data_3K4Q # _entry.id 3K4Q # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3K4Q RCSB RCSB055543 WWPDB D_1000055543 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1ihp 'Aspergillus niger phytase' unspecified PDB 2gfi 'Debaryomyces castellii CBS 2923 phytase' unspecified PDB 1dkl 'Escherichia coli phytase' unspecified PDB 1dkq 'Escherichia coli phytase H17A mutant in complex with myo-inositol hexakisphosphate' unspecified PDB 1qfx 'Aspergillus niger pH 2.5 acid phosphatase' unspecified PDB 3k4p 'Aspergillus niger Phytase' unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 3K4Q _pdbx_database_status.recvd_initial_deposition_date 2009-10-06 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # _audit_author.name 'Oakley, A.J.' _audit_author.pdbx_ordinal 1 # _citation.id primary _citation.title 'The structure of Aspergillus niger phytase PhyA in complex with a phytate mimetic' _citation.journal_abbrev Biochem.Biophys.Res.Commun. _citation.journal_volume 397 _citation.page_first 745 _citation.page_last 749 _citation.year 2010 _citation.journal_id_ASTM BBRCA9 _citation.country US _citation.journal_id_ISSN 0006-291X _citation.journal_id_CSD 0146 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 20541524 _citation.pdbx_database_id_DOI 10.1016/j.bbrc.2010.06.024 # _citation_author.citation_id primary _citation_author.name 'Oakley, A.J.' _citation_author.ordinal 1 # _cell.entry_id 3K4Q _cell.length_a 70.699 _cell.length_b 87.571 _cell.length_c 81.765 _cell.angle_alpha 90.00 _cell.angle_beta 110.61 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 3K4Q _symmetry.space_group_name_H-M 'P 1 21 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 4 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man '3-phytase A' 48888.996 2 3.1.3.8 ? ? ? 2 non-polymer syn D-MYO-INOSITOL-HEXASULPHATE 660.535 2 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 8 ? ? ? ? 4 water nat water 18.015 363 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name '3 phytase A, Myo-inositol-hexaphosphate 3-phosphohydrolase A, Myo-inositol hexakisphosphate phosphohydrolase A' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;ASRNQSSCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQ QNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLK DPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDM CSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLD SSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVR VLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA ; _entity_poly.pdbx_seq_one_letter_code_can ;ASRNQSSCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQ QNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLK DPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDM CSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLD SSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVR VLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ALA n 1 2 SER n 1 3 ARG n 1 4 ASN n 1 5 GLN n 1 6 SER n 1 7 SER n 1 8 CYS n 1 9 ASP n 1 10 THR n 1 11 VAL n 1 12 ASP n 1 13 GLN n 1 14 GLY n 1 15 TYR n 1 16 GLN n 1 17 CYS n 1 18 PHE n 1 19 SER n 1 20 GLU n 1 21 THR n 1 22 SER n 1 23 HIS n 1 24 LEU n 1 25 TRP n 1 26 GLY n 1 27 GLN n 1 28 TYR n 1 29 ALA n 1 30 PRO n 1 31 PHE n 1 32 PHE n 1 33 SER n 1 34 LEU n 1 35 ALA n 1 36 ASN n 1 37 GLU n 1 38 SER n 1 39 VAL n 1 40 ILE n 1 41 SER n 1 42 PRO n 1 43 GLU n 1 44 VAL n 1 45 PRO n 1 46 ALA n 1 47 GLY n 1 48 CYS n 1 49 ARG n 1 50 VAL n 1 51 THR n 1 52 PHE n 1 53 ALA n 1 54 GLN n 1 55 VAL n 1 56 LEU n 1 57 SER n 1 58 ARG n 1 59 HIS n 1 60 GLY n 1 61 ALA n 1 62 ARG n 1 63 TYR n 1 64 PRO n 1 65 THR n 1 66 ASP n 1 67 SER n 1 68 LYS n 1 69 GLY n 1 70 LYS n 1 71 LYS n 1 72 TYR n 1 73 SER n 1 74 ALA n 1 75 LEU n 1 76 ILE n 1 77 GLU n 1 78 GLU n 1 79 ILE n 1 80 GLN n 1 81 GLN n 1 82 ASN n 1 83 ALA n 1 84 THR n 1 85 THR n 1 86 PHE n 1 87 ASP n 1 88 GLY n 1 89 LYS n 1 90 TYR n 1 91 ALA n 1 92 PHE n 1 93 LEU n 1 94 LYS n 1 95 THR n 1 96 TYR n 1 97 ASN n 1 98 TYR n 1 99 SER n 1 100 LEU n 1 101 GLY n 1 102 ALA n 1 103 ASP n 1 104 ASP n 1 105 LEU n 1 106 THR n 1 107 PRO n 1 108 PHE n 1 109 GLY n 1 110 GLU n 1 111 GLN n 1 112 GLU n 1 113 LEU n 1 114 VAL n 1 115 ASN n 1 116 SER n 1 117 GLY n 1 118 ILE n 1 119 LYS n 1 120 PHE n 1 121 TYR n 1 122 GLN n 1 123 ARG n 1 124 TYR n 1 125 GLU n 1 126 SER n 1 127 LEU n 1 128 THR n 1 129 ARG n 1 130 ASN n 1 131 ILE n 1 132 VAL n 1 133 PRO n 1 134 PHE n 1 135 ILE n 1 136 ARG n 1 137 SER n 1 138 SER n 1 139 GLY n 1 140 SER n 1 141 SER n 1 142 ARG n 1 143 VAL n 1 144 ILE n 1 145 ALA n 1 146 SER n 1 147 GLY n 1 148 LYS n 1 149 LYS n 1 150 PHE n 1 151 ILE n 1 152 GLU n 1 153 GLY n 1 154 PHE n 1 155 GLN n 1 156 SER n 1 157 THR n 1 158 LYS n 1 159 LEU n 1 160 LYS n 1 161 ASP n 1 162 PRO n 1 163 ARG n 1 164 ALA n 1 165 GLN n 1 166 PRO n 1 167 GLY n 1 168 GLN n 1 169 SER n 1 170 SER n 1 171 PRO n 1 172 LYS n 1 173 ILE n 1 174 ASP n 1 175 VAL n 1 176 VAL n 1 177 ILE n 1 178 SER n 1 179 GLU n 1 180 ALA n 1 181 SER n 1 182 SER n 1 183 SER n 1 184 ASN n 1 185 ASN n 1 186 THR n 1 187 LEU n 1 188 ASP n 1 189 PRO n 1 190 GLY n 1 191 THR n 1 192 CYS n 1 193 THR n 1 194 VAL n 1 195 PHE n 1 196 GLU n 1 197 ASP n 1 198 SER n 1 199 GLU n 1 200 LEU n 1 201 ALA n 1 202 ASP n 1 203 THR n 1 204 VAL n 1 205 GLU n 1 206 ALA n 1 207 ASN n 1 208 PHE n 1 209 THR n 1 210 ALA n 1 211 THR n 1 212 PHE n 1 213 VAL n 1 214 PRO n 1 215 SER n 1 216 ILE n 1 217 ARG n 1 218 GLN n 1 219 ARG n 1 220 LEU n 1 221 GLU n 1 222 ASN n 1 223 ASP n 1 224 LEU n 1 225 SER n 1 226 GLY n 1 227 VAL n 1 228 THR n 1 229 LEU n 1 230 THR n 1 231 ASP n 1 232 THR n 1 233 GLU n 1 234 VAL n 1 235 THR n 1 236 TYR n 1 237 LEU n 1 238 MET n 1 239 ASP n 1 240 MET n 1 241 CYS n 1 242 SER n 1 243 PHE n 1 244 ASP n 1 245 THR n 1 246 ILE n 1 247 SER n 1 248 THR n 1 249 SER n 1 250 THR n 1 251 VAL n 1 252 ASP n 1 253 THR n 1 254 LYS n 1 255 LEU n 1 256 SER n 1 257 PRO n 1 258 PHE n 1 259 CYS n 1 260 ASP n 1 261 LEU n 1 262 PHE n 1 263 THR n 1 264 HIS n 1 265 ASP n 1 266 GLU n 1 267 TRP n 1 268 ILE n 1 269 ASN n 1 270 TYR n 1 271 ASP n 1 272 TYR n 1 273 LEU n 1 274 GLN n 1 275 SER n 1 276 LEU n 1 277 LYS n 1 278 LYS n 1 279 TYR n 1 280 TYR n 1 281 GLY n 1 282 HIS n 1 283 GLY n 1 284 ALA n 1 285 GLY n 1 286 ASN n 1 287 PRO n 1 288 LEU n 1 289 GLY n 1 290 PRO n 1 291 THR n 1 292 GLN n 1 293 GLY n 1 294 VAL n 1 295 GLY n 1 296 TYR n 1 297 ALA n 1 298 ASN n 1 299 GLU n 1 300 LEU n 1 301 ILE n 1 302 ALA n 1 303 ARG n 1 304 LEU n 1 305 THR n 1 306 HIS n 1 307 SER n 1 308 PRO n 1 309 VAL n 1 310 HIS n 1 311 ASP n 1 312 ASP n 1 313 THR n 1 314 SER n 1 315 SER n 1 316 ASN n 1 317 HIS n 1 318 THR n 1 319 LEU n 1 320 ASP n 1 321 SER n 1 322 SER n 1 323 PRO n 1 324 ALA n 1 325 THR n 1 326 PHE n 1 327 PRO n 1 328 LEU n 1 329 ASN n 1 330 SER n 1 331 THR n 1 332 LEU n 1 333 TYR n 1 334 ALA n 1 335 ASP n 1 336 PHE n 1 337 SER n 1 338 HIS n 1 339 ASP n 1 340 ASN n 1 341 GLY n 1 342 ILE n 1 343 ILE n 1 344 SER n 1 345 ILE n 1 346 LEU n 1 347 PHE n 1 348 ALA n 1 349 LEU n 1 350 GLY n 1 351 LEU n 1 352 TYR n 1 353 ASN n 1 354 GLY n 1 355 THR n 1 356 LYS n 1 357 PRO n 1 358 LEU n 1 359 SER n 1 360 THR n 1 361 THR n 1 362 THR n 1 363 VAL n 1 364 GLU n 1 365 ASN n 1 366 ILE n 1 367 THR n 1 368 GLN n 1 369 THR n 1 370 ASP n 1 371 GLY n 1 372 PHE n 1 373 SER n 1 374 SER n 1 375 ALA n 1 376 TRP n 1 377 THR n 1 378 VAL n 1 379 PRO n 1 380 PHE n 1 381 ALA n 1 382 SER n 1 383 ARG n 1 384 LEU n 1 385 TYR n 1 386 VAL n 1 387 GLU n 1 388 MET n 1 389 MET n 1 390 GLN n 1 391 CYS n 1 392 GLN n 1 393 ALA n 1 394 GLU n 1 395 GLN n 1 396 GLU n 1 397 PRO n 1 398 LEU n 1 399 VAL n 1 400 ARG n 1 401 VAL n 1 402 LEU n 1 403 VAL n 1 404 ASN n 1 405 ASP n 1 406 ARG n 1 407 VAL n 1 408 VAL n 1 409 PRO n 1 410 LEU n 1 411 HIS n 1 412 GLY n 1 413 CYS n 1 414 PRO n 1 415 VAL n 1 416 ASP n 1 417 ALA n 1 418 LEU n 1 419 GLY n 1 420 ARG n 1 421 CYS n 1 422 THR n 1 423 ARG n 1 424 ASP n 1 425 SER n 1 426 PHE n 1 427 VAL n 1 428 ARG n 1 429 GLY n 1 430 LEU n 1 431 SER n 1 432 PHE n 1 433 ALA n 1 434 ARG n 1 435 SER n 1 436 GLY n 1 437 GLY n 1 438 ASP n 1 439 TRP n 1 440 ALA n 1 441 GLU n 1 442 CYS n 1 443 PHE n 1 444 ALA n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name ? _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene PhyA _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Aspergillus niger' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 5061 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Aspergillus niger' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 5061 _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code PHYA_ASPNG _struct_ref.pdbx_db_accession P34752 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;ASRNQSSCDTVDQGYQCFSETSHLWGQYAPFFSLANESVISPEVPAGCRVTFAQVLSRHGARYPTDSKGKKYSALIEEIQ QNATTFDGKYAFLKTYNYSLGADDLTPFGEQELVNSGIKFYQRYESLTRNIVPFIRSSGSSRVIASGKKFIEGFQSTKLK DPRAQPGQSSPKIDVVISEASSSNNTLDPGTCTVFEDSELADTVEANFTATFVPSIRQRLENDLSGVTLTDTEVTYLMDM CSFDTISTSTVDTKLSPFCDLFTHDEWINYDYLQSLKKYYGHGAGNPLGPTQGVGYANELIARLTHSPVHDDTSSNHTLD SSPATFPLNSTLYADFSHDNGIISILFALGLYNGTKPLSTTTVENITQTDGFSSAWTVPFASRLYVEMMQCQAEQEPLVR VLVNDRVVPLHGCPVDALGRCTRDSFVRGLSFARSGGDWAECFA ; _struct_ref.pdbx_align_begin 24 _struct_ref.pdbx_db_isoform ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 3K4Q A 1 ? 444 ? P34752 24 ? 467 ? 1 444 2 1 3K4Q B 1 ? 444 ? P34752 24 ? 467 ? 1 444 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 IHS non-polymer . D-MYO-INOSITOL-HEXASULPHATE ? 'C6 H12 O24 S6' 660.535 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 3K4Q _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.42 _exptl_crystal.density_percent_sol 49.23 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 298 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 7 _exptl_crystal_grow.pdbx_details '25% (w/v) PEG 3350, 0.2M ammonium nitrate, pH 7, VAPOR DIFFUSION, HANGING DROP, temperature 298K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 315r' _diffrn_detector.pdbx_collection_date 2009-08-28 _diffrn_detector.details 'BEAMLINE OPTICS' # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'BEAMLINE OPTICS' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.953715 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'AUSTRALIAN SYNCHROTRON BEAMLINE MX2' _diffrn_source.pdbx_synchrotron_site 'Australian Synchrotron' _diffrn_source.pdbx_synchrotron_beamline MX2 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.953715 # _reflns.entry_id 3K4Q _reflns.observed_criterion_sigma_I -3 _reflns.observed_criterion_sigma_F -3 _reflns.d_resolution_low 76.53 _reflns.d_resolution_high 2.20 _reflns.number_obs 46790 _reflns.number_all 46790 _reflns.percent_possible_obs 96.1 _reflns.pdbx_Rmerge_I_obs 0.110 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 8.8 _reflns.B_iso_Wilson_estimate 26.0 _reflns.pdbx_redundancy 3.7 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_diffrn_id 1 _reflns.pdbx_ordinal 1 # _reflns_shell.d_res_high 2.20 _reflns_shell.d_res_low 2.32 _reflns_shell.percent_possible_all 97.9 _reflns_shell.Rmerge_I_obs 0.442 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs 2.4 _reflns_shell.pdbx_redundancy 3.8 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 6741 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_diffrn_id ? _reflns_shell.pdbx_ordinal 1 # _refine.entry_id 3K4Q _refine.ls_number_reflns_obs 44411 _refine.ls_number_reflns_all 44411 _refine.pdbx_ls_sigma_I -1 _refine.pdbx_ls_sigma_F -1 _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 62.01 _refine.ls_d_res_high 2.20 _refine.ls_percent_reflns_obs 98.54 _refine.ls_R_factor_obs 0.20013 _refine.ls_R_factor_all 0.20013 _refine.ls_R_factor_R_work 0.19727 _refine.ls_R_factor_R_free 0.25367 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.1 _refine.ls_number_reflns_R_free 2377 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_max 1.00 _refine.occupancy_min 0.50 _refine.correlation_coeff_Fo_to_Fc 0.943 _refine.correlation_coeff_Fo_to_Fc_free 0.910 _refine.B_iso_mean 27.148 _refine.aniso_B[1][1] -0.14 _refine.aniso_B[2][2] 0.70 _refine.aniso_B[3][3] -3.15 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] -3.67 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.40 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model 'PDB ENTRY 1IHP' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.311 _refine.pdbx_overall_ESU_R_Free 0.232 _refine.overall_SU_ML 0.172 _refine.overall_SU_B 6.891 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_max 65.15 _refine.B_iso_min 8.88 _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_overall_phase_error ? _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6772 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 184 _refine_hist.number_atoms_solvent 363 _refine_hist.number_atoms_total 7319 _refine_hist.d_res_high 2.20 _refine_hist.d_res_low 62.01 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.019 0.022 ? 7172 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.861 1.979 ? 9808 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.450 5.000 ? 884 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 36.953 24.180 ? 323 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 16.407 15.000 ? 1079 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 16.858 15.000 ? 38 'X-RAY DIFFRACTION' ? r_chiral_restr 0.125 0.200 ? 1107 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.009 0.021 ? 5488 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.906 1.500 ? 4379 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 1.667 2.000 ? 7097 'X-RAY DIFFRACTION' ? r_scbond_it 2.516 3.000 ? 2793 'X-RAY DIFFRACTION' ? r_scangle_it 3.887 4.500 ? 2706 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_restr_ncs.pdbx_refine_id _refine_ls_restr_ncs.pdbx_ens_id _refine_ls_restr_ncs.dom_id _refine_ls_restr_ncs.pdbx_type _refine_ls_restr_ncs.pdbx_auth_asym_id _refine_ls_restr_ncs.pdbx_number _refine_ls_restr_ncs.rms_dev_position _refine_ls_restr_ncs.weight_position _refine_ls_restr_ncs.pdbx_ordinal _refine_ls_restr_ncs.ncs_model_details _refine_ls_restr_ncs.rms_dev_B_iso _refine_ls_restr_ncs.weight_B_iso 'X-RAY DIFFRACTION' 1 1 'TIGHT POSITIONAL' A 231 0.070 0.050 1 ? ? ? 'X-RAY DIFFRACTION' 1 1 'TIGHT THERMAL' A 231 0.170 0.500 2 ? ? ? 'X-RAY DIFFRACTION' 2 1 'TIGHT POSITIONAL' A 1761 0.050 0.050 3 ? ? ? 'X-RAY DIFFRACTION' 2 1 'TIGHT THERMAL' A 1761 0.200 0.500 4 ? ? ? 'X-RAY DIFFRACTION' 3 1 'TIGHT POSITIONAL' A 1365 0.050 0.050 5 ? ? ? 'X-RAY DIFFRACTION' 3 1 'TIGHT THERMAL' A 1365 0.180 0.500 6 ? ? ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.200 _refine_ls_shell.d_res_low 2.257 _refine_ls_shell.number_reflns_R_work 3218 _refine_ls_shell.R_factor_R_work 0.263 _refine_ls_shell.percent_reflns_obs 97.90 _refine_ls_shell.R_factor_R_free 0.335 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 185 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _struct_ncs_dom.pdbx_ens_id _struct_ncs_dom.id _struct_ncs_dom.details 1 1 A 1 2 B 2 1 A 2 2 B 3 1 A 3 2 B # loop_ _struct_ncs_dom_lim.pdbx_ens_id _struct_ncs_dom_lim.dom_id _struct_ncs_dom_lim.pdbx_component_id _struct_ncs_dom_lim.pdbx_refine_code _struct_ncs_dom_lim.beg_auth_asym_id _struct_ncs_dom_lim.beg_auth_seq_id _struct_ncs_dom_lim.end_auth_asym_id _struct_ncs_dom_lim.end_auth_seq_id _struct_ncs_dom_lim.selection_details _struct_ncs_dom_lim.beg_label_asym_id _struct_ncs_dom_lim.beg_label_comp_id _struct_ncs_dom_lim.beg_label_seq_id _struct_ncs_dom_lim.beg_label_alt_id _struct_ncs_dom_lim.end_label_asym_id _struct_ncs_dom_lim.end_label_comp_id _struct_ncs_dom_lim.end_label_seq_id _struct_ncs_dom_lim.end_label_alt_id 1 1 1 1 A 7 A 35 ? . . . . . . . . 1 2 1 1 B 7 B 35 ? . . . . . . . . 2 1 1 1 A 37 A 264 ? . . . . . . . . 2 2 1 1 B 37 B 264 ? . . . . . . . . 3 1 1 1 A 266 A 443 ? . . . . . . . . 3 2 1 1 B 266 B 443 ? . . . . . . . . # loop_ _struct_ncs_ens.id _struct_ncs_ens.details 1 ? 2 ? 3 ? # _struct.entry_id 3K4Q _struct.title 'Aspergillus niger Phytase in complex with myo-inositol hexakis sulfate' _struct.pdbx_descriptor '3-phytase A (E.C.3.1.3.8)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag N _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3K4Q _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text ;Phytase, PhyA, 3-Phosphotase, myo-inositol hexakis phosphate phosphohydrolase, 37288-11-2, myo-Inositol hexakis sulfate, 70701-62-1, Disulfide bond, Glycoprotein, Hydrolase, Secreted ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 2 ? I N N 3 ? J N N 3 ? K N N 3 ? L N N 3 ? M N N 4 ? N N N 4 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 PHE A 18 ? HIS A 23 ? PHE A 18 HIS A 23 1 ? 6 HELX_P HELX_P2 2 LEU A 24 ? ALA A 29 ? LEU A 24 ALA A 29 5 ? 6 HELX_P HELX_P3 3 LEU A 34 ? SER A 38 ? LEU A 34 SER A 38 5 ? 5 HELX_P HELX_P4 4 THR A 65 ? ALA A 83 ? THR A 65 ALA A 83 1 ? 19 HELX_P HELX_P5 5 ASP A 87 ? THR A 95 ? ASP A 87 THR A 95 5 ? 9 HELX_P HELX_P6 6 THR A 106 ? TYR A 124 ? THR A 106 TYR A 124 1 ? 19 HELX_P HELX_P7 7 TYR A 124 ? ARG A 129 ? TYR A 124 ARG A 129 1 ? 6 HELX_P HELX_P8 8 SER A 140 ? LYS A 160 ? SER A 140 LYS A 160 1 ? 21 HELX_P HELX_P9 9 CYS A 192 ? SER A 198 ? CYS A 192 SER A 198 1 ? 7 HELX_P HELX_P10 10 GLU A 199 ? ALA A 210 ? GLU A 199 ALA A 210 1 ? 12 HELX_P HELX_P11 11 PHE A 212 ? LEU A 224 ? PHE A 212 LEU A 224 1 ? 13 HELX_P HELX_P12 12 THR A 230 ? ILE A 246 ? THR A 230 ILE A 246 1 ? 17 HELX_P HELX_P13 13 THR A 248 ? THR A 253 ? THR A 248 THR A 253 5 ? 6 HELX_P HELX_P14 14 SER A 256 ? PHE A 262 ? SER A 256 PHE A 262 5 ? 7 HELX_P HELX_P15 15 THR A 263 ? HIS A 282 ? THR A 263 HIS A 282 1 ? 20 HELX_P HELX_P16 16 GLY A 289 ? GLN A 292 ? GLY A 289 GLN A 292 5 ? 4 HELX_P HELX_P17 17 GLY A 293 ? HIS A 306 ? GLY A 293 HIS A 306 1 ? 14 HELX_P HELX_P18 18 ASN A 316 ? SER A 321 ? ASN A 316 SER A 321 1 ? 6 HELX_P HELX_P19 19 HIS A 338 ? LEU A 349 ? HIS A 338 LEU A 349 1 ? 12 HELX_P HELX_P20 20 SER A 373 ? VAL A 378 ? SER A 373 VAL A 378 1 ? 6 HELX_P HELX_P21 21 ARG A 423 ? LEU A 430 ? ARG A 423 LEU A 430 1 ? 8 HELX_P HELX_P22 22 LEU A 430 ? SER A 435 ? LEU A 430 SER A 435 1 ? 6 HELX_P HELX_P23 23 ASP A 438 ? PHE A 443 ? ASP A 438 PHE A 443 5 ? 6 HELX_P HELX_P24 24 PHE B 18 ? HIS B 23 ? PHE B 18 HIS B 23 1 ? 6 HELX_P HELX_P25 25 LEU B 24 ? ALA B 29 ? LEU B 24 ALA B 29 5 ? 6 HELX_P HELX_P26 26 LEU B 34 ? SER B 38 ? LEU B 34 SER B 38 5 ? 5 HELX_P HELX_P27 27 THR B 65 ? ALA B 83 ? THR B 65 ALA B 83 1 ? 19 HELX_P HELX_P28 28 ASP B 87 ? THR B 95 ? ASP B 87 THR B 95 5 ? 9 HELX_P HELX_P29 29 THR B 106 ? TYR B 124 ? THR B 106 TYR B 124 1 ? 19 HELX_P HELX_P30 30 TYR B 124 ? ARG B 129 ? TYR B 124 ARG B 129 1 ? 6 HELX_P HELX_P31 31 SER B 140 ? LYS B 160 ? SER B 140 LYS B 160 1 ? 21 HELX_P HELX_P32 32 CYS B 192 ? SER B 198 ? CYS B 192 SER B 198 1 ? 7 HELX_P HELX_P33 33 GLU B 199 ? ALA B 210 ? GLU B 199 ALA B 210 1 ? 12 HELX_P HELX_P34 34 PHE B 212 ? LEU B 224 ? PHE B 212 LEU B 224 1 ? 13 HELX_P HELX_P35 35 THR B 230 ? SER B 247 ? THR B 230 SER B 247 1 ? 18 HELX_P HELX_P36 36 THR B 248 ? THR B 253 ? THR B 248 THR B 253 5 ? 6 HELX_P HELX_P37 37 SER B 256 ? PHE B 262 ? SER B 256 PHE B 262 5 ? 7 HELX_P HELX_P38 38 THR B 263 ? HIS B 282 ? THR B 263 HIS B 282 1 ? 20 HELX_P HELX_P39 39 GLY B 289 ? GLN B 292 ? GLY B 289 GLN B 292 5 ? 4 HELX_P HELX_P40 40 GLY B 293 ? HIS B 306 ? GLY B 293 HIS B 306 1 ? 14 HELX_P HELX_P41 41 ASN B 316 ? SER B 321 ? ASN B 316 SER B 321 1 ? 6 HELX_P HELX_P42 42 HIS B 338 ? LEU B 349 ? HIS B 338 LEU B 349 1 ? 12 HELX_P HELX_P43 43 SER B 373 ? VAL B 378 ? SER B 373 VAL B 378 1 ? 6 HELX_P HELX_P44 44 ARG B 423 ? LEU B 430 ? ARG B 423 LEU B 430 1 ? 8 HELX_P HELX_P45 45 LEU B 430 ? SER B 435 ? LEU B 430 SER B 435 1 ? 6 HELX_P HELX_P46 46 ASP B 438 ? PHE B 443 ? ASP B 438 PHE B 443 5 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 8 SG ? ? ? 1_555 A CYS 17 SG ? ? A CYS 8 A CYS 17 1_555 ? ? ? ? ? ? ? 2.028 ? disulf2 disulf ? ? A CYS 48 SG ? ? ? 1_555 A CYS 391 SG ? ? A CYS 48 A CYS 391 1_555 ? ? ? ? ? ? ? 2.080 ? disulf3 disulf ? ? A CYS 192 SG ? ? ? 1_555 A CYS 442 SG ? ? A CYS 192 A CYS 442 1_555 ? ? ? ? ? ? ? 2.008 ? disulf4 disulf ? ? A CYS 241 SG ? ? ? 1_555 A CYS 259 SG ? ? A CYS 241 A CYS 259 1_555 ? ? ? ? ? ? ? 2.024 ? disulf5 disulf ? ? A CYS 413 SG ? ? ? 1_555 A CYS 421 SG ? ? A CYS 413 A CYS 421 1_555 ? ? ? ? ? ? ? 2.057 ? disulf6 disulf ? ? B CYS 8 SG ? ? ? 1_555 B CYS 17 SG ? ? B CYS 8 B CYS 17 1_555 ? ? ? ? ? ? ? 2.034 ? disulf7 disulf ? ? B CYS 48 SG ? ? ? 1_555 B CYS 391 SG ? ? B CYS 48 B CYS 391 1_555 ? ? ? ? ? ? ? 2.065 ? disulf8 disulf ? ? B CYS 192 SG ? ? ? 1_555 B CYS 442 SG ? ? B CYS 192 B CYS 442 1_555 ? ? ? ? ? ? ? 2.030 ? disulf9 disulf ? ? B CYS 241 SG ? ? ? 1_555 B CYS 259 SG ? ? B CYS 241 B CYS 259 1_555 ? ? ? ? ? ? ? 2.053 ? disulf10 disulf ? ? B CYS 413 SG ? ? ? 1_555 B CYS 421 SG ? ? B CYS 413 B CYS 421 1_555 ? ? ? ? ? ? ? 2.058 ? covale1 covale ? ? A ASN 82 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 82 A NAG 1082 1_555 ? ? ? ? ? ? ? 1.447 ? covale2 covale ? ? A ASN 184 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 184 A NAG 1184 1_555 ? ? ? ? ? ? ? 1.424 ? covale3 covale ? ? A ASN 316 ND2 ? ? ? 1_555 F NAG . C1 ? ? A ASN 316 A NAG 1316 1_555 ? ? ? ? ? ? ? 1.438 ? covale4 covale ? ? A ASN 353 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 353 A NAG 1353 1_555 ? ? ? ? ? ? ? 1.401 ? covale5 covale ? ? B ASN 82 ND2 ? ? ? 1_555 I NAG . C1 ? ? B ASN 82 B NAG 1082 1_555 ? ? ? ? ? ? ? 1.423 ? covale6 covale ? ? B ASN 184 ND2 ? ? ? 1_555 J NAG . C1 ? ? B ASN 184 B NAG 1184 1_555 ? ? ? ? ? ? ? 1.463 ? covale7 covale ? ? B ASN 316 ND2 ? ? ? 1_555 K NAG . C1 ? ? B ASN 316 B NAG 1316 1_555 ? ? ? ? ? ? ? 1.449 ? covale8 covale ? ? B ASN 353 ND2 ? ? ? 1_555 L NAG . C1 ? ? B ASN 353 B NAG 1353 1_555 ? ? ? ? ? ? ? 1.421 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 7 ? C ? 7 ? D ? 2 ? E ? 7 ? F ? 7 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? parallel B 2 3 ? parallel B 3 4 ? parallel B 4 5 ? anti-parallel B 5 6 ? anti-parallel B 6 7 ? anti-parallel C 1 2 ? parallel C 2 3 ? parallel C 3 4 ? parallel C 4 5 ? anti-parallel C 5 6 ? anti-parallel C 6 7 ? anti-parallel D 1 2 ? anti-parallel E 1 2 ? parallel E 2 3 ? parallel E 3 4 ? parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel E 6 7 ? anti-parallel F 1 2 ? parallel F 2 3 ? parallel F 3 4 ? parallel F 4 5 ? anti-parallel F 5 6 ? anti-parallel F 6 7 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ASP A 9 ? THR A 10 ? ASP A 9 THR A 10 A 2 GLY A 14 ? TYR A 15 ? GLY A 14 TYR A 15 B 1 VAL A 175 ? SER A 178 ? VAL A 175 SER A 178 B 2 PHE A 134 ? GLY A 139 ? PHE A 134 GLY A 139 B 3 LEU A 332 ? SER A 337 ? LEU A 332 SER A 337 B 4 CYS A 48 ? ARG A 58 ? CYS A 48 ARG A 58 B 5 ARG A 383 ? CYS A 391 ? ARG A 383 CYS A 391 B 6 LEU A 398 ? VAL A 403 ? LEU A 398 VAL A 403 B 7 ARG A 406 ? VAL A 407 ? ARG A 406 VAL A 407 C 1 VAL A 175 ? SER A 178 ? VAL A 175 SER A 178 C 2 PHE A 134 ? GLY A 139 ? PHE A 134 GLY A 139 C 3 LEU A 332 ? SER A 337 ? LEU A 332 SER A 337 C 4 CYS A 48 ? ARG A 58 ? CYS A 48 ARG A 58 C 5 ARG A 383 ? CYS A 391 ? ARG A 383 CYS A 391 C 6 LEU A 398 ? VAL A 403 ? LEU A 398 VAL A 403 C 7 CYS A 421 ? THR A 422 ? CYS A 421 THR A 422 D 1 ASP B 9 ? THR B 10 ? ASP B 9 THR B 10 D 2 GLY B 14 ? TYR B 15 ? GLY B 14 TYR B 15 E 1 VAL B 175 ? ILE B 177 ? VAL B 175 ILE B 177 E 2 PHE B 134 ? SER B 138 ? PHE B 134 SER B 138 E 3 LEU B 332 ? SER B 337 ? LEU B 332 SER B 337 E 4 ARG B 49 ? ARG B 58 ? ARG B 49 ARG B 58 E 5 ARG B 383 ? GLN B 390 ? ARG B 383 GLN B 390 E 6 LEU B 398 ? VAL B 403 ? LEU B 398 VAL B 403 E 7 ARG B 406 ? VAL B 407 ? ARG B 406 VAL B 407 F 1 VAL B 175 ? ILE B 177 ? VAL B 175 ILE B 177 F 2 PHE B 134 ? SER B 138 ? PHE B 134 SER B 138 F 3 LEU B 332 ? SER B 337 ? LEU B 332 SER B 337 F 4 ARG B 49 ? ARG B 58 ? ARG B 49 ARG B 58 F 5 ARG B 383 ? GLN B 390 ? ARG B 383 GLN B 390 F 6 LEU B 398 ? VAL B 403 ? LEU B 398 VAL B 403 F 7 CYS B 421 ? THR B 422 ? CYS B 421 THR B 422 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N THR A 10 ? N THR A 10 O GLY A 14 ? O GLY A 14 B 1 2 O ILE A 177 ? O ILE A 177 N GLY A 139 ? N GLY A 139 B 2 3 N ARG A 136 ? N ARG A 136 O ALA A 334 ? O ALA A 334 B 3 4 O ASP A 335 ? O ASP A 335 N SER A 57 ? N SER A 57 B 4 5 N ARG A 49 ? N ARG A 49 O GLN A 390 ? O GLN A 390 B 5 6 N GLU A 387 ? N GLU A 387 O ARG A 400 ? O ARG A 400 B 6 7 N VAL A 403 ? N VAL A 403 O ARG A 406 ? O ARG A 406 C 1 2 O ILE A 177 ? O ILE A 177 N GLY A 139 ? N GLY A 139 C 2 3 N ARG A 136 ? N ARG A 136 O ALA A 334 ? O ALA A 334 C 3 4 O ASP A 335 ? O ASP A 335 N SER A 57 ? N SER A 57 C 4 5 N ARG A 49 ? N ARG A 49 O GLN A 390 ? O GLN A 390 C 5 6 N GLU A 387 ? N GLU A 387 O ARG A 400 ? O ARG A 400 C 6 7 N VAL A 399 ? N VAL A 399 O CYS A 421 ? O CYS A 421 D 1 2 N THR B 10 ? N THR B 10 O GLY B 14 ? O GLY B 14 E 1 2 O ILE B 177 ? O ILE B 177 N SER B 137 ? N SER B 137 E 2 3 N ARG B 136 ? N ARG B 136 O ALA B 334 ? O ALA B 334 E 3 4 O ASP B 335 ? O ASP B 335 N SER B 57 ? N SER B 57 E 4 5 N ARG B 49 ? N ARG B 49 O GLN B 390 ? O GLN B 390 E 5 6 N GLU B 387 ? N GLU B 387 O ARG B 400 ? O ARG B 400 E 6 7 N VAL B 403 ? N VAL B 403 O ARG B 406 ? O ARG B 406 F 1 2 O ILE B 177 ? O ILE B 177 N SER B 137 ? N SER B 137 F 2 3 N ARG B 136 ? N ARG B 136 O ALA B 334 ? O ALA B 334 F 3 4 O ASP B 335 ? O ASP B 335 N SER B 57 ? N SER B 57 F 4 5 N ARG B 49 ? N ARG B 49 O GLN B 390 ? O GLN B 390 F 5 6 N GLU B 387 ? N GLU B 387 O ARG B 400 ? O ARG B 400 F 6 7 N VAL B 399 ? N VAL B 399 O CYS B 421 ? O CYS B 421 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 14 'BINDING SITE FOR RESIDUE IHS A 500' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 1082' AC3 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG A 1184' AC4 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE NAG A 1316' AC5 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG A 1353' AC6 Software ? ? ? ? 11 'BINDING SITE FOR RESIDUE IHS B 500' AC7 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 1082' AC8 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B 1184' AC9 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NAG B 1316' BC1 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG B 1353' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 14 GLN A 27 ? GLN A 27 . ? 1_555 ? 2 AC1 14 TYR A 28 ? TYR A 28 . ? 1_555 ? 3 AC1 14 ARG A 58 ? ARG A 58 . ? 1_555 ? 4 AC1 14 HIS A 59 ? HIS A 59 . ? 1_555 ? 5 AC1 14 ARG A 62 ? ARG A 62 . ? 1_555 ? 6 AC1 14 THR A 65 ? THR A 65 . ? 1_555 ? 7 AC1 14 LYS A 68 ? LYS A 68 . ? 1_555 ? 8 AC1 14 ARG A 142 ? ARG A 142 . ? 1_555 ? 9 AC1 14 ASP A 188 ? ASP A 188 . ? 1_555 ? 10 AC1 14 LYS A 278 ? LYS A 278 . ? 1_555 ? 11 AC1 14 HIS A 338 ? HIS A 338 . ? 1_555 ? 12 AC1 14 ASP A 339 ? ASP A 339 . ? 1_555 ? 13 AC1 14 HOH M . ? HOH A 572 . ? 1_555 ? 14 AC1 14 HOH M . ? HOH A 617 . ? 1_555 ? 15 AC2 5 GLU A 78 ? GLU A 78 . ? 1_555 ? 16 AC2 5 ASN A 82 ? ASN A 82 . ? 1_555 ? 17 AC2 5 VAL A 227 ? VAL A 227 . ? 1_555 ? 18 AC2 5 THR A 228 ? THR A 228 . ? 1_555 ? 19 AC2 5 HOH M . ? HOH A 468 . ? 1_555 ? 20 AC3 8 ASN A 184 ? ASN A 184 . ? 1_555 ? 21 AC3 8 ASP A 312 ? ASP A 312 . ? 1_555 ? 22 AC3 8 THR A 313 ? THR A 313 . ? 1_555 ? 23 AC3 8 SER A 315 ? SER A 315 . ? 1_555 ? 24 AC3 8 ASN A 316 ? ASN A 316 . ? 1_555 ? 25 AC3 8 HIS A 317 ? HIS A 317 . ? 1_555 ? 26 AC3 8 TRP A 439 ? TRP A 439 . ? 1_555 ? 27 AC3 8 NAG F . ? NAG A 1316 . ? 1_555 ? 28 AC4 9 SER A 182 ? SER A 182 . ? 1_555 ? 29 AC4 9 SER A 183 ? SER A 183 . ? 1_555 ? 30 AC4 9 ASN A 184 ? ASN A 184 . ? 1_555 ? 31 AC4 9 ASN A 316 ? ASN A 316 . ? 1_555 ? 32 AC4 9 LEU A 319 ? LEU A 319 . ? 1_555 ? 33 AC4 9 HOH M . ? HOH A 463 . ? 1_555 ? 34 AC4 9 HOH M . ? HOH A 591 . ? 1_555 ? 35 AC4 9 HOH M . ? HOH A 597 . ? 1_555 ? 36 AC4 9 NAG E . ? NAG A 1184 . ? 1_555 ? 37 AC5 10 ASN A 353 ? ASN A 353 . ? 1_555 ? 38 AC5 10 HIS A 411 ? HIS A 411 . ? 1_555 ? 39 AC5 10 GLY A 412 ? GLY A 412 . ? 1_555 ? 40 AC5 10 GLY A 429 ? GLY A 429 . ? 1_555 ? 41 AC5 10 PHE A 432 ? PHE A 432 . ? 1_555 ? 42 AC5 10 HOH M . ? HOH A 574 . ? 1_555 ? 43 AC5 10 HOH M . ? HOH A 603 . ? 1_555 ? 44 AC5 10 ASN B 130 ? ASN B 130 . ? 1_556 ? 45 AC5 10 ARG B 163 ? ARG B 163 . ? 1_556 ? 46 AC5 10 GLN B 165 ? GLN B 165 . ? 1_556 ? 47 AC6 11 GLN B 27 ? GLN B 27 . ? 1_555 ? 48 AC6 11 TYR B 28 ? TYR B 28 . ? 1_555 ? 49 AC6 11 ARG B 58 ? ARG B 58 . ? 1_555 ? 50 AC6 11 HIS B 59 ? HIS B 59 . ? 1_555 ? 51 AC6 11 ARG B 62 ? ARG B 62 . ? 1_555 ? 52 AC6 11 THR B 65 ? THR B 65 . ? 1_555 ? 53 AC6 11 LYS B 68 ? LYS B 68 . ? 1_555 ? 54 AC6 11 ARG B 142 ? ARG B 142 . ? 1_555 ? 55 AC6 11 LYS B 278 ? LYS B 278 . ? 1_555 ? 56 AC6 11 HIS B 338 ? HIS B 338 . ? 1_555 ? 57 AC6 11 ASP B 339 ? ASP B 339 . ? 1_555 ? 58 AC7 5 GLU B 78 ? GLU B 78 . ? 1_555 ? 59 AC7 5 ASN B 82 ? ASN B 82 . ? 1_555 ? 60 AC7 5 VAL B 227 ? VAL B 227 . ? 1_555 ? 61 AC7 5 THR B 228 ? THR B 228 . ? 1_555 ? 62 AC7 5 HOH N . ? HOH B 480 . ? 1_555 ? 63 AC8 6 ASN B 184 ? ASN B 184 . ? 1_555 ? 64 AC8 6 ASP B 312 ? ASP B 312 . ? 1_555 ? 65 AC8 6 SER B 315 ? SER B 315 . ? 1_555 ? 66 AC8 6 ASN B 316 ? ASN B 316 . ? 1_555 ? 67 AC8 6 HIS B 317 ? HIS B 317 . ? 1_555 ? 68 AC8 6 NAG K . ? NAG B 1316 . ? 1_555 ? 69 AC9 7 SER B 182 ? SER B 182 . ? 1_555 ? 70 AC9 7 SER B 183 ? SER B 183 . ? 1_555 ? 71 AC9 7 ASN B 184 ? ASN B 184 . ? 1_555 ? 72 AC9 7 ASN B 316 ? ASN B 316 . ? 1_555 ? 73 AC9 7 LEU B 319 ? LEU B 319 . ? 1_555 ? 74 AC9 7 HOH N . ? HOH B 574 . ? 1_555 ? 75 AC9 7 NAG J . ? NAG B 1184 . ? 1_555 ? 76 BC1 10 ASN A 130 ? ASN A 130 . ? 1_655 ? 77 BC1 10 ARG A 163 ? ARG A 163 . ? 1_655 ? 78 BC1 10 GLN A 165 ? GLN A 165 . ? 1_655 ? 79 BC1 10 ASN B 353 ? ASN B 353 . ? 1_555 ? 80 BC1 10 HIS B 411 ? HIS B 411 . ? 1_555 ? 81 BC1 10 GLY B 412 ? GLY B 412 . ? 1_555 ? 82 BC1 10 GLY B 429 ? GLY B 429 . ? 1_555 ? 83 BC1 10 PHE B 432 ? PHE B 432 . ? 1_555 ? 84 BC1 10 HOH N . ? HOH B 450 . ? 1_555 ? 85 BC1 10 HOH N . ? HOH B 535 . ? 1_555 ? # _database_PDB_matrix.entry_id 3K4Q _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3K4Q _atom_sites.fract_transf_matrix[1][1] 0.014144 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.005319 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.011419 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.013066 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 7 ? 2.807 -0.724 8.425 1.00 45.57 ? 7 SER A N 1 ATOM 2 C CA . SER A 1 7 ? 3.014 -2.204 8.608 1.00 45.38 ? 7 SER A CA 1 ATOM 3 C C . SER A 1 7 ? 3.208 -2.699 10.052 1.00 44.42 ? 7 SER A C 1 ATOM 4 O O . SER A 1 7 ? 2.665 -3.754 10.392 1.00 44.91 ? 7 SER A O 1 ATOM 5 C CB . SER A 1 7 ? 4.127 -2.818 7.733 1.00 45.81 ? 7 SER A CB 1 ATOM 6 O OG . SER A 1 7 ? 5.223 -1.971 7.458 1.00 48.31 ? 7 SER A OG 1 ATOM 7 N N . CYS A 1 8 ? 3.993 -2.002 10.889 1.00 42.10 ? 8 CYS A N 1 ATOM 8 C CA . CYS A 1 8 ? 4.149 -2.443 12.299 1.00 40.06 ? 8 CYS A CA 1 ATOM 9 C C . CYS A 1 8 ? 2.972 -1.923 13.167 1.00 37.86 ? 8 CYS A C 1 ATOM 10 O O . CYS A 1 8 ? 2.786 -2.332 14.302 1.00 37.59 ? 8 CYS A O 1 ATOM 11 C CB . CYS A 1 8 ? 5.527 -2.049 12.872 1.00 39.74 ? 8 CYS A CB 1 ATOM 12 S SG . CYS A 1 8 ? 5.903 -0.228 12.858 1.00 41.23 ? 8 CYS A SG 1 ATOM 13 N N . ASP A 1 9 ? 2.174 -1.042 12.593 1.00 35.45 ? 9 ASP A N 1 ATOM 14 C CA . ASP A 1 9 ? 1.043 -0.451 13.255 1.00 34.39 ? 9 ASP A CA 1 ATOM 15 C C . ASP A 1 9 ? -0.203 -0.719 12.398 1.00 33.87 ? 9 ASP A C 1 ATOM 16 O O . ASP A 1 9 ? -0.325 -0.141 11.307 1.00 34.11 ? 9 ASP A O 1 ATOM 17 C CB . ASP A 1 9 ? 1.296 1.058 13.393 1.00 33.88 ? 9 ASP A CB 1 ATOM 18 C CG . ASP A 1 9 ? 0.213 1.790 14.197 1.00 33.00 ? 9 ASP A CG 1 ATOM 19 O OD1 . ASP A 1 9 ? -0.585 1.137 14.881 1.00 33.19 ? 9 ASP A OD1 1 ATOM 20 O OD2 . ASP A 1 9 ? 0.180 3.043 14.165 1.00 33.72 ? 9 ASP A OD2 1 ATOM 21 N N . THR A 1 10 ? -1.123 -1.552 12.894 1.00 31.83 ? 10 THR A N 1 ATOM 22 C CA . THR A 1 10 ? -2.302 -1.963 12.140 1.00 31.14 ? 10 THR A CA 1 ATOM 23 C C . THR A 1 10 ? -3.633 -1.892 12.935 1.00 30.38 ? 10 THR A C 1 ATOM 24 O O . THR A 1 10 ? -3.657 -1.738 14.154 1.00 29.09 ? 10 THR A O 1 ATOM 25 C CB . THR A 1 10 ? -2.141 -3.402 11.636 1.00 31.53 ? 10 THR A CB 1 ATOM 26 O OG1 . THR A 1 10 ? -1.922 -4.283 12.750 1.00 30.80 ? 10 THR A OG1 1 ATOM 27 C CG2 . THR A 1 10 ? -0.934 -3.478 10.671 1.00 31.64 ? 10 THR A CG2 1 ATOM 28 N N . VAL A 1 11 ? -4.749 -1.986 12.241 1.00 28.96 ? 11 VAL A N 1 ATOM 29 C CA . VAL A 1 11 ? -6.018 -2.046 12.936 1.00 29.03 ? 11 VAL A CA 1 ATOM 30 C C . VAL A 1 11 ? -6.017 -3.292 13.837 1.00 29.53 ? 11 VAL A C 1 ATOM 31 O O . VAL A 1 11 ? -6.452 -3.238 14.992 1.00 29.42 ? 11 VAL A O 1 ATOM 32 C CB . VAL A 1 11 ? -7.215 -2.054 11.948 1.00 29.03 ? 11 VAL A CB 1 ATOM 33 C CG1 . VAL A 1 11 ? -8.509 -2.446 12.625 1.00 26.48 ? 11 VAL A CG1 1 ATOM 34 C CG2 . VAL A 1 11 ? -7.320 -0.671 11.261 1.00 28.99 ? 11 VAL A CG2 1 ATOM 35 N N . ASP A 1 12 ? -5.483 -4.391 13.330 1.00 29.54 ? 12 ASP A N 1 ATOM 36 C CA . ASP A 1 12 ? -5.756 -5.641 13.960 1.00 31.18 ? 12 ASP A CA 1 ATOM 37 C C . ASP A 1 12 ? -4.788 -6.004 15.082 1.00 31.15 ? 12 ASP A C 1 ATOM 38 O O . ASP A 1 12 ? -5.201 -6.598 16.089 1.00 29.96 ? 12 ASP A O 1 ATOM 39 C CB . ASP A 1 12 ? -5.785 -6.755 12.930 1.00 32.45 ? 12 ASP A CB 1 ATOM 40 C CG . ASP A 1 12 ? -7.114 -7.460 12.927 1.00 37.69 ? 12 ASP A CG 1 ATOM 41 O OD1 . ASP A 1 12 ? -7.300 -8.350 13.842 1.00 38.17 ? 12 ASP A OD1 1 ATOM 42 O OD2 . ASP A 1 12 ? -7.966 -7.092 12.038 1.00 38.48 ? 12 ASP A OD2 1 ATOM 43 N N . GLN A 1 13 ? -3.515 -5.651 14.882 1.00 30.35 ? 13 GLN A N 1 ATOM 44 C CA . GLN A 1 13 ? -2.450 -6.019 15.796 1.00 30.45 ? 13 GLN A CA 1 ATOM 45 C C . GLN A 1 13 ? -2.003 -4.818 16.646 1.00 29.87 ? 13 GLN A C 1 ATOM 46 O O . GLN A 1 13 ? -1.257 -4.988 17.611 1.00 30.25 ? 13 GLN A O 1 ATOM 47 C CB . GLN A 1 13 ? -1.285 -6.659 15.021 1.00 31.09 ? 13 GLN A CB 1 ATOM 48 C CG . GLN A 1 13 ? -1.610 -8.084 14.579 1.00 34.17 ? 13 GLN A CG 1 ATOM 49 C CD . GLN A 1 13 ? -1.845 -8.966 15.767 1.00 40.07 ? 13 GLN A CD 1 ATOM 50 O OE1 . GLN A 1 13 ? -0.901 -9.249 16.520 1.00 44.11 ? 13 GLN A OE1 1 ATOM 51 N NE2 . GLN A 1 13 ? -3.109 -9.389 15.982 1.00 40.75 ? 13 GLN A NE2 1 ATOM 52 N N . GLY A 1 14 ? -2.500 -3.628 16.317 1.00 28.76 ? 14 GLY A N 1 ATOM 53 C CA . GLY A 1 14 ? -2.247 -2.429 17.101 1.00 28.26 ? 14 GLY A CA 1 ATOM 54 C C . GLY A 1 14 ? -0.824 -1.994 16.823 1.00 28.99 ? 14 GLY A C 1 ATOM 55 O O . GLY A 1 14 ? -0.338 -2.181 15.708 1.00 28.79 ? 14 GLY A O 1 ATOM 56 N N . TYR A 1 15 ? -0.145 -1.471 17.847 1.00 28.26 ? 15 TYR A N 1 ATOM 57 C CA . TYR A 1 15 ? 1.141 -0.841 17.701 1.00 28.40 ? 15 TYR A CA 1 ATOM 58 C C . TYR A 1 15 ? 2.273 -1.798 18.031 1.00 29.31 ? 15 TYR A C 1 ATOM 59 O O . TYR A 1 15 ? 2.637 -1.959 19.187 1.00 30.08 ? 15 TYR A O 1 ATOM 60 C CB . TYR A 1 15 ? 1.191 0.358 18.615 1.00 27.43 ? 15 TYR A CB 1 ATOM 61 C CG . TYR A 1 15 ? 2.407 1.219 18.419 1.00 28.36 ? 15 TYR A CG 1 ATOM 62 C CD1 . TYR A 1 15 ? 2.425 2.211 17.440 1.00 27.15 ? 15 TYR A CD1 1 ATOM 63 C CD2 . TYR A 1 15 ? 3.540 1.066 19.233 1.00 28.47 ? 15 TYR A CD2 1 ATOM 64 C CE1 . TYR A 1 15 ? 3.509 3.023 17.279 1.00 27.02 ? 15 TYR A CE1 1 ATOM 65 C CE2 . TYR A 1 15 ? 4.657 1.874 19.060 1.00 27.81 ? 15 TYR A CE2 1 ATOM 66 C CZ . TYR A 1 15 ? 4.634 2.852 18.106 1.00 28.18 ? 15 TYR A CZ 1 ATOM 67 O OH . TYR A 1 15 ? 5.729 3.660 17.939 1.00 27.27 ? 15 TYR A OH 1 ATOM 68 N N . GLN A 1 16 ? 2.817 -2.449 17.006 1.00 30.87 ? 16 GLN A N 1 ATOM 69 C CA . GLN A 1 16 ? 3.881 -3.454 17.163 1.00 30.89 ? 16 GLN A CA 1 ATOM 70 C C . GLN A 1 16 ? 5.227 -2.847 16.723 1.00 31.91 ? 16 GLN A C 1 ATOM 71 O O . GLN A 1 16 ? 6.166 -3.546 16.433 1.00 32.52 ? 16 GLN A O 1 ATOM 72 C CB . GLN A 1 16 ? 3.540 -4.725 16.369 1.00 30.58 ? 16 GLN A CB 1 ATOM 73 C CG . GLN A 1 16 ? 2.169 -5.305 16.697 1.00 30.46 ? 16 GLN A CG 1 ATOM 74 C CD . GLN A 1 16 ? 2.165 -6.116 17.996 1.00 30.96 ? 16 GLN A CD 1 ATOM 75 O OE1 . GLN A 1 16 ? 3.218 -6.347 18.567 1.00 31.88 ? 16 GLN A OE1 1 ATOM 76 N NE2 . GLN A 1 16 ? 0.985 -6.561 18.454 1.00 26.93 ? 16 GLN A NE2 1 ATOM 77 N N . CYS A 1 17 ? 5.308 -1.532 16.657 1.00 32.87 ? 17 CYS A N 1 ATOM 78 C CA . CYS A 1 17 ? 6.542 -0.899 16.304 1.00 34.32 ? 17 CYS A CA 1 ATOM 79 C C . CYS A 1 17 ? 7.431 -0.815 17.555 1.00 34.43 ? 17 CYS A C 1 ATOM 80 O O . CYS A 1 17 ? 6.937 -0.510 18.634 1.00 34.47 ? 17 CYS A O 1 ATOM 81 C CB . CYS A 1 17 ? 6.259 0.505 15.764 1.00 34.75 ? 17 CYS A CB 1 ATOM 82 S SG . CYS A 1 17 ? 4.945 0.566 14.459 1.00 39.93 ? 17 CYS A SG 1 ATOM 83 N N . PHE A 1 18 ? 8.734 -1.061 17.386 1.00 34.17 ? 18 PHE A N 1 ATOM 84 C CA . PHE A 1 18 ? 9.760 -0.893 18.428 1.00 33.81 ? 18 PHE A CA 1 ATOM 85 C C . PHE A 1 18 ? 9.306 -1.523 19.696 1.00 33.21 ? 18 PHE A C 1 ATOM 86 O O . PHE A 1 18 ? 9.450 -0.919 20.755 1.00 33.61 ? 18 PHE A O 1 ATOM 87 C CB . PHE A 1 18 ? 10.042 0.576 18.745 1.00 33.51 ? 18 PHE A CB 1 ATOM 88 C CG . PHE A 1 18 ? 10.130 1.440 17.555 1.00 35.39 ? 18 PHE A CG 1 ATOM 89 C CD1 . PHE A 1 18 ? 11.282 1.407 16.740 1.00 37.90 ? 18 PHE A CD1 1 ATOM 90 C CD2 . PHE A 1 18 ? 9.082 2.292 17.219 1.00 34.91 ? 18 PHE A CD2 1 ATOM 91 C CE1 . PHE A 1 18 ? 11.376 2.226 15.616 1.00 36.05 ? 18 PHE A CE1 1 ATOM 92 C CE2 . PHE A 1 18 ? 9.173 3.116 16.094 1.00 35.25 ? 18 PHE A CE2 1 ATOM 93 C CZ . PHE A 1 18 ? 10.328 3.075 15.290 1.00 35.46 ? 18 PHE A CZ 1 ATOM 94 N N . SER A 1 19 ? 8.738 -2.715 19.583 1.00 32.74 ? 19 SER A N 1 ATOM 95 C CA . SER A 1 19 ? 7.925 -3.286 20.650 1.00 32.67 ? 19 SER A CA 1 ATOM 96 C C . SER A 1 19 ? 8.749 -3.621 21.903 1.00 32.32 ? 19 SER A C 1 ATOM 97 O O . SER A 1 19 ? 8.192 -3.690 22.999 1.00 31.33 ? 19 SER A O 1 ATOM 98 C CB . SER A 1 19 ? 7.210 -4.506 20.139 1.00 32.49 ? 19 SER A CB 1 ATOM 99 O OG . SER A 1 19 ? 8.176 -5.393 19.674 1.00 34.35 ? 19 SER A OG 1 ATOM 100 N N . GLU A 1 20 ? 10.063 -3.800 21.706 1.00 31.72 ? 20 GLU A N 1 ATOM 101 C CA . GLU A 1 20 ? 11.041 -4.034 22.790 1.00 31.51 ? 20 GLU A CA 1 ATOM 102 C C . GLU A 1 20 ? 11.116 -2.836 23.765 1.00 29.42 ? 20 GLU A C 1 ATOM 103 O O . GLU A 1 20 ? 11.583 -3.001 24.858 1.00 29.49 ? 20 GLU A O 1 ATOM 104 C CB . GLU A 1 20 ? 12.462 -4.395 22.234 1.00 31.58 ? 20 GLU A CB 1 ATOM 105 C CG . GLU A 1 20 ? 13.168 -3.292 21.385 1.00 35.34 ? 20 GLU A CG 1 ATOM 106 C CD . GLU A 1 20 ? 12.683 -3.167 19.890 1.00 40.55 ? 20 GLU A CD 1 ATOM 107 O OE1 . GLU A 1 20 ? 12.130 -4.146 19.309 1.00 39.31 ? 20 GLU A OE1 1 ATOM 108 O OE2 . GLU A 1 20 ? 12.876 -2.058 19.300 1.00 40.99 ? 20 GLU A OE2 1 ATOM 109 N N . THR A 1 21 ? 10.658 -1.658 23.343 1.00 27.53 ? 21 THR A N 1 ATOM 110 C CA . THR A 1 21 ? 10.638 -0.458 24.170 1.00 25.83 ? 21 THR A CA 1 ATOM 111 C C . THR A 1 21 ? 9.181 -0.046 24.404 1.00 25.15 ? 21 THR A C 1 ATOM 112 O O . THR A 1 21 ? 8.745 0.111 25.541 1.00 23.82 ? 21 THR A O 1 ATOM 113 C CB . THR A 1 21 ? 11.431 0.646 23.489 1.00 25.62 ? 21 THR A CB 1 ATOM 114 O OG1 . THR A 1 21 ? 12.798 0.219 23.389 1.00 28.03 ? 21 THR A OG1 1 ATOM 115 C CG2 . THR A 1 21 ? 11.368 1.970 24.258 1.00 25.35 ? 21 THR A CG2 1 ATOM 116 N N . SER A 1 22 ? 8.405 0.037 23.321 1.00 24.01 ? 22 SER A N 1 ATOM 117 C CA . SER A 1 22 ? 7.102 0.675 23.365 1.00 23.76 ? 22 SER A CA 1 ATOM 118 C C . SER A 1 22 ? 6.144 -0.170 24.221 1.00 23.35 ? 22 SER A C 1 ATOM 119 O O . SER A 1 22 ? 5.237 0.338 24.848 1.00 23.27 ? 22 SER A O 1 ATOM 120 C CB . SER A 1 22 ? 6.565 0.836 21.939 1.00 23.24 ? 22 SER A CB 1 ATOM 121 O OG . SER A 1 22 ? 6.262 -0.449 21.383 1.00 23.28 ? 22 SER A OG 1 ATOM 122 N N . HIS A 1 23 ? 6.336 -1.478 24.209 1.00 22.97 ? 23 HIS A N 1 ATOM 123 C CA . HIS A 1 23 ? 5.525 -2.365 25.035 1.00 22.87 ? 23 HIS A CA 1 ATOM 124 C C . HIS A 1 23 ? 5.817 -2.347 26.554 1.00 22.84 ? 23 HIS A C 1 ATOM 125 O O . HIS A 1 23 ? 5.117 -2.990 27.334 1.00 23.62 ? 23 HIS A O 1 ATOM 126 C CB . HIS A 1 23 ? 5.588 -3.777 24.451 1.00 22.32 ? 23 HIS A CB 1 ATOM 127 C CG . HIS A 1 23 ? 4.903 -3.896 23.120 1.00 24.39 ? 23 HIS A CG 1 ATOM 128 N ND1 . HIS A 1 23 ? 4.528 -5.113 22.571 1.00 28.00 ? 23 HIS A ND1 1 ATOM 129 C CD2 . HIS A 1 23 ? 4.547 -2.952 22.215 1.00 24.47 ? 23 HIS A CD2 1 ATOM 130 C CE1 . HIS A 1 23 ? 3.954 -4.913 21.398 1.00 25.68 ? 23 HIS A CE1 1 ATOM 131 N NE2 . HIS A 1 23 ? 3.947 -3.607 21.160 1.00 25.95 ? 23 HIS A NE2 1 ATOM 132 N N . LEU A 1 24 ? 6.825 -1.596 26.980 1.00 22.86 ? 24 LEU A N 1 ATOM 133 C CA . LEU A 1 24 ? 7.137 -1.508 28.390 1.00 22.89 ? 24 LEU A CA 1 ATOM 134 C C . LEU A 1 24 ? 6.844 -0.098 28.901 1.00 22.57 ? 24 LEU A C 1 ATOM 135 O O . LEU A 1 24 ? 7.535 0.382 29.800 1.00 22.65 ? 24 LEU A O 1 ATOM 136 C CB . LEU A 1 24 ? 8.595 -1.904 28.667 1.00 22.95 ? 24 LEU A CB 1 ATOM 137 C CG . LEU A 1 24 ? 9.156 -3.249 28.148 1.00 23.47 ? 24 LEU A CG 1 ATOM 138 C CD1 . LEU A 1 24 ? 10.654 -3.205 28.197 1.00 27.27 ? 24 LEU A CD1 1 ATOM 139 C CD2 . LEU A 1 24 ? 8.646 -4.517 28.837 1.00 20.16 ? 24 LEU A CD2 1 ATOM 140 N N . TRP A 1 25 ? 5.857 0.594 28.328 1.00 20.79 ? 25 TRP A N 1 ATOM 141 C CA . TRP A 1 25 ? 5.572 1.897 28.872 1.00 20.50 ? 25 TRP A CA 1 ATOM 142 C C . TRP A 1 25 ? 4.353 1.849 29.784 1.00 19.77 ? 25 TRP A C 1 ATOM 143 O O . TRP A 1 25 ? 3.781 2.865 30.113 1.00 19.74 ? 25 TRP A O 1 ATOM 144 C CB . TRP A 1 25 ? 5.377 2.915 27.789 1.00 20.37 ? 25 TRP A CB 1 ATOM 145 C CG . TRP A 1 25 ? 6.589 3.195 26.924 1.00 23.26 ? 25 TRP A CG 1 ATOM 146 C CD1 . TRP A 1 25 ? 7.895 3.066 27.269 1.00 22.24 ? 25 TRP A CD1 1 ATOM 147 C CD2 . TRP A 1 25 ? 6.572 3.663 25.563 1.00 24.36 ? 25 TRP A CD2 1 ATOM 148 N NE1 . TRP A 1 25 ? 8.704 3.433 26.210 1.00 24.80 ? 25 TRP A NE1 1 ATOM 149 C CE2 . TRP A 1 25 ? 7.924 3.798 25.151 1.00 24.55 ? 25 TRP A CE2 1 ATOM 150 C CE3 . TRP A 1 25 ? 5.544 3.962 24.649 1.00 21.74 ? 25 TRP A CE3 1 ATOM 151 C CZ2 . TRP A 1 25 ? 8.294 4.219 23.839 1.00 25.09 ? 25 TRP A CZ2 1 ATOM 152 C CZ3 . TRP A 1 25 ? 5.898 4.417 23.370 1.00 22.28 ? 25 TRP A CZ3 1 ATOM 153 C CH2 . TRP A 1 25 ? 7.280 4.545 22.979 1.00 25.27 ? 25 TRP A CH2 1 ATOM 154 N N . GLY A 1 26 ? 3.941 0.660 30.158 1.00 19.64 ? 26 GLY A N 1 ATOM 155 C CA . GLY A 1 26 ? 2.767 0.523 30.995 1.00 20.38 ? 26 GLY A CA 1 ATOM 156 C C . GLY A 1 26 ? 1.513 1.095 30.359 1.00 20.56 ? 26 GLY A C 1 ATOM 157 O O . GLY A 1 26 ? 1.259 0.853 29.160 1.00 20.87 ? 26 GLY A O 1 ATOM 158 N N . GLN A 1 27 ? 0.750 1.851 31.156 1.00 18.99 ? 27 GLN A N 1 ATOM 159 C CA . GLN A 1 27 ? -0.469 2.510 30.729 1.00 18.91 ? 27 GLN A CA 1 ATOM 160 C C . GLN A 1 27 ? -0.169 3.662 29.738 1.00 19.17 ? 27 GLN A C 1 ATOM 161 O O . GLN A 1 27 ? -1.112 4.302 29.206 1.00 19.05 ? 27 GLN A O 1 ATOM 162 C CB . GLN A 1 27 ? -1.319 3.013 31.930 1.00 19.47 ? 27 GLN A CB 1 ATOM 163 C CG . GLN A 1 27 ? -0.806 4.302 32.652 1.00 20.20 ? 27 GLN A CG 1 ATOM 164 C CD . GLN A 1 27 ? 0.484 4.079 33.463 1.00 23.55 ? 27 GLN A CD 1 ATOM 165 O OE1 . GLN A 1 27 ? 0.725 2.978 33.930 1.00 21.87 ? 27 GLN A OE1 1 ATOM 166 N NE2 . GLN A 1 27 ? 1.314 5.115 33.602 1.00 23.28 ? 27 GLN A NE2 1 ATOM 167 N N . TYR A 1 28 ? 1.122 3.928 29.512 1.00 18.02 ? 28 TYR A N 1 ATOM 168 C CA . TYR A 1 28 ? 1.528 4.798 28.410 1.00 19.67 ? 28 TYR A CA 1 ATOM 169 C C . TYR A 1 28 ? 1.913 4.030 27.126 1.00 19.93 ? 28 TYR A C 1 ATOM 170 O O . TYR A 1 28 ? 2.420 4.618 26.201 1.00 20.16 ? 28 TYR A O 1 ATOM 171 C CB . TYR A 1 28 ? 2.690 5.758 28.804 1.00 19.96 ? 28 TYR A CB 1 ATOM 172 C CG . TYR A 1 28 ? 2.436 6.623 30.028 1.00 20.62 ? 28 TYR A CG 1 ATOM 173 C CD1 . TYR A 1 28 ? 1.131 7.109 30.329 1.00 19.63 ? 28 TYR A CD1 1 ATOM 174 C CD2 . TYR A 1 28 ? 3.474 6.931 30.906 1.00 20.90 ? 28 TYR A CD2 1 ATOM 175 C CE1 . TYR A 1 28 ? 0.882 7.914 31.428 1.00 17.85 ? 28 TYR A CE1 1 ATOM 176 C CE2 . TYR A 1 28 ? 3.224 7.739 32.059 1.00 21.13 ? 28 TYR A CE2 1 ATOM 177 C CZ . TYR A 1 28 ? 1.935 8.195 32.316 1.00 20.27 ? 28 TYR A CZ 1 ATOM 178 O OH . TYR A 1 28 ? 1.715 9.000 33.403 1.00 21.29 ? 28 TYR A OH 1 ATOM 179 N N . ALA A 1 29 ? 1.729 2.716 27.119 1.00 20.98 ? 29 ALA A N 1 ATOM 180 C CA . ALA A 1 29 ? 1.932 1.921 25.897 1.00 22.60 ? 29 ALA A CA 1 ATOM 181 C C . ALA A 1 29 ? 0.724 2.127 24.989 1.00 21.83 ? 29 ALA A C 1 ATOM 182 O O . ALA A 1 29 ? -0.442 2.156 25.438 1.00 21.84 ? 29 ALA A O 1 ATOM 183 C CB . ALA A 1 29 ? 2.159 0.433 26.187 1.00 21.70 ? 29 ALA A CB 1 ATOM 184 N N . PRO A 1 30 ? 1.003 2.341 23.720 1.00 22.21 ? 30 PRO A N 1 ATOM 185 C CA . PRO A 1 30 ? -0.116 2.356 22.714 1.00 21.20 ? 30 PRO A CA 1 ATOM 186 C C . PRO A 1 30 ? -0.704 0.942 22.649 1.00 20.16 ? 30 PRO A C 1 ATOM 187 O O . PRO A 1 30 ? 0.058 -0.041 22.794 1.00 19.59 ? 30 PRO A O 1 ATOM 188 C CB . PRO A 1 30 ? 0.587 2.718 21.403 1.00 21.12 ? 30 PRO A CB 1 ATOM 189 C CG . PRO A 1 30 ? 2.013 3.207 21.767 1.00 23.06 ? 30 PRO A CG 1 ATOM 190 C CD . PRO A 1 30 ? 2.345 2.498 23.108 1.00 22.91 ? 30 PRO A CD 1 ATOM 191 N N . PHE A 1 31 ? -2.029 0.821 22.539 1.00 18.81 ? 31 PHE A N 1 ATOM 192 C CA . PHE A 1 31 ? -2.607 -0.511 22.382 1.00 18.30 ? 31 PHE A CA 1 ATOM 193 C C . PHE A 1 31 ? -1.743 -1.413 21.441 1.00 18.53 ? 31 PHE A C 1 ATOM 194 O O . PHE A 1 31 ? -1.294 -0.948 20.382 1.00 16.40 ? 31 PHE A O 1 ATOM 195 C CB . PHE A 1 31 ? -4.050 -0.473 21.873 1.00 18.51 ? 31 PHE A CB 1 ATOM 196 C CG . PHE A 1 31 ? -4.530 -1.827 21.409 1.00 18.74 ? 31 PHE A CG 1 ATOM 197 C CD1 . PHE A 1 31 ? -4.883 -2.817 22.329 1.00 19.46 ? 31 PHE A CD1 1 ATOM 198 C CD2 . PHE A 1 31 ? -4.512 -2.167 20.056 1.00 20.21 ? 31 PHE A CD2 1 ATOM 199 C CE1 . PHE A 1 31 ? -5.280 -4.082 21.901 1.00 19.72 ? 31 PHE A CE1 1 ATOM 200 C CE2 . PHE A 1 31 ? -4.882 -3.463 19.636 1.00 18.03 ? 31 PHE A CE2 1 ATOM 201 C CZ . PHE A 1 31 ? -5.248 -4.403 20.561 1.00 18.86 ? 31 PHE A CZ 1 ATOM 202 N N . PHE A 1 32 ? -1.493 -2.656 21.886 1.00 18.77 ? 32 PHE A N 1 ATOM 203 C CA . PHE A 1 32 ? -0.881 -3.721 21.087 1.00 19.95 ? 32 PHE A CA 1 ATOM 204 C C . PHE A 1 32 ? -1.588 -4.997 21.369 1.00 19.95 ? 32 PHE A C 1 ATOM 205 O O . PHE A 1 32 ? -1.851 -5.329 22.524 1.00 20.97 ? 32 PHE A O 1 ATOM 206 C CB . PHE A 1 32 ? 0.630 -3.880 21.316 1.00 20.70 ? 32 PHE A CB 1 ATOM 207 C CG . PHE A 1 32 ? 1.025 -4.161 22.749 1.00 22.95 ? 32 PHE A CG 1 ATOM 208 C CD1 . PHE A 1 32 ? 1.190 -3.108 23.663 1.00 25.54 ? 32 PHE A CD1 1 ATOM 209 C CD2 . PHE A 1 32 ? 1.291 -5.467 23.167 1.00 24.96 ? 32 PHE A CD2 1 ATOM 210 C CE1 . PHE A 1 32 ? 1.562 -3.341 24.958 1.00 25.74 ? 32 PHE A CE1 1 ATOM 211 C CE2 . PHE A 1 32 ? 1.672 -5.721 24.477 1.00 26.35 ? 32 PHE A CE2 1 ATOM 212 C CZ . PHE A 1 32 ? 1.802 -4.648 25.376 1.00 26.57 ? 32 PHE A CZ 1 ATOM 213 N N . SER A 1 33 ? -1.934 -5.738 20.315 1.00 20.67 ? 33 SER A N 1 ATOM 214 C CA . SER A 1 33 ? -2.767 -6.927 20.483 1.00 19.35 ? 33 SER A CA 1 ATOM 215 C C . SER A 1 33 ? -1.961 -8.062 21.119 1.00 20.27 ? 33 SER A C 1 ATOM 216 O O . SER A 1 33 ? -0.812 -8.290 20.770 1.00 20.65 ? 33 SER A O 1 ATOM 217 C CB . SER A 1 33 ? -3.358 -7.380 19.142 1.00 19.04 ? 33 SER A CB 1 ATOM 218 O OG . SER A 1 33 ? -4.112 -8.578 19.309 1.00 17.92 ? 33 SER A OG 1 ATOM 219 N N . LEU A 1 34 ? -2.591 -8.758 22.043 1.00 20.94 ? 34 LEU A N 1 ATOM 220 C CA . LEU A 1 34 ? -2.002 -9.874 22.746 1.00 22.64 ? 34 LEU A CA 1 ATOM 221 C C . LEU A 1 34 ? -2.591 -11.187 22.240 1.00 23.56 ? 34 LEU A C 1 ATOM 222 O O . LEU A 1 34 ? -2.467 -12.215 22.894 1.00 23.05 ? 34 LEU A O 1 ATOM 223 C CB . LEU A 1 34 ? -2.338 -9.730 24.217 1.00 21.62 ? 34 LEU A CB 1 ATOM 224 C CG . LEU A 1 34 ? -1.620 -8.512 24.818 1.00 23.00 ? 34 LEU A CG 1 ATOM 225 C CD1 . LEU A 1 34 ? -2.170 -8.255 26.204 1.00 20.78 ? 34 LEU A CD1 1 ATOM 226 C CD2 . LEU A 1 34 ? -0.107 -8.768 24.774 1.00 21.94 ? 34 LEU A CD2 1 ATOM 227 N N . ALA A 1 35 ? -3.268 -11.135 21.098 1.00 26.07 ? 35 ALA A N 1 ATOM 228 C CA . ALA A 1 35 ? -3.891 -12.358 20.514 1.00 28.49 ? 35 ALA A CA 1 ATOM 229 C C . ALA A 1 35 ? -2.922 -13.536 20.403 1.00 29.77 ? 35 ALA A C 1 ATOM 230 O O . ALA A 1 35 ? -3.317 -14.637 20.720 1.00 31.04 ? 35 ALA A O 1 ATOM 231 C CB . ALA A 1 35 ? -4.540 -12.070 19.146 1.00 27.53 ? 35 ALA A CB 1 ATOM 232 N N . ASN A 1 36 ? -1.683 -13.311 19.962 1.00 31.39 ? 36 ASN A N 1 ATOM 233 C CA A ASN A 1 36 ? -0.686 -14.383 19.847 0.50 33.06 ? 36 ASN A CA 1 ATOM 234 C CA B ASN A 1 36 ? -0.689 -14.385 19.845 0.50 32.92 ? 36 ASN A CA 1 ATOM 235 C C . ASN A 1 36 ? -0.182 -14.871 21.198 1.00 33.96 ? 36 ASN A C 1 ATOM 236 O O . ASN A 1 36 ? 0.322 -15.995 21.324 1.00 34.72 ? 36 ASN A O 1 ATOM 237 C CB A ASN A 1 36 ? 0.505 -13.912 19.016 0.50 33.12 ? 36 ASN A CB 1 ATOM 238 C CB B ASN A 1 36 ? 0.501 -13.946 18.982 0.50 32.98 ? 36 ASN A CB 1 ATOM 239 C CG A ASN A 1 36 ? 0.085 -13.303 17.697 0.50 34.40 ? 36 ASN A CG 1 ATOM 240 C CG B ASN A 1 36 ? 1.563 -13.200 19.775 0.50 33.34 ? 36 ASN A CG 1 ATOM 241 O OD1 A ASN A 1 36 ? -0.558 -13.962 16.866 0.50 33.77 ? 36 ASN A OD1 1 ATOM 242 O OD1 B ASN A 1 36 ? 2.732 -13.583 19.772 0.50 33.79 ? 36 ASN A OD1 1 ATOM 243 N ND2 A ASN A 1 36 ? 0.446 -12.035 17.490 0.50 34.73 ? 36 ASN A ND2 1 ATOM 244 N ND2 B ASN A 1 36 ? 1.158 -12.134 20.465 0.50 35.27 ? 36 ASN A ND2 1 ATOM 245 N N . GLU A 1 37 ? -0.296 -14.019 22.215 1.00 35.12 ? 37 GLU A N 1 ATOM 246 C CA . GLU A 1 37 ? 0.185 -14.384 23.550 1.00 36.07 ? 37 GLU A CA 1 ATOM 247 C C . GLU A 1 37 ? -0.920 -15.154 24.281 1.00 36.26 ? 37 GLU A C 1 ATOM 248 O O . GLU A 1 37 ? -0.722 -15.676 25.382 1.00 36.07 ? 37 GLU A O 1 ATOM 249 C CB . GLU A 1 37 ? 0.640 -13.129 24.354 1.00 36.33 ? 37 GLU A CB 1 ATOM 250 C CG . GLU A 1 37 ? 1.773 -12.309 23.725 1.00 38.12 ? 37 GLU A CG 1 ATOM 251 C CD . GLU A 1 37 ? 3.166 -12.757 24.145 1.00 43.15 ? 37 GLU A CD 1 ATOM 252 O OE1 . GLU A 1 37 ? 3.337 -13.935 24.566 1.00 45.23 ? 37 GLU A OE1 1 ATOM 253 O OE2 . GLU A 1 37 ? 4.101 -11.926 24.066 1.00 45.02 ? 37 GLU A OE2 1 ATOM 254 N N . SER A 1 38 ? -2.093 -15.219 23.666 1.00 36.01 ? 38 SER A N 1 ATOM 255 C CA . SER A 1 38 ? -3.193 -16.007 24.212 1.00 35.84 ? 38 SER A CA 1 ATOM 256 C C . SER A 1 38 ? -2.986 -17.519 24.062 1.00 36.61 ? 38 SER A C 1 ATOM 257 O O . SER A 1 38 ? -2.949 -18.037 22.941 1.00 37.52 ? 38 SER A O 1 ATOM 258 C CB . SER A 1 38 ? -4.491 -15.628 23.496 1.00 35.77 ? 38 SER A CB 1 ATOM 259 O OG . SER A 1 38 ? -5.623 -15.998 24.279 1.00 32.80 ? 38 SER A OG 1 ATOM 260 N N . VAL A 1 39 ? -2.924 -18.254 25.164 1.00 36.64 ? 39 VAL A N 1 ATOM 261 C CA . VAL A 1 39 ? -2.789 -19.697 25.049 1.00 36.82 ? 39 VAL A CA 1 ATOM 262 C C . VAL A 1 39 ? -4.066 -20.293 24.508 1.00 36.56 ? 39 VAL A C 1 ATOM 263 O O . VAL A 1 39 ? -4.032 -21.294 23.798 1.00 37.58 ? 39 VAL A O 1 ATOM 264 C CB . VAL A 1 39 ? -2.422 -20.351 26.394 1.00 37.35 ? 39 VAL A CB 1 ATOM 265 C CG1 . VAL A 1 39 ? -2.359 -21.881 26.265 1.00 37.52 ? 39 VAL A CG1 1 ATOM 266 C CG2 . VAL A 1 39 ? -1.073 -19.793 26.874 1.00 39.29 ? 39 VAL A CG2 1 ATOM 267 N N . ILE A 1 40 ? -5.202 -19.702 24.866 1.00 35.97 ? 40 ILE A N 1 ATOM 268 C CA . ILE A 1 40 ? -6.513 -20.174 24.417 1.00 34.60 ? 40 ILE A CA 1 ATOM 269 C C . ILE A 1 40 ? -6.859 -19.321 23.190 1.00 35.59 ? 40 ILE A C 1 ATOM 270 O O . ILE A 1 40 ? -6.534 -18.133 23.135 1.00 35.16 ? 40 ILE A O 1 ATOM 271 C CB . ILE A 1 40 ? -7.570 -20.058 25.562 1.00 34.34 ? 40 ILE A CB 1 ATOM 272 C CG1 . ILE A 1 40 ? -7.170 -20.920 26.765 1.00 32.61 ? 40 ILE A CG1 1 ATOM 273 C CG2 . ILE A 1 40 ? -9.010 -20.442 25.107 1.00 32.76 ? 40 ILE A CG2 1 ATOM 274 C CD1 . ILE A 1 40 ? -8.015 -20.626 28.078 1.00 29.58 ? 40 ILE A CD1 1 ATOM 275 N N . SER A 1 41 ? -7.500 -19.934 22.200 1.00 35.93 ? 41 SER A N 1 ATOM 276 C CA . SER A 1 41 ? -7.746 -19.295 20.922 1.00 37.04 ? 41 SER A CA 1 ATOM 277 C C . SER A 1 41 ? -8.871 -18.311 21.072 1.00 37.17 ? 41 SER A C 1 ATOM 278 O O . SER A 1 41 ? -9.877 -18.618 21.690 1.00 37.35 ? 41 SER A O 1 ATOM 279 C CB . SER A 1 41 ? -8.108 -20.354 19.856 1.00 37.42 ? 41 SER A CB 1 ATOM 280 O OG . SER A 1 41 ? -8.467 -19.740 18.624 1.00 39.15 ? 41 SER A OG 1 ATOM 281 N N . PRO A 1 42 ? -8.716 -17.128 20.500 1.00 38.33 ? 42 PRO A N 1 ATOM 282 C CA . PRO A 1 42 ? -9.782 -16.147 20.615 1.00 40.03 ? 42 PRO A CA 1 ATOM 283 C C . PRO A 1 42 ? -10.974 -16.458 19.721 1.00 41.21 ? 42 PRO A C 1 ATOM 284 O O . PRO A 1 42 ? -12.065 -15.898 19.932 1.00 41.77 ? 42 PRO A O 1 ATOM 285 C CB . PRO A 1 42 ? -9.120 -14.813 20.203 1.00 39.49 ? 42 PRO A CB 1 ATOM 286 C CG . PRO A 1 42 ? -7.650 -15.065 20.240 1.00 40.04 ? 42 PRO A CG 1 ATOM 287 C CD . PRO A 1 42 ? -7.505 -16.555 19.906 1.00 38.90 ? 42 PRO A CD 1 ATOM 288 N N . GLU A 1 43 ? -10.768 -17.334 18.740 1.00 42.01 ? 43 GLU A N 1 ATOM 289 C CA . GLU A 1 43 ? -11.803 -17.653 17.777 1.00 42.90 ? 43 GLU A CA 1 ATOM 290 C C . GLU A 1 43 ? -13.032 -18.193 18.476 1.00 42.66 ? 43 GLU A C 1 ATOM 291 O O . GLU A 1 43 ? -12.937 -18.843 19.537 1.00 42.72 ? 43 GLU A O 1 ATOM 292 C CB . GLU A 1 43 ? -11.286 -18.663 16.756 1.00 43.30 ? 43 GLU A CB 1 ATOM 293 C CG . GLU A 1 43 ? -10.837 -18.014 15.440 1.00 48.53 ? 43 GLU A CG 1 ATOM 294 C CD . GLU A 1 43 ? -9.320 -17.718 15.365 1.00 55.58 ? 43 GLU A CD 1 ATOM 295 O OE1 . GLU A 1 43 ? -8.567 -18.436 14.633 1.00 57.51 ? 43 GLU A OE1 1 ATOM 296 O OE2 . GLU A 1 43 ? -8.877 -16.751 16.025 1.00 58.22 ? 43 GLU A OE2 1 ATOM 297 N N . VAL A 1 44 ? -14.192 -17.905 17.893 1.00 42.48 ? 44 VAL A N 1 ATOM 298 C CA . VAL A 1 44 ? -15.448 -18.505 18.362 1.00 42.13 ? 44 VAL A CA 1 ATOM 299 C C . VAL A 1 44 ? -15.307 -19.981 18.112 1.00 42.41 ? 44 VAL A C 1 ATOM 300 O O . VAL A 1 44 ? -14.920 -20.384 17.026 1.00 43.22 ? 44 VAL A O 1 ATOM 301 C CB . VAL A 1 44 ? -16.683 -17.994 17.577 1.00 41.98 ? 44 VAL A CB 1 ATOM 302 C CG1 . VAL A 1 44 ? -17.950 -18.590 18.111 1.00 40.54 ? 44 VAL A CG1 1 ATOM 303 C CG2 . VAL A 1 44 ? -16.759 -16.464 17.609 1.00 41.83 ? 44 VAL A CG2 1 ATOM 304 N N . PRO A 1 45 ? -15.580 -20.798 19.123 1.00 42.61 ? 45 PRO A N 1 ATOM 305 C CA . PRO A 1 45 ? -15.408 -22.232 18.889 1.00 42.40 ? 45 PRO A CA 1 ATOM 306 C C . PRO A 1 45 ? -16.502 -22.801 17.989 1.00 42.27 ? 45 PRO A C 1 ATOM 307 O O . PRO A 1 45 ? -17.622 -22.238 17.898 1.00 42.14 ? 45 PRO A O 1 ATOM 308 C CB . PRO A 1 45 ? -15.506 -22.846 20.298 1.00 42.33 ? 45 PRO A CB 1 ATOM 309 C CG . PRO A 1 45 ? -15.289 -21.697 21.253 1.00 42.47 ? 45 PRO A CG 1 ATOM 310 C CD . PRO A 1 45 ? -15.803 -20.477 20.545 1.00 42.38 ? 45 PRO A CD 1 ATOM 311 N N . ALA A 1 46 ? -16.177 -23.925 17.353 1.00 41.20 ? 46 ALA A N 1 ATOM 312 C CA . ALA A 1 46 ? -17.085 -24.570 16.430 1.00 40.24 ? 46 ALA A CA 1 ATOM 313 C C . ALA A 1 46 ? -18.355 -25.005 17.173 1.00 39.22 ? 46 ALA A C 1 ATOM 314 O O . ALA A 1 46 ? -18.287 -25.544 18.291 1.00 39.76 ? 46 ALA A O 1 ATOM 315 C CB . ALA A 1 46 ? -16.357 -25.786 15.756 1.00 40.85 ? 46 ALA A CB 1 ATOM 316 N N . GLY A 1 47 ? -19.515 -24.763 16.568 1.00 38.01 ? 47 GLY A N 1 ATOM 317 C CA . GLY A 1 47 ? -20.801 -25.131 17.172 1.00 35.27 ? 47 GLY A CA 1 ATOM 318 C C . GLY A 1 47 ? -21.318 -24.002 18.048 1.00 34.66 ? 47 GLY A C 1 ATOM 319 O O . GLY A 1 47 ? -22.433 -24.091 18.617 1.00 34.49 ? 47 GLY A O 1 ATOM 320 N N . CYS A 1 48 ? -20.521 -22.936 18.168 1.00 32.72 ? 48 CYS A N 1 ATOM 321 C CA . CYS A 1 48 ? -20.861 -21.833 19.063 1.00 31.52 ? 48 CYS A CA 1 ATOM 322 C C . CYS A 1 48 ? -21.218 -20.561 18.306 1.00 30.37 ? 48 CYS A C 1 ATOM 323 O O . CYS A 1 48 ? -20.575 -20.183 17.297 1.00 29.05 ? 48 CYS A O 1 ATOM 324 C CB . CYS A 1 48 ? -19.702 -21.543 20.045 1.00 31.74 ? 48 CYS A CB 1 ATOM 325 S SG . CYS A 1 48 ? -19.354 -22.957 21.187 1.00 33.32 ? 48 CYS A SG 1 ATOM 326 N N . ARG A 1 49 ? -22.217 -19.868 18.832 1.00 29.25 ? 49 ARG A N 1 ATOM 327 C CA A ARG A 1 49 ? -22.653 -18.585 18.288 0.50 28.79 ? 49 ARG A CA 1 ATOM 328 C CA B ARG A 1 49 ? -22.522 -18.550 18.290 0.50 28.51 ? 49 ARG A CA 1 ATOM 329 C C . ARG A 1 49 ? -22.652 -17.475 19.362 1.00 27.01 ? 49 ARG A C 1 ATOM 330 O O . ARG A 1 49 ? -23.305 -17.640 20.364 1.00 27.13 ? 49 ARG A O 1 ATOM 331 C CB A ARG A 1 49 ? -24.077 -18.788 17.724 0.50 28.83 ? 49 ARG A CB 1 ATOM 332 C CB B ARG A 1 49 ? -23.756 -18.590 17.361 0.50 28.62 ? 49 ARG A CB 1 ATOM 333 C CG A ARG A 1 49 ? -24.615 -17.661 16.868 0.50 30.95 ? 49 ARG A CG 1 ATOM 334 C CG B ARG A 1 49 ? -23.535 -17.769 16.087 0.50 29.35 ? 49 ARG A CG 1 ATOM 335 C CD A ARG A 1 49 ? -26.041 -17.979 16.478 0.50 33.31 ? 49 ARG A CD 1 ATOM 336 C CD B ARG A 1 49 ? -24.663 -17.860 15.081 0.50 30.92 ? 49 ARG A CD 1 ATOM 337 N NE A ARG A 1 49 ? -26.655 -18.913 17.422 0.50 35.01 ? 49 ARG A NE 1 ATOM 338 N NE B ARG A 1 49 ? -24.153 -17.609 13.744 0.50 31.65 ? 49 ARG A NE 1 ATOM 339 C CZ A ARG A 1 49 ? -27.646 -18.590 18.247 0.50 35.24 ? 49 ARG A CZ 1 ATOM 340 C CZ B ARG A 1 49 ? -23.982 -18.561 12.834 0.50 32.45 ? 49 ARG A CZ 1 ATOM 341 N NH1 A ARG A 1 49 ? -28.133 -17.359 18.249 0.50 33.91 ? 49 ARG A NH1 1 ATOM 342 N NH1 B ARG A 1 49 ? -24.316 -19.818 13.110 0.50 32.28 ? 49 ARG A NH1 1 ATOM 343 N NH2 A ARG A 1 49 ? -28.150 -19.500 19.069 0.50 36.14 ? 49 ARG A NH2 1 ATOM 344 N NH2 B ARG A 1 49 ? -23.491 -18.256 11.643 0.50 32.58 ? 49 ARG A NH2 1 ATOM 345 N N . VAL A 1 50 ? -21.970 -16.356 19.123 1.00 26.29 ? 50 VAL A N 1 ATOM 346 C CA . VAL A 1 50 ? -22.025 -15.162 20.007 1.00 23.73 ? 50 VAL A CA 1 ATOM 347 C C . VAL A 1 50 ? -23.406 -14.441 19.979 1.00 24.23 ? 50 VAL A C 1 ATOM 348 O O . VAL A 1 50 ? -23.886 -13.963 18.923 1.00 24.37 ? 50 VAL A O 1 ATOM 349 C CB . VAL A 1 50 ? -20.954 -14.107 19.665 1.00 23.70 ? 50 VAL A CB 1 ATOM 350 C CG1 . VAL A 1 50 ? -20.883 -12.983 20.763 1.00 21.08 ? 50 VAL A CG1 1 ATOM 351 C CG2 . VAL A 1 50 ? -19.597 -14.714 19.509 1.00 24.13 ? 50 VAL A CG2 1 ATOM 352 N N . THR A 1 51 ? -24.020 -14.358 21.152 1.00 22.97 ? 51 THR A N 1 ATOM 353 C CA . THR A 1 51 ? -25.282 -13.728 21.344 1.00 23.32 ? 51 THR A CA 1 ATOM 354 C C . THR A 1 51 ? -25.215 -12.412 22.167 1.00 23.03 ? 51 THR A C 1 ATOM 355 O O . THR A 1 51 ? -26.235 -11.780 22.404 1.00 22.68 ? 51 THR A O 1 ATOM 356 C CB . THR A 1 51 ? -26.239 -14.710 22.038 1.00 24.55 ? 51 THR A CB 1 ATOM 357 O OG1 . THR A 1 51 ? -25.705 -15.120 23.310 1.00 24.51 ? 51 THR A OG1 1 ATOM 358 C CG2 . THR A 1 51 ? -26.473 -16.003 21.177 1.00 24.87 ? 51 THR A CG2 1 ATOM 359 N N . PHE A 1 52 ? -24.018 -11.994 22.596 1.00 22.98 ? 52 PHE A N 1 ATOM 360 C CA . PHE A 1 52 ? -23.876 -10.764 23.439 1.00 20.41 ? 52 PHE A CA 1 ATOM 361 C C . PHE A 1 52 ? -22.451 -10.296 23.325 1.00 19.28 ? 52 PHE A C 1 ATOM 362 O O . PHE A 1 52 ? -21.523 -11.101 23.389 1.00 18.74 ? 52 PHE A O 1 ATOM 363 C CB . PHE A 1 52 ? -24.226 -11.107 24.901 1.00 20.39 ? 52 PHE A CB 1 ATOM 364 C CG . PHE A 1 52 ? -23.903 -10.012 25.928 1.00 19.52 ? 52 PHE A CG 1 ATOM 365 C CD1 . PHE A 1 52 ? -22.617 -9.859 26.451 1.00 18.01 ? 52 PHE A CD1 1 ATOM 366 C CD2 . PHE A 1 52 ? -24.930 -9.194 26.425 1.00 18.74 ? 52 PHE A CD2 1 ATOM 367 C CE1 . PHE A 1 52 ? -22.352 -8.874 27.389 1.00 17.94 ? 52 PHE A CE1 1 ATOM 368 C CE2 . PHE A 1 52 ? -24.663 -8.206 27.370 1.00 19.69 ? 52 PHE A CE2 1 ATOM 369 C CZ . PHE A 1 52 ? -23.366 -8.030 27.818 1.00 19.34 ? 52 PHE A CZ 1 ATOM 370 N N . ALA A 1 53 ? -22.258 -8.986 23.190 1.00 19.22 ? 53 ALA A N 1 ATOM 371 C CA . ALA A 1 53 ? -20.906 -8.412 23.268 1.00 18.20 ? 53 ALA A CA 1 ATOM 372 C C . ALA A 1 53 ? -20.876 -7.019 23.892 1.00 17.35 ? 53 ALA A C 1 ATOM 373 O O . ALA A 1 53 ? -21.590 -6.132 23.470 1.00 16.83 ? 53 ALA A O 1 ATOM 374 C CB . ALA A 1 53 ? -20.166 -8.447 21.883 1.00 17.67 ? 53 ALA A CB 1 ATOM 375 N N . GLN A 1 54 ? -20.044 -6.870 24.920 1.00 16.97 ? 54 GLN A N 1 ATOM 376 C CA . GLN A 1 54 ? -19.810 -5.590 25.608 1.00 16.75 ? 54 GLN A CA 1 ATOM 377 C C . GLN A 1 54 ? -18.363 -5.261 25.419 1.00 16.15 ? 54 GLN A C 1 ATOM 378 O O . GLN A 1 54 ? -17.519 -6.119 25.571 1.00 16.91 ? 54 GLN A O 1 ATOM 379 C CB . GLN A 1 54 ? -20.096 -5.698 27.116 1.00 17.46 ? 54 GLN A CB 1 ATOM 380 C CG . GLN A 1 54 ? -19.890 -4.408 27.913 1.00 18.48 ? 54 GLN A CG 1 ATOM 381 C CD . GLN A 1 54 ? -20.814 -4.329 29.085 1.00 22.24 ? 54 GLN A CD 1 ATOM 382 O OE1 . GLN A 1 54 ? -22.015 -4.543 28.980 1.00 23.38 ? 54 GLN A OE1 1 ATOM 383 N NE2 . GLN A 1 54 ? -20.252 -4.044 30.236 1.00 24.60 ? 54 GLN A NE2 1 ATOM 384 N N . VAL A 1 55 ? -18.066 -4.029 25.031 1.00 15.56 ? 55 VAL A N 1 ATOM 385 C CA . VAL A 1 55 ? -16.689 -3.586 25.036 1.00 15.44 ? 55 VAL A CA 1 ATOM 386 C C . VAL A 1 55 ? -16.584 -2.419 26.045 1.00 15.64 ? 55 VAL A C 1 ATOM 387 O O . VAL A 1 55 ? -17.486 -1.576 26.166 1.00 16.95 ? 55 VAL A O 1 ATOM 388 C CB . VAL A 1 55 ? -16.177 -3.249 23.652 1.00 15.76 ? 55 VAL A CB 1 ATOM 389 C CG1 . VAL A 1 55 ? -17.061 -2.234 22.997 1.00 17.41 ? 55 VAL A CG1 1 ATOM 390 C CG2 . VAL A 1 55 ? -14.717 -2.714 23.687 1.00 16.56 ? 55 VAL A CG2 1 ATOM 391 N N . LEU A 1 56 ? -15.543 -2.483 26.850 1.00 14.80 ? 56 LEU A N 1 ATOM 392 C CA . LEU A 1 56 ? -15.168 -1.421 27.771 1.00 13.70 ? 56 LEU A CA 1 ATOM 393 C C . LEU A 1 56 ? -13.823 -0.955 27.231 1.00 13.14 ? 56 LEU A C 1 ATOM 394 O O . LEU A 1 56 ? -12.877 -1.725 27.206 1.00 14.08 ? 56 LEU A O 1 ATOM 395 C CB . LEU A 1 56 ? -15.033 -1.979 29.231 1.00 12.23 ? 56 LEU A CB 1 ATOM 396 C CG . LEU A 1 56 ? -14.435 -0.970 30.256 1.00 14.23 ? 56 LEU A CG 1 ATOM 397 C CD1 . LEU A 1 56 ? -15.259 0.316 30.403 1.00 9.54 ? 56 LEU A CD1 1 ATOM 398 C CD2 . LEU A 1 56 ? -14.338 -1.614 31.602 1.00 11.76 ? 56 LEU A CD2 1 ATOM 399 N N . SER A 1 57 ? -13.729 0.294 26.798 1.00 14.21 ? 57 SER A N 1 ATOM 400 C CA . SER A 1 57 ? -12.519 0.772 26.155 1.00 14.61 ? 57 SER A CA 1 ATOM 401 C C . SER A 1 57 ? -11.963 1.978 26.944 1.00 15.45 ? 57 SER A C 1 ATOM 402 O O . SER A 1 57 ? -12.742 2.783 27.445 1.00 14.61 ? 57 SER A O 1 ATOM 403 C CB . SER A 1 57 ? -12.899 1.250 24.766 1.00 15.50 ? 57 SER A CB 1 ATOM 404 O OG . SER A 1 57 ? -11.771 1.769 24.026 1.00 15.31 ? 57 SER A OG 1 ATOM 405 N N . ARG A 1 58 ? -10.631 2.123 26.973 1.00 14.84 ? 58 ARG A N 1 ATOM 406 C CA . ARG A 1 58 ? -10.020 3.323 27.464 1.00 15.72 ? 58 ARG A CA 1 ATOM 407 C C . ARG A 1 58 ? -9.968 4.362 26.334 1.00 15.95 ? 58 ARG A C 1 ATOM 408 O O . ARG A 1 58 ? -10.112 3.971 25.188 1.00 16.00 ? 58 ARG A O 1 ATOM 409 C CB . ARG A 1 58 ? -8.601 3.068 27.922 1.00 15.36 ? 58 ARG A CB 1 ATOM 410 C CG . ARG A 1 58 ? -7.968 4.272 28.659 1.00 14.16 ? 58 ARG A CG 1 ATOM 411 C CD . ARG A 1 58 ? -6.546 3.913 29.056 1.00 11.53 ? 58 ARG A CD 1 ATOM 412 N NE . ARG A 1 58 ? -5.818 5.067 29.548 1.00 15.80 ? 58 ARG A NE 1 ATOM 413 C CZ . ARG A 1 58 ? -4.489 5.126 29.733 1.00 12.84 ? 58 ARG A CZ 1 ATOM 414 N NH1 . ARG A 1 58 ? -3.683 4.090 29.519 1.00 9.32 ? 58 ARG A NH1 1 ATOM 415 N NH2 . ARG A 1 58 ? -3.974 6.270 30.104 1.00 15.05 ? 58 ARG A NH2 1 ATOM 416 N N . HIS A 1 59 ? -9.738 5.642 26.668 1.00 14.34 ? 59 HIS A N 1 ATOM 417 C CA . HIS A 1 59 ? -9.617 6.674 25.663 1.00 15.29 ? 59 HIS A CA 1 ATOM 418 C C . HIS A 1 59 ? -8.301 6.408 24.970 1.00 14.78 ? 59 HIS A C 1 ATOM 419 O O . HIS A 1 59 ? -7.580 5.511 25.389 1.00 14.61 ? 59 HIS A O 1 ATOM 420 C CB . HIS A 1 59 ? -9.608 8.051 26.322 1.00 15.04 ? 59 HIS A CB 1 ATOM 421 C CG . HIS A 1 59 ? -8.487 8.205 27.282 1.00 16.69 ? 59 HIS A CG 1 ATOM 422 N ND1 . HIS A 1 59 ? -7.151 8.266 26.881 1.00 15.33 ? 59 HIS A ND1 1 ATOM 423 C CD2 . HIS A 1 59 ? -8.496 8.264 28.637 1.00 12.13 ? 59 HIS A CD2 1 ATOM 424 C CE1 . HIS A 1 59 ? -6.399 8.330 27.971 1.00 15.36 ? 59 HIS A CE1 1 ATOM 425 N NE2 . HIS A 1 59 ? -7.198 8.365 29.038 1.00 14.19 ? 59 HIS A NE2 1 ATOM 426 N N . GLY A 1 60 ? -8.005 7.125 23.893 1.00 14.22 ? 60 GLY A N 1 ATOM 427 C CA . GLY A 1 60 ? -6.813 6.796 23.083 1.00 13.95 ? 60 GLY A CA 1 ATOM 428 C C . GLY A 1 60 ? -5.591 7.500 23.596 1.00 15.04 ? 60 GLY A C 1 ATOM 429 O O . GLY A 1 60 ? -5.641 8.203 24.610 1.00 15.77 ? 60 GLY A O 1 ATOM 430 N N . ALA A 1 61 ? -4.475 7.311 22.908 1.00 16.51 ? 61 ALA A N 1 ATOM 431 C CA . ALA A 1 61 ? -3.278 8.020 23.241 1.00 17.85 ? 61 ALA A CA 1 ATOM 432 C C . ALA A 1 61 ? -3.553 9.541 23.366 1.00 19.88 ? 61 ALA A C 1 ATOM 433 O O . ALA A 1 61 ? -4.318 10.146 22.583 1.00 20.63 ? 61 ALA A O 1 ATOM 434 C CB . ALA A 1 61 ? -2.234 7.730 22.231 1.00 16.08 ? 61 ALA A CB 1 ATOM 435 N N . ARG A 1 62 ? -2.919 10.166 24.349 1.00 20.74 ? 62 ARG A N 1 ATOM 436 C CA . ARG A 1 62 ? -3.173 11.561 24.638 1.00 20.66 ? 62 ARG A CA 1 ATOM 437 C C . ARG A 1 62 ? -1.890 12.358 24.858 1.00 20.44 ? 62 ARG A C 1 ATOM 438 O O . ARG A 1 62 ? -0.790 11.818 24.975 1.00 20.48 ? 62 ARG A O 1 ATOM 439 C CB . ARG A 1 62 ? -4.084 11.681 25.888 1.00 21.65 ? 62 ARG A CB 1 ATOM 440 C CG . ARG A 1 62 ? -3.463 11.109 27.195 1.00 21.84 ? 62 ARG A CG 1 ATOM 441 C CD . ARG A 1 62 ? -4.289 11.580 28.418 1.00 22.61 ? 62 ARG A CD 1 ATOM 442 N NE . ARG A 1 62 ? -3.804 10.943 29.632 1.00 25.07 ? 62 ARG A NE 1 ATOM 443 C CZ . ARG A 1 62 ? -2.730 11.307 30.346 1.00 24.24 ? 62 ARG A CZ 1 ATOM 444 N NH1 . ARG A 1 62 ? -1.981 12.339 30.003 1.00 22.03 ? 62 ARG A NH1 1 ATOM 445 N NH2 . ARG A 1 62 ? -2.392 10.598 31.423 1.00 23.13 ? 62 ARG A NH2 1 ATOM 446 N N . TYR A 1 63 ? -2.040 13.669 24.889 1.00 20.68 ? 63 TYR A N 1 ATOM 447 C CA . TYR A 1 63 ? -0.985 14.544 25.388 1.00 22.17 ? 63 TYR A CA 1 ATOM 448 C C . TYR A 1 63 ? -0.905 14.424 26.919 1.00 22.74 ? 63 TYR A C 1 ATOM 449 O O . TYR A 1 63 ? -1.885 13.992 27.575 1.00 21.41 ? 63 TYR A O 1 ATOM 450 C CB . TYR A 1 63 ? -1.293 15.983 25.020 1.00 22.40 ? 63 TYR A CB 1 ATOM 451 C CG . TYR A 1 63 ? -1.227 16.253 23.541 1.00 25.29 ? 63 TYR A CG 1 ATOM 452 C CD1 . TYR A 1 63 ? -0.033 16.030 22.806 1.00 26.03 ? 63 TYR A CD1 1 ATOM 453 C CD2 . TYR A 1 63 ? -2.369 16.715 22.850 1.00 27.62 ? 63 TYR A CD2 1 ATOM 454 C CE1 . TYR A 1 63 ? 0.007 16.276 21.422 1.00 28.10 ? 63 TYR A CE1 1 ATOM 455 C CE2 . TYR A 1 63 ? -2.330 16.982 21.484 1.00 29.00 ? 63 TYR A CE2 1 ATOM 456 C CZ . TYR A 1 63 ? -1.161 16.761 20.786 1.00 30.00 ? 63 TYR A CZ 1 ATOM 457 O OH . TYR A 1 63 ? -1.191 17.024 19.455 1.00 33.81 ? 63 TYR A OH 1 ATOM 458 N N . PRO A 1 64 ? 0.238 14.811 27.505 1.00 23.91 ? 64 PRO A N 1 ATOM 459 C CA . PRO A 1 64 ? 0.340 14.846 29.007 1.00 23.71 ? 64 PRO A CA 1 ATOM 460 C C . PRO A 1 64 ? -0.719 15.747 29.642 1.00 24.19 ? 64 PRO A C 1 ATOM 461 O O . PRO A 1 64 ? -1.168 16.717 29.004 1.00 23.40 ? 64 PRO A O 1 ATOM 462 C CB . PRO A 1 64 ? 1.723 15.443 29.253 1.00 23.72 ? 64 PRO A CB 1 ATOM 463 C CG . PRO A 1 64 ? 2.532 15.159 27.934 1.00 24.37 ? 64 PRO A CG 1 ATOM 464 C CD . PRO A 1 64 ? 1.488 15.224 26.832 1.00 24.05 ? 64 PRO A CD 1 ATOM 465 N N . THR A 1 65 ? -1.140 15.452 30.865 1.00 25.30 ? 65 THR A N 1 ATOM 466 C CA . THR A 1 65 ? -2.084 16.344 31.514 1.00 27.51 ? 65 THR A CA 1 ATOM 467 C C . THR A 1 65 ? -1.362 17.693 31.639 1.00 28.82 ? 65 THR A C 1 ATOM 468 O O . THR A 1 65 ? -0.148 17.748 31.475 1.00 28.59 ? 65 THR A O 1 ATOM 469 C CB . THR A 1 65 ? -2.518 15.847 32.886 1.00 27.92 ? 65 THR A CB 1 ATOM 470 O OG1 . THR A 1 65 ? -1.359 15.789 33.711 1.00 31.12 ? 65 THR A OG1 1 ATOM 471 C CG2 . THR A 1 65 ? -3.205 14.424 32.834 1.00 26.39 ? 65 THR A CG2 1 ATOM 472 N N . ASP A 1 66 ? -2.110 18.778 31.849 1.00 30.74 ? 66 ASP A N 1 ATOM 473 C CA . ASP A 1 66 ? -1.532 20.136 31.921 1.00 33.76 ? 66 ASP A CA 1 ATOM 474 C C . ASP A 1 66 ? -0.462 20.261 33.033 1.00 33.84 ? 66 ASP A C 1 ATOM 475 O O . ASP A 1 66 ? 0.684 20.630 32.780 1.00 34.35 ? 66 ASP A O 1 ATOM 476 C CB . ASP A 1 66 ? -2.618 21.219 32.042 1.00 34.40 ? 66 ASP A CB 1 ATOM 477 C CG . ASP A 1 66 ? -2.065 22.633 31.719 1.00 39.56 ? 66 ASP A CG 1 ATOM 478 O OD1 . ASP A 1 66 ? -1.264 22.761 30.737 1.00 40.79 ? 66 ASP A OD1 1 ATOM 479 O OD2 . ASP A 1 66 ? -2.417 23.600 32.458 1.00 42.91 ? 66 ASP A OD2 1 ATOM 480 N N . SER A 1 67 ? -0.833 19.849 34.237 1.00 34.80 ? 67 SER A N 1 ATOM 481 C CA . SER A 1 67 ? 0.105 19.579 35.320 1.00 35.06 ? 67 SER A CA 1 ATOM 482 C C . SER A 1 67 ? 1.432 18.912 34.921 1.00 34.95 ? 67 SER A C 1 ATOM 483 O O . SER A 1 67 ? 2.496 19.489 35.126 1.00 34.80 ? 67 SER A O 1 ATOM 484 C CB . SER A 1 67 ? -0.588 18.677 36.305 1.00 36.15 ? 67 SER A CB 1 ATOM 485 O OG . SER A 1 67 ? -0.582 19.312 37.543 1.00 39.15 ? 67 SER A OG 1 ATOM 486 N N . LYS A 1 68 ? 1.371 17.690 34.369 1.00 34.28 ? 68 LYS A N 1 ATOM 487 C CA . LYS A 1 68 ? 2.592 16.962 34.058 1.00 33.44 ? 68 LYS A CA 1 ATOM 488 C C . LYS A 1 68 ? 3.329 17.631 32.942 1.00 32.98 ? 68 LYS A C 1 ATOM 489 O O . LYS A 1 68 ? 4.564 17.695 32.946 1.00 32.08 ? 68 LYS A O 1 ATOM 490 C CB . LYS A 1 68 ? 2.342 15.509 33.711 1.00 33.53 ? 68 LYS A CB 1 ATOM 491 C CG . LYS A 1 68 ? 1.925 14.665 34.884 1.00 34.28 ? 68 LYS A CG 1 ATOM 492 C CD . LYS A 1 68 ? 3.110 14.150 35.666 1.00 35.89 ? 68 LYS A CD 1 ATOM 493 C CE . LYS A 1 68 ? 2.669 13.187 36.737 1.00 36.46 ? 68 LYS A CE 1 ATOM 494 N NZ . LYS A 1 68 ? 3.451 11.950 36.499 1.00 40.54 ? 68 LYS A NZ 1 ATOM 495 N N . GLY A 1 69 ? 2.564 18.155 31.998 1.00 33.18 ? 69 GLY A N 1 ATOM 496 C CA . GLY A 1 69 ? 3.144 18.888 30.897 1.00 33.84 ? 69 GLY A CA 1 ATOM 497 C C . GLY A 1 69 ? 3.957 20.124 31.282 1.00 34.27 ? 69 GLY A C 1 ATOM 498 O O . GLY A 1 69 ? 4.995 20.361 30.677 1.00 33.41 ? 69 GLY A O 1 ATOM 499 N N . LYS A 1 70 ? 3.485 20.905 32.268 1.00 35.47 ? 70 LYS A N 1 ATOM 500 C CA . LYS A 1 70 ? 4.261 22.036 32.842 1.00 36.96 ? 70 LYS A CA 1 ATOM 501 C C . LYS A 1 70 ? 5.565 21.560 33.526 1.00 36.62 ? 70 LYS A C 1 ATOM 502 O O . LYS A 1 70 ? 6.610 22.206 33.423 1.00 37.55 ? 70 LYS A O 1 ATOM 503 C CB . LYS A 1 70 ? 3.456 22.780 33.897 1.00 37.72 ? 70 LYS A CB 1 ATOM 504 C CG . LYS A 1 70 ? 2.082 23.240 33.470 1.00 42.98 ? 70 LYS A CG 1 ATOM 505 C CD . LYS A 1 70 ? 2.040 24.671 32.927 1.00 49.39 ? 70 LYS A CD 1 ATOM 506 C CE . LYS A 1 70 ? 0.661 25.281 33.244 1.00 51.08 ? 70 LYS A CE 1 ATOM 507 N NZ . LYS A 1 70 ? 0.740 26.763 33.439 1.00 54.24 ? 70 LYS A NZ 1 ATOM 508 N N . LYS A 1 71 ? 5.504 20.418 34.209 1.00 35.36 ? 71 LYS A N 1 ATOM 509 C CA . LYS A 1 71 ? 6.655 19.880 34.868 1.00 34.12 ? 71 LYS A CA 1 ATOM 510 C C . LYS A 1 71 ? 7.652 19.323 33.860 1.00 34.31 ? 71 LYS A C 1 ATOM 511 O O . LYS A 1 71 ? 8.849 19.577 33.991 1.00 34.33 ? 71 LYS A O 1 ATOM 512 C CB . LYS A 1 71 ? 6.239 18.846 35.909 1.00 33.94 ? 71 LYS A CB 1 ATOM 513 C CG . LYS A 1 71 ? 5.348 19.436 36.982 1.00 35.23 ? 71 LYS A CG 1 ATOM 514 C CD . LYS A 1 71 ? 4.969 18.454 38.080 1.00 40.06 ? 71 LYS A CD 1 ATOM 515 C CE . LYS A 1 71 ? 3.968 19.143 39.015 1.00 44.53 ? 71 LYS A CE 1 ATOM 516 N NZ . LYS A 1 71 ? 3.430 18.226 40.047 1.00 45.59 ? 71 LYS A NZ 1 ATOM 517 N N . TYR A 1 72 ? 7.186 18.581 32.850 1.00 33.53 ? 72 TYR A N 1 ATOM 518 C CA . TYR A 1 72 ? 8.089 18.103 31.805 1.00 32.88 ? 72 TYR A CA 1 ATOM 519 C C . TYR A 1 72 ? 8.822 19.304 31.171 1.00 32.28 ? 72 TYR A C 1 ATOM 520 O O . TYR A 1 72 ? 10.016 19.303 30.957 1.00 30.95 ? 72 TYR A O 1 ATOM 521 C CB . TYR A 1 72 ? 7.314 17.324 30.717 1.00 32.07 ? 72 TYR A CB 1 ATOM 522 C CG . TYR A 1 72 ? 6.655 16.044 31.176 1.00 32.52 ? 72 TYR A CG 1 ATOM 523 C CD1 . TYR A 1 72 ? 6.981 15.464 32.380 1.00 31.44 ? 72 TYR A CD1 1 ATOM 524 C CD2 . TYR A 1 72 ? 5.719 15.398 30.381 1.00 31.40 ? 72 TYR A CD2 1 ATOM 525 C CE1 . TYR A 1 72 ? 6.410 14.294 32.790 1.00 31.30 ? 72 TYR A CE1 1 ATOM 526 C CE2 . TYR A 1 72 ? 5.132 14.231 30.781 1.00 28.41 ? 72 TYR A CE2 1 ATOM 527 C CZ . TYR A 1 72 ? 5.488 13.664 31.980 1.00 30.03 ? 72 TYR A CZ 1 ATOM 528 O OH . TYR A 1 72 ? 4.913 12.478 32.406 1.00 25.35 ? 72 TYR A OH 1 ATOM 529 N N . SER A 1 73 ? 8.057 20.336 30.874 1.00 33.01 ? 73 SER A N 1 ATOM 530 C CA . SER A 1 73 ? 8.528 21.435 30.055 1.00 33.44 ? 73 SER A CA 1 ATOM 531 C C . SER A 1 73 ? 9.534 22.282 30.868 1.00 33.20 ? 73 SER A C 1 ATOM 532 O O . SER A 1 73 ? 10.603 22.672 30.353 1.00 33.47 ? 73 SER A O 1 ATOM 533 C CB . SER A 1 73 ? 7.309 22.249 29.641 1.00 33.53 ? 73 SER A CB 1 ATOM 534 O OG . SER A 1 73 ? 7.712 23.447 29.046 1.00 35.58 ? 73 SER A OG 1 ATOM 535 N N . ALA A 1 74 ? 9.201 22.534 32.134 1.00 32.89 ? 74 ALA A N 1 ATOM 536 C CA . ALA A 1 74 ? 10.127 23.221 33.053 1.00 33.02 ? 74 ALA A CA 1 ATOM 537 C C . ALA A 1 74 ? 11.393 22.403 33.305 1.00 32.69 ? 74 ALA A C 1 ATOM 538 O O . ALA A 1 74 ? 12.467 22.977 33.334 1.00 32.61 ? 74 ALA A O 1 ATOM 539 C CB . ALA A 1 74 ? 9.439 23.620 34.396 1.00 33.05 ? 74 ALA A CB 1 ATOM 540 N N . LEU A 1 75 ? 11.271 21.080 33.438 1.00 32.19 ? 75 LEU A N 1 ATOM 541 C CA . LEU A 1 75 ? 12.445 20.235 33.637 1.00 33.08 ? 75 LEU A CA 1 ATOM 542 C C . LEU A 1 75 ? 13.452 20.374 32.491 1.00 33.90 ? 75 LEU A C 1 ATOM 543 O O . LEU A 1 75 ? 14.662 20.536 32.716 1.00 34.28 ? 75 LEU A O 1 ATOM 544 C CB . LEU A 1 75 ? 12.083 18.776 33.891 1.00 31.77 ? 75 LEU A CB 1 ATOM 545 C CG . LEU A 1 75 ? 13.228 17.734 33.908 1.00 34.01 ? 75 LEU A CG 1 ATOM 546 C CD1 . LEU A 1 75 ? 14.399 18.141 34.867 1.00 33.42 ? 75 LEU A CD1 1 ATOM 547 C CD2 . LEU A 1 75 ? 12.757 16.303 34.238 1.00 29.92 ? 75 LEU A CD2 1 ATOM 548 N N . ILE A 1 76 ? 12.939 20.347 31.266 1.00 35.23 ? 76 ILE A N 1 ATOM 549 C CA . ILE A 1 76 ? 13.788 20.394 30.072 1.00 35.79 ? 76 ILE A CA 1 ATOM 550 C C . ILE A 1 76 ? 14.480 21.762 29.915 1.00 36.82 ? 76 ILE A C 1 ATOM 551 O O . ILE A 1 76 ? 15.636 21.821 29.531 1.00 36.63 ? 76 ILE A O 1 ATOM 552 C CB . ILE A 1 76 ? 13.005 19.917 28.819 1.00 35.80 ? 76 ILE A CB 1 ATOM 553 C CG1 . ILE A 1 76 ? 12.642 18.437 28.995 1.00 34.01 ? 76 ILE A CG1 1 ATOM 554 C CG2 . ILE A 1 76 ? 13.829 20.125 27.545 1.00 33.23 ? 76 ILE A CG2 1 ATOM 555 C CD1 . ILE A 1 76 ? 11.353 17.996 28.315 1.00 35.04 ? 76 ILE A CD1 1 ATOM 556 N N . GLU A 1 77 ? 13.792 22.847 30.261 1.00 38.18 ? 77 GLU A N 1 ATOM 557 C CA . GLU A 1 77 ? 14.425 24.159 30.247 1.00 40.44 ? 77 GLU A CA 1 ATOM 558 C C . GLU A 1 77 ? 15.617 24.158 31.184 1.00 40.47 ? 77 GLU A C 1 ATOM 559 O O . GLU A 1 77 ? 16.740 24.500 30.773 1.00 40.70 ? 77 GLU A O 1 ATOM 560 C CB . GLU A 1 77 ? 13.484 25.240 30.704 1.00 41.40 ? 77 GLU A CB 1 ATOM 561 C CG . GLU A 1 77 ? 12.217 25.320 29.910 1.00 47.33 ? 77 GLU A CG 1 ATOM 562 C CD . GLU A 1 77 ? 11.874 26.739 29.529 1.00 53.98 ? 77 GLU A CD 1 ATOM 563 O OE1 . GLU A 1 77 ? 12.194 27.679 30.310 1.00 56.89 ? 77 GLU A OE1 1 ATOM 564 O OE2 . GLU A 1 77 ? 11.304 26.901 28.428 1.00 57.25 ? 77 GLU A OE2 1 ATOM 565 N N . GLU A 1 78 ? 15.374 23.735 32.434 1.00 40.37 ? 78 GLU A N 1 ATOM 566 C CA . GLU A 1 78 ? 16.426 23.615 33.452 1.00 39.87 ? 78 GLU A CA 1 ATOM 567 C C . GLU A 1 78 ? 17.610 22.797 32.952 1.00 39.48 ? 78 GLU A C 1 ATOM 568 O O . GLU A 1 78 ? 18.761 23.221 33.091 1.00 39.13 ? 78 GLU A O 1 ATOM 569 C CB . GLU A 1 78 ? 15.872 23.055 34.762 1.00 40.48 ? 78 GLU A CB 1 ATOM 570 C CG . GLU A 1 78 ? 15.083 24.072 35.590 1.00 42.11 ? 78 GLU A CG 1 ATOM 571 C CD . GLU A 1 78 ? 14.666 23.562 36.984 1.00 46.65 ? 78 GLU A CD 1 ATOM 572 O OE1 . GLU A 1 78 ? 13.755 24.183 37.584 1.00 48.75 ? 78 GLU A OE1 1 ATOM 573 O OE2 . GLU A 1 78 ? 15.233 22.559 37.493 1.00 48.23 ? 78 GLU A OE2 1 ATOM 574 N N . ILE A 1 79 ? 17.339 21.657 32.317 1.00 38.88 ? 79 ILE A N 1 ATOM 575 C CA . ILE A 1 79 ? 18.425 20.884 31.705 1.00 38.57 ? 79 ILE A CA 1 ATOM 576 C C . ILE A 1 79 ? 19.173 21.692 30.631 1.00 39.84 ? 79 ILE A C 1 ATOM 577 O O . ILE A 1 79 ? 20.411 21.585 30.511 1.00 39.00 ? 79 ILE A O 1 ATOM 578 C CB . ILE A 1 79 ? 17.944 19.541 31.163 1.00 38.43 ? 79 ILE A CB 1 ATOM 579 C CG1 . ILE A 1 79 ? 17.513 18.656 32.326 1.00 36.39 ? 79 ILE A CG1 1 ATOM 580 C CG2 . ILE A 1 79 ? 19.040 18.874 30.324 1.00 37.11 ? 79 ILE A CG2 1 ATOM 581 C CD1 . ILE A 1 79 ? 16.762 17.480 31.909 1.00 36.80 ? 79 ILE A CD1 1 ATOM 582 N N . GLN A 1 80 ? 18.425 22.515 29.891 1.00 40.97 ? 80 GLN A N 1 ATOM 583 C CA . GLN A 1 80 ? 19.013 23.387 28.868 1.00 42.72 ? 80 GLN A CA 1 ATOM 584 C C . GLN A 1 80 ? 19.816 24.551 29.435 1.00 42.99 ? 80 GLN A C 1 ATOM 585 O O . GLN A 1 80 ? 20.869 24.858 28.907 1.00 43.11 ? 80 GLN A O 1 ATOM 586 C CB . GLN A 1 80 ? 17.948 23.882 27.881 1.00 42.64 ? 80 GLN A CB 1 ATOM 587 C CG . GLN A 1 80 ? 17.489 22.766 26.949 1.00 43.99 ? 80 GLN A CG 1 ATOM 588 C CD . GLN A 1 80 ? 16.218 23.081 26.129 1.00 44.91 ? 80 GLN A CD 1 ATOM 589 O OE1 . GLN A 1 80 ? 15.547 24.113 26.313 1.00 43.52 ? 80 GLN A OE1 1 ATOM 590 N NE2 . GLN A 1 80 ? 15.886 22.158 25.220 1.00 42.64 ? 80 GLN A NE2 1 ATOM 591 N N . GLN A 1 81 ? 19.334 25.184 30.501 1.00 44.27 ? 81 GLN A N 1 ATOM 592 C CA . GLN A 1 81 ? 20.055 26.295 31.126 1.00 45.99 ? 81 GLN A CA 1 ATOM 593 C C . GLN A 1 81 ? 21.369 25.893 31.809 1.00 46.31 ? 81 GLN A C 1 ATOM 594 O O . GLN A 1 81 ? 22.325 26.681 31.820 1.00 46.56 ? 81 GLN A O 1 ATOM 595 C CB . GLN A 1 81 ? 19.166 26.992 32.146 1.00 46.95 ? 81 GLN A CB 1 ATOM 596 C CG . GLN A 1 81 ? 18.157 27.931 31.551 1.00 51.19 ? 81 GLN A CG 1 ATOM 597 C CD . GLN A 1 81 ? 16.860 27.927 32.348 1.00 58.98 ? 81 GLN A CD 1 ATOM 598 O OE1 . GLN A 1 81 ? 16.862 27.611 33.549 1.00 59.88 ? 81 GLN A OE1 1 ATOM 599 N NE2 . GLN A 1 81 ? 15.727 28.270 31.680 1.00 60.53 ? 81 GLN A NE2 1 ATOM 600 N N . ASN A 1 82 ? 21.421 24.663 32.340 1.00 46.24 ? 82 ASN A N 1 ATOM 601 C CA . ASN A 1 82 ? 22.471 24.238 33.271 1.00 45.67 ? 82 ASN A CA 1 ATOM 602 C C . ASN A 1 82 ? 23.565 23.412 32.609 1.00 46.51 ? 82 ASN A C 1 ATOM 603 O O . ASN A 1 82 ? 24.738 23.595 32.922 1.00 46.61 ? 82 ASN A O 1 ATOM 604 C CB . ASN A 1 82 ? 21.894 23.402 34.429 1.00 44.93 ? 82 ASN A CB 1 ATOM 605 C CG . ASN A 1 82 ? 20.981 24.190 35.387 1.00 41.48 ? 82 ASN A CG 1 ATOM 606 O OD1 . ASN A 1 82 ? 20.662 25.360 35.183 1.00 36.06 ? 82 ASN A OD1 1 ATOM 607 N ND2 . ASN A 1 82 ? 20.560 23.507 36.454 1.00 39.66 ? 82 ASN A ND2 1 ATOM 608 N N . ALA A 1 83 ? 23.189 22.493 31.722 1.00 47.35 ? 83 ALA A N 1 ATOM 609 C CA . ALA A 1 83 ? 24.154 21.527 31.184 1.00 48.30 ? 83 ALA A CA 1 ATOM 610 C C . ALA A 1 83 ? 25.167 22.155 30.233 1.00 49.31 ? 83 ALA A C 1 ATOM 611 O O . ALA A 1 83 ? 24.894 23.180 29.591 1.00 48.73 ? 83 ALA A O 1 ATOM 612 C CB . ALA A 1 83 ? 23.464 20.370 30.526 1.00 48.05 ? 83 ALA A CB 1 ATOM 613 N N . THR A 1 84 ? 26.349 21.549 30.178 1.00 50.43 ? 84 THR A N 1 ATOM 614 C CA . THR A 1 84 ? 27.428 22.075 29.354 1.00 52.16 ? 84 THR A CA 1 ATOM 615 C C . THR A 1 84 ? 27.725 21.067 28.252 1.00 53.06 ? 84 THR A C 1 ATOM 616 O O . THR A 1 84 ? 27.916 21.451 27.103 1.00 54.11 ? 84 THR A O 1 ATOM 617 C CB . THR A 1 84 ? 28.715 22.371 30.177 1.00 52.29 ? 84 THR A CB 1 ATOM 618 O OG1 . THR A 1 84 ? 29.211 21.140 30.730 1.00 52.21 ? 84 THR A OG1 1 ATOM 619 C CG2 . THR A 1 84 ? 28.428 23.387 31.323 1.00 51.77 ? 84 THR A CG2 1 ATOM 620 N N . THR A 1 85 ? 27.749 19.784 28.590 1.00 53.60 ? 85 THR A N 1 ATOM 621 C CA . THR A 1 85 ? 27.980 18.768 27.584 1.00 54.57 ? 85 THR A CA 1 ATOM 622 C C . THR A 1 85 ? 26.677 18.110 27.123 1.00 54.69 ? 85 THR A C 1 ATOM 623 O O . THR A 1 85 ? 26.076 17.323 27.855 1.00 55.29 ? 85 THR A O 1 ATOM 624 C CB . THR A 1 85 ? 29.006 17.681 28.046 1.00 55.02 ? 85 THR A CB 1 ATOM 625 O OG1 . THR A 1 85 ? 28.864 17.410 29.453 1.00 55.11 ? 85 THR A OG1 1 ATOM 626 C CG2 . THR A 1 85 ? 30.440 18.129 27.745 1.00 55.53 ? 85 THR A CG2 1 ATOM 627 N N . PHE A 1 86 ? 26.238 18.429 25.909 1.00 54.37 ? 86 PHE A N 1 ATOM 628 C CA . PHE A 1 86 ? 25.185 17.652 25.270 1.00 53.95 ? 86 PHE A CA 1 ATOM 629 C C . PHE A 1 86 ? 25.784 16.880 24.121 1.00 53.61 ? 86 PHE A C 1 ATOM 630 O O . PHE A 1 86 ? 25.824 17.394 23.005 1.00 53.99 ? 86 PHE A O 1 ATOM 631 C CB . PHE A 1 86 ? 24.122 18.560 24.679 1.00 54.02 ? 86 PHE A CB 1 ATOM 632 C CG . PHE A 1 86 ? 23.425 19.433 25.667 1.00 54.02 ? 86 PHE A CG 1 ATOM 633 C CD1 . PHE A 1 86 ? 22.287 18.974 26.333 1.00 54.40 ? 86 PHE A CD1 1 ATOM 634 C CD2 . PHE A 1 86 ? 23.855 20.741 25.884 1.00 53.93 ? 86 PHE A CD2 1 ATOM 635 C CE1 . PHE A 1 86 ? 21.610 19.802 27.235 1.00 53.79 ? 86 PHE A CE1 1 ATOM 636 C CE2 . PHE A 1 86 ? 23.166 21.592 26.771 1.00 54.07 ? 86 PHE A CE2 1 ATOM 637 C CZ . PHE A 1 86 ? 22.048 21.123 27.445 1.00 53.01 ? 86 PHE A CZ 1 ATOM 638 N N . ASP A 1 87 ? 26.286 15.678 24.363 1.00 53.02 ? 87 ASP A N 1 ATOM 639 C CA . ASP A 1 87 ? 26.849 14.931 23.243 1.00 53.23 ? 87 ASP A CA 1 ATOM 640 C C . ASP A 1 87 ? 26.466 13.467 23.207 1.00 52.34 ? 87 ASP A C 1 ATOM 641 O O . ASP A 1 87 ? 25.928 12.918 24.184 1.00 52.60 ? 87 ASP A O 1 ATOM 642 C CB . ASP A 1 87 ? 28.366 15.205 23.016 1.00 54.56 ? 87 ASP A CB 1 ATOM 643 C CG . ASP A 1 87 ? 29.260 14.811 24.210 1.00 57.43 ? 87 ASP A CG 1 ATOM 644 O OD1 . ASP A 1 87 ? 29.490 13.585 24.399 1.00 60.77 ? 87 ASP A OD1 1 ATOM 645 O OD2 . ASP A 1 87 ? 29.780 15.734 24.906 1.00 60.12 ? 87 ASP A OD2 1 ATOM 646 N N . GLY A 1 88 ? 26.708 12.845 22.058 1.00 51.06 ? 88 GLY A N 1 ATOM 647 C CA . GLY A 1 88 ? 26.191 11.504 21.772 1.00 49.64 ? 88 GLY A CA 1 ATOM 648 C C . GLY A 1 88 ? 24.668 11.522 21.814 1.00 48.45 ? 88 GLY A C 1 ATOM 649 O O . GLY A 1 88 ? 24.039 12.487 21.342 1.00 48.11 ? 88 GLY A O 1 ATOM 650 N N . LYS A 1 89 ? 24.087 10.476 22.417 1.00 47.52 ? 89 LYS A N 1 ATOM 651 C CA . LYS A 1 89 ? 22.625 10.349 22.622 1.00 46.02 ? 89 LYS A CA 1 ATOM 652 C C . LYS A 1 89 ? 21.928 11.577 23.267 1.00 44.61 ? 89 LYS A C 1 ATOM 653 O O . LYS A 1 89 ? 20.706 11.728 23.176 1.00 44.13 ? 89 LYS A O 1 ATOM 654 C CB . LYS A 1 89 ? 22.296 9.045 23.384 1.00 46.63 ? 89 LYS A CB 1 ATOM 655 C CG . LYS A 1 89 ? 23.098 8.794 24.691 1.00 47.28 ? 89 LYS A CG 1 ATOM 656 C CD . LYS A 1 89 ? 22.892 7.367 25.212 1.00 51.70 ? 89 LYS A CD 1 ATOM 657 C CE . LYS A 1 89 ? 23.706 7.130 26.520 1.00 55.53 ? 89 LYS A CE 1 ATOM 658 N NZ . LYS A 1 89 ? 23.556 5.758 27.139 1.00 54.71 ? 89 LYS A NZ 1 ATOM 659 N N . TYR A 1 90 ? 22.717 12.466 23.869 1.00 42.91 ? 90 TYR A N 1 ATOM 660 C CA . TYR A 1 90 ? 22.199 13.634 24.593 1.00 41.35 ? 90 TYR A CA 1 ATOM 661 C C . TYR A 1 90 ? 22.096 14.877 23.755 1.00 41.19 ? 90 TYR A C 1 ATOM 662 O O . TYR A 1 90 ? 21.553 15.885 24.219 1.00 40.52 ? 90 TYR A O 1 ATOM 663 C CB . TYR A 1 90 ? 23.087 13.969 25.827 1.00 41.10 ? 90 TYR A CB 1 ATOM 664 C CG . TYR A 1 90 ? 23.082 12.883 26.864 1.00 37.72 ? 90 TYR A CG 1 ATOM 665 C CD1 . TYR A 1 90 ? 22.087 12.835 27.843 1.00 36.57 ? 90 TYR A CD1 1 ATOM 666 C CD2 . TYR A 1 90 ? 24.042 11.869 26.838 1.00 35.88 ? 90 TYR A CD2 1 ATOM 667 C CE1 . TYR A 1 90 ? 22.059 11.803 28.811 1.00 33.51 ? 90 TYR A CE1 1 ATOM 668 C CE2 . TYR A 1 90 ? 24.036 10.829 27.802 1.00 35.45 ? 90 TYR A CE2 1 ATOM 669 C CZ . TYR A 1 90 ? 23.028 10.804 28.779 1.00 33.93 ? 90 TYR A CZ 1 ATOM 670 O OH . TYR A 1 90 ? 23.007 9.789 29.711 1.00 31.23 ? 90 TYR A OH 1 ATOM 671 N N . ALA A 1 91 ? 22.636 14.826 22.537 1.00 41.36 ? 91 ALA A N 1 ATOM 672 C CA . ALA A 1 91 ? 22.823 16.058 21.747 1.00 41.57 ? 91 ALA A CA 1 ATOM 673 C C . ALA A 1 91 ? 21.498 16.778 21.499 1.00 41.54 ? 91 ALA A C 1 ATOM 674 O O . ALA A 1 91 ? 21.411 18.025 21.634 1.00 40.32 ? 91 ALA A O 1 ATOM 675 C CB . ALA A 1 91 ? 23.588 15.775 20.432 1.00 41.74 ? 91 ALA A CB 1 ATOM 676 N N . PHE A 1 92 ? 20.465 15.972 21.204 1.00 42.12 ? 92 PHE A N 1 ATOM 677 C CA . PHE A 1 92 ? 19.130 16.476 20.810 1.00 42.89 ? 92 PHE A CA 1 ATOM 678 C C . PHE A 1 92 ? 18.547 17.430 21.838 1.00 43.55 ? 92 PHE A C 1 ATOM 679 O O . PHE A 1 92 ? 17.753 18.334 21.527 1.00 44.10 ? 92 PHE A O 1 ATOM 680 C CB . PHE A 1 92 ? 18.164 15.305 20.562 1.00 43.00 ? 92 PHE A CB 1 ATOM 681 C CG . PHE A 1 92 ? 17.650 14.634 21.834 1.00 41.26 ? 92 PHE A CG 1 ATOM 682 C CD1 . PHE A 1 92 ? 18.343 13.581 22.408 1.00 38.83 ? 92 PHE A CD1 1 ATOM 683 C CD2 . PHE A 1 92 ? 16.453 15.054 22.419 1.00 40.02 ? 92 PHE A CD2 1 ATOM 684 C CE1 . PHE A 1 92 ? 17.862 12.962 23.554 1.00 39.67 ? 92 PHE A CE1 1 ATOM 685 C CE2 . PHE A 1 92 ? 15.962 14.452 23.584 1.00 39.44 ? 92 PHE A CE2 1 ATOM 686 C CZ . PHE A 1 92 ? 16.679 13.398 24.157 1.00 38.44 ? 92 PHE A CZ 1 ATOM 687 N N . LEU A 1 93 ? 18.969 17.228 23.081 1.00 44.72 ? 93 LEU A N 1 ATOM 688 C CA . LEU A 1 93 ? 18.454 17.990 24.203 1.00 45.30 ? 93 LEU A CA 1 ATOM 689 C C . LEU A 1 93 ? 18.809 19.471 24.219 1.00 46.37 ? 93 LEU A C 1 ATOM 690 O O . LEU A 1 93 ? 18.096 20.272 24.842 1.00 46.17 ? 93 LEU A O 1 ATOM 691 C CB . LEU A 1 93 ? 18.867 17.327 25.513 1.00 44.92 ? 93 LEU A CB 1 ATOM 692 C CG . LEU A 1 93 ? 17.820 16.439 26.164 1.00 43.82 ? 93 LEU A CG 1 ATOM 693 C CD1 . LEU A 1 93 ? 18.479 15.763 27.356 1.00 44.00 ? 93 LEU A CD1 1 ATOM 694 C CD2 . LEU A 1 93 ? 16.595 17.239 26.579 1.00 38.85 ? 93 LEU A CD2 1 ATOM 695 N N . LYS A 1 94 ? 19.889 19.850 23.539 1.00 47.91 ? 94 LYS A N 1 ATOM 696 C CA . LYS A 1 94 ? 20.267 21.250 23.545 1.00 49.29 ? 94 LYS A CA 1 ATOM 697 C C . LYS A 1 94 ? 19.149 22.101 22.958 1.00 49.65 ? 94 LYS A C 1 ATOM 698 O O . LYS A 1 94 ? 18.837 23.170 23.493 1.00 49.77 ? 94 LYS A O 1 ATOM 699 C CB . LYS A 1 94 ? 21.602 21.505 22.827 1.00 49.99 ? 94 LYS A CB 1 ATOM 700 C CG . LYS A 1 94 ? 22.159 22.913 23.150 1.00 52.75 ? 94 LYS A CG 1 ATOM 701 C CD . LYS A 1 94 ? 23.576 23.183 22.595 1.00 58.57 ? 94 LYS A CD 1 ATOM 702 C CE . LYS A 1 94 ? 23.977 24.661 22.856 1.00 60.42 ? 94 LYS A CE 1 ATOM 703 N NZ . LYS A 1 94 ? 25.443 24.813 23.186 1.00 62.02 ? 94 LYS A NZ 1 ATOM 704 N N . THR A 1 95 ? 18.540 21.602 21.879 1.00 50.20 ? 95 THR A N 1 ATOM 705 C CA . THR A 1 95 ? 17.610 22.382 21.040 1.00 50.45 ? 95 THR A CA 1 ATOM 706 C C . THR A 1 95 ? 16.158 21.958 21.203 1.00 49.97 ? 95 THR A C 1 ATOM 707 O O . THR A 1 95 ? 15.252 22.665 20.723 1.00 50.42 ? 95 THR A O 1 ATOM 708 C CB . THR A 1 95 ? 17.952 22.255 19.521 1.00 50.78 ? 95 THR A CB 1 ATOM 709 O OG1 . THR A 1 95 ? 18.481 20.940 19.249 1.00 51.30 ? 95 THR A OG1 1 ATOM 710 C CG2 . THR A 1 95 ? 18.973 23.345 19.102 1.00 51.05 ? 95 THR A CG2 1 ATOM 711 N N . TYR A 1 96 ? 15.935 20.815 21.866 1.00 48.68 ? 96 TYR A N 1 ATOM 712 C CA . TYR A 1 96 ? 14.584 20.250 21.958 1.00 46.83 ? 96 TYR A CA 1 ATOM 713 C C . TYR A 1 96 ? 13.610 21.339 22.350 1.00 46.81 ? 96 TYR A C 1 ATOM 714 O O . TYR A 1 96 ? 13.881 22.128 23.262 1.00 45.90 ? 96 TYR A O 1 ATOM 715 C CB . TYR A 1 96 ? 14.492 19.051 22.916 1.00 46.42 ? 96 TYR A CB 1 ATOM 716 C CG . TYR A 1 96 ? 13.099 18.436 22.916 1.00 43.49 ? 96 TYR A CG 1 ATOM 717 C CD1 . TYR A 1 96 ? 12.798 17.374 22.076 1.00 41.23 ? 96 TYR A CD1 1 ATOM 718 C CD2 . TYR A 1 96 ? 12.067 18.958 23.726 1.00 40.04 ? 96 TYR A CD2 1 ATOM 719 C CE1 . TYR A 1 96 ? 11.508 16.816 22.061 1.00 40.98 ? 96 TYR A CE1 1 ATOM 720 C CE2 . TYR A 1 96 ? 10.804 18.415 23.718 1.00 38.99 ? 96 TYR A CE2 1 ATOM 721 C CZ . TYR A 1 96 ? 10.528 17.342 22.882 1.00 39.33 ? 96 TYR A CZ 1 ATOM 722 O OH . TYR A 1 96 ? 9.266 16.783 22.843 1.00 39.83 ? 96 TYR A OH 1 ATOM 723 N N . ASN A 1 97 ? 12.487 21.394 21.630 1.00 46.91 ? 97 ASN A N 1 ATOM 724 C CA . ASN A 1 97 ? 11.550 22.497 21.764 1.00 46.92 ? 97 ASN A CA 1 ATOM 725 C C . ASN A 1 97 ? 10.198 21.938 22.127 1.00 46.19 ? 97 ASN A C 1 ATOM 726 O O . ASN A 1 97 ? 9.444 21.414 21.276 1.00 46.64 ? 97 ASN A O 1 ATOM 727 C CB . ASN A 1 97 ? 11.484 23.296 20.463 1.00 48.01 ? 97 ASN A CB 1 ATOM 728 C CG . ASN A 1 97 ? 10.818 24.641 20.630 1.00 50.98 ? 97 ASN A CG 1 ATOM 729 O OD1 . ASN A 1 97 ? 9.976 24.847 21.516 1.00 53.33 ? 97 ASN A OD1 1 ATOM 730 N ND2 . ASN A 1 97 ? 11.178 25.575 19.746 1.00 55.99 ? 97 ASN A ND2 1 ATOM 731 N N . TYR A 1 98 ? 9.892 22.042 23.412 1.00 44.53 ? 98 TYR A N 1 ATOM 732 C CA . TYR A 1 98 ? 8.694 21.432 23.944 1.00 42.11 ? 98 TYR A CA 1 ATOM 733 C C . TYR A 1 98 ? 7.485 22.110 23.345 1.00 41.09 ? 98 TYR A C 1 ATOM 734 O O . TYR A 1 98 ? 7.246 23.294 23.583 1.00 40.33 ? 98 TYR A O 1 ATOM 735 C CB . TYR A 1 98 ? 8.651 21.510 25.468 1.00 40.93 ? 98 TYR A CB 1 ATOM 736 C CG . TYR A 1 98 ? 7.573 20.639 26.060 1.00 37.66 ? 98 TYR A CG 1 ATOM 737 C CD1 . TYR A 1 98 ? 6.270 21.123 26.202 1.00 36.59 ? 98 TYR A CD1 1 ATOM 738 C CD2 . TYR A 1 98 ? 7.843 19.336 26.496 1.00 34.07 ? 98 TYR A CD2 1 ATOM 739 C CE1 . TYR A 1 98 ? 5.278 20.345 26.753 1.00 34.78 ? 98 TYR A CE1 1 ATOM 740 C CE2 . TYR A 1 98 ? 6.844 18.550 27.068 1.00 30.52 ? 98 TYR A CE2 1 ATOM 741 C CZ . TYR A 1 98 ? 5.572 19.059 27.184 1.00 31.20 ? 98 TYR A CZ 1 ATOM 742 O OH . TYR A 1 98 ? 4.538 18.332 27.729 1.00 30.70 ? 98 TYR A OH 1 ATOM 743 N N . SER A 1 99 ? 6.724 21.335 22.577 1.00 40.23 ? 99 SER A N 1 ATOM 744 C CA . SER A 1 99 ? 5.518 21.864 21.967 1.00 39.54 ? 99 SER A CA 1 ATOM 745 C C . SER A 1 99 ? 4.348 20.881 21.962 1.00 39.04 ? 99 SER A C 1 ATOM 746 O O . SER A 1 99 ? 3.382 21.070 21.191 1.00 39.09 ? 99 SER A O 1 ATOM 747 C CB . SER A 1 99 ? 5.817 22.392 20.559 1.00 40.10 ? 99 SER A CB 1 ATOM 748 O OG . SER A 1 99 ? 6.296 21.344 19.764 1.00 37.97 ? 99 SER A OG 1 ATOM 749 N N . LEU A 1 100 ? 4.430 19.861 22.831 1.00 36.75 ? 100 LEU A N 1 ATOM 750 C CA . LEU A 1 100 ? 3.296 18.994 23.129 1.00 35.16 ? 100 LEU A CA 1 ATOM 751 C C . LEU A 1 100 ? 2.064 19.795 23.538 1.00 33.95 ? 100 LEU A C 1 ATOM 752 O O . LEU A 1 100 ? 2.175 20.823 24.206 1.00 33.97 ? 100 LEU A O 1 ATOM 753 C CB . LEU A 1 100 ? 3.639 17.980 24.233 1.00 34.04 ? 100 LEU A CB 1 ATOM 754 C CG . LEU A 1 100 ? 4.760 16.988 23.923 1.00 35.00 ? 100 LEU A CG 1 ATOM 755 C CD1 . LEU A 1 100 ? 4.895 15.940 25.039 1.00 33.29 ? 100 LEU A CD1 1 ATOM 756 C CD2 . LEU A 1 100 ? 4.532 16.288 22.579 1.00 35.57 ? 100 LEU A CD2 1 ATOM 757 N N . GLY A 1 101 ? 0.880 19.327 23.138 1.00 32.81 ? 101 GLY A N 1 ATOM 758 C CA . GLY A 1 101 ? -0.343 19.893 23.664 1.00 30.39 ? 101 GLY A CA 1 ATOM 759 C C . GLY A 1 101 ? -0.647 19.261 25.012 1.00 30.57 ? 101 GLY A C 1 ATOM 760 O O . GLY A 1 101 ? 0.204 18.559 25.579 1.00 29.53 ? 101 GLY A O 1 ATOM 761 N N . ALA A 1 102 ? -1.879 19.455 25.497 1.00 29.45 ? 102 ALA A N 1 ATOM 762 C CA . ALA A 1 102 ? -2.244 19.129 26.858 1.00 29.60 ? 102 ALA A CA 1 ATOM 763 C C . ALA A 1 102 ? -3.651 18.500 26.976 1.00 29.97 ? 102 ALA A C 1 ATOM 764 O O . ALA A 1 102 ? -4.647 19.039 26.425 1.00 29.43 ? 102 ALA A O 1 ATOM 765 C CB . ALA A 1 102 ? -2.177 20.403 27.708 1.00 30.29 ? 102 ALA A CB 1 ATOM 766 N N . ASP A 1 103 ? -3.720 17.378 27.702 1.00 29.05 ? 103 ASP A N 1 ATOM 767 C CA . ASP A 1 103 ? -4.980 16.645 28.003 1.00 29.63 ? 103 ASP A CA 1 ATOM 768 C C . ASP A 1 103 ? -5.663 15.888 26.837 1.00 29.56 ? 103 ASP A C 1 ATOM 769 O O . ASP A 1 103 ? -6.130 14.760 27.012 1.00 29.50 ? 103 ASP A O 1 ATOM 770 C CB . ASP A 1 103 ? -5.996 17.554 28.709 1.00 29.97 ? 103 ASP A CB 1 ATOM 771 C CG . ASP A 1 103 ? -5.488 18.055 30.079 1.00 32.94 ? 103 ASP A CG 1 ATOM 772 O OD1 . ASP A 1 103 ? -5.283 17.227 30.986 1.00 34.56 ? 103 ASP A OD1 1 ATOM 773 O OD2 . ASP A 1 103 ? -5.291 19.274 30.238 1.00 35.92 ? 103 ASP A OD2 1 ATOM 774 N N . ASP A 1 104 ? -5.709 16.529 25.669 1.00 29.01 ? 104 ASP A N 1 ATOM 775 C CA . ASP A 1 104 ? -6.479 16.100 24.516 1.00 29.21 ? 104 ASP A CA 1 ATOM 776 C C . ASP A 1 104 ? -5.839 14.860 23.894 1.00 27.84 ? 104 ASP A C 1 ATOM 777 O O . ASP A 1 104 ? -4.651 14.632 24.058 1.00 27.63 ? 104 ASP A O 1 ATOM 778 C CB . ASP A 1 104 ? -6.514 17.226 23.437 1.00 29.51 ? 104 ASP A CB 1 ATOM 779 C CG . ASP A 1 104 ? -6.943 18.628 23.995 1.00 34.05 ? 104 ASP A CG 1 ATOM 780 O OD1 . ASP A 1 104 ? -7.725 18.688 25.003 1.00 36.16 ? 104 ASP A OD1 1 ATOM 781 O OD2 . ASP A 1 104 ? -6.504 19.673 23.390 1.00 34.84 ? 104 ASP A OD2 1 ATOM 782 N N . LEU A 1 105 ? -6.638 14.080 23.178 1.00 26.06 ? 105 LEU A N 1 ATOM 783 C CA . LEU A 1 105 ? -6.159 13.027 22.302 1.00 25.67 ? 105 LEU A CA 1 ATOM 784 C C . LEU A 1 105 ? -5.157 13.536 21.243 1.00 25.68 ? 105 LEU A C 1 ATOM 785 O O . LEU A 1 105 ? -5.310 14.622 20.695 1.00 26.89 ? 105 LEU A O 1 ATOM 786 C CB . LEU A 1 105 ? -7.377 12.493 21.572 1.00 25.16 ? 105 LEU A CB 1 ATOM 787 C CG . LEU A 1 105 ? -8.068 11.152 21.734 1.00 24.62 ? 105 LEU A CG 1 ATOM 788 C CD1 . LEU A 1 105 ? -7.752 10.415 23.044 1.00 24.98 ? 105 LEU A CD1 1 ATOM 789 C CD2 . LEU A 1 105 ? -9.541 11.328 21.456 1.00 20.44 ? 105 LEU A CD2 1 ATOM 790 N N . THR A 1 106 ? -4.132 12.767 20.939 1.00 25.56 ? 106 THR A N 1 ATOM 791 C CA . THR A 1 106 ? -3.285 13.084 19.797 1.00 25.81 ? 106 THR A CA 1 ATOM 792 C C . THR A 1 106 ? -3.917 12.509 18.481 1.00 26.74 ? 106 THR A C 1 ATOM 793 O O . THR A 1 106 ? -4.852 11.710 18.559 1.00 27.62 ? 106 THR A O 1 ATOM 794 C CB . THR A 1 106 ? -1.947 12.463 19.995 1.00 25.29 ? 106 THR A CB 1 ATOM 795 O OG1 . THR A 1 106 ? -2.088 11.023 19.886 1.00 26.05 ? 106 THR A OG1 1 ATOM 796 C CG2 . THR A 1 106 ? -1.391 12.881 21.397 1.00 21.17 ? 106 THR A CG2 1 ATOM 797 N N . PRO A 1 107 ? -3.468 12.978 17.289 1.00 26.99 ? 107 PRO A N 1 ATOM 798 C CA . PRO A 1 107 ? -3.882 12.339 16.009 1.00 25.88 ? 107 PRO A CA 1 ATOM 799 C C . PRO A 1 107 ? -3.752 10.824 16.093 1.00 24.65 ? 107 PRO A C 1 ATOM 800 O O . PRO A 1 107 ? -4.701 10.089 15.800 1.00 25.16 ? 107 PRO A O 1 ATOM 801 C CB . PRO A 1 107 ? -2.869 12.919 14.994 1.00 26.35 ? 107 PRO A CB 1 ATOM 802 C CG . PRO A 1 107 ? -2.742 14.416 15.493 1.00 28.40 ? 107 PRO A CG 1 ATOM 803 C CD . PRO A 1 107 ? -2.875 14.327 17.062 1.00 26.34 ? 107 PRO A CD 1 ATOM 804 N N . PHE A 1 108 ? -2.610 10.359 16.536 1.00 23.03 ? 108 PHE A N 1 ATOM 805 C CA . PHE A 1 108 ? -2.428 8.915 16.748 1.00 22.08 ? 108 PHE A CA 1 ATOM 806 C C . PHE A 1 108 ? -3.511 8.276 17.660 1.00 21.82 ? 108 PHE A C 1 ATOM 807 O O . PHE A 1 108 ? -4.026 7.207 17.372 1.00 21.27 ? 108 PHE A O 1 ATOM 808 C CB . PHE A 1 108 ? -1.037 8.640 17.320 1.00 20.81 ? 108 PHE A CB 1 ATOM 809 C CG . PHE A 1 108 ? -0.805 7.209 17.612 1.00 20.98 ? 108 PHE A CG 1 ATOM 810 C CD1 . PHE A 1 108 ? -0.558 6.326 16.597 1.00 18.59 ? 108 PHE A CD1 1 ATOM 811 C CD2 . PHE A 1 108 ? -0.831 6.740 18.901 1.00 21.79 ? 108 PHE A CD2 1 ATOM 812 C CE1 . PHE A 1 108 ? -0.385 4.973 16.857 1.00 21.91 ? 108 PHE A CE1 1 ATOM 813 C CE2 . PHE A 1 108 ? -0.631 5.397 19.176 1.00 23.67 ? 108 PHE A CE2 1 ATOM 814 C CZ . PHE A 1 108 ? -0.431 4.503 18.140 1.00 22.56 ? 108 PHE A CZ 1 ATOM 815 N N . GLY A 1 109 ? -3.846 8.928 18.765 1.00 22.27 ? 109 GLY A N 1 ATOM 816 C CA . GLY A 1 109 ? -4.862 8.401 19.689 1.00 22.10 ? 109 GLY A CA 1 ATOM 817 C C . GLY A 1 109 ? -6.221 8.368 19.039 1.00 22.56 ? 109 GLY A C 1 ATOM 818 O O . GLY A 1 109 ? -6.991 7.496 19.289 1.00 23.54 ? 109 GLY A O 1 ATOM 819 N N . GLU A 1 110 ? -6.544 9.362 18.235 1.00 22.77 ? 110 GLU A N 1 ATOM 820 C CA . GLU A 1 110 ? -7.801 9.376 17.493 1.00 22.10 ? 110 GLU A CA 1 ATOM 821 C C . GLU A 1 110 ? -7.936 8.146 16.603 1.00 20.91 ? 110 GLU A C 1 ATOM 822 O O . GLU A 1 110 ? -8.927 7.421 16.667 1.00 21.21 ? 110 GLU A O 1 ATOM 823 C CB . GLU A 1 110 ? -7.881 10.668 16.682 1.00 22.92 ? 110 GLU A CB 1 ATOM 824 C CG . GLU A 1 110 ? -8.204 11.871 17.562 1.00 25.59 ? 110 GLU A CG 1 ATOM 825 C CD . GLU A 1 110 ? -8.150 13.195 16.805 1.00 27.30 ? 110 GLU A CD 1 ATOM 826 O OE1 . GLU A 1 110 ? -7.642 13.246 15.691 1.00 30.34 ? 110 GLU A OE1 1 ATOM 827 O OE2 . GLU A 1 110 ? -8.604 14.196 17.335 1.00 29.85 ? 110 GLU A OE2 1 ATOM 828 N N . GLN A 1 111 ? -6.897 7.873 15.833 1.00 19.91 ? 111 GLN A N 1 ATOM 829 C CA . GLN A 1 111 ? -6.861 6.767 14.952 1.00 19.92 ? 111 GLN A CA 1 ATOM 830 C C . GLN A 1 111 ? -6.922 5.422 15.669 1.00 20.20 ? 111 GLN A C 1 ATOM 831 O O . GLN A 1 111 ? -7.495 4.440 15.142 1.00 20.47 ? 111 GLN A O 1 ATOM 832 C CB . GLN A 1 111 ? -5.586 6.885 14.082 1.00 20.86 ? 111 GLN A CB 1 ATOM 833 C CG . GLN A 1 111 ? -5.557 5.850 12.983 1.00 22.33 ? 111 GLN A CG 1 ATOM 834 C CD . GLN A 1 111 ? -6.710 6.036 11.966 1.00 25.27 ? 111 GLN A CD 1 ATOM 835 O OE1 . GLN A 1 111 ? -6.902 7.125 11.438 1.00 31.37 ? 111 GLN A OE1 1 ATOM 836 N NE2 . GLN A 1 111 ? -7.423 4.980 11.667 1.00 21.71 ? 111 GLN A NE2 1 ATOM 837 N N . GLU A 1 112 ? -6.326 5.325 16.851 1.00 19.28 ? 112 GLU A N 1 ATOM 838 C CA . GLU A 1 112 ? -6.413 4.056 17.591 1.00 19.96 ? 112 GLU A CA 1 ATOM 839 C C . GLU A 1 112 ? -7.902 3.714 17.841 1.00 19.78 ? 112 GLU A C 1 ATOM 840 O O . GLU A 1 112 ? -8.296 2.530 17.891 1.00 18.97 ? 112 GLU A O 1 ATOM 841 C CB . GLU A 1 112 ? -5.694 4.122 18.978 1.00 19.25 ? 112 GLU A CB 1 ATOM 842 C CG . GLU A 1 112 ? -4.142 4.066 18.982 1.00 19.33 ? 112 GLU A CG 1 ATOM 843 C CD . GLU A 1 112 ? -3.603 4.166 20.432 1.00 23.68 ? 112 GLU A CD 1 ATOM 844 O OE1 . GLU A 1 112 ? -3.921 5.186 21.068 1.00 20.76 ? 112 GLU A OE1 1 ATOM 845 O OE2 . GLU A 1 112 ? -2.912 3.221 20.926 1.00 22.35 ? 112 GLU A OE2 1 ATOM 846 N N . LEU A 1 113 ? -8.711 4.725 18.080 1.00 19.36 ? 113 LEU A N 1 ATOM 847 C CA . LEU A 1 113 ? -10.049 4.391 18.518 1.00 20.20 ? 113 LEU A CA 1 ATOM 848 C C . LEU A 1 113 ? -10.902 4.179 17.313 1.00 20.95 ? 113 LEU A C 1 ATOM 849 O O . LEU A 1 113 ? -11.894 3.460 17.403 1.00 22.31 ? 113 LEU A O 1 ATOM 850 C CB . LEU A 1 113 ? -10.630 5.459 19.458 1.00 20.82 ? 113 LEU A CB 1 ATOM 851 C CG . LEU A 1 113 ? -10.399 5.372 20.988 1.00 20.89 ? 113 LEU A CG 1 ATOM 852 C CD1 . LEU A 1 113 ? -11.447 4.495 21.698 1.00 19.04 ? 113 LEU A CD1 1 ATOM 853 C CD2 . LEU A 1 113 ? -9.004 4.902 21.315 1.00 18.10 ? 113 LEU A CD2 1 ATOM 854 N N . VAL A 1 114 ? -10.516 4.789 16.176 1.00 21.01 ? 114 VAL A N 1 ATOM 855 C CA . VAL A 1 114 ? -11.205 4.554 14.915 1.00 20.26 ? 114 VAL A CA 1 ATOM 856 C C . VAL A 1 114 ? -10.950 3.072 14.606 1.00 20.25 ? 114 VAL A C 1 ATOM 857 O O . VAL A 1 114 ? -11.895 2.306 14.339 1.00 19.70 ? 114 VAL A O 1 ATOM 858 C CB . VAL A 1 114 ? -10.673 5.450 13.773 1.00 20.72 ? 114 VAL A CB 1 ATOM 859 C CG1 . VAL A 1 114 ? -11.074 4.850 12.364 1.00 19.42 ? 114 VAL A CG1 1 ATOM 860 C CG2 . VAL A 1 114 ? -11.193 6.848 13.939 1.00 19.39 ? 114 VAL A CG2 1 ATOM 861 N N . ASN A 1 115 ? -9.670 2.673 14.714 1.00 19.14 ? 115 ASN A N 1 ATOM 862 C CA . ASN A 1 115 ? -9.291 1.312 14.499 1.00 18.94 ? 115 ASN A CA 1 ATOM 863 C C . ASN A 1 115 ? -10.018 0.361 15.433 1.00 18.32 ? 115 ASN A C 1 ATOM 864 O O . ASN A 1 115 ? -10.405 -0.758 15.072 1.00 18.07 ? 115 ASN A O 1 ATOM 865 C CB . ASN A 1 115 ? -7.772 1.123 14.598 1.00 18.66 ? 115 ASN A CB 1 ATOM 866 C CG . ASN A 1 115 ? -7.053 1.851 13.499 1.00 21.17 ? 115 ASN A CG 1 ATOM 867 O OD1 . ASN A 1 115 ? -7.697 2.481 12.647 1.00 18.32 ? 115 ASN A OD1 1 ATOM 868 N ND2 . ASN A 1 115 ? -5.734 1.809 13.512 1.00 22.08 ? 115 ASN A ND2 1 ATOM 869 N N . SER A 1 116 ? -10.145 0.780 16.662 1.00 18.14 ? 116 SER A N 1 ATOM 870 C CA . SER A 1 116 ? -10.816 -0.062 17.599 1.00 18.40 ? 116 SER A CA 1 ATOM 871 C C . SER A 1 116 ? -12.288 -0.241 17.179 1.00 17.40 ? 116 SER A C 1 ATOM 872 O O . SER A 1 116 ? -12.803 -1.322 17.335 1.00 17.69 ? 116 SER A O 1 ATOM 873 C CB . SER A 1 116 ? -10.708 0.493 19.026 1.00 17.68 ? 116 SER A CB 1 ATOM 874 O OG . SER A 1 116 ? -11.386 -0.384 19.918 1.00 16.68 ? 116 SER A OG 1 ATOM 875 N N . GLY A 1 117 ? -12.947 0.799 16.664 1.00 17.06 ? 117 GLY A N 1 ATOM 876 C CA . GLY A 1 117 ? -14.344 0.660 16.189 1.00 16.98 ? 117 GLY A CA 1 ATOM 877 C C . GLY A 1 117 ? -14.490 -0.330 15.009 1.00 17.28 ? 117 GLY A C 1 ATOM 878 O O . GLY A 1 117 ? -15.434 -1.126 14.949 1.00 16.54 ? 117 GLY A O 1 ATOM 879 N N . ILE A 1 118 ? -13.508 -0.292 14.114 1.00 16.89 ? 118 ILE A N 1 ATOM 880 C CA . ILE A 1 118 ? -13.437 -1.125 12.973 1.00 17.82 ? 118 ILE A CA 1 ATOM 881 C C . ILE A 1 118 ? -13.316 -2.544 13.448 1.00 19.30 ? 118 ILE A C 1 ATOM 882 O O . ILE A 1 118 ? -14.082 -3.439 13.032 1.00 18.77 ? 118 ILE A O 1 ATOM 883 C CB . ILE A 1 118 ? -12.204 -0.743 12.068 1.00 18.38 ? 118 ILE A CB 1 ATOM 884 C CG1 . ILE A 1 118 ? -12.337 0.696 11.561 1.00 16.38 ? 118 ILE A CG1 1 ATOM 885 C CG2 . ILE A 1 118 ? -12.098 -1.715 10.922 1.00 17.08 ? 118 ILE A CG2 1 ATOM 886 C CD1 . ILE A 1 118 ? -11.223 1.125 10.589 1.00 20.15 ? 118 ILE A CD1 1 ATOM 887 N N . LYS A 1 119 ? -12.351 -2.749 14.345 1.00 19.61 ? 119 LYS A N 1 ATOM 888 C CA . LYS A 1 119 ? -12.129 -4.077 14.857 1.00 19.85 ? 119 LYS A CA 1 ATOM 889 C C . LYS A 1 119 ? -13.370 -4.620 15.592 1.00 18.93 ? 119 LYS A C 1 ATOM 890 O O . LYS A 1 119 ? -13.744 -5.756 15.387 1.00 19.93 ? 119 LYS A O 1 ATOM 891 C CB . LYS A 1 119 ? -10.841 -4.130 15.699 1.00 20.47 ? 119 LYS A CB 1 ATOM 892 C CG . LYS A 1 119 ? -10.475 -5.514 16.120 1.00 22.33 ? 119 LYS A CG 1 ATOM 893 C CD . LYS A 1 119 ? -8.999 -5.687 16.293 1.00 23.92 ? 119 LYS A CD 1 ATOM 894 C CE . LYS A 1 119 ? -8.728 -7.073 16.865 1.00 24.29 ? 119 LYS A CE 1 ATOM 895 N NZ . LYS A 1 119 ? -7.338 -7.197 17.360 1.00 23.33 ? 119 LYS A NZ 1 ATOM 896 N N . PHE A 1 120 ? -14.012 -3.832 16.427 1.00 17.26 ? 120 PHE A N 1 ATOM 897 C CA . PHE A 1 120 ? -15.204 -4.356 17.150 1.00 17.41 ? 120 PHE A CA 1 ATOM 898 C C . PHE A 1 120 ? -16.339 -4.677 16.143 1.00 17.90 ? 120 PHE A C 1 ATOM 899 O O . PHE A 1 120 ? -16.976 -5.707 16.267 1.00 17.17 ? 120 PHE A O 1 ATOM 900 C CB . PHE A 1 120 ? -15.699 -3.344 18.161 1.00 15.94 ? 120 PHE A CB 1 ATOM 901 C CG . PHE A 1 120 ? -16.881 -3.792 18.960 1.00 13.65 ? 120 PHE A CG 1 ATOM 902 C CD1 . PHE A 1 120 ? -16.732 -4.636 20.041 1.00 15.00 ? 120 PHE A CD1 1 ATOM 903 C CD2 . PHE A 1 120 ? -18.136 -3.326 18.682 1.00 14.67 ? 120 PHE A CD2 1 ATOM 904 C CE1 . PHE A 1 120 ? -17.841 -5.051 20.834 1.00 15.01 ? 120 PHE A CE1 1 ATOM 905 C CE2 . PHE A 1 120 ? -19.278 -3.718 19.463 1.00 17.19 ? 120 PHE A CE2 1 ATOM 906 C CZ . PHE A 1 120 ? -19.095 -4.586 20.559 1.00 15.83 ? 120 PHE A CZ 1 ATOM 907 N N . TYR A 1 121 ? -16.547 -3.785 15.152 1.00 17.50 ? 121 TYR A N 1 ATOM 908 C CA . TYR A 1 121 ? -17.551 -4.001 14.109 1.00 18.83 ? 121 TYR A CA 1 ATOM 909 C C . TYR A 1 121 ? -17.318 -5.330 13.378 1.00 18.41 ? 121 TYR A C 1 ATOM 910 O O . TYR A 1 121 ? -18.239 -6.086 13.212 1.00 16.87 ? 121 TYR A O 1 ATOM 911 C CB . TYR A 1 121 ? -17.667 -2.814 13.081 1.00 18.60 ? 121 TYR A CB 1 ATOM 912 C CG . TYR A 1 121 ? -18.783 -3.116 12.105 1.00 20.08 ? 121 TYR A CG 1 ATOM 913 C CD1 . TYR A 1 121 ? -18.572 -3.972 11.007 1.00 18.46 ? 121 TYR A CD1 1 ATOM 914 C CD2 . TYR A 1 121 ? -20.073 -2.645 12.345 1.00 18.46 ? 121 TYR A CD2 1 ATOM 915 C CE1 . TYR A 1 121 ? -19.614 -4.322 10.132 1.00 16.02 ? 121 TYR A CE1 1 ATOM 916 C CE2 . TYR A 1 121 ? -21.109 -2.986 11.509 1.00 18.79 ? 121 TYR A CE2 1 ATOM 917 C CZ . TYR A 1 121 ? -20.877 -3.824 10.405 1.00 18.59 ? 121 TYR A CZ 1 ATOM 918 O OH . TYR A 1 121 ? -21.928 -4.097 9.587 1.00 19.07 ? 121 TYR A OH 1 ATOM 919 N N . GLN A 1 122 ? -16.063 -5.588 12.975 1.00 19.24 ? 122 GLN A N 1 ATOM 920 C CA . GLN A 1 122 ? -15.716 -6.773 12.224 1.00 20.44 ? 122 GLN A CA 1 ATOM 921 C C . GLN A 1 122 ? -15.794 -8.024 13.064 1.00 21.19 ? 122 GLN A C 1 ATOM 922 O O . GLN A 1 122 ? -16.349 -9.021 12.625 1.00 21.60 ? 122 GLN A O 1 ATOM 923 C CB . GLN A 1 122 ? -14.317 -6.664 11.610 1.00 21.35 ? 122 GLN A CB 1 ATOM 924 C CG . GLN A 1 122 ? -14.191 -5.481 10.744 1.00 25.14 ? 122 GLN A CG 1 ATOM 925 C CD . GLN A 1 122 ? -12.946 -5.513 9.889 1.00 34.96 ? 122 GLN A CD 1 ATOM 926 O OE1 . GLN A 1 122 ? -11.814 -5.704 10.379 1.00 37.49 ? 122 GLN A OE1 1 ATOM 927 N NE2 . GLN A 1 122 ? -13.142 -5.290 8.583 1.00 38.13 ? 122 GLN A NE2 1 ATOM 928 N N . ARG A 1 123 ? -15.226 -8.007 14.255 1.00 20.90 ? 123 ARG A N 1 ATOM 929 C CA . ARG A 1 123 ? -15.223 -9.214 15.077 1.00 21.11 ? 123 ARG A CA 1 ATOM 930 C C . ARG A 1 123 ? -16.662 -9.697 15.382 1.00 20.28 ? 123 ARG A C 1 ATOM 931 O O . ARG A 1 123 ? -16.935 -10.900 15.481 1.00 19.01 ? 123 ARG A O 1 ATOM 932 C CB . ARG A 1 123 ? -14.435 -8.946 16.388 1.00 21.13 ? 123 ARG A CB 1 ATOM 933 C CG . ARG A 1 123 ? -14.532 -10.058 17.452 1.00 22.76 ? 123 ARG A CG 1 ATOM 934 C CD . ARG A 1 123 ? -13.571 -9.837 18.670 1.00 23.39 ? 123 ARG A CD 1 ATOM 935 N NE . ARG A 1 123 ? -13.719 -10.976 19.573 1.00 22.48 ? 123 ARG A NE 1 ATOM 936 C CZ . ARG A 1 123 ? -12.967 -12.084 19.570 1.00 21.82 ? 123 ARG A CZ 1 ATOM 937 N NH1 . ARG A 1 123 ? -11.898 -12.232 18.781 1.00 19.43 ? 123 ARG A NH1 1 ATOM 938 N NH2 . ARG A 1 123 ? -13.282 -13.047 20.402 1.00 16.63 ? 123 ARG A NH2 1 ATOM 939 N N . TYR A 1 124 ? -17.586 -8.762 15.546 1.00 20.35 ? 124 TYR A N 1 ATOM 940 C CA . TYR A 1 124 ? -18.974 -9.154 15.913 1.00 20.77 ? 124 TYR A CA 1 ATOM 941 C C . TYR A 1 124 ? -20.012 -8.822 14.769 1.00 21.64 ? 124 TYR A C 1 ATOM 942 O O . TYR A 1 124 ? -21.249 -8.625 15.009 1.00 19.69 ? 124 TYR A O 1 ATOM 943 C CB . TYR A 1 124 ? -19.369 -8.558 17.278 1.00 19.62 ? 124 TYR A CB 1 ATOM 944 C CG . TYR A 1 124 ? -18.411 -8.952 18.381 1.00 21.74 ? 124 TYR A CG 1 ATOM 945 C CD1 . TYR A 1 124 ? -18.367 -10.267 18.858 1.00 19.73 ? 124 TYR A CD1 1 ATOM 946 C CD2 . TYR A 1 124 ? -17.561 -7.995 18.976 1.00 18.46 ? 124 TYR A CD2 1 ATOM 947 C CE1 . TYR A 1 124 ? -17.473 -10.634 19.885 1.00 21.29 ? 124 TYR A CE1 1 ATOM 948 C CE2 . TYR A 1 124 ? -16.671 -8.358 19.969 1.00 17.04 ? 124 TYR A CE2 1 ATOM 949 C CZ . TYR A 1 124 ? -16.618 -9.668 20.406 1.00 20.68 ? 124 TYR A CZ 1 ATOM 950 O OH . TYR A 1 124 ? -15.727 -10.013 21.381 1.00 19.68 ? 124 TYR A OH 1 ATOM 951 N N . GLU A 1 125 ? -19.463 -8.801 13.540 1.00 22.16 ? 125 GLU A N 1 ATOM 952 C CA . GLU A 1 125 ? -20.223 -8.461 12.303 1.00 23.46 ? 125 GLU A CA 1 ATOM 953 C C . GLU A 1 125 ? -21.617 -9.139 12.151 1.00 22.58 ? 125 GLU A C 1 ATOM 954 O O . GLU A 1 125 ? -22.554 -8.516 11.631 1.00 22.82 ? 125 GLU A O 1 ATOM 955 C CB . GLU A 1 125 ? -19.343 -8.655 11.037 1.00 22.53 ? 125 GLU A CB 1 ATOM 956 C CG . GLU A 1 125 ? -19.956 -8.071 9.774 1.00 23.62 ? 125 GLU A CG 1 ATOM 957 C CD . GLU A 1 125 ? -20.973 -9.012 9.084 1.00 24.52 ? 125 GLU A CD 1 ATOM 958 O OE1 . GLU A 1 125 ? -20.901 -10.250 9.240 1.00 18.85 ? 125 GLU A OE1 1 ATOM 959 O OE2 . GLU A 1 125 ? -21.843 -8.483 8.379 1.00 24.88 ? 125 GLU A OE2 1 ATOM 960 N N . SER A 1 126 ? -21.754 -10.377 12.625 1.00 22.22 ? 126 SER A N 1 ATOM 961 C CA . SER A 1 126 ? -22.994 -11.087 12.433 1.00 21.80 ? 126 SER A CA 1 ATOM 962 C C . SER A 1 126 ? -24.066 -10.567 13.374 1.00 20.99 ? 126 SER A C 1 ATOM 963 O O . SER A 1 126 ? -25.294 -10.828 13.197 1.00 19.84 ? 126 SER A O 1 ATOM 964 C CB . SER A 1 126 ? -22.786 -12.622 12.334 1.00 23.36 ? 126 SER A CB 1 ATOM 965 O OG . SER A 1 126 ? -22.790 -13.280 13.565 1.00 29.24 ? 126 SER A OG 1 ATOM 966 N N . LEU A 1 127 ? -23.622 -9.663 14.268 1.00 19.55 ? 127 LEU A N 1 ATOM 967 C CA . LEU A 1 127 ? -24.532 -8.836 15.068 1.00 18.22 ? 127 LEU A CA 1 ATOM 968 C C . LEU A 1 127 ? -24.475 -7.341 14.803 1.00 19.30 ? 127 LEU A C 1 ATOM 969 O O . LEU A 1 127 ? -25.504 -6.685 14.940 1.00 20.01 ? 127 LEU A O 1 ATOM 970 C CB . LEU A 1 127 ? -24.299 -9.051 16.574 1.00 17.80 ? 127 LEU A CB 1 ATOM 971 C CG . LEU A 1 127 ? -24.208 -10.533 16.991 1.00 17.68 ? 127 LEU A CG 1 ATOM 972 C CD1 . LEU A 1 127 ? -23.589 -10.574 18.336 1.00 17.02 ? 127 LEU A CD1 1 ATOM 973 C CD2 . LEU A 1 127 ? -25.539 -11.207 16.970 1.00 14.78 ? 127 LEU A CD2 1 ATOM 974 N N . THR A 1 128 ? -23.289 -6.791 14.524 1.00 18.13 ? 128 THR A N 1 ATOM 975 C CA . THR A 1 128 ? -23.109 -5.381 14.292 1.00 18.82 ? 128 THR A CA 1 ATOM 976 C C . THR A 1 128 ? -23.779 -4.927 12.938 1.00 20.77 ? 128 THR A C 1 ATOM 977 O O . THR A 1 128 ? -24.000 -3.725 12.677 1.00 19.44 ? 128 THR A O 1 ATOM 978 C CB . THR A 1 128 ? -21.596 -5.027 14.312 1.00 19.52 ? 128 THR A CB 1 ATOM 979 O OG1 . THR A 1 128 ? -20.861 -5.922 13.440 1.00 19.02 ? 128 THR A OG1 1 ATOM 980 C CG2 . THR A 1 128 ? -21.021 -5.232 15.736 1.00 19.33 ? 128 THR A CG2 1 ATOM 981 N N . ARG A 1 129 ? -24.092 -5.902 12.079 1.00 21.30 ? 129 ARG A N 1 ATOM 982 C CA . ARG A 1 129 ? -24.758 -5.595 10.837 1.00 21.88 ? 129 ARG A CA 1 ATOM 983 C C . ARG A 1 129 ? -26.151 -5.033 10.993 1.00 22.30 ? 129 ARG A C 1 ATOM 984 O O . ARG A 1 129 ? -26.553 -4.156 10.206 1.00 22.10 ? 129 ARG A O 1 ATOM 985 C CB . ARG A 1 129 ? -24.733 -6.789 9.907 1.00 21.58 ? 129 ARG A CB 1 ATOM 986 C CG . ARG A 1 129 ? -25.628 -7.945 10.200 1.00 22.06 ? 129 ARG A CG 1 ATOM 987 C CD . ARG A 1 129 ? -24.800 -9.029 9.555 1.00 25.13 ? 129 ARG A CD 1 ATOM 988 N NE . ARG A 1 129 ? -25.610 -10.095 9.118 1.00 24.66 ? 129 ARG A NE 1 ATOM 989 C CZ . ARG A 1 129 ? -25.142 -11.208 8.566 1.00 24.89 ? 129 ARG A CZ 1 ATOM 990 N NH1 . ARG A 1 129 ? -23.816 -11.432 8.394 1.00 21.92 ? 129 ARG A NH1 1 ATOM 991 N NH2 . ARG A 1 129 ? -26.048 -12.100 8.191 1.00 19.79 ? 129 ARG A NH2 1 ATOM 992 N N . ASN A 1 130 ? -26.855 -5.448 12.036 1.00 22.40 ? 130 ASN A N 1 ATOM 993 C CA . ASN A 1 130 ? -28.210 -4.920 12.217 1.00 23.42 ? 130 ASN A CA 1 ATOM 994 C C . ASN A 1 130 ? -28.588 -4.392 13.631 1.00 23.31 ? 130 ASN A C 1 ATOM 995 O O . ASN A 1 130 ? -29.747 -3.995 13.858 1.00 23.08 ? 130 ASN A O 1 ATOM 996 C CB . ASN A 1 130 ? -29.235 -5.938 11.728 1.00 22.93 ? 130 ASN A CB 1 ATOM 997 C CG . ASN A 1 130 ? -29.159 -7.256 12.475 1.00 24.86 ? 130 ASN A CG 1 ATOM 998 O OD1 . ASN A 1 130 ? -28.457 -7.393 13.463 1.00 24.44 ? 130 ASN A OD1 1 ATOM 999 N ND2 . ASN A 1 130 ? -29.861 -8.258 11.964 1.00 26.61 ? 130 ASN A ND2 1 ATOM 1000 N N . ILE A 1 131 ? -27.624 -4.395 14.560 1.00 23.15 ? 131 ILE A N 1 ATOM 1001 C CA . ILE A 1 131 ? -27.862 -4.001 15.953 1.00 22.29 ? 131 ILE A CA 1 ATOM 1002 C C . ILE A 1 131 ? -27.009 -2.809 16.322 1.00 22.25 ? 131 ILE A C 1 ATOM 1003 O O . ILE A 1 131 ? -25.795 -2.793 16.133 1.00 21.42 ? 131 ILE A O 1 ATOM 1004 C CB . ILE A 1 131 ? -27.679 -5.198 16.956 1.00 23.03 ? 131 ILE A CB 1 ATOM 1005 C CG1 . ILE A 1 131 ? -28.800 -6.229 16.705 1.00 22.08 ? 131 ILE A CG1 1 ATOM 1006 C CG2 . ILE A 1 131 ? -27.834 -4.687 18.389 1.00 20.71 ? 131 ILE A CG2 1 ATOM 1007 C CD1 . ILE A 1 131 ? -28.515 -7.642 17.078 1.00 22.14 ? 131 ILE A CD1 1 ATOM 1008 N N . VAL A 1 132 ? -27.668 -1.774 16.792 1.00 22.11 ? 132 VAL A N 1 ATOM 1009 C CA . VAL A 1 132 ? -26.953 -0.525 17.112 1.00 21.44 ? 132 VAL A CA 1 ATOM 1010 C C . VAL A 1 132 ? -26.592 -0.623 18.574 1.00 20.26 ? 132 VAL A C 1 ATOM 1011 O O . VAL A 1 132 ? -27.487 -0.711 19.387 1.00 19.64 ? 132 VAL A O 1 ATOM 1012 C CB . VAL A 1 132 ? -27.806 0.722 16.836 1.00 21.39 ? 132 VAL A CB 1 ATOM 1013 C CG1 . VAL A 1 132 ? -27.052 1.981 17.234 1.00 20.46 ? 132 VAL A CG1 1 ATOM 1014 C CG2 . VAL A 1 132 ? -28.136 0.787 15.334 1.00 22.84 ? 132 VAL A CG2 1 ATOM 1015 N N . PRO A 1 133 ? -25.284 -0.669 18.896 1.00 19.75 ? 133 PRO A N 1 ATOM 1016 C CA . PRO A 1 133 ? -24.841 -0.774 20.315 1.00 19.88 ? 133 PRO A CA 1 ATOM 1017 C C . PRO A 1 133 ? -25.367 0.369 21.193 1.00 18.23 ? 133 PRO A C 1 ATOM 1018 O O . PRO A 1 133 ? -25.563 1.492 20.711 1.00 17.46 ? 133 PRO A O 1 ATOM 1019 C CB . PRO A 1 133 ? -23.325 -0.679 20.199 1.00 19.58 ? 133 PRO A CB 1 ATOM 1020 C CG . PRO A 1 133 ? -23.031 -1.177 18.764 1.00 20.04 ? 133 PRO A CG 1 ATOM 1021 C CD . PRO A 1 133 ? -24.134 -0.498 17.993 1.00 19.16 ? 133 PRO A CD 1 ATOM 1022 N N . PHE A 1 134 ? -25.679 0.049 22.438 1.00 17.17 ? 134 PHE A N 1 ATOM 1023 C CA . PHE A 1 134 ? -26.019 1.079 23.406 1.00 16.78 ? 134 PHE A CA 1 ATOM 1024 C C . PHE A 1 134 ? -24.695 1.576 24.045 1.00 17.45 ? 134 PHE A C 1 ATOM 1025 O O . PHE A 1 134 ? -23.852 0.776 24.547 1.00 16.58 ? 134 PHE A O 1 ATOM 1026 C CB . PHE A 1 134 ? -27.034 0.625 24.431 1.00 16.38 ? 134 PHE A CB 1 ATOM 1027 C CG . PHE A 1 134 ? -27.433 1.732 25.392 1.00 18.72 ? 134 PHE A CG 1 ATOM 1028 C CD1 . PHE A 1 134 ? -28.437 2.623 25.055 1.00 17.79 ? 134 PHE A CD1 1 ATOM 1029 C CD2 . PHE A 1 134 ? -26.777 1.884 26.617 1.00 20.65 ? 134 PHE A CD2 1 ATOM 1030 C CE1 . PHE A 1 134 ? -28.809 3.647 25.919 1.00 21.28 ? 134 PHE A CE1 1 ATOM 1031 C CE2 . PHE A 1 134 ? -27.133 2.914 27.493 1.00 19.41 ? 134 PHE A CE2 1 ATOM 1032 C CZ . PHE A 1 134 ? -28.149 3.807 27.131 1.00 21.50 ? 134 PHE A CZ 1 ATOM 1033 N N . ILE A 1 135 ? -24.466 2.886 23.959 1.00 17.27 ? 135 ILE A N 1 ATOM 1034 C CA . ILE A 1 135 ? -23.151 3.404 24.285 1.00 17.44 ? 135 ILE A CA 1 ATOM 1035 C C . ILE A 1 135 ? -23.073 4.415 25.420 1.00 17.81 ? 135 ILE A C 1 ATOM 1036 O O . ILE A 1 135 ? -23.821 5.411 25.435 1.00 19.13 ? 135 ILE A O 1 ATOM 1037 C CB . ILE A 1 135 ? -22.480 3.978 23.013 1.00 18.02 ? 135 ILE A CB 1 ATOM 1038 C CG1 . ILE A 1 135 ? -22.349 2.856 21.961 1.00 17.60 ? 135 ILE A CG1 1 ATOM 1039 C CG2 . ILE A 1 135 ? -21.114 4.601 23.348 1.00 16.21 ? 135 ILE A CG2 1 ATOM 1040 C CD1 . ILE A 1 135 ? -21.664 3.268 20.644 1.00 17.72 ? 135 ILE A CD1 1 ATOM 1041 N N . ARG A 1 136 ? -22.164 4.176 26.373 1.00 17.21 ? 136 ARG A N 1 ATOM 1042 C CA . ARG A 1 136 ? -21.926 5.144 27.432 1.00 17.05 ? 136 ARG A CA 1 ATOM 1043 C C . ARG A 1 136 ? -20.492 5.611 27.495 1.00 16.48 ? 136 ARG A C 1 ATOM 1044 O O . ARG A 1 136 ? -19.594 4.916 27.015 1.00 16.70 ? 136 ARG A O 1 ATOM 1045 C CB . ARG A 1 136 ? -22.413 4.631 28.793 1.00 17.72 ? 136 ARG A CB 1 ATOM 1046 C CG . ARG A 1 136 ? -23.892 4.227 28.817 1.00 17.11 ? 136 ARG A CG 1 ATOM 1047 C CD . ARG A 1 136 ? -24.231 3.570 30.201 1.00 20.03 ? 136 ARG A CD 1 ATOM 1048 N NE . ARG A 1 136 ? -23.189 2.569 30.552 1.00 20.52 ? 136 ARG A NE 1 ATOM 1049 C CZ . ARG A 1 136 ? -23.102 1.992 31.750 1.00 18.11 ? 136 ARG A CZ 1 ATOM 1050 N NH1 . ARG A 1 136 ? -23.994 2.289 32.693 1.00 16.82 ? 136 ARG A NH1 1 ATOM 1051 N NH2 . ARG A 1 136 ? -22.168 1.094 31.974 1.00 15.37 ? 136 ARG A NH2 1 ATOM 1052 N N . SER A 1 137 ? -20.288 6.806 28.037 1.00 17.43 ? 137 SER A N 1 ATOM 1053 C CA . SER A 1 137 ? -18.937 7.394 28.180 1.00 19.31 ? 137 SER A CA 1 ATOM 1054 C C . SER A 1 137 ? -18.833 8.225 29.445 1.00 19.81 ? 137 SER A C 1 ATOM 1055 O O . SER A 1 137 ? -19.758 8.986 29.807 1.00 20.74 ? 137 SER A O 1 ATOM 1056 C CB . SER A 1 137 ? -18.525 8.291 26.977 1.00 19.95 ? 137 SER A CB 1 ATOM 1057 O OG . SER A 1 137 ? -17.255 8.955 27.179 1.00 19.91 ? 137 SER A OG 1 ATOM 1058 N N . SER A 1 138 ? -17.705 8.081 30.127 1.00 20.10 ? 138 SER A N 1 ATOM 1059 C CA . SER A 1 138 ? -17.423 8.886 31.298 1.00 22.01 ? 138 SER A CA 1 ATOM 1060 C C . SER A 1 138 ? -17.281 10.314 30.788 1.00 22.00 ? 138 SER A C 1 ATOM 1061 O O . SER A 1 138 ? -16.756 10.499 29.718 1.00 19.83 ? 138 SER A O 1 ATOM 1062 C CB . SER A 1 138 ? -16.126 8.431 32.000 1.00 22.00 ? 138 SER A CB 1 ATOM 1063 O OG . SER A 1 138 ? -16.069 8.953 33.322 1.00 23.32 ? 138 SER A OG 1 ATOM 1064 N N . GLY A 1 139 ? -17.703 11.308 31.559 1.00 22.86 ? 139 GLY A N 1 ATOM 1065 C CA . GLY A 1 139 ? -17.693 12.664 31.003 1.00 24.01 ? 139 GLY A CA 1 ATOM 1066 C C . GLY A 1 139 ? -16.359 13.346 31.175 1.00 25.88 ? 139 GLY A C 1 ATOM 1067 O O . GLY A 1 139 ? -16.138 14.088 32.181 1.00 28.58 ? 139 GLY A O 1 ATOM 1068 N N . SER A 1 140 ? -15.440 13.078 30.255 1.00 24.78 ? 140 SER A N 1 ATOM 1069 C CA . SER A 1 140 ? -14.149 13.759 30.186 1.00 23.52 ? 140 SER A CA 1 ATOM 1070 C C . SER A 1 140 ? -13.889 13.908 28.708 1.00 22.91 ? 140 SER A C 1 ATOM 1071 O O . SER A 1 140 ? -14.080 12.936 27.984 1.00 21.69 ? 140 SER A O 1 ATOM 1072 C CB . SER A 1 140 ? -13.068 12.868 30.785 1.00 24.29 ? 140 SER A CB 1 ATOM 1073 O OG . SER A 1 140 ? -11.778 13.173 30.259 1.00 23.76 ? 140 SER A OG 1 ATOM 1074 N N . SER A 1 141 ? -13.440 15.082 28.262 1.00 22.22 ? 141 SER A N 1 ATOM 1075 C CA . SER A 1 141 ? -13.368 15.381 26.839 1.00 23.01 ? 141 SER A CA 1 ATOM 1076 C C . SER A 1 141 ? -12.644 14.277 26.080 1.00 22.15 ? 141 SER A C 1 ATOM 1077 O O . SER A 1 141 ? -13.057 13.926 24.964 1.00 23.24 ? 141 SER A O 1 ATOM 1078 C CB . SER A 1 141 ? -12.592 16.679 26.537 1.00 23.07 ? 141 SER A CB 1 ATOM 1079 O OG . SER A 1 141 ? -13.063 17.732 27.332 1.00 31.08 ? 141 SER A OG 1 ATOM 1080 N N . ARG A 1 142 ? -11.536 13.781 26.619 1.00 20.18 ? 142 ARG A N 1 ATOM 1081 C CA . ARG A 1 142 ? -10.752 12.819 25.850 1.00 19.77 ? 142 ARG A CA 1 ATOM 1082 C C . ARG A 1 142 ? -11.472 11.449 25.743 1.00 19.12 ? 142 ARG A C 1 ATOM 1083 O O . ARG A 1 142 ? -11.307 10.690 24.773 1.00 19.15 ? 142 ARG A O 1 ATOM 1084 C CB . ARG A 1 142 ? -9.336 12.706 26.409 1.00 19.82 ? 142 ARG A CB 1 ATOM 1085 C CG . ARG A 1 142 ? -9.231 12.247 27.934 1.00 18.80 ? 142 ARG A CG 1 ATOM 1086 C CD . ARG A 1 142 ? -7.772 11.833 28.290 1.00 20.87 ? 142 ARG A CD 1 ATOM 1087 N NE . ARG A 1 142 ? -7.604 11.643 29.739 1.00 25.12 ? 142 ARG A NE 1 ATOM 1088 C CZ . ARG A 1 142 ? -7.391 12.656 30.604 1.00 25.16 ? 142 ARG A CZ 1 ATOM 1089 N NH1 . ARG A 1 142 ? -7.294 13.892 30.137 1.00 21.83 ? 142 ARG A NH1 1 ATOM 1090 N NH2 . ARG A 1 142 ? -7.256 12.422 31.913 1.00 20.52 ? 142 ARG A NH2 1 ATOM 1091 N N . VAL A 1 143 ? -12.332 11.172 26.714 1.00 19.33 ? 143 VAL A N 1 ATOM 1092 C CA . VAL A 1 143 ? -13.049 9.896 26.753 1.00 19.27 ? 143 VAL A CA 1 ATOM 1093 C C . VAL A 1 143 ? -14.225 9.948 25.748 1.00 19.88 ? 143 VAL A C 1 ATOM 1094 O O . VAL A 1 143 ? -14.364 9.053 24.903 1.00 19.37 ? 143 VAL A O 1 ATOM 1095 C CB . VAL A 1 143 ? -13.464 9.505 28.186 1.00 18.90 ? 143 VAL A CB 1 ATOM 1096 C CG1 . VAL A 1 143 ? -14.344 8.192 28.205 1.00 16.63 ? 143 VAL A CG1 1 ATOM 1097 C CG2 . VAL A 1 143 ? -12.232 9.299 29.015 1.00 18.98 ? 143 VAL A CG2 1 ATOM 1098 N N . ILE A 1 144 ? -15.011 11.019 25.847 1.00 19.51 ? 144 ILE A N 1 ATOM 1099 C CA . ILE A 1 144 ? -16.028 11.387 24.872 1.00 19.68 ? 144 ILE A CA 1 ATOM 1100 C C . ILE A 1 144 ? -15.485 11.454 23.414 1.00 19.87 ? 144 ILE A C 1 ATOM 1101 O O . ILE A 1 144 ? -16.082 10.857 22.499 1.00 20.19 ? 144 ILE A O 1 ATOM 1102 C CB . ILE A 1 144 ? -16.721 12.697 25.250 1.00 19.78 ? 144 ILE A CB 1 ATOM 1103 C CG1 . ILE A 1 144 ? -17.546 12.499 26.530 1.00 20.62 ? 144 ILE A CG1 1 ATOM 1104 C CG2 . ILE A 1 144 ? -17.666 13.188 24.117 1.00 19.94 ? 144 ILE A CG2 1 ATOM 1105 C CD1 . ILE A 1 144 ? -17.853 13.907 27.302 1.00 25.49 ? 144 ILE A CD1 1 ATOM 1106 N N . ALA A 1 145 ? -14.366 12.125 23.205 1.00 18.11 ? 145 ALA A N 1 ATOM 1107 C CA . ALA A 1 145 ? -13.863 12.203 21.861 1.00 17.92 ? 145 ALA A CA 1 ATOM 1108 C C . ALA A 1 145 ? -13.555 10.805 21.368 1.00 16.97 ? 145 ALA A C 1 ATOM 1109 O O . ALA A 1 145 ? -13.839 10.446 20.216 1.00 17.94 ? 145 ALA A O 1 ATOM 1110 C CB . ALA A 1 145 ? -12.636 13.124 21.759 1.00 16.84 ? 145 ALA A CB 1 ATOM 1111 N N . SER A 1 146 ? -12.960 10.011 22.251 1.00 17.69 ? 146 SER A N 1 ATOM 1112 C CA . SER A 1 146 ? -12.657 8.605 21.967 1.00 16.77 ? 146 SER A CA 1 ATOM 1113 C C . SER A 1 146 ? -13.915 7.804 21.615 1.00 16.94 ? 146 SER A C 1 ATOM 1114 O O . SER A 1 146 ? -13.936 7.114 20.597 1.00 17.05 ? 146 SER A O 1 ATOM 1115 C CB . SER A 1 146 ? -11.940 7.991 23.128 1.00 16.36 ? 146 SER A CB 1 ATOM 1116 O OG . SER A 1 146 ? -10.615 8.494 23.202 1.00 21.20 ? 146 SER A OG 1 ATOM 1117 N N . GLY A 1 147 ? -14.943 7.875 22.447 1.00 16.12 ? 147 GLY A N 1 ATOM 1118 C CA . GLY A 1 147 ? -16.205 7.259 22.084 1.00 17.63 ? 147 GLY A CA 1 ATOM 1119 C C . GLY A 1 147 ? -16.605 7.610 20.642 1.00 17.73 ? 147 GLY A C 1 ATOM 1120 O O . GLY A 1 147 ? -16.879 6.717 19.858 1.00 18.55 ? 147 GLY A O 1 ATOM 1121 N N . LYS A 1 148 ? -16.577 8.893 20.272 1.00 17.64 ? 148 LYS A N 1 ATOM 1122 C CA . LYS A 1 148 ? -16.972 9.311 18.916 1.00 17.33 ? 148 LYS A CA 1 ATOM 1123 C C . LYS A 1 148 ? -16.039 8.814 17.822 1.00 18.04 ? 148 LYS A C 1 ATOM 1124 O O . LYS A 1 148 ? -16.520 8.469 16.740 1.00 19.71 ? 148 LYS A O 1 ATOM 1125 C CB . LYS A 1 148 ? -17.195 10.844 18.853 1.00 18.00 ? 148 LYS A CB 1 ATOM 1126 C CG . LYS A 1 148 ? -18.401 11.303 19.745 1.00 16.29 ? 148 LYS A CG 1 ATOM 1127 C CD . LYS A 1 148 ? -18.389 12.812 19.959 1.00 22.89 ? 148 LYS A CD 1 ATOM 1128 C CE . LYS A 1 148 ? -19.591 13.260 20.761 1.00 23.39 ? 148 LYS A CE 1 ATOM 1129 N NZ . LYS A 1 148 ? -19.298 14.526 21.462 1.00 23.02 ? 148 LYS A NZ 1 ATOM 1130 N N . LYS A 1 149 ? -14.725 8.721 18.077 1.00 17.85 ? 149 LYS A N 1 ATOM 1131 C CA . LYS A 1 149 ? -13.846 8.166 17.069 1.00 18.09 ? 149 LYS A CA 1 ATOM 1132 C C . LYS A 1 149 ? -14.110 6.704 16.914 1.00 18.99 ? 149 LYS A C 1 ATOM 1133 O O . LYS A 1 149 ? -13.969 6.150 15.827 1.00 19.85 ? 149 LYS A O 1 ATOM 1134 C CB . LYS A 1 149 ? -12.357 8.371 17.417 1.00 18.55 ? 149 LYS A CB 1 ATOM 1135 C CG . LYS A 1 149 ? -11.927 9.842 17.252 1.00 18.63 ? 149 LYS A CG 1 ATOM 1136 C CD . LYS A 1 149 ? -11.609 10.126 15.751 1.00 16.49 ? 149 LYS A CD 1 ATOM 1137 C CE . LYS A 1 149 ? -11.603 11.613 15.458 1.00 17.41 ? 149 LYS A CE 1 ATOM 1138 N NZ . LYS A 1 149 ? -11.653 11.866 13.989 1.00 18.85 ? 149 LYS A NZ 1 ATOM 1139 N N . PHE A 1 150 ? -14.422 6.028 18.012 1.00 18.76 ? 150 PHE A N 1 ATOM 1140 C CA . PHE A 1 150 ? -14.736 4.620 17.908 1.00 18.81 ? 150 PHE A CA 1 ATOM 1141 C C . PHE A 1 150 ? -15.997 4.480 17.022 1.00 18.77 ? 150 PHE A C 1 ATOM 1142 O O . PHE A 1 150 ? -16.041 3.625 16.115 1.00 17.90 ? 150 PHE A O 1 ATOM 1143 C CB . PHE A 1 150 ? -14.917 4.030 19.325 1.00 17.78 ? 150 PHE A CB 1 ATOM 1144 C CG . PHE A 1 150 ? -15.359 2.593 19.368 1.00 16.44 ? 150 PHE A CG 1 ATOM 1145 C CD1 . PHE A 1 150 ? -16.661 2.230 19.086 1.00 16.10 ? 150 PHE A CD1 1 ATOM 1146 C CD2 . PHE A 1 150 ? -14.488 1.606 19.796 1.00 17.27 ? 150 PHE A CD2 1 ATOM 1147 C CE1 . PHE A 1 150 ? -17.055 0.864 19.184 1.00 15.02 ? 150 PHE A CE1 1 ATOM 1148 C CE2 . PHE A 1 150 ? -14.874 0.238 19.900 1.00 14.62 ? 150 PHE A CE2 1 ATOM 1149 C CZ . PHE A 1 150 ? -16.143 -0.116 19.638 1.00 14.09 ? 150 PHE A CZ 1 ATOM 1150 N N . ILE A 1 151 ? -17.011 5.316 17.293 1.00 19.08 ? 151 ILE A N 1 ATOM 1151 C CA . ILE A 1 151 ? -18.272 5.256 16.536 1.00 19.74 ? 151 ILE A CA 1 ATOM 1152 C C . ILE A 1 151 ? -18.018 5.598 15.069 1.00 21.39 ? 151 ILE A C 1 ATOM 1153 O O . ILE A 1 151 ? -18.513 4.911 14.173 1.00 20.91 ? 151 ILE A O 1 ATOM 1154 C CB . ILE A 1 151 ? -19.293 6.235 17.094 1.00 20.05 ? 151 ILE A CB 1 ATOM 1155 C CG1 . ILE A 1 151 ? -19.880 5.626 18.364 1.00 15.03 ? 151 ILE A CG1 1 ATOM 1156 C CG2 . ILE A 1 151 ? -20.322 6.565 16.021 1.00 18.17 ? 151 ILE A CG2 1 ATOM 1157 C CD1 . ILE A 1 151 ? -20.610 6.604 19.334 1.00 17.30 ? 151 ILE A CD1 1 ATOM 1158 N N . GLU A 1 152 ? -17.176 6.606 14.825 1.00 21.81 ? 152 GLU A N 1 ATOM 1159 C CA . GLU A 1 152 ? -16.704 6.878 13.446 1.00 22.54 ? 152 GLU A CA 1 ATOM 1160 C C . GLU A 1 152 ? -16.234 5.616 12.690 1.00 21.95 ? 152 GLU A C 1 ATOM 1161 O O . GLU A 1 152 ? -16.691 5.324 11.571 1.00 20.68 ? 152 GLU A O 1 ATOM 1162 C CB . GLU A 1 152 ? -15.565 7.865 13.455 1.00 22.47 ? 152 GLU A CB 1 ATOM 1163 C CG . GLU A 1 152 ? -15.694 8.987 12.430 1.00 27.02 ? 152 GLU A CG 1 ATOM 1164 C CD . GLU A 1 152 ? -14.494 9.974 12.394 1.00 29.46 ? 152 GLU A CD 1 ATOM 1165 O OE1 . GLU A 1 152 ? -14.163 10.635 13.424 1.00 31.79 ? 152 GLU A OE1 1 ATOM 1166 O OE2 . GLU A 1 152 ? -13.894 10.112 11.308 1.00 30.86 ? 152 GLU A OE2 1 ATOM 1167 N N . GLY A 1 153 ? -15.321 4.868 13.281 1.00 20.87 ? 153 GLY A N 1 ATOM 1168 C CA . GLY A 1 153 ? -14.728 3.752 12.553 1.00 20.30 ? 153 GLY A CA 1 ATOM 1169 C C . GLY A 1 153 ? -15.713 2.603 12.370 1.00 20.56 ? 153 GLY A C 1 ATOM 1170 O O . GLY A 1 153 ? -15.700 1.913 11.337 1.00 21.41 ? 153 GLY A O 1 ATOM 1171 N N . PHE A 1 154 ? -16.552 2.389 13.383 1.00 20.33 ? 154 PHE A N 1 ATOM 1172 C CA . PHE A 1 154 ? -17.634 1.422 13.351 1.00 20.98 ? 154 PHE A CA 1 ATOM 1173 C C . PHE A 1 154 ? -18.573 1.742 12.187 1.00 21.90 ? 154 PHE A C 1 ATOM 1174 O O . PHE A 1 154 ? -18.942 0.867 11.433 1.00 21.52 ? 154 PHE A O 1 ATOM 1175 C CB . PHE A 1 154 ? -18.404 1.504 14.689 1.00 19.63 ? 154 PHE A CB 1 ATOM 1176 C CG . PHE A 1 154 ? -19.518 0.499 14.879 1.00 20.32 ? 154 PHE A CG 1 ATOM 1177 C CD1 . PHE A 1 154 ? -20.817 0.796 14.453 1.00 20.76 ? 154 PHE A CD1 1 ATOM 1178 C CD2 . PHE A 1 154 ? -19.305 -0.688 15.602 1.00 18.98 ? 154 PHE A CD2 1 ATOM 1179 C CE1 . PHE A 1 154 ? -21.872 -0.091 14.665 1.00 20.01 ? 154 PHE A CE1 1 ATOM 1180 C CE2 . PHE A 1 154 ? -20.363 -1.569 15.863 1.00 16.87 ? 154 PHE A CE2 1 ATOM 1181 C CZ . PHE A 1 154 ? -21.644 -1.301 15.388 1.00 19.16 ? 154 PHE A CZ 1 ATOM 1182 N N . GLN A 1 155 ? -18.997 2.998 12.080 1.00 23.33 ? 155 GLN A N 1 ATOM 1183 C CA . GLN A 1 155 ? -20.019 3.404 11.099 1.00 24.34 ? 155 GLN A CA 1 ATOM 1184 C C . GLN A 1 155 ? -19.410 3.361 9.689 1.00 24.20 ? 155 GLN A C 1 ATOM 1185 O O . GLN A 1 155 ? -20.061 2.886 8.772 1.00 24.07 ? 155 GLN A O 1 ATOM 1186 C CB . GLN A 1 155 ? -20.665 4.758 11.491 1.00 24.20 ? 155 GLN A CB 1 ATOM 1187 C CG . GLN A 1 155 ? -21.798 5.283 10.538 1.00 34.33 ? 155 GLN A CG 1 ATOM 1188 C CD . GLN A 1 155 ? -22.944 4.246 10.153 1.00 41.05 ? 155 GLN A CD 1 ATOM 1189 O OE1 . GLN A 1 155 ? -23.838 3.936 10.976 1.00 43.60 ? 155 GLN A OE1 1 ATOM 1190 N NE2 . GLN A 1 155 ? -22.927 3.762 8.874 1.00 40.32 ? 155 GLN A NE2 1 ATOM 1191 N N . SER A 1 156 ? -18.140 3.751 9.530 1.00 23.97 ? 156 SER A N 1 ATOM 1192 C CA . SER A 1 156 ? -17.451 3.558 8.257 1.00 24.33 ? 156 SER A CA 1 ATOM 1193 C C . SER A 1 156 ? -17.502 2.124 7.758 1.00 24.14 ? 156 SER A C 1 ATOM 1194 O O . SER A 1 156 ? -17.743 1.894 6.579 1.00 26.01 ? 156 SER A O 1 ATOM 1195 C CB . SER A 1 156 ? -15.981 3.978 8.334 1.00 25.06 ? 156 SER A CB 1 ATOM 1196 O OG . SER A 1 156 ? -15.849 5.369 8.075 1.00 28.24 ? 156 SER A OG 1 ATOM 1197 N N . THR A 1 157 ? -17.274 1.162 8.644 1.00 22.79 ? 157 THR A N 1 ATOM 1198 C CA . THR A 1 157 ? -17.229 -0.240 8.293 1.00 21.64 ? 157 THR A CA 1 ATOM 1199 C C . THR A 1 157 ? -18.624 -0.782 8.045 1.00 21.82 ? 157 THR A C 1 ATOM 1200 O O . THR A 1 157 ? -18.822 -1.537 7.135 1.00 21.55 ? 157 THR A O 1 ATOM 1201 C CB . THR A 1 157 ? -16.577 -1.057 9.409 1.00 21.06 ? 157 THR A CB 1 ATOM 1202 O OG1 . THR A 1 157 ? -15.461 -0.335 9.919 1.00 21.01 ? 157 THR A OG1 1 ATOM 1203 C CG2 . THR A 1 157 ? -16.067 -2.368 8.891 1.00 20.95 ? 157 THR A CG2 1 ATOM 1204 N N . LYS A 1 158 ? -19.606 -0.420 8.867 1.00 22.03 ? 158 LYS A N 1 ATOM 1205 C CA . LYS A 1 158 ? -20.976 -0.831 8.576 1.00 21.86 ? 158 LYS A CA 1 ATOM 1206 C C . LYS A 1 158 ? -21.381 -0.434 7.113 1.00 23.75 ? 158 LYS A C 1 ATOM 1207 O O . LYS A 1 158 ? -21.870 -1.291 6.359 1.00 24.55 ? 158 LYS A O 1 ATOM 1208 C CB . LYS A 1 158 ? -21.956 -0.282 9.611 1.00 21.47 ? 158 LYS A CB 1 ATOM 1209 C CG . LYS A 1 158 ? -23.320 -1.035 9.678 1.00 17.73 ? 158 LYS A CG 1 ATOM 1210 C CD . LYS A 1 158 ? -24.292 -0.328 10.608 1.00 14.25 ? 158 LYS A CD 1 ATOM 1211 C CE . LYS A 1 158 ? -25.507 -1.226 10.785 1.00 13.86 ? 158 LYS A CE 1 ATOM 1212 N NZ . LYS A 1 158 ? -26.517 -0.589 11.682 1.00 16.99 ? 158 LYS A NZ 1 ATOM 1213 N N . LEU A 1 159 ? -21.146 0.831 6.721 1.00 24.59 ? 159 LEU A N 1 ATOM 1214 C CA . LEU A 1 159 ? -21.421 1.316 5.379 1.00 26.23 ? 159 LEU A CA 1 ATOM 1215 C C . LEU A 1 159 ? -20.796 0.482 4.244 1.00 26.92 ? 159 LEU A C 1 ATOM 1216 O O . LEU A 1 159 ? -21.351 0.416 3.141 1.00 26.24 ? 159 LEU A O 1 ATOM 1217 C CB . LEU A 1 159 ? -20.914 2.730 5.201 1.00 27.68 ? 159 LEU A CB 1 ATOM 1218 C CG . LEU A 1 159 ? -21.736 3.985 5.521 1.00 31.26 ? 159 LEU A CG 1 ATOM 1219 C CD1 . LEU A 1 159 ? -20.886 5.232 5.182 1.00 32.28 ? 159 LEU A CD1 1 ATOM 1220 C CD2 . LEU A 1 159 ? -23.126 3.973 4.799 1.00 31.14 ? 159 LEU A CD2 1 ATOM 1221 N N . LYS A 1 160 ? -19.658 -0.152 4.501 1.00 27.09 ? 160 LYS A N 1 ATOM 1222 C CA . LYS A 1 160 ? -18.993 -0.932 3.468 1.00 28.66 ? 160 LYS A CA 1 ATOM 1223 C C . LYS A 1 160 ? -19.347 -2.392 3.514 1.00 28.09 ? 160 LYS A C 1 ATOM 1224 O O . LYS A 1 160 ? -18.782 -3.182 2.767 1.00 29.95 ? 160 LYS A O 1 ATOM 1225 C CB . LYS A 1 160 ? -17.460 -0.743 3.515 1.00 28.77 ? 160 LYS A CB 1 ATOM 1226 C CG . LYS A 1 160 ? -17.100 0.682 3.159 1.00 33.96 ? 160 LYS A CG 1 ATOM 1227 C CD . LYS A 1 160 ? -15.637 0.870 2.730 1.00 43.03 ? 160 LYS A CD 1 ATOM 1228 C CE . LYS A 1 160 ? -14.772 1.450 3.877 1.00 45.91 ? 160 LYS A CE 1 ATOM 1229 N NZ . LYS A 1 160 ? -14.501 0.394 4.906 1.00 43.00 ? 160 LYS A NZ 1 ATOM 1230 N N . ASP A 1 161 ? -20.295 -2.757 4.356 1.00 27.57 ? 161 ASP A N 1 ATOM 1231 C CA . ASP A 1 161 ? -20.538 -4.149 4.612 1.00 27.49 ? 161 ASP A CA 1 ATOM 1232 C C . ASP A 1 161 ? -21.808 -4.511 3.851 1.00 27.45 ? 161 ASP A C 1 ATOM 1233 O O . ASP A 1 161 ? -22.864 -3.950 4.140 1.00 27.06 ? 161 ASP A O 1 ATOM 1234 C CB . ASP A 1 161 ? -20.720 -4.368 6.116 1.00 27.30 ? 161 ASP A CB 1 ATOM 1235 C CG . ASP A 1 161 ? -21.136 -5.775 6.463 1.00 26.27 ? 161 ASP A CG 1 ATOM 1236 O OD1 . ASP A 1 161 ? -21.075 -6.692 5.614 1.00 29.15 ? 161 ASP A OD1 1 ATOM 1237 O OD2 . ASP A 1 161 ? -21.517 -5.979 7.618 1.00 25.08 ? 161 ASP A OD2 1 ATOM 1238 N N . PRO A 1 162 ? -21.695 -5.468 2.895 1.00 27.46 ? 162 PRO A N 1 ATOM 1239 C CA . PRO A 1 162 ? -22.803 -5.848 2.017 1.00 27.27 ? 162 PRO A CA 1 ATOM 1240 C C . PRO A 1 162 ? -23.941 -6.465 2.801 1.00 27.39 ? 162 PRO A C 1 ATOM 1241 O O . PRO A 1 162 ? -25.074 -6.463 2.350 1.00 26.60 ? 162 PRO A O 1 ATOM 1242 C CB . PRO A 1 162 ? -22.154 -6.879 1.071 1.00 27.63 ? 162 PRO A CB 1 ATOM 1243 C CG . PRO A 1 162 ? -20.922 -7.379 1.812 1.00 26.88 ? 162 PRO A CG 1 ATOM 1244 C CD . PRO A 1 162 ? -20.447 -6.221 2.575 1.00 26.89 ? 162 PRO A CD 1 ATOM 1245 N N . ARG A 1 163 ? -23.630 -6.947 4.002 1.00 28.13 ? 163 ARG A N 1 ATOM 1246 C CA . ARG A 1 163 ? -24.635 -7.596 4.863 1.00 28.69 ? 163 ARG A CA 1 ATOM 1247 C C . ARG A 1 163 ? -25.333 -6.684 5.845 1.00 28.64 ? 163 ARG A C 1 ATOM 1248 O O . ARG A 1 163 ? -26.326 -7.064 6.443 1.00 28.92 ? 163 ARG A O 1 ATOM 1249 C CB . ARG A 1 163 ? -24.051 -8.844 5.531 1.00 28.34 ? 163 ARG A CB 1 ATOM 1250 C CG . ARG A 1 163 ? -23.562 -9.798 4.462 1.00 28.62 ? 163 ARG A CG 1 ATOM 1251 C CD . ARG A 1 163 ? -22.705 -10.964 4.955 1.00 28.61 ? 163 ARG A CD 1 ATOM 1252 N NE . ARG A 1 163 ? -21.441 -10.880 4.238 1.00 35.16 ? 163 ARG A NE 1 ATOM 1253 C CZ . ARG A 1 163 ? -21.087 -11.587 3.181 1.00 33.14 ? 163 ARG A CZ 1 ATOM 1254 N NH1 . ARG A 1 163 ? -21.863 -12.511 2.700 1.00 36.38 ? 163 ARG A NH1 1 ATOM 1255 N NH2 . ARG A 1 163 ? -19.917 -11.384 2.649 1.00 34.62 ? 163 ARG A NH2 1 ATOM 1256 N N . ALA A 1 164 ? -24.847 -5.460 5.975 1.00 29.38 ? 164 ALA A N 1 ATOM 1257 C CA . ALA A 1 164 ? -25.417 -4.516 6.926 1.00 30.47 ? 164 ALA A CA 1 ATOM 1258 C C . ALA A 1 164 ? -26.818 -4.060 6.533 1.00 31.76 ? 164 ALA A C 1 ATOM 1259 O O . ALA A 1 164 ? -27.032 -3.677 5.390 1.00 34.24 ? 164 ALA A O 1 ATOM 1260 C CB . ALA A 1 164 ? -24.519 -3.330 7.031 1.00 30.38 ? 164 ALA A CB 1 ATOM 1261 N N . GLN A 1 165 ? -27.775 -4.099 7.462 1.00 32.09 ? 165 GLN A N 1 ATOM 1262 C CA . GLN A 1 165 ? -29.049 -3.482 7.252 1.00 32.19 ? 165 GLN A CA 1 ATOM 1263 C C . GLN A 1 165 ? -28.912 -1.953 7.306 1.00 33.40 ? 165 GLN A C 1 ATOM 1264 O O . GLN A 1 165 ? -28.708 -1.402 8.381 1.00 33.91 ? 165 GLN A O 1 ATOM 1265 C CB . GLN A 1 165 ? -30.011 -3.967 8.292 1.00 32.37 ? 165 GLN A CB 1 ATOM 1266 C CG . GLN A 1 165 ? -31.347 -3.227 8.277 1.00 33.16 ? 165 GLN A CG 1 ATOM 1267 C CD . GLN A 1 165 ? -32.329 -3.963 9.090 1.00 34.68 ? 165 GLN A CD 1 ATOM 1268 O OE1 . GLN A 1 165 ? -32.025 -5.054 9.562 1.00 36.93 ? 165 GLN A OE1 1 ATOM 1269 N NE2 . GLN A 1 165 ? -33.520 -3.393 9.286 1.00 36.69 ? 165 GLN A NE2 1 ATOM 1270 N N . PRO A 1 166 ? -28.987 -1.263 6.133 1.00 33.78 ? 166 PRO A N 1 ATOM 1271 C CA . PRO A 1 166 ? -28.772 0.190 5.983 1.00 33.28 ? 166 PRO A CA 1 ATOM 1272 C C . PRO A 1 166 ? -29.893 1.086 6.519 1.00 33.52 ? 166 PRO A C 1 ATOM 1273 O O . PRO A 1 166 ? -30.992 0.597 6.876 1.00 32.14 ? 166 PRO A O 1 ATOM 1274 C CB . PRO A 1 166 ? -28.694 0.379 4.470 1.00 34.17 ? 166 PRO A CB 1 ATOM 1275 C CG . PRO A 1 166 ? -29.627 -0.744 3.941 1.00 34.78 ? 166 PRO A CG 1 ATOM 1276 C CD . PRO A 1 166 ? -29.313 -1.910 4.843 1.00 33.70 ? 166 PRO A CD 1 ATOM 1277 N N . GLY A 1 167 ? -29.589 2.395 6.579 1.00 33.81 ? 167 GLY A N 1 ATOM 1278 C CA . GLY A 1 167 ? -30.487 3.416 7.152 1.00 33.88 ? 167 GLY A CA 1 ATOM 1279 C C . GLY A 1 167 ? -31.092 3.082 8.519 1.00 33.96 ? 167 GLY A C 1 ATOM 1280 O O . GLY A 1 167 ? -32.295 3.304 8.764 1.00 34.22 ? 167 GLY A O 1 ATOM 1281 N N . GLN A 1 168 ? -30.270 2.518 9.409 1.00 32.97 ? 168 GLN A N 1 ATOM 1282 C CA . GLN A 1 168 ? -30.677 2.310 10.813 1.00 31.26 ? 168 GLN A CA 1 ATOM 1283 C C . GLN A 1 168 ? -30.279 3.596 11.555 1.00 29.79 ? 168 GLN A C 1 ATOM 1284 O O . GLN A 1 168 ? -29.541 4.388 11.008 1.00 28.26 ? 168 GLN A O 1 ATOM 1285 C CB . GLN A 1 168 ? -29.960 1.099 11.356 1.00 31.08 ? 168 GLN A CB 1 ATOM 1286 C CG . GLN A 1 168 ? -30.482 -0.181 10.771 1.00 31.41 ? 168 GLN A CG 1 ATOM 1287 C CD . GLN A 1 168 ? -30.139 -1.332 11.660 1.00 31.54 ? 168 GLN A CD 1 ATOM 1288 O OE1 . GLN A 1 168 ? -28.994 -1.781 11.672 1.00 27.93 ? 168 GLN A OE1 1 ATOM 1289 N NE2 . GLN A 1 168 ? -31.115 -1.792 12.450 1.00 29.58 ? 168 GLN A NE2 1 ATOM 1290 N N . SER A 1 169 ? -30.759 3.847 12.768 1.00 29.85 ? 169 SER A N 1 ATOM 1291 C CA . SER A 1 169 ? -30.229 5.071 13.449 1.00 29.47 ? 169 SER A CA 1 ATOM 1292 C C . SER A 1 169 ? -28.701 4.949 13.631 1.00 28.32 ? 169 SER A C 1 ATOM 1293 O O . SER A 1 169 ? -28.144 3.869 13.622 1.00 26.92 ? 169 SER A O 1 ATOM 1294 C CB . SER A 1 169 ? -30.960 5.413 14.744 1.00 28.88 ? 169 SER A CB 1 ATOM 1295 O OG . SER A 1 169 ? -31.216 4.229 15.459 1.00 33.51 ? 169 SER A OG 1 ATOM 1296 N N . SER A 1 170 ? -28.009 6.072 13.701 1.00 28.37 ? 170 SER A N 1 ATOM 1297 C CA . SER A 1 170 ? -26.570 6.018 13.952 1.00 28.63 ? 170 SER A CA 1 ATOM 1298 C C . SER A 1 170 ? -26.295 5.503 15.370 1.00 26.94 ? 170 SER A C 1 ATOM 1299 O O . SER A 1 170 ? -27.100 5.749 16.291 1.00 25.89 ? 170 SER A O 1 ATOM 1300 C CB . SER A 1 170 ? -25.937 7.415 13.833 1.00 30.05 ? 170 SER A CB 1 ATOM 1301 O OG . SER A 1 170 ? -26.243 8.054 12.582 1.00 35.40 ? 170 SER A OG 1 ATOM 1302 N N . PRO A 1 171 ? -25.148 4.824 15.559 1.00 25.92 ? 171 PRO A N 1 ATOM 1303 C CA . PRO A 1 171 ? -24.640 4.658 16.931 1.00 25.14 ? 171 PRO A CA 1 ATOM 1304 C C . PRO A 1 171 ? -24.200 6.008 17.453 1.00 24.70 ? 171 PRO A C 1 ATOM 1305 O O . PRO A 1 171 ? -23.564 6.752 16.695 1.00 25.64 ? 171 PRO A O 1 ATOM 1306 C CB . PRO A 1 171 ? -23.417 3.777 16.775 1.00 25.00 ? 171 PRO A CB 1 ATOM 1307 C CG . PRO A 1 171 ? -23.232 3.543 15.334 1.00 25.80 ? 171 PRO A CG 1 ATOM 1308 C CD . PRO A 1 171 ? -24.236 4.289 14.540 1.00 25.59 ? 171 PRO A CD 1 ATOM 1309 N N . LYS A 1 172 ? -24.512 6.322 18.717 1.00 22.78 ? 172 LYS A N 1 ATOM 1310 C CA . LYS A 1 172 ? -24.074 7.579 19.330 1.00 22.61 ? 172 LYS A CA 1 ATOM 1311 C C . LYS A 1 172 ? -23.802 7.302 20.805 1.00 22.50 ? 172 LYS A C 1 ATOM 1312 O O . LYS A 1 172 ? -24.178 6.240 21.338 1.00 22.64 ? 172 LYS A O 1 ATOM 1313 C CB . LYS A 1 172 ? -25.173 8.637 19.222 1.00 21.98 ? 172 LYS A CB 1 ATOM 1314 C CG . LYS A 1 172 ? -26.448 8.106 19.844 1.00 23.11 ? 172 LYS A CG 1 ATOM 1315 C CD . LYS A 1 172 ? -27.667 9.011 19.707 1.00 23.57 ? 172 LYS A CD 1 ATOM 1316 C CE . LYS A 1 172 ? -28.900 8.148 20.049 1.00 26.17 ? 172 LYS A CE 1 ATOM 1317 N NZ . LYS A 1 172 ? -29.876 9.012 20.742 1.00 28.87 ? 172 LYS A NZ 1 ATOM 1318 N N . ILE A 1 173 ? -23.176 8.277 21.462 1.00 21.80 ? 173 ILE A N 1 ATOM 1319 C CA . ILE A 1 173 ? -23.013 8.222 22.879 1.00 20.92 ? 173 ILE A CA 1 ATOM 1320 C C . ILE A 1 173 ? -24.364 8.516 23.515 1.00 22.19 ? 173 ILE A C 1 ATOM 1321 O O . ILE A 1 173 ? -24.817 9.679 23.527 1.00 23.43 ? 173 ILE A O 1 ATOM 1322 C CB . ILE A 1 173 ? -21.912 9.174 23.362 1.00 20.43 ? 173 ILE A CB 1 ATOM 1323 C CG1 . ILE A 1 173 ? -20.574 8.787 22.725 1.00 17.81 ? 173 ILE A CG1 1 ATOM 1324 C CG2 . ILE A 1 173 ? -21.759 9.106 24.851 1.00 18.73 ? 173 ILE A CG2 1 ATOM 1325 C CD1 . ILE A 1 173 ? -19.475 9.849 23.101 1.00 21.76 ? 173 ILE A CD1 1 ATOM 1326 N N . ASP A 1 174 ? -25.010 7.459 24.005 1.00 21.81 ? 174 ASP A N 1 ATOM 1327 C CA . ASP A 1 174 ? -26.333 7.587 24.588 1.00 23.37 ? 174 ASP A CA 1 ATOM 1328 C C . ASP A 1 174 ? -26.387 8.279 25.919 1.00 24.22 ? 174 ASP A C 1 ATOM 1329 O O . ASP A 1 174 ? -27.404 8.903 26.262 1.00 25.75 ? 174 ASP A O 1 ATOM 1330 C CB . ASP A 1 174 ? -27.016 6.197 24.693 1.00 23.17 ? 174 ASP A CB 1 ATOM 1331 C CG . ASP A 1 174 ? -27.185 5.539 23.291 1.00 24.98 ? 174 ASP A CG 1 ATOM 1332 O OD1 . ASP A 1 174 ? -28.156 5.888 22.574 1.00 27.22 ? 174 ASP A OD1 1 ATOM 1333 O OD2 . ASP A 1 174 ? -26.313 4.745 22.880 1.00 21.86 ? 174 ASP A OD2 1 ATOM 1334 N N . VAL A 1 175 ? -25.348 8.070 26.727 1.00 25.39 ? 175 VAL A N 1 ATOM 1335 C CA . VAL A 1 175 ? -25.269 8.594 28.091 1.00 24.72 ? 175 VAL A CA 1 ATOM 1336 C C . VAL A 1 175 ? -23.836 9.064 28.323 1.00 24.55 ? 175 VAL A C 1 ATOM 1337 O O . VAL A 1 175 ? -22.892 8.289 28.178 1.00 24.12 ? 175 VAL A O 1 ATOM 1338 C CB . VAL A 1 175 ? -25.599 7.495 29.162 1.00 24.96 ? 175 VAL A CB 1 ATOM 1339 C CG1 . VAL A 1 175 ? -25.649 8.115 30.510 1.00 24.45 ? 175 VAL A CG1 1 ATOM 1340 C CG2 . VAL A 1 175 ? -26.924 6.745 28.874 1.00 25.56 ? 175 VAL A CG2 1 ATOM 1341 N N . VAL A 1 176 ? -23.689 10.329 28.689 1.00 24.99 ? 176 VAL A N 1 ATOM 1342 C CA . VAL A 1 176 ? -22.428 10.870 29.206 1.00 25.12 ? 176 VAL A CA 1 ATOM 1343 C C . VAL A 1 176 ? -22.575 10.892 30.708 1.00 24.61 ? 176 VAL A C 1 ATOM 1344 O O . VAL A 1 176 ? -23.452 11.575 31.216 1.00 24.79 ? 176 VAL A O 1 ATOM 1345 C CB . VAL A 1 176 ? -22.170 12.298 28.711 1.00 26.11 ? 176 VAL A CB 1 ATOM 1346 C CG1 . VAL A 1 176 ? -20.852 12.841 29.309 1.00 28.36 ? 176 VAL A CG1 1 ATOM 1347 C CG2 . VAL A 1 176 ? -22.132 12.326 27.181 1.00 25.16 ? 176 VAL A CG2 1 ATOM 1348 N N . ILE A 1 177 ? -21.768 10.082 31.402 1.00 22.87 ? 177 ILE A N 1 ATOM 1349 C CA . ILE A 1 177 ? -21.804 10.005 32.857 1.00 21.52 ? 177 ILE A CA 1 ATOM 1350 C C . ILE A 1 177 ? -20.873 11.062 33.458 1.00 21.64 ? 177 ILE A C 1 ATOM 1351 O O . ILE A 1 177 ? -19.664 11.113 33.151 1.00 20.96 ? 177 ILE A O 1 ATOM 1352 C CB . ILE A 1 177 ? -21.372 8.596 33.403 1.00 20.28 ? 177 ILE A CB 1 ATOM 1353 C CG1 . ILE A 1 177 ? -22.185 7.471 32.727 1.00 17.91 ? 177 ILE A CG1 1 ATOM 1354 C CG2 . ILE A 1 177 ? -21.600 8.584 34.828 1.00 22.18 ? 177 ILE A CG2 1 ATOM 1355 C CD1 . ILE A 1 177 ? -21.955 6.108 33.232 1.00 16.45 ? 177 ILE A CD1 1 ATOM 1356 N N . SER A 1 178 ? -21.439 11.902 34.315 1.00 22.55 ? 178 SER A N 1 ATOM 1357 C CA . SER A 1 178 ? -20.680 12.946 35.001 1.00 23.37 ? 178 SER A CA 1 ATOM 1358 C C . SER A 1 178 ? -19.523 12.478 35.886 1.00 24.01 ? 178 SER A C 1 ATOM 1359 O O . SER A 1 178 ? -19.714 11.590 36.766 1.00 22.73 ? 178 SER A O 1 ATOM 1360 C CB . SER A 1 178 ? -21.611 13.793 35.858 1.00 22.77 ? 178 SER A CB 1 ATOM 1361 O OG . SER A 1 178 ? -20.839 14.848 36.430 1.00 23.99 ? 178 SER A OG 1 ATOM 1362 N N . GLU A 1 179 ? -18.355 13.106 35.694 1.00 24.29 ? 179 GLU A N 1 ATOM 1363 C CA . GLU A 1 179 ? -17.229 12.930 36.632 1.00 26.23 ? 179 GLU A CA 1 ATOM 1364 C C . GLU A 1 179 ? -17.244 13.922 37.818 1.00 27.29 ? 179 GLU A C 1 ATOM 1365 O O . GLU A 1 179 ? -16.323 13.920 38.632 1.00 27.76 ? 179 GLU A O 1 ATOM 1366 C CB . GLU A 1 179 ? -15.859 13.034 35.934 1.00 25.96 ? 179 GLU A CB 1 ATOM 1367 C CG . GLU A 1 179 ? -15.738 12.100 34.770 1.00 27.81 ? 179 GLU A CG 1 ATOM 1368 C CD . GLU A 1 179 ? -14.362 12.074 34.144 1.00 29.58 ? 179 GLU A CD 1 ATOM 1369 O OE1 . GLU A 1 179 ? -13.480 12.850 34.556 1.00 31.76 ? 179 GLU A OE1 1 ATOM 1370 O OE2 . GLU A 1 179 ? -14.162 11.265 33.224 1.00 32.55 ? 179 GLU A OE2 1 ATOM 1371 N N . ALA A 1 180 ? -18.251 14.790 37.932 1.00 28.34 ? 180 ALA A N 1 ATOM 1372 C CA . ALA A 1 180 ? -18.310 15.668 39.125 1.00 28.39 ? 180 ALA A CA 1 ATOM 1373 C C . ALA A 1 180 ? -18.190 14.800 40.391 1.00 29.22 ? 180 ALA A C 1 ATOM 1374 O O . ALA A 1 180 ? -18.462 13.567 40.367 1.00 27.98 ? 180 ALA A O 1 ATOM 1375 C CB . ALA A 1 180 ? -19.550 16.506 39.171 1.00 27.20 ? 180 ALA A CB 1 ATOM 1376 N N . SER A 1 181 ? -17.771 15.459 41.475 1.00 29.47 ? 181 SER A N 1 ATOM 1377 C CA . SER A 1 181 ? -17.441 14.811 42.750 1.00 30.42 ? 181 SER A CA 1 ATOM 1378 C C . SER A 1 181 ? -18.659 14.191 43.427 1.00 29.86 ? 181 SER A C 1 ATOM 1379 O O . SER A 1 181 ? -18.524 13.221 44.202 1.00 30.59 ? 181 SER A O 1 ATOM 1380 C CB . SER A 1 181 ? -16.763 15.832 43.691 1.00 31.36 ? 181 SER A CB 1 ATOM 1381 O OG . SER A 1 181 ? -17.542 17.043 43.758 1.00 32.08 ? 181 SER A OG 1 ATOM 1382 N N . SER A 1 182 ? -19.843 14.725 43.118 1.00 29.50 ? 182 SER A N 1 ATOM 1383 C CA . SER A 1 182 ? -21.104 14.171 43.637 1.00 29.27 ? 182 SER A CA 1 ATOM 1384 C C . SER A 1 182 ? -21.681 13.065 42.748 1.00 28.29 ? 182 SER A C 1 ATOM 1385 O O . SER A 1 182 ? -22.666 12.414 43.114 1.00 29.08 ? 182 SER A O 1 ATOM 1386 C CB . SER A 1 182 ? -22.162 15.267 43.690 1.00 30.45 ? 182 SER A CB 1 ATOM 1387 O OG . SER A 1 182 ? -22.137 16.042 42.483 1.00 32.40 ? 182 SER A OG 1 ATOM 1388 N N . SER A 1 183 ? -21.133 12.901 41.555 1.00 26.66 ? 183 SER A N 1 ATOM 1389 C CA . SER A 1 183 ? -21.717 11.939 40.602 1.00 25.51 ? 183 SER A CA 1 ATOM 1390 C C . SER A 1 183 ? -21.426 10.430 40.900 1.00 23.75 ? 183 SER A C 1 ATOM 1391 O O . SER A 1 183 ? -20.271 10.033 41.061 1.00 21.93 ? 183 SER A O 1 ATOM 1392 C CB . SER A 1 183 ? -21.244 12.295 39.216 1.00 25.35 ? 183 SER A CB 1 ATOM 1393 O OG . SER A 1 183 ? -21.832 11.424 38.287 1.00 27.68 ? 183 SER A OG 1 ATOM 1394 N N . ASN A 1 184 ? -22.478 9.619 41.009 1.00 22.06 ? 184 ASN A N 1 ATOM 1395 C CA . ASN A 1 184 ? -22.310 8.169 40.935 1.00 21.59 ? 184 ASN A CA 1 ATOM 1396 C C . ASN A 1 184 ? -21.937 7.762 39.515 1.00 20.76 ? 184 ASN A C 1 ATOM 1397 O O . ASN A 1 184 ? -22.793 7.785 38.653 1.00 20.49 ? 184 ASN A O 1 ATOM 1398 C CB . ASN A 1 184 ? -23.577 7.423 41.405 1.00 22.27 ? 184 ASN A CB 1 ATOM 1399 C CG . ASN A 1 184 ? -23.863 7.630 42.884 1.00 24.16 ? 184 ASN A CG 1 ATOM 1400 O OD1 . ASN A 1 184 ? -23.083 8.250 43.592 1.00 26.19 ? 184 ASN A OD1 1 ATOM 1401 N ND2 . ASN A 1 184 ? -24.988 7.117 43.349 1.00 28.52 ? 184 ASN A ND2 1 ATOM 1402 N N . ASN A 1 185 ? -20.665 7.423 39.290 1.00 19.36 ? 185 ASN A N 1 ATOM 1403 C CA . ASN A 1 185 ? -20.102 7.030 38.003 1.00 18.20 ? 185 ASN A CA 1 ATOM 1404 C C . ASN A 1 185 ? -19.492 5.598 38.083 1.00 18.75 ? 185 ASN A C 1 ATOM 1405 O O . ASN A 1 185 ? -18.435 5.423 38.693 1.00 19.28 ? 185 ASN A O 1 ATOM 1406 C CB . ASN A 1 185 ? -19.027 8.048 37.670 1.00 17.30 ? 185 ASN A CB 1 ATOM 1407 C CG . ASN A 1 185 ? -18.463 7.908 36.258 1.00 18.84 ? 185 ASN A CG 1 ATOM 1408 O OD1 . ASN A 1 185 ? -17.842 8.837 35.702 1.00 21.12 ? 185 ASN A OD1 1 ATOM 1409 N ND2 . ASN A 1 185 ? -18.652 6.765 35.678 1.00 14.20 ? 185 ASN A ND2 1 ATOM 1410 N N . THR A 1 186 ? -20.129 4.587 37.480 1.00 18.11 ? 186 THR A N 1 ATOM 1411 C CA . THR A 1 186 ? -19.624 3.218 37.519 1.00 17.56 ? 186 THR A CA 1 ATOM 1412 C C . THR A 1 186 ? -18.315 3.022 36.765 1.00 19.16 ? 186 THR A C 1 ATOM 1413 O O . THR A 1 186 ? -17.533 2.054 37.034 1.00 18.33 ? 186 THR A O 1 ATOM 1414 C CB . THR A 1 186 ? -20.654 2.188 37.041 1.00 17.69 ? 186 THR A CB 1 ATOM 1415 O OG1 . THR A 1 186 ? -21.012 2.460 35.668 1.00 16.38 ? 186 THR A OG1 1 ATOM 1416 C CG2 . THR A 1 186 ? -21.910 2.195 37.966 1.00 13.59 ? 186 THR A CG2 1 ATOM 1417 N N . LEU A 1 187 ? -18.040 3.971 35.886 1.00 18.98 ? 187 LEU A N 1 ATOM 1418 C CA . LEU A 1 187 ? -16.953 3.842 34.937 1.00 20.21 ? 187 LEU A CA 1 ATOM 1419 C C . LEU A 1 187 ? -15.677 4.317 35.570 1.00 21.62 ? 187 LEU A C 1 ATOM 1420 O O . LEU A 1 187 ? -14.560 3.921 35.104 1.00 21.30 ? 187 LEU A O 1 ATOM 1421 C CB . LEU A 1 187 ? -17.192 4.702 33.665 1.00 19.86 ? 187 LEU A CB 1 ATOM 1422 C CG . LEU A 1 187 ? -18.427 4.398 32.801 1.00 21.76 ? 187 LEU A CG 1 ATOM 1423 C CD1 . LEU A 1 187 ? -18.528 5.329 31.555 1.00 21.55 ? 187 LEU A CD1 1 ATOM 1424 C CD2 . LEU A 1 187 ? -18.407 2.972 32.357 1.00 20.20 ? 187 LEU A CD2 1 ATOM 1425 N N . ASP A 1 188 ? -15.822 5.227 36.547 1.00 21.55 ? 188 ASP A N 1 ATOM 1426 C CA . ASP A 1 188 ? -14.638 5.832 37.214 1.00 23.51 ? 188 ASP A CA 1 ATOM 1427 C C . ASP A 1 188 ? -15.067 6.546 38.501 1.00 21.64 ? 188 ASP A C 1 ATOM 1428 O O . ASP A 1 188 ? -15.169 7.781 38.516 1.00 20.18 ? 188 ASP A O 1 ATOM 1429 C CB . ASP A 1 188 ? -13.884 6.809 36.308 1.00 24.78 ? 188 ASP A CB 1 ATOM 1430 C CG . ASP A 1 188 ? -12.486 7.206 36.894 1.00 32.94 ? 188 ASP A CG 1 ATOM 1431 O OD1 . ASP A 1 188 ? -11.523 6.365 36.829 1.00 37.13 ? 188 ASP A OD1 1 ATOM 1432 O OD2 . ASP A 1 188 ? -12.337 8.372 37.402 1.00 38.72 ? 188 ASP A OD2 1 ATOM 1433 N N . PRO A 1 189 ? -15.329 5.760 39.580 1.00 20.26 ? 189 PRO A N 1 ATOM 1434 C CA . PRO A 1 189 ? -16.050 6.345 40.695 1.00 19.97 ? 189 PRO A CA 1 ATOM 1435 C C . PRO A 1 189 ? -15.179 7.344 41.414 1.00 19.96 ? 189 PRO A C 1 ATOM 1436 O O . PRO A 1 189 ? -13.956 7.171 41.483 1.00 19.60 ? 189 PRO A O 1 ATOM 1437 C CB . PRO A 1 189 ? -16.380 5.115 41.596 1.00 19.41 ? 189 PRO A CB 1 ATOM 1438 C CG . PRO A 1 189 ? -16.267 3.959 40.699 1.00 18.95 ? 189 PRO A CG 1 ATOM 1439 C CD . PRO A 1 189 ? -15.156 4.305 39.761 1.00 19.65 ? 189 PRO A CD 1 ATOM 1440 N N . GLY A 1 190 ? -15.783 8.391 41.943 1.00 20.98 ? 190 GLY A N 1 ATOM 1441 C CA . GLY A 1 190 ? -15.001 9.383 42.697 1.00 22.45 ? 190 GLY A CA 1 ATOM 1442 C C . GLY A 1 190 ? -15.672 9.700 44.021 1.00 23.23 ? 190 GLY A C 1 ATOM 1443 O O . GLY A 1 190 ? -15.401 10.734 44.601 1.00 24.85 ? 190 GLY A O 1 ATOM 1444 N N . THR A 1 191 ? -16.556 8.840 44.494 1.00 23.36 ? 191 THR A N 1 ATOM 1445 C CA . THR A 1 191 ? -17.311 9.139 45.696 1.00 24.87 ? 191 THR A CA 1 ATOM 1446 C C . THR A 1 191 ? -16.873 8.343 46.927 1.00 24.71 ? 191 THR A C 1 ATOM 1447 O O . THR A 1 191 ? -17.437 8.549 47.984 1.00 25.51 ? 191 THR A O 1 ATOM 1448 C CB . THR A 1 191 ? -18.856 8.870 45.518 1.00 25.34 ? 191 THR A CB 1 ATOM 1449 O OG1 . THR A 1 191 ? -19.075 7.545 44.975 1.00 27.06 ? 191 THR A OG1 1 ATOM 1450 C CG2 . THR A 1 191 ? -19.495 9.920 44.637 1.00 25.21 ? 191 THR A CG2 1 ATOM 1451 N N . CYS A 1 192 ? -15.942 7.400 46.789 1.00 24.90 ? 192 CYS A N 1 ATOM 1452 C CA . CYS A 1 192 ? -15.515 6.572 47.923 1.00 25.43 ? 192 CYS A CA 1 ATOM 1453 C C . CYS A 1 192 ? -14.473 7.351 48.733 1.00 25.83 ? 192 CYS A C 1 ATOM 1454 O O . CYS A 1 192 ? -13.304 7.209 48.548 1.00 25.42 ? 192 CYS A O 1 ATOM 1455 C CB . CYS A 1 192 ? -14.973 5.247 47.437 1.00 24.53 ? 192 CYS A CB 1 ATOM 1456 S SG . CYS A 1 192 ? -14.508 4.030 48.689 1.00 25.64 ? 192 CYS A SG 1 ATOM 1457 N N . THR A 1 193 ? -14.930 8.181 49.661 1.00 27.73 ? 193 THR A N 1 ATOM 1458 C CA . THR A 1 193 ? -14.047 9.147 50.378 1.00 28.05 ? 193 THR A CA 1 ATOM 1459 C C . THR A 1 193 ? -12.747 8.537 50.911 1.00 27.05 ? 193 THR A C 1 ATOM 1460 O O . THR A 1 193 ? -11.661 9.066 50.686 1.00 26.16 ? 193 THR A O 1 ATOM 1461 C CB . THR A 1 193 ? -14.836 9.864 51.524 1.00 29.29 ? 193 THR A CB 1 ATOM 1462 O OG1 . THR A 1 193 ? -16.180 10.165 51.074 1.00 30.64 ? 193 THR A OG1 1 ATOM 1463 C CG2 . THR A 1 193 ? -14.148 11.161 51.941 1.00 31.15 ? 193 THR A CG2 1 ATOM 1464 N N . VAL A 1 194 ? -12.846 7.393 51.592 1.00 27.02 ? 194 VAL A N 1 ATOM 1465 C CA . VAL A 1 194 ? -11.656 6.790 52.159 1.00 26.44 ? 194 VAL A CA 1 ATOM 1466 C C . VAL A 1 194 ? -10.674 6.333 51.057 1.00 27.02 ? 194 VAL A C 1 ATOM 1467 O O . VAL A 1 194 ? -9.455 6.558 51.197 1.00 26.35 ? 194 VAL A O 1 ATOM 1468 C CB . VAL A 1 194 ? -12.002 5.676 53.116 1.00 27.10 ? 194 VAL A CB 1 ATOM 1469 C CG1 . VAL A 1 194 ? -10.724 4.835 53.489 1.00 27.12 ? 194 VAL A CG1 1 ATOM 1470 C CG2 . VAL A 1 194 ? -12.720 6.258 54.355 1.00 26.72 ? 194 VAL A CG2 1 ATOM 1471 N N . PHE A 1 195 ? -11.185 5.716 49.968 1.00 26.38 ? 195 PHE A N 1 ATOM 1472 C CA . PHE A 1 195 ? -10.306 5.275 48.876 1.00 26.47 ? 195 PHE A CA 1 ATOM 1473 C C . PHE A 1 195 ? -9.696 6.506 48.187 1.00 27.78 ? 195 PHE A C 1 ATOM 1474 O O . PHE A 1 195 ? -8.517 6.525 47.844 1.00 27.82 ? 195 PHE A O 1 ATOM 1475 C CB . PHE A 1 195 ? -11.035 4.351 47.851 1.00 25.96 ? 195 PHE A CB 1 ATOM 1476 C CG . PHE A 1 195 ? -10.297 4.193 46.551 1.00 21.26 ? 195 PHE A CG 1 ATOM 1477 C CD1 . PHE A 1 195 ? -9.344 3.208 46.403 1.00 19.40 ? 195 PHE A CD1 1 ATOM 1478 C CD2 . PHE A 1 195 ? -10.524 5.087 45.482 1.00 19.97 ? 195 PHE A CD2 1 ATOM 1479 C CE1 . PHE A 1 195 ? -8.629 3.050 45.159 1.00 18.24 ? 195 PHE A CE1 1 ATOM 1480 C CE2 . PHE A 1 195 ? -9.819 4.973 44.288 1.00 15.48 ? 195 PHE A CE2 1 ATOM 1481 C CZ . PHE A 1 195 ? -8.863 3.949 44.128 1.00 17.17 ? 195 PHE A CZ 1 ATOM 1482 N N . GLU A 1 196 ? -10.493 7.539 47.990 1.00 29.31 ? 196 GLU A N 1 ATOM 1483 C CA . GLU A 1 196 ? -9.949 8.756 47.393 1.00 32.24 ? 196 GLU A CA 1 ATOM 1484 C C . GLU A 1 196 ? -8.767 9.353 48.187 1.00 33.53 ? 196 GLU A C 1 ATOM 1485 O O . GLU A 1 196 ? -7.858 9.935 47.620 1.00 34.28 ? 196 GLU A O 1 ATOM 1486 C CB . GLU A 1 196 ? -11.086 9.763 47.165 1.00 32.89 ? 196 GLU A CB 1 ATOM 1487 C CG . GLU A 1 196 ? -12.163 9.241 46.120 1.00 33.12 ? 196 GLU A CG 1 ATOM 1488 C CD . GLU A 1 196 ? -11.581 9.021 44.715 1.00 34.53 ? 196 GLU A CD 1 ATOM 1489 O OE1 . GLU A 1 196 ? -10.679 9.794 44.340 1.00 36.25 ? 196 GLU A OE1 1 ATOM 1490 O OE2 . GLU A 1 196 ? -12.006 8.088 43.984 1.00 33.12 ? 196 GLU A OE2 1 ATOM 1491 N N . ASP A 1 197 ? -8.768 9.160 49.500 1.00 34.80 ? 197 ASP A N 1 ATOM 1492 C CA . ASP A 1 197 ? -7.678 9.653 50.353 1.00 36.07 ? 197 ASP A CA 1 ATOM 1493 C C . ASP A 1 197 ? -6.446 8.727 50.449 1.00 35.90 ? 197 ASP A C 1 ATOM 1494 O O . ASP A 1 197 ? -5.385 9.202 50.871 1.00 36.01 ? 197 ASP A O 1 ATOM 1495 C CB . ASP A 1 197 ? -8.197 9.951 51.764 1.00 36.44 ? 197 ASP A CB 1 ATOM 1496 C CG . ASP A 1 197 ? -8.974 11.255 51.850 1.00 39.03 ? 197 ASP A CG 1 ATOM 1497 O OD1 . ASP A 1 197 ? -8.913 12.070 50.894 1.00 43.38 ? 197 ASP A OD1 1 ATOM 1498 O OD2 . ASP A 1 197 ? -9.646 11.466 52.890 1.00 42.40 ? 197 ASP A OD2 1 ATOM 1499 N N . SER A 1 198 ? -6.586 7.445 50.062 1.00 34.92 ? 198 SER A N 1 ATOM 1500 C CA . SER A 1 198 ? -5.496 6.436 50.105 1.00 34.36 ? 198 SER A CA 1 ATOM 1501 C C . SER A 1 198 ? -4.140 6.963 49.621 1.00 34.86 ? 198 SER A C 1 ATOM 1502 O O . SER A 1 198 ? -4.063 7.742 48.642 1.00 34.27 ? 198 SER A O 1 ATOM 1503 C CB . SER A 1 198 ? -5.861 5.207 49.250 1.00 34.26 ? 198 SER A CB 1 ATOM 1504 O OG . SER A 1 198 ? -4.838 4.212 49.246 1.00 33.43 ? 198 SER A OG 1 ATOM 1505 N N . GLU A 1 199 ? -3.072 6.506 50.279 1.00 34.39 ? 199 GLU A N 1 ATOM 1506 C CA . GLU A 1 199 ? -1.715 6.897 49.887 1.00 34.90 ? 199 GLU A CA 1 ATOM 1507 C C . GLU A 1 199 ? -0.811 5.687 49.629 1.00 33.94 ? 199 GLU A C 1 ATOM 1508 O O . GLU A 1 199 ? 0.385 5.856 49.343 1.00 35.62 ? 199 GLU A O 1 ATOM 1509 C CB . GLU A 1 199 ? -1.094 7.872 50.927 1.00 35.75 ? 199 GLU A CB 1 ATOM 1510 N N . LEU A 1 200 ? -1.376 4.479 49.724 1.00 32.40 ? 200 LEU A N 1 ATOM 1511 C CA . LEU A 1 200 ? -0.670 3.221 49.457 1.00 30.45 ? 200 LEU A CA 1 ATOM 1512 C C . LEU A 1 200 ? 0.165 3.203 48.160 1.00 30.38 ? 200 LEU A C 1 ATOM 1513 O O . LEU A 1 200 ? 1.293 2.652 48.133 1.00 29.58 ? 200 LEU A O 1 ATOM 1514 C CB . LEU A 1 200 ? -1.652 2.055 49.501 1.00 29.97 ? 200 LEU A CB 1 ATOM 1515 C CG . LEU A 1 200 ? -1.011 0.671 49.371 1.00 30.68 ? 200 LEU A CG 1 ATOM 1516 C CD1 . LEU A 1 200 ? -0.001 0.366 50.523 1.00 29.88 ? 200 LEU A CD1 1 ATOM 1517 C CD2 . LEU A 1 200 ? -2.052 -0.413 49.248 1.00 29.15 ? 200 LEU A CD2 1 ATOM 1518 N N . ALA A 1 201 ? -0.369 3.828 47.100 1.00 29.89 ? 201 ALA A N 1 ATOM 1519 C CA . ALA A 1 201 ? 0.283 3.788 45.768 1.00 30.40 ? 201 ALA A CA 1 ATOM 1520 C C . ALA A 1 201 ? 1.558 4.587 45.770 1.00 30.21 ? 201 ALA A C 1 ATOM 1521 O O . ALA A 1 201 ? 2.588 4.125 45.267 1.00 29.04 ? 201 ALA A O 1 ATOM 1522 C CB . ALA A 1 201 ? -0.686 4.280 44.582 1.00 29.84 ? 201 ALA A CB 1 ATOM 1523 N N . ASP A 1 202 ? 1.467 5.796 46.328 1.00 31.73 ? 202 ASP A N 1 ATOM 1524 C CA . ASP A 1 202 ? 2.606 6.714 46.482 1.00 32.46 ? 202 ASP A CA 1 ATOM 1525 C C . ASP A 1 202 ? 3.774 6.048 47.254 1.00 32.15 ? 202 ASP A C 1 ATOM 1526 O O . ASP A 1 202 ? 4.962 6.096 46.841 1.00 31.92 ? 202 ASP A O 1 ATOM 1527 C CB . ASP A 1 202 ? 2.126 8.004 47.170 1.00 32.80 ? 202 ASP A CB 1 ATOM 1528 C CG . ASP A 1 202 ? 1.272 8.883 46.245 1.00 36.61 ? 202 ASP A CG 1 ATOM 1529 O OD1 . ASP A 1 202 ? 1.302 8.631 45.024 1.00 40.83 ? 202 ASP A OD1 1 ATOM 1530 O OD2 . ASP A 1 202 ? 0.595 9.833 46.716 1.00 40.66 ? 202 ASP A OD2 1 ATOM 1531 N N . THR A 1 203 ? 3.424 5.419 48.370 1.00 31.81 ? 203 THR A N 1 ATOM 1532 C CA . THR A 1 203 ? 4.402 4.707 49.184 1.00 31.74 ? 203 THR A CA 1 ATOM 1533 C C . THR A 1 203 ? 5.112 3.684 48.356 1.00 31.73 ? 203 THR A C 1 ATOM 1534 O O . THR A 1 203 ? 6.358 3.710 48.275 1.00 31.78 ? 203 THR A O 1 ATOM 1535 C CB . THR A 1 203 ? 3.706 3.999 50.305 1.00 31.39 ? 203 THR A CB 1 ATOM 1536 O OG1 . THR A 1 203 ? 3.002 4.981 51.062 1.00 32.72 ? 203 THR A OG1 1 ATOM 1537 C CG2 . THR A 1 203 ? 4.697 3.262 51.197 1.00 33.23 ? 203 THR A CG2 1 ATOM 1538 N N . VAL A 1 204 ? 4.329 2.779 47.744 1.00 31.91 ? 204 VAL A N 1 ATOM 1539 C CA . VAL A 1 204 ? 4.877 1.744 46.877 1.00 31.48 ? 204 VAL A CA 1 ATOM 1540 C C . VAL A 1 204 ? 5.701 2.309 45.720 1.00 30.92 ? 204 VAL A C 1 ATOM 1541 O O . VAL A 1 204 ? 6.755 1.784 45.413 1.00 30.10 ? 204 VAL A O 1 ATOM 1542 C CB . VAL A 1 204 ? 3.810 0.845 46.291 1.00 32.43 ? 204 VAL A CB 1 ATOM 1543 C CG1 . VAL A 1 204 ? 4.462 -0.161 45.306 1.00 31.62 ? 204 VAL A CG1 1 ATOM 1544 C CG2 . VAL A 1 204 ? 3.004 0.127 47.419 1.00 31.03 ? 204 VAL A CG2 1 ATOM 1545 N N . GLU A 1 205 ? 5.207 3.377 45.104 1.00 30.81 ? 205 GLU A N 1 ATOM 1546 C CA . GLU A 1 205 ? 5.893 4.014 44.024 1.00 30.68 ? 205 GLU A CA 1 ATOM 1547 C C . GLU A 1 205 ? 7.274 4.392 44.536 1.00 30.76 ? 205 GLU A C 1 ATOM 1548 O O . GLU A 1 205 ? 8.279 3.996 43.936 1.00 30.05 ? 205 GLU A O 1 ATOM 1549 C CB . GLU A 1 205 ? 5.161 5.262 43.525 1.00 30.51 ? 205 GLU A CB 1 ATOM 1550 C CG . GLU A 1 205 ? 6.056 6.096 42.566 1.00 33.25 ? 205 GLU A CG 1 ATOM 1551 C CD . GLU A 1 205 ? 5.324 7.124 41.681 1.00 35.64 ? 205 GLU A CD 1 ATOM 1552 O OE1 . GLU A 1 205 ? 4.143 7.418 41.925 1.00 36.37 ? 205 GLU A OE1 1 ATOM 1553 O OE2 . GLU A 1 205 ? 5.946 7.641 40.718 1.00 37.75 ? 205 GLU A OE2 1 ATOM 1554 N N . ALA A 1 206 ? 7.321 5.131 45.648 1.00 30.57 ? 206 ALA A N 1 ATOM 1555 C CA . ALA A 1 206 ? 8.610 5.641 46.180 1.00 30.12 ? 206 ALA A CA 1 ATOM 1556 C C . ALA A 1 206 ? 9.509 4.478 46.560 1.00 30.27 ? 206 ALA A C 1 ATOM 1557 O O . ALA A 1 206 ? 10.675 4.450 46.182 1.00 29.55 ? 206 ALA A O 1 ATOM 1558 C CB . ALA A 1 206 ? 8.398 6.590 47.367 1.00 29.23 ? 206 ALA A CB 1 ATOM 1559 N N . ASN A 1 207 ? 8.963 3.480 47.263 1.00 30.35 ? 207 ASN A N 1 ATOM 1560 C CA . ASN A 1 207 ? 9.831 2.408 47.700 1.00 31.02 ? 207 ASN A CA 1 ATOM 1561 C C . ASN A 1 207 ? 10.487 1.757 46.512 1.00 31.14 ? 207 ASN A C 1 ATOM 1562 O O . ASN A 1 207 ? 11.702 1.567 46.529 1.00 32.24 ? 207 ASN A O 1 ATOM 1563 C CB . ASN A 1 207 ? 9.157 1.385 48.638 1.00 32.11 ? 207 ASN A CB 1 ATOM 1564 C CG . ASN A 1 207 ? 8.667 2.030 49.990 1.00 35.72 ? 207 ASN A CG 1 ATOM 1565 O OD1 . ASN A 1 207 ? 8.957 3.211 50.295 1.00 38.99 ? 207 ASN A OD1 1 ATOM 1566 N ND2 . ASN A 1 207 ? 7.897 1.253 50.772 1.00 36.38 ? 207 ASN A ND2 1 ATOM 1567 N N . PHE A 1 208 ? 9.721 1.474 45.453 1.00 30.05 ? 208 PHE A N 1 ATOM 1568 C CA . PHE A 1 208 ? 10.303 0.796 44.301 1.00 28.23 ? 208 PHE A CA 1 ATOM 1569 C C . PHE A 1 208 ? 11.182 1.703 43.448 1.00 27.59 ? 208 PHE A C 1 ATOM 1570 O O . PHE A 1 208 ? 12.144 1.227 42.894 1.00 25.52 ? 208 PHE A O 1 ATOM 1571 C CB . PHE A 1 208 ? 9.240 0.095 43.437 1.00 28.69 ? 208 PHE A CB 1 ATOM 1572 C CG . PHE A 1 208 ? 9.825 -0.748 42.321 1.00 27.56 ? 208 PHE A CG 1 ATOM 1573 C CD1 . PHE A 1 208 ? 10.396 -2.004 42.591 1.00 25.22 ? 208 PHE A CD1 1 ATOM 1574 C CD2 . PHE A 1 208 ? 9.820 -0.278 40.997 1.00 28.00 ? 208 PHE A CD2 1 ATOM 1575 C CE1 . PHE A 1 208 ? 10.964 -2.797 41.566 1.00 22.27 ? 208 PHE A CE1 1 ATOM 1576 C CE2 . PHE A 1 208 ? 10.385 -1.079 39.966 1.00 26.70 ? 208 PHE A CE2 1 ATOM 1577 C CZ . PHE A 1 208 ? 10.957 -2.321 40.257 1.00 21.95 ? 208 PHE A CZ 1 ATOM 1578 N N . THR A 1 209 ? 10.853 2.995 43.354 1.00 28.01 ? 209 THR A N 1 ATOM 1579 C CA . THR A 1 209 ? 11.643 3.851 42.516 1.00 29.96 ? 209 THR A CA 1 ATOM 1580 C C . THR A 1 209 ? 13.049 3.964 43.111 1.00 30.85 ? 209 THR A C 1 ATOM 1581 O O . THR A 1 209 ? 14.038 3.912 42.385 1.00 30.81 ? 209 THR A O 1 ATOM 1582 C CB . THR A 1 209 ? 11.001 5.228 42.148 1.00 30.61 ? 209 THR A CB 1 ATOM 1583 O OG1 . THR A 1 209 ? 11.070 6.123 43.243 1.00 32.13 ? 209 THR A OG1 1 ATOM 1584 C CG2 . THR A 1 209 ? 9.575 5.121 41.748 1.00 30.39 ? 209 THR A CG2 1 ATOM 1585 N N . ALA A 1 210 ? 13.127 4.035 44.438 1.00 31.88 ? 210 ALA A N 1 ATOM 1586 C CA . ALA A 1 210 ? 14.415 4.009 45.154 1.00 32.99 ? 210 ALA A CA 1 ATOM 1587 C C . ALA A 1 210 ? 15.296 2.777 44.871 1.00 33.06 ? 210 ALA A C 1 ATOM 1588 O O . ALA A 1 210 ? 16.500 2.838 45.115 1.00 33.51 ? 210 ALA A O 1 ATOM 1589 C CB . ALA A 1 210 ? 14.238 4.232 46.672 1.00 32.69 ? 210 ALA A CB 1 ATOM 1590 N N . THR A 1 211 ? 14.731 1.694 44.334 1.00 32.37 ? 211 THR A N 1 ATOM 1591 C CA . THR A 1 211 ? 15.557 0.548 44.021 1.00 32.52 ? 211 THR A CA 1 ATOM 1592 C C . THR A 1 211 ? 16.233 0.533 42.633 1.00 32.26 ? 211 THR A C 1 ATOM 1593 O O . THR A 1 211 ? 17.059 -0.370 42.354 1.00 32.35 ? 211 THR A O 1 ATOM 1594 C CB . THR A 1 211 ? 14.843 -0.784 44.125 1.00 32.56 ? 211 THR A CB 1 ATOM 1595 O OG1 . THR A 1 211 ? 14.140 -1.000 42.918 1.00 35.05 ? 211 THR A OG1 1 ATOM 1596 C CG2 . THR A 1 211 ? 13.895 -0.881 45.348 1.00 34.09 ? 211 THR A CG2 1 ATOM 1597 N N . PHE A 1 212 ? 15.869 1.450 41.736 1.00 30.87 ? 212 PHE A N 1 ATOM 1598 C CA . PHE A 1 212 ? 16.480 1.399 40.381 1.00 29.14 ? 212 PHE A CA 1 ATOM 1599 C C . PHE A 1 212 ? 16.692 2.750 39.762 1.00 27.53 ? 212 PHE A C 1 ATOM 1600 O O . PHE A 1 212 ? 17.532 2.871 38.871 1.00 27.40 ? 212 PHE A O 1 ATOM 1601 C CB . PHE A 1 212 ? 15.695 0.474 39.409 1.00 29.42 ? 212 PHE A CB 1 ATOM 1602 C CG . PHE A 1 212 ? 14.481 1.125 38.813 1.00 29.31 ? 212 PHE A CG 1 ATOM 1603 C CD1 . PHE A 1 212 ? 13.253 1.078 39.493 1.00 26.23 ? 212 PHE A CD1 1 ATOM 1604 C CD2 . PHE A 1 212 ? 14.576 1.825 37.589 1.00 28.81 ? 212 PHE A CD2 1 ATOM 1605 C CE1 . PHE A 1 212 ? 12.150 1.704 38.980 1.00 27.29 ? 212 PHE A CE1 1 ATOM 1606 C CE2 . PHE A 1 212 ? 13.459 2.457 37.042 1.00 28.89 ? 212 PHE A CE2 1 ATOM 1607 C CZ . PHE A 1 212 ? 12.250 2.415 37.732 1.00 29.03 ? 212 PHE A CZ 1 ATOM 1608 N N . VAL A 1 213 ? 15.948 3.753 40.217 1.00 26.08 ? 213 VAL A N 1 ATOM 1609 C CA . VAL A 1 213 ? 16.117 5.107 39.676 1.00 25.73 ? 213 VAL A CA 1 ATOM 1610 C C . VAL A 1 213 ? 17.437 5.844 40.035 1.00 27.00 ? 213 VAL A C 1 ATOM 1611 O O . VAL A 1 213 ? 18.009 6.495 39.157 1.00 27.55 ? 213 VAL A O 1 ATOM 1612 C CB . VAL A 1 213 ? 14.890 5.978 39.932 1.00 24.68 ? 213 VAL A CB 1 ATOM 1613 C CG1 . VAL A 1 213 ? 15.082 7.410 39.407 1.00 23.07 ? 213 VAL A CG1 1 ATOM 1614 C CG2 . VAL A 1 213 ? 13.677 5.351 39.275 1.00 24.04 ? 213 VAL A CG2 1 ATOM 1615 N N . PRO A 1 214 ? 17.908 5.784 41.318 1.00 27.91 ? 214 PRO A N 1 ATOM 1616 C CA . PRO A 1 214 ? 19.215 6.418 41.681 1.00 27.49 ? 214 PRO A CA 1 ATOM 1617 C C . PRO A 1 214 ? 20.404 6.084 40.737 1.00 27.34 ? 214 PRO A C 1 ATOM 1618 O O . PRO A 1 214 ? 21.148 6.954 40.399 1.00 26.16 ? 214 PRO A O 1 ATOM 1619 C CB . PRO A 1 214 ? 19.499 5.868 43.098 1.00 26.85 ? 214 PRO A CB 1 ATOM 1620 C CG . PRO A 1 214 ? 18.135 5.550 43.677 1.00 28.27 ? 214 PRO A CG 1 ATOM 1621 C CD . PRO A 1 214 ? 17.294 5.082 42.478 1.00 27.75 ? 214 PRO A CD 1 ATOM 1622 N N . SER A 1 215 ? 20.581 4.830 40.327 1.00 28.76 ? 215 SER A N 1 ATOM 1623 C CA . SER A 1 215 ? 21.608 4.491 39.324 1.00 29.54 ? 215 SER A CA 1 ATOM 1624 C C . SER A 1 215 ? 21.450 5.268 38.036 1.00 29.89 ? 215 SER A C 1 ATOM 1625 O O . SER A 1 215 ? 22.447 5.645 37.407 1.00 30.45 ? 215 SER A O 1 ATOM 1626 C CB . SER A 1 215 ? 21.502 3.033 38.943 1.00 30.00 ? 215 SER A CB 1 ATOM 1627 O OG . SER A 1 215 ? 21.962 2.234 39.990 1.00 33.79 ? 215 SER A OG 1 ATOM 1628 N N . ILE A 1 216 ? 20.192 5.474 37.621 1.00 29.30 ? 216 ILE A N 1 ATOM 1629 C CA . ILE A 1 216 ? 19.933 6.176 36.384 1.00 28.84 ? 216 ILE A CA 1 ATOM 1630 C C . ILE A 1 216 ? 20.212 7.624 36.631 1.00 29.18 ? 216 ILE A C 1 ATOM 1631 O O . ILE A 1 216 ? 20.986 8.230 35.905 1.00 29.59 ? 216 ILE A O 1 ATOM 1632 C CB . ILE A 1 216 ? 18.484 5.996 35.858 1.00 29.11 ? 216 ILE A CB 1 ATOM 1633 C CG1 . ILE A 1 216 ? 18.145 4.503 35.731 1.00 28.23 ? 216 ILE A CG1 1 ATOM 1634 C CG2 . ILE A 1 216 ? 18.356 6.708 34.528 1.00 25.68 ? 216 ILE A CG2 1 ATOM 1635 C CD1 . ILE A 1 216 ? 16.686 4.189 35.437 1.00 29.44 ? 216 ILE A CD1 1 ATOM 1636 N N . ARG A 1 217 ? 19.620 8.172 37.689 1.00 28.89 ? 217 ARG A N 1 ATOM 1637 C CA . ARG A 1 217 ? 19.945 9.547 38.096 1.00 29.88 ? 217 ARG A CA 1 ATOM 1638 C C . ARG A 1 217 ? 21.460 9.813 38.037 1.00 30.22 ? 217 ARG A C 1 ATOM 1639 O O . ARG A 1 217 ? 21.920 10.839 37.530 1.00 31.01 ? 217 ARG A O 1 ATOM 1640 C CB . ARG A 1 217 ? 19.385 9.833 39.498 1.00 28.73 ? 217 ARG A CB 1 ATOM 1641 C CG . ARG A 1 217 ? 19.146 11.285 39.795 1.00 29.57 ? 217 ARG A CG 1 ATOM 1642 C CD . ARG A 1 217 ? 20.162 11.822 40.810 1.00 30.37 ? 217 ARG A CD 1 ATOM 1643 N NE . ARG A 1 217 ? 20.336 10.858 41.902 1.00 30.88 ? 217 ARG A NE 1 ATOM 1644 C CZ . ARG A 1 217 ? 21.501 10.569 42.468 1.00 24.82 ? 217 ARG A CZ 1 ATOM 1645 N NH1 . ARG A 1 217 ? 22.586 11.174 42.052 1.00 21.92 ? 217 ARG A NH1 1 ATOM 1646 N NH2 . ARG A 1 217 ? 21.577 9.650 43.412 1.00 25.17 ? 217 ARG A NH2 1 ATOM 1647 N N . GLN A 1 218 ? 22.231 8.890 38.557 1.00 30.44 ? 218 GLN A N 1 ATOM 1648 C CA . GLN A 1 218 ? 23.663 9.111 38.632 1.00 32.63 ? 218 GLN A CA 1 ATOM 1649 C C . GLN A 1 218 ? 24.308 9.256 37.240 1.00 31.36 ? 218 GLN A C 1 ATOM 1650 O O . GLN A 1 218 ? 25.027 10.226 36.979 1.00 30.72 ? 218 GLN A O 1 ATOM 1651 C CB . GLN A 1 218 ? 24.307 7.977 39.432 1.00 32.57 ? 218 GLN A CB 1 ATOM 1652 C CG . GLN A 1 218 ? 25.713 8.277 39.869 1.00 38.31 ? 218 GLN A CG 1 ATOM 1653 C CD . GLN A 1 218 ? 26.103 7.457 41.097 1.00 44.34 ? 218 GLN A CD 1 ATOM 1654 O OE1 . GLN A 1 218 ? 25.997 6.204 41.116 1.00 44.28 ? 218 GLN A OE1 1 ATOM 1655 N NE2 . GLN A 1 218 ? 26.542 8.164 42.138 1.00 44.50 ? 218 GLN A NE2 1 ATOM 1656 N N . ARG A 1 219 ? 24.013 8.289 36.370 1.00 31.21 ? 219 ARG A N 1 ATOM 1657 C CA . ARG A 1 219 ? 24.483 8.281 34.995 1.00 31.37 ? 219 ARG A CA 1 ATOM 1658 C C . ARG A 1 219 ? 24.045 9.532 34.264 1.00 32.03 ? 219 ARG A C 1 ATOM 1659 O O . ARG A 1 219 ? 24.857 10.113 33.536 1.00 32.38 ? 219 ARG A O 1 ATOM 1660 C CB . ARG A 1 219 ? 24.053 7.023 34.241 1.00 31.04 ? 219 ARG A CB 1 ATOM 1661 C CG . ARG A 1 219 ? 24.757 6.849 32.885 1.00 32.17 ? 219 ARG A CG 1 ATOM 1662 C CD . ARG A 1 219 ? 24.156 5.656 32.048 1.00 32.70 ? 219 ARG A CD 1 ATOM 1663 N NE . ARG A 1 219 ? 22.709 5.788 31.761 1.00 32.64 ? 219 ARG A NE 1 ATOM 1664 C CZ . ARG A 1 219 ? 21.763 4.930 32.172 1.00 33.36 ? 219 ARG A CZ 1 ATOM 1665 N NH1 . ARG A 1 219 ? 22.070 3.861 32.916 1.00 32.49 ? 219 ARG A NH1 1 ATOM 1666 N NH2 . ARG A 1 219 ? 20.489 5.130 31.849 1.00 34.05 ? 219 ARG A NH2 1 ATOM 1667 N N . LEU A 1 220 ? 22.799 9.978 34.459 1.00 31.01 ? 220 LEU A N 1 ATOM 1668 C CA . LEU A 1 220 ? 22.405 11.201 33.773 1.00 31.45 ? 220 LEU A CA 1 ATOM 1669 C C . LEU A 1 220 ? 23.202 12.424 34.231 1.00 31.75 ? 220 LEU A C 1 ATOM 1670 O O . LEU A 1 220 ? 23.558 13.282 33.405 1.00 31.18 ? 220 LEU A O 1 ATOM 1671 C CB . LEU A 1 220 ? 20.887 11.474 33.831 1.00 30.75 ? 220 LEU A CB 1 ATOM 1672 C CG . LEU A 1 220 ? 19.938 10.385 33.296 1.00 32.09 ? 220 LEU A CG 1 ATOM 1673 C CD1 . LEU A 1 220 ? 18.431 10.668 33.659 1.00 29.86 ? 220 LEU A CD1 1 ATOM 1674 C CD2 . LEU A 1 220 ? 20.132 10.147 31.787 1.00 27.40 ? 220 LEU A CD2 1 ATOM 1675 N N . GLU A 1 221 ? 23.470 12.530 35.528 1.00 32.21 ? 221 GLU A N 1 ATOM 1676 C CA . GLU A 1 221 ? 24.188 13.708 36.045 1.00 33.71 ? 221 GLU A CA 1 ATOM 1677 C C . GLU A 1 221 ? 25.643 13.658 35.589 1.00 33.95 ? 221 GLU A C 1 ATOM 1678 O O . GLU A 1 221 ? 26.220 14.672 35.277 1.00 34.04 ? 221 GLU A O 1 ATOM 1679 C CB . GLU A 1 221 ? 24.079 13.833 37.571 1.00 33.77 ? 221 GLU A CB 1 ATOM 1680 C CG . GLU A 1 221 ? 22.654 14.145 38.089 1.00 34.80 ? 221 GLU A CG 1 ATOM 1681 C CD . GLU A 1 221 ? 22.604 14.205 39.606 1.00 38.27 ? 221 GLU A CD 1 ATOM 1682 O OE1 . GLU A 1 221 ? 23.456 13.566 40.272 1.00 40.05 ? 221 GLU A OE1 1 ATOM 1683 O OE2 . GLU A 1 221 ? 21.730 14.900 40.128 1.00 38.34 ? 221 GLU A OE2 1 ATOM 1684 N N . ASN A 1 222 ? 26.178 12.451 35.509 1.00 35.22 ? 222 ASN A N 1 ATOM 1685 C CA . ASN A 1 222 ? 27.484 12.191 34.953 1.00 37.40 ? 222 ASN A CA 1 ATOM 1686 C C . ASN A 1 222 ? 27.656 12.656 33.524 1.00 37.99 ? 222 ASN A C 1 ATOM 1687 O O . ASN A 1 222 ? 28.698 13.242 33.194 1.00 37.37 ? 222 ASN A O 1 ATOM 1688 C CB . ASN A 1 222 ? 27.753 10.707 34.978 1.00 38.05 ? 222 ASN A CB 1 ATOM 1689 C CG . ASN A 1 222 ? 28.834 10.338 35.952 1.00 42.90 ? 222 ASN A CG 1 ATOM 1690 O OD1 . ASN A 1 222 ? 30.028 10.341 35.590 1.00 47.94 ? 222 ASN A OD1 1 ATOM 1691 N ND2 . ASN A 1 222 ? 28.440 9.986 37.195 1.00 43.75 ? 222 ASN A ND2 1 ATOM 1692 N N . ASP A 1 223 ? 26.648 12.367 32.685 1.00 38.07 ? 223 ASP A N 1 ATOM 1693 C CA . ASP A 1 223 ? 26.716 12.638 31.237 1.00 38.30 ? 223 ASP A CA 1 ATOM 1694 C C . ASP A 1 223 ? 26.375 14.094 30.897 1.00 38.07 ? 223 ASP A C 1 ATOM 1695 O O . ASP A 1 223 ? 26.873 14.649 29.910 1.00 38.21 ? 223 ASP A O 1 ATOM 1696 C CB . ASP A 1 223 ? 25.794 11.689 30.459 1.00 37.93 ? 223 ASP A CB 1 ATOM 1697 C CG . ASP A 1 223 ? 26.192 10.222 30.590 1.00 39.11 ? 223 ASP A CG 1 ATOM 1698 O OD1 . ASP A 1 223 ? 27.342 9.924 30.974 1.00 39.72 ? 223 ASP A OD1 1 ATOM 1699 O OD2 . ASP A 1 223 ? 25.341 9.338 30.295 1.00 41.61 ? 223 ASP A OD2 1 ATOM 1700 N N . LEU A 1 224 ? 25.515 14.696 31.705 1.00 37.70 ? 224 LEU A N 1 ATOM 1701 C CA . LEU A 1 224 ? 25.118 16.074 31.529 1.00 37.37 ? 224 LEU A CA 1 ATOM 1702 C C . LEU A 1 224 ? 25.694 16.936 32.644 1.00 37.60 ? 224 LEU A C 1 ATOM 1703 O O . LEU A 1 224 ? 24.964 17.327 33.558 1.00 37.57 ? 224 LEU A O 1 ATOM 1704 C CB . LEU A 1 224 ? 23.600 16.185 31.534 1.00 37.31 ? 224 LEU A CB 1 ATOM 1705 C CG . LEU A 1 224 ? 22.801 15.607 30.348 1.00 38.93 ? 224 LEU A CG 1 ATOM 1706 C CD1 . LEU A 1 224 ? 21.413 15.026 30.806 1.00 36.76 ? 224 LEU A CD1 1 ATOM 1707 C CD2 . LEU A 1 224 ? 22.612 16.653 29.235 1.00 35.28 ? 224 LEU A CD2 1 ATOM 1708 N N . SER A 1 225 ? 26.997 17.234 32.568 1.00 37.57 ? 225 SER A N 1 ATOM 1709 C CA . SER A 1 225 ? 27.664 18.105 33.551 1.00 38.05 ? 225 SER A CA 1 ATOM 1710 C C . SER A 1 225 ? 26.958 19.399 33.791 1.00 37.26 ? 225 SER A C 1 ATOM 1711 O O . SER A 1 225 ? 26.649 20.123 32.864 1.00 38.27 ? 225 SER A O 1 ATOM 1712 C CB . SER A 1 225 ? 29.103 18.438 33.139 1.00 38.96 ? 225 SER A CB 1 ATOM 1713 O OG . SER A 1 225 ? 29.969 17.317 33.374 1.00 42.71 ? 225 SER A OG 1 ATOM 1714 N N . GLY A 1 226 ? 26.753 19.724 35.049 1.00 36.58 ? 226 GLY A N 1 ATOM 1715 C CA . GLY A 1 226 ? 26.086 20.971 35.411 1.00 36.10 ? 226 GLY A CA 1 ATOM 1716 C C . GLY A 1 226 ? 24.646 20.729 35.814 1.00 35.20 ? 226 GLY A C 1 ATOM 1717 O O . GLY A 1 226 ? 23.963 21.606 36.348 1.00 36.47 ? 226 GLY A O 1 ATOM 1718 N N . VAL A 1 227 ? 24.185 19.515 35.582 1.00 34.54 ? 227 VAL A N 1 ATOM 1719 C CA . VAL A 1 227 ? 22.790 19.184 35.845 1.00 33.20 ? 227 VAL A CA 1 ATOM 1720 C C . VAL A 1 227 ? 22.623 18.409 37.154 1.00 32.58 ? 227 VAL A C 1 ATOM 1721 O O . VAL A 1 227 ? 23.447 17.542 37.500 1.00 31.59 ? 227 VAL A O 1 ATOM 1722 C CB . VAL A 1 227 ? 22.219 18.398 34.630 1.00 33.74 ? 227 VAL A CB 1 ATOM 1723 C CG1 . VAL A 1 227 ? 21.299 17.222 35.050 1.00 32.08 ? 227 VAL A CG1 1 ATOM 1724 C CG2 . VAL A 1 227 ? 21.551 19.386 33.641 1.00 31.93 ? 227 VAL A CG2 1 ATOM 1725 N N . THR A 1 228 ? 21.542 18.704 37.859 1.00 31.45 ? 228 THR A N 1 ATOM 1726 C CA . THR A 1 228 ? 21.239 17.990 39.085 1.00 31.84 ? 228 THR A CA 1 ATOM 1727 C C . THR A 1 228 ? 19.736 17.575 39.105 1.00 31.14 ? 228 THR A C 1 ATOM 1728 O O . THR A 1 228 ? 18.842 18.401 38.887 1.00 31.05 ? 228 THR A O 1 ATOM 1729 C CB . THR A 1 228 ? 21.780 18.801 40.344 1.00 32.35 ? 228 THR A CB 1 ATOM 1730 O OG1 . THR A 1 228 ? 20.755 18.953 41.324 1.00 35.04 ? 228 THR A OG1 1 ATOM 1731 C CG2 . THR A 1 228 ? 22.255 20.204 39.948 1.00 32.06 ? 228 THR A CG2 1 ATOM 1732 N N . LEU A 1 229 ? 19.463 16.289 39.319 1.00 29.77 ? 229 LEU A N 1 ATOM 1733 C CA . LEU A 1 229 ? 18.127 15.752 39.097 1.00 28.83 ? 229 LEU A CA 1 ATOM 1734 C C . LEU A 1 229 ? 17.570 15.046 40.319 1.00 28.78 ? 229 LEU A C 1 ATOM 1735 O O . LEU A 1 229 ? 18.333 14.400 41.087 1.00 28.78 ? 229 LEU A O 1 ATOM 1736 C CB . LEU A 1 229 ? 18.163 14.743 37.931 1.00 28.67 ? 229 LEU A CB 1 ATOM 1737 C CG . LEU A 1 229 ? 18.474 15.185 36.467 1.00 28.57 ? 229 LEU A CG 1 ATOM 1738 C CD1 . LEU A 1 229 ? 18.795 13.952 35.570 1.00 24.69 ? 229 LEU A CD1 1 ATOM 1739 C CD2 . LEU A 1 229 ? 17.382 16.041 35.887 1.00 22.82 ? 229 LEU A CD2 1 ATOM 1740 N N . THR A 1 230 ? 16.254 15.113 40.510 1.00 27.89 ? 230 THR A N 1 ATOM 1741 C CA . THR A 1 230 ? 15.655 14.248 41.527 1.00 27.61 ? 230 THR A CA 1 ATOM 1742 C C . THR A 1 230 ? 15.297 12.917 40.872 1.00 28.13 ? 230 THR A C 1 ATOM 1743 O O . THR A 1 230 ? 15.178 12.827 39.672 1.00 28.07 ? 230 THR A O 1 ATOM 1744 C CB . THR A 1 230 ? 14.379 14.822 42.175 1.00 27.27 ? 230 THR A CB 1 ATOM 1745 O OG1 . THR A 1 230 ? 13.348 14.872 41.202 1.00 26.87 ? 230 THR A OG1 1 ATOM 1746 C CG2 . THR A 1 230 ? 14.610 16.236 42.819 1.00 26.39 ? 230 THR A CG2 1 ATOM 1747 N N . ASP A 1 231 ? 15.141 11.879 41.664 1.00 28.80 ? 231 ASP A N 1 ATOM 1748 C CA . ASP A 1 231 ? 14.563 10.644 41.162 1.00 29.97 ? 231 ASP A CA 1 ATOM 1749 C C . ASP A 1 231 ? 13.258 10.896 40.364 1.00 30.08 ? 231 ASP A C 1 ATOM 1750 O O . ASP A 1 231 ? 13.050 10.312 39.291 1.00 30.71 ? 231 ASP A O 1 ATOM 1751 C CB . ASP A 1 231 ? 14.292 9.707 42.327 1.00 29.51 ? 231 ASP A CB 1 ATOM 1752 C CG . ASP A 1 231 ? 15.595 9.227 43.037 1.00 32.28 ? 231 ASP A CG 1 ATOM 1753 O OD1 . ASP A 1 231 ? 16.713 9.382 42.470 1.00 32.69 ? 231 ASP A OD1 1 ATOM 1754 O OD2 . ASP A 1 231 ? 15.480 8.652 44.167 1.00 33.94 ? 231 ASP A OD2 1 ATOM 1755 N N . THR A 1 232 ? 12.385 11.769 40.877 1.00 29.40 ? 232 THR A N 1 ATOM 1756 C CA . THR A 1 232 ? 11.113 11.978 40.238 1.00 28.11 ? 232 THR A CA 1 ATOM 1757 C C . THR A 1 232 ? 11.354 12.559 38.856 1.00 28.42 ? 232 THR A C 1 ATOM 1758 O O . THR A 1 232 ? 10.663 12.181 37.892 1.00 28.62 ? 232 THR A O 1 ATOM 1759 C CB . THR A 1 232 ? 10.147 12.831 41.098 1.00 28.32 ? 232 THR A CB 1 ATOM 1760 O OG1 . THR A 1 232 ? 9.855 12.089 42.289 1.00 27.11 ? 232 THR A OG1 1 ATOM 1761 C CG2 . THR A 1 232 ? 8.820 13.056 40.376 1.00 25.91 ? 232 THR A CG2 1 ATOM 1762 N N . GLU A 1 233 ? 12.357 13.441 38.746 1.00 27.46 ? 233 GLU A N 1 ATOM 1763 C CA . GLU A 1 233 ? 12.612 14.068 37.470 1.00 25.85 ? 233 GLU A CA 1 ATOM 1764 C C . GLU A 1 233 ? 13.086 13.050 36.456 1.00 25.20 ? 233 GLU A C 1 ATOM 1765 O O . GLU A 1 233 ? 12.791 13.172 35.282 1.00 25.38 ? 233 GLU A O 1 ATOM 1766 C CB . GLU A 1 233 ? 13.554 15.235 37.632 1.00 26.01 ? 233 GLU A CB 1 ATOM 1767 C CG . GLU A 1 233 ? 12.810 16.410 38.303 1.00 28.20 ? 233 GLU A CG 1 ATOM 1768 C CD . GLU A 1 233 ? 13.714 17.490 38.841 1.00 28.49 ? 233 GLU A CD 1 ATOM 1769 O OE1 . GLU A 1 233 ? 14.898 17.216 39.077 1.00 28.70 ? 233 GLU A OE1 1 ATOM 1770 O OE2 . GLU A 1 233 ? 13.231 18.621 39.023 1.00 30.62 ? 233 GLU A OE2 1 ATOM 1771 N N . VAL A 1 234 ? 13.789 12.028 36.903 1.00 23.95 ? 234 VAL A N 1 ATOM 1772 C CA . VAL A 1 234 ? 14.288 11.048 35.989 1.00 23.38 ? 234 VAL A CA 1 ATOM 1773 C C . VAL A 1 234 ? 13.087 10.306 35.419 1.00 23.76 ? 234 VAL A C 1 ATOM 1774 O O . VAL A 1 234 ? 13.086 10.014 34.236 1.00 23.48 ? 234 VAL A O 1 ATOM 1775 C CB . VAL A 1 234 ? 15.174 9.996 36.629 1.00 23.74 ? 234 VAL A CB 1 ATOM 1776 C CG1 . VAL A 1 234 ? 15.458 8.899 35.600 1.00 23.09 ? 234 VAL A CG1 1 ATOM 1777 C CG2 . VAL A 1 234 ? 16.492 10.606 37.149 1.00 24.12 ? 234 VAL A CG2 1 ATOM 1778 N N . THR A 1 235 ? 12.083 9.996 36.248 1.00 22.30 ? 235 THR A N 1 ATOM 1779 C CA . THR A 1 235 ? 10.933 9.348 35.702 1.00 22.09 ? 235 THR A CA 1 ATOM 1780 C C . THR A 1 235 ? 10.183 10.277 34.702 1.00 21.87 ? 235 THR A C 1 ATOM 1781 O O . THR A 1 235 ? 9.595 9.795 33.763 1.00 21.84 ? 235 THR A O 1 ATOM 1782 C CB . THR A 1 235 ? 9.995 8.740 36.783 1.00 21.65 ? 235 THR A CB 1 ATOM 1783 O OG1 . THR A 1 235 ? 9.281 9.781 37.415 1.00 21.05 ? 235 THR A OG1 1 ATOM 1784 C CG2 . THR A 1 235 ? 10.764 7.942 37.792 1.00 20.98 ? 235 THR A CG2 1 ATOM 1785 N N . TYR A 1 236 ? 10.248 11.593 34.857 1.00 22.08 ? 236 TYR A N 1 ATOM 1786 C CA . TYR A 1 236 ? 9.691 12.489 33.851 1.00 21.85 ? 236 TYR A CA 1 ATOM 1787 C C . TYR A 1 236 ? 10.359 12.299 32.489 1.00 22.66 ? 236 TYR A C 1 ATOM 1788 O O . TYR A 1 236 ? 9.682 12.216 31.480 1.00 23.32 ? 236 TYR A O 1 ATOM 1789 C CB . TYR A 1 236 ? 9.782 13.961 34.257 1.00 22.04 ? 236 TYR A CB 1 ATOM 1790 C CG . TYR A 1 236 ? 8.971 14.337 35.492 1.00 23.54 ? 236 TYR A CG 1 ATOM 1791 C CD1 . TYR A 1 236 ? 7.979 13.479 35.979 1.00 24.97 ? 236 TYR A CD1 1 ATOM 1792 C CD2 . TYR A 1 236 ? 9.195 15.552 36.172 1.00 23.17 ? 236 TYR A CD2 1 ATOM 1793 C CE1 . TYR A 1 236 ? 7.212 13.795 37.110 1.00 26.75 ? 236 TYR A CE1 1 ATOM 1794 C CE2 . TYR A 1 236 ? 8.419 15.898 37.322 1.00 23.84 ? 236 TYR A CE2 1 ATOM 1795 C CZ . TYR A 1 236 ? 7.426 14.992 37.778 1.00 27.68 ? 236 TYR A CZ 1 ATOM 1796 O OH . TYR A 1 236 ? 6.615 15.234 38.901 1.00 31.55 ? 236 TYR A OH 1 ATOM 1797 N N . LEU A 1 237 ? 11.687 12.257 32.431 1.00 22.85 ? 237 LEU A N 1 ATOM 1798 C CA . LEU A 1 237 ? 12.358 11.984 31.166 1.00 22.66 ? 237 LEU A CA 1 ATOM 1799 C C . LEU A 1 237 ? 12.073 10.601 30.637 1.00 23.30 ? 237 LEU A C 1 ATOM 1800 O O . LEU A 1 237 ? 12.258 10.342 29.450 1.00 24.03 ? 237 LEU A O 1 ATOM 1801 C CB . LEU A 1 237 ? 13.859 12.144 31.318 1.00 22.59 ? 237 LEU A CB 1 ATOM 1802 C CG . LEU A 1 237 ? 14.382 13.494 31.766 1.00 20.77 ? 237 LEU A CG 1 ATOM 1803 C CD1 . LEU A 1 237 ? 15.885 13.246 32.172 1.00 20.72 ? 237 LEU A CD1 1 ATOM 1804 C CD2 . LEU A 1 237 ? 14.176 14.658 30.693 1.00 16.54 ? 237 LEU A CD2 1 ATOM 1805 N N . MET A 1 238 ? 11.687 9.673 31.512 1.00 23.34 ? 238 MET A N 1 ATOM 1806 C CA . MET A 1 238 ? 11.287 8.359 31.025 1.00 23.53 ? 238 MET A CA 1 ATOM 1807 C C . MET A 1 238 ? 9.885 8.440 30.400 1.00 24.03 ? 238 MET A C 1 ATOM 1808 O O . MET A 1 238 ? 9.627 7.833 29.361 1.00 23.26 ? 238 MET A O 1 ATOM 1809 C CB . MET A 1 238 ? 11.422 7.263 32.101 1.00 23.48 ? 238 MET A CB 1 ATOM 1810 C CG . MET A 1 238 ? 12.914 7.056 32.545 1.00 21.95 ? 238 MET A CG 1 ATOM 1811 S SD . MET A 1 238 ? 13.056 5.607 33.569 1.00 23.54 ? 238 MET A SD 1 ATOM 1812 C CE . MET A 1 238 ? 13.330 4.262 32.381 1.00 16.41 ? 238 MET A CE 1 ATOM 1813 N N . ASP A 1 239 ? 9.018 9.241 31.016 1.00 24.34 ? 239 ASP A N 1 ATOM 1814 C CA . ASP A 1 239 ? 7.672 9.425 30.546 1.00 25.29 ? 239 ASP A CA 1 ATOM 1815 C C . ASP A 1 239 ? 7.718 10.058 29.132 1.00 25.68 ? 239 ASP A C 1 ATOM 1816 O O . ASP A 1 239 ? 6.970 9.678 28.224 1.00 26.21 ? 239 ASP A O 1 ATOM 1817 C CB . ASP A 1 239 ? 6.922 10.387 31.484 1.00 24.30 ? 239 ASP A CB 1 ATOM 1818 C CG . ASP A 1 239 ? 6.509 9.767 32.832 1.00 23.60 ? 239 ASP A CG 1 ATOM 1819 O OD1 . ASP A 1 239 ? 6.615 8.533 33.071 1.00 21.13 ? 239 ASP A OD1 1 ATOM 1820 O OD2 . ASP A 1 239 ? 6.033 10.571 33.677 1.00 25.92 ? 239 ASP A OD2 1 ATOM 1821 N N . MET A 1 240 ? 8.595 11.027 28.958 1.00 25.97 ? 240 MET A N 1 ATOM 1822 C CA . MET A 1 240 ? 8.749 11.707 27.660 1.00 27.09 ? 240 MET A CA 1 ATOM 1823 C C . MET A 1 240 ? 9.031 10.763 26.482 1.00 27.22 ? 240 MET A C 1 ATOM 1824 O O . MET A 1 240 ? 8.656 11.043 25.350 1.00 27.15 ? 240 MET A O 1 ATOM 1825 C CB . MET A 1 240 ? 9.828 12.804 27.742 1.00 27.30 ? 240 MET A CB 1 ATOM 1826 C CG . MET A 1 240 ? 9.339 13.993 28.517 1.00 26.32 ? 240 MET A CG 1 ATOM 1827 S SD . MET A 1 240 ? 7.855 14.692 27.754 1.00 29.27 ? 240 MET A SD 1 ATOM 1828 C CE . MET A 1 240 ? 8.651 15.440 26.305 1.00 25.95 ? 240 MET A CE 1 ATOM 1829 N N . CYS A 1 241 ? 9.665 9.634 26.750 1.00 26.67 ? 241 CYS A N 1 ATOM 1830 C CA . CYS A 1 241 ? 9.907 8.690 25.681 1.00 27.66 ? 241 CYS A CA 1 ATOM 1831 C C . CYS A 1 241 ? 8.555 8.196 25.024 1.00 28.20 ? 241 CYS A C 1 ATOM 1832 O O . CYS A 1 241 ? 8.434 8.082 23.812 1.00 28.17 ? 241 CYS A O 1 ATOM 1833 C CB . CYS A 1 241 ? 10.771 7.579 26.209 1.00 26.68 ? 241 CYS A CB 1 ATOM 1834 S SG . CYS A 1 241 ? 10.698 6.040 25.316 1.00 30.00 ? 241 CYS A SG 1 ATOM 1835 N N . SER A 1 242 ? 7.535 7.952 25.825 1.00 27.66 ? 242 SER A N 1 ATOM 1836 C CA . SER A 1 242 ? 6.273 7.576 25.256 1.00 27.39 ? 242 SER A CA 1 ATOM 1837 C C . SER A 1 242 ? 5.596 8.791 24.661 1.00 27.34 ? 242 SER A C 1 ATOM 1838 O O . SER A 1 242 ? 5.152 8.740 23.560 1.00 27.47 ? 242 SER A O 1 ATOM 1839 C CB . SER A 1 242 ? 5.356 6.937 26.291 1.00 26.70 ? 242 SER A CB 1 ATOM 1840 O OG . SER A 1 242 ? 4.019 7.001 25.829 1.00 25.78 ? 242 SER A OG 1 ATOM 1841 N N . PHE A 1 243 ? 5.505 9.878 25.403 1.00 27.52 ? 243 PHE A N 1 ATOM 1842 C CA . PHE A 1 243 ? 4.803 11.042 24.933 1.00 27.75 ? 243 PHE A CA 1 ATOM 1843 C C . PHE A 1 243 ? 5.434 11.719 23.735 1.00 29.00 ? 243 PHE A C 1 ATOM 1844 O O . PHE A 1 243 ? 4.708 12.230 22.896 1.00 29.91 ? 243 PHE A O 1 ATOM 1845 C CB . PHE A 1 243 ? 4.586 12.035 26.055 1.00 27.11 ? 243 PHE A CB 1 ATOM 1846 C CG . PHE A 1 243 ? 3.534 11.605 27.021 1.00 26.07 ? 243 PHE A CG 1 ATOM 1847 C CD1 . PHE A 1 243 ? 2.182 11.785 26.732 1.00 26.69 ? 243 PHE A CD1 1 ATOM 1848 C CD2 . PHE A 1 243 ? 3.884 11.014 28.217 1.00 25.33 ? 243 PHE A CD2 1 ATOM 1849 C CE1 . PHE A 1 243 ? 1.190 11.385 27.637 1.00 24.77 ? 243 PHE A CE1 1 ATOM 1850 C CE2 . PHE A 1 243 ? 2.894 10.588 29.128 1.00 24.73 ? 243 PHE A CE2 1 ATOM 1851 C CZ . PHE A 1 243 ? 1.556 10.771 28.822 1.00 24.27 ? 243 PHE A CZ 1 ATOM 1852 N N . ASP A 1 244 ? 6.759 11.727 23.643 1.00 29.63 ? 244 ASP A N 1 ATOM 1853 C CA . ASP A 1 244 ? 7.440 12.272 22.461 1.00 30.81 ? 244 ASP A CA 1 ATOM 1854 C C . ASP A 1 244 ? 7.453 11.296 21.272 1.00 32.37 ? 244 ASP A C 1 ATOM 1855 O O . ASP A 1 244 ? 7.748 11.700 20.151 1.00 33.47 ? 244 ASP A O 1 ATOM 1856 C CB . ASP A 1 244 ? 8.873 12.674 22.832 1.00 30.29 ? 244 ASP A CB 1 ATOM 1857 C CG . ASP A 1 244 ? 9.565 13.500 21.769 1.00 28.22 ? 244 ASP A CG 1 ATOM 1858 O OD1 . ASP A 1 244 ? 9.147 14.633 21.483 1.00 25.58 ? 244 ASP A OD1 1 ATOM 1859 O OD2 . ASP A 1 244 ? 10.593 13.034 21.259 1.00 28.07 ? 244 ASP A OD2 1 ATOM 1860 N N . THR A 1 245 ? 7.190 10.007 21.491 1.00 34.10 ? 245 THR A N 1 ATOM 1861 C CA . THR A 1 245 ? 7.067 9.093 20.356 1.00 35.20 ? 245 THR A CA 1 ATOM 1862 C C . THR A 1 245 ? 5.684 9.271 19.674 1.00 37.19 ? 245 THR A C 1 ATOM 1863 O O . THR A 1 245 ? 5.589 9.504 18.456 1.00 38.08 ? 245 THR A O 1 ATOM 1864 C CB . THR A 1 245 ? 7.302 7.650 20.754 1.00 35.37 ? 245 THR A CB 1 ATOM 1865 O OG1 . THR A 1 245 ? 8.659 7.486 21.185 1.00 34.24 ? 245 THR A OG1 1 ATOM 1866 C CG2 . THR A 1 245 ? 7.073 6.713 19.570 1.00 35.18 ? 245 THR A CG2 1 ATOM 1867 N N . ILE A 1 246 ? 4.620 9.246 20.465 1.00 37.88 ? 246 ILE A N 1 ATOM 1868 C CA . ILE A 1 246 ? 3.302 9.026 19.915 1.00 38.72 ? 246 ILE A CA 1 ATOM 1869 C C . ILE A 1 246 ? 2.440 10.284 19.776 1.00 40.03 ? 246 ILE A C 1 ATOM 1870 O O . ILE A 1 246 ? 1.224 10.217 19.569 1.00 40.60 ? 246 ILE A O 1 ATOM 1871 C CB . ILE A 1 246 ? 2.599 7.881 20.682 1.00 38.43 ? 246 ILE A CB 1 ATOM 1872 C CG1 . ILE A 1 246 ? 2.093 8.322 22.062 1.00 37.82 ? 246 ILE A CG1 1 ATOM 1873 C CG2 . ILE A 1 246 ? 3.525 6.657 20.792 1.00 36.69 ? 246 ILE A CG2 1 ATOM 1874 C CD1 . ILE A 1 246 ? 1.717 7.075 22.888 1.00 35.48 ? 246 ILE A CD1 1 ATOM 1875 N N . SER A 1 247 ? 3.099 11.426 19.900 1.00 41.93 ? 247 SER A N 1 ATOM 1876 C CA . SER A 1 247 ? 2.494 12.739 19.723 1.00 44.13 ? 247 SER A CA 1 ATOM 1877 C C . SER A 1 247 ? 2.764 13.281 18.339 1.00 45.02 ? 247 SER A C 1 ATOM 1878 O O . SER A 1 247 ? 2.184 14.270 17.926 1.00 46.32 ? 247 SER A O 1 ATOM 1879 C CB . SER A 1 247 ? 3.076 13.718 20.738 1.00 43.87 ? 247 SER A CB 1 ATOM 1880 O OG . SER A 1 247 ? 2.706 13.313 22.061 1.00 46.93 ? 247 SER A OG 1 ATOM 1881 N N . THR A 1 248 ? 3.654 12.632 17.626 1.00 46.51 ? 248 THR A N 1 ATOM 1882 C CA . THR A 1 248 ? 4.225 13.208 16.436 1.00 48.14 ? 248 THR A CA 1 ATOM 1883 C C . THR A 1 248 ? 3.726 12.490 15.190 1.00 48.41 ? 248 THR A C 1 ATOM 1884 O O . THR A 1 248 ? 3.089 11.428 15.272 1.00 48.58 ? 248 THR A O 1 ATOM 1885 C CB . THR A 1 248 ? 5.759 13.098 16.509 1.00 48.64 ? 248 THR A CB 1 ATOM 1886 O OG1 . THR A 1 248 ? 6.344 13.847 15.433 1.00 50.76 ? 248 THR A OG1 1 ATOM 1887 C CG2 . THR A 1 248 ? 6.197 11.629 16.440 1.00 48.75 ? 248 THR A CG2 1 ATOM 1888 N N . SER A 1 249 ? 4.028 13.074 14.034 1.00 48.62 ? 249 SER A N 1 ATOM 1889 C CA . SER A 1 249 ? 3.755 12.443 12.730 1.00 48.65 ? 249 SER A CA 1 ATOM 1890 C C . SER A 1 249 ? 4.542 11.131 12.542 1.00 47.37 ? 249 SER A C 1 ATOM 1891 O O . SER A 1 249 ? 4.088 10.204 11.856 1.00 46.63 ? 249 SER A O 1 ATOM 1892 C CB . SER A 1 249 ? 4.093 13.427 11.592 1.00 49.37 ? 249 SER A CB 1 ATOM 1893 O OG . SER A 1 249 ? 5.483 13.756 11.625 1.00 51.44 ? 249 SER A OG 1 ATOM 1894 N N . THR A 1 250 ? 5.712 11.070 13.178 1.00 46.22 ? 250 THR A N 1 ATOM 1895 C CA . THR A 1 250 ? 6.636 9.954 13.030 1.00 45.30 ? 250 THR A CA 1 ATOM 1896 C C . THR A 1 250 ? 6.346 8.775 13.970 1.00 44.28 ? 250 THR A C 1 ATOM 1897 O O . THR A 1 250 ? 7.195 7.902 14.157 1.00 43.69 ? 250 THR A O 1 ATOM 1898 C CB . THR A 1 250 ? 8.121 10.409 13.169 1.00 45.42 ? 250 THR A CB 1 ATOM 1899 O OG1 . THR A 1 250 ? 8.252 11.337 14.245 1.00 45.96 ? 250 THR A OG1 1 ATOM 1900 C CG2 . THR A 1 250 ? 8.624 11.077 11.899 1.00 47.33 ? 250 THR A CG2 1 ATOM 1901 N N . VAL A 1 251 ? 5.147 8.713 14.528 1.00 43.75 ? 251 VAL A N 1 ATOM 1902 C CA . VAL A 1 251 ? 4.860 7.656 15.492 1.00 43.89 ? 251 VAL A CA 1 ATOM 1903 C C . VAL A 1 251 ? 5.238 6.263 15.002 1.00 44.49 ? 251 VAL A C 1 ATOM 1904 O O . VAL A 1 251 ? 5.691 5.421 15.799 1.00 43.60 ? 251 VAL A O 1 ATOM 1905 C CB . VAL A 1 251 ? 3.424 7.743 16.069 1.00 44.18 ? 251 VAL A CB 1 ATOM 1906 C CG1 . VAL A 1 251 ? 2.421 8.304 15.060 1.00 44.59 ? 251 VAL A CG1 1 ATOM 1907 C CG2 . VAL A 1 251 ? 2.981 6.450 16.735 1.00 43.22 ? 251 VAL A CG2 1 ATOM 1908 N N . ASP A 1 252 ? 5.112 6.044 13.689 1.00 45.36 ? 252 ASP A N 1 ATOM 1909 C CA . ASP A 1 252 ? 5.311 4.715 13.084 1.00 45.86 ? 252 ASP A CA 1 ATOM 1910 C C . ASP A 1 252 ? 6.755 4.444 12.651 1.00 45.24 ? 252 ASP A C 1 ATOM 1911 O O . ASP A 1 252 ? 7.141 3.290 12.511 1.00 45.24 ? 252 ASP A O 1 ATOM 1912 C CB . ASP A 1 252 ? 4.349 4.518 11.900 1.00 46.36 ? 252 ASP A CB 1 ATOM 1913 C CG . ASP A 1 252 ? 2.885 4.377 12.342 1.00 49.65 ? 252 ASP A CG 1 ATOM 1914 O OD1 . ASP A 1 252 ? 2.613 3.559 13.236 1.00 50.42 ? 252 ASP A OD1 1 ATOM 1915 O OD2 . ASP A 1 252 ? 1.989 5.079 11.802 1.00 51.65 ? 252 ASP A OD2 1 ATOM 1916 N N . THR A 1 253 ? 7.542 5.502 12.463 1.00 44.91 ? 253 THR A N 1 ATOM 1917 C CA . THR A 1 253 ? 8.861 5.395 11.818 1.00 45.15 ? 253 THR A CA 1 ATOM 1918 C C . THR A 1 253 ? 10.017 5.620 12.800 1.00 44.74 ? 253 THR A C 1 ATOM 1919 O O . THR A 1 253 ? 11.046 4.973 12.699 1.00 44.94 ? 253 THR A O 1 ATOM 1920 C CB . THR A 1 253 ? 9.009 6.377 10.588 1.00 45.42 ? 253 THR A CB 1 ATOM 1921 O OG1 . THR A 1 253 ? 8.970 7.757 11.011 1.00 45.99 ? 253 THR A OG1 1 ATOM 1922 C CG2 . THR A 1 253 ? 7.902 6.167 9.572 1.00 46.38 ? 253 THR A CG2 1 ATOM 1923 N N . LYS A 1 254 ? 9.836 6.545 13.744 1.00 44.27 ? 254 LYS A N 1 ATOM 1924 C CA . LYS A 1 254 ? 10.914 6.970 14.676 1.00 43.75 ? 254 LYS A CA 1 ATOM 1925 C C . LYS A 1 254 ? 10.510 6.815 16.163 1.00 42.10 ? 254 LYS A C 1 ATOM 1926 O O . LYS A 1 254 ? 9.456 7.332 16.597 1.00 41.46 ? 254 LYS A O 1 ATOM 1927 C CB . LYS A 1 254 ? 11.302 8.434 14.391 1.00 43.64 ? 254 LYS A CB 1 ATOM 1928 C CG . LYS A 1 254 ? 12.761 8.753 14.599 1.00 47.68 ? 254 LYS A CG 1 ATOM 1929 C CD . LYS A 1 254 ? 13.123 10.261 14.388 1.00 54.41 ? 254 LYS A CD 1 ATOM 1930 C CE . LYS A 1 254 ? 12.873 10.782 12.908 1.00 57.41 ? 254 LYS A CE 1 ATOM 1931 N NZ . LYS A 1 254 ? 13.489 9.969 11.783 1.00 55.46 ? 254 LYS A NZ 1 ATOM 1932 N N . LEU A 1 255 ? 11.341 6.101 16.927 1.00 40.87 ? 255 LEU A N 1 ATOM 1933 C CA . LEU A 1 255 ? 11.254 6.105 18.414 1.00 39.63 ? 255 LEU A CA 1 ATOM 1934 C C . LEU A 1 255 ? 11.808 7.423 18.963 1.00 38.67 ? 255 LEU A C 1 ATOM 1935 O O . LEU A 1 255 ? 12.837 7.907 18.459 1.00 38.35 ? 255 LEU A O 1 ATOM 1936 C CB . LEU A 1 255 ? 12.034 4.935 18.992 1.00 39.48 ? 255 LEU A CB 1 ATOM 1937 C CG . LEU A 1 255 ? 11.632 4.416 20.368 1.00 39.32 ? 255 LEU A CG 1 ATOM 1938 C CD1 . LEU A 1 255 ? 10.142 4.126 20.476 1.00 34.51 ? 255 LEU A CD1 1 ATOM 1939 C CD2 . LEU A 1 255 ? 12.463 3.149 20.617 1.00 39.44 ? 255 LEU A CD2 1 ATOM 1940 N N . SER A 1 256 ? 11.133 8.035 19.938 1.00 37.28 ? 256 SER A N 1 ATOM 1941 C CA . SER A 1 256 ? 11.671 9.279 20.521 1.00 36.54 ? 256 SER A CA 1 ATOM 1942 C C . SER A 1 256 ? 13.151 9.143 20.927 1.00 35.45 ? 256 SER A C 1 ATOM 1943 O O . SER A 1 256 ? 13.607 8.046 21.276 1.00 35.52 ? 256 SER A O 1 ATOM 1944 C CB . SER A 1 256 ? 10.847 9.757 21.711 1.00 36.30 ? 256 SER A CB 1 ATOM 1945 O OG . SER A 1 256 ? 11.467 10.896 22.311 1.00 36.41 ? 256 SER A OG 1 ATOM 1946 N N . PRO A 1 257 ? 13.915 10.239 20.843 1.00 34.93 ? 257 PRO A N 1 ATOM 1947 C CA . PRO A 1 257 ? 15.304 10.222 21.361 1.00 34.11 ? 257 PRO A CA 1 ATOM 1948 C C . PRO A 1 257 ? 15.389 10.053 22.911 1.00 32.89 ? 257 PRO A C 1 ATOM 1949 O O . PRO A 1 257 ? 16.340 9.456 23.429 1.00 32.84 ? 257 PRO A O 1 ATOM 1950 C CB . PRO A 1 257 ? 15.871 11.590 20.931 1.00 34.51 ? 257 PRO A CB 1 ATOM 1951 C CG . PRO A 1 257 ? 14.858 12.183 19.926 1.00 34.84 ? 257 PRO A CG 1 ATOM 1952 C CD . PRO A 1 257 ? 13.539 11.546 20.251 1.00 35.33 ? 257 PRO A CD 1 ATOM 1953 N N . PHE A 1 258 ? 14.380 10.531 23.641 1.00 31.32 ? 258 PHE A N 1 ATOM 1954 C CA . PHE A 1 258 ? 14.297 10.246 25.063 1.00 29.73 ? 258 PHE A CA 1 ATOM 1955 C C . PHE A 1 258 ? 14.462 8.769 25.328 1.00 29.58 ? 258 PHE A C 1 ATOM 1956 O O . PHE A 1 258 ? 15.101 8.376 26.302 1.00 28.46 ? 258 PHE A O 1 ATOM 1957 C CB . PHE A 1 258 ? 13.001 10.763 25.665 1.00 28.11 ? 258 PHE A CB 1 ATOM 1958 C CG . PHE A 1 258 ? 12.932 12.255 25.748 1.00 27.76 ? 258 PHE A CG 1 ATOM 1959 C CD1 . PHE A 1 258 ? 13.544 12.949 26.784 1.00 26.25 ? 258 PHE A CD1 1 ATOM 1960 C CD2 . PHE A 1 258 ? 12.257 12.985 24.783 1.00 28.00 ? 258 PHE A CD2 1 ATOM 1961 C CE1 . PHE A 1 258 ? 13.449 14.325 26.884 1.00 27.50 ? 258 PHE A CE1 1 ATOM 1962 C CE2 . PHE A 1 258 ? 12.162 14.405 24.863 1.00 29.00 ? 258 PHE A CE2 1 ATOM 1963 C CZ . PHE A 1 258 ? 12.765 15.073 25.903 1.00 28.34 ? 258 PHE A CZ 1 ATOM 1964 N N . CYS A 1 259 ? 13.943 7.945 24.429 1.00 29.20 ? 259 CYS A N 1 ATOM 1965 C CA . CYS A 1 259 ? 13.949 6.487 24.673 1.00 30.30 ? 259 CYS A CA 1 ATOM 1966 C C . CYS A 1 259 ? 15.305 5.833 24.861 1.00 31.04 ? 259 CYS A C 1 ATOM 1967 O O . CYS A 1 259 ? 15.432 4.856 25.614 1.00 31.36 ? 259 CYS A O 1 ATOM 1968 C CB . CYS A 1 259 ? 13.157 5.750 23.597 1.00 29.35 ? 259 CYS A CB 1 ATOM 1969 S SG . CYS A 1 259 ? 11.532 6.464 23.521 1.00 28.53 ? 259 CYS A SG 1 ATOM 1970 N N . ASP A 1 260 ? 16.298 6.387 24.182 1.00 31.98 ? 260 ASP A N 1 ATOM 1971 C CA . ASP A 1 260 ? 17.600 5.770 24.079 1.00 32.85 ? 260 ASP A CA 1 ATOM 1972 C C . ASP A 1 260 ? 18.544 6.277 25.203 1.00 32.18 ? 260 ASP A C 1 ATOM 1973 O O . ASP A 1 260 ? 19.692 5.845 25.319 1.00 32.31 ? 260 ASP A O 1 ATOM 1974 C CB . ASP A 1 260 ? 18.158 6.054 22.680 1.00 34.01 ? 260 ASP A CB 1 ATOM 1975 C CG . ASP A 1 260 ? 19.296 5.117 22.298 1.00 39.12 ? 260 ASP A CG 1 ATOM 1976 O OD1 . ASP A 1 260 ? 19.322 3.921 22.753 1.00 42.84 ? 260 ASP A OD1 1 ATOM 1977 O OD2 . ASP A 1 260 ? 20.177 5.600 21.527 1.00 45.17 ? 260 ASP A OD2 1 ATOM 1978 N N . LEU A 1 261 ? 18.043 7.180 26.045 1.00 31.23 ? 261 LEU A N 1 ATOM 1979 C CA . LEU A 1 261 ? 18.769 7.579 27.266 1.00 29.90 ? 261 LEU A CA 1 ATOM 1980 C C . LEU A 1 261 ? 18.713 6.502 28.370 1.00 29.48 ? 261 LEU A C 1 ATOM 1981 O O . LEU A 1 261 ? 19.413 6.610 29.369 1.00 29.18 ? 261 LEU A O 1 ATOM 1982 C CB . LEU A 1 261 ? 18.243 8.906 27.787 1.00 29.10 ? 261 LEU A CB 1 ATOM 1983 C CG . LEU A 1 261 ? 18.115 10.068 26.794 1.00 27.80 ? 261 LEU A CG 1 ATOM 1984 C CD1 . LEU A 1 261 ? 17.502 11.217 27.519 1.00 27.47 ? 261 LEU A CD1 1 ATOM 1985 C CD2 . LEU A 1 261 ? 19.448 10.471 26.224 1.00 27.61 ? 261 LEU A CD2 1 ATOM 1986 N N . PHE A 1 262 ? 17.928 5.450 28.137 1.00 28.13 ? 262 PHE A N 1 ATOM 1987 C CA . PHE A 1 262 ? 17.658 4.408 29.118 1.00 27.34 ? 262 PHE A CA 1 ATOM 1988 C C . PHE A 1 262 ? 17.781 3.055 28.460 1.00 27.05 ? 262 PHE A C 1 ATOM 1989 O O . PHE A 1 262 ? 17.424 2.912 27.313 1.00 27.07 ? 262 PHE A O 1 ATOM 1990 C CB . PHE A 1 262 ? 16.232 4.600 29.658 1.00 25.69 ? 262 PHE A CB 1 ATOM 1991 C CG . PHE A 1 262 ? 15.969 6.003 30.078 1.00 24.79 ? 262 PHE A CG 1 ATOM 1992 C CD1 . PHE A 1 262 ? 16.402 6.453 31.325 1.00 23.89 ? 262 PHE A CD1 1 ATOM 1993 C CD2 . PHE A 1 262 ? 15.339 6.890 29.229 1.00 19.73 ? 262 PHE A CD2 1 ATOM 1994 C CE1 . PHE A 1 262 ? 16.206 7.757 31.719 1.00 21.00 ? 262 PHE A CE1 1 ATOM 1995 C CE2 . PHE A 1 262 ? 15.109 8.204 29.611 1.00 19.66 ? 262 PHE A CE2 1 ATOM 1996 C CZ . PHE A 1 262 ? 15.537 8.663 30.853 1.00 21.11 ? 262 PHE A CZ 1 ATOM 1997 N N . THR A 1 263 ? 18.295 2.075 29.179 1.00 27.39 ? 263 THR A N 1 ATOM 1998 C CA . THR A 1 263 ? 18.526 0.761 28.634 1.00 27.62 ? 263 THR A CA 1 ATOM 1999 C C . THR A 1 263 ? 17.270 -0.079 28.739 1.00 28.55 ? 263 THR A C 1 ATOM 2000 O O . THR A 1 263 ? 16.311 0.287 29.458 1.00 28.43 ? 263 THR A O 1 ATOM 2001 C CB . THR A 1 263 ? 19.590 0.019 29.452 1.00 28.38 ? 263 THR A CB 1 ATOM 2002 O OG1 . THR A 1 263 ? 19.055 -0.325 30.758 1.00 29.13 ? 263 THR A OG1 1 ATOM 2003 C CG2 . THR A 1 263 ? 20.933 0.876 29.562 1.00 28.75 ? 263 THR A CG2 1 ATOM 2004 N N . HIS A 1 264 ? 17.302 -1.231 28.064 1.00 28.47 ? 264 HIS A N 1 ATOM 2005 C CA . HIS A 1 264 ? 16.188 -2.135 28.028 1.00 29.55 ? 264 HIS A CA 1 ATOM 2006 C C . HIS A 1 264 ? 15.829 -2.564 29.458 1.00 30.33 ? 264 HIS A C 1 ATOM 2007 O O . HIS A 1 264 ? 14.639 -2.581 29.834 1.00 30.57 ? 264 HIS A O 1 ATOM 2008 C CB . HIS A 1 264 ? 16.498 -3.341 27.123 1.00 30.04 ? 264 HIS A CB 1 ATOM 2009 C CG . HIS A 1 264 ? 15.389 -4.349 27.034 1.00 29.30 ? 264 HIS A CG 1 ATOM 2010 N ND1 . HIS A 1 264 ? 14.203 -4.097 26.373 1.00 28.50 ? 264 HIS A ND1 1 ATOM 2011 C CD2 . HIS A 1 264 ? 15.294 -5.614 27.508 1.00 30.30 ? 264 HIS A CD2 1 ATOM 2012 C CE1 . HIS A 1 264 ? 13.416 -5.157 26.465 1.00 26.99 ? 264 HIS A CE1 1 ATOM 2013 N NE2 . HIS A 1 264 ? 14.055 -6.093 27.149 1.00 29.13 ? 264 HIS A NE2 1 ATOM 2014 N N . ASP A 1 265 ? 16.859 -2.876 30.255 1.00 29.78 ? 265 ASP A N 1 ATOM 2015 C CA . ASP A 1 265 ? 16.643 -3.311 31.622 1.00 29.79 ? 265 ASP A CA 1 ATOM 2016 C C . ASP A 1 265 ? 15.931 -2.242 32.481 1.00 27.59 ? 265 ASP A C 1 ATOM 2017 O O . ASP A 1 265 ? 15.130 -2.587 33.324 1.00 26.25 ? 265 ASP A O 1 ATOM 2018 C CB . ASP A 1 265 ? 17.966 -3.758 32.292 1.00 31.15 ? 265 ASP A CB 1 ATOM 2019 C CG . ASP A 1 265 ? 17.790 -4.000 33.785 1.00 36.33 ? 265 ASP A CG 1 ATOM 2020 O OD1 . ASP A 1 265 ? 18.304 -3.146 34.605 1.00 41.07 ? 265 ASP A OD1 1 ATOM 2021 O OD2 . ASP A 1 265 ? 17.079 -5.001 34.117 1.00 36.80 ? 265 ASP A OD2 1 ATOM 2022 N N . GLU A 1 266 ? 16.259 -0.972 32.257 1.00 26.26 ? 266 GLU A N 1 ATOM 2023 C CA . GLU A 1 266 ? 15.614 0.154 32.886 1.00 26.13 ? 266 GLU A CA 1 ATOM 2024 C C . GLU A 1 266 ? 14.175 0.318 32.413 1.00 26.28 ? 266 GLU A C 1 ATOM 2025 O O . GLU A 1 266 ? 13.253 0.622 33.234 1.00 26.05 ? 266 GLU A O 1 ATOM 2026 C CB . GLU A 1 266 ? 16.437 1.412 32.644 1.00 26.67 ? 266 GLU A CB 1 ATOM 2027 C CG . GLU A 1 266 ? 17.845 1.232 33.255 1.00 28.08 ? 266 GLU A CG 1 ATOM 2028 C CD . GLU A 1 266 ? 18.881 2.300 32.868 1.00 30.98 ? 266 GLU A CD 1 ATOM 2029 O OE1 . GLU A 1 266 ? 18.654 3.150 31.950 1.00 30.11 ? 266 GLU A OE1 1 ATOM 2030 O OE2 . GLU A 1 266 ? 19.970 2.266 33.481 1.00 33.10 ? 266 GLU A OE2 1 ATOM 2031 N N . TRP A 1 267 ? 13.933 0.042 31.130 1.00 25.26 ? 267 TRP A N 1 ATOM 2032 C CA . TRP A 1 267 ? 12.526 -0.023 30.684 1.00 24.27 ? 267 TRP A CA 1 ATOM 2033 C C . TRP A 1 267 ? 11.756 -1.147 31.391 1.00 24.67 ? 267 TRP A C 1 ATOM 2034 O O . TRP A 1 267 ? 10.543 -0.987 31.739 1.00 24.53 ? 267 TRP A O 1 ATOM 2035 C CB . TRP A 1 267 ? 12.409 -0.071 29.156 1.00 23.94 ? 267 TRP A CB 1 ATOM 2036 C CG . TRP A 1 267 ? 12.768 1.263 28.557 1.00 20.24 ? 267 TRP A CG 1 ATOM 2037 C CD1 . TRP A 1 267 ? 13.817 1.541 27.757 1.00 18.51 ? 267 TRP A CD1 1 ATOM 2038 C CD2 . TRP A 1 267 ? 12.089 2.497 28.769 1.00 18.12 ? 267 TRP A CD2 1 ATOM 2039 N NE1 . TRP A 1 267 ? 13.840 2.870 27.437 1.00 16.93 ? 267 TRP A NE1 1 ATOM 2040 C CE2 . TRP A 1 267 ? 12.781 3.478 28.052 1.00 16.49 ? 267 TRP A CE2 1 ATOM 2041 C CE3 . TRP A 1 267 ? 10.924 2.864 29.490 1.00 16.73 ? 267 TRP A CE3 1 ATOM 2042 C CZ2 . TRP A 1 267 ? 12.381 4.814 28.035 1.00 17.34 ? 267 TRP A CZ2 1 ATOM 2043 C CZ3 . TRP A 1 267 ? 10.526 4.181 29.478 1.00 18.83 ? 267 TRP A CZ3 1 ATOM 2044 C CH2 . TRP A 1 267 ? 11.252 5.151 28.756 1.00 17.44 ? 267 TRP A CH2 1 ATOM 2045 N N . ILE A 1 268 ? 12.431 -2.271 31.636 1.00 23.14 ? 268 ILE A N 1 ATOM 2046 C CA . ILE A 1 268 ? 11.765 -3.333 32.394 1.00 23.92 ? 268 ILE A CA 1 ATOM 2047 C C . ILE A 1 268 ? 11.308 -2.884 33.808 1.00 23.69 ? 268 ILE A C 1 ATOM 2048 O O . ILE A 1 268 ? 10.169 -3.113 34.232 1.00 24.13 ? 268 ILE A O 1 ATOM 2049 C CB . ILE A 1 268 ? 12.606 -4.605 32.433 1.00 24.09 ? 268 ILE A CB 1 ATOM 2050 C CG1 . ILE A 1 268 ? 12.600 -5.253 31.058 1.00 24.70 ? 268 ILE A CG1 1 ATOM 2051 C CG2 . ILE A 1 268 ? 12.034 -5.637 33.440 1.00 23.65 ? 268 ILE A CG2 1 ATOM 2052 C CD1 . ILE A 1 268 ? 13.712 -6.274 30.917 1.00 29.46 ? 268 ILE A CD1 1 ATOM 2053 N N . ASN A 1 269 ? 12.196 -2.217 34.516 1.00 23.04 ? 269 ASN A N 1 ATOM 2054 C CA . ASN A 1 269 ? 11.827 -1.613 35.793 1.00 22.48 ? 269 ASN A CA 1 ATOM 2055 C C . ASN A 1 269 ? 10.726 -0.579 35.639 1.00 21.52 ? 269 ASN A C 1 ATOM 2056 O O . ASN A 1 269 ? 9.738 -0.639 36.381 1.00 22.12 ? 269 ASN A O 1 ATOM 2057 C CB . ASN A 1 269 ? 13.095 -1.072 36.493 1.00 22.74 ? 269 ASN A CB 1 ATOM 2058 C CG . ASN A 1 269 ? 13.962 -2.214 37.049 1.00 25.11 ? 269 ASN A CG 1 ATOM 2059 O OD1 . ASN A 1 269 ? 13.575 -2.887 37.982 1.00 26.75 ? 269 ASN A OD1 1 ATOM 2060 N ND2 . ASN A 1 269 ? 15.098 -2.459 36.435 1.00 28.16 ? 269 ASN A ND2 1 ATOM 2061 N N . TYR A 1 270 ? 10.863 0.357 34.677 1.00 19.79 ? 270 TYR A N 1 ATOM 2062 C CA . TYR A 1 270 ? 9.801 1.325 34.403 1.00 19.13 ? 270 TYR A CA 1 ATOM 2063 C C . TYR A 1 270 ? 8.443 0.686 34.236 1.00 18.45 ? 270 TYR A C 1 ATOM 2064 O O . TYR A 1 270 ? 7.492 1.095 34.875 1.00 16.35 ? 270 TYR A O 1 ATOM 2065 C CB . TYR A 1 270 ? 10.091 2.109 33.148 1.00 19.74 ? 270 TYR A CB 1 ATOM 2066 C CG . TYR A 1 270 ? 9.129 3.249 32.839 1.00 19.21 ? 270 TYR A CG 1 ATOM 2067 C CD1 . TYR A 1 270 ? 9.273 4.503 33.436 1.00 18.26 ? 270 TYR A CD1 1 ATOM 2068 C CD2 . TYR A 1 270 ? 8.074 3.067 31.943 1.00 18.41 ? 270 TYR A CD2 1 ATOM 2069 C CE1 . TYR A 1 270 ? 8.381 5.567 33.128 1.00 17.17 ? 270 TYR A CE1 1 ATOM 2070 C CE2 . TYR A 1 270 ? 7.169 4.124 31.635 1.00 16.59 ? 270 TYR A CE2 1 ATOM 2071 C CZ . TYR A 1 270 ? 7.346 5.363 32.217 1.00 17.73 ? 270 TYR A CZ 1 ATOM 2072 O OH . TYR A 1 270 ? 6.460 6.382 31.894 1.00 17.50 ? 270 TYR A OH 1 ATOM 2073 N N . ASP A 1 271 ? 8.376 -0.343 33.385 1.00 19.08 ? 271 ASP A N 1 ATOM 2074 C CA . ASP A 1 271 ? 7.140 -1.016 33.095 1.00 19.50 ? 271 ASP A CA 1 ATOM 2075 C C . ASP A 1 271 ? 6.593 -1.580 34.385 1.00 20.29 ? 271 ASP A C 1 ATOM 2076 O O . ASP A 1 271 ? 5.373 -1.419 34.691 1.00 20.91 ? 271 ASP A O 1 ATOM 2077 C CB . ASP A 1 271 ? 7.358 -2.140 32.045 1.00 20.72 ? 271 ASP A CB 1 ATOM 2078 C CG . ASP A 1 271 ? 6.113 -2.948 31.787 1.00 20.05 ? 271 ASP A CG 1 ATOM 2079 O OD1 . ASP A 1 271 ? 5.166 -2.418 31.163 1.00 19.37 ? 271 ASP A OD1 1 ATOM 2080 O OD2 . ASP A 1 271 ? 6.065 -4.105 32.256 1.00 22.46 ? 271 ASP A OD2 1 ATOM 2081 N N . TYR A 1 272 ? 7.474 -2.226 35.161 1.00 19.75 ? 272 TYR A N 1 ATOM 2082 C CA . TYR A 1 272 ? 7.029 -2.849 36.396 1.00 18.87 ? 272 TYR A CA 1 ATOM 2083 C C . TYR A 1 272 ? 6.557 -1.792 37.359 1.00 19.47 ? 272 TYR A C 1 ATOM 2084 O O . TYR A 1 272 ? 5.486 -1.925 37.965 1.00 19.97 ? 272 TYR A O 1 ATOM 2085 C CB . TYR A 1 272 ? 8.119 -3.721 37.028 1.00 19.24 ? 272 TYR A CB 1 ATOM 2086 C CG . TYR A 1 272 ? 7.595 -4.598 38.166 1.00 21.08 ? 272 TYR A CG 1 ATOM 2087 C CD1 . TYR A 1 272 ? 6.747 -5.720 37.912 1.00 18.32 ? 272 TYR A CD1 1 ATOM 2088 C CD2 . TYR A 1 272 ? 7.916 -4.301 39.480 1.00 19.77 ? 272 TYR A CD2 1 ATOM 2089 C CE1 . TYR A 1 272 ? 6.244 -6.484 38.973 1.00 21.28 ? 272 TYR A CE1 1 ATOM 2090 C CE2 . TYR A 1 272 ? 7.447 -5.075 40.528 1.00 21.32 ? 272 TYR A CE2 1 ATOM 2091 C CZ . TYR A 1 272 ? 6.640 -6.160 40.290 1.00 21.27 ? 272 TYR A CZ 1 ATOM 2092 O OH . TYR A 1 272 ? 6.167 -6.875 41.372 1.00 20.33 ? 272 TYR A OH 1 ATOM 2093 N N . LEU A 1 273 ? 7.321 -0.710 37.477 1.00 19.26 ? 273 LEU A N 1 ATOM 2094 C CA . LEU A 1 273 ? 6.855 0.447 38.268 1.00 18.80 ? 273 LEU A CA 1 ATOM 2095 C C . LEU A 1 273 ? 5.431 0.747 37.877 1.00 18.84 ? 273 LEU A C 1 ATOM 2096 O O . LEU A 1 273 ? 4.575 0.981 38.752 1.00 17.58 ? 273 LEU A O 1 ATOM 2097 C CB . LEU A 1 273 ? 7.692 1.683 38.024 1.00 17.21 ? 273 LEU A CB 1 ATOM 2098 C CG . LEU A 1 273 ? 7.284 2.971 38.774 1.00 21.75 ? 273 LEU A CG 1 ATOM 2099 C CD1 . LEU A 1 273 ? 7.195 2.758 40.298 1.00 18.85 ? 273 LEU A CD1 1 ATOM 2100 C CD2 . LEU A 1 273 ? 8.257 4.114 38.497 1.00 21.13 ? 273 LEU A CD2 1 ATOM 2101 N N . GLN A 1 274 ? 5.173 0.783 36.551 1.00 19.13 ? 274 GLN A N 1 ATOM 2102 C CA . GLN A 1 274 ? 3.812 1.184 36.114 1.00 19.52 ? 274 GLN A CA 1 ATOM 2103 C C . GLN A 1 274 ? 2.765 0.157 36.561 1.00 19.08 ? 274 GLN A C 1 ATOM 2104 O O . GLN A 1 274 ? 1.731 0.566 37.064 1.00 20.23 ? 274 GLN A O 1 ATOM 2105 C CB . GLN A 1 274 ? 3.690 1.491 34.611 1.00 19.81 ? 274 GLN A CB 1 ATOM 2106 C CG . GLN A 1 274 ? 4.589 2.549 34.006 1.00 16.60 ? 274 GLN A CG 1 ATOM 2107 C CD . GLN A 1 274 ? 4.770 3.814 34.838 1.00 21.38 ? 274 GLN A CD 1 ATOM 2108 O OE1 . GLN A 1 274 ? 3.817 4.431 35.287 1.00 22.46 ? 274 GLN A OE1 1 ATOM 2109 N NE2 . GLN A 1 274 ? 6.044 4.247 34.993 1.00 24.75 ? 274 GLN A NE2 1 ATOM 2110 N N . SER A 1 275 ? 3.037 -1.150 36.424 1.00 18.54 ? 275 SER A N 1 ATOM 2111 C CA . SER A 1 275 ? 2.142 -2.161 36.986 1.00 17.47 ? 275 SER A CA 1 ATOM 2112 C C . SER A 1 275 ? 1.903 -1.992 38.510 1.00 18.15 ? 275 SER A C 1 ATOM 2113 O O . SER A 1 275 ? 0.775 -2.151 38.983 1.00 16.20 ? 275 SER A O 1 ATOM 2114 C CB . SER A 1 275 ? 2.684 -3.557 36.717 1.00 17.85 ? 275 SER A CB 1 ATOM 2115 O OG . SER A 1 275 ? 2.786 -3.879 35.352 1.00 16.14 ? 275 SER A OG 1 ATOM 2116 N N . LEU A 1 276 ? 2.966 -1.660 39.266 1.00 18.50 ? 276 LEU A N 1 ATOM 2117 C CA . LEU A 1 276 ? 2.825 -1.369 40.719 1.00 19.97 ? 276 LEU A CA 1 ATOM 2118 C C . LEU A 1 276 ? 1.881 -0.232 41.051 1.00 20.52 ? 276 LEU A C 1 ATOM 2119 O O . LEU A 1 276 ? 0.957 -0.415 41.883 1.00 21.12 ? 276 LEU A O 1 ATOM 2120 C CB . LEU A 1 276 ? 4.147 -1.085 41.409 1.00 20.03 ? 276 LEU A CB 1 ATOM 2121 C CG . LEU A 1 276 ? 5.093 -2.281 41.580 1.00 21.17 ? 276 LEU A CG 1 ATOM 2122 C CD1 . LEU A 1 276 ? 6.391 -1.677 42.037 1.00 18.51 ? 276 LEU A CD1 1 ATOM 2123 C CD2 . LEU A 1 276 ? 4.607 -3.409 42.536 1.00 20.20 ? 276 LEU A CD2 1 ATOM 2124 N N . LYS A 1 277 ? 2.060 0.906 40.381 1.00 20.01 ? 277 LYS A N 1 ATOM 2125 C CA . LYS A 1 277 ? 1.172 2.022 40.597 1.00 20.48 ? 277 LYS A CA 1 ATOM 2126 C C . LYS A 1 277 ? -0.302 1.609 40.405 1.00 20.64 ? 277 LYS A C 1 ATOM 2127 O O . LYS A 1 277 ? -1.198 1.988 41.191 1.00 19.92 ? 277 LYS A O 1 ATOM 2128 C CB . LYS A 1 277 ? 1.480 3.128 39.607 1.00 21.01 ? 277 LYS A CB 1 ATOM 2129 C CG . LYS A 1 277 ? 2.846 3.791 39.670 1.00 22.35 ? 277 LYS A CG 1 ATOM 2130 C CD . LYS A 1 277 ? 2.664 5.227 39.129 1.00 27.48 ? 277 LYS A CD 1 ATOM 2131 C CE . LYS A 1 277 ? 3.685 5.532 38.063 1.00 32.69 ? 277 LYS A CE 1 ATOM 2132 N NZ . LYS A 1 277 ? 3.535 6.877 37.355 1.00 33.84 ? 277 LYS A NZ 1 ATOM 2133 N N . LYS A 1 278 ? -0.561 0.843 39.342 1.00 19.94 ? 278 LYS A N 1 ATOM 2134 C CA . LYS A 1 278 ? -1.932 0.467 39.064 1.00 19.51 ? 278 LYS A CA 1 ATOM 2135 C C . LYS A 1 278 ? -2.388 -0.602 40.046 1.00 19.26 ? 278 LYS A C 1 ATOM 2136 O O . LYS A 1 278 ? -3.468 -0.459 40.638 1.00 20.09 ? 278 LYS A O 1 ATOM 2137 C CB . LYS A 1 278 ? -2.095 0.055 37.593 1.00 18.53 ? 278 LYS A CB 1 ATOM 2138 C CG . LYS A 1 278 ? -1.871 1.230 36.629 1.00 19.70 ? 278 LYS A CG 1 ATOM 2139 C CD . LYS A 1 278 ? -2.546 2.515 37.099 1.00 15.06 ? 278 LYS A CD 1 ATOM 2140 C CE . LYS A 1 278 ? -2.414 3.574 36.025 1.00 20.74 ? 278 LYS A CE 1 ATOM 2141 N NZ . LYS A 1 278 ? -2.887 4.899 36.450 1.00 16.02 ? 278 LYS A NZ 1 ATOM 2142 N N . TYR A 1 279 ? -1.608 -1.664 40.213 1.00 17.37 ? 279 TYR A N 1 ATOM 2143 C CA . TYR A 1 279 ? -1.964 -2.720 41.186 1.00 18.04 ? 279 TYR A CA 1 ATOM 2144 C C . TYR A 1 279 ? -2.339 -2.262 42.601 1.00 18.18 ? 279 TYR A C 1 ATOM 2145 O O . TYR A 1 279 ? -3.408 -2.655 43.123 1.00 17.74 ? 279 TYR A O 1 ATOM 2146 C CB . TYR A 1 279 ? -0.851 -3.741 41.315 1.00 18.49 ? 279 TYR A CB 1 ATOM 2147 C CG . TYR A 1 279 ? -1.303 -4.940 42.104 1.00 19.95 ? 279 TYR A CG 1 ATOM 2148 C CD1 . TYR A 1 279 ? -2.056 -5.956 41.494 1.00 17.59 ? 279 TYR A CD1 1 ATOM 2149 C CD2 . TYR A 1 279 ? -0.999 -5.062 43.470 1.00 19.42 ? 279 TYR A CD2 1 ATOM 2150 C CE1 . TYR A 1 279 ? -2.512 -7.053 42.225 1.00 18.52 ? 279 TYR A CE1 1 ATOM 2151 C CE2 . TYR A 1 279 ? -1.439 -6.166 44.199 1.00 21.80 ? 279 TYR A CE2 1 ATOM 2152 C CZ . TYR A 1 279 ? -2.174 -7.165 43.598 1.00 22.46 ? 279 TYR A CZ 1 ATOM 2153 O OH . TYR A 1 279 ? -2.573 -8.262 44.363 1.00 20.67 ? 279 TYR A OH 1 ATOM 2154 N N . TYR A 1 280 ? -1.468 -1.426 43.212 1.00 18.81 ? 280 TYR A N 1 ATOM 2155 C CA . TYR A 1 280 ? -1.695 -0.841 44.566 1.00 17.74 ? 280 TYR A CA 1 ATOM 2156 C C . TYR A 1 280 ? -2.532 0.404 44.561 1.00 18.30 ? 280 TYR A C 1 ATOM 2157 O O . TYR A 1 280 ? -3.017 0.809 45.634 1.00 18.81 ? 280 TYR A O 1 ATOM 2158 C CB . TYR A 1 280 ? -0.353 -0.600 45.327 1.00 16.55 ? 280 TYR A CB 1 ATOM 2159 C CG . TYR A 1 280 ? 0.314 -1.922 45.650 1.00 17.03 ? 280 TYR A CG 1 ATOM 2160 C CD1 . TYR A 1 280 ? -0.134 -2.693 46.708 1.00 16.58 ? 280 TYR A CD1 1 ATOM 2161 C CD2 . TYR A 1 280 ? 1.356 -2.424 44.871 1.00 14.83 ? 280 TYR A CD2 1 ATOM 2162 C CE1 . TYR A 1 280 ? 0.443 -3.956 46.988 1.00 18.54 ? 280 TYR A CE1 1 ATOM 2163 C CE2 . TYR A 1 280 ? 1.924 -3.715 45.131 1.00 14.62 ? 280 TYR A CE2 1 ATOM 2164 C CZ . TYR A 1 280 ? 1.458 -4.458 46.194 1.00 15.87 ? 280 TYR A CZ 1 ATOM 2165 O OH . TYR A 1 280 ? 1.947 -5.738 46.455 1.00 14.35 ? 280 TYR A OH 1 ATOM 2166 N N . GLY A 1 281 ? -2.685 1.068 43.403 1.00 17.62 ? 281 GLY A N 1 ATOM 2167 C CA . GLY A 1 281 ? -3.556 2.233 43.358 1.00 17.10 ? 281 GLY A CA 1 ATOM 2168 C C . GLY A 1 281 ? -5.042 1.867 43.228 1.00 18.33 ? 281 GLY A C 1 ATOM 2169 O O . GLY A 1 281 ? -5.890 2.410 43.928 1.00 18.05 ? 281 GLY A O 1 ATOM 2170 N N . HIS A 1 282 ? -5.357 0.925 42.325 1.00 18.91 ? 282 HIS A N 1 ATOM 2171 C CA . HIS A 1 282 ? -6.715 0.673 41.895 1.00 19.17 ? 282 HIS A CA 1 ATOM 2172 C C . HIS A 1 282 ? -7.082 -0.789 41.809 1.00 18.42 ? 282 HIS A C 1 ATOM 2173 O O . HIS A 1 282 ? -8.276 -1.146 41.792 1.00 19.28 ? 282 HIS A O 1 ATOM 2174 C CB . HIS A 1 282 ? -6.963 1.389 40.558 1.00 20.36 ? 282 HIS A CB 1 ATOM 2175 C CG . HIS A 1 282 ? -6.916 2.877 40.671 1.00 20.66 ? 282 HIS A CG 1 ATOM 2176 N ND1 . HIS A 1 282 ? -8.039 3.642 40.924 1.00 21.69 ? 282 HIS A ND1 1 ATOM 2177 C CD2 . HIS A 1 282 ? -5.870 3.735 40.602 1.00 22.45 ? 282 HIS A CD2 1 ATOM 2178 C CE1 . HIS A 1 282 ? -7.681 4.905 41.024 1.00 23.18 ? 282 HIS A CE1 1 ATOM 2179 N NE2 . HIS A 1 282 ? -6.374 4.988 40.831 1.00 23.77 ? 282 HIS A NE2 1 ATOM 2180 N N . GLY A 1 283 ? -6.082 -1.638 41.798 1.00 18.12 ? 283 GLY A N 1 ATOM 2181 C CA . GLY A 1 283 ? -6.302 -3.097 41.789 1.00 18.06 ? 283 GLY A CA 1 ATOM 2182 C C . GLY A 1 283 ? -6.321 -3.776 43.151 1.00 17.85 ? 283 GLY A C 1 ATOM 2183 O O . GLY A 1 283 ? -6.381 -3.119 44.176 1.00 19.08 ? 283 GLY A O 1 ATOM 2184 N N . ALA A 1 284 ? -6.300 -5.104 43.157 1.00 18.35 ? 284 ALA A N 1 ATOM 2185 C CA . ALA A 1 284 ? -6.343 -5.905 44.404 1.00 19.26 ? 284 ALA A CA 1 ATOM 2186 C C . ALA A 1 284 ? -5.335 -5.524 45.504 1.00 19.74 ? 284 ALA A C 1 ATOM 2187 O O . ALA A 1 284 ? -5.605 -5.786 46.679 1.00 21.17 ? 284 ALA A O 1 ATOM 2188 C CB . ALA A 1 284 ? -6.267 -7.388 44.121 1.00 18.13 ? 284 ALA A CB 1 ATOM 2189 N N . GLY A 1 285 ? -4.218 -4.890 45.137 1.00 19.19 ? 285 GLY A N 1 ATOM 2190 C CA . GLY A 1 285 ? -3.291 -4.386 46.106 1.00 18.88 ? 285 GLY A CA 1 ATOM 2191 C C . GLY A 1 285 ? -3.842 -3.289 46.998 1.00 20.47 ? 285 GLY A C 1 ATOM 2192 O O . GLY A 1 285 ? -3.274 -3.059 48.093 1.00 19.99 ? 285 GLY A O 1 ATOM 2193 N N . ASN A 1 286 ? -4.875 -2.555 46.533 1.00 18.39 ? 286 ASN A N 1 ATOM 2194 C CA . ASN A 1 286 ? -5.360 -1.510 47.335 1.00 19.15 ? 286 ASN A CA 1 ATOM 2195 C C . ASN A 1 286 ? -6.611 -1.996 48.033 1.00 20.06 ? 286 ASN A C 1 ATOM 2196 O O . ASN A 1 286 ? -7.476 -2.609 47.414 1.00 19.68 ? 286 ASN A O 1 ATOM 2197 C CB . ASN A 1 286 ? -5.640 -0.277 46.513 1.00 19.41 ? 286 ASN A CB 1 ATOM 2198 C CG . ASN A 1 286 ? -6.092 0.841 47.350 1.00 21.36 ? 286 ASN A CG 1 ATOM 2199 O OD1 . ASN A 1 286 ? -7.214 0.811 47.924 1.00 22.69 ? 286 ASN A OD1 1 ATOM 2200 N ND2 . ASN A 1 286 ? -5.238 1.858 47.467 1.00 18.74 ? 286 ASN A ND2 1 ATOM 2201 N N . PRO A 1 287 ? -6.717 -1.774 49.339 1.00 21.30 ? 287 PRO A N 1 ATOM 2202 C CA . PRO A 1 287 ? -7.852 -2.446 50.009 1.00 21.42 ? 287 PRO A CA 1 ATOM 2203 C C . PRO A 1 287 ? -9.240 -2.045 49.475 1.00 21.20 ? 287 PRO A C 1 ATOM 2204 O O . PRO A 1 287 ? -10.125 -2.848 49.525 1.00 20.08 ? 287 PRO A O 1 ATOM 2205 C CB . PRO A 1 287 ? -7.712 -2.034 51.456 1.00 21.32 ? 287 PRO A CB 1 ATOM 2206 C CG . PRO A 1 287 ? -6.659 -0.924 51.471 1.00 23.74 ? 287 PRO A CG 1 ATOM 2207 C CD . PRO A 1 287 ? -5.765 -1.206 50.309 1.00 22.06 ? 287 PRO A CD 1 ATOM 2208 N N . LEU A 1 288 ? -9.398 -0.837 48.937 1.00 20.98 ? 288 LEU A N 1 ATOM 2209 C CA . LEU A 1 288 ? -10.682 -0.434 48.389 1.00 20.93 ? 288 LEU A CA 1 ATOM 2210 C C . LEU A 1 288 ? -10.686 -0.316 46.831 1.00 20.58 ? 288 LEU A C 1 ATOM 2211 O O . LEU A 1 288 ? -11.622 0.281 46.239 1.00 20.62 ? 288 LEU A O 1 ATOM 2212 C CB . LEU A 1 288 ? -11.093 0.896 49.039 1.00 21.12 ? 288 LEU A CB 1 ATOM 2213 C CG . LEU A 1 288 ? -11.416 0.887 50.535 1.00 22.48 ? 288 LEU A CG 1 ATOM 2214 C CD1 . LEU A 1 288 ? -11.716 2.288 50.995 1.00 22.28 ? 288 LEU A CD1 1 ATOM 2215 C CD2 . LEU A 1 288 ? -12.608 -0.009 50.833 1.00 25.92 ? 288 LEU A CD2 1 ATOM 2216 N N . GLY A 1 289 ? -9.647 -0.869 46.195 1.00 18.92 ? 289 GLY A N 1 ATOM 2217 C CA . GLY A 1 289 ? -9.451 -0.791 44.756 1.00 18.49 ? 289 GLY A CA 1 ATOM 2218 C C . GLY A 1 289 ? -10.519 -1.596 44.007 1.00 17.83 ? 289 GLY A C 1 ATOM 2219 O O . GLY A 1 289 ? -11.320 -1.010 43.263 1.00 17.80 ? 289 GLY A O 1 ATOM 2220 N N . PRO A 1 290 ? -10.585 -2.914 44.249 1.00 16.85 ? 290 PRO A N 1 ATOM 2221 C CA . PRO A 1 290 ? -11.563 -3.744 43.518 1.00 17.18 ? 290 PRO A CA 1 ATOM 2222 C C . PRO A 1 290 ? -12.978 -3.314 43.831 1.00 18.19 ? 290 PRO A C 1 ATOM 2223 O O . PRO A 1 290 ? -13.902 -3.545 43.010 1.00 18.82 ? 290 PRO A O 1 ATOM 2224 C CB . PRO A 1 290 ? -11.284 -5.186 44.041 1.00 16.90 ? 290 PRO A CB 1 ATOM 2225 C CG . PRO A 1 290 ? -9.868 -5.118 44.536 1.00 15.51 ? 290 PRO A CG 1 ATOM 2226 C CD . PRO A 1 290 ? -9.777 -3.741 45.175 1.00 16.42 ? 290 PRO A CD 1 ATOM 2227 N N . THR A 1 291 ? -13.124 -2.613 44.968 1.00 18.26 ? 291 THR A N 1 ATOM 2228 C CA . THR A 1 291 ? -14.408 -2.110 45.405 1.00 18.60 ? 291 THR A CA 1 ATOM 2229 C C . THR A 1 291 ? -14.843 -0.955 44.483 1.00 18.69 ? 291 THR A C 1 ATOM 2230 O O . THR A 1 291 ? -16.045 -0.682 44.350 1.00 19.25 ? 291 THR A O 1 ATOM 2231 C CB . THR A 1 291 ? -14.380 -1.715 46.914 1.00 18.38 ? 291 THR A CB 1 ATOM 2232 O OG1 . THR A 1 291 ? -14.546 -2.909 47.720 1.00 18.42 ? 291 THR A OG1 1 ATOM 2233 C CG2 . THR A 1 291 ? -15.447 -0.689 47.255 1.00 16.33 ? 291 THR A CG2 1 ATOM 2234 N N . GLN A 1 292 ? -13.876 -0.320 43.814 1.00 18.09 ? 292 GLN A N 1 ATOM 2235 C CA . GLN A 1 292 ? -14.196 0.758 42.871 1.00 18.39 ? 292 GLN A CA 1 ATOM 2236 C C . GLN A 1 292 ? -14.872 0.189 41.592 1.00 18.55 ? 292 GLN A C 1 ATOM 2237 O O . GLN A 1 292 ? -15.528 0.928 40.849 1.00 19.28 ? 292 GLN A O 1 ATOM 2238 C CB . GLN A 1 292 ? -12.946 1.576 42.515 1.00 19.01 ? 292 GLN A CB 1 ATOM 2239 C CG . GLN A 1 292 ? -12.283 2.358 43.719 1.00 17.86 ? 292 GLN A CG 1 ATOM 2240 C CD . GLN A 1 292 ? -13.324 3.020 44.676 1.00 19.32 ? 292 GLN A CD 1 ATOM 2241 O OE1 . GLN A 1 292 ? -13.956 4.043 44.331 1.00 22.02 ? 292 GLN A OE1 1 ATOM 2242 N NE2 . GLN A 1 292 ? -13.491 2.446 45.879 1.00 13.63 ? 292 GLN A NE2 1 ATOM 2243 N N . GLY A 1 293 ? -14.757 -1.135 41.384 1.00 18.75 ? 293 GLY A N 1 ATOM 2244 C CA . GLY A 1 293 ? -15.260 -1.792 40.194 1.00 17.58 ? 293 GLY A CA 1 ATOM 2245 C C . GLY A 1 293 ? -16.616 -2.437 40.371 1.00 17.95 ? 293 GLY A C 1 ATOM 2246 O O . GLY A 1 293 ? -17.133 -3.051 39.429 1.00 17.76 ? 293 GLY A O 1 ATOM 2247 N N . VAL A 1 294 ? -17.193 -2.374 41.570 1.00 18.09 ? 294 VAL A N 1 ATOM 2248 C CA . VAL A 1 294 ? -18.381 -3.238 41.789 1.00 18.94 ? 294 VAL A CA 1 ATOM 2249 C C . VAL A 1 294 ? -19.655 -2.670 41.138 1.00 17.57 ? 294 VAL A C 1 ATOM 2250 O O . VAL A 1 294 ? -20.507 -3.411 40.710 1.00 19.56 ? 294 VAL A O 1 ATOM 2251 C CB . VAL A 1 294 ? -18.593 -3.781 43.270 1.00 19.26 ? 294 VAL A CB 1 ATOM 2252 C CG1 . VAL A 1 294 ? -17.267 -3.896 44.087 1.00 20.83 ? 294 VAL A CG1 1 ATOM 2253 C CG2 . VAL A 1 294 ? -19.732 -3.108 43.993 1.00 20.42 ? 294 VAL A CG2 1 ATOM 2254 N N . GLY A 1 295 ? -19.727 -1.362 41.001 1.00 16.95 ? 295 GLY A N 1 ATOM 2255 C CA . GLY A 1 295 ? -20.792 -0.757 40.256 1.00 16.64 ? 295 GLY A CA 1 ATOM 2256 C C . GLY A 1 295 ? -20.922 -1.296 38.852 1.00 15.73 ? 295 GLY A C 1 ATOM 2257 O O . GLY A 1 295 ? -21.985 -1.678 38.452 1.00 16.76 ? 295 GLY A O 1 ATOM 2258 N N . TYR A 1 296 ? -19.825 -1.305 38.111 1.00 14.90 ? 296 TYR A N 1 ATOM 2259 C CA . TYR A 1 296 ? -19.811 -1.703 36.788 1.00 15.10 ? 296 TYR A CA 1 ATOM 2260 C C . TYR A 1 296 ? -20.065 -3.173 36.740 1.00 16.44 ? 296 TYR A C 1 ATOM 2261 O O . TYR A 1 296 ? -20.824 -3.642 35.888 1.00 17.85 ? 296 TYR A O 1 ATOM 2262 C CB . TYR A 1 296 ? -18.451 -1.338 36.143 1.00 17.10 ? 296 TYR A CB 1 ATOM 2263 C CG . TYR A 1 296 ? -18.482 -1.466 34.645 1.00 17.19 ? 296 TYR A CG 1 ATOM 2264 C CD1 . TYR A 1 296 ? -18.893 -0.411 33.863 1.00 19.46 ? 296 TYR A CD1 1 ATOM 2265 C CD2 . TYR A 1 296 ? -18.178 -2.684 34.030 1.00 18.18 ? 296 TYR A CD2 1 ATOM 2266 C CE1 . TYR A 1 296 ? -18.924 -0.525 32.487 1.00 21.42 ? 296 TYR A CE1 1 ATOM 2267 C CE2 . TYR A 1 296 ? -18.204 -2.821 32.658 1.00 20.12 ? 296 TYR A CE2 1 ATOM 2268 C CZ . TYR A 1 296 ? -18.599 -1.745 31.880 1.00 20.68 ? 296 TYR A CZ 1 ATOM 2269 O OH . TYR A 1 296 ? -18.661 -1.864 30.495 1.00 22.04 ? 296 TYR A OH 1 ATOM 2270 N N . ALA A 1 297 ? -19.469 -3.930 37.662 1.00 16.06 ? 297 ALA A N 1 ATOM 2271 C CA . ALA A 1 297 ? -19.679 -5.352 37.714 1.00 14.88 ? 297 ALA A CA 1 ATOM 2272 C C . ALA A 1 297 ? -21.158 -5.668 37.924 1.00 15.47 ? 297 ALA A C 1 ATOM 2273 O O . ALA A 1 297 ? -21.703 -6.581 37.267 1.00 14.88 ? 297 ALA A O 1 ATOM 2274 C CB . ALA A 1 297 ? -18.814 -5.969 38.830 1.00 15.06 ? 297 ALA A CB 1 ATOM 2275 N N . ASN A 1 298 ? -21.828 -4.916 38.789 1.00 14.70 ? 298 ASN A N 1 ATOM 2276 C CA . ASN A 1 298 ? -23.257 -5.138 38.925 1.00 17.32 ? 298 ASN A CA 1 ATOM 2277 C C . ASN A 1 298 ? -24.084 -4.744 37.696 1.00 18.71 ? 298 ASN A C 1 ATOM 2278 O O . ASN A 1 298 ? -25.054 -5.465 37.365 1.00 19.95 ? 298 ASN A O 1 ATOM 2279 C CB . ASN A 1 298 ? -23.814 -4.475 40.187 1.00 17.39 ? 298 ASN A CB 1 ATOM 2280 C CG . ASN A 1 298 ? -23.402 -5.236 41.429 1.00 18.09 ? 298 ASN A CG 1 ATOM 2281 O OD1 . ASN A 1 298 ? -23.311 -6.473 41.413 1.00 13.59 ? 298 ASN A OD1 1 ATOM 2282 N ND2 . ASN A 1 298 ? -23.073 -4.503 42.476 1.00 17.23 ? 298 ASN A ND2 1 ATOM 2283 N N . GLU A 1 299 ? -23.687 -3.650 37.014 1.00 17.46 ? 299 GLU A N 1 ATOM 2284 C CA . GLU A 1 299 ? -24.263 -3.327 35.692 1.00 16.60 ? 299 GLU A CA 1 ATOM 2285 C C . GLU A 1 299 ? -24.039 -4.447 34.672 1.00 16.74 ? 299 GLU A C 1 ATOM 2286 O O . GLU A 1 299 ? -24.961 -4.854 33.969 1.00 17.38 ? 299 GLU A O 1 ATOM 2287 C CB . GLU A 1 299 ? -23.696 -1.997 35.173 1.00 16.65 ? 299 GLU A CB 1 ATOM 2288 C CG . GLU A 1 299 ? -24.236 -0.841 35.986 1.00 13.53 ? 299 GLU A CG 1 ATOM 2289 C CD . GLU A 1 299 ? -23.761 0.475 35.493 1.00 17.23 ? 299 GLU A CD 1 ATOM 2290 O OE1 . GLU A 1 299 ? -22.634 0.541 34.949 1.00 12.91 ? 299 GLU A OE1 1 ATOM 2291 O OE2 . GLU A 1 299 ? -24.535 1.458 35.615 1.00 18.98 ? 299 GLU A OE2 1 ATOM 2292 N N . LEU A 1 300 ? -22.842 -5.004 34.648 1.00 16.43 ? 300 LEU A N 1 ATOM 2293 C CA . LEU A 1 300 ? -22.569 -6.113 33.764 1.00 17.72 ? 300 LEU A CA 1 ATOM 2294 C C . LEU A 1 300 ? -23.453 -7.313 34.041 1.00 18.12 ? 300 LEU A C 1 ATOM 2295 O O . LEU A 1 300 ? -23.927 -7.948 33.131 1.00 19.90 ? 300 LEU A O 1 ATOM 2296 C CB . LEU A 1 300 ? -21.118 -6.548 33.813 1.00 16.35 ? 300 LEU A CB 1 ATOM 2297 C CG . LEU A 1 300 ? -20.913 -7.772 32.920 1.00 17.39 ? 300 LEU A CG 1 ATOM 2298 C CD1 . LEU A 1 300 ? -21.204 -7.410 31.472 1.00 16.91 ? 300 LEU A CD1 1 ATOM 2299 C CD2 . LEU A 1 300 ? -19.407 -8.305 33.055 1.00 15.47 ? 300 LEU A CD2 1 ATOM 2300 N N . ILE A 1 301 ? -23.690 -7.621 35.295 1.00 18.37 ? 301 ILE A N 1 ATOM 2301 C CA . ILE A 1 301 ? -24.522 -8.739 35.619 1.00 18.61 ? 301 ILE A CA 1 ATOM 2302 C C . ILE A 1 301 ? -25.998 -8.508 35.169 1.00 18.62 ? 301 ILE A C 1 ATOM 2303 O O . ILE A 1 301 ? -26.711 -9.453 34.762 1.00 18.82 ? 301 ILE A O 1 ATOM 2304 C CB . ILE A 1 301 ? -24.414 -9.013 37.156 1.00 18.51 ? 301 ILE A CB 1 ATOM 2305 C CG1 . ILE A 1 301 ? -23.114 -9.725 37.536 1.00 19.24 ? 301 ILE A CG1 1 ATOM 2306 C CG2 . ILE A 1 301 ? -25.663 -9.660 37.734 1.00 17.92 ? 301 ILE A CG2 1 ATOM 2307 C CD1 . ILE A 1 301 ? -22.897 -9.543 39.056 1.00 17.54 ? 301 ILE A CD1 1 ATOM 2308 N N . ALA A 1 302 ? -26.464 -7.270 35.276 1.00 18.61 ? 302 ALA A N 1 ATOM 2309 C CA . ALA A 1 302 ? -27.852 -6.943 34.870 1.00 18.94 ? 302 ALA A CA 1 ATOM 2310 C C . ALA A 1 302 ? -27.977 -7.226 33.385 1.00 19.74 ? 302 ALA A C 1 ATOM 2311 O O . ALA A 1 302 ? -28.934 -7.824 32.956 1.00 20.12 ? 302 ALA A O 1 ATOM 2312 C CB . ALA A 1 302 ? -28.148 -5.494 35.123 1.00 18.29 ? 302 ALA A CB 1 ATOM 2313 N N . ARG A 1 303 ? -26.954 -6.806 32.624 1.00 20.30 ? 303 ARG A N 1 ATOM 2314 C CA . ARG A 1 303 ? -26.880 -7.016 31.191 1.00 19.94 ? 303 ARG A CA 1 ATOM 2315 C C . ARG A 1 303 ? -26.824 -8.501 30.828 1.00 20.45 ? 303 ARG A C 1 ATOM 2316 O O . ARG A 1 303 ? -27.539 -8.955 29.938 1.00 20.01 ? 303 ARG A O 1 ATOM 2317 C CB . ARG A 1 303 ? -25.729 -6.230 30.575 1.00 18.84 ? 303 ARG A CB 1 ATOM 2318 C CG . ARG A 1 303 ? -26.027 -4.753 30.513 1.00 18.16 ? 303 ARG A CG 1 ATOM 2319 C CD . ARG A 1 303 ? -24.817 -3.943 30.091 1.00 17.08 ? 303 ARG A CD 1 ATOM 2320 N NE . ARG A 1 303 ? -25.232 -2.536 29.924 1.00 18.00 ? 303 ARG A NE 1 ATOM 2321 C CZ . ARG A 1 303 ? -24.390 -1.521 29.718 1.00 16.97 ? 303 ARG A CZ 1 ATOM 2322 N NH1 . ARG A 1 303 ? -23.070 -1.760 29.617 1.00 14.06 ? 303 ARG A NH1 1 ATOM 2323 N NH2 . ARG A 1 303 ? -24.864 -0.278 29.558 1.00 12.89 ? 303 ARG A NH2 1 ATOM 2324 N N . LEU A 1 304 ? -26.006 -9.263 31.537 1.00 21.39 ? 304 LEU A N 1 ATOM 2325 C CA . LEU A 1 304 ? -25.889 -10.668 31.245 1.00 21.05 ? 304 LEU A CA 1 ATOM 2326 C C . LEU A 1 304 ? -27.169 -11.376 31.604 1.00 22.25 ? 304 LEU A C 1 ATOM 2327 O O . LEU A 1 304 ? -27.573 -12.307 30.900 1.00 23.26 ? 304 LEU A O 1 ATOM 2328 C CB . LEU A 1 304 ? -24.717 -11.274 31.966 1.00 21.13 ? 304 LEU A CB 1 ATOM 2329 C CG . LEU A 1 304 ? -23.304 -10.746 31.674 1.00 20.58 ? 304 LEU A CG 1 ATOM 2330 C CD1 . LEU A 1 304 ? -22.374 -11.645 32.464 1.00 16.33 ? 304 LEU A CD1 1 ATOM 2331 C CD2 . LEU A 1 304 ? -22.908 -10.805 30.238 1.00 20.68 ? 304 LEU A CD2 1 ATOM 2332 N N . THR A 1 305 ? -27.820 -10.948 32.677 1.00 21.89 ? 305 THR A N 1 ATOM 2333 C CA . THR A 1 305 ? -29.071 -11.636 33.090 1.00 23.08 ? 305 THR A CA 1 ATOM 2334 C C . THR A 1 305 ? -30.370 -10.969 32.689 1.00 22.76 ? 305 THR A C 1 ATOM 2335 O O . THR A 1 305 ? -31.422 -11.421 33.140 1.00 23.25 ? 305 THR A O 1 ATOM 2336 C CB . THR A 1 305 ? -29.149 -11.778 34.606 1.00 23.03 ? 305 THR A CB 1 ATOM 2337 O OG1 . THR A 1 305 ? -29.200 -10.459 35.156 1.00 22.74 ? 305 THR A OG1 1 ATOM 2338 C CG2 . THR A 1 305 ? -27.906 -12.541 35.174 1.00 23.22 ? 305 THR A CG2 1 ATOM 2339 N N . HIS A 1 306 ? -30.283 -9.861 31.920 1.00 23.70 ? 306 HIS A N 1 ATOM 2340 C CA . HIS A 1 306 ? -31.434 -9.105 31.411 1.00 22.54 ? 306 HIS A CA 1 ATOM 2341 C C . HIS A 1 306 ? -32.371 -8.757 32.521 1.00 24.64 ? 306 HIS A C 1 ATOM 2342 O O . HIS A 1 306 ? -33.616 -8.881 32.350 1.00 24.71 ? 306 HIS A O 1 ATOM 2343 C CB . HIS A 1 306 ? -32.192 -9.935 30.391 1.00 21.86 ? 306 HIS A CB 1 ATOM 2344 C CG . HIS A 1 306 ? -31.288 -10.602 29.412 1.00 20.85 ? 306 HIS A CG 1 ATOM 2345 N ND1 . HIS A 1 306 ? -30.531 -9.900 28.499 1.00 20.85 ? 306 HIS A ND1 1 ATOM 2346 C CD2 . HIS A 1 306 ? -30.934 -11.901 29.281 1.00 23.23 ? 306 HIS A CD2 1 ATOM 2347 C CE1 . HIS A 1 306 ? -29.790 -10.742 27.805 1.00 22.31 ? 306 HIS A CE1 1 ATOM 2348 N NE2 . HIS A 1 306 ? -30.012 -11.966 28.264 1.00 25.83 ? 306 HIS A NE2 1 ATOM 2349 N N . SER A 1 307 ? -31.797 -8.317 33.652 1.00 24.39 ? 307 SER A N 1 ATOM 2350 C CA . SER A 1 307 ? -32.589 -8.023 34.864 1.00 24.98 ? 307 SER A CA 1 ATOM 2351 C C . SER A 1 307 ? -32.099 -6.735 35.463 1.00 24.56 ? 307 SER A C 1 ATOM 2352 O O . SER A 1 307 ? -30.961 -6.353 35.208 1.00 23.44 ? 307 SER A O 1 ATOM 2353 C CB . SER A 1 307 ? -32.386 -9.131 35.928 1.00 25.85 ? 307 SER A CB 1 ATOM 2354 O OG . SER A 1 307 ? -32.350 -10.404 35.292 1.00 29.21 ? 307 SER A OG 1 ATOM 2355 N N . PRO A 1 308 ? -32.913 -6.120 36.342 1.00 24.36 ? 308 PRO A N 1 ATOM 2356 C CA . PRO A 1 308 ? -32.575 -4.841 36.992 1.00 24.55 ? 308 PRO A CA 1 ATOM 2357 C C . PRO A 1 308 ? -31.279 -4.881 37.840 1.00 25.32 ? 308 PRO A C 1 ATOM 2358 O O . PRO A 1 308 ? -30.994 -5.877 38.509 1.00 24.34 ? 308 PRO A O 1 ATOM 2359 C CB . PRO A 1 308 ? -33.797 -4.550 37.864 1.00 24.49 ? 308 PRO A CB 1 ATOM 2360 C CG . PRO A 1 308 ? -34.913 -5.462 37.267 1.00 25.29 ? 308 PRO A CG 1 ATOM 2361 C CD . PRO A 1 308 ? -34.221 -6.647 36.770 1.00 24.74 ? 308 PRO A CD 1 ATOM 2362 N N . VAL A 1 309 ? -30.522 -3.780 37.781 1.00 26.11 ? 309 VAL A N 1 ATOM 2363 C CA . VAL A 1 309 ? -29.220 -3.627 38.430 1.00 25.18 ? 309 VAL A CA 1 ATOM 2364 C C . VAL A 1 309 ? -29.492 -3.731 39.895 1.00 26.08 ? 309 VAL A C 1 ATOM 2365 O O . VAL A 1 309 ? -30.433 -3.105 40.361 1.00 25.82 ? 309 VAL A O 1 ATOM 2366 C CB . VAL A 1 309 ? -28.617 -2.242 38.161 1.00 24.42 ? 309 VAL A CB 1 ATOM 2367 C CG1 . VAL A 1 309 ? -27.265 -2.125 38.814 1.00 22.77 ? 309 VAL A CG1 1 ATOM 2368 C CG2 . VAL A 1 309 ? -28.487 -1.999 36.688 1.00 22.39 ? 309 VAL A CG2 1 ATOM 2369 N N . HIS A 1 310 ? -28.722 -4.567 40.592 1.00 26.45 ? 310 HIS A N 1 ATOM 2370 C CA . HIS A 1 310 ? -28.743 -4.592 42.064 1.00 27.60 ? 310 HIS A CA 1 ATOM 2371 C C . HIS A 1 310 ? -27.381 -4.078 42.524 1.00 26.73 ? 310 HIS A C 1 ATOM 2372 O O . HIS A 1 310 ? -26.348 -4.761 42.425 1.00 26.01 ? 310 HIS A O 1 ATOM 2373 C CB . HIS A 1 310 ? -29.122 -5.968 42.631 1.00 28.25 ? 310 HIS A CB 1 ATOM 2374 C CG . HIS A 1 310 ? -30.379 -6.532 42.020 1.00 36.09 ? 310 HIS A CG 1 ATOM 2375 N ND1 . HIS A 1 310 ? -30.385 -7.645 41.188 1.00 39.52 ? 310 HIS A ND1 1 ATOM 2376 C CD2 . HIS A 1 310 ? -31.673 -6.102 42.081 1.00 40.44 ? 310 HIS A CD2 1 ATOM 2377 C CE1 . HIS A 1 310 ? -31.625 -7.882 40.779 1.00 40.18 ? 310 HIS A CE1 1 ATOM 2378 N NE2 . HIS A 1 310 ? -32.426 -6.964 41.308 1.00 41.18 ? 310 HIS A NE2 1 ATOM 2379 N N . ASP A 1 311 ? -27.389 -2.806 42.930 1.00 25.96 ? 311 ASP A N 1 ATOM 2380 C CA . ASP A 1 311 ? -26.178 -2.167 43.333 1.00 26.07 ? 311 ASP A CA 1 ATOM 2381 C C . ASP A 1 311 ? -26.444 -0.981 44.228 1.00 26.54 ? 311 ASP A C 1 ATOM 2382 O O . ASP A 1 311 ? -27.357 -0.213 43.972 1.00 28.19 ? 311 ASP A O 1 ATOM 2383 C CB . ASP A 1 311 ? -25.403 -1.657 42.129 1.00 24.93 ? 311 ASP A CB 1 ATOM 2384 C CG . ASP A 1 311 ? -24.106 -1.029 42.538 1.00 24.13 ? 311 ASP A CG 1 ATOM 2385 O OD1 . ASP A 1 311 ? -23.100 -1.760 42.763 1.00 26.25 ? 311 ASP A OD1 1 ATOM 2386 O OD2 . ASP A 1 311 ? -24.097 0.203 42.673 1.00 21.61 ? 311 ASP A OD2 1 ATOM 2387 N N . ASP A 1 312 ? -25.604 -0.792 45.230 1.00 26.24 ? 312 ASP A N 1 ATOM 2388 C CA . ASP A 1 312 ? -25.675 0.401 46.025 1.00 27.35 ? 312 ASP A CA 1 ATOM 2389 C C . ASP A 1 312 ? -24.324 1.023 46.285 1.00 26.38 ? 312 ASP A C 1 ATOM 2390 O O . ASP A 1 312 ? -24.111 1.685 47.307 1.00 25.67 ? 312 ASP A O 1 ATOM 2391 C CB . ASP A 1 312 ? -26.384 0.099 47.334 1.00 29.75 ? 312 ASP A CB 1 ATOM 2392 C CG . ASP A 1 312 ? -27.815 0.550 47.294 1.00 35.69 ? 312 ASP A CG 1 ATOM 2393 O OD1 . ASP A 1 312 ? -28.665 -0.206 46.743 1.00 38.74 ? 312 ASP A OD1 1 ATOM 2394 O OD2 . ASP A 1 312 ? -28.058 1.705 47.772 1.00 43.65 ? 312 ASP A OD2 1 ATOM 2395 N N . THR A 1 313 ? -23.418 0.833 45.331 1.00 24.13 ? 313 THR A N 1 ATOM 2396 C CA . THR A 1 313 ? -22.126 1.468 45.394 1.00 21.64 ? 313 THR A CA 1 ATOM 2397 C C . THR A 1 313 ? -21.989 2.686 44.440 1.00 21.84 ? 313 THR A C 1 ATOM 2398 O O . THR A 1 313 ? -22.375 3.814 44.781 1.00 22.07 ? 313 THR A O 1 ATOM 2399 C CB . THR A 1 313 ? -21.049 0.402 45.125 1.00 21.50 ? 313 THR A CB 1 ATOM 2400 O OG1 . THR A 1 313 ? -21.082 0.019 43.744 1.00 17.87 ? 313 THR A OG1 1 ATOM 2401 C CG2 . THR A 1 313 ? -21.296 -0.831 46.024 1.00 18.00 ? 313 THR A CG2 1 ATOM 2402 N N . SER A 1 314 ? -21.417 2.477 43.257 1.00 20.63 ? 314 SER A N 1 ATOM 2403 C CA . SER A 1 314 ? -21.120 3.581 42.368 1.00 20.93 ? 314 SER A CA 1 ATOM 2404 C C . SER A 1 314 ? -22.214 3.838 41.332 1.00 21.56 ? 314 SER A C 1 ATOM 2405 O O . SER A 1 314 ? -22.057 4.728 40.515 1.00 22.04 ? 314 SER A O 1 ATOM 2406 C CB . SER A 1 314 ? -19.810 3.306 41.628 1.00 20.52 ? 314 SER A CB 1 ATOM 2407 O OG . SER A 1 314 ? -19.911 2.092 40.876 1.00 21.39 ? 314 SER A OG 1 ATOM 2408 N N . SER A 1 315 ? -23.290 3.059 41.334 1.00 21.65 ? 315 SER A N 1 ATOM 2409 C CA . SER A 1 315 ? -24.256 3.191 40.288 1.00 22.57 ? 315 SER A CA 1 ATOM 2410 C C . SER A 1 315 ? -25.207 4.371 40.530 1.00 23.55 ? 315 SER A C 1 ATOM 2411 O O . SER A 1 315 ? -25.543 4.720 41.678 1.00 24.27 ? 315 SER A O 1 ATOM 2412 C CB . SER A 1 315 ? -25.000 1.875 40.075 1.00 21.84 ? 315 SER A CB 1 ATOM 2413 O OG . SER A 1 315 ? -26.066 1.765 40.971 1.00 22.57 ? 315 SER A OG 1 ATOM 2414 N N . ASN A 1 316 ? -25.584 5.028 39.451 1.00 24.27 ? 316 ASN A N 1 ATOM 2415 C CA . ASN A 1 316 ? -26.613 6.019 39.507 1.00 25.26 ? 316 ASN A CA 1 ATOM 2416 C C . ASN A 1 316 ? -27.976 5.325 39.205 1.00 26.09 ? 316 ASN A C 1 ATOM 2417 O O . ASN A 1 316 ? -28.161 4.757 38.117 1.00 25.96 ? 316 ASN A O 1 ATOM 2418 C CB . ASN A 1 316 ? -26.247 7.140 38.527 1.00 25.79 ? 316 ASN A CB 1 ATOM 2419 C CG . ASN A 1 316 ? -27.260 8.245 38.496 1.00 25.81 ? 316 ASN A CG 1 ATOM 2420 O OD1 . ASN A 1 316 ? -28.434 7.984 38.675 1.00 29.39 ? 316 ASN A OD1 1 ATOM 2421 N ND2 . ASN A 1 316 ? -26.819 9.475 38.257 1.00 26.68 ? 316 ASN A ND2 1 ATOM 2422 N N . HIS A 1 317 ? -28.892 5.368 40.184 1.00 25.76 ? 317 HIS A N 1 ATOM 2423 C CA . HIS A 1 317 ? -30.203 4.710 40.141 1.00 26.82 ? 317 HIS A CA 1 ATOM 2424 C C . HIS A 1 317 ? -31.160 5.433 39.194 1.00 26.51 ? 317 HIS A C 1 ATOM 2425 O O . HIS A 1 317 ? -32.060 4.831 38.623 1.00 25.63 ? 317 HIS A O 1 ATOM 2426 C CB . HIS A 1 317 ? -30.831 4.630 41.545 1.00 26.66 ? 317 HIS A CB 1 ATOM 2427 C CG . HIS A 1 317 ? -30.036 3.815 42.516 1.00 31.47 ? 317 HIS A CG 1 ATOM 2428 N ND1 . HIS A 1 317 ? -29.904 2.450 42.411 1.00 37.38 ? 317 HIS A ND1 1 ATOM 2429 C CD2 . HIS A 1 317 ? -29.307 4.171 43.593 1.00 35.83 ? 317 HIS A CD2 1 ATOM 2430 C CE1 . HIS A 1 317 ? -29.140 1.999 43.387 1.00 35.56 ? 317 HIS A CE1 1 ATOM 2431 N NE2 . HIS A 1 317 ? -28.763 3.025 44.120 1.00 36.51 ? 317 HIS A NE2 1 ATOM 2432 N N . THR A 1 318 ? -30.976 6.730 39.032 1.00 26.54 ? 318 THR A N 1 ATOM 2433 C CA . THR A 1 318 ? -31.859 7.435 38.122 1.00 27.19 ? 318 THR A CA 1 ATOM 2434 C C . THR A 1 318 ? -31.554 6.925 36.717 1.00 26.93 ? 318 THR A C 1 ATOM 2435 O O . THR A 1 318 ? -32.482 6.558 35.950 1.00 27.43 ? 318 THR A O 1 ATOM 2436 C CB . THR A 1 318 ? -31.675 8.948 38.190 1.00 27.09 ? 318 THR A CB 1 ATOM 2437 O OG1 . THR A 1 318 ? -32.023 9.391 39.486 1.00 28.48 ? 318 THR A OG1 1 ATOM 2438 C CG2 . THR A 1 318 ? -32.617 9.652 37.188 1.00 28.33 ? 318 THR A CG2 1 ATOM 2439 N N . LEU A 1 319 ? -30.261 6.876 36.400 1.00 25.98 ? 319 LEU A N 1 ATOM 2440 C CA . LEU A 1 319 ? -29.784 6.349 35.116 1.00 25.10 ? 319 LEU A CA 1 ATOM 2441 C C . LEU A 1 319 ? -30.130 4.887 34.888 1.00 25.52 ? 319 LEU A C 1 ATOM 2442 O O . LEU A 1 319 ? -30.568 4.522 33.779 1.00 26.57 ? 319 LEU A O 1 ATOM 2443 C CB . LEU A 1 319 ? -28.291 6.541 34.974 1.00 24.49 ? 319 LEU A CB 1 ATOM 2444 C CG . LEU A 1 319 ? -27.629 7.586 34.072 1.00 25.70 ? 319 LEU A CG 1 ATOM 2445 C CD1 . LEU A 1 319 ? -28.466 8.756 33.705 1.00 24.74 ? 319 LEU A CD1 1 ATOM 2446 C CD2 . LEU A 1 319 ? -26.298 8.039 34.662 1.00 21.58 ? 319 LEU A CD2 1 ATOM 2447 N N . ASP A 1 320 ? -29.970 4.042 35.912 1.00 24.22 ? 320 ASP A N 1 ATOM 2448 C CA . ASP A 1 320 ? -30.026 2.617 35.682 1.00 23.96 ? 320 ASP A CA 1 ATOM 2449 C C . ASP A 1 320 ? -31.432 2.019 35.786 1.00 24.28 ? 320 ASP A C 1 ATOM 2450 O O . ASP A 1 320 ? -31.671 0.895 35.358 1.00 24.48 ? 320 ASP A O 1 ATOM 2451 C CB . ASP A 1 320 ? -29.025 1.838 36.579 1.00 22.75 ? 320 ASP A CB 1 ATOM 2452 C CG . ASP A 1 320 ? -27.607 1.942 36.101 1.00 23.74 ? 320 ASP A CG 1 ATOM 2453 O OD1 . ASP A 1 320 ? -27.298 2.852 35.297 1.00 23.16 ? 320 ASP A OD1 1 ATOM 2454 O OD2 . ASP A 1 320 ? -26.766 1.114 36.524 1.00 25.05 ? 320 ASP A OD2 1 ATOM 2455 N N . SER A 1 321 ? -32.356 2.721 36.398 1.00 25.21 ? 321 SER A N 1 ATOM 2456 C CA . SER A 1 321 ? -33.670 2.115 36.555 1.00 27.15 ? 321 SER A CA 1 ATOM 2457 C C . SER A 1 321 ? -34.596 2.471 35.378 1.00 27.58 ? 321 SER A C 1 ATOM 2458 O O . SER A 1 321 ? -35.721 2.020 35.365 1.00 28.14 ? 321 SER A O 1 ATOM 2459 C CB . SER A 1 321 ? -34.313 2.496 37.905 1.00 27.40 ? 321 SER A CB 1 ATOM 2460 O OG . SER A 1 321 ? -34.734 3.844 37.849 1.00 28.21 ? 321 SER A OG 1 ATOM 2461 N N . SER A 1 322 ? -34.114 3.300 34.439 1.00 28.30 ? 322 SER A N 1 ATOM 2462 C CA . SER A 1 322 ? -34.824 3.687 33.179 1.00 28.81 ? 322 SER A CA 1 ATOM 2463 C C . SER A 1 322 ? -34.297 2.983 31.896 1.00 28.25 ? 322 SER A C 1 ATOM 2464 O O . SER A 1 322 ? -33.097 3.100 31.576 1.00 28.23 ? 322 SER A O 1 ATOM 2465 C CB . SER A 1 322 ? -34.774 5.203 32.999 1.00 29.30 ? 322 SER A CB 1 ATOM 2466 O OG . SER A 1 322 ? -34.959 5.567 31.634 1.00 33.20 ? 322 SER A OG 1 ATOM 2467 N N . PRO A 1 323 ? -35.189 2.267 31.154 1.00 27.64 ? 323 PRO A N 1 ATOM 2468 C CA . PRO A 1 323 ? -34.758 1.503 29.970 1.00 26.76 ? 323 PRO A CA 1 ATOM 2469 C C . PRO A 1 323 ? -34.040 2.366 28.934 1.00 26.79 ? 323 PRO A C 1 ATOM 2470 O O . PRO A 1 323 ? -33.176 1.858 28.234 1.00 27.10 ? 323 PRO A O 1 ATOM 2471 C CB . PRO A 1 323 ? -36.071 0.937 29.382 1.00 27.08 ? 323 PRO A CB 1 ATOM 2472 C CG . PRO A 1 323 ? -37.055 0.936 30.510 1.00 29.66 ? 323 PRO A CG 1 ATOM 2473 C CD . PRO A 1 323 ? -36.634 2.114 31.439 1.00 27.55 ? 323 PRO A CD 1 ATOM 2474 N N . ALA A 1 324 ? -34.404 3.649 28.862 1.00 26.14 ? 324 ALA A N 1 ATOM 2475 C CA . ALA A 1 324 ? -33.786 4.647 28.004 1.00 25.54 ? 324 ALA A CA 1 ATOM 2476 C C . ALA A 1 324 ? -32.284 4.849 28.244 1.00 24.81 ? 324 ALA A C 1 ATOM 2477 O O . ALA A 1 324 ? -31.526 5.000 27.292 1.00 25.86 ? 324 ALA A O 1 ATOM 2478 C CB . ALA A 1 324 ? -34.515 6.000 28.156 1.00 25.09 ? 324 ALA A CB 1 ATOM 2479 N N . THR A 1 325 ? -31.869 4.892 29.510 1.00 23.78 ? 325 THR A N 1 ATOM 2480 C CA . THR A 1 325 ? -30.478 5.158 29.868 1.00 22.51 ? 325 THR A CA 1 ATOM 2481 C C . THR A 1 325 ? -29.804 3.896 30.392 1.00 22.23 ? 325 THR A C 1 ATOM 2482 O O . THR A 1 325 ? -28.602 3.879 30.611 1.00 23.29 ? 325 THR A O 1 ATOM 2483 C CB . THR A 1 325 ? -30.375 6.306 30.862 1.00 22.20 ? 325 THR A CB 1 ATOM 2484 O OG1 . THR A 1 325 ? -31.440 6.197 31.824 1.00 21.46 ? 325 THR A OG1 1 ATOM 2485 C CG2 . THR A 1 325 ? -30.578 7.648 30.087 1.00 23.64 ? 325 THR A CG2 1 ATOM 2486 N N . PHE A 1 326 ? -30.558 2.828 30.576 1.00 20.70 ? 326 PHE A N 1 ATOM 2487 C CA . PHE A 1 326 ? -29.932 1.542 30.873 1.00 21.07 ? 326 PHE A CA 1 ATOM 2488 C C . PHE A 1 326 ? -30.776 0.364 30.340 1.00 21.62 ? 326 PHE A C 1 ATOM 2489 O O . PHE A 1 326 ? -31.357 -0.388 31.145 1.00 21.69 ? 326 PHE A O 1 ATOM 2490 C CB . PHE A 1 326 ? -29.594 1.354 32.371 1.00 19.73 ? 326 PHE A CB 1 ATOM 2491 C CG . PHE A 1 326 ? -28.582 0.250 32.639 1.00 19.60 ? 326 PHE A CG 1 ATOM 2492 C CD1 . PHE A 1 326 ? -27.218 0.511 32.557 1.00 17.58 ? 326 PHE A CD1 1 ATOM 2493 C CD2 . PHE A 1 326 ? -28.998 -1.038 32.936 1.00 17.30 ? 326 PHE A CD2 1 ATOM 2494 C CE1 . PHE A 1 326 ? -26.291 -0.526 32.792 1.00 18.07 ? 326 PHE A CE1 1 ATOM 2495 C CE2 . PHE A 1 326 ? -28.090 -2.098 33.184 1.00 19.53 ? 326 PHE A CE2 1 ATOM 2496 C CZ . PHE A 1 326 ? -26.744 -1.865 33.127 1.00 18.14 ? 326 PHE A CZ 1 ATOM 2497 N N . PRO A 1 327 ? -30.803 0.186 28.997 1.00 22.01 ? 327 PRO A N 1 ATOM 2498 C CA . PRO A 1 327 ? -31.596 -0.873 28.370 1.00 22.23 ? 327 PRO A CA 1 ATOM 2499 C C . PRO A 1 327 ? -30.986 -2.218 28.663 1.00 22.07 ? 327 PRO A C 1 ATOM 2500 O O . PRO A 1 327 ? -29.764 -2.376 28.592 1.00 21.62 ? 327 PRO A O 1 ATOM 2501 C CB . PRO A 1 327 ? -31.461 -0.541 26.848 1.00 23.58 ? 327 PRO A CB 1 ATOM 2502 C CG . PRO A 1 327 ? -30.141 0.139 26.731 1.00 21.15 ? 327 PRO A CG 1 ATOM 2503 C CD . PRO A 1 327 ? -30.000 0.932 27.988 1.00 21.80 ? 327 PRO A CD 1 ATOM 2504 N N . LEU A 1 328 ? -31.832 -3.189 28.956 1.00 22.19 ? 328 LEU A N 1 ATOM 2505 C CA . LEU A 1 328 ? -31.377 -4.517 29.397 1.00 22.29 ? 328 LEU A CA 1 ATOM 2506 C C . LEU A 1 328 ? -31.226 -5.577 28.294 1.00 22.98 ? 328 LEU A C 1 ATOM 2507 O O . LEU A 1 328 ? -30.834 -6.730 28.577 1.00 22.41 ? 328 LEU A O 1 ATOM 2508 C CB . LEU A 1 328 ? -32.347 -5.032 30.478 1.00 22.27 ? 328 LEU A CB 1 ATOM 2509 C CG . LEU A 1 328 ? -32.354 -4.138 31.714 1.00 22.88 ? 328 LEU A CG 1 ATOM 2510 C CD1 . LEU A 1 328 ? -33.497 -4.417 32.681 1.00 18.69 ? 328 LEU A CD1 1 ATOM 2511 C CD2 . LEU A 1 328 ? -30.911 -4.220 32.370 1.00 20.74 ? 328 LEU A CD2 1 ATOM 2512 N N . ASN A 1 329 ? -31.563 -5.225 27.052 1.00 23.01 ? 329 ASN A N 1 ATOM 2513 C CA . ASN A 1 329 ? -31.635 -6.240 25.984 1.00 25.30 ? 329 ASN A CA 1 ATOM 2514 C C . ASN A 1 329 ? -31.096 -5.761 24.659 1.00 24.46 ? 329 ASN A C 1 ATOM 2515 O O . ASN A 1 329 ? -31.753 -5.963 23.648 1.00 25.69 ? 329 ASN A O 1 ATOM 2516 C CB . ASN A 1 329 ? -33.110 -6.644 25.765 1.00 26.49 ? 329 ASN A CB 1 ATOM 2517 C CG . ASN A 1 329 ? -33.566 -7.702 26.738 1.00 32.46 ? 329 ASN A CG 1 ATOM 2518 O OD1 . ASN A 1 329 ? -33.010 -8.816 26.764 1.00 38.73 ? 329 ASN A OD1 1 ATOM 2519 N ND2 . ASN A 1 329 ? -34.573 -7.369 27.565 1.00 35.38 ? 329 ASN A ND2 1 ATOM 2520 N N . SER A 1 330 ? -29.943 -5.097 24.659 1.00 22.60 ? 330 SER A N 1 ATOM 2521 C CA . SER A 1 330 ? -29.478 -4.361 23.474 1.00 20.04 ? 330 SER A CA 1 ATOM 2522 C C . SER A 1 330 ? -28.496 -5.176 22.676 1.00 18.82 ? 330 SER A C 1 ATOM 2523 O O . SER A 1 330 ? -28.077 -4.728 21.626 1.00 19.31 ? 330 SER A O 1 ATOM 2524 C CB . SER A 1 330 ? -28.716 -3.128 23.893 1.00 19.30 ? 330 SER A CB 1 ATOM 2525 O OG . SER A 1 330 ? -29.555 -2.355 24.694 1.00 20.60 ? 330 SER A OG 1 ATOM 2526 N N . THR A 1 331 ? -28.083 -6.313 23.225 1.00 16.16 ? 331 THR A N 1 ATOM 2527 C CA . THR A 1 331 ? -27.121 -7.212 22.623 1.00 16.65 ? 331 THR A CA 1 ATOM 2528 C C . THR A 1 331 ? -25.703 -6.710 22.513 1.00 16.34 ? 331 THR A C 1 ATOM 2529 O O . THR A 1 331 ? -24.746 -7.461 22.756 1.00 17.12 ? 331 THR A O 1 ATOM 2530 C CB . THR A 1 331 ? -27.586 -7.830 21.233 1.00 16.52 ? 331 THR A CB 1 ATOM 2531 O OG1 . THR A 1 331 ? -28.818 -8.525 21.440 1.00 18.22 ? 331 THR A OG1 1 ATOM 2532 C CG2 . THR A 1 331 ? -26.621 -8.793 20.735 1.00 12.07 ? 331 THR A CG2 1 ATOM 2533 N N . LEU A 1 332 ? -25.556 -5.465 22.126 1.00 15.65 ? 332 LEU A N 1 ATOM 2534 C CA . LEU A 1 332 ? -24.235 -4.903 22.011 1.00 16.24 ? 332 LEU A CA 1 ATOM 2535 C C . LEU A 1 332 ? -24.165 -3.645 22.841 1.00 16.17 ? 332 LEU A C 1 ATOM 2536 O O . LEU A 1 332 ? -25.096 -2.812 22.823 1.00 16.32 ? 332 LEU A O 1 ATOM 2537 C CB . LEU A 1 332 ? -23.897 -4.595 20.547 1.00 16.26 ? 332 LEU A CB 1 ATOM 2538 C CG . LEU A 1 332 ? -23.904 -5.742 19.528 1.00 16.94 ? 332 LEU A CG 1 ATOM 2539 C CD1 . LEU A 1 332 ? -23.782 -5.184 18.117 1.00 17.31 ? 332 LEU A CD1 1 ATOM 2540 C CD2 . LEU A 1 332 ? -22.767 -6.672 19.792 1.00 15.95 ? 332 LEU A CD2 1 ATOM 2541 N N . TYR A 1 333 ? -23.030 -3.487 23.508 1.00 16.05 ? 333 TYR A N 1 ATOM 2542 C CA . TYR A 1 333 ? -22.795 -2.394 24.445 1.00 14.98 ? 333 TYR A CA 1 ATOM 2543 C C . TYR A 1 333 ? -21.351 -1.989 24.289 1.00 15.55 ? 333 TYR A C 1 ATOM 2544 O O . TYR A 1 333 ? -20.469 -2.825 23.995 1.00 15.29 ? 333 TYR A O 1 ATOM 2545 C CB . TYR A 1 333 ? -23.057 -2.812 25.922 1.00 14.51 ? 333 TYR A CB 1 ATOM 2546 C CG . TYR A 1 333 ? -24.515 -3.212 26.267 1.00 13.34 ? 333 TYR A CG 1 ATOM 2547 C CD1 . TYR A 1 333 ? -25.443 -2.258 26.655 1.00 11.59 ? 333 TYR A CD1 1 ATOM 2548 C CD2 . TYR A 1 333 ? -24.939 -4.568 26.204 1.00 14.51 ? 333 TYR A CD2 1 ATOM 2549 C CE1 . TYR A 1 333 ? -26.793 -2.616 26.994 1.00 10.86 ? 333 TYR A CE1 1 ATOM 2550 C CE2 . TYR A 1 333 ? -26.255 -4.938 26.544 1.00 14.28 ? 333 TYR A CE2 1 ATOM 2551 C CZ . TYR A 1 333 ? -27.171 -3.942 26.944 1.00 14.66 ? 333 TYR A CZ 1 ATOM 2552 O OH . TYR A 1 333 ? -28.479 -4.256 27.230 1.00 13.55 ? 333 TYR A OH 1 ATOM 2553 N N . ALA A 1 334 ? -21.127 -0.682 24.437 1.00 15.69 ? 334 ALA A N 1 ATOM 2554 C CA . ALA A 1 334 ? -19.812 -0.099 24.394 1.00 16.02 ? 334 ALA A CA 1 ATOM 2555 C C . ALA A 1 334 ? -19.753 0.935 25.520 1.00 16.80 ? 334 ALA A C 1 ATOM 2556 O O . ALA A 1 334 ? -20.723 1.695 25.695 1.00 17.58 ? 334 ALA A O 1 ATOM 2557 C CB . ALA A 1 334 ? -19.524 0.522 23.050 1.00 14.20 ? 334 ALA A CB 1 ATOM 2558 N N . ASP A 1 335 ? -18.671 0.878 26.334 1.00 16.01 ? 335 ASP A N 1 ATOM 2559 C CA . ASP A 1 335 ? -18.435 1.828 27.413 1.00 15.57 ? 335 ASP A CA 1 ATOM 2560 C C . ASP A 1 335 ? -17.014 2.366 27.258 1.00 16.08 ? 335 ASP A C 1 ATOM 2561 O O . ASP A 1 335 ? -16.119 1.613 26.889 1.00 15.72 ? 335 ASP A O 1 ATOM 2562 C CB . ASP A 1 335 ? -18.669 1.145 28.760 1.00 16.64 ? 335 ASP A CB 1 ATOM 2563 C CG . ASP A 1 335 ? -20.163 0.990 29.125 1.00 17.09 ? 335 ASP A CG 1 ATOM 2564 O OD1 . ASP A 1 335 ? -20.988 1.913 28.902 1.00 18.23 ? 335 ASP A OD1 1 ATOM 2565 O OD2 . ASP A 1 335 ? -20.512 -0.074 29.677 1.00 16.95 ? 335 ASP A OD2 1 ATOM 2566 N N . PHE A 1 336 ? -16.825 3.672 27.509 1.00 16.20 ? 336 PHE A N 1 ATOM 2567 C CA . PHE A 1 336 ? -15.533 4.371 27.403 1.00 16.60 ? 336 PHE A CA 1 ATOM 2568 C C . PHE A 1 336 ? -15.119 5.082 28.692 1.00 17.09 ? 336 PHE A C 1 ATOM 2569 O O . PHE A 1 336 ? -15.923 5.807 29.312 1.00 16.72 ? 336 PHE A O 1 ATOM 2570 C CB . PHE A 1 336 ? -15.554 5.412 26.210 1.00 16.97 ? 336 PHE A CB 1 ATOM 2571 C CG . PHE A 1 336 ? -15.831 4.766 24.916 1.00 14.82 ? 336 PHE A CG 1 ATOM 2572 C CD1 . PHE A 1 336 ? -17.144 4.460 24.569 1.00 14.05 ? 336 PHE A CD1 1 ATOM 2573 C CD2 . PHE A 1 336 ? -14.797 4.327 24.137 1.00 12.79 ? 336 PHE A CD2 1 ATOM 2574 C CE1 . PHE A 1 336 ? -17.430 3.766 23.406 1.00 12.27 ? 336 PHE A CE1 1 ATOM 2575 C CE2 . PHE A 1 336 ? -15.029 3.614 22.994 1.00 14.12 ? 336 PHE A CE2 1 ATOM 2576 C CZ . PHE A 1 336 ? -16.363 3.333 22.604 1.00 13.71 ? 336 PHE A CZ 1 ATOM 2577 N N . SER A 1 337 ? -13.855 4.932 29.084 1.00 17.03 ? 337 SER A N 1 ATOM 2578 C CA . SER A 1 337 ? -13.425 5.377 30.418 1.00 17.58 ? 337 SER A CA 1 ATOM 2579 C C . SER A 1 337 ? -11.932 5.539 30.496 1.00 17.93 ? 337 SER A C 1 ATOM 2580 O O . SER A 1 337 ? -11.241 5.504 29.459 1.00 18.52 ? 337 SER A O 1 ATOM 2581 C CB . SER A 1 337 ? -13.898 4.380 31.498 1.00 17.10 ? 337 SER A CB 1 ATOM 2582 O OG . SER A 1 337 ? -13.881 5.017 32.753 1.00 18.89 ? 337 SER A OG 1 ATOM 2583 N N . HIS A 1 338 ? -11.448 5.704 31.738 1.00 17.72 ? 338 HIS A N 1 ATOM 2584 C CA . HIS A 1 338 ? -10.044 5.972 32.085 1.00 17.27 ? 338 HIS A CA 1 ATOM 2585 C C . HIS A 1 338 ? -9.412 4.665 32.552 1.00 17.16 ? 338 HIS A C 1 ATOM 2586 O O . HIS A 1 338 ? -10.119 3.740 32.934 1.00 16.54 ? 338 HIS A O 1 ATOM 2587 C CB . HIS A 1 338 ? -9.945 7.007 33.237 1.00 15.77 ? 338 HIS A CB 1 ATOM 2588 C CG . HIS A 1 338 ? -10.607 8.314 32.941 1.00 17.10 ? 338 HIS A CG 1 ATOM 2589 N ND1 . HIS A 1 338 ? -9.941 9.365 32.332 1.00 9.92 ? 338 HIS A ND1 1 ATOM 2590 C CD2 . HIS A 1 338 ? -11.872 8.747 33.168 1.00 16.88 ? 338 HIS A CD2 1 ATOM 2591 C CE1 . HIS A 1 338 ? -10.769 10.386 32.202 1.00 13.78 ? 338 HIS A CE1 1 ATOM 2592 N NE2 . HIS A 1 338 ? -11.939 10.046 32.722 1.00 16.77 ? 338 HIS A NE2 1 ATOM 2593 N N . ASP A 1 339 ? -8.078 4.596 32.545 1.00 17.58 ? 339 ASP A N 1 ATOM 2594 C CA . ASP A 1 339 ? -7.375 3.374 32.962 1.00 17.83 ? 339 ASP A CA 1 ATOM 2595 C C . ASP A 1 339 ? -7.658 2.950 34.445 1.00 17.73 ? 339 ASP A C 1 ATOM 2596 O O . ASP A 1 339 ? -7.798 1.776 34.748 1.00 18.74 ? 339 ASP A O 1 ATOM 2597 C CB . ASP A 1 339 ? -5.890 3.555 32.733 1.00 17.91 ? 339 ASP A CB 1 ATOM 2598 C CG . ASP A 1 339 ? -5.342 4.763 33.460 1.00 20.86 ? 339 ASP A CG 1 ATOM 2599 O OD1 . ASP A 1 339 ? -6.026 5.380 34.291 1.00 26.68 ? 339 ASP A OD1 1 ATOM 2600 O OD2 . ASP A 1 339 ? -4.234 5.173 33.171 1.00 24.93 ? 339 ASP A OD2 1 ATOM 2601 N N . ASN A 1 340 ? -7.773 3.917 35.344 1.00 16.03 ? 340 ASN A N 1 ATOM 2602 C CA . ASN A 1 340 ? -7.849 3.615 36.750 1.00 16.11 ? 340 ASN A CA 1 ATOM 2603 C C . ASN A 1 340 ? -9.153 2.910 37.046 1.00 15.33 ? 340 ASN A C 1 ATOM 2604 O O . ASN A 1 340 ? -9.166 1.958 37.813 1.00 14.77 ? 340 ASN A O 1 ATOM 2605 C CB . ASN A 1 340 ? -7.723 4.900 37.635 1.00 14.62 ? 340 ASN A CB 1 ATOM 2606 C CG . ASN A 1 340 ? -6.288 5.471 37.709 1.00 17.31 ? 340 ASN A CG 1 ATOM 2607 O OD1 . ASN A 1 340 ? -5.264 4.797 37.396 1.00 15.99 ? 340 ASN A OD1 1 ATOM 2608 N ND2 . ASN A 1 340 ? -6.205 6.750 38.130 1.00 16.39 ? 340 ASN A ND2 1 ATOM 2609 N N . GLY A 1 341 ? -10.262 3.422 36.510 1.00 14.34 ? 341 GLY A N 1 ATOM 2610 C CA . GLY A 1 341 ? -11.558 2.753 36.645 1.00 13.65 ? 341 GLY A CA 1 ATOM 2611 C C . GLY A 1 341 ? -11.503 1.386 35.975 1.00 14.92 ? 341 GLY A C 1 ATOM 2612 O O . GLY A 1 341 ? -12.093 0.428 36.467 1.00 14.88 ? 341 GLY A O 1 ATOM 2613 N N . ILE A 1 342 ? -10.747 1.249 34.877 1.00 14.27 ? 342 ILE A N 1 ATOM 2614 C CA . ILE A 1 342 ? -10.769 -0.040 34.153 1.00 14.79 ? 342 ILE A CA 1 ATOM 2615 C C . ILE A 1 342 ? -10.007 -1.098 34.957 1.00 16.63 ? 342 ILE A C 1 ATOM 2616 O O . ILE A 1 342 ? -10.375 -2.267 35.006 1.00 17.32 ? 342 ILE A O 1 ATOM 2617 C CB . ILE A 1 342 ? -10.216 0.147 32.703 1.00 14.74 ? 342 ILE A CB 1 ATOM 2618 C CG1 . ILE A 1 342 ? -11.215 0.990 31.885 1.00 13.94 ? 342 ILE A CG1 1 ATOM 2619 C CG2 . ILE A 1 342 ? -9.951 -1.138 32.051 1.00 12.54 ? 342 ILE A CG2 1 ATOM 2620 C CD1 . ILE A 1 342 ? -10.697 1.399 30.546 1.00 9.15 ? 342 ILE A CD1 1 ATOM 2621 N N . ILE A 1 343 ? -8.928 -0.681 35.618 1.00 17.75 ? 343 ILE A N 1 ATOM 2622 C CA . ILE A 1 343 ? -8.205 -1.577 36.499 1.00 16.12 ? 343 ILE A CA 1 ATOM 2623 C C . ILE A 1 343 ? -9.185 -2.100 37.581 1.00 15.82 ? 343 ILE A C 1 ATOM 2624 O O . ILE A 1 343 ? -9.331 -3.316 37.770 1.00 16.52 ? 343 ILE A O 1 ATOM 2625 C CB . ILE A 1 343 ? -6.961 -0.845 37.099 1.00 16.14 ? 343 ILE A CB 1 ATOM 2626 C CG1 . ILE A 1 343 ? -5.897 -0.586 36.019 1.00 14.44 ? 343 ILE A CG1 1 ATOM 2627 C CG2 . ILE A 1 343 ? -6.430 -1.618 38.357 1.00 13.40 ? 343 ILE A CG2 1 ATOM 2628 C CD1 . ILE A 1 343 ? -5.015 -1.804 35.585 1.00 12.17 ? 343 ILE A CD1 1 ATOM 2629 N N . SER A 1 344 ? -9.907 -1.211 38.264 1.00 14.82 ? 344 SER A N 1 ATOM 2630 C CA . SER A 1 344 ? -10.797 -1.660 39.348 1.00 13.70 ? 344 SER A CA 1 ATOM 2631 C C . SER A 1 344 ? -11.830 -2.678 38.889 1.00 15.18 ? 344 SER A C 1 ATOM 2632 O O . SER A 1 344 ? -12.150 -3.663 39.605 1.00 15.72 ? 344 SER A O 1 ATOM 2633 C CB . SER A 1 344 ? -11.484 -0.491 40.058 1.00 12.72 ? 344 SER A CB 1 ATOM 2634 O OG . SER A 1 344 ? -10.520 0.450 40.500 1.00 13.55 ? 344 SER A OG 1 ATOM 2635 N N . ILE A 1 345 ? -12.382 -2.430 37.704 1.00 15.35 ? 345 ILE A N 1 ATOM 2636 C CA . ILE A 1 345 ? -13.373 -3.302 37.118 1.00 14.29 ? 345 ILE A CA 1 ATOM 2637 C C . ILE A 1 345 ? -12.791 -4.673 36.757 1.00 13.55 ? 345 ILE A C 1 ATOM 2638 O O . ILE A 1 345 ? -13.432 -5.687 36.986 1.00 11.95 ? 345 ILE A O 1 ATOM 2639 C CB . ILE A 1 345 ? -14.030 -2.641 35.868 1.00 15.42 ? 345 ILE A CB 1 ATOM 2640 C CG1 . ILE A 1 345 ? -14.729 -1.356 36.270 1.00 13.35 ? 345 ILE A CG1 1 ATOM 2641 C CG2 . ILE A 1 345 ? -14.944 -3.670 35.179 1.00 12.23 ? 345 ILE A CG2 1 ATOM 2642 C CD1 . ILE A 1 345 ? -15.024 -0.362 35.140 1.00 11.35 ? 345 ILE A CD1 1 ATOM 2643 N N . LEU A 1 346 ? -11.585 -4.684 36.185 1.00 13.05 ? 346 LEU A N 1 ATOM 2644 C CA . LEU A 1 346 ? -10.940 -5.922 35.813 1.00 13.26 ? 346 LEU A CA 1 ATOM 2645 C C . LEU A 1 346 ? -10.807 -6.826 37.101 1.00 15.30 ? 346 LEU A C 1 ATOM 2646 O O . LEU A 1 346 ? -11.099 -8.058 37.093 1.00 15.58 ? 346 LEU A O 1 ATOM 2647 C CB . LEU A 1 346 ? -9.605 -5.609 35.106 1.00 12.24 ? 346 LEU A CB 1 ATOM 2648 C CG . LEU A 1 346 ? -9.506 -5.001 33.683 1.00 13.77 ? 346 LEU A CG 1 ATOM 2649 C CD1 . LEU A 1 346 ? -8.000 -4.772 33.214 1.00 10.13 ? 346 LEU A CD1 1 ATOM 2650 C CD2 . LEU A 1 346 ? -10.145 -5.871 32.604 1.00 12.68 ? 346 LEU A CD2 1 ATOM 2651 N N . PHE A 1 347 ? -10.495 -6.192 38.242 1.00 14.83 ? 347 PHE A N 1 ATOM 2652 C CA . PHE A 1 347 ? -10.280 -6.917 39.447 1.00 15.75 ? 347 PHE A CA 1 ATOM 2653 C C . PHE A 1 347 ? -11.562 -7.283 40.146 1.00 16.39 ? 347 PHE A C 1 ATOM 2654 O O . PHE A 1 347 ? -11.642 -8.393 40.720 1.00 17.44 ? 347 PHE A O 1 ATOM 2655 C CB . PHE A 1 347 ? -9.397 -6.118 40.370 1.00 15.68 ? 347 PHE A CB 1 ATOM 2656 C CG . PHE A 1 347 ? -7.937 -6.296 40.072 1.00 16.22 ? 347 PHE A CG 1 ATOM 2657 C CD1 . PHE A 1 347 ? -7.232 -7.393 40.612 1.00 13.70 ? 347 PHE A CD1 1 ATOM 2658 C CD2 . PHE A 1 347 ? -7.270 -5.377 39.272 1.00 10.24 ? 347 PHE A CD2 1 ATOM 2659 C CE1 . PHE A 1 347 ? -5.852 -7.548 40.323 1.00 16.45 ? 347 PHE A CE1 1 ATOM 2660 C CE2 . PHE A 1 347 ? -5.877 -5.537 38.982 1.00 15.74 ? 347 PHE A CE2 1 ATOM 2661 C CZ . PHE A 1 347 ? -5.179 -6.612 39.525 1.00 12.78 ? 347 PHE A CZ 1 ATOM 2662 N N . ALA A 1 348 ? -12.544 -6.384 40.108 1.00 15.03 ? 348 ALA A N 1 ATOM 2663 C CA . ALA A 1 348 ? -13.873 -6.710 40.654 1.00 16.05 ? 348 ALA A CA 1 ATOM 2664 C C . ALA A 1 348 ? -14.523 -7.857 39.887 1.00 16.50 ? 348 ALA A C 1 ATOM 2665 O O . ALA A 1 348 ? -15.334 -8.572 40.464 1.00 18.01 ? 348 ALA A O 1 ATOM 2666 C CB . ALA A 1 348 ? -14.785 -5.498 40.602 1.00 14.66 ? 348 ALA A CB 1 ATOM 2667 N N . LEU A 1 349 ? -14.136 -8.082 38.623 1.00 16.28 ? 349 LEU A N 1 ATOM 2668 C CA . LEU A 1 349 ? -14.768 -9.177 37.835 1.00 17.23 ? 349 LEU A CA 1 ATOM 2669 C C . LEU A 1 349 ? -14.035 -10.473 38.090 1.00 18.31 ? 349 LEU A C 1 ATOM 2670 O O . LEU A 1 349 ? -14.308 -11.473 37.425 1.00 19.06 ? 349 LEU A O 1 ATOM 2671 C CB . LEU A 1 349 ? -14.734 -8.908 36.333 1.00 15.35 ? 349 LEU A CB 1 ATOM 2672 C CG . LEU A 1 349 ? -15.596 -7.723 35.892 1.00 17.74 ? 349 LEU A CG 1 ATOM 2673 C CD1 . LEU A 1 349 ? -15.334 -7.395 34.450 1.00 15.36 ? 349 LEU A CD1 1 ATOM 2674 C CD2 . LEU A 1 349 ? -17.089 -8.118 36.156 1.00 19.12 ? 349 LEU A CD2 1 ATOM 2675 N N . GLY A 1 350 ? -13.041 -10.437 38.988 1.00 18.51 ? 350 GLY A N 1 ATOM 2676 C CA . GLY A 1 350 ? -12.323 -11.651 39.335 1.00 19.56 ? 350 GLY A CA 1 ATOM 2677 C C . GLY A 1 350 ? -11.218 -12.032 38.349 1.00 19.67 ? 350 GLY A C 1 ATOM 2678 O O . GLY A 1 350 ? -10.601 -13.089 38.508 1.00 19.71 ? 350 GLY A O 1 ATOM 2679 N N . LEU A 1 351 ? -10.929 -11.177 37.378 1.00 19.70 ? 351 LEU A N 1 ATOM 2680 C CA . LEU A 1 351 ? -10.108 -11.615 36.204 1.00 21.28 ? 351 LEU A CA 1 ATOM 2681 C C . LEU A 1 351 ? -8.665 -11.908 36.485 1.00 21.90 ? 351 LEU A C 1 ATOM 2682 O O . LEU A 1 351 ? -7.941 -12.508 35.651 1.00 23.34 ? 351 LEU A O 1 ATOM 2683 C CB . LEU A 1 351 ? -10.243 -10.651 35.011 1.00 19.79 ? 351 LEU A CB 1 ATOM 2684 C CG . LEU A 1 351 ? -11.711 -10.579 34.523 1.00 22.91 ? 351 LEU A CG 1 ATOM 2685 C CD1 . LEU A 1 351 ? -11.928 -9.379 33.619 1.00 22.14 ? 351 LEU A CD1 1 ATOM 2686 C CD2 . LEU A 1 351 ? -12.217 -11.947 33.883 1.00 18.72 ? 351 LEU A CD2 1 ATOM 2687 N N . TYR A 1 352 ? -8.212 -11.431 37.630 1.00 22.84 ? 352 TYR A N 1 ATOM 2688 C CA . TYR A 1 352 ? -6.791 -11.555 37.984 1.00 23.17 ? 352 TYR A CA 1 ATOM 2689 C C . TYR A 1 352 ? -6.662 -12.161 39.377 1.00 23.32 ? 352 TYR A C 1 ATOM 2690 O O . TYR A 1 352 ? -5.710 -11.855 40.123 1.00 22.26 ? 352 TYR A O 1 ATOM 2691 C CB . TYR A 1 352 ? -6.045 -10.227 37.837 1.00 21.42 ? 352 TYR A CB 1 ATOM 2692 C CG . TYR A 1 352 ? -5.963 -9.883 36.410 1.00 22.75 ? 352 TYR A CG 1 ATOM 2693 C CD1 . TYR A 1 352 ? -4.993 -10.474 35.599 1.00 20.92 ? 352 TYR A CD1 1 ATOM 2694 C CD2 . TYR A 1 352 ? -6.896 -8.973 35.819 1.00 18.29 ? 352 TYR A CD2 1 ATOM 2695 C CE1 . TYR A 1 352 ? -4.938 -10.188 34.233 1.00 19.13 ? 352 TYR A CE1 1 ATOM 2696 C CE2 . TYR A 1 352 ? -6.844 -8.695 34.469 1.00 16.33 ? 352 TYR A CE2 1 ATOM 2697 C CZ . TYR A 1 352 ? -5.874 -9.320 33.672 1.00 20.69 ? 352 TYR A CZ 1 ATOM 2698 O OH . TYR A 1 352 ? -5.812 -9.017 32.315 1.00 23.48 ? 352 TYR A OH 1 ATOM 2699 N N . ASN A 1 353 ? -7.646 -13.007 39.700 1.00 23.17 ? 353 ASN A N 1 ATOM 2700 C CA . ASN A 1 353 ? -7.605 -13.772 40.919 1.00 23.82 ? 353 ASN A CA 1 ATOM 2701 C C . ASN A 1 353 ? -6.658 -14.955 40.850 1.00 24.67 ? 353 ASN A C 1 ATOM 2702 O O . ASN A 1 353 ? -6.598 -15.720 41.783 1.00 26.05 ? 353 ASN A O 1 ATOM 2703 C CB . ASN A 1 353 ? -8.988 -14.216 41.340 1.00 22.21 ? 353 ASN A CB 1 ATOM 2704 C CG . ASN A 1 353 ? -9.660 -13.200 42.137 1.00 22.15 ? 353 ASN A CG 1 ATOM 2705 O OD1 . ASN A 1 353 ? -9.284 -12.035 42.115 1.00 21.03 ? 353 ASN A OD1 1 ATOM 2706 N ND2 . ASN A 1 353 ? -10.681 -13.619 42.865 1.00 21.01 ? 353 ASN A ND2 1 ATOM 2707 N N . GLY A 1 354 ? -5.924 -15.115 39.758 1.00 24.94 ? 354 GLY A N 1 ATOM 2708 C CA . GLY A 1 354 ? -4.810 -16.039 39.768 1.00 25.20 ? 354 GLY A CA 1 ATOM 2709 C C . GLY A 1 354 ? -3.509 -15.315 40.097 1.00 25.74 ? 354 GLY A C 1 ATOM 2710 O O . GLY A 1 354 ? -2.477 -15.942 40.156 1.00 26.60 ? 354 GLY A O 1 ATOM 2711 N N . THR A 1 355 ? -3.559 -14.005 40.331 1.00 25.62 ? 355 THR A N 1 ATOM 2712 C CA . THR A 1 355 ? -2.381 -13.183 40.422 1.00 24.95 ? 355 THR A CA 1 ATOM 2713 C C . THR A 1 355 ? -1.999 -12.993 41.904 1.00 26.45 ? 355 THR A C 1 ATOM 2714 O O . THR A 1 355 ? -2.802 -12.492 42.695 1.00 26.34 ? 355 THR A O 1 ATOM 2715 C CB . THR A 1 355 ? -2.625 -11.802 39.730 1.00 25.09 ? 355 THR A CB 1 ATOM 2716 O OG1 . THR A 1 355 ? -2.697 -11.958 38.292 1.00 21.66 ? 355 THR A OG1 1 ATOM 2717 C CG2 . THR A 1 355 ? -1.520 -10.750 40.095 1.00 22.40 ? 355 THR A CG2 1 ATOM 2718 N N . LYS A 1 356 ? -0.766 -13.359 42.270 1.00 27.01 ? 356 LYS A N 1 ATOM 2719 C CA . LYS A 1 356 ? -0.235 -13.037 43.630 1.00 28.36 ? 356 LYS A CA 1 ATOM 2720 C C . LYS A 1 356 ? 0.170 -11.551 43.781 1.00 26.85 ? 356 LYS A C 1 ATOM 2721 O O . LYS A 1 356 ? 0.782 -11.002 42.864 1.00 27.41 ? 356 LYS A O 1 ATOM 2722 C CB . LYS A 1 356 ? 0.918 -13.998 44.000 1.00 28.55 ? 356 LYS A CB 1 ATOM 2723 C CG . LYS A 1 356 ? 0.321 -15.282 44.592 1.00 34.39 ? 356 LYS A CG 1 ATOM 2724 C CD . LYS A 1 356 ? 0.978 -16.620 44.174 1.00 42.30 ? 356 LYS A CD 1 ATOM 2725 C CE . LYS A 1 356 ? -0.102 -17.748 44.331 1.00 46.91 ? 356 LYS A CE 1 ATOM 2726 N NZ . LYS A 1 356 ? 0.361 -19.127 44.774 1.00 49.73 ? 356 LYS A NZ 1 ATOM 2727 N N . PRO A 1 357 ? -0.107 -10.918 44.950 1.00 25.57 ? 357 PRO A N 1 ATOM 2728 C CA . PRO A 1 357 ? 0.246 -9.512 45.166 1.00 25.03 ? 357 PRO A CA 1 ATOM 2729 C C . PRO A 1 357 ? 1.645 -9.235 44.660 1.00 24.92 ? 357 PRO A C 1 ATOM 2730 O O . PRO A 1 357 ? 2.519 -10.073 44.836 1.00 24.80 ? 357 PRO A O 1 ATOM 2731 C CB . PRO A 1 357 ? 0.160 -9.354 46.677 1.00 25.79 ? 357 PRO A CB 1 ATOM 2732 C CG . PRO A 1 357 ? -1.001 -10.271 47.055 1.00 26.77 ? 357 PRO A CG 1 ATOM 2733 C CD . PRO A 1 357 ? -0.794 -11.497 46.116 1.00 26.01 ? 357 PRO A CD 1 ATOM 2734 N N . LEU A 1 358 ? 1.845 -8.118 43.967 1.00 24.34 ? 358 LEU A N 1 ATOM 2735 C CA . LEU A 1 358 ? 3.081 -7.925 43.256 1.00 24.79 ? 358 LEU A CA 1 ATOM 2736 C C . LEU A 1 358 ? 4.110 -7.519 44.272 1.00 26.34 ? 358 LEU A C 1 ATOM 2737 O O . LEU A 1 358 ? 3.810 -6.678 45.162 1.00 26.10 ? 358 LEU A O 1 ATOM 2738 C CB . LEU A 1 358 ? 2.981 -6.840 42.187 1.00 23.62 ? 358 LEU A CB 1 ATOM 2739 C CG . LEU A 1 358 ? 1.951 -6.901 41.045 1.00 24.92 ? 358 LEU A CG 1 ATOM 2740 C CD1 . LEU A 1 358 ? 2.391 -6.028 39.864 1.00 24.71 ? 358 LEU A CD1 1 ATOM 2741 C CD2 . LEU A 1 358 ? 1.577 -8.305 40.630 1.00 22.60 ? 358 LEU A CD2 1 ATOM 2742 N N . SER A 1 359 ? 5.312 -8.096 44.128 1.00 26.77 ? 359 SER A N 1 ATOM 2743 C CA . SER A 1 359 ? 6.481 -7.725 44.946 1.00 27.77 ? 359 SER A CA 1 ATOM 2744 C C . SER A 1 359 ? 6.773 -6.233 44.806 1.00 27.41 ? 359 SER A C 1 ATOM 2745 O O . SER A 1 359 ? 6.875 -5.730 43.703 1.00 28.17 ? 359 SER A O 1 ATOM 2746 C CB . SER A 1 359 ? 7.717 -8.555 44.536 1.00 27.58 ? 359 SER A CB 1 ATOM 2747 O OG . SER A 1 359 ? 8.919 -7.959 45.037 1.00 29.01 ? 359 SER A OG 1 ATOM 2748 N N . THR A 1 360 ? 6.906 -5.530 45.916 1.00 27.58 ? 360 THR A N 1 ATOM 2749 C CA . THR A 1 360 ? 7.275 -4.112 45.888 1.00 29.00 ? 360 THR A CA 1 ATOM 2750 C C . THR A 1 360 ? 8.783 -3.799 45.786 1.00 29.48 ? 360 THR A C 1 ATOM 2751 O O . THR A 1 360 ? 9.172 -2.639 45.717 1.00 30.37 ? 360 THR A O 1 ATOM 2752 C CB . THR A 1 360 ? 6.684 -3.377 47.112 1.00 29.76 ? 360 THR A CB 1 ATOM 2753 O OG1 . THR A 1 360 ? 7.395 -3.797 48.292 1.00 27.98 ? 360 THR A OG1 1 ATOM 2754 C CG2 . THR A 1 360 ? 5.161 -3.736 47.268 1.00 31.04 ? 360 THR A CG2 1 ATOM 2755 N N . THR A 1 361 ? 9.611 -4.828 45.715 1.00 30.99 ? 361 THR A N 1 ATOM 2756 C CA . THR A 1 361 ? 11.080 -4.703 45.805 1.00 32.17 ? 361 THR A CA 1 ATOM 2757 C C . THR A 1 361 ? 11.787 -5.207 44.546 1.00 32.49 ? 361 THR A C 1 ATOM 2758 O O . THR A 1 361 ? 12.863 -4.723 44.176 1.00 31.78 ? 361 THR A O 1 ATOM 2759 C CB . THR A 1 361 ? 11.611 -5.571 46.976 1.00 31.91 ? 361 THR A CB 1 ATOM 2760 O OG1 . THR A 1 361 ? 11.306 -6.958 46.716 1.00 31.39 ? 361 THR A OG1 1 ATOM 2761 C CG2 . THR A 1 361 ? 10.977 -5.142 48.286 1.00 32.56 ? 361 THR A CG2 1 ATOM 2762 N N . THR A 1 362 ? 11.141 -6.186 43.900 1.00 33.62 ? 362 THR A N 1 ATOM 2763 C CA . THR A 1 362 ? 11.696 -6.929 42.772 1.00 34.87 ? 362 THR A CA 1 ATOM 2764 C C . THR A 1 362 ? 10.717 -7.057 41.592 1.00 34.44 ? 362 THR A C 1 ATOM 2765 O O . THR A 1 362 ? 9.506 -7.279 41.785 1.00 34.16 ? 362 THR A O 1 ATOM 2766 C CB . THR A 1 362 ? 12.070 -8.360 43.202 1.00 35.92 ? 362 THR A CB 1 ATOM 2767 O OG1 . THR A 1 362 ? 12.609 -8.334 44.541 1.00 38.57 ? 362 THR A OG1 1 ATOM 2768 C CG2 . THR A 1 362 ? 13.128 -8.940 42.219 1.00 36.50 ? 362 THR A CG2 1 ATOM 2769 N N . VAL A 1 363 ? 11.270 -6.927 40.381 1.00 33.95 ? 363 VAL A N 1 ATOM 2770 C CA . VAL A 1 363 ? 10.560 -7.114 39.137 1.00 33.96 ? 363 VAL A CA 1 ATOM 2771 C C . VAL A 1 363 ? 9.978 -8.527 39.044 1.00 33.80 ? 363 VAL A C 1 ATOM 2772 O O . VAL A 1 363 ? 10.625 -9.523 39.431 1.00 33.14 ? 363 VAL A O 1 ATOM 2773 C CB . VAL A 1 363 ? 11.509 -6.905 37.930 1.00 34.84 ? 363 VAL A CB 1 ATOM 2774 C CG1 . VAL A 1 363 ? 10.862 -7.400 36.665 1.00 36.27 ? 363 VAL A CG1 1 ATOM 2775 C CG2 . VAL A 1 363 ? 11.865 -5.432 37.754 1.00 34.91 ? 363 VAL A CG2 1 ATOM 2776 N N . GLU A 1 364 ? 8.744 -8.595 38.542 1.00 32.97 ? 364 GLU A N 1 ATOM 2777 C CA . GLU A 1 364 ? 8.095 -9.862 38.242 1.00 32.95 ? 364 GLU A CA 1 ATOM 2778 C C . GLU A 1 364 ? 7.628 -9.883 36.775 1.00 32.65 ? 364 GLU A C 1 ATOM 2779 O O . GLU A 1 364 ? 6.818 -9.029 36.335 1.00 33.06 ? 364 GLU A O 1 ATOM 2780 C CB . GLU A 1 364 ? 6.921 -10.136 39.192 1.00 32.42 ? 364 GLU A CB 1 ATOM 2781 C CG . GLU A 1 364 ? 7.297 -10.351 40.659 1.00 33.95 ? 364 GLU A CG 1 ATOM 2782 C CD . GLU A 1 364 ? 6.077 -10.611 41.587 1.00 37.96 ? 364 GLU A CD 1 ATOM 2783 O OE1 . GLU A 1 364 ? 6.265 -11.068 42.741 1.00 40.70 ? 364 GLU A OE1 1 ATOM 2784 O OE2 . GLU A 1 364 ? 4.912 -10.391 41.173 1.00 35.67 ? 364 GLU A OE2 1 ATOM 2785 N N . ASN A 1 365 ? 8.124 -10.869 36.029 1.00 31.82 ? 365 ASN A N 1 ATOM 2786 C CA . ASN A 1 365 ? 7.694 -11.106 34.640 1.00 30.96 ? 365 ASN A CA 1 ATOM 2787 C C . ASN A 1 365 ? 6.198 -11.483 34.515 1.00 31.07 ? 365 ASN A C 1 ATOM 2788 O O . ASN A 1 365 ? 5.501 -11.748 35.517 1.00 30.60 ? 365 ASN A O 1 ATOM 2789 C CB . ASN A 1 365 ? 8.610 -12.137 33.938 1.00 30.17 ? 365 ASN A CB 1 ATOM 2790 C CG . ASN A 1 365 ? 8.482 -13.568 34.525 1.00 30.56 ? 365 ASN A CG 1 ATOM 2791 O OD1 . ASN A 1 365 ? 7.360 -14.069 34.758 1.00 29.87 ? 365 ASN A OD1 1 ATOM 2792 N ND2 . ASN A 1 365 ? 9.639 -14.244 34.745 1.00 29.62 ? 365 ASN A ND2 1 ATOM 2793 N N . ILE A 1 366 ? 5.704 -11.521 33.278 1.00 31.19 ? 366 ILE A N 1 ATOM 2794 C CA . ILE A 1 366 ? 4.274 -11.645 33.054 1.00 30.76 ? 366 ILE A CA 1 ATOM 2795 C C . ILE A 1 366 ? 3.728 -13.044 33.400 1.00 31.05 ? 366 ILE A C 1 ATOM 2796 O O . ILE A 1 366 ? 2.508 -13.208 33.599 1.00 30.76 ? 366 ILE A O 1 ATOM 2797 C CB . ILE A 1 366 ? 3.911 -11.164 31.616 1.00 30.90 ? 366 ILE A CB 1 ATOM 2798 C CG1 . ILE A 1 366 ? 2.419 -10.910 31.466 1.00 30.20 ? 366 ILE A CG1 1 ATOM 2799 C CG2 . ILE A 1 366 ? 4.455 -12.129 30.537 1.00 29.88 ? 366 ILE A CG2 1 ATOM 2800 C CD1 . ILE A 1 366 ? 1.904 -9.632 32.146 1.00 27.21 ? 366 ILE A CD1 1 ATOM 2801 N N . THR A 1 367 ? 4.629 -14.034 33.504 1.00 31.50 ? 367 THR A N 1 ATOM 2802 C CA . THR A 1 367 ? 4.290 -15.391 34.050 1.00 31.55 ? 367 THR A CA 1 ATOM 2803 C C . THR A 1 367 ? 4.051 -15.341 35.567 1.00 31.22 ? 367 THR A C 1 ATOM 2804 O O . THR A 1 367 ? 3.015 -15.824 36.070 1.00 30.51 ? 367 THR A O 1 ATOM 2805 C CB . THR A 1 367 ? 5.388 -16.458 33.720 1.00 32.48 ? 367 THR A CB 1 ATOM 2806 O OG1 . THR A 1 367 ? 5.669 -16.467 32.309 1.00 32.48 ? 367 THR A OG1 1 ATOM 2807 C CG2 . THR A 1 367 ? 4.975 -17.867 34.173 1.00 33.13 ? 367 THR A CG2 1 ATOM 2808 N N . GLN A 1 368 ? 5.002 -14.735 36.293 1.00 30.60 ? 368 GLN A N 1 ATOM 2809 C CA . GLN A 1 368 ? 4.893 -14.602 37.755 1.00 29.75 ? 368 GLN A CA 1 ATOM 2810 C C . GLN A 1 368 ? 3.602 -13.865 38.126 1.00 28.65 ? 368 GLN A C 1 ATOM 2811 O O . GLN A 1 368 ? 2.932 -14.256 39.107 1.00 27.30 ? 368 GLN A O 1 ATOM 2812 C CB . GLN A 1 368 ? 6.119 -13.895 38.343 1.00 30.25 ? 368 GLN A CB 1 ATOM 2813 C CG . GLN A 1 368 ? 7.471 -14.470 37.810 1.00 33.21 ? 368 GLN A CG 1 ATOM 2814 C CD . GLN A 1 368 ? 8.725 -13.819 38.433 1.00 35.23 ? 368 GLN A CD 1 ATOM 2815 O OE1 . GLN A 1 368 ? 9.386 -12.961 37.813 1.00 33.07 ? 368 GLN A OE1 1 ATOM 2816 N NE2 . GLN A 1 368 ? 9.069 -14.255 39.647 1.00 34.21 ? 368 GLN A NE2 1 ATOM 2817 N N . THR A 1 369 ? 3.229 -12.838 37.328 1.00 26.85 ? 369 THR A N 1 ATOM 2818 C CA . THR A 1 369 ? 2.056 -12.038 37.673 1.00 25.55 ? 369 THR A CA 1 ATOM 2819 C C . THR A 1 369 ? 0.776 -12.588 37.050 1.00 25.84 ? 369 THR A C 1 ATOM 2820 O O . THR A 1 369 ? -0.308 -11.978 37.205 1.00 24.98 ? 369 THR A O 1 ATOM 2821 C CB . THR A 1 369 ? 2.166 -10.538 37.362 1.00 25.31 ? 369 THR A CB 1 ATOM 2822 O OG1 . THR A 1 369 ? 2.256 -10.375 35.951 1.00 26.83 ? 369 THR A OG1 1 ATOM 2823 C CG2 . THR A 1 369 ? 3.349 -9.901 38.012 1.00 22.65 ? 369 THR A CG2 1 ATOM 2824 N N . ASP A 1 370 ? 0.910 -13.770 36.417 1.00 25.75 ? 370 ASP A N 1 ATOM 2825 C CA . ASP A 1 370 ? -0.167 -14.515 35.767 1.00 25.63 ? 370 ASP A CA 1 ATOM 2826 C C . ASP A 1 370 ? -1.001 -13.640 34.821 1.00 24.68 ? 370 ASP A C 1 ATOM 2827 O O . ASP A 1 370 ? -2.224 -13.633 34.929 1.00 24.69 ? 370 ASP A O 1 ATOM 2828 C CB . ASP A 1 370 ? -1.057 -15.218 36.806 1.00 25.63 ? 370 ASP A CB 1 ATOM 2829 C CG . ASP A 1 370 ? -2.015 -16.236 36.185 1.00 29.16 ? 370 ASP A CG 1 ATOM 2830 O OD1 . ASP A 1 370 ? -1.603 -16.927 35.226 1.00 32.63 ? 370 ASP A OD1 1 ATOM 2831 O OD2 . ASP A 1 370 ? -3.174 -16.373 36.672 1.00 29.99 ? 370 ASP A OD2 1 ATOM 2832 N N . GLY A 1 371 ? -0.358 -12.901 33.921 1.00 23.75 ? 371 GLY A N 1 ATOM 2833 C CA . GLY A 1 371 ? -1.105 -12.103 32.933 1.00 23.30 ? 371 GLY A CA 1 ATOM 2834 C C . GLY A 1 371 ? -1.402 -10.655 33.319 1.00 24.29 ? 371 GLY A C 1 ATOM 2835 O O . GLY A 1 371 ? -1.797 -9.838 32.458 1.00 24.26 ? 371 GLY A O 1 ATOM 2836 N N . PHE A 1 372 ? -1.161 -10.288 34.584 1.00 22.58 ? 372 PHE A N 1 ATOM 2837 C CA . PHE A 1 372 ? -1.321 -8.874 34.957 1.00 21.87 ? 372 PHE A CA 1 ATOM 2838 C C . PHE A 1 372 ? -0.139 -7.959 34.668 1.00 21.79 ? 372 PHE A C 1 ATOM 2839 O O . PHE A 1 372 ? 0.984 -8.190 35.106 1.00 20.66 ? 372 PHE A O 1 ATOM 2840 C CB . PHE A 1 372 ? -1.727 -8.646 36.429 1.00 20.82 ? 372 PHE A CB 1 ATOM 2841 C CG . PHE A 1 372 ? -1.942 -7.211 36.708 1.00 21.67 ? 372 PHE A CG 1 ATOM 2842 C CD1 . PHE A 1 372 ? -3.063 -6.573 36.179 1.00 19.49 ? 372 PHE A CD1 1 ATOM 2843 C CD2 . PHE A 1 372 ? -0.963 -6.447 37.334 1.00 17.97 ? 372 PHE A CD2 1 ATOM 2844 C CE1 . PHE A 1 372 ? -3.215 -5.242 36.307 1.00 19.40 ? 372 PHE A CE1 1 ATOM 2845 C CE2 . PHE A 1 372 ? -1.138 -5.081 37.500 1.00 17.91 ? 372 PHE A CE2 1 ATOM 2846 C CZ . PHE A 1 372 ? -2.246 -4.476 37.001 1.00 18.92 ? 372 PHE A CZ 1 ATOM 2847 N N . SER A 1 373 ? -0.438 -6.861 33.984 1.00 22.08 ? 373 SER A N 1 ATOM 2848 C CA . SER A 1 373 ? 0.488 -5.733 33.874 1.00 22.20 ? 373 SER A CA 1 ATOM 2849 C C . SER A 1 373 ? -0.293 -4.528 33.357 1.00 21.81 ? 373 SER A C 1 ATOM 2850 O O . SER A 1 373 ? -1.352 -4.689 32.759 1.00 21.61 ? 373 SER A O 1 ATOM 2851 C CB . SER A 1 373 ? 1.669 -6.059 32.961 1.00 22.73 ? 373 SER A CB 1 ATOM 2852 O OG . SER A 1 373 ? 1.359 -5.780 31.618 1.00 22.96 ? 373 SER A OG 1 ATOM 2853 N N . SER A 1 374 ? 0.198 -3.333 33.628 1.00 20.93 ? 374 SER A N 1 ATOM 2854 C CA . SER A 1 374 ? -0.470 -2.153 33.155 1.00 21.90 ? 374 SER A CA 1 ATOM 2855 C C . SER A 1 374 ? -0.595 -2.242 31.658 1.00 21.23 ? 374 SER A C 1 ATOM 2856 O O . SER A 1 374 ? -1.688 -2.083 31.160 1.00 21.25 ? 374 SER A O 1 ATOM 2857 C CB . SER A 1 374 ? 0.284 -0.877 33.494 1.00 21.60 ? 374 SER A CB 1 ATOM 2858 O OG . SER A 1 374 ? -0.091 -0.482 34.776 1.00 26.26 ? 374 SER A OG 1 ATOM 2859 N N . ALA A 1 375 ? 0.542 -2.470 30.985 1.00 20.57 ? 375 ALA A N 1 ATOM 2860 C CA . ALA A 1 375 ? 0.646 -2.559 29.526 1.00 20.49 ? 375 ALA A CA 1 ATOM 2861 C C . ALA A 1 375 ? -0.296 -3.628 28.894 1.00 19.59 ? 375 ALA A C 1 ATOM 2862 O O . ALA A 1 375 ? -0.807 -3.405 27.794 1.00 20.71 ? 375 ALA A O 1 ATOM 2863 C CB . ALA A 1 375 ? 2.161 -2.779 29.076 1.00 19.28 ? 375 ALA A CB 1 ATOM 2864 N N . TRP A 1 376 ? -0.533 -4.731 29.597 1.00 16.81 ? 376 TRP A N 1 ATOM 2865 C CA . TRP A 1 376 ? -1.324 -5.818 29.092 1.00 16.85 ? 376 TRP A CA 1 ATOM 2866 C C . TRP A 1 376 ? -2.823 -5.654 29.348 1.00 17.15 ? 376 TRP A C 1 ATOM 2867 O O . TRP A 1 376 ? -3.598 -6.460 28.833 1.00 17.68 ? 376 TRP A O 1 ATOM 2868 C CB . TRP A 1 376 ? -0.853 -7.155 29.742 1.00 15.94 ? 376 TRP A CB 1 ATOM 2869 C CG . TRP A 1 376 ? 0.289 -7.732 29.033 1.00 14.96 ? 376 TRP A CG 1 ATOM 2870 C CD1 . TRP A 1 376 ? 1.362 -7.046 28.493 1.00 16.45 ? 376 TRP A CD1 1 ATOM 2871 C CD2 . TRP A 1 376 ? 0.492 -9.098 28.713 1.00 12.97 ? 376 TRP A CD2 1 ATOM 2872 N NE1 . TRP A 1 376 ? 2.207 -7.908 27.870 1.00 15.02 ? 376 TRP A NE1 1 ATOM 2873 C CE2 . TRP A 1 376 ? 1.683 -9.175 27.976 1.00 14.31 ? 376 TRP A CE2 1 ATOM 2874 C CE3 . TRP A 1 376 ? -0.232 -10.283 28.977 1.00 13.65 ? 376 TRP A CE3 1 ATOM 2875 C CZ2 . TRP A 1 376 ? 2.195 -10.388 27.521 1.00 15.21 ? 376 TRP A CZ2 1 ATOM 2876 C CZ3 . TRP A 1 376 ? 0.269 -11.472 28.542 1.00 15.34 ? 376 TRP A CZ3 1 ATOM 2877 C CH2 . TRP A 1 376 ? 1.480 -11.521 27.804 1.00 15.31 ? 376 TRP A CH2 1 ATOM 2878 N N . THR A 1 377 ? -3.213 -4.645 30.140 1.00 15.94 ? 377 THR A N 1 ATOM 2879 C CA . THR A 1 377 ? -4.575 -4.468 30.631 1.00 15.46 ? 377 THR A CA 1 ATOM 2880 C C . THR A 1 377 ? -5.124 -3.076 30.251 1.00 15.12 ? 377 THR A C 1 ATOM 2881 O O . THR A 1 377 ? -6.194 -2.967 29.687 1.00 16.42 ? 377 THR A O 1 ATOM 2882 C CB . THR A 1 377 ? -4.663 -4.650 32.175 1.00 15.68 ? 377 THR A CB 1 ATOM 2883 O OG1 . THR A 1 377 ? -3.661 -3.830 32.797 1.00 18.46 ? 377 THR A OG1 1 ATOM 2884 C CG2 . THR A 1 377 ? -4.330 -6.074 32.582 1.00 18.85 ? 377 THR A CG2 1 ATOM 2885 N N . VAL A 1 378 ? -4.413 -2.010 30.570 1.00 15.30 ? 378 VAL A N 1 ATOM 2886 C CA . VAL A 1 378 ? -4.876 -0.672 30.297 1.00 14.99 ? 378 VAL A CA 1 ATOM 2887 C C . VAL A 1 378 ? -3.879 0.199 29.539 1.00 15.56 ? 378 VAL A C 1 ATOM 2888 O O . VAL A 1 378 ? -3.561 1.293 29.986 1.00 16.02 ? 378 VAL A O 1 ATOM 2889 C CB . VAL A 1 378 ? -5.332 0.014 31.618 1.00 16.68 ? 378 VAL A CB 1 ATOM 2890 C CG1 . VAL A 1 378 ? -6.466 -0.758 32.198 1.00 14.86 ? 378 VAL A CG1 1 ATOM 2891 C CG2 . VAL A 1 378 ? -4.192 0.079 32.668 1.00 14.16 ? 378 VAL A CG2 1 ATOM 2892 N N . PRO A 1 379 ? -3.396 -0.272 28.363 1.00 15.97 ? 379 PRO A N 1 ATOM 2893 C CA . PRO A 1 379 ? -2.621 0.620 27.548 1.00 16.83 ? 379 PRO A CA 1 ATOM 2894 C C . PRO A 1 379 ? -3.533 1.678 26.980 1.00 16.80 ? 379 PRO A C 1 ATOM 2895 O O . PRO A 1 379 ? -4.773 1.576 27.141 1.00 17.94 ? 379 PRO A O 1 ATOM 2896 C CB . PRO A 1 379 ? -2.153 -0.296 26.403 1.00 17.48 ? 379 PRO A CB 1 ATOM 2897 C CG . PRO A 1 379 ? -3.300 -1.237 26.268 1.00 16.24 ? 379 PRO A CG 1 ATOM 2898 C CD . PRO A 1 379 ? -3.565 -1.580 27.690 1.00 16.24 ? 379 PRO A CD 1 ATOM 2899 N N . PHE A 1 380 ? -2.953 2.679 26.315 1.00 16.82 ? 380 PHE A N 1 ATOM 2900 C CA . PHE A 1 380 ? -3.761 3.628 25.559 1.00 17.05 ? 380 PHE A CA 1 ATOM 2901 C C . PHE A 1 380 ? -4.652 2.817 24.598 1.00 16.91 ? 380 PHE A C 1 ATOM 2902 O O . PHE A 1 380 ? -4.146 1.896 23.928 1.00 16.84 ? 380 PHE A O 1 ATOM 2903 C CB . PHE A 1 380 ? -2.904 4.593 24.734 1.00 16.62 ? 380 PHE A CB 1 ATOM 2904 C CG . PHE A 1 380 ? -2.205 5.643 25.543 1.00 18.12 ? 380 PHE A CG 1 ATOM 2905 C CD1 . PHE A 1 380 ? -2.926 6.451 26.448 1.00 17.46 ? 380 PHE A CD1 1 ATOM 2906 C CD2 . PHE A 1 380 ? -0.818 5.848 25.377 1.00 15.94 ? 380 PHE A CD2 1 ATOM 2907 C CE1 . PHE A 1 380 ? -2.287 7.445 27.197 1.00 18.96 ? 380 PHE A CE1 1 ATOM 2908 C CE2 . PHE A 1 380 ? -0.186 6.856 26.077 1.00 20.83 ? 380 PHE A CE2 1 ATOM 2909 C CZ . PHE A 1 380 ? -0.918 7.644 27.017 1.00 19.14 ? 380 PHE A CZ 1 ATOM 2910 N N . ALA A 1 381 ? -5.943 3.176 24.548 1.00 16.80 ? 381 ALA A N 1 ATOM 2911 C CA . ALA A 1 381 ? -6.971 2.507 23.741 1.00 16.52 ? 381 ALA A CA 1 ATOM 2912 C C . ALA A 1 381 ? -7.149 1.027 24.114 1.00 16.23 ? 381 ALA A C 1 ATOM 2913 O O . ALA A 1 381 ? -7.476 0.223 23.280 1.00 17.02 ? 381 ALA A O 1 ATOM 2914 C CB . ALA A 1 381 ? -6.640 2.661 22.279 1.00 15.57 ? 381 ALA A CB 1 ATOM 2915 N N . SER A 1 382 ? -6.841 0.639 25.344 1.00 16.48 ? 382 SER A N 1 ATOM 2916 C CA . SER A 1 382 ? -7.157 -0.705 25.809 1.00 16.20 ? 382 SER A CA 1 ATOM 2917 C C . SER A 1 382 ? -8.614 -1.037 25.516 1.00 16.43 ? 382 SER A C 1 ATOM 2918 O O . SER A 1 382 ? -9.504 -0.129 25.459 1.00 17.11 ? 382 SER A O 1 ATOM 2919 C CB . SER A 1 382 ? -7.010 -0.791 27.311 1.00 16.15 ? 382 SER A CB 1 ATOM 2920 O OG . SER A 1 382 ? -7.966 0.059 27.992 1.00 18.76 ? 382 SER A OG 1 ATOM 2921 N N . ARG A 1 383 ? -8.866 -2.334 25.341 1.00 16.88 ? 383 ARG A N 1 ATOM 2922 C CA . ARG A 1 383 ? -10.215 -2.858 25.269 1.00 17.00 ? 383 ARG A CA 1 ATOM 2923 C C . ARG A 1 383 ? -10.342 -4.217 25.999 1.00 17.05 ? 383 ARG A C 1 ATOM 2924 O O . ARG A 1 383 ? -9.401 -5.054 26.017 1.00 15.69 ? 383 ARG A O 1 ATOM 2925 C CB . ARG A 1 383 ? -10.773 -2.879 23.807 1.00 16.83 ? 383 ARG A CB 1 ATOM 2926 C CG . ARG A 1 383 ? -10.117 -3.880 22.805 1.00 16.98 ? 383 ARG A CG 1 ATOM 2927 C CD . ARG A 1 383 ? -8.599 -3.709 22.610 1.00 16.92 ? 383 ARG A CD 1 ATOM 2928 N NE . ARG A 1 383 ? -8.224 -2.407 22.037 1.00 18.09 ? 383 ARG A NE 1 ATOM 2929 C CZ . ARG A 1 383 ? -8.044 -2.166 20.744 1.00 18.06 ? 383 ARG A CZ 1 ATOM 2930 N NH1 . ARG A 1 383 ? -8.260 -3.124 19.831 1.00 20.76 ? 383 ARG A NH1 1 ATOM 2931 N NH2 . ARG A 1 383 ? -7.680 -0.954 20.349 1.00 17.97 ? 383 ARG A NH2 1 ATOM 2932 N N . LEU A 1 384 ? -11.501 -4.347 26.648 1.00 15.18 ? 384 LEU A N 1 ATOM 2933 C CA . LEU A 1 384 ? -11.975 -5.536 27.244 1.00 16.61 ? 384 LEU A CA 1 ATOM 2934 C C . LEU A 1 384 ? -13.281 -5.912 26.481 1.00 16.91 ? 384 LEU A C 1 ATOM 2935 O O . LEU A 1 384 ? -14.175 -5.039 26.324 1.00 17.61 ? 384 LEU A O 1 ATOM 2936 C CB . LEU A 1 384 ? -12.336 -5.214 28.709 1.00 17.59 ? 384 LEU A CB 1 ATOM 2937 C CG . LEU A 1 384 ? -13.182 -6.195 29.529 1.00 19.79 ? 384 LEU A CG 1 ATOM 2938 C CD1 . LEU A 1 384 ? -12.305 -7.413 30.008 1.00 20.18 ? 384 LEU A CD1 1 ATOM 2939 C CD2 . LEU A 1 384 ? -13.971 -5.553 30.693 1.00 19.25 ? 384 LEU A CD2 1 ATOM 2940 N N . TYR A 1 385 ? -13.432 -7.182 26.079 1.00 16.95 ? 385 TYR A N 1 ATOM 2941 C CA . TYR A 1 385 ? -14.697 -7.684 25.475 1.00 17.01 ? 385 TYR A CA 1 ATOM 2942 C C . TYR A 1 385 ? -15.283 -8.757 26.370 1.00 17.50 ? 385 TYR A C 1 ATOM 2943 O O . TYR A 1 385 ? -14.586 -9.728 26.718 1.00 16.58 ? 385 TYR A O 1 ATOM 2944 C CB . TYR A 1 385 ? -14.466 -8.397 24.153 1.00 15.96 ? 385 TYR A CB 1 ATOM 2945 C CG . TYR A 1 385 ? -13.759 -7.628 23.055 1.00 17.73 ? 385 TYR A CG 1 ATOM 2946 C CD1 . TYR A 1 385 ? -13.994 -6.268 22.853 1.00 14.35 ? 385 TYR A CD1 1 ATOM 2947 C CD2 . TYR A 1 385 ? -12.916 -8.280 22.164 1.00 15.53 ? 385 TYR A CD2 1 ATOM 2948 C CE1 . TYR A 1 385 ? -13.357 -5.552 21.827 1.00 14.52 ? 385 TYR A CE1 1 ATOM 2949 C CE2 . TYR A 1 385 ? -12.267 -7.558 21.098 1.00 17.79 ? 385 TYR A CE2 1 ATOM 2950 C CZ . TYR A 1 385 ? -12.514 -6.209 20.941 1.00 17.59 ? 385 TYR A CZ 1 ATOM 2951 O OH . TYR A 1 385 ? -11.892 -5.494 19.933 1.00 17.89 ? 385 TYR A OH 1 ATOM 2952 N N . VAL A 1 386 ? -16.553 -8.590 26.735 1.00 16.52 ? 386 VAL A N 1 ATOM 2953 C CA . VAL A 1 386 ? -17.235 -9.681 27.399 1.00 16.39 ? 386 VAL A CA 1 ATOM 2954 C C . VAL A 1 386 ? -18.238 -10.303 26.375 1.00 17.51 ? 386 VAL A C 1 ATOM 2955 O O . VAL A 1 386 ? -19.062 -9.609 25.749 1.00 17.73 ? 386 VAL A O 1 ATOM 2956 C CB . VAL A 1 386 ? -17.934 -9.187 28.693 1.00 16.47 ? 386 VAL A CB 1 ATOM 2957 C CG1 . VAL A 1 386 ? -18.815 -10.286 29.385 1.00 15.91 ? 386 VAL A CG1 1 ATOM 2958 C CG2 . VAL A 1 386 ? -16.922 -8.577 29.690 1.00 15.56 ? 386 VAL A CG2 1 ATOM 2959 N N . GLU A 1 387 ? -18.116 -11.603 26.176 1.00 17.94 ? 387 GLU A N 1 ATOM 2960 C CA . GLU A 1 387 ? -18.962 -12.343 25.264 1.00 18.40 ? 387 GLU A CA 1 ATOM 2961 C C . GLU A 1 387 ? -19.824 -13.286 26.000 1.00 19.24 ? 387 GLU A C 1 ATOM 2962 O O . GLU A 1 387 ? -19.400 -13.929 26.966 1.00 20.34 ? 387 GLU A O 1 ATOM 2963 C CB . GLU A 1 387 ? -18.121 -13.155 24.304 1.00 17.41 ? 387 GLU A CB 1 ATOM 2964 C CG . GLU A 1 387 ? -17.315 -12.305 23.362 1.00 17.81 ? 387 GLU A CG 1 ATOM 2965 C CD . GLU A 1 387 ? -16.305 -13.112 22.586 1.00 19.93 ? 387 GLU A CD 1 ATOM 2966 O OE1 . GLU A 1 387 ? -15.642 -12.533 21.685 1.00 20.38 ? 387 GLU A OE1 1 ATOM 2967 O OE2 . GLU A 1 387 ? -16.129 -14.314 22.913 1.00 22.48 ? 387 GLU A OE2 1 ATOM 2968 N N . MET A 1 388 ? -21.044 -13.371 25.539 1.00 19.83 ? 388 MET A N 1 ATOM 2969 C CA . MET A 1 388 ? -21.902 -14.466 25.868 1.00 21.52 ? 388 MET A CA 1 ATOM 2970 C C . MET A 1 388 ? -22.139 -15.261 24.561 1.00 22.28 ? 388 MET A C 1 ATOM 2971 O O . MET A 1 388 ? -22.317 -14.668 23.499 1.00 22.42 ? 388 MET A O 1 ATOM 2972 C CB . MET A 1 388 ? -23.180 -13.870 26.450 1.00 21.71 ? 388 MET A CB 1 ATOM 2973 C CG . MET A 1 388 ? -23.889 -14.747 27.353 1.00 25.21 ? 388 MET A CG 1 ATOM 2974 S SD . MET A 1 388 ? -24.734 -13.942 28.709 1.00 28.85 ? 388 MET A SD 1 ATOM 2975 C CE . MET A 1 388 ? -25.984 -12.948 27.920 1.00 27.99 ? 388 MET A CE 1 ATOM 2976 N N . MET A 1 389 ? -22.110 -16.582 24.610 1.00 23.40 ? 389 MET A N 1 ATOM 2977 C CA . MET A 1 389 ? -22.244 -17.406 23.396 1.00 24.40 ? 389 MET A CA 1 ATOM 2978 C C . MET A 1 389 ? -23.095 -18.612 23.680 1.00 26.73 ? 389 MET A C 1 ATOM 2979 O O . MET A 1 389 ? -23.166 -19.069 24.812 1.00 26.51 ? 389 MET A O 1 ATOM 2980 C CB . MET A 1 389 ? -20.872 -17.869 22.861 1.00 22.91 ? 389 MET A CB 1 ATOM 2981 C CG . MET A 1 389 ? -20.174 -18.973 23.686 1.00 19.85 ? 389 MET A CG 1 ATOM 2982 S SD . MET A 1 389 ? -18.520 -19.361 23.043 1.00 23.75 ? 389 MET A SD 1 ATOM 2983 C CE . MET A 1 389 ? -17.631 -17.802 23.068 1.00 23.95 ? 389 MET A CE 1 ATOM 2984 N N . GLN A 1 390 ? -23.754 -19.117 22.644 1.00 30.01 ? 390 GLN A N 1 ATOM 2985 C CA . GLN A 1 390 ? -24.616 -20.285 22.785 1.00 33.62 ? 390 GLN A CA 1 ATOM 2986 C C . GLN A 1 390 ? -23.987 -21.444 22.004 1.00 35.00 ? 390 GLN A C 1 ATOM 2987 O O . GLN A 1 390 ? -23.539 -21.285 20.871 1.00 35.49 ? 390 GLN A O 1 ATOM 2988 C CB . GLN A 1 390 ? -26.003 -19.936 22.305 1.00 34.34 ? 390 GLN A CB 1 ATOM 2989 C CG . GLN A 1 390 ? -27.063 -20.874 22.768 1.00 37.52 ? 390 GLN A CG 1 ATOM 2990 C CD . GLN A 1 390 ? -27.472 -20.700 24.209 1.00 40.76 ? 390 GLN A CD 1 ATOM 2991 O OE1 . GLN A 1 390 ? -27.686 -21.699 24.881 1.00 44.21 ? 390 GLN A OE1 1 ATOM 2992 N NE2 . GLN A 1 390 ? -27.624 -19.447 24.689 1.00 39.68 ? 390 GLN A NE2 1 ATOM 2993 N N . CYS A 1 391 ? -23.848 -22.585 22.654 1.00 37.72 ? 391 CYS A N 1 ATOM 2994 C CA . CYS A 1 391 ? -23.184 -23.720 22.011 1.00 40.63 ? 391 CYS A CA 1 ATOM 2995 C C . CYS A 1 391 ? -24.049 -24.960 21.896 1.00 42.98 ? 391 CYS A C 1 ATOM 2996 O O . CYS A 1 391 ? -25.020 -25.129 22.641 1.00 42.84 ? 391 CYS A O 1 ATOM 2997 C CB . CYS A 1 391 ? -21.848 -24.056 22.686 1.00 40.28 ? 391 CYS A CB 1 ATOM 2998 S SG . CYS A 1 391 ? -20.713 -22.618 22.725 1.00 38.59 ? 391 CYS A SG 1 ATOM 2999 N N . GLN A 1 392 ? -23.662 -25.802 20.925 1.00 46.72 ? 392 GLN A N 1 ATOM 3000 C CA . GLN A 1 392 ? -24.322 -27.070 20.568 1.00 49.37 ? 392 GLN A CA 1 ATOM 3001 C C . GLN A 1 392 ? -24.662 -27.904 21.793 1.00 50.72 ? 392 GLN A C 1 ATOM 3002 O O . GLN A 1 392 ? -25.845 -28.124 22.084 1.00 51.82 ? 392 GLN A O 1 ATOM 3003 C CB . GLN A 1 392 ? -23.437 -27.893 19.609 1.00 49.95 ? 392 GLN A CB 1 ATOM 3004 N N . ALA A 1 393 ? -23.634 -28.323 22.538 1.00 51.71 ? 393 ALA A N 1 ATOM 3005 C CA . ALA A 1 393 ? -23.814 -29.335 23.607 1.00 52.18 ? 393 ALA A CA 1 ATOM 3006 C C . ALA A 1 393 ? -24.372 -28.814 24.964 1.00 52.34 ? 393 ALA A C 1 ATOM 3007 O O . ALA A 1 393 ? -24.560 -29.608 25.916 1.00 52.63 ? 393 ALA A O 1 ATOM 3008 C CB . ALA A 1 393 ? -22.482 -30.149 23.808 1.00 52.40 ? 393 ALA A CB 1 ATOM 3009 N N . GLU A 1 394 ? -24.638 -27.500 25.046 1.00 51.30 ? 394 GLU A N 1 ATOM 3010 C CA . GLU A 1 394 ? -24.945 -26.842 26.323 1.00 50.14 ? 394 GLU A CA 1 ATOM 3011 C C . GLU A 1 394 ? -26.206 -25.964 26.218 1.00 49.18 ? 394 GLU A C 1 ATOM 3012 O O . GLU A 1 394 ? -26.339 -25.139 25.299 1.00 49.16 ? 394 GLU A O 1 ATOM 3013 C CB . GLU A 1 394 ? -23.694 -26.070 26.826 1.00 50.10 ? 394 GLU A CB 1 ATOM 3014 C CG . GLU A 1 394 ? -23.834 -25.212 28.119 1.00 51.48 ? 394 GLU A CG 1 ATOM 3015 C CD . GLU A 1 394 ? -24.008 -25.999 29.455 1.00 54.09 ? 394 GLU A CD 1 ATOM 3016 O OE1 . GLU A 1 394 ? -23.065 -26.733 29.885 1.00 52.82 ? 394 GLU A OE1 1 ATOM 3017 O OE2 . GLU A 1 394 ? -25.089 -25.834 30.096 1.00 54.14 ? 394 GLU A OE2 1 ATOM 3018 N N . GLN A 1 395 ? -27.136 -26.146 27.150 1.00 47.37 ? 395 GLN A N 1 ATOM 3019 C CA . GLN A 1 395 ? -28.364 -25.359 27.127 1.00 45.82 ? 395 GLN A CA 1 ATOM 3020 C C . GLN A 1 395 ? -28.113 -23.920 27.592 1.00 44.27 ? 395 GLN A C 1 ATOM 3021 O O . GLN A 1 395 ? -28.869 -23.002 27.242 1.00 44.42 ? 395 GLN A O 1 ATOM 3022 C CB . GLN A 1 395 ? -29.455 -25.995 27.999 1.00 46.66 ? 395 GLN A CB 1 ATOM 3023 N N . GLU A 1 396 ? -27.056 -23.724 28.378 1.00 40.95 ? 396 GLU A N 1 ATOM 3024 C CA . GLU A 1 396 ? -26.850 -22.435 29.015 1.00 38.50 ? 396 GLU A CA 1 ATOM 3025 C C . GLU A 1 396 ? -25.908 -21.541 28.228 1.00 34.62 ? 396 GLU A C 1 ATOM 3026 O O . GLU A 1 396 ? -25.002 -22.027 27.563 1.00 34.26 ? 396 GLU A O 1 ATOM 3027 C CB . GLU A 1 396 ? -26.313 -22.612 30.431 1.00 39.37 ? 396 GLU A CB 1 ATOM 3028 C CG . GLU A 1 396 ? -27.398 -22.762 31.488 1.00 44.02 ? 396 GLU A CG 1 ATOM 3029 C CD . GLU A 1 396 ? -26.832 -22.550 32.906 1.00 51.12 ? 396 GLU A CD 1 ATOM 3030 O OE1 . GLU A 1 396 ? -26.598 -21.337 33.265 1.00 53.06 ? 396 GLU A OE1 1 ATOM 3031 O OE2 . GLU A 1 396 ? -26.626 -23.593 33.611 1.00 49.04 ? 396 GLU A OE2 1 ATOM 3032 N N . PRO A 1 397 ? -26.113 -20.222 28.323 1.00 30.88 ? 397 PRO A N 1 ATOM 3033 C CA . PRO A 1 397 ? -25.120 -19.371 27.687 1.00 28.31 ? 397 PRO A CA 1 ATOM 3034 C C . PRO A 1 397 ? -23.784 -19.475 28.438 1.00 26.58 ? 397 PRO A C 1 ATOM 3035 O O . PRO A 1 397 ? -23.764 -19.675 29.650 1.00 25.86 ? 397 PRO A O 1 ATOM 3036 C CB . PRO A 1 397 ? -25.729 -17.975 27.770 1.00 27.82 ? 397 PRO A CB 1 ATOM 3037 C CG . PRO A 1 397 ? -27.019 -18.107 28.605 1.00 27.90 ? 397 PRO A CG 1 ATOM 3038 C CD . PRO A 1 397 ? -27.075 -19.475 29.157 1.00 30.32 ? 397 PRO A CD 1 ATOM 3039 N N . LEU A 1 398 ? -22.697 -19.404 27.691 1.00 25.08 ? 398 LEU A N 1 ATOM 3040 C CA . LEU A 1 398 ? -21.351 -19.459 28.188 1.00 23.75 ? 398 LEU A CA 1 ATOM 3041 C C . LEU A 1 398 ? -20.716 -18.047 28.059 1.00 23.99 ? 398 LEU A C 1 ATOM 3042 O O . LEU A 1 398 ? -20.835 -17.385 26.986 1.00 23.79 ? 398 LEU A O 1 ATOM 3043 C CB . LEU A 1 398 ? -20.565 -20.493 27.369 1.00 23.68 ? 398 LEU A CB 1 ATOM 3044 C CG . LEU A 1 398 ? -20.946 -22.002 27.475 1.00 24.90 ? 398 LEU A CG 1 ATOM 3045 C CD1 . LEU A 1 398 ? -19.859 -22.867 26.889 1.00 23.77 ? 398 LEU A CD1 1 ATOM 3046 C CD2 . LEU A 1 398 ? -21.169 -22.427 28.929 1.00 22.24 ? 398 LEU A CD2 1 ATOM 3047 N N . VAL A 1 399 ? -20.067 -17.572 29.139 1.00 22.50 ? 399 VAL A N 1 ATOM 3048 C CA . VAL A 1 399 ? -19.469 -16.231 29.196 1.00 20.19 ? 399 VAL A CA 1 ATOM 3049 C C . VAL A 1 399 ? -17.996 -16.381 28.873 1.00 20.04 ? 399 VAL A C 1 ATOM 3050 O O . VAL A 1 399 ? -17.357 -17.327 29.298 1.00 21.35 ? 399 VAL A O 1 ATOM 3051 C CB . VAL A 1 399 ? -19.567 -15.700 30.599 1.00 19.93 ? 399 VAL A CB 1 ATOM 3052 C CG1 . VAL A 1 399 ? -18.846 -14.419 30.719 1.00 19.23 ? 399 VAL A CG1 1 ATOM 3053 C CG2 . VAL A 1 399 ? -21.016 -15.548 31.007 1.00 18.18 ? 399 VAL A CG2 1 ATOM 3054 N N . ARG A 1 400 ? -17.429 -15.475 28.110 1.00 19.40 ? 400 ARG A N 1 ATOM 3055 C CA . ARG A 1 400 ? -15.993 -15.513 27.836 1.00 17.98 ? 400 ARG A CA 1 ATOM 3056 C C . ARG A 1 400 ? -15.529 -14.080 27.878 1.00 18.62 ? 400 ARG A C 1 ATOM 3057 O O . ARG A 1 400 ? -16.313 -13.159 27.552 1.00 18.07 ? 400 ARG A O 1 ATOM 3058 C CB . ARG A 1 400 ? -15.718 -16.084 26.483 1.00 18.15 ? 400 ARG A CB 1 ATOM 3059 C CG . ARG A 1 400 ? -14.244 -16.086 26.051 1.00 19.90 ? 400 ARG A CG 1 ATOM 3060 C CD . ARG A 1 400 ? -14.032 -16.991 24.810 1.00 24.93 ? 400 ARG A CD 1 ATOM 3061 N NE . ARG A 1 400 ? -14.342 -16.286 23.574 1.00 29.37 ? 400 ARG A NE 1 ATOM 3062 C CZ . ARG A 1 400 ? -13.873 -16.607 22.363 1.00 31.07 ? 400 ARG A CZ 1 ATOM 3063 N NH1 . ARG A 1 400 ? -13.040 -17.639 22.215 1.00 27.16 ? 400 ARG A NH1 1 ATOM 3064 N NH2 . ARG A 1 400 ? -14.226 -15.866 21.284 1.00 28.40 ? 400 ARG A NH2 1 ATOM 3065 N N . VAL A 1 401 ? -14.291 -13.880 28.338 1.00 19.16 ? 401 VAL A N 1 ATOM 3066 C CA . VAL A 1 401 ? -13.736 -12.538 28.480 1.00 19.72 ? 401 VAL A CA 1 ATOM 3067 C C . VAL A 1 401 ? -12.402 -12.402 27.734 1.00 20.16 ? 401 VAL A C 1 ATOM 3068 O O . VAL A 1 401 ? -11.551 -13.281 27.859 1.00 21.32 ? 401 VAL A O 1 ATOM 3069 C CB . VAL A 1 401 ? -13.608 -12.169 29.936 1.00 20.35 ? 401 VAL A CB 1 ATOM 3070 C CG1 . VAL A 1 401 ? -12.714 -10.979 30.082 1.00 20.02 ? 401 VAL A CG1 1 ATOM 3071 C CG2 . VAL A 1 401 ? -14.988 -11.800 30.509 1.00 18.24 ? 401 VAL A CG2 1 ATOM 3072 N N . LEU A 1 402 ? -12.244 -11.360 26.901 1.00 19.02 ? 402 LEU A N 1 ATOM 3073 C CA . LEU A 1 402 ? -10.896 -11.093 26.324 1.00 18.36 ? 402 LEU A CA 1 ATOM 3074 C C . LEU A 1 402 ? -10.352 -9.741 26.770 1.00 18.18 ? 402 LEU A C 1 ATOM 3075 O O . LEU A 1 402 ? -11.086 -8.727 26.722 1.00 19.51 ? 402 LEU A O 1 ATOM 3076 C CB . LEU A 1 402 ? -10.928 -11.146 24.791 1.00 17.37 ? 402 LEU A CB 1 ATOM 3077 C CG . LEU A 1 402 ? -11.399 -12.500 24.194 1.00 17.84 ? 402 LEU A CG 1 ATOM 3078 C CD1 . LEU A 1 402 ? -12.938 -12.629 24.121 1.00 11.42 ? 402 LEU A CD1 1 ATOM 3079 C CD2 . LEU A 1 402 ? -10.835 -12.577 22.781 1.00 18.21 ? 402 LEU A CD2 1 ATOM 3080 N N . VAL A 1 403 ? -9.066 -9.714 27.122 1.00 17.35 ? 403 VAL A N 1 ATOM 3081 C CA . VAL A 1 403 ? -8.359 -8.509 27.524 1.00 16.76 ? 403 VAL A CA 1 ATOM 3082 C C . VAL A 1 403 ? -7.252 -8.204 26.545 1.00 17.57 ? 403 VAL A C 1 ATOM 3083 O O . VAL A 1 403 ? -6.196 -8.880 26.471 1.00 16.54 ? 403 VAL A O 1 ATOM 3084 C CB . VAL A 1 403 ? -7.849 -8.548 29.045 1.00 16.59 ? 403 VAL A CB 1 ATOM 3085 C CG1 . VAL A 1 403 ? -6.984 -7.321 29.390 1.00 16.87 ? 403 VAL A CG1 1 ATOM 3086 C CG2 . VAL A 1 403 ? -9.013 -8.651 29.985 1.00 14.91 ? 403 VAL A CG2 1 ATOM 3087 N N . ASN A 1 404 ? -7.521 -7.170 25.748 1.00 18.15 ? 404 ASN A N 1 ATOM 3088 C CA . ASN A 1 404 ? -6.648 -6.801 24.660 1.00 18.05 ? 404 ASN A CA 1 ATOM 3089 C C . ASN A 1 404 ? -6.319 -7.972 23.721 1.00 17.72 ? 404 ASN A C 1 ATOM 3090 O O . ASN A 1 404 ? -5.189 -8.125 23.239 1.00 17.45 ? 404 ASN A O 1 ATOM 3091 C CB . ASN A 1 404 ? -5.415 -6.062 25.151 1.00 17.69 ? 404 ASN A CB 1 ATOM 3092 C CG . ASN A 1 404 ? -5.766 -4.742 25.884 1.00 19.21 ? 404 ASN A CG 1 ATOM 3093 O OD1 . ASN A 1 404 ? -6.443 -3.833 25.351 1.00 18.58 ? 404 ASN A OD1 1 ATOM 3094 N ND2 . ASN A 1 404 ? -5.356 -4.670 27.117 1.00 22.42 ? 404 ASN A ND2 1 ATOM 3095 N N . ASP A 1 405 ? -7.359 -8.736 23.417 1.00 18.38 ? 405 ASP A N 1 ATOM 3096 C CA . ASP A 1 405 ? -7.312 -9.879 22.478 1.00 20.22 ? 405 ASP A CA 1 ATOM 3097 C C . ASP A 1 405 ? -6.789 -11.154 23.101 1.00 21.94 ? 405 ASP A C 1 ATOM 3098 O O . ASP A 1 405 ? -6.666 -12.170 22.418 1.00 23.54 ? 405 ASP A O 1 ATOM 3099 C CB . ASP A 1 405 ? -6.533 -9.561 21.193 1.00 19.23 ? 405 ASP A CB 1 ATOM 3100 C CG . ASP A 1 405 ? -7.052 -8.320 20.523 1.00 20.77 ? 405 ASP A CG 1 ATOM 3101 O OD1 . ASP A 1 405 ? -8.214 -7.898 20.879 1.00 20.07 ? 405 ASP A OD1 1 ATOM 3102 O OD2 . ASP A 1 405 ? -6.309 -7.737 19.693 1.00 20.51 ? 405 ASP A OD2 1 ATOM 3103 N N . ARG A 1 406 ? -6.490 -11.116 24.394 1.00 23.19 ? 406 ARG A N 1 ATOM 3104 C CA . ARG A 1 406 ? -6.058 -12.322 25.103 1.00 24.03 ? 406 ARG A CA 1 ATOM 3105 C C . ARG A 1 406 ? -7.277 -12.886 25.825 1.00 23.76 ? 406 ARG A C 1 ATOM 3106 O O . ARG A 1 406 ? -7.955 -12.169 26.611 1.00 22.53 ? 406 ARG A O 1 ATOM 3107 C CB . ARG A 1 406 ? -4.918 -11.987 26.083 1.00 24.42 ? 406 ARG A CB 1 ATOM 3108 C CG . ARG A 1 406 ? -4.632 -13.066 27.085 1.00 28.49 ? 406 ARG A CG 1 ATOM 3109 C CD . ARG A 1 406 ? -3.439 -12.759 28.005 1.00 32.69 ? 406 ARG A CD 1 ATOM 3110 N NE . ARG A 1 406 ? -3.071 -13.963 28.755 1.00 35.88 ? 406 ARG A NE 1 ATOM 3111 C CZ . ARG A 1 406 ? -3.362 -14.194 30.035 1.00 39.55 ? 406 ARG A CZ 1 ATOM 3112 N NH1 . ARG A 1 406 ? -3.987 -13.275 30.776 1.00 38.00 ? 406 ARG A NH1 1 ATOM 3113 N NH2 . ARG A 1 406 ? -3.001 -15.357 30.597 1.00 40.72 ? 406 ARG A NH2 1 ATOM 3114 N N . VAL A 1 407 ? -7.596 -14.145 25.527 1.00 23.48 ? 407 VAL A N 1 ATOM 3115 C CA . VAL A 1 407 ? -8.619 -14.850 26.315 1.00 23.13 ? 407 VAL A CA 1 ATOM 3116 C C . VAL A 1 407 ? -8.108 -14.950 27.771 1.00 23.89 ? 407 VAL A C 1 ATOM 3117 O O . VAL A 1 407 ? -6.970 -15.383 27.987 1.00 23.76 ? 407 VAL A O 1 ATOM 3118 C CB . VAL A 1 407 ? -8.911 -16.281 25.814 1.00 22.51 ? 407 VAL A CB 1 ATOM 3119 C CG1 . VAL A 1 407 ? -10.031 -16.893 26.684 1.00 22.56 ? 407 VAL A CG1 1 ATOM 3120 C CG2 . VAL A 1 407 ? -9.357 -16.281 24.342 1.00 21.10 ? 407 VAL A CG2 1 ATOM 3121 N N . VAL A 1 408 ? -8.911 -14.488 28.743 1.00 23.82 ? 408 VAL A N 1 ATOM 3122 C CA . VAL A 1 408 ? -8.537 -14.551 30.173 1.00 22.24 ? 408 VAL A CA 1 ATOM 3123 C C . VAL A 1 408 ? -9.528 -15.439 30.874 1.00 22.57 ? 408 VAL A C 1 ATOM 3124 O O . VAL A 1 408 ? -10.706 -15.067 30.942 1.00 22.69 ? 408 VAL A O 1 ATOM 3125 C CB . VAL A 1 408 ? -8.524 -13.155 30.916 1.00 22.53 ? 408 VAL A CB 1 ATOM 3126 C CG1 . VAL A 1 408 ? -8.298 -13.366 32.464 1.00 21.63 ? 408 VAL A CG1 1 ATOM 3127 C CG2 . VAL A 1 408 ? -7.458 -12.198 30.333 1.00 19.95 ? 408 VAL A CG2 1 ATOM 3128 N N . PRO A 1 409 ? -9.067 -16.608 31.397 1.00 22.40 ? 409 PRO A N 1 ATOM 3129 C CA . PRO A 1 409 ? -9.939 -17.590 32.001 1.00 22.70 ? 409 PRO A CA 1 ATOM 3130 C C . PRO A 1 409 ? -10.678 -17.043 33.206 1.00 23.31 ? 409 PRO A C 1 ATOM 3131 O O . PRO A 1 409 ? -10.083 -16.565 34.123 1.00 24.64 ? 409 PRO A O 1 ATOM 3132 C CB . PRO A 1 409 ? -8.975 -18.693 32.486 1.00 23.03 ? 409 PRO A CB 1 ATOM 3133 C CG . PRO A 1 409 ? -7.777 -18.586 31.630 1.00 23.91 ? 409 PRO A CG 1 ATOM 3134 C CD . PRO A 1 409 ? -7.677 -17.098 31.245 1.00 22.52 ? 409 PRO A CD 1 ATOM 3135 N N . LEU A 1 410 ? -11.983 -17.142 33.231 1.00 22.92 ? 410 LEU A N 1 ATOM 3136 C CA . LEU A 1 410 ? -12.729 -16.654 34.378 1.00 22.65 ? 410 LEU A CA 1 ATOM 3137 C C . LEU A 1 410 ? -12.333 -17.334 35.733 1.00 23.07 ? 410 LEU A C 1 ATOM 3138 O O . LEU A 1 410 ? -11.825 -18.473 35.744 1.00 21.89 ? 410 LEU A O 1 ATOM 3139 C CB . LEU A 1 410 ? -14.218 -16.879 34.099 1.00 22.82 ? 410 LEU A CB 1 ATOM 3140 C CG . LEU A 1 410 ? -14.771 -16.385 32.742 1.00 23.56 ? 410 LEU A CG 1 ATOM 3141 C CD1 . LEU A 1 410 ? -16.307 -16.458 32.754 1.00 20.68 ? 410 LEU A CD1 1 ATOM 3142 C CD2 . LEU A 1 410 ? -14.303 -14.959 32.507 1.00 20.62 ? 410 LEU A CD2 1 ATOM 3143 N N . HIS A 1 411 ? -12.592 -16.619 36.843 1.00 22.21 ? 411 HIS A N 1 ATOM 3144 C CA . HIS A 1 411 ? -12.364 -17.128 38.174 1.00 21.85 ? 411 HIS A CA 1 ATOM 3145 C C . HIS A 1 411 ? -13.689 -17.111 38.954 1.00 22.16 ? 411 HIS A C 1 ATOM 3146 O O . HIS A 1 411 ? -14.631 -16.351 38.638 1.00 20.54 ? 411 HIS A O 1 ATOM 3147 C CB . HIS A 1 411 ? -11.263 -16.335 38.884 1.00 22.41 ? 411 HIS A CB 1 ATOM 3148 C CG . HIS A 1 411 ? -9.866 -16.626 38.402 1.00 23.19 ? 411 HIS A CG 1 ATOM 3149 N ND1 . HIS A 1 411 ? -9.287 -15.965 37.331 1.00 26.81 ? 411 HIS A ND1 1 ATOM 3150 C CD2 . HIS A 1 411 ? -8.909 -17.455 38.881 1.00 21.71 ? 411 HIS A CD2 1 ATOM 3151 C CE1 . HIS A 1 411 ? -8.049 -16.408 37.142 1.00 22.68 ? 411 HIS A CE1 1 ATOM 3152 N NE2 . HIS A 1 411 ? -7.790 -17.302 38.077 1.00 22.19 ? 411 HIS A NE2 1 ATOM 3153 N N . GLY A 1 412 ? -13.794 -17.981 39.953 1.00 21.49 ? 412 GLY A N 1 ATOM 3154 C CA . GLY A 1 412 ? -14.961 -17.938 40.829 1.00 21.32 ? 412 GLY A CA 1 ATOM 3155 C C . GLY A 1 412 ? -16.063 -18.868 40.377 1.00 22.71 ? 412 GLY A C 1 ATOM 3156 O O . GLY A 1 412 ? -17.135 -18.931 41.016 1.00 21.95 ? 412 GLY A O 1 ATOM 3157 N N . CYS A 1 413 ? -15.803 -19.603 39.281 1.00 23.19 ? 413 CYS A N 1 ATOM 3158 C CA . CYS A 1 413 ? -16.825 -20.457 38.639 1.00 24.31 ? 413 CYS A CA 1 ATOM 3159 C C . CYS A 1 413 ? -16.088 -21.610 37.975 1.00 24.72 ? 413 CYS A C 1 ATOM 3160 O O . CYS A 1 413 ? -14.900 -21.499 37.715 1.00 25.06 ? 413 CYS A O 1 ATOM 3161 C CB . CYS A 1 413 ? -17.667 -19.667 37.601 1.00 23.88 ? 413 CYS A CB 1 ATOM 3162 S SG . CYS A 1 413 ? -16.665 -18.759 36.406 1.00 24.34 ? 413 CYS A SG 1 ATOM 3163 N N . PRO A 1 414 ? -16.784 -22.734 37.706 1.00 25.30 ? 414 PRO A N 1 ATOM 3164 C CA . PRO A 1 414 ? -16.040 -23.824 37.050 1.00 25.94 ? 414 PRO A CA 1 ATOM 3165 C C . PRO A 1 414 ? -15.683 -23.498 35.614 1.00 26.58 ? 414 PRO A C 1 ATOM 3166 O O . PRO A 1 414 ? -16.494 -23.740 34.715 1.00 27.72 ? 414 PRO A O 1 ATOM 3167 C CB . PRO A 1 414 ? -17.006 -25.028 37.109 1.00 25.24 ? 414 PRO A CB 1 ATOM 3168 C CG . PRO A 1 414 ? -18.171 -24.561 38.026 1.00 26.06 ? 414 PRO A CG 1 ATOM 3169 C CD . PRO A 1 414 ? -18.199 -23.066 37.937 1.00 24.23 ? 414 PRO A CD 1 ATOM 3170 N N . VAL A 1 415 ? -14.484 -22.969 35.385 1.00 27.78 ? 415 VAL A N 1 ATOM 3171 C CA . VAL A 1 415 ? -14.036 -22.736 34.002 1.00 28.54 ? 415 VAL A CA 1 ATOM 3172 C C . VAL A 1 415 ? -13.714 -23.954 33.243 1.00 28.74 ? 415 VAL A C 1 ATOM 3173 O O . VAL A 1 415 ? -13.111 -24.860 33.776 1.00 30.33 ? 415 VAL A O 1 ATOM 3174 C CB . VAL A 1 415 ? -12.704 -21.958 33.866 1.00 29.98 ? 415 VAL A CB 1 ATOM 3175 C CG1 . VAL A 1 415 ? -12.959 -20.535 33.365 1.00 29.49 ? 415 VAL A CG1 1 ATOM 3176 C CG2 . VAL A 1 415 ? -11.787 -22.080 35.128 1.00 28.61 ? 415 VAL A CG2 1 ATOM 3177 N N . ASP A 1 416 ? -14.037 -23.937 31.955 1.00 29.50 ? 416 ASP A N 1 ATOM 3178 C CA . ASP A 1 416 ? -13.709 -25.022 31.036 1.00 29.03 ? 416 ASP A CA 1 ATOM 3179 C C . ASP A 1 416 ? -12.374 -24.681 30.385 1.00 29.18 ? 416 ASP A C 1 ATOM 3180 O O . ASP A 1 416 ? -11.812 -23.643 30.701 1.00 29.40 ? 416 ASP A O 1 ATOM 3181 C CB . ASP A 1 416 ? -14.872 -25.268 30.040 1.00 29.14 ? 416 ASP A CB 1 ATOM 3182 C CG . ASP A 1 416 ? -15.106 -24.092 29.027 1.00 29.59 ? 416 ASP A CG 1 ATOM 3183 O OD1 . ASP A 1 416 ? -14.156 -23.430 28.563 1.00 26.49 ? 416 ASP A OD1 1 ATOM 3184 O OD2 . ASP A 1 416 ? -16.276 -23.885 28.662 1.00 30.50 ? 416 ASP A OD2 1 ATOM 3185 N N . ALA A 1 417 ? -11.865 -25.525 29.495 1.00 29.53 ? 417 ALA A N 1 ATOM 3186 C CA . ALA A 1 417 ? -10.514 -25.334 28.925 1.00 29.78 ? 417 ALA A CA 1 ATOM 3187 C C . ALA A 1 417 ? -10.530 -24.258 27.879 1.00 30.15 ? 417 ALA A C 1 ATOM 3188 O O . ALA A 1 417 ? -9.473 -23.957 27.244 1.00 30.43 ? 417 ALA A O 1 ATOM 3189 C CB . ALA A 1 417 ? -10.018 -26.639 28.241 1.00 30.41 ? 417 ALA A CB 1 ATOM 3190 N N . LEU A 1 418 ? -11.723 -23.715 27.614 1.00 28.95 ? 418 LEU A N 1 ATOM 3191 C CA . LEU A 1 418 ? -11.771 -22.633 26.642 1.00 28.45 ? 418 LEU A CA 1 ATOM 3192 C C . LEU A 1 418 ? -11.911 -21.268 27.313 1.00 26.95 ? 418 LEU A C 1 ATOM 3193 O O . LEU A 1 418 ? -12.088 -20.284 26.615 1.00 26.81 ? 418 LEU A O 1 ATOM 3194 C CB . LEU A 1 418 ? -12.837 -22.897 25.553 1.00 29.33 ? 418 LEU A CB 1 ATOM 3195 C CG . LEU A 1 418 ? -12.469 -24.052 24.584 1.00 31.50 ? 418 LEU A CG 1 ATOM 3196 C CD1 . LEU A 1 418 ? -13.609 -24.398 23.634 1.00 30.45 ? 418 LEU A CD1 1 ATOM 3197 C CD2 . LEU A 1 418 ? -11.153 -23.809 23.787 1.00 31.43 ? 418 LEU A CD2 1 ATOM 3198 N N . GLY A 1 419 ? -11.822 -21.232 28.654 1.00 25.19 ? 419 GLY A N 1 ATOM 3199 C CA . GLY A 1 419 ? -11.767 -19.986 29.431 1.00 22.69 ? 419 GLY A CA 1 ATOM 3200 C C . GLY A 1 419 ? -13.130 -19.574 29.927 1.00 22.57 ? 419 GLY A C 1 ATOM 3201 O O . GLY A 1 419 ? -13.234 -18.567 30.580 1.00 21.74 ? 419 GLY A O 1 ATOM 3202 N N . ARG A 1 420 ? -14.162 -20.381 29.689 1.00 21.53 ? 420 ARG A N 1 ATOM 3203 C CA . ARG A 1 420 ? -15.530 -19.935 29.853 1.00 22.75 ? 420 ARG A CA 1 ATOM 3204 C C . ARG A 1 420 ? -16.210 -20.551 31.026 1.00 23.11 ? 420 ARG A C 1 ATOM 3205 O O . ARG A 1 420 ? -15.796 -21.608 31.509 1.00 23.72 ? 420 ARG A O 1 ATOM 3206 C CB . ARG A 1 420 ? -16.350 -20.323 28.599 1.00 22.66 ? 420 ARG A CB 1 ATOM 3207 C CG . ARG A 1 420 ? -15.619 -20.078 27.276 1.00 24.66 ? 420 ARG A CG 1 ATOM 3208 C CD . ARG A 1 420 ? -16.409 -20.709 26.075 1.00 26.95 ? 420 ARG A CD 1 ATOM 3209 N NE . ARG A 1 420 ? -16.415 -22.170 26.147 1.00 26.52 ? 420 ARG A NE 1 ATOM 3210 C CZ . ARG A 1 420 ? -16.753 -22.980 25.132 1.00 29.71 ? 420 ARG A CZ 1 ATOM 3211 N NH1 . ARG A 1 420 ? -17.113 -22.465 23.959 1.00 32.66 ? 420 ARG A NH1 1 ATOM 3212 N NH2 . ARG A 1 420 ? -16.698 -24.301 25.268 1.00 25.50 ? 420 ARG A NH2 1 ATOM 3213 N N . CYS A 1 421 ? -17.293 -19.941 31.472 1.00 24.04 ? 421 CYS A N 1 ATOM 3214 C CA . CYS A 1 421 ? -18.151 -20.592 32.508 1.00 25.79 ? 421 CYS A CA 1 ATOM 3215 C C . CYS A 1 421 ? -19.567 -20.362 32.097 1.00 25.70 ? 421 CYS A C 1 ATOM 3216 O O . CYS A 1 421 ? -19.844 -19.402 31.359 1.00 25.51 ? 421 CYS A O 1 ATOM 3217 C CB . CYS A 1 421 ? -18.014 -19.930 33.913 1.00 25.77 ? 421 CYS A CB 1 ATOM 3218 S SG . CYS A 1 421 ? -16.388 -20.035 34.817 1.00 31.79 ? 421 CYS A SG 1 ATOM 3219 N N . THR A 1 422 ? -20.495 -21.143 32.626 1.00 25.06 ? 422 THR A N 1 ATOM 3220 C CA . THR A 1 422 ? -21.851 -20.809 32.319 1.00 25.48 ? 422 THR A CA 1 ATOM 3221 C C . THR A 1 422 ? -22.199 -19.458 32.949 1.00 26.14 ? 422 THR A C 1 ATOM 3222 O O . THR A 1 422 ? -21.684 -19.115 34.006 1.00 27.54 ? 422 THR A O 1 ATOM 3223 C CB . THR A 1 422 ? -22.801 -21.868 32.800 1.00 25.57 ? 422 THR A CB 1 ATOM 3224 O OG1 . THR A 1 422 ? -22.824 -21.828 34.210 1.00 26.00 ? 422 THR A OG1 1 ATOM 3225 C CG2 . THR A 1 422 ? -22.360 -23.288 32.308 1.00 23.52 ? 422 THR A CG2 1 ATOM 3226 N N . ARG A 1 423 ? -23.073 -18.701 32.310 1.00 25.56 ? 423 ARG A N 1 ATOM 3227 C CA . ARG A 1 423 ? -23.573 -17.456 32.848 1.00 26.28 ? 423 ARG A CA 1 ATOM 3228 C C . ARG A 1 423 ? -23.977 -17.541 34.323 1.00 26.44 ? 423 ARG A C 1 ATOM 3229 O O . ARG A 1 423 ? -23.543 -16.717 35.143 1.00 26.58 ? 423 ARG A O 1 ATOM 3230 C CB . ARG A 1 423 ? -24.771 -17.027 31.996 1.00 26.02 ? 423 ARG A CB 1 ATOM 3231 C CG . ARG A 1 423 ? -25.144 -15.584 32.033 1.00 26.84 ? 423 ARG A CG 1 ATOM 3232 C CD . ARG A 1 423 ? -26.457 -15.376 32.718 1.00 32.13 ? 423 ARG A CD 1 ATOM 3233 N NE . ARG A 1 423 ? -27.504 -16.312 32.320 1.00 30.49 ? 423 ARG A NE 1 ATOM 3234 C CZ . ARG A 1 423 ? -28.492 -16.045 31.456 1.00 32.33 ? 423 ARG A CZ 1 ATOM 3235 N NH1 . ARG A 1 423 ? -28.571 -14.872 30.813 1.00 32.04 ? 423 ARG A NH1 1 ATOM 3236 N NH2 . ARG A 1 423 ? -29.399 -16.982 31.200 1.00 29.93 ? 423 ARG A NH2 1 ATOM 3237 N N . ASP A 1 424 ? -24.809 -18.530 34.653 1.00 26.77 ? 424 ASP A N 1 ATOM 3238 C CA . ASP A 1 424 ? -25.395 -18.648 35.993 1.00 27.86 ? 424 ASP A CA 1 ATOM 3239 C C . ASP A 1 424 ? -24.298 -18.858 37.052 1.00 27.09 ? 424 ASP A C 1 ATOM 3240 O O . ASP A 1 424 ? -24.329 -18.213 38.105 1.00 25.71 ? 424 ASP A O 1 ATOM 3241 C CB . ASP A 1 424 ? -26.457 -19.761 36.079 1.00 29.36 ? 424 ASP A CB 1 ATOM 3242 C CG . ASP A 1 424 ? -27.872 -19.332 35.490 1.00 35.26 ? 424 ASP A CG 1 ATOM 3243 O OD1 . ASP A 1 424 ? -28.063 -18.174 34.970 1.00 38.62 ? 424 ASP A OD1 1 ATOM 3244 O OD2 . ASP A 1 424 ? -28.806 -20.191 35.537 1.00 41.37 ? 424 ASP A OD2 1 ATOM 3245 N N . SER A 1 425 ? -23.295 -19.672 36.717 1.00 26.07 ? 425 SER A N 1 ATOM 3246 C CA . SER A 1 425 ? -22.189 -19.911 37.628 1.00 25.79 ? 425 SER A CA 1 ATOM 3247 C C . SER A 1 425 ? -21.222 -18.709 37.666 1.00 25.71 ? 425 SER A C 1 ATOM 3248 O O . SER A 1 425 ? -20.600 -18.464 38.703 1.00 25.98 ? 425 SER A O 1 ATOM 3249 C CB . SER A 1 425 ? -21.401 -21.155 37.238 1.00 24.96 ? 425 SER A CB 1 ATOM 3250 O OG . SER A 1 425 ? -20.523 -20.815 36.179 1.00 24.23 ? 425 SER A OG 1 ATOM 3251 N N . PHE A 1 426 ? -21.062 -17.993 36.547 1.00 24.88 ? 426 PHE A N 1 ATOM 3252 C CA . PHE A 1 426 ? -20.211 -16.806 36.526 1.00 23.84 ? 426 PHE A CA 1 ATOM 3253 C C . PHE A 1 426 ? -20.800 -15.732 37.433 1.00 24.09 ? 426 PHE A C 1 ATOM 3254 O O . PHE A 1 426 ? -20.094 -15.112 38.204 1.00 23.89 ? 426 PHE A O 1 ATOM 3255 C CB . PHE A 1 426 ? -20.061 -16.272 35.101 1.00 24.07 ? 426 PHE A CB 1 ATOM 3256 C CG . PHE A 1 426 ? -19.314 -14.970 35.017 1.00 21.86 ? 426 PHE A CG 1 ATOM 3257 C CD1 . PHE A 1 426 ? -17.949 -14.914 35.293 1.00 22.78 ? 426 PHE A CD1 1 ATOM 3258 C CD2 . PHE A 1 426 ? -19.976 -13.798 34.674 1.00 20.99 ? 426 PHE A CD2 1 ATOM 3259 C CE1 . PHE A 1 426 ? -17.246 -13.707 35.207 1.00 20.42 ? 426 PHE A CE1 1 ATOM 3260 C CE2 . PHE A 1 426 ? -19.284 -12.569 34.614 1.00 18.39 ? 426 PHE A CE2 1 ATOM 3261 C CZ . PHE A 1 426 ? -17.925 -12.527 34.842 1.00 17.83 ? 426 PHE A CZ 1 ATOM 3262 N N . VAL A 1 427 ? -22.108 -15.524 37.328 1.00 24.63 ? 427 VAL A N 1 ATOM 3263 C CA . VAL A 1 427 ? -22.790 -14.524 38.151 1.00 25.00 ? 427 VAL A CA 1 ATOM 3264 C C . VAL A 1 427 ? -22.759 -14.853 39.644 1.00 25.68 ? 427 VAL A C 1 ATOM 3265 O O . VAL A 1 427 ? -22.476 -13.997 40.503 1.00 25.54 ? 427 VAL A O 1 ATOM 3266 C CB . VAL A 1 427 ? -24.208 -14.220 37.638 1.00 25.05 ? 427 VAL A CB 1 ATOM 3267 C CG1 . VAL A 1 427 ? -25.061 -13.415 38.691 1.00 23.64 ? 427 VAL A CG1 1 ATOM 3268 C CG2 . VAL A 1 427 ? -24.091 -13.440 36.310 1.00 21.66 ? 427 VAL A CG2 1 ATOM 3269 N N . ARG A 1 428 ? -23.025 -16.105 39.946 1.00 25.89 ? 428 ARG A N 1 ATOM 3270 C CA . ARG A 1 428 ? -22.875 -16.590 41.292 1.00 26.61 ? 428 ARG A CA 1 ATOM 3271 C C . ARG A 1 428 ? -21.442 -16.375 41.811 1.00 25.22 ? 428 ARG A C 1 ATOM 3272 O O . ARG A 1 428 ? -21.267 -15.867 42.908 1.00 25.24 ? 428 ARG A O 1 ATOM 3273 C CB . ARG A 1 428 ? -23.320 -18.031 41.356 1.00 27.85 ? 428 ARG A CB 1 ATOM 3274 C CG . ARG A 1 428 ? -23.093 -18.725 42.709 1.00 34.01 ? 428 ARG A CG 1 ATOM 3275 C CD . ARG A 1 428 ? -22.547 -20.045 42.334 1.00 40.49 ? 428 ARG A CD 1 ATOM 3276 N NE . ARG A 1 428 ? -22.947 -21.121 43.215 1.00 51.10 ? 428 ARG A NE 1 ATOM 3277 C CZ . ARG A 1 428 ? -23.026 -22.393 42.811 1.00 55.44 ? 428 ARG A CZ 1 ATOM 3278 N NH1 . ARG A 1 428 ? -22.775 -22.691 41.529 1.00 56.54 ? 428 ARG A NH1 1 ATOM 3279 N NH2 . ARG A 1 428 ? -23.378 -23.360 43.669 1.00 55.04 ? 428 ARG A NH2 1 ATOM 3280 N N . GLY A 1 429 ? -20.428 -16.673 41.002 1.00 24.07 ? 429 GLY A N 1 ATOM 3281 C CA . GLY A 1 429 ? -19.047 -16.336 41.360 1.00 23.13 ? 429 GLY A CA 1 ATOM 3282 C C . GLY A 1 429 ? -18.776 -14.884 41.809 1.00 22.89 ? 429 GLY A C 1 ATOM 3283 O O . GLY A 1 429 ? -17.834 -14.625 42.619 1.00 24.04 ? 429 GLY A O 1 ATOM 3284 N N . LEU A 1 430 ? -19.576 -13.937 41.317 1.00 19.93 ? 430 LEU A N 1 ATOM 3285 C CA . LEU A 1 430 ? -19.311 -12.517 41.545 1.00 18.39 ? 430 LEU A CA 1 ATOM 3286 C C . LEU A 1 430 ? -19.999 -12.023 42.800 1.00 18.10 ? 430 LEU A C 1 ATOM 3287 O O . LEU A 1 430 ? -20.517 -10.868 42.844 1.00 17.75 ? 430 LEU A O 1 ATOM 3288 C CB . LEU A 1 430 ? -19.710 -11.656 40.329 1.00 18.59 ? 430 LEU A CB 1 ATOM 3289 C CG . LEU A 1 430 ? -18.956 -11.888 39.005 1.00 17.10 ? 430 LEU A CG 1 ATOM 3290 C CD1 . LEU A 1 430 ? -19.590 -11.022 38.005 1.00 17.29 ? 430 LEU A CD1 1 ATOM 3291 C CD2 . LEU A 1 430 ? -17.435 -11.597 39.078 1.00 13.05 ? 430 LEU A CD2 1 ATOM 3292 N N . SER A 1 431 ? -19.959 -12.887 43.827 1.00 16.24 ? 431 SER A N 1 ATOM 3293 C CA . SER A 1 431 ? -20.501 -12.586 45.136 1.00 16.99 ? 431 SER A CA 1 ATOM 3294 C C . SER A 1 431 ? -19.890 -11.376 45.803 1.00 16.82 ? 431 SER A C 1 ATOM 3295 O O . SER A 1 431 ? -20.587 -10.702 46.563 1.00 17.25 ? 431 SER A O 1 ATOM 3296 C CB . SER A 1 431 ? -20.414 -13.806 46.092 1.00 17.47 ? 431 SER A CB 1 ATOM 3297 O OG . SER A 1 431 ? -19.156 -14.441 46.039 1.00 16.56 ? 431 SER A OG 1 ATOM 3298 N N . PHE A 1 432 ? -18.622 -11.071 45.510 1.00 16.88 ? 432 PHE A N 1 ATOM 3299 C CA . PHE A 1 432 ? -18.002 -9.869 46.060 1.00 17.59 ? 432 PHE A CA 1 ATOM 3300 C C . PHE A 1 432 ? -18.736 -8.650 45.516 1.00 18.57 ? 432 PHE A C 1 ATOM 3301 O O . PHE A 1 432 ? -19.317 -7.834 46.284 1.00 18.58 ? 432 PHE A O 1 ATOM 3302 C CB . PHE A 1 432 ? -16.510 -9.857 45.706 1.00 19.60 ? 432 PHE A CB 1 ATOM 3303 C CG . PHE A 1 432 ? -15.795 -8.558 46.027 1.00 18.81 ? 432 PHE A CG 1 ATOM 3304 C CD1 . PHE A 1 432 ? -15.205 -8.359 47.276 1.00 19.69 ? 432 PHE A CD1 1 ATOM 3305 C CD2 . PHE A 1 432 ? -15.712 -7.562 45.065 1.00 18.57 ? 432 PHE A CD2 1 ATOM 3306 C CE1 . PHE A 1 432 ? -14.544 -7.211 47.573 1.00 16.76 ? 432 PHE A CE1 1 ATOM 3307 C CE2 . PHE A 1 432 ? -15.072 -6.383 45.337 1.00 20.19 ? 432 PHE A CE2 1 ATOM 3308 C CZ . PHE A 1 432 ? -14.490 -6.182 46.608 1.00 21.68 ? 432 PHE A CZ 1 ATOM 3309 N N . ALA A 1 433 ? -18.761 -8.497 44.192 1.00 19.07 ? 433 ALA A N 1 ATOM 3310 C CA . ALA A 1 433 ? -19.614 -7.410 43.618 1.00 18.67 ? 433 ALA A CA 1 ATOM 3311 C C . ALA A 1 433 ? -21.089 -7.560 44.062 1.00 19.35 ? 433 ALA A C 1 ATOM 3312 O O . ALA A 1 433 ? -21.717 -6.582 44.475 1.00 19.31 ? 433 ALA A O 1 ATOM 3313 C CB . ALA A 1 433 ? -19.472 -7.317 42.116 1.00 16.20 ? 433 ALA A CB 1 ATOM 3314 N N . ARG A 1 434 ? -21.655 -8.757 44.063 1.00 21.12 ? 434 ARG A N 1 ATOM 3315 C CA . ARG A 1 434 ? -23.114 -8.791 44.413 1.00 23.50 ? 434 ARG A CA 1 ATOM 3316 C C . ARG A 1 434 ? -23.428 -8.265 45.827 1.00 23.85 ? 434 ARG A C 1 ATOM 3317 O O . ARG A 1 434 ? -24.508 -7.658 46.079 1.00 23.98 ? 434 ARG A O 1 ATOM 3318 C CB . ARG A 1 434 ? -23.793 -10.169 44.163 1.00 23.47 ? 434 ARG A CB 1 ATOM 3319 C CG . ARG A 1 434 ? -23.717 -10.657 42.700 1.00 24.51 ? 434 ARG A CG 1 ATOM 3320 C CD . ARG A 1 434 ? -24.546 -11.918 42.414 1.00 23.03 ? 434 ARG A CD 1 ATOM 3321 N NE . ARG A 1 434 ? -23.830 -13.128 42.867 1.00 25.96 ? 434 ARG A NE 1 ATOM 3322 C CZ . ARG A 1 434 ? -24.128 -13.773 44.003 1.00 25.90 ? 434 ARG A CZ 1 ATOM 3323 N NH1 . ARG A 1 434 ? -25.100 -13.312 44.779 1.00 21.83 ? 434 ARG A NH1 1 ATOM 3324 N NH2 . ARG A 1 434 ? -23.477 -14.877 44.347 1.00 23.12 ? 434 ARG A NH2 1 ATOM 3325 N N . SER A 1 435 ? -22.471 -8.430 46.737 1.00 23.57 ? 435 SER A N 1 ATOM 3326 C CA . SER A 1 435 ? -22.672 -7.987 48.140 1.00 24.12 ? 435 SER A CA 1 ATOM 3327 C C . SER A 1 435 ? -22.331 -6.527 48.356 1.00 23.64 ? 435 SER A C 1 ATOM 3328 O O . SER A 1 435 ? -22.509 -5.974 49.439 1.00 25.17 ? 435 SER A O 1 ATOM 3329 C CB . SER A 1 435 ? -21.923 -8.918 49.119 1.00 24.85 ? 435 SER A CB 1 ATOM 3330 O OG . SER A 1 435 ? -20.552 -9.126 48.741 1.00 25.80 ? 435 SER A OG 1 ATOM 3331 N N . GLY A 1 436 ? -21.911 -5.858 47.292 1.00 23.66 ? 436 GLY A N 1 ATOM 3332 C CA . GLY A 1 436 ? -21.416 -4.469 47.383 1.00 22.94 ? 436 GLY A CA 1 ATOM 3333 C C . GLY A 1 436 ? -19.920 -4.364 47.741 1.00 22.51 ? 436 GLY A C 1 ATOM 3334 O O . GLY A 1 436 ? -19.457 -3.282 48.158 1.00 22.76 ? 436 GLY A O 1 ATOM 3335 N N . GLY A 1 437 ? -19.168 -5.455 47.635 1.00 21.37 ? 437 GLY A N 1 ATOM 3336 C CA . GLY A 1 437 ? -17.756 -5.429 48.033 1.00 22.67 ? 437 GLY A CA 1 ATOM 3337 C C . GLY A 1 437 ? -17.538 -4.685 49.354 1.00 23.09 ? 437 GLY A C 1 ATOM 3338 O O . GLY A 1 437 ? -18.297 -4.863 50.293 1.00 23.86 ? 437 GLY A O 1 ATOM 3339 N N . ASP A 1 438 ? -16.556 -3.797 49.431 1.00 22.94 ? 438 ASP A N 1 ATOM 3340 C CA . ASP A 1 438 ? -16.221 -3.144 50.706 1.00 23.30 ? 438 ASP A CA 1 ATOM 3341 C C . ASP A 1 438 ? -16.650 -1.710 50.673 1.00 23.56 ? 438 ASP A C 1 ATOM 3342 O O . ASP A 1 438 ? -16.029 -0.854 51.303 1.00 23.40 ? 438 ASP A O 1 ATOM 3343 C CB . ASP A 1 438 ? -14.715 -3.266 51.012 1.00 21.98 ? 438 ASP A CB 1 ATOM 3344 C CG . ASP A 1 438 ? -14.279 -4.714 51.076 1.00 22.65 ? 438 ASP A CG 1 ATOM 3345 O OD1 . ASP A 1 438 ? -14.994 -5.480 51.735 1.00 23.11 ? 438 ASP A OD1 1 ATOM 3346 O OD2 . ASP A 1 438 ? -13.283 -5.132 50.443 1.00 22.87 ? 438 ASP A OD2 1 ATOM 3347 N N . TRP A 1 439 ? -17.712 -1.450 49.920 1.00 23.62 ? 439 TRP A N 1 ATOM 3348 C CA . TRP A 1 439 ? -18.173 -0.106 49.759 1.00 23.72 ? 439 TRP A CA 1 ATOM 3349 C C . TRP A 1 439 ? -18.592 0.534 51.112 1.00 25.56 ? 439 TRP A C 1 ATOM 3350 O O . TRP A 1 439 ? -18.452 1.766 51.291 1.00 25.10 ? 439 TRP A O 1 ATOM 3351 C CB . TRP A 1 439 ? -19.313 -0.051 48.725 1.00 23.20 ? 439 TRP A CB 1 ATOM 3352 C CG . TRP A 1 439 ? -19.679 1.362 48.345 1.00 19.00 ? 439 TRP A CG 1 ATOM 3353 C CD1 . TRP A 1 439 ? -20.633 2.125 48.928 1.00 19.80 ? 439 TRP A CD1 1 ATOM 3354 C CD2 . TRP A 1 439 ? -19.042 2.191 47.365 1.00 19.18 ? 439 TRP A CD2 1 ATOM 3355 N NE1 . TRP A 1 439 ? -20.644 3.387 48.376 1.00 20.68 ? 439 TRP A NE1 1 ATOM 3356 C CE2 . TRP A 1 439 ? -19.679 3.455 47.408 1.00 19.68 ? 439 TRP A CE2 1 ATOM 3357 C CE3 . TRP A 1 439 ? -18.022 1.984 46.429 1.00 20.50 ? 439 TRP A CE3 1 ATOM 3358 C CZ2 . TRP A 1 439 ? -19.336 4.501 46.558 1.00 18.28 ? 439 TRP A CZ2 1 ATOM 3359 C CZ3 . TRP A 1 439 ? -17.671 3.049 45.564 1.00 19.93 ? 439 TRP A CZ3 1 ATOM 3360 C CH2 . TRP A 1 439 ? -18.342 4.284 45.642 1.00 18.87 ? 439 TRP A CH2 1 ATOM 3361 N N . ALA A 1 440 ? -19.113 -0.288 52.040 1.00 27.38 ? 440 ALA A N 1 ATOM 3362 C CA . ALA A 1 440 ? -19.486 0.202 53.407 1.00 29.80 ? 440 ALA A CA 1 ATOM 3363 C C . ALA A 1 440 ? -18.282 0.890 54.131 1.00 30.78 ? 440 ALA A C 1 ATOM 3364 O O . ALA A 1 440 ? -18.461 1.850 54.885 1.00 31.27 ? 440 ALA A O 1 ATOM 3365 C CB . ALA A 1 440 ? -20.106 -0.937 54.274 1.00 28.42 ? 440 ALA A CB 1 ATOM 3366 N N . GLU A 1 441 ? -17.064 0.439 53.814 1.00 31.82 ? 441 GLU A N 1 ATOM 3367 C CA . GLU A 1 441 ? -15.840 1.054 54.332 1.00 33.87 ? 441 GLU A CA 1 ATOM 3368 C C . GLU A 1 441 ? -15.408 2.365 53.684 1.00 33.88 ? 441 GLU A C 1 ATOM 3369 O O . GLU A 1 441 ? -14.362 2.907 54.045 1.00 33.86 ? 441 GLU A O 1 ATOM 3370 C CB . GLU A 1 441 ? -14.700 0.036 54.292 1.00 34.55 ? 441 GLU A CB 1 ATOM 3371 C CG . GLU A 1 441 ? -14.960 -1.131 55.271 1.00 38.89 ? 441 GLU A CG 1 ATOM 3372 C CD . GLU A 1 441 ? -14.036 -2.330 55.074 1.00 46.29 ? 441 GLU A CD 1 ATOM 3373 O OE1 . GLU A 1 441 ? -12.937 -2.134 54.486 1.00 46.68 ? 441 GLU A OE1 1 ATOM 3374 O OE2 . GLU A 1 441 ? -14.412 -3.463 55.529 1.00 48.49 ? 441 GLU A OE2 1 ATOM 3375 N N . CYS A 1 442 ? -16.183 2.881 52.733 1.00 33.81 ? 442 CYS A N 1 ATOM 3376 C CA . CYS A 1 442 ? -15.803 4.139 52.071 1.00 34.65 ? 442 CYS A CA 1 ATOM 3377 C C . CYS A 1 442 ? -15.943 5.309 53.034 1.00 36.82 ? 442 CYS A C 1 ATOM 3378 O O . CYS A 1 442 ? -15.428 6.403 52.798 1.00 36.65 ? 442 CYS A O 1 ATOM 3379 C CB . CYS A 1 442 ? -16.654 4.398 50.807 1.00 33.82 ? 442 CYS A CB 1 ATOM 3380 S SG . CYS A 1 442 ? -16.268 3.336 49.361 1.00 28.17 ? 442 CYS A SG 1 ATOM 3381 N N . PHE A 1 443 ? -16.660 5.047 54.124 1.00 40.08 ? 443 PHE A N 1 ATOM 3382 C CA . PHE A 1 443 ? -17.118 6.065 55.060 1.00 42.89 ? 443 PHE A CA 1 ATOM 3383 C C . PHE A 1 443 ? -16.659 5.748 56.515 1.00 45.40 ? 443 PHE A C 1 ATOM 3384 O O . PHE A 1 443 ? -16.252 6.617 57.229 1.00 45.94 ? 443 PHE A O 1 ATOM 3385 C CB . PHE A 1 443 ? -18.627 6.245 54.890 1.00 42.43 ? 443 PHE A CB 1 ATOM 3386 C CG . PHE A 1 443 ? -19.030 6.439 53.457 1.00 42.54 ? 443 PHE A CG 1 ATOM 3387 C CD1 . PHE A 1 443 ? -18.620 7.582 52.759 1.00 42.70 ? 443 PHE A CD1 1 ATOM 3388 C CD2 . PHE A 1 443 ? -19.760 5.454 52.784 1.00 44.35 ? 443 PHE A CD2 1 ATOM 3389 C CE1 . PHE A 1 443 ? -18.934 7.755 51.411 1.00 42.71 ? 443 PHE A CE1 1 ATOM 3390 C CE2 . PHE A 1 443 ? -20.116 5.611 51.424 1.00 45.27 ? 443 PHE A CE2 1 ATOM 3391 C CZ . PHE A 1 443 ? -19.696 6.768 50.735 1.00 45.12 ? 443 PHE A CZ 1 ATOM 3392 N N . ALA A 1 444 ? -16.668 4.498 56.967 1.00 48.37 ? 444 ALA A N 1 ATOM 3393 C CA . ALA A 1 444 ? -15.985 4.222 58.266 1.00 50.68 ? 444 ALA A CA 1 ATOM 3394 C C . ALA A 1 444 ? -14.487 3.836 58.098 1.00 51.54 ? 444 ALA A C 1 ATOM 3395 O O . ALA A 1 444 ? -13.541 4.609 58.414 1.00 52.29 ? 444 ALA A O 1 ATOM 3396 C CB . ALA A 1 444 ? -16.771 3.166 59.141 1.00 51.31 ? 444 ALA A CB 1 ATOM 3397 O OXT . ALA A 1 444 ? -14.189 2.725 57.626 1.00 51.63 ? 444 ALA A OXT 1 ATOM 3398 N N . SER B 1 7 ? 1.340 -18.644 -1.602 1.00 45.71 ? 7 SER B N 1 ATOM 3399 C CA . SER B 1 7 ? 0.997 -17.266 -1.138 1.00 45.51 ? 7 SER B CA 1 ATOM 3400 C C . SER B 1 7 ? 2.120 -16.621 -0.263 1.00 44.55 ? 7 SER B C 1 ATOM 3401 O O . SER B 1 7 ? 2.615 -15.520 -0.604 1.00 45.30 ? 7 SER B O 1 ATOM 3402 C CB . SER B 1 7 ? -0.346 -17.376 -0.400 1.00 46.36 ? 7 SER B CB 1 ATOM 3403 O OG . SER B 1 7 ? -0.868 -16.185 0.097 1.00 48.49 ? 7 SER B OG 1 ATOM 3404 N N . CYS B 1 8 ? 2.535 -17.292 0.827 1.00 41.79 ? 8 CYS B N 1 ATOM 3405 C CA . CYS B 1 8 ? 3.633 -16.796 1.691 1.00 39.94 ? 8 CYS B CA 1 ATOM 3406 C C . CYS B 1 8 ? 5.004 -17.342 1.208 1.00 37.95 ? 8 CYS B C 1 ATOM 3407 O O . CYS B 1 8 ? 6.079 -16.976 1.679 1.00 37.30 ? 8 CYS B O 1 ATOM 3408 C CB . CYS B 1 8 ? 3.379 -17.153 3.166 1.00 39.76 ? 8 CYS B CB 1 ATOM 3409 S SG . CYS B 1 8 ? 3.133 -18.961 3.492 1.00 41.10 ? 8 CYS B SG 1 ATOM 3410 N N . ASP B 1 9 ? 4.933 -18.223 0.243 1.00 35.80 ? 9 ASP B N 1 ATOM 3411 C CA . ASP B 1 9 ? 6.098 -18.801 -0.347 1.00 34.50 ? 9 ASP B CA 1 ATOM 3412 C C . ASP B 1 9 ? 6.054 -18.568 -1.863 1.00 33.76 ? 9 ASP B C 1 ATOM 3413 O O . ASP B 1 9 ? 5.248 -19.199 -2.554 1.00 34.18 ? 9 ASP B O 1 ATOM 3414 C CB . ASP B 1 9 ? 6.088 -20.298 -0.039 1.00 33.69 ? 9 ASP B CB 1 ATOM 3415 C CG . ASP B 1 9 ? 7.297 -21.024 -0.604 1.00 33.06 ? 9 ASP B CG 1 ATOM 3416 O OD1 . ASP B 1 9 ? 8.322 -20.392 -0.903 1.00 32.22 ? 9 ASP B OD1 1 ATOM 3417 O OD2 . ASP B 1 9 ? 7.220 -22.258 -0.699 1.00 34.14 ? 9 ASP B OD2 1 ATOM 3418 N N . THR B 1 10 ? 6.921 -17.697 -2.372 1.00 32.13 ? 10 THR B N 1 ATOM 3419 C CA . THR B 1 10 ? 6.924 -17.309 -3.801 1.00 31.53 ? 10 THR B CA 1 ATOM 3420 C C . THR B 1 10 ? 8.291 -17.389 -4.477 1.00 30.63 ? 10 THR B C 1 ATOM 3421 O O . THR B 1 10 ? 9.310 -17.513 -3.810 1.00 29.76 ? 10 THR B O 1 ATOM 3422 C CB . THR B 1 10 ? 6.441 -15.866 -3.993 1.00 31.40 ? 10 THR B CB 1 ATOM 3423 O OG1 . THR B 1 10 ? 7.358 -14.955 -3.368 1.00 30.94 ? 10 THR B OG1 1 ATOM 3424 C CG2 . THR B 1 10 ? 5.046 -15.682 -3.390 1.00 31.55 ? 10 THR B CG2 1 ATOM 3425 N N . VAL B 1 11 ? 8.307 -17.306 -5.805 1.00 29.45 ? 11 VAL B N 1 ATOM 3426 C CA . VAL B 1 11 ? 9.570 -17.265 -6.548 1.00 29.17 ? 11 VAL B CA 1 ATOM 3427 C C . VAL B 1 11 ? 10.333 -16.053 -6.093 1.00 29.43 ? 11 VAL B C 1 ATOM 3428 O O . VAL B 1 11 ? 11.525 -16.114 -5.867 1.00 29.11 ? 11 VAL B O 1 ATOM 3429 C CB . VAL B 1 11 ? 9.370 -17.209 -8.115 1.00 29.28 ? 11 VAL B CB 1 ATOM 3430 C CG1 . VAL B 1 11 ? 10.658 -16.819 -8.827 1.00 26.91 ? 11 VAL B CG1 1 ATOM 3431 C CG2 . VAL B 1 11 ? 8.841 -18.535 -8.646 1.00 28.46 ? 11 VAL B CG2 1 ATOM 3432 N N . ASP B 1 12 ? 9.629 -14.950 -5.920 1.00 29.91 ? 12 ASP B N 1 ATOM 3433 C CA . ASP B 1 12 ? 10.344 -13.727 -5.752 1.00 31.17 ? 12 ASP B CA 1 ATOM 3434 C C . ASP B 1 12 ? 10.762 -13.400 -4.342 1.00 31.06 ? 12 ASP B C 1 ATOM 3435 O O . ASP B 1 12 ? 11.873 -12.864 -4.121 1.00 29.92 ? 12 ASP B O 1 ATOM 3436 C CB . ASP B 1 12 ? 9.568 -12.571 -6.339 1.00 32.60 ? 12 ASP B CB 1 ATOM 3437 C CG . ASP B 1 12 ? 10.312 -11.933 -7.473 1.00 37.30 ? 12 ASP B CG 1 ATOM 3438 O OD1 . ASP B 1 12 ? 11.275 -11.138 -7.166 1.00 37.11 ? 12 ASP B OD1 1 ATOM 3439 O OD2 . ASP B 1 12 ? 9.934 -12.269 -8.645 1.00 38.77 ? 12 ASP B OD2 1 ATOM 3440 N N . GLN B 1 13 ? 9.875 -13.699 -3.397 1.00 30.20 ? 13 GLN B N 1 ATOM 3441 C CA . GLN B 1 13 ? 10.124 -13.316 -2.037 1.00 30.26 ? 13 GLN B CA 1 ATOM 3442 C C . GLN B 1 13 ? 10.615 -14.474 -1.172 1.00 30.01 ? 13 GLN B C 1 ATOM 3443 O O . GLN B 1 13 ? 11.014 -14.266 -0.044 1.00 30.52 ? 13 GLN B O 1 ATOM 3444 C CB . GLN B 1 13 ? 8.909 -12.608 -1.474 1.00 31.30 ? 13 GLN B CB 1 ATOM 3445 C CG . GLN B 1 13 ? 8.767 -11.187 -1.989 1.00 33.75 ? 13 GLN B CG 1 ATOM 3446 C CD . GLN B 1 13 ? 9.922 -10.328 -1.514 1.00 39.86 ? 13 GLN B CD 1 ATOM 3447 O OE1 . GLN B 1 13 ? 10.003 -10.015 -0.329 1.00 43.82 ? 13 GLN B OE1 1 ATOM 3448 N NE2 . GLN B 1 13 ? 10.827 -9.934 -2.435 1.00 40.15 ? 13 GLN B NE2 1 ATOM 3449 N N . GLY B 1 14 ? 10.626 -15.684 -1.726 1.00 29.16 ? 14 GLY B N 1 ATOM 3450 C CA . GLY B 1 14 ? 11.131 -16.854 -1.056 1.00 28.30 ? 14 GLY B CA 1 ATOM 3451 C C . GLY B 1 14 ? 10.135 -17.261 0.000 1.00 28.83 ? 14 GLY B C 1 ATOM 3452 O O . GLY B 1 14 ? 8.940 -17.068 -0.172 1.00 28.56 ? 14 GLY B O 1 ATOM 3453 N N . TYR B 1 15 ? 10.635 -17.800 1.113 1.00 28.13 ? 15 TYR B N 1 ATOM 3454 C CA . TYR B 1 15 ? 9.789 -18.421 2.116 1.00 28.12 ? 15 TYR B CA 1 ATOM 3455 C C . TYR B 1 15 ? 9.462 -17.451 3.224 1.00 28.98 ? 15 TYR B C 1 ATOM 3456 O O . TYR B 1 15 ? 10.266 -17.215 4.113 1.00 29.62 ? 15 TYR B O 1 ATOM 3457 C CB . TYR B 1 15 ? 10.507 -19.624 2.663 1.00 27.44 ? 15 TYR B CB 1 ATOM 3458 C CG . TYR B 1 15 ? 9.681 -20.464 3.578 1.00 28.14 ? 15 TYR B CG 1 ATOM 3459 C CD1 . TYR B 1 15 ? 8.907 -21.492 3.081 1.00 27.17 ? 15 TYR B CD1 1 ATOM 3460 C CD2 . TYR B 1 15 ? 9.679 -20.234 4.942 1.00 28.23 ? 15 TYR B CD2 1 ATOM 3461 C CE1 . TYR B 1 15 ? 8.161 -22.278 3.908 1.00 27.38 ? 15 TYR B CE1 1 ATOM 3462 C CE2 . TYR B 1 15 ? 8.934 -21.015 5.792 1.00 27.96 ? 15 TYR B CE2 1 ATOM 3463 C CZ . TYR B 1 15 ? 8.184 -22.041 5.280 1.00 28.68 ? 15 TYR B CZ 1 ATOM 3464 O OH . TYR B 1 15 ? 7.431 -22.830 6.133 1.00 27.74 ? 15 TYR B OH 1 ATOM 3465 N N . GLN B 1 16 ? 8.280 -16.855 3.168 1.00 30.52 ? 16 GLN B N 1 ATOM 3466 C CA . GLN B 1 16 ? 7.916 -15.816 4.139 1.00 30.96 ? 16 GLN B CA 1 ATOM 3467 C C . GLN B 1 16 ? 6.852 -16.349 5.080 1.00 32.04 ? 16 GLN B C 1 ATOM 3468 O O . GLN B 1 16 ? 6.191 -15.595 5.780 1.00 32.71 ? 16 GLN B O 1 ATOM 3469 C CB . GLN B 1 16 ? 7.433 -14.547 3.421 1.00 30.83 ? 16 GLN B CB 1 ATOM 3470 C CG . GLN B 1 16 ? 8.445 -13.953 2.431 1.00 30.49 ? 16 GLN B CG 1 ATOM 3471 C CD . GLN B 1 16 ? 9.553 -13.191 3.123 1.00 31.19 ? 16 GLN B CD 1 ATOM 3472 O OE1 . GLN B 1 16 ? 9.521 -12.996 4.354 1.00 31.70 ? 16 GLN B OE1 1 ATOM 3473 N NE2 . GLN B 1 16 ? 10.543 -12.738 2.337 1.00 27.27 ? 16 GLN B NE2 1 ATOM 3474 N N . CYS B 1 17 ? 6.664 -17.659 5.062 1.00 33.33 ? 17 CYS B N 1 ATOM 3475 C CA . CYS B 1 17 ? 5.675 -18.306 5.925 1.00 34.36 ? 17 CYS B CA 1 ATOM 3476 C C . CYS B 1 17 ? 6.274 -18.431 7.315 1.00 34.38 ? 17 CYS B C 1 ATOM 3477 O O . CYS B 1 17 ? 7.462 -18.764 7.434 1.00 34.45 ? 17 CYS B O 1 ATOM 3478 C CB . CYS B 1 17 ? 5.366 -19.692 5.394 1.00 34.64 ? 17 CYS B CB 1 ATOM 3479 S SG . CYS B 1 17 ? 5.003 -19.746 3.641 1.00 39.59 ? 17 CYS B SG 1 ATOM 3480 N N . PHE B 1 18 ? 5.453 -18.171 8.344 1.00 34.36 ? 18 PHE B N 1 ATOM 3481 C CA . PHE B 1 18 ? 5.819 -18.342 9.752 1.00 33.83 ? 18 PHE B CA 1 ATOM 3482 C C . PHE B 1 18 ? 7.165 -17.701 10.042 1.00 33.22 ? 18 PHE B C 1 ATOM 3483 O O . PHE B 1 18 ? 8.040 -18.327 10.659 1.00 33.35 ? 18 PHE B O 1 ATOM 3484 C CB . PHE B 1 18 ? 5.925 -19.820 10.110 1.00 33.59 ? 18 PHE B CB 1 ATOM 3485 C CG . PHE B 1 18 ? 4.818 -20.653 9.566 1.00 35.26 ? 18 PHE B CG 1 ATOM 3486 C CD1 . PHE B 1 18 ? 3.521 -20.583 10.115 1.00 37.68 ? 18 PHE B CD1 1 ATOM 3487 C CD2 . PHE B 1 18 ? 5.053 -21.519 8.509 1.00 34.84 ? 18 PHE B CD2 1 ATOM 3488 C CE1 . PHE B 1 18 ? 2.469 -21.373 9.590 1.00 35.89 ? 18 PHE B CE1 1 ATOM 3489 C CE2 . PHE B 1 18 ? 4.030 -22.301 7.993 1.00 35.05 ? 18 PHE B CE2 1 ATOM 3490 C CZ . PHE B 1 18 ? 2.722 -22.230 8.544 1.00 35.57 ? 18 PHE B CZ 1 ATOM 3491 N N . SER B 1 19 ? 7.331 -16.469 9.591 1.00 32.39 ? 19 SER B N 1 ATOM 3492 C CA . SER B 1 19 ? 8.647 -15.889 9.462 1.00 32.53 ? 19 SER B CA 1 ATOM 3493 C C . SER B 1 19 ? 9.236 -15.536 10.838 1.00 32.29 ? 19 SER B C 1 ATOM 3494 O O . SER B 1 19 ? 10.450 -15.380 10.977 1.00 31.44 ? 19 SER B O 1 ATOM 3495 C CB . SER B 1 19 ? 8.557 -14.657 8.587 1.00 32.32 ? 19 SER B CB 1 ATOM 3496 O OG . SER B 1 19 ? 7.564 -13.830 9.155 1.00 33.74 ? 19 SER B OG 1 ATOM 3497 N N . GLU B 1 20 ? 8.356 -15.398 11.834 1.00 31.72 ? 20 GLU B N 1 ATOM 3498 C CA . GLU B 1 20 ? 8.760 -15.173 13.232 1.00 31.51 ? 20 GLU B CA 1 ATOM 3499 C C . GLU B 1 20 ? 9.582 -16.374 13.788 1.00 29.53 ? 20 GLU B C 1 ATOM 3500 O O . GLU B 1 20 ? 10.390 -16.191 14.663 1.00 29.80 ? 20 GLU B O 1 ATOM 3501 C CB . GLU B 1 20 ? 7.556 -14.788 14.138 1.00 31.81 ? 20 GLU B CB 1 ATOM 3502 C CG . GLU B 1 20 ? 6.425 -15.849 14.244 1.00 35.84 ? 20 GLU B CG 1 ATOM 3503 C CD . GLU B 1 20 ? 5.465 -15.970 12.970 1.00 40.57 ? 20 GLU B CD 1 ATOM 3504 O OE1 . GLU B 1 20 ? 5.288 -14.986 12.188 1.00 38.93 ? 20 GLU B OE1 1 ATOM 3505 O OE2 . GLU B 1 20 ? 4.875 -17.084 12.794 1.00 41.12 ? 20 GLU B OE2 1 ATOM 3506 N N . THR B 1 21 ? 9.412 -17.562 13.219 1.00 27.06 ? 21 THR B N 1 ATOM 3507 C CA . THR B 1 21 ? 10.159 -18.742 13.609 1.00 25.92 ? 21 THR B CA 1 ATOM 3508 C C . THR B 1 21 ? 11.130 -19.185 12.505 1.00 25.09 ? 21 THR B C 1 ATOM 3509 O O . THR B 1 21 ? 12.330 -19.327 12.738 1.00 23.76 ? 21 THR B O 1 ATOM 3510 C CB . THR B 1 21 ? 9.185 -19.870 13.910 1.00 26.10 ? 21 THR B CB 1 ATOM 3511 O OG1 . THR B 1 21 ? 8.313 -19.430 14.964 1.00 28.29 ? 21 THR B OG1 1 ATOM 3512 C CG2 . THR B 1 21 ? 9.920 -21.170 14.359 1.00 26.05 ? 21 THR B CG2 1 ATOM 3513 N N . SER B 1 22 ? 10.603 -19.314 11.287 1.00 23.82 ? 22 SER B N 1 ATOM 3514 C CA . SER B 1 22 ? 11.319 -19.918 10.184 1.00 23.69 ? 22 SER B CA 1 ATOM 3515 C C . SER B 1 22 ? 12.547 -19.094 9.815 1.00 23.01 ? 22 SER B C 1 ATOM 3516 O O . SER B 1 22 ? 13.514 -19.619 9.312 1.00 23.39 ? 22 SER B O 1 ATOM 3517 C CB . SER B 1 22 ? 10.383 -20.051 8.982 1.00 23.32 ? 22 SER B CB 1 ATOM 3518 O OG . SER B 1 22 ? 10.105 -18.764 8.391 1.00 23.14 ? 22 SER B OG 1 ATOM 3519 N N . HIS B 1 23 ? 12.501 -17.797 10.081 1.00 22.98 ? 23 HIS B N 1 ATOM 3520 C CA . HIS B 1 23 ? 13.614 -16.910 9.749 1.00 22.54 ? 23 HIS B CA 1 ATOM 3521 C C . HIS B 1 23 ? 14.776 -16.958 10.723 1.00 22.48 ? 23 HIS B C 1 ATOM 3522 O O . HIS B 1 23 ? 15.816 -16.347 10.473 1.00 23.13 ? 23 HIS B O 1 ATOM 3523 C CB . HIS B 1 23 ? 13.100 -15.490 9.508 1.00 21.82 ? 23 HIS B CB 1 ATOM 3524 C CG . HIS B 1 23 ? 12.328 -15.350 8.230 1.00 24.32 ? 23 HIS B CG 1 ATOM 3525 N ND1 . HIS B 1 23 ? 12.056 -14.127 7.634 1.00 27.97 ? 23 HIS B ND1 1 ATOM 3526 C CD2 . HIS B 1 23 ? 11.766 -16.285 7.429 1.00 24.47 ? 23 HIS B CD2 1 ATOM 3527 C CE1 . HIS B 1 23 ? 11.390 -14.326 6.512 1.00 25.84 ? 23 HIS B CE1 1 ATOM 3528 N NE2 . HIS B 1 23 ? 11.186 -15.627 6.371 1.00 24.90 ? 23 HIS B NE2 1 ATOM 3529 N N . LEU B 1 24 ? 14.639 -17.717 11.815 1.00 22.95 ? 24 LEU B N 1 ATOM 3530 C CA . LEU B 1 24 ? 15.663 -17.734 12.867 1.00 22.56 ? 24 LEU B CA 1 ATOM 3531 C C . LEU B 1 24 ? 16.213 -19.138 12.935 1.00 22.46 ? 24 LEU B C 1 ATOM 3532 O O . LEU B 1 24 ? 16.638 -19.585 13.995 1.00 22.70 ? 24 LEU B O 1 ATOM 3533 C CB . LEU B 1 24 ? 15.081 -17.325 14.231 1.00 22.62 ? 24 LEU B CB 1 ATOM 3534 C CG . LEU B 1 24 ? 14.359 -15.980 14.398 1.00 23.39 ? 24 LEU B CG 1 ATOM 3535 C CD1 . LEU B 1 24 ? 13.607 -15.961 15.747 1.00 27.49 ? 24 LEU B CD1 1 ATOM 3536 C CD2 . LEU B 1 24 ? 15.285 -14.790 14.328 1.00 20.25 ? 24 LEU B CD2 1 ATOM 3537 N N . TRP B 1 25 ? 16.180 -19.869 11.830 1.00 20.90 ? 25 TRP B N 1 ATOM 3538 C CA . TRP B 1 25 ? 16.826 -21.155 11.863 1.00 20.78 ? 25 TRP B CA 1 ATOM 3539 C C . TRP B 1 25 ? 18.263 -21.068 11.350 1.00 19.67 ? 25 TRP B C 1 ATOM 3540 O O . TRP B 1 25 ? 18.855 -22.044 11.011 1.00 19.59 ? 25 TRP B O 1 ATOM 3541 C CB . TRP B 1 25 ? 16.027 -22.183 11.082 1.00 20.35 ? 25 TRP B CB 1 ATOM 3542 C CG . TRP B 1 25 ? 14.673 -22.438 11.627 1.00 23.35 ? 25 TRP B CG 1 ATOM 3543 C CD1 . TRP B 1 25 ? 14.272 -22.334 12.939 1.00 22.07 ? 25 TRP B CD1 1 ATOM 3544 C CD2 . TRP B 1 25 ? 13.513 -22.865 10.884 1.00 24.99 ? 25 TRP B CD2 1 ATOM 3545 N NE1 . TRP B 1 25 ? 12.943 -22.686 13.061 1.00 23.88 ? 25 TRP B NE1 1 ATOM 3546 C CE2 . TRP B 1 25 ? 12.441 -23.001 11.827 1.00 24.58 ? 25 TRP B CE2 1 ATOM 3547 C CE3 . TRP B 1 25 ? 13.263 -23.110 9.513 1.00 21.33 ? 25 TRP B CE3 1 ATOM 3548 C CZ2 . TRP B 1 25 ? 11.139 -23.384 11.445 1.00 25.09 ? 25 TRP B CZ2 1 ATOM 3549 C CZ3 . TRP B 1 25 ? 11.975 -23.507 9.127 1.00 21.72 ? 25 TRP B CZ3 1 ATOM 3550 C CH2 . TRP B 1 25 ? 10.925 -23.655 10.098 1.00 25.65 ? 25 TRP B CH2 1 ATOM 3551 N N . GLY B 1 26 ? 18.812 -19.877 11.261 1.00 20.12 ? 26 GLY B N 1 ATOM 3552 C CA . GLY B 1 26 ? 20.139 -19.746 10.646 1.00 20.81 ? 26 GLY B CA 1 ATOM 3553 C C . GLY B 1 26 ? 20.243 -20.376 9.246 1.00 20.67 ? 26 GLY B C 1 ATOM 3554 O O . GLY B 1 26 ? 19.362 -20.144 8.397 1.00 20.84 ? 26 GLY B O 1 ATOM 3555 N N . GLN B 1 27 ? 21.314 -21.143 9.026 1.00 19.11 ? 27 GLN B N 1 ATOM 3556 C CA . GLN B 1 27 ? 21.595 -21.802 7.769 1.00 18.96 ? 27 GLN B CA 1 ATOM 3557 C C . GLN B 1 27 ? 20.640 -22.949 7.501 1.00 19.11 ? 27 GLN B C 1 ATOM 3558 O O . GLN B 1 27 ? 20.755 -23.637 6.452 1.00 19.67 ? 27 GLN B O 1 ATOM 3559 C CB . GLN B 1 27 ? 23.050 -22.285 7.703 1.00 19.22 ? 27 GLN B CB 1 ATOM 3560 C CG . GLN B 1 27 ? 23.389 -23.541 8.488 1.00 20.22 ? 27 GLN B CG 1 ATOM 3561 C CD . GLN B 1 27 ? 23.446 -23.329 10.032 1.00 24.04 ? 27 GLN B CD 1 ATOM 3562 O OE1 . GLN B 1 27 ? 23.717 -22.226 10.544 1.00 20.89 ? 27 GLN B OE1 1 ATOM 3563 N NE2 . GLN B 1 27 ? 23.238 -24.420 10.761 1.00 23.88 ? 27 GLN B NE2 1 ATOM 3564 N N . TYR B 1 28 ? 19.756 -23.203 8.458 1.00 18.03 ? 28 TYR B N 1 ATOM 3565 C CA . TYR B 1 28 ? 18.619 -24.054 8.210 1.00 19.88 ? 28 TYR B CA 1 ATOM 3566 C C . TYR B 1 28 ? 17.342 -23.279 7.858 1.00 20.21 ? 28 TYR B C 1 ATOM 3567 O O . TYR B 1 28 ? 16.287 -23.878 7.753 1.00 21.36 ? 28 TYR B O 1 ATOM 3568 C CB . TYR B 1 28 ? 18.331 -25.021 9.394 1.00 20.15 ? 28 TYR B CB 1 ATOM 3569 C CG . TYR B 1 28 ? 19.512 -25.887 9.824 1.00 20.82 ? 28 TYR B CG 1 ATOM 3570 C CD1 . TYR B 1 28 ? 20.418 -26.412 8.885 1.00 20.59 ? 28 TYR B CD1 1 ATOM 3571 C CD2 . TYR B 1 28 ? 19.732 -26.176 11.166 1.00 21.61 ? 28 TYR B CD2 1 ATOM 3572 C CE1 . TYR B 1 28 ? 21.498 -27.216 9.266 1.00 18.57 ? 28 TYR B CE1 1 ATOM 3573 C CE2 . TYR B 1 28 ? 20.833 -26.971 11.576 1.00 20.62 ? 28 TYR B CE2 1 ATOM 3574 C CZ . TYR B 1 28 ? 21.709 -27.464 10.642 1.00 20.74 ? 28 TYR B CZ 1 ATOM 3575 O OH . TYR B 1 28 ? 22.771 -28.239 11.049 1.00 21.49 ? 28 TYR B OH 1 ATOM 3576 N N . ALA B 1 29 ? 17.426 -21.953 7.728 1.00 21.11 ? 29 ALA B N 1 ATOM 3577 C CA . ALA B 1 29 ? 16.334 -21.159 7.214 1.00 22.21 ? 29 ALA B CA 1 ATOM 3578 C C . ALA B 1 29 ? 16.193 -21.393 5.698 1.00 22.24 ? 29 ALA B C 1 ATOM 3579 O O . ALA B 1 29 ? 17.200 -21.456 4.948 1.00 22.24 ? 29 ALA B O 1 ATOM 3580 C CB . ALA B 1 29 ? 16.544 -19.675 7.509 1.00 22.35 ? 29 ALA B CB 1 ATOM 3581 N N . PRO B 1 30 ? 14.961 -21.566 5.249 1.00 21.96 ? 30 PRO B N 1 ATOM 3582 C CA . PRO B 1 30 ? 14.758 -21.626 3.792 1.00 21.38 ? 30 PRO B CA 1 ATOM 3583 C C . PRO B 1 30 ? 15.001 -20.215 3.278 1.00 20.25 ? 30 PRO B C 1 ATOM 3584 O O . PRO B 1 30 ? 14.675 -19.241 4.007 1.00 19.90 ? 30 PRO B O 1 ATOM 3585 C CB . PRO B 1 30 ? 13.290 -21.995 3.642 1.00 21.10 ? 30 PRO B CB 1 ATOM 3586 C CG . PRO B 1 30 ? 12.774 -22.338 5.042 1.00 23.20 ? 30 PRO B CG 1 ATOM 3587 C CD . PRO B 1 30 ? 13.693 -21.587 6.007 1.00 23.04 ? 30 PRO B CD 1 ATOM 3588 N N . PHE B 1 31 ? 15.651 -20.093 2.123 1.00 18.78 ? 31 PHE B N 1 ATOM 3589 C CA . PHE B 1 31 ? 15.815 -18.760 1.505 1.00 18.40 ? 31 PHE B CA 1 ATOM 3590 C C . PHE B 1 31 ? 14.572 -17.869 1.695 1.00 18.22 ? 31 PHE B C 1 ATOM 3591 O O . PHE B 1 31 ? 13.418 -18.323 1.451 1.00 16.75 ? 31 PHE B O 1 ATOM 3592 C CB . PHE B 1 31 ? 16.143 -18.824 0.005 1.00 18.75 ? 31 PHE B CB 1 ATOM 3593 C CG . PHE B 1 31 ? 15.971 -17.491 -0.681 1.00 18.86 ? 31 PHE B CG 1 ATOM 3594 C CD1 . PHE B 1 31 ? 16.880 -16.468 -0.455 1.00 19.68 ? 31 PHE B CD1 1 ATOM 3595 C CD2 . PHE B 1 31 ? 14.864 -17.221 -1.460 1.00 19.41 ? 31 PHE B CD2 1 ATOM 3596 C CE1 . PHE B 1 31 ? 16.709 -15.223 -1.025 1.00 19.92 ? 31 PHE B CE1 1 ATOM 3597 C CE2 . PHE B 1 31 ? 14.693 -15.967 -2.025 1.00 18.20 ? 31 PHE B CE2 1 ATOM 3598 C CZ . PHE B 1 31 ? 15.616 -14.975 -1.799 1.00 19.09 ? 31 PHE B CZ 1 ATOM 3599 N N . PHE B 1 32 ? 14.810 -16.632 2.125 1.00 17.89 ? 32 PHE B N 1 ATOM 3600 C CA . PHE B 1 32 ? 13.746 -15.602 2.174 1.00 20.08 ? 32 PHE B CA 1 ATOM 3601 C C . PHE B 1 32 ? 14.410 -14.310 1.724 1.00 20.26 ? 32 PHE B C 1 ATOM 3602 O O . PHE B 1 32 ? 15.589 -14.052 2.087 1.00 20.99 ? 32 PHE B O 1 ATOM 3603 C CB . PHE B 1 32 ? 13.120 -15.458 3.576 1.00 20.49 ? 32 PHE B CB 1 ATOM 3604 C CG . PHE B 1 32 ? 14.122 -15.141 4.682 1.00 22.75 ? 32 PHE B CG 1 ATOM 3605 C CD1 . PHE B 1 32 ? 14.896 -16.161 5.252 1.00 25.26 ? 32 PHE B CD1 1 ATOM 3606 C CD2 . PHE B 1 32 ? 14.275 -13.848 5.158 1.00 24.93 ? 32 PHE B CD2 1 ATOM 3607 C CE1 . PHE B 1 32 ? 15.818 -15.904 6.258 1.00 25.81 ? 32 PHE B CE1 1 ATOM 3608 C CE2 . PHE B 1 32 ? 15.182 -13.578 6.201 1.00 26.82 ? 32 PHE B CE2 1 ATOM 3609 C CZ . PHE B 1 32 ? 15.975 -14.616 6.727 1.00 26.59 ? 32 PHE B CZ 1 ATOM 3610 N N . SER B 1 33 ? 13.699 -13.525 0.911 1.00 20.31 ? 33 SER B N 1 ATOM 3611 C CA . SER B 1 33 ? 14.274 -12.345 0.271 1.00 19.04 ? 33 SER B CA 1 ATOM 3612 C C . SER B 1 33 ? 14.393 -11.227 1.258 1.00 20.14 ? 33 SER B C 1 ATOM 3613 O O . SER B 1 33 ? 13.477 -10.967 2.076 1.00 19.86 ? 33 SER B O 1 ATOM 3614 C CB . SER B 1 33 ? 13.399 -11.881 -0.879 1.00 18.66 ? 33 SER B CB 1 ATOM 3615 O OG . SER B 1 33 ? 13.964 -10.707 -1.475 1.00 18.43 ? 33 SER B OG 1 ATOM 3616 N N . LEU B 1 34 ? 15.520 -10.555 1.181 1.00 20.54 ? 34 LEU B N 1 ATOM 3617 C CA . LEU B 1 34 ? 15.791 -9.438 2.079 1.00 22.56 ? 34 LEU B CA 1 ATOM 3618 C C . LEU B 1 34 ? 15.635 -8.106 1.351 1.00 23.55 ? 34 LEU B C 1 ATOM 3619 O O . LEU B 1 34 ? 16.141 -7.080 1.813 1.00 23.08 ? 34 LEU B O 1 ATOM 3620 C CB . LEU B 1 34 ? 17.215 -9.538 2.616 1.00 21.41 ? 34 LEU B CB 1 ATOM 3621 C CG . LEU B 1 34 ? 17.334 -10.736 3.551 1.00 23.16 ? 34 LEU B CG 1 ATOM 3622 C CD1 . LEU B 1 34 ? 18.790 -10.944 3.847 1.00 20.62 ? 34 LEU B CD1 1 ATOM 3623 C CD2 . LEU B 1 34 ? 16.491 -10.476 4.812 1.00 22.01 ? 34 LEU B CD2 1 ATOM 3624 N N . ALA B 1 35 ? 14.974 -8.149 0.192 1.00 25.96 ? 35 ALA B N 1 ATOM 3625 C CA . ALA B 1 35 ? 14.856 -6.953 -0.671 1.00 28.32 ? 35 ALA B CA 1 ATOM 3626 C C . ALA B 1 35 ? 14.267 -5.776 0.093 1.00 29.58 ? 35 ALA B C 1 ATOM 3627 O O . ALA B 1 35 ? 14.732 -4.663 -0.045 1.00 30.11 ? 35 ALA B O 1 ATOM 3628 C CB . ALA B 1 35 ? 14.008 -7.255 -1.907 1.00 27.75 ? 35 ALA B CB 1 ATOM 3629 N N . ASN B 1 36 ? 13.264 -6.071 0.917 1.00 31.52 ? 36 ASN B N 1 ATOM 3630 C CA A ASN B 1 36 ? 12.531 -5.012 1.587 0.50 32.80 ? 36 ASN B CA 1 ATOM 3631 C CA B ASN B 1 36 ? 12.471 -5.109 1.694 0.50 33.17 ? 36 ASN B CA 1 ATOM 3632 C C . ASN B 1 36 ? 13.204 -4.562 2.893 1.00 33.60 ? 36 ASN B C 1 ATOM 3633 O O . ASN B 1 36 ? 12.729 -3.634 3.527 1.00 33.87 ? 36 ASN B O 1 ATOM 3634 C CB A ASN B 1 36 ? 11.036 -5.393 1.720 0.50 32.75 ? 36 ASN B CB 1 ATOM 3635 C CB B ASN B 1 36 ? 11.164 -5.766 2.194 0.50 33.25 ? 36 ASN B CB 1 ATOM 3636 C CG A ASN B 1 36 ? 10.363 -5.611 0.337 0.50 32.92 ? 36 ASN B CG 1 ATOM 3637 C CG B ASN B 1 36 ? 11.335 -6.497 3.533 0.50 35.04 ? 36 ASN B CG 1 ATOM 3638 O OD1 A ASN B 1 36 ? 10.502 -4.782 -0.566 0.50 33.78 ? 36 ASN B OD1 1 ATOM 3639 O OD1 B ASN B 1 36 ? 12.211 -7.356 3.688 0.50 33.81 ? 36 ASN B OD1 1 ATOM 3640 N ND2 A ASN B 1 36 ? 9.671 -6.734 0.172 0.50 31.15 ? 36 ASN B ND2 1 ATOM 3641 N ND2 B ASN B 1 36 ? 10.480 -6.157 4.505 0.50 37.19 ? 36 ASN B ND2 1 ATOM 3642 N N . GLU B 1 37 ? 14.336 -5.209 3.225 1.00 35.03 ? 37 GLU B N 1 ATOM 3643 C CA . GLU B 1 37 ? 15.226 -4.841 4.338 1.00 35.90 ? 37 GLU B CA 1 ATOM 3644 C C . GLU B 1 37 ? 16.480 -4.156 3.813 1.00 36.33 ? 37 GLU B C 1 ATOM 3645 O O . GLU B 1 37 ? 17.346 -3.750 4.607 1.00 36.36 ? 37 GLU B O 1 ATOM 3646 C CB . GLU B 1 37 ? 15.648 -6.073 5.149 1.00 36.36 ? 37 GLU B CB 1 ATOM 3647 C CG . GLU B 1 37 ? 14.501 -6.884 5.804 1.00 38.19 ? 37 GLU B CG 1 ATOM 3648 C CD . GLU B 1 37 ? 14.143 -6.418 7.225 1.00 43.42 ? 37 GLU B CD 1 ATOM 3649 O OE1 . GLU B 1 37 ? 14.454 -5.257 7.608 1.00 45.20 ? 37 GLU B OE1 1 ATOM 3650 O OE2 . GLU B 1 37 ? 13.565 -7.240 7.989 1.00 45.44 ? 37 GLU B OE2 1 ATOM 3651 N N . SER B 1 38 ? 16.588 -4.035 2.484 1.00 35.97 ? 38 SER B N 1 ATOM 3652 C CA . SER B 1 38 ? 17.676 -3.258 1.853 1.00 35.80 ? 38 SER B CA 1 ATOM 3653 C C . SER B 1 38 ? 17.448 -1.751 1.946 1.00 36.39 ? 38 SER B C 1 ATOM 3654 O O . SER B 1 38 ? 16.438 -1.234 1.471 1.00 37.25 ? 38 SER B O 1 ATOM 3655 C CB . SER B 1 38 ? 17.789 -3.640 0.380 1.00 35.68 ? 38 SER B CB 1 ATOM 3656 O OG . SER B 1 38 ? 19.058 -3.327 -0.123 1.00 32.80 ? 38 SER B OG 1 ATOM 3657 N N . VAL B 1 39 ? 18.390 -1.026 2.525 1.00 36.67 ? 39 VAL B N 1 ATOM 3658 C CA . VAL B 1 39 ? 18.249 0.428 2.623 1.00 36.85 ? 39 VAL B CA 1 ATOM 3659 C C . VAL B 1 39 ? 18.474 1.051 1.278 1.00 36.63 ? 39 VAL B C 1 ATOM 3660 O O . VAL B 1 39 ? 17.853 2.070 0.940 1.00 37.63 ? 39 VAL B O 1 ATOM 3661 C CB . VAL B 1 39 ? 19.203 1.034 3.703 1.00 37.28 ? 39 VAL B CB 1 ATOM 3662 C CG1 . VAL B 1 39 ? 19.185 2.575 3.691 1.00 37.52 ? 39 VAL B CG1 1 ATOM 3663 C CG2 . VAL B 1 39 ? 18.790 0.510 5.075 1.00 39.17 ? 39 VAL B CG2 1 ATOM 3664 N N . ILE B 1 40 ? 19.391 0.456 0.522 1.00 35.69 ? 40 ILE B N 1 ATOM 3665 C CA . ILE B 1 40 ? 19.667 0.867 -0.835 1.00 34.74 ? 40 ILE B CA 1 ATOM 3666 C C . ILE B 1 40 ? 18.776 0.030 -1.792 1.00 35.52 ? 40 ILE B C 1 ATOM 3667 O O . ILE B 1 40 ? 18.548 -1.169 -1.596 1.00 35.04 ? 40 ILE B O 1 ATOM 3668 C CB . ILE B 1 40 ? 21.196 0.740 -1.139 1.00 34.30 ? 40 ILE B CB 1 ATOM 3669 C CG1 . ILE B 1 40 ? 22.025 1.577 -0.137 1.00 32.42 ? 40 ILE B CG1 1 ATOM 3670 C CG2 . ILE B 1 40 ? 21.520 1.088 -2.602 1.00 32.80 ? 40 ILE B CG2 1 ATOM 3671 C CD1 . ILE B 1 40 ? 23.527 1.218 -0.097 1.00 29.59 ? 40 ILE B CD1 1 ATOM 3672 N N . SER B 1 41 ? 18.253 0.679 -2.814 1.00 35.97 ? 41 SER B N 1 ATOM 3673 C CA . SER B 1 41 ? 17.354 0.020 -3.739 1.00 37.28 ? 41 SER B CA 1 ATOM 3674 C C . SER B 1 41 ? 18.118 -0.948 -4.625 1.00 37.26 ? 41 SER B C 1 ATOM 3675 O O . SER B 1 41 ? 19.227 -0.649 -5.062 1.00 36.96 ? 41 SER B O 1 ATOM 3676 C CB . SER B 1 41 ? 16.619 1.049 -4.605 1.00 37.44 ? 41 SER B CB 1 ATOM 3677 O OG . SER B 1 41 ? 15.938 0.386 -5.660 1.00 39.59 ? 41 SER B OG 1 ATOM 3678 N N . PRO B 1 42 ? 17.525 -2.120 -4.872 1.00 38.68 ? 42 PRO B N 1 ATOM 3679 C CA . PRO B 1 42 ? 18.187 -3.141 -5.712 1.00 40.09 ? 42 PRO B CA 1 ATOM 3680 C C . PRO B 1 42 ? 18.000 -2.908 -7.192 1.00 41.04 ? 42 PRO B C 1 ATOM 3681 O O . PRO B 1 42 ? 18.650 -3.563 -8.004 1.00 41.88 ? 42 PRO B O 1 ATOM 3682 C CB . PRO B 1 42 ? 17.510 -4.467 -5.303 1.00 39.35 ? 42 PRO B CB 1 ATOM 3683 C CG . PRO B 1 42 ? 16.723 -4.146 -4.045 1.00 40.23 ? 42 PRO B CG 1 ATOM 3684 C CD . PRO B 1 42 ? 16.356 -2.668 -4.164 1.00 38.61 ? 42 PRO B CD 1 ATOM 3685 N N . GLU B 1 43 ? 17.092 -2.014 -7.544 1.00 41.99 ? 43 GLU B N 1 ATOM 3686 C CA . GLU B 1 43 ? 16.875 -1.673 -8.932 1.00 42.87 ? 43 GLU B CA 1 ATOM 3687 C C . GLU B 1 43 ? 18.149 -1.139 -9.564 1.00 42.70 ? 43 GLU B C 1 ATOM 3688 O O . GLU B 1 43 ? 18.984 -0.510 -8.893 1.00 42.86 ? 43 GLU B O 1 ATOM 3689 C CB . GLU B 1 43 ? 15.755 -0.646 -9.045 1.00 43.43 ? 43 GLU B CB 1 ATOM 3690 C CG . GLU B 1 43 ? 14.405 -1.267 -9.371 1.00 48.38 ? 43 GLU B CG 1 ATOM 3691 C CD . GLU B 1 43 ? 13.544 -1.520 -8.138 1.00 55.44 ? 43 GLU B CD 1 ATOM 3692 O OE1 . GLU B 1 43 ? 12.566 -0.745 -7.903 1.00 57.43 ? 43 GLU B OE1 1 ATOM 3693 O OE2 . GLU B 1 43 ? 13.829 -2.505 -7.413 1.00 58.10 ? 43 GLU B OE2 1 ATOM 3694 N N . VAL B 1 44 ? 18.314 -1.433 -10.847 1.00 42.44 ? 44 VAL B N 1 ATOM 3695 C CA . VAL B 1 44 ? 19.363 -0.835 -11.655 1.00 42.15 ? 44 VAL B CA 1 ATOM 3696 C C . VAL B 1 44 ? 19.049 0.657 -11.697 1.00 42.78 ? 44 VAL B C 1 ATOM 3697 O O . VAL B 1 44 ? 17.891 1.049 -11.919 1.00 43.40 ? 44 VAL B O 1 ATOM 3698 C CB . VAL B 1 44 ? 19.336 -1.383 -13.096 1.00 41.84 ? 44 VAL B CB 1 ATOM 3699 C CG1 . VAL B 1 44 ? 20.438 -0.787 -13.935 1.00 40.75 ? 44 VAL B CG1 1 ATOM 3700 C CG2 . VAL B 1 44 ? 19.411 -2.910 -13.091 1.00 41.61 ? 44 VAL B CG2 1 ATOM 3701 N N . PRO B 1 45 ? 20.054 1.498 -11.426 1.00 42.78 ? 45 PRO B N 1 ATOM 3702 C CA . PRO B 1 45 ? 19.789 2.932 -11.403 1.00 42.36 ? 45 PRO B CA 1 ATOM 3703 C C . PRO B 1 45 ? 19.617 3.510 -12.803 1.00 42.25 ? 45 PRO B C 1 ATOM 3704 O O . PRO B 1 45 ? 20.153 2.964 -13.791 1.00 41.97 ? 45 PRO B O 1 ATOM 3705 C CB . PRO B 1 45 ? 21.055 3.514 -10.748 1.00 42.25 ? 45 PRO B CB 1 ATOM 3706 C CG . PRO B 1 45 ? 21.668 2.397 -10.009 1.00 42.23 ? 45 PRO B CG 1 ATOM 3707 C CD . PRO B 1 45 ? 21.347 1.163 -10.800 1.00 42.80 ? 45 PRO B CD 1 ATOM 3708 N N . ALA B 1 46 ? 18.911 4.635 -12.873 1.00 41.10 ? 46 ALA B N 1 ATOM 3709 C CA . ALA B 1 46 ? 18.610 5.248 -14.144 1.00 40.31 ? 46 ALA B CA 1 ATOM 3710 C C . ALA B 1 46 ? 19.905 5.670 -14.830 1.00 39.16 ? 46 ALA B C 1 ATOM 3711 O O . ALA B 1 46 ? 20.810 6.192 -14.181 1.00 39.87 ? 46 ALA B O 1 ATOM 3712 C CB . ALA B 1 46 ? 17.657 6.428 -13.952 1.00 40.85 ? 46 ALA B CB 1 ATOM 3713 N N . GLY B 1 47 ? 20.017 5.408 -16.126 1.00 37.51 ? 47 GLY B N 1 ATOM 3714 C CA . GLY B 1 47 ? 21.249 5.737 -16.847 1.00 35.44 ? 47 GLY B CA 1 ATOM 3715 C C . GLY B 1 47 ? 22.263 4.613 -16.816 1.00 34.32 ? 47 GLY B C 1 ATOM 3716 O O . GLY B 1 47 ? 23.292 4.646 -17.513 1.00 34.23 ? 47 GLY B O 1 ATOM 3717 N N . CYS B 1 48 ? 21.971 3.599 -16.017 1.00 32.89 ? 48 CYS B N 1 ATOM 3718 C CA . CYS B 1 48 ? 22.889 2.464 -15.866 1.00 31.87 ? 48 CYS B CA 1 ATOM 3719 C C . CYS B 1 48 ? 22.438 1.197 -16.598 1.00 30.43 ? 48 CYS B C 1 ATOM 3720 O O . CYS B 1 48 ? 21.241 0.835 -16.624 1.00 29.18 ? 48 CYS B O 1 ATOM 3721 C CB . CYS B 1 48 ? 23.073 2.144 -14.369 1.00 31.92 ? 48 CYS B CB 1 ATOM 3722 S SG . CYS B 1 48 ? 23.797 3.550 -13.460 1.00 33.89 ? 48 CYS B SG 1 ATOM 3723 N N . ARG B 1 49 ? 23.411 0.495 -17.147 1.00 29.47 ? 49 ARG B N 1 ATOM 3724 C CA A ARG B 1 49 ? 23.165 -0.797 -17.779 0.50 29.13 ? 49 ARG B CA 1 ATOM 3725 C CA B ARG B 1 49 ? 23.096 -0.828 -17.663 0.50 28.79 ? 49 ARG B CA 1 ATOM 3726 C C . ARG B 1 49 ? 24.044 -1.920 -17.173 1.00 27.55 ? 49 ARG B C 1 ATOM 3727 O O . ARG B 1 49 ? 25.254 -1.785 -17.153 1.00 27.79 ? 49 ARG B O 1 ATOM 3728 C CB A ARG B 1 49 ? 23.447 -0.615 -19.275 0.50 29.38 ? 49 ARG B CB 1 ATOM 3729 C CB B ARG B 1 49 ? 22.935 -0.819 -19.190 0.50 28.96 ? 49 ARG B CB 1 ATOM 3730 C CG A ARG B 1 49 ? 23.018 -1.734 -20.182 0.50 32.44 ? 49 ARG B CG 1 ATOM 3731 C CG B ARG B 1 49 ? 21.701 -1.596 -19.646 0.50 30.15 ? 49 ARG B CG 1 ATOM 3732 C CD A ARG B 1 49 ? 23.393 -1.383 -21.603 0.50 35.98 ? 49 ARG B CD 1 ATOM 3733 C CD B ARG B 1 49 ? 21.490 -1.544 -21.155 0.50 32.87 ? 49 ARG B CD 1 ATOM 3734 N NE A ARG B 1 49 ? 24.545 -0.485 -21.658 0.50 38.38 ? 49 ARG B NE 1 ATOM 3735 N NE B ARG B 1 49 ? 20.090 -1.796 -21.463 0.50 34.10 ? 49 ARG B NE 1 ATOM 3736 C CZ A ARG B 1 49 ? 25.759 -0.848 -22.060 0.50 39.73 ? 49 ARG B CZ 1 ATOM 3737 C CZ B ARG B 1 49 ? 19.230 -0.837 -21.787 0.50 35.13 ? 49 ARG B CZ 1 ATOM 3738 N NH1 A ARG B 1 49 ? 25.991 -2.105 -22.428 0.50 37.60 ? 49 ARG B NH1 1 ATOM 3739 N NH1 B ARG B 1 49 ? 19.640 0.421 -21.868 0.50 34.67 ? 49 ARG B NH1 1 ATOM 3740 N NH2 A ARG B 1 49 ? 26.746 0.051 -22.091 0.50 40.80 ? 49 ARG B NH2 1 ATOM 3741 N NH2 B ARG B 1 49 ? 17.963 -1.138 -22.031 0.50 35.04 ? 49 ARG B NH2 1 ATOM 3742 N N . VAL B 1 50 ? 23.458 -3.014 -16.713 1.00 26.55 ? 50 VAL B N 1 ATOM 3743 C CA . VAL B 1 50 ? 24.231 -4.201 -16.287 1.00 23.77 ? 50 VAL B CA 1 ATOM 3744 C C . VAL B 1 50 ? 24.916 -4.900 -17.478 1.00 23.94 ? 50 VAL B C 1 ATOM 3745 O O . VAL B 1 50 ? 24.265 -5.270 -18.456 1.00 24.28 ? 50 VAL B O 1 ATOM 3746 C CB . VAL B 1 50 ? 23.325 -5.249 -15.601 1.00 23.67 ? 50 VAL B CB 1 ATOM 3747 C CG1 . VAL B 1 50 ? 24.163 -6.428 -15.021 1.00 21.80 ? 50 VAL B CG1 1 ATOM 3748 C CG2 . VAL B 1 50 ? 22.460 -4.619 -14.519 1.00 23.68 ? 50 VAL B CG2 1 ATOM 3749 N N . THR B 1 51 ? 26.217 -5.133 -17.347 1.00 23.18 ? 51 THR B N 1 ATOM 3750 C CA . THR B 1 51 ? 27.038 -5.748 -18.352 1.00 23.42 ? 51 THR B CA 1 ATOM 3751 C C . THR B 1 51 ? 27.773 -7.026 -17.858 1.00 23.23 ? 51 THR B C 1 ATOM 3752 O O . THR B 1 51 ? 28.582 -7.616 -18.597 1.00 22.88 ? 51 THR B O 1 ATOM 3753 C CB . THR B 1 51 ? 28.060 -4.751 -18.815 1.00 24.30 ? 51 THR B CB 1 ATOM 3754 O OG1 . THR B 1 51 ? 28.907 -4.421 -17.716 1.00 24.90 ? 51 THR B OG1 1 ATOM 3755 C CG2 . THR B 1 51 ? 27.389 -3.428 -19.306 1.00 24.63 ? 51 THR B CG2 1 ATOM 3756 N N . PHE B 1 52 ? 27.491 -7.438 -16.614 1.00 22.69 ? 52 PHE B N 1 ATOM 3757 C CA . PHE B 1 52 ? 28.081 -8.640 -15.990 1.00 20.57 ? 52 PHE B CA 1 ATOM 3758 C C . PHE B 1 52 ? 27.177 -9.139 -14.854 1.00 19.61 ? 52 PHE B C 1 ATOM 3759 O O . PHE B 1 52 ? 26.660 -8.358 -14.049 1.00 19.48 ? 52 PHE B O 1 ATOM 3760 C CB . PHE B 1 52 ? 29.464 -8.285 -15.442 1.00 20.51 ? 52 PHE B CB 1 ATOM 3761 C CG . PHE B 1 52 ? 30.156 -9.400 -14.663 1.00 19.71 ? 52 PHE B CG 1 ATOM 3762 C CD1 . PHE B 1 52 ? 29.893 -9.597 -13.311 1.00 18.69 ? 52 PHE B CD1 1 ATOM 3763 C CD2 . PHE B 1 52 ? 31.127 -10.198 -15.267 1.00 18.81 ? 52 PHE B CD2 1 ATOM 3764 C CE1 . PHE B 1 52 ? 30.555 -10.619 -12.583 1.00 18.20 ? 52 PHE B CE1 1 ATOM 3765 C CE2 . PHE B 1 52 ? 31.806 -11.196 -14.560 1.00 19.59 ? 52 PHE B CE2 1 ATOM 3766 C CZ . PHE B 1 52 ? 31.515 -11.426 -13.221 1.00 19.62 ? 52 PHE B CZ 1 ATOM 3767 N N . ALA B 1 53 ? 26.972 -10.434 -14.753 1.00 19.31 ? 53 ALA B N 1 ATOM 3768 C CA . ALA B 1 53 ? 26.260 -10.929 -13.574 1.00 18.17 ? 53 ALA B CA 1 ATOM 3769 C C . ALA B 1 53 ? 26.770 -12.300 -13.235 1.00 17.90 ? 53 ALA B C 1 ATOM 3770 O O . ALA B 1 53 ? 26.752 -13.174 -14.077 1.00 18.10 ? 53 ALA B O 1 ATOM 3771 C CB . ALA B 1 53 ? 24.768 -10.908 -13.776 1.00 17.96 ? 53 ALA B CB 1 ATOM 3772 N N . GLN B 1 54 ? 27.298 -12.455 -12.020 1.00 17.46 ? 54 GLN B N 1 ATOM 3773 C CA . GLN B 1 54 ? 27.740 -13.768 -11.465 1.00 16.80 ? 54 GLN B CA 1 ATOM 3774 C C . GLN B 1 54 ? 26.824 -14.104 -10.287 1.00 15.94 ? 54 GLN B C 1 ATOM 3775 O O . GLN B 1 54 ? 26.531 -13.240 -9.439 1.00 16.27 ? 54 GLN B O 1 ATOM 3776 C CB . GLN B 1 54 ? 29.186 -13.701 -10.941 1.00 17.19 ? 54 GLN B CB 1 ATOM 3777 C CG . GLN B 1 54 ? 29.705 -15.014 -10.305 1.00 18.23 ? 54 GLN B CG 1 ATOM 3778 C CD . GLN B 1 54 ? 31.221 -15.109 -10.444 1.00 22.70 ? 54 GLN B CD 1 ATOM 3779 O OE1 . GLN B 1 54 ? 31.767 -14.891 -11.514 1.00 23.65 ? 54 GLN B OE1 1 ATOM 3780 N NE2 . GLN B 1 54 ? 31.911 -15.412 -9.352 1.00 24.95 ? 54 GLN B NE2 1 ATOM 3781 N N . VAL B 1 55 ? 26.331 -15.327 -10.239 1.00 15.21 ? 55 VAL B N 1 ATOM 3782 C CA . VAL B 1 55 ? 25.570 -15.776 -9.063 1.00 15.52 ? 55 VAL B CA 1 ATOM 3783 C C . VAL B 1 55 ? 26.383 -16.913 -8.404 1.00 15.61 ? 55 VAL B C 1 ATOM 3784 O O . VAL B 1 55 ? 26.919 -17.791 -9.082 1.00 16.98 ? 55 VAL B O 1 ATOM 3785 C CB . VAL B 1 55 ? 24.107 -16.163 -9.401 1.00 16.23 ? 55 VAL B CB 1 ATOM 3786 C CG1 . VAL B 1 55 ? 24.071 -17.233 -10.481 1.00 17.03 ? 55 VAL B CG1 1 ATOM 3787 C CG2 . VAL B 1 55 ? 23.299 -16.640 -8.151 1.00 15.92 ? 55 VAL B CG2 1 ATOM 3788 N N . LEU B 1 56 ? 26.551 -16.843 -7.086 1.00 15.07 ? 56 LEU B N 1 ATOM 3789 C CA . LEU B 1 56 ? 27.121 -17.944 -6.303 1.00 13.63 ? 56 LEU B CA 1 ATOM 3790 C C . LEU B 1 56 ? 25.936 -18.422 -5.472 1.00 13.74 ? 56 LEU B C 1 ATOM 3791 O O . LEU B 1 56 ? 25.344 -17.607 -4.771 1.00 14.76 ? 56 LEU B O 1 ATOM 3792 C CB . LEU B 1 56 ? 28.213 -17.397 -5.389 1.00 12.36 ? 56 LEU B CB 1 ATOM 3793 C CG . LEU B 1 56 ? 28.816 -18.376 -4.348 1.00 14.30 ? 56 LEU B CG 1 ATOM 3794 C CD1 . LEU B 1 56 ? 29.337 -19.676 -4.947 1.00 8.88 ? 56 LEU B CD1 1 ATOM 3795 C CD2 . LEU B 1 56 ? 29.955 -17.683 -3.626 1.00 11.51 ? 56 LEU B CD2 1 ATOM 3796 N N . SER B 1 57 ? 25.542 -19.691 -5.580 1.00 14.25 ? 57 SER B N 1 ATOM 3797 C CA . SER B 1 57 ? 24.293 -20.116 -4.961 1.00 14.79 ? 57 SER B CA 1 ATOM 3798 C C . SER B 1 57 ? 24.633 -21.308 -4.078 1.00 14.95 ? 57 SER B C 1 ATOM 3799 O O . SER B 1 57 ? 25.515 -22.070 -4.418 1.00 14.81 ? 57 SER B O 1 ATOM 3800 C CB . SER B 1 57 ? 23.303 -20.575 -6.047 1.00 15.75 ? 57 SER B CB 1 ATOM 3801 O OG . SER B 1 57 ? 22.130 -21.166 -5.484 1.00 14.84 ? 57 SER B OG 1 ATOM 3802 N N . ARG B 1 58 ? 23.942 -21.441 -2.953 1.00 15.32 ? 58 ARG B N 1 ATOM 3803 C CA . ARG B 1 58 ? 23.979 -22.652 -2.128 1.00 15.75 ? 58 ARG B CA 1 ATOM 3804 C C . ARG B 1 58 ? 22.977 -23.680 -2.675 1.00 16.04 ? 58 ARG B C 1 ATOM 3805 O O . ARG B 1 58 ? 22.091 -23.295 -3.437 1.00 16.09 ? 58 ARG B O 1 ATOM 3806 C CB . ARG B 1 58 ? 23.605 -22.344 -0.700 1.00 15.31 ? 58 ARG B CB 1 ATOM 3807 C CG . ARG B 1 58 ? 23.915 -23.563 0.282 1.00 14.74 ? 58 ARG B CG 1 ATOM 3808 C CD . ARG B 1 58 ? 23.640 -23.168 1.749 1.00 11.34 ? 58 ARG B CD 1 ATOM 3809 N NE . ARG B 1 58 ? 23.552 -24.353 2.607 1.00 15.70 ? 58 ARG B NE 1 ATOM 3810 C CZ . ARG B 1 58 ? 22.878 -24.427 3.761 1.00 13.16 ? 58 ARG B CZ 1 ATOM 3811 N NH1 . ARG B 1 58 ? 22.262 -23.374 4.289 1.00 10.10 ? 58 ARG B NH1 1 ATOM 3812 N NH2 . ARG B 1 58 ? 22.849 -25.583 4.406 1.00 16.21 ? 58 ARG B NH2 1 ATOM 3813 N N . HIS B 1 59 ? 23.111 -24.969 -2.290 1.00 14.97 ? 59 HIS B N 1 ATOM 3814 C CA . HIS B 1 59 ? 22.185 -25.974 -2.739 1.00 14.69 ? 59 HIS B CA 1 ATOM 3815 C C . HIS B 1 59 ? 20.917 -25.708 -1.996 1.00 15.03 ? 59 HIS B C 1 ATOM 3816 O O . HIS B 1 59 ? 20.880 -24.837 -1.100 1.00 14.82 ? 59 HIS B O 1 ATOM 3817 C CB . HIS B 1 59 ? 22.689 -27.349 -2.388 1.00 15.43 ? 59 HIS B CB 1 ATOM 3818 C CG . HIS B 1 59 ? 22.920 -27.515 -0.927 1.00 15.97 ? 59 HIS B CG 1 ATOM 3819 N ND1 . HIS B 1 59 ? 21.877 -27.541 -0.013 1.00 15.55 ? 59 HIS B ND1 1 ATOM 3820 C CD2 . HIS B 1 59 ? 24.071 -27.584 -0.215 1.00 11.88 ? 59 HIS B CD2 1 ATOM 3821 C CE1 . HIS B 1 59 ? 22.390 -27.643 1.205 1.00 15.84 ? 59 HIS B CE1 1 ATOM 3822 N NE2 . HIS B 1 59 ? 23.714 -27.665 1.106 1.00 14.27 ? 59 HIS B NE2 1 ATOM 3823 N N . GLY B 1 60 ? 19.840 -26.407 -2.345 1.00 14.70 ? 60 GLY B N 1 ATOM 3824 C CA . GLY B 1 60 ? 18.565 -26.080 -1.716 1.00 14.01 ? 60 GLY B CA 1 ATOM 3825 C C . GLY B 1 60 ? 18.335 -26.820 -0.420 1.00 15.33 ? 60 GLY B C 1 ATOM 3826 O O . GLY B 1 60 ? 19.189 -27.553 0.026 1.00 15.32 ? 60 GLY B O 1 ATOM 3827 N N . ALA B 1 61 ? 17.171 -26.606 0.199 1.00 17.25 ? 61 ALA B N 1 ATOM 3828 C CA . ALA B 1 61 ? 16.784 -27.299 1.417 1.00 18.09 ? 61 ALA B CA 1 ATOM 3829 C C . ALA B 1 61 ? 17.032 -28.793 1.259 1.00 19.97 ? 61 ALA B C 1 ATOM 3830 O O . ALA B 1 61 ? 16.737 -29.379 0.240 1.00 21.60 ? 61 ALA B O 1 ATOM 3831 C CB . ALA B 1 61 ? 15.362 -26.991 1.775 1.00 16.29 ? 61 ALA B CB 1 ATOM 3832 N N . ARG B 1 62 ? 17.643 -29.410 2.262 1.00 21.11 ? 62 ARG B N 1 ATOM 3833 C CA . ARG B 1 62 ? 17.936 -30.825 2.204 1.00 20.89 ? 62 ARG B CA 1 ATOM 3834 C C . ARG B 1 62 ? 17.384 -31.575 3.425 1.00 20.97 ? 62 ARG B C 1 ATOM 3835 O O . ARG B 1 62 ? 16.813 -30.983 4.363 1.00 21.23 ? 62 ARG B O 1 ATOM 3836 C CB . ARG B 1 62 ? 19.431 -31.033 2.076 1.00 21.37 ? 62 ARG B CB 1 ATOM 3837 C CG . ARG B 1 62 ? 20.242 -30.420 3.233 1.00 22.31 ? 62 ARG B CG 1 ATOM 3838 C CD . ARG B 1 62 ? 21.705 -30.972 3.269 1.00 21.78 ? 62 ARG B CD 1 ATOM 3839 N NE . ARG B 1 62 ? 22.526 -30.290 4.305 1.00 25.53 ? 62 ARG B NE 1 ATOM 3840 C CZ . ARG B 1 62 ? 22.544 -30.588 5.628 1.00 24.40 ? 62 ARG B CZ 1 ATOM 3841 N NH1 . ARG B 1 62 ? 21.764 -31.528 6.130 1.00 21.70 ? 62 ARG B NH1 1 ATOM 3842 N NH2 . ARG B 1 62 ? 23.311 -29.883 6.465 1.00 23.14 ? 62 ARG B NH2 1 ATOM 3843 N N . TYR B 1 63 ? 17.456 -32.887 3.343 1.00 20.79 ? 63 TYR B N 1 ATOM 3844 C CA . TYR B 1 63 ? 17.350 -33.751 4.494 1.00 21.97 ? 63 TYR B CA 1 ATOM 3845 C C . TYR B 1 63 ? 18.621 -33.650 5.353 1.00 22.91 ? 63 TYR B C 1 ATOM 3846 O O . TYR B 1 63 ? 19.724 -33.229 4.859 1.00 21.27 ? 63 TYR B O 1 ATOM 3847 C CB . TYR B 1 63 ? 17.187 -35.192 4.042 1.00 21.95 ? 63 TYR B CB 1 ATOM 3848 C CG . TYR B 1 63 ? 15.882 -35.475 3.330 1.00 24.85 ? 63 TYR B CG 1 ATOM 3849 C CD1 . TYR B 1 63 ? 14.626 -35.203 3.938 1.00 25.65 ? 63 TYR B CD1 1 ATOM 3850 C CD2 . TYR B 1 63 ? 15.892 -36.018 2.037 1.00 27.28 ? 63 TYR B CD2 1 ATOM 3851 C CE1 . TYR B 1 63 ? 13.427 -35.472 3.253 1.00 27.77 ? 63 TYR B CE1 1 ATOM 3852 C CE2 . TYR B 1 63 ? 14.696 -36.284 1.336 1.00 29.05 ? 63 TYR B CE2 1 ATOM 3853 C CZ . TYR B 1 63 ? 13.483 -36.009 1.940 1.00 30.20 ? 63 TYR B CZ 1 ATOM 3854 O OH . TYR B 1 63 ? 12.354 -36.280 1.212 1.00 33.60 ? 63 TYR B OH 1 ATOM 3855 N N . PRO B 1 64 ? 18.512 -34.084 6.635 1.00 24.13 ? 64 PRO B N 1 ATOM 3856 C CA . PRO B 1 64 ? 19.706 -34.076 7.529 1.00 23.58 ? 64 PRO B CA 1 ATOM 3857 C C . PRO B 1 64 ? 20.782 -34.983 6.994 1.00 23.76 ? 64 PRO B C 1 ATOM 3858 O O . PRO B 1 64 ? 20.469 -35.983 6.385 1.00 23.27 ? 64 PRO B O 1 ATOM 3859 C CB . PRO B 1 64 ? 19.150 -34.686 8.821 1.00 23.54 ? 64 PRO B CB 1 ATOM 3860 C CG . PRO B 1 64 ? 17.638 -34.345 8.791 1.00 24.10 ? 64 PRO B CG 1 ATOM 3861 C CD . PRO B 1 64 ? 17.300 -34.563 7.336 1.00 23.94 ? 64 PRO B CD 1 ATOM 3862 N N . THR B 1 65 ? 22.038 -34.697 7.245 1.00 24.97 ? 65 THR B N 1 ATOM 3863 C CA . THR B 1 65 ? 23.061 -35.646 6.874 1.00 27.38 ? 65 THR B CA 1 ATOM 3864 C C . THR B 1 65 ? 22.775 -37.007 7.529 1.00 29.07 ? 65 THR B C 1 ATOM 3865 O O . THR B 1 65 ? 21.938 -37.093 8.432 1.00 28.77 ? 65 THR B O 1 ATOM 3866 C CB . THR B 1 65 ? 24.479 -35.148 7.217 1.00 27.87 ? 65 THR B CB 1 ATOM 3867 O OG1 . THR B 1 65 ? 24.611 -35.041 8.631 1.00 30.99 ? 65 THR B OG1 1 ATOM 3868 C CG2 . THR B 1 65 ? 24.794 -33.754 6.558 1.00 25.81 ? 65 THR B CG2 1 ATOM 3869 N N . ASP B 1 66 ? 23.414 -38.080 7.051 1.00 30.69 ? 66 ASP B N 1 ATOM 3870 C CA . ASP B 1 66 ? 23.097 -39.421 7.550 1.00 33.64 ? 66 ASP B CA 1 ATOM 3871 C C . ASP B 1 66 ? 23.443 -39.544 9.043 1.00 34.02 ? 66 ASP B C 1 ATOM 3872 O O . ASP B 1 66 ? 22.610 -39.962 9.845 1.00 34.57 ? 66 ASP B O 1 ATOM 3873 C CB . ASP B 1 66 ? 23.757 -40.544 6.730 1.00 34.51 ? 66 ASP B CB 1 ATOM 3874 C CG . ASP B 1 66 ? 23.229 -41.959 7.126 1.00 39.29 ? 66 ASP B CG 1 ATOM 3875 O OD1 . ASP B 1 66 ? 21.975 -42.126 7.251 1.00 40.53 ? 66 ASP B OD1 1 ATOM 3876 O OD2 . ASP B 1 66 ? 24.075 -42.886 7.333 1.00 42.57 ? 66 ASP B OD2 1 ATOM 3877 N N . SER B 1 67 ? 24.648 -39.104 9.399 1.00 35.05 ? 67 SER B N 1 ATOM 3878 C CA . SER B 1 67 ? 25.092 -38.894 10.774 1.00 35.20 ? 67 SER B CA 1 ATOM 3879 C C . SER B 1 67 ? 24.030 -38.225 11.664 1.00 35.18 ? 67 SER B C 1 ATOM 3880 O O . SER B 1 67 ? 23.564 -38.812 12.636 1.00 35.06 ? 67 SER B O 1 ATOM 3881 C CB . SER B 1 67 ? 26.331 -38.016 10.743 1.00 36.48 ? 67 SER B CB 1 ATOM 3882 O OG . SER B 1 67 ? 27.362 -38.622 11.478 1.00 39.38 ? 67 SER B OG 1 ATOM 3883 N N . LYS B 1 68 ? 23.643 -36.995 11.324 1.00 34.57 ? 68 LYS B N 1 ATOM 3884 C CA . LYS B 1 68 ? 22.736 -36.228 12.161 1.00 33.46 ? 68 LYS B CA 1 ATOM 3885 C C . LYS B 1 68 ? 21.384 -36.875 12.204 1.00 32.89 ? 68 LYS B C 1 ATOM 3886 O O . LYS B 1 68 ? 20.705 -36.856 13.238 1.00 32.26 ? 68 LYS B O 1 ATOM 3887 C CB . LYS B 1 68 ? 22.609 -34.791 11.648 1.00 33.63 ? 68 LYS B CB 1 ATOM 3888 C CG . LYS B 1 68 ? 23.798 -33.902 11.969 1.00 34.37 ? 68 LYS B CG 1 ATOM 3889 C CD . LYS B 1 68 ? 23.740 -33.308 13.393 1.00 35.65 ? 68 LYS B CD 1 ATOM 3890 C CE . LYS B 1 68 ? 24.945 -32.431 13.645 1.00 36.47 ? 68 LYS B CE 1 ATOM 3891 N NZ . LYS B 1 68 ? 24.399 -31.236 14.321 1.00 40.86 ? 68 LYS B NZ 1 ATOM 3892 N N . GLY B 1 69 ? 20.994 -37.441 11.069 1.00 33.09 ? 69 GLY B N 1 ATOM 3893 C CA . GLY B 1 69 ? 19.718 -38.109 10.936 1.00 33.70 ? 69 GLY B CA 1 ATOM 3894 C C . GLY B 1 69 ? 19.601 -39.330 11.849 1.00 34.39 ? 69 GLY B C 1 ATOM 3895 O O . GLY B 1 69 ? 18.537 -39.548 12.440 1.00 33.41 ? 69 GLY B O 1 ATOM 3896 N N . LYS B 1 70 ? 20.693 -40.097 11.983 1.00 35.34 ? 70 LYS B N 1 ATOM 3897 C CA . LYS B 1 70 ? 20.753 -41.240 12.924 1.00 37.16 ? 70 LYS B CA 1 ATOM 3898 C C . LYS B 1 70 ? 20.594 -40.778 14.391 1.00 36.36 ? 70 LYS B C 1 ATOM 3899 O O . LYS B 1 70 ? 19.853 -41.377 15.179 1.00 37.24 ? 70 LYS B O 1 ATOM 3900 C CB . LYS B 1 70 ? 22.060 -42.023 12.791 1.00 37.69 ? 70 LYS B CB 1 ATOM 3901 C CG . LYS B 1 70 ? 22.399 -42.542 11.419 1.00 43.22 ? 70 LYS B CG 1 ATOM 3902 C CD . LYS B 1 70 ? 21.909 -43.968 11.124 1.00 49.33 ? 70 LYS B CD 1 ATOM 3903 C CE . LYS B 1 70 ? 22.823 -44.574 10.038 1.00 51.05 ? 70 LYS B CE 1 ATOM 3904 N NZ . LYS B 1 70 ? 23.012 -46.066 10.146 1.00 54.50 ? 70 LYS B NZ 1 ATOM 3905 N N . LYS B 1 71 ? 21.283 -39.702 14.738 1.00 35.41 ? 71 LYS B N 1 ATOM 3906 C CA . LYS B 1 71 ? 21.190 -39.131 16.076 1.00 34.37 ? 71 LYS B CA 1 ATOM 3907 C C . LYS B 1 71 ? 19.801 -38.536 16.351 1.00 34.19 ? 71 LYS B C 1 ATOM 3908 O O . LYS B 1 71 ? 19.272 -38.699 17.438 1.00 34.39 ? 71 LYS B O 1 ATOM 3909 C CB . LYS B 1 71 ? 22.320 -38.122 16.298 1.00 33.99 ? 71 LYS B CB 1 ATOM 3910 C CG . LYS B 1 71 ? 23.711 -38.769 16.146 1.00 35.24 ? 71 LYS B CG 1 ATOM 3911 C CD . LYS B 1 71 ? 24.841 -37.762 16.363 1.00 40.42 ? 71 LYS B CD 1 ATOM 3912 C CE . LYS B 1 71 ? 26.194 -38.370 15.981 1.00 44.62 ? 71 LYS B CE 1 ATOM 3913 N NZ . LYS B 1 71 ? 27.265 -37.360 16.046 1.00 45.41 ? 71 LYS B NZ 1 ATOM 3914 N N . TYR B 1 72 ? 19.198 -37.852 15.380 1.00 33.54 ? 72 TYR B N 1 ATOM 3915 C CA . TYR B 1 72 ? 17.838 -37.329 15.590 1.00 32.99 ? 72 TYR B CA 1 ATOM 3916 C C . TYR B 1 72 ? 16.864 -38.491 15.870 1.00 32.26 ? 72 TYR B C 1 ATOM 3917 O O . TYR B 1 72 ? 16.042 -38.457 16.778 1.00 30.72 ? 72 TYR B O 1 ATOM 3918 C CB . TYR B 1 72 ? 17.337 -36.534 14.370 1.00 32.09 ? 72 TYR B CB 1 ATOM 3919 C CG . TYR B 1 72 ? 18.092 -35.267 14.054 1.00 32.90 ? 72 TYR B CG 1 ATOM 3920 C CD1 . TYR B 1 72 ? 18.942 -34.678 14.984 1.00 32.00 ? 72 TYR B CD1 1 ATOM 3921 C CD2 . TYR B 1 72 ? 17.912 -34.606 12.837 1.00 31.36 ? 72 TYR B CD2 1 ATOM 3922 C CE1 . TYR B 1 72 ? 19.602 -33.497 14.689 1.00 31.40 ? 72 TYR B CE1 1 ATOM 3923 C CE2 . TYR B 1 72 ? 18.568 -33.420 12.561 1.00 28.06 ? 72 TYR B CE2 1 ATOM 3924 C CZ . TYR B 1 72 ? 19.392 -32.873 13.476 1.00 29.48 ? 72 TYR B CZ 1 ATOM 3925 O OH . TYR B 1 72 ? 20.043 -31.695 13.212 1.00 24.91 ? 72 TYR B OH 1 ATOM 3926 N N . SER B 1 73 ? 17.006 -39.516 15.052 1.00 32.88 ? 73 SER B N 1 ATOM 3927 C CA . SER B 1 73 ? 16.130 -40.664 15.020 1.00 33.56 ? 73 SER B CA 1 ATOM 3928 C C . SER B 1 73 ? 16.284 -41.445 16.351 1.00 33.37 ? 73 SER B C 1 ATOM 3929 O O . SER B 1 73 ? 15.268 -41.746 17.011 1.00 33.56 ? 73 SER B O 1 ATOM 3930 C CB . SER B 1 73 ? 16.521 -41.511 13.800 1.00 33.40 ? 73 SER B CB 1 ATOM 3931 O OG . SER B 1 73 ? 15.648 -42.576 13.575 1.00 35.08 ? 73 SER B OG 1 ATOM 3932 N N . ALA B 1 74 ? 17.537 -41.705 16.756 1.00 33.09 ? 74 ALA B N 1 ATOM 3933 C CA . ALA B 1 74 ? 17.817 -42.369 18.053 1.00 32.81 ? 74 ALA B CA 1 ATOM 3934 C C . ALA B 1 74 ? 17.295 -41.576 19.230 1.00 33.03 ? 74 ALA B C 1 ATOM 3935 O O . ALA B 1 74 ? 16.716 -42.168 20.154 1.00 32.99 ? 74 ALA B O 1 ATOM 3936 C CB . ALA B 1 74 ? 19.289 -42.653 18.245 1.00 32.76 ? 74 ALA B CB 1 ATOM 3937 N N . LEU B 1 75 ? 17.472 -40.248 19.207 1.00 32.53 ? 75 LEU B N 1 ATOM 3938 C CA . LEU B 1 75 ? 17.022 -39.418 20.319 1.00 32.92 ? 75 LEU B CA 1 ATOM 3939 C C . LEU B 1 75 ? 15.509 -39.512 20.481 1.00 33.85 ? 75 LEU B C 1 ATOM 3940 O O . LEU B 1 75 ? 14.995 -39.582 21.600 1.00 34.36 ? 75 LEU B O 1 ATOM 3941 C CB . LEU B 1 75 ? 17.452 -37.966 20.167 1.00 32.04 ? 75 LEU B CB 1 ATOM 3942 C CG . LEU B 1 75 ? 16.859 -36.873 21.087 1.00 34.04 ? 75 LEU B CG 1 ATOM 3943 C CD1 . LEU B 1 75 ? 16.997 -37.234 22.566 1.00 33.34 ? 75 LEU B CD1 1 ATOM 3944 C CD2 . LEU B 1 75 ? 17.479 -35.511 20.839 1.00 30.01 ? 75 LEU B CD2 1 ATOM 3945 N N . ILE B 1 76 ? 14.793 -39.529 19.374 1.00 34.79 ? 76 ILE B N 1 ATOM 3946 C CA . ILE B 1 76 ? 13.343 -39.543 19.448 1.00 35.75 ? 76 ILE B CA 1 ATOM 3947 C C . ILE B 1 76 ? 12.813 -40.882 19.957 1.00 37.16 ? 76 ILE B C 1 ATOM 3948 O O . ILE B 1 76 ? 11.878 -40.891 20.759 1.00 37.33 ? 76 ILE B O 1 ATOM 3949 C CB . ILE B 1 76 ? 12.665 -39.063 18.128 1.00 35.60 ? 76 ILE B CB 1 ATOM 3950 C CG1 . ILE B 1 76 ? 12.965 -37.579 17.909 1.00 34.08 ? 76 ILE B CG1 1 ATOM 3951 C CG2 . ILE B 1 76 ? 11.192 -39.272 18.183 1.00 32.54 ? 76 ILE B CG2 1 ATOM 3952 C CD1 . ILE B 1 76 ? 13.062 -37.189 16.437 1.00 35.41 ? 76 ILE B CD1 1 ATOM 3953 N N . GLU B 1 77 ? 13.411 -41.991 19.526 1.00 38.34 ? 77 GLU B N 1 ATOM 3954 C CA . GLU B 1 77 ? 13.090 -43.284 20.115 1.00 40.61 ? 77 GLU B CA 1 ATOM 3955 C C . GLU B 1 77 ? 13.252 -43.244 21.637 1.00 40.41 ? 77 GLU B C 1 ATOM 3956 O O . GLU B 1 77 ? 12.320 -43.564 22.377 1.00 40.57 ? 77 GLU B O 1 ATOM 3957 C CB . GLU B 1 77 ? 14.011 -44.377 19.598 1.00 41.68 ? 77 GLU B CB 1 ATOM 3958 C CG . GLU B 1 77 ? 14.031 -44.552 18.131 1.00 47.25 ? 77 GLU B CG 1 ATOM 3959 C CD . GLU B 1 77 ? 13.856 -46.000 17.745 1.00 53.98 ? 77 GLU B CD 1 ATOM 3960 O OE1 . GLU B 1 77 ? 14.306 -46.909 18.496 1.00 56.50 ? 77 GLU B OE1 1 ATOM 3961 O OE2 . GLU B 1 77 ? 13.229 -46.223 16.692 1.00 57.44 ? 77 GLU B OE2 1 ATOM 3962 N N . GLU B 1 78 ? 14.451 -42.873 22.088 1.00 40.28 ? 78 GLU B N 1 ATOM 3963 C CA . GLU B 1 78 ? 14.746 -42.763 23.530 1.00 40.05 ? 78 GLU B CA 1 ATOM 3964 C C . GLU B 1 78 ? 13.711 -41.928 24.270 1.00 39.34 ? 78 GLU B C 1 ATOM 3965 O O . GLU B 1 78 ? 13.230 -42.334 25.323 1.00 38.94 ? 78 GLU B O 1 ATOM 3966 C CB . GLU B 1 78 ? 16.148 -42.208 23.775 1.00 40.18 ? 78 GLU B CB 1 ATOM 3967 C CG . GLU B 1 78 ? 17.253 -43.243 23.644 1.00 41.96 ? 78 GLU B CG 1 ATOM 3968 C CD . GLU B 1 78 ? 18.650 -42.708 23.992 1.00 46.56 ? 78 GLU B CD 1 ATOM 3969 O OE1 . GLU B 1 78 ? 19.613 -43.328 23.497 1.00 48.73 ? 78 GLU B OE1 1 ATOM 3970 O OE2 . GLU B 1 78 ? 18.803 -41.691 24.741 1.00 47.79 ? 78 GLU B OE2 1 ATOM 3971 N N . ILE B 1 79 ? 13.345 -40.783 23.711 1.00 38.54 ? 79 ILE B N 1 ATOM 3972 C CA . ILE B 1 79 ? 12.262 -40.019 24.287 1.00 38.40 ? 79 ILE B CA 1 ATOM 3973 C C . ILE B 1 79 ? 10.977 -40.847 24.382 1.00 39.53 ? 79 ILE B C 1 ATOM 3974 O O . ILE B 1 79 ? 10.262 -40.765 25.372 1.00 38.95 ? 79 ILE B O 1 ATOM 3975 C CB . ILE B 1 79 ? 12.051 -38.681 23.581 1.00 38.19 ? 79 ILE B CB 1 ATOM 3976 C CG1 . ILE B 1 79 ? 13.247 -37.784 23.871 1.00 36.49 ? 79 ILE B CG1 1 ATOM 3977 C CG2 . ILE B 1 79 ? 10.737 -38.005 24.029 1.00 36.99 ? 79 ILE B CG2 1 ATOM 3978 C CD1 . ILE B 1 79 ? 13.348 -36.554 22.975 1.00 36.76 ? 79 ILE B CD1 1 ATOM 3979 N N . GLN B 1 80 ? 10.727 -41.682 23.379 1.00 40.99 ? 80 GLN B N 1 ATOM 3980 C CA . GLN B 1 80 ? 9.511 -42.498 23.330 1.00 42.72 ? 80 GLN B CA 1 ATOM 3981 C C . GLN B 1 80 ? 9.548 -43.675 24.299 1.00 43.03 ? 80 GLN B C 1 ATOM 3982 O O . GLN B 1 80 ? 8.523 -44.048 24.852 1.00 42.90 ? 80 GLN B O 1 ATOM 3983 C CB . GLN B 1 80 ? 9.240 -42.990 21.900 1.00 42.85 ? 80 GLN B CB 1 ATOM 3984 C CG . GLN B 1 80 ? 8.639 -41.920 21.006 1.00 44.20 ? 80 GLN B CG 1 ATOM 3985 C CD . GLN B 1 80 ? 8.662 -42.246 19.508 1.00 44.94 ? 80 GLN B CD 1 ATOM 3986 O OE1 . GLN B 1 80 ? 9.120 -43.323 19.058 1.00 43.89 ? 80 GLN B OE1 1 ATOM 3987 N NE2 . GLN B 1 80 ? 8.155 -41.300 18.732 1.00 42.27 ? 80 GLN B NE2 1 ATOM 3988 N N . GLN B 1 81 ? 10.723 -44.265 24.483 1.00 44.20 ? 81 GLN B N 1 ATOM 3989 C CA . GLN B 1 81 ? 10.874 -45.370 25.416 1.00 45.93 ? 81 GLN B CA 1 ATOM 3990 C C . GLN B 1 81 ? 10.755 -44.941 26.890 1.00 46.17 ? 81 GLN B C 1 ATOM 3991 O O . GLN B 1 81 ? 10.290 -45.730 27.734 1.00 46.56 ? 81 GLN B O 1 ATOM 3992 C CB . GLN B 1 81 ? 12.199 -46.061 25.190 1.00 46.67 ? 81 GLN B CB 1 ATOM 3993 C CG . GLN B 1 81 ? 12.169 -46.995 24.011 1.00 51.24 ? 81 GLN B CG 1 ATOM 3994 C CD . GLN B 1 81 ? 13.522 -47.059 23.310 1.00 58.99 ? 81 GLN B CD 1 ATOM 3995 O OE1 . GLN B 1 81 ? 14.566 -46.748 23.911 1.00 60.29 ? 81 GLN B OE1 1 ATOM 3996 N NE2 . GLN B 1 81 ? 13.517 -47.459 22.019 1.00 60.64 ? 81 GLN B NE2 1 ATOM 3997 N N . ASN B 1 82 ? 11.125 -43.690 27.183 1.00 45.85 ? 82 ASN B N 1 ATOM 3998 C CA . ASN B 1 82 ? 11.367 -43.248 28.551 1.00 45.56 ? 82 ASN B CA 1 ATOM 3999 C C . ASN B 1 82 ? 10.249 -42.433 29.165 1.00 46.39 ? 82 ASN B C 1 ATOM 4000 O O . ASN B 1 82 ? 9.883 -42.619 30.331 1.00 46.21 ? 82 ASN B O 1 ATOM 4001 C CB . ASN B 1 82 ? 12.672 -42.447 28.647 1.00 44.75 ? 82 ASN B CB 1 ATOM 4002 C CG . ASN B 1 82 ? 13.919 -43.296 28.418 1.00 41.15 ? 82 ASN B CG 1 ATOM 4003 O OD1 . ASN B 1 82 ? 13.858 -44.460 28.033 1.00 35.36 ? 82 ASN B OD1 1 ATOM 4004 N ND2 . ASN B 1 82 ? 15.066 -42.682 28.643 1.00 39.51 ? 82 ASN B ND2 1 ATOM 4005 N N . ALA B 1 83 ? 9.717 -41.504 28.386 1.00 47.55 ? 83 ALA B N 1 ATOM 4006 C CA . ALA B 1 83 ? 8.746 -40.550 28.915 1.00 48.26 ? 83 ALA B CA 1 ATOM 4007 C C . ALA B 1 83 ? 7.418 -41.204 29.296 1.00 49.16 ? 83 ALA B C 1 ATOM 4008 O O . ALA B 1 83 ? 7.047 -42.267 28.780 1.00 48.67 ? 83 ALA B O 1 ATOM 4009 C CB . ALA B 1 83 ? 8.542 -39.423 27.945 1.00 48.08 ? 83 ALA B CB 1 ATOM 4010 N N . THR B 1 84 ? 6.719 -40.577 30.231 1.00 50.51 ? 84 THR B N 1 ATOM 4011 C CA . THR B 1 84 ? 5.439 -41.100 30.694 1.00 52.12 ? 84 THR B CA 1 ATOM 4012 C C . THR B 1 84 ? 4.318 -40.126 30.319 1.00 52.99 ? 84 THR B C 1 ATOM 4013 O O . THR B 1 84 ? 3.239 -40.518 29.900 1.00 53.71 ? 84 THR B O 1 ATOM 4014 C CB . THR B 1 84 ? 5.478 -41.321 32.213 1.00 52.32 ? 84 THR B CB 1 ATOM 4015 O OG1 . THR B 1 84 ? 5.731 -40.066 32.870 1.00 51.76 ? 84 THR B OG1 1 ATOM 4016 C CG2 . THR B 1 84 ? 6.579 -42.354 32.595 1.00 51.72 ? 84 THR B CG2 1 ATOM 4017 N N . THR B 1 85 ? 4.597 -38.843 30.466 1.00 53.93 ? 85 THR B N 1 ATOM 4018 C CA . THR B 1 85 ? 3.636 -37.808 30.116 1.00 54.81 ? 85 THR B CA 1 ATOM 4019 C C . THR B 1 85 ? 3.949 -37.146 28.761 1.00 54.88 ? 85 THR B C 1 ATOM 4020 O O . THR B 1 85 ? 4.876 -36.300 28.644 1.00 55.16 ? 85 THR B O 1 ATOM 4021 C CB . THR B 1 85 ? 3.497 -36.687 31.229 1.00 55.11 ? 85 THR B CB 1 ATOM 4022 O OG1 . THR B 1 85 ? 4.719 -36.529 31.984 1.00 55.24 ? 85 THR B OG1 1 ATOM 4023 C CG2 . THR B 1 85 ? 2.360 -37.003 32.156 1.00 55.65 ? 85 THR B CG2 1 ATOM 4024 N N . PHE B 1 86 ? 3.174 -37.507 27.743 1.00 54.29 ? 86 PHE B N 1 ATOM 4025 C CA . PHE B 1 86 ? 3.194 -36.715 26.533 1.00 53.83 ? 86 PHE B CA 1 ATOM 4026 C C . PHE B 1 86 ? 1.929 -35.908 26.502 1.00 53.41 ? 86 PHE B C 1 ATOM 4027 O O . PHE B 1 86 ? 0.932 -36.366 25.948 1.00 53.75 ? 86 PHE B O 1 ATOM 4028 C CB . PHE B 1 86 ? 3.259 -37.590 25.292 1.00 53.81 ? 86 PHE B CB 1 ATOM 4029 C CG . PHE B 1 86 ? 4.470 -38.466 25.215 1.00 53.90 ? 86 PHE B CG 1 ATOM 4030 C CD1 . PHE B 1 86 ? 5.643 -38.006 24.618 1.00 54.00 ? 86 PHE B CD1 1 ATOM 4031 C CD2 . PHE B 1 86 ? 4.424 -39.779 25.702 1.00 53.87 ? 86 PHE B CD2 1 ATOM 4032 C CE1 . PHE B 1 86 ? 6.759 -38.836 24.527 1.00 53.69 ? 86 PHE B CE1 1 ATOM 4033 C CE2 . PHE B 1 86 ? 5.529 -40.618 25.608 1.00 53.96 ? 86 PHE B CE2 1 ATOM 4034 C CZ . PHE B 1 86 ? 6.703 -40.150 25.018 1.00 52.88 ? 86 PHE B CZ 1 ATOM 4035 N N . ASP B 1 87 ? 1.932 -34.730 27.111 1.00 52.83 ? 87 ASP B N 1 ATOM 4036 C CA . ASP B 1 87 ? 0.745 -33.895 26.988 1.00 53.19 ? 87 ASP B CA 1 ATOM 4037 C C . ASP B 1 87 ? 0.931 -32.443 26.580 1.00 52.06 ? 87 ASP B C 1 ATOM 4038 O O . ASP B 1 87 ? 2.053 -31.967 26.489 1.00 52.11 ? 87 ASP B O 1 ATOM 4039 C CB . ASP B 1 87 ? -0.266 -34.095 28.142 1.00 54.50 ? 87 ASP B CB 1 ATOM 4040 C CG . ASP B 1 87 ? 0.255 -33.658 29.496 1.00 57.21 ? 87 ASP B CG 1 ATOM 4041 O OD1 . ASP B 1 87 ? 0.071 -32.473 29.840 1.00 60.44 ? 87 ASP B OD1 1 ATOM 4042 O OD2 . ASP B 1 87 ? 0.778 -34.511 30.256 1.00 60.18 ? 87 ASP B OD2 1 ATOM 4043 N N . GLY B 1 88 ? -0.188 -31.771 26.285 1.00 51.01 ? 88 GLY B N 1 ATOM 4044 C CA . GLY B 1 88 ? -0.195 -30.475 25.574 1.00 49.66 ? 88 GLY B CA 1 ATOM 4045 C C . GLY B 1 88 ? 0.628 -30.515 24.291 1.00 48.47 ? 88 GLY B C 1 ATOM 4046 O O . GLY B 1 88 ? 0.538 -31.461 23.488 1.00 47.97 ? 88 GLY B O 1 ATOM 4047 N N . LYS B 1 89 ? 1.471 -29.494 24.136 1.00 47.71 ? 89 LYS B N 1 ATOM 4048 C CA . LYS B 1 89 ? 2.389 -29.371 22.996 1.00 45.99 ? 89 LYS B CA 1 ATOM 4049 C C . LYS B 1 89 ? 3.284 -30.605 22.761 1.00 44.51 ? 89 LYS B C 1 ATOM 4050 O O . LYS B 1 89 ? 3.829 -30.767 21.679 1.00 44.05 ? 89 LYS B O 1 ATOM 4051 C CB . LYS B 1 89 ? 3.192 -28.066 23.090 1.00 46.39 ? 89 LYS B CB 1 ATOM 4052 C CG . LYS B 1 89 ? 3.856 -27.805 24.428 1.00 47.46 ? 89 LYS B CG 1 ATOM 4053 C CD . LYS B 1 89 ? 4.368 -26.359 24.550 1.00 51.87 ? 89 LYS B CD 1 ATOM 4054 C CE . LYS B 1 89 ? 5.037 -26.142 25.930 1.00 55.50 ? 89 LYS B CE 1 ATOM 4055 N NZ . LYS B 1 89 ? 5.707 -24.814 26.152 1.00 54.87 ? 89 LYS B NZ 1 ATOM 4056 N N . TYR B 1 90 ? 3.376 -31.496 23.743 1.00 42.75 ? 90 TYR B N 1 ATOM 4057 C CA . TYR B 1 90 ? 4.245 -32.666 23.621 1.00 41.29 ? 90 TYR B CA 1 ATOM 4058 C C . TYR B 1 90 ? 3.548 -33.893 23.080 1.00 41.22 ? 90 TYR B C 1 ATOM 4059 O O . TYR B 1 90 ? 4.212 -34.883 22.763 1.00 40.88 ? 90 TYR B O 1 ATOM 4060 C CB . TYR B 1 90 ? 4.874 -33.038 24.981 1.00 40.94 ? 90 TYR B CB 1 ATOM 4061 C CG . TYR B 1 90 ? 5.749 -31.977 25.549 1.00 37.93 ? 90 TYR B CG 1 ATOM 4062 C CD1 . TYR B 1 90 ? 7.104 -31.917 25.209 1.00 36.63 ? 90 TYR B CD1 1 ATOM 4063 C CD2 . TYR B 1 90 ? 5.227 -31.000 26.415 1.00 36.02 ? 90 TYR B CD2 1 ATOM 4064 C CE1 . TYR B 1 90 ? 7.936 -30.921 25.721 1.00 33.15 ? 90 TYR B CE1 1 ATOM 4065 C CE2 . TYR B 1 90 ? 6.045 -30.001 26.942 1.00 35.28 ? 90 TYR B CE2 1 ATOM 4066 C CZ . TYR B 1 90 ? 7.411 -29.984 26.575 1.00 33.48 ? 90 TYR B CZ 1 ATOM 4067 O OH . TYR B 1 90 ? 8.226 -29.040 27.069 1.00 30.82 ? 90 TYR B OH 1 ATOM 4068 N N . ALA B 1 91 ? 2.222 -33.846 22.973 1.00 41.24 ? 91 ALA B N 1 ATOM 4069 C CA . ALA B 1 91 ? 1.437 -35.047 22.685 1.00 41.41 ? 91 ALA B CA 1 ATOM 4070 C C . ALA B 1 91 ? 1.883 -35.782 21.434 1.00 41.37 ? 91 ALA B C 1 ATOM 4071 O O . ALA B 1 91 ? 1.963 -37.035 21.424 1.00 40.47 ? 91 ALA B O 1 ATOM 4072 C CB . ALA B 1 91 ? -0.051 -34.719 22.634 1.00 41.94 ? 91 ALA B CB 1 ATOM 4073 N N . PHE B 1 92 ? 2.247 -34.988 20.419 1.00 42.12 ? 92 PHE B N 1 ATOM 4074 C CA . PHE B 1 92 ? 2.634 -35.491 19.067 1.00 42.70 ? 92 PHE B CA 1 ATOM 4075 C C . PHE B 1 92 ? 3.782 -36.460 19.123 1.00 43.11 ? 92 PHE B C 1 ATOM 4076 O O . PHE B 1 92 ? 3.921 -37.321 18.261 1.00 43.85 ? 92 PHE B O 1 ATOM 4077 C CB . PHE B 1 92 ? 2.977 -34.328 18.110 1.00 42.53 ? 92 PHE B CB 1 ATOM 4078 C CG . PHE B 1 92 ? 4.337 -33.704 18.347 1.00 41.13 ? 92 PHE B CG 1 ATOM 4079 C CD1 . PHE B 1 92 ? 4.495 -32.679 19.274 1.00 39.00 ? 92 PHE B CD1 1 ATOM 4080 C CD2 . PHE B 1 92 ? 5.456 -34.147 17.652 1.00 39.73 ? 92 PHE B CD2 1 ATOM 4081 C CE1 . PHE B 1 92 ? 5.737 -32.111 19.502 1.00 39.33 ? 92 PHE B CE1 1 ATOM 4082 C CE2 . PHE B 1 92 ? 6.724 -33.574 17.878 1.00 39.29 ? 92 PHE B CE2 1 ATOM 4083 C CZ . PHE B 1 92 ? 6.860 -32.562 18.803 1.00 38.36 ? 92 PHE B CZ 1 ATOM 4084 N N . LEU B 1 93 ? 4.604 -36.303 20.155 1.00 44.36 ? 93 LEU B N 1 ATOM 4085 C CA . LEU B 1 93 ? 5.823 -37.077 20.301 1.00 45.15 ? 93 LEU B CA 1 ATOM 4086 C C . LEU B 1 93 ? 5.609 -38.543 20.641 1.00 46.07 ? 93 LEU B C 1 ATOM 4087 O O . LEU B 1 93 ? 6.517 -39.344 20.470 1.00 46.19 ? 93 LEU B O 1 ATOM 4088 C CB . LEU B 1 93 ? 6.752 -36.427 21.318 1.00 44.58 ? 93 LEU B CB 1 ATOM 4089 C CG . LEU B 1 93 ? 7.879 -35.608 20.720 1.00 43.71 ? 93 LEU B CG 1 ATOM 4090 C CD1 . LEU B 1 93 ? 8.569 -34.856 21.845 1.00 44.20 ? 93 LEU B CD1 1 ATOM 4091 C CD2 . LEU B 1 93 ? 8.862 -36.505 19.935 1.00 38.68 ? 93 LEU B CD2 1 ATOM 4092 N N . LYS B 1 94 ? 4.421 -38.913 21.111 1.00 47.85 ? 94 LYS B N 1 ATOM 4093 C CA . LYS B 1 94 ? 4.215 -40.323 21.456 1.00 49.40 ? 94 LYS B CA 1 ATOM 4094 C C . LYS B 1 94 ? 4.274 -41.201 20.214 1.00 49.64 ? 94 LYS B C 1 ATOM 4095 O O . LYS B 1 94 ? 4.831 -42.323 20.244 1.00 49.46 ? 94 LYS B O 1 ATOM 4096 C CB . LYS B 1 94 ? 2.904 -40.576 22.217 1.00 49.93 ? 94 LYS B CB 1 ATOM 4097 C CG . LYS B 1 94 ? 2.871 -42.010 22.789 1.00 52.48 ? 94 LYS B CG 1 ATOM 4098 C CD . LYS B 1 94 ? 1.737 -42.251 23.780 1.00 58.47 ? 94 LYS B CD 1 ATOM 4099 C CE . LYS B 1 94 ? 1.728 -43.718 24.249 1.00 60.36 ? 94 LYS B CE 1 ATOM 4100 N NZ . LYS B 1 94 ? 1.191 -43.847 25.643 1.00 61.92 ? 94 LYS B NZ 1 ATOM 4101 N N . THR B 1 95 ? 3.696 -40.666 19.132 1.00 50.07 ? 95 THR B N 1 ATOM 4102 C CA . THR B 1 95 ? 3.568 -41.388 17.858 1.00 50.33 ? 95 THR B CA 1 ATOM 4103 C C . THR B 1 95 ? 4.527 -40.970 16.756 1.00 49.87 ? 95 THR B C 1 ATOM 4104 O O . THR B 1 95 ? 4.642 -41.689 15.745 1.00 50.47 ? 95 THR B O 1 ATOM 4105 C CB . THR B 1 95 ? 2.151 -41.272 17.287 1.00 50.58 ? 95 THR B CB 1 ATOM 4106 O OG1 . THR B 1 95 ? 1.604 -39.984 17.625 1.00 50.72 ? 95 THR B OG1 1 ATOM 4107 C CG2 . THR B 1 95 ? 1.267 -42.400 17.856 1.00 51.04 ? 95 THR B CG2 1 ATOM 4108 N N . TYR B 1 96 ? 5.201 -39.832 16.928 1.00 48.27 ? 96 TYR B N 1 ATOM 4109 C CA . TYR B 1 96 ? 6.008 -39.314 15.851 1.00 46.69 ? 96 TYR B CA 1 ATOM 4110 C C . TYR B 1 96 ? 6.812 -40.438 15.218 1.00 46.56 ? 96 TYR B C 1 ATOM 4111 O O . TYR B 1 96 ? 7.407 -41.248 15.903 1.00 45.72 ? 96 TYR B O 1 ATOM 4112 C CB . TYR B 1 96 ? 6.900 -38.150 16.283 1.00 46.22 ? 96 TYR B CB 1 ATOM 4113 C CG . TYR B 1 96 ? 7.643 -37.550 15.111 1.00 43.03 ? 96 TYR B CG 1 ATOM 4114 C CD1 . TYR B 1 96 ? 7.113 -36.493 14.415 1.00 41.34 ? 96 TYR B CD1 1 ATOM 4115 C CD2 . TYR B 1 96 ? 8.858 -38.081 14.674 1.00 39.98 ? 96 TYR B CD2 1 ATOM 4116 C CE1 . TYR B 1 96 ? 7.782 -35.945 13.320 1.00 40.72 ? 96 TYR B CE1 1 ATOM 4117 C CE2 . TYR B 1 96 ? 9.524 -37.550 13.587 1.00 39.38 ? 96 TYR B CE2 1 ATOM 4118 C CZ . TYR B 1 96 ? 8.979 -36.474 12.927 1.00 39.09 ? 96 TYR B CZ 1 ATOM 4119 O OH . TYR B 1 96 ? 9.604 -35.942 11.837 1.00 40.03 ? 96 TYR B OH 1 ATOM 4120 N N . ASN B 1 97 ? 6.794 -40.496 13.891 1.00 46.78 ? 97 ASN B N 1 ATOM 4121 C CA . ASN B 1 97 ? 7.441 -41.587 13.186 1.00 47.07 ? 97 ASN B CA 1 ATOM 4122 C C . ASN B 1 97 ? 8.478 -40.984 12.265 1.00 45.91 ? 97 ASN B C 1 ATOM 4123 O O . ASN B 1 97 ? 8.157 -40.418 11.215 1.00 46.18 ? 97 ASN B O 1 ATOM 4124 C CB . ASN B 1 97 ? 6.402 -42.425 12.420 1.00 47.96 ? 97 ASN B CB 1 ATOM 4125 C CG . ASN B 1 97 ? 6.948 -43.768 11.938 1.00 50.98 ? 97 ASN B CG 1 ATOM 4126 O OD1 . ASN B 1 97 ? 8.163 -43.964 11.794 1.00 53.20 ? 97 ASN B OD1 1 ATOM 4127 N ND2 . ASN B 1 97 ? 6.029 -44.712 11.668 1.00 56.03 ? 97 ASN B ND2 1 ATOM 4128 N N . TYR B 1 98 ? 9.729 -41.096 12.685 1.00 44.30 ? 98 TYR B N 1 ATOM 4129 C CA . TYR B 1 98 ? 10.822 -40.505 11.951 1.00 42.05 ? 98 TYR B CA 1 ATOM 4130 C C . TYR B 1 98 ? 10.943 -41.215 10.631 1.00 41.08 ? 98 TYR B C 1 ATOM 4131 O O . TYR B 1 98 ? 11.247 -42.412 10.597 1.00 40.39 ? 98 TYR B O 1 ATOM 4132 C CB . TYR B 1 98 ? 12.133 -40.610 12.727 1.00 41.13 ? 98 TYR B CB 1 ATOM 4133 C CG . TYR B 1 98 ? 13.238 -39.770 12.141 1.00 37.45 ? 98 TYR B CG 1 ATOM 4134 C CD1 . TYR B 1 98 ? 14.102 -40.306 11.177 1.00 36.69 ? 98 TYR B CD1 1 ATOM 4135 C CD2 . TYR B 1 98 ? 13.437 -38.451 12.549 1.00 33.31 ? 98 TYR B CD2 1 ATOM 4136 C CE1 . TYR B 1 98 ? 15.131 -39.546 10.618 1.00 34.53 ? 98 TYR B CE1 1 ATOM 4137 C CE2 . TYR B 1 98 ? 14.482 -37.686 12.010 1.00 30.89 ? 98 TYR B CE2 1 ATOM 4138 C CZ . TYR B 1 98 ? 15.317 -38.245 11.035 1.00 30.91 ? 98 TYR B CZ 1 ATOM 4139 O OH . TYR B 1 98 ? 16.350 -37.542 10.460 1.00 30.92 ? 98 TYR B OH 1 ATOM 4140 N N . SER B 1 99 ? 10.708 -40.462 9.555 1.00 40.18 ? 99 SER B N 1 ATOM 4141 C CA . SER B 1 99 ? 10.876 -41.006 8.202 1.00 39.57 ? 99 SER B CA 1 ATOM 4142 C C . SER B 1 99 ? 11.502 -40.035 7.182 1.00 39.11 ? 99 SER B C 1 ATOM 4143 O O . SER B 1 99 ? 11.410 -40.276 5.959 1.00 39.08 ? 99 SER B O 1 ATOM 4144 C CB . SER B 1 99 ? 9.550 -41.550 7.680 1.00 39.99 ? 99 SER B CB 1 ATOM 4145 O OG . SER B 1 99 ? 8.623 -40.490 7.615 1.00 37.84 ? 99 SER B OG 1 ATOM 4146 N N . LEU B 1 100 ? 12.107 -38.946 7.681 1.00 36.86 ? 100 LEU B N 1 ATOM 4147 C CA . LEU B 1 100 ? 13.063 -38.142 6.885 1.00 35.24 ? 100 LEU B CA 1 ATOM 4148 C C . LEU B 1 100 ? 14.072 -38.986 6.112 1.00 34.10 ? 100 LEU B C 1 ATOM 4149 O O . LEU B 1 100 ? 14.555 -40.039 6.597 1.00 33.99 ? 100 LEU B O 1 ATOM 4150 C CB . LEU B 1 100 ? 13.843 -37.162 7.770 1.00 34.24 ? 100 LEU B CB 1 ATOM 4151 C CG . LEU B 1 100 ? 12.987 -36.169 8.561 1.00 34.86 ? 100 LEU B CG 1 ATOM 4152 C CD1 . LEU B 1 100 ? 13.841 -35.161 9.303 1.00 33.21 ? 100 LEU B CD1 1 ATOM 4153 C CD2 . LEU B 1 100 ? 11.990 -35.462 7.651 1.00 35.76 ? 100 LEU B CD2 1 ATOM 4154 N N . GLY B 1 101 ? 14.409 -38.508 4.909 1.00 32.73 ? 101 GLY B N 1 ATOM 4155 C CA . GLY B 1 101 ? 15.465 -39.120 4.123 1.00 30.28 ? 101 GLY B CA 1 ATOM 4156 C C . GLY B 1 101 ? 16.740 -38.524 4.632 1.00 30.08 ? 101 GLY B C 1 ATOM 4157 O O . GLY B 1 101 ? 16.725 -37.818 5.651 1.00 28.75 ? 101 GLY B O 1 ATOM 4158 N N . ALA B 1 102 ? 17.818 -38.735 3.872 1.00 29.55 ? 102 ALA B N 1 ATOM 4159 C CA . ALA B 1 102 ? 19.163 -38.348 4.268 1.00 29.93 ? 102 ALA B CA 1 ATOM 4160 C C . ALA B 1 102 ? 19.990 -37.715 3.127 1.00 29.99 ? 102 ALA B C 1 ATOM 4161 O O . ALA B 1 102 ? 19.978 -38.219 1.998 1.00 29.61 ? 102 ALA B O 1 ATOM 4162 C CB . ALA B 1 102 ? 19.891 -39.585 4.843 1.00 30.48 ? 102 ALA B CB 1 ATOM 4163 N N . ASP B 1 103 ? 20.710 -36.629 3.445 1.00 29.13 ? 103 ASP B N 1 ATOM 4164 C CA . ASP B 1 103 ? 21.660 -35.925 2.531 1.00 29.43 ? 103 ASP B CA 1 ATOM 4165 C C . ASP B 1 103 ? 21.072 -35.178 1.321 1.00 29.36 ? 103 ASP B C 1 ATOM 4166 O O . ASP B 1 103 ? 21.499 -34.073 1.013 1.00 29.43 ? 103 ASP B O 1 ATOM 4167 C CB . ASP B 1 103 ? 22.786 -36.856 2.071 1.00 30.04 ? 103 ASP B CB 1 ATOM 4168 C CG . ASP B 1 103 ? 23.618 -37.408 3.249 1.00 33.11 ? 103 ASP B CG 1 ATOM 4169 O OD1 . ASP B 1 103 ? 24.200 -36.619 4.027 1.00 34.22 ? 103 ASP B OD1 1 ATOM 4170 O OD2 . ASP B 1 103 ? 23.659 -38.645 3.400 1.00 36.39 ? 103 ASP B OD2 1 ATOM 4171 N N . ASP B 1 104 ? 20.109 -35.808 0.658 1.00 28.61 ? 104 ASP B N 1 ATOM 4172 C CA . ASP B 1 104 ? 19.561 -35.375 -0.614 1.00 29.17 ? 104 ASP B CA 1 ATOM 4173 C C . ASP B 1 104 ? 18.699 -34.153 -0.401 1.00 27.95 ? 104 ASP B C 1 ATOM 4174 O O . ASP B 1 104 ? 18.200 -33.928 0.703 1.00 28.20 ? 104 ASP B O 1 ATOM 4175 C CB . ASP B 1 104 ? 18.668 -36.496 -1.242 1.00 29.59 ? 104 ASP B CB 1 ATOM 4176 C CG . ASP B 1 104 ? 19.377 -37.871 -1.338 1.00 34.02 ? 104 ASP B CG 1 ATOM 4177 O OD1 . ASP B 1 104 ? 20.659 -37.889 -1.443 1.00 36.56 ? 104 ASP B OD1 1 ATOM 4178 O OD2 . ASP B 1 104 ? 18.651 -38.929 -1.335 1.00 34.51 ? 104 ASP B OD2 1 ATOM 4179 N N . LEU B 1 105 ? 18.515 -33.393 -1.465 1.00 26.13 ? 105 LEU B N 1 ATOM 4180 C CA . LEU B 1 105 ? 17.535 -32.323 -1.560 1.00 25.87 ? 105 LEU B CA 1 ATOM 4181 C C . LEU B 1 105 ? 16.104 -32.801 -1.291 1.00 25.41 ? 105 LEU B C 1 ATOM 4182 O O . LEU B 1 105 ? 15.744 -33.874 -1.710 1.00 26.63 ? 105 LEU B O 1 ATOM 4183 C CB . LEU B 1 105 ? 17.608 -31.813 -2.998 1.00 24.60 ? 105 LEU B CB 1 ATOM 4184 C CG . LEU B 1 105 ? 18.161 -30.491 -3.466 1.00 24.76 ? 105 LEU B CG 1 ATOM 4185 C CD1 . LEU B 1 105 ? 19.180 -29.783 -2.540 1.00 25.28 ? 105 LEU B CD1 1 ATOM 4186 C CD2 . LEU B 1 105 ? 18.667 -30.607 -4.917 1.00 20.73 ? 105 LEU B CD2 1 ATOM 4187 N N . THR B 1 106 ? 15.289 -32.018 -0.615 1.00 25.43 ? 106 THR B N 1 ATOM 4188 C CA . THR B 1 106 ? 13.855 -32.345 -0.474 1.00 25.76 ? 106 THR B CA 1 ATOM 4189 C C . THR B 1 106 ? 13.046 -31.788 -1.700 1.00 26.91 ? 106 THR B C 1 ATOM 4190 O O . THR B 1 106 ? 13.568 -30.974 -2.469 1.00 27.79 ? 106 THR B O 1 ATOM 4191 C CB . THR B 1 106 ? 13.334 -31.696 0.747 1.00 25.06 ? 106 THR B CB 1 ATOM 4192 O OG1 . THR B 1 106 ? 13.464 -30.275 0.556 1.00 25.71 ? 106 THR B OG1 1 ATOM 4193 C CG2 . THR B 1 106 ? 14.161 -32.156 2.000 1.00 21.16 ? 106 THR B CG2 1 ATOM 4194 N N . PRO B 1 107 ? 11.790 -32.226 -1.907 1.00 26.90 ? 107 PRO B N 1 ATOM 4195 C CA . PRO B 1 107 ? 11.022 -31.606 -3.003 1.00 25.80 ? 107 PRO B CA 1 ATOM 4196 C C . PRO B 1 107 ? 11.022 -30.093 -2.871 1.00 24.44 ? 107 PRO B C 1 ATOM 4197 O O . PRO B 1 107 ? 11.185 -29.367 -3.842 1.00 24.56 ? 107 PRO B O 1 ATOM 4198 C CB . PRO B 1 107 ? 9.611 -32.194 -2.793 1.00 26.43 ? 107 PRO B CB 1 ATOM 4199 C CG . PRO B 1 107 ? 9.934 -33.669 -2.343 1.00 28.22 ? 107 PRO B CG 1 ATOM 4200 C CD . PRO B 1 107 ? 11.237 -33.540 -1.512 1.00 26.96 ? 107 PRO B CD 1 ATOM 4201 N N . PHE B 1 108 ? 10.861 -29.612 -1.655 1.00 23.52 ? 108 PHE B N 1 ATOM 4202 C CA . PHE B 1 108 ? 10.928 -28.165 -1.399 1.00 22.18 ? 108 PHE B CA 1 ATOM 4203 C C . PHE B 1 108 ? 12.258 -27.534 -1.859 1.00 21.68 ? 108 PHE B C 1 ATOM 4204 O O . PHE B 1 108 ? 12.283 -26.482 -2.459 1.00 20.68 ? 108 PHE B O 1 ATOM 4205 C CB . PHE B 1 108 ? 10.661 -27.887 0.077 1.00 21.27 ? 108 PHE B CB 1 ATOM 4206 C CG . PHE B 1 108 ? 10.736 -26.444 0.446 1.00 21.56 ? 108 PHE B CG 1 ATOM 4207 C CD1 . PHE B 1 108 ? 9.713 -25.560 0.104 1.00 18.49 ? 108 PHE B CD1 1 ATOM 4208 C CD2 . PHE B 1 108 ? 11.856 -25.956 1.096 1.00 21.83 ? 108 PHE B CD2 1 ATOM 4209 C CE1 . PHE B 1 108 ? 9.829 -24.195 0.416 1.00 21.12 ? 108 PHE B CE1 1 ATOM 4210 C CE2 . PHE B 1 108 ? 11.963 -24.594 1.419 1.00 23.80 ? 108 PHE B CE2 1 ATOM 4211 C CZ . PHE B 1 108 ? 10.932 -23.726 1.078 1.00 22.42 ? 108 PHE B CZ 1 ATOM 4212 N N . GLY B 1 109 ? 13.367 -28.183 -1.553 1.00 22.14 ? 109 GLY B N 1 ATOM 4213 C CA . GLY B 1 109 ? 14.673 -27.644 -1.874 1.00 22.28 ? 109 GLY B CA 1 ATOM 4214 C C . GLY B 1 109 ? 14.883 -27.598 -3.365 1.00 23.07 ? 109 GLY B C 1 ATOM 4215 O O . GLY B 1 109 ? 15.533 -26.700 -3.874 1.00 23.42 ? 109 GLY B O 1 ATOM 4216 N N . GLU B 1 110 ? 14.358 -28.612 -4.064 1.00 23.37 ? 110 GLU B N 1 ATOM 4217 C CA . GLU B 1 110 ? 14.349 -28.647 -5.509 1.00 22.28 ? 110 GLU B CA 1 ATOM 4218 C C . GLU B 1 110 ? 13.713 -27.408 -6.114 1.00 21.24 ? 110 GLU B C 1 ATOM 4219 O O . GLU B 1 110 ? 14.305 -26.727 -6.992 1.00 20.79 ? 110 GLU B O 1 ATOM 4220 C CB . GLU B 1 110 ? 13.645 -29.914 -5.964 1.00 23.13 ? 110 GLU B CB 1 ATOM 4221 C CG . GLU B 1 110 ? 14.520 -31.137 -5.663 1.00 25.80 ? 110 GLU B CG 1 ATOM 4222 C CD . GLU B 1 110 ? 13.914 -32.447 -6.134 1.00 27.61 ? 110 GLU B CD 1 ATOM 4223 O OE1 . GLU B 1 110 ? 12.736 -32.533 -6.484 1.00 30.62 ? 110 GLU B OE1 1 ATOM 4224 O OE2 . GLU B 1 110 ? 14.651 -33.408 -6.185 1.00 30.87 ? 110 GLU B OE2 1 ATOM 4225 N N . GLN B 1 111 ? 12.524 -27.120 -5.624 1.00 19.55 ? 111 GLN B N 1 ATOM 4226 C CA . GLN B 1 111 ? 11.746 -26.065 -6.127 1.00 19.72 ? 111 GLN B CA 1 ATOM 4227 C C . GLN B 1 111 ? 12.364 -24.720 -5.795 1.00 20.05 ? 111 GLN B C 1 ATOM 4228 O O . GLN B 1 111 ? 12.159 -23.754 -6.521 1.00 20.19 ? 111 GLN B O 1 ATOM 4229 C CB . GLN B 1 111 ? 10.339 -26.160 -5.554 1.00 20.44 ? 111 GLN B CB 1 ATOM 4230 C CG . GLN B 1 111 ? 9.440 -25.073 -6.105 1.00 22.20 ? 111 GLN B CG 1 ATOM 4231 C CD . GLN B 1 111 ? 9.137 -25.271 -7.591 1.00 25.77 ? 111 GLN B CD 1 ATOM 4232 O OE1 . GLN B 1 111 ? 8.708 -26.365 -8.023 1.00 30.70 ? 111 GLN B OE1 1 ATOM 4233 N NE2 . GLN B 1 111 ? 9.322 -24.211 -8.371 1.00 22.23 ? 111 GLN B NE2 1 ATOM 4234 N N . GLU B 1 112 ? 13.087 -24.631 -4.692 1.00 19.08 ? 112 GLU B N 1 ATOM 4235 C CA . GLU B 1 112 ? 13.725 -23.385 -4.344 1.00 19.76 ? 112 GLU B CA 1 ATOM 4236 C C . GLU B 1 112 ? 14.732 -23.061 -5.453 1.00 19.48 ? 112 GLU B C 1 ATOM 4237 O O . GLU B 1 112 ? 14.959 -21.887 -5.792 1.00 18.06 ? 112 GLU B O 1 ATOM 4238 C CB . GLU B 1 112 ? 14.506 -23.472 -3.011 1.00 19.66 ? 112 GLU B CB 1 ATOM 4239 C CG . GLU B 1 112 ? 13.709 -23.301 -1.717 1.00 19.38 ? 112 GLU B CG 1 ATOM 4240 C CD . GLU B 1 112 ? 14.661 -23.402 -0.480 1.00 23.80 ? 112 GLU B CD 1 ATOM 4241 O OE1 . GLU B 1 112 ? 15.344 -24.444 -0.349 1.00 21.71 ? 112 GLU B OE1 1 ATOM 4242 O OE2 . GLU B 1 112 ? 14.767 -22.427 0.311 1.00 22.80 ? 112 GLU B OE2 1 ATOM 4243 N N . LEU B 1 113 ? 15.389 -24.085 -5.955 1.00 18.99 ? 113 LEU B N 1 ATOM 4244 C CA . LEU B 1 113 ? 16.446 -23.778 -6.906 1.00 20.35 ? 113 LEU B CA 1 ATOM 4245 C C . LEU B 1 113 ? 15.880 -23.563 -8.305 1.00 20.99 ? 113 LEU B C 1 ATOM 4246 O O . LEU B 1 113 ? 16.493 -22.877 -9.085 1.00 22.66 ? 113 LEU B O 1 ATOM 4247 C CB . LEU B 1 113 ? 17.544 -24.817 -6.864 1.00 20.39 ? 113 LEU B CB 1 ATOM 4248 C CG . LEU B 1 113 ? 18.726 -24.648 -5.874 1.00 20.89 ? 113 LEU B CG 1 ATOM 4249 C CD1 . LEU B 1 113 ? 19.924 -23.855 -6.423 1.00 18.99 ? 113 LEU B CD1 1 ATOM 4250 C CD2 . LEU B 1 113 ? 18.262 -24.116 -4.573 1.00 16.98 ? 113 LEU B CD2 1 ATOM 4251 N N . VAL B 1 114 ? 14.693 -24.118 -8.590 1.00 21.15 ? 114 VAL B N 1 ATOM 4252 C CA . VAL B 1 114 ? 13.992 -23.865 -9.857 1.00 20.34 ? 114 VAL B CA 1 ATOM 4253 C C . VAL B 1 114 ? 13.630 -22.395 -9.775 1.00 20.47 ? 114 VAL B C 1 ATOM 4254 O O . VAL B 1 114 ? 14.036 -21.605 -10.638 1.00 20.18 ? 114 VAL B O 1 ATOM 4255 C CB . VAL B 1 114 ? 12.733 -24.733 -10.033 1.00 20.81 ? 114 VAL B CB 1 ATOM 4256 C CG1 . VAL B 1 114 ? 11.771 -24.088 -11.124 1.00 19.50 ? 114 VAL B CG1 1 ATOM 4257 C CG2 . VAL B 1 114 ? 13.091 -26.154 -10.425 1.00 19.93 ? 114 VAL B CG2 1 ATOM 4258 N N . ASN B 1 115 ? 12.917 -22.009 -8.701 1.00 19.27 ? 115 ASN B N 1 ATOM 4259 C CA . ASN B 1 115 ? 12.672 -20.601 -8.421 1.00 18.80 ? 115 ASN B CA 1 ATOM 4260 C C . ASN B 1 115 ? 13.885 -19.657 -8.526 1.00 18.20 ? 115 ASN B C 1 ATOM 4261 O O . ASN B 1 115 ? 13.820 -18.566 -9.098 1.00 18.28 ? 115 ASN B O 1 ATOM 4262 C CB . ASN B 1 115 ? 11.965 -20.438 -7.084 1.00 18.71 ? 115 ASN B CB 1 ATOM 4263 C CG . ASN B 1 115 ? 10.636 -21.156 -7.071 1.00 20.90 ? 115 ASN B CG 1 ATOM 4264 O OD1 . ASN B 1 115 ? 10.240 -21.779 -8.072 1.00 17.47 ? 115 ASN B OD1 1 ATOM 4265 N ND2 . ASN B 1 115 ? 9.958 -21.119 -5.944 1.00 22.30 ? 115 ASN B ND2 1 ATOM 4266 N N . SER B 1 116 ? 14.993 -20.055 -7.957 1.00 17.80 ? 116 SER B N 1 ATOM 4267 C CA . SER B 1 116 ? 16.160 -19.225 -8.050 1.00 18.05 ? 116 SER B CA 1 ATOM 4268 C C . SER B 1 116 ? 16.585 -19.036 -9.538 1.00 17.81 ? 116 SER B C 1 ATOM 4269 O O . SER B 1 116 ? 17.050 -17.969 -9.898 1.00 17.72 ? 116 SER B O 1 ATOM 4270 C CB . SER B 1 116 ? 17.288 -19.826 -7.217 1.00 17.50 ? 116 SER B CB 1 ATOM 4271 O OG . SER B 1 116 ? 18.438 -19.011 -7.262 1.00 16.32 ? 116 SER B OG 1 ATOM 4272 N N . GLY B 1 117 ? 16.501 -20.097 -10.363 1.00 17.80 ? 117 GLY B N 1 ATOM 4273 C CA . GLY B 1 117 ? 16.821 -19.994 -11.797 1.00 17.47 ? 117 GLY B CA 1 ATOM 4274 C C . GLY B 1 117 ? 15.860 -19.045 -12.538 1.00 17.21 ? 117 GLY B C 1 ATOM 4275 O O . GLY B 1 117 ? 16.306 -18.222 -13.328 1.00 16.09 ? 117 GLY B O 1 ATOM 4276 N N . ILE B 1 118 ? 14.554 -19.159 -12.254 1.00 17.06 ? 118 ILE B N 1 ATOM 4277 C CA . ILE B 1 118 ? 13.574 -18.241 -12.747 1.00 17.78 ? 118 ILE B CA 1 ATOM 4278 C C . ILE B 1 118 ? 13.930 -16.809 -12.394 1.00 19.50 ? 118 ILE B C 1 ATOM 4279 O O . ILE B 1 118 ? 14.003 -15.889 -13.277 1.00 19.81 ? 118 ILE B O 1 ATOM 4280 C CB . ILE B 1 118 ? 12.167 -18.576 -12.207 1.00 18.63 ? 118 ILE B CB 1 ATOM 4281 C CG1 . ILE B 1 118 ? 11.819 -20.022 -12.543 1.00 16.51 ? 118 ILE B CG1 1 ATOM 4282 C CG2 . ILE B 1 118 ? 11.159 -17.595 -12.800 1.00 17.20 ? 118 ILE B CG2 1 ATOM 4283 C CD1 . ILE B 1 118 ? 10.446 -20.515 -12.032 1.00 20.09 ? 118 ILE B CD1 1 ATOM 4284 N N . LYS B 1 119 ? 14.179 -16.591 -11.106 1.00 19.79 ? 119 LYS B N 1 ATOM 4285 C CA . LYS B 1 119 ? 14.512 -15.249 -10.637 1.00 19.64 ? 119 LYS B CA 1 ATOM 4286 C C . LYS B 1 119 ? 15.789 -14.716 -11.294 1.00 19.33 ? 119 LYS B C 1 ATOM 4287 O O . LYS B 1 119 ? 15.852 -13.542 -11.687 1.00 20.18 ? 119 LYS B O 1 ATOM 4288 C CB . LYS B 1 119 ? 14.558 -15.201 -9.090 1.00 20.20 ? 119 LYS B CB 1 ATOM 4289 C CG . LYS B 1 119 ? 14.779 -13.784 -8.533 1.00 22.76 ? 119 LYS B CG 1 ATOM 4290 C CD . LYS B 1 119 ? 14.090 -13.569 -7.191 1.00 24.18 ? 119 LYS B CD 1 ATOM 4291 C CE . LYS B 1 119 ? 14.387 -12.153 -6.727 1.00 24.04 ? 119 LYS B CE 1 ATOM 4292 N NZ . LYS B 1 119 ? 14.115 -12.029 -5.291 1.00 23.03 ? 119 LYS B NZ 1 ATOM 4293 N N . PHE B 1 120 ? 16.822 -15.539 -11.428 1.00 17.88 ? 120 PHE B N 1 ATOM 4294 C CA . PHE B 1 120 ? 18.047 -14.992 -12.031 1.00 17.77 ? 120 PHE B CA 1 ATOM 4295 C C . PHE B 1 120 ? 17.818 -14.690 -13.555 1.00 18.65 ? 120 PHE B C 1 ATOM 4296 O O . PHE B 1 120 ? 18.294 -13.682 -14.072 1.00 17.70 ? 120 PHE B O 1 ATOM 4297 C CB . PHE B 1 120 ? 19.182 -15.983 -11.876 1.00 16.45 ? 120 PHE B CB 1 ATOM 4298 C CG . PHE B 1 120 ? 20.500 -15.538 -12.462 1.00 13.67 ? 120 PHE B CG 1 ATOM 4299 C CD1 . PHE B 1 120 ? 21.324 -14.690 -11.778 1.00 15.05 ? 120 PHE B CD1 1 ATOM 4300 C CD2 . PHE B 1 120 ? 20.963 -16.074 -13.635 1.00 14.88 ? 120 PHE B CD2 1 ATOM 4301 C CE1 . PHE B 1 120 ? 22.591 -14.308 -12.302 1.00 15.35 ? 120 PHE B CE1 1 ATOM 4302 C CE2 . PHE B 1 120 ? 22.218 -15.707 -14.176 1.00 17.22 ? 120 PHE B CE2 1 ATOM 4303 C CZ . PHE B 1 120 ? 23.030 -14.824 -13.485 1.00 15.58 ? 120 PHE B CZ 1 ATOM 4304 N N . TYR B 1 121 ? 17.120 -15.597 -14.251 1.00 18.20 ? 121 TYR B N 1 ATOM 4305 C CA . TYR B 1 121 ? 16.775 -15.363 -15.657 1.00 19.21 ? 121 TYR B CA 1 ATOM 4306 C C . TYR B 1 121 ? 16.059 -13.987 -15.842 1.00 18.81 ? 121 TYR B C 1 ATOM 4307 O O . TYR B 1 121 ? 16.479 -13.153 -16.650 1.00 18.33 ? 121 TYR B O 1 ATOM 4308 C CB . TYR B 1 121 ? 15.965 -16.529 -16.286 1.00 18.81 ? 121 TYR B CB 1 ATOM 4309 C CG . TYR B 1 121 ? 15.727 -16.237 -17.758 1.00 20.37 ? 121 TYR B CG 1 ATOM 4310 C CD1 . TYR B 1 121 ? 14.662 -15.397 -18.169 1.00 19.42 ? 121 TYR B CD1 1 ATOM 4311 C CD2 . TYR B 1 121 ? 16.605 -16.725 -18.735 1.00 19.24 ? 121 TYR B CD2 1 ATOM 4312 C CE1 . TYR B 1 121 ? 14.471 -15.071 -19.535 1.00 16.88 ? 121 TYR B CE1 1 ATOM 4313 C CE2 . TYR B 1 121 ? 16.450 -16.390 -20.072 1.00 18.88 ? 121 TYR B CE2 1 ATOM 4314 C CZ . TYR B 1 121 ? 15.394 -15.561 -20.463 1.00 18.46 ? 121 TYR B CZ 1 ATOM 4315 O OH . TYR B 1 121 ? 15.258 -15.240 -21.781 1.00 19.15 ? 121 TYR B OH 1 ATOM 4316 N N . GLN B 1 122 ? 15.026 -13.752 -15.058 1.00 19.34 ? 122 GLN B N 1 ATOM 4317 C CA . GLN B 1 122 ? 14.247 -12.545 -15.148 1.00 20.78 ? 122 GLN B CA 1 ATOM 4318 C C . GLN B 1 122 ? 15.000 -11.280 -14.795 1.00 21.56 ? 122 GLN B C 1 ATOM 4319 O O . GLN B 1 122 ? 14.914 -10.277 -15.513 1.00 21.94 ? 122 GLN B O 1 ATOM 4320 C CB . GLN B 1 122 ? 13.013 -12.650 -14.257 1.00 21.87 ? 122 GLN B CB 1 ATOM 4321 C CG . GLN B 1 122 ? 12.184 -13.849 -14.602 1.00 25.57 ? 122 GLN B CG 1 ATOM 4322 C CD . GLN B 1 122 ? 10.800 -13.801 -14.001 1.00 35.13 ? 122 GLN B CD 1 ATOM 4323 O OE1 . GLN B 1 122 ? 10.617 -13.719 -12.765 1.00 37.78 ? 122 GLN B OE1 1 ATOM 4324 N NE2 . GLN B 1 122 ? 9.795 -13.889 -14.880 1.00 38.14 ? 122 GLN B NE2 1 ATOM 4325 N N . ARG B 1 123 ? 15.705 -11.296 -13.680 1.00 21.27 ? 123 ARG B N 1 ATOM 4326 C CA . ARG B 1 123 ? 16.391 -10.114 -13.224 1.00 21.26 ? 123 ARG B CA 1 ATOM 4327 C C . ARG B 1 123 ? 17.389 -9.601 -14.293 1.00 20.46 ? 123 ARG B C 1 ATOM 4328 O O . ARG B 1 123 ? 17.565 -8.412 -14.467 1.00 19.35 ? 123 ARG B O 1 ATOM 4329 C CB . ARG B 1 123 ? 17.128 -10.406 -11.874 1.00 21.65 ? 123 ARG B CB 1 ATOM 4330 C CG . ARG B 1 123 ? 17.836 -9.180 -11.261 1.00 22.59 ? 123 ARG B CG 1 ATOM 4331 C CD . ARG B 1 123 ? 18.515 -9.438 -9.862 1.00 23.49 ? 123 ARG B CD 1 ATOM 4332 N NE . ARG B 1 123 ? 19.401 -8.311 -9.576 1.00 22.78 ? 123 ARG B NE 1 ATOM 4333 C CZ . ARG B 1 123 ? 19.021 -7.188 -8.954 1.00 22.40 ? 123 ARG B CZ 1 ATOM 4334 N NH1 . ARG B 1 123 ? 17.788 -7.040 -8.446 1.00 19.72 ? 123 ARG B NH1 1 ATOM 4335 N NH2 . ARG B 1 123 ? 19.896 -6.204 -8.815 1.00 17.04 ? 123 ARG B NH2 1 ATOM 4336 N N . TYR B 1 124 ? 18.091 -10.512 -14.947 1.00 20.78 ? 124 TYR B N 1 ATOM 4337 C CA . TYR B 1 124 ? 19.131 -10.133 -15.920 1.00 20.59 ? 124 TYR B CA 1 ATOM 4338 C C . TYR B 1 124 ? 18.719 -10.512 -17.379 1.00 21.30 ? 124 TYR B C 1 ATOM 4339 O O . TYR B 1 124 ? 19.580 -10.708 -18.265 1.00 19.59 ? 124 TYR B O 1 ATOM 4340 C CB . TYR B 1 124 ? 20.456 -10.809 -15.523 1.00 20.10 ? 124 TYR B CB 1 ATOM 4341 C CG . TYR B 1 124 ? 20.888 -10.416 -14.126 1.00 21.94 ? 124 TYR B CG 1 ATOM 4342 C CD1 . TYR B 1 124 ? 21.275 -9.102 -13.847 1.00 19.62 ? 124 TYR B CD1 1 ATOM 4343 C CD2 . TYR B 1 124 ? 20.887 -11.356 -13.067 1.00 18.60 ? 124 TYR B CD2 1 ATOM 4344 C CE1 . TYR B 1 124 ? 21.616 -8.712 -12.556 1.00 21.71 ? 124 TYR B CE1 1 ATOM 4345 C CE2 . TYR B 1 124 ? 21.266 -10.982 -11.784 1.00 16.90 ? 124 TYR B CE2 1 ATOM 4346 C CZ . TYR B 1 124 ? 21.608 -9.673 -11.530 1.00 21.00 ? 124 TYR B CZ 1 ATOM 4347 O OH . TYR B 1 124 ? 21.968 -9.269 -10.279 1.00 20.46 ? 124 TYR B OH 1 ATOM 4348 N N . GLU B 1 125 ? 17.394 -10.605 -17.592 1.00 22.30 ? 125 GLU B N 1 ATOM 4349 C CA . GLU B 1 125 ? 16.768 -10.884 -18.918 1.00 23.26 ? 125 GLU B CA 1 ATOM 4350 C C . GLU B 1 125 ? 17.391 -10.147 -20.129 1.00 22.93 ? 125 GLU B C 1 ATOM 4351 O O . GLU B 1 125 ? 17.467 -10.719 -21.241 1.00 23.04 ? 125 GLU B O 1 ATOM 4352 C CB . GLU B 1 125 ? 15.245 -10.635 -18.870 1.00 22.91 ? 125 GLU B CB 1 ATOM 4353 C CG . GLU B 1 125 ? 14.455 -11.227 -20.061 1.00 23.75 ? 125 GLU B CG 1 ATOM 4354 C CD . GLU B 1 125 ? 14.489 -10.335 -21.329 1.00 25.31 ? 125 GLU B CD 1 ATOM 4355 O OE1 . GLU B 1 125 ? 14.598 -9.075 -21.237 1.00 19.54 ? 125 GLU B OE1 1 ATOM 4356 O OE2 . GLU B 1 125 ? 14.398 -10.940 -22.427 1.00 25.30 ? 125 GLU B OE2 1 ATOM 4357 N N . SER B 1 126 ? 17.855 -8.909 -19.935 1.00 22.26 ? 126 SER B N 1 ATOM 4358 C CA . SER B 1 126 ? 18.363 -8.226 -21.084 1.00 22.23 ? 126 SER B CA 1 ATOM 4359 C C . SER B 1 126 ? 19.711 -8.814 -21.559 1.00 21.42 ? 126 SER B C 1 ATOM 4360 O O . SER B 1 126 ? 20.135 -8.562 -22.701 1.00 20.70 ? 126 SER B O 1 ATOM 4361 C CB . SER B 1 126 ? 18.233 -6.696 -20.993 1.00 23.35 ? 126 SER B CB 1 ATOM 4362 O OG . SER B 1 126 ? 19.348 -6.136 -20.356 1.00 29.11 ? 126 SER B OG 1 ATOM 4363 N N . LEU B 1 127 ? 20.296 -9.689 -20.726 1.00 20.01 ? 127 LEU B N 1 ATOM 4364 C CA . LEU B 1 127 ? 21.437 -10.541 -21.088 1.00 18.26 ? 127 LEU B CA 1 ATOM 4365 C C . LEU B 1 127 ? 21.136 -12.027 -21.156 1.00 19.49 ? 127 LEU B C 1 ATOM 4366 O O . LEU B 1 127 ? 21.782 -12.749 -21.936 1.00 20.06 ? 127 LEU B O 1 ATOM 4367 C CB . LEU B 1 127 ? 22.561 -10.386 -20.071 1.00 17.50 ? 127 LEU B CB 1 ATOM 4368 C CG . LEU B 1 127 ? 22.856 -8.899 -19.758 1.00 18.21 ? 127 LEU B CG 1 ATOM 4369 C CD1 . LEU B 1 127 ? 23.672 -8.736 -18.473 1.00 16.29 ? 127 LEU B CD1 1 ATOM 4370 C CD2 . LEU B 1 127 ? 23.483 -8.128 -20.931 1.00 14.92 ? 127 LEU B CD2 1 ATOM 4371 N N . THR B 1 128 ? 20.225 -12.526 -20.305 1.00 18.77 ? 128 THR B N 1 ATOM 4372 C CA . THR B 1 128 ? 19.980 -13.942 -20.267 1.00 19.22 ? 128 THR B CA 1 ATOM 4373 C C . THR B 1 128 ? 19.219 -14.397 -21.558 1.00 20.73 ? 128 THR B C 1 ATOM 4374 O O . THR B 1 128 ? 19.125 -15.606 -21.866 1.00 19.24 ? 128 THR B O 1 ATOM 4375 C CB . THR B 1 128 ? 19.182 -14.334 -18.972 1.00 19.80 ? 128 THR B CB 1 ATOM 4376 O OG1 . THR B 1 128 ? 17.995 -13.525 -18.863 1.00 20.03 ? 128 THR B OG1 1 ATOM 4377 C CG2 . THR B 1 128 ? 20.041 -14.088 -17.691 1.00 19.28 ? 128 THR B CG2 1 ATOM 4378 N N . ARG B 1 129 ? 18.626 -13.427 -22.278 1.00 21.24 ? 129 ARG B N 1 ATOM 4379 C CA . ARG B 1 129 ? 17.922 -13.778 -23.500 1.00 22.09 ? 129 ARG B CA 1 ATOM 4380 C C . ARG B 1 129 ? 18.826 -14.364 -24.582 1.00 22.29 ? 129 ARG B C 1 ATOM 4381 O O . ARG B 1 129 ? 18.383 -15.184 -25.353 1.00 22.44 ? 129 ARG B O 1 ATOM 4382 C CB . ARG B 1 129 ? 17.127 -12.621 -24.024 1.00 21.70 ? 129 ARG B CB 1 ATOM 4383 C CG . ARG B 1 129 ? 17.922 -11.447 -24.566 1.00 22.20 ? 129 ARG B CG 1 ATOM 4384 C CD . ARG B 1 129 ? 16.969 -10.335 -24.228 1.00 25.15 ? 129 ARG B CD 1 ATOM 4385 N NE . ARG B 1 129 ? 17.008 -9.268 -25.146 1.00 23.94 ? 129 ARG B NE 1 ATOM 4386 C CZ . ARG B 1 129 ? 16.287 -8.167 -25.036 1.00 24.97 ? 129 ARG B CZ 1 ATOM 4387 N NH1 . ARG B 1 129 ? 15.451 -7.929 -23.985 1.00 21.65 ? 129 ARG B NH1 1 ATOM 4388 N NH2 . ARG B 1 129 ? 16.445 -7.274 -26.002 1.00 20.51 ? 129 ARG B NH2 1 ATOM 4389 N N . ASN B 1 130 ? 20.090 -13.985 -24.611 1.00 22.55 ? 130 ASN B N 1 ATOM 4390 C CA . ASN B 1 130 ? 20.968 -14.511 -25.665 1.00 23.74 ? 130 ASN B CA 1 ATOM 4391 C C . ASN B 1 130 ? 22.374 -14.927 -25.199 1.00 23.37 ? 130 ASN B C 1 ATOM 4392 O O . ASN B 1 130 ? 23.241 -15.265 -26.014 1.00 23.04 ? 130 ASN B O 1 ATOM 4393 C CB . ASN B 1 130 ? 21.097 -13.498 -26.814 1.00 23.76 ? 130 ASN B CB 1 ATOM 4394 C CG . ASN B 1 130 ? 21.662 -12.131 -26.347 1.00 25.50 ? 130 ASN B CG 1 ATOM 4395 O OD1 . ASN B 1 130 ? 22.037 -11.948 -25.184 1.00 25.34 ? 130 ASN B OD1 1 ATOM 4396 N ND2 . ASN B 1 130 ? 21.687 -11.160 -27.255 1.00 26.74 ? 130 ASN B ND2 1 ATOM 4397 N N . ILE B 1 131 ? 22.606 -14.911 -23.881 1.00 23.76 ? 131 ILE B N 1 ATOM 4398 C CA . ILE B 1 131 ? 23.913 -15.341 -23.334 1.00 22.58 ? 131 ILE B CA 1 ATOM 4399 C C . ILE B 1 131 ? 23.737 -16.536 -22.401 1.00 22.72 ? 131 ILE B C 1 ATOM 4400 O O . ILE B 1 131 ? 22.965 -16.492 -21.441 1.00 22.55 ? 131 ILE B O 1 ATOM 4401 C CB . ILE B 1 131 ? 24.693 -14.167 -22.693 1.00 23.17 ? 131 ILE B CB 1 ATOM 4402 C CG1 . ILE B 1 131 ? 25.145 -13.208 -23.794 1.00 22.10 ? 131 ILE B CG1 1 ATOM 4403 C CG2 . ILE B 1 131 ? 25.980 -14.668 -22.034 1.00 20.76 ? 131 ILE B CG2 1 ATOM 4404 C CD1 . ILE B 1 131 ? 25.349 -11.814 -23.411 1.00 22.27 ? 131 ILE B CD1 1 ATOM 4405 N N . VAL B 1 132 ? 24.391 -17.631 -22.754 1.00 22.20 ? 132 VAL B N 1 ATOM 4406 C CA . VAL B 1 132 ? 24.339 -18.857 -21.950 1.00 21.33 ? 132 VAL B CA 1 ATOM 4407 C C . VAL B 1 132 ? 25.415 -18.742 -20.850 1.00 20.58 ? 132 VAL B C 1 ATOM 4408 O O . VAL B 1 132 ? 26.624 -18.643 -21.144 1.00 19.92 ? 132 VAL B O 1 ATOM 4409 C CB . VAL B 1 132 ? 24.544 -20.173 -22.828 1.00 21.46 ? 132 VAL B CB 1 ATOM 4410 C CG1 . VAL B 1 132 ? 24.473 -21.451 -21.980 1.00 19.89 ? 132 VAL B CG1 1 ATOM 4411 C CG2 . VAL B 1 132 ? 23.537 -20.213 -23.991 1.00 22.53 ? 132 VAL B CG2 1 ATOM 4412 N N . PRO B 1 133 ? 24.973 -18.720 -19.584 1.00 20.19 ? 133 PRO B N 1 ATOM 4413 C CA . PRO B 1 133 ? 25.913 -18.658 -18.442 1.00 19.75 ? 133 PRO B CA 1 ATOM 4414 C C . PRO B 1 133 ? 26.975 -19.759 -18.472 1.00 18.88 ? 133 PRO B C 1 ATOM 4415 O O . PRO B 1 133 ? 26.707 -20.872 -18.953 1.00 18.26 ? 133 PRO B O 1 ATOM 4416 C CB . PRO B 1 133 ? 24.999 -18.891 -17.256 1.00 19.33 ? 133 PRO B CB 1 ATOM 4417 C CG . PRO B 1 133 ? 23.638 -18.268 -17.696 1.00 19.61 ? 133 PRO B CG 1 ATOM 4418 C CD . PRO B 1 133 ? 23.554 -18.785 -19.134 1.00 19.70 ? 133 PRO B CD 1 ATOM 4419 N N . PHE B 1 134 ? 28.194 -19.440 -18.046 1.00 16.93 ? 134 PHE B N 1 ATOM 4420 C CA . PHE B 1 134 ? 29.144 -20.487 -17.851 1.00 17.02 ? 134 PHE B CA 1 ATOM 4421 C C . PHE B 1 134 ? 28.953 -20.931 -16.379 1.00 17.10 ? 134 PHE B C 1 ATOM 4422 O O . PHE B 1 134 ? 28.872 -20.074 -15.457 1.00 15.65 ? 134 PHE B O 1 ATOM 4423 C CB . PHE B 1 134 ? 30.580 -20.039 -18.086 1.00 15.66 ? 134 PHE B CB 1 ATOM 4424 C CG . PHE B 1 134 ? 31.565 -21.150 -17.902 1.00 18.31 ? 134 PHE B CG 1 ATOM 4425 C CD1 . PHE B 1 134 ? 31.775 -22.078 -18.919 1.00 17.77 ? 134 PHE B CD1 1 ATOM 4426 C CD2 . PHE B 1 134 ? 32.304 -21.273 -16.725 1.00 21.01 ? 134 PHE B CD2 1 ATOM 4427 C CE1 . PHE B 1 134 ? 32.701 -23.101 -18.762 1.00 21.64 ? 134 PHE B CE1 1 ATOM 4428 C CE2 . PHE B 1 134 ? 33.222 -22.308 -16.543 1.00 19.09 ? 134 PHE B CE2 1 ATOM 4429 C CZ . PHE B 1 134 ? 33.420 -23.232 -17.559 1.00 21.23 ? 134 PHE B CZ 1 ATOM 4430 N N . ILE B 1 135 ? 28.858 -22.246 -16.176 1.00 17.36 ? 135 ILE B N 1 ATOM 4431 C CA . ILE B 1 135 ? 28.358 -22.792 -14.895 1.00 17.97 ? 135 ILE B CA 1 ATOM 4432 C C . ILE B 1 135 ? 29.252 -23.783 -14.203 1.00 18.11 ? 135 ILE B C 1 ATOM 4433 O O . ILE B 1 135 ? 29.612 -24.786 -14.799 1.00 19.49 ? 135 ILE B O 1 ATOM 4434 C CB . ILE B 1 135 ? 26.959 -23.406 -15.042 1.00 18.26 ? 135 ILE B CB 1 ATOM 4435 C CG1 . ILE B 1 135 ? 26.012 -22.325 -15.536 1.00 17.62 ? 135 ILE B CG1 1 ATOM 4436 C CG2 . ILE B 1 135 ? 26.474 -24.034 -13.666 1.00 16.75 ? 135 ILE B CG2 1 ATOM 4437 C CD1 . ILE B 1 135 ? 24.539 -22.724 -15.469 1.00 18.14 ? 135 ILE B CD1 1 ATOM 4438 N N . ARG B 1 136 ? 29.564 -23.534 -12.925 1.00 17.61 ? 136 ARG B N 1 ATOM 4439 C CA . ARG B 1 136 ? 30.317 -24.497 -12.124 1.00 17.07 ? 136 ARG B CA 1 ATOM 4440 C C . ARG B 1 136 ? 29.590 -25.038 -10.903 1.00 16.82 ? 136 ARG B C 1 ATOM 4441 O O . ARG B 1 136 ? 28.705 -24.422 -10.358 1.00 16.21 ? 136 ARG B O 1 ATOM 4442 C CB . ARG B 1 136 ? 31.684 -23.969 -11.760 1.00 17.93 ? 136 ARG B CB 1 ATOM 4443 C CG . ARG B 1 136 ? 32.534 -23.640 -12.978 1.00 16.99 ? 136 ARG B CG 1 ATOM 4444 C CD . ARG B 1 136 ? 33.895 -23.033 -12.541 1.00 19.84 ? 136 ARG B CD 1 ATOM 4445 N NE . ARG B 1 136 ? 33.714 -21.951 -11.553 1.00 20.46 ? 136 ARG B NE 1 ATOM 4446 C CZ . ARG B 1 136 ? 34.732 -21.391 -10.882 1.00 18.82 ? 136 ARG B CZ 1 ATOM 4447 N NH1 . ARG B 1 136 ? 35.972 -21.789 -11.124 1.00 17.02 ? 136 ARG B NH1 1 ATOM 4448 N NH2 . ARG B 1 136 ? 34.522 -20.397 -10.008 1.00 15.06 ? 136 ARG B NH2 1 ATOM 4449 N N . SER B 1 137 ? 29.942 -26.241 -10.500 1.00 17.99 ? 137 SER B N 1 ATOM 4450 C CA . SER B 1 137 ? 29.338 -26.768 -9.299 1.00 20.00 ? 137 SER B CA 1 ATOM 4451 C C . SER B 1 137 ? 30.336 -27.583 -8.534 1.00 20.14 ? 137 SER B C 1 ATOM 4452 O O . SER B 1 137 ? 31.116 -28.300 -9.135 1.00 20.57 ? 137 SER B O 1 ATOM 4453 C CB . SER B 1 137 ? 28.102 -27.620 -9.587 1.00 19.95 ? 137 SER B CB 1 ATOM 4454 O OG . SER B 1 137 ? 27.789 -28.400 -8.446 1.00 20.66 ? 137 SER B OG 1 ATOM 4455 N N . SER B 1 138 ? 30.319 -27.455 -7.206 1.00 20.58 ? 138 SER B N 1 ATOM 4456 C CA . SER B 1 138 ? 31.193 -28.288 -6.352 1.00 22.10 ? 138 SER B CA 1 ATOM 4457 C C . SER B 1 138 ? 30.691 -29.724 -6.447 1.00 22.33 ? 138 SER B C 1 ATOM 4458 O O . SER B 1 138 ? 29.493 -29.945 -6.575 1.00 20.31 ? 138 SER B O 1 ATOM 4459 C CB . SER B 1 138 ? 31.174 -27.827 -4.877 1.00 22.47 ? 138 SER B CB 1 ATOM 4460 O OG . SER B 1 138 ? 32.176 -28.510 -4.121 1.00 23.49 ? 138 SER B OG 1 ATOM 4461 N N . GLY B 1 139 ? 31.591 -30.693 -6.343 1.00 23.23 ? 139 GLY B N 1 ATOM 4462 C CA . GLY B 1 139 ? 31.138 -32.076 -6.555 1.00 24.56 ? 139 GLY B CA 1 ATOM 4463 C C . GLY B 1 139 ? 30.500 -32.715 -5.333 1.00 25.99 ? 139 GLY B C 1 ATOM 4464 O O . GLY B 1 139 ? 31.188 -33.397 -4.534 1.00 28.44 ? 139 GLY B O 1 ATOM 4465 N N . SER B 1 140 ? 29.212 -32.502 -5.151 1.00 25.07 ? 140 SER B N 1 ATOM 4466 C CA . SER B 1 140 ? 28.452 -33.139 -4.059 1.00 23.68 ? 140 SER B CA 1 ATOM 4467 C C . SER B 1 140 ? 27.093 -33.318 -4.640 1.00 23.03 ? 140 SER B C 1 ATOM 4468 O O . SER B 1 140 ? 26.594 -32.387 -5.285 1.00 21.58 ? 140 SER B O 1 ATOM 4469 C CB . SER B 1 140 ? 28.350 -32.190 -2.866 1.00 24.28 ? 140 SER B CB 1 ATOM 4470 O OG . SER B 1 140 ? 27.224 -32.484 -2.036 1.00 24.05 ? 140 SER B OG 1 ATOM 4471 N N . SER B 1 141 ? 26.477 -34.491 -4.443 1.00 22.66 ? 141 SER B N 1 ATOM 4472 C CA . SER B 1 141 ? 25.206 -34.775 -5.140 1.00 23.21 ? 141 SER B CA 1 ATOM 4473 C C . SER B 1 141 ? 24.233 -33.653 -5.009 1.00 21.39 ? 141 SER B C 1 ATOM 4474 O O . SER B 1 141 ? 23.606 -33.331 -5.972 1.00 22.81 ? 141 SER B O 1 ATOM 4475 C CB . SER B 1 141 ? 24.506 -36.014 -4.602 1.00 23.07 ? 141 SER B CB 1 ATOM 4476 O OG . SER B 1 141 ? 25.405 -37.055 -4.722 1.00 31.20 ? 141 SER B OG 1 ATOM 4477 N N . ARG B 1 142 ? 24.054 -33.121 -3.810 1.00 19.87 ? 142 ARG B N 1 ATOM 4478 C CA . ARG B 1 142 ? 22.979 -32.135 -3.566 1.00 19.30 ? 142 ARG B CA 1 ATOM 4479 C C . ARG B 1 142 ? 23.322 -30.775 -4.206 1.00 18.60 ? 142 ARG B C 1 ATOM 4480 O O . ARG B 1 142 ? 22.453 -29.963 -4.474 1.00 18.94 ? 142 ARG B O 1 ATOM 4481 C CB . ARG B 1 142 ? 22.674 -31.989 -2.059 1.00 19.14 ? 142 ARG B CB 1 ATOM 4482 C CG . ARG B 1 142 ? 23.892 -31.538 -1.153 1.00 19.05 ? 142 ARG B CG 1 ATOM 4483 C CD . ARG B 1 142 ? 23.427 -31.144 0.306 1.00 21.45 ? 142 ARG B CD 1 ATOM 4484 N NE . ARG B 1 142 ? 24.548 -30.970 1.238 1.00 23.95 ? 142 ARG B NE 1 ATOM 4485 C CZ . ARG B 1 142 ? 25.179 -31.977 1.866 1.00 24.74 ? 142 ARG B CZ 1 ATOM 4486 N NH1 . ARG B 1 142 ? 24.794 -33.219 1.662 1.00 22.03 ? 142 ARG B NH1 1 ATOM 4487 N NH2 . ARG B 1 142 ? 26.227 -31.744 2.674 1.00 21.17 ? 142 ARG B NH2 1 ATOM 4488 N N . VAL B 1 143 ? 24.599 -30.546 -4.473 1.00 18.33 ? 143 VAL B N 1 ATOM 4489 C CA . VAL B 1 143 ? 25.039 -29.285 -5.015 1.00 19.00 ? 143 VAL B CA 1 ATOM 4490 C C . VAL B 1 143 ? 24.769 -29.281 -6.524 1.00 20.11 ? 143 VAL B C 1 ATOM 4491 O O . VAL B 1 143 ? 24.072 -28.379 -7.045 1.00 20.20 ? 143 VAL B O 1 ATOM 4492 C CB . VAL B 1 143 ? 26.497 -28.945 -4.635 1.00 18.74 ? 143 VAL B CB 1 ATOM 4493 C CG1 . VAL B 1 143 ? 26.908 -27.546 -5.202 1.00 16.62 ? 143 VAL B CG1 1 ATOM 4494 C CG2 . VAL B 1 143 ? 26.605 -28.848 -3.144 1.00 18.86 ? 143 VAL B CG2 1 ATOM 4495 N N . ILE B 1 144 ? 25.236 -30.363 -7.161 1.00 19.85 ? 144 ILE B N 1 ATOM 4496 C CA . ILE B 1 144 ? 24.930 -30.756 -8.518 1.00 19.52 ? 144 ILE B CA 1 ATOM 4497 C C . ILE B 1 144 ? 23.446 -30.795 -8.835 1.00 19.64 ? 144 ILE B C 1 ATOM 4498 O O . ILE B 1 144 ? 23.002 -30.108 -9.765 1.00 20.72 ? 144 ILE B O 1 ATOM 4499 C CB . ILE B 1 144 ? 25.614 -32.088 -8.865 1.00 19.72 ? 144 ILE B CB 1 ATOM 4500 C CG1 . ILE B 1 144 ? 27.134 -31.877 -8.935 1.00 19.82 ? 144 ILE B CG1 1 ATOM 4501 C CG2 . ILE B 1 144 ? 25.110 -32.583 -10.164 1.00 20.05 ? 144 ILE B CG2 1 ATOM 4502 C CD1 . ILE B 1 144 ? 27.924 -33.254 -8.758 1.00 25.66 ? 144 ILE B CD1 1 ATOM 4503 N N . ALA B 1 145 ? 22.662 -31.548 -8.080 1.00 18.13 ? 145 ALA B N 1 ATOM 4504 C CA . ALA B 1 145 ? 21.219 -31.570 -8.353 1.00 18.15 ? 145 ALA B CA 1 ATOM 4505 C C . ALA B 1 145 ? 20.653 -30.168 -8.338 1.00 16.94 ? 145 ALA B C 1 ATOM 4506 O O . ALA B 1 145 ? 19.729 -29.829 -9.106 1.00 18.17 ? 145 ALA B O 1 ATOM 4507 C CB . ALA B 1 145 ? 20.455 -32.482 -7.348 1.00 16.84 ? 145 ALA B CB 1 ATOM 4508 N N . SER B 1 146 ? 21.223 -29.343 -7.479 1.00 16.97 ? 146 SER B N 1 ATOM 4509 C CA . SER B 1 146 ? 20.780 -27.979 -7.329 1.00 16.94 ? 146 SER B CA 1 ATOM 4510 C C . SER B 1 146 ? 21.192 -27.148 -8.560 1.00 17.28 ? 146 SER B C 1 ATOM 4511 O O . SER B 1 146 ? 20.352 -26.461 -9.110 1.00 17.36 ? 146 SER B O 1 ATOM 4512 C CB . SER B 1 146 ? 21.358 -27.334 -6.058 1.00 16.80 ? 146 SER B CB 1 ATOM 4513 O OG . SER B 1 146 ? 20.872 -27.949 -4.924 1.00 20.73 ? 146 SER B OG 1 ATOM 4514 N N . GLY B 1 147 ? 22.469 -27.191 -8.964 1.00 16.63 ? 147 GLY B N 1 ATOM 4515 C CA . GLY B 1 147 ? 22.841 -26.649 -10.275 1.00 17.54 ? 147 GLY B CA 1 ATOM 4516 C C . GLY B 1 147 ? 21.757 -26.998 -11.326 1.00 18.51 ? 147 GLY B C 1 ATOM 4517 O O . GLY B 1 147 ? 21.183 -26.101 -11.996 1.00 19.23 ? 147 GLY B O 1 ATOM 4518 N N . LYS B 1 148 ? 21.421 -28.280 -11.457 1.00 18.08 ? 148 LYS B N 1 ATOM 4519 C CA . LYS B 1 148 ? 20.495 -28.691 -12.517 1.00 17.61 ? 148 LYS B CA 1 ATOM 4520 C C . LYS B 1 148 ? 19.078 -28.167 -12.330 1.00 18.18 ? 148 LYS B C 1 ATOM 4521 O O . LYS B 1 148 ? 18.441 -27.842 -13.326 1.00 20.25 ? 148 LYS B O 1 ATOM 4522 C CB . LYS B 1 148 ? 20.534 -30.232 -12.701 1.00 17.94 ? 148 LYS B CB 1 ATOM 4523 C CG . LYS B 1 148 ? 21.896 -30.726 -13.275 1.00 16.62 ? 148 LYS B CG 1 ATOM 4524 C CD . LYS B 1 148 ? 22.033 -32.238 -13.152 1.00 23.04 ? 148 LYS B CD 1 ATOM 4525 C CE . LYS B 1 148 ? 23.337 -32.682 -13.784 1.00 24.30 ? 148 LYS B CE 1 ATOM 4526 N NZ . LYS B 1 148 ? 23.867 -33.944 -13.197 1.00 23.06 ? 148 LYS B NZ 1 ATOM 4527 N N . LYS B 1 149 ? 18.563 -28.069 -11.096 1.00 18.23 ? 149 LYS B N 1 ATOM 4528 C CA . LYS B 1 149 ? 17.259 -27.482 -10.893 1.00 18.53 ? 149 LYS B CA 1 ATOM 4529 C C . LYS B 1 149 ? 17.265 -26.012 -11.223 1.00 19.13 ? 149 LYS B C 1 ATOM 4530 O O . LYS B 1 149 ? 16.251 -25.446 -11.684 1.00 19.77 ? 149 LYS B O 1 ATOM 4531 C CB . LYS B 1 149 ? 16.728 -27.680 -9.459 1.00 18.75 ? 149 LYS B CB 1 ATOM 4532 C CG . LYS B 1 149 ? 16.399 -29.183 -9.153 1.00 17.90 ? 149 LYS B CG 1 ATOM 4533 C CD . LYS B 1 149 ? 14.989 -29.454 -9.628 1.00 16.97 ? 149 LYS B CD 1 ATOM 4534 C CE . LYS B 1 149 ? 14.680 -30.932 -9.812 1.00 17.07 ? 149 LYS B CE 1 ATOM 4535 N NZ . LYS B 1 149 ? 13.373 -31.014 -10.550 1.00 19.49 ? 149 LYS B NZ 1 ATOM 4536 N N . PHE B 1 150 ? 18.368 -25.357 -10.950 1.00 18.72 ? 150 PHE B N 1 ATOM 4537 C CA . PHE B 1 150 ? 18.429 -23.915 -11.212 1.00 18.71 ? 150 PHE B CA 1 ATOM 4538 C C . PHE B 1 150 ? 18.377 -23.791 -12.752 1.00 18.84 ? 150 PHE B C 1 ATOM 4539 O O . PHE B 1 150 ? 17.633 -22.978 -13.280 1.00 18.27 ? 150 PHE B O 1 ATOM 4540 C CB . PHE B 1 150 ? 19.726 -23.346 -10.603 1.00 18.12 ? 150 PHE B CB 1 ATOM 4541 C CG . PHE B 1 150 ? 20.046 -21.910 -10.965 1.00 16.69 ? 150 PHE B CG 1 ATOM 4542 C CD1 . PHE B 1 150 ? 20.548 -21.584 -12.184 1.00 16.71 ? 150 PHE B CD1 1 ATOM 4543 C CD2 . PHE B 1 150 ? 19.968 -20.913 -10.005 1.00 17.07 ? 150 PHE B CD2 1 ATOM 4544 C CE1 . PHE B 1 150 ? 20.886 -20.226 -12.494 1.00 14.92 ? 150 PHE B CE1 1 ATOM 4545 C CE2 . PHE B 1 150 ? 20.303 -19.618 -10.269 1.00 14.89 ? 150 PHE B CE2 1 ATOM 4546 C CZ . PHE B 1 150 ? 20.773 -19.254 -11.509 1.00 13.89 ? 150 PHE B CZ 1 ATOM 4547 N N . ILE B 1 151 ? 19.149 -24.627 -13.460 1.00 19.42 ? 151 ILE B N 1 ATOM 4548 C CA . ILE B 1 151 ? 19.159 -24.571 -14.917 1.00 19.83 ? 151 ILE B CA 1 ATOM 4549 C C . ILE B 1 151 ? 17.770 -24.873 -15.480 1.00 21.49 ? 151 ILE B C 1 ATOM 4550 O O . ILE B 1 151 ? 17.282 -24.195 -16.394 1.00 21.18 ? 151 ILE B O 1 ATOM 4551 C CB . ILE B 1 151 ? 20.137 -25.515 -15.504 1.00 20.27 ? 151 ILE B CB 1 ATOM 4552 C CG1 . ILE B 1 151 ? 21.543 -24.945 -15.300 1.00 15.25 ? 151 ILE B CG1 1 ATOM 4553 C CG2 . ILE B 1 151 ? 19.719 -25.774 -16.986 1.00 19.05 ? 151 ILE B CG2 1 ATOM 4554 C CD1 . ILE B 1 151 ? 22.695 -25.928 -15.459 1.00 16.92 ? 151 ILE B CD1 1 ATOM 4555 N N . GLU B 1 152 ? 17.111 -25.865 -14.899 1.00 21.77 ? 152 GLU B N 1 ATOM 4556 C CA . GLU B 1 152 ? 15.732 -26.149 -15.267 1.00 22.31 ? 152 GLU B CA 1 ATOM 4557 C C . GLU B 1 152 ? 14.834 -24.925 -15.294 1.00 21.59 ? 152 GLU B C 1 ATOM 4558 O O . GLU B 1 152 ? 14.095 -24.735 -16.234 1.00 20.33 ? 152 GLU B O 1 ATOM 4559 C CB . GLU B 1 152 ? 15.127 -27.137 -14.295 1.00 22.55 ? 152 GLU B CB 1 ATOM 4560 C CG . GLU B 1 152 ? 14.289 -28.226 -14.960 1.00 26.50 ? 152 GLU B CG 1 ATOM 4561 C CD . GLU B 1 152 ? 13.693 -29.207 -13.964 1.00 28.98 ? 152 GLU B CD 1 ATOM 4562 O OE1 . GLU B 1 152 ? 14.467 -29.783 -13.168 1.00 31.34 ? 152 GLU B OE1 1 ATOM 4563 O OE2 . GLU B 1 152 ? 12.452 -29.406 -13.984 1.00 30.80 ? 152 GLU B OE2 1 ATOM 4564 N N . GLY B 1 153 ? 14.835 -24.128 -14.232 1.00 21.07 ? 153 GLY B N 1 ATOM 4565 C CA . GLY B 1 153 ? 13.870 -23.047 -14.143 1.00 20.10 ? 153 GLY B CA 1 ATOM 4566 C C . GLY B 1 153 ? 14.278 -21.896 -15.051 1.00 20.35 ? 153 GLY B C 1 ATOM 4567 O O . GLY B 1 153 ? 13.432 -21.190 -15.616 1.00 20.77 ? 153 GLY B O 1 ATOM 4568 N N . PHE B 1 154 ? 15.580 -21.685 -15.138 1.00 19.90 ? 154 PHE B N 1 ATOM 4569 C CA . PHE B 1 154 ? 16.173 -20.750 -16.071 1.00 21.31 ? 154 PHE B CA 1 ATOM 4570 C C . PHE B 1 154 ? 15.742 -21.071 -17.493 1.00 21.61 ? 154 PHE B C 1 ATOM 4571 O O . PHE B 1 154 ? 15.282 -20.200 -18.168 1.00 21.37 ? 154 PHE B O 1 ATOM 4572 C CB . PHE B 1 154 ? 17.684 -20.861 -15.992 1.00 19.66 ? 154 PHE B CB 1 ATOM 4573 C CG . PHE B 1 154 ? 18.443 -19.879 -16.841 1.00 21.00 ? 154 PHE B CG 1 ATOM 4574 C CD1 . PHE B 1 154 ? 18.781 -20.200 -18.180 1.00 20.76 ? 154 PHE B CD1 1 ATOM 4575 C CD2 . PHE B 1 154 ? 18.946 -18.668 -16.279 1.00 20.17 ? 154 PHE B CD2 1 ATOM 4576 C CE1 . PHE B 1 154 ? 19.554 -19.333 -18.946 1.00 20.04 ? 154 PHE B CE1 1 ATOM 4577 C CE2 . PHE B 1 154 ? 19.788 -17.759 -17.057 1.00 16.94 ? 154 PHE B CE2 1 ATOM 4578 C CZ . PHE B 1 154 ? 20.076 -18.085 -18.379 1.00 19.80 ? 154 PHE B CZ 1 ATOM 4579 N N . GLN B 1 155 ? 15.931 -22.317 -17.921 1.00 22.88 ? 155 GLN B N 1 ATOM 4580 C CA . GLN B 1 155 ? 15.567 -22.763 -19.277 1.00 23.77 ? 155 GLN B CA 1 ATOM 4581 C C . GLN B 1 155 ? 14.035 -22.649 -19.510 1.00 24.25 ? 155 GLN B C 1 ATOM 4582 O O . GLN B 1 155 ? 13.635 -22.081 -20.526 1.00 24.40 ? 155 GLN B O 1 ATOM 4583 C CB . GLN B 1 155 ? 16.147 -24.157 -19.594 1.00 23.50 ? 155 GLN B CB 1 ATOM 4584 N N . SER B 1 156 ? 13.194 -23.083 -18.550 1.00 23.93 ? 156 SER B N 1 ATOM 4585 C CA . SER B 1 156 ? 11.736 -22.880 -18.657 1.00 24.15 ? 156 SER B CA 1 ATOM 4586 C C . SER B 1 156 ? 11.395 -21.445 -18.955 1.00 24.13 ? 156 SER B C 1 ATOM 4587 O O . SER B 1 156 ? 10.474 -21.171 -19.727 1.00 25.95 ? 156 SER B O 1 ATOM 4588 C CB . SER B 1 156 ? 10.990 -23.234 -17.374 1.00 24.78 ? 156 SER B CB 1 ATOM 4589 O OG . SER B 1 156 ? 11.008 -24.621 -17.129 1.00 28.44 ? 156 SER B OG 1 ATOM 4590 N N . THR B 1 157 ? 12.107 -20.517 -18.335 1.00 22.95 ? 157 THR B N 1 ATOM 4591 C CA . THR B 1 157 ? 11.756 -19.105 -18.448 1.00 22.08 ? 157 THR B CA 1 ATOM 4592 C C . THR B 1 157 ? 12.248 -18.537 -19.772 1.00 21.75 ? 157 THR B C 1 ATOM 4593 O O . THR B 1 157 ? 11.482 -17.843 -20.454 1.00 21.44 ? 157 THR B O 1 ATOM 4594 C CB . THR B 1 157 ? 12.283 -18.271 -17.246 1.00 21.37 ? 157 THR B CB 1 ATOM 4595 O OG1 . THR B 1 157 ? 11.952 -18.985 -16.070 1.00 21.36 ? 157 THR B OG1 1 ATOM 4596 C CG2 . THR B 1 157 ? 11.631 -16.967 -17.170 1.00 20.26 ? 157 THR B CG2 1 ATOM 4597 N N . LYS B 1 158 ? 13.487 -18.850 -20.151 1.00 21.44 ? 158 LYS B N 1 ATOM 4598 C CA . LYS B 1 158 ? 13.977 -18.464 -21.475 1.00 21.73 ? 158 LYS B CA 1 ATOM 4599 C C . LYS B 1 158 ? 12.964 -18.907 -22.590 1.00 23.80 ? 158 LYS B C 1 ATOM 4600 O O . LYS B 1 158 ? 12.657 -18.109 -23.461 1.00 24.88 ? 158 LYS B O 1 ATOM 4601 C CB . LYS B 1 158 ? 15.363 -19.067 -21.726 1.00 21.48 ? 158 LYS B CB 1 ATOM 4602 C CG . LYS B 1 158 ? 16.136 -18.370 -22.794 1.00 17.48 ? 158 LYS B CG 1 ATOM 4603 C CD . LYS B 1 158 ? 17.365 -19.091 -23.188 1.00 14.16 ? 158 LYS B CD 1 ATOM 4604 C CE . LYS B 1 158 ? 18.248 -18.162 -24.057 1.00 13.94 ? 158 LYS B CE 1 ATOM 4605 N NZ . LYS B 1 158 ? 19.551 -18.851 -24.486 1.00 15.98 ? 158 LYS B NZ 1 ATOM 4606 N N . LEU B 1 159 ? 12.425 -20.134 -22.528 1.00 24.58 ? 159 LEU B N 1 ATOM 4607 C CA . LEU B 1 159 ? 11.455 -20.643 -23.519 1.00 26.38 ? 159 LEU B CA 1 ATOM 4608 C C . LEU B 1 159 ? 10.187 -19.814 -23.636 1.00 26.93 ? 159 LEU B C 1 ATOM 4609 O O . LEU B 1 159 ? 9.581 -19.757 -24.709 1.00 26.17 ? 159 LEU B O 1 ATOM 4610 C CB . LEU B 1 159 ? 11.012 -22.075 -23.197 1.00 27.35 ? 159 LEU B CB 1 ATOM 4611 C CG . LEU B 1 159 ? 11.749 -23.310 -23.762 1.00 31.75 ? 159 LEU B CG 1 ATOM 4612 C CD1 . LEU B 1 159 ? 11.047 -24.657 -23.277 1.00 32.69 ? 159 LEU B CD1 1 ATOM 4613 C CD2 . LEU B 1 159 ? 11.959 -23.282 -25.328 1.00 30.93 ? 159 LEU B CD2 1 ATOM 4614 N N . LYS B 1 160 ? 9.769 -19.202 -22.538 1.00 27.16 ? 160 LYS B N 1 ATOM 4615 C CA . LYS B 1 160 ? 8.572 -18.395 -22.566 1.00 28.84 ? 160 LYS B CA 1 ATOM 4616 C C . LYS B 1 160 ? 8.848 -16.931 -22.885 1.00 28.33 ? 160 LYS B C 1 ATOM 4617 O O . LYS B 1 160 ? 7.940 -16.108 -22.897 1.00 30.00 ? 160 LYS B O 1 ATOM 4618 C CB . LYS B 1 160 ? 7.765 -18.557 -21.269 1.00 28.87 ? 160 LYS B CB 1 ATOM 4619 C CG . LYS B 1 160 ? 7.290 -19.991 -21.112 1.00 34.03 ? 160 LYS B CG 1 ATOM 4620 C CD . LYS B 1 160 ? 6.092 -20.181 -20.171 1.00 42.73 ? 160 LYS B CD 1 ATOM 4621 C CE . LYS B 1 160 ? 6.513 -20.822 -18.825 1.00 45.84 ? 160 LYS B CE 1 ATOM 4622 N NZ . LYS B 1 160 ? 7.225 -19.811 -17.960 1.00 43.73 ? 160 LYS B NZ 1 ATOM 4623 N N . ASP B 1 161 ? 10.097 -16.596 -23.154 1.00 27.99 ? 161 ASP B N 1 ATOM 4624 C CA . ASP B 1 161 ? 10.441 -15.209 -23.279 1.00 27.67 ? 161 ASP B CA 1 ATOM 4625 C C . ASP B 1 161 ? 10.415 -14.885 -24.769 1.00 27.63 ? 161 ASP B C 1 ATOM 4626 O O . ASP B 1 161 ? 11.200 -15.455 -25.528 1.00 27.14 ? 161 ASP B O 1 ATOM 4627 C CB . ASP B 1 161 ? 11.829 -14.984 -22.696 1.00 27.57 ? 161 ASP B CB 1 ATOM 4628 C CG . ASP B 1 161 ? 12.338 -13.543 -22.865 1.00 26.66 ? 161 ASP B CG 1 ATOM 4629 O OD1 . ASP B 1 161 ? 11.584 -12.626 -23.291 1.00 29.82 ? 161 ASP B OD1 1 ATOM 4630 O OD2 . ASP B 1 161 ? 13.516 -13.317 -22.527 1.00 24.90 ? 161 ASP B OD2 1 ATOM 4631 N N . PRO B 1 162 ? 9.547 -13.937 -25.174 1.00 27.67 ? 162 PRO B N 1 ATOM 4632 C CA . PRO B 1 162 ? 9.387 -13.573 -26.589 1.00 27.33 ? 162 PRO B CA 1 ATOM 4633 C C . PRO B 1 162 ? 10.658 -12.931 -27.172 1.00 27.94 ? 162 PRO B C 1 ATOM 4634 O O . PRO B 1 162 ? 10.903 -12.990 -28.382 1.00 27.33 ? 162 PRO B O 1 ATOM 4635 C CB . PRO B 1 162 ? 8.200 -12.594 -26.563 1.00 27.57 ? 162 PRO B CB 1 ATOM 4636 C CG . PRO B 1 162 ? 8.242 -11.981 -25.201 1.00 27.47 ? 162 PRO B CG 1 ATOM 4637 C CD . PRO B 1 162 ? 8.667 -13.136 -24.292 1.00 27.28 ? 162 PRO B CD 1 ATOM 4638 N N . ARG B 1 163 ? 11.487 -12.368 -26.294 1.00 28.81 ? 163 ARG B N 1 ATOM 4639 C CA . ARG B 1 163 ? 12.737 -11.718 -26.665 1.00 28.26 ? 163 ARG B CA 1 ATOM 4640 C C . ARG B 1 163 ? 13.941 -12.638 -26.696 1.00 28.49 ? 163 ARG B C 1 ATOM 4641 O O . ARG B 1 163 ? 15.009 -12.239 -27.147 1.00 28.94 ? 163 ARG B O 1 ATOM 4642 C CB . ARG B 1 163 ? 12.964 -10.515 -25.749 1.00 28.02 ? 163 ARG B CB 1 ATOM 4643 C CG . ARG B 1 163 ? 11.955 -9.428 -26.004 1.00 28.41 ? 163 ARG B CG 1 ATOM 4644 C CD . ARG B 1 163 ? 11.900 -8.311 -24.975 1.00 28.33 ? 163 ARG B CD 1 ATOM 4645 N NE . ARG B 1 163 ? 10.625 -8.455 -24.276 1.00 34.93 ? 163 ARG B NE 1 ATOM 4646 C CZ . ARG B 1 163 ? 9.536 -7.756 -24.552 1.00 33.51 ? 163 ARG B CZ 1 ATOM 4647 N NH1 . ARG B 1 163 ? 9.575 -6.833 -25.476 1.00 36.55 ? 163 ARG B NH1 1 ATOM 4648 N NH2 . ARG B 1 163 ? 8.421 -7.947 -23.884 1.00 34.93 ? 163 ARG B NH2 1 ATOM 4649 N N . ALA B 1 164 ? 13.785 -13.869 -26.245 1.00 29.20 ? 164 ALA B N 1 ATOM 4650 C CA . ALA B 1 164 ? 14.901 -14.784 -26.150 1.00 30.44 ? 164 ALA B CA 1 ATOM 4651 C C . ALA B 1 164 ? 15.337 -15.246 -27.524 1.00 31.77 ? 164 ALA B C 1 ATOM 4652 O O . ALA B 1 164 ? 14.490 -15.572 -28.333 1.00 33.86 ? 164 ALA B O 1 ATOM 4653 C CB . ALA B 1 164 ? 14.501 -15.971 -25.328 1.00 30.07 ? 164 ALA B CB 1 ATOM 4654 N N . GLN B 1 165 ? 16.641 -15.317 -27.787 1.00 32.15 ? 165 GLN B N 1 ATOM 4655 C CA . GLN B 1 165 ? 17.115 -15.920 -29.007 1.00 32.12 ? 165 GLN B CA 1 ATOM 4656 C C . GLN B 1 165 ? 17.088 -17.464 -28.887 1.00 33.36 ? 165 GLN B C 1 ATOM 4657 O O . GLN B 1 165 ? 17.943 -18.056 -28.203 1.00 33.95 ? 165 GLN B O 1 ATOM 4658 C CB . GLN B 1 165 ? 18.506 -15.391 -29.328 1.00 32.32 ? 165 GLN B CB 1 ATOM 4659 C CG . GLN B 1 165 ? 19.213 -16.102 -30.483 1.00 33.03 ? 165 GLN B CG 1 ATOM 4660 C CD . GLN B 1 165 ? 20.467 -15.379 -30.888 1.00 34.74 ? 165 GLN B CD 1 ATOM 4661 O OE1 . GLN B 1 165 ? 20.744 -14.307 -30.392 1.00 36.67 ? 165 GLN B OE1 1 ATOM 4662 N NE2 . GLN B 1 165 ? 21.245 -15.968 -31.783 1.00 36.50 ? 165 GLN B NE2 1 ATOM 4663 N N . PRO B 1 166 ? 16.113 -18.132 -29.550 1.00 33.77 ? 166 PRO B N 1 ATOM 4664 C CA . PRO B 1 166 ? 15.842 -19.602 -29.490 1.00 33.21 ? 166 PRO B CA 1 ATOM 4665 C C . PRO B 1 166 ? 16.862 -20.503 -30.172 1.00 33.52 ? 166 PRO B C 1 ATOM 4666 O O . PRO B 1 166 ? 17.731 -20.016 -30.925 1.00 32.11 ? 166 PRO B O 1 ATOM 4667 C CB . PRO B 1 166 ? 14.521 -19.747 -30.223 1.00 34.37 ? 166 PRO B CB 1 ATOM 4668 C CG . PRO B 1 166 ? 14.566 -18.619 -31.248 1.00 34.63 ? 166 PRO B CG 1 ATOM 4669 C CD . PRO B 1 166 ? 15.266 -17.455 -30.550 1.00 33.64 ? 166 PRO B CD 1 ATOM 4670 N N . GLY B 1 167 ? 16.773 -21.814 -29.860 1.00 34.06 ? 167 GLY B N 1 ATOM 4671 C CA . GLY B 1 167 ? 17.773 -22.832 -30.275 1.00 33.58 ? 167 GLY B CA 1 ATOM 4672 C C . GLY B 1 167 ? 19.251 -22.497 -30.006 1.00 34.08 ? 167 GLY B C 1 ATOM 4673 O O . GLY B 1 167 ? 20.149 -22.730 -30.864 1.00 34.08 ? 167 GLY B O 1 ATOM 4674 N N . GLN B 1 168 ? 19.522 -21.910 -28.835 1.00 32.78 ? 168 GLN B N 1 ATOM 4675 C CA . GLN B 1 168 ? 20.913 -21.745 -28.391 1.00 31.31 ? 168 GLN B CA 1 ATOM 4676 C C . GLN B 1 168 ? 21.346 -23.042 -27.694 1.00 30.09 ? 168 GLN B C 1 ATOM 4677 O O . GLN B 1 168 ? 20.478 -23.851 -27.329 1.00 28.15 ? 168 GLN B O 1 ATOM 4678 C CB . GLN B 1 168 ? 20.994 -20.549 -27.474 1.00 31.08 ? 168 GLN B CB 1 ATOM 4679 C CG . GLN B 1 168 ? 20.929 -19.265 -28.279 1.00 31.46 ? 168 GLN B CG 1 ATOM 4680 C CD . GLN B 1 168 ? 21.492 -18.098 -27.515 1.00 31.84 ? 168 GLN B CD 1 ATOM 4681 O OE1 . GLN B 1 168 ? 20.886 -17.639 -26.536 1.00 28.32 ? 168 GLN B OE1 1 ATOM 4682 N NE2 . GLN B 1 168 ? 22.660 -17.602 -27.954 1.00 29.74 ? 168 GLN B NE2 1 ATOM 4683 N N . SER B 1 169 ? 22.646 -23.275 -27.490 1.00 29.60 ? 169 SER B N 1 ATOM 4684 C CA . SER B 1 169 ? 22.967 -24.488 -26.702 1.00 29.47 ? 169 SER B CA 1 ATOM 4685 C C . SER B 1 169 ? 22.318 -24.372 -25.321 1.00 28.27 ? 169 SER B C 1 ATOM 4686 O O . SER B 1 169 ? 22.006 -23.279 -24.852 1.00 27.25 ? 169 SER B O 1 ATOM 4687 C CB . SER B 1 169 ? 24.462 -24.824 -26.634 1.00 29.22 ? 169 SER B CB 1 ATOM 4688 O OG . SER B 1 169 ? 25.233 -23.665 -26.487 1.00 33.30 ? 169 SER B OG 1 ATOM 4689 N N . SER B 1 170 ? 22.048 -25.505 -24.703 1.00 28.39 ? 170 SER B N 1 ATOM 4690 C CA . SER B 1 170 ? 21.502 -25.507 -23.340 1.00 28.60 ? 170 SER B CA 1 ATOM 4691 C C . SER B 1 170 ? 22.518 -24.927 -22.338 1.00 26.78 ? 170 SER B C 1 ATOM 4692 O O . SER B 1 170 ? 23.724 -25.123 -22.506 1.00 25.62 ? 170 SER B O 1 ATOM 4693 C CB . SER B 1 170 ? 21.139 -26.950 -22.916 1.00 30.21 ? 170 SER B CB 1 ATOM 4694 O OG . SER B 1 170 ? 20.130 -27.503 -23.767 1.00 34.46 ? 170 SER B OG 1 ATOM 4695 N N . PRO B 1 171 ? 22.034 -24.218 -21.296 1.00 25.55 ? 171 PRO B N 1 ATOM 4696 C CA . PRO B 1 171 ? 22.948 -24.056 -20.150 1.00 25.28 ? 171 PRO B CA 1 ATOM 4697 C C . PRO B 1 171 ? 23.145 -25.435 -19.500 1.00 24.59 ? 171 PRO B C 1 ATOM 4698 O O . PRO B 1 171 ? 22.189 -26.221 -19.452 1.00 24.96 ? 171 PRO B O 1 ATOM 4699 C CB . PRO B 1 171 ? 22.184 -23.126 -19.196 1.00 25.34 ? 171 PRO B CB 1 ATOM 4700 C CG . PRO B 1 171 ? 20.886 -22.796 -19.855 1.00 25.52 ? 171 PRO B CG 1 ATOM 4701 C CD . PRO B 1 171 ? 20.695 -23.674 -21.049 1.00 25.11 ? 171 PRO B CD 1 ATOM 4702 N N . LYS B 1 172 ? 24.355 -25.733 -19.038 1.00 22.39 ? 172 LYS B N 1 ATOM 4703 C CA . LYS B 1 172 ? 24.599 -26.968 -18.324 1.00 22.48 ? 172 LYS B CA 1 ATOM 4704 C C . LYS B 1 172 ? 25.723 -26.708 -17.315 1.00 22.53 ? 172 LYS B C 1 ATOM 4705 O O . LYS B 1 172 ? 26.353 -25.642 -17.337 1.00 22.84 ? 172 LYS B O 1 ATOM 4706 C CB . LYS B 1 172 ? 25.052 -28.048 -19.319 1.00 22.11 ? 172 LYS B CB 1 ATOM 4707 C CG . LYS B 1 172 ? 26.309 -27.548 -20.056 1.00 22.75 ? 172 LYS B CG 1 ATOM 4708 C CD . LYS B 1 172 ? 26.893 -28.472 -21.050 1.00 23.70 ? 172 LYS B CD 1 ATOM 4709 C CE . LYS B 1 172 ? 27.795 -27.667 -21.998 1.00 26.44 ? 172 LYS B CE 1 ATOM 4710 N NZ . LYS B 1 172 ? 28.852 -28.649 -22.402 1.00 28.86 ? 172 LYS B NZ 1 ATOM 4711 N N . ILE B 1 173 ? 25.994 -27.705 -16.466 1.00 21.66 ? 173 ILE B N 1 ATOM 4712 C CA . ILE B 1 173 ? 27.085 -27.643 -15.574 1.00 20.88 ? 173 ILE B CA 1 ATOM 4713 C C . ILE B 1 173 ? 28.361 -27.930 -16.357 1.00 22.18 ? 173 ILE B C 1 ATOM 4714 O O . ILE B 1 173 ? 28.705 -29.071 -16.711 1.00 23.11 ? 173 ILE B O 1 ATOM 4715 C CB . ILE B 1 173 ? 26.903 -28.572 -14.334 1.00 20.56 ? 173 ILE B CB 1 ATOM 4716 C CG1 . ILE B 1 173 ? 25.684 -28.167 -13.536 1.00 17.49 ? 173 ILE B CG1 1 ATOM 4717 C CG2 . ILE B 1 173 ? 28.106 -28.457 -13.420 1.00 19.95 ? 173 ILE B CG2 1 ATOM 4718 C CD1 . ILE B 1 173 ? 25.424 -29.183 -12.373 1.00 21.51 ? 173 ILE B CD1 1 ATOM 4719 N N . ASP B 1 174 ? 29.060 -26.870 -16.665 1.00 22.38 ? 174 ASP B N 1 ATOM 4720 C CA . ASP B 1 174 ? 30.273 -27.022 -17.455 1.00 23.39 ? 174 ASP B CA 1 ATOM 4721 C C . ASP B 1 174 ? 31.403 -27.726 -16.750 1.00 23.97 ? 174 ASP B C 1 ATOM 4722 O O . ASP B 1 174 ? 32.204 -28.390 -17.387 1.00 24.81 ? 174 ASP B O 1 ATOM 4723 C CB . ASP B 1 174 ? 30.737 -25.624 -17.922 1.00 23.19 ? 174 ASP B CB 1 ATOM 4724 C CG . ASP B 1 174 ? 29.720 -24.962 -18.855 1.00 25.32 ? 174 ASP B CG 1 ATOM 4725 O OD1 . ASP B 1 174 ? 29.815 -25.254 -20.068 1.00 27.48 ? 174 ASP B OD1 1 ATOM 4726 O OD2 . ASP B 1 174 ? 28.828 -24.196 -18.398 1.00 21.44 ? 174 ASP B OD2 1 ATOM 4727 N N . VAL B 1 175 ? 31.547 -27.467 -15.444 1.00 25.40 ? 175 VAL B N 1 ATOM 4728 C CA . VAL B 1 175 ? 32.655 -28.006 -14.630 1.00 24.68 ? 175 VAL B CA 1 ATOM 4729 C C . VAL B 1 175 ? 32.091 -28.418 -13.263 1.00 24.91 ? 175 VAL B C 1 ATOM 4730 O O . VAL B 1 175 ? 31.474 -27.598 -12.534 1.00 24.45 ? 175 VAL B O 1 ATOM 4731 C CB . VAL B 1 175 ? 33.747 -26.965 -14.375 1.00 25.03 ? 175 VAL B CB 1 ATOM 4732 C CG1 . VAL B 1 175 ? 34.912 -27.608 -13.627 1.00 24.10 ? 175 VAL B CG1 1 ATOM 4733 C CG2 . VAL B 1 175 ? 34.211 -26.294 -15.658 1.00 25.18 ? 175 VAL B CG2 1 ATOM 4734 N N . VAL B 1 176 ? 32.279 -29.691 -12.945 1.00 25.32 ? 176 VAL B N 1 ATOM 4735 C CA . VAL B 1 176 ? 32.010 -30.239 -11.607 1.00 25.21 ? 176 VAL B CA 1 ATOM 4736 C C . VAL B 1 176 ? 33.378 -30.267 -10.964 1.00 24.71 ? 176 VAL B C 1 ATOM 4737 O O . VAL B 1 176 ? 34.255 -30.982 -11.449 1.00 24.58 ? 176 VAL B O 1 ATOM 4738 C CB . VAL B 1 176 ? 31.457 -31.662 -11.692 1.00 25.66 ? 176 VAL B CB 1 ATOM 4739 C CG1 . VAL B 1 176 ? 31.158 -32.192 -10.276 1.00 29.12 ? 176 VAL B CG1 1 ATOM 4740 C CG2 . VAL B 1 176 ? 30.196 -31.680 -12.501 1.00 25.17 ? 176 VAL B CG2 1 ATOM 4741 N N . ILE B 1 177 ? 33.580 -29.422 -9.939 1.00 23.23 ? 177 ILE B N 1 ATOM 4742 C CA . ILE B 1 177 ? 34.851 -29.372 -9.230 1.00 21.75 ? 177 ILE B CA 1 ATOM 4743 C C . ILE B 1 177 ? 34.869 -30.444 -8.118 1.00 21.69 ? 177 ILE B C 1 ATOM 4744 O O . ILE B 1 177 ? 33.948 -30.525 -7.328 1.00 21.01 ? 177 ILE B O 1 ATOM 4745 C CB . ILE B 1 177 ? 35.098 -28.004 -8.592 1.00 20.40 ? 177 ILE B CB 1 ATOM 4746 C CG1 . ILE B 1 177 ? 34.990 -26.884 -9.632 1.00 17.96 ? 177 ILE B CG1 1 ATOM 4747 C CG2 . ILE B 1 177 ? 36.440 -27.998 -7.972 1.00 22.36 ? 177 ILE B CG2 1 ATOM 4748 C CD1 . ILE B 1 177 ? 35.449 -25.547 -9.158 1.00 15.65 ? 177 ILE B CD1 1 ATOM 4749 N N . SER B 1 178 ? 35.926 -31.241 -8.062 1.00 22.64 ? 178 SER B N 1 ATOM 4750 C CA . SER B 1 178 ? 36.031 -32.308 -7.045 1.00 23.83 ? 178 SER B CA 1 ATOM 4751 C C . SER B 1 178 ? 36.172 -31.840 -5.580 1.00 24.27 ? 178 SER B C 1 ATOM 4752 O O . SER B 1 178 ? 37.041 -31.019 -5.271 1.00 23.23 ? 178 SER B O 1 ATOM 4753 C CB . SER B 1 178 ? 37.236 -33.217 -7.353 1.00 22.94 ? 178 SER B CB 1 ATOM 4754 O OG . SER B 1 178 ? 37.306 -34.238 -6.363 1.00 23.25 ? 178 SER B OG 1 ATOM 4755 N N . GLU B 1 179 ? 35.370 -32.441 -4.706 1.00 24.65 ? 179 GLU B N 1 ATOM 4756 C CA . GLU B 1 179 ? 35.520 -32.324 -3.263 1.00 26.44 ? 179 GLU B CA 1 ATOM 4757 C C . GLU B 1 179 ? 36.534 -33.304 -2.600 1.00 27.48 ? 179 GLU B C 1 ATOM 4758 O O . GLU B 1 179 ? 36.695 -33.278 -1.370 1.00 27.44 ? 179 GLU B O 1 ATOM 4759 C CB . GLU B 1 179 ? 34.161 -32.518 -2.593 1.00 26.38 ? 179 GLU B CB 1 ATOM 4760 C CG . GLU B 1 179 ? 33.174 -31.479 -3.010 1.00 27.66 ? 179 GLU B CG 1 ATOM 4761 C CD . GLU B 1 179 ? 31.918 -31.468 -2.180 1.00 29.57 ? 179 GLU B CD 1 ATOM 4762 O OE1 . GLU B 1 179 ? 31.753 -32.299 -1.250 1.00 31.20 ? 179 GLU B OE1 1 ATOM 4763 O OE2 . GLU B 1 179 ? 31.071 -30.602 -2.480 1.00 33.02 ? 179 GLU B OE2 1 ATOM 4764 N N . ALA B 1 180 ? 37.193 -34.180 -3.380 1.00 28.34 ? 180 ALA B N 1 ATOM 4765 C CA . ALA B 1 180 ? 38.184 -35.081 -2.784 1.00 28.28 ? 180 ALA B CA 1 ATOM 4766 C C . ALA B 1 180 ? 39.199 -34.205 -2.046 1.00 29.23 ? 180 ALA B C 1 ATOM 4767 O O . ALA B 1 180 ? 39.300 -32.980 -2.296 1.00 27.90 ? 180 ALA B O 1 ATOM 4768 C CB . ALA B 1 180 ? 38.860 -35.926 -3.812 1.00 27.45 ? 180 ALA B CB 1 ATOM 4769 N N . SER B 1 181 ? 39.954 -34.846 -1.159 1.00 29.42 ? 181 SER B N 1 ATOM 4770 C CA . SER B 1 181 ? 40.818 -34.157 -0.200 1.00 30.31 ? 181 SER B CA 1 ATOM 4771 C C . SER B 1 181 ? 42.023 -33.549 -0.881 1.00 30.00 ? 181 SER B C 1 ATOM 4772 O O . SER B 1 181 ? 42.576 -32.569 -0.383 1.00 30.96 ? 181 SER B O 1 ATOM 4773 C CB . SER B 1 181 ? 41.259 -35.128 0.932 1.00 31.10 ? 181 SER B CB 1 ATOM 4774 O OG . SER B 1 181 ? 41.713 -36.375 0.369 1.00 31.50 ? 181 SER B OG 1 ATOM 4775 N N . SER B 1 182 ? 42.446 -34.124 -2.003 1.00 29.43 ? 182 SER B N 1 ATOM 4776 C CA . SER B 1 182 ? 43.564 -33.573 -2.783 1.00 29.17 ? 182 SER B CA 1 ATOM 4777 C C . SER B 1 182 ? 43.144 -32.456 -3.773 1.00 28.36 ? 182 SER B C 1 ATOM 4778 O O . SER B 1 182 ? 44.000 -31.740 -4.325 1.00 28.70 ? 182 SER B O 1 ATOM 4779 C CB . SER B 1 182 ? 44.170 -34.693 -3.614 1.00 30.58 ? 182 SER B CB 1 ATOM 4780 O OG . SER B 1 182 ? 43.151 -35.404 -4.329 1.00 32.15 ? 182 SER B OG 1 ATOM 4781 N N . SER B 1 183 ? 41.842 -32.333 -4.019 1.00 26.42 ? 183 SER B N 1 ATOM 4782 C CA . SER B 1 183 ? 41.289 -31.343 -4.949 1.00 25.09 ? 183 SER B CA 1 ATOM 4783 C C . SER B 1 183 ? 41.395 -29.834 -4.550 1.00 23.86 ? 183 SER B C 1 ATOM 4784 O O . SER B 1 183 ? 40.933 -29.435 -3.479 1.00 22.78 ? 183 SER B O 1 ATOM 4785 C CB . SER B 1 183 ? 39.836 -31.703 -5.168 1.00 25.19 ? 183 SER B CB 1 ATOM 4786 O OG . SER B 1 183 ? 39.252 -30.895 -6.175 1.00 27.87 ? 183 SER B OG 1 ATOM 4787 N N . ASN B 1 184 ? 42.022 -29.012 -5.399 1.00 22.25 ? 184 ASN B N 1 ATOM 4788 C CA . ASN B 1 184 ? 41.925 -27.571 -5.283 1.00 21.61 ? 184 ASN B CA 1 ATOM 4789 C C . ASN B 1 184 ? 40.513 -27.136 -5.714 1.00 21.02 ? 184 ASN B C 1 ATOM 4790 O O . ASN B 1 184 ? 40.220 -27.144 -6.886 1.00 20.46 ? 184 ASN B O 1 ATOM 4791 C CB . ASN B 1 184 ? 43.020 -26.845 -6.097 1.00 22.13 ? 184 ASN B CB 1 ATOM 4792 C CG . ASN B 1 184 ? 44.428 -27.104 -5.548 1.00 24.09 ? 184 ASN B CG 1 ATOM 4793 O OD1 . ASN B 1 184 ? 44.573 -27.754 -4.520 1.00 26.74 ? 184 ASN B OD1 1 ATOM 4794 N ND2 . ASN B 1 184 ? 45.453 -26.602 -6.209 1.00 27.89 ? 184 ASN B ND2 1 ATOM 4795 N N . ASN B 1 185 ? 39.646 -26.773 -4.751 1.00 19.80 ? 185 ASN B N 1 ATOM 4796 C CA . ASN B 1 185 ? 38.234 -26.409 -4.987 1.00 18.08 ? 185 ASN B CA 1 ATOM 4797 C C . ASN B 1 185 ? 37.951 -24.987 -4.430 1.00 18.92 ? 185 ASN B C 1 ATOM 4798 O O . ASN B 1 185 ? 37.806 -24.844 -3.222 1.00 18.97 ? 185 ASN B O 1 ATOM 4799 C CB . ASN B 1 185 ? 37.387 -27.429 -4.268 1.00 17.20 ? 185 ASN B CB 1 ATOM 4800 C CG . ASN B 1 185 ? 35.877 -27.285 -4.533 1.00 18.89 ? 185 ASN B CG 1 ATOM 4801 O OD1 . ASN B 1 185 ? 35.092 -28.248 -4.394 1.00 21.77 ? 185 ASN B OD1 1 ATOM 4802 N ND2 . ASN B 1 185 ? 35.465 -26.123 -4.911 1.00 14.19 ? 185 ASN B ND2 1 ATOM 4803 N N . THR B 1 186 ? 37.842 -23.952 -5.284 1.00 17.93 ? 186 THR B N 1 ATOM 4804 C CA . THR B 1 186 ? 37.712 -22.611 -4.803 1.00 17.18 ? 186 THR B CA 1 ATOM 4805 C C . THR B 1 186 ? 36.343 -22.444 -4.158 1.00 19.29 ? 186 THR B C 1 ATOM 4806 O O . THR B 1 186 ? 36.119 -21.473 -3.383 1.00 18.46 ? 186 THR B O 1 ATOM 4807 C CB . THR B 1 186 ? 37.878 -21.560 -5.912 1.00 17.21 ? 186 THR B CB 1 ATOM 4808 O OG1 . THR B 1 186 ? 36.932 -21.837 -6.943 1.00 16.27 ? 186 THR B OG1 1 ATOM 4809 C CG2 . THR B 1 186 ? 39.281 -21.610 -6.532 1.00 13.77 ? 186 THR B CG2 1 ATOM 4810 N N . LEU B 1 187 ? 35.447 -23.388 -4.450 1.00 18.99 ? 187 LEU B N 1 ATOM 4811 C CA . LEU B 1 187 ? 34.046 -23.285 -3.999 1.00 20.85 ? 187 LEU B CA 1 ATOM 4812 C C . LEU B 1 187 ? 33.893 -23.724 -2.578 1.00 21.71 ? 187 LEU B C 1 ATOM 4813 O O . LEU B 1 187 ? 32.980 -23.239 -1.880 1.00 21.64 ? 187 LEU B O 1 ATOM 4814 C CB . LEU B 1 187 ? 33.072 -24.119 -4.856 1.00 20.27 ? 187 LEU B CB 1 ATOM 4815 C CG . LEU B 1 187 ? 33.006 -23.829 -6.358 1.00 22.14 ? 187 LEU B CG 1 ATOM 4816 C CD1 . LEU B 1 187 ? 31.908 -24.701 -7.022 1.00 21.50 ? 187 LEU B CD1 1 ATOM 4817 C CD2 . LEU B 1 187 ? 32.707 -22.356 -6.576 1.00 20.29 ? 187 LEU B CD2 1 ATOM 4818 N N . ASP B 1 188 ? 34.767 -24.651 -2.163 1.00 21.58 ? 188 ASP B N 1 ATOM 4819 C CA . ASP B 1 188 ? 34.705 -25.212 -0.815 1.00 23.12 ? 188 ASP B CA 1 ATOM 4820 C C . ASP B 1 188 ? 36.018 -25.908 -0.571 1.00 21.11 ? 188 ASP B C 1 ATOM 4821 O O . ASP B 1 188 ? 36.098 -27.107 -0.811 1.00 20.13 ? 188 ASP B O 1 ATOM 4822 C CB . ASP B 1 188 ? 33.548 -26.200 -0.665 1.00 24.92 ? 188 ASP B CB 1 ATOM 4823 C CG . ASP B 1 188 ? 33.252 -26.555 0.817 1.00 32.47 ? 188 ASP B CG 1 ATOM 4824 O OD1 . ASP B 1 188 ? 32.860 -25.647 1.620 1.00 36.57 ? 188 ASP B OD1 1 ATOM 4825 O OD2 . ASP B 1 188 ? 33.398 -27.774 1.164 1.00 38.49 ? 188 ASP B OD2 1 ATOM 4826 N N . PRO B 1 189 ? 37.068 -25.137 -0.146 1.00 19.86 ? 189 PRO B N 1 ATOM 4827 C CA . PRO B 1 189 ? 38.415 -25.692 -0.081 1.00 19.93 ? 189 PRO B CA 1 ATOM 4828 C C . PRO B 1 189 ? 38.573 -26.717 1.028 1.00 20.09 ? 189 PRO B C 1 ATOM 4829 O O . PRO B 1 189 ? 37.963 -26.587 2.077 1.00 19.79 ? 189 PRO B O 1 ATOM 4830 C CB . PRO B 1 189 ? 39.300 -24.464 0.115 1.00 19.61 ? 189 PRO B CB 1 ATOM 4831 C CG . PRO B 1 189 ? 38.429 -23.305 -0.383 1.00 19.01 ? 189 PRO B CG 1 ATOM 4832 C CD . PRO B 1 189 ? 37.087 -23.676 0.077 1.00 19.69 ? 189 PRO B CD 1 ATOM 4833 N N . GLY B 1 190 ? 39.297 -27.792 0.757 1.00 21.43 ? 190 GLY B N 1 ATOM 4834 C CA . GLY B 1 190 ? 39.499 -28.826 1.787 1.00 22.86 ? 190 GLY B CA 1 ATOM 4835 C C . GLY B 1 190 ? 40.977 -29.125 1.985 1.00 23.42 ? 190 GLY B C 1 ATOM 4836 O O . GLY B 1 190 ? 41.325 -30.159 2.579 1.00 25.09 ? 190 GLY B O 1 ATOM 4837 N N . THR B 1 191 ? 41.840 -28.268 1.465 1.00 23.35 ? 191 THR B N 1 ATOM 4838 C CA . THR B 1 191 ? 43.269 -28.538 1.480 1.00 24.64 ? 191 THR B CA 1 ATOM 4839 C C . THR B 1 191 ? 44.121 -27.716 2.475 1.00 24.29 ? 191 THR B C 1 ATOM 4840 O O . THR B 1 191 ? 45.321 -27.921 2.549 1.00 24.73 ? 191 THR B O 1 ATOM 4841 C CB . THR B 1 191 ? 43.923 -28.373 0.052 1.00 25.42 ? 191 THR B CB 1 ATOM 4842 O OG1 . THR B 1 191 ? 43.511 -27.135 -0.542 1.00 27.08 ? 191 THR B OG1 1 ATOM 4843 C CG2 . THR B 1 191 ? 43.592 -29.527 -0.865 1.00 25.05 ? 191 THR B CG2 1 ATOM 4844 N N . CYS B 1 192 ? 43.527 -26.761 3.178 1.00 24.74 ? 192 CYS B N 1 ATOM 4845 C CA . CYS B 1 192 ? 44.245 -25.952 4.186 1.00 25.45 ? 192 CYS B CA 1 ATOM 4846 C C . CYS B 1 192 ? 44.349 -26.753 5.494 1.00 25.93 ? 192 CYS B C 1 ATOM 4847 O O . CYS B 1 192 ? 43.465 -26.700 6.342 1.00 25.32 ? 192 CYS B O 1 ATOM 4848 C CB . CYS B 1 192 ? 43.494 -24.647 4.436 1.00 24.67 ? 192 CYS B CB 1 ATOM 4849 S SG . CYS B 1 192 ? 44.272 -23.415 5.450 1.00 24.84 ? 192 CYS B SG 1 ATOM 4850 N N . THR B 1 193 ? 45.440 -27.497 5.650 1.00 27.42 ? 193 THR B N 1 ATOM 4851 C CA . THR B 1 193 ? 45.536 -28.501 6.730 1.00 27.99 ? 193 THR B CA 1 ATOM 4852 C C . THR B 1 193 ? 45.272 -27.900 8.146 1.00 27.15 ? 193 THR B C 1 ATOM 4853 O O . THR B 1 193 ? 44.484 -28.435 8.934 1.00 25.87 ? 193 THR B O 1 ATOM 4854 C CB . THR B 1 193 ? 46.887 -29.184 6.669 1.00 28.79 ? 193 THR B CB 1 ATOM 4855 O OG1 . THR B 1 193 ? 47.184 -29.494 5.303 1.00 30.30 ? 193 THR B OG1 1 ATOM 4856 C CG2 . THR B 1 193 ? 46.872 -30.494 7.480 1.00 31.43 ? 193 THR B CG2 1 ATOM 4857 N N . VAL B 1 194 ? 45.907 -26.766 8.438 1.00 26.52 ? 194 VAL B N 1 ATOM 4858 C CA . VAL B 1 194 ? 45.726 -26.165 9.719 1.00 26.19 ? 194 VAL B CA 1 ATOM 4859 C C . VAL B 1 194 ? 44.265 -25.756 9.923 1.00 26.80 ? 194 VAL B C 1 ATOM 4860 O O . VAL B 1 194 ? 43.706 -26.046 10.987 1.00 26.54 ? 194 VAL B O 1 ATOM 4861 C CB . VAL B 1 194 ? 46.687 -25.024 9.943 1.00 27.18 ? 194 VAL B CB 1 ATOM 4862 C CG1 . VAL B 1 194 ? 46.257 -24.145 11.218 1.00 27.03 ? 194 VAL B CG1 1 ATOM 4863 C CG2 . VAL B 1 194 ? 48.137 -25.550 10.066 1.00 26.11 ? 194 VAL B CG2 1 ATOM 4864 N N . PHE B 1 195 ? 43.626 -25.141 8.913 1.00 26.27 ? 195 PHE B N 1 ATOM 4865 C CA . PHE B 1 195 ? 42.239 -24.690 9.068 1.00 26.23 ? 195 PHE B CA 1 ATOM 4866 C C . PHE B 1 195 ? 41.287 -25.882 9.242 1.00 27.82 ? 195 PHE B C 1 ATOM 4867 O O . PHE B 1 195 ? 40.325 -25.838 10.024 1.00 27.72 ? 195 PHE B O 1 ATOM 4868 C CB . PHE B 1 195 ? 41.781 -23.772 7.921 1.00 25.70 ? 195 PHE B CB 1 ATOM 4869 C CG . PHE B 1 195 ? 40.273 -23.592 7.860 1.00 21.25 ? 195 PHE B CG 1 ATOM 4870 C CD1 . PHE B 1 195 ? 39.648 -22.620 8.616 1.00 19.47 ? 195 PHE B CD1 1 ATOM 4871 C CD2 . PHE B 1 195 ? 39.482 -24.437 7.069 1.00 20.34 ? 195 PHE B CD2 1 ATOM 4872 C CE1 . PHE B 1 195 ? 38.212 -22.456 8.576 1.00 18.16 ? 195 PHE B CE1 1 ATOM 4873 C CE2 . PHE B 1 195 ? 38.103 -24.307 7.026 1.00 14.92 ? 195 PHE B CE2 1 ATOM 4874 C CZ . PHE B 1 195 ? 37.472 -23.299 7.778 1.00 17.03 ? 195 PHE B CZ 1 ATOM 4875 N N . GLU B 1 196 ? 41.543 -26.956 8.510 1.00 29.47 ? 196 GLU B N 1 ATOM 4876 C CA . GLU B 1 196 ? 40.723 -28.139 8.678 1.00 32.16 ? 196 GLU B CA 1 ATOM 4877 C C . GLU B 1 196 ? 40.790 -28.674 10.135 1.00 33.60 ? 196 GLU B C 1 ATOM 4878 O O . GLU B 1 196 ? 39.826 -29.244 10.656 1.00 33.91 ? 196 GLU B O 1 ATOM 4879 C CB . GLU B 1 196 ? 41.113 -29.198 7.625 1.00 32.51 ? 196 GLU B CB 1 ATOM 4880 C CG . GLU B 1 196 ? 40.870 -28.723 6.149 1.00 33.07 ? 196 GLU B CG 1 ATOM 4881 C CD . GLU B 1 196 ? 39.371 -28.530 5.829 1.00 34.67 ? 196 GLU B CD 1 ATOM 4882 O OE1 . GLU B 1 196 ? 38.563 -29.378 6.304 1.00 35.93 ? 196 GLU B OE1 1 ATOM 4883 O OE2 . GLU B 1 196 ? 39.004 -27.549 5.118 1.00 33.21 ? 196 GLU B OE2 1 ATOM 4884 N N . ASP B 1 197 ? 41.919 -28.444 10.800 1.00 34.39 ? 197 ASP B N 1 ATOM 4885 C CA . ASP B 1 197 ? 42.106 -28.945 12.153 1.00 35.97 ? 197 ASP B CA 1 ATOM 4886 C C . ASP B 1 197 ? 41.513 -28.074 13.271 1.00 35.78 ? 197 ASP B C 1 ATOM 4887 O O . ASP B 1 197 ? 41.341 -28.575 14.385 1.00 35.98 ? 197 ASP B O 1 ATOM 4888 C CB . ASP B 1 197 ? 43.599 -29.255 12.417 1.00 36.48 ? 197 ASP B CB 1 ATOM 4889 C CG . ASP B 1 197 ? 44.016 -30.633 11.891 1.00 39.10 ? 197 ASP B CG 1 ATOM 4890 O OD1 . ASP B 1 197 ? 43.121 -31.409 11.476 1.00 43.35 ? 197 ASP B OD1 1 ATOM 4891 O OD2 . ASP B 1 197 ? 45.232 -30.940 11.888 1.00 42.44 ? 197 ASP B OD2 1 ATOM 4892 N N . SER B 1 198 ? 41.187 -26.810 12.955 1.00 34.93 ? 198 SER B N 1 ATOM 4893 C CA . SER B 1 198 ? 40.691 -25.789 13.917 1.00 34.52 ? 198 SER B CA 1 ATOM 4894 C C . SER B 1 198 ? 39.582 -26.323 14.825 1.00 34.98 ? 198 SER B C 1 ATOM 4895 O O . SER B 1 198 ? 38.789 -27.169 14.415 1.00 34.45 ? 198 SER B O 1 ATOM 4896 C CB . SER B 1 198 ? 40.164 -24.533 13.161 1.00 34.69 ? 198 SER B CB 1 ATOM 4897 O OG . SER B 1 198 ? 39.670 -23.477 13.994 1.00 33.45 ? 198 SER B OG 1 ATOM 4898 N N . GLU B 1 199 ? 39.515 -25.801 16.053 1.00 34.46 ? 199 GLU B N 1 ATOM 4899 C CA . GLU B 1 199 ? 38.463 -26.199 16.972 1.00 35.24 ? 199 GLU B CA 1 ATOM 4900 C C . GLU B 1 199 ? 37.773 -24.968 17.548 1.00 34.02 ? 199 GLU B C 1 ATOM 4901 O O . GLU B 1 199 ? 36.896 -25.084 18.400 1.00 35.31 ? 199 GLU B O 1 ATOM 4902 C CB . GLU B 1 199 ? 39.020 -27.093 18.103 1.00 35.96 ? 199 GLU B CB 1 ATOM 4903 C CG . GLU B 1 199 ? 38.831 -28.604 17.892 1.00 43.56 ? 199 GLU B CG 1 ATOM 4904 C CD . GLU B 1 199 ? 39.683 -29.490 18.870 1.00 51.50 ? 199 GLU B CD 1 ATOM 4905 O OE1 . GLU B 1 199 ? 40.345 -28.910 19.794 1.00 52.96 ? 199 GLU B OE1 1 ATOM 4906 O OE2 . GLU B 1 199 ? 39.682 -30.755 18.699 1.00 49.86 ? 199 GLU B OE2 1 ATOM 4907 N N . LEU B 1 200 ? 38.173 -23.794 17.079 1.00 32.41 ? 200 LEU B N 1 ATOM 4908 C CA . LEU B 1 200 ? 37.613 -22.533 17.531 1.00 30.75 ? 200 LEU B CA 1 ATOM 4909 C C . LEU B 1 200 ? 36.069 -22.506 17.525 1.00 30.25 ? 200 LEU B C 1 ATOM 4910 O O . LEU B 1 200 ? 35.467 -21.962 18.445 1.00 30.22 ? 200 LEU B O 1 ATOM 4911 C CB . LEU B 1 200 ? 38.207 -21.369 16.737 1.00 29.80 ? 200 LEU B CB 1 ATOM 4912 C CG . LEU B 1 200 ? 37.700 -19.984 17.189 1.00 30.72 ? 200 LEU B CG 1 ATOM 4913 C CD1 . LEU B 1 200 ? 38.033 -19.664 18.663 1.00 29.63 ? 200 LEU B CD1 1 ATOM 4914 C CD2 . LEU B 1 200 ? 38.190 -18.845 16.275 1.00 28.53 ? 200 LEU B CD2 1 ATOM 4915 N N . ALA B 1 201 ? 35.433 -23.106 16.519 1.00 29.52 ? 201 ALA B N 1 ATOM 4916 C CA . ALA B 1 201 ? 33.979 -23.033 16.411 1.00 30.13 ? 201 ALA B CA 1 ATOM 4917 C C . ALA B 1 201 ? 33.300 -23.872 17.471 1.00 30.05 ? 201 ALA B C 1 ATOM 4918 O O . ALA B 1 201 ? 32.295 -23.462 18.026 1.00 28.82 ? 201 ALA B O 1 ATOM 4919 C CB . ALA B 1 201 ? 33.474 -23.438 15.008 1.00 30.18 ? 201 ALA B CB 1 ATOM 4920 N N . ASP B 1 202 ? 33.862 -25.055 17.727 1.00 31.68 ? 202 ASP B N 1 ATOM 4921 C CA . ASP B 1 202 ? 33.355 -25.986 18.759 1.00 32.43 ? 202 ASP B CA 1 ATOM 4922 C C . ASP B 1 202 ? 33.360 -25.333 20.153 1.00 31.96 ? 202 ASP B C 1 ATOM 4923 O O . ASP B 1 202 ? 32.361 -25.385 20.912 1.00 32.01 ? 202 ASP B O 1 ATOM 4924 C CB . ASP B 1 202 ? 34.145 -27.301 18.725 1.00 32.33 ? 202 ASP B CB 1 ATOM 4925 C CG . ASP B 1 202 ? 33.799 -28.171 17.519 1.00 36.68 ? 202 ASP B CG 1 ATOM 4926 O OD1 . ASP B 1 202 ? 32.704 -27.977 16.957 1.00 40.88 ? 202 ASP B OD1 1 ATOM 4927 O OD2 . ASP B 1 202 ? 34.606 -29.066 17.121 1.00 40.84 ? 202 ASP B OD2 1 ATOM 4928 N N . THR B 1 203 ? 34.479 -24.698 20.470 1.00 31.45 ? 203 THR B N 1 ATOM 4929 C CA . THR B 1 203 ? 34.624 -23.964 21.718 1.00 31.78 ? 203 THR B CA 1 ATOM 4930 C C . THR B 1 203 ? 33.545 -22.899 21.893 1.00 31.89 ? 203 THR B C 1 ATOM 4931 O O . THR B 1 203 ? 32.821 -22.895 22.905 1.00 31.75 ? 203 THR B O 1 ATOM 4932 C CB . THR B 1 203 ? 35.974 -23.283 21.768 1.00 31.57 ? 203 THR B CB 1 ATOM 4933 O OG1 . THR B 1 203 ? 36.969 -24.298 21.751 1.00 32.95 ? 203 THR B OG1 1 ATOM 4934 C CG2 . THR B 1 203 ? 36.150 -22.485 23.069 1.00 33.10 ? 203 THR B CG2 1 ATOM 4935 N N . VAL B 1 204 ? 33.469 -21.982 20.920 1.00 32.08 ? 204 VAL B N 1 ATOM 4936 C CA . VAL B 1 204 ? 32.443 -20.950 20.893 1.00 31.33 ? 204 VAL B CA 1 ATOM 4937 C C . VAL B 1 204 ? 31.040 -21.533 20.936 1.00 31.01 ? 204 VAL B C 1 ATOM 4938 O O . VAL B 1 204 ? 30.194 -21.026 21.658 1.00 30.63 ? 204 VAL B O 1 ATOM 4939 C CB . VAL B 1 204 ? 32.552 -20.092 19.646 1.00 32.04 ? 204 VAL B CB 1 ATOM 4940 C CG1 . VAL B 1 204 ? 31.417 -19.080 19.609 1.00 31.92 ? 204 VAL B CG1 1 ATOM 4941 C CG2 . VAL B 1 204 ? 33.915 -19.407 19.571 1.00 30.90 ? 204 VAL B CG2 1 ATOM 4942 N N . GLU B 1 205 ? 30.789 -22.601 20.186 1.00 30.70 ? 205 GLU B N 1 ATOM 4943 C CA . GLU B 1 205 ? 29.499 -23.225 20.223 1.00 30.72 ? 205 GLU B CA 1 ATOM 4944 C C . GLU B 1 205 ? 29.173 -23.613 21.686 1.00 30.79 ? 205 GLU B C 1 ATOM 4945 O O . GLU B 1 205 ? 28.086 -23.276 22.203 1.00 30.31 ? 205 GLU B O 1 ATOM 4946 C CB . GLU B 1 205 ? 29.424 -24.470 19.316 1.00 30.60 ? 205 GLU B CB 1 ATOM 4947 C CG . GLU B 1 205 ? 28.174 -25.352 19.626 1.00 33.19 ? 205 GLU B CG 1 ATOM 4948 C CD . GLU B 1 205 ? 27.770 -26.375 18.541 1.00 35.95 ? 205 GLU B CD 1 ATOM 4949 O OE1 . GLU B 1 205 ? 28.602 -26.752 17.702 1.00 36.38 ? 205 GLU B OE1 1 ATOM 4950 O OE2 . GLU B 1 205 ? 26.593 -26.815 18.550 1.00 37.39 ? 205 GLU B OE2 1 ATOM 4951 N N . ALA B 1 206 ? 30.079 -24.343 22.341 1.00 30.67 ? 206 ALA B N 1 ATOM 4952 C CA . ALA B 1 206 ? 29.790 -24.840 23.726 1.00 30.27 ? 206 ALA B CA 1 ATOM 4953 C C . ALA B 1 206 ? 29.703 -23.657 24.681 1.00 30.24 ? 206 ALA B C 1 ATOM 4954 O O . ALA B 1 206 ? 28.771 -23.566 25.465 1.00 29.72 ? 206 ALA B O 1 ATOM 4955 C CB . ALA B 1 206 ? 30.809 -25.864 24.207 1.00 29.47 ? 206 ALA B CB 1 ATOM 4956 N N . ASN B 1 207 ? 30.626 -22.707 24.598 1.00 30.29 ? 207 ASN B N 1 ATOM 4957 C CA . ASN B 1 207 ? 30.515 -21.606 25.552 1.00 30.96 ? 207 ASN B CA 1 ATOM 4958 C C . ASN B 1 207 ? 29.146 -20.949 25.446 1.00 31.36 ? 207 ASN B C 1 ATOM 4959 O O . ASN B 1 207 ? 28.464 -20.799 26.481 1.00 32.41 ? 207 ASN B O 1 ATOM 4960 C CB . ASN B 1 207 ? 31.672 -20.587 25.503 1.00 31.92 ? 207 ASN B CB 1 ATOM 4961 C CG . ASN B 1 207 ? 33.100 -21.246 25.747 1.00 35.59 ? 207 ASN B CG 1 ATOM 4962 O OD1 . ASN B 1 207 ? 33.227 -22.430 26.148 1.00 39.27 ? 207 ASN B OD1 1 ATOM 4963 N ND2 . ASN B 1 207 ? 34.152 -20.483 25.466 1.00 36.05 ? 207 ASN B ND2 1 ATOM 4964 N N . PHE B 1 208 ? 28.700 -20.604 24.224 1.00 30.20 ? 208 PHE B N 1 ATOM 4965 C CA . PHE B 1 208 ? 27.392 -19.960 24.074 1.00 28.25 ? 208 PHE B CA 1 ATOM 4966 C C . PHE B 1 208 ? 26.225 -20.862 24.360 1.00 27.68 ? 208 PHE B C 1 ATOM 4967 O O . PHE B 1 208 ? 25.234 -20.379 24.900 1.00 25.95 ? 208 PHE B O 1 ATOM 4968 C CB . PHE B 1 208 ? 27.186 -19.319 22.716 1.00 28.30 ? 208 PHE B CB 1 ATOM 4969 C CG . PHE B 1 208 ? 25.921 -18.494 22.620 1.00 27.49 ? 208 PHE B CG 1 ATOM 4970 C CD1 . PHE B 1 208 ? 25.848 -17.215 23.186 1.00 24.78 ? 208 PHE B CD1 1 ATOM 4971 C CD2 . PHE B 1 208 ? 24.815 -18.967 21.923 1.00 28.25 ? 208 PHE B CD2 1 ATOM 4972 C CE1 . PHE B 1 208 ? 24.721 -16.459 23.093 1.00 22.49 ? 208 PHE B CE1 1 ATOM 4973 C CE2 . PHE B 1 208 ? 23.645 -18.170 21.829 1.00 26.62 ? 208 PHE B CE2 1 ATOM 4974 C CZ . PHE B 1 208 ? 23.617 -16.924 22.418 1.00 22.06 ? 208 PHE B CZ 1 ATOM 4975 N N . THR B 1 209 ? 26.305 -22.142 23.992 1.00 28.02 ? 209 THR B N 1 ATOM 4976 C CA . THR B 1 209 ? 25.156 -22.988 24.255 1.00 29.99 ? 209 THR B CA 1 ATOM 4977 C C . THR B 1 209 ? 24.931 -23.135 25.761 1.00 31.01 ? 209 THR B C 1 ATOM 4978 O O . THR B 1 209 ? 23.776 -23.187 26.223 1.00 31.15 ? 209 THR B O 1 ATOM 4979 C CB . THR B 1 209 ? 25.093 -24.377 23.507 1.00 30.68 ? 209 THR B CB 1 ATOM 4980 O OG1 . THR B 1 209 ? 25.876 -25.353 24.170 1.00 32.12 ? 209 THR B OG1 1 ATOM 4981 C CG2 . THR B 1 209 ? 25.508 -24.299 22.057 1.00 31.15 ? 209 THR B CG2 1 ATOM 4982 N N . ALA B 1 210 ? 26.028 -23.130 26.527 1.00 31.86 ? 210 ALA B N 1 ATOM 4983 C CA . ALA B 1 210 ? 25.943 -23.169 27.988 1.00 32.86 ? 210 ALA B CA 1 ATOM 4984 C C . ALA B 1 210 ? 25.237 -21.951 28.610 1.00 33.17 ? 210 ALA B C 1 ATOM 4985 O O . ALA B 1 210 ? 24.780 -22.048 29.747 1.00 33.39 ? 210 ALA B O 1 ATOM 4986 C CB . ALA B 1 210 ? 27.304 -23.429 28.631 1.00 33.13 ? 210 ALA B CB 1 ATOM 4987 N N . THR B 1 211 ? 25.065 -20.852 27.864 1.00 32.50 ? 211 THR B N 1 ATOM 4988 C CA . THR B 1 211 ? 24.326 -19.718 28.424 1.00 32.52 ? 211 THR B CA 1 ATOM 4989 C C . THR B 1 211 ? 22.802 -19.715 28.255 1.00 32.17 ? 211 THR B C 1 ATOM 4990 O O . THR B 1 211 ? 22.132 -18.852 28.868 1.00 32.51 ? 211 THR B O 1 ATOM 4991 C CB . THR B 1 211 ? 24.795 -18.335 27.934 1.00 32.82 ? 211 THR B CB 1 ATOM 4992 O OG1 . THR B 1 211 ? 24.045 -17.967 26.768 1.00 35.35 ? 211 THR B OG1 1 ATOM 4993 C CG2 . THR B 1 211 ? 26.323 -18.269 27.676 1.00 33.99 ? 211 THR B CG2 1 ATOM 4994 N N . PHE B 1 212 ? 22.242 -20.592 27.412 1.00 30.69 ? 212 PHE B N 1 ATOM 4995 C CA . PHE B 1 212 ? 20.766 -20.582 27.221 1.00 28.91 ? 212 PHE B CA 1 ATOM 4996 C C . PHE B 1 212 ? 20.164 -21.958 27.106 1.00 27.35 ? 212 PHE B C 1 ATOM 4997 O O . PHE B 1 212 ? 19.005 -22.132 27.383 1.00 26.90 ? 212 PHE B O 1 ATOM 4998 C CB . PHE B 1 212 ? 20.328 -19.722 26.016 1.00 29.04 ? 212 PHE B CB 1 ATOM 4999 C CG . PHE B 1 212 ? 20.518 -20.399 24.680 1.00 28.69 ? 212 PHE B CG 1 ATOM 5000 C CD1 . PHE B 1 212 ? 21.749 -20.355 24.017 1.00 26.56 ? 212 PHE B CD1 1 ATOM 5001 C CD2 . PHE B 1 212 ? 19.460 -21.057 24.082 1.00 29.08 ? 212 PHE B CD2 1 ATOM 5002 C CE1 . PHE B 1 212 ? 21.923 -20.973 22.807 1.00 27.48 ? 212 PHE B CE1 1 ATOM 5003 C CE2 . PHE B 1 212 ? 19.613 -21.687 22.854 1.00 28.66 ? 212 PHE B CE2 1 ATOM 5004 C CZ . PHE B 1 212 ? 20.843 -21.661 22.218 1.00 28.85 ? 212 PHE B CZ 1 ATOM 5005 N N . VAL B 1 213 ? 20.942 -22.942 26.692 1.00 26.09 ? 213 VAL B N 1 ATOM 5006 C CA . VAL B 1 213 ? 20.359 -24.301 26.567 1.00 25.93 ? 213 VAL B CA 1 ATOM 5007 C C . VAL B 1 213 ? 19.932 -24.999 27.897 1.00 26.90 ? 213 VAL B C 1 ATOM 5008 O O . VAL B 1 213 ? 18.887 -25.660 27.933 1.00 26.67 ? 213 VAL B O 1 ATOM 5009 C CB . VAL B 1 213 ? 21.191 -25.194 25.632 1.00 24.60 ? 213 VAL B CB 1 ATOM 5010 C CG1 . VAL B 1 213 ? 20.635 -26.572 25.545 1.00 23.16 ? 213 VAL B CG1 1 ATOM 5011 C CG2 . VAL B 1 213 ? 21.198 -24.588 24.248 1.00 23.72 ? 213 VAL B CG2 1 ATOM 5012 N N . PRO B 1 214 ? 20.742 -24.852 28.985 1.00 28.19 ? 214 PRO B N 1 ATOM 5013 C CA . PRO B 1 214 ? 20.379 -25.471 30.293 1.00 27.80 ? 214 PRO B CA 1 ATOM 5014 C C . PRO B 1 214 ? 18.935 -25.207 30.748 1.00 27.67 ? 214 PRO B C 1 ATOM 5015 O O . PRO B 1 214 ? 18.238 -26.149 31.116 1.00 26.42 ? 214 PRO B O 1 ATOM 5016 C CB . PRO B 1 214 ? 21.391 -24.847 31.252 1.00 27.10 ? 214 PRO B CB 1 ATOM 5017 C CG . PRO B 1 214 ? 22.677 -24.747 30.352 1.00 28.06 ? 214 PRO B CG 1 ATOM 5018 C CD . PRO B 1 214 ? 22.105 -24.240 29.041 1.00 27.76 ? 214 PRO B CD 1 ATOM 5019 N N . SER B 1 215 ? 18.477 -23.960 30.690 1.00 28.79 ? 215 SER B N 1 ATOM 5020 C CA . SER B 1 215 ? 17.080 -23.660 31.012 1.00 29.82 ? 215 SER B CA 1 ATOM 5021 C C . SER B 1 215 ? 16.111 -24.432 30.133 1.00 30.19 ? 215 SER B C 1 ATOM 5022 O O . SER B 1 215 ? 15.046 -24.870 30.602 1.00 30.83 ? 215 SER B O 1 ATOM 5023 C CB . SER B 1 215 ? 16.787 -22.192 30.797 1.00 29.93 ? 215 SER B CB 1 ATOM 5024 O OG . SER B 1 215 ? 17.546 -21.444 31.702 1.00 33.78 ? 215 SER B OG 1 ATOM 5025 N N . ILE B 1 216 ? 16.444 -24.580 28.854 1.00 29.47 ? 216 ILE B N 1 ATOM 5026 C CA . ILE B 1 216 ? 15.523 -25.297 27.981 1.00 29.15 ? 216 ILE B CA 1 ATOM 5027 C C . ILE B 1 216 ? 15.556 -26.745 28.383 1.00 28.98 ? 216 ILE B C 1 ATOM 5028 O O . ILE B 1 216 ? 14.505 -27.349 28.647 1.00 29.30 ? 216 ILE B O 1 ATOM 5029 C CB . ILE B 1 216 ? 15.852 -25.145 26.456 1.00 29.45 ? 216 ILE B CB 1 ATOM 5030 C CG1 . ILE B 1 216 ? 15.907 -23.657 26.069 1.00 28.19 ? 216 ILE B CG1 1 ATOM 5031 C CG2 . ILE B 1 216 ? 14.786 -25.919 25.624 1.00 25.80 ? 216 ILE B CG2 1 ATOM 5032 C CD1 . ILE B 1 216 ? 16.377 -23.393 24.672 1.00 29.08 ? 216 ILE B CD1 1 ATOM 5033 N N . ARG B 1 217 ? 16.762 -27.295 28.463 1.00 28.58 ? 217 ARG B N 1 ATOM 5034 C CA . ARG B 1 217 ? 16.934 -28.675 28.926 1.00 29.44 ? 217 ARG B CA 1 ATOM 5035 C C . ARG B 1 217 ? 16.098 -28.956 30.190 1.00 30.36 ? 217 ARG B C 1 ATOM 5036 O O . ARG B 1 217 ? 15.395 -29.957 30.273 1.00 31.24 ? 217 ARG B O 1 ATOM 5037 C CB . ARG B 1 217 ? 18.392 -28.965 29.148 1.00 28.55 ? 217 ARG B CB 1 ATOM 5038 C CG . ARG B 1 217 ? 18.773 -30.431 29.182 1.00 29.94 ? 217 ARG B CG 1 ATOM 5039 C CD . ARG B 1 217 ? 19.017 -30.921 30.635 1.00 30.06 ? 217 ARG B CD 1 ATOM 5040 N NE . ARG B 1 217 ? 19.810 -29.943 31.396 1.00 30.70 ? 217 ARG B NE 1 ATOM 5041 C CZ . ARG B 1 217 ? 19.643 -29.679 32.685 1.00 24.54 ? 217 ARG B CZ 1 ATOM 5042 N NH1 . ARG B 1 217 ? 18.692 -30.276 33.387 1.00 21.40 ? 217 ARG B NH1 1 ATOM 5043 N NH2 . ARG B 1 217 ? 20.365 -28.739 33.240 1.00 25.49 ? 217 ARG B NH2 1 ATOM 5044 N N . GLN B 1 218 ? 16.125 -28.042 31.140 1.00 30.70 ? 218 GLN B N 1 ATOM 5045 C CA . GLN B 1 218 ? 15.363 -28.223 32.362 1.00 32.80 ? 218 GLN B CA 1 ATOM 5046 C C . GLN B 1 218 ? 13.855 -28.326 32.123 1.00 31.61 ? 218 GLN B C 1 ATOM 5047 O O . GLN B 1 218 ? 13.234 -29.266 32.573 1.00 31.08 ? 218 GLN B O 1 ATOM 5048 C CB . GLN B 1 218 ? 15.682 -27.088 33.353 1.00 32.99 ? 218 GLN B CB 1 ATOM 5049 C CG . GLN B 1 218 ? 15.281 -27.356 34.805 1.00 37.88 ? 218 GLN B CG 1 ATOM 5050 C CD . GLN B 1 218 ? 16.114 -26.500 35.750 1.00 43.77 ? 218 GLN B CD 1 ATOM 5051 O OE1 . GLN B 1 218 ? 16.040 -25.261 35.716 1.00 43.52 ? 218 GLN B OE1 1 ATOM 5052 N NE2 . GLN B 1 218 ? 16.955 -27.159 36.559 1.00 44.16 ? 218 GLN B NE2 1 ATOM 5053 N N . ARG B 1 219 ? 13.286 -27.332 31.437 1.00 31.63 ? 219 ARG B N 1 ATOM 5054 C CA . ARG B 1 219 ? 11.879 -27.298 31.121 1.00 30.99 ? 219 ARG B CA 1 ATOM 5055 C C . ARG B 1 219 ? 11.454 -28.578 30.406 1.00 31.64 ? 219 ARG B C 1 ATOM 5056 O O . ARG B 1 219 ? 10.403 -29.150 30.719 1.00 32.03 ? 219 ARG B O 1 ATOM 5057 C CB . ARG B 1 219 ? 11.527 -26.045 30.324 1.00 30.38 ? 219 ARG B CB 1 ATOM 5058 C CG . ARG B 1 219 ? 10.001 -25.914 30.093 1.00 31.83 ? 219 ARG B CG 1 ATOM 5059 C CD . ARG B 1 219 ? 9.581 -24.740 29.199 1.00 31.96 ? 219 ARG B CD 1 ATOM 5060 N NE . ARG B 1 219 ? 10.118 -24.859 27.840 1.00 32.58 ? 219 ARG B NE 1 ATOM 5061 C CZ . ARG B 1 219 ? 11.083 -24.094 27.319 1.00 32.52 ? 219 ARG B CZ 1 ATOM 5062 N NH1 . ARG B 1 219 ? 11.666 -23.135 28.007 1.00 31.14 ? 219 ARG B NH1 1 ATOM 5063 N NH2 . ARG B 1 219 ? 11.471 -24.283 26.074 1.00 34.12 ? 219 ARG B NH2 1 ATOM 5064 N N . LEU B 1 220 ? 12.270 -29.054 29.470 1.00 31.10 ? 220 LEU B N 1 ATOM 5065 C CA . LEU B 1 220 ? 11.936 -30.289 28.771 1.00 31.15 ? 220 LEU B CA 1 ATOM 5066 C C . LEU B 1 220 ? 11.976 -31.522 29.659 1.00 31.60 ? 220 LEU B C 1 ATOM 5067 O O . LEU B 1 220 ? 11.176 -32.440 29.463 1.00 30.64 ? 220 LEU B O 1 ATOM 5068 C CB . LEU B 1 220 ? 12.828 -30.514 27.542 1.00 30.70 ? 220 LEU B CB 1 ATOM 5069 C CG . LEU B 1 220 ? 12.820 -29.487 26.409 1.00 31.51 ? 220 LEU B CG 1 ATOM 5070 C CD1 . LEU B 1 220 ? 13.888 -29.897 25.350 1.00 29.67 ? 220 LEU B CD1 1 ATOM 5071 C CD2 . LEU B 1 220 ? 11.404 -29.308 25.841 1.00 27.05 ? 220 LEU B CD2 1 ATOM 5072 N N . GLU B 1 221 ? 12.915 -31.568 30.609 1.00 31.78 ? 221 GLU B N 1 ATOM 5073 C CA . GLU B 1 221 ? 12.960 -32.707 31.519 1.00 33.76 ? 221 GLU B CA 1 ATOM 5074 C C . GLU B 1 221 ? 11.775 -32.664 32.488 1.00 34.05 ? 221 GLU B C 1 ATOM 5075 O O . GLU B 1 221 ? 11.171 -33.682 32.779 1.00 34.39 ? 221 GLU B O 1 ATOM 5076 C CB . GLU B 1 221 ? 14.311 -32.807 32.255 1.00 33.97 ? 221 GLU B CB 1 ATOM 5077 C CG . GLU B 1 221 ? 15.470 -33.277 31.362 1.00 34.60 ? 221 GLU B CG 1 ATOM 5078 C CD . GLU B 1 221 ? 16.815 -33.322 32.101 1.00 38.24 ? 221 GLU B CD 1 ATOM 5079 O OE1 . GLU B 1 221 ? 16.918 -32.757 33.204 1.00 39.81 ? 221 GLU B OE1 1 ATOM 5080 O OE2 . GLU B 1 221 ? 17.790 -33.929 31.594 1.00 38.33 ? 221 GLU B OE2 1 ATOM 5081 N N . ASN B 1 222 ? 11.436 -31.469 32.939 1.00 35.25 ? 222 ASN B N 1 ATOM 5082 C CA . ASN B 1 222 ? 10.204 -31.227 33.671 1.00 37.50 ? 222 ASN B CA 1 ATOM 5083 C C . ASN B 1 222 ? 8.929 -31.690 32.982 1.00 37.92 ? 222 ASN B C 1 ATOM 5084 O O . ASN B 1 222 ? 8.027 -32.238 33.636 1.00 37.49 ? 222 ASN B O 1 ATOM 5085 C CB . ASN B 1 222 ? 10.026 -29.745 33.919 1.00 38.03 ? 222 ASN B CB 1 ATOM 5086 C CG . ASN B 1 222 ? 10.326 -29.354 35.330 1.00 43.03 ? 222 ASN B CG 1 ATOM 5087 O OD1 . ASN B 1 222 ? 9.403 -29.338 36.188 1.00 48.05 ? 222 ASN B OD1 1 ATOM 5088 N ND2 . ASN B 1 222 ? 11.609 -29.027 35.613 1.00 43.67 ? 222 ASN B ND2 1 ATOM 5089 N N . ASP B 1 223 ? 8.823 -31.439 31.679 1.00 38.01 ? 223 ASP B N 1 ATOM 5090 C CA . ASP B 1 223 ? 7.537 -31.674 31.007 1.00 38.14 ? 223 ASP B CA 1 ATOM 5091 C C . ASP B 1 223 ? 7.419 -33.130 30.583 1.00 38.01 ? 223 ASP B C 1 ATOM 5092 O O . ASP B 1 223 ? 6.336 -33.700 30.560 1.00 38.00 ? 223 ASP B O 1 ATOM 5093 C CB . ASP B 1 223 ? 7.365 -30.733 29.826 1.00 37.73 ? 223 ASP B CB 1 ATOM 5094 C CG . ASP B 1 223 ? 7.270 -29.280 30.251 1.00 38.77 ? 223 ASP B CG 1 ATOM 5095 O OD1 . ASP B 1 223 ? 6.959 -29.010 31.417 1.00 39.87 ? 223 ASP B OD1 1 ATOM 5096 O OD2 . ASP B 1 223 ? 7.494 -28.380 29.422 1.00 41.53 ? 223 ASP B OD2 1 ATOM 5097 N N . LEU B 1 224 ? 8.560 -33.721 30.270 1.00 37.43 ? 224 LEU B N 1 ATOM 5098 C CA . LEU B 1 224 ? 8.621 -35.089 29.853 1.00 37.56 ? 224 LEU B CA 1 ATOM 5099 C C . LEU B 1 224 ? 9.253 -35.964 30.958 1.00 37.55 ? 224 LEU B C 1 ATOM 5100 O O . LEU B 1 224 ? 10.440 -36.334 30.884 1.00 37.25 ? 224 LEU B O 1 ATOM 5101 C CB . LEU B 1 224 ? 9.439 -35.175 28.553 1.00 37.60 ? 224 LEU B CB 1 ATOM 5102 C CG . LEU B 1 224 ? 8.852 -34.578 27.263 1.00 38.98 ? 224 LEU B CG 1 ATOM 5103 C CD1 . LEU B 1 224 ? 9.989 -34.057 26.341 1.00 36.48 ? 224 LEU B CD1 1 ATOM 5104 C CD2 . LEU B 1 224 ? 7.919 -35.631 26.548 1.00 35.32 ? 224 LEU B CD2 1 ATOM 5105 N N . SER B 1 225 ? 8.451 -36.297 31.967 1.00 37.76 ? 225 SER B N 1 ATOM 5106 C CA . SER B 1 225 ? 8.887 -37.135 33.083 1.00 38.15 ? 225 SER B CA 1 ATOM 5107 C C . SER B 1 225 ? 9.447 -38.464 32.664 1.00 37.40 ? 225 SER B C 1 ATOM 5108 O O . SER B 1 225 ? 8.765 -39.250 31.995 1.00 38.04 ? 225 SER B O 1 ATOM 5109 C CB . SER B 1 225 ? 7.719 -37.392 34.011 1.00 38.97 ? 225 SER B CB 1 ATOM 5110 O OG . SER B 1 225 ? 7.569 -36.270 34.873 1.00 42.91 ? 225 SER B OG 1 ATOM 5111 N N . GLY B 1 226 ? 10.680 -38.735 33.073 1.00 36.54 ? 226 GLY B N 1 ATOM 5112 C CA . GLY B 1 226 ? 11.322 -40.013 32.735 1.00 35.85 ? 226 GLY B CA 1 ATOM 5113 C C . GLY B 1 226 ? 12.448 -39.796 31.741 1.00 35.53 ? 226 GLY B C 1 ATOM 5114 O O . GLY B 1 226 ? 13.254 -40.707 31.454 1.00 36.47 ? 226 GLY B O 1 ATOM 5115 N N . VAL B 1 227 ? 12.526 -38.570 31.241 1.00 34.57 ? 227 VAL B N 1 ATOM 5116 C CA . VAL B 1 227 ? 13.432 -38.251 30.161 1.00 33.11 ? 227 VAL B CA 1 ATOM 5117 C C . VAL B 1 227 ? 14.617 -37.506 30.699 1.00 32.53 ? 227 VAL B C 1 ATOM 5118 O O . VAL B 1 227 ? 14.475 -36.605 31.513 1.00 31.72 ? 227 VAL B O 1 ATOM 5119 C CB . VAL B 1 227 ? 12.684 -37.454 29.037 1.00 33.51 ? 227 VAL B CB 1 ATOM 5120 C CG1 . VAL B 1 227 ? 13.501 -36.312 28.486 1.00 31.68 ? 227 VAL B CG1 1 ATOM 5121 C CG2 . VAL B 1 227 ? 12.182 -38.431 27.947 1.00 31.40 ? 227 VAL B CG2 1 ATOM 5122 N N . THR B 1 228 ? 15.796 -37.871 30.217 1.00 31.70 ? 228 THR B N 1 ATOM 5123 C CA . THR B 1 228 ? 16.999 -37.148 30.591 1.00 31.81 ? 228 THR B CA 1 ATOM 5124 C C . THR B 1 228 ? 17.798 -36.728 29.340 1.00 31.04 ? 228 THR B C 1 ATOM 5125 O O . THR B 1 228 ? 18.077 -37.550 28.479 1.00 31.25 ? 228 THR B O 1 ATOM 5126 C CB . THR B 1 228 ? 17.819 -37.971 31.645 1.00 32.54 ? 228 THR B CB 1 ATOM 5127 O OG1 . THR B 1 228 ? 19.179 -38.115 31.205 1.00 34.99 ? 228 THR B OG1 1 ATOM 5128 C CG2 . THR B 1 228 ? 17.206 -39.384 31.885 1.00 32.04 ? 228 THR B CG2 1 ATOM 5129 N N . LEU B 1 229 ? 18.108 -35.440 29.213 1.00 29.74 ? 229 LEU B N 1 ATOM 5130 C CA . LEU B 1 229 ? 18.655 -34.900 27.957 1.00 28.84 ? 229 LEU B CA 1 ATOM 5131 C C . LEU B 1 229 ? 19.983 -34.193 28.135 1.00 28.45 ? 229 LEU B C 1 ATOM 5132 O O . LEU B 1 229 ? 20.177 -33.494 29.153 1.00 28.15 ? 229 LEU B O 1 ATOM 5133 C CB . LEU B 1 229 ? 17.668 -33.870 27.336 1.00 28.48 ? 229 LEU B CB 1 ATOM 5134 C CG . LEU B 1 229 ? 16.291 -34.334 26.808 1.00 28.41 ? 229 LEU B CG 1 ATOM 5135 C CD1 . LEU B 1 229 ? 15.306 -33.159 26.614 1.00 24.42 ? 229 LEU B CD1 1 ATOM 5136 C CD2 . LEU B 1 229 ? 16.423 -35.209 25.540 1.00 22.98 ? 229 LEU B CD2 1 ATOM 5137 N N . THR B 1 230 ? 20.881 -34.313 27.150 1.00 27.82 ? 230 THR B N 1 ATOM 5138 C CA . THR B 1 230 ? 22.070 -33.444 27.166 1.00 27.45 ? 230 THR B CA 1 ATOM 5139 C C . THR B 1 230 ? 21.753 -32.099 26.508 1.00 28.13 ? 230 THR B C 1 ATOM 5140 O O . THR B 1 230 ? 20.779 -31.970 25.806 1.00 27.69 ? 230 THR B O 1 ATOM 5141 C CB . THR B 1 230 ? 23.257 -34.046 26.441 1.00 27.47 ? 230 THR B CB 1 ATOM 5142 O OG1 . THR B 1 230 ? 22.975 -34.104 25.035 1.00 26.53 ? 230 THR B OG1 1 ATOM 5143 C CG2 . THR B 1 230 ? 23.630 -35.435 27.033 1.00 26.16 ? 230 THR B CG2 1 ATOM 5144 N N . ASP B 1 231 ? 22.581 -31.100 26.742 1.00 28.53 ? 231 ASP B N 1 ATOM 5145 C CA . ASP B 1 231 ? 22.458 -29.870 26.008 1.00 29.76 ? 231 ASP B CA 1 ATOM 5146 C C . ASP B 1 231 ? 22.445 -30.130 24.495 1.00 29.67 ? 231 ASP B C 1 ATOM 5147 O O . ASP B 1 231 ? 21.643 -29.541 23.753 1.00 30.31 ? 231 ASP B O 1 ATOM 5148 C CB . ASP B 1 231 ? 23.564 -28.900 26.402 1.00 29.50 ? 231 ASP B CB 1 ATOM 5149 C CG . ASP B 1 231 ? 23.393 -28.340 27.856 1.00 32.46 ? 231 ASP B CG 1 ATOM 5150 O OD1 . ASP B 1 231 ? 22.298 -28.394 28.480 1.00 32.47 ? 231 ASP B OD1 1 ATOM 5151 O OD2 . ASP B 1 231 ? 24.388 -27.801 28.366 1.00 34.08 ? 231 ASP B OD2 1 ATOM 5152 N N . THR B 1 232 ? 23.303 -31.026 24.027 1.00 29.15 ? 232 THR B N 1 ATOM 5153 C CA . THR B 1 232 ? 23.426 -31.210 22.596 1.00 27.99 ? 232 THR B CA 1 ATOM 5154 C C . THR B 1 232 ? 22.130 -31.774 22.057 1.00 28.05 ? 232 THR B C 1 ATOM 5155 O O . THR B 1 232 ? 21.668 -31.365 21.004 1.00 28.49 ? 232 THR B O 1 ATOM 5156 C CB . THR B 1 232 ? 24.658 -32.042 22.226 1.00 28.30 ? 232 THR B CB 1 ATOM 5157 O OG1 . THR B 1 232 ? 25.828 -31.308 22.626 1.00 26.52 ? 232 THR B OG1 1 ATOM 5158 C CG2 . THR B 1 232 ? 24.728 -32.256 20.752 1.00 25.53 ? 232 THR B CG2 1 ATOM 5159 N N . GLU B 1 233 ? 21.508 -32.675 22.810 1.00 27.01 ? 233 GLU B N 1 ATOM 5160 C CA . GLU B 1 233 ? 20.274 -33.257 22.374 1.00 25.74 ? 233 GLU B CA 1 ATOM 5161 C C . GLU B 1 233 ? 19.181 -32.194 22.274 1.00 24.88 ? 233 GLU B C 1 ATOM 5162 O O . GLU B 1 233 ? 18.338 -32.276 21.406 1.00 24.75 ? 233 GLU B O 1 ATOM 5163 C CB . GLU B 1 233 ? 19.882 -34.430 23.260 1.00 25.76 ? 233 GLU B CB 1 ATOM 5164 C CG . GLU B 1 233 ? 20.885 -35.586 23.121 1.00 28.43 ? 233 GLU B CG 1 ATOM 5165 C CD . GLU B 1 233 ? 20.719 -36.683 24.189 1.00 28.79 ? 233 GLU B CD 1 ATOM 5166 O OE1 . GLU B 1 233 ? 20.307 -36.356 25.318 1.00 28.70 ? 233 GLU B OE1 1 ATOM 5167 O OE2 . GLU B 1 233 ? 20.980 -37.864 23.881 1.00 30.35 ? 233 GLU B OE2 1 ATOM 5168 N N . VAL B 1 234 ? 19.207 -31.187 23.133 1.00 23.64 ? 234 VAL B N 1 ATOM 5169 C CA . VAL B 1 234 ? 18.183 -30.181 23.059 1.00 23.39 ? 234 VAL B CA 1 ATOM 5170 C C . VAL B 1 234 ? 18.336 -29.453 21.733 1.00 23.34 ? 234 VAL B C 1 ATOM 5171 O O . VAL B 1 234 ? 17.343 -29.250 21.044 1.00 22.95 ? 234 VAL B O 1 ATOM 5172 C CB . VAL B 1 234 ? 18.255 -29.131 24.189 1.00 23.99 ? 234 VAL B CB 1 ATOM 5173 C CG1 . VAL B 1 234 ? 17.340 -27.919 23.857 1.00 22.81 ? 234 VAL B CG1 1 ATOM 5174 C CG2 . VAL B 1 234 ? 17.868 -29.747 25.493 1.00 24.06 ? 234 VAL B CG2 1 ATOM 5175 N N . THR B 1 235 ? 19.569 -29.064 21.372 1.00 21.96 ? 235 THR B N 1 ATOM 5176 C CA . THR B 1 235 ? 19.732 -28.497 20.070 1.00 21.95 ? 235 THR B CA 1 ATOM 5177 C C . THR B 1 235 ? 19.246 -29.469 18.915 1.00 22.10 ? 235 THR B C 1 ATOM 5178 O O . THR B 1 235 ? 18.681 -29.004 17.937 1.00 22.31 ? 235 THR B O 1 ATOM 5179 C CB . THR B 1 235 ? 21.108 -27.940 19.839 1.00 21.72 ? 235 THR B CB 1 ATOM 5180 O OG1 . THR B 1 235 ? 22.001 -29.018 19.723 1.00 20.54 ? 235 THR B OG1 1 ATOM 5181 C CG2 . THR B 1 235 ? 21.524 -27.057 20.981 1.00 21.43 ? 235 THR B CG2 1 ATOM 5182 N N . TYR B 1 236 ? 19.347 -30.782 19.064 1.00 21.92 ? 236 TYR B N 1 ATOM 5183 C CA . TYR B 1 236 ? 18.770 -31.681 18.037 1.00 21.97 ? 236 TYR B CA 1 ATOM 5184 C C . TYR B 1 236 ? 17.268 -31.486 17.856 1.00 22.77 ? 236 TYR B C 1 ATOM 5185 O O . TYR B 1 236 ? 16.792 -31.425 16.735 1.00 23.46 ? 236 TYR B O 1 ATOM 5186 C CB . TYR B 1 236 ? 19.076 -33.164 18.299 1.00 21.87 ? 236 TYR B CB 1 ATOM 5187 C CG . TYR B 1 236 ? 20.547 -33.542 18.289 1.00 22.77 ? 236 TYR B CG 1 ATOM 5188 C CD1 . TYR B 1 236 ? 21.480 -32.732 17.680 1.00 25.04 ? 236 TYR B CD1 1 ATOM 5189 C CD2 . TYR B 1 236 ? 20.997 -34.724 18.873 1.00 23.31 ? 236 TYR B CD2 1 ATOM 5190 C CE1 . TYR B 1 236 ? 22.849 -33.058 17.676 1.00 27.27 ? 236 TYR B CE1 1 ATOM 5191 C CE2 . TYR B 1 236 ? 22.378 -35.065 18.882 1.00 23.34 ? 236 TYR B CE2 1 ATOM 5192 C CZ . TYR B 1 236 ? 23.284 -34.213 18.256 1.00 27.34 ? 236 TYR B CZ 1 ATOM 5193 O OH . TYR B 1 236 ? 24.648 -34.449 18.185 1.00 31.00 ? 236 TYR B OH 1 ATOM 5194 N N . LEU B 1 237 ? 16.507 -31.393 18.944 1.00 23.14 ? 237 LEU B N 1 ATOM 5195 C CA . LEU B 1 237 ? 15.078 -31.143 18.842 1.00 22.87 ? 237 LEU B CA 1 ATOM 5196 C C . LEU B 1 237 ? 14.793 -29.729 18.331 1.00 23.56 ? 237 LEU B C 1 ATOM 5197 O O . LEU B 1 237 ? 13.704 -29.434 17.823 1.00 23.64 ? 237 LEU B O 1 ATOM 5198 C CB . LEU B 1 237 ? 14.411 -31.324 20.192 1.00 22.46 ? 237 LEU B CB 1 ATOM 5199 C CG . LEU B 1 237 ? 14.551 -32.676 20.869 1.00 20.87 ? 237 LEU B CG 1 ATOM 5200 C CD1 . LEU B 1 237 ? 14.075 -32.411 22.268 1.00 20.24 ? 237 LEU B CD1 1 ATOM 5201 C CD2 . LEU B 1 237 ? 13.726 -33.825 20.159 1.00 16.58 ? 237 LEU B CD2 1 ATOM 5202 N N . MET B 1 238 ? 15.764 -28.839 18.481 1.00 23.48 ? 238 MET B N 1 ATOM 5203 C CA . MET B 1 238 ? 15.624 -27.535 17.832 1.00 23.74 ? 238 MET B CA 1 ATOM 5204 C C . MET B 1 238 ? 15.823 -27.637 16.296 1.00 23.79 ? 238 MET B C 1 ATOM 5205 O O . MET B 1 238 ? 15.054 -27.077 15.525 1.00 22.98 ? 238 MET B O 1 ATOM 5206 C CB . MET B 1 238 ? 16.493 -26.455 18.506 1.00 23.34 ? 238 MET B CB 1 ATOM 5207 C CG . MET B 1 238 ? 15.969 -26.131 19.939 1.00 21.67 ? 238 MET B CG 1 ATOM 5208 S SD . MET B 1 238 ? 16.707 -24.720 20.750 1.00 23.03 ? 238 MET B SD 1 ATOM 5209 C CE . MET B 1 238 ? 15.742 -23.334 20.160 1.00 16.07 ? 238 MET B CE 1 ATOM 5210 N N . ASP B 1 239 ? 16.864 -28.347 15.885 1.00 24.13 ? 239 ASP B N 1 ATOM 5211 C CA . ASP B 1 239 ? 17.121 -28.609 14.492 1.00 25.07 ? 239 ASP B CA 1 ATOM 5212 C C . ASP B 1 239 ? 15.861 -29.222 13.801 1.00 25.82 ? 239 ASP B C 1 ATOM 5213 O O . ASP B 1 239 ? 15.510 -28.849 12.680 1.00 26.45 ? 239 ASP B O 1 ATOM 5214 C CB . ASP B 1 239 ? 18.258 -29.608 14.381 1.00 24.11 ? 239 ASP B CB 1 ATOM 5215 C CG . ASP B 1 239 ? 19.631 -29.036 14.755 1.00 23.38 ? 239 ASP B CG 1 ATOM 5216 O OD1 . ASP B 1 239 ? 19.829 -27.832 14.972 1.00 20.66 ? 239 ASP B OD1 1 ATOM 5217 O OD2 . ASP B 1 239 ? 20.553 -29.854 14.807 1.00 26.51 ? 239 ASP B OD2 1 ATOM 5218 N N . MET B 1 240 ? 15.166 -30.128 14.484 1.00 26.07 ? 240 MET B N 1 ATOM 5219 C CA . MET B 1 240 ? 14.079 -30.856 13.867 1.00 26.77 ? 240 MET B CA 1 ATOM 5220 C C . MET B 1 240 ? 12.920 -29.936 13.526 1.00 27.19 ? 240 MET B C 1 ATOM 5221 O O . MET B 1 240 ? 12.120 -30.252 12.659 1.00 26.82 ? 240 MET B O 1 ATOM 5222 C CB . MET B 1 240 ? 13.624 -31.975 14.779 1.00 27.23 ? 240 MET B CB 1 ATOM 5223 C CG . MET B 1 240 ? 14.583 -33.111 14.745 1.00 26.42 ? 240 MET B CG 1 ATOM 5224 S SD . MET B 1 240 ? 14.515 -33.995 13.153 1.00 28.71 ? 240 MET B SD 1 ATOM 5225 C CE . MET B 1 240 ? 12.811 -34.538 13.133 1.00 26.37 ? 240 MET B CE 1 ATOM 5226 N N . CYS B 1 241 ? 12.835 -28.793 14.199 1.00 26.34 ? 241 CYS B N 1 ATOM 5227 C CA . CYS B 1 241 ? 11.816 -27.832 13.855 1.00 27.57 ? 241 CYS B CA 1 ATOM 5228 C C . CYS B 1 241 ? 11.942 -27.335 12.373 1.00 28.04 ? 241 CYS B C 1 ATOM 5229 O O . CYS B 1 241 ? 10.962 -27.217 11.659 1.00 28.11 ? 241 CYS B O 1 ATOM 5230 C CB . CYS B 1 241 ? 11.813 -26.714 14.864 1.00 26.91 ? 241 CYS B CB 1 ATOM 5231 S SG . CYS B 1 241 ? 11.113 -25.170 14.315 1.00 29.33 ? 241 CYS B SG 1 ATOM 5232 N N . SER B 1 242 ? 13.155 -27.094 11.910 1.00 27.79 ? 242 SER B N 1 ATOM 5233 C CA . SER B 1 242 ? 13.357 -26.750 10.519 1.00 27.48 ? 242 SER B CA 1 ATOM 5234 C C . SER B 1 242 ? 13.171 -27.999 9.632 1.00 27.77 ? 242 SER B C 1 ATOM 5235 O O . SER B 1 242 ? 12.420 -27.950 8.678 1.00 27.74 ? 242 SER B O 1 ATOM 5236 C CB . SER B 1 242 ? 14.743 -26.169 10.313 1.00 26.54 ? 242 SER B CB 1 ATOM 5237 O OG . SER B 1 242 ? 15.082 -26.242 8.964 1.00 26.64 ? 242 SER B OG 1 ATOM 5238 N N . PHE B 1 243 ? 13.810 -29.114 9.971 1.00 27.29 ? 243 PHE B N 1 ATOM 5239 C CA . PHE B 1 243 ? 13.828 -30.239 9.065 1.00 27.85 ? 243 PHE B CA 1 ATOM 5240 C C . PHE B 1 243 ? 12.488 -30.927 8.985 1.00 29.36 ? 243 PHE B C 1 ATOM 5241 O O . PHE B 1 243 ? 12.187 -31.497 7.960 1.00 30.23 ? 243 PHE B O 1 ATOM 5242 C CB . PHE B 1 243 ? 14.897 -31.249 9.433 1.00 26.99 ? 243 PHE B CB 1 ATOM 5243 C CG . PHE B 1 243 ? 16.263 -30.813 9.113 1.00 25.93 ? 243 PHE B CG 1 ATOM 5244 C CD1 . PHE B 1 243 ? 16.801 -31.060 7.852 1.00 26.41 ? 243 PHE B CD1 1 ATOM 5245 C CD2 . PHE B 1 243 ? 17.061 -30.206 10.076 1.00 24.93 ? 243 PHE B CD2 1 ATOM 5246 C CE1 . PHE B 1 243 ? 18.117 -30.687 7.535 1.00 24.77 ? 243 PHE B CE1 1 ATOM 5247 C CE2 . PHE B 1 243 ? 18.386 -29.821 9.778 1.00 25.15 ? 243 PHE B CE2 1 ATOM 5248 C CZ . PHE B 1 243 ? 18.913 -30.033 8.490 1.00 24.03 ? 243 PHE B CZ 1 ATOM 5249 N N . ASP B 1 244 ? 11.692 -30.898 10.051 1.00 30.13 ? 244 ASP B N 1 ATOM 5250 C CA . ASP B 1 244 ? 10.334 -31.445 10.023 1.00 30.92 ? 244 ASP B CA 1 ATOM 5251 C C . ASP B 1 244 ? 9.341 -30.473 9.357 1.00 32.74 ? 244 ASP B C 1 ATOM 5252 O O . ASP B 1 244 ? 8.236 -30.870 8.950 1.00 33.03 ? 244 ASP B O 1 ATOM 5253 C CB . ASP B 1 244 ? 9.866 -31.787 11.444 1.00 30.02 ? 244 ASP B CB 1 ATOM 5254 C CG . ASP B 1 244 ? 8.582 -32.644 11.471 1.00 28.39 ? 244 ASP B CG 1 ATOM 5255 O OD1 . ASP B 1 244 ? 8.590 -33.805 10.985 1.00 26.10 ? 244 ASP B OD1 1 ATOM 5256 O OD2 . ASP B 1 244 ? 7.562 -32.148 11.982 1.00 27.74 ? 244 ASP B OD2 1 ATOM 5257 N N . THR B 1 245 ? 9.701 -29.197 9.258 1.00 34.09 ? 245 THR B N 1 ATOM 5258 C CA . THR B 1 245 ? 8.814 -28.266 8.560 1.00 35.30 ? 245 THR B CA 1 ATOM 5259 C C . THR B 1 245 ? 8.968 -28.428 7.032 1.00 36.99 ? 245 THR B C 1 ATOM 5260 O O . THR B 1 245 ? 7.985 -28.661 6.304 1.00 37.44 ? 245 THR B O 1 ATOM 5261 C CB . THR B 1 245 ? 9.030 -26.822 9.011 1.00 35.16 ? 245 THR B CB 1 ATOM 5262 O OG1 . THR B 1 245 ? 8.671 -26.727 10.380 1.00 33.89 ? 245 THR B OG1 1 ATOM 5263 C CG2 . THR B 1 245 ? 8.130 -25.858 8.247 1.00 34.95 ? 245 THR B CG2 1 ATOM 5264 N N . ILE B 1 246 ? 10.210 -28.390 6.570 1.00 37.80 ? 246 ILE B N 1 ATOM 5265 C CA . ILE B 1 246 ? 10.474 -28.188 5.169 1.00 38.64 ? 246 ILE B CA 1 ATOM 5266 C C . ILE B 1 246 ? 10.798 -29.452 4.369 1.00 40.12 ? 246 ILE B C 1 ATOM 5267 O O . ILE B 1 246 ? 11.189 -29.373 3.206 1.00 40.88 ? 246 ILE B O 1 ATOM 5268 C CB . ILE B 1 246 ? 11.491 -27.065 4.997 1.00 38.13 ? 246 ILE B CB 1 ATOM 5269 C CG1 . ILE B 1 246 ? 12.911 -27.505 5.314 1.00 37.76 ? 246 ILE B CG1 1 ATOM 5270 C CG2 . ILE B 1 246 ? 11.126 -25.877 5.873 1.00 36.97 ? 246 ILE B CG2 1 ATOM 5271 C CD1 . ILE B 1 246 ? 13.822 -26.289 5.399 1.00 35.19 ? 246 ILE B CD1 1 ATOM 5272 N N . SER B 1 247 ? 10.603 -30.605 4.999 1.00 41.70 ? 247 SER B N 1 ATOM 5273 C CA . SER B 1 247 ? 10.727 -31.925 4.378 1.00 44.00 ? 247 SER B CA 1 ATOM 5274 C C . SER B 1 247 ? 9.403 -32.476 3.909 1.00 45.03 ? 247 SER B C 1 ATOM 5275 O O . SER B 1 247 ? 9.349 -33.473 3.214 1.00 46.33 ? 247 SER B O 1 ATOM 5276 C CB . SER B 1 247 ? 11.249 -32.924 5.400 1.00 43.88 ? 247 SER B CB 1 ATOM 5277 O OG . SER B 1 247 ? 12.552 -32.566 5.819 1.00 46.55 ? 247 SER B OG 1 ATOM 5278 N N . THR B 1 248 ? 8.328 -31.830 4.292 1.00 46.53 ? 248 THR B N 1 ATOM 5279 C CA . THR B 1 248 ? 7.026 -32.416 4.136 1.00 48.23 ? 248 THR B CA 1 ATOM 5280 C C . THR B 1 248 ? 6.227 -31.673 3.071 1.00 48.57 ? 248 THR B C 1 ATOM 5281 O O . THR B 1 248 ? 6.629 -30.589 2.629 1.00 48.57 ? 248 THR B O 1 ATOM 5282 C CB . THR B 1 248 ? 6.277 -32.324 5.473 1.00 48.81 ? 248 THR B CB 1 ATOM 5283 O OG1 . THR B 1 248 ? 5.067 -33.081 5.378 1.00 50.68 ? 248 THR B OG1 1 ATOM 5284 C CG2 . THR B 1 248 ? 5.965 -30.846 5.811 1.00 48.60 ? 248 THR B CG2 1 ATOM 5285 N N . SER B 1 249 ? 5.098 -32.269 2.674 1.00 48.77 ? 249 SER B N 1 ATOM 5286 C CA . SER B 1 249 ? 4.148 -31.646 1.741 1.00 48.68 ? 249 SER B CA 1 ATOM 5287 C C . SER B 1 249 ? 3.577 -30.346 2.314 1.00 47.41 ? 249 SER B C 1 ATOM 5288 O O . SER B 1 249 ? 3.278 -29.407 1.562 1.00 46.80 ? 249 SER B O 1 ATOM 5289 C CB . SER B 1 249 ? 2.993 -32.616 1.457 1.00 49.52 ? 249 SER B CB 1 ATOM 5290 O OG . SER B 1 249 ? 2.276 -32.919 2.666 1.00 51.36 ? 249 SER B OG 1 ATOM 5291 N N . THR B 1 250 ? 3.437 -30.303 3.645 1.00 46.02 ? 250 THR B N 1 ATOM 5292 C CA . THR B 1 250 ? 2.846 -29.153 4.319 1.00 45.25 ? 250 THR B CA 1 ATOM 5293 C C . THR B 1 250 ? 3.816 -27.975 4.595 1.00 44.41 ? 250 THR B C 1 ATOM 5294 O O . THR B 1 250 ? 3.552 -27.172 5.497 1.00 43.60 ? 250 THR B O 1 ATOM 5295 C CB . THR B 1 250 ? 2.127 -29.574 5.634 1.00 45.78 ? 250 THR B CB 1 ATOM 5296 O OG1 . THR B 1 250 ? 2.960 -30.467 6.397 1.00 46.16 ? 250 THR B OG1 1 ATOM 5297 C CG2 . THR B 1 250 ? 0.770 -30.248 5.339 1.00 47.33 ? 250 THR B CG2 1 ATOM 5298 N N . VAL B 1 251 ? 4.901 -27.849 3.810 1.00 43.83 ? 251 VAL B N 1 ATOM 5299 C CA . VAL B 1 251 ? 5.907 -26.796 4.026 1.00 43.90 ? 251 VAL B CA 1 ATOM 5300 C C . VAL B 1 251 ? 5.272 -25.439 4.201 1.00 44.38 ? 251 VAL B C 1 ATOM 5301 O O . VAL B 1 251 ? 5.716 -24.642 5.026 1.00 43.62 ? 251 VAL B O 1 ATOM 5302 C CB . VAL B 1 251 ? 6.817 -26.556 2.819 1.00 43.93 ? 251 VAL B CB 1 ATOM 5303 C CG1 . VAL B 1 251 ? 8.124 -25.913 3.257 1.00 43.03 ? 251 VAL B CG1 1 ATOM 5304 C CG2 . VAL B 1 251 ? 6.971 -27.748 1.959 1.00 44.02 ? 251 VAL B CG2 1 ATOM 5305 N N . ASP B 1 252 ? 4.249 -25.185 3.373 1.00 45.58 ? 252 ASP B N 1 ATOM 5306 C CA . ASP B 1 252 ? 3.609 -23.865 3.208 1.00 45.91 ? 252 ASP B CA 1 ATOM 5307 C C . ASP B 1 252 ? 2.474 -23.633 4.184 1.00 45.28 ? 252 ASP B C 1 ATOM 5308 O O . ASP B 1 252 ? 2.106 -22.490 4.439 1.00 45.31 ? 252 ASP B O 1 ATOM 5309 C CB . ASP B 1 252 ? 3.108 -23.688 1.754 1.00 46.42 ? 252 ASP B CB 1 ATOM 5310 C CG . ASP B 1 252 ? 4.263 -23.530 0.744 1.00 49.91 ? 252 ASP B CG 1 ATOM 5311 O OD1 . ASP B 1 252 ? 5.199 -22.749 1.060 1.00 50.66 ? 252 ASP B OD1 1 ATOM 5312 O OD2 . ASP B 1 252 ? 4.246 -24.177 -0.351 1.00 51.53 ? 252 ASP B OD2 1 ATOM 5313 N N . THR B 1 253 ? 1.905 -24.711 4.720 1.00 45.03 ? 253 THR B N 1 ATOM 5314 C CA . THR B 1 253 ? 0.664 -24.589 5.505 1.00 45.45 ? 253 THR B CA 1 ATOM 5315 C C . THR B 1 253 ? 0.858 -24.751 7.022 1.00 44.99 ? 253 THR B C 1 ATOM 5316 O O . THR B 1 253 ? 0.216 -24.053 7.797 1.00 45.17 ? 253 THR B O 1 ATOM 5317 C CB . THR B 1 253 ? -0.458 -25.560 4.997 1.00 45.48 ? 253 THR B CB 1 ATOM 5318 O OG1 . THR B 1 253 ? -0.086 -26.928 5.241 1.00 46.00 ? 253 THR B OG1 1 ATOM 5319 C CG2 . THR B 1 253 ? -0.697 -25.358 3.499 1.00 46.48 ? 253 THR B CG2 1 ATOM 5320 N N . LYS B 1 254 ? 1.747 -25.672 7.425 1.00 44.53 ? 254 LYS B N 1 ATOM 5321 C CA . LYS B 1 254 ? 1.973 -26.018 8.850 1.00 43.28 ? 254 LYS B CA 1 ATOM 5322 C C . LYS B 1 254 ? 3.450 -25.931 9.253 1.00 41.97 ? 254 LYS B C 1 ATOM 5323 O O . LYS B 1 254 ? 4.335 -26.503 8.594 1.00 41.33 ? 254 LYS B O 1 ATOM 5324 C CB . LYS B 1 254 ? 1.414 -27.418 9.203 1.00 43.55 ? 254 LYS B CB 1 ATOM 5325 N N . LEU B 1 255 ? 3.689 -25.193 10.339 1.00 40.61 ? 255 LEU B N 1 ATOM 5326 C CA . LEU B 1 255 ? 4.966 -25.196 11.066 1.00 39.60 ? 255 LEU B CA 1 ATOM 5327 C C . LEU B 1 255 ? 5.124 -26.509 11.839 1.00 38.54 ? 255 LEU B C 1 ATOM 5328 O O . LEU B 1 255 ? 4.163 -26.972 12.436 1.00 38.48 ? 255 LEU B O 1 ATOM 5329 C CB . LEU B 1 255 ? 5.007 -24.009 12.044 1.00 39.64 ? 255 LEU B CB 1 ATOM 5330 C CG . LEU B 1 255 ? 6.390 -23.474 12.423 1.00 39.02 ? 255 LEU B CG 1 ATOM 5331 C CD1 . LEU B 1 255 ? 7.241 -23.253 11.186 1.00 34.99 ? 255 LEU B CD1 1 ATOM 5332 C CD2 . LEU B 1 255 ? 6.233 -22.205 13.255 1.00 39.03 ? 255 LEU B CD2 1 ATOM 5333 N N . SER B 1 256 ? 6.303 -27.128 11.812 1.00 37.52 ? 256 SER B N 1 ATOM 5334 C CA . SER B 1 256 ? 6.505 -28.381 12.576 1.00 36.68 ? 256 SER B CA 1 ATOM 5335 C C . SER B 1 256 ? 6.062 -28.281 14.045 1.00 35.74 ? 256 SER B C 1 ATOM 5336 O O . SER B 1 256 ? 6.072 -27.185 14.633 1.00 35.56 ? 256 SER B O 1 ATOM 5337 C CB . SER B 1 256 ? 7.952 -28.861 12.534 1.00 36.45 ? 256 SER B CB 1 ATOM 5338 O OG . SER B 1 256 ? 8.092 -30.037 13.337 1.00 35.75 ? 256 SER B OG 1 ATOM 5339 N N . PRO B 1 257 ? 5.639 -29.420 14.645 1.00 35.36 ? 257 PRO B N 1 ATOM 5340 C CA . PRO B 1 257 ? 5.258 -29.332 16.076 1.00 34.33 ? 257 PRO B CA 1 ATOM 5341 C C . PRO B 1 257 ? 6.505 -29.194 17.030 1.00 33.16 ? 257 PRO B C 1 ATOM 5342 O O . PRO B 1 257 ? 6.400 -28.638 18.146 1.00 33.07 ? 257 PRO B O 1 ATOM 5343 C CB . PRO B 1 257 ? 4.466 -30.625 16.310 1.00 34.19 ? 257 PRO B CB 1 ATOM 5344 C CG . PRO B 1 257 ? 4.230 -31.222 14.965 1.00 34.98 ? 257 PRO B CG 1 ATOM 5345 C CD . PRO B 1 257 ? 5.341 -30.751 14.080 1.00 35.46 ? 257 PRO B CD 1 ATOM 5346 N N . PHE B 1 258 ? 7.680 -29.617 16.573 1.00 31.15 ? 258 PHE B N 1 ATOM 5347 C CA . PHE B 1 258 ? 8.897 -29.343 17.310 1.00 29.66 ? 258 PHE B CA 1 ATOM 5348 C C . PHE B 1 258 ? 9.041 -27.865 17.627 1.00 29.80 ? 258 PHE B C 1 ATOM 5349 O O . PHE B 1 258 ? 9.594 -27.498 18.677 1.00 28.76 ? 258 PHE B O 1 ATOM 5350 C CB . PHE B 1 258 ? 10.119 -29.859 16.567 1.00 28.17 ? 258 PHE B CB 1 ATOM 5351 C CG . PHE B 1 258 ? 10.188 -31.365 16.493 1.00 28.07 ? 258 PHE B CG 1 ATOM 5352 C CD1 . PHE B 1 258 ? 10.691 -32.105 17.580 1.00 26.46 ? 258 PHE B CD1 1 ATOM 5353 C CD2 . PHE B 1 258 ? 9.778 -32.054 15.347 1.00 27.38 ? 258 PHE B CD2 1 ATOM 5354 C CE1 . PHE B 1 258 ? 10.776 -33.493 17.538 1.00 27.14 ? 258 PHE B CE1 1 ATOM 5355 C CE2 . PHE B 1 258 ? 9.855 -33.475 15.293 1.00 29.03 ? 258 PHE B CE2 1 ATOM 5356 C CZ . PHE B 1 258 ? 10.364 -34.195 16.393 1.00 28.44 ? 258 PHE B CZ 1 ATOM 5357 N N . CYS B 1 259 ? 8.551 -27.011 16.734 1.00 29.42 ? 259 CYS B N 1 ATOM 5358 C CA . CYS B 1 259 ? 8.839 -25.575 16.817 1.00 30.15 ? 259 CYS B CA 1 ATOM 5359 C C . CYS B 1 259 ? 8.212 -24.921 18.011 1.00 30.83 ? 259 CYS B C 1 ATOM 5360 O O . CYS B 1 259 ? 8.723 -23.929 18.573 1.00 30.99 ? 259 CYS B O 1 ATOM 5361 C CB . CYS B 1 259 ? 8.367 -24.845 15.544 1.00 29.52 ? 259 CYS B CB 1 ATOM 5362 S SG . CYS B 1 259 ? 9.108 -25.568 14.125 1.00 27.09 ? 259 CYS B SG 1 ATOM 5363 N N . ASP B 1 260 ? 7.074 -25.463 18.384 1.00 31.98 ? 260 ASP B N 1 ATOM 5364 C CA . ASP B 1 260 ? 6.280 -24.882 19.459 1.00 32.89 ? 260 ASP B CA 1 ATOM 5365 C C . ASP B 1 260 ? 6.771 -25.376 20.856 1.00 32.15 ? 260 ASP B C 1 ATOM 5366 O O . ASP B 1 260 ? 6.322 -24.892 21.884 1.00 32.12 ? 260 ASP B O 1 ATOM 5367 C CB . ASP B 1 260 ? 4.806 -25.193 19.184 1.00 33.81 ? 260 ASP B CB 1 ATOM 5368 C CG . ASP B 1 260 ? 3.852 -24.258 19.913 1.00 39.19 ? 260 ASP B CG 1 ATOM 5369 O OD1 . ASP B 1 260 ? 4.243 -23.107 20.291 1.00 42.67 ? 260 ASP B OD1 1 ATOM 5370 O OD2 . ASP B 1 260 ? 2.677 -24.689 20.098 1.00 44.71 ? 260 ASP B OD2 1 ATOM 5371 N N . LEU B 1 261 ? 7.731 -26.310 20.884 1.00 30.81 ? 261 LEU B N 1 ATOM 5372 C CA . LEU B 1 261 ? 8.385 -26.659 22.144 1.00 29.59 ? 261 LEU B CA 1 ATOM 5373 C C . LEU B 1 261 ? 9.319 -25.560 22.637 1.00 28.86 ? 261 LEU B C 1 ATOM 5374 O O . LEU B 1 261 ? 9.771 -25.589 23.751 1.00 28.67 ? 261 LEU B O 1 ATOM 5375 C CB . LEU B 1 261 ? 9.117 -27.992 22.044 1.00 28.94 ? 261 LEU B CB 1 ATOM 5376 C CG . LEU B 1 261 ? 8.329 -29.182 21.448 1.00 28.30 ? 261 LEU B CG 1 ATOM 5377 C CD1 . LEU B 1 261 ? 9.236 -30.399 21.294 1.00 27.55 ? 261 LEU B CD1 1 ATOM 5378 C CD2 . LEU B 1 261 ? 7.141 -29.561 22.261 1.00 27.86 ? 261 LEU B CD2 1 ATOM 5379 N N . PHE B 1 262 ? 9.583 -24.567 21.814 1.00 27.65 ? 262 PHE B N 1 ATOM 5380 C CA . PHE B 1 262 ? 10.545 -23.531 22.177 1.00 27.11 ? 262 PHE B CA 1 ATOM 5381 C C . PHE B 1 262 ? 9.922 -22.158 21.985 1.00 26.77 ? 262 PHE B C 1 ATOM 5382 O O . PHE B 1 262 ? 9.088 -21.992 21.134 1.00 25.50 ? 262 PHE B O 1 ATOM 5383 C CB . PHE B 1 262 ? 11.816 -23.696 21.323 1.00 25.62 ? 262 PHE B CB 1 ATOM 5384 C CG . PHE B 1 262 ? 12.315 -25.078 21.318 1.00 25.02 ? 262 PHE B CG 1 ATOM 5385 C CD1 . PHE B 1 262 ? 13.161 -25.522 22.334 1.00 24.20 ? 262 PHE B CD1 1 ATOM 5386 C CD2 . PHE B 1 262 ? 11.899 -25.982 20.360 1.00 20.31 ? 262 PHE B CD2 1 ATOM 5387 C CE1 . PHE B 1 262 ? 13.601 -26.868 22.363 1.00 20.97 ? 262 PHE B CE1 1 ATOM 5388 C CE2 . PHE B 1 262 ? 12.331 -27.303 20.402 1.00 19.64 ? 262 PHE B CE2 1 ATOM 5389 C CZ . PHE B 1 262 ? 13.181 -27.741 21.382 1.00 20.52 ? 262 PHE B CZ 1 ATOM 5390 N N . THR B 1 263 ? 10.351 -21.178 22.771 1.00 27.36 ? 263 THR B N 1 ATOM 5391 C CA . THR B 1 263 ? 9.790 -19.848 22.659 1.00 27.60 ? 263 THR B CA 1 ATOM 5392 C C . THR B 1 263 ? 10.561 -19.037 21.632 1.00 28.49 ? 263 THR B C 1 ATOM 5393 O O . THR B 1 263 ? 11.743 -19.360 21.298 1.00 28.39 ? 263 THR B O 1 ATOM 5394 C CB . THR B 1 263 ? 9.883 -19.093 23.961 1.00 27.73 ? 263 THR B CB 1 ATOM 5395 O OG1 . THR B 1 263 ? 11.267 -18.810 24.254 1.00 29.36 ? 263 THR B OG1 1 ATOM 5396 C CG2 . THR B 1 263 ? 9.236 -19.860 25.122 1.00 28.91 ? 263 THR B CG2 1 ATOM 5397 N N . HIS B 1 264 ? 9.929 -17.935 21.211 1.00 28.50 ? 264 HIS B N 1 ATOM 5398 C CA . HIS B 1 264 ? 10.505 -16.996 20.272 1.00 29.56 ? 264 HIS B CA 1 ATOM 5399 C C . HIS B 1 264 ? 11.901 -16.596 20.710 1.00 30.37 ? 264 HIS B C 1 ATOM 5400 O O . HIS B 1 264 ? 12.824 -16.478 19.880 1.00 30.68 ? 264 HIS B O 1 ATOM 5401 C CB . HIS B 1 264 ? 9.612 -15.755 20.106 1.00 29.90 ? 264 HIS B CB 1 ATOM 5402 C CG . HIS B 1 264 ? 10.148 -14.756 19.129 1.00 29.37 ? 264 HIS B CG 1 ATOM 5403 N ND1 . HIS B 1 264 ? 10.303 -15.033 17.783 1.00 28.73 ? 264 HIS B ND1 1 ATOM 5404 C CD2 . HIS B 1 264 ? 10.582 -13.482 19.302 1.00 30.46 ? 264 HIS B CD2 1 ATOM 5405 C CE1 . HIS B 1 264 ? 10.807 -13.973 17.168 1.00 26.78 ? 264 HIS B CE1 1 ATOM 5406 N NE2 . HIS B 1 264 ? 10.985 -13.016 18.067 1.00 29.16 ? 264 HIS B NE2 1 ATOM 5407 N N . ASP B 1 265 ? 12.046 -16.393 22.020 1.00 29.52 ? 265 ASP B N 1 ATOM 5408 C CA . ASP B 1 265 ? 13.290 -15.931 22.564 1.00 28.88 ? 265 ASP B CA 1 ATOM 5409 C C . ASP B 1 265 ? 14.393 -16.981 22.495 1.00 26.65 ? 265 ASP B C 1 ATOM 5410 O O . ASP B 1 265 ? 15.547 -16.657 22.340 1.00 24.14 ? 265 ASP B O 1 ATOM 5411 C CB . ASP B 1 265 ? 13.090 -15.445 23.991 1.00 30.48 ? 265 ASP B CB 1 ATOM 5412 C CG . ASP B 1 265 ? 13.928 -14.241 24.286 1.00 36.01 ? 265 ASP B CG 1 ATOM 5413 O OD1 . ASP B 1 265 ? 13.490 -13.082 23.952 1.00 41.41 ? 265 ASP B OD1 1 ATOM 5414 O OD2 . ASP B 1 265 ? 15.043 -14.478 24.825 1.00 40.19 ? 265 ASP B OD2 1 ATOM 5415 N N . GLU B 1 266 ? 14.004 -18.233 22.636 1.00 25.98 ? 266 GLU B N 1 ATOM 5416 C CA . GLU B 1 266 ? 14.891 -19.343 22.448 1.00 26.10 ? 266 GLU B CA 1 ATOM 5417 C C . GLU B 1 266 ? 15.303 -19.461 20.984 1.00 26.01 ? 266 GLU B C 1 ATOM 5418 O O . GLU B 1 266 ? 16.509 -19.679 20.688 1.00 25.85 ? 266 GLU B O 1 ATOM 5419 C CB . GLU B 1 266 ? 14.245 -20.617 22.994 1.00 26.27 ? 266 GLU B CB 1 ATOM 5420 C CG . GLU B 1 266 ? 13.947 -20.404 24.475 1.00 28.34 ? 266 GLU B CG 1 ATOM 5421 C CD . GLU B 1 266 ? 13.101 -21.471 25.171 1.00 30.66 ? 266 GLU B CD 1 ATOM 5422 O OE1 . GLU B 1 266 ? 12.567 -22.403 24.536 1.00 29.66 ? 266 GLU B OE1 1 ATOM 5423 O OE2 . GLU B 1 266 ? 12.986 -21.354 26.401 1.00 33.40 ? 266 GLU B OE2 1 ATOM 5424 N N . TRP B 1 267 ? 14.336 -19.251 20.075 1.00 25.16 ? 267 TRP B N 1 ATOM 5425 C CA . TRP B 1 267 ? 14.649 -19.169 18.641 1.00 24.42 ? 267 TRP B CA 1 ATOM 5426 C C . TRP B 1 267 ? 15.684 -18.095 18.327 1.00 24.27 ? 267 TRP B C 1 ATOM 5427 O O . TRP B 1 267 ? 16.629 -18.360 17.571 1.00 24.39 ? 267 TRP B O 1 ATOM 5428 C CB . TRP B 1 267 ? 13.391 -19.093 17.755 1.00 24.27 ? 267 TRP B CB 1 ATOM 5429 C CG . TRP B 1 267 ? 12.724 -20.427 17.755 1.00 20.34 ? 267 TRP B CG 1 ATOM 5430 C CD1 . TRP B 1 267 ? 11.495 -20.721 18.257 1.00 18.28 ? 267 TRP B CD1 1 ATOM 5431 C CD2 . TRP B 1 267 ? 13.276 -21.655 17.268 1.00 18.03 ? 267 TRP B CD2 1 ATOM 5432 N NE1 . TRP B 1 267 ? 11.238 -22.055 18.117 1.00 17.59 ? 267 TRP B NE1 1 ATOM 5433 C CE2 . TRP B 1 267 ? 12.334 -22.657 17.530 1.00 16.93 ? 267 TRP B CE2 1 ATOM 5434 C CE3 . TRP B 1 267 ? 14.504 -22.007 16.657 1.00 16.22 ? 267 TRP B CE3 1 ATOM 5435 C CZ2 . TRP B 1 267 ? 12.544 -23.981 17.180 1.00 17.23 ? 267 TRP B CZ2 1 ATOM 5436 C CZ3 . TRP B 1 267 ? 14.722 -23.322 16.328 1.00 18.69 ? 267 TRP B CZ3 1 ATOM 5437 C CH2 . TRP B 1 267 ? 13.746 -24.305 16.583 1.00 17.82 ? 267 TRP B CH2 1 ATOM 5438 N N . ILE B 1 268 ? 15.547 -16.931 18.948 1.00 23.11 ? 268 ILE B N 1 ATOM 5439 C CA . ILE B 1 268 ? 16.549 -15.889 18.822 1.00 23.57 ? 268 ILE B CA 1 ATOM 5440 C C . ILE B 1 268 ? 17.953 -16.344 19.245 1.00 23.74 ? 268 ILE B C 1 ATOM 5441 O O . ILE B 1 268 ? 18.940 -16.089 18.513 1.00 24.47 ? 268 ILE B O 1 ATOM 5442 C CB . ILE B 1 268 ? 16.135 -14.615 19.607 1.00 24.20 ? 268 ILE B CB 1 ATOM 5443 C CG1 . ILE B 1 268 ? 14.942 -13.980 18.914 1.00 24.56 ? 268 ILE B CG1 1 ATOM 5444 C CG2 . ILE B 1 268 ? 17.255 -13.577 19.671 1.00 23.27 ? 268 ILE B CG2 1 ATOM 5445 C CD1 . ILE B 1 268 ? 14.225 -13.051 19.785 1.00 29.43 ? 268 ILE B CD1 1 ATOM 5446 N N . ASN B 1 269 ? 18.064 -17.033 20.379 1.00 22.43 ? 269 ASN B N 1 ATOM 5447 C CA . ASN B 1 269 ? 19.339 -17.601 20.777 1.00 22.33 ? 269 ASN B CA 1 ATOM 5448 C C . ASN B 1 269 ? 19.812 -18.681 19.811 1.00 21.52 ? 269 ASN B C 1 ATOM 5449 O O . ASN B 1 269 ? 20.991 -18.714 19.474 1.00 22.27 ? 269 ASN B O 1 ATOM 5450 C CB . ASN B 1 269 ? 19.281 -18.141 22.241 1.00 22.73 ? 269 ASN B CB 1 ATOM 5451 C CG . ASN B 1 269 ? 19.390 -17.003 23.283 1.00 25.62 ? 269 ASN B CG 1 ATOM 5452 O OD1 . ASN B 1 269 ? 20.454 -16.395 23.427 1.00 27.00 ? 269 ASN B OD1 1 ATOM 5453 N ND2 . ASN B 1 269 ? 18.302 -16.718 23.989 1.00 27.35 ? 269 ASN B ND2 1 ATOM 5454 N N . TYR B 1 270 ? 18.920 -19.582 19.389 1.00 19.88 ? 270 TYR B N 1 ATOM 5455 C CA . TYR B 1 270 ? 19.292 -20.566 18.337 1.00 19.96 ? 270 TYR B CA 1 ATOM 5456 C C . TYR B 1 270 ? 19.879 -19.901 17.086 1.00 18.66 ? 270 TYR B C 1 ATOM 5457 O O . TYR B 1 270 ? 21.018 -20.189 16.646 1.00 15.94 ? 270 TYR B O 1 ATOM 5458 C CB . TYR B 1 270 ? 18.089 -21.381 17.944 1.00 19.96 ? 270 TYR B CB 1 ATOM 5459 C CG . TYR B 1 270 ? 18.331 -22.520 16.978 1.00 20.09 ? 270 TYR B CG 1 ATOM 5460 C CD1 . TYR B 1 270 ? 18.813 -23.757 17.424 1.00 18.83 ? 270 TYR B CD1 1 ATOM 5461 C CD2 . TYR B 1 270 ? 18.018 -22.376 15.623 1.00 18.37 ? 270 TYR B CD2 1 ATOM 5462 C CE1 . TYR B 1 270 ? 18.999 -24.818 16.529 1.00 17.30 ? 270 TYR B CE1 1 ATOM 5463 C CE2 . TYR B 1 270 ? 18.216 -23.421 14.732 1.00 16.44 ? 270 TYR B CE2 1 ATOM 5464 C CZ . TYR B 1 270 ? 18.669 -24.634 15.182 1.00 17.76 ? 270 TYR B CZ 1 ATOM 5465 O OH . TYR B 1 270 ? 18.844 -25.681 14.285 1.00 17.91 ? 270 TYR B OH 1 ATOM 5466 N N . ASP B 1 271 ? 19.131 -18.937 16.578 1.00 18.94 ? 271 ASP B N 1 ATOM 5467 C CA . ASP B 1 271 ? 19.565 -18.264 15.382 1.00 19.34 ? 271 ASP B CA 1 ATOM 5468 C C . ASP B 1 271 ? 20.936 -17.691 15.644 1.00 19.88 ? 271 ASP B C 1 ATOM 5469 O O . ASP B 1 271 ? 21.831 -17.882 14.849 1.00 21.15 ? 271 ASP B O 1 ATOM 5470 C CB . ASP B 1 271 ? 18.562 -17.190 14.968 1.00 20.56 ? 271 ASP B CB 1 ATOM 5471 C CG . ASP B 1 271 ? 19.039 -16.408 13.769 1.00 20.43 ? 271 ASP B CG 1 ATOM 5472 O OD1 . ASP B 1 271 ? 19.065 -16.981 12.655 1.00 19.39 ? 271 ASP B OD1 1 ATOM 5473 O OD2 . ASP B 1 271 ? 19.437 -15.245 13.954 1.00 22.08 ? 271 ASP B OD2 1 ATOM 5474 N N . TYR B 1 272 ? 21.139 -17.020 16.778 1.00 19.53 ? 272 TYR B N 1 ATOM 5475 C CA . TYR B 1 272 ? 22.441 -16.431 17.030 1.00 18.92 ? 272 TYR B CA 1 ATOM 5476 C C . TYR B 1 272 ? 23.520 -17.463 17.190 1.00 19.58 ? 272 TYR B C 1 ATOM 5477 O O . TYR B 1 272 ? 24.635 -17.290 16.695 1.00 19.72 ? 272 TYR B O 1 ATOM 5478 C CB . TYR B 1 272 ? 22.389 -15.504 18.242 1.00 19.52 ? 272 TYR B CB 1 ATOM 5479 C CG . TYR B 1 272 ? 23.632 -14.678 18.413 1.00 20.92 ? 272 TYR B CG 1 ATOM 5480 C CD1 . TYR B 1 272 ? 23.916 -13.600 17.559 1.00 17.63 ? 272 TYR B CD1 1 ATOM 5481 C CD2 . TYR B 1 272 ? 24.523 -14.958 19.452 1.00 20.05 ? 272 TYR B CD2 1 ATOM 5482 C CE1 . TYR B 1 272 ? 25.078 -12.859 17.745 1.00 20.64 ? 272 TYR B CE1 1 ATOM 5483 C CE2 . TYR B 1 272 ? 25.686 -14.191 19.651 1.00 21.42 ? 272 TYR B CE2 1 ATOM 5484 C CZ . TYR B 1 272 ? 25.954 -13.144 18.811 1.00 21.19 ? 272 TYR B CZ 1 ATOM 5485 O OH . TYR B 1 272 ? 27.119 -12.406 19.045 1.00 20.48 ? 272 TYR B OH 1 ATOM 5486 N N . LEU B 1 273 ? 23.205 -18.573 17.866 1.00 19.22 ? 273 LEU B N 1 ATOM 5487 C CA . LEU B 1 273 ? 24.149 -19.693 17.884 1.00 18.75 ? 273 LEU B CA 1 ATOM 5488 C C . LEU B 1 273 ? 24.629 -20.030 16.471 1.00 18.95 ? 273 LEU B C 1 ATOM 5489 O O . LEU B 1 273 ? 25.831 -20.242 16.230 1.00 17.75 ? 273 LEU B O 1 ATOM 5490 C CB . LEU B 1 273 ? 23.538 -20.934 18.504 1.00 17.46 ? 273 LEU B CB 1 ATOM 5491 C CG . LEU B 1 273 ? 24.375 -22.209 18.545 1.00 21.22 ? 273 LEU B CG 1 ATOM 5492 C CD1 . LEU B 1 273 ? 25.681 -22.005 19.332 1.00 18.68 ? 273 LEU B CD1 1 ATOM 5493 C CD2 . LEU B 1 273 ? 23.553 -23.316 19.202 1.00 21.42 ? 273 LEU B CD2 1 ATOM 5494 N N . GLN B 1 274 ? 23.666 -20.123 15.548 1.00 19.33 ? 274 GLN B N 1 ATOM 5495 C CA . GLN B 1 274 ? 23.959 -20.451 14.146 1.00 19.54 ? 274 GLN B CA 1 ATOM 5496 C C . GLN B 1 274 ? 24.926 -19.428 13.501 1.00 19.22 ? 274 GLN B C 1 ATOM 5497 O O . GLN B 1 274 ? 25.904 -19.819 12.866 1.00 19.91 ? 274 GLN B O 1 ATOM 5498 C CB . GLN B 1 274 ? 22.665 -20.627 13.318 1.00 19.41 ? 274 GLN B CB 1 ATOM 5499 C CG . GLN B 1 274 ? 21.705 -21.764 13.730 1.00 16.74 ? 274 GLN B CG 1 ATOM 5500 C CD . GLN B 1 274 ? 22.319 -23.025 14.318 1.00 21.33 ? 274 GLN B CD 1 ATOM 5501 O OE1 . GLN B 1 274 ? 23.265 -23.604 13.784 1.00 22.75 ? 274 GLN B OE1 1 ATOM 5502 N NE2 . GLN B 1 274 ? 21.711 -23.516 15.412 1.00 24.12 ? 274 GLN B NE2 1 ATOM 5503 N N . SER B 1 275 ? 24.693 -18.126 13.720 1.00 18.77 ? 275 SER B N 1 ATOM 5504 C CA . SER B 1 275 ? 25.604 -17.112 13.231 1.00 17.64 ? 275 SER B CA 1 ATOM 5505 C C . SER B 1 275 ? 26.977 -17.302 13.833 1.00 18.81 ? 275 SER B C 1 ATOM 5506 O O . SER B 1 275 ? 27.989 -17.079 13.141 1.00 17.05 ? 275 SER B O 1 ATOM 5507 C CB . SER B 1 275 ? 25.097 -15.709 13.540 1.00 17.75 ? 275 SER B CB 1 ATOM 5508 O OG . SER B 1 275 ? 23.773 -15.511 13.051 1.00 16.03 ? 275 SER B OG 1 ATOM 5509 N N . LEU B 1 276 ? 27.033 -17.678 15.130 1.00 19.47 ? 276 LEU B N 1 ATOM 5510 C CA . LEU B 1 276 ? 28.351 -17.923 15.814 1.00 19.92 ? 276 LEU B CA 1 ATOM 5511 C C . LEU B 1 276 ? 29.146 -19.067 15.193 1.00 20.42 ? 276 LEU B C 1 ATOM 5512 O O . LEU B 1 276 ? 30.365 -18.920 14.901 1.00 20.62 ? 276 LEU B O 1 ATOM 5513 C CB . LEU B 1 276 ? 28.210 -18.167 17.316 1.00 19.53 ? 276 LEU B CB 1 ATOM 5514 C CG . LEU B 1 276 ? 27.851 -16.986 18.191 1.00 20.40 ? 276 LEU B CG 1 ATOM 5515 C CD1 . LEU B 1 276 ? 27.486 -17.573 19.557 1.00 18.56 ? 276 LEU B CD1 1 ATOM 5516 C CD2 . LEU B 1 276 ? 29.007 -16.008 18.343 1.00 21.12 ? 276 LEU B CD2 1 ATOM 5517 N N . LYS B 1 277 ? 28.475 -20.195 14.974 1.00 19.84 ? 277 LYS B N 1 ATOM 5518 C CA . LYS B 1 277 ? 29.116 -21.316 14.340 1.00 20.40 ? 277 LYS B CA 1 ATOM 5519 C C . LYS B 1 277 ? 29.787 -20.904 13.001 1.00 20.39 ? 277 LYS B C 1 ATOM 5520 O O . LYS B 1 277 ? 30.952 -21.249 12.724 1.00 19.05 ? 277 LYS B O 1 ATOM 5521 C CB . LYS B 1 277 ? 28.085 -22.404 14.059 1.00 21.23 ? 277 LYS B CB 1 ATOM 5522 C CG . LYS B 1 277 ? 27.448 -23.138 15.292 1.00 22.83 ? 277 LYS B CG 1 ATOM 5523 C CD . LYS B 1 277 ? 27.057 -24.559 14.825 1.00 27.80 ? 277 LYS B CD 1 ATOM 5524 C CE . LYS B 1 277 ? 25.636 -24.870 15.171 1.00 33.02 ? 277 LYS B CE 1 ATOM 5525 N NZ . LYS B 1 277 ? 25.195 -26.252 14.679 1.00 34.11 ? 277 LYS B NZ 1 ATOM 5526 N N . LYS B 1 278 ? 29.029 -20.165 12.174 1.00 19.76 ? 278 LYS B N 1 ATOM 5527 C CA . LYS B 1 278 ? 29.528 -19.765 10.854 1.00 19.40 ? 278 LYS B CA 1 ATOM 5528 C C . LYS B 1 278 ? 30.622 -18.717 11.011 1.00 19.58 ? 278 LYS B C 1 ATOM 5529 O O . LYS B 1 278 ? 31.723 -18.903 10.427 1.00 19.43 ? 278 LYS B O 1 ATOM 5530 C CB . LYS B 1 278 ? 28.391 -19.316 9.929 1.00 18.64 ? 278 LYS B CB 1 ATOM 5531 C CG . LYS B 1 278 ? 27.398 -20.496 9.632 1.00 20.32 ? 278 LYS B CG 1 ATOM 5532 C CD . LYS B 1 278 ? 28.150 -21.763 9.259 1.00 15.44 ? 278 LYS B CD 1 ATOM 5533 C CE . LYS B 1 278 ? 27.173 -22.866 8.897 1.00 21.23 ? 278 LYS B CE 1 ATOM 5534 N NZ . LYS B 1 278 ? 27.827 -24.222 8.878 1.00 16.16 ? 278 LYS B NZ 1 ATOM 5535 N N . TYR B 1 279 ? 30.357 -17.661 11.817 1.00 17.47 ? 279 TYR B N 1 ATOM 5536 C CA . TYR B 1 279 ? 31.353 -16.605 12.038 1.00 17.59 ? 279 TYR B CA 1 ATOM 5537 C C . TYR B 1 279 ? 32.702 -17.059 12.527 1.00 18.00 ? 279 TYR B C 1 ATOM 5538 O O . TYR B 1 279 ? 33.748 -16.658 11.970 1.00 17.23 ? 279 TYR B O 1 ATOM 5539 C CB . TYR B 1 279 ? 30.833 -15.546 12.995 1.00 19.04 ? 279 TYR B CB 1 ATOM 5540 C CG . TYR B 1 279 ? 31.712 -14.333 13.044 1.00 19.44 ? 279 TYR B CG 1 ATOM 5541 C CD1 . TYR B 1 279 ? 31.597 -13.313 12.063 1.00 17.10 ? 279 TYR B CD1 1 ATOM 5542 C CD2 . TYR B 1 279 ? 32.700 -14.219 14.012 1.00 19.23 ? 279 TYR B CD2 1 ATOM 5543 C CE1 . TYR B 1 279 ? 32.456 -12.193 12.052 1.00 17.91 ? 279 TYR B CE1 1 ATOM 5544 C CE2 . TYR B 1 279 ? 33.554 -13.070 14.040 1.00 21.47 ? 279 TYR B CE2 1 ATOM 5545 C CZ . TYR B 1 279 ? 33.428 -12.072 13.072 1.00 22.27 ? 279 TYR B CZ 1 ATOM 5546 O OH . TYR B 1 279 ? 34.262 -10.967 13.135 1.00 20.93 ? 279 TYR B OH 1 ATOM 5547 N N . TYR B 1 280 ? 32.701 -17.898 13.578 1.00 18.41 ? 280 TYR B N 1 ATOM 5548 C CA . TYR B 1 280 ? 33.957 -18.480 14.116 1.00 17.39 ? 280 TYR B CA 1 ATOM 5549 C C . TYR B 1 280 ? 34.428 -19.742 13.389 1.00 17.86 ? 280 TYR B C 1 ATOM 5550 O O . TYR B 1 280 ? 35.566 -20.140 13.541 1.00 18.83 ? 280 TYR B O 1 ATOM 5551 C CB . TYR B 1 280 ? 33.850 -18.703 15.648 1.00 16.47 ? 280 TYR B CB 1 ATOM 5552 C CG . TYR B 1 280 ? 33.826 -17.367 16.354 1.00 17.34 ? 280 TYR B CG 1 ATOM 5553 C CD1 . TYR B 1 280 ? 34.977 -16.589 16.444 1.00 16.35 ? 280 TYR B CD1 1 ATOM 5554 C CD2 . TYR B 1 280 ? 32.646 -16.837 16.851 1.00 14.41 ? 280 TYR B CD2 1 ATOM 5555 C CE1 . TYR B 1 280 ? 34.932 -15.300 17.031 1.00 18.84 ? 280 TYR B CE1 1 ATOM 5556 C CE2 . TYR B 1 280 ? 32.592 -15.547 17.456 1.00 14.17 ? 280 TYR B CE2 1 ATOM 5557 C CZ . TYR B 1 280 ? 33.743 -14.793 17.557 1.00 16.09 ? 280 TYR B CZ 1 ATOM 5558 O OH . TYR B 1 280 ? 33.729 -13.505 18.101 1.00 14.78 ? 280 TYR B OH 1 ATOM 5559 N N . GLY B 1 281 ? 33.536 -20.422 12.678 1.00 17.63 ? 281 GLY B N 1 ATOM 5560 C CA . GLY B 1 281 ? 33.926 -21.576 11.865 1.00 17.32 ? 281 GLY B CA 1 ATOM 5561 C C . GLY B 1 281 ? 34.630 -21.196 10.570 1.00 18.09 ? 281 GLY B C 1 ATOM 5562 O O . GLY B 1 281 ? 35.730 -21.665 10.319 1.00 18.49 ? 281 GLY B O 1 ATOM 5563 N N . HIS B 1 282 ? 34.022 -20.309 9.777 1.00 18.38 ? 282 HIS B N 1 ATOM 5564 C CA . HIS B 1 282 ? 34.459 -20.022 8.412 1.00 19.36 ? 282 HIS B CA 1 ATOM 5565 C C . HIS B 1 282 ? 34.551 -18.543 8.062 1.00 18.39 ? 282 HIS B C 1 ATOM 5566 O O . HIS B 1 282 ? 35.165 -18.197 7.087 1.00 18.60 ? 282 HIS B O 1 ATOM 5567 C CB . HIS B 1 282 ? 33.532 -20.732 7.422 1.00 20.20 ? 282 HIS B CB 1 ATOM 5568 C CG . HIS B 1 282 ? 33.556 -22.219 7.560 1.00 20.53 ? 282 HIS B CG 1 ATOM 5569 N ND1 . HIS B 1 282 ? 34.372 -23.020 6.785 1.00 21.22 ? 282 HIS B ND1 1 ATOM 5570 C CD2 . HIS B 1 282 ? 32.877 -23.047 8.401 1.00 22.56 ? 282 HIS B CD2 1 ATOM 5571 C CE1 . HIS B 1 282 ? 34.232 -24.274 7.174 1.00 23.63 ? 282 HIS B CE1 1 ATOM 5572 N NE2 . HIS B 1 282 ? 33.323 -24.321 8.149 1.00 24.55 ? 282 HIS B NE2 1 ATOM 5573 N N . GLY B 1 283 ? 33.961 -17.687 8.878 1.00 18.43 ? 283 GLY B N 1 ATOM 5574 C CA . GLY B 1 283 ? 34.118 -16.213 8.733 1.00 18.04 ? 283 GLY B CA 1 ATOM 5575 C C . GLY B 1 283 ? 35.294 -15.551 9.402 1.00 17.86 ? 283 GLY B C 1 ATOM 5576 O O . GLY B 1 283 ? 36.251 -16.214 9.814 1.00 18.81 ? 283 GLY B O 1 ATOM 5577 N N . ALA B 1 284 ? 35.229 -14.217 9.491 1.00 18.40 ? 284 ALA B N 1 ATOM 5578 C CA . ALA B 1 284 ? 36.307 -13.364 10.078 1.00 19.52 ? 284 ALA B CA 1 ATOM 5579 C C . ALA B 1 284 ? 36.779 -13.801 11.476 1.00 19.87 ? 284 ALA B C 1 ATOM 5580 O O . ALA B 1 284 ? 37.958 -13.690 11.803 1.00 20.90 ? 284 ALA B O 1 ATOM 5581 C CB . ALA B 1 284 ? 35.891 -11.882 10.098 1.00 18.49 ? 284 ALA B CB 1 ATOM 5582 N N . GLY B 1 285 ? 35.852 -14.308 12.283 1.00 19.43 ? 285 GLY B N 1 ATOM 5583 C CA . GLY B 1 285 ? 36.200 -14.893 13.532 1.00 19.06 ? 285 GLY B CA 1 ATOM 5584 C C . GLY B 1 285 ? 37.167 -16.048 13.551 1.00 20.01 ? 285 GLY B C 1 ATOM 5585 O O . GLY B 1 285 ? 37.805 -16.254 14.585 1.00 19.59 ? 285 GLY B O 1 ATOM 5586 N N . ASN B 1 286 ? 37.262 -16.833 12.471 1.00 18.73 ? 286 ASN B N 1 ATOM 5587 C CA . ASN B 1 286 ? 38.298 -17.830 12.437 1.00 19.13 ? 286 ASN B CA 1 ATOM 5588 C C . ASN B 1 286 ? 39.575 -17.321 11.782 1.00 19.62 ? 286 ASN B C 1 ATOM 5589 O O . ASN B 1 286 ? 39.551 -16.706 10.756 1.00 18.97 ? 286 ASN B O 1 ATOM 5590 C CB . ASN B 1 286 ? 37.799 -19.063 11.724 1.00 19.69 ? 286 ASN B CB 1 ATOM 5591 C CG . ASN B 1 286 ? 38.705 -20.180 11.870 1.00 21.06 ? 286 ASN B CG 1 ATOM 5592 O OD1 . ASN B 1 286 ? 39.812 -20.202 11.281 1.00 22.92 ? 286 ASN B OD1 1 ATOM 5593 N ND2 . ASN B 1 286 ? 38.300 -21.132 12.685 1.00 18.58 ? 286 ASN B ND2 1 ATOM 5594 N N . PRO B 1 287 ? 40.733 -17.574 12.385 1.00 21.24 ? 287 PRO B N 1 ATOM 5595 C CA . PRO B 1 287 ? 41.902 -16.910 11.768 1.00 21.11 ? 287 PRO B CA 1 ATOM 5596 C C . PRO B 1 287 ? 42.159 -17.288 10.311 1.00 21.00 ? 287 PRO B C 1 ATOM 5597 O O . PRO B 1 287 ? 42.777 -16.514 9.594 1.00 19.91 ? 287 PRO B O 1 ATOM 5598 C CB . PRO B 1 287 ? 43.083 -17.336 12.656 1.00 21.70 ? 287 PRO B CB 1 ATOM 5599 C CG . PRO B 1 287 ? 42.552 -18.478 13.561 1.00 23.06 ? 287 PRO B CG 1 ATOM 5600 C CD . PRO B 1 287 ? 41.059 -18.307 13.633 1.00 21.71 ? 287 PRO B CD 1 ATOM 5601 N N . LEU B 1 288 ? 41.662 -18.452 9.872 1.00 21.36 ? 288 LEU B N 1 ATOM 5602 C CA . LEU B 1 288 ? 41.930 -18.928 8.511 1.00 20.92 ? 288 LEU B CA 1 ATOM 5603 C C . LEU B 1 288 ? 40.660 -19.016 7.681 1.00 20.41 ? 288 LEU B C 1 ATOM 5604 O O . LEU B 1 288 ? 40.629 -19.641 6.604 1.00 20.74 ? 288 LEU B O 1 ATOM 5605 C CB . LEU B 1 288 ? 42.643 -20.274 8.586 1.00 20.92 ? 288 LEU B CB 1 ATOM 5606 C CG . LEU B 1 288 ? 44.121 -20.233 9.039 1.00 22.69 ? 288 LEU B CG 1 ATOM 5607 C CD1 . LEU B 1 288 ? 44.648 -21.656 9.079 1.00 22.54 ? 288 LEU B CD1 1 ATOM 5608 C CD2 . LEU B 1 288 ? 45.034 -19.398 8.144 1.00 25.95 ? 288 LEU B CD2 1 ATOM 5609 N N . GLY B 1 289 ? 39.587 -18.453 8.221 1.00 19.29 ? 289 GLY B N 1 ATOM 5610 C CA . GLY B 1 289 ? 38.256 -18.509 7.609 1.00 18.84 ? 289 GLY B CA 1 ATOM 5611 C C . GLY B 1 289 ? 38.295 -17.744 6.281 1.00 18.01 ? 289 GLY B C 1 ATOM 5612 O O . GLY B 1 289 ? 38.257 -18.360 5.190 1.00 17.85 ? 289 GLY B O 1 ATOM 5613 N N . PRO B 1 290 ? 38.469 -16.426 6.362 1.00 16.98 ? 290 PRO B N 1 ATOM 5614 C CA . PRO B 1 290 ? 38.423 -15.612 5.128 1.00 17.57 ? 290 PRO B CA 1 ATOM 5615 C C . PRO B 1 290 ? 39.448 -16.099 4.123 1.00 18.23 ? 290 PRO B C 1 ATOM 5616 O O . PRO B 1 290 ? 39.257 -15.937 2.886 1.00 18.98 ? 290 PRO B O 1 ATOM 5617 C CB . PRO B 1 290 ? 38.793 -14.179 5.618 1.00 16.39 ? 290 PRO B CB 1 ATOM 5618 C CG . PRO B 1 290 ? 38.328 -14.221 7.099 1.00 16.08 ? 290 PRO B CG 1 ATOM 5619 C CD . PRO B 1 290 ? 38.831 -15.601 7.536 1.00 16.53 ? 290 PRO B CD 1 ATOM 5620 N N . THR B 1 291 ? 40.513 -16.712 4.644 1.00 18.03 ? 291 THR B N 1 ATOM 5621 C CA . THR B 1 291 ? 41.550 -17.273 3.782 1.00 18.55 ? 291 THR B CA 1 ATOM 5622 C C . THR B 1 291 ? 41.003 -18.423 2.864 1.00 18.47 ? 291 THR B C 1 ATOM 5623 O O . THR B 1 291 ? 41.515 -18.636 1.757 1.00 19.54 ? 291 THR B O 1 ATOM 5624 C CB . THR B 1 291 ? 42.787 -17.673 4.584 1.00 17.65 ? 291 THR B CB 1 ATOM 5625 O OG1 . THR B 1 291 ? 43.605 -16.514 4.813 1.00 17.83 ? 291 THR B OG1 1 ATOM 5626 C CG2 . THR B 1 291 ? 43.578 -18.750 3.887 1.00 16.92 ? 291 THR B CG2 1 ATOM 5627 N N . GLN B 1 292 ? 39.981 -19.117 3.312 1.00 17.42 ? 292 GLN B N 1 ATOM 5628 C CA . GLN B 1 292 ? 39.314 -20.149 2.514 1.00 18.51 ? 292 GLN B CA 1 ATOM 5629 C C . GLN B 1 292 ? 38.546 -19.543 1.293 1.00 18.51 ? 292 GLN B C 1 ATOM 5630 O O . GLN B 1 292 ? 38.148 -20.260 0.379 1.00 19.10 ? 292 GLN B O 1 ATOM 5631 C CB . GLN B 1 292 ? 38.316 -20.941 3.398 1.00 18.52 ? 292 GLN B CB 1 ATOM 5632 C CG . GLN B 1 292 ? 38.979 -21.616 4.615 1.00 17.87 ? 292 GLN B CG 1 ATOM 5633 C CD . GLN B 1 292 ? 40.323 -22.298 4.266 1.00 19.01 ? 292 GLN B CD 1 ATOM 5634 O OE1 . GLN B 1 292 ? 40.345 -23.327 3.564 1.00 22.11 ? 292 GLN B OE1 1 ATOM 5635 N NE2 . GLN B 1 292 ? 41.429 -21.762 4.778 1.00 13.49 ? 292 GLN B NE2 1 ATOM 5636 N N . GLY B 1 293 ? 38.332 -18.226 1.287 1.00 18.51 ? 293 GLY B N 1 ATOM 5637 C CA . GLY B 1 293 ? 37.570 -17.580 0.204 1.00 17.53 ? 293 GLY B CA 1 ATOM 5638 C C . GLY B 1 293 ? 38.452 -16.906 -0.822 1.00 17.41 ? 293 GLY B C 1 ATOM 5639 O O . GLY B 1 293 ? 37.953 -16.292 -1.760 1.00 16.93 ? 293 GLY B O 1 ATOM 5640 N N . VAL B 1 294 ? 39.764 -16.988 -0.649 1.00 17.16 ? 294 VAL B N 1 ATOM 5641 C CA . VAL B 1 294 ? 40.576 -16.168 -1.497 1.00 18.61 ? 294 VAL B CA 1 ATOM 5642 C C . VAL B 1 294 ? 40.683 -16.691 -2.935 1.00 17.28 ? 294 VAL B C 1 ATOM 5643 O O . VAL B 1 294 ? 40.730 -15.896 -3.849 1.00 19.09 ? 294 VAL B O 1 ATOM 5644 C CB . VAL B 1 294 ? 41.976 -15.710 -0.903 1.00 19.08 ? 294 VAL B CB 1 ATOM 5645 C CG1 . VAL B 1 294 ? 41.996 -15.550 0.655 1.00 20.88 ? 294 VAL B CG1 1 ATOM 5646 C CG2 . VAL B 1 294 ? 43.078 -16.467 -1.469 1.00 19.72 ? 294 VAL B CG2 1 ATOM 5647 N N . GLY B 1 295 ? 40.683 -18.014 -3.106 1.00 17.02 ? 295 GLY B N 1 ATOM 5648 C CA . GLY B 1 295 ? 40.649 -18.664 -4.405 1.00 16.31 ? 295 GLY B CA 1 ATOM 5649 C C . GLY B 1 295 ? 39.493 -18.149 -5.245 1.00 16.23 ? 295 GLY B C 1 ATOM 5650 O O . GLY B 1 295 ? 39.705 -17.721 -6.360 1.00 17.18 ? 295 GLY B O 1 ATOM 5651 N N . TYR B 1 296 ? 38.283 -18.163 -4.705 1.00 14.79 ? 296 TYR B N 1 ATOM 5652 C CA . TYR B 1 296 ? 37.165 -17.731 -5.431 1.00 15.21 ? 296 TYR B CA 1 ATOM 5653 C C . TYR B 1 296 ? 37.190 -16.220 -5.702 1.00 16.61 ? 296 TYR B C 1 ATOM 5654 O O . TYR B 1 296 ? 36.753 -15.774 -6.773 1.00 17.34 ? 296 TYR B O 1 ATOM 5655 C CB . TYR B 1 296 ? 35.903 -18.104 -4.650 1.00 16.30 ? 296 TYR B CB 1 ATOM 5656 C CG . TYR B 1 296 ? 34.648 -17.940 -5.462 1.00 16.87 ? 296 TYR B CG 1 ATOM 5657 C CD1 . TYR B 1 296 ? 34.187 -18.988 -6.237 1.00 19.26 ? 296 TYR B CD1 1 ATOM 5658 C CD2 . TYR B 1 296 ? 33.951 -16.719 -5.495 1.00 17.86 ? 296 TYR B CD2 1 ATOM 5659 C CE1 . TYR B 1 296 ? 33.014 -18.844 -7.003 1.00 21.35 ? 296 TYR B CE1 1 ATOM 5660 C CE2 . TYR B 1 296 ? 32.787 -16.562 -6.256 1.00 19.61 ? 296 TYR B CE2 1 ATOM 5661 C CZ . TYR B 1 296 ? 32.334 -17.625 -7.025 1.00 20.16 ? 296 TYR B CZ 1 ATOM 5662 O OH . TYR B 1 296 ? 31.180 -17.508 -7.789 1.00 21.87 ? 296 TYR B OH 1 ATOM 5663 N N . ALA B 1 297 ? 37.653 -15.432 -4.724 1.00 15.63 ? 297 ALA B N 1 ATOM 5664 C CA . ALA B 1 297 ? 37.811 -14.040 -4.884 1.00 15.16 ? 297 ALA B CA 1 ATOM 5665 C C . ALA B 1 297 ? 38.815 -13.763 -6.019 1.00 15.70 ? 297 ALA B C 1 ATOM 5666 O O . ALA B 1 297 ? 38.629 -12.844 -6.834 1.00 15.23 ? 297 ALA B O 1 ATOM 5667 C CB . ALA B 1 297 ? 38.301 -13.404 -3.522 1.00 15.08 ? 297 ALA B CB 1 ATOM 5668 N N . ASN B 1 298 ? 39.881 -14.526 -6.089 1.00 14.82 ? 298 ASN B N 1 ATOM 5669 C CA . ASN B 1 298 ? 40.785 -14.262 -7.180 1.00 17.14 ? 298 ASN B CA 1 ATOM 5670 C C . ASN B 1 298 ? 40.198 -14.677 -8.536 1.00 18.29 ? 298 ASN B C 1 ATOM 5671 O O . ASN B 1 298 ? 40.485 -14.038 -9.564 1.00 19.78 ? 298 ASN B O 1 ATOM 5672 C CB . ASN B 1 298 ? 42.137 -14.932 -6.946 1.00 17.10 ? 298 ASN B CB 1 ATOM 5673 C CG . ASN B 1 298 ? 42.972 -14.171 -5.941 1.00 18.22 ? 298 ASN B CG 1 ATOM 5674 O OD1 . ASN B 1 298 ? 42.941 -12.955 -5.921 1.00 13.42 ? 298 ASN B OD1 1 ATOM 5675 N ND2 . ASN B 1 298 ? 43.693 -14.892 -5.087 1.00 16.53 ? 298 ASN B ND2 1 ATOM 5676 N N . GLU B 1 299 ? 39.360 -15.719 -8.547 1.00 17.70 ? 299 GLU B N 1 ATOM 5677 C CA . GLU B 1 299 ? 38.566 -16.054 -9.774 1.00 16.71 ? 299 GLU B CA 1 ATOM 5678 C C . GLU B 1 299 ? 37.593 -14.946 -10.114 1.00 16.92 ? 299 GLU B C 1 ATOM 5679 O O . GLU B 1 299 ? 37.509 -14.511 -11.274 1.00 17.55 ? 299 GLU B O 1 ATOM 5680 C CB . GLU B 1 299 ? 37.833 -17.391 -9.630 1.00 16.34 ? 299 GLU B CB 1 ATOM 5681 C CG . GLU B 1 299 ? 38.826 -18.553 -9.576 1.00 13.15 ? 299 GLU B CG 1 ATOM 5682 C CD . GLU B 1 299 ? 38.142 -19.856 -9.397 1.00 17.09 ? 299 GLU B CD 1 ATOM 5683 O OE1 . GLU B 1 299 ? 36.990 -19.925 -8.831 1.00 13.12 ? 299 GLU B OE1 1 ATOM 5684 O OE2 . GLU B 1 299 ? 38.739 -20.831 -9.852 1.00 18.52 ? 299 GLU B OE2 1 ATOM 5685 N N . LEU B 1 300 ? 36.882 -14.443 -9.106 1.00 16.69 ? 300 LEU B N 1 ATOM 5686 C CA . LEU B 1 300 ? 36.005 -13.320 -9.345 1.00 17.43 ? 300 LEU B CA 1 ATOM 5687 C C . LEU B 1 300 ? 36.743 -12.114 -9.961 1.00 18.06 ? 300 LEU B C 1 ATOM 5688 O O . LEU B 1 300 ? 36.203 -11.474 -10.839 1.00 19.57 ? 300 LEU B O 1 ATOM 5689 C CB . LEU B 1 300 ? 35.311 -12.869 -8.087 1.00 16.54 ? 300 LEU B CB 1 ATOM 5690 C CG . LEU B 1 300 ? 34.442 -11.650 -8.374 1.00 16.49 ? 300 LEU B CG 1 ATOM 5691 C CD1 . LEU B 1 300 ? 33.335 -12.067 -9.365 1.00 16.37 ? 300 LEU B CD1 1 ATOM 5692 C CD2 . LEU B 1 300 ? 33.822 -11.137 -7.071 1.00 16.05 ? 300 LEU B CD2 1 ATOM 5693 N N . ILE B 1 301 ? 37.966 -11.843 -9.525 1.00 18.18 ? 301 ILE B N 1 ATOM 5694 C CA . ILE B 1 301 ? 38.738 -10.710 -10.016 1.00 18.47 ? 301 ILE B CA 1 ATOM 5695 C C . ILE B 1 301 ? 39.132 -10.887 -11.494 1.00 18.77 ? 301 ILE B C 1 ATOM 5696 O O . ILE B 1 301 ? 39.080 -9.929 -12.286 1.00 19.83 ? 301 ILE B O 1 ATOM 5697 C CB . ILE B 1 301 ? 39.992 -10.452 -9.097 1.00 18.42 ? 301 ILE B CB 1 ATOM 5698 C CG1 . ILE B 1 301 ? 39.614 -9.689 -7.804 1.00 19.52 ? 301 ILE B CG1 1 ATOM 5699 C CG2 . ILE B 1 301 ? 41.128 -9.731 -9.852 1.00 18.30 ? 301 ILE B CG2 1 ATOM 5700 C CD1 . ILE B 1 301 ? 40.684 -9.868 -6.699 1.00 16.44 ? 301 ILE B CD1 1 ATOM 5701 N N . ALA B 1 302 ? 39.584 -12.078 -11.848 1.00 18.80 ? 302 ALA B N 1 ATOM 5702 C CA . ALA B 1 302 ? 39.841 -12.463 -13.262 1.00 18.99 ? 302 ALA B CA 1 ATOM 5703 C C . ALA B 1 302 ? 38.616 -12.192 -14.181 1.00 19.92 ? 302 ALA B C 1 ATOM 5704 O O . ALA B 1 302 ? 38.733 -11.581 -15.255 1.00 20.31 ? 302 ALA B O 1 ATOM 5705 C CB . ALA B 1 302 ? 40.214 -13.938 -13.332 1.00 18.04 ? 302 ALA B CB 1 ATOM 5706 N N . ARG B 1 303 ? 37.457 -12.615 -13.709 1.00 19.69 ? 303 ARG B N 1 ATOM 5707 C CA . ARG B 1 303 ? 36.204 -12.391 -14.380 1.00 19.87 ? 303 ARG B CA 1 ATOM 5708 C C . ARG B 1 303 ? 35.826 -10.927 -14.582 1.00 20.77 ? 303 ARG B C 1 ATOM 5709 O O . ARG B 1 303 ? 35.363 -10.559 -15.661 1.00 20.57 ? 303 ARG B O 1 ATOM 5710 C CB . ARG B 1 303 ? 35.085 -13.149 -13.675 1.00 18.04 ? 303 ARG B CB 1 ATOM 5711 C CG . ARG B 1 303 ? 35.220 -14.621 -13.911 1.00 17.85 ? 303 ARG B CG 1 ATOM 5712 C CD . ARG B 1 303 ? 34.162 -15.470 -13.221 1.00 17.25 ? 303 ARG B CD 1 ATOM 5713 N NE . ARG B 1 303 ? 34.267 -16.893 -13.652 1.00 17.61 ? 303 ARG B NE 1 ATOM 5714 C CZ . ARG B 1 303 ? 33.618 -17.898 -13.058 1.00 16.48 ? 303 ARG B CZ 1 ATOM 5715 N NH1 . ARG B 1 303 ? 32.829 -17.625 -12.006 1.00 14.31 ? 303 ARG B NH1 1 ATOM 5716 N NH2 . ARG B 1 303 ? 33.683 -19.150 -13.553 1.00 12.39 ? 303 ARG B NH2 1 ATOM 5717 N N . LEU B 1 304 ? 36.016 -10.111 -13.542 1.00 21.81 ? 304 LEU B N 1 ATOM 5718 C CA . LEU B 1 304 ? 35.662 -8.724 -13.569 1.00 21.41 ? 304 LEU B CA 1 ATOM 5719 C C . LEU B 1 304 ? 36.656 -7.999 -14.475 1.00 22.35 ? 304 LEU B C 1 ATOM 5720 O O . LEU B 1 304 ? 36.271 -7.101 -15.218 1.00 23.02 ? 304 LEU B O 1 ATOM 5721 C CB . LEU B 1 304 ? 35.703 -8.144 -12.167 1.00 21.37 ? 304 LEU B CB 1 ATOM 5722 C CG . LEU B 1 304 ? 34.675 -8.604 -11.100 1.00 20.51 ? 304 LEU B CG 1 ATOM 5723 C CD1 . LEU B 1 304 ? 34.880 -7.786 -9.847 1.00 16.04 ? 304 LEU B CD1 1 ATOM 5724 C CD2 . LEU B 1 304 ? 33.241 -8.403 -11.573 1.00 21.53 ? 304 LEU B CD2 1 ATOM 5725 N N . THR B 1 305 ? 37.911 -8.415 -14.437 1.00 22.32 ? 305 THR B N 1 ATOM 5726 C CA . THR B 1 305 ? 38.931 -7.763 -15.262 1.00 23.03 ? 305 THR B CA 1 ATOM 5727 C C . THR B 1 305 ? 39.260 -8.448 -16.576 1.00 23.02 ? 305 THR B C 1 ATOM 5728 O O . THR B 1 305 ? 40.181 -7.994 -17.271 1.00 24.32 ? 305 THR B O 1 ATOM 5729 C CB . THR B 1 305 ? 40.270 -7.624 -14.494 1.00 23.03 ? 305 THR B CB 1 ATOM 5730 O OG1 . THR B 1 305 ? 40.776 -8.922 -14.200 1.00 23.17 ? 305 THR B OG1 1 ATOM 5731 C CG2 . THR B 1 305 ? 40.120 -6.817 -13.222 1.00 22.63 ? 305 THR B CG2 1 ATOM 5732 N N . HIS B 1 306 ? 38.570 -9.557 -16.903 1.00 23.95 ? 306 HIS B N 1 ATOM 5733 C CA . HIS B 1 306 ? 38.818 -10.335 -18.146 1.00 22.88 ? 306 HIS B CA 1 ATOM 5734 C C . HIS B 1 306 ? 40.294 -10.631 -18.337 1.00 24.48 ? 306 HIS B C 1 ATOM 5735 O O . HIS B 1 306 ? 40.845 -10.423 -19.432 1.00 24.47 ? 306 HIS B O 1 ATOM 5736 C CB . HIS B 1 306 ? 38.305 -9.570 -19.378 1.00 22.19 ? 306 HIS B CB 1 ATOM 5737 C CG . HIS B 1 306 ? 37.029 -8.843 -19.126 1.00 20.93 ? 306 HIS B CG 1 ATOM 5738 N ND1 . HIS B 1 306 ? 35.832 -9.501 -18.951 1.00 21.45 ? 306 HIS B ND1 1 ATOM 5739 C CD2 . HIS B 1 306 ? 36.772 -7.527 -18.933 1.00 23.39 ? 306 HIS B CD2 1 ATOM 5740 C CE1 . HIS B 1 306 ? 34.875 -8.620 -18.710 1.00 22.34 ? 306 HIS B CE1 1 ATOM 5741 N NE2 . HIS B 1 306 ? 35.421 -7.415 -18.685 1.00 25.74 ? 306 HIS B NE2 1 ATOM 5742 N N . SER B 1 307 ? 40.924 -11.095 -17.261 1.00 24.72 ? 307 SER B N 1 ATOM 5743 C CA . SER B 1 307 ? 42.353 -11.350 -17.227 1.00 25.18 ? 307 SER B CA 1 ATOM 5744 C C . SER B 1 307 ? 42.549 -12.670 -16.547 1.00 24.72 ? 307 SER B C 1 ATOM 5745 O O . SER B 1 307 ? 41.687 -13.072 -15.788 1.00 24.14 ? 307 SER B O 1 ATOM 5746 C CB . SER B 1 307 ? 43.053 -10.258 -16.398 1.00 25.99 ? 307 SER B CB 1 ATOM 5747 O OG . SER B 1 307 ? 42.557 -8.976 -16.796 1.00 28.81 ? 307 SER B OG 1 ATOM 5748 N N . PRO B 1 308 ? 43.692 -13.329 -16.790 1.00 24.25 ? 308 PRO B N 1 ATOM 5749 C CA . PRO B 1 308 ? 44.071 -14.588 -16.142 1.00 24.62 ? 308 PRO B CA 1 ATOM 5750 C C . PRO B 1 308 ? 44.051 -14.524 -14.590 1.00 25.31 ? 308 PRO B C 1 ATOM 5751 O O . PRO B 1 308 ? 44.444 -13.511 -14.000 1.00 24.83 ? 308 PRO B O 1 ATOM 5752 C CB . PRO B 1 308 ? 45.512 -14.842 -16.647 1.00 24.42 ? 308 PRO B CB 1 ATOM 5753 C CG . PRO B 1 308 ? 45.686 -13.912 -17.864 1.00 25.54 ? 308 PRO B CG 1 ATOM 5754 C CD . PRO B 1 308 ? 44.780 -12.750 -17.610 1.00 25.11 ? 308 PRO B CD 1 ATOM 5755 N N . VAL B 1 309 ? 43.586 -15.612 -13.963 1.00 26.08 ? 309 VAL B N 1 ATOM 5756 C CA . VAL B 1 309 ? 43.538 -15.780 -12.501 1.00 25.13 ? 309 VAL B CA 1 ATOM 5757 C C . VAL B 1 309 ? 44.968 -15.691 -11.956 1.00 25.94 ? 309 VAL B C 1 ATOM 5758 O O . VAL B 1 309 ? 45.856 -16.351 -12.479 1.00 25.18 ? 309 VAL B O 1 ATOM 5759 C CB . VAL B 1 309 ? 42.964 -17.162 -12.116 1.00 24.64 ? 309 VAL B CB 1 ATOM 5760 C CG1 . VAL B 1 309 ? 42.818 -17.280 -10.600 1.00 22.72 ? 309 VAL B CG1 1 ATOM 5761 C CG2 . VAL B 1 309 ? 41.617 -17.406 -12.793 1.00 22.41 ? 309 VAL B CG2 1 ATOM 5762 N N . HIS B 1 310 ? 45.179 -14.807 -10.975 1.00 26.48 ? 310 HIS B N 1 ATOM 5763 C CA . HIS B 1 310 ? 46.408 -14.787 -10.169 1.00 27.92 ? 310 HIS B CA 1 ATOM 5764 C C . HIS B 1 310 ? 46.064 -15.270 -8.762 1.00 26.77 ? 310 HIS B C 1 ATOM 5765 O O . HIS B 1 310 ? 45.431 -14.554 -7.968 1.00 26.35 ? 310 HIS B O 1 ATOM 5766 C CB . HIS B 1 310 ? 47.078 -13.421 -10.190 1.00 28.41 ? 310 HIS B CB 1 ATOM 5767 C CG . HIS B 1 310 ? 47.248 -12.877 -11.576 1.00 36.23 ? 310 HIS B CG 1 ATOM 5768 N ND1 . HIS B 1 310 ? 46.503 -11.811 -12.064 1.00 39.85 ? 310 HIS B ND1 1 ATOM 5769 C CD2 . HIS B 1 310 ? 48.042 -13.286 -12.606 1.00 40.40 ? 310 HIS B CD2 1 ATOM 5770 C CE1 . HIS B 1 310 ? 46.856 -11.571 -13.319 1.00 40.35 ? 310 HIS B CE1 1 ATOM 5771 N NE2 . HIS B 1 310 ? 47.788 -12.446 -13.669 1.00 40.76 ? 310 HIS B NE2 1 ATOM 5772 N N . ASP B 1 311 ? 46.392 -16.541 -8.524 1.00 26.23 ? 311 ASP B N 1 ATOM 5773 C CA . ASP B 1 311 ? 46.075 -17.222 -7.272 1.00 26.01 ? 311 ASP B CA 1 ATOM 5774 C C . ASP B 1 311 ? 46.902 -18.440 -7.083 1.00 26.33 ? 311 ASP B C 1 ATOM 5775 O O . ASP B 1 311 ? 46.952 -19.270 -7.965 1.00 27.60 ? 311 ASP B O 1 ATOM 5776 C CB . ASP B 1 311 ? 44.648 -17.715 -7.257 1.00 25.11 ? 311 ASP B CB 1 ATOM 5777 C CG . ASP B 1 311 ? 44.286 -18.371 -5.947 1.00 23.97 ? 311 ASP B CG 1 ATOM 5778 O OD1 . ASP B 1 311 ? 43.916 -17.673 -4.951 1.00 25.99 ? 311 ASP B OD1 1 ATOM 5779 O OD2 . ASP B 1 311 ? 44.365 -19.588 -5.918 1.00 21.17 ? 311 ASP B OD2 1 ATOM 5780 N N . ASP B 1 312 ? 47.489 -18.598 -5.909 1.00 26.28 ? 312 ASP B N 1 ATOM 5781 C CA A ASP B 1 312 ? 48.110 -19.872 -5.566 0.50 26.67 ? 312 ASP B CA 1 ATOM 5782 C CA B ASP B 1 312 ? 48.107 -19.877 -5.575 0.50 26.02 ? 312 ASP B CA 1 ATOM 5783 C C . ASP B 1 312 ? 47.552 -20.449 -4.267 1.00 26.13 ? 312 ASP B C 1 ATOM 5784 O O . ASP B 1 312 ? 48.278 -21.042 -3.479 1.00 26.00 ? 312 ASP B O 1 ATOM 5785 C CB A ASP B 1 312 ? 49.639 -19.746 -5.497 0.50 27.48 ? 312 ASP B CB 1 ATOM 5786 C CB B ASP B 1 312 ? 49.644 -19.757 -5.561 0.50 26.30 ? 312 ASP B CB 1 ATOM 5787 C CG A ASP B 1 312 ? 50.335 -21.005 -5.949 0.50 30.72 ? 312 ASP B CG 1 ATOM 5788 C CG B ASP B 1 312 ? 50.213 -19.388 -6.931 0.50 26.78 ? 312 ASP B CG 1 ATOM 5789 O OD1 A ASP B 1 312 ? 49.630 -21.906 -6.478 0.50 35.03 ? 312 ASP B OD1 1 ATOM 5790 O OD1 B ASP B 1 312 ? 49.812 -20.012 -7.943 0.50 27.62 ? 312 ASP B OD1 1 ATOM 5791 O OD2 A ASP B 1 312 ? 51.571 -21.102 -5.779 0.50 33.99 ? 312 ASP B OD2 1 ATOM 5792 O OD2 B ASP B 1 312 ? 51.063 -18.472 -7.002 0.50 28.12 ? 312 ASP B OD2 1 ATOM 5793 N N . THR B 1 313 ? 46.243 -20.299 -4.044 1.00 24.21 ? 313 THR B N 1 ATOM 5794 C CA . THR B 1 313 ? 45.646 -20.908 -2.833 1.00 21.96 ? 313 THR B CA 1 ATOM 5795 C C . THR B 1 313 ? 44.760 -22.137 -3.142 1.00 21.87 ? 313 THR B C 1 ATOM 5796 O O . THR B 1 313 ? 45.263 -23.267 -3.248 1.00 21.61 ? 313 THR B O 1 ATOM 5797 C CB . THR B 1 313 ? 44.854 -19.878 -2.027 1.00 21.06 ? 313 THR B CB 1 ATOM 5798 O OG1 . THR B 1 313 ? 43.688 -19.464 -2.765 1.00 18.05 ? 313 THR B OG1 1 ATOM 5799 C CG2 . THR B 1 313 ? 45.773 -18.654 -1.696 1.00 18.91 ? 313 THR B CG2 1 ATOM 5800 N N . SER B 1 314 ? 43.448 -21.915 -3.282 1.00 20.60 ? 314 SER B N 1 ATOM 5801 C CA . SER B 1 314 ? 42.534 -23.025 -3.513 1.00 20.96 ? 314 SER B CA 1 ATOM 5802 C C . SER B 1 314 ? 42.263 -23.226 -4.998 1.00 21.48 ? 314 SER B C 1 ATOM 5803 O O . SER B 1 314 ? 41.571 -24.154 -5.348 1.00 22.47 ? 314 SER B O 1 ATOM 5804 C CB . SER B 1 314 ? 41.209 -22.808 -2.771 1.00 19.86 ? 314 SER B CB 1 ATOM 5805 O OG . SER B 1 314 ? 40.608 -21.615 -3.217 1.00 20.57 ? 314 SER B OG 1 ATOM 5806 N N . SER B 1 315 ? 42.777 -22.376 -5.886 1.00 21.81 ? 315 SER B N 1 ATOM 5807 C CA . SER B 1 315 ? 42.442 -22.569 -7.298 1.00 22.68 ? 315 SER B CA 1 ATOM 5808 C C . SER B 1 315 ? 43.153 -23.774 -7.959 1.00 23.28 ? 315 SER B C 1 ATOM 5809 O O . SER B 1 315 ? 44.291 -24.127 -7.610 1.00 23.65 ? 315 SER B O 1 ATOM 5810 C CB . SER B 1 315 ? 42.626 -21.288 -8.120 1.00 21.85 ? 315 SER B CB 1 ATOM 5811 O OG . SER B 1 315 ? 43.990 -21.080 -8.376 1.00 23.07 ? 315 SER B OG 1 ATOM 5812 N N . ASN B 1 316 ? 42.442 -24.423 -8.868 1.00 24.19 ? 316 ASN B N 1 ATOM 5813 C CA . ASN B 1 316 ? 43.032 -25.422 -9.709 1.00 25.14 ? 316 ASN B CA 1 ATOM 5814 C C . ASN B 1 316 ? 43.493 -24.738 -11.036 1.00 26.05 ? 316 ASN B C 1 ATOM 5815 O O . ASN B 1 316 ? 42.665 -24.210 -11.791 1.00 25.79 ? 316 ASN B O 1 ATOM 5816 C CB . ASN B 1 316 ? 42.023 -26.541 -9.912 1.00 25.84 ? 316 ASN B CB 1 ATOM 5817 C CG . ASN B 1 316 ? 42.551 -27.674 -10.762 1.00 25.98 ? 316 ASN B CG 1 ATOM 5818 O OD1 . ASN B 1 316 ? 43.352 -27.463 -11.670 1.00 28.88 ? 316 ASN B OD1 1 ATOM 5819 N ND2 . ASN B 1 316 ? 42.101 -28.881 -10.477 1.00 27.39 ? 316 ASN B ND2 1 ATOM 5820 N N . HIS B 1 317 ? 44.813 -24.736 -11.246 1.00 25.50 ? 317 HIS B N 1 ATOM 5821 C CA . HIS B 1 317 ? 45.516 -24.118 -12.348 1.00 26.84 ? 317 HIS B CA 1 ATOM 5822 C C . HIS B 1 317 ? 45.256 -24.850 -13.688 1.00 27.15 ? 317 HIS B C 1 ATOM 5823 O O . HIS B 1 317 ? 45.277 -24.234 -14.770 1.00 26.28 ? 317 HIS B O 1 ATOM 5824 C CB . HIS B 1 317 ? 47.023 -24.151 -12.068 1.00 27.09 ? 317 HIS B CB 1 ATOM 5825 C CG . HIS B 1 317 ? 47.446 -23.333 -10.877 1.00 32.24 ? 317 HIS B CG 1 ATOM 5826 N ND1 . HIS B 1 317 ? 47.218 -21.970 -10.780 1.00 37.54 ? 317 HIS B ND1 1 ATOM 5827 C CD2 . HIS B 1 317 ? 48.079 -23.686 -9.731 1.00 35.58 ? 317 HIS B CD2 1 ATOM 5828 C CE1 . HIS B 1 317 ? 47.694 -21.526 -9.630 1.00 35.73 ? 317 HIS B CE1 1 ATOM 5829 N NE2 . HIS B 1 317 ? 48.229 -22.545 -8.979 1.00 36.48 ? 317 HIS B NE2 1 ATOM 5830 N N . THR B 1 318 ? 45.016 -26.158 -13.621 1.00 27.05 ? 318 THR B N 1 ATOM 5831 C CA . THR B 1 318 ? 44.678 -26.866 -14.836 1.00 27.53 ? 318 THR B CA 1 ATOM 5832 C C . THR B 1 318 ? 43.339 -26.332 -15.338 1.00 27.34 ? 318 THR B C 1 ATOM 5833 O O . THR B 1 318 ? 43.212 -25.954 -16.508 1.00 28.05 ? 318 THR B O 1 ATOM 5834 C CB . THR B 1 318 ? 44.580 -28.340 -14.607 1.00 27.05 ? 318 THR B CB 1 ATOM 5835 O OG1 . THR B 1 318 ? 45.838 -28.800 -14.132 1.00 28.70 ? 318 THR B OG1 1 ATOM 5836 C CG2 . THR B 1 318 ? 44.261 -29.031 -15.933 1.00 28.45 ? 318 THR B CG2 1 ATOM 5837 N N . LEU B 1 319 ? 42.358 -26.285 -14.439 1.00 26.43 ? 319 LEU B N 1 ATOM 5838 C CA . LEU B 1 319 ? 41.052 -25.797 -14.756 1.00 25.27 ? 319 LEU B CA 1 ATOM 5839 C C . LEU B 1 319 ? 41.070 -24.312 -15.168 1.00 26.02 ? 319 LEU B C 1 ATOM 5840 O O . LEU B 1 319 ? 40.344 -23.915 -16.124 1.00 27.02 ? 319 LEU B O 1 ATOM 5841 C CB . LEU B 1 319 ? 40.168 -25.966 -13.548 1.00 24.74 ? 319 LEU B CB 1 ATOM 5842 C CG . LEU B 1 319 ? 39.036 -26.996 -13.426 1.00 25.72 ? 319 LEU B CG 1 ATOM 5843 C CD1 . LEU B 1 319 ? 39.094 -28.170 -14.433 1.00 25.30 ? 319 LEU B CD1 1 ATOM 5844 C CD2 . LEU B 1 319 ? 38.924 -27.481 -11.993 1.00 21.36 ? 319 LEU B CD2 1 ATOM 5845 N N . ASP B 1 320 ? 41.868 -23.485 -14.483 1.00 24.19 ? 320 ASP B N 1 ATOM 5846 C CA . ASP B 1 320 ? 41.654 -22.066 -14.598 1.00 23.98 ? 320 ASP B CA 1 ATOM 5847 C C . ASP B 1 320 ? 42.499 -21.466 -15.732 1.00 24.56 ? 320 ASP B C 1 ATOM 5848 O O . ASP B 1 320 ? 42.279 -20.319 -16.111 1.00 24.82 ? 320 ASP B O 1 ATOM 5849 C CB . ASP B 1 320 ? 41.914 -21.315 -13.257 1.00 22.49 ? 320 ASP B CB 1 ATOM 5850 C CG . ASP B 1 320 ? 40.735 -21.345 -12.311 1.00 23.99 ? 320 ASP B CG 1 ATOM 5851 O OD1 . ASP B 1 320 ? 39.881 -22.236 -12.433 1.00 22.95 ? 320 ASP B OD1 1 ATOM 5852 O OD2 . ASP B 1 320 ? 40.636 -20.474 -11.402 1.00 24.86 ? 320 ASP B OD2 1 ATOM 5853 N N . SER B 1 321 ? 43.507 -22.169 -16.217 1.00 25.24 ? 321 SER B N 1 ATOM 5854 C CA . SER B 1 321 ? 44.327 -21.541 -17.251 1.00 27.38 ? 321 SER B CA 1 ATOM 5855 C C . SER B 1 321 ? 43.789 -21.873 -18.682 1.00 27.94 ? 321 SER B C 1 ATOM 5856 O O . SER B 1 321 ? 44.328 -21.401 -19.675 1.00 28.03 ? 321 SER B O 1 ATOM 5857 C CB . SER B 1 321 ? 45.823 -21.870 -17.068 1.00 27.39 ? 321 SER B CB 1 ATOM 5858 O OG . SER B 1 321 ? 46.052 -23.220 -17.356 1.00 28.00 ? 321 SER B OG 1 ATOM 5859 N N . SER B 1 322 ? 42.704 -22.660 -18.758 1.00 28.62 ? 322 SER B N 1 ATOM 5860 C CA . SER B 1 322 ? 42.063 -23.039 -20.029 1.00 28.61 ? 322 SER B CA 1 ATOM 5861 C C . SER B 1 322 ? 40.703 -22.375 -20.238 1.00 28.09 ? 322 SER B C 1 ATOM 5862 O O . SER B 1 322 ? 39.811 -22.525 -19.393 1.00 27.85 ? 322 SER B O 1 ATOM 5863 C CB . SER B 1 322 ? 41.912 -24.555 -20.102 1.00 29.12 ? 322 SER B CB 1 ATOM 5864 O OG . SER B 1 322 ? 40.830 -24.932 -20.948 1.00 32.40 ? 322 SER B OG 1 ATOM 5865 N N . PRO B 1 323 ? 40.523 -21.678 -21.390 1.00 27.69 ? 323 PRO B N 1 ATOM 5866 C CA . PRO B 1 323 ? 39.281 -20.948 -21.701 1.00 26.80 ? 323 PRO B CA 1 ATOM 5867 C C . PRO B 1 323 ? 38.023 -21.819 -21.675 1.00 26.74 ? 323 PRO B C 1 ATOM 5868 O O . PRO B 1 323 ? 36.961 -21.323 -21.356 1.00 27.31 ? 323 PRO B O 1 ATOM 5869 C CB . PRO B 1 323 ? 39.510 -20.387 -23.114 1.00 26.97 ? 323 PRO B CB 1 ATOM 5870 C CG . PRO B 1 323 ? 40.974 -20.352 -23.290 1.00 29.70 ? 323 PRO B CG 1 ATOM 5871 C CD . PRO B 1 323 ? 41.550 -21.508 -22.441 1.00 27.24 ? 323 PRO B CD 1 ATOM 5872 N N . ALA B 1 324 ? 38.168 -23.096 -21.999 1.00 26.23 ? 324 ALA B N 1 ATOM 5873 C CA . ALA B 1 324 ? 37.130 -24.128 -21.894 1.00 25.77 ? 324 ALA B CA 1 ATOM 5874 C C . ALA B 1 324 ? 36.523 -24.324 -20.516 1.00 25.03 ? 324 ALA B C 1 ATOM 5875 O O . ALA B 1 324 ? 35.330 -24.568 -20.408 1.00 25.55 ? 324 ALA B O 1 ATOM 5876 C CB . ALA B 1 324 ? 37.682 -25.494 -22.368 1.00 25.06 ? 324 ALA B CB 1 ATOM 5877 N N . THR B 1 325 ? 37.373 -24.309 -19.488 1.00 24.03 ? 325 THR B N 1 ATOM 5878 C CA . THR B 1 325 ? 36.946 -24.573 -18.128 1.00 22.68 ? 325 THR B CA 1 ATOM 5879 C C . THR B 1 325 ? 37.021 -23.311 -17.241 1.00 22.40 ? 325 THR B C 1 ATOM 5880 O O . THR B 1 325 ? 36.511 -23.309 -16.115 1.00 23.04 ? 325 THR B O 1 ATOM 5881 C CB . THR B 1 325 ? 37.717 -25.748 -17.488 1.00 22.24 ? 325 THR B CB 1 ATOM 5882 O OG1 . THR B 1 325 ? 39.105 -25.605 -17.747 1.00 21.60 ? 325 THR B OG1 1 ATOM 5883 C CG2 . THR B 1 325 ? 37.267 -27.086 -18.087 1.00 23.00 ? 325 THR B CG2 1 ATOM 5884 N N . PHE B 1 326 ? 37.646 -22.258 -17.746 1.00 20.89 ? 326 PHE B N 1 ATOM 5885 C CA . PHE B 1 326 ? 37.574 -20.954 -17.105 1.00 20.82 ? 326 PHE B CA 1 ATOM 5886 C C . PHE B 1 326 ? 37.567 -19.778 -18.151 1.00 21.87 ? 326 PHE B C 1 ATOM 5887 O O . PHE B 1 326 ? 38.600 -19.082 -18.302 1.00 21.39 ? 326 PHE B O 1 ATOM 5888 C CB . PHE B 1 326 ? 38.669 -20.780 -16.027 1.00 19.63 ? 326 PHE B CB 1 ATOM 5889 C CG . PHE B 1 326 ? 38.376 -19.634 -15.033 1.00 20.02 ? 326 PHE B CG 1 ATOM 5890 C CD1 . PHE B 1 326 ? 37.558 -19.854 -13.926 1.00 17.89 ? 326 PHE B CD1 1 ATOM 5891 C CD2 . PHE B 1 326 ? 38.827 -18.333 -15.276 1.00 16.69 ? 326 PHE B CD2 1 ATOM 5892 C CE1 . PHE B 1 326 ? 37.256 -18.820 -13.045 1.00 16.97 ? 326 PHE B CE1 1 ATOM 5893 C CE2 . PHE B 1 326 ? 38.516 -17.261 -14.387 1.00 19.78 ? 326 PHE B CE2 1 ATOM 5894 C CZ . PHE B 1 326 ? 37.740 -17.514 -13.261 1.00 17.89 ? 326 PHE B CZ 1 ATOM 5895 N N . PRO B 1 327 ? 36.410 -19.563 -18.860 1.00 21.77 ? 327 PRO B N 1 ATOM 5896 C CA . PRO B 1 327 ? 36.296 -18.541 -19.872 1.00 22.16 ? 327 PRO B CA 1 ATOM 5897 C C . PRO B 1 327 ? 36.202 -17.154 -19.254 1.00 22.41 ? 327 PRO B C 1 ATOM 5898 O O . PRO B 1 327 ? 35.418 -16.931 -18.283 1.00 21.76 ? 327 PRO B O 1 ATOM 5899 C CB . PRO B 1 327 ? 34.969 -18.909 -20.592 1.00 23.22 ? 327 PRO B CB 1 ATOM 5900 C CG . PRO B 1 327 ? 34.174 -19.597 -19.603 1.00 21.66 ? 327 PRO B CG 1 ATOM 5901 C CD . PRO B 1 327 ? 35.154 -20.325 -18.732 1.00 22.10 ? 327 PRO B CD 1 ATOM 5902 N N . LEU B 1 328 ? 36.948 -16.212 -19.822 1.00 21.80 ? 328 LEU B N 1 ATOM 5903 C CA . LEU B 1 328 ? 37.072 -14.876 -19.206 1.00 22.20 ? 328 LEU B CA 1 ATOM 5904 C C . LEU B 1 328 ? 36.052 -13.829 -19.612 1.00 22.60 ? 328 LEU B C 1 ATOM 5905 O O . LEU B 1 328 ? 36.044 -12.715 -19.055 1.00 22.15 ? 328 LEU B O 1 ATOM 5906 C CB . LEU B 1 328 ? 38.497 -14.327 -19.427 1.00 22.18 ? 328 LEU B CB 1 ATOM 5907 C CG . LEU B 1 328 ? 39.545 -15.283 -18.817 1.00 22.57 ? 328 LEU B CG 1 ATOM 5908 C CD1 . LEU B 1 328 ? 40.962 -14.920 -19.182 1.00 18.32 ? 328 LEU B CD1 1 ATOM 5909 C CD2 . LEU B 1 328 ? 39.334 -15.299 -17.300 1.00 20.27 ? 328 LEU B CD2 1 ATOM 5910 N N . ASN B 1 329 ? 35.188 -14.172 -20.560 1.00 22.92 ? 329 ASN B N 1 ATOM 5911 C CA . ASN B 1 329 ? 34.314 -13.187 -21.195 1.00 25.30 ? 329 ASN B CA 1 ATOM 5912 C C . ASN B 1 329 ? 32.916 -13.666 -21.460 1.00 24.52 ? 329 ASN B C 1 ATOM 5913 O O . ASN B 1 329 ? 32.389 -13.391 -22.525 1.00 25.86 ? 329 ASN B O 1 ATOM 5914 C CB . ASN B 1 329 ? 34.911 -12.766 -22.551 1.00 26.28 ? 329 ASN B CB 1 ATOM 5915 C CG . ASN B 1 329 ? 35.931 -11.687 -22.396 1.00 32.66 ? 329 ASN B CG 1 ATOM 5916 O OD1 . ASN B 1 329 ? 35.626 -10.619 -21.822 1.00 38.58 ? 329 ASN B OD1 1 ATOM 5917 N ND2 . ASN B 1 329 ? 37.173 -11.942 -22.876 1.00 35.42 ? 329 ASN B ND2 1 ATOM 5918 N N . SER B 1 330 ? 32.300 -14.359 -20.512 1.00 22.61 ? 330 SER B N 1 ATOM 5919 C CA . SER B 1 330 ? 31.064 -15.066 -20.794 1.00 19.84 ? 330 SER B CA 1 ATOM 5920 C C . SER B 1 330 ? 29.888 -14.260 -20.335 1.00 18.52 ? 330 SER B C 1 ATOM 5921 O O . SER B 1 330 ? 28.792 -14.741 -20.427 1.00 18.33 ? 330 SER B O 1 ATOM 5922 C CB . SER B 1 330 ? 31.030 -16.334 -19.955 1.00 19.99 ? 330 SER B CB 1 ATOM 5923 O OG . SER B 1 330 ? 32.232 -17.030 -20.100 1.00 20.87 ? 330 SER B OG 1 ATOM 5924 N N . THR B 1 331 ? 30.153 -13.119 -19.702 1.00 16.44 ? 331 THR B N 1 ATOM 5925 C CA . THR B 1 331 ? 29.130 -12.188 -19.225 1.00 16.64 ? 331 THR B CA 1 ATOM 5926 C C . THR B 1 331 ? 28.253 -12.680 -18.076 1.00 16.86 ? 331 THR B C 1 ATOM 5927 O O . THR B 1 331 ? 27.924 -11.898 -17.150 1.00 18.25 ? 331 THR B O 1 ATOM 5928 C CB . THR B 1 331 ? 28.230 -11.611 -20.403 1.00 16.65 ? 331 THR B CB 1 ATOM 5929 O OG1 . THR B 1 331 ? 29.068 -10.949 -21.348 1.00 18.66 ? 331 THR B OG1 1 ATOM 5930 C CG2 . THR B 1 331 ? 27.238 -10.665 -19.911 1.00 12.97 ? 331 THR B CG2 1 ATOM 5931 N N . LEU B 1 332 ? 27.826 -13.927 -18.139 1.00 15.87 ? 332 LEU B N 1 ATOM 5932 C CA . LEU B 1 332 ? 27.015 -14.481 -17.067 1.00 16.46 ? 332 LEU B CA 1 ATOM 5933 C C . LEU B 1 332 ? 27.659 -15.724 -16.550 1.00 16.47 ? 332 LEU B C 1 ATOM 5934 O O . LEU B 1 332 ? 28.095 -16.580 -17.342 1.00 16.85 ? 332 LEU B O 1 ATOM 5935 C CB . LEU B 1 332 ? 25.609 -14.786 -17.550 1.00 16.56 ? 332 LEU B CB 1 ATOM 5936 C CG . LEU B 1 332 ? 24.773 -13.620 -18.079 1.00 16.92 ? 332 LEU B CG 1 ATOM 5937 C CD1 . LEU B 1 332 ? 23.533 -14.188 -18.708 1.00 17.62 ? 332 LEU B CD1 1 ATOM 5938 C CD2 . LEU B 1 332 ? 24.371 -12.664 -16.981 1.00 15.87 ? 332 LEU B CD2 1 ATOM 5939 N N . TYR B 1 333 ? 27.720 -15.831 -15.224 1.00 16.20 ? 333 TYR B N 1 ATOM 5940 C CA . TYR B 1 333 ? 28.343 -16.978 -14.555 1.00 14.67 ? 333 TYR B CA 1 ATOM 5941 C C . TYR B 1 333 ? 27.436 -17.439 -13.398 1.00 15.89 ? 333 TYR B C 1 ATOM 5942 O O . TYR B 1 333 ? 26.683 -16.658 -12.816 1.00 15.07 ? 333 TYR B O 1 ATOM 5943 C CB . TYR B 1 333 ? 29.705 -16.598 -13.998 1.00 15.16 ? 333 TYR B CB 1 ATOM 5944 C CG . TYR B 1 333 ? 30.781 -16.182 -15.022 1.00 13.44 ? 333 TYR B CG 1 ATOM 5945 C CD1 . TYR B 1 333 ? 31.637 -17.106 -15.553 1.00 12.12 ? 333 TYR B CD1 1 ATOM 5946 C CD2 . TYR B 1 333 ? 30.919 -14.850 -15.427 1.00 14.32 ? 333 TYR B CD2 1 ATOM 5947 C CE1 . TYR B 1 333 ? 32.634 -16.745 -16.483 1.00 10.30 ? 333 TYR B CE1 1 ATOM 5948 C CE2 . TYR B 1 333 ? 31.906 -14.466 -16.345 1.00 13.91 ? 333 TYR B CE2 1 ATOM 5949 C CZ . TYR B 1 333 ? 32.746 -15.428 -16.879 1.00 14.68 ? 333 TYR B CZ 1 ATOM 5950 O OH . TYR B 1 333 ? 33.722 -15.061 -17.796 1.00 13.14 ? 333 TYR B OH 1 ATOM 5951 N N . ALA B 1 334 ? 27.454 -18.743 -13.117 1.00 16.05 ? 334 ALA B N 1 ATOM 5952 C CA . ALA B 1 334 ? 26.668 -19.284 -12.025 1.00 16.18 ? 334 ALA B CA 1 ATOM 5953 C C . ALA B 1 334 ? 27.562 -20.335 -11.394 1.00 17.11 ? 334 ALA B C 1 ATOM 5954 O O . ALA B 1 334 ? 28.238 -21.136 -12.147 1.00 18.08 ? 334 ALA B O 1 ATOM 5955 C CB . ALA B 1 334 ? 25.325 -19.878 -12.497 1.00 14.36 ? 334 ALA B CB 1 ATOM 5956 N N . ASP B 1 335 ? 27.664 -20.251 -10.050 1.00 16.19 ? 335 ASP B N 1 ATOM 5957 C CA . ASP B 1 335 ? 28.445 -21.207 -9.264 1.00 16.13 ? 335 ASP B CA 1 ATOM 5958 C C . ASP B 1 335 ? 27.581 -21.732 -8.128 1.00 16.27 ? 335 ASP B C 1 ATOM 5959 O O . ASP B 1 335 ? 26.845 -20.972 -7.531 1.00 15.79 ? 335 ASP B O 1 ATOM 5960 C CB . ASP B 1 335 ? 29.734 -20.555 -8.748 1.00 16.29 ? 335 ASP B CB 1 ATOM 5961 C CG . ASP B 1 335 ? 30.794 -20.370 -9.830 1.00 17.41 ? 335 ASP B CG 1 ATOM 5962 O OD1 . ASP B 1 335 ? 31.027 -21.327 -10.627 1.00 18.75 ? 335 ASP B OD1 1 ATOM 5963 O OD2 . ASP B 1 335 ? 31.447 -19.276 -9.862 1.00 16.19 ? 335 ASP B OD2 1 ATOM 5964 N N . PHE B 1 336 ? 27.693 -23.032 -7.840 1.00 16.65 ? 336 PHE B N 1 ATOM 5965 C CA . PHE B 1 336 ? 26.863 -23.710 -6.801 1.00 17.47 ? 336 PHE B CA 1 ATOM 5966 C C . PHE B 1 336 ? 27.748 -24.404 -5.762 1.00 17.99 ? 336 PHE B C 1 ATOM 5967 O O . PHE B 1 336 ? 28.702 -25.125 -6.130 1.00 16.71 ? 336 PHE B O 1 ATOM 5968 C CB . PHE B 1 336 ? 25.887 -24.756 -7.425 1.00 16.95 ? 336 PHE B CB 1 ATOM 5969 C CG . PHE B 1 336 ? 24.916 -24.119 -8.344 1.00 15.94 ? 336 PHE B CG 1 ATOM 5970 C CD1 . PHE B 1 336 ? 25.326 -23.769 -9.634 1.00 14.38 ? 336 PHE B CD1 1 ATOM 5971 C CD2 . PHE B 1 336 ? 23.644 -23.716 -7.870 1.00 13.19 ? 336 PHE B CD2 1 ATOM 5972 C CE1 . PHE B 1 336 ? 24.474 -23.094 -10.490 1.00 11.93 ? 336 PHE B CE1 1 ATOM 5973 C CE2 . PHE B 1 336 ? 22.771 -23.005 -8.698 1.00 13.87 ? 336 PHE B CE2 1 ATOM 5974 C CZ . PHE B 1 336 ? 23.205 -22.694 -10.022 1.00 14.69 ? 336 PHE B CZ 1 ATOM 5975 N N . SER B 1 337 ? 27.435 -24.186 -4.476 1.00 17.13 ? 337 SER B N 1 ATOM 5976 C CA . SER B 1 337 ? 28.333 -24.701 -3.413 1.00 17.88 ? 337 SER B CA 1 ATOM 5977 C C . SER B 1 337 ? 27.599 -24.934 -2.117 1.00 17.73 ? 337 SER B C 1 ATOM 5978 O O . SER B 1 337 ? 26.327 -24.959 -2.105 1.00 18.25 ? 337 SER B O 1 ATOM 5979 C CB . SER B 1 337 ? 29.498 -23.721 -3.212 1.00 17.13 ? 337 SER B CB 1 ATOM 5980 O OG . SER B 1 337 ? 30.544 -24.351 -2.538 1.00 18.59 ? 337 SER B OG 1 ATOM 5981 N N . HIS B 1 338 ? 28.401 -25.081 -1.054 1.00 17.34 ? 338 HIS B N 1 ATOM 5982 C CA . HIS B 1 338 ? 27.965 -25.300 0.328 1.00 17.19 ? 338 HIS B CA 1 ATOM 5983 C C . HIS B 1 338 ? 28.031 -23.963 1.121 1.00 17.47 ? 338 HIS B C 1 ATOM 5984 O O . HIS B 1 338 ? 28.779 -23.059 0.754 1.00 16.21 ? 338 HIS B O 1 ATOM 5985 C CB . HIS B 1 338 ? 28.892 -26.317 1.019 1.00 16.04 ? 338 HIS B CB 1 ATOM 5986 C CG . HIS B 1 338 ? 28.984 -27.646 0.339 1.00 17.31 ? 338 HIS B CG 1 ATOM 5987 N ND1 . HIS B 1 338 ? 28.106 -28.678 0.607 1.00 10.84 ? 338 HIS B ND1 1 ATOM 5988 C CD2 . HIS B 1 338 ? 29.878 -28.134 -0.560 1.00 17.27 ? 338 HIS B CD2 1 ATOM 5989 C CE1 . HIS B 1 338 ? 28.436 -29.737 -0.114 1.00 13.90 ? 338 HIS B CE1 1 ATOM 5990 N NE2 . HIS B 1 338 ? 29.519 -29.442 -0.817 1.00 17.09 ? 338 HIS B NE2 1 ATOM 5991 N N . ASP B 1 339 ? 27.268 -23.862 2.209 1.00 17.49 ? 339 ASP B N 1 ATOM 5992 C CA . ASP B 1 339 ? 27.271 -22.684 3.035 1.00 17.39 ? 339 ASP B CA 1 ATOM 5993 C C . ASP B 1 339 ? 28.654 -22.329 3.602 1.00 17.74 ? 339 ASP B C 1 ATOM 5994 O O . ASP B 1 339 ? 28.990 -21.171 3.720 1.00 19.33 ? 339 ASP B O 1 ATOM 5995 C CB . ASP B 1 339 ? 26.271 -22.833 4.179 1.00 17.98 ? 339 ASP B CB 1 ATOM 5996 C CG . ASP B 1 339 ? 26.514 -24.055 5.050 1.00 21.00 ? 339 ASP B CG 1 ATOM 5997 O OD1 . ASP B 1 339 ? 27.533 -24.778 4.951 1.00 26.57 ? 339 ASP B OD1 1 ATOM 5998 O OD2 . ASP B 1 339 ? 25.621 -24.339 5.826 1.00 24.98 ? 339 ASP B OD2 1 ATOM 5999 N N . ASN B 1 340 ? 29.485 -23.301 3.927 1.00 16.79 ? 340 ASN B N 1 ATOM 6000 C CA . ASN B 1 340 ? 30.734 -22.968 4.626 1.00 16.49 ? 340 ASN B CA 1 ATOM 6001 C C . ASN B 1 340 ? 31.663 -22.237 3.682 1.00 15.91 ? 340 ASN B C 1 ATOM 6002 O O . ASN B 1 340 ? 32.301 -21.252 4.060 1.00 14.58 ? 340 ASN B O 1 ATOM 6003 C CB . ASN B 1 340 ? 31.396 -24.245 5.248 1.00 15.17 ? 340 ASN B CB 1 ATOM 6004 C CG . ASN B 1 340 ? 30.636 -24.752 6.566 1.00 17.14 ? 340 ASN B CG 1 ATOM 6005 O OD1 . ASN B 1 340 ? 29.820 -24.005 7.192 1.00 15.65 ? 340 ASN B OD1 1 ATOM 6006 N ND2 . ASN B 1 340 ? 30.882 -26.007 6.943 1.00 16.79 ? 340 ASN B ND2 1 ATOM 6007 N N . GLY B 1 341 ? 31.765 -22.733 2.453 1.00 14.51 ? 341 GLY B N 1 ATOM 6008 C CA . GLY B 1 341 ? 32.609 -22.065 1.493 1.00 14.16 ? 341 GLY B CA 1 ATOM 6009 C C . GLY B 1 341 ? 32.052 -20.683 1.112 1.00 15.09 ? 341 GLY B C 1 ATOM 6010 O O . GLY B 1 341 ? 32.820 -19.781 0.830 1.00 14.79 ? 341 GLY B O 1 ATOM 6011 N N . ILE B 1 342 ? 30.723 -20.500 1.121 1.00 14.11 ? 342 ILE B N 1 ATOM 6012 C CA . ILE B 1 342 ? 30.113 -19.238 0.728 1.00 14.55 ? 342 ILE B CA 1 ATOM 6013 C C . ILE B 1 342 ? 30.383 -18.196 1.852 1.00 16.76 ? 342 ILE B C 1 ATOM 6014 O O . ILE B 1 342 ? 30.689 -17.021 1.579 1.00 16.72 ? 342 ILE B O 1 ATOM 6015 C CB . ILE B 1 342 ? 28.594 -19.471 0.484 1.00 15.23 ? 342 ILE B CB 1 ATOM 6016 C CG1 . ILE B 1 342 ? 28.402 -20.356 -0.769 1.00 14.61 ? 342 ILE B CG1 1 ATOM 6017 C CG2 . ILE B 1 342 ? 27.807 -18.186 0.429 1.00 12.39 ? 342 ILE B CG2 1 ATOM 6018 C CD1 . ILE B 1 342 ? 26.927 -20.566 -1.095 1.00 9.91 ? 342 ILE B CD1 1 ATOM 6019 N N . ILE B 1 343 ? 30.319 -18.648 3.123 1.00 17.44 ? 343 ILE B N 1 ATOM 6020 C CA . ILE B 1 343 ? 30.707 -17.791 4.242 1.00 15.95 ? 343 ILE B CA 1 ATOM 6021 C C . ILE B 1 343 ? 32.101 -17.266 3.986 1.00 15.45 ? 343 ILE B C 1 ATOM 6022 O O . ILE B 1 343 ? 32.321 -16.022 3.967 1.00 16.09 ? 343 ILE B O 1 ATOM 6023 C CB . ILE B 1 343 ? 30.563 -18.498 5.637 1.00 15.74 ? 343 ILE B CB 1 ATOM 6024 C CG1 . ILE B 1 343 ? 29.079 -18.712 5.952 1.00 14.63 ? 343 ILE B CG1 1 ATOM 6025 C CG2 . ILE B 1 343 ? 31.308 -17.671 6.749 1.00 13.49 ? 343 ILE B CG2 1 ATOM 6026 C CD1 . ILE B 1 343 ? 28.248 -17.432 6.412 1.00 12.24 ? 343 ILE B CD1 1 ATOM 6027 N N . SER B 1 344 ? 33.047 -18.167 3.744 1.00 14.24 ? 344 SER B N 1 ATOM 6028 C CA . SER B 1 344 ? 34.439 -17.719 3.605 1.00 13.80 ? 344 SER B CA 1 ATOM 6029 C C . SER B 1 344 ? 34.614 -16.709 2.487 1.00 14.77 ? 344 SER B C 1 ATOM 6030 O O . SER B 1 344 ? 35.404 -15.772 2.601 1.00 15.63 ? 344 SER B O 1 ATOM 6031 C CB . SER B 1 344 ? 35.407 -18.869 3.452 1.00 13.60 ? 344 SER B CB 1 ATOM 6032 O OG . SER B 1 344 ? 35.229 -19.852 4.496 1.00 13.86 ? 344 SER B OG 1 ATOM 6033 N N . ILE B 1 345 ? 33.839 -16.884 1.416 1.00 14.99 ? 345 ILE B N 1 ATOM 6034 C CA . ILE B 1 345 ? 33.919 -16.030 0.238 1.00 14.33 ? 345 ILE B CA 1 ATOM 6035 C C . ILE B 1 345 ? 33.303 -14.661 0.486 1.00 13.44 ? 345 ILE B C 1 ATOM 6036 O O . ILE B 1 345 ? 33.838 -13.663 0.061 1.00 12.41 ? 345 ILE B O 1 ATOM 6037 C CB . ILE B 1 345 ? 33.230 -16.740 -0.996 1.00 15.52 ? 345 ILE B CB 1 ATOM 6038 C CG1 . ILE B 1 345 ? 34.123 -17.916 -1.474 1.00 13.97 ? 345 ILE B CG1 1 ATOM 6039 C CG2 . ILE B 1 345 ? 32.921 -15.707 -2.087 1.00 11.85 ? 345 ILE B CG2 1 ATOM 6040 C CD1 . ILE B 1 345 ? 33.447 -18.962 -2.397 1.00 11.91 ? 345 ILE B CD1 1 ATOM 6041 N N . LEU B 1 346 ? 32.139 -14.634 1.133 1.00 12.89 ? 346 LEU B N 1 ATOM 6042 C CA . LEU B 1 346 ? 31.555 -13.402 1.521 1.00 13.14 ? 346 LEU B CA 1 ATOM 6043 C C . LEU B 1 346 ? 32.616 -12.523 2.315 1.00 15.11 ? 346 LEU B C 1 ATOM 6044 O O . LEU B 1 346 ? 32.887 -11.348 1.954 1.00 15.19 ? 346 LEU B O 1 ATOM 6045 C CB . LEU B 1 346 ? 30.283 -13.688 2.265 1.00 11.66 ? 346 LEU B CB 1 ATOM 6046 C CG . LEU B 1 346 ? 29.035 -14.266 1.588 1.00 12.85 ? 346 LEU B CG 1 ATOM 6047 C CD1 . LEU B 1 346 ? 27.851 -14.435 2.613 1.00 10.23 ? 346 LEU B CD1 1 ATOM 6048 C CD2 . LEU B 1 346 ? 28.507 -13.375 0.477 1.00 12.34 ? 346 LEU B CD2 1 ATOM 6049 N N . PHE B 1 347 ? 33.283 -13.125 3.313 1.00 14.18 ? 347 PHE B N 1 ATOM 6050 C CA . PHE B 1 347 ? 34.283 -12.436 4.096 1.00 15.70 ? 347 PHE B CA 1 ATOM 6051 C C . PHE B 1 347 ? 35.543 -12.072 3.341 1.00 16.13 ? 347 PHE B C 1 ATOM 6052 O O . PHE B 1 347 ? 36.045 -10.960 3.523 1.00 17.63 ? 347 PHE B O 1 ATOM 6053 C CB . PHE B 1 347 ? 34.630 -13.265 5.354 1.00 15.79 ? 347 PHE B CB 1 ATOM 6054 C CG . PHE B 1 347 ? 33.613 -13.066 6.449 1.00 15.64 ? 347 PHE B CG 1 ATOM 6055 C CD1 . PHE B 1 347 ? 33.693 -11.921 7.286 1.00 13.89 ? 347 PHE B CD1 1 ATOM 6056 C CD2 . PHE B 1 347 ? 32.535 -13.935 6.573 1.00 9.96 ? 347 PHE B CD2 1 ATOM 6057 C CE1 . PHE B 1 347 ? 32.661 -11.686 8.305 1.00 15.62 ? 347 PHE B CE1 1 ATOM 6058 C CE2 . PHE B 1 347 ? 31.540 -13.727 7.573 1.00 15.37 ? 347 PHE B CE2 1 ATOM 6059 C CZ . PHE B 1 347 ? 31.638 -12.596 8.445 1.00 12.02 ? 347 PHE B CZ 1 ATOM 6060 N N . ALA B 1 348 ? 36.014 -12.959 2.467 1.00 14.92 ? 348 ALA B N 1 ATOM 6061 C CA . ALA B 1 348 ? 37.201 -12.650 1.649 1.00 15.82 ? 348 ALA B CA 1 ATOM 6062 C C . ALA B 1 348 ? 36.914 -11.514 0.679 1.00 16.11 ? 348 ALA B C 1 ATOM 6063 O O . ALA B 1 348 ? 37.844 -10.818 0.310 1.00 17.62 ? 348 ALA B O 1 ATOM 6064 C CB . ALA B 1 348 ? 37.661 -13.867 0.878 1.00 14.31 ? 348 ALA B CB 1 ATOM 6065 N N . LEU B 1 349 ? 35.652 -11.314 0.296 1.00 15.25 ? 349 LEU B N 1 ATOM 6066 C CA . LEU B 1 349 ? 35.319 -10.208 -0.612 1.00 17.06 ? 349 LEU B CA 1 ATOM 6067 C C . LEU B 1 349 ? 35.182 -8.881 0.144 1.00 18.06 ? 349 LEU B C 1 ATOM 6068 O O . LEU B 1 349 ? 34.842 -7.854 -0.460 1.00 19.06 ? 349 LEU B O 1 ATOM 6069 C CB . LEU B 1 349 ? 34.022 -10.496 -1.393 1.00 15.12 ? 349 LEU B CB 1 ATOM 6070 C CG . LEU B 1 349 ? 34.158 -11.681 -2.379 1.00 17.61 ? 349 LEU B CG 1 ATOM 6071 C CD1 . LEU B 1 349 ? 32.846 -12.087 -3.019 1.00 16.11 ? 349 LEU B CD1 1 ATOM 6072 C CD2 . LEU B 1 349 ? 35.225 -11.353 -3.472 1.00 18.74 ? 349 LEU B CD2 1 ATOM 6073 N N . GLY B 1 350 ? 35.373 -8.919 1.470 1.00 18.32 ? 350 GLY B N 1 ATOM 6074 C CA . GLY B 1 350 ? 35.271 -7.724 2.269 1.00 19.23 ? 350 GLY B CA 1 ATOM 6075 C C . GLY B 1 350 ? 33.864 -7.355 2.640 1.00 19.47 ? 350 GLY B C 1 ATOM 6076 O O . GLY B 1 350 ? 33.658 -6.330 3.234 1.00 19.85 ? 350 GLY B O 1 ATOM 6077 N N . LEU B 1 351 ? 32.884 -8.175 2.290 1.00 20.19 ? 351 LEU B N 1 ATOM 6078 C CA . LEU B 1 351 ? 31.463 -7.743 2.414 1.00 21.34 ? 351 LEU B CA 1 ATOM 6079 C C . LEU B 1 351 ? 30.945 -7.474 3.828 1.00 21.96 ? 351 LEU B C 1 ATOM 6080 O O . LEU B 1 351 ? 29.879 -6.895 4.021 1.00 23.05 ? 351 LEU B O 1 ATOM 6081 C CB . LEU B 1 351 ? 30.525 -8.718 1.708 1.00 20.01 ? 351 LEU B CB 1 ATOM 6082 C CG . LEU B 1 351 ? 30.872 -8.793 0.218 1.00 22.96 ? 351 LEU B CG 1 ATOM 6083 C CD1 . LEU B 1 351 ? 30.245 -10.020 -0.456 1.00 22.66 ? 351 LEU B CD1 1 ATOM 6084 C CD2 . LEU B 1 351 ? 30.480 -7.483 -0.501 1.00 18.67 ? 351 LEU B CD2 1 ATOM 6085 N N . TYR B 1 352 ? 31.672 -7.946 4.819 1.00 22.60 ? 352 TYR B N 1 ATOM 6086 C CA . TYR B 1 352 ? 31.206 -7.791 6.191 1.00 23.07 ? 352 TYR B CA 1 ATOM 6087 C C . TYR B 1 352 ? 32.317 -7.155 7.031 1.00 23.45 ? 352 TYR B C 1 ATOM 6088 O O . TYR B 1 352 ? 32.506 -7.498 8.200 1.00 22.26 ? 352 TYR B O 1 ATOM 6089 C CB . TYR B 1 352 ? 30.689 -9.121 6.755 1.00 21.35 ? 352 TYR B CB 1 ATOM 6090 C CG . TYR B 1 352 ? 29.393 -9.442 6.066 1.00 22.47 ? 352 TYR B CG 1 ATOM 6091 C CD1 . TYR B 1 352 ? 28.207 -8.800 6.440 1.00 20.84 ? 352 TYR B CD1 1 ATOM 6092 C CD2 . TYR B 1 352 ? 29.360 -10.361 4.980 1.00 17.57 ? 352 TYR B CD2 1 ATOM 6093 C CE1 . TYR B 1 352 ? 27.004 -9.073 5.750 1.00 19.27 ? 352 TYR B CE1 1 ATOM 6094 C CE2 . TYR B 1 352 ? 28.220 -10.618 4.298 1.00 15.79 ? 352 TYR B CE2 1 ATOM 6095 C CZ . TYR B 1 352 ? 27.037 -9.994 4.687 1.00 20.10 ? 352 TYR B CZ 1 ATOM 6096 O OH . TYR B 1 352 ? 25.906 -10.285 3.986 1.00 22.47 ? 352 TYR B OH 1 ATOM 6097 N N . ASN B 1 353 ? 33.028 -6.224 6.393 1.00 22.93 ? 353 ASN B N 1 ATOM 6098 C CA . ASN B 1 353 ? 34.102 -5.524 7.051 1.00 23.79 ? 353 ASN B CA 1 ATOM 6099 C C . ASN B 1 353 ? 33.644 -4.340 7.860 1.00 24.66 ? 353 ASN B C 1 ATOM 6100 O O . ASN B 1 353 ? 34.478 -3.624 8.415 1.00 25.67 ? 353 ASN B O 1 ATOM 6101 C CB . ASN B 1 353 ? 35.180 -5.100 6.073 1.00 22.59 ? 353 ASN B CB 1 ATOM 6102 C CG . ASN B 1 353 ? 36.228 -6.121 5.983 1.00 22.82 ? 353 ASN B CG 1 ATOM 6103 O OD1 . ASN B 1 353 ? 35.959 -7.279 6.333 1.00 21.28 ? 353 ASN B OD1 1 ATOM 6104 N ND2 . ASN B 1 353 ? 37.445 -5.733 5.567 1.00 20.17 ? 353 ASN B ND2 1 ATOM 6105 N N . GLY B 1 354 ? 32.335 -4.146 7.930 1.00 24.80 ? 354 GLY B N 1 ATOM 6106 C CA . GLY B 1 354 ? 31.768 -3.267 8.935 1.00 25.18 ? 354 GLY B CA 1 ATOM 6107 C C . GLY B 1 354 ? 31.200 -4.047 10.116 1.00 25.68 ? 354 GLY B C 1 ATOM 6108 O O . GLY B 1 354 ? 30.469 -3.496 10.923 1.00 26.38 ? 354 GLY B O 1 ATOM 6109 N N . THR B 1 355 ? 31.506 -5.339 10.216 1.00 25.50 ? 355 THR B N 1 ATOM 6110 C CA . THR B 1 355 ? 30.899 -6.181 11.244 1.00 25.04 ? 355 THR B CA 1 ATOM 6111 C C . THR B 1 355 ? 31.928 -6.380 12.386 1.00 26.49 ? 355 THR B C 1 ATOM 6112 O O . THR B 1 355 ? 33.026 -6.916 12.180 1.00 26.72 ? 355 THR B O 1 ATOM 6113 C CB . THR B 1 355 ? 30.412 -7.556 10.670 1.00 25.00 ? 355 THR B CB 1 ATOM 6114 O OG1 . THR B 1 355 ? 29.225 -7.397 9.881 1.00 21.36 ? 355 THR B OG1 1 ATOM 6115 C CG2 . THR B 1 355 ? 30.101 -8.549 11.774 1.00 22.71 ? 355 THR B CG2 1 ATOM 6116 N N . LYS B 1 356 ? 31.580 -5.932 13.582 1.00 26.85 ? 356 LYS B N 1 ATOM 6117 C CA . LYS B 1 356 ? 32.423 -6.196 14.751 1.00 28.55 ? 356 LYS B CA 1 ATOM 6118 C C . LYS B 1 356 ? 32.319 -7.664 15.202 1.00 26.36 ? 356 LYS B C 1 ATOM 6119 O O . LYS B 1 356 ? 31.241 -8.182 15.229 1.00 26.53 ? 356 LYS B O 1 ATOM 6120 C CB . LYS B 1 356 ? 32.081 -5.208 15.896 1.00 28.73 ? 356 LYS B CB 1 ATOM 6121 C CG . LYS B 1 356 ? 32.975 -4.005 15.825 1.00 34.19 ? 356 LYS B CG 1 ATOM 6122 C CD . LYS B 1 356 ? 32.284 -2.628 16.061 1.00 42.33 ? 356 LYS B CD 1 ATOM 6123 C CE . LYS B 1 356 ? 33.042 -1.528 15.192 1.00 46.99 ? 356 LYS B CE 1 ATOM 6124 N NZ . LYS B 1 356 ? 33.177 -0.097 15.745 1.00 49.58 ? 356 LYS B NZ 1 ATOM 6125 N N . PRO B 1 357 ? 33.444 -8.306 15.575 1.00 25.39 ? 357 PRO B N 1 ATOM 6126 C CA . PRO B 1 357 ? 33.440 -9.700 15.983 1.00 24.86 ? 357 PRO B CA 1 ATOM 6127 C C . PRO B 1 357 ? 32.262 -10.014 16.899 1.00 24.60 ? 357 PRO B C 1 ATOM 6128 O O . PRO B 1 357 ? 31.978 -9.243 17.800 1.00 24.33 ? 357 PRO B O 1 ATOM 6129 C CB . PRO B 1 357 ? 34.756 -9.815 16.738 1.00 25.42 ? 357 PRO B CB 1 ATOM 6130 C CG . PRO B 1 357 ? 35.670 -8.965 15.967 1.00 26.32 ? 357 PRO B CG 1 ATOM 6131 C CD . PRO B 1 357 ? 34.802 -7.742 15.634 1.00 25.73 ? 357 PRO B CD 1 ATOM 6132 N N . LEU B 1 358 ? 31.592 -11.131 16.678 1.00 24.20 ? 358 LEU B N 1 ATOM 6133 C CA . LEU B 1 358 ? 30.348 -11.397 17.384 1.00 25.08 ? 358 LEU B CA 1 ATOM 6134 C C . LEU B 1 358 ? 30.644 -11.818 18.804 1.00 26.66 ? 358 LEU B C 1 ATOM 6135 O O . LEU B 1 358 ? 31.588 -12.648 19.036 1.00 26.52 ? 358 LEU B O 1 ATOM 6136 C CB . LEU B 1 358 ? 29.482 -12.478 16.709 1.00 24.04 ? 358 LEU B CB 1 ATOM 6137 C CG . LEU B 1 358 ? 29.075 -12.415 15.244 1.00 24.86 ? 358 LEU B CG 1 ATOM 6138 C CD1 . LEU B 1 358 ? 27.865 -13.325 14.999 1.00 25.12 ? 358 LEU B CD1 1 ATOM 6139 C CD2 . LEU B 1 358 ? 28.822 -11.037 14.749 1.00 22.60 ? 358 LEU B CD2 1 ATOM 6140 N N . SER B 1 359 ? 29.866 -11.228 19.730 1.00 26.84 ? 359 SER B N 1 ATOM 6141 C CA . SER B 1 359 ? 29.944 -11.555 21.154 1.00 27.98 ? 359 SER B CA 1 ATOM 6142 C C . SER B 1 359 ? 29.657 -13.053 21.360 1.00 27.33 ? 359 SER B C 1 ATOM 6143 O O . SER B 1 359 ? 28.681 -13.561 20.842 1.00 28.03 ? 359 SER B O 1 ATOM 6144 C CB . SER B 1 359 ? 28.970 -10.676 21.984 1.00 27.67 ? 359 SER B CB 1 ATOM 6145 O OG . SER B 1 359 ? 28.743 -11.239 23.253 1.00 28.57 ? 359 SER B OG 1 ATOM 6146 N N . THR B 1 360 ? 30.514 -13.752 22.094 1.00 27.55 ? 360 THR B N 1 ATOM 6147 C CA . THR B 1 360 ? 30.325 -15.182 22.355 1.00 28.74 ? 360 THR B CA 1 ATOM 6148 C C . THR B 1 360 ? 29.479 -15.484 23.617 1.00 29.70 ? 360 THR B C 1 ATOM 6149 O O . THR B 1 360 ? 29.238 -16.646 23.965 1.00 30.54 ? 360 THR B O 1 ATOM 6150 C CB . THR B 1 360 ? 31.689 -15.870 22.500 1.00 29.69 ? 360 THR B CB 1 ATOM 6151 O OG1 . THR B 1 360 ? 32.300 -15.444 23.732 1.00 27.96 ? 360 THR B OG1 1 ATOM 6152 C CG2 . THR B 1 360 ? 32.636 -15.492 21.314 1.00 30.97 ? 360 THR B CG2 1 ATOM 6153 N N . THR B 1 361 ? 29.003 -14.435 24.282 1.00 31.14 ? 361 THR B N 1 ATOM 6154 C CA . THR B 1 361 ? 28.240 -14.530 25.552 1.00 32.33 ? 361 THR B CA 1 ATOM 6155 C C . THR B 1 361 ? 26.790 -14.007 25.433 1.00 32.61 ? 361 THR B C 1 ATOM 6156 O O . THR B 1 361 ? 25.849 -14.474 26.136 1.00 32.17 ? 361 THR B O 1 ATOM 6157 C CB . THR B 1 361 ? 28.958 -13.665 26.631 1.00 32.21 ? 361 THR B CB 1 ATOM 6158 O OG1 . THR B 1 361 ? 28.929 -12.287 26.202 1.00 31.18 ? 361 THR B OG1 1 ATOM 6159 C CG2 . THR B 1 361 ? 30.442 -14.130 26.824 1.00 32.47 ? 361 THR B CG2 1 ATOM 6160 N N . THR B 1 362 ? 26.628 -13.030 24.536 1.00 33.34 ? 362 THR B N 1 ATOM 6161 C CA . THR B 1 362 ? 25.397 -12.267 24.411 1.00 34.72 ? 362 THR B CA 1 ATOM 6162 C C . THR B 1 362 ? 24.908 -12.148 22.955 1.00 34.15 ? 362 THR B C 1 ATOM 6163 O O . THR B 1 362 ? 25.696 -11.868 22.059 1.00 33.69 ? 362 THR B O 1 ATOM 6164 C CB . THR B 1 362 ? 25.626 -10.822 24.931 1.00 35.77 ? 362 THR B CB 1 ATOM 6165 O OG1 . THR B 1 362 ? 26.512 -10.857 26.070 1.00 37.96 ? 362 THR B OG1 1 ATOM 6166 C CG2 . THR B 1 362 ? 24.261 -10.137 25.302 1.00 36.45 ? 362 THR B CG2 1 ATOM 6167 N N . VAL B 1 363 ? 23.609 -12.339 22.764 1.00 33.71 ? 363 VAL B N 1 ATOM 6168 C CA . VAL B 1 363 ? 22.910 -12.129 21.511 1.00 33.88 ? 363 VAL B CA 1 ATOM 6169 C C . VAL B 1 363 ? 23.110 -10.706 20.974 1.00 33.70 ? 363 VAL B C 1 ATOM 6170 O O . VAL B 1 363 ? 23.009 -9.703 21.719 1.00 32.78 ? 363 VAL B O 1 ATOM 6171 C CB . VAL B 1 363 ? 21.399 -12.360 21.681 1.00 34.46 ? 363 VAL B CB 1 ATOM 6172 C CG1 . VAL B 1 363 ? 20.650 -11.800 20.484 1.00 35.92 ? 363 VAL B CG1 1 ATOM 6173 C CG2 . VAL B 1 363 ? 21.110 -13.847 21.845 1.00 34.29 ? 363 VAL B CG2 1 ATOM 6174 N N . GLU B 1 364 ? 23.445 -10.640 19.687 1.00 32.73 ? 364 GLU B N 1 ATOM 6175 C CA . GLU B 1 364 ? 23.476 -9.372 18.976 1.00 32.99 ? 364 GLU B CA 1 ATOM 6176 C C . GLU B 1 364 ? 22.470 -9.390 17.829 1.00 32.50 ? 364 GLU B C 1 ATOM 6177 O O . GLU B 1 364 ? 22.512 -10.292 16.992 1.00 33.62 ? 364 GLU B O 1 ATOM 6178 C CB . GLU B 1 364 ? 24.879 -9.070 18.469 1.00 32.72 ? 364 GLU B CB 1 ATOM 6179 C CG . GLU B 1 364 ? 25.933 -9.057 19.583 1.00 33.94 ? 364 GLU B CG 1 ATOM 6180 C CD . GLU B 1 364 ? 27.329 -8.691 19.088 1.00 37.74 ? 364 GLU B CD 1 ATOM 6181 O OE1 . GLU B 1 364 ? 28.112 -8.151 19.905 1.00 41.11 ? 364 GLU B OE1 1 ATOM 6182 O OE2 . GLU B 1 364 ? 27.650 -8.916 17.902 1.00 35.11 ? 364 GLU B OE2 1 ATOM 6183 N N . ASN B 1 365 ? 21.564 -8.414 17.807 1.00 31.67 ? 365 ASN B N 1 ATOM 6184 C CA . ASN B 1 365 ? 20.655 -8.189 16.691 1.00 30.76 ? 365 ASN B CA 1 ATOM 6185 C C . ASN B 1 365 ? 21.367 -7.789 15.367 1.00 30.67 ? 365 ASN B C 1 ATOM 6186 O O . ASN B 1 365 ? 22.592 -7.601 15.300 1.00 29.65 ? 365 ASN B O 1 ATOM 6187 C CB . ASN B 1 365 ? 19.536 -7.201 17.088 1.00 30.16 ? 365 ASN B CB 1 ATOM 6188 C CG . ASN B 1 365 ? 20.036 -5.749 17.293 1.00 30.50 ? 365 ASN B CG 1 ATOM 6189 O OD1 . ASN B 1 365 ? 20.827 -5.222 16.507 1.00 30.05 ? 365 ASN B OD1 1 ATOM 6190 N ND2 . ASN B 1 365 ? 19.532 -5.086 18.352 1.00 30.05 ? 365 ASN B ND2 1 ATOM 6191 N N . ILE B 1 366 ? 20.561 -7.676 14.307 1.00 31.55 ? 366 ILE B N 1 ATOM 6192 C CA . ILE B 1 366 ? 21.074 -7.609 12.948 1.00 30.80 ? 366 ILE B CA 1 ATOM 6193 C C . ILE B 1 366 ? 21.656 -6.219 12.650 1.00 30.81 ? 366 ILE B C 1 ATOM 6194 O O . ILE B 1 366 ? 22.457 -6.073 11.732 1.00 30.79 ? 366 ILE B O 1 ATOM 6195 C CB . ILE B 1 366 ? 20.013 -8.161 11.906 1.00 30.85 ? 366 ILE B CB 1 ATOM 6196 C CG1 . ILE B 1 366 ? 20.661 -8.415 10.537 1.00 29.98 ? 366 ILE B CG1 1 ATOM 6197 C CG2 . ILE B 1 366 ? 18.848 -7.175 11.743 1.00 30.15 ? 366 ILE B CG2 1 ATOM 6198 C CD1 . ILE B 1 366 ? 21.544 -9.586 10.469 1.00 27.25 ? 366 ILE B CD1 1 ATOM 6199 N N . THR B 1 367 ? 21.300 -5.220 13.471 1.00 31.25 ? 367 THR B N 1 ATOM 6200 C CA . THR B 1 367 ? 21.939 -3.868 13.461 1.00 31.40 ? 367 THR B CA 1 ATOM 6201 C C . THR B 1 367 ? 23.345 -3.906 14.070 1.00 30.97 ? 367 THR B C 1 ATOM 6202 O O . THR B 1 367 ? 24.310 -3.420 13.484 1.00 30.27 ? 367 THR B O 1 ATOM 6203 C CB . THR B 1 367 ? 21.074 -2.821 14.243 1.00 32.26 ? 367 THR B CB 1 ATOM 6204 O OG1 . THR B 1 367 ? 19.768 -2.745 13.647 1.00 32.73 ? 367 THR B OG1 1 ATOM 6205 C CG2 . THR B 1 367 ? 21.700 -1.453 14.214 1.00 33.25 ? 367 THR B CG2 1 ATOM 6206 N N . GLN B 1 368 ? 23.447 -4.516 15.247 1.00 30.44 ? 368 GLN B N 1 ATOM 6207 C CA . GLN B 1 368 ? 24.738 -4.662 15.939 1.00 29.70 ? 368 GLN B CA 1 ATOM 6208 C C . GLN B 1 368 ? 25.731 -5.395 15.054 1.00 28.50 ? 368 GLN B C 1 ATOM 6209 O O . GLN B 1 368 ? 26.918 -5.022 15.029 1.00 27.22 ? 368 GLN B O 1 ATOM 6210 C CB . GLN B 1 368 ? 24.564 -5.371 17.292 1.00 29.76 ? 368 GLN B CB 1 ATOM 6211 C CG . GLN B 1 368 ? 23.384 -4.801 18.146 1.00 33.06 ? 368 GLN B CG 1 ATOM 6212 C CD . GLN B 1 368 ? 23.217 -5.486 19.488 1.00 34.86 ? 368 GLN B CD 1 ATOM 6213 O OE1 . GLN B 1 368 ? 22.357 -6.345 19.660 1.00 32.65 ? 368 GLN B OE1 1 ATOM 6214 N NE2 . GLN B 1 368 ? 24.067 -5.117 20.451 1.00 34.77 ? 368 GLN B NE2 1 ATOM 6215 N N . THR B 1 369 ? 25.249 -6.418 14.319 1.00 26.79 ? 369 THR B N 1 ATOM 6216 C CA . THR B 1 369 ? 26.166 -7.225 13.515 1.00 25.79 ? 369 THR B CA 1 ATOM 6217 C C . THR B 1 369 ? 26.369 -6.650 12.100 1.00 25.94 ? 369 THR B C 1 ATOM 6218 O O . THR B 1 369 ? 27.030 -7.277 11.238 1.00 25.12 ? 369 THR B O 1 ATOM 6219 C CB . THR B 1 369 ? 25.784 -8.717 13.432 1.00 25.44 ? 369 THR B CB 1 ATOM 6220 O OG1 . THR B 1 369 ? 24.488 -8.837 12.864 1.00 26.22 ? 369 THR B OG1 1 ATOM 6221 C CG2 . THR B 1 369 ? 25.820 -9.377 14.778 1.00 22.67 ? 369 THR B CG2 1 ATOM 6222 N N . ASP B 1 370 ? 25.795 -5.450 11.889 1.00 26.24 ? 370 ASP B N 1 ATOM 6223 C CA . ASP B 1 370 ? 25.798 -4.749 10.601 1.00 25.92 ? 370 ASP B CA 1 ATOM 6224 C C . ASP B 1 370 ? 25.432 -5.705 9.399 1.00 24.78 ? 370 ASP B C 1 ATOM 6225 O O . ASP B 1 370 ? 26.162 -5.781 8.441 1.00 24.64 ? 370 ASP B O 1 ATOM 6226 C CB . ASP B 1 370 ? 27.155 -4.057 10.396 1.00 25.53 ? 370 ASP B CB 1 ATOM 6227 C CG . ASP B 1 370 ? 27.156 -3.098 9.217 1.00 29.23 ? 370 ASP B CG 1 ATOM 6228 O OD1 . ASP B 1 370 ? 26.132 -2.398 9.060 1.00 32.87 ? 370 ASP B OD1 1 ATOM 6229 O OD2 . ASP B 1 370 ? 28.158 -3.034 8.452 1.00 29.46 ? 370 ASP B OD2 1 ATOM 6230 N N . GLY B 1 371 ? 24.324 -6.440 9.485 1.00 24.08 ? 371 GLY B N 1 ATOM 6231 C CA . GLY B 1 371 ? 23.814 -7.222 8.358 1.00 23.29 ? 371 GLY B CA 1 ATOM 6232 C C . GLY B 1 371 ? 24.256 -8.673 8.334 1.00 24.23 ? 371 GLY B C 1 ATOM 6233 O O . GLY B 1 371 ? 23.682 -9.498 7.576 1.00 24.49 ? 371 GLY B O 1 ATOM 6234 N N . PHE B 1 372 ? 25.244 -9.018 9.166 1.00 22.40 ? 372 PHE B N 1 ATOM 6235 C CA . PHE B 1 372 ? 25.645 -10.425 9.243 1.00 22.17 ? 372 PHE B CA 1 ATOM 6236 C C . PHE B 1 372 ? 24.812 -11.320 10.126 1.00 21.96 ? 372 PHE B C 1 ATOM 6237 O O . PHE B 1 372 ? 24.689 -11.090 11.303 1.00 21.62 ? 372 PHE B O 1 ATOM 6238 C CB . PHE B 1 372 ? 27.104 -10.662 9.665 1.00 21.14 ? 372 PHE B CB 1 ATOM 6239 C CG . PHE B 1 372 ? 27.445 -12.115 9.636 1.00 21.70 ? 372 PHE B CG 1 ATOM 6240 C CD1 . PHE B 1 372 ? 27.744 -12.723 8.417 1.00 19.96 ? 372 PHE B CD1 1 ATOM 6241 C CD2 . PHE B 1 372 ? 27.374 -12.904 10.803 1.00 17.62 ? 372 PHE B CD2 1 ATOM 6242 C CE1 . PHE B 1 372 ? 27.979 -14.088 8.330 1.00 19.52 ? 372 PHE B CE1 1 ATOM 6243 C CE2 . PHE B 1 372 ? 27.636 -14.253 10.756 1.00 18.42 ? 372 PHE B CE2 1 ATOM 6244 C CZ . PHE B 1 372 ? 27.950 -14.873 9.521 1.00 19.58 ? 372 PHE B CZ 1 ATOM 6245 N N . SER B 1 373 ? 24.295 -12.387 9.544 1.00 22.29 ? 373 SER B N 1 ATOM 6246 C CA . SER B 1 373 ? 23.787 -13.517 10.275 1.00 22.00 ? 373 SER B CA 1 ATOM 6247 C C . SER B 1 373 ? 23.812 -14.709 9.298 1.00 21.69 ? 373 SER B C 1 ATOM 6248 O O . SER B 1 373 ? 23.942 -14.493 8.097 1.00 21.66 ? 373 SER B O 1 ATOM 6249 C CB . SER B 1 373 ? 22.362 -13.245 10.775 1.00 22.98 ? 373 SER B CB 1 ATOM 6250 O OG . SER B 1 373 ? 21.396 -13.354 9.754 1.00 22.66 ? 373 SER B OG 1 ATOM 6251 N N . SER B 1 374 ? 23.712 -15.936 9.806 1.00 20.59 ? 374 SER B N 1 ATOM 6252 C CA . SER B 1 374 ? 23.683 -17.105 8.964 1.00 21.50 ? 374 SER B CA 1 ATOM 6253 C C . SER B 1 374 ? 22.471 -17.069 8.060 1.00 21.25 ? 374 SER B C 1 ATOM 6254 O O . SER B 1 374 ? 22.573 -17.310 6.868 1.00 21.33 ? 374 SER B O 1 ATOM 6255 C CB . SER B 1 374 ? 23.589 -18.372 9.796 1.00 21.53 ? 374 SER B CB 1 ATOM 6256 O OG . SER B 1 374 ? 24.863 -18.769 10.133 1.00 26.39 ? 374 SER B OG 1 ATOM 6257 N N . ALA B 1 375 ? 21.318 -16.825 8.679 1.00 20.93 ? 375 ALA B N 1 ATOM 6258 C CA . ALA B 1 375 ? 20.024 -16.716 8.032 1.00 20.69 ? 375 ALA B CA 1 ATOM 6259 C C . ALA B 1 375 ? 19.980 -15.637 6.885 1.00 19.81 ? 375 ALA B C 1 ATOM 6260 O O . ALA B 1 375 ? 19.344 -15.852 5.840 1.00 20.99 ? 375 ALA B O 1 ATOM 6261 C CB . ALA B 1 375 ? 18.866 -16.509 9.131 1.00 18.82 ? 375 ALA B CB 1 ATOM 6262 N N . TRP B 1 376 ? 20.705 -14.552 7.055 1.00 17.11 ? 376 TRP B N 1 ATOM 6263 C CA . TRP B 1 376 ? 20.756 -13.504 6.069 1.00 17.32 ? 376 TRP B CA 1 ATOM 6264 C C . TRP B 1 376 ? 21.830 -13.694 4.978 1.00 17.52 ? 376 TRP B C 1 ATOM 6265 O O . TRP B 1 376 ? 21.849 -12.919 3.997 1.00 18.15 ? 376 TRP B O 1 ATOM 6266 C CB . TRP B 1 376 ? 21.042 -12.157 6.776 1.00 16.42 ? 376 TRP B CB 1 ATOM 6267 C CG . TRP B 1 376 ? 19.824 -11.570 7.404 1.00 14.74 ? 376 TRP B CG 1 ATOM 6268 C CD1 . TRP B 1 376 ? 18.824 -12.246 8.030 1.00 16.11 ? 376 TRP B CD1 1 ATOM 6269 C CD2 . TRP B 1 376 ? 19.466 -10.186 7.450 1.00 12.72 ? 376 TRP B CD2 1 ATOM 6270 N NE1 . TRP B 1 376 ? 17.863 -11.386 8.434 1.00 14.66 ? 376 TRP B NE1 1 ATOM 6271 C CE2 . TRP B 1 376 ? 18.229 -10.109 8.103 1.00 14.14 ? 376 TRP B CE2 1 ATOM 6272 C CE3 . TRP B 1 376 ? 20.058 -9.010 6.957 1.00 13.36 ? 376 TRP B CE3 1 ATOM 6273 C CZ2 . TRP B 1 376 ? 17.553 -8.905 8.288 1.00 14.87 ? 376 TRP B CZ2 1 ATOM 6274 C CZ3 . TRP B 1 376 ? 19.417 -7.804 7.149 1.00 15.30 ? 376 TRP B CZ3 1 ATOM 6275 C CH2 . TRP B 1 376 ? 18.172 -7.751 7.820 1.00 15.82 ? 376 TRP B CH2 1 ATOM 6276 N N . THR B 1 377 ? 22.727 -14.671 5.135 1.00 15.76 ? 377 THR B N 1 ATOM 6277 C CA . THR B 1 377 ? 23.814 -14.832 4.191 1.00 15.27 ? 377 THR B CA 1 ATOM 6278 C C . THR B 1 377 ? 23.763 -16.221 3.532 1.00 15.05 ? 377 THR B C 1 ATOM 6279 O O . THR B 1 377 ? 23.919 -16.323 2.331 1.00 15.16 ? 377 THR B O 1 ATOM 6280 C CB . THR B 1 377 ? 25.182 -14.646 4.862 1.00 14.80 ? 377 THR B CB 1 ATOM 6281 O OG1 . THR B 1 377 ? 25.236 -15.535 5.968 1.00 17.16 ? 377 THR B OG1 1 ATOM 6282 C CG2 . THR B 1 377 ? 25.337 -13.272 5.415 1.00 18.17 ? 377 THR B CG2 1 ATOM 6283 N N . VAL B 1 378 ? 23.591 -17.297 4.312 1.00 15.18 ? 378 VAL B N 1 ATOM 6284 C CA . VAL B 1 378 ? 23.615 -18.646 3.750 1.00 14.74 ? 378 VAL B CA 1 ATOM 6285 C C . VAL B 1 378 ? 22.464 -19.513 4.207 1.00 15.54 ? 378 VAL B C 1 ATOM 6286 O O . VAL B 1 378 ? 22.700 -20.640 4.709 1.00 16.66 ? 378 VAL B O 1 ATOM 6287 C CB . VAL B 1 378 ? 24.957 -19.341 4.020 1.00 16.70 ? 378 VAL B CB 1 ATOM 6288 C CG1 . VAL B 1 378 ? 26.020 -18.466 3.497 1.00 14.60 ? 378 VAL B CG1 1 ATOM 6289 C CG2 . VAL B 1 378 ? 25.189 -19.629 5.603 1.00 14.05 ? 378 VAL B CG2 1 ATOM 6290 N N . PRO B 1 379 ? 21.221 -19.044 3.991 1.00 15.55 ? 379 PRO B N 1 ATOM 6291 C CA . PRO B 1 379 ? 20.113 -19.929 4.208 1.00 16.37 ? 379 PRO B CA 1 ATOM 6292 C C . PRO B 1 379 ? 20.120 -20.969 3.106 1.00 16.81 ? 379 PRO B C 1 ATOM 6293 O O . PRO B 1 379 ? 20.953 -20.911 2.196 1.00 18.24 ? 379 PRO B O 1 ATOM 6294 C CB . PRO B 1 379 ? 18.912 -19.028 4.015 1.00 16.83 ? 379 PRO B CB 1 ATOM 6295 C CG . PRO B 1 379 ? 19.363 -18.036 2.996 1.00 15.92 ? 379 PRO B CG 1 ATOM 6296 C CD . PRO B 1 379 ? 20.777 -17.753 3.402 1.00 16.10 ? 379 PRO B CD 1 ATOM 6297 N N . PHE B 1 380 ? 19.257 -21.956 3.212 1.00 17.04 ? 380 PHE B N 1 ATOM 6298 C CA . PHE B 1 380 ? 19.103 -22.918 2.137 1.00 17.07 ? 380 PHE B CA 1 ATOM 6299 C C . PHE B 1 380 ? 18.787 -22.072 0.875 1.00 16.71 ? 380 PHE B C 1 ATOM 6300 O O . PHE B 1 380 ? 17.987 -21.102 0.945 1.00 16.15 ? 380 PHE B O 1 ATOM 6301 C CB . PHE B 1 380 ? 17.933 -23.847 2.437 1.00 16.57 ? 380 PHE B CB 1 ATOM 6302 C CG . PHE B 1 380 ? 18.228 -24.908 3.471 1.00 18.32 ? 380 PHE B CG 1 ATOM 6303 C CD1 . PHE B 1 380 ? 19.380 -25.699 3.384 1.00 17.17 ? 380 PHE B CD1 1 ATOM 6304 C CD2 . PHE B 1 380 ? 17.311 -25.162 4.483 1.00 15.77 ? 380 PHE B CD2 1 ATOM 6305 C CE1 . PHE B 1 380 ? 19.644 -26.713 4.314 1.00 18.76 ? 380 PHE B CE1 1 ATOM 6306 C CE2 . PHE B 1 380 ? 17.566 -26.161 5.411 1.00 21.12 ? 380 PHE B CE2 1 ATOM 6307 C CZ . PHE B 1 380 ? 18.735 -26.947 5.334 1.00 18.44 ? 380 PHE B CZ 1 ATOM 6308 N N . ALA B 1 381 ? 19.391 -22.469 -0.250 1.00 16.28 ? 381 ALA B N 1 ATOM 6309 C CA . ALA B 1 381 ? 19.193 -21.831 -1.565 1.00 16.36 ? 381 ALA B CA 1 ATOM 6310 C C . ALA B 1 381 ? 19.636 -20.361 -1.548 1.00 16.15 ? 381 ALA B C 1 ATOM 6311 O O . ALA B 1 381 ? 19.119 -19.580 -2.321 1.00 16.85 ? 381 ALA B O 1 ATOM 6312 C CB . ALA B 1 381 ? 17.740 -21.929 -1.992 1.00 15.84 ? 381 ALA B CB 1 ATOM 6313 N N . SER B 1 382 ? 20.551 -19.983 -0.660 1.00 15.42 ? 382 SER B N 1 ATOM 6314 C CA . SER B 1 382 ? 21.047 -18.623 -0.623 1.00 16.60 ? 382 SER B CA 1 ATOM 6315 C C . SER B 1 382 ? 21.606 -18.246 -1.982 1.00 16.82 ? 382 SER B C 1 ATOM 6316 O O . SER B 1 382 ? 22.077 -19.109 -2.742 1.00 17.28 ? 382 SER B O 1 ATOM 6317 C CB . SER B 1 382 ? 22.233 -18.475 0.361 1.00 16.63 ? 382 SER B CB 1 ATOM 6318 O OG . SER B 1 382 ? 23.354 -19.287 -0.034 1.00 18.53 ? 382 SER B OG 1 ATOM 6319 N N . ARG B 1 383 ? 21.625 -16.946 -2.249 1.00 17.79 ? 383 ARG B N 1 ATOM 6320 C CA . ARG B 1 383 ? 22.274 -16.418 -3.454 1.00 17.31 ? 383 ARG B CA 1 ATOM 6321 C C . ARG B 1 383 ? 22.987 -15.101 -3.185 1.00 17.12 ? 383 ARG B C 1 ATOM 6322 O O . ARG B 1 383 ? 22.547 -14.279 -2.362 1.00 16.21 ? 383 ARG B O 1 ATOM 6323 C CB . ARG B 1 383 ? 21.332 -16.407 -4.705 1.00 16.76 ? 383 ARG B CB 1 ATOM 6324 C CG . ARG B 1 383 ? 20.157 -15.476 -4.673 1.00 17.29 ? 383 ARG B CG 1 ATOM 6325 C CD . ARG B 1 383 ? 19.177 -15.664 -3.480 1.00 17.53 ? 383 ARG B CD 1 ATOM 6326 N NE . ARG B 1 383 ? 18.443 -16.948 -3.490 1.00 18.76 ? 383 ARG B NE 1 ATOM 6327 C CZ . ARG B 1 383 ? 17.295 -17.141 -4.113 1.00 17.59 ? 383 ARG B CZ 1 ATOM 6328 N NH1 . ARG B 1 383 ? 16.766 -16.159 -4.832 1.00 20.45 ? 383 ARG B NH1 1 ATOM 6329 N NH2 . ARG B 1 383 ? 16.704 -18.308 -4.067 1.00 17.97 ? 383 ARG B NH2 1 ATOM 6330 N N . LEU B 1 384 ? 24.156 -15.008 -3.829 1.00 15.82 ? 384 LEU B N 1 ATOM 6331 C CA . LEU B 1 384 ? 24.949 -13.823 -3.948 1.00 16.97 ? 384 LEU B CA 1 ATOM 6332 C C . LEU B 1 384 ? 25.022 -13.402 -5.461 1.00 17.01 ? 384 LEU B C 1 ATOM 6333 O O . LEU B 1 384 ? 25.444 -14.203 -6.331 1.00 17.46 ? 384 LEU B O 1 ATOM 6334 C CB . LEU B 1 384 ? 26.393 -14.155 -3.468 1.00 17.08 ? 384 LEU B CB 1 ATOM 6335 C CG . LEU B 1 384 ? 27.485 -13.129 -3.747 1.00 19.81 ? 384 LEU B CG 1 ATOM 6336 C CD1 . LEU B 1 384 ? 27.346 -11.827 -2.842 1.00 19.41 ? 384 LEU B CD1 1 ATOM 6337 C CD2 . LEU B 1 384 ? 28.896 -13.734 -3.740 1.00 19.48 ? 384 LEU B CD2 1 ATOM 6338 N N . TYR B 1 385 ? 24.642 -12.172 -5.774 1.00 16.91 ? 385 TYR B N 1 ATOM 6339 C CA . TYR B 1 385 ? 24.811 -11.642 -7.125 1.00 16.92 ? 385 TYR B CA 1 ATOM 6340 C C . TYR B 1 385 ? 25.915 -10.593 -7.102 1.00 17.46 ? 385 TYR B C 1 ATOM 6341 O O . TYR B 1 385 ? 25.857 -9.619 -6.283 1.00 16.82 ? 385 TYR B O 1 ATOM 6342 C CB . TYR B 1 385 ? 23.563 -10.923 -7.621 1.00 15.74 ? 385 TYR B CB 1 ATOM 6343 C CG . TYR B 1 385 ? 22.265 -11.714 -7.648 1.00 17.95 ? 385 TYR B CG 1 ATOM 6344 C CD1 . TYR B 1 385 ? 22.245 -13.088 -7.951 1.00 14.07 ? 385 TYR B CD1 1 ATOM 6345 C CD2 . TYR B 1 385 ? 21.029 -11.073 -7.409 1.00 14.86 ? 385 TYR B CD2 1 ATOM 6346 C CE1 . TYR B 1 385 ? 21.054 -13.785 -7.993 1.00 13.57 ? 385 TYR B CE1 1 ATOM 6347 C CE2 . TYR B 1 385 ? 19.839 -11.790 -7.453 1.00 17.77 ? 385 TYR B CE2 1 ATOM 6348 C CZ . TYR B 1 385 ? 19.864 -13.151 -7.758 1.00 17.35 ? 385 TYR B CZ 1 ATOM 6349 O OH . TYR B 1 385 ? 18.688 -13.896 -7.800 1.00 17.61 ? 385 TYR B OH 1 ATOM 6350 N N . VAL B 1 386 ? 26.886 -10.769 -7.995 1.00 16.39 ? 386 VAL B N 1 ATOM 6351 C CA . VAL B 1 386 ? 27.822 -9.712 -8.280 1.00 16.64 ? 386 VAL B CA 1 ATOM 6352 C C . VAL B 1 386 ? 27.543 -9.090 -9.687 1.00 17.83 ? 386 VAL B C 1 ATOM 6353 O O . VAL B 1 386 ? 27.597 -9.781 -10.709 1.00 18.72 ? 386 VAL B O 1 ATOM 6354 C CB . VAL B 1 386 ? 29.255 -10.239 -8.218 1.00 16.52 ? 386 VAL B CB 1 ATOM 6355 C CG1 . VAL B 1 386 ? 30.269 -9.151 -8.528 1.00 15.55 ? 386 VAL B CG1 1 ATOM 6356 C CG2 . VAL B 1 386 ? 29.554 -10.953 -6.846 1.00 15.72 ? 386 VAL B CG2 1 ATOM 6357 N N . GLU B 1 387 ? 27.205 -7.812 -9.714 1.00 18.10 ? 387 GLU B N 1 ATOM 6358 C CA . GLU B 1 387 ? 26.950 -7.046 -10.936 1.00 18.31 ? 387 GLU B CA 1 ATOM 6359 C C . GLU B 1 387 ? 28.041 -6.093 -11.216 1.00 19.26 ? 387 GLU B C 1 ATOM 6360 O O . GLU B 1 387 ? 28.669 -5.520 -10.316 1.00 19.93 ? 387 GLU B O 1 ATOM 6361 C CB . GLU B 1 387 ? 25.682 -6.201 -10.824 1.00 17.01 ? 387 GLU B CB 1 ATOM 6362 C CG . GLU B 1 387 ? 24.498 -7.016 -10.538 1.00 17.93 ? 387 GLU B CG 1 ATOM 6363 C CD . GLU B 1 387 ? 23.329 -6.201 -10.085 1.00 19.92 ? 387 GLU B CD 1 ATOM 6364 O OE1 . GLU B 1 387 ? 22.219 -6.757 -10.015 1.00 20.14 ? 387 GLU B OE1 1 ATOM 6365 O OE2 . GLU B 1 387 ? 23.531 -5.014 -9.776 1.00 22.55 ? 387 GLU B OE2 1 ATOM 6366 N N . MET B 1 388 ? 28.240 -5.898 -12.502 1.00 20.35 ? 388 MET B N 1 ATOM 6367 C CA . MET B 1 388 ? 29.018 -4.811 -13.034 1.00 21.80 ? 388 MET B CA 1 ATOM 6368 C C . MET B 1 388 ? 28.016 -4.051 -13.937 1.00 22.53 ? 388 MET B C 1 ATOM 6369 O O . MET B 1 388 ? 27.156 -4.648 -14.571 1.00 22.28 ? 388 MET B O 1 ATOM 6370 C CB . MET B 1 388 ? 30.176 -5.423 -13.780 1.00 21.46 ? 388 MET B CB 1 ATOM 6371 C CG . MET B 1 388 ? 31.328 -4.555 -13.967 1.00 25.82 ? 388 MET B CG 1 ATOM 6372 S SD . MET B 1 388 ? 32.934 -5.384 -14.005 1.00 28.71 ? 388 MET B SD 1 ATOM 6373 C CE . MET B 1 388 ? 32.800 -6.618 -15.294 1.00 27.61 ? 388 MET B CE 1 ATOM 6374 N N . MET B 1 389 ? 28.097 -2.741 -13.965 1.00 23.50 ? 389 MET B N 1 ATOM 6375 C CA . MET B 1 389 ? 27.147 -1.938 -14.704 1.00 24.23 ? 389 MET B CA 1 ATOM 6376 C C . MET B 1 389 ? 27.883 -0.776 -15.253 1.00 26.73 ? 389 MET B C 1 ATOM 6377 O O . MET B 1 389 ? 28.924 -0.393 -14.730 1.00 26.95 ? 389 MET B O 1 ATOM 6378 C CB . MET B 1 389 ? 25.981 -1.435 -13.828 1.00 22.80 ? 389 MET B CB 1 ATOM 6379 C CG . MET B 1 389 ? 26.290 -0.352 -12.754 1.00 19.70 ? 389 MET B CG 1 ATOM 6380 S SD . MET B 1 389 ? 24.787 -0.007 -11.717 1.00 23.57 ? 389 MET B SD 1 ATOM 6381 C CE . MET B 1 389 ? 24.557 -1.581 -10.865 1.00 24.36 ? 389 MET B CE 1 ATOM 6382 N N . GLN B 1 390 ? 27.322 -0.200 -16.300 1.00 29.94 ? 390 GLN B N 1 ATOM 6383 C CA . GLN B 1 390 ? 27.933 0.920 -16.992 1.00 33.85 ? 390 GLN B CA 1 ATOM 6384 C C . GLN B 1 390 ? 26.955 2.059 -16.935 1.00 34.86 ? 390 GLN B C 1 ATOM 6385 O O . GLN B 1 390 ? 25.766 1.886 -17.207 1.00 35.60 ? 390 GLN B O 1 ATOM 6386 C CB . GLN B 1 390 ? 28.232 0.512 -18.435 1.00 34.34 ? 390 GLN B CB 1 ATOM 6387 C CG . GLN B 1 390 ? 29.159 1.436 -19.115 1.00 37.51 ? 390 GLN B CG 1 ATOM 6388 C CD . GLN B 1 390 ? 30.597 1.245 -18.719 1.00 40.90 ? 390 GLN B CD 1 ATOM 6389 O OE1 . GLN B 1 390 ? 31.337 2.223 -18.647 1.00 44.59 ? 390 GLN B OE1 1 ATOM 6390 N NE2 . GLN B 1 390 ? 31.020 -0.006 -18.482 1.00 39.70 ? 390 GLN B NE2 1 ATOM 6391 N N . CYS B 1 391 ? 27.424 3.206 -16.501 1.00 37.60 ? 391 CYS B N 1 ATOM 6392 C CA . CYS B 1 391 ? 26.497 4.298 -16.298 1.00 40.58 ? 391 CYS B CA 1 ATOM 6393 C C . CYS B 1 391 ? 26.845 5.510 -17.126 1.00 43.27 ? 391 CYS B C 1 ATOM 6394 O O . CYS B 1 391 ? 27.945 5.589 -17.711 1.00 43.06 ? 391 CYS B O 1 ATOM 6395 C CB . CYS B 1 391 ? 26.327 4.651 -14.830 1.00 40.20 ? 391 CYS B CB 1 ATOM 6396 S SG . CYS B 1 391 ? 25.799 3.258 -13.871 1.00 37.68 ? 391 CYS B SG 1 ATOM 6397 N N . GLN B 1 392 ? 25.857 6.416 -17.198 1.00 46.92 ? 392 GLN B N 1 ATOM 6398 C CA . GLN B 1 392 ? 25.916 7.644 -18.006 1.00 49.95 ? 392 GLN B CA 1 ATOM 6399 C C . GLN B 1 392 ? 27.130 8.506 -17.655 1.00 50.98 ? 392 GLN B C 1 ATOM 6400 O O . GLN B 1 392 ? 28.011 8.733 -18.525 1.00 51.73 ? 392 GLN B O 1 ATOM 6401 C CB . GLN B 1 392 ? 24.620 8.464 -17.876 1.00 50.38 ? 392 GLN B CB 1 ATOM 6402 C CG . GLN B 1 392 ? 24.352 9.320 -19.141 1.00 55.83 ? 392 GLN B CG 1 ATOM 6403 C CD . GLN B 1 392 ? 22.914 9.195 -19.702 1.00 62.34 ? 392 GLN B CD 1 ATOM 6404 O OE1 . GLN B 1 392 ? 22.127 8.322 -19.282 1.00 65.15 ? 392 GLN B OE1 1 ATOM 6405 N NE2 . GLN B 1 392 ? 22.571 10.077 -20.663 1.00 64.13 ? 392 GLN B NE2 1 ATOM 6406 N N . ALA B 1 393 ? 27.184 8.950 -16.394 1.00 51.61 ? 393 ALA B N 1 ATOM 6407 C CA . ALA B 1 393 ? 28.169 9.961 -15.973 1.00 52.25 ? 393 ALA B CA 1 ATOM 6408 C C . ALA B 1 393 ? 29.604 9.436 -15.675 1.00 52.28 ? 393 ALA B C 1 ATOM 6409 O O . ALA B 1 393 ? 30.501 10.231 -15.329 1.00 52.78 ? 393 ALA B O 1 ATOM 6410 C CB . ALA B 1 393 ? 27.601 10.825 -14.780 1.00 52.46 ? 393 ALA B CB 1 ATOM 6411 N N . GLU B 1 394 ? 29.816 8.119 -15.827 1.00 51.45 ? 394 GLU B N 1 ATOM 6412 C CA . GLU B 1 394 ? 31.070 7.457 -15.419 1.00 50.20 ? 394 GLU B CA 1 ATOM 6413 C C . GLU B 1 394 ? 31.655 6.574 -16.553 1.00 49.17 ? 394 GLU B C 1 ATOM 6414 O O . GLU B 1 394 ? 30.936 5.820 -17.197 1.00 49.16 ? 394 GLU B O 1 ATOM 6415 C CB . GLU B 1 394 ? 30.829 6.687 -14.101 1.00 50.18 ? 394 GLU B CB 1 ATOM 6416 C CG . GLU B 1 394 ? 31.998 5.847 -13.548 1.00 51.53 ? 394 GLU B CG 1 ATOM 6417 C CD . GLU B 1 394 ? 33.204 6.657 -13.043 1.00 53.85 ? 394 GLU B CD 1 ATOM 6418 O OE1 . GLU B 1 394 ? 33.075 7.404 -12.034 1.00 52.70 ? 394 GLU B OE1 1 ATOM 6419 O OE2 . GLU B 1 394 ? 34.297 6.502 -13.650 1.00 54.19 ? 394 GLU B OE2 1 ATOM 6420 N N . GLN B 1 395 ? 32.953 6.694 -16.809 1.00 47.49 ? 395 GLN B N 1 ATOM 6421 C CA . GLN B 1 395 ? 33.582 5.925 -17.882 1.00 46.31 ? 395 GLN B CA 1 ATOM 6422 C C . GLN B 1 395 ? 33.881 4.529 -17.421 1.00 44.47 ? 395 GLN B C 1 ATOM 6423 O O . GLN B 1 395 ? 33.960 3.618 -18.236 1.00 44.96 ? 395 GLN B O 1 ATOM 6424 C CB . GLN B 1 395 ? 34.889 6.562 -18.357 1.00 47.08 ? 395 GLN B CB 1 ATOM 6425 C CG . GLN B 1 395 ? 34.730 8.021 -18.813 1.00 53.07 ? 395 GLN B CG 1 ATOM 6426 C CD . GLN B 1 395 ? 35.316 9.048 -17.810 1.00 60.21 ? 395 GLN B CD 1 ATOM 6427 O OE1 . GLN B 1 395 ? 36.243 9.815 -18.158 1.00 63.64 ? 395 GLN B OE1 1 ATOM 6428 N NE2 . GLN B 1 395 ? 34.789 9.062 -16.569 1.00 59.82 ? 395 GLN B NE2 1 ATOM 6429 N N . GLU B 1 396 ? 34.063 4.354 -16.115 1.00 41.24 ? 396 GLU B N 1 ATOM 6430 C CA . GLU B 1 396 ? 34.411 3.046 -15.579 1.00 38.48 ? 396 GLU B CA 1 ATOM 6431 C C . GLU B 1 396 ? 33.219 2.179 -15.204 1.00 34.66 ? 396 GLU B C 1 ATOM 6432 O O . GLU B 1 396 ? 32.172 2.689 -14.797 1.00 34.57 ? 396 GLU B O 1 ATOM 6433 C CB . GLU B 1 396 ? 35.295 3.207 -14.352 1.00 39.56 ? 396 GLU B CB 1 ATOM 6434 C CG . GLU B 1 396 ? 36.790 3.338 -14.673 1.00 43.96 ? 396 GLU B CG 1 ATOM 6435 C CD . GLU B 1 396 ? 37.623 3.034 -13.430 1.00 51.15 ? 396 GLU B CD 1 ATOM 6436 O OE1 . GLU B 1 396 ? 37.678 1.803 -13.056 1.00 52.82 ? 396 GLU B OE1 1 ATOM 6437 O OE2 . GLU B 1 396 ? 38.164 4.016 -12.827 1.00 49.23 ? 396 GLU B OE2 1 ATOM 6438 N N . PRO B 1 397 ? 33.395 0.857 -15.294 1.00 30.98 ? 397 PRO B N 1 ATOM 6439 C CA . PRO B 1 397 ? 32.330 0.009 -14.795 1.00 28.58 ? 397 PRO B CA 1 ATOM 6440 C C . PRO B 1 397 ? 32.240 0.128 -13.272 1.00 26.41 ? 397 PRO B C 1 ATOM 6441 O O . PRO B 1 397 ? 33.232 0.280 -12.612 1.00 25.66 ? 397 PRO B O 1 ATOM 6442 C CB . PRO B 1 397 ? 32.773 -1.397 -15.211 1.00 28.12 ? 397 PRO B CB 1 ATOM 6443 C CG . PRO B 1 397 ? 34.065 -1.218 -15.997 1.00 28.00 ? 397 PRO B CG 1 ATOM 6444 C CD . PRO B 1 397 ? 34.604 0.091 -15.631 1.00 30.11 ? 397 PRO B CD 1 ATOM 6445 N N . LEU B 1 398 ? 31.042 0.049 -12.753 1.00 25.28 ? 398 LEU B N 1 ATOM 6446 C CA . LEU B 1 398 ? 30.754 0.082 -11.337 1.00 23.95 ? 398 LEU B CA 1 ATOM 6447 C C . LEU B 1 398 ? 30.281 -1.305 -10.867 1.00 23.67 ? 398 LEU B C 1 ATOM 6448 O O . LEU B 1 398 ? 29.346 -1.892 -11.461 1.00 23.59 ? 398 LEU B O 1 ATOM 6449 C CB . LEU B 1 398 ? 29.663 1.111 -11.078 1.00 23.47 ? 398 LEU B CB 1 ATOM 6450 C CG . LEU B 1 398 ? 29.950 2.585 -11.375 1.00 24.50 ? 398 LEU B CG 1 ATOM 6451 C CD1 . LEU B 1 398 ? 28.810 3.422 -10.818 1.00 24.14 ? 398 LEU B CD1 1 ATOM 6452 C CD2 . LEU B 1 398 ? 31.267 3.029 -10.796 1.00 21.87 ? 398 LEU B CD2 1 ATOM 6453 N N . VAL B 1 399 ? 30.922 -1.829 -9.810 1.00 22.50 ? 399 VAL B N 1 ATOM 6454 C CA . VAL B 1 399 ? 30.589 -3.159 -9.218 1.00 20.03 ? 399 VAL B CA 1 ATOM 6455 C C . VAL B 1 399 ? 29.508 -3.010 -8.151 1.00 19.91 ? 399 VAL B C 1 ATOM 6456 O O . VAL B 1 399 ? 29.490 -2.054 -7.354 1.00 21.22 ? 399 VAL B O 1 ATOM 6457 C CB . VAL B 1 399 ? 31.811 -3.701 -8.565 1.00 20.09 ? 399 VAL B CB 1 ATOM 6458 C CG1 . VAL B 1 399 ? 31.549 -5.028 -7.889 1.00 19.20 ? 399 VAL B CG1 1 ATOM 6459 C CG2 . VAL B 1 399 ? 32.960 -3.796 -9.577 1.00 18.57 ? 399 VAL B CG2 1 ATOM 6460 N N . ARG B 1 400 ? 28.567 -3.911 -8.111 1.00 19.02 ? 400 ARG B N 1 ATOM 6461 C CA . ARG B 1 400 ? 27.584 -3.868 -7.054 1.00 17.66 ? 400 ARG B CA 1 ATOM 6462 C C . ARG B 1 400 ? 27.334 -5.300 -6.608 1.00 18.93 ? 400 ARG B C 1 ATOM 6463 O O . ARG B 1 400 ? 27.392 -6.238 -7.441 1.00 18.06 ? 400 ARG B O 1 ATOM 6464 C CB . ARG B 1 400 ? 26.313 -3.249 -7.559 1.00 18.12 ? 400 ARG B CB 1 ATOM 6465 C CG . ARG B 1 400 ? 25.112 -3.280 -6.568 1.00 20.03 ? 400 ARG B CG 1 ATOM 6466 C CD . ARG B 1 400 ? 23.962 -2.371 -6.981 1.00 24.96 ? 400 ARG B CD 1 ATOM 6467 N NE . ARG B 1 400 ? 23.115 -3.072 -7.918 1.00 29.61 ? 400 ARG B NE 1 ATOM 6468 C CZ . ARG B 1 400 ? 21.836 -2.794 -8.180 1.00 30.60 ? 400 ARG B CZ 1 ATOM 6469 N NH1 . ARG B 1 400 ? 21.217 -1.802 -7.546 1.00 26.96 ? 400 ARG B NH1 1 ATOM 6470 N NH2 . ARG B 1 400 ? 21.180 -3.542 -9.086 1.00 27.45 ? 400 ARG B NH2 1 ATOM 6471 N N . VAL B 1 401 ? 27.036 -5.483 -5.317 1.00 19.27 ? 401 VAL B N 1 ATOM 6472 C CA . VAL B 1 401 ? 26.832 -6.810 -4.750 1.00 19.72 ? 401 VAL B CA 1 ATOM 6473 C C . VAL B 1 401 ? 25.485 -6.959 -4.041 1.00 20.26 ? 401 VAL B C 1 ATOM 6474 O O . VAL B 1 401 ? 25.110 -6.103 -3.250 1.00 21.15 ? 401 VAL B O 1 ATOM 6475 C CB . VAL B 1 401 ? 28.015 -7.203 -3.817 1.00 20.68 ? 401 VAL B CB 1 ATOM 6476 C CG1 . VAL B 1 401 ? 27.642 -8.405 -2.997 1.00 19.52 ? 401 VAL B CG1 1 ATOM 6477 C CG2 . VAL B 1 401 ? 29.266 -7.524 -4.642 1.00 17.90 ? 401 VAL B CG2 1 ATOM 6478 N N . LEU B 1 402 ? 24.726 -8.016 -4.354 1.00 19.16 ? 402 LEU B N 1 ATOM 6479 C CA . LEU B 1 402 ? 23.529 -8.305 -3.556 1.00 18.32 ? 402 LEU B CA 1 ATOM 6480 C C . LEU B 1 402 ? 23.645 -9.665 -2.853 1.00 18.34 ? 402 LEU B C 1 ATOM 6481 O O . LEU B 1 402 ? 24.047 -10.665 -3.485 1.00 19.39 ? 402 LEU B O 1 ATOM 6482 C CB . LEU B 1 402 ? 22.247 -8.266 -4.410 1.00 17.82 ? 402 LEU B CB 1 ATOM 6483 C CG . LEU B 1 402 ? 21.963 -6.899 -5.116 1.00 17.65 ? 402 LEU B CG 1 ATOM 6484 C CD1 . LEU B 1 402 ? 22.708 -6.781 -6.370 1.00 11.32 ? 402 LEU B CD1 1 ATOM 6485 C CD2 . LEU B 1 402 ? 20.521 -6.794 -5.419 1.00 17.63 ? 402 LEU B CD2 1 ATOM 6486 N N . VAL B 1 403 ? 23.272 -9.702 -1.576 1.00 17.43 ? 403 VAL B N 1 ATOM 6487 C CA . VAL B 1 403 ? 23.264 -10.922 -0.765 1.00 16.46 ? 403 VAL B CA 1 ATOM 6488 C C . VAL B 1 403 ? 21.819 -11.193 -0.353 1.00 17.32 ? 403 VAL B C 1 ATOM 6489 O O . VAL B 1 403 ? 21.207 -10.473 0.475 1.00 16.31 ? 403 VAL B O 1 ATOM 6490 C CB . VAL B 1 403 ? 24.193 -10.821 0.494 1.00 15.77 ? 403 VAL B CB 1 ATOM 6491 C CG1 . VAL B 1 403 ? 24.099 -12.098 1.363 1.00 16.26 ? 403 VAL B CG1 1 ATOM 6492 C CG2 . VAL B 1 403 ? 25.660 -10.515 0.085 1.00 14.63 ? 403 VAL B CG2 1 ATOM 6493 N N . ASN B 1 404 ? 21.270 -12.228 -0.983 1.00 17.70 ? 404 ASN B N 1 ATOM 6494 C CA . ASN B 1 404 ? 19.880 -12.577 -0.794 1.00 18.07 ? 404 ASN B CA 1 ATOM 6495 C C . ASN B 1 404 ? 18.930 -11.407 -1.000 1.00 17.60 ? 404 ASN B C 1 ATOM 6496 O O . ASN B 1 404 ? 17.970 -11.238 -0.249 1.00 17.43 ? 404 ASN B O 1 ATOM 6497 C CB . ASN B 1 404 ? 19.681 -13.260 0.536 1.00 17.20 ? 404 ASN B CB 1 ATOM 6498 C CG . ASN B 1 404 ? 20.422 -14.576 0.610 1.00 19.19 ? 404 ASN B CG 1 ATOM 6499 O OD1 . ASN B 1 404 ? 20.225 -15.482 -0.213 1.00 19.68 ? 404 ASN B OD1 1 ATOM 6500 N ND2 . ASN B 1 404 ? 21.310 -14.689 1.580 1.00 22.85 ? 404 ASN B ND2 1 ATOM 6501 N N . ASP B 1 405 ? 19.238 -10.602 -2.024 1.00 18.31 ? 405 ASP B N 1 ATOM 6502 C CA . ASP B 1 405 ? 18.397 -9.477 -2.519 1.00 19.99 ? 405 ASP B CA 1 ATOM 6503 C C . ASP B 1 405 ? 18.578 -8.190 -1.760 1.00 21.83 ? 405 ASP B C 1 ATOM 6504 O O . ASP B 1 405 ? 17.874 -7.207 -2.037 1.00 23.23 ? 405 ASP B O 1 ATOM 6505 C CB . ASP B 1 405 ? 16.893 -9.811 -2.584 1.00 18.80 ? 405 ASP B CB 1 ATOM 6506 C CG . ASP B 1 405 ? 16.608 -11.038 -3.414 1.00 20.50 ? 405 ASP B CG 1 ATOM 6507 O OD1 . ASP B 1 405 ? 17.464 -11.457 -4.232 1.00 20.00 ? 405 ASP B OD1 1 ATOM 6508 O OD2 . ASP B 1 405 ? 15.532 -11.642 -3.223 1.00 21.73 ? 405 ASP B OD2 1 ATOM 6509 N N . ARG B 1 406 ? 19.492 -8.203 -0.791 1.00 22.96 ? 406 ARG B N 1 ATOM 6510 C CA . ARG B 1 406 ? 19.927 -6.996 -0.087 1.00 23.62 ? 406 ARG B CA 1 ATOM 6511 C C . ARG B 1 406 ? 21.192 -6.421 -0.717 1.00 23.71 ? 406 ARG B C 1 ATOM 6512 O O . ARG B 1 406 ? 22.225 -7.110 -0.894 1.00 22.42 ? 406 ARG B O 1 ATOM 6513 C CB . ARG B 1 406 ? 20.159 -7.310 1.416 1.00 24.56 ? 406 ARG B CB 1 ATOM 6514 C CG . ARG B 1 406 ? 20.710 -6.182 2.243 1.00 28.20 ? 406 ARG B CG 1 ATOM 6515 C CD . ARG B 1 406 ? 20.940 -6.562 3.728 1.00 32.29 ? 406 ARG B CD 1 ATOM 6516 N NE . ARG B 1 406 ? 21.408 -5.378 4.447 1.00 36.07 ? 406 ARG B NE 1 ATOM 6517 C CZ . ARG B 1 406 ? 22.659 -5.142 4.863 1.00 39.59 ? 406 ARG B CZ 1 ATOM 6518 N NH1 . ARG B 1 406 ? 23.637 -6.050 4.717 1.00 38.18 ? 406 ARG B NH1 1 ATOM 6519 N NH2 . ARG B 1 406 ? 22.925 -3.983 5.482 1.00 40.79 ? 406 ARG B NH2 1 ATOM 6520 N N . VAL B 1 407 ? 21.124 -5.138 -1.065 1.00 23.83 ? 407 VAL B N 1 ATOM 6521 C CA . VAL B 1 407 ? 22.321 -4.492 -1.539 1.00 23.12 ? 407 VAL B CA 1 ATOM 6522 C C . VAL B 1 407 ? 23.255 -4.366 -0.328 1.00 23.72 ? 407 VAL B C 1 ATOM 6523 O O . VAL B 1 407 ? 22.838 -3.880 0.685 1.00 23.58 ? 407 VAL B O 1 ATOM 6524 C CB . VAL B 1 407 ? 22.049 -3.080 -2.111 1.00 22.88 ? 407 VAL B CB 1 ATOM 6525 C CG1 . VAL B 1 407 ? 23.384 -2.448 -2.657 1.00 22.04 ? 407 VAL B CG1 1 ATOM 6526 C CG2 . VAL B 1 407 ? 21.012 -3.116 -3.216 1.00 20.90 ? 407 VAL B CG2 1 ATOM 6527 N N . VAL B 1 408 ? 24.513 -4.791 -0.455 1.00 23.74 ? 408 VAL B N 1 ATOM 6528 C CA . VAL B 1 408 ? 25.487 -4.722 0.617 1.00 22.17 ? 408 VAL B CA 1 ATOM 6529 C C . VAL B 1 408 ? 26.636 -3.868 0.148 1.00 22.43 ? 408 VAL B C 1 ATOM 6530 O O . VAL B 1 408 ? 27.387 -4.289 -0.738 1.00 22.52 ? 408 VAL B O 1 ATOM 6531 C CB . VAL B 1 408 ? 26.081 -6.106 1.003 1.00 22.51 ? 408 VAL B CB 1 ATOM 6532 C CG1 . VAL B 1 408 ? 27.284 -5.920 1.986 1.00 21.23 ? 408 VAL B CG1 1 ATOM 6533 C CG2 . VAL B 1 408 ? 24.996 -7.050 1.567 1.00 20.39 ? 408 VAL B CG2 1 ATOM 6534 N N . PRO B 1 409 ? 26.807 -2.686 0.763 1.00 22.31 ? 409 PRO B N 1 ATOM 6535 C CA . PRO B 1 409 ? 27.791 -1.730 0.331 1.00 22.41 ? 409 PRO B CA 1 ATOM 6536 C C . PRO B 1 409 ? 29.183 -2.330 0.334 1.00 23.22 ? 409 PRO B C 1 ATOM 6537 O O . PRO B 1 409 ? 29.566 -3.006 1.276 1.00 24.27 ? 409 PRO B O 1 ATOM 6538 C CB . PRO B 1 409 ? 27.715 -0.626 1.394 1.00 22.94 ? 409 PRO B CB 1 ATOM 6539 C CG . PRO B 1 409 ? 26.431 -0.770 2.076 1.00 23.59 ? 409 PRO B CG 1 ATOM 6540 C CD . PRO B 1 409 ? 26.034 -2.224 1.934 1.00 22.35 ? 409 PRO B CD 1 ATOM 6541 N N . LEU B 1 410 ? 29.960 -2.094 -0.710 1.00 23.16 ? 410 LEU B N 1 ATOM 6542 C CA . LEU B 1 410 ? 31.294 -2.645 -0.741 1.00 22.40 ? 410 LEU B CA 1 ATOM 6543 C C . LEU B 1 410 ? 32.188 -1.963 0.322 1.00 23.26 ? 410 LEU B C 1 ATOM 6544 O O . LEU B 1 410 ? 31.920 -0.806 0.711 1.00 22.02 ? 410 LEU B O 1 ATOM 6545 C CB . LEU B 1 410 ? 31.839 -2.408 -2.129 1.00 23.04 ? 410 LEU B CB 1 ATOM 6546 C CG . LEU B 1 410 ? 31.011 -2.924 -3.345 1.00 23.96 ? 410 LEU B CG 1 ATOM 6547 C CD1 . LEU B 1 410 ? 31.874 -2.984 -4.593 1.00 20.29 ? 410 LEU B CD1 1 ATOM 6548 C CD2 . LEU B 1 410 ? 30.444 -4.315 -3.024 1.00 21.15 ? 410 LEU B CD2 1 ATOM 6549 N N . HIS B 1 411 ? 33.226 -2.692 0.765 1.00 22.66 ? 411 HIS B N 1 ATOM 6550 C CA . HIS B 1 411 ? 34.317 -2.213 1.629 1.00 22.03 ? 411 HIS B CA 1 ATOM 6551 C C . HIS B 1 411 ? 35.693 -2.312 0.877 1.00 21.87 ? 411 HIS B C 1 ATOM 6552 O O . HIS B 1 411 ? 35.890 -3.146 -0.019 1.00 20.01 ? 411 HIS B O 1 ATOM 6553 C CB . HIS B 1 411 ? 34.351 -3.054 2.920 1.00 22.14 ? 411 HIS B CB 1 ATOM 6554 C CG . HIS B 1 411 ? 33.241 -2.743 3.889 1.00 23.67 ? 411 HIS B CG 1 ATOM 6555 N ND1 . HIS B 1 411 ? 31.994 -3.343 3.818 1.00 26.47 ? 411 HIS B ND1 1 ATOM 6556 C CD2 . HIS B 1 411 ? 33.176 -1.869 4.928 1.00 20.96 ? 411 HIS B CD2 1 ATOM 6557 C CE1 . HIS B 1 411 ? 31.224 -2.864 4.782 1.00 22.66 ? 411 HIS B CE1 1 ATOM 6558 N NE2 . HIS B 1 411 ? 31.914 -1.969 5.461 1.00 21.84 ? 411 HIS B NE2 1 ATOM 6559 N N . GLY B 1 412 ? 36.639 -1.462 1.262 1.00 21.53 ? 412 GLY B N 1 ATOM 6560 C CA . GLY B 1 412 ? 38.009 -1.517 0.738 1.00 21.41 ? 412 GLY B CA 1 ATOM 6561 C C . GLY B 1 412 ? 38.202 -0.505 -0.385 1.00 22.54 ? 412 GLY B C 1 ATOM 6562 O O . GLY B 1 412 ? 39.275 -0.419 -0.982 1.00 20.69 ? 412 GLY B O 1 ATOM 6563 N N . CYS B 1 413 ? 37.147 0.274 -0.664 1.00 22.78 ? 413 CYS B N 1 ATOM 6564 C CA . CYS B 1 413 ? 37.127 1.122 -1.878 1.00 24.32 ? 413 CYS B CA 1 ATOM 6565 C C . CYS B 1 413 ? 36.182 2.288 -1.627 1.00 24.61 ? 413 CYS B C 1 ATOM 6566 O O . CYS B 1 413 ? 35.335 2.190 -0.739 1.00 24.92 ? 413 CYS B O 1 ATOM 6567 C CB . CYS B 1 413 ? 36.705 0.317 -3.140 1.00 23.85 ? 413 CYS B CB 1 ATOM 6568 S SG . CYS B 1 413 ? 35.184 -0.623 -2.993 1.00 23.97 ? 413 CYS B SG 1 ATOM 6569 N N . PRO B 1 414 ? 36.298 3.377 -2.400 1.00 24.90 ? 414 PRO B N 1 ATOM 6570 C CA . PRO B 1 414 ? 35.364 4.497 -2.093 1.00 25.73 ? 414 PRO B CA 1 ATOM 6571 C C . PRO B 1 414 ? 33.962 4.215 -2.584 1.00 26.48 ? 414 PRO B C 1 ATOM 6572 O O . PRO B 1 414 ? 33.670 4.506 -3.751 1.00 27.34 ? 414 PRO B O 1 ATOM 6573 C CB . PRO B 1 414 ? 35.951 5.708 -2.876 1.00 25.63 ? 414 PRO B CB 1 ATOM 6574 C CG . PRO B 1 414 ? 37.310 5.160 -3.514 1.00 25.89 ? 414 PRO B CG 1 ATOM 6575 C CD . PRO B 1 414 ? 37.212 3.668 -3.524 1.00 24.00 ? 414 PRO B CD 1 ATOM 6576 N N . VAL B 1 415 ? 33.102 3.671 -1.711 1.00 27.54 ? 415 VAL B N 1 ATOM 6577 C CA . VAL B 1 415 ? 31.711 3.405 -2.058 1.00 28.31 ? 415 VAL B CA 1 ATOM 6578 C C . VAL B 1 415 ? 30.859 4.605 -2.185 1.00 28.68 ? 415 VAL B C 1 ATOM 6579 O O . VAL B 1 415 ? 30.906 5.480 -1.318 1.00 30.01 ? 415 VAL B O 1 ATOM 6580 C CB . VAL B 1 415 ? 30.911 2.599 -0.987 1.00 29.95 ? 415 VAL B CB 1 ATOM 6581 C CG1 . VAL B 1 415 ? 30.625 1.204 -1.448 1.00 29.87 ? 415 VAL B CG1 1 ATOM 6582 C CG2 . VAL B 1 415 ? 31.506 2.686 0.431 1.00 29.10 ? 415 VAL B CG2 1 ATOM 6583 N N . ASP B 1 416 ? 29.992 4.594 -3.199 1.00 29.10 ? 416 ASP B N 1 ATOM 6584 C CA . ASP B 1 416 ? 29.019 5.642 -3.420 1.00 28.66 ? 416 ASP B CA 1 ATOM 6585 C C . ASP B 1 416 ? 27.746 5.324 -2.649 1.00 28.93 ? 416 ASP B C 1 ATOM 6586 O O . ASP B 1 416 ? 27.675 4.306 -1.986 1.00 29.31 ? 416 ASP B O 1 ATOM 6587 C CB . ASP B 1 416 ? 28.784 5.868 -4.931 1.00 29.35 ? 416 ASP B CB 1 ATOM 6588 C CG . ASP B 1 416 ? 28.110 4.657 -5.644 1.00 29.95 ? 416 ASP B CG 1 ATOM 6589 O OD1 . ASP B 1 416 ? 27.257 3.955 -5.046 1.00 26.85 ? 416 ASP B OD1 1 ATOM 6590 O OD2 . ASP B 1 416 ? 28.438 4.445 -6.828 1.00 30.57 ? 416 ASP B OD2 1 ATOM 6591 N N . ALA B 1 417 ? 26.755 6.196 -2.684 1.00 29.16 ? 417 ALA B N 1 ATOM 6592 C CA . ALA B 1 417 ? 25.593 6.028 -1.817 1.00 29.61 ? 417 ALA B CA 1 ATOM 6593 C C . ALA B 1 417 ? 24.668 4.960 -2.365 1.00 30.09 ? 417 ALA B C 1 ATOM 6594 O O . ALA B 1 417 ? 23.597 4.662 -1.764 1.00 30.49 ? 417 ALA B O 1 ATOM 6595 C CB . ALA B 1 417 ? 24.820 7.361 -1.657 1.00 30.29 ? 417 ALA B CB 1 ATOM 6596 N N . LEU B 1 418 ? 25.034 4.388 -3.512 1.00 29.09 ? 418 LEU B N 1 ATOM 6597 C CA . LEU B 1 418 ? 24.230 3.266 -4.018 1.00 28.61 ? 418 LEU B CA 1 ATOM 6598 C C . LEU B 1 418 ? 24.904 1.899 -3.762 1.00 27.36 ? 418 LEU B C 1 ATOM 6599 O O . LEU B 1 418 ? 24.442 0.882 -4.260 1.00 26.93 ? 418 LEU B O 1 ATOM 6600 C CB . LEU B 1 418 ? 23.829 3.478 -5.485 1.00 29.15 ? 418 LEU B CB 1 ATOM 6601 C CG . LEU B 1 418 ? 22.882 4.674 -5.777 1.00 31.44 ? 418 LEU B CG 1 ATOM 6602 C CD1 . LEU B 1 418 ? 22.698 4.942 -7.295 1.00 30.19 ? 418 LEU B CD1 1 ATOM 6603 C CD2 . LEU B 1 418 ? 21.508 4.568 -5.051 1.00 31.60 ? 418 LEU B CD2 1 ATOM 6604 N N . GLY B 1 419 ? 26.005 1.902 -3.003 1.00 25.08 ? 419 GLY B N 1 ATOM 6605 C CA . GLY B 1 419 ? 26.631 0.673 -2.610 1.00 22.85 ? 419 GLY B CA 1 ATOM 6606 C C . GLY B 1 419 ? 27.793 0.264 -3.471 1.00 22.24 ? 419 GLY B C 1 ATOM 6607 O O . GLY B 1 419 ? 28.369 -0.732 -3.193 1.00 20.65 ? 419 GLY B O 1 ATOM 6608 N N . ARG B 1 420 ? 28.186 1.077 -4.456 1.00 21.99 ? 420 ARG B N 1 ATOM 6609 C CA . ARG B 1 420 ? 29.068 0.612 -5.537 1.00 22.89 ? 420 ARG B CA 1 ATOM 6610 C C . ARG B 1 420 ? 30.441 1.240 -5.511 1.00 22.99 ? 420 ARG B C 1 ATOM 6611 O O . ARG B 1 420 ? 30.644 2.325 -4.969 1.00 23.51 ? 420 ARG B O 1 ATOM 6612 C CB . ARG B 1 420 ? 28.436 0.937 -6.909 1.00 23.24 ? 420 ARG B CB 1 ATOM 6613 C CG . ARG B 1 420 ? 26.888 0.764 -6.988 1.00 24.30 ? 420 ARG B CG 1 ATOM 6614 C CD . ARG B 1 420 ? 26.346 1.348 -8.294 1.00 26.69 ? 420 ARG B CD 1 ATOM 6615 N NE . ARG B 1 420 ? 26.452 2.803 -8.304 1.00 26.00 ? 420 ARG B NE 1 ATOM 6616 C CZ . ARG B 1 420 ? 25.808 3.607 -9.158 1.00 29.63 ? 420 ARG B CZ 1 ATOM 6617 N NH1 . ARG B 1 420 ? 25.010 3.097 -10.091 1.00 32.53 ? 420 ARG B NH1 1 ATOM 6618 N NH2 . ARG B 1 420 ? 25.958 4.927 -9.092 1.00 25.83 ? 420 ARG B NH2 1 ATOM 6619 N N . CYS B 1 421 ? 31.394 0.597 -6.144 1.00 23.66 ? 421 CYS B N 1 ATOM 6620 C CA . CYS B 1 421 ? 32.702 1.224 -6.329 1.00 25.46 ? 421 CYS B CA 1 ATOM 6621 C C . CYS B 1 421 ? 33.079 0.939 -7.737 1.00 25.67 ? 421 CYS B C 1 ATOM 6622 O O . CYS B 1 421 ? 32.643 -0.070 -8.288 1.00 25.45 ? 421 CYS B O 1 ATOM 6623 C CB . CYS B 1 421 ? 33.796 0.555 -5.463 1.00 25.67 ? 421 CYS B CB 1 ATOM 6624 S SG . CYS B 1 421 ? 33.678 0.626 -3.630 1.00 31.78 ? 421 CYS B SG 1 ATOM 6625 N N . THR B 1 422 ? 33.953 1.757 -8.312 1.00 25.47 ? 422 THR B N 1 ATOM 6626 C CA . THR B 1 422 ? 34.476 1.410 -9.609 1.00 25.64 ? 422 THR B CA 1 ATOM 6627 C C . THR B 1 422 ? 35.211 0.074 -9.533 1.00 26.11 ? 422 THR B C 1 ATOM 6628 O O . THR B 1 422 ? 35.852 -0.216 -8.533 1.00 27.39 ? 422 THR B O 1 ATOM 6629 C CB . THR B 1 422 ? 35.434 2.473 -10.152 1.00 25.95 ? 422 THR B CB 1 ATOM 6630 O OG1 . THR B 1 422 ? 36.683 2.364 -9.459 1.00 26.18 ? 422 THR B OG1 1 ATOM 6631 C CG2 . THR B 1 422 ? 34.830 3.899 -10.018 1.00 23.58 ? 422 THR B CG2 1 ATOM 6632 N N . ARG B 1 423 ? 35.141 -0.704 -10.606 1.00 25.43 ? 423 ARG B N 1 ATOM 6633 C CA . ARG B 1 423 ? 35.838 -1.953 -10.750 1.00 26.15 ? 423 ARG B CA 1 ATOM 6634 C C . ARG B 1 423 ? 37.295 -1.886 -10.332 1.00 26.42 ? 423 ARG B C 1 ATOM 6635 O O . ARG B 1 423 ? 37.774 -2.729 -9.546 1.00 26.82 ? 423 ARG B O 1 ATOM 6636 C CB . ARG B 1 423 ? 35.747 -2.400 -12.219 1.00 26.14 ? 423 ARG B CB 1 ATOM 6637 C CG . ARG B 1 423 ? 36.006 -3.840 -12.492 1.00 26.42 ? 423 ARG B CG 1 ATOM 6638 C CD . ARG B 1 423 ? 37.309 -4.076 -13.262 1.00 32.53 ? 423 ARG B CD 1 ATOM 6639 N NE . ARG B 1 423 ? 37.546 -3.168 -14.390 1.00 30.60 ? 423 ARG B NE 1 ATOM 6640 C CZ . ARG B 1 423 ? 37.209 -3.417 -15.655 1.00 32.31 ? 423 ARG B CZ 1 ATOM 6641 N NH1 . ARG B 1 423 ? 36.610 -4.552 -15.997 1.00 32.05 ? 423 ARG B NH1 1 ATOM 6642 N NH2 . ARG B 1 423 ? 37.471 -2.516 -16.594 1.00 30.50 ? 423 ARG B NH2 1 ATOM 6643 N N . ASP B 1 424 ? 38.005 -0.894 -10.839 1.00 26.75 ? 424 ASP B N 1 ATOM 6644 C CA . ASP B 1 424 ? 39.453 -0.772 -10.570 1.00 27.95 ? 424 ASP B CA 1 ATOM 6645 C C . ASP B 1 424 ? 39.727 -0.564 -9.078 1.00 26.64 ? 424 ASP B C 1 ATOM 6646 O O . ASP B 1 424 ? 40.609 -1.219 -8.507 1.00 25.35 ? 424 ASP B O 1 ATOM 6647 C CB . ASP B 1 424 ? 40.101 0.343 -11.416 1.00 29.24 ? 424 ASP B CB 1 ATOM 6648 C CG . ASP B 1 424 ? 40.302 -0.068 -12.915 1.00 35.15 ? 424 ASP B CG 1 ATOM 6649 O OD1 . ASP B 1 424 ? 39.973 -1.242 -13.311 1.00 38.48 ? 424 ASP B OD1 1 ATOM 6650 O OD2 . ASP B 1 424 ? 40.817 0.807 -13.688 1.00 41.63 ? 424 ASP B OD2 1 ATOM 6651 N N . SER B 1 425 ? 38.910 0.288 -8.445 1.00 26.24 ? 425 SER B N 1 ATOM 6652 C CA . SER B 1 425 ? 39.073 0.558 -7.015 1.00 25.58 ? 425 SER B CA 1 ATOM 6653 C C . SER B 1 425 ? 38.610 -0.645 -6.156 1.00 25.48 ? 425 SER B C 1 ATOM 6654 O O . SER B 1 425 ? 39.237 -0.937 -5.149 1.00 25.84 ? 425 SER B O 1 ATOM 6655 C CB . SER B 1 425 ? 38.372 1.818 -6.590 1.00 24.57 ? 425 SER B CB 1 ATOM 6656 O OG . SER B 1 425 ? 36.980 1.587 -6.477 1.00 24.53 ? 425 SER B OG 1 ATOM 6657 N N . PHE B 1 426 ? 37.556 -1.341 -6.572 1.00 24.39 ? 426 PHE B N 1 ATOM 6658 C CA . PHE B 1 426 ? 37.147 -2.571 -5.931 1.00 23.85 ? 426 PHE B CA 1 ATOM 6659 C C . PHE B 1 426 ? 38.226 -3.639 -5.960 1.00 24.15 ? 426 PHE B C 1 ATOM 6660 O O . PHE B 1 426 ? 38.494 -4.255 -4.955 1.00 24.76 ? 426 PHE B O 1 ATOM 6661 C CB . PHE B 1 426 ? 35.894 -3.116 -6.589 1.00 23.85 ? 426 PHE B CB 1 ATOM 6662 C CG . PHE B 1 426 ? 35.418 -4.419 -6.013 1.00 22.02 ? 426 PHE B CG 1 ATOM 6663 C CD1 . PHE B 1 426 ? 34.896 -4.477 -4.718 1.00 23.06 ? 426 PHE B CD1 1 ATOM 6664 C CD2 . PHE B 1 426 ? 35.486 -5.597 -6.755 1.00 20.97 ? 426 PHE B CD2 1 ATOM 6665 C CE1 . PHE B 1 426 ? 34.425 -5.696 -4.168 1.00 20.44 ? 426 PHE B CE1 1 ATOM 6666 C CE2 . PHE B 1 426 ? 35.040 -6.836 -6.202 1.00 18.50 ? 426 PHE B CE2 1 ATOM 6667 C CZ . PHE B 1 426 ? 34.497 -6.874 -4.935 1.00 17.54 ? 426 PHE B CZ 1 ATOM 6668 N N . VAL B 1 427 ? 38.835 -3.871 -7.109 1.00 24.50 ? 427 VAL B N 1 ATOM 6669 C CA . VAL B 1 427 ? 39.867 -4.893 -7.231 1.00 24.81 ? 427 VAL B CA 1 ATOM 6670 C C . VAL B 1 427 ? 41.105 -4.532 -6.409 1.00 25.83 ? 427 VAL B C 1 ATOM 6671 O O . VAL B 1 427 ? 41.651 -5.368 -5.662 1.00 26.30 ? 427 VAL B O 1 ATOM 6672 C CB . VAL B 1 427 ? 40.211 -5.203 -8.709 1.00 24.90 ? 427 VAL B CB 1 ATOM 6673 C CG1 . VAL B 1 427 ? 41.539 -5.993 -8.852 1.00 23.54 ? 427 VAL B CG1 1 ATOM 6674 C CG2 . VAL B 1 427 ? 39.042 -5.956 -9.372 1.00 21.56 ? 427 VAL B CG2 1 ATOM 6675 N N . ARG B 1 428 ? 41.543 -3.300 -6.527 1.00 25.71 ? 428 ARG B N 1 ATOM 6676 C CA . ARG B 1 428 ? 42.592 -2.815 -5.650 1.00 26.65 ? 428 ARG B CA 1 ATOM 6677 C C . ARG B 1 428 ? 42.250 -2.987 -4.149 1.00 24.98 ? 428 ARG B C 1 ATOM 6678 O O . ARG B 1 428 ? 43.055 -3.490 -3.417 1.00 25.33 ? 428 ARG B O 1 ATOM 6679 C CB . ARG B 1 428 ? 42.948 -1.395 -6.031 1.00 27.71 ? 428 ARG B CB 1 ATOM 6680 C CG . ARG B 1 428 ? 43.945 -0.705 -5.104 1.00 34.22 ? 428 ARG B CG 1 ATOM 6681 C CD . ARG B 1 428 ? 43.333 0.640 -4.816 1.00 40.73 ? 428 ARG B CD 1 ATOM 6682 N NE . ARG B 1 428 ? 44.285 1.737 -4.684 1.00 51.42 ? 428 ARG B NE 1 ATOM 6683 C CZ . ARG B 1 428 ? 43.980 3.007 -4.983 1.00 55.51 ? 428 ARG B CZ 1 ATOM 6684 N NH1 . ARG B 1 428 ? 42.763 3.291 -5.475 1.00 56.74 ? 428 ARG B NH1 1 ATOM 6685 N NH2 . ARG B 1 428 ? 44.878 3.981 -4.808 1.00 54.79 ? 428 ARG B NH2 1 ATOM 6686 N N . GLY B 1 429 ? 41.036 -2.672 -3.698 1.00 24.50 ? 429 GLY B N 1 ATOM 6687 C CA . GLY B 1 429 ? 40.652 -3.003 -2.296 1.00 23.21 ? 429 GLY B CA 1 ATOM 6688 C C . GLY B 1 429 ? 40.843 -4.465 -1.835 1.00 22.47 ? 429 GLY B C 1 ATOM 6689 O O . GLY B 1 429 ? 41.029 -4.742 -0.651 1.00 23.58 ? 429 GLY B O 1 ATOM 6690 N N . LEU B 1 430 ? 40.797 -5.408 -2.777 1.00 20.38 ? 430 LEU B N 1 ATOM 6691 C CA . LEU B 1 430 ? 40.866 -6.827 -2.477 1.00 18.53 ? 430 LEU B CA 1 ATOM 6692 C C . LEU B 1 430 ? 42.300 -7.306 -2.387 1.00 17.59 ? 430 LEU B C 1 ATOM 6693 O O . LEU B 1 430 ? 42.612 -8.421 -2.801 1.00 17.84 ? 430 LEU B O 1 ATOM 6694 C CB . LEU B 1 430 ? 40.084 -7.641 -3.524 1.00 18.56 ? 430 LEU B CB 1 ATOM 6695 C CG . LEU B 1 430 ? 38.555 -7.475 -3.588 1.00 17.31 ? 430 LEU B CG 1 ATOM 6696 C CD1 . LEU B 1 430 ? 38.040 -8.442 -4.665 1.00 16.71 ? 430 LEU B CD1 1 ATOM 6697 C CD2 . LEU B 1 430 ? 37.847 -7.778 -2.255 1.00 13.30 ? 430 LEU B CD2 1 ATOM 6698 N N . SER B 1 431 ? 43.156 -6.449 -1.843 1.00 16.45 ? 431 SER B N 1 ATOM 6699 C CA . SER B 1 431 ? 44.587 -6.757 -1.605 1.00 16.97 ? 431 SER B CA 1 ATOM 6700 C C . SER B 1 431 ? 44.782 -7.965 -0.712 1.00 16.40 ? 431 SER B C 1 ATOM 6701 O O . SER B 1 431 ? 45.788 -8.614 -0.856 1.00 16.73 ? 431 SER B O 1 ATOM 6702 C CB . SER B 1 431 ? 45.322 -5.549 -0.964 1.00 16.96 ? 431 SER B CB 1 ATOM 6703 O OG . SER B 1 431 ? 44.531 -5.006 0.108 1.00 16.85 ? 431 SER B OG 1 ATOM 6704 N N . PHE B 1 432 ? 43.829 -8.276 0.183 1.00 16.29 ? 432 PHE B N 1 ATOM 6705 C CA . PHE B 1 432 ? 43.947 -9.464 1.034 1.00 17.36 ? 432 PHE B CA 1 ATOM 6706 C C . PHE B 1 432 ? 43.908 -10.678 0.118 1.00 18.22 ? 432 PHE B C 1 ATOM 6707 O O . PHE B 1 432 ? 44.841 -11.467 0.093 1.00 18.01 ? 432 PHE B O 1 ATOM 6708 C CB . PHE B 1 432 ? 42.863 -9.481 2.140 1.00 18.89 ? 432 PHE B CB 1 ATOM 6709 C CG . PHE B 1 432 ? 42.763 -10.800 2.924 1.00 18.30 ? 432 PHE B CG 1 ATOM 6710 C CD1 . PHE B 1 432 ? 43.550 -11.035 4.053 1.00 19.83 ? 432 PHE B CD1 1 ATOM 6711 C CD2 . PHE B 1 432 ? 41.876 -11.778 2.524 1.00 18.21 ? 432 PHE B CD2 1 ATOM 6712 C CE1 . PHE B 1 432 ? 43.475 -12.204 4.759 1.00 16.43 ? 432 PHE B CE1 1 ATOM 6713 C CE2 . PHE B 1 432 ? 41.768 -12.956 3.203 1.00 19.76 ? 432 PHE B CE2 1 ATOM 6714 C CZ . PHE B 1 432 ? 42.579 -13.209 4.326 1.00 21.26 ? 432 PHE B CZ 1 ATOM 6715 N N . ALA B 1 433 ? 42.844 -10.830 -0.672 1.00 18.48 ? 433 ALA B N 1 ATOM 6716 C CA . ALA B 1 433 ? 42.793 -11.970 -1.610 1.00 18.54 ? 433 ALA B CA 1 ATOM 6717 C C . ALA B 1 433 ? 43.960 -11.877 -2.629 1.00 19.68 ? 433 ALA B C 1 ATOM 6718 O O . ALA B 1 433 ? 44.622 -12.884 -2.925 1.00 18.87 ? 433 ALA B O 1 ATOM 6719 C CB . ALA B 1 433 ? 41.436 -12.025 -2.287 1.00 17.01 ? 433 ALA B CB 1 ATOM 6720 N N . ARG B 1 434 ? 44.261 -10.678 -3.148 1.00 21.50 ? 434 ARG B N 1 ATOM 6721 C CA . ARG B 1 434 ? 45.310 -10.630 -4.209 1.00 23.28 ? 434 ARG B CA 1 ATOM 6722 C C . ARG B 1 434 ? 46.667 -11.179 -3.715 1.00 23.91 ? 434 ARG B C 1 ATOM 6723 O O . ARG B 1 434 ? 47.428 -11.835 -4.502 1.00 24.37 ? 434 ARG B O 1 ATOM 6724 C CB . ARG B 1 434 ? 45.460 -9.228 -4.863 1.00 23.18 ? 434 ARG B CB 1 ATOM 6725 C CG . ARG B 1 434 ? 44.200 -8.735 -5.590 1.00 24.19 ? 434 ARG B CG 1 ATOM 6726 C CD . ARG B 1 434 ? 44.396 -7.459 -6.421 1.00 23.18 ? 434 ARG B CD 1 ATOM 6727 N NE . ARG B 1 434 ? 44.439 -6.245 -5.578 1.00 25.63 ? 434 ARG B NE 1 ATOM 6728 C CZ . ARG B 1 434 ? 45.567 -5.637 -5.193 1.00 25.82 ? 434 ARG B CZ 1 ATOM 6729 N NH1 . ARG B 1 434 ? 46.735 -6.123 -5.587 1.00 22.58 ? 434 ARG B NH1 1 ATOM 6730 N NH2 . ARG B 1 434 ? 45.536 -4.534 -4.431 1.00 23.05 ? 434 ARG B NH2 1 ATOM 6731 N N . SER B 1 435 ? 46.964 -10.954 -2.429 1.00 23.71 ? 435 SER B N 1 ATOM 6732 C CA . SER B 1 435 ? 48.281 -11.344 -1.852 1.00 24.21 ? 435 SER B CA 1 ATOM 6733 C C . SER B 1 435 ? 48.281 -12.782 -1.395 1.00 23.62 ? 435 SER B C 1 ATOM 6734 O O . SER B 1 435 ? 49.299 -13.300 -0.890 1.00 24.30 ? 435 SER B O 1 ATOM 6735 C CB . SER B 1 435 ? 48.704 -10.408 -0.693 1.00 24.54 ? 435 SER B CB 1 ATOM 6736 O OG . SER B 1 435 ? 47.674 -10.300 0.295 1.00 26.10 ? 435 SER B OG 1 ATOM 6737 N N . GLY B 1 436 ? 47.149 -13.449 -1.576 1.00 22.86 ? 436 GLY B N 1 ATOM 6738 C CA . GLY B 1 436 ? 47.024 -14.849 -1.119 1.00 22.39 ? 436 GLY B CA 1 ATOM 6739 C C . GLY B 1 436 ? 46.469 -15.025 0.296 1.00 22.50 ? 436 GLY B C 1 ATOM 6740 O O . GLY B 1 436 ? 46.558 -16.119 0.846 1.00 22.17 ? 436 GLY B O 1 ATOM 6741 N N . GLY B 1 437 ? 45.915 -13.950 0.888 1.00 22.33 ? 437 GLY B N 1 ATOM 6742 C CA . GLY B 1 437 ? 45.549 -13.897 2.320 1.00 22.54 ? 437 GLY B CA 1 ATOM 6743 C C . GLY B 1 437 ? 46.562 -14.648 3.164 1.00 22.97 ? 437 GLY B C 1 ATOM 6744 O O . GLY B 1 437 ? 47.759 -14.488 2.938 1.00 23.00 ? 437 GLY B O 1 ATOM 6745 N N . ASP B 1 438 ? 46.099 -15.535 4.057 1.00 22.44 ? 438 ASP B N 1 ATOM 6746 C CA . ASP B 1 438 ? 47.011 -16.173 5.035 1.00 23.05 ? 438 ASP B CA 1 ATOM 6747 C C . ASP B 1 438 ? 47.193 -17.600 4.674 1.00 23.51 ? 438 ASP B C 1 ATOM 6748 O O . ASP B 1 438 ? 47.375 -18.452 5.556 1.00 23.73 ? 438 ASP B O 1 ATOM 6749 C CB . ASP B 1 438 ? 46.478 -16.030 6.494 1.00 22.16 ? 438 ASP B CB 1 ATOM 6750 C CG . ASP B 1 438 ? 46.235 -14.576 6.861 1.00 22.46 ? 438 ASP B CG 1 ATOM 6751 O OD1 . ASP B 1 438 ? 47.132 -13.766 6.622 1.00 22.57 ? 438 ASP B OD1 1 ATOM 6752 O OD2 . ASP B 1 438 ? 45.112 -14.200 7.260 1.00 23.33 ? 438 ASP B OD2 1 ATOM 6753 N N . TRP B 1 439 ? 47.106 -17.874 3.374 1.00 23.66 ? 439 TRP B N 1 ATOM 6754 C CA . TRP B 1 439 ? 47.216 -19.252 2.887 1.00 23.76 ? 439 TRP B CA 1 ATOM 6755 C C . TRP B 1 439 ? 48.563 -19.922 3.273 1.00 25.64 ? 439 TRP B C 1 ATOM 6756 O O . TRP B 1 439 ? 48.617 -21.143 3.443 1.00 25.47 ? 439 TRP B O 1 ATOM 6757 C CB . TRP B 1 439 ? 46.988 -19.325 1.357 1.00 22.92 ? 439 TRP B CB 1 ATOM 6758 C CG . TRP B 1 439 ? 46.849 -20.747 0.847 1.00 19.14 ? 439 TRP B CG 1 ATOM 6759 C CD1 . TRP B 1 439 ? 47.833 -21.522 0.348 1.00 19.92 ? 439 TRP B CD1 1 ATOM 6760 C CD2 . TRP B 1 439 ? 45.663 -21.554 0.848 1.00 19.40 ? 439 TRP B CD2 1 ATOM 6761 N NE1 . TRP B 1 439 ? 47.348 -22.770 0.026 1.00 20.34 ? 439 TRP B NE1 1 ATOM 6762 C CE2 . TRP B 1 439 ? 46.014 -22.811 0.328 1.00 19.82 ? 439 TRP B CE2 1 ATOM 6763 C CE3 . TRP B 1 439 ? 44.334 -21.329 1.230 1.00 20.82 ? 439 TRP B CE3 1 ATOM 6764 C CZ2 . TRP B 1 439 ? 45.097 -23.847 0.201 1.00 18.83 ? 439 TRP B CZ2 1 ATOM 6765 C CZ3 . TRP B 1 439 ? 43.401 -22.351 1.069 1.00 20.14 ? 439 TRP B CZ3 1 ATOM 6766 C CH2 . TRP B 1 439 ? 43.796 -23.595 0.546 1.00 19.32 ? 439 TRP B CH2 1 ATOM 6767 N N . ALA B 1 440 ? 49.640 -19.135 3.362 1.00 27.15 ? 440 ALA B N 1 ATOM 6768 C CA . ALA B 1 440 ? 50.964 -19.670 3.745 1.00 29.39 ? 440 ALA B CA 1 ATOM 6769 C C . ALA B 1 440 ? 50.915 -20.354 5.132 1.00 30.80 ? 440 ALA B C 1 ATOM 6770 O O . ALA B 1 440 ? 51.669 -21.289 5.381 1.00 31.00 ? 440 ALA B O 1 ATOM 6771 C CB . ALA B 1 440 ? 52.059 -18.564 3.680 1.00 28.34 ? 440 ALA B CB 1 ATOM 6772 N N . GLU B 1 441 ? 49.969 -19.931 5.981 1.00 31.84 ? 441 GLU B N 1 ATOM 6773 C CA . GLU B 1 441 ? 49.799 -20.461 7.339 1.00 33.89 ? 441 GLU B CA 1 ATOM 6774 C C . GLU B 1 441 ? 48.973 -21.725 7.392 1.00 33.96 ? 441 GLU B C 1 ATOM 6775 O O . GLU B 1 441 ? 48.755 -22.268 8.466 1.00 33.61 ? 441 GLU B O 1 ATOM 6776 C CB . GLU B 1 441 ? 49.194 -19.393 8.263 1.00 34.36 ? 441 GLU B CB 1 ATOM 6777 C CG . GLU B 1 441 ? 50.136 -18.169 8.416 1.00 39.28 ? 441 GLU B CG 1 ATOM 6778 C CD . GLU B 1 441 ? 49.530 -16.979 9.170 1.00 46.32 ? 441 GLU B CD 1 ATOM 6779 O OE1 . GLU B 1 441 ? 48.435 -17.126 9.776 1.00 47.07 ? 441 GLU B OE1 1 ATOM 6780 O OE2 . GLU B 1 441 ? 50.174 -15.891 9.154 1.00 48.62 ? 441 GLU B OE2 1 ATOM 6781 N N . CYS B 1 442 ? 48.506 -22.199 6.239 1.00 34.13 ? 442 CYS B N 1 ATOM 6782 C CA . CYS B 1 442 ? 47.837 -23.501 6.164 1.00 34.66 ? 442 CYS B CA 1 ATOM 6783 C C . CYS B 1 442 ? 48.761 -24.672 6.532 1.00 36.80 ? 442 CYS B C 1 ATOM 6784 O O . CYS B 1 442 ? 48.289 -25.785 6.811 1.00 36.57 ? 442 CYS B O 1 ATOM 6785 C CB . CYS B 1 442 ? 47.222 -23.745 4.770 1.00 33.85 ? 442 CYS B CB 1 ATOM 6786 S SG . CYS B 1 442 ? 45.800 -22.682 4.332 1.00 28.03 ? 442 CYS B SG 1 ATOM 6787 N N . PHE B 1 443 ? 50.065 -24.426 6.548 1.00 39.55 ? 443 PHE B N 1 ATOM 6788 C CA . PHE B 1 443 ? 51.023 -25.520 6.626 1.00 42.74 ? 443 PHE B CA 1 ATOM 6789 C C . PHE B 1 443 ? 52.021 -25.416 7.774 1.00 45.22 ? 443 PHE B C 1 ATOM 6790 O O . PHE B 1 443 ? 52.588 -24.398 7.994 1.00 45.86 ? 443 PHE B O 1 ATOM 6791 C CB . PHE B 1 443 ? 51.690 -25.667 5.259 1.00 42.47 ? 443 PHE B CB 1 ATOM 6792 C CG . PHE B 1 443 ? 50.682 -25.831 4.162 1.00 42.41 ? 443 PHE B CG 1 ATOM 6793 C CD1 . PHE B 1 443 ? 49.856 -26.961 4.135 1.00 42.38 ? 443 PHE B CD1 1 ATOM 6794 C CD2 . PHE B 1 443 ? 50.479 -24.826 3.225 1.00 44.23 ? 443 PHE B CD2 1 ATOM 6795 C CE1 . PHE B 1 443 ? 48.884 -27.118 3.179 1.00 42.01 ? 443 PHE B CE1 1 ATOM 6796 C CE2 . PHE B 1 443 ? 49.499 -24.975 2.229 1.00 45.17 ? 443 PHE B CE2 1 ATOM 6797 C CZ . PHE B 1 443 ? 48.697 -26.126 2.221 1.00 44.71 ? 443 PHE B CZ 1 ATOM 6798 N N . ALA B 1 444 ? 52.249 -26.476 8.529 1.00 47.82 ? 444 ALA B N 1 ATOM 6799 C CA . ALA B 1 444 ? 53.278 -26.342 9.576 1.00 50.01 ? 444 ALA B CA 1 ATOM 6800 C C . ALA B 1 444 ? 54.700 -26.450 8.967 1.00 51.15 ? 444 ALA B C 1 ATOM 6801 O O . ALA B 1 444 ? 55.148 -25.573 8.186 1.00 51.42 ? 444 ALA B O 1 ATOM 6802 C CB . ALA B 1 444 ? 53.046 -27.351 10.759 1.00 50.52 ? 444 ALA B CB 1 ATOM 6803 O OXT . ALA B 1 444 ? 55.440 -27.425 9.222 1.00 52.33 ? 444 ALA B OXT 1 HETATM 6804 C C1 . IHS C 2 . ? -5.427 11.567 35.395 0.77 25.99 ? 500 IHS A C1 1 HETATM 6805 O O1 . IHS C 2 . ? -6.286 12.439 35.996 0.77 30.15 ? 500 IHS A O1 1 HETATM 6806 S S1 . IHS C 2 . ? -6.346 13.846 35.436 0.77 30.42 ? 500 IHS A S1 1 HETATM 6807 C C2 . IHS C 2 . ? -6.225 10.500 34.673 0.77 23.76 ? 500 IHS A C2 1 HETATM 6808 O O2 . IHS C 2 . ? -5.351 14.669 36.136 0.77 32.70 ? 500 IHS A O2 1 HETATM 6809 S S2 . IHS C 2 . ? -8.619 10.311 35.688 0.77 27.54 ? 500 IHS A S2 1 HETATM 6810 C C3 . IHS C 2 . ? -5.241 9.527 34.060 0.77 21.32 ? 500 IHS A C3 1 HETATM 6811 O O3 . IHS C 2 . ? -7.732 14.104 35.865 0.77 28.11 ? 500 IHS A O3 1 HETATM 6812 S S3 . IHS C 2 . ? -6.323 8.392 32.187 0.77 15.43 ? 500 IHS A S3 1 HETATM 6813 C C4 . IHS C 2 . ? -3.913 9.327 34.757 0.77 23.40 ? 500 IHS A C4 1 HETATM 6814 O O4 . IHS C 2 . ? -6.292 14.040 33.977 0.77 29.61 ? 500 IHS A O4 1 HETATM 6815 S S4 . IHS C 2 . ? -2.391 7.671 33.689 0.77 25.43 ? 500 IHS A S4 1 HETATM 6816 C C5 . IHS C 2 . ? -3.343 10.637 35.329 0.77 26.82 ? 500 IHS A C5 1 HETATM 6817 S S5 . IHS C 2 . ? -0.848 11.249 35.276 0.77 30.69 ? 500 IHS A S5 1 HETATM 6818 C C6 . IHS C 2 . ? -4.347 11.126 36.357 0.77 27.28 ? 500 IHS A C6 1 HETATM 6819 S S6 . IHS C 2 . ? -3.577 12.448 38.514 0.77 30.99 ? 500 IHS A S6 1 HETATM 6820 O O12 . IHS C 2 . ? -7.215 9.794 35.399 0.77 27.65 ? 500 IHS A O12 1 HETATM 6821 O O13 . IHS C 2 . ? -5.890 8.312 33.651 0.77 19.95 ? 500 IHS A O13 1 HETATM 6822 O O14 . IHS C 2 . ? -3.140 8.975 33.645 0.77 24.68 ? 500 IHS A O14 1 HETATM 6823 O O15 . IHS C 2 . ? -2.042 10.511 35.882 0.77 29.79 ? 500 IHS A O15 1 HETATM 6824 O O16 . IHS C 2 . ? -3.801 12.271 37.000 0.77 31.24 ? 500 IHS A O16 1 HETATM 6825 O O22 . IHS C 2 . ? -8.555 11.022 36.994 0.77 32.44 ? 500 IHS A O22 1 HETATM 6826 O O23 . IHS C 2 . ? -6.845 7.060 31.827 0.77 16.98 ? 500 IHS A O23 1 HETATM 6827 O O24 . IHS C 2 . ? -2.177 7.067 32.371 0.77 26.53 ? 500 IHS A O24 1 HETATM 6828 O O25 . IHS C 2 . ? -0.847 11.076 33.822 0.77 29.55 ? 500 IHS A O25 1 HETATM 6829 O O26 . IHS C 2 . ? -2.666 11.362 38.941 0.77 30.66 ? 500 IHS A O26 1 HETATM 6830 O O32 . IHS C 2 . ? -9.109 11.283 34.716 0.77 29.54 ? 500 IHS A O32 1 HETATM 6831 O O33 . IHS C 2 . ? -5.122 8.834 31.409 0.77 11.28 ? 500 IHS A O33 1 HETATM 6832 O O34 . IHS C 2 . ? -3.037 6.715 34.583 0.77 21.60 ? 500 IHS A O34 1 HETATM 6833 O O35 . IHS C 2 . ? -0.935 12.677 35.606 0.77 32.77 ? 500 IHS A O35 1 HETATM 6834 O O36 . IHS C 2 . ? -4.852 12.410 39.247 0.77 27.99 ? 500 IHS A O36 1 HETATM 6835 O O42 . IHS C 2 . ? -9.447 9.124 35.871 0.77 28.84 ? 500 IHS A O42 1 HETATM 6836 O O43 . IHS C 2 . ? -7.276 9.462 31.938 0.77 12.32 ? 500 IHS A O43 1 HETATM 6837 O O44 . IHS C 2 . ? -1.074 8.192 34.162 0.77 28.06 ? 500 IHS A O44 1 HETATM 6838 O O45 . IHS C 2 . ? 0.393 10.675 35.829 0.77 27.94 ? 500 IHS A O45 1 HETATM 6839 O O46 . IHS C 2 . ? -2.961 13.775 38.662 0.77 29.41 ? 500 IHS A O46 1 HETATM 6840 C C1 . NAG D 3 . ? 19.681 24.012 37.486 1.00 40.69 ? 1082 NAG A C1 1 HETATM 6841 C C2 . NAG D 3 . ? 19.167 22.895 38.384 1.00 37.61 ? 1082 NAG A C2 1 HETATM 6842 C C3 . NAG D 3 . ? 18.305 23.456 39.522 1.00 39.68 ? 1082 NAG A C3 1 HETATM 6843 C C4 . NAG D 3 . ? 19.043 24.539 40.286 1.00 41.86 ? 1082 NAG A C4 1 HETATM 6844 C C5 . NAG D 3 . ? 19.399 25.579 39.242 1.00 44.15 ? 1082 NAG A C5 1 HETATM 6845 C C6 . NAG D 3 . ? 20.023 26.840 39.837 1.00 47.81 ? 1082 NAG A C6 1 HETATM 6846 C C7 . NAG D 3 . ? 18.769 20.891 36.980 1.00 29.77 ? 1082 NAG A C7 1 HETATM 6847 C C8 . NAG D 3 . ? 17.653 20.088 36.354 1.00 28.53 ? 1082 NAG A C8 1 HETATM 6848 N N2 . NAG D 3 . ? 18.356 21.951 37.663 1.00 32.60 ? 1082 NAG A N2 1 HETATM 6849 O O3 . NAG D 3 . ? 17.985 22.438 40.434 1.00 38.45 ? 1082 NAG A O3 1 HETATM 6850 O O4 . NAG D 3 . ? 18.248 25.065 41.323 1.00 42.44 ? 1082 NAG A O4 1 HETATM 6851 O O5 . NAG D 3 . ? 20.320 24.938 38.360 1.00 43.81 ? 1082 NAG A O5 1 HETATM 6852 O O6 . NAG D 3 . ? 21.324 26.520 40.290 1.00 51.17 ? 1082 NAG A O6 1 HETATM 6853 O O7 . NAG D 3 . ? 19.947 20.562 36.827 1.00 26.77 ? 1082 NAG A O7 1 HETATM 6854 C C1 . NAG E 3 . ? -25.328 7.255 44.725 1.00 32.32 ? 1184 NAG A C1 1 HETATM 6855 C C2 . NAG E 3 . ? -26.822 7.071 44.993 1.00 36.12 ? 1184 NAG A C2 1 HETATM 6856 C C3 . NAG E 3 . ? -27.124 6.997 46.516 1.00 36.44 ? 1184 NAG A C3 1 HETATM 6857 C C4 . NAG E 3 . ? -26.170 5.972 47.140 1.00 38.43 ? 1184 NAG A C4 1 HETATM 6858 C C5 . NAG E 3 . ? -24.735 6.474 46.853 1.00 40.37 ? 1184 NAG A C5 1 HETATM 6859 C C6 . NAG E 3 . ? -23.589 5.815 47.636 1.00 41.07 ? 1184 NAG A C6 1 HETATM 6860 C C7 . NAG E 3 . ? -28.129 7.915 43.071 1.00 31.85 ? 1184 NAG A C7 1 HETATM 6861 C C8 . NAG E 3 . ? -28.887 9.064 42.432 1.00 27.69 ? 1184 NAG A C8 1 HETATM 6862 N N2 . NAG E 3 . ? -27.554 8.112 44.259 1.00 35.44 ? 1184 NAG A N2 1 HETATM 6863 O O3 . NAG E 3 . ? -28.468 6.623 46.826 1.00 40.30 ? 1184 NAG A O3 1 HETATM 6864 O O4 . NAG E 3 . ? -26.459 5.766 48.496 1.00 37.14 ? 1184 NAG A O4 1 HETATM 6865 O O5 . NAG E 3 . ? -24.556 6.314 45.446 1.00 35.63 ? 1184 NAG A O5 1 HETATM 6866 O O6 . NAG E 3 . ? -23.585 4.450 47.316 1.00 45.60 ? 1184 NAG A O6 1 HETATM 6867 O O7 . NAG E 3 . ? -28.073 6.807 42.549 1.00 30.54 ? 1184 NAG A O7 1 HETATM 6868 C C1 . NAG F 3 . ? -27.676 10.627 38.176 1.00 33.47 ? 1316 NAG A C1 1 HETATM 6869 C C2 . NAG F 3 . ? -27.055 11.865 38.866 1.00 36.57 ? 1316 NAG A C2 1 HETATM 6870 C C3 . NAG F 3 . ? -27.799 13.168 38.595 1.00 36.08 ? 1316 NAG A C3 1 HETATM 6871 C C4 . NAG F 3 . ? -28.150 13.341 37.118 1.00 36.48 ? 1316 NAG A C4 1 HETATM 6872 C C5 . NAG F 3 . ? -28.823 12.058 36.566 1.00 38.00 ? 1316 NAG A C5 1 HETATM 6873 C C6 . NAG F 3 . ? -29.178 12.075 35.048 1.00 39.48 ? 1316 NAG A C6 1 HETATM 6874 C C7 . NAG F 3 . ? -25.847 11.213 40.836 1.00 37.51 ? 1316 NAG A C7 1 HETATM 6875 C C8 . NAG F 3 . ? -25.811 10.979 42.335 1.00 36.76 ? 1316 NAG A C8 1 HETATM 6876 N N2 . NAG F 3 . ? -26.977 11.661 40.294 1.00 36.26 ? 1316 NAG A N2 1 HETATM 6877 O O3 . NAG F 3 . ? -26.823 14.121 38.906 1.00 37.56 ? 1316 NAG A O3 1 HETATM 6878 O O4 . NAG F 3 . ? -28.762 14.604 36.830 1.00 31.46 ? 1316 NAG A O4 1 HETATM 6879 O O5 . NAG F 3 . ? -27.964 10.932 36.818 1.00 33.77 ? 1316 NAG A O5 1 HETATM 6880 O O6 . NAG F 3 . ? -28.041 12.315 34.202 1.00 39.57 ? 1316 NAG A O6 1 HETATM 6881 O O7 . NAG F 3 . ? -24.860 10.992 40.143 1.00 38.37 ? 1316 NAG A O7 1 HETATM 6882 C C1 . NAG G 3 . ? -11.414 -12.814 43.746 1.00 22.59 ? 1353 NAG A C1 1 HETATM 6883 C C2 . NAG G 3 . ? -12.806 -13.242 44.145 1.00 22.18 ? 1353 NAG A C2 1 HETATM 6884 C C3 . NAG G 3 . ? -13.319 -12.317 45.240 1.00 23.26 ? 1353 NAG A C3 1 HETATM 6885 C C4 . NAG G 3 . ? -12.341 -12.140 46.408 1.00 24.19 ? 1353 NAG A C4 1 HETATM 6886 C C5 . NAG G 3 . ? -10.964 -11.780 45.836 1.00 26.60 ? 1353 NAG A C5 1 HETATM 6887 C C6 . NAG G 3 . ? -9.731 -11.702 46.759 1.00 31.57 ? 1353 NAG A C6 1 HETATM 6888 C C7 . NAG G 3 . ? -13.914 -14.195 42.287 1.00 26.91 ? 1353 NAG A C7 1 HETATM 6889 C C8 . NAG G 3 . ? -14.793 -14.014 41.089 1.00 28.91 ? 1353 NAG A C8 1 HETATM 6890 N N2 . NAG G 3 . ? -13.652 -13.108 42.996 1.00 25.88 ? 1353 NAG A N2 1 HETATM 6891 O O3 . NAG G 3 . ? -14.624 -12.671 45.693 1.00 25.80 ? 1353 NAG A O3 1 HETATM 6892 O O4 . NAG G 3 . ? -12.941 -11.124 47.212 1.00 24.58 ? 1353 NAG A O4 1 HETATM 6893 O O5 . NAG G 3 . ? -10.631 -12.801 44.927 1.00 25.92 ? 1353 NAG A O5 1 HETATM 6894 O O6 . NAG G 3 . ? -10.200 -11.330 48.030 1.00 32.83 ? 1353 NAG A O6 1 HETATM 6895 O O7 . NAG G 3 . ? -13.466 -15.294 42.597 1.00 29.81 ? 1353 NAG A O7 1 HETATM 6896 C C1 . IHS H 2 . ? 28.097 -31.045 6.224 0.77 28.91 ? 500 IHS B C1 1 HETATM 6897 O O1 . IHS H 2 . ? 29.094 -31.941 5.893 0.77 31.91 ? 500 IHS B O1 1 HETATM 6898 S S1 . IHS H 2 . ? 28.678 -33.284 5.350 0.77 30.92 ? 500 IHS B S1 1 HETATM 6899 C C2 . IHS H 2 . ? 27.953 -30.037 5.087 0.77 28.00 ? 500 IHS B C2 1 HETATM 6900 O O2 . IHS H 2 . ? 28.703 -34.274 6.460 0.77 30.06 ? 500 IHS B O2 1 HETATM 6901 S S2 . IHS H 2 . ? 30.167 -29.566 3.608 0.77 25.73 ? 500 IHS B S2 1 HETATM 6902 C C3 . IHS H 2 . ? 26.988 -28.924 5.513 0.77 23.88 ? 500 IHS B C3 1 HETATM 6903 O O3 . IHS H 2 . ? 29.770 -33.468 4.383 0.77 29.67 ? 500 IHS B O3 1 HETATM 6904 S S3 . IHS H 2 . ? 25.953 -27.776 3.584 0.77 15.28 ? 500 IHS B S3 1 HETATM 6905 C C4 . IHS H 2 . ? 26.912 -28.613 7.003 0.77 27.35 ? 500 IHS B C4 1 HETATM 6906 O O4 . IHS H 2 . ? 27.410 -33.323 4.595 0.77 30.36 ? 500 IHS B O4 1 HETATM 6907 S S4 . IHS H 2 . ? 25.224 -26.891 7.748 0.77 24.34 ? 500 IHS B S4 1 HETATM 6908 C C5 . IHS H 2 . ? 27.057 -29.906 7.794 0.77 29.13 ? 500 IHS B C5 1 HETATM 6909 S S5 . IHS H 2 . ? 25.513 -30.569 9.750 0.77 27.31 ? 500 IHS B S5 1 HETATM 6910 C C6 . IHS H 2 . ? 28.430 -30.465 7.579 0.77 28.90 ? 500 IHS B C6 1 HETATM 6911 S S6 . IHS H 2 . ? 29.792 -31.829 9.414 0.77 29.41 ? 500 IHS B S6 1 HETATM 6912 O O12 . IHS H 2 . ? 29.241 -29.574 4.831 0.77 28.58 ? 500 IHS B O12 1 HETATM 6913 O O13 . IHS H 2 . ? 27.053 -27.785 4.657 0.77 19.34 ? 500 IHS B O13 1 HETATM 6914 O O14 . IHS H 2 . ? 25.564 -28.288 7.246 0.77 27.40 ? 500 IHS B O14 1 HETATM 6915 O O15 . IHS H 2 . ? 26.739 -29.878 9.165 0.77 30.71 ? 500 IHS B O15 1 HETATM 6916 O O16 . IHS H 2 . ? 28.566 -31.568 8.494 0.77 30.95 ? 500 IHS B O16 1 HETATM 6917 O O22 . IHS H 2 . ? 31.493 -29.941 4.171 0.77 25.85 ? 500 IHS B O22 1 HETATM 6918 O O23 . IHS H 2 . ? 26.225 -28.873 2.651 0.77 15.06 ? 500 IHS B O23 1 HETATM 6919 O O24 . IHS H 2 . ? 24.012 -26.423 7.043 0.77 23.88 ? 500 IHS B O24 1 HETATM 6920 O O25 . IHS H 2 . ? 24.353 -29.830 9.255 0.77 29.49 ? 500 IHS B O25 1 HETATM 6921 O O26 . IHS H 2 . ? 29.575 -33.166 9.945 0.77 27.19 ? 500 IHS B O26 1 HETATM 6922 O O32 . IHS H 2 . ? 29.954 -30.478 2.475 0.77 23.85 ? 500 IHS B O32 1 HETATM 6923 O O33 . IHS H 2 . ? 25.891 -26.435 3.011 0.77 17.18 ? 500 IHS B O33 1 HETATM 6924 O O34 . IHS H 2 . ? 26.385 -26.057 7.479 0.77 20.57 ? 500 IHS B O34 1 HETATM 6925 O O35 . IHS H 2 . ? 25.518 -32.009 9.487 0.77 29.77 ? 500 IHS B O35 1 HETATM 6926 O O36 . IHS H 2 . ? 29.734 -30.765 10.448 0.77 28.16 ? 500 IHS B O36 1 HETATM 6927 O O42 . IHS H 2 . ? 30.318 -28.123 3.294 0.77 23.65 ? 500 IHS B O42 1 HETATM 6928 O O43 . IHS H 2 . ? 24.636 -28.169 4.112 0.77 12.76 ? 500 IHS B O43 1 HETATM 6929 O O44 . IHS H 2 . ? 24.883 -27.010 9.201 0.77 26.92 ? 500 IHS B O44 1 HETATM 6930 O O45 . IHS H 2 . ? 25.533 -30.374 11.186 0.77 27.19 ? 500 IHS B O45 1 HETATM 6931 O O46 . IHS H 2 . ? 31.074 -31.770 8.696 0.77 24.30 ? 500 IHS B O46 1 HETATM 6932 C C1 . NAG I 3 . ? 16.320 -43.328 28.456 1.00 39.63 ? 1082 NAG B C1 1 HETATM 6933 C C2 . NAG I 3 . ? 17.366 -42.215 28.473 1.00 39.49 ? 1082 NAG B C2 1 HETATM 6934 C C3 . NAG I 3 . ? 18.783 -42.811 28.482 1.00 39.91 ? 1082 NAG B C3 1 HETATM 6935 C C4 . NAG I 3 . ? 18.971 -43.888 29.559 1.00 40.92 ? 1082 NAG B C4 1 HETATM 6936 C C5 . NAG I 3 . ? 17.801 -44.866 29.414 1.00 43.39 ? 1082 NAG B C5 1 HETATM 6937 C C6 . NAG I 3 . ? 17.846 -46.032 30.405 1.00 45.45 ? 1082 NAG B C6 1 HETATM 6938 C C7 . NAG I 3 . ? 16.472 -40.226 27.267 1.00 33.34 ? 1082 NAG B C7 1 HETATM 6939 C C8 . NAG I 3 . ? 16.627 -39.399 25.997 1.00 31.47 ? 1082 NAG B C8 1 HETATM 6940 N N2 . NAG I 3 . ? 17.264 -41.293 27.348 1.00 36.72 ? 1082 NAG B N2 1 HETATM 6941 O O3 . NAG I 3 . ? 19.720 -41.782 28.663 1.00 41.42 ? 1082 NAG B O3 1 HETATM 6942 O O4 . NAG I 3 . ? 20.203 -44.568 29.401 1.00 39.15 ? 1082 NAG B O4 1 HETATM 6943 O O5 . NAG I 3 . ? 16.580 -44.145 29.574 1.00 42.54 ? 1082 NAG B O5 1 HETATM 6944 O O6 . NAG I 3 . ? 17.282 -45.588 31.627 1.00 46.38 ? 1082 NAG B O6 1 HETATM 6945 O O7 . NAG I 3 . ? 15.651 -39.921 28.138 1.00 30.83 ? 1082 NAG B O7 1 HETATM 6946 C C1 . NAG J 3 . ? 46.834 -26.801 -5.769 1.00 33.92 ? 1184 NAG B C1 1 HETATM 6947 C C2 . NAG J 3 . ? 47.476 -26.813 -7.164 1.00 38.23 ? 1184 NAG B C2 1 HETATM 6948 C C3 . NAG J 3 . ? 48.986 -26.934 -7.158 1.00 40.66 ? 1184 NAG B C3 1 HETATM 6949 C C4 . NAG J 3 . ? 49.447 -25.652 -6.570 1.00 43.11 ? 1184 NAG B C4 1 HETATM 6950 C C5 . NAG J 3 . ? 48.988 -25.742 -5.114 1.00 42.77 ? 1184 NAG B C5 1 HETATM 6951 C C6 . NAG J 3 . ? 49.750 -24.636 -4.383 1.00 44.61 ? 1184 NAG B C6 1 HETATM 6952 C C7 . NAG J 3 . ? 46.713 -27.368 -9.300 1.00 35.37 ? 1184 NAG B C7 1 HETATM 6953 C C8 . NAG J 3 . ? 46.553 -28.426 -10.367 1.00 32.39 ? 1184 NAG B C8 1 HETATM 6954 N N2 . NAG J 3 . ? 47.216 -27.803 -8.171 1.00 36.57 ? 1184 NAG B N2 1 HETATM 6955 O O3 . NAG J 3 . ? 49.431 -26.977 -8.502 1.00 47.62 ? 1184 NAG B O3 1 HETATM 6956 O O4 . NAG J 3 . ? 50.848 -25.514 -6.807 1.00 48.35 ? 1184 NAG B O4 1 HETATM 6957 O O5 . NAG J 3 . ? 47.512 -25.751 -5.025 1.00 38.52 ? 1184 NAG B O5 1 HETATM 6958 O O6 . NAG J 3 . ? 51.075 -24.432 -4.917 1.00 41.44 ? 1184 NAG B O6 1 HETATM 6959 O O7 . NAG J 3 . ? 46.381 -26.168 -9.412 1.00 32.67 ? 1184 NAG B O7 1 HETATM 6960 C C1 . NAG K 3 . ? 42.537 -29.990 -11.302 1.00 35.72 ? 1316 NAG B C1 1 HETATM 6961 C C2 . NAG K 3 . ? 42.771 -31.184 -10.369 1.00 38.21 ? 1316 NAG B C2 1 HETATM 6962 C C3 . NAG K 3 . ? 42.925 -32.473 -11.177 1.00 40.27 ? 1316 NAG B C3 1 HETATM 6963 C C4 . NAG K 3 . ? 41.797 -32.726 -12.212 1.00 41.27 ? 1316 NAG B C4 1 HETATM 6964 C C5 . NAG K 3 . ? 41.462 -31.452 -13.043 1.00 40.64 ? 1316 NAG B C5 1 HETATM 6965 C C6 . NAG K 3 . ? 40.138 -31.598 -13.867 1.00 39.40 ? 1316 NAG B C6 1 HETATM 6966 C C7 . NAG K 3 . ? 43.950 -30.576 -8.250 1.00 39.61 ? 1316 NAG B C7 1 HETATM 6967 C C8 . NAG K 3 . ? 45.268 -30.466 -7.538 1.00 37.13 ? 1316 NAG B C8 1 HETATM 6968 N N2 . NAG K 3 . ? 43.960 -31.016 -9.531 1.00 40.58 ? 1316 NAG B N2 1 HETATM 6969 O O3 . NAG K 3 . ? 42.837 -33.463 -10.197 1.00 41.22 ? 1316 NAG B O3 1 HETATM 6970 O O4 . NAG K 3 . ? 42.085 -33.848 -13.052 1.00 41.31 ? 1316 NAG B O4 1 HETATM 6971 O O5 . NAG K 3 . ? 41.487 -30.230 -12.263 1.00 36.48 ? 1316 NAG B O5 1 HETATM 6972 O O6 . NAG K 3 . ? 38.932 -31.668 -13.094 1.00 37.57 ? 1316 NAG B O6 1 HETATM 6973 O O7 . NAG K 3 . ? 42.926 -30.263 -7.637 1.00 37.69 ? 1316 NAG B O7 1 HETATM 6974 C C1 . NAG L 3 . ? 38.480 -6.702 5.470 1.00 23.06 ? 1353 NAG B C1 1 HETATM 6975 C C2 . NAG L 3 . ? 39.517 -6.229 4.433 1.00 22.85 ? 1353 NAG B C2 1 HETATM 6976 C C3 . NAG L 3 . ? 40.770 -7.087 4.429 1.00 21.52 ? 1353 NAG B C3 1 HETATM 6977 C C4 . NAG L 3 . ? 41.399 -7.199 5.811 1.00 22.90 ? 1353 NAG B C4 1 HETATM 6978 C C5 . NAG L 3 . ? 40.320 -7.581 6.811 1.00 26.50 ? 1353 NAG B C5 1 HETATM 6979 C C6 . NAG L 3 . ? 40.896 -7.560 8.237 1.00 28.87 ? 1353 NAG B C6 1 HETATM 6980 C C7 . NAG L 3 . ? 38.600 -5.197 2.462 1.00 23.95 ? 1353 NAG B C7 1 HETATM 6981 C C8 . NAG L 3 . ? 38.033 -5.375 1.090 1.00 23.73 ? 1353 NAG B C8 1 HETATM 6982 N N2 . NAG L 3 . ? 38.964 -6.297 3.116 1.00 23.59 ? 1353 NAG B N2 1 HETATM 6983 O O3 . NAG L 3 . ? 41.696 -6.511 3.521 1.00 26.90 ? 1353 NAG B O3 1 HETATM 6984 O O4 . NAG L 3 . ? 42.408 -8.214 5.843 1.00 21.95 ? 1353 NAG B O4 1 HETATM 6985 O O5 . NAG L 3 . ? 39.116 -6.791 6.732 1.00 27.10 ? 1353 NAG B O5 1 HETATM 6986 O O6 . NAG L 3 . ? 39.822 -7.765 9.155 1.00 33.46 ? 1353 NAG B O6 1 HETATM 6987 O O7 . NAG L 3 . ? 38.715 -4.079 2.914 1.00 26.30 ? 1353 NAG B O7 1 HETATM 6988 O O . HOH M 4 . ? -5.417 4.486 45.092 1.00 25.90 ? 445 HOH A O 1 HETATM 6989 O O . HOH M 4 . ? 18.638 12.107 44.758 1.00 31.90 ? 446 HOH A O 1 HETATM 6990 O O . HOH M 4 . ? -11.433 -3.940 53.951 1.00 38.49 ? 447 HOH A O 1 HETATM 6991 O O . HOH M 4 . ? -21.165 13.536 23.861 1.00 27.75 ? 448 HOH A O 1 HETATM 6992 O O . HOH M 4 . ? -8.521 -4.038 28.896 1.00 14.64 ? 449 HOH A O 1 HETATM 6993 O O . HOH M 4 . ? -9.412 16.982 25.888 1.00 34.07 ? 450 HOH A O 1 HETATM 6994 O O . HOH M 4 . ? -10.053 -7.694 23.686 1.00 24.34 ? 451 HOH A O 1 HETATM 6995 O O . HOH M 4 . ? -17.455 7.574 9.851 1.00 23.18 ? 452 HOH A O 1 HETATM 6996 O O . HOH M 4 . ? 13.622 0.617 47.928 1.00 34.87 ? 453 HOH A O 1 HETATM 6997 O O . HOH M 4 . ? -21.890 15.579 26.021 1.00 41.45 ? 454 HOH A O 1 HETATM 6998 O O . HOH M 4 . ? -6.787 0.271 18.035 1.00 21.73 ? 455 HOH A O 1 HETATM 6999 O O . HOH M 4 . ? -29.110 -2.012 20.720 1.00 17.17 ? 456 HOH A O 1 HETATM 7000 O O . HOH M 4 . ? -32.162 -1.815 36.392 1.00 26.40 ? 457 HOH A O 1 HETATM 7001 O O . HOH M 4 . ? 9.840 10.815 17.938 1.00 44.61 ? 458 HOH A O 1 HETATM 7002 O O . HOH M 4 . ? -28.296 -7.291 27.916 1.00 24.62 ? 459 HOH A O 1 HETATM 7003 O O . HOH M 4 . ? -26.977 -6.153 39.090 1.00 16.43 ? 460 HOH A O 1 HETATM 7004 O O . HOH M 4 . ? -18.422 0.473 42.890 1.00 14.17 ? 461 HOH A O 1 HETATM 7005 O O . HOH M 4 . ? -12.183 2.226 56.144 1.00 33.29 ? 462 HOH A O 1 HETATM 7006 O O . HOH M 4 . ? -28.998 12.755 42.041 1.00 30.38 ? 463 HOH A O 1 HETATM 7007 O O . HOH M 4 . ? -17.013 -10.036 42.199 1.00 18.41 ? 464 HOH A O 1 HETATM 7008 O O . HOH M 4 . ? 14.370 -1.220 25.048 1.00 31.19 ? 465 HOH A O 1 HETATM 7009 O O . HOH M 4 . ? -26.548 3.958 32.548 1.00 14.53 ? 466 HOH A O 1 HETATM 7010 O O . HOH M 4 . ? -34.659 -2.640 29.071 1.00 18.26 ? 467 HOH A O 1 HETATM 7011 O O . HOH M 4 . ? 19.168 20.745 42.421 1.00 28.22 ? 468 HOH A O 1 HETATM 7012 O O . HOH M 4 . ? -33.220 -3.613 25.476 1.00 27.41 ? 469 HOH A O 1 HETATM 7013 O O . HOH M 4 . ? 1.981 19.246 27.919 1.00 25.95 ? 470 HOH A O 1 HETATM 7014 O O . HOH M 4 . ? 22.358 7.426 29.529 1.00 28.55 ? 471 HOH A O 1 HETATM 7015 O O . HOH M 4 . ? -30.729 -6.707 20.844 1.00 29.40 ? 472 HOH A O 1 HETATM 7016 O O . HOH M 4 . ? 16.647 18.961 40.118 1.00 21.57 ? 473 HOH A O 1 HETATM 7017 O O . HOH M 4 . ? -16.712 -5.151 53.895 1.00 30.81 ? 474 HOH A O 1 HETATM 7018 O O . HOH M 4 . ? 1.699 -8.411 20.790 1.00 32.19 ? 475 HOH A O 1 HETATM 7019 O O . HOH M 4 . ? -17.870 0.842 39.321 1.00 15.09 ? 476 HOH A O 1 HETATM 7020 O O . HOH M 4 . ? -22.789 5.532 36.932 1.00 20.11 ? 477 HOH A O 1 HETATM 7021 O O . HOH M 4 . ? -17.624 11.125 41.269 1.00 30.83 ? 478 HOH A O 1 HETATM 7022 O O . HOH M 4 . ? -12.085 -3.615 47.806 1.00 11.63 ? 479 HOH A O 1 HETATM 7023 O O . HOH M 4 . ? -27.320 -16.293 25.390 1.00 31.24 ? 480 HOH A O 1 HETATM 7024 O O . HOH M 4 . ? -17.207 -16.263 38.906 1.00 26.16 ? 481 HOH A O 1 HETATM 7025 O O . HOH M 4 . ? -9.303 -5.754 19.795 1.00 20.50 ? 482 HOH A O 1 HETATM 7026 O O . HOH M 4 . ? -3.366 20.641 23.067 1.00 40.93 ? 483 HOH A O 1 HETATM 7027 O O . HOH M 4 . ? 21.772 0.078 33.030 1.00 33.17 ? 484 HOH A O 1 HETATM 7028 O O . HOH M 4 . ? -25.585 3.232 44.098 1.00 17.73 ? 485 HOH A O 1 HETATM 7029 O O . HOH M 4 . ? -34.368 -5.223 22.882 1.00 40.96 ? 486 HOH A O 1 HETATM 7030 O O . HOH M 4 . ? -10.756 -7.225 12.910 1.00 27.84 ? 487 HOH A O 1 HETATM 7031 O O . HOH M 4 . ? -25.761 11.611 21.215 1.00 27.71 ? 488 HOH A O 1 HETATM 7032 O O . HOH M 4 . ? -23.377 0.835 27.355 1.00 12.82 ? 489 HOH A O 1 HETATM 7033 O O . HOH M 4 . ? -7.471 6.398 52.867 1.00 33.10 ? 490 HOH A O 1 HETATM 7034 O O . HOH M 4 . ? 14.609 2.472 23.739 1.00 27.46 ? 491 HOH A O 1 HETATM 7035 O O . HOH M 4 . ? -10.366 0.850 22.311 1.00 11.01 ? 492 HOH A O 1 HETATM 7036 O O . HOH M 4 . ? -3.529 4.288 15.743 1.00 27.62 ? 493 HOH A O 1 HETATM 7037 O O . HOH M 4 . ? -19.645 -3.236 51.933 1.00 30.14 ? 494 HOH A O 1 HETATM 7038 O O . HOH M 4 . ? 8.035 -5.075 33.154 1.00 25.87 ? 495 HOH A O 1 HETATM 7039 O O . HOH M 4 . ? -4.089 -8.973 28.386 1.00 19.31 ? 496 HOH A O 1 HETATM 7040 O O . HOH M 4 . ? -10.873 2.154 59.905 1.00 38.13 ? 497 HOH A O 1 HETATM 7041 O O . HOH M 4 . ? -13.947 -14.019 36.833 1.00 21.92 ? 498 HOH A O 1 HETATM 7042 O O . HOH M 4 . ? -12.555 -19.659 23.960 1.00 31.40 ? 499 HOH A O 1 HETATM 7043 O O . HOH M 4 . ? 6.318 7.138 35.892 1.00 36.41 ? 501 HOH A O 1 HETATM 7044 O O . HOH M 4 . ? -12.617 -15.987 29.616 1.00 25.67 ? 502 HOH A O 1 HETATM 7045 O O . HOH M 4 . ? -27.939 1.317 9.063 1.00 37.93 ? 503 HOH A O 1 HETATM 7046 O O . HOH M 4 . ? -34.542 9.139 40.121 1.00 34.61 ? 504 HOH A O 1 HETATM 7047 O O . HOH M 4 . ? -16.311 15.343 21.381 1.00 22.22 ? 505 HOH A O 1 HETATM 7048 O O . HOH M 4 . ? 3.091 -2.582 32.487 1.00 20.43 ? 506 HOH A O 1 HETATM 7049 O O . HOH M 4 . ? -28.096 -9.961 14.124 1.00 25.86 ? 507 HOH A O 1 HETATM 7050 O O . HOH M 4 . ? -16.645 3.927 4.753 1.00 40.68 ? 508 HOH A O 1 HETATM 7051 O O . HOH M 4 . ? 27.160 23.542 25.660 1.00 43.40 ? 509 HOH A O 1 HETATM 7052 O O . HOH M 4 . ? -15.939 -13.841 18.768 1.00 29.37 ? 510 HOH A O 1 HETATM 7053 O O . HOH M 4 . ? -28.966 8.711 12.775 1.00 34.31 ? 511 HOH A O 1 HETATM 7054 O O . HOH M 4 . ? -3.883 2.555 11.616 1.00 31.01 ? 512 HOH A O 1 HETATM 7055 O O . HOH M 4 . ? 11.263 27.228 17.834 1.00 38.16 ? 513 HOH A O 1 HETATM 7056 O O . HOH M 4 . ? 3.986 -6.052 30.808 1.00 31.62 ? 514 HOH A O 1 HETATM 7057 O O . HOH M 4 . ? -2.510 1.596 16.645 1.00 28.22 ? 515 HOH A O 1 HETATM 7058 O O . HOH M 4 . ? -17.732 15.284 33.362 1.00 21.36 ? 516 HOH A O 1 HETATM 7059 O O . HOH M 4 . ? 30.338 11.067 23.885 1.00 40.03 ? 517 HOH A O 1 HETATM 7060 O O . HOH M 4 . ? -24.166 -23.053 25.322 1.00 24.11 ? 518 HOH A O 1 HETATM 7061 O O . HOH M 4 . ? 10.210 -7.495 21.277 1.00 39.82 ? 519 HOH A O 1 HETATM 7062 O O . HOH M 4 . ? -19.507 -12.460 13.789 1.00 19.91 ? 520 HOH A O 1 HETATM 7063 O O . HOH M 4 . ? -7.798 -9.928 43.077 1.00 38.33 ? 521 HOH A O 1 HETATM 7064 O O . HOH M 4 . ? 4.552 -8.378 35.039 1.00 26.53 ? 522 HOH A O 1 HETATM 7065 O O . HOH M 4 . ? -30.193 -19.012 26.580 1.00 32.29 ? 523 HOH A O 1 HETATM 7066 O O . HOH M 4 . ? -18.682 7.904 41.783 1.00 20.62 ? 524 HOH A O 1 HETATM 7067 O O . HOH M 4 . ? -24.570 -0.173 5.857 1.00 35.62 ? 525 HOH A O 1 HETATM 7068 O O . HOH M 4 . ? -4.438 -13.753 37.264 1.00 29.30 ? 526 HOH A O 1 HETATM 7069 O O . HOH M 4 . ? -19.495 -11.867 6.617 1.00 37.75 ? 527 HOH A O 1 HETATM 7070 O O . HOH M 4 . ? -13.867 12.781 18.047 1.00 16.95 ? 528 HOH A O 1 HETATM 7071 O O . HOH M 4 . ? -0.854 6.849 46.945 1.00 37.02 ? 529 HOH A O 1 HETATM 7072 O O . HOH M 4 . ? 5.346 -7.489 32.644 1.00 27.30 ? 530 HOH A O 1 HETATM 7073 O O . HOH M 4 . ? -2.041 -4.049 25.069 1.00 21.19 ? 531 HOH A O 1 HETATM 7074 O O . HOH M 4 . ? -4.559 -13.939 33.095 1.00 41.16 ? 532 HOH A O 1 HETATM 7075 O O . HOH M 4 . ? -6.956 -10.022 17.418 1.00 33.23 ? 533 HOH A O 1 HETATM 7076 O O . HOH M 4 . ? 18.246 16.505 43.484 1.00 32.79 ? 534 HOH A O 1 HETATM 7077 O O . HOH M 4 . ? -25.625 -20.697 40.601 1.00 30.46 ? 535 HOH A O 1 HETATM 7078 O O . HOH M 4 . ? 1.085 -14.593 40.516 1.00 31.61 ? 536 HOH A O 1 HETATM 7079 O O . HOH M 4 . ? -24.998 4.070 36.443 1.00 16.45 ? 537 HOH A O 1 HETATM 7080 O O . HOH M 4 . ? -31.319 0.705 39.090 1.00 30.98 ? 538 HOH A O 1 HETATM 7081 O O . HOH M 4 . ? 6.827 25.171 32.444 1.00 43.81 ? 539 HOH A O 1 HETATM 7082 O O . HOH M 4 . ? -25.821 4.181 20.228 1.00 18.37 ? 540 HOH A O 1 HETATM 7083 O O . HOH M 4 . ? -25.500 1.627 7.790 1.00 34.03 ? 541 HOH A O 1 HETATM 7084 O O . HOH M 4 . ? -10.275 -9.933 19.744 1.00 37.81 ? 542 HOH A O 1 HETATM 7085 O O . HOH M 4 . ? -31.192 10.646 32.532 1.00 38.46 ? 543 HOH A O 1 HETATM 7086 O O . HOH M 4 . ? -19.614 -19.973 40.730 1.00 20.75 ? 544 HOH A O 1 HETATM 7087 O O . HOH M 4 . ? 11.643 -12.858 34.129 1.00 37.26 ? 545 HOH A O 1 HETATM 7088 O O . HOH M 4 . ? -29.953 -1.356 42.178 1.00 25.51 ? 546 HOH A O 1 HETATM 7089 O O . HOH M 4 . ? -19.898 -8.872 5.714 1.00 24.59 ? 547 HOH A O 1 HETATM 7090 O O . HOH M 4 . ? 8.589 -2.067 49.689 1.00 34.67 ? 548 HOH A O 1 HETATM 7091 O O . HOH M 4 . ? -21.351 -2.763 32.492 1.00 21.36 ? 549 HOH A O 1 HETATM 7092 O O . HOH M 4 . ? -29.037 -12.185 20.733 1.00 31.17 ? 550 HOH A O 1 HETATM 7093 O O . HOH M 4 . ? -36.251 -8.682 35.334 1.00 48.46 ? 551 HOH A O 1 HETATM 7094 O O . HOH M 4 . ? 19.627 2.463 41.643 1.00 33.40 ? 552 HOH A O 1 HETATM 7095 O O . HOH M 4 . ? -30.605 -1.860 16.858 1.00 25.38 ? 553 HOH A O 1 HETATM 7096 O O . HOH M 4 . ? 4.672 -11.425 44.191 1.00 46.56 ? 554 HOH A O 1 HETATM 7097 O O . HOH M 4 . ? -14.309 16.176 38.773 1.00 28.14 ? 555 HOH A O 1 HETATM 7098 O O . HOH M 4 . ? -34.722 5.163 24.159 1.00 30.25 ? 556 HOH A O 1 HETATM 7099 O O . HOH M 4 . ? -2.075 4.393 13.303 1.00 22.56 ? 557 HOH A O 1 HETATM 7100 O O . HOH M 4 . ? -13.772 -28.270 29.451 1.00 27.73 ? 558 HOH A O 1 HETATM 7101 O O . HOH M 4 . ? 26.177 16.960 36.832 1.00 43.24 ? 559 HOH A O 1 HETATM 7102 O O . HOH M 4 . ? -22.973 -13.864 16.591 1.00 33.92 ? 560 HOH A O 1 HETATM 7103 O O . HOH M 4 . ? -15.128 11.740 15.641 1.00 24.83 ? 561 HOH A O 1 HETATM 7104 O O . HOH M 4 . ? 3.118 8.151 50.321 1.00 45.24 ? 562 HOH A O 1 HETATM 7105 O O . HOH M 4 . ? 29.890 24.162 26.955 1.00 40.72 ? 563 HOH A O 1 HETATM 7106 O O . HOH M 4 . ? 0.796 -15.341 31.909 1.00 30.23 ? 564 HOH A O 1 HETATM 7107 O O . HOH M 4 . ? -14.178 6.692 44.638 1.00 21.07 ? 565 HOH A O 1 HETATM 7108 O O . HOH M 4 . ? -29.308 -20.059 32.505 1.00 39.50 ? 566 HOH A O 1 HETATM 7109 O O . HOH M 4 . ? -24.986 -1.595 14.091 1.00 15.45 ? 567 HOH A O 1 HETATM 7110 O O . HOH M 4 . ? -25.249 -5.290 44.856 1.00 20.21 ? 568 HOH A O 1 HETATM 7111 O O . HOH M 4 . ? -28.242 -13.805 26.080 1.00 48.04 ? 569 HOH A O 1 HETATM 7112 O O . HOH M 4 . ? -4.991 -13.228 43.553 1.00 25.90 ? 570 HOH A O 1 HETATM 7113 O O . HOH M 4 . ? -16.160 -22.862 40.662 1.00 35.92 ? 571 HOH A O 1 HETATM 7114 O O . HOH M 4 . ? 0.249 7.096 36.408 1.00 38.27 ? 572 HOH A O 1 HETATM 7115 O O . HOH M 4 . ? -28.709 0.555 40.790 1.00 25.92 ? 573 HOH A O 1 HETATM 7116 O O . HOH M 4 . ? -14.131 -10.388 42.437 1.00 26.94 ? 574 HOH A O 1 HETATM 7117 O O . HOH M 4 . ? -27.662 -1.163 29.953 1.00 14.39 ? 575 HOH A O 1 HETATM 7118 O O . HOH M 4 . ? -18.140 -13.100 16.857 1.00 25.93 ? 576 HOH A O 1 HETATM 7119 O O . HOH M 4 . ? 10.527 -6.082 25.745 1.00 46.27 ? 577 HOH A O 1 HETATM 7120 O O . HOH M 4 . ? -29.702 -18.099 20.588 1.00 43.16 ? 578 HOH A O 1 HETATM 7121 O O . HOH M 4 . ? -11.280 -7.060 46.790 1.00 28.63 ? 579 HOH A O 1 HETATM 7122 O O . HOH M 4 . ? -33.594 0.174 7.862 1.00 38.23 ? 580 HOH A O 1 HETATM 7123 O O . HOH M 4 . ? -9.119 14.665 23.014 1.00 33.23 ? 581 HOH A O 1 HETATM 7124 O O . HOH M 4 . ? -26.656 -7.918 48.435 1.00 37.77 ? 582 HOH A O 1 HETATM 7125 O O . HOH M 4 . ? -27.442 -15.497 36.666 1.00 38.75 ? 583 HOH A O 1 HETATM 7126 O O . HOH M 4 . ? -32.824 8.247 33.005 1.00 32.75 ? 584 HOH A O 1 HETATM 7127 O O . HOH M 4 . ? -18.020 12.315 15.282 1.00 13.55 ? 585 HOH A O 1 HETATM 7128 O O . HOH M 4 . ? -11.024 -9.773 15.793 1.00 33.69 ? 586 HOH A O 1 HETATM 7129 O O . HOH M 4 . ? -12.682 -8.611 44.496 1.00 45.98 ? 587 HOH A O 1 HETATM 7130 O O . HOH M 4 . ? 9.489 -3.803 51.386 1.00 32.45 ? 588 HOH A O 1 HETATM 7131 O O . HOH M 4 . ? -26.633 -30.678 21.575 1.00 35.91 ? 589 HOH A O 1 HETATM 7132 O O . HOH M 4 . ? -31.207 -20.007 22.504 1.00 36.15 ? 590 HOH A O 1 HETATM 7133 O O . HOH M 4 . ? -30.555 15.727 35.121 1.00 35.10 ? 591 HOH A O 1 HETATM 7134 O O . HOH M 4 . ? -13.453 5.834 9.837 1.00 29.32 ? 592 HOH A O 1 HETATM 7135 O O . HOH M 4 . ? -10.128 -1.510 28.388 1.00 18.68 ? 593 HOH A O 1 HETATM 7136 O O . HOH M 4 . ? -9.400 15.490 28.203 1.00 30.04 ? 594 HOH A O 1 HETATM 7137 O O . HOH M 4 . ? 9.738 -1.855 14.662 1.00 25.05 ? 595 HOH A O 1 HETATM 7138 O O . HOH M 4 . ? -16.200 -8.825 9.459 1.00 37.10 ? 596 HOH A O 1 HETATM 7139 O O . HOH M 4 . ? -24.053 9.865 37.552 1.00 17.83 ? 597 HOH A O 1 HETATM 7140 O O . HOH M 4 . ? -28.877 -8.032 25.318 1.00 19.16 ? 598 HOH A O 1 HETATM 7141 O O . HOH M 4 . ? 6.791 9.959 36.600 1.00 26.78 ? 599 HOH A O 1 HETATM 7142 O O . HOH M 4 . ? -7.673 -2.097 17.084 1.00 29.43 ? 600 HOH A O 1 HETATM 7143 O O . HOH M 4 . ? -33.229 -0.213 33.194 1.00 27.99 ? 601 HOH A O 1 HETATM 7144 O O . HOH M 4 . ? -34.630 -11.232 27.738 1.00 35.45 ? 602 HOH A O 1 HETATM 7145 O O . HOH M 4 . ? -16.764 -12.642 43.582 1.00 26.54 ? 603 HOH A O 1 HETATM 7146 O O . HOH M 4 . ? 24.289 3.373 34.750 1.00 19.89 ? 604 HOH A O 1 HETATM 7147 O O . HOH M 4 . ? -17.191 -3.643 5.918 1.00 23.98 ? 605 HOH A O 1 HETATM 7148 O O . HOH M 4 . ? -22.831 -11.957 47.019 1.00 31.70 ? 606 HOH A O 1 HETATM 7149 O O . HOH M 4 . ? -13.320 0.558 7.792 1.00 35.04 ? 607 HOH A O 1 HETATM 7150 O O . HOH M 4 . ? 5.042 -5.102 34.432 1.00 21.91 ? 608 HOH A O 1 HETATM 7151 O O . HOH M 4 . ? -12.274 -2.840 19.628 1.00 17.88 ? 609 HOH A O 1 HETATM 7152 O O . HOH M 4 . ? -2.274 1.241 19.339 1.00 18.47 ? 610 HOH A O 1 HETATM 7153 O O . HOH M 4 . ? -28.506 5.116 18.394 1.00 30.47 ? 611 HOH A O 1 HETATM 7154 O O . HOH M 4 . ? -32.344 1.469 14.592 1.00 37.66 ? 612 HOH A O 1 HETATM 7155 O O . HOH M 4 . ? 18.687 9.923 22.456 1.00 32.13 ? 613 HOH A O 1 HETATM 7156 O O . HOH M 4 . ? 14.565 24.808 18.445 1.00 40.70 ? 614 HOH A O 1 HETATM 7157 O O . HOH M 4 . ? -34.166 4.331 40.952 1.00 44.82 ? 615 HOH A O 1 HETATM 7158 O O . HOH M 4 . ? -4.670 0.212 15.922 1.00 24.05 ? 616 HOH A O 1 HETATM 7159 O O . HOH M 4 . ? 0.105 13.312 32.068 1.00 30.43 ? 617 HOH A O 1 HETATM 7160 O O . HOH M 4 . ? -0.873 -10.511 19.042 1.00 34.44 ? 618 HOH A O 1 HETATM 7161 O O . HOH M 4 . ? -22.378 10.489 19.827 1.00 22.24 ? 619 HOH A O 1 HETATM 7162 O O . HOH M 4 . ? -23.861 -15.393 10.957 1.00 32.44 ? 620 HOH A O 1 HETATM 7163 O O . HOH M 4 . ? 9.746 20.318 36.818 1.00 26.80 ? 621 HOH A O 1 HETATM 7164 O O . HOH M 4 . ? 4.470 -5.290 28.166 1.00 34.70 ? 622 HOH A O 1 HETATM 7165 O O . HOH M 4 . ? 15.624 12.426 44.813 1.00 23.06 ? 623 HOH A O 1 HETATM 7166 O O . HOH M 4 . ? -19.862 10.170 48.719 1.00 27.03 ? 624 HOH A O 1 HETATM 7167 O O . HOH M 4 . ? -28.974 0.892 20.810 1.00 24.13 ? 625 HOH A O 1 HETATM 7168 O O . HOH M 4 . ? 2.107 11.747 32.410 1.00 34.16 ? 626 HOH A O 1 HETATM 7169 O O . HOH M 4 . ? 14.042 -6.507 40.289 1.00 43.97 ? 627 HOH A O 1 HETATM 7170 O O . HOH M 4 . ? -4.888 -4.638 9.946 1.00 37.00 ? 628 HOH A O 1 HETATM 7171 O O . HOH M 4 . ? -16.047 10.362 38.467 1.00 30.47 ? 629 HOH A O 1 HETATM 7172 O O . HOH M 4 . ? -10.605 4.486 57.408 1.00 34.75 ? 630 HOH A O 1 HETATM 7173 O O . HOH N 4 . ? 10.771 -21.278 -1.883 1.00 30.25 ? 445 HOH B O 1 HETATM 7174 O O . HOH N 4 . ? 23.706 -9.250 4.681 1.00 27.14 ? 446 HOH B O 1 HETATM 7175 O O . HOH N 4 . ? 14.281 -19.639 -4.420 1.00 15.87 ? 447 HOH B O 1 HETATM 7176 O O . HOH N 4 . ? 24.418 -15.105 -0.221 1.00 17.79 ? 448 HOH B O 1 HETATM 7177 O O . HOH N 4 . ? 43.155 -11.633 -12.617 1.00 28.92 ? 449 HOH B O 1 HETATM 7178 O O . HOH N 4 . ? 38.934 -9.131 2.490 1.00 25.32 ? 450 HOH B O 1 HETATM 7179 O O . HOH N 4 . ? 22.090 -36.041 -2.548 1.00 34.49 ? 451 HOH B O 1 HETATM 7180 O O . HOH N 4 . ? 13.282 -26.700 -18.157 1.00 18.64 ? 452 HOH B O 1 HETATM 7181 O O . HOH N 4 . ? 43.330 -17.734 -16.036 1.00 21.73 ? 453 HOH B O 1 HETATM 7182 O O . HOH N 4 . ? 0.051 -27.026 12.980 1.00 33.68 ? 454 HOH B O 1 HETATM 7183 O O . HOH N 4 . ? 9.004 -17.869 17.434 1.00 30.69 ? 455 HOH B O 1 HETATM 7184 O O . HOH N 4 . ? 12.002 -10.421 -16.666 1.00 36.55 ? 456 HOH B O 1 HETATM 7185 O O . HOH N 4 . ? 37.106 -23.430 -13.351 1.00 26.54 ? 457 HOH B O 1 HETATM 7186 O O . HOH N 4 . ? 15.523 -21.195 -25.612 1.00 28.61 ? 458 HOH B O 1 HETATM 7187 O O . HOH N 4 . ? 41.377 -19.863 -0.944 1.00 14.48 ? 459 HOH B O 1 HETATM 7188 O O . HOH N 4 . ? 20.911 -11.651 -4.208 1.00 18.03 ? 460 HOH B O 1 HETATM 7189 O O . HOH N 4 . ? 15.141 -9.344 -8.955 1.00 33.90 ? 461 HOH B O 1 HETATM 7190 O O . HOH N 4 . ? 2.806 -43.369 13.273 1.00 36.86 ? 462 HOH B O 1 HETATM 7191 O O . HOH N 4 . ? 24.981 -21.139 -27.924 1.00 26.91 ? 463 HOH B O 1 HETATM 7192 O O . HOH N 4 . ? 5.739 -30.207 9.729 1.00 24.62 ? 464 HOH B O 1 HETATM 7193 O O . HOH N 4 . ? 35.487 -18.100 -15.752 1.00 20.81 ? 465 HOH B O 1 HETATM 7194 O O . HOH N 4 . ? 7.792 -21.587 -9.814 1.00 27.84 ? 466 HOH B O 1 HETATM 7195 O O . HOH N 4 . ? 30.926 -18.768 -21.861 1.00 15.83 ? 467 HOH B O 1 HETATM 7196 O O . HOH N 4 . ? 45.118 -19.918 -10.793 1.00 21.05 ? 468 HOH B O 1 HETATM 7197 O O . HOH N 4 . ? 28.577 -1.452 -22.919 1.00 39.42 ? 469 HOH B O 1 HETATM 7198 O O . HOH N 4 . ? 33.972 -5.297 -0.445 1.00 20.32 ? 470 HOH B O 1 HETATM 7199 O O . HOH N 4 . ? 24.712 -4.590 -21.710 1.00 35.95 ? 471 HOH B O 1 HETATM 7200 O O . HOH N 4 . ? 39.575 -30.572 -1.014 1.00 31.35 ? 472 HOH B O 1 HETATM 7201 O O . HOH N 4 . ? 13.628 -3.591 -2.077 1.00 46.60 ? 473 HOH B O 1 HETATM 7202 O O . HOH N 4 . ? 46.315 -22.794 -6.294 1.00 13.40 ? 474 HOH B O 1 HETATM 7203 O O . HOH N 4 . ? 28.280 -7.269 -21.493 1.00 36.60 ? 475 HOH B O 1 HETATM 7204 O O . HOH N 4 . ? 19.937 -20.289 -5.167 1.00 15.87 ? 476 HOH B O 1 HETATM 7205 O O . HOH N 4 . ? 31.052 -20.197 -13.498 1.00 13.57 ? 477 HOH B O 1 HETATM 7206 O O . HOH N 4 . ? 26.521 -23.700 -19.347 1.00 20.25 ? 478 HOH B O 1 HETATM 7207 O O . HOH N 4 . ? 17.809 -20.605 -26.977 1.00 24.67 ? 479 HOH B O 1 HETATM 7208 O O . HOH N 4 . ? 21.120 -40.356 30.625 1.00 33.72 ? 480 HOH B O 1 HETATM 7209 O O . HOH N 4 . ? 26.859 -33.102 -13.581 1.00 40.25 ? 481 HOH B O 1 HETATM 7210 O O . HOH N 4 . ? 29.537 -5.504 7.805 1.00 19.80 ? 482 HOH B O 1 HETATM 7211 O O . HOH N 4 . ? 42.215 -15.702 7.157 1.00 22.79 ? 483 HOH B O 1 HETATM 7212 O O . HOH N 4 . ? 17.590 -9.407 -6.288 1.00 25.89 ? 484 HOH B O 1 HETATM 7213 O O . HOH N 4 . ? 37.195 -31.315 0.158 1.00 27.89 ? 485 HOH B O 1 HETATM 7214 O O . HOH N 4 . ? 47.596 -16.640 -4.197 1.00 23.47 ? 486 HOH B O 1 HETATM 7215 O O . HOH N 4 . ? 30.323 4.399 -19.010 1.00 35.70 ? 487 HOH B O 1 HETATM 7216 O O . HOH N 4 . ? 38.787 -25.055 -7.875 1.00 23.64 ? 488 HOH B O 1 HETATM 7217 O O . HOH N 4 . ? 14.794 -29.204 5.002 1.00 44.31 ? 489 HOH B O 1 HETATM 7218 O O . HOH N 4 . ? 49.593 -14.298 6.835 1.00 35.30 ? 490 HOH B O 1 HETATM 7219 O O . HOH N 4 . ? 1.385 -23.830 11.837 1.00 39.16 ? 491 HOH B O 1 HETATM 7220 O O . HOH N 4 . ? 40.187 -9.464 -0.298 1.00 19.45 ? 492 HOH B O 1 HETATM 7221 O O . HOH N 4 . ? 38.200 -19.993 -2.397 1.00 23.14 ? 493 HOH B O 1 HETATM 7222 O O . HOH N 4 . ? 49.893 -16.399 2.786 1.00 29.22 ? 494 HOH B O 1 HETATM 7223 O O . HOH N 4 . ? 9.514 -20.996 29.016 1.00 37.28 ? 495 HOH B O 1 HETATM 7224 O O . HOH N 4 . ? 20.076 -21.551 30.756 1.00 31.87 ? 496 HOH B O 1 HETATM 7225 O O . HOH N 4 . ? 22.464 -36.767 -12.752 1.00 43.98 ? 497 HOH B O 1 HETATM 7226 O O . HOH N 4 . ? 37.692 -3.173 -2.014 1.00 24.91 ? 498 HOH B O 1 HETATM 7227 O O . HOH N 4 . ? 27.166 -3.312 -3.237 1.00 21.81 ? 499 HOH B O 1 HETATM 7228 O O . HOH N 4 . ? 39.619 -23.361 -9.967 1.00 18.29 ? 501 HOH B O 1 HETATM 7229 O O . HOH N 4 . ? 40.731 -26.237 3.637 1.00 27.66 ? 502 HOH B O 1 HETATM 7230 O O . HOH N 4 . ? 29.611 -12.795 -23.342 1.00 31.64 ? 503 HOH B O 1 HETATM 7231 O O . HOH N 4 . ? 29.751 6.094 -8.390 1.00 33.07 ? 504 HOH B O 1 HETATM 7232 O O . HOH N 4 . ? 30.529 -25.567 15.961 1.00 42.64 ? 505 HOH B O 1 HETATM 7233 O O . HOH N 4 . ? 26.322 -17.441 -25.080 1.00 20.74 ? 506 HOH B O 1 HETATM 7234 O O . HOH N 4 . ? 19.480 -44.335 14.550 1.00 39.30 ? 507 HOH B O 1 HETATM 7235 O O . HOH N 4 . ? 1.177 -32.030 20.551 1.00 33.25 ? 508 HOH B O 1 HETATM 7236 O O . HOH N 4 . ? 28.757 -19.712 29.127 1.00 47.02 ? 509 HOH B O 1 HETATM 7237 O O . HOH N 4 . ? 3.612 -32.942 7.869 1.00 30.38 ? 510 HOH B O 1 HETATM 7238 O O . HOH N 4 . ? 35.696 -26.071 15.745 1.00 34.25 ? 511 HOH B O 1 HETATM 7239 O O . HOH N 4 . ? 9.355 -15.870 -19.573 1.00 24.61 ? 512 HOH B O 1 HETATM 7240 O O . HOH N 4 . ? 4.752 -25.618 15.949 1.00 36.51 ? 513 HOH B O 1 HETATM 7241 O O . HOH N 4 . ? 17.641 -15.177 3.358 1.00 14.22 ? 514 HOH B O 1 HETATM 7242 O O . HOH N 4 . ? 20.770 -17.632 -21.921 1.00 20.84 ? 515 HOH B O 1 HETATM 7243 O O . HOH N 4 . ? 47.464 -7.440 -2.721 1.00 41.14 ? 516 HOH B O 1 HETATM 7244 O O . HOH N 4 . ? 7.294 -6.853 -0.768 1.00 41.28 ? 517 HOH B O 1 HETATM 7245 O O . HOH N 4 . ? 8.574 -26.727 26.324 1.00 27.09 ? 518 HOH B O 1 HETATM 7246 O O . HOH N 4 . ? 41.149 -19.215 -18.872 1.00 34.06 ? 519 HOH B O 1 HETATM 7247 O O . HOH N 4 . ? 43.977 -17.470 -18.675 1.00 31.07 ? 520 HOH B O 1 HETATM 7248 O O . HOH N 4 . ? 43.988 -25.088 13.847 1.00 28.27 ? 521 HOH B O 1 HETATM 7249 O O . HOH N 4 . ? 7.195 -21.684 -25.074 1.00 29.57 ? 522 HOH B O 1 HETATM 7250 O O . HOH N 4 . ? 44.405 -32.184 1.774 1.00 40.81 ? 523 HOH B O 1 HETATM 7251 O O . HOH N 4 . ? 22.154 0.130 -5.896 1.00 22.72 ? 524 HOH B O 1 HETATM 7252 O O . HOH N 4 . ? 46.391 -30.605 -4.112 1.00 50.45 ? 525 HOH B O 1 HETATM 7253 O O . HOH N 4 . ? 40.701 -27.268 -1.801 1.00 21.63 ? 526 HOH B O 1 HETATM 7254 O O . HOH N 4 . ? 38.537 -16.604 -22.247 1.00 23.62 ? 527 HOH B O 1 HETATM 7255 O O . HOH N 4 . ? 5.472 -34.176 11.608 1.00 29.61 ? 528 HOH B O 1 HETATM 7256 O O . HOH N 4 . ? 22.409 -16.065 25.914 1.00 46.60 ? 529 HOH B O 1 HETATM 7257 O O . HOH N 4 . ? 27.102 2.924 0.435 1.00 32.98 ? 530 HOH B O 1 HETATM 7258 O O . HOH N 4 . ? 19.376 -14.207 16.020 1.00 30.27 ? 531 HOH B O 1 HETATM 7259 O O . HOH N 4 . ? 10.345 -5.367 6.925 1.00 50.63 ? 532 HOH B O 1 HETATM 7260 O O . HOH N 4 . ? 43.739 -9.068 -12.683 1.00 26.86 ? 533 HOH B O 1 HETATM 7261 O O . HOH N 4 . ? 12.200 -2.890 6.740 1.00 45.14 ? 534 HOH B O 1 HETATM 7262 O O . HOH N 4 . ? 37.744 -2.684 5.084 1.00 28.92 ? 535 HOH B O 1 HETATM 7263 O O . HOH N 4 . ? 23.402 -35.305 -8.237 1.00 24.21 ? 536 HOH B O 1 HETATM 7264 O O . HOH N 4 . ? 17.614 -7.130 -17.768 1.00 24.14 ? 537 HOH B O 1 HETATM 7265 O O . HOH N 4 . ? 17.038 -13.626 -5.557 1.00 16.83 ? 538 HOH B O 1 HETATM 7266 O O . HOH N 4 . ? 28.908 -7.774 15.895 1.00 26.61 ? 539 HOH B O 1 HETATM 7267 O O . HOH N 4 . ? 11.982 -12.143 -10.503 1.00 40.15 ? 540 HOH B O 1 HETATM 7268 O O . HOH N 4 . ? 12.730 -24.434 33.189 1.00 43.58 ? 541 HOH B O 1 HETATM 7269 O O . HOH N 4 . ? 21.323 -16.563 11.726 1.00 16.61 ? 542 HOH B O 1 HETATM 7270 O O . HOH N 4 . ? 11.793 -7.588 -20.871 1.00 31.88 ? 543 HOH B O 1 HETATM 7271 O O . HOH N 4 . ? 8.967 -19.952 -15.331 1.00 41.74 ? 544 HOH B O 1 HETATM 7272 O O . HOH N 4 . ? 14.915 -20.278 27.976 1.00 21.37 ? 545 HOH B O 1 HETATM 7273 O O . HOH N 4 . ? 4.060 -28.995 32.746 1.00 31.46 ? 546 HOH B O 1 HETATM 7274 O O . HOH N 4 . ? 21.688 -5.400 -18.887 1.00 33.25 ? 547 HOH B O 1 HETATM 7275 O O . HOH N 4 . ? 50.505 -12.801 10.232 1.00 33.38 ? 548 HOH B O 1 HETATM 7276 O O . HOH N 4 . ? 43.819 -11.566 -8.106 1.00 26.56 ? 549 HOH B O 1 HETATM 7277 O O . HOH N 4 . ? 32.011 -3.829 -17.589 1.00 46.81 ? 550 HOH B O 1 HETATM 7278 O O . HOH N 4 . ? 41.286 -3.774 -11.763 1.00 33.62 ? 551 HOH B O 1 HETATM 7279 O O . HOH N 4 . ? 45.435 -9.634 -9.126 1.00 34.88 ? 552 HOH B O 1 HETATM 7280 O O . HOH N 4 . ? 17.383 -19.944 27.303 1.00 24.85 ? 553 HOH B O 1 HETATM 7281 O O . HOH N 4 . ? 9.974 -9.955 -5.418 1.00 30.42 ? 554 HOH B O 1 HETATM 7282 O O . HOH N 4 . ? 47.970 -21.212 -13.475 1.00 34.72 ? 555 HOH B O 1 HETATM 7283 O O . HOH N 4 . ? 24.326 6.105 -11.275 1.00 24.11 ? 556 HOH B O 1 HETATM 7284 O O . HOH N 4 . ? 28.643 -3.342 4.312 1.00 27.79 ? 557 HOH B O 1 HETATM 7285 O O . HOH N 4 . ? 4.659 -21.027 20.544 1.00 34.79 ? 558 HOH B O 1 HETATM 7286 O O . HOH N 4 . ? 5.022 -28.878 7.462 1.00 33.92 ? 559 HOH B O 1 HETATM 7287 O O . HOH N 4 . ? 30.024 3.444 -15.353 1.00 28.30 ? 560 HOH B O 1 HETATM 7288 O O . HOH N 4 . ? 3.041 -37.687 15.686 1.00 40.47 ? 561 HOH B O 1 HETATM 7289 O O . HOH N 4 . ? 7.711 -21.731 16.902 1.00 26.53 ? 562 HOH B O 1 HETATM 7290 O O . HOH N 4 . ? 31.482 -26.713 -21.236 1.00 25.13 ? 563 HOH B O 1 HETATM 7291 O O . HOH N 4 . ? 6.184 -35.296 9.330 1.00 36.67 ? 564 HOH B O 1 HETATM 7292 O O . HOH N 4 . ? 15.377 -7.467 -16.404 1.00 24.53 ? 565 HOH B O 1 HETATM 7293 O O . HOH N 4 . ? 17.515 -44.686 20.539 1.00 40.31 ? 566 HOH B O 1 HETATM 7294 O O . HOH N 4 . ? 17.515 -18.234 32.685 1.00 28.20 ? 567 HOH B O 1 HETATM 7295 O O . HOH N 4 . ? 42.463 -27.669 20.419 1.00 36.66 ? 568 HOH B O 1 HETATM 7296 O O . HOH N 4 . ? 28.570 -17.367 -21.909 1.00 27.32 ? 569 HOH B O 1 HETATM 7297 O O . HOH N 4 . ? 2.118 -34.188 14.411 1.00 27.13 ? 570 HOH B O 1 HETATM 7298 O O . HOH N 4 . ? 4.618 -38.336 12.403 1.00 23.88 ? 571 HOH B O 1 HETATM 7299 O O . HOH N 4 . ? 5.585 -17.611 -24.784 1.00 34.25 ? 572 HOH B O 1 HETATM 7300 O O . HOH N 4 . ? 41.899 -35.006 -15.542 1.00 31.81 ? 574 HOH B O 1 HETATM 7301 O O . HOH N 4 . ? 19.111 -29.227 -15.778 1.00 12.05 ? 575 HOH B O 1 HETATM 7302 O O . HOH N 4 . ? 11.307 -25.216 -14.579 1.00 22.82 ? 576 HOH B O 1 HETATM 7303 O O . HOH N 4 . ? 36.329 -23.818 11.349 1.00 28.06 ? 577 HOH B O 1 HETATM 7304 O O . HOH N 4 . ? 24.908 -17.828 -1.716 1.00 20.52 ? 578 HOH B O 1 HETATM 7305 O O . HOH N 4 . ? 36.740 -23.852 14.061 1.00 24.28 ? 579 HOH B O 1 HETATM 7306 O O . HOH N 4 . ? 34.695 -15.969 -23.068 1.00 28.66 ? 580 HOH B O 1 HETATM 7307 O O . HOH N 4 . ? 50.298 -11.707 -5.263 1.00 42.75 ? 581 HOH B O 1 HETATM 7308 O O . HOH N 4 . ? 4.151 -28.794 19.618 1.00 26.36 ? 582 HOH B O 1 HETATM 7309 O O . HOH N 4 . ? 15.177 -22.845 -23.400 1.00 33.48 ? 583 HOH B O 1 HETATM 7310 O O . HOH N 4 . ? 23.934 -29.937 -16.558 1.00 19.28 ? 584 HOH B O 1 HETATM 7311 O O . HOH N 4 . ? 24.145 -34.994 -1.120 1.00 20.16 ? 585 HOH B O 1 HETATM 7312 O O . HOH N 4 . ? 40.030 -29.223 -8.548 1.00 22.66 ? 586 HOH B O 1 HETATM 7313 O O . HOH N 4 . ? 41.877 -21.615 11.649 1.00 30.83 ? 587 HOH B O 1 HETATM 7314 O O . HOH N 4 . ? 18.660 -16.534 -8.401 1.00 14.15 ? 588 HOH B O 1 HETATM 7315 O O . HOH N 4 . ? 11.569 -27.160 -21.058 1.00 37.33 ? 589 HOH B O 1 HETATM 7316 O O . HOH N 4 . ? 32.242 -11.151 -19.117 1.00 16.67 ? 590 HOH B O 1 HETATM 7317 O O . HOH N 4 . ? 47.275 -18.118 -11.158 1.00 21.88 ? 591 HOH B O 1 HETATM 7318 O O . HOH N 4 . ? 22.801 -29.447 16.562 1.00 31.64 ? 592 HOH B O 1 HETATM 7319 O O . HOH N 4 . ? 43.016 -13.246 -10.244 1.00 20.14 ? 593 HOH B O 1 HETATM 7320 O O . HOH N 4 . ? 14.058 -17.378 -5.876 1.00 26.98 ? 594 HOH B O 1 HETATM 7321 O O . HOH N 4 . ? 19.939 -3.003 19.308 1.00 38.28 ? 595 HOH B O 1 HETATM 7322 O O . HOH N 4 . ? 40.648 0.597 -3.030 1.00 25.39 ? 596 HOH B O 1 HETATM 7323 O O . HOH N 4 . ? 12.929 -20.652 0.161 1.00 21.22 ? 597 HOH B O 1 HETATM 7324 O O . HOH N 4 . ? 22.372 -10.944 14.297 1.00 30.07 ? 598 HOH B O 1 HETATM 7325 O O . HOH N 4 . ? 34.421 -9.246 5.165 1.00 20.00 ? 599 HOH B O 1 HETATM 7326 O O . HOH N 4 . ? 45.494 -18.192 -14.856 1.00 32.09 ? 600 HOH B O 1 HETATM 7327 O O . HOH N 4 . ? 36.476 -29.591 -1.565 1.00 28.18 ? 601 HOH B O 1 HETATM 7328 O O . HOH N 4 . ? 34.033 -12.131 -17.383 1.00 28.72 ? 602 HOH B O 1 HETATM 7329 O O . HOH N 4 . ? 40.008 -32.568 3.409 1.00 30.94 ? 603 HOH B O 1 HETATM 7330 O O . HOH N 4 . ? 17.400 -27.838 -17.900 1.00 22.09 ? 604 HOH B O 1 HETATM 7331 O O . HOH N 4 . ? 25.871 -39.028 -3.503 1.00 23.31 ? 605 HOH B O 1 HETATM 7332 O O . HOH N 4 . ? 20.099 -38.179 27.344 1.00 23.52 ? 606 HOH B O 1 HETATM 7333 O O . HOH N 4 . ? 16.828 -13.771 10.523 1.00 32.21 ? 607 HOH B O 1 HETATM 7334 O O . HOH N 4 . ? 10.852 -23.940 -3.041 1.00 31.62 ? 608 HOH B O 1 HETATM 7335 O O . HOH N 4 . ? 31.302 -8.529 -18.908 1.00 25.72 ? 609 HOH B O 1 HETATM 7336 O O . HOH N 4 . ? 33.213 -34.770 -5.634 1.00 31.87 ? 610 HOH B O 1 HETATM 7337 O O . HOH N 4 . ? 18.464 -31.896 -10.352 1.00 21.19 ? 611 HOH B O 1 HETATM 7338 O O . HOH N 4 . ? 38.191 -30.806 -9.786 1.00 20.85 ? 612 HOH B O 1 HETATM 7339 O O . HOH N 4 . ? 21.836 -4.450 -21.768 1.00 37.20 ? 613 HOH B O 1 HETATM 7340 O O . HOH N 4 . ? 13.901 -19.591 -25.914 1.00 32.55 ? 614 HOH B O 1 HETATM 7341 O O . HOH N 4 . ? 34.171 -25.386 11.686 1.00 38.19 ? 615 HOH B O 1 HETATM 7342 O O . HOH N 4 . ? 5.240 -17.264 -6.833 1.00 28.99 ? 616 HOH B O 1 HETATM 7343 O O . HOH N 4 . ? 18.979 -19.019 30.180 1.00 35.08 ? 617 HOH B O 1 HETATM 7344 O O . HOH N 4 . ? 22.109 -26.669 15.892 1.00 31.96 ? 618 HOH B O 1 HETATM 7345 O O . HOH N 4 . ? 39.940 -13.809 10.092 1.00 19.13 ? 619 HOH B O 1 HETATM 7346 O O . HOH N 4 . ? 9.979 -30.803 0.806 1.00 27.81 ? 620 HOH B O 1 HETATM 7347 O O . HOH N 4 . ? 11.653 -19.519 -3.810 1.00 27.54 ? 621 HOH B O 1 HETATM 7348 O O . HOH N 4 . ? 27.151 8.846 -4.054 1.00 28.64 ? 622 HOH B O 1 HETATM 7349 O O . HOH N 4 . ? 16.881 -30.976 -12.705 1.00 27.77 ? 623 HOH B O 1 HETATM 7350 O O . HOH N 4 . ? 38.425 4.563 -9.900 1.00 27.94 ? 624 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ALA 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 ARG 3 3 ? ? ? A . n A 1 4 ASN 4 4 ? ? ? A . n A 1 5 GLN 5 5 ? ? ? A . n A 1 6 SER 6 6 ? ? ? A . n A 1 7 SER 7 7 7 SER SER A . n A 1 8 CYS 8 8 8 CYS CYS A . n A 1 9 ASP 9 9 9 ASP ASP A . n A 1 10 THR 10 10 10 THR THR A . n A 1 11 VAL 11 11 11 VAL VAL A . n A 1 12 ASP 12 12 12 ASP ASP A . n A 1 13 GLN 13 13 13 GLN GLN A . n A 1 14 GLY 14 14 14 GLY GLY A . n A 1 15 TYR 15 15 15 TYR TYR A . n A 1 16 GLN 16 16 16 GLN GLN A . n A 1 17 CYS 17 17 17 CYS CYS A . n A 1 18 PHE 18 18 18 PHE PHE A . n A 1 19 SER 19 19 19 SER SER A . n A 1 20 GLU 20 20 20 GLU GLU A . n A 1 21 THR 21 21 21 THR THR A . n A 1 22 SER 22 22 22 SER SER A . n A 1 23 HIS 23 23 23 HIS HIS A . n A 1 24 LEU 24 24 24 LEU LEU A . n A 1 25 TRP 25 25 25 TRP TRP A . n A 1 26 GLY 26 26 26 GLY GLY A . n A 1 27 GLN 27 27 27 GLN GLN A . n A 1 28 TYR 28 28 28 TYR TYR A . n A 1 29 ALA 29 29 29 ALA ALA A . n A 1 30 PRO 30 30 30 PRO PRO A . n A 1 31 PHE 31 31 31 PHE PHE A . n A 1 32 PHE 32 32 32 PHE PHE A . n A 1 33 SER 33 33 33 SER SER A . n A 1 34 LEU 34 34 34 LEU LEU A . n A 1 35 ALA 35 35 35 ALA ALA A . n A 1 36 ASN 36 36 36 ASN ASN A . n A 1 37 GLU 37 37 37 GLU GLU A . n A 1 38 SER 38 38 38 SER SER A . n A 1 39 VAL 39 39 39 VAL VAL A . n A 1 40 ILE 40 40 40 ILE ILE A . n A 1 41 SER 41 41 41 SER SER A . n A 1 42 PRO 42 42 42 PRO PRO A . n A 1 43 GLU 43 43 43 GLU GLU A . n A 1 44 VAL 44 44 44 VAL VAL A . n A 1 45 PRO 45 45 45 PRO PRO A . n A 1 46 ALA 46 46 46 ALA ALA A . n A 1 47 GLY 47 47 47 GLY GLY A . n A 1 48 CYS 48 48 48 CYS CYS A . n A 1 49 ARG 49 49 49 ARG ARG A . n A 1 50 VAL 50 50 50 VAL VAL A . n A 1 51 THR 51 51 51 THR THR A . n A 1 52 PHE 52 52 52 PHE PHE A . n A 1 53 ALA 53 53 53 ALA ALA A . n A 1 54 GLN 54 54 54 GLN GLN A . n A 1 55 VAL 55 55 55 VAL VAL A . n A 1 56 LEU 56 56 56 LEU LEU A . n A 1 57 SER 57 57 57 SER SER A . n A 1 58 ARG 58 58 58 ARG ARG A . n A 1 59 HIS 59 59 59 HIS HIS A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 ALA 61 61 61 ALA ALA A . n A 1 62 ARG 62 62 62 ARG ARG A . n A 1 63 TYR 63 63 63 TYR TYR A . n A 1 64 PRO 64 64 64 PRO PRO A . n A 1 65 THR 65 65 65 THR THR A . n A 1 66 ASP 66 66 66 ASP ASP A . n A 1 67 SER 67 67 67 SER SER A . n A 1 68 LYS 68 68 68 LYS LYS A . n A 1 69 GLY 69 69 69 GLY GLY A . n A 1 70 LYS 70 70 70 LYS LYS A . n A 1 71 LYS 71 71 71 LYS LYS A . n A 1 72 TYR 72 72 72 TYR TYR A . n A 1 73 SER 73 73 73 SER SER A . n A 1 74 ALA 74 74 74 ALA ALA A . n A 1 75 LEU 75 75 75 LEU LEU A . n A 1 76 ILE 76 76 76 ILE ILE A . n A 1 77 GLU 77 77 77 GLU GLU A . n A 1 78 GLU 78 78 78 GLU GLU A . n A 1 79 ILE 79 79 79 ILE ILE A . n A 1 80 GLN 80 80 80 GLN GLN A . n A 1 81 GLN 81 81 81 GLN GLN A . n A 1 82 ASN 82 82 82 ASN ASN A . n A 1 83 ALA 83 83 83 ALA ALA A . n A 1 84 THR 84 84 84 THR THR A . n A 1 85 THR 85 85 85 THR THR A . n A 1 86 PHE 86 86 86 PHE PHE A . n A 1 87 ASP 87 87 87 ASP ASP A . n A 1 88 GLY 88 88 88 GLY GLY A . n A 1 89 LYS 89 89 89 LYS LYS A . n A 1 90 TYR 90 90 90 TYR TYR A . n A 1 91 ALA 91 91 91 ALA ALA A . n A 1 92 PHE 92 92 92 PHE PHE A . n A 1 93 LEU 93 93 93 LEU LEU A . n A 1 94 LYS 94 94 94 LYS LYS A . n A 1 95 THR 95 95 95 THR THR A . n A 1 96 TYR 96 96 96 TYR TYR A . n A 1 97 ASN 97 97 97 ASN ASN A . n A 1 98 TYR 98 98 98 TYR TYR A . n A 1 99 SER 99 99 99 SER SER A . n A 1 100 LEU 100 100 100 LEU LEU A . n A 1 101 GLY 101 101 101 GLY GLY A . n A 1 102 ALA 102 102 102 ALA ALA A . n A 1 103 ASP 103 103 103 ASP ASP A . n A 1 104 ASP 104 104 104 ASP ASP A . n A 1 105 LEU 105 105 105 LEU LEU A . n A 1 106 THR 106 106 106 THR THR A . n A 1 107 PRO 107 107 107 PRO PRO A . n A 1 108 PHE 108 108 108 PHE PHE A . n A 1 109 GLY 109 109 109 GLY GLY A . n A 1 110 GLU 110 110 110 GLU GLU A . n A 1 111 GLN 111 111 111 GLN GLN A . n A 1 112 GLU 112 112 112 GLU GLU A . n A 1 113 LEU 113 113 113 LEU LEU A . n A 1 114 VAL 114 114 114 VAL VAL A . n A 1 115 ASN 115 115 115 ASN ASN A . n A 1 116 SER 116 116 116 SER SER A . n A 1 117 GLY 117 117 117 GLY GLY A . n A 1 118 ILE 118 118 118 ILE ILE A . n A 1 119 LYS 119 119 119 LYS LYS A . n A 1 120 PHE 120 120 120 PHE PHE A . n A 1 121 TYR 121 121 121 TYR TYR A . n A 1 122 GLN 122 122 122 GLN GLN A . n A 1 123 ARG 123 123 123 ARG ARG A . n A 1 124 TYR 124 124 124 TYR TYR A . n A 1 125 GLU 125 125 125 GLU GLU A . n A 1 126 SER 126 126 126 SER SER A . n A 1 127 LEU 127 127 127 LEU LEU A . n A 1 128 THR 128 128 128 THR THR A . n A 1 129 ARG 129 129 129 ARG ARG A . n A 1 130 ASN 130 130 130 ASN ASN A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 VAL 132 132 132 VAL VAL A . n A 1 133 PRO 133 133 133 PRO PRO A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ILE 135 135 135 ILE ILE A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 SER 137 137 137 SER SER A . n A 1 138 SER 138 138 138 SER SER A . n A 1 139 GLY 139 139 139 GLY GLY A . n A 1 140 SER 140 140 140 SER SER A . n A 1 141 SER 141 141 141 SER SER A . n A 1 142 ARG 142 142 142 ARG ARG A . n A 1 143 VAL 143 143 143 VAL VAL A . n A 1 144 ILE 144 144 144 ILE ILE A . n A 1 145 ALA 145 145 145 ALA ALA A . n A 1 146 SER 146 146 146 SER SER A . n A 1 147 GLY 147 147 147 GLY GLY A . n A 1 148 LYS 148 148 148 LYS LYS A . n A 1 149 LYS 149 149 149 LYS LYS A . n A 1 150 PHE 150 150 150 PHE PHE A . n A 1 151 ILE 151 151 151 ILE ILE A . n A 1 152 GLU 152 152 152 GLU GLU A . n A 1 153 GLY 153 153 153 GLY GLY A . n A 1 154 PHE 154 154 154 PHE PHE A . n A 1 155 GLN 155 155 155 GLN GLN A . n A 1 156 SER 156 156 156 SER SER A . n A 1 157 THR 157 157 157 THR THR A . n A 1 158 LYS 158 158 158 LYS LYS A . n A 1 159 LEU 159 159 159 LEU LEU A . n A 1 160 LYS 160 160 160 LYS LYS A . n A 1 161 ASP 161 161 161 ASP ASP A . n A 1 162 PRO 162 162 162 PRO PRO A . n A 1 163 ARG 163 163 163 ARG ARG A . n A 1 164 ALA 164 164 164 ALA ALA A . n A 1 165 GLN 165 165 165 GLN GLN A . n A 1 166 PRO 166 166 166 PRO PRO A . n A 1 167 GLY 167 167 167 GLY GLY A . n A 1 168 GLN 168 168 168 GLN GLN A . n A 1 169 SER 169 169 169 SER SER A . n A 1 170 SER 170 170 170 SER SER A . n A 1 171 PRO 171 171 171 PRO PRO A . n A 1 172 LYS 172 172 172 LYS LYS A . n A 1 173 ILE 173 173 173 ILE ILE A . n A 1 174 ASP 174 174 174 ASP ASP A . n A 1 175 VAL 175 175 175 VAL VAL A . n A 1 176 VAL 176 176 176 VAL VAL A . n A 1 177 ILE 177 177 177 ILE ILE A . n A 1 178 SER 178 178 178 SER SER A . n A 1 179 GLU 179 179 179 GLU GLU A . n A 1 180 ALA 180 180 180 ALA ALA A . n A 1 181 SER 181 181 181 SER SER A . n A 1 182 SER 182 182 182 SER SER A . n A 1 183 SER 183 183 183 SER SER A . n A 1 184 ASN 184 184 184 ASN ASN A . n A 1 185 ASN 185 185 185 ASN ASN A . n A 1 186 THR 186 186 186 THR THR A . n A 1 187 LEU 187 187 187 LEU LEU A . n A 1 188 ASP 188 188 188 ASP ASP A . n A 1 189 PRO 189 189 189 PRO PRO A . n A 1 190 GLY 190 190 190 GLY GLY A . n A 1 191 THR 191 191 191 THR THR A . n A 1 192 CYS 192 192 192 CYS CYS A . n A 1 193 THR 193 193 193 THR THR A . n A 1 194 VAL 194 194 194 VAL VAL A . n A 1 195 PHE 195 195 195 PHE PHE A . n A 1 196 GLU 196 196 196 GLU GLU A . n A 1 197 ASP 197 197 197 ASP ASP A . n A 1 198 SER 198 198 198 SER SER A . n A 1 199 GLU 199 199 199 GLU GLU A . n A 1 200 LEU 200 200 200 LEU LEU A . n A 1 201 ALA 201 201 201 ALA ALA A . n A 1 202 ASP 202 202 202 ASP ASP A . n A 1 203 THR 203 203 203 THR THR A . n A 1 204 VAL 204 204 204 VAL VAL A . n A 1 205 GLU 205 205 205 GLU GLU A . n A 1 206 ALA 206 206 206 ALA ALA A . n A 1 207 ASN 207 207 207 ASN ASN A . n A 1 208 PHE 208 208 208 PHE PHE A . n A 1 209 THR 209 209 209 THR THR A . n A 1 210 ALA 210 210 210 ALA ALA A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 PHE 212 212 212 PHE PHE A . n A 1 213 VAL 213 213 213 VAL VAL A . n A 1 214 PRO 214 214 214 PRO PRO A . n A 1 215 SER 215 215 215 SER SER A . n A 1 216 ILE 216 216 216 ILE ILE A . n A 1 217 ARG 217 217 217 ARG ARG A . n A 1 218 GLN 218 218 218 GLN GLN A . n A 1 219 ARG 219 219 219 ARG ARG A . n A 1 220 LEU 220 220 220 LEU LEU A . n A 1 221 GLU 221 221 221 GLU GLU A . n A 1 222 ASN 222 222 222 ASN ASN A . n A 1 223 ASP 223 223 223 ASP ASP A . n A 1 224 LEU 224 224 224 LEU LEU A . n A 1 225 SER 225 225 225 SER SER A . n A 1 226 GLY 226 226 226 GLY GLY A . n A 1 227 VAL 227 227 227 VAL VAL A . n A 1 228 THR 228 228 228 THR THR A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 THR 230 230 230 THR THR A . n A 1 231 ASP 231 231 231 ASP ASP A . n A 1 232 THR 232 232 232 THR THR A . n A 1 233 GLU 233 233 233 GLU GLU A . n A 1 234 VAL 234 234 234 VAL VAL A . n A 1 235 THR 235 235 235 THR THR A . n A 1 236 TYR 236 236 236 TYR TYR A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 MET 238 238 238 MET MET A . n A 1 239 ASP 239 239 239 ASP ASP A . n A 1 240 MET 240 240 240 MET MET A . n A 1 241 CYS 241 241 241 CYS CYS A . n A 1 242 SER 242 242 242 SER SER A . n A 1 243 PHE 243 243 243 PHE PHE A . n A 1 244 ASP 244 244 244 ASP ASP A . n A 1 245 THR 245 245 245 THR THR A . n A 1 246 ILE 246 246 246 ILE ILE A . n A 1 247 SER 247 247 247 SER SER A . n A 1 248 THR 248 248 248 THR THR A . n A 1 249 SER 249 249 249 SER SER A . n A 1 250 THR 250 250 250 THR THR A . n A 1 251 VAL 251 251 251 VAL VAL A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 THR 253 253 253 THR THR A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 LEU 255 255 255 LEU LEU A . n A 1 256 SER 256 256 256 SER SER A . n A 1 257 PRO 257 257 257 PRO PRO A . n A 1 258 PHE 258 258 258 PHE PHE A . n A 1 259 CYS 259 259 259 CYS CYS A . n A 1 260 ASP 260 260 260 ASP ASP A . n A 1 261 LEU 261 261 261 LEU LEU A . n A 1 262 PHE 262 262 262 PHE PHE A . n A 1 263 THR 263 263 263 THR THR A . n A 1 264 HIS 264 264 264 HIS HIS A . n A 1 265 ASP 265 265 265 ASP ASP A . n A 1 266 GLU 266 266 266 GLU GLU A . n A 1 267 TRP 267 267 267 TRP TRP A . n A 1 268 ILE 268 268 268 ILE ILE A . n A 1 269 ASN 269 269 269 ASN ASN A . n A 1 270 TYR 270 270 270 TYR TYR A . n A 1 271 ASP 271 271 271 ASP ASP A . n A 1 272 TYR 272 272 272 TYR TYR A . n A 1 273 LEU 273 273 273 LEU LEU A . n A 1 274 GLN 274 274 274 GLN GLN A . n A 1 275 SER 275 275 275 SER SER A . n A 1 276 LEU 276 276 276 LEU LEU A . n A 1 277 LYS 277 277 277 LYS LYS A . n A 1 278 LYS 278 278 278 LYS LYS A . n A 1 279 TYR 279 279 279 TYR TYR A . n A 1 280 TYR 280 280 280 TYR TYR A . n A 1 281 GLY 281 281 281 GLY GLY A . n A 1 282 HIS 282 282 282 HIS HIS A . n A 1 283 GLY 283 283 283 GLY GLY A . n A 1 284 ALA 284 284 284 ALA ALA A . n A 1 285 GLY 285 285 285 GLY GLY A . n A 1 286 ASN 286 286 286 ASN ASN A . n A 1 287 PRO 287 287 287 PRO PRO A . n A 1 288 LEU 288 288 288 LEU LEU A . n A 1 289 GLY 289 289 289 GLY GLY A . n A 1 290 PRO 290 290 290 PRO PRO A . n A 1 291 THR 291 291 291 THR THR A . n A 1 292 GLN 292 292 292 GLN GLN A . n A 1 293 GLY 293 293 293 GLY GLY A . n A 1 294 VAL 294 294 294 VAL VAL A . n A 1 295 GLY 295 295 295 GLY GLY A . n A 1 296 TYR 296 296 296 TYR TYR A . n A 1 297 ALA 297 297 297 ALA ALA A . n A 1 298 ASN 298 298 298 ASN ASN A . n A 1 299 GLU 299 299 299 GLU GLU A . n A 1 300 LEU 300 300 300 LEU LEU A . n A 1 301 ILE 301 301 301 ILE ILE A . n A 1 302 ALA 302 302 302 ALA ALA A . n A 1 303 ARG 303 303 303 ARG ARG A . n A 1 304 LEU 304 304 304 LEU LEU A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 HIS 306 306 306 HIS HIS A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 PRO 308 308 308 PRO PRO A . n A 1 309 VAL 309 309 309 VAL VAL A . n A 1 310 HIS 310 310 310 HIS HIS A . n A 1 311 ASP 311 311 311 ASP ASP A . n A 1 312 ASP 312 312 312 ASP ASP A . n A 1 313 THR 313 313 313 THR THR A . n A 1 314 SER 314 314 314 SER SER A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASN 316 316 316 ASN ASN A . n A 1 317 HIS 317 317 317 HIS HIS A . n A 1 318 THR 318 318 318 THR THR A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 SER 321 321 321 SER SER A . n A 1 322 SER 322 322 322 SER SER A . n A 1 323 PRO 323 323 323 PRO PRO A . n A 1 324 ALA 324 324 324 ALA ALA A . n A 1 325 THR 325 325 325 THR THR A . n A 1 326 PHE 326 326 326 PHE PHE A . n A 1 327 PRO 327 327 327 PRO PRO A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 ASN 329 329 329 ASN ASN A . n A 1 330 SER 330 330 330 SER SER A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 LEU 332 332 332 LEU LEU A . n A 1 333 TYR 333 333 333 TYR TYR A . n A 1 334 ALA 334 334 334 ALA ALA A . n A 1 335 ASP 335 335 335 ASP ASP A . n A 1 336 PHE 336 336 336 PHE PHE A . n A 1 337 SER 337 337 337 SER SER A . n A 1 338 HIS 338 338 338 HIS HIS A . n A 1 339 ASP 339 339 339 ASP ASP A . n A 1 340 ASN 340 340 340 ASN ASN A . n A 1 341 GLY 341 341 341 GLY GLY A . n A 1 342 ILE 342 342 342 ILE ILE A . n A 1 343 ILE 343 343 343 ILE ILE A . n A 1 344 SER 344 344 344 SER SER A . n A 1 345 ILE 345 345 345 ILE ILE A . n A 1 346 LEU 346 346 346 LEU LEU A . n A 1 347 PHE 347 347 347 PHE PHE A . n A 1 348 ALA 348 348 348 ALA ALA A . n A 1 349 LEU 349 349 349 LEU LEU A . n A 1 350 GLY 350 350 350 GLY GLY A . n A 1 351 LEU 351 351 351 LEU LEU A . n A 1 352 TYR 352 352 352 TYR TYR A . n A 1 353 ASN 353 353 353 ASN ASN A . n A 1 354 GLY 354 354 354 GLY GLY A . n A 1 355 THR 355 355 355 THR THR A . n A 1 356 LYS 356 356 356 LYS LYS A . n A 1 357 PRO 357 357 357 PRO PRO A . n A 1 358 LEU 358 358 358 LEU LEU A . n A 1 359 SER 359 359 359 SER SER A . n A 1 360 THR 360 360 360 THR THR A . n A 1 361 THR 361 361 361 THR THR A . n A 1 362 THR 362 362 362 THR THR A . n A 1 363 VAL 363 363 363 VAL VAL A . n A 1 364 GLU 364 364 364 GLU GLU A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 ILE 366 366 366 ILE ILE A . n A 1 367 THR 367 367 367 THR THR A . n A 1 368 GLN 368 368 368 GLN GLN A . n A 1 369 THR 369 369 369 THR THR A . n A 1 370 ASP 370 370 370 ASP ASP A . n A 1 371 GLY 371 371 371 GLY GLY A . n A 1 372 PHE 372 372 372 PHE PHE A . n A 1 373 SER 373 373 373 SER SER A . n A 1 374 SER 374 374 374 SER SER A . n A 1 375 ALA 375 375 375 ALA ALA A . n A 1 376 TRP 376 376 376 TRP TRP A . n A 1 377 THR 377 377 377 THR THR A . n A 1 378 VAL 378 378 378 VAL VAL A . n A 1 379 PRO 379 379 379 PRO PRO A . n A 1 380 PHE 380 380 380 PHE PHE A . n A 1 381 ALA 381 381 381 ALA ALA A . n A 1 382 SER 382 382 382 SER SER A . n A 1 383 ARG 383 383 383 ARG ARG A . n A 1 384 LEU 384 384 384 LEU LEU A . n A 1 385 TYR 385 385 385 TYR TYR A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 GLU 387 387 387 GLU GLU A . n A 1 388 MET 388 388 388 MET MET A . n A 1 389 MET 389 389 389 MET MET A . n A 1 390 GLN 390 390 390 GLN GLN A . n A 1 391 CYS 391 391 391 CYS CYS A . n A 1 392 GLN 392 392 392 GLN GLN A . n A 1 393 ALA 393 393 393 ALA ALA A . n A 1 394 GLU 394 394 394 GLU GLU A . n A 1 395 GLN 395 395 395 GLN GLN A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PRO 397 397 397 PRO PRO A . n A 1 398 LEU 398 398 398 LEU LEU A . n A 1 399 VAL 399 399 399 VAL VAL A . n A 1 400 ARG 400 400 400 ARG ARG A . n A 1 401 VAL 401 401 401 VAL VAL A . n A 1 402 LEU 402 402 402 LEU LEU A . n A 1 403 VAL 403 403 403 VAL VAL A . n A 1 404 ASN 404 404 404 ASN ASN A . n A 1 405 ASP 405 405 405 ASP ASP A . n A 1 406 ARG 406 406 406 ARG ARG A . n A 1 407 VAL 407 407 407 VAL VAL A . n A 1 408 VAL 408 408 408 VAL VAL A . n A 1 409 PRO 409 409 409 PRO PRO A . n A 1 410 LEU 410 410 410 LEU LEU A . n A 1 411 HIS 411 411 411 HIS HIS A . n A 1 412 GLY 412 412 412 GLY GLY A . n A 1 413 CYS 413 413 413 CYS CYS A . n A 1 414 PRO 414 414 414 PRO PRO A . n A 1 415 VAL 415 415 415 VAL VAL A . n A 1 416 ASP 416 416 416 ASP ASP A . n A 1 417 ALA 417 417 417 ALA ALA A . n A 1 418 LEU 418 418 418 LEU LEU A . n A 1 419 GLY 419 419 419 GLY GLY A . n A 1 420 ARG 420 420 420 ARG ARG A . n A 1 421 CYS 421 421 421 CYS CYS A . n A 1 422 THR 422 422 422 THR THR A . n A 1 423 ARG 423 423 423 ARG ARG A . n A 1 424 ASP 424 424 424 ASP ASP A . n A 1 425 SER 425 425 425 SER SER A . n A 1 426 PHE 426 426 426 PHE PHE A . n A 1 427 VAL 427 427 427 VAL VAL A . n A 1 428 ARG 428 428 428 ARG ARG A . n A 1 429 GLY 429 429 429 GLY GLY A . n A 1 430 LEU 430 430 430 LEU LEU A . n A 1 431 SER 431 431 431 SER SER A . n A 1 432 PHE 432 432 432 PHE PHE A . n A 1 433 ALA 433 433 433 ALA ALA A . n A 1 434 ARG 434 434 434 ARG ARG A . n A 1 435 SER 435 435 435 SER SER A . n A 1 436 GLY 436 436 436 GLY GLY A . n A 1 437 GLY 437 437 437 GLY GLY A . n A 1 438 ASP 438 438 438 ASP ASP A . n A 1 439 TRP 439 439 439 TRP TRP A . n A 1 440 ALA 440 440 440 ALA ALA A . n A 1 441 GLU 441 441 441 GLU GLU A . n A 1 442 CYS 442 442 442 CYS CYS A . n A 1 443 PHE 443 443 443 PHE PHE A . n A 1 444 ALA 444 444 444 ALA ALA A . n B 1 1 ALA 1 1 ? ? ? B . n B 1 2 SER 2 2 ? ? ? B . n B 1 3 ARG 3 3 ? ? ? B . n B 1 4 ASN 4 4 ? ? ? B . n B 1 5 GLN 5 5 ? ? ? B . n B 1 6 SER 6 6 ? ? ? B . n B 1 7 SER 7 7 7 SER SER B . n B 1 8 CYS 8 8 8 CYS CYS B . n B 1 9 ASP 9 9 9 ASP ASP B . n B 1 10 THR 10 10 10 THR THR B . n B 1 11 VAL 11 11 11 VAL VAL B . n B 1 12 ASP 12 12 12 ASP ASP B . n B 1 13 GLN 13 13 13 GLN GLN B . n B 1 14 GLY 14 14 14 GLY GLY B . n B 1 15 TYR 15 15 15 TYR TYR B . n B 1 16 GLN 16 16 16 GLN GLN B . n B 1 17 CYS 17 17 17 CYS CYS B . n B 1 18 PHE 18 18 18 PHE PHE B . n B 1 19 SER 19 19 19 SER SER B . n B 1 20 GLU 20 20 20 GLU GLU B . n B 1 21 THR 21 21 21 THR THR B . n B 1 22 SER 22 22 22 SER SER B . n B 1 23 HIS 23 23 23 HIS HIS B . n B 1 24 LEU 24 24 24 LEU LEU B . n B 1 25 TRP 25 25 25 TRP TRP B . n B 1 26 GLY 26 26 26 GLY GLY B . n B 1 27 GLN 27 27 27 GLN GLN B . n B 1 28 TYR 28 28 28 TYR TYR B . n B 1 29 ALA 29 29 29 ALA ALA B . n B 1 30 PRO 30 30 30 PRO PRO B . n B 1 31 PHE 31 31 31 PHE PHE B . n B 1 32 PHE 32 32 32 PHE PHE B . n B 1 33 SER 33 33 33 SER SER B . n B 1 34 LEU 34 34 34 LEU LEU B . n B 1 35 ALA 35 35 35 ALA ALA B . n B 1 36 ASN 36 36 36 ASN ASN B . n B 1 37 GLU 37 37 37 GLU GLU B . n B 1 38 SER 38 38 38 SER SER B . n B 1 39 VAL 39 39 39 VAL VAL B . n B 1 40 ILE 40 40 40 ILE ILE B . n B 1 41 SER 41 41 41 SER SER B . n B 1 42 PRO 42 42 42 PRO PRO B . n B 1 43 GLU 43 43 43 GLU GLU B . n B 1 44 VAL 44 44 44 VAL VAL B . n B 1 45 PRO 45 45 45 PRO PRO B . n B 1 46 ALA 46 46 46 ALA ALA B . n B 1 47 GLY 47 47 47 GLY GLY B . n B 1 48 CYS 48 48 48 CYS CYS B . n B 1 49 ARG 49 49 49 ARG ARG B . n B 1 50 VAL 50 50 50 VAL VAL B . n B 1 51 THR 51 51 51 THR THR B . n B 1 52 PHE 52 52 52 PHE PHE B . n B 1 53 ALA 53 53 53 ALA ALA B . n B 1 54 GLN 54 54 54 GLN GLN B . n B 1 55 VAL 55 55 55 VAL VAL B . n B 1 56 LEU 56 56 56 LEU LEU B . n B 1 57 SER 57 57 57 SER SER B . n B 1 58 ARG 58 58 58 ARG ARG B . n B 1 59 HIS 59 59 59 HIS HIS B . n B 1 60 GLY 60 60 60 GLY GLY B . n B 1 61 ALA 61 61 61 ALA ALA B . n B 1 62 ARG 62 62 62 ARG ARG B . n B 1 63 TYR 63 63 63 TYR TYR B . n B 1 64 PRO 64 64 64 PRO PRO B . n B 1 65 THR 65 65 65 THR THR B . n B 1 66 ASP 66 66 66 ASP ASP B . n B 1 67 SER 67 67 67 SER SER B . n B 1 68 LYS 68 68 68 LYS LYS B . n B 1 69 GLY 69 69 69 GLY GLY B . n B 1 70 LYS 70 70 70 LYS LYS B . n B 1 71 LYS 71 71 71 LYS LYS B . n B 1 72 TYR 72 72 72 TYR TYR B . n B 1 73 SER 73 73 73 SER SER B . n B 1 74 ALA 74 74 74 ALA ALA B . n B 1 75 LEU 75 75 75 LEU LEU B . n B 1 76 ILE 76 76 76 ILE ILE B . n B 1 77 GLU 77 77 77 GLU GLU B . n B 1 78 GLU 78 78 78 GLU GLU B . n B 1 79 ILE 79 79 79 ILE ILE B . n B 1 80 GLN 80 80 80 GLN GLN B . n B 1 81 GLN 81 81 81 GLN GLN B . n B 1 82 ASN 82 82 82 ASN ASN B . n B 1 83 ALA 83 83 83 ALA ALA B . n B 1 84 THR 84 84 84 THR THR B . n B 1 85 THR 85 85 85 THR THR B . n B 1 86 PHE 86 86 86 PHE PHE B . n B 1 87 ASP 87 87 87 ASP ASP B . n B 1 88 GLY 88 88 88 GLY GLY B . n B 1 89 LYS 89 89 89 LYS LYS B . n B 1 90 TYR 90 90 90 TYR TYR B . n B 1 91 ALA 91 91 91 ALA ALA B . n B 1 92 PHE 92 92 92 PHE PHE B . n B 1 93 LEU 93 93 93 LEU LEU B . n B 1 94 LYS 94 94 94 LYS LYS B . n B 1 95 THR 95 95 95 THR THR B . n B 1 96 TYR 96 96 96 TYR TYR B . n B 1 97 ASN 97 97 97 ASN ASN B . n B 1 98 TYR 98 98 98 TYR TYR B . n B 1 99 SER 99 99 99 SER SER B . n B 1 100 LEU 100 100 100 LEU LEU B . n B 1 101 GLY 101 101 101 GLY GLY B . n B 1 102 ALA 102 102 102 ALA ALA B . n B 1 103 ASP 103 103 103 ASP ASP B . n B 1 104 ASP 104 104 104 ASP ASP B . n B 1 105 LEU 105 105 105 LEU LEU B . n B 1 106 THR 106 106 106 THR THR B . n B 1 107 PRO 107 107 107 PRO PRO B . n B 1 108 PHE 108 108 108 PHE PHE B . n B 1 109 GLY 109 109 109 GLY GLY B . n B 1 110 GLU 110 110 110 GLU GLU B . n B 1 111 GLN 111 111 111 GLN GLN B . n B 1 112 GLU 112 112 112 GLU GLU B . n B 1 113 LEU 113 113 113 LEU LEU B . n B 1 114 VAL 114 114 114 VAL VAL B . n B 1 115 ASN 115 115 115 ASN ASN B . n B 1 116 SER 116 116 116 SER SER B . n B 1 117 GLY 117 117 117 GLY GLY B . n B 1 118 ILE 118 118 118 ILE ILE B . n B 1 119 LYS 119 119 119 LYS LYS B . n B 1 120 PHE 120 120 120 PHE PHE B . n B 1 121 TYR 121 121 121 TYR TYR B . n B 1 122 GLN 122 122 122 GLN GLN B . n B 1 123 ARG 123 123 123 ARG ARG B . n B 1 124 TYR 124 124 124 TYR TYR B . n B 1 125 GLU 125 125 125 GLU GLU B . n B 1 126 SER 126 126 126 SER SER B . n B 1 127 LEU 127 127 127 LEU LEU B . n B 1 128 THR 128 128 128 THR THR B . n B 1 129 ARG 129 129 129 ARG ARG B . n B 1 130 ASN 130 130 130 ASN ASN B . n B 1 131 ILE 131 131 131 ILE ILE B . n B 1 132 VAL 132 132 132 VAL VAL B . n B 1 133 PRO 133 133 133 PRO PRO B . n B 1 134 PHE 134 134 134 PHE PHE B . n B 1 135 ILE 135 135 135 ILE ILE B . n B 1 136 ARG 136 136 136 ARG ARG B . n B 1 137 SER 137 137 137 SER SER B . n B 1 138 SER 138 138 138 SER SER B . n B 1 139 GLY 139 139 139 GLY GLY B . n B 1 140 SER 140 140 140 SER SER B . n B 1 141 SER 141 141 141 SER SER B . n B 1 142 ARG 142 142 142 ARG ARG B . n B 1 143 VAL 143 143 143 VAL VAL B . n B 1 144 ILE 144 144 144 ILE ILE B . n B 1 145 ALA 145 145 145 ALA ALA B . n B 1 146 SER 146 146 146 SER SER B . n B 1 147 GLY 147 147 147 GLY GLY B . n B 1 148 LYS 148 148 148 LYS LYS B . n B 1 149 LYS 149 149 149 LYS LYS B . n B 1 150 PHE 150 150 150 PHE PHE B . n B 1 151 ILE 151 151 151 ILE ILE B . n B 1 152 GLU 152 152 152 GLU GLU B . n B 1 153 GLY 153 153 153 GLY GLY B . n B 1 154 PHE 154 154 154 PHE PHE B . n B 1 155 GLN 155 155 155 GLN GLN B . n B 1 156 SER 156 156 156 SER SER B . n B 1 157 THR 157 157 157 THR THR B . n B 1 158 LYS 158 158 158 LYS LYS B . n B 1 159 LEU 159 159 159 LEU LEU B . n B 1 160 LYS 160 160 160 LYS LYS B . n B 1 161 ASP 161 161 161 ASP ASP B . n B 1 162 PRO 162 162 162 PRO PRO B . n B 1 163 ARG 163 163 163 ARG ARG B . n B 1 164 ALA 164 164 164 ALA ALA B . n B 1 165 GLN 165 165 165 GLN GLN B . n B 1 166 PRO 166 166 166 PRO PRO B . n B 1 167 GLY 167 167 167 GLY GLY B . n B 1 168 GLN 168 168 168 GLN GLN B . n B 1 169 SER 169 169 169 SER SER B . n B 1 170 SER 170 170 170 SER SER B . n B 1 171 PRO 171 171 171 PRO PRO B . n B 1 172 LYS 172 172 172 LYS LYS B . n B 1 173 ILE 173 173 173 ILE ILE B . n B 1 174 ASP 174 174 174 ASP ASP B . n B 1 175 VAL 175 175 175 VAL VAL B . n B 1 176 VAL 176 176 176 VAL VAL B . n B 1 177 ILE 177 177 177 ILE ILE B . n B 1 178 SER 178 178 178 SER SER B . n B 1 179 GLU 179 179 179 GLU GLU B . n B 1 180 ALA 180 180 180 ALA ALA B . n B 1 181 SER 181 181 181 SER SER B . n B 1 182 SER 182 182 182 SER SER B . n B 1 183 SER 183 183 183 SER SER B . n B 1 184 ASN 184 184 184 ASN ASN B . n B 1 185 ASN 185 185 185 ASN ASN B . n B 1 186 THR 186 186 186 THR THR B . n B 1 187 LEU 187 187 187 LEU LEU B . n B 1 188 ASP 188 188 188 ASP ASP B . n B 1 189 PRO 189 189 189 PRO PRO B . n B 1 190 GLY 190 190 190 GLY GLY B . n B 1 191 THR 191 191 191 THR THR B . n B 1 192 CYS 192 192 192 CYS CYS B . n B 1 193 THR 193 193 193 THR THR B . n B 1 194 VAL 194 194 194 VAL VAL B . n B 1 195 PHE 195 195 195 PHE PHE B . n B 1 196 GLU 196 196 196 GLU GLU B . n B 1 197 ASP 197 197 197 ASP ASP B . n B 1 198 SER 198 198 198 SER SER B . n B 1 199 GLU 199 199 199 GLU GLU B . n B 1 200 LEU 200 200 200 LEU LEU B . n B 1 201 ALA 201 201 201 ALA ALA B . n B 1 202 ASP 202 202 202 ASP ASP B . n B 1 203 THR 203 203 203 THR THR B . n B 1 204 VAL 204 204 204 VAL VAL B . n B 1 205 GLU 205 205 205 GLU GLU B . n B 1 206 ALA 206 206 206 ALA ALA B . n B 1 207 ASN 207 207 207 ASN ASN B . n B 1 208 PHE 208 208 208 PHE PHE B . n B 1 209 THR 209 209 209 THR THR B . n B 1 210 ALA 210 210 210 ALA ALA B . n B 1 211 THR 211 211 211 THR THR B . n B 1 212 PHE 212 212 212 PHE PHE B . n B 1 213 VAL 213 213 213 VAL VAL B . n B 1 214 PRO 214 214 214 PRO PRO B . n B 1 215 SER 215 215 215 SER SER B . n B 1 216 ILE 216 216 216 ILE ILE B . n B 1 217 ARG 217 217 217 ARG ARG B . n B 1 218 GLN 218 218 218 GLN GLN B . n B 1 219 ARG 219 219 219 ARG ARG B . n B 1 220 LEU 220 220 220 LEU LEU B . n B 1 221 GLU 221 221 221 GLU GLU B . n B 1 222 ASN 222 222 222 ASN ASN B . n B 1 223 ASP 223 223 223 ASP ASP B . n B 1 224 LEU 224 224 224 LEU LEU B . n B 1 225 SER 225 225 225 SER SER B . n B 1 226 GLY 226 226 226 GLY GLY B . n B 1 227 VAL 227 227 227 VAL VAL B . n B 1 228 THR 228 228 228 THR THR B . n B 1 229 LEU 229 229 229 LEU LEU B . n B 1 230 THR 230 230 230 THR THR B . n B 1 231 ASP 231 231 231 ASP ASP B . n B 1 232 THR 232 232 232 THR THR B . n B 1 233 GLU 233 233 233 GLU GLU B . n B 1 234 VAL 234 234 234 VAL VAL B . n B 1 235 THR 235 235 235 THR THR B . n B 1 236 TYR 236 236 236 TYR TYR B . n B 1 237 LEU 237 237 237 LEU LEU B . n B 1 238 MET 238 238 238 MET MET B . n B 1 239 ASP 239 239 239 ASP ASP B . n B 1 240 MET 240 240 240 MET MET B . n B 1 241 CYS 241 241 241 CYS CYS B . n B 1 242 SER 242 242 242 SER SER B . n B 1 243 PHE 243 243 243 PHE PHE B . n B 1 244 ASP 244 244 244 ASP ASP B . n B 1 245 THR 245 245 245 THR THR B . n B 1 246 ILE 246 246 246 ILE ILE B . n B 1 247 SER 247 247 247 SER SER B . n B 1 248 THR 248 248 248 THR THR B . n B 1 249 SER 249 249 249 SER SER B . n B 1 250 THR 250 250 250 THR THR B . n B 1 251 VAL 251 251 251 VAL VAL B . n B 1 252 ASP 252 252 252 ASP ASP B . n B 1 253 THR 253 253 253 THR THR B . n B 1 254 LYS 254 254 254 LYS LYS B . n B 1 255 LEU 255 255 255 LEU LEU B . n B 1 256 SER 256 256 256 SER SER B . n B 1 257 PRO 257 257 257 PRO PRO B . n B 1 258 PHE 258 258 258 PHE PHE B . n B 1 259 CYS 259 259 259 CYS CYS B . n B 1 260 ASP 260 260 260 ASP ASP B . n B 1 261 LEU 261 261 261 LEU LEU B . n B 1 262 PHE 262 262 262 PHE PHE B . n B 1 263 THR 263 263 263 THR THR B . n B 1 264 HIS 264 264 264 HIS HIS B . n B 1 265 ASP 265 265 265 ASP ASP B . n B 1 266 GLU 266 266 266 GLU GLU B . n B 1 267 TRP 267 267 267 TRP TRP B . n B 1 268 ILE 268 268 268 ILE ILE B . n B 1 269 ASN 269 269 269 ASN ASN B . n B 1 270 TYR 270 270 270 TYR TYR B . n B 1 271 ASP 271 271 271 ASP ASP B . n B 1 272 TYR 272 272 272 TYR TYR B . n B 1 273 LEU 273 273 273 LEU LEU B . n B 1 274 GLN 274 274 274 GLN GLN B . n B 1 275 SER 275 275 275 SER SER B . n B 1 276 LEU 276 276 276 LEU LEU B . n B 1 277 LYS 277 277 277 LYS LYS B . n B 1 278 LYS 278 278 278 LYS LYS B . n B 1 279 TYR 279 279 279 TYR TYR B . n B 1 280 TYR 280 280 280 TYR TYR B . n B 1 281 GLY 281 281 281 GLY GLY B . n B 1 282 HIS 282 282 282 HIS HIS B . n B 1 283 GLY 283 283 283 GLY GLY B . n B 1 284 ALA 284 284 284 ALA ALA B . n B 1 285 GLY 285 285 285 GLY GLY B . n B 1 286 ASN 286 286 286 ASN ASN B . n B 1 287 PRO 287 287 287 PRO PRO B . n B 1 288 LEU 288 288 288 LEU LEU B . n B 1 289 GLY 289 289 289 GLY GLY B . n B 1 290 PRO 290 290 290 PRO PRO B . n B 1 291 THR 291 291 291 THR THR B . n B 1 292 GLN 292 292 292 GLN GLN B . n B 1 293 GLY 293 293 293 GLY GLY B . n B 1 294 VAL 294 294 294 VAL VAL B . n B 1 295 GLY 295 295 295 GLY GLY B . n B 1 296 TYR 296 296 296 TYR TYR B . n B 1 297 ALA 297 297 297 ALA ALA B . n B 1 298 ASN 298 298 298 ASN ASN B . n B 1 299 GLU 299 299 299 GLU GLU B . n B 1 300 LEU 300 300 300 LEU LEU B . n B 1 301 ILE 301 301 301 ILE ILE B . n B 1 302 ALA 302 302 302 ALA ALA B . n B 1 303 ARG 303 303 303 ARG ARG B . n B 1 304 LEU 304 304 304 LEU LEU B . n B 1 305 THR 305 305 305 THR THR B . n B 1 306 HIS 306 306 306 HIS HIS B . n B 1 307 SER 307 307 307 SER SER B . n B 1 308 PRO 308 308 308 PRO PRO B . n B 1 309 VAL 309 309 309 VAL VAL B . n B 1 310 HIS 310 310 310 HIS HIS B . n B 1 311 ASP 311 311 311 ASP ASP B . n B 1 312 ASP 312 312 312 ASP ASP B . n B 1 313 THR 313 313 313 THR THR B . n B 1 314 SER 314 314 314 SER SER B . n B 1 315 SER 315 315 315 SER SER B . n B 1 316 ASN 316 316 316 ASN ASN B . n B 1 317 HIS 317 317 317 HIS HIS B . n B 1 318 THR 318 318 318 THR THR B . n B 1 319 LEU 319 319 319 LEU LEU B . n B 1 320 ASP 320 320 320 ASP ASP B . n B 1 321 SER 321 321 321 SER SER B . n B 1 322 SER 322 322 322 SER SER B . n B 1 323 PRO 323 323 323 PRO PRO B . n B 1 324 ALA 324 324 324 ALA ALA B . n B 1 325 THR 325 325 325 THR THR B . n B 1 326 PHE 326 326 326 PHE PHE B . n B 1 327 PRO 327 327 327 PRO PRO B . n B 1 328 LEU 328 328 328 LEU LEU B . n B 1 329 ASN 329 329 329 ASN ASN B . n B 1 330 SER 330 330 330 SER SER B . n B 1 331 THR 331 331 331 THR THR B . n B 1 332 LEU 332 332 332 LEU LEU B . n B 1 333 TYR 333 333 333 TYR TYR B . n B 1 334 ALA 334 334 334 ALA ALA B . n B 1 335 ASP 335 335 335 ASP ASP B . n B 1 336 PHE 336 336 336 PHE PHE B . n B 1 337 SER 337 337 337 SER SER B . n B 1 338 HIS 338 338 338 HIS HIS B . n B 1 339 ASP 339 339 339 ASP ASP B . n B 1 340 ASN 340 340 340 ASN ASN B . n B 1 341 GLY 341 341 341 GLY GLY B . n B 1 342 ILE 342 342 342 ILE ILE B . n B 1 343 ILE 343 343 343 ILE ILE B . n B 1 344 SER 344 344 344 SER SER B . n B 1 345 ILE 345 345 345 ILE ILE B . n B 1 346 LEU 346 346 346 LEU LEU B . n B 1 347 PHE 347 347 347 PHE PHE B . n B 1 348 ALA 348 348 348 ALA ALA B . n B 1 349 LEU 349 349 349 LEU LEU B . n B 1 350 GLY 350 350 350 GLY GLY B . n B 1 351 LEU 351 351 351 LEU LEU B . n B 1 352 TYR 352 352 352 TYR TYR B . n B 1 353 ASN 353 353 353 ASN ASN B . n B 1 354 GLY 354 354 354 GLY GLY B . n B 1 355 THR 355 355 355 THR THR B . n B 1 356 LYS 356 356 356 LYS LYS B . n B 1 357 PRO 357 357 357 PRO PRO B . n B 1 358 LEU 358 358 358 LEU LEU B . n B 1 359 SER 359 359 359 SER SER B . n B 1 360 THR 360 360 360 THR THR B . n B 1 361 THR 361 361 361 THR THR B . n B 1 362 THR 362 362 362 THR THR B . n B 1 363 VAL 363 363 363 VAL VAL B . n B 1 364 GLU 364 364 364 GLU GLU B . n B 1 365 ASN 365 365 365 ASN ASN B . n B 1 366 ILE 366 366 366 ILE ILE B . n B 1 367 THR 367 367 367 THR THR B . n B 1 368 GLN 368 368 368 GLN GLN B . n B 1 369 THR 369 369 369 THR THR B . n B 1 370 ASP 370 370 370 ASP ASP B . n B 1 371 GLY 371 371 371 GLY GLY B . n B 1 372 PHE 372 372 372 PHE PHE B . n B 1 373 SER 373 373 373 SER SER B . n B 1 374 SER 374 374 374 SER SER B . n B 1 375 ALA 375 375 375 ALA ALA B . n B 1 376 TRP 376 376 376 TRP TRP B . n B 1 377 THR 377 377 377 THR THR B . n B 1 378 VAL 378 378 378 VAL VAL B . n B 1 379 PRO 379 379 379 PRO PRO B . n B 1 380 PHE 380 380 380 PHE PHE B . n B 1 381 ALA 381 381 381 ALA ALA B . n B 1 382 SER 382 382 382 SER SER B . n B 1 383 ARG 383 383 383 ARG ARG B . n B 1 384 LEU 384 384 384 LEU LEU B . n B 1 385 TYR 385 385 385 TYR TYR B . n B 1 386 VAL 386 386 386 VAL VAL B . n B 1 387 GLU 387 387 387 GLU GLU B . n B 1 388 MET 388 388 388 MET MET B . n B 1 389 MET 389 389 389 MET MET B . n B 1 390 GLN 390 390 390 GLN GLN B . n B 1 391 CYS 391 391 391 CYS CYS B . n B 1 392 GLN 392 392 392 GLN GLN B . n B 1 393 ALA 393 393 393 ALA ALA B . n B 1 394 GLU 394 394 394 GLU GLU B . n B 1 395 GLN 395 395 395 GLN GLN B . n B 1 396 GLU 396 396 396 GLU GLU B . n B 1 397 PRO 397 397 397 PRO PRO B . n B 1 398 LEU 398 398 398 LEU LEU B . n B 1 399 VAL 399 399 399 VAL VAL B . n B 1 400 ARG 400 400 400 ARG ARG B . n B 1 401 VAL 401 401 401 VAL VAL B . n B 1 402 LEU 402 402 402 LEU LEU B . n B 1 403 VAL 403 403 403 VAL VAL B . n B 1 404 ASN 404 404 404 ASN ASN B . n B 1 405 ASP 405 405 405 ASP ASP B . n B 1 406 ARG 406 406 406 ARG ARG B . n B 1 407 VAL 407 407 407 VAL VAL B . n B 1 408 VAL 408 408 408 VAL VAL B . n B 1 409 PRO 409 409 409 PRO PRO B . n B 1 410 LEU 410 410 410 LEU LEU B . n B 1 411 HIS 411 411 411 HIS HIS B . n B 1 412 GLY 412 412 412 GLY GLY B . n B 1 413 CYS 413 413 413 CYS CYS B . n B 1 414 PRO 414 414 414 PRO PRO B . n B 1 415 VAL 415 415 415 VAL VAL B . n B 1 416 ASP 416 416 416 ASP ASP B . n B 1 417 ALA 417 417 417 ALA ALA B . n B 1 418 LEU 418 418 418 LEU LEU B . n B 1 419 GLY 419 419 419 GLY GLY B . n B 1 420 ARG 420 420 420 ARG ARG B . n B 1 421 CYS 421 421 421 CYS CYS B . n B 1 422 THR 422 422 422 THR THR B . n B 1 423 ARG 423 423 423 ARG ARG B . n B 1 424 ASP 424 424 424 ASP ASP B . n B 1 425 SER 425 425 425 SER SER B . n B 1 426 PHE 426 426 426 PHE PHE B . n B 1 427 VAL 427 427 427 VAL VAL B . n B 1 428 ARG 428 428 428 ARG ARG B . n B 1 429 GLY 429 429 429 GLY GLY B . n B 1 430 LEU 430 430 430 LEU LEU B . n B 1 431 SER 431 431 431 SER SER B . n B 1 432 PHE 432 432 432 PHE PHE B . n B 1 433 ALA 433 433 433 ALA ALA B . n B 1 434 ARG 434 434 434 ARG ARG B . n B 1 435 SER 435 435 435 SER SER B . n B 1 436 GLY 436 436 436 GLY GLY B . n B 1 437 GLY 437 437 437 GLY GLY B . n B 1 438 ASP 438 438 438 ASP ASP B . n B 1 439 TRP 439 439 439 TRP TRP B . n B 1 440 ALA 440 440 440 ALA ALA B . n B 1 441 GLU 441 441 441 GLU GLU B . n B 1 442 CYS 442 442 442 CYS CYS B . n B 1 443 PHE 443 443 443 PHE PHE B . n B 1 444 ALA 444 444 444 ALA ALA B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 IHS 1 500 500 IHS IHS A . D 3 NAG 1 1082 1082 NAG NAG A . E 3 NAG 1 1184 1184 NAG NAG A . F 3 NAG 1 1316 1316 NAG NAG A . G 3 NAG 1 1353 1353 NAG NAG A . H 2 IHS 1 500 500 IHS IHS B . I 3 NAG 1 1082 1082 NAG NAG B . J 3 NAG 1 1184 1184 NAG NAG B . K 3 NAG 1 1316 1316 NAG NAG B . L 3 NAG 1 1353 1353 NAG NAG B . M 4 HOH 1 445 3 HOH HOH A . M 4 HOH 2 446 5 HOH HOH A . M 4 HOH 3 447 8 HOH HOH A . M 4 HOH 4 448 9 HOH HOH A . M 4 HOH 5 449 10 HOH HOH A . M 4 HOH 6 450 12 HOH HOH A . M 4 HOH 7 451 15 HOH HOH A . M 4 HOH 8 452 20 HOH HOH A . M 4 HOH 9 453 22 HOH HOH A . M 4 HOH 10 454 27 HOH HOH A . M 4 HOH 11 455 28 HOH HOH A . M 4 HOH 12 456 32 HOH HOH A . M 4 HOH 13 457 33 HOH HOH A . M 4 HOH 14 458 37 HOH HOH A . M 4 HOH 15 459 39 HOH HOH A . M 4 HOH 16 460 41 HOH HOH A . M 4 HOH 17 461 43 HOH HOH A . M 4 HOH 18 462 44 HOH HOH A . M 4 HOH 19 463 47 HOH HOH A . M 4 HOH 20 464 48 HOH HOH A . M 4 HOH 21 465 51 HOH HOH A . M 4 HOH 22 466 55 HOH HOH A . M 4 HOH 23 467 56 HOH HOH A . M 4 HOH 24 468 59 HOH HOH A . M 4 HOH 25 469 60 HOH HOH A . M 4 HOH 26 470 64 HOH HOH A . M 4 HOH 27 471 66 HOH HOH A . M 4 HOH 28 472 67 HOH HOH A . M 4 HOH 29 473 68 HOH HOH A . M 4 HOH 30 474 71 HOH HOH A . M 4 HOH 31 475 72 HOH HOH A . M 4 HOH 32 476 74 HOH HOH A . M 4 HOH 33 477 77 HOH HOH A . M 4 HOH 34 478 83 HOH HOH A . M 4 HOH 35 479 87 HOH HOH A . M 4 HOH 36 480 88 HOH HOH A . M 4 HOH 37 481 89 HOH HOH A . M 4 HOH 38 482 96 HOH HOH A . M 4 HOH 39 483 97 HOH HOH A . M 4 HOH 40 484 98 HOH HOH A . M 4 HOH 41 485 100 HOH HOH A . M 4 HOH 42 486 101 HOH HOH A . M 4 HOH 43 487 103 HOH HOH A . M 4 HOH 44 488 104 HOH HOH A . M 4 HOH 45 489 105 HOH HOH A . M 4 HOH 46 490 106 HOH HOH A . M 4 HOH 47 491 107 HOH HOH A . M 4 HOH 48 492 108 HOH HOH A . M 4 HOH 49 493 111 HOH HOH A . M 4 HOH 50 494 113 HOH HOH A . M 4 HOH 51 495 115 HOH HOH A . M 4 HOH 52 496 119 HOH HOH A . M 4 HOH 53 497 255 HOH HOH A . M 4 HOH 54 498 121 HOH HOH A . M 4 HOH 55 499 122 HOH HOH A . M 4 HOH 56 501 124 HOH HOH A . M 4 HOH 57 502 125 HOH HOH A . M 4 HOH 58 503 127 HOH HOH A . M 4 HOH 59 504 128 HOH HOH A . M 4 HOH 60 505 129 HOH HOH A . M 4 HOH 61 506 130 HOH HOH A . M 4 HOH 62 507 133 HOH HOH A . M 4 HOH 63 508 136 HOH HOH A . M 4 HOH 64 509 138 HOH HOH A . M 4 HOH 65 510 140 HOH HOH A . M 4 HOH 66 511 141 HOH HOH A . M 4 HOH 67 512 143 HOH HOH A . M 4 HOH 68 513 144 HOH HOH A . M 4 HOH 69 514 146 HOH HOH A . M 4 HOH 70 515 147 HOH HOH A . M 4 HOH 71 516 148 HOH HOH A . M 4 HOH 72 517 149 HOH HOH A . M 4 HOH 73 518 150 HOH HOH A . M 4 HOH 74 519 152 HOH HOH A . M 4 HOH 75 520 155 HOH HOH A . M 4 HOH 76 521 161 HOH HOH A . M 4 HOH 77 522 162 HOH HOH A . M 4 HOH 78 523 167 HOH HOH A . M 4 HOH 79 524 168 HOH HOH A . M 4 HOH 80 525 170 HOH HOH A . M 4 HOH 81 526 174 HOH HOH A . M 4 HOH 82 527 175 HOH HOH A . M 4 HOH 83 528 180 HOH HOH A . M 4 HOH 84 529 181 HOH HOH A . M 4 HOH 85 530 182 HOH HOH A . M 4 HOH 86 531 183 HOH HOH A . M 4 HOH 87 532 184 HOH HOH A . M 4 HOH 88 533 185 HOH HOH A . M 4 HOH 89 534 187 HOH HOH A . M 4 HOH 90 535 192 HOH HOH A . M 4 HOH 91 536 197 HOH HOH A . M 4 HOH 92 537 199 HOH HOH A . M 4 HOH 93 538 200 HOH HOH A . M 4 HOH 94 539 203 HOH HOH A . M 4 HOH 95 540 207 HOH HOH A . M 4 HOH 96 541 208 HOH HOH A . M 4 HOH 97 542 209 HOH HOH A . M 4 HOH 98 543 215 HOH HOH A . M 4 HOH 99 544 220 HOH HOH A . M 4 HOH 100 545 225 HOH HOH A . M 4 HOH 101 546 228 HOH HOH A . M 4 HOH 102 547 229 HOH HOH A . M 4 HOH 103 548 230 HOH HOH A . M 4 HOH 104 549 231 HOH HOH A . M 4 HOH 105 550 232 HOH HOH A . M 4 HOH 106 551 237 HOH HOH A . M 4 HOH 107 552 238 HOH HOH A . M 4 HOH 108 553 240 HOH HOH A . M 4 HOH 109 554 242 HOH HOH A . M 4 HOH 110 555 243 HOH HOH A . M 4 HOH 111 556 244 HOH HOH A . M 4 HOH 112 557 245 HOH HOH A . M 4 HOH 113 558 246 HOH HOH A . M 4 HOH 114 559 249 HOH HOH A . M 4 HOH 115 560 251 HOH HOH A . M 4 HOH 116 561 252 HOH HOH A . M 4 HOH 117 562 253 HOH HOH A . M 4 HOH 118 563 254 HOH HOH A . M 4 HOH 119 564 256 HOH HOH A . M 4 HOH 120 565 259 HOH HOH A . M 4 HOH 121 566 261 HOH HOH A . M 4 HOH 122 567 263 HOH HOH A . M 4 HOH 123 568 265 HOH HOH A . M 4 HOH 124 569 267 HOH HOH A . M 4 HOH 125 570 269 HOH HOH A . M 4 HOH 126 571 273 HOH HOH A . M 4 HOH 127 572 274 HOH HOH A . M 4 HOH 128 573 278 HOH HOH A . M 4 HOH 129 574 280 HOH HOH A . M 4 HOH 130 575 281 HOH HOH A . M 4 HOH 131 576 283 HOH HOH A . M 4 HOH 132 577 286 HOH HOH A . M 4 HOH 133 578 289 HOH HOH A . M 4 HOH 134 579 290 HOH HOH A . M 4 HOH 135 580 292 HOH HOH A . M 4 HOH 136 581 299 HOH HOH A . M 4 HOH 137 582 300 HOH HOH A . M 4 HOH 138 583 301 HOH HOH A . M 4 HOH 139 584 304 HOH HOH A . M 4 HOH 140 585 306 HOH HOH A . M 4 HOH 141 586 307 HOH HOH A . M 4 HOH 142 587 311 HOH HOH A . M 4 HOH 143 588 312 HOH HOH A . M 4 HOH 144 589 305 HOH HOH A . M 4 HOH 145 590 316 HOH HOH A . M 4 HOH 146 591 320 HOH HOH A . M 4 HOH 147 592 323 HOH HOH A . M 4 HOH 148 593 325 HOH HOH A . M 4 HOH 149 594 326 HOH HOH A . M 4 HOH 150 595 327 HOH HOH A . M 4 HOH 151 596 330 HOH HOH A . M 4 HOH 152 597 331 HOH HOH A . M 4 HOH 153 598 332 HOH HOH A . M 4 HOH 154 599 336 HOH HOH A . M 4 HOH 155 600 339 HOH HOH A . M 4 HOH 156 601 341 HOH HOH A . M 4 HOH 157 602 344 HOH HOH A . M 4 HOH 158 603 347 HOH HOH A . M 4 HOH 159 604 348 HOH HOH A . M 4 HOH 160 605 350 HOH HOH A . M 4 HOH 161 606 351 HOH HOH A . M 4 HOH 162 607 355 HOH HOH A . M 4 HOH 163 608 357 HOH HOH A . M 4 HOH 164 609 358 HOH HOH A . M 4 HOH 165 610 359 HOH HOH A . M 4 HOH 166 611 362 HOH HOH A . M 4 HOH 167 612 366 HOH HOH A . M 4 HOH 168 613 367 HOH HOH A . M 4 HOH 169 614 369 HOH HOH A . M 4 HOH 170 615 370 HOH HOH A . M 4 HOH 171 616 373 HOH HOH A . M 4 HOH 172 617 375 HOH HOH A . M 4 HOH 173 618 379 HOH HOH A . M 4 HOH 174 619 380 HOH HOH A . M 4 HOH 175 620 381 HOH HOH A . M 4 HOH 176 621 382 HOH HOH A . M 4 HOH 177 622 383 HOH HOH A . M 4 HOH 178 623 385 HOH HOH A . M 4 HOH 179 624 389 HOH HOH A . M 4 HOH 180 625 391 HOH HOH A . M 4 HOH 181 626 392 HOH HOH A . M 4 HOH 182 627 395 HOH HOH A . M 4 HOH 183 628 399 HOH HOH A . M 4 HOH 184 629 406 HOH HOH A . M 4 HOH 185 630 313 HOH HOH A . N 4 HOH 1 445 4 HOH HOH B . N 4 HOH 2 446 6 HOH HOH B . N 4 HOH 3 447 7 HOH HOH B . N 4 HOH 4 448 11 HOH HOH B . N 4 HOH 5 449 13 HOH HOH B . N 4 HOH 6 450 14 HOH HOH B . N 4 HOH 7 451 16 HOH HOH B . N 4 HOH 8 452 17 HOH HOH B . N 4 HOH 9 453 19 HOH HOH B . N 4 HOH 10 454 21 HOH HOH B . N 4 HOH 11 455 23 HOH HOH B . N 4 HOH 12 456 24 HOH HOH B . N 4 HOH 13 457 29 HOH HOH B . N 4 HOH 14 458 30 HOH HOH B . N 4 HOH 15 459 31 HOH HOH B . N 4 HOH 16 460 34 HOH HOH B . N 4 HOH 17 461 35 HOH HOH B . N 4 HOH 18 462 36 HOH HOH B . N 4 HOH 19 463 38 HOH HOH B . N 4 HOH 20 464 40 HOH HOH B . N 4 HOH 21 465 42 HOH HOH B . N 4 HOH 22 466 45 HOH HOH B . N 4 HOH 23 467 46 HOH HOH B . N 4 HOH 24 468 49 HOH HOH B . N 4 HOH 25 469 52 HOH HOH B . N 4 HOH 26 470 53 HOH HOH B . N 4 HOH 27 471 54 HOH HOH B . N 4 HOH 28 472 58 HOH HOH B . N 4 HOH 29 473 61 HOH HOH B . N 4 HOH 30 474 62 HOH HOH B . N 4 HOH 31 475 63 HOH HOH B . N 4 HOH 32 476 65 HOH HOH B . N 4 HOH 33 477 69 HOH HOH B . N 4 HOH 34 478 70 HOH HOH B . N 4 HOH 35 479 73 HOH HOH B . N 4 HOH 36 480 75 HOH HOH B . N 4 HOH 37 481 76 HOH HOH B . N 4 HOH 38 482 78 HOH HOH B . N 4 HOH 39 483 79 HOH HOH B . N 4 HOH 40 484 80 HOH HOH B . N 4 HOH 41 485 82 HOH HOH B . N 4 HOH 42 486 85 HOH HOH B . N 4 HOH 43 487 86 HOH HOH B . N 4 HOH 44 488 91 HOH HOH B . N 4 HOH 45 489 92 HOH HOH B . N 4 HOH 46 490 93 HOH HOH B . N 4 HOH 47 491 95 HOH HOH B . N 4 HOH 48 492 109 HOH HOH B . N 4 HOH 49 493 110 HOH HOH B . N 4 HOH 50 494 112 HOH HOH B . N 4 HOH 51 495 114 HOH HOH B . N 4 HOH 52 496 116 HOH HOH B . N 4 HOH 53 497 120 HOH HOH B . N 4 HOH 54 498 126 HOH HOH B . N 4 HOH 55 499 131 HOH HOH B . N 4 HOH 56 501 134 HOH HOH B . N 4 HOH 57 502 135 HOH HOH B . N 4 HOH 58 503 137 HOH HOH B . N 4 HOH 59 504 139 HOH HOH B . N 4 HOH 60 505 142 HOH HOH B . N 4 HOH 61 506 151 HOH HOH B . N 4 HOH 62 507 153 HOH HOH B . N 4 HOH 63 508 156 HOH HOH B . N 4 HOH 64 509 158 HOH HOH B . N 4 HOH 65 510 160 HOH HOH B . N 4 HOH 66 511 163 HOH HOH B . N 4 HOH 67 512 169 HOH HOH B . N 4 HOH 68 513 171 HOH HOH B . N 4 HOH 69 514 172 HOH HOH B . N 4 HOH 70 515 173 HOH HOH B . N 4 HOH 71 516 176 HOH HOH B . N 4 HOH 72 517 178 HOH HOH B . N 4 HOH 73 518 179 HOH HOH B . N 4 HOH 74 519 186 HOH HOH B . N 4 HOH 75 520 188 HOH HOH B . N 4 HOH 76 521 189 HOH HOH B . N 4 HOH 77 522 190 HOH HOH B . N 4 HOH 78 523 191 HOH HOH B . N 4 HOH 79 524 193 HOH HOH B . N 4 HOH 80 525 195 HOH HOH B . N 4 HOH 81 526 196 HOH HOH B . N 4 HOH 82 527 202 HOH HOH B . N 4 HOH 83 528 206 HOH HOH B . N 4 HOH 84 529 211 HOH HOH B . N 4 HOH 85 530 212 HOH HOH B . N 4 HOH 86 531 214 HOH HOH B . N 4 HOH 87 532 216 HOH HOH B . N 4 HOH 88 533 217 HOH HOH B . N 4 HOH 89 534 219 HOH HOH B . N 4 HOH 90 535 222 HOH HOH B . N 4 HOH 91 536 223 HOH HOH B . N 4 HOH 92 537 224 HOH HOH B . N 4 HOH 93 538 227 HOH HOH B . N 4 HOH 94 539 233 HOH HOH B . N 4 HOH 95 540 234 HOH HOH B . N 4 HOH 96 541 235 HOH HOH B . N 4 HOH 97 542 236 HOH HOH B . N 4 HOH 98 543 239 HOH HOH B . N 4 HOH 99 544 241 HOH HOH B . N 4 HOH 100 545 247 HOH HOH B . N 4 HOH 101 546 250 HOH HOH B . N 4 HOH 102 547 117 HOH HOH B . N 4 HOH 103 548 257 HOH HOH B . N 4 HOH 104 549 258 HOH HOH B . N 4 HOH 105 550 260 HOH HOH B . N 4 HOH 106 551 266 HOH HOH B . N 4 HOH 107 552 268 HOH HOH B . N 4 HOH 108 553 270 HOH HOH B . N 4 HOH 109 554 271 HOH HOH B . N 4 HOH 110 555 272 HOH HOH B . N 4 HOH 111 556 275 HOH HOH B . N 4 HOH 112 557 276 HOH HOH B . N 4 HOH 113 558 277 HOH HOH B . N 4 HOH 114 559 279 HOH HOH B . N 4 HOH 115 560 282 HOH HOH B . N 4 HOH 116 561 285 HOH HOH B . N 4 HOH 117 562 287 HOH HOH B . N 4 HOH 118 563 288 HOH HOH B . N 4 HOH 119 564 293 HOH HOH B . N 4 HOH 120 565 294 HOH HOH B . N 4 HOH 121 566 295 HOH HOH B . N 4 HOH 122 567 296 HOH HOH B . N 4 HOH 123 568 303 HOH HOH B . N 4 HOH 124 569 345 HOH HOH B . N 4 HOH 125 570 308 HOH HOH B . N 4 HOH 126 571 309 HOH HOH B . N 4 HOH 127 572 310 HOH HOH B . N 4 HOH 128 574 318 HOH HOH B . N 4 HOH 129 575 319 HOH HOH B . N 4 HOH 130 576 321 HOH HOH B . N 4 HOH 131 577 322 HOH HOH B . N 4 HOH 132 578 324 HOH HOH B . N 4 HOH 133 579 328 HOH HOH B . N 4 HOH 134 580 329 HOH HOH B . N 4 HOH 135 581 333 HOH HOH B . N 4 HOH 136 582 334 HOH HOH B . N 4 HOH 137 583 335 HOH HOH B . N 4 HOH 138 584 337 HOH HOH B . N 4 HOH 139 585 338 HOH HOH B . N 4 HOH 140 586 340 HOH HOH B . N 4 HOH 141 587 342 HOH HOH B . N 4 HOH 142 588 343 HOH HOH B . N 4 HOH 143 589 315 HOH HOH B . N 4 HOH 144 590 346 HOH HOH B . N 4 HOH 145 591 349 HOH HOH B . N 4 HOH 146 592 352 HOH HOH B . N 4 HOH 147 593 353 HOH HOH B . N 4 HOH 148 594 354 HOH HOH B . N 4 HOH 149 595 356 HOH HOH B . N 4 HOH 150 596 360 HOH HOH B . N 4 HOH 151 597 361 HOH HOH B . N 4 HOH 152 598 363 HOH HOH B . N 4 HOH 153 599 364 HOH HOH B . N 4 HOH 154 600 365 HOH HOH B . N 4 HOH 155 601 368 HOH HOH B . N 4 HOH 156 602 371 HOH HOH B . N 4 HOH 157 603 372 HOH HOH B . N 4 HOH 158 604 374 HOH HOH B . N 4 HOH 159 605 376 HOH HOH B . N 4 HOH 160 606 377 HOH HOH B . N 4 HOH 161 607 378 HOH HOH B . N 4 HOH 162 608 384 HOH HOH B . N 4 HOH 163 609 386 HOH HOH B . N 4 HOH 164 610 387 HOH HOH B . N 4 HOH 165 611 388 HOH HOH B . N 4 HOH 166 612 390 HOH HOH B . N 4 HOH 167 613 393 HOH HOH B . N 4 HOH 168 614 394 HOH HOH B . N 4 HOH 169 615 396 HOH HOH B . N 4 HOH 170 616 397 HOH HOH B . N 4 HOH 171 617 398 HOH HOH B . N 4 HOH 172 618 400 HOH HOH B . N 4 HOH 173 619 401 HOH HOH B . N 4 HOH 174 620 402 HOH HOH B . N 4 HOH 175 621 403 HOH HOH B . N 4 HOH 176 622 404 HOH HOH B . N 4 HOH 177 623 405 HOH HOH B . N 4 HOH 178 624 407 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 82 A ASN 82 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 184 A ASN 184 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 316 A ASN 316 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 353 A ASN 353 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 82 B ASN 82 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 184 B ASN 184 ? ASN 'GLYCOSYLATION SITE' 7 B ASN 316 B ASN 316 ? ASN 'GLYCOSYLATION SITE' 8 B ASN 353 B ASN 353 ? ASN 'GLYCOSYLATION SITE' # loop_ _pdbx_struct_assembly.id _pdbx_struct_assembly.details _pdbx_struct_assembly.method_details _pdbx_struct_assembly.oligomeric_details _pdbx_struct_assembly.oligomeric_count 1 author_and_software_defined_assembly PISA monomeric 1 2 author_and_software_defined_assembly PISA monomeric 1 # loop_ _pdbx_struct_assembly_gen.assembly_id _pdbx_struct_assembly_gen.oper_expression _pdbx_struct_assembly_gen.asym_id_list 1 1 A,C,D,E,F,G,M 2 1 B,H,I,J,K,L,N # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2010-06-30 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # _pdbx_audit_revision_group.ordinal 1 _pdbx_audit_revision_group.revision_ordinal 2 _pdbx_audit_revision_group.data_content_type 'Structure model' _pdbx_audit_revision_group.group 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal Blu-Ice 'data collection' . ? 1 REFMAC refinement 5.5.0102 ? 2 MOSFLM 'data reduction' . ? 3 SCALA 'data scaling' . ? 4 # loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 OD1 B ASP 260 ? ? O B HOH 558 ? ? 2.14 2 1 OE1 A GLU 364 ? ? O A HOH 554 ? ? 2.18 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 NE A ARG 129 ? ? CZ A ARG 129 ? ? NH2 A ARG 129 ? ? 116.16 120.30 -4.14 0.50 N 2 1 NE B ARG 129 ? ? CZ B ARG 129 ? ? NH2 B ARG 129 ? ? 115.85 120.30 -4.45 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PHE A 31 ? ? -39.49 133.23 2 1 SER A 99 ? ? -140.68 19.00 3 1 ASP A 103 ? ? 71.06 -42.45 4 1 ASP A 188 ? ? -165.64 77.10 5 1 PHE A 212 ? ? -145.84 -22.25 6 1 LEU A 224 ? ? -110.11 75.80 7 1 THR A 313 ? ? -103.49 -96.63 8 1 ASN A 329 ? ? -140.36 44.98 9 1 THR A 331 ? ? 67.95 -42.53 10 1 SER A 337 ? ? -161.26 -168.41 11 1 THR A 377 ? ? -124.30 -52.93 12 1 ASP A 405 ? ? 81.89 2.48 13 1 LEU A 430 ? ? -90.59 40.13 14 1 PHE B 31 ? ? -37.23 132.02 15 1 SER B 99 ? ? -140.57 15.23 16 1 ASP B 103 ? ? 68.20 -42.68 17 1 ASP B 188 ? ? -164.79 83.57 18 1 PHE B 212 ? ? -140.60 -24.52 19 1 LEU B 224 ? ? -108.40 79.00 20 1 THR B 313 ? ? -107.93 -94.45 21 1 ASN B 329 ? ? -140.30 43.25 22 1 THR B 331 ? ? 67.79 -42.26 23 1 ASP B 405 ? ? 83.72 2.57 24 1 LEU B 430 ? ? -86.32 36.71 # loop_ _pdbx_unobs_or_zero_occ_atoms.id _pdbx_unobs_or_zero_occ_atoms.PDB_model_num _pdbx_unobs_or_zero_occ_atoms.polymer_flag _pdbx_unobs_or_zero_occ_atoms.occupancy_flag _pdbx_unobs_or_zero_occ_atoms.auth_asym_id _pdbx_unobs_or_zero_occ_atoms.auth_comp_id _pdbx_unobs_or_zero_occ_atoms.auth_seq_id _pdbx_unobs_or_zero_occ_atoms.PDB_ins_code _pdbx_unobs_or_zero_occ_atoms.auth_atom_id _pdbx_unobs_or_zero_occ_atoms.label_alt_id _pdbx_unobs_or_zero_occ_atoms.label_asym_id _pdbx_unobs_or_zero_occ_atoms.label_comp_id _pdbx_unobs_or_zero_occ_atoms.label_seq_id _pdbx_unobs_or_zero_occ_atoms.label_atom_id 1 1 Y 1 A GLU 199 ? CG ? A GLU 199 CG 2 1 Y 1 A GLU 199 ? CD ? A GLU 199 CD 3 1 Y 1 A GLU 199 ? OE1 ? A GLU 199 OE1 4 1 Y 1 A GLU 199 ? OE2 ? A GLU 199 OE2 5 1 Y 1 A GLN 392 ? CG ? A GLN 392 CG 6 1 Y 1 A GLN 392 ? CD ? A GLN 392 CD 7 1 Y 1 A GLN 392 ? OE1 ? A GLN 392 OE1 8 1 Y 1 A GLN 392 ? NE2 ? A GLN 392 NE2 9 1 Y 1 A GLN 395 ? CG ? A GLN 395 CG 10 1 Y 1 A GLN 395 ? CD ? A GLN 395 CD 11 1 Y 1 A GLN 395 ? OE1 ? A GLN 395 OE1 12 1 Y 1 A GLN 395 ? NE2 ? A GLN 395 NE2 13 1 Y 1 B GLN 155 ? CG ? B GLN 155 CG 14 1 Y 1 B GLN 155 ? CD ? B GLN 155 CD 15 1 Y 1 B GLN 155 ? OE1 ? B GLN 155 OE1 16 1 Y 1 B GLN 155 ? NE2 ? B GLN 155 NE2 17 1 Y 1 B LYS 254 ? CG ? B LYS 254 CG 18 1 Y 1 B LYS 254 ? CD ? B LYS 254 CD 19 1 Y 1 B LYS 254 ? CE ? B LYS 254 CE 20 1 Y 1 B LYS 254 ? NZ ? B LYS 254 NZ # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ALA 1 ? A ALA 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A ARG 3 ? A ARG 3 4 1 Y 1 A ASN 4 ? A ASN 4 5 1 Y 1 A GLN 5 ? A GLN 5 6 1 Y 1 A SER 6 ? A SER 6 7 1 Y 1 B ALA 1 ? B ALA 1 8 1 Y 1 B SER 2 ? B SER 2 9 1 Y 1 B ARG 3 ? B ARG 3 10 1 Y 1 B ASN 4 ? B ASN 4 11 1 Y 1 B GLN 5 ? B GLN 5 12 1 Y 1 B SER 6 ? B SER 6 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 D-MYO-INOSITOL-HEXASULPHATE IHS 3 N-ACETYL-D-GLUCOSAMINE NAG 4 water HOH #