.117 1.00 35.03 ? 33 GLN U CA 1 ATOM 1235 C C . GLN B 2 33 ? 10.869 -13.351 25.206 1.00 35.98 ? 33 GLN U C 1 ATOM 1236 O O . GLN B 2 33 ? 10.419 -12.429 25.903 1.00 36.01 ? 33 GLN U O 1 ATOM 1237 C CB . GLN B 2 33 ? 13.238 -12.930 24.706 1.00 34.82 ? 33 GLN U CB 1 ATOM 1238 C CG . GLN B 2 33 ? 13.854 -14.239 25.074 1.00 35.17 ? 33 GLN U CG 1 ATOM 1239 C CD . GLN B 2 33 ? 14.994 -14.076 26.051 1.00 35.54 ? 33 GLN U CD 1 ATOM 1240 O OE1 . GLN B 2 33 ? 14.999 -13.151 26.873 1.00 34.94 ? 33 GLN U OE1 1 ATOM 1241 N NE2 . GLN B 2 33 ? 15.971 -14.983 25.976 1.00 35.39 ? 33 GLN U NE2 1 ATOM 1242 N N . ASP B 2 34 ? 10.509 -14.627 25.324 1.00 37.16 ? 34 ASP U N 1 ATOM 1243 C CA . ASP B 2 34 ? 9.620 -15.131 26.387 1.00 38.24 ? 34 ASP U CA 1 ATOM 1244 C C . ASP B 2 34 ? 8.543 -14.094 26.795 1.00 38.47 ? 34 ASP U C 1 ATOM 1245 O O . ASP B 2 34 ? 8.474 -13.647 27.949 1.00 38.96 ? 34 ASP U O 1 ATOM 1246 C CB . ASP B 2 34 ? 10.451 -15.660 27.582 1.00 38.42 ? 34 ASP U CB 1 ATOM 1247 C CG . ASP B 2 34 ? 11.399 -16.840 27.194 1.00 39.56 ? 34 ASP U CG 1 ATOM 1248 O OD1 . ASP B 2 34 ? 12.431 -16.616 26.511 1.00 39.49 ? 34 ASP U OD1 1 ATOM 1249 O OD2 . ASP B 2 34 ? 11.124 -17.997 27.604 1.00 41.13 ? 34 ASP U OD2 1 ATOM 1250 N N . ASP B 2 35 ? 7.723 -13.724 25.812 1.00 38.44 ? 35 ASP U N 1 ATOM 1251 C CA . ASP B 2 35 ? 6.803 -12.588 25.886 1.00 38.68 ? 35 ASP U CA 1 ATOM 1252 C C . ASP B 2 35 ? 7.227 -11.374 26.728 1.00 38.11 ? 35 ASP U C 1 ATOM 1253 O O . ASP B 2 35 ? 6.461 -10.912 27.586 1.00 38.29 ? 35 ASP U O 1 ATOM 1254 C CB . ASP B 2 35 ? 5.388 -13.035 26.265 1.00 39.11 ? 35 ASP U CB 1 ATOM 1255 C CG . ASP B 2 35 ? 4.358 -11.891 26.142 1.00 41.59 ? 35 ASP U CG 1 ATOM 1256 O OD1 . ASP B 2 35 ? 4.510 -11.010 25.249 1.00 43.95 ? 35 ASP U OD1 1 ATOM 1257 O OD2 . ASP B 2 35 ? 3.403 -11.858 26.953 1.00 43.65 ? 35 ASP U OD2 1 ATOM 1258 N N . ARG B 2 36 ? 8.434 -10.861 26.492 1.00 37.25 ? 36 ARG U N 1 ATOM 1259 C CA . ARG B 2 36 ? 8.815 -9.561 27.052 1.00 36.48 ? 36 ARG U CA 1 ATOM 1260 C C . ARG B 2 36 ? 9.371 -8.704 25.932 1.00 36.53 ? 36 ARG U C 1 ATOM 1261 O O . ARG B 2 36 ? 10.535 -8.906 25.539 1.00 37.01 ? 36 ARG U O 1 ATOM 1262 C CB . ARG B 2 36 ? 9.884 -9.657 28.151 1.00 35.93 ? 36 ARG U CB 1 ATOM 1263 C CG . ARG B 2 36 ? 9.849 -10.862 29.054 1.00 34.77 ? 36 ARG U CG 1 ATOM 1264 C CD . ARG B 2 36 ? 10.878 -10.731 30.179 1.00 31.94 ? 36 ARG U CD 1 ATOM 1265 N NE . ARG B 2 36 ? 12.202 -10.309 29.717 1.00 29.49 ? 36 ARG U NE 1 ATOM 1266 C CZ . ARG B 2 36 ? 13.158 -11.127 29.271 1.00 28.64 ? 36 ARG U CZ 1 ATOM 1267 N NH1 . ARG B 2 36 ? 12.969 -12.450 29.203 1.00 27.40 ? 36 ARG U NH1 1 ATOM 1268 N NH2 . ARG B 2 36 ? 14.316 -10.611 28.880 1.00 27.73 ? 36 ARG U NH2 1 ATOM 1269 N N . GLU B 2 37 ? 8.560 -7.771 25.406 1.00 35.94 ? 37 GLU U N 1 ATOM 1270 C CA . GLU B 2 37 ? 9.065 -6.778 24.435 1.00 35.18 ? 37 GLU U CA 1 ATOM 1271 C C . GLU B 2 37 ? 9.596 -5.577 25.198 1.00 34.05 ? 37 GLU U C 1 ATOM 1272 O O . GLU B 2 37 ? 8.940 -5.058 26.098 1.00 33.94 ? 37 GLU U O 1 ATOM 1273 C CB . GLU B 2 37 ? 8.055 -6.424 23.306 1.00 35.35 ? 37 GLU U CB 1 ATOM 1274 C CG . GLU B 2 37 ? 7.232 -5.104 23.417 1.00 38.15 ? 37 GLU U CG 1 ATOM 1275 C CD . GLU B 2 37 ? 7.094 -4.321 22.061 1.00 42.02 ? 37 GLU U CD 1 ATOM 1276 O OE1 . GLU B 2 37 ? 5.939 -3.985 21.665 1.00 42.37 ? 37 GLU U OE1 1 ATOM 1277 O OE2 . GLU B 2 37 ? 8.139 -4.030 21.401 1.00 42.18 ? 37 GLU U OE2 1 ATOM 1278 N N . LEU B 2 38 ? 10.821 -5.198 24.880 1.00 32.85 ? 38 LEU U N 1 ATOM 1279 C CA . LEU B 2 38 ? 11.440 -4.047 25.472 1.00 32.27 ? 38 LEU U CA 1 ATOM 1280 C C . LEU B 2 38 ? 11.975 -3.271 24.301 1.00 32.09 ? 38 LEU U C 1 ATOM 1281 O O . LEU B 2 38 ? 12.755 -3.823 23.517 1.00 32.00 ? 38 LEU U O 1 ATOM 1282 C CB . LEU B 2 38 ? 12.603 -4.471 26.379 1.00 32.49 ? 38 LEU U CB 1 ATOM 1283 C CG . LEU B 2 38 ? 13.793 -3.488 26.514 1.00 32.01 ? 38 LEU U CG 1 ATOM 1284 C CD1 . LEU B 2 38 ? 13.596 -2.473 27.660 1.00 30.94 ? 38 LEU U CD1 1 ATOM 1285 C CD2 . LEU B 2 38 ? 15.126 -4.184 26.633 1.00 29.87 ? 38 LEU U CD2 1 ATOM 1286 N N . GLU B 2 39 ? 11.592 -1.996 24.194 1.00 31.62 ? 39 GLU U N 1 ATOM 1287 C CA . GLU B 2 39 ? 11.969 -1.183 23.030 1.00 31.40 ? 39 GLU U CA 1 ATOM 1288 C C . GLU B 2 39 ? 12.592 0.187 23.344 1.00 30.22 ? 39 GLU U C 1 ATOM 1289 O O . GLU B 2 39 ? 12.037 0.962 24.108 1.00 30.32 ? 39 GLU U O 1 ATOM 1290 C CB . GLU B 2 39 ? 10.774 -1.094 22.082 1.00 31.90 ? 39 GLU U CB 1 ATOM 1291 C CG . GLU B 2 39 ? 10.450 0.263 21.557 1.00 35.50 ? 39 GLU U CG 1 ATOM 1292 C CD . GLU B 2 39 ? 9.020 0.647 21.924 1.00 41.71 ? 39 GLU U CD 1 ATOM 1293 O OE1 . GLU B 2 39 ? 8.791 1.133 23.075 1.00 43.21 ? 39 GLU U OE1 1 ATOM 1294 O OE2 . GLU B 2 39 ? 8.122 0.450 21.063 1.00 44.43 ? 39 GLU U OE2 1 ATOM 1295 N N . VAL B 2 40 ? 13.751 0.462 22.749 1.00 29.10 ? 40 VAL U N 1 ATOM 1296 C CA . VAL B 2 40 ? 14.511 1.699 22.981 1.00 28.22 ? 40 VAL U CA 1 ATOM 1297 C C . VAL B 2 40 ? 14.702 2.558 21.722 1.00 27.96 ? 40 VAL U C 1 ATOM 1298 O O . VAL B 2 40 ? 15.365 2.159 20.758 1.00 28.11 ? 40 VAL U O 1 ATOM 1299 C CB . VAL B 2 40 ? 15.877 1.468 23.763 1.00 28.24 ? 40 VAL U CB 1 ATOM 1300 C CG1 . VAL B 2 40 ? 16.329 0.032 23.706 1.00 28.58 ? 40 VAL U CG1 1 ATOM 1301 C CG2 . VAL B 2 40 ? 16.994 2.391 23.282 1.00 27.18 ? 40 VAL U CG2 1 ATOM 1302 N N . VAL B 2 41 ? 14.112 3.752 21.775 1.00 27.49 ? 41 VAL U N 1 ATOM 1303 C CA . VAL B 2 41 ? 14.113 4.750 20.711 1.00 26.83 ? 41 VAL U CA 1 ATOM 1304 C C . VAL B 2 41 ? 15.125 5.868 20.985 1.00 26.21 ? 41 VAL U C 1 ATOM 1305 O O . VAL B 2 41 ? 15.247 6.315 22.109 1.00 26.57 ? 41 VAL U O 1 ATOM 1306 C CB . VAL B 2 41 ? 12.736 5.425 20.646 1.00 26.85 ? 41 VAL U CB 1 ATOM 1307 C CG1 . VAL B 2 41 ? 12.651 6.364 19.431 1.00 28.17 ? 41 VAL U CG1 1 ATOM 1308 C CG2 . VAL B 2 41 ? 11.615 4.383 20.625 1.00 26.63 ? 41 VAL U CG2 1 ATOM 1309 N N . THR B 2 42 ? 15.858 6.303 19.972 1.00 25.53 ? 42 THR U N 1 ATOM 1310 C CA . THR B 2 42 ? 16.601 7.534 20.070 1.00 25.59 ? 42 THR U CA 1 ATOM 1311 C C . THR B 2 42 ? 16.312 8.380 18.850 1.00 26.21 ? 42 THR U C 1 ATOM 1312 O O . THR B 2 42 ? 16.211 7.871 17.749 1.00 26.51 ? 42 THR U O 1 ATOM 1313 C CB . THR B 2 42 ? 18.134 7.355 20.233 1.00 25.45 ? 42 THR U CB 1 ATOM 1314 O OG1 . THR B 2 42 ? 18.685 6.671 19.107 1.00 25.18 ? 42 THR U OG1 1 ATOM 1315 C CG2 . THR B 2 42 ? 18.481 6.607 21.496 1.00 25.60 ? 42 THR U CG2 1 ATOM 1316 N N . ARG B 2 43 ? 16.184 9.684 19.066 1.00 27.07 ? 43 ARG U N 1 ATOM 1317 C CA . ARG B 2 43 ? 15.899 10.651 18.017 1.00 27.54 ? 43 ARG U CA 1 ATOM 1318 C C . ARG B 2 43 ? 16.928 11.788 18.036 1.00 28.22 ? 43 ARG U C 1 ATOM 1319 O O . ARG B 2 43 ? 17.622 11.981 19.023 1.00 28.18 ? 43 ARG U O 1 ATOM 1320 C CB . ARG B 2 43 ? 14.501 11.227 18.199 1.00 27.12 ? 43 ARG U CB 1 ATOM 1321 C CG . ARG B 2 43 ? 13.498 10.242 18.627 1.00 26.34 ? 43 ARG U CG 1 ATOM 1322 C CD . ARG B 2 43 ? 12.399 10.981 19.269 1.00 27.01 ? 43 ARG U CD 1 ATOM 1323 N NE . ARG B 2 43 ? 11.131 10.602 18.678 1.00 29.41 ? 43 ARG U NE 1 ATOM 1324 C CZ . ARG B 2 43 ? 10.251 9.789 19.246 1.00 29.72 ? 43 ARG U CZ 1 ATOM 1325 N NH1 . ARG B 2 43 ? 10.483 9.279 20.443 1.00 29.53 ? 43 ARG U NH1 1 ATOM 1326 N NH2 . ARG B 2 43 ? 9.122 9.508 18.617 1.00 31.18 ? 43 ARG U NH2 1 ATOM 1327 N N . GLY B 2 44 ? 17.022 12.524 16.938 1.00 29.08 ? 44 GLY U N 1 ATOM 1328 C CA . GLY B 2 44 ? 17.967 13.609 16.833 1.00 30.78 ? 44 GLY U CA 1 ATOM 1329 C C . GLY B 2 44 ? 18.048 13.982 15.384 1.00 32.08 ? 44 GLY U C 1 ATOM 1330 O O . GLY B 2 44 ? 17.326 13.384 14.581 1.00 32.32 ? 44 GLY U O 1 ATOM 1331 N N . CYS B 2 45 ? 18.885 14.980 15.056 1.00 33.22 ? 45 CYS U N 1 ATOM 1332 C CA . CYS B 2 45 ? 19.142 15.356 13.656 1.00 34.69 ? 45 CYS U CA 1 ATOM 1333 C C . CYS B 2 45 ? 19.922 14.256 13.006 1.00 34.72 ? 45 CYS U C 1 ATOM 1334 O O . CYS B 2 45 ? 20.798 13.666 13.644 1.00 34.80 ? 45 CYS U O 1 ATOM 1335 C CB . CYS B 2 45 ? 19.921 16.669 13.508 1.00 34.60 ? 45 CYS U CB 1 ATOM 1336 S SG . CYS B 2 45 ? 18.958 18.185 13.899 1.00 39.32 ? 45 CYS U SG 1 ATOM 1337 N N . ALA B 2 46 ? 19.578 13.974 11.751 1.00 35.22 ? 46 ALA U N 1 ATOM 1338 C CA . ALA B 2 46 ? 20.270 12.971 10.969 1.00 36.10 ? 46 ALA U CA 1 ATOM 1339 C C . ALA B 2 46 ? 21.389 13.602 10.158 1.00 36.92 ? 46 ALA U C 1 ATOM 1340 O O . ALA B 2 46 ? 22.337 14.184 10.709 1.00 36.71 ? 46 ALA U O 1 ATOM 1341 C CB . ALA B 2 46 ? 19.312 12.262 10.072 1.00 35.89 ? 46 ALA U CB 1 ATOM 1342 N N . HIS B 2 47 ? 21.274 13.488 8.843 1.00 38.11 ? 47 HIS U N 1 ATOM 1343 C CA . HIS B 2 47 ? 22.279 14.054 7.973 1.00 39.25 ? 47 HIS U CA 1 ATOM 1344 C C . HIS B 2 47 ? 21.955 14.000 6.513 1.00 38.98 ? 47 HIS U C 1 ATOM 1345 O O . HIS B 2 47 ? 20.968 13.385 6.099 1.00 39.03 ? 47 HIS U O 1 ATOM 1346 C CB . HIS B 2 47 ? 23.629 13.390 8.198 1.00 39.96 ? 47 HIS U CB 1 ATOM 1347 C CG . HIS B 2 47 ? 24.598 14.265 8.918 1.00 42.64 ? 47 HIS U CG 1 ATOM 1348 N ND1 . HIS B 2 47 ? 24.901 15.542 8.487 1.00 44.79 ? 47 HIS U ND1 1 ATOM 1349 C CD2 . HIS B 2 47 ? 25.339 14.053 10.031 1.00 44.75 ? 47 HIS U CD2 1 ATOM 1350 C CE1 . HIS B 2 47 ? 25.792 16.077 9.303 1.00 45.95 ? 47 HIS U CE1 1 ATOM 1351 N NE2 . HIS B 2 47 ? 26.074 15.196 10.248 1.00 46.51 ? 47 HIS U NE2 1 ATOM 1352 N N . SER B 2 48 ? 22.835 14.651 5.754 1.00 38.73 ? 48 SER U N 1 ATOM 1353 C CA . SER B 2 48 ? 22.737 14.800 4.304 1.00 38.45 ? 48 SER U CA 1 ATOM 1354 C C . SER B 2 48 ? 22.127 13.564 3.641 1.00 38.09 ? 48 SER U C 1 ATOM 1355 O O . SER B 2 48 ? 21.085 13.643 2.995 1.00 37.09 ? 48 SER U O 1 ATOM 1356 C CB . SER B 2 48 ? 24.135 15.105 3.712 1.00 38.75 ? 48 SER U CB 1 ATOM 1357 O OG . SER B 2 48 ? 24.854 16.093 4.453 1.00 37.88 ? 48 SER U OG 1 ATOM 1358 N N . GLU B 2 49 ? 22.779 12.422 3.848 1.00 38.36 ? 49 GLU U N 1 ATOM 1359 C CA . GLU B 2 49 ? 22.409 11.196 3.163 1.00 38.83 ? 49 GLU U CA 1 ATOM 1360 C C . GLU B 2 49 ? 22.394 9.944 4.069 1.00 38.42 ? 49 GLU U C 1 ATOM 1361 O O . GLU B 2 49 ? 23.406 9.249 4.205 1.00 38.41 ? 49 GLU U O 1 ATOM 1362 C CB . GLU B 2 49 ? 23.331 10.972 1.948 1.00 39.37 ? 49 GLU U CB 1 ATOM 1363 C CG . GLU B 2 49 ? 23.975 12.249 1.336 1.00 40.92 ? 49 GLU U CG 1 ATOM 1364 C CD . GLU B 2 49 ? 23.081 13.006 0.336 1.00 42.59 ? 49 GLU U CD 1 ATOM 1365 O OE1 . GLU B 2 49 ? 23.283 14.239 0.182 1.00 42.96 ? 49 GLU U OE1 1 ATOM 1366 O OE2 . GLU B 2 49 ? 22.199 12.379 -0.302 1.00 42.28 ? 49 GLU U OE2 1 ATOM 1367 N N . LYS B 2 50 ? 21.243 9.687 4.694 1.00 37.89 ? 50 LYS U N 1 ATOM 1368 C CA . LYS B 2 50 ? 20.941 8.406 5.351 1.00 37.44 ? 50 LYS U CA 1 ATOM 1369 C C . LYS B 2 50 ? 19.577 7.981 4.845 1.00 37.48 ? 50 LYS U C 1 ATOM 1370 O O . LYS B 2 50 ? 18.815 8.823 4.349 1.00 37.81 ? 50 LYS U O 1 ATOM 1371 C CB . LYS B 2 50 ? 20.919 8.496 6.884 1.00 37.24 ? 50 LYS U CB 1 ATOM 1372 C CG . LYS B 2 50 ? 22.201 9.069 7.527 1.00 36.90 ? 50 LYS U CG 1 ATOM 1373 C CD . LYS B 2 50 ? 22.702 8.286 8.744 1.00 33.77 ? 50 LYS U CD 1 ATOM 1374 C CE . LYS B 2 50 ? 21.644 8.135 9.813 1.00 33.70 ? 50 LYS U CE 1 ATOM 1375 N NZ . LYS B 2 50 ? 21.862 6.874 10.589 1.00 33.34 ? 50 LYS U NZ 1 ATOM 1376 N N . THR B 2 51 ? 19.268 6.688 5.002 1.00 37.10 ? 51 THR U N 1 ATOM 1377 C CA . THR B 2 51 ? 18.214 5.978 4.235 1.00 36.21 ? 51 THR U CA 1 ATOM 1378 C C . THR B 2 51 ? 17.278 5.178 5.137 1.00 35.87 ? 51 THR U C 1 ATOM 1379 O O . THR B 2 51 ? 17.748 4.414 5.977 1.00 36.03 ? 51 THR U O 1 ATOM 1380 C CB . THR B 2 51 ? 18.850 4.939 3.246 1.00 36.17 ? 51 THR U CB 1 ATOM 1381 O OG1 . THR B 2 51 ? 18.705 3.601 3.761 1.00 35.27 ? 51 THR U OG1 1 ATOM 1382 C CG2 . THR B 2 51 ? 20.345 5.236 2.990 1.00 35.45 ? 51 THR U CG2 1 ATOM 1383 N N . ASN B 2 52 ? 15.969 5.306 4.958 1.00 35.27 ? 52 ASN U N 1 ATOM 1384 C CA . ASN B 2 52 ? 15.077 4.473 5.749 1.00 35.36 ? 52 ASN U CA 1 ATOM 1385 C C . ASN B 2 52 ? 15.563 3.030 5.742 1.00 34.34 ? 52 ASN U C 1 ATOM 1386 O O . ASN B 2 52 ? 15.471 2.353 4.734 1.00 34.70 ? 52 ASN U O 1 ATOM 1387 C CB . ASN B 2 52 ? 13.598 4.681 5.377 1.00 35.77 ? 52 ASN U CB 1 ATOM 1388 C CG . ASN B 2 52 ? 13.178 6.104 5.625 1.00 40.38 ? 52 ASN U CG 1 ATOM 1389 O OD1 . ASN B 2 52 ? 13.936 6.840 6.211 1.00 44.25 ? 52 ASN U OD1 1 ATOM 1390 N ND2 . ASN B 2 52 ? 12.026 6.517 5.196 1.00 48.08 ? 52 ASN U ND2 1 ATOM 1391 N N . ARG B 2 53 ? 16.155 2.595 6.857 1.00 33.34 ? 53 ARG U N 1 ATOM 1392 C CA . ARG B 2 53 ? 16.784 1.277 6.933 1.00 32.29 ? 53 ARG U CA 1 ATOM 1393 C C . ARG B 2 53 ? 16.238 0.384 8.025 1.00 32.22 ? 53 ARG U C 1 ATOM 1394 O O . ARG B 2 53 ? 15.710 0.873 9.012 1.00 32.36 ? 53 ARG U O 1 ATOM 1395 C CB . ARG B 2 53 ? 18.291 1.397 7.070 1.00 31.64 ? 53 ARG U CB 1 ATOM 1396 C CG . ARG B 2 53 ? 18.736 1.921 8.372 1.00 30.62 ? 53 ARG U CG 1 ATOM 1397 C CD . ARG B 2 53 ? 20.211 2.229 8.327 1.00 29.06 ? 53 ARG U CD 1 ATOM 1398 N NE . ARG B 2 53 ? 20.529 3.249 7.326 1.00 26.05 ? 53 ARG U NE 1 ATOM 1399 C CZ . ARG B 2 53 ? 21.703 3.858 7.230 1.00 24.34 ? 53 ARG U CZ 1 ATOM 1400 N NH1 . ARG B 2 53 ? 22.670 3.576 8.074 1.00 24.99 ? 53 ARG U NH1 1 ATOM 1401 N NH2 . ARG B 2 53 ? 21.917 4.759 6.298 1.00 25.28 ? 53 ARG U NH2 1 ATOM 1402 N N . THR B 2 54 ? 16.409 -0.928 7.833 1.00 32.30 ? 54 THR U N 1 ATOM 1403 C CA . THR B 2 54 ? 15.846 -1.997 8.682 1.00 32.24 ? 54 THR U CA 1 ATOM 1404 C C . THR B 2 54 ? 16.757 -3.218 8.816 1.00 32.49 ? 54 THR U C 1 ATOM 1405 O O . THR B 2 54 ? 17.396 -3.610 7.852 1.00 32.75 ? 54 THR U O 1 ATOM 1406 C CB . THR B 2 54 ? 14.533 -2.453 8.106 1.00 31.93 ? 54 THR U CB 1 ATOM 1407 O OG1 . THR B 2 54 ? 13.563 -1.443 8.391 1.00 32.63 ? 54 THR U OG1 1 ATOM 1408 C CG2 . THR B 2 54 ? 14.092 -3.792 8.692 1.00 31.82 ? 54 THR U CG2 1 ATOM 1409 N N . MET B 2 55 ? 16.814 -3.807 10.013 1.00 32.86 ? 55 MET U N 1 ATOM 1410 C CA . MET B 2 55 ? 17.630 -4.993 10.283 1.00 33.12 ? 55 MET U CA 1 ATOM 1411 C C . MET B 2 55 ? 16.986 -5.758 11.389 1.00 32.83 ? 55 MET U C 1 ATOM 1412 O O . MET B 2 55 ? 16.393 -5.165 12.267 1.00 33.08 ? 55 MET U O 1 ATOM 1413 C CB . MET B 2 55 ? 19.055 -4.596 10.680 1.00 33.61 ? 55 MET U CB 1 ATOM 1414 C CG . MET B 2 55 ? 19.819 -5.584 11.579 1.00 35.65 ? 55 MET U CG 1 ATOM 1415 S SD . MET B 2 55 ? 21.649 -5.620 11.324 1.00 41.81 ? 55 MET U SD 1 ATOM 1416 C CE . MET B 2 55 ? 22.255 -3.982 11.770 1.00 39.56 ? 55 MET U CE 1 ATOM 1417 N N . SER B 2 56 ? 17.069 -7.079 11.328 1.00 33.04 ? 56 SER U N 1 ATOM 1418 C CA . SER B 2 56 ? 16.665 -7.945 12.451 1.00 33.08 ? 56 SER U CA 1 ATOM 1419 C C . SER B 2 56 ? 17.356 -9.287 12.373 1.00 32.72 ? 56 SER U C 1 ATOM 1420 O O . SER B 2 56 ? 17.669 -9.772 11.295 1.00 32.81 ? 56 SER U O 1 ATOM 1421 C CB . SER B 2 56 ? 15.143 -8.132 12.546 1.00 32.95 ? 56 SER U CB 1 ATOM 1422 O OG . SER B 2 56 ? 14.602 -8.533 11.305 1.00 33.57 ? 56 SER U OG 1 ATOM 1423 N N . TYR B 2 57 ? 17.606 -9.864 13.538 1.00 32.64 ? 57 TYR U N 1 ATOM 1424 C CA . TYR B 2 57 ? 18.253 -11.166 13.654 1.00 32.53 ? 57 TYR U CA 1 ATOM 1425 C C . TYR B 2 57 ? 17.896 -11.803 14.996 1.00 32.46 ? 57 TYR U C 1 ATOM 1426 O O . TYR B 2 57 ? 17.236 -11.174 15.834 1.00 32.45 ? 57 TYR U O 1 ATOM 1427 C CB . TYR B 2 57 ? 19.769 -11.040 13.482 1.00 32.30 ? 57 TYR U CB 1 ATOM 1428 C CG . TYR B 2 57 ? 20.513 -10.494 14.673 1.00 32.40 ? 57 TYR U CG 1 ATOM 1429 C CD1 . TYR B 2 57 ? 21.657 -11.131 15.144 1.00 32.63 ? 57 TYR U CD1 1 ATOM 1430 C CD2 . TYR B 2 57 ? 20.089 -9.340 15.324 1.00 32.84 ? 57 TYR U CD2 1 ATOM 1431 C CE1 . TYR B 2 57 ? 22.366 -10.637 16.229 1.00 33.41 ? 57 TYR U CE1 1 ATOM 1432 C CE2 . TYR B 2 57 ? 20.787 -8.839 16.418 1.00 34.14 ? 57 TYR U CE2 1 ATOM 1433 C CZ . TYR B 2 57 ? 21.928 -9.490 16.867 1.00 34.08 ? 57 TYR U CZ 1 ATOM 1434 O OH . TYR B 2 57 ? 22.616 -8.996 17.954 1.00 33.31 ? 57 TYR U OH 1 ATOM 1435 N N . ARG B 2 58 ? 18.298 -13.054 15.193 1.00 32.21 ? 58 ARG U N 1 ATOM 1436 C CA . ARG B 2 58 ? 18.122 -13.649 16.504 1.00 31.88 ? 58 ARG U CA 1 ATOM 1437 C C . ARG B 2 58 ? 19.375 -14.216 17.135 1.00 31.72 ? 58 ARG U C 1 ATOM 1438 O O . ARG B 2 58 ? 20.180 -14.905 16.510 1.00 31.94 ? 58 ARG U O 1 ATOM 1439 C CB . ARG B 2 58 ? 16.940 -14.621 16.585 1.00 31.98 ? 58 ARG U CB 1 ATOM 1440 C CG . ARG B 2 58 ? 16.606 -15.492 15.379 1.00 32.82 ? 58 ARG U CG 1 ATOM 1441 C CD . ARG B 2 58 ? 15.668 -16.600 15.892 1.00 34.88 ? 58 ARG U CD 1 ATOM 1442 N NE . ARG B 2 58 ? 14.907 -17.294 14.854 1.00 35.53 ? 58 ARG U NE 1 ATOM 1443 C CZ . ARG B 2 58 ? 14.337 -18.485 15.020 1.00 35.05 ? 58 ARG U CZ 1 ATOM 1444 N NH1 . ARG B 2 58 ? 14.445 -19.131 16.178 1.00 33.94 ? 58 ARG U NH1 1 ATOM 1445 N NH2 . ARG B 2 58 ? 13.669 -19.037 14.020 1.00 35.22 ? 58 ARG U NH2 1 ATOM 1446 N N . MET B 2 59 ? 19.529 -13.868 18.397 1.00 31.73 ? 59 MET U N 1 ATOM 1447 C CA . MET B 2 59 ? 20.559 -14.398 19.255 1.00 31.81 ? 59 MET U CA 1 ATOM 1448 C C . MET B 2 59 ? 19.809 -15.281 20.252 1.00 31.26 ? 59 MET U C 1 ATOM 1449 O O . MET B 2 59 ? 18.801 -14.856 20.827 1.00 31.17 ? 59 MET U O 1 ATOM 1450 C CB . MET B 2 59 ? 21.272 -13.228 19.941 1.00 31.90 ? 59 MET U CB 1 ATOM 1451 C CG . MET B 2 59 ? 22.258 -13.610 21.015 1.00 34.19 ? 59 MET U CG 1 ATOM 1452 S SD . MET B 2 59 ? 23.283 -12.238 21.624 1.00 38.99 ? 59 MET U SD 1 ATOM 1453 C CE . MET B 2 59 ? 24.500 -13.196 22.555 1.00 38.74 ? 59 MET U CE 1 ATOM 1454 N N . GLY B 2 60 ? 20.263 -16.513 20.433 1.00 30.71 ? 60 GLY U N 1 ATOM 1455 C CA . GLY B 2 60 ? 19.572 -17.423 21.329 1.00 30.84 ? 60 GLY U CA 1 ATOM 1456 C C . GLY B 2 60 ? 18.070 -17.390 21.107 1.00 31.18 ? 60 GLY U C 1 ATOM 1457 O O . GLY B 2 60 ? 17.605 -17.333 19.970 1.00 31.38 ? 60 GLY U O 1 ATOM 1458 N N . SER B 2 61 ? 17.308 -17.394 22.197 1.00 31.48 ? 61 SER U N 1 ATOM 1459 C CA . SER B 2 61 ? 15.845 -17.476 22.136 1.00 31.46 ? 61 SER U CA 1 ATOM 1460 C C . SER B 2 61 ? 15.137 -16.153 21.876 1.00 31.32 ? 61 SER U C 1 ATOM 1461 O O . SER B 2 61 ? 13.925 -16.082 22.064 1.00 30.80 ? 61 SER U O 1 ATOM 1462 C CB . SER B 2 61 ? 15.320 -18.007 23.461 1.00 31.77 ? 61 SER U CB 1 ATOM 1463 O OG . SER B 2 61 ? 15.294 -16.965 24.431 1.00 32.42 ? 61 SER U OG 1 ATOM 1464 N N . MET B 2 62 ? 15.885 -15.114 21.482 1.00 31.72 ? 62 MET U N 1 ATOM 1465 C CA . MET B 2 62 ? 15.322 -13.759 21.255 1.00 32.26 ? 62 MET U CA 1 ATOM 1466 C C . MET B 2 62 ? 15.488 -13.195 19.826 1.00 31.57 ? 62 MET U C 1 ATOM 1467 O O . MET B 2 62 ? 16.328 -13.667 19.069 1.00 31.77 ? 62 MET U O 1 ATOM 1468 C CB . MET B 2 62 ? 15.819 -12.745 22.317 1.00 32.76 ? 62 MET U CB 1 ATOM 1469 C CG . MET B 2 62 ? 17.232 -12.151 22.139 1.00 35.20 ? 62 MET U CG 1 ATOM 1470 S SD . MET B 2 62 ? 17.381 -10.352 22.570 1.00 41.54 ? 62 MET U SD 1 ATOM 1471 C CE . MET B 2 62 ? 16.658 -10.241 24.227 1.00 41.59 ? 62 MET U CE 1 ATOM 1472 N N . ILE B 2 63 ? 14.675 -12.201 19.466 1.00 30.68 ? 63 ILE U N 1 ATOM 1473 C CA . ILE B 2 63 ? 14.844 -11.493 18.201 1.00 30.13 ? 63 ILE U CA 1 ATOM 1474 C C . ILE B 2 63 ? 14.979 -10.026 18.490 1.00 29.90 ? 63 ILE U C 1 ATOM 1475 O O . ILE B 2 63 ? 14.096 -9.423 19.109 1.00 30.08 ? 63 ILE U O 1 ATOM 1476 C CB . ILE B 2 63 ? 13.611 -11.554 17.302 1.00 30.24 ? 63 ILE U CB 1 ATOM 1477 C CG1 . ILE B 2 63 ? 12.759 -12.775 17.621 1.00 31.42 ? 63 ILE U CG1 1 ATOM 1478 C CG2 . ILE B 2 63 ? 14.006 -11.453 15.838 1.00 28.93 ? 63 ILE U CG2 1 ATOM 1479 C CD1 . ILE B 2 63 ? 11.343 -12.395 17.964 1.00 33.43 ? 63 ILE U CD1 1 ATOM 1480 N N . ILE B 2 64 ? 16.065 -9.439 18.018 1.00 29.37 ? 64 ILE U N 1 ATOM 1481 C CA . ILE B 2 64 ? 16.209 -8.017 18.104 1.00 29.13 ? 64 ILE U CA 1 ATOM 1482 C C . ILE B 2 64 ? 15.855 -7.466 16.723 1.00 29.42 ? 64 ILE U C 1 ATOM 1483 O O . ILE B 2 64 ? 16.249 -8.037 15.702 1.00 29.83 ? 64 ILE U O 1 ATOM 1484 C CB . ILE B 2 64 ? 17.629 -7.613 18.572 1.00 29.05 ? 64 ILE U CB 1 ATOM 1485 C CG1 . ILE B 2 64 ? 18.413 -6.938 17.459 1.00 29.99 ? 64 ILE U CG1 1 ATOM 1486 C CG2 . ILE B 2 64 ? 18.409 -8.796 19.141 1.00 28.59 ? 64 ILE U CG2 1 ATOM 1487 C CD1 . ILE B 2 64 ? 18.065 -5.478 17.288 1.00 31.87 ? 64 ILE U CD1 1 ATOM 1488 N N . SER B 2 65 ? 15.096 -6.374 16.680 1.00 29.46 ? 65 SER U N 1 ATOM 1489 C CA . SER B 2 65 ? 14.731 -5.750 15.403 1.00 28.98 ? 65 SER U CA 1 ATOM 1490 C C . SER B 2 65 ? 14.954 -4.235 15.365 1.00 28.53 ? 65 SER U C 1 ATOM 1491 O O . SER B 2 65 ? 14.066 -3.448 15.739 1.00 27.84 ? 65 SER U O 1 ATOM 1492 C CB . SER B 2 65 ? 13.281 -6.067 15.066 1.00 29.27 ? 65 SER U CB 1 ATOM 1493 O OG . SER B 2 65 ? 12.414 -5.328 15.909 1.00 30.32 ? 65 SER U OG 1 ATOM 1494 N N . LEU B 2 66 ? 16.147 -3.857 14.905 1.00 28.16 ? 66 LEU U N 1 ATOM 1495 C CA . LEU B 2 66 ? 16.504 -2.480 14.571 1.00 28.33 ? 66 LEU U CA 1 ATOM 1496 C C . LEU B 2 66 ? 15.766 -1.910 13.310 1.00 29.00 ? 66 LEU U C 1 ATOM 1497 O O . LEU B 2 66 ? 15.524 -2.606 12.318 1.00 28.80 ? 66 LEU U O 1 ATOM 1498 C CB . LEU B 2 66 ? 18.019 -2.402 14.378 1.00 28.08 ? 66 LEU U CB 1 ATOM 1499 C CG . LEU B 2 66 ? 18.979 -3.034 15.404 1.00 27.79 ? 66 LEU U CG 1 ATOM 1500 C CD1 . LEU B 2 66 ? 20.200 -3.698 14.830 1.00 26.29 ? 66 LEU U CD1 1 ATOM 1501 C CD2 . LEU B 2 66 ? 19.462 -2.021 16.365 1.00 29.91 ? 66 LEU U CD2 1 ATOM 1502 N N . THR B 2 67 ? 15.379 -0.640 13.387 1.00 29.91 ? 67 THR U N 1 ATOM 1503 C CA . THR B 2 67 ? 14.757 0.094 12.276 1.00 30.72 ? 67 THR U CA 1 ATOM 1504 C C . THR B 2 67 ? 15.146 1.564 12.399 1.00 31.61 ? 67 THR U C 1 ATOM 1505 O O . THR B 2 67 ? 15.219 2.093 13.513 1.00 32.02 ? 67 THR U O 1 ATOM 1506 C CB . THR B 2 67 ? 13.185 0.069 12.269 1.00 30.75 ? 67 THR U CB 1 ATOM 1507 O OG1 . THR B 2 67 ? 12.674 1.282 12.849 1.00 29.87 ? 67 THR U OG1 1 ATOM 1508 C CG2 . THR B 2 67 ? 12.585 -1.169 12.961 1.00 30.51 ? 67 THR U CG2 1 ATOM 1509 N N . GLU B 2 68 ? 15.373 2.225 11.266 1.00 32.33 ? 68 GLU U N 1 ATOM 1510 C CA . GLU B 2 68 ? 15.662 3.658 11.266 1.00 33.04 ? 68 GLU U CA 1 ATOM 1511 C C . GLU B 2 68 ? 14.782 4.406 10.263 1.00 32.89 ? 68 GLU U C 1 ATOM 1512 O O . GLU B 2 68 ? 14.516 3.902 9.181 1.00 33.00 ? 68 GLU U O 1 ATOM 1513 C CB . GLU B 2 68 ? 17.141 3.906 10.993 1.00 33.11 ? 68 GLU U CB 1 ATOM 1514 C CG . GLU B 2 68 ? 17.702 5.056 11.810 1.00 34.80 ? 68 GLU U CG 1 ATOM 1515 C CD . GLU B 2 68 ? 19.233 5.113 11.791 1.00 37.61 ? 68 GLU U CD 1 ATOM 1516 O OE1 . GLU B 2 68 ? 19.846 4.855 12.860 1.00 38.83 ? 68 GLU U OE1 1 ATOM 1517 O OE2 . GLU B 2 68 ? 19.823 5.418 10.720 1.00 37.11 ? 68 GLU U OE2 1 ATOM 1518 N N . THR B 2 69 ? 14.330 5.603 10.635 1.00 32.73 ? 69 THR U N 1 ATOM 1519 C CA . THR B 2 69 ? 13.386 6.358 9.823 1.00 32.25 ? 69 THR U CA 1 ATOM 1520 C C . THR B 2 69 ? 13.676 7.837 9.847 1.00 32.01 ? 69 THR U C 1 ATOM 1521 O O . THR B 2 69 ? 13.789 8.438 10.904 1.00 32.06 ? 69 THR U O 1 ATOM 1522 C CB . THR B 2 69 ? 11.946 6.108 10.261 1.00 32.13 ? 69 THR U CB 1 ATOM 1523 O OG1 . THR B 2 69 ? 11.463 4.945 9.588 1.00 32.61 ? 69 THR U OG1 1 ATOM 1524 C CG2 . THR B 2 69 ? 11.057 7.272 9.888 1.00 33.03 ? 69 THR U CG2 1 ATOM 1525 N N . VAL B 2 70 ? 13.752 8.419 8.659 1.00 31.92 ? 70 VAL U N 1 ATOM 1526 C CA . VAL B 2 70 ? 14.166 9.797 8.491 1.00 31.66 ? 70 VAL U CA 1 ATOM 1527 C C . VAL B 2 70 ? 13.180 10.626 7.640 1.00 31.90 ? 70 VAL U C 1 ATOM 1528 O O . VAL B 2 70 ? 12.462 10.092 6.799 1.00 31.65 ? 70 VAL U O 1 ATOM 1529 C CB . VAL B 2 70 ? 15.608 9.838 7.947 1.00 31.43 ? 70 VAL U CB 1 ATOM 1530 C CG1 . VAL B 2 70 ? 16.486 8.922 8.764 1.00 30.97 ? 70 VAL U CG1 1 ATOM 1531 C CG2 . VAL B 2 70 ? 15.671 9.390 6.504 1.00 31.74 ? 70 VAL U CG2 1 ATOM 1532 N N . CYS B 2 71 ? 13.136 11.929 7.912 1.00 32.64 ? 71 CYS U N 1 ATOM 1533 C CA . CYS B 2 71 ? 12.354 12.916 7.141 1.00 33.72 ? 71 CYS U CA 1 ATOM 1534 C C . CYS B 2 71 ? 12.879 14.340 7.327 1.00 33.67 ? 71 CYS U C 1 ATOM 1535 O O . CYS B 2 71 ? 13.453 14.683 8.377 1.00 33.70 ? 71 CYS U O 1 ATOM 1536 C CB . CYS B 2 71 ? 10.895 12.901 7.537 1.00 33.75 ? 71 CYS U CB 1 ATOM 1537 S SG . CYS B 2 71 ? 10.751 12.718 9.281 1.00 37.58 ? 71 CYS U SG 1 ATOM 1538 N N . ALA B 2 72 ? 12.652 15.163 6.298 1.00 33.66 ? 72 ALA U N 1 ATOM 1539 C CA . ALA B 2 72 ? 13.219 16.505 6.222 1.00 33.29 ? 72 ALA U CA 1 ATOM 1540 C C . ALA B 2 72 ? 12.216 17.621 6.547 1.00 33.01 ? 72 ALA U C 1 ATOM 1541 O O . ALA B 2 72 ? 12.299 18.707 5.972 1.00 33.01 ? 72 ALA U O 1 ATOM 1542 C CB . ALA B 2 72 ? 13.886 16.733 4.859 1.00 32.82 ? 72 ALA U CB 1 ATOM 1543 N N . THR B 2 73 ? 11.290 17.369 7.473 1.00 32.58 ? 73 THR U N 1 ATOM 1544 C CA . THR B 2 73 ? 10.403 18.443 7.941 1.00 32.52 ? 73 THR U CA 1 ATOM 1545 C C . THR B 2 73 ? 10.461 18.717 9.450 1.00 32.84 ? 73 THR U C 1 ATOM 1546 O O . THR B 2 73 ? 11.079 17.960 10.225 1.00 32.94 ? 73 THR U O 1 ATOM 1547 C CB . THR B 2 73 ? 8.957 18.240 7.521 1.00 32.12 ? 73 THR U CB 1 ATOM 1548 O OG1 . THR B 2 73 ? 8.562 16.909 7.848 1.00 32.13 ? 73 THR U OG1 1 ATOM 1549 C CG2 . THR B 2 73 ? 8.814 18.462 6.037 1.00 32.01 ? 73 THR U CG2 1 ATOM 1550 N N . ASN B 2 74 ? 9.811 19.809 9.854 1.00 32.66 ? 74 ASN U N 1 ATOM 1551 C CA . ASN B 2 74 ? 9.934 20.300 11.216 1.00 32.55 ? 74 ASN U CA 1 ATOM 1552 C C . ASN B 2 74 ? 9.317 19.438 12.303 1.00 32.85 ? 74 ASN U C 1 ATOM 1553 O O . ASN B 2 74 ? 8.081 19.382 12.440 1.00 32.92 ? 74 ASN U O 1 ATOM 1554 C CB . ASN B 2 74 ? 9.442 21.735 11.319 1.00 32.30 ? 74 ASN U CB 1 ATOM 1555 C CG . ASN B 2 74 ? 10.537 22.721 11.040 1.00 32.13 ? 74 ASN U CG 1 ATOM 1556 O OD1 . ASN B 2 74 ? 11.614 22.330 10.602 1.00 31.80 ? 74 ASN U OD1 1 ATOM 1557 N ND2 . ASN B 2 74 ? 10.286 24.008 11.303 1.00 31.97 ? 74 ASN U ND2 1 ATOM 1558 N N . LEU B 2 75 ? 10.212 18.787 13.065 1.00 32.87 ? 75 LEU U N 1 ATOM 1559 C CA . LEU B 2 75 ? 9.899 17.895 14.200 1.00 32.76 ? 75 LEU U CA 1 ATOM 1560 C C . LEU B 2 75 ? 9.053 16.730 13.760 1.00 33.21 ? 75 LEU U C 1 ATOM 1561 O O . LEU B 2 75 ? 8.010 16.439 14.343 1.00 32.79 ? 75 LEU U O 1 ATOM 1562 C CB . LEU B 2 75 ? 9.219 18.629 15.358 1.00 32.56 ? 75 LEU U CB 1 ATOM 1563 C CG . LEU B 2 75 ? 9.762 19.970 15.847 1.00 32.23 ? 75 LEU U CG 1 ATOM 1564 C CD1 . LEU B 2 75 ? 8.937 20.440 17.027 1.00 31.27 ? 75 LEU U CD1 1 ATOM 1565 C CD2 . LEU B 2 75 ? 11.221 19.875 16.212 1.00 31.80 ? 75 LEU U CD2 1 ATOM 1566 N N . CYS B 2 76 ? 9.521 16.068 12.709 1.00 34.17 ? 76 CYS U N 1 ATOM 1567 C CA . CYS B 2 76 ? 8.783 14.981 12.112 1.00 34.93 ? 76 CYS U CA 1 ATOM 1568 C C . CYS B 2 76 ? 9.045 13.660 12.835 1.00 35.00 ? 76 CYS U C 1 ATOM 1569 O O . CYS B 2 76 ? 8.409 12.666 12.523 1.00 35.26 ? 76 CYS U O 1 ATOM 1570 C CB . CYS B 2 76 ? 9.080 14.907 10.616 1.00 35.14 ? 76 CYS U CB 1 ATOM 1571 S SG . CYS B 2 76 ? 10.846 14.616 10.100 1.00 38.22 ? 76 CYS U SG 1 ATOM 1572 N N . ASN B 2 77 ? 9.991 13.651 13.777 1.00 35.07 ? 77 ASN U N 1 ATOM 1573 C CA . ASN B 2 77 ? 10.083 12.604 14.791 1.00 35.36 ? 77 ASN U CA 1 ATOM 1574 C C . ASN B 2 77 ? 9.294 13.085 15.992 1.00 36.50 ? 77 ASN U C 1 ATOM 1575 O O . ASN B 2 77 ? 9.334 14.263 16.265 1.00 36.97 ? 77 ASN U O 1 ATOM 1576 C CB . ASN B 2 77 ? 11.538 12.351 15.179 1.00 34.76 ? 77 ASN U CB 1 ATOM 1577 C CG . ASN B 2 77 ? 12.397 13.592 15.118 1.00 32.96 ? 77 ASN U CG 1 ATOM 1578 O OD1 . ASN B 2 77 ? 11.901 14.682 14.923 1.00 30.68 ? 77 ASN U OD1 1 ATOM 1579 N ND2 . ASN B 2 77 ? 13.704 13.422 15.278 1.00 31.61 ? 77 ASN U ND2 1 ATOM 1580 N N . ARG B 2 78 ? 8.559 12.234 16.711 1.00 37.85 ? 78 ARG U N 1 ATOM 1581 C CA . ARG B 2 78 ? 7.734 12.787 17.807 1.00 39.24 ? 78 ARG U CA 1 ATOM 1582 C C . ARG B 2 78 ? 7.471 11.966 19.103 1.00 41.11 ? 78 ARG U C 1 ATOM 1583 O O . ARG B 2 78 ? 8.409 11.684 19.844 1.00 40.60 ? 78 ARG U O 1 ATOM 1584 C CB . ARG B 2 78 ? 6.461 13.432 17.244 1.00 38.83 ? 78 ARG U CB 1 ATOM 1585 C CG . ARG B 2 78 ? 6.651 14.831 16.698 1.00 37.29 ? 78 ARG U CG 1 ATOM 1586 C CD . ARG B 2 78 ? 6.375 15.894 17.726 1.00 36.24 ? 78 ARG U CD 1 ATOM 1587 N NE . ARG B 2 78 ? 4.996 16.380 17.654 1.00 36.14 ? 78 ARG U NE 1 ATOM 1588 C CZ . ARG B 2 78 ? 4.414 17.153 18.571 1.00 35.89 ? 78 ARG U CZ 1 ATOM 1589 N NH1 . ARG B 2 78 ? 5.083 17.537 19.652 1.00 36.36 ? 78 ARG U NH1 1 ATOM 1590 N NH2 . ARG B 2 78 ? 3.155 17.541 18.411 1.00 35.05 ? 78 ARG U NH2 1 ATOM 1591 N N . PRO B 2 79 ? 6.200 11.605 19.409 1.00 43.31 ? 79 PRO U N 1 ATOM 1592 C CA . PRO B 2 79 ? 6.009 10.956 20.715 1.00 45.17 ? 79 PRO U CA 1 ATOM 1593 C C . PRO B 2 79 ? 6.043 9.412 20.639 1.00 47.30 ? 79 PRO U C 1 ATOM 1594 O O . PRO B 2 79 ? 6.904 8.756 21.278 1.00 47.55 ? 79 PRO U O 1 ATOM 1595 C CB . PRO B 2 79 ? 4.604 11.443 21.143 1.00 44.80 ? 79 PRO U CB 1 ATOM 1596 C CG . PRO B 2 79 ? 3.909 11.897 19.857 1.00 43.88 ? 79 PRO U CG 1 ATOM 1597 C CD . PRO B 2 79 ? 4.905 11.779 18.716 1.00 43.52 ? 79 PRO U CD 1 ATOM 1598 N N . ARG B 2 80 ? 5.083 8.870 19.872 1.00 49.21 ? 80 ARG U N 1 ATOM 1599 C CA . ARG B 2 80 ? 4.910 7.447 19.594 1.00 50.73 ? 80 ARG U CA 1 ATOM 1600 C C . ARG B 2 80 ? 6.110 6.963 18.746 1.00 51.53 ? 80 ARG U C 1 ATOM 1601 O O . ARG B 2 80 ? 6.865 7.811 18.258 1.00 51.79 ? 80 ARG U O 1 ATOM 1602 C CB . ARG B 2 80 ? 3.564 7.260 18.865 1.00 51.02 ? 80 ARG U CB 1 ATOM 1603 C CG . ARG B 2 80 ? 2.302 7.339 19.759 1.00 51.97 ? 80 ARG U CG 1 ATOM 1604 C CD . ARG B 2 80 ? 2.145 6.055 20.608 1.00 54.22 ? 80 ARG U CD 1 ATOM 1605 N NE . ARG B 2 80 ? 0.754 5.648 20.886 1.00 54.51 ? 80 ARG U NE 1 ATOM 1606 C CZ . ARG B 2 80 ? 0.062 4.763 20.163 1.00 54.21 ? 80 ARG U CZ 1 ATOM 1607 N NH1 . ARG B 2 80 ? 0.615 4.198 19.088 1.00 53.89 ? 80 ARG U NH1 1 ATOM 1608 N NH2 . ARG B 2 80 ? -1.187 4.454 20.508 1.00 52.59 ? 80 ARG U NH2 1 ATOM 1609 N N . PRO B 2 81 ? 6.301 5.617 18.568 1.00 52.28 ? 81 PRO U N 1 ATOM 1610 C CA . PRO B 2 81 ? 7.543 5.113 17.898 1.00 52.39 ? 81 PRO U CA 1 ATOM 1611 C C . PRO B 2 81 ? 7.642 5.413 16.394 1.00 52.38 ? 81 PRO U C 1 ATOM 1612 O O . PRO B 2 81 ? 6.642 5.316 15.673 1.00 52.49 ? 81 PRO U O 1 ATOM 1613 C CB . PRO B 2 81 ? 7.490 3.592 18.135 1.00 52.54 ? 81 PRO U CB 1 ATOM 1614 C CG . PRO B 2 81 ? 6.000 3.274 18.289 1.00 52.44 ? 81 PRO U CG 1 ATOM 1615 C CD . PRO B 2 81 ? 5.379 4.508 18.931 1.00 52.41 ? 81 PRO U CD 1 ATOM 1616 N N . TYR B 2 93 ? 7.891 -11.896 3.178 1.00 32.83 ? 93 TYR U N 1 ATOM 1617 C CA . TYR B 2 93 ? 8.743 -12.866 3.873 1.00 33.18 ? 93 TYR U CA 1 ATOM 1618 C C . TYR B 2 93 ? 9.658 -13.650 2.949 1.00 33.14 ? 93 TYR U C 1 ATOM 1619 O O . TYR B 2 93 ? 9.255 -14.058 1.861 1.00 33.56 ? 93 TYR U O 1 ATOM 1620 C CB . TYR B 2 93 ? 7.923 -13.893 4.648 1.00 33.34 ? 93 TYR U CB 1 ATOM 1621 C CG . TYR B 2 93 ? 6.433 -13.713 4.610 1.00 34.44 ? 93 TYR U CG 1 ATOM 1622 C CD1 . TYR B 2 93 ? 5.763 -13.121 5.688 1.00 35.12 ? 93 TYR U CD1 1 ATOM 1623 C CD2 . TYR B 2 93 ? 5.680 -14.166 3.507 1.00 33.80 ? 93 TYR U CD2 1 ATOM 1624 C CE1 . TYR B 2 93 ? 4.382 -12.960 5.660 1.00 36.08 ? 93 TYR U CE1 1 ATOM 1625 C CE2 . TYR B 2 93 ? 4.302 -14.011 3.467 1.00 34.01 ? 93 TYR U CE2 1 ATOM 1626 C CZ . TYR B 2 93 ? 3.656 -13.405 4.544 1.00 35.39 ? 93 TYR U CZ 1 ATOM 1627 O OH . TYR B 2 93 ? 2.288 -13.241 4.525 1.00 35.28 ? 93 TYR U OH 1 ATOM 1628 N N . LEU B 2 94 ? 10.871 -13.907 3.422 1.00 33.08 ? 94 LEU U N 1 ATOM 1629 C CA . LEU B 2 94 ? 11.907 -14.611 2.669 1.00 33.37 ? 94 LEU U CA 1 ATOM 1630 C C . LEU B 2 94 ? 12.964 -15.077 3.664 1.00 34.02 ? 94 LEU U C 1 ATOM 1631 O O . LEU B 2 94 ? 13.441 -14.277 4.468 1.00 34.66 ? 94 LEU U O 1 ATOM 1632 C CB . LEU B 2 94 ? 12.532 -13.667 1.621 1.00 33.01 ? 94 LEU U CB 1 ATOM 1633 C CG . LEU B 2 94 ? 13.968 -13.877 1.121 1.00 31.92 ? 94 LEU U CG 1 ATOM 1634 C CD1 . LEU B 2 94 ? 14.092 -15.163 0.319 1.00 31.86 ? 94 LEU U CD1 1 ATOM 1635 C CD2 . LEU B 2 94 ? 14.441 -12.687 0.305 1.00 30.01 ? 94 LEU U CD2 1 ATOM 1636 N N . GLU B 2 95 ? 13.348 -16.348 3.622 1.00 34.53 ? 95 GLU U N 1 ATOM 1637 C CA . GLU B 2 95 ? 14.258 -16.882 4.642 1.00 35.28 ? 95 GLU U CA 1 ATOM 1638 C C . GLU B 2 95 ? 15.765 -16.657 4.442 1.00 35.61 ? 95 GLU U C 1 ATOM 1639 O O . GLU B 2 95 ? 16.300 -16.816 3.346 1.00 35.02 ? 95 GLU U O 1 ATOM 1640 C CB . GLU B 2 95 ? 13.981 -18.357 4.915 1.00 35.54 ? 95 GLU U CB 1 ATOM 1641 C CG . GLU B 2 95 ? 13.246 -18.631 6.232 1.00 36.67 ? 95 GLU U CG 1 ATOM 1642 C CD . GLU B 2 95 ? 12.885 -20.119 6.435 1.00 39.05 ? 95 GLU U CD 1 ATOM 1643 O OE1 . GLU B 2 95 ? 12.115 -20.420 7.382 1.00 38.93 ? 95 GLU U OE1 1 ATOM 1644 O OE2 . GLU B 2 95 ? 13.361 -20.985 5.648 1.00 39.72 ? 95 GLU U OE2 1 ATOM 1645 N N . CYS B 2 96 ? 16.419 -16.287 5.551 1.00 36.61 ? 96 CYS U N 1 ATOM 1646 C CA . CYS B 2 96 ? 17.866 -16.037 5.644 1.00 37.21 ? 96 CYS U CA 1 ATOM 1647 C C . CYS B 2 96 ? 18.395 -16.567 6.960 1.00 37.01 ? 96 CYS U C 1 ATOM 1648 O O . CYS B 2 96 ? 17.710 -16.484 7.981 1.00 36.69 ? 96 CYS U O 1 ATOM 1649 C CB . CYS B 2 96 ? 18.165 -14.541 5.599 1.00 37.40 ? 96 CYS U CB 1 ATOM 1650 S SG . CYS B 2 96 ? 17.118 -13.548 4.487 1.00 40.01 ? 96 CYS U SG 1 ATOM 1651 N N . ALA B 2 97 ? 19.622 -17.082 6.931 1.00 37.26 ? 97 ALA U N 1 ATOM 1652 C CA . ALA B 2 97 ? 20.284 -17.615 8.126 1.00 37.89 ? 97 ALA U CA 1 ATOM 1653 C C . ALA B 2 97 ? 20.515 -16.526 9.181 1.00 38.11 ? 97 ALA U C 1 ATOM 1654 O O . ALA B 2 97 ? 20.782 -15.388 8.827 1.00 38.48 ? 97 ALA U O 1 ATOM 1655 C CB . ALA B 2 97 ? 21.606 -18.262 7.741 1.00 37.78 ? 97 ALA U CB 1 ATOM 1656 N N . SER B 2 98 ? 20.408 -16.860 10.465 1.00 38.23 ? 98 SER U N 1 ATOM 1657 C CA . SER B 2 98 ? 20.706 -15.879 11.519 1.00 38.56 ? 98 SER U CA 1 ATOM 1658 C C . SER B 2 98 ? 21.572 -16.399 12.647 1.00 38.81 ? 98 SER U C 1 ATOM 1659 O O . SER B 2 98 ? 21.746 -17.597 12.800 1.00 39.06 ? 98 SER U O 1 ATOM 1660 C CB . SER B 2 98 ? 19.432 -15.287 12.100 1.00 38.61 ? 98 SER U CB 1 ATOM 1661 O OG . SER B 2 98 ? 19.009 -14.191 11.319 1.00 39.10 ? 98 SER U OG 1 ATOM 1662 N N . CYS B 2 99 ? 22.102 -15.490 13.448 1.00 39.08 ? 99 CYS U N 1 ATOM 1663 C CA . CYS B 2 99 ? 23.090 -15.833 14.438 1.00 40.15 ? 99 CYS U CA 1 ATOM 1664 C C . CYS B 2 99 ? 23.895 -14.593 14.628 1.00 39.64 ? 99 CYS U C 1 ATOM 1665 O O . CYS B 2 99 ? 23.905 -13.750 13.757 1.00 39.66 ? 99 CYS U O 1 ATOM 1666 C CB . CYS B 2 99 ? 24.044 -16.862 13.875 1.00 40.71 ? 99 CYS U CB 1 ATOM 1667 S SG . CYS B 2 99 ? 24.823 -16.233 12.375 1.00 46.34 ? 99 CYS U SG 1 ATOM 1668 N N . THR B 2 100 ? 24.614 -14.511 15.741 1.00 39.75 ? 100 THR U N 1 ATOM 1669 C CA . THR B 2 100 ? 25.560 -13.436 15.986 1.00 39.68 ? 100 THR U CA 1 ATOM 1670 C C . THR B 2 100 ? 26.891 -14.044 16.330 1.00 40.21 ? 100 THR U C 1 ATOM 1671 O O . THR B 2 100 ? 26.945 -15.195 16.743 1.00 40.29 ? 100 THR U O 1 ATOM 1672 C CB . THR B 2 100 ? 25.122 -12.558 17.145 1.00 39.31 ? 100 THR U CB 1 ATOM 1673 O OG1 . THR B 2 100 ? 26.271 -11.965 17.752 1.00 39.40 ? 100 THR U OG1 1 ATOM 1674 C CG2 . THR B 2 100 ? 24.424 -13.363 18.166 1.00 38.77 ? 100 THR U CG2 1 ATOM 1675 N N . SER B 2 101 ? 27.964 -13.279 16.148 1.00 40.98 ? 101 SER U N 1 ATOM 1676 C CA . SER B 2 101 ? 29.267 -13.675 16.660 1.00 41.70 ? 101 SER U CA 1 ATOM 1677 C C . SER B 2 101 ? 29.188 -13.803 18.185 1.00 42.44 ? 101 SER U C 1 ATOM 1678 O O . SER B 2 101 ? 29.690 -14.781 18.749 1.00 42.93 ? 101 SER U O 1 ATOM 1679 C CB . SER B 2 101 ? 30.339 -12.659 16.293 1.00 41.52 ? 101 SER U CB 1 ATOM 1680 O OG . SER B 2 101 ? 30.555 -11.776 17.380 1.00 41.81 ? 101 SER U OG 1 ATOM 1681 N N . LEU B 2 102 ? 28.541 -12.833 18.835 1.00 42.89 ? 102 LEU U N 1 ATOM 1682 C CA . LEU B 2 102 ? 28.380 -12.814 20.289 1.00 43.85 ? 102 LEU U CA 1 ATOM 1683 C C . LEU B 2 102 ? 28.011 -14.119 21.036 1.00 44.66 ? 102 LEU U C 1 ATOM 1684 O O . LEU B 2 102 ? 28.617 -14.442 22.073 1.00 45.07 ? 102 LEU U O 1 ATOM 1685 C CB . LEU B 2 102 ? 27.386 -11.736 20.671 1.00 43.63 ? 102 LEU U CB 1 ATOM 1686 C CG . LEU B 2 102 ? 27.495 -11.365 22.145 1.00 44.49 ? 102 LEU U CG 1 ATOM 1687 C CD1 . LEU B 2 102 ? 28.842 -10.668 22.495 1.00 44.96 ? 102 LEU U CD1 1 ATOM 1688 C CD2 . LEU B 2 102 ? 26.319 -10.499 22.530 1.00 45.70 ? 102 LEU U CD2 1 ATOM 1689 N N . ASP B 2 103 ? 27.026 -14.864 20.540 1.00 45.30 ? 103 ASP U N 1 ATOM 1690 C CA . ASP B 2 103 ? 26.632 -16.112 21.199 1.00 46.09 ? 103 ASP U CA 1 ATOM 1691 C C . ASP B 2 103 ? 27.325 -17.346 20.629 1.00 46.27 ? 103 ASP U C 1 ATOM 1692 O O . ASP B 2 103 ? 26.868 -18.469 20.850 1.00 46.36 ? 103 ASP U O 1 ATOM 1693 C CB . ASP B 2 103 ? 25.113 -16.297 21.150 1.00 46.39 ? 103 ASP U CB 1 ATOM 1694 C CG . ASP B 2 103 ? 24.574 -16.356 19.728 1.00 48.09 ? 103 ASP U CG 1 ATOM 1695 O OD1 . ASP B 2 103 ? 25.340 -16.039 18.789 1.00 50.00 ? 103 ASP U OD1 1 ATOM 1696 O OD2 . ASP B 2 103 ? 23.381 -16.707 19.540 1.00 49.67 ? 103 ASP U OD2 1 ATOM 1697 N N . GLN B 2 104 ? 28.424 -17.133 19.906 1.00 46.68 ? 104 GLN U N 1 ATOM 1698 C CA . GLN B 2 104 ? 29.197 -18.210 19.257 1.00 47.43 ? 104 GLN U CA 1 ATOM 1699 C C . GLN B 2 104 ? 28.343 -19.117 18.345 1.00 47.53 ? 104 GLN U C 1 ATOM 1700 O O . GLN B 2 104 ? 28.514 -20.342 18.328 1.00 47.44 ? 104 GLN U O 1 ATOM 1701 C CB . GLN B 2 104 ? 29.978 -19.065 20.285 1.00 47.62 ? 104 GLN U CB 1 ATOM 1702 C CG . GLN B 2 104 ? 30.536 -18.337 21.526 1.00 48.86 ? 104 GLN U CG 1 ATOM 1703 C CD . GLN B 2 104 ? 31.656 -17.342 21.220 1.00 50.20 ? 104 GLN U CD 1 ATOM 1704 O OE1 . GLN B 2 104 ? 32.180 -17.293 20.095 1.00 50.50 ? 104 GLN U OE1 1 ATOM 1705 N NE2 . GLN B 2 104 ? 32.026 -16.537 22.230 1.00 49.06 ? 104 GLN U NE2 1 ATOM 1706 N N . SER B 2 105 ? 27.439 -18.514 17.580 1.00 47.73 ? 105 SER U N 1 ATOM 1707 C CA . SER B 2 105 ? 26.543 -19.286 16.734 1.00 48.25 ? 105 SER U CA 1 ATOM 1708 C C . SER B 2 105 ? 26.823 -19.146 15.237 1.00 48.97 ? 105 SER U C 1 ATOM 1709 O O . SER B 2 105 ? 26.588 -20.077 14.480 1.00 49.04 ? 105 SER U O 1 ATOM 1710 C CB . SER B 2 105 ? 25.108 -18.924 17.031 1.00 47.88 ? 105 SER U CB 1 ATOM 1711 O OG . SER B 2 105 ? 24.927 -17.553 16.798 1.00 47.35 ? 105 SER U OG 1 ATOM 1712 N N . CYS B 2 106 ? 27.332 -17.994 14.809 1.00 49.99 ? 106 CYS U N 1 ATOM 1713 C CA . CYS B 2 106 ? 27.719 -17.808 13.396 1.00 50.95 ? 106 CYS U CA 1 ATOM 1714 C C . CYS B 2 106 ? 29.006 -18.558 13.058 1.00 51.62 ? 106 CYS U C 1 ATOM 1715 O O . CYS B 2 106 ? 29.306 -18.768 11.886 1.00 51.68 ? 106 CYS U O 1 ATOM 1716 C CB . CYS B 2 106 ? 27.906 -16.317 13.020 1.00 50.83 ? 106 CYS U CB 1 ATOM 1717 S SG . CYS B 2 106 ? 26.443 -15.142 13.003 1.00 50.94 ? 106 CYS U SG 1 ATOM 1718 N N . GLU B 2 107 ? 29.766 -18.942 14.085 1.00 52.70 ? 107 GLU U N 1 ATOM 1719 C CA . GLU B 2 107 ? 31.077 -19.585 13.898 1.00 53.80 ? 107 GLU U CA 1 ATOM 1720 C C . GLU B 2 107 ? 30.972 -21.096 13.770 1.00 53.85 ? 107 GLU U C 1 ATOM 1721 O O . GLU B 2 107 ? 31.788 -21.724 13.077 1.00 54.23 ? 107 GLU U O 1 ATOM 1722 C CB . GLU B 2 107 ? 32.052 -19.235 15.029 1.00 54.07 ? 107 GLU U CB 1 ATOM 1723 C CG . GLU B 2 107 ? 32.574 -17.796 14.994 1.00 56.31 ? 107 GLU U CG 1 ATOM 1724 C CD . GLU B 2 107 ? 31.577 -16.760 15.552 1.00 58.98 ? 107 GLU U CD 1 ATOM 1725 O OE1 . GLU B 2 107 ? 30.701 -17.124 16.384 1.00 59.93 ? 107 GLU U OE1 1 ATOM 1726 O OE2 . GLU B 2 107 ? 31.687 -15.572 15.159 1.00 59.33 ? 107 GLU U OE2 1 ATOM 1727 N N . ARG B 2 108 ? 29.979 -21.677 14.441 1.00 53.71 ? 108 ARG U N 1 ATOM 1728 C CA . ARG B 2 108 ? 29.741 -23.112 14.332 1.00 53.72 ? 108 ARG U CA 1 ATOM 1729 C C . ARG B 2 108 ? 28.885 -23.454 13.095 1.00 53.45 ? 108 ARG U C 1 ATOM 1730 O O . ARG B 2 108 ? 27.940 -22.721 12.767 1.00 53.34 ? 108 ARG U O 1 ATOM 1731 C CB . ARG B 2 108 ? 29.136 -23.665 15.634 1.00 53.79 ? 108 ARG U CB 1 ATOM 1732 C CG . ARG B 2 108 ? 30.133 -23.718 16.806 1.00 54.20 ? 108 ARG U CG 1 ATOM 1733 C CD . ARG B 2 108 ? 31.091 -24.931 16.746 1.00 54.31 ? 108 ARG U CD 1 ATOM 1734 N NE . ARG B 2 108 ? 30.790 -25.914 17.789 1.00 54.12 ? 108 ARG U NE 1 ATOM 1735 C CZ . ARG B 2 108 ? 31.376 -25.961 18.989 1.00 54.06 ? 108 ARG U CZ 1 ATOM 1736 N NH1 . ARG B 2 108 ? 32.321 -25.089 19.321 1.00 53.69 ? 108 ARG U NH1 1 ATOM 1737 N NH2 . ARG B 2 108 ? 31.015 -26.892 19.866 1.00 53.89 ? 108 ARG U NH2 1 ATOM 1738 N N . GLY B 2 109 ? 29.244 -24.546 12.406 1.00 52.98 ? 109 GLY U N 1 ATOM 1739 C CA . GLY B 2 109 ? 28.464 -25.080 11.285 1.00 52.32 ? 109 GLY U CA 1 ATOM 1740 C C . GLY B 2 109 ? 27.034 -25.436 11.678 1.00 52.00 ? 109 GLY U C 1 ATOM 1741 O O . GLY B 2 109 ? 26.590 -26.571 11.464 1.00 52.08 ? 109 GLY U O 1 ATOM 1742 N N . ARG B 2 110 ? 26.343 -24.451 12.271 1.00 51.38 ? 110 ARG U N 1 ATOM 1743 C CA . ARG B 2 110 ? 24.911 -24.464 12.631 1.00 50.95 ? 110 ARG U CA 1 ATOM 1744 C C . ARG B 2 110 ? 24.535 -23.036 13.108 1.00 50.38 ? 110 ARG U C 1 ATOM 1745 O O . ARG B 2 110 ? 25.377 -22.363 13.707 1.00 50.84 ? 110 ARG U O 1 ATOM 1746 C CB . ARG B 2 110 ? 24.592 -25.538 13.697 1.00 50.94 ? 110 ARG U CB 1 ATOM 1747 C CG . ARG B 2 110 ? 25.115 -25.263 15.112 1.00 52.14 ? 110 ARG U CG 1 ATOM 1748 C CD . ARG B 2 110 ? 24.073 -24.522 15.974 1.00 54.24 ? 110 ARG U CD 1 ATOM 1749 N NE . ARG B 2 110 ? 24.673 -23.626 16.968 1.00 55.88 ? 110 ARG U NE 1 ATOM 1750 C CZ . ARG B 2 110 ? 25.103 -24.003 18.177 1.00 57.45 ? 110 ARG U CZ 1 ATOM 1751 N NH1 . ARG B 2 110 ? 25.024 -25.280 18.571 1.00 57.34 ? 110 ARG U NH1 1 ATOM 1752 N NH2 . ARG B 2 110 ? 25.624 -23.096 19.004 1.00 57.72 ? 110 ARG U NH2 1 ATOM 1753 N N . GLU B 2 111 ? 23.295 -22.584 12.859 1.00 49.34 ? 111 GLU U N 1 ATOM 1754 C CA . GLU B 2 111 ? 22.861 -21.181 13.114 1.00 48.05 ? 111 GLU U CA 1 ATOM 1755 C C . GLU B 2 111 ? 21.359 -20.960 12.891 1.00 46.93 ? 111 GLU U C 1 ATOM 1756 O O . GLU B 2 111 ? 20.928 -20.792 11.756 1.00 46.87 ? 111 GLU U O 1 ATOM 1757 C CB . GLU B 2 111 ? 23.646 -20.197 12.207 1.00 48.33 ? 111 GLU U CB 1 ATOM 1758 C CG . GLU B 2 111 ? 23.497 -20.439 10.665 1.00 49.07 ? 111 GLU U CG 1 ATOM 1759 C CD . GLU B 2 111 ? 24.474 -19.637 9.780 1.00 50.19 ? 111 GLU U CD 1 ATOM 1760 O OE1 . GLU B 2 111 ? 24.868 -20.158 8.707 1.00 50.56 ? 111 GLU U OE1 1 ATOM 1761 O OE2 . GLU B 2 111 ? 24.844 -18.495 10.138 1.00 49.92 ? 111 GLU U OE2 1 ATOM 1762 N N . GLN B 2 112 ? 20.557 -20.929 13.949 1.00 45.76 ? 112 GLN U N 1 ATOM 1763 C CA . GLN B 2 112 ? 19.093 -20.774 13.771 1.00 44.94 ? 112 GLN U CA 1 ATOM 1764 C C . GLN B 2 112 ? 18.706 -19.667 12.756 1.00 43.86 ? 112 GLN U C 1 ATOM 1765 O O . GLN B 2 112 ? 19.305 -18.604 12.738 1.00 43.97 ? 112 GLN U O 1 ATOM 1766 C CB . GLN B 2 112 ? 18.358 -20.613 15.125 1.00 45.24 ? 112 GLN U CB 1 ATOM 1767 C CG . GLN B 2 112 ? 18.283 -21.932 15.963 1.00 46.54 ? 112 GLN U CG 1 ATOM 1768 C CD . GLN B 2 112 ? 17.132 -21.991 17.000 1.00 47.75 ? 112 GLN U CD 1 ATOM 1769 O OE1 . GLN B 2 112 ? 16.249 -22.856 16.916 1.00 47.48 ? 112 GLN U OE1 1 ATOM 1770 N NE2 . GLN B 2 112 ? 17.161 -21.090 17.985 1.00 47.76 ? 112 GLN U NE2 1 ATOM 1771 N N . SER B 2 113 ? 17.716 -19.933 11.905 1.00 42.52 ? 113 SER U N 1 ATOM 1772 C CA . SER B 2 113 ? 17.340 -19.017 10.826 1.00 40.89 ? 113 SER U CA 1 ATOM 1773 C C . SER B 2 113 ? 15.986 -18.348 11.023 1.00 39.88 ? 113 SER U C 1 ATOM 1774 O O . SER B 2 113 ? 15.268 -18.626 11.971 1.00 39.24 ? 113 SER U O 1 ATOM 1775 C CB . SER B 2 113 ? 17.344 -19.751 9.496 1.00 41.19 ? 113 SER U CB 1 ATOM 1776 O OG . SER B 2 113 ? 16.306 -20.714 9.457 1.00 41.59 ? 113 SER U OG 1 ATOM 1777 N N . LEU B 2 114 ? 15.642 -17.489 10.072 1.00 39.19 ? 114 LEU U N 1 ATOM 1778 C CA . LEU B 2 114 ? 14.621 -16.462 10.250 1.00 38.51 ? 114 LEU U CA 1 ATOM 1779 C C . LEU B 2 114 ? 14.103 -16.078 8.891 1.00 38.04 ? 114 LEU U C 1 ATOM 1780 O O . LEU B 2 114 ? 14.723 -16.383 7.871 1.00 37.88 ? 114 LEU U O 1 ATOM 1781 C CB . LEU B 2 114 ? 15.282 -15.220 10.845 1.00 38.64 ? 114 LEU U CB 1 ATOM 1782 C CG . LEU B 2 114 ? 14.624 -14.083 11.635 1.00 38.62 ? 114 LEU U CG 1 ATOM 1783 C CD1 . LEU B 2 114 ? 15.695 -13.077 11.943 1.00 38.40 ? 114 LEU U CD1 1 ATOM 1784 C CD2 . LEU B 2 114 ? 13.485 -13.377 10.932 1.00 39.14 ? 114 LEU U CD2 1 ATOM 1785 N N . GLN B 2 115 ? 12.995 -15.353 8.887 1.00 37.38 ? 115 GLN U N 1 ATOM 1786 C CA . GLN B 2 115 ? 12.316 -15.010 7.659 1.00 37.03 ? 115 GLN U CA 1 ATOM 1787 C C . GLN B 2 115 ? 11.803 -13.583 7.696 1.00 36.72 ? 115 GLN U C 1 ATOM 1788 O O . GLN B 2 115 ? 10.982 -13.240 8.542 1.00 36.81 ? 115 GLN U O 1 ATOM 1789 C CB . GLN B 2 115 ? 11.144 -15.953 7.503 1.00 37.05 ? 115 GLN U CB 1 ATOM 1790 C CG . GLN B 2 115 ? 10.751 -16.239 6.096 1.00 37.41 ? 115 GLN U CG 1 ATOM 1791 C CD . GLN B 2 115 ? 9.348 -16.752 6.038 1.00 37.71 ? 115 GLN U CD 1 ATOM 1792 O OE1 . GLN B 2 115 ? 8.652 -16.787 7.054 1.00 37.63 ? 115 GLN U OE1 1 ATOM 1793 N NE2 . GLN B 2 115 ? 8.906 -17.137 4.849 1.00 37.78 ? 115 GLN U NE2 1 ATOM 1794 N N . CYS B 2 116 ? 12.262 -12.759 6.766 1.00 36.57 ? 116 CYS U N 1 ATOM 1795 C CA . CYS B 2 116 ? 11.954 -11.332 6.790 1.00 37.03 ? 116 CYS U CA 1 ATOM 1796 C C . CYS B 2 116 ? 10.463 -11.070 6.874 1.00 37.56 ? 116 CYS U C 1 ATOM 1797 O O . CYS B 2 116 ? 9.684 -11.803 6.275 1.00 37.68 ? 116 CYS U O 1 ATOM 1798 C CB . CYS B 2 116 ? 12.488 -10.652 5.539 1.00 36.87 ? 116 CYS U CB 1 ATOM 1799 S SG . CYS B 2 116 ? 14.177 -11.060 4.979 1.00 36.84 ? 116 CYS U SG 1 ATOM 1800 N N . ARG B 2 117 ? 10.051 -10.028 7.596 1.00 38.32 ? 117 ARG U N 1 ATOM 1801 C CA . ARG B 2 117 ? 8.613 -9.719 7.644 1.00 39.16 ? 117 ARG U CA 1 ATOM 1802 C C . ARG B 2 117 ? 8.154 -8.480 6.840 1.00 39.43 ? 117 ARG U C 1 ATOM 1803 O O . ARG B 2 117 ? 7.020 -8.007 6.984 1.00 39.64 ? 117 ARG U O 1 ATOM 1804 C CB . ARG B 2 117 ? 8.055 -9.724 9.080 1.00 39.26 ? 117 ARG U CB 1 ATOM 1805 C CG . ARG B 2 117 ? 6.714 -10.496 9.199 1.00 39.73 ? 117 ARG U CG 1 ATOM 1806 C CD . ARG B 2 117 ? 6.112 -10.798 7.798 1.00 40.11 ? 117 ARG U CD 1 ATOM 1807 N NE . ARG B 2 117 ? 4.663 -10.629 7.710 1.00 40.78 ? 117 ARG U NE 1 ATOM 1808 C CZ . ARG B 2 117 ? 4.000 -9.496 7.960 1.00 41.57 ? 117 ARG U CZ 1 ATOM 1809 N NH1 . ARG B 2 117 ? 4.623 -8.386 8.354 1.00 41.62 ? 117 ARG U NH1 1 ATOM 1810 N NH2 . ARG B 2 117 ? 2.685 -9.479 7.836 1.00 42.28 ? 117 ARG U NH2 1 ATOM 1811 N N . TYR B 2 118 ? 9.031 -7.975 5.984 1.00 39.63 ? 118 TYR U N 1 ATOM 1812 C CA . TYR B 2 118 ? 8.639 -6.979 5.007 1.00 39.64 ? 118 TYR U CA 1 ATOM 1813 C C . TYR B 2 118 ? 9.122 -7.449 3.662 1.00 39.33 ? 118 TYR U C 1 ATOM 1814 O O . TYR B 2 118 ? 10.288 -7.840 3.534 1.00 39.57 ? 118 TYR U O 1 ATOM 1815 C CB . TYR B 2 118 ? 9.254 -5.605 5.312 1.00 39.80 ? 118 TYR U CB 1 ATOM 1816 C CG . TYR B 2 118 ? 8.813 -4.981 6.627 1.00 40.98 ? 118 TYR U CG 1 ATOM 1817 C CD1 . TYR B 2 118 ? 7.469 -5.027 7.036 1.00 41.84 ? 118 TYR U CD1 1 ATOM 1818 C CD2 . TYR B 2 118 ? 9.738 -4.326 7.455 1.00 41.49 ? 118 TYR U CD2 1 ATOM 1819 C CE1 . TYR B 2 118 ? 7.057 -4.457 8.243 1.00 43.01 ? 118 TYR U CE1 1 ATOM 1820 C CE2 . TYR B 2 118 ? 9.345 -3.746 8.662 1.00 42.55 ? 118 TYR U CE2 1 ATOM 1821 C CZ . TYR B 2 118 ? 7.997 -3.812 9.055 1.00 44.41 ? 118 TYR U CZ 1 ATOM 1822 O OH . TYR B 2 118 ? 7.588 -3.239 10.259 1.00 45.99 ? 118 TYR U OH 1 ATOM 1823 N N . PRO B 2 119 ? 8.222 -7.470 2.661 1.00 38.82 ? 119 PRO U N 1 ATOM 1824 C CA . PRO B 2 119 ? 8.734 -7.347 1.296 1.00 38.17 ? 119 PRO U CA 1 ATOM 1825 C C . PRO B 2 119 ? 9.551 -6.051 1.182 1.00 37.71 ? 119 PRO U C 1 ATOM 1826 O O . PRO B 2 119 ? 9.184 -5.047 1.812 1.00 37.74 ? 119 PRO U O 1 ATOM 1827 C CB . PRO B 2 119 ? 7.458 -7.297 0.466 1.00 38.15 ? 119 PRO U CB 1 ATOM 1828 C CG . PRO B 2 119 ? 6.493 -8.205 1.243 1.00 38.20 ? 119 PRO U CG 1 ATOM 1829 C CD . PRO B 2 119 ? 6.847 -8.020 2.700 1.00 38.80 ? 119 PRO U CD 1 ATOM 1830 N N . THR B 2 120 ? 10.643 -6.108 0.404 1.00 37.16 ? 120 THR U N 1 ATOM 1831 C CA . THR B 2 120 ? 11.734 -5.080 0.268 1.00 36.66 ? 120 THR U CA 1 ATOM 1832 C C . THR B 2 120 ? 12.946 -5.351 1.135 1.00 36.68 ? 120 THR U C 1 ATOM 1833 O O . THR B 2 120 ? 14.030 -4.817 0.868 1.00 36.62 ? 120 THR U O 1 ATOM 1834 C CB . THR B 2 120 ? 11.352 -3.583 0.484 1.00 36.67 ? 120 THR U CB 1 ATOM 1835 O OG1 . THR B 2 120 ? 10.895 -3.353 1.828 1.00 34.96 ? 120 THR U OG1 1 ATOM 1836 C CG2 . THR B 2 120 ? 10.339 -3.110 -0.570 1.00 37.18 ? 120 THR U CG2 1 ATOM 1837 N N . GLU B 2 121 ? 12.745 -6.162 2.179 1.00 36.64 ? 121 GLU U N 1 ATOM 1838 C CA . GLU B 2 121 ? 13.821 -6.645 3.048 1.00 36.45 ? 121 GLU U CA 1 ATOM 1839 C C . GLU B 2 121 ? 14.792 -7.487 2.255 1.00 35.78 ? 121 GLU U C 1 ATOM 1840 O O . GLU B 2 121 ? 14.521 -7.832 1.128 1.00 35.88 ? 121 GLU U O 1 ATOM 1841 C CB . GLU B 2 121 ? 13.242 -7.494 4.163 1.00 36.72 ? 121 GLU U CB 1 ATOM 1842 C CG . GLU B 2 121 ? 12.792 -6.723 5.385 1.00 39.28 ? 121 GLU U CG 1 ATOM 1843 C CD . GLU B 2 121 ? 13.481 -7.224 6.679 1.00 42.84 ? 121 GLU U CD 1 ATOM 1844 O OE1 . GLU B 2 121 ? 14.290 -8.177 6.580 1.00 42.89 ? 121 GLU U OE1 1 ATOM 1845 O OE2 . GLU B 2 121 ? 13.235 -6.662 7.788 1.00 43.63 ? 121 GLU U OE2 1 ATOM 1846 N N . HIS B 2 122 ? 15.926 -7.829 2.831 1.00 35.44 ? 122 HIS U N 1 ATOM 1847 C CA . HIS B 2 122 ? 16.872 -8.663 2.119 1.00 35.62 ? 122 HIS U CA 1 ATOM 1848 C C . HIS B 2 122 ? 17.400 -9.749 3.001 1.00 35.98 ? 122 HIS U C 1 ATOM 1849 O O . HIS B 2 122 ? 16.832 -10.029 4.041 1.00 36.37 ? 122 HIS U O 1 ATOM 1850 C CB . HIS B 2 122 ? 18.030 -7.827 1.634 1.00 35.33 ? 122 HIS U CB 1 ATOM 1851 C CG . HIS B 2 122 ? 17.707 -7.024 0.421 1.00 36.03 ? 122 HIS U CG 1 ATOM 1852 N ND1 . HIS B 2 122 ? 18.012 -7.454 -0.855 1.00 35.50 ? 122 HIS U ND1 1 ATOM 1853 C CD2 . HIS B 2 122 ? 17.099 -5.823 0.284 1.00 36.18 ? 122 HIS U CD2 1 ATOM 1854 C CE1 . HIS B 2 122 ? 17.613 -6.546 -1.726 1.00 35.44 ? 122 HIS U CE1 1 ATOM 1855 N NE2 . HIS B 2 122 ? 17.055 -5.548 -1.061 1.00 36.64 ? 122 HIS U NE2 1 ATOM 1856 N N . CYS B 2 123 ? 18.485 -10.377 2.579 1.00 36.34 ? 123 CYS U N 1 ATOM 1857 C CA . CYS B 2 123 ? 19.252 -11.224 3.470 1.00 36.78 ? 123 CYS U CA 1 ATOM 1858 C C . CYS B 2 123 ? 20.562 -10.509 3.639 1.00 36.69 ? 123 CYS U C 1 ATOM 1859 O O . CYS B 2 123 ? 21.063 -9.945 2.664 1.00 37.00 ? 123 CYS U O 1 ATOM 1860 C CB . CYS B 2 123 ? 19.500 -12.572 2.827 1.00 36.92 ? 123 CYS U CB 1 ATOM 1861 S SG . CYS B 2 123 ? 18.047 -13.628 2.649 1.00 39.49 ? 123 CYS U SG 1 ATOM 1862 N N . ILE B 2 124 ? 21.126 -10.511 4.849 1.00 36.43 ? 124 ILE U N 1 ATOM 1863 C CA . ILE B 2 124 ? 22.415 -9.832 5.055 1.00 36.15 ? 124 ILE U CA 1 ATOM 1864 C C . ILE B 2 124 ? 23.420 -10.478 5.995 1.00 36.03 ? 124 ILE U C 1 ATOM 1865 O O . ILE B 2 124 ? 23.060 -11.096 6.993 1.00 35.68 ? 124 ILE U O 1 ATOM 1866 C CB . ILE B 2 124 ? 22.267 -8.333 5.456 1.00 36.12 ? 124 ILE U CB 1 ATOM 1867 C CG1 . ILE B 2 124 ? 21.515 -8.170 6.784 1.00 36.41 ? 124 ILE U CG1 1 ATOM 1868 C CG2 . ILE B 2 124 ? 21.642 -7.530 4.324 1.00 35.90 ? 124 ILE U CG2 1 ATOM 1869 C CD1 . ILE B 2 124 ? 20.034 -7.792 6.659 1.00 35.19 ? 124 ILE U CD1 1 ATOM 1870 N N . GLU B 2 125 ? 24.688 -10.329 5.621 1.00 36.19 ? 125 GLU U N 1 ATOM 1871 C CA . GLU B 2 125 ? 25.826 -10.562 6.497 1.00 36.73 ? 125 GLU U CA 1 ATOM 1872 C C . GLU B 2 125 ? 26.551 -9.241 6.731 1.00 36.38 ? 125 GLU U C 1 ATOM 1873 O O . GLU B 2 125 ? 26.864 -8.518 5.783 1.00 36.43 ? 125 GLU U O 1 ATOM 1874 C CB . GLU B 2 125 ? 26.813 -11.560 5.880 1.00 37.05 ? 125 GLU U CB 1 ATOM 1875 C CG . GLU B 2 125 ? 26.698 -13.003 6.410 1.00 39.85 ? 125 GLU U CG 1 ATOM 1876 C CD . GLU B 2 125 ? 28.035 -13.796 6.423 1.00 43.32 ? 125 GLU U CD 1 ATOM 1877 O OE1 . GLU B 2 125 ? 28.460 -14.205 7.530 1.00 44.72 ? 125 GLU U OE1 1 ATOM 1878 O OE2 . GLU B 2 125 ? 28.656 -14.023 5.349 1.00 44.04 ? 125 GLU U OE2 1 ATOM 1879 N N . VAL B 2 126 ? 26.839 -8.931 7.987 1.00 36.04 ? 126 VAL U N 1 ATOM 1880 C CA . VAL B 2 126 ? 27.633 -7.753 8.300 1.00 35.65 ? 126 VAL U CA 1 ATOM 1881 C C . VAL B 2 126 ? 28.846 -8.097 9.164 1.00 36.25 ? 126 VAL U C 1 ATOM 1882 O O . VAL B 2 126 ? 28.718 -8.699 10.236 1.00 36.30 ? 126 VAL U O 1 ATOM 1883 C CB . VAL B 2 126 ? 26.748 -6.640 8.898 1.00 35.04 ? 126 VAL U CB 1 ATOM 1884 C CG1 . VAL B 2 126 ? 25.710 -7.229 9.766 1.00 34.69 ? 126 VAL U CG1 1 ATOM 1885 C CG2 . VAL B 2 126 ? 27.558 -5.603 9.629 1.00 33.85 ? 126 VAL U CG2 1 ATOM 1886 N N . VAL B 2 127 ? 30.026 -7.729 8.680 1.00 36.83 ? 127 VAL U N 1 ATOM 1887 C CA . VAL B 2 127 ? 31.238 -8.046 9.399 1.00 38.01 ? 127 VAL U CA 1 ATOM 1888 C C . VAL B 2 127 ? 31.978 -6.807 9.889 1.00 39.00 ? 127 VAL U C 1 ATOM 1889 O O . VAL B 2 127 ? 32.151 -5.860 9.134 1.00 39.20 ? 127 VAL U O 1 ATOM 1890 C CB . VAL B 2 127 ? 32.157 -8.945 8.557 1.00 38.04 ? 127 VAL U CB 1 ATOM 1891 C CG1 . VAL B 2 127 ? 32.453 -8.310 7.225 1.00 37.38 ? 127 VAL U CG1 1 ATOM 1892 C CG2 . VAL B 2 127 ? 33.449 -9.273 9.307 1.00 38.25 ? 127 VAL U CG2 1 ATOM 1893 N N . THR B 2 128 ? 32.384 -6.824 11.164 1.00 40.33 ? 128 THR U N 1 ATOM 1894 C CA . THR B 2 128 ? 33.237 -5.786 11.771 1.00 41.50 ? 128 THR U CA 1 ATOM 1895 C C . THR B 2 128 ? 34.395 -6.396 12.577 1.00 42.68 ? 128 THR U C 1 ATOM 1896 O O . THR B 2 128 ? 34.192 -6.915 13.687 1.00 43.07 ? 128 THR U O 1 ATOM 1897 C CB . THR B 2 128 ? 32.452 -4.843 12.707 1.00 41.11 ? 128 THR U CB 1 ATOM 1898 O OG1 . THR B 2 128 ? 31.440 -4.151 11.972 1.00 40.70 ? 128 THR U OG1 1 ATOM 1899 C CG2 . THR B 2 128 ? 33.388 -3.823 13.307 1.00 40.96 ? 128 THR U CG2 1 ATOM 1900 N N . LEU B 2 129 ? 35.604 -6.327 12.025 1.00 43.89 ? 129 LEU U N 1 ATOM 1901 C CA . LEU B 2 129 ? 36.777 -6.870 12.711 1.00 45.00 ? 129 LEU U CA 1 ATOM 1902 C C . LEU B 2 129 ? 37.734 -5.757 13.091 1.00 45.81 ? 129 LEU U C 1 ATOM 1903 O O . LEU B 2 129 ? 38.190 -4.995 12.223 1.00 45.94 ? 129 LEU U O 1 ATOM 1904 C CB . LEU B 2 129 ? 37.500 -7.920 11.860 1.00 45.04 ? 129 LEU U CB 1 ATOM 1905 C CG . LEU B 2 129 ? 36.762 -9.142 11.291 1.00 45.33 ? 129 LEU U CG 1 ATOM 1906 C CD1 . LEU B 2 129 ? 37.784 -10.202 10.885 1.00 45.41 ? 129 LEU U CD1 1 ATOM 1907 C CD2 . LEU B 2 129 ? 35.727 -9.740 12.259 1.00 45.50 ? 129 LEU U CD2 1 ATOM 1908 N N . GLN B 2 130 ? 38.033 -5.687 14.392 1.00 46.68 ? 130 GLN U N 1 ATOM 1909 C CA . GLN B 2 130 ? 38.838 -4.613 15.000 1.00 47.26 ? 130 GLN U CA 1 ATOM 1910 C C . GLN B 2 130 ? 39.920 -5.152 15.958 1.00 47.83 ? 130 GLN U C 1 ATOM 1911 O O . GLN B 2 130 ? 39.736 -6.195 16.597 1.00 48.28 ? 130 GLN U O 1 ATOM 1912 C CB . GLN B 2 130 ? 37.907 -3.645 15.719 1.00 46.79 ? 130 GLN U CB 1 ATOM 1913 C CG . GLN B 2 130 ? 36.643 -4.326 16.207 1.00 47.04 ? 130 GLN U CG 1 ATOM 1914 C CD . GLN B 2 130 ? 35.576 -3.359 16.699 1.00 48.66 ? 130 GLN U CD 1 ATOM 1915 O OE1 . GLN B 2 130 ? 35.748 -2.131 16.674 1.00 48.02 ? 130 GLN U OE1 1 ATOM 1916 N NE2 . GLN B 2 130 ? 34.457 -3.917 17.157 1.00 49.46 ? 130 GLN U NE2 1 ATOM 1917 N N . SER B 2 131 ? 41.045 -4.447 16.058 1.00 48.29 ? 131 SER U N 1 ATOM 1918 C CA . SER B 2 131 ? 42.143 -4.886 16.930 1.00 48.80 ? 131 SER U CA 1 ATOM 1919 C C . SER B 2 131 ? 42.234 -4.209 18.327 1.00 49.25 ? 131 SER U C 1 ATOM 1920 O O . SER B 2 131 ? 41.441 -3.311 18.660 1.00 49.49 ? 131 SER U O 1 ATOM 1921 C CB . SER B 2 131 ? 43.475 -4.817 16.182 1.00 48.59 ? 131 SER U CB 1 ATOM 1922 O OG . SER B 2 131 ? 43.635 -5.966 15.371 1.00 48.75 ? 131 SER U OG 1 ATOM 1923 N N . THR B 2 132 ? 43.194 -4.683 19.131 1.00 49.50 ? 132 THR U N 1 ATOM 1924 C CA . THR B 2 132 ? 43.486 -4.193 20.496 1.00 49.52 ? 132 THR U CA 1 ATOM 1925 C C . THR B 2 132 ? 42.237 -3.762 21.316 1.00 49.41 ? 132 THR U C 1 ATOM 1926 O O . THR B 2 132 ? 41.347 -4.592 21.530 1.00 49.51 ? 132 THR U O 1 ATOM 1927 C CB . THR B 2 132 ? 44.682 -3.173 20.502 1.00 49.79 ? 132 THR U CB 1 ATOM 1928 O OG1 . THR B 2 132 ? 44.953 -2.739 19.163 1.00 50.19 ? 132 THR U OG1 1 ATOM 1929 C CG2 . THR B 2 132 ? 45.966 -3.822 21.045 1.00 49.76 ? 132 THR U CG2 1 ATOM 1930 N N . GLU B 2 133 ? 42.157 -2.504 21.770 1.00 49.22 ? 133 GLU U N 1 ATOM 1931 C CA . GLU B 2 133 ? 41.018 -2.062 22.614 1.00 49.06 ? 133 GLU U CA 1 ATOM 1932 C C . GLU B 2 133 ? 39.916 -1.372 21.830 1.00 48.45 ? 133 GLU U C 1 ATOM 1933 O O . GLU B 2 133 ? 39.266 -0.467 22.361 1.00 48.48 ? 133 GLU U O 1 ATOM 1934 C CB . GLU B 2 133 ? 41.442 -1.142 23.771 1.00 49.27 ? 133 GLU U CB 1 ATOM 1935 C CG . GLU B 2 133 ? 42.268 -1.788 24.877 1.00 51.18 ? 133 GLU U CG 1 ATOM 1936 C CD . GLU B 2 133 ? 43.753 -1.498 24.722 1.00 54.04 ? 133 GLU U CD 1 ATOM 1937 O OE1 . GLU B 2 133 ? 44.091 -0.573 23.943 1.00 55.28 ? 133 GLU U OE1 1 ATOM 1938 O OE2 . GLU B 2 133 ? 44.581 -2.184 25.374 1.00 55.25 ? 133 GLU U OE2 1 ATOM 1939 N N . ARG B 2 134 ? 39.755 -1.785 20.570 1.00 47.67 ? 134 ARG U N 1 ATOM 1940 C CA . ARG B 2 134 ? 38.625 -1.448 19.674 1.00 46.83 ? 134 ARG U CA 1 ATOM 1941 C C . ARG B 2 134 ? 37.598 -0.354 20.035 1.00 46.03 ? 134 ARG U C 1 ATOM 1942 O O . ARG B 2 134 ? 36.850 -0.470 21.017 1.00 45.79 ? 134 ARG U O 1 ATOM 1943 C CB . ARG B 2 134 ? 37.863 -2.724 19.325 1.00 47.15 ? 134 ARG U CB 1 ATOM 1944 C CG . ARG B 2 134 ? 37.272 -3.494 20.498 1.00 47.70 ? 134 ARG U CG 1 ATOM 1945 C CD . ARG B 2 134 ? 36.564 -4.746 19.980 1.00 49.44 ? 134 ARG U CD 1 ATOM 1946 N NE . ARG B 2 134 ? 36.924 -5.941 20.747 1.00 50.84 ? 134 ARG U NE 1 ATOM 1947 C CZ . ARG B 2 134 ? 38.038 -6.661 20.584 1.00 50.81 ? 134 ARG U CZ 1 ATOM 1948 N NH1 . ARG B 2 134 ? 38.950 -6.328 19.668 1.00 50.16 ? 134 ARG U NH1 1 ATOM 1949 N NH2 . ARG B 2 134 ? 38.238 -7.726 21.354 1.00 50.72 ? 134 ARG U NH2 1 ATOM 1950 N N . SER B 2 135 ? 37.525 0.662 19.177 1.00 45.05 ? 135 SER U N 1 ATOM 1951 C CA . SER B 2 135 ? 36.623 1.812 19.357 1.00 44.13 ? 135 SER U CA 1 ATOM 1952 C C . SER B 2 135 ? 35.127 1.524 19.278 1.00 43.47 ? 135 SER U C 1 ATOM 1953 O O . SER B 2 135 ? 34.343 2.341 19.742 1.00 43.19 ? 135 SER U O 1 ATOM 1954 C CB . SER B 2 135 ? 36.955 2.916 18.353 1.00 44.07 ? 135 SER U CB 1 ATOM 1955 O OG . SER B 2 135 ? 38.272 3.394 18.548 1.00 44.44 ? 135 SER U OG 1 ATOM 1956 N N . LEU B 2 136 ? 34.741 0.385 18.693 1.00 42.94 ? 136 LEU U N 1 ATOM 1957 C CA . LEU B 2 136 ? 33.328 0.076 18.407 1.00 42.25 ? 136 LEU U CA 1 ATOM 1958 C C . LEU B 2 136 ? 32.781 -1.144 19.151 1.00 41.61 ? 136 LEU U C 1 ATOM 1959 O O . LEU B 2 136 ? 33.433 -2.183 19.238 1.00 41.47 ? 136 LEU U O 1 ATOM 1960 C CB . LEU B 2 136 ? 33.109 -0.153 16.902 1.00 42.60 ? 136 LEU U CB 1 ATOM 1961 C CG . LEU B 2 136 ? 33.783 0.639 15.769 1.00 42.86 ? 136 LEU U CG 1 ATOM 1962 C CD1 . LEU B 2 136 ? 33.187 0.227 14.418 1.00 42.31 ? 136 LEU U CD1 1 ATOM 1963 C CD2 . LEU B 2 136 ? 33.672 2.154 15.957 1.00 43.59 ? 136 LEU U CD2 1 ATOM 1964 N N . LYS B 2 137 ? 31.555 -1.025 19.640 1.00 40.90 ? 137 LYS U N 1 ATOM 1965 C CA . LYS B 2 137 ? 30.929 -2.104 20.392 1.00 40.28 ? 137 LYS U CA 1 ATOM 1966 C C . LYS B 2 137 ? 29.993 -2.945 19.526 1.00 39.25 ? 137 LYS U C 1 ATOM 1967 O O . LYS B 2 137 ? 28.867 -3.236 19.910 1.00 38.54 ? 137 LYS U O 1 ATOM 1968 C CB . LYS B 2 137 ? 30.206 -1.530 21.631 1.00 40.96 ? 137 LYS U CB 1 ATOM 1969 C CG . LYS B 2 137 ? 31.147 -1.104 22.806 1.00 42.02 ? 137 LYS U CG 1 ATOM 1970 C CD . LYS B 2 137 ? 31.869 -2.324 23.440 1.00 43.84 ? 137 LYS U CD 1 ATOM 1971 C CE . LYS B 2 137 ? 33.228 -1.951 24.056 1.00 44.63 ? 137 LYS U CE 1 ATOM 1972 N NZ . LYS B 2 137 ? 34.179 -1.266 23.103 1.00 44.71 ? 137 LYS U NZ 1 ATOM 1973 N N . ASP B 2 138 ? 30.494 -3.349 18.361 1.00 38.79 ? 138 ASP U N 1 ATOM 1974 C CA . ASP B 2 138 ? 29.705 -4.052 17.315 1.00 38.24 ? 138 ASP U CA 1 ATOM 1975 C C . ASP B 2 138 ? 30.114 -5.521 17.143 1.00 37.23 ? 138 ASP U C 1 ATOM 1976 O O . ASP B 2 138 ? 31.309 -5.830 17.062 1.00 37.37 ? 138 ASP U O 1 ATOM 1977 C CB . ASP B 2 138 ? 29.885 -3.347 15.958 1.00 38.60 ? 138 ASP U CB 1 ATOM 1978 C CG . ASP B 2 138 ? 28.780 -2.329 15.643 1.00 39.90 ? 138 ASP U CG 1 ATOM 1979 O OD1 . ASP B 2 138 ? 28.409 -2.230 14.448 1.00 41.57 ? 138 ASP U OD1 1 ATOM 1980 O OD2 . ASP B 2 138 ? 28.291 -1.620 16.557 1.00 41.08 ? 138 ASP U OD2 1 ATOM 1981 N N . GLU B 2 139 ? 29.134 -6.417 17.056 1.00 35.68 ? 139 GLU U N 1 ATOM 1982 C CA . GLU B 2 139 ? 29.416 -7.825 16.832 1.00 34.81 ? 139 GLU U CA 1 ATOM 1983 C C . GLU B 2 139 ? 30.415 -8.019 15.682 1.00 34.25 ? 139 GLU U C 1 ATOM 1984 O O . GLU B 2 139 ? 30.526 -7.185 14.783 1.00 34.79 ? 139 GLU U O 1 ATOM 1985 C CB . GLU B 2 139 ? 28.122 -8.569 16.552 1.00 34.54 ? 139 GLU U CB 1 ATOM 1986 C CG . GLU B 2 139 ? 27.307 -8.750 17.795 1.00 36.42 ? 139 GLU U CG 1 ATOM 1987 C CD . GLU B 2 139 ? 25.804 -8.591 17.574 1.00 39.69 ? 139 GLU U CD 1 ATOM 1988 O OE1 . GLU B 2 139 ? 25.227 -7.527 17.941 1.00 39.39 ? 139 GLU U OE1 1 ATOM 1989 O OE2 . GLU B 2 139 ? 25.190 -9.540 17.038 1.00 41.84 ? 139 GLU U OE2 1 ATOM 1990 N N . ASP B 2 140 ? 31.169 -9.103 15.706 1.00 33.12 ? 140 ASP U N 1 ATOM 1991 C CA . ASP B 2 140 ? 32.093 -9.334 14.632 1.00 31.79 ? 140 ASP U CA 1 ATOM 1992 C C . ASP B 2 140 ? 31.314 -9.795 13.433 1.00 30.93 ? 140 ASP U C 1 ATOM 1993 O O . ASP B 2 140 ? 31.418 -9.220 12.367 1.00 31.11 ? 140 ASP U O 1 ATOM 1994 C CB . ASP B 2 140 ? 33.160 -10.324 15.052 1.00 31.99 ? 140 ASP U CB 1 ATOM 1995 C CG . ASP B 2 140 ? 34.169 -9.707 16.002 1.00 32.78 ? 140 ASP U CG 1 ATOM 1996 O OD1 . ASP B 2 140 ? 33.768 -8.873 16.852 1.00 34.59 ? 140 ASP U OD1 1 ATOM 1997 O OD2 . ASP B 2 140 ? 35.366 -10.049 15.903 1.00 32.55 ? 140 ASP U OD2 1 ATOM 1998 N N . TYR B 2 141 ? 30.494 -10.809 13.613 1.00 29.77 ? 141 TYR U N 1 ATOM 1999 C CA . TYR B 2 141 ? 29.723 -11.307 12.511 1.00 28.90 ? 141 TYR U CA 1 ATOM 2000 C C . TYR B 2 141 ? 28.277 -11.263 12.911 1.00 28.66 ? 141 TYR U C 1 ATOM 2001 O O . TYR B 2 141 ? 27.936 -11.568 14.059 1.00 28.44 ? 141 TYR U O 1 ATOM 2002 C CB . TYR B 2 141 ? 30.135 -12.733 12.169 1.00 28.69 ? 141 TYR U CB 1 ATOM 2003 C CG . TYR B 2 141 ? 31.584 -12.902 11.733 1.00 28.92 ? 141 TYR U CG 1 ATOM 2004 C CD1 . TYR B 2 141 ? 32.441 -13.774 12.407 1.00 28.78 ? 141 TYR U CD1 1 ATOM 2005 C CD2 . TYR B 2 141 ? 32.097 -12.209 10.629 1.00 30.40 ? 141 TYR U CD2 1 ATOM 2006 C CE1 . TYR B 2 141 ? 33.776 -13.949 11.998 1.00 28.67 ? 141 TYR U CE1 1 ATOM 2007 C CE2 . TYR B 2 141 ? 33.435 -12.378 10.210 1.00 29.61 ? 141 TYR U CE2 1 ATOM 2008 C CZ . TYR B 2 141 ? 34.261 -13.246 10.902 1.00 29.04 ? 141 TYR U CZ 1 ATOM 2009 O OH . TYR B 2 141 ? 35.568 -13.408 10.499 1.00 28.66 ? 141 TYR U OH 1 ATOM 2010 N N . THR B 2 142 ? 27.436 -10.849 11.968 1.00 28.35 ? 142 THR U N 1 ATOM 2011 C CA . THR B 2 142 ? 25.992 -10.821 12.156 1.00 28.30 ? 142 THR U CA 1 ATOM 2012 C C . THR B 2 142 ? 25.323 -11.197 10.858 1.00 28.30 ? 142 THR U C 1 ATOM 2013 O O . THR B 2 142 ? 25.684 -10.679 9.810 1.00 28.63 ? 142 THR U O 1 ATOM 2014 C CB . THR B 2 142 ? 25.480 -9.428 12.595 1.00 28.27 ? 142 THR U CB 1 ATOM 2015 O OG1 . THR B 2 142 ? 25.749 -9.225 13.983 1.00 29.07 ? 142 THR U OG1 1 ATOM 2016 C CG2 . THR B 2 142 ? 23.979 -9.303 12.405 1.00 28.48 ? 142 THR U CG2 1 ATOM 2017 N N . ARG B 2 143 ? 24.347 -12.097 10.940 1.00 28.33 ? 143 ARG U N 1 ATOM 2018 C CA . ARG B 2 143 ? 23.540 -12.499 9.799 1.00 28.51 ? 143 ARG U CA 1 ATOM 2019 C C . ARG B 2 143 ? 22.081 -12.276 10.137 1.00 28.62 ? 143 ARG U C 1 ATOM 2020 O O . ARG B 2 143 ? 21.649 -12.687 11.197 1.00 28.80 ? 143 ARG U O 1 ATOM 2021 C CB . ARG B 2 143 ? 23.749 -13.977 9.510 1.00 28.59 ? 143 ARG U CB 1 ATOM 2022 C CG . ARG B 2 143 ? 25.103 -14.335 8.950 1.00 28.92 ? 143 ARG U CG 1 ATOM 2023 C CD . ARG B 2 143 ? 25.042 -15.705 8.328 1.00 28.92 ? 143 ARG U CD 1 ATOM 2024 N NE . ARG B 2 143 ? 26.200 -15.999 7.492 1.00 28.23 ? 143 ARG U NE 1 ATOM 2025 C CZ . ARG B 2 143 ? 27.247 -16.691 7.910 1.00 29.34 ? 143 ARG U CZ 1 ATOM 2026 N NH1 . ARG B 2 143 ? 27.271 -17.129 9.167 1.00 30.85 ? 143 ARG U NH1 1 ATOM 2027 N NH2 . ARG B 2 143 ? 28.268 -16.930 7.090 1.00 28.70 ? 143 ARG U NH2 1 ATOM 2028 N N . GLY B 2 144 ? 21.320 -11.644 9.245 1.00 28.77 ? 144 GLY U N 1 ATOM 2029 C CA . GLY B 2 144 ? 19.918 -11.344 9.521 1.00 28.99 ? 144 GLY U CA 1 ATOM 2030 C C . GLY B 2 144 ? 19.147 -10.879 8.312 1.00 29.62 ? 144 GLY U C 1 ATOM 2031 O O . GLY B 2 144 ? 19.640 -10.974 7.189 1.00 29.84 ? 144 GLY U O 1 ATOM 2032 N N . CYS B 2 145 ? 17.930 -10.392 8.541 1.00 30.27 ? 145 CYS U N 1 ATOM 2033 C CA . CYS B 2 145 ? 17.095 -9.830 7.486 1.00 31.47 ? 145 CYS U CA 1 ATOM 2034 C C . CYS B 2 145 ? 17.104 -8.315 7.537 1.00 31.37 ? 145 CYS U C 1 ATOM 2035 O O . CYS B 2 145 ? 17.155 -7.745 8.616 1.00 31.65 ? 145 CYS U O 1 ATOM 2036 C CB . CYS B 2 145 ? 15.659 -10.312 7.626 1.00 31.48 ? 145 CYS U CB 1 ATOM 2037 S SG . CYS B 2 145 ? 15.236 -11.761 6.595 1.00 36.78 ? 145 CYS U SG 1 ATOM 2038 N N . GLY B 2 146 ? 17.055 -7.666 6.374 1.00 31.58 ? 146 GLY U N 1 ATOM 2039 C CA . GLY B 2 146 ? 16.820 -6.217 6.303 1.00 31.97 ? 146 GLY U CA 1 ATOM 2040 C C . GLY B 2 146 ? 17.464 -5.425 5.178 1.00 32.10 ? 146 GLY U C 1 ATOM 2041 O O . GLY B 2 146 ? 18.187 -5.979 4.364 1.00 32.60 ? 146 GLY U O 1 ATOM 2042 N N . SER B 2 147 ? 17.211 -4.118 5.147 1.00 32.18 ? 147 SER U N 1 ATOM 2043 C CA . SER B 2 147 ? 17.746 -3.242 4.100 1.00 32.41 ? 147 SER U CA 1 ATOM 2044 C C . SER B 2 147 ? 18.694 -2.164 4.623 1.00 32.51 ? 147 SER U C 1 ATOM 2045 O O . SER B 2 147 ? 18.380 -1.462 5.570 1.00 32.35 ? 147 SER U O 1 ATOM 2046 C CB . SER B 2 147 ? 16.598 -2.574 3.333 1.00 32.70 ? 147 SER U CB 1 ATOM 2047 O OG . SER B 2 147 ? 15.969 -1.578 4.127 1.00 32.05 ? 147 SER U OG 1 ATOM 2048 N N . LEU B 2 148 ? 19.850 -2.024 3.986 1.00 32.91 ? 148 LEU U N 1 ATOM 2049 C CA . LEU B 2 148 ? 20.806 -0.990 4.355 1.00 33.21 ? 148 LEU U CA 1 ATOM 2050 C C . LEU B 2 148 ? 21.305 -0.259 3.112 1.00 33.86 ? 148 LEU U C 1 ATOM 2051 O O . LEU B 2 148 ? 20.947 -0.626 1.985 1.00 33.62 ? 148 LEU U O 1 ATOM 2052 C CB . LEU B 2 148 ? 21.984 -1.602 5.105 1.00 33.04 ? 148 LEU U CB 1 ATOM 2053 C CG . LEU B 2 148 ? 21.704 -2.671 6.161 1.00 32.90 ? 148 LEU U CG 1 ATOM 2054 C CD1 . LEU B 2 148 ? 22.991 -3.296 6.651 1.00 32.74 ? 148 LEU U CD1 1 ATOM 2055 C CD2 . LEU B 2 148 ? 20.920 -2.130 7.320 1.00 33.48 ? 148 LEU U CD2 1 ATOM 2056 N N . PRO B 2 149 ? 22.145 0.779 3.307 1.00 34.56 ? 149 PRO U N 1 ATOM 2057 C CA . PRO B 2 149 ? 22.602 1.564 2.165 1.00 34.97 ? 149 PRO U CA 1 ATOM 2058 C C . PRO B 2 149 ? 23.197 0.670 1.115 1.00 35.45 ? 149 PRO U C 1 ATOM 2059 O O . PRO B 2 149 ? 23.954 -0.252 1.432 1.00 35.33 ? 149 PRO U O 1 ATOM 2060 C CB . PRO B 2 149 ? 23.682 2.483 2.749 1.00 35.12 ? 149 PRO U CB 1 ATOM 2061 C CG . PRO B 2 149 ? 23.975 1.960 4.123 1.00 34.86 ? 149 PRO U CG 1 ATOM 2062 C CD . PRO B 2 149 ? 22.723 1.273 4.570 1.00 34.65 ? 149 PRO U CD 1 ATOM 2063 N N . GLY B 2 150 ? 22.812 0.944 -0.126 1.00 36.23 ? 150 GLY U N 1 ATOM 2064 C CA . GLY B 2 150 ? 23.270 0.205 -1.296 1.00 36.67 ? 150 GLY U CA 1 ATOM 2065 C C . GLY B 2 150 ? 23.093 -1.267 -1.066 1.00 36.93 ? 150 GLY U C 1 ATOM 2066 O O . GLY B 2 150 ? 24.075 -1.993 -0.903 1.00 36.48 ? 150 GLY U O 1 ATOM 2067 N N . CYS B 2 151 ? 21.843 -1.711 -1.035 1.00 37.81 ? 151 CYS U N 1 ATOM 2068 C CA . CYS B 2 151 ? 21.617 -3.085 -0.622 1.00 38.91 ? 151 CYS U CA 1 ATOM 2069 C C . CYS B 2 151 ? 21.945 -4.130 -1.702 1.00 38.83 ? 151 CYS U C 1 ATOM 2070 O O . CYS B 2 151 ? 23.117 -4.527 -1.806 1.00 39.14 ? 151 CYS U O 1 ATOM 2071 C CB . CYS B 2 151 ? 20.283 -3.305 0.112 1.00 39.20 ? 151 CYS U CB 1 ATOM 2072 S SG . CYS B 2 151 ? 20.554 -4.338 1.612 1.00 40.49 ? 151 CYS U SG 1 ATOM 2073 N N . PRO B 2 152 ? 20.960 -4.553 -2.521 1.00 38.49 ? 152 PRO U N 1 ATOM 2074 C CA . PRO B 2 152 ? 21.323 -5.716 -3.337 1.00 38.02 ? 152 PRO U CA 1 ATOM 2075 C C . PRO B 2 152 ? 22.741 -5.507 -3.836 1.00 37.63 ? 152 PRO U C 1 ATOM 2076 O O . PRO B 2 152 ? 23.004 -4.566 -4.585 1.00 37.56 ? 152 PRO U O 1 ATOM 2077 C CB . PRO B 2 152 ? 20.310 -5.691 -4.489 1.00 37.87 ? 152 PRO U CB 1 ATOM 2078 C CG . PRO B 2 152 ? 19.803 -4.298 -4.539 1.00 38.65 ? 152 PRO U CG 1 ATOM 2079 C CD . PRO B 2 152 ? 19.853 -3.781 -3.110 1.00 38.69 ? 152 PRO U CD 1 ATOM 2080 N N . GLY B 2 153 ? 23.656 -6.341 -3.358 1.00 37.41 ? 153 GLY U N 1 ATOM 2081 C CA . GLY B 2 153 ? 25.074 -6.161 -3.633 1.00 37.48 ? 153 GLY U CA 1 ATOM 2082 C C . GLY B 2 153 ? 25.877 -6.193 -2.352 1.00 37.47 ? 153 GLY U C 1 ATOM 2083 O O . GLY B 2 153 ? 25.529 -6.920 -1.428 1.00 37.49 ? 153 GLY U O 1 ATOM 2084 N N . THR B 2 154 ? 26.936 -5.381 -2.291 1.00 37.57 ? 154 THR U N 1 ATOM 2085 C CA . THR B 2 154 ? 27.990 -5.503 -1.262 1.00 37.19 ? 154 THR U CA 1 ATOM 2086 C C . THR B 2 154 ? 28.753 -4.204 -0.985 1.00 36.96 ? 154 THR U C 1 ATOM 2087 O O . THR B 2 154 ? 28.962 -3.402 -1.887 1.00 37.01 ? 154 THR U O 1 ATOM 2088 C CB . THR B 2 154 ? 29.069 -6.532 -1.709 1.00 37.21 ? 154 THR U CB 1 ATOM 2089 O OG1 . THR B 2 154 ? 29.293 -6.412 -3.127 1.00 36.75 ? 154 THR U OG1 1 ATOM 2090 C CG2 . THR B 2 154 ? 28.659 -7.966 -1.356 1.00 36.68 ? 154 THR U CG2 1 ATOM 2091 N N . ALA B 2 155 ? 29.202 -4.026 0.254 1.00 36.70 ? 155 ALA U N 1 ATOM 2092 C CA . ALA B 2 155 ? 30.172 -2.973 0.584 1.00 36.47 ? 155 ALA U CA 1 ATOM 2093 C C . ALA B 2 155 ? 31.272 -3.474 1.525 1.00 36.27 ? 155 ALA U C 1 ATOM 2094 O O . ALA B 2 155 ? 31.102 -4.489 2.208 1.00 36.49 ? 155 ALA U O 1 ATOM 2095 C CB . ALA B 2 155 ? 29.468 -1.776 1.183 1.00 36.53 ? 155 ALA U CB 1 ATOM 2096 N N . GLY B 2 156 ? 32.392 -2.761 1.576 1.00 35.87 ? 156 GLY U N 1 ATOM 2097 C CA . GLY B 2 156 ? 33.504 -3.195 2.403 1.00 35.66 ? 156 GLY U CA 1 ATOM 2098 C C . GLY B 2 156 ? 34.787 -2.418 2.243 1.00 35.69 ? 156 GLY U C 1 ATOM 2099 O O . GLY B 2 156 ? 35.043 -1.773 1.225 1.00 35.63 ? 156 GLY U O 1 ATOM 2100 N N . PHE B 2 157 ? 35.606 -2.499 3.273 1.00 35.88 ? 157 PHE U N 1 ATOM 2101 C CA . PHE B 2 157 ? 36.842 -1.777 3.324 1.00 36.25 ? 157 PHE U CA 1 ATOM 2102 C C . PHE B 2 157 ? 37.694 -2.391 4.396 1.00 36.39 ? 157 PHE U C 1 ATOM 2103 O O . PHE B 2 157 ? 37.215 -2.678 5.493 1.00 36.24 ? 157 PHE U O 1 ATOM 2104 C CB . PHE B 2 157 ? 36.578 -0.319 3.678 1.00 36.52 ? 157 PHE U CB 1 ATOM 2105 C CG . PHE B 2 157 ? 37.667 0.315 4.504 1.00 37.49 ? 157 PHE U CG 1 ATOM 2106 C CD1 . PHE B 2 157 ? 38.936 0.569 3.953 1.00 37.57 ? 157 PHE U CD1 1 ATOM 2107 C CD2 . PHE B 2 157 ? 37.427 0.663 5.831 1.00 37.33 ? 157 PHE U CD2 1 ATOM 2108 C CE1 . PHE B 2 157 ? 39.944 1.146 4.710 1.00 37.18 ? 157 PHE U CE1 1 ATOM 2109 C CE2 . PHE B 2 157 ? 38.437 1.245 6.598 1.00 37.69 ? 157 PHE U CE2 1 ATOM 2110 C CZ . PHE B 2 157 ? 39.696 1.488 6.035 1.00 37.48 ? 157 PHE U CZ 1 ATOM 2111 N N . HIS B 2 158 ? 38.969 -2.563 4.090 1.00 36.77 ? 158 HIS U N 1 ATOM 2112 C CA . HIS B 2 158 ? 39.880 -3.061 5.081 1.00 37.40 ? 158 HIS U CA 1 ATOM 2113 C C . HIS B 2 158 ? 41.056 -2.135 5.302 1.00 38.07 ? 158 HIS U C 1 ATOM 2114 O O . HIS B 2 158 ? 41.474 -1.407 4.401 1.00 37.98 ? 158 HIS U O 1 ATOM 2115 C CB . HIS B 2 158 ? 40.350 -4.470 4.728 1.00 37.43 ? 158 HIS U CB 1 ATOM 2116 C CG . HIS B 2 158 ? 41.509 -4.511 3.783 1.00 36.93 ? 158 HIS U CG 1 ATOM 2117 N ND1 . HIS B 2 158 ? 41.359 -4.410 2.418 1.00 36.54 ? 158 HIS U ND1 1 ATOM 2118 C CD2 . HIS B 2 158 ? 42.835 -4.665 4.008 1.00 36.18 ? 158 HIS U CD2 1 ATOM 2119 C CE1 . HIS B 2 158 ? 42.545 -4.491 1.843 1.00 36.81 ? 158 HIS U CE1 1 ATOM 2120 N NE2 . HIS B 2 158 ? 43.456 -4.650 2.785 1.00 36.60 ? 158 HIS U NE2 1 ATOM 2121 N N . SER B 2 159 ? 41.558 -2.179 6.533 1.00 38.98 ? 159 SER U N 1 ATOM 2122 C CA . SER B 2 159 ? 42.721 -1.441 6.978 1.00 39.66 ? 159 SER U CA 1 ATOM 2123 C C . SER B 2 159 ? 43.685 -2.434 7.602 1.00 40.23 ? 159 SER U C 1 ATOM 2124 O O . SER B 2 159 ? 43.349 -3.611 7.757 1.00 40.05 ? 159 SER U O 1 ATOM 2125 C CB . SER B 2 159 ? 42.298 -0.413 8.019 1.00 39.47 ? 159 SER U CB 1 ATOM 2126 O OG . SER B 2 159 ? 43.431 0.169 8.624 1.00 39.97 ? 159 SER U OG 1 ATOM 2127 N N . ASN B 2 160 ? 44.878 -1.959 7.960 1.00 41.17 ? 160 ASN U N 1 ATOM 2128 C CA . ASN B 2 160 ? 45.844 -2.777 8.678 1.00 42.29 ? 160 ASN U CA 1 ATOM 2129 C C . ASN B 2 160 ? 45.206 -3.408 9.916 1.00 41.57 ? 160 ASN U C 1 ATOM 2130 O O . ASN B 2 160 ? 45.376 -4.599 10.149 1.00 41.72 ? 160 ASN U O 1 ATOM 2131 C CB . ASN B 2 160 ? 47.091 -1.961 9.039 1.00 43.26 ? 160 ASN U CB 1 ATOM 2132 C CG . ASN B 2 160 ? 48.013 -2.682 10.012 1.00 48.93 ? 160 ASN U CG 1 ATOM 2133 O OD1 . ASN B 2 160 ? 49.137 -3.057 9.668 1.00 49.60 ? 160 ASN U OD1 1 ATOM 2134 N ND2 . ASN B 2 160 ? 47.532 -2.876 11.240 1.00 59.15 ? 160 ASN U ND2 1 ATOM 2135 N N . GLN B 2 161 ? 44.453 -2.620 10.686 1.00 40.93 ? 161 GLN U N 1 ATOM 2136 C CA . GLN B 2 161 ? 43.873 -3.089 11.958 1.00 39.94 ? 161 GLN U CA 1 ATOM 2137 C C . GLN B 2 161 ? 42.363 -3.247 11.916 1.00 39.07 ? 161 GLN U C 1 ATOM 2138 O O . GLN B 2 161 ? 41.740 -3.526 12.940 1.00 39.12 ? 161 GLN U O 1 ATOM 2139 C CB . GLN B 2 161 ? 44.211 -2.156 13.139 1.00 40.07 ? 161 GLN U CB 1 ATOM 2140 C CG . GLN B 2 161 ? 45.398 -1.221 12.964 1.00 40.44 ? 161 GLN U CG 1 ATOM 2141 C CD . GLN B 2 161 ? 45.017 0.090 12.295 1.00 40.56 ? 161 GLN U CD 1 ATOM 2142 O OE1 . GLN B 2 161 ? 43.858 0.518 12.358 1.00 39.37 ? 161 GLN U OE1 1 ATOM 2143 N NE2 . GLN B 2 161 ? 45.998 0.737 11.648 1.00 40.41 ? 161 GLN U NE2 1 ATOM 2144 N N . THR B 2 162 ? 41.761 -3.060 10.752 1.00 37.97 ? 162 THR U N 1 ATOM 2145 C CA . THR B 2 162 ? 40.308 -3.035 10.705 1.00 36.87 ? 162 THR U CA 1 ATOM 2146 C C . THR B 2 162 ? 39.735 -3.595 9.418 1.00 36.14 ? 162 THR U C 1 ATOM 2147 O O . THR B 2 162 ? 40.318 -3.451 8.350 1.00 36.26 ? 162 THR U O 1 ATOM 2148 C CB . THR B 2 162 ? 39.793 -1.619 10.905 1.00 36.86 ? 162 THR U CB 1 ATOM 2149 O OG1 . THR B 2 162 ? 40.801 -0.849 11.572 1.00 36.59 ? 162 THR U OG1 1 ATOM 2150 C CG2 . THR B 2 162 ? 38.525 -1.643 11.735 1.00 36.70 ? 162 THR U CG2 1 ATOM 2151 N N . PHE B 2 163 ? 38.586 -4.242 9.529 1.00 34.97 ? 163 PHE U N 1 ATOM 2152 C CA . PHE B 2 163 ? 37.919 -4.762 8.355 1.00 33.94 ? 163 PHE U CA 1 ATOM 2153 C C . PHE B 2 163 ? 36.397 -4.785 8.495 1.00 32.98 ? 163 PHE U C 1 ATOM 2154 O O . PHE B 2 163 ? 35.832 -5.480 9.350 1.00 32.79 ? 163 PHE U O 1 ATOM 2155 C CB . PHE B 2 163 ? 38.462 -6.139 8.003 1.00 34.13 ? 163 PHE U CB 1 ATOM 2156 C CG . PHE B 2 163 ? 37.612 -6.893 7.017 1.00 35.43 ? 163 PHE U CG 1 ATOM 2157 C CD1 . PHE B 2 163 ? 37.409 -6.405 5.726 1.00 35.89 ? 163 PHE U CD1 1 ATOM 2158 C CD2 . PHE B 2 163 ? 37.021 -8.107 7.374 1.00 36.55 ? 163 PHE U CD2 1 ATOM 2159 C CE1 . PHE B 2 163 ? 36.619 -7.100 4.811 1.00 35.34 ? 163 PHE U CE1 1 ATOM 2160 C CE2 . PHE B 2 163 ? 36.237 -8.815 6.458 1.00 36.44 ? 163 PHE U CE2 1 ATOM 2161 C CZ . PHE B 2 163 ? 36.038 -8.301 5.176 1.00 35.96 ? 163 PHE U CZ 1 ATOM 2162 N N . HIS B 2 164 ? 35.746 -4.018 7.632 1.00 31.68 ? 164 HIS U N 1 ATOM 2163 C CA . HIS B 2 164 ? 34.311 -3.998 7.585 1.00 30.59 ? 164 HIS U CA 1 ATOM 2164 C C . HIS B 2 164 ? 33.865 -4.569 6.274 1.00 29.63 ? 164 HIS U C 1 ATOM 2165 O O . HIS B 2 164 ? 34.593 -4.544 5.299 1.00 29.28 ? 164 HIS U O 1 ATOM 2166 C CB . HIS B 2 164 ? 33.775 -2.583 7.716 1.00 30.81 ? 164 HIS U CB 1 ATOM 2167 C CG . HIS B 2 164 ? 34.234 -1.874 8.946 1.00 31.28 ? 164 HIS U CG 1 ATOM 2168 N ND1 . HIS B 2 164 ? 35.268 -0.964 8.936 1.00 32.39 ? 164 HIS U ND1 1 ATOM 2169 C CD2 . HIS B 2 164 ? 33.799 -1.935 10.223 1.00 32.53 ? 164 HIS U CD2 1 ATOM 2170 C CE1 . HIS B 2 164 ? 35.452 -0.491 10.154 1.00 32.67 ? 164 HIS U CE1 1 ATOM 2171 N NE2 . HIS B 2 164 ? 34.575 -1.068 10.955 1.00 33.78 ? 164 HIS U NE2 1 ATOM 2172 N N . PHE B 2 165 ? 32.642 -5.071 6.265 1.00 28.82 ? 165 PHE U N 1 ATOM 2173 C CA . PHE B 2 165 ? 32.057 -5.606 5.079 1.00 27.95 ? 165 PHE U CA 1 ATOM 2174 C C . PHE B 2 165 ? 30.591 -5.917 5.310 1.00 27.80 ? 165 PHE U C 1 ATOM 2175 O O . PHE B 2 165 ? 30.207 -6.484 6.333 1.00 27.48 ? 165 PHE U O 1 ATOM 2176 C CB . PHE B 2 165 ? 32.811 -6.855 4.683 1.00 27.72 ? 165 PHE U CB 1 ATOM 2177 C CG . PHE B 2 165 ? 32.392 -7.418 3.384 1.00 26.98 ? 165 PHE U CG 1 ATOM 2178 C CD1 . PHE B 2 165 ? 31.369 -8.352 3.323 1.00 26.22 ? 165 PHE U CD1 1 ATOM 2179 C CD2 . PHE B 2 165 ? 33.035 -7.039 2.223 1.00 26.64 ? 165 PHE U CD2 1 ATOM 2180 C CE1 . PHE B 2 165 ? 30.980 -8.887 2.132 1.00 26.76 ? 165 PHE U CE1 1 ATOM 2181 C CE2 . PHE B 2 165 ? 32.659 -7.572 1.015 1.00 26.89 ? 165 PHE U CE2 1 ATOM 2182 C CZ . PHE B 2 165 ? 31.625 -8.499 0.962 1.00 27.23 ? 165 PHE U CZ 1 ATOM 2183 N N . LEU B 2 166 ? 29.787 -5.538 4.331 1.00 27.81 ? 166 LEU U N 1 ATOM 2184 C CA . LEU B 2 166 ? 28.378 -5.838 4.295 1.00 28.18 ? 166 LEU U CA 1 ATOM 2185 C C . LEU B 2 166 ? 28.161 -6.713 3.070 1.00 29.33 ? 166 LEU U C 1 ATOM 2186 O O . LEU B 2 166 ? 28.904 -6.628 2.109 1.00 29.35 ? 166 LEU U O 1 ATOM 2187 C CB . LEU B 2 166 ? 27.598 -4.536 4.117 1.00 27.68 ? 166 LEU U CB 1 ATOM 2188 C CG . LEU B 2 166 ? 26.166 -4.296 4.603 1.00 25.43 ? 166 LEU U CG 1 ATOM 2189 C CD1 . LEU B 2 166 ? 25.550 -3.098 3.879 1.00 21.72 ? 166 LEU U CD1 1 ATOM 2190 C CD2 . LEU B 2 166 ? 25.300 -5.519 4.428 1.00 24.54 ? 166 LEU U CD2 1 ATOM 2191 N N . LYS B 2 167 ? 27.146 -7.560 3.114 1.00 30.84 ? 167 LYS U N 1 ATOM 2192 C CA . LYS B 2 167 ? 26.673 -8.295 1.942 1.00 32.43 ? 167 LYS U CA 1 ATOM 2193 C C . LYS B 2 167 ? 25.153 -8.409 2.047 1.00 33.90 ? 167 LYS U C 1 ATOM 2194 O O . LYS B 2 167 ? 24.609 -8.718 3.110 1.00 34.36 ? 167 LYS U O 1 ATOM 2195 C CB . LYS B 2 167 ? 27.325 -9.683 1.850 1.00 32.20 ? 167 LYS U CB 1 ATOM 2196 C CG . LYS B 2 167 ? 26.523 -10.723 1.058 1.00 31.74 ? 167 LYS U CG 1 ATOM 2197 C CD . LYS B 2 167 ? 27.339 -11.990 0.753 1.00 32.12 ? 167 LYS U CD 1 ATOM 2198 C CE . LYS B 2 167 ? 26.441 -13.236 0.532 1.00 32.01 ? 167 LYS U CE 1 ATOM 2199 N NZ . LYS B 2 167 ? 27.118 -14.374 -0.171 1.00 30.74 ? 167 LYS U NZ 1 ATOM 2200 N N . CYS B 2 168 ? 24.468 -8.164 0.940 1.00 35.39 ? 168 CYS U N 1 ATOM 2201 C CA . CYS B 2 168 ? 23.020 -8.054 0.958 1.00 36.73 ? 168 CYS U CA 1 ATOM 2202 C C . CYS B 2 168 ? 22.417 -8.695 -0.304 1.00 36.84 ? 168 CYS U C 1 ATOM 2203 O O . CYS B 2 168 ? 22.734 -8.272 -1.414 1.00 36.72 ? 168 CYS U O 1 ATOM 2204 C CB . CYS B 2 168 ? 22.638 -6.566 1.119 1.00 36.71 ? 168 CYS U CB 1 ATOM 2205 S SG . CYS B 2 168 ? 20.893 -6.205 0.827 1.00 40.09 ? 168 CYS U SG 1 ATOM 2206 N N . CYS B 2 169 ? 21.571 -9.716 -0.135 1.00 37.61 ? 169 CYS U N 1 ATOM 2207 C CA . CYS B 2 169 ? 20.940 -10.398 -1.297 1.00 38.69 ? 169 CYS U CA 1 ATOM 2208 C C . CYS B 2 169 ? 19.452 -10.810 -1.210 1.00 39.00 ? 169 CYS U C 1 ATOM 2209 O O . CYS B 2 169 ? 18.937 -11.148 -0.132 1.00 39.05 ? 169 CYS U O 1 ATOM 2210 C CB . CYS B 2 169 ? 21.792 -11.571 -1.799 1.00 38.71 ? 169 CYS U CB 1 ATOM 2211 S SG . CYS B 2 169 ? 22.596 -12.525 -0.524 1.00 40.02 ? 169 CYS U SG 1 ATOM 2212 N N . ASN B 2 170 ? 18.797 -10.806 -2.379 1.00 39.28 ? 170 ASN U N 1 ATOM 2213 C CA . ASN B 2 170 ? 17.367 -11.079 -2.506 1.00 39.69 ? 170 ASN U CA 1 ATOM 2214 C C . ASN B 2 170 ? 17.082 -12.548 -2.842 1.00 38.75 ? 170 ASN U C 1 ATOM 2215 O O . ASN B 2 170 ? 16.203 -12.847 -3.646 1.00 38.82 ? 170 ASN U O 1 ATOM 2216 C CB . ASN B 2 170 ? 16.744 -10.106 -3.532 1.00 40.34 ? 170 ASN U CB 1 ATOM 2217 C CG . ASN B 2 170 ? 15.275 -10.424 -3.875 1.00 44.29 ? 170 ASN U CG 1 ATOM 2218 O OD1 . ASN B 2 170 ? 14.574 -11.160 -3.158 1.00 44.32 ? 170 ASN U OD1 1 ATOM 2219 N ND2 . ASN B 2 170 ? 14.811 -9.835 -4.988 1.00 50.76 ? 170 ASN U ND2 1 ATOM 2220 N N . TYR B 2 171 ? 17.811 -13.473 -2.220 1.00 37.76 ? 171 TYR U N 1 ATOM 2221 C CA . TYR B 2 171 ? 17.564 -14.889 -2.489 1.00 36.69 ? 171 TYR U CA 1 ATOM 2222 C C . TYR B 2 171 ? 17.678 -15.833 -1.303 1.00 36.59 ? 171 TYR U C 1 ATOM 2223 O O . TYR B 2 171 ? 18.504 -15.654 -0.421 1.00 36.73 ? 171 TYR U O 1 ATOM 2224 C CB . TYR B 2 171 ? 18.363 -15.366 -3.701 1.00 36.42 ? 171 TYR U CB 1 ATOM 2225 C CG . TYR B 2 171 ? 19.732 -15.972 -3.488 1.00 34.92 ? 171 TYR U CG 1 ATOM 2226 C CD1 . TYR B 2 171 ? 20.874 -15.333 -3.984 1.00 33.76 ? 171 TYR U CD1 1 ATOM 2227 C CD2 . TYR B 2 171 ? 19.880 -17.229 -2.885 1.00 33.43 ? 171 TYR U CD2 1 ATOM 2228 C CE1 . TYR B 2 171 ? 22.133 -15.901 -3.843 1.00 33.22 ? 171 TYR U CE1 1 ATOM 2229 C CE2 . TYR B 2 171 ? 21.131 -17.809 -2.738 1.00 33.06 ? 171 TYR U CE2 1 ATOM 2230 C CZ . TYR B 2 171 ? 22.253 -17.138 -3.218 1.00 33.46 ? 171 TYR U CZ 1 ATOM 2231 O OH . TYR B 2 171 ? 23.493 -17.706 -3.074 1.00 34.01 ? 171 TYR U OH 1 ATOM 2232 N N . THR B 2 172 ? 16.827 -16.846 -1.302 1.00 36.33 ? 172 THR U N 1 ATOM 2233 C CA . THR B 2 172 ? 16.662 -17.722 -0.153 1.00 36.38 ? 172 THR U CA 1 ATOM 2234 C C . THR B 2 172 ? 17.981 -18.258 0.414 1.00 36.41 ? 172 THR U C 1 ATOM 2235 O O . THR B 2 172 ? 18.824 -18.785 -0.325 1.00 36.50 ? 172 THR U O 1 ATOM 2236 C CB . THR B 2 172 ? 15.678 -18.854 -0.471 1.00 36.35 ? 172 THR U CB 1 ATOM 2237 O OG1 . THR B 2 172 ? 14.466 -18.276 -0.964 1.00 36.27 ? 172 THR U OG1 1 ATOM 2238 C CG2 . THR B 2 172 ? 15.365 -19.683 0.779 1.00 36.69 ? 172 THR U CG2 1 ATOM 2239 N N . HIS B 2 173 ? 18.126 -18.091 1.734 1.00 36.18 ? 173 HIS U N 1 ATOM 2240 C CA . HIS B 2 173 ? 19.317 -18.442 2.500 1.00 36.02 ? 173 HIS U CA 1 ATOM 2241 C C . HIS B 2 173 ? 20.607 -18.004 1.870 1.00 36.13 ? 173 HIS U C 1 ATOM 2242 O O . HIS B 2 173 ? 21.632 -18.630 2.111 1.00 36.13 ? 173 HIS U O 1 ATOM 2243 C CB . HIS B 2 173 ? 19.392 -19.941 2.775 1.00 35.82 ? 173 HIS U CB 1 ATOM 2244 C CG . HIS B 2 173 ? 19.029 -20.306 4.174 1.00 36.39 ? 173 HIS U CG 1 ATOM 2245 N ND1 . HIS B 2 173 ? 18.031 -21.208 4.476 1.00 36.85 ? 173 HIS U ND1 1 ATOM 2246 C CD2 . HIS B 2 173 ? 19.513 -19.870 5.359 1.00 36.97 ? 173 HIS U CD2 1 ATOM 2247 C CE1 . HIS B 2 173 ? 17.918 -21.316 5.786 1.00 36.78 ? 173 HIS U CE1 1 ATOM 2248 N NE2 . HIS B 2 173 ? 18.806 -20.513 6.346 1.00 37.35 ? 173 HIS U NE2 1 ATOM 2249 N N . CYS B 2 174 ? 20.568 -16.923 1.095 1.00 36.44 ? 174 CYS U N 1 ATOM 2250 C CA . CYS B 2 174 ? 21.719 -16.525 0.278 1.00 37.25 ? 174 CYS U CA 1 ATOM 2251 C C . CYS B 2 174 ? 23.007 -16.276 1.045 1.00 37.33 ? 174 CYS U C 1 ATOM 2252 O O . CYS B 2 174 ? 24.051 -16.023 0.426 1.00 37.38 ? 174 CYS U O 1 ATOM 2253 C CB . CYS B 2 174 ? 21.403 -15.313 -0.602 1.00 37.53 ? 174 CYS U CB 1 ATOM 2254 S SG . CYS B 2 174 ? 21.120 -13.722 0.202 1.00 39.77 ? 174 CYS U SG 1 ATOM 2255 N N . ASN B 2 175 ? 22.922 -16.370 2.377 1.00 37.42 ? 175 ASN U N 1 ATOM 2256 C CA . ASN B 2 175 ? 24.011 -16.026 3.293 1.00 37.23 ? 175 ASN U CA 1 ATOM 2257 C C . ASN B 2 175 ? 24.392 -17.114 4.320 1.00 37.45 ? 175 ASN U C 1 ATOM 2258 O O . ASN B 2 175 ? 24.840 -16.810 5.418 1.00 37.75 ? 175 ASN U O 1 ATOM 2259 C CB . ASN B 2 175 ? 23.646 -14.736 4.021 1.00 36.73 ? 175 ASN U CB 1 ATOM 2260 C CG . ASN B 2 175 ? 22.357 -14.858 4.821 1.00 36.39 ? 175 ASN U CG 1 ATOM 2261 O OD1 . ASN B 2 175 ? 21.439 -14.086 4.613 1.00 36.53 ? 175 ASN U OD1 1 ATOM 2262 N ND2 . ASN B 2 175 ? 22.285 -15.826 5.738 1.00 35.55 ? 175 ASN U ND2 1 ATOM 2263 N N . GLY B 2 176 ? 24.212 -18.380 3.986 1.00 37.66 ? 176 GLY U N 1 ATOM 2264 C CA . GLY B 2 176 ? 24.604 -19.432 4.917 1.00 38.04 ? 176 GLY U CA 1 ATOM 2265 C C . GLY B 2 176 ? 26.090 -19.693 4.787 1.00 38.31 ? 176 GLY U C 1 ATOM 2266 O O . GLY B 2 176 ? 26.876 -18.760 4.597 1.00 38.08 ? 176 GLY U O 1 ATOM 2267 N N . GLY B 2 177 ? 26.463 -20.971 4.881 1.00 38.60 ? 177 GLY U N 1 ATOM 2268 C CA . GLY B 2 177 ? 27.842 -21.436 4.663 1.00 38.80 ? 177 GLY U CA 1 ATOM 2269 C C . GLY B 2 177 ? 28.976 -20.693 5.366 1.00 38.85 ? 177 GLY U C 1 ATOM 2270 O O . GLY B 2 177 ? 28.745 -20.000 6.361 1.00 38.80 ? 177 GLY U O 1 ATOM 2271 N N . PRO B 2 178 ? 30.214 -20.833 4.843 1.00 38.99 ? 178 PRO U N 1 ATOM 2272 C CA . PRO B 2 178 ? 31.412 -20.222 5.408 1.00 39.09 ? 178 PRO U CA 1 ATOM 2273 C C . PRO B 2 178 ? 31.159 -18.802 5.848 1.00 39.26 ? 178 PRO U C 1 ATOM 2274 O O . PRO B 2 178 ? 30.366 -18.091 5.237 1.00 39.48 ? 178 PRO U O 1 ATOM 2275 C CB . PRO B 2 178 ? 32.383 -20.197 4.228 1.00 39.08 ? 178 PRO U CB 1 ATOM 2276 C CG . PRO B 2 178 ? 31.998 -21.370 3.396 1.00 39.39 ? 178 PRO U CG 1 ATOM 2277 C CD . PRO B 2 178 ? 30.524 -21.620 3.631 1.00 39.24 ? 178 PRO U CD 1 ATOM 2278 N N . VAL B 2 179 ? 31.830 -18.391 6.910 1.00 39.36 ? 179 VAL U N 1 ATOM 2279 C CA . VAL B 2 179 ? 31.813 -16.998 7.308 1.00 39.25 ? 179 VAL U CA 1 ATOM 2280 C C . VAL B 2 179 ? 32.843 -16.274 6.411 1.00 39.37 ? 179 VAL U C 1 ATOM 2281 O O . VAL B 2 179 ? 33.236 -16.819 5.371 1.00 39.44 ? 179 VAL U O 1 ATOM 2282 C CB . VAL B 2 179 ? 32.127 -16.861 8.805 1.00 39.26 ? 179 VAL U CB 1 ATOM 2283 C CG1 . VAL B 2 179 ? 31.386 -15.680 9.372 1.00 38.74 ? 179 VAL U CG1 1 ATOM 2284 C CG2 . VAL B 2 179 ? 31.751 -18.152 9.558 1.00 38.88 ? 179 VAL U CG2 1 ATOM 2285 N N . LEU B 2 180 ? 33.281 -15.068 6.787 1.00 39.20 ? 180 LEU U N 1 ATOM 2286 C CA . LEU B 2 180 ? 34.246 -14.323 5.968 1.00 38.98 ? 180 LEU U CA 1 ATOM 2287 C C . LEU B 2 180 ? 35.397 -13.725 6.758 1.00 38.88 ? 180 LEU U C 1 ATOM 2288 O O . LEU B 2 180 ? 35.236 -12.706 7.414 1.00 38.95 ? 180 LEU U O 1 ATOM 2289 C CB . LEU B 2 180 ? 33.531 -13.217 5.205 1.00 39.05 ? 180 LEU U CB 1 ATOM 2290 C CG . LEU B 2 180 ? 32.321 -13.648 4.377 1.00 39.57 ? 180 LEU U CG 1 ATOM 2291 C CD1 . LEU B 2 180 ? 31.278 -12.527 4.314 1.00 38.81 ? 180 LEU U CD1 1 ATOM 2292 C CD2 . LEU B 2 180 ? 32.763 -14.137 2.976 1.00 39.64 ? 180 LEU U CD2 1 ATOM 2293 N N . ASP B 2 181 ? 36.561 -14.353 6.683 1.00 38.95 ? 181 ASP U N 1 ATOM 2294 C CA . ASP B 2 181 ? 37.748 -13.836 7.343 1.00 39.37 ? 181 ASP U CA 1 ATOM 2295 C C . ASP B 2 181 ? 38.602 -12.995 6.385 1.00 39.52 ? 181 ASP U C 1 ATOM 2296 O O . ASP B 2 181 ? 38.160 -12.623 5.298 1.00 39.45 ? 181 ASP U O 1 ATOM 2297 C CB . ASP B 2 181 ? 38.570 -14.995 7.909 1.00 39.58 ? 181 ASP U CB 1 ATOM 2298 C CG . ASP B 2 181 ? 39.231 -15.839 6.817 1.00 40.90 ? 181 ASP U CG 1 ATOM 2299 O OD1 . ASP B 2 181 ? 38.501 -16.374 5.953 1.00 42.05 ? 181 ASP U OD1 1 ATOM 2300 O OD2 . ASP B 2 181 ? 40.481 -15.972 6.825 1.00 41.56 ? 181 ASP U OD2 1 ATOM 2301 N N . LEU B 2 182 ? 39.832 -12.697 6.795 1.00 39.88 ? 182 LEU U N 1 ATOM 2302 C CA . LEU B 2 182 ? 40.795 -12.043 5.914 1.00 40.26 ? 182 LEU U CA 1 ATOM 2303 C C . LEU B 2 182 ? 41.241 -12.991 4.785 1.00 40.22 ? 182 LEU U C 1 ATOM 2304 O O . LEU B 2 182 ? 41.069 -12.676 3.606 1.00 40.43 ? 182 LEU U O 1 ATOM 2305 C CB . LEU B 2 182 ? 42.016 -11.513 6.707 1.00 40.48 ? 182 LEU U CB 1 ATOM 2306 C CG . LEU B 2 182 ? 43.288 -12.375 6.911 1.00 40.73 ? 182 LEU U CG 1 ATOM 2307 C CD1 . LEU B 2 182 ? 44.562 -11.533 6.980 1.00 40.40 ? 182 LEU U CD1 1 ATOM 2308 C CD2 . LEU B 2 182 ? 43.184 -13.305 8.128 1.00 41.09 ? 182 LEU U CD2 1 ATOM 2309 N N . GLN B 2 183 ? 41.782 -14.154 5.166 1.00 39.88 ? 183 GLN U N 1 ATOM 2310 C CA . GLN B 2 183 ? 42.462 -15.079 4.257 1.00 39.43 ? 183 GLN U CA 1 ATOM 2311 C C . GLN B 2 183 ? 41.592 -15.596 3.129 1.00 39.26 ? 183 GLN U C 1 ATOM 2312 O O . GLN B 2 183 ? 42.098 -16.105 2.124 1.00 39.25 ? 183 GLN U O 1 ATOM 2313 C CB . GLN B 2 183 ? 43.000 -16.263 5.037 1.00 39.41 ? 183 GLN U CB 1 ATOM 2314 C CG . GLN B 2 183 ? 44.224 -15.956 5.845 1.00 39.22 ? 183 GLN U CG 1 ATOM 2315 C CD . GLN B 2 183 ? 44.623 -17.129 6.696 1.00 39.19 ? 183 GLN U CD 1 ATOM 2316 O OE1 . GLN B 2 183 ? 43.818 -17.658 7.466 1.00 39.08 ? 183 GLN U OE1 1 ATOM 2317 N NE2 . GLN B 2 183 ? 45.870 -17.557 6.558 1.00 39.13 ? 183 GLN U NE2 1 ATOM 2318 N N . SER B 2 184 ? 40.282 -15.472 3.305 1.00 38.88 ? 184 SER U N 1 ATOM 2319 C CA . SER B 2 184 ? 39.330 -15.839 2.272 1.00 38.53 ? 184 SER U CA 1 ATOM 2320 C C . SER B 2 184 ? 39.342 -14.856 1.095 1.00 38.36 ? 184 SER U C 1 ATOM 2321 O O . SER B 2 184 ? 38.551 -14.998 0.164 1.00 38.53 ? 184 SER U O 1 ATOM 2322 C CB . SER B 2 184 ? 37.934 -15.931 2.870 1.00 38.29 ? 184 SER U CB 1 ATOM 2323 O OG . SER B 2 184 ? 37.725 -14.838 3.735 1.00 38.12 ? 184 SER U OG 1 ATOM 2324 N N . PHE B 2 185 ? 40.238 -13.872 1.124 1.00 38.08 ? 185 PHE U N 1 ATOM 2325 C CA . PHE B 2 185 ? 40.308 -12.892 0.039 1.00 37.87 ? 185 PHE U CA 1 ATOM 2326 C C . PHE B 2 185 ? 41.625 -12.902 -0.710 1.00 37.59 ? 185 PHE U C 1 ATOM 2327 O O . PHE B 2 185 ? 42.690 -12.943 -0.090 1.00 37.47 ? 185 PHE U O 1 ATOM 2328 C CB . PHE B 2 185 ? 39.953 -11.490 0.526 1.00 37.92 ? 185 PHE U CB 1 ATOM 2329 C CG . PHE B 2 185 ? 38.514 -11.347 0.881 1.00 38.22 ? 185 PHE U CG 1 ATOM 2330 C CD1 . PHE B 2 185 ? 37.593 -10.946 -0.077 1.00 38.14 ? 185 PHE U CD1 1 ATOM 2331 C CD2 . PHE B 2 185 ? 38.065 -11.659 2.170 1.00 38.71 ? 185 PHE U CD2 1 ATOM 2332 C CE1 . PHE B 2 185 ? 36.240 -10.830 0.246 1.00 38.90 ? 185 PHE U CE1 1 ATOM 2333 C CE2 . PHE B 2 185 ? 36.713 -11.550 2.508 1.00 38.76 ? 185 PHE U CE2 1 ATOM 2334 C CZ . PHE B 2 185 ? 35.797 -11.133 1.546 1.00 38.81 ? 185 PHE U CZ 1 ATOM 2335 N N . PRO B 2 186 ? 41.541 -12.853 -2.054 1.00 37.34 ? 186 PRO U N 1 ATOM 2336 C CA . PRO B 2 186 ? 42.696 -12.945 -2.938 1.00 37.15 ? 186 PRO U CA 1 ATOM 2337 C C . PRO B 2 186 ? 43.503 -11.653 -2.960 1.00 36.94 ? 186 PRO U C 1 ATOM 2338 O O . PRO B 2 186 ? 43.059 -10.672 -3.562 1.00 36.77 ? 186 PRO U O 1 ATOM 2339 C CB . PRO B 2 186 ? 42.062 -13.195 -4.311 1.00 37.27 ? 186 PRO U CB 1 ATOM 2340 C CG . PRO B 2 186 ? 40.705 -12.564 -4.228 1.00 37.22 ? 186 PRO U CG 1 ATOM 2341 C CD . PRO B 2 186 ? 40.276 -12.674 -2.800 1.00 37.23 ? 186 PRO U CD 1 ATOM 2342 N N . PRO B 2 187 ? 44.691 -11.649 -2.321 1.00 36.84 ? 187 PRO U N 1 ATOM 2343 C CA . PRO B 2 187 ? 45.506 -10.433 -2.364 1.00 36.76 ? 187 PRO U CA 1 ATOM 2344 C C . PRO B 2 187 ? 45.559 -9.971 -3.808 1.00 36.63 ? 187 PRO U C 1 ATOM 2345 O O . PRO B 2 187 ? 46.388 -10.454 -4.581 1.00 36.63 ? 187 PRO U O 1 ATOM 2346 C CB . PRO B 2 187 ? 46.893 -10.904 -1.905 1.00 36.80 ? 187 PRO U CB 1 ATOM 2347 C CG . PRO B 2 187 ? 46.660 -12.189 -1.186 1.00 36.96 ? 187 PRO U CG 1 ATOM 2348 C CD . PRO B 2 187 ? 45.421 -12.802 -1.758 1.00 36.85 ? 187 PRO U CD 1 ATOM 2349 N N . ASN B 2 188 ? 44.645 -9.071 -4.166 1.00 36.45 ? 188 ASN U N 1 ATOM 2350 C CA . ASN B 2 188 ? 44.454 -8.661 -5.552 1.00 36.42 ? 188 ASN U CA 1 ATOM 2351 C C . ASN B 2 188 ? 45.714 -8.121 -6.230 1.00 36.63 ? 188 ASN U C 1 ATOM 2352 O O . ASN B 2 188 ? 45.834 -8.183 -7.455 1.00 36.84 ? 188 ASN U O 1 ATOM 2353 C CB . ASN B 2 188 ? 43.316 -7.652 -5.654 1.00 36.25 ? 188 ASN U CB 1 ATOM 2354 C CG . ASN B 2 188 ? 43.551 -6.412 -4.813 1.00 35.60 ? 188 ASN U CG 1 ATOM 2355 O OD1 . ASN B 2 188 ? 44.688 -5.990 -4.587 1.00 34.47 ? 188 ASN U OD1 1 ATOM 2356 N ND2 . ASN B 2 188 ? 42.466 -5.810 -4.360 1.00 34.99 ? 188 ASN U ND2 1 ATOM 2357 N N . GLY B 2 189 ? 46.641 -7.595 -5.426 1.00 36.66 ? 189 GLY U N 1 ATOM 2358 C CA . GLY B 2 189 ? 47.939 -7.126 -5.916 1.00 36.56 ? 189 GLY U CA 1 ATOM 2359 C C . GLY B 2 189 ? 48.101 -5.623 -5.799 1.00 36.55 ? 189 GLY U C 1 ATOM 2360 O O . GLY B 2 189 ? 49.224 -5.106 -5.739 1.00 36.54 ? 189 GLY U O 1 ATOM 2361 N N . PHE B 2 190 ? 46.967 -4.926 -5.776 1.00 36.54 ? 190 PHE U N 1 ATOM 2362 C CA . PHE B 2 190 ? 46.940 -3.469 -5.651 1.00 36.37 ? 190 PHE U CA 1 ATOM 2363 C C . PHE B 2 190 ? 47.140 -3.102 -4.184 1.00 36.13 ? 190 PHE U C 1 ATOM 2364 O O . PHE B 2 190 ? 46.936 -3.935 -3.282 1.00 36.07 ? 190 PHE U O 1 ATOM 2365 C CB . PHE B 2 190 ? 45.626 -2.893 -6.208 1.00 36.38 ? 190 PHE U CB 1 ATOM 2366 C CG . PHE B 2 190 ? 45.180 -3.530 -7.509 1.00 36.76 ? 190 PHE U CG 1 ATOM 2367 C CD1 . PHE B 2 190 ? 45.690 -3.092 -8.731 1.00 37.03 ? 190 PHE U CD1 1 ATOM 2368 C CD2 . PHE B 2 190 ? 44.254 -4.579 -7.508 1.00 36.90 ? 190 PHE U CD2 1 ATOM 2369 C CE1 . PHE B 2 190 ? 45.284 -3.690 -9.932 1.00 37.46 ? 190 PHE U CE1 1 ATOM 2370 C CE2 . PHE B 2 190 ? 43.838 -5.182 -8.702 1.00 36.73 ? 190 PHE U CE2 1 ATOM 2371 C CZ . PHE B 2 190 ? 44.352 -4.736 -9.916 1.00 37.22 ? 190 PHE U CZ 1 ATOM 2372 N N . GLN B 2 191 ? 47.563 -1.867 -3.942 1.00 35.63 ? 191 GLN U N 1 ATOM 2373 C CA . GLN B 2 191 ? 47.910 -1.463 -2.588 1.00 35.17 ? 191 GLN U CA 1 ATOM 2374 C C . GLN B 2 191 ? 47.163 -0.214 -2.124 1.00 34.93 ? 191 GLN U C 1 ATOM 2375 O O . GLN B 2 191 ? 46.580 0.499 -2.939 1.00 34.96 ? 191 GLN U O 1 ATOM 2376 C CB . GLN B 2 191 ? 49.424 -1.278 -2.479 1.00 35.04 ? 191 GLN U CB 1 ATOM 2377 C CG . GLN B 2 191 ? 50.204 -2.502 -2.920 1.00 34.64 ? 191 GLN U CG 1 ATOM 2378 C CD . GLN B 2 191 ? 51.374 -2.808 -2.019 1.00 34.40 ? 191 GLN U CD 1 ATOM 2379 O OE1 . GLN B 2 191 ? 52.522 -2.755 -2.448 1.00 34.61 ? 191 GLN U OE1 1 ATOM 2380 N NE2 . GLN B 2 191 ? 51.092 -3.135 -0.762 1.00 34.11 ? 191 GLN U NE2 1 ATOM 2381 N N . CYS B 2 192 ? 47.166 0.022 -0.810 1.00 34.52 ? 192 CYS U N 1 ATOM 2382 C CA . CYS B 2 192 ? 46.699 1.288 -0.223 1.00 34.02 ? 192 CYS U CA 1 ATOM 2383 C C . CYS B 2 192 ? 47.551 1.715 0.993 1.00 33.96 ? 192 CYS U C 1 ATOM 2384 O O . CYS B 2 192 ? 48.625 1.156 1.233 1.00 33.79 ? 192 CYS U O 1 ATOM 2385 C CB . CYS B 2 192 ? 45.201 1.219 0.122 1.00 33.77 ? 192 CYS U CB 1 ATOM 2386 S SG . CYS B 2 192 ? 44.058 1.511 -1.280 1.00 32.74 ? 192 CYS U SG 1 ATOM 2387 N N . TYR B 2 193 ? 47.078 2.716 1.735 1.00 33.96 ? 193 TYR U N 1 ATOM 2388 C CA . TYR B 2 193 ? 47.719 3.147 2.982 1.00 34.02 ? 193 TYR U CA 1 ATOM 2389 C C . TYR B 2 193 ? 46.793 2.958 4.188 1.00 34.09 ? 193 TYR U C 1 ATOM 2390 O O . TYR B 2 193 ? 45.573 2.960 4.042 1.00 34.11 ? 193 TYR U O 1 ATOM 2391 C CB . TYR B 2 193 ? 48.133 4.613 2.887 1.00 34.06 ? 193 TYR U CB 1 ATOM 2392 C CG . TYR B 2 193 ? 49.245 4.894 1.905 1.00 33.92 ? 193 TYR U CG 1 ATOM 2393 C CD1 . TYR B 2 193 ? 50.532 5.200 2.351 1.00 33.46 ? 193 TYR U CD1 1 ATOM 2394 C CD2 . TYR B 2 193 ? 49.009 4.868 0.532 1.00 33.60 ? 193 TYR U CD2 1 ATOM 2395 C CE1 . TYR B 2 193 ? 51.552 5.469 1.453 1.00 33.46 ? 193 TYR U CE1 1 ATOM 2396 C CE2 . TYR B 2 193 ? 50.022 5.128 -0.375 1.00 33.80 ? 193 TYR U CE2 1 ATOM 2397 C CZ . TYR B 2 193 ? 51.291 5.428 0.089 1.00 33.56 ? 193 TYR U CZ 1 ATOM 2398 O OH . TYR B 2 193 ? 52.291 5.694 -0.817 1.00 33.27 ? 193 TYR U OH 1 ATOM 2399 N N . SER B 2 194 ? 47.381 2.798 5.374 1.00 34.16 ? 194 SER U N 1 ATOM 2400 C CA . SER B 2 194 ? 46.622 2.662 6.623 1.00 34.11 ? 194 SER U CA 1 ATOM 2401 C C . SER B 2 194 ? 47.149 3.656 7.666 1.00 34.21 ? 194 SER U C 1 ATOM 2402 O O . SER B 2 194 ? 48.321 3.604 8.044 1.00 34.24 ? 194 SER U O 1 ATOM 2403 C CB . SER B 2 194 ? 46.714 1.222 7.133 1.00 33.96 ? 194 SER U CB 1 ATOM 2404 O OG . SER B 2 194 ? 45.895 1.011 8.265 1.00 33.75 ? 194 SER U OG 1 ATOM 2405 N N . CYS B 2 195 ? 46.295 4.570 8.117 1.00 34.32 ? 195 CYS U N 1 ATOM 2406 C CA . CYS B 2 195 ? 46.733 5.610 9.047 1.00 34.76 ? 195 CYS U CA 1 ATOM 2407 C C . CYS B 2 195 ? 45.742 5.918 10.171 1.00 35.03 ? 195 CYS U C 1 ATOM 2408 O O . CYS B 2 195 ? 44.561 6.191 9.906 1.00 35.18 ? 195 CYS U O 1 ATOM 2409 C CB . CYS B 2 195 ? 47.081 6.902 8.299 1.00 34.71 ? 195 CYS U CB 1 ATOM 2410 S SG . CYS B 2 195 ? 46.893 8.397 9.326 1.00 35.12 ? 195 CYS U SG 1 ATOM 2411 N N . GLU B 2 196 ? 46.244 5.863 11.416 1.00 35.23 ? 196 GLU U N 1 ATOM 2412 C CA . GLU B 2 196 ? 45.503 6.256 12.649 1.00 35.21 ? 196 GLU U CA 1 ATOM 2413 C C . GLU B 2 196 ? 46.409 6.612 13.866 1.00 35.11 ? 196 GLU U C 1 ATOM 2414 O O . GLU B 2 196 ? 46.692 5.771 14.734 1.00 34.88 ? 196 GLU U O 1 ATOM 2415 C CB . GLU B 2 196 ? 44.389 5.247 13.034 1.00 35.09 ? 196 GLU U CB 1 ATOM 2416 C CG . GLU B 2 196 ? 44.652 3.769 12.699 1.00 35.20 ? 196 GLU U CG 1 ATOM 2417 C CD . GLU B 2 196 ? 44.190 3.369 11.291 1.00 35.04 ? 196 GLU U CD 1 ATOM 2418 O OE1 . GLU B 2 196 ? 42.981 3.465 11.005 1.00 34.72 ? 196 GLU U OE1 1 ATOM 2419 O OE2 . GLU B 2 196 ? 45.036 2.943 10.471 1.00 34.74 ? 196 GLU U OE2 1 ATOM 2420 N N . GLY B 2 197 ? 46.851 7.873 13.894 1.00 35.05 ? 197 GLY U N 1 ATOM 2421 C CA . GLY B 2 197 ? 47.608 8.468 15.006 1.00 34.90 ? 197 GLY U CA 1 ATOM 2422 C C . GLY B 2 197 ? 46.796 9.566 15.683 1.00 34.88 ? 197 GLY U C 1 ATOM 2423 O O . GLY B 2 197 ? 46.090 9.286 16.653 1.00 34.92 ? 197 GLY U O 1 ATOM 2424 N N . ASN B 2 198 ? 46.892 10.805 15.170 1.00 34.85 ? 198 ASN U N 1 ATOM 2425 C CA . ASN B 2 198 ? 46.045 11.964 15.603 1.00 34.57 ? 198 ASN U CA 1 ATOM 2426 C C . ASN B 2 198 ? 45.668 13.024 14.528 1.00 34.51 ? 198 ASN U C 1 ATOM 2427 O O . ASN B 2 198 ? 44.524 13.050 14.045 1.00 34.49 ? 198 ASN U O 1 ATOM 2428 C CB . ASN B 2 198 ? 46.639 12.651 16.838 1.00 34.32 ? 198 ASN U CB 1 ATOM 2429 C CG . ASN B 2 198 ? 46.362 11.886 18.101 1.00 33.68 ? 198 ASN U CG 1 ATOM 2430 O OD1 . ASN B 2 198 ? 45.260 11.941 18.643 1.00 32.80 ? 198 ASN U OD1 1 ATOM 2431 N ND2 . ASN B 2 198 ? 47.354 11.139 18.567 1.00 33.00 ? 198 ASN U ND2 1 ATOM 2432 N N . ASN B 2 199 ? 46.624 13.895 14.187 1.00 34.35 ? 199 ASN U N 1 ATOM 2433 C CA . ASN B 2 199 ? 46.466 14.933 13.156 1.00 34.15 ? 199 ASN U CA 1 ATOM 2434 C C . ASN B 2 199 ? 47.756 15.167 12.349 1.00 34.43 ? 199 ASN U C 1 ATOM 2435 O O . ASN B 2 199 ? 48.709 15.756 12.871 1.00 34.55 ? 199 ASN U O 1 ATOM 2436 C CB . ASN B 2 199 ? 46.049 16.264 13.795 1.00 33.83 ? 199 ASN U CB 1 ATOM 2437 C CG . ASN B 2 199 ? 44.555 16.392 13.993 1.00 32.89 ? 199 ASN U CG 1 ATOM 2438 O OD1 . ASN B 2 199 ? 43.924 17.270 13.409 1.00 31.27 ? 199 ASN U OD1 1 ATOM 2439 N ND2 . ASN B 2 199 ? 43.984 15.539 14.838 1.00 32.25 ? 199 ASN U ND2 1 ATOM 2440 N N . THR B 2 200 ? 47.782 14.699 11.093 1.00 34.62 ? 200 THR U N 1 ATOM 2441 C CA . THR B 2 200 ? 48.894 14.921 10.114 1.00 34.72 ? 200 THR U CA 1 ATOM 2442 C C . THR B 2 200 ? 50.271 14.260 10.417 1.00 34.87 ? 200 THR U C 1 ATOM 2443 O O . THR B 2 200 ? 50.909 13.719 9.504 1.00 34.83 ? 200 THR U O 1 ATOM 2444 C CB . THR B 2 200 ? 49.095 16.437 9.738 1.00 34.66 ? 200 THR U CB 1 ATOM 2445 O OG1 . THR B 2 200 ? 47.831 17.113 9.708 1.00 34.36 ? 200 THR U OG1 1 ATOM 2446 C CG2 . THR B 2 200 ? 49.770 16.579 8.375 1.00 34.49 ? 200 THR U CG2 1 ATOM 2447 N N . LEU B 2 201 ? 50.725 14.330 11.675 1.00 35.01 ? 201 LEU U N 1 ATOM 2448 C CA . LEU B 2 201 ? 52.025 13.759 12.102 1.00 35.05 ? 201 LEU U CA 1 ATOM 2449 C C . LEU B 2 201 ? 51.940 12.593 13.122 1.00 35.07 ? 201 LEU U C 1 ATOM 2450 O O . LEU B 2 201 ? 52.918 12.309 13.835 1.00 35.04 ? 201 LEU U O 1 ATOM 2451 C CB . LEU B 2 201 ? 52.984 14.857 12.618 1.00 34.99 ? 201 LEU U CB 1 ATOM 2452 C CG . LEU B 2 201 ? 53.995 15.531 11.672 1.00 34.93 ? 201 LEU U CG 1 ATOM 2453 C CD1 . LEU B 2 201 ? 54.733 16.681 12.367 1.00 34.76 ? 201 LEU U CD1 1 ATOM 2454 C CD2 . LEU B 2 201 ? 54.997 14.531 11.101 1.00 34.76 ? 201 LEU U CD2 1 ATOM 2455 N N . GLY B 2 202 ? 50.778 11.936 13.193 1.00 34.94 ? 202 GLY U N 1 ATOM 2456 C CA . GLY B 2 202 ? 50.646 10.654 13.895 1.00 34.65 ? 202 GLY U CA 1 ATOM 2457 C C . GLY B 2 202 ? 51.048 9.574 12.912 1.00 34.48 ? 202 GLY U C 1 ATOM 2458 O O . GLY B 2 202 ? 51.628 8.549 13.274 1.00 34.36 ? 202 GLY U O 1 ATOM 2459 N N . CYS B 2 203 ? 50.734 9.844 11.650 1.00 34.39 ? 203 CYS U N 1 ATOM 2460 C CA . CYS B 2 203 ? 51.098 9.009 10.525 1.00 34.33 ? 203 CYS U CA 1 ATOM 2461 C C . CYS B 2 203 ? 51.652 9.913 9.425 1.00 34.14 ? 203 CYS U C 1 ATOM 2462 O O . CYS B 2 203 ? 51.319 11.098 9.361 1.00 34.12 ? 203 CYS U O 1 ATOM 2463 C CB . CYS B 2 203 ? 49.858 8.283 10.012 1.00 34.43 ? 203 CYS U CB 1 ATOM 2464 S SG . CYS B 2 203 ? 48.671 9.367 9.160 1.00 34.88 ? 203 CYS U SG 1 ATOM 2465 N N . SER B 2 204 ? 52.495 9.354 8.564 1.00 33.90 ? 204 SER U N 1 ATOM 2466 C CA . SER B 2 204 ? 53.028 10.076 7.411 1.00 33.67 ? 204 SER U CA 1 ATOM 2467 C C . SER B 2 204 ? 53.574 9.057 6.421 1.00 33.65 ? 204 SER U C 1 ATOM 2468 O O . SER B 2 204 ? 53.092 7.927 6.364 1.00 33.55 ? 204 SER U O 1 ATOM 2469 C CB . SER B 2 204 ? 54.130 11.057 7.841 1.00 33.65 ? 204 SER U CB 1 ATOM 2470 O OG . SER B 2 204 ? 53.605 12.142 8.587 1.00 33.22 ? 204 SER U OG 1 ATOM 2471 N N . SER B 2 205 ? 54.575 9.465 5.640 1.00 33.73 ? 205 SER U N 1 ATOM 2472 C CA . SER B 2 205 ? 55.420 8.535 4.884 1.00 33.74 ? 205 SER U CA 1 ATOM 2473 C C . SER B 2 205 ? 56.348 7.802 5.859 1.00 33.70 ? 205 SER U C 1 ATOM 2474 O O . SER B 2 205 ? 57.248 7.059 5.442 1.00 33.71 ? 205 SER U O 1 ATOM 2475 C CB . SER B 2 205 ? 56.262 9.286 3.842 1.00 33.75 ? 205 SER U CB 1 ATOM 2476 O OG . SER B 2 205 ? 55.454 9.993 2.917 1.00 33.80 ? 205 SER U OG 1 ATOM 2477 N N . GLU B 2 206 ? 56.115 8.025 7.156 1.00 33.59 ? 206 GLU U N 1 ATOM 2478 C CA . GLU B 2 206 ? 56.973 7.514 8.233 1.00 33.33 ? 206 GLU U CA 1 ATOM 2479 C C . GLU B 2 206 ? 56.238 6.580 9.226 1.00 33.11 ? 206 GLU U C 1 ATOM 2480 O O . GLU B 2 206 ? 56.724 5.481 9.517 1.00 33.23 ? 206 GLU U O 1 ATOM 2481 C CB . GLU B 2 206 ? 57.697 8.673 8.963 1.00 33.35 ? 206 GLU U CB 1 ATOM 2482 C CG . GLU B 2 206 ? 58.766 9.413 8.119 1.00 32.81 ? 206 GLU U CG 1 ATOM 2483 C CD . GLU B 2 206 ? 59.595 10.432 8.913 1.00 32.06 ? 206 GLU U CD 1 ATOM 2484 O OE1 . GLU B 2 206 ? 59.224 10.764 10.059 1.00 31.71 ? 206 GLU U OE1 1 ATOM 2485 O OE2 . GLU B 2 206 ? 60.622 10.910 8.381 1.00 31.52 ? 206 GLU U OE2 1 ATOM 2486 N N . GLU B 2 207 ? 55.083 7.002 9.743 1.00 32.63 ? 207 GLU U N 1 ATOM 2487 C CA . GLU B 2 207 ? 54.310 6.149 10.657 1.00 32.24 ? 207 GLU U CA 1 ATOM 2488 C C . GLU B 2 207 ? 52.942 5.754 10.094 1.00 32.05 ? 207 GLU U C 1 ATOM 2489 O O . GLU B 2 207 ? 51.923 5.790 10.787 1.00 31.92 ? 207 GLU U O 1 ATOM 2490 C CB . GLU B 2 207 ? 54.219 6.756 12.067 1.00 32.25 ? 207 GLU U CB 1 ATOM 2491 C CG . GLU B 2 207 ? 54.929 5.936 13.163 1.00 31.97 ? 207 GLU U CG 1 ATOM 2492 C CD . GLU B 2 207 ? 56.449 5.853 13.008 1.00 31.85 ? 207 GLU U CD 1 ATOM 2493 O OE1 . GLU B 2 207 ? 56.983 4.724 12.940 1.00 31.78 ? 207 GLU U OE1 1 ATOM 2494 O OE2 . GLU B 2 207 ? 57.115 6.909 12.967 1.00 31.85 ? 207 GLU U OE2 1 ATOM 2495 N N . ALA B 2 208 ? 52.963 5.384 8.815 1.00 31.90 ? 208 ALA U N 1 ATOM 2496 C CA . ALA B 2 208 ? 51.871 4.707 8.105 1.00 31.67 ? 208 ALA U CA 1 ATOM 2497 C C . ALA B 2 208 ? 52.498 4.007 6.897 1.00 31.53 ? 208 ALA U C 1 ATOM 2498 O O . ALA B 2 208 ? 53.343 4.593 6.203 1.00 31.70 ? 208 ALA U O 1 ATOM 2499 C CB . ALA B 2 208 ? 50.813 5.700 7.652 1.00 31.62 ? 208 ALA U CB 1 ATOM 2500 N N . SER B 2 209 ? 52.106 2.755 6.653 1.00 31.14 ? 209 SER U N 1 ATOM 2501 C CA . SER B 2 209 ? 52.702 1.958 5.566 1.00 30.67 ? 209 SER U CA 1 ATOM 2502 C C . SER B 2 209 ? 51.686 1.484 4.520 1.00 30.27 ? 209 SER U C 1 ATOM 2503 O O . SER B 2 209 ? 50.475 1.634 4.698 1.00 30.22 ? 209 SER U O 1 ATOM 2504 C CB . SER B 2 209 ? 53.494 0.770 6.132 1.00 30.72 ? 209 SER U CB 1 ATOM 2505 O OG . SER B 2 209 ? 54.754 1.180 6.641 1.00 30.61 ? 209 SER U OG 1 ATOM 2506 N N . LEU B 2 210 ? 52.201 0.916 3.430 1.00 29.76 ? 210 LEU U N 1 ATOM 2507 C CA . LEU B 2 210 ? 51.381 0.382 2.349 1.00 29.31 ? 210 LEU U CA 1 ATOM 2508 C C . LEU B 2 210 ? 50.775 -0.948 2.735 1.00 28.96 ? 210 LEU U C 1 ATOM 2509 O O . LEU B 2 210 ? 51.497 -1.892 3.055 1.00 28.95 ? 210 LEU U O 1 ATOM 2510 C CB . LEU B 2 210 ? 52.221 0.169 1.087 1.00 29.42 ? 210 LEU U CB 1 ATOM 2511 C CG . LEU B 2 210 ? 52.510 1.297 0.089 1.00 29.68 ? 210 LEU U CG 1 ATOM 2512 C CD1 . LEU B 2 210 ? 51.236 1.785 -0.603 1.00 29.70 ? 210 LEU U CD1 1 ATOM 2513 C CD2 . LEU B 2 210 ? 53.278 2.448 0.735 1.00 30.24 ? 210 LEU U CD2 1 ATOM 2514 N N . ILE B 2 211 ? 49.450 -1.026 2.704 1.00 28.62 ? 211 ILE U N 1 ATOM 2515 C CA . ILE B 2 211 ? 48.769 -2.304 2.900 1.00 28.21 ? 211 ILE U CA 1 ATOM 2516 C C . ILE B 2 211 ? 48.755 -3.010 1.568 1.00 27.99 ? 211 ILE U C 1 ATOM 2517 O O . ILE B 2 211 ? 48.854 -2.364 0.523 1.00 27.89 ? 211 ILE U O 1 ATOM 2518 C CB . ILE B 2 211 ? 47.300 -2.176 3.454 1.00 28.17 ? 211 ILE U CB 1 ATOM 2519 C CG1 . ILE B 2 211 ? 46.382 -1.419 2.483 1.00 28.00 ? 211 ILE U CG1 1 ATOM 2520 C CG2 . ILE B 2 211 ? 47.285 -1.556 4.856 1.00 28.08 ? 211 ILE U CG2 1 ATOM 2521 C CD1 . ILE B 2 211 ? 44.930 -1.357 2.925 1.00 27.46 ? 211 ILE U CD1 1 ATOM 2522 N N . ASN B 2 212 ? 48.661 -4.333 1.602 1.00 27.77 ? 212 ASN U N 1 ATOM 2523 C CA . ASN B 2 212 ? 48.447 -5.071 0.378 1.00 27.52 ? 212 ASN U CA 1 ATOM 2524 C C . ASN B 2 212 ? 46.969 -5.334 0.263 1.00 27.53 ? 212 ASN U C 1 ATOM 2525 O O . ASN B 2 212 ? 46.405 -6.100 1.049 1.00 27.36 ? 212 ASN U O 1 ATOM 2526 C CB . ASN B 2 212 ? 49.252 -6.363 0.344 1.00 27.35 ? 212 ASN U CB 1 ATOM 2527 C CG . ASN B 2 212 ? 49.751 -6.680 -1.039 1.00 26.64 ? 212 ASN U CG 1 ATOM 2528 O OD1 . ASN B 2 212 ? 48.973 -6.780 -1.989 1.00 26.00 ? 212 ASN U OD1 1 ATOM 2529 N ND2 . ASN B 2 212 ? 51.057 -6.817 -1.169 1.00 25.88 ? 212 ASN U ND2 1 ATOM 2530 N N . CYS B 2 213 ? 46.344 -4.662 -0.702 1.00 27.65 ? 213 CYS U N 1 ATOM 2531 C CA . CYS B 2 213 ? 44.888 -4.674 -0.834 1.00 27.91 ? 213 CYS U CA 1 ATOM 2532 C C . CYS B 2 213 ? 44.396 -6.085 -1.106 1.00 27.76 ? 213 CYS U C 1 ATOM 2533 O O . CYS B 2 213 ? 45.083 -6.865 -1.782 1.00 28.08 ? 213 CYS U O 1 ATOM 2534 C CB . CYS B 2 213 ? 44.430 -3.718 -1.943 1.00 28.04 ? 213 CYS U CB 1 ATOM 2535 S SG . CYS B 2 213 ? 44.205 -1.969 -1.453 1.00 28.75 ? 213 CYS U SG 1 ATOM 2536 N N . ARG B 2 214 ? 43.220 -6.415 -0.578 1.00 27.33 ? 214 ARG U N 1 ATOM 2537 C CA . ARG B 2 214 ? 42.701 -7.779 -0.694 1.00 27.10 ? 214 ARG U CA 1 ATOM 2538 C C . ARG B 2 214 ? 41.409 -7.933 -1.503 1.00 27.14 ? 214 ARG U C 1 ATOM 2539 O O . ARG B 2 214 ? 40.323 -7.550 -1.069 1.00 27.12 ? 214 ARG U O 1 ATOM 2540 C CB . ARG B 2 214 ? 42.578 -8.450 0.681 1.00 26.84 ? 214 ARG U CB 1 ATOM 2541 C CG . ARG B 2 214 ? 43.912 -8.867 1.282 1.00 26.15 ? 214 ARG U CG 1 ATOM 2542 C CD . ARG B 2 214 ? 43.797 -10.238 1.913 1.00 24.96 ? 214 ARG U CD 1 ATOM 2543 N NE . ARG B 2 214 ? 44.975 -10.588 2.698 1.00 23.62 ? 214 ARG U NE 1 ATOM 2544 C CZ . ARG B 2 214 ? 45.082 -11.693 3.427 1.00 23.40 ? 214 ARG U CZ 1 ATOM 2545 N NH1 . ARG B 2 214 ? 44.089 -12.573 3.470 1.00 22.22 ? 214 ARG U NH1 1 ATOM 2546 N NH2 . ARG B 2 214 ? 46.193 -11.920 4.114 1.00 23.90 ? 214 ARG U NH2 1 ATOM 2547 N N . GLY B 2 215 ? 41.553 -8.506 -2.693 1.00 27.32 ? 215 GLY U N 1 ATOM 2548 C CA . GLY B 2 215 ? 40.412 -8.898 -3.514 1.00 27.34 ? 215 GLY U CA 1 ATOM 2549 C C . GLY B 2 215 ? 39.485 -7.761 -3.894 1.00 27.06 ? 215 GLY U C 1 ATOM 2550 O O . GLY B 2 215 ? 39.922 -6.785 -4.516 1.00 27.10 ? 215 GLY U O 1 ATOM 2551 N N . PRO B 2 216 ? 38.198 -7.880 -3.520 1.00 26.70 ? 216 PRO U N 1 ATOM 2552 C CA . PRO B 2 216 ? 37.199 -6.900 -3.932 1.00 26.67 ? 216 PRO U CA 1 ATOM 2553 C C . PRO B 2 216 ? 37.563 -5.449 -3.591 1.00 26.74 ? 216 PRO U C 1 ATOM 2554 O O . PRO B 2 216 ? 37.099 -4.530 -4.271 1.00 27.09 ? 216 PRO U O 1 ATOM 2555 C CB . PRO B 2 216 ? 35.941 -7.365 -3.202 1.00 26.46 ? 216 PRO U CB 1 ATOM 2556 C CG . PRO B 2 216 ? 36.133 -8.844 -3.109 1.00 26.40 ? 216 PRO U CG 1 ATOM 2557 C CD . PRO B 2 216 ? 37.586 -9.013 -2.805 1.00 26.38 ? 216 PRO U CD 1 ATOM 2558 N N . MET B 2 217 ? 38.395 -5.243 -2.572 1.00 26.47 ? 217 MET U N 1 ATOM 2559 C CA . MET B 2 217 ? 38.895 -3.907 -2.257 1.00 26.18 ? 217 MET U CA 1 ATOM 2560 C C . MET B 2 217 ? 39.929 -3.475 -3.291 1.00 25.98 ? 217 MET U C 1 ATOM 2561 O O . MET B 2 217 ? 40.929 -4.162 -3.510 1.00 26.00 ? 217 MET U O 1 ATOM 2562 C CB . MET B 2 217 ? 39.513 -3.877 -0.859 1.00 26.34 ? 217 MET U CB 1 ATOM 2563 C CG . MET B 2 217 ? 38.557 -3.577 0.274 1.00 26.69 ? 217 MET U CG 1 ATOM 2564 S SD . MET B 2 217 ? 37.332 -4.862 0.583 1.00 26.95 ? 217 MET U SD 1 ATOM 2565 C CE . MET B 2 217 ? 36.067 -4.416 -0.601 1.00 26.38 ? 217 MET U CE 1 ATOM 2566 N N . ASN B 2 218 ? 39.680 -2.338 -3.930 1.00 25.64 ? 218 ASN U N 1 ATOM 2567 C CA . ASN B 2 218 ? 40.600 -1.806 -4.932 1.00 25.39 ? 218 ASN U CA 1 ATOM 2568 C C . ASN B 2 218 ? 40.604 -0.281 -4.989 1.00 25.21 ? 218 ASN U C 1 ATOM 2569 O O . ASN B 2 218 ? 41.345 0.314 -5.763 1.00 25.32 ? 218 ASN U O 1 ATOM 2570 C CB . ASN B 2 218 ? 40.296 -2.398 -6.316 1.00 25.50 ? 218 ASN U CB 1 ATOM 2571 C CG . ASN B 2 218 ? 38.821 -2.295 -6.693 1.00 25.86 ? 218 ASN U CG 1 ATOM 2572 O OD1 . ASN B 2 218 ? 38.166 -1.278 -6.452 1.00 26.54 ? 218 ASN U OD1 1 ATOM 2573 N ND2 . ASN B 2 218 ? 38.296 -3.355 -7.292 1.00 25.74 ? 218 ASN U ND2 1 ATOM 2574 N N . GLN B 2 219 ? 39.766 0.343 -4.167 1.00 25.21 ? 219 GLN U N 1 ATOM 2575 C CA . GLN B 2 219 ? 39.684 1.797 -4.084 1.00 24.84 ? 219 GLN U CA 1 ATOM 2576 C C . GLN B 2 219 ? 40.500 2.299 -2.913 1.00 24.58 ? 219 GLN U C 1 ATOM 2577 O O . GLN B 2 219 ? 40.257 1.911 -1.773 1.00 24.35 ? 219 GLN U O 1 ATOM 2578 C CB . GLN B 2 219 ? 38.231 2.245 -3.913 1.00 24.95 ? 219 GLN U CB 1 ATOM 2579 C CG . GLN B 2 219 ? 37.316 1.987 -5.108 1.00 24.75 ? 219 GLN U CG 1 ATOM 2580 C CD . GLN B 2 219 ? 37.470 3.026 -6.181 1.00 24.30 ? 219 GLN U CD 1 ATOM 2581 O OE1 . GLN B 2 219 ? 38.407 2.969 -6.967 1.00 25.25 ? 219 GLN U OE1 1 ATOM 2582 N NE2 . GLN B 2 219 ? 36.551 3.990 -6.223 1.00 23.82 ? 219 GLN U NE2 1 ATOM 2583 N N . CYS B 2 220 ? 41.473 3.153 -3.201 1.00 24.58 ? 220 CYS U N 1 ATOM 2584 C CA . CYS B 2 220 ? 42.218 3.817 -2.156 1.00 25.07 ? 220 CYS U CA 1 ATOM 2585 C C . CYS B 2 220 ? 41.440 5.015 -1.658 1.00 24.60 ? 220 CYS U C 1 ATOM 2586 O O . CYS B 2 220 ? 40.952 5.822 -2.456 1.00 24.68 ? 220 CYS U O 1 ATOM 2587 C CB . CYS B 2 220 ? 43.594 4.230 -2.635 1.00 25.47 ? 220 CYS U CB 1 ATOM 2588 S SG . CYS B 2 220 ? 44.922 3.043 -2.319 1.00 28.73 ? 220 CYS U SG 1 ATOM 2589 N N . LEU B 2 221 ? 41.357 5.119 -0.330 1.00 24.04 ? 221 LEU U N 1 ATOM 2590 C CA . LEU B 2 221 ? 40.398 5.969 0.354 1.00 23.22 ? 221 LEU U CA 1 ATOM 2591 C C . LEU B 2 221 ? 40.973 6.700 1.582 1.00 22.79 ? 221 LEU U C 1 ATOM 2592 O O . LEU B 2 221 ? 41.850 6.159 2.256 1.00 22.86 ? 221 LEU U O 1 ATOM 2593 C CB . LEU B 2 221 ? 39.213 5.099 0.762 1.00 23.11 ? 221 LEU U CB 1 ATOM 2594 C CG . LEU B 2 221 ? 38.609 5.279 2.151 1.00 23.43 ? 221 LEU U CG 1 ATOM 2595 C CD1 . LEU B 2 221 ? 37.131 4.966 2.112 1.00 23.77 ? 221 LEU U CD1 1 ATOM 2596 C CD2 . LEU B 2 221 ? 39.337 4.431 3.191 1.00 23.64 ? 221 LEU U CD2 1 ATOM 2597 N N . VAL B 2 222 ? 40.456 7.914 1.849 1.00 21.93 ? 222 VAL U N 1 ATOM 2598 C CA . VAL B 2 222 ? 40.757 8.741 3.044 1.00 20.61 ? 222 VAL U CA 1 ATOM 2599 C C . VAL B 2 222 ? 39.470 9.162 3.749 1.00 19.96 ? 222 VAL U C 1 ATOM 2600 O O . VAL B 2 222 ? 38.411 9.188 3.129 1.00 20.05 ? 222 VAL U O 1 ATOM 2601 C CB . VAL B 2 222 ? 41.485 10.059 2.689 1.00 20.54 ? 222 VAL U CB 1 ATOM 2602 C CG1 . VAL B 2 222 ? 42.919 9.802 2.229 1.00 20.60 ? 222 VAL U CG1 1 ATOM 2603 C CG2 . VAL B 2 222 ? 40.687 10.854 1.661 1.00 19.99 ? 222 VAL U CG2 1 ATOM 2604 N N . ALA B 2 223 ? 39.576 9.536 5.027 1.00 18.89 ? 223 ALA U N 1 ATOM 2605 C CA . ALA B 2 223 ? 38.420 9.920 5.844 1.00 17.62 ? 223 ALA U CA 1 ATOM 2606 C C . ALA B 2 223 ? 38.806 10.920 6.925 1.00 16.86 ? 223 ALA U C 1 ATOM 2607 O O . ALA B 2 223 ? 39.947 10.929 7.375 1.00 16.60 ? 223 ALA U O 1 ATOM 2608 C CB . ALA B 2 223 ? 37.809 8.690 6.472 1.00 17.45 ? 223 ALA U CB 1 ATOM 2609 N N . THR B 2 224 ? 37.857 11.751 7.354 1.00 16.11 ? 224 THR U N 1 ATOM 2610 C CA . THR B 2 224 ? 38.164 12.804 8.329 1.00 15.70 ? 224 THR U CA 1 ATOM 2611 C C . THR B 2 224 ? 36.923 13.332 9.078 1.00 15.14 ? 224 THR U C 1 ATOM 2612 O O . THR B 2 224 ? 35.808 12.928 8.775 1.00 15.28 ? 224 THR U O 1 ATOM 2613 C CB . THR B 2 224 ? 38.911 13.968 7.645 1.00 15.95 ? 224 THR U CB 1 ATOM 2614 O OG1 . THR B 2 224 ? 39.401 13.539 6.365 1.00 16.33 ? 224 THR U OG1 1 ATOM 2615 C CG2 . THR B 2 224 ? 40.078 14.451 8.511 1.00 15.99 ? 224 THR U CG2 1 ATOM 2616 N N . GLY B 2 225 ? 37.127 14.209 10.066 1.00 14.36 ? 225 GLY U N 1 ATOM 2617 C CA . GLY B 2 225 ? 36.033 14.815 10.832 1.00 13.31 ? 225 GLY U CA 1 ATOM 2618 C C . GLY B 2 225 ? 36.525 15.537 12.081 1.00 12.89 ? 225 GLY U C 1 ATOM 2619 O O . GLY B 2 225 ? 37.509 15.114 12.697 1.00 12.71 ? 225 GLY U O 1 ATOM 2620 N N . LEU B 2 226 ? 35.843 16.633 12.438 1.00 12.41 ? 226 LEU U N 1 ATOM 2621 C CA . LEU B 2 226 ? 36.099 17.399 13.671 1.00 11.82 ? 226 LEU U CA 1 ATOM 2622 C C . LEU B 2 226 ? 34.988 17.168 14.676 1.00 11.72 ? 226 LEU U C 1 ATOM 2623 O O . LEU B 2 226 ? 35.251 16.803 15.821 1.00 11.69 ? 226 LEU U O 1 ATOM 2624 C CB . LEU B 2 226 ? 36.209 18.911 13.400 1.00 11.67 ? 226 LEU U CB 1 ATOM 2625 C CG . LEU B 2 226 ? 37.497 19.751 13.577 1.00 10.80 ? 226 LEU U CG 1 ATOM 2626 C CD1 . LEU B 2 226 ? 37.973 19.907 15.042 1.00 9.08 ? 226 LEU U CD1 1 ATOM 2627 C CD2 . LEU B 2 226 ? 38.616 19.240 12.680 1.00 10.17 ? 226 LEU U CD2 1 ATOM 2628 N N . ARG B 2 232 ? 39.875 14.891 18.703 1.00 19.55 ? 232 ARG U N 1 ATOM 2629 C CA . ARG B 2 232 ? 39.037 15.943 18.137 1.00 19.67 ? 232 ARG U CA 1 ATOM 2630 C C . ARG B 2 232 ? 38.862 15.768 16.624 1.00 20.09 ? 232 ARG U C 1 ATOM 2631 O O . ARG B 2 232 ? 37.732 15.637 16.132 1.00 19.95 ? 232 ARG U O 1 ATOM 2632 C CB . ARG B 2 232 ? 39.589 17.327 18.507 1.00 19.36 ? 232 ARG U CB 1 ATOM 2633 C CG . ARG B 2 232 ? 39.420 17.659 19.987 1.00 18.25 ? 232 ARG U CG 1 ATOM 2634 C CD . ARG B 2 232 ? 40.334 18.758 20.399 1.00 17.20 ? 232 ARG U CD 1 ATOM 2635 N NE . ARG B 2 232 ? 40.185 19.922 19.533 1.00 17.55 ? 232 ARG U NE 1 ATOM 2636 C CZ . ARG B 2 232 ? 40.734 21.114 19.764 1.00 17.41 ? 232 ARG U CZ 1 ATOM 2637 N NH1 . ARG B 2 232 ? 41.476 21.312 20.845 1.00 17.56 ? 232 ARG U NH1 1 ATOM 2638 N NH2 . ARG B 2 232 ? 40.537 22.116 18.914 1.00 16.98 ? 232 ARG U NH2 1 ATOM 2639 N N . SER B 2 233 ? 39.982 15.743 15.900 1.00 20.57 ? 233 SER U N 1 ATOM 2640 C CA . SER B 2 233 ? 39.967 15.500 14.463 1.00 20.96 ? 233 SER U CA 1 ATOM 2641 C C . SER B 2 233 ? 40.588 14.151 14.126 1.00 21.45 ? 233 SER U C 1 ATOM 2642 O O . SER B 2 233 ? 41.812 14.009 14.044 1.00 21.26 ? 233 SER U O 1 ATOM 2643 C CB . SER B 2 233 ? 40.672 16.622 13.708 1.00 20.87 ? 233 SER U CB 1 ATOM 2644 O OG . SER B 2 233 ? 40.386 16.535 12.326 1.00 20.45 ? 233 SER U OG 1 ATOM 2645 N N . TYR B 2 234 ? 39.727 13.159 13.940 1.00 22.27 ? 234 TYR U N 1 ATOM 2646 C CA . TYR B 2 234 ? 40.180 11.809 13.617 1.00 23.17 ? 234 TYR U CA 1 ATOM 2647 C C . TYR B 2 234 ? 40.163 11.556 12.116 1.00 22.84 ? 234 TYR U C 1 ATOM 2648 O O . TYR B 2 234 ? 39.318 12.103 11.407 1.00 22.72 ? 234 TYR U O 1 ATOM 2649 C CB . TYR B 2 234 ? 39.364 10.742 14.368 1.00 23.74 ? 234 TYR U CB 1 ATOM 2650 C CG . TYR B 2 234 ? 39.984 9.350 14.306 1.00 25.77 ? 234 TYR U CG 1 ATOM 2651 C CD1 . TYR B 2 234 ? 39.206 8.223 14.012 1.00 26.53 ? 234 TYR U CD1 1 ATOM 2652 C CD2 . TYR B 2 234 ? 41.362 9.167 14.533 1.00 27.86 ? 234 TYR U CD2 1 ATOM 2653 C CE1 . TYR B 2 234 ? 39.783 6.951 13.958 1.00 28.19 ? 234 TYR U CE1 1 ATOM 2654 C CE2 . TYR B 2 234 ? 41.949 7.907 14.474 1.00 28.95 ? 234 TYR U CE2 1 ATOM 2655 C CZ . TYR B 2 234 ? 41.160 6.806 14.185 1.00 29.47 ? 234 TYR U CZ 1 ATOM 2656 O OH . TYR B 2 234 ? 41.762 5.569 14.125 1.00 30.80 ? 234 TYR U OH 1 ATOM 2657 N N . THR B 2 235 ? 41.106 10.727 11.657 1.00 22.72 ? 235 THR U N 1 ATOM 2658 C CA . THR B 2 235 ? 41.362 10.481 10.227 1.00 22.54 ? 235 THR U CA 1 ATOM 2659 C C . THR B 2 235 ? 41.859 9.056 9.932 1.00 22.60 ? 235 THR U C 1 ATOM 2660 O O . THR B 2 235 ? 42.608 8.478 10.718 1.00 22.67 ? 235 THR U O 1 ATOM 2661 C CB . THR B 2 235 ? 42.360 11.513 9.626 1.00 22.40 ? 235 THR U CB 1 ATOM 2662 O OG1 . THR B 2 235 ? 43.037 10.916 8.518 1.00 21.51 ? 235 THR U OG1 1 ATOM 2663 C CG2 . THR B 2 235 ? 43.405 11.977 10.669 1.00 22.19 ? 235 THR U CG2 1 ATOM 2664 N N . VAL B 2 236 ? 41.448 8.511 8.787 1.00 22.63 ? 236 VAL U N 1 ATOM 2665 C CA . VAL B 2 236 ? 41.711 7.108 8.429 1.00 22.79 ? 236 VAL U CA 1 ATOM 2666 C C . VAL B 2 236 ? 41.764 6.855 6.916 1.00 22.96 ? 236 VAL U C 1 ATOM 2667 O O . VAL B 2 236 ? 40.905 7.321 6.158 1.00 23.04 ? 236 VAL U O 1 ATOM 2668 C CB . VAL B 2 236 ? 40.655 6.163 9.061 1.00 22.76 ? 236 VAL U CB 1 ATOM 2669 C CG1 . VAL B 2 236 ? 40.496 4.855 8.263 1.00 22.12 ? 236 VAL U CG1 1 ATOM 2670 C CG2 . VAL B 2 236 ? 41.002 5.876 10.514 1.00 23.26 ? 236 VAL U CG2 1 ATOM 2671 N N . ARG B 2 237 ? 42.765 6.095 6.485 1.00 22.98 ? 237 ARG U N 1 ATOM 2672 C CA . ARG B 2 237 ? 42.909 5.778 5.075 1.00 23.06 ? 237 ARG U CA 1 ATOM 2673 C C . ARG B 2 237 ? 43.056 4.289 4.766 1.00 23.10 ? 237 ARG U C 1 ATOM 2674 O O . ARG B 2 237 ? 43.456 3.492 5.615 1.00 22.78 ? 237 ARG U O 1 ATOM 2675 C CB . ARG B 2 237 ? 44.056 6.586 4.444 1.00 23.17 ? 237 ARG U CB 1 ATOM 2676 C CG . ARG B 2 237 ? 45.454 6.329 4.999 1.00 23.08 ? 237 ARG U CG 1 ATOM 2677 C CD . ARG B 2 237 ? 46.384 7.448 4.567 1.00 23.05 ? 237 ARG U CD 1 ATOM 2678 N NE . ARG B 2 237 ? 45.796 8.749 4.879 1.00 23.08 ? 237 ARG U NE 1 ATOM 2679 C CZ . ARG B 2 237 ? 45.923 9.842 4.136 1.00 22.69 ? 237 ARG U CZ 1 ATOM 2680 N NH1 . ARG B 2 237 ? 46.622 9.818 3.014 1.00 22.75 ? 237 ARG U NH1 1 ATOM 2681 N NH2 . ARG B 2 237 ? 45.338 10.964 4.520 1.00 22.38 ? 237 ARG U NH2 1 ATOM 2682 N N . GLY B 2 238 ? 42.738 3.929 3.528 1.00 23.35 ? 238 GLY U N 1 ATOM 2683 C CA . GLY B 2 238 ? 42.852 2.556 3.101 1.00 23.55 ? 238 GLY U CA 1 ATOM 2684 C C . GLY B 2 238 ? 42.003 2.154 1.919 1.00 23.72 ? 238 GLY U C 1 ATOM 2685 O O . GLY B 2 238 ? 41.584 2.982 1.112 1.00 23.28 ? 238 GLY U O 1 ATOM 2686 N N . CYS B 2 239 ? 41.721 0.855 1.888 1.00 24.14 ? 239 CYS U N 1 ATOM 2687 C CA . CYS B 2 239 ? 41.311 0.120 0.708 1.00 24.46 ? 239 CYS U CA 1 ATOM 2688 C C . CYS B 2 239 ? 39.847 -0.270 0.810 1.00 24.26 ? 239 CYS U C 1 ATOM 2689 O O . CYS B 2 239 ? 39.434 -0.898 1.783 1.00 24.18 ? 239 CYS U O 1 ATOM 2690 C CB . CYS B 2 239 ? 42.179 -1.125 0.622 1.00 24.58 ? 239 CYS U CB 1 ATOM 2691 S SG . CYS B 2 239 ? 42.222 -1.875 -0.959 1.00 26.70 ? 239 CYS U SG 1 ATOM 2692 N N . ALA B 2 240 ? 39.062 0.113 -0.189 1.00 24.22 ? 240 ALA U N 1 ATOM 2693 C CA . ALA B 2 240 ? 37.608 0.043 -0.076 1.00 24.30 ? 240 ALA U CA 1 ATOM 2694 C C . ALA B 2 240 ? 36.938 -0.314 -1.389 1.00 24.41 ? 240 ALA U C 1 ATOM 2695 O O . ALA B 2 240 ? 37.605 -0.468 -2.415 1.00 24.42 ? 240 ALA U O 1 ATOM 2696 C CB . ALA B 2 240 ? 37.068 1.366 0.428 1.00 24.34 ? 240 ALA U CB 1 ATOM 2697 N N . THR B 2 241 ? 35.612 -0.442 -1.352 1.00 24.27 ? 241 THR U N 1 ATOM 2698 C CA . THR B 2 241 ? 34.837 -0.640 -2.574 1.00 24.10 ? 241 THR U CA 1 ATOM 2699 C C . THR B 2 241 ? 34.510 0.690 -3.276 1.00 24.42 ? 241 THR U C 1 ATOM 2700 O O . THR B 2 241 ? 35.202 1.695 -3.084 1.00 24.48 ? 241 THR U O 1 ATOM 2701 C CB . THR B 2 241 ? 33.526 -1.342 -2.284 1.00 23.80 ? 241 THR U CB 1 ATOM 2702 O OG1 . THR B 2 241 ? 32.593 -0.394 -1.770 1.00 22.67 ? 241 THR U OG1 1 ATOM 2703 C CG2 . THR B 2 241 ? 33.733 -2.425 -1.297 1.00 23.28 ? 241 THR U CG2 1 ATOM 2704 N N . ALA B 2 242 ? 33.459 0.673 -4.099 1.00 24.44 ? 242 ALA U N 1 ATOM 2705 C CA . ALA B 2 242 ? 32.863 1.891 -4.642 1.00 24.37 ? 242 ALA U CA 1 ATOM 2706 C C . ALA B 2 242 ? 31.470 2.075 -4.043 1.00 24.45 ? 242 ALA U C 1 ATOM 2707 O O . ALA B 2 242 ? 30.870 3.143 -4.143 1.00 24.52 ? 242 ALA U O 1 ATOM 2708 C CB . ALA B 2 242 ? 32.797 1.837 -6.159 1.00 24.21 ? 242 ALA U CB 1 ATOM 2709 N N . SER B 2 243 ? 30.953 1.029 -3.418 1.00 24.42 ? 243 SER U N 1 ATOM 2710 C CA . SER B 2 243 ? 29.678 1.136 -2.742 1.00 24.80 ? 243 SER U CA 1 ATOM 2711 C C . SER B 2 243 ? 29.909 1.646 -1.329 1.00 25.13 ? 243 SER U C 1 ATOM 2712 O O . SER B 2 243 ? 29.045 2.319 -0.754 1.00 25.54 ? 243 SER U O 1 ATOM 2713 C CB . SER B 2 243 ? 29.001 -0.220 -2.687 1.00 24.71 ? 243 SER U CB 1 ATOM 2714 O OG . SER B 2 243 ? 29.938 -1.198 -2.284 1.00 24.99 ? 243 SER U OG 1 ATOM 2715 N N . TRP B 2 244 ? 31.078 1.310 -0.778 1.00 25.11 ? 244 TRP U N 1 ATOM 2716 C CA . TRP B 2 244 ? 31.443 1.647 0.599 1.00 24.60 ? 244 TRP U CA 1 ATOM 2717 C C . TRP B 2 244 ? 31.742 3.093 0.592 1.00 24.51 ? 244 TRP U C 1 ATOM 2718 O O . TRP B 2 244 ? 31.233 3.866 1.401 1.00 24.69 ? 244 TRP U O 1 ATOM 2719 C CB . TRP B 2 244 ? 32.715 0.915 1.019 1.00 24.58 ? 244 TRP U CB 1 ATOM 2720 C CG . TRP B 2 244 ? 33.153 1.216 2.411 1.00 23.08 ? 244 TRP U CG 1 ATOM 2721 C CD1 . TRP B 2 244 ? 34.146 2.050 2.783 1.00 21.91 ? 244 TRP U CD1 1 ATOM 2722 C CD2 . TRP B 2 244 ? 32.613 0.667 3.611 1.00 22.29 ? 244 TRP U CD2 1 ATOM 2723 N NE1 . TRP B 2 244 ? 34.268 2.056 4.143 1.00 22.07 ? 244 TRP U NE1 1 ATOM 2724 C CE2 . TRP B 2 244 ? 33.331 1.218 4.675 1.00 21.95 ? 244 TRP U CE2 1 ATOM 2725 C CE3 . TRP B 2 244 ? 31.585 -0.240 3.888 1.00 23.26 ? 244 TRP U CE3 1 ATOM 2726 C CZ2 . TRP B 2 244 ? 33.054 0.910 5.997 1.00 23.38 ? 244 TRP U CZ2 1 ATOM 2727 C CZ3 . TRP B 2 244 ? 31.312 -0.558 5.206 1.00 22.89 ? 244 TRP U CZ3 1 ATOM 2728 C CH2 . TRP B 2 244 ? 32.041 0.017 6.244 1.00 23.58 ? 244 TRP U CH2 1 ATOM 2729 N N . CYS B 2 245 ? 32.586 3.430 -0.364 1.00 24.51 ? 245 CYS U N 1 ATOM 2730 C CA . CYS B 2 245 ? 33.033 4.762 -0.568 1.00 24.97 ? 245 CYS U CA 1 ATOM 2731 C C . CYS B 2 245 ? 31.865 5.659 -0.899 1.00 24.85 ? 245 CYS U C 1 ATOM 2732 O O . CYS B 2 245 ? 32.005 6.868 -0.943 1.00 24.72 ? 245 CYS U O 1 ATOM 2733 C CB . CYS B 2 245 ? 34.009 4.758 -1.704 1.00 25.08 ? 245 CYS U CB 1 ATOM 2734 S SG . CYS B 2 245 ? 34.887 6.243 -1.760 1.00 27.86 ? 245 CYS U SG 1 ATOM 2735 N N . GLN B 2 246 ? 30.702 5.057 -1.102 1.00 25.07 ? 246 GLN U N 1 ATOM 2736 C CA . GLN B 2 246 ? 29.513 5.808 -1.421 1.00 25.40 ? 246 GLN U CA 1 ATOM 2737 C C . GLN B 2 246 ? 28.422 5.559 -0.386 1.00 25.38 ? 246 GLN U C 1 ATOM 2738 O O . GLN B 2 246 ? 28.321 4.476 0.192 1.00 24.95 ? 246 GLN U O 1 ATOM 2739 C CB . GLN B 2 246 ? 29.038 5.418 -2.815 1.00 25.70 ? 246 GLN U CB 1 ATOM 2740 C CG . GLN B 2 246 ? 27.997 6.339 -3.423 1.00 26.94 ? 246 GLN U CG 1 ATOM 2741 C CD . GLN B 2 246 ? 27.203 5.661 -4.532 1.00 28.26 ? 246 GLN U CD 1 ATOM 2742 O OE1 . GLN B 2 246 ? 27.182 4.425 -4.646 1.00 28.20 ? 246 GLN U OE1 1 ATOM 2743 N NE2 . GLN B 2 246 ? 26.539 6.469 -5.356 1.00 28.99 ? 246 GLN U NE2 1 ATOM 2744 N N . GLY B 2 247 ? 27.609 6.582 -0.155 1.00 25.63 ? 247 GLY U N 1 ATOM 2745 C CA . GLY B 2 247 ? 26.491 6.485 0.772 1.00 25.75 ? 247 GLY U CA 1 ATOM 2746 C C . GLY B 2 247 ? 26.869 6.599 2.237 1.00 25.83 ? 247 GLY U C 1 ATOM 2747 O O . GLY B 2 247 ? 27.956 7.079 2.605 1.00 25.92 ? 247 GLY U O 1 ATOM 2748 N N . SER B 2 248 ? 25.957 6.121 3.070 1.00 25.82 ? 248 SER U N 1 ATOM 2749 C CA . SER B 2 248 ? 26.028 6.302 4.513 1.00 25.74 ? 248 SER U CA 1 ATOM 2750 C C . SER B 2 248 ? 27.208 5.622 5.212 1.00 25.50 ? 248 SER U C 1 ATOM 2751 O O . SER B 2 248 ? 27.636 6.077 6.265 1.00 25.17 ? 248 SER U O 1 ATOM 2752 C CB . SER B 2 248 ? 24.728 5.816 5.136 1.00 25.68 ? 248 SER U CB 1 ATOM 2753 O OG . SER B 2 248 ? 24.398 6.630 6.238 1.00 26.20 ? 248 SER U OG 1 ATOM 2754 N N . HIS B 2 249 ? 27.724 4.548 4.609 1.00 25.46 ? 249 HIS U N 1 ATOM 2755 C CA . HIS B 2 249 ? 28.700 3.631 5.236 1.00 25.10 ? 249 HIS U CA 1 ATOM 2756 C C . HIS B 2 249 ? 29.858 4.300 5.933 1.00 24.74 ? 249 HIS U C 1 ATOM 2757 O O . HIS B 2 249 ? 29.764 4.691 7.078 1.00 24.41 ? 249 HIS U O 1 ATOM 2758 C CB . HIS B 2 249 ? 29.261 2.650 4.203 1.00 25.10 ? 249 HIS U CB 1 ATOM 2759 C CG . HIS B 2 249 ? 28.213 1.853 3.502 1.00 24.87 ? 249 HIS U CG 1 ATOM 2760 N ND1 . HIS B 2 249 ? 27.834 2.108 2.203 1.00 25.79 ? 249 HIS U ND1 1 ATOM 2761 C CD2 . HIS B 2 249 ? 27.451 0.819 3.923 1.00 24.39 ? 249 HIS U CD2 1 ATOM 2762 C CE1 . HIS B 2 249 ? 26.892 1.254 1.846 1.00 25.67 ? 249 HIS U CE1 1 ATOM 2763 N NE2 . HIS B 2 249 ? 26.637 0.466 2.875 1.00 25.56 ? 249 HIS U NE2 1 ATOM 2764 N N . VAL B 2 250 ? 30.969 4.395 5.227 1.00 24.73 ? 250 VAL U N 1 ATOM 2765 C CA . VAL B 2 250 ? 32.107 5.181 5.669 1.00 24.68 ? 250 VAL U CA 1 ATOM 2766 C C . VAL B 2 250 ? 31.798 6.070 6.880 1.00 24.64 ? 250 VAL U C 1 ATOM 2767 O O . VAL B 2 250 ? 32.430 5.940 7.911 1.00 24.55 ? 250 VAL U O 1 ATOM 2768 C CB . VAL B 2 250 ? 32.647 6.018 4.495 1.00 24.59 ? 250 VAL U CB 1 ATOM 2769 C CG1 . VAL B 2 250 ? 31.470 6.601 3.649 1.00 24.52 ? 250 VAL U CG1 1 ATOM 2770 C CG2 . VAL B 2 250 ? 33.621 7.068 4.989 1.00 23.72 ? 250 VAL U CG2 1 ATOM 2771 N N . ALA B 2 251 ? 30.813 6.951 6.752 1.00 24.93 ? 251 ALA U N 1 ATOM 2772 C CA . ALA B 2 251 ? 30.429 7.855 7.836 1.00 25.27 ? 251 ALA U CA 1 ATOM 2773 C C . ALA B 2 251 ? 30.374 7.148 9.174 1.00 25.37 ? 251 ALA U C 1 ATOM 2774 O O . ALA B 2 251 ? 31.101 7.499 10.098 1.00 25.73 ? 251 ALA U O 1 ATOM 2775 C CB . ALA B 2 251 ? 29.089 8.515 7.544 1.00 25.41 ? 251 ALA U CB 1 ATOM 2776 N N . ASP B 2 252 ? 29.518 6.143 9.270 1.00 25.39 ? 252 ASP U N 1 ATOM 2777 C CA . ASP B 2 252 ? 29.356 5.410 10.503 1.00 25.36 ? 252 ASP U CA 1 ATOM 2778 C C . ASP B 2 252 ? 30.533 4.476 10.768 1.00 24.81 ? 252 ASP U C 1 ATOM 2779 O O . ASP B 2 252 ? 30.598 3.865 11.819 1.00 25.17 ? 252 ASP U O 1 ATOM 2780 C CB . ASP B 2 252 ? 28.032 4.647 10.494 1.00 25.74 ? 252 ASP U CB 1 ATOM 2781 C CG . ASP B 2 252 ? 28.048 3.429 9.557 1.00 28.09 ? 252 ASP U CG 1 ATOM 2782 O OD1 . ASP B 2 252 ? 27.291 2.464 9.824 1.00 30.94 ? 252 ASP U OD1 1 ATOM 2783 O OD2 . ASP B 2 252 ? 28.812 3.412 8.562 1.00 29.95 ? 252 ASP U OD2 1 ATOM 2784 N N . SER B 2 253 ? 31.463 4.375 9.829 1.00 24.29 ? 253 SER U N 1 ATOM 2785 C CA . SER B 2 253 ? 32.612 3.509 9.993 1.00 24.28 ? 253 SER U CA 1 ATOM 2786 C C . SER B 2 253 ? 33.340 3.826 11.296 1.00 24.39 ? 253 SER U C 1 ATOM 2787 O O . SER B 2 253 ? 34.176 3.045 11.755 1.00 24.23 ? 253 SER U O 1 ATOM 2788 C CB . SER B 2 253 ? 33.536 3.642 8.773 1.00 24.52 ? 253 SER U CB 1 ATOM 2789 O OG . SER B 2 253 ? 34.816 3.051 8.951 1.00 24.93 ? 253 SER U OG 1 ATOM 2790 N N . PHE B 2 254 ? 33.002 4.966 11.898 1.00 24.85 ? 254 PHE U N 1 ATOM 2791 C CA . PHE B 2 254 ? 33.589 5.399 13.179 1.00 25.64 ? 254 PHE U CA 1 ATOM 2792 C C . PHE B 2 254 ? 32.611 6.202 14.062 1.00 26.58 ? 254 PHE U C 1 ATOM 2793 O O . PHE B 2 254 ? 31.770 6.913 13.514 1.00 26.99 ? 254 PHE U O 1 ATOM 2794 C CB . PHE B 2 254 ? 34.873 6.207 12.932 1.00 25.45 ? 254 PHE U CB 1 ATOM 2795 C CG . PHE B 2 254 ? 34.811 7.149 11.742 1.00 24.18 ? 254 PHE U CG 1 ATOM 2796 C CD1 . PHE B 2 254 ? 33.943 8.234 11.724 1.00 22.79 ? 254 PHE U CD1 1 ATOM 2797 C CD2 . PHE B 2 254 ? 35.664 6.968 10.661 1.00 22.65 ? 254 PHE U CD2 1 ATOM 2798 C CE1 . PHE B 2 254 ? 33.912 9.100 10.644 1.00 21.54 ? 254 PHE U CE1 1 ATOM 2799 C CE2 . PHE B 2 254 ? 35.631 7.829 9.589 1.00 21.30 ? 254 PHE U CE2 1 ATOM 2800 C CZ . PHE B 2 254 ? 34.757 8.899 9.584 1.00 21.03 ? 254 PHE U CZ 1 ATOM 2801 N N . PRO B 2 255 ? 32.746 6.132 15.418 1.00 27.28 ? 255 PRO U N 1 ATOM 2802 C CA . PRO B 2 255 ? 31.812 6.746 16.397 1.00 28.02 ? 255 PRO U CA 1 ATOM 2803 C C . PRO B 2 255 ? 30.847 7.820 15.831 1.00 28.96 ? 255 PRO U C 1 ATOM 2804 O O . PRO B 2 255 ? 29.745 7.466 15.381 1.00 29.02 ? 255 PRO U O 1 ATOM 2805 C CB . PRO B 2 255 ? 32.756 7.352 17.446 1.00 27.78 ? 255 PRO U CB 1 ATOM 2806 C CG . PRO B 2 255 ? 34.138 6.763 17.140 1.00 27.38 ? 255 PRO U CG 1 ATOM 2807 C CD . PRO B 2 255 ? 33.974 5.702 16.103 1.00 26.99 ? 255 PRO U CD 1 ATOM 2808 N N . THR B 2 256 ? 31.249 9.098 15.863 1.00 29.81 ? 256 THR U N 1 ATOM 2809 C CA . THR B 2 256 ? 30.523 10.185 15.176 1.00 30.58 ? 256 THR U CA 1 ATOM 2810 C C . THR B 2 256 ? 31.508 11.139 14.522 1.00 31.63 ? 256 THR U C 1 ATOM 2811 O O . THR B 2 256 ? 32.681 11.138 14.881 1.00 31.73 ? 256 THR U O 1 ATOM 2812 C CB . THR B 2 256 ? 29.692 11.044 16.144 1.00 30.26 ? 256 THR U CB 1 ATOM 2813 O OG1 . THR B 2 256 ? 29.161 10.219 17.185 1.00 30.30 ? 256 THR U OG1 1 ATOM 2814 C CG2 . THR B 2 256 ? 28.556 11.771 15.400 1.00 29.18 ? 256 THR U CG2 1 ATOM 2815 N N . HIS B 2 257 ? 31.029 11.937 13.562 1.00 32.84 ? 257 HIS U N 1 ATOM 2816 C CA . HIS B 2 257 ? 31.738 13.137 13.099 1.00 33.94 ? 257 HIS U CA 1 ATOM 2817 C C . HIS B 2 257 ? 31.060 13.986 12.025 1.00 34.85 ? 257 HIS U C 1 ATOM 2818 O O . HIS B 2 257 ? 29.878 13.807 11.746 1.00 34.89 ? 257 HIS U O 1 ATOM 2819 C CB . HIS B 2 257 ? 33.178 12.843 12.712 1.00 33.98 ? 257 HIS U CB 1 ATOM 2820 C CG . HIS B 2 257 ? 34.159 13.273 13.748 1.00 34.77 ? 257 HIS U CG 1 ATOM 2821 N ND1 . HIS B 2 257 ? 35.112 12.429 14.269 1.00 35.96 ? 257 HIS U ND1 1 ATOM 2822 C CD2 . HIS B 2 257 ? 34.308 14.454 14.392 1.00 35.78 ? 257 HIS U CD2 1 ATOM 2823 C CE1 . HIS B 2 257 ? 35.827 13.080 15.172 1.00 36.74 ? 257 HIS U CE1 1 ATOM 2824 N NE2 . HIS B 2 257 ? 35.359 14.312 15.265 1.00 36.28 ? 257 HIS U NE2 1 ATOM 2825 N N . LEU B 2 258 ? 31.857 14.879 11.425 1.00 36.25 ? 258 LEU U N 1 ATOM 2826 C CA . LEU B 2 258 ? 31.431 16.048 10.627 1.00 37.41 ? 258 LEU U CA 1 ATOM 2827 C C . LEU B 2 258 ? 30.582 15.744 9.390 1.00 38.18 ? 258 LEU U C 1 ATOM 2828 O O . LEU B 2 258 ? 29.611 14.992 9.442 1.00 38.25 ? 258 LEU U O 1 ATOM 2829 C CB . LEU B 2 258 ? 32.687 16.818 10.181 1.00 37.39 ? 258 LEU U CB 1 ATOM 2830 C CG . LEU B 2 258 ? 32.863 18.334 10.383 1.00 37.86 ? 258 LEU U CG 1 ATOM 2831 C CD1 . LEU B 2 258 ? 34.053 18.838 9.550 1.00 37.30 ? 258 LEU U CD1 1 ATOM 2832 C CD2 . LEU B 2 258 ? 31.600 19.157 10.088 1.00 37.87 ? 258 LEU U CD2 1 ATOM 2833 N N . ASN B 2 259 ? 30.939 16.379 8.281 1.00 39.31 ? 259 ASN U N 1 ATOM 2834 C CA . ASN B 2 259 ? 30.463 15.977 6.962 1.00 40.54 ? 259 ASN U CA 1 ATOM 2835 C C . ASN B 2 259 ? 31.368 14.828 6.504 1.00 39.51 ? 259 ASN U C 1 ATOM 2836 O O . ASN B 2 259 ? 31.233 14.293 5.391 1.00 39.48 ? 259 ASN U O 1 ATOM 2837 C CB . ASN B 2 259 ? 30.540 17.158 5.981 1.00 41.75 ? 259 ASN U CB 1 ATOM 2838 C CG . ASN B 2 259 ? 30.436 18.513 6.677 1.00 47.06 ? 259 ASN U CG 1 ATOM 2839 O OD1 . ASN B 2 259 ? 29.521 18.753 7.474 1.00 47.41 ? 259 ASN U OD1 1 ATOM 2840 N ND2 . ASN B 2 259 ? 31.384 19.404 6.374 1.00 56.64 ? 259 ASN U ND2 1 ATOM 2841 N N . VAL B 2 260 ? 32.286 14.464 7.404 1.00 38.26 ? 260 VAL U N 1 ATOM 2842 C CA . VAL B 2 260 ? 33.322 13.453 7.194 1.00 36.94 ? 260 VAL U CA 1 ATOM 2843 C C . VAL B 2 260 ? 33.859 13.357 5.763 1.00 36.03 ? 260 VAL U C 1 ATOM 2844 O O . VAL B 2 260 ? 33.794 12.301 5.142 1.00 35.85 ? 260 VAL U O 1 ATOM 2845 C CB . VAL B 2 260 ? 32.890 12.072 7.717 1.00 36.90 ? 260 VAL U CB 1 ATOM 2846 C CG1 . VAL B 2 260 ? 32.552 12.158 9.191 1.00 36.70 ? 260 VAL U CG1 1 ATOM 2847 C CG2 . VAL B 2 260 ? 31.712 11.533 6.921 1.00 37.22 ? 260 VAL U CG2 1 ATOM 2848 N N . SER B 2 261 ? 34.399 14.461 5.253 1.00 34.84 ? 261 SER U N 1 ATOM 2849 C CA . SER B 2 261 ? 34.984 14.462 3.929 1.00 33.82 ? 261 SER U CA 1 ATOM 2850 C C . SER B 2 261 ? 35.707 13.143 3.699 1.00 33.10 ? 261 SER U C 1 ATOM 2851 O O . SER B 2 261 ? 36.480 12.674 4.544 1.00 32.84 ? 261 SER U O 1 ATOM 2852 C CB . SER B 2 261 ? 35.962 15.613 3.765 1.00 34.02 ? 261 SER U CB 1 ATOM 2853 O OG . SER B 2 261 ? 37.297 15.155 3.897 1.00 34.41 ? 261 SER U OG 1 ATOM 2854 N N . VAL B 2 262 ? 35.446 12.565 2.536 1.00 32.32 ? 262 VAL U N 1 ATOM 2855 C CA . VAL B 2 262 ? 35.889 11.224 2.202 1.00 31.59 ? 262 VAL U CA 1 ATOM 2856 C C . VAL B 2 262 ? 36.345 11.206 0.732 1.00 31.27 ? 262 VAL U C 1 ATOM 2857 O O . VAL B 2 262 ? 35.746 11.893 -0.092 1.00 31.17 ? 262 VAL U O 1 ATOM 2858 C CB . VAL B 2 262 ? 34.736 10.214 2.514 1.00 31.38 ? 262 VAL U CB 1 ATOM 2859 C CG1 . VAL B 2 262 ? 33.390 10.770 2.074 1.00 30.67 ? 262 VAL U CG1 1 ATOM 2860 C CG2 . VAL B 2 262 ? 34.997 8.835 1.923 1.00 31.44 ? 262 VAL U CG2 1 ATOM 2861 N N . SER B 2 263 ? 37.406 10.462 0.407 1.00 30.91 ? 263 SER U N 1 ATOM 2862 C CA . SER B 2 263 ? 37.882 10.410 -0.988 1.00 30.97 ? 263 SER U CA 1 ATOM 2863 C C . SER B 2 263 ? 38.332 9.064 -1.577 1.00 30.77 ? 263 SER U C 1 ATOM 2864 O O . SER B 2 263 ? 38.956 8.254 -0.900 1.00 30.47 ? 263 SER U O 1 ATOM 2865 C CB . SER B 2 263 ? 38.953 11.473 -1.248 1.00 31.02 ? 263 SER U CB 1 ATOM 2866 O OG . SER B 2 263 ? 38.377 12.624 -1.841 1.00 31.31 ? 263 SER U OG 1 ATOM 2867 N N . CYS B 2 264 ? 38.031 8.879 -2.868 1.00 30.67 ? 264 CYS U N 1 ATOM 2868 C CA . CYS B 2 264 ? 38.316 7.647 -3.605 1.00 30.57 ? 264 CYS U CA 1 ATOM 2869 C C . CYS B 2 264 ? 39.001 7.858 -4.941 1.00 30.51 ? 264 CYS U C 1 ATOM 2870 O O . CYS B 2 264 ? 38.688 8.807 -5.660 1.00 30.37 ? 264 CYS U O 1 ATOM 2871 C CB . CYS B 2 264 ? 37.020 6.898 -3.859 1.00 30.33 ? 264 CYS U CB 1 ATOM 2872 S SG . CYS B 2 264 ? 36.679 5.686 -2.576 1.00 31.33 ? 264 CYS U SG 1 ATOM 2873 N N . CYS B 2 265 ? 39.927 6.964 -5.275 1.00 30.57 ? 265 CYS U N 1 ATOM 2874 C CA . CYS B 2 265 ? 40.433 6.900 -6.642 1.00 31.28 ? 265 CYS U CA 1 ATOM 2875 C C . CYS B 2 265 ? 41.153 5.585 -6.968 1.00 31.02 ? 265 CYS U C 1 ATOM 2876 O O . CYS B 2 265 ? 41.475 4.817 -6.057 1.00 31.01 ? 265 CYS U O 1 ATOM 2877 C CB . CYS B 2 265 ? 41.323 8.114 -6.956 1.00 31.58 ? 265 CYS U CB 1 ATOM 2878 S SG . CYS B 2 265 ? 43.089 7.939 -6.559 1.00 33.78 ? 265 CYS U SG 1 ATOM 2879 N N . HIS B 2 266 ? 41.392 5.339 -8.264 1.00 30.76 ? 266 HIS U N 1 ATOM 2880 C CA . HIS B 2 266 ? 42.242 4.225 -8.706 1.00 30.40 ? 266 HIS U CA 1 ATOM 2881 C C . HIS B 2 266 ? 43.738 4.553 -8.556 1.00 30.27 ? 266 HIS U C 1 ATOM 2882 O O . HIS B 2 266 ? 44.158 5.721 -8.641 1.00 30.04 ? 266 HIS U O 1 ATOM 2883 C CB . HIS B 2 266 ? 41.881 3.742 -10.136 1.00 30.42 ? 266 HIS U CB 1 ATOM 2884 C CG . HIS B 2 266 ? 42.821 4.204 -11.227 1.00 30.19 ? 266 HIS U CG 1 ATOM 2885 N ND1 . HIS B 2 266 ? 44.040 3.602 -11.474 1.00 29.54 ? 266 HIS U ND1 1 ATOM 2886 C CD2 . HIS B 2 266 ? 42.686 5.168 -12.173 1.00 29.32 ? 266 HIS U CD2 1 ATOM 2887 C CE1 . HIS B 2 266 ? 44.628 4.196 -12.497 1.00 28.53 ? 266 HIS U CE1 1 ATOM 2888 N NE2 . HIS B 2 266 ? 43.827 5.149 -12.939 1.00 28.61 ? 266 HIS U NE2 1 ATOM 2889 N N . GLY B 2 267 ? 44.526 3.504 -8.323 1.00 30.08 ? 267 GLY U N 1 ATOM 2890 C CA . GLY B 2 267 ? 45.968 3.622 -8.131 1.00 29.71 ? 267 GLY U CA 1 ATOM 2891 C C . GLY B 2 267 ? 46.396 2.989 -6.824 1.00 29.48 ? 267 GLY U C 1 ATOM 2892 O O . GLY B 2 267 ? 45.612 2.915 -5.872 1.00 29.32 ? 267 GLY U O 1 ATOM 2893 N N . SER B 2 268 ? 47.640 2.526 -6.783 1.00 29.28 ? 268 SER U N 1 ATOM 2894 C CA . SER B 2 268 ? 48.216 2.001 -5.556 1.00 29.29 ? 268 SER U CA 1 ATOM 2895 C C . SER B 2 268 ? 48.353 3.119 -4.504 1.00 29.35 ? 268 SER U C 1 ATOM 2896 O O . SER B 2 268 ? 47.708 3.076 -3.449 1.00 29.21 ? 268 SER U O 1 ATOM 2897 C CB . SER B 2 268 ? 49.564 1.332 -5.841 1.00 29.24 ? 268 SER U CB 1 ATOM 2898 O OG . SER B 2 268 ? 49.414 0.240 -6.729 1.00 29.22 ? 268 SER U OG 1 ATOM 2899 N N . GLY B 2 269 ? 49.168 4.129 -4.809 1.00 29.23 ? 269 GLY U N 1 ATOM 2900 C CA . GLY B 2 269 ? 49.394 5.248 -3.895 1.00 28.89 ? 269 GLY U CA 1 ATOM 2901 C C . GLY B 2 269 ? 48.329 6.319 -3.980 1.00 28.74 ? 269 GLY U C 1 ATOM 2902 O O . GLY B 2 269 ? 48.554 7.441 -3.558 1.00 28.56 ? 269 GLY U O 1 ATOM 2903 N N . CYS B 2 270 ? 47.174 5.960 -4.533 1.00 28.94 ? 270 CYS U N 1 ATOM 2904 C CA . CYS B 2 270 ? 46.014 6.841 -4.658 1.00 29.42 ? 270 CYS U CA 1 ATOM 2905 C C . CYS B 2 270 ? 45.738 7.648 -3.388 1.00 29.50 ? 270 CYS U C 1 ATOM 2906 O O . CYS B 2 270 ? 45.432 8.842 -3.463 1.00 29.47 ? 270 CYS U O 1 ATOM 2907 C CB . CYS B 2 270 ? 44.770 6.001 -5.006 1.00 29.80 ? 270 CYS U CB 1 ATOM 2908 S SG . CYS B 2 270 ? 43.116 6.822 -4.849 1.00 30.67 ? 270 CYS U SG 1 ATOM 2909 N N . ASN B 2 271 ? 45.844 6.981 -2.232 1.00 29.54 ? 271 ASN U N 1 ATOM 2910 C CA . ASN B 2 271 ? 45.458 7.553 -0.934 1.00 29.30 ? 271 ASN U CA 1 ATOM 2911 C C . ASN B 2 271 ? 46.609 7.956 0.005 1.00 29.46 ? 271 ASN U C 1 ATOM 2912 O O . ASN B 2 271 ? 46.374 8.303 1.163 1.00 29.63 ? 271 ASN U O 1 ATOM 2913 C CB . ASN B 2 271 ? 44.436 6.647 -0.217 1.00 29.02 ? 271 ASN U CB 1 ATOM 2914 C CG . ASN B 2 271 ? 45.055 5.384 0.382 1.00 28.30 ? 271 ASN U CG 1 ATOM 2915 O OD1 . ASN B 2 271 ? 44.513 4.824 1.338 1.00 27.50 ? 271 ASN U OD1 1 ATOM 2916 N ND2 . ASN B 2 271 ? 46.173 4.927 -0.177 1.00 26.73 ? 271 ASN U ND2 1 ATOM 2917 N N . SER B 2 272 ? 47.841 7.911 -0.497 1.00 29.56 ? 272 SER U N 1 ATOM 2918 C CA . SER B 2 272 ? 48.983 8.500 0.197 1.00 29.61 ? 272 SER U CA 1 ATOM 2919 C C . SER B 2 272 ? 48.649 9.951 0.487 1.00 29.67 ? 272 SER U C 1 ATOM 2920 O O . SER B 2 272 ? 47.941 10.566 -0.306 1.00 29.54 ? 272 SER U O 1 ATOM 2921 C CB . SER B 2 272 ? 50.223 8.444 -0.689 1.00 29.58 ? 272 SER U CB 1 ATOM 2922 O OG . SER B 2 272 ? 51.375 8.835 0.034 1.00 29.72 ? 272 SER U OG 1 ATOM 2923 N N . PRO B 2 273 ? 49.136 10.496 1.620 1.00 29.85 ? 273 PRO U N 1 ATOM 2924 C CA . PRO B 2 273 ? 48.899 11.888 2.026 1.00 30.18 ? 273 PRO U CA 1 ATOM 2925 C C . PRO B 2 273 ? 48.850 12.909 0.868 1.00 30.56 ? 273 PRO U C 1 ATOM 2926 O O . PRO B 2 273 ? 49.706 13.801 0.784 1.00 30.60 ? 273 PRO U O 1 ATOM 2927 C CB . PRO B 2 273 ? 50.075 12.160 2.960 1.00 30.19 ? 273 PRO U CB 1 ATOM 2928 C CG . PRO B 2 273 ? 50.318 10.835 3.618 1.00 29.92 ? 273 PRO U CG 1 ATOM 2929 C CD . PRO B 2 273 ? 49.865 9.755 2.667 1.00 29.75 ? 273 PRO U CD 1 ATOM 2930 N N . THR B 2 274 ? 47.812 12.777 0.029 1.00 30.92 ? 274 THR U N 1 ATOM 2931 C CA . THR B 2 274 ? 47.620 13.500 -1.254 1.00 31.20 ? 274 THR U CA 1 ATOM 2932 C C . THR B 2 274 ? 48.866 13.479 -2.160 1.00 31.41 ? 274 THR U C 1 ATOM 2933 O O . THR B 2 274 ? 48.961 12.652 -3.069 1.00 31.64 ? 274 THR U O 1 ATOM 2934 C CB . THR B 2 274 ? 47.022 14.927 -1.063 1.00 31.25 ? 274 THR U CB 1 ATOM 2935 O OG1 . THR B 2 274 ? 45.691 14.812 -0.538 1.00 31.31 ? 274 THR U OG1 1 ATOM 2936 C CG2 . THR B 2 274 ? 46.957 15.687 -2.392 1.00 31.23 ? 274 THR U CG2 1 ATOM 2937 N N . ASP C 1 8 ? 18.505 26.476 42.009 1.00 76.29 ? 8 ASP B N 1 ATOM 2938 C CA . ASP C 1 8 ? 19.556 25.755 42.781 1.00 76.71 ? 8 ASP B CA 1 ATOM 2939 C C . ASP C 1 8 ? 20.429 26.688 43.660 1.00 76.86 ? 8 ASP B C 1 ATOM 2940 O O . ASP C 1 8 ? 19.987 27.106 44.739 1.00 77.18 ? 8 ASP B O 1 ATOM 2941 C CB . ASP C 1 8 ? 20.418 24.890 41.842 1.00 76.76 ? 8 ASP B CB 1 ATOM 2942 C CG . ASP C 1 8 ? 21.240 23.832 42.591 1.00 77.09 ? 8 ASP B CG 1 ATOM 2943 O OD1 . ASP C 1 8 ? 20.656 23.044 43.372 1.00 77.98 ? 8 ASP B OD1 1 ATOM 2944 O OD2 . ASP C 1 8 ? 22.473 23.778 42.391 1.00 76.80 ? 8 ASP B OD2 1 ATOM 2945 N N . GLU C 1 9 ? 21.650 27.010 43.202 1.00 76.61 ? 9 GLU B N 1 ATOM 2946 C CA . GLU C 1 9 ? 22.655 27.737 44.017 1.00 76.00 ? 9 GLU B CA 1 ATOM 2947 C C . GLU C 1 9 ? 23.592 28.637 43.186 1.00 75.08 ? 9 GLU B C 1 ATOM 2948 O O . GLU C 1 9 ? 24.794 28.344 43.020 1.00 75.03 ? 9 GLU B O 1 ATOM 2949 C CB . GLU C 1 9 ? 23.486 26.749 44.849 1.00 76.37 ? 9 GLU B CB 1 ATOM 2950 C CG . GLU C 1 9 ? 24.309 27.396 45.970 1.00 77.61 ? 9 GLU B CG 1 ATOM 2951 C CD . GLU C 1 9 ? 25.593 26.640 46.267 1.00 79.29 ? 9 GLU B CD 1 ATOM 2952 O OE1 . GLU C 1 9 ? 25.818 25.567 45.645 1.00 80.45 ? 9 GLU B OE1 1 ATOM 2953 O OE2 . GLU C 1 9 ? 26.377 27.126 47.119 1.00 79.32 ? 9 GLU B OE2 1 ATOM 2954 N N . SER C 1 10 ? 23.029 29.743 42.692 1.00 73.78 ? 10 SER B N 1 ATOM 2955 C CA . SER C 1 10 ? 23.726 30.683 41.796 1.00 72.07 ? 10 SER B CA 1 ATOM 2956 C C . SER C 1 10 ? 23.507 32.148 42.210 1.00 70.41 ? 10 SER B C 1 ATOM 2957 O O . SER C 1 10 ? 24.413 32.778 42.788 1.00 70.76 ? 10 SER B O 1 ATOM 2958 C CB . SER C 1 10 ? 23.253 30.473 40.358 1.00 72.30 ? 10 SER B CB 1 ATOM 2959 O OG . SER C 1 10 ? 21.835 30.383 40.301 1.00 72.95 ? 10 SER B OG 1 ATOM 2960 N N . ASN C 1 11 ? 22.300 32.658 41.927 1.00 67.42 ? 11 ASN B N 1 ATOM 2961 C CA . ASN C 1 11 ? 21.892 34.056 42.156 1.00 64.68 ? 11 ASN B CA 1 ATOM 2962 C C . ASN C 1 11 ? 21.942 34.881 40.850 1.00 62.69 ? 11 ASN B C 1 ATOM 2963 O O . ASN C 1 11 ? 20.890 35.164 40.245 1.00 62.30 ? 11 ASN B O 1 ATOM 2964 C CB . ASN C 1 11 ? 22.679 34.715 43.316 1.00 64.64 ? 11 ASN B CB 1 ATOM 2965 C CG . ASN C 1 11 ? 22.027 35.984 43.820 1.00 64.15 ? 11 ASN B CG 1 ATOM 2966 O OD1 . ASN C 1 11 ? 21.318 35.972 44.826 1.00 63.56 ? 11 ASN B OD1 1 ATOM 2967 N ND2 . ASN C 1 11 ? 22.253 37.086 43.115 1.00 63.54 ? 11 ASN B ND2 1 ATOM 2968 N N . CYS C 1 12 ? 23.159 35.243 40.426 1.00 59.88 ? 12 CYS B N 1 ATOM 2969 C CA . CYS C 1 12 ? 23.404 35.969 39.171 1.00 57.01 ? 12 CYS B CA 1 ATOM 2970 C C . CYS C 1 12 ? 22.511 35.412 38.113 1.00 55.57 ? 12 CYS B C 1 ATOM 2971 O O . CYS C 1 12 ? 22.467 34.201 37.945 1.00 55.55 ? 12 CYS B O 1 ATOM 2972 C CB . CYS C 1 12 ? 24.853 35.797 38.732 1.00 56.47 ? 12 CYS B CB 1 ATOM 2973 S SG . CYS C 1 12 ? 25.667 34.441 39.622 1.00 54.37 ? 12 CYS B SG 1 ATOM 2974 N N . GLY C 1 13 ? 21.783 36.296 37.435 1.00 53.74 ? 13 GLY B N 1 ATOM 2975 C CA . GLY C 1 13 ? 20.837 35.929 36.373 1.00 51.95 ? 13 GLY B CA 1 ATOM 2976 C C . GLY C 1 13 ? 20.289 34.503 36.371 1.00 50.34 ? 13 GLY B C 1 ATOM 2977 O O . GLY C 1 13 ? 19.138 34.276 36.749 1.00 50.18 ? 13 GLY B O 1 ATOM 2978 N N . CYS C 1 14 ? 21.127 33.563 35.922 1.00 48.50 ? 14 CYS B N 1 ATOM 2979 C CA . CYS C 1 14 ? 20.867 32.121 35.934 1.00 46.60 ? 14 CYS B CA 1 ATOM 2980 C C . CYS C 1 14 ? 19.486 31.771 36.409 1.00 45.74 ? 14 CYS B C 1 ATOM 2981 O O . CYS C 1 14 ? 19.132 32.085 37.547 1.00 45.91 ? 14 CYS B O 1 ATOM 2982 C CB . CYS C 1 14 ? 21.913 31.395 36.783 1.00 46.29 ? 14 CYS B CB 1 ATOM 2983 S SG . CYS C 1 14 ? 23.524 31.158 35.930 1.00 46.16 ? 14 CYS B SG 1 ATOM 2984 N N . GLN C 1 15 ? 18.708 31.125 35.534 1.00 44.55 ? 15 GLN B N 1 ATOM 2985 C CA . GLN C 1 15 ? 17.297 30.812 35.825 1.00 43.03 ? 15 GLN B CA 1 ATOM 2986 C C . GLN C 1 15 ? 16.957 29.323 35.811 1.00 41.72 ? 15 GLN B C 1 ATOM 2987 O O . GLN C 1 15 ? 17.767 28.482 35.417 1.00 41.36 ? 15 GLN B O 1 ATOM 2988 C CB . GLN C 1 15 ? 16.350 31.613 34.919 1.00 43.12 ? 15 GLN B CB 1 ATOM 2989 C CG . GLN C 1 15 ? 16.568 33.140 35.004 1.00 44.11 ? 15 GLN B CG 1 ATOM 2990 C CD . GLN C 1 15 ? 15.413 33.972 34.432 1.00 44.97 ? 15 GLN B CD 1 ATOM 2991 O OE1 . GLN C 1 15 ? 15.604 34.741 33.481 1.00 44.94 ? 15 GLN B OE1 1 ATOM 2992 N NE2 . GLN C 1 15 ? 14.215 33.825 35.013 1.00 44.33 ? 15 GLN B NE2 1 ATOM 2993 N N . ASN C 1 16 ? 15.748 29.020 36.270 1.00 40.48 ? 16 ASN B N 1 ATOM 2994 C CA . ASN C 1 16 ? 15.247 27.656 36.382 1.00 39.44 ? 16 ASN B CA 1 ATOM 2995 C C . ASN C 1 16 ? 16.205 26.765 37.184 1.00 39.21 ? 16 ASN B C 1 ATOM 2996 O O . ASN C 1 16 ? 16.364 26.993 38.389 1.00 39.59 ? 16 ASN B O 1 ATOM 2997 C CB . ASN C 1 16 ? 14.845 27.098 35.010 1.00 38.99 ? 16 ASN B CB 1 ATOM 2998 C CG . ASN C 1 16 ? 13.768 27.962 34.317 1.00 38.24 ? 16 ASN B CG 1 ATOM 2999 O OD1 . ASN C 1 16 ? 12.591 27.937 34.688 1.00 35.92 ? 16 ASN B OD1 1 ATOM 3000 N ND2 . ASN C 1 16 ? 14.181 28.727 33.302 1.00 37.69 ? 16 ASN B ND2 1 ATOM 3001 N N . GLY C 1 17 ? 16.845 25.774 36.561 1.00 38.56 ? 17 GLY B N 1 ATOM 3002 C CA . GLY C 1 17 ? 17.814 24.932 37.285 1.00 37.53 ? 17 GLY B CA 1 ATOM 3003 C C . GLY C 1 17 ? 19.086 25.734 37.411 1.00 36.85 ? 17 GLY B C 1 ATOM 3004 O O . GLY C 1 17 ? 19.065 26.826 37.936 1.00 37.13 ? 17 GLY B O 1 ATOM 3005 N N . GLY C 1 18 ? 20.196 25.192 36.939 1.00 36.29 ? 18 GLY B N 1 ATOM 3006 C CA . GLY C 1 18 ? 21.343 26.005 36.544 1.00 35.89 ? 18 GLY B CA 1 ATOM 3007 C C . GLY C 1 18 ? 22.068 26.888 37.533 1.00 35.59 ? 18 GLY B C 1 ATOM 3008 O O . GLY C 1 18 ? 21.487 27.733 38.190 1.00 35.33 ? 18 GLY B O 1 ATOM 3009 N N . VAL C 1 19 ? 23.373 26.721 37.602 1.00 35.78 ? 19 VAL B N 1 ATOM 3010 C CA . VAL C 1 19 ? 24.132 27.468 38.570 1.00 36.15 ? 19 VAL B CA 1 ATOM 3011 C C . VAL C 1 19 ? 25.292 28.236 37.964 1.00 36.56 ? 19 VAL B C 1 ATOM 3012 O O . VAL C 1 19 ? 25.941 27.807 37.014 1.00 36.09 ? 19 VAL B O 1 ATOM 3013 C CB . VAL C 1 19 ? 24.597 26.583 39.744 1.00 36.18 ? 19 VAL B CB 1 ATOM 3014 C CG1 . VAL C 1 19 ? 23.550 25.515 40.032 1.00 36.28 ? 19 VAL B CG1 1 ATOM 3015 C CG2 . VAL C 1 19 ? 25.956 25.947 39.463 1.00 35.57 ? 19 VAL B CG2 1 ATOM 3016 N N . CYS C 1 20 ? 25.529 29.390 38.566 1.00 37.46 ? 20 CYS B N 1 ATOM 3017 C CA . CYS C 1 20 ? 26.530 30.338 38.150 1.00 38.30 ? 20 CYS B CA 1 ATOM 3018 C C . CYS C 1 20 ? 27.914 29.753 38.319 1.00 36.93 ? 20 CYS B C 1 ATOM 3019 O O . CYS C 1 20 ? 28.157 28.926 39.199 1.00 36.77 ? 20 CYS B O 1 ATOM 3020 C CB . CYS C 1 20 ? 26.410 31.560 39.041 1.00 39.48 ? 20 CYS B CB 1 ATOM 3021 S SG . CYS C 1 20 ? 26.343 33.128 38.185 1.00 46.42 ? 20 CYS B SG 1 ATOM 3022 N N . VAL C 1 21 ? 28.821 30.200 37.467 1.00 35.64 ? 21 VAL B N 1 ATOM 3023 C CA . VAL C 1 21 ? 30.218 29.787 37.522 1.00 34.28 ? 21 VAL B CA 1 ATOM 3024 C C . VAL C 1 21 ? 31.102 30.855 36.853 1.00 33.54 ? 21 VAL B C 1 ATOM 3025 O O . VAL C 1 21 ? 31.091 30.994 35.626 1.00 33.86 ? 21 VAL B O 1 ATOM 3026 C CB . VAL C 1 21 ? 30.413 28.373 36.914 1.00 34.20 ? 21 VAL B CB 1 ATOM 3027 C CG1 . VAL C 1 21 ? 29.229 27.981 36.034 1.00 33.69 ? 21 VAL B CG1 1 ATOM 3028 C CG2 . VAL C 1 21 ? 31.735 28.258 36.167 1.00 34.01 ? 21 VAL B CG2 1 ATOM 3029 N N . SER C 1 22 ? 31.835 31.621 37.668 1.00 32.05 ? 22 SER B N 1 ATOM 3030 C CA . SER C 1 22 ? 32.710 32.701 37.190 1.00 30.54 ? 22 SER B CA 1 ATOM 3031 C C . SER C 1 22 ? 34.117 32.176 36.879 1.00 29.63 ? 22 SER B C 1 ATOM 3032 O O . SER C 1 22 ? 34.415 31.019 37.131 1.00 29.92 ? 22 SER B O 1 ATOM 3033 C CB . SER C 1 22 ? 32.797 33.789 38.247 1.00 30.54 ? 22 SER B CB 1 ATOM 3034 O OG . SER C 1 22 ? 33.405 33.270 39.410 1.00 30.39 ? 22 SER B OG 1 ATOM 3035 N N . TYR C 1 23 ? 34.986 33.004 36.318 1.00 28.17 ? 23 TYR B N 1 ATOM 3036 C CA . TYR C 1 23 ? 36.327 32.544 36.006 1.00 26.96 ? 23 TYR B CA 1 ATOM 3037 C C . TYR C 1 23 ? 37.401 33.548 36.386 1.00 26.31 ? 23 TYR B C 1 ATOM 3038 O O . TYR C 1 23 ? 37.810 34.390 35.601 1.00 25.65 ? 23 TYR B O 1 ATOM 3039 C CB . TYR C 1 23 ? 36.453 32.116 34.548 1.00 27.07 ? 23 TYR B CB 1 ATOM 3040 C CG . TYR C 1 23 ? 35.551 30.983 34.173 1.00 27.09 ? 23 TYR B CG 1 ATOM 3041 C CD1 . TYR C 1 23 ? 36.051 29.712 33.941 1.00 28.03 ? 23 TYR B CD1 1 ATOM 3042 C CD2 . TYR C 1 23 ? 34.189 31.190 34.030 1.00 28.84 ? 23 TYR B CD2 1 ATOM 3043 C CE1 . TYR C 1 23 ? 35.195 28.659 33.601 1.00 30.20 ? 23 TYR B CE1 1 ATOM 3044 C CE2 . TYR C 1 23 ? 33.327 30.163 33.687 1.00 30.69 ? 23 TYR B CE2 1 ATOM 3045 C CZ . TYR C 1 23 ? 33.827 28.902 33.476 1.00 31.19 ? 23 TYR B CZ 1 ATOM 3046 O OH . TYR C 1 23 ? 32.936 27.916 33.129 1.00 32.42 ? 23 TYR B OH 1 ATOM 3047 N N . LYS C 1 24 ? 37.810 33.428 37.642 1.00 26.16 ? 24 LYS B N 1 ATOM 3048 C CA . LYS C 1 24 ? 39.031 34.006 38.220 1.00 25.76 ? 24 LYS B CA 1 ATOM 3049 C C . LYS C 1 24 ? 39.979 34.700 37.224 1.00 25.49 ? 24 LYS B C 1 ATOM 3050 O O . LYS C 1 24 ? 40.133 35.922 37.295 1.00 25.93 ? 24 LYS B O 1 ATOM 3051 C CB . LYS C 1 24 ? 39.770 32.934 39.048 1.00 25.34 ? 24 LYS B CB 1 ATOM 3052 C CG . LYS C 1 24 ? 40.714 33.481 40.071 1.00 24.34 ? 24 LYS B CG 1 ATOM 3053 C CD . LYS C 1 24 ? 41.911 32.574 40.265 1.00 23.82 ? 24 LYS B CD 1 ATOM 3054 C CE . LYS C 1 24 ? 41.523 31.191 40.768 1.00 24.58 ? 24 LYS B CE 1 ATOM 3055 N NZ . LYS C 1 24 ? 42.635 30.449 41.472 1.00 23.54 ? 24 LYS B NZ 1 ATOM 3056 N N . TYR C 1 25 ? 40.573 33.950 36.296 1.00 24.75 ? 25 TYR B N 1 ATOM 3057 C CA . TYR C 1 25 ? 41.586 34.507 35.383 1.00 24.63 ? 25 TYR B CA 1 ATOM 3058 C C . TYR C 1 25 ? 41.111 35.326 34.142 1.00 24.95 ? 25 TYR B C 1 ATOM 3059 O O . TYR C 1 25 ? 41.922 35.725 33.284 1.00 24.76 ? 25 TYR B O 1 ATOM 3060 C CB . TYR C 1 25 ? 42.509 33.396 34.946 1.00 24.19 ? 25 TYR B CB 1 ATOM 3061 C CG . TYR C 1 25 ? 43.347 32.938 36.075 1.00 24.22 ? 25 TYR B CG 1 ATOM 3062 C CD1 . TYR C 1 25 ? 44.530 33.586 36.372 1.00 24.29 ? 25 TYR B CD1 1 ATOM 3063 C CD2 . TYR C 1 25 ? 42.954 31.869 36.878 1.00 25.06 ? 25 TYR B CD2 1 ATOM 3064 C CE1 . TYR C 1 25 ? 45.316 33.183 37.434 1.00 24.22 ? 25 TYR B CE1 1 ATOM 3065 C CE2 . TYR C 1 25 ? 43.741 31.449 37.941 1.00 24.15 ? 25 TYR B CE2 1 ATOM 3066 C CZ . TYR C 1 25 ? 44.920 32.123 38.209 1.00 23.97 ? 25 TYR B CZ 1 ATOM 3067 O OH . TYR C 1 25 ? 45.731 31.750 39.237 1.00 24.78 ? 25 TYR B OH 1 ATOM 3068 N N . PHE C 1 26 ? 39.806 35.581 34.076 1.00 24.97 ? 26 PHE B N 1 ATOM 3069 C CA . PHE C 1 26 ? 39.157 36.061 32.884 1.00 24.74 ? 26 PHE B CA 1 ATOM 3070 C C . PHE C 1 26 ? 38.160 37.122 33.267 1.00 25.66 ? 26 PHE B C 1 ATOM 3071 O O . PHE C 1 26 ? 36.968 36.999 33.039 1.00 26.06 ? 26 PHE B O 1 ATOM 3072 C CB . PHE C 1 26 ? 38.472 34.877 32.214 1.00 24.18 ? 26 PHE B CB 1 ATOM 3073 C CG . PHE C 1 26 ? 39.418 33.987 31.510 1.00 22.43 ? 26 PHE B CG 1 ATOM 3074 C CD1 . PHE C 1 26 ? 40.060 32.978 32.180 1.00 22.62 ? 26 PHE B CD1 1 ATOM 3075 C CD2 . PHE C 1 26 ? 39.699 34.188 30.183 1.00 22.13 ? 26 PHE B CD2 1 ATOM 3076 C CE1 . PHE C 1 26 ? 40.962 32.172 31.547 1.00 23.22 ? 26 PHE B CE1 1 ATOM 3077 C CE2 . PHE C 1 26 ? 40.593 33.402 29.533 1.00 23.43 ? 26 PHE B CE2 1 ATOM 3078 C CZ . PHE C 1 26 ? 41.233 32.384 30.210 1.00 24.54 ? 26 PHE B CZ 1 ATOM 3079 N N . SER C 1 27 ? 38.657 38.161 33.905 1.00 26.79 ? 27 SER B N 1 ATOM 3080 C CA . SER C 1 27 ? 37.801 39.215 34.439 1.00 27.74 ? 27 SER B CA 1 ATOM 3081 C C . SER C 1 27 ? 36.500 38.693 35.081 1.00 28.37 ? 27 SER B C 1 ATOM 3082 O O . SER C 1 27 ? 35.402 39.142 34.752 1.00 28.41 ? 27 SER B O 1 ATOM 3083 C CB . SER C 1 27 ? 37.541 40.244 33.346 1.00 27.73 ? 27 SER B CB 1 ATOM 3084 O OG . SER C 1 27 ? 38.735 40.462 32.611 1.00 27.57 ? 27 SER B OG 1 ATOM 3085 N N . ARG C 1 28 ? 36.657 37.757 36.022 1.00 29.46 ? 28 ARG B N 1 ATOM 3086 C CA . ARG C 1 28 ? 35.548 37.113 36.756 1.00 30.32 ? 28 ARG B CA 1 ATOM 3087 C C . ARG C 1 28 ? 34.277 36.981 35.900 1.00 30.42 ? 28 ARG B C 1 ATOM 3088 O O . ARG C 1 28 ? 33.245 37.569 36.213 1.00 30.61 ? 28 ARG B O 1 ATOM 3089 C CB . ARG C 1 28 ? 35.287 37.780 38.135 1.00 30.04 ? 28 ARG B CB 1 ATOM 3090 C CG . ARG C 1 28 ? 35.717 39.272 38.251 1.00 32.56 ? 28 ARG B CG 1 ATOM 3091 C CD . ARG C 1 28 ? 36.964 39.584 39.141 1.00 36.05 ? 28 ARG B CD 1 ATOM 3092 N NE . ARG C 1 28 ? 37.658 38.377 39.586 1.00 40.94 ? 28 ARG B NE 1 ATOM 3093 C CZ . ARG C 1 28 ? 37.358 37.701 40.704 1.00 43.93 ? 28 ARG B CZ 1 ATOM 3094 N NH1 . ARG C 1 28 ? 36.384 38.125 41.517 1.00 44.27 ? 28 ARG B NH1 1 ATOM 3095 N NH2 . ARG C 1 28 ? 38.030 36.593 41.020 1.00 44.62 ? 28 ARG B NH2 1 ATOM 3096 N N . ILE C 1 29 ? 34.372 36.205 34.816 1.00 30.72 ? 29 ILE B N 1 ATOM 3097 C CA . ILE C 1 29 ? 33.267 36.066 33.846 1.00 31.26 ? 29 ILE B CA 1 ATOM 3098 C C . ILE C 1 29 ? 32.270 34.906 34.115 1.00 32.05 ? 29 ILE B C 1 ATOM 3099 O O . ILE C 1 29 ? 32.609 33.728 34.040 1.00 32.15 ? 29 ILE B O 1 ATOM 3100 C CB . ILE C 1 29 ? 33.776 36.093 32.364 1.00 31.00 ? 29 ILE B CB 1 ATOM 3101 C CG1 . ILE C 1 29 ? 32.591 36.123 31.394 1.00 31.36 ? 29 ILE B CG1 1 ATOM 3102 C CG2 . ILE C 1 29 ? 34.780 34.971 32.074 1.00 29.48 ? 29 ILE B CG2 1 ATOM 3103 C CD1 . ILE C 1 29 ? 32.978 36.323 29.944 1.00 32.23 ? 29 ILE B CD1 1 ATOM 3104 N N . ARG C 1 30 ? 31.029 35.257 34.420 1.00 32.95 ? 30 ARG B N 1 ATOM 3105 C CA . ARG C 1 30 ? 30.042 34.267 34.845 1.00 33.93 ? 30 ARG B CA 1 ATOM 3106 C C . ARG C 1 30 ? 29.574 33.418 33.687 1.00 33.95 ? 30 ARG B C 1 ATOM 3107 O O . ARG C 1 30 ? 29.736 33.787 32.520 1.00 34.21 ? 30 ARG B O 1 ATOM 3108 C CB . ARG C 1 30 ? 28.855 34.939 35.551 1.00 34.36 ? 30 ARG B CB 1 ATOM 3109 C CG . ARG C 1 30 ? 29.097 35.192 37.054 1.00 37.02 ? 30 ARG B CG 1 ATOM 3110 C CD . ARG C 1 30 ? 28.988 36.672 37.457 1.00 40.73 ? 30 ARG B CD 1 ATOM 3111 N NE . ARG C 1 30 ? 27.916 37.356 36.738 1.00 44.25 ? 30 ARG B NE 1 ATOM 3112 C CZ . ARG C 1 30 ? 27.074 38.236 37.278 1.00 47.61 ? 30 ARG B CZ 1 ATOM 3113 N NH1 . ARG C 1 30 ? 27.131 38.558 38.572 1.00 48.72 ? 30 ARG B NH1 1 ATOM 3114 N NH2 . ARG C 1 30 ? 26.148 38.790 36.515 1.00 49.45 ? 30 ARG B NH2 1 ATOM 3115 N N . ARG C 1 31 ? 29.027 32.257 34.032 1.00 34.02 ? 31 ARG B N 1 ATOM 3116 C CA . ARG C 1 31 ? 28.464 31.324 33.075 1.00 33.89 ? 31 ARG B CA 1 ATOM 3117 C C . ARG C 1 31 ? 27.283 30.655 33.733 1.00 33.77 ? 31 ARG B C 1 ATOM 3118 O O . ARG C 1 31 ? 26.902 31.043 34.832 1.00 34.13 ? 31 ARG B O 1 ATOM 3119 C CB . ARG C 1 31 ? 29.490 30.295 32.654 1.00 33.83 ? 31 ARG B CB 1 ATOM 3120 C CG . ARG C 1 31 ? 28.913 29.292 31.720 1.00 34.75 ? 31 ARG B CG 1 ATOM 3121 C CD . ARG C 1 31 ? 29.877 28.202 31.461 1.00 37.13 ? 31 ARG B CD 1 ATOM 3122 N NE . ARG C 1 31 ? 29.231 26.925 31.693 1.00 38.27 ? 31 ARG B NE 1 ATOM 3123 C CZ . ARG C 1 31 ? 29.698 26.011 32.529 1.00 39.79 ? 31 ARG B CZ 1 ATOM 3124 N NH1 . ARG C 1 31 ? 30.824 26.224 33.203 1.00 40.06 ? 31 ARG B NH1 1 ATOM 3125 N NH2 . ARG C 1 31 ? 29.044 24.873 32.678 1.00 41.66 ? 31 ARG B NH2 1 ATOM 3126 N N . CYS C 1 32 ? 26.693 29.662 33.081 1.00 33.67 ? 32 CYS B N 1 ATOM 3127 C CA . CYS C 1 32 ? 25.452 29.129 33.593 1.00 34.23 ? 32 CYS B CA 1 ATOM 3128 C C . CYS C 1 32 ? 25.084 27.698 33.201 1.00 33.55 ? 32 CYS B C 1 ATOM 3129 O O . CYS C 1 32 ? 24.171 27.477 32.405 1.00 34.01 ? 32 CYS B O 1 ATOM 3130 C CB . CYS C 1 32 ? 24.325 30.063 33.225 1.00 34.57 ? 32 CYS B CB 1 ATOM 3131 S SG . CYS C 1 32 ? 23.021 29.870 34.375 1.00 40.40 ? 32 CYS B SG 1 ATOM 3132 N N . SER C 1 33 ? 25.778 26.722 33.777 1.00 32.53 ? 33 SER B N 1 ATOM 3133 C CA . SER C 1 33 ? 25.478 25.310 33.523 1.00 31.21 ? 33 SER B CA 1 ATOM 3134 C C . SER C 1 33 ? 24.028 25.003 33.841 1.00 30.05 ? 33 SER B C 1 ATOM 3135 O O . SER C 1 33 ? 23.652 24.950 35.004 1.00 30.21 ? 33 SER B O 1 ATOM 3136 C CB . SER C 1 33 ? 26.392 24.439 34.355 1.00 31.00 ? 33 SER B CB 1 ATOM 3137 O OG . SER C 1 33 ? 27.062 25.289 35.261 1.00 32.02 ? 33 SER B OG 1 ATOM 3138 N N . CYS C 1 34 ? 23.233 24.805 32.793 1.00 28.32 ? 34 CYS B N 1 ATOM 3139 C CA . CYS C 1 34 ? 21.807 24.640 32.924 1.00 26.81 ? 34 CYS B CA 1 ATOM 3140 C C . CYS C 1 34 ? 21.474 23.189 33.061 1.00 25.04 ? 34 CYS B C 1 ATOM 3141 O O . CYS C 1 34 ? 22.258 22.346 32.656 1.00 24.60 ? 34 CYS B O 1 ATOM 3142 C CB . CYS C 1 34 ? 21.133 25.164 31.669 1.00 27.28 ? 34 CYS B CB 1 ATOM 3143 S SG . CYS C 1 34 ? 21.486 26.897 31.286 1.00 31.04 ? 34 CYS B SG 1 ATOM 3144 N N . PRO C 1 35 ? 20.281 22.887 33.594 1.00 23.79 ? 35 PRO B N 1 ATOM 3145 C CA . PRO C 1 35 ? 19.778 21.547 33.503 1.00 22.92 ? 35 PRO B CA 1 ATOM 3146 C C . PRO C 1 35 ? 19.438 21.300 32.048 1.00 22.49 ? 35 PRO B C 1 ATOM 3147 O O . PRO C 1 35 ? 19.531 22.207 31.235 1.00 22.68 ? 35 PRO B O 1 ATOM 3148 C CB . PRO C 1 35 ? 18.502 21.611 34.337 1.00 22.49 ? 35 PRO B CB 1 ATOM 3149 C CG . PRO C 1 35 ? 18.014 22.932 34.171 1.00 22.44 ? 35 PRO B CG 1 ATOM 3150 C CD . PRO C 1 35 ? 19.246 23.801 34.102 1.00 24.00 ? 35 PRO B CD 1 ATOM 3151 N N . ARG C 1 36 ? 19.016 20.092 31.719 1.00 22.20 ? 36 ARG B N 1 ATOM 3152 C CA . ARG C 1 36 ? 18.741 19.734 30.323 1.00 21.35 ? 36 ARG B CA 1 ATOM 3153 C C . ARG C 1 36 ? 17.652 20.508 29.561 1.00 20.87 ? 36 ARG B C 1 ATOM 3154 O O . ARG C 1 36 ? 17.878 20.869 28.415 1.00 21.12 ? 36 ARG B O 1 ATOM 3155 C CB . ARG C 1 36 ? 18.444 18.246 30.209 1.00 21.34 ? 36 ARG B CB 1 ATOM 3156 C CG . ARG C 1 36 ? 18.703 17.756 28.836 1.00 19.37 ? 36 ARG B CG 1 ATOM 3157 C CD . ARG C 1 36 ? 18.102 16.443 28.601 1.00 16.61 ? 36 ARG B CD 1 ATOM 3158 N NE . ARG C 1 36 ? 18.658 15.965 27.360 1.00 16.40 ? 36 ARG B NE 1 ATOM 3159 C CZ . ARG C 1 36 ? 17.939 15.642 26.304 1.00 16.18 ? 36 ARG B CZ 1 ATOM 3160 N NH1 . ARG C 1 36 ? 16.619 15.702 26.346 1.00 16.01 ? 36 ARG B NH1 1 ATOM 3161 N NH2 . ARG C 1 36 ? 18.553 15.238 25.215 1.00 16.91 ? 36 ARG B NH2 1 ATOM 3162 N N . LYS C 1 37 ? 16.479 20.708 30.158 1.00 20.33 ? 37 LYS B N 1 ATOM 3163 C CA . LYS C 1 37 ? 15.343 21.303 29.442 1.00 20.42 ? 37 LYS B CA 1 ATOM 3164 C C . LYS C 1 37 ? 15.513 22.782 29.184 1.00 20.32 ? 37 LYS B C 1 ATOM 3165 O O . LYS C 1 37 ? 14.644 23.408 28.585 1.00 20.91 ? 37 LYS B O 1 ATOM 3166 C CB . LYS C 1 37 ? 14.011 21.116 30.192 1.00 20.65 ? 37 LYS B CB 1 ATOM 3167 C CG . LYS C 1 37 ? 13.523 19.671 30.290 1.00 22.51 ? 37 LYS B CG 1 ATOM 3168 C CD . LYS C 1 37 ? 12.020 19.548 30.534 1.00 23.47 ? 37 LYS B CD 1 ATOM 3169 C CE . LYS C 1 37 ? 11.587 18.082 30.479 1.00 24.14 ? 37 LYS B CE 1 ATOM 3170 N NZ . LYS C 1 37 ? 10.200 17.877 29.925 1.00 25.06 ? 37 LYS B NZ 1 ATOM 3171 N N . PHE C 1 38 ? 16.602 23.368 29.655 1.00 19.89 ? 38 PHE B N 1 ATOM 3172 C CA . PHE C 1 38 ? 16.743 24.798 29.540 1.00 19.39 ? 38 PHE B CA 1 ATOM 3173 C C . PHE C 1 38 ? 18.101 25.131 29.028 1.00 20.08 ? 38 PHE B C 1 ATOM 3174 O O . PHE C 1 38 ? 19.080 24.526 29.434 1.00 20.25 ? 38 PHE B O 1 ATOM 3175 C CB . PHE C 1 38 ? 16.485 25.477 30.889 1.00 19.05 ? 38 PHE B CB 1 ATOM 3176 C CG . PHE C 1 38 ? 15.163 25.155 31.463 1.00 16.28 ? 38 PHE B CG 1 ATOM 3177 C CD1 . PHE C 1 38 ? 14.031 25.756 30.977 1.00 14.44 ? 38 PHE B CD1 1 ATOM 3178 C CD2 . PHE C 1 38 ? 15.047 24.217 32.467 1.00 15.88 ? 38 PHE B CD2 1 ATOM 3179 C CE1 . PHE C 1 38 ? 12.793 25.436 31.482 1.00 15.31 ? 38 PHE B CE1 1 ATOM 3180 C CE2 . PHE C 1 38 ? 13.814 23.883 32.988 1.00 15.97 ? 38 PHE B CE2 1 ATOM 3181 C CZ . PHE C 1 38 ? 12.680 24.492 32.494 1.00 16.01 ? 38 PHE B CZ 1 ATOM 3182 N N . GLN C 1 39 ? 18.163 26.097 28.131 1.00 21.03 ? 39 GLN B N 1 ATOM 3183 C CA . GLN C 1 39 ? 19.429 26.506 27.566 1.00 22.55 ? 39 GLN B CA 1 ATOM 3184 C C . GLN C 1 39 ? 19.486 28.014 27.620 1.00 23.79 ? 39 GLN B C 1 ATOM 3185 O O . GLN C 1 39 ? 18.607 28.649 28.220 1.00 23.88 ? 39 GLN B O 1 ATOM 3186 C CB . GLN C 1 39 ? 19.562 25.984 26.140 1.00 22.36 ? 39 GLN B CB 1 ATOM 3187 C CG . GLN C 1 39 ? 19.043 24.548 25.997 1.00 23.43 ? 39 GLN B CG 1 ATOM 3188 C CD . GLN C 1 39 ? 18.935 24.060 24.575 1.00 23.81 ? 39 GLN B CD 1 ATOM 3189 O OE1 . GLN C 1 39 ? 19.387 22.968 24.245 1.00 23.75 ? 39 GLN B OE1 1 ATOM 3190 N NE2 . GLN C 1 39 ? 18.323 24.859 23.729 1.00 26.23 ? 39 GLN B NE2 1 ATOM 3191 N N . GLY C 1 40 ? 20.530 28.576 27.015 1.00 25.20 ? 40 GLY B N 1 ATOM 3192 C CA . GLY C 1 40 ? 20.744 30.016 27.000 1.00 27.10 ? 40 GLY B CA 1 ATOM 3193 C C . GLY C 1 40 ? 21.723 30.504 28.045 1.00 28.61 ? 40 GLY B C 1 ATOM 3194 O O . GLY C 1 40 ? 21.991 29.815 29.033 1.00 28.76 ? 40 GLY B O 1 ATOM 3195 N N . GLU C 1 41 ? 22.236 31.712 27.811 1.00 30.30 ? 41 GLU B N 1 ATOM 3196 C CA . GLU C 1 41 ? 23.150 32.453 28.697 1.00 32.11 ? 41 GLU B CA 1 ATOM 3197 C C . GLU C 1 41 ? 22.675 32.471 30.161 1.00 32.58 ? 41 GLU B C 1 ATOM 3198 O O . GLU C 1 41 ? 23.473 32.693 31.070 1.00 32.99 ? 41 GLU B O 1 ATOM 3199 C CB . GLU C 1 41 ? 23.272 33.881 28.154 1.00 32.36 ? 41 GLU B CB 1 ATOM 3200 C CG . GLU C 1 41 ? 24.490 34.735 28.545 1.00 35.96 ? 41 GLU B CG 1 ATOM 3201 C CD . GLU C 1 41 ? 24.524 36.094 27.757 1.00 42.89 ? 41 GLU B CD 1 ATOM 3202 O OE1 . GLU C 1 41 ? 24.404 37.193 28.380 1.00 44.04 ? 41 GLU B OE1 1 ATOM 3203 O OE2 . GLU C 1 41 ? 24.629 36.066 26.495 1.00 45.37 ? 41 GLU B OE2 1 ATOM 3204 N N . HIS C 1 42 ? 21.384 32.213 30.376 1.00 32.96 ? 42 HIS B N 1 ATOM 3205 C CA . HIS C 1 42 ? 20.771 32.268 31.692 1.00 33.39 ? 42 HIS B CA 1 ATOM 3206 C C . HIS C 1 42 ? 19.794 31.127 31.905 1.00 32.55 ? 42 HIS B C 1 ATOM 3207 O O . HIS C 1 42 ? 18.973 31.180 32.822 1.00 32.58 ? 42 HIS B O 1 ATOM 3208 C CB . HIS C 1 42 ? 20.012 33.593 31.836 1.00 34.50 ? 42 HIS B CB 1 ATOM 3209 C CG . HIS C 1 42 ? 20.901 34.798 31.786 1.00 39.23 ? 42 HIS B CG 1 ATOM 3210 N ND1 . HIS C 1 42 ? 21.550 35.198 30.632 1.00 41.90 ? 42 HIS B ND1 1 ATOM 3211 C CD2 . HIS C 1 42 ? 21.272 35.676 32.753 1.00 42.55 ? 42 HIS B CD2 1 ATOM 3212 C CE1 . HIS C 1 42 ? 22.283 36.268 30.891 1.00 43.24 ? 42 HIS B CE1 1 ATOM 3213 N NE2 . HIS C 1 42 ? 22.134 36.577 32.171 1.00 44.49 ? 42 HIS B NE2 1 ATOM 3214 N N . CYS C 1 43 ? 19.849 30.110 31.049 1.00 31.62 ? 43 CYS B N 1 ATOM 3215 C CA . CYS C 1 43 ? 18.835 29.058 31.061 1.00 30.85 ? 43 CYS B CA 1 ATOM 3216 C C . CYS C 1 43 ? 17.453 29.679 30.963 1.00 29.71 ? 43 CYS B C 1 ATOM 3217 O O . CYS C 1 43 ? 16.544 29.355 31.716 1.00 29.18 ? 43 CYS B O 1 ATOM 3218 C CB . CYS C 1 43 ? 18.939 28.223 32.340 1.00 31.42 ? 43 CYS B CB 1 ATOM 3219 S SG . CYS C 1 43 ? 20.640 27.884 32.893 1.00 34.17 ? 43 CYS B SG 1 ATOM 3220 N N . GLU C 1 44 ? 17.309 30.604 30.033 1.00 28.97 ? 44 GLU B N 1 ATOM 3221 C CA . GLU C 1 44 ? 16.059 31.308 29.871 1.00 28.40 ? 44 GLU B CA 1 ATOM 3222 C C . GLU C 1 44 ? 15.209 30.580 28.857 1.00 27.84 ? 44 GLU B C 1 ATOM 3223 O O . GLU C 1 44 ? 13.998 30.784 28.783 1.00 27.85 ? 44 GLU B O 1 ATOM 3224 C CB . GLU C 1 44 ? 16.309 32.750 29.445 1.00 28.44 ? 44 GLU B CB 1 ATOM 3225 C CG . GLU C 1 44 ? 16.986 32.945 28.078 1.00 30.66 ? 44 GLU B CG 1 ATOM 3226 C CD . GLU C 1 44 ? 18.520 32.952 28.127 1.00 33.89 ? 44 GLU B CD 1 ATOM 3227 O OE1 . GLU C 1 44 ? 19.120 31.990 28.664 1.00 34.43 ? 44 GLU B OE1 1 ATOM 3228 O OE2 . GLU C 1 44 ? 19.126 33.922 27.606 1.00 35.35 ? 44 GLU B OE2 1 ATOM 3229 N N . ILE C 1 45 ? 15.851 29.705 28.092 1.00 27.33 ? 45 ILE B N 1 ATOM 3230 C CA . ILE C 1 45 ? 15.198 29.045 26.983 1.00 26.92 ? 45 ILE B CA 1 ATOM 3231 C C . ILE C 1 45 ? 14.814 27.639 27.370 1.00 26.90 ? 45 ILE B C 1 ATOM 3232 O O . ILE C 1 45 ? 15.672 26.863 27.753 1.00 27.06 ? 45 ILE B O 1 ATOM 3233 C CB . ILE C 1 45 ? 16.095 28.993 25.746 1.00 26.64 ? 45 ILE B CB 1 ATOM 3234 C CG1 . ILE C 1 45 ? 17.033 30.188 25.720 1.00 26.49 ? 45 ILE B CG1 1 ATOM 3235 C CG2 . ILE C 1 45 ? 15.244 28.990 24.494 1.00 27.13 ? 45 ILE B CG2 1 ATOM 3236 C CD1 . ILE C 1 45 ? 18.040 30.138 24.647 1.00 27.52 ? 45 ILE B CD1 1 ATOM 3237 N N . ASP C 1 46 ? 13.518 27.333 27.271 1.00 27.14 ? 46 ASP B N 1 ATOM 3238 C CA . ASP C 1 46 ? 12.955 25.999 27.534 1.00 26.98 ? 46 ASP B CA 1 ATOM 3239 C C . ASP C 1 46 ? 12.935 25.203 26.254 1.00 27.49 ? 46 ASP B C 1 ATOM 3240 O O . ASP C 1 46 ? 12.064 25.365 25.410 1.00 28.28 ? 46 ASP B O 1 ATOM 3241 C CB . ASP C 1 46 ? 11.524 26.102 28.081 1.00 26.47 ? 46 ASP B CB 1 ATOM 3242 C CG . ASP C 1 46 ? 10.854 24.747 28.246 1.00 25.53 ? 46 ASP B CG 1 ATOM 3243 O OD1 . ASP C 1 46 ? 11.414 23.717 27.800 1.00 23.35 ? 46 ASP B OD1 1 ATOM 3244 O OD2 . ASP C 1 46 ? 9.752 24.722 28.830 1.00 25.16 ? 46 ASP B OD2 1 ATOM 3245 N N . ALA C 1 47 ? 13.890 24.322 26.101 1.00 27.84 ? 47 ALA B N 1 ATOM 3246 C CA . ALA C 1 47 ? 13.997 23.621 24.856 1.00 28.50 ? 47 ALA B CA 1 ATOM 3247 C C . ALA C 1 47 ? 12.982 22.467 24.715 1.00 29.10 ? 47 ALA B C 1 ATOM 3248 O O . ALA C 1 47 ? 13.045 21.697 23.759 1.00 29.03 ? 47 ALA B O 1 ATOM 3249 C CB . ALA C 1 47 ? 15.438 23.152 24.659 1.00 28.47 ? 47 ALA B CB 1 ATOM 3250 N N . SER C 1 48 ? 12.037 22.337 25.639 1.00 30.21 ? 48 SER B N 1 ATOM 3251 C CA . SER C 1 48 ? 11.116 21.201 25.551 1.00 31.66 ? 48 SER B CA 1 ATOM 3252 C C . SER C 1 48 ? 9.736 21.630 25.099 1.00 32.94 ? 48 SER B C 1 ATOM 3253 O O . SER C 1 48 ? 8.883 20.785 24.818 1.00 33.23 ? 48 SER B O 1 ATOM 3254 C CB . SER C 1 48 ? 10.999 20.477 26.876 1.00 31.34 ? 48 SER B CB 1 ATOM 3255 O OG . SER C 1 48 ? 10.115 21.187 27.717 1.00 32.08 ? 48 SER B OG 1 ATOM 3256 N N . LYS C 1 49 ? 9.514 22.937 25.030 1.00 34.25 ? 49 LYS B N 1 ATOM 3257 C CA . LYS C 1 49 ? 8.224 23.443 24.626 1.00 35.55 ? 49 LYS B CA 1 ATOM 3258 C C . LYS C 1 49 ? 7.964 23.310 23.125 1.00 36.76 ? 49 LYS B C 1 ATOM 3259 O O . LYS C 1 49 ? 8.882 23.408 22.314 1.00 36.91 ? 49 LYS B O 1 ATOM 3260 C CB . LYS C 1 49 ? 8.046 24.875 25.095 1.00 35.38 ? 49 LYS B CB 1 ATOM 3261 C CG . LYS C 1 49 ? 7.394 24.953 26.458 1.00 35.61 ? 49 LYS B CG 1 ATOM 3262 C CD . LYS C 1 49 ? 6.290 26.016 26.486 1.00 35.34 ? 49 LYS B CD 1 ATOM 3263 C CE . LYS C 1 49 ? 5.037 25.576 25.704 1.00 33.61 ? 49 LYS B CE 1 ATOM 3264 N NZ . LYS C 1 49 ? 4.024 26.668 25.584 1.00 32.24 ? 49 LYS B NZ 1 ATOM 3265 N N . THR C 1 50 ? 6.691 23.099 22.789 1.00 38.23 ? 50 THR B N 1 ATOM 3266 C CA . THR C 1 50 ? 6.209 22.814 21.431 1.00 39.48 ? 50 THR B CA 1 ATOM 3267 C C . THR C 1 50 ? 4.984 23.706 21.071 1.00 40.17 ? 50 THR B C 1 ATOM 3268 O O . THR C 1 50 ? 5.006 24.389 20.058 1.00 40.14 ? 50 THR B O 1 ATOM 3269 C CB . THR C 1 50 ? 5.946 21.261 21.224 1.00 39.67 ? 50 THR B CB 1 ATOM 3270 O OG1 . THR C 1 50 ? 4.796 21.041 20.396 1.00 40.72 ? 50 THR B OG1 1 ATOM 3271 C CG2 . THR C 1 50 ? 5.704 20.521 22.565 1.00 40.15 ? 50 THR B CG2 1 ATOM 3272 N N . CYS C 1 51 ? 3.936 23.703 21.903 1.00 41.25 ? 51 CYS B N 1 ATOM 3273 C CA . CYS C 1 51 ? 2.801 24.635 21.779 1.00 42.44 ? 51 CYS B CA 1 ATOM 3274 C C . CYS C 1 51 ? 3.135 26.036 22.336 1.00 42.00 ? 51 CYS B C 1 ATOM 3275 O O . CYS C 1 51 ? 4.214 26.244 22.889 1.00 41.98 ? 51 CYS B O 1 ATOM 3276 C CB . CYS C 1 51 ? 1.575 24.071 22.516 1.00 43.21 ? 51 CYS B CB 1 ATOM 3277 S SG . CYS C 1 51 ? 0.057 25.128 22.416 1.00 48.48 ? 51 CYS B SG 1 ATOM 3278 N N . TYR C 1 52 ? 2.213 26.990 22.188 1.00 41.69 ? 52 TYR B N 1 ATOM 3279 C CA . TYR C 1 52 ? 2.285 28.269 22.919 1.00 41.54 ? 52 TYR B CA 1 ATOM 3280 C C . TYR C 1 52 ? 1.044 28.537 23.821 1.00 41.16 ? 52 TYR B C 1 ATOM 3281 O O . TYR C 1 52 ? -0.074 28.679 23.331 1.00 40.92 ? 52 TYR B O 1 ATOM 3282 C CB . TYR C 1 52 ? 2.617 29.447 21.973 1.00 41.82 ? 52 TYR B CB 1 ATOM 3283 C CG . TYR C 1 52 ? 1.505 29.892 21.037 1.00 42.85 ? 52 TYR B CG 1 ATOM 3284 C CD1 . TYR C 1 52 ? 0.822 31.089 21.261 1.00 43.41 ? 52 TYR B CD1 1 ATOM 3285 C CD2 . TYR C 1 52 ? 1.136 29.121 19.927 1.00 43.92 ? 52 TYR B CD2 1 ATOM 3286 C CE1 . TYR C 1 52 ? -0.208 31.502 20.417 1.00 43.38 ? 52 TYR B CE1 1 ATOM 3287 C CE2 . TYR C 1 52 ? 0.107 29.526 19.075 1.00 43.47 ? 52 TYR B CE2 1 ATOM 3288 C CZ . TYR C 1 52 ? -0.557 30.716 19.331 1.00 43.47 ? 52 TYR B CZ 1 ATOM 3289 O OH . TYR C 1 52 ? -1.570 31.131 18.502 1.00 43.17 ? 52 TYR B OH 1 ATOM 3290 N N . HIS C 1 53 ? 1.274 28.577 25.140 1.00 40.83 ? 53 HIS B N 1 ATOM 3291 C CA . HIS C 1 53 ? 0.234 28.677 26.187 1.00 40.22 ? 53 HIS B CA 1 ATOM 3292 C C . HIS C 1 53 ? -0.788 29.777 25.932 1.00 39.29 ? 53 HIS B C 1 ATOM 3293 O O . HIS C 1 53 ? -0.499 30.944 26.181 1.00 39.27 ? 53 HIS B O 1 ATOM 3294 C CB . HIS C 1 53 ? 0.887 28.943 27.562 1.00 40.69 ? 53 HIS B CB 1 ATOM 3295 C CG . HIS C 1 53 ? 0.812 27.794 28.532 1.00 42.60 ? 53 HIS B CG 1 ATOM 3296 N ND1 . HIS C 1 53 ? 1.903 27.368 29.266 1.00 44.31 ? 53 HIS B ND1 1 ATOM 3297 C CD2 . HIS C 1 53 ? -0.226 27.010 28.918 1.00 43.88 ? 53 HIS B CD2 1 ATOM 3298 C CE1 . HIS C 1 53 ? 1.546 26.360 30.044 1.00 44.52 ? 53 HIS B CE1 1 ATOM 3299 N NE2 . HIS C 1 53 ? 0.259 26.123 29.851 1.00 44.74 ? 53 HIS B NE2 1 ATOM 3300 N N . GLY C 1 54 ? -1.980 29.395 25.466 1.00 38.37 ? 54 GLY B N 1 ATOM 3301 C CA . GLY C 1 54 ? -3.104 30.322 25.234 1.00 37.05 ? 54 GLY B CA 1 ATOM 3302 C C . GLY C 1 54 ? -2.721 31.504 24.369 1.00 36.33 ? 54 GLY B C 1 ATOM 3303 O O . GLY C 1 54 ? -2.830 31.463 23.145 1.00 36.33 ? 54 GLY B O 1 ATOM 3304 N N . ASN C 1 55 ? -2.263 32.563 25.018 1.00 35.55 ? 55 ASN B N 1 ATOM 3305 C CA . ASN C 1 55 ? -1.620 33.657 24.325 1.00 34.80 ? 55 ASN B CA 1 ATOM 3306 C C . ASN C 1 55 ? -0.147 33.340 24.079 1.00 34.36 ? 55 ASN B C 1 ATOM 3307 O O . ASN C 1 55 ? 0.292 32.204 24.254 1.00 34.37 ? 55 ASN B O 1 ATOM 3308 C CB . ASN C 1 55 ? -1.734 34.923 25.156 1.00 34.87 ? 55 ASN B CB 1 ATOM 3309 C CG . ASN C 1 55 ? -1.284 36.134 24.402 1.00 35.14 ? 55 ASN B CG 1 ATOM 3310 O OD1 . ASN C 1 55 ? -1.780 36.404 23.311 1.00 36.78 ? 55 ASN B OD1 1 ATOM 3311 N ND2 . ASN C 1 55 ? -0.331 36.869 24.962 1.00 34.62 ? 55 ASN B ND2 1 ATOM 3312 N N . GLY C 1 56 ? 0.625 34.341 23.682 1.00 33.75 ? 56 GLY B N 1 ATOM 3313 C CA . GLY C 1 56 ? 2.047 34.137 23.475 1.00 33.17 ? 56 GLY B CA 1 ATOM 3314 C C . GLY C 1 56 ? 2.886 34.606 24.638 1.00 32.77 ? 56 GLY B C 1 ATOM 3315 O O . GLY C 1 56 ? 4.038 34.188 24.776 1.00 32.92 ? 56 GLY B O 1 ATOM 3316 N N . ASP C 1 57 ? 2.294 35.466 25.472 1.00 32.25 ? 57 ASP B N 1 ATOM 3317 C CA . ASP C 1 57 ? 2.978 36.210 26.545 1.00 31.67 ? 57 ASP B CA 1 ATOM 3318 C C . ASP C 1 57 ? 4.031 35.398 27.288 1.00 31.44 ? 57 ASP B C 1 ATOM 3319 O O . ASP C 1 57 ? 5.178 35.834 27.457 1.00 31.39 ? 57 ASP B O 1 ATOM 3320 C CB . ASP C 1 57 ? 1.948 36.733 27.547 1.00 31.63 ? 57 ASP B CB 1 ATOM 3321 C CG . ASP C 1 57 ? 0.974 35.650 28.008 1.00 32.29 ? 57 ASP B CG 1 ATOM 3322 O OD1 . ASP C 1 57 ? -0.180 35.980 28.377 1.00 33.17 ? 57 ASP B OD1 1 ATOM 3323 O OD2 . ASP C 1 57 ? 1.353 34.459 27.986 1.00 32.05 ? 57 ASP B OD2 1 ATOM 3324 N N . SER C 1 58 ? 3.622 34.208 27.717 1.00 30.92 ? 58 SER B N 1 ATOM 3325 C CA . SER C 1 58 ? 4.454 33.342 28.523 1.00 30.27 ? 58 SER B CA 1 ATOM 3326 C C . SER C 1 58 ? 5.433 32.617 27.653 1.00 29.42 ? 58 SER B C 1 ATOM 3327 O O . SER C 1 58 ? 6.557 32.412 28.073 1.00 30.16 ? 58 SER B O 1 ATOM 3328 C CB . SER C 1 58 ? 3.607 32.331 29.281 1.00 30.51 ? 58 SER B CB 1 ATOM 3329 O OG . SER C 1 58 ? 2.501 32.975 29.905 1.00 32.22 ? 58 SER B OG 1 ATOM 3330 N N . TYR C 1 59 ? 5.022 32.238 26.443 1.00 28.27 ? 59 TYR B N 1 ATOM 3331 C CA . TYR C 1 59 ? 5.853 31.404 25.568 1.00 26.90 ? 59 TYR B CA 1 ATOM 3332 C C . TYR C 1 59 ? 7.320 31.833 25.645 1.00 26.53 ? 59 TYR B C 1 ATOM 3333 O O . TYR C 1 59 ? 7.622 33.033 25.629 1.00 26.35 ? 59 TYR B O 1 ATOM 3334 C CB . TYR C 1 59 ? 5.339 31.414 24.116 1.00 26.46 ? 59 TYR B CB 1 ATOM 3335 C CG . TYR C 1 59 ? 6.232 30.634 23.165 1.00 25.02 ? 59 TYR B CG 1 ATOM 3336 C CD1 . TYR C 1 59 ? 6.208 29.249 23.147 1.00 24.66 ? 59 TYR B CD1 1 ATOM 3337 C CD2 . TYR C 1 59 ? 7.115 31.275 22.296 1.00 22.97 ? 59 TYR B CD2 1 ATOM 3338 C CE1 . TYR C 1 59 ? 7.030 28.521 22.289 1.00 22.50 ? 59 TYR B CE1 1 ATOM 3339 C CE2 . TYR C 1 59 ? 7.940 30.547 21.451 1.00 21.02 ? 59 TYR B CE2 1 ATOM 3340 C CZ . TYR C 1 59 ? 7.882 29.175 21.458 1.00 20.73 ? 59 TYR B CZ 1 ATOM 3341 O OH . TYR C 1 59 ? 8.674 28.422 20.649 1.00 20.78 ? 59 TYR B OH 1 ATOM 3342 N N . ARG C 1 60 ? 8.214 30.853 25.748 1.00 25.91 ? 60 ARG B N 1 ATOM 3343 C CA . ARG C 1 60 ? 9.643 31.116 25.890 1.00 25.77 ? 60 ARG B CA 1 ATOM 3344 C C . ARG C 1 60 ? 10.491 30.077 25.138 1.00 25.73 ? 60 ARG B C 1 ATOM 3345 O O . ARG C 1 60 ? 11.662 29.818 25.480 1.00 25.44 ? 60 ARG B O 1 ATOM 3346 C CB . ARG C 1 60 ? 10.003 31.120 27.374 1.00 25.74 ? 60 ARG B CB 1 ATOM 3347 C CG . ARG C 1 60 ? 11.059 32.140 27.739 1.00 26.11 ? 60 ARG B CG 1 ATOM 3348 C CD . ARG C 1 60 ? 10.544 33.581 27.586 1.00 24.80 ? 60 ARG B CD 1 ATOM 3349 N NE . ARG C 1 60 ? 9.193 33.773 28.119 1.00 22.57 ? 60 ARG B NE 1 ATOM 3350 C CZ . ARG C 1 60 ? 8.539 34.928 28.083 1.00 22.81 ? 60 ARG B CZ 1 ATOM 3351 N NH1 . ARG C 1 60 ? 9.108 35.996 27.553 1.00 24.51 ? 60 ARG B NH1 1 ATOM 3352 N NH2 . ARG C 1 60 ? 7.315 35.029 28.571 1.00 23.13 ? 60 ARG B NH2 1 ATOM 3353 N N . GLY C 1 61 ? 9.883 29.505 24.100 1.00 25.56 ? 61 GLY B N 1 ATOM 3354 C CA . GLY C 1 61 ? 10.421 28.338 23.409 1.00 25.60 ? 61 GLY B CA 1 ATOM 3355 C C . GLY C 1 61 ? 11.506 28.590 22.377 1.00 25.58 ? 61 GLY B C 1 ATOM 3356 O O . GLY C 1 61 ? 12.262 29.581 22.477 1.00 25.58 ? 61 GLY B O 1 ATOM 3357 N N . LYS C 1 62 ? 11.576 27.690 21.388 1.00 24.93 ? 62 LYS B N 1 ATOM 3358 C CA . LYS C 1 62 ? 12.697 27.665 20.450 1.00 24.64 ? 62 LYS B CA 1 ATOM 3359 C C . LYS C 1 62 ? 12.342 27.828 18.964 1.00 25.14 ? 62 LYS B C 1 ATOM 3360 O O . LYS C 1 62 ? 13.225 27.708 18.100 1.00 24.96 ? 62 LYS B O 1 ATOM 3361 C CB . LYS C 1 62 ? 13.546 26.416 20.654 1.00 24.28 ? 62 LYS B CB 1 ATOM 3362 C CG . LYS C 1 62 ? 14.373 26.414 21.921 1.00 23.08 ? 62 LYS B CG 1 ATOM 3363 C CD . LYS C 1 62 ? 15.859 26.140 21.628 1.00 20.38 ? 62 LYS B CD 1 ATOM 3364 C CE . LYS C 1 62 ? 16.186 24.666 21.441 1.00 15.99 ? 62 LYS B CE 1 ATOM 3365 N NZ . LYS C 1 62 ? 17.548 24.556 20.854 1.00 14.44 ? 62 LYS B NZ 1 ATOM 3366 N N . ALA C 1 63 ? 11.066 28.105 18.681 1.00 25.63 ? 63 ALA B N 1 ATOM 3367 C CA . ALA C 1 63 ? 10.575 28.372 17.325 1.00 26.13 ? 63 ALA B CA 1 ATOM 3368 C C . ALA C 1 63 ? 11.396 29.424 16.614 1.00 26.79 ? 63 ALA B C 1 ATOM 3369 O O . ALA C 1 63 ? 11.639 30.509 17.112 1.00 27.04 ? 63 ALA B O 1 ATOM 3370 C CB . ALA C 1 63 ? 9.142 28.798 17.355 1.00 26.11 ? 63 ALA B CB 1 ATOM 3371 N N . ASN C 1 64 ? 11.801 29.099 15.412 1.00 27.67 ? 64 ASN B N 1 ATOM 3372 C CA . ASN C 1 64 ? 12.753 29.908 14.736 1.00 28.16 ? 64 ASN B CA 1 ATOM 3373 C C . ASN C 1 64 ? 12.169 30.792 13.626 1.00 28.03 ? 64 ASN B C 1 ATOM 3374 O O . ASN C 1 64 ? 12.714 31.852 13.350 1.00 28.44 ? 64 ASN B O 1 ATOM 3375 C CB . ASN C 1 64 ? 13.841 29.000 14.181 1.00 28.48 ? 64 ASN B CB 1 ATOM 3376 C CG . ASN C 1 64 ? 15.095 29.751 13.898 1.00 31.63 ? 64 ASN B CG 1 ATOM 3377 O OD1 . ASN C 1 64 ? 15.566 30.505 14.763 1.00 33.74 ? 64 ASN B OD1 1 ATOM 3378 N ND2 . ASN C 1 64 ? 15.635 29.609 12.667 1.00 33.92 ? 64 ASN B ND2 1 ATOM 3379 N N . THR C 1 65 ? 11.076 30.367 12.986 1.00 27.70 ? 65 THR B N 1 ATOM 3380 C CA . THR C 1 65 ? 10.667 30.953 11.689 1.00 27.23 ? 65 THR B CA 1 ATOM 3381 C C . THR C 1 65 ? 9.219 31.412 11.561 1.00 26.90 ? 65 THR B C 1 ATOM 3382 O O . THR C 1 65 ? 8.341 30.908 12.243 1.00 26.89 ? 65 THR B O 1 ATOM 3383 C CB . THR C 1 65 ? 10.901 29.977 10.547 1.00 27.17 ? 65 THR B CB 1 ATOM 3384 O OG1 . THR C 1 65 ? 10.016 28.865 10.705 1.00 26.83 ? 65 THR B OG1 1 ATOM 3385 C CG2 . THR C 1 65 ? 12.371 29.510 10.513 1.00 27.36 ? 65 THR B CG2 1 ATOM 3386 N N . ASP C 1 66 ? 8.975 32.334 10.636 1.00 26.53 ? 66 ASP B N 1 ATOM 3387 C CA . ASP C 1 66 ? 7.658 32.965 10.503 1.00 26.34 ? 66 ASP B CA 1 ATOM 3388 C C . ASP C 1 66 ? 6.602 32.033 9.929 1.00 25.90 ? 66 ASP B C 1 ATOM 3389 O O . ASP C 1 66 ? 6.895 30.883 9.607 1.00 25.52 ? 66 ASP B O 1 ATOM 3390 C CB . ASP C 1 66 ? 7.749 34.205 9.620 1.00 26.59 ? 66 ASP B CB 1 ATOM 3391 C CG . ASP C 1 66 ? 8.054 33.864 8.172 1.00 26.78 ? 66 ASP B CG 1 ATOM 3392 O OD1 . ASP C 1 66 ? 8.199 34.797 7.357 1.00 26.46 ? 66 ASP B OD1 1 ATOM 3393 O OD2 . ASP C 1 66 ? 8.161 32.661 7.856 1.00 27.18 ? 66 ASP B OD2 1 ATOM 3394 N N . THR C 1 67 ? 5.388 32.565 9.767 1.00 25.68 ? 67 THR B N 1 ATOM 3395 C CA . THR C 1 67 ? 4.229 31.775 9.342 1.00 25.48 ? 67 THR B CA 1 ATOM 3396 C C . THR C 1 67 ? 4.604 31.036 8.107 1.00 25.11 ? 67 THR B C 1 ATOM 3397 O O . THR C 1 67 ? 4.320 29.849 7.990 1.00 25.29 ? 67 THR B O 1 ATOM 3398 C CB . THR C 1 67 ? 3.014 32.633 8.953 1.00 25.48 ? 67 THR B CB 1 ATOM 3399 O OG1 . THR C 1 67 ? 3.046 33.878 9.657 1.00 26.77 ? 67 THR B OG1 1 ATOM 3400 C CG2 . THR C 1 67 ? 1.714 31.894 9.255 1.00 25.19 ? 67 THR B CG2 1 ATOM 3401 N N . LYS C 1 68 ? 5.281 31.759 7.213 1.00 24.62 ? 68 LYS B N 1 ATOM 3402 C CA . LYS C 1 68 ? 5.538 31.324 5.849 1.00 23.79 ? 68 LYS B CA 1 ATOM 3403 C C . LYS C 1 68 ? 7.016 31.069 5.568 1.00 23.16 ? 68 LYS B C 1 ATOM 3404 O O . LYS C 1 68 ? 7.501 31.379 4.483 1.00 22.75 ? 68 LYS B O 1 ATOM 3405 C CB . LYS C 1 68 ? 5.005 32.380 4.899 1.00 23.82 ? 68 LYS B CB 1 ATOM 3406 C CG . LYS C 1 68 ? 3.648 32.952 5.319 1.00 25.05 ? 68 LYS B CG 1 ATOM 3407 C CD . LYS C 1 68 ? 3.231 34.121 4.445 1.00 26.67 ? 68 LYS B CD 1 ATOM 3408 C CE . LYS C 1 68 ? 4.263 35.237 4.518 1.00 28.66 ? 68 LYS B CE 1 ATOM 3409 N NZ . LYS C 1 68 ? 5.617 34.761 4.080 1.00 29.44 ? 68 LYS B NZ 1 ATOM 3410 N N . GLY C 1 69 ? 7.728 30.548 6.573 1.00 22.71 ? 69 GLY B N 1 ATOM 3411 C CA . GLY C 1 69 ? 9.065 29.976 6.396 1.00 22.15 ? 69 GLY B CA 1 ATOM 3412 C C . GLY C 1 69 ? 10.314 30.841 6.504 1.00 21.77 ? 69 GLY B C 1 ATOM 3413 O O . GLY C 1 69 ? 11.424 30.330 6.570 1.00 21.86 ? 69 GLY B O 1 ATOM 3414 N N . ARG C 1 70 ? 10.183 32.149 6.496 1.00 21.41 ? 70 ARG B N 1 ATOM 3415 C CA . ARG C 1 70 ? 11.392 32.932 6.657 1.00 21.32 ? 70 ARG B CA 1 ATOM 3416 C C . ARG C 1 70 ? 11.976 32.816 8.079 1.00 21.14 ? 70 ARG B C 1 ATOM 3417 O O . ARG C 1 70 ? 11.237 32.782 9.071 1.00 20.70 ? 70 ARG B O 1 ATOM 3418 C CB . ARG C 1 70 ? 11.182 34.403 6.274 1.00 21.43 ? 70 ARG B CB 1 ATOM 3419 C CG . ARG C 1 70 ? 11.395 34.750 4.785 1.00 21.44 ? 70 ARG B CG 1 ATOM 3420 C CD . ARG C 1 70 ? 10.089 35.174 4.053 1.00 18.84 ? 70 ARG B CD 1 ATOM 3421 N NE . ARG C 1 70 ? 9.164 35.868 4.954 1.00 17.37 ? 70 ARG B NE 1 ATOM 3422 C CZ . ARG C 1 70 ? 8.152 36.635 4.572 1.00 16.35 ? 70 ARG B CZ 1 ATOM 3423 N NH1 . ARG C 1 70 ? 7.922 36.827 3.286 1.00 18.54 ? 70 ARG B NH1 1 ATOM 3424 N NH2 . ARG C 1 70 ? 7.367 37.211 5.476 1.00 15.28 ? 70 ARG B NH2 1 ATOM 3425 N N . PRO C 1 71 ? 13.307 32.710 8.157 1.00 20.98 ? 71 PRO B N 1 ATOM 3426 C CA . PRO C 1 71 ? 14.156 32.895 9.302 1.00 20.94 ? 71 PRO B CA 1 ATOM 3427 C C . PRO C 1 71 ? 13.853 34.185 9.988 1.00 21.11 ? 71 PRO B C 1 ATOM 3428 O O . PRO C 1 71 ? 13.778 35.205 9.308 1.00 20.78 ? 71 PRO B O 1 ATOM 3429 C CB . PRO C 1 71 ? 15.523 33.060 8.661 1.00 20.58 ? 71 PRO B CB 1 ATOM 3430 C CG . PRO C 1 71 ? 15.489 32.160 7.534 1.00 21.45 ? 71 PRO B CG 1 ATOM 3431 C CD . PRO C 1 71 ? 14.047 32.046 7.075 1.00 21.41 ? 71 PRO B CD 1 ATOM 3432 N N . CYS C 1 72 ? 13.713 34.146 11.318 1.00 21.64 ? 72 CYS B N 1 ATOM 3433 C CA . CYS C 1 72 ? 13.694 35.369 12.112 1.00 22.37 ? 72 CYS B CA 1 ATOM 3434 C C . CYS C 1 72 ? 15.108 35.895 12.286 1.00 22.39 ? 72 CYS B C 1 ATOM 3435 O O . CYS C 1 72 ? 16.097 35.269 11.870 1.00 22.05 ? 72 CYS B O 1 ATOM 3436 C CB . CYS C 1 72 ? 13.101 35.139 13.480 1.00 22.65 ? 72 CYS B CB 1 ATOM 3437 S SG . CYS C 1 72 ? 11.475 34.389 13.507 1.00 26.15 ? 72 CYS B SG 1 ATOM 3438 N N . LEU C 1 73 ? 15.196 37.056 12.923 1.00 22.76 ? 73 LEU B N 1 ATOM 3439 C CA . LEU C 1 73 ? 16.483 37.741 13.123 1.00 22.76 ? 73 LEU B CA 1 ATOM 3440 C C . LEU C 1 73 ? 16.826 37.861 14.619 1.00 22.54 ? 73 LEU B C 1 ATOM 3441 O O . LEU C 1 73 ? 15.986 38.270 15.438 1.00 22.25 ? 73 LEU B O 1 ATOM 3442 C CB . LEU C 1 73 ? 16.452 39.127 12.454 1.00 22.78 ? 73 LEU B CB 1 ATOM 3443 C CG . LEU C 1 73 ? 15.812 39.268 11.068 1.00 20.94 ? 73 LEU B CG 1 ATOM 3444 C CD1 . LEU C 1 73 ? 15.133 40.633 10.935 1.00 18.49 ? 73 LEU B CD1 1 ATOM 3445 C CD2 . LEU C 1 73 ? 16.852 39.009 9.963 1.00 19.81 ? 73 LEU B CD2 1 ATOM 3446 N N . ALA C 1 74 ? 18.053 37.489 14.960 1.00 22.27 ? 74 ALA B N 1 ATOM 3447 C CA . ALA C 1 74 ? 18.489 37.511 16.344 1.00 22.40 ? 74 ALA B CA 1 ATOM 3448 C C . ALA C 1 74 ? 18.105 38.850 16.924 1.00 22.58 ? 74 ALA B C 1 ATOM 3449 O O . ALA C 1 74 ? 18.452 39.883 16.358 1.00 23.16 ? 74 ALA B O 1 ATOM 3450 C CB . ALA C 1 74 ? 20.014 37.316 16.440 1.00 22.34 ? 74 ALA B CB 1 ATOM 3451 N N . TRP C 1 75 ? 17.382 38.844 18.038 1.00 22.50 ? 75 TRP B N 1 ATOM 3452 C CA . TRP C 1 75 ? 17.045 40.088 18.734 1.00 22.36 ? 75 TRP B CA 1 ATOM 3453 C C . TRP C 1 75 ? 18.286 40.871 19.114 1.00 22.37 ? 75 TRP B C 1 ATOM 3454 O O . TRP C 1 75 ? 18.196 41.896 19.766 1.00 22.13 ? 75 TRP B O 1 ATOM 3455 C CB . TRP C 1 75 ? 16.256 39.802 19.993 1.00 22.33 ? 75 TRP B CB 1 ATOM 3456 C CG . TRP C 1 75 ? 15.187 38.820 19.807 1.00 22.17 ? 75 TRP B CG 1 ATOM 3457 C CD1 . TRP C 1 75 ? 15.304 37.469 19.904 1.00 23.04 ? 75 TRP B CD1 1 ATOM 3458 C CD2 . TRP C 1 75 ? 13.818 39.090 19.506 1.00 21.15 ? 75 TRP B CD2 1 ATOM 3459 N NE1 . TRP C 1 75 ? 14.088 36.878 19.685 1.00 23.64 ? 75 TRP B NE1 1 ATOM 3460 C CE2 . TRP C 1 75 ? 13.158 37.856 19.438 1.00 22.68 ? 75 TRP B CE2 1 ATOM 3461 C CE3 . TRP C 1 75 ? 13.086 40.253 19.296 1.00 21.30 ? 75 TRP B CE3 1 ATOM 3462 C CZ2 . TRP C 1 75 ? 11.790 37.751 19.163 1.00 23.27 ? 75 TRP B CZ2 1 ATOM 3463 C CZ3 . TRP C 1 75 ? 11.731 40.152 19.018 1.00 21.70 ? 75 TRP B CZ3 1 ATOM 3464 C CH2 . TRP C 1 75 ? 11.099 38.911 18.954 1.00 22.89 ? 75 TRP B CH2 1 ATOM 3465 N N . ASN C 1 76 ? 19.438 40.373 18.699 1.00 22.68 ? 76 ASN B N 1 ATOM 3466 C CA . ASN C 1 76 ? 20.676 41.017 18.985 1.00 23.58 ? 76 ASN B CA 1 ATOM 3467 C C . ASN C 1 76 ? 21.408 41.403 17.698 1.00 24.05 ? 76 ASN B C 1 ATOM 3468 O O . ASN C 1 76 ? 22.490 42.022 17.714 1.00 24.15 ? 76 ASN B O 1 ATOM 3469 C CB . ASN C 1 76 ? 21.499 40.123 19.901 1.00 23.74 ? 76 ASN B CB 1 ATOM 3470 C CG . ASN C 1 76 ? 22.208 39.037 19.163 1.00 25.05 ? 76 ASN B CG 1 ATOM 3471 O OD1 . ASN C 1 76 ? 23.313 39.236 18.649 1.00 26.59 ? 76 ASN B OD1 1 ATOM 3472 N ND2 . ASN C 1 76 ? 21.601 37.863 19.123 1.00 26.65 ? 76 ASN B ND2 1 ATOM 3473 N N . ALA C 1 77 ? 20.783 41.060 16.579 1.00 24.72 ? 77 ALA B N 1 ATOM 3474 C CA . ALA C 1 77 ? 21.267 41.449 15.260 1.00 25.30 ? 77 ALA B CA 1 ATOM 3475 C C . ALA C 1 77 ? 21.123 42.954 15.060 1.00 25.76 ? 77 ALA B C 1 ATOM 3476 O O . ALA C 1 77 ? 20.093 43.539 15.414 1.00 25.43 ? 77 ALA B O 1 ATOM 3477 C CB . ALA C 1 77 ? 20.513 40.698 14.187 1.00 25.64 ? 77 ALA B CB 1 ATOM 3478 N N . PRO C 1 78 ? 22.155 43.586 14.475 1.00 26.28 ? 78 PRO B N 1 ATOM 3479 C CA . PRO C 1 78 ? 22.226 45.046 14.431 1.00 26.80 ? 78 PRO B CA 1 ATOM 3480 C C . PRO C 1 78 ? 20.962 45.690 13.866 1.00 27.52 ? 78 PRO B C 1 ATOM 3481 O O . PRO C 1 78 ? 20.447 46.643 14.462 1.00 27.47 ? 78 PRO B O 1 ATOM 3482 C CB . PRO C 1 78 ? 23.446 45.323 13.537 1.00 26.58 ? 78 PRO B CB 1 ATOM 3483 C CG . PRO C 1 78 ? 23.665 44.060 12.785 1.00 26.35 ? 78 PRO B CG 1 ATOM 3484 C CD . PRO C 1 78 ? 23.245 42.963 13.706 1.00 26.18 ? 78 PRO B CD 1 ATOM 3485 N N . ALA C 1 79 ? 20.454 45.165 12.746 1.00 28.41 ? 79 ALA B N 1 ATOM 3486 C CA . ALA C 1 79 ? 19.277 45.758 12.103 1.00 29.12 ? 79 ALA B CA 1 ATOM 3487 C C . ALA C 1 79 ? 18.028 45.599 12.980 1.00 29.67 ? 79 ALA B C 1 ATOM 3488 O O . ALA C 1 79 ? 16.981 46.210 12.716 1.00 29.53 ? 79 ALA B O 1 ATOM 3489 C CB . ALA C 1 79 ? 19.064 45.184 10.730 1.00 28.94 ? 79 ALA B CB 1 ATOM 3490 N N . VAL C 1 80 ? 18.164 44.795 14.038 1.00 30.25 ? 80 VAL B N 1 ATOM 3491 C CA . VAL C 1 80 ? 17.131 44.674 15.069 1.00 30.62 ? 80 VAL B CA 1 ATOM 3492 C C . VAL C 1 80 ? 17.413 45.623 16.226 1.00 30.95 ? 80 VAL B C 1 ATOM 3493 O O . VAL C 1 80 ? 16.495 46.154 16.859 1.00 30.78 ? 80 VAL B O 1 ATOM 3494 C CB . VAL C 1 80 ? 17.042 43.251 15.617 1.00 30.41 ? 80 VAL B CB 1 ATOM 3495 C CG1 . VAL C 1 80 ? 15.748 43.068 16.429 1.00 29.55 ? 80 VAL B CG1 1 ATOM 3496 C CG2 . VAL C 1 80 ? 17.131 42.263 14.479 1.00 30.45 ? 80 VAL B CG2 1 ATOM 3497 N N . LEU C 1 81 ? 18.689 45.841 16.500 1.00 31.46 ? 81 LEU B N 1 ATOM 3498 C CA . LEU C 1 81 ? 19.039 46.704 17.601 1.00 32.36 ? 81 LEU B CA 1 ATOM 3499 C C . LEU C 1 81 ? 18.298 48.041 17.546 1.00 32.90 ? 81 LEU B C 1 ATOM 3500 O O . LEU C 1 81 ? 17.951 48.568 18.598 1.00 33.21 ? 81 LEU B O 1 ATOM 3501 C CB . LEU C 1 81 ? 20.562 46.875 17.724 1.00 32.43 ? 81 LEU B CB 1 ATOM 3502 C CG . LEU C 1 81 ? 21.296 45.674 18.352 1.00 33.42 ? 81 LEU B CG 1 ATOM 3503 C CD1 . LEU C 1 81 ? 22.808 45.688 18.110 1.00 33.37 ? 81 LEU B CD1 1 ATOM 3504 C CD2 . LEU C 1 81 ? 20.990 45.551 19.857 1.00 34.12 ? 81 LEU B CD2 1 ATOM 3505 N N . GLN C 1 82 ? 18.017 48.568 16.342 1.00 33.60 ? 82 GLN B N 1 ATOM 3506 C CA . GLN C 1 82 ? 17.393 49.914 16.186 1.00 34.02 ? 82 GLN B CA 1 ATOM 3507 C C . GLN C 1 82 ? 15.865 49.949 16.294 1.00 34.22 ? 82 GLN B C 1 ATOM 3508 O O . GLN C 1 82 ? 15.258 51.026 16.362 1.00 34.12 ? 82 GLN B O 1 ATOM 3509 C CB . GLN C 1 82 ? 17.808 50.554 14.873 1.00 33.97 ? 82 GLN B CB 1 ATOM 3510 C CG . GLN C 1 82 ? 19.277 50.848 14.777 1.00 35.17 ? 82 GLN B CG 1 ATOM 3511 C CD . GLN C 1 82 ? 19.779 50.733 13.350 1.00 37.45 ? 82 GLN B CD 1 ATOM 3512 O OE1 . GLN C 1 82 ? 19.718 49.651 12.744 1.00 38.74 ? 82 GLN B OE1 1 ATOM 3513 N NE2 . GLN C 1 82 ? 20.285 51.844 12.801 1.00 36.42 ? 82 GLN B NE2 1 ATOM 3514 N N . LYS C 1 83 ? 15.263 48.761 16.296 1.00 34.44 ? 83 LYS B N 1 ATOM 3515 C CA . LYS C 1 83 ? 13.829 48.585 16.467 1.00 34.51 ? 83 LYS B CA 1 ATOM 3516 C C . LYS C 1 83 ? 13.486 48.741 17.949 1.00 34.89 ? 83 LYS B C 1 ATOM 3517 O O . LYS C 1 83 ? 14.390 48.725 18.784 1.00 34.78 ? 83 LYS B O 1 ATOM 3518 C CB . LYS C 1 83 ? 13.441 47.188 15.984 1.00 34.40 ? 83 LYS B CB 1 ATOM 3519 C CG . LYS C 1 83 ? 13.892 46.854 14.570 1.00 33.97 ? 83 LYS B CG 1 ATOM 3520 C CD . LYS C 1 83 ? 12.872 47.324 13.537 1.00 33.60 ? 83 LYS B CD 1 ATOM 3521 C CE . LYS C 1 83 ? 13.344 47.033 12.130 1.00 32.64 ? 83 LYS B CE 1 ATOM 3522 N NZ . LYS C 1 83 ? 12.280 47.313 11.154 1.00 32.27 ? 83 LYS B NZ 1 ATOM 3523 N N . PRO C 1 84 ? 12.184 48.886 18.288 1.00 35.25 ? 84 PRO B N 1 ATOM 3524 C CA . PRO C 1 84 ? 11.758 49.006 19.691 1.00 35.58 ? 84 PRO B CA 1 ATOM 3525 C C . PRO C 1 84 ? 12.179 47.886 20.670 1.00 36.01 ? 84 PRO B C 1 ATOM 3526 O O . PRO C 1 84 ? 12.148 48.103 21.885 1.00 36.18 ? 84 PRO B O 1 ATOM 3527 C CB . PRO C 1 84 ? 10.231 49.071 19.584 1.00 35.34 ? 84 PRO B CB 1 ATOM 3528 C CG . PRO C 1 84 ? 9.986 49.702 18.291 1.00 35.33 ? 84 PRO B CG 1 ATOM 3529 C CD . PRO C 1 84 ? 11.072 49.196 17.369 1.00 35.30 ? 84 PRO B CD 1 ATOM 3530 N N . TYR C 1 85 ? 12.575 46.714 20.172 1.00 36.53 ? 85 TYR B N 1 ATOM 3531 C CA . TYR C 1 85 ? 12.813 45.560 21.061 1.00 36.95 ? 85 TYR B CA 1 ATOM 3532 C C . TYR C 1 85 ? 14.080 44.780 20.749 1.00 37.02 ? 85 TYR B C 1 ATOM 3533 O O . TYR C 1 85 ? 14.200 44.178 19.685 1.00 37.25 ? 85 TYR B O 1 ATOM 3534 C CB . TYR C 1 85 ? 11.597 44.622 21.055 1.00 36.95 ? 85 TYR B CB 1 ATOM 3535 C CG . TYR C 1 85 ? 10.321 45.277 21.561 1.00 37.67 ? 85 TYR B CG 1 ATOM 3536 C CD1 . TYR C 1 85 ? 10.089 45.439 22.933 1.00 37.92 ? 85 TYR B CD1 1 ATOM 3537 C CD2 . TYR C 1 85 ? 9.354 45.748 20.674 1.00 37.58 ? 85 TYR B CD2 1 ATOM 3538 C CE1 . TYR C 1 85 ? 8.930 46.038 23.400 1.00 37.08 ? 85 TYR B CE1 1 ATOM 3539 C CE2 . TYR C 1 85 ? 8.198 46.351 21.136 1.00 37.02 ? 85 TYR B CE2 1 ATOM 3540 C CZ . TYR C 1 85 ? 7.992 46.485 22.497 1.00 37.02 ? 85 TYR B CZ 1 ATOM 3541 O OH . TYR C 1 85 ? 6.846 47.077 22.961 1.00 37.77 ? 85 TYR B OH 1 ATOM 3542 N N . ASN C 1 86 ? 15.029 44.795 21.678 1.00 37.15 ? 86 ASN B N 1 ATOM 3543 C CA . ASN C 1 86 ? 16.310 44.130 21.455 1.00 37.39 ? 86 ASN B CA 1 ATOM 3544 C C . ASN C 1 86 ? 16.733 43.246 22.598 1.00 37.38 ? 86 ASN B C 1 ATOM 3545 O O . ASN C 1 86 ? 16.014 43.071 23.569 1.00 37.58 ? 86 ASN B O 1 ATOM 3546 C CB . ASN C 1 86 ? 17.433 45.144 21.236 1.00 37.27 ? 86 ASN B CB 1 ATOM 3547 C CG . ASN C 1 86 ? 16.940 46.451 20.713 1.00 37.84 ? 86 ASN B CG 1 ATOM 3548 O OD1 . ASN C 1 86 ? 16.112 46.507 19.793 1.00 37.57 ? 86 ASN B OD1 1 ATOM 3549 N ND2 . ASN C 1 86 ? 17.451 47.534 21.293 1.00 39.01 ? 86 ASN B ND2 1 ATOM 3550 N N . ALA C 1 87 ? 17.919 42.679 22.451 1.00 37.43 ? 87 ALA B N 1 ATOM 3551 C CA . ALA C 1 87 ? 18.647 42.150 23.570 1.00 37.49 ? 87 ALA B CA 1 ATOM 3552 C C . ALA C 1 87 ? 19.157 43.342 24.382 1.00 37.42 ? 87 ALA B C 1 ATOM 3553 O O . ALA C 1 87 ? 18.804 43.470 25.553 1.00 37.84 ? 87 ALA B O 1 ATOM 3554 C CB . ALA C 1 87 ? 19.791 41.273 23.098 1.00 37.82 ? 87 ALA B CB 1 ATOM 3555 N N . HIS C 1 88 ? 19.943 44.227 23.758 1.00 37.09 ? 88 HIS B N 1 ATOM 3556 C CA . HIS C 1 88 ? 20.462 45.444 24.423 1.00 36.81 ? 88 HIS B CA 1 ATOM 3557 C C . HIS C 1 88 ? 19.346 46.355 24.958 1.00 36.65 ? 88 HIS B C 1 ATOM 3558 O O . HIS C 1 88 ? 19.607 47.457 25.425 1.00 36.52 ? 88 HIS B O 1 ATOM 3559 C CB . HIS C 1 88 ? 21.369 46.235 23.481 1.00 36.74 ? 88 HIS B CB 1 ATOM 3560 C CG . HIS C 1 88 ? 22.522 45.449 22.939 1.00 36.76 ? 88 HIS B CG 1 ATOM 3561 N ND1 . HIS C 1 88 ? 23.561 46.037 22.253 1.00 36.64 ? 88 HIS B ND1 1 ATOM 3562 C CD2 . HIS C 1 88 ? 22.797 44.123 22.971 1.00 36.72 ? 88 HIS B CD2 1 ATOM 3563 C CE1 . HIS C 1 88 ? 24.432 45.112 21.894 1.00 36.72 ? 88 HIS B CE1 1 ATOM 3564 N NE2 . HIS C 1 88 ? 23.990 43.941 22.315 1.00 37.04 ? 88 HIS B NE2 1 ATOM 3565 N N . ARG C 1 89 ? 18.104 45.884 24.855 1.00 36.61 ? 89 ARG B N 1 ATOM 3566 C CA . ARG C 1 89 ? 16.956 46.441 25.569 1.00 36.37 ? 89 ARG B CA 1 ATOM 3567 C C . ARG C 1 89 ? 17.171 46.363 27.081 1.00 36.14 ? 89 ARG B C 1 ATOM 3568 O O . ARG C 1 89 ? 17.881 45.473 27.569 1.00 35.81 ? 89 ARG B O 1 ATOM 3569 C CB . ARG C 1 89 ? 15.703 45.638 25.219 1.00 36.46 ? 89 ARG B CB 1 ATOM 3570 C CG . ARG C 1 89 ? 14.829 46.219 24.135 1.00 36.57 ? 89 ARG B CG 1 ATOM 3571 C CD . ARG C 1 89 ? 13.837 47.205 24.697 1.00 37.48 ? 89 ARG B CD 1 ATOM 3572 N NE . ARG C 1 89 ? 13.360 46.812 26.021 1.00 38.23 ? 89 ARG B NE 1 ATOM 3573 C CZ . ARG C 1 89 ? 12.083 46.758 26.379 1.00 38.68 ? 89 ARG B CZ 1 ATOM 3574 N NH1 . ARG C 1 89 ? 11.136 47.079 25.511 1.00 38.56 ? 89 ARG B NH1 1 ATOM 3575 N NH2 . ARG C 1 89 ? 11.756 46.404 27.615 1.00 39.21 ? 89 ARG B NH2 1 ATOM 3576 N N . PRO C 1 90 ? 16.543 47.281 27.836 1.00 35.99 ? 90 PRO B N 1 ATOM 3577 C CA . PRO C 1 90 ? 16.765 47.268 29.276 1.00 35.78 ? 90 PRO B CA 1 ATOM 3578 C C . PRO C 1 90 ? 16.173 46.016 29.904 1.00 35.42 ? 90 PRO B C 1 ATOM 3579 O O . PRO C 1 90 ? 16.876 45.324 30.646 1.00 35.57 ? 90 PRO B O 1 ATOM 3580 C CB . PRO C 1 90 ? 16.048 48.536 29.769 1.00 35.75 ? 90 PRO B CB 1 ATOM 3581 C CG . PRO C 1 90 ? 15.006 48.804 28.729 1.00 36.41 ? 90 PRO B CG 1 ATOM 3582 C CD . PRO C 1 90 ? 15.638 48.371 27.426 1.00 36.17 ? 90 PRO B CD 1 ATOM 3583 N N . ASP C 1 91 ? 14.912 45.713 29.605 1.00 34.86 ? 91 ASP B N 1 ATOM 3584 C CA . ASP C 1 91 ? 14.282 44.531 30.192 1.00 34.64 ? 91 ASP B CA 1 ATOM 3585 C C . ASP C 1 91 ? 14.938 43.219 29.726 1.00 34.29 ? 91 ASP B C 1 ATOM 3586 O O . ASP C 1 91 ? 15.446 42.457 30.562 1.00 33.84 ? 91 ASP B O 1 ATOM 3587 C CB . ASP C 1 91 ? 12.771 44.509 29.917 1.00 34.74 ? 91 ASP B CB 1 ATOM 3588 C CG . ASP C 1 91 ? 12.112 43.155 30.277 1.00 35.23 ? 91 ASP B CG 1 ATOM 3589 O OD1 . ASP C 1 91 ? 12.692 42.057 30.022 1.00 33.07 ? 91 ASP B OD1 1 ATOM 3590 O OD2 . ASP C 1 91 ? 10.975 43.208 30.803 1.00 36.20 ? 91 ASP B OD2 1 ATOM 3591 N N . ALA C 1 92 ? 14.921 42.990 28.402 1.00 33.67 ? 92 ALA B N 1 ATOM 3592 C CA . ALA C 1 92 ? 15.304 41.721 27.773 1.00 32.90 ? 92 ALA B CA 1 ATOM 3593 C C . ALA C 1 92 ? 14.887 40.563 28.657 1.00 32.39 ? 92 ALA B C 1 ATOM 3594 O O . ALA C 1 92 ? 13.737 40.171 28.641 1.00 32.19 ? 92 ALA B O 1 ATOM 3595 C CB . ALA C 1 92 ? 16.797 41.680 27.461 1.00 32.76 ? 92 ALA B CB 1 ATOM 3596 N N . ILE C 1 93 ? 15.829 40.067 29.454 1.00 32.13 ? 93 ILE B N 1 ATOM 3597 C CA . ILE C 1 93 ? 15.616 39.015 30.478 1.00 31.58 ? 93 ILE B CA 1 ATOM 3598 C C . ILE C 1 93 ? 14.173 38.729 30.921 1.00 31.29 ? 93 ILE B C 1 ATOM 3599 O O . ILE C 1 93 ? 13.685 37.617 30.727 1.00 31.23 ? 93 ILE B O 1 ATOM 3600 C CB . ILE C 1 93 ? 16.550 39.174 31.743 1.00 31.35 ? 93 ILE B CB 1 ATOM 3601 C CG1 . ILE C 1 93 ? 17.009 40.642 31.962 1.00 30.83 ? 93 ILE B CG1 1 ATOM 3602 C CG2 . ILE C 1 93 ? 17.718 38.175 31.669 1.00 30.87 ? 93 ILE B CG2 1 ATOM 3603 C CD1 . ILE C 1 93 ? 18.209 41.147 31.087 1.00 29.09 ? 93 ILE B CD1 1 ATOM 3604 N N . SER C 1 94 ? 13.483 39.711 31.494 1.00 30.83 ? 94 SER B N 1 ATOM 3605 C CA . SER C 1 94 ? 12.140 39.423 31.990 1.00 30.50 ? 94 SER B CA 1 ATOM 3606 C C . SER C 1 94 ? 11.103 39.430 30.856 1.00 29.93 ? 94 SER B C 1 ATOM 3607 O O . SER C 1 94 ? 10.005 38.905 31.007 1.00 29.90 ? 94 SER B O 1 ATOM 3608 C CB . SER C 1 94 ? 11.763 40.302 33.193 1.00 30.71 ? 94 SER B CB 1 ATOM 3609 O OG . SER C 1 94 ? 10.994 41.428 32.817 1.00 31.73 ? 94 SER B OG 1 ATOM 3610 N N . LEU C 1 95 ? 11.468 39.988 29.705 1.00 29.40 ? 95 LEU B N 1 ATOM 3611 C CA . LEU C 1 95 ? 10.770 39.646 28.457 1.00 28.70 ? 95 LEU B CA 1 ATOM 3612 C C . LEU C 1 95 ? 11.170 38.220 28.055 1.00 28.52 ? 95 LEU B C 1 ATOM 3613 O O . LEU C 1 95 ? 10.884 37.270 28.790 1.00 28.89 ? 95 LEU B O 1 ATOM 3614 C CB . LEU C 1 95 ? 11.106 40.636 27.353 1.00 28.18 ? 95 LEU B CB 1 ATOM 3615 C CG . LEU C 1 95 ? 10.383 41.957 27.510 1.00 27.78 ? 95 LEU B CG 1 ATOM 3616 C CD1 . LEU C 1 95 ? 10.883 42.931 26.478 1.00 28.21 ? 95 LEU B CD1 1 ATOM 3617 C CD2 . LEU C 1 95 ? 8.872 41.788 27.420 1.00 27.14 ? 95 LEU B CD2 1 ATOM 3618 N N . GLY C 1 96 ? 11.846 38.065 26.921 1.00 27.62 ? 96 GLY B N 1 ATOM 3619 C CA . GLY C 1 96 ? 12.401 36.778 26.569 1.00 26.84 ? 96 GLY B CA 1 ATOM 3620 C C . GLY C 1 96 ? 13.499 36.923 25.541 1.00 26.56 ? 96 GLY B C 1 ATOM 3621 O O . GLY C 1 96 ? 14.020 35.934 25.014 1.00 27.20 ? 96 GLY B O 1 ATOM 3622 N N . LEU C 1 97 ? 13.883 38.153 25.262 1.00 25.56 ? 97 LEU B N 1 ATOM 3623 C CA . LEU C 1 97 ? 14.720 38.395 24.117 1.00 24.80 ? 97 LEU B CA 1 ATOM 3624 C C . LEU C 1 97 ? 16.176 38.377 24.487 1.00 24.71 ? 97 LEU B C 1 ATOM 3625 O O . LEU C 1 97 ? 16.608 39.139 25.350 1.00 24.85 ? 97 LEU B O 1 ATOM 3626 C CB . LEU C 1 97 ? 14.355 39.737 23.526 1.00 24.80 ? 97 LEU B CB 1 ATOM 3627 C CG . LEU C 1 97 ? 12.942 40.201 23.841 1.00 23.91 ? 97 LEU B CG 1 ATOM 3628 C CD1 . LEU C 1 97 ? 12.935 41.703 23.702 1.00 23.16 ? 97 LEU B CD1 1 ATOM 3629 C CD2 . LEU C 1 97 ? 11.883 39.513 22.952 1.00 22.78 ? 97 LEU B CD2 1 ATOM 3630 N N . GLY C 1 98 ? 16.937 37.525 23.816 1.00 24.65 ? 98 GLY B N 1 ATOM 3631 C CA . GLY C 1 98 ? 18.360 37.352 24.131 1.00 25.48 ? 98 GLY B CA 1 ATOM 3632 C C . GLY C 1 98 ? 19.239 37.133 22.919 1.00 25.72 ? 98 GLY B C 1 ATOM 3633 O O . GLY C 1 98 ? 18.884 37.567 21.833 1.00 26.22 ? 98 GLY B O 1 ATOM 3634 N N . LYS C 1 99 ? 20.382 36.472 23.101 1.00 25.77 ? 99 LYS B N 1 ATOM 3635 C CA . LYS C 1 99 ? 21.288 36.172 21.987 1.00 26.43 ? 99 LYS B CA 1 ATOM 3636 C C . LYS C 1 99 ? 20.748 35.046 21.082 1.00 27.00 ? 99 LYS B C 1 ATOM 3637 O O . LYS C 1 99 ? 21.463 34.090 20.755 1.00 27.98 ? 99 LYS B O 1 ATOM 3638 C CB . LYS C 1 99 ? 22.704 35.815 22.486 1.00 26.31 ? 99 LYS B CB 1 ATOM 3639 C CG . LYS C 1 99 ? 23.747 36.934 22.418 1.00 26.50 ? 99 LYS B CG 1 ATOM 3640 C CD . LYS C 1 99 ? 24.974 36.575 23.287 1.00 26.77 ? 99 LYS B CD 1 ATOM 3641 C CE . LYS C 1 99 ? 26.114 37.617 23.215 1.00 26.16 ? 99 LYS B CE 1 ATOM 3642 N NZ . LYS C 1 99 ? 25.909 38.788 24.107 1.00 25.61 ? 99 LYS B NZ 1 ATOM 3643 N N . HIS C 1 100 ? 19.509 35.159 20.641 1.00 26.80 ? 100 HIS B N 1 ATOM 3644 C CA . HIS C 1 100 ? 18.926 34.080 19.901 1.00 26.98 ? 100 HIS B CA 1 ATOM 3645 C C . HIS C 1 100 ? 17.973 34.597 18.820 1.00 27.45 ? 100 HIS B C 1 ATOM 3646 O O . HIS C 1 100 ? 17.851 35.796 18.635 1.00 27.55 ? 100 HIS B O 1 ATOM 3647 C CB . HIS C 1 100 ? 18.196 33.202 20.912 1.00 26.95 ? 100 HIS B CB 1 ATOM 3648 C CG . HIS C 1 100 ? 16.996 33.855 21.508 1.00 26.35 ? 100 HIS B CG 1 ATOM 3649 N ND1 . HIS C 1 100 ? 17.073 34.704 22.584 1.00 26.88 ? 100 HIS B ND1 1 ATOM 3650 C CD2 . HIS C 1 100 ? 15.691 33.817 21.154 1.00 26.33 ? 100 HIS B CD2 1 ATOM 3651 C CE1 . HIS C 1 100 ? 15.862 35.130 22.895 1.00 26.87 ? 100 HIS B CE1 1 ATOM 3652 N NE2 . HIS C 1 100 ? 15.004 34.609 22.039 1.00 25.57 ? 100 HIS B NE2 1 ATOM 3653 N N . ASN C 1 101 ? 17.280 33.707 18.113 1.00 28.01 ? 101 ASN B N 1 ATOM 3654 C CA . ASN C 1 101 ? 16.211 34.148 17.201 1.00 28.53 ? 101 ASN B CA 1 ATOM 3655 C C . ASN C 1 101 ? 14.946 33.309 17.302 1.00 28.93 ? 101 ASN B C 1 ATOM 3656 O O . ASN C 1 101 ? 14.467 32.743 16.314 1.00 28.96 ? 101 ASN B O 1 ATOM 3657 C CB . ASN C 1 101 ? 16.686 34.224 15.743 1.00 28.49 ? 101 ASN B CB 1 ATOM 3658 C CG . ASN C 1 101 ? 17.048 32.879 15.189 1.00 27.71 ? 101 ASN B CG 1 ATOM 3659 O OD1 . ASN C 1 101 ? 17.525 32.026 15.924 1.00 29.17 ? 101 ASN B OD1 1 ATOM 3660 N ND2 . ASN C 1 101 ? 16.824 32.672 13.899 1.00 26.46 ? 101 ASN B ND2 1 ATOM 3661 N N . TYR C 1 102 ? 14.418 33.235 18.511 1.00 29.37 ? 102 TYR B N 1 ATOM 3662 C CA . TYR C 1 102 ? 13.156 32.570 18.757 1.00 29.89 ? 102 TYR B CA 1 ATOM 3663 C C . TYR C 1 102 ? 12.076 33.595 19.046 1.00 30.63 ? 102 TYR B C 1 ATOM 3664 O O . TYR C 1 102 ? 12.258 34.529 19.828 1.00 30.94 ? 102 TYR B O 1 ATOM 3665 C CB . TYR C 1 102 ? 13.280 31.601 19.922 1.00 29.38 ? 102 TYR B CB 1 ATOM 3666 C CG . TYR C 1 102 ? 14.565 30.826 19.925 1.00 29.35 ? 102 TYR B CG 1 ATOM 3667 C CD1 . TYR C 1 102 ? 14.923 30.051 18.835 1.00 29.65 ? 102 TYR B CD1 1 ATOM 3668 C CD2 . TYR C 1 102 ? 15.417 30.842 21.035 1.00 29.31 ? 102 TYR B CD2 1 ATOM 3669 C CE1 . TYR C 1 102 ? 16.081 29.319 18.843 1.00 29.46 ? 102 TYR B CE1 1 ATOM 3670 C CE2 . TYR C 1 102 ? 16.580 30.115 21.053 1.00 28.23 ? 102 TYR B CE2 1 ATOM 3671 C CZ . TYR C 1 102 ? 16.901 29.360 19.946 1.00 29.19 ? 102 TYR B CZ 1 ATOM 3672 O OH . TYR C 1 102 ? 18.050 28.636 19.908 1.00 31.01 ? 102 TYR B OH 1 ATOM 3673 N N . CYS C 1 103 ? 10.936 33.408 18.422 1.00 31.58 ? 103 CYS B N 1 ATOM 3674 C CA . CYS C 1 103 ? 9.866 34.371 18.532 1.00 33.21 ? 103 CYS B CA 1 ATOM 3675 C C . CYS C 1 103 ? 9.314 34.484 19.936 1.00 32.93 ? 103 CYS B C 1 ATOM 3676 O O . CYS C 1 103 ? 9.336 33.531 20.714 1.00 32.84 ? 103 CYS B O 1 ATOM 3677 C CB . CYS C 1 103 ? 8.754 33.991 17.580 1.00 33.85 ? 103 CYS B CB 1 ATOM 3678 S SG . CYS C 1 103 ? 8.833 32.244 17.298 1.00 38.36 ? 103 CYS B SG 1 ATOM 3679 N N . ARG C 1 104 ? 8.822 35.680 20.232 1.00 32.78 ? 104 ARG B N 1 ATOM 3680 C CA . ARG C 1 104 ? 8.239 36.006 21.501 1.00 32.48 ? 104 ARG B CA 1 ATOM 3681 C C . ARG C 1 104 ? 7.146 37.022 21.215 1.00 32.08 ? 104 ARG B C 1 ATOM 3682 O O . ARG C 1 104 ? 7.215 37.764 20.238 1.00 31.85 ? 104 ARG B O 1 ATOM 3683 C CB . ARG C 1 104 ? 9.292 36.638 22.417 1.00 32.82 ? 104 ARG B CB 1 ATOM 3684 C CG . ARG C 1 104 ? 10.625 35.892 22.528 1.00 33.59 ? 104 ARG B CG 1 ATOM 3685 C CD . ARG C 1 104 ? 10.655 34.959 23.737 1.00 34.87 ? 104 ARG B CD 1 ATOM 3686 N NE . ARG C 1 104 ? 11.850 34.113 23.753 1.00 35.62 ? 104 ARG B NE 1 ATOM 3687 C CZ . ARG C 1 104 ? 11.893 32.863 23.294 1.00 36.53 ? 104 ARG B CZ 1 ATOM 3688 N NH1 . ARG C 1 104 ? 10.818 32.286 22.775 1.00 37.16 ? 104 ARG B NH1 1 ATOM 3689 N NH2 . ARG C 1 104 ? 13.014 32.178 23.351 1.00 36.97 ? 104 ARG B NH2 1 ATOM 3690 N N . ASN C 1 105 ? 6.140 37.036 22.082 1.00 31.82 ? 105 ASN B N 1 ATOM 3691 C CA . ASN C 1 105 ? 5.042 37.997 22.076 1.00 31.28 ? 105 ASN B CA 1 ATOM 3692 C C . ASN C 1 105 ? 5.248 38.925 23.273 1.00 31.05 ? 105 ASN B C 1 ATOM 3693 O O . ASN C 1 105 ? 4.456 38.908 24.212 1.00 30.70 ? 105 ASN B O 1 ATOM 3694 C CB . ASN C 1 105 ? 3.710 37.219 22.173 1.00 31.26 ? 105 ASN B CB 1 ATOM 3695 C CG . ASN C 1 105 ? 2.462 38.115 22.262 1.00 31.26 ? 105 ASN B CG 1 ATOM 3696 O OD1 . ASN C 1 105 ? 2.522 39.340 22.124 1.00 31.63 ? 105 ASN B OD1 1 ATOM 3697 N ND2 . ASN C 1 105 ? 1.317 37.482 22.495 1.00 29.98 ? 105 ASN B ND2 1 ATOM 3698 N N . PRO C 1 106 ? 6.331 39.731 23.254 1.00 31.18 ? 106 PRO B N 1 ATOM 3699 C CA . PRO C 1 106 ? 6.642 40.582 24.407 1.00 31.36 ? 106 PRO B CA 1 ATOM 3700 C C . PRO C 1 106 ? 5.796 41.846 24.405 1.00 31.45 ? 106 PRO B C 1 ATOM 3701 O O . PRO C 1 106 ? 5.559 42.447 25.458 1.00 31.40 ? 106 PRO B O 1 ATOM 3702 C CB . PRO C 1 106 ? 8.100 40.969 24.154 1.00 31.42 ? 106 PRO B CB 1 ATOM 3703 C CG . PRO C 1 106 ? 8.197 41.072 22.677 1.00 31.29 ? 106 PRO B CG 1 ATOM 3704 C CD . PRO C 1 106 ? 7.241 40.012 22.125 1.00 31.19 ? 106 PRO B CD 1 ATOM 3705 N N . ASP C 1 107 ? 5.325 42.193 23.203 1.00 31.52 ? 107 ASP B N 1 ATOM 3706 C CA . ASP C 1 107 ? 4.821 43.511 22.843 1.00 31.07 ? 107 ASP B CA 1 ATOM 3707 C C . ASP C 1 107 ? 3.331 43.669 23.073 1.00 30.43 ? 107 ASP B C 1 ATOM 3708 O O . ASP C 1 107 ? 2.684 44.479 22.423 1.00 30.17 ? 107 ASP B O 1 ATOM 3709 C CB . ASP C 1 107 ? 5.147 43.769 21.371 1.00 31.16 ? 107 ASP B CB 1 ATOM 3710 C CG . ASP C 1 107 ? 5.193 45.238 21.037 1.00 31.55 ? 107 ASP B CG 1 ATOM 3711 O OD1 . ASP C 1 107 ? 4.821 46.069 21.897 1.00 32.01 ? 107 ASP B OD1 1 ATOM 3712 O OD2 . ASP C 1 107 ? 5.613 45.563 19.908 1.00 31.66 ? 107 ASP B OD2 1 ATOM 3713 N N . ASN C 1 108 ? 2.799 42.897 24.011 1.00 30.16 ? 108 ASN B N 1 ATOM 3714 C CA . ASN C 1 108 ? 1.395 42.986 24.405 1.00 30.28 ? 108 ASN B CA 1 ATOM 3715 C C . ASN C 1 108 ? 0.450 42.765 23.201 1.00 29.95 ? 108 ASN B C 1 ATOM 3716 O O . ASN C 1 108 ? -0.539 43.475 23.008 1.00 29.48 ? 108 ASN B O 1 ATOM 3717 C CB . ASN C 1 108 ? 1.112 44.328 25.115 1.00 30.68 ? 108 ASN B CB 1 ATOM 3718 C CG . ASN C 1 108 ? 2.377 44.983 25.740 1.00 31.38 ? 108 ASN B CG 1 ATOM 3719 O OD1 . ASN C 1 108 ? 3.471 44.399 25.783 1.00 31.14 ? 108 ASN B OD1 1 ATOM 3720 N ND2 . ASN C 1 108 ? 2.207 46.218 26.222 1.00 31.63 ? 108 ASN B ND2 1 ATOM 3721 N N . GLN C 1 109 ? 0.775 41.751 22.406 1.00 29.85 ? 109 GLN B N 1 ATOM 3722 C CA . GLN C 1 109 ? 0.166 41.538 21.106 1.00 29.55 ? 109 GLN B CA 1 ATOM 3723 C C . GLN C 1 109 ? -0.502 40.184 21.030 1.00 29.44 ? 109 GLN B C 1 ATOM 3724 O O . GLN C 1 109 ? -0.455 39.415 21.977 1.00 29.66 ? 109 GLN B O 1 ATOM 3725 C CB . GLN C 1 109 ? 1.252 41.593 20.050 1.00 29.69 ? 109 GLN B CB 1 ATOM 3726 C CG . GLN C 1 109 ? 0.794 42.050 18.695 1.00 29.53 ? 109 GLN B CG 1 ATOM 3727 C CD . GLN C 1 109 ? 1.893 41.911 17.676 1.00 29.51 ? 109 GLN B CD 1 ATOM 3728 O OE1 . GLN C 1 109 ? 2.378 40.805 17.412 1.00 29.17 ? 109 GLN B OE1 1 ATOM 3729 N NE2 . GLN C 1 109 ? 2.308 43.034 17.103 1.00 28.96 ? 109 GLN B NE2 1 ATOM 3730 N N . LYS C 1 110 ? -1.086 39.895 19.873 1.00 29.34 ? 110 LYS B N 1 ATOM 3731 C CA . LYS C 1 110 ? -1.961 38.741 19.667 1.00 29.12 ? 110 LYS B CA 1 ATOM 3732 C C . LYS C 1 110 ? -1.282 37.386 19.800 1.00 29.18 ? 110 LYS B C 1 ATOM 3733 O O . LYS C 1 110 ? -1.895 36.450 20.306 1.00 29.25 ? 110 LYS B O 1 ATOM 3734 C CB . LYS C 1 110 ? -2.654 38.838 18.298 1.00 29.06 ? 110 LYS B CB 1 ATOM 3735 C CG . LYS C 1 110 ? -4.100 39.282 18.342 1.00 27.95 ? 110 LYS B CG 1 ATOM 3736 C CD . LYS C 1 110 ? -4.985 38.150 18.825 1.00 27.13 ? 110 LYS B CD 1 ATOM 3737 C CE . LYS C 1 110 ? -6.437 38.415 18.514 1.00 26.55 ? 110 LYS B CE 1 ATOM 3738 N NZ . LYS C 1 110 ? -7.227 37.174 18.677 1.00 26.63 ? 110 LYS B NZ 1 ATOM 3739 N N . ARG C 1 111 ? -0.035 37.283 19.341 1.00 29.22 ? 111 ARG B N 1 ATOM 3740 C CA . ARG C 1 111 ? 0.716 36.022 19.380 1.00 29.50 ? 111 ARG B CA 1 ATOM 3741 C C . ARG C 1 111 ? 2.186 36.201 18.958 1.00 29.54 ? 111 ARG B C 1 ATOM 3742 O O . ARG C 1 111 ? 2.486 37.073 18.139 1.00 29.57 ? 111 ARG B O 1 ATOM 3743 C CB . ARG C 1 111 ? 0.045 34.992 18.478 1.00 29.59 ? 111 ARG B CB 1 ATOM 3744 C CG . ARG C 1 111 ? -0.023 35.405 17.027 1.00 30.33 ? 111 ARG B CG 1 ATOM 3745 C CD . ARG C 1 111 ? 0.328 34.233 16.131 1.00 31.73 ? 111 ARG B CD 1 ATOM 3746 N NE . ARG C 1 111 ? -0.830 33.382 15.861 1.00 32.47 ? 111 ARG B NE 1 ATOM 3747 C CZ . ARG C 1 111 ? -0.759 32.122 15.433 1.00 32.74 ? 111 ARG B CZ 1 ATOM 3748 N NH1 . ARG C 1 111 ? 0.420 31.533 15.233 1.00 32.63 ? 111 ARG B NH1 1 ATOM 3749 N NH2 . ARG C 1 111 ? -1.877 31.442 15.216 1.00 32.79 ? 111 ARG B NH2 1 ATOM 3750 N N . PRO C 1 112 ? 3.102 35.351 19.471 1.00 29.67 ? 112 PRO B N 1 ATOM 3751 C CA . PRO C 1 112 ? 4.522 35.637 19.240 1.00 29.91 ? 112 PRO B CA 1 ATOM 3752 C C . PRO C 1 112 ? 4.845 35.848 17.773 1.00 29.86 ? 112 PRO B C 1 ATOM 3753 O O . PRO C 1 112 ? 4.174 35.326 16.886 1.00 30.07 ? 112 PRO B O 1 ATOM 3754 C CB . PRO C 1 112 ? 5.258 34.397 19.788 1.00 29.75 ? 112 PRO B CB 1 ATOM 3755 C CG . PRO C 1 112 ? 4.262 33.328 19.763 1.00 30.17 ? 112 PRO B CG 1 ATOM 3756 C CD . PRO C 1 112 ? 2.910 33.989 19.996 1.00 30.05 ? 112 PRO B CD 1 ATOM 3757 N N . TRP C 1 113 ? 5.898 36.605 17.544 1.00 29.55 ? 113 TRP B N 1 ATOM 3758 C CA . TRP C 1 113 ? 6.178 37.151 16.264 1.00 29.16 ? 113 TRP B CA 1 ATOM 3759 C C . TRP C 1 113 ? 7.617 37.530 16.372 1.00 29.16 ? 113 TRP B C 1 ATOM 3760 O O . TRP C 1 113 ? 8.160 37.578 17.474 1.00 29.34 ? 113 TRP B O 1 ATOM 3761 C CB . TRP C 1 113 ? 5.355 38.410 16.111 1.00 29.28 ? 113 TRP B CB 1 ATOM 3762 C CG . TRP C 1 113 ? 5.554 39.353 17.253 1.00 29.46 ? 113 TRP B CG 1 ATOM 3763 C CD1 . TRP C 1 113 ? 4.747 39.510 18.349 1.00 29.64 ? 113 TRP B CD1 1 ATOM 3764 C CD2 . TRP C 1 113 ? 6.640 40.260 17.423 1.00 29.02 ? 113 TRP B CD2 1 ATOM 3765 N NE1 . TRP C 1 113 ? 5.260 40.476 19.181 1.00 29.12 ? 113 TRP B NE1 1 ATOM 3766 C CE2 . TRP C 1 113 ? 6.427 40.945 18.637 1.00 29.19 ? 113 TRP B CE2 1 ATOM 3767 C CE3 . TRP C 1 113 ? 7.768 40.572 16.658 1.00 28.71 ? 113 TRP B CE3 1 ATOM 3768 C CZ2 . TRP C 1 113 ? 7.307 41.915 19.104 1.00 29.79 ? 113 TRP B CZ2 1 ATOM 3769 C CZ3 . TRP C 1 113 ? 8.645 41.525 17.125 1.00 29.13 ? 113 TRP B CZ3 1 ATOM 3770 C CH2 . TRP C 1 113 ? 8.411 42.188 18.336 1.00 29.87 ? 113 TRP B CH2 1 ATOM 3771 N N . CYS C 1 114 ? 8.244 37.810 15.244 1.00 28.95 ? 114 CYS B N 1 ATOM 3772 C CA . CYS C 1 114 ? 9.655 38.146 15.246 1.00 28.94 ? 114 CYS B CA 1 ATOM 3773 C C . CYS C 1 114 ? 9.861 39.044 14.066 1.00 28.47 ? 114 CYS B C 1 ATOM 3774 O O . CYS C 1 114 ? 9.018 39.106 13.182 1.00 28.09 ? 114 CYS B O 1 ATOM 3775 C CB . CYS C 1 114 ? 10.525 36.889 15.123 1.00 28.87 ? 114 CYS B CB 1 ATOM 3776 S SG . CYS C 1 114 ? 10.200 35.990 13.562 1.00 31.29 ? 114 CYS B SG 1 ATOM 3777 N N . TYR C 1 115 ? 10.979 39.749 14.067 1.00 28.64 ? 115 TYR B N 1 ATOM 3778 C CA . TYR C 1 115 ? 11.358 40.551 12.935 1.00 29.17 ? 115 TYR B CA 1 ATOM 3779 C C . TYR C 1 115 ? 11.868 39.631 11.837 1.00 29.99 ? 115 TYR B C 1 ATOM 3780 O O . TYR C 1 115 ? 12.633 38.682 12.098 1.00 30.34 ? 115 TYR B O 1 ATOM 3781 C CB . TYR C 1 115 ? 12.401 41.574 13.335 1.00 28.77 ? 115 TYR B CB 1 ATOM 3782 C CG . TYR C 1 115 ? 11.904 42.513 14.407 1.00 28.86 ? 115 TYR B CG 1 ATOM 3783 C CD1 . TYR C 1 115 ? 11.006 43.547 14.106 1.00 29.00 ? 115 TYR B CD1 1 ATOM 3784 C CD2 . TYR C 1 115 ? 12.313 42.362 15.729 1.00 28.04 ? 115 TYR B CD2 1 ATOM 3785 C CE1 . TYR C 1 115 ? 10.544 44.408 15.103 1.00 28.40 ? 115 TYR B CE1 1 ATOM 3786 C CE2 . TYR C 1 115 ? 11.866 43.210 16.721 1.00 27.62 ? 115 TYR B CE2 1 ATOM 3787 C CZ . TYR C 1 115 ? 10.984 44.228 16.408 1.00 28.06 ? 115 TYR B CZ 1 ATOM 3788 O OH . TYR C 1 115 ? 10.558 45.066 17.409 1.00 27.78 ? 115 TYR B OH 1 ATOM 3789 N N . VAL C 1 116 ? 11.398 39.895 10.615 1.00 30.46 ? 116 VAL B N 1 ATOM 3790 C CA . VAL C 1 116 ? 11.726 39.076 9.452 1.00 30.34 ? 116 VAL B CA 1 ATOM 3791 C C . VAL C 1 116 ? 12.301 39.956 8.381 1.00 30.51 ? 116 VAL B C 1 ATOM 3792 O O . VAL C 1 116 ? 11.922 41.128 8.285 1.00 30.52 ? 116 VAL B O 1 ATOM 3793 C CB . VAL C 1 116 ? 10.510 38.362 8.909 1.00 30.15 ? 116 VAL B CB 1 ATOM 3794 C CG1 . VAL C 1 116 ? 10.900 37.563 7.697 1.00 29.73 ? 116 VAL B CG1 1 ATOM 3795 C CG2 . VAL C 1 116 ? 9.956 37.439 9.970 1.00 30.55 ? 116 VAL B CG2 1 ATOM 3796 N N . GLN C 1 117 ? 13.214 39.387 7.587 1.00 30.62 ? 117 GLN B N 1 ATOM 3797 C CA . GLN C 1 117 ? 13.995 40.158 6.625 1.00 30.93 ? 117 GLN B CA 1 ATOM 3798 C C . GLN C 1 117 ? 13.353 40.212 5.244 1.00 31.14 ? 117 GLN B C 1 ATOM 3799 O O . GLN C 1 117 ? 13.879 39.585 4.316 1.00 32.05 ? 117 GLN B O 1 ATOM 3800 C CB . GLN C 1 117 ? 15.405 39.573 6.492 1.00 30.77 ? 117 GLN B CB 1 ATOM 3801 C CG . GLN C 1 117 ? 16.307 40.357 5.543 1.00 31.59 ? 117 GLN B CG 1 ATOM 3802 C CD . GLN C 1 117 ? 16.206 41.857 5.776 1.00 33.76 ? 117 GLN B CD 1 ATOM 3803 O OE1 . GLN C 1 117 ? 16.630 42.364 6.823 1.00 36.05 ? 117 GLN B OE1 1 ATOM 3804 N NE2 . GLN C 1 117 ? 15.632 42.572 4.814 1.00 32.56 ? 117 GLN B NE2 1 ATOM 3805 N N . ILE C 1 118 ? 12.245 40.947 5.075 1.00 30.47 ? 118 ILE B N 1 ATOM 3806 C CA . ILE C 1 118 ? 11.556 40.928 3.770 1.00 29.44 ? 118 ILE B CA 1 ATOM 3807 C C . ILE C 1 118 ? 12.242 41.799 2.703 1.00 29.14 ? 118 ILE B C 1 ATOM 3808 O O . ILE C 1 118 ? 11.848 42.936 2.424 1.00 28.63 ? 118 ILE B O 1 ATOM 3809 C CB . ILE C 1 118 ? 9.975 40.973 3.857 1.00 29.31 ? 118 ILE B CB 1 ATOM 3810 C CG1 . ILE C 1 118 ? 9.350 41.628 2.607 1.00 30.26 ? 118 ILE B CG1 1 ATOM 3811 C CG2 . ILE C 1 118 ? 9.498 41.594 5.143 1.00 27.99 ? 118 ILE B CG2 1 ATOM 3812 C CD1 . ILE C 1 118 ? 8.038 40.953 2.072 1.00 30.16 ? 118 ILE B CD1 1 ATOM 3813 N N . GLY C 1 119 ? 13.315 41.239 2.151 1.00 28.89 ? 119 GLY B N 1 ATOM 3814 C CA . GLY C 1 119 ? 14.113 41.888 1.120 1.00 29.01 ? 119 GLY B CA 1 ATOM 3815 C C . GLY C 1 119 ? 14.995 43.053 1.549 1.00 28.91 ? 119 GLY B C 1 ATOM 3816 O O . GLY C 1 119 ? 16.231 42.941 1.521 1.00 28.90 ? 119 GLY B O 1 ATOM 3817 N N . LEU C 1 120 ? 14.370 44.175 1.920 1.00 28.61 ? 120 LEU B N 1 ATOM 3818 C CA . LEU C 1 120 ? 15.110 45.405 2.219 1.00 28.45 ? 120 LEU B CA 1 ATOM 3819 C C . LEU C 1 120 ? 14.652 46.190 3.450 1.00 28.31 ? 120 LEU B C 1 ATOM 3820 O O . LEU C 1 120 ? 15.297 47.155 3.843 1.00 28.03 ? 120 LEU B O 1 ATOM 3821 C CB . LEU C 1 120 ? 15.134 46.319 0.999 1.00 28.68 ? 120 LEU B CB 1 ATOM 3822 C CG . LEU C 1 120 ? 16.166 45.978 -0.077 1.00 29.12 ? 120 LEU B CG 1 ATOM 3823 C CD1 . LEU C 1 120 ? 15.998 46.923 -1.270 1.00 29.30 ? 120 LEU B CD1 1 ATOM 3824 C CD2 . LEU C 1 120 ? 17.605 45.997 0.465 1.00 28.63 ? 120 LEU B CD2 1 ATOM 3825 N N . ARG C 1 121 ? 13.538 45.778 4.044 1.00 28.36 ? 121 ARG B N 1 ATOM 3826 C CA . ARG C 1 121 ? 13.123 46.270 5.353 1.00 28.20 ? 121 ARG B CA 1 ATOM 3827 C C . ARG C 1 121 ? 12.870 45.111 6.316 1.00 28.11 ? 121 ARG B C 1 ATOM 3828 O O . ARG C 1 121 ? 13.103 43.947 5.979 1.00 27.71 ? 121 ARG B O 1 ATOM 3829 C CB . ARG C 1 121 ? 11.883 47.147 5.220 1.00 28.23 ? 121 ARG B CB 1 ATOM 3830 C CG . ARG C 1 121 ? 12.160 48.636 5.163 1.00 28.47 ? 121 ARG B CG 1 ATOM 3831 C CD . ARG C 1 121 ? 10.866 49.425 5.196 1.00 28.44 ? 121 ARG B CD 1 ATOM 3832 N NE . ARG C 1 121 ? 10.234 49.435 3.878 1.00 29.70 ? 121 ARG B NE 1 ATOM 3833 C CZ . ARG C 1 121 ? 8.936 49.631 3.653 1.00 29.89 ? 121 ARG B CZ 1 ATOM 3834 N NH1 . ARG C 1 121 ? 8.103 49.817 4.669 1.00 29.87 ? 121 ARG B NH1 1 ATOM 3835 N NH2 . ARG C 1 121 ? 8.469 49.637 2.405 1.00 29.73 ? 121 ARG B NH2 1 ATOM 3836 N N . GLN C 1 122 ? 12.419 45.430 7.522 1.00 28.53 ? 122 GLN B N 1 ATOM 3837 C CA . GLN C 1 122 ? 12.151 44.397 8.525 1.00 29.28 ? 122 GLN B CA 1 ATOM 3838 C C . GLN C 1 122 ? 10.779 44.550 9.118 1.00 29.56 ? 122 GLN B C 1 ATOM 3839 O O . GLN C 1 122 ? 10.537 45.454 9.906 1.00 29.80 ? 122 GLN B O 1 ATOM 3840 C CB . GLN C 1 122 ? 13.170 44.419 9.666 1.00 29.16 ? 122 GLN B CB 1 ATOM 3841 C CG . GLN C 1 122 ? 14.577 44.097 9.273 1.00 29.70 ? 122 GLN B CG 1 ATOM 3842 C CD . GLN C 1 122 ? 15.237 45.289 8.681 1.00 31.18 ? 122 GLN B CD 1 ATOM 3843 O OE1 . GLN C 1 122 ? 15.743 45.240 7.561 1.00 32.58 ? 122 GLN B OE1 1 ATOM 3844 N NE2 . GLN C 1 122 ? 15.188 46.401 9.402 1.00 32.09 ? 122 GLN B NE2 1 ATOM 3845 N N . PHE C 1 123 ? 9.885 43.652 8.754 1.00 29.98 ? 123 PHE B N 1 ATOM 3846 C CA . PHE C 1 123 ? 8.536 43.706 9.261 1.00 30.57 ? 123 PHE B CA 1 ATOM 3847 C C . PHE C 1 123 ? 8.390 42.706 10.389 1.00 31.17 ? 123 PHE B C 1 ATOM 3848 O O . PHE C 1 123 ? 9.202 41.785 10.550 1.00 31.21 ? 123 PHE B O 1 ATOM 3849 C CB . PHE C 1 123 ? 7.535 43.380 8.161 1.00 30.46 ? 123 PHE B CB 1 ATOM 3850 C CG . PHE C 1 123 ? 7.705 44.200 6.926 1.00 30.71 ? 123 PHE B CG 1 ATOM 3851 C CD1 . PHE C 1 123 ? 8.939 44.291 6.295 1.00 30.44 ? 123 PHE B CD1 1 ATOM 3852 C CD2 . PHE C 1 123 ? 6.618 44.866 6.375 1.00 31.64 ? 123 PHE B CD2 1 ATOM 3853 C CE1 . PHE C 1 123 ? 9.094 45.041 5.156 1.00 31.28 ? 123 PHE B CE1 1 ATOM 3854 C CE2 . PHE C 1 123 ? 6.758 45.631 5.231 1.00 31.63 ? 123 PHE B CE2 1 ATOM 3855 C CZ . PHE C 1 123 ? 8.002 45.722 4.617 1.00 31.94 ? 123 PHE B CZ 1 ATOM 3856 N N . VAL C 1 124 ? 7.332 42.905 11.157 1.00 31.74 ? 124 VAL B N 1 ATOM 3857 C CA . VAL C 1 124 ? 6.968 42.027 12.235 1.00 32.42 ? 124 VAL B CA 1 ATOM 3858 C C . VAL C 1 124 ? 6.135 40.900 11.664 1.00 32.96 ? 124 VAL B C 1 ATOM 3859 O O . VAL C 1 124 ? 5.002 41.111 11.257 1.00 33.12 ? 124 VAL B O 1 ATOM 3860 C CB . VAL C 1 124 ? 6.212 42.825 13.327 1.00 32.31 ? 124 VAL B CB 1 ATOM 3861 C CG1 . VAL C 1 124 ? 5.177 41.978 14.073 1.00 32.21 ? 124 VAL B CG1 1 ATOM 3862 C CG2 . VAL C 1 124 ? 7.215 43.430 14.291 1.00 32.84 ? 124 VAL B CG2 1 ATOM 3863 N N . GLN C 1 125 ? 6.705 39.704 11.615 1.00 33.91 ? 125 GLN B N 1 ATOM 3864 C CA . GLN C 1 125 ? 5.954 38.546 11.153 1.00 35.13 ? 125 GLN B CA 1 ATOM 3865 C C . GLN C 1 125 ? 5.509 37.642 12.301 1.00 35.79 ? 125 GLN B C 1 ATOM 3866 O O . GLN C 1 125 ? 6.190 37.560 13.323 1.00 35.92 ? 125 GLN B O 1 ATOM 3867 C CB . GLN C 1 125 ? 6.767 37.755 10.128 1.00 35.22 ? 125 GLN B CB 1 ATOM 3868 C CG . GLN C 1 125 ? 6.964 38.462 8.791 1.00 35.75 ? 125 GLN B CG 1 ATOM 3869 C CD . GLN C 1 125 ? 5.668 38.648 8.022 1.00 36.92 ? 125 GLN B CD 1 ATOM 3870 O OE1 . GLN C 1 125 ? 5.044 37.680 7.575 1.00 37.59 ? 125 GLN B OE1 1 ATOM 3871 N NE2 . GLN C 1 125 ? 5.257 39.904 7.860 1.00 37.04 ? 125 GLN B NE2 1 ATOM 3872 N N . GLU C 1 126 ? 4.364 36.981 12.126 1.00 36.75 ? 126 GLU B N 1 ATOM 3873 C CA . GLU C 1 126 ? 3.875 35.994 13.084 1.00 37.89 ? 126 GLU B CA 1 ATOM 3874 C C . GLU C 1 126 ? 4.644 34.713 12.924 1.00 38.57 ? 126 GLU B C 1 ATOM 3875 O O . GLU C 1 126 ? 5.028 34.350 11.814 1.00 38.27 ? 126 GLU B O 1 ATOM 3876 C CB . GLU C 1 126 ? 2.399 35.700 12.888 1.00 37.88 ? 126 GLU B CB 1 ATOM 3877 C CG . GLU C 1 126 ? 1.481 36.642 13.614 1.00 39.26 ? 126 GLU B CG 1 ATOM 3878 C CD . GLU C 1 126 ? 0.038 36.463 13.183 1.00 42.32 ? 126 GLU B CD 1 ATOM 3879 O OE1 . GLU C 1 126 ? -0.225 36.379 11.954 1.00 43.56 ? 126 GLU B OE1 1 ATOM 3880 O OE2 . GLU C 1 126 ? -0.845 36.407 14.069 1.00 43.65 ? 126 GLU B OE2 1 ATOM 3881 N N . CYS C 1 127 ? 4.839 34.027 14.047 1.00 39.80 ? 127 CYS B N 1 ATOM 3882 C CA . CYS C 1 127 ? 5.754 32.903 14.126 1.00 41.10 ? 127 CYS B CA 1 ATOM 3883 C C . CYS C 1 127 ? 5.096 31.554 13.868 1.00 41.79 ? 127 CYS B C 1 ATOM 3884 O O . CYS C 1 127 ? 3.891 31.405 14.034 1.00 42.14 ? 127 CYS B O 1 ATOM 3885 C CB . CYS C 1 127 ? 6.450 32.893 15.480 1.00 40.91 ? 127 CYS B CB 1 ATOM 3886 S SG . CYS C 1 127 ? 8.028 31.987 15.430 1.00 43.03 ? 127 CYS B SG 1 ATOM 3887 N N . MET C 1 128 ? 5.912 30.585 13.454 1.00 42.85 ? 128 MET B N 1 ATOM 3888 C CA . MET C 1 128 ? 5.497 29.200 13.192 1.00 43.64 ? 128 MET B CA 1 ATOM 3889 C C . MET C 1 128 ? 4.592 28.667 14.315 1.00 43.92 ? 128 MET B C 1 ATOM 3890 O O . MET C 1 128 ? 3.378 28.826 14.235 1.00 43.71 ? 128 MET B O 1 ATOM 3891 C CB . MET C 1 128 ? 6.748 28.316 12.979 1.00 43.75 ? 128 MET B CB 1 ATOM 3892 C CG . MET C 1 128 ? 6.583 27.028 12.152 1.00 45.05 ? 128 MET B CG 1 ATOM 3893 S SD . MET C 1 128 ? 5.731 27.107 10.533 1.00 48.00 ? 128 MET B SD 1 ATOM 3894 C CE . MET C 1 128 ? 4.192 26.238 10.884 1.00 46.28 ? 128 MET B CE 1 ATOM 3895 N N . VAL C 1 129 ? 5.191 28.095 15.365 1.00 44.68 ? 129 VAL B N 1 ATOM 3896 C CA . VAL C 1 129 ? 4.478 27.376 16.462 1.00 45.43 ? 129 VAL B CA 1 ATOM 3897 C C . VAL C 1 129 ? 2.954 27.432 16.490 1.00 45.93 ? 129 VAL B C 1 ATOM 3898 O O . VAL C 1 129 ? 2.345 28.491 16.666 1.00 45.70 ? 129 VAL B O 1 ATOM 3899 C CB . VAL C 1 129 ? 5.016 27.701 17.910 1.00 45.44 ? 129 VAL B CB 1 ATOM 3900 C CG1 . VAL C 1 129 ? 6.113 26.713 18.329 1.00 45.44 ? 129 VAL B CG1 1 ATOM 3901 C CG2 . VAL C 1 129 ? 5.476 29.156 18.046 1.00 45.26 ? 129 VAL B CG2 1 ATOM 3902 N N . HIS C 1 130 ? 2.357 26.258 16.337 1.00 46.91 ? 130 HIS B N 1 ATOM 3903 C CA . HIS C 1 130 ? 0.916 26.097 16.415 1.00 48.09 ? 130 HIS B CA 1 ATOM 3904 C C . HIS C 1 130 ? 0.451 26.314 17.858 1.00 48.71 ? 130 HIS B C 1 ATOM 3905 O O . HIS C 1 130 ? 1.254 26.502 18.761 1.00 48.65 ? 130 HIS B O 1 ATOM 3906 C CB . HIS C 1 130 ? 0.503 24.705 15.888 1.00 48.22 ? 130 HIS B CB 1 ATOM 3907 C CG . HIS C 1 130 ? 0.557 24.560 14.385 1.00 48.69 ? 130 HIS B CG 1 ATOM 3908 N ND1 . HIS C 1 130 ? -0.537 24.174 13.632 1.00 48.36 ? 130 HIS B ND1 1 ATOM 3909 C CD2 . HIS C 1 130 ? 1.575 24.723 13.501 1.00 48.54 ? 130 HIS B CD2 1 ATOM 3910 C CE1 . HIS C 1 130 ? -0.197 24.114 12.356 1.00 48.48 ? 130 HIS B CE1 1 ATOM 3911 N NE2 . HIS C 1 130 ? 1.079 24.445 12.249 1.00 48.38 ? 130 HIS B NE2 1 ATOM 3912 N N . ASP C 1 131 ? -0.852 26.307 18.066 1.00 49.95 ? 131 ASP B N 1 ATOM 3913 C CA . ASP C 1 131 ? -1.400 26.479 19.391 1.00 51.33 ? 131 ASP B CA 1 ATOM 3914 C C . ASP C 1 131 ? -1.711 25.123 20.024 1.00 52.46 ? 131 ASP B C 1 ATOM 3915 O O . ASP C 1 131 ? -1.246 24.086 19.556 1.00 52.39 ? 131 ASP B O 1 ATOM 3916 C CB . ASP C 1 131 ? -2.672 27.319 19.304 1.00 51.30 ? 131 ASP B CB 1 ATOM 3917 C CG . ASP C 1 131 ? -3.071 27.912 20.636 1.00 51.15 ? 131 ASP B CG 1 ATOM 3918 O OD1 . ASP C 1 131 ? -2.303 28.754 21.153 1.00 50.88 ? 131 ASP B OD1 1 ATOM 3919 O OD2 . ASP C 1 131 ? -4.152 27.538 21.153 1.00 50.31 ? 131 ASP B OD2 1 ATOM 3920 N N . CYS C 1 132 ? -2.480 25.162 21.110 1.00 54.35 ? 132 CYS B N 1 ATOM 3921 C CA . CYS C 1 132 ? -3.047 23.987 21.762 1.00 55.79 ? 132 CYS B CA 1 ATOM 3922 C C . CYS C 1 132 ? -4.567 23.899 21.429 1.00 56.57 ? 132 CYS B C 1 ATOM 3923 O O . CYS C 1 132 ? -5.022 23.325 20.406 1.00 57.19 ? 132 CYS B O 1 ATOM 3924 C CB . CYS C 1 132 ? -2.853 24.120 23.267 1.00 55.51 ? 132 CYS B CB 1 ATOM 3925 S SG . CYS C 1 132 ? -1.140 24.487 23.941 1.00 58.09 ? 132 CYS B SG 1 ATOM 3926 N N . LEU D 2 1 ? 43.676 56.621 27.786 1.00 33.65 ? 1 LEU V N 1 ATOM 3927 C CA . LEU D 2 1 ? 43.426 55.562 26.759 1.00 33.64 ? 1 LEU V CA 1 ATOM 3928 C C . LEU D 2 1 ? 41.938 55.281 26.655 1.00 33.11 ? 1 LEU V C 1 ATOM 3929 O O . LEU D 2 1 ? 41.224 55.306 27.652 1.00 32.97 ? 1 LEU V O 1 ATOM 3930 C CB . LEU D 2 1 ? 44.154 54.262 27.156 1.00 34.12 ? 1 LEU V CB 1 ATOM 3931 C CG . LEU D 2 1 ? 44.734 53.188 26.202 1.00 34.25 ? 1 LEU V CG 1 ATOM 3932 C CD1 . LEU D 2 1 ? 44.376 51.798 26.737 1.00 33.97 ? 1 LEU V CD1 1 ATOM 3933 C CD2 . LEU D 2 1 ? 44.315 53.314 24.730 1.00 34.52 ? 1 LEU V CD2 1 ATOM 3934 N N . GLN D 2 2 ? 41.464 54.991 25.459 1.00 32.72 ? 2 GLN V N 1 ATOM 3935 C CA . GLN D 2 2 ? 40.057 54.705 25.326 1.00 33.04 ? 2 GLN V CA 1 ATOM 3936 C C . GLN D 2 2 ? 39.787 53.260 24.966 1.00 33.31 ? 2 GLN V C 1 ATOM 3937 O O . GLN D 2 2 ? 40.175 52.805 23.901 1.00 33.60 ? 2 GLN V O 1 ATOM 3938 C CB . GLN D 2 2 ? 39.423 55.640 24.319 1.00 32.84 ? 2 GLN V CB 1 ATOM 3939 C CG . GLN D 2 2 ? 39.586 57.077 24.697 1.00 33.52 ? 2 GLN V CG 1 ATOM 3940 C CD . GLN D 2 2 ? 38.341 57.877 24.435 1.00 34.24 ? 2 GLN V CD 1 ATOM 3941 O OE1 . GLN D 2 2 ? 37.910 58.022 23.291 1.00 34.98 ? 2 GLN V OE1 1 ATOM 3942 N NE2 . GLN D 2 2 ? 37.750 58.411 25.498 1.00 33.90 ? 2 GLN V NE2 1 ATOM 3943 N N . CYS D 2 3 ? 39.139 52.539 25.874 1.00 33.54 ? 3 CYS V N 1 ATOM 3944 C CA . CYS D 2 3 ? 38.719 51.175 25.621 1.00 34.11 ? 3 CYS V CA 1 ATOM 3945 C C . CYS D 2 3 ? 37.233 51.147 25.415 1.00 34.50 ? 3 CYS V C 1 ATOM 3946 O O . CYS D 2 3 ? 36.549 52.122 25.692 1.00 34.89 ? 3 CYS V O 1 ATOM 3947 C CB . CYS D 2 3 ? 39.083 50.259 26.778 1.00 33.69 ? 3 CYS V CB 1 ATOM 3948 S SG . CYS D 2 3 ? 40.828 49.718 26.811 1.00 35.64 ? 3 CYS V SG 1 ATOM 3949 N N . MET D 2 4 ? 36.723 50.028 24.932 1.00 34.98 ? 4 MET V N 1 ATOM 3950 C CA . MET D 2 4 ? 35.317 49.954 24.647 1.00 35.80 ? 4 MET V CA 1 ATOM 3951 C C . MET D 2 4 ? 34.693 49.140 25.718 1.00 35.92 ? 4 MET V C 1 ATOM 3952 O O . MET D 2 4 ? 34.614 47.944 25.583 1.00 37.00 ? 4 MET V O 1 ATOM 3953 C CB . MET D 2 4 ? 35.081 49.248 23.315 1.00 36.15 ? 4 MET V CB 1 ATOM 3954 C CG . MET D 2 4 ? 35.214 50.119 22.113 1.00 37.06 ? 4 MET V CG 1 ATOM 3955 S SD . MET D 2 4 ? 33.646 50.904 21.899 1.00 41.28 ? 4 MET V SD 1 ATOM 3956 C CE . MET D 2 4 ? 34.050 51.994 20.536 1.00 41.24 ? 4 MET V CE 1 ATOM 3957 N N . GLN D 2 5 ? 34.248 49.737 26.801 1.00 35.86 ? 5 GLN V N 1 ATOM 3958 C CA . GLN D 2 5 ? 33.602 48.890 27.787 1.00 35.87 ? 5 GLN V CA 1 ATOM 3959 C C . GLN D 2 5 ? 32.213 48.510 27.325 1.00 36.09 ? 5 GLN V C 1 ATOM 3960 O O . GLN D 2 5 ? 31.458 49.339 26.842 1.00 35.83 ? 5 GLN V O 1 ATOM 3961 C CB . GLN D 2 5 ? 33.567 49.511 29.189 1.00 35.68 ? 5 GLN V CB 1 ATOM 3962 C CG . GLN D 2 5 ? 32.836 48.647 30.207 1.00 34.63 ? 5 GLN V CG 1 ATOM 3963 C CD . GLN D 2 5 ? 31.363 48.941 30.232 1.00 33.97 ? 5 GLN V CD 1 ATOM 3964 O OE1 . GLN D 2 5 ? 30.970 50.091 30.176 1.00 36.45 ? 5 GLN V OE1 1 ATOM 3965 N NE2 . GLN D 2 5 ? 30.542 47.916 30.337 1.00 33.68 ? 5 GLN V NE2 1 ATOM 3966 N N . CYS D 2 6 ? 31.918 47.226 27.446 1.00 36.91 ? 6 CYS V N 1 ATOM 3967 C CA . CYS D 2 6 ? 30.553 46.721 27.409 1.00 38.08 ? 6 CYS V CA 1 ATOM 3968 C C . CYS D 2 6 ? 30.551 45.340 28.071 1.00 37.73 ? 6 CYS V C 1 ATOM 3969 O O . CYS D 2 6 ? 31.456 44.542 27.849 1.00 37.09 ? 6 CYS V O 1 ATOM 3970 C CB . CYS D 2 6 ? 29.949 46.739 25.990 1.00 37.98 ? 6 CYS V CB 1 ATOM 3971 S SG . CYS D 2 6 ? 30.818 45.754 24.670 1.00 42.94 ? 6 CYS V SG 1 ATOM 3972 N N . GLU D 2 7 ? 29.581 45.127 28.960 1.00 38.10 ? 7 GLU V N 1 ATOM 3973 C CA . GLU D 2 7 ? 29.301 43.824 29.530 1.00 38.80 ? 7 GLU V CA 1 ATOM 3974 C C . GLU D 2 7 ? 28.553 43.060 28.439 1.00 39.14 ? 7 GLU V C 1 ATOM 3975 O O . GLU D 2 7 ? 28.403 43.583 27.330 1.00 39.84 ? 7 GLU V O 1 ATOM 3976 C CB . GLU D 2 7 ? 28.439 43.974 30.776 1.00 38.89 ? 7 GLU V CB 1 ATOM 3977 C CG . GLU D 2 7 ? 28.556 42.847 31.770 1.00 40.70 ? 7 GLU V CG 1 ATOM 3978 C CD . GLU D 2 7 ? 29.990 42.629 32.208 1.00 43.52 ? 7 GLU V CD 1 ATOM 3979 O OE1 . GLU D 2 7 ? 30.691 43.624 32.508 1.00 44.92 ? 7 GLU V OE1 1 ATOM 3980 O OE2 . GLU D 2 7 ? 30.424 41.462 32.246 1.00 45.20 ? 7 GLU V OE2 1 ATOM 3981 N N . SER D 2 8 ? 28.088 41.842 28.713 1.00 38.78 ? 8 SER V N 1 ATOM 3982 C CA . SER D 2 8 ? 27.425 41.081 27.678 1.00 38.30 ? 8 SER V CA 1 ATOM 3983 C C . SER D 2 8 ? 26.025 41.587 27.440 1.00 38.31 ? 8 SER V C 1 ATOM 3984 O O . SER D 2 8 ? 25.349 42.060 28.353 1.00 37.83 ? 8 SER V O 1 ATOM 3985 C CB . SER D 2 8 ? 27.371 39.615 28.031 1.00 38.52 ? 8 SER V CB 1 ATOM 3986 O OG . SER D 2 8 ? 26.426 38.954 27.210 1.00 39.20 ? 8 SER V OG 1 ATOM 3987 N N . ASN D 2 9 ? 25.600 41.433 26.192 1.00 38.82 ? 9 ASN V N 1 ATOM 3988 C CA . ASN D 2 9 ? 24.319 41.947 25.676 1.00 39.53 ? 9 ASN V CA 1 ATOM 3989 C C . ASN D 2 9 ? 23.785 43.239 26.343 1.00 38.93 ? 9 ASN V C 1 ATOM 3990 O O . ASN D 2 9 ? 22.579 43.457 26.507 1.00 38.81 ? 9 ASN V O 1 ATOM 3991 C CB . ASN D 2 9 ? 23.261 40.826 25.463 1.00 40.13 ? 9 ASN V CB 1 ATOM 3992 C CG . ASN D 2 9 ? 22.562 40.395 26.757 1.00 42.36 ? 9 ASN V CG 1 ATOM 3993 O OD1 . ASN D 2 9 ? 23.192 39.854 27.692 1.00 44.52 ? 9 ASN V OD1 1 ATOM 3994 N ND2 . ASN D 2 9 ? 21.234 40.604 26.799 1.00 42.50 ? 9 ASN V ND2 1 ATOM 3995 N N . GLN D 2 10 ? 24.742 44.077 26.725 1.00 38.37 ? 10 GLN V N 1 ATOM 3996 C CA . GLN D 2 10 ? 24.555 45.512 26.834 1.00 37.67 ? 10 GLN V CA 1 ATOM 3997 C C . GLN D 2 10 ? 25.563 46.071 25.851 1.00 37.05 ? 10 GLN V C 1 ATOM 3998 O O . GLN D 2 10 ? 26.712 45.639 25.833 1.00 37.40 ? 10 GLN V O 1 ATOM 3999 C CB . GLN D 2 10 ? 24.791 46.030 28.273 1.00 37.84 ? 10 GLN V CB 1 ATOM 4000 C CG . GLN D 2 10 ? 26.075 45.612 28.940 1.00 37.91 ? 10 GLN V CG 1 ATOM 4001 C CD . GLN D 2 10 ? 26.755 46.740 29.684 1.00 40.82 ? 10 GLN V CD 1 ATOM 4002 O OE1 . GLN D 2 10 ? 27.415 46.503 30.694 1.00 41.86 ? 10 GLN V OE1 1 ATOM 4003 N NE2 . GLN D 2 10 ? 26.629 47.983 29.177 1.00 43.41 ? 10 GLN V NE2 1 ATOM 4004 N N . SER D 2 11 ? 25.144 46.995 25.003 1.00 36.16 ? 11 SER V N 1 ATOM 4005 C CA . SER D 2 11 ? 26.027 47.501 23.940 1.00 35.40 ? 11 SER V CA 1 ATOM 4006 C C . SER D 2 11 ? 27.288 48.167 24.452 1.00 34.25 ? 11 SER V C 1 ATOM 4007 O O . SER D 2 11 ? 27.303 48.702 25.537 1.00 34.87 ? 11 SER V O 1 ATOM 4008 C CB . SER D 2 11 ? 25.286 48.552 23.148 1.00 35.84 ? 11 SER V CB 1 ATOM 4009 O OG . SER D 2 11 ? 25.028 49.633 24.018 1.00 36.86 ? 11 SER V OG 1 ATOM 4010 N N . CYS D 2 12 ? 28.330 48.177 23.644 1.00 32.87 ? 12 CYS V N 1 ATOM 4011 C CA . CYS D 2 12 ? 29.555 48.851 24.002 1.00 32.31 ? 12 CYS V CA 1 ATOM 4012 C C . CYS D 2 12 ? 29.420 50.329 24.188 1.00 30.90 ? 12 CYS V C 1 ATOM 4013 O O . CYS D 2 12 ? 28.504 50.941 23.674 1.00 30.81 ? 12 CYS V O 1 ATOM 4014 C CB . CYS D 2 12 ? 30.616 48.614 22.964 1.00 32.31 ? 12 CYS V CB 1 ATOM 4015 S SG . CYS D 2 12 ? 31.399 46.977 22.990 1.00 38.68 ? 12 CYS V SG 1 ATOM 4016 N N . LEU D 2 13 ? 30.362 50.878 24.945 1.00 29.80 ? 13 LEU V N 1 ATOM 4017 C CA . LEU D 2 13 ? 30.488 52.295 25.224 1.00 28.51 ? 13 LEU V CA 1 ATOM 4018 C C . LEU D 2 13 ? 31.958 52.568 25.226 1.00 28.03 ? 13 LEU V C 1 ATOM 4019 O O . LEU D 2 13 ? 32.741 51.659 25.484 1.00 28.08 ? 13 LEU V O 1 ATOM 4020 C CB . LEU D 2 13 ? 29.946 52.596 26.608 1.00 28.21 ? 13 LEU V CB 1 ATOM 4021 C CG . LEU D 2 13 ? 28.615 53.331 26.761 1.00 27.93 ? 13 LEU V CG 1 ATOM 4022 C CD1 . LEU D 2 13 ? 27.491 52.777 25.903 1.00 28.63 ? 13 LEU V CD1 1 ATOM 4023 C CD2 . LEU D 2 13 ? 28.206 53.319 28.206 1.00 27.65 ? 13 LEU V CD2 1 ATOM 4024 N N . VAL D 2 14 ? 32.344 53.805 24.938 1.00 27.55 ? 14 VAL V N 1 ATOM 4025 C CA . VAL D 2 14 ? 33.746 54.187 24.980 1.00 27.47 ? 14 VAL V CA 1 ATOM 4026 C C . VAL D 2 14 ? 34.010 54.607 26.394 1.00 28.03 ? 14 VAL V C 1 ATOM 4027 O O . VAL D 2 14 ? 33.231 55.335 26.965 1.00 28.23 ? 14 VAL V O 1 ATOM 4028 C CB . VAL D 2 14 ? 34.055 55.345 24.040 1.00 27.12 ? 14 VAL V CB 1 ATOM 4029 C CG1 . VAL D 2 14 ? 35.538 55.551 23.916 1.00 26.50 ? 14 VAL V CG1 1 ATOM 4030 C CG2 . VAL D 2 14 ? 33.503 55.058 22.685 1.00 27.43 ? 14 VAL V CG2 1 ATOM 4031 N N . GLU D 2 15 ? 35.096 54.130 26.969 1.00 28.80 ? 15 GLU V N 1 ATOM 4032 C CA . GLU D 2 15 ? 35.396 54.382 28.354 1.00 30.23 ? 15 GLU V CA 1 ATOM 4033 C C . GLU D 2 15 ? 36.816 54.907 28.374 1.00 30.54 ? 15 GLU V C 1 ATOM 4034 O O . GLU D 2 15 ? 37.687 54.321 27.745 1.00 30.97 ? 15 GLU V O 1 ATOM 4035 C CB . GLU D 2 15 ? 35.253 53.063 29.138 1.00 30.91 ? 15 GLU V CB 1 ATOM 4036 C CG . GLU D 2 15 ? 36.111 52.877 30.427 1.00 34.68 ? 15 GLU V CG 1 ATOM 4037 C CD . GLU D 2 15 ? 36.130 51.411 30.957 1.00 40.18 ? 15 GLU V CD 1 ATOM 4038 O OE1 . GLU D 2 15 ? 36.546 50.491 30.204 1.00 42.29 ? 15 GLU V OE1 1 ATOM 4039 O OE2 . GLU D 2 15 ? 35.758 51.172 32.139 1.00 42.36 ? 15 GLU V OE2 1 ATOM 4040 N N . GLU D 2 16 ? 37.053 56.026 29.056 1.00 31.06 ? 16 GLU V N 1 ATOM 4041 C CA . GLU D 2 16 ? 38.422 56.499 29.284 1.00 31.31 ? 16 GLU V CA 1 ATOM 4042 C C . GLU D 2 16 ? 39.022 55.650 30.395 1.00 31.43 ? 16 GLU V C 1 ATOM 4043 O O . GLU D 2 16 ? 38.331 55.274 31.338 1.00 31.59 ? 16 GLU V O 1 ATOM 4044 C CB . GLU D 2 16 ? 38.427 57.972 29.684 1.00 31.31 ? 16 GLU V CB 1 ATOM 4045 C CG . GLU D 2 16 ? 39.353 58.867 28.850 1.00 32.20 ? 16 GLU V CG 1 ATOM 4046 C CD . GLU D 2 16 ? 40.823 58.811 29.267 1.00 34.07 ? 16 GLU V CD 1 ATOM 4047 O OE1 . GLU D 2 16 ? 41.560 59.796 28.990 1.00 34.13 ? 16 GLU V OE1 1 ATOM 4048 O OE2 . GLU D 2 16 ? 41.246 57.791 29.866 1.00 35.41 ? 16 GLU V OE2 1 ATOM 4049 N N . CYS D 2 17 ? 40.297 55.320 30.287 1.00 31.66 ? 17 CYS V N 1 ATOM 4050 C CA . CYS D 2 17 ? 40.885 54.473 31.298 1.00 32.12 ? 17 CYS V CA 1 ATOM 4051 C C . CYS D 2 17 ? 41.684 55.255 32.310 1.00 32.23 ? 17 CYS V C 1 ATOM 4052 O O . CYS D 2 17 ? 42.482 56.125 31.958 1.00 32.12 ? 17 CYS V O 1 ATOM 4053 C CB . CYS D 2 17 ? 41.778 53.400 30.684 1.00 32.28 ? 17 CYS V CB 1 ATOM 4054 S SG . CYS D 2 17 ? 41.093 52.405 29.347 1.00 33.49 ? 17 CYS V SG 1 ATOM 4055 N N . ALA D 2 18 ? 41.472 54.902 33.571 1.00 32.62 ? 18 ALA V N 1 ATOM 4056 C CA . ALA D 2 18 ? 42.270 55.386 34.685 1.00 33.48 ? 18 ALA V CA 1 ATOM 4057 C C . ALA D 2 18 ? 43.780 55.295 34.451 1.00 33.97 ? 18 ALA V C 1 ATOM 4058 O O . ALA D 2 18 ? 44.260 54.347 33.854 1.00 33.82 ? 18 ALA V O 1 ATOM 4059 C CB . ALA D 2 18 ? 41.909 54.596 35.930 1.00 33.52 ? 18 ALA V CB 1 ATOM 4060 N N . LEU D 2 19 ? 44.528 56.276 34.949 1.00 34.90 ? 19 LEU V N 1 ATOM 4061 C CA . LEU D 2 19 ? 45.976 56.132 35.066 1.00 35.72 ? 19 LEU V CA 1 ATOM 4062 C C . LEU D 2 19 ? 46.247 54.801 35.777 1.00 36.08 ? 19 LEU V C 1 ATOM 4063 O O . LEU D 2 19 ? 45.542 54.449 36.726 1.00 36.34 ? 19 LEU V O 1 ATOM 4064 C CB . LEU D 2 19 ? 46.579 57.319 35.841 1.00 35.84 ? 19 LEU V CB 1 ATOM 4065 C CG . LEU D 2 19 ? 46.686 57.336 37.380 1.00 36.42 ? 19 LEU V CG 1 ATOM 4066 C CD1 . LEU D 2 19 ? 48.099 56.953 37.879 1.00 36.48 ? 19 LEU V CD1 1 ATOM 4067 C CD2 . LEU D 2 19 ? 46.301 58.708 37.926 1.00 36.96 ? 19 LEU V CD2 1 ATOM 4068 N N . GLY D 2 20 ? 47.240 54.050 35.310 1.00 36.39 ? 20 GLY V N 1 ATOM 4069 C CA . GLY D 2 20 ? 47.552 52.753 35.921 1.00 36.91 ? 20 GLY V CA 1 ATOM 4070 C C . GLY D 2 20 ? 47.025 51.596 35.086 1.00 37.11 ? 20 GLY V C 1 ATOM 4071 O O . GLY D 2 20 ? 47.798 50.712 34.672 1.00 37.42 ? 20 GLY V O 1 ATOM 4072 N N . GLN D 2 21 ? 45.711 51.583 34.844 1.00 36.76 ? 21 GLN V N 1 ATOM 4073 C CA . GLN D 2 21 ? 45.183 50.816 33.707 1.00 36.36 ? 21 GLN V CA 1 ATOM 4074 C C . GLN D 2 21 ? 45.755 51.412 32.411 1.00 35.83 ? 21 GLN V C 1 ATOM 4075 O O . GLN D 2 21 ? 46.215 52.561 32.394 1.00 35.97 ? 21 GLN V O 1 ATOM 4076 C CB . GLN D 2 21 ? 43.652 50.818 33.676 1.00 36.30 ? 21 GLN V CB 1 ATOM 4077 C CG . GLN D 2 21 ? 43.023 49.572 34.259 1.00 36.23 ? 21 GLN V CG 1 ATOM 4078 C CD . GLN D 2 21 ? 41.635 49.804 34.833 1.00 37.24 ? 21 GLN V CD 1 ATOM 4079 O OE1 . GLN D 2 21 ? 41.218 50.946 35.054 1.00 38.27 ? 21 GLN V OE1 1 ATOM 4080 N NE2 . GLN D 2 21 ? 40.914 48.715 35.095 1.00 37.24 ? 21 GLN V NE2 1 ATOM 4081 N N . ASP D 2 22 ? 45.768 50.618 31.348 1.00 35.12 ? 22 ASP V N 1 ATOM 4082 C CA . ASP D 2 22 ? 46.212 51.083 30.038 1.00 34.60 ? 22 ASP V CA 1 ATOM 4083 C C . ASP D 2 22 ? 46.460 49.917 29.084 1.00 33.77 ? 22 ASP V C 1 ATOM 4084 O O . ASP D 2 22 ? 47.398 49.933 28.280 1.00 34.03 ? 22 ASP V O 1 ATOM 4085 C CB . ASP D 2 22 ? 47.429 52.044 30.118 1.00 34.98 ? 22 ASP V CB 1 ATOM 4086 C CG . ASP D 2 22 ? 48.658 51.411 30.777 1.00 35.96 ? 22 ASP V CG 1 ATOM 4087 O OD1 . ASP D 2 22 ? 49.765 52.005 30.648 1.00 37.13 ? 22 ASP V OD1 1 ATOM 4088 O OD2 . ASP D 2 22 ? 48.518 50.337 31.416 1.00 35.33 ? 22 ASP V OD2 1 ATOM 4089 N N . LEU D 2 23 ? 45.621 48.900 29.190 1.00 32.36 ? 23 LEU V N 1 ATOM 4090 C CA . LEU D 2 23 ? 45.463 47.981 28.091 1.00 31.39 ? 23 LEU V CA 1 ATOM 4091 C C . LEU D 2 23 ? 43.987 47.919 27.778 1.00 30.60 ? 23 LEU V C 1 ATOM 4092 O O . LEU D 2 23 ? 43.170 48.334 28.595 1.00 30.78 ? 23 LEU V O 1 ATOM 4093 C CB . LEU D 2 23 ? 46.003 46.607 28.449 1.00 31.43 ? 23 LEU V CB 1 ATOM 4094 C CG . LEU D 2 23 ? 47.518 46.427 28.541 1.00 32.06 ? 23 LEU V CG 1 ATOM 4095 C CD1 . LEU D 2 23 ? 47.826 44.944 28.712 1.00 31.10 ? 23 LEU V CD1 1 ATOM 4096 C CD2 . LEU D 2 23 ? 48.274 47.016 27.328 1.00 31.84 ? 23 LEU V CD2 1 ATOM 4097 N N . CYS D 2 24 ? 43.636 47.435 26.598 1.00 29.45 ? 24 CYS V N 1 ATOM 4098 C CA . CYS D 2 24 ? 42.244 47.195 26.294 1.00 28.93 ? 24 CYS V CA 1 ATOM 4099 C C . CYS D 2 24 ? 41.960 45.726 26.435 1.00 28.35 ? 24 CYS V C 1 ATOM 4100 O O . CYS D 2 24 ? 42.826 44.914 26.183 1.00 28.99 ? 24 CYS V O 1 ATOM 4101 C CB . CYS D 2 24 ? 41.936 47.668 24.892 1.00 29.17 ? 24 CYS V CB 1 ATOM 4102 S SG . CYS D 2 24 ? 41.467 49.367 24.875 1.00 30.86 ? 24 CYS V SG 1 ATOM 4103 N N . ARG D 2 25 ? 40.759 45.350 26.830 1.00 27.43 ? 25 ARG V N 1 ATOM 4104 C CA . ARG D 2 25 ? 40.507 43.931 27.046 1.00 26.73 ? 25 ARG V CA 1 ATOM 4105 C C . ARG D 2 25 ? 39.275 43.413 26.289 1.00 27.22 ? 25 ARG V C 1 ATOM 4106 O O . ARG D 2 25 ? 38.234 44.077 26.226 1.00 27.23 ? 25 ARG V O 1 ATOM 4107 C CB . ARG D 2 25 ? 40.424 43.641 28.561 1.00 26.31 ? 25 ARG V CB 1 ATOM 4108 C CG . ARG D 2 25 ? 39.598 42.434 28.961 1.00 23.53 ? 25 ARG V CG 1 ATOM 4109 C CD . ARG D 2 25 ? 39.357 42.358 30.450 1.00 19.21 ? 25 ARG V CD 1 ATOM 4110 N NE . ARG D 2 25 ? 38.140 43.014 30.969 1.00 15.57 ? 25 ARG V NE 1 ATOM 4111 C CZ . ARG D 2 25 ? 36.877 42.625 30.763 1.00 14.12 ? 25 ARG V CZ 1 ATOM 4112 N NH1 . ARG D 2 25 ? 36.572 41.608 29.977 1.00 15.57 ? 25 ARG V NH1 1 ATOM 4113 N NH2 . ARG D 2 25 ? 35.887 43.277 31.325 1.00 13.25 ? 25 ARG V NH2 1 ATOM 4114 N N . THR D 2 26 ? 39.407 42.226 25.709 1.00 27.32 ? 26 THR V N 1 ATOM 4115 C CA . THR D 2 26 ? 38.250 41.479 25.260 1.00 27.64 ? 26 THR V CA 1 ATOM 4116 C C . THR D 2 26 ? 38.317 40.149 25.958 1.00 27.52 ? 26 THR V C 1 ATOM 4117 O O . THR D 2 26 ? 39.317 39.450 25.836 1.00 27.47 ? 26 THR V O 1 ATOM 4118 C CB . THR D 2 26 ? 38.312 41.217 23.761 1.00 27.94 ? 26 THR V CB 1 ATOM 4119 O OG1 . THR D 2 26 ? 38.866 42.362 23.093 1.00 29.76 ? 26 THR V OG1 1 ATOM 4120 C CG2 . THR D 2 26 ? 36.934 40.911 23.209 1.00 27.40 ? 26 THR V CG2 1 ATOM 4121 N N . THR D 2 27 ? 37.277 39.812 26.709 1.00 27.49 ? 27 THR V N 1 ATOM 4122 C CA . THR D 2 27 ? 37.166 38.495 27.302 1.00 27.77 ? 27 THR V CA 1 ATOM 4123 C C . THR D 2 27 ? 35.950 37.806 26.720 1.00 28.53 ? 27 THR V C 1 ATOM 4124 O O . THR D 2 27 ? 34.818 38.249 26.918 1.00 28.71 ? 27 THR V O 1 ATOM 4125 C CB . THR D 2 27 ? 36.985 38.588 28.799 1.00 27.56 ? 27 THR V CB 1 ATOM 4126 O OG1 . THR D 2 27 ? 38.171 39.114 29.374 1.00 28.74 ? 27 THR V OG1 1 ATOM 4127 C CG2 . THR D 2 27 ? 36.768 37.249 29.390 1.00 27.33 ? 27 THR V CG2 1 ATOM 4128 N N . VAL D 2 28 ? 36.184 36.714 26.000 1.00 29.34 ? 28 VAL V N 1 ATOM 4129 C CA . VAL D 2 28 ? 35.099 35.908 25.446 1.00 29.52 ? 28 VAL V CA 1 ATOM 4130 C C . VAL D 2 28 ? 35.118 34.462 25.979 1.00 30.12 ? 28 VAL V C 1 ATOM 4131 O O . VAL D 2 28 ? 36.175 33.835 26.091 1.00 30.06 ? 28 VAL V O 1 ATOM 4132 C CB . VAL D 2 28 ? 35.157 35.932 23.914 1.00 29.29 ? 28 VAL V CB 1 ATOM 4133 C CG1 . VAL D 2 28 ? 36.563 35.632 23.433 1.00 28.38 ? 28 VAL V CG1 1 ATOM 4134 C CG2 . VAL D 2 28 ? 34.124 34.976 23.309 1.00 29.41 ? 28 VAL V CG2 1 ATOM 4135 N N . LEU D 2 29 ? 33.946 33.947 26.319 1.00 30.71 ? 29 LEU V N 1 ATOM 4136 C CA . LEU D 2 29 ? 33.813 32.545 26.644 1.00 31.59 ? 29 LEU V CA 1 ATOM 4137 C C . LEU D 2 29 ? 32.673 31.901 25.841 1.00 32.48 ? 29 LEU V C 1 ATOM 4138 O O . LEU D 2 29 ? 31.581 32.456 25.755 1.00 32.16 ? 29 LEU V O 1 ATOM 4139 C CB . LEU D 2 29 ? 33.626 32.378 28.143 1.00 31.37 ? 29 LEU V CB 1 ATOM 4140 C CG . LEU D 2 29 ? 32.356 31.658 28.612 1.00 32.33 ? 29 LEU V CG 1 ATOM 4141 C CD1 . LEU D 2 29 ? 32.626 30.623 29.708 1.00 33.24 ? 29 LEU V CD1 1 ATOM 4142 C CD2 . LEU D 2 29 ? 31.282 32.664 29.059 1.00 32.91 ? 29 LEU V CD2 1 ATOM 4143 N N . ARG D 2 30 ? 32.956 30.725 25.266 1.00 34.17 ? 30 ARG V N 1 ATOM 4144 C CA . ARG D 2 30 ? 32.036 29.952 24.393 1.00 35.33 ? 30 ARG V CA 1 ATOM 4145 C C . ARG D 2 30 ? 31.676 28.551 24.925 1.00 36.35 ? 30 ARG V C 1 ATOM 4146 O O . ARG D 2 30 ? 32.476 27.890 25.587 1.00 36.43 ? 30 ARG V O 1 ATOM 4147 C CB . ARG D 2 30 ? 32.659 29.750 23.015 1.00 34.89 ? 30 ARG V CB 1 ATOM 4148 C CG . ARG D 2 30 ? 32.914 30.991 22.266 1.00 35.73 ? 30 ARG V CG 1 ATOM 4149 C CD . ARG D 2 30 ? 33.926 30.739 21.203 1.00 37.80 ? 30 ARG V CD 1 ATOM 4150 N NE . ARG D 2 30 ? 33.886 31.779 20.178 1.00 40.40 ? 30 ARG V NE 1 ATOM 4151 C CZ . ARG D 2 30 ? 34.661 32.865 20.161 1.00 42.22 ? 30 ARG V CZ 1 ATOM 4152 N NH1 . ARG D 2 30 ? 35.564 33.095 21.112 1.00 42.85 ? 30 ARG V NH1 1 ATOM 4153 N NH2 . ARG D 2 30 ? 34.535 33.731 19.170 1.00 44.05 ? 30 ARG V NH2 1 ATOM 4154 N N . GLU D 2 31 ? 30.480 28.086 24.583 1.00 37.68 ? 31 GLU V N 1 ATOM 4155 C CA . GLU D 2 31 ? 30.080 26.713 24.856 1.00 38.65 ? 31 GLU V CA 1 ATOM 4156 C C . GLU D 2 31 ? 29.789 25.993 23.545 1.00 38.85 ? 31 GLU V C 1 ATOM 4157 O O . GLU D 2 31 ? 29.879 26.583 22.479 1.00 38.89 ? 31 GLU V O 1 ATOM 4158 C CB . GLU D 2 31 ? 28.852 26.712 25.747 1.00 39.08 ? 31 GLU V CB 1 ATOM 4159 C CG . GLU D 2 31 ? 29.101 27.312 27.119 1.00 40.84 ? 31 GLU V CG 1 ATOM 4160 C CD . GLU D 2 31 ? 28.015 28.307 27.516 1.00 44.36 ? 31 GLU V CD 1 ATOM 4161 O OE1 . GLU D 2 31 ? 27.125 27.951 28.334 1.00 46.09 ? 31 GLU V OE1 1 ATOM 4162 O OE2 . GLU D 2 31 ? 28.040 29.446 26.992 1.00 45.50 ? 31 GLU V OE2 1 ATOM 4163 N N . TRP D 2 32 ? 29.465 24.713 23.625 1.00 39.37 ? 32 TRP V N 1 ATOM 4164 C CA . TRP D 2 32 ? 29.145 23.933 22.449 1.00 40.11 ? 32 TRP V CA 1 ATOM 4165 C C . TRP D 2 32 ? 28.426 22.676 22.863 1.00 39.97 ? 32 TRP V C 1 ATOM 4166 O O . TRP D 2 32 ? 28.769 22.082 23.867 1.00 39.87 ? 32 TRP V O 1 ATOM 4167 C CB . TRP D 2 32 ? 30.407 23.554 21.683 1.00 40.32 ? 32 TRP V CB 1 ATOM 4168 C CG . TRP D 2 32 ? 30.187 22.393 20.703 1.00 43.38 ? 32 TRP V CG 1 ATOM 4169 C CD1 . TRP D 2 32 ? 30.244 21.045 20.990 1.00 44.93 ? 32 TRP V CD1 1 ATOM 4170 C CD2 . TRP D 2 32 ? 29.869 22.481 19.296 1.00 44.60 ? 32 TRP V CD2 1 ATOM 4171 N NE1 . TRP D 2 32 ? 29.995 20.305 19.855 1.00 44.29 ? 32 TRP V NE1 1 ATOM 4172 C CE2 . TRP D 2 32 ? 29.768 21.154 18.803 1.00 44.19 ? 32 TRP V CE2 1 ATOM 4173 C CE3 . TRP D 2 32 ? 29.674 23.546 18.408 1.00 45.53 ? 32 TRP V CE3 1 ATOM 4174 C CZ2 . TRP D 2 32 ? 29.477 20.866 17.464 1.00 44.79 ? 32 TRP V CZ2 1 ATOM 4175 C CZ3 . TRP D 2 32 ? 29.383 23.254 17.069 1.00 47.12 ? 32 TRP V CZ3 1 ATOM 4176 C CH2 . TRP D 2 32 ? 29.289 21.919 16.614 1.00 46.26 ? 32 TRP V CH2 1 ATOM 4177 N N . GLN D 2 33 ? 27.441 22.269 22.072 1.00 40.18 ? 33 GLN V N 1 ATOM 4178 C CA . GLN D 2 33 ? 26.798 20.985 22.254 1.00 40.35 ? 33 GLN V CA 1 ATOM 4179 C C . GLN D 2 33 ? 26.057 20.582 20.983 1.00 40.64 ? 33 GLN V C 1 ATOM 4180 O O . GLN D 2 33 ? 24.839 20.699 20.904 1.00 40.76 ? 33 GLN V O 1 ATOM 4181 C CB . GLN D 2 33 ? 25.842 21.049 23.440 1.00 40.27 ? 33 GLN V CB 1 ATOM 4182 C CG . GLN D 2 33 ? 26.444 20.530 24.723 1.00 40.23 ? 33 GLN V CG 1 ATOM 4183 C CD . GLN D 2 33 ? 25.455 20.506 25.878 1.00 40.78 ? 33 GLN V CD 1 ATOM 4184 O OE1 . GLN D 2 33 ? 24.910 21.541 26.275 1.00 41.36 ? 33 GLN V OE1 1 ATOM 4185 N NE2 . GLN D 2 33 ? 25.224 19.319 26.433 1.00 40.06 ? 33 GLN V NE2 1 ATOM 4186 N N . ASP D 2 34 ? 26.794 20.106 19.986 1.00 40.85 ? 34 ASP V N 1 ATOM 4187 C CA . ASP D 2 34 ? 26.210 19.789 18.672 1.00 41.24 ? 34 ASP V CA 1 ATOM 4188 C C . ASP D 2 34 ? 25.551 21.018 18.060 1.00 41.11 ? 34 ASP V C 1 ATOM 4189 O O . ASP D 2 34 ? 24.408 21.305 18.394 1.00 41.10 ? 34 ASP V O 1 ATOM 4190 C CB . ASP D 2 34 ? 25.168 18.648 18.780 1.00 41.48 ? 34 ASP V CB 1 ATOM 4191 C CG . ASP D 2 34 ? 25.777 17.228 18.600 1.00 42.50 ? 34 ASP V CG 1 ATOM 4192 O OD1 . ASP D 2 34 ? 26.699 17.027 17.763 1.00 42.67 ? 34 ASP V OD1 1 ATOM 4193 O OD2 . ASP D 2 34 ? 25.298 16.295 19.295 1.00 43.02 ? 34 ASP V OD2 1 ATOM 4194 N N . ASP D 2 35 ? 26.255 21.731 17.176 1.00 41.36 ? 35 ASP V N 1 ATOM 4195 C CA . ASP D 2 35 ? 25.742 22.983 16.541 1.00 42.00 ? 35 ASP V CA 1 ATOM 4196 C C . ASP D 2 35 ? 25.183 24.018 17.543 1.00 41.92 ? 35 ASP V C 1 ATOM 4197 O O . ASP D 2 35 ? 24.209 24.730 17.255 1.00 41.96 ? 35 ASP V O 1 ATOM 4198 C CB . ASP D 2 35 ? 24.715 22.662 15.404 1.00 42.49 ? 35 ASP V CB 1 ATOM 4199 C CG . ASP D 2 35 ? 23.817 23.882 14.996 1.00 43.05 ? 35 ASP V CG 1 ATOM 4200 O OD1 . ASP D 2 35 ? 24.304 24.855 14.343 1.00 43.77 ? 35 ASP V OD1 1 ATOM 4201 O OD2 . ASP D 2 35 ? 22.604 23.838 15.314 1.00 42.01 ? 35 ASP V OD2 1 ATOM 4202 N N . ARG D 2 36 ? 25.796 24.121 18.723 1.00 41.88 ? 36 ARG V N 1 ATOM 4203 C CA . ARG D 2 36 ? 25.216 24.996 19.745 1.00 41.15 ? 36 ARG V CA 1 ATOM 4204 C C . ARG D 2 36 ? 26.131 26.068 20.335 1.00 41.05 ? 36 ARG V C 1 ATOM 4205 O O . ARG D 2 36 ? 25.934 26.473 21.480 1.00 41.55 ? 36 ARG V O 1 ATOM 4206 C CB . ARG D 2 36 ? 24.507 24.170 20.825 1.00 40.77 ? 36 ARG V CB 1 ATOM 4207 C CG . ARG D 2 36 ? 23.002 24.088 20.603 1.00 39.52 ? 36 ARG V CG 1 ATOM 4208 C CD . ARG D 2 36 ? 22.220 24.755 21.721 1.00 39.17 ? 36 ARG V CD 1 ATOM 4209 N NE . ARG D 2 36 ? 22.334 24.026 22.985 1.00 40.25 ? 36 ARG V NE 1 ATOM 4210 C CZ . ARG D 2 36 ? 22.438 22.701 23.087 1.00 41.43 ? 36 ARG V CZ 1 ATOM 4211 N NH1 . ARG D 2 36 ? 22.410 21.958 21.992 1.00 42.73 ? 36 ARG V NH1 1 ATOM 4212 N NH2 . ARG D 2 36 ? 22.552 22.103 24.273 1.00 40.51 ? 36 ARG V NH2 1 ATOM 4213 N N . GLU D 2 37 ? 27.081 26.577 19.551 1.00 40.52 ? 37 GLU V N 1 ATOM 4214 C CA . GLU D 2 37 ? 27.931 27.639 20.061 1.00 40.38 ? 37 GLU V CA 1 ATOM 4215 C C . GLU D 2 37 ? 27.108 28.786 20.669 1.00 39.64 ? 37 GLU V C 1 ATOM 4216 O O . GLU D 2 37 ? 26.447 29.537 19.968 1.00 39.42 ? 37 GLU V O 1 ATOM 4217 C CB . GLU D 2 37 ? 29.003 28.105 19.049 1.00 40.79 ? 37 GLU V CB 1 ATOM 4218 C CG . GLU D 2 37 ? 28.530 28.981 17.861 1.00 43.67 ? 37 GLU V CG 1 ATOM 4219 C CD . GLU D 2 37 ? 29.661 29.854 17.246 1.00 46.68 ? 37 GLU V CD 1 ATOM 4220 O OE1 . GLU D 2 37 ? 29.953 29.702 16.016 1.00 45.43 ? 37 GLU V OE1 1 ATOM 4221 O OE2 . GLU D 2 37 ? 30.245 30.690 18.003 1.00 47.48 ? 37 GLU V OE2 1 ATOM 4222 N N . LEU D 2 38 ? 27.099 28.827 22.002 1.00 39.19 ? 38 LEU V N 1 ATOM 4223 C CA . LEU D 2 38 ? 26.749 30.012 22.781 1.00 38.33 ? 38 LEU V CA 1 ATOM 4224 C C . LEU D 2 38 ? 28.056 30.745 22.998 1.00 37.75 ? 38 LEU V C 1 ATOM 4225 O O . LEU D 2 38 ? 29.110 30.094 23.146 1.00 37.44 ? 38 LEU V O 1 ATOM 4226 C CB . LEU D 2 38 ? 26.194 29.618 24.142 1.00 38.46 ? 38 LEU V CB 1 ATOM 4227 C CG . LEU D 2 38 ? 25.638 30.725 25.037 1.00 38.40 ? 38 LEU V CG 1 ATOM 4228 C CD1 . LEU D 2 38 ? 24.504 31.461 24.337 1.00 39.30 ? 38 LEU V CD1 1 ATOM 4229 C CD2 . LEU D 2 38 ? 25.136 30.130 26.343 1.00 38.90 ? 38 LEU V CD2 1 ATOM 4230 N N . GLU D 2 39 ? 27.995 32.081 23.015 1.00 36.71 ? 39 GLU V N 1 ATOM 4231 C CA . GLU D 2 39 ? 29.211 32.902 23.065 1.00 35.92 ? 39 GLU V CA 1 ATOM 4232 C C . GLU D 2 39 ? 29.043 34.261 23.760 1.00 34.81 ? 39 GLU V C 1 ATOM 4233 O O . GLU D 2 39 ? 28.355 35.131 23.246 1.00 35.14 ? 39 GLU V O 1 ATOM 4234 C CB . GLU D 2 39 ? 29.757 33.084 21.649 1.00 35.93 ? 39 GLU V CB 1 ATOM 4235 C CG . GLU D 2 39 ? 30.935 34.018 21.537 1.00 38.13 ? 39 GLU V CG 1 ATOM 4236 C CD . GLU D 2 39 ? 31.182 34.430 20.096 1.00 42.31 ? 39 GLU V CD 1 ATOM 4237 O OE1 . GLU D 2 39 ? 30.849 35.597 19.729 1.00 42.35 ? 39 GLU V OE1 1 ATOM 4238 O OE2 . GLU D 2 39 ? 31.686 33.572 19.325 1.00 44.49 ? 39 GLU V OE2 1 ATOM 4239 N N . VAL D 2 40 ? 29.671 34.455 24.921 1.00 33.51 ? 40 VAL V N 1 ATOM 4240 C CA . VAL D 2 40 ? 29.624 35.785 25.535 1.00 32.14 ? 40 VAL V CA 1 ATOM 4241 C C . VAL D 2 40 ? 30.948 36.504 25.664 1.00 31.32 ? 40 VAL V C 1 ATOM 4242 O O . VAL D 2 40 ? 31.943 35.979 26.176 1.00 31.06 ? 40 VAL V O 1 ATOM 4243 C CB . VAL D 2 40 ? 28.861 35.856 26.860 1.00 31.95 ? 40 VAL V CB 1 ATOM 4244 C CG1 . VAL D 2 40 ? 27.851 34.717 26.948 1.00 32.73 ? 40 VAL V CG1 1 ATOM 4245 C CG2 . VAL D 2 40 ? 29.815 35.861 28.016 1.00 31.47 ? 40 VAL V CG2 1 ATOM 4246 N N . VAL D 2 41 ? 30.921 37.732 25.166 1.00 30.46 ? 41 VAL V N 1 ATOM 4247 C CA . VAL D 2 41 ? 32.042 38.634 25.243 1.00 29.50 ? 41 VAL V CA 1 ATOM 4248 C C . VAL D 2 41 ? 31.759 39.759 26.239 1.00 29.35 ? 41 VAL V C 1 ATOM 4249 O O . VAL D 2 41 ? 30.596 40.194 26.391 1.00 29.35 ? 41 VAL V O 1 ATOM 4250 C CB . VAL D 2 41 ? 32.340 39.241 23.906 1.00 28.80 ? 41 VAL V CB 1 ATOM 4251 C CG1 . VAL D 2 41 ? 33.790 39.574 23.845 1.00 28.94 ? 41 VAL V CG1 1 ATOM 4252 C CG2 . VAL D 2 41 ? 31.997 38.273 22.831 1.00 28.41 ? 41 VAL V CG2 1 ATOM 4253 N N . THR D 2 42 ? 32.820 40.182 26.936 1.00 28.52 ? 42 THR V N 1 ATOM 4254 C CA . THR D 2 42 ? 32.806 41.347 27.791 1.00 27.91 ? 42 THR V CA 1 ATOM 4255 C C . THR D 2 42 ? 34.127 42.018 27.577 1.00 27.81 ? 42 THR V C 1 ATOM 4256 O O . THR D 2 42 ? 35.077 41.385 27.130 1.00 27.77 ? 42 THR V O 1 ATOM 4257 C CB . THR D 2 42 ? 32.671 40.995 29.256 1.00 27.90 ? 42 THR V CB 1 ATOM 4258 O OG1 . THR D 2 42 ? 33.752 40.141 29.635 1.00 29.31 ? 42 THR V OG1 1 ATOM 4259 C CG2 . THR D 2 42 ? 31.342 40.324 29.544 1.00 27.12 ? 42 THR V CG2 1 ATOM 4260 N N . ARG D 2 43 ? 34.187 43.307 27.878 1.00 28.19 ? 43 ARG V N 1 ATOM 4261 C CA . ARG D 2 43 ? 35.365 44.109 27.530 1.00 29.02 ? 43 ARG V CA 1 ATOM 4262 C C . ARG D 2 43 ? 35.411 45.412 28.308 1.00 29.64 ? 43 ARG V C 1 ATOM 4263 O O . ARG D 2 43 ? 34.366 45.849 28.816 1.00 30.20 ? 43 ARG V O 1 ATOM 4264 C CB . ARG D 2 43 ? 35.411 44.391 26.026 1.00 28.87 ? 43 ARG V CB 1 ATOM 4265 C CG . ARG D 2 43 ? 34.041 44.573 25.341 1.00 28.11 ? 43 ARG V CG 1 ATOM 4266 C CD . ARG D 2 43 ? 34.250 44.701 23.864 1.00 26.38 ? 43 ARG V CD 1 ATOM 4267 N NE . ARG D 2 43 ? 33.163 44.159 23.075 1.00 26.09 ? 43 ARG V NE 1 ATOM 4268 C CZ . ARG D 2 43 ? 33.345 43.387 22.006 1.00 26.52 ? 43 ARG V CZ 1 ATOM 4269 N NH1 . ARG D 2 43 ? 34.576 43.022 21.624 1.00 23.87 ? 43 ARG V NH1 1 ATOM 4270 N NH2 . ARG D 2 43 ? 32.283 42.948 21.344 1.00 27.29 ? 43 ARG V NH2 1 ATOM 4271 N N . GLY D 2 44 ? 36.606 46.012 28.398 1.00 29.80 ? 44 GLY V N 1 ATOM 4272 C CA . GLY D 2 44 ? 36.848 47.191 29.237 1.00 30.58 ? 44 GLY V CA 1 ATOM 4273 C C . GLY D 2 44 ? 38.326 47.482 29.451 1.00 31.30 ? 44 GLY V C 1 ATOM 4274 O O . GLY D 2 44 ? 39.164 46.995 28.688 1.00 31.27 ? 44 GLY V O 1 ATOM 4275 N N . CYS D 2 45 ? 38.661 48.262 30.485 1.00 31.76 ? 45 CYS V N 1 ATOM 4276 C CA . CYS D 2 45 ? 40.057 48.641 30.711 1.00 32.38 ? 45 CYS V CA 1 ATOM 4277 C C . CYS D 2 45 ? 40.876 47.590 31.500 1.00 32.37 ? 45 CYS V C 1 ATOM 4278 O O . CYS D 2 45 ? 40.306 46.748 32.193 1.00 32.22 ? 45 CYS V O 1 ATOM 4279 C CB . CYS D 2 45 ? 40.121 50.048 31.294 1.00 32.59 ? 45 CYS V CB 1 ATOM 4280 S SG . CYS D 2 45 ? 39.470 51.359 30.114 1.00 35.85 ? 45 CYS V SG 1 ATOM 4281 N N . ALA D 2 46 ? 42.203 47.631 31.394 1.00 32.90 ? 46 ALA V N 1 ATOM 4282 C CA . ALA D 2 46 ? 43.022 46.437 31.666 1.00 34.02 ? 46 ALA V CA 1 ATOM 4283 C C . ALA D 2 46 ? 43.808 46.279 32.971 1.00 35.04 ? 46 ALA V C 1 ATOM 4284 O O . ALA D 2 46 ? 43.571 45.328 33.739 1.00 35.24 ? 46 ALA V O 1 ATOM 4285 C CB . ALA D 2 46 ? 43.962 46.202 30.533 1.00 33.98 ? 46 ALA V CB 1 ATOM 4286 N N . HIS D 2 47 ? 44.768 47.180 33.188 1.00 36.03 ? 47 HIS V N 1 ATOM 4287 C CA . HIS D 2 47 ? 45.891 46.996 34.143 1.00 36.90 ? 47 HIS V CA 1 ATOM 4288 C C . HIS D 2 47 ? 46.936 46.239 33.375 1.00 36.45 ? 47 HIS V C 1 ATOM 4289 O O . HIS D 2 47 ? 46.670 45.162 32.848 1.00 36.58 ? 47 HIS V O 1 ATOM 4290 C CB . HIS D 2 47 ? 45.502 46.258 35.435 1.00 37.43 ? 47 HIS V CB 1 ATOM 4291 C CG . HIS D 2 47 ? 44.412 46.941 36.204 1.00 40.80 ? 47 HIS V CG 1 ATOM 4292 N ND1 . HIS D 2 47 ? 44.604 48.144 36.860 1.00 42.88 ? 47 HIS V ND1 1 ATOM 4293 C CD2 . HIS D 2 47 ? 43.106 46.614 36.386 1.00 42.16 ? 47 HIS V CD2 1 ATOM 4294 C CE1 . HIS D 2 47 ? 43.468 48.516 37.428 1.00 43.17 ? 47 HIS V CE1 1 ATOM 4295 N NE2 . HIS D 2 47 ? 42.544 47.609 37.151 1.00 43.37 ? 47 HIS V NE2 1 ATOM 4296 N N . SER D 2 48 ? 48.116 46.817 33.274 1.00 36.03 ? 48 SER V N 1 ATOM 4297 C CA . SER D 2 48 ? 49.041 46.337 32.293 1.00 36.19 ? 48 SER V CA 1 ATOM 4298 C C . SER D 2 48 ? 49.828 45.184 32.820 1.00 36.14 ? 48 SER V C 1 ATOM 4299 O O . SER D 2 48 ? 50.820 44.799 32.219 1.00 36.10 ? 48 SER V O 1 ATOM 4300 C CB . SER D 2 48 ? 49.970 47.445 31.876 1.00 36.45 ? 48 SER V CB 1 ATOM 4301 O OG . SER D 2 48 ? 50.486 48.039 33.040 1.00 37.86 ? 48 SER V OG 1 ATOM 4302 N N . GLU D 2 49 ? 49.380 44.625 33.939 1.00 36.64 ? 49 GLU V N 1 ATOM 4303 C CA . GLU D 2 49 ? 49.940 43.365 34.454 1.00 37.19 ? 49 GLU V CA 1 ATOM 4304 C C . GLU D 2 49 ? 49.085 42.182 34.003 1.00 37.15 ? 49 GLU V C 1 ATOM 4305 O O . GLU D 2 49 ? 48.807 41.251 34.746 1.00 37.22 ? 49 GLU V O 1 ATOM 4306 C CB . GLU D 2 49 ? 50.120 43.415 35.977 1.00 37.17 ? 49 GLU V CB 1 ATOM 4307 C CG . GLU D 2 49 ? 50.996 44.589 36.456 1.00 38.44 ? 49 GLU V CG 1 ATOM 4308 C CD . GLU D 2 49 ? 52.324 44.740 35.679 1.00 39.35 ? 49 GLU V CD 1 ATOM 4309 O OE1 . GLU D 2 49 ? 52.445 45.669 34.842 1.00 38.49 ? 49 GLU V OE1 1 ATOM 4310 O OE2 . GLU D 2 49 ? 53.245 43.928 35.909 1.00 39.91 ? 49 GLU V OE2 1 ATOM 4311 N N . LYS D 2 50 ? 48.680 42.245 32.746 1.00 37.39 ? 50 LYS V N 1 ATOM 4312 C CA . LYS D 2 50 ? 47.734 41.310 32.187 1.00 37.49 ? 50 LYS V CA 1 ATOM 4313 C C . LYS D 2 50 ? 48.177 40.915 30.790 1.00 37.80 ? 50 LYS V C 1 ATOM 4314 O O . LYS D 2 50 ? 48.784 41.725 30.078 1.00 37.78 ? 50 LYS V O 1 ATOM 4315 C CB . LYS D 2 50 ? 46.348 41.935 32.157 1.00 37.07 ? 50 LYS V CB 1 ATOM 4316 C CG . LYS D 2 50 ? 45.678 41.907 33.493 1.00 36.75 ? 50 LYS V CG 1 ATOM 4317 C CD . LYS D 2 50 ? 44.194 41.923 33.313 1.00 37.69 ? 50 LYS V CD 1 ATOM 4318 C CE . LYS D 2 50 ? 43.726 40.663 32.609 1.00 37.79 ? 50 LYS V CE 1 ATOM 4319 N NZ . LYS D 2 50 ? 42.673 40.955 31.619 1.00 37.62 ? 50 LYS V NZ 1 ATOM 4320 N N . THR D 2 51 ? 47.874 39.669 30.415 1.00 38.17 ? 51 THR V N 1 ATOM 4321 C CA . THR D 2 51 ? 48.338 39.078 29.148 1.00 38.55 ? 51 THR V CA 1 ATOM 4322 C C . THR D 2 51 ? 47.199 38.436 28.356 1.00 39.19 ? 51 THR V C 1 ATOM 4323 O O . THR D 2 51 ? 46.048 38.450 28.799 1.00 39.32 ? 51 THR V O 1 ATOM 4324 C CB . THR D 2 51 ? 49.409 38.015 29.396 1.00 38.16 ? 51 THR V CB 1 ATOM 4325 O OG1 . THR D 2 51 ? 49.039 37.252 30.551 1.00 37.38 ? 51 THR V OG1 1 ATOM 4326 C CG2 . THR D 2 51 ? 50.764 38.658 29.602 1.00 37.38 ? 51 THR V CG2 1 ATOM 4327 N N . ASN D 2 52 ? 47.515 37.902 27.179 1.00 39.67 ? 52 ASN V N 1 ATOM 4328 C CA . ASN D 2 52 ? 46.560 37.089 26.466 1.00 41.02 ? 52 ASN V CA 1 ATOM 4329 C C . ASN D 2 52 ? 46.476 35.732 27.173 1.00 40.95 ? 52 ASN V C 1 ATOM 4330 O O . ASN D 2 52 ? 47.499 35.224 27.603 1.00 41.39 ? 52 ASN V O 1 ATOM 4331 C CB . ASN D 2 52 ? 47.019 36.916 25.024 1.00 41.72 ? 52 ASN V CB 1 ATOM 4332 C CG . ASN D 2 52 ? 46.927 38.202 24.202 1.00 45.32 ? 52 ASN V CG 1 ATOM 4333 O OD1 . ASN D 2 52 ? 46.266 39.173 24.587 1.00 46.04 ? 52 ASN V OD1 1 ATOM 4334 N ND2 . ASN D 2 52 ? 47.597 38.200 23.053 1.00 50.56 ? 52 ASN V ND2 1 ATOM 4335 N N . ARG D 2 53 ? 45.287 35.144 27.313 1.00 41.00 ? 53 ARG V N 1 ATOM 4336 C CA . ARG D 2 53 ? 45.158 33.829 27.969 1.00 41.11 ? 53 ARG V CA 1 ATOM 4337 C C . ARG D 2 53 ? 43.968 32.961 27.537 1.00 41.53 ? 53 ARG V C 1 ATOM 4338 O O . ARG D 2 53 ? 42.904 33.459 27.209 1.00 42.02 ? 53 ARG V O 1 ATOM 4339 C CB . ARG D 2 53 ? 45.174 33.981 29.492 1.00 41.09 ? 53 ARG V CB 1 ATOM 4340 C CG . ARG D 2 53 ? 43.925 34.573 30.130 1.00 40.64 ? 53 ARG V CG 1 ATOM 4341 C CD . ARG D 2 53 ? 44.114 36.019 30.515 1.00 40.15 ? 53 ARG V CD 1 ATOM 4342 N NE . ARG D 2 53 ? 45.263 36.264 31.397 1.00 39.45 ? 53 ARG V NE 1 ATOM 4343 C CZ . ARG D 2 53 ? 45.186 36.864 32.585 1.00 38.74 ? 53 ARG V CZ 1 ATOM 4344 N NH1 . ARG D 2 53 ? 44.013 37.274 33.061 1.00 37.67 ? 53 ARG V NH1 1 ATOM 4345 N NH2 . ARG D 2 53 ? 46.286 37.061 33.298 1.00 37.56 ? 53 ARG V NH2 1 ATOM 4346 N N . THR D 2 54 ? 44.155 31.653 27.545 1.00 41.91 ? 54 THR V N 1 ATOM 4347 C CA . THR D 2 54 ? 43.096 30.729 27.162 1.00 42.51 ? 54 THR V CA 1 ATOM 4348 C C . THR D 2 54 ? 42.868 29.773 28.299 1.00 42.64 ? 54 THR V C 1 ATOM 4349 O O . THR D 2 54 ? 43.739 29.595 29.139 1.00 43.60 ? 54 THR V O 1 ATOM 4350 C CB . THR D 2 54 ? 43.532 29.806 26.015 1.00 42.78 ? 54 THR V CB 1 ATOM 4351 O OG1 . THR D 2 54 ? 44.772 30.257 25.454 1.00 43.26 ? 54 THR V OG1 1 ATOM 4352 C CG2 . THR D 2 54 ? 42.425 29.669 24.944 1.00 43.16 ? 54 THR V CG2 1 ATOM 4353 N N . MET D 2 55 ? 41.717 29.123 28.308 1.00 42.41 ? 55 MET V N 1 ATOM 4354 C CA . MET D 2 55 ? 41.466 27.994 29.194 1.00 42.39 ? 55 MET V CA 1 ATOM 4355 C C . MET D 2 55 ? 40.389 27.243 28.447 1.00 41.46 ? 55 MET V C 1 ATOM 4356 O O . MET D 2 55 ? 39.765 27.818 27.548 1.00 42.14 ? 55 MET V O 1 ATOM 4357 C CB . MET D 2 55 ? 40.964 28.477 30.551 1.00 43.09 ? 55 MET V CB 1 ATOM 4358 C CG . MET D 2 55 ? 41.044 27.458 31.694 1.00 46.55 ? 55 MET V CG 1 ATOM 4359 S SD . MET D 2 55 ? 40.174 27.979 33.234 1.00 53.86 ? 55 MET V SD 1 ATOM 4360 C CE . MET D 2 55 ? 41.279 29.265 33.866 1.00 51.91 ? 55 MET V CE 1 ATOM 4361 N N . SER D 2 56 ? 40.182 25.968 28.760 1.00 39.76 ? 56 SER V N 1 ATOM 4362 C CA . SER D 2 56 ? 39.208 25.158 28.024 1.00 38.08 ? 56 SER V CA 1 ATOM 4363 C C . SER D 2 56 ? 39.096 23.837 28.722 1.00 37.15 ? 56 SER V C 1 ATOM 4364 O O . SER D 2 56 ? 40.099 23.153 28.947 1.00 37.51 ? 56 SER V O 1 ATOM 4365 C CB . SER D 2 56 ? 39.644 24.907 26.580 1.00 37.78 ? 56 SER V CB 1 ATOM 4366 O OG . SER D 2 56 ? 40.524 25.916 26.111 1.00 37.46 ? 56 SER V OG 1 ATOM 4367 N N . TYR D 2 57 ? 37.883 23.478 29.088 1.00 35.47 ? 57 TYR V N 1 ATOM 4368 C CA . TYR D 2 57 ? 37.663 22.196 29.707 1.00 34.04 ? 57 TYR V CA 1 ATOM 4369 C C . TYR D 2 57 ? 36.328 21.710 29.206 1.00 33.82 ? 57 TYR V C 1 ATOM 4370 O O . TYR D 2 57 ? 35.640 22.447 28.481 1.00 33.83 ? 57 TYR V O 1 ATOM 4371 C CB . TYR D 2 57 ? 37.703 22.303 31.234 1.00 33.42 ? 57 TYR V CB 1 ATOM 4372 C CG . TYR D 2 57 ? 36.619 23.168 31.831 1.00 31.69 ? 57 TYR V CG 1 ATOM 4373 C CD1 . TYR D 2 57 ? 35.448 22.608 32.331 1.00 30.33 ? 57 TYR V CD1 1 ATOM 4374 C CD2 . TYR D 2 57 ? 36.763 24.549 31.903 1.00 30.33 ? 57 TYR V CD2 1 ATOM 4375 C CE1 . TYR D 2 57 ? 34.448 23.413 32.876 1.00 29.13 ? 57 TYR V CE1 1 ATOM 4376 C CE2 . TYR D 2 57 ? 35.764 25.355 32.446 1.00 27.84 ? 57 TYR V CE2 1 ATOM 4377 C CZ . TYR D 2 57 ? 34.622 24.783 32.923 1.00 27.15 ? 57 TYR V CZ 1 ATOM 4378 O OH . TYR D 2 57 ? 33.653 25.573 33.460 1.00 26.40 ? 57 TYR V OH 1 ATOM 4379 N N . ARG D 2 58 ? 35.963 20.480 29.573 1.00 33.12 ? 58 ARG V N 1 ATOM 4380 C CA . ARG D 2 58 ? 34.688 19.936 29.140 1.00 32.45 ? 58 ARG V CA 1 ATOM 4381 C C . ARG D 2 58 ? 33.826 19.320 30.238 1.00 31.66 ? 58 ARG V C 1 ATOM 4382 O O . ARG D 2 58 ? 34.349 18.742 31.182 1.00 31.47 ? 58 ARG V O 1 ATOM 4383 C CB . ARG D 2 58 ? 34.855 19.010 27.917 1.00 32.89 ? 58 ARG V CB 1 ATOM 4384 C CG . ARG D 2 58 ? 35.717 17.763 28.068 1.00 33.06 ? 58 ARG V CG 1 ATOM 4385 C CD . ARG D 2 58 ? 35.061 16.619 27.258 1.00 33.66 ? 58 ARG V CD 1 ATOM 4386 N NE . ARG D 2 58 ? 35.807 16.173 26.080 1.00 32.84 ? 58 ARG V NE 1 ATOM 4387 C CZ . ARG D 2 58 ? 35.250 15.606 25.010 1.00 32.21 ? 58 ARG V CZ 1 ATOM 4388 N NH1 . ARG D 2 58 ? 33.935 15.434 24.941 1.00 31.68 ? 58 ARG V NH1 1 ATOM 4389 N NH2 . ARG D 2 58 ? 36.010 15.228 23.996 1.00 31.96 ? 58 ARG V NH2 1 ATOM 4390 N N . MET D 2 59 ? 32.507 19.468 30.075 1.00 30.86 ? 59 MET V N 1 ATOM 4391 C CA . MET D 2 59 ? 31.482 18.949 30.972 1.00 30.14 ? 59 MET V CA 1 ATOM 4392 C C . MET D 2 59 ? 30.551 17.998 30.247 1.00 29.26 ? 59 MET V C 1 ATOM 4393 O O . MET D 2 59 ? 29.421 18.340 29.914 1.00 29.00 ? 59 MET V O 1 ATOM 4394 C CB . MET D 2 59 ? 30.637 20.088 31.498 1.00 30.53 ? 59 MET V CB 1 ATOM 4395 C CG . MET D 2 59 ? 31.161 20.814 32.714 1.00 32.76 ? 59 MET V CG 1 ATOM 4396 S SD . MET D 2 59 ? 29.775 21.777 33.416 1.00 37.53 ? 59 MET V SD 1 ATOM 4397 C CE . MET D 2 59 ? 28.944 20.521 34.397 1.00 37.36 ? 59 MET V CE 1 ATOM 4398 N N . GLY D 2 60 ? 31.037 16.786 30.001 1.00 28.91 ? 60 GLY V N 1 ATOM 4399 C CA . GLY D 2 60 ? 30.254 15.775 29.315 1.00 28.89 ? 60 GLY V CA 1 ATOM 4400 C C . GLY D 2 60 ? 30.278 15.944 27.809 1.00 28.90 ? 60 GLY V C 1 ATOM 4401 O O . GLY D 2 60 ? 31.283 15.660 27.158 1.00 29.18 ? 60 GLY V O 1 ATOM 4402 N N . SER D 2 61 ? 29.163 16.409 27.254 1.00 28.33 ? 61 SER V N 1 ATOM 4403 C CA . SER D 2 61 ? 29.053 16.617 25.815 1.00 27.75 ? 61 SER V CA 1 ATOM 4404 C C . SER D 2 61 ? 29.361 18.062 25.440 1.00 27.58 ? 61 SER V C 1 ATOM 4405 O O . SER D 2 61 ? 29.540 18.384 24.265 1.00 27.43 ? 61 SER V O 1 ATOM 4406 C CB . SER D 2 61 ? 27.656 16.232 25.324 1.00 28.01 ? 61 SER V CB 1 ATOM 4407 O OG . SER D 2 61 ? 26.711 17.241 25.635 1.00 27.40 ? 61 SER V OG 1 ATOM 4408 N N . MET D 2 62 ? 29.421 18.930 26.445 1.00 27.71 ? 62 MET V N 1 ATOM 4409 C CA . MET D 2 62 ? 29.707 20.342 26.222 1.00 28.07 ? 62 MET V CA 1 ATOM 4410 C C . MET D 2 62 ? 31.179 20.652 26.466 1.00 28.02 ? 62 MET V C 1 ATOM 4411 O O . MET D 2 62 ? 31.784 20.140 27.408 1.00 28.55 ? 62 MET V O 1 ATOM 4412 C CB . MET D 2 62 ? 28.829 21.215 27.122 1.00 27.95 ? 62 MET V CB 1 ATOM 4413 C CG . MET D 2 62 ? 29.300 22.655 27.239 1.00 29.02 ? 62 MET V CG 1 ATOM 4414 S SD . MET D 2 62 ? 28.118 23.705 28.106 1.00 33.55 ? 62 MET V SD 1 ATOM 4415 C CE . MET D 2 62 ? 26.922 24.011 26.809 1.00 32.57 ? 62 MET V CE 1 ATOM 4416 N N . ILE D 2 63 ? 31.751 21.495 25.612 1.00 27.79 ? 63 ILE V N 1 ATOM 4417 C CA . ILE D 2 63 ? 33.154 21.876 25.734 1.00 27.67 ? 63 ILE V CA 1 ATOM 4418 C C . ILE D 2 63 ? 33.105 23.353 25.954 1.00 27.74 ? 63 ILE V C 1 ATOM 4419 O O . ILE D 2 63 ? 32.444 24.065 25.198 1.00 27.97 ? 63 ILE V O 1 ATOM 4420 C CB . ILE D 2 63 ? 33.964 21.634 24.468 1.00 27.67 ? 63 ILE V CB 1 ATOM 4421 C CG1 . ILE D 2 63 ? 33.982 20.147 24.083 1.00 29.10 ? 63 ILE V CG1 1 ATOM 4422 C CG2 . ILE D 2 63 ? 35.369 22.131 24.654 1.00 27.15 ? 63 ILE V CG2 1 ATOM 4423 C CD1 . ILE D 2 63 ? 33.036 19.736 22.895 1.00 30.33 ? 63 ILE V CD1 1 ATOM 4424 N N . ILE D 2 64 ? 33.766 23.830 27.001 1.00 27.72 ? 64 ILE V N 1 ATOM 4425 C CA . ILE D 2 64 ? 33.686 25.251 27.291 1.00 27.47 ? 64 ILE V CA 1 ATOM 4426 C C . ILE D 2 64 ? 35.033 25.929 27.035 1.00 27.51 ? 64 ILE V C 1 ATOM 4427 O O . ILE D 2 64 ? 36.082 25.381 27.392 1.00 27.78 ? 64 ILE V O 1 ATOM 4428 C CB . ILE D 2 64 ? 33.080 25.535 28.675 1.00 27.14 ? 64 ILE V CB 1 ATOM 4429 C CG1 . ILE D 2 64 ? 34.163 25.822 29.681 1.00 28.33 ? 64 ILE V CG1 1 ATOM 4430 C CG2 . ILE D 2 64 ? 32.158 24.417 29.131 1.00 26.40 ? 64 ILE V CG2 1 ATOM 4431 C CD1 . ILE D 2 64 ? 34.488 27.289 29.766 1.00 30.23 ? 64 ILE V CD1 1 ATOM 4432 N N . SER D 2 65 ? 35.002 27.093 26.381 1.00 27.37 ? 65 SER V N 1 ATOM 4433 C CA . SER D 2 65 ? 36.225 27.668 25.848 1.00 27.32 ? 65 SER V CA 1 ATOM 4434 C C . SER D 2 65 ? 36.425 29.162 26.035 1.00 27.43 ? 65 SER V C 1 ATOM 4435 O O . SER D 2 65 ? 35.871 29.980 25.301 1.00 26.70 ? 65 SER V O 1 ATOM 4436 C CB . SER D 2 65 ? 36.402 27.293 24.393 1.00 27.30 ? 65 SER V CB 1 ATOM 4437 O OG . SER D 2 65 ? 37.700 27.652 23.973 1.00 27.92 ? 65 SER V OG 1 ATOM 4438 N N . LEU D 2 66 ? 37.282 29.465 27.017 1.00 28.17 ? 66 LEU V N 1 ATOM 4439 C CA . LEU D 2 66 ? 37.630 30.810 27.455 1.00 28.72 ? 66 LEU V CA 1 ATOM 4440 C C . LEU D 2 66 ? 38.867 31.319 26.816 1.00 29.08 ? 66 LEU V C 1 ATOM 4441 O O . LEU D 2 66 ? 39.874 30.624 26.756 1.00 29.34 ? 66 LEU V O 1 ATOM 4442 C CB . LEU D 2 66 ? 37.870 30.849 28.947 1.00 28.45 ? 66 LEU V CB 1 ATOM 4443 C CG . LEU D 2 66 ? 36.576 31.241 29.624 1.00 30.03 ? 66 LEU V CG 1 ATOM 4444 C CD1 . LEU D 2 66 ? 35.908 30.022 30.201 1.00 31.21 ? 66 LEU V CD1 1 ATOM 4445 C CD2 . LEU D 2 66 ? 36.839 32.230 30.712 1.00 32.13 ? 66 LEU V CD2 1 ATOM 4446 N N . THR D 2 67 ? 38.778 32.558 26.358 1.00 29.72 ? 67 THR V N 1 ATOM 4447 C CA . THR D 2 67 ? 39.901 33.275 25.790 1.00 30.46 ? 67 THR V CA 1 ATOM 4448 C C . THR D 2 67 ? 39.755 34.722 26.183 1.00 30.72 ? 67 THR V C 1 ATOM 4449 O O . THR D 2 67 ? 38.641 35.253 26.205 1.00 30.85 ? 67 THR V O 1 ATOM 4450 C CB . THR D 2 67 ? 39.967 33.175 24.244 1.00 30.77 ? 67 THR V CB 1 ATOM 4451 O OG1 . THR D 2 67 ? 40.274 34.472 23.700 1.00 31.60 ? 67 THR V OG1 1 ATOM 4452 C CG2 . THR D 2 67 ? 38.629 32.647 23.634 1.00 30.89 ? 67 THR V CG2 1 ATOM 4453 N N . GLU D 2 68 ? 40.880 35.353 26.497 1.00 30.98 ? 68 GLU V N 1 ATOM 4454 C CA . GLU D 2 68 ? 40.898 36.761 26.852 1.00 31.56 ? 68 GLU V CA 1 ATOM 4455 C C . GLU D 2 68 ? 42.115 37.353 26.219 1.00 31.87 ? 68 GLU V C 1 ATOM 4456 O O . GLU D 2 68 ? 43.119 36.669 26.104 1.00 32.16 ? 68 GLU V O 1 ATOM 4457 C CB . GLU D 2 68 ? 40.999 36.941 28.345 1.00 31.53 ? 68 GLU V CB 1 ATOM 4458 C CG . GLU D 2 68 ? 40.856 38.366 28.762 1.00 32.34 ? 68 GLU V CG 1 ATOM 4459 C CD . GLU D 2 68 ? 41.101 38.554 30.231 1.00 34.60 ? 68 GLU V CD 1 ATOM 4460 O OE1 . GLU D 2 68 ? 40.096 38.745 30.980 1.00 34.85 ? 68 GLU V OE1 1 ATOM 4461 O OE2 . GLU D 2 68 ? 42.299 38.494 30.629 1.00 34.93 ? 68 GLU V OE2 1 ATOM 4462 N N . THR D 2 69 ? 42.037 38.614 25.798 1.00 32.37 ? 69 THR V N 1 ATOM 4463 C CA . THR D 2 69 ? 43.145 39.210 25.053 1.00 32.74 ? 69 THR V CA 1 ATOM 4464 C C . THR D 2 69 ? 43.278 40.688 25.233 1.00 33.04 ? 69 THR V C 1 ATOM 4465 O O . THR D 2 69 ? 42.294 41.431 25.094 1.00 33.51 ? 69 THR V O 1 ATOM 4466 C CB . THR D 2 69 ? 43.030 38.979 23.558 1.00 32.86 ? 69 THR V CB 1 ATOM 4467 O OG1 . THR D 2 69 ? 44.181 39.558 22.933 1.00 32.66 ? 69 THR V OG1 1 ATOM 4468 C CG2 . THR D 2 69 ? 41.734 39.611 23.012 1.00 32.38 ? 69 THR V CG2 1 ATOM 4469 N N . VAL D 2 70 ? 44.505 41.115 25.507 1.00 33.05 ? 70 VAL V N 1 ATOM 4470 C CA . VAL D 2 70 ? 44.729 42.508 25.817 1.00 33.33 ? 70 VAL V CA 1 ATOM 4471 C C . VAL D 2 70 ? 45.576 43.213 24.791 1.00 34.09 ? 70 VAL V C 1 ATOM 4472 O O . VAL D 2 70 ? 46.710 42.829 24.528 1.00 34.42 ? 70 VAL V O 1 ATOM 4473 C CB . VAL D 2 70 ? 45.259 42.750 27.249 1.00 32.79 ? 70 VAL V CB 1 ATOM 4474 C CG1 . VAL D 2 70 ? 44.143 42.580 28.238 1.00 32.91 ? 70 VAL V CG1 1 ATOM 4475 C CG2 . VAL D 2 70 ? 46.385 41.850 27.574 1.00 32.13 ? 70 VAL V CG2 1 ATOM 4476 N N . CYS D 2 71 ? 44.991 44.251 24.214 1.00 34.87 ? 71 CYS V N 1 ATOM 4477 C CA . CYS D 2 71 ? 45.652 45.082 23.244 1.00 36.12 ? 71 CYS V CA 1 ATOM 4478 C C . CYS D 2 71 ? 46.062 46.420 23.880 1.00 36.10 ? 71 CYS V C 1 ATOM 4479 O O . CYS D 2 71 ? 45.486 46.818 24.907 1.00 36.30 ? 71 CYS V O 1 ATOM 4480 C CB . CYS D 2 71 ? 44.685 45.330 22.106 1.00 36.39 ? 71 CYS V CB 1 ATOM 4481 S SG . CYS D 2 71 ? 44.743 47.029 21.642 1.00 40.44 ? 71 CYS V SG 1 ATOM 4482 N N . ALA D 2 72 ? 47.029 47.119 23.264 1.00 36.03 ? 72 ALA V N 1 ATOM 4483 C CA . ALA D 2 72 ? 47.517 48.420 23.787 1.00 35.80 ? 72 ALA V CA 1 ATOM 4484 C C . ALA D 2 72 ? 46.975 49.653 23.058 1.00 35.53 ? 72 ALA V C 1 ATOM 4485 O O . ALA D 2 72 ? 46.835 50.713 23.648 1.00 35.70 ? 72 ALA V O 1 ATOM 4486 C CB . ALA D 2 72 ? 49.066 48.462 23.863 1.00 35.54 ? 72 ALA V CB 1 ATOM 4487 N N . THR D 2 73 ? 46.671 49.520 21.779 1.00 35.38 ? 73 THR V N 1 ATOM 4488 C CA . THR D 2 73 ? 46.196 50.652 21.002 1.00 35.42 ? 73 THR V CA 1 ATOM 4489 C C . THR D 2 73 ? 44.850 51.188 21.486 1.00 35.49 ? 73 THR V C 1 ATOM 4490 O O . THR D 2 73 ? 44.162 50.535 22.260 1.00 35.47 ? 73 THR V O 1 ATOM 4491 C CB . THR D 2 73 ? 46.095 50.309 19.502 1.00 35.50 ? 73 THR V CB 1 ATOM 4492 O OG1 . THR D 2 73 ? 44.794 50.685 19.014 1.00 36.31 ? 73 THR V OG1 1 ATOM 4493 C CG2 . THR D 2 73 ? 46.322 48.808 19.238 1.00 35.28 ? 73 THR V CG2 1 ATOM 4494 N N . ASN D 2 74 ? 44.500 52.381 21.002 1.00 35.79 ? 74 ASN V N 1 ATOM 4495 C CA . ASN D 2 74 ? 43.207 53.042 21.240 1.00 36.07 ? 74 ASN V CA 1 ATOM 4496 C C . ASN D 2 74 ? 42.006 52.370 20.630 1.00 35.94 ? 74 ASN V C 1 ATOM 4497 O O . ASN D 2 74 ? 42.090 51.849 19.520 1.00 36.31 ? 74 ASN V O 1 ATOM 4498 C CB . ASN D 2 74 ? 43.233 54.474 20.704 1.00 36.20 ? 74 ASN V CB 1 ATOM 4499 C CG . ASN D 2 74 ? 43.104 55.500 21.801 1.00 37.36 ? 74 ASN V CG 1 ATOM 4500 O OD1 . ASN D 2 74 ? 42.485 55.245 22.846 1.00 39.20 ? 74 ASN V OD1 1 ATOM 4501 N ND2 . ASN D 2 74 ? 43.689 56.671 21.580 1.00 37.54 ? 74 ASN V ND2 1 ATOM 4502 N N . LEU D 2 75 ? 40.886 52.449 21.348 1.00 35.72 ? 75 LEU V N 1 ATOM 4503 C CA . LEU D 2 75 ? 39.602 51.854 20.967 1.00 35.75 ? 75 LEU V CA 1 ATOM 4504 C C . LEU D 2 75 ? 39.726 50.534 20.253 1.00 36.40 ? 75 LEU V C 1 ATOM 4505 O O . LEU D 2 75 ? 38.965 50.235 19.340 1.00 36.57 ? 75 LEU V O 1 ATOM 4506 C CB . LEU D 2 75 ? 38.770 52.812 20.131 1.00 35.09 ? 75 LEU V CB 1 ATOM 4507 C CG . LEU D 2 75 ? 37.880 53.729 20.950 1.00 34.94 ? 75 LEU V CG 1 ATOM 4508 C CD1 . LEU D 2 75 ? 36.778 54.252 20.089 1.00 35.17 ? 75 LEU V CD1 1 ATOM 4509 C CD2 . LEU D 2 75 ? 37.285 52.996 22.126 1.00 36.21 ? 75 LEU V CD2 1 ATOM 4510 N N . CYS D 2 76 ? 40.675 49.729 20.690 1.00 37.23 ? 76 CYS V N 1 ATOM 4511 C CA . CYS D 2 76 ? 41.114 48.634 19.869 1.00 38.58 ? 76 CYS V CA 1 ATOM 4512 C C . CYS D 2 76 ? 40.325 47.355 20.107 1.00 39.10 ? 76 CYS V C 1 ATOM 4513 O O . CYS D 2 76 ? 40.617 46.323 19.480 1.00 39.55 ? 76 CYS V O 1 ATOM 4514 C CB . CYS D 2 76 ? 42.582 48.380 20.141 1.00 38.53 ? 76 CYS V CB 1 ATOM 4515 S SG . CYS D 2 76 ? 42.820 47.634 21.757 1.00 40.92 ? 76 CYS V SG 1 ATOM 4516 N N . ASN D 2 77 ? 39.341 47.401 21.002 1.00 39.51 ? 77 ASN V N 1 ATOM 4517 C CA . ASN D 2 77 ? 38.700 46.165 21.421 1.00 39.89 ? 77 ASN V CA 1 ATOM 4518 C C . ASN D 2 77 ? 37.209 46.026 21.108 1.00 40.75 ? 77 ASN V C 1 ATOM 4519 O O . ASN D 2 77 ? 36.390 45.900 22.007 1.00 40.56 ? 77 ASN V O 1 ATOM 4520 C CB . ASN D 2 77 ? 39.048 45.843 22.885 1.00 39.60 ? 77 ASN V CB 1 ATOM 4521 C CG . ASN D 2 77 ? 38.566 46.901 23.876 1.00 38.25 ? 77 ASN V CG 1 ATOM 4522 O OD1 . ASN D 2 77 ? 37.898 47.855 23.535 1.00 35.91 ? 77 ASN V OD1 1 ATOM 4523 N ND2 . ASN D 2 77 ? 38.897 46.697 25.126 1.00 38.52 ? 77 ASN V ND2 1 ATOM 4524 N N . ARG D 2 78 ? 36.873 46.013 19.818 1.00 42.17 ? 78 ARG V N 1 ATOM 4525 C CA . ARG D 2 78 ? 35.478 45.849 19.379 1.00 43.45 ? 78 ARG V CA 1 ATOM 4526 C C . ARG D 2 78 ? 35.146 44.448 18.777 1.00 45.29 ? 78 ARG V C 1 ATOM 4527 O O . ARG D 2 78 ? 35.411 43.418 19.423 1.00 46.00 ? 78 ARG V O 1 ATOM 4528 C CB . ARG D 2 78 ? 35.123 46.974 18.443 1.00 42.61 ? 78 ARG V CB 1 ATOM 4529 C CG . ARG D 2 78 ? 36.150 48.053 18.498 1.00 40.80 ? 78 ARG V CG 1 ATOM 4530 C CD . ARG D 2 78 ? 36.059 48.943 17.291 1.00 39.18 ? 78 ARG V CD 1 ATOM 4531 N NE . ARG D 2 78 ? 37.378 49.441 16.924 1.00 37.42 ? 78 ARG V NE 1 ATOM 4532 C CZ . ARG D 2 78 ? 37.597 50.349 15.986 1.00 35.96 ? 78 ARG V CZ 1 ATOM 4533 N NH1 . ARG D 2 78 ? 36.570 50.861 15.327 1.00 35.59 ? 78 ARG V NH1 1 ATOM 4534 N NH2 . ARG D 2 78 ? 38.838 50.741 15.713 1.00 35.24 ? 78 ARG V NH2 1 ATOM 4535 N N . PRO D 2 79 ? 34.726 44.394 17.500 1.00 46.59 ? 79 PRO V N 1 ATOM 4536 C CA . PRO D 2 79 ? 33.637 43.582 16.917 1.00 47.61 ? 79 PRO V CA 1 ATOM 4537 C C . PRO D 2 79 ? 33.650 42.052 17.235 1.00 48.56 ? 79 PRO V C 1 ATOM 4538 O O . PRO D 2 79 ? 33.379 41.651 18.391 1.00 48.82 ? 79 PRO V O 1 ATOM 4539 C CB . PRO D 2 79 ? 33.829 43.817 15.413 1.00 47.83 ? 79 PRO V CB 1 ATOM 4540 C CG . PRO D 2 79 ? 35.375 43.831 15.270 1.00 47.69 ? 79 PRO V CG 1 ATOM 4541 C CD . PRO D 2 79 ? 35.915 44.372 16.610 1.00 46.74 ? 79 PRO V CD 1 ATOM 4542 N N . ARG D 2 80 ? 33.924 41.220 16.211 1.00 49.09 ? 80 ARG V N 1 ATOM 4543 C CA . ARG D 2 80 ? 34.097 39.763 16.366 1.00 49.37 ? 80 ARG V CA 1 ATOM 4544 C C . ARG D 2 80 ? 34.884 39.500 17.659 1.00 49.75 ? 80 ARG V C 1 ATOM 4545 O O . ARG D 2 80 ? 35.895 40.161 17.900 1.00 49.81 ? 80 ARG V O 1 ATOM 4546 C CB . ARG D 2 80 ? 34.821 39.140 15.147 1.00 49.39 ? 80 ARG V CB 1 ATOM 4547 C CG . ARG D 2 80 ? 33.919 38.414 14.115 1.00 48.62 ? 80 ARG V CG 1 ATOM 4548 C CD . ARG D 2 80 ? 34.729 37.728 13.009 1.00 46.91 ? 80 ARG V CD 1 ATOM 4549 N NE . ARG D 2 80 ? 33.933 37.525 11.792 1.00 46.85 ? 80 ARG V NE 1 ATOM 4550 C CZ . ARG D 2 80 ? 34.430 37.292 10.569 1.00 46.48 ? 80 ARG V CZ 1 ATOM 4551 N NH1 . ARG D 2 80 ? 35.740 37.223 10.356 1.00 45.62 ? 80 ARG V NH1 1 ATOM 4552 N NH2 . ARG D 2 80 ? 33.611 37.131 9.538 1.00 46.21 ? 80 ARG V NH2 1 ATOM 4553 N N . PRO D 2 81 ? 34.410 38.547 18.497 1.00 49.97 ? 81 PRO V N 1 ATOM 4554 C CA . PRO D 2 81 ? 34.855 38.356 19.884 1.00 49.67 ? 81 PRO V CA 1 ATOM 4555 C C . PRO D 2 81 ? 36.341 38.058 20.026 1.00 49.58 ? 81 PRO V C 1 ATOM 4556 O O . PRO D 2 81 ? 36.935 37.473 19.125 1.00 49.70 ? 81 PRO V O 1 ATOM 4557 C CB . PRO D 2 81 ? 34.041 37.142 20.332 1.00 49.66 ? 81 PRO V CB 1 ATOM 4558 C CG . PRO D 2 81 ? 32.844 37.149 19.454 1.00 49.55 ? 81 PRO V CG 1 ATOM 4559 C CD . PRO D 2 81 ? 33.389 37.542 18.131 1.00 50.15 ? 81 PRO V CD 1 ATOM 4560 N N . TYR D 2 93 ? 50.513 19.712 20.416 1.00 37.60 ? 93 TYR V N 1 ATOM 4561 C CA . TYR D 2 93 ? 49.081 19.519 20.258 1.00 37.49 ? 93 TYR V CA 1 ATOM 4562 C C . TYR D 2 93 ? 48.474 18.967 21.550 1.00 37.02 ? 93 TYR V C 1 ATOM 4563 O O . TYR D 2 93 ? 47.310 19.244 21.858 1.00 36.98 ? 93 TYR V O 1 ATOM 4564 C CB . TYR D 2 93 ? 48.793 18.594 19.076 1.00 37.86 ? 93 TYR V CB 1 ATOM 4565 C CG . TYR D 2 93 ? 47.655 19.062 18.194 1.00 39.66 ? 93 TYR V CG 1 ATOM 4566 C CD1 . TYR D 2 93 ? 46.738 20.019 18.657 1.00 40.71 ? 93 TYR V CD1 1 ATOM 4567 C CD2 . TYR D 2 93 ? 47.478 18.540 16.897 1.00 40.93 ? 93 TYR V CD2 1 ATOM 4568 C CE1 . TYR D 2 93 ? 45.671 20.458 17.863 1.00 41.60 ? 93 TYR V CE1 1 ATOM 4569 C CE2 . TYR D 2 93 ? 46.406 18.976 16.085 1.00 41.96 ? 93 TYR V CE2 1 ATOM 4570 C CZ . TYR D 2 93 ? 45.506 19.938 16.586 1.00 42.48 ? 93 TYR V CZ 1 ATOM 4571 O OH . TYR D 2 93 ? 44.447 20.393 15.826 1.00 42.93 ? 93 TYR V OH 1 ATOM 4572 N N . LEU D 2 94 ? 49.274 18.170 22.266 1.00 36.38 ? 94 LEU V N 1 ATOM 4573 C CA . LEU D 2 94 ? 49.082 17.789 23.681 1.00 35.85 ? 94 LEU V CA 1 ATOM 4574 C C . LEU D 2 94 ? 47.673 17.435 24.174 1.00 36.02 ? 94 LEU V C 1 ATOM 4575 O O . LEU D 2 94 ? 46.748 18.254 24.113 1.00 36.10 ? 94 LEU V O 1 ATOM 4576 C CB . LEU D 2 94 ? 49.690 18.858 24.596 1.00 35.47 ? 94 LEU V CB 1 ATOM 4577 C CG . LEU D 2 94 ? 50.112 18.411 25.989 1.00 34.52 ? 94 LEU V CG 1 ATOM 4578 C CD1 . LEU D 2 94 ? 51.241 17.418 25.873 1.00 34.08 ? 94 LEU V CD1 1 ATOM 4579 C CD2 . LEU D 2 94 ? 50.547 19.594 26.797 1.00 33.16 ? 94 LEU V CD2 1 ATOM 4580 N N . GLU D 2 95 ? 47.539 16.216 24.698 1.00 36.15 ? 95 GLU V N 1 ATOM 4581 C CA . GLU D 2 95 ? 46.285 15.731 25.298 1.00 36.24 ? 95 GLU V CA 1 ATOM 4582 C C . GLU D 2 95 ? 46.303 15.783 26.830 1.00 36.01 ? 95 GLU V C 1 ATOM 4583 O O . GLU D 2 95 ? 47.260 15.331 27.454 1.00 35.98 ? 95 GLU V O 1 ATOM 4584 C CB . GLU D 2 95 ? 45.993 14.295 24.855 1.00 36.35 ? 95 GLU V CB 1 ATOM 4585 C CG . GLU D 2 95 ? 44.716 13.709 25.484 1.00 36.99 ? 95 GLU V CG 1 ATOM 4586 C CD . GLU D 2 95 ? 44.593 12.199 25.329 1.00 37.50 ? 95 GLU V CD 1 ATOM 4587 O OE1 . GLU D 2 95 ? 43.500 11.677 25.646 1.00 37.39 ? 95 GLU V OE1 1 ATOM 4588 O OE2 . GLU D 2 95 ? 45.575 11.541 24.901 1.00 37.19 ? 95 GLU V OE2 1 ATOM 4589 N N . CYS D 2 96 ? 45.232 16.308 27.425 1.00 35.76 ? 96 CYS V N 1 ATOM 4590 C CA . CYS D 2 96 ? 45.137 16.424 28.875 1.00 35.54 ? 96 CYS V CA 1 ATOM 4591 C C . CYS D 2 96 ? 43.908 15.770 29.430 1.00 35.42 ? 96 CYS V C 1 ATOM 4592 O O . CYS D 2 96 ? 42.966 15.466 28.709 1.00 35.37 ? 96 CYS V O 1 ATOM 4593 C CB . CYS D 2 96 ? 45.106 17.882 29.288 1.00 35.36 ? 96 CYS V CB 1 ATOM 4594 S SG . CYS D 2 96 ? 46.335 18.814 28.445 1.00 36.16 ? 96 CYS V SG 1 ATOM 4595 N N . ALA D 2 97 ? 43.929 15.571 30.740 1.00 35.34 ? 97 ALA V N 1 ATOM 4596 C CA . ALA D 2 97 ? 42.739 15.207 31.471 1.00 35.28 ? 97 ALA V CA 1 ATOM 4597 C C . ALA D 2 97 ? 41.888 16.447 31.533 1.00 35.09 ? 97 ALA V C 1 ATOM 4598 O O . ALA D 2 97 ? 42.411 17.552 31.443 1.00 35.09 ? 97 ALA V O 1 ATOM 4599 C CB . ALA D 2 97 ? 43.100 14.770 32.859 1.00 35.32 ? 97 ALA V CB 1 ATOM 4600 N N . SER D 2 98 ? 40.584 16.268 31.668 1.00 34.85 ? 98 SER V N 1 ATOM 4601 C CA . SER D 2 98 ? 39.724 17.392 31.891 1.00 35.13 ? 98 SER V CA 1 ATOM 4602 C C . SER D 2 98 ? 38.568 17.045 32.793 1.00 35.59 ? 98 SER V C 1 ATOM 4603 O O . SER D 2 98 ? 37.839 16.102 32.535 1.00 35.75 ? 98 SER V O 1 ATOM 4604 C CB . SER D 2 98 ? 39.208 17.937 30.576 1.00 35.05 ? 98 SER V CB 1 ATOM 4605 O OG . SER D 2 98 ? 38.084 18.774 30.798 1.00 35.60 ? 98 SER V OG 1 ATOM 4606 N N . CYS D 2 99 ? 38.390 17.828 33.851 1.00 36.26 ? 99 CYS V N 1 ATOM 4607 C CA . CYS D 2 99 ? 37.285 17.612 34.776 1.00 36.72 ? 99 CYS V CA 1 ATOM 4608 C C . CYS D 2 99 ? 36.841 18.923 35.372 1.00 35.70 ? 99 CYS V C 1 ATOM 4609 O O . CYS D 2 99 ? 37.494 19.945 35.217 1.00 35.12 ? 99 CYS V O 1 ATOM 4610 C CB . CYS D 2 99 ? 37.696 16.645 35.903 1.00 37.49 ? 99 CYS V CB 1 ATOM 4611 S SG . CYS D 2 99 ? 38.321 17.447 37.446 1.00 41.98 ? 99 CYS V SG 1 ATOM 4612 N N . THR D 2 100 ? 35.740 18.865 36.090 1.00 35.34 ? 100 THR V N 1 ATOM 4613 C CA . THR D 2 100 ? 35.250 20.004 36.805 1.00 35.84 ? 100 THR V CA 1 ATOM 4614 C C . THR D 2 100 ? 34.645 19.540 38.124 1.00 36.13 ? 100 THR V C 1 ATOM 4615 O O . THR D 2 100 ? 33.778 18.681 38.146 1.00 36.54 ? 100 THR V O 1 ATOM 4616 C CB . THR D 2 100 ? 34.264 20.824 35.899 1.00 36.02 ? 100 THR V CB 1 ATOM 4617 O OG1 . THR D 2 100 ? 34.896 22.044 35.516 1.00 37.09 ? 100 THR V OG1 1 ATOM 4618 C CG2 . THR D 2 100 ? 32.946 21.176 36.569 1.00 35.43 ? 100 THR V CG2 1 ATOM 4619 N N . SER D 2 101 ? 35.117 20.085 39.233 1.00 36.23 ? 101 SER V N 1 ATOM 4620 C CA . SER D 2 101 ? 34.420 19.899 40.490 1.00 36.27 ? 101 SER V CA 1 ATOM 4621 C C . SER D 2 101 ? 32.910 20.052 40.344 1.00 36.52 ? 101 SER V C 1 ATOM 4622 O O . SER D 2 101 ? 32.173 19.460 41.097 1.00 36.83 ? 101 SER V O 1 ATOM 4623 C CB . SER D 2 101 ? 34.924 20.903 41.523 1.00 36.29 ? 101 SER V CB 1 ATOM 4624 O OG . SER D 2 101 ? 33.850 21.576 42.170 1.00 36.37 ? 101 SER V OG 1 ATOM 4625 N N . LEU D 2 102 ? 32.448 20.840 39.381 1.00 37.18 ? 102 LEU V N 1 ATOM 4626 C CA . LEU D 2 102 ? 31.056 21.276 39.364 1.00 38.18 ? 102 LEU V CA 1 ATOM 4627 C C . LEU D 2 102 ? 30.058 20.166 39.180 1.00 39.18 ? 102 LEU V C 1 ATOM 4628 O O . LEU D 2 102 ? 28.965 20.212 39.740 1.00 39.31 ? 102 LEU V O 1 ATOM 4629 C CB . LEU D 2 102 ? 30.825 22.339 38.295 1.00 37.97 ? 102 LEU V CB 1 ATOM 4630 C CG . LEU D 2 102 ? 29.377 22.807 38.056 1.00 37.93 ? 102 LEU V CG 1 ATOM 4631 C CD1 . LEU D 2 102 ? 28.533 23.004 39.350 1.00 37.16 ? 102 LEU V CD1 1 ATOM 4632 C CD2 . LEU D 2 102 ? 29.385 24.072 37.207 1.00 37.10 ? 102 LEU V CD2 1 ATOM 4633 N N . ASP D 2 103 ? 30.434 19.187 38.371 1.00 40.80 ? 103 ASP V N 1 ATOM 4634 C CA . ASP D 2 103 ? 29.583 18.042 38.048 1.00 42.24 ? 103 ASP V CA 1 ATOM 4635 C C . ASP D 2 103 ? 29.685 16.915 39.108 1.00 42.86 ? 103 ASP V C 1 ATOM 4636 O O . ASP D 2 103 ? 28.836 16.011 39.147 1.00 43.12 ? 103 ASP V O 1 ATOM 4637 C CB . ASP D 2 103 ? 29.943 17.558 36.632 1.00 42.33 ? 103 ASP V CB 1 ATOM 4638 C CG . ASP D 2 103 ? 30.107 16.036 36.527 1.00 44.13 ? 103 ASP V CG 1 ATOM 4639 O OD1 . ASP D 2 103 ? 30.607 15.377 37.474 1.00 43.37 ? 103 ASP V OD1 1 ATOM 4640 O OD2 . ASP D 2 103 ? 29.752 15.488 35.457 1.00 47.13 ? 103 ASP V OD2 1 ATOM 4641 N N . GLN D 2 104 ? 30.680 17.041 39.999 1.00 43.46 ? 104 GLN V N 1 ATOM 4642 C CA . GLN D 2 104 ? 31.265 15.949 40.809 1.00 43.65 ? 104 GLN V CA 1 ATOM 4643 C C . GLN D 2 104 ? 32.145 15.124 39.864 1.00 44.04 ? 104 GLN V C 1 ATOM 4644 O O . GLN D 2 104 ? 32.202 13.902 39.943 1.00 44.29 ? 104 GLN V O 1 ATOM 4645 C CB . GLN D 2 104 ? 30.204 15.091 41.527 1.00 43.56 ? 104 GLN V CB 1 ATOM 4646 C CG . GLN D 2 104 ? 29.341 15.835 42.558 1.00 43.37 ? 104 GLN V CG 1 ATOM 4647 C CD . GLN D 2 104 ? 28.358 16.824 41.924 1.00 42.42 ? 104 GLN V CD 1 ATOM 4648 O OE1 . GLN D 2 104 ? 28.551 18.040 41.987 1.00 40.90 ? 104 GLN V OE1 1 ATOM 4649 N NE2 . GLN D 2 104 ? 27.315 16.299 41.291 1.00 41.98 ? 104 GLN V NE2 1 ATOM 4650 N N . SER D 2 105 ? 32.844 15.836 38.980 1.00 44.50 ? 105 SER V N 1 ATOM 4651 C CA . SER D 2 105 ? 33.414 15.291 37.744 1.00 44.86 ? 105 SER V CA 1 ATOM 4652 C C . SER D 2 105 ? 34.793 14.671 37.859 1.00 44.95 ? 105 SER V C 1 ATOM 4653 O O . SER D 2 105 ? 35.135 13.812 37.061 1.00 44.59 ? 105 SER V O 1 ATOM 4654 C CB . SER D 2 105 ? 33.400 16.372 36.641 1.00 45.07 ? 105 SER V CB 1 ATOM 4655 O OG . SER D 2 105 ? 34.458 16.238 35.704 1.00 45.74 ? 105 SER V OG 1 ATOM 4656 N N . CYS D 2 106 ? 35.595 15.114 38.820 1.00 45.52 ? 106 CYS V N 1 ATOM 4657 C CA . CYS D 2 106 ? 36.918 14.518 38.981 1.00 46.21 ? 106 CYS V CA 1 ATOM 4658 C C . CYS D 2 106 ? 36.888 13.180 39.678 1.00 46.72 ? 106 CYS V C 1 ATOM 4659 O O . CYS D 2 106 ? 37.036 12.141 39.027 1.00 46.72 ? 106 CYS V O 1 ATOM 4660 C CB . CYS D 2 106 ? 37.893 15.456 39.666 1.00 45.88 ? 106 CYS V CB 1 ATOM 4661 S SG . CYS D 2 106 ? 39.180 15.922 38.502 1.00 46.47 ? 106 CYS V SG 1 ATOM 4662 N N . GLU D 2 107 ? 36.699 13.227 40.997 1.00 47.53 ? 107 GLU V N 1 ATOM 4663 C CA . GLU D 2 107 ? 36.526 12.046 41.866 1.00 48.24 ? 107 GLU V CA 1 ATOM 4664 C C . GLU D 2 107 ? 36.540 10.673 41.139 1.00 48.12 ? 107 GLU V C 1 ATOM 4665 O O . GLU D 2 107 ? 37.475 9.868 41.343 1.00 48.12 ? 107 GLU V O 1 ATOM 4666 C CB . GLU D 2 107 ? 35.279 12.212 42.767 1.00 48.46 ? 107 GLU V CB 1 ATOM 4667 C CG . GLU D 2 107 ? 35.241 13.525 43.578 1.00 50.08 ? 107 GLU V CG 1 ATOM 4668 C CD . GLU D 2 107 ? 34.600 14.691 42.798 1.00 53.21 ? 107 GLU V CD 1 ATOM 4669 O OE1 . GLU D 2 107 ? 33.352 14.797 42.815 1.00 54.78 ? 107 GLU V OE1 1 ATOM 4670 O OE2 . GLU D 2 107 ? 35.332 15.506 42.173 1.00 53.44 ? 107 GLU V OE2 1 ATOM 4671 N N . ARG D 2 108 ? 35.537 10.434 40.281 1.00 47.68 ? 108 ARG V N 1 ATOM 4672 C CA . ARG D 2 108 ? 35.341 9.138 39.594 1.00 47.35 ? 108 ARG V CA 1 ATOM 4673 C C . ARG D 2 108 ? 36.606 8.537 38.969 1.00 46.95 ? 108 ARG V C 1 ATOM 4674 O O . ARG D 2 108 ? 37.071 7.466 39.389 1.00 47.00 ? 108 ARG V O 1 ATOM 4675 C CB . ARG D 2 108 ? 34.247 9.238 38.527 1.00 47.41 ? 108 ARG V CB 1 ATOM 4676 C CG . ARG D 2 108 ? 33.110 10.203 38.840 1.00 47.85 ? 108 ARG V CG 1 ATOM 4677 C CD . ARG D 2 108 ? 32.264 9.724 39.993 1.00 48.71 ? 108 ARG V CD 1 ATOM 4678 N NE . ARG D 2 108 ? 31.217 10.685 40.309 1.00 49.22 ? 108 ARG V NE 1 ATOM 4679 C CZ . ARG D 2 108 ? 30.346 10.551 41.307 1.00 49.90 ? 108 ARG V CZ 1 ATOM 4680 N NH1 . ARG D 2 108 ? 30.380 9.488 42.109 1.00 49.18 ? 108 ARG V NH1 1 ATOM 4681 N NH2 . ARG D 2 108 ? 29.432 11.492 41.504 1.00 50.26 ? 108 ARG V NH2 1 ATOM 4682 N N . GLY D 2 109 ? 37.159 9.229 37.975 1.00 46.32 ? 109 GLY V N 1 ATOM 4683 C CA . GLY D 2 109 ? 38.369 8.764 37.303 1.00 45.69 ? 109 GLY V CA 1 ATOM 4684 C C . GLY D 2 109 ? 38.072 8.083 35.981 1.00 45.14 ? 109 GLY V C 1 ATOM 4685 O O . GLY D 2 109 ? 38.909 7.341 35.449 1.00 45.22 ? 109 GLY V O 1 ATOM 4686 N N . ARG D 2 110 ? 36.859 8.314 35.479 1.00 44.41 ? 110 ARG V N 1 ATOM 4687 C CA . ARG D 2 110 ? 36.496 8.042 34.081 1.00 43.50 ? 110 ARG V CA 1 ATOM 4688 C C . ARG D 2 110 ? 36.439 9.356 33.281 1.00 42.68 ? 110 ARG V C 1 ATOM 4689 O O . ARG D 2 110 ? 35.584 9.501 32.405 1.00 42.43 ? 110 ARG V O 1 ATOM 4690 C CB . ARG D 2 110 ? 35.154 7.275 33.968 1.00 43.67 ? 110 ARG V CB 1 ATOM 4691 C CG . ARG D 2 110 ? 34.046 7.610 35.004 1.00 43.88 ? 110 ARG V CG 1 ATOM 4692 C CD . ARG D 2 110 ? 33.478 9.052 34.912 1.00 44.18 ? 110 ARG V CD 1 ATOM 4693 N NE . ARG D 2 110 ? 34.363 10.039 35.546 1.00 44.17 ? 110 ARG V NE 1 ATOM 4694 C CZ . ARG D 2 110 ? 34.774 11.183 34.997 1.00 43.83 ? 110 ARG V CZ 1 ATOM 4695 N NH1 . ARG D 2 110 ? 34.375 11.547 33.791 1.00 44.46 ? 110 ARG V NH1 1 ATOM 4696 N NH2 . ARG D 2 110 ? 35.594 11.975 35.661 1.00 43.99 ? 110 ARG V NH2 1 ATOM 4697 N N . GLU D 2 111 ? 37.361 10.279 33.610 1.00 41.71 ? 111 GLU V N 1 ATOM 4698 C CA . GLU D 2 111 ? 37.477 11.681 33.119 1.00 40.59 ? 111 GLU V CA 1 ATOM 4699 C C . GLU D 2 111 ? 37.118 12.000 31.670 1.00 39.58 ? 111 GLU V C 1 ATOM 4700 O O . GLU D 2 111 ? 36.415 11.248 31.017 1.00 39.85 ? 111 GLU V O 1 ATOM 4701 C CB . GLU D 2 111 ? 38.876 12.214 33.422 1.00 40.73 ? 111 GLU V CB 1 ATOM 4702 C CG . GLU D 2 111 ? 39.010 12.675 34.849 1.00 42.58 ? 111 GLU V CG 1 ATOM 4703 C CD . GLU D 2 111 ? 40.307 13.416 35.133 1.00 44.47 ? 111 GLU V CD 1 ATOM 4704 O OE1 . GLU D 2 111 ? 40.246 14.658 35.285 1.00 43.71 ? 111 GLU V OE1 1 ATOM 4705 O OE2 . GLU D 2 111 ? 41.374 12.754 35.221 1.00 45.95 ? 111 GLU V OE2 1 ATOM 4706 N N . GLN D 2 112 ? 37.605 13.118 31.155 1.00 38.28 ? 112 GLN V N 1 ATOM 4707 C CA . GLN D 2 112 ? 37.112 13.595 29.872 1.00 37.15 ? 112 GLN V CA 1 ATOM 4708 C C . GLN D 2 112 ? 38.167 14.166 28.939 1.00 36.85 ? 112 GLN V C 1 ATOM 4709 O O . GLN D 2 112 ? 37.817 14.895 28.006 1.00 36.56 ? 112 GLN V O 1 ATOM 4710 C CB . GLN D 2 112 ? 36.002 14.632 30.092 1.00 37.12 ? 112 GLN V CB 1 ATOM 4711 C CG . GLN D 2 112 ? 34.605 14.078 30.335 1.00 35.77 ? 112 GLN V CG 1 ATOM 4712 C CD . GLN D 2 112 ? 33.847 13.853 29.053 1.00 34.14 ? 112 GLN V CD 1 ATOM 4713 O OE1 . GLN D 2 112 ? 34.234 13.032 28.228 1.00 35.04 ? 112 GLN V OE1 1 ATOM 4714 N NE2 . GLN D 2 112 ? 32.761 14.576 28.878 1.00 32.62 ? 112 GLN V NE2 1 ATOM 4715 N N . SER D 2 113 ? 39.437 13.859 29.204 1.00 36.50 ? 113 SER V N 1 ATOM 4716 C CA . SER D 2 113 ? 40.565 14.159 28.301 1.00 36.63 ? 113 SER V CA 1 ATOM 4717 C C . SER D 2 113 ? 40.245 14.851 26.961 1.00 36.83 ? 113 SER V C 1 ATOM 4718 O O . SER D 2 113 ? 39.487 14.309 26.149 1.00 37.02 ? 113 SER V O 1 ATOM 4719 C CB . SER D 2 113 ? 41.291 12.857 27.960 1.00 36.66 ? 113 SER V CB 1 ATOM 4720 O OG . SER D 2 113 ? 40.569 12.109 26.990 1.00 35.77 ? 113 SER V OG 1 ATOM 4721 N N . LEU D 2 114 ? 40.845 16.016 26.706 1.00 36.78 ? 114 LEU V N 1 ATOM 4722 C CA . LEU D 2 114 ? 40.716 16.669 25.388 1.00 36.58 ? 114 LEU V CA 1 ATOM 4723 C C . LEU D 2 114 ? 42.048 17.179 24.840 1.00 36.61 ? 114 LEU V C 1 ATOM 4724 O O . LEU D 2 114 ? 42.990 17.428 25.594 1.00 36.68 ? 114 LEU V O 1 ATOM 4725 C CB . LEU D 2 114 ? 39.667 17.790 25.414 1.00 36.60 ? 114 LEU V CB 1 ATOM 4726 C CG . LEU D 2 114 ? 40.019 19.251 25.735 1.00 36.16 ? 114 LEU V CG 1 ATOM 4727 C CD1 . LEU D 2 114 ? 38.828 20.170 25.427 1.00 35.59 ? 114 LEU V CD1 1 ATOM 4728 C CD2 . LEU D 2 114 ? 40.470 19.427 27.172 1.00 35.62 ? 114 LEU V CD2 1 ATOM 4729 N N . GLN D 2 115 ? 42.118 17.336 23.525 1.00 36.52 ? 115 GLN V N 1 ATOM 4730 C CA . GLN D 2 115 ? 43.335 17.819 22.893 1.00 36.52 ? 115 GLN V CA 1 ATOM 4731 C C . GLN D 2 115 ? 43.425 19.330 22.983 1.00 36.67 ? 115 GLN V C 1 ATOM 4732 O O . GLN D 2 115 ? 42.412 20.016 22.926 1.00 36.48 ? 115 GLN V O 1 ATOM 4733 C CB . GLN D 2 115 ? 43.382 17.367 21.440 1.00 36.48 ? 115 GLN V CB 1 ATOM 4734 C CG . GLN D 2 115 ? 44.492 17.994 20.630 1.00 35.90 ? 115 GLN V CG 1 ATOM 4735 C CD . GLN D 2 115 ? 45.172 16.996 19.736 1.00 34.89 ? 115 GLN V CD 1 ATOM 4736 O OE1 . GLN D 2 115 ? 45.844 16.078 20.211 1.00 34.19 ? 115 GLN V OE1 1 ATOM 4737 N NE2 . GLN D 2 115 ? 45.005 17.163 18.431 1.00 34.38 ? 115 GLN V NE2 1 ATOM 4738 N N . CYS D 2 116 ? 44.642 19.842 23.122 1.00 37.07 ? 116 CYS V N 1 ATOM 4739 C CA . CYS D 2 116 ? 44.859 21.283 23.192 1.00 37.85 ? 116 CYS V CA 1 ATOM 4740 C C . CYS D 2 116 ? 44.776 21.930 21.821 1.00 38.42 ? 116 CYS V C 1 ATOM 4741 O O . CYS D 2 116 ? 45.214 21.323 20.853 1.00 38.99 ? 116 CYS V O 1 ATOM 4742 C CB . CYS D 2 116 ? 46.228 21.566 23.784 1.00 37.50 ? 116 CYS V CB 1 ATOM 4743 S SG . CYS D 2 116 ? 46.279 21.829 25.583 1.00 38.33 ? 116 CYS V SG 1 ATOM 4744 N N . ARG D 2 117 ? 44.217 23.143 21.731 1.00 39.00 ? 117 ARG V N 1 ATOM 4745 C CA . ARG D 2 117 ? 44.217 23.899 20.472 1.00 39.59 ? 117 ARG V CA 1 ATOM 4746 C C . ARG D 2 117 ? 45.652 24.227 20.076 1.00 39.85 ? 117 ARG V C 1 ATOM 4747 O O . ARG D 2 117 ? 46.232 23.542 19.221 1.00 40.32 ? 117 ARG V O 1 ATOM 4748 C CB . ARG D 2 117 ? 43.359 25.181 20.522 1.00 39.57 ? 117 ARG V CB 1 ATOM 4749 C CG . ARG D 2 117 ? 41.846 24.977 20.231 1.00 41.69 ? 117 ARG V CG 1 ATOM 4750 C CD . ARG D 2 117 ? 41.240 25.957 19.137 1.00 43.99 ? 117 ARG V CD 1 ATOM 4751 N NE . ARG D 2 117 ? 41.172 25.379 17.771 1.00 43.70 ? 117 ARG V NE 1 ATOM 4752 C CZ . ARG D 2 117 ? 41.346 26.056 16.628 1.00 42.43 ? 117 ARG V CZ 1 ATOM 4753 N NH1 . ARG D 2 117 ? 41.606 27.361 16.636 1.00 40.89 ? 117 ARG V NH1 1 ATOM 4754 N NH2 . ARG D 2 117 ? 41.270 25.417 15.465 1.00 41.61 ? 117 ARG V NH2 1 ATOM 4755 N N . TYR D 2 118 ? 46.235 25.236 20.723 1.00 39.91 ? 118 TYR V N 1 ATOM 4756 C CA . TYR D 2 118 ? 47.501 25.819 20.272 1.00 40.07 ? 118 TYR V CA 1 ATOM 4757 C C . TYR D 2 118 ? 48.721 25.170 20.884 1.00 39.79 ? 118 TYR V C 1 ATOM 4758 O O . TYR D 2 118 ? 48.862 25.197 22.098 1.00 40.12 ? 118 TYR V O 1 ATOM 4759 C CB . TYR D 2 118 ? 47.518 27.303 20.605 1.00 40.18 ? 118 TYR V CB 1 ATOM 4760 C CG . TYR D 2 118 ? 46.235 27.995 20.230 1.00 41.61 ? 118 TYR V CG 1 ATOM 4761 C CD1 . TYR D 2 118 ? 45.848 28.108 18.891 1.00 42.49 ? 118 TYR V CD1 1 ATOM 4762 C CD2 . TYR D 2 118 ? 45.397 28.533 21.213 1.00 42.92 ? 118 TYR V CD2 1 ATOM 4763 C CE1 . TYR D 2 118 ? 44.665 28.741 18.536 1.00 43.34 ? 118 TYR V CE1 1 ATOM 4764 C CE2 . TYR D 2 118 ? 44.213 29.176 20.873 1.00 43.14 ? 118 TYR V CE2 1 ATOM 4765 C CZ . TYR D 2 118 ? 43.858 29.275 19.532 1.00 44.08 ? 118 TYR V CZ 1 ATOM 4766 O OH . TYR D 2 118 ? 42.694 29.906 19.177 1.00 45.68 ? 118 TYR V OH 1 ATOM 4767 N N . PRO D 2 119 ? 49.606 24.570 20.059 1.00 39.52 ? 119 PRO V N 1 ATOM 4768 C CA . PRO D 2 119 ? 50.898 24.212 20.667 1.00 39.32 ? 119 PRO V CA 1 ATOM 4769 C C . PRO D 2 119 ? 51.578 25.416 21.369 1.00 38.84 ? 119 PRO V C 1 ATOM 4770 O O . PRO D 2 119 ? 52.223 26.233 20.714 1.00 38.53 ? 119 PRO V O 1 ATOM 4771 C CB . PRO D 2 119 ? 51.706 23.656 19.475 1.00 39.28 ? 119 PRO V CB 1 ATOM 4772 C CG . PRO D 2 119 ? 50.640 22.981 18.619 1.00 39.18 ? 119 PRO V CG 1 ATOM 4773 C CD . PRO D 2 119 ? 49.382 23.850 18.781 1.00 39.58 ? 119 PRO V CD 1 ATOM 4774 N N . THR D 2 120 ? 51.403 25.482 22.699 1.00 38.39 ? 120 THR V N 1 ATOM 4775 C CA . THR D 2 120 ? 51.712 26.631 23.596 1.00 37.97 ? 120 THR V CA 1 ATOM 4776 C C . THR D 2 120 ? 50.597 26.739 24.655 1.00 37.53 ? 120 THR V C 1 ATOM 4777 O O . THR D 2 120 ? 50.411 27.756 25.333 1.00 37.23 ? 120 THR V O 1 ATOM 4778 C CB . THR D 2 120 ? 51.847 27.999 22.867 1.00 38.11 ? 120 THR V CB 1 ATOM 4779 O OG1 . THR D 2 120 ? 50.789 28.149 21.901 1.00 38.32 ? 120 THR V OG1 1 ATOM 4780 C CG2 . THR D 2 120 ? 53.246 28.157 22.213 1.00 37.53 ? 120 THR V CG2 1 ATOM 4781 N N . GLU D 2 121 ? 49.837 25.665 24.766 1.00 37.10 ? 121 GLU V N 1 ATOM 4782 C CA . GLU D 2 121 ? 48.744 25.576 25.708 1.00 36.45 ? 121 GLU V CA 1 ATOM 4783 C C . GLU D 2 121 ? 49.083 24.339 26.540 1.00 36.30 ? 121 GLU V C 1 ATOM 4784 O O . GLU D 2 121 ? 49.340 23.258 26.004 1.00 36.29 ? 121 GLU V O 1 ATOM 4785 C CB . GLU D 2 121 ? 47.434 25.406 24.940 1.00 36.21 ? 121 GLU V CB 1 ATOM 4786 C CG . GLU D 2 121 ? 46.162 25.650 25.695 1.00 35.36 ? 121 GLU V CG 1 ATOM 4787 C CD . GLU D 2 121 ? 44.943 25.517 24.804 1.00 34.64 ? 121 GLU V CD 1 ATOM 4788 O OE1 . GLU D 2 121 ? 43.868 26.068 25.124 1.00 34.16 ? 121 GLU V OE1 1 ATOM 4789 O OE2 . GLU D 2 121 ? 45.067 24.858 23.760 1.00 35.40 ? 121 GLU V OE2 1 ATOM 4790 N N . HIS D 2 122 ? 49.138 24.524 27.851 1.00 35.79 ? 122 HIS V N 1 ATOM 4791 C CA . HIS D 2 122 ? 49.545 23.477 28.770 1.00 34.96 ? 122 HIS V CA 1 ATOM 4792 C C . HIS D 2 122 ? 48.347 22.752 29.369 1.00 34.95 ? 122 HIS V C 1 ATOM 4793 O O . HIS D 2 122 ? 47.240 23.313 29.477 1.00 35.39 ? 122 HIS V O 1 ATOM 4794 C CB . HIS D 2 122 ? 50.347 24.097 29.899 1.00 34.61 ? 122 HIS V CB 1 ATOM 4795 C CG . HIS D 2 122 ? 51.488 24.940 29.434 1.00 34.12 ? 122 HIS V CG 1 ATOM 4796 N ND1 . HIS D 2 122 ? 52.178 24.681 28.272 1.00 34.68 ? 122 HIS V ND1 1 ATOM 4797 C CD2 . HIS D 2 122 ? 52.084 26.017 29.993 1.00 33.93 ? 122 HIS V CD2 1 ATOM 4798 C CE1 . HIS D 2 122 ? 53.143 25.574 28.128 1.00 35.21 ? 122 HIS V CE1 1 ATOM 4799 N NE2 . HIS D 2 122 ? 53.105 26.399 29.159 1.00 34.08 ? 122 HIS V NE2 1 ATOM 4800 N N . CYS D 2 123 ? 48.552 21.499 29.756 1.00 34.30 ? 123 CYS V N 1 ATOM 4801 C CA . CYS D 2 123 ? 47.580 20.867 30.614 1.00 33.71 ? 123 CYS V CA 1 ATOM 4802 C C . CYS D 2 123 ? 47.665 21.688 31.872 1.00 33.10 ? 123 CYS V C 1 ATOM 4803 O O . CYS D 2 123 ? 48.754 21.940 32.386 1.00 32.88 ? 123 CYS V O 1 ATOM 4804 C CB . CYS D 2 123 ? 47.931 19.413 30.900 1.00 33.89 ? 123 CYS V CB 1 ATOM 4805 S SG . CYS D 2 123 ? 48.054 18.391 29.452 1.00 34.35 ? 123 CYS V SG 1 ATOM 4806 N N . ILE D 2 124 ? 46.518 22.147 32.341 1.00 32.53 ? 124 ILE V N 1 ATOM 4807 C CA . ILE D 2 124 ? 46.497 22.950 33.539 1.00 31.82 ? 124 ILE V CA 1 ATOM 4808 C C . ILE D 2 124 ? 45.488 22.469 34.558 1.00 31.76 ? 124 ILE V C 1 ATOM 4809 O O . ILE D 2 124 ? 44.452 21.912 34.207 1.00 31.55 ? 124 ILE V O 1 ATOM 4810 C CB . ILE D 2 124 ? 46.214 24.406 33.218 1.00 31.57 ? 124 ILE V CB 1 ATOM 4811 C CG1 . ILE D 2 124 ? 44.861 24.530 32.524 1.00 30.85 ? 124 ILE V CG1 1 ATOM 4812 C CG2 . ILE D 2 124 ? 47.352 24.987 32.393 1.00 30.86 ? 124 ILE V CG2 1 ATOM 4813 C CD1 . ILE D 2 124 ? 43.903 25.466 33.225 1.00 29.61 ? 124 ILE V CD1 1 ATOM 4814 N N . GLU D 2 125 ? 45.817 22.668 35.825 1.00 31.92 ? 125 GLU V N 1 ATOM 4815 C CA . GLU D 2 125 ? 44.832 22.496 36.878 1.00 32.61 ? 125 GLU V CA 1 ATOM 4816 C C . GLU D 2 125 ? 44.716 23.762 37.715 1.00 32.03 ? 125 GLU V C 1 ATOM 4817 O O . GLU D 2 125 ? 45.713 24.421 38.017 1.00 31.97 ? 125 GLU V O 1 ATOM 4818 C CB . GLU D 2 125 ? 45.153 21.287 37.762 1.00 32.98 ? 125 GLU V CB 1 ATOM 4819 C CG . GLU D 2 125 ? 43.941 20.785 38.582 1.00 35.86 ? 125 GLU V CG 1 ATOM 4820 C CD . GLU D 2 125 ? 44.163 19.397 39.235 1.00 40.35 ? 125 GLU V CD 1 ATOM 4821 O OE1 . GLU D 2 125 ? 43.170 18.745 39.685 1.00 41.79 ? 125 GLU V OE1 1 ATOM 4822 O OE2 . GLU D 2 125 ? 45.331 18.943 39.290 1.00 41.65 ? 125 GLU V OE2 1 ATOM 4823 N N . VAL D 2 126 ? 43.487 24.100 38.073 1.00 31.49 ? 126 VAL V N 1 ATOM 4824 C CA . VAL D 2 126 ? 43.232 25.255 38.895 1.00 31.16 ? 126 VAL V CA 1 ATOM 4825 C C . VAL D 2 126 ? 42.254 24.922 39.994 1.00 31.38 ? 126 VAL V C 1 ATOM 4826 O O . VAL D 2 126 ? 41.074 24.638 39.754 1.00 31.50 ? 126 VAL V O 1 ATOM 4827 C CB . VAL D 2 126 ? 42.689 26.441 38.092 1.00 31.01 ? 126 VAL V CB 1 ATOM 4828 C CG1 . VAL D 2 126 ? 43.634 26.791 36.975 1.00 30.89 ? 126 VAL V CG1 1 ATOM 4829 C CG2 . VAL D 2 126 ? 41.304 26.154 37.555 1.00 30.94 ? 126 VAL V CG2 1 ATOM 4830 N N . VAL D 2 127 ? 42.747 24.963 41.217 1.00 31.40 ? 127 VAL V N 1 ATOM 4831 C CA . VAL D 2 127 ? 41.877 24.710 42.333 1.00 31.47 ? 127 VAL V CA 1 ATOM 4832 C C . VAL D 2 127 ? 41.512 26.026 43.025 1.00 31.69 ? 127 VAL V C 1 ATOM 4833 O O . VAL D 2 127 ? 42.276 26.991 42.988 1.00 31.59 ? 127 VAL V O 1 ATOM 4834 C CB . VAL D 2 127 ? 42.487 23.655 43.253 1.00 31.22 ? 127 VAL V CB 1 ATOM 4835 C CG1 . VAL D 2 127 ? 43.826 24.122 43.770 1.00 30.92 ? 127 VAL V CG1 1 ATOM 4836 C CG2 . VAL D 2 127 ? 41.515 23.264 44.371 1.00 31.21 ? 127 VAL V CG2 1 ATOM 4837 N N . THR D 2 128 ? 40.318 26.063 43.607 1.00 32.13 ? 128 THR V N 1 ATOM 4838 C CA . THR D 2 128 ? 39.789 27.257 44.243 1.00 32.62 ? 128 THR V CA 1 ATOM 4839 C C . THR D 2 128 ? 38.901 26.877 45.422 1.00 33.12 ? 128 THR V C 1 ATOM 4840 O O . THR D 2 128 ? 37.695 26.707 45.302 1.00 33.21 ? 128 THR V O 1 ATOM 4841 C CB . THR D 2 128 ? 39.074 28.162 43.197 1.00 32.62 ? 128 THR V CB 1 ATOM 4842 O OG1 . THR D 2 128 ? 40.057 28.953 42.516 1.00 32.28 ? 128 THR V OG1 1 ATOM 4843 C CG2 . THR D 2 128 ? 38.043 29.091 43.839 1.00 32.26 ? 128 THR V CG2 1 ATOM 4844 N N . LEU D 2 129 ? 39.522 26.712 46.568 1.00 34.04 ? 129 LEU V N 1 ATOM 4845 C CA . LEU D 2 129 ? 38.775 26.361 47.743 1.00 35.34 ? 129 LEU V CA 1 ATOM 4846 C C . LEU D 2 129 ? 38.602 27.579 48.629 1.00 36.32 ? 129 LEU V C 1 ATOM 4847 O O . LEU D 2 129 ? 39.546 28.346 48.854 1.00 36.61 ? 129 LEU V O 1 ATOM 4848 C CB . LEU D 2 129 ? 39.493 25.266 48.517 1.00 35.48 ? 129 LEU V CB 1 ATOM 4849 C CG . LEU D 2 129 ? 39.494 23.824 48.012 1.00 35.96 ? 129 LEU V CG 1 ATOM 4850 C CD1 . LEU D 2 129 ? 39.732 22.857 49.196 1.00 36.29 ? 129 LEU V CD1 1 ATOM 4851 C CD2 . LEU D 2 129 ? 38.191 23.489 47.304 1.00 36.94 ? 129 LEU V CD2 1 ATOM 4852 N N . GLN D 2 130 ? 37.394 27.745 49.149 1.00 37.20 ? 130 GLN V N 1 ATOM 4853 C CA . GLN D 2 130 ? 37.101 28.885 49.997 1.00 38.10 ? 130 GLN V CA 1 ATOM 4854 C C . GLN D 2 130 ? 36.449 28.475 51.326 1.00 38.69 ? 130 GLN V C 1 ATOM 4855 O O . GLN D 2 130 ? 36.843 27.468 51.926 1.00 38.65 ? 130 GLN V O 1 ATOM 4856 C CB . GLN D 2 130 ? 36.268 29.910 49.217 1.00 38.05 ? 130 GLN V CB 1 ATOM 4857 C CG . GLN D 2 130 ? 35.326 29.315 48.189 1.00 38.31 ? 130 GLN V CG 1 ATOM 4858 C CD . GLN D 2 130 ? 34.835 30.335 47.155 1.00 39.01 ? 130 GLN V CD 1 ATOM 4859 O OE1 . GLN D 2 130 ? 34.682 31.528 47.452 1.00 38.61 ? 130 GLN V OE1 1 ATOM 4860 N NE2 . GLN D 2 130 ? 34.563 29.854 45.935 1.00 38.32 ? 130 GLN V NE2 1 ATOM 4861 N N . SER D 2 131 ? 35.483 29.270 51.788 1.00 39.33 ? 131 SER V N 1 ATOM 4862 C CA . SER D 2 131 ? 34.675 28.934 52.955 1.00 39.98 ? 131 SER V CA 1 ATOM 4863 C C . SER D 2 131 ? 33.256 29.495 52.840 1.00 40.52 ? 131 SER V C 1 ATOM 4864 O O . SER D 2 131 ? 33.074 30.689 52.599 1.00 40.49 ? 131 SER V O 1 ATOM 4865 C CB . SER D 2 131 ? 35.350 29.400 54.250 1.00 40.00 ? 131 SER V CB 1 ATOM 4866 O OG . SER D 2 131 ? 36.374 28.496 54.637 1.00 39.65 ? 131 SER V OG 1 ATOM 4867 N N . THR D 2 132 ? 32.277 28.600 53.008 1.00 41.24 ? 132 THR V N 1 ATOM 4868 C CA . THR D 2 132 ? 30.820 28.864 52.942 1.00 42.04 ? 132 THR V CA 1 ATOM 4869 C C . THR D 2 132 ? 30.349 30.166 52.303 1.00 42.51 ? 132 THR V C 1 ATOM 4870 O O . THR D 2 132 ? 29.829 30.145 51.180 1.00 43.04 ? 132 THR V O 1 ATOM 4871 C CB . THR D 2 132 ? 30.155 28.686 54.296 1.00 42.01 ? 132 THR V CB 1 ATOM 4872 O OG1 . THR D 2 132 ? 31.177 28.486 55.281 1.00 42.97 ? 132 THR V OG1 1 ATOM 4873 C CG2 . THR D 2 132 ? 29.237 27.465 54.272 1.00 42.58 ? 132 THR V CG2 1 ATOM 4874 N N . GLU D 2 133 ? 30.520 31.288 53.000 1.00 42.75 ? 133 GLU V N 1 ATOM 4875 C CA . GLU D 2 133 ? 30.187 32.599 52.436 1.00 42.94 ? 133 GLU V CA 1 ATOM 4876 C C . GLU D 2 133 ? 30.429 32.639 50.903 1.00 42.93 ? 133 GLU V C 1 ATOM 4877 O O . GLU D 2 133 ? 29.519 32.999 50.143 1.00 43.01 ? 133 GLU V O 1 ATOM 4878 C CB . GLU D 2 133 ? 30.935 33.720 53.182 1.00 43.08 ? 133 GLU V CB 1 ATOM 4879 C CG . GLU D 2 133 ? 30.482 33.937 54.651 1.00 43.81 ? 133 GLU V CG 1 ATOM 4880 C CD . GLU D 2 133 ? 31.355 34.938 55.437 1.00 44.78 ? 133 GLU V CD 1 ATOM 4881 O OE1 . GLU D 2 133 ? 30.981 35.286 56.578 1.00 44.27 ? 133 GLU V OE1 1 ATOM 4882 O OE2 . GLU D 2 133 ? 32.408 35.383 54.925 1.00 45.61 ? 133 GLU V OE2 1 ATOM 4883 N N . ARG D 2 134 ? 31.633 32.235 50.467 1.00 42.77 ? 134 ARG V N 1 ATOM 4884 C CA . ARG D 2 134 ? 31.975 32.066 49.044 1.00 42.49 ? 134 ARG V CA 1 ATOM 4885 C C . ARG D 2 134 ? 31.890 33.366 48.277 1.00 42.00 ? 134 ARG V C 1 ATOM 4886 O O . ARG D 2 134 ? 30.903 33.613 47.573 1.00 42.04 ? 134 ARG V O 1 ATOM 4887 C CB . ARG D 2 134 ? 31.060 31.033 48.368 1.00 42.91 ? 134 ARG V CB 1 ATOM 4888 C CG . ARG D 2 134 ? 31.729 29.752 47.922 1.00 44.07 ? 134 ARG V CG 1 ATOM 4889 C CD . ARG D 2 134 ? 30.743 28.589 47.907 1.00 46.13 ? 134 ARG V CD 1 ATOM 4890 N NE . ARG D 2 134 ? 31.428 27.295 47.847 1.00 47.95 ? 134 ARG V NE 1 ATOM 4891 C CZ . ARG D 2 134 ? 31.976 26.661 48.891 1.00 48.01 ? 134 ARG V CZ 1 ATOM 4892 N NH1 . ARG D 2 134 ? 31.944 27.186 50.112 1.00 47.27 ? 134 ARG V NH1 1 ATOM 4893 N NH2 . ARG D 2 134 ? 32.575 25.491 48.707 1.00 47.94 ? 134 ARG V NH2 1 ATOM 4894 N N . SER D 2 135 ? 32.923 34.192 48.404 1.00 41.40 ? 135 SER V N 1 ATOM 4895 C CA . SER D 2 135 ? 32.929 35.497 47.725 1.00 40.64 ? 135 SER V CA 1 ATOM 4896 C C . SER D 2 135 ? 33.167 35.393 46.208 1.00 39.91 ? 135 SER V C 1 ATOM 4897 O O . SER D 2 135 ? 32.687 36.229 45.451 1.00 39.77 ? 135 SER V O 1 ATOM 4898 C CB . SER D 2 135 ? 33.877 36.502 48.410 1.00 40.62 ? 135 SER V CB 1 ATOM 4899 O OG . SER D 2 135 ? 35.240 36.133 48.278 1.00 40.89 ? 135 SER V OG 1 ATOM 4900 N N . LEU D 2 136 ? 33.884 34.369 45.763 1.00 39.20 ? 136 LEU V N 1 ATOM 4901 C CA . LEU D 2 136 ? 33.934 34.077 44.334 1.00 38.92 ? 136 LEU V CA 1 ATOM 4902 C C . LEU D 2 136 ? 32.879 33.038 43.986 1.00 38.42 ? 136 LEU V C 1 ATOM 4903 O O . LEU D 2 136 ? 32.505 32.221 44.836 1.00 38.86 ? 136 LEU V O 1 ATOM 4904 C CB . LEU D 2 136 ? 35.313 33.584 43.914 1.00 39.23 ? 136 LEU V CB 1 ATOM 4905 C CG . LEU D 2 136 ? 36.538 34.428 44.315 1.00 40.75 ? 136 LEU V CG 1 ATOM 4906 C CD1 . LEU D 2 136 ? 37.794 33.923 43.598 1.00 41.21 ? 136 LEU V CD1 1 ATOM 4907 C CD2 . LEU D 2 136 ? 36.357 35.936 44.066 1.00 42.18 ? 136 LEU V CD2 1 ATOM 4908 N N . LYS D 2 137 ? 32.367 33.087 42.757 1.00 37.41 ? 137 LYS V N 1 ATOM 4909 C CA . LYS D 2 137 ? 31.411 32.089 42.305 1.00 36.34 ? 137 LYS V CA 1 ATOM 4910 C C . LYS D 2 137 ? 32.115 31.123 41.388 1.00 35.85 ? 137 LYS V C 1 ATOM 4911 O O . LYS D 2 137 ? 31.516 30.616 40.456 1.00 36.25 ? 137 LYS V O 1 ATOM 4912 C CB . LYS D 2 137 ? 30.214 32.725 41.594 1.00 36.18 ? 137 LYS V CB 1 ATOM 4913 C CG . LYS D 2 137 ? 29.163 33.407 42.495 1.00 36.45 ? 137 LYS V CG 1 ATOM 4914 C CD . LYS D 2 137 ? 28.520 32.497 43.557 1.00 36.44 ? 137 LYS V CD 1 ATOM 4915 C CE . LYS D 2 137 ? 29.337 32.514 44.863 1.00 36.14 ? 137 LYS V CE 1 ATOM 4916 N NZ . LYS D 2 137 ? 28.543 32.179 46.072 1.00 36.13 ? 137 LYS V NZ 1 ATOM 4917 N N . ASP D 2 138 ? 33.397 30.886 41.648 1.00 35.02 ? 138 ASP V N 1 ATOM 4918 C CA . ASP D 2 138 ? 34.173 29.906 40.905 1.00 34.37 ? 138 ASP V CA 1 ATOM 4919 C C . ASP D 2 138 ? 33.861 28.488 41.354 1.00 33.80 ? 138 ASP V C 1 ATOM 4920 O O . ASP D 2 138 ? 32.916 28.252 42.097 1.00 33.08 ? 138 ASP V O 1 ATOM 4921 C CB . ASP D 2 138 ? 35.667 30.163 41.080 1.00 34.77 ? 138 ASP V CB 1 ATOM 4922 C CG . ASP D 2 138 ? 36.257 31.067 39.996 1.00 35.87 ? 138 ASP V CG 1 ATOM 4923 O OD1 . ASP D 2 138 ? 37.217 30.614 39.296 1.00 35.26 ? 138 ASP V OD1 1 ATOM 4924 O OD2 . ASP D 2 138 ? 35.775 32.228 39.866 1.00 37.50 ? 138 ASP V OD2 1 ATOM 4925 N N . GLU D 2 139 ? 34.677 27.546 40.895 1.00 33.89 ? 139 GLU V N 1 ATOM 4926 C CA . GLU D 2 139 ? 34.476 26.126 41.183 1.00 34.44 ? 139 GLU V CA 1 ATOM 4927 C C . GLU D 2 139 ? 35.697 25.511 41.808 1.00 33.82 ? 139 GLU V C 1 ATOM 4928 O O . GLU D 2 139 ? 36.820 25.849 41.450 1.00 33.91 ? 139 GLU V O 1 ATOM 4929 C CB . GLU D 2 139 ? 34.150 25.365 39.907 1.00 34.86 ? 139 GLU V CB 1 ATOM 4930 C CG . GLU D 2 139 ? 35.044 25.750 38.756 1.00 37.29 ? 139 GLU V CG 1 ATOM 4931 C CD . GLU D 2 139 ? 34.454 25.355 37.421 1.00 40.88 ? 139 GLU V CD 1 ATOM 4932 O OE1 . GLU D 2 139 ? 34.724 26.075 36.419 1.00 40.84 ? 139 GLU V OE1 1 ATOM 4933 O OE2 . GLU D 2 139 ? 33.721 24.326 37.390 1.00 41.98 ? 139 GLU V OE2 1 ATOM 4934 N N . ASP D 2 140 ? 35.469 24.587 42.722 1.00 33.25 ? 140 ASP V N 1 ATOM 4935 C CA . ASP D 2 140 ? 36.544 24.047 43.507 1.00 33.40 ? 140 ASP V CA 1 ATOM 4936 C C . ASP D 2 140 ? 37.714 23.566 42.658 1.00 33.26 ? 140 ASP V C 1 ATOM 4937 O O . ASP D 2 140 ? 38.829 24.053 42.815 1.00 33.27 ? 140 ASP V O 1 ATOM 4938 C CB . ASP D 2 140 ? 36.028 22.917 44.386 1.00 33.89 ? 140 ASP V CB 1 ATOM 4939 C CG . ASP D 2 140 ? 35.177 23.410 45.549 1.00 35.11 ? 140 ASP V CG 1 ATOM 4940 O OD1 . ASP D 2 140 ? 34.585 22.535 46.224 1.00 36.06 ? 140 ASP V OD1 1 ATOM 4941 O OD2 . ASP D 2 140 ? 35.107 24.644 45.798 1.00 35.89 ? 140 ASP V OD2 1 ATOM 4942 N N . TYR D 2 141 ? 37.454 22.624 41.753 1.00 33.03 ? 141 TYR V N 1 ATOM 4943 C CA . TYR D 2 141 ? 38.507 21.988 40.955 1.00 32.58 ? 141 TYR V CA 1 ATOM 4944 C C . TYR D 2 141 ? 38.127 22.007 39.485 1.00 31.91 ? 141 TYR V C 1 ATOM 4945 O O . TYR D 2 141 ? 36.960 21.823 39.139 1.00 31.64 ? 141 TYR V O 1 ATOM 4946 C CB . TYR D 2 141 ? 38.658 20.528 41.356 1.00 33.27 ? 141 TYR V CB 1 ATOM 4947 C CG . TYR D 2 141 ? 39.105 20.239 42.774 1.00 34.23 ? 141 TYR V CG 1 ATOM 4948 C CD1 . TYR D 2 141 ? 38.281 20.522 43.865 1.00 35.38 ? 141 TYR V CD1 1 ATOM 4949 C CD2 . TYR D 2 141 ? 40.324 19.609 43.016 1.00 35.14 ? 141 TYR V CD2 1 ATOM 4950 C CE1 . TYR D 2 141 ? 38.686 20.244 45.169 1.00 35.81 ? 141 TYR V CE1 1 ATOM 4951 C CE2 . TYR D 2 141 ? 40.738 19.320 44.320 1.00 36.04 ? 141 TYR V CE2 1 ATOM 4952 C CZ . TYR D 2 141 ? 39.915 19.643 45.387 1.00 35.77 ? 141 TYR V CZ 1 ATOM 4953 O OH . TYR D 2 141 ? 40.323 19.359 46.666 1.00 35.65 ? 141 TYR V OH 1 ATOM 4954 N N . THR D 2 142 ? 39.123 22.210 38.625 1.00 31.18 ? 142 THR V N 1 ATOM 4955 C CA . THR D 2 142 ? 38.907 22.373 37.178 1.00 30.50 ? 142 THR V CA 1 ATOM 4956 C C . THR D 2 142 ? 40.177 22.049 36.429 1.00 30.03 ? 142 THR V C 1 ATOM 4957 O O . THR D 2 142 ? 41.182 22.733 36.595 1.00 30.02 ? 142 THR V O 1 ATOM 4958 C CB . THR D 2 142 ? 38.515 23.836 36.804 1.00 30.39 ? 142 THR V CB 1 ATOM 4959 O OG1 . THR D 2 142 ? 37.219 24.147 37.320 1.00 30.32 ? 142 THR V OG1 1 ATOM 4960 C CG2 . THR D 2 142 ? 38.489 24.035 35.297 1.00 30.40 ? 142 THR V CG2 1 ATOM 4961 N N . ARG D 2 143 ? 40.147 21.004 35.608 1.00 29.61 ? 143 ARG V N 1 ATOM 4962 C CA . ARG D 2 143 ? 41.324 20.682 34.792 1.00 29.25 ? 143 ARG V CA 1 ATOM 4963 C C . ARG D 2 143 ? 40.980 20.643 33.325 1.00 28.92 ? 143 ARG V C 1 ATOM 4964 O O . ARG D 2 143 ? 39.853 20.319 32.963 1.00 28.82 ? 143 ARG V O 1 ATOM 4965 C CB . ARG D 2 143 ? 42.043 19.411 35.249 1.00 29.12 ? 143 ARG V CB 1 ATOM 4966 C CG . ARG D 2 143 ? 41.152 18.393 35.900 1.00 28.99 ? 143 ARG V CG 1 ATOM 4967 C CD . ARG D 2 143 ? 41.916 17.128 36.237 1.00 29.15 ? 143 ARG V CD 1 ATOM 4968 N NE . ARG D 2 143 ? 42.767 17.232 37.420 1.00 27.62 ? 143 ARG V NE 1 ATOM 4969 C CZ . ARG D 2 143 ? 43.337 16.191 38.018 1.00 27.65 ? 143 ARG V CZ 1 ATOM 4970 N NH1 . ARG D 2 143 ? 43.144 14.960 37.551 1.00 28.72 ? 143 ARG V NH1 1 ATOM 4971 N NH2 . ARG D 2 143 ? 44.096 16.372 39.085 1.00 27.09 ? 143 ARG V NH2 1 ATOM 4972 N N . GLY D 2 144 ? 41.956 21.002 32.497 1.00 28.66 ? 144 GLY V N 1 ATOM 4973 C CA . GLY D 2 144 ? 41.738 21.191 31.076 1.00 28.69 ? 144 GLY V CA 1 ATOM 4974 C C . GLY D 2 144 ? 42.971 21.778 30.435 1.00 28.97 ? 144 GLY V C 1 ATOM 4975 O O . GLY D 2 144 ? 44.037 21.822 31.049 1.00 29.01 ? 144 GLY V O 1 ATOM 4976 N N . CYS D 2 145 ? 42.826 22.213 29.187 1.00 29.23 ? 145 CYS V N 1 ATOM 4977 C CA . CYS D 2 145 ? 43.905 22.853 28.455 1.00 29.56 ? 145 CYS V CA 1 ATOM 4978 C C . CYS D 2 145 ? 43.852 24.312 28.758 1.00 29.06 ? 145 CYS V C 1 ATOM 4979 O O . CYS D 2 145 ? 42.764 24.866 28.879 1.00 29.24 ? 145 CYS V O 1 ATOM 4980 C CB . CYS D 2 145 ? 43.710 22.663 26.965 1.00 29.81 ? 145 CYS V CB 1 ATOM 4981 S SG . CYS D 2 145 ? 44.500 21.164 26.346 1.00 33.60 ? 145 CYS V SG 1 ATOM 4982 N N . GLY D 2 146 ? 45.010 24.948 28.881 1.00 28.64 ? 146 GLY V N 1 ATOM 4983 C CA . GLY D 2 146 ? 45.042 26.393 29.099 1.00 28.54 ? 146 GLY V CA 1 ATOM 4984 C C . GLY D 2 146 ? 46.357 27.043 28.723 1.00 28.80 ? 146 GLY V C 1 ATOM 4985 O O . GLY D 2 146 ? 47.288 26.365 28.286 1.00 28.88 ? 146 GLY V O 1 ATOM 4986 N N . SER D 2 147 ? 46.420 28.366 28.864 1.00 28.99 ? 147 SER V N 1 ATOM 4987 C CA . SER D 2 147 ? 47.679 29.118 28.824 1.00 29.13 ? 147 SER V CA 1 ATOM 4988 C C . SER D 2 147 ? 47.449 30.331 29.661 1.00 29.11 ? 147 SER V C 1 ATOM 4989 O O . SER D 2 147 ? 46.656 31.190 29.302 1.00 28.77 ? 147 SER V O 1 ATOM 4990 C CB . SER D 2 147 ? 48.067 29.548 27.406 1.00 29.52 ? 147 SER V CB 1 ATOM 4991 O OG . SER D 2 147 ? 49.070 30.553 27.445 1.00 28.93 ? 147 SER V OG 1 ATOM 4992 N N . LEU D 2 148 ? 48.138 30.388 30.787 1.00 29.58 ? 148 LEU V N 1 ATOM 4993 C CA . LEU D 2 148 ? 47.900 31.425 31.768 1.00 30.01 ? 148 LEU V CA 1 ATOM 4994 C C . LEU D 2 148 ? 49.215 31.893 32.347 1.00 30.69 ? 148 LEU V C 1 ATOM 4995 O O . LEU D 2 148 ? 50.275 31.480 31.887 1.00 30.38 ? 148 LEU V O 1 ATOM 4996 C CB . LEU D 2 148 ? 46.988 30.902 32.884 1.00 29.79 ? 148 LEU V CB 1 ATOM 4997 C CG . LEU D 2 148 ? 45.648 30.278 32.531 1.00 28.28 ? 148 LEU V CG 1 ATOM 4998 C CD1 . LEU D 2 148 ? 45.031 29.756 33.757 1.00 27.82 ? 148 LEU V CD1 1 ATOM 4999 C CD2 . LEU D 2 148 ? 44.768 31.303 31.961 1.00 28.46 ? 148 LEU V CD2 1 ATOM 5000 N N . PRO D 2 149 ? 49.143 32.763 33.362 1.00 31.69 ? 149 PRO V N 1 ATOM 5001 C CA . PRO D 2 149 ? 50.287 33.386 33.994 1.00 32.83 ? 149 PRO V CA 1 ATOM 5002 C C . PRO D 2 149 ? 51.358 32.426 34.504 1.00 34.11 ? 149 PRO V C 1 ATOM 5003 O O . PRO D 2 149 ? 51.036 31.417 35.149 1.00 34.21 ? 149 PRO V O 1 ATOM 5004 C CB . PRO D 2 149 ? 49.654 34.134 35.158 1.00 32.55 ? 149 PRO V CB 1 ATOM 5005 C CG . PRO D 2 149 ? 48.370 34.549 34.634 1.00 31.99 ? 149 PRO V CG 1 ATOM 5006 C CD . PRO D 2 149 ? 47.892 33.380 33.828 1.00 31.73 ? 149 PRO V CD 1 ATOM 5007 N N . GLY D 2 150 ? 52.616 32.769 34.193 1.00 35.34 ? 150 GLY V N 1 ATOM 5008 C CA . GLY D 2 150 ? 53.812 32.050 34.636 1.00 36.95 ? 150 GLY V CA 1 ATOM 5009 C C . GLY D 2 150 ? 53.725 30.577 34.305 1.00 38.13 ? 150 GLY V C 1 ATOM 5010 O O . GLY D 2 150 ? 54.023 29.716 35.148 1.00 38.06 ? 150 GLY V O 1 ATOM 5011 N N . CYS D 2 151 ? 53.332 30.297 33.062 1.00 39.03 ? 151 CYS V N 1 ATOM 5012 C CA . CYS D 2 151 ? 52.847 28.980 32.712 1.00 39.92 ? 151 CYS V CA 1 ATOM 5013 C C . CYS D 2 151 ? 53.866 27.817 32.804 1.00 40.22 ? 151 CYS V C 1 ATOM 5014 O O . CYS D 2 151 ? 53.644 26.878 33.578 1.00 40.58 ? 151 CYS V O 1 ATOM 5015 C CB . CYS D 2 151 ? 52.125 29.016 31.389 1.00 39.64 ? 151 CYS V CB 1 ATOM 5016 S SG . CYS D 2 151 ? 50.585 28.043 31.375 1.00 42.83 ? 151 CYS V SG 1 ATOM 5017 N N . PRO D 2 152 ? 54.984 27.855 32.048 1.00 40.21 ? 152 PRO V N 1 ATOM 5018 C CA . PRO D 2 152 ? 55.847 26.707 32.341 1.00 39.90 ? 152 PRO V CA 1 ATOM 5019 C C . PRO D 2 152 ? 56.236 26.779 33.821 1.00 39.74 ? 152 PRO V C 1 ATOM 5020 O O . PRO D 2 152 ? 57.158 27.518 34.183 1.00 40.26 ? 152 PRO V O 1 ATOM 5021 C CB . PRO D 2 152 ? 57.056 26.922 31.420 1.00 40.04 ? 152 PRO V CB 1 ATOM 5022 C CG . PRO D 2 152 ? 56.573 27.869 30.347 1.00 40.25 ? 152 PRO V CG 1 ATOM 5023 C CD . PRO D 2 152 ? 55.554 28.747 31.022 1.00 40.15 ? 152 PRO V CD 1 ATOM 5024 N N . GLY D 2 153 ? 55.505 26.051 34.668 1.00 39.10 ? 153 GLY V N 1 ATOM 5025 C CA . GLY D 2 153 ? 55.665 26.136 36.128 1.00 38.49 ? 153 GLY V CA 1 ATOM 5026 C C . GLY D 2 153 ? 54.329 26.190 36.846 1.00 38.02 ? 153 GLY V C 1 ATOM 5027 O O . GLY D 2 153 ? 53.291 25.961 36.227 1.00 38.18 ? 153 GLY V O 1 ATOM 5028 N N . THR D 2 154 ? 54.337 26.472 38.153 1.00 37.41 ? 154 THR V N 1 ATOM 5029 C CA . THR D 2 154 ? 53.073 26.630 38.912 1.00 36.90 ? 154 THR V CA 1 ATOM 5030 C C . THR D 2 154 ? 53.174 27.702 40.004 1.00 35.92 ? 154 THR V C 1 ATOM 5031 O O . THR D 2 154 ? 54.256 28.244 40.231 1.00 35.73 ? 154 THR V O 1 ATOM 5032 C CB . THR D 2 154 ? 52.590 25.311 39.571 1.00 37.23 ? 154 THR V CB 1 ATOM 5033 O OG1 . THR D 2 154 ? 53.145 25.201 40.888 1.00 37.83 ? 154 THR V OG1 1 ATOM 5034 C CG2 . THR D 2 154 ? 52.957 24.068 38.732 1.00 37.78 ? 154 THR V CG2 1 ATOM 5035 N N . ALA D 2 155 ? 52.046 27.994 40.667 1.00 34.93 ? 155 ALA V N 1 ATOM 5036 C CA . ALA D 2 155 ? 51.969 29.008 41.751 1.00 33.85 ? 155 ALA V CA 1 ATOM 5037 C C . ALA D 2 155 ? 50.623 29.046 42.503 1.00 32.85 ? 155 ALA V C 1 ATOM 5038 O O . ALA D 2 155 ? 49.564 28.877 41.905 1.00 32.88 ? 155 ALA V O 1 ATOM 5039 C CB . ALA D 2 155 ? 52.304 30.402 41.225 1.00 33.94 ? 155 ALA V CB 1 ATOM 5040 N N . GLY D 2 156 ? 50.675 29.301 43.809 1.00 31.35 ? 156 GLY V N 1 ATOM 5041 C CA . GLY D 2 156 ? 49.488 29.226 44.642 1.00 29.68 ? 156 GLY V CA 1 ATOM 5042 C C . GLY D 2 156 ? 49.583 29.981 45.947 1.00 28.69 ? 156 GLY V C 1 ATOM 5043 O O . GLY D 2 156 ? 50.658 30.435 46.338 1.00 28.67 ? 156 GLY V O 1 ATOM 5044 N N . PHE D 2 157 ? 48.442 30.085 46.623 1.00 27.71 ? 157 PHE V N 1 ATOM 5045 C CA . PHE D 2 157 ? 48.287 30.907 47.808 1.00 27.18 ? 157 PHE V CA 1 ATOM 5046 C C . PHE D 2 157 ? 47.306 30.241 48.759 1.00 27.50 ? 157 PHE V C 1 ATOM 5047 O O . PHE D 2 157 ? 46.296 29.684 48.301 1.00 27.62 ? 157 PHE V O 1 ATOM 5048 C CB . PHE D 2 157 ? 47.756 32.290 47.400 1.00 26.61 ? 157 PHE V CB 1 ATOM 5049 C CG . PHE D 2 157 ? 47.210 33.115 48.549 1.00 25.54 ? 157 PHE V CG 1 ATOM 5050 C CD1 . PHE D 2 157 ? 48.072 33.799 49.413 1.00 24.63 ? 157 PHE V CD1 1 ATOM 5051 C CD2 . PHE D 2 157 ? 45.839 33.213 48.767 1.00 24.14 ? 157 PHE V CD2 1 ATOM 5052 C CE1 . PHE D 2 157 ? 47.576 34.554 50.479 1.00 22.91 ? 157 PHE V CE1 1 ATOM 5053 C CE2 . PHE D 2 157 ? 45.338 33.969 49.839 1.00 23.82 ? 157 PHE V CE2 1 ATOM 5054 C CZ . PHE D 2 157 ? 46.210 34.637 50.692 1.00 22.51 ? 157 PHE V CZ 1 ATOM 5055 N N . HIS D 2 158 ? 47.578 30.302 50.070 1.00 27.53 ? 158 HIS V N 1 ATOM 5056 C CA . HIS D 2 158 ? 46.545 29.947 51.047 1.00 27.74 ? 158 HIS V CA 1 ATOM 5057 C C . HIS D 2 158 ? 46.514 30.741 52.330 1.00 27.86 ? 158 HIS V C 1 ATOM 5058 O O . HIS D 2 158 ? 47.529 31.221 52.812 1.00 27.73 ? 158 HIS V O 1 ATOM 5059 C CB . HIS D 2 158 ? 46.578 28.454 51.363 1.00 28.11 ? 158 HIS V CB 1 ATOM 5060 C CG . HIS D 2 158 ? 47.412 28.091 52.551 1.00 28.45 ? 158 HIS V CG 1 ATOM 5061 N ND1 . HIS D 2 158 ? 48.789 28.105 52.527 1.00 29.44 ? 158 HIS V ND1 1 ATOM 5062 C CD2 . HIS D 2 158 ? 47.061 27.678 53.793 1.00 28.41 ? 158 HIS V CD2 1 ATOM 5063 C CE1 . HIS D 2 158 ? 49.252 27.735 53.708 1.00 29.18 ? 158 HIS V CE1 1 ATOM 5064 N NE2 . HIS D 2 158 ? 48.223 27.468 54.493 1.00 29.05 ? 158 HIS V NE2 1 ATOM 5065 N N . SER D 2 159 ? 45.309 30.718 52.707 1.00 29.63 ? 159 SER V N 1 ATOM 5066 C CA . SER D 2 159 ? 44.982 31.321 53.955 1.00 30.73 ? 159 SER V CA 1 ATOM 5067 C C . SER D 2 159 ? 44.247 30.262 54.769 1.00 31.37 ? 159 SER V C 1 ATOM 5068 O O . SER D 2 159 ? 43.946 29.200 54.253 1.00 31.86 ? 159 SER V O 1 ATOM 5069 C CB . SER D 2 159 ? 44.064 32.482 53.670 1.00 30.72 ? 159 SER V CB 1 ATOM 5070 O OG . SER D 2 159 ? 43.300 32.770 54.816 1.00 32.88 ? 159 SER V OG 1 ATOM 5071 N N . ASN D 2 160 ? 43.941 30.542 56.031 1.00 32.26 ? 160 ASN V N 1 ATOM 5072 C CA . ASN D 2 160 ? 43.104 29.638 56.824 1.00 33.47 ? 160 ASN V CA 1 ATOM 5073 C C . ASN D 2 160 ? 41.761 29.413 56.108 1.00 32.77 ? 160 ASN V C 1 ATOM 5074 O O . ASN D 2 160 ? 41.246 28.297 56.054 1.00 32.71 ? 160 ASN V O 1 ATOM 5075 C CB . ASN D 2 160 ? 42.918 30.177 58.269 1.00 34.57 ? 160 ASN V CB 1 ATOM 5076 C CG . ASN D 2 160 ? 42.280 29.152 59.227 1.00 39.25 ? 160 ASN V CG 1 ATOM 5077 O OD1 . ASN D 2 160 ? 42.707 27.978 59.277 1.00 40.47 ? 160 ASN V OD1 1 ATOM 5078 N ND2 . ASN D 2 160 ? 41.256 29.616 60.004 1.00 47.99 ? 160 ASN V ND2 1 ATOM 5079 N N . GLN D 2 161 ? 41.220 30.473 55.517 1.00 32.29 ? 161 GLN V N 1 ATOM 5080 C CA . GLN D 2 161 ? 39.921 30.392 54.846 1.00 31.85 ? 161 GLN V CA 1 ATOM 5081 C C . GLN D 2 161 ? 40.004 30.003 53.371 1.00 31.05 ? 161 GLN V C 1 ATOM 5082 O O . GLN D 2 161 ? 39.202 29.188 52.893 1.00 31.04 ? 161 GLN V O 1 ATOM 5083 C CB . GLN D 2 161 ? 39.139 31.705 55.000 1.00 32.10 ? 161 GLN V CB 1 ATOM 5084 C CG . GLN D 2 161 ? 39.012 32.203 56.443 1.00 33.43 ? 161 GLN V CG 1 ATOM 5085 C CD . GLN D 2 161 ? 38.162 31.308 57.372 1.00 35.17 ? 161 GLN V CD 1 ATOM 5086 O OE1 . GLN D 2 161 ? 37.659 31.791 58.388 1.00 35.96 ? 161 GLN V OE1 1 ATOM 5087 N NE2 . GLN D 2 161 ? 38.008 30.018 57.036 1.00 35.33 ? 161 GLN V NE2 1 ATOM 5088 N N . THR D 2 162 ? 41.031 30.702 52.720 1.00 24.28 ? 162 THR V N 1 ATOM 5089 C CA . THR D 2 162 ? 41.026 30.417 51.291 1.00 23.73 ? 162 THR V CA 1 ATOM 5090 C C . THR D 2 162 ? 42.229 29.598 50.793 1.00 23.41 ? 162 THR V C 1 ATOM 5091 O O . THR D 2 162 ? 43.272 29.495 51.450 1.00 22.93 ? 162 THR V O 1 ATOM 5092 C CB . THR D 2 162 ? 40.852 31.729 50.410 1.00 23.95 ? 162 THR V CB 1 ATOM 5093 O OG1 . THR D 2 162 ? 42.122 32.218 49.945 1.00 23.44 ? 162 THR V OG1 1 ATOM 5094 C CG2 . THR D 2 162 ? 40.082 32.844 51.152 1.00 23.54 ? 162 THR V CG2 1 ATOM 5095 N N . PHE D 2 163 ? 42.057 29.034 49.602 1.00 23.16 ? 163 PHE V N 1 ATOM 5096 C CA . PHE D 2 163 ? 43.142 28.401 48.870 1.00 22.80 ? 163 PHE V CA 1 ATOM 5097 C C . PHE D 2 163 ? 43.006 28.620 47.353 1.00 23.04 ? 163 PHE V C 1 ATOM 5098 O O . PHE D 2 163 ? 41.892 28.666 46.805 1.00 22.68 ? 163 PHE V O 1 ATOM 5099 C CB . PHE D 2 163 ? 43.188 26.913 49.206 1.00 22.57 ? 163 PHE V CB 1 ATOM 5100 C CG . PHE D 2 163 ? 44.287 26.162 48.522 1.00 20.74 ? 163 PHE V CG 1 ATOM 5101 C CD1 . PHE D 2 163 ? 45.588 26.651 48.513 1.00 18.94 ? 163 PHE V CD1 1 ATOM 5102 C CD2 . PHE D 2 163 ? 44.022 24.950 47.903 1.00 19.63 ? 163 PHE V CD2 1 ATOM 5103 C CE1 . PHE D 2 163 ? 46.623 25.952 47.884 1.00 18.36 ? 163 PHE V CE1 1 ATOM 5104 C CE2 . PHE D 2 163 ? 45.041 24.237 47.276 1.00 19.80 ? 163 PHE V CE2 1 ATOM 5105 C CZ . PHE D 2 163 ? 46.357 24.744 47.269 1.00 19.13 ? 163 PHE V CZ 1 ATOM 5106 N N . HIS D 2 164 ? 44.162 28.779 46.705 1.00 23.19 ? 164 HIS V N 1 ATOM 5107 C CA . HIS D 2 164 ? 44.272 28.911 45.262 1.00 23.51 ? 164 HIS V CA 1 ATOM 5108 C C . HIS D 2 164 ? 45.519 28.225 44.806 1.00 23.54 ? 164 HIS V C 1 ATOM 5109 O O . HIS D 2 164 ? 46.571 28.406 45.393 1.00 23.33 ? 164 HIS V O 1 ATOM 5110 C CB . HIS D 2 164 ? 44.359 30.376 44.858 1.00 23.70 ? 164 HIS V CB 1 ATOM 5111 C CG . HIS D 2 164 ? 43.147 31.168 45.223 1.00 25.07 ? 164 HIS V CG 1 ATOM 5112 N ND1 . HIS D 2 164 ? 42.014 31.197 44.438 1.00 26.30 ? 164 HIS V ND1 1 ATOM 5113 C CD2 . HIS D 2 164 ? 42.878 31.939 46.301 1.00 26.32 ? 164 HIS V CD2 1 ATOM 5114 C CE1 . HIS D 2 164 ? 41.107 31.967 45.009 1.00 26.77 ? 164 HIS V CE1 1 ATOM 5115 N NE2 . HIS D 2 164 ? 41.603 32.424 46.145 1.00 26.87 ? 164 HIS V NE2 1 ATOM 5116 N N . PHE D 2 165 ? 45.399 27.436 43.753 1.00 24.47 ? 165 PHE V N 1 ATOM 5117 C CA . PHE D 2 165 ? 46.550 26.789 43.148 1.00 25.78 ? 165 PHE V CA 1 ATOM 5118 C C . PHE D 2 165 ? 46.362 26.598 41.644 1.00 26.51 ? 165 PHE V C 1 ATOM 5119 O O . PHE D 2 165 ? 45.255 26.342 41.164 1.00 26.52 ? 165 PHE V O 1 ATOM 5120 C CB . PHE D 2 165 ? 46.788 25.449 43.815 1.00 26.05 ? 165 PHE V CB 1 ATOM 5121 C CG . PHE D 2 165 ? 48.033 24.755 43.377 1.00 27.05 ? 165 PHE V CG 1 ATOM 5122 C CD1 . PHE D 2 165 ? 47.983 23.784 42.384 1.00 28.19 ? 165 PHE V CD1 1 ATOM 5123 C CD2 . PHE D 2 165 ? 49.250 25.036 43.987 1.00 27.84 ? 165 PHE V CD2 1 ATOM 5124 C CE1 . PHE D 2 165 ? 49.141 23.125 41.984 1.00 30.29 ? 165 PHE V CE1 1 ATOM 5125 C CE2 . PHE D 2 165 ? 50.419 24.383 43.607 1.00 28.53 ? 165 PHE V CE2 1 ATOM 5126 C CZ . PHE D 2 165 ? 50.375 23.426 42.610 1.00 29.80 ? 165 PHE V CZ 1 ATOM 5127 N N . LEU D 2 166 ? 47.463 26.729 40.915 1.00 27.33 ? 166 LEU V N 1 ATOM 5128 C CA . LEU D 2 166 ? 47.469 26.561 39.483 1.00 28.15 ? 166 LEU V CA 1 ATOM 5129 C C . LEU D 2 166 ? 48.683 25.744 39.096 1.00 29.16 ? 166 LEU V C 1 ATOM 5130 O O . LEU D 2 166 ? 49.793 25.972 39.594 1.00 28.71 ? 166 LEU V O 1 ATOM 5131 C CB . LEU D 2 166 ? 47.529 27.916 38.792 1.00 28.03 ? 166 LEU V CB 1 ATOM 5132 C CG . LEU D 2 166 ? 47.760 27.912 37.277 1.00 27.77 ? 166 LEU V CG 1 ATOM 5133 C CD1 . LEU D 2 166 ? 46.576 28.517 36.594 1.00 27.38 ? 166 LEU V CD1 1 ATOM 5134 C CD2 . LEU D 2 166 ? 49.026 28.673 36.884 1.00 27.97 ? 166 LEU V CD2 1 ATOM 5135 N N . LYS D 2 167 ? 48.451 24.803 38.184 1.00 30.73 ? 167 LYS V N 1 ATOM 5136 C CA . LYS D 2 167 ? 49.498 23.948 37.639 1.00 32.34 ? 167 LYS V CA 1 ATOM 5137 C C . LYS D 2 167 ? 49.425 23.898 36.098 1.00 33.40 ? 167 LYS V C 1 ATOM 5138 O O . LYS D 2 167 ? 48.400 23.479 35.551 1.00 33.15 ? 167 LYS V O 1 ATOM 5139 C CB . LYS D 2 167 ? 49.348 22.560 38.258 1.00 32.17 ? 167 LYS V CB 1 ATOM 5140 C CG . LYS D 2 167 ? 50.376 21.527 37.860 1.00 32.26 ? 167 LYS V CG 1 ATOM 5141 C CD . LYS D 2 167 ? 50.142 20.295 38.706 1.00 32.12 ? 167 LYS V CD 1 ATOM 5142 C CE . LYS D 2 167 ? 50.596 19.029 38.031 1.00 31.86 ? 167 LYS V CE 1 ATOM 5143 N NZ . LYS D 2 167 ? 49.864 17.888 38.655 1.00 32.56 ? 167 LYS V NZ 1 ATOM 5144 N N . CYS D 2 168 ? 50.489 24.371 35.425 1.00 34.89 ? 168 CYS V N 1 ATOM 5145 C CA . CYS D 2 168 ? 50.664 24.243 33.957 1.00 36.76 ? 168 CYS V CA 1 ATOM 5146 C C . CYS D 2 168 ? 51.703 23.159 33.711 1.00 37.07 ? 168 CYS V C 1 ATOM 5147 O O . CYS D 2 168 ? 52.826 23.277 34.182 1.00 37.32 ? 168 CYS V O 1 ATOM 5148 C CB . CYS D 2 168 ? 51.196 25.532 33.256 1.00 37.06 ? 168 CYS V CB 1 ATOM 5149 S SG . CYS D 2 168 ? 50.266 27.166 33.216 1.00 40.48 ? 168 CYS V SG 1 ATOM 5150 N N . CYS D 2 169 ? 51.345 22.121 32.964 1.00 37.79 ? 169 CYS V N 1 ATOM 5151 C CA . CYS D 2 169 ? 52.304 21.092 32.591 1.00 38.81 ? 169 CYS V CA 1 ATOM 5152 C C . CYS D 2 169 ? 52.407 21.004 31.077 1.00 39.12 ? 169 CYS V C 1 ATOM 5153 O O . CYS D 2 169 ? 51.544 21.501 30.382 1.00 39.44 ? 169 CYS V O 1 ATOM 5154 C CB . CYS D 2 169 ? 51.876 19.749 33.161 1.00 39.13 ? 169 CYS V CB 1 ATOM 5155 S SG . CYS D 2 169 ? 50.683 18.851 32.122 1.00 40.59 ? 169 CYS V SG 1 ATOM 5156 N N . ASN D 2 170 ? 53.434 20.338 30.570 1.00 39.67 ? 170 ASN V N 1 ATOM 5157 C CA . ASN D 2 170 ? 53.713 20.347 29.142 1.00 40.50 ? 170 ASN V CA 1 ATOM 5158 C C . ASN D 2 170 ? 54.053 18.963 28.592 1.00 40.45 ? 170 ASN V C 1 ATOM 5159 O O . ASN D 2 170 ? 54.967 18.833 27.764 1.00 40.71 ? 170 ASN V O 1 ATOM 5160 C CB . ASN D 2 170 ? 54.854 21.334 28.857 1.00 41.07 ? 170 ASN V CB 1 ATOM 5161 C CG . ASN D 2 170 ? 55.982 21.236 29.882 1.00 44.37 ? 170 ASN V CG 1 ATOM 5162 O OD1 . ASN D 2 170 ? 56.059 20.264 30.638 1.00 45.63 ? 170 ASN V OD1 1 ATOM 5163 N ND2 . ASN D 2 170 ? 56.857 22.237 29.917 1.00 49.60 ? 170 ASN V ND2 1 ATOM 5164 N N . TYR D 2 171 ? 53.338 17.931 29.060 1.00 40.36 ? 171 TYR V N 1 ATOM 5165 C CA . TYR D 2 171 ? 53.552 16.543 28.590 1.00 39.96 ? 171 TYR V CA 1 ATOM 5166 C C . TYR D 2 171 ? 52.366 15.626 28.806 1.00 39.45 ? 171 TYR V C 1 ATOM 5167 O O . TYR D 2 171 ? 51.898 15.471 29.919 1.00 39.10 ? 171 TYR V O 1 ATOM 5168 C CB . TYR D 2 171 ? 54.792 15.927 29.221 1.00 40.15 ? 171 TYR V CB 1 ATOM 5169 C CG . TYR D 2 171 ? 54.747 15.749 30.719 1.00 41.08 ? 171 TYR V CG 1 ATOM 5170 C CD1 . TYR D 2 171 ? 55.358 16.672 31.560 1.00 42.26 ? 171 TYR V CD1 1 ATOM 5171 C CD2 . TYR D 2 171 ? 54.139 14.630 31.296 1.00 42.05 ? 171 TYR V CD2 1 ATOM 5172 C CE1 . TYR D 2 171 ? 55.352 16.501 32.940 1.00 43.34 ? 171 TYR V CE1 1 ATOM 5173 C CE2 . TYR D 2 171 ? 54.124 14.445 32.675 1.00 42.77 ? 171 TYR V CE2 1 ATOM 5174 C CZ . TYR D 2 171 ? 54.736 15.386 33.493 1.00 43.53 ? 171 TYR V CZ 1 ATOM 5175 O OH . TYR D 2 171 ? 54.736 15.218 34.863 1.00 44.28 ? 171 TYR V OH 1 ATOM 5176 N N . THR D 2 172 ? 51.918 14.988 27.730 1.00 39.30 ? 172 THR V N 1 ATOM 5177 C CA . THR D 2 172 ? 50.638 14.266 27.698 1.00 39.10 ? 172 THR V CA 1 ATOM 5178 C C . THR D 2 172 ? 50.109 13.874 29.057 1.00 38.81 ? 172 THR V C 1 ATOM 5179 O O . THR D 2 172 ? 50.769 13.187 29.824 1.00 38.97 ? 172 THR V O 1 ATOM 5180 C CB . THR D 2 172 ? 50.695 12.980 26.858 1.00 39.08 ? 172 THR V CB 1 ATOM 5181 O OG1 . THR D 2 172 ? 51.465 13.205 25.671 1.00 39.90 ? 172 THR V OG1 1 ATOM 5182 C CG2 . THR D 2 172 ? 49.286 12.527 26.488 1.00 38.70 ? 172 THR V CG2 1 ATOM 5183 N N . HIS D 2 173 ? 48.906 14.335 29.336 1.00 38.58 ? 173 HIS V N 1 ATOM 5184 C CA . HIS D 2 173 ? 48.132 13.871 30.462 1.00 38.43 ? 173 HIS V CA 1 ATOM 5185 C C . HIS D 2 173 ? 48.725 14.066 31.831 1.00 38.07 ? 173 HIS V C 1 ATOM 5186 O O . HIS D 2 173 ? 48.528 13.227 32.693 1.00 38.21 ? 173 HIS V O 1 ATOM 5187 C CB . HIS D 2 173 ? 47.754 12.412 30.267 1.00 38.50 ? 173 HIS V CB 1 ATOM 5188 C CG . HIS D 2 173 ? 46.310 12.232 29.982 1.00 40.12 ? 173 HIS V CG 1 ATOM 5189 N ND1 . HIS D 2 173 ? 45.781 12.397 28.722 1.00 41.44 ? 173 HIS V ND1 1 ATOM 5190 C CD2 . HIS D 2 173 ? 45.266 11.976 30.805 1.00 41.50 ? 173 HIS V CD2 1 ATOM 5191 C CE1 . HIS D 2 173 ? 44.473 12.218 28.774 1.00 42.60 ? 173 HIS V CE1 1 ATOM 5192 N NE2 . HIS D 2 173 ? 44.135 11.961 30.026 1.00 42.89 ? 173 HIS V NE2 1 ATOM 5193 N N . CYS D 2 174 ? 49.414 15.180 32.051 1.00 37.86 ? 174 CYS V N 1 ATOM 5194 C CA . CYS D 2 174 ? 50.027 15.424 33.366 1.00 37.72 ? 174 CYS V CA 1 ATOM 5195 C C . CYS D 2 174 ? 49.111 16.106 34.380 1.00 36.81 ? 174 CYS V C 1 ATOM 5196 O O . CYS D 2 174 ? 49.401 17.196 34.850 1.00 36.72 ? 174 CYS V O 1 ATOM 5197 C CB . CYS D 2 174 ? 51.382 16.147 33.255 1.00 38.12 ? 174 CYS V CB 1 ATOM 5198 S SG . CYS D 2 174 ? 51.660 17.115 31.745 1.00 40.23 ? 174 CYS V SG 1 ATOM 5199 N N . ASN D 2 175 ? 48.002 15.452 34.705 1.00 36.00 ? 175 ASN V N 1 ATOM 5200 C CA . ASN D 2 175 ? 47.134 15.885 35.798 1.00 35.43 ? 175 ASN V CA 1 ATOM 5201 C C . ASN D 2 175 ? 46.098 14.824 36.206 1.00 34.84 ? 175 ASN V C 1 ATOM 5202 O O . ASN D 2 175 ? 44.930 14.901 35.832 1.00 34.87 ? 175 ASN V O 1 ATOM 5203 C CB . ASN D 2 175 ? 46.492 17.257 35.505 1.00 35.57 ? 175 ASN V CB 1 ATOM 5204 C CG . ASN D 2 175 ? 45.915 17.369 34.099 1.00 35.99 ? 175 ASN V CG 1 ATOM 5205 O OD1 . ASN D 2 175 ? 44.743 17.699 33.932 1.00 37.63 ? 175 ASN V OD1 1 ATOM 5206 N ND2 . ASN D 2 175 ? 46.735 17.123 33.088 1.00 36.30 ? 175 ASN V ND2 1 ATOM 5207 N N . GLY D 2 176 ? 46.532 13.838 36.985 1.00 33.92 ? 176 GLY V N 1 ATOM 5208 C CA . GLY D 2 176 ? 45.720 12.659 37.213 1.00 32.98 ? 176 GLY V CA 1 ATOM 5209 C C . GLY D 2 176 ? 45.026 12.580 38.551 1.00 32.45 ? 176 GLY V C 1 ATOM 5210 O O . GLY D 2 176 ? 45.303 13.380 39.446 1.00 32.11 ? 176 GLY V O 1 ATOM 5211 N N . GLY D 2 177 ? 44.121 11.595 38.651 1.00 32.16 ? 177 GLY V N 1 ATOM 5212 C CA . GLY D 2 177 ? 43.350 11.239 39.857 1.00 31.24 ? 177 GLY V CA 1 ATOM 5213 C C . GLY D 2 177 ? 43.545 12.170 41.039 1.00 30.51 ? 177 GLY V C 1 ATOM 5214 O O . GLY D 2 177 ? 42.697 13.019 41.299 1.00 30.33 ? 177 GLY V O 1 ATOM 5215 N N . PRO D 2 178 ? 44.663 12.007 41.768 1.00 29.84 ? 178 PRO V N 1 ATOM 5216 C CA . PRO D 2 178 ? 45.075 12.997 42.726 1.00 29.35 ? 178 PRO V CA 1 ATOM 5217 C C . PRO D 2 178 ? 44.508 14.389 42.390 1.00 28.91 ? 178 PRO V C 1 ATOM 5218 O O . PRO D 2 178 ? 45.132 15.179 41.684 1.00 28.34 ? 178 PRO V O 1 ATOM 5219 C CB . PRO D 2 178 ? 46.606 12.976 42.587 1.00 29.50 ? 178 PRO V CB 1 ATOM 5220 C CG . PRO D 2 178 ? 46.946 11.665 41.882 1.00 29.25 ? 178 PRO V CG 1 ATOM 5221 C CD . PRO D 2 178 ? 45.659 10.930 41.678 1.00 29.68 ? 178 PRO V CD 1 ATOM 5222 N N . VAL D 2 179 ? 43.303 14.640 42.888 1.00 28.66 ? 179 VAL V N 1 ATOM 5223 C CA . VAL D 2 179 ? 42.669 15.956 42.887 1.00 28.54 ? 179 VAL V CA 1 ATOM 5224 C C . VAL D 2 179 ? 43.301 16.825 43.964 1.00 28.34 ? 179 VAL V C 1 ATOM 5225 O O . VAL D 2 179 ? 42.930 16.728 45.143 1.00 28.73 ? 179 VAL V O 1 ATOM 5226 C CB . VAL D 2 179 ? 41.174 15.832 43.205 1.00 28.63 ? 179 VAL V CB 1 ATOM 5227 C CG1 . VAL D 2 179 ? 40.426 15.336 41.995 1.00 29.60 ? 179 VAL V CG1 1 ATOM 5228 C CG2 . VAL D 2 179 ? 40.937 14.893 44.414 1.00 28.54 ? 179 VAL V CG2 1 ATOM 5229 N N . LEU D 2 180 ? 44.235 17.683 43.558 1.00 27.79 ? 180 LEU V N 1 ATOM 5230 C CA . LEU D 2 180 ? 45.196 18.324 44.480 1.00 27.31 ? 180 LEU V CA 1 ATOM 5231 C C . LEU D 2 180 ? 44.622 19.227 45.590 1.00 27.04 ? 180 LEU V C 1 ATOM 5232 O O . LEU D 2 180 ? 44.605 20.452 45.436 1.00 26.64 ? 180 LEU V O 1 ATOM 5233 C CB . LEU D 2 180 ? 46.278 19.080 43.687 1.00 27.05 ? 180 LEU V CB 1 ATOM 5234 C CG . LEU D 2 180 ? 46.817 18.460 42.383 1.00 27.29 ? 180 LEU V CG 1 ATOM 5235 C CD1 . LEU D 2 180 ? 47.926 19.337 41.786 1.00 26.40 ? 180 LEU V CD1 1 ATOM 5236 C CD2 . LEU D 2 180 ? 47.283 16.983 42.513 1.00 27.68 ? 180 LEU V CD2 1 ATOM 5237 N N . ASP D 2 181 ? 44.202 18.623 46.716 1.00 26.90 ? 181 ASP V N 1 ATOM 5238 C CA . ASP D 2 181 ? 43.695 19.392 47.881 1.00 26.38 ? 181 ASP V CA 1 ATOM 5239 C C . ASP D 2 181 ? 44.765 19.706 48.919 1.00 25.96 ? 181 ASP V C 1 ATOM 5240 O O . ASP D 2 181 ? 45.923 19.331 48.744 1.00 26.18 ? 181 ASP V O 1 ATOM 5241 C CB . ASP D 2 181 ? 42.465 18.748 48.532 1.00 26.33 ? 181 ASP V CB 1 ATOM 5242 C CG . ASP D 2 181 ? 42.772 17.453 49.241 1.00 26.28 ? 181 ASP V CG 1 ATOM 5243 O OD1 . ASP D 2 181 ? 41.898 16.563 49.176 1.00 27.31 ? 181 ASP V OD1 1 ATOM 5244 O OD2 . ASP D 2 181 ? 43.844 17.327 49.876 1.00 25.40 ? 181 ASP V OD2 1 ATOM 5245 N N . LEU D 2 182 ? 44.377 20.385 49.995 1.00 25.37 ? 182 LEU V N 1 ATOM 5246 C CA . LEU D 2 182 ? 45.359 20.929 50.934 1.00 25.02 ? 182 LEU V CA 1 ATOM 5247 C C . LEU D 2 182 ? 46.084 19.900 51.817 1.00 25.00 ? 182 LEU V C 1 ATOM 5248 O O . LEU D 2 182 ? 47.321 19.851 51.836 1.00 24.44 ? 182 LEU V O 1 ATOM 5249 C CB . LEU D 2 182 ? 44.738 22.042 51.772 1.00 24.75 ? 182 LEU V CB 1 ATOM 5250 C CG . LEU D 2 182 ? 45.730 23.133 52.166 1.00 23.73 ? 182 LEU V CG 1 ATOM 5251 C CD1 . LEU D 2 182 ? 46.841 23.263 51.128 1.00 22.52 ? 182 LEU V CD1 1 ATOM 5252 C CD2 . LEU D 2 182 ? 44.999 24.453 52.354 1.00 23.04 ? 182 LEU V CD2 1 ATOM 5253 N N . GLN D 2 183 ? 45.311 19.092 52.539 1.00 25.22 ? 183 GLN V N 1 ATOM 5254 C CA . GLN D 2 183 ? 45.831 17.941 53.265 1.00 25.73 ? 183 GLN V CA 1 ATOM 5255 C C . GLN D 2 183 ? 47.043 17.329 52.533 1.00 25.93 ? 183 GLN V C 1 ATOM 5256 O O . GLN D 2 183 ? 47.999 16.843 53.166 1.00 25.85 ? 183 GLN V O 1 ATOM 5257 C CB . GLN D 2 183 ? 44.689 16.923 53.460 1.00 25.88 ? 183 GLN V CB 1 ATOM 5258 C CG . GLN D 2 183 ? 45.062 15.424 53.470 1.00 26.49 ? 183 GLN V CG 1 ATOM 5259 C CD . GLN D 2 183 ? 45.756 14.984 54.745 1.00 27.57 ? 183 GLN V CD 1 ATOM 5260 O OE1 . GLN D 2 183 ? 45.121 14.455 55.663 1.00 28.34 ? 183 GLN V OE1 1 ATOM 5261 N NE2 . GLN D 2 183 ? 47.067 15.202 54.812 1.00 27.68 ? 183 GLN V NE2 1 ATOM 5262 N N . SER D 2 184 ? 46.996 17.406 51.200 1.00 26.03 ? 184 SER V N 1 ATOM 5263 C CA . SER D 2 184 ? 47.975 16.790 50.294 1.00 26.15 ? 184 SER V CA 1 ATOM 5264 C C . SER D 2 184 ? 49.380 17.414 50.300 1.00 25.79 ? 184 SER V C 1 ATOM 5265 O O . SER D 2 184 ? 50.298 16.867 49.699 1.00 25.60 ? 184 SER V O 1 ATOM 5266 C CB . SER D 2 184 ? 47.442 16.797 48.850 1.00 26.52 ? 184 SER V CB 1 ATOM 5267 O OG . SER D 2 184 ? 46.025 16.915 48.786 1.00 27.27 ? 184 SER V OG 1 ATOM 5268 N N . PHE D 2 185 ? 49.555 18.556 50.950 1.00 25.59 ? 185 PHE V N 1 ATOM 5269 C CA . PHE D 2 185 ? 50.873 19.187 50.970 1.00 25.56 ? 185 PHE V CA 1 ATOM 5270 C C . PHE D 2 185 ? 51.567 19.130 52.340 1.00 25.39 ? 185 PHE V C 1 ATOM 5271 O O . PHE D 2 185 ? 50.954 19.456 53.367 1.00 25.81 ? 185 PHE V O 1 ATOM 5272 C CB . PHE D 2 185 ? 50.786 20.635 50.489 1.00 25.74 ? 185 PHE V CB 1 ATOM 5273 C CG . PHE D 2 185 ? 50.623 20.775 49.002 1.00 25.82 ? 185 PHE V CG 1 ATOM 5274 C CD1 . PHE D 2 185 ? 51.708 20.564 48.148 1.00 25.45 ? 185 PHE V CD1 1 ATOM 5275 C CD2 . PHE D 2 185 ? 49.384 21.127 48.456 1.00 24.93 ? 185 PHE V CD2 1 ATOM 5276 C CE1 . PHE D 2 185 ? 51.563 20.702 46.781 1.00 25.39 ? 185 PHE V CE1 1 ATOM 5277 C CE2 . PHE D 2 185 ? 49.225 21.266 47.088 1.00 24.20 ? 185 PHE V CE2 1 ATOM 5278 C CZ . PHE D 2 185 ? 50.314 21.058 46.244 1.00 24.65 ? 185 PHE V CZ 1 ATOM 5279 N N . PRO D 2 186 ? 52.860 18.744 52.356 1.00 24.68 ? 186 PRO V N 1 ATOM 5280 C CA . PRO D 2 186 ? 53.598 18.696 53.606 1.00 24.15 ? 186 PRO V CA 1 ATOM 5281 C C . PRO D 2 186 ? 53.856 20.122 54.144 1.00 23.84 ? 186 PRO V C 1 ATOM 5282 O O . PRO D 2 186 ? 54.403 20.953 53.418 1.00 24.00 ? 186 PRO V O 1 ATOM 5283 C CB . PRO D 2 186 ? 54.913 18.046 53.185 1.00 24.11 ? 186 PRO V CB 1 ATOM 5284 C CG . PRO D 2 186 ? 55.118 18.502 51.779 1.00 23.97 ? 186 PRO V CG 1 ATOM 5285 C CD . PRO D 2 186 ? 53.747 18.574 51.185 1.00 24.47 ? 186 PRO V CD 1 ATOM 5286 N N . PRO D 2 187 ? 53.458 20.415 55.399 1.00 23.36 ? 187 PRO V N 1 ATOM 5287 C CA . PRO D 2 187 ? 53.793 21.736 55.930 1.00 22.97 ? 187 PRO V CA 1 ATOM 5288 C C . PRO D 2 187 ? 55.293 21.971 55.827 1.00 22.56 ? 187 PRO V C 1 ATOM 5289 O O . PRO D 2 187 ? 56.068 21.153 56.308 1.00 22.47 ? 187 PRO V O 1 ATOM 5290 C CB . PRO D 2 187 ? 53.361 21.648 57.397 1.00 23.07 ? 187 PRO V CB 1 ATOM 5291 C CG . PRO D 2 187 ? 52.330 20.581 57.436 1.00 23.01 ? 187 PRO V CG 1 ATOM 5292 C CD . PRO D 2 187 ? 52.733 19.591 56.384 1.00 23.42 ? 187 PRO V CD 1 ATOM 5293 N N . ASN D 2 188 ? 55.689 23.070 55.189 1.00 22.35 ? 188 ASN V N 1 ATOM 5294 C CA . ASN D 2 188 ? 57.106 23.315 54.863 1.00 22.15 ? 188 ASN V CA 1 ATOM 5295 C C . ASN D 2 188 ? 57.985 23.893 55.979 1.00 22.15 ? 188 ASN V C 1 ATOM 5296 O O . ASN D 2 188 ? 59.215 23.885 55.858 1.00 22.06 ? 188 ASN V O 1 ATOM 5297 C CB . ASN D 2 188 ? 57.254 24.142 53.573 1.00 22.01 ? 188 ASN V CB 1 ATOM 5298 C CG . ASN D 2 188 ? 56.360 25.371 53.552 1.00 20.94 ? 188 ASN V CG 1 ATOM 5299 O OD1 . ASN D 2 188 ? 55.244 25.351 54.053 1.00 17.63 ? 188 ASN V OD1 1 ATOM 5300 N ND2 . ASN D 2 188 ? 56.852 26.444 52.948 1.00 21.17 ? 188 ASN V ND2 1 ATOM 5301 N N . GLY D 2 189 ? 57.356 24.385 57.050 1.00 22.18 ? 189 GLY V N 1 ATOM 5302 C CA . GLY D 2 189 ? 58.078 24.816 58.255 1.00 22.25 ? 189 GLY V CA 1 ATOM 5303 C C . GLY D 2 189 ? 58.109 26.313 58.462 1.00 22.16 ? 189 GLY V C 1 ATOM 5304 O O . GLY D 2 189 ? 58.462 26.807 59.533 1.00 21.89 ? 189 GLY V O 1 ATOM 5305 N N . PHE D 2 190 ? 57.752 27.033 57.412 1.00 22.42 ? 190 PHE V N 1 ATOM 5306 C CA . PHE D 2 190 ? 57.559 28.457 57.498 1.00 22.83 ? 190 PHE V CA 1 ATOM 5307 C C . PHE D 2 190 ? 56.188 28.669 58.132 1.00 23.33 ? 190 PHE V C 1 ATOM 5308 O O . PHE D 2 190 ? 55.406 27.716 58.298 1.00 23.33 ? 190 PHE V O 1 ATOM 5309 C CB . PHE D 2 190 ? 57.625 29.084 56.100 1.00 22.48 ? 190 PHE V CB 1 ATOM 5310 C CG . PHE D 2 190 ? 58.910 28.798 55.357 1.00 22.80 ? 190 PHE V CG 1 ATOM 5311 C CD1 . PHE D 2 190 ? 59.803 29.823 55.066 1.00 23.29 ? 190 PHE V CD1 1 ATOM 5312 C CD2 . PHE D 2 190 ? 59.228 27.506 54.935 1.00 23.51 ? 190 PHE V CD2 1 ATOM 5313 C CE1 . PHE D 2 190 ? 61.006 29.567 54.371 1.00 23.22 ? 190 PHE V CE1 1 ATOM 5314 C CE2 . PHE D 2 190 ? 60.425 27.237 54.241 1.00 23.39 ? 190 PHE V CE2 1 ATOM 5315 C CZ . PHE D 2 190 ? 61.314 28.273 53.960 1.00 22.97 ? 190 PHE V CZ 1 ATOM 5316 N N . GLN D 2 191 ? 55.913 29.909 58.522 1.00 23.92 ? 191 GLN V N 1 ATOM 5317 C CA . GLN D 2 191 ? 54.568 30.323 58.928 1.00 24.65 ? 191 GLN V CA 1 ATOM 5318 C C . GLN D 2 191 ? 54.348 31.774 58.522 1.00 25.22 ? 191 GLN V C 1 ATOM 5319 O O . GLN D 2 191 ? 55.301 32.540 58.456 1.00 25.62 ? 191 GLN V O 1 ATOM 5320 C CB . GLN D 2 191 ? 54.375 30.214 60.431 1.00 24.62 ? 191 GLN V CB 1 ATOM 5321 C CG . GLN D 2 191 ? 55.288 29.256 61.152 1.00 24.66 ? 191 GLN V CG 1 ATOM 5322 C CD . GLN D 2 191 ? 55.445 29.639 62.600 1.00 24.32 ? 191 GLN V CD 1 ATOM 5323 O OE1 . GLN D 2 191 ? 56.561 29.799 63.098 1.00 23.74 ? 191 GLN V OE1 1 ATOM 5324 N NE2 . GLN D 2 191 ? 54.319 29.815 63.285 1.00 24.15 ? 191 GLN V NE2 1 ATOM 5325 N N . CYS D 2 192 ? 53.105 32.154 58.236 1.00 25.92 ? 192 CYS V N 1 ATOM 5326 C CA . CYS D 2 192 ? 52.782 33.549 57.907 1.00 26.56 ? 192 CYS V CA 1 ATOM 5327 C C . CYS D 2 192 ? 51.447 33.898 58.532 1.00 26.88 ? 192 CYS V C 1 ATOM 5328 O O . CYS D 2 192 ? 50.674 33.003 58.889 1.00 27.17 ? 192 CYS V O 1 ATOM 5329 C CB . CYS D 2 192 ? 52.730 33.775 56.397 1.00 26.57 ? 192 CYS V CB 1 ATOM 5330 S SG . CYS D 2 192 ? 54.199 33.220 55.473 1.00 27.82 ? 192 CYS V SG 1 ATOM 5331 N N . TYR D 2 193 ? 51.182 35.189 58.688 1.00 27.13 ? 193 TYR V N 1 ATOM 5332 C CA . TYR D 2 193 ? 49.960 35.614 59.330 1.00 27.60 ? 193 TYR V CA 1 ATOM 5333 C C . TYR D 2 193 ? 48.884 35.534 58.301 1.00 28.12 ? 193 TYR V C 1 ATOM 5334 O O . TYR D 2 193 ? 48.827 36.346 57.393 1.00 27.84 ? 193 TYR V O 1 ATOM 5335 C CB . TYR D 2 193 ? 50.075 37.038 59.850 1.00 27.47 ? 193 TYR V CB 1 ATOM 5336 C CG . TYR D 2 193 ? 51.079 37.183 60.938 1.00 27.83 ? 193 TYR V CG 1 ATOM 5337 C CD1 . TYR D 2 193 ? 50.722 36.977 62.269 1.00 28.75 ? 193 TYR V CD1 1 ATOM 5338 C CD2 . TYR D 2 193 ? 52.400 37.508 60.649 1.00 28.57 ? 193 TYR V CD2 1 ATOM 5339 C CE1 . TYR D 2 193 ? 51.654 37.108 63.293 1.00 28.35 ? 193 TYR V CE1 1 ATOM 5340 C CE2 . TYR D 2 193 ? 53.343 37.627 61.661 1.00 28.97 ? 193 TYR V CE2 1 ATOM 5341 C CZ . TYR D 2 193 ? 52.962 37.430 62.980 1.00 28.94 ? 193 TYR V CZ 1 ATOM 5342 O OH . TYR D 2 193 ? 53.898 37.559 63.982 1.00 30.19 ? 193 TYR V OH 1 ATOM 5343 N N . SER D 2 194 ? 48.047 34.524 58.427 1.00 29.37 ? 194 SER V N 1 ATOM 5344 C CA . SER D 2 194 ? 46.916 34.409 57.547 1.00 30.87 ? 194 SER V CA 1 ATOM 5345 C C . SER D 2 194 ? 45.795 35.278 58.059 1.00 32.02 ? 194 SER V C 1 ATOM 5346 O O . SER D 2 194 ? 45.666 35.501 59.269 1.00 32.02 ? 194 SER V O 1 ATOM 5347 C CB . SER D 2 194 ? 46.426 32.983 57.464 1.00 30.74 ? 194 SER V CB 1 ATOM 5348 O OG . SER D 2 194 ? 45.065 32.985 57.077 1.00 31.18 ? 194 SER V OG 1 ATOM 5349 N N . CYS D 2 195 ? 44.971 35.746 57.122 1.00 33.58 ? 195 CYS V N 1 ATOM 5350 C CA . CYS D 2 195 ? 43.850 36.612 57.445 1.00 34.92 ? 195 CYS V CA 1 ATOM 5351 C C . CYS D 2 195 ? 43.027 37.028 56.219 1.00 35.05 ? 195 CYS V C 1 ATOM 5352 O O . CYS D 2 195 ? 43.570 37.218 55.131 1.00 34.77 ? 195 CYS V O 1 ATOM 5353 C CB . CYS D 2 195 ? 44.367 37.829 58.212 1.00 35.12 ? 195 CYS V CB 1 ATOM 5354 S SG . CYS D 2 195 ? 43.495 39.345 57.924 1.00 38.19 ? 195 CYS V SG 1 ATOM 5355 N N . GLU D 2 196 ? 41.708 37.099 56.430 1.00 35.75 ? 196 GLU V N 1 ATOM 5356 C CA . GLU D 2 196 ? 40.728 37.782 55.561 1.00 36.39 ? 196 GLU V CA 1 ATOM 5357 C C . GLU D 2 196 ? 39.352 37.812 56.251 1.00 37.02 ? 196 GLU V C 1 ATOM 5358 O O . GLU D 2 196 ? 38.568 36.859 56.133 1.00 37.00 ? 196 GLU V O 1 ATOM 5359 C CB . GLU D 2 196 ? 40.630 37.161 54.151 1.00 36.27 ? 196 GLU V CB 1 ATOM 5360 C CG . GLU D 2 196 ? 39.404 37.621 53.299 1.00 35.39 ? 196 GLU V CG 1 ATOM 5361 C CD . GLU D 2 196 ? 39.097 39.117 53.388 1.00 34.30 ? 196 GLU V CD 1 ATOM 5362 O OE1 . GLU D 2 196 ? 37.947 39.487 53.703 1.00 33.98 ? 196 GLU V OE1 1 ATOM 5363 O OE2 . GLU D 2 196 ? 40.004 39.928 53.146 1.00 34.64 ? 196 GLU V OE2 1 ATOM 5364 N N . GLY D 2 197 ? 39.068 38.907 56.968 1.00 37.70 ? 197 GLY V N 1 ATOM 5365 C CA . GLY D 2 197 ? 37.791 39.057 57.691 1.00 38.14 ? 197 GLY V CA 1 ATOM 5366 C C . GLY D 2 197 ? 37.494 40.396 58.343 1.00 38.38 ? 197 GLY V C 1 ATOM 5367 O O . GLY D 2 197 ? 36.438 40.546 58.955 1.00 38.18 ? 197 GLY V O 1 ATOM 5368 N N . ASN D 2 198 ? 38.416 41.358 58.206 1.00 38.91 ? 198 ASN V N 1 ATOM 5369 C CA . ASN D 2 198 ? 38.302 42.694 58.833 1.00 39.48 ? 198 ASN V CA 1 ATOM 5370 C C . ASN D 2 198 ? 39.026 43.873 58.123 1.00 39.94 ? 198 ASN V C 1 ATOM 5371 O O . ASN D 2 198 ? 38.582 44.328 57.066 1.00 39.78 ? 198 ASN V O 1 ATOM 5372 C CB . ASN D 2 198 ? 38.701 42.630 60.318 1.00 39.36 ? 198 ASN V CB 1 ATOM 5373 C CG . ASN D 2 198 ? 37.522 42.808 61.253 1.00 39.29 ? 198 ASN V CG 1 ATOM 5374 O OD1 . ASN D 2 198 ? 37.676 42.759 62.468 1.00 39.42 ? 198 ASN V OD1 1 ATOM 5375 N ND2 . ASN D 2 198 ? 36.339 43.034 60.692 1.00 39.15 ? 198 ASN V ND2 1 ATOM 5376 N N . ASN D 2 199 ? 40.111 44.371 58.736 1.00 40.67 ? 199 ASN V N 1 ATOM 5377 C CA . ASN D 2 199 ? 40.919 45.520 58.237 1.00 41.17 ? 199 ASN V CA 1 ATOM 5378 C C . ASN D 2 199 ? 42.151 45.894 59.136 1.00 41.30 ? 199 ASN V C 1 ATOM 5379 O O . ASN D 2 199 ? 43.072 45.069 59.323 1.00 41.43 ? 199 ASN V O 1 ATOM 5380 C CB . ASN D 2 199 ? 40.029 46.755 57.957 1.00 41.24 ? 199 ASN V CB 1 ATOM 5381 C CG . ASN D 2 199 ? 40.781 47.892 57.248 1.00 41.79 ? 199 ASN V CG 1 ATOM 5382 O OD1 . ASN D 2 199 ? 40.439 49.072 57.412 1.00 42.54 ? 199 ASN V OD1 1 ATOM 5383 N ND2 . ASN D 2 199 ? 41.807 47.542 56.466 1.00 41.65 ? 199 ASN V ND2 1 ATOM 5384 N N . THR D 2 200 ? 42.159 47.127 59.666 1.00 40.99 ? 200 THR V N 1 ATOM 5385 C CA . THR D 2 200 ? 43.287 47.671 60.447 1.00 40.69 ? 200 THR V CA 1 ATOM 5386 C C . THR D 2 200 ? 43.020 47.642 61.962 1.00 40.45 ? 200 THR V C 1 ATOM 5387 O O . THR D 2 200 ? 43.770 48.226 62.765 1.00 40.51 ? 200 THR V O 1 ATOM 5388 C CB . THR D 2 200 ? 43.699 49.101 59.987 1.00 40.74 ? 200 THR V CB 1 ATOM 5389 O OG1 . THR D 2 200 ? 42.526 49.879 59.718 1.00 40.80 ? 200 THR V OG1 1 ATOM 5390 C CG2 . THR D 2 200 ? 44.578 49.045 58.734 1.00 40.63 ? 200 THR V CG2 1 ATOM 5391 N N . LEU D 2 201 ? 41.924 46.981 62.327 1.00 39.85 ? 201 LEU V N 1 ATOM 5392 C CA . LEU D 2 201 ? 41.729 46.406 63.661 1.00 39.06 ? 201 LEU V CA 1 ATOM 5393 C C . LEU D 2 201 ? 40.779 45.212 63.491 1.00 38.80 ? 201 LEU V C 1 ATOM 5394 O O . LEU D 2 201 ? 39.872 45.230 62.651 1.00 38.71 ? 201 LEU V O 1 ATOM 5395 C CB . LEU D 2 201 ? 41.290 47.442 64.723 1.00 38.69 ? 201 LEU V CB 1 ATOM 5396 C CG . LEU D 2 201 ? 39.881 48.003 64.922 1.00 37.91 ? 201 LEU V CG 1 ATOM 5397 C CD1 . LEU D 2 201 ? 39.821 48.672 66.283 1.00 37.19 ? 201 LEU V CD1 1 ATOM 5398 C CD2 . LEU D 2 201 ? 39.481 48.977 63.820 1.00 37.10 ? 201 LEU V CD2 1 ATOM 5399 N N . GLY D 2 202 ? 41.034 44.154 64.252 1.00 38.42 ? 202 GLY V N 1 ATOM 5400 C CA . GLY D 2 202 ? 40.416 42.860 63.995 1.00 37.96 ? 202 GLY V CA 1 ATOM 5401 C C . GLY D 2 202 ? 41.381 41.965 63.232 1.00 37.59 ? 202 GLY V C 1 ATOM 5402 O O . GLY D 2 202 ? 41.954 41.025 63.796 1.00 37.56 ? 202 GLY V O 1 ATOM 5403 N N . CYS D 2 203 ? 41.567 42.262 61.948 1.00 37.03 ? 203 CYS V N 1 ATOM 5404 C CA . CYS D 2 203 ? 42.527 41.533 61.125 1.00 36.53 ? 203 CYS V CA 1 ATOM 5405 C C . CYS D 2 203 ? 43.808 42.371 60.945 1.00 35.58 ? 203 CYS V C 1 ATOM 5406 O O . CYS D 2 203 ? 44.471 42.343 59.897 1.00 35.40 ? 203 CYS V O 1 ATOM 5407 C CB . CYS D 2 203 ? 41.884 41.138 59.790 1.00 36.83 ? 203 CYS V CB 1 ATOM 5408 S SG . CYS D 2 203 ? 42.027 39.354 59.355 1.00 38.98 ? 203 CYS V SG 1 ATOM 5409 N N . SER D 2 204 ? 44.132 43.121 61.998 1.00 34.52 ? 204 SER V N 1 ATOM 5410 C CA . SER D 2 204 ? 45.356 43.908 62.079 1.00 33.59 ? 204 SER V CA 1 ATOM 5411 C C . SER D 2 204 ? 46.404 43.099 62.831 1.00 33.16 ? 204 SER V C 1 ATOM 5412 O O . SER D 2 204 ? 46.587 41.909 62.549 1.00 33.34 ? 204 SER V O 1 ATOM 5413 C CB . SER D 2 204 ? 45.097 45.227 62.812 1.00 33.52 ? 204 SER V CB 1 ATOM 5414 O OG . SER D 2 204 ? 44.768 45.015 64.175 1.00 32.36 ? 204 SER V OG 1 ATOM 5415 N N . SER D 2 205 ? 47.090 43.750 63.779 1.00 32.28 ? 205 SER V N 1 ATOM 5416 C CA . SER D 2 205 ? 47.922 43.057 64.771 1.00 31.12 ? 205 SER V CA 1 ATOM 5417 C C . SER D 2 205 ? 47.018 42.566 65.906 1.00 30.62 ? 205 SER V C 1 ATOM 5418 O O . SER D 2 205 ? 47.485 42.045 66.915 1.00 30.09 ? 205 SER V O 1 ATOM 5419 C CB . SER D 2 205 ? 49.019 43.979 65.297 1.00 31.03 ? 205 SER V CB 1 ATOM 5420 O OG . SER D 2 205 ? 49.876 44.416 64.261 1.00 29.71 ? 205 SER V OG 1 ATOM 5421 N N . GLU D 2 206 ? 45.713 42.762 65.706 1.00 30.20 ? 206 GLU V N 1 ATOM 5422 C CA . GLU D 2 206 ? 44.654 42.220 66.546 1.00 29.80 ? 206 GLU V CA 1 ATOM 5423 C C . GLU D 2 206 ? 44.470 40.727 66.252 1.00 29.61 ? 206 GLU V C 1 ATOM 5424 O O . GLU D 2 206 ? 43.355 40.220 66.091 1.00 29.45 ? 206 GLU V O 1 ATOM 5425 C CB . GLU D 2 206 ? 43.353 43.015 66.345 1.00 29.76 ? 206 GLU V CB 1 ATOM 5426 C CG . GLU D 2 206 ? 42.130 42.538 67.153 1.00 29.57 ? 206 GLU V CG 1 ATOM 5427 C CD . GLU D 2 206 ? 42.167 42.898 68.633 1.00 29.30 ? 206 GLU V CD 1 ATOM 5428 O OE1 . GLU D 2 206 ? 43.260 43.181 69.174 1.00 29.58 ? 206 GLU V OE1 1 ATOM 5429 O OE2 . GLU D 2 206 ? 41.086 42.884 69.262 1.00 28.82 ? 206 GLU V OE2 1 ATOM 5430 N N . GLU D 2 207 ? 45.601 40.036 66.169 1.00 29.47 ? 207 GLU V N 1 ATOM 5431 C CA . GLU D 2 207 ? 45.654 38.579 66.251 1.00 29.21 ? 207 GLU V CA 1 ATOM 5432 C C . GLU D 2 207 ? 44.904 37.878 65.133 1.00 28.72 ? 207 GLU V C 1 ATOM 5433 O O . GLU D 2 207 ? 44.095 36.984 65.387 1.00 28.65 ? 207 GLU V O 1 ATOM 5434 C CB . GLU D 2 207 ? 45.155 38.094 67.628 1.00 29.44 ? 207 GLU V CB 1 ATOM 5435 C CG . GLU D 2 207 ? 45.922 38.663 68.824 1.00 29.42 ? 207 GLU V CG 1 ATOM 5436 C CD . GLU D 2 207 ? 45.844 40.184 68.899 1.00 29.54 ? 207 GLU V CD 1 ATOM 5437 O OE1 . GLU D 2 207 ? 46.828 40.850 68.524 1.00 29.63 ? 207 GLU V OE1 1 ATOM 5438 O OE2 . GLU D 2 207 ? 44.786 40.720 69.287 1.00 29.41 ? 207 GLU V OE2 1 ATOM 5439 N N . ALA D 2 208 ? 45.172 38.288 63.898 1.00 28.26 ? 208 ALA V N 1 ATOM 5440 C CA . ALA D 2 208 ? 44.686 37.528 62.745 1.00 27.98 ? 208 ALA V CA 1 ATOM 5441 C C . ALA D 2 208 ? 45.598 36.317 62.547 1.00 27.56 ? 208 ALA V C 1 ATOM 5442 O O . ALA D 2 208 ? 46.746 36.436 62.105 1.00 27.69 ? 208 ALA V O 1 ATOM 5443 C CB . ALA D 2 208 ? 44.624 38.385 61.501 1.00 27.99 ? 208 ALA V CB 1 ATOM 5444 N N . SER D 2 209 ? 45.067 35.157 62.903 1.00 26.74 ? 209 SER V N 1 ATOM 5445 C CA . SER D 2 209 ? 45.830 33.926 63.045 1.00 26.02 ? 209 SER V CA 1 ATOM 5446 C C . SER D 2 209 ? 47.244 33.858 62.450 1.00 25.59 ? 209 SER V C 1 ATOM 5447 O O . SER D 2 209 ? 47.594 34.543 61.485 1.00 25.05 ? 209 SER V O 1 ATOM 5448 C CB . SER D 2 209 ? 44.988 32.754 62.539 1.00 26.11 ? 209 SER V CB 1 ATOM 5449 O OG . SER D 2 209 ? 43.715 32.771 63.158 1.00 25.75 ? 209 SER V OG 1 ATOM 5450 N N . LEU D 2 210 ? 48.050 33.016 63.078 1.00 25.40 ? 210 LEU V N 1 ATOM 5451 C CA . LEU D 2 210 ? 49.268 32.510 62.492 1.00 25.31 ? 210 LEU V CA 1 ATOM 5452 C C . LEU D 2 210 ? 48.895 31.241 61.750 1.00 25.31 ? 210 LEU V C 1 ATOM 5453 O O . LEU D 2 210 ? 47.982 30.540 62.169 1.00 25.47 ? 210 LEU V O 1 ATOM 5454 C CB . LEU D 2 210 ? 50.227 32.123 63.601 1.00 25.19 ? 210 LEU V CB 1 ATOM 5455 C CG . LEU D 2 210 ? 51.703 32.432 63.414 1.00 25.26 ? 210 LEU V CG 1 ATOM 5456 C CD1 . LEU D 2 210 ? 52.148 32.444 61.951 1.00 24.77 ? 210 LEU V CD1 1 ATOM 5457 C CD2 . LEU D 2 210 ? 51.943 33.771 64.055 1.00 26.23 ? 210 LEU V CD2 1 ATOM 5458 N N . ILE D 2 211 ? 49.575 30.936 60.651 1.00 25.26 ? 211 ILE V N 1 ATOM 5459 C CA . ILE D 2 211 ? 49.388 29.632 60.012 1.00 25.48 ? 211 ILE V CA 1 ATOM 5460 C C . ILE D 2 211 ? 50.710 29.159 59.468 1.00 25.65 ? 211 ILE V C 1 ATOM 5461 O O . ILE D 2 211 ? 51.492 29.969 58.959 1.00 25.56 ? 211 ILE V O 1 ATOM 5462 C CB . ILE D 2 211 ? 48.333 29.620 58.851 1.00 25.59 ? 211 ILE V CB 1 ATOM 5463 C CG1 . ILE D 2 211 ? 48.846 30.381 57.621 1.00 25.17 ? 211 ILE V CG1 1 ATOM 5464 C CG2 . ILE D 2 211 ? 46.943 30.121 59.322 1.00 25.98 ? 211 ILE V CG2 1 ATOM 5465 C CD1 . ILE D 2 211 ? 48.244 29.936 56.328 1.00 24.20 ? 211 ILE V CD1 1 ATOM 5466 N N . ASN D 2 212 ? 50.955 27.852 59.598 1.00 25.83 ? 212 ASN V N 1 ATOM 5467 C CA . ASN D 2 212 ? 52.118 27.199 58.990 1.00 25.70 ? 212 ASN V CA 1 ATOM 5468 C C . ASN D 2 212 ? 51.776 26.992 57.547 1.00 25.56 ? 212 ASN V C 1 ATOM 5469 O O . ASN D 2 212 ? 50.652 26.589 57.220 1.00 25.38 ? 212 ASN V O 1 ATOM 5470 C CB . ASN D 2 212 ? 52.417 25.841 59.629 1.00 25.68 ? 212 ASN V CB 1 ATOM 5471 C CG . ASN D 2 212 ? 52.502 25.915 61.131 1.00 25.97 ? 212 ASN V CG 1 ATOM 5472 O OD1 . ASN D 2 212 ? 53.362 26.603 61.673 1.00 26.98 ? 212 ASN V OD1 1 ATOM 5473 N ND2 . ASN D 2 212 ? 51.601 25.217 61.819 1.00 25.87 ? 212 ASN V ND2 1 ATOM 5474 N N . CYS D 2 213 ? 52.740 27.282 56.686 1.00 25.34 ? 213 CYS V N 1 ATOM 5475 C CA . CYS D 2 213 ? 52.515 27.192 55.259 1.00 25.46 ? 213 CYS V CA 1 ATOM 5476 C C . CYS D 2 213 ? 52.766 25.769 54.746 1.00 24.96 ? 213 CYS V C 1 ATOM 5477 O O . CYS D 2 213 ? 53.484 24.993 55.388 1.00 24.78 ? 213 CYS V O 1 ATOM 5478 C CB . CYS D 2 213 ? 53.381 28.221 54.539 1.00 25.66 ? 213 CYS V CB 1 ATOM 5479 S SG . CYS D 2 213 ? 53.178 29.939 55.157 1.00 27.59 ? 213 CYS V SG 1 ATOM 5480 N N . ARG D 2 214 ? 52.158 25.428 53.605 1.00 24.42 ? 214 ARG V N 1 ATOM 5481 C CA . ARG D 2 214 ? 52.310 24.094 53.002 1.00 23.85 ? 214 ARG V CA 1 ATOM 5482 C C . ARG D 2 214 ? 52.862 24.124 51.571 1.00 23.71 ? 214 ARG V C 1 ATOM 5483 O O . ARG D 2 214 ? 53.013 25.190 50.973 1.00 23.49 ? 214 ARG V O 1 ATOM 5484 C CB . ARG D 2 214 ? 50.994 23.319 53.049 1.00 23.53 ? 214 ARG V CB 1 ATOM 5485 C CG . ARG D 2 214 ? 50.129 23.666 54.241 1.00 22.78 ? 214 ARG V CG 1 ATOM 5486 C CD . ARG D 2 214 ? 49.109 22.600 54.516 1.00 21.82 ? 214 ARG V CD 1 ATOM 5487 N NE . ARG D 2 214 ? 49.706 21.444 55.170 1.00 22.31 ? 214 ARG V NE 1 ATOM 5488 C CZ . ARG D 2 214 ? 49.016 20.550 55.867 1.00 23.54 ? 214 ARG V CZ 1 ATOM 5489 N NH1 . ARG D 2 214 ? 47.703 20.673 56.002 1.00 24.26 ? 214 ARG V NH1 1 ATOM 5490 N NH2 . ARG D 2 214 ? 49.634 19.528 56.435 1.00 25.04 ? 214 ARG V NH2 1 ATOM 5491 N N . GLY D 2 215 ? 53.179 22.945 51.043 1.00 23.60 ? 215 GLY V N 1 ATOM 5492 C CA . GLY D 2 215 ? 53.695 22.803 49.682 1.00 23.66 ? 215 GLY V CA 1 ATOM 5493 C C . GLY D 2 215 ? 54.826 23.745 49.306 1.00 23.64 ? 215 GLY V C 1 ATOM 5494 O O . GLY D 2 215 ? 55.750 23.931 50.089 1.00 23.67 ? 215 GLY V O 1 ATOM 5495 N N . PRO D 2 216 ? 54.744 24.366 48.107 1.00 23.77 ? 216 PRO V N 1 ATOM 5496 C CA . PRO D 2 216 ? 55.809 25.182 47.549 1.00 23.66 ? 216 PRO V CA 1 ATOM 5497 C C . PRO D 2 216 ? 55.667 26.614 48.007 1.00 23.71 ? 216 PRO V C 1 ATOM 5498 O O . PRO D 2 216 ? 56.236 27.516 47.393 1.00 23.66 ? 216 PRO V O 1 ATOM 5499 C CB . PRO D 2 216 ? 55.512 25.120 46.059 1.00 23.55 ? 216 PRO V CB 1 ATOM 5500 C CG . PRO D 2 216 ? 54.021 25.149 46.014 1.00 23.60 ? 216 PRO V CG 1 ATOM 5501 C CD . PRO D 2 216 ? 53.540 24.427 47.251 1.00 24.01 ? 216 PRO V CD 1 ATOM 5502 N N . MET D 2 217 ? 54.907 26.808 49.082 1.00 23.89 ? 217 MET V N 1 ATOM 5503 C CA . MET D 2 217 ? 54.509 28.141 49.532 1.00 24.10 ? 217 MET V CA 1 ATOM 5504 C C . MET D 2 217 ? 55.268 28.604 50.775 1.00 23.52 ? 217 MET V C 1 ATOM 5505 O O . MET D 2 217 ? 54.908 28.300 51.904 1.00 23.28 ? 217 MET V O 1 ATOM 5506 C CB . MET D 2 217 ? 52.985 28.205 49.719 1.00 24.49 ? 217 MET V CB 1 ATOM 5507 C CG . MET D 2 217 ? 52.225 27.597 48.531 1.00 25.74 ? 217 MET V CG 1 ATOM 5508 S SD . MET D 2 217 ? 50.423 27.548 48.647 1.00 28.60 ? 217 MET V SD 1 ATOM 5509 C CE . MET D 2 217 ? 50.111 26.084 47.638 1.00 26.04 ? 217 MET V CE 1 ATOM 5510 N N . ASN D 2 218 ? 56.328 29.353 50.539 1.00 23.06 ? 218 ASN V N 1 ATOM 5511 C CA . ASN D 2 218 ? 57.196 29.766 51.601 1.00 22.97 ? 218 ASN V CA 1 ATOM 5512 C C . ASN D 2 218 ? 57.444 31.267 51.584 1.00 23.29 ? 218 ASN V C 1 ATOM 5513 O O . ASN D 2 218 ? 58.385 31.755 52.224 1.00 23.80 ? 218 ASN V O 1 ATOM 5514 C CB . ASN D 2 218 ? 58.508 28.990 51.533 1.00 22.81 ? 218 ASN V CB 1 ATOM 5515 C CG . ASN D 2 218 ? 58.965 28.729 50.109 1.00 22.30 ? 218 ASN V CG 1 ATOM 5516 O OD1 . ASN D 2 218 ? 59.915 29.353 49.615 1.00 20.79 ? 218 ASN V OD1 1 ATOM 5517 N ND2 . ASN D 2 218 ? 58.297 27.790 49.442 1.00 21.87 ? 218 ASN V ND2 1 ATOM 5518 N N . GLN D 2 219 ? 56.607 32.000 50.851 1.00 23.20 ? 219 GLN V N 1 ATOM 5519 C CA . GLN D 2 219 ? 56.623 33.460 50.909 1.00 22.96 ? 219 GLN V CA 1 ATOM 5520 C C . GLN D 2 219 ? 55.426 33.907 51.694 1.00 22.98 ? 219 GLN V C 1 ATOM 5521 O O . GLN D 2 219 ? 54.344 33.320 51.587 1.00 22.70 ? 219 GLN V O 1 ATOM 5522 C CB . GLN D 2 219 ? 56.537 34.078 49.522 1.00 22.95 ? 219 GLN V CB 1 ATOM 5523 C CG . GLN D 2 219 ? 57.334 33.366 48.479 1.00 22.82 ? 219 GLN V CG 1 ATOM 5524 C CD . GLN D 2 219 ? 58.794 33.532 48.697 1.00 22.62 ? 219 GLN V CD 1 ATOM 5525 O OE1 . GLN D 2 219 ? 59.331 34.624 48.534 1.00 23.28 ? 219 GLN V OE1 1 ATOM 5526 N NE2 . GLN D 2 219 ? 59.460 32.450 49.071 1.00 22.72 ? 219 GLN V NE2 1 ATOM 5527 N N . CYS D 2 220 ? 55.616 34.947 52.489 1.00 23.37 ? 220 CYS V N 1 ATOM 5528 C CA . CYS D 2 220 ? 54.493 35.580 53.159 1.00 24.06 ? 220 CYS V CA 1 ATOM 5529 C C . CYS D 2 220 ? 53.986 36.709 52.287 1.00 24.24 ? 220 CYS V C 1 ATOM 5530 O O . CYS D 2 220 ? 54.753 37.316 51.538 1.00 24.83 ? 220 CYS V O 1 ATOM 5531 C CB . CYS D 2 220 ? 54.898 36.079 54.529 1.00 23.83 ? 220 CYS V CB 1 ATOM 5532 S SG . CYS D 2 220 ? 55.544 34.772 55.589 1.00 25.70 ? 220 CYS V SG 1 ATOM 5533 N N . LEU D 2 221 ? 52.689 36.974 52.347 1.00 24.14 ? 221 LEU V N 1 ATOM 5534 C CA . LEU D 2 221 ? 52.103 37.939 51.434 1.00 23.98 ? 221 LEU V CA 1 ATOM 5535 C C . LEU D 2 221 ? 51.034 38.834 52.081 1.00 24.21 ? 221 LEU V C 1 ATOM 5536 O O . LEU D 2 221 ? 50.158 38.354 52.826 1.00 24.38 ? 221 LEU V O 1 ATOM 5537 C CB . LEU D 2 221 ? 51.548 37.217 50.194 1.00 23.75 ? 221 LEU V CB 1 ATOM 5538 C CG . LEU D 2 221 ? 50.939 38.007 49.020 1.00 23.64 ? 221 LEU V CG 1 ATOM 5539 C CD1 . LEU D 2 221 ? 51.239 37.344 47.673 1.00 23.36 ? 221 LEU V CD1 1 ATOM 5540 C CD2 . LEU D 2 221 ? 49.434 38.253 49.189 1.00 22.27 ? 221 LEU V CD2 1 ATOM 5541 N N . VAL D 2 222 ? 51.129 40.135 51.779 1.00 23.89 ? 222 VAL V N 1 ATOM 5542 C CA . VAL D 2 222 ? 50.075 41.114 52.060 1.00 23.24 ? 222 VAL V CA 1 ATOM 5543 C C . VAL D 2 222 ? 49.360 41.555 50.762 1.00 23.04 ? 222 VAL V C 1 ATOM 5544 O O . VAL D 2 222 ? 49.927 41.464 49.667 1.00 23.22 ? 222 VAL V O 1 ATOM 5545 C CB . VAL D 2 222 ? 50.660 42.335 52.764 1.00 22.95 ? 222 VAL V CB 1 ATOM 5546 C CG1 . VAL D 2 222 ? 49.553 43.217 53.282 1.00 22.73 ? 222 VAL V CG1 1 ATOM 5547 C CG2 . VAL D 2 222 ? 51.542 41.893 53.908 1.00 23.16 ? 222 VAL V CG2 1 ATOM 5548 N N . ALA D 2 223 ? 48.116 42.018 50.891 1.00 22.53 ? 223 ALA V N 1 ATOM 5549 C CA . ALA D 2 223 ? 47.375 42.623 49.777 1.00 22.16 ? 223 ALA V CA 1 ATOM 5550 C C . ALA D 2 223 ? 46.386 43.691 50.280 1.00 21.93 ? 223 ALA V C 1 ATOM 5551 O O . ALA D 2 223 ? 45.866 43.584 51.384 1.00 22.02 ? 223 ALA V O 1 ATOM 5552 C CB . ALA D 2 223 ? 46.660 41.547 48.973 1.00 22.08 ? 223 ALA V CB 1 ATOM 5553 N N . THR D 2 224 ? 46.143 44.727 49.486 1.00 21.45 ? 224 THR V N 1 ATOM 5554 C CA . THR D 2 224 ? 45.253 45.799 49.910 1.00 21.46 ? 224 THR V CA 1 ATOM 5555 C C . THR D 2 224 ? 44.528 46.362 48.714 1.00 21.22 ? 224 THR V C 1 ATOM 5556 O O . THR D 2 224 ? 45.130 46.545 47.650 1.00 21.23 ? 224 THR V O 1 ATOM 5557 C CB . THR D 2 224 ? 46.027 46.973 50.529 1.00 21.74 ? 224 THR V CB 1 ATOM 5558 O OG1 . THR D 2 224 ? 47.155 46.482 51.256 1.00 22.85 ? 224 THR V OG1 1 ATOM 5559 C CG2 . THR D 2 224 ? 45.127 47.828 51.446 1.00 21.76 ? 224 THR V CG2 1 ATOM 5560 N N . GLY D 2 225 ? 43.248 46.678 48.912 1.00 20.73 ? 225 GLY V N 1 ATOM 5561 C CA . GLY D 2 225 ? 42.411 47.211 47.855 1.00 19.92 ? 225 GLY V CA 1 ATOM 5562 C C . GLY D 2 225 ? 41.380 48.190 48.354 1.00 19.56 ? 225 GLY V C 1 ATOM 5563 O O . GLY D 2 225 ? 40.424 47.797 49.030 1.00 19.48 ? 225 GLY V O 1 ATOM 5564 N N . LEU D 2 226 ? 41.585 49.467 48.020 1.00 19.18 ? 226 LEU V N 1 ATOM 5565 C CA . LEU D 2 226 ? 40.623 50.520 48.324 1.00 18.61 ? 226 LEU V CA 1 ATOM 5566 C C . LEU D 2 226 ? 39.432 50.278 47.419 1.00 18.40 ? 226 LEU V C 1 ATOM 5567 O O . LEU D 2 226 ? 39.583 49.759 46.303 1.00 18.44 ? 226 LEU V O 1 ATOM 5568 C CB . LEU D 2 226 ? 41.236 51.903 48.095 1.00 18.48 ? 226 LEU V CB 1 ATOM 5569 C CG . LEU D 2 226 ? 40.505 53.248 48.332 1.00 19.28 ? 226 LEU V CG 1 ATOM 5570 C CD1 . LEU D 2 226 ? 39.791 53.736 47.064 1.00 19.97 ? 226 LEU V CD1 1 ATOM 5571 C CD2 . LEU D 2 226 ? 39.564 53.300 49.550 1.00 18.96 ? 226 LEU V CD2 1 ATOM 5572 N N . ASP D 2 227 ? 38.247 50.628 47.910 1.00 17.99 ? 227 ASP V N 1 ATOM 5573 C CA . ASP D 2 227 ? 37.005 50.320 47.205 1.00 17.23 ? 227 ASP V CA 1 ATOM 5574 C C . ASP D 2 227 ? 36.352 51.554 46.586 1.00 16.76 ? 227 ASP V C 1 ATOM 5575 O O . ASP D 2 227 ? 36.546 51.822 45.401 1.00 16.80 ? 227 ASP V O 1 ATOM 5576 C CB . ASP D 2 227 ? 36.024 49.596 48.132 1.00 17.10 ? 227 ASP V CB 1 ATOM 5577 C CG . ASP D 2 227 ? 34.715 49.301 47.463 1.00 16.79 ? 227 ASP V CG 1 ATOM 5578 O OD1 . ASP D 2 227 ? 34.713 48.478 46.527 1.00 16.93 ? 227 ASP V OD1 1 ATOM 5579 O OD2 . ASP D 2 227 ? 33.696 49.902 47.864 1.00 16.81 ? 227 ASP V OD2 1 ATOM 5580 N N . VAL D 2 228 ? 35.595 52.300 47.390 1.00 15.96 ? 228 VAL V N 1 ATOM 5581 C CA . VAL D 2 228 ? 34.772 53.392 46.893 1.00 15.35 ? 228 VAL V CA 1 ATOM 5582 C C . VAL D 2 228 ? 33.383 52.842 46.565 1.00 14.86 ? 228 VAL V C 1 ATOM 5583 O O . VAL D 2 228 ? 32.638 52.430 47.457 1.00 14.20 ? 228 VAL V O 1 ATOM 5584 C CB . VAL D 2 228 ? 35.427 54.107 45.662 1.00 15.32 ? 228 VAL V CB 1 ATOM 5585 C CG1 . VAL D 2 228 ? 34.522 55.151 45.091 1.00 15.33 ? 228 VAL V CG1 1 ATOM 5586 C CG2 . VAL D 2 228 ? 36.745 54.764 46.046 1.00 15.75 ? 228 VAL V CG2 1 ATOM 5587 N N . ARG D 2 232 ? 34.958 48.928 53.141 1.00 2.00 ? 232 ARG V N 1 ATOM 5588 C CA . ARG D 2 232 ? 35.575 49.592 51.997 1.00 2.00 ? 232 ARG V CA 1 ATOM 5589 C C . ARG D 2 232 ? 37.089 49.355 51.846 1.00 2.00 ? 232 ARG V C 1 ATOM 5590 O O . ARG D 2 232 ? 37.600 49.218 50.746 1.00 2.00 ? 232 ARG V O 1 ATOM 5591 C CB . ARG D 2 232 ? 35.224 51.090 51.975 1.00 2.00 ? 232 ARG V CB 1 ATOM 5592 C CG . ARG D 2 232 ? 33.740 51.370 51.651 1.00 2.00 ? 232 ARG V CG 1 ATOM 5593 C CD . ARG D 2 232 ? 33.533 52.662 50.934 1.00 2.00 ? 232 ARG V CD 1 ATOM 5594 N NE . ARG D 2 232 ? 33.706 53.790 51.837 1.00 2.00 ? 232 ARG V NE 1 ATOM 5595 C CZ . ARG D 2 232 ? 34.826 54.499 51.968 1.00 2.00 ? 232 ARG V CZ 1 ATOM 5596 N NH1 . ARG D 2 232 ? 35.900 54.202 51.251 1.00 2.00 ? 232 ARG V NH1 1 ATOM 5597 N NH2 . ARG D 2 232 ? 34.869 55.515 52.816 1.00 2.00 ? 232 ARG V NH2 1 ATOM 5598 N N . SER D 2 233 ? 37.811 49.325 52.953 1.00 3.44 ? 233 SER V N 1 ATOM 5599 C CA . SER D 2 233 ? 39.226 48.943 52.949 1.00 5.14 ? 233 SER V CA 1 ATOM 5600 C C . SER D 2 233 ? 39.321 47.419 53.053 1.00 6.25 ? 233 SER V C 1 ATOM 5601 O O . SER D 2 233 ? 38.740 46.816 53.953 1.00 6.59 ? 233 SER V O 1 ATOM 5602 C CB . SER D 2 233 ? 39.947 49.604 54.129 1.00 5.01 ? 233 SER V CB 1 ATOM 5603 O OG . SER D 2 233 ? 41.298 49.186 54.194 1.00 5.48 ? 233 SER V OG 1 ATOM 5604 N N . TYR D 2 234 ? 40.042 46.781 52.150 1.00 7.65 ? 234 TYR V N 1 ATOM 5605 C CA . TYR D 2 234 ? 39.958 45.329 52.087 1.00 9.40 ? 234 TYR V CA 1 ATOM 5606 C C . TYR D 2 234 ? 41.358 44.718 51.909 1.00 9.87 ? 234 TYR V C 1 ATOM 5607 O O . TYR D 2 234 ? 42.133 45.169 51.065 1.00 10.43 ? 234 TYR V O 1 ATOM 5608 C CB . TYR D 2 234 ? 38.957 44.936 50.980 1.00 9.64 ? 234 TYR V CB 1 ATOM 5609 C CG . TYR D 2 234 ? 38.717 43.452 50.811 1.00 12.46 ? 234 TYR V CG 1 ATOM 5610 C CD1 . TYR D 2 234 ? 37.491 42.868 51.178 1.00 14.78 ? 234 TYR V CD1 1 ATOM 5611 C CD2 . TYR D 2 234 ? 39.719 42.608 50.260 1.00 13.80 ? 234 TYR V CD2 1 ATOM 5612 C CE1 . TYR D 2 234 ? 37.272 41.454 51.005 1.00 14.67 ? 234 TYR V CE1 1 ATOM 5613 C CE2 . TYR D 2 234 ? 39.509 41.220 50.093 1.00 13.11 ? 234 TYR V CE2 1 ATOM 5614 C CZ . TYR D 2 234 ? 38.296 40.657 50.465 1.00 13.40 ? 234 TYR V CZ 1 ATOM 5615 O OH . TYR D 2 234 ? 38.123 39.310 50.290 1.00 13.45 ? 234 TYR V OH 1 ATOM 5616 N N . THR D 2 235 ? 41.703 43.722 52.723 1.00 10.44 ? 235 THR V N 1 ATOM 5617 C CA . THR D 2 235 ? 43.091 43.202 52.724 1.00 11.16 ? 235 THR V CA 1 ATOM 5618 C C . THR D 2 235 ? 43.271 41.708 52.996 1.00 11.20 ? 235 THR V C 1 ATOM 5619 O O . THR D 2 235 ? 42.672 41.130 53.914 1.00 10.96 ? 235 THR V O 1 ATOM 5620 C CB . THR D 2 235 ? 44.039 43.935 53.731 1.00 11.18 ? 235 THR V CB 1 ATOM 5621 O OG1 . THR D 2 235 ? 43.925 43.324 55.025 1.00 11.93 ? 235 THR V OG1 1 ATOM 5622 C CG2 . THR D 2 235 ? 43.761 45.436 53.814 1.00 11.44 ? 235 THR V CG2 1 ATOM 5623 N N . VAL D 2 236 ? 44.169 41.121 52.219 1.00 11.48 ? 236 VAL V N 1 ATOM 5624 C CA . VAL D 2 236 ? 44.433 39.711 52.283 1.00 12.27 ? 236 VAL V CA 1 ATOM 5625 C C . VAL D 2 236 ? 45.894 39.466 52.582 1.00 12.85 ? 236 VAL V C 1 ATOM 5626 O O . VAL D 2 236 ? 46.767 40.099 51.995 1.00 13.14 ? 236 VAL V O 1 ATOM 5627 C CB . VAL D 2 236 ? 44.064 39.023 50.966 1.00 12.30 ? 236 VAL V CB 1 ATOM 5628 C CG1 . VAL D 2 236 ? 44.636 37.620 50.911 1.00 12.33 ? 236 VAL V CG1 1 ATOM 5629 C CG2 . VAL D 2 236 ? 42.552 38.968 50.803 1.00 13.23 ? 236 VAL V CG2 1 ATOM 5630 N N . ARG D 2 237 ? 46.136 38.536 53.504 1.00 13.56 ? 237 ARG V N 1 ATOM 5631 C CA . ARG D 2 237 ? 47.460 38.082 53.862 1.00 14.25 ? 237 ARG V CA 1 ATOM 5632 C C . ARG D 2 237 ? 47.413 36.571 54.009 1.00 15.19 ? 237 ARG V C 1 ATOM 5633 O O . ARG D 2 237 ? 46.425 36.038 54.535 1.00 15.07 ? 237 ARG V O 1 ATOM 5634 C CB . ARG D 2 237 ? 47.869 38.735 55.162 1.00 14.38 ? 237 ARG V CB 1 ATOM 5635 C CG . ARG D 2 237 ? 46.680 39.144 56.034 1.00 14.53 ? 237 ARG V CG 1 ATOM 5636 C CD . ARG D 2 237 ? 47.107 39.858 57.304 1.00 13.83 ? 237 ARG V CD 1 ATOM 5637 N NE . ARG D 2 237 ? 47.711 41.163 57.040 1.00 13.73 ? 237 ARG V NE 1 ATOM 5638 C CZ . ARG D 2 237 ? 48.986 41.359 56.698 1.00 13.75 ? 237 ARG V CZ 1 ATOM 5639 N NH1 . ARG D 2 237 ? 49.826 40.333 56.557 1.00 13.15 ? 237 ARG V NH1 1 ATOM 5640 N NH2 . ARG D 2 237 ? 49.428 42.593 56.503 1.00 13.63 ? 237 ARG V NH2 1 ATOM 5641 N N . GLY D 2 238 ? 48.462 35.890 53.521 1.00 16.40 ? 238 GLY V N 1 ATOM 5642 C CA . GLY D 2 238 ? 48.561 34.408 53.520 1.00 18.11 ? 238 GLY V CA 1 ATOM 5643 C C . GLY D 2 238 ? 49.914 33.876 53.046 1.00 19.38 ? 238 GLY V C 1 ATOM 5644 O O . GLY D 2 238 ? 50.904 34.619 53.028 1.00 19.60 ? 238 GLY V O 1 ATOM 5645 N N . CYS D 2 239 ? 49.967 32.597 52.665 1.00 20.40 ? 239 CYS V N 1 ATOM 5646 C CA . CYS D 2 239 ? 51.222 31.949 52.203 1.00 21.62 ? 239 CYS V CA 1 ATOM 5647 C C . CYS D 2 239 ? 51.312 31.778 50.677 1.00 21.19 ? 239 CYS V C 1 ATOM 5648 O O . CYS D 2 239 ? 50.372 31.290 50.036 1.00 21.58 ? 239 CYS V O 1 ATOM 5649 C CB . CYS D 2 239 ? 51.363 30.560 52.828 1.00 22.18 ? 239 CYS V CB 1 ATOM 5650 S SG . CYS D 2 239 ? 51.263 30.467 54.625 1.00 26.73 ? 239 CYS V SG 1 ATOM 5651 N N . ALA D 2 240 ? 52.451 32.114 50.090 1.00 20.56 ? 240 ALA V N 1 ATOM 5652 C CA . ALA D 2 240 ? 52.511 32.118 48.640 1.00 20.21 ? 240 ALA V CA 1 ATOM 5653 C C . ALA D 2 240 ? 53.717 31.444 48.012 1.00 20.11 ? 240 ALA V C 1 ATOM 5654 O O . ALA D 2 240 ? 54.790 31.315 48.612 1.00 19.96 ? 240 ALA V O 1 ATOM 5655 C CB . ALA D 2 240 ? 52.385 33.537 48.111 1.00 20.34 ? 240 ALA V CB 1 ATOM 5656 N N . THR D 2 241 ? 53.503 31.028 46.770 1.00 19.82 ? 241 THR V N 1 ATOM 5657 C CA . THR D 2 241 ? 54.569 30.696 45.860 1.00 19.46 ? 241 THR V CA 1 ATOM 5658 C C . THR D 2 241 ? 55.093 32.028 45.385 1.00 19.63 ? 241 THR V C 1 ATOM 5659 O O . THR D 2 241 ? 54.355 33.016 45.349 1.00 19.40 ? 241 THR V O 1 ATOM 5660 C CB . THR D 2 241 ? 54.027 29.961 44.647 1.00 19.44 ? 241 THR V CB 1 ATOM 5661 O OG1 . THR D 2 241 ? 52.742 29.416 44.966 1.00 19.00 ? 241 THR V OG1 1 ATOM 5662 C CG2 . THR D 2 241 ? 54.983 28.854 44.202 1.00 18.84 ? 241 THR V CG2 1 ATOM 5663 N N . ALA D 2 242 ? 56.367 32.048 45.010 1.00 19.90 ? 242 ALA V N 1 ATOM 5664 C CA . ALA D 2 242 ? 57.047 33.281 44.639 1.00 19.95 ? 242 ALA V CA 1 ATOM 5665 C C . ALA D 2 242 ? 56.462 33.903 43.385 1.00 20.14 ? 242 ALA V C 1 ATOM 5666 O O . ALA D 2 242 ? 56.597 35.104 43.175 1.00 20.15 ? 242 ALA V O 1 ATOM 5667 C CB . ALA D 2 242 ? 58.520 33.029 44.463 1.00 19.78 ? 242 ALA V CB 1 ATOM 5668 N N . SER D 2 243 ? 55.812 33.085 42.563 1.00 20.58 ? 243 SER V N 1 ATOM 5669 C CA . SER D 2 243 ? 55.304 33.540 41.280 1.00 21.04 ? 243 SER V CA 1 ATOM 5670 C C . SER D 2 243 ? 53.808 33.685 41.340 1.00 21.51 ? 243 SER V C 1 ATOM 5671 O O . SER D 2 243 ? 53.177 33.988 40.342 1.00 21.21 ? 243 SER V O 1 ATOM 5672 C CB . SER D 2 243 ? 55.677 32.564 40.184 1.00 20.91 ? 243 SER V CB 1 ATOM 5673 O OG . SER D 2 243 ? 55.122 31.313 40.501 1.00 21.01 ? 243 SER V OG 1 ATOM 5674 N N . TRP D 2 244 ? 53.237 33.458 42.514 1.00 22.59 ? 244 TRP V N 1 ATOM 5675 C CA . TRP D 2 244 ? 51.867 33.887 42.756 1.00 23.65 ? 244 TRP V CA 1 ATOM 5676 C C . TRP D 2 244 ? 51.894 35.291 43.296 1.00 24.55 ? 244 TRP V C 1 ATOM 5677 O O . TRP D 2 244 ? 50.858 35.837 43.639 1.00 24.71 ? 244 TRP V O 1 ATOM 5678 C CB . TRP D 2 244 ? 51.142 32.974 43.737 1.00 23.58 ? 244 TRP V CB 1 ATOM 5679 C CG . TRP D 2 244 ? 49.646 32.969 43.539 1.00 23.44 ? 244 TRP V CG 1 ATOM 5680 C CD1 . TRP D 2 244 ? 48.913 32.201 42.645 1.00 23.49 ? 244 TRP V CD1 1 ATOM 5681 C CD2 . TRP D 2 244 ? 48.703 33.757 44.242 1.00 22.37 ? 244 TRP V CD2 1 ATOM 5682 N NE1 . TRP D 2 244 ? 47.569 32.481 42.759 1.00 21.70 ? 244 TRP V NE1 1 ATOM 5683 C CE2 . TRP D 2 244 ? 47.413 33.430 43.734 1.00 22.55 ? 244 TRP V CE2 1 ATOM 5684 C CE3 . TRP D 2 244 ? 48.814 34.708 45.254 1.00 22.47 ? 244 TRP V CE3 1 ATOM 5685 C CZ2 . TRP D 2 244 ? 46.254 34.019 44.215 1.00 23.80 ? 244 TRP V CZ2 1 ATOM 5686 C CZ3 . TRP D 2 244 ? 47.662 35.305 45.731 1.00 24.35 ? 244 TRP V CZ3 1 ATOM 5687 C CH2 . TRP D 2 244 ? 46.394 34.956 45.215 1.00 25.69 ? 244 TRP V CH2 1 ATOM 5688 N N . CYS D 2 245 ? 53.095 35.864 43.360 1.00 25.93 ? 245 CYS V N 1 ATOM 5689 C CA . CYS D 2 245 ? 53.311 37.234 43.828 1.00 27.48 ? 245 CYS V CA 1 ATOM 5690 C C . CYS D 2 245 ? 53.402 38.248 42.666 1.00 27.27 ? 245 CYS V C 1 ATOM 5691 O O . CYS D 2 245 ? 53.422 39.454 42.901 1.00 27.75 ? 245 CYS V O 1 ATOM 5692 C CB . CYS D 2 245 ? 54.568 37.325 44.731 1.00 28.19 ? 245 CYS V CB 1 ATOM 5693 S SG . CYS D 2 245 ? 54.570 36.427 46.403 1.00 33.19 ? 245 CYS V SG 1 ATOM 5694 N N . GLN D 2 246 ? 53.465 37.781 41.417 1.00 27.18 ? 246 GLN V N 1 ATOM 5695 C CA . GLN D 2 246 ? 53.442 38.714 40.268 1.00 26.87 ? 246 GLN V CA 1 ATOM 5696 C C . GLN D 2 246 ? 52.579 38.349 39.060 1.00 26.79 ? 246 GLN V C 1 ATOM 5697 O O . GLN D 2 246 ? 52.200 37.197 38.866 1.00 26.76 ? 246 GLN V O 1 ATOM 5698 C CB . GLN D 2 246 ? 54.838 39.110 39.809 1.00 26.67 ? 246 GLN V CB 1 ATOM 5699 C CG . GLN D 2 246 ? 55.923 38.234 40.284 1.00 26.17 ? 246 GLN V CG 1 ATOM 5700 C CD . GLN D 2 246 ? 56.933 39.040 41.037 1.00 26.52 ? 246 GLN V CD 1 ATOM 5701 O OE1 . GLN D 2 246 ? 58.132 38.854 40.869 1.00 27.80 ? 246 GLN V OE1 1 ATOM 5702 N NE2 . GLN D 2 246 ? 56.456 39.969 41.863 1.00 25.87 ? 246 GLN V NE2 1 ATOM 5703 N N . GLY D 2 247 ? 52.294 39.354 38.238 1.00 26.50 ? 247 GLY V N 1 ATOM 5704 C CA . GLY D 2 247 ? 51.267 39.231 37.231 1.00 26.37 ? 247 GLY V CA 1 ATOM 5705 C C . GLY D 2 247 ? 49.943 39.362 37.947 1.00 26.44 ? 247 GLY V C 1 ATOM 5706 O O . GLY D 2 247 ? 49.894 39.838 39.084 1.00 26.53 ? 247 GLY V O 1 ATOM 5707 N N . SER D 2 248 ? 48.875 38.913 37.293 1.00 26.49 ? 248 SER V N 1 ATOM 5708 C CA . SER D 2 248 ? 47.511 39.088 37.792 1.00 26.59 ? 248 SER V CA 1 ATOM 5709 C C . SER D 2 248 ? 47.236 38.354 39.109 1.00 26.44 ? 248 SER V C 1 ATOM 5710 O O . SER D 2 248 ? 47.038 38.986 40.140 1.00 26.76 ? 248 SER V O 1 ATOM 5711 C CB . SER D 2 248 ? 46.507 38.665 36.719 1.00 26.83 ? 248 SER V CB 1 ATOM 5712 O OG . SER D 2 248 ? 45.189 39.013 37.099 1.00 27.73 ? 248 SER V OG 1 ATOM 5713 N N . HIS D 2 249 ? 47.240 37.025 39.059 1.00 26.17 ? 249 HIS V N 1 ATOM 5714 C CA . HIS D 2 249 ? 46.915 36.156 40.194 1.00 25.82 ? 249 HIS V CA 1 ATOM 5715 C C . HIS D 2 249 ? 46.166 36.802 41.342 1.00 26.11 ? 249 HIS V C 1 ATOM 5716 O O . HIS D 2 249 ? 44.934 36.820 41.402 1.00 25.87 ? 249 HIS V O 1 ATOM 5717 C CB . HIS D 2 249 ? 48.185 35.539 40.750 1.00 25.49 ? 249 HIS V CB 1 ATOM 5718 C CG . HIS D 2 249 ? 48.754 34.471 39.886 1.00 24.46 ? 249 HIS V CG 1 ATOM 5719 N ND1 . HIS D 2 249 ? 50.000 34.567 39.312 1.00 24.26 ? 249 HIS V ND1 1 ATOM 5720 C CD2 . HIS D 2 249 ? 48.245 33.284 39.489 1.00 23.63 ? 249 HIS V CD2 1 ATOM 5721 C CE1 . HIS D 2 249 ? 50.241 33.480 38.601 1.00 23.56 ? 249 HIS V CE1 1 ATOM 5722 N NE2 . HIS D 2 249 ? 49.190 32.687 38.690 1.00 23.61 ? 249 HIS V NE2 1 ATOM 5723 N N . VAL D 2 250 ? 46.942 37.330 42.269 1.00 26.63 ? 250 VAL V N 1 ATOM 5724 C CA . VAL D 2 250 ? 46.383 37.875 43.475 1.00 27.25 ? 250 VAL V CA 1 ATOM 5725 C C . VAL D 2 250 ? 45.270 38.851 43.133 1.00 27.67 ? 250 VAL V C 1 ATOM 5726 O O . VAL D 2 250 ? 44.184 38.752 43.689 1.00 27.93 ? 250 VAL V O 1 ATOM 5727 C CB . VAL D 2 250 ? 47.481 38.473 44.383 1.00 27.14 ? 250 VAL V CB 1 ATOM 5728 C CG1 . VAL D 2 250 ? 48.608 39.071 43.539 1.00 27.37 ? 250 VAL V CG1 1 ATOM 5729 C CG2 . VAL D 2 250 ? 46.887 39.456 45.384 1.00 27.13 ? 250 VAL V CG2 1 ATOM 5730 N N . ALA D 2 251 ? 45.531 39.752 42.184 1.00 28.18 ? 251 ALA V N 1 ATOM 5731 C CA . ALA D 2 251 ? 44.563 40.774 41.780 1.00 28.51 ? 251 ALA V CA 1 ATOM 5732 C C . ALA D 2 251 ? 43.160 40.195 41.700 1.00 28.96 ? 251 ALA V C 1 ATOM 5733 O O . ALA D 2 251 ? 42.297 40.518 42.511 1.00 28.98 ? 251 ALA V O 1 ATOM 5734 C CB . ALA D 2 251 ? 44.963 41.394 40.461 1.00 28.37 ? 251 ALA V CB 1 ATOM 5735 N N . ASP D 2 252 ? 42.949 39.304 40.746 1.00 29.57 ? 252 ASP V N 1 ATOM 5736 C CA . ASP D 2 252 ? 41.664 38.664 40.582 1.00 30.46 ? 252 ASP V CA 1 ATOM 5737 C C . ASP D 2 252 ? 41.516 37.521 41.584 1.00 31.51 ? 252 ASP V C 1 ATOM 5738 O O . ASP D 2 252 ? 41.054 36.423 41.233 1.00 31.76 ? 252 ASP V O 1 ATOM 5739 C CB . ASP D 2 252 ? 41.579 38.121 39.182 1.00 30.33 ? 252 ASP V CB 1 ATOM 5740 C CG . ASP D 2 252 ? 42.816 37.377 38.808 1.00 29.95 ? 252 ASP V CG 1 ATOM 5741 O OD1 . ASP D 2 252 ? 42.697 36.178 38.493 1.00 30.33 ? 252 ASP V OD1 1 ATOM 5742 O OD2 . ASP D 2 252 ? 43.909 37.982 38.886 1.00 28.97 ? 252 ASP V OD2 1 ATOM 5743 N N . SER D 2 253 ? 41.929 37.784 42.822 1.00 32.35 ? 253 SER V N 1 ATOM 5744 C CA . SER D 2 253 ? 41.639 36.920 43.944 1.00 33.15 ? 253 SER V CA 1 ATOM 5745 C C . SER D 2 253 ? 40.231 37.248 44.462 1.00 33.65 ? 253 SER V C 1 ATOM 5746 O O . SER D 2 253 ? 39.578 36.390 45.051 1.00 34.02 ? 253 SER V O 1 ATOM 5747 C CB . SER D 2 253 ? 42.681 37.151 45.033 1.00 33.36 ? 253 SER V CB 1 ATOM 5748 O OG . SER D 2 253 ? 42.831 36.045 45.901 1.00 34.34 ? 253 SER V OG 1 ATOM 5749 N N . PHE D 2 254 ? 39.761 38.474 44.216 1.00 34.09 ? 254 PHE V N 1 ATOM 5750 C CA . PHE D 2 254 ? 38.442 38.949 44.670 1.00 34.76 ? 254 PHE V CA 1 ATOM 5751 C C . PHE D 2 254 ? 37.784 39.830 43.595 1.00 35.57 ? 254 PHE V C 1 ATOM 5752 O O . PHE D 2 254 ? 38.245 39.822 42.448 1.00 35.67 ? 254 PHE V O 1 ATOM 5753 C CB . PHE D 2 254 ? 38.628 39.731 45.953 1.00 34.66 ? 254 PHE V CB 1 ATOM 5754 C CG . PHE D 2 254 ? 40.049 40.144 46.201 1.00 35.06 ? 254 PHE V CG 1 ATOM 5755 C CD1 . PHE D 2 254 ? 40.786 40.787 45.222 1.00 34.52 ? 254 PHE V CD1 1 ATOM 5756 C CD2 . PHE D 2 254 ? 40.662 39.874 47.423 1.00 36.35 ? 254 PHE V CD2 1 ATOM 5757 C CE1 . PHE D 2 254 ? 42.113 41.156 45.459 1.00 35.13 ? 254 PHE V CE1 1 ATOM 5758 C CE2 . PHE D 2 254 ? 41.995 40.252 47.670 1.00 36.12 ? 254 PHE V CE2 1 ATOM 5759 C CZ . PHE D 2 254 ? 42.717 40.892 46.686 1.00 35.13 ? 254 PHE V CZ 1 ATOM 5760 N N . PRO D 2 255 ? 36.684 40.564 43.935 1.00 36.35 ? 255 PRO V N 1 ATOM 5761 C CA . PRO D 2 255 ? 36.076 41.652 43.073 1.00 36.68 ? 255 PRO V CA 1 ATOM 5762 C C . PRO D 2 255 ? 37.002 42.818 42.620 1.00 36.98 ? 255 PRO V C 1 ATOM 5763 O O . PRO D 2 255 ? 38.026 43.076 43.257 1.00 36.93 ? 255 PRO V O 1 ATOM 5764 C CB . PRO D 2 255 ? 34.927 42.188 43.935 1.00 36.39 ? 255 PRO V CB 1 ATOM 5765 C CG . PRO D 2 255 ? 34.506 41.012 44.746 1.00 36.56 ? 255 PRO V CG 1 ATOM 5766 C CD . PRO D 2 255 ? 35.732 40.116 44.974 1.00 36.26 ? 255 PRO V CD 1 ATOM 5767 N N . THR D 2 256 ? 36.616 43.517 41.546 1.00 37.39 ? 256 THR V N 1 ATOM 5768 C CA . THR D 2 256 ? 37.514 44.446 40.804 1.00 38.03 ? 256 THR V CA 1 ATOM 5769 C C . THR D 2 256 ? 38.125 45.616 41.610 1.00 38.84 ? 256 THR V C 1 ATOM 5770 O O . THR D 2 256 ? 37.472 46.151 42.509 1.00 38.84 ? 256 THR V O 1 ATOM 5771 C CB . THR D 2 256 ? 36.858 44.969 39.468 1.00 37.88 ? 256 THR V CB 1 ATOM 5772 O OG1 . THR D 2 256 ? 37.620 46.065 38.936 1.00 36.88 ? 256 THR V OG1 1 ATOM 5773 C CG2 . THR D 2 256 ? 35.396 45.400 39.679 1.00 37.41 ? 256 THR V CG2 1 ATOM 5774 N N . HIS D 2 257 ? 39.363 46.010 41.268 1.00 39.70 ? 257 HIS V N 1 ATOM 5775 C CA . HIS D 2 257 ? 40.123 47.032 42.026 1.00 40.48 ? 257 HIS V CA 1 ATOM 5776 C C . HIS D 2 257 ? 41.151 47.883 41.276 1.00 41.08 ? 257 HIS V C 1 ATOM 5777 O O . HIS D 2 257 ? 41.531 47.557 40.154 1.00 41.17 ? 257 HIS V O 1 ATOM 5778 C CB . HIS D 2 257 ? 40.797 46.396 43.221 1.00 40.33 ? 257 HIS V CB 1 ATOM 5779 C CG . HIS D 2 257 ? 39.867 46.181 44.363 1.00 41.23 ? 257 HIS V CG 1 ATOM 5780 N ND1 . HIS D 2 257 ? 39.535 47.186 45.246 1.00 42.53 ? 257 HIS V ND1 1 ATOM 5781 C CD2 . HIS D 2 257 ? 39.167 45.089 44.747 1.00 41.80 ? 257 HIS V CD2 1 ATOM 5782 C CE1 . HIS D 2 257 ? 38.683 46.714 46.140 1.00 43.04 ? 257 HIS V CE1 1 ATOM 5783 N NE2 . HIS D 2 257 ? 38.440 45.445 45.856 1.00 42.77 ? 257 HIS V NE2 1 ATOM 5784 N N . LEU D 2 258 ? 41.598 48.970 41.929 1.00 41.92 ? 258 LEU V N 1 ATOM 5785 C CA . LEU D 2 258 ? 42.469 49.997 41.303 1.00 42.33 ? 258 LEU V CA 1 ATOM 5786 C C . LEU D 2 258 ? 43.934 49.893 41.744 1.00 42.49 ? 258 LEU V C 1 ATOM 5787 O O . LEU D 2 258 ? 44.248 50.077 42.918 1.00 42.09 ? 258 LEU V O 1 ATOM 5788 C CB . LEU D 2 258 ? 41.912 51.435 41.480 1.00 42.16 ? 258 LEU V CB 1 ATOM 5789 C CG . LEU D 2 258 ? 40.572 51.779 40.792 1.00 41.88 ? 258 LEU V CG 1 ATOM 5790 C CD1 . LEU D 2 258 ? 40.040 53.171 41.147 1.00 41.18 ? 258 LEU V CD1 1 ATOM 5791 C CD2 . LEU D 2 258 ? 40.671 51.593 39.272 1.00 42.19 ? 258 LEU V CD2 1 ATOM 5792 N N . ASN D 2 259 ? 44.801 49.649 40.753 1.00 42.99 ? 259 ASN V N 1 ATOM 5793 C CA . ASN D 2 259 ? 46.205 49.242 40.920 1.00 43.60 ? 259 ASN V CA 1 ATOM 5794 C C . ASN D 2 259 ? 46.637 48.951 42.365 1.00 42.28 ? 259 ASN V C 1 ATOM 5795 O O . ASN D 2 259 ? 47.711 49.363 42.820 1.00 42.14 ? 259 ASN V O 1 ATOM 5796 C CB . ASN D 2 259 ? 47.178 50.157 40.129 1.00 44.82 ? 259 ASN V CB 1 ATOM 5797 C CG . ASN D 2 259 ? 47.256 51.591 40.670 1.00 50.14 ? 259 ASN V CG 1 ATOM 5798 O OD1 . ASN D 2 259 ? 46.642 51.932 41.690 1.00 51.09 ? 259 ASN V OD1 1 ATOM 5799 N ND2 . ASN D 2 259 ? 48.035 52.438 39.966 1.00 58.92 ? 259 ASN V ND2 1 ATOM 5800 N N . VAL D 2 260 ? 45.765 48.217 43.060 1.00 40.84 ? 260 VAL V N 1 ATOM 5801 C CA . VAL D 2 260 ? 45.964 47.808 44.447 1.00 39.32 ? 260 VAL V CA 1 ATOM 5802 C C . VAL D 2 260 ? 47.023 46.713 44.497 1.00 38.37 ? 260 VAL V C 1 ATOM 5803 O O . VAL D 2 260 ? 47.135 45.902 43.581 1.00 38.20 ? 260 VAL V O 1 ATOM 5804 C CB . VAL D 2 260 ? 44.647 47.346 45.108 1.00 39.36 ? 260 VAL V CB 1 ATOM 5805 C CG1 . VAL D 2 260 ? 43.532 48.400 44.919 1.00 38.76 ? 260 VAL V CG1 1 ATOM 5806 C CG2 . VAL D 2 260 ? 44.225 45.965 44.592 1.00 39.13 ? 260 VAL V CG2 1 ATOM 5807 N N . SER D 2 261 ? 47.800 46.689 45.567 1.00 37.09 ? 261 SER V N 1 ATOM 5808 C CA . SER D 2 261 ? 49.104 46.082 45.469 1.00 36.11 ? 261 SER V CA 1 ATOM 5809 C C . SER D 2 261 ? 49.359 44.992 46.455 1.00 35.33 ? 261 SER V C 1 ATOM 5810 O O . SER D 2 261 ? 48.595 44.771 47.384 1.00 35.19 ? 261 SER V O 1 ATOM 5811 C CB . SER D 2 261 ? 50.179 47.139 45.629 1.00 36.39 ? 261 SER V CB 1 ATOM 5812 O OG . SER D 2 261 ? 50.166 47.629 46.954 1.00 37.23 ? 261 SER V OG 1 ATOM 5813 N N . VAL D 2 262 ? 50.494 44.351 46.242 1.00 34.57 ? 262 VAL V N 1 ATOM 5814 C CA . VAL D 2 262 ? 50.835 43.111 46.868 1.00 33.92 ? 262 VAL V CA 1 ATOM 5815 C C . VAL D 2 262 ? 52.247 43.217 47.372 1.00 34.07 ? 262 VAL V C 1 ATOM 5816 O O . VAL D 2 262 ? 53.149 43.588 46.626 1.00 34.11 ? 262 VAL V O 1 ATOM 5817 C CB . VAL D 2 262 ? 50.746 41.955 45.843 1.00 33.77 ? 262 VAL V CB 1 ATOM 5818 C CG1 . VAL D 2 262 ? 49.323 41.736 45.447 1.00 33.26 ? 262 VAL V CG1 1 ATOM 5819 C CG2 . VAL D 2 262 ? 51.583 42.235 44.590 1.00 32.97 ? 262 VAL V CG2 1 ATOM 5820 N N . SER D 2 263 ? 52.448 42.900 48.640 1.00 34.37 ? 263 SER V N 1 ATOM 5821 C CA . SER D 2 263 ? 53.808 42.834 49.172 1.00 34.79 ? 263 SER V CA 1 ATOM 5822 C C . SER D 2 263 ? 54.232 41.385 49.464 1.00 34.92 ? 263 SER V C 1 ATOM 5823 O O . SER D 2 263 ? 53.566 40.672 50.215 1.00 34.90 ? 263 SER V O 1 ATOM 5824 C CB . SER D 2 263 ? 53.971 43.734 50.398 1.00 34.78 ? 263 SER V CB 1 ATOM 5825 O OG . SER D 2 263 ? 55.341 43.992 50.645 1.00 34.69 ? 263 SER V OG 1 ATOM 5826 N N . CYS D 2 264 ? 55.337 40.969 48.845 1.00 35.08 ? 264 CYS V N 1 ATOM 5827 C CA . CYS D 2 264 ? 55.847 39.603 48.927 1.00 35.21 ? 264 CYS V CA 1 ATOM 5828 C C . CYS D 2 264 ? 57.243 39.637 49.507 1.00 35.33 ? 264 CYS V C 1 ATOM 5829 O O . CYS D 2 264 ? 58.177 40.157 48.888 1.00 35.48 ? 264 CYS V O 1 ATOM 5830 C CB . CYS D 2 264 ? 55.899 38.976 47.529 1.00 35.34 ? 264 CYS V CB 1 ATOM 5831 S SG . CYS D 2 264 ? 56.229 37.161 47.422 1.00 36.02 ? 264 CYS V SG 1 ATOM 5832 N N . CYS D 2 265 ? 57.380 39.086 50.703 1.00 35.42 ? 265 CYS V N 1 ATOM 5833 C CA . CYS D 2 265 ? 58.662 39.006 51.364 1.00 35.62 ? 265 CYS V CA 1 ATOM 5834 C C . CYS D 2 265 ? 59.204 37.596 51.189 1.00 35.55 ? 265 CYS V C 1 ATOM 5835 O O . CYS D 2 265 ? 58.530 36.720 50.628 1.00 36.01 ? 265 CYS V O 1 ATOM 5836 C CB . CYS D 2 265 ? 58.470 39.250 52.854 1.00 35.60 ? 265 CYS V CB 1 ATOM 5837 S SG . CYS D 2 265 ? 58.094 37.705 53.755 1.00 37.11 ? 265 CYS V SG 1 ATOM 5838 N N . HIS D 2 266 ? 60.420 37.377 51.674 1.00 35.24 ? 266 HIS V N 1 ATOM 5839 C CA . HIS D 2 266 ? 60.794 36.050 52.141 1.00 34.93 ? 266 HIS V CA 1 ATOM 5840 C C . HIS D 2 266 ? 61.342 36.186 53.563 1.00 34.65 ? 266 HIS V C 1 ATOM 5841 O O . HIS D 2 266 ? 62.101 37.116 53.860 1.00 34.75 ? 266 HIS V O 1 ATOM 5842 C CB . HIS D 2 266 ? 61.771 35.344 51.195 1.00 35.01 ? 266 HIS V CB 1 ATOM 5843 C CG . HIS D 2 266 ? 61.972 33.893 51.517 1.00 34.53 ? 266 HIS V CG 1 ATOM 5844 N ND1 . HIS D 2 266 ? 63.170 33.241 51.306 1.00 34.15 ? 266 HIS V ND1 1 ATOM 5845 C CD2 . HIS D 2 266 ? 61.135 32.977 52.058 1.00 33.62 ? 266 HIS V CD2 1 ATOM 5846 C CE1 . HIS D 2 266 ? 63.055 31.982 51.689 1.00 34.06 ? 266 HIS V CE1 1 ATOM 5847 N NE2 . HIS D 2 266 ? 61.831 31.797 52.151 1.00 34.07 ? 266 HIS V NE2 1 ATOM 5848 N N . GLY D 2 267 ? 60.927 35.276 54.440 1.00 34.03 ? 267 GLY V N 1 ATOM 5849 C CA . GLY D 2 267 ? 61.282 35.349 55.850 1.00 33.00 ? 267 GLY V CA 1 ATOM 5850 C C . GLY D 2 267 ? 60.046 35.079 56.668 1.00 32.34 ? 267 GLY V C 1 ATOM 5851 O O . GLY D 2 267 ? 59.075 35.834 56.605 1.00 32.17 ? 267 GLY V O 1 ATOM 5852 N N . SER D 2 268 ? 60.090 33.989 57.424 1.00 31.61 ? 268 SER V N 1 ATOM 5853 C CA . SER D 2 268 ? 58.946 33.514 58.189 1.00 31.06 ? 268 SER V CA 1 ATOM 5854 C C . SER D 2 268 ? 58.356 34.550 59.139 1.00 30.80 ? 268 SER V C 1 ATOM 5855 O O . SER D 2 268 ? 59.076 35.226 59.854 1.00 31.12 ? 268 SER V O 1 ATOM 5856 C CB . SER D 2 268 ? 59.344 32.272 58.974 1.00 30.99 ? 268 SER V CB 1 ATOM 5857 O OG . SER D 2 268 ? 58.201 31.674 59.547 1.00 30.82 ? 268 SER V OG 1 ATOM 5858 N N . GLY D 2 269 ? 57.039 34.669 59.144 1.00 30.60 ? 269 GLY V N 1 ATOM 5859 C CA . GLY D 2 269 ? 56.356 35.586 60.041 1.00 30.79 ? 269 GLY V CA 1 ATOM 5860 C C . GLY D 2 269 ? 56.488 37.024 59.600 1.00 31.26 ? 269 GLY V C 1 ATOM 5861 O O . GLY D 2 269 ? 55.898 37.917 60.203 1.00 31.28 ? 269 GLY V O 1 ATOM 5862 N N . CYS D 2 270 ? 57.254 37.244 58.533 1.00 31.77 ? 270 CYS V N 1 ATOM 5863 C CA . CYS D 2 270 ? 57.610 38.587 58.060 1.00 32.41 ? 270 CYS V CA 1 ATOM 5864 C C . CYS D 2 270 ? 56.410 39.518 57.931 1.00 31.94 ? 270 CYS V C 1 ATOM 5865 O O . CYS D 2 270 ? 56.480 40.670 58.332 1.00 32.10 ? 270 CYS V O 1 ATOM 5866 C CB . CYS D 2 270 ? 58.288 38.501 56.697 1.00 32.72 ? 270 CYS V CB 1 ATOM 5867 S SG . CYS D 2 270 ? 57.051 38.318 55.380 1.00 35.99 ? 270 CYS V SG 1 ATOM 5868 N N . ASN D 2 271 ? 55.319 39.014 57.360 1.00 31.65 ? 271 ASN V N 1 ATOM 5869 C CA . ASN D 2 271 ? 54.162 39.837 57.025 1.00 31.51 ? 271 ASN V CA 1 ATOM 5870 C C . ASN D 2 271 ? 53.303 40.179 58.240 1.00 31.74 ? 271 ASN V C 1 ATOM 5871 O O . ASN D 2 271 ? 52.072 40.146 58.190 1.00 31.97 ? 271 ASN V O 1 ATOM 5872 C CB . ASN D 2 271 ? 53.332 39.199 55.897 1.00 31.32 ? 271 ASN V CB 1 ATOM 5873 C CG . ASN D 2 271 ? 52.797 37.826 56.252 1.00 30.32 ? 271 ASN V CG 1 ATOM 5874 O OD1 . ASN D 2 271 ? 52.792 37.417 57.405 1.00 30.11 ? 271 ASN V OD1 1 ATOM 5875 N ND2 . ASN D 2 271 ? 52.340 37.110 55.251 1.00 29.54 ? 271 ASN V ND2 1 ATOM 5876 N N . SER D 2 272 ? 53.978 40.505 59.334 1.00 31.76 ? 272 SER V N 1 ATOM 5877 C CA . SER D 2 272 ? 53.333 41.015 60.528 1.00 31.61 ? 272 SER V CA 1 ATOM 5878 C C . SER D 2 272 ? 52.672 42.352 60.202 1.00 31.58 ? 272 SER V C 1 ATOM 5879 O O . SER D 2 272 ? 53.263 43.196 59.524 1.00 31.33 ? 272 SER V O 1 ATOM 5880 C CB . SER D 2 272 ? 54.359 41.192 61.654 1.00 31.66 ? 272 SER V CB 1 ATOM 5881 O OG . SER D 2 272 ? 55.456 40.296 61.515 1.00 31.34 ? 272 SER V OG 1 ATOM 5882 N N . PRO D 2 273 ? 51.430 42.531 60.657 1.00 31.73 ? 273 PRO V N 1 ATOM 5883 C CA . PRO D 2 273 ? 50.724 43.802 60.565 1.00 32.37 ? 273 PRO V CA 1 ATOM 5884 C C . PRO D 2 273 ? 51.358 44.928 61.420 1.00 33.27 ? 273 PRO V C 1 ATOM 5885 O O . PRO D 2 273 ? 51.280 46.111 61.038 1.00 33.18 ? 273 PRO V O 1 ATOM 5886 C CB . PRO D 2 273 ? 49.320 43.446 61.058 1.00 32.16 ? 273 PRO V CB 1 ATOM 5887 C CG . PRO D 2 273 ? 49.199 41.993 60.834 1.00 31.53 ? 273 PRO V CG 1 ATOM 5888 C CD . PRO D 2 273 ? 50.544 41.447 61.105 1.00 31.57 ? 273 PRO V CD 1 ATOM 5889 N N . THR D 2 274 ? 51.957 44.551 62.562 1.00 34.27 ? 274 THR V N 1 ATOM 5890 C CA . THR D 2 274 ? 52.883 45.400 63.371 1.00 35.30 ? 274 THR V CA 1 ATOM 5891 C C . THR D 2 274 ? 52.419 46.786 63.873 1.00 35.35 ? 274 THR V C 1 ATOM 5892 O O . THR D 2 274 ? 52.040 47.696 63.115 1.00 35.50 ? 274 THR V O 1 ATOM 5893 C CB . THR D 2 274 ? 54.287 45.556 62.694 1.00 35.61 ? 274 THR V CB 1 ATOM 5894 O OG1 . THR D 2 274 ? 54.156 45.527 61.261 1.00 37.09 ? 274 THR V OG1 1 ATOM 5895 C CG2 . THR D 2 274 ? 55.199 44.438 63.117 1.00 35.80 ? 274 THR V CG2 1 HETATM 5896 C C1 . NAG E 3 . ? 11.180 7.427 4.776 1.00 60.14 ? 1052 NAG U C1 1 HETATM 5897 C C2 . NAG E 3 . ? 10.890 7.404 3.251 1.00 65.66 ? 1052 NAG U C2 1 HETATM 5898 C C3 . NAG E 3 . ? 9.591 8.121 2.873 1.00 66.05 ? 1052 NAG U C3 1 HETATM 5899 C C4 . NAG E 3 . ? 8.452 7.756 3.806 1.00 67.79 ? 1052 NAG U C4 1 HETATM 5900 C C5 . NAG E 3 . ? 8.976 8.278 5.147 1.00 66.59 ? 1052 NAG U C5 1 HETATM 5901 C C6 . NAG E 3 . ? 7.974 8.481 6.281 1.00 66.86 ? 1052 NAG U C6 1 HETATM 5902 C C7 . NAG E 3 . ? 12.247 7.757 1.200 1.00 66.99 ? 1052 NAG U C7 1 HETATM 5903 C C8 . NAG E 3 . ? 13.405 8.509 0.603 1.00 65.90 ? 1052 NAG U C8 1 HETATM 5904 N N2 . NAG E 3 . ? 11.970 8.020 2.481 1.00 66.89 ? 1052 NAG U N2 1 HETATM 5905 O O3 . NAG E 3 . ? 9.284 7.817 1.543 1.00 66.48 ? 1052 NAG U O3 1 HETATM 5906 O O4 . NAG E 3 . ? 7.309 8.421 3.321 1.00 72.52 ? 1052 NAG U O4 1 HETATM 5907 O O5 . NAG E 3 . ? 9.984 7.363 5.545 1.00 63.93 ? 1052 NAG U O5 1 HETATM 5908 O O6 . NAG E 3 . ? 8.134 7.441 7.224 1.00 67.00 ? 1052 NAG U O6 1 HETATM 5909 O O7 . NAG E 3 . ? 11.601 6.953 0.525 1.00 67.64 ? 1052 NAG U O7 1 HETATM 5910 C C1 . NAG F 3 . ? 6.852 9.877 3.749 1.00 78.23 ? 1053 NAG U C1 1 HETATM 5911 C C2 . NAG F 3 . ? 6.561 9.817 2.218 1.00 80.87 ? 1053 NAG U C2 1 HETATM 5912 C C3 . NAG F 3 . ? 5.128 10.375 1.984 1.00 81.45 ? 1053 NAG U C3 1 HETATM 5913 C C4 . NAG F 3 . ? 4.062 9.775 2.917 1.00 81.24 ? 1053 NAG U C4 1 HETATM 5914 C C5 . NAG F 3 . ? 4.555 9.698 4.374 1.00 81.50 ? 1053 NAG U C5 1 HETATM 5915 C C6 . NAG F 3 . ? 3.572 8.921 5.253 1.00 80.74 ? 1053 NAG U C6 1 HETATM 5916 C C7 . NAG F 3 . ? 8.175 10.104 0.263 1.00 82.86 ? 1053 NAG U C7 1 HETATM 5917 C C8 . NAG F 3 . ? 9.149 11.060 -0.374 1.00 82.01 ? 1053 NAG U C8 1 HETATM 5918 N N2 . NAG F 3 . ? 7.553 10.535 1.389 1.00 82.63 ? 1053 NAG U N2 1 HETATM 5919 O O3 . NAG F 3 . ? 4.681 10.220 0.649 1.00 81.98 ? 1053 NAG U O3 1 HETATM 5920 O O4 . NAG F 3 . ? 2.881 10.548 2.843 1.00 80.59 ? 1053 NAG U O4 1 HETATM 5921 O O5 . NAG F 3 . ? 5.868 9.130 4.459 1.00 80.60 ? 1053 NAG U O5 1 HETATM 5922 O O6 . NAG F 3 . ? 3.853 9.213 6.601 1.00 79.85 ? 1053 NAG U O6 1 HETATM 5923 O O7 . NAG F 3 . ? 8.008 8.993 -0.255 1.00 83.20 ? 1053 NAG U O7 1 HETATM 5924 C C1 . NAG G 3 . ? 48.313 -3.783 12.353 1.00 70.47 ? 1160 NAG U C1 1 HETATM 5925 C C2 . NAG G 3 . ? 48.774 -5.254 12.510 1.00 76.53 ? 1160 NAG U C2 1 HETATM 5926 C C3 . NAG G 3 . ? 48.557 -5.780 13.943 1.00 77.23 ? 1160 NAG U C3 1 HETATM 5927 C C4 . NAG G 3 . ? 49.352 -4.860 14.877 1.00 77.60 ? 1160 NAG U C4 1 HETATM 5928 C C5 . NAG G 3 . ? 48.728 -3.453 14.801 1.00 77.07 ? 1160 NAG U C5 1 HETATM 5929 C C6 . NAG G 3 . ? 49.489 -2.469 15.698 1.00 77.73 ? 1160 NAG U C6 1 HETATM 5930 C C7 . NAG G 3 . ? 48.675 -6.361 10.319 1.00 79.76 ? 1160 NAG U C7 1 HETATM 5931 C C8 . NAG G 3 . ? 47.895 -7.290 9.415 1.00 79.52 ? 1160 NAG U C8 1 HETATM 5932 N N2 . NAG G 3 . ? 48.141 -6.125 11.523 1.00 77.91 ? 1160 NAG U N2 1 HETATM 5933 O O3 . NAG G 3 . ? 48.902 -7.155 14.080 1.00 77.22 ? 1160 NAG U O3 1 HETATM 5934 O O4 . NAG G 3 . ? 49.383 -5.346 16.206 1.00 78.23 ? 1160 NAG U O4 1 HETATM 5935 O O5 . NAG G 3 . ? 48.684 -2.935 13.457 1.00 74.74 ? 1160 NAG U O5 1 HETATM 5936 O O6 . NAG G 3 . ? 48.601 -1.953 16.667 1.00 78.39 ? 1160 NAG U O6 1 HETATM 5937 O O7 . NAG G 3 . ? 49.747 -5.853 9.952 1.00 80.71 ? 1160 NAG U O7 1 HETATM 5938 C C1 . NAG H 3 . ? 13.856 -10.006 -5.921 1.00 61.00 ? 1170 NAG U C1 1 HETATM 5939 C C2 . NAG H 3 . ? 13.807 -10.590 -7.344 1.00 66.11 ? 1170 NAG U C2 1 HETATM 5940 C C3 . NAG H 3 . ? 12.371 -10.683 -7.938 1.00 66.87 ? 1170 NAG U C3 1 HETATM 5941 C C4 . NAG H 3 . ? 11.275 -11.042 -6.920 1.00 67.60 ? 1170 NAG U C4 1 HETATM 5942 C C5 . NAG H 3 . ? 11.543 -10.420 -5.543 1.00 67.26 ? 1170 NAG U C5 1 HETATM 5943 C C6 . NAG H 3 . ? 10.664 -11.074 -4.485 1.00 69.13 ? 1170 NAG U C6 1 HETATM 5944 C C7 . NAG H 3 . ? 16.038 -9.844 -8.193 1.00 67.45 ? 1170 NAG U C7 1 HETATM 5945 C C8 . NAG H 3 . ? 16.762 -9.093 -9.279 1.00 67.23 ? 1170 NAG U C8 1 HETATM 5946 N N2 . NAG H 3 . ? 14.698 -9.894 -8.276 1.00 67.06 ? 1170 NAG U N2 1 HETATM 5947 O O3 . NAG H 3 . ? 12.307 -11.652 -8.971 1.00 66.25 ? 1170 NAG U O3 1 HETATM 5948 O O4 . NAG H 3 . ? 9.998 -10.677 -7.417 1.00 67.36 ? 1170 NAG U O4 1 HETATM 5949 O O5 . NAG H 3 . ? 12.884 -10.684 -5.156 1.00 64.81 ? 1170 NAG U O5 1 HETATM 5950 O O6 . NAG H 3 . ? 11.316 -10.978 -3.226 1.00 71.10 ? 1170 NAG U O6 1 HETATM 5951 O O7 . NAG H 3 . ? 16.689 -10.363 -7.287 1.00 67.34 ? 1170 NAG U O7 1 HETATM 5952 C C1 . NAG I 3 . ? 31.434 20.733 6.942 1.00 69.60 ? 1259 NAG U C1 1 HETATM 5953 C C2 . NAG I 3 . ? 32.576 21.376 6.118 1.00 75.87 ? 1259 NAG U C2 1 HETATM 5954 C C3 . NAG I 3 . ? 32.287 22.836 5.774 1.00 77.02 ? 1259 NAG U C3 1 HETATM 5955 C C4 . NAG I 3 . ? 30.922 22.869 5.095 1.00 77.53 ? 1259 NAG U C4 1 HETATM 5956 C C5 . NAG I 3 . ? 29.878 22.553 6.179 1.00 76.34 ? 1259 NAG U C5 1 HETATM 5957 C C6 . NAG I 3 . ? 28.467 22.523 5.587 1.00 76.30 ? 1259 NAG U C6 1 HETATM 5958 C C7 . NAG I 3 . ? 35.018 20.865 6.186 1.00 78.34 ? 1259 NAG U C7 1 HETATM 5959 C C8 . NAG I 3 . ? 34.968 20.337 4.768 1.00 77.60 ? 1259 NAG U C8 1 HETATM 5960 N N2 . NAG I 3 . ? 33.887 21.322 6.768 1.00 77.10 ? 1259 NAG U N2 1 HETATM 5961 O O3 . NAG I 3 . ? 33.302 23.369 4.943 1.00 78.10 ? 1259 NAG U O3 1 HETATM 5962 O O4 . NAG I 3 . ? 30.688 24.119 4.468 1.00 78.58 ? 1259 NAG U O4 1 HETATM 5963 O O5 . NAG I 3 . ? 30.128 21.330 6.882 1.00 73.41 ? 1259 NAG U O5 1 HETATM 5964 O O6 . NAG I 3 . ? 27.851 23.737 5.954 1.00 76.02 ? 1259 NAG U O6 1 HETATM 5965 O O7 . NAG I 3 . ? 36.099 20.867 6.789 1.00 78.87 ? 1259 NAG U O7 1 HETATM 5966 C C1 . NAG J 3 . ? 47.606 39.301 22.140 1.00 59.72 ? 1052 NAG V C1 1 HETATM 5967 C C2 . NAG J 3 . ? 48.922 39.910 21.665 1.00 65.32 ? 1052 NAG V C2 1 HETATM 5968 C C3 . NAG J 3 . ? 48.644 41.127 20.781 1.00 67.00 ? 1052 NAG V C3 1 HETATM 5969 C C4 . NAG J 3 . ? 47.905 40.554 19.571 1.00 68.66 ? 1052 NAG V C4 1 HETATM 5970 C C5 . NAG J 3 . ? 46.578 39.967 20.056 1.00 66.40 ? 1052 NAG V C5 1 HETATM 5971 C C6 . NAG J 3 . ? 45.751 39.350 18.936 1.00 65.77 ? 1052 NAG V C6 1 HETATM 5972 C C7 . NAG J 3 . ? 51.112 39.691 22.744 1.00 66.41 ? 1052 NAG V C7 1 HETATM 5973 C C8 . NAG J 3 . ? 51.623 38.945 21.541 1.00 66.56 ? 1052 NAG V C8 1 HETATM 5974 N N2 . NAG J 3 . ? 49.844 40.140 22.768 1.00 66.00 ? 1052 NAG V N2 1 HETATM 5975 O O3 . NAG J 3 . ? 49.848 41.771 20.411 1.00 67.05 ? 1052 NAG V O3 1 HETATM 5976 O O4 . NAG J 3 . ? 47.729 41.501 18.542 1.00 73.88 ? 1052 NAG V O4 1 HETATM 5977 O O5 . NAG J 3 . ? 46.842 38.935 21.002 1.00 63.36 ? 1052 NAG V O5 1 HETATM 5978 O O6 . NAG J 3 . ? 46.488 38.301 18.354 1.00 64.31 ? 1052 NAG V O6 1 HETATM 5979 O O7 . NAG J 3 . ? 51.888 39.858 23.675 1.00 66.65 ? 1052 NAG V O7 1 HETATM 5980 C C1 . NAG K 3 . ? 48.576 41.388 17.181 1.00 78.73 ? 1053 NAG V C1 1 HETATM 5981 C C2 . NAG K 3 . ? 47.502 42.195 16.438 1.00 80.62 ? 1053 NAG V C2 1 HETATM 5982 C C3 . NAG K 3 . ? 48.204 43.146 15.449 1.00 82.27 ? 1053 NAG V C3 1 HETATM 5983 C C4 . NAG K 3 . ? 49.322 43.965 16.139 1.00 83.09 ? 1053 NAG V C4 1 HETATM 5984 C C5 . NAG K 3 . ? 50.145 43.153 17.159 1.00 81.78 ? 1053 NAG V C5 1 HETATM 5985 C C6 . NAG K 3 . ? 51.005 44.047 18.041 1.00 81.16 ? 1053 NAG V C6 1 HETATM 5986 C C7 . NAG K 3 . ? 45.154 41.508 15.914 1.00 79.49 ? 1053 NAG V C7 1 HETATM 5987 C C8 . NAG K 3 . ? 44.600 42.714 16.632 1.00 79.47 ? 1053 NAG V C8 1 HETATM 5988 N N2 . NAG K 3 . ? 46.486 41.320 15.843 1.00 80.08 ? 1053 NAG V N2 1 HETATM 5989 O O3 . NAG K 3 . ? 47.275 44.019 14.835 1.00 82.51 ? 1053 NAG V O3 1 HETATM 5990 O O4 . NAG K 3 . ? 50.210 44.495 15.166 1.00 84.90 ? 1053 NAG V O4 1 HETATM 5991 O O5 . NAG K 3 . ? 49.327 42.309 17.961 1.00 80.30 ? 1053 NAG V O5 1 HETATM 5992 O O6 . NAG K 3 . ? 52.347 43.899 17.637 1.00 80.71 ? 1053 NAG V O6 1 HETATM 5993 O O7 . NAG K 3 . ? 44.364 40.723 15.398 1.00 78.42 ? 1053 NAG V O7 1 HETATM 5994 C C1 . NAG L 3 . ? 58.221 21.798 30.526 1.00 58.07 ? 1170 NAG V C1 1 HETATM 5995 C C2 . NAG L 3 . ? 59.435 22.594 30.052 1.00 62.67 ? 1170 NAG V C2 1 HETATM 5996 C C3 . NAG L 3 . ? 60.532 22.648 31.113 1.00 63.38 ? 1170 NAG V C3 1 HETATM 5997 C C4 . NAG L 3 . ? 59.986 23.033 32.496 1.00 63.68 ? 1170 NAG V C4 1 HETATM 5998 C C5 . NAG L 3 . ? 58.834 22.093 32.881 1.00 63.22 ? 1170 NAG V C5 1 HETATM 5999 C C6 . NAG L 3 . ? 58.250 22.423 34.271 1.00 63.25 ? 1170 NAG V C6 1 HETATM 6000 C C7 . NAG L 3 . ? 59.960 22.650 27.647 1.00 65.44 ? 1170 NAG V C7 1 HETATM 6001 C C8 . NAG L 3 . ? 60.537 21.883 26.488 1.00 64.49 ? 1170 NAG V C8 1 HETATM 6002 N N2 . NAG L 3 . ? 59.958 22.012 28.827 1.00 64.50 ? 1170 NAG V N2 1 HETATM 6003 O O3 . NAG L 3 . ? 61.486 23.591 30.685 1.00 64.47 ? 1170 NAG V O3 1 HETATM 6004 O O4 . NAG L 3 . ? 61.015 23.003 33.466 1.00 64.65 ? 1170 NAG V O4 1 HETATM 6005 O O5 . NAG L 3 . ? 57.839 22.172 31.854 1.00 61.41 ? 1170 NAG V O5 1 HETATM 6006 O O6 . NAG L 3 . ? 57.377 21.416 34.756 1.00 62.45 ? 1170 NAG V O6 1 HETATM 6007 O O7 . NAG L 3 . ? 59.522 23.797 27.486 1.00 65.71 ? 1170 NAG V O7 1 HETATM 6008 C C1 . NAG M 3 . ? 40.724 28.427 60.613 1.00 62.06 ? 1160 NAG V C1 1 HETATM 6009 C C2 . NAG M 3 . ? 39.573 29.424 60.956 1.00 68.26 ? 1160 NAG V C2 1 HETATM 6010 C C3 . NAG M 3 . ? 38.377 28.604 61.445 1.00 67.79 ? 1160 NAG V C3 1 HETATM 6011 C C4 . NAG M 3 . ? 37.933 27.757 60.251 1.00 68.09 ? 1160 NAG V C4 1 HETATM 6012 C C5 . NAG M 3 . ? 39.102 26.835 59.834 1.00 66.63 ? 1160 NAG V C5 1 HETATM 6013 C C6 . NAG M 3 . ? 38.727 25.887 58.694 1.00 65.98 ? 1160 NAG V C6 1 HETATM 6014 C C7 . NAG M 3 . ? 39.358 31.712 62.044 1.00 73.48 ? 1160 NAG V C7 1 HETATM 6015 C C8 . NAG M 3 . ? 38.291 32.208 61.089 1.00 72.96 ? 1160 NAG V C8 1 HETATM 6016 N N2 . NAG M 3 . ? 39.891 30.471 61.932 1.00 71.46 ? 1160 NAG V N2 1 HETATM 6017 O O3 . NAG M 3 . ? 37.348 29.413 61.987 1.00 67.20 ? 1160 NAG V O3 1 HETATM 6018 O O4 . NAG M 3 . ? 36.780 27.022 60.602 1.00 70.38 ? 1160 NAG V O4 1 HETATM 6019 O O5 . NAG M 3 . ? 40.278 27.596 59.523 1.00 64.80 ? 1160 NAG V O5 1 HETATM 6020 O O6 . NAG M 3 . ? 38.098 24.741 59.232 1.00 63.65 ? 1160 NAG V O6 1 HETATM 6021 O O7 . NAG M 3 . ? 39.746 32.470 62.940 1.00 74.54 ? 1160 NAG V O7 1 HETATM 6022 C C1 . NAG N 3 . ? 48.317 53.838 40.237 1.00 71.21 ? 1259 NAG V C1 1 HETATM 6023 C C2 . NAG N 3 . ? 47.700 53.581 41.638 1.00 78.81 ? 1259 NAG V C2 1 HETATM 6024 C C3 . NAG N 3 . ? 48.414 54.478 42.682 1.00 78.60 ? 1259 NAG V C3 1 HETATM 6025 C C4 . NAG N 3 . ? 49.919 54.143 42.691 1.00 78.17 ? 1259 NAG V C4 1 HETATM 6026 C C5 . NAG N 3 . ? 50.535 54.148 41.249 1.00 77.34 ? 1259 NAG V C5 1 HETATM 6027 C C6 . NAG N 3 . ? 51.949 53.547 41.121 1.00 78.36 ? 1259 NAG V C6 1 HETATM 6028 C C7 . NAG N 3 . ? 45.345 53.061 42.475 1.00 85.40 ? 1259 NAG V C7 1 HETATM 6029 C C8 . NAG N 3 . ? 45.849 52.012 43.447 1.00 85.27 ? 1259 NAG V C8 1 HETATM 6030 N N2 . NAG N 3 . ? 46.233 53.729 41.681 1.00 82.81 ? 1259 NAG V N2 1 HETATM 6031 O O3 . NAG N 3 . ? 47.848 54.393 43.987 1.00 78.10 ? 1259 NAG V O3 1 HETATM 6032 O O4 . NAG N 3 . ? 50.578 55.023 43.590 1.00 77.28 ? 1259 NAG V O4 1 HETATM 6033 O O5 . NAG N 3 . ? 49.718 53.526 40.237 1.00 73.72 ? 1259 NAG V O5 1 HETATM 6034 O O6 . NAG N 3 . ? 52.190 52.447 41.989 1.00 79.97 ? 1259 NAG V O6 1 HETATM 6035 O O7 . NAG N 3 . ? 44.116 53.280 42.427 1.00 85.86 ? 1259 NAG V O7 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 GLY 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 VAL 3 3 ? ? ? A . n A 1 4 LEU 4 4 ? ? ? A . n A 1 5 GLY 5 5 ? ? ? A . n A 1 6 ALA 6 6 ? ? ? A . n A 1 7 PRO 7 7 ? ? ? A . n A 1 8 ASP 8 8 ? ? ? A . n A 1 9 GLU 9 9 9 GLU GLU A . n A 1 10 SER 10 10 10 SER SER A . n A 1 11 ASN 11 11 11 ASN ASN A . n A 1 12 CYS 12 12 12 CYS CYS A . n A 1 13 GLY 13 13 13 GLY GLY A . n A 1 14 CYS 14 14 14 CYS CYS A . n A 1 15 GLN 15 15 15 GLN GLN A . n A 1 16 ASN 16 16 16 ASN ASN A . n A 1 17 GLY 17 17 17 GLY GLY A . n A 1 18 GLY 18 18 18 GLY GLY A . n A 1 19 VAL 19 19 19 VAL VAL A . n A 1 20 CYS 20 20 20 CYS CYS A . n A 1 21 VAL 21 21 21 VAL VAL A . n A 1 22 SER 22 22 22 SER SER A . n A 1 23 TYR 23 23 23 TYR TYR A . n A 1 24 LYS 24 24 24 LYS LYS A . n A 1 25 TYR 25 25 25 TYR TYR A . n A 1 26 PHE 26 26 26 PHE PHE A . n A 1 27 SER 27 27 27 SER SER A . n A 1 28 ARG 28 28 28 ARG ARG A . n A 1 29 ILE 29 29 29 ILE ILE A . n A 1 30 ARG 30 30 30 ARG ARG A . n A 1 31 ARG 31 31 31 ARG ARG A . n A 1 32 CYS 32 32 32 CYS CYS A . n A 1 33 SER 33 33 33 SER SER A . n A 1 34 CYS 34 34 34 CYS CYS A . n A 1 35 PRO 35 35 35 PRO PRO A . n A 1 36 ARG 36 36 36 ARG ARG A . n A 1 37 LYS 37 37 37 LYS LYS A . n A 1 38 PHE 38 38 38 PHE PHE A . n A 1 39 GLN 39 39 39 GLN GLN A . n A 1 40 GLY 40 40 40 GLY GLY A . n A 1 41 GLU 41 41 41 GLU GLU A . n A 1 42 HIS 42 42 42 HIS HIS A . n A 1 43 CYS 43 43 43 CYS CYS A . n A 1 44 GLU 44 44 44 GLU GLU A . n A 1 45 ILE 45 45 45 ILE ILE A . n A 1 46 ASP 46 46 46 ASP ASP A . n A 1 47 ALA 47 47 47 ALA ALA A . n A 1 48 SER 48 48 48 SER SER A . n A 1 49 LYS 49 49 49 LYS LYS A . n A 1 50 THR 50 50 50 THR THR A . n A 1 51 CYS 51 51 51 CYS CYS A . n A 1 52 TYR 52 52 52 TYR TYR A . n A 1 53 HIS 53 53 53 HIS HIS A . n A 1 54 GLY 54 54 54 GLY GLY A . n A 1 55 ASN 55 55 55 ASN ASN A . n A 1 56 GLY 56 56 56 GLY GLY A . n A 1 57 ASP 57 57 57 ASP ASP A . n A 1 58 SER 58 58 58 SER SER A . n A 1 59 TYR 59 59 59 TYR TYR A . n A 1 60 ARG 60 60 60 ARG ARG A . n A 1 61 GLY 61 61 61 GLY GLY A . n A 1 62 LYS 62 62 62 LYS LYS A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 ASN 64 64 64 ASN ASN A . n A 1 65 THR 65 65 65 THR THR A . n A 1 66 ASP 66 66 66 ASP ASP A . n A 1 67 THR 67 67 67 THR THR A . n A 1 68 LYS 68 68 68 LYS LYS A . n A 1 69 GLY 69 69 69 GLY GLY A . n A 1 70 ARG 70 70 70 ARG ARG A . n A 1 71 PRO 71 71 71 PRO PRO A . n A 1 72 CYS 72 72 72 CYS CYS A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 ALA 74 74 74 ALA ALA A . n A 1 75 TRP 75 75 75 TRP TRP A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 PRO 78 78 78 PRO PRO A . n A 1 79 ALA 79 79 79 ALA ALA A . n A 1 80 VAL 80 80 80 VAL VAL A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 GLN 82 82 82 GLN GLN A . n A 1 83 LYS 83 83 83 LYS LYS A . n A 1 84 PRO 84 84 84 PRO PRO A . n A 1 85 TYR 85 85 85 TYR TYR A . n A 1 86 ASN 86 86 86 ASN ASN A . n A 1 87 ALA 87 87 87 ALA ALA A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 ARG 89 89 89 ARG ARG A . n A 1 90 PRO 90 90 90 PRO PRO A . n A 1 91 ASP 91 91 91 ASP ASP A . n A 1 92 ALA 92 92 92 ALA ALA A . n A 1 93 ILE 93 93 93 ILE ILE A . n A 1 94 SER 94 94 94 SER SER A . n A 1 95 LEU 95 95 95 LEU LEU A . n A 1 96 GLY 96 96 96 GLY GLY A . n A 1 97 LEU 97 97 97 LEU LEU A . n A 1 98 GLY 98 98 98 GLY GLY A . n A 1 99 LYS 99 99 99 LYS LYS A . n A 1 100 HIS 100 100 100 HIS HIS A . n A 1 101 ASN 101 101 101 ASN ASN A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 CYS 103 103 103 CYS CYS A . n A 1 104 ARG 104 104 104 ARG ARG A . n A 1 105 ASN 105 105 105 ASN ASN A . n A 1 106 PRO 106 106 106 PRO PRO A . n A 1 107 ASP 107 107 107 ASP ASP A . n A 1 108 ASN 108 108 108 ASN ASN A . n A 1 109 GLN 109 109 109 GLN GLN A . n A 1 110 LYS 110 110 110 LYS LYS A . n A 1 111 ARG 111 111 111 ARG ARG A . n A 1 112 PRO 112 112 112 PRO PRO A . n A 1 113 TRP 113 113 113 TRP TRP A . n A 1 114 CYS 114 114 114 CYS CYS A . n A 1 115 TYR 115 115 115 TYR TYR A . n A 1 116 VAL 116 116 116 VAL VAL A . n A 1 117 GLN 117 117 117 GLN GLN A . n A 1 118 ILE 118 118 118 ILE ILE A . n A 1 119 GLY 119 119 119 GLY GLY A . n A 1 120 LEU 120 120 120 LEU LEU A . n A 1 121 ARG 121 121 121 ARG ARG A . n A 1 122 GLN 122 122 122 GLN GLN A . n A 1 123 PHE 123 123 123 PHE PHE A . n A 1 124 VAL 124 124 124 VAL VAL A . n A 1 125 GLN 125 125 125 GLN GLN A . n A 1 126 GLU 126 126 126 GLU GLU A . n A 1 127 CYS 127 127 127 CYS CYS A . n A 1 128 MET 128 128 128 MET MET A . n A 1 129 VAL 129 129 129 VAL VAL A . n A 1 130 HIS 130 130 130 HIS HIS A . n A 1 131 ASP 131 131 131 ASP ASP A . n A 1 132 CYS 132 132 132 CYS CYS A . n A 1 133 SER 133 133 ? ? ? A . n A 1 134 LEU 134 134 ? ? ? A . n B 2 1 LEU 1 1 1 LEU LEU U . n B 2 2 GLN 2 2 2 GLN GLN U . n B 2 3 CYS 3 3 3 CYS CYS U . n B 2 4 MET 4 4 4 MET MET U . n B 2 5 GLN 5 5 5 GLN GLN U . n B 2 6 CYS 6 6 6 CYS CYS U . n B 2 7 GLU 7 7 7 GLU GLU U . n B 2 8 SER 8 8 8 SER SER U . n B 2 9 ASN 9 9 9 ASN ASN U . n B 2 10 GLN 10 10 10 GLN GLN U . n B 2 11 SER 11 11 11 SER SER U . n B 2 12 CYS 12 12 12 CYS CYS U . n B 2 13 LEU 13 13 13 LEU LEU U . n B 2 14 VAL 14 14 14 VAL VAL U . n B 2 15 GLU 15 15 15 GLU GLU U . n B 2 16 GLU 16 16 16 GLU GLU U . n B 2 17 CYS 17 17 17 CYS CYS U . n B 2 18 ALA 18 18 18 ALA ALA U . n B 2 19 LEU 19 19 19 LEU LEU U . n B 2 20 GLY 20 20 20 GLY GLY U . n B 2 21 GLN 21 21 21 GLN GLN U . n B 2 22 ASP 22 22 22 ASP ASP U . n B 2 23 LEU 23 23 23 LEU LEU U . n B 2 24 CYS 24 24 24 CYS CYS U . n B 2 25 ARG 25 25 25 ARG ARG U . n B 2 26 THR 26 26 26 THR THR U . n B 2 27 THR 27 27 27 THR THR U . n B 2 28 VAL 28 28 28 VAL VAL U . n B 2 29 LEU 29 29 29 LEU LEU U . n B 2 30 ARG 30 30 30 ARG ARG U . n B 2 31 GLU 31 31 31 GLU GLU U . n B 2 32 TRP 32 32 32 TRP TRP U . n B 2 33 GLN 33 33 33 GLN GLN U . n B 2 34 ASP 34 34 34 ASP ASP U . n B 2 35 ASP 35 35 35 ASP ASP U . n B 2 36 ARG 36 36 36 ARG ARG U . n B 2 37 GLU 37 37 37 GLU GLU U . n B 2 38 LEU 38 38 38 LEU LEU U . n B 2 39 GLU 39 39 39 GLU GLU U . n B 2 40 VAL 40 40 40 VAL VAL U . n B 2 41 VAL 41 41 41 VAL VAL U . n B 2 42 THR 42 42 42 THR THR U . n B 2 43 ARG 43 43 43 ARG ARG U . n B 2 44 GLY 44 44 44 GLY GLY U . n B 2 45 CYS 45 45 45 CYS CYS U . n B 2 46 ALA 46 46 46 ALA ALA U . n B 2 47 HIS 47 47 47 HIS HIS U . n B 2 48 SER 48 48 48 SER SER U . n B 2 49 GLU 49 49 49 GLU GLU U . n B 2 50 LYS 50 50 50 LYS LYS U . n B 2 51 THR 51 51 51 THR THR U . n B 2 52 ASN 52 52 52 ASN ASN U . n B 2 53 ARG 53 53 53 ARG ARG U . n B 2 54 THR 54 54 54 THR THR U . n B 2 55 MET 55 55 55 MET MET U . n B 2 56 SER 56 56 56 SER SER U . n B 2 57 TYR 57 57 57 TYR TYR U . n B 2 58 ARG 58 58 58 ARG ARG U . n B 2 59 MET 59 59 59 MET MET U . n B 2 60 GLY 60 60 60 GLY GLY U . n B 2 61 SER 61 61 61 SER SER U . n B 2 62 MET 62 62 62 MET MET U . n B 2 63 ILE 63 63 63 ILE ILE U . n B 2 64 ILE 64 64 64 ILE ILE U . n B 2 65 SER 65 65 65 SER SER U . n B 2 66 LEU 66 66 66 LEU LEU U . n B 2 67 THR 67 67 67 THR THR U . n B 2 68 GLU 68 68 68 GLU GLU U . n B 2 69 THR 69 69 69 THR THR U . n B 2 70 VAL 70 70 70 VAL VAL U . n B 2 71 CYS 71 71 71 CYS CYS U . n B 2 72 ALA 72 72 72 ALA ALA U . n B 2 73 THR 73 73 73 THR THR U . n B 2 74 ASN 74 74 74 ASN ASN U . n B 2 75 LEU 75 75 75 LEU LEU U . n B 2 76 CYS 76 76 76 CYS CYS U . n B 2 77 ASN 77 77 77 ASN ASN U . n B 2 78 ARG 78 78 78 ARG ARG U . n B 2 79 PRO 79 79 79 PRO PRO U . n B 2 80 ARG 80 80 80 ARG ARG U . n B 2 81 PRO 81 81 81 PRO PRO U . n B 2 82 GLY 82 82 ? ? ? U . n B 2 83 ALA 83 83 ? ? ? U . n B 2 84 ARG 84 84 ? ? ? U . n B 2 85 GLY 85 85 ? ? ? U . n B 2 86 ARG 86 86 ? ? ? U . n B 2 87 ALA 87 87 ? ? ? U . n B 2 88 PHE 88 88 ? ? ? U . n B 2 89 PRO 89 89 ? ? ? U . n B 2 90 GLN 90 90 ? ? ? U . n B 2 91 GLY 91 91 ? ? ? U . n B 2 92 ARG 92 92 ? ? ? U . n B 2 93 TYR 93 93 93 TYR TYR U . n B 2 94 LEU 94 94 94 LEU LEU U . n B 2 95 GLU 95 95 95 GLU GLU U . n B 2 96 CYS 96 96 96 CYS CYS U . n B 2 97 ALA 97 97 97 ALA ALA U . n B 2 98 SER 98 98 98 SER SER U . n B 2 99 CYS 99 99 99 CYS CYS U . n B 2 100 THR 100 100 100 THR THR U . n B 2 101 SER 101 101 101 SER SER U . n B 2 102 LEU 102 102 102 LEU LEU U . n B 2 103 ASP 103 103 103 ASP ASP U . n B 2 104 GLN 104 104 104 GLN GLN U . n B 2 105 SER 105 105 105 SER SER U . n B 2 106 CYS 106 106 106 CYS CYS U . n B 2 107 GLU 107 107 107 GLU GLU U . n B 2 108 ARG 108 108 108 ARG ARG U . n B 2 109 GLY 109 109 109 GLY GLY U . n B 2 110 ARG 110 110 110 ARG ARG U . n B 2 111 GLU 111 111 111 GLU GLU U . n B 2 112 GLN 112 112 112 GLN GLN U . n B 2 113 SER 113 113 113 SER SER U . n B 2 114 LEU 114 114 114 LEU LEU U . n B 2 115 GLN 115 115 115 GLN GLN U . n B 2 116 CYS 116 116 116 CYS CYS U . n B 2 117 ARG 117 117 117 ARG ARG U . n B 2 118 TYR 118 118 118 TYR TYR U . n B 2 119 PRO 119 119 119 PRO PRO U . n B 2 120 THR 120 120 120 THR THR U . n B 2 121 GLU 121 121 121 GLU GLU U . n B 2 122 HIS 122 122 122 HIS HIS U . n B 2 123 CYS 123 123 123 CYS CYS U . n B 2 124 ILE 124 124 124 ILE ILE U . n B 2 125 GLU 125 125 125 GLU GLU U . n B 2 126 VAL 126 126 126 VAL VAL U . n B 2 127 VAL 127 127 127 VAL VAL U . n B 2 128 THR 128 128 128 THR THR U . n B 2 129 LEU 129 129 129 LEU LEU U . n B 2 130 GLN 130 130 130 GLN GLN U . n B 2 131 SER 131 131 131 SER SER U . n B 2 132 THR 132 132 132 THR THR U . n B 2 133 GLU 133 133 133 GLU GLU U . n B 2 134 ARG 134 134 134 ARG ARG U . n B 2 135 SER 135 135 135 SER SER U . n B 2 136 LEU 136 136 136 LEU LEU U . n B 2 137 LYS 137 137 137 LYS LYS U . n B 2 138 ASP 138 138 138 ASP ASP U . n B 2 139 GLU 139 139 139 GLU GLU U . n B 2 140 ASP 140 140 140 ASP ASP U . n B 2 141 TYR 141 141 141 TYR TYR U . n B 2 142 THR 142 142 142 THR THR U . n B 2 143 ARG 143 143 143 ARG ARG U . n B 2 144 GLY 144 144 144 GLY GLY U . n B 2 145 CYS 145 145 145 CYS CYS U . n B 2 146 GLY 146 146 146 GLY GLY U . n B 2 147 SER 147 147 147 SER SER U . n B 2 148 LEU 148 148 148 LEU LEU U . n B 2 149 PRO 149 149 149 PRO PRO U . n B 2 150 GLY 150 150 150 GLY GLY U . n B 2 151 CYS 151 151 151 CYS CYS U . n B 2 152 PRO 152 152 152 PRO PRO U . n B 2 153 GLY 153 153 153 GLY GLY U . n B 2 154 THR 154 154 154 THR THR U . n B 2 155 ALA 155 155 155 ALA ALA U . n B 2 156 GLY 156 156 156 GLY GLY U . n B 2 157 PHE 157 157 157 PHE PHE U . n B 2 158 HIS 158 158 158 HIS HIS U . n B 2 159 SER 159 159 159 SER SER U . n B 2 160 ASN 160 160 160 ASN ASN U . n B 2 161 GLN 161 161 161 GLN GLN U . n B 2 162 THR 162 162 162 THR THR U . n B 2 163 PHE 163 163 163 PHE PHE U . n B 2 164 HIS 164 164 164 HIS HIS U . n B 2 165 PHE 165 165 165 PHE PHE U . n B 2 166 LEU 166 166 166 LEU LEU U . n B 2 167 LYS 167 167 167 LYS LYS U . n B 2 168 CYS 168 168 168 CYS CYS U . n B 2 169 CYS 169 169 169 CYS CYS U . n B 2 170 ASN 170 170 170 ASN ASN U . n B 2 171 TYR 171 171 171 TYR TYR U . n B 2 172 THR 172 172 172 THR THR U . n B 2 173 HIS 173 173 173 HIS HIS U . n B 2 174 CYS 174 174 174 CYS CYS U . n B 2 175 ASN 175 175 175 ASN ASN U . n B 2 176 GLY 176 176 176 GLY GLY U . n B 2 177 GLY 177 177 177 GLY GLY U . n B 2 178 PRO 178 178 178 PRO PRO U . n B 2 179 VAL 179 179 179 VAL VAL U . n B 2 180 LEU 180 180 180 LEU LEU U . n B 2 181 ASP 181 181 181 ASP ASP U . n B 2 182 LEU 182 182 182 LEU LEU U . n B 2 183 GLN 183 183 183 GLN GLN U . n B 2 184 SER 184 184 184 SER SER U . n B 2 185 PHE 185 185 185 PHE PHE U . n B 2 186 PRO 186 186 186 PRO PRO U . n B 2 187 PRO 187 187 187 PRO PRO U . n B 2 188 ASN 188 188 188 ASN ASN U . n B 2 189 GLY 189 189 189 GLY GLY U . n B 2 190 PHE 190 190 190 PHE PHE U . n B 2 191 GLN 191 191 191 GLN GLN U . n B 2 192 CYS 192 192 192 CYS CYS U . n B 2 193 TYR 193 193 193 TYR TYR U . n B 2 194 SER 194 194 194 SER SER U . n B 2 195 CYS 195 195 195 CYS CYS U . n B 2 196 GLU 196 196 196 GLU GLU U . n B 2 197 GLY 197 197 197 GLY GLY U . n B 2 198 ASN 198 198 198 ASN ASN U . n B 2 199 ASN 199 199 199 ASN ASN U . n B 2 200 THR 200 200 200 THR THR U . n B 2 201 LEU 201 201 201 LEU LEU U . n B 2 202 GLY 202 202 202 GLY GLY U . n B 2 203 CYS 203 203 203 CYS CYS U . n B 2 204 SER 204 204 204 SER SER U . n B 2 205 SER 205 205 205 SER SER U . n B 2 206 GLU 206 206 206 GLU GLU U . n B 2 207 GLU 207 207 207 GLU GLU U . n B 2 208 ALA 208 208 208 ALA ALA U . n B 2 209 SER 209 209 209 SER SER U . n B 2 210 LEU 210 210 210 LEU LEU U . n B 2 211 ILE 211 211 211 ILE ILE U . n B 2 212 ASN 212 212 212 ASN ASN U . n B 2 213 CYS 213 213 213 CYS CYS U . n B 2 214 ARG 214 214 214 ARG ARG U . n B 2 215 GLY 215 215 215 GLY GLY U . n B 2 216 PRO 216 216 216 PRO PRO U . n B 2 217 MET 217 217 217 MET MET U . n B 2 218 ASN 218 218 218 ASN ASN U . n B 2 219 GLN 219 219 219 GLN GLN U . n B 2 220 CYS 220 220 220 CYS CYS U . n B 2 221 LEU 221 221 221 LEU LEU U . n B 2 222 VAL 222 222 222 VAL VAL U . n B 2 223 ALA 223 223 223 ALA ALA U . n B 2 224 THR 224 224 224 THR THR U . n B 2 225 GLY 225 225 225 GLY GLY U . n B 2 226 LEU 226 226 226 LEU LEU U . n B 2 227 ASP 227 227 ? ? ? U . n B 2 228 VAL 228 228 ? ? ? U . n B 2 229 LEU 229 229 ? ? ? U . n B 2 230 GLY 230 230 ? ? ? U . n B 2 231 ASN 231 231 ? ? ? U . n B 2 232 ARG 232 232 232 ARG ARG U . n B 2 233 SER 233 233 233 SER SER U . n B 2 234 TYR 234 234 234 TYR TYR U . n B 2 235 THR 235 235 235 THR THR U . n B 2 236 VAL 236 236 236 VAL VAL U . n B 2 237 ARG 237 237 237 ARG ARG U . n B 2 238 GLY 238 238 238 GLY GLY U . n B 2 239 CYS 239 239 239 CYS CYS U . n B 2 240 ALA 240 240 240 ALA ALA U . n B 2 241 THR 241 241 241 THR THR U . n B 2 242 ALA 242 242 242 ALA ALA U . n B 2 243 SER 243 243 243 SER SER U . n B 2 244 TRP 244 244 244 TRP TRP U . n B 2 245 CYS 245 245 245 CYS CYS U . n B 2 246 GLN 246 246 246 GLN GLN U . n B 2 247 GLY 247 247 247 GLY GLY U . n B 2 248 SER 248 248 248 SER SER U . n B 2 249 HIS 249 249 249 HIS HIS U . n B 2 250 VAL 250 250 250 VAL VAL U . n B 2 251 ALA 251 251 251 ALA ALA U . n B 2 252 ASP 252 252 252 ASP ASP U . n B 2 253 SER 253 253 253 SER SER U . n B 2 254 PHE 254 254 254 PHE PHE U . n B 2 255 PRO 255 255 255 PRO PRO U . n B 2 256 THR 256 256 256 THR THR U . n B 2 257 HIS 257 257 257 HIS HIS U . n B 2 258 LEU 258 258 258 LEU LEU U . n B 2 259 ASN 259 259 259 ASN ASN U . n B 2 260 VAL 260 260 260 VAL VAL U . n B 2 261 SER 261 261 261 SER SER U . n B 2 262 VAL 262 262 262 VAL VAL U . n B 2 263 SER 263 263 263 SER SER U . n B 2 264 CYS 264 264 264 CYS CYS U . n B 2 265 CYS 265 265 265 CYS CYS U . n B 2 266 HIS 266 266 266 HIS HIS U . n B 2 267 GLY 267 267 267 GLY GLY U . n B 2 268 SER 268 268 268 SER SER U . n B 2 269 GLY 269 269 269 GLY GLY U . n B 2 270 CYS 270 270 270 CYS CYS U . n B 2 271 ASN 271 271 271 ASN ASN U . n B 2 272 SER 272 272 272 SER SER U . n B 2 273 PRO 273 273 273 PRO PRO U . n B 2 274 THR 274 274 274 THR THR U . n B 2 275 GLY 275 275 ? ? ? U . n B 2 276 GLY 276 276 ? ? ? U . n B 2 277 ALA 277 277 ? ? ? U . n C 1 1 GLY 1 1 ? ? ? B . n C 1 2 SER 2 2 ? ? ? B . n C 1 3 VAL 3 3 ? ? ? B . n C 1 4 LEU 4 4 ? ? ? B . n C 1 5 GLY 5 5 ? ? ? B . n C 1 6 ALA 6 6 ? ? ? B . n C 1 7 PRO 7 7 ? ? ? B . n C 1 8 ASP 8 8 8 ASP ASP B . n C 1 9 GLU 9 9 9 GLU GLU B . n C 1 10 SER 10 10 10 SER SER B . n C 1 11 ASN 11 11 11 ASN ASN B . n C 1 12 CYS 12 12 12 CYS CYS B . n C 1 13 GLY 13 13 13 GLY GLY B . n C 1 14 CYS 14 14 14 CYS CYS B . n C 1 15 GLN 15 15 15 GLN GLN B . n C 1 16 ASN 16 16 16 ASN ASN B . n C 1 17 GLY 17 17 17 GLY GLY B . n C 1 18 GLY 18 18 18 GLY GLY B . n C 1 19 VAL 19 19 19 VAL VAL B . n C 1 20 CYS 20 20 20 CYS CYS B . n C 1 21 VAL 21 21 21 VAL VAL B . n C 1 22 SER 22 22 22 SER SER B . n C 1 23 TYR 23 23 23 TYR TYR B . n C 1 24 LYS 24 24 24 LYS LYS B . n C 1 25 TYR 25 25 25 TYR TYR B . n C 1 26 PHE 26 26 26 PHE PHE B . n C 1 27 SER 27 27 27 SER SER B . n C 1 28 ARG 28 28 28 ARG ARG B . n C 1 29 ILE 29 29 29 ILE ILE B . n C 1 30 ARG 30 30 30 ARG ARG B . n C 1 31 ARG 31 31 31 ARG ARG B . n C 1 32 CYS 32 32 32 CYS CYS B . n C 1 33 SER 33 33 33 SER SER B . n C 1 34 CYS 34 34 34 CYS CYS B . n C 1 35 PRO 35 35 35 PRO PRO B . n C 1 36 ARG 36 36 36 ARG ARG B . n C 1 37 LYS 37 37 37 LYS LYS B . n C 1 38 PHE 38 38 38 PHE PHE B . n C 1 39 GLN 39 39 39 GLN GLN B . n C 1 40 GLY 40 40 40 GLY GLY B . n C 1 41 GLU 41 41 41 GLU GLU B . n C 1 42 HIS 42 42 42 HIS HIS B . n C 1 43 CYS 43 43 43 CYS CYS B . n C 1 44 GLU 44 44 44 GLU GLU B . n C 1 45 ILE 45 45 45 ILE ILE B . n C 1 46 ASP 46 46 46 ASP ASP B . n C 1 47 ALA 47 47 47 ALA ALA B . n C 1 48 SER 48 48 48 SER SER B . n C 1 49 LYS 49 49 49 LYS LYS B . n C 1 50 THR 50 50 50 THR THR B . n C 1 51 CYS 51 51 51 CYS CYS B . n C 1 52 TYR 52 52 52 TYR TYR B . n C 1 53 HIS 53 53 53 HIS HIS B . n C 1 54 GLY 54 54 54 GLY GLY B . n C 1 55 ASN 55 55 55 ASN ASN B . n C 1 56 GLY 56 56 56 GLY GLY B . n C 1 57 ASP 57 57 57 ASP ASP B . n C 1 58 SER 58 58 58 SER SER B . n C 1 59 TYR 59 59 59 TYR TYR B . n C 1 60 ARG 60 60 60 ARG ARG B . n C 1 61 GLY 61 61 61 GLY GLY B . n C 1 62 LYS 62 62 62 LYS LYS B . n C 1 63 ALA 63 63 63 ALA ALA B . n C 1 64 ASN 64 64 64 ASN ASN B . n C 1 65 THR 65 65 65 THR THR B . n C 1 66 ASP 66 66 66 ASP ASP B . n C 1 67 THR 67 67 67 THR THR B . n C 1 68 LYS 68 68 68 LYS LYS B . n C 1 69 GLY 69 69 69 GLY GLY B . n C 1 70 ARG 70 70 70 ARG ARG B . n C 1 71 PRO 71 71 71 PRO PRO B . n C 1 72 CYS 72 72 72 CYS CYS B . n C 1 73 LEU 73 73 73 LEU LEU B . n C 1 74 ALA 74 74 74 ALA ALA B . n C 1 75 TRP 75 75 75 TRP TRP B . n C 1 76 ASN 76 76 76 ASN ASN B . n C 1 77 ALA 77 77 77 ALA ALA B . n C 1 78 PRO 78 78 78 PRO PRO B . n C 1 79 ALA 79 79 79 ALA ALA B . n C 1 80 VAL 80 80 80 VAL VAL B . n C 1 81 LEU 81 81 81 LEU LEU B . n C 1 82 GLN 82 82 82 GLN GLN B . n C 1 83 LYS 83 83 83 LYS LYS B . n C 1 84 PRO 84 84 84 PRO PRO B . n C 1 85 TYR 85 85 85 TYR TYR B . n C 1 86 ASN 86 86 86 ASN ASN B . n C 1 87 ALA 87 87 87 ALA ALA B . n C 1 88 HIS 88 88 88 HIS HIS B . n C 1 89 ARG 89 89 89 ARG ARG B . n C 1 90 PRO 90 90 90 PRO PRO B . n C 1 91 ASP 91 91 91 ASP ASP B . n C 1 92 ALA 92 92 92 ALA ALA B . n C 1 93 ILE 93 93 93 ILE ILE B . n C 1 94 SER 94 94 94 SER SER B . n C 1 95 LEU 95 95 95 LEU LEU B . n C 1 96 GLY 96 96 96 GLY GLY B . n C 1 97 LEU 97 97 97 LEU LEU B . n C 1 98 GLY 98 98 98 GLY GLY B . n C 1 99 LYS 99 99 99 LYS LYS B . n C 1 100 HIS 100 100 100 HIS HIS B . n C 1 101 ASN 101 101 101 ASN ASN B . n C 1 102 TYR 102 102 102 TYR TYR B . n C 1 103 CYS 103 103 103 CYS CYS B . n C 1 104 ARG 104 104 104 ARG ARG B . n C 1 105 ASN 105 105 105 ASN ASN B . n C 1 106 PRO 106 106 106 PRO PRO B . n C 1 107 ASP 107 107 107 ASP ASP B . n C 1 108 ASN 108 108 108 ASN ASN B . n C 1 109 GLN 109 109 109 GLN GLN B . n C 1 110 LYS 110 110 110 LYS LYS B . n C 1 111 ARG 111 111 111 ARG ARG B . n C 1 112 PRO 112 112 112 PRO PRO B . n C 1 113 TRP 113 113 113 TRP TRP B . n C 1 114 CYS 114 114 114 CYS CYS B . n C 1 115 TYR 115 115 115 TYR TYR B . n C 1 116 VAL 116 116 116 VAL VAL B . n C 1 117 GLN 117 117 117 GLN GLN B . n C 1 118 ILE 118 118 118 ILE ILE B . n C 1 119 GLY 119 119 119 GLY GLY B . n C 1 120 LEU 120 120 120 LEU LEU B . n C 1 121 ARG 121 121 121 ARG ARG B . n C 1 122 GLN 122 122 122 GLN GLN B . n C 1 123 PHE 123 123 123 PHE PHE B . n C 1 124 VAL 124 124 124 VAL VAL B . n C 1 125 GLN 125 125 125 GLN GLN B . n C 1 126 GLU 126 126 126 GLU GLU B . n C 1 127 CYS 127 127 127 CYS CYS B . n C 1 128 MET 128 128 128 MET MET B . n C 1 129 VAL 129 129 129 VAL VAL B . n C 1 130 HIS 130 130 130 HIS HIS B . n C 1 131 ASP 131 131 131 ASP ASP B . n C 1 132 CYS 132 132 132 CYS CYS B . n C 1 133 SER 133 133 ? ? ? B . n C 1 134 LEU 134 134 ? ? ? B . n D 2 1 LEU 1 1 1 LEU LEU V . n D 2 2 GLN 2 2 2 GLN GLN V . n D 2 3 CYS 3 3 3 CYS CYS V . n D 2 4 MET 4 4 4 MET MET V . n D 2 5 GLN 5 5 5 GLN GLN V . n D 2 6 CYS 6 6 6 CYS CYS V . n D 2 7 GLU 7 7 7 GLU GLU V . n D 2 8 SER 8 8 8 SER SER V . n D 2 9 ASN 9 9 9 ASN ASN V . n D 2 10 GLN 10 10 10 GLN GLN V . n D 2 11 SER 11 11 11 SER SER V . n D 2 12 CYS 12 12 12 CYS CYS V . n D 2 13 LEU 13 13 13 LEU LEU V . n D 2 14 VAL 14 14 14 VAL VAL V . n D 2 15 GLU 15 15 15 GLU GLU V . n D 2 16 GLU 16 16 16 GLU GLU V . n D 2 17 CYS 17 17 17 CYS CYS V . n D 2 18 ALA 18 18 18 ALA ALA V . n D 2 19 LEU 19 19 19 LEU LEU V . n D 2 20 GLY 20 20 20 GLY GLY V . n D 2 21 GLN 21 21 21 GLN GLN V . n D 2 22 ASP 22 22 22 ASP ASP V . n D 2 23 LEU 23 23 23 LEU LEU V . n D 2 24 CYS 24 24 24 CYS CYS V . n D 2 25 ARG 25 25 25 ARG ARG V . n D 2 26 THR 26 26 26 THR THR V . n D 2 27 THR 27 27 27 THR THR V . n D 2 28 VAL 28 28 28 VAL VAL V . n D 2 29 LEU 29 29 29 LEU LEU V . n D 2 30 ARG 30 30 30 ARG ARG V . n D 2 31 GLU 31 31 31 GLU GLU V . n D 2 32 TRP 32 32 32 TRP TRP V . n D 2 33 GLN 33 33 33 GLN GLN V . n D 2 34 ASP 34 34 34 ASP ASP V . n D 2 35 ASP 35 35 35 ASP ASP V . n D 2 36 ARG 36 36 36 ARG ARG V . n D 2 37 GLU 37 37 37 GLU GLU V . n D 2 38 LEU 38 38 38 LEU LEU V . n D 2 39 GLU 39 39 39 GLU GLU V . n D 2 40 VAL 40 40 40 VAL VAL V . n D 2 41 VAL 41 41 41 VAL VAL V . n D 2 42 THR 42 42 42 THR THR V . n D 2 43 ARG 43 43 43 ARG ARG V . n D 2 44 GLY 44 44 44 GLY GLY V . n D 2 45 CYS 45 45 45 CYS CYS V . n D 2 46 ALA 46 46 46 ALA ALA V . n D 2 47 HIS 47 47 47 HIS HIS V . n D 2 48 SER 48 48 48 SER SER V . n D 2 49 GLU 49 49 49 GLU GLU V . n D 2 50 LYS 50 50 50 LYS LYS V . n D 2 51 THR 51 51 51 THR THR V . n D 2 52 ASN 52 52 52 ASN ASN V . n D 2 53 ARG 53 53 53 ARG ARG V . n D 2 54 THR 54 54 54 THR THR V . n D 2 55 MET 55 55 55 MET MET V . n D 2 56 SER 56 56 56 SER SER V . n D 2 57 TYR 57 57 57 TYR TYR V . n D 2 58 ARG 58 58 58 ARG ARG V . n D 2 59 MET 59 59 59 MET MET V . n D 2 60 GLY 60 60 60 GLY GLY V . n D 2 61 SER 61 61 61 SER SER V . n D 2 62 MET 62 62 62 MET MET V . n D 2 63 ILE 63 63 63 ILE ILE V . n D 2 64 ILE 64 64 64 ILE ILE V . n D 2 65 SER 65 65 65 SER SER V . n D 2 66 LEU 66 66 66 LEU LEU V . n D 2 67 THR 67 67 67 THR THR V . n D 2 68 GLU 68 68 68 GLU GLU V . n D 2 69 THR 69 69 69 THR THR V . n D 2 70 VAL 70 70 70 VAL VAL V . n D 2 71 CYS 71 71 71 CYS CYS V . n D 2 72 ALA 72 72 72 ALA ALA V . n D 2 73 THR 73 73 73 THR THR V . n D 2 74 ASN 74 74 74 ASN ASN V . n D 2 75 LEU 75 75 75 LEU LEU V . n D 2 76 CYS 76 76 76 CYS CYS V . n D 2 77 ASN 77 77 77 ASN ASN V . n D 2 78 ARG 78 78 78 ARG ARG V . n D 2 79 PRO 79 79 79 PRO PRO V . n D 2 80 ARG 80 80 80 ARG ARG V . n D 2 81 PRO 81 81 81 PRO PRO V . n D 2 82 GLY 82 82 ? ? ? V . n D 2 83 ALA 83 83 ? ? ? V . n D 2 84 ARG 84 84 ? ? ? V . n D 2 85 GLY 85 85 ? ? ? V . n D 2 86 ARG 86 86 ? ? ? V . n D 2 87 ALA 87 87 ? ? ? V . n D 2 88 PHE 88 88 ? ? ? V . n D 2 89 PRO 89 89 ? ? ? V . n D 2 90 GLN 90 90 ? ? ? V . n D 2 91 GLY 91 91 ? ? ? V . n D 2 92 ARG 92 92 ? ? ? V . n D 2 93 TYR 93 93 93 TYR TYR V . n D 2 94 LEU 94 94 94 LEU LEU V . n D 2 95 GLU 95 95 95 GLU GLU V . n D 2 96 CYS 96 96 96 CYS CYS V . n D 2 97 ALA 97 97 97 ALA ALA V . n D 2 98 SER 98 98 98 SER SER V . n D 2 99 CYS 99 99 99 CYS CYS V . n D 2 100 THR 100 100 100 THR THR V . n D 2 101 SER 101 101 101 SER SER V . n D 2 102 LEU 102 102 102 LEU LEU V . n D 2 103 ASP 103 103 103 ASP ASP V . n D 2 104 GLN 104 104 104 GLN GLN V . n D 2 105 SER 105 105 105 SER SER V . n D 2 106 CYS 106 106 106 CYS CYS V . n D 2 107 GLU 107 107 107 GLU GLU V . n D 2 108 ARG 108 108 108 ARG ARG V . n D 2 109 GLY 109 109 109 GLY GLY V . n D 2 110 ARG 110 110 110 ARG ARG V . n D 2 111 GLU 111 111 111 GLU GLU V . n D 2 112 GLN 112 112 112 GLN GLN V . n D 2 113 SER 113 113 113 SER SER V . n D 2 114 LEU 114 114 114 LEU LEU V . n D 2 115 GLN 115 115 115 GLN GLN V . n D 2 116 CYS 116 116 116 CYS CYS V . n D 2 117 ARG 117 117 117 ARG ARG V . n D 2 118 TYR 118 118 118 TYR TYR V . n D 2 119 PRO 119 119 119 PRO PRO V . n D 2 120 THR 120 120 120 THR THR V . n D 2 121 GLU 121 121 121 GLU GLU V . n D 2 122 HIS 122 122 122 HIS HIS V . n D 2 123 CYS 123 123 123 CYS CYS V . n D 2 124 ILE 124 124 124 ILE ILE V . n D 2 125 GLU 125 125 125 GLU GLU V . n D 2 126 VAL 126 126 126 VAL VAL V . n D 2 127 VAL 127 127 127 VAL VAL V . n D 2 128 THR 128 128 128 THR THR V . n D 2 129 LEU 129 129 129 LEU LEU V . n D 2 130 GLN 130 130 130 GLN GLN V . n D 2 131 SER 131 131 131 SER SER V . n D 2 132 THR 132 132 132 THR THR V . n D 2 133 GLU 133 133 133 GLU GLU V . n D 2 134 ARG 134 134 134 ARG ARG V . n D 2 135 SER 135 135 135 SER SER V . n D 2 136 LEU 136 136 136 LEU LEU V . n D 2 137 LYS 137 137 137 LYS LYS V . n D 2 138 ASP 138 138 138 ASP ASP V . n D 2 139 GLU 139 139 139 GLU GLU V . n D 2 140 ASP 140 140 140 ASP ASP V . n D 2 141 TYR 141 141 141 TYR TYR V . n D 2 142 THR 142 142 142 THR THR V . n D 2 143 ARG 143 143 143 ARG ARG V . n D 2 144 GLY 144 144 144 GLY GLY V . n D 2 145 CYS 145 145 145 CYS CYS V . n D 2 146 GLY 146 146 146 GLY GLY V . n D 2 147 SER 147 147 147 SER SER V . n D 2 148 LEU 148 148 148 LEU LEU V . n D 2 149 PRO 149 149 149 PRO PRO V . n D 2 150 GLY 150 150 150 GLY GLY V . n D 2 151 CYS 151 151 151 CYS CYS V . n D 2 152 PRO 152 152 152 PRO PRO V . n D 2 153 GLY 153 153 153 GLY GLY V . n D 2 154 THR 154 154 154 THR THR V . n D 2 155 ALA 155 155 155 ALA ALA V . n D 2 156 GLY 156 156 156 GLY GLY V . n D 2 157 PHE 157 157 157 PHE PHE V . n D 2 158 HIS 158 158 158 HIS HIS V . n D 2 159 SER 159 159 159 SER SER V . n D 2 160 ASN 160 160 160 ASN ASN V . n D 2 161 GLN 161 161 161 GLN GLN V . n D 2 162 THR 162 162 162 THR THR V . n D 2 163 PHE 163 163 163 PHE PHE V . n D 2 164 HIS 164 164 164 HIS HIS V . n D 2 165 PHE 165 165 165 PHE PHE V . n D 2 166 LEU 166 166 166 LEU LEU V . n D 2 167 LYS 167 167 167 LYS LYS V . n D 2 168 CYS 168 168 168 CYS CYS V . n D 2 169 CYS 169 169 169 CYS CYS V . n D 2 170 ASN 170 170 170 ASN ASN V . n D 2 171 TYR 171 171 171 TYR TYR V . n D 2 172 THR 172 172 172 THR THR V . n D 2 173 HIS 173 173 173 HIS HIS V . n D 2 174 CYS 174 174 174 CYS CYS V . n D 2 175 ASN 175 175 175 ASN ASN V . n D 2 176 GLY 176 176 176 GLY GLY V . n D 2 177 GLY 177 177 177 GLY GLY V . n D 2 178 PRO 178 178 178 PRO PRO V . n D 2 179 VAL 179 179 179 VAL VAL V . n D 2 180 LEU 180 180 180 LEU LEU V . n D 2 181 ASP 181 181 181 ASP ASP V . n D 2 182 LEU 182 182 182 LEU LEU V . n D 2 183 GLN 183 183 183 GLN GLN V . n D 2 184 SER 184 184 184 SER SER V . n D 2 185 PHE 185 185 185 PHE PHE V . n D 2 186 PRO 186 186 186 PRO PRO V . n D 2 187 PRO 187 187 187 PRO PRO V . n D 2 188 ASN 188 188 188 ASN ASN V . n D 2 189 GLY 189 189 189 GLY GLY V . n D 2 190 PHE 190 190 190 PHE PHE V . n D 2 191 GLN 191 191 191 GLN GLN V . n D 2 192 CYS 192 192 192 CYS CYS V . n D 2 193 TYR 193 193 193 TYR TYR V . n D 2 194 SER 194 194 194 SER SER V . n D 2 195 CYS 195 195 195 CYS CYS V . n D 2 196 GLU 196 196 196 GLU GLU V . n D 2 197 GLY 197 197 197 GLY GLY V . n D 2 198 ASN 198 198 198 ASN ASN V . n D 2 199 ASN 199 199 199 ASN ASN V . n D 2 200 THR 200 200 200 THR THR V . n D 2 201 LEU 201 201 201 LEU LEU V . n D 2 202 GLY 202 202 202 GLY GLY V . n D 2 203 CYS 203 203 203 CYS CYS V . n D 2 204 SER 204 204 204 SER SER V . n D 2 205 SER 205 205 205 SER SER V . n D 2 206 GLU 206 206 206 GLU GLU V . n D 2 207 GLU 207 207 207 GLU GLU V . n D 2 208 ALA 208 208 208 ALA ALA V . n D 2 209 SER 209 209 209 SER SER V . n D 2 210 LEU 210 210 210 LEU LEU V . n D 2 211 ILE 211 211 211 ILE ILE V . n D 2 212 ASN 212 212 212 ASN ASN V . n D 2 213 CYS 213 213 213 CYS CYS V . n D 2 214 ARG 214 214 214 ARG ARG V . n D 2 215 GLY 215 215 215 GLY GLY V . n D 2 216 PRO 216 216 216 PRO PRO V . n D 2 217 MET 217 217 217 MET MET V . n D 2 218 ASN 218 218 218 ASN ASN V . n D 2 219 GLN 219 219 219 GLN GLN V . n D 2 220 CYS 220 220 220 CYS CYS V . n D 2 221 LEU 221 221 221 LEU LEU V . n D 2 222 VAL 222 222 222 VAL VAL V . n D 2 223 ALA 223 223 223 ALA ALA V . n D 2 224 THR 224 224 224 THR THR V . n D 2 225 GLY 225 225 225 GLY GLY V . n D 2 226 LEU 226 226 226 LEU LEU V . n D 2 227 ASP 227 227 227 ASP ASP V . n D 2 228 VAL 228 228 228 VAL VAL V . n D 2 229 LEU 229 229 ? ? ? V . n D 2 230 GLY 230 230 ? ? ? V . n D 2 231 ASN 231 231 ? ? ? V . n D 2 232 ARG 232 232 232 ARG ARG V . n D 2 233 SER 233 233 233 SER SER V . n D 2 234 TYR 234 234 234 TYR TYR V . n D 2 235 THR 235 235 235 THR THR V . n D 2 236 VAL 236 236 236 VAL VAL V . n D 2 237 ARG 237 237 237 ARG ARG V . n D 2 238 GLY 238 238 238 GLY GLY V . n D 2 239 CYS 239 239 239 CYS CYS V . n D 2 240 ALA 240 240 240 ALA ALA V . n D 2 241 THR 241 241 241 THR THR V . n D 2 242 ALA 242 242 242 ALA ALA V . n D 2 243 SER 243 243 243 SER SER V . n D 2 244 TRP 244 244 244 TRP TRP V . n D 2 245 CYS 245 245 245 CYS CYS V . n D 2 246 GLN 246 246 246 GLN GLN V . n D 2 247 GLY 247 247 247 GLY GLY V . n D 2 248 SER 248 248 248 SER SER V . n D 2 249 HIS 249 249 249 HIS HIS V . n D 2 250 VAL 250 250 250 VAL VAL V . n D 2 251 ALA 251 251 251 ALA ALA V . n D 2 252 ASP 252 252 252 ASP ASP V . n D 2 253 SER 253 253 253 SER SER V . n D 2 254 PHE 254 254 254 PHE PHE V . n D 2 255 PRO 255 255 255 PRO PRO V . n D 2 256 THR 256 256 256 THR THR V . n D 2 257 HIS 257 257 257 HIS HIS V . n D 2 258 LEU 258 258 258 LEU LEU V . n D 2 259 ASN 259 259 259 ASN ASN V . n D 2 260 VAL 260 260 260 VAL VAL V . n D 2 261 SER 261 261 261 SER SER V . n D 2 262 VAL 262 262 262 VAL VAL V . n D 2 263 SER 263 263 263 SER SER V . n D 2 264 CYS 264 264 264 CYS CYS V . n D 2 265 CYS 265 265 265 CYS CYS V . n D 2 266 HIS 266 266 266 HIS HIS V . n D 2 267 GLY 267 267 267 GLY GLY V . n D 2 268 SER 268 268 268 SER SER V . n D 2 269 GLY 269 269 269 GLY GLY V . n D 2 270 CYS 270 270 270 CYS CYS V . n D 2 271 ASN 271 271 271 ASN ASN V . n D 2 272 SER 272 272 272 SER SER V . n D 2 273 PRO 273 273 273 PRO PRO V . n D 2 274 THR 274 274 274 THR THR V . n D 2 275 GLY 275 275 ? ? ? V . n D 2 276 GLY 276 276 ? ? ? V . n D 2 277 ALA 277 277 ? ? ? V . n # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 B ASN 52 U ASN 52 ? ASN 'GLYCOSYLATION SITE' 2 B ASN 170 U ASN 170 ? ASN 'GLYCOSYLATION SITE' 3 D ASN 52 V ASN 52 ? ASN 'GLYCOSYLATION SITE' 4 D ASN 160 V ASN 160 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 259 U ASN 259 ? ASN 'GLYCOSYLATION SITE' 6 D ASN 259 V ASN 259 ? ASN 'GLYCOSYLATION SITE' 7 D ASN 170 V ASN 170 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA dimeric 2 2 author_and_software_defined_assembly PISA dimeric 2 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,B,E,F,G,H,I 2 1 C,D,J,K,L,M,N # loop_ _pdbx_struct_assembly_prop.biol_id _pdbx_struct_assembly_prop.type _pdbx_struct_assembly_prop.value _pdbx_struct_assembly_prop.details 1 'ABSA (A^2)' 3750 ? 1 MORE 1 ? 1 'SSA (A^2)' 20340 ? 2 'ABSA (A^2)' 3600 ? 2 MORE -1 ? 2 'SSA (A^2)' 19940 ? # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-02-02 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' Advisory 2 2 'Structure model' 'Refinement description' 3 2 'Structure model' 'Version format compliance' # loop_ _pdbx_refine_tls.pdbx_refine_id _pdbx_refine_tls.id _pdbx_refine_tls.details _pdbx_refine_tls.method _pdbx_refine_tls.origin_x _pdbx_refine_tls.origin_y _pdbx_refine_tls.origin_z _pdbx_refine_tls.T[1][1] _pdbx_refine_tls.T[2][2] _pdbx_refine_tls.T[3][3] _pdbx_refine_tls.T[1][2] _pdbx_refine_tls.T[1][3] _pdbx_refine_tls.T[2][3] _pdbx_refine_tls.L[1][1] _pdbx_refine_tls.L[2][2] _pdbx_refine_tls.L[3][3] _pdbx_refine_tls.L[1][2] _pdbx_refine_tls.L[1][3] _pdbx_refine_tls.L[2][3] _pdbx_refine_tls.S[1][1] _pdbx_refine_tls.S[2][2] _pdbx_refine_tls.S[3][3] _pdbx_refine_tls.S[1][2] _pdbx_refine_tls.S[1][3] _pdbx_refine_tls.S[2][3] _pdbx_refine_tls.S[2][1] _pdbx_refine_tls.S[3][1] _pdbx_refine_tls.S[3][2] 'X-RAY DIFFRACTION' 1 ? refined 21.3220 -3.0670 14.9170 0.1706 0.1635 0.0618 -0.0146 0.0515 -0.0824 1.4104 3.9989 3.6870 0.1777 -0.3156 -0.5502 -0.0879 0.0181 0.0698 0.1515 -0.1565 -0.2343 -0.3706 0.2697 0.1155 'X-RAY DIFFRACTION' 2 ? refined 6.5640 1.9870 42.2730 0.1585 0.0829 0.1411 0.0120 0.0983 -0.0686 5.4312 5.4130 7.0463 -0.7627 1.6768 0.1041 0.0236 0.1342 -0.1578 -0.6408 0.6719 0.2690 0.6028 -0.6398 -0.1852 'X-RAY DIFFRACTION' 3 ? refined 37.1640 30.2580 32.4060 0.1815 0.1117 0.1254 0.1020 -0.0217 0.0032 3.0315 3.3545 2.3165 0.7674 0.7112 -0.8733 0.2566 -0.1850 -0.0716 -0.0129 -0.3642 -0.3909 0.2050 0.1574 0.2630 'X-RAY DIFFRACTION' 4 ? refined 9.9440 37.3650 17.9420 0.2175 0.1676 0.3508 0.0648 -0.1062 -0.0342 3.2279 5.8826 10.1037 -0.8602 0.1298 -3.9270 -0.1535 0.2941 -0.1406 -0.0056 0.4157 1.0512 -0.0946 -0.7888 -1.1924 'X-RAY DIFFRACTION' 5 ? refined 41.2280 5.0530 3.9560 0.7211 0.7776 0.5425 -0.2960 0.3203 0.0172 7.8211 11.0619 5.0973 -1.1741 -2.2019 2.6207 -0.5267 0.2665 0.2602 0.0851 0.3743 -1.2302 0.2199 -0.2805 1.3371 'X-RAY DIFFRACTION' 6 ? refined 48.4090 37.9830 52.2530 0.6272 0.2154 0.4145 -0.1070 -0.2094 0.0230 5.5129 10.4136 8.4932 -1.8222 2.0412 -0.1608 -0.2303 -0.3199 0.5501 -0.3984 0.0233 0.1398 0.2414 -1.2601 0.4078 # loop_ _pdbx_refine_tls_group.pdbx_refine_id _pdbx_refine_tls_group.id _pdbx_refine_tls_group.refine_tls_id _pdbx_refine_tls_group.beg_auth_asym_id _pdbx_refine_tls_group.beg_auth_seq_id _pdbx_refine_tls_group.end_auth_asym_id _pdbx_refine_tls_group.end_auth_seq_id _pdbx_refine_tls_group.selection_details _pdbx_refine_tls_group.beg_label_asym_id _pdbx_refine_tls_group.beg_label_seq_id _pdbx_refine_tls_group.end_label_asym_id _pdbx_refine_tls_group.end_label_seq_id _pdbx_refine_tls_group.selection 'X-RAY DIFFRACTION' 1 1 A 11 A 47 ? . . . . ? 'X-RAY DIFFRACTION' 2 1 U 1 U 184 ? . . . . ? 'X-RAY DIFFRACTION' 3 2 A 48 A 131 ? . . . . ? 'X-RAY DIFFRACTION' 4 3 B 11 B 47 ? . . . . ? 'X-RAY DIFFRACTION' 5 3 V 1 V 184 ? . . . . ? 'X-RAY DIFFRACTION' 6 4 B 48 B 131 ? . . . . ? 'X-RAY DIFFRACTION' 7 5 U 185 U 274 ? . . . . ? 'X-RAY DIFFRACTION' 8 6 V 185 V 274 ? . . . . ? # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal HKL-2000 'data collection' . ? 1 AMoRE phasing . ? 2 REFMAC refinement 5.5.0102 ? 3 HKL-2000 'data reduction' . ? 4 HKL-2000 'data scaling' . ? 5 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 O4 U NAG 1052 ? ? C1 U NAG 1053 ? ? 1.58 2 1 O4 V NAG 1052 ? ? C1 V NAG 1053 ? ? 1.61 3 1 ND2 U ASN 160 ? ? C1 U NAG 1160 ? ? 1.63 4 1 OD1 V ASN 259 ? ? N2 V NAG 1259 ? ? 1.84 5 1 O4 V NAG 1052 ? ? O5 V NAG 1053 ? ? 1.88 6 1 OD1 V ASN 259 ? ? C7 V NAG 1259 ? ? 1.89 7 1 OD1 V ASN 259 ? ? C8 V NAG 1259 ? ? 1.93 8 1 O4 U NAG 1052 ? ? C2 U NAG 1053 ? ? 1.93 9 1 ND2 V ASN 160 ? ? C2 V NAG 1160 ? ? 1.94 10 1 OD1 V ASN 259 ? ? C2 V NAG 1259 ? ? 1.96 11 1 O4 U NAG 1052 ? ? O5 U NAG 1053 ? ? 1.97 12 1 ND2 V ASN 259 ? ? O5 V NAG 1259 ? ? 2.02 13 1 ND2 V ASN 259 ? ? C2 V NAG 1259 ? ? 2.05 14 1 O V SER 205 ? ? OE1 V GLU 207 ? ? 2.11 15 1 ND2 U ASN 170 ? ? O5 U NAG 1170 ? ? 2.11 16 1 N A SER 22 ? ? O U LYS 137 ? ? 2.15 17 1 ND2 V ASN 170 ? ? O5 V NAG 1170 ? ? 2.17 18 1 O U HIS 249 ? ? OD2 U ASP 252 ? ? 2.18 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CA A CYS 51 ? ? CB A CYS 51 ? ? SG A CYS 51 ? ? 121.72 114.20 7.52 1.10 N 2 1 CA A CYS 103 ? ? CB A CYS 103 ? ? SG A CYS 103 ? ? 101.50 114.00 -12.50 1.80 N 3 1 CA U CYS 24 ? ? CB U CYS 24 ? ? SG U CYS 24 ? ? 102.29 114.00 -11.71 1.80 N 4 1 C B ARG 70 ? ? N B PRO 71 ? ? CA B PRO 71 ? ? 128.61 119.30 9.31 1.50 Y 5 1 C V ARG 78 ? ? N V PRO 79 ? ? CA V PRO 79 ? ? 128.78 119.30 9.48 1.50 Y 6 1 C V ARG 78 ? ? N V PRO 79 ? ? CD V PRO 79 ? ? 108.63 128.40 -19.77 2.10 Y 7 1 O V HIS 158 ? ? C V HIS 158 ? ? N V SER 159 ? ? 133.00 122.70 10.30 1.60 Y 8 1 CA V CYS 168 ? ? CB V CYS 168 ? ? SG V CYS 168 ? ? 123.96 114.20 9.76 1.10 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER A 10 ? ? -131.71 -68.68 2 1 ASN A 11 ? ? 2.13 60.82 3 1 CYS A 12 ? ? -145.62 -2.67 4 1 ASN A 16 ? ? 55.66 -132.70 5 1 SER A 22 ? ? -105.99 -167.45 6 1 PHE A 26 ? ? -108.15 55.91 7 1 ARG A 28 ? ? 44.64 18.80 8 1 ASP A 57 ? ? -37.40 -29.24 9 1 THR A 67 ? ? -65.78 10.08 10 1 ARG A 70 ? ? -34.08 144.25 11 1 ALA A 77 ? ? -21.32 136.01 12 1 ARG A 89 ? ? -31.65 136.65 13 1 LYS A 99 ? ? -57.83 9.74 14 1 HIS A 100 ? ? -103.44 -163.36 15 1 ASN A 105 ? ? -155.04 73.92 16 1 ASP A 107 ? ? -71.73 -166.71 17 1 GLN A 109 ? ? 159.57 128.12 18 1 LYS A 110 ? ? -25.18 -68.41 19 1 VAL A 129 ? ? -1.36 107.99 20 1 CYS U 6 ? ? 172.61 116.52 21 1 GLU U 7 ? ? -62.50 -177.78 22 1 SER U 8 ? ? -41.28 -79.57 23 1 LEU U 19 ? ? -47.01 109.33 24 1 ASP U 22 ? ? -142.40 24.42 25 1 THR U 26 ? ? -150.89 74.65 26 1 GLN U 33 ? ? -172.46 142.46 27 1 ASP U 34 ? ? 33.61 60.38 28 1 ASP U 35 ? ? 32.00 51.18 29 1 ALA U 46 ? ? -92.69 -118.45 30 1 ASN U 52 ? ? -46.37 104.83 31 1 ARG U 78 ? ? -147.22 -117.01 32 1 PRO U 79 ? ? -94.23 -61.42 33 1 CYS U 99 ? ? 152.61 161.21 34 1 ARG U 110 ? ? -172.23 147.05 35 1 GLU U 111 ? ? -173.65 100.34 36 1 THR U 120 ? ? 96.19 -20.55 37 1 THR U 132 ? ? 35.85 -120.93 38 1 GLU U 133 ? ? -96.49 30.93 39 1 ARG U 134 ? ? 10.91 119.65 40 1 LYS U 137 ? ? -98.07 48.53 41 1 GLU U 139 ? ? -47.84 152.84 42 1 CYS U 151 ? ? -76.90 -92.83 43 1 PHE U 165 ? ? -171.60 135.96 44 1 ASN U 170 ? ? -95.13 40.77 45 1 HIS U 173 ? ? 45.60 28.52 46 1 CYS U 174 ? ? -57.92 -3.84 47 1 PRO U 187 ? ? -47.76 93.72 48 1 GLU U 196 ? ? -158.28 84.76 49 1 ASN U 198 ? ? -146.83 -76.79 50 1 THR U 200 ? ? 66.81 -43.55 51 1 SER U 204 ? ? -162.08 -151.55 52 1 ASN U 218 ? ? -148.48 -1.72 53 1 THR U 241 ? ? -84.24 -157.65 54 1 HIS U 249 ? ? -47.06 -97.03 55 1 VAL U 250 ? ? -10.33 -57.96 56 1 PRO U 255 ? ? -16.07 -91.30 57 1 HIS U 257 ? ? -178.16 -165.56 58 1 LEU U 258 ? ? -59.74 -133.98 59 1 VAL U 260 ? ? 33.21 58.55 60 1 SER U 261 ? ? -37.92 133.04 61 1 PRO U 273 ? ? -35.74 66.75 62 1 SER B 10 ? ? -134.49 -74.85 63 1 ASN B 11 ? ? 100.70 -75.72 64 1 CYS B 14 ? ? 4.74 118.95 65 1 ASN B 16 ? ? 53.63 -112.82 66 1 LYS B 24 ? ? -6.20 -65.50 67 1 ARG B 28 ? ? 32.15 63.35 68 1 CYS B 32 ? ? -156.26 72.97 69 1 SER B 33 ? ? -55.88 107.11 70 1 GLU B 41 ? ? -47.57 -19.87 71 1 THR B 50 ? ? -132.07 -53.69 72 1 HIS B 53 ? ? -48.89 102.72 73 1 ARG B 60 ? ? -143.64 26.37 74 1 TRP B 75 ? ? -57.21 4.05 75 1 HIS B 88 ? ? -58.34 5.39 76 1 ALA B 92 ? ? 35.25 -96.90 77 1 ILE B 93 ? ? -16.94 -61.43 78 1 LEU B 95 ? ? -72.13 -115.63 79 1 ASN B 105 ? ? -108.33 65.94 80 1 MET B 128 ? ? -45.13 -87.96 81 1 VAL B 129 ? ? -7.72 116.71 82 1 ASN V 9 ? ? 29.98 33.76 83 1 ASP V 22 ? ? 165.86 37.00 84 1 GLN V 33 ? ? -161.43 77.69 85 1 ASP V 34 ? ? 58.44 96.93 86 1 GLU V 37 ? ? -50.85 104.64 87 1 ALA V 46 ? ? -103.46 -62.93 88 1 HIS V 47 ? ? 84.99 121.96 89 1 GLU V 49 ? ? -96.00 42.02 90 1 SER V 56 ? ? -173.27 124.94 91 1 LEU V 75 ? ? 35.55 38.08 92 1 ASN V 77 ? ? -117.53 63.40 93 1 ARG V 78 ? ? -106.20 -118.91 94 1 PRO V 79 ? ? -50.85 -110.99 95 1 ARG V 80 ? ? -39.93 132.85 96 1 LEU V 94 ? ? 41.84 121.82 97 1 GLN V 104 ? ? 74.85 39.41 98 1 CYS V 106 ? ? -77.93 -75.85 99 1 GLU V 107 ? ? -1.47 -65.05 100 1 GLU V 111 ? ? -36.05 -159.75 101 1 SER V 113 ? ? -0.96 122.56 102 1 ARG V 117 ? ? -63.72 -77.94 103 1 PRO V 119 ? ? -53.22 98.15 104 1 THR V 120 ? ? 140.95 16.00 105 1 GLN V 130 ? ? -128.79 -141.45 106 1 THR V 132 ? ? 15.98 -73.82 107 1 ARG V 134 ? ? 62.53 79.55 108 1 ASP V 138 ? ? -77.44 -169.14 109 1 PRO V 152 ? ? -60.58 96.37 110 1 ALA V 155 ? ? -172.10 143.94 111 1 THR V 172 ? ? -20.96 122.57 112 1 ASN V 175 ? ? -166.85 79.37 113 1 PRO V 178 ? ? -24.17 87.47 114 1 LEU V 180 ? ? -61.52 83.76 115 1 GLN V 183 ? ? -31.78 -33.40 116 1 CYS V 195 ? ? -179.68 142.50 117 1 GLU V 196 ? ? -171.80 93.61 118 1 ASN V 198 ? ? -152.81 -109.21 119 1 ASN V 199 ? ? -179.34 -118.84 120 1 SER V 204 ? ? -96.01 -134.06 121 1 GLU V 206 ? ? -75.75 45.16 122 1 SER V 209 ? ? -14.86 152.14 123 1 ASP V 227 ? ? -107.84 -82.92 124 1 HIS V 249 ? ? 17.82 -89.55 125 1 ASP V 252 ? ? -80.45 43.22 126 1 ASN V 259 ? ? 6.21 44.55 127 1 ASN V 271 ? ? -77.10 41.92 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 ARG _pdbx_validate_peptide_omega.auth_asym_id_1 V _pdbx_validate_peptide_omega.auth_seq_id_1 78 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 PRO _pdbx_validate_peptide_omega.auth_asym_id_2 V _pdbx_validate_peptide_omega.auth_seq_id_2 79 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega -137.59 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 N 1 U NAG 1053 ? O1 ? F NAG 1 O1 2 1 N 1 U NAG 1160 ? O1 ? G NAG 1 O1 3 1 N 1 V NAG 1053 ? O1 ? K NAG 1 O1 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A GLY 1 ? A GLY 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A VAL 3 ? A VAL 3 4 1 Y 1 A LEU 4 ? A LEU 4 5 1 Y 1 A GLY 5 ? A GLY 5 6 1 Y 1 A ALA 6 ? A ALA 6 7 1 Y 1 A PRO 7 ? A PRO 7 8 1 Y 1 A ASP 8 ? A ASP 8 9 1 Y 1 A SER 133 ? A SER 133 10 1 Y 1 A LEU 134 ? A LEU 134 11 1 Y 1 U GLY 82 ? B GLY 82 12 1 Y 1 U ALA 83 ? B ALA 83 13 1 Y 1 U ARG 84 ? B ARG 84 14 1 Y 1 U GLY 85 ? B GLY 85 15 1 Y 1 U ARG 86 ? B ARG 86 16 1 Y 1 U ALA 87 ? B ALA 87 17 1 Y 1 U PHE 88 ? B PHE 88 18 1 Y 1 U PRO 89 ? B PRO 89 19 1 Y 1 U GLN 90 ? B GLN 90 20 1 Y 1 U GLY 91 ? B GLY 91 21 1 Y 1 U ARG 92 ? B ARG 92 22 1 Y 1 U ASP 227 ? B ASP 227 23 1 Y 1 U VAL 228 ? B VAL 228 24 1 Y 1 U LEU 229 ? B LEU 229 25 1 Y 1 U GLY 230 ? B GLY 230 26 1 Y 1 U ASN 231 ? B ASN 231 27 1 Y 1 U GLY 275 ? B GLY 275 28 1 Y 1 U GLY 276 ? B GLY 276 29 1 Y 1 U ALA 277 ? B ALA 277 30 1 Y 1 B GLY 1 ? C GLY 1 31 1 Y 1 B SER 2 ? C SER 2 32 1 Y 1 B VAL 3 ? C VAL 3 33 1 Y 1 B LEU 4 ? C LEU 4 34 1 Y 1 B GLY 5 ? C GLY 5 35 1 Y 1 B ALA 6 ? C ALA 6 36 1 Y 1 B PRO 7 ? C PRO 7 37 1 Y 1 B SER 133 ? C SER 133 38 1 Y 1 B LEU 134 ? C LEU 134 39 1 Y 1 V GLY 82 ? D GLY 82 40 1 Y 1 V ALA 83 ? D ALA 83 41 1 Y 1 V ARG 84 ? D ARG 84 42 1 Y 1 V GLY 85 ? D GLY 85 43 1 Y 1 V ARG 86 ? D ARG 86 44 1 Y 1 V ALA 87 ? D ALA 87 45 1 Y 1 V PHE 88 ? D PHE 88 46 1 Y 1 V PRO 89 ? D PRO 89 47 1 Y 1 V GLN 90 ? D GLN 90 48 1 Y 1 V GLY 91 ? D GLY 91 49 1 Y 1 V ARG 92 ? D ARG 92 50 1 Y 1 V LEU 229 ? D LEU 229 51 1 Y 1 V GLY 230 ? D GLY 230 52 1 Y 1 V ASN 231 ? D ASN 231 53 1 Y 1 V GLY 275 ? D GLY 275 54 1 Y 1 V GLY 276 ? D GLY 276 55 1 Y 1 V ALA 277 ? D ALA 277 # _pdbx_entity_nonpoly.entity_id 3 _pdbx_entity_nonpoly.name N-ACETYL-D-GLUCOSAMINE _pdbx_entity_nonpoly.comp_id NAG # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code E 3 NAG 1 1052 1052 NAG NAG U . F 3 NAG 1 1053 1053 NAG NAG U . G 3 NAG 1 1160 1160 NAG NAG U . H 3 NAG 1 1170 1170 NAG NAG U . I 3 NAG 1 1259 1259 NAG NAG U . J 3 NAG 1 1052 1052 NAG NAG V . K 3 NAG 1 1053 1053 NAG NAG V . L 3 NAG 1 1170 1170 NAG NAG V . M 3 NAG 1 1160 1160 NAG NAG V . N 3 NAG 1 1259 1259 NAG NAG V . #