data_3BVT # _entry.id 3BVT # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3BVT RCSB RCSB046018 WWPDB D_1000046018 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1HTY 'dGMII + Tris' unspecified PDB 1HWW 'dGMII + Swainsonine' unspecified PDB 1HXK 'dGMII + Deoxymannojirimicin' unspecified PDB 1PS2 'dGMII + Kifunensine' unspecified PDB 1QWN 'dGMII + 5fluoro-Gulosylfluoride' unspecified PDB 1QX1 'dGMII + 2F-mannosylF' unspecified PDB 1R33 'dGMII + 5-thio-D-mannopyranosylamine' unspecified PDB 1R34 'dGMII + 5-thio-D-mannopyranosylamidinium salt' unspecified PDB 1TQS 'dGMII + Salacinol' unspecified PDB 1TQT 'dGMII + Diastereomer of Salacinol' unspecified PDB 1TQU 'dGMII + Ghavamiol' unspecified PDB 1TQV 'dGMII + Blintol' unspecified PDB 1TQW 'dGMII + Blintol Diastereomer' unspecified PDB 2ALW 'dGMII + Noeuromycin' unspecified PDB 2F18 'dGMII + (2R,3R,4S)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' unspecified PDB 2F1A 'dGMII + (2R,3R,4S)-2-({[(1S)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' unspecified PDB 2F1B 'dGMII + (2R,3R,4S,5R)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)-5-methylpyrrolidine-3,4-diol' unspecified PDB 2F7O 'dGMII + Mannostatin A' unspecified PDB 2F7P 'dGMII + Benzyl-mannostatin A' unspecified PDB 2F7Q 'dGMII + Aminocyclopentitetrol' unspecified PDB 2F7R 'dGMII + Benzyl-aminocyclopentitetrol' unspecified PDB 3BUB 'dGMII empty active site' unspecified PDB 3BUD 'dGMII nucleophile mutant D204A empty active site' unspecified PDB 3BUI 'dGMII nucleophile mutant D204A + tris' unspecified PDB 3BUP 'dGMII acid-base catalyst mutant D341N + mannose' unspecified PDB 3BUQ 'dGMII nucleophile mutant D204A + mannose' unspecified PDB 3BVU 'dGMII_D204A + substrate WZ2' unspecified PDB 3BVV 'dGMII_D204A + substrate WZ3' unspecified PDB 3BVW 'dGMII_D204A + substrate WZ4' unspecified PDB 3BVX 'dGMII_D204A + substrate WZ5' unspecified # _pdbx_database_status.entry_id 3BVT _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2008-01-07 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Kuntz, D.A.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title ;Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. ; _citation.journal_abbrev J.Am.Chem.Soc. _citation.journal_volume 130 _citation.page_first 8975 _citation.page_last 8983 _citation.year 2008 _citation.journal_id_ASTM JACSAT _citation.country US _citation.journal_id_ISSN 0002-7863 _citation.journal_id_CSD 0004 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 18558690 _citation.pdbx_database_id_DOI 10.1021/ja711248y # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Zhong, W.' 1 primary 'Kuntz, D.A.' 2 primary 'Ember, B.' 3 primary 'Singh, H.' 4 primary 'Moremen, K.W.' 5 primary 'Rose, D.R.' 6 primary 'Boons, G.J.' 7 # _cell.length_a 69.040 _cell.length_b 109.847 _cell.length_c 138.627 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3BVT _cell.pdbx_unique_axis ? _cell.Z_PDB 4 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.entry_id 3BVT _symmetry.Int_Tables_number 19 _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Alpha-mannosidase 2' 119657.602 1 3.2.1.114 D204A 'Catalytic domain; UNP residues 76-1108' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'PHOSPHATE ION' 94.971 1 ? ? ? ? 4 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 5 non-polymer syn '(4R)-2-METHYLPENTANE-2,4-DIOL' 118.174 1 ? ? ? ? 6 non-polymer syn 'methyl 3-S-alpha-D-mannopyranosyl-3-thio-alpha-D-mannopyranoside' 372.389 1 ? ? ? ? 7 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 2 ? ? ? ? 8 water nat water 18.015 1453 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Alpha-mannosidase II, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIAPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIAPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ALA n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASP n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'Fruit fly' _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'alpha-Man-II, GmII' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id ? _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id ? _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMTBIP_NHIS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MAN2_DROME _struct_ref.pdbx_db_accession Q24451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHND PGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEAN SHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWD NKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN VLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSD NYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE ALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFY VSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLL RKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPN GPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQ FIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIY RLVLEKVNNCVRPSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKT QRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS ; _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3BVT _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q24451 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3BVT ARG A 1 ? UNP Q24451 ? ? 'EXPRESSION TAG' 1 1 1 3BVT SER A 2 ? UNP Q24451 ? ? 'EXPRESSION TAG' 2 2 1 3BVT SER A 3 ? UNP Q24451 ? ? 'EXPRESSION TAG' 3 3 1 3BVT HIS A 4 ? UNP Q24451 ? ? 'EXPRESSION TAG' 4 4 1 3BVT HIS A 5 ? UNP Q24451 ? ? 'EXPRESSION TAG' 5 5 1 3BVT HIS A 6 ? UNP Q24451 ? ? 'EXPRESSION TAG' 6 6 1 3BVT HIS A 7 ? UNP Q24451 ? ? 'EXPRESSION TAG' 7 7 1 3BVT HIS A 8 ? UNP Q24451 ? ? 'EXPRESSION TAG' 8 8 1 3BVT HIS A 9 ? UNP Q24451 ? ? 'EXPRESSION TAG' 9 9 1 3BVT GLY A 10 ? UNP Q24451 ? ? 'EXPRESSION TAG' 10 10 1 3BVT GLU A 11 ? UNP Q24451 ? ? 'EXPRESSION TAG' 11 11 1 3BVT PHE A 12 ? UNP Q24451 ? ? 'EXPRESSION TAG' 12 12 1 3BVT ALA A 204 ? UNP Q24451 ASP 267 ENGINEERED 204 13 1 3BVT LYS A 907 ? UNP Q24451 GLU 970 'SEE REMARK 999' 907 14 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 MRD non-polymer . '(4R)-2-METHYLPENTANE-2,4-DIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PO4 non-polymer . 'PHOSPHATE ION' ? 'O4 P -3' 94.971 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 WZ1 non-polymer . 'methyl 3-S-alpha-D-mannopyranosyl-3-thio-alpha-D-mannopyranoside' 'Methyl(alpha-D-mannopyranosyl)-(1->3)-S-alpha-D-mannopyranoside' 'C13 H24 O10 S' 372.389 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.crystals_number 1 _exptl.entry_id 3BVT _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 2.20 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 44.00 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details ;TRIS, NACL, PEG6000, MPD. Crystals washed in phosphate buffered reservoir solution before soaking with substrate for 24 hrs, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K ; _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2006-06-01 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.977 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE A1' _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline A1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.977 # _reflns.entry_id 3BVT _reflns.d_resolution_high 1.300 _reflns.d_resolution_low 20.000 _reflns.number_obs 256264 _reflns.pdbx_Rmerge_I_obs 0.068 _reflns.pdbx_netI_over_sigmaI 12.900 _reflns.pdbx_chi_squared 1.058 _reflns.percent_possible_obs 99.800 _reflns.observed_criterion_sigma_F 0 _reflns.observed_criterion_sigma_I 0 _reflns.number_all 256778 _reflns.pdbx_Rsym_value ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 6.7 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.30 _reflns_shell.d_res_low 1.33 _reflns_shell.number_measured_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_unique_obs ? _reflns_shell.Rmerge_I_obs 0.887 _reflns_shell.meanI_over_sigI_obs 2.6 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_chi_squared 1.216 _reflns_shell.pdbx_redundancy 5.5 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 16843 _reflns_shell.percent_possible_all 99.60 _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 3BVT _refine.ls_d_res_high 1.300 _refine.ls_d_res_low 19.840 _refine.pdbx_ls_sigma_F 0.00 _refine.ls_percent_reflns_obs 99.650 _refine.ls_number_reflns_obs 256139 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.ls_R_factor_obs 0.174 _refine.ls_R_factor_R_work 0.174 _refine.ls_R_factor_R_free 0.192 _refine.ls_percent_reflns_R_free 1.500 _refine.ls_number_reflns_R_free 3801 _refine.B_iso_mean 16.953 _refine.aniso_B[1][1] 0.000 _refine.aniso_B[2][2] 0.000 _refine.aniso_B[3][3] 0.000 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.correlation_coeff_Fo_to_Fc 0.970 _refine.correlation_coeff_Fo_to_Fc_free 0.966 _refine.pdbx_overall_ESU_R 0.049 _refine.pdbx_overall_ESU_R_Free 0.050 _refine.overall_SU_ML 0.035 _refine.overall_SU_B 0.807 _refine.solvent_model_details MASK _refine.pdbx_solvent_vdw_probe_radii 1.200 _refine.pdbx_solvent_ion_probe_radii 0.800 _refine.pdbx_solvent_shrinkage_radii 0.800 _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_ls_sigma_I ? _refine.ls_number_reflns_all 257039 _refine.ls_R_factor_all ? _refine.ls_redundancy_reflns_obs ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_starting_model 'PDB entry 1HTY' _refine.pdbx_stereochem_target_val_spec_case ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.pdbx_isotropic_thermal_model ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 3BVT _refine_analyze.Luzzati_coordinate_error_obs 0.141 _refine_analyze.Luzzati_sigma_a_obs ? _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8194 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 68 _refine_hist.number_atoms_solvent 1453 _refine_hist.number_atoms_total 9715 _refine_hist.d_res_high 1.300 _refine_hist.d_res_low 19.840 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 8777 0.014 0.021 ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 11979 1.520 1.943 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 1089 6.087 5.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 432 37.004 23.681 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 1488 12.160 15.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 60 18.705 15.000 ? 'X-RAY DIFFRACTION' ? r_chiral_restr 1277 0.101 0.200 ? 'X-RAY DIFFRACTION' ? r_gen_planes_refined 6816 0.008 0.020 ? 'X-RAY DIFFRACTION' ? r_nbd_refined 4324 0.203 0.200 ? 'X-RAY DIFFRACTION' ? r_nbtor_refined 6031 0.311 0.200 ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 1242 0.142 0.200 ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined 1 0.019 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 82 0.212 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 69 0.116 0.200 ? 'X-RAY DIFFRACTION' ? r_mcbond_it 5361 1.031 1.500 ? 'X-RAY DIFFRACTION' ? r_mcangle_it 8534 1.636 2.000 ? 'X-RAY DIFFRACTION' ? r_scbond_it 3868 2.320 3.000 ? 'X-RAY DIFFRACTION' ? r_scangle_it 3421 3.539 4.500 ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.d_res_high 1.30 _refine_ls_shell.d_res_low 1.335 _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.percent_reflns_obs 97.360 _refine_ls_shell.number_reflns_R_work 17986 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.256 _refine_ls_shell.R_factor_R_free 0.283 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 274 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.number_reflns_all 18260 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 3BVT _struct.title ;GOLGI MANNOSIDASE II D204A catalytic nucleophile mutant complex with Methyl (alpha-D-mannopyranosyl)-(1->3)-S-alpha-D-mannopyranoside ; _struct.pdbx_descriptor 'Alpha-mannosidase 2 (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3BVT _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'FAMILY 38 GLYCOYSL HYDROLASE, Glycosidase, Golgi apparatus, Membrane, Signal-anchor, Transmembrane, HYDROLASE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? G N N 7 ? H N N 7 ? I N N 8 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? HIS A 139 ? GLU A 130 HIS A 139 1 ? 10 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? MET A 290 ? GLN A 284 MET A 290 5 ? 7 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.053 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.027 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.096 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.051 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 1.999 ? metalc1 metalc ? ? A HIS 90 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 90 A ZN 1048 1_555 ? ? ? ? ? ? ? 2.075 ? metalc2 metalc ? ? A ASP 92 OD1 ? ? ? 1_555 D ZN . ZN ? ? A ASP 92 A ZN 1048 1_555 ? ? ? ? ? ? ? 2.000 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 1046 1_555 ? ? ? ? ? ? ? 1.485 ? metalc3 metalc ? ? A HIS 471 NE2 ? ? ? 1_555 D ZN . ZN ? ? A HIS 471 A ZN 1048 1_555 ? ? ? ? ? ? ? 2.065 ? metalc4 metalc ? ? D ZN . ZN ? ? ? 1_555 F WZ1 . O32 ? ? A ZN 1048 A WZ1 1050 1_555 ? ? ? ? ? ? ? 2.129 ? metalc5 metalc ? ? D ZN . ZN ? ? ? 1_555 F WZ1 . O22 ? ? A ZN 1048 A WZ1 1050 1_555 ? ? ? ? ? ? ? 2.229 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 -4.77 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 -6.29 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 6 ? E ? 5 ? F ? 5 ? G ? 12 ? H ? 5 ? I ? 8 ? J ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel D 4 5 ? anti-parallel D 5 6 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel F 1 2 ? parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? anti-parallel G 5 6 ? anti-parallel G 6 7 ? anti-parallel G 7 8 ? anti-parallel G 8 9 ? anti-parallel G 9 10 ? anti-parallel G 10 11 ? anti-parallel G 11 12 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel I 5 6 ? anti-parallel I 6 7 ? anti-parallel I 7 8 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASP A 341 ? VAL A 333 ASP A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 D 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 D 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 D 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 D 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 D 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 F 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 F 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 F 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 F 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 F 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 G 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 G 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 G 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 G 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 G 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 G 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 G 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 G 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 G 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 G 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 G 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 G 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 H 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 H 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 H 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 H 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 H 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 I 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 I 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 I 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 I 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 J 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 J 2 GLN A 973 ? ARG A 981 ? GLN A 973 ARG A 981 J 3 THR A 1036 ? HIS A 1043 ? THR A 1036 HIS A 1043 J 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 J 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O SER A 401 ? O SER A 401 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O LEU A 225 ? O LEU A 225 N ALA A 202 ? N ALA A 202 B 1 2 O LEU A 334 ? O LEU A 334 N LYS A 82 ? N LYS A 82 B 2 3 N VAL A 85 ? N VAL A 85 O GLN A 375 ? O GLN A 375 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 D 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 D 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 D 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 D 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 F 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 F 2 3 N ARG A 565 ? N ARG A 565 O VAL A 624 ? O VAL A 624 F 3 4 O GLN A 610 ? O GLN A 610 N SER A 597 ? N SER A 597 F 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 G 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 G 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 G 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 G 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 G 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 G 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 G 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 G 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 G 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 G 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 G 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 H 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 H 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 H 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 H 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 I 5 6 N ILE A 790 ? N ILE A 790 O GLN A 866 ? O GLN A 866 I 6 7 O MET A 865 ? O MET A 865 N GLY A 853 ? N GLY A 853 I 7 8 O GLY A 854 ? O GLY A 854 N TYR A 829 ? N TYR A 829 J 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 J 2 3 N LEU A 979 ? N LEU A 979 O ALA A 1037 ? O ALA A 1037 J 3 4 O SER A 1042 ? O SER A 1042 N ALA A 1007 ? N ALA A 1007 J 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG A 1046' AC2 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE PO4 A 1047' AC3 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE ZN A 1048' AC4 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE MRD A 1049' AC5 Software ? ? ? ? 18 'BINDING SITE FOR RESIDUE WZ1 A 1050' AC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE MPD A 1051' AC7 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE MPD A 1052' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 4 LYS A 154 ? LYS A 154 . ? 1_555 ? 2 AC1 4 ASN A 194 ? ASN A 194 . ? 1_555 ? 3 AC1 4 HOH I . ? HOH A 1650 . ? 1_555 ? 4 AC1 4 HOH I . ? HOH A 1651 . ? 1_555 ? 5 AC2 9 ARG A 770 ? ARG A 770 . ? 1_555 ? 6 AC2 9 ARG A 893 ? ARG A 893 . ? 1_555 ? 7 AC2 9 SER A 924 ? SER A 924 . ? 1_555 ? 8 AC2 9 HOH I . ? HOH A 2071 . ? 1_555 ? 9 AC2 9 HOH I . ? HOH A 2084 . ? 1_555 ? 10 AC2 9 HOH I . ? HOH A 2085 . ? 1_555 ? 11 AC2 9 HOH I . ? HOH A 2087 . ? 1_555 ? 12 AC2 9 HOH I . ? HOH A 2092 . ? 1_555 ? 13 AC2 9 HOH I . ? HOH A 2099 . ? 1_555 ? 14 AC3 3 HIS A 90 ? HIS A 90 . ? 1_555 ? 15 AC3 3 ASP A 92 ? ASP A 92 . ? 1_555 ? 16 AC3 3 HIS A 471 ? HIS A 471 . ? 1_555 ? 17 AC4 7 LYS A 63 ? LYS A 63 . ? 1_555 ? 18 AC4 7 GLN A 64 ? GLN A 64 . ? 1_555 ? 19 AC4 7 HIS A 273 ? HIS A 273 . ? 1_555 ? 20 AC4 7 HOH I . ? HOH A 1166 . ? 1_555 ? 21 AC4 7 HOH I . ? HOH A 1705 . ? 1_555 ? 22 AC4 7 HOH I . ? HOH A 1707 . ? 1_555 ? 23 AC4 7 HOH I . ? HOH A 1709 . ? 1_555 ? 24 AC5 18 HIS A 90 ? HIS A 90 . ? 1_555 ? 25 AC5 18 ASP A 92 ? ASP A 92 . ? 1_555 ? 26 AC5 18 TRP A 95 ? TRP A 95 . ? 1_555 ? 27 AC5 18 ALA A 204 ? ALA A 204 . ? 1_555 ? 28 AC5 18 ARG A 228 ? ARG A 228 . ? 1_555 ? 29 AC5 18 SER A 268 ? SER A 268 . ? 1_555 ? 30 AC5 18 TYR A 269 ? TYR A 269 . ? 1_555 ? 31 AC5 18 ASP A 270 ? ASP A 270 . ? 1_555 ? 32 AC5 18 ASP A 341 ? ASP A 341 . ? 1_555 ? 33 AC5 18 TRP A 415 ? TRP A 415 . ? 1_555 ? 34 AC5 18 HIS A 471 ? HIS A 471 . ? 1_555 ? 35 AC5 18 ASP A 472 ? ASP A 472 . ? 1_555 ? 36 AC5 18 TYR A 727 ? TYR A 727 . ? 1_555 ? 37 AC5 18 GLU A 875 ? GLU A 875 . ? 1_555 ? 38 AC5 18 ARG A 876 ? ARG A 876 . ? 1_555 ? 39 AC5 18 HOH I . ? HOH A 1194 . ? 1_555 ? 40 AC5 18 HOH I . ? HOH A 1197 . ? 1_555 ? 41 AC5 18 HOH I . ? HOH A 1843 . ? 1_555 ? 42 AC6 5 TYR A 435 ? TYR A 435 . ? 1_555 ? 43 AC6 5 LEU A 494 ? LEU A 494 . ? 1_555 ? 44 AC6 5 GLN A 498 ? GLN A 498 . ? 1_555 ? 45 AC6 5 TRP A 531 ? TRP A 531 . ? 1_555 ? 46 AC6 5 HOH I . ? HOH A 1582 . ? 1_555 ? 47 AC7 5 ASP A 106 ? ASP A 106 . ? 1_555 ? 48 AC7 5 ASP A 341 ? ASP A 341 . ? 1_555 ? 49 AC7 5 HOH I . ? HOH A 1215 . ? 1_555 ? 50 AC7 5 HOH I . ? HOH A 1852 . ? 1_555 ? 51 AC7 5 HOH I . ? HOH A 1853 . ? 1_555 ? # _database_PDB_matrix.entry_id 3BVT _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.000000 _database_PDB_matrix.origx_vector[2] 0.000000 _database_PDB_matrix.origx_vector[3] 0.000000 # _atom_sites.entry_id 3BVT _atom_sites.fract_transf_matrix[1][1] 0.014484 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009104 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007214 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O P S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLN A 1 30 ? 46.912 34.412 -18.809 1.00 34.96 ? 30 GLN A N 1 ATOM 2 C CA . GLN A 1 30 ? 45.485 34.221 -19.207 1.00 34.40 ? 30 GLN A CA 1 ATOM 3 C C . GLN A 1 30 ? 44.559 35.217 -18.524 1.00 33.05 ? 30 GLN A C 1 ATOM 4 O O . GLN A 1 30 ? 44.157 35.036 -17.371 1.00 33.96 ? 30 GLN A O 1 ATOM 5 C CB . GLN A 1 30 ? 45.013 32.807 -18.914 1.00 35.00 ? 30 GLN A CB 1 ATOM 6 C CG . GLN A 1 30 ? 43.754 32.468 -19.678 1.00 37.88 ? 30 GLN A CG 1 ATOM 7 C CD . GLN A 1 30 ? 42.992 31.316 -19.069 1.00 42.15 ? 30 GLN A CD 1 ATOM 8 O OE1 . GLN A 1 30 ? 41.810 31.460 -18.739 1.00 43.68 ? 30 GLN A OE1 1 ATOM 9 N NE2 . GLN A 1 30 ? 43.656 30.167 -18.917 1.00 43.17 ? 30 GLN A NE2 1 ATOM 10 N N . CYS A 1 31 ? 44.208 36.260 -19.262 1.00 30.64 ? 31 CYS A N 1 ATOM 11 C CA . CYS A 1 31 ? 43.459 37.373 -18.710 1.00 27.88 ? 31 CYS A CA 1 ATOM 12 C C . CYS A 1 31 ? 41.972 37.079 -18.687 1.00 26.14 ? 31 CYS A C 1 ATOM 13 O O . CYS A 1 31 ? 41.450 36.475 -19.632 1.00 26.00 ? 31 CYS A O 1 ATOM 14 C CB . CYS A 1 31 ? 43.734 38.595 -19.564 1.00 27.57 ? 31 CYS A CB 1 ATOM 15 S SG . CYS A 1 31 ? 45.471 39.077 -19.466 1.00 28.18 ? 31 CYS A SG 1 ATOM 16 N N . GLN A 1 32 ? 41.296 37.510 -17.623 1.00 23.81 ? 32 GLN A N 1 ATOM 17 C CA . GLN A 1 32 ? 39.831 37.528 -17.584 1.00 22.53 ? 32 GLN A CA 1 ATOM 18 C C . GLN A 1 32 ? 39.306 38.438 -18.681 1.00 20.66 ? 32 GLN A C 1 ATOM 19 O O . GLN A 1 32 ? 39.882 39.495 -18.967 1.00 19.26 ? 32 GLN A O 1 ATOM 20 C CB . GLN A 1 32 ? 39.307 38.095 -16.262 1.00 23.35 ? 32 GLN A CB 1 ATOM 21 C CG . GLN A 1 32 ? 39.193 37.112 -15.127 1.00 26.30 ? 32 GLN A CG 1 ATOM 22 C CD . GLN A 1 32 ? 38.141 37.536 -14.087 1.00 28.65 ? 32 GLN A CD 1 ATOM 23 O OE1 . GLN A 1 32 ? 37.013 37.033 -14.104 1.00 30.18 ? 32 GLN A OE1 1 ATOM 24 N NE2 . GLN A 1 32 ? 38.509 38.464 -13.194 1.00 29.33 ? 32 GLN A NE2 1 ATOM 25 N N . ASP A 1 33 ? 38.201 38.029 -19.283 1.00 19.22 ? 33 ASP A N 1 ATOM 26 C CA . ASP A 1 33 ? 37.535 38.839 -20.298 1.00 17.83 ? 33 ASP A CA 1 ATOM 27 C C . ASP A 1 33 ? 36.601 39.814 -19.582 1.00 17.79 ? 33 ASP A C 1 ATOM 28 O O . ASP A 1 33 ? 35.656 39.394 -18.934 1.00 19.65 ? 33 ASP A O 1 ATOM 29 C CB . ASP A 1 33 ? 36.747 37.894 -21.219 1.00 18.15 ? 33 ASP A CB 1 ATOM 30 C CG . ASP A 1 33 ? 36.095 38.592 -22.389 1.00 21.10 ? 33 ASP A CG 1 ATOM 31 O OD1 . ASP A 1 33 ? 35.551 39.714 -22.248 1.00 19.86 ? 33 ASP A OD1 1 ATOM 32 O OD2 . ASP A 1 33 ? 36.005 38.019 -23.497 1.00 24.10 ? 33 ASP A OD2 1 ATOM 33 N N . VAL A 1 34 ? 36.830 41.114 -19.740 1.00 13.77 ? 34 VAL A N 1 ATOM 34 C CA . VAL A 1 34 ? 36.095 42.130 -18.973 1.00 12.16 ? 34 VAL A CA 1 ATOM 35 C C . VAL A 1 34 ? 34.890 42.680 -19.715 1.00 11.76 ? 34 VAL A C 1 ATOM 36 O O . VAL A 1 34 ? 34.184 43.547 -19.220 1.00 11.03 ? 34 VAL A O 1 ATOM 37 C CB . VAL A 1 34 ? 37.010 43.283 -18.497 1.00 11.89 ? 34 VAL A CB 1 ATOM 38 C CG1 . VAL A 1 34 ? 38.180 42.709 -17.750 1.00 13.29 ? 34 VAL A CG1 1 ATOM 39 C CG2 . VAL A 1 34 ? 37.548 44.101 -19.674 1.00 12.14 ? 34 VAL A CG2 1 ATOM 40 N N . VAL A 1 35 ? 34.629 42.127 -20.901 1.00 11.89 ? 35 VAL A N 1 ATOM 41 C CA . VAL A 1 35 ? 33.540 42.601 -21.745 1.00 11.69 ? 35 VAL A CA 1 ATOM 42 C C . VAL A 1 35 ? 32.364 41.637 -21.924 1.00 11.30 ? 35 VAL A C 1 ATOM 43 O O . VAL A 1 35 ? 31.220 42.041 -21.873 1.00 11.45 ? 35 VAL A O 1 ATOM 44 C CB . VAL A 1 35 ? 34.073 42.963 -23.138 1.00 11.20 ? 35 VAL A CB 1 ATOM 45 C CG1 . VAL A 1 35 ? 32.927 43.355 -24.099 1.00 13.21 ? 35 VAL A CG1 1 ATOM 46 C CG2 . VAL A 1 35 ? 35.139 44.074 -23.042 1.00 13.42 ? 35 VAL A CG2 1 ATOM 47 N N . GLN A 1 36 ? 32.687 40.359 -22.134 1.00 12.91 ? 36 GLN A N 1 ATOM 48 C CA . GLN A 1 36 ? 31.706 39.409 -22.689 1.00 15.16 ? 36 GLN A CA 1 ATOM 49 C C . GLN A 1 36 ? 31.042 38.499 -21.672 1.00 17.96 ? 36 GLN A C 1 ATOM 50 O O . GLN A 1 36 ? 30.070 37.817 -22.008 1.00 20.88 ? 36 GLN A O 1 ATOM 51 C CB . GLN A 1 36 ? 32.402 38.577 -23.755 1.00 14.87 ? 36 GLN A CB 1 ATOM 52 C CG . GLN A 1 36 ? 33.050 39.405 -24.830 1.00 17.09 ? 36 GLN A CG 1 ATOM 53 C CD . GLN A 1 36 ? 33.525 38.561 -25.983 1.00 17.38 ? 36 GLN A CD 1 ATOM 54 O OE1 . GLN A 1 36 ? 32.786 38.370 -26.949 1.00 20.00 ? 36 GLN A OE1 1 ATOM 55 N NE2 . GLN A 1 36 ? 34.759 38.092 -25.917 1.00 17.85 ? 36 GLN A NE2 1 ATOM 56 N N . ASP A 1 37 ? 31.538 38.482 -20.442 1.00 18.30 ? 37 ASP A N 1 ATOM 57 C CA . ASP A 1 37 ? 30.996 37.607 -19.398 1.00 19.48 ? 37 ASP A CA 1 ATOM 58 C C . ASP A 1 37 ? 30.346 38.458 -18.298 1.00 18.58 ? 37 ASP A C 1 ATOM 59 O O . ASP A 1 37 ? 31.054 39.125 -17.549 1.00 21.41 ? 37 ASP A O 1 ATOM 60 C CB . ASP A 1 37 ? 32.122 36.750 -18.779 1.00 20.38 ? 37 ASP A CB 1 ATOM 61 C CG . ASP A 1 37 ? 32.790 35.812 -19.777 1.00 23.67 ? 37 ASP A CG 1 ATOM 62 O OD1 . ASP A 1 37 ? 32.074 35.201 -20.599 1.00 27.86 ? 37 ASP A OD1 1 ATOM 63 O OD2 . ASP A 1 37 ? 34.036 35.625 -19.797 1.00 26.48 ? 37 ASP A OD2 1 ATOM 64 N N . VAL A 1 38 ? 29.028 38.419 -18.181 1.00 17.41 ? 38 VAL A N 1 ATOM 65 C CA . VAL A 1 38 ? 28.342 39.213 -17.136 1.00 16.66 ? 38 VAL A CA 1 ATOM 66 C C . VAL A 1 38 ? 28.509 38.504 -15.784 1.00 16.31 ? 38 VAL A C 1 ATOM 67 O O . VAL A 1 38 ? 28.097 37.341 -15.645 1.00 16.53 ? 38 VAL A O 1 ATOM 68 C CB . VAL A 1 38 ? 26.847 39.393 -17.444 1.00 16.66 ? 38 VAL A CB 1 ATOM 69 C CG1 . VAL A 1 38 ? 26.118 40.110 -16.304 1.00 17.44 ? 38 VAL A CG1 1 ATOM 70 C CG2 . VAL A 1 38 ? 26.637 40.073 -18.822 1.00 17.83 ? 38 VAL A CG2 1 ATOM 71 N N . PRO A 1 39 ? 29.147 39.138 -14.798 1.00 14.72 ? 39 PRO A N 1 ATOM 72 C CA . PRO A 1 39 ? 29.336 38.474 -13.500 1.00 14.00 ? 39 PRO A CA 1 ATOM 73 C C . PRO A 1 39 ? 28.015 38.126 -12.856 1.00 14.09 ? 39 PRO A C 1 ATOM 74 O O . PRO A 1 39 ? 27.036 38.833 -12.937 1.00 14.13 ? 39 PRO A O 1 ATOM 75 C CB . PRO A 1 39 ? 30.048 39.550 -12.672 1.00 14.04 ? 39 PRO A CB 1 ATOM 76 C CG . PRO A 1 39 ? 30.828 40.327 -13.715 1.00 14.19 ? 39 PRO A CG 1 ATOM 77 C CD . PRO A 1 39 ? 29.821 40.464 -14.841 1.00 14.33 ? 39 PRO A CD 1 ATOM 78 N N . ASN A 1 40 ? 27.997 36.958 -12.219 1.00 14.87 ? 40 ASN A N 1 ATOM 79 C CA . ASN A 1 40 ? 26.854 36.568 -11.429 1.00 16.08 ? 40 ASN A CA 1 ATOM 80 C C . ASN A 1 40 ? 27.112 36.929 -9.959 1.00 14.70 ? 40 ASN A C 1 ATOM 81 O O . ASN A 1 40 ? 28.008 36.349 -9.313 1.00 16.10 ? 40 ASN A O 1 ATOM 82 C CB . ASN A 1 40 ? 26.589 35.068 -11.630 1.00 17.87 ? 40 ASN A CB 1 ATOM 83 C CG . ASN A 1 40 ? 25.469 34.548 -10.779 1.00 22.11 ? 40 ASN A CG 1 ATOM 84 O OD1 . ASN A 1 40 ? 24.463 35.223 -10.553 1.00 27.06 ? 40 ASN A OD1 1 ATOM 85 N ND2 . ASN A 1 40 ? 25.629 33.315 -10.304 1.00 28.32 ? 40 ASN A ND2 1 ATOM 86 N N . VAL A 1 41 ? 26.384 37.938 -9.487 1.00 13.49 ? 41 VAL A N 1 ATOM 87 C CA . VAL A 1 41 ? 26.546 38.421 -8.100 1.00 12.38 ? 41 VAL A CA 1 ATOM 88 C C . VAL A 1 41 ? 25.205 38.399 -7.401 1.00 12.79 ? 41 VAL A C 1 ATOM 89 O O . VAL A 1 41 ? 24.146 38.514 -8.038 1.00 13.18 ? 41 VAL A O 1 ATOM 90 C CB . VAL A 1 41 ? 27.186 39.856 -8.061 1.00 11.75 ? 41 VAL A CB 1 ATOM 91 C CG1 . VAL A 1 41 ? 28.610 39.780 -8.567 1.00 13.22 ? 41 VAL A CG1 1 ATOM 92 C CG2 . VAL A 1 41 ? 26.335 40.851 -8.874 1.00 12.47 ? 41 VAL A CG2 1 ATOM 93 N N . ASP A 1 42 ? 25.203 38.272 -6.083 1.00 11.86 ? 42 ASP A N 1 ATOM 94 C CA . ASP A 1 42 ? 23.951 38.315 -5.339 1.00 11.70 ? 42 ASP A CA 1 ATOM 95 C C . ASP A 1 42 ? 23.256 39.670 -5.384 1.00 11.42 ? 42 ASP A C 1 ATOM 96 O O . ASP A 1 42 ? 22.044 39.756 -5.437 1.00 12.58 ? 42 ASP A O 1 ATOM 97 C CB . ASP A 1 42 ? 24.178 37.883 -3.892 1.00 12.25 ? 42 ASP A CB 1 ATOM 98 C CG . ASP A 1 42 ? 24.700 36.472 -3.795 1.00 15.42 ? 42 ASP A CG 1 ATOM 99 O OD1 . ASP A 1 42 ? 24.059 35.580 -4.377 1.00 19.82 ? 42 ASP A OD1 1 ATOM 100 O OD2 . ASP A 1 42 ? 25.741 36.240 -3.166 1.00 15.41 ? 42 ASP A OD2 1 ATOM 101 N N . VAL A 1 43 ? 24.044 40.735 -5.317 1.00 10.27 ? 43 VAL A N 1 ATOM 102 C CA . VAL A 1 43 ? 23.498 42.094 -5.319 1.00 10.14 ? 43 VAL A CA 1 ATOM 103 C C . VAL A 1 43 ? 24.258 42.849 -6.399 1.00 9.56 ? 43 VAL A C 1 ATOM 104 O O . VAL A 1 43 ? 25.496 42.965 -6.330 1.00 10.01 ? 43 VAL A O 1 ATOM 105 C CB . VAL A 1 43 ? 23.692 42.796 -3.971 1.00 10.26 ? 43 VAL A CB 1 ATOM 106 C CG1 . VAL A 1 43 ? 23.124 44.211 -4.059 1.00 12.18 ? 43 VAL A CG1 1 ATOM 107 C CG2 . VAL A 1 43 ? 23.017 41.993 -2.837 1.00 12.41 ? 43 VAL A CG2 1 ATOM 108 N N . GLN A 1 44 ? 23.545 43.374 -7.394 1.00 9.31 ? 44 GLN A N 1 ATOM 109 C CA . GLN A 1 44 ? 24.173 44.215 -8.402 1.00 9.83 ? 44 GLN A CA 1 ATOM 110 C C . GLN A 1 44 ? 23.456 45.542 -8.298 1.00 8.75 ? 44 GLN A C 1 ATOM 111 O O . GLN A 1 44 ? 22.250 45.610 -8.420 1.00 9.19 ? 44 GLN A O 1 ATOM 112 C CB . GLN A 1 44 ? 24.001 43.579 -9.780 1.00 9.80 ? 44 GLN A CB 1 ATOM 113 C CG . GLN A 1 44 ? 25.084 43.991 -10.765 1.00 9.67 ? 44 GLN A CG 1 ATOM 114 C CD . GLN A 1 44 ? 25.163 45.504 -10.938 1.00 9.62 ? 44 GLN A CD 1 ATOM 115 O OE1 . GLN A 1 44 ? 24.156 46.145 -11.261 1.00 9.66 ? 44 GLN A OE1 1 ATOM 116 N NE2 . GLN A 1 44 ? 26.349 46.085 -10.646 1.00 8.95 ? 44 GLN A NE2 1 ATOM 117 N N . MET A 1 45 ? 24.189 46.605 -7.964 1.00 8.86 ? 45 MET A N 1 ATOM 118 C CA . MET A 1 45 ? 23.517 47.811 -7.509 1.00 8.91 ? 45 MET A CA 1 ATOM 119 C C . MET A 1 45 ? 22.599 48.470 -8.554 1.00 8.30 ? 45 MET A C 1 ATOM 120 O O . MET A 1 45 ? 21.617 49.089 -8.182 1.00 9.34 ? 45 MET A O 1 ATOM 121 C CB . MET A 1 45 ? 24.524 48.823 -6.930 1.00 8.77 ? 45 MET A CB 1 ATOM 122 C CG . MET A 1 45 ? 25.162 48.349 -5.634 1.00 9.54 ? 45 MET A CG 1 ATOM 123 S SD . MET A 1 45 ? 23.917 48.093 -4.315 1.00 11.37 ? 45 MET A SD 1 ATOM 124 C CE . MET A 1 45 ? 23.201 49.747 -4.164 1.00 13.86 ? 45 MET A CE 1 ATOM 125 N N . LEU A 1 46 ? 22.973 48.380 -9.818 1.00 8.60 ? 46 LEU A N 1 ATOM 126 C CA . LEU A 1 46 ? 22.091 48.959 -10.873 1.00 9.35 ? 46 LEU A CA 1 ATOM 127 C C . LEU A 1 46 ? 20.749 48.184 -10.907 1.00 10.32 ? 46 LEU A C 1 ATOM 128 O O . LEU A 1 46 ? 19.676 48.770 -11.001 1.00 10.54 ? 46 LEU A O 1 ATOM 129 C CB . LEU A 1 46 ? 22.770 48.898 -12.210 1.00 10.38 ? 46 LEU A CB 1 ATOM 130 C CG . LEU A 1 46 ? 22.010 49.669 -13.310 1.00 10.64 ? 46 LEU A CG 1 ATOM 131 C CD1 . LEU A 1 46 ? 22.040 51.205 -13.079 1.00 10.80 ? 46 LEU A CD1 1 ATOM 132 C CD2 . LEU A 1 46 ? 22.574 49.310 -14.634 1.00 12.87 ? 46 LEU A CD2 1 ATOM 133 N N . GLU A 1 47 ? 20.841 46.866 -10.784 1.00 10.17 ? 47 GLU A N 1 ATOM 134 C CA . GLU A 1 47 ? 19.636 46.014 -10.798 1.00 11.81 ? 47 GLU A CA 1 ATOM 135 C C . GLU A 1 47 ? 18.835 46.307 -9.549 1.00 11.70 ? 47 GLU A C 1 ATOM 136 O O . GLU A 1 47 ? 17.603 46.439 -9.585 1.00 12.45 ? 47 GLU A O 1 ATOM 137 C CB . GLU A 1 47 ? 20.052 44.547 -10.877 1.00 12.73 ? 47 GLU A CB 1 ATOM 138 C CG . GLU A 1 47 ? 18.916 43.564 -11.140 1.00 16.57 ? 47 GLU A CG 1 ATOM 139 C CD . GLU A 1 47 ? 18.126 43.207 -9.909 1.00 21.40 ? 47 GLU A CD 1 ATOM 140 O OE1 . GLU A 1 47 ? 18.608 43.353 -8.750 1.00 20.00 ? 47 GLU A OE1 1 ATOM 141 O OE2 . GLU A 1 47 ? 16.967 42.757 -10.100 1.00 24.00 ? 47 GLU A OE2 1 ATOM 142 N N . LEU A 1 48 ? 19.504 46.453 -8.414 1.00 11.15 ? 48 LEU A N 1 ATOM 143 C CA . LEU A 1 48 ? 18.809 46.778 -7.189 1.00 12.18 ? 48 LEU A CA 1 ATOM 144 C C . LEU A 1 48 ? 18.062 48.099 -7.295 1.00 11.56 ? 48 LEU A C 1 ATOM 145 O O . LEU A 1 48 ? 16.896 48.215 -6.909 1.00 12.47 ? 48 LEU A O 1 ATOM 146 C CB . LEU A 1 48 ? 19.793 46.845 -6.011 1.00 12.31 ? 48 LEU A CB 1 ATOM 147 C CG . LEU A 1 48 ? 19.122 46.979 -4.658 1.00 13.49 ? 48 LEU A CG 1 ATOM 148 C CD1 . LEU A 1 48 ? 18.129 45.833 -4.404 1.00 20.88 ? 48 LEU A CD1 1 ATOM 149 C CD2 . LEU A 1 48 ? 20.138 47.101 -3.505 1.00 16.39 ? 48 LEU A CD2 1 ATOM 150 N N . TYR A 1 49 ? 18.732 49.127 -7.817 1.00 10.57 ? 49 TYR A N 1 ATOM 151 C CA . TYR A 1 49 ? 18.109 50.431 -8.056 1.00 10.74 ? 49 TYR A CA 1 ATOM 152 C C . TYR A 1 49 ? 16.850 50.330 -8.947 1.00 11.74 ? 49 TYR A C 1 ATOM 153 O O . TYR A 1 49 ? 15.866 51.003 -8.686 1.00 12.19 ? 49 TYR A O 1 ATOM 154 C CB . TYR A 1 49 ? 19.149 51.399 -8.659 1.00 10.09 ? 49 TYR A CB 1 ATOM 155 C CG . TYR A 1 49 ? 19.684 52.327 -7.600 1.00 10.37 ? 49 TYR A CG 1 ATOM 156 C CD1 . TYR A 1 49 ? 20.161 51.848 -6.374 1.00 10.14 ? 49 TYR A CD1 1 ATOM 157 C CD2 . TYR A 1 49 ? 19.696 53.699 -7.820 1.00 10.91 ? 49 TYR A CD2 1 ATOM 158 C CE1 . TYR A 1 49 ? 20.595 52.708 -5.393 1.00 9.80 ? 49 TYR A CE1 1 ATOM 159 C CE2 . TYR A 1 49 ? 20.158 54.580 -6.850 1.00 9.77 ? 49 TYR A CE2 1 ATOM 160 C CZ . TYR A 1 49 ? 20.588 54.069 -5.622 1.00 8.46 ? 49 TYR A CZ 1 ATOM 161 O OH . TYR A 1 49 ? 20.985 54.885 -4.613 1.00 10.38 ? 49 TYR A OH 1 ATOM 162 N N . ASP A 1 50 ? 16.888 49.484 -9.958 1.00 12.11 ? 50 ASP A N 1 ATOM 163 C CA . ASP A 1 50 ? 15.761 49.374 -10.890 1.00 14.63 ? 50 ASP A CA 1 ATOM 164 C C . ASP A 1 50 ? 14.533 48.801 -10.146 1.00 15.58 ? 50 ASP A C 1 ATOM 165 O O . ASP A 1 50 ? 13.390 49.215 -10.437 1.00 16.49 ? 50 ASP A O 1 ATOM 166 C CB . ASP A 1 50 ? 16.208 48.517 -12.067 1.00 15.78 ? 50 ASP A CB 1 ATOM 167 C CG . ASP A 1 50 ? 15.371 48.713 -13.308 1.00 20.17 ? 50 ASP A CG 1 ATOM 168 O OD1 . ASP A 1 50 ? 14.661 49.735 -13.419 1.00 24.39 ? 50 ASP A OD1 1 ATOM 169 O OD2 . ASP A 1 50 ? 15.436 47.888 -14.250 1.00 25.55 ? 50 ASP A OD2 1 ATOM 170 N N . ARG A 1 51 ? 14.771 47.893 -9.198 1.00 15.66 ? 51 ARG A N 1 ATOM 171 C CA . ARG A 1 51 ? 13.717 47.195 -8.423 1.00 18.77 ? 51 ARG A CA 1 ATOM 172 C C . ARG A 1 51 ? 13.195 47.959 -7.224 1.00 17.76 ? 51 ARG A C 1 ATOM 173 O O . ARG A 1 51 ? 12.024 47.828 -6.878 1.00 19.39 ? 51 ARG A O 1 ATOM 174 C CB . ARG A 1 51 ? 14.249 45.854 -7.866 1.00 19.10 ? 51 ARG A CB 1 ATOM 175 C CG . ARG A 1 51 ? 14.394 44.746 -8.840 1.00 23.52 ? 51 ARG A CG 1 ATOM 176 C CD . ARG A 1 51 ? 15.015 43.475 -8.217 1.00 24.34 ? 51 ARG A CD 1 ATOM 177 N NE . ARG A 1 51 ? 14.930 43.462 -6.761 1.00 31.45 ? 51 ARG A NE 1 ATOM 178 C CZ . ARG A 1 51 ? 15.960 43.289 -5.945 1.00 33.89 ? 51 ARG A CZ 1 ATOM 179 N NH1 . ARG A 1 51 ? 17.183 43.081 -6.431 1.00 34.76 ? 51 ARG A NH1 1 ATOM 180 N NH2 . ARG A 1 51 ? 15.762 43.312 -4.631 1.00 36.47 ? 51 ARG A NH2 1 ATOM 181 N N . MET A 1 52 ? 14.052 48.719 -6.530 1.00 16.10 ? 52 MET A N 1 ATOM 182 C CA A MET A 1 52 ? 13.659 49.383 -5.286 0.50 16.60 ? 52 MET A CA 1 ATOM 183 C CA B MET A 1 52 ? 13.676 49.403 -5.287 0.50 15.90 ? 52 MET A CA 1 ATOM 184 C C . MET A 1 52 ? 12.643 50.502 -5.462 1.00 15.79 ? 52 MET A C 1 ATOM 185 O O . MET A 1 52 ? 12.660 51.208 -6.454 1.00 15.96 ? 52 MET A O 1 ATOM 186 C CB A MET A 1 52 ? 14.890 49.978 -4.603 0.50 16.49 ? 52 MET A CB 1 ATOM 187 C CB B MET A 1 52 ? 14.904 50.076 -4.677 0.50 15.73 ? 52 MET A CB 1 ATOM 188 C CG A MET A 1 52 ? 15.756 48.970 -3.876 0.50 16.95 ? 52 MET A CG 1 ATOM 189 C CG B MET A 1 52 ? 15.939 49.148 -4.090 0.50 15.27 ? 52 MET A CG 1 ATOM 190 S SD A MET A 1 52 ? 17.279 49.732 -3.257 0.50 17.87 ? 52 MET A SD 1 ATOM 191 S SD B MET A 1 52 ? 17.487 50.059 -3.773 0.50 14.98 ? 52 MET A SD 1 ATOM 192 C CE A MET A 1 52 ? 16.635 50.961 -2.193 0.50 18.99 ? 52 MET A CE 1 ATOM 193 C CE B MET A 1 52 ? 16.977 51.298 -2.618 0.50 13.96 ? 52 MET A CE 1 ATOM 194 N N . SER A 1 53 ? 11.776 50.684 -4.458 1.00 15.96 ? 53 SER A N 1 ATOM 195 C CA A SER A 1 53 ? 10.741 51.711 -4.493 0.50 16.98 ? 53 SER A CA 1 ATOM 196 C CA B SER A 1 53 ? 10.750 51.729 -4.525 0.50 16.92 ? 53 SER A CA 1 ATOM 197 C C . SER A 1 53 ? 11.174 53.074 -3.914 1.00 16.69 ? 53 SER A C 1 ATOM 198 O O . SER A 1 53 ? 10.557 54.102 -4.176 1.00 17.63 ? 53 SER A O 1 ATOM 199 C CB A SER A 1 53 ? 9.492 51.176 -3.772 0.50 16.99 ? 53 SER A CB 1 ATOM 200 C CB B SER A 1 53 ? 9.432 51.255 -3.884 0.50 17.13 ? 53 SER A CB 1 ATOM 201 O OG A SER A 1 53 ? 9.005 50.029 -4.463 0.50 19.55 ? 53 SER A OG 1 ATOM 202 O OG B SER A 1 53 ? 9.518 51.210 -2.481 0.50 18.84 ? 53 SER A OG 1 ATOM 203 N N . PHE A 1 54 ? 12.196 53.061 -3.067 1.00 15.57 ? 54 PHE A N 1 ATOM 204 C CA . PHE A 1 54 ? 12.733 54.283 -2.448 1.00 14.79 ? 54 PHE A CA 1 ATOM 205 C C . PHE A 1 54 ? 11.697 55.069 -1.640 1.00 15.83 ? 54 PHE A C 1 ATOM 206 O O . PHE A 1 54 ? 11.797 56.287 -1.497 1.00 16.10 ? 54 PHE A O 1 ATOM 207 C CB . PHE A 1 54 ? 13.398 55.223 -3.496 1.00 14.32 ? 54 PHE A CB 1 ATOM 208 C CG . PHE A 1 54 ? 14.666 54.665 -4.125 1.00 12.50 ? 54 PHE A CG 1 ATOM 209 C CD1 . PHE A 1 54 ? 14.607 53.833 -5.229 1.00 13.50 ? 54 PHE A CD1 1 ATOM 210 C CD2 . PHE A 1 54 ? 15.918 55.015 -3.608 1.00 12.78 ? 54 PHE A CD2 1 ATOM 211 C CE1 . PHE A 1 54 ? 15.765 53.316 -5.816 1.00 12.43 ? 54 PHE A CE1 1 ATOM 212 C CE2 . PHE A 1 54 ? 17.068 54.554 -4.193 1.00 13.64 ? 54 PHE A CE2 1 ATOM 213 C CZ . PHE A 1 54 ? 17.010 53.691 -5.295 1.00 13.50 ? 54 PHE A CZ 1 ATOM 214 N N . LYS A 1 55 ? 10.708 54.383 -1.066 1.00 16.30 ? 55 LYS A N 1 ATOM 215 C CA . LYS A 1 55 ? 9.744 55.123 -0.243 1.00 17.54 ? 55 LYS A CA 1 ATOM 216 C C . LYS A 1 55 ? 10.343 55.593 1.063 1.00 17.89 ? 55 LYS A C 1 ATOM 217 O O . LYS A 1 55 ? 11.061 54.873 1.733 1.00 19.73 ? 55 LYS A O 1 ATOM 218 C CB . LYS A 1 55 ? 8.481 54.296 0.052 1.00 17.82 ? 55 LYS A CB 1 ATOM 219 C CG . LYS A 1 55 ? 7.732 53.813 -1.174 1.00 18.98 ? 55 LYS A CG 1 ATOM 220 C CD . LYS A 1 55 ? 7.442 54.920 -2.178 1.00 19.73 ? 55 LYS A CD 1 ATOM 221 C CE . LYS A 1 55 ? 6.587 54.419 -3.349 1.00 23.74 ? 55 LYS A CE 1 ATOM 222 N NZ . LYS A 1 55 ? 6.298 55.513 -4.336 1.00 24.53 ? 55 LYS A NZ 1 ATOM 223 N N . ASP A 1 56 ? 10.025 56.813 1.440 1.00 17.48 ? 56 ASP A N 1 ATOM 224 C CA . ASP A 1 56 ? 10.590 57.420 2.616 1.00 18.42 ? 56 ASP A CA 1 ATOM 225 C C . ASP A 1 56 ? 9.535 57.433 3.729 1.00 19.61 ? 56 ASP A C 1 ATOM 226 O O . ASP A 1 56 ? 8.921 58.464 4.022 1.00 21.07 ? 56 ASP A O 1 ATOM 227 C CB . ASP A 1 56 ? 11.117 58.820 2.257 1.00 17.84 ? 56 ASP A CB 1 ATOM 228 C CG . ASP A 1 56 ? 11.725 59.543 3.436 1.00 17.38 ? 56 ASP A CG 1 ATOM 229 O OD1 . ASP A 1 56 ? 12.234 58.882 4.366 1.00 16.87 ? 56 ASP A OD1 1 ATOM 230 O OD2 . ASP A 1 56 ? 11.717 60.789 3.521 1.00 20.01 ? 56 ASP A OD2 1 ATOM 231 N N . ILE A 1 57 ? 9.348 56.285 4.364 1.00 20.01 ? 57 ILE A N 1 ATOM 232 C CA . ILE A 1 57 ? 8.309 56.179 5.383 1.00 21.45 ? 57 ILE A CA 1 ATOM 233 C C . ILE A 1 57 ? 8.912 56.208 6.776 1.00 21.50 ? 57 ILE A C 1 ATOM 234 O O . ILE A 1 57 ? 10.067 55.775 6.986 1.00 21.08 ? 57 ILE A O 1 ATOM 235 C CB . ILE A 1 57 ? 7.396 54.941 5.155 1.00 22.86 ? 57 ILE A CB 1 ATOM 236 C CG1 . ILE A 1 57 ? 8.165 53.637 5.303 1.00 23.92 ? 57 ILE A CG1 1 ATOM 237 C CG2 . ILE A 1 57 ? 6.691 55.023 3.771 1.00 23.22 ? 57 ILE A CG2 1 ATOM 238 C CD1 . ILE A 1 57 ? 7.310 52.464 5.800 1.00 27.80 ? 57 ILE A CD1 1 ATOM 239 N N . ASP A 1 58 ? 8.137 56.734 7.722 1.00 20.83 ? 58 ASP A N 1 ATOM 240 C CA . ASP A 1 58 ? 8.524 56.767 9.127 1.00 21.39 ? 58 ASP A CA 1 ATOM 241 C C . ASP A 1 58 ? 8.538 55.342 9.676 1.00 20.60 ? 58 ASP A C 1 ATOM 242 O O . ASP A 1 58 ? 7.485 54.721 9.862 1.00 20.74 ? 58 ASP A O 1 ATOM 243 C CB . ASP A 1 58 ? 7.544 57.664 9.900 1.00 21.99 ? 58 ASP A CB 1 ATOM 244 C CG . ASP A 1 58 ? 7.950 57.892 11.338 1.00 25.54 ? 58 ASP A CG 1 ATOM 245 O OD1 . ASP A 1 58 ? 8.820 57.168 11.878 1.00 24.35 ? 58 ASP A OD1 1 ATOM 246 O OD2 . ASP A 1 58 ? 7.434 58.810 12.017 1.00 28.97 ? 58 ASP A OD2 1 ATOM 247 N N . GLY A 1 59 ? 9.728 54.804 9.914 1.00 19.40 ? 59 GLY A N 1 ATOM 248 C CA . GLY A 1 59 ? 9.844 53.456 10.422 1.00 17.93 ? 59 GLY A CA 1 ATOM 249 C C . GLY A 1 59 ? 9.769 53.341 11.943 1.00 16.40 ? 59 GLY A C 1 ATOM 250 O O . GLY A 1 59 ? 9.996 52.254 12.469 1.00 16.92 ? 59 GLY A O 1 ATOM 251 N N . GLY A 1 60 ? 9.505 54.445 12.640 1.00 16.23 ? 60 GLY A N 1 ATOM 252 C CA . GLY A 1 60 ? 9.510 54.432 14.091 1.00 17.34 ? 60 GLY A CA 1 ATOM 253 C C . GLY A 1 60 ? 10.787 55.026 14.692 1.00 16.21 ? 60 GLY A C 1 ATOM 254 O O . GLY A 1 60 ? 11.326 56.019 14.172 1.00 16.89 ? 60 GLY A O 1 ATOM 255 N N . VAL A 1 61 ? 11.248 54.485 15.818 1.00 15.74 ? 61 VAL A N 1 ATOM 256 C CA . VAL A 1 61 ? 12.483 55.001 16.432 1.00 14.57 ? 61 VAL A CA 1 ATOM 257 C C . VAL A 1 61 ? 13.660 54.917 15.435 1.00 13.96 ? 61 VAL A C 1 ATOM 258 O O . VAL A 1 61 ? 14.472 55.850 15.354 1.00 14.35 ? 61 VAL A O 1 ATOM 259 C CB . VAL A 1 61 ? 12.821 54.357 17.806 1.00 15.57 ? 61 VAL A CB 1 ATOM 260 C CG1 . VAL A 1 61 ? 11.749 54.712 18.843 1.00 16.13 ? 61 VAL A CG1 1 ATOM 261 C CG2 . VAL A 1 61 ? 13.028 52.849 17.714 1.00 16.13 ? 61 VAL A CG2 1 ATOM 262 N N . TRP A 1 62 ? 13.719 53.839 14.673 1.00 13.47 ? 62 TRP A N 1 ATOM 263 C CA . TRP A 1 62 ? 14.645 53.768 13.543 1.00 12.92 ? 62 TRP A CA 1 ATOM 264 C C . TRP A 1 62 ? 13.905 54.413 12.396 1.00 13.51 ? 62 TRP A C 1 ATOM 265 O O . TRP A 1 62 ? 13.124 53.758 11.690 1.00 13.32 ? 62 TRP A O 1 ATOM 266 C CB . TRP A 1 62 ? 15.057 52.320 13.242 1.00 12.84 ? 62 TRP A CB 1 ATOM 267 C CG . TRP A 1 62 ? 16.032 52.213 12.097 1.00 11.27 ? 62 TRP A CG 1 ATOM 268 C CD1 . TRP A 1 62 ? 16.718 53.259 11.478 1.00 11.65 ? 62 TRP A CD1 1 ATOM 269 C CD2 . TRP A 1 62 ? 16.400 51.031 11.407 1.00 11.42 ? 62 TRP A CD2 1 ATOM 270 N NE1 . TRP A 1 62 ? 17.474 52.759 10.447 1.00 11.20 ? 62 TRP A NE1 1 ATOM 271 C CE2 . TRP A 1 62 ? 17.308 51.401 10.375 1.00 12.04 ? 62 TRP A CE2 1 ATOM 272 C CE3 . TRP A 1 62 ? 16.049 49.677 11.536 1.00 10.40 ? 62 TRP A CE3 1 ATOM 273 C CZ2 . TRP A 1 62 ? 17.862 50.470 9.488 1.00 11.69 ? 62 TRP A CZ2 1 ATOM 274 C CZ3 . TRP A 1 62 ? 16.591 48.753 10.674 1.00 12.05 ? 62 TRP A CZ3 1 ATOM 275 C CH2 . TRP A 1 62 ? 17.502 49.143 9.655 1.00 11.57 ? 62 TRP A CH2 1 ATOM 276 N N . LYS A 1 63 ? 14.129 55.717 12.206 1.00 13.01 ? 63 LYS A N 1 ATOM 277 C CA . LYS A 1 63 ? 13.224 56.499 11.341 1.00 14.58 ? 63 LYS A CA 1 ATOM 278 C C . LYS A 1 63 ? 13.198 56.012 9.911 1.00 14.61 ? 63 LYS A C 1 ATOM 279 O O . LYS A 1 63 ? 12.170 56.101 9.225 1.00 15.37 ? 63 LYS A O 1 ATOM 280 C CB . LYS A 1 63 ? 13.560 57.992 11.388 1.00 14.85 ? 63 LYS A CB 1 ATOM 281 C CG . LYS A 1 63 ? 13.181 58.683 12.707 1.00 19.66 ? 63 LYS A CG 1 ATOM 282 C CD . LYS A 1 63 ? 11.688 59.065 12.741 1.00 23.24 ? 63 LYS A CD 1 ATOM 283 C CE . LYS A 1 63 ? 11.282 59.766 14.049 1.00 24.92 ? 63 LYS A CE 1 ATOM 284 N NZ . LYS A 1 63 ? 11.383 58.903 15.302 1.00 29.01 ? 63 LYS A NZ 1 ATOM 285 N N . GLN A 1 64 ? 14.321 55.486 9.434 1.00 12.84 ? 64 GLN A N 1 ATOM 286 C CA . GLN A 1 64 ? 14.398 55.033 8.060 1.00 12.48 ? 64 GLN A CA 1 ATOM 287 C C . GLN A 1 64 ? 14.467 53.522 7.913 1.00 12.20 ? 64 GLN A C 1 ATOM 288 O O . GLN A 1 64 ? 14.778 52.995 6.841 1.00 11.89 ? 64 GLN A O 1 ATOM 289 C CB . GLN A 1 64 ? 15.596 55.698 7.354 1.00 12.13 ? 64 GLN A CB 1 ATOM 290 C CG . GLN A 1 64 ? 15.511 57.194 7.388 1.00 12.61 ? 64 GLN A CG 1 ATOM 291 C CD . GLN A 1 64 ? 16.876 57.881 7.244 1.00 11.77 ? 64 GLN A CD 1 ATOM 292 O OE1 . GLN A 1 64 ? 17.837 57.536 7.967 1.00 12.32 ? 64 GLN A OE1 1 ATOM 293 N NE2 . GLN A 1 64 ? 16.940 58.866 6.367 1.00 12.02 ? 64 GLN A NE2 1 ATOM 294 N N . GLY A 1 65 ? 14.111 52.823 9.001 1.00 13.10 ? 65 GLY A N 1 ATOM 295 C CA . GLY A 1 65 ? 14.073 51.368 8.997 1.00 13.06 ? 65 GLY A CA 1 ATOM 296 C C . GLY A 1 65 ? 12.711 50.817 9.420 1.00 13.78 ? 65 GLY A C 1 ATOM 297 O O . GLY A 1 65 ? 11.679 51.196 8.839 1.00 14.94 ? 65 GLY A O 1 ATOM 298 N N . TRP A 1 66 ? 12.733 49.926 10.400 1.00 14.35 ? 66 TRP A N 1 ATOM 299 C CA . TRP A 1 66 ? 11.496 49.298 10.917 1.00 14.40 ? 66 TRP A CA 1 ATOM 300 C C . TRP A 1 66 ? 11.782 48.944 12.354 1.00 15.07 ? 66 TRP A C 1 ATOM 301 O O . TRP A 1 66 ? 12.915 49.079 12.828 1.00 14.47 ? 66 TRP A O 1 ATOM 302 C CB . TRP A 1 66 ? 11.118 48.066 10.086 1.00 15.00 ? 66 TRP A CB 1 ATOM 303 C CG . TRP A 1 66 ? 12.066 46.907 10.233 1.00 14.62 ? 66 TRP A CG 1 ATOM 304 C CD1 . TRP A 1 66 ? 11.954 45.858 11.110 1.00 14.41 ? 66 TRP A CD1 1 ATOM 305 C CD2 . TRP A 1 66 ? 13.292 46.688 9.518 1.00 13.89 ? 66 TRP A CD2 1 ATOM 306 N NE1 . TRP A 1 66 ? 13.021 45.003 10.991 1.00 15.67 ? 66 TRP A NE1 1 ATOM 307 C CE2 . TRP A 1 66 ? 13.855 45.481 10.005 1.00 13.28 ? 66 TRP A CE2 1 ATOM 308 C CE3 . TRP A 1 66 ? 13.968 47.375 8.483 1.00 14.49 ? 66 TRP A CE3 1 ATOM 309 C CZ2 . TRP A 1 66 ? 15.056 44.942 9.503 1.00 16.01 ? 66 TRP A CZ2 1 ATOM 310 C CZ3 . TRP A 1 66 ? 15.161 46.834 7.987 1.00 14.52 ? 66 TRP A CZ3 1 ATOM 311 C CH2 . TRP A 1 66 ? 15.703 45.643 8.512 1.00 14.54 ? 66 TRP A CH2 1 ATOM 312 N N . ASN A 1 67 ? 10.745 48.512 13.091 1.00 15.59 ? 67 ASN A N 1 ATOM 313 C CA . ASN A 1 67 ? 10.923 48.075 14.478 1.00 15.64 ? 67 ASN A CA 1 ATOM 314 C C . ASN A 1 67 ? 11.507 46.670 14.505 1.00 15.77 ? 67 ASN A C 1 ATOM 315 O O . ASN A 1 67 ? 10.806 45.677 14.242 1.00 15.93 ? 67 ASN A O 1 ATOM 316 C CB . ASN A 1 67 ? 9.569 48.040 15.226 1.00 17.01 ? 67 ASN A CB 1 ATOM 317 C CG . ASN A 1 67 ? 8.982 49.404 15.479 1.00 19.85 ? 67 ASN A CG 1 ATOM 318 O OD1 . ASN A 1 67 ? 9.672 50.432 15.554 1.00 21.92 ? 67 ASN A OD1 1 ATOM 319 N ND2 . ASN A 1 67 ? 7.658 49.420 15.666 1.00 23.62 ? 67 ASN A ND2 1 ATOM 320 N N . ILE A 1 68 ? 12.791 46.570 14.821 1.00 14.86 ? 68 ILE A N 1 ATOM 321 C CA . ILE A 1 68 ? 13.489 45.312 14.780 1.00 14.78 ? 68 ILE A CA 1 ATOM 322 C C . ILE A 1 68 ? 13.038 44.444 15.954 1.00 15.73 ? 68 ILE A C 1 ATOM 323 O O . ILE A 1 68 ? 12.979 44.896 17.095 1.00 16.11 ? 68 ILE A O 1 ATOM 324 C CB . ILE A 1 68 ? 15.046 45.521 14.851 1.00 14.88 ? 68 ILE A CB 1 ATOM 325 C CG1 . ILE A 1 68 ? 15.560 46.390 13.683 1.00 14.42 ? 68 ILE A CG1 1 ATOM 326 C CG2 . ILE A 1 68 ? 15.767 44.182 14.896 1.00 16.02 ? 68 ILE A CG2 1 ATOM 327 C CD1 . ILE A 1 68 ? 17.028 46.903 13.879 1.00 13.28 ? 68 ILE A CD1 1 ATOM 328 N N . LYS A 1 69 ? 12.789 43.183 15.628 1.00 17.25 ? 69 LYS A N 1 ATOM 329 C CA . LYS A 1 69 ? 12.448 42.166 16.634 1.00 19.20 ? 69 LYS A CA 1 ATOM 330 C C . LYS A 1 69 ? 13.497 41.076 16.628 1.00 18.57 ? 69 LYS A C 1 ATOM 331 O O . LYS A 1 69 ? 14.050 40.764 15.589 1.00 18.27 ? 69 LYS A O 1 ATOM 332 C CB . LYS A 1 69 ? 11.063 41.591 16.327 1.00 19.99 ? 69 LYS A CB 1 ATOM 333 C CG . LYS A 1 69 ? 9.935 42.604 16.592 1.00 23.06 ? 69 LYS A CG 1 ATOM 334 C CD . LYS A 1 69 ? 8.610 42.254 15.875 1.00 24.60 ? 69 LYS A CD 1 ATOM 335 C CE . LYS A 1 69 ? 8.058 40.856 16.244 1.00 30.14 ? 69 LYS A CE 1 ATOM 336 N NZ . LYS A 1 69 ? 6.924 40.426 15.359 1.00 30.15 ? 69 LYS A NZ 1 ATOM 337 N N . TYR A 1 70 ? 13.791 40.508 17.796 1.00 18.52 ? 70 TYR A N 1 ATOM 338 C CA . TYR A 1 70 ? 14.698 39.358 17.853 1.00 19.13 ? 70 TYR A CA 1 ATOM 339 C C . TYR A 1 70 ? 14.125 38.300 18.775 1.00 20.92 ? 70 TYR A C 1 ATOM 340 O O . TYR A 1 70 ? 13.343 38.620 19.669 1.00 20.98 ? 70 TYR A O 1 ATOM 341 C CB . TYR A 1 70 ? 16.108 39.775 18.315 1.00 18.82 ? 70 TYR A CB 1 ATOM 342 C CG . TYR A 1 70 ? 16.164 40.412 19.676 1.00 17.84 ? 70 TYR A CG 1 ATOM 343 C CD1 . TYR A 1 70 ? 15.929 41.766 19.835 1.00 17.70 ? 70 TYR A CD1 1 ATOM 344 C CD2 . TYR A 1 70 ? 16.434 39.650 20.820 1.00 18.80 ? 70 TYR A CD2 1 ATOM 345 C CE1 . TYR A 1 70 ? 15.967 42.370 21.074 1.00 19.09 ? 70 TYR A CE1 1 ATOM 346 C CE2 . TYR A 1 70 ? 16.483 40.240 22.072 1.00 20.06 ? 70 TYR A CE2 1 ATOM 347 C CZ . TYR A 1 70 ? 16.247 41.600 22.198 1.00 19.23 ? 70 TYR A CZ 1 ATOM 348 O OH . TYR A 1 70 ? 16.273 42.212 23.442 1.00 20.57 ? 70 TYR A OH 1 ATOM 349 N N . ASP A 1 71 ? 14.528 37.060 18.535 1.00 22.82 ? 71 ASP A N 1 ATOM 350 C CA . ASP A 1 71 ? 14.173 35.940 19.398 1.00 24.38 ? 71 ASP A CA 1 ATOM 351 C C . ASP A 1 71 ? 15.161 35.914 20.555 1.00 24.99 ? 71 ASP A C 1 ATOM 352 O O . ASP A 1 71 ? 16.346 35.634 20.343 1.00 24.26 ? 71 ASP A O 1 ATOM 353 C CB . ASP A 1 71 ? 14.243 34.640 18.606 1.00 25.30 ? 71 ASP A CB 1 ATOM 354 C CG . ASP A 1 71 ? 13.815 33.417 19.429 1.00 27.75 ? 71 ASP A CG 1 ATOM 355 O OD1 . ASP A 1 71 ? 13.656 33.514 20.667 1.00 29.97 ? 71 ASP A OD1 1 ATOM 356 O OD2 . ASP A 1 71 ? 13.632 32.309 18.901 1.00 31.74 ? 71 ASP A OD2 1 ATOM 357 N N . PRO A 1 72 ? 14.699 36.190 21.781 1.00 25.83 ? 72 PRO A N 1 ATOM 358 C CA . PRO A 1 72 ? 15.617 36.216 22.927 1.00 26.14 ? 72 PRO A CA 1 ATOM 359 C C . PRO A 1 72 ? 16.359 34.885 23.118 1.00 26.07 ? 72 PRO A C 1 ATOM 360 O O . PRO A 1 72 ? 17.441 34.878 23.704 1.00 27.16 ? 72 PRO A O 1 ATOM 361 C CB . PRO A 1 72 ? 14.706 36.545 24.118 1.00 26.33 ? 72 PRO A CB 1 ATOM 362 C CG . PRO A 1 72 ? 13.339 36.202 23.656 1.00 27.41 ? 72 PRO A CG 1 ATOM 363 C CD . PRO A 1 72 ? 13.312 36.486 22.187 1.00 26.12 ? 72 PRO A CD 1 ATOM 364 N N . LEU A 1 73 ? 15.814 33.795 22.580 1.00 26.30 ? 73 LEU A N 1 ATOM 365 C CA . LEU A 1 73 ? 16.436 32.475 22.687 1.00 26.46 ? 73 LEU A CA 1 ATOM 366 C C . LEU A 1 73 ? 17.510 32.183 21.629 1.00 25.73 ? 73 LEU A C 1 ATOM 367 O O . LEU A 1 73 ? 18.131 31.113 21.640 1.00 25.83 ? 73 LEU A O 1 ATOM 368 C CB . LEU A 1 73 ? 15.361 31.384 22.644 1.00 27.08 ? 73 LEU A CB 1 ATOM 369 C CG . LEU A 1 73 ? 14.297 31.406 23.739 1.00 28.88 ? 73 LEU A CG 1 ATOM 370 C CD1 . LEU A 1 73 ? 13.308 30.262 23.501 1.00 30.95 ? 73 LEU A CD1 1 ATOM 371 C CD2 . LEU A 1 73 ? 14.953 31.309 25.121 1.00 30.76 ? 73 LEU A CD2 1 ATOM 372 N N . LYS A 1 74 ? 17.742 33.135 20.721 1.00 24.79 ? 74 LYS A N 1 ATOM 373 C CA . LYS A 1 74 ? 18.821 33.004 19.736 1.00 23.94 ? 74 LYS A CA 1 ATOM 374 C C . LYS A 1 74 ? 20.202 32.849 20.367 1.00 23.11 ? 74 LYS A C 1 ATOM 375 O O . LYS A 1 74 ? 21.055 32.122 19.846 1.00 23.54 ? 74 LYS A O 1 ATOM 376 C CB . LYS A 1 74 ? 18.843 34.231 18.826 1.00 23.97 ? 74 LYS A CB 1 ATOM 377 C CG . LYS A 1 74 ? 19.885 34.163 17.727 1.00 25.02 ? 74 LYS A CG 1 ATOM 378 C CD . LYS A 1 74 ? 19.683 35.347 16.789 1.00 26.74 ? 74 LYS A CD 1 ATOM 379 C CE . LYS A 1 74 ? 20.437 35.183 15.492 1.00 29.50 ? 74 LYS A CE 1 ATOM 380 N NZ . LYS A 1 74 ? 19.983 36.250 14.544 1.00 31.20 ? 74 LYS A NZ 1 ATOM 381 N N A TYR A 1 75 ? 20.460 33.584 21.449 0.50 23.37 ? 75 TYR A N 1 ATOM 382 N N B TYR A 1 75 ? 20.392 33.540 21.485 0.50 22.87 ? 75 TYR A N 1 ATOM 383 C CA A TYR A 1 75 ? 21.748 33.485 22.149 0.50 22.69 ? 75 TYR A CA 1 ATOM 384 C CA B TYR A 1 75 ? 21.625 33.461 22.247 0.50 21.85 ? 75 TYR A CA 1 ATOM 385 C C A TYR A 1 75 ? 21.578 32.783 23.502 0.50 23.11 ? 75 TYR A C 1 ATOM 386 C C B TYR A 1 75 ? 21.431 32.536 23.425 0.50 22.45 ? 75 TYR A C 1 ATOM 387 O O A TYR A 1 75 ? 20.613 33.057 24.221 0.50 23.13 ? 75 TYR A O 1 ATOM 388 O O B TYR A 1 75 ? 20.324 32.395 23.946 0.50 22.55 ? 75 TYR A O 1 ATOM 389 C CB A TYR A 1 75 ? 22.442 34.863 22.276 0.50 22.44 ? 75 TYR A CB 1 ATOM 390 C CB B TYR A 1 75 ? 22.065 34.857 22.693 0.50 20.69 ? 75 TYR A CB 1 ATOM 391 C CG A TYR A 1 75 ? 22.750 35.489 20.921 0.50 20.77 ? 75 TYR A CG 1 ATOM 392 C CG B TYR A 1 75 ? 22.103 35.769 21.507 0.50 18.54 ? 75 TYR A CG 1 ATOM 393 C CD1 A TYR A 1 75 ? 23.792 35.007 20.133 0.50 20.15 ? 75 TYR A CD1 1 ATOM 394 C CD1 B TYR A 1 75 ? 23.121 35.666 20.569 0.50 15.87 ? 75 TYR A CD1 1 ATOM 395 C CD2 A TYR A 1 75 ? 21.975 36.538 20.410 0.50 20.64 ? 75 TYR A CD2 1 ATOM 396 C CD2 B TYR A 1 75 ? 21.075 36.667 21.270 0.50 17.88 ? 75 TYR A CD2 1 ATOM 397 C CE1 A TYR A 1 75 ? 24.060 35.545 18.873 0.50 20.96 ? 75 TYR A CE1 1 ATOM 398 C CE1 B TYR A 1 75 ? 23.132 36.478 19.434 0.50 16.33 ? 75 TYR A CE1 1 ATOM 399 C CE2 A TYR A 1 75 ? 22.244 37.092 19.148 0.50 20.32 ? 75 TYR A CE2 1 ATOM 400 C CE2 B TYR A 1 75 ? 21.077 37.486 20.142 0.50 16.13 ? 75 TYR A CE2 1 ATOM 401 C CZ A TYR A 1 75 ? 23.288 36.580 18.386 0.50 20.20 ? 75 TYR A CZ 1 ATOM 402 C CZ B TYR A 1 75 ? 22.107 37.390 19.237 0.50 16.49 ? 75 TYR A CZ 1 ATOM 403 O OH A TYR A 1 75 ? 23.570 37.108 17.137 0.50 22.34 ? 75 TYR A OH 1 ATOM 404 O OH B TYR A 1 75 ? 22.099 38.193 18.133 0.50 17.36 ? 75 TYR A OH 1 ATOM 405 N N . ASN A 1 76 ? 22.515 31.878 23.807 1.00 22.88 ? 76 ASN A N 1 ATOM 406 C CA . ASN A 1 76 ? 22.515 31.023 25.010 1.00 24.08 ? 76 ASN A CA 1 ATOM 407 C C . ASN A 1 76 ? 23.967 30.768 25.438 1.00 25.01 ? 76 ASN A C 1 ATOM 408 O O . ASN A 1 76 ? 24.902 31.290 24.822 1.00 24.69 ? 76 ASN A O 1 ATOM 409 C CB . ASN A 1 76 ? 21.784 29.692 24.734 1.00 24.63 ? 76 ASN A CB 1 ATOM 410 C CG . ASN A 1 76 ? 22.359 28.951 23.552 1.00 24.52 ? 76 ASN A CG 1 ATOM 411 O OD1 . ASN A 1 76 ? 23.550 28.676 23.500 1.00 27.05 ? 76 ASN A OD1 1 ATOM 412 N ND2 . ASN A 1 76 ? 21.505 28.622 22.590 1.00 30.40 ? 76 ASN A ND2 1 ATOM 413 N N . ALA A 1 77 ? 24.176 29.956 26.480 1.00 26.29 ? 77 ALA A N 1 ATOM 414 C CA . ALA A 1 77 ? 25.530 29.706 26.987 1.00 27.32 ? 77 ALA A CA 1 ATOM 415 C C . ALA A 1 77 ? 26.492 29.211 25.907 1.00 27.69 ? 77 ALA A C 1 ATOM 416 O O . ALA A 1 77 ? 27.691 29.490 25.960 1.00 28.54 ? 77 ALA A O 1 ATOM 417 C CB . ALA A 1 77 ? 25.490 28.715 28.152 1.00 27.70 ? 77 ALA A CB 1 ATOM 418 N N . HIS A 1 78 ? 25.965 28.499 24.917 1.00 28.44 ? 78 HIS A N 1 ATOM 419 C CA . HIS A 1 78 ? 26.817 27.879 23.896 1.00 29.09 ? 78 HIS A CA 1 ATOM 420 C C . HIS A 1 78 ? 26.971 28.738 22.654 1.00 28.14 ? 78 HIS A C 1 ATOM 421 O O . HIS A 1 78 ? 27.730 28.401 21.738 1.00 29.01 ? 78 HIS A O 1 ATOM 422 C CB . HIS A 1 78 ? 26.286 26.483 23.536 1.00 29.92 ? 78 HIS A CB 1 ATOM 423 C CG . HIS A 1 78 ? 25.942 25.654 24.735 1.00 33.35 ? 78 HIS A CG 1 ATOM 424 N ND1 . HIS A 1 78 ? 26.875 25.307 25.691 1.00 37.12 ? 78 HIS A ND1 1 ATOM 425 C CD2 . HIS A 1 78 ? 24.763 25.135 25.151 1.00 36.47 ? 78 HIS A CD2 1 ATOM 426 C CE1 . HIS A 1 78 ? 26.288 24.589 26.633 1.00 37.70 ? 78 HIS A CE1 1 ATOM 427 N NE2 . HIS A 1 78 ? 25.005 24.475 26.333 1.00 39.03 ? 78 HIS A NE2 1 ATOM 428 N N . HIS A 1 79 ? 26.247 29.847 22.628 1.00 26.26 ? 79 HIS A N 1 ATOM 429 C CA . HIS A 1 79 ? 26.235 30.721 21.468 1.00 23.55 ? 79 HIS A CA 1 ATOM 430 C C . HIS A 1 79 ? 25.947 32.140 21.943 1.00 20.33 ? 79 HIS A C 1 ATOM 431 O O . HIS A 1 79 ? 24.800 32.578 21.981 1.00 20.22 ? 79 HIS A O 1 ATOM 432 C CB . HIS A 1 79 ? 25.164 30.262 20.484 1.00 24.11 ? 79 HIS A CB 1 ATOM 433 C CG . HIS A 1 79 ? 25.144 31.046 19.207 1.00 25.42 ? 79 HIS A CG 1 ATOM 434 N ND1 . HIS A 1 79 ? 26.129 30.926 18.247 1.00 28.36 ? 79 HIS A ND1 1 ATOM 435 C CD2 . HIS A 1 79 ? 24.255 31.946 18.726 1.00 26.79 ? 79 HIS A CD2 1 ATOM 436 C CE1 . HIS A 1 79 ? 25.853 31.734 17.237 1.00 26.54 ? 79 HIS A CE1 1 ATOM 437 N NE2 . HIS A 1 79 ? 24.723 32.366 17.503 1.00 28.40 ? 79 HIS A NE2 1 ATOM 438 N N . LYS A 1 80 ? 27.006 32.820 22.355 1.00 19.08 ? 80 LYS A N 1 ATOM 439 C CA . LYS A 1 80 ? 26.867 34.151 22.908 1.00 17.51 ? 80 LYS A CA 1 ATOM 440 C C . LYS A 1 80 ? 27.056 35.214 21.823 1.00 15.79 ? 80 LYS A C 1 ATOM 441 O O . LYS A 1 80 ? 27.644 34.949 20.756 1.00 16.83 ? 80 LYS A O 1 ATOM 442 C CB . LYS A 1 80 ? 27.892 34.362 24.010 1.00 17.71 ? 80 LYS A CB 1 ATOM 443 C CG . LYS A 1 80 ? 27.778 33.308 25.118 1.00 20.26 ? 80 LYS A CG 1 ATOM 444 C CD . LYS A 1 80 ? 28.990 33.353 25.979 1.00 25.24 ? 80 LYS A CD 1 ATOM 445 C CE . LYS A 1 80 ? 29.036 34.610 26.798 1.00 25.35 ? 80 LYS A CE 1 ATOM 446 N NZ . LYS A 1 80 ? 30.008 34.411 27.933 1.00 29.28 ? 80 LYS A NZ 1 ATOM 447 N N . LEU A 1 81 ? 26.553 36.401 22.097 1.00 13.55 ? 81 LEU A N 1 ATOM 448 C CA . LEU A 1 81 ? 26.824 37.547 21.223 1.00 12.01 ? 81 LEU A CA 1 ATOM 449 C C . LEU A 1 81 ? 28.122 38.200 21.683 1.00 12.86 ? 81 LEU A C 1 ATOM 450 O O . LEU A 1 81 ? 28.228 38.604 22.844 1.00 12.45 ? 81 LEU A O 1 ATOM 451 C CB . LEU A 1 81 ? 25.662 38.511 21.326 1.00 13.05 ? 81 LEU A CB 1 ATOM 452 C CG . LEU A 1 81 ? 25.754 39.770 20.440 1.00 12.72 ? 81 LEU A CG 1 ATOM 453 C CD1 . LEU A 1 81 ? 25.743 39.386 18.945 1.00 13.39 ? 81 LEU A CD1 1 ATOM 454 C CD2 . LEU A 1 81 ? 24.643 40.747 20.760 1.00 15.89 ? 81 LEU A CD2 1 ATOM 455 N N . LYS A 1 82 ? 29.103 38.279 20.780 1.00 11.24 ? 82 LYS A N 1 ATOM 456 C CA . LYS A 1 82 ? 30.385 38.870 21.100 1.00 11.20 ? 82 LYS A CA 1 ATOM 457 C C . LYS A 1 82 ? 30.323 40.291 20.583 1.00 11.26 ? 82 LYS A C 1 ATOM 458 O O . LYS A 1 82 ? 30.082 40.501 19.384 1.00 12.73 ? 82 LYS A O 1 ATOM 459 C CB . LYS A 1 82 ? 31.516 38.110 20.404 1.00 12.47 ? 82 LYS A CB 1 ATOM 460 C CG . LYS A 1 82 ? 31.625 36.636 20.783 1.00 19.00 ? 82 LYS A CG 1 ATOM 461 C CD . LYS A 1 82 ? 31.471 36.350 22.263 1.00 28.48 ? 82 LYS A CD 1 ATOM 462 C CE . LYS A 1 82 ? 31.524 34.836 22.518 1.00 30.90 ? 82 LYS A CE 1 ATOM 463 N NZ . LYS A 1 82 ? 30.838 34.016 21.451 1.00 33.09 ? 82 LYS A NZ 1 ATOM 464 N N . VAL A 1 83 ? 30.505 41.271 21.464 1.00 9.80 ? 83 VAL A N 1 ATOM 465 C CA . VAL A 1 83 ? 30.339 42.683 21.118 1.00 10.14 ? 83 VAL A CA 1 ATOM 466 C C . VAL A 1 83 ? 31.684 43.395 21.254 1.00 10.44 ? 83 VAL A C 1 ATOM 467 O O . VAL A 1 83 ? 32.328 43.345 22.326 1.00 10.78 ? 83 VAL A O 1 ATOM 468 C CB . VAL A 1 83 ? 29.308 43.324 22.029 1.00 9.29 ? 83 VAL A CB 1 ATOM 469 C CG1 . VAL A 1 83 ? 29.123 44.821 21.702 1.00 10.82 ? 83 VAL A CG1 1 ATOM 470 C CG2 . VAL A 1 83 ? 27.951 42.604 21.915 1.00 10.78 ? 83 VAL A CG2 1 ATOM 471 N N . PHE A 1 84 ? 32.117 44.077 20.180 1.00 9.87 ? 84 PHE A N 1 ATOM 472 C CA . PHE A 1 84 ? 33.340 44.895 20.185 1.00 9.98 ? 84 PHE A CA 1 ATOM 473 C C . PHE A 1 84 ? 32.956 46.356 20.124 1.00 10.48 ? 84 PHE A C 1 ATOM 474 O O . PHE A 1 84 ? 32.405 46.831 19.116 1.00 9.74 ? 84 PHE A O 1 ATOM 475 C CB . PHE A 1 84 ? 34.205 44.514 18.984 1.00 11.01 ? 84 PHE A CB 1 ATOM 476 C CG . PHE A 1 84 ? 34.820 43.159 19.122 1.00 11.26 ? 84 PHE A CG 1 ATOM 477 C CD1 . PHE A 1 84 ? 35.905 42.974 19.975 1.00 15.08 ? 84 PHE A CD1 1 ATOM 478 C CD2 . PHE A 1 84 ? 34.319 42.065 18.437 1.00 13.46 ? 84 PHE A CD2 1 ATOM 479 C CE1 . PHE A 1 84 ? 36.501 41.713 20.147 1.00 15.28 ? 84 PHE A CE1 1 ATOM 480 C CE2 . PHE A 1 84 ? 34.904 40.791 18.602 1.00 16.85 ? 84 PHE A CE2 1 ATOM 481 C CZ . PHE A 1 84 ? 36.011 40.628 19.430 1.00 16.32 ? 84 PHE A CZ 1 ATOM 482 N N . VAL A 1 85 ? 33.231 47.066 21.210 1.00 9.15 ? 85 VAL A N 1 ATOM 483 C CA . VAL A 1 85 ? 33.005 48.486 21.277 1.00 9.21 ? 85 VAL A CA 1 ATOM 484 C C . VAL A 1 85 ? 34.311 49.149 20.888 1.00 9.11 ? 85 VAL A C 1 ATOM 485 O O . VAL A 1 85 ? 35.327 48.957 21.541 1.00 9.17 ? 85 VAL A O 1 ATOM 486 C CB . VAL A 1 85 ? 32.569 48.917 22.699 1.00 9.31 ? 85 VAL A CB 1 ATOM 487 C CG1 . VAL A 1 85 ? 32.411 50.446 22.824 1.00 11.40 ? 85 VAL A CG1 1 ATOM 488 C CG2 . VAL A 1 85 ? 31.264 48.220 23.066 1.00 10.99 ? 85 VAL A CG2 1 ATOM 489 N N . VAL A 1 86 ? 34.269 49.912 19.783 1.00 8.52 ? 86 VAL A N 1 ATOM 490 C CA . VAL A 1 86 ? 35.497 50.411 19.160 1.00 8.69 ? 86 VAL A CA 1 ATOM 491 C C . VAL A 1 86 ? 35.588 51.939 19.256 1.00 8.09 ? 86 VAL A C 1 ATOM 492 O O . VAL A 1 86 ? 34.933 52.657 18.494 1.00 8.09 ? 86 VAL A O 1 ATOM 493 C CB . VAL A 1 86 ? 35.543 49.978 17.690 1.00 8.21 ? 86 VAL A CB 1 ATOM 494 C CG1 . VAL A 1 86 ? 36.846 50.467 17.032 1.00 9.88 ? 86 VAL A CG1 1 ATOM 495 C CG2 . VAL A 1 86 ? 35.514 48.439 17.595 1.00 10.32 ? 86 VAL A CG2 1 ATOM 496 N N . PRO A 1 87 ? 36.338 52.455 20.231 1.00 7.87 ? 87 PRO A N 1 ATOM 497 C CA . PRO A 1 87 ? 36.437 53.919 20.397 1.00 8.01 ? 87 PRO A CA 1 ATOM 498 C C . PRO A 1 87 ? 37.180 54.552 19.217 1.00 7.57 ? 87 PRO A C 1 ATOM 499 O O . PRO A 1 87 ? 38.184 54.005 18.725 1.00 8.03 ? 87 PRO A O 1 ATOM 500 C CB . PRO A 1 87 ? 37.268 54.089 21.701 1.00 8.04 ? 87 PRO A CB 1 ATOM 501 C CG . PRO A 1 87 ? 37.047 52.737 22.410 1.00 10.49 ? 87 PRO A CG 1 ATOM 502 C CD . PRO A 1 87 ? 37.060 51.723 21.297 1.00 9.61 ? 87 PRO A CD 1 ATOM 503 N N . HIS A 1 88 ? 36.673 55.704 18.806 1.00 7.21 ? 88 HIS A N 1 ATOM 504 C CA . HIS A 1 88 ? 37.254 56.401 17.637 1.00 7.90 ? 88 HIS A CA 1 ATOM 505 C C . HIS A 1 88 ? 36.992 57.891 17.738 1.00 8.37 ? 88 HIS A C 1 ATOM 506 O O . HIS A 1 88 ? 36.181 58.337 18.537 1.00 8.21 ? 88 HIS A O 1 ATOM 507 C CB . HIS A 1 88 ? 36.678 55.802 16.332 1.00 8.02 ? 88 HIS A CB 1 ATOM 508 C CG . HIS A 1 88 ? 35.246 56.126 16.073 1.00 7.65 ? 88 HIS A CG 1 ATOM 509 N ND1 . HIS A 1 88 ? 34.851 57.180 15.270 1.00 7.81 ? 88 HIS A ND1 1 ATOM 510 C CD2 . HIS A 1 88 ? 34.114 55.532 16.516 1.00 7.54 ? 88 HIS A CD2 1 ATOM 511 C CE1 . HIS A 1 88 ? 33.530 57.202 15.220 1.00 8.81 ? 88 HIS A CE1 1 ATOM 512 N NE2 . HIS A 1 88 ? 33.061 56.209 15.969 1.00 9.86 ? 88 HIS A NE2 1 ATOM 513 N N . SER A 1 89 ? 37.702 58.661 16.914 1.00 8.05 ? 89 SER A N 1 ATOM 514 C CA . SER A 1 89 ? 37.601 60.095 16.910 1.00 7.98 ? 89 SER A CA 1 ATOM 515 C C . SER A 1 89 ? 37.772 60.575 15.446 1.00 7.52 ? 89 SER A C 1 ATOM 516 O O . SER A 1 89 ? 38.850 60.364 14.875 1.00 8.38 ? 89 SER A O 1 ATOM 517 C CB . SER A 1 89 ? 38.720 60.673 17.768 1.00 9.04 ? 89 SER A CB 1 ATOM 518 O OG . SER A 1 89 ? 38.710 62.074 17.717 1.00 8.59 ? 89 SER A OG 1 ATOM 519 N N . HIS A 1 90 ? 36.733 61.161 14.875 1.00 7.85 ? 90 HIS A N 1 ATOM 520 C CA . HIS A 1 90 ? 36.816 61.584 13.480 1.00 7.73 ? 90 HIS A CA 1 ATOM 521 C C . HIS A 1 90 ? 37.502 62.951 13.406 1.00 7.23 ? 90 HIS A C 1 ATOM 522 O O . HIS A 1 90 ? 36.978 63.925 13.892 1.00 8.30 ? 90 HIS A O 1 ATOM 523 C CB . HIS A 1 90 ? 35.422 61.615 12.874 1.00 8.37 ? 90 HIS A CB 1 ATOM 524 C CG . HIS A 1 90 ? 35.429 61.976 11.421 1.00 7.28 ? 90 HIS A CG 1 ATOM 525 N ND1 . HIS A 1 90 ? 35.900 61.113 10.448 1.00 7.72 ? 90 HIS A ND1 1 ATOM 526 C CD2 . HIS A 1 90 ? 35.007 63.088 10.780 1.00 9.35 ? 90 HIS A CD2 1 ATOM 527 C CE1 . HIS A 1 90 ? 35.770 61.709 9.264 1.00 7.76 ? 90 HIS A CE1 1 ATOM 528 N NE2 . HIS A 1 90 ? 35.236 62.897 9.438 1.00 7.74 ? 90 HIS A NE2 1 ATOM 529 N N . ASN A 1 91 ? 38.677 62.986 12.780 1.00 8.18 ? 91 ASN A N 1 ATOM 530 C CA . ASN A 1 91 ? 39.459 64.205 12.711 1.00 8.38 ? 91 ASN A CA 1 ATOM 531 C C . ASN A 1 91 ? 39.605 64.667 11.279 1.00 9.42 ? 91 ASN A C 1 ATOM 532 O O . ASN A 1 91 ? 40.402 64.110 10.513 1.00 12.80 ? 91 ASN A O 1 ATOM 533 C CB . ASN A 1 91 ? 40.856 63.967 13.299 1.00 8.78 ? 91 ASN A CB 1 ATOM 534 C CG . ASN A 1 91 ? 40.855 63.926 14.824 1.00 9.38 ? 91 ASN A CG 1 ATOM 535 O OD1 . ASN A 1 91 ? 41.415 64.809 15.489 1.00 9.61 ? 91 ASN A OD1 1 ATOM 536 N ND2 . ASN A 1 91 ? 40.214 62.915 15.384 1.00 9.10 ? 91 ASN A ND2 1 ATOM 537 N N . ASP A 1 92 ? 38.895 65.713 10.932 1.00 7.58 ? 92 ASP A N 1 ATOM 538 C CA . ASP A 1 92 ? 38.953 66.259 9.573 1.00 7.59 ? 92 ASP A CA 1 ATOM 539 C C . ASP A 1 92 ? 40.203 67.080 9.370 1.00 7.66 ? 92 ASP A C 1 ATOM 540 O O . ASP A 1 92 ? 40.399 68.058 10.109 1.00 8.05 ? 92 ASP A O 1 ATOM 541 C CB . ASP A 1 92 ? 37.756 67.154 9.378 1.00 7.87 ? 92 ASP A CB 1 ATOM 542 C CG . ASP A 1 92 ? 36.492 66.355 9.233 1.00 8.71 ? 92 ASP A CG 1 ATOM 543 O OD1 . ASP A 1 92 ? 36.510 65.446 8.398 1.00 8.61 ? 92 ASP A OD1 1 ATOM 544 O OD2 . ASP A 1 92 ? 35.485 66.546 9.951 1.00 11.91 ? 92 ASP A OD2 1 ATOM 545 N N . PRO A 1 93 ? 41.052 66.705 8.392 1.00 7.72 ? 93 PRO A N 1 ATOM 546 C CA . PRO A 1 93 ? 42.259 67.504 8.047 1.00 7.83 ? 93 PRO A CA 1 ATOM 547 C C . PRO A 1 93 ? 41.877 68.784 7.272 1.00 8.50 ? 93 PRO A C 1 ATOM 548 O O . PRO A 1 93 ? 42.207 68.958 6.075 1.00 10.22 ? 93 PRO A O 1 ATOM 549 C CB . PRO A 1 93 ? 43.110 66.517 7.212 1.00 8.67 ? 93 PRO A CB 1 ATOM 550 C CG . PRO A 1 93 ? 42.504 65.153 7.460 1.00 11.24 ? 93 PRO A CG 1 ATOM 551 C CD . PRO A 1 93 ? 41.027 65.428 7.634 1.00 7.90 ? 93 PRO A CD 1 ATOM 552 N N . GLY A 1 94 ? 41.164 69.675 7.960 1.00 8.11 ? 94 GLY A N 1 ATOM 553 C CA . GLY A 1 94 ? 40.566 70.878 7.369 1.00 8.03 ? 94 GLY A CA 1 ATOM 554 C C . GLY A 1 94 ? 39.087 70.642 7.126 1.00 8.96 ? 94 GLY A C 1 ATOM 555 O O . GLY A 1 94 ? 38.681 69.577 6.617 1.00 9.30 ? 94 GLY A O 1 ATOM 556 N N . TRP A 1 95 ? 38.286 71.626 7.522 1.00 8.34 ? 95 TRP A N 1 ATOM 557 C CA . TRP A 1 95 ? 36.849 71.665 7.210 1.00 8.44 ? 95 TRP A CA 1 ATOM 558 C C . TRP A 1 95 ? 36.323 73.044 7.630 1.00 8.48 ? 95 TRP A C 1 ATOM 559 O O . TRP A 1 95 ? 36.279 73.962 6.841 1.00 9.81 ? 95 TRP A O 1 ATOM 560 C CB . TRP A 1 95 ? 36.048 70.510 7.865 1.00 8.49 ? 95 TRP A CB 1 ATOM 561 C CG . TRP A 1 95 ? 34.585 70.599 7.528 1.00 8.85 ? 95 TRP A CG 1 ATOM 562 C CD1 . TRP A 1 95 ? 34.031 70.992 6.356 1.00 8.77 ? 95 TRP A CD1 1 ATOM 563 C CD2 . TRP A 1 95 ? 33.503 70.285 8.397 1.00 9.31 ? 95 TRP A CD2 1 ATOM 564 N NE1 . TRP A 1 95 ? 32.659 70.970 6.436 1.00 8.66 ? 95 TRP A NE1 1 ATOM 565 C CE2 . TRP A 1 95 ? 32.315 70.525 7.684 1.00 8.88 ? 95 TRP A CE2 1 ATOM 566 C CE3 . TRP A 1 95 ? 33.425 69.830 9.731 1.00 10.76 ? 95 TRP A CE3 1 ATOM 567 C CZ2 . TRP A 1 95 ? 31.039 70.331 8.258 1.00 9.98 ? 95 TRP A CZ2 1 ATOM 568 C CZ3 . TRP A 1 95 ? 32.152 69.634 10.297 1.00 12.07 ? 95 TRP A CZ3 1 ATOM 569 C CH2 . TRP A 1 95 ? 30.991 69.875 9.562 1.00 12.61 ? 95 TRP A CH2 1 ATOM 570 N N . ILE A 1 96 ? 35.996 73.177 8.922 1.00 9.11 ? 96 ILE A N 1 ATOM 571 C CA . ILE A 1 96 ? 35.582 74.460 9.522 1.00 11.48 ? 96 ILE A CA 1 ATOM 572 C C . ILE A 1 96 ? 36.784 75.262 10.003 1.00 11.03 ? 96 ILE A C 1 ATOM 573 O O . ILE A 1 96 ? 36.704 76.492 10.147 1.00 12.87 ? 96 ILE A O 1 ATOM 574 C CB . ILE A 1 96 ? 34.655 74.235 10.775 1.00 13.67 ? 96 ILE A CB 1 ATOM 575 C CG1 . ILE A 1 96 ? 33.424 73.420 10.441 1.00 17.01 ? 96 ILE A CG1 1 ATOM 576 C CG2 . ILE A 1 96 ? 34.284 75.563 11.469 1.00 16.15 ? 96 ILE A CG2 1 ATOM 577 C CD1 . ILE A 1 96 ? 32.820 73.839 9.161 1.00 15.77 ? 96 ILE A CD1 1 ATOM 578 N N A GLN A 1 97 ? 37.877 74.581 10.289 0.50 9.71 ? 97 GLN A N 1 ATOM 579 N N B GLN A 1 97 ? 37.872 74.560 10.280 0.50 9.71 ? 97 GLN A N 1 ATOM 580 C CA A GLN A 1 97 ? 39.162 75.222 10.560 0.50 9.74 ? 97 GLN A CA 1 ATOM 581 C CA B GLN A 1 97 ? 39.178 75.134 10.615 0.50 9.43 ? 97 GLN A CA 1 ATOM 582 C C A GLN A 1 97 ? 40.181 74.609 9.615 0.50 9.14 ? 97 GLN A C 1 ATOM 583 C C B GLN A 1 97 ? 40.198 74.572 9.640 0.50 9.09 ? 97 GLN A C 1 ATOM 584 O O A GLN A 1 97 ? 39.910 73.594 8.969 0.50 8.70 ? 97 GLN A O 1 ATOM 585 O O B GLN A 1 97 ? 39.945 73.550 8.998 0.50 8.51 ? 97 GLN A O 1 ATOM 586 C CB A GLN A 1 97 ? 39.592 75.003 12.011 0.50 10.17 ? 97 GLN A CB 1 ATOM 587 C CB B GLN A 1 97 ? 39.575 74.753 12.046 0.50 10.44 ? 97 GLN A CB 1 ATOM 588 C CG A GLN A 1 97 ? 38.529 75.366 13.045 0.50 11.67 ? 97 GLN A CG 1 ATOM 589 C CG B GLN A 1 97 ? 38.676 75.374 13.102 0.50 12.81 ? 97 GLN A CG 1 ATOM 590 C CD A GLN A 1 97 ? 39.039 75.238 14.467 0.50 11.91 ? 97 GLN A CD 1 ATOM 591 C CD B GLN A 1 97 ? 38.891 76.863 13.193 0.50 15.15 ? 97 GLN A CD 1 ATOM 592 O OE1 A GLN A 1 97 ? 40.154 75.660 14.786 0.50 15.88 ? 97 GLN A OE1 1 ATOM 593 O OE1 B GLN A 1 97 ? 39.766 77.324 13.929 0.50 18.09 ? 97 GLN A OE1 1 ATOM 594 N NE2 A GLN A 1 97 ? 38.229 74.652 15.324 0.50 13.08 ? 97 GLN A NE2 1 ATOM 595 N NE2 B GLN A 1 97 ? 38.089 77.623 12.464 0.50 16.87 ? 97 GLN A NE2 1 ATOM 596 N N . THR A 1 98 ? 41.359 75.212 9.530 1.00 8.74 ? 98 THR A N 1 ATOM 597 C CA . THR A 1 98 ? 42.421 74.639 8.710 1.00 8.62 ? 98 THR A CA 1 ATOM 598 C C . THR A 1 98 ? 43.017 73.431 9.424 1.00 8.60 ? 98 THR A C 1 ATOM 599 O O . THR A 1 98 ? 42.776 73.216 10.626 1.00 8.36 ? 98 THR A O 1 ATOM 600 C CB . THR A 1 98 ? 43.529 75.618 8.444 1.00 8.56 ? 98 THR A CB 1 ATOM 601 O OG1 . THR A 1 98 ? 44.120 75.921 9.712 1.00 9.50 ? 98 THR A OG1 1 ATOM 602 C CG2 . THR A 1 98 ? 43.015 76.931 7.861 1.00 10.31 ? 98 THR A CG2 1 ATOM 603 N N . PHE A 1 99 ? 43.782 72.633 8.684 1.00 8.21 ? 99 PHE A N 1 ATOM 604 C CA . PHE A 1 99 ? 44.538 71.546 9.259 1.00 8.26 ? 99 PHE A CA 1 ATOM 605 C C . PHE A 1 99 ? 45.320 71.995 10.491 1.00 8.27 ? 99 PHE A C 1 ATOM 606 O O . PHE A 1 99 ? 45.234 71.377 11.562 1.00 8.89 ? 99 PHE A O 1 ATOM 607 C CB . PHE A 1 99 ? 45.500 70.950 8.209 1.00 8.73 ? 99 PHE A CB 1 ATOM 608 C CG . PHE A 1 99 ? 46.368 69.867 8.733 1.00 7.65 ? 99 PHE A CG 1 ATOM 609 C CD1 . PHE A 1 99 ? 47.602 70.154 9.326 1.00 9.31 ? 99 PHE A CD1 1 ATOM 610 C CD2 . PHE A 1 99 ? 45.976 68.534 8.625 1.00 9.14 ? 99 PHE A CD2 1 ATOM 611 C CE1 . PHE A 1 99 ? 48.401 69.140 9.830 1.00 10.77 ? 99 PHE A CE1 1 ATOM 612 C CE2 . PHE A 1 99 ? 46.759 67.515 9.098 1.00 9.32 ? 99 PHE A CE2 1 ATOM 613 C CZ . PHE A 1 99 ? 47.989 67.801 9.695 1.00 9.32 ? 99 PHE A CZ 1 ATOM 614 N N . GLU A 1 100 ? 46.094 73.067 10.354 1.00 8.70 ? 100 GLU A N 1 ATOM 615 C CA . GLU A 1 100 ? 46.925 73.479 11.476 1.00 9.30 ? 100 GLU A CA 1 ATOM 616 C C . GLU A 1 100 ? 46.099 74.027 12.645 1.00 8.71 ? 100 GLU A C 1 ATOM 617 O O . GLU A 1 100 ? 46.445 73.771 13.806 1.00 9.43 ? 100 GLU A O 1 ATOM 618 C CB . GLU A 1 100 ? 47.984 74.492 11.007 1.00 10.32 ? 100 GLU A CB 1 ATOM 619 C CG . GLU A 1 100 ? 48.991 74.866 12.095 1.00 12.80 ? 100 GLU A CG 1 ATOM 620 C CD . GLU A 1 100 ? 49.865 73.722 12.560 1.00 13.87 ? 100 GLU A CD 1 ATOM 621 O OE1 . GLU A 1 100 ? 50.018 72.686 11.872 1.00 13.99 ? 100 GLU A OE1 1 ATOM 622 O OE2 . GLU A 1 100 ? 50.479 73.867 13.656 1.00 14.33 ? 100 GLU A OE2 1 ATOM 623 N N . GLU A 1 101 ? 45.014 74.733 12.366 1.00 8.81 ? 101 GLU A N 1 ATOM 624 C CA . GLU A 1 101 ? 44.133 75.197 13.443 1.00 10.53 ? 101 GLU A CA 1 ATOM 625 C C . GLU A 1 101 ? 43.526 74.059 14.216 1.00 9.99 ? 101 GLU A C 1 ATOM 626 O O . GLU A 1 101 ? 43.541 74.060 15.459 1.00 9.64 ? 101 GLU A O 1 ATOM 627 C CB . GLU A 1 101 ? 43.008 76.050 12.862 1.00 11.04 ? 101 GLU A CB 1 ATOM 628 C CG . GLU A 1 101 ? 43.411 77.471 12.466 1.00 14.53 ? 101 GLU A CG 1 ATOM 629 C CD . GLU A 1 101 ? 42.395 78.200 11.572 1.00 15.53 ? 101 GLU A CD 1 ATOM 630 O OE1 . GLU A 1 101 ? 41.392 77.644 11.034 1.00 13.19 ? 101 GLU A OE1 1 ATOM 631 O OE2 . GLU A 1 101 ? 42.593 79.434 11.402 1.00 22.76 ? 101 GLU A OE2 1 ATOM 632 N N . TYR A 1 102 ? 42.990 73.063 13.531 1.00 8.41 ? 102 TYR A N 1 ATOM 633 C CA . TYR A 1 102 ? 42.453 71.899 14.230 1.00 8.51 ? 102 TYR A CA 1 ATOM 634 C C . TYR A 1 102 ? 43.550 71.182 15.019 1.00 8.87 ? 102 TYR A C 1 ATOM 635 O O . TYR A 1 102 ? 43.301 70.693 16.106 1.00 9.26 ? 102 TYR A O 1 ATOM 636 C CB . TYR A 1 102 ? 41.862 70.908 13.239 1.00 9.29 ? 102 TYR A CB 1 ATOM 637 C CG . TYR A 1 102 ? 40.434 71.111 12.783 1.00 8.94 ? 102 TYR A CG 1 ATOM 638 C CD1 . TYR A 1 102 ? 39.386 71.305 13.674 1.00 9.31 ? 102 TYR A CD1 1 ATOM 639 C CD2 . TYR A 1 102 ? 40.127 71.000 11.443 1.00 8.16 ? 102 TYR A CD2 1 ATOM 640 C CE1 . TYR A 1 102 ? 38.069 71.436 13.213 1.00 9.90 ? 102 TYR A CE1 1 ATOM 641 C CE2 . TYR A 1 102 ? 38.840 71.105 10.985 1.00 9.16 ? 102 TYR A CE2 1 ATOM 642 C CZ . TYR A 1 102 ? 37.813 71.314 11.863 1.00 9.47 ? 102 TYR A CZ 1 ATOM 643 O OH . TYR A 1 102 ? 36.542 71.422 11.369 1.00 10.53 ? 102 TYR A OH 1 ATOM 644 N N . TYR A 1 103 ? 44.742 71.082 14.443 1.00 9.07 ? 103 TYR A N 1 ATOM 645 C CA . TYR A 1 103 ? 45.804 70.373 15.106 1.00 9.42 ? 103 TYR A CA 1 ATOM 646 C C . TYR A 1 103 ? 46.110 71.055 16.451 1.00 10.42 ? 103 TYR A C 1 ATOM 647 O O . TYR A 1 103 ? 46.216 70.411 17.456 1.00 10.13 ? 103 TYR A O 1 ATOM 648 C CB . TYR A 1 103 ? 47.062 70.343 14.248 1.00 10.31 ? 103 TYR A CB 1 ATOM 649 C CG . TYR A 1 103 ? 48.220 69.701 15.010 1.00 9.39 ? 103 TYR A CG 1 ATOM 650 C CD1 . TYR A 1 103 ? 48.246 68.342 15.290 1.00 9.21 ? 103 TYR A CD1 1 ATOM 651 C CD2 . TYR A 1 103 ? 49.252 70.470 15.514 1.00 10.33 ? 103 TYR A CD2 1 ATOM 652 C CE1 . TYR A 1 103 ? 49.249 67.785 16.003 1.00 10.39 ? 103 TYR A CE1 1 ATOM 653 C CE2 . TYR A 1 103 ? 50.292 69.904 16.244 1.00 11.02 ? 103 TYR A CE2 1 ATOM 654 C CZ . TYR A 1 103 ? 50.271 68.577 16.513 1.00 10.09 ? 103 TYR A CZ 1 ATOM 655 O OH . TYR A 1 103 ? 51.274 67.974 17.229 1.00 12.77 ? 103 TYR A OH 1 ATOM 656 N N . GLN A 1 104 ? 46.205 72.380 16.400 1.00 10.17 ? 104 GLN A N 1 ATOM 657 C CA . GLN A 1 104 ? 46.568 73.122 17.623 1.00 11.46 ? 104 GLN A CA 1 ATOM 658 C C . GLN A 1 104 ? 45.445 73.089 18.634 1.00 12.21 ? 104 GLN A C 1 ATOM 659 O O . GLN A 1 104 ? 45.699 73.029 19.863 1.00 13.83 ? 104 GLN A O 1 ATOM 660 C CB . GLN A 1 104 ? 46.921 74.567 17.255 1.00 12.00 ? 104 GLN A CB 1 ATOM 661 C CG . GLN A 1 104 ? 48.255 74.692 16.494 1.00 13.55 ? 104 GLN A CG 1 ATOM 662 C CD . GLN A 1 104 ? 49.426 74.195 17.297 1.00 13.75 ? 104 GLN A CD 1 ATOM 663 O OE1 . GLN A 1 104 ? 49.414 74.291 18.530 1.00 14.94 ? 104 GLN A OE1 1 ATOM 664 N NE2 . GLN A 1 104 ? 50.432 73.666 16.635 1.00 14.17 ? 104 GLN A NE2 1 ATOM 665 N N . HIS A 1 105 ? 44.210 73.204 18.165 1.00 12.02 ? 105 HIS A N 1 ATOM 666 C CA . HIS A 1 105 ? 43.073 73.367 19.091 1.00 13.30 ? 105 HIS A CA 1 ATOM 667 C C . HIS A 1 105 ? 42.522 72.046 19.584 1.00 13.87 ? 105 HIS A C 1 ATOM 668 O O . HIS A 1 105 ? 41.999 71.972 20.705 1.00 15.03 ? 105 HIS A O 1 ATOM 669 C CB . HIS A 1 105 ? 41.956 74.185 18.446 1.00 15.00 ? 105 HIS A CB 1 ATOM 670 C CG . HIS A 1 105 ? 42.392 75.542 17.968 1.00 20.60 ? 105 HIS A CG 1 ATOM 671 N ND1 . HIS A 1 105 ? 41.808 76.170 16.888 1.00 26.21 ? 105 HIS A ND1 1 ATOM 672 C CD2 . HIS A 1 105 ? 43.362 76.377 18.410 1.00 25.34 ? 105 HIS A CD2 1 ATOM 673 C CE1 . HIS A 1 105 ? 42.397 77.338 16.692 1.00 26.60 ? 105 HIS A CE1 1 ATOM 674 N NE2 . HIS A 1 105 ? 43.342 77.488 17.602 1.00 26.98 ? 105 HIS A NE2 1 ATOM 675 N N . ASP A 1 106 ? 42.641 70.996 18.771 1.00 12.70 ? 106 ASP A N 1 ATOM 676 C CA . ASP A 1 106 ? 41.945 69.745 19.068 1.00 11.95 ? 106 ASP A CA 1 ATOM 677 C C . ASP A 1 106 ? 42.824 68.516 18.952 1.00 10.22 ? 106 ASP A C 1 ATOM 678 O O . ASP A 1 106 ? 43.036 67.782 19.932 1.00 10.23 ? 106 ASP A O 1 ATOM 679 C CB . ASP A 1 106 ? 40.743 69.578 18.125 1.00 13.19 ? 106 ASP A CB 1 ATOM 680 C CG . ASP A 1 106 ? 39.718 70.624 18.349 1.00 17.69 ? 106 ASP A CG 1 ATOM 681 O OD1 . ASP A 1 106 ? 38.963 70.475 19.337 1.00 20.20 ? 106 ASP A OD1 1 ATOM 682 O OD2 . ASP A 1 106 ? 39.629 71.635 17.604 1.00 20.98 ? 106 ASP A OD2 1 ATOM 683 N N . THR A 1 107 ? 43.360 68.267 17.754 1.00 9.85 ? 107 THR A N 1 ATOM 684 C CA . THR A 1 107 ? 43.940 66.943 17.480 1.00 8.99 ? 107 THR A CA 1 ATOM 685 C C . THR A 1 107 ? 45.196 66.660 18.321 1.00 9.05 ? 107 THR A C 1 ATOM 686 O O . THR A 1 107 ? 45.426 65.523 18.757 1.00 8.54 ? 107 THR A O 1 ATOM 687 C CB . THR A 1 107 ? 44.232 66.801 15.983 1.00 9.00 ? 107 THR A CB 1 ATOM 688 O OG1 . THR A 1 107 ? 43.010 67.052 15.287 1.00 9.57 ? 107 THR A OG1 1 ATOM 689 C CG2 . THR A 1 107 ? 44.717 65.363 15.640 1.00 10.50 ? 107 THR A CG2 1 ATOM 690 N N . LYS A 1 108 ? 46.012 67.688 18.570 1.00 9.02 ? 108 LYS A N 1 ATOM 691 C CA . LYS A 1 108 ? 47.200 67.392 19.359 1.00 10.23 ? 108 LYS A CA 1 ATOM 692 C C . LYS A 1 108 ? 46.839 66.953 20.776 1.00 9.38 ? 108 LYS A C 1 ATOM 693 O O . LYS A 1 108 ? 47.540 66.130 21.334 1.00 11.02 ? 108 LYS A O 1 ATOM 694 C CB . LYS A 1 108 ? 48.207 68.559 19.345 1.00 10.85 ? 108 LYS A CB 1 ATOM 695 C CG . LYS A 1 108 ? 47.905 69.724 20.251 1.00 13.62 ? 108 LYS A CG 1 ATOM 696 C CD . LYS A 1 108 ? 49.012 70.789 20.072 1.00 13.68 ? 108 LYS A CD 1 ATOM 697 C CE . LYS A 1 108 ? 48.833 71.927 21.034 1.00 15.99 ? 108 LYS A CE 1 ATOM 698 N NZ . LYS A 1 108 ? 49.990 72.904 20.901 1.00 18.06 ? 108 LYS A NZ 1 ATOM 699 N N . HIS A 1 109 ? 45.745 67.494 21.286 1.00 9.60 ? 109 HIS A N 1 ATOM 700 C CA . HIS A 1 109 ? 45.246 67.111 22.618 1.00 10.31 ? 109 HIS A CA 1 ATOM 701 C C . HIS A 1 109 ? 44.647 65.724 22.613 1.00 10.03 ? 109 HIS A C 1 ATOM 702 O O . HIS A 1 109 ? 44.885 64.918 23.526 1.00 10.04 ? 109 HIS A O 1 ATOM 703 C CB . HIS A 1 109 ? 44.245 68.145 23.109 1.00 11.48 ? 109 HIS A CB 1 ATOM 704 C CG . HIS A 1 109 ? 44.833 69.512 23.171 1.00 13.97 ? 109 HIS A CG 1 ATOM 705 N ND1 . HIS A 1 109 ? 45.883 69.817 24.014 1.00 19.31 ? 109 HIS A ND1 1 ATOM 706 C CD2 . HIS A 1 109 ? 44.599 70.619 22.429 1.00 17.64 ? 109 HIS A CD2 1 ATOM 707 C CE1 . HIS A 1 109 ? 46.238 71.076 23.814 1.00 18.17 ? 109 HIS A CE1 1 ATOM 708 N NE2 . HIS A 1 109 ? 45.471 71.585 22.866 1.00 20.57 ? 109 HIS A NE2 1 ATOM 709 N N . ILE A 1 110 ? 43.865 65.416 21.573 1.00 9.75 ? 110 ILE A N 1 ATOM 710 C CA . ILE A 1 110 ? 43.306 64.075 21.425 1.00 9.27 ? 110 ILE A CA 1 ATOM 711 C C . ILE A 1 110 ? 44.417 63.023 21.413 1.00 9.75 ? 110 ILE A C 1 ATOM 712 O O . ILE A 1 110 ? 44.362 62.011 22.121 1.00 9.78 ? 110 ILE A O 1 ATOM 713 C CB . ILE A 1 110 ? 42.460 63.976 20.131 1.00 9.07 ? 110 ILE A CB 1 ATOM 714 C CG1 . ILE A 1 110 ? 41.230 64.861 20.235 1.00 8.46 ? 110 ILE A CG1 1 ATOM 715 C CG2 . ILE A 1 110 ? 42.063 62.509 19.819 1.00 9.47 ? 110 ILE A CG2 1 ATOM 716 C CD1 . ILE A 1 110 ? 40.493 65.132 18.894 1.00 9.17 ? 110 ILE A CD1 1 ATOM 717 N N . LEU A 1 111 ? 45.446 63.226 20.602 1.00 9.49 ? 111 LEU A N 1 ATOM 718 C CA . LEU A 1 111 ? 46.508 62.245 20.517 1.00 8.99 ? 111 LEU A CA 1 ATOM 719 C C . LEU A 1 111 ? 47.380 62.169 21.776 1.00 9.40 ? 111 LEU A C 1 ATOM 720 O O . LEU A 1 111 ? 47.782 61.079 22.191 1.00 9.83 ? 111 LEU A O 1 ATOM 721 C CB . LEU A 1 111 ? 47.369 62.507 19.264 1.00 8.74 ? 111 LEU A CB 1 ATOM 722 C CG . LEU A 1 111 ? 46.639 62.183 17.952 1.00 9.67 ? 111 LEU A CG 1 ATOM 723 C CD1 . LEU A 1 111 ? 47.426 62.687 16.752 1.00 10.66 ? 111 LEU A CD1 1 ATOM 724 C CD2 . LEU A 1 111 ? 46.414 60.718 17.855 1.00 11.66 ? 111 LEU A CD2 1 ATOM 725 N N . SER A 1 112 ? 47.662 63.325 22.380 1.00 9.97 ? 112 SER A N 1 ATOM 726 C CA A SER A 1 112 ? 48.423 63.321 23.619 0.50 11.20 ? 112 SER A CA 1 ATOM 727 C CA B SER A 1 112 ? 48.376 63.399 23.660 0.50 11.63 ? 112 SER A CA 1 ATOM 728 C C . SER A 1 112 ? 47.639 62.616 24.739 1.00 11.33 ? 112 SER A C 1 ATOM 729 O O . SER A 1 112 ? 48.222 61.807 25.489 1.00 12.19 ? 112 SER A O 1 ATOM 730 C CB A SER A 1 112 ? 48.811 64.741 24.002 0.50 11.34 ? 112 SER A CB 1 ATOM 731 C CB B SER A 1 112 ? 48.489 64.862 24.079 0.50 11.89 ? 112 SER A CB 1 ATOM 732 O OG A SER A 1 112 ? 49.550 64.713 25.199 0.50 11.87 ? 112 SER A OG 1 ATOM 733 O OG B SER A 1 112 ? 49.431 65.502 23.266 0.50 15.17 ? 112 SER A OG 1 ATOM 734 N N . ASN A 1 113 ? 46.339 62.871 24.826 1.00 11.09 ? 113 ASN A N 1 ATOM 735 C CA . ASN A 1 113 ? 45.555 62.218 25.865 1.00 12.28 ? 113 ASN A CA 1 ATOM 736 C C . ASN A 1 113 ? 45.295 60.762 25.534 1.00 12.46 ? 113 ASN A C 1 ATOM 737 O O . ASN A 1 113 ? 45.247 59.916 26.444 1.00 12.68 ? 113 ASN A O 1 ATOM 738 C CB . ASN A 1 113 ? 44.322 63.049 26.199 1.00 13.12 ? 113 ASN A CB 1 ATOM 739 C CG . ASN A 1 113 ? 44.723 64.392 26.849 1.00 14.17 ? 113 ASN A CG 1 ATOM 740 O OD1 . ASN A 1 113 ? 45.832 64.509 27.428 1.00 19.52 ? 113 ASN A OD1 1 ATOM 741 N ND2 . ASN A 1 113 ? 43.870 65.394 26.746 1.00 15.79 ? 113 ASN A ND2 1 ATOM 742 N N . ALA A 1 114 ? 45.238 60.403 24.241 1.00 11.60 ? 114 ALA A N 1 ATOM 743 C CA . ALA A 1 114 ? 45.105 58.988 23.899 1.00 11.93 ? 114 ALA A CA 1 ATOM 744 C C . ALA A 1 114 ? 46.342 58.225 24.333 1.00 11.56 ? 114 ALA A C 1 ATOM 745 O O . ALA A 1 114 ? 46.255 57.113 24.867 1.00 12.32 ? 114 ALA A O 1 ATOM 746 C CB . ALA A 1 114 ? 44.911 58.813 22.384 1.00 12.02 ? 114 ALA A CB 1 ATOM 747 N N . LEU A 1 115 ? 47.513 58.826 24.129 1.00 11.28 ? 115 LEU A N 1 ATOM 748 C CA . LEU A 1 115 ? 48.751 58.199 24.532 1.00 12.60 ? 115 LEU A CA 1 ATOM 749 C C . LEU A 1 115 ? 48.761 57.923 26.048 1.00 13.14 ? 115 LEU A C 1 ATOM 750 O O . LEU A 1 115 ? 49.028 56.802 26.473 1.00 14.27 ? 115 LEU A O 1 ATOM 751 C CB . LEU A 1 115 ? 49.940 59.048 24.082 1.00 13.21 ? 115 LEU A CB 1 ATOM 752 C CG . LEU A 1 115 ? 51.325 58.504 24.475 1.00 13.69 ? 115 LEU A CG 1 ATOM 753 C CD1 . LEU A 1 115 ? 51.567 57.078 24.021 1.00 16.76 ? 115 LEU A CD1 1 ATOM 754 C CD2 . LEU A 1 115 ? 52.403 59.441 23.929 1.00 15.21 ? 115 LEU A CD2 1 ATOM 755 N N . ARG A 1 116 ? 48.379 58.927 26.820 1.00 13.19 ? 116 ARG A N 1 ATOM 756 C CA . ARG A 1 116 ? 48.390 58.787 28.273 1.00 14.01 ? 116 ARG A CA 1 ATOM 757 C C . ARG A 1 116 ? 47.348 57.763 28.729 1.00 13.22 ? 116 ARG A C 1 ATOM 758 O O . ARG A 1 116 ? 47.654 56.834 29.500 1.00 13.49 ? 116 ARG A O 1 ATOM 759 C CB . ARG A 1 116 ? 48.121 60.146 28.871 1.00 15.96 ? 116 ARG A CB 1 ATOM 760 C CG . ARG A 1 116 ? 47.769 60.149 30.342 1.00 20.49 ? 116 ARG A CG 1 ATOM 761 C CD . ARG A 1 116 ? 47.057 61.433 30.763 1.00 26.58 ? 116 ARG A CD 1 ATOM 762 N NE . ARG A 1 116 ? 46.562 61.375 32.137 1.00 30.91 ? 116 ARG A NE 1 ATOM 763 C CZ . ARG A 1 116 ? 46.097 62.423 32.812 1.00 32.28 ? 116 ARG A CZ 1 ATOM 764 N NH1 . ARG A 1 116 ? 46.059 63.626 32.250 1.00 31.83 ? 116 ARG A NH1 1 ATOM 765 N NH2 . ARG A 1 116 ? 45.669 62.265 34.061 1.00 33.76 ? 116 ARG A NH2 1 ATOM 766 N N . HIS A 1 117 ? 46.117 57.917 28.262 1.00 12.79 ? 117 HIS A N 1 ATOM 767 C CA A HIS A 1 117 ? 45.054 57.048 28.731 0.50 12.73 ? 117 HIS A CA 1 ATOM 768 C CA B HIS A 1 117 ? 45.028 57.072 28.716 0.50 13.33 ? 117 HIS A CA 1 ATOM 769 C C . HIS A 1 117 ? 45.193 55.617 28.310 1.00 13.05 ? 117 HIS A C 1 ATOM 770 O O . HIS A 1 117 ? 44.909 54.723 29.104 1.00 13.46 ? 117 HIS A O 1 ATOM 771 C CB A HIS A 1 117 ? 43.690 57.611 28.398 0.50 12.98 ? 117 HIS A CB 1 ATOM 772 C CB B HIS A 1 117 ? 43.684 57.620 28.256 0.50 13.97 ? 117 HIS A CB 1 ATOM 773 C CG A HIS A 1 117 ? 43.358 58.810 29.217 0.50 11.16 ? 117 HIS A CG 1 ATOM 774 C CG B HIS A 1 117 ? 42.564 57.314 29.196 0.50 15.08 ? 117 HIS A CG 1 ATOM 775 N ND1 A HIS A 1 117 ? 42.751 58.721 30.453 0.50 11.42 ? 117 HIS A ND1 1 ATOM 776 N ND1 B HIS A 1 117 ? 42.275 58.092 30.299 0.50 15.29 ? 117 HIS A ND1 1 ATOM 777 C CD2 A HIS A 1 117 ? 43.595 60.121 29.005 0.50 11.58 ? 117 HIS A CD2 1 ATOM 778 C CD2 B HIS A 1 117 ? 41.676 56.293 29.214 0.50 17.12 ? 117 HIS A CD2 1 ATOM 779 C CE1 A HIS A 1 117 ? 42.619 59.934 30.957 0.50 10.93 ? 117 HIS A CE1 1 ATOM 780 C CE1 B HIS A 1 117 ? 41.249 57.566 30.949 0.50 16.38 ? 117 HIS A CE1 1 ATOM 781 N NE2 A HIS A 1 117 ? 43.109 60.800 30.094 0.50 11.74 ? 117 HIS A NE2 1 ATOM 782 N NE2 B HIS A 1 117 ? 40.862 56.482 30.303 0.50 16.26 ? 117 HIS A NE2 1 ATOM 783 N N . LEU A 1 118 ? 45.629 55.362 27.072 1.00 11.60 ? 118 LEU A N 1 ATOM 784 C CA . LEU A 1 118 ? 45.887 54.002 26.664 1.00 11.78 ? 118 LEU A CA 1 ATOM 785 C C . LEU A 1 118 ? 47.058 53.406 27.436 1.00 11.92 ? 118 LEU A C 1 ATOM 786 O O . LEU A 1 118 ? 47.002 52.244 27.867 1.00 13.23 ? 118 LEU A O 1 ATOM 787 C CB . LEU A 1 118 ? 46.151 53.929 25.140 1.00 11.16 ? 118 LEU A CB 1 ATOM 788 C CG . LEU A 1 118 ? 44.895 54.305 24.308 1.00 13.99 ? 118 LEU A CG 1 ATOM 789 C CD1 . LEU A 1 118 ? 45.274 54.522 22.814 1.00 14.21 ? 118 LEU A CD1 1 ATOM 790 C CD2 . LEU A 1 118 ? 43.796 53.291 24.415 1.00 14.85 ? 118 LEU A CD2 1 ATOM 791 N N . HIS A 1 119 ? 48.117 54.175 27.613 1.00 12.78 ? 119 HIS A N 1 ATOM 792 C CA . HIS A 1 119 ? 49.243 53.662 28.390 1.00 13.70 ? 119 HIS A CA 1 ATOM 793 C C . HIS A 1 119 ? 48.769 53.199 29.773 1.00 14.69 ? 119 HIS A C 1 ATOM 794 O O . HIS A 1 119 ? 49.075 52.083 30.187 1.00 15.22 ? 119 HIS A O 1 ATOM 795 C CB . HIS A 1 119 ? 50.324 54.728 28.496 1.00 15.74 ? 119 HIS A CB 1 ATOM 796 C CG . HIS A 1 119 ? 51.485 54.325 29.346 1.00 19.02 ? 119 HIS A CG 1 ATOM 797 N ND1 . HIS A 1 119 ? 51.675 54.813 30.625 1.00 24.91 ? 119 HIS A ND1 1 ATOM 798 C CD2 . HIS A 1 119 ? 52.513 53.476 29.108 1.00 23.97 ? 119 HIS A CD2 1 ATOM 799 C CE1 . HIS A 1 119 ? 52.778 54.287 31.133 1.00 25.30 ? 119 HIS A CE1 1 ATOM 800 N NE2 . HIS A 1 119 ? 53.302 53.467 30.238 1.00 25.29 ? 119 HIS A NE2 1 ATOM 801 N N . ASP A 1 120 ? 47.968 54.025 30.423 1.00 14.84 ? 120 ASP A N 1 ATOM 802 C CA . ASP A 1 120 ? 47.561 53.779 31.805 1.00 15.85 ? 120 ASP A CA 1 ATOM 803 C C . ASP A 1 120 ? 46.426 52.769 31.959 1.00 16.20 ? 120 ASP A C 1 ATOM 804 O O . ASP A 1 120 ? 46.174 52.314 33.088 1.00 16.52 ? 120 ASP A O 1 ATOM 805 C CB . ASP A 1 120 ? 47.123 55.096 32.449 1.00 16.49 ? 120 ASP A CB 1 ATOM 806 C CG . ASP A 1 120 ? 48.280 56.027 32.742 1.00 18.86 ? 120 ASP A CG 1 ATOM 807 O OD1 . ASP A 1 120 ? 49.447 55.601 32.651 1.00 22.50 ? 120 ASP A OD1 1 ATOM 808 O OD2 . ASP A 1 120 ? 48.092 57.213 33.065 1.00 21.92 ? 120 ASP A OD2 1 ATOM 809 N N . ASN A 1 121 ? 45.708 52.429 30.883 1.00 15.22 ? 121 ASN A N 1 ATOM 810 C CA . ASN A 1 121 ? 44.543 51.549 30.940 1.00 14.38 ? 121 ASN A CA 1 ATOM 811 C C . ASN A 1 121 ? 44.655 50.454 29.901 1.00 14.68 ? 121 ASN A C 1 ATOM 812 O O . ASN A 1 121 ? 44.150 50.610 28.782 1.00 14.61 ? 121 ASN A O 1 ATOM 813 C CB . ASN A 1 121 ? 43.259 52.354 30.734 1.00 13.74 ? 121 ASN A CB 1 ATOM 814 C CG . ASN A 1 121 ? 43.035 53.350 31.845 1.00 14.58 ? 121 ASN A CG 1 ATOM 815 O OD1 . ASN A 1 121 ? 42.524 52.984 32.932 1.00 17.37 ? 121 ASN A OD1 1 ATOM 816 N ND2 . ASN A 1 121 ? 43.429 54.600 31.629 1.00 13.77 ? 121 ASN A ND2 1 ATOM 817 N N . PRO A 1 122 ? 45.340 49.369 30.220 1.00 14.17 ? 122 PRO A N 1 ATOM 818 C CA . PRO A 1 122 ? 45.716 48.360 29.220 1.00 14.65 ? 122 PRO A CA 1 ATOM 819 C C . PRO A 1 122 ? 44.582 47.704 28.424 1.00 14.92 ? 122 PRO A C 1 ATOM 820 O O . PRO A 1 122 ? 44.868 47.207 27.321 1.00 16.16 ? 122 PRO A O 1 ATOM 821 C CB . PRO A 1 122 ? 46.517 47.326 30.035 1.00 15.64 ? 122 PRO A CB 1 ATOM 822 C CG . PRO A 1 122 ? 47.009 48.118 31.183 1.00 16.37 ? 122 PRO A CG 1 ATOM 823 C CD . PRO A 1 122 ? 45.876 49.031 31.566 1.00 14.23 ? 122 PRO A CD 1 ATOM 824 N N . GLU A 1 123 ? 43.354 47.684 28.940 1.00 14.09 ? 123 GLU A N 1 ATOM 825 C CA . GLU A 1 123 ? 42.223 47.119 28.182 1.00 15.18 ? 123 GLU A CA 1 ATOM 826 C C . GLU A 1 123 ? 41.504 48.111 27.265 1.00 14.15 ? 123 GLU A C 1 ATOM 827 O O . GLU A 1 123 ? 40.662 47.707 26.451 1.00 14.24 ? 123 GLU A O 1 ATOM 828 C CB . GLU A 1 123 ? 41.193 46.429 29.103 1.00 16.25 ? 123 GLU A CB 1 ATOM 829 C CG . GLU A 1 123 ? 41.723 45.271 29.959 1.00 21.58 ? 123 GLU A CG 1 ATOM 830 C CD . GLU A 1 123 ? 42.278 44.126 29.141 1.00 27.82 ? 123 GLU A CD 1 ATOM 831 O OE1 . GLU A 1 123 ? 41.570 43.622 28.242 1.00 29.57 ? 123 GLU A OE1 1 ATOM 832 O OE2 . GLU A 1 123 ? 43.434 43.713 29.400 1.00 33.45 ? 123 GLU A OE2 1 ATOM 833 N N . MET A 1 124 ? 41.810 49.396 27.420 1.00 12.68 ? 124 MET A N 1 ATOM 834 C CA . MET A 1 124 ? 41.229 50.426 26.555 1.00 12.30 ? 124 MET A CA 1 ATOM 835 C C . MET A 1 124 ? 41.845 50.343 25.150 1.00 12.09 ? 124 MET A C 1 ATOM 836 O O . MET A 1 124 ? 42.983 49.979 25.009 1.00 11.50 ? 124 MET A O 1 ATOM 837 C CB . MET A 1 124 ? 41.450 51.816 27.152 1.00 13.72 ? 124 MET A CB 1 ATOM 838 C CG . MET A 1 124 ? 40.708 52.960 26.467 1.00 15.20 ? 124 MET A CG 1 ATOM 839 S SD . MET A 1 124 ? 38.933 52.643 26.334 1.00 14.50 ? 124 MET A SD 1 ATOM 840 C CE . MET A 1 124 ? 38.417 54.171 25.505 1.00 15.73 ? 124 MET A CE 1 ATOM 841 N N . LYS A 1 125 ? 41.037 50.675 24.142 1.00 11.09 ? 125 LYS A N 1 ATOM 842 C CA . LYS A 1 125 ? 41.446 50.592 22.736 1.00 11.02 ? 125 LYS A CA 1 ATOM 843 C C . LYS A 1 125 ? 41.047 51.855 22.025 1.00 10.29 ? 125 LYS A C 1 ATOM 844 O O . LYS A 1 125 ? 40.202 52.621 22.489 1.00 10.06 ? 125 LYS A O 1 ATOM 845 C CB . LYS A 1 125 ? 40.726 49.428 22.053 1.00 11.96 ? 125 LYS A CB 1 ATOM 846 C CG . LYS A 1 125 ? 40.853 48.062 22.730 1.00 16.21 ? 125 LYS A CG 1 ATOM 847 C CD . LYS A 1 125 ? 42.224 47.531 22.511 1.00 18.37 ? 125 LYS A CD 1 ATOM 848 C CE . LYS A 1 125 ? 42.554 46.350 23.415 1.00 24.84 ? 125 LYS A CE 1 ATOM 849 N NZ . LYS A 1 125 ? 41.896 45.122 22.958 1.00 26.83 ? 125 LYS A NZ 1 ATOM 850 N N . PHE A 1 126 ? 41.661 52.069 20.844 1.00 9.96 ? 126 PHE A N 1 ATOM 851 C CA . PHE A 1 126 ? 41.357 53.301 20.074 1.00 9.15 ? 126 PHE A CA 1 ATOM 852 C C . PHE A 1 126 ? 41.832 53.054 18.660 1.00 8.29 ? 126 PHE A C 1 ATOM 853 O O . PHE A 1 126 ? 42.896 52.461 18.471 1.00 9.75 ? 126 PHE A O 1 ATOM 854 C CB . PHE A 1 126 ? 42.130 54.491 20.687 1.00 9.70 ? 126 PHE A CB 1 ATOM 855 C CG . PHE A 1 126 ? 41.745 55.879 20.213 1.00 8.54 ? 126 PHE A CG 1 ATOM 856 C CD1 . PHE A 1 126 ? 40.445 56.342 20.239 1.00 9.19 ? 126 PHE A CD1 1 ATOM 857 C CD2 . PHE A 1 126 ? 42.774 56.801 19.879 1.00 10.55 ? 126 PHE A CD2 1 ATOM 858 C CE1 . PHE A 1 126 ? 40.157 57.685 19.881 1.00 9.85 ? 126 PHE A CE1 1 ATOM 859 C CE2 . PHE A 1 126 ? 42.496 58.101 19.542 1.00 9.82 ? 126 PHE A CE2 1 ATOM 860 C CZ . PHE A 1 126 ? 41.200 58.550 19.512 1.00 9.23 ? 126 PHE A CZ 1 ATOM 861 N N . ILE A 1 127 ? 41.045 53.508 17.695 1.00 8.74 ? 127 ILE A N 1 ATOM 862 C CA . ILE A 1 127 ? 41.479 53.424 16.288 1.00 8.07 ? 127 ILE A CA 1 ATOM 863 C C . ILE A 1 127 ? 41.761 54.819 15.739 1.00 7.91 ? 127 ILE A C 1 ATOM 864 O O . ILE A 1 127 ? 41.129 55.792 16.133 1.00 8.39 ? 127 ILE A O 1 ATOM 865 C CB . ILE A 1 127 ? 40.480 52.673 15.383 1.00 8.44 ? 127 ILE A CB 1 ATOM 866 C CG1 . ILE A 1 127 ? 39.075 53.288 15.407 1.00 8.59 ? 127 ILE A CG1 1 ATOM 867 C CG2 . ILE A 1 127 ? 40.437 51.177 15.777 1.00 8.98 ? 127 ILE A CG2 1 ATOM 868 C CD1 . ILE A 1 127 ? 38.150 52.711 14.298 1.00 9.65 ? 127 ILE A CD1 1 ATOM 869 N N . TRP A 1 128 ? 42.695 54.876 14.783 1.00 7.33 ? 128 TRP A N 1 ATOM 870 C CA . TRP A 1 128 ? 43.092 56.155 14.178 1.00 7.54 ? 128 TRP A CA 1 ATOM 871 C C . TRP A 1 128 ? 43.213 55.996 12.675 1.00 7.07 ? 128 TRP A C 1 ATOM 872 O O . TRP A 1 128 ? 43.858 55.070 12.212 1.00 7.43 ? 128 TRP A O 1 ATOM 873 C CB . TRP A 1 128 ? 44.440 56.625 14.752 1.00 7.90 ? 128 TRP A CB 1 ATOM 874 C CG . TRP A 1 128 ? 44.680 58.047 14.392 1.00 7.16 ? 128 TRP A CG 1 ATOM 875 C CD1 . TRP A 1 128 ? 45.386 58.539 13.299 1.00 7.33 ? 128 TRP A CD1 1 ATOM 876 C CD2 . TRP A 1 128 ? 44.108 59.162 15.047 1.00 7.40 ? 128 TRP A CD2 1 ATOM 877 N NE1 . TRP A 1 128 ? 45.295 59.914 13.288 1.00 7.88 ? 128 TRP A NE1 1 ATOM 878 C CE2 . TRP A 1 128 ? 44.500 60.326 14.336 1.00 8.03 ? 128 TRP A CE2 1 ATOM 879 C CE3 . TRP A 1 128 ? 43.277 59.299 16.183 1.00 8.30 ? 128 TRP A CE3 1 ATOM 880 C CZ2 . TRP A 1 128 ? 44.120 61.597 14.731 1.00 8.58 ? 128 TRP A CZ2 1 ATOM 881 C CZ3 . TRP A 1 128 ? 42.891 60.545 16.564 1.00 8.66 ? 128 TRP A CZ3 1 ATOM 882 C CH2 . TRP A 1 128 ? 43.319 61.698 15.838 1.00 8.78 ? 128 TRP A CH2 1 ATOM 883 N N . ALA A 1 129 ? 42.621 56.947 11.953 1.00 7.79 ? 129 ALA A N 1 ATOM 884 C CA . ALA A 1 129 ? 42.566 56.891 10.491 1.00 8.40 ? 129 ALA A CA 1 ATOM 885 C C . ALA A 1 129 ? 43.516 57.857 9.750 1.00 9.40 ? 129 ALA A C 1 ATOM 886 O O . ALA A 1 129 ? 44.115 57.460 8.743 1.00 10.11 ? 129 ALA A O 1 ATOM 887 C CB . ALA A 1 129 ? 41.123 57.146 10.008 1.00 9.85 ? 129 ALA A CB 1 ATOM 888 N N . GLU A 1 130 ? 43.627 59.103 10.207 1.00 8.53 ? 130 GLU A N 1 ATOM 889 C CA . GLU A 1 130 ? 44.203 60.190 9.374 1.00 8.68 ? 130 GLU A CA 1 ATOM 890 C C . GLU A 1 130 ? 45.696 60.338 9.690 1.00 7.84 ? 130 GLU A C 1 ATOM 891 O O . GLU A 1 130 ? 46.086 60.928 10.724 1.00 8.13 ? 130 GLU A O 1 ATOM 892 C CB . GLU A 1 130 ? 43.469 61.506 9.619 1.00 10.14 ? 130 GLU A CB 1 ATOM 893 C CG . GLU A 1 130 ? 41.950 61.411 9.336 1.00 10.86 ? 130 GLU A CG 1 ATOM 894 C CD . GLU A 1 130 ? 41.082 60.992 10.513 1.00 13.97 ? 130 GLU A CD 1 ATOM 895 O OE1 . GLU A 1 130 ? 41.656 60.722 11.605 1.00 13.29 ? 130 GLU A OE1 1 ATOM 896 O OE2 . GLU A 1 130 ? 39.822 60.935 10.362 1.00 15.18 ? 130 GLU A OE2 1 ATOM 897 N N . ILE A 1 131 ? 46.565 59.814 8.838 1.00 7.01 ? 131 ILE A N 1 ATOM 898 C CA . ILE A 1 131 ? 47.987 59.813 9.131 1.00 7.27 ? 131 ILE A CA 1 ATOM 899 C C . ILE A 1 131 ? 48.610 61.182 8.977 1.00 7.75 ? 131 ILE A C 1 ATOM 900 O O . ILE A 1 131 ? 49.625 61.461 9.651 1.00 9.02 ? 131 ILE A O 1 ATOM 901 C CB . ILE A 1 131 ? 48.705 58.704 8.326 1.00 8.27 ? 131 ILE A CB 1 ATOM 902 C CG1 . ILE A 1 131 ? 48.065 57.344 8.625 1.00 8.64 ? 131 ILE A CG1 1 ATOM 903 C CG2 . ILE A 1 131 ? 50.199 58.658 8.632 1.00 9.25 ? 131 ILE A CG2 1 ATOM 904 C CD1 . ILE A 1 131 ? 47.944 57.016 10.144 1.00 10.93 ? 131 ILE A CD1 1 ATOM 905 N N . SER A 1 132 ? 48.019 62.073 8.203 1.00 6.95 ? 132 SER A N 1 ATOM 906 C CA . SER A 1 132 ? 48.530 63.445 8.148 1.00 7.26 ? 132 SER A CA 1 ATOM 907 C C . SER A 1 132 ? 48.627 64.041 9.559 1.00 7.50 ? 132 SER A C 1 ATOM 908 O O . SER A 1 132 ? 49.684 64.608 9.922 1.00 8.82 ? 132 SER A O 1 ATOM 909 C CB . SER A 1 132 ? 47.635 64.295 7.249 1.00 7.43 ? 132 SER A CB 1 ATOM 910 O OG . SER A 1 132 ? 46.272 64.253 7.669 1.00 7.51 ? 132 SER A OG 1 ATOM 911 N N . TYR A 1 133 ? 47.574 63.884 10.362 1.00 7.46 ? 133 TYR A N 1 ATOM 912 C CA . TYR A 1 133 ? 47.604 64.370 11.742 1.00 7.66 ? 133 TYR A CA 1 ATOM 913 C C . TYR A 1 133 ? 48.560 63.574 12.609 1.00 7.85 ? 133 TYR A C 1 ATOM 914 O O . TYR A 1 133 ? 49.250 64.175 13.463 1.00 8.99 ? 133 TYR A O 1 ATOM 915 C CB . TYR A 1 133 ? 46.224 64.299 12.374 1.00 7.75 ? 133 TYR A CB 1 ATOM 916 C CG . TYR A 1 133 ? 45.317 65.465 12.049 1.00 6.61 ? 133 TYR A CG 1 ATOM 917 C CD1 . TYR A 1 133 ? 45.712 66.786 12.305 1.00 8.99 ? 133 TYR A CD1 1 ATOM 918 C CD2 . TYR A 1 133 ? 44.047 65.246 11.506 1.00 7.10 ? 133 TYR A CD2 1 ATOM 919 C CE1 . TYR A 1 133 ? 44.861 67.833 12.045 1.00 9.25 ? 133 TYR A CE1 1 ATOM 920 C CE2 . TYR A 1 133 ? 43.199 66.280 11.236 1.00 7.67 ? 133 TYR A CE2 1 ATOM 921 C CZ . TYR A 1 133 ? 43.604 67.581 11.508 1.00 8.88 ? 133 TYR A CZ 1 ATOM 922 O OH . TYR A 1 133 ? 42.792 68.652 11.233 1.00 9.19 ? 133 TYR A OH 1 ATOM 923 N N . PHE A 1 134 ? 48.614 62.268 12.422 1.00 7.42 ? 134 PHE A N 1 ATOM 924 C CA . PHE A 1 134 ? 49.433 61.448 13.297 1.00 8.53 ? 134 PHE A CA 1 ATOM 925 C C . PHE A 1 134 ? 50.895 61.774 13.083 1.00 9.50 ? 134 PHE A C 1 ATOM 926 O O . PHE A 1 134 ? 51.676 61.887 14.064 1.00 9.82 ? 134 PHE A O 1 ATOM 927 C CB . PHE A 1 134 ? 49.144 59.954 13.116 1.00 8.66 ? 134 PHE A CB 1 ATOM 928 C CG . PHE A 1 134 ? 49.707 59.129 14.232 1.00 9.15 ? 134 PHE A CG 1 ATOM 929 C CD1 . PHE A 1 134 ? 48.959 58.929 15.397 1.00 10.28 ? 134 PHE A CD1 1 ATOM 930 C CD2 . PHE A 1 134 ? 50.992 58.649 14.158 1.00 12.74 ? 134 PHE A CD2 1 ATOM 931 C CE1 . PHE A 1 134 ? 49.516 58.201 16.471 1.00 11.71 ? 134 PHE A CE1 1 ATOM 932 C CE2 . PHE A 1 134 ? 51.568 57.926 15.234 1.00 11.91 ? 134 PHE A CE2 1 ATOM 933 C CZ . PHE A 1 134 ? 50.799 57.685 16.381 1.00 12.29 ? 134 PHE A CZ 1 ATOM 934 N N . ALA A 1 135 ? 51.299 61.951 11.827 1.00 9.30 ? 135 ALA A N 1 ATOM 935 C CA . ALA A 1 135 ? 52.684 62.311 11.498 1.00 10.13 ? 135 ALA A CA 1 ATOM 936 C C . ALA A 1 135 ? 52.997 63.699 12.053 1.00 10.17 ? 135 ALA A C 1 ATOM 937 O O . ALA A 1 135 ? 54.095 63.903 12.616 1.00 12.64 ? 135 ALA A O 1 ATOM 938 C CB . ALA A 1 135 ? 52.894 62.262 9.997 1.00 11.02 ? 135 ALA A CB 1 ATOM 939 N N . ARG A 1 136 ? 52.079 64.642 11.917 1.00 10.12 ? 136 ARG A N 1 ATOM 940 C CA . ARG A 1 136 ? 52.224 66.010 12.470 1.00 11.77 ? 136 ARG A CA 1 ATOM 941 C C . ARG A 1 136 ? 52.479 65.970 13.991 1.00 12.53 ? 136 ARG A C 1 ATOM 942 O O . ARG A 1 136 ? 53.298 66.742 14.519 1.00 14.85 ? 136 ARG A O 1 ATOM 943 C CB . ARG A 1 136 ? 50.981 66.858 12.159 1.00 12.63 ? 136 ARG A CB 1 ATOM 944 C CG . ARG A 1 136 ? 50.966 68.269 12.799 1.00 12.56 ? 136 ARG A CG 1 ATOM 945 C CD . ARG A 1 136 ? 51.859 69.289 12.068 1.00 14.25 ? 136 ARG A CD 1 ATOM 946 N NE . ARG A 1 136 ? 51.855 70.581 12.769 1.00 14.17 ? 136 ARG A NE 1 ATOM 947 C CZ . ARG A 1 136 ? 52.587 70.856 13.838 1.00 14.52 ? 136 ARG A CZ 1 ATOM 948 N NH1 . ARG A 1 136 ? 53.416 69.955 14.342 1.00 15.17 ? 136 ARG A NH1 1 ATOM 949 N NH2 . ARG A 1 136 ? 52.471 72.051 14.402 1.00 13.85 ? 136 ARG A NH2 1 ATOM 950 N N . PHE A 1 137 ? 51.794 65.071 14.699 1.00 11.24 ? 137 PHE A N 1 ATOM 951 C CA . PHE A 1 137 ? 51.907 64.906 16.139 1.00 11.24 ? 137 PHE A CA 1 ATOM 952 C C . PHE A 1 137 ? 53.204 64.190 16.499 1.00 11.87 ? 137 PHE A C 1 ATOM 953 O O . PHE A 1 137 ? 53.979 64.674 17.356 1.00 12.69 ? 137 PHE A O 1 ATOM 954 C CB . PHE A 1 137 ? 50.717 64.076 16.610 1.00 10.23 ? 137 PHE A CB 1 ATOM 955 C CG . PHE A 1 137 ? 50.748 63.798 18.071 1.00 11.74 ? 137 PHE A CG 1 ATOM 956 C CD1 . PHE A 1 137 ? 50.467 64.825 18.976 1.00 11.61 ? 137 PHE A CD1 1 ATOM 957 C CD2 . PHE A 1 137 ? 51.033 62.538 18.527 1.00 12.04 ? 137 PHE A CD2 1 ATOM 958 C CE1 . PHE A 1 137 ? 50.466 64.584 20.336 1.00 13.91 ? 137 PHE A CE1 1 ATOM 959 C CE2 . PHE A 1 137 ? 51.084 62.302 19.953 1.00 14.12 ? 137 PHE A CE2 1 ATOM 960 C CZ . PHE A 1 137 ? 50.781 63.335 20.808 1.00 12.81 ? 137 PHE A CZ 1 ATOM 961 N N . TYR A 1 138 ? 53.474 63.052 15.845 1.00 12.53 ? 138 TYR A N 1 ATOM 962 C CA A TYR A 1 138 ? 54.557 62.165 16.237 0.50 14.55 ? 138 TYR A CA 1 ATOM 963 C CA B TYR A 1 138 ? 54.594 62.159 16.177 0.50 14.91 ? 138 TYR A CA 1 ATOM 964 C C . TYR A 1 138 ? 55.910 62.878 16.107 1.00 16.09 ? 138 TYR A C 1 ATOM 965 O O . TYR A 1 138 ? 56.804 62.712 16.976 1.00 16.33 ? 138 TYR A O 1 ATOM 966 C CB A TYR A 1 138 ? 54.493 60.862 15.422 0.50 13.90 ? 138 TYR A CB 1 ATOM 967 C CB B TYR A 1 138 ? 54.679 61.002 15.188 0.50 14.65 ? 138 TYR A CB 1 ATOM 968 C CG A TYR A 1 138 ? 55.496 59.805 15.830 0.50 12.76 ? 138 TYR A CG 1 ATOM 969 C CG B TYR A 1 138 ? 55.897 60.102 15.366 0.50 14.75 ? 138 TYR A CG 1 ATOM 970 C CD1 A TYR A 1 138 ? 55.195 58.858 16.818 0.50 9.90 ? 138 TYR A CD1 1 ATOM 971 C CD1 B TYR A 1 138 ? 57.077 60.344 14.672 0.50 14.30 ? 138 TYR A CD1 1 ATOM 972 C CD2 A TYR A 1 138 ? 56.710 59.716 15.179 0.50 12.24 ? 138 TYR A CD2 1 ATOM 973 C CD2 B TYR A 1 138 ? 55.838 58.990 16.193 0.50 15.58 ? 138 TYR A CD2 1 ATOM 974 C CE1 A TYR A 1 138 ? 56.135 57.892 17.187 0.50 11.55 ? 138 TYR A CE1 1 ATOM 975 C CE1 B TYR A 1 138 ? 58.177 59.501 14.830 0.50 15.33 ? 138 TYR A CE1 1 ATOM 976 C CE2 A TYR A 1 138 ? 57.651 58.768 15.534 0.50 11.77 ? 138 TYR A CE2 1 ATOM 977 C CE2 B TYR A 1 138 ? 56.925 58.151 16.349 0.50 15.40 ? 138 TYR A CE2 1 ATOM 978 C CZ A TYR A 1 138 ? 57.356 57.847 16.519 0.50 13.06 ? 138 TYR A CZ 1 ATOM 979 C CZ B TYR A 1 138 ? 58.084 58.408 15.662 0.50 15.34 ? 138 TYR A CZ 1 ATOM 980 O OH A TYR A 1 138 ? 58.304 56.904 16.859 0.50 13.97 ? 138 TYR A OH 1 ATOM 981 O OH B TYR A 1 138 ? 59.155 57.579 15.827 0.50 17.70 ? 138 TYR A OH 1 ATOM 982 N N . HIS A 1 139 ? 56.079 63.674 15.064 1.00 16.44 ? 139 HIS A N 1 ATOM 983 C CA . HIS A 1 139 ? 57.360 64.322 14.859 1.00 18.79 ? 139 HIS A CA 1 ATOM 984 C C . HIS A 1 139 ? 57.596 65.452 15.886 1.00 19.56 ? 139 HIS A C 1 ATOM 985 O O . HIS A 1 139 ? 58.735 65.940 16.015 1.00 21.72 ? 139 HIS A O 1 ATOM 986 C CB . HIS A 1 139 ? 57.486 64.765 13.399 1.00 19.02 ? 139 HIS A CB 1 ATOM 987 C CG . HIS A 1 139 ? 57.671 63.624 12.439 1.00 20.25 ? 139 HIS A CG 1 ATOM 988 N ND1 . HIS A 1 139 ? 58.728 62.741 12.523 1.00 22.66 ? 139 HIS A ND1 1 ATOM 989 C CD2 . HIS A 1 139 ? 56.926 63.217 11.381 1.00 20.01 ? 139 HIS A CD2 1 ATOM 990 C CE1 . HIS A 1 139 ? 58.635 61.849 11.549 1.00 23.55 ? 139 HIS A CE1 1 ATOM 991 N NE2 . HIS A 1 139 ? 57.567 62.132 10.825 1.00 21.36 ? 139 HIS A NE2 1 ATOM 992 N N . ASP A 1 140 ? 56.567 65.869 16.624 1.00 19.13 ? 140 ASP A N 1 ATOM 993 C CA . ASP A 1 140 ? 56.765 66.830 17.723 1.00 19.70 ? 140 ASP A CA 1 ATOM 994 C C . ASP A 1 140 ? 56.968 66.195 19.093 1.00 18.06 ? 140 ASP A C 1 ATOM 995 O O . ASP A 1 140 ? 57.206 66.899 20.093 1.00 18.75 ? 140 ASP A O 1 ATOM 996 C CB . ASP A 1 140 ? 55.614 67.794 17.801 1.00 20.37 ? 140 ASP A CB 1 ATOM 997 C CG . ASP A 1 140 ? 55.747 68.932 16.811 1.00 23.21 ? 140 ASP A CG 1 ATOM 998 O OD1 . ASP A 1 140 ? 56.626 68.859 15.923 1.00 25.55 ? 140 ASP A OD1 1 ATOM 999 O OD2 . ASP A 1 140 ? 55.028 69.934 16.866 1.00 23.86 ? 140 ASP A OD2 1 ATOM 1000 N N . LEU A 1 141 ? 56.880 64.877 19.158 1.00 17.06 ? 141 LEU A N 1 ATOM 1001 C CA . LEU A 1 141 ? 57.111 64.144 20.397 1.00 17.54 ? 141 LEU A CA 1 ATOM 1002 C C . LEU A 1 141 ? 58.592 63.999 20.719 1.00 18.24 ? 141 LEU A C 1 ATOM 1003 O O . LEU A 1 141 ? 59.402 63.801 19.855 1.00 19.16 ? 141 LEU A O 1 ATOM 1004 C CB . LEU A 1 141 ? 56.520 62.745 20.304 1.00 17.14 ? 141 LEU A CB 1 ATOM 1005 C CG . LEU A 1 141 ? 55.006 62.605 20.291 1.00 18.34 ? 141 LEU A CG 1 ATOM 1006 C CD1 . LEU A 1 141 ? 54.655 61.148 20.186 1.00 17.44 ? 141 LEU A CD1 1 ATOM 1007 C CD2 . LEU A 1 141 ? 54.361 63.240 21.526 1.00 17.60 ? 141 LEU A CD2 1 ATOM 1008 N N . GLY A 1 142 ? 58.905 64.067 22.008 1.00 18.92 ? 142 GLY A N 1 ATOM 1009 C CA . GLY A 1 142 ? 60.200 63.640 22.508 1.00 20.76 ? 142 GLY A CA 1 ATOM 1010 C C . GLY A 1 142 ? 60.329 62.132 22.412 1.00 21.15 ? 142 GLY A C 1 ATOM 1011 O O . GLY A 1 142 ? 59.315 61.411 22.305 1.00 21.38 ? 142 GLY A O 1 ATOM 1012 N N . GLU A 1 143 ? 61.565 61.653 22.458 1.00 21.34 ? 143 GLU A N 1 ATOM 1013 C CA . GLU A 1 143 ? 61.881 60.245 22.271 1.00 21.96 ? 143 GLU A CA 1 ATOM 1014 C C . GLU A 1 143 ? 61.168 59.358 23.283 1.00 21.59 ? 143 GLU A C 1 ATOM 1015 O O . GLU A 1 143 ? 60.681 58.280 22.928 1.00 20.79 ? 143 GLU A O 1 ATOM 1016 C CB . GLU A 1 143 ? 63.404 60.024 22.312 1.00 23.24 ? 143 GLU A CB 1 ATOM 1017 C CG . GLU A 1 143 ? 63.869 58.674 21.768 1.00 27.03 ? 143 GLU A CG 1 ATOM 1018 C CD . GLU A 1 143 ? 63.513 58.432 20.303 1.00 31.88 ? 143 GLU A CD 1 ATOM 1019 O OE1 . GLU A 1 143 ? 63.354 59.408 19.522 1.00 34.48 ? 143 GLU A OE1 1 ATOM 1020 O OE2 . GLU A 1 143 ? 63.405 57.244 19.928 1.00 35.62 ? 143 GLU A OE2 1 ATOM 1021 N N . ASN A 1 144 ? 61.089 59.801 24.524 1.00 21.82 ? 144 ASN A N 1 ATOM 1022 C CA . ASN A 1 144 ? 60.392 59.059 25.557 1.00 22.31 ? 144 ASN A CA 1 ATOM 1023 C C . ASN A 1 144 ? 58.949 58.737 25.125 1.00 20.81 ? 144 ASN A C 1 ATOM 1024 O O . ASN A 1 144 ? 58.519 57.591 25.184 1.00 20.19 ? 144 ASN A O 1 ATOM 1025 C CB . ASN A 1 144 ? 60.438 59.876 26.857 1.00 23.46 ? 144 ASN A CB 1 ATOM 1026 C CG . ASN A 1 144 ? 59.832 59.164 28.033 1.00 28.42 ? 144 ASN A CG 1 ATOM 1027 O OD1 . ASN A 1 144 ? 60.420 58.240 28.598 1.00 34.55 ? 144 ASN A OD1 1 ATOM 1028 N ND2 . ASN A 1 144 ? 58.663 59.623 28.448 1.00 32.22 ? 144 ASN A ND2 1 ATOM 1029 N N . LYS A 1 145 ? 58.233 59.762 24.674 1.00 20.06 ? 145 LYS A N 1 ATOM 1030 C CA . LYS A 1 145 ? 56.846 59.613 24.221 1.00 18.49 ? 145 LYS A CA 1 ATOM 1031 C C . LYS A 1 145 ? 56.725 58.827 22.900 1.00 17.78 ? 145 LYS A C 1 ATOM 1032 O O . LYS A 1 145 ? 55.776 58.047 22.759 1.00 16.82 ? 145 LYS A O 1 ATOM 1033 C CB . LYS A 1 145 ? 56.125 60.964 24.123 1.00 18.64 ? 145 LYS A CB 1 ATOM 1034 C CG . LYS A 1 145 ? 55.920 61.675 25.464 1.00 21.27 ? 145 LYS A CG 1 ATOM 1035 C CD . LYS A 1 145 ? 54.687 61.168 26.188 1.00 26.95 ? 145 LYS A CD 1 ATOM 1036 C CE . LYS A 1 145 ? 54.360 62.056 27.384 1.00 30.49 ? 145 LYS A CE 1 ATOM 1037 N NZ . LYS A 1 145 ? 55.078 61.609 28.610 1.00 34.62 ? 145 LYS A NZ 1 ATOM 1038 N N . LYS A 1 146 ? 57.659 59.025 21.964 1.00 17.28 ? 146 LYS A N 1 ATOM 1039 C CA . LYS A 1 146 ? 57.692 58.213 20.732 1.00 17.32 ? 146 LYS A CA 1 ATOM 1040 C C . LYS A 1 146 ? 57.740 56.732 21.077 1.00 17.50 ? 146 LYS A C 1 ATOM 1041 O O . LYS A 1 146 ? 56.991 55.920 20.507 1.00 17.01 ? 146 LYS A O 1 ATOM 1042 C CB . LYS A 1 146 ? 58.853 58.569 19.810 1.00 17.05 ? 146 LYS A CB 1 ATOM 1043 C CG . LYS A 1 146 ? 58.764 59.906 19.117 1.00 16.28 ? 146 LYS A CG 1 ATOM 1044 C CD . LYS A 1 146 ? 59.942 60.068 18.153 1.00 17.09 ? 146 LYS A CD 1 ATOM 1045 C CE . LYS A 1 146 ? 59.822 61.337 17.292 1.00 20.10 ? 146 LYS A CE 1 ATOM 1046 N NZ . LYS A 1 146 ? 61.085 61.589 16.573 1.00 24.53 ? 146 LYS A NZ 1 ATOM 1047 N N . LEU A 1 147 ? 58.598 56.369 22.029 1.00 18.00 ? 147 LEU A N 1 ATOM 1048 C CA . LEU A 1 147 ? 58.732 54.972 22.448 1.00 17.89 ? 147 LEU A CA 1 ATOM 1049 C C . LEU A 1 147 ? 57.439 54.443 23.102 1.00 17.41 ? 147 LEU A C 1 ATOM 1050 O O . LEU A 1 147 ? 57.014 53.316 22.806 1.00 17.74 ? 147 LEU A O 1 ATOM 1051 C CB . LEU A 1 147 ? 59.955 54.789 23.384 1.00 18.81 ? 147 LEU A CB 1 ATOM 1052 C CG . LEU A 1 147 ? 61.351 54.855 22.756 1.00 21.20 ? 147 LEU A CG 1 ATOM 1053 C CD1 . LEU A 1 147 ? 62.392 54.910 23.855 1.00 23.24 ? 147 LEU A CD1 1 ATOM 1054 C CD2 . LEU A 1 147 ? 61.624 53.668 21.849 1.00 24.09 ? 147 LEU A CD2 1 ATOM 1055 N N . GLN A 1 148 ? 56.823 55.246 23.968 1.00 17.11 ? 148 GLN A N 1 ATOM 1056 C CA . GLN A 1 148 ? 55.541 54.878 24.566 1.00 17.41 ? 148 GLN A CA 1 ATOM 1057 C C . GLN A 1 148 ? 54.467 54.677 23.485 1.00 16.24 ? 148 GLN A C 1 ATOM 1058 O O . GLN A 1 148 ? 53.681 53.748 23.573 1.00 16.24 ? 148 GLN A O 1 ATOM 1059 C CB . GLN A 1 148 ? 55.072 55.944 25.527 1.00 18.34 ? 148 GLN A CB 1 ATOM 1060 C CG . GLN A 1 148 ? 55.798 55.978 26.843 1.00 22.84 ? 148 GLN A CG 1 ATOM 1061 C CD . GLN A 1 148 ? 55.082 56.870 27.829 1.00 27.82 ? 148 GLN A CD 1 ATOM 1062 O OE1 . GLN A 1 148 ? 54.219 57.674 27.440 1.00 31.09 ? 148 GLN A OE1 1 ATOM 1063 N NE2 . GLN A 1 148 ? 55.421 56.732 29.110 1.00 30.50 ? 148 GLN A NE2 1 ATOM 1064 N N . MET A 1 149 ? 54.462 55.561 22.487 1.00 15.33 ? 149 MET A N 1 ATOM 1065 C CA . MET A 1 149 ? 53.512 55.433 21.369 1.00 14.34 ? 149 MET A CA 1 ATOM 1066 C C . MET A 1 149 ? 53.739 54.141 20.590 1.00 14.83 ? 149 MET A C 1 ATOM 1067 O O . MET A 1 149 ? 52.786 53.396 20.297 1.00 14.16 ? 149 MET A O 1 ATOM 1068 C CB . MET A 1 149 ? 53.639 56.640 20.454 1.00 15.18 ? 149 MET A CB 1 ATOM 1069 C CG . MET A 1 149 ? 52.621 56.668 19.312 1.00 13.79 ? 149 MET A CG 1 ATOM 1070 S SD . MET A 1 149 ? 50.921 56.874 19.910 1.00 16.06 ? 149 MET A SD 1 ATOM 1071 C CE . MET A 1 149 ? 50.779 58.650 19.990 1.00 19.26 ? 149 MET A CE 1 ATOM 1072 N N . LYS A 1 150 ? 54.995 53.855 20.245 1.00 15.15 ? 150 LYS A N 1 ATOM 1073 C CA . LYS A 1 150 ? 55.283 52.628 19.500 1.00 16.17 ? 150 LYS A CA 1 ATOM 1074 C C . LYS A 1 150 ? 54.810 51.405 20.288 1.00 15.67 ? 150 LYS A C 1 ATOM 1075 O O . LYS A 1 150 ? 54.335 50.434 19.698 1.00 16.11 ? 150 LYS A O 1 ATOM 1076 C CB . LYS A 1 150 ? 56.759 52.471 19.111 1.00 16.67 ? 150 LYS A CB 1 ATOM 1077 C CG . LYS A 1 150 ? 57.282 53.502 18.149 1.00 19.58 ? 150 LYS A CG 1 ATOM 1078 C CD . LYS A 1 150 ? 58.739 53.207 17.861 1.00 26.28 ? 150 LYS A CD 1 ATOM 1079 C CE . LYS A 1 150 ? 59.591 54.420 18.131 1.00 31.04 ? 150 LYS A CE 1 ATOM 1080 N NZ . LYS A 1 150 ? 61.015 54.169 17.772 1.00 33.39 ? 150 LYS A NZ 1 ATOM 1081 N N A SER A 1 151 ? 54.906 51.465 21.615 0.50 15.66 ? 151 SER A N 1 ATOM 1082 N N B SER A 1 151 ? 54.932 51.457 21.614 0.50 15.54 ? 151 SER A N 1 ATOM 1083 C CA A SER A 1 151 ? 54.535 50.342 22.478 0.50 15.86 ? 151 SER A CA 1 ATOM 1084 C CA B SER A 1 151 ? 54.528 50.334 22.457 0.50 15.61 ? 151 SER A CA 1 ATOM 1085 C C A SER A 1 151 ? 53.018 50.077 22.547 0.50 15.06 ? 151 SER A C 1 ATOM 1086 C C B SER A 1 151 ? 53.022 50.078 22.419 0.50 14.80 ? 151 SER A C 1 ATOM 1087 O O A SER A 1 151 ? 52.581 48.926 22.600 0.50 15.27 ? 151 SER A O 1 ATOM 1088 O O B SER A 1 151 ? 52.604 48.926 22.247 0.50 14.86 ? 151 SER A O 1 ATOM 1089 C CB A SER A 1 151 ? 55.124 50.535 23.880 0.50 16.66 ? 151 SER A CB 1 ATOM 1090 C CB B SER A 1 151 ? 55.012 50.495 23.901 0.50 16.45 ? 151 SER A CB 1 ATOM 1091 O OG A SER A 1 151 ? 54.343 51.435 24.639 0.50 17.82 ? 151 SER A OG 1 ATOM 1092 O OG B SER A 1 151 ? 54.952 49.242 24.567 0.50 16.95 ? 151 SER A OG 1 ATOM 1093 N N . ILE A 1 152 ? 52.215 51.137 22.562 1.00 14.37 ? 152 ILE A N 1 ATOM 1094 C CA . ILE A 1 152 ? 50.752 50.959 22.535 1.00 13.77 ? 152 ILE A CA 1 ATOM 1095 C C . ILE A 1 152 ? 50.241 50.558 21.138 1.00 12.62 ? 152 ILE A C 1 ATOM 1096 O O . ILE A 1 152 ? 49.163 49.978 21.028 1.00 14.02 ? 152 ILE A O 1 ATOM 1097 C CB . ILE A 1 152 ? 49.941 52.141 23.146 1.00 13.97 ? 152 ILE A CB 1 ATOM 1098 C CG1 . ILE A 1 152 ? 50.165 53.444 22.404 1.00 14.88 ? 152 ILE A CG1 1 ATOM 1099 C CG2 . ILE A 1 152 ? 50.263 52.277 24.657 1.00 14.80 ? 152 ILE A CG2 1 ATOM 1100 C CD1 . ILE A 1 152 ? 49.110 54.522 22.695 1.00 14.42 ? 152 ILE A CD1 1 ATOM 1101 N N . VAL A 1 153 ? 51.021 50.859 20.105 1.00 12.86 ? 153 VAL A N 1 ATOM 1102 C CA . VAL A 1 153 ? 50.736 50.336 18.757 1.00 13.89 ? 153 VAL A CA 1 ATOM 1103 C C . VAL A 1 153 ? 51.131 48.871 18.650 1.00 15.11 ? 153 VAL A C 1 ATOM 1104 O O . VAL A 1 153 ? 50.334 48.028 18.210 1.00 14.99 ? 153 VAL A O 1 ATOM 1105 C CB . VAL A 1 153 ? 51.400 51.209 17.678 1.00 13.42 ? 153 VAL A CB 1 ATOM 1106 C CG1 . VAL A 1 153 ? 51.259 50.579 16.285 1.00 14.93 ? 153 VAL A CG1 1 ATOM 1107 C CG2 . VAL A 1 153 ? 50.781 52.586 17.697 1.00 13.41 ? 153 VAL A CG2 1 ATOM 1108 N N A LYS A 1 154 ? 52.351 48.550 19.074 0.50 15.66 ? 154 LYS A N 1 ATOM 1109 N N B LYS A 1 154 ? 52.356 48.552 19.066 0.50 15.67 ? 154 LYS A N 1 ATOM 1110 C CA A LYS A 1 154 ? 52.837 47.173 19.003 0.50 17.04 ? 154 LYS A CA 1 ATOM 1111 C CA B LYS A 1 154 ? 52.829 47.168 19.024 0.50 17.05 ? 154 LYS A CA 1 ATOM 1112 C C A LYS A 1 154 ? 51.997 46.182 19.826 0.50 17.19 ? 154 LYS A C 1 ATOM 1113 C C B LYS A 1 154 ? 51.915 46.207 19.785 0.50 17.22 ? 154 LYS A C 1 ATOM 1114 O O A LYS A 1 154 ? 51.842 45.023 19.423 0.50 17.93 ? 154 LYS A O 1 ATOM 1115 O O B LYS A 1 154 ? 51.637 45.099 19.309 0.50 18.06 ? 154 LYS A O 1 ATOM 1116 C CB A LYS A 1 154 ? 54.317 47.113 19.395 0.50 17.49 ? 154 LYS A CB 1 ATOM 1117 C CB B LYS A 1 154 ? 54.257 47.063 19.562 0.50 17.53 ? 154 LYS A CB 1 ATOM 1118 C CG A LYS A 1 154 ? 55.025 45.814 18.993 0.50 19.97 ? 154 LYS A CG 1 ATOM 1119 C CG B LYS A 1 154 ? 54.875 45.689 19.326 0.50 19.86 ? 154 LYS A CG 1 ATOM 1120 C CD A LYS A 1 154 ? 56.540 45.986 18.891 0.50 22.58 ? 154 LYS A CD 1 ATOM 1121 C CD B LYS A 1 154 ? 56.314 45.636 19.769 0.50 21.53 ? 154 LYS A CD 1 ATOM 1122 C CE A LYS A 1 154 ? 57.193 46.431 20.193 0.50 24.79 ? 154 LYS A CE 1 ATOM 1123 C CE B LYS A 1 154 ? 57.013 44.389 19.231 0.50 22.69 ? 154 LYS A CE 1 ATOM 1124 N NZ A LYS A 1 154 ? 56.653 45.768 21.414 0.50 26.42 ? 154 LYS A NZ 1 ATOM 1125 N NZ B LYS A 1 154 ? 57.189 44.419 17.744 0.50 23.93 ? 154 LYS A NZ 1 ATOM 1126 N N . ASN A 1 155 ? 51.447 46.630 20.955 1.00 17.45 ? 155 ASN A N 1 ATOM 1127 C CA . ASN A 1 155 ? 50.588 45.787 21.805 1.00 17.94 ? 155 ASN A CA 1 ATOM 1128 C C . ASN A 1 155 ? 49.108 45.780 21.384 1.00 17.71 ? 155 ASN A C 1 ATOM 1129 O O . ASN A 1 155 ? 48.287 45.109 22.002 1.00 18.57 ? 155 ASN A O 1 ATOM 1130 C CB . ASN A 1 155 ? 50.736 46.152 23.307 1.00 19.82 ? 155 ASN A CB 1 ATOM 1131 C CG . ASN A 1 155 ? 49.885 47.358 23.732 1.00 21.63 ? 155 ASN A CG 1 ATOM 1132 O OD1 . ASN A 1 155 ? 49.145 47.918 22.932 1.00 23.74 ? 155 ASN A OD1 1 ATOM 1133 N ND2 . ASN A 1 155 ? 49.990 47.761 25.002 1.00 22.42 ? 155 ASN A ND2 1 ATOM 1134 N N . GLY A 1 156 ? 48.766 46.555 20.354 1.00 14.86 ? 156 GLY A N 1 ATOM 1135 C CA . GLY A 1 156 ? 47.432 46.514 19.750 1.00 15.14 ? 156 GLY A CA 1 ATOM 1136 C C . GLY A 1 156 ? 46.372 47.350 20.423 1.00 14.17 ? 156 GLY A C 1 ATOM 1137 O O . GLY A 1 156 ? 45.190 47.206 20.090 1.00 15.87 ? 156 GLY A O 1 ATOM 1138 N N . GLN A 1 157 ? 46.737 48.229 21.339 1.00 12.19 ? 157 GLN A N 1 ATOM 1139 C CA . GLN A 1 157 ? 45.760 49.127 21.918 1.00 11.53 ? 157 GLN A CA 1 ATOM 1140 C C . GLN A 1 157 ? 45.354 50.262 20.991 1.00 10.65 ? 157 GLN A C 1 ATOM 1141 O O . GLN A 1 157 ? 44.207 50.617 20.934 1.00 10.70 ? 157 GLN A O 1 ATOM 1142 C CB . GLN A 1 157 ? 46.296 49.741 23.200 1.00 11.14 ? 157 GLN A CB 1 ATOM 1143 C CG . GLN A 1 157 ? 46.244 48.836 24.409 1.00 12.56 ? 157 GLN A CG 1 ATOM 1144 C CD . GLN A 1 157 ? 46.646 49.580 25.657 1.00 11.48 ? 157 GLN A CD 1 ATOM 1145 O OE1 . GLN A 1 157 ? 47.794 49.570 26.049 1.00 14.15 ? 157 GLN A OE1 1 ATOM 1146 N NE2 . GLN A 1 157 ? 45.705 50.268 26.244 1.00 12.61 ? 157 GLN A NE2 1 ATOM 1147 N N . LEU A 1 158 ? 46.346 50.869 20.346 1.00 10.35 ? 158 LEU A N 1 ATOM 1148 C CA A LEU A 1 158 ? 46.065 51.871 19.321 0.50 10.11 ? 158 LEU A CA 1 ATOM 1149 C CA B LEU A 1 158 ? 46.120 51.880 19.318 0.50 9.54 ? 158 LEU A CA 1 ATOM 1150 C C . LEU A 1 158 ? 46.296 51.195 17.981 1.00 9.94 ? 158 LEU A C 1 ATOM 1151 O O . LEU A 1 158 ? 47.361 50.652 17.700 1.00 11.01 ? 158 LEU A O 1 ATOM 1152 C CB A LEU A 1 158 ? 46.920 53.127 19.498 0.50 10.71 ? 158 LEU A CB 1 ATOM 1153 C CB B LEU A 1 158 ? 47.154 52.983 19.450 0.50 9.51 ? 158 LEU A CB 1 ATOM 1154 C CG A LEU A 1 158 ? 46.555 54.330 18.611 0.50 12.64 ? 158 LEU A CG 1 ATOM 1155 C CG B LEU A 1 158 ? 47.106 54.064 18.372 0.50 9.37 ? 158 LEU A CG 1 ATOM 1156 C CD1 A LEU A 1 158 ? 47.017 55.640 19.235 0.50 15.66 ? 158 LEU A CD1 1 ATOM 1157 C CD1 B LEU A 1 158 ? 45.716 54.712 18.366 0.50 9.48 ? 158 LEU A CD1 1 ATOM 1158 C CD2 A LEU A 1 158 ? 47.120 54.164 17.204 0.50 16.08 ? 158 LEU A CD2 1 ATOM 1159 C CD2 B LEU A 1 158 ? 48.199 55.088 18.628 0.50 10.01 ? 158 LEU A CD2 1 ATOM 1160 N N . GLU A 1 159 ? 45.246 51.211 17.171 1.00 9.05 ? 159 GLU A N 1 ATOM 1161 C CA . GLU A 1 159 ? 45.299 50.540 15.874 1.00 9.60 ? 159 GLU A CA 1 ATOM 1162 C C . GLU A 1 159 ? 44.980 51.525 14.764 1.00 8.75 ? 159 GLU A C 1 ATOM 1163 O O . GLU A 1 159 ? 43.983 52.249 14.796 1.00 9.13 ? 159 GLU A O 1 ATOM 1164 C CB . GLU A 1 159 ? 44.284 49.405 15.830 1.00 10.47 ? 159 GLU A CB 1 ATOM 1165 C CG . GLU A 1 159 ? 44.274 48.633 14.526 1.00 11.59 ? 159 GLU A CG 1 ATOM 1166 C CD . GLU A 1 159 ? 43.291 47.497 14.578 1.00 14.36 ? 159 GLU A CD 1 ATOM 1167 O OE1 . GLU A 1 159 ? 43.584 46.479 15.263 1.00 14.21 ? 159 GLU A OE1 1 ATOM 1168 O OE2 . GLU A 1 159 ? 42.229 47.630 13.955 1.00 12.28 ? 159 GLU A OE2 1 ATOM 1169 N N . PHE A 1 160 ? 45.833 51.520 13.753 1.00 7.88 ? 160 PHE A N 1 ATOM 1170 C CA . PHE A 1 160 ? 45.611 52.330 12.565 1.00 8.07 ? 160 PHE A CA 1 ATOM 1171 C C . PHE A 1 160 ? 44.660 51.611 11.628 1.00 8.08 ? 160 PHE A C 1 ATOM 1172 O O . PHE A 1 160 ? 44.817 50.415 11.355 1.00 8.31 ? 160 PHE A O 1 ATOM 1173 C CB . PHE A 1 160 ? 46.938 52.703 11.891 1.00 8.81 ? 160 PHE A CB 1 ATOM 1174 C CG . PHE A 1 160 ? 47.813 53.528 12.768 1.00 8.47 ? 160 PHE A CG 1 ATOM 1175 C CD1 . PHE A 1 160 ? 47.544 54.865 12.973 1.00 9.65 ? 160 PHE A CD1 1 ATOM 1176 C CD2 . PHE A 1 160 ? 48.854 52.936 13.459 1.00 9.89 ? 160 PHE A CD2 1 ATOM 1177 C CE1 . PHE A 1 160 ? 48.318 55.620 13.831 1.00 10.25 ? 160 PHE A CE1 1 ATOM 1178 C CE2 . PHE A 1 160 ? 49.639 53.683 14.295 1.00 10.59 ? 160 PHE A CE2 1 ATOM 1179 C CZ . PHE A 1 160 ? 49.364 55.014 14.483 1.00 11.05 ? 160 PHE A CZ 1 ATOM 1180 N N . VAL A 1 161 ? 43.699 52.379 11.140 1.00 7.28 ? 161 VAL A N 1 ATOM 1181 C CA . VAL A 1 161 ? 42.705 51.877 10.207 1.00 7.30 ? 161 VAL A CA 1 ATOM 1182 C C . VAL A 1 161 ? 42.869 52.671 8.915 1.00 7.28 ? 161 VAL A C 1 ATOM 1183 O O . VAL A 1 161 ? 43.012 53.891 8.920 1.00 8.95 ? 161 VAL A O 1 ATOM 1184 C CB . VAL A 1 161 ? 41.253 51.958 10.791 1.00 7.73 ? 161 VAL A CB 1 ATOM 1185 C CG1 . VAL A 1 161 ? 41.133 50.969 11.940 1.00 8.72 ? 161 VAL A CG1 1 ATOM 1186 C CG2 . VAL A 1 161 ? 40.895 53.335 11.282 1.00 7.95 ? 161 VAL A CG2 1 ATOM 1187 N N . THR A 1 162 ? 42.939 51.908 7.814 1.00 7.67 ? 162 THR A N 1 ATOM 1188 C CA . THR A 1 162 ? 43.292 52.414 6.463 1.00 8.13 ? 162 THR A CA 1 ATOM 1189 C C . THR A 1 162 ? 44.758 52.829 6.407 1.00 7.19 ? 162 THR A C 1 ATOM 1190 O O . THR A 1 162 ? 45.562 52.284 5.650 1.00 8.49 ? 162 THR A O 1 ATOM 1191 C CB . THR A 1 162 ? 42.404 53.548 5.941 1.00 8.51 ? 162 THR A CB 1 ATOM 1192 O OG1 . THR A 1 162 ? 41.019 53.172 6.056 1.00 9.46 ? 162 THR A OG1 1 ATOM 1193 C CG2 . THR A 1 162 ? 42.671 53.761 4.410 1.00 10.84 ? 162 THR A CG2 1 ATOM 1194 N N . GLY A 1 163 ? 45.069 53.887 7.135 1.00 7.37 ? 163 GLY A N 1 ATOM 1195 C CA . GLY A 1 163 ? 46.440 54.393 7.179 1.00 7.53 ? 163 GLY A CA 1 ATOM 1196 C C . GLY A 1 163 ? 46.799 55.300 6.017 1.00 6.73 ? 163 GLY A C 1 ATOM 1197 O O . GLY A 1 163 ? 47.972 55.505 5.712 1.00 8.23 ? 163 GLY A O 1 ATOM 1198 N N . GLY A 1 164 ? 45.784 55.858 5.349 1.00 6.46 ? 164 GLY A N 1 ATOM 1199 C CA . GLY A 1 164 ? 46.039 56.906 4.378 1.00 6.85 ? 164 GLY A CA 1 ATOM 1200 C C . GLY A 1 164 ? 46.355 58.243 5.015 1.00 6.63 ? 164 GLY A C 1 ATOM 1201 O O . GLY A 1 164 ? 46.077 58.478 6.211 1.00 6.82 ? 164 GLY A O 1 ATOM 1202 N N . TRP A 1 165 ? 46.959 59.147 4.231 1.00 6.12 ? 165 TRP A N 1 ATOM 1203 C CA . TRP A 1 165 ? 47.201 60.496 4.713 1.00 5.74 ? 165 TRP A CA 1 ATOM 1204 C C . TRP A 1 165 ? 45.884 61.107 5.187 1.00 6.26 ? 165 TRP A C 1 ATOM 1205 O O . TRP A 1 165 ? 45.859 61.867 6.179 1.00 6.81 ? 165 TRP A O 1 ATOM 1206 C CB . TRP A 1 165 ? 47.798 61.303 3.566 1.00 6.77 ? 165 TRP A CB 1 ATOM 1207 C CG . TRP A 1 165 ? 48.636 62.444 4.005 1.00 7.05 ? 165 TRP A CG 1 ATOM 1208 C CD1 . TRP A 1 165 ? 48.437 63.770 3.717 1.00 8.54 ? 165 TRP A CD1 1 ATOM 1209 C CD2 . TRP A 1 165 ? 49.835 62.384 4.806 1.00 7.62 ? 165 TRP A CD2 1 ATOM 1210 N NE1 . TRP A 1 165 ? 49.451 64.539 4.259 1.00 9.64 ? 165 TRP A NE1 1 ATOM 1211 C CE2 . TRP A 1 165 ? 50.302 63.718 4.945 1.00 7.73 ? 165 TRP A CE2 1 ATOM 1212 C CE3 . TRP A 1 165 ? 50.570 61.340 5.380 1.00 9.27 ? 165 TRP A CE3 1 ATOM 1213 C CZ2 . TRP A 1 165 ? 51.477 64.038 5.691 1.00 10.17 ? 165 TRP A CZ2 1 ATOM 1214 C CZ3 . TRP A 1 165 ? 51.739 61.670 6.117 1.00 11.78 ? 165 TRP A CZ3 1 ATOM 1215 C CH2 . TRP A 1 165 ? 52.163 63.001 6.227 1.00 10.30 ? 165 TRP A CH2 1 ATOM 1216 N N . VAL A 1 166 ? 44.787 60.800 4.467 1.00 5.73 ? 166 VAL A N 1 ATOM 1217 C CA . VAL A 1 166 ? 43.451 61.314 4.792 1.00 6.37 ? 166 VAL A CA 1 ATOM 1218 C C . VAL A 1 166 ? 42.453 60.171 4.638 1.00 6.24 ? 166 VAL A C 1 ATOM 1219 O O . VAL A 1 166 ? 42.832 59.052 4.311 1.00 6.99 ? 166 VAL A O 1 ATOM 1220 C CB . VAL A 1 166 ? 43.034 62.500 3.868 1.00 6.35 ? 166 VAL A CB 1 ATOM 1221 C CG1 . VAL A 1 166 ? 44.020 63.674 3.984 1.00 7.13 ? 166 VAL A CG1 1 ATOM 1222 C CG2 . VAL A 1 166 ? 42.985 62.036 2.404 1.00 7.58 ? 166 VAL A CG2 1 ATOM 1223 N N . MET A 1 167 ? 41.182 60.491 4.908 1.00 6.60 ? 167 MET A N 1 ATOM 1224 C CA . MET A 1 167 ? 40.073 59.622 4.528 1.00 5.75 ? 167 MET A CA 1 ATOM 1225 C C . MET A 1 167 ? 39.445 60.277 3.300 1.00 5.75 ? 167 MET A C 1 ATOM 1226 O O . MET A 1 167 ? 38.697 61.257 3.441 1.00 6.66 ? 167 MET A O 1 ATOM 1227 C CB . MET A 1 167 ? 39.082 59.586 5.679 1.00 6.69 ? 167 MET A CB 1 ATOM 1228 C CG . MET A 1 167 ? 37.823 58.741 5.417 1.00 6.84 ? 167 MET A CG 1 ATOM 1229 S SD . MET A 1 167 ? 36.641 58.796 6.770 1.00 8.23 ? 167 MET A SD 1 ATOM 1230 C CE . MET A 1 167 ? 37.606 58.072 8.093 1.00 9.44 ? 167 MET A CE 1 ATOM 1231 N N . PRO A 1 168 ? 39.817 59.841 2.101 1.00 5.98 ? 168 PRO A N 1 ATOM 1232 C CA . PRO A 1 168 ? 39.500 60.652 0.936 1.00 6.27 ? 168 PRO A CA 1 ATOM 1233 C C . PRO A 1 168 ? 38.059 60.651 0.502 1.00 6.52 ? 168 PRO A C 1 ATOM 1234 O O . PRO A 1 168 ? 37.326 59.694 0.719 1.00 6.38 ? 168 PRO A O 1 ATOM 1235 C CB . PRO A 1 168 ? 40.363 60.020 -0.172 1.00 6.96 ? 168 PRO A CB 1 ATOM 1236 C CG . PRO A 1 168 ? 40.488 58.597 0.235 1.00 8.23 ? 168 PRO A CG 1 ATOM 1237 C CD . PRO A 1 168 ? 40.636 58.649 1.774 1.00 6.75 ? 168 PRO A CD 1 ATOM 1238 N N . ASP A 1 169 ? 37.679 61.725 -0.174 1.00 6.27 ? 169 ASP A N 1 ATOM 1239 C CA . ASP A 1 169 ? 36.500 61.690 -1.024 1.00 5.67 ? 169 ASP A CA 1 ATOM 1240 C C . ASP A 1 169 ? 36.620 60.518 -1.977 1.00 6.41 ? 169 ASP A C 1 ATOM 1241 O O . ASP A 1 169 ? 37.719 60.194 -2.428 1.00 6.04 ? 169 ASP A O 1 ATOM 1242 C CB . ASP A 1 169 ? 36.476 62.992 -1.842 1.00 6.16 ? 169 ASP A CB 1 ATOM 1243 C CG . ASP A 1 169 ? 35.320 63.079 -2.793 1.00 7.34 ? 169 ASP A CG 1 ATOM 1244 O OD1 . ASP A 1 169 ? 34.205 62.586 -2.469 1.00 7.80 ? 169 ASP A OD1 1 ATOM 1245 O OD2 . ASP A 1 169 ? 35.450 63.668 -3.882 1.00 8.69 ? 169 ASP A OD2 1 ATOM 1246 N N . GLU A 1 170 ? 35.486 59.938 -2.333 1.00 5.99 ? 170 GLU A N 1 ATOM 1247 C CA . GLU A 1 170 ? 35.445 58.815 -3.286 1.00 6.25 ? 170 GLU A CA 1 ATOM 1248 C C . GLU A 1 170 ? 34.738 59.189 -4.589 1.00 5.78 ? 170 GLU A C 1 ATOM 1249 O O . GLU A 1 170 ? 34.768 58.390 -5.528 1.00 6.57 ? 170 GLU A O 1 ATOM 1250 C CB . GLU A 1 170 ? 34.827 57.573 -2.633 1.00 6.72 ? 170 GLU A CB 1 ATOM 1251 C CG . GLU A 1 170 ? 35.593 57.179 -1.357 1.00 7.61 ? 170 GLU A CG 1 ATOM 1252 C CD . GLU A 1 170 ? 35.081 55.928 -0.677 1.00 8.26 ? 170 GLU A CD 1 ATOM 1253 O OE1 . GLU A 1 170 ? 34.317 55.162 -1.313 1.00 9.01 ? 170 GLU A OE1 1 ATOM 1254 O OE2 . GLU A 1 170 ? 35.453 55.698 0.520 1.00 9.25 ? 170 GLU A OE2 1 ATOM 1255 N N . ALA A 1 171 ? 34.168 60.385 -4.668 1.00 5.93 ? 171 ALA A N 1 ATOM 1256 C CA . ALA A 1 171 ? 33.429 60.788 -5.859 1.00 5.75 ? 171 ALA A CA 1 ATOM 1257 C C . ALA A 1 171 ? 34.299 61.529 -6.881 1.00 5.86 ? 171 ALA A C 1 ATOM 1258 O O . ALA A 1 171 ? 34.308 61.233 -8.065 1.00 7.15 ? 171 ALA A O 1 ATOM 1259 C CB . ALA A 1 171 ? 32.235 61.622 -5.492 1.00 6.89 ? 171 ALA A CB 1 ATOM 1260 N N . ASN A 1 172 ? 35.020 62.550 -6.403 1.00 5.75 ? 172 ASN A N 1 ATOM 1261 C CA . ASN A 1 172 ? 35.740 63.458 -7.301 1.00 6.11 ? 172 ASN A CA 1 ATOM 1262 C C . ASN A 1 172 ? 37.195 63.080 -7.477 1.00 5.63 ? 172 ASN A C 1 ATOM 1263 O O . ASN A 1 172 ? 37.871 63.540 -8.384 1.00 5.87 ? 172 ASN A O 1 ATOM 1264 C CB . ASN A 1 172 ? 35.709 64.873 -6.715 1.00 5.92 ? 172 ASN A CB 1 ATOM 1265 C CG . ASN A 1 172 ? 34.304 65.419 -6.596 1.00 8.34 ? 172 ASN A CG 1 ATOM 1266 O OD1 . ASN A 1 172 ? 33.621 65.620 -7.608 1.00 10.37 ? 172 ASN A OD1 1 ATOM 1267 N ND2 . ASN A 1 172 ? 33.873 65.703 -5.376 1.00 9.69 ? 172 ASN A ND2 1 ATOM 1268 N N . SER A 1 173 ? 37.708 62.275 -6.565 1.00 5.97 ? 173 SER A N 1 ATOM 1269 C CA . SER A 1 173 ? 39.151 61.930 -6.514 1.00 6.29 ? 173 SER A CA 1 ATOM 1270 C C . SER A 1 173 ? 39.523 61.038 -7.685 1.00 5.79 ? 173 SER A C 1 ATOM 1271 O O . SER A 1 173 ? 38.799 60.089 -8.045 1.00 6.68 ? 173 SER A O 1 ATOM 1272 C CB . SER A 1 173 ? 39.456 61.251 -5.188 1.00 6.13 ? 173 SER A CB 1 ATOM 1273 O OG . SER A 1 173 ? 38.558 60.141 -5.029 1.00 6.97 ? 173 SER A OG 1 ATOM 1274 N N . HIS A 1 174 ? 40.686 61.295 -8.255 1.00 5.46 ? 174 HIS A N 1 ATOM 1275 C CA . HIS A 1 174 ? 41.229 60.386 -9.242 1.00 5.18 ? 174 HIS A CA 1 ATOM 1276 C C . HIS A 1 174 ? 41.882 59.200 -8.542 1.00 4.55 ? 174 HIS A C 1 ATOM 1277 O O . HIS A 1 174 ? 42.539 59.376 -7.507 1.00 5.35 ? 174 HIS A O 1 ATOM 1278 C CB . HIS A 1 174 ? 42.264 61.104 -10.093 1.00 5.52 ? 174 HIS A CB 1 ATOM 1279 C CG . HIS A 1 174 ? 42.508 60.419 -11.384 1.00 5.96 ? 174 HIS A CG 1 ATOM 1280 N ND1 . HIS A 1 174 ? 43.254 59.266 -11.496 1.00 7.46 ? 174 HIS A ND1 1 ATOM 1281 C CD2 . HIS A 1 174 ? 42.041 60.709 -12.616 1.00 7.60 ? 174 HIS A CD2 1 ATOM 1282 C CE1 . HIS A 1 174 ? 43.244 58.877 -12.760 1.00 8.46 ? 174 HIS A CE1 1 ATOM 1283 N NE2 . HIS A 1 174 ? 42.500 59.726 -13.447 1.00 8.82 ? 174 HIS A NE2 1 ATOM 1284 N N . TRP A 1 175 ? 41.749 58.002 -9.094 1.00 5.10 ? 175 TRP A N 1 ATOM 1285 C CA . TRP A 1 175 ? 42.332 56.812 -8.469 1.00 5.26 ? 175 TRP A CA 1 ATOM 1286 C C . TRP A 1 175 ? 43.818 56.987 -8.230 1.00 5.36 ? 175 TRP A C 1 ATOM 1287 O O . TRP A 1 175 ? 44.356 56.479 -7.240 1.00 6.09 ? 175 TRP A O 1 ATOM 1288 C CB . TRP A 1 175 ? 42.050 55.545 -9.289 1.00 5.61 ? 175 TRP A CB 1 ATOM 1289 C CG . TRP A 1 175 ? 42.879 55.352 -10.529 1.00 6.02 ? 175 TRP A CG 1 ATOM 1290 C CD1 . TRP A 1 175 ? 42.556 55.726 -11.816 1.00 6.77 ? 175 TRP A CD1 1 ATOM 1291 C CD2 . TRP A 1 175 ? 44.171 54.725 -10.602 1.00 6.68 ? 175 TRP A CD2 1 ATOM 1292 N NE1 . TRP A 1 175 ? 43.580 55.344 -12.667 1.00 7.31 ? 175 TRP A NE1 1 ATOM 1293 C CE2 . TRP A 1 175 ? 44.570 54.732 -11.941 1.00 6.48 ? 175 TRP A CE2 1 ATOM 1294 C CE3 . TRP A 1 175 ? 45.033 54.143 -9.651 1.00 7.25 ? 175 TRP A CE3 1 ATOM 1295 C CZ2 . TRP A 1 175 ? 45.791 54.193 -12.377 1.00 7.71 ? 175 TRP A CZ2 1 ATOM 1296 C CZ3 . TRP A 1 175 ? 46.220 53.593 -10.083 1.00 8.11 ? 175 TRP A CZ3 1 ATOM 1297 C CH2 . TRP A 1 175 ? 46.603 53.657 -11.430 1.00 8.92 ? 175 TRP A CH2 1 ATOM 1298 N N . ARG A 1 176 ? 44.504 57.696 -9.127 1.00 5.71 ? 176 ARG A N 1 ATOM 1299 C CA . ARG A 1 176 ? 45.954 57.898 -8.936 1.00 6.49 ? 176 ARG A CA 1 ATOM 1300 C C . ARG A 1 176 ? 46.218 58.652 -7.645 1.00 5.79 ? 176 ARG A C 1 ATOM 1301 O O . ARG A 1 176 ? 47.234 58.384 -6.964 1.00 6.19 ? 176 ARG A O 1 ATOM 1302 C CB . ARG A 1 176 ? 46.541 58.652 -10.165 1.00 7.36 ? 176 ARG A CB 1 ATOM 1303 C CG . ARG A 1 176 ? 46.512 57.752 -11.410 1.00 8.54 ? 176 ARG A CG 1 ATOM 1304 C CD . ARG A 1 176 ? 46.542 58.492 -12.758 1.00 10.60 ? 176 ARG A CD 1 ATOM 1305 N NE . ARG A 1 176 ? 47.615 59.474 -12.823 1.00 11.22 ? 176 ARG A NE 1 ATOM 1306 C CZ . ARG A 1 176 ? 47.763 60.350 -13.838 1.00 11.08 ? 176 ARG A CZ 1 ATOM 1307 N NH1 . ARG A 1 176 ? 46.846 60.332 -14.829 1.00 11.84 ? 176 ARG A NH1 1 ATOM 1308 N NH2 . ARG A 1 176 ? 48.742 61.267 -13.794 1.00 12.42 ? 176 ARG A NH2 1 ATOM 1309 N N . ASN A 1 177 ? 45.374 59.605 -7.305 1.00 5.19 ? 177 ASN A N 1 ATOM 1310 C CA . ASN A 1 177 ? 45.582 60.378 -6.076 1.00 5.64 ? 177 ASN A CA 1 ATOM 1311 C C . ASN A 1 177 ? 45.058 59.660 -4.841 1.00 5.68 ? 177 ASN A C 1 ATOM 1312 O O . ASN A 1 177 ? 45.601 59.829 -3.724 1.00 5.93 ? 177 ASN A O 1 ATOM 1313 C CB . ASN A 1 177 ? 44.970 61.777 -6.203 1.00 6.46 ? 177 ASN A CB 1 ATOM 1314 C CG . ASN A 1 177 ? 45.665 62.610 -7.221 1.00 6.59 ? 177 ASN A CG 1 ATOM 1315 O OD1 . ASN A 1 177 ? 46.835 62.414 -7.530 1.00 7.63 ? 177 ASN A OD1 1 ATOM 1316 N ND2 . ASN A 1 177 ? 44.926 63.566 -7.761 1.00 9.75 ? 177 ASN A ND2 1 ATOM 1317 N N . VAL A 1 178 ? 44.092 58.790 -5.009 1.00 5.69 ? 178 VAL A N 1 ATOM 1318 C CA . VAL A 1 178 ? 43.692 57.928 -3.906 1.00 5.86 ? 178 VAL A CA 1 ATOM 1319 C C . VAL A 1 178 ? 44.861 57.017 -3.567 1.00 5.60 ? 178 VAL A C 1 ATOM 1320 O O . VAL A 1 178 ? 45.189 56.855 -2.370 1.00 6.30 ? 178 VAL A O 1 ATOM 1321 C CB . VAL A 1 178 ? 42.425 57.083 -4.257 1.00 6.13 ? 178 VAL A CB 1 ATOM 1322 C CG1 . VAL A 1 178 ? 42.131 56.076 -3.141 1.00 8.65 ? 178 VAL A CG1 1 ATOM 1323 C CG2 . VAL A 1 178 ? 41.193 57.995 -4.465 1.00 7.63 ? 178 VAL A CG2 1 ATOM 1324 N N . LEU A 1 179 ? 45.515 56.462 -4.569 1.00 5.57 ? 179 LEU A N 1 ATOM 1325 C CA . LEU A 1 179 ? 46.675 55.627 -4.305 1.00 6.28 ? 179 LEU A CA 1 ATOM 1326 C C . LEU A 1 179 ? 47.817 56.449 -3.730 1.00 6.38 ? 179 LEU A C 1 ATOM 1327 O O . LEU A 1 179 ? 48.507 55.982 -2.788 1.00 6.48 ? 179 LEU A O 1 ATOM 1328 C CB . LEU A 1 179 ? 47.108 54.928 -5.611 1.00 6.22 ? 179 LEU A CB 1 ATOM 1329 C CG . LEU A 1 179 ? 48.412 54.090 -5.471 1.00 6.55 ? 179 LEU A CG 1 ATOM 1330 C CD1 . LEU A 1 179 ? 48.305 53.000 -4.369 1.00 7.27 ? 179 LEU A CD1 1 ATOM 1331 C CD2 . LEU A 1 179 ? 48.801 53.504 -6.831 1.00 7.70 ? 179 LEU A CD2 1 ATOM 1332 N N . LEU A 1 180 ? 48.011 57.674 -4.212 1.00 5.93 ? 180 LEU A N 1 ATOM 1333 C CA . LEU A 1 180 ? 49.112 58.516 -3.736 1.00 6.20 ? 180 LEU A CA 1 ATOM 1334 C C . LEU A 1 180 ? 48.944 58.764 -2.247 1.00 5.86 ? 180 LEU A C 1 ATOM 1335 O O . LEU A 1 180 ? 49.917 58.583 -1.455 1.00 6.09 ? 180 LEU A O 1 ATOM 1336 C CB . LEU A 1 180 ? 49.099 59.840 -4.496 1.00 6.47 ? 180 LEU A CB 1 ATOM 1337 C CG . LEU A 1 180 ? 50.217 60.809 -4.136 1.00 7.87 ? 180 LEU A CG 1 ATOM 1338 C CD1 . LEU A 1 180 ? 51.478 60.335 -4.800 1.00 9.58 ? 180 LEU A CD1 1 ATOM 1339 C CD2 . LEU A 1 180 ? 49.883 62.208 -4.629 1.00 9.38 ? 180 LEU A CD2 1 ATOM 1340 N N . GLN A 1 181 ? 47.751 59.157 -1.833 1.00 5.65 ? 181 GLN A N 1 ATOM 1341 C CA . GLN A 1 181 ? 47.579 59.466 -0.409 1.00 5.93 ? 181 GLN A CA 1 ATOM 1342 C C . GLN A 1 181 ? 47.635 58.233 0.489 1.00 5.71 ? 181 GLN A C 1 ATOM 1343 O O . GLN A 1 181 ? 48.150 58.297 1.642 1.00 5.71 ? 181 GLN A O 1 ATOM 1344 C CB . GLN A 1 181 ? 46.320 60.304 -0.197 1.00 5.67 ? 181 GLN A CB 1 ATOM 1345 C CG . GLN A 1 181 ? 45.008 59.570 -0.406 1.00 6.22 ? 181 GLN A CG 1 ATOM 1346 C CD . GLN A 1 181 ? 44.604 58.650 0.732 1.00 6.23 ? 181 GLN A CD 1 ATOM 1347 O OE1 . GLN A 1 181 ? 44.856 58.960 1.928 1.00 7.67 ? 181 GLN A OE1 1 ATOM 1348 N NE2 . GLN A 1 181 ? 43.966 57.535 0.402 1.00 7.45 ? 181 GLN A NE2 1 ATOM 1349 N N . LEU A 1 182 ? 47.138 57.102 -0.017 1.00 5.92 ? 182 LEU A N 1 ATOM 1350 C CA . LEU A 1 182 ? 47.239 55.840 0.713 1.00 6.43 ? 182 LEU A CA 1 ATOM 1351 C C . LEU A 1 182 ? 48.693 55.502 0.912 1.00 5.93 ? 182 LEU A C 1 ATOM 1352 O O . LEU A 1 182 ? 49.121 55.125 2.007 1.00 6.32 ? 182 LEU A O 1 ATOM 1353 C CB . LEU A 1 182 ? 46.539 54.717 -0.039 1.00 6.29 ? 182 LEU A CB 1 ATOM 1354 C CG . LEU A 1 182 ? 46.581 53.362 0.652 1.00 6.53 ? 182 LEU A CG 1 ATOM 1355 C CD1 . LEU A 1 182 ? 45.847 53.314 1.975 1.00 9.30 ? 182 LEU A CD1 1 ATOM 1356 C CD2 . LEU A 1 182 ? 45.996 52.298 -0.281 1.00 8.94 ? 182 LEU A CD2 1 ATOM 1357 N N . THR A 1 183 ? 49.483 55.634 -0.144 1.00 6.20 ? 183 THR A N 1 ATOM 1358 C CA . THR A 1 183 ? 50.904 55.307 -0.089 1.00 6.34 ? 183 THR A CA 1 ATOM 1359 C C . THR A 1 183 ? 51.614 56.255 0.842 1.00 6.25 ? 183 THR A C 1 ATOM 1360 O O . THR A 1 183 ? 52.532 55.831 1.591 1.00 6.73 ? 183 THR A O 1 ATOM 1361 C CB . THR A 1 183 ? 51.508 55.366 -1.509 1.00 6.66 ? 183 THR A CB 1 ATOM 1362 O OG1 . THR A 1 183 ? 50.830 54.441 -2.370 1.00 7.19 ? 183 THR A OG1 1 ATOM 1363 C CG2 . THR A 1 183 ? 53.015 54.948 -1.493 1.00 8.31 ? 183 THR A CG2 1 ATOM 1364 N N . GLU A 1 184 ? 51.261 57.524 0.838 1.00 6.19 ? 184 GLU A N 1 ATOM 1365 C CA . GLU A 1 184 ? 51.970 58.485 1.685 1.00 7.45 ? 184 GLU A CA 1 ATOM 1366 C C . GLU A 1 184 ? 51.769 58.104 3.161 1.00 7.58 ? 184 GLU A C 1 ATOM 1367 O O . GLU A 1 184 ? 52.718 58.095 3.969 1.00 8.20 ? 184 GLU A O 1 ATOM 1368 C CB . GLU A 1 184 ? 51.427 59.890 1.450 1.00 8.27 ? 184 GLU A CB 1 ATOM 1369 C CG . GLU A 1 184 ? 52.322 61.025 1.931 1.00 9.78 ? 184 GLU A CG 1 ATOM 1370 C CD . GLU A 1 184 ? 53.703 61.063 1.264 1.00 10.16 ? 184 GLU A CD 1 ATOM 1371 O OE1 . GLU A 1 184 ? 53.883 60.657 0.112 1.00 12.16 ? 184 GLU A OE1 1 ATOM 1372 O OE2 . GLU A 1 184 ? 54.619 61.531 1.947 1.00 13.83 ? 184 GLU A OE2 1 ATOM 1373 N N . GLY A 1 185 ? 50.540 57.817 3.557 1.00 7.40 ? 185 GLY A N 1 ATOM 1374 C CA . GLY A 1 185 ? 50.272 57.452 4.944 1.00 7.03 ? 185 GLY A CA 1 ATOM 1375 C C . GLY A 1 185 ? 50.864 56.105 5.292 1.00 7.25 ? 185 GLY A C 1 ATOM 1376 O O . GLY A 1 185 ? 51.463 55.944 6.390 1.00 7.97 ? 185 GLY A O 1 ATOM 1377 N N . GLN A 1 186 ? 50.759 55.117 4.416 1.00 6.92 ? 186 GLN A N 1 ATOM 1378 C CA . GLN A 1 186 ? 51.219 53.774 4.789 1.00 7.40 ? 186 GLN A CA 1 ATOM 1379 C C . GLN A 1 186 ? 52.745 53.717 4.798 1.00 7.40 ? 186 GLN A C 1 ATOM 1380 O O . GLN A 1 186 ? 53.344 52.942 5.576 1.00 7.84 ? 186 GLN A O 1 ATOM 1381 C CB . GLN A 1 186 ? 50.661 52.682 3.869 1.00 6.88 ? 186 GLN A CB 1 ATOM 1382 C CG . GLN A 1 186 ? 49.136 52.513 4.137 1.00 8.76 ? 186 GLN A CG 1 ATOM 1383 C CD . GLN A 1 186 ? 48.718 51.104 3.912 1.00 9.89 ? 186 GLN A CD 1 ATOM 1384 O OE1 . GLN A 1 186 ? 49.345 50.433 3.119 1.00 12.83 ? 186 GLN A OE1 1 ATOM 1385 N NE2 . GLN A 1 186 ? 47.657 50.649 4.550 1.00 9.58 ? 186 GLN A NE2 1 ATOM 1386 N N . THR A 1 187 ? 53.402 54.458 3.896 1.00 7.41 ? 187 THR A N 1 ATOM 1387 C CA . THR A 1 187 ? 54.871 54.499 3.918 1.00 7.70 ? 187 THR A CA 1 ATOM 1388 C C . THR A 1 187 ? 55.354 55.105 5.235 1.00 8.59 ? 187 THR A C 1 ATOM 1389 O O . THR A 1 187 ? 56.304 54.564 5.850 1.00 9.24 ? 187 THR A O 1 ATOM 1390 C CB . THR A 1 187 ? 55.382 55.249 2.709 1.00 7.43 ? 187 THR A CB 1 ATOM 1391 O OG1 . THR A 1 187 ? 54.912 54.564 1.529 1.00 7.90 ? 187 THR A OG1 1 ATOM 1392 C CG2 . THR A 1 187 ? 56.949 55.213 2.663 1.00 9.00 ? 187 THR A CG2 1 ATOM 1393 N N . TRP A 1 188 ? 54.709 56.168 5.689 1.00 7.59 ? 188 TRP A N 1 ATOM 1394 C CA . TRP A 1 188 ? 55.015 56.777 6.981 1.00 8.18 ? 188 TRP A CA 1 ATOM 1395 C C . TRP A 1 188 ? 54.802 55.742 8.086 1.00 8.84 ? 188 TRP A C 1 ATOM 1396 O O . TRP A 1 188 ? 55.703 55.515 8.932 1.00 9.23 ? 188 TRP A O 1 ATOM 1397 C CB . TRP A 1 188 ? 54.132 58.026 7.223 1.00 9.11 ? 188 TRP A CB 1 ATOM 1398 C CG . TRP A 1 188 ? 54.610 58.768 8.414 1.00 9.27 ? 188 TRP A CG 1 ATOM 1399 C CD1 . TRP A 1 188 ? 55.498 59.797 8.412 1.00 11.29 ? 188 TRP A CD1 1 ATOM 1400 C CD2 . TRP A 1 188 ? 54.300 58.487 9.791 1.00 9.25 ? 188 TRP A CD2 1 ATOM 1401 N NE1 . TRP A 1 188 ? 55.769 60.199 9.701 1.00 11.15 ? 188 TRP A NE1 1 ATOM 1402 C CE2 . TRP A 1 188 ? 55.047 59.412 10.570 1.00 9.57 ? 188 TRP A CE2 1 ATOM 1403 C CE3 . TRP A 1 188 ? 53.470 57.565 10.441 1.00 9.45 ? 188 TRP A CE3 1 ATOM 1404 C CZ2 . TRP A 1 188 ? 55.020 59.415 11.982 1.00 11.09 ? 188 TRP A CZ2 1 ATOM 1405 C CZ3 . TRP A 1 188 ? 53.466 57.554 11.853 1.00 10.30 ? 188 TRP A CZ3 1 ATOM 1406 C CH2 . TRP A 1 188 ? 54.222 58.496 12.589 1.00 9.87 ? 188 TRP A CH2 1 ATOM 1407 N N . LEU A 1 189 ? 53.682 55.033 8.080 1.00 8.26 ? 189 LEU A N 1 ATOM 1408 C CA . LEU A 1 189 ? 53.412 54.037 9.136 1.00 8.27 ? 189 LEU A CA 1 ATOM 1409 C C . LEU A 1 189 ? 54.419 52.940 9.127 1.00 9.20 ? 189 LEU A C 1 ATOM 1410 O O . LEU A 1 189 ? 54.812 52.464 10.230 1.00 10.11 ? 189 LEU A O 1 ATOM 1411 C CB . LEU A 1 189 ? 52.000 53.435 9.032 1.00 8.68 ? 189 LEU A CB 1 ATOM 1412 C CG . LEU A 1 189 ? 50.862 54.331 9.468 1.00 8.08 ? 189 LEU A CG 1 ATOM 1413 C CD1 . LEU A 1 189 ? 49.524 53.628 9.111 1.00 9.49 ? 189 LEU A CD1 1 ATOM 1414 C CD2 . LEU A 1 189 ? 50.954 54.581 11.006 1.00 9.40 ? 189 LEU A CD2 1 ATOM 1415 N N . LYS A 1 190 ? 54.833 52.440 7.978 1.00 8.31 ? 190 LYS A N 1 ATOM 1416 C CA . LYS A 1 190 ? 55.790 51.349 7.940 1.00 10.29 ? 190 LYS A CA 1 ATOM 1417 C C . LYS A 1 190 ? 57.115 51.840 8.538 1.00 10.71 ? 190 LYS A C 1 ATOM 1418 O O . LYS A 1 190 ? 57.732 51.121 9.358 1.00 11.91 ? 190 LYS A O 1 ATOM 1419 C CB . LYS A 1 190 ? 55.995 50.811 6.526 1.00 11.59 ? 190 LYS A CB 1 ATOM 1420 C CG . LYS A 1 190 ? 56.943 49.631 6.514 1.00 14.14 ? 190 LYS A CG 1 ATOM 1421 C CD . LYS A 1 190 ? 57.058 48.992 5.163 1.00 20.91 ? 190 LYS A CD 1 ATOM 1422 C CE . LYS A 1 190 ? 57.923 47.735 5.228 1.00 25.14 ? 190 LYS A CE 1 ATOM 1423 N NZ . LYS A 1 190 ? 58.179 47.236 3.841 1.00 26.97 ? 190 LYS A NZ 1 ATOM 1424 N N . GLN A 1 191 ? 57.538 53.032 8.163 1.00 11.28 ? 191 GLN A N 1 ATOM 1425 C CA . GLN A 1 191 ? 58.845 53.543 8.583 1.00 14.52 ? 191 GLN A CA 1 ATOM 1426 C C . GLN A 1 191 ? 58.859 53.806 10.076 1.00 14.33 ? 191 GLN A C 1 ATOM 1427 O O . GLN A 1 191 ? 59.833 53.425 10.756 1.00 16.95 ? 191 GLN A O 1 ATOM 1428 C CB . GLN A 1 191 ? 59.191 54.821 7.826 1.00 14.45 ? 191 GLN A CB 1 ATOM 1429 C CG . GLN A 1 191 ? 60.544 55.430 8.214 1.00 20.03 ? 191 GLN A CG 1 ATOM 1430 C CD . GLN A 1 191 ? 60.946 56.579 7.286 1.00 20.44 ? 191 GLN A CD 1 ATOM 1431 O OE1 . GLN A 1 191 ? 60.233 56.901 6.320 1.00 28.38 ? 191 GLN A OE1 1 ATOM 1432 N NE2 . GLN A 1 191 ? 62.087 57.198 7.580 1.00 27.80 ? 191 GLN A NE2 1 ATOM 1433 N N . PHE A 1 192 ? 57.833 54.447 10.617 1.00 12.64 ? 192 PHE A N 1 ATOM 1434 C CA . PHE A 1 192 ? 57.891 54.929 11.997 1.00 12.33 ? 192 PHE A CA 1 ATOM 1435 C C . PHE A 1 192 ? 57.172 54.072 13.016 1.00 13.74 ? 192 PHE A C 1 ATOM 1436 O O . PHE A 1 192 ? 57.586 54.034 14.182 1.00 15.36 ? 192 PHE A O 1 ATOM 1437 C CB . PHE A 1 192 ? 57.427 56.373 12.075 1.00 12.36 ? 192 PHE A CB 1 ATOM 1438 C CG . PHE A 1 192 ? 58.325 57.316 11.333 1.00 12.65 ? 192 PHE A CG 1 ATOM 1439 C CD1 . PHE A 1 192 ? 59.574 57.672 11.881 1.00 14.12 ? 192 PHE A CD1 1 ATOM 1440 C CD2 . PHE A 1 192 ? 57.990 57.791 10.064 1.00 13.08 ? 192 PHE A CD2 1 ATOM 1441 C CE1 . PHE A 1 192 ? 60.448 58.524 11.185 1.00 14.95 ? 192 PHE A CE1 1 ATOM 1442 C CE2 . PHE A 1 192 ? 58.860 58.638 9.365 1.00 14.17 ? 192 PHE A CE2 1 ATOM 1443 C CZ . PHE A 1 192 ? 60.103 59.020 9.951 1.00 15.17 ? 192 PHE A CZ 1 ATOM 1444 N N . MET A 1 193 ? 56.142 53.337 12.604 1.00 12.21 ? 193 MET A N 1 ATOM 1445 C CA A MET A 1 193 ? 55.305 52.541 13.509 0.50 12.25 ? 193 MET A CA 1 ATOM 1446 C CA B MET A 1 193 ? 55.343 52.539 13.530 0.50 12.85 ? 193 MET A CA 1 ATOM 1447 C C . MET A 1 193 ? 55.452 51.047 13.242 1.00 12.66 ? 193 MET A C 1 ATOM 1448 O O . MET A 1 193 ? 54.910 50.220 14.015 1.00 14.01 ? 193 MET A O 1 ATOM 1449 C CB A MET A 1 193 ? 53.818 52.953 13.415 0.50 12.68 ? 193 MET A CB 1 ATOM 1450 C CB B MET A 1 193 ? 53.881 53.008 13.519 0.50 13.56 ? 193 MET A CB 1 ATOM 1451 C CG A MET A 1 193 ? 53.508 54.290 14.080 0.50 10.89 ? 193 MET A CG 1 ATOM 1452 C CG B MET A 1 193 ? 53.758 54.522 13.616 0.50 14.54 ? 193 MET A CG 1 ATOM 1453 S SD A MET A 1 193 ? 53.669 54.208 15.873 0.50 11.22 ? 193 MET A SD 1 ATOM 1454 S SD B MET A 1 193 ? 54.599 55.271 15.020 0.50 20.68 ? 193 MET A SD 1 ATOM 1455 C CE A MET A 1 193 ? 54.687 55.668 16.249 0.50 14.55 ? 193 MET A CE 1 ATOM 1456 C CE B MET A 1 193 ? 53.450 54.812 16.229 0.50 15.61 ? 193 MET A CE 1 ATOM 1457 N N . ASN A 1 194 ? 56.135 50.687 12.150 1.00 11.90 ? 194 ASN A N 1 ATOM 1458 C CA . ASN A 1 194 ? 56.287 49.292 11.753 1.00 13.59 ? 194 ASN A CA 1 ATOM 1459 C C . ASN A 1 194 ? 54.978 48.508 11.640 1.00 13.41 ? 194 ASN A C 1 ATOM 1460 O O . ASN A 1 194 ? 54.878 47.358 12.083 1.00 13.59 ? 194 ASN A O 1 ATOM 1461 C CB . ASN A 1 194 ? 57.211 48.572 12.759 1.00 14.03 ? 194 ASN A CB 1 ATOM 1462 C CG . ASN A 1 194 ? 57.721 47.254 12.218 1.00 17.53 ? 194 ASN A CG 1 ATOM 1463 O OD1 . ASN A 1 194 ? 57.898 47.093 11.013 1.00 18.94 ? 194 ASN A OD1 1 ATOM 1464 N ND2 . ASN A 1 194 ? 57.973 46.299 13.115 1.00 20.69 ? 194 ASN A ND2 1 ATOM 1465 N N . VAL A 1 195 ? 53.949 49.124 11.057 1.00 11.61 ? 195 VAL A N 1 ATOM 1466 C CA . VAL A 1 195 ? 52.673 48.438 10.849 1.00 12.05 ? 195 VAL A CA 1 ATOM 1467 C C . VAL A 1 195 ? 52.095 48.861 9.506 1.00 10.74 ? 195 VAL A C 1 ATOM 1468 O O . VAL A 1 195 ? 52.362 49.973 9.043 1.00 10.39 ? 195 VAL A O 1 ATOM 1469 C CB . VAL A 1 195 ? 51.632 48.804 11.940 1.00 12.54 ? 195 VAL A CB 1 ATOM 1470 C CG1 . VAL A 1 195 ? 51.976 48.242 13.341 1.00 16.88 ? 195 VAL A CG1 1 ATOM 1471 C CG2 . VAL A 1 195 ? 51.350 50.277 11.986 1.00 13.74 ? 195 VAL A CG2 1 ATOM 1472 N N . THR A 1 196 ? 51.316 47.966 8.917 1.00 10.13 ? 196 THR A N 1 ATOM 1473 C CA . THR A 1 196 ? 50.594 48.242 7.662 1.00 10.60 ? 196 THR A CA 1 ATOM 1474 C C . THR A 1 196 ? 49.162 47.745 7.847 1.00 10.42 ? 196 THR A C 1 ATOM 1475 O O . THR A 1 196 ? 48.939 46.535 7.913 1.00 10.80 ? 196 THR A O 1 ATOM 1476 C CB . THR A 1 196 ? 51.250 47.506 6.475 1.00 11.65 ? 196 THR A CB 1 ATOM 1477 O OG1 . THR A 1 196 ? 52.622 47.938 6.312 1.00 12.92 ? 196 THR A OG1 1 ATOM 1478 C CG2 . THR A 1 196 ? 50.540 47.848 5.172 1.00 13.62 ? 196 THR A CG2 1 ATOM 1479 N N . PRO A 1 197 ? 48.202 48.662 7.964 1.00 9.54 ? 197 PRO A N 1 ATOM 1480 C CA . PRO A 1 197 ? 46.802 48.280 8.140 1.00 8.85 ? 197 PRO A CA 1 ATOM 1481 C C . PRO A 1 197 ? 46.301 47.403 7.013 1.00 9.51 ? 197 PRO A C 1 ATOM 1482 O O . PRO A 1 197 ? 46.673 47.628 5.835 1.00 9.15 ? 197 PRO A O 1 ATOM 1483 C CB . PRO A 1 197 ? 46.077 49.633 8.104 1.00 9.67 ? 197 PRO A CB 1 ATOM 1484 C CG . PRO A 1 197 ? 47.123 50.619 8.612 1.00 10.13 ? 197 PRO A CG 1 ATOM 1485 C CD . PRO A 1 197 ? 48.402 50.117 8.062 1.00 10.05 ? 197 PRO A CD 1 ATOM 1486 N N . THR A 1 198 ? 45.439 46.440 7.347 1.00 8.20 ? 198 THR A N 1 ATOM 1487 C CA . THR A 1 198 ? 44.764 45.609 6.340 1.00 9.05 ? 198 THR A CA 1 ATOM 1488 C C . THR A 1 198 ? 43.256 45.740 6.449 1.00 7.49 ? 198 THR A C 1 ATOM 1489 O O . THR A 1 198 ? 42.536 45.028 5.724 1.00 7.75 ? 198 THR A O 1 ATOM 1490 C CB . THR A 1 198 ? 45.140 44.117 6.475 1.00 10.22 ? 198 THR A CB 1 ATOM 1491 O OG1 . THR A 1 198 ? 44.750 43.698 7.789 1.00 11.88 ? 198 THR A OG1 1 ATOM 1492 C CG2 . THR A 1 198 ? 46.657 43.911 6.351 1.00 12.09 ? 198 THR A CG2 1 ATOM 1493 N N . ALA A 1 199 ? 42.784 46.618 7.337 1.00 7.49 ? 199 ALA A N 1 ATOM 1494 C CA . ALA A 1 199 ? 41.349 46.946 7.455 1.00 7.55 ? 199 ALA A CA 1 ATOM 1495 C C . ALA A 1 199 ? 41.196 48.440 7.217 1.00 7.83 ? 199 ALA A C 1 ATOM 1496 O O . ALA A 1 199 ? 41.965 49.236 7.770 1.00 7.55 ? 199 ALA A O 1 ATOM 1497 C CB . ALA A 1 199 ? 40.843 46.590 8.882 1.00 8.57 ? 199 ALA A CB 1 ATOM 1498 N N . SER A 1 200 ? 40.228 48.803 6.395 1.00 7.92 ? 200 SER A N 1 ATOM 1499 C CA . SER A 1 200 ? 39.942 50.188 6.058 1.00 7.92 ? 200 SER A CA 1 ATOM 1500 C C . SER A 1 200 ? 38.690 50.674 6.767 1.00 7.48 ? 200 SER A C 1 ATOM 1501 O O . SER A 1 200 ? 37.720 49.901 6.923 1.00 8.23 ? 200 SER A O 1 ATOM 1502 C CB . SER A 1 200 ? 39.788 50.315 4.542 1.00 8.98 ? 200 SER A CB 1 ATOM 1503 O OG . SER A 1 200 ? 39.544 51.683 4.180 1.00 11.11 ? 200 SER A OG 1 ATOM 1504 N N . TRP A 1 201 ? 38.686 51.943 7.150 1.00 7.58 ? 201 TRP A N 1 ATOM 1505 C CA . TRP A 1 201 ? 37.581 52.617 7.857 1.00 7.37 ? 201 TRP A CA 1 ATOM 1506 C C . TRP A 1 201 ? 37.227 53.903 7.103 1.00 7.39 ? 201 TRP A C 1 ATOM 1507 O O . TRP A 1 201 ? 37.999 54.846 7.103 1.00 8.71 ? 201 TRP A O 1 ATOM 1508 C CB . TRP A 1 201 ? 38.110 52.952 9.263 1.00 7.59 ? 201 TRP A CB 1 ATOM 1509 C CG . TRP A 1 201 ? 37.300 53.753 10.243 1.00 7.80 ? 201 TRP A CG 1 ATOM 1510 C CD1 . TRP A 1 201 ? 37.455 55.065 10.535 1.00 8.46 ? 201 TRP A CD1 1 ATOM 1511 C CD2 . TRP A 1 201 ? 36.336 53.253 11.172 1.00 8.11 ? 201 TRP A CD2 1 ATOM 1512 N NE1 . TRP A 1 201 ? 36.627 55.428 11.549 1.00 8.63 ? 201 TRP A NE1 1 ATOM 1513 C CE2 . TRP A 1 201 ? 35.922 54.338 11.962 1.00 8.71 ? 201 TRP A CE2 1 ATOM 1514 C CE3 . TRP A 1 201 ? 35.776 52.000 11.403 1.00 8.89 ? 201 TRP A CE3 1 ATOM 1515 C CZ2 . TRP A 1 201 ? 34.966 54.216 12.958 1.00 8.65 ? 201 TRP A CZ2 1 ATOM 1516 C CZ3 . TRP A 1 201 ? 34.819 51.880 12.397 1.00 9.64 ? 201 TRP A CZ3 1 ATOM 1517 C CH2 . TRP A 1 201 ? 34.436 52.980 13.170 1.00 10.26 ? 201 TRP A CH2 1 ATOM 1518 N N . ALA A 1 202 ? 36.059 53.914 6.467 1.00 7.29 ? 202 ALA A N 1 ATOM 1519 C CA . ALA A 1 202 ? 35.619 55.090 5.690 1.00 7.50 ? 202 ALA A CA 1 ATOM 1520 C C . ALA A 1 202 ? 34.203 55.463 6.124 1.00 7.53 ? 202 ALA A C 1 ATOM 1521 O O . ALA A 1 202 ? 33.218 55.125 5.488 1.00 7.83 ? 202 ALA A O 1 ATOM 1522 C CB . ALA A 1 202 ? 35.712 54.832 4.191 1.00 8.27 ? 202 ALA A CB 1 ATOM 1523 N N . ILE A 1 203 ? 34.123 56.171 7.240 1.00 7.31 ? 203 ILE A N 1 ATOM 1524 C CA . ILE A 1 203 ? 32.842 56.490 7.850 1.00 8.03 ? 203 ILE A CA 1 ATOM 1525 C C . ILE A 1 203 ? 32.210 57.750 7.295 1.00 8.36 ? 203 ILE A C 1 ATOM 1526 O O . ILE A 1 203 ? 31.053 58.006 7.540 1.00 8.72 ? 203 ILE A O 1 ATOM 1527 C CB . ILE A 1 203 ? 32.936 56.551 9.392 1.00 8.07 ? 203 ILE A CB 1 ATOM 1528 C CG1 . ILE A 1 203 ? 34.042 57.517 9.847 1.00 8.73 ? 203 ILE A CG1 1 ATOM 1529 C CG2 . ILE A 1 203 ? 33.199 55.150 9.936 1.00 9.46 ? 203 ILE A CG2 1 ATOM 1530 C CD1 . ILE A 1 203 ? 33.997 57.897 11.325 1.00 8.92 ? 203 ILE A CD1 1 ATOM 1531 N N . ALA A 1 204 ? 32.982 58.523 6.541 1.00 7.49 ? 204 ALA A N 1 ATOM 1532 C CA . ALA A 1 204 ? 32.594 59.902 6.247 1.00 7.71 ? 204 ALA A CA 1 ATOM 1533 C C . ALA A 1 204 ? 32.436 60.366 4.785 1.00 7.26 ? 204 ALA A C 1 ATOM 1534 O O . ALA A 1 204 ? 31.748 61.338 4.563 1.00 8.79 ? 204 ALA A O 1 ATOM 1535 C CB . ALA A 1 204 ? 33.453 60.879 7.016 1.00 9.13 ? 204 ALA A CB 1 ATOM 1536 N N . PRO A 1 205 ? 33.067 59.719 3.804 1.00 7.22 ? 205 PRO A N 1 ATOM 1537 C CA . PRO A 1 205 ? 32.885 60.206 2.424 1.00 8.14 ? 205 PRO A CA 1 ATOM 1538 C C . PRO A 1 205 ? 31.431 60.158 1.980 1.00 8.09 ? 205 PRO A C 1 ATOM 1539 O O . PRO A 1 205 ? 30.680 59.336 2.491 1.00 8.00 ? 205 PRO A O 1 ATOM 1540 C CB . PRO A 1 205 ? 33.722 59.236 1.585 1.00 8.91 ? 205 PRO A CB 1 ATOM 1541 C CG . PRO A 1 205 ? 34.757 58.725 2.531 1.00 12.05 ? 205 PRO A CG 1 ATOM 1542 C CD . PRO A 1 205 ? 34.012 58.591 3.841 1.00 8.20 ? 205 PRO A CD 1 ATOM 1543 N N . PHE A 1 206 ? 31.036 61.047 1.064 1.00 7.05 ? 206 PHE A N 1 ATOM 1544 C CA . PHE A 1 206 ? 29.596 61.257 0.828 1.00 7.69 ? 206 PHE A CA 1 ATOM 1545 C C . PHE A 1 206 ? 29.125 60.333 -0.306 1.00 7.54 ? 206 PHE A C 1 ATOM 1546 O O . PHE A 1 206 ? 28.932 60.732 -1.471 1.00 7.69 ? 206 PHE A O 1 ATOM 1547 C CB . PHE A 1 206 ? 29.300 62.726 0.529 1.00 7.59 ? 206 PHE A CB 1 ATOM 1548 C CG . PHE A 1 206 ? 30.117 63.710 1.351 1.00 7.44 ? 206 PHE A CG 1 ATOM 1549 C CD1 . PHE A 1 206 ? 30.375 63.481 2.686 1.00 8.27 ? 206 PHE A CD1 1 ATOM 1550 C CD2 . PHE A 1 206 ? 30.647 64.860 0.745 1.00 7.19 ? 206 PHE A CD2 1 ATOM 1551 C CE1 . PHE A 1 206 ? 31.144 64.380 3.414 1.00 8.11 ? 206 PHE A CE1 1 ATOM 1552 C CE2 . PHE A 1 206 ? 31.422 65.756 1.475 1.00 7.55 ? 206 PHE A CE2 1 ATOM 1553 C CZ . PHE A 1 206 ? 31.642 65.525 2.799 1.00 7.33 ? 206 PHE A CZ 1 ATOM 1554 N N . GLY A 1 207 ? 28.970 59.064 0.040 1.00 7.16 ? 207 GLY A N 1 ATOM 1555 C CA . GLY A 1 207 ? 28.811 57.997 -0.937 1.00 6.97 ? 207 GLY A CA 1 ATOM 1556 C C . GLY A 1 207 ? 30.133 57.286 -1.175 1.00 6.99 ? 207 GLY A C 1 ATOM 1557 O O . GLY A 1 207 ? 31.224 57.837 -0.847 1.00 7.42 ? 207 GLY A O 1 ATOM 1558 N N . HIS A 1 208 ? 30.087 56.084 -1.751 1.00 6.69 ? 208 HIS A N 1 ATOM 1559 C CA . HIS A 1 208 ? 31.262 55.211 -1.816 1.00 6.49 ? 208 HIS A CA 1 ATOM 1560 C C . HIS A 1 208 ? 31.455 54.585 -3.175 1.00 6.55 ? 208 HIS A C 1 ATOM 1561 O O . HIS A 1 208 ? 30.474 54.256 -3.884 1.00 7.36 ? 208 HIS A O 1 ATOM 1562 C CB . HIS A 1 208 ? 31.152 54.101 -0.749 1.00 7.68 ? 208 HIS A CB 1 ATOM 1563 C CG . HIS A 1 208 ? 31.200 54.604 0.666 1.00 6.59 ? 208 HIS A CG 1 ATOM 1564 N ND1 . HIS A 1 208 ? 32.384 54.895 1.307 1.00 9.06 ? 208 HIS A ND1 1 ATOM 1565 C CD2 . HIS A 1 208 ? 30.204 54.904 1.534 1.00 8.60 ? 208 HIS A CD2 1 ATOM 1566 C CE1 . HIS A 1 208 ? 32.098 55.334 2.529 1.00 9.00 ? 208 HIS A CE1 1 ATOM 1567 N NE2 . HIS A 1 208 ? 30.794 55.350 2.694 1.00 10.56 ? 208 HIS A NE2 1 ATOM 1568 N N . SER A 1 209 ? 32.717 54.464 -3.569 1.00 6.77 ? 209 SER A N 1 ATOM 1569 C CA . SER A 1 209 ? 33.103 53.988 -4.879 1.00 6.02 ? 209 SER A CA 1 ATOM 1570 C C . SER A 1 209 ? 33.803 52.632 -4.816 1.00 6.62 ? 209 SER A C 1 ATOM 1571 O O . SER A 1 209 ? 34.641 52.405 -3.939 1.00 6.94 ? 209 SER A O 1 ATOM 1572 C CB . SER A 1 209 ? 34.110 54.979 -5.482 1.00 7.17 ? 209 SER A CB 1 ATOM 1573 O OG . SER A 1 209 ? 34.597 54.471 -6.702 1.00 6.70 ? 209 SER A OG 1 ATOM 1574 N N . PRO A 1 210 ? 33.570 51.739 -5.789 1.00 6.17 ? 210 PRO A N 1 ATOM 1575 C CA . PRO A 1 210 ? 34.292 50.461 -5.866 1.00 6.82 ? 210 PRO A CA 1 ATOM 1576 C C . PRO A 1 210 ? 35.756 50.650 -6.212 1.00 6.84 ? 210 PRO A C 1 ATOM 1577 O O . PRO A 1 210 ? 36.536 49.676 -6.141 1.00 6.84 ? 210 PRO A O 1 ATOM 1578 C CB . PRO A 1 210 ? 33.538 49.683 -6.963 1.00 7.56 ? 210 PRO A CB 1 ATOM 1579 C CG . PRO A 1 210 ? 32.994 50.786 -7.838 1.00 7.84 ? 210 PRO A CG 1 ATOM 1580 C CD . PRO A 1 210 ? 32.572 51.860 -6.869 1.00 6.56 ? 210 PRO A CD 1 ATOM 1581 N N . THR A 1 211 ? 36.177 51.872 -6.573 1.00 6.57 ? 211 THR A N 1 ATOM 1582 C CA . THR A 1 211 ? 37.605 52.093 -6.726 1.00 7.35 ? 211 THR A CA 1 ATOM 1583 C C . THR A 1 211 ? 38.357 51.849 -5.440 1.00 6.86 ? 211 THR A C 1 ATOM 1584 O O . THR A 1 211 ? 39.531 51.455 -5.492 1.00 7.35 ? 211 THR A O 1 ATOM 1585 C CB . THR A 1 211 ? 37.815 53.530 -7.211 1.00 7.35 ? 211 THR A CB 1 ATOM 1586 O OG1 . THR A 1 211 ? 37.280 53.575 -8.536 1.00 7.99 ? 211 THR A OG1 1 ATOM 1587 C CG2 . THR A 1 211 ? 39.325 53.902 -7.293 1.00 8.99 ? 211 THR A CG2 1 ATOM 1588 N N . MET A 1 212 ? 37.730 52.113 -4.305 1.00 5.92 ? 212 MET A N 1 ATOM 1589 C CA . MET A 1 212 ? 38.367 51.852 -3.029 1.00 6.95 ? 212 MET A CA 1 ATOM 1590 C C . MET A 1 212 ? 38.730 50.373 -2.807 1.00 7.45 ? 212 MET A C 1 ATOM 1591 O O . MET A 1 212 ? 39.891 50.090 -2.608 1.00 7.07 ? 212 MET A O 1 ATOM 1592 C CB . MET A 1 212 ? 37.540 52.425 -1.886 1.00 7.76 ? 212 MET A CB 1 ATOM 1593 C CG . MET A 1 212 ? 37.304 53.927 -2.001 1.00 10.13 ? 212 MET A CG 1 ATOM 1594 S SD . MET A 1 212 ? 38.823 54.911 -2.223 1.00 13.41 ? 212 MET A SD 1 ATOM 1595 C CE . MET A 1 212 ? 39.580 54.785 -0.630 1.00 14.48 ? 212 MET A CE 1 ATOM 1596 N N . PRO A 1 213 ? 37.782 49.433 -2.853 1.00 7.15 ? 213 PRO A N 1 ATOM 1597 C CA . PRO A 1 213 ? 38.204 48.028 -2.701 1.00 7.04 ? 213 PRO A CA 1 ATOM 1598 C C . PRO A 1 213 ? 39.162 47.631 -3.815 1.00 7.19 ? 213 PRO A C 1 ATOM 1599 O O . PRO A 1 213 ? 40.043 46.790 -3.575 1.00 7.84 ? 213 PRO A O 1 ATOM 1600 C CB . PRO A 1 213 ? 36.878 47.222 -2.770 1.00 8.38 ? 213 PRO A CB 1 ATOM 1601 C CG . PRO A 1 213 ? 35.854 48.195 -3.382 1.00 7.62 ? 213 PRO A CG 1 ATOM 1602 C CD . PRO A 1 213 ? 36.298 49.566 -2.884 1.00 7.25 ? 213 PRO A CD 1 ATOM 1603 N N . TYR A 1 214 ? 39.050 48.186 -5.032 1.00 7.45 ? 214 TYR A N 1 ATOM 1604 C CA . TYR A 1 214 ? 40.003 47.833 -6.095 1.00 7.49 ? 214 TYR A CA 1 ATOM 1605 C C . TYR A 1 214 ? 41.436 48.117 -5.643 1.00 7.80 ? 214 TYR A C 1 ATOM 1606 O O . TYR A 1 214 ? 42.314 47.241 -5.719 1.00 7.94 ? 214 TYR A O 1 ATOM 1607 C CB . TYR A 1 214 ? 39.702 48.657 -7.336 1.00 8.19 ? 214 TYR A CB 1 ATOM 1608 C CG . TYR A 1 214 ? 40.621 48.446 -8.518 1.00 8.72 ? 214 TYR A CG 1 ATOM 1609 C CD1 . TYR A 1 214 ? 40.334 47.451 -9.454 1.00 14.82 ? 214 TYR A CD1 1 ATOM 1610 C CD2 . TYR A 1 214 ? 41.722 49.261 -8.739 1.00 9.11 ? 214 TYR A CD2 1 ATOM 1611 C CE1 . TYR A 1 214 ? 41.158 47.265 -10.586 1.00 14.77 ? 214 TYR A CE1 1 ATOM 1612 C CE2 . TYR A 1 214 ? 42.535 49.082 -9.845 1.00 9.64 ? 214 TYR A CE2 1 ATOM 1613 C CZ . TYR A 1 214 ? 42.221 48.113 -10.770 1.00 12.08 ? 214 TYR A CZ 1 ATOM 1614 O OH . TYR A 1 214 ? 42.996 47.932 -11.895 1.00 13.11 ? 214 TYR A OH 1 ATOM 1615 N N . ILE A 1 215 ? 41.686 49.344 -5.189 1.00 6.97 ? 215 ILE A N 1 ATOM 1616 C CA . ILE A 1 215 ? 43.034 49.759 -4.781 1.00 6.64 ? 215 ILE A CA 1 ATOM 1617 C C . ILE A 1 215 ? 43.436 49.029 -3.485 1.00 7.35 ? 215 ILE A C 1 ATOM 1618 O O . ILE A 1 215 ? 44.562 48.538 -3.347 1.00 7.93 ? 215 ILE A O 1 ATOM 1619 C CB . ILE A 1 215 ? 43.102 51.270 -4.578 1.00 7.72 ? 215 ILE A CB 1 ATOM 1620 C CG1 . ILE A 1 215 ? 42.932 52.011 -5.909 1.00 8.15 ? 215 ILE A CG1 1 ATOM 1621 C CG2 . ILE A 1 215 ? 44.422 51.666 -3.843 1.00 8.31 ? 215 ILE A CG2 1 ATOM 1622 C CD1 . ILE A 1 215 ? 42.789 53.520 -5.742 1.00 11.13 ? 215 ILE A CD1 1 ATOM 1623 N N . LEU A 1 216 ? 42.512 48.951 -2.528 1.00 6.46 ? 216 LEU A N 1 ATOM 1624 C CA . LEU A 1 216 ? 42.836 48.340 -1.240 1.00 6.68 ? 216 LEU A CA 1 ATOM 1625 C C . LEU A 1 216 ? 43.170 46.862 -1.392 1.00 7.28 ? 216 LEU A C 1 ATOM 1626 O O . LEU A 1 216 ? 44.172 46.423 -0.802 1.00 7.36 ? 216 LEU A O 1 ATOM 1627 C CB . LEU A 1 216 ? 41.682 48.518 -0.270 1.00 6.42 ? 216 LEU A CB 1 ATOM 1628 C CG . LEU A 1 216 ? 41.300 49.932 0.146 1.00 7.09 ? 216 LEU A CG 1 ATOM 1629 C CD1 . LEU A 1 216 ? 40.017 49.907 0.893 1.00 8.62 ? 216 LEU A CD1 1 ATOM 1630 C CD2 . LEU A 1 216 ? 42.427 50.580 0.991 1.00 9.15 ? 216 LEU A CD2 1 ATOM 1631 N N . GLN A 1 217 ? 42.406 46.107 -2.170 1.00 7.69 ? 217 GLN A N 1 ATOM 1632 C CA . GLN A 1 217 ? 42.687 44.688 -2.323 1.00 8.45 ? 217 GLN A CA 1 ATOM 1633 C C . GLN A 1 217 ? 44.056 44.465 -3.005 1.00 8.98 ? 217 GLN A C 1 ATOM 1634 O O . GLN A 1 217 ? 44.711 43.457 -2.724 1.00 11.07 ? 217 GLN A O 1 ATOM 1635 C CB . GLN A 1 217 ? 41.506 44.065 -3.059 1.00 9.98 ? 217 GLN A CB 1 ATOM 1636 C CG . GLN A 1 217 ? 41.549 42.539 -3.086 1.00 10.92 ? 217 GLN A CG 1 ATOM 1637 C CD . GLN A 1 217 ? 42.376 41.971 -4.226 1.00 16.28 ? 217 GLN A CD 1 ATOM 1638 O OE1 . GLN A 1 217 ? 42.510 42.599 -5.279 1.00 16.27 ? 217 GLN A OE1 1 ATOM 1639 N NE2 . GLN A 1 217 ? 42.908 40.746 -4.034 1.00 16.95 ? 217 GLN A NE2 1 ATOM 1640 N N . LYS A 1 218 ? 44.519 45.391 -3.847 1.00 7.93 ? 218 LYS A N 1 ATOM 1641 C CA . LYS A 1 218 ? 45.834 45.287 -4.484 1.00 7.79 ? 218 LYS A CA 1 ATOM 1642 C C . LYS A 1 218 ? 46.935 45.912 -3.623 1.00 7.61 ? 218 LYS A C 1 ATOM 1643 O O . LYS A 1 218 ? 48.095 45.983 -4.044 1.00 7.92 ? 218 LYS A O 1 ATOM 1644 C CB . LYS A 1 218 ? 45.746 46.006 -5.824 1.00 8.40 ? 218 LYS A CB 1 ATOM 1645 C CG . LYS A 1 218 ? 44.940 45.204 -6.855 1.00 9.74 ? 218 LYS A CG 1 ATOM 1646 C CD . LYS A 1 218 ? 44.705 46.042 -8.138 1.00 9.50 ? 218 LYS A CD 1 ATOM 1647 C CE . LYS A 1 218 ? 44.264 45.226 -9.332 1.00 14.67 ? 218 LYS A CE 1 ATOM 1648 N NZ . LYS A 1 218 ? 43.133 44.288 -9.124 1.00 14.95 ? 218 LYS A NZ 1 ATOM 1649 N N . SER A 1 219 ? 46.574 46.372 -2.432 1.00 7.31 ? 219 SER A N 1 ATOM 1650 C CA . SER A 1 219 ? 47.481 46.972 -1.457 1.00 7.58 ? 219 SER A CA 1 ATOM 1651 C C . SER A 1 219 ? 47.489 46.188 -0.136 1.00 7.64 ? 219 SER A C 1 ATOM 1652 O O . SER A 1 219 ? 47.853 46.729 0.895 1.00 8.78 ? 219 SER A O 1 ATOM 1653 C CB . SER A 1 219 ? 47.136 48.449 -1.195 1.00 8.20 ? 219 SER A CB 1 ATOM 1654 O OG . SER A 1 219 ? 47.132 49.160 -2.441 1.00 8.30 ? 219 SER A OG 1 ATOM 1655 N N . GLY A 1 220 ? 47.132 44.904 -0.209 1.00 8.04 ? 220 GLY A N 1 ATOM 1656 C CA . GLY A 1 220 ? 47.234 43.975 0.921 1.00 9.63 ? 220 GLY A CA 1 ATOM 1657 C C . GLY A 1 220 ? 46.026 43.944 1.855 1.00 9.02 ? 220 GLY A C 1 ATOM 1658 O O . GLY A 1 220 ? 46.030 43.205 2.846 1.00 10.40 ? 220 GLY A O 1 ATOM 1659 N N . PHE A 1 221 ? 44.985 44.741 1.597 1.00 8.01 ? 221 PHE A N 1 ATOM 1660 C CA . PHE A 1 221 ? 43.836 44.768 2.516 1.00 7.75 ? 221 PHE A CA 1 ATOM 1661 C C . PHE A 1 221 ? 43.012 43.508 2.438 1.00 8.32 ? 221 PHE A C 1 ATOM 1662 O O . PHE A 1 221 ? 42.909 42.873 1.377 1.00 9.05 ? 221 PHE A O 1 ATOM 1663 C CB . PHE A 1 221 ? 42.933 45.998 2.281 1.00 7.66 ? 221 PHE A CB 1 ATOM 1664 C CG . PHE A 1 221 ? 43.521 47.265 2.814 1.00 6.88 ? 221 PHE A CG 1 ATOM 1665 C CD1 . PHE A 1 221 ? 44.622 47.876 2.212 1.00 7.60 ? 221 PHE A CD1 1 ATOM 1666 C CD2 . PHE A 1 221 ? 42.937 47.869 3.927 1.00 7.15 ? 221 PHE A CD2 1 ATOM 1667 C CE1 . PHE A 1 221 ? 45.149 49.043 2.742 1.00 6.96 ? 221 PHE A CE1 1 ATOM 1668 C CE2 . PHE A 1 221 ? 43.442 49.020 4.444 1.00 7.11 ? 221 PHE A CE2 1 ATOM 1669 C CZ . PHE A 1 221 ? 44.548 49.635 3.859 1.00 7.44 ? 221 PHE A CZ 1 ATOM 1670 N N . LYS A 1 222 ? 42.350 43.233 3.553 1.00 8.56 ? 222 LYS A N 1 ATOM 1671 C CA . LYS A 1 222 ? 41.475 42.081 3.665 1.00 9.29 ? 222 LYS A CA 1 ATOM 1672 C C . LYS A 1 222 ? 40.062 42.484 4.041 1.00 9.05 ? 222 LYS A C 1 ATOM 1673 O O . LYS A 1 222 ? 39.159 41.688 3.870 1.00 9.36 ? 222 LYS A O 1 ATOM 1674 C CB . LYS A 1 222 ? 41.998 41.088 4.713 1.00 11.96 ? 222 LYS A CB 1 ATOM 1675 C CG . LYS A 1 222 ? 43.419 40.625 4.502 1.00 14.81 ? 222 LYS A CG 1 ATOM 1676 C CD . LYS A 1 222 ? 43.650 39.901 3.219 1.00 21.33 ? 222 LYS A CD 1 ATOM 1677 C CE . LYS A 1 222 ? 45.030 39.251 3.277 1.00 26.17 ? 222 LYS A CE 1 ATOM 1678 N NZ . LYS A 1 222 ? 45.284 38.364 2.123 1.00 30.30 ? 222 LYS A NZ 1 ATOM 1679 N N . ASN A 1 223 ? 39.844 43.696 4.549 1.00 7.26 ? 223 ASN A N 1 ATOM 1680 C CA . ASN A 1 223 ? 38.510 44.112 5.011 1.00 7.97 ? 223 ASN A CA 1 ATOM 1681 C C . ASN A 1 223 ? 38.340 45.608 4.871 1.00 7.12 ? 223 ASN A C 1 ATOM 1682 O O . ASN A 1 223 ? 39.292 46.347 4.982 1.00 7.26 ? 223 ASN A O 1 ATOM 1683 C CB . ASN A 1 223 ? 38.300 43.747 6.486 1.00 8.56 ? 223 ASN A CB 1 ATOM 1684 C CG . ASN A 1 223 ? 38.294 42.250 6.732 1.00 9.93 ? 223 ASN A CG 1 ATOM 1685 O OD1 . ASN A 1 223 ? 37.318 41.581 6.452 1.00 12.03 ? 223 ASN A OD1 1 ATOM 1686 N ND2 . ASN A 1 223 ? 39.388 41.736 7.250 1.00 8.37 ? 223 ASN A ND2 1 ATOM 1687 N N . MET A 1 224 ? 37.106 46.040 4.679 1.00 6.99 ? 224 MET A N 1 ATOM 1688 C CA . MET A 1 224 ? 36.812 47.476 4.695 1.00 7.25 ? 224 MET A CA 1 ATOM 1689 C C . MET A 1 224 ? 35.428 47.777 5.239 1.00 7.44 ? 224 MET A C 1 ATOM 1690 O O . MET A 1 224 ? 34.556 46.922 5.219 1.00 7.90 ? 224 MET A O 1 ATOM 1691 C CB . MET A 1 224 ? 36.966 48.069 3.295 1.00 8.76 ? 224 MET A CB 1 ATOM 1692 C CG . MET A 1 224 ? 35.958 47.533 2.283 1.00 8.71 ? 224 MET A CG 1 ATOM 1693 S SD . MET A 1 224 ? 36.139 48.368 0.673 1.00 10.15 ? 224 MET A SD 1 ATOM 1694 C CE . MET A 1 224 ? 35.666 50.019 1.099 1.00 13.95 ? 224 MET A CE 1 ATOM 1695 N N . LEU A 1 225 ? 35.257 49.008 5.714 1.00 7.16 ? 225 LEU A N 1 ATOM 1696 C CA . LEU A 1 225 ? 34.006 49.439 6.334 1.00 7.15 ? 225 LEU A CA 1 ATOM 1697 C C . LEU A 1 225 ? 33.591 50.738 5.671 1.00 7.73 ? 225 LEU A C 1 ATOM 1698 O O . LEU A 1 225 ? 34.438 51.650 5.464 1.00 7.32 ? 225 LEU A O 1 ATOM 1699 C CB . LEU A 1 225 ? 34.188 49.632 7.838 1.00 7.86 ? 225 LEU A CB 1 ATOM 1700 C CG . LEU A 1 225 ? 32.979 50.191 8.584 1.00 8.28 ? 225 LEU A CG 1 ATOM 1701 C CD1 . LEU A 1 225 ? 32.892 49.581 10.003 1.00 9.30 ? 225 LEU A CD1 1 ATOM 1702 C CD2 . LEU A 1 225 ? 33.033 51.727 8.605 1.00 8.48 ? 225 LEU A CD2 1 ATOM 1703 N N . ILE A 1 226 ? 32.303 50.847 5.368 1.00 7.11 ? 226 ILE A N 1 ATOM 1704 C CA . ILE A 1 226 ? 31.709 52.079 4.820 1.00 8.18 ? 226 ILE A CA 1 ATOM 1705 C C . ILE A 1 226 ? 30.458 52.446 5.595 1.00 7.18 ? 226 ILE A C 1 ATOM 1706 O O . ILE A 1 226 ? 29.903 51.623 6.337 1.00 8.21 ? 226 ILE A O 1 ATOM 1707 C CB . ILE A 1 226 ? 31.395 51.882 3.296 1.00 7.98 ? 226 ILE A CB 1 ATOM 1708 C CG1 . ILE A 1 226 ? 30.338 50.792 3.100 1.00 8.20 ? 226 ILE A CG1 1 ATOM 1709 C CG2 . ILE A 1 226 ? 32.700 51.602 2.555 1.00 8.66 ? 226 ILE A CG2 1 ATOM 1710 C CD1 . ILE A 1 226 ? 29.907 50.607 1.606 1.00 9.64 ? 226 ILE A CD1 1 ATOM 1711 N N . GLN A 1 227 ? 29.991 53.680 5.431 1.00 8.06 ? 227 GLN A N 1 ATOM 1712 C CA . GLN A 1 227 ? 28.845 54.192 6.181 1.00 8.00 ? 227 GLN A CA 1 ATOM 1713 C C . GLN A 1 227 ? 27.882 55.036 5.367 1.00 8.79 ? 227 GLN A C 1 ATOM 1714 O O . GLN A 1 227 ? 26.674 54.910 5.586 1.00 9.08 ? 227 GLN A O 1 ATOM 1715 C CB . GLN A 1 227 ? 29.376 55.039 7.356 1.00 8.92 ? 227 GLN A CB 1 ATOM 1716 C CG . GLN A 1 227 ? 28.406 56.140 7.952 1.00 11.23 ? 227 GLN A CG 1 ATOM 1717 C CD . GLN A 1 227 ? 27.067 55.631 8.493 1.00 10.19 ? 227 GLN A CD 1 ATOM 1718 O OE1 . GLN A 1 227 ? 26.931 54.462 8.864 1.00 12.19 ? 227 GLN A OE1 1 ATOM 1719 N NE2 . GLN A 1 227 ? 26.093 56.515 8.530 1.00 11.49 ? 227 GLN A NE2 1 ATOM 1720 N N . ARG A 1 228 ? 28.334 55.955 4.532 1.00 8.64 ? 228 ARG A N 1 ATOM 1721 C CA A ARG A 1 228 ? 27.411 56.928 3.966 0.50 8.93 ? 228 ARG A CA 1 ATOM 1722 C CA B ARG A 1 228 ? 27.407 56.921 3.966 0.50 8.83 ? 228 ARG A CA 1 ATOM 1723 C C . ARG A 1 228 ? 26.847 56.400 2.673 1.00 8.92 ? 228 ARG A C 1 ATOM 1724 O O . ARG A 1 228 ? 27.354 56.671 1.590 1.00 9.10 ? 228 ARG A O 1 ATOM 1725 C CB A ARG A 1 228 ? 28.086 58.291 3.773 0.50 9.54 ? 228 ARG A CB 1 ATOM 1726 C CB B ARG A 1 228 ? 28.066 58.292 3.807 0.50 9.44 ? 228 ARG A CB 1 ATOM 1727 C CG A ARG A 1 228 ? 28.195 59.105 5.032 0.50 10.44 ? 228 ARG A CG 1 ATOM 1728 C CG B ARG A 1 228 ? 28.060 59.058 5.082 0.50 9.82 ? 228 ARG A CG 1 ATOM 1729 C CD A ARG A 1 228 ? 28.426 60.582 4.728 0.50 11.14 ? 228 ARG A CD 1 ATOM 1730 C CD B ARG A 1 228 ? 28.588 60.456 4.929 0.50 11.00 ? 228 ARG A CD 1 ATOM 1731 N NE A ARG A 1 228 ? 28.749 61.387 5.911 0.50 13.70 ? 228 ARG A NE 1 ATOM 1732 N NE B ARG A 1 228 ? 27.870 61.380 5.792 0.50 10.61 ? 228 ARG A NE 1 ATOM 1733 C CZ A ARG A 1 228 ? 27.863 62.083 6.614 0.50 14.15 ? 228 ARG A CZ 1 ATOM 1734 C CZ B ARG A 1 228 ? 28.434 62.394 6.418 0.50 10.63 ? 228 ARG A CZ 1 ATOM 1735 N NH1 A ARG A 1 228 ? 26.577 62.038 6.289 0.50 16.01 ? 228 ARG A NH1 1 ATOM 1736 N NH1 B ARG A 1 228 ? 29.736 62.599 6.301 0.50 9.30 ? 228 ARG A NH1 1 ATOM 1737 N NH2 A ARG A 1 228 ? 28.256 62.813 7.664 0.50 14.97 ? 228 ARG A NH2 1 ATOM 1738 N NH2 B ARG A 1 228 ? 27.690 63.201 7.174 0.50 10.03 ? 228 ARG A NH2 1 ATOM 1739 N N . THR A 1 229 ? 25.799 55.597 2.806 1.00 8.86 ? 229 THR A N 1 ATOM 1740 C CA . THR A 1 229 ? 25.047 55.103 1.681 1.00 8.46 ? 229 THR A CA 1 ATOM 1741 C C . THR A 1 229 ? 23.591 55.512 1.885 1.00 7.71 ? 229 THR A C 1 ATOM 1742 O O . THR A 1 229 ? 23.110 55.788 2.992 1.00 8.77 ? 229 THR A O 1 ATOM 1743 C CB . THR A 1 229 ? 25.145 53.583 1.531 1.00 8.81 ? 229 THR A CB 1 ATOM 1744 O OG1 . THR A 1 229 ? 24.577 52.997 2.713 1.00 9.94 ? 229 THR A OG1 1 ATOM 1745 C CG2 . THR A 1 229 ? 26.629 53.151 1.492 1.00 9.35 ? 229 THR A CG2 1 ATOM 1746 N N . HIS A 1 230 ? 22.907 55.575 0.756 1.00 8.26 ? 230 HIS A N 1 ATOM 1747 C CA . HIS A 1 230 ? 21.501 56.019 0.735 1.00 8.80 ? 230 HIS A CA 1 ATOM 1748 C C . HIS A 1 230 ? 20.675 55.272 1.771 1.00 8.72 ? 230 HIS A C 1 ATOM 1749 O O . HIS A 1 230 ? 20.771 54.044 1.879 1.00 9.11 ? 230 HIS A O 1 ATOM 1750 C CB . HIS A 1 230 ? 20.963 55.742 -0.665 1.00 8.69 ? 230 HIS A CB 1 ATOM 1751 C CG . HIS A 1 230 ? 19.654 56.417 -1.005 1.00 9.61 ? 230 HIS A CG 1 ATOM 1752 N ND1 . HIS A 1 230 ? 18.474 56.161 -0.330 1.00 9.72 ? 230 HIS A ND1 1 ATOM 1753 C CD2 . HIS A 1 230 ? 19.344 57.307 -1.977 1.00 11.38 ? 230 HIS A CD2 1 ATOM 1754 C CE1 . HIS A 1 230 ? 17.507 56.900 -0.848 1.00 10.43 ? 230 HIS A CE1 1 ATOM 1755 N NE2 . HIS A 1 230 ? 17.997 57.585 -1.866 1.00 9.74 ? 230 HIS A NE2 1 ATOM 1756 N N . TYR A 1 231 ? 19.845 56.006 2.518 1.00 8.91 ? 231 TYR A N 1 ATOM 1757 C CA . TYR A 1 231 ? 19.026 55.375 3.552 1.00 9.33 ? 231 TYR A CA 1 ATOM 1758 C C . TYR A 1 231 ? 18.146 54.234 3.024 1.00 9.71 ? 231 TYR A C 1 ATOM 1759 O O . TYR A 1 231 ? 17.900 53.261 3.741 1.00 9.87 ? 231 TYR A O 1 ATOM 1760 C CB . TYR A 1 231 ? 18.199 56.411 4.305 1.00 10.11 ? 231 TYR A CB 1 ATOM 1761 C CG . TYR A 1 231 ? 17.213 57.188 3.454 1.00 9.94 ? 231 TYR A CG 1 ATOM 1762 C CD1 . TYR A 1 231 ? 15.907 56.705 3.259 1.00 11.35 ? 231 TYR A CD1 1 ATOM 1763 C CD2 . TYR A 1 231 ? 17.565 58.409 2.840 1.00 9.98 ? 231 TYR A CD2 1 ATOM 1764 C CE1 . TYR A 1 231 ? 14.995 57.417 2.481 1.00 11.94 ? 231 TYR A CE1 1 ATOM 1765 C CE2 . TYR A 1 231 ? 16.668 59.123 2.061 1.00 11.29 ? 231 TYR A CE2 1 ATOM 1766 C CZ . TYR A 1 231 ? 15.366 58.621 1.883 1.00 10.73 ? 231 TYR A CZ 1 ATOM 1767 O OH . TYR A 1 231 ? 14.435 59.317 1.128 1.00 12.68 ? 231 TYR A OH 1 ATOM 1768 N N . SER A 1 232 ? 17.695 54.334 1.789 1.00 9.40 ? 232 SER A N 1 ATOM 1769 C CA . SER A 1 232 ? 16.878 53.251 1.221 1.00 10.89 ? 232 SER A CA 1 ATOM 1770 C C . SER A 1 232 ? 17.706 51.987 0.959 1.00 10.69 ? 232 SER A C 1 ATOM 1771 O O . SER A 1 232 ? 17.200 50.858 1.061 1.00 11.16 ? 232 SER A O 1 ATOM 1772 C CB . SER A 1 232 ? 16.200 53.691 -0.050 1.00 11.77 ? 232 SER A CB 1 ATOM 1773 O OG . SER A 1 232 ? 15.304 54.745 0.173 1.00 14.40 ? 232 SER A OG 1 ATOM 1774 N N . VAL A 1 233 ? 18.975 52.161 0.571 1.00 10.21 ? 233 VAL A N 1 ATOM 1775 C CA . VAL A 1 233 ? 19.889 51.041 0.392 1.00 10.43 ? 233 VAL A CA 1 ATOM 1776 C C . VAL A 1 233 ? 20.178 50.365 1.734 1.00 10.52 ? 233 VAL A C 1 ATOM 1777 O O . VAL A 1 233 ? 20.136 49.129 1.837 1.00 10.67 ? 233 VAL A O 1 ATOM 1778 C CB . VAL A 1 233 ? 21.202 51.514 -0.296 1.00 10.14 ? 233 VAL A CB 1 ATOM 1779 C CG1 . VAL A 1 233 ? 22.234 50.421 -0.283 1.00 10.56 ? 233 VAL A CG1 1 ATOM 1780 C CG2 . VAL A 1 233 ? 20.898 51.915 -1.737 1.00 11.40 ? 233 VAL A CG2 1 ATOM 1781 N N . LYS A 1 234 ? 20.446 51.164 2.754 1.00 9.42 ? 234 LYS A N 1 ATOM 1782 C CA . LYS A 1 234 ? 20.633 50.576 4.091 1.00 9.84 ? 234 LYS A CA 1 ATOM 1783 C C . LYS A 1 234 ? 19.420 49.699 4.473 1.00 10.77 ? 234 LYS A C 1 ATOM 1784 O O . LYS A 1 234 ? 19.586 48.574 4.949 1.00 10.64 ? 234 LYS A O 1 ATOM 1785 C CB . LYS A 1 234 ? 20.840 51.666 5.132 1.00 9.09 ? 234 LYS A CB 1 ATOM 1786 C CG . LYS A 1 234 ? 22.232 52.322 5.069 1.00 9.73 ? 234 LYS A CG 1 ATOM 1787 C CD . LYS A 1 234 ? 22.265 53.600 5.850 1.00 10.66 ? 234 LYS A CD 1 ATOM 1788 C CE . LYS A 1 234 ? 23.675 54.279 5.804 1.00 9.56 ? 234 LYS A CE 1 ATOM 1789 N NZ . LYS A 1 234 ? 24.550 53.706 6.894 1.00 9.79 ? 234 LYS A NZ 1 ATOM 1790 N N . LYS A 1 235 ? 18.211 50.229 4.289 1.00 10.24 ? 235 LYS A N 1 ATOM 1791 C CA . LYS A 1 235 ? 17.000 49.457 4.653 1.00 11.65 ? 235 LYS A CA 1 ATOM 1792 C C . LYS A 1 235 ? 16.904 48.173 3.851 1.00 11.08 ? 235 LYS A C 1 ATOM 1793 O O . LYS A 1 235 ? 16.668 47.089 4.432 1.00 11.80 ? 235 LYS A O 1 ATOM 1794 C CB . LYS A 1 235 ? 15.774 50.329 4.494 1.00 12.98 ? 235 LYS A CB 1 ATOM 1795 C CG . LYS A 1 235 ? 14.475 49.622 4.968 1.00 12.70 ? 235 LYS A CG 1 ATOM 1796 C CD . LYS A 1 235 ? 13.300 50.565 4.872 1.00 15.26 ? 235 LYS A CD 1 ATOM 1797 C CE . LYS A 1 235 ? 11.972 49.917 5.340 1.00 15.62 ? 235 LYS A CE 1 ATOM 1798 N NZ . LYS A 1 235 ? 10.838 50.877 5.186 1.00 23.60 ? 235 LYS A NZ 1 ATOM 1799 N N . GLU A 1 236 ? 17.087 48.251 2.543 1.00 10.68 ? 236 GLU A N 1 ATOM 1800 C CA . GLU A 1 236 ? 16.979 47.101 1.668 1.00 12.23 ? 236 GLU A CA 1 ATOM 1801 C C . GLU A 1 236 ? 17.995 46.016 2.015 1.00 12.39 ? 236 GLU A C 1 ATOM 1802 O O . GLU A 1 236 ? 17.674 44.834 2.121 1.00 13.05 ? 236 GLU A O 1 ATOM 1803 C CB . GLU A 1 236 ? 17.156 47.564 0.213 1.00 13.77 ? 236 GLU A CB 1 ATOM 1804 C CG . GLU A 1 236 ? 16.911 46.500 -0.860 1.00 18.66 ? 236 GLU A CG 1 ATOM 1805 C CD . GLU A 1 236 ? 15.425 46.170 -1.051 1.00 24.85 ? 236 GLU A CD 1 ATOM 1806 O OE1 . GLU A 1 236 ? 14.542 46.980 -0.660 1.00 28.19 ? 236 GLU A OE1 1 ATOM 1807 O OE2 . GLU A 1 236 ? 15.146 45.092 -1.607 1.00 29.58 ? 236 GLU A OE2 1 ATOM 1808 N N . LEU A 1 237 ? 19.256 46.398 2.171 1.00 11.12 ? 237 LEU A N 1 ATOM 1809 C CA . LEU A 1 237 ? 20.286 45.428 2.480 1.00 10.72 ? 237 LEU A CA 1 ATOM 1810 C C . LEU A 1 237 ? 20.094 44.906 3.906 1.00 10.27 ? 237 LEU A C 1 ATOM 1811 O O . LEU A 1 237 ? 20.325 43.711 4.153 1.00 10.99 ? 237 LEU A O 1 ATOM 1812 C CB . LEU A 1 237 ? 21.702 46.023 2.290 1.00 10.54 ? 237 LEU A CB 1 ATOM 1813 C CG . LEU A 1 237 ? 22.057 46.445 0.848 1.00 10.86 ? 237 LEU A CG 1 ATOM 1814 C CD1 . LEU A 1 237 ? 23.505 46.996 0.818 1.00 12.73 ? 237 LEU A CD1 1 ATOM 1815 C CD2 . LEU A 1 237 ? 21.953 45.318 -0.194 1.00 14.09 ? 237 LEU A CD2 1 ATOM 1816 N N . ALA A 1 238 ? 19.656 45.737 4.838 1.00 10.36 ? 238 ALA A N 1 ATOM 1817 C CA . ALA A 1 238 ? 19.466 45.249 6.214 1.00 11.43 ? 238 ALA A CA 1 ATOM 1818 C C . ALA A 1 238 ? 18.392 44.158 6.258 1.00 12.41 ? 238 ALA A C 1 ATOM 1819 O O . ALA A 1 238 ? 18.567 43.146 6.956 1.00 12.32 ? 238 ALA A O 1 ATOM 1820 C CB . ALA A 1 238 ? 19.077 46.381 7.111 1.00 11.21 ? 238 ALA A CB 1 ATOM 1821 N N . GLN A 1 239 ? 17.326 44.365 5.495 1.00 12.24 ? 239 GLN A N 1 ATOM 1822 C CA . GLN A 1 239 ? 16.221 43.399 5.464 1.00 14.77 ? 239 GLN A CA 1 ATOM 1823 C C . GLN A 1 239 ? 16.702 42.029 5.017 1.00 15.09 ? 239 GLN A C 1 ATOM 1824 O O . GLN A 1 239 ? 16.157 41.005 5.438 1.00 16.80 ? 239 GLN A O 1 ATOM 1825 C CB . GLN A 1 239 ? 15.111 43.936 4.564 1.00 14.61 ? 239 GLN A CB 1 ATOM 1826 C CG . GLN A 1 239 ? 14.286 45.005 5.240 1.00 17.67 ? 239 GLN A CG 1 ATOM 1827 C CD . GLN A 1 239 ? 13.266 45.697 4.337 1.00 19.21 ? 239 GLN A CD 1 ATOM 1828 O OE1 . GLN A 1 239 ? 13.360 45.668 3.105 1.00 23.83 ? 239 GLN A OE1 1 ATOM 1829 N NE2 . GLN A 1 239 ? 12.292 46.353 4.967 1.00 24.03 ? 239 GLN A NE2 1 ATOM 1830 N N . GLN A 1 240 ? 17.709 41.990 4.156 1.00 13.60 ? 240 GLN A N 1 ATOM 1831 C CA . GLN A 1 240 ? 18.219 40.755 3.587 1.00 13.95 ? 240 GLN A CA 1 ATOM 1832 C C . GLN A 1 240 ? 19.501 40.271 4.265 1.00 12.27 ? 240 GLN A C 1 ATOM 1833 O O . GLN A 1 240 ? 20.100 39.300 3.829 1.00 11.58 ? 240 GLN A O 1 ATOM 1834 C CB . GLN A 1 240 ? 18.462 40.927 2.074 1.00 15.01 ? 240 GLN A CB 1 ATOM 1835 C CG . GLN A 1 240 ? 17.248 41.407 1.280 1.00 18.32 ? 240 GLN A CG 1 ATOM 1836 C CD . GLN A 1 240 ? 16.094 40.445 1.399 1.00 21.33 ? 240 GLN A CD 1 ATOM 1837 O OE1 . GLN A 1 240 ? 16.291 39.227 1.356 1.00 24.90 ? 240 GLN A OE1 1 ATOM 1838 N NE2 . GLN A 1 240 ? 14.890 40.981 1.583 1.00 25.25 ? 240 GLN A NE2 1 ATOM 1839 N N . ARG A 1 241 ? 19.895 40.955 5.346 1.00 11.77 ? 241 ARG A N 1 ATOM 1840 C CA . ARG A 1 241 ? 21.204 40.729 5.967 1.00 11.22 ? 241 ARG A CA 1 ATOM 1841 C C . ARG A 1 241 ? 22.323 40.710 4.930 1.00 10.65 ? 241 ARG A C 1 ATOM 1842 O O . ARG A 1 241 ? 23.153 39.791 4.878 1.00 10.84 ? 241 ARG A O 1 ATOM 1843 C CB . ARG A 1 241 ? 21.225 39.440 6.810 1.00 11.43 ? 241 ARG A CB 1 ATOM 1844 C CG . ARG A 1 241 ? 20.226 39.513 7.918 1.00 14.26 ? 241 ARG A CG 1 ATOM 1845 C CD . ARG A 1 241 ? 20.288 38.370 8.915 1.00 17.79 ? 241 ARG A CD 1 ATOM 1846 N NE . ARG A 1 241 ? 20.309 37.071 8.274 1.00 23.64 ? 241 ARG A NE 1 ATOM 1847 C CZ . ARG A 1 241 ? 20.684 35.958 8.892 1.00 25.97 ? 241 ARG A CZ 1 ATOM 1848 N NH1 . ARG A 1 241 ? 21.071 36.000 10.157 1.00 26.30 ? 241 ARG A NH1 1 ATOM 1849 N NH2 . ARG A 1 241 ? 20.693 34.808 8.238 1.00 27.03 ? 241 ARG A NH2 1 ATOM 1850 N N . GLN A 1 242 ? 22.306 41.731 4.066 1.00 10.03 ? 242 GLN A N 1 ATOM 1851 C CA . GLN A 1 242 ? 23.342 41.904 3.034 1.00 10.33 ? 242 GLN A CA 1 ATOM 1852 C C . GLN A 1 242 ? 24.209 43.138 3.287 1.00 9.61 ? 242 GLN A C 1 ATOM 1853 O O . GLN A 1 242 ? 24.758 43.698 2.338 1.00 10.40 ? 242 GLN A O 1 ATOM 1854 C CB . GLN A 1 242 ? 22.706 41.949 1.647 1.00 9.90 ? 242 GLN A CB 1 ATOM 1855 C CG . GLN A 1 242 ? 22.061 40.615 1.243 1.00 11.91 ? 242 GLN A CG 1 ATOM 1856 C CD . GLN A 1 242 ? 21.213 40.742 -0.004 1.00 12.63 ? 242 GLN A CD 1 ATOM 1857 O OE1 . GLN A 1 242 ? 20.650 41.795 -0.282 1.00 13.14 ? 242 GLN A OE1 1 ATOM 1858 N NE2 . GLN A 1 242 ? 21.137 39.656 -0.759 1.00 14.51 ? 242 GLN A NE2 1 ATOM 1859 N N . LEU A 1 243 ? 24.325 43.537 4.551 1.00 8.64 ? 243 LEU A N 1 ATOM 1860 C CA . LEU A 1 243 ? 25.163 44.689 4.898 1.00 8.35 ? 243 LEU A CA 1 ATOM 1861 C C . LEU A 1 243 ? 26.629 44.315 4.955 1.00 9.62 ? 243 LEU A C 1 ATOM 1862 O O . LEU A 1 243 ? 27.486 45.208 4.936 1.00 9.58 ? 243 LEU A O 1 ATOM 1863 C CB . LEU A 1 243 ? 24.722 45.252 6.234 1.00 9.53 ? 243 LEU A CB 1 ATOM 1864 C CG . LEU A 1 243 ? 23.344 45.911 6.219 1.00 10.76 ? 243 LEU A CG 1 ATOM 1865 C CD1 . LEU A 1 243 ? 22.874 46.068 7.648 1.00 13.12 ? 243 LEU A CD1 1 ATOM 1866 C CD2 . LEU A 1 243 ? 23.336 47.295 5.516 1.00 12.80 ? 243 LEU A CD2 1 ATOM 1867 N N . GLU A 1 244 ? 26.946 43.027 5.056 1.00 9.01 ? 244 GLU A N 1 ATOM 1868 C CA . GLU A 1 244 ? 28.306 42.557 4.877 1.00 8.40 ? 244 GLU A CA 1 ATOM 1869 C C . GLU A 1 244 ? 28.355 41.760 3.595 1.00 8.45 ? 244 GLU A C 1 ATOM 1870 O O . GLU A 1 244 ? 27.503 40.875 3.379 1.00 9.23 ? 244 GLU A O 1 ATOM 1871 C CB . GLU A 1 244 ? 28.812 41.733 6.067 1.00 8.33 ? 244 GLU A CB 1 ATOM 1872 C CG . GLU A 1 244 ? 29.104 42.638 7.260 1.00 9.12 ? 244 GLU A CG 1 ATOM 1873 C CD . GLU A 1 244 ? 29.411 41.940 8.571 1.00 9.56 ? 244 GLU A CD 1 ATOM 1874 O OE1 . GLU A 1 244 ? 28.839 40.853 8.854 1.00 9.72 ? 244 GLU A OE1 1 ATOM 1875 O OE2 . GLU A 1 244 ? 30.227 42.508 9.339 1.00 10.04 ? 244 GLU A OE2 1 ATOM 1876 N N . PHE A 1 245 ? 29.336 42.034 2.749 1.00 8.06 ? 245 PHE A N 1 ATOM 1877 C CA . PHE A 1 245 ? 29.352 41.460 1.406 1.00 8.26 ? 245 PHE A CA 1 ATOM 1878 C C . PHE A 1 245 ? 30.754 41.419 0.853 1.00 7.91 ? 245 PHE A C 1 ATOM 1879 O O . PHE A 1 245 ? 31.617 42.205 1.304 1.00 8.61 ? 245 PHE A O 1 ATOM 1880 C CB . PHE A 1 245 ? 28.397 42.228 0.449 1.00 8.40 ? 245 PHE A CB 1 ATOM 1881 C CG . PHE A 1 245 ? 28.559 43.739 0.500 1.00 7.69 ? 245 PHE A CG 1 ATOM 1882 C CD1 . PHE A 1 245 ? 29.504 44.382 -0.282 1.00 8.17 ? 245 PHE A CD1 1 ATOM 1883 C CD2 . PHE A 1 245 ? 27.739 44.491 1.337 1.00 8.45 ? 245 PHE A CD2 1 ATOM 1884 C CE1 . PHE A 1 245 ? 29.632 45.783 -0.240 1.00 8.40 ? 245 PHE A CE1 1 ATOM 1885 C CE2 . PHE A 1 245 ? 27.889 45.872 1.417 1.00 8.56 ? 245 PHE A CE2 1 ATOM 1886 C CZ . PHE A 1 245 ? 28.830 46.515 0.595 1.00 8.19 ? 245 PHE A CZ 1 ATOM 1887 N N . LEU A 1 246 ? 30.975 40.560 -0.127 1.00 8.10 ? 246 LEU A N 1 ATOM 1888 C CA . LEU A 1 246 ? 32.226 40.499 -0.842 1.00 8.45 ? 246 LEU A CA 1 ATOM 1889 C C . LEU A 1 246 ? 32.080 41.401 -2.044 1.00 7.96 ? 246 LEU A C 1 ATOM 1890 O O . LEU A 1 246 ? 31.395 41.077 -3.023 1.00 8.16 ? 246 LEU A O 1 ATOM 1891 C CB . LEU A 1 246 ? 32.511 39.045 -1.259 1.00 9.59 ? 246 LEU A CB 1 ATOM 1892 C CG . LEU A 1 246 ? 32.882 38.149 -0.053 1.00 12.64 ? 246 LEU A CG 1 ATOM 1893 C CD1 . LEU A 1 246 ? 32.668 36.676 -0.424 1.00 16.45 ? 246 LEU A CD1 1 ATOM 1894 C CD2 . LEU A 1 246 ? 34.338 38.430 0.345 1.00 16.79 ? 246 LEU A CD2 1 ATOM 1895 N N . TRP A 1 247 ? 32.720 42.560 -1.947 1.00 7.77 ? 247 TRP A N 1 ATOM 1896 C CA . TRP A 1 247 ? 32.537 43.597 -2.965 1.00 7.25 ? 247 TRP A CA 1 ATOM 1897 C C . TRP A 1 247 ? 33.560 43.404 -4.070 1.00 7.28 ? 247 TRP A C 1 ATOM 1898 O O . TRP A 1 247 ? 34.768 43.591 -3.860 1.00 7.59 ? 247 TRP A O 1 ATOM 1899 C CB . TRP A 1 247 ? 32.731 44.957 -2.313 1.00 7.29 ? 247 TRP A CB 1 ATOM 1900 C CG . TRP A 1 247 ? 32.240 46.144 -3.155 1.00 7.10 ? 247 TRP A CG 1 ATOM 1901 C CD1 . TRP A 1 247 ? 31.734 46.140 -4.442 1.00 7.57 ? 247 TRP A CD1 1 ATOM 1902 C CD2 . TRP A 1 247 ? 32.261 47.514 -2.733 1.00 7.03 ? 247 TRP A CD2 1 ATOM 1903 N NE1 . TRP A 1 247 ? 31.404 47.432 -4.804 1.00 6.87 ? 247 TRP A NE1 1 ATOM 1904 C CE2 . TRP A 1 247 ? 31.720 48.290 -3.781 1.00 5.89 ? 247 TRP A CE2 1 ATOM 1905 C CE3 . TRP A 1 247 ? 32.679 48.166 -1.561 1.00 7.61 ? 247 TRP A CE3 1 ATOM 1906 C CZ2 . TRP A 1 247 ? 31.612 49.684 -3.696 1.00 8.43 ? 247 TRP A CZ2 1 ATOM 1907 C CZ3 . TRP A 1 247 ? 32.553 49.553 -1.480 1.00 6.99 ? 247 TRP A CZ3 1 ATOM 1908 C CH2 . TRP A 1 247 ? 32.035 50.293 -2.534 1.00 7.76 ? 247 TRP A CH2 1 ATOM 1909 N N . ARG A 1 248 ? 33.081 42.987 -5.244 1.00 7.60 ? 248 ARG A N 1 ATOM 1910 C CA . ARG A 1 248 ? 33.940 42.796 -6.409 1.00 8.16 ? 248 ARG A CA 1 ATOM 1911 C C . ARG A 1 248 ? 33.677 43.886 -7.455 1.00 7.83 ? 248 ARG A C 1 ATOM 1912 O O . ARG A 1 248 ? 32.645 44.548 -7.406 1.00 7.99 ? 248 ARG A O 1 ATOM 1913 C CB . ARG A 1 248 ? 33.715 41.424 -7.047 1.00 9.03 ? 248 ARG A CB 1 ATOM 1914 C CG . ARG A 1 248 ? 32.329 41.286 -7.702 1.00 8.79 ? 248 ARG A CG 1 ATOM 1915 C CD . ARG A 1 248 ? 32.226 39.993 -8.530 1.00 11.41 ? 248 ARG A CD 1 ATOM 1916 N NE . ARG A 1 248 ? 32.296 38.826 -7.641 1.00 13.12 ? 248 ARG A NE 1 ATOM 1917 C CZ . ARG A 1 248 ? 32.219 37.572 -8.085 1.00 13.55 ? 248 ARG A CZ 1 ATOM 1918 N NH1 . ARG A 1 248 ? 32.128 37.328 -9.388 1.00 14.12 ? 248 ARG A NH1 1 ATOM 1919 N NH2 . ARG A 1 248 ? 32.260 36.563 -7.228 1.00 14.10 ? 248 ARG A NH2 1 ATOM 1920 N N . GLN A 1 249 ? 34.607 44.025 -8.399 1.00 7.81 ? 249 GLN A N 1 ATOM 1921 C CA . GLN A 1 249 ? 34.421 45.009 -9.482 1.00 7.46 ? 249 GLN A CA 1 ATOM 1922 C C . GLN A 1 249 ? 33.326 44.569 -10.432 1.00 8.31 ? 249 GLN A C 1 ATOM 1923 O O . GLN A 1 249 ? 33.057 43.357 -10.583 1.00 8.95 ? 249 GLN A O 1 ATOM 1924 C CB . GLN A 1 249 ? 35.726 45.189 -10.239 1.00 8.56 ? 249 GLN A CB 1 ATOM 1925 C CG . GLN A 1 249 ? 36.840 45.682 -9.299 1.00 8.15 ? 249 GLN A CG 1 ATOM 1926 C CD . GLN A 1 249 ? 36.460 47.001 -8.627 1.00 8.74 ? 249 GLN A CD 1 ATOM 1927 O OE1 . GLN A 1 249 ? 36.150 47.990 -9.301 1.00 8.26 ? 249 GLN A OE1 1 ATOM 1928 N NE2 . GLN A 1 249 ? 36.457 47.030 -7.297 1.00 7.45 ? 249 GLN A NE2 1 ATOM 1929 N N . ILE A 1 250 ? 32.696 45.533 -11.094 1.00 8.29 ? 250 ILE A N 1 ATOM 1930 C CA . ILE A 1 250 ? 31.532 45.233 -11.918 1.00 9.24 ? 250 ILE A CA 1 ATOM 1931 C C . ILE A 1 250 ? 31.815 44.302 -13.102 1.00 9.51 ? 250 ILE A C 1 ATOM 1932 O O . ILE A 1 250 ? 30.883 43.675 -13.605 1.00 10.67 ? 250 ILE A O 1 ATOM 1933 C CB . ILE A 1 250 ? 30.847 46.549 -12.417 1.00 9.70 ? 250 ILE A CB 1 ATOM 1934 C CG1 . ILE A 1 250 ? 31.834 47.457 -13.174 1.00 10.96 ? 250 ILE A CG1 1 ATOM 1935 C CG2 . ILE A 1 250 ? 30.149 47.260 -11.279 1.00 10.88 ? 250 ILE A CG2 1 ATOM 1936 C CD1 . ILE A 1 250 ? 31.216 48.809 -13.649 1.00 12.31 ? 250 ILE A CD1 1 ATOM 1937 N N . TRP A 1 251 ? 33.066 44.241 -13.522 1.00 10.41 ? 251 TRP A N 1 ATOM 1938 C CA . TRP A 1 251 ? 33.416 43.388 -14.665 1.00 12.12 ? 251 TRP A CA 1 ATOM 1939 C C . TRP A 1 251 ? 33.999 42.052 -14.262 1.00 14.52 ? 251 TRP A C 1 ATOM 1940 O O . TRP A 1 251 ? 34.328 41.239 -15.121 1.00 15.06 ? 251 TRP A O 1 ATOM 1941 C CB . TRP A 1 251 ? 34.422 44.102 -15.564 1.00 13.45 ? 251 TRP A CB 1 ATOM 1942 C CG . TRP A 1 251 ? 35.674 44.254 -14.848 1.00 15.30 ? 251 TRP A CG 1 ATOM 1943 C CD1 . TRP A 1 251 ? 36.654 43.297 -14.675 1.00 17.67 ? 251 TRP A CD1 1 ATOM 1944 C CD2 . TRP A 1 251 ? 36.105 45.404 -14.140 1.00 14.94 ? 251 TRP A CD2 1 ATOM 1945 N NE1 . TRP A 1 251 ? 37.664 43.802 -13.905 1.00 16.45 ? 251 TRP A NE1 1 ATOM 1946 C CE2 . TRP A 1 251 ? 37.361 45.099 -13.565 1.00 14.60 ? 251 TRP A CE2 1 ATOM 1947 C CE3 . TRP A 1 251 ? 35.549 46.668 -13.907 1.00 14.19 ? 251 TRP A CE3 1 ATOM 1948 C CZ2 . TRP A 1 251 ? 38.071 46.001 -12.786 1.00 15.43 ? 251 TRP A CZ2 1 ATOM 1949 C CZ3 . TRP A 1 251 ? 36.261 47.570 -13.157 1.00 15.84 ? 251 TRP A CZ3 1 ATOM 1950 C CH2 . TRP A 1 251 ? 37.518 47.237 -12.610 1.00 16.08 ? 251 TRP A CH2 1 ATOM 1951 N N . ASP A 1 252 ? 34.163 41.833 -12.965 1.00 13.07 ? 252 ASP A N 1 ATOM 1952 C CA . ASP A 1 252 ? 34.950 40.708 -12.465 1.00 14.37 ? 252 ASP A CA 1 ATOM 1953 C C . ASP A 1 252 ? 34.127 39.434 -12.367 1.00 14.37 ? 252 ASP A C 1 ATOM 1954 O O . ASP A 1 252 ? 33.364 39.216 -11.445 1.00 14.48 ? 252 ASP A O 1 ATOM 1955 C CB . ASP A 1 252 ? 35.570 41.102 -11.115 1.00 13.91 ? 252 ASP A CB 1 ATOM 1956 C CG . ASP A 1 252 ? 36.305 39.972 -10.452 1.00 16.48 ? 252 ASP A CG 1 ATOM 1957 O OD1 . ASP A 1 252 ? 36.569 38.921 -11.097 1.00 18.53 ? 252 ASP A OD1 1 ATOM 1958 O OD2 . ASP A 1 252 ? 36.616 40.061 -9.248 1.00 14.38 ? 252 ASP A OD2 1 ATOM 1959 N N . ASN A 1 253 ? 34.279 38.575 -13.372 1.00 15.70 ? 253 ASN A N 1 ATOM 1960 C CA . ASN A 1 253 ? 33.489 37.356 -13.420 1.00 17.17 ? 253 ASN A CA 1 ATOM 1961 C C . ASN A 1 253 ? 33.905 36.316 -12.372 1.00 16.63 ? 253 ASN A C 1 ATOM 1962 O O . ASN A 1 253 ? 33.053 35.659 -11.783 1.00 17.52 ? 253 ASN A O 1 ATOM 1963 C CB . ASN A 1 253 ? 33.600 36.755 -14.814 1.00 18.10 ? 253 ASN A CB 1 ATOM 1964 C CG . ASN A 1 253 ? 32.750 35.555 -14.986 1.00 22.93 ? 253 ASN A CG 1 ATOM 1965 O OD1 . ASN A 1 253 ? 31.553 35.570 -14.683 1.00 25.66 ? 253 ASN A OD1 1 ATOM 1966 N ND2 . ASN A 1 253 ? 33.359 34.481 -15.491 1.00 24.82 ? 253 ASN A ND2 1 ATOM 1967 N N . LYS A 1 254 ? 35.202 36.233 -12.140 1.00 18.51 ? 254 LYS A N 1 ATOM 1968 C CA . LYS A 1 254 ? 35.779 35.193 -11.282 1.00 19.81 ? 254 LYS A CA 1 ATOM 1969 C C . LYS A 1 254 ? 35.682 35.548 -9.806 1.00 19.88 ? 254 LYS A C 1 ATOM 1970 O O . LYS A 1 254 ? 35.426 34.677 -8.963 1.00 21.02 ? 254 LYS A O 1 ATOM 1971 C CB . LYS A 1 254 ? 37.235 34.939 -11.675 1.00 21.67 ? 254 LYS A CB 1 ATOM 1972 C CG . LYS A 1 254 ? 37.915 33.780 -10.976 1.00 25.86 ? 254 LYS A CG 1 ATOM 1973 C CD . LYS A 1 254 ? 39.122 33.308 -11.801 1.00 29.72 ? 254 LYS A CD 1 ATOM 1974 C CE . LYS A 1 254 ? 40.270 32.809 -10.913 1.00 31.29 ? 254 LYS A CE 1 ATOM 1975 N NZ . LYS A 1 254 ? 39.832 31.999 -9.731 1.00 34.39 ? 254 LYS A NZ 1 ATOM 1976 N N . GLY A 1 255 ? 35.874 36.825 -9.487 1.00 18.68 ? 255 GLY A N 1 ATOM 1977 C CA . GLY A 1 255 ? 35.795 37.270 -8.103 1.00 16.96 ? 255 GLY A CA 1 ATOM 1978 C C . GLY A 1 255 ? 37.138 37.563 -7.457 1.00 16.19 ? 255 GLY A C 1 ATOM 1979 O O . GLY A 1 255 ? 37.181 37.824 -6.255 1.00 14.93 ? 255 GLY A O 1 ATOM 1980 N N . ASP A 1 256 ? 38.226 37.566 -8.213 1.00 16.34 ? 256 ASP A N 1 ATOM 1981 C CA . ASP A 1 256 ? 39.540 37.794 -7.597 1.00 17.57 ? 256 ASP A CA 1 ATOM 1982 C C . ASP A 1 256 ? 39.752 39.206 -7.043 1.00 15.78 ? 256 ASP A C 1 ATOM 1983 O O . ASP A 1 256 ? 40.638 39.428 -6.219 1.00 16.65 ? 256 ASP A O 1 ATOM 1984 C CB . ASP A 1 256 ? 40.676 37.456 -8.555 1.00 20.04 ? 256 ASP A CB 1 ATOM 1985 C CG . ASP A 1 256 ? 40.675 36.003 -8.984 1.00 25.42 ? 256 ASP A CG 1 ATOM 1986 O OD1 . ASP A 1 256 ? 40.126 35.144 -8.251 1.00 30.98 ? 256 ASP A OD1 1 ATOM 1987 O OD2 . ASP A 1 256 ? 41.225 35.647 -10.050 1.00 30.81 ? 256 ASP A OD2 1 ATOM 1988 N N . THR A 1 257 ? 38.906 40.149 -7.461 1.00 13.19 ? 257 THR A N 1 ATOM 1989 C CA . THR A 1 257 ? 38.993 41.513 -6.914 1.00 12.03 ? 257 THR A CA 1 ATOM 1990 C C . THR A 1 257 ? 38.235 41.695 -5.592 1.00 11.09 ? 257 THR A C 1 ATOM 1991 O O . THR A 1 257 ? 38.312 42.769 -4.975 1.00 11.30 ? 257 THR A O 1 ATOM 1992 C CB . THR A 1 257 ? 38.456 42.594 -7.895 1.00 12.05 ? 257 THR A CB 1 ATOM 1993 O OG1 . THR A 1 257 ? 37.048 42.399 -8.116 1.00 10.59 ? 257 THR A OG1 1 ATOM 1994 C CG2 . THR A 1 257 ? 39.211 42.528 -9.249 1.00 14.30 ? 257 THR A CG2 1 ATOM 1995 N N . ALA A 1 258 ? 37.504 40.668 -5.161 1.00 11.23 ? 258 ALA A N 1 ATOM 1996 C CA . ALA A 1 258 ? 36.566 40.795 -4.034 1.00 10.65 ? 258 ALA A CA 1 ATOM 1997 C C . ALA A 1 258 ? 37.256 41.220 -2.745 1.00 9.49 ? 258 ALA A C 1 ATOM 1998 O O . ALA A 1 258 ? 38.351 40.724 -2.417 1.00 10.91 ? 258 ALA A O 1 ATOM 1999 C CB . ALA A 1 258 ? 35.840 39.503 -3.784 1.00 11.84 ? 258 ALA A CB 1 ATOM 2000 N N . LEU A 1 259 ? 36.627 42.129 -2.028 1.00 8.59 ? 259 LEU A N 1 ATOM 2001 C CA . LEU A 1 259 ? 37.094 42.559 -0.704 1.00 8.31 ? 259 LEU A CA 1 ATOM 2002 C C . LEU A 1 259 ? 35.920 42.560 0.241 1.00 8.10 ? 259 LEU A C 1 ATOM 2003 O O . LEU A 1 259 ? 34.864 43.151 -0.034 1.00 7.88 ? 259 LEU A O 1 ATOM 2004 C CB . LEU A 1 259 ? 37.694 43.959 -0.761 1.00 8.36 ? 259 LEU A CB 1 ATOM 2005 C CG . LEU A 1 259 ? 38.468 44.365 0.503 1.00 8.15 ? 259 LEU A CG 1 ATOM 2006 C CD1 . LEU A 1 259 ? 39.699 43.490 0.743 1.00 9.93 ? 259 LEU A CD1 1 ATOM 2007 C CD2 . LEU A 1 259 ? 38.905 45.836 0.364 1.00 10.19 ? 259 LEU A CD2 1 ATOM 2008 N N . PHE A 1 260 ? 36.076 41.880 1.392 1.00 7.89 ? 260 PHE A N 1 ATOM 2009 C CA . PHE A 1 260 ? 34.995 41.849 2.373 1.00 8.03 ? 260 PHE A CA 1 ATOM 2010 C C . PHE A 1 260 ? 34.692 43.244 2.868 1.00 7.14 ? 260 PHE A C 1 ATOM 2011 O O . PHE A 1 260 ? 35.605 43.982 3.286 1.00 7.63 ? 260 PHE A O 1 ATOM 2012 C CB . PHE A 1 260 ? 35.407 40.964 3.563 1.00 8.73 ? 260 PHE A CB 1 ATOM 2013 C CG . PHE A 1 260 ? 34.309 40.804 4.574 1.00 8.14 ? 260 PHE A CG 1 ATOM 2014 C CD1 . PHE A 1 260 ? 33.322 39.824 4.399 1.00 10.23 ? 260 PHE A CD1 1 ATOM 2015 C CD2 . PHE A 1 260 ? 34.241 41.609 5.699 1.00 9.43 ? 260 PHE A CD2 1 ATOM 2016 C CE1 . PHE A 1 260 ? 32.294 39.670 5.343 1.00 12.17 ? 260 PHE A CE1 1 ATOM 2017 C CE2 . PHE A 1 260 ? 33.230 41.463 6.643 1.00 10.85 ? 260 PHE A CE2 1 ATOM 2018 C CZ . PHE A 1 260 ? 32.263 40.505 6.467 1.00 11.73 ? 260 PHE A CZ 1 ATOM 2019 N N . THR A 1 261 ? 33.411 43.617 2.847 1.00 6.89 ? 261 THR A N 1 ATOM 2020 C CA . THR A 1 261 ? 33.005 44.977 3.169 1.00 7.05 ? 261 THR A CA 1 ATOM 2021 C C . THR A 1 261 ? 31.883 44.931 4.198 1.00 7.24 ? 261 THR A C 1 ATOM 2022 O O . THR A 1 261 ? 30.926 44.146 4.035 1.00 8.31 ? 261 THR A O 1 ATOM 2023 C CB . THR A 1 261 ? 32.481 45.664 1.891 1.00 7.70 ? 261 THR A CB 1 ATOM 2024 O OG1 . THR A 1 261 ? 33.544 45.736 0.943 1.00 7.81 ? 261 THR A OG1 1 ATOM 2025 C CG2 . THR A 1 261 ? 32.042 47.093 2.178 1.00 8.81 ? 261 THR A CG2 1 ATOM 2026 N N . HIS A 1 262 ? 31.984 45.792 5.216 1.00 7.03 ? 262 HIS A N 1 ATOM 2027 C CA . HIS A 1 262 ? 30.926 45.981 6.199 1.00 7.10 ? 262 HIS A CA 1 ATOM 2028 C C . HIS A 1 262 ? 30.305 47.358 5.999 1.00 7.27 ? 262 HIS A C 1 ATOM 2029 O O . HIS A 1 262 ? 31.012 48.370 6.105 1.00 7.39 ? 262 HIS A O 1 ATOM 2030 C CB . HIS A 1 262 ? 31.546 45.886 7.617 1.00 8.54 ? 262 HIS A CB 1 ATOM 2031 C CG . HIS A 1 262 ? 30.601 46.257 8.719 1.00 7.63 ? 262 HIS A CG 1 ATOM 2032 N ND1 . HIS A 1 262 ? 29.985 45.321 9.519 1.00 8.68 ? 262 HIS A ND1 1 ATOM 2033 C CD2 . HIS A 1 262 ? 30.156 47.465 9.139 1.00 7.43 ? 262 HIS A CD2 1 ATOM 2034 C CE1 . HIS A 1 262 ? 29.234 45.947 10.420 1.00 9.33 ? 262 HIS A CE1 1 ATOM 2035 N NE2 . HIS A 1 262 ? 29.288 47.247 10.195 1.00 9.29 ? 262 HIS A NE2 1 ATOM 2036 N N . MET A 1 263 ? 29.016 47.398 5.682 1.00 7.35 ? 263 MET A N 1 ATOM 2037 C CA . MET A 1 263 ? 28.262 48.642 5.651 1.00 7.62 ? 263 MET A CA 1 ATOM 2038 C C . MET A 1 263 ? 27.541 48.846 6.971 1.00 8.19 ? 263 MET A C 1 ATOM 2039 O O . MET A 1 263 ? 26.783 47.953 7.405 1.00 8.81 ? 263 MET A O 1 ATOM 2040 C CB . MET A 1 263 ? 27.233 48.621 4.508 1.00 8.26 ? 263 MET A CB 1 ATOM 2041 C CG . MET A 1 263 ? 26.464 49.926 4.372 1.00 7.63 ? 263 MET A CG 1 ATOM 2042 S SD . MET A 1 263 ? 25.120 49.806 3.163 1.00 9.12 ? 263 MET A SD 1 ATOM 2043 C CE . MET A 1 263 ? 25.950 49.432 1.642 1.00 10.62 ? 263 MET A CE 1 ATOM 2044 N N A MET A 1 264 ? 27.758 49.989 7.624 0.50 7.69 ? 264 MET A N 1 ATOM 2045 N N B MET A 1 264 ? 27.753 49.983 7.630 0.50 7.97 ? 264 MET A N 1 ATOM 2046 C CA A MET A 1 264 ? 27.032 50.341 8.852 0.50 8.25 ? 264 MET A CA 1 ATOM 2047 C CA B MET A 1 264 ? 27.023 50.277 8.865 0.50 8.94 ? 264 MET A CA 1 ATOM 2048 C C A MET A 1 264 ? 25.570 50.611 8.490 0.50 8.60 ? 264 MET A C 1 ATOM 2049 C C B MET A 1 264 ? 25.577 50.622 8.506 0.50 8.94 ? 264 MET A C 1 ATOM 2050 O O A MET A 1 264 ? 25.276 51.025 7.361 0.50 8.85 ? 264 MET A O 1 ATOM 2051 O O B MET A 1 264 ? 25.302 51.094 7.401 0.50 9.30 ? 264 MET A O 1 ATOM 2052 C CB A MET A 1 264 ? 27.684 51.554 9.519 0.50 7.98 ? 264 MET A CB 1 ATOM 2053 C CB B MET A 1 264 ? 27.715 51.388 9.646 0.50 8.67 ? 264 MET A CB 1 ATOM 2054 C CG A MET A 1 264 ? 29.145 51.298 9.969 0.50 8.11 ? 264 MET A CG 1 ATOM 2055 C CG B MET A 1 264 ? 29.168 51.036 10.021 0.50 9.58 ? 264 MET A CG 1 ATOM 2056 S SD A MET A 1 264 ? 30.137 52.727 10.477 0.50 9.36 ? 264 MET A SD 1 ATOM 2057 S SD B MET A 1 264 ? 29.720 51.823 11.518 0.50 11.60 ? 264 MET A SD 1 ATOM 2058 C CE A MET A 1 264 ? 29.035 53.582 11.641 0.50 10.74 ? 264 MET A CE 1 ATOM 2059 C CE B MET A 1 264 ? 29.773 53.532 10.989 0.50 9.06 ? 264 MET A CE 1 ATOM 2060 N N . PRO A 1 265 ? 24.640 50.316 9.409 1.00 8.81 ? 265 PRO A N 1 ATOM 2061 C CA . PRO A 1 265 ? 23.215 50.319 9.040 1.00 9.73 ? 265 PRO A CA 1 ATOM 2062 C C . PRO A 1 265 ? 22.435 51.600 9.233 1.00 9.68 ? 265 PRO A C 1 ATOM 2063 O O . PRO A 1 265 ? 21.331 51.697 8.678 1.00 9.74 ? 265 PRO A O 1 ATOM 2064 C CB . PRO A 1 265 ? 22.613 49.238 9.962 1.00 10.81 ? 265 PRO A CB 1 ATOM 2065 C CG . PRO A 1 265 ? 23.471 49.191 11.152 1.00 10.91 ? 265 PRO A CG 1 ATOM 2066 C CD . PRO A 1 265 ? 24.852 49.790 10.788 1.00 9.04 ? 265 PRO A CD 1 ATOM 2067 N N . PHE A 1 266 ? 22.951 52.543 10.014 1.00 8.95 ? 266 PHE A N 1 ATOM 2068 C CA . PHE A 1 266 ? 22.153 53.655 10.514 1.00 9.32 ? 266 PHE A CA 1 ATOM 2069 C C . PHE A 1 266 ? 22.566 55.004 9.932 1.00 9.23 ? 266 PHE A C 1 ATOM 2070 O O . PHE A 1 266 ? 23.446 55.089 9.072 1.00 9.31 ? 266 PHE A O 1 ATOM 2071 C CB . PHE A 1 266 ? 22.118 53.653 12.042 1.00 9.80 ? 266 PHE A CB 1 ATOM 2072 C CG . PHE A 1 266 ? 21.600 52.333 12.645 1.00 9.70 ? 266 PHE A CG 1 ATOM 2073 C CD1 . PHE A 1 266 ? 20.457 51.700 12.139 1.00 10.54 ? 266 PHE A CD1 1 ATOM 2074 C CD2 . PHE A 1 266 ? 22.275 51.745 13.686 1.00 9.81 ? 266 PHE A CD2 1 ATOM 2075 C CE1 . PHE A 1 266 ? 19.980 50.496 12.705 1.00 10.29 ? 266 PHE A CE1 1 ATOM 2076 C CE2 . PHE A 1 266 ? 21.798 50.563 14.282 1.00 10.69 ? 266 PHE A CE2 1 ATOM 2077 C CZ . PHE A 1 266 ? 20.663 49.929 13.745 1.00 9.52 ? 266 PHE A CZ 1 ATOM 2078 N N . TYR A 1 267 ? 21.912 56.055 10.385 1.00 9.51 ? 267 TYR A N 1 ATOM 2079 C CA . TYR A 1 267 ? 21.955 57.342 9.743 1.00 9.59 ? 267 TYR A CA 1 ATOM 2080 C C . TYR A 1 267 ? 23.302 58.042 9.913 1.00 9.62 ? 267 TYR A C 1 ATOM 2081 O O . TYR A 1 267 ? 23.663 58.832 9.051 1.00 9.01 ? 267 TYR A O 1 ATOM 2082 C CB . TYR A 1 267 ? 20.815 58.197 10.302 1.00 10.65 ? 267 TYR A CB 1 ATOM 2083 C CG . TYR A 1 267 ? 20.930 59.693 10.132 1.00 11.03 ? 267 TYR A CG 1 ATOM 2084 C CD1 . TYR A 1 267 ? 20.611 60.327 8.927 1.00 13.12 ? 267 TYR A CD1 1 ATOM 2085 C CD2 . TYR A 1 267 ? 21.307 60.486 11.213 1.00 12.30 ? 267 TYR A CD2 1 ATOM 2086 C CE1 . TYR A 1 267 ? 20.696 61.728 8.814 1.00 12.89 ? 267 TYR A CE1 1 ATOM 2087 C CE2 . TYR A 1 267 ? 21.402 61.841 11.108 1.00 13.74 ? 267 TYR A CE2 1 ATOM 2088 C CZ . TYR A 1 267 ? 21.097 62.453 9.924 1.00 13.39 ? 267 TYR A CZ 1 ATOM 2089 O OH . TYR A 1 267 ? 21.200 63.846 9.872 1.00 17.92 ? 267 TYR A OH 1 ATOM 2090 N N . SER A 1 268 ? 24.020 57.776 10.991 1.00 9.20 ? 268 SER A N 1 ATOM 2091 C CA . SER A 1 268 ? 25.265 58.494 11.269 1.00 9.76 ? 268 SER A CA 1 ATOM 2092 C C . SER A 1 268 ? 26.283 57.568 11.913 1.00 9.81 ? 268 SER A C 1 ATOM 2093 O O . SER A 1 268 ? 25.960 56.453 12.382 1.00 10.09 ? 268 SER A O 1 ATOM 2094 C CB . SER A 1 268 ? 24.963 59.720 12.152 1.00 9.99 ? 268 SER A CB 1 ATOM 2095 O OG . SER A 1 268 ? 26.126 60.302 12.712 1.00 13.41 ? 268 SER A OG 1 ATOM 2096 N N . TYR A 1 269 ? 27.540 58.039 11.946 1.00 9.68 ? 269 TYR A N 1 ATOM 2097 C CA . TYR A 1 269 ? 28.565 57.330 12.693 1.00 9.20 ? 269 TYR A CA 1 ATOM 2098 C C . TYR A 1 269 ? 28.704 57.814 14.147 1.00 9.18 ? 269 TYR A C 1 ATOM 2099 O O . TYR A 1 269 ? 29.578 57.328 14.872 1.00 9.73 ? 269 TYR A O 1 ATOM 2100 C CB . TYR A 1 269 ? 29.924 57.458 11.961 1.00 8.13 ? 269 TYR A CB 1 ATOM 2101 C CG . TYR A 1 269 ? 30.399 58.876 11.713 1.00 9.25 ? 269 TYR A CG 1 ATOM 2102 C CD1 . TYR A 1 269 ? 30.875 59.689 12.758 1.00 10.08 ? 269 TYR A CD1 1 ATOM 2103 C CD2 . TYR A 1 269 ? 30.363 59.409 10.417 1.00 10.15 ? 269 TYR A CD2 1 ATOM 2104 C CE1 . TYR A 1 269 ? 31.337 61.012 12.504 1.00 11.11 ? 269 TYR A CE1 1 ATOM 2105 C CE2 . TYR A 1 269 ? 30.848 60.706 10.164 1.00 9.13 ? 269 TYR A CE2 1 ATOM 2106 C CZ . TYR A 1 269 ? 31.330 61.499 11.198 1.00 9.71 ? 269 TYR A CZ 1 ATOM 2107 O OH . TYR A 1 269 ? 31.784 62.782 10.927 1.00 10.53 ? 269 TYR A OH 1 ATOM 2108 N N . ASP A 1 270 ? 27.857 58.749 14.559 1.00 9.89 ? 270 ASP A N 1 ATOM 2109 C CA . ASP A 1 270 ? 27.887 59.197 15.956 1.00 10.36 ? 270 ASP A CA 1 ATOM 2110 C C . ASP A 1 270 ? 27.298 58.171 16.933 1.00 9.24 ? 270 ASP A C 1 ATOM 2111 O O . ASP A 1 270 ? 26.749 57.156 16.503 1.00 9.97 ? 270 ASP A O 1 ATOM 2112 C CB . ASP A 1 270 ? 27.256 60.575 16.089 1.00 11.42 ? 270 ASP A CB 1 ATOM 2113 C CG . ASP A 1 270 ? 25.765 60.594 15.855 1.00 12.63 ? 270 ASP A CG 1 ATOM 2114 O OD1 . ASP A 1 270 ? 25.103 59.528 15.725 1.00 13.38 ? 270 ASP A OD1 1 ATOM 2115 O OD2 . ASP A 1 270 ? 25.157 61.701 15.859 1.00 14.53 ? 270 ASP A OD2 1 ATOM 2116 N N . ILE A 1 271 ? 27.502 58.395 18.228 1.00 9.55 ? 271 ILE A N 1 ATOM 2117 C CA . ILE A 1 271 ? 27.101 57.377 19.223 1.00 9.95 ? 271 ILE A CA 1 ATOM 2118 C C . ILE A 1 271 ? 25.579 57.103 19.194 1.00 9.32 ? 271 ILE A C 1 ATOM 2119 O O . ILE A 1 271 ? 25.190 55.931 19.181 1.00 9.44 ? 271 ILE A O 1 ATOM 2120 C CB . ILE A 1 271 ? 27.655 57.689 20.608 1.00 10.37 ? 271 ILE A CB 1 ATOM 2121 C CG1 . ILE A 1 271 ? 29.194 57.558 20.564 1.00 10.44 ? 271 ILE A CG1 1 ATOM 2122 C CG2 . ILE A 1 271 ? 27.056 56.713 21.656 1.00 10.42 ? 271 ILE A CG2 1 ATOM 2123 C CD1 . ILE A 1 271 ? 29.884 58.214 21.737 1.00 10.63 ? 271 ILE A CD1 1 ATOM 2124 N N . PRO A 1 272 ? 24.731 58.128 19.092 1.00 9.41 ? 272 PRO A N 1 ATOM 2125 C CA . PRO A 1 272 ? 23.286 57.848 18.985 1.00 10.19 ? 272 PRO A CA 1 ATOM 2126 C C . PRO A 1 272 ? 22.920 56.923 17.845 1.00 11.20 ? 272 PRO A C 1 ATOM 2127 O O . PRO A 1 272 ? 21.878 56.248 17.945 1.00 11.57 ? 272 PRO A O 1 ATOM 2128 C CB . PRO A 1 272 ? 22.667 59.227 18.786 1.00 11.02 ? 272 PRO A CB 1 ATOM 2129 C CG . PRO A 1 272 ? 23.598 60.149 19.536 1.00 11.06 ? 272 PRO A CG 1 ATOM 2130 C CD . PRO A 1 272 ? 24.983 59.580 19.207 1.00 11.03 ? 272 PRO A CD 1 ATOM 2131 N N . HIS A 1 273 ? 23.718 56.869 16.779 1.00 10.02 ? 273 HIS A N 1 ATOM 2132 C CA . HIS A 1 273 ? 23.368 56.021 15.629 1.00 9.60 ? 273 HIS A CA 1 ATOM 2133 C C . HIS A 1 273 ? 24.286 54.832 15.416 1.00 9.64 ? 273 HIS A C 1 ATOM 2134 O O . HIS A 1 273 ? 24.318 54.260 14.313 1.00 10.36 ? 273 HIS A O 1 ATOM 2135 C CB . HIS A 1 273 ? 23.221 56.859 14.337 1.00 9.60 ? 273 HIS A CB 1 ATOM 2136 C CG . HIS A 1 273 ? 22.158 57.906 14.443 1.00 10.37 ? 273 HIS A CG 1 ATOM 2137 N ND1 . HIS A 1 273 ? 22.400 59.164 14.956 1.00 11.30 ? 273 HIS A ND1 1 ATOM 2138 C CD2 . HIS A 1 273 ? 20.828 57.862 14.160 1.00 10.56 ? 273 HIS A CD2 1 ATOM 2139 C CE1 . HIS A 1 273 ? 21.265 59.856 14.978 1.00 12.03 ? 273 HIS A CE1 1 ATOM 2140 N NE2 . HIS A 1 273 ? 20.303 59.088 14.493 1.00 11.11 ? 273 HIS A NE2 1 ATOM 2141 N N . THR A 1 274 ? 25.001 54.434 16.470 1.00 9.68 ? 274 THR A N 1 ATOM 2142 C CA . THR A 1 274 ? 25.874 53.273 16.347 1.00 10.24 ? 274 THR A CA 1 ATOM 2143 C C . THR A 1 274 ? 25.639 52.206 17.422 1.00 10.34 ? 274 THR A C 1 ATOM 2144 O O . THR A 1 274 ? 26.197 51.121 17.300 1.00 11.94 ? 274 THR A O 1 ATOM 2145 C CB . THR A 1 274 ? 27.377 53.682 16.310 1.00 10.33 ? 274 THR A CB 1 ATOM 2146 O OG1 . THR A 1 274 ? 27.649 54.623 17.362 1.00 10.61 ? 274 THR A OG1 1 ATOM 2147 C CG2 . THR A 1 274 ? 27.717 54.360 14.971 1.00 11.97 ? 274 THR A CG2 1 ATOM 2148 N N . CYS A 1 275 ? 24.847 52.473 18.466 1.00 11.51 ? 275 CYS A N 1 ATOM 2149 C CA . CYS A 1 275 ? 24.651 51.384 19.450 1.00 11.96 ? 275 CYS A CA 1 ATOM 2150 C C . CYS A 1 275 ? 23.519 50.403 19.052 1.00 11.72 ? 275 CYS A C 1 ATOM 2151 O O . CYS A 1 275 ? 23.457 49.253 19.528 1.00 13.12 ? 275 CYS A O 1 ATOM 2152 C CB . CYS A 1 275 ? 24.393 51.976 20.847 1.00 12.64 ? 275 CYS A CB 1 ATOM 2153 S SG . CYS A 1 275 ? 22.674 52.036 21.416 1.00 15.30 ? 275 CYS A SG 1 ATOM 2154 N N . GLY A 1 276 ? 22.633 50.872 18.204 1.00 11.29 ? 276 GLY A N 1 ATOM 2155 C CA . GLY A 1 276 ? 21.375 50.182 17.921 1.00 12.22 ? 276 GLY A CA 1 ATOM 2156 C C . GLY A 1 276 ? 20.427 51.107 17.209 1.00 11.50 ? 276 GLY A C 1 ATOM 2157 O O . GLY A 1 276 ? 20.802 52.239 16.896 1.00 11.66 ? 276 GLY A O 1 ATOM 2158 N N . PRO A 1 277 ? 19.195 50.647 16.917 1.00 11.59 ? 277 PRO A N 1 ATOM 2159 C CA . PRO A 1 277 ? 18.256 51.392 16.079 1.00 11.71 ? 277 PRO A CA 1 ATOM 2160 C C . PRO A 1 277 ? 17.564 52.593 16.698 1.00 11.35 ? 277 PRO A C 1 ATOM 2161 O O . PRO A 1 277 ? 16.973 53.341 15.934 1.00 11.60 ? 277 PRO A O 1 ATOM 2162 C CB . PRO A 1 277 ? 17.159 50.354 15.758 1.00 12.35 ? 277 PRO A CB 1 ATOM 2163 C CG . PRO A 1 277 ? 17.234 49.338 16.902 1.00 11.05 ? 277 PRO A CG 1 ATOM 2164 C CD . PRO A 1 277 ? 18.684 49.307 17.289 1.00 12.65 ? 277 PRO A CD 1 ATOM 2165 N N . ASP A 1 278 ? 17.620 52.748 18.009 1.00 11.89 ? 278 ASP A N 1 ATOM 2166 C CA . ASP A 1 278 ? 16.880 53.835 18.662 1.00 12.21 ? 278 ASP A CA 1 ATOM 2167 C C . ASP A 1 278 ? 17.826 54.887 19.235 1.00 11.67 ? 278 ASP A C 1 ATOM 2168 O O . ASP A 1 278 ? 18.423 54.670 20.283 1.00 12.32 ? 278 ASP A O 1 ATOM 2169 C CB . ASP A 1 278 ? 16.020 53.277 19.799 1.00 12.70 ? 278 ASP A CB 1 ATOM 2170 C CG . ASP A 1 278 ? 15.128 54.331 20.409 1.00 15.88 ? 278 ASP A CG 1 ATOM 2171 O OD1 . ASP A 1 278 ? 15.224 55.544 20.078 1.00 17.78 ? 278 ASP A OD1 1 ATOM 2172 O OD2 . ASP A 1 278 ? 14.253 54.015 21.252 1.00 17.60 ? 278 ASP A OD2 1 ATOM 2173 N N . PRO A 1 279 ? 17.969 56.012 18.535 1.00 12.78 ? 279 PRO A N 1 ATOM 2174 C CA . PRO A 1 279 ? 18.948 57.010 19.005 1.00 13.63 ? 279 PRO A CA 1 ATOM 2175 C C . PRO A 1 279 ? 18.594 57.642 20.346 1.00 13.09 ? 279 PRO A C 1 ATOM 2176 O O . PRO A 1 279 ? 19.497 58.083 21.072 1.00 13.21 ? 279 PRO A O 1 ATOM 2177 C CB . PRO A 1 279 ? 18.948 58.065 17.893 1.00 13.96 ? 279 PRO A CB 1 ATOM 2178 C CG . PRO A 1 279 ? 17.621 57.933 17.239 1.00 14.29 ? 279 PRO A CG 1 ATOM 2179 C CD . PRO A 1 279 ? 17.246 56.453 17.330 1.00 13.14 ? 279 PRO A CD 1 ATOM 2180 N N . LYS A 1 280 ? 17.300 57.632 20.709 1.00 13.65 ? 280 LYS A N 1 ATOM 2181 C CA . LYS A 1 280 ? 16.906 58.148 22.023 1.00 14.71 ? 280 LYS A CA 1 ATOM 2182 C C . LYS A 1 280 ? 17.525 57.325 23.130 1.00 13.65 ? 280 LYS A C 1 ATOM 2183 O O . LYS A 1 280 ? 17.911 57.854 24.170 1.00 15.25 ? 280 LYS A O 1 ATOM 2184 C CB . LYS A 1 280 ? 15.386 58.178 22.148 1.00 15.01 ? 280 LYS A CB 1 ATOM 2185 C CG . LYS A 1 280 ? 14.883 58.637 23.500 1.00 18.31 ? 280 LYS A CG 1 ATOM 2186 C CD . LYS A 1 280 ? 13.357 58.583 23.525 1.00 22.80 ? 280 LYS A CD 1 ATOM 2187 C CE . LYS A 1 280 ? 12.846 58.738 24.950 1.00 28.77 ? 280 LYS A CE 1 ATOM 2188 N NZ . LYS A 1 280 ? 13.367 57.650 25.842 1.00 32.62 ? 280 LYS A NZ 1 ATOM 2189 N N . VAL A 1 281 ? 17.687 56.023 22.881 1.00 13.91 ? 281 VAL A N 1 ATOM 2190 C CA . VAL A 1 281 ? 18.359 55.137 23.822 1.00 13.97 ? 281 VAL A CA 1 ATOM 2191 C C . VAL A 1 281 ? 19.895 55.218 23.701 1.00 13.23 ? 281 VAL A C 1 ATOM 2192 O O . VAL A 1 281 ? 20.591 55.372 24.707 1.00 12.59 ? 281 VAL A O 1 ATOM 2193 C CB . VAL A 1 281 ? 17.886 53.655 23.664 1.00 13.98 ? 281 VAL A CB 1 ATOM 2194 C CG1 . VAL A 1 281 ? 18.677 52.741 24.589 1.00 14.25 ? 281 VAL A CG1 1 ATOM 2195 C CG2 . VAL A 1 281 ? 16.339 53.555 23.906 1.00 13.74 ? 281 VAL A CG2 1 ATOM 2196 N N . CYS A 1 282 ? 20.417 55.101 22.470 1.00 12.75 ? 282 CYS A N 1 ATOM 2197 C CA . CYS A 1 282 ? 21.872 55.114 22.272 1.00 13.09 ? 282 CYS A CA 1 ATOM 2198 C C . CYS A 1 282 ? 22.510 56.408 22.787 1.00 11.35 ? 282 CYS A C 1 ATOM 2199 O O . CYS A 1 282 ? 23.609 56.369 23.322 1.00 11.63 ? 282 CYS A O 1 ATOM 2200 C CB . CYS A 1 282 ? 22.205 54.954 20.791 1.00 12.77 ? 282 CYS A CB 1 ATOM 2201 S SG . CYS A 1 282 ? 21.777 53.347 20.157 1.00 14.69 ? 282 CYS A SG 1 ATOM 2202 N N . CYS A 1 283 ? 21.810 57.529 22.642 1.00 11.96 ? 283 CYS A N 1 ATOM 2203 C CA . CYS A 1 283 ? 22.341 58.792 23.141 1.00 11.99 ? 283 CYS A CA 1 ATOM 2204 C C . CYS A 1 283 ? 22.638 58.771 24.636 1.00 12.08 ? 283 CYS A C 1 ATOM 2205 O O . CYS A 1 283 ? 23.527 59.462 25.102 1.00 11.94 ? 283 CYS A O 1 ATOM 2206 C CB . CYS A 1 283 ? 21.397 59.932 22.800 1.00 12.94 ? 283 CYS A CB 1 ATOM 2207 S SG . CYS A 1 283 ? 22.170 61.557 22.880 1.00 15.33 ? 283 CYS A SG 1 ATOM 2208 N N . GLN A 1 284 ? 21.899 57.935 25.391 1.00 11.82 ? 284 GLN A N 1 ATOM 2209 C CA . GLN A 1 284 ? 22.131 57.808 26.827 1.00 12.40 ? 284 GLN A CA 1 ATOM 2210 C C . GLN A 1 284 ? 23.385 57.068 27.164 1.00 12.41 ? 284 GLN A C 1 ATOM 2211 O O . GLN A 1 284 ? 23.766 56.978 28.324 1.00 13.90 ? 284 GLN A O 1 ATOM 2212 C CB . GLN A 1 284 ? 20.945 57.118 27.509 1.00 12.29 ? 284 GLN A CB 1 ATOM 2213 C CG . GLN A 1 284 ? 19.654 57.871 27.331 1.00 14.83 ? 284 GLN A CG 1 ATOM 2214 C CD . GLN A 1 284 ? 18.472 57.071 27.853 1.00 15.60 ? 284 GLN A CD 1 ATOM 2215 O OE1 . GLN A 1 284 ? 18.492 56.614 29.006 1.00 17.19 ? 284 GLN A OE1 1 ATOM 2216 N NE2 . GLN A 1 284 ? 17.488 56.863 27.004 1.00 17.05 ? 284 GLN A NE2 1 ATOM 2217 N N . PHE A 1 285 ? 24.056 56.541 26.133 1.00 11.67 ? 285 PHE A N 1 ATOM 2218 C CA . PHE A 1 285 ? 25.313 55.835 26.333 1.00 11.82 ? 285 PHE A CA 1 ATOM 2219 C C . PHE A 1 285 ? 26.500 56.583 25.691 1.00 11.44 ? 285 PHE A C 1 ATOM 2220 O O . PHE A 1 285 ? 27.586 56.012 25.489 1.00 11.68 ? 285 PHE A O 1 ATOM 2221 C CB . PHE A 1 285 ? 25.188 54.371 25.904 1.00 12.86 ? 285 PHE A CB 1 ATOM 2222 C CG . PHE A 1 285 ? 24.188 53.633 26.750 1.00 11.86 ? 285 PHE A CG 1 ATOM 2223 C CD1 . PHE A 1 285 ? 24.573 53.042 27.942 1.00 13.38 ? 285 PHE A CD1 1 ATOM 2224 C CD2 . PHE A 1 285 ? 22.858 53.594 26.364 1.00 14.13 ? 285 PHE A CD2 1 ATOM 2225 C CE1 . PHE A 1 285 ? 23.608 52.408 28.776 1.00 12.02 ? 285 PHE A CE1 1 ATOM 2226 C CE2 . PHE A 1 285 ? 21.902 52.961 27.192 1.00 14.29 ? 285 PHE A CE2 1 ATOM 2227 C CZ . PHE A 1 285 ? 22.296 52.361 28.367 1.00 14.46 ? 285 PHE A CZ 1 ATOM 2228 N N . ASP A 1 286 ? 26.256 57.868 25.415 1.00 11.10 ? 286 ASP A N 1 ATOM 2229 C CA . ASP A 1 286 ? 27.336 58.806 25.067 1.00 10.74 ? 286 ASP A CA 1 ATOM 2230 C C . ASP A 1 286 ? 27.591 59.637 26.319 1.00 10.45 ? 286 ASP A C 1 ATOM 2231 O O . ASP A 1 286 ? 26.908 60.640 26.537 1.00 11.92 ? 286 ASP A O 1 ATOM 2232 C CB . ASP A 1 286 ? 26.914 59.686 23.907 1.00 11.57 ? 286 ASP A CB 1 ATOM 2233 C CG . ASP A 1 286 ? 28.046 60.563 23.398 1.00 9.10 ? 286 ASP A CG 1 ATOM 2234 O OD1 . ASP A 1 286 ? 29.089 60.639 24.083 1.00 10.18 ? 286 ASP A OD1 1 ATOM 2235 O OD2 . ASP A 1 286 ? 27.876 61.229 22.350 1.00 11.60 ? 286 ASP A OD2 1 ATOM 2236 N N . PHE A 1 287 ? 28.582 59.236 27.103 1.00 10.38 ? 287 PHE A N 1 ATOM 2237 C CA . PHE A 1 287 ? 28.747 59.838 28.425 1.00 11.02 ? 287 PHE A CA 1 ATOM 2238 C C . PHE A 1 287 ? 29.343 61.232 28.376 1.00 12.57 ? 287 PHE A C 1 ATOM 2239 O O . PHE A 1 287 ? 29.423 61.903 29.427 1.00 13.18 ? 287 PHE A O 1 ATOM 2240 C CB . PHE A 1 287 ? 29.484 58.867 29.368 1.00 11.17 ? 287 PHE A CB 1 ATOM 2241 C CG . PHE A 1 287 ? 28.677 57.609 29.634 1.00 12.12 ? 287 PHE A CG 1 ATOM 2242 C CD1 . PHE A 1 287 ? 27.675 57.587 30.644 1.00 13.46 ? 287 PHE A CD1 1 ATOM 2243 C CD2 . PHE A 1 287 ? 28.850 56.475 28.854 1.00 12.39 ? 287 PHE A CD2 1 ATOM 2244 C CE1 . PHE A 1 287 ? 26.892 56.433 30.851 1.00 13.20 ? 287 PHE A CE1 1 ATOM 2245 C CE2 . PHE A 1 287 ? 28.073 55.311 29.056 1.00 13.57 ? 287 PHE A CE2 1 ATOM 2246 C CZ . PHE A 1 287 ? 27.083 55.297 30.058 1.00 12.31 ? 287 PHE A CZ 1 ATOM 2247 N N . LYS A 1 288 ? 29.655 61.733 27.173 1.00 12.70 ? 288 LYS A N 1 ATOM 2248 C CA . LYS A 1 288 ? 30.049 63.129 27.046 1.00 12.68 ? 288 LYS A CA 1 ATOM 2249 C C . LYS A 1 288 ? 28.844 64.073 27.027 1.00 13.73 ? 288 LYS A C 1 ATOM 2250 O O . LYS A 1 288 ? 29.023 65.312 27.039 1.00 13.70 ? 288 LYS A O 1 ATOM 2251 C CB . LYS A 1 288 ? 30.920 63.316 25.782 1.00 13.33 ? 288 LYS A CB 1 ATOM 2252 C CG . LYS A 1 288 ? 31.756 64.598 25.849 1.00 12.06 ? 288 LYS A CG 1 ATOM 2253 C CD . LYS A 1 288 ? 32.581 64.788 24.564 1.00 11.49 ? 288 LYS A CD 1 ATOM 2254 C CE . LYS A 1 288 ? 33.394 66.054 24.727 1.00 12.99 ? 288 LYS A CE 1 ATOM 2255 N NZ . LYS A 1 288 ? 34.450 66.190 23.635 1.00 14.14 ? 288 LYS A NZ 1 ATOM 2256 N N . ARG A 1 289 ? 27.622 63.543 27.030 1.00 14.21 ? 289 ARG A N 1 ATOM 2257 C CA . ARG A 1 289 ? 26.444 64.393 26.875 1.00 15.45 ? 289 ARG A CA 1 ATOM 2258 C C . ARG A 1 289 ? 25.656 64.735 28.174 1.00 17.41 ? 289 ARG A C 1 ATOM 2259 O O . ARG A 1 289 ? 24.454 64.982 28.097 1.00 17.78 ? 289 ARG A O 1 ATOM 2260 C CB . ARG A 1 289 ? 25.492 63.774 25.849 1.00 14.31 ? 289 ARG A CB 1 ATOM 2261 C CG . ARG A 1 289 ? 26.093 63.663 24.462 1.00 14.55 ? 289 ARG A CG 1 ATOM 2262 C CD . ARG A 1 289 ? 25.105 63.224 23.469 1.00 14.20 ? 289 ARG A CD 1 ATOM 2263 N NE . ARG A 1 289 ? 25.633 62.911 22.146 1.00 13.19 ? 289 ARG A NE 1 ATOM 2264 C CZ . ARG A 1 289 ? 25.183 63.438 21.014 1.00 13.48 ? 289 ARG A CZ 1 ATOM 2265 N NH1 . ARG A 1 289 ? 24.226 64.359 21.013 1.00 15.12 ? 289 ARG A NH1 1 ATOM 2266 N NH2 . ARG A 1 289 ? 25.687 63.006 19.868 1.00 13.64 ? 289 ARG A NH2 1 ATOM 2267 N N . MET A 1 290 ? 26.308 64.742 29.336 1.00 20.00 ? 290 MET A N 1 ATOM 2268 C CA . MET A 1 290 ? 25.559 65.003 30.590 1.00 22.16 ? 290 MET A CA 1 ATOM 2269 C C . MET A 1 290 ? 25.483 66.494 31.020 1.00 23.18 ? 290 MET A C 1 ATOM 2270 O O . MET A 1 290 ? 24.718 66.840 31.962 1.00 24.85 ? 290 MET A O 1 ATOM 2271 C CB . MET A 1 290 ? 25.989 64.058 31.738 1.00 21.35 ? 290 MET A CB 1 ATOM 2272 C CG . MET A 1 290 ? 25.898 62.604 31.386 1.00 22.64 ? 290 MET A CG 1 ATOM 2273 S SD . MET A 1 290 ? 26.347 61.475 32.754 1.00 24.39 ? 290 MET A SD 1 ATOM 2274 C CE . MET A 1 290 ? 28.161 61.439 32.619 1.00 26.21 ? 290 MET A CE 1 ATOM 2275 N N . GLY A 1 291 ? 26.245 67.368 30.340 1.00 22.88 ? 291 GLY A N 1 ATOM 2276 C CA . GLY A 1 291 ? 26.121 68.811 30.533 1.00 21.74 ? 291 GLY A CA 1 ATOM 2277 C C . GLY A 1 291 ? 27.400 69.664 30.629 1.00 21.46 ? 291 GLY A C 1 ATOM 2278 O O . GLY A 1 291 ? 27.478 70.757 30.034 1.00 22.39 ? 291 GLY A O 1 ATOM 2279 N N . SER A 1 292 ? 28.403 69.186 31.368 1.00 19.90 ? 292 SER A N 1 ATOM 2280 C CA . SER A 1 292 ? 29.624 69.967 31.615 1.00 17.88 ? 292 SER A CA 1 ATOM 2281 C C . SER A 1 292 ? 30.495 70.148 30.357 1.00 16.81 ? 292 SER A C 1 ATOM 2282 O O . SER A 1 292 ? 31.393 71.016 30.339 1.00 15.43 ? 292 SER A O 1 ATOM 2283 C CB . SER A 1 292 ? 30.443 69.289 32.704 1.00 19.61 ? 292 SER A CB 1 ATOM 2284 O OG . SER A 1 292 ? 30.889 68.019 32.240 1.00 20.04 ? 292 SER A OG 1 ATOM 2285 N N . PHE A 1 293 ? 30.242 69.311 29.340 1.00 14.79 ? 293 PHE A N 1 ATOM 2286 C CA . PHE A 1 293 ? 30.948 69.384 28.060 1.00 14.65 ? 293 PHE A CA 1 ATOM 2287 C C . PHE A 1 293 ? 30.175 70.219 27.050 1.00 14.25 ? 293 PHE A C 1 ATOM 2288 O O . PHE A 1 293 ? 30.610 70.333 25.906 1.00 14.86 ? 293 PHE A O 1 ATOM 2289 C CB . PHE A 1 293 ? 31.174 67.973 27.491 1.00 15.06 ? 293 PHE A CB 1 ATOM 2290 C CG . PHE A 1 293 ? 32.076 67.124 28.327 1.00 14.81 ? 293 PHE A CG 1 ATOM 2291 C CD1 . PHE A 1 293 ? 33.453 67.235 28.218 1.00 14.40 ? 293 PHE A CD1 1 ATOM 2292 C CD2 . PHE A 1 293 ? 31.539 66.210 29.206 1.00 15.91 ? 293 PHE A CD2 1 ATOM 2293 C CE1 . PHE A 1 293 ? 34.306 66.423 28.989 1.00 16.44 ? 293 PHE A CE1 1 ATOM 2294 C CE2 . PHE A 1 293 ? 32.378 65.398 29.986 1.00 16.22 ? 293 PHE A CE2 1 ATOM 2295 C CZ . PHE A 1 293 ? 33.745 65.519 29.870 1.00 16.55 ? 293 PHE A CZ 1 ATOM 2296 N N . GLY A 1 294 ? 29.037 70.784 27.450 1.00 14.28 ? 294 GLY A N 1 ATOM 2297 C CA . GLY A 1 294 ? 28.279 71.602 26.523 1.00 15.61 ? 294 GLY A CA 1 ATOM 2298 C C . GLY A 1 294 ? 27.582 70.799 25.437 1.00 15.89 ? 294 GLY A C 1 ATOM 2299 O O . GLY A 1 294 ? 27.275 71.302 24.354 1.00 16.25 ? 294 GLY A O 1 ATOM 2300 N N . LEU A 1 295 ? 27.347 69.527 25.732 1.00 14.99 ? 295 LEU A N 1 ATOM 2301 C CA . LEU A 1 295 ? 26.608 68.658 24.835 1.00 15.19 ? 295 LEU A CA 1 ATOM 2302 C C . LEU A 1 295 ? 25.378 68.122 25.550 1.00 16.28 ? 295 LEU A C 1 ATOM 2303 O O . LEU A 1 295 ? 25.332 68.067 26.773 1.00 17.03 ? 295 LEU A O 1 ATOM 2304 C CB . LEU A 1 295 ? 27.500 67.523 24.321 1.00 15.83 ? 295 LEU A CB 1 ATOM 2305 C CG . LEU A 1 295 ? 28.794 67.916 23.607 1.00 15.29 ? 295 LEU A CG 1 ATOM 2306 C CD1 . LEU A 1 295 ? 29.600 66.633 23.351 1.00 17.95 ? 295 LEU A CD1 1 ATOM 2307 C CD2 . LEU A 1 295 ? 28.516 68.699 22.301 1.00 18.58 ? 295 LEU A CD2 1 ATOM 2308 N N . SER A 1 296 ? 24.385 67.745 24.755 1.00 16.52 ? 296 SER A N 1 ATOM 2309 C CA . SER A 1 296 ? 23.133 67.189 25.288 1.00 17.83 ? 296 SER A CA 1 ATOM 2310 C C . SER A 1 296 ? 22.557 66.238 24.268 1.00 18.10 ? 296 SER A C 1 ATOM 2311 O O . SER A 1 296 ? 23.085 66.110 23.165 1.00 16.95 ? 296 SER A O 1 ATOM 2312 C CB . SER A 1 296 ? 22.135 68.311 25.656 1.00 18.01 ? 296 SER A CB 1 ATOM 2313 O OG . SER A 1 296 ? 21.872 69.171 24.561 1.00 20.65 ? 296 SER A OG 1 ATOM 2314 N N . CYS A 1 297 ? 21.486 65.540 24.661 1.00 17.07 ? 297 CYS A N 1 ATOM 2315 C CA . CYS A 1 297 ? 20.774 64.594 23.801 1.00 18.01 ? 297 CYS A CA 1 ATOM 2316 C C . CYS A 1 297 ? 19.516 65.251 23.239 1.00 18.24 ? 297 CYS A C 1 ATOM 2317 O O . CYS A 1 297 ? 18.641 65.652 24.029 1.00 19.34 ? 297 CYS A O 1 ATOM 2318 C CB . CYS A 1 297 ? 20.388 63.361 24.637 1.00 17.81 ? 297 CYS A CB 1 ATOM 2319 S SG . CYS A 1 297 ? 21.776 62.200 24.836 1.00 19.58 ? 297 CYS A SG 1 ATOM 2320 N N . PRO A 1 298 ? 19.416 65.418 21.919 1.00 18.87 ? 298 PRO A N 1 ATOM 2321 C CA . PRO A 1 298 ? 18.230 66.058 21.318 1.00 19.32 ? 298 PRO A CA 1 ATOM 2322 C C . PRO A 1 298 ? 16.936 65.262 21.515 1.00 19.00 ? 298 PRO A C 1 ATOM 2323 O O . PRO A 1 298 ? 15.856 65.847 21.349 1.00 19.89 ? 298 PRO A O 1 ATOM 2324 C CB . PRO A 1 298 ? 18.591 66.212 19.830 1.00 20.95 ? 298 PRO A CB 1 ATOM 2325 C CG . PRO A 1 298 ? 19.814 65.398 19.594 1.00 20.11 ? 298 PRO A CG 1 ATOM 2326 C CD . PRO A 1 298 ? 20.460 65.116 20.912 1.00 18.51 ? 298 PRO A CD 1 ATOM 2327 N N . TRP A 1 299 ? 17.037 63.993 21.898 1.00 18.62 ? 299 TRP A N 1 ATOM 2328 C CA . TRP A 1 299 ? 15.847 63.167 22.183 1.00 18.34 ? 299 TRP A CA 1 ATOM 2329 C C . TRP A 1 299 ? 15.388 63.331 23.625 1.00 19.66 ? 299 TRP A C 1 ATOM 2330 O O . TRP A 1 299 ? 14.450 62.652 24.073 1.00 19.48 ? 299 TRP A O 1 ATOM 2331 C CB . TRP A 1 299 ? 16.121 61.685 21.850 1.00 17.28 ? 299 TRP A CB 1 ATOM 2332 C CG . TRP A 1 299 ? 16.490 61.516 20.412 1.00 17.05 ? 299 TRP A CG 1 ATOM 2333 C CD1 . TRP A 1 299 ? 15.643 61.345 19.374 1.00 15.98 ? 299 TRP A CD1 1 ATOM 2334 C CD2 . TRP A 1 299 ? 17.809 61.609 19.848 1.00 15.87 ? 299 TRP A CD2 1 ATOM 2335 N NE1 . TRP A 1 299 ? 16.342 61.287 18.187 1.00 17.45 ? 299 TRP A NE1 1 ATOM 2336 C CE2 . TRP A 1 299 ? 17.678 61.427 18.461 1.00 17.07 ? 299 TRP A CE2 1 ATOM 2337 C CE3 . TRP A 1 299 ? 19.084 61.781 20.390 1.00 16.98 ? 299 TRP A CE3 1 ATOM 2338 C CZ2 . TRP A 1 299 ? 18.773 61.460 17.595 1.00 16.57 ? 299 TRP A CZ2 1 ATOM 2339 C CZ3 . TRP A 1 299 ? 20.173 61.787 19.534 1.00 17.16 ? 299 TRP A CZ3 1 ATOM 2340 C CH2 . TRP A 1 299 ? 20.004 61.637 18.153 1.00 16.15 ? 299 TRP A CH2 1 ATOM 2341 N N . LYS A 1 300 ? 16.075 64.202 24.356 1.00 19.97 ? 300 LYS A N 1 ATOM 2342 C CA . LYS A 1 300 ? 15.612 64.734 25.652 1.00 20.69 ? 300 LYS A CA 1 ATOM 2343 C C . LYS A 1 300 ? 15.772 63.812 26.861 1.00 21.13 ? 300 LYS A C 1 ATOM 2344 O O . LYS A 1 300 ? 15.285 64.111 27.962 1.00 21.70 ? 300 LYS A O 1 ATOM 2345 C CB . LYS A 1 300 ? 14.168 65.219 25.551 1.00 21.37 ? 300 LYS A CB 1 ATOM 2346 C CG . LYS A 1 300 ? 13.994 66.392 24.636 1.00 21.97 ? 300 LYS A CG 1 ATOM 2347 C CD . LYS A 1 300 ? 12.506 66.721 24.517 1.00 28.20 ? 300 LYS A CD 1 ATOM 2348 C CE . LYS A 1 300 ? 12.224 67.686 23.380 1.00 31.83 ? 300 LYS A CE 1 ATOM 2349 N NZ . LYS A 1 300 ? 10.781 67.577 22.979 1.00 36.74 ? 300 LYS A NZ 1 ATOM 2350 N N . VAL A 1 301 ? 16.446 62.684 26.683 1.00 20.36 ? 301 VAL A N 1 ATOM 2351 C CA . VAL A 1 301 ? 16.773 61.823 27.802 1.00 19.75 ? 301 VAL A CA 1 ATOM 2352 C C . VAL A 1 301 ? 18.296 61.807 27.904 1.00 19.12 ? 301 VAL A C 1 ATOM 2353 O O . VAL A 1 301 ? 18.968 61.317 26.982 1.00 20.46 ? 301 VAL A O 1 ATOM 2354 C CB . VAL A 1 301 ? 16.231 60.382 27.626 1.00 19.56 ? 301 VAL A CB 1 ATOM 2355 C CG1 . VAL A 1 301 ? 16.526 59.563 28.878 1.00 20.13 ? 301 VAL A CG1 1 ATOM 2356 C CG2 . VAL A 1 301 ? 14.726 60.400 27.351 1.00 21.51 ? 301 VAL A CG2 1 ATOM 2357 N N . PRO A 1 302 ? 18.849 62.342 28.984 1.00 18.26 ? 302 PRO A N 1 ATOM 2358 C CA . PRO A 1 302 ? 20.303 62.457 29.109 1.00 18.23 ? 302 PRO A CA 1 ATOM 2359 C C . PRO A 1 302 ? 20.932 61.125 29.497 1.00 18.00 ? 302 PRO A C 1 ATOM 2360 O O . PRO A 1 302 ? 20.265 60.226 30.010 1.00 18.23 ? 302 PRO A O 1 ATOM 2361 C CB . PRO A 1 302 ? 20.484 63.503 30.221 1.00 19.15 ? 302 PRO A CB 1 ATOM 2362 C CG . PRO A 1 302 ? 19.164 63.572 30.940 1.00 19.57 ? 302 PRO A CG 1 ATOM 2363 C CD . PRO A 1 302 ? 18.126 62.884 30.155 1.00 18.26 ? 302 PRO A CD 1 ATOM 2364 N N . PRO A 1 303 ? 22.238 60.987 29.304 1.00 16.56 ? 303 PRO A N 1 ATOM 2365 C CA . PRO A 1 303 ? 22.944 59.838 29.862 1.00 16.77 ? 303 PRO A CA 1 ATOM 2366 C C . PRO A 1 303 ? 22.908 59.967 31.367 1.00 18.54 ? 303 PRO A C 1 ATOM 2367 O O . PRO A 1 303 ? 22.834 61.093 31.879 1.00 18.49 ? 303 PRO A O 1 ATOM 2368 C CB . PRO A 1 303 ? 24.402 60.032 29.406 1.00 16.65 ? 303 PRO A CB 1 ATOM 2369 C CG . PRO A 1 303 ? 24.398 61.186 28.485 1.00 17.64 ? 303 PRO A CG 1 ATOM 2370 C CD . PRO A 1 303 ? 23.140 61.950 28.644 1.00 17.25 ? 303 PRO A CD 1 ATOM 2371 N N . ARG A 1 304 ? 22.961 58.833 32.050 1.00 18.69 ? 304 ARG A N 1 ATOM 2372 C CA . ARG A 1 304 ? 23.150 58.825 33.494 1.00 20.77 ? 304 ARG A CA 1 ATOM 2373 C C . ARG A 1 304 ? 24.372 58.007 33.857 1.00 17.99 ? 304 ARG A C 1 ATOM 2374 O O . ARG A 1 304 ? 24.607 56.930 33.261 1.00 17.74 ? 304 ARG A O 1 ATOM 2375 C CB . ARG A 1 304 ? 21.913 58.230 34.171 1.00 21.23 ? 304 ARG A CB 1 ATOM 2376 C CG . ARG A 1 304 ? 20.684 59.124 34.061 1.00 25.38 ? 304 ARG A CG 1 ATOM 2377 C CD . ARG A 1 304 ? 19.444 58.524 34.682 1.00 25.80 ? 304 ARG A CD 1 ATOM 2378 N NE . ARG A 1 304 ? 18.774 57.593 33.770 1.00 34.89 ? 304 ARG A NE 1 ATOM 2379 C CZ . ARG A 1 304 ? 17.742 56.820 34.106 1.00 38.38 ? 304 ARG A CZ 1 ATOM 2380 N NH1 . ARG A 1 304 ? 17.241 56.858 35.337 1.00 40.66 ? 304 ARG A NH1 1 ATOM 2381 N NH2 . ARG A 1 304 ? 17.200 56.008 33.206 1.00 39.98 ? 304 ARG A NH2 1 ATOM 2382 N N . THR A 1 305 ? 25.159 58.515 34.805 1.00 17.83 ? 305 THR A N 1 ATOM 2383 C CA . THR A 1 305 ? 26.324 57.812 35.319 1.00 17.32 ? 305 THR A CA 1 ATOM 2384 C C . THR A 1 305 ? 25.951 56.391 35.756 1.00 16.64 ? 305 THR A C 1 ATOM 2385 O O . THR A 1 305 ? 24.913 56.197 36.429 1.00 17.05 ? 305 THR A O 1 ATOM 2386 C CB . THR A 1 305 ? 26.951 58.609 36.491 1.00 17.70 ? 305 THR A CB 1 ATOM 2387 O OG1 . THR A 1 305 ? 27.517 59.827 35.972 1.00 21.41 ? 305 THR A OG1 1 ATOM 2388 C CG2 . THR A 1 305 ? 28.107 57.878 37.070 1.00 18.81 ? 305 THR A CG2 1 ATOM 2389 N N . ILE A 1 306 ? 26.727 55.397 35.346 1.00 15.68 ? 306 ILE A N 1 ATOM 2390 C CA . ILE A 1 306 ? 26.428 54.016 35.725 1.00 15.45 ? 306 ILE A CA 1 ATOM 2391 C C . ILE A 1 306 ? 26.848 53.791 37.172 1.00 16.32 ? 306 ILE A C 1 ATOM 2392 O O . ILE A 1 306 ? 27.948 54.153 37.581 1.00 16.92 ? 306 ILE A O 1 ATOM 2393 C CB . ILE A 1 306 ? 27.095 53.015 34.744 1.00 15.11 ? 306 ILE A CB 1 ATOM 2394 C CG1 . ILE A 1 306 ? 26.724 53.336 33.279 1.00 13.79 ? 306 ILE A CG1 1 ATOM 2395 C CG2 . ILE A 1 306 ? 26.724 51.541 35.099 1.00 14.78 ? 306 ILE A CG2 1 ATOM 2396 C CD1 . ILE A 1 306 ? 25.239 53.280 32.931 1.00 14.56 ? 306 ILE A CD1 1 ATOM 2397 N N . SER A 1 307 ? 25.919 53.207 37.942 1.00 18.30 ? 307 SER A N 1 ATOM 2398 C CA . SER A 1 307 ? 26.114 52.912 39.365 1.00 18.86 ? 307 SER A CA 1 ATOM 2399 C C . SER A 1 307 ? 25.627 51.488 39.601 1.00 19.90 ? 307 SER A C 1 ATOM 2400 O O . SER A 1 307 ? 24.871 50.933 38.778 1.00 18.68 ? 307 SER A O 1 ATOM 2401 C CB . SER A 1 307 ? 25.224 53.831 40.211 1.00 18.61 ? 307 SER A CB 1 ATOM 2402 O OG . SER A 1 307 ? 23.849 53.520 40.031 1.00 18.08 ? 307 SER A OG 1 ATOM 2403 N N . ASP A 1 308 ? 25.951 50.932 40.765 1.00 21.48 ? 308 ASP A N 1 ATOM 2404 C CA . ASP A 1 308 ? 25.391 49.624 41.129 1.00 22.87 ? 308 ASP A CA 1 ATOM 2405 C C . ASP A 1 308 ? 23.854 49.569 41.157 1.00 22.18 ? 308 ASP A C 1 ATOM 2406 O O . ASP A 1 308 ? 23.275 48.516 40.880 1.00 21.16 ? 308 ASP A O 1 ATOM 2407 C CB . ASP A 1 308 ? 25.951 49.163 42.465 1.00 24.59 ? 308 ASP A CB 1 ATOM 2408 C CG . ASP A 1 308 ? 27.455 49.060 42.465 1.00 27.09 ? 308 ASP A CG 1 ATOM 2409 O OD1 . ASP A 1 308 ? 28.072 48.839 41.393 1.00 31.96 ? 308 ASP A OD1 1 ATOM 2410 O OD2 . ASP A 1 308 ? 28.122 49.190 43.513 1.00 34.20 ? 308 ASP A OD2 1 ATOM 2411 N N . GLN A 1 309 ? 23.194 50.693 41.431 1.00 21.26 ? 309 GLN A N 1 ATOM 2412 C CA A GLN A 1 309 ? 21.718 50.748 41.534 0.50 20.94 ? 309 GLN A CA 1 ATOM 2413 C CA B GLN A 1 309 ? 21.748 50.732 41.547 0.50 21.45 ? 309 GLN A CA 1 ATOM 2414 C C . GLN A 1 309 ? 21.008 50.899 40.209 1.00 21.13 ? 309 GLN A C 1 ATOM 2415 O O . GLN A 1 309 ? 19.776 50.682 40.118 1.00 21.81 ? 309 GLN A O 1 ATOM 2416 C CB A GLN A 1 309 ? 21.216 51.879 42.452 0.50 20.24 ? 309 GLN A CB 1 ATOM 2417 C CB B GLN A 1 309 ? 21.405 51.802 42.581 0.50 21.46 ? 309 GLN A CB 1 ATOM 2418 C CG A GLN A 1 309 ? 21.633 51.746 43.906 0.50 18.55 ? 309 GLN A CG 1 ATOM 2419 C CG B GLN A 1 309 ? 20.266 52.713 42.322 0.50 21.17 ? 309 GLN A CG 1 ATOM 2420 C CD A GLN A 1 309 ? 23.111 51.978 44.067 0.50 16.65 ? 309 GLN A CD 1 ATOM 2421 C CD B GLN A 1 309 ? 20.242 53.836 43.334 0.50 19.16 ? 309 GLN A CD 1 ATOM 2422 O OE1 A GLN A 1 309 ? 23.653 52.928 43.485 0.50 15.11 ? 309 GLN A OE1 1 ATOM 2423 O OE1 B GLN A 1 309 ? 20.820 53.701 44.415 0.50 20.06 ? 309 GLN A OE1 1 ATOM 2424 N NE2 A GLN A 1 309 ? 23.778 51.102 44.813 0.50 17.08 ? 309 GLN A NE2 1 ATOM 2425 N NE2 B GLN A 1 309 ? 19.590 54.938 42.998 0.50 19.33 ? 309 GLN A NE2 1 ATOM 2426 N N . ASN A 1 310 ? 21.753 51.284 39.169 1.00 19.96 ? 310 ASN A N 1 ATOM 2427 C CA . ASN A 1 310 ? 21.123 51.409 37.868 1.00 18.16 ? 310 ASN A CA 1 ATOM 2428 C C . ASN A 1 310 ? 21.722 50.466 36.811 1.00 17.07 ? 310 ASN A C 1 ATOM 2429 O O . ASN A 1 310 ? 21.158 50.354 35.742 1.00 16.76 ? 310 ASN A O 1 ATOM 2430 C CB . ASN A 1 310 ? 21.088 52.864 37.374 1.00 18.30 ? 310 ASN A CB 1 ATOM 2431 C CG . ASN A 1 310 ? 22.478 53.412 37.037 1.00 17.33 ? 310 ASN A CG 1 ATOM 2432 O OD1 . ASN A 1 310 ? 23.442 52.665 36.855 1.00 18.12 ? 310 ASN A OD1 1 ATOM 2433 N ND2 . ASN A 1 310 ? 22.566 54.731 36.970 1.00 19.32 ? 310 ASN A ND2 1 ATOM 2434 N N . VAL A 1 311 ? 22.820 49.806 37.132 1.00 16.06 ? 311 VAL A N 1 ATOM 2435 C CA . VAL A 1 311 ? 23.563 49.087 36.058 1.00 16.51 ? 311 VAL A CA 1 ATOM 2436 C C . VAL A 1 311 ? 22.701 47.980 35.432 1.00 17.75 ? 311 VAL A C 1 ATOM 2437 O O . VAL A 1 311 ? 22.812 47.712 34.233 1.00 17.30 ? 311 VAL A O 1 ATOM 2438 C CB . VAL A 1 311 ? 24.933 48.576 36.514 1.00 16.56 ? 311 VAL A CB 1 ATOM 2439 C CG1 . VAL A 1 311 ? 24.812 47.486 37.586 1.00 18.24 ? 311 VAL A CG1 1 ATOM 2440 C CG2 . VAL A 1 311 ? 25.784 48.066 35.292 1.00 16.93 ? 311 VAL A CG2 1 ATOM 2441 N N . ALA A 1 312 ? 21.843 47.317 36.220 1.00 17.28 ? 312 ALA A N 1 ATOM 2442 C CA . ALA A 1 312 ? 21.018 46.244 35.647 1.00 17.29 ? 312 ALA A CA 1 ATOM 2443 C C . ALA A 1 312 ? 20.044 46.800 34.641 1.00 17.98 ? 312 ALA A C 1 ATOM 2444 O O . ALA A 1 312 ? 19.911 46.238 33.549 1.00 18.43 ? 312 ALA A O 1 ATOM 2445 C CB . ALA A 1 312 ? 20.279 45.447 36.751 1.00 17.86 ? 312 ALA A CB 1 ATOM 2446 N N . ALA A 1 313 ? 19.364 47.895 34.973 1.00 16.66 ? 313 ALA A N 1 ATOM 2447 C CA . ALA A 1 313 ? 18.398 48.522 34.091 1.00 17.99 ? 313 ALA A CA 1 ATOM 2448 C C . ALA A 1 313 ? 19.102 49.115 32.869 1.00 17.57 ? 313 ALA A C 1 ATOM 2449 O O . ALA A 1 313 ? 18.601 49.010 31.766 1.00 17.49 ? 313 ALA A O 1 ATOM 2450 C CB . ALA A 1 313 ? 17.614 49.617 34.828 1.00 18.19 ? 313 ALA A CB 1 ATOM 2451 N N . ARG A 1 314 ? 20.231 49.776 33.095 1.00 17.41 ? 314 ARG A N 1 ATOM 2452 C CA . ARG A 1 314 ? 21.001 50.375 31.991 1.00 16.53 ? 314 ARG A CA 1 ATOM 2453 C C . ARG A 1 314 ? 21.487 49.284 31.041 1.00 15.57 ? 314 ARG A C 1 ATOM 2454 O O . ARG A 1 314 ? 21.365 49.454 29.821 1.00 15.66 ? 314 ARG A O 1 ATOM 2455 C CB . ARG A 1 314 ? 22.174 51.166 32.559 1.00 15.65 ? 314 ARG A CB 1 ATOM 2456 C CG . ARG A 1 314 ? 21.780 52.353 33.425 1.00 17.10 ? 314 ARG A CG 1 ATOM 2457 C CD . ARG A 1 314 ? 21.540 53.615 32.658 1.00 21.05 ? 314 ARG A CD 1 ATOM 2458 N NE . ARG A 1 314 ? 20.187 53.655 32.155 1.00 22.63 ? 314 ARG A NE 1 ATOM 2459 C CZ . ARG A 1 314 ? 19.709 54.559 31.318 1.00 22.42 ? 314 ARG A CZ 1 ATOM 2460 N NH1 . ARG A 1 314 ? 20.497 55.530 30.837 1.00 24.30 ? 314 ARG A NH1 1 ATOM 2461 N NH2 . ARG A 1 314 ? 18.429 54.509 30.963 1.00 23.79 ? 314 ARG A NH2 1 ATOM 2462 N N . SER A 1 315 ? 22.008 48.193 31.596 1.00 14.96 ? 315 SER A N 1 ATOM 2463 C CA . SER A 1 315 ? 22.469 47.038 30.794 1.00 15.74 ? 315 SER A CA 1 ATOM 2464 C C . SER A 1 315 ? 21.335 46.411 30.008 1.00 16.99 ? 315 SER A C 1 ATOM 2465 O O . SER A 1 315 ? 21.521 46.017 28.854 1.00 17.82 ? 315 SER A O 1 ATOM 2466 C CB . SER A 1 315 ? 23.124 45.991 31.673 1.00 15.91 ? 315 SER A CB 1 ATOM 2467 O OG . SER A 1 315 ? 24.302 46.476 32.265 1.00 16.19 ? 315 SER A OG 1 ATOM 2468 N N . ASP A 1 316 ? 20.161 46.268 30.623 1.00 17.01 ? 316 ASP A N 1 ATOM 2469 C CA A ASP A 1 316 ? 19.051 45.722 29.886 0.50 17.30 ? 316 ASP A CA 1 ATOM 2470 C CA B ASP A 1 316 ? 18.921 45.820 29.943 0.50 17.67 ? 316 ASP A CA 1 ATOM 2471 C C . ASP A 1 316 ? 18.730 46.580 28.654 1.00 17.37 ? 316 ASP A C 1 ATOM 2472 O O . ASP A 1 316 ? 18.528 46.014 27.569 1.00 16.91 ? 316 ASP A O 1 ATOM 2473 C CB A ASP A 1 316 ? 17.861 45.587 30.814 0.50 17.14 ? 316 ASP A CB 1 ATOM 2474 C CB B ASP A 1 316 ? 17.663 46.175 30.764 0.50 18.38 ? 316 ASP A CB 1 ATOM 2475 C CG A ASP A 1 316 ? 16.989 44.414 30.474 0.50 18.12 ? 316 ASP A CG 1 ATOM 2476 C CG B ASP A 1 316 ? 17.394 45.244 31.921 0.50 18.49 ? 316 ASP A CG 1 ATOM 2477 O OD1 A ASP A 1 316 ? 17.519 43.356 30.069 0.50 18.05 ? 316 ASP A OD1 1 ATOM 2478 O OD1 B ASP A 1 316 ? 18.042 44.191 32.009 0.50 19.69 ? 316 ASP A OD1 1 ATOM 2479 O OD2 A ASP A 1 316 ? 15.757 44.474 30.613 0.50 20.07 ? 316 ASP A OD2 1 ATOM 2480 O OD2 B ASP A 1 316 ? 16.520 45.507 32.790 0.50 20.06 ? 316 ASP A OD2 1 ATOM 2481 N N . LEU A 1 317 ? 18.716 47.906 28.797 1.00 16.68 ? 317 LEU A N 1 ATOM 2482 C CA . LEU A 1 317 ? 18.421 48.808 27.687 1.00 16.58 ? 317 LEU A CA 1 ATOM 2483 C C . LEU A 1 317 ? 19.482 48.707 26.590 1.00 14.64 ? 317 LEU A C 1 ATOM 2484 O O . LEU A 1 317 ? 19.136 48.643 25.419 1.00 15.22 ? 317 LEU A O 1 ATOM 2485 C CB . LEU A 1 317 ? 18.348 50.270 28.157 1.00 17.61 ? 317 LEU A CB 1 ATOM 2486 C CG . LEU A 1 317 ? 16.980 50.822 28.555 1.00 21.64 ? 317 LEU A CG 1 ATOM 2487 C CD1 . LEU A 1 317 ? 17.168 52.146 29.292 1.00 25.26 ? 317 LEU A CD1 1 ATOM 2488 C CD2 . LEU A 1 317 ? 16.046 50.984 27.358 1.00 24.95 ? 317 LEU A CD2 1 ATOM 2489 N N . LEU A 1 318 ? 20.742 48.638 27.007 1.00 13.93 ? 318 LEU A N 1 ATOM 2490 C CA . LEU A 1 318 ? 21.871 48.643 26.049 1.00 13.10 ? 318 LEU A CA 1 ATOM 2491 C C . LEU A 1 318 ? 21.961 47.317 25.311 1.00 13.44 ? 318 LEU A C 1 ATOM 2492 O O . LEU A 1 318 ? 22.087 47.292 24.066 1.00 13.47 ? 318 LEU A O 1 ATOM 2493 C CB . LEU A 1 318 ? 23.175 48.965 26.757 1.00 13.30 ? 318 LEU A CB 1 ATOM 2494 C CG . LEU A 1 318 ? 24.413 49.087 25.837 1.00 13.39 ? 318 LEU A CG 1 ATOM 2495 C CD1 . LEU A 1 318 ? 24.225 50.175 24.759 1.00 15.22 ? 318 LEU A CD1 1 ATOM 2496 C CD2 . LEU A 1 318 ? 25.641 49.364 26.686 1.00 14.76 ? 318 LEU A CD2 1 ATOM 2497 N N . VAL A 1 319 ? 21.848 46.203 26.034 1.00 12.82 ? 319 VAL A N 1 ATOM 2498 C CA . VAL A 1 319 ? 21.926 44.883 25.403 1.00 12.63 ? 319 VAL A CA 1 ATOM 2499 C C . VAL A 1 319 ? 20.768 44.712 24.434 1.00 12.59 ? 319 VAL A C 1 ATOM 2500 O O . VAL A 1 319 ? 20.940 44.117 23.374 1.00 12.86 ? 319 VAL A O 1 ATOM 2501 C CB . VAL A 1 319 ? 21.957 43.733 26.448 1.00 13.56 ? 319 VAL A CB 1 ATOM 2502 C CG1 . VAL A 1 319 ? 21.808 42.361 25.769 1.00 13.48 ? 319 VAL A CG1 1 ATOM 2503 C CG2 . VAL A 1 319 ? 23.243 43.788 27.244 1.00 13.63 ? 319 VAL A CG2 1 ATOM 2504 N N . ASP A 1 320 ? 19.604 45.232 24.811 1.00 13.46 ? 320 ASP A N 1 ATOM 2505 C CA . ASP A 1 320 ? 18.448 45.272 23.926 1.00 13.59 ? 320 ASP A CA 1 ATOM 2506 C C . ASP A 1 320 ? 18.796 45.909 22.586 1.00 13.01 ? 320 ASP A C 1 ATOM 2507 O O . ASP A 1 320 ? 18.531 45.333 21.531 1.00 12.18 ? 320 ASP A O 1 ATOM 2508 C CB . ASP A 1 320 ? 17.294 46.030 24.584 1.00 15.12 ? 320 ASP A CB 1 ATOM 2509 C CG . ASP A 1 320 ? 16.009 45.945 23.784 1.00 15.09 ? 320 ASP A CG 1 ATOM 2510 O OD1 . ASP A 1 320 ? 15.551 44.815 23.512 1.00 18.93 ? 320 ASP A OD1 1 ATOM 2511 O OD2 . ASP A 1 320 ? 15.457 47.007 23.428 1.00 17.57 ? 320 ASP A OD2 1 ATOM 2512 N N . GLN A 1 321 ? 19.390 47.098 22.629 1.00 12.31 ? 321 GLN A N 1 ATOM 2513 C CA . GLN A 1 321 ? 19.834 47.768 21.379 1.00 11.77 ? 321 GLN A CA 1 ATOM 2514 C C . GLN A 1 321 ? 20.834 46.914 20.586 1.00 10.14 ? 321 GLN A C 1 ATOM 2515 O O . GLN A 1 321 ? 20.696 46.768 19.384 1.00 11.55 ? 321 GLN A O 1 ATOM 2516 C CB . GLN A 1 321 ? 20.449 49.129 21.707 1.00 11.20 ? 321 GLN A CB 1 ATOM 2517 C CG . GLN A 1 321 ? 19.453 50.154 22.170 1.00 13.33 ? 321 GLN A CG 1 ATOM 2518 C CD . GLN A 1 321 ? 18.380 50.388 21.113 1.00 14.52 ? 321 GLN A CD 1 ATOM 2519 O OE1 . GLN A 1 321 ? 18.672 50.803 19.994 1.00 14.60 ? 321 GLN A OE1 1 ATOM 2520 N NE2 . GLN A 1 321 ? 17.112 50.133 21.468 1.00 14.79 ? 321 GLN A NE2 1 ATOM 2521 N N . TRP A 1 322 ? 21.825 46.384 21.284 1.00 10.36 ? 322 TRP A N 1 ATOM 2522 C CA . TRP A 1 322 ? 22.824 45.554 20.624 1.00 11.37 ? 322 TRP A CA 1 ATOM 2523 C C . TRP A 1 322 ? 22.205 44.357 19.929 1.00 11.90 ? 322 TRP A C 1 ATOM 2524 O O . TRP A 1 322 ? 22.565 44.014 18.794 1.00 11.83 ? 322 TRP A O 1 ATOM 2525 C CB . TRP A 1 322 ? 23.837 45.070 21.628 1.00 11.48 ? 322 TRP A CB 1 ATOM 2526 C CG . TRP A 1 322 ? 24.770 46.135 22.176 1.00 10.79 ? 322 TRP A CG 1 ATOM 2527 C CD1 . TRP A 1 322 ? 24.957 47.417 21.707 1.00 11.67 ? 322 TRP A CD1 1 ATOM 2528 C CD2 . TRP A 1 322 ? 25.660 45.976 23.282 1.00 11.23 ? 322 TRP A CD2 1 ATOM 2529 N NE1 . TRP A 1 322 ? 25.910 48.058 22.476 1.00 12.07 ? 322 TRP A NE1 1 ATOM 2530 C CE2 . TRP A 1 322 ? 26.389 47.190 23.426 1.00 10.94 ? 322 TRP A CE2 1 ATOM 2531 C CE3 . TRP A 1 322 ? 25.963 44.901 24.140 1.00 12.57 ? 322 TRP A CE3 1 ATOM 2532 C CZ2 . TRP A 1 322 ? 27.345 47.382 24.440 1.00 12.60 ? 322 TRP A CZ2 1 ATOM 2533 C CZ3 . TRP A 1 322 ? 26.935 45.085 25.141 1.00 12.21 ? 322 TRP A CZ3 1 ATOM 2534 C CH2 . TRP A 1 322 ? 27.606 46.310 25.277 1.00 13.45 ? 322 TRP A CH2 1 ATOM 2535 N N . LYS A 1 323 ? 21.277 43.672 20.609 1.00 11.55 ? 323 LYS A N 1 ATOM 2536 C CA . LYS A 1 323 ? 20.683 42.469 20.007 1.00 12.45 ? 323 LYS A CA 1 ATOM 2537 C C . LYS A 1 323 ? 19.810 42.827 18.828 1.00 12.14 ? 323 LYS A C 1 ATOM 2538 O O . LYS A 1 323 ? 19.717 42.071 17.872 1.00 12.38 ? 323 LYS A O 1 ATOM 2539 C CB . LYS A 1 323 ? 19.922 41.635 21.068 1.00 13.20 ? 323 LYS A CB 1 ATOM 2540 C CG . LYS A 1 323 ? 20.879 40.871 21.964 1.00 14.11 ? 323 LYS A CG 1 ATOM 2541 C CD . LYS A 1 323 ? 20.163 40.084 23.051 1.00 14.06 ? 323 LYS A CD 1 ATOM 2542 C CE . LYS A 1 323 ? 21.170 39.237 23.746 1.00 15.71 ? 323 LYS A CE 1 ATOM 2543 N NZ . LYS A 1 323 ? 20.485 38.531 24.873 1.00 19.90 ? 323 LYS A NZ 1 ATOM 2544 N N . LYS A 1 324 ? 19.188 43.987 18.856 1.00 10.93 ? 324 LYS A N 1 ATOM 2545 C CA . LYS A 1 324 ? 18.472 44.473 17.666 1.00 11.17 ? 324 LYS A CA 1 ATOM 2546 C C . LYS A 1 324 ? 19.417 44.743 16.492 1.00 11.75 ? 324 LYS A C 1 ATOM 2547 O O . LYS A 1 324 ? 19.171 44.308 15.375 1.00 11.69 ? 324 LYS A O 1 ATOM 2548 C CB . LYS A 1 324 ? 17.666 45.729 17.994 1.00 11.12 ? 324 LYS A CB 1 ATOM 2549 C CG . LYS A 1 324 ? 16.424 45.387 18.815 1.00 11.66 ? 324 LYS A CG 1 ATOM 2550 C CD . LYS A 1 324 ? 15.792 46.613 19.372 1.00 13.11 ? 324 LYS A CD 1 ATOM 2551 C CE . LYS A 1 324 ? 14.512 46.200 20.135 1.00 14.26 ? 324 LYS A CE 1 ATOM 2552 N NZ . LYS A 1 324 ? 13.919 47.337 20.892 1.00 16.40 ? 324 LYS A NZ 1 ATOM 2553 N N . LYS A 1 325 ? 20.495 45.481 16.751 1.00 10.76 ? 325 LYS A N 1 ATOM 2554 C CA . LYS A 1 325 ? 21.494 45.706 15.696 1.00 10.26 ? 325 LYS A CA 1 ATOM 2555 C C . LYS A 1 325 ? 22.011 44.378 15.150 1.00 9.60 ? 325 LYS A C 1 ATOM 2556 O O . LYS A 1 325 ? 22.183 44.213 13.941 1.00 9.70 ? 325 LYS A O 1 ATOM 2557 C CB . LYS A 1 325 ? 22.651 46.540 16.226 1.00 10.18 ? 325 LYS A CB 1 ATOM 2558 C CG . LYS A 1 325 ? 23.549 47.100 15.096 1.00 9.71 ? 325 LYS A CG 1 ATOM 2559 C CD . LYS A 1 325 ? 24.655 47.969 15.678 1.00 11.39 ? 325 LYS A CD 1 ATOM 2560 C CE . LYS A 1 325 ? 25.391 48.705 14.548 1.00 11.47 ? 325 LYS A CE 1 ATOM 2561 N NZ . LYS A 1 325 ? 26.611 49.375 15.139 1.00 12.40 ? 325 LYS A NZ 1 ATOM 2562 N N . ALA A 1 326 ? 22.257 43.405 16.038 1.00 10.02 ? 326 ALA A N 1 ATOM 2563 C CA . ALA A 1 326 ? 22.822 42.108 15.625 1.00 10.73 ? 326 ALA A CA 1 ATOM 2564 C C . ALA A 1 326 ? 21.891 41.347 14.681 1.00 10.83 ? 326 ALA A C 1 ATOM 2565 O O . ALA A 1 326 ? 22.331 40.491 13.912 1.00 11.59 ? 326 ALA A O 1 ATOM 2566 C CB . ALA A 1 326 ? 23.131 41.258 16.834 1.00 10.82 ? 326 ALA A CB 1 ATOM 2567 N N . GLU A 1 327 ? 20.600 41.659 14.751 1.00 11.35 ? 327 GLU A N 1 ATOM 2568 C CA . GLU A 1 327 ? 19.627 41.009 13.850 1.00 13.48 ? 327 GLU A CA 1 ATOM 2569 C C . GLU A 1 327 ? 19.872 41.335 12.386 1.00 12.78 ? 327 GLU A C 1 ATOM 2570 O O . GLU A 1 327 ? 19.405 40.619 11.478 1.00 13.70 ? 327 GLU A O 1 ATOM 2571 C CB . GLU A 1 327 ? 18.204 41.423 14.203 1.00 14.57 ? 327 GLU A CB 1 ATOM 2572 C CG . GLU A 1 327 ? 17.604 40.629 15.332 1.00 18.18 ? 327 GLU A CG 1 ATOM 2573 C CD . GLU A 1 327 ? 17.585 39.118 15.064 1.00 17.98 ? 327 GLU A CD 1 ATOM 2574 O OE1 . GLU A 1 327 ? 16.911 38.658 14.124 1.00 23.00 ? 327 GLU A OE1 1 ATOM 2575 O OE2 . GLU A 1 327 ? 18.269 38.401 15.781 1.00 21.64 ? 327 GLU A OE2 1 ATOM 2576 N N . LEU A 1 328 ? 20.586 42.438 12.141 1.00 11.75 ? 328 LEU A N 1 ATOM 2577 C CA . LEU A 1 328 ? 20.819 42.920 10.777 1.00 11.06 ? 328 LEU A CA 1 ATOM 2578 C C . LEU A 1 328 ? 22.010 42.248 10.114 1.00 11.11 ? 328 LEU A C 1 ATOM 2579 O O . LEU A 1 328 ? 22.290 42.515 8.947 1.00 11.48 ? 328 LEU A O 1 ATOM 2580 C CB . LEU A 1 328 ? 20.997 44.445 10.787 1.00 11.08 ? 328 LEU A CB 1 ATOM 2581 C CG . LEU A 1 328 ? 19.907 45.234 11.487 1.00 10.50 ? 328 LEU A CG 1 ATOM 2582 C CD1 . LEU A 1 328 ? 20.149 46.726 11.327 1.00 12.13 ? 328 LEU A CD1 1 ATOM 2583 C CD2 . LEU A 1 328 ? 18.501 44.871 10.990 1.00 12.54 ? 328 LEU A CD2 1 ATOM 2584 N N . TYR A 1 329 ? 22.740 41.420 10.853 1.00 10.06 ? 329 TYR A N 1 ATOM 2585 C CA . TYR A 1 329 ? 23.991 40.823 10.393 1.00 9.71 ? 329 TYR A CA 1 ATOM 2586 C C . TYR A 1 329 ? 23.967 39.307 10.601 1.00 11.18 ? 329 TYR A C 1 ATOM 2587 O O . TYR A 1 329 ? 23.118 38.784 11.345 1.00 13.03 ? 329 TYR A O 1 ATOM 2588 C CB . TYR A 1 329 ? 25.191 41.437 11.160 1.00 10.99 ? 329 TYR A CB 1 ATOM 2589 C CG . TYR A 1 329 ? 25.378 42.902 10.808 1.00 10.25 ? 329 TYR A CG 1 ATOM 2590 C CD1 . TYR A 1 329 ? 26.119 43.256 9.699 1.00 11.27 ? 329 TYR A CD1 1 ATOM 2591 C CD2 . TYR A 1 329 ? 24.803 43.913 11.579 1.00 11.87 ? 329 TYR A CD2 1 ATOM 2592 C CE1 . TYR A 1 329 ? 26.274 44.594 9.326 1.00 11.12 ? 329 TYR A CE1 1 ATOM 2593 C CE2 . TYR A 1 329 ? 24.953 45.251 11.241 1.00 12.01 ? 329 TYR A CE2 1 ATOM 2594 C CZ . TYR A 1 329 ? 25.679 45.568 10.098 1.00 10.38 ? 329 TYR A CZ 1 ATOM 2595 O OH . TYR A 1 329 ? 25.783 46.917 9.763 1.00 11.39 ? 329 TYR A OH 1 ATOM 2596 N N . ARG A 1 330 ? 24.886 38.599 9.967 1.00 10.76 ? 330 ARG A N 1 ATOM 2597 C CA . ARG A 1 330 ? 24.824 37.137 9.870 1.00 11.85 ? 330 ARG A CA 1 ATOM 2598 C C . ARG A 1 330 ? 25.607 36.381 10.915 1.00 13.05 ? 330 ARG A C 1 ATOM 2599 O O . ARG A 1 330 ? 25.408 35.160 11.049 1.00 14.95 ? 330 ARG A O 1 ATOM 2600 C CB . ARG A 1 330 ? 25.265 36.680 8.478 1.00 12.08 ? 330 ARG A CB 1 ATOM 2601 C CG . ARG A 1 330 ? 24.290 37.093 7.399 1.00 12.07 ? 330 ARG A CG 1 ATOM 2602 C CD . ARG A 1 330 ? 24.633 36.553 6.034 1.00 13.13 ? 330 ARG A CD 1 ATOM 2603 N NE . ARG A 1 330 ? 23.676 37.108 5.095 1.00 14.95 ? 330 ARG A NE 1 ATOM 2604 C CZ . ARG A 1 330 ? 23.347 36.584 3.922 1.00 17.95 ? 330 ARG A CZ 1 ATOM 2605 N NH1 . ARG A 1 330 ? 23.923 35.464 3.484 1.00 18.86 ? 330 ARG A NH1 1 ATOM 2606 N NH2 . ARG A 1 330 ? 22.439 37.217 3.185 1.00 17.58 ? 330 ARG A NH2 1 ATOM 2607 N N . THR A 1 331 ? 26.531 37.029 11.610 1.00 12.52 ? 331 THR A N 1 ATOM 2608 C CA . THR A 1 331 ? 27.304 36.303 12.630 1.00 11.86 ? 331 THR A CA 1 ATOM 2609 C C . THR A 1 331 ? 26.894 36.699 14.037 1.00 12.52 ? 331 THR A C 1 ATOM 2610 O O . THR A 1 331 ? 26.085 37.587 14.213 1.00 13.51 ? 331 THR A O 1 ATOM 2611 C CB . THR A 1 331 ? 28.821 36.492 12.483 1.00 12.38 ? 331 THR A CB 1 ATOM 2612 O OG1 . THR A 1 331 ? 29.223 37.790 12.980 1.00 12.40 ? 331 THR A OG1 1 ATOM 2613 C CG2 . THR A 1 331 ? 29.289 36.361 10.998 1.00 13.39 ? 331 THR A CG2 1 ATOM 2614 N N . ASN A 1 332 ? 27.535 36.077 15.030 1.00 12.52 ? 332 ASN A N 1 ATOM 2615 C CA . ASN A 1 332 ? 27.330 36.428 16.439 1.00 12.74 ? 332 ASN A CA 1 ATOM 2616 C C . ASN A 1 332 ? 28.403 37.390 16.950 1.00 11.84 ? 332 ASN A C 1 ATOM 2617 O O . ASN A 1 332 ? 28.673 37.453 18.150 1.00 12.75 ? 332 ASN A O 1 ATOM 2618 C CB . ASN A 1 332 ? 27.281 35.149 17.319 1.00 14.14 ? 332 ASN A CB 1 ATOM 2619 C CG . ASN A 1 332 ? 28.626 34.454 17.446 1.00 17.48 ? 332 ASN A CG 1 ATOM 2620 O OD1 . ASN A 1 332 ? 29.437 34.455 16.528 1.00 18.36 ? 332 ASN A OD1 1 ATOM 2621 N ND2 . ASN A 1 332 ? 28.868 33.833 18.612 1.00 21.54 ? 332 ASN A ND2 1 ATOM 2622 N N . VAL A 1 333 ? 29.004 38.150 16.022 1.00 11.35 ? 333 VAL A N 1 ATOM 2623 C CA . VAL A 1 333 ? 30.061 39.098 16.364 1.00 11.17 ? 333 VAL A CA 1 ATOM 2624 C C . VAL A 1 333 ? 29.529 40.453 15.938 1.00 10.46 ? 333 VAL A C 1 ATOM 2625 O O . VAL A 1 333 ? 29.184 40.624 14.772 1.00 11.59 ? 333 VAL A O 1 ATOM 2626 C CB . VAL A 1 333 ? 31.361 38.791 15.596 1.00 11.72 ? 333 VAL A CB 1 ATOM 2627 C CG1 . VAL A 1 333 ? 32.472 39.787 16.011 1.00 11.68 ? 333 VAL A CG1 1 ATOM 2628 C CG2 . VAL A 1 333 ? 31.797 37.343 15.817 1.00 13.61 ? 333 VAL A CG2 1 ATOM 2629 N N . LEU A 1 334 ? 29.440 41.421 16.855 1.00 9.57 ? 334 LEU A N 1 ATOM 2630 C CA . LEU A 1 334 ? 28.805 42.693 16.608 1.00 9.71 ? 334 LEU A CA 1 ATOM 2631 C C . LEU A 1 334 ? 29.800 43.846 16.766 1.00 9.45 ? 334 LEU A C 1 ATOM 2632 O O . LEU A 1 334 ? 30.519 43.945 17.759 1.00 10.06 ? 334 LEU A O 1 ATOM 2633 C CB . LEU A 1 334 ? 27.673 42.895 17.622 1.00 9.63 ? 334 LEU A CB 1 ATOM 2634 C CG . LEU A 1 334 ? 26.820 44.149 17.417 1.00 10.58 ? 334 LEU A CG 1 ATOM 2635 C CD1 . LEU A 1 334 ? 26.020 44.075 16.100 1.00 11.90 ? 334 LEU A CD1 1 ATOM 2636 C CD2 . LEU A 1 334 ? 25.872 44.344 18.613 1.00 11.04 ? 334 LEU A CD2 1 ATOM 2637 N N . LEU A 1 335 ? 29.780 44.757 15.796 1.00 8.36 ? 335 LEU A N 1 ATOM 2638 C CA . LEU A 1 335 ? 30.620 45.959 15.820 1.00 8.90 ? 335 LEU A CA 1 ATOM 2639 C C . LEU A 1 335 ? 29.831 47.152 16.359 1.00 8.18 ? 335 LEU A C 1 ATOM 2640 O O . LEU A 1 335 ? 28.786 47.507 15.799 1.00 9.31 ? 335 LEU A O 1 ATOM 2641 C CB . LEU A 1 335 ? 31.068 46.296 14.385 1.00 9.52 ? 335 LEU A CB 1 ATOM 2642 C CG . LEU A 1 335 ? 31.946 47.556 14.289 1.00 8.78 ? 335 LEU A CG 1 ATOM 2643 C CD1 . LEU A 1 335 ? 33.242 47.442 15.050 1.00 11.17 ? 335 LEU A CD1 1 ATOM 2644 C CD2 . LEU A 1 335 ? 32.197 47.861 12.828 1.00 12.52 ? 335 LEU A CD2 1 ATOM 2645 N N . ILE A 1 336 ? 30.329 47.767 17.433 1.00 8.68 ? 336 ILE A N 1 ATOM 2646 C CA . ILE A 1 336 ? 29.738 48.960 18.023 1.00 8.96 ? 336 ILE A CA 1 ATOM 2647 C C . ILE A 1 336 ? 30.796 50.076 18.038 1.00 7.79 ? 336 ILE A C 1 ATOM 2648 O O . ILE A 1 336 ? 31.575 50.204 18.977 1.00 9.13 ? 336 ILE A O 1 ATOM 2649 C CB . ILE A 1 336 ? 29.194 48.685 19.454 1.00 9.91 ? 336 ILE A CB 1 ATOM 2650 C CG1 . ILE A 1 336 ? 28.157 47.535 19.446 1.00 9.68 ? 336 ILE A CG1 1 ATOM 2651 C CG2 . ILE A 1 336 ? 28.638 49.993 20.044 1.00 9.98 ? 336 ILE A CG2 1 ATOM 2652 C CD1 . ILE A 1 336 ? 26.870 47.866 18.722 1.00 10.71 ? 336 ILE A CD1 1 ATOM 2653 N N . PRO A 1 337 ? 30.834 50.906 17.004 1.00 7.83 ? 337 PRO A N 1 ATOM 2654 C CA . PRO A 1 337 ? 31.705 52.096 17.066 1.00 7.94 ? 337 PRO A CA 1 ATOM 2655 C C . PRO A 1 337 ? 31.315 53.012 18.224 1.00 8.71 ? 337 PRO A C 1 ATOM 2656 O O . PRO A 1 337 ? 30.121 53.127 18.508 1.00 9.54 ? 337 PRO A O 1 ATOM 2657 C CB . PRO A 1 337 ? 31.456 52.776 15.705 1.00 8.58 ? 337 PRO A CB 1 ATOM 2658 C CG . PRO A 1 337 ? 30.974 51.626 14.800 1.00 8.72 ? 337 PRO A CG 1 ATOM 2659 C CD . PRO A 1 337 ? 30.078 50.847 15.736 1.00 8.79 ? 337 PRO A CD 1 ATOM 2660 N N . LEU A 1 338 ? 32.295 53.633 18.871 1.00 8.72 ? 338 LEU A N 1 ATOM 2661 C CA . LEU A 1 338 ? 32.046 54.558 19.979 1.00 8.56 ? 338 LEU A CA 1 ATOM 2662 C C . LEU A 1 338 ? 32.852 55.844 19.743 1.00 8.58 ? 338 LEU A C 1 ATOM 2663 O O . LEU A 1 338 ? 34.004 55.947 20.181 1.00 8.99 ? 338 LEU A O 1 ATOM 2664 C CB . LEU A 1 338 ? 32.388 53.891 21.319 1.00 9.86 ? 338 LEU A CB 1 ATOM 2665 C CG . LEU A 1 338 ? 32.009 54.764 22.518 1.00 10.53 ? 338 LEU A CG 1 ATOM 2666 C CD1 . LEU A 1 338 ? 30.509 54.644 22.832 1.00 12.78 ? 338 LEU A CD1 1 ATOM 2667 C CD2 . LEU A 1 338 ? 32.774 54.293 23.728 1.00 12.49 ? 338 LEU A CD2 1 ATOM 2668 N N . GLY A 1 339 ? 32.237 56.811 19.084 1.00 8.38 ? 339 GLY A N 1 ATOM 2669 C CA . GLY A 1 339 ? 32.968 58.041 18.784 1.00 9.44 ? 339 GLY A CA 1 ATOM 2670 C C . GLY A 1 339 ? 32.150 59.014 17.976 1.00 9.65 ? 339 GLY A C 1 ATOM 2671 O O . GLY A 1 339 ? 30.970 58.776 17.696 1.00 9.95 ? 339 GLY A O 1 ATOM 2672 N N . ASP A 1 340 ? 32.791 60.135 17.599 1.00 8.80 ? 340 ASP A N 1 ATOM 2673 C CA . ASP A 1 340 ? 32.165 61.233 16.892 1.00 9.10 ? 340 ASP A CA 1 ATOM 2674 C C . ASP A 1 340 ? 33.320 62.185 16.525 1.00 8.76 ? 340 ASP A C 1 ATOM 2675 O O . ASP A 1 340 ? 34.489 61.865 16.705 1.00 8.79 ? 340 ASP A O 1 ATOM 2676 C CB . ASP A 1 340 ? 31.128 61.905 17.833 1.00 10.24 ? 340 ASP A CB 1 ATOM 2677 C CG . ASP A 1 340 ? 30.033 62.682 17.133 1.00 11.05 ? 340 ASP A CG 1 ATOM 2678 O OD1 . ASP A 1 340 ? 30.188 63.067 15.935 1.00 13.55 ? 340 ASP A OD1 1 ATOM 2679 O OD2 . ASP A 1 340 ? 28.980 62.976 17.759 1.00 12.87 ? 340 ASP A OD2 1 ATOM 2680 N N . ASP A 1 341 ? 32.957 63.350 16.017 1.00 9.50 ? 341 ASP A N 1 ATOM 2681 C CA . ASP A 1 341 ? 33.941 64.291 15.469 1.00 9.22 ? 341 ASP A CA 1 ATOM 2682 C C . ASP A 1 341 ? 34.802 64.833 16.595 1.00 9.68 ? 341 ASP A C 1 ATOM 2683 O O . ASP A 1 341 ? 34.292 65.308 17.586 1.00 10.22 ? 341 ASP A O 1 ATOM 2684 C CB . ASP A 1 341 ? 33.240 65.438 14.749 1.00 11.40 ? 341 ASP A CB 1 ATOM 2685 C CG . ASP A 1 341 ? 32.694 65.033 13.403 1.00 12.89 ? 341 ASP A CG 1 ATOM 2686 O OD1 . ASP A 1 341 ? 32.759 63.869 13.051 1.00 12.10 ? 341 ASP A OD1 1 ATOM 2687 O OD2 . ASP A 1 341 ? 32.241 65.915 12.700 1.00 18.20 ? 341 ASP A OD2 1 ATOM 2688 N N . PHE A 1 342 ? 36.109 64.760 16.405 1.00 8.53 ? 342 PHE A N 1 ATOM 2689 C CA . PHE A 1 342 ? 37.086 65.316 17.348 1.00 9.06 ? 342 PHE A CA 1 ATOM 2690 C C . PHE A 1 342 ? 36.780 64.914 18.805 1.00 9.46 ? 342 PHE A C 1 ATOM 2691 O O . PHE A 1 342 ? 37.028 65.688 19.759 1.00 11.21 ? 342 PHE A O 1 ATOM 2692 C CB . PHE A 1 342 ? 37.235 66.839 17.161 1.00 9.96 ? 342 PHE A CB 1 ATOM 2693 C CG . PHE A 1 342 ? 37.793 67.229 15.824 1.00 9.89 ? 342 PHE A CG 1 ATOM 2694 C CD1 . PHE A 1 342 ? 39.169 67.198 15.596 1.00 8.49 ? 342 PHE A CD1 1 ATOM 2695 C CD2 . PHE A 1 342 ? 36.948 67.647 14.779 1.00 10.01 ? 342 PHE A CD2 1 ATOM 2696 C CE1 . PHE A 1 342 ? 39.690 67.590 14.376 1.00 8.13 ? 342 PHE A CE1 1 ATOM 2697 C CE2 . PHE A 1 342 ? 37.498 68.015 13.529 1.00 10.74 ? 342 PHE A CE2 1 ATOM 2698 C CZ . PHE A 1 342 ? 38.862 67.998 13.360 1.00 9.79 ? 342 PHE A CZ 1 ATOM 2699 N N . ARG A 1 343 ? 36.360 63.657 18.975 1.00 8.77 ? 343 ARG A N 1 ATOM 2700 C CA . ARG A 1 343 ? 36.161 63.115 20.321 1.00 8.79 ? 343 ARG A CA 1 ATOM 2701 C C . ARG A 1 343 ? 37.464 62.678 20.968 1.00 10.09 ? 343 ARG A C 1 ATOM 2702 O O . ARG A 1 343 ? 38.532 62.612 20.355 1.00 9.38 ? 343 ARG A O 1 ATOM 2703 C CB . ARG A 1 343 ? 35.145 61.968 20.305 1.00 9.29 ? 343 ARG A CB 1 ATOM 2704 C CG . ARG A 1 343 ? 33.723 62.435 20.072 1.00 10.76 ? 343 ARG A CG 1 ATOM 2705 C CD . ARG A 1 343 ? 33.240 63.383 21.159 1.00 11.08 ? 343 ARG A CD 1 ATOM 2706 N NE . ARG A 1 343 ? 31.805 63.646 21.093 1.00 10.85 ? 343 ARG A NE 1 ATOM 2707 C CZ . ARG A 1 343 ? 30.876 62.930 21.733 1.00 10.27 ? 343 ARG A CZ 1 ATOM 2708 N NH1 . ARG A 1 343 ? 31.243 61.896 22.472 1.00 10.41 ? 343 ARG A NH1 1 ATOM 2709 N NH2 . ARG A 1 343 ? 29.607 63.294 21.654 1.00 11.02 ? 343 ARG A NH2 1 ATOM 2710 N N . PHE A 1 344 ? 37.332 62.363 22.253 1.00 10.30 ? 344 PHE A N 1 ATOM 2711 C CA . PHE A 1 344 ? 38.452 61.888 23.071 1.00 10.67 ? 344 PHE A CA 1 ATOM 2712 C C . PHE A 1 344 ? 39.550 62.925 23.215 1.00 11.68 ? 344 PHE A C 1 ATOM 2713 O O . PHE A 1 344 ? 40.737 62.616 23.155 1.00 13.03 ? 344 PHE A O 1 ATOM 2714 C CB . PHE A 1 344 ? 38.900 60.513 22.568 1.00 11.27 ? 344 PHE A CB 1 ATOM 2715 C CG . PHE A 1 344 ? 37.863 59.470 22.781 1.00 10.91 ? 344 PHE A CG 1 ATOM 2716 C CD1 . PHE A 1 344 ? 37.657 58.943 24.068 1.00 12.87 ? 344 PHE A CD1 1 ATOM 2717 C CD2 . PHE A 1 344 ? 37.040 59.046 21.737 1.00 11.43 ? 344 PHE A CD2 1 ATOM 2718 C CE1 . PHE A 1 344 ? 36.669 57.976 24.275 1.00 13.05 ? 344 PHE A CE1 1 ATOM 2719 C CE2 . PHE A 1 344 ? 36.040 58.092 21.941 1.00 11.58 ? 344 PHE A CE2 1 ATOM 2720 C CZ . PHE A 1 344 ? 35.879 57.553 23.229 1.00 12.12 ? 344 PHE A CZ 1 ATOM 2721 N N . LYS A 1 345 ? 39.127 64.170 23.426 1.00 12.53 ? 345 LYS A N 1 ATOM 2722 C CA . LYS A 1 345 ? 40.045 65.287 23.620 1.00 14.77 ? 345 LYS A CA 1 ATOM 2723 C C . LYS A 1 345 ? 40.393 65.355 25.121 1.00 16.27 ? 345 LYS A C 1 ATOM 2724 O O . LYS A 1 345 ? 41.474 64.942 25.532 1.00 19.63 ? 345 LYS A O 1 ATOM 2725 C CB . LYS A 1 345 ? 39.367 66.562 23.099 1.00 15.35 ? 345 LYS A CB 1 ATOM 2726 C CG . LYS A 1 345 ? 40.204 67.806 23.116 1.00 17.40 ? 345 LYS A CG 1 ATOM 2727 C CD . LYS A 1 345 ? 39.436 68.957 22.508 1.00 21.04 ? 345 LYS A CD 1 ATOM 2728 C CE . LYS A 1 345 ? 40.139 70.268 22.750 1.00 23.12 ? 345 LYS A CE 1 ATOM 2729 N NZ . LYS A 1 345 ? 39.331 71.367 22.135 1.00 24.83 ? 345 LYS A NZ 1 ATOM 2730 N N . GLN A 1 346 ? 39.429 65.745 25.932 1.00 15.93 ? 346 GLN A N 1 ATOM 2731 C CA . GLN A 1 346 ? 39.661 66.022 27.348 1.00 17.01 ? 346 GLN A CA 1 ATOM 2732 C C . GLN A 1 346 ? 39.968 64.732 28.138 1.00 16.21 ? 346 GLN A C 1 ATOM 2733 O O . GLN A 1 346 ? 39.346 63.679 27.909 1.00 14.25 ? 346 GLN A O 1 ATOM 2734 C CB . GLN A 1 346 ? 38.426 66.722 27.945 1.00 17.40 ? 346 GLN A CB 1 ATOM 2735 C CG . GLN A 1 346 ? 37.999 68.074 27.300 1.00 21.96 ? 346 GLN A CG 1 ATOM 2736 C CD . GLN A 1 346 ? 36.797 67.953 26.338 1.00 25.50 ? 346 GLN A CD 1 ATOM 2737 O OE1 . GLN A 1 346 ? 36.686 66.986 25.572 1.00 22.26 ? 346 GLN A OE1 1 ATOM 2738 N NE2 . GLN A 1 346 ? 35.898 68.939 26.382 1.00 27.79 ? 346 GLN A NE2 1 ATOM 2739 N N . ASN A 1 347 ? 40.883 64.808 29.104 1.00 16.31 ? 347 ASN A N 1 ATOM 2740 C CA . ASN A 1 347 ? 41.079 63.690 30.044 1.00 16.21 ? 347 ASN A CA 1 ATOM 2741 C C . ASN A 1 347 ? 39.806 63.263 30.743 1.00 14.87 ? 347 ASN A C 1 ATOM 2742 O O . ASN A 1 347 ? 39.533 62.062 30.826 1.00 15.21 ? 347 ASN A O 1 ATOM 2743 C CB . ASN A 1 347 ? 42.121 64.051 31.108 1.00 17.08 ? 347 ASN A CB 1 ATOM 2744 C CG . ASN A 1 347 ? 43.442 64.338 30.501 1.00 21.46 ? 347 ASN A CG 1 ATOM 2745 O OD1 . ASN A 1 347 ? 43.951 65.476 30.561 1.00 28.59 ? 347 ASN A OD1 1 ATOM 2746 N ND2 . ASN A 1 347 ? 44.009 63.339 29.873 1.00 23.24 ? 347 ASN A ND2 1 ATOM 2747 N N . THR A 1 348 ? 38.980 64.236 31.122 1.00 14.56 ? 348 THR A N 1 ATOM 2748 C CA . THR A 1 348 ? 37.704 63.933 31.766 1.00 15.39 ? 348 THR A CA 1 ATOM 2749 C C . THR A 1 348 ? 36.787 63.156 30.833 1.00 15.11 ? 348 THR A C 1 ATOM 2750 O O . THR A 1 348 ? 35.975 62.343 31.292 1.00 14.70 ? 348 THR A O 1 ATOM 2751 C CB . THR A 1 348 ? 36.983 65.213 32.258 1.00 15.67 ? 348 THR A CB 1 ATOM 2752 O OG1 . THR A 1 348 ? 36.854 66.165 31.186 1.00 19.00 ? 348 THR A OG1 1 ATOM 2753 C CG2 . THR A 1 348 ? 37.792 65.938 33.350 1.00 16.87 ? 348 THR A CG2 1 ATOM 2754 N N . GLU A 1 349 ? 36.904 63.383 29.519 1.00 12.88 ? 349 GLU A N 1 ATOM 2755 C CA . GLU A 1 349 ? 36.087 62.655 28.555 1.00 12.68 ? 349 GLU A CA 1 ATOM 2756 C C . GLU A 1 349 ? 36.541 61.196 28.389 1.00 11.45 ? 349 GLU A C 1 ATOM 2757 O O . GLU A 1 349 ? 35.734 60.279 28.367 1.00 11.70 ? 349 GLU A O 1 ATOM 2758 C CB . GLU A 1 349 ? 36.145 63.379 27.202 1.00 12.19 ? 349 GLU A CB 1 ATOM 2759 C CG . GLU A 1 349 ? 35.418 62.628 26.118 1.00 12.20 ? 349 GLU A CG 1 ATOM 2760 C CD . GLU A 1 349 ? 35.640 63.205 24.714 1.00 11.73 ? 349 GLU A CD 1 ATOM 2761 O OE1 . GLU A 1 349 ? 36.339 64.216 24.553 1.00 13.97 ? 349 GLU A OE1 1 ATOM 2762 O OE2 . GLU A 1 349 ? 35.115 62.595 23.795 1.00 13.40 ? 349 GLU A OE2 1 ATOM 2763 N N . TRP A 1 350 ? 37.850 60.988 28.326 1.00 10.99 ? 350 TRP A N 1 ATOM 2764 C CA . TRP A 1 350 ? 38.381 59.631 28.344 1.00 11.13 ? 350 TRP A CA 1 ATOM 2765 C C . TRP A 1 350 ? 37.828 58.871 29.559 1.00 11.89 ? 350 TRP A C 1 ATOM 2766 O O . TRP A 1 350 ? 37.349 57.747 29.441 1.00 12.67 ? 350 TRP A O 1 ATOM 2767 C CB . TRP A 1 350 ? 39.908 59.611 28.374 1.00 11.15 ? 350 TRP A CB 1 ATOM 2768 C CG . TRP A 1 350 ? 40.516 59.820 27.014 1.00 11.42 ? 350 TRP A CG 1 ATOM 2769 C CD1 . TRP A 1 350 ? 40.844 61.007 26.437 1.00 11.84 ? 350 TRP A CD1 1 ATOM 2770 C CD2 . TRP A 1 350 ? 40.829 58.798 26.060 1.00 11.59 ? 350 TRP A CD2 1 ATOM 2771 N NE1 . TRP A 1 350 ? 41.387 60.789 25.184 1.00 10.76 ? 350 TRP A NE1 1 ATOM 2772 C CE2 . TRP A 1 350 ? 41.354 59.447 24.915 1.00 11.04 ? 350 TRP A CE2 1 ATOM 2773 C CE3 . TRP A 1 350 ? 40.716 57.402 26.045 1.00 13.59 ? 350 TRP A CE3 1 ATOM 2774 C CZ2 . TRP A 1 350 ? 41.756 58.749 23.783 1.00 13.10 ? 350 TRP A CZ2 1 ATOM 2775 C CZ3 . TRP A 1 350 ? 41.140 56.714 24.906 1.00 14.18 ? 350 TRP A CZ3 1 ATOM 2776 C CH2 . TRP A 1 350 ? 41.636 57.397 23.802 1.00 12.85 ? 350 TRP A CH2 1 ATOM 2777 N N . ASP A 1 351 ? 37.889 59.507 30.734 1.00 13.38 ? 351 ASP A N 1 ATOM 2778 C CA . ASP A 1 351 ? 37.455 58.870 31.987 1.00 14.28 ? 351 ASP A CA 1 ATOM 2779 C C . ASP A 1 351 ? 35.984 58.555 31.968 1.00 13.35 ? 351 ASP A C 1 ATOM 2780 O O . ASP A 1 351 ? 35.587 57.424 32.326 1.00 13.70 ? 351 ASP A O 1 ATOM 2781 C CB . ASP A 1 351 ? 37.725 59.791 33.179 1.00 16.00 ? 351 ASP A CB 1 ATOM 2782 C CG . ASP A 1 351 ? 39.176 59.889 33.539 1.00 20.12 ? 351 ASP A CG 1 ATOM 2783 O OD1 . ASP A 1 351 ? 39.961 58.967 33.222 1.00 23.60 ? 351 ASP A OD1 1 ATOM 2784 O OD2 . ASP A 1 351 ? 39.618 60.857 34.210 1.00 26.36 ? 351 ASP A OD2 1 ATOM 2785 N N . VAL A 1 352 ? 35.174 59.515 31.542 1.00 13.13 ? 352 VAL A N 1 ATOM 2786 C CA . VAL A 1 352 ? 33.734 59.360 31.625 1.00 13.66 ? 352 VAL A CA 1 ATOM 2787 C C . VAL A 1 352 ? 33.257 58.235 30.684 1.00 13.49 ? 352 VAL A C 1 ATOM 2788 O O . VAL A 1 352 ? 32.383 57.431 31.044 1.00 15.04 ? 352 VAL A O 1 ATOM 2789 C CB . VAL A 1 352 ? 32.995 60.715 31.444 1.00 15.28 ? 352 VAL A CB 1 ATOM 2790 C CG1 . VAL A 1 352 ? 32.795 61.086 29.986 1.00 15.61 ? 352 VAL A CG1 1 ATOM 2791 C CG2 . VAL A 1 352 ? 31.690 60.728 32.206 1.00 17.34 ? 352 VAL A CG2 1 ATOM 2792 N N . GLN A 1 353 ? 33.837 58.136 29.481 1.00 12.25 ? 353 GLN A N 1 ATOM 2793 C CA . GLN A 1 353 ? 33.443 57.063 28.575 1.00 11.45 ? 353 GLN A CA 1 ATOM 2794 C C . GLN A 1 353 ? 33.977 55.723 29.071 1.00 11.56 ? 353 GLN A C 1 ATOM 2795 O O . GLN A 1 353 ? 33.216 54.754 29.206 1.00 12.50 ? 353 GLN A O 1 ATOM 2796 C CB . GLN A 1 353 ? 33.936 57.345 27.141 1.00 11.36 ? 353 GLN A CB 1 ATOM 2797 C CG . GLN A 1 353 ? 33.400 58.637 26.498 1.00 11.85 ? 353 GLN A CG 1 ATOM 2798 C CD . GLN A 1 353 ? 31.954 58.551 26.027 1.00 10.80 ? 353 GLN A CD 1 ATOM 2799 O OE1 . GLN A 1 353 ? 31.121 57.812 26.601 1.00 12.60 ? 353 GLN A OE1 1 ATOM 2800 N NE2 . GLN A 1 353 ? 31.610 59.330 25.020 1.00 11.38 ? 353 GLN A NE2 1 ATOM 2801 N N . ARG A 1 354 ? 35.266 55.659 29.400 1.00 11.12 ? 354 ARG A N 1 ATOM 2802 C CA . ARG A 1 354 ? 35.878 54.405 29.822 1.00 11.71 ? 354 ARG A CA 1 ATOM 2803 C C . ARG A 1 354 ? 35.234 53.816 31.094 1.00 13.07 ? 354 ARG A C 1 ATOM 2804 O O . ARG A 1 354 ? 34.901 52.636 31.131 1.00 13.15 ? 354 ARG A O 1 ATOM 2805 C CB . ARG A 1 354 ? 37.379 54.544 30.023 1.00 11.44 ? 354 ARG A CB 1 ATOM 2806 C CG . ARG A 1 354 ? 38.045 53.266 30.450 1.00 11.82 ? 354 ARG A CG 1 ATOM 2807 C CD . ARG A 1 354 ? 39.536 53.420 30.768 1.00 13.97 ? 354 ARG A CD 1 ATOM 2808 N NE . ARG A 1 354 ? 39.763 54.493 31.744 1.00 16.06 ? 354 ARG A NE 1 ATOM 2809 C CZ . ARG A 1 354 ? 39.646 54.371 33.060 1.00 17.93 ? 354 ARG A CZ 1 ATOM 2810 N NH1 . ARG A 1 354 ? 39.286 53.207 33.600 1.00 17.76 ? 354 ARG A NH1 1 ATOM 2811 N NH2 . ARG A 1 354 ? 39.911 55.413 33.830 1.00 20.54 ? 354 ARG A NH2 1 ATOM 2812 N N . VAL A 1 355 ? 35.077 54.633 32.127 1.00 12.91 ? 355 VAL A N 1 ATOM 2813 C CA . VAL A 1 355 ? 34.665 54.070 33.422 1.00 14.31 ? 355 VAL A CA 1 ATOM 2814 C C . VAL A 1 355 ? 33.223 53.580 33.329 1.00 13.50 ? 355 VAL A C 1 ATOM 2815 O O . VAL A 1 355 ? 32.887 52.485 33.864 1.00 15.25 ? 355 VAL A O 1 ATOM 2816 C CB . VAL A 1 355 ? 34.824 55.091 34.568 1.00 15.01 ? 355 VAL A CB 1 ATOM 2817 C CG1 . VAL A 1 355 ? 34.343 54.516 35.879 1.00 19.57 ? 355 VAL A CG1 1 ATOM 2818 C CG2 . VAL A 1 355 ? 36.282 55.486 34.765 1.00 17.76 ? 355 VAL A CG2 1 ATOM 2819 N N . ASN A 1 356 ? 32.358 54.354 32.686 1.00 13.09 ? 356 ASN A N 1 ATOM 2820 C CA . ASN A 1 356 ? 30.969 53.942 32.499 1.00 12.59 ? 356 ASN A CA 1 ATOM 2821 C C . ASN A 1 356 ? 30.830 52.640 31.680 1.00 13.37 ? 356 ASN A C 1 ATOM 2822 O O . ASN A 1 356 ? 30.081 51.721 32.077 1.00 13.44 ? 356 ASN A O 1 ATOM 2823 C CB . ASN A 1 356 ? 30.120 55.097 32.026 1.00 13.28 ? 356 ASN A CB 1 ATOM 2824 C CG . ASN A 1 356 ? 29.871 56.095 33.129 1.00 14.06 ? 356 ASN A CG 1 ATOM 2825 O OD1 . ASN A 1 356 ? 29.152 55.775 34.093 1.00 15.43 ? 356 ASN A OD1 1 ATOM 2826 N ND2 . ASN A 1 356 ? 30.479 57.275 33.058 1.00 13.26 ? 356 ASN A ND2 1 ATOM 2827 N N . TYR A 1 357 ? 31.566 52.525 30.572 1.00 12.32 ? 357 TYR A N 1 ATOM 2828 C CA . TYR A 1 357 ? 31.545 51.292 29.795 1.00 12.19 ? 357 TYR A CA 1 ATOM 2829 C C . TYR A 1 357 ? 32.150 50.138 30.560 1.00 12.07 ? 357 TYR A C 1 ATOM 2830 O O . TYR A 1 357 ? 31.612 49.023 30.493 1.00 12.57 ? 357 TYR A O 1 ATOM 2831 C CB . TYR A 1 357 ? 32.185 51.482 28.377 1.00 11.87 ? 357 TYR A CB 1 ATOM 2832 C CG . TYR A 1 357 ? 31.178 51.998 27.402 1.00 10.74 ? 357 TYR A CG 1 ATOM 2833 C CD1 . TYR A 1 357 ? 30.310 51.118 26.722 1.00 11.40 ? 357 TYR A CD1 1 ATOM 2834 C CD2 . TYR A 1 357 ? 31.013 53.365 27.229 1.00 11.14 ? 357 TYR A CD2 1 ATOM 2835 C CE1 . TYR A 1 357 ? 29.330 51.602 25.856 1.00 11.15 ? 357 TYR A CE1 1 ATOM 2836 C CE2 . TYR A 1 357 ? 30.024 53.875 26.381 1.00 11.01 ? 357 TYR A CE2 1 ATOM 2837 C CZ . TYR A 1 357 ? 29.187 52.987 25.678 1.00 11.71 ? 357 TYR A CZ 1 ATOM 2838 O OH . TYR A 1 357 ? 28.196 53.429 24.826 1.00 12.62 ? 357 TYR A OH 1 ATOM 2839 N N . GLU A 1 358 ? 33.248 50.357 31.280 1.00 12.47 ? 358 GLU A N 1 ATOM 2840 C CA . GLU A 1 358 ? 33.779 49.262 32.111 1.00 13.39 ? 358 GLU A CA 1 ATOM 2841 C C . GLU A 1 358 ? 32.726 48.714 33.108 1.00 13.35 ? 358 GLU A C 1 ATOM 2842 O O . GLU A 1 358 ? 32.619 47.498 33.283 1.00 12.86 ? 358 GLU A O 1 ATOM 2843 C CB . GLU A 1 358 ? 35.006 49.703 32.895 1.00 13.56 ? 358 GLU A CB 1 ATOM 2844 C CG . GLU A 1 358 ? 36.294 49.848 32.082 1.00 16.03 ? 358 GLU A CG 1 ATOM 2845 C CD . GLU A 1 358 ? 37.469 50.343 32.929 1.00 17.05 ? 358 GLU A CD 1 ATOM 2846 O OE1 . GLU A 1 358 ? 37.316 50.423 34.172 1.00 25.13 ? 358 GLU A OE1 1 ATOM 2847 O OE2 . GLU A 1 358 ? 38.555 50.631 32.397 1.00 19.86 ? 358 GLU A OE2 1 ATOM 2848 N N . ARG A 1 359 ? 31.924 49.585 33.703 1.00 13.32 ? 359 ARG A N 1 ATOM 2849 C CA . ARG A 1 359 ? 30.906 49.107 34.652 1.00 14.54 ? 359 ARG A CA 1 ATOM 2850 C C . ARG A 1 359 ? 29.835 48.310 33.917 1.00 14.87 ? 359 ARG A C 1 ATOM 2851 O O . ARG A 1 359 ? 29.368 47.253 34.391 1.00 14.85 ? 359 ARG A O 1 ATOM 2852 C CB . ARG A 1 359 ? 30.264 50.263 35.391 1.00 15.58 ? 359 ARG A CB 1 ATOM 2853 C CG . ARG A 1 359 ? 31.135 50.949 36.410 1.00 17.41 ? 359 ARG A CG 1 ATOM 2854 C CD . ARG A 1 359 ? 30.454 52.201 36.868 1.00 22.47 ? 359 ARG A CD 1 ATOM 2855 N NE . ARG A 1 359 ? 31.337 53.055 37.644 1.00 26.26 ? 359 ARG A NE 1 ATOM 2856 C CZ . ARG A 1 359 ? 31.379 54.382 37.535 1.00 28.25 ? 359 ARG A CZ 1 ATOM 2857 N NH1 . ARG A 1 359 ? 30.586 55.035 36.666 1.00 24.36 ? 359 ARG A NH1 1 ATOM 2858 N NH2 . ARG A 1 359 ? 32.226 55.057 38.306 1.00 32.25 ? 359 ARG A NH2 1 ATOM 2859 N N . LEU A 1 360 ? 29.432 48.790 32.742 1.00 13.78 ? 360 LEU A N 1 ATOM 2860 C CA . LEU A 1 360 ? 28.521 48.015 31.915 1.00 13.53 ? 360 LEU A CA 1 ATOM 2861 C C . LEU A 1 360 ? 29.076 46.654 31.532 1.00 13.47 ? 360 LEU A C 1 ATOM 2862 O O . LEU A 1 360 ? 28.369 45.628 31.680 1.00 14.13 ? 360 LEU A O 1 ATOM 2863 C CB . LEU A 1 360 ? 28.114 48.823 30.685 1.00 13.39 ? 360 LEU A CB 1 ATOM 2864 C CG . LEU A 1 360 ? 27.231 50.012 31.030 1.00 13.54 ? 360 LEU A CG 1 ATOM 2865 C CD1 . LEU A 1 360 ? 27.386 51.059 29.948 1.00 15.31 ? 360 LEU A CD1 1 ATOM 2866 C CD2 . LEU A 1 360 ? 25.744 49.666 31.221 1.00 16.06 ? 360 LEU A CD2 1 ATOM 2867 N N . PHE A 1 361 ? 30.308 46.580 31.053 1.00 12.56 ? 361 PHE A N 1 ATOM 2868 C CA . PHE A 1 361 ? 30.868 45.308 30.658 1.00 13.42 ? 361 PHE A CA 1 ATOM 2869 C C . PHE A 1 361 ? 30.937 44.327 31.828 1.00 14.70 ? 361 PHE A C 1 ATOM 2870 O O . PHE A 1 361 ? 30.676 43.128 31.657 1.00 13.83 ? 361 PHE A O 1 ATOM 2871 C CB . PHE A 1 361 ? 32.286 45.470 30.111 1.00 13.13 ? 361 PHE A CB 1 ATOM 2872 C CG . PHE A 1 361 ? 32.392 46.307 28.850 1.00 11.94 ? 361 PHE A CG 1 ATOM 2873 C CD1 . PHE A 1 361 ? 31.327 46.443 27.973 1.00 11.80 ? 361 PHE A CD1 1 ATOM 2874 C CD2 . PHE A 1 361 ? 33.599 46.946 28.558 1.00 11.53 ? 361 PHE A CD2 1 ATOM 2875 C CE1 . PHE A 1 361 ? 31.466 47.223 26.785 1.00 12.26 ? 361 PHE A CE1 1 ATOM 2876 C CE2 . PHE A 1 361 ? 33.750 47.725 27.371 1.00 11.88 ? 361 PHE A CE2 1 ATOM 2877 C CZ . PHE A 1 361 ? 32.688 47.867 26.511 1.00 12.29 ? 361 PHE A CZ 1 ATOM 2878 N N . GLU A 1 362 ? 31.371 44.805 32.994 1.00 14.15 ? 362 GLU A N 1 ATOM 2879 C CA . GLU A 1 362 ? 31.504 43.902 34.142 1.00 14.47 ? 362 GLU A CA 1 ATOM 2880 C C . GLU A 1 362 ? 30.121 43.289 34.473 1.00 14.39 ? 362 GLU A C 1 ATOM 2881 O O . GLU A 1 362 ? 30.005 42.064 34.655 1.00 15.44 ? 362 GLU A O 1 ATOM 2882 C CB . GLU A 1 362 ? 32.131 44.600 35.350 1.00 16.34 ? 362 GLU A CB 1 ATOM 2883 C CG . GLU A 1 362 ? 32.291 43.575 36.479 1.00 18.73 ? 362 GLU A CG 1 ATOM 2884 C CD . GLU A 1 362 ? 32.747 44.158 37.809 1.00 25.50 ? 362 GLU A CD 1 ATOM 2885 O OE1 . GLU A 1 362 ? 33.226 45.313 37.835 1.00 28.88 ? 362 GLU A OE1 1 ATOM 2886 O OE2 . GLU A 1 362 ? 32.624 43.436 38.832 1.00 26.82 ? 362 GLU A OE2 1 ATOM 2887 N N . HIS A 1 363 ? 29.089 44.109 34.490 1.00 14.04 ? 363 HIS A N 1 ATOM 2888 C CA . HIS A 1 363 ? 27.752 43.593 34.755 1.00 15.65 ? 363 HIS A CA 1 ATOM 2889 C C . HIS A 1 363 ? 27.262 42.641 33.670 1.00 15.39 ? 363 HIS A C 1 ATOM 2890 O O . HIS A 1 363 ? 26.845 41.523 33.948 1.00 16.30 ? 363 HIS A O 1 ATOM 2891 C CB . HIS A 1 363 ? 26.766 44.718 34.976 1.00 15.97 ? 363 HIS A CB 1 ATOM 2892 C CG . HIS A 1 363 ? 25.372 44.238 35.276 1.00 17.19 ? 363 HIS A CG 1 ATOM 2893 N ND1 . HIS A 1 363 ? 25.002 43.742 36.517 1.00 22.83 ? 363 HIS A ND1 1 ATOM 2894 C CD2 . HIS A 1 363 ? 24.266 44.178 34.500 1.00 19.33 ? 363 HIS A CD2 1 ATOM 2895 C CE1 . HIS A 1 363 ? 23.729 43.381 36.471 1.00 21.07 ? 363 HIS A CE1 1 ATOM 2896 N NE2 . HIS A 1 363 ? 23.255 43.644 35.266 1.00 23.21 ? 363 HIS A NE2 1 ATOM 2897 N N . ILE A 1 364 ? 27.308 43.090 32.418 1.00 15.12 ? 364 ILE A N 1 ATOM 2898 C CA . ILE A 1 364 ? 26.749 42.320 31.324 1.00 14.30 ? 364 ILE A CA 1 ATOM 2899 C C . ILE A 1 364 ? 27.457 40.992 31.215 1.00 14.43 ? 364 ILE A C 1 ATOM 2900 O O . ILE A 1 364 ? 26.800 39.934 31.041 1.00 14.96 ? 364 ILE A O 1 ATOM 2901 C CB . ILE A 1 364 ? 26.855 43.134 29.987 1.00 14.54 ? 364 ILE A CB 1 ATOM 2902 C CG1 . ILE A 1 364 ? 25.871 44.296 30.048 1.00 14.95 ? 364 ILE A CG1 1 ATOM 2903 C CG2 . ILE A 1 364 ? 26.637 42.205 28.788 1.00 13.95 ? 364 ILE A CG2 1 ATOM 2904 C CD1 . ILE A 1 364 ? 26.133 45.409 29.032 1.00 14.62 ? 364 ILE A CD1 1 ATOM 2905 N N . ASN A 1 365 ? 28.768 40.997 31.311 1.00 14.02 ? 365 ASN A N 1 ATOM 2906 C CA . ASN A 1 365 ? 29.551 39.793 31.054 1.00 14.80 ? 365 ASN A CA 1 ATOM 2907 C C . ASN A 1 365 ? 29.389 38.754 32.169 1.00 16.83 ? 365 ASN A C 1 ATOM 2908 O O . ASN A 1 365 ? 29.685 37.582 31.973 1.00 16.52 ? 365 ASN A O 1 ATOM 2909 C CB . ASN A 1 365 ? 31.028 40.116 30.850 1.00 14.19 ? 365 ASN A CB 1 ATOM 2910 C CG . ASN A 1 365 ? 31.277 40.931 29.580 1.00 13.27 ? 365 ASN A CG 1 ATOM 2911 O OD1 . ASN A 1 365 ? 30.358 41.095 28.760 1.00 13.70 ? 365 ASN A OD1 1 ATOM 2912 N ND2 . ASN A 1 365 ? 32.518 41.426 29.423 1.00 12.67 ? 365 ASN A ND2 1 ATOM 2913 N N . SER A 1 366 ? 28.933 39.223 33.332 1.00 18.56 ? 366 SER A N 1 ATOM 2914 C CA . SER A 1 366 ? 28.785 38.374 34.535 1.00 21.58 ? 366 SER A CA 1 ATOM 2915 C C . SER A 1 366 ? 27.376 37.827 34.671 1.00 22.62 ? 366 SER A C 1 ATOM 2916 O O . SER A 1 366 ? 27.137 36.938 35.504 1.00 23.52 ? 366 SER A O 1 ATOM 2917 C CB . SER A 1 366 ? 29.152 39.166 35.801 1.00 21.91 ? 366 SER A CB 1 ATOM 2918 O OG . SER A 1 366 ? 28.107 40.070 36.096 1.00 25.08 ? 366 SER A OG 1 ATOM 2919 N N . GLN A 1 367 ? 26.435 38.372 33.911 1.00 22.92 ? 367 GLN A N 1 ATOM 2920 C CA . GLN A 1 367 ? 25.034 37.986 33.979 1.00 24.33 ? 367 GLN A CA 1 ATOM 2921 C C . GLN A 1 367 ? 24.719 37.029 32.848 1.00 24.15 ? 367 GLN A C 1 ATOM 2922 O O . GLN A 1 367 ? 24.388 37.447 31.725 1.00 23.52 ? 367 GLN A O 1 ATOM 2923 C CB . GLN A 1 367 ? 24.118 39.206 33.901 1.00 25.05 ? 367 GLN A CB 1 ATOM 2924 C CG . GLN A 1 367 ? 24.186 40.115 35.115 1.00 28.85 ? 367 GLN A CG 1 ATOM 2925 C CD . GLN A 1 367 ? 23.411 39.566 36.292 1.00 32.99 ? 367 GLN A CD 1 ATOM 2926 O OE1 . GLN A 1 367 ? 22.200 39.344 36.200 1.00 34.41 ? 367 GLN A OE1 1 ATOM 2927 N NE2 . GLN A 1 367 ? 24.104 39.358 37.408 1.00 35.15 ? 367 GLN A NE2 1 ATOM 2928 N N . ALA A 1 368 ? 24.781 35.734 33.163 1.00 24.03 ? 368 ALA A N 1 ATOM 2929 C CA . ALA A 1 368 ? 24.578 34.685 32.161 1.00 23.11 ? 368 ALA A CA 1 ATOM 2930 C C . ALA A 1 368 ? 23.352 34.883 31.277 1.00 22.75 ? 368 ALA A C 1 ATOM 2931 O O . ALA A 1 368 ? 23.414 34.593 30.074 1.00 22.20 ? 368 ALA A O 1 ATOM 2932 C CB . ALA A 1 368 ? 24.518 33.321 32.842 1.00 23.70 ? 368 ALA A CB 1 ATOM 2933 N N . HIS A 1 369 ? 22.249 35.370 31.849 1.00 21.39 ? 369 HIS A N 1 ATOM 2934 C CA . HIS A 1 369 ? 20.992 35.528 31.124 1.00 21.89 ? 369 HIS A CA 1 ATOM 2935 C C . HIS A 1 369 ? 21.107 36.423 29.872 1.00 20.72 ? 369 HIS A C 1 ATOM 2936 O O . HIS A 1 369 ? 20.290 36.319 28.954 1.00 21.61 ? 369 HIS A O 1 ATOM 2937 C CB . HIS A 1 369 ? 19.883 36.054 32.051 1.00 22.81 ? 369 HIS A CB 1 ATOM 2938 C CG . HIS A 1 369 ? 20.098 37.460 32.518 1.00 24.67 ? 369 HIS A CG 1 ATOM 2939 N ND1 . HIS A 1 369 ? 19.613 38.551 31.828 1.00 28.45 ? 369 HIS A ND1 1 ATOM 2940 C CD2 . HIS A 1 369 ? 20.737 37.955 33.602 1.00 27.79 ? 369 HIS A CD2 1 ATOM 2941 C CE1 . HIS A 1 369 ? 19.947 39.658 32.463 1.00 26.70 ? 369 HIS A CE1 1 ATOM 2942 N NE2 . HIS A 1 369 ? 20.636 39.325 33.541 1.00 28.40 ? 369 HIS A NE2 1 ATOM 2943 N N . PHE A 1 370 ? 22.101 37.315 29.850 1.00 20.73 ? 370 PHE A N 1 ATOM 2944 C CA . PHE A 1 370 ? 22.304 38.148 28.656 1.00 18.61 ? 370 PHE A CA 1 ATOM 2945 C C . PHE A 1 370 ? 22.926 37.356 27.503 1.00 17.15 ? 370 PHE A C 1 ATOM 2946 O O . PHE A 1 370 ? 22.681 37.673 26.339 1.00 16.36 ? 370 PHE A O 1 ATOM 2947 C CB . PHE A 1 370 ? 23.248 39.322 28.934 1.00 19.41 ? 370 PHE A CB 1 ATOM 2948 C CG . PHE A 1 370 ? 22.681 40.415 29.800 1.00 20.00 ? 370 PHE A CG 1 ATOM 2949 C CD1 . PHE A 1 370 ? 21.536 41.112 29.427 1.00 20.69 ? 370 PHE A CD1 1 ATOM 2950 C CD2 . PHE A 1 370 ? 23.363 40.794 30.940 1.00 21.34 ? 370 PHE A CD2 1 ATOM 2951 C CE1 . PHE A 1 370 ? 21.048 42.171 30.234 1.00 22.79 ? 370 PHE A CE1 1 ATOM 2952 C CE2 . PHE A 1 370 ? 22.897 41.824 31.742 1.00 23.07 ? 370 PHE A CE2 1 ATOM 2953 C CZ . PHE A 1 370 ? 21.746 42.518 31.380 1.00 21.01 ? 370 PHE A CZ 1 ATOM 2954 N N . ASN A 1 371 ? 23.765 36.379 27.839 1.00 15.09 ? 371 ASN A N 1 ATOM 2955 C CA . ASN A 1 371 ? 24.541 35.619 26.879 1.00 14.81 ? 371 ASN A CA 1 ATOM 2956 C C . ASN A 1 371 ? 25.336 36.531 25.944 1.00 13.47 ? 371 ASN A C 1 ATOM 2957 O O . ASN A 1 371 ? 25.321 36.365 24.728 1.00 13.89 ? 371 ASN A O 1 ATOM 2958 C CB . ASN A 1 371 ? 23.654 34.635 26.097 1.00 15.42 ? 371 ASN A CB 1 ATOM 2959 C CG . ASN A 1 371 ? 22.981 33.604 27.015 1.00 16.40 ? 371 ASN A CG 1 ATOM 2960 O OD1 . ASN A 1 371 ? 23.660 32.803 27.644 1.00 18.85 ? 371 ASN A OD1 1 ATOM 2961 N ND2 . ASN A 1 371 ? 21.667 33.677 27.113 1.00 19.26 ? 371 ASN A ND2 1 ATOM 2962 N N . VAL A 1 372 ? 26.019 37.486 26.550 1.00 12.76 ? 372 VAL A N 1 ATOM 2963 C CA . VAL A 1 372 ? 26.829 38.472 25.817 1.00 13.06 ? 372 VAL A CA 1 ATOM 2964 C C . VAL A 1 372 ? 28.216 38.497 26.424 1.00 13.42 ? 372 VAL A C 1 ATOM 2965 O O . VAL A 1 372 ? 28.375 38.424 27.664 1.00 14.02 ? 372 VAL A O 1 ATOM 2966 C CB . VAL A 1 372 ? 26.184 39.883 25.906 1.00 13.18 ? 372 VAL A CB 1 ATOM 2967 C CG1 . VAL A 1 372 ? 27.169 40.987 25.390 1.00 13.38 ? 372 VAL A CG1 1 ATOM 2968 C CG2 . VAL A 1 372 ? 24.884 39.947 25.132 1.00 13.99 ? 372 VAL A CG2 1 ATOM 2969 N N . GLN A 1 373 ? 29.244 38.625 25.584 1.00 12.60 ? 373 GLN A N 1 ATOM 2970 C CA . GLN A 1 373 ? 30.600 38.952 26.036 1.00 12.13 ? 373 GLN A CA 1 ATOM 2971 C C . GLN A 1 373 ? 30.981 40.262 25.319 1.00 11.68 ? 373 GLN A C 1 ATOM 2972 O O . GLN A 1 373 ? 31.173 40.244 24.091 1.00 11.84 ? 373 GLN A O 1 ATOM 2973 C CB . GLN A 1 373 ? 31.592 37.820 25.713 1.00 13.23 ? 373 GLN A CB 1 ATOM 2974 C CG . GLN A 1 373 ? 33.073 38.137 26.036 1.00 15.26 ? 373 GLN A CG 1 ATOM 2975 C CD . GLN A 1 373 ? 33.303 38.473 27.518 1.00 19.16 ? 373 GLN A CD 1 ATOM 2976 O OE1 . GLN A 1 373 ? 32.594 37.958 28.409 1.00 19.45 ? 373 GLN A OE1 1 ATOM 2977 N NE2 . GLN A 1 373 ? 34.293 39.324 27.785 1.00 19.83 ? 373 GLN A NE2 1 ATOM 2978 N N . ALA A 1 374 ? 31.072 41.379 26.043 1.00 10.75 ? 374 ALA A N 1 ATOM 2979 C CA . ALA A 1 374 ? 31.342 42.701 25.455 1.00 11.40 ? 374 ALA A CA 1 ATOM 2980 C C . ALA A 1 374 ? 32.675 43.233 25.934 1.00 11.41 ? 374 ALA A C 1 ATOM 2981 O O . ALA A 1 374 ? 33.036 43.055 27.127 1.00 11.49 ? 374 ALA A O 1 ATOM 2982 C CB . ALA A 1 374 ? 30.245 43.647 25.840 1.00 11.03 ? 374 ALA A CB 1 ATOM 2983 N N . GLN A 1 375 ? 33.399 43.925 25.055 1.00 10.95 ? 375 GLN A N 1 ATOM 2984 C CA A GLN A 1 375 ? 34.709 44.470 25.408 0.50 11.10 ? 375 GLN A CA 1 ATOM 2985 C CA B GLN A 1 375 ? 34.712 44.464 25.407 0.50 11.42 ? 375 GLN A CA 1 ATOM 2986 C C . GLN A 1 375 ? 35.070 45.594 24.466 1.00 10.80 ? 375 GLN A C 1 ATOM 2987 O O . GLN A 1 375 ? 34.511 45.683 23.367 1.00 11.06 ? 375 GLN A O 1 ATOM 2988 C CB A GLN A 1 375 ? 35.781 43.399 25.291 0.50 11.38 ? 375 GLN A CB 1 ATOM 2989 C CB B GLN A 1 375 ? 35.777 43.376 25.309 0.50 12.03 ? 375 GLN A CB 1 ATOM 2990 C CG A GLN A 1 375 ? 35.717 42.600 23.993 0.50 12.94 ? 375 GLN A CG 1 ATOM 2991 C CG B GLN A 1 375 ? 35.895 42.724 23.929 0.50 14.82 ? 375 GLN A CG 1 ATOM 2992 C CD A GLN A 1 375 ? 34.885 41.324 24.123 0.50 13.06 ? 375 GLN A CD 1 ATOM 2993 C CD B GLN A 1 375 ? 36.390 41.282 23.987 0.50 18.51 ? 375 GLN A CD 1 ATOM 2994 O OE1 A GLN A 1 375 ? 35.118 40.505 25.025 0.50 14.76 ? 375 GLN A OE1 1 ATOM 2995 O OE1 B GLN A 1 375 ? 35.803 40.439 24.669 0.50 20.88 ? 375 GLN A OE1 1 ATOM 2996 N NE2 A GLN A 1 375 ? 33.900 41.158 23.239 0.50 12.20 ? 375 GLN A NE2 1 ATOM 2997 N NE2 B GLN A 1 375 ? 37.473 41.001 23.283 0.50 19.17 ? 375 GLN A NE2 1 ATOM 2998 N N . PHE A 1 376 ? 35.993 46.444 24.904 1.00 10.20 ? 376 PHE A N 1 ATOM 2999 C CA . PHE A 1 376 ? 36.608 47.354 23.937 1.00 10.73 ? 376 PHE A CA 1 ATOM 3000 C C . PHE A 1 376 ? 37.398 46.533 22.962 1.00 11.25 ? 376 PHE A C 1 ATOM 3001 O O . PHE A 1 376 ? 38.037 45.551 23.314 1.00 12.01 ? 376 PHE A O 1 ATOM 3002 C CB . PHE A 1 376 ? 37.554 48.320 24.624 1.00 11.43 ? 376 PHE A CB 1 ATOM 3003 C CG . PHE A 1 376 ? 36.883 49.248 25.558 1.00 10.43 ? 376 PHE A CG 1 ATOM 3004 C CD1 . PHE A 1 376 ? 35.877 50.096 25.119 1.00 11.68 ? 376 PHE A CD1 1 ATOM 3005 C CD2 . PHE A 1 376 ? 37.277 49.301 26.910 1.00 12.03 ? 376 PHE A CD2 1 ATOM 3006 C CE1 . PHE A 1 376 ? 35.250 50.990 26.029 1.00 13.84 ? 376 PHE A CE1 1 ATOM 3007 C CE2 . PHE A 1 376 ? 36.618 50.177 27.803 1.00 13.67 ? 376 PHE A CE2 1 ATOM 3008 C CZ . PHE A 1 376 ? 35.640 51.007 27.353 1.00 13.80 ? 376 PHE A CZ 1 ATOM 3009 N N . GLY A 1 377 ? 37.364 46.959 21.701 1.00 10.27 ? 377 GLY A N 1 ATOM 3010 C CA . GLY A 1 377 ? 38.083 46.263 20.659 1.00 10.88 ? 377 GLY A CA 1 ATOM 3011 C C . GLY A 1 377 ? 38.564 47.250 19.610 1.00 9.34 ? 377 GLY A C 1 ATOM 3012 O O . GLY A 1 377 ? 38.262 48.421 19.638 1.00 10.20 ? 377 GLY A O 1 ATOM 3013 N N . THR A 1 378 ? 39.307 46.688 18.664 1.00 10.92 ? 378 THR A N 1 ATOM 3014 C CA . THR A 1 378 ? 39.709 47.411 17.466 1.00 11.13 ? 378 THR A CA 1 ATOM 3015 C C . THR A 1 378 ? 38.948 46.874 16.265 1.00 10.66 ? 378 THR A C 1 ATOM 3016 O O . THR A 1 378 ? 38.240 45.840 16.303 1.00 10.67 ? 378 THR A O 1 ATOM 3017 C CB . THR A 1 378 ? 41.218 47.319 17.202 1.00 11.54 ? 378 THR A CB 1 ATOM 3018 O OG1 . THR A 1 378 ? 41.546 45.976 16.851 1.00 12.86 ? 378 THR A OG1 1 ATOM 3019 C CG2 . THR A 1 378 ? 42.062 47.668 18.460 1.00 13.74 ? 378 THR A CG2 1 ATOM 3020 N N . LEU A 1 379 ? 39.115 47.592 15.159 1.00 9.93 ? 379 LEU A N 1 ATOM 3021 C CA . LEU A 1 379 ? 38.465 47.183 13.927 1.00 9.74 ? 379 LEU A CA 1 ATOM 3022 C C . LEU A 1 379 ? 38.956 45.817 13.433 1.00 9.34 ? 379 LEU A C 1 ATOM 3023 O O . LEU A 1 379 ? 38.169 44.951 13.038 1.00 9.09 ? 379 LEU A O 1 ATOM 3024 C CB . LEU A 1 379 ? 38.650 48.275 12.872 1.00 9.61 ? 379 LEU A CB 1 ATOM 3025 C CG . LEU A 1 379 ? 37.873 48.027 11.578 1.00 10.03 ? 379 LEU A CG 1 ATOM 3026 C CD1 . LEU A 1 379 ? 36.355 48.061 11.819 1.00 11.13 ? 379 LEU A CD1 1 ATOM 3027 C CD2 . LEU A 1 379 ? 38.286 49.101 10.527 1.00 10.53 ? 379 LEU A CD2 1 ATOM 3028 N N . GLN A 1 380 ? 40.270 45.617 13.430 1.00 9.08 ? 380 GLN A N 1 ATOM 3029 C CA . GLN A 1 380 ? 40.815 44.334 13.004 1.00 10.28 ? 380 GLN A CA 1 ATOM 3030 C C . GLN A 1 380 ? 40.307 43.187 13.883 1.00 10.29 ? 380 GLN A C 1 ATOM 3031 O O . GLN A 1 380 ? 40.057 42.079 13.380 1.00 10.32 ? 380 GLN A O 1 ATOM 3032 C CB . GLN A 1 380 ? 42.346 44.374 12.971 1.00 11.37 ? 380 GLN A CB 1 ATOM 3033 C CG . GLN A 1 380 ? 42.978 43.079 12.427 1.00 13.33 ? 380 GLN A CG 1 ATOM 3034 C CD . GLN A 1 380 ? 42.703 42.923 10.962 1.00 14.86 ? 380 GLN A CD 1 ATOM 3035 O OE1 . GLN A 1 380 ? 42.794 43.896 10.208 1.00 15.69 ? 380 GLN A OE1 1 ATOM 3036 N NE2 . GLN A 1 380 ? 42.337 41.704 10.543 1.00 18.87 ? 380 GLN A NE2 1 ATOM 3037 N N . GLU A 1 381 ? 40.168 43.424 15.181 1.00 10.47 ? 381 GLU A N 1 ATOM 3038 C CA . GLU A 1 381 ? 39.674 42.359 16.064 1.00 11.05 ? 381 GLU A CA 1 ATOM 3039 C C . GLU A 1 381 ? 38.244 41.975 15.673 1.00 10.42 ? 381 GLU A C 1 ATOM 3040 O O . GLU A 1 381 ? 37.914 40.789 15.654 1.00 11.95 ? 381 GLU A O 1 ATOM 3041 C CB . GLU A 1 381 ? 39.657 42.841 17.512 1.00 12.04 ? 381 GLU A CB 1 ATOM 3042 C CG . GLU A 1 381 ? 40.973 42.860 18.278 1.00 16.36 ? 381 GLU A CG 1 ATOM 3043 C CD . GLU A 1 381 ? 40.662 43.185 19.728 1.00 22.27 ? 381 GLU A CD 1 ATOM 3044 O OE1 . GLU A 1 381 ? 40.485 44.352 20.008 1.00 20.97 ? 381 GLU A OE1 1 ATOM 3045 O OE2 . GLU A 1 381 ? 40.534 42.262 20.595 1.00 27.81 ? 381 GLU A OE2 1 ATOM 3046 N N . TYR A 1 382 ? 37.411 42.964 15.360 1.00 9.78 ? 382 TYR A N 1 ATOM 3047 C CA . TYR A 1 382 ? 36.076 42.666 14.862 1.00 9.12 ? 382 TYR A CA 1 ATOM 3048 C C . TYR A 1 382 ? 36.120 41.773 13.613 1.00 8.98 ? 382 TYR A C 1 ATOM 3049 O O . TYR A 1 382 ? 35.479 40.723 13.541 1.00 9.35 ? 382 TYR A O 1 ATOM 3050 C CB . TYR A 1 382 ? 35.303 43.961 14.550 1.00 9.68 ? 382 TYR A CB 1 ATOM 3051 C CG . TYR A 1 382 ? 33.999 43.671 13.842 1.00 8.75 ? 382 TYR A CG 1 ATOM 3052 C CD1 . TYR A 1 382 ? 32.926 43.089 14.527 1.00 9.18 ? 382 TYR A CD1 1 ATOM 3053 C CD2 . TYR A 1 382 ? 33.857 43.889 12.455 1.00 9.56 ? 382 TYR A CD2 1 ATOM 3054 C CE1 . TYR A 1 382 ? 31.742 42.750 13.864 1.00 10.65 ? 382 TYR A CE1 1 ATOM 3055 C CE2 . TYR A 1 382 ? 32.671 43.590 11.798 1.00 10.58 ? 382 TYR A CE2 1 ATOM 3056 C CZ . TYR A 1 382 ? 31.621 42.996 12.523 1.00 9.98 ? 382 TYR A CZ 1 ATOM 3057 O OH . TYR A 1 382 ? 30.414 42.654 11.914 1.00 10.54 ? 382 TYR A OH 1 ATOM 3058 N N . PHE A 1 383 ? 36.869 42.203 12.601 1.00 8.79 ? 383 PHE A N 1 ATOM 3059 C CA . PHE A 1 383 ? 36.901 41.428 11.366 1.00 8.63 ? 383 PHE A CA 1 ATOM 3060 C C . PHE A 1 383 ? 37.480 40.026 11.586 1.00 9.11 ? 383 PHE A C 1 ATOM 3061 O O . PHE A 1 383 ? 36.994 39.060 11.001 1.00 10.27 ? 383 PHE A O 1 ATOM 3062 C CB . PHE A 1 383 ? 37.668 42.163 10.265 1.00 8.81 ? 383 PHE A CB 1 ATOM 3063 C CG . PHE A 1 383 ? 36.910 43.333 9.655 1.00 9.11 ? 383 PHE A CG 1 ATOM 3064 C CD1 . PHE A 1 383 ? 35.697 43.130 8.996 1.00 10.03 ? 383 PHE A CD1 1 ATOM 3065 C CD2 . PHE A 1 383 ? 37.439 44.633 9.695 1.00 9.42 ? 383 PHE A CD2 1 ATOM 3066 C CE1 . PHE A 1 383 ? 34.997 44.183 8.419 1.00 10.48 ? 383 PHE A CE1 1 ATOM 3067 C CE2 . PHE A 1 383 ? 36.742 45.694 9.090 1.00 9.24 ? 383 PHE A CE2 1 ATOM 3068 C CZ . PHE A 1 383 ? 35.534 45.468 8.467 1.00 9.11 ? 383 PHE A CZ 1 ATOM 3069 N N . ASP A 1 384 ? 38.533 39.926 12.399 1.00 10.38 ? 384 ASP A N 1 ATOM 3070 C CA . ASP A 1 384 ? 39.106 38.587 12.665 1.00 12.05 ? 384 ASP A CA 1 ATOM 3071 C C . ASP A 1 384 ? 38.053 37.656 13.260 1.00 11.20 ? 384 ASP A C 1 ATOM 3072 O O . ASP A 1 384 ? 37.942 36.468 12.867 1.00 12.06 ? 384 ASP A O 1 ATOM 3073 C CB . ASP A 1 384 ? 40.253 38.700 13.659 1.00 12.52 ? 384 ASP A CB 1 ATOM 3074 C CG . ASP A 1 384 ? 41.479 39.297 13.073 1.00 15.19 ? 384 ASP A CG 1 ATOM 3075 O OD1 . ASP A 1 384 ? 41.608 39.449 11.838 1.00 17.45 ? 384 ASP A OD1 1 ATOM 3076 O OD2 . ASP A 1 384 ? 42.390 39.647 13.845 1.00 18.05 ? 384 ASP A OD2 1 ATOM 3077 N N . ALA A 1 385 ? 37.268 38.176 14.190 1.00 10.55 ? 385 ALA A N 1 ATOM 3078 C CA . ALA A 1 385 ? 36.233 37.370 14.824 1.00 11.36 ? 385 ALA A CA 1 ATOM 3079 C C . ALA A 1 385 ? 35.110 37.028 13.849 1.00 11.96 ? 385 ALA A C 1 ATOM 3080 O O . ALA A 1 385 ? 34.622 35.899 13.841 1.00 12.24 ? 385 ALA A O 1 ATOM 3081 C CB . ALA A 1 385 ? 35.708 38.082 16.061 1.00 11.54 ? 385 ALA A CB 1 ATOM 3082 N N . VAL A 1 386 ? 34.715 37.969 12.974 1.00 11.11 ? 386 VAL A N 1 ATOM 3083 C CA . VAL A 1 386 ? 33.720 37.643 11.951 1.00 11.70 ? 386 VAL A CA 1 ATOM 3084 C C . VAL A 1 386 ? 34.183 36.502 11.063 1.00 11.87 ? 386 VAL A C 1 ATOM 3085 O O . VAL A 1 386 ? 33.417 35.569 10.761 1.00 11.98 ? 386 VAL A O 1 ATOM 3086 C CB . VAL A 1 386 ? 33.384 38.891 11.063 1.00 11.09 ? 386 VAL A CB 1 ATOM 3087 C CG1 . VAL A 1 386 ? 32.583 38.507 9.817 1.00 13.41 ? 386 VAL A CG1 1 ATOM 3088 C CG2 . VAL A 1 386 ? 32.634 39.900 11.893 1.00 12.59 ? 386 VAL A CG2 1 ATOM 3089 N N . HIS A 1 387 ? 35.435 36.568 10.635 1.00 11.53 ? 387 HIS A N 1 ATOM 3090 C CA . HIS A 1 387 ? 35.944 35.529 9.725 1.00 12.40 ? 387 HIS A CA 1 ATOM 3091 C C . HIS A 1 387 ? 36.161 34.184 10.421 1.00 12.75 ? 387 HIS A C 1 ATOM 3092 O O . HIS A 1 387 ? 36.029 33.127 9.779 1.00 13.50 ? 387 HIS A O 1 ATOM 3093 C CB . HIS A 1 387 ? 37.173 35.994 8.953 1.00 13.19 ? 387 HIS A CB 1 ATOM 3094 C CG . HIS A 1 387 ? 36.866 37.122 8.022 1.00 11.72 ? 387 HIS A CG 1 ATOM 3095 N ND1 . HIS A 1 387 ? 35.922 37.011 7.026 1.00 15.88 ? 387 HIS A ND1 1 ATOM 3096 C CD2 . HIS A 1 387 ? 37.328 38.394 7.966 1.00 12.68 ? 387 HIS A CD2 1 ATOM 3097 C CE1 . HIS A 1 387 ? 35.838 38.159 6.372 1.00 16.69 ? 387 HIS A CE1 1 ATOM 3098 N NE2 . HIS A 1 387 ? 36.681 39.011 6.926 1.00 14.44 ? 387 HIS A NE2 1 ATOM 3099 N N . GLN A 1 388 ? 36.424 34.225 11.718 1.00 13.73 ? 388 GLN A N 1 ATOM 3100 C CA . GLN A 1 388 ? 36.485 32.981 12.511 1.00 15.33 ? 388 GLN A CA 1 ATOM 3101 C C . GLN A 1 388 ? 35.114 32.320 12.511 1.00 16.40 ? 388 GLN A C 1 ATOM 3102 O O . GLN A 1 388 ? 35.007 31.097 12.299 1.00 16.57 ? 388 GLN A O 1 ATOM 3103 C CB . GLN A 1 388 ? 36.996 33.290 13.904 1.00 15.62 ? 388 GLN A CB 1 ATOM 3104 C CG . GLN A 1 388 ? 38.508 33.516 13.945 1.00 19.94 ? 388 GLN A CG 1 ATOM 3105 C CD . GLN A 1 388 ? 38.972 34.254 15.200 1.00 27.00 ? 388 GLN A CD 1 ATOM 3106 O OE1 . GLN A 1 388 ? 38.177 34.509 16.119 1.00 30.72 ? 388 GLN A OE1 1 ATOM 3107 N NE2 . GLN A 1 388 ? 40.259 34.611 15.239 1.00 29.80 ? 388 GLN A NE2 1 ATOM 3108 N N . ALA A 1 389 ? 34.064 33.117 12.667 1.00 16.62 ? 389 ALA A N 1 ATOM 3109 C CA . ALA A 1 389 ? 32.673 32.637 12.629 1.00 18.15 ? 389 ALA A CA 1 ATOM 3110 C C . ALA A 1 389 ? 32.313 32.059 11.267 1.00 19.34 ? 389 ALA A C 1 ATOM 3111 O O . ALA A 1 389 ? 31.664 31.009 11.193 1.00 20.63 ? 389 ALA A O 1 ATOM 3112 C CB . ALA A 1 389 ? 31.727 33.771 12.997 1.00 17.33 ? 389 ALA A CB 1 ATOM 3113 N N . GLU A 1 390 ? 32.738 32.743 10.199 1.00 19.52 ? 390 GLU A N 1 ATOM 3114 C CA . GLU A 1 390 ? 32.556 32.312 8.815 1.00 21.29 ? 390 GLU A CA 1 ATOM 3115 C C . GLU A 1 390 ? 33.221 30.968 8.566 1.00 22.07 ? 390 GLU A C 1 ATOM 3116 O O . GLU A 1 390 ? 32.601 30.067 7.986 1.00 22.81 ? 390 GLU A O 1 ATOM 3117 C CB . GLU A 1 390 ? 33.136 33.373 7.862 1.00 20.60 ? 390 GLU A CB 1 ATOM 3118 C CG . GLU A 1 390 ? 32.985 33.087 6.369 1.00 22.00 ? 390 GLU A CG 1 ATOM 3119 C CD . GLU A 1 390 ? 33.751 34.082 5.512 1.00 23.63 ? 390 GLU A CD 1 ATOM 3120 O OE1 . GLU A 1 390 ? 34.575 34.847 6.070 1.00 23.94 ? 390 GLU A OE1 1 ATOM 3121 O OE2 . GLU A 1 390 ? 33.536 34.103 4.272 1.00 27.90 ? 390 GLU A OE2 1 ATOM 3122 N N . ARG A 1 391 ? 34.471 30.826 9.009 1.00 22.79 ? 391 ARG A N 1 ATOM 3123 C CA . ARG A 1 391 ? 35.199 29.564 8.848 1.00 24.65 ? 391 ARG A CA 1 ATOM 3124 C C . ARG A 1 391 ? 34.559 28.435 9.672 1.00 24.13 ? 391 ARG A C 1 ATOM 3125 O O . ARG A 1 391 ? 34.629 27.257 9.279 1.00 25.82 ? 391 ARG A O 1 ATOM 3126 C CB . ARG A 1 391 ? 36.667 29.725 9.228 1.00 24.37 ? 391 ARG A CB 1 ATOM 3127 C CG . ARG A 1 391 ? 37.463 30.591 8.278 1.00 26.82 ? 391 ARG A CG 1 ATOM 3128 C CD . ARG A 1 391 ? 38.973 30.497 8.452 1.00 26.94 ? 391 ARG A CD 1 ATOM 3129 N NE . ARG A 1 391 ? 39.450 30.924 9.767 1.00 31.65 ? 391 ARG A NE 1 ATOM 3130 C CZ . ARG A 1 391 ? 39.664 32.192 10.131 1.00 32.65 ? 391 ARG A CZ 1 ATOM 3131 N NH1 . ARG A 1 391 ? 39.420 33.195 9.297 1.00 33.05 ? 391 ARG A NH1 1 ATOM 3132 N NH2 . ARG A 1 391 ? 40.108 32.456 11.350 1.00 34.09 ? 391 ARG A NH2 1 ATOM 3133 N N . ALA A 1 392 ? 33.929 28.781 10.791 1.00 24.24 ? 392 ALA A N 1 ATOM 3134 C CA . ALA A 1 392 ? 33.216 27.793 11.610 1.00 24.80 ? 392 ALA A CA 1 ATOM 3135 C C . ALA A 1 392 ? 31.896 27.363 10.949 1.00 25.30 ? 392 ALA A C 1 ATOM 3136 O O . ALA A 1 392 ? 31.139 26.552 11.521 1.00 26.48 ? 392 ALA A O 1 ATOM 3137 C CB . ALA A 1 392 ? 32.967 28.330 13.000 1.00 24.78 ? 392 ALA A CB 1 ATOM 3138 N N . GLY A 1 393 ? 31.634 27.888 9.748 1.00 24.95 ? 393 GLY A N 1 ATOM 3139 C CA . GLY A 1 393 ? 30.424 27.582 9.005 1.00 24.89 ? 393 GLY A CA 1 ATOM 3140 C C . GLY A 1 393 ? 29.194 28.268 9.540 1.00 24.30 ? 393 GLY A C 1 ATOM 3141 O O . GLY A 1 393 ? 28.077 27.851 9.246 1.00 24.97 ? 393 GLY A O 1 ATOM 3142 N N . GLN A 1 394 ? 29.366 29.344 10.304 1.00 24.08 ? 394 GLN A N 1 ATOM 3143 C CA . GLN A 1 394 ? 28.200 29.957 10.916 1.00 24.57 ? 394 GLN A CA 1 ATOM 3144 C C . GLN A 1 394 ? 27.520 30.991 10.000 1.00 23.64 ? 394 GLN A C 1 ATOM 3145 O O . GLN A 1 394 ? 26.368 31.379 10.237 1.00 24.68 ? 394 GLN A O 1 ATOM 3146 C CB . GLN A 1 394 ? 28.517 30.474 12.325 1.00 25.67 ? 394 GLN A CB 1 ATOM 3147 C CG . GLN A 1 394 ? 28.777 31.934 12.427 1.00 28.77 ? 394 GLN A CG 1 ATOM 3148 C CD . GLN A 1 394 ? 28.617 32.441 13.852 1.00 29.34 ? 394 GLN A CD 1 ATOM 3149 O OE1 . GLN A 1 394 ? 28.005 33.469 14.052 1.00 25.98 ? 394 GLN A OE1 1 ATOM 3150 N NE2 . GLN A 1 394 ? 29.165 31.713 14.838 1.00 29.52 ? 394 GLN A NE2 1 ATOM 3151 N N . ALA A 1 395 ? 28.213 31.381 8.923 1.00 22.32 ? 395 ALA A N 1 ATOM 3152 C CA . ALA A 1 395 ? 27.684 32.365 7.977 1.00 21.34 ? 395 ALA A CA 1 ATOM 3153 C C . ALA A 1 395 ? 28.312 32.220 6.587 1.00 20.98 ? 395 ALA A C 1 ATOM 3154 O O . ALA A 1 395 ? 29.470 31.824 6.456 1.00 20.75 ? 395 ALA A O 1 ATOM 3155 C CB . ALA A 1 395 ? 27.909 33.802 8.533 1.00 21.90 ? 395 ALA A CB 1 ATOM 3156 N N . GLU A 1 396 ? 27.532 32.521 5.554 1.00 20.61 ? 396 GLU A N 1 ATOM 3157 C CA . GLU A 1 396 ? 28.066 32.718 4.210 1.00 21.18 ? 396 GLU A CA 1 ATOM 3158 C C . GLU A 1 396 ? 27.684 34.140 3.814 1.00 18.47 ? 396 GLU A C 1 ATOM 3159 O O . GLU A 1 396 ? 26.610 34.624 4.202 1.00 18.37 ? 396 GLU A O 1 ATOM 3160 C CB . GLU A 1 396 ? 27.518 31.687 3.206 1.00 21.57 ? 396 GLU A CB 1 ATOM 3161 C CG . GLU A 1 396 ? 26.002 31.592 3.134 1.00 26.77 ? 396 GLU A CG 1 ATOM 3162 C CD . GLU A 1 396 ? 25.518 30.288 2.517 1.00 26.96 ? 396 GLU A CD 1 ATOM 3163 O OE1 . GLU A 1 396 ? 25.985 29.924 1.415 1.00 35.08 ? 396 GLU A OE1 1 ATOM 3164 O OE2 . GLU A 1 396 ? 24.652 29.615 3.134 1.00 35.26 ? 396 GLU A OE2 1 ATOM 3165 N N . PHE A 1 397 ? 28.570 34.805 3.092 1.00 15.69 ? 397 PHE A N 1 ATOM 3166 C CA . PHE A 1 397 ? 28.326 36.194 2.743 1.00 13.15 ? 397 PHE A CA 1 ATOM 3167 C C . PHE A 1 397 ? 27.974 36.372 1.266 1.00 12.25 ? 397 PHE A C 1 ATOM 3168 O O . PHE A 1 397 ? 28.535 35.689 0.426 1.00 13.48 ? 397 PHE A O 1 ATOM 3169 C CB . PHE A 1 397 ? 29.552 37.032 3.106 1.00 13.51 ? 397 PHE A CB 1 ATOM 3170 C CG . PHE A 1 397 ? 29.831 37.063 4.586 1.00 11.69 ? 397 PHE A CG 1 ATOM 3171 C CD1 . PHE A 1 397 ? 29.011 37.777 5.426 1.00 10.87 ? 397 PHE A CD1 1 ATOM 3172 C CD2 . PHE A 1 397 ? 30.911 36.369 5.113 1.00 13.60 ? 397 PHE A CD2 1 ATOM 3173 C CE1 . PHE A 1 397 ? 29.231 37.804 6.793 1.00 11.56 ? 397 PHE A CE1 1 ATOM 3174 C CE2 . PHE A 1 397 ? 31.149 36.399 6.515 1.00 14.91 ? 397 PHE A CE2 1 ATOM 3175 C CZ . PHE A 1 397 ? 30.306 37.102 7.328 1.00 13.25 ? 397 PHE A CZ 1 ATOM 3176 N N . PRO A 1 398 ? 27.064 37.283 0.979 1.00 10.69 ? 398 PRO A N 1 ATOM 3177 C CA . PRO A 1 398 ? 26.696 37.572 -0.416 1.00 10.82 ? 398 PRO A CA 1 ATOM 3178 C C . PRO A 1 398 ? 27.788 38.314 -1.162 1.00 10.73 ? 398 PRO A C 1 ATOM 3179 O O . PRO A 1 398 ? 28.630 38.985 -0.554 1.00 10.37 ? 398 PRO A O 1 ATOM 3180 C CB . PRO A 1 398 ? 25.455 38.431 -0.266 1.00 12.33 ? 398 PRO A CB 1 ATOM 3181 C CG . PRO A 1 398 ? 25.683 39.181 1.032 1.00 11.56 ? 398 PRO A CG 1 ATOM 3182 C CD . PRO A 1 398 ? 26.310 38.134 1.911 1.00 11.77 ? 398 PRO A CD 1 ATOM 3183 N N . THR A 1 399 ? 27.741 38.187 -2.472 1.00 9.86 ? 399 THR A N 1 ATOM 3184 C CA . THR A 1 399 ? 28.628 38.928 -3.360 1.00 9.02 ? 399 THR A CA 1 ATOM 3185 C C . THR A 1 399 ? 27.888 40.152 -3.885 1.00 9.45 ? 399 THR A C 1 ATOM 3186 O O . THR A 1 399 ? 26.669 40.143 -4.030 1.00 10.00 ? 399 THR A O 1 ATOM 3187 C CB . THR A 1 399 ? 29.053 38.050 -4.525 1.00 10.16 ? 399 THR A CB 1 ATOM 3188 O OG1 . THR A 1 399 ? 27.871 37.592 -5.210 1.00 11.96 ? 399 THR A OG1 1 ATOM 3189 C CG2 . THR A 1 399 ? 29.831 36.806 -4.035 1.00 11.28 ? 399 THR A CG2 1 ATOM 3190 N N . LEU A 1 400 ? 28.652 41.220 -4.139 1.00 8.67 ? 400 LEU A N 1 ATOM 3191 C CA . LEU A 1 400 ? 28.042 42.481 -4.564 1.00 8.25 ? 400 LEU A CA 1 ATOM 3192 C C . LEU A 1 400 ? 28.957 43.172 -5.556 1.00 8.19 ? 400 LEU A C 1 ATOM 3193 O O . LEU A 1 400 ? 30.179 43.141 -5.426 1.00 7.86 ? 400 LEU A O 1 ATOM 3194 C CB . LEU A 1 400 ? 27.756 43.353 -3.338 1.00 8.35 ? 400 LEU A CB 1 ATOM 3195 C CG . LEU A 1 400 ? 27.101 44.739 -3.559 1.00 8.41 ? 400 LEU A CG 1 ATOM 3196 C CD1 . LEU A 1 400 ? 26.267 45.155 -2.339 1.00 10.43 ? 400 LEU A CD1 1 ATOM 3197 C CD2 . LEU A 1 400 ? 28.105 45.843 -3.901 1.00 9.28 ? 400 LEU A CD2 1 ATOM 3198 N N . SER A 1 401 ? 28.333 43.802 -6.558 1.00 7.59 ? 401 SER A N 1 ATOM 3199 C CA . SER A 1 401 ? 29.070 44.760 -7.403 1.00 7.53 ? 401 SER A CA 1 ATOM 3200 C C . SER A 1 401 ? 28.230 46.008 -7.592 1.00 7.18 ? 401 SER A C 1 ATOM 3201 O O . SER A 1 401 ? 27.001 45.990 -7.396 1.00 7.68 ? 401 SER A O 1 ATOM 3202 C CB . SER A 1 401 ? 29.478 44.165 -8.745 1.00 8.21 ? 401 SER A CB 1 ATOM 3203 O OG . SER A 1 401 ? 28.369 44.126 -9.621 1.00 8.81 ? 401 SER A OG 1 ATOM 3204 N N . GLY A 1 402 ? 28.924 47.103 -7.926 1.00 7.42 ? 402 GLY A N 1 ATOM 3205 C CA . GLY A 1 402 ? 28.276 48.387 -8.177 1.00 8.20 ? 402 GLY A CA 1 ATOM 3206 C C . GLY A 1 402 ? 28.877 49.462 -7.298 1.00 7.97 ? 402 GLY A C 1 ATOM 3207 O O . GLY A 1 402 ? 29.934 49.254 -6.665 1.00 8.90 ? 402 GLY A O 1 ATOM 3208 N N . ASP A 1 403 ? 28.249 50.623 -7.277 1.00 6.95 ? 403 ASP A N 1 ATOM 3209 C CA . ASP A 1 403 ? 28.716 51.732 -6.438 1.00 7.63 ? 403 ASP A CA 1 ATOM 3210 C C . ASP A 1 403 ? 27.596 52.193 -5.523 1.00 7.71 ? 403 ASP A C 1 ATOM 3211 O O . ASP A 1 403 ? 26.479 51.617 -5.505 1.00 8.47 ? 403 ASP A O 1 ATOM 3212 C CB . ASP A 1 403 ? 29.262 52.872 -7.295 1.00 7.76 ? 403 ASP A CB 1 ATOM 3213 C CG . ASP A 1 403 ? 28.189 53.640 -8.006 1.00 9.94 ? 403 ASP A CG 1 ATOM 3214 O OD1 . ASP A 1 403 ? 27.026 53.195 -8.034 1.00 13.02 ? 403 ASP A OD1 1 ATOM 3215 O OD2 . ASP A 1 403 ? 28.481 54.731 -8.516 1.00 13.22 ? 403 ASP A OD2 1 ATOM 3216 N N . PHE A 1 404 ? 27.892 53.202 -4.716 1.00 6.78 ? 404 PHE A N 1 ATOM 3217 C CA . PHE A 1 404 ? 26.965 53.773 -3.746 1.00 7.21 ? 404 PHE A CA 1 ATOM 3218 C C . PHE A 1 404 ? 26.874 55.290 -3.907 1.00 6.90 ? 404 PHE A C 1 ATOM 3219 O O . PHE A 1 404 ? 26.984 56.050 -2.945 1.00 8.30 ? 404 PHE A O 1 ATOM 3220 C CB . PHE A 1 404 ? 27.359 53.365 -2.301 1.00 7.64 ? 404 PHE A CB 1 ATOM 3221 C CG . PHE A 1 404 ? 27.316 51.872 -2.082 1.00 7.12 ? 404 PHE A CG 1 ATOM 3222 C CD1 . PHE A 1 404 ? 26.069 51.245 -1.939 1.00 7.08 ? 404 PHE A CD1 1 ATOM 3223 C CD2 . PHE A 1 404 ? 28.459 51.103 -2.093 1.00 6.99 ? 404 PHE A CD2 1 ATOM 3224 C CE1 . PHE A 1 404 ? 25.982 49.830 -1.802 1.00 8.15 ? 404 PHE A CE1 1 ATOM 3225 C CE2 . PHE A 1 404 ? 28.383 49.685 -1.921 1.00 7.85 ? 404 PHE A CE2 1 ATOM 3226 C CZ . PHE A 1 404 ? 27.130 49.065 -1.785 1.00 7.68 ? 404 PHE A CZ 1 ATOM 3227 N N . PHE A 1 405 ? 26.621 55.682 -5.163 1.00 7.44 ? 405 PHE A N 1 ATOM 3228 C CA . PHE A 1 405 ? 26.257 57.072 -5.495 1.00 6.98 ? 405 PHE A CA 1 ATOM 3229 C C . PHE A 1 405 ? 24.877 57.038 -6.140 1.00 7.54 ? 405 PHE A C 1 ATOM 3230 O O . PHE A 1 405 ? 24.567 56.051 -6.828 1.00 8.77 ? 405 PHE A O 1 ATOM 3231 C CB . PHE A 1 405 ? 27.245 57.693 -6.476 1.00 8.08 ? 405 PHE A CB 1 ATOM 3232 C CG . PHE A 1 405 ? 28.654 57.775 -5.948 1.00 7.69 ? 405 PHE A CG 1 ATOM 3233 C CD1 . PHE A 1 405 ? 28.915 58.578 -4.862 1.00 7.86 ? 405 PHE A CD1 1 ATOM 3234 C CD2 . PHE A 1 405 ? 29.692 57.074 -6.541 1.00 8.68 ? 405 PHE A CD2 1 ATOM 3235 C CE1 . PHE A 1 405 ? 30.225 58.682 -4.315 1.00 7.50 ? 405 PHE A CE1 1 ATOM 3236 C CE2 . PHE A 1 405 ? 30.999 57.160 -6.016 1.00 8.53 ? 405 PHE A CE2 1 ATOM 3237 C CZ . PHE A 1 405 ? 31.256 57.974 -4.889 1.00 8.25 ? 405 PHE A CZ 1 ATOM 3238 N N . THR A 1 406 ? 24.065 58.086 -6.017 1.00 8.04 ? 406 THR A N 1 ATOM 3239 C CA . THR A 1 406 ? 24.304 59.283 -5.229 1.00 7.66 ? 406 THR A CA 1 ATOM 3240 C C . THR A 1 406 ? 23.678 59.172 -3.850 1.00 8.24 ? 406 THR A C 1 ATOM 3241 O O . THR A 1 406 ? 22.514 58.744 -3.696 1.00 8.68 ? 406 THR A O 1 ATOM 3242 C CB . THR A 1 406 ? 23.745 60.501 -6.014 1.00 7.94 ? 406 THR A CB 1 ATOM 3243 O OG1 . THR A 1 406 ? 24.669 60.728 -7.082 1.00 8.23 ? 406 THR A OG1 1 ATOM 3244 C CG2 . THR A 1 406 ? 23.676 61.770 -5.184 1.00 9.09 ? 406 THR A CG2 1 ATOM 3245 N N . TYR A 1 407 ? 24.459 59.527 -2.846 1.00 7.93 ? 407 TYR A N 1 ATOM 3246 C CA . TYR A 1 407 ? 24.051 59.431 -1.458 1.00 7.32 ? 407 TYR A CA 1 ATOM 3247 C C . TYR A 1 407 ? 22.911 60.389 -1.159 1.00 7.92 ? 407 TYR A C 1 ATOM 3248 O O . TYR A 1 407 ? 22.909 61.510 -1.606 1.00 8.07 ? 407 TYR A O 1 ATOM 3249 C CB . TYR A 1 407 ? 25.259 59.778 -0.605 1.00 7.78 ? 407 TYR A CB 1 ATOM 3250 C CG . TYR A 1 407 ? 25.071 59.910 0.891 1.00 7.71 ? 407 TYR A CG 1 ATOM 3251 C CD1 . TYR A 1 407 ? 24.605 58.861 1.676 1.00 8.78 ? 407 TYR A CD1 1 ATOM 3252 C CD2 . TYR A 1 407 ? 25.476 61.053 1.527 1.00 8.07 ? 407 TYR A CD2 1 ATOM 3253 C CE1 . TYR A 1 407 ? 24.512 59.003 3.047 1.00 9.40 ? 407 TYR A CE1 1 ATOM 3254 C CE2 . TYR A 1 407 ? 25.388 61.200 2.873 1.00 9.71 ? 407 TYR A CE2 1 ATOM 3255 C CZ . TYR A 1 407 ? 24.911 60.178 3.638 1.00 9.11 ? 407 TYR A CZ 1 ATOM 3256 O OH . TYR A 1 407 ? 24.867 60.356 5.000 1.00 10.28 ? 407 TYR A OH 1 ATOM 3257 N N . ALA A 1 408 ? 21.953 59.911 -0.379 1.00 8.81 ? 408 ALA A N 1 ATOM 3258 C CA . ALA A 1 408 ? 20.983 60.785 0.302 1.00 9.41 ? 408 ALA A CA 1 ATOM 3259 C C . ALA A 1 408 ? 20.900 60.335 1.736 1.00 9.27 ? 408 ALA A C 1 ATOM 3260 O O . ALA A 1 408 ? 20.793 59.114 1.989 1.00 9.40 ? 408 ALA A O 1 ATOM 3261 C CB . ALA A 1 408 ? 19.568 60.699 -0.362 1.00 10.06 ? 408 ALA A CB 1 ATOM 3262 N N . ASP A 1 409 ? 20.980 61.270 2.676 1.00 8.79 ? 409 ASP A N 1 ATOM 3263 C CA . ASP A 1 409 ? 20.914 60.912 4.100 1.00 9.94 ? 409 ASP A CA 1 ATOM 3264 C C . ASP A 1 409 ? 19.482 60.995 4.658 1.00 10.41 ? 409 ASP A C 1 ATOM 3265 O O . ASP A 1 409 ? 19.213 60.409 5.715 1.00 11.13 ? 409 ASP A O 1 ATOM 3266 C CB . ASP A 1 409 ? 21.891 61.730 4.969 1.00 10.08 ? 409 ASP A CB 1 ATOM 3267 C CG . ASP A 1 409 ? 21.698 63.238 4.888 1.00 9.60 ? 409 ASP A CG 1 ATOM 3268 O OD1 . ASP A 1 409 ? 21.045 63.766 3.965 1.00 10.11 ? 409 ASP A OD1 1 ATOM 3269 O OD2 . ASP A 1 409 ? 22.254 63.956 5.755 1.00 11.95 ? 409 ASP A OD2 1 ATOM 3270 N N . ARG A 1 410 ? 18.589 61.680 3.935 1.00 10.18 ? 410 ARG A N 1 ATOM 3271 C CA . ARG A 1 410 ? 17.186 61.813 4.379 1.00 11.55 ? 410 ARG A CA 1 ATOM 3272 C C . ARG A 1 410 ? 16.384 62.445 3.249 1.00 12.11 ? 410 ARG A C 1 ATOM 3273 O O . ARG A 1 410 ? 16.919 63.189 2.398 1.00 12.33 ? 410 ARG A O 1 ATOM 3274 C CB . ARG A 1 410 ? 17.067 62.606 5.679 1.00 11.64 ? 410 ARG A CB 1 ATOM 3275 C CG . ARG A 1 410 ? 17.553 64.063 5.630 1.00 13.42 ? 410 ARG A CG 1 ATOM 3276 C CD . ARG A 1 410 ? 17.560 64.680 7.014 1.00 13.52 ? 410 ARG A CD 1 ATOM 3277 N NE . ARG A 1 410 ? 18.283 65.950 7.142 1.00 15.16 ? 410 ARG A NE 1 ATOM 3278 C CZ . ARG A 1 410 ? 17.747 67.152 6.959 1.00 17.20 ? 410 ARG A CZ 1 ATOM 3279 N NH1 . ARG A 1 410 ? 16.469 67.271 6.566 1.00 18.30 ? 410 ARG A NH1 1 ATOM 3280 N NH2 . ARG A 1 410 ? 18.488 68.240 7.114 1.00 17.91 ? 410 ARG A NH2 1 ATOM 3281 N N . SER A 1 411 ? 15.088 62.091 3.223 1.00 12.79 ? 411 SER A N 1 ATOM 3282 C CA A SER A 1 411 ? 14.099 62.616 2.279 0.50 13.58 ? 411 SER A CA 1 ATOM 3283 C CA B SER A 1 411 ? 14.131 62.698 2.308 0.50 13.60 ? 411 SER A CA 1 ATOM 3284 C C . SER A 1 411 ? 14.663 62.717 0.866 1.00 12.98 ? 411 SER A C 1 ATOM 3285 O O . SER A 1 411 ? 15.144 61.704 0.333 1.00 13.33 ? 411 SER A O 1 ATOM 3286 C CB A SER A 1 411 ? 13.462 63.910 2.784 0.50 14.60 ? 411 SER A CB 1 ATOM 3287 C CB B SER A 1 411 ? 13.782 64.103 2.802 0.50 14.77 ? 411 SER A CB 1 ATOM 3288 O OG A SER A 1 411 ? 14.434 64.881 3.093 0.50 15.99 ? 411 SER A OG 1 ATOM 3289 O OG B SER A 1 411 ? 12.697 64.633 2.078 0.50 16.75 ? 411 SER A OG 1 ATOM 3290 N N . ASP A 1 412 ? 14.583 63.895 0.230 1.00 12.31 ? 412 ASP A N 1 ATOM 3291 C CA . ASP A 1 412 ? 15.103 64.097 -1.116 1.00 11.09 ? 412 ASP A CA 1 ATOM 3292 C C . ASP A 1 412 ? 16.450 64.845 -1.112 1.00 10.00 ? 412 ASP A C 1 ATOM 3293 O O . ASP A 1 412 ? 16.825 65.425 -2.143 1.00 10.30 ? 412 ASP A O 1 ATOM 3294 C CB . ASP A 1 412 ? 14.108 64.910 -1.959 1.00 12.12 ? 412 ASP A CB 1 ATOM 3295 C CG . ASP A 1 412 ? 13.916 66.331 -1.441 1.00 11.56 ? 412 ASP A CG 1 ATOM 3296 O OD1 . ASP A 1 412 ? 14.387 66.673 -0.339 1.00 12.30 ? 412 ASP A OD1 1 ATOM 3297 O OD2 . ASP A 1 412 ? 13.268 67.186 -2.116 1.00 15.16 ? 412 ASP A OD2 1 ATOM 3298 N N . ASN A 1 413 ? 17.148 64.813 0.018 1.00 10.01 ? 413 ASN A N 1 ATOM 3299 C CA . ASN A 1 413 ? 18.420 65.557 0.161 1.00 9.37 ? 413 ASN A CA 1 ATOM 3300 C C . ASN A 1 413 ? 19.580 64.686 -0.393 1.00 8.82 ? 413 ASN A C 1 ATOM 3301 O O . ASN A 1 413 ? 20.258 63.997 0.370 1.00 9.43 ? 413 ASN A O 1 ATOM 3302 C CB . ASN A 1 413 ? 18.671 65.873 1.624 1.00 10.73 ? 413 ASN A CB 1 ATOM 3303 C CG . ASN A 1 413 ? 17.720 66.936 2.230 1.00 9.97 ? 413 ASN A CG 1 ATOM 3304 O OD1 . ASN A 1 413 ? 17.990 67.397 3.321 1.00 12.62 ? 413 ASN A OD1 1 ATOM 3305 N ND2 . ASN A 1 413 ? 16.637 67.327 1.519 1.00 11.03 ? 413 ASN A ND2 1 ATOM 3306 N N . TYR A 1 414 ? 19.732 64.728 -1.707 1.00 8.46 ? 414 TYR A N 1 ATOM 3307 C CA . TYR A 1 414 ? 20.810 64.047 -2.446 1.00 8.91 ? 414 TYR A CA 1 ATOM 3308 C C . TYR A 1 414 ? 22.045 64.932 -2.504 1.00 8.87 ? 414 TYR A C 1 ATOM 3309 O O . TYR A 1 414 ? 21.966 66.119 -2.837 1.00 8.44 ? 414 TYR A O 1 ATOM 3310 C CB . TYR A 1 414 ? 20.351 63.705 -3.862 1.00 9.49 ? 414 TYR A CB 1 ATOM 3311 C CG . TYR A 1 414 ? 19.345 62.550 -3.862 1.00 9.21 ? 414 TYR A CG 1 ATOM 3312 C CD1 . TYR A 1 414 ? 17.975 62.770 -3.632 1.00 10.27 ? 414 TYR A CD1 1 ATOM 3313 C CD2 . TYR A 1 414 ? 19.785 61.240 -4.033 1.00 9.68 ? 414 TYR A CD2 1 ATOM 3314 C CE1 . TYR A 1 414 ? 17.076 61.687 -3.591 1.00 10.09 ? 414 TYR A CE1 1 ATOM 3315 C CE2 . TYR A 1 414 ? 18.888 60.158 -4.004 1.00 10.04 ? 414 TYR A CE2 1 ATOM 3316 C CZ . TYR A 1 414 ? 17.548 60.412 -3.785 1.00 10.24 ? 414 TYR A CZ 1 ATOM 3317 O OH . TYR A 1 414 ? 16.682 59.311 -3.763 1.00 10.39 ? 414 TYR A OH 1 ATOM 3318 N N . TRP A 1 415 ? 23.183 64.320 -2.199 1.00 8.77 ? 415 TRP A N 1 ATOM 3319 C CA . TRP A 1 415 ? 24.429 65.052 -2.077 1.00 7.76 ? 415 TRP A CA 1 ATOM 3320 C C . TRP A 1 415 ? 25.142 65.083 -3.423 1.00 9.00 ? 415 TRP A C 1 ATOM 3321 O O . TRP A 1 415 ? 26.277 64.601 -3.561 1.00 10.33 ? 415 TRP A O 1 ATOM 3322 C CB . TRP A 1 415 ? 25.292 64.370 -1.030 1.00 7.61 ? 415 TRP A CB 1 ATOM 3323 C CG . TRP A 1 415 ? 24.746 64.415 0.368 1.00 7.82 ? 415 TRP A CG 1 ATOM 3324 C CD1 . TRP A 1 415 ? 23.421 64.172 0.796 1.00 8.37 ? 415 TRP A CD1 1 ATOM 3325 C CD2 . TRP A 1 415 ? 25.508 64.663 1.554 1.00 7.72 ? 415 TRP A CD2 1 ATOM 3326 N NE1 . TRP A 1 415 ? 23.376 64.285 2.161 1.00 9.17 ? 415 TRP A NE1 1 ATOM 3327 C CE2 . TRP A 1 415 ? 24.636 64.555 2.660 1.00 8.50 ? 415 TRP A CE2 1 ATOM 3328 C CE3 . TRP A 1 415 ? 26.877 64.943 1.802 1.00 8.73 ? 415 TRP A CE3 1 ATOM 3329 C CZ2 . TRP A 1 415 ? 25.066 64.746 3.974 1.00 9.32 ? 415 TRP A CZ2 1 ATOM 3330 C CZ3 . TRP A 1 415 ? 27.301 65.141 3.079 1.00 9.36 ? 415 TRP A CZ3 1 ATOM 3331 C CH2 . TRP A 1 415 ? 26.410 65.015 4.174 1.00 9.16 ? 415 TRP A CH2 1 ATOM 3332 N N . SER A 1 416 ? 24.512 65.659 -4.434 1.00 7.60 ? 416 SER A N 1 ATOM 3333 C CA . SER A 1 416 ? 25.149 65.780 -5.729 1.00 8.24 ? 416 SER A CA 1 ATOM 3334 C C . SER A 1 416 ? 25.737 67.177 -5.944 1.00 7.29 ? 416 SER A C 1 ATOM 3335 O O . SER A 1 416 ? 26.407 67.387 -6.941 1.00 7.85 ? 416 SER A O 1 ATOM 3336 C CB . SER A 1 416 ? 24.211 65.363 -6.865 1.00 7.59 ? 416 SER A CB 1 ATOM 3337 O OG . SER A 1 416 ? 22.916 65.929 -6.670 1.00 8.93 ? 416 SER A OG 1 ATOM 3338 N N . GLY A 1 417 ? 25.532 68.103 -5.010 1.00 6.83 ? 417 GLY A N 1 ATOM 3339 C CA . GLY A 1 417 ? 26.100 69.448 -5.169 1.00 8.01 ? 417 GLY A CA 1 ATOM 3340 C C . GLY A 1 417 ? 27.625 69.422 -5.106 1.00 5.99 ? 417 GLY A C 1 ATOM 3341 O O . GLY A 1 417 ? 28.283 70.141 -5.861 1.00 7.05 ? 417 GLY A O 1 ATOM 3342 N N . TYR A 1 418 ? 28.185 68.596 -4.220 1.00 6.06 ? 418 TYR A N 1 ATOM 3343 C CA . TYR A 1 418 ? 29.644 68.624 -4.040 1.00 5.91 ? 418 TYR A CA 1 ATOM 3344 C C . TYR A 1 418 ? 30.386 67.988 -5.199 1.00 6.35 ? 418 TYR A C 1 ATOM 3345 O O . TYR A 1 418 ? 31.635 68.038 -5.251 1.00 6.57 ? 418 TYR A O 1 ATOM 3346 C CB . TYR A 1 418 ? 30.025 67.963 -2.728 1.00 6.56 ? 418 TYR A CB 1 ATOM 3347 C CG . TYR A 1 418 ? 30.143 66.445 -2.775 1.00 6.95 ? 418 TYR A CG 1 ATOM 3348 C CD1 . TYR A 1 418 ? 29.025 65.620 -2.623 1.00 8.02 ? 418 TYR A CD1 1 ATOM 3349 C CD2 . TYR A 1 418 ? 31.383 65.838 -2.956 1.00 6.64 ? 418 TYR A CD2 1 ATOM 3350 C CE1 . TYR A 1 418 ? 29.142 64.217 -2.644 1.00 6.92 ? 418 TYR A CE1 1 ATOM 3351 C CE2 . TYR A 1 418 ? 31.524 64.466 -2.989 1.00 6.45 ? 418 TYR A CE2 1 ATOM 3352 C CZ . TYR A 1 418 ? 30.396 63.669 -2.821 1.00 5.99 ? 418 TYR A CZ 1 ATOM 3353 O OH . TYR A 1 418 ? 30.570 62.301 -2.824 1.00 7.34 ? 418 TYR A OH 1 ATOM 3354 N N . TYR A 1 419 ? 29.673 67.416 -6.169 1.00 5.58 ? 419 TYR A N 1 ATOM 3355 C CA . TYR A 1 419 ? 30.337 66.978 -7.393 1.00 5.66 ? 419 TYR A CA 1 ATOM 3356 C C . TYR A 1 419 ? 30.867 68.192 -8.193 1.00 5.84 ? 419 TYR A C 1 ATOM 3357 O O . TYR A 1 419 ? 31.698 68.027 -9.072 1.00 6.51 ? 419 TYR A O 1 ATOM 3358 C CB . TYR A 1 419 ? 29.416 66.180 -8.297 1.00 6.43 ? 419 TYR A CB 1 ATOM 3359 C CG . TYR A 1 419 ? 28.770 64.976 -7.666 1.00 5.16 ? 419 TYR A CG 1 ATOM 3360 C CD1 . TYR A 1 419 ? 29.345 64.298 -6.572 1.00 6.77 ? 419 TYR A CD1 1 ATOM 3361 C CD2 . TYR A 1 419 ? 27.589 64.445 -8.221 1.00 6.82 ? 419 TYR A CD2 1 ATOM 3362 C CE1 . TYR A 1 419 ? 28.760 63.145 -6.016 1.00 6.89 ? 419 TYR A CE1 1 ATOM 3363 C CE2 . TYR A 1 419 ? 26.986 63.331 -7.659 1.00 7.07 ? 419 TYR A CE2 1 ATOM 3364 C CZ . TYR A 1 419 ? 27.590 62.683 -6.579 1.00 6.53 ? 419 TYR A CZ 1 ATOM 3365 O OH . TYR A 1 419 ? 27.028 61.545 -6.025 1.00 7.13 ? 419 TYR A OH 1 ATOM 3366 N N . THR A 1 420 ? 30.389 69.400 -7.851 1.00 6.01 ? 420 THR A N 1 ATOM 3367 C CA . THR A 1 420 ? 30.775 70.629 -8.557 1.00 7.21 ? 420 THR A CA 1 ATOM 3368 C C . THR A 1 420 ? 31.328 71.723 -7.660 1.00 7.11 ? 420 THR A C 1 ATOM 3369 O O . THR A 1 420 ? 32.083 72.557 -8.153 1.00 7.74 ? 420 THR A O 1 ATOM 3370 C CB . THR A 1 420 ? 29.533 71.138 -9.351 1.00 7.85 ? 420 THR A CB 1 ATOM 3371 O OG1 . THR A 1 420 ? 29.094 70.096 -10.233 1.00 8.35 ? 420 THR A OG1 1 ATOM 3372 C CG2 . THR A 1 420 ? 29.837 72.344 -10.232 1.00 8.94 ? 420 THR A CG2 1 ATOM 3373 N N . SER A 1 421 ? 30.968 71.744 -6.385 1.00 6.46 ? 421 SER A N 1 ATOM 3374 C CA . SER A 1 421 ? 31.330 72.873 -5.544 1.00 7.20 ? 421 SER A CA 1 ATOM 3375 C C . SER A 1 421 ? 32.814 73.191 -5.589 1.00 7.59 ? 421 SER A C 1 ATOM 3376 O O . SER A 1 421 ? 33.673 72.306 -5.521 1.00 6.92 ? 421 SER A O 1 ATOM 3377 C CB . SER A 1 421 ? 30.961 72.568 -4.110 1.00 6.74 ? 421 SER A CB 1 ATOM 3378 O OG . SER A 1 421 ? 29.544 72.405 -4.013 1.00 8.00 ? 421 SER A OG 1 ATOM 3379 N N . ARG A 1 422 ? 33.111 74.489 -5.639 1.00 6.25 ? 422 ARG A N 1 ATOM 3380 C CA . ARG A 1 422 ? 34.511 74.992 -5.694 1.00 6.80 ? 422 ARG A CA 1 ATOM 3381 C C . ARG A 1 422 ? 35.262 74.370 -6.875 1.00 7.12 ? 422 ARG A C 1 ATOM 3382 O O . ARG A 1 422 ? 36.278 73.663 -6.720 1.00 6.97 ? 422 ARG A O 1 ATOM 3383 C CB . ARG A 1 422 ? 35.263 74.786 -4.370 1.00 7.53 ? 422 ARG A CB 1 ATOM 3384 C CG . ARG A 1 422 ? 34.984 75.871 -3.293 1.00 8.58 ? 422 ARG A CG 1 ATOM 3385 C CD . ARG A 1 422 ? 33.518 75.981 -2.829 1.00 9.08 ? 422 ARG A CD 1 ATOM 3386 N NE . ARG A 1 422 ? 33.502 76.957 -1.733 1.00 9.15 ? 422 ARG A NE 1 ATOM 3387 C CZ . ARG A 1 422 ? 33.626 76.665 -0.446 1.00 9.98 ? 422 ARG A CZ 1 ATOM 3388 N NH1 . ARG A 1 422 ? 33.573 75.420 -0.007 1.00 8.87 ? 422 ARG A NH1 1 ATOM 3389 N NH2 . ARG A 1 422 ? 33.770 77.665 0.432 1.00 9.87 ? 422 ARG A NH2 1 ATOM 3390 N N . PRO A 1 423 ? 34.761 74.575 -8.079 1.00 6.80 ? 423 PRO A N 1 ATOM 3391 C CA . PRO A 1 423 ? 35.345 73.920 -9.247 1.00 6.56 ? 423 PRO A CA 1 ATOM 3392 C C . PRO A 1 423 ? 36.751 74.419 -9.593 1.00 6.57 ? 423 PRO A C 1 ATOM 3393 O O . PRO A 1 423 ? 37.475 73.673 -10.265 1.00 7.00 ? 423 PRO A O 1 ATOM 3394 C CB . PRO A 1 423 ? 34.320 74.220 -10.363 1.00 7.05 ? 423 PRO A CB 1 ATOM 3395 C CG . PRO A 1 423 ? 33.758 75.539 -9.957 1.00 8.15 ? 423 PRO A CG 1 ATOM 3396 C CD . PRO A 1 423 ? 33.600 75.421 -8.444 1.00 7.35 ? 423 PRO A CD 1 ATOM 3397 N N . TYR A 1 424 ? 37.155 75.623 -9.167 1.00 7.09 ? 424 TYR A N 1 ATOM 3398 C CA . TYR A 1 424 ? 38.522 76.061 -9.431 1.00 6.63 ? 424 TYR A CA 1 ATOM 3399 C C . TYR A 1 424 ? 39.473 75.046 -8.822 1.00 6.13 ? 424 TYR A C 1 ATOM 3400 O O . TYR A 1 424 ? 40.467 74.656 -9.456 1.00 6.62 ? 424 TYR A O 1 ATOM 3401 C CB . TYR A 1 424 ? 38.744 77.436 -8.820 1.00 7.46 ? 424 TYR A CB 1 ATOM 3402 C CG . TYR A 1 424 ? 40.134 77.991 -9.057 1.00 7.86 ? 424 TYR A CG 1 ATOM 3403 C CD1 . TYR A 1 424 ? 41.170 77.735 -8.161 1.00 8.55 ? 424 TYR A CD1 1 ATOM 3404 C CD2 . TYR A 1 424 ? 40.392 78.777 -10.183 1.00 10.12 ? 424 TYR A CD2 1 ATOM 3405 C CE1 . TYR A 1 424 ? 42.471 78.255 -8.417 1.00 10.47 ? 424 TYR A CE1 1 ATOM 3406 C CE2 . TYR A 1 424 ? 41.635 79.288 -10.414 1.00 11.46 ? 424 TYR A CE2 1 ATOM 3407 C CZ . TYR A 1 424 ? 42.663 79.038 -9.542 1.00 9.63 ? 424 TYR A CZ 1 ATOM 3408 O OH . TYR A 1 424 ? 43.911 79.589 -9.860 1.00 13.28 ? 424 TYR A OH 1 ATOM 3409 N N . HIS A 1 425 ? 39.201 74.616 -7.591 1.00 6.28 ? 425 HIS A N 1 ATOM 3410 C CA . HIS A 1 425 ? 40.144 73.727 -6.880 1.00 6.31 ? 425 HIS A CA 1 ATOM 3411 C C . HIS A 1 425 ? 40.044 72.300 -7.350 1.00 6.72 ? 425 HIS A C 1 ATOM 3412 O O . HIS A 1 425 ? 41.019 71.551 -7.322 1.00 6.32 ? 425 HIS A O 1 ATOM 3413 C CB . HIS A 1 425 ? 39.920 73.870 -5.368 1.00 7.39 ? 425 HIS A CB 1 ATOM 3414 C CG . HIS A 1 425 ? 40.004 75.294 -4.961 1.00 8.03 ? 425 HIS A CG 1 ATOM 3415 N ND1 . HIS A 1 425 ? 38.919 76.143 -5.022 1.00 9.30 ? 425 HIS A ND1 1 ATOM 3416 C CD2 . HIS A 1 425 ? 41.082 76.064 -4.668 1.00 9.15 ? 425 HIS A CD2 1 ATOM 3417 C CE1 . HIS A 1 425 ? 39.309 77.369 -4.707 1.00 9.41 ? 425 HIS A CE1 1 ATOM 3418 N NE2 . HIS A 1 425 ? 40.613 77.350 -4.482 1.00 9.73 ? 425 HIS A NE2 1 ATOM 3419 N N . LYS A 1 426 ? 38.864 71.894 -7.821 1.00 6.36 ? 426 LYS A N 1 ATOM 3420 C CA . LYS A 1 426 ? 38.717 70.601 -8.497 1.00 6.19 ? 426 LYS A CA 1 ATOM 3421 C C . LYS A 1 426 ? 39.607 70.538 -9.729 1.00 6.23 ? 426 LYS A C 1 ATOM 3422 O O . LYS A 1 426 ? 40.223 69.506 -10.012 1.00 6.41 ? 426 LYS A O 1 ATOM 3423 C CB . LYS A 1 426 ? 37.238 70.382 -8.877 1.00 6.81 ? 426 LYS A CB 1 ATOM 3424 C CG . LYS A 1 426 ? 36.344 69.983 -7.695 1.00 6.89 ? 426 LYS A CG 1 ATOM 3425 C CD . LYS A 1 426 ? 34.850 70.035 -8.074 1.00 7.38 ? 426 LYS A CD 1 ATOM 3426 C CE . LYS A 1 426 ? 33.971 69.171 -7.161 1.00 7.87 ? 426 LYS A CE 1 ATOM 3427 N NZ . LYS A 1 426 ? 33.928 69.595 -5.726 1.00 7.32 ? 426 LYS A NZ 1 ATOM 3428 N N . ARG A 1 427 ? 39.642 71.621 -10.507 1.00 6.08 ? 427 ARG A N 1 ATOM 3429 C CA . ARG A 1 427 ? 40.494 71.647 -11.661 1.00 6.75 ? 427 ARG A CA 1 ATOM 3430 C C . ARG A 1 427 ? 41.977 71.652 -11.242 1.00 6.94 ? 427 ARG A C 1 ATOM 3431 O O . ARG A 1 427 ? 42.795 70.957 -11.816 1.00 5.68 ? 427 ARG A O 1 ATOM 3432 C CB . ARG A 1 427 ? 40.137 72.870 -12.542 1.00 6.65 ? 427 ARG A CB 1 ATOM 3433 C CG . ARG A 1 427 ? 41.103 73.108 -13.669 1.00 7.79 ? 427 ARG A CG 1 ATOM 3434 C CD . ARG A 1 427 ? 41.182 72.026 -14.723 1.00 10.38 ? 427 ARG A CD 1 ATOM 3435 N NE . ARG A 1 427 ? 42.219 72.402 -15.701 1.00 10.22 ? 427 ARG A NE 1 ATOM 3436 C CZ . ARG A 1 427 ? 43.040 71.580 -16.266 1.00 10.16 ? 427 ARG A CZ 1 ATOM 3437 N NH1 . ARG A 1 427 ? 42.973 70.273 -16.067 1.00 10.92 ? 427 ARG A NH1 1 ATOM 3438 N NH2 . ARG A 1 427 ? 43.989 72.089 -17.079 1.00 11.30 ? 427 ARG A NH2 1 ATOM 3439 N N . MET A 1 428 ? 42.296 72.455 -10.230 1.00 6.29 ? 428 MET A N 1 ATOM 3440 C CA . MET A 1 428 ? 43.669 72.506 -9.728 1.00 6.48 ? 428 MET A CA 1 ATOM 3441 C C . MET A 1 428 ? 44.173 71.126 -9.283 1.00 6.23 ? 428 MET A C 1 ATOM 3442 O O . MET A 1 428 ? 45.334 70.776 -9.517 1.00 6.58 ? 428 MET A O 1 ATOM 3443 C CB . MET A 1 428 ? 43.723 73.492 -8.574 1.00 7.57 ? 428 MET A CB 1 ATOM 3444 C CG . MET A 1 428 ? 45.169 73.880 -8.180 1.00 7.57 ? 428 MET A CG 1 ATOM 3445 S SD . MET A 1 428 ? 45.085 75.189 -6.905 1.00 9.25 ? 428 MET A SD 1 ATOM 3446 C CE . MET A 1 428 ? 46.808 75.707 -6.844 1.00 9.77 ? 428 MET A CE 1 ATOM 3447 N N . ASP A 1 429 ? 43.293 70.308 -8.688 1.00 6.50 ? 429 ASP A N 1 ATOM 3448 C CA . ASP A 1 429 ? 43.636 68.947 -8.290 1.00 6.09 ? 429 ASP A CA 1 ATOM 3449 C C . ASP A 1 429 ? 44.214 68.172 -9.468 1.00 6.30 ? 429 ASP A C 1 ATOM 3450 O O . ASP A 1 429 ? 45.204 67.454 -9.328 1.00 6.30 ? 429 ASP A O 1 ATOM 3451 C CB . ASP A 1 429 ? 42.373 68.240 -7.786 1.00 7.36 ? 429 ASP A CB 1 ATOM 3452 C CG . ASP A 1 429 ? 42.634 66.789 -7.486 1.00 6.42 ? 429 ASP A CG 1 ATOM 3453 O OD1 . ASP A 1 429 ? 43.151 66.524 -6.355 1.00 7.80 ? 429 ASP A OD1 1 ATOM 3454 O OD2 . ASP A 1 429 ? 42.342 65.883 -8.300 1.00 7.24 ? 429 ASP A OD2 1 ATOM 3455 N N . ARG A 1 430 ? 43.540 68.272 -10.625 1.00 5.86 ? 430 ARG A N 1 ATOM 3456 C CA . ARG A 1 430 ? 43.981 67.489 -11.787 1.00 5.98 ? 430 ARG A CA 1 ATOM 3457 C C . ARG A 1 430 ? 45.301 68.017 -12.364 1.00 5.72 ? 430 ARG A C 1 ATOM 3458 O O . ARG A 1 430 ? 46.133 67.226 -12.837 1.00 6.76 ? 430 ARG A O 1 ATOM 3459 C CB . ARG A 1 430 ? 42.899 67.508 -12.868 1.00 6.21 ? 430 ARG A CB 1 ATOM 3460 C CG . ARG A 1 430 ? 41.656 66.763 -12.455 1.00 7.15 ? 430 ARG A CG 1 ATOM 3461 C CD . ARG A 1 430 ? 41.911 65.317 -12.004 1.00 6.74 ? 430 ARG A CD 1 ATOM 3462 N NE . ARG A 1 430 ? 40.656 64.549 -12.039 1.00 6.69 ? 430 ARG A NE 1 ATOM 3463 C CZ . ARG A 1 430 ? 39.960 64.212 -10.971 1.00 6.20 ? 430 ARG A CZ 1 ATOM 3464 N NH1 . ARG A 1 430 ? 40.361 64.547 -9.751 1.00 6.65 ? 430 ARG A NH1 1 ATOM 3465 N NH2 . ARG A 1 430 ? 38.837 63.515 -11.097 1.00 6.63 ? 430 ARG A NH2 1 ATOM 3466 N N . VAL A 1 431 ? 45.494 69.334 -12.311 1.00 5.82 ? 431 VAL A N 1 ATOM 3467 C CA . VAL A 1 431 ? 46.775 69.916 -12.753 1.00 6.66 ? 431 VAL A CA 1 ATOM 3468 C C . VAL A 1 431 ? 47.903 69.407 -11.849 1.00 6.84 ? 431 VAL A C 1 ATOM 3469 O O . VAL A 1 431 ? 48.944 68.925 -12.326 1.00 6.75 ? 431 VAL A O 1 ATOM 3470 C CB . VAL A 1 431 ? 46.654 71.439 -12.747 1.00 6.77 ? 431 VAL A CB 1 ATOM 3471 C CG1 . VAL A 1 431 ? 48.008 72.079 -13.061 1.00 8.62 ? 431 VAL A CG1 1 ATOM 3472 C CG2 . VAL A 1 431 ? 45.552 71.878 -13.765 1.00 7.94 ? 431 VAL A CG2 1 ATOM 3473 N N . LEU A 1 432 ? 47.707 69.507 -10.543 1.00 6.07 ? 432 LEU A N 1 ATOM 3474 C CA . LEU A 1 432 ? 48.752 69.085 -9.607 1.00 6.19 ? 432 LEU A CA 1 ATOM 3475 C C . LEU A 1 432 ? 48.962 67.569 -9.699 1.00 5.91 ? 432 LEU A C 1 ATOM 3476 O O . LEU A 1 432 ? 50.102 67.096 -9.596 1.00 6.68 ? 432 LEU A O 1 ATOM 3477 C CB . LEU A 1 432 ? 48.427 69.553 -8.193 1.00 7.32 ? 432 LEU A CB 1 ATOM 3478 C CG . LEU A 1 432 ? 49.402 69.169 -7.104 1.00 7.90 ? 432 LEU A CG 1 ATOM 3479 C CD1 . LEU A 1 432 ? 50.835 69.644 -7.382 1.00 7.47 ? 432 LEU A CD1 1 ATOM 3480 C CD2 . LEU A 1 432 ? 48.945 69.771 -5.785 1.00 7.78 ? 432 LEU A CD2 1 ATOM 3481 N N . MET A 1 433 ? 47.894 66.792 -9.929 1.00 5.39 ? 433 MET A N 1 ATOM 3482 C CA . MET A 1 433 ? 48.048 65.353 -10.122 1.00 6.14 ? 433 MET A CA 1 ATOM 3483 C C . MET A 1 433 ? 49.104 65.048 -11.173 1.00 6.15 ? 433 MET A C 1 ATOM 3484 O O . MET A 1 433 ? 49.987 64.194 -10.986 1.00 6.25 ? 433 MET A O 1 ATOM 3485 C CB . MET A 1 433 ? 46.716 64.760 -10.605 1.00 6.57 ? 433 MET A CB 1 ATOM 3486 C CG . MET A 1 433 ? 46.793 63.256 -10.871 1.00 7.03 ? 433 MET A CG 1 ATOM 3487 S SD . MET A 1 433 ? 45.229 62.579 -11.531 1.00 9.43 ? 433 MET A SD 1 ATOM 3488 C CE . MET A 1 433 ? 45.254 63.282 -13.184 1.00 10.95 ? 433 MET A CE 1 ATOM 3489 N N . HIS A 1 434 ? 48.992 65.733 -12.305 1.00 5.90 ? 434 HIS A N 1 ATOM 3490 C CA . HIS A 1 434 ? 49.907 65.504 -13.409 1.00 5.46 ? 434 HIS A CA 1 ATOM 3491 C C . HIS A 1 434 ? 51.317 66.007 -13.099 1.00 5.98 ? 434 HIS A C 1 ATOM 3492 O O . HIS A 1 434 ? 52.300 65.332 -13.440 1.00 6.91 ? 434 HIS A O 1 ATOM 3493 C CB . HIS A 1 434 ? 49.356 66.203 -14.668 1.00 7.19 ? 434 HIS A CB 1 ATOM 3494 C CG . HIS A 1 434 ? 50.368 66.235 -15.767 1.00 6.69 ? 434 HIS A CG 1 ATOM 3495 N ND1 . HIS A 1 434 ? 50.748 65.109 -16.466 1.00 7.95 ? 434 HIS A ND1 1 ATOM 3496 C CD2 . HIS A 1 434 ? 51.204 67.231 -16.146 1.00 8.05 ? 434 HIS A CD2 1 ATOM 3497 C CE1 . HIS A 1 434 ? 51.746 65.432 -17.283 1.00 8.71 ? 434 HIS A CE1 1 ATOM 3498 N NE2 . HIS A 1 434 ? 52.037 66.711 -17.116 1.00 9.13 ? 434 HIS A NE2 1 ATOM 3499 N N A TYR A 1 435 ? 51.408 67.172 -12.466 0.50 6.76 ? 435 TYR A N 1 ATOM 3500 N N B TYR A 1 435 ? 51.427 67.170 -12.478 0.50 5.63 ? 435 TYR A N 1 ATOM 3501 C CA A TYR A 1 435 ? 52.693 67.748 -12.094 0.50 7.06 ? 435 TYR A CA 1 ATOM 3502 C CA B TYR A 1 435 ? 52.750 67.687 -12.161 0.50 4.76 ? 435 TYR A CA 1 ATOM 3503 C C A TYR A 1 435 ? 53.463 66.819 -11.163 0.50 7.23 ? 435 TYR A C 1 ATOM 3504 C C B TYR A 1 435 ? 53.502 66.857 -11.113 0.50 5.78 ? 435 TYR A C 1 ATOM 3505 O O A TYR A 1 435 ? 54.666 66.618 -11.330 0.50 7.25 ? 435 TYR A O 1 ATOM 3506 O O B TYR A 1 435 ? 54.714 66.727 -11.177 0.50 5.52 ? 435 TYR A O 1 ATOM 3507 C CB A TYR A 1 435 ? 52.496 69.112 -11.428 0.50 8.59 ? 435 TYR A CB 1 ATOM 3508 C CB B TYR A 1 435 ? 52.698 69.176 -11.832 0.50 5.19 ? 435 TYR A CB 1 ATOM 3509 C CG A TYR A 1 435 ? 52.394 70.261 -12.405 0.50 10.80 ? 435 TYR A CG 1 ATOM 3510 C CG B TYR A 1 435 ? 52.571 70.029 -13.088 0.50 3.83 ? 435 TYR A CG 1 ATOM 3511 C CD1 A TYR A 1 435 ? 51.514 70.210 -13.478 0.50 10.43 ? 435 TYR A CD1 1 ATOM 3512 C CD1 B TYR A 1 435 ? 53.531 69.984 -14.100 0.50 6.01 ? 435 TYR A CD1 1 ATOM 3513 C CD2 A TYR A 1 435 ? 53.177 71.398 -12.255 0.50 12.81 ? 435 TYR A CD2 1 ATOM 3514 C CD2 B TYR A 1 435 ? 51.462 70.817 -13.296 0.50 4.13 ? 435 TYR A CD2 1 ATOM 3515 C CE1 A TYR A 1 435 ? 51.417 71.258 -14.374 0.50 11.93 ? 435 TYR A CE1 1 ATOM 3516 C CE1 B TYR A 1 435 ? 53.397 70.766 -15.260 0.50 8.46 ? 435 TYR A CE1 1 ATOM 3517 C CE2 A TYR A 1 435 ? 53.087 72.451 -13.145 0.50 14.73 ? 435 TYR A CE2 1 ATOM 3518 C CE2 B TYR A 1 435 ? 51.326 71.598 -14.430 0.50 6.33 ? 435 TYR A CE2 1 ATOM 3519 C CZ A TYR A 1 435 ? 52.205 72.376 -14.202 0.50 12.98 ? 435 TYR A CZ 1 ATOM 3520 C CZ B TYR A 1 435 ? 52.293 71.574 -15.413 0.50 6.54 ? 435 TYR A CZ 1 ATOM 3521 O OH A TYR A 1 435 ? 52.112 73.422 -15.091 0.50 16.38 ? 435 TYR A OH 1 ATOM 3522 O OH B TYR A 1 435 ? 52.166 72.341 -16.564 0.50 7.86 ? 435 TYR A OH 1 ATOM 3523 N N . VAL A 1 436 ? 52.765 66.253 -10.184 1.00 5.92 ? 436 VAL A N 1 ATOM 3524 C CA . VAL A 1 436 ? 53.399 65.318 -9.233 1.00 6.51 ? 436 VAL A CA 1 ATOM 3525 C C . VAL A 1 436 ? 53.934 64.118 -10.031 1.00 6.71 ? 436 VAL A C 1 ATOM 3526 O O . VAL A 1 436 ? 55.093 63.690 -9.850 1.00 6.48 ? 436 VAL A O 1 ATOM 3527 C CB . VAL A 1 436 ? 52.422 64.897 -8.124 1.00 6.31 ? 436 VAL A CB 1 ATOM 3528 C CG1 . VAL A 1 436 ? 52.961 63.685 -7.339 1.00 7.53 ? 436 VAL A CG1 1 ATOM 3529 C CG2 . VAL A 1 436 ? 52.224 66.061 -7.173 1.00 7.28 ? 436 VAL A CG2 1 ATOM 3530 N N . ARG A 1 437 ? 53.111 63.525 -10.888 1.00 5.84 ? 437 ARG A N 1 ATOM 3531 C CA . ARG A 1 437 ? 53.578 62.381 -11.682 1.00 6.58 ? 437 ARG A CA 1 ATOM 3532 C C . ARG A 1 437 ? 54.819 62.764 -12.495 1.00 7.10 ? 437 ARG A C 1 ATOM 3533 O O . ARG A 1 437 ? 55.817 62.013 -12.542 1.00 6.79 ? 437 ARG A O 1 ATOM 3534 C CB . ARG A 1 437 ? 52.482 61.924 -12.626 1.00 6.96 ? 437 ARG A CB 1 ATOM 3535 C CG . ARG A 1 437 ? 52.957 60.918 -13.661 1.00 8.32 ? 437 ARG A CG 1 ATOM 3536 C CD . ARG A 1 437 ? 51.829 60.442 -14.534 1.00 8.32 ? 437 ARG A CD 1 ATOM 3537 N NE . ARG A 1 437 ? 52.355 59.701 -15.693 1.00 8.00 ? 437 ARG A NE 1 ATOM 3538 C CZ . ARG A 1 437 ? 51.621 58.898 -16.442 1.00 8.38 ? 437 ARG A CZ 1 ATOM 3539 N NH1 . ARG A 1 437 ? 50.360 58.636 -16.128 1.00 9.11 ? 437 ARG A NH1 1 ATOM 3540 N NH2 . ARG A 1 437 ? 52.172 58.345 -17.511 1.00 8.69 ? 437 ARG A NH2 1 ATOM 3541 N N . ALA A 1 438 ? 54.767 63.919 -13.176 1.00 6.19 ? 438 ALA A N 1 ATOM 3542 C CA . ALA A 1 438 ? 55.862 64.310 -14.068 1.00 6.69 ? 438 ALA A CA 1 ATOM 3543 C C . ALA A 1 438 ? 57.124 64.606 -13.250 1.00 6.80 ? 438 ALA A C 1 ATOM 3544 O O . ALA A 1 438 ? 58.225 64.257 -13.699 1.00 7.56 ? 438 ALA A O 1 ATOM 3545 C CB . ALA A 1 438 ? 55.443 65.494 -14.887 1.00 7.72 ? 438 ALA A CB 1 ATOM 3546 N N . ALA A 1 439 ? 57.000 65.240 -12.085 1.00 7.50 ? 439 ALA A N 1 ATOM 3547 C CA . ALA A 1 439 ? 58.173 65.564 -11.273 1.00 6.79 ? 439 ALA A CA 1 ATOM 3548 C C . ALA A 1 439 ? 58.796 64.277 -10.742 1.00 7.04 ? 439 ALA A C 1 ATOM 3549 O O . ALA A 1 439 ? 60.047 64.137 -10.729 1.00 7.62 ? 439 ALA A O 1 ATOM 3550 C CB . ALA A 1 439 ? 57.807 66.491 -10.150 1.00 7.46 ? 439 ALA A CB 1 ATOM 3551 N N . GLU A 1 440 ? 57.985 63.344 -10.264 1.00 6.62 ? 440 GLU A N 1 ATOM 3552 C CA . GLU A 1 440 ? 58.533 62.109 -9.755 1.00 6.95 ? 440 GLU A CA 1 ATOM 3553 C C . GLU A 1 440 ? 59.202 61.306 -10.866 1.00 7.23 ? 440 GLU A C 1 ATOM 3554 O O . GLU A 1 440 ? 60.259 60.680 -10.662 1.00 7.94 ? 440 GLU A O 1 ATOM 3555 C CB . GLU A 1 440 ? 57.450 61.261 -9.054 1.00 7.26 ? 440 GLU A CB 1 ATOM 3556 C CG . GLU A 1 440 ? 56.910 61.907 -7.790 1.00 8.33 ? 440 GLU A CG 1 ATOM 3557 C CD . GLU A 1 440 ? 56.243 60.923 -6.845 1.00 11.42 ? 440 GLU A CD 1 ATOM 3558 O OE1 . GLU A 1 440 ? 55.136 60.442 -7.123 1.00 11.28 ? 440 GLU A OE1 1 ATOM 3559 O OE2 . GLU A 1 440 ? 56.861 60.573 -5.822 1.00 11.41 ? 440 GLU A OE2 1 ATOM 3560 N N . MET A 1 441 ? 58.580 61.275 -12.038 1.00 6.10 ? 441 MET A N 1 ATOM 3561 C CA . MET A 1 441 ? 59.130 60.518 -13.145 1.00 6.99 ? 441 MET A CA 1 ATOM 3562 C C . MET A 1 441 ? 60.430 61.138 -13.690 1.00 7.38 ? 441 MET A C 1 ATOM 3563 O O . MET A 1 441 ? 61.459 60.437 -13.822 1.00 7.94 ? 441 MET A O 1 ATOM 3564 C CB . MET A 1 441 ? 58.090 60.376 -14.267 1.00 7.17 ? 441 MET A CB 1 ATOM 3565 C CG . MET A 1 441 ? 58.600 59.647 -15.498 1.00 7.31 ? 441 MET A CG 1 ATOM 3566 S SD . MET A 1 441 ? 57.348 59.405 -16.772 1.00 8.40 ? 441 MET A SD 1 ATOM 3567 C CE . MET A 1 441 ? 56.240 58.226 -15.961 1.00 10.43 ? 441 MET A CE 1 ATOM 3568 N N . LEU A 1 442 ? 60.428 62.444 -13.959 1.00 6.99 ? 442 LEU A N 1 ATOM 3569 C CA . LEU A 1 442 ? 61.614 63.102 -14.514 1.00 7.80 ? 442 LEU A CA 1 ATOM 3570 C C . LEU A 1 442 ? 62.798 62.969 -13.583 1.00 8.25 ? 442 LEU A C 1 ATOM 3571 O O . LEU A 1 442 ? 63.952 62.808 -14.055 1.00 9.42 ? 442 LEU A O 1 ATOM 3572 C CB . LEU A 1 442 ? 61.326 64.575 -14.792 1.00 7.76 ? 442 LEU A CB 1 ATOM 3573 C CG . LEU A 1 442 ? 60.715 64.829 -16.155 1.00 7.64 ? 442 LEU A CG 1 ATOM 3574 C CD1 . LEU A 1 442 ? 60.111 66.204 -16.180 1.00 9.90 ? 442 LEU A CD1 1 ATOM 3575 C CD2 . LEU A 1 442 ? 61.827 64.693 -17.212 1.00 9.47 ? 442 LEU A CD2 1 ATOM 3576 N N . SER A 1 443 ? 62.569 63.072 -12.270 1.00 7.79 ? 443 SER A N 1 ATOM 3577 C CA . SER A 1 443 ? 63.689 63.021 -11.327 1.00 8.57 ? 443 SER A CA 1 ATOM 3578 C C . SER A 1 443 ? 64.086 61.604 -10.985 1.00 8.90 ? 443 SER A C 1 ATOM 3579 O O . SER A 1 443 ? 65.200 61.406 -10.446 1.00 9.92 ? 443 SER A O 1 ATOM 3580 C CB . SER A 1 443 ? 63.418 63.829 -10.081 1.00 8.48 ? 443 SER A CB 1 ATOM 3581 O OG . SER A 1 443 ? 62.339 63.286 -9.320 1.00 7.96 ? 443 SER A OG 1 ATOM 3582 N N . ALA A 1 444 ? 63.276 60.612 -11.316 1.00 7.46 ? 444 ALA A N 1 ATOM 3583 C CA . ALA A 1 444 ? 63.573 59.201 -11.003 1.00 8.86 ? 444 ALA A CA 1 ATOM 3584 C C . ALA A 1 444 ? 64.752 58.665 -11.777 1.00 9.40 ? 444 ALA A C 1 ATOM 3585 O O . ALA A 1 444 ? 65.374 57.662 -11.357 1.00 10.52 ? 444 ALA A O 1 ATOM 3586 C CB . ALA A 1 444 ? 62.379 58.304 -11.266 1.00 8.54 ? 444 ALA A CB 1 ATOM 3587 N N . TRP A 1 445 ? 65.020 59.241 -12.944 1.00 10.06 ? 445 TRP A N 1 ATOM 3588 C CA . TRP A 1 445 ? 66.062 58.713 -13.825 1.00 10.67 ? 445 TRP A CA 1 ATOM 3589 C C . TRP A 1 445 ? 67.458 58.783 -13.187 1.00 11.30 ? 445 TRP A C 1 ATOM 3590 O O . TRP A 1 445 ? 68.324 57.983 -13.578 1.00 12.92 ? 445 TRP A O 1 ATOM 3591 C CB . TRP A 1 445 ? 66.075 59.446 -15.164 1.00 10.38 ? 445 TRP A CB 1 ATOM 3592 C CG . TRP A 1 445 ? 64.801 59.274 -15.915 1.00 8.96 ? 445 TRP A CG 1 ATOM 3593 C CD1 . TRP A 1 445 ? 63.790 60.212 -16.039 1.00 9.58 ? 445 TRP A CD1 1 ATOM 3594 C CD2 . TRP A 1 445 ? 64.343 58.101 -16.585 1.00 9.27 ? 445 TRP A CD2 1 ATOM 3595 N NE1 . TRP A 1 445 ? 62.764 59.689 -16.787 1.00 9.38 ? 445 TRP A NE1 1 ATOM 3596 C CE2 . TRP A 1 445 ? 63.063 58.399 -17.130 1.00 8.61 ? 445 TRP A CE2 1 ATOM 3597 C CE3 . TRP A 1 445 ? 64.894 56.822 -16.817 1.00 10.54 ? 445 TRP A CE3 1 ATOM 3598 C CZ2 . TRP A 1 445 ? 62.349 57.487 -17.875 1.00 9.05 ? 445 TRP A CZ2 1 ATOM 3599 C CZ3 . TRP A 1 445 ? 64.165 55.922 -17.567 1.00 10.36 ? 445 TRP A CZ3 1 ATOM 3600 C CH2 . TRP A 1 445 ? 62.898 56.245 -18.072 1.00 10.28 ? 445 TRP A CH2 1 ATOM 3601 N N . HIS A 1 446 ? 67.689 59.724 -12.279 1.00 11.14 ? 446 HIS A N 1 ATOM 3602 C CA . HIS A 1 446 ? 68.980 59.837 -11.625 1.00 12.86 ? 446 HIS A CA 1 ATOM 3603 C C . HIS A 1 446 ? 68.826 59.727 -10.121 1.00 12.14 ? 446 HIS A C 1 ATOM 3604 O O . HIS A 1 446 ? 67.764 59.965 -9.551 1.00 11.50 ? 446 HIS A O 1 ATOM 3605 C CB . HIS A 1 446 ? 69.576 61.206 -11.872 1.00 13.39 ? 446 HIS A CB 1 ATOM 3606 C CG . HIS A 1 446 ? 69.964 61.460 -13.285 1.00 15.52 ? 446 HIS A CG 1 ATOM 3607 N ND1 . HIS A 1 446 ? 69.195 62.212 -14.150 1.00 17.79 ? 446 HIS A ND1 1 ATOM 3608 C CD2 . HIS A 1 446 ? 71.077 61.110 -13.977 1.00 20.40 ? 446 HIS A CD2 1 ATOM 3609 C CE1 . HIS A 1 446 ? 69.798 62.291 -15.320 1.00 21.47 ? 446 HIS A CE1 1 ATOM 3610 N NE2 . HIS A 1 446 ? 70.941 61.638 -15.243 1.00 20.01 ? 446 HIS A NE2 1 ATOM 3611 N N . SER A 1 447 ? 69.951 59.406 -9.485 1.00 12.93 ? 447 SER A N 1 ATOM 3612 C CA A SER A 1 447 ? 70.164 59.614 -8.076 0.50 12.62 ? 447 SER A CA 1 ATOM 3613 C CA B SER A 1 447 ? 70.146 59.637 -8.056 0.50 13.07 ? 447 SER A CA 1 ATOM 3614 C C . SER A 1 447 ? 70.598 61.072 -7.852 1.00 13.07 ? 447 SER A C 1 ATOM 3615 O O . SER A 1 447 ? 71.407 61.606 -8.639 1.00 14.70 ? 447 SER A O 1 ATOM 3616 C CB A SER A 1 447 ? 71.261 58.656 -7.633 0.50 14.34 ? 447 SER A CB 1 ATOM 3617 C CB B SER A 1 447 ? 71.199 58.686 -7.479 0.50 14.87 ? 447 SER A CB 1 ATOM 3618 O OG A SER A 1 447 ? 71.225 58.526 -6.241 0.50 12.74 ? 447 SER A OG 1 ATOM 3619 O OG B SER A 1 447 ? 70.605 57.499 -7.001 0.50 15.64 ? 447 SER A OG 1 ATOM 3620 N N . TRP A 1 448 ? 70.078 61.743 -6.831 1.00 10.96 ? 448 TRP A N 1 ATOM 3621 C CA . TRP A 1 448 ? 70.405 63.127 -6.591 1.00 12.66 ? 448 TRP A CA 1 ATOM 3622 C C . TRP A 1 448 ? 71.105 63.307 -5.275 1.00 14.30 ? 448 TRP A C 1 ATOM 3623 O O . TRP A 1 448 ? 70.731 62.709 -4.285 1.00 15.04 ? 448 TRP A O 1 ATOM 3624 C CB . TRP A 1 448 ? 69.133 63.997 -6.593 1.00 11.72 ? 448 TRP A CB 1 ATOM 3625 C CG . TRP A 1 448 ? 68.477 64.025 -7.960 1.00 10.40 ? 448 TRP A CG 1 ATOM 3626 C CD1 . TRP A 1 448 ? 67.636 63.084 -8.481 1.00 11.30 ? 448 TRP A CD1 1 ATOM 3627 C CD2 . TRP A 1 448 ? 68.640 65.021 -8.966 1.00 10.42 ? 448 TRP A CD2 1 ATOM 3628 N NE1 . TRP A 1 448 ? 67.233 63.449 -9.744 1.00 10.82 ? 448 TRP A NE1 1 ATOM 3629 C CE2 . TRP A 1 448 ? 67.848 64.628 -10.070 1.00 9.89 ? 448 TRP A CE2 1 ATOM 3630 C CE3 . TRP A 1 448 ? 69.379 66.212 -9.046 1.00 11.73 ? 448 TRP A CE3 1 ATOM 3631 C CZ2 . TRP A 1 448 ? 67.755 65.382 -11.224 1.00 11.54 ? 448 TRP A CZ2 1 ATOM 3632 C CZ3 . TRP A 1 448 ? 69.282 66.973 -10.211 1.00 11.30 ? 448 TRP A CZ3 1 ATOM 3633 C CH2 . TRP A 1 448 ? 68.481 66.523 -11.292 1.00 10.93 ? 448 TRP A CH2 1 ATOM 3634 N N . ASP A 1 449 ? 72.100 64.191 -5.262 1.00 16.66 ? 449 ASP A N 1 ATOM 3635 C CA . ASP A 1 449 ? 72.716 64.636 -4.016 1.00 18.02 ? 449 ASP A CA 1 ATOM 3636 C C . ASP A 1 449 ? 71.692 65.238 -3.074 1.00 17.69 ? 449 ASP A C 1 ATOM 3637 O O . ASP A 1 449 ? 70.787 65.932 -3.526 1.00 16.78 ? 449 ASP A O 1 ATOM 3638 C CB . ASP A 1 449 ? 73.764 65.706 -4.299 1.00 19.94 ? 449 ASP A CB 1 ATOM 3639 C CG . ASP A 1 449 ? 74.608 66.004 -3.090 1.00 22.38 ? 449 ASP A CG 1 ATOM 3640 O OD1 . ASP A 1 449 ? 75.499 65.179 -2.780 1.00 31.09 ? 449 ASP A OD1 1 ATOM 3641 O OD2 . ASP A 1 449 ? 74.443 67.002 -2.374 1.00 26.48 ? 449 ASP A OD2 1 ATOM 3642 N N . GLY A 1 450 ? 71.848 65.023 -1.768 1.00 17.88 ? 450 GLY A N 1 ATOM 3643 C CA . GLY A 1 450 ? 70.982 65.661 -0.794 1.00 18.30 ? 450 GLY A CA 1 ATOM 3644 C C . GLY A 1 450 ? 70.837 67.164 -0.937 1.00 18.94 ? 450 GLY A C 1 ATOM 3645 O O . GLY A 1 450 ? 69.775 67.731 -0.644 1.00 19.26 ? 450 GLY A O 1 ATOM 3646 N N . MET A 1 451 ? 71.904 67.831 -1.388 1.00 18.40 ? 451 MET A N 1 ATOM 3647 C CA . MET A 1 451 ? 71.885 69.272 -1.532 1.00 19.30 ? 451 MET A CA 1 ATOM 3648 C C . MET A 1 451 ? 70.902 69.746 -2.593 1.00 17.15 ? 451 MET A C 1 ATOM 3649 O O . MET A 1 451 ? 70.523 70.916 -2.600 1.00 18.22 ? 451 MET A O 1 ATOM 3650 C CB . MET A 1 451 ? 73.289 69.795 -1.881 1.00 20.88 ? 451 MET A CB 1 ATOM 3651 C CG . MET A 1 451 ? 74.298 69.712 -0.735 1.00 26.34 ? 451 MET A CG 1 ATOM 3652 S SD . MET A 1 451 ? 73.712 70.519 0.780 1.00 38.37 ? 451 MET A SD 1 ATOM 3653 C CE . MET A 1 451 ? 73.582 72.262 0.215 1.00 37.37 ? 451 MET A CE 1 ATOM 3654 N N . ALA A 1 452 ? 70.492 68.839 -3.487 1.00 15.54 ? 452 ALA A N 1 ATOM 3655 C CA . ALA A 1 452 ? 69.555 69.195 -4.553 1.00 15.11 ? 452 ALA A CA 1 ATOM 3656 C C . ALA A 1 452 ? 68.122 69.325 -4.013 1.00 14.15 ? 452 ALA A C 1 ATOM 3657 O O . ALA A 1 452 ? 67.272 69.906 -4.699 1.00 14.95 ? 452 ALA A O 1 ATOM 3658 C CB . ALA A 1 452 ? 69.613 68.183 -5.690 1.00 14.94 ? 452 ALA A CB 1 ATOM 3659 N N . ARG A 1 453 ? 67.859 68.793 -2.813 1.00 13.40 ? 453 ARG A N 1 ATOM 3660 C CA . ARG A 1 453 ? 66.535 68.950 -2.157 1.00 14.13 ? 453 ARG A CA 1 ATOM 3661 C C . ARG A 1 453 ? 65.423 68.331 -3.013 1.00 13.13 ? 453 ARG A C 1 ATOM 3662 O O . ARG A 1 453 ? 64.274 68.809 -2.947 1.00 14.41 ? 453 ARG A O 1 ATOM 3663 C CB . ARG A 1 453 ? 66.249 70.422 -1.853 1.00 13.68 ? 453 ARG A CB 1 ATOM 3664 C CG . ARG A 1 453 ? 67.289 71.056 -0.917 1.00 15.79 ? 453 ARG A CG 1 ATOM 3665 C CD . ARG A 1 453 ? 67.075 72.552 -0.713 1.00 17.99 ? 453 ARG A CD 1 ATOM 3666 N NE . ARG A 1 453 ? 65.886 72.808 0.097 1.00 21.58 ? 453 ARG A NE 1 ATOM 3667 C CZ . ARG A 1 453 ? 65.382 74.014 0.315 1.00 23.37 ? 453 ARG A CZ 1 ATOM 3668 N NH1 . ARG A 1 453 ? 65.951 75.101 -0.226 1.00 24.90 ? 453 ARG A NH1 1 ATOM 3669 N NH2 . ARG A 1 453 ? 64.293 74.133 1.058 1.00 25.62 ? 453 ARG A NH2 1 ATOM 3670 N N . ILE A 1 454 ? 65.743 67.305 -3.795 1.00 11.57 ? 454 ILE A N 1 ATOM 3671 C CA . ILE A 1 454 ? 64.723 66.702 -4.662 1.00 11.20 ? 454 ILE A CA 1 ATOM 3672 C C . ILE A 1 454 ? 63.710 65.947 -3.796 1.00 11.22 ? 454 ILE A C 1 ATOM 3673 O O . ILE A 1 454 ? 62.497 66.169 -3.935 1.00 10.47 ? 454 ILE A O 1 ATOM 3674 C CB . ILE A 1 454 ? 65.388 65.748 -5.655 1.00 10.83 ? 454 ILE A CB 1 ATOM 3675 C CG1 . ILE A 1 454 ? 66.324 66.518 -6.608 1.00 13.28 ? 454 ILE A CG1 1 ATOM 3676 C CG2 . ILE A 1 454 ? 64.351 64.924 -6.436 1.00 11.43 ? 454 ILE A CG2 1 ATOM 3677 C CD1 . ILE A 1 454 ? 65.682 67.585 -7.477 1.00 14.18 ? 454 ILE A CD1 1 ATOM 3678 N N . GLU A 1 455 ? 64.165 65.078 -2.906 1.00 10.81 ? 455 GLU A N 1 ATOM 3679 C CA . GLU A 1 455 ? 63.242 64.296 -2.073 1.00 11.32 ? 455 GLU A CA 1 ATOM 3680 C C . GLU A 1 455 ? 62.410 65.219 -1.211 1.00 11.87 ? 455 GLU A C 1 ATOM 3681 O O . GLU A 1 455 ? 61.214 64.973 -1.028 1.00 11.26 ? 455 GLU A O 1 ATOM 3682 C CB . GLU A 1 455 ? 64.021 63.325 -1.176 1.00 13.24 ? 455 GLU A CB 1 ATOM 3683 C CG . GLU A 1 455 ? 64.626 62.134 -1.916 1.00 13.86 ? 455 GLU A CG 1 ATOM 3684 C CD . GLU A 1 455 ? 66.019 62.405 -2.534 1.00 13.62 ? 455 GLU A CD 1 ATOM 3685 O OE1 . GLU A 1 455 ? 66.508 63.563 -2.416 1.00 15.16 ? 455 GLU A OE1 1 ATOM 3686 O OE2 . GLU A 1 455 ? 66.563 61.451 -3.102 1.00 14.12 ? 455 GLU A OE2 1 ATOM 3687 N N . GLU A 1 456 ? 62.990 66.280 -0.694 1.00 12.30 ? 456 GLU A N 1 ATOM 3688 C CA . GLU A 1 456 ? 62.279 67.232 0.122 1.00 11.91 ? 456 GLU A CA 1 ATOM 3689 C C . GLU A 1 456 ? 61.106 67.862 -0.655 1.00 11.09 ? 456 GLU A C 1 ATOM 3690 O O . GLU A 1 456 ? 59.970 67.931 -0.160 1.00 10.57 ? 456 GLU A O 1 ATOM 3691 C CB . GLU A 1 456 ? 63.257 68.329 0.593 1.00 13.30 ? 456 GLU A CB 1 ATOM 3692 C CG . GLU A 1 456 ? 62.619 69.455 1.370 1.00 16.04 ? 456 GLU A CG 1 ATOM 3693 C CD . GLU A 1 456 ? 63.560 70.636 1.602 1.00 17.48 ? 456 GLU A CD 1 ATOM 3694 O OE1 . GLU A 1 456 ? 64.789 70.496 1.421 1.00 22.39 ? 456 GLU A OE1 1 ATOM 3695 O OE2 . GLU A 1 456 ? 63.064 71.722 1.970 1.00 21.94 ? 456 GLU A OE2 1 ATOM 3696 N N . ARG A 1 457 ? 61.389 68.380 -1.841 1.00 9.91 ? 457 ARG A N 1 ATOM 3697 C CA . ARG A 1 457 ? 60.349 69.024 -2.667 1.00 9.72 ? 457 ARG A CA 1 ATOM 3698 C C . ARG A 1 457 ? 59.269 68.032 -3.094 1.00 8.81 ? 457 ARG A C 1 ATOM 3699 O O . ARG A 1 457 ? 58.078 68.364 -3.056 1.00 8.82 ? 457 ARG A O 1 ATOM 3700 C CB . ARG A 1 457 ? 60.986 69.763 -3.864 1.00 10.09 ? 457 ARG A CB 1 ATOM 3701 C CG . ARG A 1 457 ? 61.305 71.223 -3.624 1.00 13.56 ? 457 ARG A CG 1 ATOM 3702 C CD . ARG A 1 457 ? 62.287 71.465 -2.496 1.00 14.50 ? 457 ARG A CD 1 ATOM 3703 N NE . ARG A 1 457 ? 62.496 72.893 -2.198 1.00 16.23 ? 457 ARG A NE 1 ATOM 3704 C CZ . ARG A 1 457 ? 63.392 73.667 -2.806 1.00 20.48 ? 457 ARG A CZ 1 ATOM 3705 N NH1 . ARG A 1 457 ? 64.178 73.186 -3.780 1.00 18.58 ? 457 ARG A NH1 1 ATOM 3706 N NH2 . ARG A 1 457 ? 63.489 74.940 -2.442 1.00 22.51 ? 457 ARG A NH2 1 ATOM 3707 N N . LEU A 1 458 ? 59.655 66.815 -3.413 1.00 7.78 ? 458 LEU A N 1 ATOM 3708 C CA . LEU A 1 458 ? 58.655 65.823 -3.864 1.00 8.35 ? 458 LEU A CA 1 ATOM 3709 C C . LEU A 1 458 ? 57.789 65.373 -2.704 1.00 9.04 ? 458 LEU A C 1 ATOM 3710 O O . LEU A 1 458 ? 56.568 65.167 -2.875 1.00 9.21 ? 458 LEU A O 1 ATOM 3711 C CB . LEU A 1 458 ? 59.380 64.630 -4.459 1.00 8.72 ? 458 LEU A CB 1 ATOM 3712 C CG . LEU A 1 458 ? 60.033 64.923 -5.823 1.00 8.55 ? 458 LEU A CG 1 ATOM 3713 C CD1 . LEU A 1 458 ? 60.791 63.702 -6.231 1.00 11.19 ? 458 LEU A CD1 1 ATOM 3714 C CD2 . LEU A 1 458 ? 58.979 65.309 -6.890 1.00 9.99 ? 458 LEU A CD2 1 ATOM 3715 N N . GLU A 1 459 ? 58.370 65.261 -1.504 1.00 8.71 ? 459 GLU A N 1 ATOM 3716 C CA . GLU A 1 459 ? 57.545 64.870 -0.346 1.00 9.49 ? 459 GLU A CA 1 ATOM 3717 C C . GLU A 1 459 ? 56.539 65.965 -0.043 1.00 9.45 ? 459 GLU A C 1 ATOM 3718 O O . GLU A 1 459 ? 55.353 65.698 0.235 1.00 9.06 ? 459 GLU A O 1 ATOM 3719 C CB . GLU A 1 459 ? 58.438 64.638 0.860 1.00 10.14 ? 459 GLU A CB 1 ATOM 3720 C CG . GLU A 1 459 ? 57.661 64.263 2.111 1.00 12.56 ? 459 GLU A CG 1 ATOM 3721 C CD . GLU A 1 459 ? 58.561 63.628 3.172 1.00 17.35 ? 459 GLU A CD 1 ATOM 3722 O OE1 . GLU A 1 459 ? 59.212 64.401 3.894 1.00 22.08 ? 459 GLU A OE1 1 ATOM 3723 O OE2 . GLU A 1 459 ? 58.633 62.381 3.266 1.00 19.63 ? 459 GLU A OE2 1 ATOM 3724 N N . GLN A 1 460 ? 56.951 67.218 -0.117 1.00 8.75 ? 460 GLN A N 1 ATOM 3725 C CA . GLN A 1 460 ? 56.020 68.345 0.101 1.00 10.56 ? 460 GLN A CA 1 ATOM 3726 C C . GLN A 1 460 ? 54.880 68.267 -0.936 1.00 9.38 ? 460 GLN A C 1 ATOM 3727 O O . GLN A 1 460 ? 53.687 68.361 -0.594 1.00 9.45 ? 460 GLN A O 1 ATOM 3728 C CB . GLN A 1 460 ? 56.751 69.691 -0.025 1.00 11.85 ? 460 GLN A CB 1 ATOM 3729 C CG . GLN A 1 460 ? 55.864 70.932 0.020 1.00 16.92 ? 460 GLN A CG 1 ATOM 3730 C CD . GLN A 1 460 ? 56.661 72.215 -0.258 1.00 16.79 ? 460 GLN A CD 1 ATOM 3731 O OE1 . GLN A 1 460 ? 57.731 72.164 -0.879 1.00 25.27 ? 460 GLN A OE1 1 ATOM 3732 N NE2 . GLN A 1 460 ? 56.117 73.343 0.141 1.00 24.45 ? 460 GLN A NE2 1 ATOM 3733 N N . ALA A 1 461 ? 55.234 68.098 -2.208 1.00 7.96 ? 461 ALA A N 1 ATOM 3734 C CA . ALA A 1 461 ? 54.209 68.084 -3.247 1.00 8.03 ? 461 ALA A CA 1 ATOM 3735 C C . ALA A 1 461 ? 53.254 66.903 -3.061 1.00 7.97 ? 461 ALA A C 1 ATOM 3736 O O . ALA A 1 461 ? 52.031 67.076 -3.157 1.00 8.29 ? 461 ALA A O 1 ATOM 3737 C CB . ALA A 1 461 ? 54.880 68.043 -4.613 1.00 8.82 ? 461 ALA A CB 1 ATOM 3738 N N . ARG A 1 462 ? 53.776 65.726 -2.765 1.00 7.62 ? 462 ARG A N 1 ATOM 3739 C CA . ARG A 1 462 ? 52.904 64.572 -2.570 1.00 7.15 ? 462 ARG A CA 1 ATOM 3740 C C . ARG A 1 462 ? 51.966 64.809 -1.390 1.00 7.37 ? 462 ARG A C 1 ATOM 3741 O O . ARG A 1 462 ? 50.775 64.423 -1.425 1.00 7.72 ? 462 ARG A O 1 ATOM 3742 C CB . ARG A 1 462 ? 53.665 63.285 -2.305 1.00 7.65 ? 462 ARG A CB 1 ATOM 3743 C CG . ARG A 1 462 ? 54.392 62.692 -3.519 1.00 7.70 ? 462 ARG A CG 1 ATOM 3744 C CD . ARG A 1 462 ? 54.885 61.278 -3.269 1.00 8.54 ? 462 ARG A CD 1 ATOM 3745 N NE . ARG A 1 462 ? 55.791 61.230 -2.109 1.00 9.10 ? 462 ARG A NE 1 ATOM 3746 C CZ . ARG A 1 462 ? 57.104 61.405 -2.183 1.00 10.14 ? 462 ARG A CZ 1 ATOM 3747 N NH1 . ARG A 1 462 ? 57.713 61.541 -3.356 1.00 11.41 ? 462 ARG A NH1 1 ATOM 3748 N NH2 . ARG A 1 462 ? 57.842 61.395 -1.076 1.00 12.48 ? 462 ARG A NH2 1 ATOM 3749 N N . ARG A 1 463 ? 52.482 65.425 -0.326 1.00 7.39 ? 463 ARG A N 1 ATOM 3750 C CA . ARG A 1 463 ? 51.670 65.562 0.877 1.00 6.94 ? 463 ARG A CA 1 ATOM 3751 C C . ARG A 1 463 ? 50.603 66.634 0.714 1.00 7.54 ? 463 ARG A C 1 ATOM 3752 O O . ARG A 1 463 ? 49.502 66.463 1.274 1.00 8.26 ? 463 ARG A O 1 ATOM 3753 C CB . ARG A 1 463 ? 52.552 65.852 2.107 1.00 7.33 ? 463 ARG A CB 1 ATOM 3754 C CG . ARG A 1 463 ? 53.278 64.628 2.521 1.00 8.45 ? 463 ARG A CG 1 ATOM 3755 C CD . ARG A 1 463 ? 54.307 64.809 3.639 1.00 10.40 ? 463 ARG A CD 1 ATOM 3756 N NE . ARG A 1 463 ? 54.797 63.479 3.971 1.00 11.76 ? 463 ARG A NE 1 ATOM 3757 C CZ . ARG A 1 463 ? 55.537 63.179 5.041 1.00 15.11 ? 463 ARG A CZ 1 ATOM 3758 N NH1 . ARG A 1 463 ? 55.933 64.140 5.839 1.00 15.31 ? 463 ARG A NH1 1 ATOM 3759 N NH2 . ARG A 1 463 ? 55.906 61.925 5.257 1.00 15.03 ? 463 ARG A NH2 1 ATOM 3760 N N . GLU A 1 464 ? 50.860 67.720 -0.006 1.00 7.43 ? 464 GLU A N 1 ATOM 3761 C CA . GLU A 1 464 ? 49.832 68.726 -0.180 1.00 8.14 ? 464 GLU A CA 1 ATOM 3762 C C . GLU A 1 464 ? 48.745 68.197 -1.106 1.00 8.49 ? 464 GLU A C 1 ATOM 3763 O O . GLU A 1 464 ? 47.564 68.455 -0.857 1.00 8.12 ? 464 GLU A O 1 ATOM 3764 C CB . GLU A 1 464 ? 50.385 70.028 -0.736 1.00 9.82 ? 464 GLU A CB 1 ATOM 3765 C CG . GLU A 1 464 ? 51.547 70.677 0.047 1.00 12.73 ? 464 GLU A CG 1 ATOM 3766 C CD . GLU A 1 464 ? 51.265 71.132 1.467 1.00 19.33 ? 464 GLU A CD 1 ATOM 3767 O OE1 . GLU A 1 464 ? 50.270 70.743 2.077 1.00 17.17 ? 464 GLU A OE1 1 ATOM 3768 O OE2 . GLU A 1 464 ? 52.121 71.905 1.974 1.00 22.11 ? 464 GLU A OE2 1 ATOM 3769 N N . LEU A 1 465 ? 49.110 67.475 -2.159 1.00 6.51 ? 465 LEU A N 1 ATOM 3770 C CA . LEU A 1 465 ? 48.073 66.909 -3.041 1.00 7.04 ? 465 LEU A CA 1 ATOM 3771 C C . LEU A 1 465 ? 47.294 65.836 -2.266 1.00 6.51 ? 465 LEU A C 1 ATOM 3772 O O . LEU A 1 465 ? 46.063 65.732 -2.374 1.00 6.90 ? 465 LEU A O 1 ATOM 3773 C CB . LEU A 1 465 ? 48.719 66.302 -4.291 1.00 7.40 ? 465 LEU A CB 1 ATOM 3774 C CG . LEU A 1 465 ? 47.726 65.651 -5.272 1.00 7.64 ? 465 LEU A CG 1 ATOM 3775 C CD1 . LEU A 1 465 ? 46.639 66.610 -5.760 1.00 8.38 ? 465 LEU A CD1 1 ATOM 3776 C CD2 . LEU A 1 465 ? 48.542 65.101 -6.430 1.00 8.55 ? 465 LEU A CD2 1 ATOM 3777 N N . SER A 1 466 ? 47.988 65.033 -1.481 1.00 6.22 ? 466 SER A N 1 ATOM 3778 C CA . SER A 1 466 ? 47.329 64.023 -0.666 1.00 6.07 ? 466 SER A CA 1 ATOM 3779 C C . SER A 1 466 ? 46.332 64.612 0.322 1.00 6.54 ? 466 SER A C 1 ATOM 3780 O O . SER A 1 466 ? 45.199 64.099 0.464 1.00 6.79 ? 466 SER A O 1 ATOM 3781 C CB . SER A 1 466 ? 48.355 63.161 0.082 1.00 6.40 ? 466 SER A CB 1 ATOM 3782 O OG . SER A 1 466 ? 49.089 62.343 -0.778 1.00 7.12 ? 466 SER A OG 1 ATOM 3783 N N . LEU A 1 467 ? 46.700 65.701 0.961 1.00 6.08 ? 467 LEU A N 1 ATOM 3784 C CA . LEU A 1 467 ? 45.836 66.348 1.926 1.00 6.83 ? 467 LEU A CA 1 ATOM 3785 C C . LEU A 1 467 ? 44.538 66.764 1.228 1.00 6.19 ? 467 LEU A C 1 ATOM 3786 O O . LEU A 1 467 ? 43.446 66.650 1.785 1.00 6.63 ? 467 LEU A O 1 ATOM 3787 C CB . LEU A 1 467 ? 46.568 67.567 2.508 1.00 7.85 ? 467 LEU A CB 1 ATOM 3788 C CG . LEU A 1 467 ? 45.805 68.210 3.654 1.00 10.67 ? 467 LEU A CG 1 ATOM 3789 C CD1 . LEU A 1 467 ? 45.968 67.337 4.933 1.00 15.54 ? 467 LEU A CD1 1 ATOM 3790 C CD2 . LEU A 1 467 ? 46.360 69.644 3.873 1.00 12.06 ? 467 LEU A CD2 1 ATOM 3791 N N . PHE A 1 468 ? 44.650 67.281 0.014 1.00 5.96 ? 468 PHE A N 1 ATOM 3792 C CA . PHE A 1 468 ? 43.464 67.803 -0.668 1.00 6.12 ? 468 PHE A CA 1 ATOM 3793 C C . PHE A 1 468 ? 42.486 66.704 -1.084 1.00 5.50 ? 468 PHE A C 1 ATOM 3794 O O . PHE A 1 468 ? 41.319 67.000 -1.397 1.00 6.43 ? 468 PHE A O 1 ATOM 3795 C CB . PHE A 1 468 ? 43.895 68.622 -1.890 1.00 6.79 ? 468 PHE A CB 1 ATOM 3796 C CG . PHE A 1 468 ? 42.783 69.450 -2.471 1.00 5.33 ? 468 PHE A CG 1 ATOM 3797 C CD1 . PHE A 1 468 ? 42.154 70.390 -1.703 1.00 7.24 ? 468 PHE A CD1 1 ATOM 3798 C CD2 . PHE A 1 468 ? 42.349 69.259 -3.804 1.00 6.73 ? 468 PHE A CD2 1 ATOM 3799 C CE1 . PHE A 1 468 ? 41.089 71.131 -2.215 1.00 7.36 ? 468 PHE A CE1 1 ATOM 3800 C CE2 . PHE A 1 468 ? 41.265 70.019 -4.309 1.00 5.78 ? 468 PHE A CE2 1 ATOM 3801 C CZ . PHE A 1 468 ? 40.662 70.941 -3.513 1.00 6.90 ? 468 PHE A CZ 1 ATOM 3802 N N . GLN A 1 469 ? 42.916 65.448 -1.076 1.00 5.13 ? 469 GLN A N 1 ATOM 3803 C CA . GLN A 1 469 ? 41.967 64.370 -1.328 1.00 5.23 ? 469 GLN A CA 1 ATOM 3804 C C . GLN A 1 469 ? 40.941 64.194 -0.212 1.00 5.95 ? 469 GLN A C 1 ATOM 3805 O O . GLN A 1 469 ? 39.981 63.431 -0.368 1.00 5.90 ? 469 GLN A O 1 ATOM 3806 C CB . GLN A 1 469 ? 42.686 63.034 -1.537 1.00 5.36 ? 469 GLN A CB 1 ATOM 3807 C CG . GLN A 1 469 ? 43.780 63.115 -2.618 1.00 5.79 ? 469 GLN A CG 1 ATOM 3808 C CD . GLN A 1 469 ? 43.275 63.734 -3.887 1.00 5.97 ? 469 GLN A CD 1 ATOM 3809 O OE1 . GLN A 1 469 ? 42.279 63.281 -4.464 1.00 6.99 ? 469 GLN A OE1 1 ATOM 3810 N NE2 . GLN A 1 469 ? 43.930 64.806 -4.312 1.00 6.91 ? 469 GLN A NE2 1 ATOM 3811 N N . HIS A 1 470 ? 41.156 64.845 0.925 1.00 5.57 ? 470 HIS A N 1 ATOM 3812 C CA . HIS A 1 470 ? 40.226 64.781 2.025 1.00 5.75 ? 470 HIS A CA 1 ATOM 3813 C C . HIS A 1 470 ? 38.795 65.030 1.558 1.00 5.92 ? 470 HIS A C 1 ATOM 3814 O O . HIS A 1 470 ? 38.553 65.802 0.627 1.00 6.43 ? 470 HIS A O 1 ATOM 3815 C CB . HIS A 1 470 ? 40.658 65.834 3.073 1.00 6.67 ? 470 HIS A CB 1 ATOM 3816 C CG . HIS A 1 470 ? 39.669 66.050 4.169 1.00 6.40 ? 470 HIS A CG 1 ATOM 3817 N ND1 . HIS A 1 470 ? 39.065 65.004 4.851 1.00 8.06 ? 470 HIS A ND1 1 ATOM 3818 C CD2 . HIS A 1 470 ? 39.170 67.200 4.682 1.00 6.81 ? 470 HIS A CD2 1 ATOM 3819 C CE1 . HIS A 1 470 ? 38.233 65.520 5.738 1.00 8.26 ? 470 HIS A CE1 1 ATOM 3820 N NE2 . HIS A 1 470 ? 38.277 66.839 5.662 1.00 7.74 ? 470 HIS A NE2 1 ATOM 3821 N N . HIS A 1 471 ? 37.830 64.403 2.247 1.00 6.04 ? 471 HIS A N 1 ATOM 3822 C CA . HIS A 1 471 ? 36.410 64.557 1.913 1.00 6.64 ? 471 HIS A CA 1 ATOM 3823 C C . HIS A 1 471 ? 35.805 65.926 2.250 1.00 6.92 ? 471 HIS A C 1 ATOM 3824 O O . HIS A 1 471 ? 34.605 66.108 1.988 1.00 7.91 ? 471 HIS A O 1 ATOM 3825 C CB . HIS A 1 471 ? 35.598 63.401 2.518 1.00 6.42 ? 471 HIS A CB 1 ATOM 3826 C CG . HIS A 1 471 ? 35.664 63.342 4.019 1.00 5.77 ? 471 HIS A CG 1 ATOM 3827 N ND1 . HIS A 1 471 ? 36.600 62.587 4.703 1.00 6.73 ? 471 HIS A ND1 1 ATOM 3828 C CD2 . HIS A 1 471 ? 34.903 63.962 4.970 1.00 5.91 ? 471 HIS A CD2 1 ATOM 3829 C CE1 . HIS A 1 471 ? 36.413 62.751 6.010 1.00 6.72 ? 471 HIS A CE1 1 ATOM 3830 N NE2 . HIS A 1 471 ? 35.406 63.593 6.198 1.00 6.64 ? 471 HIS A NE2 1 ATOM 3831 N N . ASP A 1 472 ? 36.602 66.884 2.744 1.00 6.97 ? 472 ASP A N 1 ATOM 3832 C CA . ASP A 1 472 ? 36.198 68.299 2.700 1.00 7.46 ? 472 ASP A CA 1 ATOM 3833 C C . ASP A 1 472 ? 37.155 69.154 1.867 1.00 7.80 ? 472 ASP A C 1 ATOM 3834 O O . ASP A 1 472 ? 37.016 70.384 1.896 1.00 8.20 ? 472 ASP A O 1 ATOM 3835 C CB . ASP A 1 472 ? 36.050 68.920 4.112 1.00 8.07 ? 472 ASP A CB 1 ATOM 3836 C CG . ASP A 1 472 ? 35.022 68.185 4.957 1.00 7.24 ? 472 ASP A CG 1 ATOM 3837 O OD1 . ASP A 1 472 ? 33.845 68.130 4.503 1.00 8.20 ? 472 ASP A OD1 1 ATOM 3838 O OD2 . ASP A 1 472 ? 35.364 67.637 6.007 1.00 8.41 ? 472 ASP A OD2 1 ATOM 3839 N N . GLY A 1 473 ? 38.094 68.545 1.142 1.00 6.53 ? 473 GLY A N 1 ATOM 3840 C CA . GLY A 1 473 ? 39.068 69.266 0.346 1.00 6.83 ? 473 GLY A CA 1 ATOM 3841 C C . GLY A 1 473 ? 38.529 69.358 -1.072 1.00 6.18 ? 473 GLY A C 1 ATOM 3842 O O . GLY A 1 473 ? 37.812 70.301 -1.430 1.00 6.65 ? 473 GLY A O 1 ATOM 3843 N N . ILE A 1 474 ? 38.861 68.360 -1.901 1.00 6.00 ? 474 ILE A N 1 ATOM 3844 C CA . ILE A 1 474 ? 38.427 68.336 -3.306 1.00 6.50 ? 474 ILE A CA 1 ATOM 3845 C C . ILE A 1 474 ? 36.903 68.461 -3.458 1.00 6.51 ? 474 ILE A C 1 ATOM 3846 O O . ILE A 1 474 ? 36.415 68.952 -4.491 1.00 6.96 ? 474 ILE A O 1 ATOM 3847 C CB . ILE A 1 474 ? 39.007 67.088 -3.974 1.00 5.62 ? 474 ILE A CB 1 ATOM 3848 C CG1 . ILE A 1 474 ? 38.759 67.124 -5.492 1.00 7.53 ? 474 ILE A CG1 1 ATOM 3849 C CG2 . ILE A 1 474 ? 38.473 65.785 -3.355 1.00 6.89 ? 474 ILE A CG2 1 ATOM 3850 C CD1 . ILE A 1 474 ? 39.494 65.973 -6.225 1.00 8.67 ? 474 ILE A CD1 1 ATOM 3851 N N . THR A 1 475 ? 36.162 68.040 -2.435 1.00 5.81 ? 475 THR A N 1 ATOM 3852 C CA . THR A 1 475 ? 34.690 68.115 -2.461 1.00 6.58 ? 475 THR A CA 1 ATOM 3853 C C . THR A 1 475 ? 34.153 69.538 -2.460 1.00 6.24 ? 475 THR A C 1 ATOM 3854 O O . THR A 1 475 ? 32.989 69.742 -2.817 1.00 6.94 ? 475 THR A O 1 ATOM 3855 C CB . THR A 1 475 ? 34.117 67.460 -1.226 1.00 6.46 ? 475 THR A CB 1 ATOM 3856 O OG1 . THR A 1 475 ? 34.652 68.158 -0.093 1.00 7.59 ? 475 THR A OG1 1 ATOM 3857 C CG2 . THR A 1 475 ? 34.498 65.976 -1.120 1.00 8.27 ? 475 THR A CG2 1 ATOM 3858 N N . GLY A 1 476 ? 34.965 70.529 -2.081 1.00 6.38 ? 476 GLY A N 1 ATOM 3859 C CA . GLY A 1 476 ? 34.465 71.899 -2.061 1.00 7.14 ? 476 GLY A CA 1 ATOM 3860 C C . GLY A 1 476 ? 33.490 72.169 -0.913 1.00 7.23 ? 476 GLY A C 1 ATOM 3861 O O . GLY A 1 476 ? 32.605 73.015 -1.046 1.00 7.77 ? 476 GLY A O 1 ATOM 3862 N N . THR A 1 477 ? 33.641 71.454 0.202 1.00 6.94 ? 477 THR A N 1 ATOM 3863 C CA . THR A 1 477 ? 32.735 71.583 1.331 1.00 7.59 ? 477 THR A CA 1 ATOM 3864 C C . THR A 1 477 ? 33.393 72.196 2.553 1.00 7.41 ? 477 THR A C 1 ATOM 3865 O O . THR A 1 477 ? 32.839 72.065 3.656 1.00 10.06 ? 477 THR A O 1 ATOM 3866 C CB . THR A 1 477 ? 32.089 70.240 1.688 1.00 7.85 ? 477 THR A CB 1 ATOM 3867 O OG1 . THR A 1 477 ? 33.110 69.253 1.936 1.00 8.30 ? 477 THR A OG1 1 ATOM 3868 C CG2 . THR A 1 477 ? 31.261 69.727 0.505 1.00 8.24 ? 477 THR A CG2 1 ATOM 3869 N N . ALA A 1 478 ? 34.499 72.936 2.383 1.00 7.84 ? 478 ALA A N 1 ATOM 3870 C CA . ALA A 1 478 ? 35.146 73.584 3.521 1.00 7.69 ? 478 ALA A CA 1 ATOM 3871 C C . ALA A 1 478 ? 34.838 75.079 3.576 1.00 7.64 ? 478 ALA A C 1 ATOM 3872 O O . ALA A 1 478 ? 34.347 75.690 2.632 1.00 8.13 ? 478 ALA A O 1 ATOM 3873 C CB . ALA A 1 478 ? 36.690 73.344 3.474 1.00 8.22 ? 478 ALA A CB 1 ATOM 3874 N N . LYS A 1 479 ? 35.110 75.670 4.736 1.00 8.18 ? 479 LYS A N 1 ATOM 3875 C CA . LYS A 1 479 ? 34.929 77.125 4.860 1.00 9.40 ? 479 LYS A CA 1 ATOM 3876 C C . LYS A 1 479 ? 35.900 77.854 3.945 1.00 8.91 ? 479 LYS A C 1 ATOM 3877 O O . LYS A 1 479 ? 36.968 77.350 3.591 1.00 8.19 ? 479 LYS A O 1 ATOM 3878 C CB . LYS A 1 479 ? 35.186 77.566 6.307 1.00 10.88 ? 479 LYS A CB 1 ATOM 3879 C CG . LYS A 1 479 ? 33.990 77.236 7.213 1.00 14.37 ? 479 LYS A CG 1 ATOM 3880 C CD . LYS A 1 479 ? 33.961 78.091 8.468 1.00 18.49 ? 479 LYS A CD 1 ATOM 3881 C CE . LYS A 1 479 ? 32.666 77.894 9.288 1.00 17.99 ? 479 LYS A CE 1 ATOM 3882 N NZ . LYS A 1 479 ? 31.469 78.563 8.696 1.00 19.76 ? 479 LYS A NZ 1 ATOM 3883 N N . THR A 1 480 ? 35.530 79.078 3.580 1.00 9.86 ? 480 THR A N 1 ATOM 3884 C CA . THR A 1 480 ? 36.330 79.873 2.666 1.00 10.17 ? 480 THR A CA 1 ATOM 3885 C C . THR A 1 480 ? 37.803 79.949 3.024 1.00 9.79 ? 480 THR A C 1 ATOM 3886 O O . THR A 1 480 ? 38.657 79.741 2.159 1.00 10.23 ? 480 THR A O 1 ATOM 3887 C CB . THR A 1 480 ? 35.734 81.294 2.578 1.00 12.43 ? 480 THR A CB 1 ATOM 3888 O OG1 . THR A 1 480 ? 34.428 81.147 2.020 1.00 14.65 ? 480 THR A OG1 1 ATOM 3889 C CG2 . THR A 1 480 ? 36.487 82.155 1.583 1.00 15.83 ? 480 THR A CG2 1 ATOM 3890 N N . HIS A 1 481 ? 38.140 80.236 4.287 1.00 9.73 ? 481 HIS A N 1 ATOM 3891 C CA . HIS A 1 481 ? 39.559 80.378 4.620 1.00 9.25 ? 481 HIS A CA 1 ATOM 3892 C C . HIS A 1 481 ? 40.296 79.053 4.579 1.00 9.70 ? 481 HIS A C 1 ATOM 3893 O O . HIS A 1 481 ? 41.503 79.016 4.413 1.00 9.60 ? 481 HIS A O 1 ATOM 3894 C CB . HIS A 1 481 ? 39.793 81.084 5.990 1.00 11.15 ? 481 HIS A CB 1 ATOM 3895 C CG . HIS A 1 481 ? 39.606 80.209 7.193 1.00 11.60 ? 481 HIS A CG 1 ATOM 3896 N ND1 . HIS A 1 481 ? 38.367 79.795 7.636 1.00 13.38 ? 481 HIS A ND1 1 ATOM 3897 C CD2 . HIS A 1 481 ? 40.511 79.692 8.060 1.00 12.10 ? 481 HIS A CD2 1 ATOM 3898 C CE1 . HIS A 1 481 ? 38.525 79.057 8.725 1.00 12.62 ? 481 HIS A CE1 1 ATOM 3899 N NE2 . HIS A 1 481 ? 39.814 78.979 9.002 1.00 13.43 ? 481 HIS A NE2 1 ATOM 3900 N N . VAL A 1 482 ? 39.556 77.956 4.712 1.00 8.76 ? 482 VAL A N 1 ATOM 3901 C CA . VAL A 1 482 ? 40.159 76.640 4.633 1.00 8.73 ? 482 VAL A CA 1 ATOM 3902 C C . VAL A 1 482 ? 40.425 76.290 3.146 1.00 7.49 ? 482 VAL A C 1 ATOM 3903 O O . VAL A 1 482 ? 41.486 75.764 2.815 1.00 8.22 ? 482 VAL A O 1 ATOM 3904 C CB . VAL A 1 482 ? 39.246 75.608 5.293 1.00 8.08 ? 482 VAL A CB 1 ATOM 3905 C CG1 . VAL A 1 482 ? 39.883 74.215 5.185 1.00 8.76 ? 482 VAL A CG1 1 ATOM 3906 C CG2 . VAL A 1 482 ? 39.016 75.957 6.791 1.00 9.69 ? 482 VAL A CG2 1 ATOM 3907 N N . VAL A 1 483 ? 39.493 76.619 2.252 1.00 7.50 ? 483 VAL A N 1 ATOM 3908 C CA . VAL A 1 483 ? 39.751 76.470 0.826 1.00 8.10 ? 483 VAL A CA 1 ATOM 3909 C C . VAL A 1 483 ? 41.004 77.252 0.425 1.00 8.06 ? 483 VAL A C 1 ATOM 3910 O O . VAL A 1 483 ? 41.841 76.762 -0.338 1.00 8.69 ? 483 VAL A O 1 ATOM 3911 C CB . VAL A 1 483 ? 38.527 76.959 0.020 1.00 7.81 ? 483 VAL A CB 1 ATOM 3912 C CG1 . VAL A 1 483 ? 38.781 76.909 -1.491 1.00 10.60 ? 483 VAL A CG1 1 ATOM 3913 C CG2 . VAL A 1 483 ? 37.300 76.086 0.367 1.00 9.30 ? 483 VAL A CG2 1 ATOM 3914 N N . VAL A 1 484 ? 41.129 78.471 0.941 1.00 9.03 ? 484 VAL A N 1 ATOM 3915 C CA . VAL A 1 484 ? 42.322 79.278 0.707 1.00 9.87 ? 484 VAL A CA 1 ATOM 3916 C C . VAL A 1 484 ? 43.594 78.581 1.166 1.00 8.85 ? 484 VAL A C 1 ATOM 3917 O O . VAL A 1 484 ? 44.566 78.550 0.437 1.00 9.50 ? 484 VAL A O 1 ATOM 3918 C CB . VAL A 1 484 ? 42.210 80.685 1.316 1.00 10.10 ? 484 VAL A CB 1 ATOM 3919 C CG1 . VAL A 1 484 ? 43.559 81.410 1.244 1.00 11.99 ? 484 VAL A CG1 1 ATOM 3920 C CG2 . VAL A 1 484 ? 41.133 81.480 0.591 1.00 12.99 ? 484 VAL A CG2 1 ATOM 3921 N N . ASP A 1 485 ? 43.566 77.994 2.352 1.00 8.74 ? 485 ASP A N 1 ATOM 3922 C CA . ASP A 1 485 ? 44.684 77.187 2.827 1.00 8.50 ? 485 ASP A CA 1 ATOM 3923 C C . ASP A 1 485 ? 45.035 76.042 1.882 1.00 9.12 ? 485 ASP A C 1 ATOM 3924 O O . ASP A 1 485 ? 46.189 75.859 1.567 1.00 8.85 ? 485 ASP A O 1 ATOM 3925 C CB . ASP A 1 485 ? 44.440 76.671 4.251 1.00 9.33 ? 485 ASP A CB 1 ATOM 3926 C CG . ASP A 1 485 ? 45.686 76.061 4.870 1.00 11.06 ? 485 ASP A CG 1 ATOM 3927 O OD1 . ASP A 1 485 ? 46.678 76.786 5.019 1.00 15.37 ? 485 ASP A OD1 1 ATOM 3928 O OD2 . ASP A 1 485 ? 45.683 74.884 5.215 1.00 10.48 ? 485 ASP A OD2 1 ATOM 3929 N N . TYR A 1 486 ? 44.045 75.280 1.434 1.00 7.37 ? 486 TYR A N 1 ATOM 3930 C CA . TYR A 1 486 ? 44.312 74.186 0.497 1.00 7.52 ? 486 TYR A CA 1 ATOM 3931 C C . TYR A 1 486 ? 44.931 74.723 -0.789 1.00 7.34 ? 486 TYR A C 1 ATOM 3932 O O . TYR A 1 486 ? 45.840 74.141 -1.314 1.00 7.61 ? 486 TYR A O 1 ATOM 3933 C CB . TYR A 1 486 ? 43.027 73.416 0.158 1.00 8.43 ? 486 TYR A CB 1 ATOM 3934 C CG . TYR A 1 486 ? 42.434 72.545 1.274 1.00 7.91 ? 486 TYR A CG 1 ATOM 3935 C CD1 . TYR A 1 486 ? 43.227 71.686 2.043 1.00 9.84 ? 486 TYR A CD1 1 ATOM 3936 C CD2 . TYR A 1 486 ? 41.066 72.548 1.512 1.00 8.42 ? 486 TYR A CD2 1 ATOM 3937 C CE1 . TYR A 1 486 ? 42.654 70.876 3.033 1.00 10.37 ? 486 TYR A CE1 1 ATOM 3938 C CE2 . TYR A 1 486 ? 40.503 71.750 2.491 1.00 8.24 ? 486 TYR A CE2 1 ATOM 3939 C CZ . TYR A 1 486 ? 41.288 70.920 3.237 1.00 8.53 ? 486 TYR A CZ 1 ATOM 3940 O OH . TYR A 1 486 ? 40.667 70.145 4.194 1.00 10.50 ? 486 TYR A OH 1 ATOM 3941 N N . GLU A 1 487 ? 44.412 75.834 -1.282 1.00 8.42 ? 487 GLU A N 1 ATOM 3942 C CA . GLU A 1 487 ? 44.904 76.428 -2.528 1.00 8.55 ? 487 GLU A CA 1 ATOM 3943 C C . GLU A 1 487 ? 46.362 76.859 -2.371 1.00 9.13 ? 487 GLU A C 1 ATOM 3944 O O . GLU A 1 487 ? 47.224 76.587 -3.240 1.00 9.15 ? 487 GLU A O 1 ATOM 3945 C CB . GLU A 1 487 ? 44.045 77.623 -2.931 1.00 8.97 ? 487 GLU A CB 1 ATOM 3946 C CG . GLU A 1 487 ? 44.467 78.186 -4.277 1.00 11.39 ? 487 GLU A CG 1 ATOM 3947 C CD . GLU A 1 487 ? 43.626 79.331 -4.744 1.00 15.67 ? 487 GLU A CD 1 ATOM 3948 O OE1 . GLU A 1 487 ? 42.483 79.511 -4.277 1.00 16.13 ? 487 GLU A OE1 1 ATOM 3949 O OE2 . GLU A 1 487 ? 44.131 80.044 -5.645 1.00 19.98 ? 487 GLU A OE2 1 ATOM 3950 N N . GLN A 1 488 ? 46.677 77.529 -1.268 1.00 9.27 ? 488 GLN A N 1 ATOM 3951 C CA . GLN A 1 488 ? 48.070 77.971 -1.006 1.00 10.48 ? 488 GLN A CA 1 ATOM 3952 C C . GLN A 1 488 ? 48.993 76.780 -0.908 1.00 9.90 ? 488 GLN A C 1 ATOM 3953 O O . GLN A 1 488 ? 50.121 76.803 -1.461 1.00 9.68 ? 488 GLN A O 1 ATOM 3954 C CB . GLN A 1 488 ? 48.158 78.776 0.309 1.00 12.69 ? 488 GLN A CB 1 ATOM 3955 C CG . GLN A 1 488 ? 47.419 80.065 0.260 1.00 17.89 ? 488 GLN A CG 1 ATOM 3956 C CD . GLN A 1 488 ? 47.390 80.764 1.616 1.00 23.72 ? 488 GLN A CD 1 ATOM 3957 O OE1 . GLN A 1 488 ? 47.628 80.151 2.674 1.00 27.40 ? 488 GLN A OE1 1 ATOM 3958 N NE2 . GLN A 1 488 ? 47.081 82.035 1.590 1.00 26.94 ? 488 GLN A NE2 1 ATOM 3959 N N . ARG A 1 489 ? 48.557 75.719 -0.242 1.00 8.63 ? 489 ARG A N 1 ATOM 3960 C CA . ARG A 1 489 ? 49.359 74.501 -0.142 1.00 8.99 ? 489 ARG A CA 1 ATOM 3961 C C . ARG A 1 489 ? 49.591 73.899 -1.525 1.00 8.50 ? 489 ARG A C 1 ATOM 3962 O O . ARG A 1 489 ? 50.704 73.534 -1.873 1.00 8.12 ? 489 ARG A O 1 ATOM 3963 C CB . ARG A 1 489 ? 48.682 73.497 0.764 1.00 8.25 ? 489 ARG A CB 1 ATOM 3964 C CG . ARG A 1 489 ? 48.764 73.840 2.215 1.00 8.72 ? 489 ARG A CG 1 ATOM 3965 C CD . ARG A 1 489 ? 47.768 72.956 3.028 1.00 10.90 ? 489 ARG A CD 1 ATOM 3966 N NE . ARG A 1 489 ? 47.881 73.106 4.487 1.00 10.78 ? 489 ARG A NE 1 ATOM 3967 C CZ . ARG A 1 489 ? 48.735 72.443 5.262 1.00 11.98 ? 489 ARG A CZ 1 ATOM 3968 N NH1 . ARG A 1 489 ? 49.587 71.557 4.774 1.00 13.06 ? 489 ARG A NH1 1 ATOM 3969 N NH2 . ARG A 1 489 ? 48.726 72.697 6.570 1.00 13.60 ? 489 ARG A NH2 1 ATOM 3970 N N . MET A 1 490 ? 48.557 73.835 -2.361 1.00 7.41 ? 490 MET A N 1 ATOM 3971 C CA . MET A 1 490 ? 48.722 73.279 -3.700 1.00 7.88 ? 490 MET A CA 1 ATOM 3972 C C . MET A 1 490 ? 49.599 74.170 -4.576 1.00 8.17 ? 490 MET A C 1 ATOM 3973 O O . MET A 1 490 ? 50.330 73.667 -5.441 1.00 8.45 ? 490 MET A O 1 ATOM 3974 C CB . MET A 1 490 ? 47.362 73.042 -4.365 1.00 7.53 ? 490 MET A CB 1 ATOM 3975 C CG . MET A 1 490 ? 46.612 71.860 -3.726 1.00 9.01 ? 490 MET A CG 1 ATOM 3976 S SD . MET A 1 490 ? 45.310 71.131 -4.810 1.00 10.91 ? 490 MET A SD 1 ATOM 3977 C CE . MET A 1 490 ? 44.037 72.314 -4.455 1.00 13.16 ? 490 MET A CE 1 ATOM 3978 N N . GLN A 1 491 ? 49.516 75.484 -4.377 1.00 8.03 ? 491 GLN A N 1 ATOM 3979 C CA . GLN A 1 491 ? 50.410 76.381 -5.136 1.00 9.77 ? 491 GLN A CA 1 ATOM 3980 C C . GLN A 1 491 ? 51.878 76.145 -4.799 1.00 9.33 ? 491 GLN A C 1 ATOM 3981 O O . GLN A 1 491 ? 52.751 76.079 -5.694 1.00 9.89 ? 491 GLN A O 1 ATOM 3982 C CB . GLN A 1 491 ? 50.077 77.842 -4.859 1.00 11.09 ? 491 GLN A CB 1 ATOM 3983 C CG . GLN A 1 491 ? 50.889 78.753 -5.794 1.00 15.89 ? 491 GLN A CG 1 ATOM 3984 C CD . GLN A 1 491 ? 50.766 78.354 -7.256 1.00 24.02 ? 491 GLN A CD 1 ATOM 3985 O OE1 . GLN A 1 491 ? 49.673 78.141 -7.738 1.00 28.85 ? 491 GLN A OE1 1 ATOM 3986 N NE2 . GLN A 1 491 ? 51.900 78.210 -7.946 1.00 25.78 ? 491 GLN A NE2 1 ATOM 3987 N N . GLU A 1 492 ? 52.162 75.936 -3.516 1.00 9.54 ? 492 GLU A N 1 ATOM 3988 C CA . GLU A 1 492 ? 53.511 75.612 -3.095 1.00 10.79 ? 492 GLU A CA 1 ATOM 3989 C C . GLU A 1 492 ? 53.932 74.281 -3.702 1.00 9.79 ? 492 GLU A C 1 ATOM 3990 O O . GLU A 1 492 ? 55.077 74.105 -4.154 1.00 10.06 ? 492 GLU A O 1 ATOM 3991 C CB . GLU A 1 492 ? 53.589 75.560 -1.563 1.00 12.37 ? 492 GLU A CB 1 ATOM 3992 C CG . GLU A 1 492 ? 53.523 76.916 -0.871 1.00 19.03 ? 492 GLU A CG 1 ATOM 3993 C CD . GLU A 1 492 ? 54.482 77.941 -1.461 1.00 24.97 ? 492 GLU A CD 1 ATOM 3994 O OE1 . GLU A 1 492 ? 55.704 77.662 -1.559 1.00 29.92 ? 492 GLU A OE1 1 ATOM 3995 O OE2 . GLU A 1 492 ? 54.014 79.043 -1.824 1.00 30.27 ? 492 GLU A OE2 1 ATOM 3996 N N . ALA A 1 493 ? 53.011 73.319 -3.745 1.00 8.52 ? 493 ALA A N 1 ATOM 3997 C CA . ALA A 1 493 ? 53.307 72.007 -4.336 1.00 7.44 ? 493 ALA A CA 1 ATOM 3998 C C . ALA A 1 493 ? 53.624 72.140 -5.853 1.00 7.89 ? 493 ALA A C 1 ATOM 3999 O O . ALA A 1 493 ? 54.526 71.467 -6.358 1.00 7.66 ? 493 ALA A O 1 ATOM 4000 C CB . ALA A 1 493 ? 52.116 71.045 -4.090 1.00 8.05 ? 493 ALA A CB 1 ATOM 4001 N N . LEU A 1 494 ? 52.880 72.982 -6.572 1.00 7.47 ? 494 LEU A N 1 ATOM 4002 C CA . LEU A 1 494 ? 53.158 73.211 -7.995 1.00 7.80 ? 494 LEU A CA 1 ATOM 4003 C C . LEU A 1 494 ? 54.551 73.798 -8.169 1.00 8.11 ? 494 LEU A C 1 ATOM 4004 O O . LEU A 1 494 ? 55.280 73.377 -9.073 1.00 8.18 ? 494 LEU A O 1 ATOM 4005 C CB . LEU A 1 494 ? 52.110 74.143 -8.606 1.00 8.15 ? 494 LEU A CB 1 ATOM 4006 C CG . LEU A 1 494 ? 50.742 73.482 -8.830 1.00 8.30 ? 494 LEU A CG 1 ATOM 4007 C CD1 . LEU A 1 494 ? 49.693 74.552 -9.154 1.00 10.55 ? 494 LEU A CD1 1 ATOM 4008 C CD2 . LEU A 1 494 ? 50.795 72.448 -9.935 1.00 9.47 ? 494 LEU A CD2 1 ATOM 4009 N N . LYS A 1 495 ? 54.938 74.739 -7.315 1.00 8.73 ? 495 LYS A N 1 ATOM 4010 C CA . LYS A 1 495 ? 56.284 75.330 -7.410 1.00 9.11 ? 495 LYS A CA 1 ATOM 4011 C C . LYS A 1 495 ? 57.335 74.289 -7.125 1.00 8.75 ? 495 LYS A C 1 ATOM 4012 O O . LYS A 1 495 ? 58.377 74.257 -7.805 1.00 9.22 ? 495 LYS A O 1 ATOM 4013 C CB . LYS A 1 495 ? 56.404 76.494 -6.449 1.00 11.25 ? 495 LYS A CB 1 ATOM 4014 C CG . LYS A 1 495 ? 55.551 77.662 -6.875 1.00 14.80 ? 495 LYS A CG 1 ATOM 4015 C CD . LYS A 1 495 ? 55.767 78.898 -6.014 1.00 22.95 ? 495 LYS A CD 1 ATOM 4016 C CE . LYS A 1 495 ? 55.056 78.804 -4.700 1.00 27.19 ? 495 LYS A CE 1 ATOM 4017 N NZ . LYS A 1 495 ? 55.247 80.061 -3.901 1.00 31.22 ? 495 LYS A NZ 1 ATOM 4018 N N . ALA A 1 496 ? 57.080 73.406 -6.160 1.00 7.78 ? 496 ALA A N 1 ATOM 4019 C CA . ALA A 1 496 ? 58.011 72.342 -5.856 1.00 8.08 ? 496 ALA A CA 1 ATOM 4020 C C . ALA A 1 496 ? 58.187 71.423 -7.079 1.00 8.31 ? 496 ALA A C 1 ATOM 4021 O O . ALA A 1 496 ? 59.302 71.023 -7.436 1.00 8.77 ? 496 ALA A O 1 ATOM 4022 C CB . ALA A 1 496 ? 57.509 71.528 -4.619 1.00 8.91 ? 496 ALA A CB 1 ATOM 4023 N N . CYS A 1 497 ? 57.078 71.039 -7.713 1.00 7.67 ? 497 CYS A N 1 ATOM 4024 C CA . CYS A 1 497 ? 57.133 70.185 -8.903 1.00 7.23 ? 497 CYS A CA 1 ATOM 4025 C C . CYS A 1 497 ? 57.893 70.871 -10.022 1.00 8.10 ? 497 CYS A C 1 ATOM 4026 O O . CYS A 1 497 ? 58.719 70.238 -10.663 1.00 7.72 ? 497 CYS A O 1 ATOM 4027 C CB . CYS A 1 497 ? 55.713 69.846 -9.378 1.00 7.72 ? 497 CYS A CB 1 ATOM 4028 S SG . CYS A 1 497 ? 54.824 68.698 -8.317 1.00 8.86 ? 497 CYS A SG 1 ATOM 4029 N N . GLN A 1 498 ? 57.632 72.148 -10.229 1.00 8.04 ? 498 GLN A N 1 ATOM 4030 C CA . GLN A 1 498 ? 58.344 72.872 -11.283 1.00 8.92 ? 498 GLN A CA 1 ATOM 4031 C C . GLN A 1 498 ? 59.829 72.837 -11.016 1.00 8.60 ? 498 GLN A C 1 ATOM 4032 O O . GLN A 1 498 ? 60.618 72.605 -11.958 1.00 8.41 ? 498 GLN A O 1 ATOM 4033 C CB . GLN A 1 498 ? 57.885 74.316 -11.346 1.00 8.89 ? 498 GLN A CB 1 ATOM 4034 C CG . GLN A 1 498 ? 58.733 75.130 -12.317 1.00 12.76 ? 498 GLN A CG 1 ATOM 4035 C CD . GLN A 1 498 ? 58.220 76.544 -12.526 1.00 13.68 ? 498 GLN A CD 1 ATOM 4036 O OE1 . GLN A 1 498 ? 57.937 76.948 -13.660 1.00 14.55 ? 498 GLN A OE1 1 ATOM 4037 N NE2 . GLN A 1 498 ? 58.130 77.320 -11.429 1.00 16.11 ? 498 GLN A NE2 1 ATOM 4038 N N . MET A 1 499 ? 60.252 73.074 -9.785 1.00 7.89 ? 499 MET A N 1 ATOM 4039 C CA . MET A 1 499 ? 61.676 73.102 -9.459 1.00 8.88 ? 499 MET A CA 1 ATOM 4040 C C . MET A 1 499 ? 62.326 71.756 -9.778 1.00 9.11 ? 499 MET A C 1 ATOM 4041 O O . MET A 1 499 ? 63.364 71.694 -10.404 1.00 9.64 ? 499 MET A O 1 ATOM 4042 C CB . MET A 1 499 ? 61.864 73.474 -7.987 1.00 9.77 ? 499 MET A CB 1 ATOM 4043 C CG . MET A 1 499 ? 63.300 73.302 -7.458 1.00 11.50 ? 499 MET A CG 1 ATOM 4044 S SD . MET A 1 499 ? 64.592 74.300 -8.253 1.00 16.76 ? 499 MET A SD 1 ATOM 4045 C CE . MET A 1 499 ? 64.009 75.915 -7.809 1.00 17.90 ? 499 MET A CE 1 ATOM 4046 N N . VAL A 1 500 ? 61.681 70.678 -9.354 1.00 8.29 ? 500 VAL A N 1 ATOM 4047 C CA . VAL A 1 500 ? 62.240 69.361 -9.543 1.00 7.88 ? 500 VAL A CA 1 ATOM 4048 C C . VAL A 1 500 ? 62.265 69.040 -11.045 1.00 8.02 ? 500 VAL A C 1 ATOM 4049 O O . VAL A 1 500 ? 63.255 68.498 -11.555 1.00 8.18 ? 500 VAL A O 1 ATOM 4050 C CB . VAL A 1 500 ? 61.441 68.294 -8.769 1.00 8.30 ? 500 VAL A CB 1 ATOM 4051 C CG1 . VAL A 1 500 ? 61.871 66.920 -9.166 1.00 8.34 ? 500 VAL A CG1 1 ATOM 4052 C CG2 . VAL A 1 500 ? 61.688 68.500 -7.270 1.00 9.96 ? 500 VAL A CG2 1 ATOM 4053 N N . MET A 1 501 ? 61.192 69.354 -11.749 1.00 7.71 ? 501 MET A N 1 ATOM 4054 C CA . MET A 1 501 ? 61.107 69.062 -13.176 1.00 8.31 ? 501 MET A CA 1 ATOM 4055 C C . MET A 1 501 ? 62.201 69.776 -13.948 1.00 7.84 ? 501 MET A C 1 ATOM 4056 O O . MET A 1 501 ? 62.874 69.168 -14.768 1.00 8.35 ? 501 MET A O 1 ATOM 4057 C CB . MET A 1 501 ? 59.732 69.440 -13.715 1.00 8.28 ? 501 MET A CB 1 ATOM 4058 C CG . MET A 1 501 ? 58.632 68.490 -13.248 1.00 8.65 ? 501 MET A CG 1 ATOM 4059 S SD . MET A 1 501 ? 56.965 69.112 -13.571 1.00 12.34 ? 501 MET A SD 1 ATOM 4060 C CE . MET A 1 501 ? 56.869 68.825 -15.319 1.00 13.84 ? 501 MET A CE 1 ATOM 4061 N N . GLN A 1 502 ? 62.391 71.059 -13.673 1.00 7.98 ? 502 GLN A N 1 ATOM 4062 C CA . GLN A 1 502 ? 63.314 71.835 -14.521 1.00 8.37 ? 502 GLN A CA 1 ATOM 4063 C C . GLN A 1 502 ? 64.774 71.466 -14.191 1.00 9.71 ? 502 GLN A C 1 ATOM 4064 O O . GLN A 1 502 ? 65.601 71.399 -15.121 1.00 10.05 ? 502 GLN A O 1 ATOM 4065 C CB . GLN A 1 502 ? 63.024 73.319 -14.411 1.00 9.94 ? 502 GLN A CB 1 ATOM 4066 C CG . GLN A 1 502 ? 63.224 73.945 -13.053 1.00 10.36 ? 502 GLN A CG 1 ATOM 4067 C CD . GLN A 1 502 ? 64.637 74.485 -12.839 1.00 12.27 ? 502 GLN A CD 1 ATOM 4068 O OE1 . GLN A 1 502 ? 65.432 74.619 -13.786 1.00 12.44 ? 502 GLN A OE1 1 ATOM 4069 N NE2 . GLN A 1 502 ? 64.964 74.789 -11.594 1.00 13.40 ? 502 GLN A NE2 1 ATOM 4070 N N . GLN A 1 503 ? 65.085 71.154 -12.938 1.00 8.80 ? 503 GLN A N 1 ATOM 4071 C CA . GLN A 1 503 ? 66.433 70.623 -12.639 1.00 9.47 ? 503 GLN A CA 1 ATOM 4072 C C . GLN A 1 503 ? 66.657 69.317 -13.365 1.00 9.71 ? 503 GLN A C 1 ATOM 4073 O O . GLN A 1 503 ? 67.755 69.022 -13.886 1.00 9.64 ? 503 GLN A O 1 ATOM 4074 C CB . GLN A 1 503 ? 66.621 70.381 -11.138 1.00 10.12 ? 503 GLN A CB 1 ATOM 4075 C CG . GLN A 1 503 ? 66.754 71.643 -10.296 1.00 11.32 ? 503 GLN A CG 1 ATOM 4076 C CD . GLN A 1 503 ? 68.106 72.348 -10.453 1.00 13.46 ? 503 GLN A CD 1 ATOM 4077 O OE1 . GLN A 1 503 ? 69.110 71.707 -10.745 1.00 14.68 ? 503 GLN A OE1 1 ATOM 4078 N NE2 . GLN A 1 503 ? 68.117 73.655 -10.251 1.00 14.37 ? 503 GLN A NE2 1 ATOM 4079 N N . SER A 1 504 ? 65.630 68.469 -13.410 1.00 7.75 ? 504 SER A N 1 ATOM 4080 C CA . SER A 1 504 ? 65.753 67.172 -14.065 1.00 9.03 ? 504 SER A CA 1 ATOM 4081 C C . SER A 1 504 ? 65.976 67.296 -15.584 1.00 8.76 ? 504 SER A C 1 ATOM 4082 O O . SER A 1 504 ? 66.841 66.610 -16.158 1.00 9.20 ? 504 SER A O 1 ATOM 4083 C CB . SER A 1 504 ? 64.513 66.297 -13.812 1.00 9.31 ? 504 SER A CB 1 ATOM 4084 O OG . SER A 1 504 ? 64.387 66.006 -12.407 1.00 9.91 ? 504 SER A OG 1 ATOM 4085 N N . VAL A 1 505 ? 65.217 68.182 -16.214 1.00 8.33 ? 505 VAL A N 1 ATOM 4086 C CA . VAL A 1 505 ? 65.357 68.408 -17.656 1.00 8.80 ? 505 VAL A CA 1 ATOM 4087 C C . VAL A 1 505 ? 66.797 68.902 -17.954 1.00 9.31 ? 505 VAL A C 1 ATOM 4088 O O . VAL A 1 505 ? 67.456 68.430 -18.900 1.00 10.44 ? 505 VAL A O 1 ATOM 4089 C CB . VAL A 1 505 ? 64.301 69.416 -18.145 1.00 9.77 ? 505 VAL A CB 1 ATOM 4090 C CG1 . VAL A 1 505 ? 64.591 69.847 -19.602 1.00 10.72 ? 505 VAL A CG1 1 ATOM 4091 C CG2 . VAL A 1 505 ? 62.894 68.811 -18.034 1.00 10.57 ? 505 VAL A CG2 1 ATOM 4092 N N . TYR A 1 506 ? 67.271 69.842 -17.169 1.00 9.50 ? 506 TYR A N 1 ATOM 4093 C CA . TYR A 1 506 ? 68.609 70.347 -17.408 1.00 10.79 ? 506 TYR A CA 1 ATOM 4094 C C . TYR A 1 506 ? 69.643 69.212 -17.308 1.00 11.30 ? 506 TYR A C 1 ATOM 4095 O O . TYR A 1 506 ? 70.556 69.075 -18.146 1.00 12.17 ? 506 TYR A O 1 ATOM 4096 C CB . TYR A 1 506 ? 68.890 71.480 -16.437 1.00 12.34 ? 506 TYR A CB 1 ATOM 4097 C CG . TYR A 1 506 ? 70.179 72.193 -16.723 1.00 15.81 ? 506 TYR A CG 1 ATOM 4098 C CD1 . TYR A 1 506 ? 70.338 72.898 -17.936 1.00 18.02 ? 506 TYR A CD1 1 ATOM 4099 C CD2 . TYR A 1 506 ? 71.210 72.193 -15.797 1.00 15.99 ? 506 TYR A CD2 1 ATOM 4100 C CE1 . TYR A 1 506 ? 71.510 73.577 -18.227 1.00 19.73 ? 506 TYR A CE1 1 ATOM 4101 C CE2 . TYR A 1 506 ? 72.429 72.874 -16.087 1.00 19.79 ? 506 TYR A CE2 1 ATOM 4102 C CZ . TYR A 1 506 ? 72.545 73.538 -17.308 1.00 18.97 ? 506 TYR A CZ 1 ATOM 4103 O OH . TYR A 1 506 ? 73.690 74.244 -17.622 1.00 19.36 ? 506 TYR A OH 1 ATOM 4104 N N . ARG A 1 507 ? 69.511 68.349 -16.309 1.00 10.65 ? 507 ARG A N 1 ATOM 4105 C CA . ARG A 1 507 ? 70.445 67.232 -16.183 1.00 10.83 ? 507 ARG A CA 1 ATOM 4106 C C . ARG A 1 507 ? 70.315 66.225 -17.326 1.00 11.31 ? 507 ARG A C 1 ATOM 4107 O O . ARG A 1 507 ? 71.312 65.682 -17.813 1.00 11.06 ? 507 ARG A O 1 ATOM 4108 C CB . ARG A 1 507 ? 70.229 66.554 -14.832 1.00 11.16 ? 507 ARG A CB 1 ATOM 4109 C CG . ARG A 1 507 ? 71.297 65.499 -14.473 1.00 13.58 ? 507 ARG A CG 1 ATOM 4110 C CD . ARG A 1 507 ? 71.214 65.127 -13.012 1.00 14.29 ? 507 ARG A CD 1 ATOM 4111 N NE . ARG A 1 507 ? 72.206 64.100 -12.655 1.00 16.90 ? 507 ARG A NE 1 ATOM 4112 C CZ . ARG A 1 507 ? 72.245 63.472 -11.472 1.00 17.52 ? 507 ARG A CZ 1 ATOM 4113 N NH1 . ARG A 1 507 ? 71.364 63.772 -10.526 1.00 18.56 ? 507 ARG A NH1 1 ATOM 4114 N NH2 . ARG A 1 507 ? 73.147 62.514 -11.253 1.00 19.36 ? 507 ARG A NH2 1 ATOM 4115 N N . LEU A 1 508 ? 69.102 65.930 -17.752 1.00 9.27 ? 508 LEU A N 1 ATOM 4116 C CA . LEU A 1 508 ? 68.891 64.897 -18.740 1.00 9.26 ? 508 LEU A CA 1 ATOM 4117 C C . LEU A 1 508 ? 69.327 65.306 -20.136 1.00 10.15 ? 508 LEU A C 1 ATOM 4118 O O . LEU A 1 508 ? 69.550 64.444 -20.979 1.00 11.95 ? 508 LEU A O 1 ATOM 4119 C CB . LEU A 1 508 ? 67.410 64.511 -18.771 1.00 9.32 ? 508 LEU A CB 1 ATOM 4120 C CG . LEU A 1 508 ? 66.969 63.684 -17.541 1.00 8.91 ? 508 LEU A CG 1 ATOM 4121 C CD1 . LEU A 1 508 ? 65.427 63.745 -17.424 1.00 11.27 ? 508 LEU A CD1 1 ATOM 4122 C CD2 . LEU A 1 508 ? 67.432 62.234 -17.665 1.00 12.53 ? 508 LEU A CD2 1 ATOM 4123 N N . LEU A 1 509 ? 69.383 66.612 -20.376 1.00 10.45 ? 509 LEU A N 1 ATOM 4124 C CA . LEU A 1 509 ? 69.633 67.140 -21.716 1.00 10.48 ? 509 LEU A CA 1 ATOM 4125 C C . LEU A 1 509 ? 70.915 67.970 -21.809 1.00 11.63 ? 509 LEU A C 1 ATOM 4126 O O . LEU A 1 509 ? 71.077 68.685 -22.802 1.00 11.89 ? 509 LEU A O 1 ATOM 4127 C CB . LEU A 1 509 ? 68.409 67.938 -22.210 1.00 10.57 ? 509 LEU A CB 1 ATOM 4128 C CG . LEU A 1 509 ? 67.185 67.083 -22.553 1.00 10.30 ? 509 LEU A CG 1 ATOM 4129 C CD1 . LEU A 1 509 ? 66.030 68.026 -22.966 1.00 10.07 ? 509 LEU A CD1 1 ATOM 4130 C CD2 . LEU A 1 509 ? 67.437 66.094 -23.700 1.00 12.25 ? 509 LEU A CD2 1 ATOM 4131 N N . THR A 1 510 ? 71.829 67.862 -20.842 1.00 11.33 ? 510 THR A N 1 ATOM 4132 C CA . THR A 1 510 ? 73.108 68.576 -20.945 1.00 12.64 ? 510 THR A CA 1 ATOM 4133 C C . THR A 1 510 ? 74.246 67.562 -20.954 1.00 13.59 ? 510 THR A C 1 ATOM 4134 O O . THR A 1 510 ? 74.243 66.581 -20.197 1.00 13.34 ? 510 THR A O 1 ATOM 4135 C CB . THR A 1 510 ? 73.244 69.537 -19.767 1.00 11.93 ? 510 THR A CB 1 ATOM 4136 O OG1 . THR A 1 510 ? 72.172 70.492 -19.811 1.00 12.34 ? 510 THR A OG1 1 ATOM 4137 C CG2 . THR A 1 510 ? 74.560 70.403 -19.831 1.00 12.71 ? 510 THR A CG2 1 ATOM 4138 N N . LYS A 1 511 ? 75.215 67.789 -21.845 1.00 15.19 ? 511 LYS A N 1 ATOM 4139 C CA . LYS A 1 511 ? 76.387 66.911 -21.938 1.00 15.66 ? 511 LYS A CA 1 ATOM 4140 C C . LYS A 1 511 ? 76.967 66.730 -20.553 1.00 15.20 ? 511 LYS A C 1 ATOM 4141 O O . LYS A 1 511 ? 77.207 67.686 -19.852 1.00 14.31 ? 511 LYS A O 1 ATOM 4142 C CB . LYS A 1 511 ? 77.437 67.565 -22.829 1.00 16.59 ? 511 LYS A CB 1 ATOM 4143 C CG . LYS A 1 511 ? 78.678 66.703 -23.061 1.00 20.38 ? 511 LYS A CG 1 ATOM 4144 C CD . LYS A 1 511 ? 79.543 67.339 -24.117 1.00 25.56 ? 511 LYS A CD 1 ATOM 4145 C CE . LYS A 1 511 ? 80.749 66.470 -24.413 1.00 30.35 ? 511 LYS A CE 1 ATOM 4146 N NZ . LYS A 1 511 ? 81.627 67.150 -25.403 1.00 33.44 ? 511 LYS A NZ 1 ATOM 4147 N N . PRO A 1 512 ? 77.160 65.481 -20.138 1.00 16.61 ? 512 PRO A N 1 ATOM 4148 C CA . PRO A 1 512 ? 77.559 65.206 -18.755 1.00 17.30 ? 512 PRO A CA 1 ATOM 4149 C C . PRO A 1 512 ? 78.832 65.928 -18.270 1.00 16.38 ? 512 PRO A C 1 ATOM 4150 O O . PRO A 1 512 ? 78.863 66.407 -17.149 1.00 16.65 ? 512 PRO A O 1 ATOM 4151 C CB . PRO A 1 512 ? 77.757 63.690 -18.752 1.00 18.44 ? 512 PRO A CB 1 ATOM 4152 C CG . PRO A 1 512 ? 76.855 63.214 -19.829 1.00 19.31 ? 512 PRO A CG 1 ATOM 4153 C CD . PRO A 1 512 ? 76.893 64.245 -20.907 1.00 18.03 ? 512 PRO A CD 1 ATOM 4154 N N . SER A 1 513 ? 79.848 66.059 -19.131 1.00 16.66 ? 513 SER A N 1 ATOM 4155 C CA . SER A 1 513 ? 81.091 66.736 -18.701 1.00 17.20 ? 513 SER A CA 1 ATOM 4156 C C . SER A 1 513 ? 80.960 68.259 -18.643 1.00 16.92 ? 513 SER A C 1 ATOM 4157 O O . SER A 1 513 ? 81.908 68.936 -18.245 1.00 17.61 ? 513 SER A O 1 ATOM 4158 C CB . SER A 1 513 ? 82.240 66.351 -19.632 1.00 17.92 ? 513 SER A CB 1 ATOM 4159 O OG . SER A 1 513 ? 81.908 66.681 -20.946 1.00 18.63 ? 513 SER A OG 1 ATOM 4160 N N . ILE A 1 514 ? 79.801 68.794 -19.054 1.00 16.13 ? 514 ILE A N 1 ATOM 4161 C CA . ILE A 1 514 ? 79.516 70.234 -19.029 1.00 17.25 ? 514 ILE A CA 1 ATOM 4162 C C . ILE A 1 514 ? 78.538 70.584 -17.880 1.00 15.14 ? 514 ILE A C 1 ATOM 4163 O O . ILE A 1 514 ? 78.562 71.666 -17.307 1.00 15.49 ? 514 ILE A O 1 ATOM 4164 C CB . ILE A 1 514 ? 78.911 70.687 -20.400 1.00 17.35 ? 514 ILE A CB 1 ATOM 4165 C CG1 . ILE A 1 514 ? 79.954 70.558 -21.514 1.00 20.35 ? 514 ILE A CG1 1 ATOM 4166 C CG2 . ILE A 1 514 ? 78.344 72.122 -20.315 1.00 19.05 ? 514 ILE A CG2 1 ATOM 4167 C CD1 . ILE A 1 514 ? 79.448 70.858 -22.910 1.00 20.47 ? 514 ILE A CD1 1 ATOM 4168 N N . TYR A 1 515 ? 77.663 69.635 -17.559 1.00 14.73 ? 515 TYR A N 1 ATOM 4169 C CA . TYR A 1 515 ? 76.626 69.845 -16.543 1.00 14.40 ? 515 TYR A CA 1 ATOM 4170 C C . TYR A 1 515 ? 77.198 70.403 -15.234 1.00 13.90 ? 515 TYR A C 1 ATOM 4171 O O . TYR A 1 515 ? 78.085 69.773 -14.591 1.00 13.99 ? 515 TYR A O 1 ATOM 4172 C CB . TYR A 1 515 ? 75.939 68.513 -16.346 1.00 14.88 ? 515 TYR A CB 1 ATOM 4173 C CG . TYR A 1 515 ? 74.919 68.479 -15.265 1.00 14.08 ? 515 TYR A CG 1 ATOM 4174 C CD1 . TYR A 1 515 ? 73.747 69.222 -15.346 1.00 12.55 ? 515 TYR A CD1 1 ATOM 4175 C CD2 . TYR A 1 515 ? 75.127 67.684 -14.158 1.00 14.77 ? 515 TYR A CD2 1 ATOM 4176 C CE1 . TYR A 1 515 ? 72.787 69.165 -14.336 1.00 13.25 ? 515 TYR A CE1 1 ATOM 4177 C CE2 . TYR A 1 515 ? 74.184 67.609 -13.146 1.00 13.28 ? 515 TYR A CE2 1 ATOM 4178 C CZ . TYR A 1 515 ? 73.027 68.364 -13.246 1.00 14.44 ? 515 TYR A CZ 1 ATOM 4179 O OH . TYR A 1 515 ? 72.103 68.282 -12.250 1.00 13.94 ? 515 TYR A OH 1 ATOM 4180 N N . SER A 1 516 ? 76.729 71.587 -14.832 1.00 14.64 ? 516 SER A N 1 ATOM 4181 C CA . SER A 1 516 ? 77.259 72.290 -13.659 1.00 15.26 ? 516 SER A CA 1 ATOM 4182 C C . SER A 1 516 ? 76.121 72.943 -12.842 1.00 15.66 ? 516 SER A C 1 ATOM 4183 O O . SER A 1 516 ? 75.937 74.169 -12.864 1.00 16.16 ? 516 SER A O 1 ATOM 4184 C CB . SER A 1 516 ? 78.317 73.323 -14.101 1.00 16.20 ? 516 SER A CB 1 ATOM 4185 O OG . SER A 1 516 ? 78.993 73.818 -12.956 1.00 19.51 ? 516 SER A OG 1 ATOM 4186 N N . PRO A 1 517 ? 75.332 72.120 -12.150 1.00 16.38 ? 517 PRO A N 1 ATOM 4187 C CA . PRO A 1 517 ? 74.084 72.621 -11.580 1.00 16.68 ? 517 PRO A CA 1 ATOM 4188 C C . PRO A 1 517 ? 74.227 73.502 -10.356 1.00 16.63 ? 517 PRO A C 1 ATOM 4189 O O . PRO A 1 517 ? 75.081 73.232 -9.489 1.00 19.36 ? 517 PRO A O 1 ATOM 4190 C CB . PRO A 1 517 ? 73.319 71.339 -11.211 1.00 17.19 ? 517 PRO A CB 1 ATOM 4191 C CG . PRO A 1 517 ? 74.399 70.363 -10.903 1.00 16.50 ? 517 PRO A CG 1 ATOM 4192 C CD . PRO A 1 517 ? 75.514 70.685 -11.901 1.00 16.54 ? 517 PRO A CD 1 ATOM 4193 N N . ASP A 1 518 ? 73.440 74.567 -10.318 1.00 17.30 ? 518 ASP A N 1 ATOM 4194 C CA . ASP A 1 518 ? 73.136 75.300 -9.112 1.00 17.36 ? 518 ASP A CA 1 ATOM 4195 C C . ASP A 1 518 ? 71.715 74.843 -8.773 1.00 16.26 ? 518 ASP A C 1 ATOM 4196 O O . ASP A 1 518 ? 70.774 75.128 -9.513 1.00 15.76 ? 518 ASP A O 1 ATOM 4197 C CB . ASP A 1 518 ? 73.188 76.790 -9.424 1.00 18.56 ? 518 ASP A CB 1 ATOM 4198 C CG . ASP A 1 518 ? 72.667 77.661 -8.305 1.00 21.30 ? 518 ASP A CG 1 ATOM 4199 O OD1 . ASP A 1 518 ? 72.082 77.154 -7.314 1.00 20.58 ? 518 ASP A OD1 1 ATOM 4200 O OD2 . ASP A 1 518 ? 72.768 78.906 -8.375 1.00 23.71 ? 518 ASP A OD2 1 ATOM 4201 N N . PHE A 1 519 ? 71.575 74.149 -7.653 1.00 16.01 ? 519 PHE A N 1 ATOM 4202 C CA . PHE A 1 519 ? 70.292 73.509 -7.333 1.00 15.85 ? 519 PHE A CA 1 ATOM 4203 C C . PHE A 1 519 ? 69.193 74.485 -6.930 1.00 16.77 ? 519 PHE A C 1 ATOM 4204 O O . PHE A 1 519 ? 68.041 74.074 -6.764 1.00 17.91 ? 519 PHE A O 1 ATOM 4205 C CB . PHE A 1 519 ? 70.492 72.429 -6.281 1.00 15.76 ? 519 PHE A CB 1 ATOM 4206 C CG . PHE A 1 519 ? 71.358 71.283 -6.728 1.00 15.52 ? 519 PHE A CG 1 ATOM 4207 C CD1 . PHE A 1 519 ? 71.081 70.578 -7.911 1.00 16.02 ? 519 PHE A CD1 1 ATOM 4208 C CD2 . PHE A 1 519 ? 72.438 70.890 -5.951 1.00 17.81 ? 519 PHE A CD2 1 ATOM 4209 C CE1 . PHE A 1 519 ? 71.871 69.527 -8.317 1.00 16.75 ? 519 PHE A CE1 1 ATOM 4210 C CE2 . PHE A 1 519 ? 73.238 69.841 -6.346 1.00 17.28 ? 519 PHE A CE2 1 ATOM 4211 C CZ . PHE A 1 519 ? 72.951 69.133 -7.527 1.00 17.90 ? 519 PHE A CZ 1 ATOM 4212 N N . SER A 1 520 ? 69.528 75.763 -6.785 1.00 16.57 ? 520 SER A N 1 ATOM 4213 C CA . SER A 1 520 ? 68.561 76.811 -6.487 1.00 18.26 ? 520 SER A CA 1 ATOM 4214 C C . SER A 1 520 ? 68.131 77.602 -7.747 1.00 17.52 ? 520 SER A C 1 ATOM 4215 O O . SER A 1 520 ? 67.168 78.369 -7.700 1.00 18.43 ? 520 SER A O 1 ATOM 4216 C CB . SER A 1 520 ? 69.145 77.773 -5.438 1.00 18.79 ? 520 SER A CB 1 ATOM 4217 O OG . SER A 1 520 ? 70.061 78.689 -6.017 1.00 23.20 ? 520 SER A OG 1 ATOM 4218 N N . PHE A 1 521 ? 68.829 77.387 -8.870 1.00 16.81 ? 521 PHE A N 1 ATOM 4219 C CA . PHE A 1 521 ? 68.637 78.195 -10.079 1.00 16.66 ? 521 PHE A CA 1 ATOM 4220 C C . PHE A 1 521 ? 67.512 77.661 -10.979 1.00 15.82 ? 521 PHE A C 1 ATOM 4221 O O . PHE A 1 521 ? 67.305 76.445 -11.043 1.00 15.98 ? 521 PHE A O 1 ATOM 4222 C CB . PHE A 1 521 ? 69.950 78.202 -10.865 1.00 17.86 ? 521 PHE A CB 1 ATOM 4223 C CG . PHE A 1 521 ? 69.951 79.152 -12.025 1.00 18.83 ? 521 PHE A CG 1 ATOM 4224 C CD1 . PHE A 1 521 ? 70.094 80.526 -11.823 1.00 22.78 ? 521 PHE A CD1 1 ATOM 4225 C CD2 . PHE A 1 521 ? 69.818 78.680 -13.328 1.00 19.91 ? 521 PHE A CD2 1 ATOM 4226 C CE1 . PHE A 1 521 ? 70.083 81.414 -12.913 1.00 25.14 ? 521 PHE A CE1 1 ATOM 4227 C CE2 . PHE A 1 521 ? 69.800 79.558 -14.417 1.00 21.41 ? 521 PHE A CE2 1 ATOM 4228 C CZ . PHE A 1 521 ? 69.944 80.923 -14.209 1.00 22.69 ? 521 PHE A CZ 1 ATOM 4229 N N . SER A 1 522 ? 66.824 78.567 -11.674 1.00 15.93 ? 522 SER A N 1 ATOM 4230 C CA . SER A 1 522 ? 65.796 78.209 -12.643 1.00 16.45 ? 522 SER A CA 1 ATOM 4231 C C . SER A 1 522 ? 66.398 78.134 -14.043 1.00 14.60 ? 522 SER A C 1 ATOM 4232 O O . SER A 1 522 ? 66.510 79.153 -14.721 1.00 16.40 ? 522 SER A O 1 ATOM 4233 C CB . SER A 1 522 ? 64.676 79.252 -12.637 1.00 18.26 ? 522 SER A CB 1 ATOM 4234 O OG . SER A 1 522 ? 63.949 79.149 -11.422 1.00 25.05 ? 522 SER A OG 1 ATOM 4235 N N . TYR A 1 523 ? 66.777 76.938 -14.465 1.00 12.29 ? 523 TYR A N 1 ATOM 4236 C CA . TYR A 1 523 ? 67.248 76.714 -15.840 1.00 11.54 ? 523 TYR A CA 1 ATOM 4237 C C . TYR A 1 523 ? 66.122 76.803 -16.861 1.00 11.31 ? 523 TYR A C 1 ATOM 4238 O O . TYR A 1 523 ? 66.337 77.230 -18.003 1.00 10.85 ? 523 TYR A O 1 ATOM 4239 C CB . TYR A 1 523 ? 67.937 75.350 -15.955 1.00 11.94 ? 523 TYR A CB 1 ATOM 4240 C CG . TYR A 1 523 ? 69.214 75.335 -15.158 1.00 12.87 ? 523 TYR A CG 1 ATOM 4241 C CD1 . TYR A 1 523 ? 70.388 75.926 -15.670 1.00 14.51 ? 523 TYR A CD1 1 ATOM 4242 C CD2 . TYR A 1 523 ? 69.244 74.789 -13.878 1.00 13.88 ? 523 TYR A CD2 1 ATOM 4243 C CE1 . TYR A 1 523 ? 71.559 75.948 -14.910 1.00 16.15 ? 523 TYR A CE1 1 ATOM 4244 C CE2 . TYR A 1 523 ? 70.416 74.792 -13.126 1.00 15.02 ? 523 TYR A CE2 1 ATOM 4245 C CZ . TYR A 1 523 ? 71.545 75.392 -13.642 1.00 16.22 ? 523 TYR A CZ 1 ATOM 4246 O OH . TYR A 1 523 ? 72.688 75.399 -12.881 1.00 17.05 ? 523 TYR A OH 1 ATOM 4247 N N . PHE A 1 524 ? 64.918 76.391 -16.449 1.00 10.63 ? 524 PHE A N 1 ATOM 4248 C CA . PHE A 1 524 ? 63.726 76.437 -17.289 1.00 9.96 ? 524 PHE A CA 1 ATOM 4249 C C . PHE A 1 524 ? 62.583 76.923 -16.456 1.00 11.48 ? 524 PHE A C 1 ATOM 4250 O O . PHE A 1 524 ? 62.547 76.684 -15.245 1.00 11.90 ? 524 PHE A O 1 ATOM 4251 C CB . PHE A 1 524 ? 63.352 75.049 -17.832 1.00 9.96 ? 524 PHE A CB 1 ATOM 4252 C CG . PHE A 1 524 ? 64.397 74.427 -18.712 1.00 9.40 ? 524 PHE A CG 1 ATOM 4253 C CD1 . PHE A 1 524 ? 65.402 73.654 -18.125 1.00 10.75 ? 524 PHE A CD1 1 ATOM 4254 C CD2 . PHE A 1 524 ? 64.351 74.542 -20.109 1.00 10.68 ? 524 PHE A CD2 1 ATOM 4255 C CE1 . PHE A 1 524 ? 66.361 73.056 -18.892 1.00 11.04 ? 524 PHE A CE1 1 ATOM 4256 C CE2 . PHE A 1 524 ? 65.303 73.922 -20.901 1.00 10.35 ? 524 PHE A CE2 1 ATOM 4257 C CZ . PHE A 1 524 ? 66.323 73.181 -20.275 1.00 11.20 ? 524 PHE A CZ 1 ATOM 4258 N N . THR A 1 525 ? 61.648 77.567 -17.120 1.00 11.91 ? 525 THR A N 1 ATOM 4259 C CA . THR A 1 525 ? 60.343 77.764 -16.492 1.00 13.30 ? 525 THR A CA 1 ATOM 4260 C C . THR A 1 525 ? 59.294 76.966 -17.252 1.00 12.64 ? 525 THR A C 1 ATOM 4261 O O . THR A 1 525 ? 59.361 76.821 -18.486 1.00 13.01 ? 525 THR A O 1 ATOM 4262 C CB . THR A 1 525 ? 59.946 79.227 -16.476 1.00 15.54 ? 525 THR A CB 1 ATOM 4263 O OG1 . THR A 1 525 ? 59.855 79.687 -17.805 1.00 18.28 ? 525 THR A OG1 1 ATOM 4264 C CG2 . THR A 1 525 ? 61.051 80.141 -15.865 1.00 17.76 ? 525 THR A CG2 1 ATOM 4265 N N . LEU A 1 526 ? 58.313 76.464 -16.521 1.00 11.65 ? 526 LEU A N 1 ATOM 4266 C CA . LEU A 1 526 ? 57.207 75.762 -17.154 1.00 13.03 ? 526 LEU A CA 1 ATOM 4267 C C . LEU A 1 526 ? 56.277 76.765 -17.819 1.00 12.87 ? 526 LEU A C 1 ATOM 4268 O O . LEU A 1 526 ? 56.008 77.848 -17.282 1.00 15.21 ? 526 LEU A O 1 ATOM 4269 C CB . LEU A 1 526 ? 56.400 74.938 -16.141 1.00 14.52 ? 526 LEU A CB 1 ATOM 4270 C CG . LEU A 1 526 ? 56.944 73.578 -15.725 1.00 17.03 ? 526 LEU A CG 1 ATOM 4271 C CD1 . LEU A 1 526 ? 56.137 73.114 -14.501 1.00 19.00 ? 526 LEU A CD1 1 ATOM 4272 C CD2 . LEU A 1 526 ? 56.815 72.590 -16.873 1.00 18.08 ? 526 LEU A CD2 1 ATOM 4273 N N . ASP A 1 527 ? 55.720 76.369 -18.949 1.00 10.34 ? 527 ASP A N 1 ATOM 4274 C CA . ASP A 1 527 ? 54.715 77.149 -19.647 1.00 12.58 ? 527 ASP A CA 1 ATOM 4275 C C . ASP A 1 527 ? 53.487 76.267 -19.700 1.00 11.71 ? 527 ASP A C 1 ATOM 4276 O O . ASP A 1 527 ? 53.541 75.167 -20.212 1.00 14.12 ? 527 ASP A O 1 ATOM 4277 C CB . ASP A 1 527 ? 55.189 77.525 -21.069 1.00 12.09 ? 527 ASP A CB 1 ATOM 4278 C CG . ASP A 1 527 ? 54.161 78.350 -21.814 1.00 15.43 ? 527 ASP A CG 1 ATOM 4279 O OD1 . ASP A 1 527 ? 53.885 79.484 -21.386 1.00 17.57 ? 527 ASP A OD1 1 ATOM 4280 O OD2 . ASP A 1 527 ? 53.562 77.926 -22.829 1.00 19.28 ? 527 ASP A OD2 1 ATOM 4281 N N . ASP A 1 528 ? 52.389 76.737 -19.124 1.00 11.49 ? 528 ASP A N 1 ATOM 4282 C CA . ASP A 1 528 ? 51.177 75.930 -19.128 1.00 12.13 ? 528 ASP A CA 1 ATOM 4283 C C . ASP A 1 528 ? 50.065 76.772 -19.745 1.00 12.27 ? 528 ASP A C 1 ATOM 4284 O O . ASP A 1 528 ? 49.711 77.811 -19.204 1.00 12.75 ? 528 ASP A O 1 ATOM 4285 C CB . ASP A 1 528 ? 50.844 75.524 -17.692 1.00 11.94 ? 528 ASP A CB 1 ATOM 4286 C CG . ASP A 1 528 ? 49.785 74.470 -17.621 1.00 12.65 ? 528 ASP A CG 1 ATOM 4287 O OD1 . ASP A 1 528 ? 48.763 74.542 -18.331 1.00 12.38 ? 528 ASP A OD1 1 ATOM 4288 O OD2 . ASP A 1 528 ? 49.936 73.494 -16.852 1.00 13.37 ? 528 ASP A OD2 1 ATOM 4289 N N . SER A 1 529 ? 49.517 76.301 -20.857 1.00 13.28 ? 529 SER A N 1 ATOM 4290 C CA . SER A 1 529 ? 48.487 77.030 -21.600 1.00 14.30 ? 529 SER A CA 1 ATOM 4291 C C . SER A 1 529 ? 47.107 76.893 -21.019 1.00 14.31 ? 529 SER A C 1 ATOM 4292 O O . SER A 1 529 ? 46.203 77.596 -21.454 1.00 16.64 ? 529 SER A O 1 ATOM 4293 C CB . SER A 1 529 ? 48.375 76.542 -23.051 1.00 16.23 ? 529 SER A CB 1 ATOM 4294 O OG . SER A 1 529 ? 49.604 76.564 -23.713 1.00 21.14 ? 529 SER A OG 1 ATOM 4295 N N . ARG A 1 530 ? 46.901 75.976 -20.080 1.00 12.63 ? 530 ARG A N 1 ATOM 4296 C CA . ARG A 1 530 ? 45.546 75.704 -19.602 1.00 13.06 ? 530 ARG A CA 1 ATOM 4297 C C . ARG A 1 530 ? 45.392 75.781 -18.120 1.00 13.25 ? 530 ARG A C 1 ATOM 4298 O O . ARG A 1 530 ? 44.354 75.358 -17.591 1.00 15.97 ? 530 ARG A O 1 ATOM 4299 C CB . ARG A 1 530 ? 45.072 74.322 -20.077 1.00 13.04 ? 530 ARG A CB 1 ATOM 4300 C CG . ARG A 1 530 ? 45.014 74.248 -21.612 1.00 14.06 ? 530 ARG A CG 1 ATOM 4301 C CD . ARG A 1 530 ? 44.348 73.016 -22.199 1.00 13.18 ? 530 ARG A CD 1 ATOM 4302 N NE . ARG A 1 530 ? 45.028 71.821 -21.713 1.00 14.36 ? 530 ARG A NE 1 ATOM 4303 C CZ . ARG A 1 530 ? 44.849 70.610 -22.222 1.00 15.81 ? 530 ARG A CZ 1 ATOM 4304 N NH1 . ARG A 1 530 ? 44.006 70.408 -23.236 1.00 19.76 ? 530 ARG A NH1 1 ATOM 4305 N NH2 . ARG A 1 530 ? 45.509 69.609 -21.701 1.00 15.37 ? 530 ARG A NH2 1 ATOM 4306 N N . TRP A 1 531 ? 46.410 76.259 -17.422 1.00 10.68 ? 531 TRP A N 1 ATOM 4307 C CA . TRP A 1 531 ? 46.267 76.484 -15.983 1.00 11.08 ? 531 TRP A CA 1 ATOM 4308 C C . TRP A 1 531 ? 47.192 77.620 -15.550 1.00 11.63 ? 531 TRP A C 1 ATOM 4309 O O . TRP A 1 531 ? 48.392 77.534 -15.811 1.00 12.42 ? 531 TRP A O 1 ATOM 4310 C CB . TRP A 1 531 ? 46.619 75.230 -15.141 1.00 12.54 ? 531 TRP A CB 1 ATOM 4311 C CG . TRP A 1 531 ? 46.515 75.590 -13.686 1.00 13.38 ? 531 TRP A CG 1 ATOM 4312 C CD1 . TRP A 1 531 ? 47.551 76.026 -12.859 1.00 15.37 ? 531 TRP A CD1 1 ATOM 4313 C CD2 . TRP A 1 531 ? 45.332 75.689 -12.936 1.00 14.49 ? 531 TRP A CD2 1 ATOM 4314 N NE1 . TRP A 1 531 ? 47.049 76.335 -11.621 1.00 18.06 ? 531 TRP A NE1 1 ATOM 4315 C CE2 . TRP A 1 531 ? 45.692 76.148 -11.631 1.00 12.91 ? 531 TRP A CE2 1 ATOM 4316 C CE3 . TRP A 1 531 ? 44.011 75.413 -13.209 1.00 14.21 ? 531 TRP A CE3 1 ATOM 4317 C CZ2 . TRP A 1 531 ? 44.738 76.338 -10.598 1.00 15.67 ? 531 TRP A CZ2 1 ATOM 4318 C CZ3 . TRP A 1 531 ? 43.067 75.608 -12.204 1.00 15.03 ? 531 TRP A CZ3 1 ATOM 4319 C CH2 . TRP A 1 531 ? 43.440 76.061 -10.908 1.00 15.29 ? 531 TRP A CH2 1 ATOM 4320 N N . PRO A 1 532 ? 46.690 78.608 -14.809 1.00 12.01 ? 532 PRO A N 1 ATOM 4321 C CA . PRO A 1 532 ? 45.266 78.796 -14.455 1.00 12.61 ? 532 PRO A CA 1 ATOM 4322 C C . PRO A 1 532 ? 44.389 79.105 -15.654 1.00 13.28 ? 532 PRO A C 1 ATOM 4323 O O . PRO A 1 532 ? 43.165 78.969 -15.581 1.00 14.44 ? 532 PRO A O 1 ATOM 4324 C CB . PRO A 1 532 ? 45.324 80.013 -13.498 1.00 12.98 ? 532 PRO A CB 1 ATOM 4325 C CG . PRO A 1 532 ? 46.708 79.910 -12.901 1.00 15.61 ? 532 PRO A CG 1 ATOM 4326 C CD . PRO A 1 532 ? 47.557 79.597 -14.124 1.00 12.68 ? 532 PRO A CD 1 ATOM 4327 N N . GLY A 1 533 ? 45.005 79.484 -16.764 1.00 14.38 ? 533 GLY A N 1 ATOM 4328 C CA . GLY A 1 533 ? 44.260 79.714 -17.981 1.00 17.36 ? 533 GLY A CA 1 ATOM 4329 C C . GLY A 1 533 ? 44.146 81.154 -18.376 1.00 20.01 ? 533 GLY A C 1 ATOM 4330 O O . GLY A 1 533 ? 44.227 82.071 -17.534 1.00 19.15 ? 533 GLY A O 1 ATOM 4331 N N . SER A 1 534 ? 43.975 81.315 -19.691 1.00 22.36 ? 534 SER A N 1 ATOM 4332 C CA . SER A 1 534 ? 43.713 82.601 -20.313 1.00 24.61 ? 534 SER A CA 1 ATOM 4333 C C . SER A 1 534 ? 42.445 83.156 -19.704 1.00 24.44 ? 534 SER A C 1 ATOM 4334 O O . SER A 1 534 ? 41.398 82.474 -19.659 1.00 24.64 ? 534 SER A O 1 ATOM 4335 C CB . SER A 1 534 ? 43.542 82.443 -21.827 1.00 25.81 ? 534 SER A CB 1 ATOM 4336 O OG . SER A 1 534 ? 43.372 83.705 -22.448 1.00 30.37 ? 534 SER A OG 1 ATOM 4337 N N . GLY A 1 535 ? 42.536 84.384 -19.218 1.00 24.37 ? 535 GLY A N 1 ATOM 4338 C CA . GLY A 1 535 ? 41.390 85.016 -18.599 1.00 23.88 ? 535 GLY A CA 1 ATOM 4339 C C . GLY A 1 535 ? 41.243 84.705 -17.125 1.00 23.85 ? 535 GLY A C 1 ATOM 4340 O O . GLY A 1 535 ? 40.362 85.247 -16.450 1.00 24.50 ? 535 GLY A O 1 ATOM 4341 N N . VAL A 1 536 ? 42.087 83.811 -16.609 1.00 23.02 ? 536 VAL A N 1 ATOM 4342 C CA . VAL A 1 536 ? 42.059 83.501 -15.184 1.00 23.26 ? 536 VAL A CA 1 ATOM 4343 C C . VAL A 1 536 ? 43.222 84.206 -14.493 1.00 24.71 ? 536 VAL A C 1 ATOM 4344 O O . VAL A 1 536 ? 43.020 84.958 -13.538 1.00 24.03 ? 536 VAL A O 1 ATOM 4345 C CB . VAL A 1 536 ? 42.088 81.977 -14.917 1.00 22.84 ? 536 VAL A CB 1 ATOM 4346 C CG1 . VAL A 1 536 ? 41.951 81.688 -13.422 1.00 22.73 ? 536 VAL A CG1 1 ATOM 4347 C CG2 . VAL A 1 536 ? 40.949 81.285 -15.673 1.00 23.06 ? 536 VAL A CG2 1 ATOM 4348 N N . GLU A 1 537 ? 44.433 83.966 -14.985 1.00 25.48 ? 537 GLU A N 1 ATOM 4349 C CA . GLU A 1 537 ? 45.631 84.633 -14.480 1.00 27.47 ? 537 GLU A CA 1 ATOM 4350 C C . GLU A 1 537 ? 46.547 84.923 -15.656 1.00 28.16 ? 537 GLU A C 1 ATOM 4351 O O . GLU A 1 537 ? 46.735 84.069 -16.531 1.00 28.21 ? 537 GLU A O 1 ATOM 4352 C CB . GLU A 1 537 ? 46.345 83.729 -13.485 1.00 27.83 ? 537 GLU A CB 1 ATOM 4353 C CG . GLU A 1 537 ? 47.639 84.272 -12.899 1.00 31.47 ? 537 GLU A CG 1 ATOM 4354 C CD . GLU A 1 537 ? 48.141 83.407 -11.762 1.00 35.11 ? 537 GLU A CD 1 ATOM 4355 O OE1 . GLU A 1 537 ? 47.433 83.316 -10.729 1.00 36.79 ? 537 GLU A OE1 1 ATOM 4356 O OE2 . GLU A 1 537 ? 49.237 82.808 -11.895 1.00 37.46 ? 537 GLU A OE2 1 ATOM 4357 N N . ASP A 1 538 ? 47.117 86.124 -15.675 1.00 29.16 ? 538 ASP A N 1 ATOM 4358 C CA . ASP A 1 538 ? 48.161 86.434 -16.645 1.00 30.72 ? 538 ASP A CA 1 ATOM 4359 C C . ASP A 1 538 ? 49.462 85.889 -16.049 1.00 30.25 ? 538 ASP A C 1 ATOM 4360 O O . ASP A 1 538 ? 50.145 86.566 -15.278 1.00 31.17 ? 538 ASP A O 1 ATOM 4361 C CB . ASP A 1 538 ? 48.227 87.952 -16.883 1.00 31.67 ? 538 ASP A CB 1 ATOM 4362 C CG . ASP A 1 538 ? 48.735 88.302 -18.265 1.00 34.74 ? 538 ASP A CG 1 ATOM 4363 O OD1 . ASP A 1 538 ? 49.826 87.812 -18.637 1.00 37.89 ? 538 ASP A OD1 1 ATOM 4364 O OD2 . ASP A 1 538 ? 48.120 89.064 -19.056 1.00 38.87 ? 538 ASP A OD2 1 ATOM 4365 N N . SER A 1 539 ? 49.781 84.637 -16.361 1.00 29.01 ? 539 SER A N 1 ATOM 4366 C CA . SER A 1 539 ? 50.914 83.974 -15.709 1.00 28.47 ? 539 SER A CA 1 ATOM 4367 C C . SER A 1 539 ? 52.004 83.559 -16.694 1.00 27.25 ? 539 SER A C 1 ATOM 4368 O O . SER A 1 539 ? 53.153 83.356 -16.293 1.00 28.32 ? 539 SER A O 1 ATOM 4369 C CB . SER A 1 539 ? 50.452 82.759 -14.889 1.00 28.40 ? 539 SER A CB 1 ATOM 4370 O OG . SER A 1 539 ? 49.902 81.750 -15.726 1.00 30.73 ? 539 SER A OG 1 ATOM 4371 N N . ARG A 1 540 ? 51.635 83.431 -17.970 1.00 25.14 ? 540 ARG A N 1 ATOM 4372 C CA . ARG A 1 540 ? 52.539 82.899 -18.987 1.00 23.18 ? 540 ARG A CA 1 ATOM 4373 C C . ARG A 1 540 ? 53.622 83.886 -19.333 1.00 22.41 ? 540 ARG A C 1 ATOM 4374 O O . ARG A 1 540 ? 53.354 85.076 -19.455 1.00 22.99 ? 540 ARG A O 1 ATOM 4375 C CB . ARG A 1 540 ? 51.755 82.516 -20.229 1.00 22.62 ? 540 ARG A CB 1 ATOM 4376 C CG . ARG A 1 540 ? 50.946 81.242 -19.987 1.00 20.28 ? 540 ARG A CG 1 ATOM 4377 C CD . ARG A 1 540 ? 50.195 80.786 -21.177 1.00 17.81 ? 540 ARG A CD 1 ATOM 4378 N NE . ARG A 1 540 ? 51.084 80.136 -22.132 1.00 15.97 ? 540 ARG A NE 1 ATOM 4379 C CZ . ARG A 1 540 ? 50.684 79.733 -23.326 1.00 17.72 ? 540 ARG A CZ 1 ATOM 4380 N NH1 . ARG A 1 540 ? 49.425 79.917 -23.719 1.00 16.96 ? 540 ARG A NH1 1 ATOM 4381 N NH2 . ARG A 1 540 ? 51.536 79.138 -24.125 1.00 17.38 ? 540 ARG A NH2 1 ATOM 4382 N N . THR A 1 541 ? 54.847 83.390 -19.469 1.00 21.65 ? 541 THR A N 1 ATOM 4383 C CA . THR A 1 541 ? 55.919 84.263 -19.903 1.00 21.20 ? 541 THR A CA 1 ATOM 4384 C C . THR A 1 541 ? 55.953 84.300 -21.422 1.00 19.51 ? 541 THR A C 1 ATOM 4385 O O . THR A 1 541 ? 55.711 83.301 -22.102 1.00 21.54 ? 541 THR A O 1 ATOM 4386 C CB . THR A 1 541 ? 57.277 83.819 -19.367 1.00 22.35 ? 541 THR A CB 1 ATOM 4387 O OG1 . THR A 1 541 ? 57.675 82.641 -20.051 1.00 24.85 ? 541 THR A OG1 1 ATOM 4388 C CG2 . THR A 1 541 ? 57.197 83.381 -17.907 1.00 21.68 ? 541 THR A CG2 1 ATOM 4389 N N . THR A 1 542 ? 56.240 85.481 -21.938 1.00 17.05 ? 542 THR A N 1 ATOM 4390 C CA . THR A 1 542 ? 56.495 85.661 -23.355 1.00 15.47 ? 542 THR A CA 1 ATOM 4391 C C . THR A 1 542 ? 57.967 85.393 -23.635 1.00 14.08 ? 542 THR A C 1 ATOM 4392 O O . THR A 1 542 ? 58.861 85.862 -22.893 1.00 14.90 ? 542 THR A O 1 ATOM 4393 C CB . THR A 1 542 ? 56.193 87.099 -23.708 1.00 15.90 ? 542 THR A CB 1 ATOM 4394 O OG1 . THR A 1 542 ? 54.827 87.373 -23.381 1.00 17.81 ? 542 THR A OG1 1 ATOM 4395 C CG2 . THR A 1 542 ? 56.314 87.350 -25.206 1.00 16.40 ? 542 THR A CG2 1 ATOM 4396 N N . ILE A 1 543 ? 58.229 84.650 -24.700 1.00 12.75 ? 543 ILE A N 1 ATOM 4397 C CA . ILE A 1 543 ? 59.584 84.469 -25.185 1.00 12.49 ? 543 ILE A CA 1 ATOM 4398 C C . ILE A 1 543 ? 59.943 85.736 -25.965 1.00 12.82 ? 543 ILE A C 1 ATOM 4399 O O . ILE A 1 543 ? 59.317 86.058 -26.987 1.00 12.79 ? 543 ILE A O 1 ATOM 4400 C CB . ILE A 1 543 ? 59.677 83.221 -26.056 1.00 12.06 ? 543 ILE A CB 1 ATOM 4401 C CG1 . ILE A 1 543 ? 59.360 81.952 -25.199 1.00 12.27 ? 543 ILE A CG1 1 ATOM 4402 C CG2 . ILE A 1 543 ? 61.055 83.171 -26.750 1.00 12.61 ? 543 ILE A CG2 1 ATOM 4403 C CD1 . ILE A 1 543 ? 59.313 80.666 -25.966 1.00 12.77 ? 543 ILE A CD1 1 ATOM 4404 N N . ILE A 1 544 ? 60.897 86.471 -25.407 1.00 13.30 ? 544 ILE A N 1 ATOM 4405 C CA . ILE A 1 544 ? 61.278 87.775 -25.963 1.00 14.67 ? 544 ILE A CA 1 ATOM 4406 C C . ILE A 1 544 ? 62.505 87.613 -26.847 1.00 14.09 ? 544 ILE A C 1 ATOM 4407 O O . ILE A 1 544 ? 63.607 87.273 -26.389 1.00 14.15 ? 544 ILE A O 1 ATOM 4408 C CB . ILE A 1 544 ? 61.501 88.784 -24.830 1.00 15.25 ? 544 ILE A CB 1 ATOM 4409 C CG1 . ILE A 1 544 ? 60.185 89.004 -24.068 1.00 18.03 ? 544 ILE A CG1 1 ATOM 4410 C CG2 . ILE A 1 544 ? 62.014 90.112 -25.378 1.00 17.72 ? 544 ILE A CG2 1 ATOM 4411 C CD1 . ILE A 1 544 ? 60.271 90.004 -22.906 1.00 19.30 ? 544 ILE A CD1 1 ATOM 4412 N N . LEU A 1 545 ? 62.244 87.777 -28.134 1.00 13.87 ? 545 LEU A N 1 ATOM 4413 C CA . LEU A 1 545 ? 63.265 87.677 -29.164 1.00 14.05 ? 545 LEU A CA 1 ATOM 4414 C C . LEU A 1 545 ? 63.401 89.028 -29.858 1.00 15.11 ? 545 LEU A C 1 ATOM 4415 O O . LEU A 1 545 ? 62.458 89.816 -29.902 1.00 16.00 ? 545 LEU A O 1 ATOM 4416 C CB . LEU A 1 545 ? 62.886 86.595 -30.194 1.00 14.03 ? 545 LEU A CB 1 ATOM 4417 C CG . LEU A 1 545 ? 62.700 85.162 -29.659 1.00 14.94 ? 545 LEU A CG 1 ATOM 4418 C CD1 . LEU A 1 545 ? 62.291 84.199 -30.758 1.00 16.29 ? 545 LEU A CD1 1 ATOM 4419 C CD2 . LEU A 1 545 ? 63.957 84.652 -28.993 1.00 14.54 ? 545 LEU A CD2 1 ATOM 4420 N N . GLY A 1 546 ? 64.563 89.276 -30.438 1.00 15.65 ? 546 GLY A N 1 ATOM 4421 C CA . GLY A 1 546 ? 64.786 90.534 -31.125 1.00 16.47 ? 546 GLY A CA 1 ATOM 4422 C C . GLY A 1 546 ? 66.208 90.590 -31.604 1.00 16.27 ? 546 GLY A C 1 ATOM 4423 O O . GLY A 1 546 ? 67.125 90.086 -30.939 1.00 14.58 ? 546 GLY A O 1 ATOM 4424 N N . GLU A 1 547 ? 66.398 91.251 -32.738 1.00 17.82 ? 547 GLU A N 1 ATOM 4425 C CA . GLU A 1 547 ? 67.724 91.367 -33.348 1.00 20.28 ? 547 GLU A CA 1 ATOM 4426 C C . GLU A 1 547 ? 68.749 92.009 -32.413 1.00 20.19 ? 547 GLU A C 1 ATOM 4427 O O . GLU A 1 547 ? 69.931 91.668 -32.446 1.00 21.66 ? 547 GLU A O 1 ATOM 4428 C CB . GLU A 1 547 ? 67.623 92.189 -34.627 1.00 21.74 ? 547 GLU A CB 1 ATOM 4429 C CG . GLU A 1 547 ? 68.931 92.272 -35.404 1.00 27.98 ? 547 GLU A CG 1 ATOM 4430 C CD . GLU A 1 547 ? 68.849 93.216 -36.589 1.00 33.45 ? 547 GLU A CD 1 ATOM 4431 O OE1 . GLU A 1 547 ? 67.717 93.522 -37.035 1.00 37.29 ? 547 GLU A OE1 1 ATOM 4432 O OE2 . GLU A 1 547 ? 69.918 93.655 -37.078 1.00 37.10 ? 547 GLU A OE2 1 ATOM 4433 N N . ASP A 1 548 ? 68.284 92.936 -31.579 1.00 19.46 ? 548 ASP A N 1 ATOM 4434 C CA . ASP A 1 548 ? 69.174 93.650 -30.662 1.00 20.04 ? 548 ASP A CA 1 ATOM 4435 C C . ASP A 1 548 ? 69.154 93.082 -29.249 1.00 20.25 ? 548 ASP A C 1 ATOM 4436 O O . ASP A 1 548 ? 69.651 93.719 -28.309 1.00 21.61 ? 548 ASP A O 1 ATOM 4437 C CB . ASP A 1 548 ? 68.810 95.134 -30.624 1.00 20.39 ? 548 ASP A CB 1 ATOM 4438 C CG . ASP A 1 548 ? 69.016 95.817 -31.949 1.00 22.09 ? 548 ASP A CG 1 ATOM 4439 O OD1 . ASP A 1 548 ? 70.179 95.934 -32.383 1.00 26.71 ? 548 ASP A OD1 1 ATOM 4440 O OD2 . ASP A 1 548 ? 68.076 96.282 -32.618 1.00 26.01 ? 548 ASP A OD2 1 ATOM 4441 N N . ILE A 1 549 ? 68.612 91.874 -29.085 1.00 18.84 ? 549 ILE A N 1 ATOM 4442 C CA . ILE A 1 549 ? 68.592 91.262 -27.748 1.00 19.01 ? 549 ILE A CA 1 ATOM 4443 C C . ILE A 1 549 ? 68.871 89.762 -27.746 1.00 17.84 ? 549 ILE A C 1 ATOM 4444 O O . ILE A 1 549 ? 69.702 89.304 -26.964 1.00 18.39 ? 549 ILE A O 1 ATOM 4445 C CB . ILE A 1 549 ? 67.297 91.608 -26.942 1.00 18.42 ? 549 ILE A CB 1 ATOM 4446 C CG1 . ILE A 1 549 ? 67.425 91.113 -25.480 1.00 20.41 ? 549 ILE A CG1 1 ATOM 4447 C CG2 . ILE A 1 549 ? 66.012 91.145 -27.663 1.00 18.00 ? 549 ILE A CG2 1 ATOM 4448 C CD1 . ILE A 1 549 ? 66.263 91.444 -24.561 1.00 21.51 ? 549 ILE A CD1 1 ATOM 4449 N N . LEU A 1 550 ? 68.192 89.021 -28.605 1.00 16.55 ? 550 LEU A N 1 ATOM 4450 C CA . LEU A 1 550 ? 68.263 87.570 -28.542 1.00 15.46 ? 550 LEU A CA 1 ATOM 4451 C C . LEU A 1 550 ? 67.585 86.966 -29.745 1.00 14.99 ? 550 LEU A C 1 ATOM 4452 O O . LEU A 1 550 ? 66.404 87.141 -29.933 1.00 15.16 ? 550 LEU A O 1 ATOM 4453 C CB . LEU A 1 550 ? 67.586 87.067 -27.264 1.00 16.30 ? 550 LEU A CB 1 ATOM 4454 C CG . LEU A 1 550 ? 67.621 85.557 -27.024 1.00 16.22 ? 550 LEU A CG 1 ATOM 4455 C CD1 . LEU A 1 550 ? 69.043 85.094 -26.874 1.00 18.11 ? 550 LEU A CD1 1 ATOM 4456 C CD2 . LEU A 1 550 ? 66.793 85.193 -25.810 1.00 16.94 ? 550 LEU A CD2 1 ATOM 4457 N N . PRO A 1 551 ? 68.330 86.248 -30.563 1.00 14.89 ? 551 PRO A N 1 ATOM 4458 C CA . PRO A 1 551 ? 67.756 85.790 -31.824 1.00 15.21 ? 551 PRO A CA 1 ATOM 4459 C C . PRO A 1 551 ? 66.905 84.531 -31.687 1.00 14.06 ? 551 PRO A C 1 ATOM 4460 O O . PRO A 1 551 ? 66.034 84.319 -32.503 1.00 14.51 ? 551 PRO A O 1 ATOM 4461 C CB . PRO A 1 551 ? 68.977 85.513 -32.710 1.00 15.90 ? 551 PRO A CB 1 ATOM 4462 C CG . PRO A 1 551 ? 70.115 85.554 -31.871 1.00 18.29 ? 551 PRO A CG 1 ATOM 4463 C CD . PRO A 1 551 ? 69.800 86.290 -30.615 1.00 16.01 ? 551 PRO A CD 1 ATOM 4464 N N . SER A 1 552 ? 67.187 83.702 -30.689 1.00 13.26 ? 552 SER A N 1 ATOM 4465 C CA . SER A 1 552 ? 66.541 82.403 -30.602 1.00 12.55 ? 552 SER A CA 1 ATOM 4466 C C . SER A 1 552 ? 66.402 81.913 -29.166 1.00 11.69 ? 552 SER A C 1 ATOM 4467 O O . SER A 1 552 ? 67.056 82.408 -28.275 1.00 11.69 ? 552 SER A O 1 ATOM 4468 C CB . SER A 1 552 ? 67.297 81.373 -31.431 1.00 14.44 ? 552 SER A CB 1 ATOM 4469 O OG . SER A 1 552 ? 68.528 81.040 -30.839 1.00 16.41 ? 552 SER A OG 1 ATOM 4470 N N . LYS A 1 553 ? 65.528 80.929 -28.986 1.00 10.85 ? 553 LYS A N 1 ATOM 4471 C CA . LYS A 1 553 ? 65.241 80.334 -27.676 1.00 10.52 ? 553 LYS A CA 1 ATOM 4472 C C . LYS A 1 553 ? 64.983 78.820 -27.823 1.00 9.51 ? 553 LYS A C 1 ATOM 4473 O O . LYS A 1 553 ? 64.192 78.391 -28.662 1.00 10.51 ? 553 LYS A O 1 ATOM 4474 C CB . LYS A 1 553 ? 63.968 80.988 -27.106 1.00 11.09 ? 553 LYS A CB 1 ATOM 4475 C CG . LYS A 1 553 ? 63.475 80.392 -25.768 1.00 12.86 ? 553 LYS A CG 1 ATOM 4476 C CD . LYS A 1 553 ? 64.505 80.534 -24.690 1.00 13.44 ? 553 LYS A CD 1 ATOM 4477 C CE . LYS A 1 553 ? 64.725 82.004 -24.260 1.00 15.63 ? 553 LYS A CE 1 ATOM 4478 N NZ . LYS A 1 553 ? 65.926 82.121 -23.337 1.00 15.04 ? 553 LYS A NZ 1 ATOM 4479 N N . HIS A 1 554 ? 65.642 78.040 -26.965 1.00 10.37 ? 554 HIS A N 1 ATOM 4480 C CA . HIS A 1 554 ? 65.330 76.619 -26.812 1.00 9.88 ? 554 HIS A CA 1 ATOM 4481 C C . HIS A 1 554 ? 64.117 76.391 -25.895 1.00 9.26 ? 554 HIS A C 1 ATOM 4482 O O . HIS A 1 554 ? 63.978 77.029 -24.833 1.00 10.10 ? 554 HIS A O 1 ATOM 4483 C CB . HIS A 1 554 ? 66.540 75.936 -26.181 1.00 12.04 ? 554 HIS A CB 1 ATOM 4484 C CG . HIS A 1 554 ? 67.689 75.709 -27.120 1.00 14.02 ? 554 HIS A CG 1 ATOM 4485 N ND1 . HIS A 1 554 ? 68.230 76.712 -27.908 1.00 19.90 ? 554 HIS A ND1 1 ATOM 4486 C CD2 . HIS A 1 554 ? 68.387 74.591 -27.414 1.00 17.94 ? 554 HIS A CD2 1 ATOM 4487 C CE1 . HIS A 1 554 ? 69.238 76.222 -28.608 1.00 21.37 ? 554 HIS A CE1 1 ATOM 4488 N NE2 . HIS A 1 554 ? 69.361 74.941 -28.316 1.00 17.61 ? 554 HIS A NE2 1 ATOM 4489 N N . VAL A 1 555 ? 63.265 75.473 -26.346 1.00 9.03 ? 555 VAL A N 1 ATOM 4490 C CA . VAL A 1 555 ? 62.137 74.970 -25.552 1.00 9.26 ? 555 VAL A CA 1 ATOM 4491 C C . VAL A 1 555 ? 62.247 73.446 -25.548 1.00 9.03 ? 555 VAL A C 1 ATOM 4492 O O . VAL A 1 555 ? 62.756 72.838 -26.489 1.00 9.24 ? 555 VAL A O 1 ATOM 4493 C CB . VAL A 1 555 ? 60.782 75.464 -26.081 1.00 9.47 ? 555 VAL A CB 1 ATOM 4494 C CG1 . VAL A 1 555 ? 60.700 76.990 -26.028 1.00 9.95 ? 555 VAL A CG1 1 ATOM 4495 C CG2 . VAL A 1 555 ? 60.525 74.985 -27.481 1.00 10.08 ? 555 VAL A CG2 1 ATOM 4496 N N . VAL A 1 556 ? 61.732 72.820 -24.481 1.00 8.70 ? 556 VAL A N 1 ATOM 4497 C CA . VAL A 1 556 ? 61.780 71.365 -24.308 1.00 7.74 ? 556 VAL A CA 1 ATOM 4498 C C . VAL A 1 556 ? 60.378 70.890 -23.927 1.00 7.51 ? 556 VAL A C 1 ATOM 4499 O O . VAL A 1 556 ? 59.738 71.490 -23.045 1.00 7.83 ? 556 VAL A O 1 ATOM 4500 C CB . VAL A 1 556 ? 62.778 70.970 -23.216 1.00 8.17 ? 556 VAL A CB 1 ATOM 4501 C CG1 . VAL A 1 556 ? 62.710 69.475 -22.972 1.00 8.88 ? 556 VAL A CG1 1 ATOM 4502 C CG2 . VAL A 1 556 ? 64.188 71.411 -23.607 1.00 9.30 ? 556 VAL A CG2 1 ATOM 4503 N N . MET A 1 557 ? 59.947 69.814 -24.561 1.00 7.62 ? 557 MET A N 1 ATOM 4504 C CA . MET A 1 557 ? 58.709 69.130 -24.182 1.00 7.22 ? 557 MET A CA 1 ATOM 4505 C C . MET A 1 557 ? 58.991 67.807 -23.511 1.00 8.11 ? 557 MET A C 1 ATOM 4506 O O . MET A 1 557 ? 59.877 67.053 -23.928 1.00 8.43 ? 557 MET A O 1 ATOM 4507 C CB . MET A 1 557 ? 57.822 68.868 -25.415 1.00 8.00 ? 557 MET A CB 1 ATOM 4508 C CG . MET A 1 557 ? 56.811 69.991 -25.692 1.00 9.30 ? 557 MET A CG 1 ATOM 4509 S SD . MET A 1 557 ? 57.487 71.622 -25.930 1.00 10.69 ? 557 MET A SD 1 ATOM 4510 C CE . MET A 1 557 ? 58.536 71.359 -27.384 1.00 13.64 ? 557 MET A CE 1 ATOM 4511 N N . HIS A 1 558 ? 58.213 67.511 -22.458 1.00 7.85 ? 558 HIS A N 1 ATOM 4512 C CA . HIS A 1 558 ? 58.237 66.209 -21.789 1.00 7.02 ? 558 HIS A CA 1 ATOM 4513 C C . HIS A 1 558 ? 56.961 65.453 -22.024 1.00 7.52 ? 558 HIS A C 1 ATOM 4514 O O . HIS A 1 558 ? 55.881 66.037 -21.984 1.00 7.92 ? 558 HIS A O 1 ATOM 4515 C CB . HIS A 1 558 ? 58.423 66.394 -20.279 1.00 8.46 ? 558 HIS A CB 1 ATOM 4516 C CG . HIS A 1 558 ? 58.341 65.130 -19.497 1.00 7.66 ? 558 HIS A CG 1 ATOM 4517 N ND1 . HIS A 1 558 ? 57.418 64.945 -18.489 1.00 8.30 ? 558 HIS A ND1 1 ATOM 4518 C CD2 . HIS A 1 558 ? 59.104 64.014 -19.519 1.00 7.89 ? 558 HIS A CD2 1 ATOM 4519 C CE1 . HIS A 1 558 ? 57.605 63.750 -17.946 1.00 8.22 ? 558 HIS A CE1 1 ATOM 4520 N NE2 . HIS A 1 558 ? 58.625 63.164 -18.540 1.00 7.79 ? 558 HIS A NE2 1 ATOM 4521 N N . ASN A 1 559 ? 57.093 64.139 -22.242 1.00 7.13 ? 559 ASN A N 1 ATOM 4522 C CA . ASN A 1 559 ? 55.953 63.276 -22.426 1.00 6.85 ? 559 ASN A CA 1 ATOM 4523 C C . ASN A 1 559 ? 55.959 62.195 -21.356 1.00 7.33 ? 559 ASN A C 1 ATOM 4524 O O . ASN A 1 559 ? 56.747 61.257 -21.452 1.00 7.92 ? 559 ASN A O 1 ATOM 4525 C CB . ASN A 1 559 ? 56.067 62.625 -23.797 1.00 7.68 ? 559 ASN A CB 1 ATOM 4526 C CG . ASN A 1 559 ? 55.044 61.551 -24.019 1.00 7.92 ? 559 ASN A CG 1 ATOM 4527 O OD1 . ASN A 1 559 ? 53.958 61.544 -23.435 1.00 8.20 ? 559 ASN A OD1 1 ATOM 4528 N ND2 . ASN A 1 559 ? 55.375 60.614 -24.902 1.00 9.83 ? 559 ASN A ND2 1 ATOM 4529 N N . THR A 1 560 ? 55.083 62.300 -20.365 1.00 6.78 ? 560 THR A N 1 ATOM 4530 C CA . THR A 1 560 ? 55.103 61.322 -19.281 1.00 7.21 ? 560 THR A CA 1 ATOM 4531 C C . THR A 1 560 ? 54.519 59.967 -19.682 1.00 7.45 ? 560 THR A C 1 ATOM 4532 O O . THR A 1 560 ? 54.691 58.980 -18.955 1.00 8.38 ? 560 THR A O 1 ATOM 4533 C CB . THR A 1 560 ? 54.344 61.930 -18.091 1.00 6.91 ? 560 THR A CB 1 ATOM 4534 O OG1 . THR A 1 560 ? 54.617 61.170 -16.881 1.00 8.26 ? 560 THR A OG1 1 ATOM 4535 C CG2 . THR A 1 560 ? 52.840 61.953 -18.300 1.00 8.86 ? 560 THR A CG2 1 ATOM 4536 N N . LEU A 1 561 ? 53.801 59.888 -20.804 1.00 7.61 ? 561 LEU A N 1 ATOM 4537 C CA . LEU A 1 561 ? 53.180 58.635 -21.234 1.00 7.97 ? 561 LEU A CA 1 ATOM 4538 C C . LEU A 1 561 ? 54.185 57.716 -21.909 1.00 7.58 ? 561 LEU A C 1 ATOM 4539 O O . LEU A 1 561 ? 55.086 58.179 -22.594 1.00 8.08 ? 561 LEU A O 1 ATOM 4540 C CB . LEU A 1 561 ? 52.031 58.927 -22.216 1.00 8.52 ? 561 LEU A CB 1 ATOM 4541 C CG . LEU A 1 561 ? 50.897 59.821 -21.664 1.00 9.00 ? 561 LEU A CG 1 ATOM 4542 C CD1 . LEU A 1 561 ? 49.845 59.979 -22.764 1.00 12.26 ? 561 LEU A CD1 1 ATOM 4543 C CD2 . LEU A 1 561 ? 50.219 59.213 -20.428 1.00 9.72 ? 561 LEU A CD2 1 ATOM 4544 N N . PRO A 1 562 ? 54.019 56.404 -21.750 1.00 8.47 ? 562 PRO A N 1 ATOM 4545 C CA . PRO A 1 562 ? 54.992 55.449 -22.318 1.00 8.73 ? 562 PRO A CA 1 ATOM 4546 C C . PRO A 1 562 ? 54.759 55.080 -23.774 1.00 9.47 ? 562 PRO A C 1 ATOM 4547 O O . PRO A 1 562 ? 54.940 53.915 -24.137 1.00 10.85 ? 562 PRO A O 1 ATOM 4548 C CB . PRO A 1 562 ? 54.815 54.239 -21.401 1.00 9.27 ? 562 PRO A CB 1 ATOM 4549 C CG . PRO A 1 562 ? 53.337 54.249 -21.078 1.00 8.63 ? 562 PRO A CG 1 ATOM 4550 C CD . PRO A 1 562 ? 52.992 55.736 -20.912 1.00 9.13 ? 562 PRO A CD 1 ATOM 4551 N N . HIS A 1 563 ? 54.393 56.050 -24.596 1.00 9.47 ? 563 HIS A N 1 ATOM 4552 C CA . HIS A 1 563 ? 54.337 55.819 -26.038 1.00 9.93 ? 563 HIS A CA 1 ATOM 4553 C C . HIS A 1 563 ? 54.755 57.113 -26.695 1.00 10.49 ? 563 HIS A C 1 ATOM 4554 O O . HIS A 1 563 ? 54.596 58.193 -26.095 1.00 10.15 ? 563 HIS A O 1 ATOM 4555 C CB . HIS A 1 563 ? 52.938 55.340 -26.481 1.00 10.76 ? 563 HIS A CB 1 ATOM 4556 C CG . HIS A 1 563 ? 51.800 56.207 -26.026 1.00 11.35 ? 563 HIS A CG 1 ATOM 4557 N ND1 . HIS A 1 563 ? 51.001 55.877 -24.950 1.00 11.62 ? 563 HIS A ND1 1 ATOM 4558 C CD2 . HIS A 1 563 ? 51.294 57.363 -26.528 1.00 12.58 ? 563 HIS A CD2 1 ATOM 4559 C CE1 . HIS A 1 563 ? 50.056 56.797 -24.806 1.00 13.40 ? 563 HIS A CE1 1 ATOM 4560 N NE2 . HIS A 1 563 ? 50.219 57.718 -25.742 1.00 13.19 ? 563 HIS A NE2 1 ATOM 4561 N N . TRP A 1 564 ? 55.302 57.041 -27.914 1.00 10.86 ? 564 TRP A N 1 ATOM 4562 C CA . TRP A 1 564 ? 55.595 58.256 -28.704 1.00 10.74 ? 564 TRP A CA 1 ATOM 4563 C C . TRP A 1 564 ? 54.330 59.069 -28.822 1.00 11.73 ? 564 TRP A C 1 ATOM 4564 O O . TRP A 1 564 ? 53.222 58.550 -29.014 1.00 11.51 ? 564 TRP A O 1 ATOM 4565 C CB . TRP A 1 564 ? 56.057 57.916 -30.146 1.00 12.36 ? 564 TRP A CB 1 ATOM 4566 C CG . TRP A 1 564 ? 57.444 57.465 -30.199 1.00 10.95 ? 564 TRP A CG 1 ATOM 4567 C CD1 . TRP A 1 564 ? 57.892 56.169 -30.051 1.00 13.39 ? 564 TRP A CD1 1 ATOM 4568 C CD2 . TRP A 1 564 ? 58.619 58.282 -30.337 1.00 11.08 ? 564 TRP A CD2 1 ATOM 4569 N NE1 . TRP A 1 564 ? 59.264 56.144 -30.096 1.00 14.40 ? 564 TRP A NE1 1 ATOM 4570 C CE2 . TRP A 1 564 ? 59.741 57.420 -30.270 1.00 12.81 ? 564 TRP A CE2 1 ATOM 4571 C CE3 . TRP A 1 564 ? 58.843 59.660 -30.497 1.00 12.84 ? 564 TRP A CE3 1 ATOM 4572 C CZ2 . TRP A 1 564 ? 61.058 57.887 -30.380 1.00 13.89 ? 564 TRP A CZ2 1 ATOM 4573 C CZ3 . TRP A 1 564 ? 60.165 60.117 -30.604 1.00 13.95 ? 564 TRP A CZ3 1 ATOM 4574 C CH2 . TRP A 1 564 ? 61.240 59.237 -30.537 1.00 15.05 ? 564 TRP A CH2 1 ATOM 4575 N N . ARG A 1 565 ? 54.494 60.380 -28.674 1.00 11.78 ? 565 ARG A N 1 ATOM 4576 C CA . ARG A 1 565 ? 53.351 61.247 -28.788 1.00 13.21 ? 565 ARG A CA 1 ATOM 4577 C C . ARG A 1 565 ? 53.703 62.448 -29.644 1.00 12.56 ? 565 ARG A C 1 ATOM 4578 O O . ARG A 1 565 ? 54.770 63.031 -29.494 1.00 13.27 ? 565 ARG A O 1 ATOM 4579 C CB . ARG A 1 565 ? 52.916 61.704 -27.392 1.00 14.96 ? 565 ARG A CB 1 ATOM 4580 C CG . ARG A 1 565 ? 51.528 62.267 -27.347 1.00 18.60 ? 565 ARG A CG 1 ATOM 4581 C CD . ARG A 1 565 ? 50.749 61.915 -26.054 1.00 17.46 ? 565 ARG A CD 1 ATOM 4582 N NE . ARG A 1 565 ? 51.471 62.308 -24.842 1.00 16.72 ? 565 ARG A NE 1 ATOM 4583 C CZ . ARG A 1 565 ? 50.930 62.977 -23.810 1.00 12.84 ? 565 ARG A CZ 1 ATOM 4584 N NH1 . ARG A 1 565 ? 49.641 63.360 -23.810 1.00 13.48 ? 565 ARG A NH1 1 ATOM 4585 N NH2 . ARG A 1 565 ? 51.713 63.246 -22.779 1.00 12.11 ? 565 ARG A NH2 1 ATOM 4586 N N . GLU A 1 566 ? 52.793 62.774 -30.546 1.00 13.33 ? 566 GLU A N 1 ATOM 4587 C CA . GLU A 1 566 ? 52.772 64.065 -31.180 1.00 15.54 ? 566 GLU A CA 1 ATOM 4588 C C . GLU A 1 566 ? 51.596 64.855 -30.615 1.00 16.17 ? 566 GLU A C 1 ATOM 4589 O O . GLU A 1 566 ? 50.518 64.303 -30.334 1.00 17.30 ? 566 GLU A O 1 ATOM 4590 C CB . GLU A 1 566 ? 52.602 63.928 -32.673 1.00 17.49 ? 566 GLU A CB 1 ATOM 4591 C CG . GLU A 1 566 ? 53.769 63.298 -33.345 1.00 19.36 ? 566 GLU A CG 1 ATOM 4592 C CD . GLU A 1 566 ? 53.573 63.225 -34.848 1.00 26.42 ? 566 GLU A CD 1 ATOM 4593 O OE1 . GLU A 1 566 ? 52.434 62.955 -35.305 1.00 30.29 ? 566 GLU A OE1 1 ATOM 4594 O OE2 . GLU A 1 566 ? 54.560 63.458 -35.564 1.00 28.86 ? 566 GLU A OE2 1 ATOM 4595 N N . GLN A 1 567 ? 51.798 66.158 -30.453 1.00 14.16 ? 567 GLN A N 1 ATOM 4596 C CA . GLN A 1 567 ? 50.773 67.018 -29.885 1.00 14.10 ? 567 GLN A CA 1 ATOM 4597 C C . GLN A 1 567 ? 51.168 68.437 -30.308 1.00 12.45 ? 567 GLN A C 1 ATOM 4598 O O . GLN A 1 567 ? 52.343 68.810 -30.265 1.00 11.16 ? 567 GLN A O 1 ATOM 4599 C CB . GLN A 1 567 ? 50.719 66.908 -28.332 1.00 14.55 ? 567 GLN A CB 1 ATOM 4600 C CG . GLN A 1 567 ? 49.600 67.754 -27.640 1.00 15.17 ? 567 GLN A CG 1 ATOM 4601 C CD . GLN A 1 567 ? 49.957 68.233 -26.207 1.00 17.10 ? 567 GLN A CD 1 ATOM 4602 O OE1 . GLN A 1 567 ? 49.954 67.426 -25.235 1.00 13.34 ? 567 GLN A OE1 1 ATOM 4603 N NE2 . GLN A 1 567 ? 50.228 69.549 -26.061 1.00 17.98 ? 567 GLN A NE2 1 ATOM 4604 N N . LEU A 1 568 ? 50.176 69.221 -30.706 1.00 11.17 ? 568 LEU A N 1 ATOM 4605 C CA . LEU A 1 568 ? 50.437 70.663 -30.860 1.00 10.51 ? 568 LEU A CA 1 ATOM 4606 C C . LEU A 1 568 ? 50.750 71.299 -29.528 1.00 10.02 ? 568 LEU A C 1 ATOM 4607 O O . LEU A 1 568 ? 50.073 71.014 -28.508 1.00 11.19 ? 568 LEU A O 1 ATOM 4608 C CB . LEU A 1 568 ? 49.226 71.389 -31.479 1.00 11.86 ? 568 LEU A CB 1 ATOM 4609 C CG . LEU A 1 568 ? 48.885 71.022 -32.925 1.00 12.90 ? 568 LEU A CG 1 ATOM 4610 C CD1 . LEU A 1 568 ? 47.829 71.977 -33.451 1.00 15.54 ? 568 LEU A CD1 1 ATOM 4611 C CD2 . LEU A 1 568 ? 50.076 71.168 -33.827 1.00 15.59 ? 568 LEU A CD2 1 ATOM 4612 N N . VAL A 1 569 ? 51.740 72.159 -29.521 1.00 9.45 ? 569 VAL A N 1 ATOM 4613 C CA . VAL A 1 569 ? 52.125 72.945 -28.350 1.00 9.30 ? 569 VAL A CA 1 ATOM 4614 C C . VAL A 1 569 ? 52.179 74.406 -28.761 1.00 10.66 ? 569 VAL A C 1 ATOM 4615 O O . VAL A 1 569 ? 52.437 74.715 -29.934 1.00 11.99 ? 569 VAL A O 1 ATOM 4616 C CB . VAL A 1 569 ? 53.491 72.509 -27.766 1.00 9.77 ? 569 VAL A CB 1 ATOM 4617 C CG1 . VAL A 1 569 ? 53.385 71.100 -27.173 1.00 10.84 ? 569 VAL A CG1 1 ATOM 4618 C CG2 . VAL A 1 569 ? 54.604 72.569 -28.790 1.00 10.10 ? 569 VAL A CG2 1 ATOM 4619 N N . ASP A 1 570 ? 51.925 75.294 -27.816 1.00 9.82 ? 570 ASP A N 1 ATOM 4620 C CA . ASP A 1 570 ? 51.956 76.724 -28.125 1.00 11.33 ? 570 ASP A CA 1 ATOM 4621 C C . ASP A 1 570 ? 52.757 77.488 -27.109 1.00 11.15 ? 570 ASP A C 1 ATOM 4622 O O . ASP A 1 570 ? 52.834 77.102 -25.921 1.00 12.43 ? 570 ASP A O 1 ATOM 4623 C CB . ASP A 1 570 ? 50.548 77.305 -28.278 1.00 12.76 ? 570 ASP A CB 1 ATOM 4624 C CG . ASP A 1 570 ? 49.821 77.434 -26.970 1.00 18.24 ? 570 ASP A CG 1 ATOM 4625 O OD1 . ASP A 1 570 ? 49.563 76.397 -26.333 1.00 26.35 ? 570 ASP A OD1 1 ATOM 4626 O OD2 . ASP A 1 570 ? 49.446 78.532 -26.495 1.00 23.80 ? 570 ASP A OD2 1 ATOM 4627 N N . PHE A 1 571 ? 53.395 78.556 -27.577 1.00 10.22 ? 571 PHE A N 1 ATOM 4628 C CA . PHE A 1 571 ? 54.149 79.470 -26.725 1.00 10.08 ? 571 PHE A CA 1 ATOM 4629 C C . PHE A 1 571 ? 53.776 80.906 -27.097 1.00 9.38 ? 571 PHE A C 1 ATOM 4630 O O . PHE A 1 571 ? 53.399 81.169 -28.242 1.00 11.45 ? 571 PHE A O 1 ATOM 4631 C CB . PHE A 1 571 ? 55.658 79.300 -26.956 1.00 10.10 ? 571 PHE A CB 1 ATOM 4632 C CG . PHE A 1 571 ? 56.184 77.956 -26.526 1.00 9.33 ? 571 PHE A CG 1 ATOM 4633 C CD1 . PHE A 1 571 ? 56.159 76.887 -27.396 1.00 9.32 ? 571 PHE A CD1 1 ATOM 4634 C CD2 . PHE A 1 571 ? 56.657 77.776 -25.246 1.00 9.69 ? 571 PHE A CD2 1 ATOM 4635 C CE1 . PHE A 1 571 ? 56.591 75.624 -27.001 1.00 8.96 ? 571 PHE A CE1 1 ATOM 4636 C CE2 . PHE A 1 571 ? 57.095 76.523 -24.830 1.00 9.51 ? 571 PHE A CE2 1 ATOM 4637 C CZ . PHE A 1 571 ? 57.072 75.460 -25.709 1.00 10.10 ? 571 PHE A CZ 1 ATOM 4638 N N . TYR A 1 572 ? 53.921 81.824 -26.161 1.00 9.34 ? 572 TYR A N 1 ATOM 4639 C CA . TYR A 1 572 ? 53.800 83.247 -26.469 1.00 10.65 ? 572 TYR A CA 1 ATOM 4640 C C . TYR A 1 572 ? 55.172 83.748 -26.875 1.00 10.79 ? 572 TYR A C 1 ATOM 4641 O O . TYR A 1 572 ? 56.183 83.427 -26.220 1.00 10.39 ? 572 TYR A O 1 ATOM 4642 C CB . TYR A 1 572 ? 53.350 84.022 -25.231 1.00 11.85 ? 572 TYR A CB 1 ATOM 4643 C CG . TYR A 1 572 ? 51.888 83.879 -24.839 1.00 13.71 ? 572 TYR A CG 1 ATOM 4644 C CD1 . TYR A 1 572 ? 50.981 83.186 -25.628 1.00 14.85 ? 572 TYR A CD1 1 ATOM 4645 C CD2 . TYR A 1 572 ? 51.421 84.494 -23.673 1.00 18.25 ? 572 TYR A CD2 1 ATOM 4646 C CE1 . TYR A 1 572 ? 49.629 83.073 -25.240 1.00 16.44 ? 572 TYR A CE1 1 ATOM 4647 C CE2 . TYR A 1 572 ? 50.077 84.399 -23.301 1.00 19.14 ? 572 TYR A CE2 1 ATOM 4648 C CZ . TYR A 1 572 ? 49.209 83.703 -24.096 1.00 17.12 ? 572 TYR A CZ 1 ATOM 4649 O OH . TYR A 1 572 ? 47.873 83.597 -23.729 1.00 20.57 ? 572 TYR A OH 1 ATOM 4650 N N . VAL A 1 573 ? 55.205 84.556 -27.940 1.00 11.02 ? 573 VAL A N 1 ATOM 4651 C CA . VAL A 1 573 ? 56.450 85.131 -28.470 1.00 11.60 ? 573 VAL A CA 1 ATOM 4652 C C . VAL A 1 573 ? 56.233 86.615 -28.765 1.00 10.99 ? 573 VAL A C 1 ATOM 4653 O O . VAL A 1 573 ? 55.110 87.053 -29.028 1.00 12.18 ? 573 VAL A O 1 ATOM 4654 C CB . VAL A 1 573 ? 56.926 84.411 -29.746 1.00 12.15 ? 573 VAL A CB 1 ATOM 4655 C CG1 . VAL A 1 573 ? 57.521 83.043 -29.409 1.00 13.93 ? 573 VAL A CG1 1 ATOM 4656 C CG2 . VAL A 1 573 ? 55.812 84.272 -30.794 1.00 13.18 ? 573 VAL A CG2 1 ATOM 4657 N N . SER A 1 574 ? 57.317 87.382 -28.730 1.00 12.14 ? 574 SER A N 1 ATOM 4658 C CA . SER A 1 574 ? 57.222 88.846 -28.855 1.00 12.94 ? 574 SER A CA 1 ATOM 4659 C C . SER A 1 574 ? 57.188 89.328 -30.293 1.00 14.11 ? 574 SER A C 1 ATOM 4660 O O . SER A 1 574 ? 57.093 90.551 -30.529 1.00 16.27 ? 574 SER A O 1 ATOM 4661 C CB . SER A 1 574 ? 58.378 89.495 -28.121 1.00 13.33 ? 574 SER A CB 1 ATOM 4662 O OG . SER A 1 574 ? 59.616 89.135 -28.729 1.00 13.57 ? 574 SER A OG 1 ATOM 4663 N N . SER A 1 575 ? 57.238 88.413 -31.253 1.00 13.97 ? 575 SER A N 1 ATOM 4664 C CA . SER A 1 575 ? 57.142 88.759 -32.673 1.00 15.48 ? 575 SER A CA 1 ATOM 4665 C C . SER A 1 575 ? 56.356 87.697 -33.430 1.00 15.42 ? 575 SER A C 1 ATOM 4666 O O . SER A 1 575 ? 56.402 86.512 -33.065 1.00 14.63 ? 575 SER A O 1 ATOM 4667 C CB . SER A 1 575 ? 58.544 88.843 -33.272 1.00 16.18 ? 575 SER A CB 1 ATOM 4668 O OG . SER A 1 575 ? 58.541 88.859 -34.697 1.00 17.34 ? 575 SER A OG 1 ATOM 4669 N N . PRO A 1 576 ? 55.648 88.076 -34.485 1.00 15.33 ? 576 PRO A N 1 ATOM 4670 C CA . PRO A 1 576 ? 54.975 87.080 -35.313 1.00 15.51 ? 576 PRO A CA 1 ATOM 4671 C C . PRO A 1 576 ? 55.919 86.358 -36.280 1.00 14.87 ? 576 PRO A C 1 ATOM 4672 O O . PRO A 1 576 ? 55.546 85.362 -36.874 1.00 15.09 ? 576 PRO A O 1 ATOM 4673 C CB . PRO A 1 576 ? 53.908 87.892 -36.058 1.00 15.99 ? 576 PRO A CB 1 ATOM 4674 C CG . PRO A 1 576 ? 54.381 89.299 -36.026 1.00 17.71 ? 576 PRO A CG 1 ATOM 4675 C CD . PRO A 1 576 ? 55.395 89.465 -34.940 1.00 15.70 ? 576 PRO A CD 1 ATOM 4676 N N . PHE A 1 577 ? 57.133 86.878 -36.457 1.00 14.50 ? 577 PHE A N 1 ATOM 4677 C CA . PHE A 1 577 ? 58.045 86.348 -37.458 1.00 14.92 ? 577 PHE A CA 1 ATOM 4678 C C . PHE A 1 577 ? 59.017 85.385 -36.793 1.00 14.81 ? 577 PHE A C 1 ATOM 4679 O O . PHE A 1 577 ? 60.178 85.697 -36.531 1.00 15.65 ? 577 PHE A O 1 ATOM 4680 C CB . PHE A 1 577 ? 58.768 87.497 -38.184 1.00 16.01 ? 577 PHE A CB 1 ATOM 4681 C CG . PHE A 1 577 ? 57.820 88.515 -38.779 1.00 18.36 ? 577 PHE A CG 1 ATOM 4682 C CD1 . PHE A 1 577 ? 56.782 88.109 -39.595 1.00 18.17 ? 577 PHE A CD1 1 ATOM 4683 C CD2 . PHE A 1 577 ? 57.985 89.880 -38.521 1.00 21.74 ? 577 PHE A CD2 1 ATOM 4684 C CE1 . PHE A 1 577 ? 55.901 89.049 -40.175 1.00 20.62 ? 577 PHE A CE1 1 ATOM 4685 C CE2 . PHE A 1 577 ? 57.116 90.828 -39.085 1.00 23.20 ? 577 PHE A CE2 1 ATOM 4686 C CZ . PHE A 1 577 ? 56.080 90.406 -39.911 1.00 21.63 ? 577 PHE A CZ 1 ATOM 4687 N N . VAL A 1 578 ? 58.478 84.201 -36.481 1.00 13.74 ? 578 VAL A N 1 ATOM 4688 C CA . VAL A 1 578 ? 59.218 83.197 -35.725 1.00 13.93 ? 578 VAL A CA 1 ATOM 4689 C C . VAL A 1 578 ? 59.108 81.872 -36.445 1.00 14.01 ? 578 VAL A C 1 ATOM 4690 O O . VAL A 1 578 ? 58.050 81.500 -36.926 1.00 14.60 ? 578 VAL A O 1 ATOM 4691 C CB . VAL A 1 578 ? 58.689 83.095 -34.258 1.00 13.57 ? 578 VAL A CB 1 ATOM 4692 C CG1 . VAL A 1 578 ? 59.431 81.976 -33.493 1.00 14.47 ? 578 VAL A CG1 1 ATOM 4693 C CG2 . VAL A 1 578 ? 58.928 84.376 -33.533 1.00 13.82 ? 578 VAL A CG2 1 ATOM 4694 N N . SER A 1 579 ? 60.223 81.167 -36.517 1.00 14.42 ? 579 SER A N 1 ATOM 4695 C CA . SER A 1 579 ? 60.186 79.841 -37.090 1.00 15.24 ? 579 SER A CA 1 ATOM 4696 C C . SER A 1 579 ? 60.729 78.822 -36.104 1.00 13.34 ? 579 SER A C 1 ATOM 4697 O O . SER A 1 579 ? 61.474 79.155 -35.196 1.00 14.20 ? 579 SER A O 1 ATOM 4698 C CB . SER A 1 579 ? 60.902 79.776 -38.440 1.00 17.98 ? 579 SER A CB 1 ATOM 4699 O OG . SER A 1 579 ? 62.199 80.246 -38.289 1.00 21.67 ? 579 SER A OG 1 ATOM 4700 N N . VAL A 1 580 ? 60.357 77.576 -36.334 1.00 12.06 ? 580 VAL A N 1 ATOM 4701 C CA . VAL A 1 580 ? 60.683 76.492 -35.417 1.00 11.75 ? 580 VAL A CA 1 ATOM 4702 C C . VAL A 1 580 ? 61.564 75.472 -36.142 1.00 12.95 ? 580 VAL A C 1 ATOM 4703 O O . VAL A 1 580 ? 61.290 75.104 -37.307 1.00 13.50 ? 580 VAL A O 1 ATOM 4704 C CB . VAL A 1 580 ? 59.398 75.806 -34.910 1.00 11.52 ? 580 VAL A CB 1 ATOM 4705 C CG1 . VAL A 1 580 ? 59.738 74.736 -33.882 1.00 12.21 ? 580 VAL A CG1 1 ATOM 4706 C CG2 . VAL A 1 580 ? 58.454 76.843 -34.302 1.00 13.08 ? 580 VAL A CG2 1 ATOM 4707 N N . THR A 1 581 ? 62.585 74.998 -35.432 1.00 12.97 ? 581 THR A N 1 ATOM 4708 C CA . THR A 1 581 ? 63.413 73.871 -35.873 1.00 13.43 ? 581 THR A CA 1 ATOM 4709 C C . THR A 1 581 ? 63.543 72.848 -34.746 1.00 12.58 ? 581 THR A C 1 ATOM 4710 O O . THR A 1 581 ? 63.382 73.199 -33.555 1.00 12.97 ? 581 THR A O 1 ATOM 4711 C CB . THR A 1 581 ? 64.820 74.346 -36.282 1.00 14.37 ? 581 THR A CB 1 ATOM 4712 O OG1 . THR A 1 581 ? 65.327 75.293 -35.331 1.00 16.68 ? 581 THR A OG1 1 ATOM 4713 C CG2 . THR A 1 581 ? 64.759 75.179 -37.595 1.00 13.98 ? 581 THR A CG2 1 ATOM 4714 N N . ASP A 1 582 ? 63.822 71.599 -35.100 1.00 13.90 ? 582 ASP A N 1 ATOM 4715 C CA . ASP A 1 582 ? 64.254 70.617 -34.098 1.00 15.02 ? 582 ASP A CA 1 ATOM 4716 C C . ASP A 1 582 ? 65.764 70.755 -33.850 1.00 16.36 ? 582 ASP A C 1 ATOM 4717 O O . ASP A 1 582 ? 66.395 71.660 -34.382 1.00 16.50 ? 582 ASP A O 1 ATOM 4718 C CB . ASP A 1 582 ? 63.809 69.200 -34.451 1.00 16.71 ? 582 ASP A CB 1 ATOM 4719 C CG . ASP A 1 582 ? 64.470 68.644 -35.721 1.00 16.51 ? 582 ASP A CG 1 ATOM 4720 O OD1 . ASP A 1 582 ? 65.527 69.159 -36.159 1.00 15.99 ? 582 ASP A OD1 1 ATOM 4721 O OD2 . ASP A 1 582 ? 63.981 67.657 -36.312 1.00 19.71 ? 582 ASP A OD2 1 ATOM 4722 N N . LEU A 1 583 ? 66.365 69.917 -32.997 1.00 19.77 ? 583 LEU A N 1 ATOM 4723 C CA . LEU A 1 583 ? 67.777 70.204 -32.731 1.00 21.01 ? 583 LEU A CA 1 ATOM 4724 C C . LEU A 1 583 ? 68.715 69.690 -33.838 1.00 21.38 ? 583 LEU A C 1 ATOM 4725 O O . LEU A 1 583 ? 69.922 69.963 -33.787 1.00 23.61 ? 583 LEU A O 1 ATOM 4726 C CB . LEU A 1 583 ? 68.252 69.796 -31.318 1.00 21.57 ? 583 LEU A CB 1 ATOM 4727 C CG . LEU A 1 583 ? 69.194 70.817 -30.652 1.00 21.09 ? 583 LEU A CG 1 ATOM 4728 C CD1 . LEU A 1 583 ? 68.580 72.221 -30.621 1.00 24.93 ? 583 LEU A CD1 1 ATOM 4729 C CD2 . LEU A 1 583 ? 69.567 70.423 -29.225 1.00 22.12 ? 583 LEU A CD2 1 ATOM 4730 N N . ALA A 1 584 ? 68.158 69.001 -34.849 1.00 19.62 ? 584 ALA A N 1 ATOM 4731 C CA . ALA A 1 584 ? 68.948 68.716 -36.062 1.00 17.65 ? 584 ALA A CA 1 ATOM 4732 C C . ALA A 1 584 ? 68.740 69.809 -37.098 1.00 16.71 ? 584 ALA A C 1 ATOM 4733 O O . ALA A 1 584 ? 69.151 69.678 -38.265 1.00 15.56 ? 584 ALA A O 1 ATOM 4734 C CB . ALA A 1 584 ? 68.611 67.358 -36.646 1.00 17.33 ? 584 ALA A CB 1 ATOM 4735 N N . ASN A 1 585 ? 68.091 70.891 -36.688 1.00 15.30 ? 585 ASN A N 1 ATOM 4736 C CA . ASN A 1 585 ? 67.892 72.061 -37.540 1.00 16.19 ? 585 ASN A CA 1 ATOM 4737 C C . ASN A 1 585 ? 66.904 71.777 -38.686 1.00 16.48 ? 585 ASN A C 1 ATOM 4738 O O . ASN A 1 585 ? 66.854 72.516 -39.685 1.00 18.99 ? 585 ASN A O 1 ATOM 4739 C CB . ASN A 1 585 ? 69.253 72.635 -38.027 1.00 17.21 ? 585 ASN A CB 1 ATOM 4740 C CG . ASN A 1 585 ? 69.180 74.097 -38.413 1.00 21.22 ? 585 ASN A CG 1 ATOM 4741 O OD1 . ASN A 1 585 ? 68.483 74.912 -37.787 1.00 23.87 ? 585 ASN A OD1 1 ATOM 4742 N ND2 . ASN A 1 585 ? 69.924 74.450 -39.463 1.00 23.98 ? 585 ASN A ND2 1 ATOM 4743 N N . ASN A 1 586 ? 66.109 70.724 -38.556 1.00 15.50 ? 586 ASN A N 1 ATOM 4744 C CA . ASN A 1 586 ? 65.029 70.451 -39.517 1.00 16.61 ? 586 ASN A CA 1 ATOM 4745 C C . ASN A 1 586 ? 63.896 71.440 -39.263 1.00 16.65 ? 586 ASN A C 1 ATOM 4746 O O . ASN A 1 586 ? 63.452 71.585 -38.114 1.00 15.42 ? 586 ASN A O 1 ATOM 4747 C CB . ASN A 1 586 ? 64.444 69.049 -39.352 1.00 17.28 ? 586 ASN A CB 1 ATOM 4748 C CG . ASN A 1 586 ? 65.476 67.959 -39.463 1.00 17.89 ? 586 ASN A CG 1 ATOM 4749 O OD1 . ASN A 1 586 ? 66.343 67.996 -40.341 1.00 18.47 ? 586 ASN A OD1 1 ATOM 4750 N ND2 . ASN A 1 586 ? 65.385 66.965 -38.573 1.00 16.20 ? 586 ASN A ND2 1 ATOM 4751 N N . PRO A 1 587 ? 63.396 72.130 -40.287 1.00 16.64 ? 587 PRO A N 1 ATOM 4752 C CA . PRO A 1 587 ? 62.267 73.047 -40.072 1.00 16.56 ? 587 PRO A CA 1 ATOM 4753 C C . PRO A 1 587 ? 61.034 72.283 -39.602 1.00 15.58 ? 587 PRO A C 1 ATOM 4754 O O . PRO A 1 587 ? 60.839 71.119 -39.987 1.00 16.53 ? 587 PRO A O 1 ATOM 4755 C CB . PRO A 1 587 ? 62.013 73.655 -41.461 1.00 17.34 ? 587 PRO A CB 1 ATOM 4756 C CG . PRO A 1 587 ? 63.205 73.315 -42.291 1.00 19.64 ? 587 PRO A CG 1 ATOM 4757 C CD . PRO A 1 587 ? 63.820 72.072 -41.704 1.00 17.37 ? 587 PRO A CD 1 ATOM 4758 N N . VAL A 1 588 ? 60.213 72.941 -38.775 1.00 14.33 ? 588 VAL A N 1 ATOM 4759 C CA . VAL A 1 588 ? 58.986 72.353 -38.271 1.00 13.62 ? 588 VAL A CA 1 ATOM 4760 C C . VAL A 1 588 ? 57.880 73.320 -38.659 1.00 12.96 ? 588 VAL A C 1 ATOM 4761 O O . VAL A 1 588 ? 58.020 74.519 -38.408 1.00 14.17 ? 588 VAL A O 1 ATOM 4762 C CB . VAL A 1 588 ? 59.043 72.181 -36.719 1.00 14.25 ? 588 VAL A CB 1 ATOM 4763 C CG1 . VAL A 1 588 ? 57.704 71.725 -36.149 1.00 14.61 ? 588 VAL A CG1 1 ATOM 4764 C CG2 . VAL A 1 588 ? 60.156 71.174 -36.329 1.00 13.80 ? 588 VAL A CG2 1 ATOM 4765 N N . GLU A 1 589 ? 56.806 72.820 -39.260 1.00 12.87 ? 589 GLU A N 1 ATOM 4766 C CA . GLU A 1 589 ? 55.701 73.670 -39.666 1.00 14.03 ? 589 GLU A CA 1 ATOM 4767 C C . GLU A 1 589 ? 55.071 74.303 -38.437 1.00 13.53 ? 589 GLU A C 1 ATOM 4768 O O . GLU A 1 589 ? 54.863 73.621 -37.429 1.00 14.48 ? 589 GLU A O 1 ATOM 4769 C CB . GLU A 1 589 ? 54.645 72.847 -40.383 1.00 15.16 ? 589 GLU A CB 1 ATOM 4770 C CG . GLU A 1 589 ? 53.503 73.717 -40.851 1.00 21.46 ? 589 GLU A CG 1 ATOM 4771 C CD . GLU A 1 589 ? 52.452 72.996 -41.656 1.00 27.40 ? 589 GLU A CD 1 ATOM 4772 O OE1 . GLU A 1 589 ? 52.657 71.807 -41.972 1.00 31.22 ? 589 GLU A OE1 1 ATOM 4773 O OE2 . GLU A 1 589 ? 51.407 73.633 -41.964 1.00 30.43 ? 589 GLU A OE2 1 ATOM 4774 N N . ALA A 1 590 ? 54.781 75.595 -38.504 1.00 12.34 ? 590 ALA A N 1 ATOM 4775 C CA . ALA A 1 590 ? 54.249 76.317 -37.364 1.00 11.98 ? 590 ALA A CA 1 ATOM 4776 C C . ALA A 1 590 ? 53.125 77.232 -37.821 1.00 11.85 ? 590 ALA A C 1 ATOM 4777 O O . ALA A 1 590 ? 53.022 77.577 -39.025 1.00 12.45 ? 590 ALA A O 1 ATOM 4778 C CB . ALA A 1 590 ? 55.312 77.092 -36.656 1.00 12.54 ? 590 ALA A CB 1 ATOM 4779 N N . GLN A 1 591 ? 52.283 77.623 -36.890 1.00 11.68 ? 591 GLN A N 1 ATOM 4780 C CA . GLN A 1 591 ? 51.190 78.565 -37.134 1.00 10.97 ? 591 GLN A CA 1 ATOM 4781 C C . GLN A 1 591 ? 51.271 79.645 -36.092 1.00 11.93 ? 591 GLN A C 1 ATOM 4782 O O . GLN A 1 591 ? 51.448 79.345 -34.905 1.00 12.63 ? 591 GLN A O 1 ATOM 4783 C CB . GLN A 1 591 ? 49.814 77.867 -37.090 1.00 12.10 ? 591 GLN A CB 1 ATOM 4784 C CG . GLN A 1 591 ? 48.636 78.857 -37.042 1.00 11.94 ? 591 GLN A CG 1 ATOM 4785 C CD . GLN A 1 591 ? 47.320 78.145 -36.834 1.00 11.56 ? 591 GLN A CD 1 ATOM 4786 O OE1 . GLN A 1 591 ? 47.107 77.058 -37.402 1.00 13.13 ? 591 GLN A OE1 1 ATOM 4787 N NE2 . GLN A 1 591 ? 46.448 78.715 -36.034 1.00 12.29 ? 591 GLN A NE2 1 ATOM 4788 N N . VAL A 1 592 ? 51.140 80.906 -36.507 1.00 11.09 ? 592 VAL A N 1 ATOM 4789 C CA . VAL A 1 592 ? 51.075 82.011 -35.573 1.00 11.09 ? 592 VAL A CA 1 ATOM 4790 C C . VAL A 1 592 ? 49.664 82.571 -35.575 1.00 11.62 ? 592 VAL A C 1 ATOM 4791 O O . VAL A 1 592 ? 49.030 82.679 -36.635 1.00 11.80 ? 592 VAL A O 1 ATOM 4792 C CB . VAL A 1 592 ? 52.138 83.076 -35.913 1.00 11.42 ? 592 VAL A CB 1 ATOM 4793 C CG1 . VAL A 1 592 ? 51.907 84.353 -35.103 1.00 12.51 ? 592 VAL A CG1 1 ATOM 4794 C CG2 . VAL A 1 592 ? 53.520 82.516 -35.589 1.00 11.64 ? 592 VAL A CG2 1 ATOM 4795 N N . SER A 1 593 ? 49.153 82.842 -34.378 1.00 12.78 ? 593 SER A N 1 ATOM 4796 C CA . SER A 1 593 ? 47.820 83.405 -34.153 1.00 13.58 ? 593 SER A CA 1 ATOM 4797 C C . SER A 1 593 ? 47.966 84.562 -33.187 1.00 13.41 ? 593 SER A C 1 ATOM 4798 O O . SER A 1 593 ? 48.951 84.649 -32.438 1.00 14.77 ? 593 SER A O 1 ATOM 4799 C CB . SER A 1 593 ? 46.826 82.361 -33.550 1.00 14.53 ? 593 SER A CB 1 ATOM 4800 O OG . SER A 1 593 ? 46.638 81.198 -34.366 1.00 15.49 ? 593 SER A OG 1 ATOM 4801 N N . PRO A 1 594 ? 46.987 85.445 -33.147 1.00 12.51 ? 594 PRO A N 1 ATOM 4802 C CA . PRO A 1 594 ? 47.027 86.501 -32.131 1.00 12.25 ? 594 PRO A CA 1 ATOM 4803 C C . PRO A 1 594 ? 46.815 85.979 -30.713 1.00 12.63 ? 594 PRO A C 1 ATOM 4804 O O . PRO A 1 594 ? 46.379 84.834 -30.524 1.00 12.43 ? 594 PRO A O 1 ATOM 4805 C CB . PRO A 1 594 ? 45.864 87.431 -32.527 1.00 13.40 ? 594 PRO A CB 1 ATOM 4806 C CG . PRO A 1 594 ? 45.517 87.025 -33.956 1.00 12.65 ? 594 PRO A CG 1 ATOM 4807 C CD . PRO A 1 594 ? 45.793 85.559 -34.014 1.00 12.47 ? 594 PRO A CD 1 ATOM 4808 N N . VAL A 1 595 ? 47.120 86.811 -29.712 1.00 12.37 ? 595 VAL A N 1 ATOM 4809 C CA . VAL A 1 595 ? 46.736 86.518 -28.347 1.00 12.69 ? 595 VAL A CA 1 ATOM 4810 C C . VAL A 1 595 ? 45.469 87.300 -28.075 1.00 12.77 ? 595 VAL A C 1 ATOM 4811 O O . VAL A 1 595 ? 45.491 88.545 -28.035 1.00 13.67 ? 595 VAL A O 1 ATOM 4812 C CB . VAL A 1 595 ? 47.848 86.872 -27.318 1.00 13.34 ? 595 VAL A CB 1 ATOM 4813 C CG1 . VAL A 1 595 ? 47.315 86.657 -25.917 1.00 13.74 ? 595 VAL A CG1 1 ATOM 4814 C CG2 . VAL A 1 595 ? 49.114 86.043 -27.564 1.00 14.41 ? 595 VAL A CG2 1 ATOM 4815 N N . TRP A 1 596 ? 44.357 86.593 -27.888 1.00 13.20 ? 596 TRP A N 1 ATOM 4816 C CA . TRP A 1 596 ? 43.055 87.197 -27.696 1.00 14.25 ? 596 TRP A CA 1 ATOM 4817 C C . TRP A 1 596 ? 42.672 87.079 -26.241 1.00 15.97 ? 596 TRP A C 1 ATOM 4818 O O . TRP A 1 596 ? 42.815 86.012 -25.637 1.00 16.50 ? 596 TRP A O 1 ATOM 4819 C CB . TRP A 1 596 ? 42.026 86.438 -28.548 1.00 14.26 ? 596 TRP A CB 1 ATOM 4820 C CG . TRP A 1 596 ? 42.152 86.630 -30.009 1.00 12.94 ? 596 TRP A CG 1 ATOM 4821 C CD1 . TRP A 1 596 ? 42.529 85.694 -30.945 1.00 12.78 ? 596 TRP A CD1 1 ATOM 4822 C CD2 . TRP A 1 596 ? 41.852 87.817 -30.739 1.00 11.88 ? 596 TRP A CD2 1 ATOM 4823 N NE1 . TRP A 1 596 ? 42.490 86.246 -32.205 1.00 13.30 ? 596 TRP A NE1 1 ATOM 4824 C CE2 . TRP A 1 596 ? 42.069 87.546 -32.102 1.00 13.72 ? 596 TRP A CE2 1 ATOM 4825 C CE3 . TRP A 1 596 ? 41.401 89.102 -30.372 1.00 12.92 ? 596 TRP A CE3 1 ATOM 4826 C CZ2 . TRP A 1 596 ? 41.866 88.514 -33.102 1.00 14.41 ? 596 TRP A CZ2 1 ATOM 4827 C CZ3 . TRP A 1 596 ? 41.202 90.060 -31.369 1.00 14.54 ? 596 TRP A CZ3 1 ATOM 4828 C CH2 . TRP A 1 596 ? 41.438 89.762 -32.703 1.00 14.42 ? 596 TRP A CH2 1 ATOM 4829 N N . SER A 1 597 ? 42.202 88.174 -25.665 1.00 15.99 ? 597 SER A N 1 ATOM 4830 C CA . SER A 1 597 ? 41.622 88.136 -24.332 1.00 17.31 ? 597 SER A CA 1 ATOM 4831 C C . SER A 1 597 ? 40.240 88.752 -24.375 1.00 16.65 ? 597 SER A C 1 ATOM 4832 O O . SER A 1 597 ? 39.962 89.645 -25.174 1.00 18.36 ? 597 SER A O 1 ATOM 4833 C CB . SER A 1 597 ? 42.486 88.885 -23.333 1.00 18.90 ? 597 SER A CB 1 ATOM 4834 O OG . SER A 1 597 ? 42.653 90.193 -23.796 1.00 21.79 ? 597 SER A OG 1 ATOM 4835 N N . TRP A 1 598 ? 39.392 88.286 -23.483 1.00 16.18 ? 598 TRP A N 1 ATOM 4836 C CA . TRP A 1 598 ? 38.011 88.728 -23.459 1.00 16.26 ? 598 TRP A CA 1 ATOM 4837 C C . TRP A 1 598 ? 37.764 89.655 -22.282 1.00 18.05 ? 598 TRP A C 1 ATOM 4838 O O . TRP A 1 598 ? 38.249 89.422 -21.183 1.00 19.46 ? 598 TRP A O 1 ATOM 4839 C CB . TRP A 1 598 ? 37.082 87.513 -23.386 1.00 15.61 ? 598 TRP A CB 1 ATOM 4840 C CG . TRP A 1 598 ? 37.033 86.761 -24.692 1.00 12.35 ? 598 TRP A CG 1 ATOM 4841 C CD1 . TRP A 1 598 ? 37.955 85.865 -25.168 1.00 12.64 ? 598 TRP A CD1 1 ATOM 4842 C CD2 . TRP A 1 598 ? 36.008 86.838 -25.691 1.00 12.24 ? 598 TRP A CD2 1 ATOM 4843 N NE1 . TRP A 1 598 ? 37.566 85.386 -26.392 1.00 12.02 ? 598 TRP A NE1 1 ATOM 4844 C CE2 . TRP A 1 598 ? 36.370 85.957 -26.736 1.00 11.09 ? 598 TRP A CE2 1 ATOM 4845 C CE3 . TRP A 1 598 ? 34.814 87.558 -25.805 1.00 12.93 ? 598 TRP A CE3 1 ATOM 4846 C CZ2 . TRP A 1 598 ? 35.584 85.788 -27.881 1.00 12.35 ? 598 TRP A CZ2 1 ATOM 4847 C CZ3 . TRP A 1 598 ? 34.028 87.380 -26.939 1.00 11.63 ? 598 TRP A CZ3 1 ATOM 4848 C CH2 . TRP A 1 598 ? 34.413 86.495 -27.955 1.00 13.33 ? 598 TRP A CH2 1 ATOM 4849 N N . HIS A 1 599 ? 36.970 90.677 -22.524 1.00 20.81 ? 599 HIS A N 1 ATOM 4850 C CA . HIS A 1 599 ? 36.773 91.752 -21.574 1.00 23.73 ? 599 HIS A CA 1 ATOM 4851 C C . HIS A 1 599 ? 35.290 92.016 -21.455 1.00 24.94 ? 599 HIS A C 1 ATOM 4852 O O . HIS A 1 599 ? 34.612 92.132 -22.458 1.00 23.80 ? 599 HIS A O 1 ATOM 4853 C CB . HIS A 1 599 ? 37.501 93.000 -22.061 1.00 25.24 ? 599 HIS A CB 1 ATOM 4854 C CG . HIS A 1 599 ? 38.983 92.830 -22.084 1.00 29.05 ? 599 HIS A CG 1 ATOM 4855 N ND1 . HIS A 1 599 ? 39.706 92.527 -20.954 1.00 33.47 ? 599 HIS A ND1 1 ATOM 4856 C CD2 . HIS A 1 599 ? 39.870 92.863 -23.102 1.00 32.37 ? 599 HIS A CD2 1 ATOM 4857 C CE1 . HIS A 1 599 ? 40.978 92.395 -21.273 1.00 32.88 ? 599 HIS A CE1 1 ATOM 4858 N NE2 . HIS A 1 599 ? 41.104 92.594 -22.570 1.00 34.61 ? 599 HIS A NE2 1 ATOM 4859 N N . HIS A 1 600 ? 34.783 92.102 -20.230 1.00 27.55 ? 600 HIS A N 1 ATOM 4860 C CA . HIS A 1 600 ? 33.442 92.630 -20.066 1.00 30.27 ? 600 HIS A CA 1 ATOM 4861 C C . HIS A 1 600 ? 33.605 94.123 -20.050 1.00 30.91 ? 600 HIS A C 1 ATOM 4862 O O . HIS A 1 600 ? 34.128 94.699 -19.087 1.00 31.85 ? 600 HIS A O 1 ATOM 4863 C CB . HIS A 1 600 ? 32.713 92.163 -18.806 1.00 30.92 ? 600 HIS A CB 1 ATOM 4864 C CG . HIS A 1 600 ? 31.421 92.892 -18.586 1.00 34.66 ? 600 HIS A CG 1 ATOM 4865 N ND1 . HIS A 1 600 ? 30.360 92.803 -19.464 1.00 37.14 ? 600 HIS A ND1 1 ATOM 4866 C CD2 . HIS A 1 600 ? 31.038 93.768 -17.626 1.00 37.26 ? 600 HIS A CD2 1 ATOM 4867 C CE1 . HIS A 1 600 ? 29.368 93.563 -19.038 1.00 38.22 ? 600 HIS A CE1 1 ATOM 4868 N NE2 . HIS A 1 600 ? 29.752 94.161 -17.923 1.00 38.74 ? 600 HIS A NE2 1 ATOM 4869 N N . ASP A 1 601 ? 33.183 94.733 -21.147 1.00 31.74 ? 601 ASP A N 1 ATOM 4870 C CA . ASP A 1 601 ? 33.298 96.156 -21.342 1.00 32.85 ? 601 ASP A CA 1 ATOM 4871 C C . ASP A 1 601 ? 32.153 96.836 -20.580 1.00 33.35 ? 601 ASP A C 1 ATOM 4872 O O . ASP A 1 601 ? 31.006 96.775 -21.016 1.00 33.10 ? 601 ASP A O 1 ATOM 4873 C CB . ASP A 1 601 ? 33.199 96.440 -22.835 1.00 33.06 ? 601 ASP A CB 1 ATOM 4874 C CG . ASP A 1 601 ? 33.563 97.859 -23.187 1.00 35.11 ? 601 ASP A CG 1 ATOM 4875 O OD1 . ASP A 1 601 ? 33.548 98.730 -22.282 1.00 35.17 ? 601 ASP A OD1 1 ATOM 4876 O OD2 . ASP A 1 601 ? 33.865 98.198 -24.356 1.00 37.44 ? 601 ASP A OD2 1 ATOM 4877 N N . THR A 1 602 ? 32.466 97.459 -19.442 1.00 34.21 ? 602 THR A N 1 ATOM 4878 C CA . THR A 1 602 ? 31.436 98.127 -18.628 1.00 35.46 ? 602 THR A CA 1 ATOM 4879 C C . THR A 1 602 ? 30.906 99.414 -19.258 1.00 35.19 ? 602 THR A C 1 ATOM 4880 O O . THR A 1 602 ? 29.892 99.952 -18.799 1.00 36.20 ? 602 THR A O 1 ATOM 4881 C CB . THR A 1 602 ? 31.905 98.381 -17.159 1.00 35.59 ? 602 THR A CB 1 ATOM 4882 O OG1 . THR A 1 602 ? 33.191 99.020 -17.150 1.00 37.91 ? 602 THR A OG1 1 ATOM 4883 C CG2 . THR A 1 602 ? 32.136 97.060 -16.422 1.00 36.54 ? 602 THR A CG2 1 ATOM 4884 N N . LEU A 1 603 ? 31.576 99.897 -20.306 1.00 34.35 ? 603 LEU A N 1 ATOM 4885 C CA . LEU A 1 603 ? 31.089 101.023 -21.095 1.00 33.60 ? 603 LEU A CA 1 ATOM 4886 C C . LEU A 1 603 ? 29.936 100.605 -22.000 1.00 32.35 ? 603 LEU A C 1 ATOM 4887 O O . LEU A 1 603 ? 28.813 101.087 -21.827 1.00 32.38 ? 603 LEU A O 1 ATOM 4888 C CB . LEU A 1 603 ? 32.219 101.662 -21.926 1.00 34.42 ? 603 LEU A CB 1 ATOM 4889 C CG . LEU A 1 603 ? 33.251 102.589 -21.255 1.00 35.60 ? 603 LEU A CG 1 ATOM 4890 C CD1 . LEU A 1 603 ? 32.563 103.719 -20.478 1.00 37.65 ? 603 LEU A CD1 1 ATOM 4891 C CD2 . LEU A 1 603 ? 34.238 101.832 -20.363 1.00 36.98 ? 603 LEU A CD2 1 ATOM 4892 N N . THR A 1 604 ? 30.217 99.690 -22.933 1.00 29.68 ? 604 THR A N 1 ATOM 4893 C CA . THR A 1 604 ? 29.263 99.242 -23.955 1.00 28.08 ? 604 THR A CA 1 ATOM 4894 C C . THR A 1 604 ? 28.330 98.118 -23.469 1.00 26.10 ? 604 THR A C 1 ATOM 4895 O O . THR A 1 604 ? 27.385 97.763 -24.167 1.00 25.17 ? 604 THR A O 1 ATOM 4896 C CB . THR A 1 604 ? 30.002 98.729 -25.211 1.00 28.39 ? 604 THR A CB 1 ATOM 4897 O OG1 . THR A 1 604 ? 30.874 97.640 -24.848 1.00 29.06 ? 604 THR A OG1 1 ATOM 4898 C CG2 . THR A 1 604 ? 30.951 99.791 -25.789 1.00 29.31 ? 604 THR A CG2 1 ATOM 4899 N N . LYS A 1 605 ? 28.623 97.554 -22.300 1.00 25.16 ? 605 LYS A N 1 ATOM 4900 C CA . LYS A 1 605 ? 27.858 96.431 -21.740 1.00 24.39 ? 605 LYS A CA 1 ATOM 4901 C C . LYS A 1 605 ? 27.889 95.223 -22.668 1.00 23.84 ? 605 LYS A C 1 ATOM 4902 O O . LYS A 1 605 ? 26.869 94.571 -22.895 1.00 24.24 ? 605 LYS A O 1 ATOM 4903 C CB . LYS A 1 605 ? 26.402 96.824 -21.432 1.00 24.82 ? 605 LYS A CB 1 ATOM 4904 C CG . LYS A 1 605 ? 26.272 97.965 -20.463 1.00 25.56 ? 605 LYS A CG 1 ATOM 4905 C CD . LYS A 1 605 ? 26.707 97.550 -19.069 1.00 27.01 ? 605 LYS A CD 1 ATOM 4906 C CE . LYS A 1 605 ? 26.617 98.747 -18.113 1.00 28.47 ? 605 LYS A CE 1 ATOM 4907 N NZ . LYS A 1 605 ? 26.895 98.346 -16.716 1.00 32.71 ? 605 LYS A NZ 1 ATOM 4908 N N . THR A 1 606 ? 29.061 94.946 -23.229 1.00 22.02 ? 606 THR A N 1 ATOM 4909 C CA . THR A 1 606 ? 29.231 93.746 -24.055 1.00 21.52 ? 606 THR A CA 1 ATOM 4910 C C . THR A 1 606 ? 30.463 93.030 -23.572 1.00 20.22 ? 606 THR A C 1 ATOM 4911 O O . THR A 1 606 ? 31.319 93.609 -22.883 1.00 20.49 ? 606 THR A O 1 ATOM 4912 C CB . THR A 1 606 ? 29.448 94.093 -25.533 1.00 21.92 ? 606 THR A CB 1 ATOM 4913 O OG1 . THR A 1 606 ? 30.607 94.933 -25.652 1.00 24.56 ? 606 THR A OG1 1 ATOM 4914 C CG2 . THR A 1 606 ? 28.275 94.898 -26.131 1.00 22.50 ? 606 THR A CG2 1 ATOM 4915 N N . ILE A 1 607 ? 30.559 91.758 -23.963 1.00 18.64 ? 607 ILE A N 1 ATOM 4916 C CA . ILE A 1 607 ? 31.745 90.946 -23.707 1.00 17.27 ? 607 ILE A CA 1 ATOM 4917 C C . ILE A 1 607 ? 32.430 90.709 -25.058 1.00 16.32 ? 607 ILE A C 1 ATOM 4918 O O . ILE A 1 607 ? 31.843 90.127 -25.972 1.00 15.60 ? 607 ILE A O 1 ATOM 4919 C CB . ILE A 1 607 ? 31.329 89.618 -23.089 1.00 17.28 ? 607 ILE A CB 1 ATOM 4920 C CG1 . ILE A 1 607 ? 30.512 89.850 -21.817 1.00 18.49 ? 607 ILE A CG1 1 ATOM 4921 C CG2 . ILE A 1 607 ? 32.576 88.767 -22.780 1.00 17.35 ? 607 ILE A CG2 1 ATOM 4922 C CD1 . ILE A 1 607 ? 29.743 88.622 -21.370 1.00 21.94 ? 607 ILE A CD1 1 ATOM 4923 N N . HIS A 1 608 ? 33.669 91.170 -25.213 1.00 16.42 ? 608 HIS A N 1 ATOM 4924 C CA . HIS A 1 608 ? 34.268 91.136 -26.542 1.00 16.74 ? 608 HIS A CA 1 ATOM 4925 C C . HIS A 1 608 ? 35.765 90.979 -26.416 1.00 15.26 ? 608 HIS A C 1 ATOM 4926 O O . HIS A 1 608 ? 36.328 91.288 -25.363 1.00 16.90 ? 608 HIS A O 1 ATOM 4927 C CB . HIS A 1 608 ? 33.913 92.387 -27.363 1.00 18.17 ? 608 HIS A CB 1 ATOM 4928 C CG . HIS A 1 608 ? 34.452 93.659 -26.792 1.00 21.21 ? 608 HIS A CG 1 ATOM 4929 N ND1 . HIS A 1 608 ? 35.409 94.417 -27.434 1.00 27.51 ? 608 HIS A ND1 1 ATOM 4930 C CD2 . HIS A 1 608 ? 34.168 94.306 -25.636 1.00 25.65 ? 608 HIS A CD2 1 ATOM 4931 C CE1 . HIS A 1 608 ? 35.688 95.482 -26.696 1.00 27.85 ? 608 HIS A CE1 1 ATOM 4932 N NE2 . HIS A 1 608 ? 34.943 95.441 -25.604 1.00 27.85 ? 608 HIS A NE2 1 ATOM 4933 N N . PRO A 1 609 ? 36.405 90.484 -27.466 1.00 14.98 ? 609 PRO A N 1 ATOM 4934 C CA . PRO A 1 609 ? 37.836 90.211 -27.411 1.00 15.28 ? 609 PRO A CA 1 ATOM 4935 C C . PRO A 1 609 ? 38.702 91.371 -27.853 1.00 16.19 ? 609 PRO A C 1 ATOM 4936 O O . PRO A 1 609 ? 38.335 92.158 -28.735 1.00 18.13 ? 609 PRO A O 1 ATOM 4937 C CB . PRO A 1 609 ? 37.986 89.051 -28.402 1.00 15.23 ? 609 PRO A CB 1 ATOM 4938 C CG . PRO A 1 609 ? 36.968 89.304 -29.456 1.00 15.15 ? 609 PRO A CG 1 ATOM 4939 C CD . PRO A 1 609 ? 35.829 90.046 -28.752 1.00 14.00 ? 609 PRO A CD 1 ATOM 4940 N N . GLN A 1 610 ? 39.880 91.416 -27.244 1.00 15.76 ? 610 GLN A N 1 ATOM 4941 C CA . GLN A 1 610 ? 40.918 92.362 -27.602 1.00 17.79 ? 610 GLN A CA 1 ATOM 4942 C C . GLN A 1 610 ? 42.169 91.568 -27.938 1.00 16.32 ? 610 GLN A C 1 ATOM 4943 O O . GLN A 1 610 ? 42.480 90.577 -27.265 1.00 15.98 ? 610 GLN A O 1 ATOM 4944 C CB . GLN A 1 610 ? 41.162 93.339 -26.452 1.00 18.97 ? 610 GLN A CB 1 ATOM 4945 C CG . GLN A 1 610 ? 39.923 94.249 -26.216 1.00 24.23 ? 610 GLN A CG 1 ATOM 4946 C CD . GLN A 1 610 ? 39.630 95.238 -27.374 1.00 29.09 ? 610 GLN A CD 1 ATOM 4947 O OE1 . GLN A 1 610 ? 38.646 95.081 -28.128 1.00 30.84 ? 610 GLN A OE1 1 ATOM 4948 N NE2 . GLN A 1 610 ? 40.468 96.261 -27.499 1.00 31.77 ? 610 GLN A NE2 1 ATOM 4949 N N . GLY A 1 611 ? 42.852 91.978 -28.987 1.00 16.16 ? 611 GLY A N 1 ATOM 4950 C CA . GLY A 1 611 ? 44.063 91.293 -29.418 1.00 16.11 ? 611 GLY A CA 1 ATOM 4951 C C . GLY A 1 611 ? 45.289 92.024 -28.915 1.00 16.61 ? 611 GLY A C 1 ATOM 4952 O O . GLY A 1 611 ? 45.311 93.267 -28.805 1.00 16.60 ? 611 GLY A O 1 ATOM 4953 N N . SER A 1 612 ? 46.321 91.262 -28.582 1.00 16.84 ? 612 SER A N 1 ATOM 4954 C CA . SER A 1 612 ? 47.581 91.881 -28.178 1.00 17.44 ? 612 SER A CA 1 ATOM 4955 C C . SER A 1 612 ? 48.275 92.494 -29.379 1.00 17.32 ? 612 SER A C 1 ATOM 4956 O O . SER A 1 612 ? 48.237 91.961 -30.488 1.00 17.80 ? 612 SER A O 1 ATOM 4957 C CB . SER A 1 612 ? 48.504 90.842 -27.538 1.00 16.59 ? 612 SER A CB 1 ATOM 4958 O OG . SER A 1 612 ? 49.727 91.465 -27.157 1.00 17.86 ? 612 SER A OG 1 ATOM 4959 N N . THR A 1 613 ? 48.951 93.621 -29.145 1.00 20.79 ? 613 THR A N 1 ATOM 4960 C CA . THR A 1 613 ? 49.763 94.189 -30.208 1.00 21.41 ? 613 THR A CA 1 ATOM 4961 C C . THR A 1 613 ? 51.256 93.935 -29.940 1.00 22.44 ? 613 THR A C 1 ATOM 4962 O O . THR A 1 613 ? 52.104 94.407 -30.711 1.00 23.71 ? 613 THR A O 1 ATOM 4963 C CB . THR A 1 613 ? 49.496 95.695 -30.374 1.00 22.51 ? 613 THR A CB 1 ATOM 4964 O OG1 . THR A 1 613 ? 49.794 96.350 -29.143 1.00 23.97 ? 613 THR A OG1 1 ATOM 4965 C CG2 . THR A 1 613 ? 47.992 95.973 -30.582 1.00 21.98 ? 613 THR A CG2 1 ATOM 4966 N N . THR A 1 614 ? 51.560 93.186 -28.876 1.00 22.19 ? 614 THR A N 1 ATOM 4967 C CA . THR A 1 614 ? 52.951 92.979 -28.454 1.00 22.92 ? 614 THR A CA 1 ATOM 4968 C C . THR A 1 614 ? 53.375 91.523 -28.342 1.00 21.94 ? 614 THR A C 1 ATOM 4969 O O . THR A 1 614 ? 54.573 91.222 -28.323 1.00 22.46 ? 614 THR A O 1 ATOM 4970 C CB . THR A 1 614 ? 53.234 93.677 -27.118 1.00 22.28 ? 614 THR A CB 1 ATOM 4971 O OG1 . THR A 1 614 ? 52.276 93.299 -26.121 1.00 26.40 ? 614 THR A OG1 1 ATOM 4972 C CG2 . THR A 1 614 ? 53.102 95.211 -27.237 1.00 25.36 ? 614 THR A CG2 1 ATOM 4973 N N . LYS A 1 615 ? 52.404 90.624 -28.236 1.00 19.38 ? 615 LYS A N 1 ATOM 4974 C CA . LYS A 1 615 ? 52.732 89.207 -28.153 1.00 18.17 ? 615 LYS A CA 1 ATOM 4975 C C . LYS A 1 615 ? 51.791 88.401 -29.032 1.00 16.76 ? 615 LYS A C 1 ATOM 4976 O O . LYS A 1 615 ? 50.672 88.833 -29.330 1.00 16.38 ? 615 LYS A O 1 ATOM 4977 C CB . LYS A 1 615 ? 52.799 88.685 -26.714 1.00 19.45 ? 615 LYS A CB 1 ATOM 4978 C CG . LYS A 1 615 ? 51.520 88.704 -25.928 1.00 20.36 ? 615 LYS A CG 1 ATOM 4979 C CD . LYS A 1 615 ? 51.750 88.198 -24.493 1.00 20.79 ? 615 LYS A CD 1 ATOM 4980 C CE . LYS A 1 615 ? 50.451 88.141 -23.721 1.00 22.18 ? 615 LYS A CE 1 ATOM 4981 N NZ . LYS A 1 615 ? 50.688 88.141 -22.230 1.00 25.46 ? 615 LYS A NZ 1 ATOM 4982 N N . TYR A 1 616 ? 52.271 87.232 -29.442 1.00 14.49 ? 616 TYR A N 1 ATOM 4983 C CA . TYR A 1 616 ? 51.617 86.380 -30.428 1.00 14.07 ? 616 TYR A CA 1 ATOM 4984 C C . TYR A 1 616 ? 51.768 84.956 -29.971 1.00 13.14 ? 616 TYR A C 1 ATOM 4985 O O . TYR A 1 616 ? 52.672 84.644 -29.184 1.00 13.48 ? 616 TYR A O 1 ATOM 4986 C CB . TYR A 1 616 ? 52.288 86.556 -31.803 1.00 14.80 ? 616 TYR A CB 1 ATOM 4987 C CG . TYR A 1 616 ? 52.294 88.017 -32.157 1.00 16.53 ? 616 TYR A CG 1 ATOM 4988 C CD1 . TYR A 1 616 ? 51.158 88.611 -32.722 1.00 16.19 ? 616 TYR A CD1 1 ATOM 4989 C CD2 . TYR A 1 616 ? 53.374 88.829 -31.803 1.00 16.89 ? 616 TYR A CD2 1 ATOM 4990 C CE1 . TYR A 1 616 ? 51.119 89.980 -32.969 1.00 19.94 ? 616 TYR A CE1 1 ATOM 4991 C CE2 . TYR A 1 616 ? 53.353 90.201 -32.064 1.00 19.09 ? 616 TYR A CE2 1 ATOM 4992 C CZ . TYR A 1 616 ? 52.216 90.751 -32.648 1.00 18.38 ? 616 TYR A CZ 1 ATOM 4993 O OH . TYR A 1 616 ? 52.175 92.109 -32.912 1.00 23.34 ? 616 TYR A OH 1 ATOM 4994 N N . ARG A 1 617 ? 50.907 84.078 -30.465 1.00 12.57 ? 617 ARG A N 1 ATOM 4995 C CA . ARG A 1 617 ? 50.986 82.655 -30.122 1.00 13.97 ? 617 ARG A CA 1 ATOM 4996 C C . ARG A 1 617 ? 51.614 81.917 -31.273 1.00 13.57 ? 617 ARG A C 1 ATOM 4997 O O . ARG A 1 617 ? 51.137 82.053 -32.414 1.00 14.62 ? 617 ARG A O 1 ATOM 4998 C CB . ARG A 1 617 ? 49.584 82.072 -29.936 1.00 14.95 ? 617 ARG A CB 1 ATOM 4999 C CG . ARG A 1 617 ? 48.881 82.402 -28.665 1.00 19.19 ? 617 ARG A CG 1 ATOM 5000 C CD . ARG A 1 617 ? 47.499 81.748 -28.585 1.00 18.94 ? 617 ARG A CD 1 ATOM 5001 N NE . ARG A 1 617 ? 47.545 80.288 -28.627 1.00 20.25 ? 617 ARG A NE 1 ATOM 5002 C CZ . ARG A 1 617 ? 46.855 79.513 -29.473 1.00 22.28 ? 617 ARG A CZ 1 ATOM 5003 N NH1 . ARG A 1 617 ? 46.039 80.037 -30.387 1.00 21.10 ? 617 ARG A NH1 1 ATOM 5004 N NH2 . ARG A 1 617 ? 46.984 78.198 -29.413 1.00 20.11 ? 617 ARG A NH2 1 ATOM 5005 N N . ILE A 1 618 ? 52.647 81.120 -31.019 1.00 12.34 ? 618 ILE A N 1 ATOM 5006 C CA . ILE A 1 618 ? 53.152 80.220 -32.040 1.00 12.52 ? 618 ILE A CA 1 ATOM 5007 C C . ILE A 1 618 ? 52.805 78.796 -31.662 1.00 11.32 ? 618 ILE A C 1 ATOM 5008 O O . ILE A 1 618 ? 52.965 78.404 -30.508 1.00 12.03 ? 618 ILE A O 1 ATOM 5009 C CB . ILE A 1 618 ? 54.646 80.406 -32.300 1.00 12.19 ? 618 ILE A CB 1 ATOM 5010 C CG1 . ILE A 1 618 ? 55.050 79.551 -33.499 1.00 14.65 ? 618 ILE A CG1 1 ATOM 5011 C CG2 . ILE A 1 618 ? 55.518 80.113 -31.041 1.00 13.76 ? 618 ILE A CG2 1 ATOM 5012 C CD1 . ILE A 1 618 ? 56.335 79.960 -34.159 1.00 13.94 ? 618 ILE A CD1 1 ATOM 5013 N N . ILE A 1 619 ? 52.344 78.025 -32.630 1.00 11.50 ? 619 ILE A N 1 ATOM 5014 C CA . ILE A 1 619 ? 51.855 76.660 -32.431 1.00 11.31 ? 619 ILE A CA 1 ATOM 5015 C C . ILE A 1 619 ? 52.566 75.721 -33.371 1.00 11.35 ? 619 ILE A C 1 ATOM 5016 O O . ILE A 1 619 ? 52.755 76.051 -34.565 1.00 11.05 ? 619 ILE A O 1 ATOM 5017 C CB . ILE A 1 619 ? 50.343 76.641 -32.798 1.00 13.92 ? 619 ILE A CB 1 ATOM 5018 C CG1 . ILE A 1 619 ? 49.597 77.683 -31.974 1.00 16.36 ? 619 ILE A CG1 1 ATOM 5019 C CG2 . ILE A 1 619 ? 49.722 75.283 -32.653 1.00 17.29 ? 619 ILE A CG2 1 ATOM 5020 C CD1 . ILE A 1 619 ? 48.519 78.401 -32.778 1.00 17.85 ? 619 ILE A CD1 1 ATOM 5021 N N . PHE A 1 620 ? 52.988 74.554 -32.908 1.00 9.95 ? 620 PHE A N 1 ATOM 5022 C CA . PHE A 1 620 ? 53.641 73.594 -33.784 1.00 9.82 ? 620 PHE A CA 1 ATOM 5023 C C . PHE A 1 620 ? 53.510 72.208 -33.158 1.00 10.15 ? 620 PHE A C 1 ATOM 5024 O O . PHE A 1 620 ? 53.219 72.070 -31.959 1.00 10.47 ? 620 PHE A O 1 ATOM 5025 C CB . PHE A 1 620 ? 55.117 73.964 -33.998 1.00 9.39 ? 620 PHE A CB 1 ATOM 5026 C CG . PHE A 1 620 ? 55.982 73.891 -32.740 1.00 9.42 ? 620 PHE A CG 1 ATOM 5027 C CD1 . PHE A 1 620 ? 56.165 75.009 -31.945 1.00 10.72 ? 620 PHE A CD1 1 ATOM 5028 C CD2 . PHE A 1 620 ? 56.679 72.715 -32.414 1.00 11.72 ? 620 PHE A CD2 1 ATOM 5029 C CE1 . PHE A 1 620 ? 56.976 74.941 -30.794 1.00 10.50 ? 620 PHE A CE1 1 ATOM 5030 C CE2 . PHE A 1 620 ? 57.500 72.655 -31.289 1.00 11.19 ? 620 PHE A CE2 1 ATOM 5031 C CZ . PHE A 1 620 ? 57.640 73.763 -30.491 1.00 11.62 ? 620 PHE A CZ 1 ATOM 5032 N N . LYS A 1 621 ? 53.714 71.189 -33.968 1.00 10.14 ? 621 LYS A N 1 ATOM 5033 C CA . LYS A 1 621 ? 53.639 69.829 -33.488 1.00 11.26 ? 621 LYS A CA 1 ATOM 5034 C C . LYS A 1 621 ? 54.948 69.380 -32.886 1.00 11.19 ? 621 LYS A C 1 ATOM 5035 O O . LYS A 1 621 ? 55.982 69.393 -33.545 1.00 12.68 ? 621 LYS A O 1 ATOM 5036 C CB . LYS A 1 621 ? 53.226 68.919 -34.640 1.00 12.22 ? 621 LYS A CB 1 ATOM 5037 C CG . LYS A 1 621 ? 52.831 67.526 -34.185 1.00 14.87 ? 621 LYS A CG 1 ATOM 5038 C CD . LYS A 1 621 ? 51.906 66.855 -35.189 1.00 21.98 ? 621 LYS A CD 1 ATOM 5039 C CE . LYS A 1 621 ? 52.574 66.695 -36.530 1.00 23.54 ? 621 LYS A CE 1 ATOM 5040 N NZ . LYS A 1 621 ? 51.686 66.006 -37.528 1.00 28.43 ? 621 LYS A NZ 1 ATOM 5041 N N . ALA A 1 622 ? 54.909 69.012 -31.611 1.00 11.17 ? 622 ALA A N 1 ATOM 5042 C CA . ALA A 1 622 ? 56.070 68.419 -30.970 1.00 11.06 ? 622 ALA A CA 1 ATOM 5043 C C . ALA A 1 622 ? 55.960 66.905 -30.998 1.00 11.41 ? 622 ALA A C 1 ATOM 5044 O O . ALA A 1 622 ? 54.891 66.374 -30.759 1.00 12.70 ? 622 ALA A O 1 ATOM 5045 C CB . ALA A 1 622 ? 56.186 68.898 -29.503 1.00 11.32 ? 622 ALA A CB 1 ATOM 5046 N N . ARG A 1 623 ? 57.064 66.228 -31.279 1.00 10.52 ? 623 ARG A N 1 ATOM 5047 C CA . ARG A 1 623 ? 57.091 64.766 -31.295 1.00 11.07 ? 623 ARG A CA 1 ATOM 5048 C C . ARG A 1 623 ? 58.069 64.340 -30.232 1.00 10.00 ? 623 ARG A C 1 ATOM 5049 O O . ARG A 1 623 ? 59.229 64.732 -30.249 1.00 11.00 ? 623 ARG A O 1 ATOM 5050 C CB . ARG A 1 623 ? 57.539 64.253 -32.669 1.00 12.20 ? 623 ARG A CB 1 ATOM 5051 C CG . ARG A 1 623 ? 57.622 62.741 -32.739 1.00 14.44 ? 623 ARG A CG 1 ATOM 5052 C CD . ARG A 1 623 ? 57.862 62.194 -34.188 1.00 15.90 ? 623 ARG A CD 1 ATOM 5053 N NE . ARG A 1 623 ? 57.874 60.729 -34.150 1.00 20.29 ? 623 ARG A NE 1 ATOM 5054 C CZ . ARG A 1 623 ? 58.981 60.020 -34.031 1.00 23.34 ? 623 ARG A CZ 1 ATOM 5055 N NH1 . ARG A 1 623 ? 60.158 60.630 -33.970 1.00 25.84 ? 623 ARG A NH1 1 ATOM 5056 N NH2 . ARG A 1 623 ? 58.916 58.701 -33.953 1.00 23.63 ? 623 ARG A NH2 1 ATOM 5057 N N . VAL A 1 624 ? 57.568 63.591 -29.259 1.00 9.32 ? 624 VAL A N 1 ATOM 5058 C CA . VAL A 1 624 ? 58.307 63.336 -28.017 1.00 8.93 ? 624 VAL A CA 1 ATOM 5059 C C . VAL A 1 624 ? 58.348 61.833 -27.699 1.00 8.53 ? 624 VAL A C 1 ATOM 5060 O O . VAL A 1 624 ? 57.335 61.155 -27.810 1.00 9.09 ? 624 VAL A O 1 ATOM 5061 C CB . VAL A 1 624 ? 57.664 64.115 -26.839 1.00 9.01 ? 624 VAL A CB 1 ATOM 5062 C CG1 . VAL A 1 624 ? 58.614 64.111 -25.636 1.00 10.65 ? 624 VAL A CG1 1 ATOM 5063 C CG2 . VAL A 1 624 ? 57.358 65.566 -27.255 1.00 10.33 ? 624 VAL A CG2 1 ATOM 5064 N N . PRO A 1 625 ? 59.543 61.328 -27.343 1.00 9.27 ? 625 PRO A N 1 ATOM 5065 C CA . PRO A 1 625 ? 59.672 59.889 -27.060 1.00 9.11 ? 625 PRO A CA 1 ATOM 5066 C C . PRO A 1 625 ? 58.806 59.439 -25.867 1.00 9.24 ? 625 PRO A C 1 ATOM 5067 O O . PRO A 1 625 ? 58.395 60.264 -25.018 1.00 8.99 ? 625 PRO A O 1 ATOM 5068 C CB . PRO A 1 625 ? 61.166 59.722 -26.720 1.00 10.45 ? 625 PRO A CB 1 ATOM 5069 C CG . PRO A 1 625 ? 61.858 60.884 -27.377 1.00 11.07 ? 625 PRO A CG 1 ATOM 5070 C CD . PRO A 1 625 ? 60.844 62.023 -27.234 1.00 9.72 ? 625 PRO A CD 1 ATOM 5071 N N . PRO A 1 626 ? 58.595 58.140 -25.740 1.00 9.09 ? 626 PRO A N 1 ATOM 5072 C CA . PRO A 1 626 ? 57.917 57.595 -24.542 1.00 8.51 ? 626 PRO A CA 1 ATOM 5073 C C . PRO A 1 626 ? 58.693 58.024 -23.302 1.00 8.61 ? 626 PRO A C 1 ATOM 5074 O O . PRO A 1 626 ? 59.920 57.857 -23.231 1.00 8.72 ? 626 PRO A O 1 ATOM 5075 C CB . PRO A 1 626 ? 58.060 56.073 -24.723 1.00 8.79 ? 626 PRO A CB 1 ATOM 5076 C CG . PRO A 1 626 ? 58.317 55.890 -26.242 1.00 10.20 ? 626 PRO A CG 1 ATOM 5077 C CD . PRO A 1 626 ? 59.107 57.076 -26.637 1.00 10.53 ? 626 PRO A CD 1 ATOM 5078 N N . MET A 1 627 ? 57.982 58.582 -22.317 1.00 7.45 ? 627 MET A N 1 ATOM 5079 C CA . MET A 1 627 ? 58.626 58.959 -21.029 1.00 7.76 ? 627 MET A CA 1 ATOM 5080 C C . MET A 1 627 ? 59.893 59.773 -21.279 1.00 8.03 ? 627 MET A C 1 ATOM 5081 O O . MET A 1 627 ? 60.915 59.608 -20.616 1.00 9.06 ? 627 MET A O 1 ATOM 5082 C CB . MET A 1 627 ? 58.905 57.727 -20.173 1.00 8.74 ? 627 MET A CB 1 ATOM 5083 C CG . MET A 1 627 ? 57.612 57.018 -19.823 1.00 8.43 ? 627 MET A CG 1 ATOM 5084 S SD . MET A 1 627 ? 57.805 55.346 -19.136 1.00 11.27 ? 627 MET A SD 1 ATOM 5085 C CE . MET A 1 627 ? 58.710 55.663 -17.690 1.00 12.34 ? 627 MET A CE 1 ATOM 5086 N N . GLY A 1 628 ? 59.819 60.660 -22.273 1.00 7.91 ? 628 GLY A N 1 ATOM 5087 C CA . GLY A 1 628 ? 61.028 61.300 -22.781 1.00 8.96 ? 628 GLY A CA 1 ATOM 5088 C C . GLY A 1 628 ? 60.915 62.789 -23.004 1.00 8.47 ? 628 GLY A C 1 ATOM 5089 O O . GLY A 1 628 ? 59.922 63.425 -22.594 1.00 8.30 ? 628 GLY A O 1 ATOM 5090 N N . LEU A 1 629 ? 61.950 63.346 -23.636 1.00 8.21 ? 629 LEU A N 1 ATOM 5091 C CA . LEU A 1 629 ? 62.093 64.803 -23.836 1.00 8.65 ? 629 LEU A CA 1 ATOM 5092 C C . LEU A 1 629 ? 62.509 65.078 -25.273 1.00 8.92 ? 629 LEU A C 1 ATOM 5093 O O . LEU A 1 629 ? 63.282 64.295 -25.882 1.00 9.54 ? 629 LEU A O 1 ATOM 5094 C CB . LEU A 1 629 ? 63.180 65.408 -22.935 1.00 8.53 ? 629 LEU A CB 1 ATOM 5095 C CG . LEU A 1 629 ? 62.956 65.264 -21.435 1.00 8.84 ? 629 LEU A CG 1 ATOM 5096 C CD1 . LEU A 1 629 ? 64.227 65.468 -20.653 1.00 9.64 ? 629 LEU A CD1 1 ATOM 5097 C CD2 . LEU A 1 629 ? 61.878 66.254 -20.990 1.00 9.25 ? 629 LEU A CD2 1 ATOM 5098 N N . ALA A 1 630 ? 62.060 66.217 -25.788 1.00 8.63 ? 630 ALA A N 1 ATOM 5099 C CA . ALA A 1 630 ? 62.436 66.667 -27.140 1.00 9.39 ? 630 ALA A CA 1 ATOM 5100 C C . ALA A 1 630 ? 62.660 68.157 -27.117 1.00 9.53 ? 630 ALA A C 1 ATOM 5101 O O . ALA A 1 630 ? 61.841 68.910 -26.583 1.00 9.81 ? 630 ALA A O 1 ATOM 5102 C CB . ALA A 1 630 ? 61.393 66.307 -28.160 1.00 10.33 ? 630 ALA A CB 1 ATOM 5103 N N . THR A 1 631 ? 63.762 68.596 -27.717 1.00 9.45 ? 631 THR A N 1 ATOM 5104 C CA . THR A 1 631 ? 64.152 70.025 -27.752 1.00 10.74 ? 631 THR A CA 1 ATOM 5105 C C . THR A 1 631 ? 63.849 70.670 -29.106 1.00 10.90 ? 631 THR A C 1 ATOM 5106 O O . THR A 1 631 ? 64.097 70.055 -30.161 1.00 11.07 ? 631 THR A O 1 ATOM 5107 C CB . THR A 1 631 ? 65.661 70.104 -27.482 1.00 11.47 ? 631 THR A CB 1 ATOM 5108 O OG1 . THR A 1 631 ? 65.931 69.420 -26.246 1.00 10.55 ? 631 THR A OG1 1 ATOM 5109 C CG2 . THR A 1 631 ? 66.163 71.566 -27.271 1.00 13.21 ? 631 THR A CG2 1 ATOM 5110 N N . TYR A 1 632 ? 63.325 71.888 -29.080 1.00 10.16 ? 632 TYR A N 1 ATOM 5111 C CA . TYR A 1 632 ? 63.099 72.673 -30.292 1.00 10.17 ? 632 TYR A CA 1 ATOM 5112 C C . TYR A 1 632 ? 63.666 74.058 -30.090 1.00 10.39 ? 632 TYR A C 1 ATOM 5113 O O . TYR A 1 632 ? 63.990 74.478 -28.981 1.00 10.57 ? 632 TYR A O 1 ATOM 5114 C CB . TYR A 1 632 ? 61.602 72.761 -30.619 1.00 11.21 ? 632 TYR A CB 1 ATOM 5115 C CG . TYR A 1 632 ? 61.014 71.435 -31.019 1.00 10.92 ? 632 TYR A CG 1 ATOM 5116 C CD1 . TYR A 1 632 ? 60.601 70.500 -30.048 1.00 11.47 ? 632 TYR A CD1 1 ATOM 5117 C CD2 . TYR A 1 632 ? 60.813 71.110 -32.367 1.00 11.37 ? 632 TYR A CD2 1 ATOM 5118 C CE1 . TYR A 1 632 ? 60.071 69.268 -30.434 1.00 12.14 ? 632 TYR A CE1 1 ATOM 5119 C CE2 . TYR A 1 632 ? 60.285 69.890 -32.750 1.00 12.37 ? 632 TYR A CE2 1 ATOM 5120 C CZ . TYR A 1 632 ? 59.915 68.977 -31.783 1.00 12.01 ? 632 TYR A CZ 1 ATOM 5121 O OH . TYR A 1 632 ? 59.405 67.756 -32.169 1.00 13.60 ? 632 TYR A OH 1 ATOM 5122 N N . VAL A 1 633 ? 63.829 74.772 -31.208 1.00 10.52 ? 633 VAL A N 1 ATOM 5123 C CA . VAL A 1 633 ? 64.377 76.117 -31.199 1.00 11.38 ? 633 VAL A CA 1 ATOM 5124 C C . VAL A 1 633 ? 63.432 77.054 -31.934 1.00 10.38 ? 633 VAL A C 1 ATOM 5125 O O . VAL A 1 633 ? 62.960 76.732 -33.011 1.00 10.78 ? 633 VAL A O 1 ATOM 5126 C CB . VAL A 1 633 ? 65.776 76.158 -31.876 1.00 11.34 ? 633 VAL A CB 1 ATOM 5127 C CG1 . VAL A 1 633 ? 66.359 77.567 -31.834 1.00 13.39 ? 633 VAL A CG1 1 ATOM 5128 C CG2 . VAL A 1 633 ? 66.719 75.188 -31.169 1.00 13.63 ? 633 VAL A CG2 1 ATOM 5129 N N . LEU A 1 634 ? 63.136 78.185 -31.310 1.00 10.15 ? 634 LEU A N 1 ATOM 5130 C CA . LEU A 1 634 ? 62.328 79.250 -31.908 1.00 10.82 ? 634 LEU A CA 1 ATOM 5131 C C . LEU A 1 634 ? 63.266 80.387 -32.288 1.00 11.66 ? 634 LEU A C 1 ATOM 5132 O O . LEU A 1 634 ? 64.034 80.847 -31.448 1.00 11.65 ? 634 LEU A O 1 ATOM 5133 C CB . LEU A 1 634 ? 61.303 79.779 -30.903 1.00 11.38 ? 634 LEU A CB 1 ATOM 5134 C CG . LEU A 1 634 ? 60.354 78.790 -30.226 1.00 17.36 ? 634 LEU A CG 1 ATOM 5135 C CD1 . LEU A 1 634 ? 59.219 79.554 -29.576 1.00 16.97 ? 634 LEU A CD1 1 ATOM 5136 C CD2 . LEU A 1 634 ? 59.817 77.760 -31.138 1.00 20.45 ? 634 LEU A CD2 1 ATOM 5137 N N . THR A 1 635 ? 63.189 80.814 -33.566 1.00 12.00 ? 635 THR A N 1 ATOM 5138 C CA . THR A 1 635 ? 64.126 81.821 -34.090 1.00 12.55 ? 635 THR A CA 1 ATOM 5139 C C . THR A 1 635 ? 63.354 82.960 -34.742 1.00 13.64 ? 635 THR A C 1 ATOM 5140 O O . THR A 1 635 ? 62.437 82.728 -35.530 1.00 13.88 ? 635 THR A O 1 ATOM 5141 C CB . THR A 1 635 ? 65.072 81.164 -35.130 1.00 13.76 ? 635 THR A CB 1 ATOM 5142 O OG1 . THR A 1 635 ? 65.782 80.080 -34.498 1.00 13.89 ? 635 THR A OG1 1 ATOM 5143 C CG2 . THR A 1 635 ? 66.190 82.161 -35.564 1.00 14.33 ? 635 THR A CG2 1 ATOM 5144 N N . ILE A 1 636 ? 63.750 84.191 -34.428 1.00 14.66 ? 636 ILE A N 1 ATOM 5145 C CA . ILE A 1 636 ? 63.092 85.352 -35.038 1.00 16.17 ? 636 ILE A CA 1 ATOM 5146 C C . ILE A 1 636 ? 63.707 85.629 -36.415 1.00 18.15 ? 636 ILE A C 1 ATOM 5147 O O . ILE A 1 636 ? 64.888 85.340 -36.656 1.00 17.63 ? 636 ILE A O 1 ATOM 5148 C CB . ILE A 1 636 ? 63.191 86.594 -34.112 1.00 15.95 ? 636 ILE A CB 1 ATOM 5149 C CG1 . ILE A 1 636 ? 62.195 87.684 -34.538 1.00 16.16 ? 636 ILE A CG1 1 ATOM 5150 C CG2 . ILE A 1 636 ? 64.647 87.123 -34.021 1.00 16.84 ? 636 ILE A CG2 1 ATOM 5151 C CD1 . ILE A 1 636 ? 62.140 88.879 -33.567 1.00 18.24 ? 636 ILE A CD1 1 ATOM 5152 N N . SER A 1 637 ? 62.884 86.167 -37.314 1.00 19.54 ? 637 SER A N 1 ATOM 5153 C CA . SER A 1 637 ? 63.392 86.723 -38.574 1.00 22.09 ? 637 SER A CA 1 ATOM 5154 C C . SER A 1 637 ? 62.765 88.093 -38.835 1.00 23.37 ? 637 SER A C 1 ATOM 5155 O O . SER A 1 637 ? 61.876 88.520 -38.103 1.00 22.37 ? 637 SER A O 1 ATOM 5156 C CB . SER A 1 637 ? 63.148 85.751 -39.729 1.00 23.72 ? 637 SER A CB 1 ATOM 5157 O OG . SER A 1 637 ? 61.762 85.530 -39.907 1.00 26.61 ? 637 SER A OG 1 ATOM 5158 N N . ASP A 1 638 ? 63.252 88.801 -39.863 1.00 25.58 ? 638 ASP A N 1 ATOM 5159 C CA . ASP A 1 638 ? 62.726 90.143 -40.145 1.00 27.73 ? 638 ASP A CA 1 ATOM 5160 C C . ASP A 1 638 ? 61.374 90.123 -40.864 1.00 27.64 ? 638 ASP A C 1 ATOM 5161 O O . ASP A 1 638 ? 60.626 91.114 -40.831 1.00 29.11 ? 638 ASP A O 1 ATOM 5162 C CB . ASP A 1 638 ? 63.750 91.035 -40.877 1.00 28.45 ? 638 ASP A CB 1 ATOM 5163 C CG . ASP A 1 638 ? 64.160 90.492 -42.241 1.00 31.87 ? 638 ASP A CG 1 ATOM 5164 O OD1 . ASP A 1 638 ? 63.986 89.282 -42.524 1.00 35.36 ? 638 ASP A OD1 1 ATOM 5165 O OD2 . ASP A 1 638 ? 64.688 91.230 -43.107 1.00 37.05 ? 638 ASP A OD2 1 ATOM 5166 N N . SER A 1 639 ? 61.052 88.992 -41.485 1.00 27.19 ? 639 SER A N 1 ATOM 5167 C CA . SER A 1 639 ? 59.809 88.851 -42.231 1.00 27.12 ? 639 SER A CA 1 ATOM 5168 C C . SER A 1 639 ? 59.241 87.439 -42.126 1.00 26.74 ? 639 SER A C 1 ATOM 5169 O O . SER A 1 639 ? 59.859 86.562 -41.507 1.00 25.30 ? 639 SER A O 1 ATOM 5170 C CB . SER A 1 639 ? 60.039 89.226 -43.703 1.00 27.35 ? 639 SER A CB 1 ATOM 5171 O OG . SER A 1 639 ? 61.029 88.391 -44.284 1.00 29.08 ? 639 SER A OG 1 ATOM 5172 N N . LYS A 1 640 ? 58.076 87.227 -42.741 1.00 25.63 ? 640 LYS A N 1 ATOM 5173 C CA . LYS A 1 640 ? 57.393 85.933 -42.717 1.00 25.14 ? 640 LYS A CA 1 ATOM 5174 C C . LYS A 1 640 ? 58.356 84.798 -43.053 1.00 24.24 ? 640 LYS A C 1 ATOM 5175 O O . LYS A 1 640 ? 58.931 84.767 -44.142 1.00 24.45 ? 640 LYS A O 1 ATOM 5176 C CB . LYS A 1 640 ? 56.220 85.901 -43.702 1.00 25.32 ? 640 LYS A CB 1 ATOM 5177 C CG . LYS A 1 640 ? 54.991 86.747 -43.375 1.00 27.87 ? 640 LYS A CG 1 ATOM 5178 C CD . LYS A 1 640 ? 53.817 86.236 -44.233 1.00 29.87 ? 640 LYS A CD 1 ATOM 5179 C CE . LYS A 1 640 ? 52.700 87.246 -44.372 1.00 31.22 ? 640 LYS A CE 1 ATOM 5180 N NZ . LYS A 1 640 ? 51.374 86.575 -44.567 1.00 34.12 ? 640 LYS A NZ 1 ATOM 5181 N N . PRO A 1 641 ? 58.549 83.876 -42.109 1.00 22.86 ? 641 PRO A N 1 ATOM 5182 C CA . PRO A 1 641 ? 59.352 82.672 -42.335 1.00 22.17 ? 641 PRO A CA 1 ATOM 5183 C C . PRO A 1 641 ? 58.691 81.709 -43.315 1.00 21.16 ? 641 PRO A C 1 ATOM 5184 O O . PRO A 1 641 ? 57.468 81.624 -43.360 1.00 20.51 ? 641 PRO A O 1 ATOM 5185 C CB . PRO A 1 641 ? 59.365 82.010 -40.948 1.00 22.44 ? 641 PRO A CB 1 ATOM 5186 C CG . PRO A 1 641 ? 59.032 83.087 -40.026 1.00 22.70 ? 641 PRO A CG 1 ATOM 5187 C CD . PRO A 1 641 ? 58.046 83.940 -40.724 1.00 22.77 ? 641 PRO A CD 1 ATOM 5188 N N . GLU A 1 642 ? 59.492 80.943 -44.040 1.00 21.57 ? 642 GLU A N 1 ATOM 5189 C CA . GLU A 1 642 ? 58.971 79.980 -44.998 1.00 21.97 ? 642 GLU A CA 1 ATOM 5190 C C . GLU A 1 642 ? 58.014 78.927 -44.416 1.00 21.49 ? 642 GLU A C 1 ATOM 5191 O O . GLU A 1 642 ? 57.042 78.536 -45.057 1.00 21.79 ? 642 GLU A O 1 ATOM 5192 C CB . GLU A 1 642 ? 60.140 79.278 -45.694 1.00 22.67 ? 642 GLU A CB 1 ATOM 5193 C CG . GLU A 1 642 ? 59.726 78.245 -46.716 1.00 26.24 ? 642 GLU A CG 1 ATOM 5194 C CD . GLU A 1 642 ? 60.907 77.684 -47.488 1.00 30.78 ? 642 GLU A CD 1 ATOM 5195 O OE1 . GLU A 1 642 ? 61.990 78.318 -47.474 1.00 34.81 ? 642 GLU A OE1 1 ATOM 5196 O OE2 . GLU A 1 642 ? 60.748 76.603 -48.107 1.00 35.09 ? 642 GLU A OE2 1 ATOM 5197 N N . HIS A 1 643 ? 58.280 78.465 -43.201 1.00 20.14 ? 643 HIS A N 1 ATOM 5198 C CA . HIS A 1 643 ? 57.518 77.339 -42.661 1.00 18.70 ? 643 HIS A CA 1 ATOM 5199 C C . HIS A 1 643 ? 56.535 77.728 -41.557 1.00 17.64 ? 643 HIS A C 1 ATOM 5200 O O . HIS A 1 643 ? 56.094 76.881 -40.796 1.00 16.55 ? 643 HIS A O 1 ATOM 5201 C CB . HIS A 1 643 ? 58.448 76.246 -42.158 1.00 19.37 ? 643 HIS A CB 1 ATOM 5202 C CG . HIS A 1 643 ? 59.350 75.696 -43.214 1.00 19.99 ? 643 HIS A CG 1 ATOM 5203 N ND1 . HIS A 1 643 ? 58.970 74.689 -44.065 1.00 23.07 ? 643 HIS A ND1 1 ATOM 5204 C CD2 . HIS A 1 643 ? 60.608 76.032 -43.566 1.00 23.37 ? 643 HIS A CD2 1 ATOM 5205 C CE1 . HIS A 1 643 ? 59.963 74.417 -44.891 1.00 22.16 ? 643 HIS A CE1 1 ATOM 5206 N NE2 . HIS A 1 643 ? 60.969 75.217 -44.606 1.00 23.04 ? 643 HIS A NE2 1 ATOM 5207 N N . THR A 1 644 ? 56.200 79.006 -41.496 1.00 15.57 ? 644 THR A N 1 ATOM 5208 C CA . THR A 1 644 ? 55.226 79.511 -40.537 1.00 15.07 ? 644 THR A CA 1 ATOM 5209 C C . THR A 1 644 ? 54.074 80.135 -41.307 1.00 15.68 ? 644 THR A C 1 ATOM 5210 O O . THR A 1 644 ? 54.323 80.948 -42.217 1.00 16.39 ? 644 THR A O 1 ATOM 5211 C CB . THR A 1 644 ? 55.890 80.531 -39.609 1.00 14.84 ? 644 THR A CB 1 ATOM 5212 O OG1 . THR A 1 644 ? 56.929 79.860 -38.864 1.00 15.47 ? 644 THR A OG1 1 ATOM 5213 C CG2 . THR A 1 644 ? 54.893 81.093 -38.537 1.00 15.14 ? 644 THR A CG2 1 ATOM 5214 N N . SER A 1 645 ? 52.845 79.743 -40.980 1.00 14.05 ? 645 SER A N 1 ATOM 5215 C CA . SER A 1 645 ? 51.641 80.354 -41.543 1.00 14.06 ? 645 SER A CA 1 ATOM 5216 C C . SER A 1 645 ? 50.921 81.173 -40.498 1.00 13.42 ? 645 SER A C 1 ATOM 5217 O O . SER A 1 645 ? 51.255 81.086 -39.325 1.00 13.28 ? 645 SER A O 1 ATOM 5218 C CB . SER A 1 645 ? 50.699 79.284 -42.058 1.00 14.09 ? 645 SER A CB 1 ATOM 5219 O OG . SER A 1 645 ? 50.221 78.493 -40.958 1.00 15.86 ? 645 SER A OG 1 ATOM 5220 N N . TYR A 1 646 ? 49.953 81.993 -40.914 1.00 13.00 ? 646 TYR A N 1 ATOM 5221 C CA . TYR A 1 646 ? 49.272 82.936 -40.027 1.00 13.33 ? 646 TYR A CA 1 ATOM 5222 C C . TYR A 1 646 ? 47.798 82.691 -40.131 1.00 13.56 ? 646 TYR A C 1 ATOM 5223 O O . TYR A 1 646 ? 47.258 82.582 -41.237 1.00 15.41 ? 646 TYR A O 1 ATOM 5224 C CB . TYR A 1 646 ? 49.601 84.387 -40.437 1.00 15.43 ? 646 TYR A CB 1 ATOM 5225 C CG . TYR A 1 646 ? 51.076 84.612 -40.237 1.00 14.26 ? 646 TYR A CG 1 ATOM 5226 C CD1 . TYR A 1 646 ? 51.559 84.995 -38.987 1.00 13.31 ? 646 TYR A CD1 1 ATOM 5227 C CD2 . TYR A 1 646 ? 52.005 84.304 -41.246 1.00 14.75 ? 646 TYR A CD2 1 ATOM 5228 C CE1 . TYR A 1 646 ? 52.913 85.120 -38.756 1.00 14.17 ? 646 TYR A CE1 1 ATOM 5229 C CE2 . TYR A 1 646 ? 53.367 84.430 -41.014 1.00 16.72 ? 646 TYR A CE2 1 ATOM 5230 C CZ . TYR A 1 646 ? 53.803 84.853 -39.770 1.00 15.77 ? 646 TYR A CZ 1 ATOM 5231 O OH . TYR A 1 646 ? 55.145 84.977 -39.479 1.00 17.33 ? 646 TYR A OH 1 ATOM 5232 N N . ALA A 1 647 ? 47.137 82.585 -38.978 1.00 12.30 ? 647 ALA A N 1 ATOM 5233 C CA . ALA A 1 647 ? 45.709 82.368 -38.945 1.00 12.15 ? 647 ALA A CA 1 ATOM 5234 C C . ALA A 1 647 ? 44.960 83.593 -39.458 1.00 12.38 ? 647 ALA A C 1 ATOM 5235 O O . ALA A 1 647 ? 45.365 84.738 -39.261 1.00 12.51 ? 647 ALA A O 1 ATOM 5236 C CB . ALA A 1 647 ? 45.265 82.078 -37.503 1.00 13.17 ? 647 ALA A CB 1 ATOM 5237 N N . SER A 1 648 ? 43.816 83.349 -40.057 1.00 11.81 ? 648 SER A N 1 ATOM 5238 C CA . SER A 1 648 ? 42.876 84.446 -40.280 1.00 12.84 ? 648 SER A CA 1 ATOM 5239 C C . SER A 1 648 ? 41.979 84.607 -39.046 1.00 12.23 ? 648 SER A C 1 ATOM 5240 O O . SER A 1 648 ? 41.788 83.651 -38.257 1.00 12.00 ? 648 SER A O 1 ATOM 5241 C CB . SER A 1 648 ? 42.039 84.185 -41.520 1.00 14.26 ? 648 SER A CB 1 ATOM 5242 O OG . SER A 1 648 ? 41.322 82.999 -41.401 1.00 18.63 ? 648 SER A OG 1 ATOM 5243 N N . ASN A 1 649 ? 41.383 85.778 -38.880 1.00 11.29 ? 649 ASN A N 1 ATOM 5244 C CA . ASN A 1 649 ? 40.515 86.058 -37.751 1.00 11.48 ? 649 ASN A CA 1 ATOM 5245 C C . ASN A 1 649 ? 39.281 86.798 -38.223 1.00 11.16 ? 649 ASN A C 1 ATOM 5246 O O . ASN A 1 649 ? 39.418 87.776 -39.004 1.00 12.33 ? 649 ASN A O 1 ATOM 5247 C CB . ASN A 1 649 ? 41.242 86.868 -36.678 1.00 11.03 ? 649 ASN A CB 1 ATOM 5248 C CG . ASN A 1 649 ? 42.440 86.133 -36.108 1.00 12.56 ? 649 ASN A CG 1 ATOM 5249 O OD1 . ASN A 1 649 ? 42.303 85.373 -35.125 1.00 12.64 ? 649 ASN A OD1 1 ATOM 5250 N ND2 . ASN A 1 649 ? 43.592 86.292 -36.730 1.00 12.45 ? 649 ASN A ND2 1 ATOM 5251 N N . LEU A 1 650 ? 38.117 86.378 -37.763 1.00 10.98 ? 650 LEU A N 1 ATOM 5252 C CA . LEU A 1 650 ? 36.841 86.961 -38.170 1.00 11.49 ? 650 LEU A CA 1 ATOM 5253 C C . LEU A 1 650 ? 36.030 87.236 -36.935 1.00 12.31 ? 650 LEU A C 1 ATOM 5254 O O . LEU A 1 650 ? 35.771 86.320 -36.151 1.00 12.61 ? 650 LEU A O 1 ATOM 5255 C CB . LEU A 1 650 ? 36.098 85.996 -39.084 1.00 11.88 ? 650 LEU A CB 1 ATOM 5256 C CG . LEU A 1 650 ? 34.648 86.324 -39.433 1.00 12.81 ? 650 LEU A CG 1 ATOM 5257 C CD1 . LEU A 1 650 ? 34.560 87.581 -40.308 1.00 14.12 ? 650 LEU A CD1 1 ATOM 5258 C CD2 . LEU A 1 650 ? 34.041 85.162 -40.201 1.00 16.03 ? 650 LEU A CD2 1 ATOM 5259 N N . LEU A 1 651 ? 35.665 88.488 -36.703 1.00 12.65 ? 651 LEU A N 1 ATOM 5260 C CA . LEU A 1 651 ? 34.877 88.894 -35.566 1.00 13.82 ? 651 LEU A CA 1 ATOM 5261 C C . LEU A 1 651 ? 33.442 89.112 -36.022 1.00 14.18 ? 651 LEU A C 1 ATOM 5262 O O . LEU A 1 651 ? 33.179 89.966 -36.890 1.00 15.24 ? 651 LEU A O 1 ATOM 5263 C CB . LEU A 1 651 ? 35.470 90.176 -35.002 1.00 15.34 ? 651 LEU A CB 1 ATOM 5264 C CG . LEU A 1 651 ? 35.228 90.567 -33.538 1.00 20.22 ? 651 LEU A CG 1 ATOM 5265 C CD1 . LEU A 1 651 ? 33.987 91.381 -33.351 1.00 25.96 ? 651 LEU A CD1 1 ATOM 5266 C CD2 . LEU A 1 651 ? 35.288 89.416 -32.545 1.00 19.97 ? 651 LEU A CD2 1 ATOM 5267 N N . LEU A 1 652 ? 32.507 88.342 -35.487 1.00 14.71 ? 652 LEU A N 1 ATOM 5268 C CA . LEU A 1 652 ? 31.108 88.415 -35.863 1.00 14.72 ? 652 LEU A CA 1 ATOM 5269 C C . LEU A 1 652 ? 30.338 89.144 -34.785 1.00 15.89 ? 652 LEU A C 1 ATOM 5270 O O . LEU A 1 652 ? 30.225 88.685 -33.636 1.00 15.60 ? 652 LEU A O 1 ATOM 5271 C CB . LEU A 1 652 ? 30.545 87.026 -36.140 1.00 14.77 ? 652 LEU A CB 1 ATOM 5272 C CG . LEU A 1 652 ? 31.281 86.296 -37.255 1.00 14.37 ? 652 LEU A CG 1 ATOM 5273 C CD1 . LEU A 1 652 ? 30.786 84.850 -37.353 1.00 16.81 ? 652 LEU A CD1 1 ATOM 5274 C CD2 . LEU A 1 652 ? 31.124 87.030 -38.623 1.00 15.63 ? 652 LEU A CD2 1 ATOM 5275 N N . ARG A 1 653 ? 29.840 90.330 -35.141 1.00 17.43 ? 653 ARG A N 1 ATOM 5276 C CA . ARG A 1 653 ? 29.064 91.174 -34.252 1.00 19.68 ? 653 ARG A CA 1 ATOM 5277 C C . ARG A 1 653 ? 28.551 92.343 -35.095 1.00 20.01 ? 653 ARG A C 1 ATOM 5278 O O . ARG A 1 653 ? 29.204 92.778 -36.032 1.00 20.55 ? 653 ARG A O 1 ATOM 5279 C CB . ARG A 1 653 ? 29.887 91.702 -33.070 1.00 20.65 ? 653 ARG A CB 1 ATOM 5280 C CG . ARG A 1 653 ? 31.043 92.588 -33.439 1.00 23.03 ? 653 ARG A CG 1 ATOM 5281 C CD . ARG A 1 653 ? 31.131 93.873 -32.626 1.00 30.58 ? 653 ARG A CD 1 ATOM 5282 N NE . ARG A 1 653 ? 31.271 93.717 -31.183 1.00 32.98 ? 653 ARG A NE 1 ATOM 5283 C CZ . ARG A 1 653 ? 30.902 94.631 -30.284 1.00 35.03 ? 653 ARG A CZ 1 ATOM 5284 N NH1 . ARG A 1 653 ? 30.333 95.769 -30.665 1.00 38.06 ? 653 ARG A NH1 1 ATOM 5285 N NH2 . ARG A 1 653 ? 31.070 94.408 -28.989 1.00 37.37 ? 653 ARG A NH2 1 ATOM 5286 N N . LYS A 1 654 ? 27.380 92.832 -34.747 1.00 22.33 ? 654 LYS A N 1 ATOM 5287 C CA . LYS A 1 654 ? 26.926 94.087 -35.322 1.00 24.76 ? 654 LYS A CA 1 ATOM 5288 C C . LYS A 1 654 ? 27.694 95.229 -34.639 1.00 25.49 ? 654 LYS A C 1 ATOM 5289 O O . LYS A 1 654 ? 28.118 95.090 -33.501 1.00 26.61 ? 654 LYS A O 1 ATOM 5290 C CB . LYS A 1 654 ? 25.418 94.209 -35.146 1.00 25.43 ? 654 LYS A CB 1 ATOM 5291 C CG . LYS A 1 654 ? 24.641 93.246 -36.046 1.00 28.20 ? 654 LYS A CG 1 ATOM 5292 C CD . LYS A 1 654 ? 23.496 93.939 -36.780 1.00 33.94 ? 654 LYS A CD 1 ATOM 5293 C CE . LYS A 1 654 ? 24.025 94.893 -37.860 1.00 36.55 ? 654 LYS A CE 1 ATOM 5294 N NZ . LYS A 1 654 ? 22.985 95.244 -38.875 1.00 38.80 ? 654 LYS A NZ 1 ATOM 5295 N N . ASN A 1 655 ? 27.911 96.329 -35.336 1.00 26.76 ? 655 ASN A N 1 ATOM 5296 C CA . ASN A 1 655 ? 28.558 97.476 -34.712 1.00 26.93 ? 655 ASN A CA 1 ATOM 5297 C C . ASN A 1 655 ? 29.992 97.172 -34.282 1.00 25.38 ? 655 ASN A C 1 ATOM 5298 O O . ASN A 1 655 ? 30.374 97.436 -33.154 1.00 26.49 ? 655 ASN A O 1 ATOM 5299 C CB . ASN A 1 655 ? 27.747 97.929 -33.495 1.00 28.09 ? 655 ASN A CB 1 ATOM 5300 C CG . ASN A 1 655 ? 28.182 99.280 -32.964 1.00 32.19 ? 655 ASN A CG 1 ATOM 5301 O OD1 . ASN A 1 655 ? 28.461 100.209 -33.729 1.00 35.93 ? 655 ASN A OD1 1 ATOM 5302 N ND2 . ASN A 1 655 ? 28.231 99.402 -31.645 1.00 35.96 ? 655 ASN A ND2 1 ATOM 5303 N N . PRO A 1 656 ? 30.786 96.612 -35.182 1.00 23.08 ? 656 PRO A N 1 ATOM 5304 C CA . PRO A 1 656 ? 32.164 96.279 -34.812 1.00 21.72 ? 656 PRO A CA 1 ATOM 5305 C C . PRO A 1 656 ? 32.998 97.543 -34.751 1.00 20.68 ? 656 PRO A C 1 ATOM 5306 O O . PRO A 1 656 ? 32.657 98.564 -35.371 1.00 19.57 ? 656 PRO A O 1 ATOM 5307 C CB . PRO A 1 656 ? 32.633 95.401 -35.964 1.00 21.60 ? 656 PRO A CB 1 ATOM 5308 C CG . PRO A 1 656 ? 31.852 95.889 -37.129 1.00 21.54 ? 656 PRO A CG 1 ATOM 5309 C CD . PRO A 1 656 ? 30.491 96.251 -36.584 1.00 22.84 ? 656 PRO A CD 1 ATOM 5310 N N . THR A 1 657 ? 34.074 97.471 -33.991 1.00 19.91 ? 657 THR A N 1 ATOM 5311 C CA . THR A 1 657 ? 35.119 98.473 -34.058 1.00 19.93 ? 657 THR A CA 1 ATOM 5312 C C . THR A 1 657 ? 36.406 97.736 -34.405 1.00 18.94 ? 657 THR A C 1 ATOM 5313 O O . THR A 1 657 ? 36.488 96.494 -34.284 1.00 19.31 ? 657 THR A O 1 ATOM 5314 C CB . THR A 1 657 ? 35.275 99.197 -32.715 1.00 20.44 ? 657 THR A CB 1 ATOM 5315 O OG1 . THR A 1 657 ? 35.254 98.233 -31.653 1.00 23.22 ? 657 THR A OG1 1 ATOM 5316 C CG2 . THR A 1 657 ? 34.065 100.084 -32.430 1.00 21.44 ? 657 THR A CG2 1 ATOM 5317 N N . SER A 1 658 ? 37.419 98.491 -34.796 1.00 18.05 ? 658 SER A N 1 ATOM 5318 C CA . SER A 1 658 ? 38.662 97.922 -35.292 1.00 18.44 ? 658 SER A CA 1 ATOM 5319 C C . SER A 1 658 ? 39.402 97.093 -34.229 1.00 18.81 ? 658 SER A C 1 ATOM 5320 O O . SER A 1 658 ? 39.168 97.251 -33.020 1.00 19.00 ? 658 SER A O 1 ATOM 5321 C CB . SER A 1 658 ? 39.574 99.049 -35.714 1.00 18.89 ? 658 SER A CB 1 ATOM 5322 O OG . SER A 1 658 ? 39.903 99.797 -34.552 1.00 20.25 ? 658 SER A OG 1 ATOM 5323 N N . LEU A 1 659 ? 40.291 96.223 -34.700 1.00 18.52 ? 659 LEU A N 1 ATOM 5324 C CA . LEU A 1 659 ? 41.076 95.357 -33.818 1.00 18.76 ? 659 LEU A CA 1 ATOM 5325 C C . LEU A 1 659 ? 42.487 95.276 -34.368 1.00 19.38 ? 659 LEU A C 1 ATOM 5326 O O . LEU A 1 659 ? 42.823 94.339 -35.091 1.00 18.46 ? 659 LEU A O 1 ATOM 5327 C CB . LEU A 1 659 ? 40.451 93.952 -33.753 1.00 19.74 ? 659 LEU A CB 1 ATOM 5328 C CG . LEU A 1 659 ? 39.118 93.778 -33.019 1.00 20.34 ? 659 LEU A CG 1 ATOM 5329 C CD1 . LEU A 1 659 ? 38.535 92.385 -33.297 1.00 21.62 ? 659 LEU A CD1 1 ATOM 5330 C CD2 . LEU A 1 659 ? 39.255 94.039 -31.526 1.00 22.82 ? 659 LEU A CD2 1 ATOM 5331 N N . PRO A 1 660 ? 43.304 96.288 -34.071 1.00 19.93 ? 660 PRO A N 1 ATOM 5332 C CA . PRO A 1 660 ? 44.687 96.298 -34.546 1.00 19.76 ? 660 PRO A CA 1 ATOM 5333 C C . PRO A 1 660 ? 45.503 95.194 -33.862 1.00 19.39 ? 660 PRO A C 1 ATOM 5334 O O . PRO A 1 660 ? 45.210 94.845 -32.723 1.00 19.35 ? 660 PRO A O 1 ATOM 5335 C CB . PRO A 1 660 ? 45.199 97.683 -34.119 1.00 20.63 ? 660 PRO A CB 1 ATOM 5336 C CG . PRO A 1 660 ? 44.318 98.128 -33.023 1.00 21.17 ? 660 PRO A CG 1 ATOM 5337 C CD . PRO A 1 660 ? 42.978 97.482 -33.268 1.00 20.40 ? 660 PRO A CD 1 ATOM 5338 N N . LEU A 1 661 ? 46.512 94.686 -34.547 1.00 20.06 ? 661 LEU A N 1 ATOM 5339 C CA . LEU A 1 661 ? 47.254 93.536 -34.016 1.00 19.78 ? 661 LEU A CA 1 ATOM 5340 C C . LEU A 1 661 ? 48.788 93.679 -34.071 1.00 21.13 ? 661 LEU A C 1 ATOM 5341 O O . LEU A 1 661 ? 49.509 92.690 -34.260 1.00 19.86 ? 661 LEU A O 1 ATOM 5342 C CB . LEU A 1 661 ? 46.802 92.264 -34.739 1.00 19.63 ? 661 LEU A CB 1 ATOM 5343 C CG . LEU A 1 661 ? 45.381 91.775 -34.445 1.00 17.18 ? 661 LEU A CG 1 ATOM 5344 C CD1 . LEU A 1 661 ? 45.122 90.528 -35.300 1.00 17.03 ? 661 LEU A CD1 1 ATOM 5345 C CD2 . LEU A 1 661 ? 45.245 91.467 -32.962 1.00 17.73 ? 661 LEU A CD2 1 ATOM 5346 N N . GLY A 1 662 ? 49.290 94.908 -33.935 1.00 22.64 ? 662 GLY A N 1 ATOM 5347 C CA . GLY A 1 662 ? 50.724 95.160 -34.078 1.00 22.88 ? 662 GLY A CA 1 ATOM 5348 C C . GLY A 1 662 ? 51.287 94.680 -35.404 1.00 23.31 ? 662 GLY A C 1 ATOM 5349 O O . GLY A 1 662 ? 50.744 94.981 -36.467 1.00 23.98 ? 662 GLY A O 1 ATOM 5350 N N . GLN A 1 663 ? 52.352 93.877 -35.344 1.00 23.40 ? 663 GLN A N 1 ATOM 5351 C CA . GLN A 1 663 ? 53.001 93.380 -36.562 1.00 23.72 ? 663 GLN A CA 1 ATOM 5352 C C . GLN A 1 663 ? 52.310 92.199 -37.232 1.00 22.32 ? 663 GLN A C 1 ATOM 5353 O O . GLN A 1 663 ? 52.756 91.732 -38.278 1.00 23.58 ? 663 GLN A O 1 ATOM 5354 C CB . GLN A 1 663 ? 54.441 92.937 -36.298 1.00 24.82 ? 663 GLN A CB 1 ATOM 5355 C CG . GLN A 1 663 ? 55.305 93.854 -35.460 1.00 28.09 ? 663 GLN A CG 1 ATOM 5356 C CD . GLN A 1 663 ? 56.555 93.119 -35.025 1.00 30.35 ? 663 GLN A CD 1 ATOM 5357 O OE1 . GLN A 1 663 ? 57.450 92.898 -35.846 1.00 30.76 ? 663 GLN A OE1 1 ATOM 5358 N NE2 . GLN A 1 663 ? 56.602 92.691 -33.754 1.00 31.81 ? 663 GLN A NE2 1 ATOM 5359 N N . TYR A 1 664 ? 51.236 91.697 -36.628 1.00 22.09 ? 664 TYR A N 1 ATOM 5360 C CA . TYR A 1 664 ? 50.575 90.509 -37.168 1.00 20.61 ? 664 TYR A CA 1 ATOM 5361 C C . TYR A 1 664 ? 50.184 90.745 -38.634 1.00 20.86 ? 664 TYR A C 1 ATOM 5362 O O . TYR A 1 664 ? 49.538 91.751 -38.933 1.00 22.05 ? 664 TYR A O 1 ATOM 5363 C CB . TYR A 1 664 ? 49.369 90.191 -36.291 1.00 18.88 ? 664 TYR A CB 1 ATOM 5364 C CG . TYR A 1 664 ? 48.765 88.849 -36.579 1.00 17.24 ? 664 TYR A CG 1 ATOM 5365 C CD1 . TYR A 1 664 ? 49.313 87.689 -36.018 1.00 14.59 ? 664 TYR A CD1 1 ATOM 5366 C CD2 . TYR A 1 664 ? 47.629 88.739 -37.379 1.00 15.02 ? 664 TYR A CD2 1 ATOM 5367 C CE1 . TYR A 1 664 ? 48.755 86.454 -36.285 1.00 14.53 ? 664 TYR A CE1 1 ATOM 5368 C CE2 . TYR A 1 664 ? 47.060 87.504 -37.649 1.00 17.08 ? 664 TYR A CE2 1 ATOM 5369 C CZ . TYR A 1 664 ? 47.637 86.360 -37.091 1.00 14.42 ? 664 TYR A CZ 1 ATOM 5370 O OH . TYR A 1 664 ? 47.066 85.135 -37.329 1.00 14.94 ? 664 TYR A OH 1 ATOM 5371 N N . PRO A 1 665 ? 50.622 89.884 -39.549 1.00 21.44 ? 665 PRO A N 1 ATOM 5372 C CA . PRO A 1 665 ? 50.499 90.165 -40.991 1.00 21.62 ? 665 PRO A CA 1 ATOM 5373 C C . PRO A 1 665 ? 49.122 90.072 -41.671 1.00 22.03 ? 665 PRO A C 1 ATOM 5374 O O . PRO A 1 665 ? 49.032 90.408 -42.855 1.00 23.60 ? 665 PRO A O 1 ATOM 5375 C CB . PRO A 1 665 ? 51.468 89.161 -41.632 1.00 21.99 ? 665 PRO A CB 1 ATOM 5376 C CG . PRO A 1 665 ? 51.552 88.051 -40.639 1.00 21.71 ? 665 PRO A CG 1 ATOM 5377 C CD . PRO A 1 665 ? 51.398 88.658 -39.295 1.00 21.14 ? 665 PRO A CD 1 ATOM 5378 N N A GLU A 1 666 ? 48.088 89.644 -40.954 0.50 21.26 ? 666 GLU A N 1 ATOM 5379 N N B GLU A 1 666 ? 48.098 89.592 -40.965 0.50 21.26 ? 666 GLU A N 1 ATOM 5380 C CA A GLU A 1 666 ? 46.770 89.425 -41.553 0.50 20.60 ? 666 GLU A CA 1 ATOM 5381 C CA B GLU A 1 666 ? 46.757 89.444 -41.541 0.50 20.63 ? 666 GLU A CA 1 ATOM 5382 C C A GLU A 1 666 ? 45.750 90.285 -40.812 0.50 19.75 ? 666 GLU A C 1 ATOM 5383 C C B GLU A 1 666 ? 45.801 90.351 -40.796 0.50 19.81 ? 666 GLU A C 1 ATOM 5384 O O A GLU A 1 666 ? 45.624 90.188 -39.592 0.50 18.72 ? 666 GLU A O 1 ATOM 5385 O O B GLU A 1 666 ? 45.757 90.337 -39.563 0.50 18.82 ? 666 GLU A O 1 ATOM 5386 C CB A GLU A 1 666 ? 46.438 87.933 -41.468 0.50 21.09 ? 666 GLU A CB 1 ATOM 5387 C CB B GLU A 1 666 ? 46.281 87.995 -41.438 0.50 21.16 ? 666 GLU A CB 1 ATOM 5388 C CG A GLU A 1 666 ? 44.980 87.560 -41.650 0.50 22.53 ? 666 GLU A CG 1 ATOM 5389 C CG B GLU A 1 666 ? 47.131 86.998 -42.210 0.50 22.53 ? 666 GLU A CG 1 ATOM 5390 C CD A GLU A 1 666 ? 44.596 87.229 -43.081 0.50 23.95 ? 666 GLU A CD 1 ATOM 5391 C CD B GLU A 1 666 ? 46.958 87.132 -43.711 0.50 24.83 ? 666 GLU A CD 1 ATOM 5392 O OE1 A GLU A 1 666 ? 45.350 87.588 -44.019 0.50 26.29 ? 666 GLU A OE1 1 ATOM 5393 O OE1 B GLU A 1 666 ? 45.912 86.697 -44.230 0.50 27.02 ? 666 GLU A OE1 1 ATOM 5394 O OE2 A GLU A 1 666 ? 43.521 86.618 -43.267 0.50 22.05 ? 666 GLU A OE2 1 ATOM 5395 O OE2 B GLU A 1 666 ? 47.871 87.669 -44.370 0.50 27.49 ? 666 GLU A OE2 1 ATOM 5396 N N . ASP A 1 667 ? 45.043 91.155 -41.539 1.00 18.73 ? 667 ASP A N 1 ATOM 5397 C CA . ASP A 1 667 ? 44.071 92.060 -40.914 1.00 17.89 ? 667 ASP A CA 1 ATOM 5398 C C . ASP A 1 667 ? 42.836 91.269 -40.436 1.00 14.71 ? 667 ASP A C 1 ATOM 5399 O O . ASP A 1 667 ? 42.354 90.421 -41.164 1.00 14.91 ? 667 ASP A O 1 ATOM 5400 C CB . ASP A 1 667 ? 43.570 93.111 -41.936 1.00 18.96 ? 667 ASP A CB 1 ATOM 5401 C CG . ASP A 1 667 ? 44.650 94.103 -42.355 1.00 23.10 ? 667 ASP A CG 1 ATOM 5402 O OD1 . ASP A 1 667 ? 45.691 94.229 -41.658 1.00 28.21 ? 667 ASP A OD1 1 ATOM 5403 O OD2 . ASP A 1 667 ? 44.520 94.837 -43.367 1.00 27.36 ? 667 ASP A OD2 1 ATOM 5404 N N . VAL A 1 668 ? 42.315 91.607 -39.271 1.00 14.40 ? 668 VAL A N 1 ATOM 5405 C CA . VAL A 1 668 ? 41.045 91.032 -38.774 1.00 15.05 ? 668 VAL A CA 1 ATOM 5406 C C . VAL A 1 668 ? 39.911 91.419 -39.709 1.00 14.56 ? 668 VAL A C 1 ATOM 5407 O O . VAL A 1 668 ? 39.877 92.587 -40.171 1.00 15.62 ? 668 VAL A O 1 ATOM 5408 C CB . VAL A 1 668 ? 40.691 91.497 -37.340 1.00 15.15 ? 668 VAL A CB 1 ATOM 5409 C CG1 . VAL A 1 668 ? 39.349 90.973 -36.891 1.00 15.37 ? 668 VAL A CG1 1 ATOM 5410 C CG2 . VAL A 1 668 ? 41.767 91.079 -36.357 1.00 15.57 ? 668 VAL A CG2 1 ATOM 5411 N N . LYS A 1 669 ? 39.034 90.466 -40.001 1.00 13.11 ? 669 LYS A N 1 ATOM 5412 C CA . LYS A 1 669 ? 37.806 90.643 -40.801 1.00 14.38 ? 669 LYS A CA 1 ATOM 5413 C C . LYS A 1 669 ? 36.593 90.728 -39.876 1.00 13.61 ? 669 LYS A C 1 ATOM 5414 O O . LYS A 1 669 ? 36.600 90.168 -38.756 1.00 13.23 ? 669 LYS A O 1 ATOM 5415 C CB . LYS A 1 669 ? 37.640 89.462 -41.753 1.00 16.49 ? 669 LYS A CB 1 ATOM 5416 C CG . LYS A 1 669 ? 38.388 89.580 -43.075 1.00 22.90 ? 669 LYS A CG 1 ATOM 5417 C CD . LYS A 1 669 ? 39.889 89.360 -42.959 1.00 28.24 ? 669 LYS A CD 1 ATOM 5418 C CE . LYS A 1 669 ? 40.621 89.946 -44.187 1.00 29.89 ? 669 LYS A CE 1 ATOM 5419 N NZ . LYS A 1 669 ? 42.075 90.159 -43.933 1.00 30.53 ? 669 LYS A NZ 1 ATOM 5420 N N . PHE A 1 670 ? 35.538 91.402 -40.337 1.00 13.42 ? 670 PHE A N 1 ATOM 5421 C CA . PHE A 1 670 ? 34.334 91.641 -39.547 1.00 13.78 ? 670 PHE A CA 1 ATOM 5422 C C . PHE A 1 670 ? 33.100 91.180 -40.314 1.00 14.65 ? 670 PHE A C 1 ATOM 5423 O O . PHE A 1 670 ? 33.101 91.184 -41.537 1.00 15.41 ? 670 PHE A O 1 ATOM 5424 C CB . PHE A 1 670 ? 34.226 93.135 -39.135 1.00 14.76 ? 670 PHE A CB 1 ATOM 5425 C CG . PHE A 1 670 ? 35.386 93.591 -38.323 1.00 14.62 ? 670 PHE A CG 1 ATOM 5426 C CD1 . PHE A 1 670 ? 36.528 94.068 -38.962 1.00 16.40 ? 670 PHE A CD1 1 ATOM 5427 C CD2 . PHE A 1 670 ? 35.384 93.466 -36.937 1.00 17.15 ? 670 PHE A CD2 1 ATOM 5428 C CE1 . PHE A 1 670 ? 37.636 94.458 -38.230 1.00 16.87 ? 670 PHE A CE1 1 ATOM 5429 C CE2 . PHE A 1 670 ? 36.492 93.853 -36.201 1.00 18.27 ? 670 PHE A CE2 1 ATOM 5430 C CZ . PHE A 1 670 ? 37.620 94.361 -36.865 1.00 17.79 ? 670 PHE A CZ 1 ATOM 5431 N N . GLY A 1 671 ? 32.048 90.780 -39.606 1.00 15.21 ? 671 GLY A N 1 ATOM 5432 C CA . GLY A 1 671 ? 30.789 90.444 -40.242 1.00 15.19 ? 671 GLY A CA 1 ATOM 5433 C C . GLY A 1 671 ? 29.668 90.444 -39.243 1.00 15.77 ? 671 GLY A C 1 ATOM 5434 O O . GLY A 1 671 ? 29.886 90.451 -38.029 1.00 14.68 ? 671 GLY A O 1 ATOM 5435 N N . ASP A 1 672 ? 28.439 90.445 -39.757 1.00 15.77 ? 672 ASP A N 1 ATOM 5436 C CA . ASP A 1 672 ? 27.280 90.267 -38.885 1.00 17.54 ? 672 ASP A CA 1 ATOM 5437 C C . ASP A 1 672 ? 27.270 88.800 -38.418 1.00 16.85 ? 672 ASP A C 1 ATOM 5438 O O . ASP A 1 672 ? 27.749 87.931 -39.149 1.00 16.28 ? 672 ASP A O 1 ATOM 5439 C CB . ASP A 1 672 ? 25.961 90.508 -39.629 1.00 18.43 ? 672 ASP A CB 1 ATOM 5440 C CG . ASP A 1 672 ? 25.670 91.972 -39.869 1.00 22.94 ? 672 ASP A CG 1 ATOM 5441 O OD1 . ASP A 1 672 ? 26.281 92.848 -39.219 1.00 24.77 ? 672 ASP A OD1 1 ATOM 5442 O OD2 . ASP A 1 672 ? 24.791 92.320 -40.694 1.00 28.52 ? 672 ASP A OD2 1 ATOM 5443 N N . PRO A 1 673 ? 26.702 88.528 -37.232 1.00 17.63 ? 673 PRO A N 1 ATOM 5444 C CA . PRO A 1 673 ? 26.551 87.129 -36.785 1.00 18.36 ? 673 PRO A CA 1 ATOM 5445 C C . PRO A 1 673 ? 25.940 86.257 -37.877 1.00 18.29 ? 673 PRO A C 1 ATOM 5446 O O . PRO A 1 673 ? 25.011 86.688 -38.585 1.00 19.11 ? 673 PRO A O 1 ATOM 5447 C CB . PRO A 1 673 ? 25.632 87.243 -35.578 1.00 18.90 ? 673 PRO A CB 1 ATOM 5448 C CG . PRO A 1 673 ? 25.936 88.600 -35.005 1.00 19.87 ? 673 PRO A CG 1 ATOM 5449 C CD . PRO A 1 673 ? 26.218 89.480 -36.211 1.00 18.46 ? 673 PRO A CD 1 ATOM 5450 N N . ARG A 1 674 ? 26.464 85.050 -38.019 1.00 17.53 ? 674 ARG A N 1 ATOM 5451 C CA . ARG A 1 674 ? 26.011 84.113 -39.046 1.00 18.18 ? 674 ARG A CA 1 ATOM 5452 C C . ARG A 1 674 ? 26.475 82.710 -38.682 1.00 18.25 ? 674 ARG A C 1 ATOM 5453 O O . ARG A 1 674 ? 27.451 82.553 -37.955 1.00 17.91 ? 674 ARG A O 1 ATOM 5454 C CB . ARG A 1 674 ? 26.554 84.502 -40.429 1.00 18.04 ? 674 ARG A CB 1 ATOM 5455 C CG . ARG A 1 674 ? 28.071 84.421 -40.627 1.00 19.04 ? 674 ARG A CG 1 ATOM 5456 C CD . ARG A 1 674 ? 28.443 84.585 -42.094 1.00 20.20 ? 674 ARG A CD 1 ATOM 5457 N NE . ARG A 1 674 ? 29.818 84.239 -42.433 1.00 23.65 ? 674 ARG A NE 1 ATOM 5458 C CZ . ARG A 1 674 ? 30.805 85.111 -42.571 1.00 24.62 ? 674 ARG A CZ 1 ATOM 5459 N NH1 . ARG A 1 674 ? 30.592 86.414 -42.383 1.00 26.12 ? 674 ARG A NH1 1 ATOM 5460 N NH2 . ARG A 1 674 ? 32.016 84.678 -42.900 1.00 25.43 ? 674 ARG A NH2 1 ATOM 5461 N N . GLU A 1 675 ? 25.789 81.693 -39.183 1.00 18.08 ? 675 GLU A N 1 ATOM 5462 C CA . GLU A 1 675 ? 26.295 80.340 -39.043 1.00 18.48 ? 675 GLU A CA 1 ATOM 5463 C C . GLU A 1 675 ? 27.617 80.147 -39.775 1.00 19.17 ? 675 GLU A C 1 ATOM 5464 O O . GLU A 1 675 ? 27.866 80.737 -40.843 1.00 20.38 ? 675 GLU A O 1 ATOM 5465 C CB . GLU A 1 675 ? 25.234 79.352 -39.513 1.00 19.82 ? 675 GLU A CB 1 ATOM 5466 C CG . GLU A 1 675 ? 23.979 79.532 -38.703 1.00 22.64 ? 675 GLU A CG 1 ATOM 5467 C CD . GLU A 1 675 ? 23.096 78.310 -38.726 1.00 28.92 ? 675 GLU A CD 1 ATOM 5468 O OE1 . GLU A 1 675 ? 23.244 77.513 -39.683 1.00 31.75 ? 675 GLU A OE1 1 ATOM 5469 O OE2 . GLU A 1 675 ? 22.276 78.145 -37.778 1.00 31.53 ? 675 GLU A OE2 1 ATOM 5470 N N . ILE A 1 676 ? 28.507 79.346 -39.200 1.00 18.64 ? 676 ILE A N 1 ATOM 5471 C CA . ILE A 1 676 ? 29.760 79.067 -39.874 1.00 19.35 ? 676 ILE A CA 1 ATOM 5472 C C . ILE A 1 676 ? 30.130 77.592 -39.734 1.00 17.98 ? 676 ILE A C 1 ATOM 5473 O O . ILE A 1 676 ? 29.624 76.908 -38.831 1.00 17.79 ? 676 ILE A O 1 ATOM 5474 C CB . ILE A 1 676 ? 30.904 79.936 -39.350 1.00 20.91 ? 676 ILE A CB 1 ATOM 5475 C CG1 . ILE A 1 676 ? 31.106 79.718 -37.871 1.00 20.50 ? 676 ILE A CG1 1 ATOM 5476 C CG2 . ILE A 1 676 ? 30.751 81.449 -39.710 1.00 23.81 ? 676 ILE A CG2 1 ATOM 5477 C CD1 . ILE A 1 676 ? 32.565 79.526 -37.558 1.00 25.77 ? 676 ILE A CD1 1 ATOM 5478 N N . SER A 1 677 ? 31.005 77.138 -40.619 1.00 17.12 ? 677 SER A N 1 ATOM 5479 C CA A SER A 1 677 ? 31.522 75.766 -40.656 0.50 17.51 ? 677 SER A CA 1 ATOM 5480 C CA B SER A 1 677 ? 31.548 75.780 -40.535 0.50 17.43 ? 677 SER A CA 1 ATOM 5481 C C . SER A 1 677 ? 33.056 75.800 -40.669 1.00 17.64 ? 677 SER A C 1 ATOM 5482 O O . SER A 1 677 ? 33.643 76.658 -41.342 1.00 18.12 ? 677 SER A O 1 ATOM 5483 C CB A SER A 1 677 ? 30.989 75.072 -41.931 0.50 17.88 ? 677 SER A CB 1 ATOM 5484 C CB B SER A 1 677 ? 30.919 74.847 -41.583 0.50 17.74 ? 677 SER A CB 1 ATOM 5485 O OG A SER A 1 677 ? 31.647 73.856 -42.203 0.50 19.37 ? 677 SER A OG 1 ATOM 5486 O OG B SER A 1 677 ? 29.530 74.752 -41.376 0.50 19.72 ? 677 SER A OG 1 ATOM 5487 N N . LEU A 1 678 ? 33.708 74.861 -39.985 1.00 16.26 ? 678 LEU A N 1 ATOM 5488 C CA . LEU A 1 678 ? 35.156 74.783 -39.972 1.00 16.19 ? 678 LEU A CA 1 ATOM 5489 C C . LEU A 1 678 ? 35.600 73.343 -40.099 1.00 16.04 ? 678 LEU A C 1 ATOM 5490 O O . LEU A 1 678 ? 34.898 72.446 -39.612 1.00 15.90 ? 678 LEU A O 1 ATOM 5491 C CB . LEU A 1 678 ? 35.713 75.328 -38.658 1.00 16.65 ? 678 LEU A CB 1 ATOM 5492 C CG . LEU A 1 678 ? 35.827 76.828 -38.477 1.00 17.40 ? 678 LEU A CG 1 ATOM 5493 C CD1 . LEU A 1 678 ? 36.168 77.065 -37.022 1.00 20.69 ? 678 LEU A CD1 1 ATOM 5494 C CD2 . LEU A 1 678 ? 36.942 77.382 -39.332 1.00 20.17 ? 678 LEU A CD2 1 ATOM 5495 N N . ARG A 1 679 ? 36.734 73.140 -40.736 1.00 15.78 ? 679 ARG A N 1 ATOM 5496 C CA . ARG A 1 679 ? 37.375 71.829 -40.808 1.00 18.07 ? 679 ARG A CA 1 ATOM 5497 C C . ARG A 1 679 ? 38.882 72.046 -40.775 1.00 18.11 ? 679 ARG A C 1 ATOM 5498 O O . ARG A 1 679 ? 39.421 72.844 -41.560 1.00 18.99 ? 679 ARG A O 1 ATOM 5499 C CB . ARG A 1 679 ? 36.973 71.109 -42.099 1.00 19.20 ? 679 ARG A CB 1 ATOM 5500 C CG . ARG A 1 679 ? 37.467 69.685 -42.164 1.00 21.41 ? 679 ARG A CG 1 ATOM 5501 C CD . ARG A 1 679 ? 37.251 69.047 -43.525 1.00 25.68 ? 679 ARG A CD 1 ATOM 5502 N NE . ARG A 1 679 ? 37.649 67.647 -43.488 1.00 30.94 ? 679 ARG A NE 1 ATOM 5503 C CZ . ARG A 1 679 ? 37.781 66.865 -44.553 1.00 33.73 ? 679 ARG A CZ 1 ATOM 5504 N NH1 . ARG A 1 679 ? 37.553 67.334 -45.775 1.00 35.66 ? 679 ARG A NH1 1 ATOM 5505 N NH2 . ARG A 1 679 ? 38.146 65.604 -44.387 1.00 36.55 ? 679 ARG A NH2 1 ATOM 5506 N N . VAL A 1 680 ? 39.560 71.374 -39.852 1.00 17.23 ? 680 VAL A N 1 ATOM 5507 C CA . VAL A 1 680 ? 40.999 71.353 -39.812 1.00 17.76 ? 680 VAL A CA 1 ATOM 5508 C C . VAL A 1 680 ? 41.530 70.001 -40.282 1.00 19.55 ? 680 VAL A C 1 ATOM 5509 O O . VAL A 1 680 ? 40.999 68.950 -39.887 1.00 19.22 ? 680 VAL A O 1 ATOM 5510 C CB . VAL A 1 680 ? 41.520 71.642 -38.382 1.00 17.09 ? 680 VAL A CB 1 ATOM 5511 C CG1 . VAL A 1 680 ? 43.013 71.404 -38.304 1.00 17.11 ? 680 VAL A CG1 1 ATOM 5512 C CG2 . VAL A 1 680 ? 41.142 73.085 -37.948 1.00 15.80 ? 680 VAL A CG2 1 ATOM 5513 N N . GLY A 1 681 ? 42.554 70.046 -41.136 1.00 20.78 ? 681 GLY A N 1 ATOM 5514 C CA . GLY A 1 681 ? 43.125 68.839 -41.731 1.00 23.61 ? 681 GLY A CA 1 ATOM 5515 C C . GLY A 1 681 ? 42.063 67.979 -42.406 1.00 24.78 ? 681 GLY A C 1 ATOM 5516 O O . GLY A 1 681 ? 41.137 68.498 -43.046 1.00 25.77 ? 681 GLY A O 1 ATOM 5517 N N . ASN A 1 682 ? 42.189 66.661 -42.254 1.00 27.23 ? 682 ASN A N 1 ATOM 5518 C CA . ASN A 1 682 ? 41.176 65.738 -42.784 1.00 28.36 ? 682 ASN A CA 1 ATOM 5519 C C . ASN A 1 682 ? 40.199 65.311 -41.687 1.00 28.08 ? 682 ASN A C 1 ATOM 5520 O O . ASN A 1 682 ? 39.514 64.291 -41.788 1.00 29.18 ? 682 ASN A O 1 ATOM 5521 C CB . ASN A 1 682 ? 41.815 64.533 -43.495 1.00 29.67 ? 682 ASN A CB 1 ATOM 5522 C CG . ASN A 1 682 ? 42.834 63.802 -42.629 1.00 32.72 ? 682 ASN A CG 1 ATOM 5523 O OD1 . ASN A 1 682 ? 42.679 63.686 -41.403 1.00 37.46 ? 682 ASN A OD1 1 ATOM 5524 N ND2 . ASN A 1 682 ? 43.882 63.291 -43.268 1.00 35.90 ? 682 ASN A ND2 1 ATOM 5525 N N . GLY A 1 683 ? 40.111 66.137 -40.651 1.00 26.72 ? 683 GLY A N 1 ATOM 5526 C CA . GLY A 1 683 ? 39.305 65.834 -39.494 1.00 24.35 ? 683 GLY A CA 1 ATOM 5527 C C . GLY A 1 683 ? 37.838 66.146 -39.697 1.00 22.45 ? 683 GLY A C 1 ATOM 5528 O O . GLY A 1 683 ? 37.391 66.352 -40.827 1.00 22.77 ? 683 GLY A O 1 ATOM 5529 N N . PRO A 1 684 ? 37.076 66.205 -38.607 1.00 20.31 ? 684 PRO A N 1 ATOM 5530 C CA . PRO A 1 684 ? 35.636 66.446 -38.735 1.00 19.45 ? 684 PRO A CA 1 ATOM 5531 C C . PRO A 1 684 ? 35.323 67.892 -39.156 1.00 18.15 ? 684 PRO A C 1 ATOM 5532 O O . PRO A 1 684 ? 36.158 68.774 -38.974 1.00 17.63 ? 684 PRO A O 1 ATOM 5533 C CB . PRO A 1 684 ? 35.093 66.170 -37.325 1.00 19.20 ? 684 PRO A CB 1 ATOM 5534 C CG . PRO A 1 684 ? 36.286 66.385 -36.399 1.00 20.05 ? 684 PRO A CG 1 ATOM 5535 C CD . PRO A 1 684 ? 37.504 66.072 -37.203 1.00 20.94 ? 684 PRO A CD 1 ATOM 5536 N N . THR A 1 685 ? 34.145 68.094 -39.718 1.00 17.30 ? 685 THR A N 1 ATOM 5537 C CA . THR A 1 685 ? 33.651 69.418 -40.069 1.00 16.53 ? 685 THR A CA 1 ATOM 5538 C C . THR A 1 685 ? 32.620 69.771 -39.023 1.00 16.43 ? 685 THR A C 1 ATOM 5539 O O . THR A 1 685 ? 31.677 69.018 -38.797 1.00 16.47 ? 685 THR A O 1 ATOM 5540 C CB . THR A 1 685 ? 33.032 69.411 -41.495 1.00 17.65 ? 685 THR A CB 1 ATOM 5541 O OG1 . THR A 1 685 ? 34.060 69.113 -42.433 1.00 18.94 ? 685 THR A OG1 1 ATOM 5542 C CG2 . THR A 1 685 ? 32.548 70.802 -41.888 1.00 18.88 ? 685 THR A CG2 1 ATOM 5543 N N . LEU A 1 686 ? 32.801 70.919 -38.362 1.00 13.84 ? 686 LEU A N 1 ATOM 5544 C CA . LEU A 1 686 ? 31.906 71.350 -37.308 1.00 14.20 ? 686 LEU A CA 1 ATOM 5545 C C . LEU A 1 686 ? 31.111 72.556 -37.787 1.00 13.31 ? 686 LEU A C 1 ATOM 5546 O O . LEU A 1 686 ? 31.701 73.503 -38.337 1.00 13.63 ? 686 LEU A O 1 ATOM 5547 C CB . LEU A 1 686 ? 32.687 71.746 -36.036 1.00 13.20 ? 686 LEU A CB 1 ATOM 5548 C CG . LEU A 1 686 ? 33.681 70.784 -35.366 1.00 19.37 ? 686 LEU A CG 1 ATOM 5549 C CD1 . LEU A 1 686 ? 33.819 71.133 -33.888 1.00 18.82 ? 686 LEU A CD1 1 ATOM 5550 C CD2 . LEU A 1 686 ? 33.446 69.320 -35.551 1.00 17.86 ? 686 LEU A CD2 1 ATOM 5551 N N . ALA A 1 687 ? 29.822 72.548 -37.542 1.00 13.04 ? 687 ALA A N 1 ATOM 5552 C CA . ALA A 1 687 ? 28.983 73.701 -37.847 1.00 13.13 ? 687 ALA A CA 1 ATOM 5553 C C . ALA A 1 687 ? 28.531 74.369 -36.563 1.00 13.90 ? 687 ALA A C 1 ATOM 5554 O O . ALA A 1 687 ? 28.207 73.677 -35.570 1.00 13.99 ? 687 ALA A O 1 ATOM 5555 C CB . ALA A 1 687 ? 27.754 73.258 -38.672 1.00 14.09 ? 687 ALA A CB 1 ATOM 5556 N N . PHE A 1 688 ? 28.464 75.705 -36.567 1.00 13.40 ? 688 PHE A N 1 ATOM 5557 C CA . PHE A 1 688 ? 28.135 76.510 -35.405 1.00 12.84 ? 688 PHE A CA 1 ATOM 5558 C C . PHE A 1 688 ? 26.964 77.417 -35.680 1.00 13.70 ? 688 PHE A C 1 ATOM 5559 O O . PHE A 1 688 ? 26.823 77.937 -36.825 1.00 14.50 ? 688 PHE A O 1 ATOM 5560 C CB . PHE A 1 688 ? 29.333 77.380 -35.000 1.00 13.11 ? 688 PHE A CB 1 ATOM 5561 C CG . PHE A 1 688 ? 30.553 76.571 -34.659 1.00 10.82 ? 688 PHE A CG 1 ATOM 5562 C CD1 . PHE A 1 688 ? 31.406 76.108 -35.632 1.00 12.30 ? 688 PHE A CD1 1 ATOM 5563 C CD2 . PHE A 1 688 ? 30.837 76.295 -33.319 1.00 12.03 ? 688 PHE A CD2 1 ATOM 5564 C CE1 . PHE A 1 688 ? 32.522 75.350 -35.313 1.00 11.50 ? 688 PHE A CE1 1 ATOM 5565 C CE2 . PHE A 1 688 ? 31.948 75.557 -32.995 1.00 12.07 ? 688 PHE A CE2 1 ATOM 5566 C CZ . PHE A 1 688 ? 32.787 75.080 -33.965 1.00 10.99 ? 688 PHE A CZ 1 ATOM 5567 N N . SER A 1 689 ? 26.143 77.632 -34.676 1.00 14.21 ? 689 SER A N 1 ATOM 5568 C CA . SER A 1 689 ? 25.042 78.608 -34.738 1.00 14.57 ? 689 SER A CA 1 ATOM 5569 C C . SER A 1 689 ? 25.592 80.039 -34.828 1.00 14.87 ? 689 SER A C 1 ATOM 5570 O O . SER A 1 689 ? 26.774 80.305 -34.582 1.00 13.94 ? 689 SER A O 1 ATOM 5571 C CB . SER A 1 689 ? 24.169 78.520 -33.491 1.00 15.45 ? 689 SER A CB 1 ATOM 5572 O OG . SER A 1 689 ? 24.831 79.075 -32.375 1.00 14.94 ? 689 SER A OG 1 ATOM 5573 N N . GLU A 1 690 ? 24.713 80.988 -35.127 1.00 15.49 ? 690 GLU A N 1 ATOM 5574 C CA . GLU A 1 690 ? 25.105 82.393 -35.106 1.00 15.89 ? 690 GLU A CA 1 ATOM 5575 C C . GLU A 1 690 ? 25.476 82.900 -33.696 1.00 15.55 ? 690 GLU A C 1 ATOM 5576 O O . GLU A 1 690 ? 26.079 83.974 -33.549 1.00 15.53 ? 690 GLU A O 1 ATOM 5577 C CB . GLU A 1 690 ? 23.977 83.215 -35.753 1.00 17.57 ? 690 GLU A CB 1 ATOM 5578 C CG . GLU A 1 690 ? 22.861 83.644 -34.846 1.00 21.55 ? 690 GLU A CG 1 ATOM 5579 C CD . GLU A 1 690 ? 22.000 84.698 -35.528 1.00 26.84 ? 690 GLU A CD 1 ATOM 5580 O OE1 . GLU A 1 690 ? 21.404 84.374 -36.588 1.00 30.55 ? 690 GLU A OE1 1 ATOM 5581 O OE2 . GLU A 1 690 ? 21.948 85.850 -35.029 1.00 30.77 ? 690 GLU A OE2 1 ATOM 5582 N N . GLN A 1 691 ? 25.144 82.119 -32.657 1.00 15.55 ? 691 GLN A N 1 ATOM 5583 C CA . GLN A 1 691 ? 25.614 82.436 -31.305 1.00 15.21 ? 691 GLN A CA 1 ATOM 5584 C C . GLN A 1 691 ? 26.944 81.761 -30.946 1.00 13.60 ? 691 GLN A C 1 ATOM 5585 O O . GLN A 1 691 ? 27.375 81.861 -29.791 1.00 15.45 ? 691 GLN A O 1 ATOM 5586 C CB . GLN A 1 691 ? 24.588 82.113 -30.218 1.00 16.65 ? 691 GLN A CB 1 ATOM 5587 C CG . GLN A 1 691 ? 23.280 82.864 -30.331 1.00 20.34 ? 691 GLN A CG 1 ATOM 5588 C CD . GLN A 1 691 ? 22.190 81.893 -30.565 1.00 28.87 ? 691 GLN A CD 1 ATOM 5589 O OE1 . GLN A 1 691 ? 21.550 81.442 -29.606 1.00 30.87 ? 691 GLN A OE1 1 ATOM 5590 N NE2 . GLN A 1 691 ? 22.010 81.495 -31.820 1.00 29.04 ? 691 GLN A NE2 1 ATOM 5591 N N . GLY A 1 692 ? 27.589 81.123 -31.906 1.00 12.55 ? 692 GLY A N 1 ATOM 5592 C CA . GLY A 1 692 ? 28.933 80.565 -31.709 1.00 12.82 ? 692 GLY A CA 1 ATOM 5593 C C . GLY A 1 692 ? 28.956 79.220 -31.009 1.00 12.82 ? 692 GLY A C 1 ATOM 5594 O O . GLY A 1 692 ? 30.021 78.813 -30.518 1.00 13.41 ? 692 GLY A O 1 ATOM 5595 N N . LEU A 1 693 ? 27.823 78.514 -31.002 1.00 12.32 ? 693 LEU A N 1 ATOM 5596 C CA . LEU A 1 693 ? 27.703 77.216 -30.316 1.00 12.96 ? 693 LEU A CA 1 ATOM 5597 C C . LEU A 1 693 ? 27.559 76.111 -31.331 1.00 13.06 ? 693 LEU A C 1 ATOM 5598 O O . LEU A 1 693 ? 26.832 76.252 -32.332 1.00 12.95 ? 693 LEU A O 1 ATOM 5599 C CB . LEU A 1 693 ? 26.511 77.247 -29.356 1.00 14.03 ? 693 LEU A CB 1 ATOM 5600 C CG . LEU A 1 693 ? 26.719 78.191 -28.166 1.00 16.76 ? 693 LEU A CG 1 ATOM 5601 C CD1 . LEU A 1 693 ? 25.443 78.942 -27.831 1.00 22.59 ? 693 LEU A CD1 1 ATOM 5602 C CD2 . LEU A 1 693 ? 27.213 77.450 -26.940 1.00 18.61 ? 693 LEU A CD2 1 ATOM 5603 N N . LEU A 1 694 ? 28.253 75.001 -31.099 1.00 11.91 ? 694 LEU A N 1 ATOM 5604 C CA . LEU A 1 694 ? 28.176 73.851 -31.963 1.00 11.94 ? 694 LEU A CA 1 ATOM 5605 C C . LEU A 1 694 ? 26.730 73.448 -32.232 1.00 11.64 ? 694 LEU A C 1 ATOM 5606 O O . LEU A 1 694 ? 25.895 73.463 -31.337 1.00 11.84 ? 694 LEU A O 1 ATOM 5607 C CB . LEU A 1 694 ? 28.924 72.667 -31.306 1.00 12.18 ? 694 LEU A CB 1 ATOM 5608 C CG . LEU A 1 694 ? 29.081 71.396 -32.131 1.00 12.15 ? 694 LEU A CG 1 ATOM 5609 C CD1 . LEU A 1 694 ? 29.985 71.621 -33.300 1.00 13.09 ? 694 LEU A CD1 1 ATOM 5610 C CD2 . LEU A 1 694 ? 29.628 70.276 -31.240 1.00 12.87 ? 694 LEU A CD2 1 ATOM 5611 N N . LYS A 1 695 ? 26.447 73.159 -33.502 1.00 12.80 ? 695 LYS A N 1 ATOM 5612 C CA . LYS A 1 695 ? 25.156 72.595 -33.863 1.00 15.33 ? 695 LYS A CA 1 ATOM 5613 C C . LYS A 1 695 ? 25.255 71.243 -34.552 1.00 14.07 ? 695 LYS A C 1 ATOM 5614 O O . LYS A 1 695 ? 24.275 70.478 -34.493 1.00 15.31 ? 695 LYS A O 1 ATOM 5615 C CB . LYS A 1 695 ? 24.291 73.591 -34.673 1.00 16.39 ? 695 LYS A CB 1 ATOM 5616 C CG . LYS A 1 695 ? 24.908 74.090 -35.941 1.00 19.43 ? 695 LYS A CG 1 ATOM 5617 C CD . LYS A 1 695 ? 23.964 75.105 -36.635 1.00 19.87 ? 695 LYS A CD 1 ATOM 5618 C CE . LYS A 1 695 ? 22.786 74.392 -37.284 1.00 27.24 ? 695 LYS A CE 1 ATOM 5619 N NZ . LYS A 1 695 ? 21.965 75.346 -38.099 1.00 29.30 ? 695 LYS A NZ 1 ATOM 5620 N N . SER A 1 696 ? 26.367 70.912 -35.190 1.00 13.77 ? 696 SER A N 1 ATOM 5621 C CA . SER A 1 696 ? 26.501 69.600 -35.859 1.00 13.98 ? 696 SER A CA 1 ATOM 5622 C C . SER A 1 696 ? 27.946 69.212 -36.091 1.00 14.58 ? 696 SER A C 1 ATOM 5623 O O . SER A 1 696 ? 28.823 70.085 -36.141 1.00 14.33 ? 696 SER A O 1 ATOM 5624 C CB . SER A 1 696 ? 25.706 69.576 -37.189 1.00 15.96 ? 696 SER A CB 1 ATOM 5625 O OG . SER A 1 696 ? 26.392 70.300 -38.194 1.00 18.87 ? 696 SER A OG 1 ATOM 5626 N N . ILE A 1 697 ? 28.211 67.899 -36.227 1.00 14.86 ? 697 ILE A N 1 ATOM 5627 C CA . ILE A 1 697 ? 29.513 67.347 -36.555 1.00 15.01 ? 697 ILE A CA 1 ATOM 5628 C C . ILE A 1 697 ? 29.392 66.403 -37.746 1.00 16.62 ? 697 ILE A C 1 ATOM 5629 O O . ILE A 1 697 ? 28.524 65.522 -37.745 1.00 17.12 ? 697 ILE A O 1 ATOM 5630 C CB . ILE A 1 697 ? 30.135 66.547 -35.338 1.00 15.63 ? 697 ILE A CB 1 ATOM 5631 C CG1 . ILE A 1 697 ? 30.244 67.455 -34.109 1.00 14.09 ? 697 ILE A CG1 1 ATOM 5632 C CG2 . ILE A 1 697 ? 31.494 65.904 -35.705 1.00 15.54 ? 697 ILE A CG2 1 ATOM 5633 C CD1 . ILE A 1 697 ? 30.671 66.714 -32.824 1.00 15.40 ? 697 ILE A CD1 1 ATOM 5634 N N . GLN A 1 698 ? 30.293 66.562 -38.704 1.00 17.17 ? 698 GLN A N 1 ATOM 5635 C CA . GLN A 1 698 ? 30.380 65.673 -39.857 1.00 19.02 ? 698 GLN A CA 1 ATOM 5636 C C . GLN A 1 698 ? 31.735 65.003 -39.833 1.00 19.20 ? 698 GLN A C 1 ATOM 5637 O O . GLN A 1 698 ? 32.754 65.643 -40.013 1.00 17.83 ? 698 GLN A O 1 ATOM 5638 C CB . GLN A 1 698 ? 30.170 66.474 -41.158 1.00 19.49 ? 698 GLN A CB 1 ATOM 5639 C CG . GLN A 1 698 ? 30.040 65.583 -42.397 1.00 21.83 ? 698 GLN A CG 1 ATOM 5640 C CD . GLN A 1 698 ? 30.252 66.362 -43.693 1.00 22.24 ? 698 GLN A CD 1 ATOM 5641 O OE1 . GLN A 1 698 ? 31.143 67.209 -43.784 1.00 25.32 ? 698 GLN A OE1 1 ATOM 5642 N NE2 . GLN A 1 698 ? 29.433 66.070 -44.694 1.00 26.46 ? 698 GLN A NE2 1 ATOM 5643 N N . LEU A 1 699 ? 31.754 63.691 -39.602 1.00 20.86 ? 699 LEU A N 1 ATOM 5644 C CA . LEU A 1 699 ? 33.002 62.976 -39.392 1.00 23.62 ? 699 LEU A CA 1 ATOM 5645 C C . LEU A 1 699 ? 33.892 62.929 -40.633 1.00 25.68 ? 699 LEU A C 1 ATOM 5646 O O . LEU A 1 699 ? 35.102 63.122 -40.538 1.00 26.31 ? 699 LEU A O 1 ATOM 5647 C CB . LEU A 1 699 ? 32.738 61.566 -38.815 1.00 23.29 ? 699 LEU A CB 1 ATOM 5648 C CG . LEU A 1 699 ? 31.994 61.554 -37.474 1.00 23.58 ? 699 LEU A CG 1 ATOM 5649 C CD1 . LEU A 1 699 ? 31.644 60.111 -37.051 1.00 23.99 ? 699 LEU A CD1 1 ATOM 5650 C CD2 . LEU A 1 699 ? 32.843 62.262 -36.432 1.00 23.64 ? 699 LEU A CD2 1 ATOM 5651 N N . THR A 1 700 ? 33.279 62.710 -41.797 1.00 28.47 ? 700 THR A N 1 ATOM 5652 C CA . THR A 1 700 ? 34.017 62.552 -43.056 1.00 31.23 ? 700 THR A CA 1 ATOM 5653 C C . THR A 1 700 ? 33.304 63.292 -44.187 1.00 32.45 ? 700 THR A C 1 ATOM 5654 O O . THR A 1 700 ? 32.135 63.624 -44.062 1.00 32.59 ? 700 THR A O 1 ATOM 5655 C CB . THR A 1 700 ? 34.181 61.044 -43.425 1.00 31.00 ? 700 THR A CB 1 ATOM 5656 O OG1 . THR A 1 700 ? 32.889 60.423 -43.518 1.00 32.21 ? 700 THR A OG1 1 ATOM 5657 C CG2 . THR A 1 700 ? 34.875 60.260 -42.307 1.00 31.75 ? 700 THR A CG2 1 ATOM 5658 N N . GLN A 1 701 ? 34.024 63.537 -45.284 1.00 34.93 ? 701 GLN A N 1 ATOM 5659 C CA . GLN A 1 701 ? 33.503 64.243 -46.468 1.00 37.18 ? 701 GLN A CA 1 ATOM 5660 C C . GLN A 1 701 ? 32.084 63.842 -46.899 1.00 37.72 ? 701 GLN A C 1 ATOM 5661 O O . GLN A 1 701 ? 31.226 64.705 -47.127 1.00 38.45 ? 701 GLN A O 1 ATOM 5662 C CB . GLN A 1 701 ? 34.464 64.072 -47.654 1.00 37.73 ? 701 GLN A CB 1 ATOM 5663 C CG . GLN A 1 701 ? 35.663 65.017 -47.648 1.00 39.92 ? 701 GLN A CG 1 ATOM 5664 C CD . GLN A 1 701 ? 35.361 66.383 -48.265 1.00 42.73 ? 701 GLN A CD 1 ATOM 5665 O OE1 . GLN A 1 701 ? 36.070 67.359 -47.999 1.00 43.79 ? 701 GLN A OE1 1 ATOM 5666 N NE2 . GLN A 1 701 ? 34.316 66.454 -49.088 1.00 44.21 ? 701 GLN A NE2 1 ATOM 5667 N N . ASP A 1 702 ? 31.840 62.540 -47.000 1.00 38.24 ? 702 ASP A N 1 ATOM 5668 C CA . ASP A 1 702 ? 30.556 62.030 -47.483 1.00 39.04 ? 702 ASP A CA 1 ATOM 5669 C C . ASP A 1 702 ? 29.482 61.946 -46.394 1.00 38.67 ? 702 ASP A C 1 ATOM 5670 O O . ASP A 1 702 ? 28.281 62.067 -46.681 1.00 39.08 ? 702 ASP A O 1 ATOM 5671 C CB . ASP A 1 702 ? 30.755 60.648 -48.108 1.00 39.63 ? 702 ASP A CB 1 ATOM 5672 C CG . ASP A 1 702 ? 31.195 59.611 -47.089 1.00 41.58 ? 702 ASP A CG 1 ATOM 5673 O OD1 . ASP A 1 702 ? 32.266 59.799 -46.460 1.00 43.82 ? 702 ASP A OD1 1 ATOM 5674 O OD2 . ASP A 1 702 ? 30.530 58.582 -46.847 1.00 43.79 ? 702 ASP A OD2 1 ATOM 5675 N N . SER A 1 703 ? 29.929 61.761 -45.150 1.00 37.51 ? 703 SER A N 1 ATOM 5676 C CA . SER A 1 703 ? 29.054 61.418 -44.030 1.00 35.94 ? 703 SER A CA 1 ATOM 5677 C C . SER A 1 703 ? 28.034 62.502 -43.658 1.00 34.53 ? 703 SER A C 1 ATOM 5678 O O . SER A 1 703 ? 28.156 63.648 -44.094 1.00 35.08 ? 703 SER A O 1 ATOM 5679 C CB . SER A 1 703 ? 29.895 60.992 -42.816 1.00 36.28 ? 703 SER A CB 1 ATOM 5680 O OG . SER A 1 703 ? 30.550 62.096 -42.216 1.00 35.83 ? 703 SER A OG 1 ATOM 5681 N N . PRO A 1 704 ? 27.023 62.137 -42.866 1.00 33.06 ? 704 PRO A N 1 ATOM 5682 C CA . PRO A 1 704 ? 25.973 63.076 -42.451 1.00 31.31 ? 704 PRO A CA 1 ATOM 5683 C C . PRO A 1 704 ? 26.437 64.147 -41.453 1.00 29.87 ? 704 PRO A C 1 ATOM 5684 O O . PRO A 1 704 ? 27.394 63.935 -40.699 1.00 29.53 ? 704 PRO A O 1 ATOM 5685 C CB . PRO A 1 704 ? 24.938 62.173 -41.772 1.00 31.92 ? 704 PRO A CB 1 ATOM 5686 C CG . PRO A 1 704 ? 25.326 60.790 -42.122 1.00 31.96 ? 704 PRO A CG 1 ATOM 5687 C CD . PRO A 1 704 ? 26.802 60.788 -42.314 1.00 32.93 ? 704 PRO A CD 1 ATOM 5688 N N . HIS A 1 705 ? 25.756 65.291 -41.469 1.00 27.87 ? 705 HIS A N 1 ATOM 5689 C CA . HIS A 1 705 ? 25.937 66.324 -40.442 1.00 26.07 ? 705 HIS A CA 1 ATOM 5690 C C . HIS A 1 705 ? 25.081 65.950 -39.234 1.00 24.42 ? 705 HIS A C 1 ATOM 5691 O O . HIS A 1 705 ? 23.889 66.216 -39.191 1.00 24.23 ? 705 HIS A O 1 ATOM 5692 C CB . HIS A 1 705 ? 25.575 67.712 -41.004 1.00 26.75 ? 705 HIS A CB 1 ATOM 5693 C CG . HIS A 1 705 ? 26.464 68.148 -42.130 1.00 27.93 ? 705 HIS A CG 1 ATOM 5694 N ND1 . HIS A 1 705 ? 27.598 68.908 -41.935 1.00 28.00 ? 705 HIS A ND1 1 ATOM 5695 C CD2 . HIS A 1 705 ? 26.400 67.905 -43.462 1.00 29.87 ? 705 HIS A CD2 1 ATOM 5696 C CE1 . HIS A 1 705 ? 28.194 69.115 -43.097 1.00 30.54 ? 705 HIS A CE1 1 ATOM 5697 N NE2 . HIS A 1 705 ? 27.485 68.519 -44.041 1.00 30.98 ? 705 HIS A NE2 1 ATOM 5698 N N . VAL A 1 706 ? 25.718 65.339 -38.229 1.00 21.46 ? 706 VAL A N 1 ATOM 5699 C CA . VAL A 1 706 ? 25.005 64.825 -37.058 1.00 19.68 ? 706 VAL A CA 1 ATOM 5700 C C . VAL A 1 706 ? 24.662 65.929 -36.054 1.00 18.41 ? 706 VAL A C 1 ATOM 5701 O O . VAL A 1 706 ? 25.581 66.625 -35.589 1.00 16.97 ? 706 VAL A O 1 ATOM 5702 C CB . VAL A 1 706 ? 25.888 63.749 -36.342 1.00 19.24 ? 706 VAL A CB 1 ATOM 5703 C CG1 . VAL A 1 706 ? 25.167 63.169 -35.130 1.00 19.36 ? 706 VAL A CG1 1 ATOM 5704 C CG2 . VAL A 1 706 ? 26.328 62.652 -37.321 1.00 19.91 ? 706 VAL A CG2 1 ATOM 5705 N N . PRO A 1 707 ? 23.396 66.116 -35.685 1.00 17.39 ? 707 PRO A N 1 ATOM 5706 C CA . PRO A 1 707 ? 23.044 67.133 -34.688 1.00 17.44 ? 707 PRO A CA 1 ATOM 5707 C C . PRO A 1 707 ? 23.696 66.882 -33.330 1.00 16.66 ? 707 PRO A C 1 ATOM 5708 O O . PRO A 1 707 ? 23.550 65.823 -32.710 1.00 17.24 ? 707 PRO A O 1 ATOM 5709 C CB . PRO A 1 707 ? 21.513 67.043 -34.593 1.00 17.47 ? 707 PRO A CB 1 ATOM 5710 C CG . PRO A 1 707 ? 21.098 66.344 -35.843 1.00 20.18 ? 707 PRO A CG 1 ATOM 5711 C CD . PRO A 1 707 ? 22.191 65.417 -36.203 1.00 18.43 ? 707 PRO A CD 1 ATOM 5712 N N . VAL A 1 708 ? 24.483 67.863 -32.925 1.00 15.18 ? 708 VAL A N 1 ATOM 5713 C CA . VAL A 1 708 ? 25.143 67.875 -31.632 1.00 14.02 ? 708 VAL A CA 1 ATOM 5714 C C . VAL A 1 708 ? 25.146 69.333 -31.221 1.00 13.07 ? 708 VAL A C 1 ATOM 5715 O O . VAL A 1 708 ? 25.896 70.137 -31.762 1.00 14.63 ? 708 VAL A O 1 ATOM 5716 C CB . VAL A 1 708 ? 26.599 67.383 -31.721 1.00 13.99 ? 708 VAL A CB 1 ATOM 5717 C CG1 . VAL A 1 708 ? 27.237 67.407 -30.342 1.00 14.17 ? 708 VAL A CG1 1 ATOM 5718 C CG2 . VAL A 1 708 ? 26.659 65.983 -32.287 1.00 15.95 ? 708 VAL A CG2 1 ATOM 5719 N N A HIS A 1 709 ? 24.251 69.685 -30.309 0.50 12.65 ? 709 HIS A N 1 ATOM 5720 N N B HIS A 1 709 ? 24.240 69.698 -30.338 0.50 12.47 ? 709 HIS A N 1 ATOM 5721 C CA A HIS A 1 709 ? 23.980 71.088 -29.978 0.50 13.45 ? 709 HIS A CA 1 ATOM 5722 C CA B HIS A 1 709 ? 24.061 71.106 -30.017 0.50 13.10 ? 709 HIS A CA 1 ATOM 5723 C C A HIS A 1 709 ? 24.386 71.463 -28.542 0.50 13.10 ? 709 HIS A C 1 ATOM 5724 C C B HIS A 1 709 ? 24.499 71.374 -28.585 0.50 13.00 ? 709 HIS A C 1 ATOM 5725 O O A HIS A 1 709 ? 23.826 70.928 -27.569 0.50 12.75 ? 709 HIS A O 1 ATOM 5726 O O B HIS A 1 709 ? 24.099 70.662 -27.673 0.50 12.74 ? 709 HIS A O 1 ATOM 5727 C CB A HIS A 1 709 ? 22.490 71.397 -30.177 0.50 14.12 ? 709 HIS A CB 1 ATOM 5728 C CB B HIS A 1 709 ? 22.601 71.512 -30.225 0.50 13.57 ? 709 HIS A CB 1 ATOM 5729 C CG A HIS A 1 709 ? 22.046 71.369 -31.607 0.50 16.24 ? 709 HIS A CG 1 ATOM 5730 C CG B HIS A 1 709 ? 22.314 72.957 -29.937 0.50 15.23 ? 709 HIS A CG 1 ATOM 5731 N ND1 A HIS A 1 709 ? 21.632 72.498 -32.281 0.50 21.38 ? 709 HIS A ND1 1 ATOM 5732 N ND1 B HIS A 1 709 ? 23.104 73.988 -30.407 0.50 17.48 ? 709 HIS A ND1 1 ATOM 5733 C CD2 A HIS A 1 709 ? 21.964 70.348 -32.492 0.50 18.30 ? 709 HIS A CD2 1 ATOM 5734 C CD2 B HIS A 1 709 ? 21.283 73.540 -29.282 0.50 17.20 ? 709 HIS A CD2 1 ATOM 5735 C CE1 A HIS A 1 709 ? 21.299 72.168 -33.517 0.50 20.02 ? 709 HIS A CE1 1 ATOM 5736 C CE1 B HIS A 1 709 ? 22.591 75.143 -30.016 0.50 17.82 ? 709 HIS A CE1 1 ATOM 5737 N NE2 A HIS A 1 709 ? 21.509 70.873 -33.675 0.50 16.55 ? 709 HIS A NE2 1 ATOM 5738 N NE2 B HIS A 1 709 ? 21.486 74.899 -29.334 0.50 18.48 ? 709 HIS A NE2 1 ATOM 5739 N N . PHE A 1 710 ? 25.344 72.391 -28.409 1.00 12.57 ? 710 PHE A N 1 ATOM 5740 C CA . PHE A 1 710 ? 25.706 72.885 -27.082 1.00 12.21 ? 710 PHE A CA 1 ATOM 5741 C C . PHE A 1 710 ? 24.717 73.967 -26.643 1.00 12.59 ? 710 PHE A C 1 ATOM 5742 O O . PHE A 1 710 ? 24.311 74.834 -27.465 1.00 12.70 ? 710 PHE A O 1 ATOM 5743 C CB . PHE A 1 710 ? 27.133 73.469 -27.036 1.00 12.84 ? 710 PHE A CB 1 ATOM 5744 C CG . PHE A 1 710 ? 28.218 72.480 -26.629 1.00 13.08 ? 710 PHE A CG 1 ATOM 5745 C CD1 . PHE A 1 710 ? 28.167 71.839 -25.396 1.00 15.63 ? 710 PHE A CD1 1 ATOM 5746 C CD2 . PHE A 1 710 ? 29.330 72.267 -27.433 1.00 16.29 ? 710 PHE A CD2 1 ATOM 5747 C CE1 . PHE A 1 710 ? 29.185 70.943 -25.006 1.00 16.97 ? 710 PHE A CE1 1 ATOM 5748 C CE2 . PHE A 1 710 ? 30.361 71.379 -27.019 1.00 15.04 ? 710 PHE A CE2 1 ATOM 5749 C CZ . PHE A 1 710 ? 30.268 70.731 -25.823 1.00 15.79 ? 710 PHE A CZ 1 ATOM 5750 N N . LYS A 1 711 ? 24.335 73.957 -25.379 1.00 11.62 ? 711 LYS A N 1 ATOM 5751 C CA . LYS A 1 711 ? 23.416 74.922 -24.811 1.00 14.34 ? 711 LYS A CA 1 ATOM 5752 C C . LYS A 1 711 ? 23.834 75.147 -23.371 1.00 13.40 ? 711 LYS A C 1 ATOM 5753 O O . LYS A 1 711 ? 24.253 74.171 -22.698 1.00 14.32 ? 711 LYS A O 1 ATOM 5754 C CB . LYS A 1 711 ? 21.989 74.347 -24.848 1.00 15.50 ? 711 LYS A CB 1 ATOM 5755 C CG . LYS A 1 711 ? 20.903 75.281 -24.339 1.00 18.52 ? 711 LYS A CG 1 ATOM 5756 C CD . LYS A 1 711 ? 19.501 74.640 -24.491 1.00 20.16 ? 711 LYS A CD 1 ATOM 5757 C CE . LYS A 1 711 ? 19.048 74.635 -25.957 1.00 23.41 ? 711 LYS A CE 1 ATOM 5758 N NZ . LYS A 1 711 ? 17.753 73.891 -26.125 1.00 25.24 ? 711 LYS A NZ 1 ATOM 5759 N N . PHE A 1 712 ? 23.735 76.375 -22.876 1.00 11.03 ? 712 PHE A N 1 ATOM 5760 C CA . PHE A 1 712 ? 23.917 76.712 -21.480 1.00 11.48 ? 712 PHE A CA 1 ATOM 5761 C C . PHE A 1 712 ? 22.604 77.017 -20.803 1.00 10.80 ? 712 PHE A C 1 ATOM 5762 O O . PHE A 1 712 ? 21.768 77.749 -21.360 1.00 11.78 ? 712 PHE A O 1 ATOM 5763 C CB . PHE A 1 712 ? 24.934 77.863 -21.292 1.00 11.87 ? 712 PHE A CB 1 ATOM 5764 C CG . PHE A 1 712 ? 26.349 77.450 -21.603 1.00 11.19 ? 712 PHE A CG 1 ATOM 5765 C CD1 . PHE A 1 712 ? 26.822 77.485 -22.911 1.00 12.05 ? 712 PHE A CD1 1 ATOM 5766 C CD2 . PHE A 1 712 ? 27.185 76.965 -20.598 1.00 11.30 ? 712 PHE A CD2 1 ATOM 5767 C CE1 . PHE A 1 712 ? 28.127 77.084 -23.232 1.00 10.75 ? 712 PHE A CE1 1 ATOM 5768 C CE2 . PHE A 1 712 ? 28.468 76.564 -20.901 1.00 11.06 ? 712 PHE A CE2 1 ATOM 5769 C CZ . PHE A 1 712 ? 28.944 76.602 -22.197 1.00 11.14 ? 712 PHE A CZ 1 ATOM 5770 N N . LEU A 1 713 ? 22.382 76.438 -19.637 1.00 10.08 ? 713 LEU A N 1 ATOM 5771 C CA . LEU A 1 713 ? 21.160 76.654 -18.864 1.00 10.48 ? 713 LEU A CA 1 ATOM 5772 C C . LEU A 1 713 ? 21.470 76.951 -17.411 1.00 10.56 ? 713 LEU A C 1 ATOM 5773 O O . LEU A 1 713 ? 22.667 76.838 -16.973 1.00 10.68 ? 713 LEU A O 1 ATOM 5774 C CB . LEU A 1 713 ? 20.231 75.432 -18.970 1.00 10.71 ? 713 LEU A CB 1 ATOM 5775 C CG . LEU A 1 713 ? 19.889 74.989 -20.380 1.00 11.31 ? 713 LEU A CG 1 ATOM 5776 C CD1 . LEU A 1 713 ? 20.765 73.823 -20.836 1.00 13.88 ? 713 LEU A CD1 1 ATOM 5777 C CD2 . LEU A 1 713 ? 18.401 74.530 -20.495 1.00 13.27 ? 713 LEU A CD2 1 ATOM 5778 N N . LYS A 1 714 ? 20.466 77.305 -16.633 1.00 11.55 ? 714 LYS A N 1 ATOM 5779 C CA . LYS A 1 714 ? 20.653 77.591 -15.236 1.00 13.32 ? 714 LYS A CA 1 ATOM 5780 C C . LYS A 1 714 ? 19.627 76.906 -14.385 1.00 13.11 ? 714 LYS A C 1 ATOM 5781 O O . LYS A 1 714 ? 18.424 76.866 -14.709 1.00 14.20 ? 714 LYS A O 1 ATOM 5782 C CB . LYS A 1 714 ? 20.637 79.093 -14.941 1.00 16.34 ? 714 LYS A CB 1 ATOM 5783 C CG . LYS A 1 714 ? 19.561 79.861 -15.632 1.00 21.28 ? 714 LYS A CG 1 ATOM 5784 C CD . LYS A 1 714 ? 19.618 81.348 -15.248 1.00 26.87 ? 714 LYS A CD 1 ATOM 5785 C CE . LYS A 1 714 ? 20.968 81.992 -15.532 1.00 30.16 ? 714 LYS A CE 1 ATOM 5786 N NZ . LYS A 1 714 ? 20.957 83.460 -15.211 1.00 33.96 ? 714 LYS A NZ 1 ATOM 5787 N N . TYR A 1 715 ? 20.089 76.362 -13.265 1.00 10.92 ? 715 TYR A N 1 ATOM 5788 C CA . TYR A 1 715 ? 19.221 75.886 -12.219 1.00 10.76 ? 715 TYR A CA 1 ATOM 5789 C C . TYR A 1 715 ? 19.177 76.934 -11.122 1.00 12.13 ? 715 TYR A C 1 ATOM 5790 O O . TYR A 1 715 ? 20.150 77.675 -10.874 1.00 12.25 ? 715 TYR A O 1 ATOM 5791 C CB . TYR A 1 715 ? 19.784 74.599 -11.591 1.00 11.10 ? 715 TYR A CB 1 ATOM 5792 C CG . TYR A 1 715 ? 19.721 73.387 -12.446 1.00 9.55 ? 715 TYR A CG 1 ATOM 5793 C CD1 . TYR A 1 715 ? 18.548 72.641 -12.510 1.00 10.86 ? 715 TYR A CD1 1 ATOM 5794 C CD2 . TYR A 1 715 ? 20.829 72.950 -13.191 1.00 11.20 ? 715 TYR A CD2 1 ATOM 5795 C CE1 . TYR A 1 715 ? 18.465 71.500 -13.280 1.00 10.35 ? 715 TYR A CE1 1 ATOM 5796 C CE2 . TYR A 1 715 ? 20.758 71.803 -13.987 1.00 9.58 ? 715 TYR A CE2 1 ATOM 5797 C CZ . TYR A 1 715 ? 19.565 71.058 -14.029 1.00 9.13 ? 715 TYR A CZ 1 ATOM 5798 O OH . TYR A 1 715 ? 19.467 69.922 -14.781 1.00 10.60 ? 715 TYR A OH 1 ATOM 5799 N N . GLY A 1 716 ? 18.058 76.995 -10.411 1.00 12.23 ? 716 GLY A N 1 ATOM 5800 C CA . GLY A 1 716 ? 17.893 77.911 -9.311 1.00 12.31 ? 716 GLY A CA 1 ATOM 5801 C C . GLY A 1 716 ? 17.759 77.130 -8.012 1.00 12.99 ? 716 GLY A C 1 ATOM 5802 O O . GLY A 1 716 ? 18.100 75.907 -7.953 1.00 13.53 ? 716 GLY A O 1 ATOM 5803 N N . VAL A 1 717 ? 17.289 77.802 -6.972 1.00 13.39 ? 717 VAL A N 1 ATOM 5804 C CA . VAL A 1 717 ? 17.174 77.254 -5.631 1.00 14.80 ? 717 VAL A CA 1 ATOM 5805 C C . VAL A 1 717 ? 15.705 77.411 -5.197 1.00 15.44 ? 717 VAL A C 1 ATOM 5806 O O . VAL A 1 717 ? 15.020 78.339 -5.647 1.00 16.64 ? 717 VAL A O 1 ATOM 5807 C CB . VAL A 1 717 ? 18.128 78.000 -4.663 1.00 15.07 ? 717 VAL A CB 1 ATOM 5808 C CG1 . VAL A 1 717 ? 17.893 77.650 -3.198 1.00 18.40 ? 717 VAL A CG1 1 ATOM 5809 C CG2 . VAL A 1 717 ? 19.584 77.736 -5.055 1.00 14.94 ? 717 VAL A CG2 1 ATOM 5810 N N . ARG A 1 718 ? 15.230 76.520 -4.337 1.00 15.01 ? 718 ARG A N 1 ATOM 5811 C CA . ARG A 1 718 ? 13.844 76.562 -3.846 1.00 16.52 ? 718 ARG A CA 1 ATOM 5812 C C . ARG A 1 718 ? 13.616 77.731 -2.922 1.00 18.66 ? 718 ARG A C 1 ATOM 5813 O O . ARG A 1 718 ? 14.461 78.068 -2.114 1.00 19.48 ? 718 ARG A O 1 ATOM 5814 C CB . ARG A 1 718 ? 13.503 75.252 -3.129 1.00 15.71 ? 718 ARG A CB 1 ATOM 5815 C CG . ARG A 1 718 ? 13.587 74.098 -4.082 1.00 16.25 ? 718 ARG A CG 1 ATOM 5816 C CD . ARG A 1 718 ? 13.549 72.738 -3.412 1.00 16.72 ? 718 ARG A CD 1 ATOM 5817 N NE . ARG A 1 718 ? 13.821 71.718 -4.409 1.00 15.71 ? 718 ARG A NE 1 ATOM 5818 C CZ . ARG A 1 718 ? 13.799 70.405 -4.174 1.00 16.63 ? 718 ARG A CZ 1 ATOM 5819 N NH1 . ARG A 1 718 ? 13.484 69.953 -2.963 1.00 15.24 ? 718 ARG A NH1 1 ATOM 5820 N NH2 . ARG A 1 718 ? 14.089 69.571 -5.160 1.00 16.82 ? 718 ARG A NH2 1 ATOM 5821 N N . SER A 1 719 ? 12.445 78.348 -3.058 1.00 20.30 ? 719 SER A N 1 ATOM 5822 C CA . SER A 1 719 ? 12.062 79.458 -2.200 1.00 22.45 ? 719 SER A CA 1 ATOM 5823 C C . SER A 1 719 ? 11.306 78.949 -0.965 1.00 23.22 ? 719 SER A C 1 ATOM 5824 O O . SER A 1 719 ? 11.041 79.715 -0.048 1.00 24.68 ? 719 SER A O 1 ATOM 5825 C CB . SER A 1 719 ? 11.196 80.445 -2.995 1.00 22.33 ? 719 SER A CB 1 ATOM 5826 O OG . SER A 1 719 ? 10.010 79.821 -3.412 1.00 25.41 ? 719 SER A OG 1 ATOM 5827 N N . HIS A 1 720 ? 10.920 77.672 -0.967 1.00 23.95 ? 720 HIS A N 1 ATOM 5828 C CA . HIS A 1 720 ? 10.334 77.015 0.196 1.00 24.38 ? 720 HIS A CA 1 ATOM 5829 C C . HIS A 1 720 ? 11.002 75.660 0.376 1.00 23.52 ? 720 HIS A C 1 ATOM 5830 O O . HIS A 1 720 ? 11.357 75.016 -0.608 1.00 23.87 ? 720 HIS A O 1 ATOM 5831 C CB . HIS A 1 720 ? 8.833 76.787 -0.005 1.00 25.75 ? 720 HIS A CB 1 ATOM 5832 C CG . HIS A 1 720 ? 8.099 78.004 -0.460 1.00 27.94 ? 720 HIS A CG 1 ATOM 5833 N ND1 . HIS A 1 720 ? 7.791 79.046 0.389 1.00 32.59 ? 720 HIS A ND1 1 ATOM 5834 C CD2 . HIS A 1 720 ? 7.631 78.356 -1.681 1.00 30.78 ? 720 HIS A CD2 1 ATOM 5835 C CE1 . HIS A 1 720 ? 7.149 79.981 -0.289 1.00 31.85 ? 720 HIS A CE1 1 ATOM 5836 N NE2 . HIS A 1 720 ? 7.044 79.590 -1.547 1.00 31.13 ? 720 HIS A NE2 1 ATOM 5837 N N . GLY A 1 721 ? 11.127 75.229 1.624 1.00 22.74 ? 721 GLY A N 1 ATOM 5838 C CA . GLY A 1 721 ? 11.721 73.939 1.933 1.00 22.03 ? 721 GLY A CA 1 ATOM 5839 C C . GLY A 1 721 ? 13.236 74.025 1.918 1.00 21.23 ? 721 GLY A C 1 ATOM 5840 O O . GLY A 1 721 ? 13.822 75.071 2.239 1.00 21.77 ? 721 GLY A O 1 ATOM 5841 N N . ASP A 1 722 ? 13.877 72.930 1.528 1.00 19.37 ? 722 ASP A N 1 ATOM 5842 C CA . ASP A 1 722 ? 15.322 72.822 1.743 1.00 17.42 ? 722 ASP A CA 1 ATOM 5843 C C . ASP A 1 722 ? 16.100 73.518 0.647 1.00 16.49 ? 722 ASP A C 1 ATOM 5844 O O . ASP A 1 722 ? 15.759 73.428 -0.511 1.00 16.05 ? 722 ASP A O 1 ATOM 5845 C CB . ASP A 1 722 ? 15.762 71.359 1.843 1.00 17.05 ? 722 ASP A CB 1 ATOM 5846 C CG . ASP A 1 722 ? 15.183 70.634 3.057 1.00 18.03 ? 722 ASP A CG 1 ATOM 5847 O OD1 . ASP A 1 722 ? 14.959 71.238 4.148 1.00 19.04 ? 722 ASP A OD1 1 ATOM 5848 O OD2 . ASP A 1 722 ? 14.940 69.412 2.986 1.00 18.47 ? 722 ASP A OD2 1 ATOM 5849 N N . ARG A 1 723 ? 17.177 74.195 1.049 1.00 15.43 ? 723 ARG A N 1 ATOM 5850 C CA . ARG A 1 723 ? 17.992 74.972 0.124 1.00 15.31 ? 723 ARG A CA 1 ATOM 5851 C C . ARG A 1 723 ? 19.271 74.216 -0.292 1.00 13.44 ? 723 ARG A C 1 ATOM 5852 O O . ARG A 1 723 ? 19.924 73.572 0.543 1.00 13.06 ? 723 ARG A O 1 ATOM 5853 C CB . ARG A 1 723 ? 18.391 76.295 0.790 1.00 17.22 ? 723 ARG A CB 1 ATOM 5854 C CG . ARG A 1 723 ? 17.358 77.475 0.775 1.00 21.97 ? 723 ARG A CG 1 ATOM 5855 C CD . ARG A 1 723 ? 15.866 77.153 0.838 1.00 28.66 ? 723 ARG A CD 1 ATOM 5856 N NE . ARG A 1 723 ? 15.081 78.391 0.977 1.00 29.64 ? 723 ARG A NE 1 ATOM 5857 C CZ . ARG A 1 723 ? 14.117 78.596 1.877 1.00 34.23 ? 723 ARG A CZ 1 ATOM 5858 N NH1 . ARG A 1 723 ? 13.753 77.640 2.726 1.00 35.68 ? 723 ARG A NH1 1 ATOM 5859 N NH2 . ARG A 1 723 ? 13.489 79.765 1.915 1.00 35.84 ? 723 ARG A NH2 1 ATOM 5860 N N . SER A 1 724 ? 19.617 74.321 -1.576 1.00 12.21 ? 724 SER A N 1 ATOM 5861 C CA . SER A 1 724 ? 20.922 73.863 -2.069 1.00 11.70 ? 724 SER A CA 1 ATOM 5862 C C . SER A 1 724 ? 22.025 74.566 -1.305 1.00 11.52 ? 724 SER A C 1 ATOM 5863 O O . SER A 1 724 ? 21.918 75.750 -0.974 1.00 13.19 ? 724 SER A O 1 ATOM 5864 C CB . SER A 1 724 ? 21.078 74.194 -3.539 1.00 11.48 ? 724 SER A CB 1 ATOM 5865 O OG . SER A 1 724 ? 20.018 73.576 -4.249 1.00 11.58 ? 724 SER A OG 1 ATOM 5866 N N . GLY A 1 725 ? 23.143 73.855 -1.123 1.00 10.75 ? 725 GLY A N 1 ATOM 5867 C CA . GLY A 1 725 ? 24.347 74.431 -0.522 1.00 9.78 ? 725 GLY A CA 1 ATOM 5868 C C . GLY A 1 725 ? 25.551 73.678 -1.062 1.00 9.07 ? 725 GLY A C 1 ATOM 5869 O O . GLY A 1 725 ? 25.476 73.040 -2.111 1.00 9.52 ? 725 GLY A O 1 ATOM 5870 N N . ALA A 1 726 ? 26.671 73.755 -0.350 1.00 8.49 ? 726 ALA A N 1 ATOM 5871 C CA . ALA A 1 726 ? 27.911 73.109 -0.818 1.00 8.40 ? 726 ALA A CA 1 ATOM 5872 C C . ALA A 1 726 ? 27.761 71.606 -1.060 1.00 8.07 ? 726 ALA A C 1 ATOM 5873 O O . ALA A 1 726 ? 28.437 71.061 -1.935 1.00 8.15 ? 726 ALA A O 1 ATOM 5874 C CB . ALA A 1 726 ? 29.063 73.345 0.126 1.00 9.82 ? 726 ALA A CB 1 ATOM 5875 N N . TYR A 1 727 ? 26.920 70.939 -0.270 1.00 7.99 ? 727 TYR A N 1 ATOM 5876 C CA . TYR A 1 727 ? 26.758 69.481 -0.367 1.00 7.66 ? 727 TYR A CA 1 ATOM 5877 C C . TYR A 1 727 ? 25.580 69.097 -1.268 1.00 7.58 ? 727 TYR A C 1 ATOM 5878 O O . TYR A 1 727 ? 25.692 68.232 -2.133 1.00 8.08 ? 727 TYR A O 1 ATOM 5879 C CB . TYR A 1 727 ? 26.500 68.878 1.008 1.00 8.20 ? 727 TYR A CB 1 ATOM 5880 C CG . TYR A 1 727 ? 27.557 69.158 2.057 1.00 8.51 ? 727 TYR A CG 1 ATOM 5881 C CD1 . TYR A 1 727 ? 27.526 70.329 2.800 1.00 8.62 ? 727 TYR A CD1 1 ATOM 5882 C CD2 . TYR A 1 727 ? 28.569 68.224 2.340 1.00 8.76 ? 727 TYR A CD2 1 ATOM 5883 C CE1 . TYR A 1 727 ? 28.466 70.562 3.797 1.00 8.32 ? 727 TYR A CE1 1 ATOM 5884 C CE2 . TYR A 1 727 ? 29.507 68.452 3.337 1.00 8.42 ? 727 TYR A CE2 1 ATOM 5885 C CZ . TYR A 1 727 ? 29.453 69.615 4.059 1.00 7.52 ? 727 TYR A CZ 1 ATOM 5886 O OH . TYR A 1 727 ? 30.351 69.837 5.088 1.00 8.95 ? 727 TYR A OH 1 ATOM 5887 N N . LEU A 1 728 ? 24.420 69.716 -0.985 1.00 8.95 ? 728 LEU A N 1 ATOM 5888 C CA . LEU A 1 728 ? 23.133 69.313 -1.590 1.00 9.05 ? 728 LEU A CA 1 ATOM 5889 C C . LEU A 1 728 ? 22.787 70.065 -2.855 1.00 9.07 ? 728 LEU A C 1 ATOM 5890 O O . LEU A 1 728 ? 22.978 71.289 -2.936 1.00 9.82 ? 728 LEU A O 1 ATOM 5891 C CB . LEU A 1 728 ? 21.984 69.575 -0.606 1.00 10.43 ? 728 LEU A CB 1 ATOM 5892 C CG . LEU A 1 728 ? 22.130 68.937 0.772 1.00 9.18 ? 728 LEU A CG 1 ATOM 5893 C CD1 . LEU A 1 728 ? 20.817 69.191 1.585 1.00 10.52 ? 728 LEU A CD1 1 ATOM 5894 C CD2 . LEU A 1 728 ? 22.455 67.443 0.702 1.00 11.17 ? 728 LEU A CD2 1 ATOM 5895 N N . PHE A 1 729 ? 22.229 69.355 -3.832 1.00 9.46 ? 729 PHE A N 1 ATOM 5896 C CA . PHE A 1 729 ? 21.661 69.945 -5.030 1.00 9.97 ? 729 PHE A CA 1 ATOM 5897 C C . PHE A 1 729 ? 20.148 69.751 -4.936 1.00 10.36 ? 729 PHE A C 1 ATOM 5898 O O . PHE A 1 729 ? 19.661 68.632 -5.021 1.00 9.94 ? 729 PHE A O 1 ATOM 5899 C CB . PHE A 1 729 ? 22.236 69.229 -6.234 1.00 9.82 ? 729 PHE A CB 1 ATOM 5900 C CG . PHE A 1 729 ? 21.721 69.713 -7.586 1.00 8.94 ? 729 PHE A CG 1 ATOM 5901 C CD1 . PHE A 1 729 ? 21.406 71.060 -7.839 1.00 10.02 ? 729 PHE A CD1 1 ATOM 5902 C CD2 . PHE A 1 729 ? 21.638 68.793 -8.626 1.00 8.91 ? 729 PHE A CD2 1 ATOM 5903 C CE1 . PHE A 1 729 ? 20.988 71.444 -9.118 1.00 9.56 ? 729 PHE A CE1 1 ATOM 5904 C CE2 . PHE A 1 729 ? 21.214 69.173 -9.894 1.00 8.66 ? 729 PHE A CE2 1 ATOM 5905 C CZ . PHE A 1 729 ? 20.893 70.502 -10.129 1.00 9.85 ? 729 PHE A CZ 1 ATOM 5906 N N . LEU A 1 730 ? 19.447 70.870 -4.748 1.00 9.98 ? 730 LEU A N 1 ATOM 5907 C CA . LEU A 1 730 ? 17.986 70.838 -4.572 1.00 11.19 ? 730 LEU A CA 1 ATOM 5908 C C . LEU A 1 730 ? 17.363 71.846 -5.544 1.00 10.72 ? 730 LEU A C 1 ATOM 5909 O O . LEU A 1 730 ? 16.934 72.935 -5.113 1.00 11.49 ? 730 LEU A O 1 ATOM 5910 C CB . LEU A 1 730 ? 17.651 71.171 -3.123 1.00 11.29 ? 730 LEU A CB 1 ATOM 5911 C CG . LEU A 1 730 ? 18.016 70.085 -2.107 1.00 11.26 ? 730 LEU A CG 1 ATOM 5912 C CD1 . LEU A 1 730 ? 17.988 70.602 -0.711 1.00 13.38 ? 730 LEU A CD1 1 ATOM 5913 C CD2 . LEU A 1 730 ? 17.050 68.892 -2.286 1.00 14.56 ? 730 LEU A CD2 1 ATOM 5914 N N . PRO A 1 731 ? 17.378 71.532 -6.831 1.00 10.57 ? 731 PRO A N 1 ATOM 5915 C CA . PRO A 1 731 ? 16.930 72.504 -7.845 1.00 11.97 ? 731 PRO A CA 1 ATOM 5916 C C . PRO A 1 731 ? 15.440 72.804 -7.711 1.00 12.61 ? 731 PRO A C 1 ATOM 5917 O O . PRO A 1 731 ? 14.647 71.965 -7.254 1.00 13.28 ? 731 PRO A O 1 ATOM 5918 C CB . PRO A 1 731 ? 17.193 71.783 -9.166 1.00 12.02 ? 731 PRO A CB 1 ATOM 5919 C CG . PRO A 1 731 ? 17.187 70.302 -8.829 1.00 12.45 ? 731 PRO A CG 1 ATOM 5920 C CD . PRO A 1 731 ? 17.771 70.254 -7.448 1.00 10.88 ? 731 PRO A CD 1 ATOM 5921 N N . ASN A 1 732 ? 15.073 74.012 -8.136 1.00 13.67 ? 732 ASN A N 1 ATOM 5922 C CA . ASN A 1 732 ? 13.652 74.403 -8.194 1.00 15.56 ? 732 ASN A CA 1 ATOM 5923 C C . ASN A 1 732 ? 13.140 74.073 -9.587 1.00 15.29 ? 732 ASN A C 1 ATOM 5924 O O . ASN A 1 732 ? 12.663 74.967 -10.324 1.00 18.04 ? 732 ASN A O 1 ATOM 5925 C CB . ASN A 1 732 ? 13.471 75.900 -7.888 1.00 16.76 ? 732 ASN A CB 1 ATOM 5926 C CG . ASN A 1 732 ? 14.180 76.794 -8.884 1.00 19.83 ? 732 ASN A CG 1 ATOM 5927 O OD1 . ASN A 1 732 ? 15.171 76.408 -9.492 1.00 21.12 ? 732 ASN A OD1 1 ATOM 5928 N ND2 . ASN A 1 732 ? 13.651 78.010 -9.073 1.00 22.49 ? 732 ASN A ND2 1 ATOM 5929 N N . GLY A 1 733 ? 13.247 72.817 -9.994 1.00 14.24 ? 733 GLY A N 1 ATOM 5930 C CA . GLY A 1 733 ? 12.778 72.373 -11.293 1.00 14.64 ? 733 GLY A CA 1 ATOM 5931 C C . GLY A 1 733 ? 13.881 72.215 -12.336 1.00 13.63 ? 733 GLY A C 1 ATOM 5932 O O . GLY A 1 733 ? 15.039 72.582 -12.058 1.00 13.48 ? 733 GLY A O 1 ATOM 5933 N N . PRO A 1 734 ? 13.550 71.719 -13.516 1.00 12.75 ? 734 PRO A N 1 ATOM 5934 C CA . PRO A 1 734 ? 14.504 71.635 -14.621 1.00 14.05 ? 734 PRO A CA 1 ATOM 5935 C C . PRO A 1 734 ? 15.118 72.994 -14.938 1.00 14.04 ? 734 PRO A C 1 ATOM 5936 O O . PRO A 1 734 ? 14.545 74.053 -14.671 1.00 13.30 ? 734 PRO A O 1 ATOM 5937 C CB . PRO A 1 734 ? 13.648 71.169 -15.804 1.00 15.06 ? 734 PRO A CB 1 ATOM 5938 C CG . PRO A 1 734 ? 12.480 70.494 -15.161 1.00 16.95 ? 734 PRO A CG 1 ATOM 5939 C CD . PRO A 1 734 ? 12.216 71.185 -13.880 1.00 14.08 ? 734 PRO A CD 1 ATOM 5940 N N . ALA A 1 735 ? 16.325 72.941 -15.499 1.00 12.73 ? 735 ALA A N 1 ATOM 5941 C CA . ALA A 1 735 ? 17.056 74.151 -15.855 1.00 13.65 ? 735 ALA A CA 1 ATOM 5942 C C . ALA A 1 735 ? 16.340 74.980 -16.928 1.00 13.47 ? 735 ALA A C 1 ATOM 5943 O O . ALA A 1 735 ? 15.631 74.427 -17.756 1.00 14.71 ? 735 ALA A O 1 ATOM 5944 C CB . ALA A 1 735 ? 18.451 73.770 -16.307 1.00 12.99 ? 735 ALA A CB 1 ATOM 5945 N N . SER A 1 736 ? 16.580 76.292 -16.883 1.00 14.11 ? 736 SER A N 1 ATOM 5946 C CA . SER A 1 736 ? 16.014 77.251 -17.850 1.00 15.92 ? 736 SER A CA 1 ATOM 5947 C C . SER A 1 736 ? 17.155 77.785 -18.714 1.00 16.11 ? 736 SER A C 1 ATOM 5948 O O . SER A 1 736 ? 18.242 78.021 -18.192 1.00 15.27 ? 736 SER A O 1 ATOM 5949 C CB . SER A 1 736 ? 15.367 78.420 -17.113 1.00 17.34 ? 736 SER A CB 1 ATOM 5950 O OG . SER A 1 736 ? 14.504 77.976 -16.087 1.00 23.91 ? 736 SER A OG 1 ATOM 5951 N N . PRO A 1 737 ? 16.954 77.972 -20.022 1.00 17.32 ? 737 PRO A N 1 ATOM 5952 C CA . PRO A 1 737 ? 18.062 78.434 -20.886 1.00 18.44 ? 737 PRO A CA 1 ATOM 5953 C C . PRO A 1 737 ? 18.635 79.785 -20.448 1.00 18.34 ? 737 PRO A C 1 ATOM 5954 O O . PRO A 1 737 ? 17.887 80.667 -20.048 1.00 19.38 ? 737 PRO A O 1 ATOM 5955 C CB . PRO A 1 737 ? 17.424 78.551 -22.279 1.00 19.38 ? 737 PRO A CB 1 ATOM 5956 C CG . PRO A 1 737 ? 16.187 77.686 -22.210 1.00 19.86 ? 737 PRO A CG 1 ATOM 5957 C CD . PRO A 1 737 ? 15.707 77.734 -20.784 1.00 18.57 ? 737 PRO A CD 1 ATOM 5958 N N . VAL A 1 738 ? 19.960 79.938 -20.496 1.00 18.30 ? 738 VAL A N 1 ATOM 5959 C CA . VAL A 1 738 ? 20.570 81.251 -20.238 1.00 18.72 ? 738 VAL A CA 1 ATOM 5960 C C . VAL A 1 738 ? 20.178 82.155 -21.417 1.00 19.01 ? 738 VAL A C 1 ATOM 5961 O O . VAL A 1 738 ? 20.260 81.739 -22.574 1.00 18.60 ? 738 VAL A O 1 ATOM 5962 C CB . VAL A 1 738 ? 22.103 81.140 -20.129 1.00 18.17 ? 738 VAL A CB 1 ATOM 5963 C CG1 . VAL A 1 738 ? 22.786 82.540 -20.105 1.00 19.23 ? 738 VAL A CG1 1 ATOM 5964 C CG2 . VAL A 1 738 ? 22.506 80.293 -18.889 1.00 18.27 ? 738 VAL A CG2 1 ATOM 5965 N N . GLU A 1 739 ? 19.741 83.377 -21.118 1.00 19.86 ? 739 GLU A N 1 ATOM 5966 C CA . GLU A 1 739 ? 19.416 84.331 -22.185 1.00 20.92 ? 739 GLU A CA 1 ATOM 5967 C C . GLU A 1 739 ? 20.721 84.882 -22.735 1.00 19.87 ? 739 GLU A C 1 ATOM 5968 O O . GLU A 1 739 ? 21.499 85.485 -21.999 1.00 20.31 ? 739 GLU A O 1 ATOM 5969 C CB . GLU A 1 739 ? 18.597 85.486 -21.644 1.00 21.59 ? 739 GLU A CB 1 ATOM 5970 C CG . GLU A 1 739 ? 17.170 85.134 -21.301 1.00 27.02 ? 739 GLU A CG 1 ATOM 5971 C CD . GLU A 1 739 ? 16.399 86.362 -20.863 1.00 33.75 ? 739 GLU A CD 1 ATOM 5972 O OE1 . GLU A 1 739 ? 16.367 87.341 -21.640 1.00 36.29 ? 739 GLU A OE1 1 ATOM 5973 O OE2 . GLU A 1 739 ? 15.834 86.350 -19.744 1.00 37.42 ? 739 GLU A OE2 1 ATOM 5974 N N . LEU A 1 740 ? 20.951 84.643 -24.015 1.00 19.86 ? 740 LEU A N 1 ATOM 5975 C CA . LEU A 1 740 ? 22.258 84.924 -24.611 1.00 20.06 ? 740 LEU A CA 1 ATOM 5976 C C . LEU A 1 740 ? 22.416 86.316 -25.210 1.00 20.50 ? 740 LEU A C 1 ATOM 5977 O O . LEU A 1 740 ? 23.532 86.751 -25.417 1.00 20.62 ? 740 LEU A O 1 ATOM 5978 C CB . LEU A 1 740 ? 22.594 83.876 -25.664 1.00 20.33 ? 740 LEU A CB 1 ATOM 5979 C CG . LEU A 1 740 ? 22.557 82.418 -25.209 1.00 19.69 ? 740 LEU A CG 1 ATOM 5980 C CD1 . LEU A 1 740 ? 23.042 81.570 -26.346 1.00 20.21 ? 740 LEU A CD1 1 ATOM 5981 C CD2 . LEU A 1 740 ? 23.407 82.187 -23.924 1.00 19.05 ? 740 LEU A CD2 1 ATOM 5982 N N . GLY A 1 741 ? 21.309 87.012 -25.477 1.00 21.07 ? 741 GLY A N 1 ATOM 5983 C CA . GLY A 1 741 ? 21.387 88.267 -26.214 1.00 21.05 ? 741 GLY A CA 1 ATOM 5984 C C . GLY A 1 741 ? 21.958 88.029 -27.613 1.00 20.64 ? 741 GLY A C 1 ATOM 5985 O O . GLY A 1 741 ? 21.645 87.036 -28.263 1.00 21.63 ? 741 GLY A O 1 ATOM 5986 N N A GLN A 1 742 ? 22.809 88.944 -28.079 0.50 20.59 ? 742 GLN A N 1 ATOM 5987 N N B GLN A 1 742 ? 22.780 88.966 -28.071 0.50 20.50 ? 742 GLN A N 1 ATOM 5988 C CA A GLN A 1 742 ? 23.484 88.776 -29.372 0.50 19.95 ? 742 GLN A CA 1 ATOM 5989 C CA B GLN A 1 742 ? 23.491 88.820 -29.334 0.50 19.67 ? 742 GLN A CA 1 ATOM 5990 C C A GLN A 1 742 ? 25.018 88.746 -29.192 0.50 18.42 ? 742 GLN A C 1 ATOM 5991 C C B GLN A 1 742 ? 24.982 88.806 -28.973 0.50 18.35 ? 742 GLN A C 1 ATOM 5992 O O A GLN A 1 742 ? 25.719 89.712 -29.492 0.50 18.42 ? 742 GLN A O 1 ATOM 5993 O O B GLN A 1 742 ? 25.600 89.868 -28.826 0.50 17.88 ? 742 GLN A O 1 ATOM 5994 C CB A GLN A 1 742 ? 23.055 89.859 -30.374 0.50 20.26 ? 742 GLN A CB 1 ATOM 5995 C CB B GLN A 1 742 ? 23.160 89.984 -30.282 0.50 20.08 ? 742 GLN A CB 1 ATOM 5996 C CG A GLN A 1 742 ? 23.523 89.588 -31.799 0.50 21.91 ? 742 GLN A CG 1 ATOM 5997 C CG B GLN A 1 742 ? 21.687 90.077 -30.729 0.50 20.93 ? 742 GLN A CG 1 ATOM 5998 C CD A GLN A 1 742 ? 23.107 90.649 -32.817 0.50 22.10 ? 742 GLN A CD 1 ATOM 5999 C CD B GLN A 1 742 ? 21.461 91.182 -31.750 0.50 21.44 ? 742 GLN A CD 1 ATOM 6000 O OE1 A GLN A 1 742 ? 22.881 90.325 -33.982 0.50 24.90 ? 742 GLN A OE1 1 ATOM 6001 O OE1 B GLN A 1 742 ? 21.332 90.913 -32.945 0.50 25.38 ? 742 GLN A OE1 1 ATOM 6002 N NE2 A GLN A 1 742 ? 23.028 91.911 -32.390 0.50 24.63 ? 742 GLN A NE2 1 ATOM 6003 N NE2 B GLN A 1 742 ? 21.417 92.420 -31.284 0.50 24.77 ? 742 GLN A NE2 1 ATOM 6004 N N . PRO A 1 743 ? 25.543 87.618 -28.723 1.00 17.15 ? 743 PRO A N 1 ATOM 6005 C CA . PRO A 1 743 ? 26.937 87.559 -28.271 1.00 16.00 ? 743 PRO A CA 1 ATOM 6006 C C . PRO A 1 743 ? 27.938 87.752 -29.406 1.00 14.87 ? 743 PRO A C 1 ATOM 6007 O O . PRO A 1 743 ? 27.668 87.511 -30.597 1.00 16.74 ? 743 PRO A O 1 ATOM 6008 C CB . PRO A 1 743 ? 27.045 86.157 -27.651 1.00 15.75 ? 743 PRO A CB 1 ATOM 6009 C CG . PRO A 1 743 ? 26.021 85.369 -28.288 1.00 16.16 ? 743 PRO A CG 1 ATOM 6010 C CD . PRO A 1 743 ? 24.898 86.286 -28.701 1.00 16.40 ? 743 PRO A CD 1 ATOM 6011 N N . VAL A 1 744 ? 29.111 88.234 -29.011 1.00 13.06 ? 744 VAL A N 1 ATOM 6012 C CA . VAL A 1 744 ? 30.230 88.414 -29.938 1.00 12.47 ? 744 VAL A CA 1 ATOM 6013 C C . VAL A 1 744 ? 30.953 87.090 -30.163 1.00 11.55 ? 744 VAL A C 1 ATOM 6014 O O . VAL A 1 744 ? 31.293 86.389 -29.186 1.00 12.08 ? 744 VAL A O 1 ATOM 6015 C CB . VAL A 1 744 ? 31.214 89.455 -29.404 1.00 11.82 ? 744 VAL A CB 1 ATOM 6016 C CG1 . VAL A 1 744 ? 32.379 89.614 -30.325 1.00 13.41 ? 744 VAL A CG1 1 ATOM 6017 C CG2 . VAL A 1 744 ? 30.477 90.812 -29.167 1.00 15.13 ? 744 VAL A CG2 1 ATOM 6018 N N . VAL A 1 745 ? 31.141 86.728 -31.419 1.00 10.86 ? 745 VAL A N 1 ATOM 6019 C CA . VAL A 1 745 ? 31.760 85.463 -31.816 1.00 10.76 ? 745 VAL A CA 1 ATOM 6020 C C . VAL A 1 745 ? 33.069 85.736 -32.540 1.00 11.31 ? 745 VAL A C 1 ATOM 6021 O O . VAL A 1 745 ? 33.117 86.571 -33.473 1.00 11.43 ? 745 VAL A O 1 ATOM 6022 C CB . VAL A 1 745 ? 30.803 84.635 -32.711 1.00 11.23 ? 745 VAL A CB 1 ATOM 6023 C CG1 . VAL A 1 745 ? 31.458 83.321 -33.177 1.00 12.93 ? 745 VAL A CG1 1 ATOM 6024 C CG2 . VAL A 1 745 ? 29.521 84.376 -31.979 1.00 11.59 ? 745 VAL A CG2 1 ATOM 6025 N N . LEU A 1 746 ? 34.149 85.074 -32.139 1.00 10.22 ? 746 LEU A N 1 ATOM 6026 C CA . LEU A 1 746 ? 35.441 85.206 -32.786 1.00 10.09 ? 746 LEU A CA 1 ATOM 6027 C C . LEU A 1 746 ? 35.854 83.903 -33.430 1.00 10.47 ? 746 LEU A C 1 ATOM 6028 O O . LEU A 1 746 ? 35.936 82.859 -32.732 1.00 10.18 ? 746 LEU A O 1 ATOM 6029 C CB . LEU A 1 746 ? 36.486 85.609 -31.741 1.00 11.32 ? 746 LEU A CB 1 ATOM 6030 C CG . LEU A 1 746 ? 37.950 85.606 -32.189 1.00 12.63 ? 746 LEU A CG 1 ATOM 6031 C CD1 . LEU A 1 746 ? 38.191 86.686 -33.238 1.00 14.57 ? 746 LEU A CD1 1 ATOM 6032 C CD2 . LEU A 1 746 ? 38.835 85.842 -30.994 1.00 15.82 ? 746 LEU A CD2 1 ATOM 6033 N N . VAL A 1 747 ? 36.152 83.923 -34.708 1.00 9.64 ? 747 VAL A N 1 ATOM 6034 C CA . VAL A 1 747 ? 36.553 82.740 -35.445 1.00 10.69 ? 747 VAL A CA 1 ATOM 6035 C C . VAL A 1 747 ? 37.995 82.892 -35.850 1.00 11.60 ? 747 VAL A C 1 ATOM 6036 O O . VAL A 1 747 ? 38.356 83.843 -36.557 1.00 12.46 ? 747 VAL A O 1 ATOM 6037 C CB . VAL A 1 747 ? 35.674 82.561 -36.699 1.00 10.85 ? 747 VAL A CB 1 ATOM 6038 C CG1 . VAL A 1 747 ? 36.034 81.273 -37.398 1.00 12.38 ? 747 VAL A CG1 1 ATOM 6039 C CG2 . VAL A 1 747 ? 34.236 82.557 -36.319 1.00 12.48 ? 747 VAL A CG2 1 ATOM 6040 N N . THR A 1 748 ? 38.857 81.970 -35.457 1.00 11.26 ? 748 THR A N 1 ATOM 6041 C CA . THR A 1 748 ? 40.228 81.970 -35.894 1.00 12.40 ? 748 THR A CA 1 ATOM 6042 C C . THR A 1 748 ? 40.444 80.748 -36.755 1.00 12.61 ? 748 THR A C 1 ATOM 6043 O O . THR A 1 748 ? 40.125 79.629 -36.308 1.00 13.36 ? 748 THR A O 1 ATOM 6044 C CB . THR A 1 748 ? 41.145 81.995 -34.654 1.00 13.18 ? 748 THR A CB 1 ATOM 6045 O OG1 . THR A 1 748 ? 40.936 83.218 -33.934 1.00 14.28 ? 748 THR A OG1 1 ATOM 6046 C CG2 . THR A 1 748 ? 42.614 82.019 -35.060 1.00 14.56 ? 748 THR A CG2 1 ATOM 6047 N N . LYS A 1 749 ? 40.974 80.905 -37.972 1.00 12.43 ? 749 LYS A N 1 ATOM 6048 C CA . LYS A 1 749 ? 41.109 79.782 -38.895 1.00 13.79 ? 749 LYS A CA 1 ATOM 6049 C C . LYS A 1 749 ? 42.542 79.641 -39.288 1.00 13.25 ? 749 LYS A C 1 ATOM 6050 O O . LYS A 1 749 ? 43.156 80.574 -39.856 1.00 12.88 ? 749 LYS A O 1 ATOM 6051 C CB . LYS A 1 749 ? 40.269 79.974 -40.154 1.00 13.63 ? 749 LYS A CB 1 ATOM 6052 C CG . LYS A 1 749 ? 40.321 78.777 -41.112 1.00 16.06 ? 749 LYS A CG 1 ATOM 6053 C CD . LYS A 1 749 ? 39.479 79.051 -42.365 1.00 18.34 ? 749 LYS A CD 1 ATOM 6054 C CE . LYS A 1 749 ? 39.879 78.082 -43.466 1.00 23.97 ? 749 LYS A CE 1 ATOM 6055 N NZ . LYS A 1 749 ? 39.551 78.630 -44.814 1.00 29.70 ? 749 LYS A NZ 1 ATOM 6056 N N . GLY A 1 750 ? 43.119 78.492 -38.964 1.00 12.79 ? 750 GLY A N 1 ATOM 6057 C CA . GLY A 1 750 ? 44.505 78.241 -39.267 1.00 13.16 ? 750 GLY A CA 1 ATOM 6058 C C . GLY A 1 750 ? 44.703 76.855 -39.827 1.00 12.70 ? 750 GLY A C 1 ATOM 6059 O O . GLY A 1 750 ? 43.817 75.998 -39.729 1.00 13.86 ? 750 GLY A O 1 ATOM 6060 N N . LYS A 1 751 ? 45.879 76.639 -40.410 1.00 13.67 ? 751 LYS A N 1 ATOM 6061 C CA . LYS A 1 751 ? 46.217 75.354 -41.008 1.00 15.17 ? 751 LYS A CA 1 ATOM 6062 C C . LYS A 1 751 ? 46.329 74.264 -39.946 1.00 13.83 ? 751 LYS A C 1 ATOM 6063 O O . LYS A 1 751 ? 45.947 73.118 -40.211 1.00 14.20 ? 751 LYS A O 1 ATOM 6064 C CB . LYS A 1 751 ? 47.535 75.471 -41.768 1.00 16.68 ? 751 LYS A CB 1 ATOM 6065 C CG . LYS A 1 751 ? 47.956 74.204 -42.484 1.00 23.55 ? 751 LYS A CG 1 ATOM 6066 C CD . LYS A 1 751 ? 47.883 74.344 -44.006 1.00 31.25 ? 751 LYS A CD 1 ATOM 6067 C CE . LYS A 1 751 ? 48.379 73.067 -44.674 1.00 33.34 ? 751 LYS A CE 1 ATOM 6068 N NZ . LYS A 1 751 ? 49.645 72.568 -44.053 1.00 37.28 ? 751 LYS A NZ 1 ATOM 6069 N N . LEU A 1 752 ? 46.861 74.621 -38.772 1.00 13.31 ? 752 LEU A N 1 ATOM 6070 C CA . LEU A 1 752 ? 47.112 73.639 -37.689 1.00 12.39 ? 752 LEU A CA 1 ATOM 6071 C C . LEU A 1 752 ? 46.019 73.657 -36.624 1.00 13.00 ? 752 LEU A C 1 ATOM 6072 O O . LEU A 1 752 ? 45.713 72.636 -36.012 1.00 12.19 ? 752 LEU A O 1 ATOM 6073 C CB . LEU A 1 752 ? 48.473 73.894 -37.029 1.00 12.83 ? 752 LEU A CB 1 ATOM 6074 C CG . LEU A 1 752 ? 49.707 73.794 -37.938 1.00 15.11 ? 752 LEU A CG 1 ATOM 6075 C CD1 . LEU A 1 752 ? 51.005 73.935 -37.157 1.00 16.19 ? 752 LEU A CD1 1 ATOM 6076 C CD2 . LEU A 1 752 ? 49.730 72.541 -38.788 1.00 18.71 ? 752 LEU A CD2 1 ATOM 6077 N N . GLU A 1 753 ? 45.405 74.817 -36.394 1.00 12.31 ? 753 GLU A N 1 ATOM 6078 C CA . GLU A 1 753 ? 44.467 74.968 -35.290 1.00 12.62 ? 753 GLU A CA 1 ATOM 6079 C C . GLU A 1 753 ? 43.469 76.064 -35.640 1.00 11.96 ? 753 GLU A C 1 ATOM 6080 O O . GLU A 1 753 ? 43.877 77.175 -36.045 1.00 12.33 ? 753 GLU A O 1 ATOM 6081 C CB . GLU A 1 753 ? 45.220 75.336 -33.993 1.00 12.56 ? 753 GLU A CB 1 ATOM 6082 C CG . GLU A 1 753 ? 44.307 75.517 -32.780 1.00 14.65 ? 753 GLU A CG 1 ATOM 6083 C CD . GLU A 1 753 ? 45.021 76.169 -31.595 1.00 17.72 ? 753 GLU A CD 1 ATOM 6084 O OE1 . GLU A 1 753 ? 45.298 77.395 -31.645 1.00 25.79 ? 753 GLU A OE1 1 ATOM 6085 O OE2 . GLU A 1 753 ? 45.304 75.436 -30.642 1.00 24.39 ? 753 GLU A OE2 1 ATOM 6086 N N . SER A 1 754 ? 42.193 75.767 -35.495 1.00 10.33 ? 754 SER A N 1 ATOM 6087 C CA . SER A 1 754 ? 41.136 76.757 -35.662 1.00 10.14 ? 754 SER A CA 1 ATOM 6088 C C . SER A 1 754 ? 40.248 76.766 -34.436 1.00 9.84 ? 754 SER A C 1 ATOM 6089 O O . SER A 1 754 ? 40.240 75.796 -33.633 1.00 11.01 ? 754 SER A O 1 ATOM 6090 C CB . SER A 1 754 ? 40.302 76.422 -36.901 1.00 10.96 ? 754 SER A CB 1 ATOM 6091 O OG . SER A 1 754 ? 41.076 76.500 -38.064 1.00 11.54 ? 754 SER A OG 1 ATOM 6092 N N . SER A 1 755 ? 39.479 77.812 -34.223 1.00 9.80 ? 755 SER A N 1 ATOM 6093 C CA A SER A 1 755 ? 38.609 77.890 -33.069 0.50 10.38 ? 755 SER A CA 1 ATOM 6094 C CA B SER A 1 755 ? 38.591 77.866 -33.080 0.50 10.73 ? 755 SER A CA 1 ATOM 6095 C C . SER A 1 755 ? 37.440 78.833 -33.271 1.00 9.97 ? 755 SER A C 1 ATOM 6096 O O . SER A 1 755 ? 37.526 79.786 -34.096 1.00 10.74 ? 755 SER A O 1 ATOM 6097 C CB A SER A 1 755 ? 39.412 78.367 -31.862 0.50 11.68 ? 755 SER A CB 1 ATOM 6098 C CB B SER A 1 755 ? 39.369 78.228 -31.805 0.50 12.36 ? 755 SER A CB 1 ATOM 6099 O OG A SER A 1 755 ? 40.113 79.547 -32.172 0.50 10.82 ? 755 SER A OG 1 ATOM 6100 O OG B SER A 1 755 ? 39.619 79.615 -31.701 0.50 12.94 ? 755 SER A OG 1 ATOM 6101 N N . VAL A 1 756 ? 36.385 78.620 -32.514 1.00 9.36 ? 756 VAL A N 1 ATOM 6102 C CA . VAL A 1 756 ? 35.268 79.534 -32.435 1.00 9.77 ? 756 VAL A CA 1 ATOM 6103 C C . VAL A 1 756 ? 35.121 79.848 -30.965 1.00 9.86 ? 756 VAL A C 1 ATOM 6104 O O . VAL A 1 756 ? 34.924 78.913 -30.141 1.00 10.96 ? 756 VAL A O 1 ATOM 6105 C CB . VAL A 1 756 ? 33.984 78.916 -33.000 1.00 10.37 ? 756 VAL A CB 1 ATOM 6106 C CG1 . VAL A 1 756 ? 32.774 79.855 -32.777 1.00 12.20 ? 756 VAL A CG1 1 ATOM 6107 C CG2 . VAL A 1 756 ? 34.217 78.553 -34.472 1.00 11.99 ? 756 VAL A CG2 1 ATOM 6108 N N . SER A 1 757 ? 35.129 81.118 -30.600 1.00 9.69 ? 757 SER A N 1 ATOM 6109 C CA . SER A 1 757 ? 35.003 81.534 -29.194 1.00 9.93 ? 757 SER A CA 1 ATOM 6110 C C . SER A 1 757 ? 33.849 82.509 -29.087 1.00 10.21 ? 757 SER A C 1 ATOM 6111 O O . SER A 1 757 ? 33.703 83.366 -29.983 1.00 11.51 ? 757 SER A O 1 ATOM 6112 C CB . SER A 1 757 ? 36.285 82.260 -28.746 1.00 11.10 ? 757 SER A CB 1 ATOM 6113 O OG . SER A 1 757 ? 37.398 81.379 -28.876 1.00 13.65 ? 757 SER A OG 1 ATOM 6114 N N . VAL A 1 758 ? 33.042 82.444 -28.044 1.00 9.61 ? 758 VAL A N 1 ATOM 6115 C CA . VAL A 1 758 ? 31.917 83.363 -27.884 1.00 10.34 ? 758 VAL A CA 1 ATOM 6116 C C . VAL A 1 758 ? 31.805 83.818 -26.445 1.00 10.81 ? 758 VAL A C 1 ATOM 6117 O O . VAL A 1 758 ? 31.963 83.011 -25.509 1.00 10.08 ? 758 VAL A O 1 ATOM 6118 C CB . VAL A 1 758 ? 30.605 82.719 -28.392 1.00 10.60 ? 758 VAL A CB 1 ATOM 6119 C CG1 . VAL A 1 758 ? 30.316 81.365 -27.706 1.00 11.52 ? 758 VAL A CG1 1 ATOM 6120 C CG2 . VAL A 1 758 ? 29.435 83.676 -28.191 1.00 12.83 ? 758 VAL A CG2 1 ATOM 6121 N N . GLY A 1 759 ? 31.512 85.104 -26.236 1.00 11.04 ? 759 GLY A N 1 ATOM 6122 C CA . GLY A 1 759 ? 31.399 85.675 -24.903 1.00 12.55 ? 759 GLY A CA 1 ATOM 6123 C C . GLY A 1 759 ? 29.954 85.608 -24.464 1.00 12.74 ? 759 GLY A C 1 ATOM 6124 O O . GLY A 1 759 ? 29.138 86.485 -24.791 1.00 13.03 ? 759 GLY A O 1 ATOM 6125 N N . LEU A 1 760 ? 29.589 84.569 -23.734 1.00 12.95 ? 760 LEU A N 1 ATOM 6126 C CA . LEU A 1 760 ? 28.237 84.409 -23.215 1.00 13.86 ? 760 LEU A CA 1 ATOM 6127 C C . LEU A 1 760 ? 28.165 84.956 -21.815 1.00 13.33 ? 760 LEU A C 1 ATOM 6128 O O . LEU A 1 760 ? 29.205 85.116 -21.151 1.00 14.00 ? 760 LEU A O 1 ATOM 6129 C CB . LEU A 1 760 ? 27.878 82.928 -23.178 1.00 13.96 ? 760 LEU A CB 1 ATOM 6130 C CG . LEU A 1 760 ? 28.000 82.223 -24.514 1.00 13.86 ? 760 LEU A CG 1 ATOM 6131 C CD1 . LEU A 1 760 ? 27.777 80.720 -24.366 1.00 15.84 ? 760 LEU A CD1 1 ATOM 6132 C CD2 . LEU A 1 760 ? 27.059 82.787 -25.609 1.00 17.24 ? 760 LEU A CD2 1 ATOM 6133 N N . PRO A 1 761 ? 26.970 85.229 -21.296 1.00 14.59 ? 761 PRO A N 1 ATOM 6134 C CA . PRO A 1 761 ? 26.862 85.611 -19.886 1.00 14.99 ? 761 PRO A CA 1 ATOM 6135 C C . PRO A 1 761 ? 27.450 84.496 -19.013 1.00 14.56 ? 761 PRO A C 1 ATOM 6136 O O . PRO A 1 761 ? 27.003 83.350 -19.048 1.00 15.33 ? 761 PRO A O 1 ATOM 6137 C CB . PRO A 1 761 ? 25.343 85.768 -19.667 1.00 16.25 ? 761 PRO A CB 1 ATOM 6138 C CG . PRO A 1 761 ? 24.826 86.103 -21.037 1.00 16.43 ? 761 PRO A CG 1 ATOM 6139 C CD . PRO A 1 761 ? 25.662 85.269 -21.975 1.00 14.55 ? 761 PRO A CD 1 ATOM 6140 N N . SER A 1 762 ? 28.444 84.895 -18.228 1.00 14.22 ? 762 SER A N 1 ATOM 6141 C CA . SER A 1 762 ? 29.171 84.051 -17.281 1.00 13.72 ? 762 SER A CA 1 ATOM 6142 C C . SER A 1 762 ? 30.124 83.042 -17.886 1.00 12.25 ? 762 SER A C 1 ATOM 6143 O O . SER A 1 762 ? 30.796 82.343 -17.122 1.00 12.20 ? 762 SER A O 1 ATOM 6144 C CB . SER A 1 762 ? 28.247 83.258 -16.368 1.00 13.94 ? 762 SER A CB 1 ATOM 6145 O OG . SER A 1 762 ? 27.295 84.058 -15.689 1.00 17.86 ? 762 SER A OG 1 ATOM 6146 N N . VAL A 1 763 ? 30.188 82.921 -19.197 1.00 11.02 ? 763 VAL A N 1 ATOM 6147 C CA . VAL A 1 763 ? 31.058 81.917 -19.805 1.00 11.04 ? 763 VAL A CA 1 ATOM 6148 C C . VAL A 1 763 ? 31.660 82.382 -21.104 1.00 10.49 ? 763 VAL A C 1 ATOM 6149 O O . VAL A 1 763 ? 30.915 82.741 -22.011 1.00 11.09 ? 763 VAL A O 1 ATOM 6150 C CB . VAL A 1 763 ? 30.284 80.603 -20.104 1.00 12.74 ? 763 VAL A CB 1 ATOM 6151 C CG1 . VAL A 1 763 ? 31.221 79.546 -20.641 1.00 12.26 ? 763 VAL A CG1 1 ATOM 6152 C CG2 . VAL A 1 763 ? 29.567 80.033 -18.894 1.00 14.94 ? 763 VAL A CG2 1 ATOM 6153 N N . VAL A 1 764 ? 32.980 82.390 -21.230 1.00 8.93 ? 764 VAL A N 1 ATOM 6154 C CA . VAL A 1 764 ? 33.580 82.475 -22.545 1.00 9.15 ? 764 VAL A CA 1 ATOM 6155 C C . VAL A 1 764 ? 33.759 81.030 -23.010 1.00 9.53 ? 764 VAL A C 1 ATOM 6156 O O . VAL A 1 764 ? 34.541 80.277 -22.401 1.00 8.91 ? 764 VAL A O 1 ATOM 6157 C CB . VAL A 1 764 ? 34.935 83.237 -22.561 1.00 9.91 ? 764 VAL A CB 1 ATOM 6158 C CG1 . VAL A 1 764 ? 35.463 83.270 -23.988 1.00 11.24 ? 764 VAL A CG1 1 ATOM 6159 C CG2 . VAL A 1 764 ? 34.758 84.671 -22.025 1.00 11.53 ? 764 VAL A CG2 1 ATOM 6160 N N . HIS A 1 765 ? 33.031 80.646 -24.045 1.00 9.43 ? 765 HIS A N 1 ATOM 6161 C CA . HIS A 1 765 ? 32.952 79.252 -24.506 1.00 9.39 ? 765 HIS A CA 1 ATOM 6162 C C . HIS A 1 765 ? 33.768 79.138 -25.781 1.00 10.00 ? 765 HIS A C 1 ATOM 6163 O O . HIS A 1 765 ? 33.602 79.977 -26.704 1.00 10.39 ? 765 HIS A O 1 ATOM 6164 C CB . HIS A 1 765 ? 31.476 78.925 -24.738 1.00 9.86 ? 765 HIS A CB 1 ATOM 6165 C CG . HIS A 1 765 ? 31.223 77.637 -25.428 1.00 9.19 ? 765 HIS A CG 1 ATOM 6166 N ND1 . HIS A 1 765 ? 31.435 76.409 -24.821 1.00 9.41 ? 765 HIS A ND1 1 ATOM 6167 C CD2 . HIS A 1 765 ? 30.727 77.378 -26.661 1.00 10.95 ? 765 HIS A CD2 1 ATOM 6168 C CE1 . HIS A 1 765 ? 31.075 75.454 -25.664 1.00 11.13 ? 765 HIS A CE1 1 ATOM 6169 N NE2 . HIS A 1 765 ? 30.644 76.017 -26.793 1.00 11.57 ? 765 HIS A NE2 1 ATOM 6170 N N . GLN A 1 766 ? 34.670 78.172 -25.857 1.00 8.95 ? 766 GLN A N 1 ATOM 6171 C CA A GLN A 1 766 ? 35.590 78.034 -26.971 0.50 9.55 ? 766 GLN A CA 1 ATOM 6172 C CA B GLN A 1 766 ? 35.560 78.031 -26.984 0.50 9.52 ? 766 GLN A CA 1 ATOM 6173 C C . GLN A 1 766 ? 35.575 76.605 -27.485 1.00 9.58 ? 766 GLN A C 1 ATOM 6174 O O . GLN A 1 766 ? 35.669 75.651 -26.685 1.00 9.80 ? 766 GLN A O 1 ATOM 6175 C CB A GLN A 1 766 ? 37.015 78.400 -26.545 0.50 9.88 ? 766 GLN A CB 1 ATOM 6176 C CB B GLN A 1 766 ? 36.974 78.448 -26.607 0.50 9.65 ? 766 GLN A CB 1 ATOM 6177 C CG A GLN A 1 766 ? 37.129 79.730 -25.792 0.50 10.29 ? 766 GLN A CG 1 ATOM 6178 C CG B GLN A 1 766 ? 37.931 78.463 -27.773 0.50 10.19 ? 766 GLN A CG 1 ATOM 6179 C CD A GLN A 1 766 ? 38.116 79.692 -24.596 0.50 15.56 ? 766 GLN A CD 1 ATOM 6180 C CD B GLN A 1 766 ? 39.353 78.838 -27.381 0.50 13.08 ? 766 GLN A CD 1 ATOM 6181 O OE1 A GLN A 1 766 ? 39.293 79.417 -24.805 0.50 14.05 ? 766 GLN A OE1 1 ATOM 6182 O OE1 B GLN A 1 766 ? 39.743 78.708 -26.215 0.50 16.36 ? 766 GLN A OE1 1 ATOM 6183 N NE2 A GLN A 1 766 ? 37.631 79.962 -23.352 0.50 13.46 ? 766 GLN A NE2 1 ATOM 6184 N NE2 B GLN A 1 766 ? 40.131 79.307 -28.356 0.50 13.23 ? 766 GLN A NE2 1 ATOM 6185 N N . THR A 1 767 ? 35.454 76.440 -28.790 1.00 8.60 ? 767 THR A N 1 ATOM 6186 C CA . THR A 1 767 ? 35.604 75.144 -29.457 1.00 9.69 ? 767 THR A CA 1 ATOM 6187 C C . THR A 1 767 ? 36.838 75.183 -30.302 1.00 9.43 ? 767 THR A C 1 ATOM 6188 O O . THR A 1 767 ? 36.946 76.069 -31.167 1.00 10.21 ? 767 THR A O 1 ATOM 6189 C CB . THR A 1 767 ? 34.401 74.867 -30.340 1.00 9.94 ? 767 THR A CB 1 ATOM 6190 O OG1 . THR A 1 767 ? 33.215 74.936 -29.547 1.00 12.29 ? 767 THR A OG1 1 ATOM 6191 C CG2 . THR A 1 767 ? 34.463 73.430 -30.915 1.00 10.78 ? 767 THR A CG2 1 ATOM 6192 N N . ILE A 1 768 ? 37.808 74.312 -30.045 1.00 9.75 ? 768 ILE A N 1 ATOM 6193 C CA . ILE A 1 768 ? 39.097 74.309 -30.701 1.00 9.99 ? 768 ILE A CA 1 ATOM 6194 C C . ILE A 1 768 ? 39.264 73.034 -31.520 1.00 10.61 ? 768 ILE A C 1 ATOM 6195 O O . ILE A 1 768 ? 38.926 71.930 -31.037 1.00 11.33 ? 768 ILE A O 1 ATOM 6196 C CB . ILE A 1 768 ? 40.238 74.400 -29.668 1.00 9.88 ? 768 ILE A CB 1 ATOM 6197 C CG1 . ILE A 1 768 ? 40.049 75.636 -28.805 1.00 11.86 ? 768 ILE A CG1 1 ATOM 6198 C CG2 . ILE A 1 768 ? 41.589 74.443 -30.333 1.00 12.33 ? 768 ILE A CG2 1 ATOM 6199 C CD1 . ILE A 1 768 ? 40.838 75.641 -27.480 1.00 14.36 ? 768 ILE A CD1 1 ATOM 6200 N N . MET A 1 769 ? 39.765 73.190 -32.735 1.00 10.45 ? 769 MET A N 1 ATOM 6201 C CA A MET A 1 769 ? 39.903 72.091 -33.683 0.50 11.07 ? 769 MET A CA 1 ATOM 6202 C CA B MET A 1 769 ? 39.903 72.094 -33.687 0.50 11.42 ? 769 MET A CA 1 ATOM 6203 C C . MET A 1 769 ? 41.346 71.973 -34.097 1.00 11.90 ? 769 MET A C 1 ATOM 6204 O O . MET A 1 769 ? 41.942 72.929 -34.551 1.00 11.16 ? 769 MET A O 1 ATOM 6205 C CB A MET A 1 769 ? 39.045 72.351 -34.911 0.50 12.14 ? 769 MET A CB 1 ATOM 6206 C CB B MET A 1 769 ? 39.056 72.357 -34.923 0.50 12.48 ? 769 MET A CB 1 ATOM 6207 C CG A MET A 1 769 ? 37.590 72.365 -34.566 0.50 10.21 ? 769 MET A CG 1 ATOM 6208 C CG B MET A 1 769 ? 37.594 72.227 -34.637 0.50 11.73 ? 769 MET A CG 1 ATOM 6209 S SD A MET A 1 769 ? 36.605 73.000 -35.900 0.50 13.82 ? 769 MET A SD 1 ATOM 6210 S SD B MET A 1 769 ? 36.603 73.014 -35.890 0.50 14.80 ? 769 MET A SD 1 ATOM 6211 C CE A MET A 1 769 ? 36.844 71.656 -37.066 0.50 11.57 ? 769 MET A CE 1 ATOM 6212 C CE B MET A 1 769 ? 36.473 74.636 -35.139 0.50 18.41 ? 769 MET A CE 1 ATOM 6213 N N . ARG A 1 770 ? 41.891 70.777 -33.949 1.00 12.46 ? 770 ARG A N 1 ATOM 6214 C CA A ARG A 1 770 ? 43.258 70.553 -34.355 0.50 13.92 ? 770 ARG A CA 1 ATOM 6215 C CA B ARG A 1 770 ? 43.252 70.524 -34.380 0.50 13.53 ? 770 ARG A CA 1 ATOM 6216 C C . ARG A 1 770 ? 43.365 69.373 -35.343 1.00 15.03 ? 770 ARG A C 1 ATOM 6217 O O . ARG A 1 770 ? 44.484 68.895 -35.589 1.00 16.98 ? 770 ARG A O 1 ATOM 6218 C CB A ARG A 1 770 ? 44.180 70.394 -33.123 0.50 14.13 ? 770 ARG A CB 1 ATOM 6219 C CB B ARG A 1 770 ? 44.126 70.171 -33.210 0.50 13.64 ? 770 ARG A CB 1 ATOM 6220 C CG A ARG A 1 770 ? 44.015 71.483 -32.029 0.50 14.76 ? 770 ARG A CG 1 ATOM 6221 C CG B ARG A 1 770 ? 44.494 71.297 -32.344 0.50 13.00 ? 770 ARG A CG 1 ATOM 6222 C CD A ARG A 1 770 ? 45.016 71.408 -30.853 0.50 14.48 ? 770 ARG A CD 1 ATOM 6223 C CD B ARG A 1 770 ? 45.343 70.828 -31.175 0.50 11.17 ? 770 ARG A CD 1 ATOM 6224 N NE A ARG A 1 770 ? 44.824 72.468 -29.863 0.50 16.79 ? 770 ARG A NE 1 ATOM 6225 N NE B ARG A 1 770 ? 44.645 69.849 -30.343 0.50 13.41 ? 770 ARG A NE 1 ATOM 6226 C CZ A ARG A 1 770 ? 44.200 72.324 -28.690 0.50 16.00 ? 770 ARG A CZ 1 ATOM 6227 C CZ B ARG A 1 770 ? 43.814 70.163 -29.368 0.50 13.60 ? 770 ARG A CZ 1 ATOM 6228 N NH1 A ARG A 1 770 ? 43.694 71.147 -28.316 0.50 15.50 ? 770 ARG A NH1 1 ATOM 6229 N NH1 B ARG A 1 770 ? 43.535 71.437 -29.106 0.50 14.75 ? 770 ARG A NH1 1 ATOM 6230 N NH2 A ARG A 1 770 ? 44.093 73.364 -27.873 0.50 16.72 ? 770 ARG A NH2 1 ATOM 6231 N NH2 B ARG A 1 770 ? 43.241 69.189 -28.673 0.50 13.73 ? 770 ARG A NH2 1 ATOM 6232 N N . GLY A 1 771 ? 42.225 68.921 -35.865 1.00 15.01 ? 771 GLY A N 1 ATOM 6233 C CA . GLY A 1 771 ? 42.222 67.857 -36.854 1.00 17.28 ? 771 GLY A CA 1 ATOM 6234 C C . GLY A 1 771 ? 41.611 66.553 -36.388 1.00 17.91 ? 771 GLY A C 1 ATOM 6235 O O . GLY A 1 771 ? 41.434 65.640 -37.193 1.00 19.60 ? 771 GLY A O 1 ATOM 6236 N N . GLY A 1 772 ? 41.272 66.461 -35.102 1.00 17.60 ? 772 GLY A N 1 ATOM 6237 C CA . GLY A 1 772 ? 40.634 65.282 -34.502 1.00 17.47 ? 772 GLY A CA 1 ATOM 6238 C C . GLY A 1 772 ? 39.446 65.728 -33.657 1.00 16.59 ? 772 GLY A C 1 ATOM 6239 O O . GLY A 1 772 ? 38.752 66.680 -34.000 1.00 16.69 ? 772 GLY A O 1 ATOM 6240 N N . ALA A 1 773 ? 39.176 65.028 -32.546 1.00 15.06 ? 773 ALA A N 1 ATOM 6241 C CA . ALA A 1 773 ? 38.088 65.413 -31.652 1.00 13.70 ? 773 ALA A CA 1 ATOM 6242 C C . ALA A 1 773 ? 38.278 66.862 -31.188 1.00 12.03 ? 773 ALA A C 1 ATOM 6243 O O . ALA A 1 773 ? 39.378 67.214 -30.784 1.00 11.38 ? 773 ALA A O 1 ATOM 6244 C CB . ALA A 1 773 ? 38.055 64.508 -30.437 1.00 14.77 ? 773 ALA A CB 1 ATOM 6245 N N . PRO A 1 774 ? 37.235 67.681 -31.215 1.00 11.22 ? 774 PRO A N 1 ATOM 6246 C CA . PRO A 1 774 ? 37.413 69.057 -30.713 1.00 10.59 ? 774 PRO A CA 1 ATOM 6247 C C . PRO A 1 774 ? 37.725 69.109 -29.219 1.00 9.86 ? 774 PRO A C 1 ATOM 6248 O O . PRO A 1 774 ? 37.449 68.143 -28.467 1.00 9.61 ? 774 PRO A O 1 ATOM 6249 C CB . PRO A 1 774 ? 36.049 69.733 -30.967 1.00 12.19 ? 774 PRO A CB 1 ATOM 6250 C CG . PRO A 1 774 ? 35.096 68.667 -31.237 1.00 15.37 ? 774 PRO A CG 1 ATOM 6251 C CD . PRO A 1 774 ? 35.879 67.439 -31.746 1.00 11.87 ? 774 PRO A CD 1 ATOM 6252 N N . GLU A 1 775 ? 38.308 70.215 -28.824 1.00 9.61 ? 775 GLU A N 1 ATOM 6253 C CA . GLU A 1 775 ? 38.547 70.541 -27.436 1.00 9.20 ? 775 GLU A CA 1 ATOM 6254 C C . GLU A 1 775 ? 37.597 71.678 -27.095 1.00 8.54 ? 775 GLU A C 1 ATOM 6255 O O . GLU A 1 775 ? 37.396 72.618 -27.939 1.00 10.59 ? 775 GLU A O 1 ATOM 6256 C CB . GLU A 1 775 ? 39.995 70.945 -27.228 1.00 9.21 ? 775 GLU A CB 1 ATOM 6257 C CG . GLU A 1 775 ? 40.299 71.399 -25.799 1.00 11.32 ? 775 GLU A CG 1 ATOM 6258 C CD . GLU A 1 775 ? 41.770 71.626 -25.545 1.00 17.73 ? 775 GLU A CD 1 ATOM 6259 O OE1 . GLU A 1 775 ? 42.614 70.880 -26.088 1.00 21.50 ? 775 GLU A OE1 1 ATOM 6260 O OE2 . GLU A 1 775 ? 42.102 72.518 -24.759 1.00 20.44 ? 775 GLU A OE2 1 ATOM 6261 N N . ILE A 1 776 ? 36.929 71.623 -25.960 1.00 7.91 ? 776 ILE A N 1 ATOM 6262 C CA . ILE A 1 776 ? 36.076 72.686 -25.489 1.00 8.69 ? 776 ILE A CA 1 ATOM 6263 C C . ILE A 1 776 ? 36.748 73.306 -24.295 1.00 8.36 ? 776 ILE A C 1 ATOM 6264 O O . ILE A 1 776 ? 37.207 72.590 -23.392 1.00 8.34 ? 776 ILE A O 1 ATOM 6265 C CB . ILE A 1 776 ? 34.681 72.152 -25.069 1.00 9.41 ? 776 ILE A CB 1 ATOM 6266 C CG1 . ILE A 1 776 ? 34.070 71.236 -26.155 1.00 13.74 ? 776 ILE A CG1 1 ATOM 6267 C CG2 . ILE A 1 776 ? 33.784 73.328 -24.596 1.00 11.14 ? 776 ILE A CG2 1 ATOM 6268 C CD1 . ILE A 1 776 ? 33.921 71.865 -27.531 1.00 16.97 ? 776 ILE A CD1 1 ATOM 6269 N N . ARG A 1 777 ? 36.795 74.630 -24.230 1.00 8.32 ? 777 ARG A N 1 ATOM 6270 C CA . ARG A 1 777 ? 37.256 75.324 -23.030 1.00 8.72 ? 777 ARG A CA 1 ATOM 6271 C C . ARG A 1 777 ? 36.207 76.318 -22.598 1.00 8.94 ? 777 ARG A C 1 ATOM 6272 O O . ARG A 1 777 ? 35.722 77.118 -23.456 1.00 9.66 ? 777 ARG A O 1 ATOM 6273 C CB . ARG A 1 777 ? 38.562 76.082 -23.272 1.00 10.12 ? 777 ARG A CB 1 ATOM 6274 C CG . ARG A 1 777 ? 39.721 75.224 -23.618 1.00 10.34 ? 777 ARG A CG 1 ATOM 6275 C CD . ARG A 1 777 ? 40.988 76.021 -23.772 1.00 11.01 ? 777 ARG A CD 1 ATOM 6276 N NE . ARG A 1 777 ? 42.085 75.185 -24.240 1.00 13.77 ? 777 ARG A NE 1 ATOM 6277 C CZ . ARG A 1 777 ? 43.274 75.651 -24.579 1.00 18.49 ? 777 ARG A CZ 1 ATOM 6278 N NH1 . ARG A 1 777 ? 43.541 76.958 -24.439 1.00 20.22 ? 777 ARG A NH1 1 ATOM 6279 N NH2 . ARG A 1 777 ? 44.212 74.825 -25.040 1.00 21.03 ? 777 ARG A NH2 1 ATOM 6280 N N . ASN A 1 778 ? 35.843 76.335 -21.339 1.00 8.05 ? 778 ASN A N 1 ATOM 6281 C CA . ASN A 1 778 ? 34.908 77.304 -20.811 1.00 7.88 ? 778 ASN A CA 1 ATOM 6282 C C . ASN A 1 778 ? 35.614 78.112 -19.749 1.00 8.17 ? 778 ASN A C 1 ATOM 6283 O O . ASN A 1 778 ? 36.029 77.545 -18.711 1.00 8.61 ? 778 ASN A O 1 ATOM 6284 C CB . ASN A 1 778 ? 33.698 76.625 -20.145 1.00 8.25 ? 778 ASN A CB 1 ATOM 6285 C CG . ASN A 1 778 ? 32.758 75.966 -21.129 1.00 9.34 ? 778 ASN A CG 1 ATOM 6286 O OD1 . ASN A 1 778 ? 32.704 76.333 -22.307 1.00 10.45 ? 778 ASN A OD1 1 ATOM 6287 N ND2 . ASN A 1 778 ? 31.976 74.992 -20.623 1.00 8.88 ? 778 ASN A ND2 1 ATOM 6288 N N . LEU A 1 779 ? 35.686 79.439 -19.949 1.00 8.45 ? 779 LEU A N 1 ATOM 6289 C CA . LEU A 1 779 ? 36.139 80.320 -18.863 1.00 9.08 ? 779 LEU A CA 1 ATOM 6290 C C . LEU A 1 779 ? 34.897 80.758 -18.119 1.00 8.76 ? 779 LEU A C 1 ATOM 6291 O O . LEU A 1 779 ? 34.086 81.542 -18.657 1.00 9.61 ? 779 LEU A O 1 ATOM 6292 C CB . LEU A 1 779 ? 36.923 81.513 -19.439 1.00 10.02 ? 779 LEU A CB 1 ATOM 6293 C CG . LEU A 1 779 ? 37.479 82.512 -18.413 1.00 13.38 ? 779 LEU A CG 1 ATOM 6294 C CD1 . LEU A 1 779 ? 38.469 81.844 -17.518 1.00 16.34 ? 779 LEU A CD1 1 ATOM 6295 C CD2 . LEU A 1 779 ? 38.080 83.736 -19.140 1.00 15.45 ? 779 LEU A CD2 1 ATOM 6296 N N . VAL A 1 780 ? 34.682 80.186 -16.945 1.00 8.61 ? 780 VAL A N 1 ATOM 6297 C CA . VAL A 1 780 ? 33.425 80.320 -16.214 1.00 9.77 ? 780 VAL A CA 1 ATOM 6298 C C . VAL A 1 780 ? 33.581 81.318 -15.070 1.00 10.22 ? 780 VAL A C 1 ATOM 6299 O O . VAL A 1 780 ? 34.392 81.117 -14.164 1.00 10.08 ? 780 VAL A O 1 ATOM 6300 C CB . VAL A 1 780 ? 32.948 78.937 -15.663 1.00 9.53 ? 780 VAL A CB 1 ATOM 6301 C CG1 . VAL A 1 780 ? 31.622 79.069 -14.933 1.00 10.48 ? 780 VAL A CG1 1 ATOM 6302 C CG2 . VAL A 1 780 ? 32.891 77.904 -16.780 1.00 10.38 ? 780 VAL A CG2 1 ATOM 6303 N N . ASP A 1 781 ? 32.815 82.406 -15.146 1.00 10.12 ? 781 ASP A N 1 ATOM 6304 C CA . ASP A 1 781 ? 32.811 83.405 -14.092 1.00 10.63 ? 781 ASP A CA 1 ATOM 6305 C C . ASP A 1 781 ? 31.392 83.736 -13.725 1.00 11.51 ? 781 ASP A C 1 ATOM 6306 O O . ASP A 1 781 ? 30.729 84.585 -14.382 1.00 12.02 ? 781 ASP A O 1 ATOM 6307 C CB . ASP A 1 781 ? 33.522 84.669 -14.567 1.00 12.21 ? 781 ASP A CB 1 ATOM 6308 C CG . ASP A 1 781 ? 33.610 85.716 -13.475 1.00 13.08 ? 781 ASP A CG 1 ATOM 6309 O OD1 . ASP A 1 781 ? 33.116 85.498 -12.341 1.00 13.84 ? 781 ASP A OD1 1 ATOM 6310 O OD2 . ASP A 1 781 ? 34.192 86.813 -13.680 1.00 19.89 ? 781 ASP A OD2 1 ATOM 6311 N N . ILE A 1 782 ? 30.875 83.046 -12.732 1.00 11.56 ? 782 ILE A N 1 ATOM 6312 C CA . ILE A 1 782 ? 29.473 83.175 -12.338 1.00 13.35 ? 782 ILE A CA 1 ATOM 6313 C C . ILE A 1 782 ? 29.201 84.511 -11.662 1.00 14.82 ? 782 ILE A C 1 ATOM 6314 O O . ILE A 1 782 ? 28.040 84.867 -11.429 1.00 16.10 ? 782 ILE A O 1 ATOM 6315 C CB . ILE A 1 782 ? 29.108 81.973 -11.425 1.00 13.48 ? 782 ILE A CB 1 ATOM 6316 C CG1 . ILE A 1 782 ? 27.605 81.828 -11.196 1.00 14.61 ? 782 ILE A CG1 1 ATOM 6317 C CG2 . ILE A 1 782 ? 29.820 82.077 -10.082 1.00 14.19 ? 782 ILE A CG2 1 ATOM 6318 C CD1 . ILE A 1 782 ? 27.275 80.430 -10.745 1.00 16.23 ? 782 ILE A CD1 1 ATOM 6319 N N . GLY A 1 783 ? 30.260 85.259 -11.355 1.00 15.37 ? 783 GLY A N 1 ATOM 6320 C CA . GLY A 1 783 ? 30.120 86.657 -10.938 1.00 17.15 ? 783 GLY A CA 1 ATOM 6321 C C . GLY A 1 783 ? 29.284 86.741 -9.683 1.00 17.99 ? 783 GLY A C 1 ATOM 6322 O O . GLY A 1 783 ? 29.510 85.989 -8.740 1.00 19.52 ? 783 GLY A O 1 ATOM 6323 N N . SER A 1 784 ? 28.285 87.616 -9.685 1.00 20.09 ? 784 SER A N 1 ATOM 6324 C CA . SER A 1 784 ? 27.464 87.782 -8.489 1.00 20.97 ? 784 SER A CA 1 ATOM 6325 C C . SER A 1 784 ? 26.073 87.164 -8.644 1.00 20.76 ? 784 SER A C 1 ATOM 6326 O O . SER A 1 784 ? 25.126 87.577 -7.954 1.00 21.63 ? 784 SER A O 1 ATOM 6327 C CB . SER A 1 784 ? 27.352 89.258 -8.113 1.00 22.13 ? 784 SER A CB 1 ATOM 6328 O OG . SER A 1 784 ? 26.807 90.002 -9.191 1.00 26.30 ? 784 SER A OG 1 ATOM 6329 N N . LEU A 1 785 ? 25.940 86.175 -9.534 1.00 19.93 ? 785 LEU A N 1 ATOM 6330 C CA . LEU A 1 785 ? 24.646 85.511 -9.717 1.00 19.78 ? 785 LEU A CA 1 ATOM 6331 C C . LEU A 1 785 ? 24.302 84.562 -8.573 1.00 20.40 ? 785 LEU A C 1 ATOM 6332 O O . LEU A 1 785 ? 24.561 83.345 -8.637 1.00 21.36 ? 785 LEU A O 1 ATOM 6333 C CB . LEU A 1 785 ? 24.597 84.736 -11.029 1.00 19.61 ? 785 LEU A CB 1 ATOM 6334 C CG . LEU A 1 785 ? 24.827 85.446 -12.365 1.00 20.14 ? 785 LEU A CG 1 ATOM 6335 C CD1 . LEU A 1 785 ? 24.800 84.428 -13.497 1.00 23.34 ? 785 LEU A CD1 1 ATOM 6336 C CD2 . LEU A 1 785 ? 23.824 86.567 -12.612 1.00 23.41 ? 785 LEU A CD2 1 ATOM 6337 N N . ASP A 1 786 ? 23.639 85.080 -7.547 1.00 20.24 ? 786 ASP A N 1 ATOM 6338 C CA . ASP A 1 786 ? 23.337 84.246 -6.396 1.00 19.65 ? 786 ASP A CA 1 ATOM 6339 C C . ASP A 1 786 ? 22.271 83.204 -6.735 1.00 16.82 ? 786 ASP A C 1 ATOM 6340 O O . ASP A 1 786 ? 21.424 83.394 -7.611 1.00 17.66 ? 786 ASP A O 1 ATOM 6341 C CB . ASP A 1 786 ? 22.904 85.057 -5.173 1.00 21.02 ? 786 ASP A CB 1 ATOM 6342 C CG . ASP A 1 786 ? 23.843 86.189 -4.872 1.00 25.60 ? 786 ASP A CG 1 ATOM 6343 O OD1 . ASP A 1 786 ? 25.086 85.972 -4.773 1.00 25.15 ? 786 ASP A OD1 1 ATOM 6344 O OD2 . ASP A 1 786 ? 23.414 87.357 -4.751 1.00 32.10 ? 786 ASP A OD2 1 ATOM 6345 N N . ASN A 1 787 ? 22.383 82.085 -6.040 1.00 15.49 ? 787 ASN A N 1 ATOM 6346 C CA . ASN A 1 787 ? 21.424 80.989 -6.133 1.00 14.09 ? 787 ASN A CA 1 ATOM 6347 C C . ASN A 1 787 ? 21.247 80.529 -7.559 1.00 13.73 ? 787 ASN A C 1 ATOM 6348 O O . ASN A 1 787 ? 20.143 80.356 -8.052 1.00 14.18 ? 787 ASN A O 1 ATOM 6349 C CB . ASN A 1 787 ? 20.112 81.356 -5.422 1.00 14.76 ? 787 ASN A CB 1 ATOM 6350 C CG . ASN A 1 787 ? 20.337 81.580 -3.969 1.00 19.48 ? 787 ASN A CG 1 ATOM 6351 O OD1 . ASN A 1 787 ? 21.042 80.793 -3.325 1.00 18.68 ? 787 ASN A OD1 1 ATOM 6352 N ND2 . ASN A 1 787 ? 19.785 82.674 -3.431 1.00 25.64 ? 787 ASN A ND2 1 ATOM 6353 N N . THR A 1 788 ? 22.387 80.325 -8.218 1.00 11.88 ? 788 THR A N 1 ATOM 6354 C CA . THR A 1 788 ? 22.431 79.915 -9.610 1.00 12.39 ? 788 THR A CA 1 ATOM 6355 C C . THR A 1 788 ? 23.448 78.784 -9.804 1.00 10.77 ? 788 THR A C 1 ATOM 6356 O O . THR A 1 788 ? 24.533 78.851 -9.240 1.00 11.12 ? 788 THR A O 1 ATOM 6357 C CB . THR A 1 788 ? 22.863 81.108 -10.477 1.00 13.33 ? 788 THR A CB 1 ATOM 6358 O OG1 . THR A 1 788 ? 21.873 82.158 -10.363 1.00 15.69 ? 788 THR A OG1 1 ATOM 6359 C CG2 . THR A 1 788 ? 22.834 80.741 -11.949 1.00 15.53 ? 788 THR A CG2 1 ATOM 6360 N N . GLU A 1 789 ? 23.064 77.781 -10.579 1.00 9.41 ? 789 GLU A N 1 ATOM 6361 C CA . GLU A 1 789 ? 24.022 76.762 -11.023 1.00 9.83 ? 789 GLU A CA 1 ATOM 6362 C C . GLU A 1 789 ? 24.000 76.783 -12.531 1.00 10.24 ? 789 GLU A C 1 ATOM 6363 O O . GLU A 1 789 ? 22.916 76.664 -13.134 1.00 11.12 ? 789 GLU A O 1 ATOM 6364 C CB . GLU A 1 789 ? 23.682 75.358 -10.463 1.00 10.48 ? 789 GLU A CB 1 ATOM 6365 C CG . GLU A 1 789 ? 23.234 75.391 -9.015 1.00 11.00 ? 789 GLU A CG 1 ATOM 6366 C CD . GLU A 1 789 ? 23.448 74.099 -8.234 1.00 10.16 ? 789 GLU A CD 1 ATOM 6367 O OE1 . GLU A 1 789 ? 24.275 73.267 -8.707 1.00 11.04 ? 789 GLU A OE1 1 ATOM 6368 O OE2 . GLU A 1 789 ? 22.832 73.963 -7.168 1.00 10.24 ? 789 GLU A OE2 1 ATOM 6369 N N . ILE A 1 790 ? 25.156 76.948 -13.174 1.00 9.13 ? 790 ILE A N 1 ATOM 6370 C CA . ILE A 1 790 ? 25.258 76.992 -14.616 1.00 10.93 ? 790 ILE A CA 1 ATOM 6371 C C . ILE A 1 790 ? 25.622 75.612 -15.140 1.00 9.31 ? 790 ILE A C 1 ATOM 6372 O O . ILE A 1 790 ? 26.620 75.028 -14.686 1.00 9.76 ? 790 ILE A O 1 ATOM 6373 C CB . ILE A 1 790 ? 26.358 78.007 -15.053 1.00 10.61 ? 790 ILE A CB 1 ATOM 6374 C CG1 . ILE A 1 790 ? 26.029 79.445 -14.601 1.00 14.53 ? 790 ILE A CG1 1 ATOM 6375 C CG2 . ILE A 1 790 ? 26.566 77.946 -16.568 1.00 11.96 ? 790 ILE A CG2 1 ATOM 6376 C CD1 . ILE A 1 790 ? 27.234 80.399 -14.707 1.00 17.17 ? 790 ILE A CD1 1 ATOM 6377 N N . VAL A 1 791 ? 24.860 75.114 -16.099 1.00 9.20 ? 791 VAL A N 1 ATOM 6378 C CA . VAL A 1 791 ? 25.044 73.795 -16.673 1.00 9.01 ? 791 VAL A CA 1 ATOM 6379 C C . VAL A 1 791 ? 25.322 73.904 -18.163 1.00 8.96 ? 791 VAL A C 1 ATOM 6380 O O . VAL A 1 791 ? 24.730 74.742 -18.842 1.00 9.22 ? 791 VAL A O 1 ATOM 6381 C CB . VAL A 1 791 ? 23.821 72.870 -16.373 1.00 9.53 ? 791 VAL A CB 1 ATOM 6382 C CG1 . VAL A 1 791 ? 22.550 73.344 -17.095 1.00 12.62 ? 791 VAL A CG1 1 ATOM 6383 C CG2 . VAL A 1 791 ? 24.147 71.411 -16.711 1.00 11.68 ? 791 VAL A CG2 1 ATOM 6384 N N . MET A 1 792 ? 26.220 73.070 -18.657 1.00 8.52 ? 792 MET A N 1 ATOM 6385 C CA . MET A 1 792 ? 26.467 72.944 -20.080 1.00 8.72 ? 792 MET A CA 1 ATOM 6386 C C . MET A 1 792 ? 25.802 71.658 -20.544 1.00 8.68 ? 792 MET A C 1 ATOM 6387 O O . MET A 1 792 ? 26.139 70.572 -20.043 1.00 9.42 ? 792 MET A O 1 ATOM 6388 C CB . MET A 1 792 ? 27.973 72.898 -20.423 1.00 9.13 ? 792 MET A CB 1 ATOM 6389 C CG . MET A 1 792 ? 28.263 72.739 -21.898 1.00 11.19 ? 792 MET A CG 1 ATOM 6390 S SD . MET A 1 792 ? 30.025 72.836 -22.255 1.00 10.80 ? 792 MET A SD 1 ATOM 6391 C CE . MET A 1 792 ? 30.610 71.327 -21.477 1.00 13.02 ? 792 MET A CE 1 ATOM 6392 N N . ARG A 1 793 ? 24.875 71.751 -21.491 1.00 8.81 ? 793 ARG A N 1 ATOM 6393 C CA . ARG A 1 793 ? 24.160 70.587 -21.994 1.00 9.08 ? 793 ARG A CA 1 ATOM 6394 C C . ARG A 1 793 ? 24.485 70.374 -23.447 1.00 9.49 ? 793 ARG A C 1 ATOM 6395 O O . ARG A 1 793 ? 24.650 71.337 -24.228 1.00 10.14 ? 793 ARG A O 1 ATOM 6396 C CB . ARG A 1 793 ? 22.663 70.806 -21.811 1.00 9.79 ? 793 ARG A CB 1 ATOM 6397 C CG . ARG A 1 793 ? 21.805 69.604 -22.254 1.00 10.13 ? 793 ARG A CG 1 ATOM 6398 C CD . ARG A 1 793 ? 20.305 69.792 -21.957 1.00 10.84 ? 793 ARG A CD 1 ATOM 6399 N NE . ARG A 1 793 ? 20.068 69.873 -20.522 1.00 11.72 ? 793 ARG A NE 1 ATOM 6400 C CZ . ARG A 1 793 ? 18.999 70.436 -19.951 1.00 12.01 ? 793 ARG A CZ 1 ATOM 6401 N NH1 . ARG A 1 793 ? 18.030 70.984 -20.723 1.00 12.08 ? 793 ARG A NH1 1 ATOM 6402 N NH2 . ARG A 1 793 ? 18.887 70.521 -18.649 1.00 11.70 ? 793 ARG A NH2 1 ATOM 6403 N N . LEU A 1 794 ? 24.577 69.111 -23.829 1.00 9.71 ? 794 LEU A N 1 ATOM 6404 C CA . LEU A 1 794 ? 24.648 68.645 -25.215 1.00 10.41 ? 794 LEU A CA 1 ATOM 6405 C C . LEU A 1 794 ? 23.345 67.947 -25.595 1.00 11.26 ? 794 LEU A C 1 ATOM 6406 O O . LEU A 1 794 ? 22.883 67.071 -24.866 1.00 11.13 ? 794 LEU A O 1 ATOM 6407 C CB . LEU A 1 794 ? 25.787 67.659 -25.397 1.00 11.20 ? 794 LEU A CB 1 ATOM 6408 C CG . LEU A 1 794 ? 27.146 68.309 -25.498 1.00 11.65 ? 794 LEU A CG 1 ATOM 6409 C CD1 . LEU A 1 794 ? 28.262 67.322 -25.109 1.00 14.16 ? 794 LEU A CD1 1 ATOM 6410 C CD2 . LEU A 1 794 ? 27.342 68.741 -26.941 1.00 16.73 ? 794 LEU A CD2 1 ATOM 6411 N N . GLU A 1 795 ? 22.726 68.361 -26.708 1.00 11.43 ? 795 GLU A N 1 ATOM 6412 C CA . GLU A 1 795 ? 21.473 67.742 -27.195 1.00 13.49 ? 795 GLU A CA 1 ATOM 6413 C C . GLU A 1 795 ? 21.779 67.050 -28.493 1.00 13.44 ? 795 GLU A C 1 ATOM 6414 O O . GLU A 1 795 ? 22.326 67.641 -29.406 1.00 13.99 ? 795 GLU A O 1 ATOM 6415 C CB . GLU A 1 795 ? 20.373 68.803 -27.402 1.00 14.40 ? 795 GLU A CB 1 ATOM 6416 C CG . GLU A 1 795 ? 20.014 69.573 -26.141 1.00 17.34 ? 795 GLU A CG 1 ATOM 6417 C CD . GLU A 1 795 ? 19.112 70.792 -26.375 1.00 18.12 ? 795 GLU A CD 1 ATOM 6418 O OE1 . GLU A 1 795 ? 19.135 71.358 -27.490 1.00 24.11 ? 795 GLU A OE1 1 ATOM 6419 O OE2 . GLU A 1 795 ? 18.413 71.224 -25.428 1.00 22.57 ? 795 GLU A OE2 1 ATOM 6420 N N . THR A 1 796 ? 21.433 65.764 -28.591 1.00 12.34 ? 796 THR A N 1 ATOM 6421 C CA . THR A 1 796 ? 21.646 64.991 -29.789 1.00 13.05 ? 796 THR A CA 1 ATOM 6422 C C . THR A 1 796 ? 20.395 64.163 -30.131 1.00 12.52 ? 796 THR A C 1 ATOM 6423 O O . THR A 1 796 ? 19.443 64.168 -29.368 1.00 15.14 ? 796 THR A O 1 ATOM 6424 C CB . THR A 1 796 ? 22.837 64.001 -29.667 1.00 12.54 ? 796 THR A CB 1 ATOM 6425 O OG1 . THR A 1 796 ? 22.435 62.841 -28.896 1.00 11.72 ? 796 THR A OG1 1 ATOM 6426 C CG2 . THR A 1 796 ? 24.039 64.607 -28.913 1.00 13.87 ? 796 THR A CG2 1 ATOM 6427 N N A HIS A 1 797 ? 20.532 63.427 -31.225 0.50 13.19 ? 797 HIS A N 1 ATOM 6428 N N B HIS A 1 797 ? 20.419 63.452 -31.247 0.50 13.53 ? 797 HIS A N 1 ATOM 6429 C CA A HIS A 1 797 ? 19.499 62.502 -31.671 0.50 13.53 ? 797 HIS A CA 1 ATOM 6430 C CA B HIS A 1 797 ? 19.321 62.494 -31.512 0.50 13.66 ? 797 HIS A CA 1 ATOM 6431 C C A HIS A 1 797 ? 19.619 61.117 -31.120 0.50 13.59 ? 797 HIS A C 1 ATOM 6432 C C B HIS A 1 797 ? 19.857 61.023 -31.432 0.50 13.80 ? 797 HIS A C 1 ATOM 6433 O O A HIS A 1 797 ? 18.661 60.338 -31.278 0.50 12.14 ? 797 HIS A O 1 ATOM 6434 O O B HIS A 1 797 ? 19.426 60.083 -32.129 0.50 12.66 ? 797 HIS A O 1 ATOM 6435 C CB A HIS A 1 797 ? 19.420 62.475 -33.196 0.50 13.54 ? 797 HIS A CB 1 ATOM 6436 C CB B HIS A 1 797 ? 18.542 62.822 -32.821 0.50 13.10 ? 797 HIS A CB 1 ATOM 6437 C CG A HIS A 1 797 ? 18.727 63.675 -33.749 0.50 11.55 ? 797 HIS A CG 1 ATOM 6438 C CG B HIS A 1 797 ? 18.059 64.245 -32.956 0.50 14.43 ? 797 HIS A CG 1 ATOM 6439 N ND1 A HIS A 1 797 ? 17.990 64.531 -32.951 0.50 13.25 ? 797 HIS A ND1 1 ATOM 6440 N ND1 B HIS A 1 797 ? 17.728 65.045 -31.884 0.50 14.36 ? 797 HIS A ND1 1 ATOM 6441 C CD2 A HIS A 1 797 ? 18.666 64.177 -35.004 0.50 10.86 ? 797 HIS A CD2 1 ATOM 6442 C CD2 B HIS A 1 797 ? 17.818 64.994 -34.067 0.50 11.17 ? 797 HIS A CD2 1 ATOM 6443 C CE1 A HIS A 1 797 ? 17.494 65.497 -33.705 0.50 10.14 ? 797 HIS A CE1 1 ATOM 6444 C CE1 B HIS A 1 797 ? 17.331 66.230 -32.322 0.50 15.42 ? 797 HIS A CE1 1 ATOM 6445 N NE2 A HIS A 1 797 ? 17.903 65.315 -34.944 0.50 13.61 ? 797 HIS A NE2 1 ATOM 6446 N NE2 B HIS A 1 797 ? 17.374 66.222 -33.641 0.50 16.38 ? 797 HIS A NE2 1 ATOM 6447 N N . ILE A 1 798 ? 20.789 60.826 -30.502 1.00 13.32 ? 798 ILE A N 1 ATOM 6448 C CA . ILE A 1 798 ? 21.212 59.479 -30.121 1.00 13.04 ? 798 ILE A CA 1 ATOM 6449 C C . ILE A 1 798 ? 20.115 58.888 -29.269 1.00 12.79 ? 798 ILE A C 1 ATOM 6450 O O . ILE A 1 798 ? 19.606 59.506 -28.362 1.00 13.03 ? 798 ILE A O 1 ATOM 6451 C CB . ILE A 1 798 ? 22.546 59.531 -29.368 1.00 12.02 ? 798 ILE A CB 1 ATOM 6452 C CG1 . ILE A 1 798 ? 23.639 59.991 -30.307 1.00 13.46 ? 798 ILE A CG1 1 ATOM 6453 C CG2 . ILE A 1 798 ? 22.889 58.120 -28.778 1.00 14.16 ? 798 ILE A CG2 1 ATOM 6454 C CD1 . ILE A 1 798 ? 24.964 60.330 -29.570 1.00 13.29 ? 798 ILE A CD1 1 ATOM 6455 N N . ASP A 1 799 ? 19.715 57.665 -29.649 1.00 14.27 ? 799 ASP A N 1 ATOM 6456 C CA . ASP A 1 799 ? 18.606 56.995 -28.998 1.00 13.94 ? 799 ASP A CA 1 ATOM 6457 C C . ASP A 1 799 ? 19.036 56.242 -27.730 1.00 13.37 ? 799 ASP A C 1 ATOM 6458 O O . ASP A 1 799 ? 19.001 55.011 -27.670 1.00 12.50 ? 799 ASP A O 1 ATOM 6459 C CB . ASP A 1 799 ? 17.921 56.039 -30.012 1.00 16.02 ? 799 ASP A CB 1 ATOM 6460 C CG . ASP A 1 799 ? 16.607 55.504 -29.512 1.00 18.51 ? 799 ASP A CG 1 ATOM 6461 O OD1 . ASP A 1 799 ? 15.990 56.105 -28.635 1.00 23.52 ? 799 ASP A OD1 1 ATOM 6462 O OD2 . ASP A 1 799 ? 16.113 54.451 -29.938 1.00 24.54 ? 799 ASP A OD2 1 ATOM 6463 N N . SER A 1 800 ? 19.497 57.002 -26.735 1.00 12.90 ? 800 SER A N 1 ATOM 6464 C CA . SER A 1 800 ? 20.077 56.426 -25.520 1.00 12.13 ? 800 SER A CA 1 ATOM 6465 C C . SER A 1 800 ? 19.016 56.027 -24.516 1.00 11.83 ? 800 SER A C 1 ATOM 6466 O O . SER A 1 800 ? 19.293 55.240 -23.594 1.00 12.01 ? 800 SER A O 1 ATOM 6467 C CB . SER A 1 800 ? 21.078 57.429 -24.895 1.00 11.40 ? 800 SER A CB 1 ATOM 6468 O OG . SER A 1 800 ? 20.438 58.646 -24.561 1.00 11.59 ? 800 SER A OG 1 ATOM 6469 N N . GLY A 1 801 ? 17.792 56.552 -24.629 1.00 12.02 ? 801 GLY A N 1 ATOM 6470 C CA . GLY A 1 801 ? 16.748 56.178 -23.712 1.00 13.03 ? 801 GLY A CA 1 ATOM 6471 C C . GLY A 1 801 ? 17.018 56.705 -22.340 1.00 13.13 ? 801 GLY A C 1 ATOM 6472 O O . GLY A 1 801 ? 17.067 57.924 -22.169 1.00 14.08 ? 801 GLY A O 1 ATOM 6473 N N . ASP A 1 802 ? 17.126 55.804 -21.367 1.00 12.24 ? 802 ASP A N 1 ATOM 6474 C CA . ASP A 1 802 ? 17.413 56.197 -19.996 1.00 12.57 ? 802 ASP A CA 1 ATOM 6475 C C . ASP A 1 802 ? 18.813 55.767 -19.540 1.00 11.65 ? 802 ASP A C 1 ATOM 6476 O O . ASP A 1 802 ? 19.091 55.841 -18.335 1.00 11.92 ? 802 ASP A O 1 ATOM 6477 C CB . ASP A 1 802 ? 16.336 55.662 -19.034 1.00 13.45 ? 802 ASP A CB 1 ATOM 6478 C CG . ASP A 1 802 ? 16.147 54.162 -19.127 1.00 14.74 ? 802 ASP A CG 1 ATOM 6479 O OD1 . ASP A 1 802 ? 16.942 53.466 -19.776 1.00 16.61 ? 802 ASP A OD1 1 ATOM 6480 O OD2 . ASP A 1 802 ? 15.191 53.613 -18.523 1.00 18.02 ? 802 ASP A OD2 1 ATOM 6481 N N . ILE A 1 803 ? 19.658 55.368 -20.476 1.00 9.89 ? 803 ILE A N 1 ATOM 6482 C CA . ILE A 1 803 ? 20.996 54.875 -20.134 1.00 9.72 ? 803 ILE A CA 1 ATOM 6483 C C . ILE A 1 803 ? 22.054 55.911 -20.452 1.00 9.46 ? 803 ILE A C 1 ATOM 6484 O O . ILE A 1 803 ? 22.025 56.579 -21.494 1.00 8.96 ? 803 ILE A O 1 ATOM 6485 C CB . ILE A 1 803 ? 21.265 53.567 -20.897 1.00 9.92 ? 803 ILE A CB 1 ATOM 6486 C CG1 . ILE A 1 803 ? 20.228 52.479 -20.506 1.00 11.80 ? 803 ILE A CG1 1 ATOM 6487 C CG2 . ILE A 1 803 ? 22.712 53.059 -20.682 1.00 10.71 ? 803 ILE A CG2 1 ATOM 6488 C CD1 . ILE A 1 803 ? 20.198 52.153 -19.031 1.00 15.20 ? 803 ILE A CD1 1 ATOM 6489 N N . PHE A 1 804 ? 23.037 55.997 -19.547 1.00 8.78 ? 804 PHE A N 1 ATOM 6490 C CA . PHE A 1 804 ? 24.247 56.793 -19.793 1.00 8.42 ? 804 PHE A CA 1 ATOM 6491 C C . PHE A 1 804 ? 25.375 56.182 -18.975 1.00 8.06 ? 804 PHE A C 1 ATOM 6492 O O . PHE A 1 804 ? 25.118 55.302 -18.150 1.00 9.51 ? 804 PHE A O 1 ATOM 6493 C CB . PHE A 1 804 ? 24.017 58.290 -19.495 1.00 7.83 ? 804 PHE A CB 1 ATOM 6494 C CG . PHE A 1 804 ? 23.601 58.619 -18.079 1.00 7.39 ? 804 PHE A CG 1 ATOM 6495 C CD1 . PHE A 1 804 ? 22.325 58.418 -17.608 1.00 8.21 ? 804 PHE A CD1 1 ATOM 6496 C CD2 . PHE A 1 804 ? 24.527 59.249 -17.219 1.00 7.75 ? 804 PHE A CD2 1 ATOM 6497 C CE1 . PHE A 1 804 ? 21.957 58.771 -16.356 1.00 8.68 ? 804 PHE A CE1 1 ATOM 6498 C CE2 . PHE A 1 804 ? 24.175 59.625 -15.991 1.00 8.30 ? 804 PHE A CE2 1 ATOM 6499 C CZ . PHE A 1 804 ? 22.900 59.397 -15.507 1.00 8.66 ? 804 PHE A CZ 1 ATOM 6500 N N . TYR A 1 805 ? 26.593 56.599 -19.251 1.00 7.72 ? 805 TYR A N 1 ATOM 6501 C CA . TYR A 1 805 ? 27.755 56.033 -18.565 1.00 7.51 ? 805 TYR A CA 1 ATOM 6502 C C . TYR A 1 805 ? 28.578 57.169 -18.000 1.00 8.03 ? 805 TYR A C 1 ATOM 6503 O O . TYR A 1 805 ? 28.754 58.206 -18.657 1.00 8.31 ? 805 TYR A O 1 ATOM 6504 C CB . TYR A 1 805 ? 28.619 55.273 -19.542 1.00 8.33 ? 805 TYR A CB 1 ATOM 6505 C CG . TYR A 1 805 ? 27.924 54.042 -20.086 1.00 8.28 ? 805 TYR A CG 1 ATOM 6506 C CD1 . TYR A 1 805 ? 26.959 54.146 -21.107 1.00 10.11 ? 805 TYR A CD1 1 ATOM 6507 C CD2 . TYR A 1 805 ? 28.226 52.788 -19.597 1.00 9.90 ? 805 TYR A CD2 1 ATOM 6508 C CE1 . TYR A 1 805 ? 26.307 52.998 -21.591 1.00 10.87 ? 805 TYR A CE1 1 ATOM 6509 C CE2 . TYR A 1 805 ? 27.572 51.621 -20.095 1.00 10.10 ? 805 TYR A CE2 1 ATOM 6510 C CZ . TYR A 1 805 ? 26.600 51.777 -21.072 1.00 10.82 ? 805 TYR A CZ 1 ATOM 6511 O OH . TYR A 1 805 ? 25.944 50.686 -21.611 1.00 11.96 ? 805 TYR A OH 1 ATOM 6512 N N . THR A 1 806 ? 29.075 56.968 -16.777 1.00 7.73 ? 806 THR A N 1 ATOM 6513 C CA . THR A 1 806 ? 29.966 57.963 -16.143 1.00 6.70 ? 806 THR A CA 1 ATOM 6514 C C . THR A 1 806 ? 31.130 57.200 -15.556 1.00 8.10 ? 806 THR A C 1 ATOM 6515 O O . THR A 1 806 ? 31.052 55.993 -15.301 1.00 8.83 ? 806 THR A O 1 ATOM 6516 C CB . THR A 1 806 ? 29.250 58.754 -15.064 1.00 7.70 ? 806 THR A CB 1 ATOM 6517 O OG1 . THR A 1 806 ? 28.839 57.870 -14.020 1.00 8.03 ? 806 THR A OG1 1 ATOM 6518 C CG2 . THR A 1 806 ? 27.966 59.447 -15.588 1.00 8.12 ? 806 THR A CG2 1 ATOM 6519 N N . ASP A 1 807 ? 32.242 57.870 -15.348 1.00 6.67 ? 807 ASP A N 1 ATOM 6520 C CA . ASP A 1 807 ? 33.380 57.164 -14.749 1.00 8.06 ? 807 ASP A CA 1 ATOM 6521 C C . ASP A 1 807 ? 33.424 57.244 -13.248 1.00 6.86 ? 807 ASP A C 1 ATOM 6522 O O . ASP A 1 807 ? 32.773 58.055 -12.605 1.00 7.05 ? 807 ASP A O 1 ATOM 6523 C CB . ASP A 1 807 ? 34.681 57.575 -15.383 1.00 9.56 ? 807 ASP A CB 1 ATOM 6524 C CG . ASP A 1 807 ? 35.146 58.873 -14.925 1.00 9.72 ? 807 ASP A CG 1 ATOM 6525 O OD1 . ASP A 1 807 ? 34.409 59.897 -15.002 1.00 11.16 ? 807 ASP A OD1 1 ATOM 6526 O OD2 . ASP A 1 807 ? 36.316 58.986 -14.422 1.00 11.58 ? 807 ASP A OD2 1 ATOM 6527 N N . LEU A 1 808 ? 34.186 56.310 -12.699 1.00 6.71 ? 808 LEU A N 1 ATOM 6528 C CA . LEU A 1 808 ? 34.489 56.268 -11.276 1.00 6.51 ? 808 LEU A CA 1 ATOM 6529 C C . LEU A 1 808 ? 35.980 56.484 -11.113 1.00 5.70 ? 808 LEU A C 1 ATOM 6530 O O . LEU A 1 808 ? 36.780 55.686 -11.581 1.00 6.21 ? 808 LEU A O 1 ATOM 6531 C CB . LEU A 1 808 ? 34.074 54.954 -10.657 1.00 7.15 ? 808 LEU A CB 1 ATOM 6532 C CG . LEU A 1 808 ? 32.547 54.808 -10.550 1.00 8.20 ? 808 LEU A CG 1 ATOM 6533 C CD1 . LEU A 1 808 ? 32.183 53.351 -10.341 1.00 10.22 ? 808 LEU A CD1 1 ATOM 6534 C CD2 . LEU A 1 808 ? 31.949 55.653 -9.449 1.00 10.37 ? 808 LEU A CD2 1 ATOM 6535 N N . ASN A 1 809 ? 36.333 57.657 -10.581 1.00 5.76 ? 809 ASN A N 1 ATOM 6536 C CA . ASN A 1 809 ? 37.721 57.977 -10.227 1.00 5.98 ? 809 ASN A CA 1 ATOM 6537 C C . ASN A 1 809 ? 38.691 57.882 -11.381 1.00 6.26 ? 809 ASN A C 1 ATOM 6538 O O . ASN A 1 809 ? 39.892 57.639 -11.192 1.00 6.49 ? 809 ASN A O 1 ATOM 6539 C CB . ASN A 1 809 ? 38.228 57.078 -9.069 1.00 5.51 ? 809 ASN A CB 1 ATOM 6540 C CG . ASN A 1 809 ? 37.209 56.996 -7.962 1.00 6.21 ? 809 ASN A CG 1 ATOM 6541 O OD1 . ASN A 1 809 ? 36.331 56.112 -7.988 1.00 6.72 ? 809 ASN A OD1 1 ATOM 6542 N ND2 . ASN A 1 809 ? 37.212 57.967 -7.050 1.00 7.21 ? 809 ASN A ND2 1 ATOM 6543 N N . GLY A 1 810 ? 38.211 58.084 -12.618 1.00 5.75 ? 810 GLY A N 1 ATOM 6544 C CA . GLY A 1 810 ? 39.125 57.989 -13.760 1.00 7.78 ? 810 GLY A CA 1 ATOM 6545 C C . GLY A 1 810 ? 39.606 56.580 -14.056 1.00 8.54 ? 810 GLY A C 1 ATOM 6546 O O . GLY A 1 810 ? 40.554 56.421 -14.851 1.00 9.42 ? 810 GLY A O 1 ATOM 6547 N N . LEU A 1 811 ? 38.988 55.584 -13.430 1.00 7.21 ? 811 LEU A N 1 ATOM 6548 C CA . LEU A 1 811 ? 39.444 54.211 -13.501 1.00 8.84 ? 811 LEU A CA 1 ATOM 6549 C C . LEU A 1 811 ? 38.543 53.312 -14.368 1.00 9.41 ? 811 LEU A C 1 ATOM 6550 O O . LEU A 1 811 ? 39.047 52.405 -15.024 1.00 10.95 ? 811 LEU A O 1 ATOM 6551 C CB . LEU A 1 811 ? 39.507 53.643 -12.078 1.00 8.67 ? 811 LEU A CB 1 ATOM 6552 C CG . LEU A 1 811 ? 39.936 52.186 -11.917 1.00 10.02 ? 811 LEU A CG 1 ATOM 6553 C CD1 . LEU A 1 811 ? 41.358 51.991 -12.421 1.00 12.24 ? 811 LEU A CD1 1 ATOM 6554 C CD2 . LEU A 1 811 ? 39.801 51.673 -10.458 1.00 10.58 ? 811 LEU A CD2 1 ATOM 6555 N N . GLN A 1 812 ? 37.232 53.521 -14.323 1.00 7.54 ? 812 GLN A N 1 ATOM 6556 C CA . GLN A 1 812 ? 36.269 52.600 -14.951 1.00 7.66 ? 812 GLN A CA 1 ATOM 6557 C C . GLN A 1 812 ? 35.024 53.372 -15.268 1.00 8.01 ? 812 GLN A C 1 ATOM 6558 O O . GLN A 1 812 ? 34.752 54.398 -14.650 1.00 8.85 ? 812 GLN A O 1 ATOM 6559 C CB . GLN A 1 812 ? 35.917 51.466 -13.985 1.00 9.69 ? 812 GLN A CB 1 ATOM 6560 C CG . GLN A 1 812 ? 35.362 51.968 -12.649 1.00 10.96 ? 812 GLN A CG 1 ATOM 6561 C CD . GLN A 1 812 ? 35.082 50.847 -11.698 1.00 12.08 ? 812 GLN A CD 1 ATOM 6562 O OE1 . GLN A 1 812 ? 34.101 50.120 -11.859 1.00 12.50 ? 812 GLN A OE1 1 ATOM 6563 N NE2 . GLN A 1 812 ? 35.902 50.751 -10.656 1.00 13.98 ? 812 GLN A NE2 1 ATOM 6564 N N . PHE A 1 813 ? 34.283 52.918 -16.277 1.00 7.93 ? 813 PHE A N 1 ATOM 6565 C CA . PHE A 1 813 ? 32.982 53.493 -16.619 1.00 8.13 ? 813 PHE A CA 1 ATOM 6566 C C . PHE A 1 813 ? 31.869 52.586 -16.179 1.00 8.07 ? 813 PHE A C 1 ATOM 6567 O O . PHE A 1 813 ? 31.904 51.356 -16.450 1.00 9.86 ? 813 PHE A O 1 ATOM 6568 C CB . PHE A 1 813 ? 32.909 53.793 -18.130 1.00 8.52 ? 813 PHE A CB 1 ATOM 6569 C CG . PHE A 1 813 ? 33.674 55.031 -18.499 1.00 7.82 ? 813 PHE A CG 1 ATOM 6570 C CD1 . PHE A 1 813 ? 35.054 55.001 -18.573 1.00 8.38 ? 813 PHE A CD1 1 ATOM 6571 C CD2 . PHE A 1 813 ? 33.000 56.243 -18.733 1.00 8.74 ? 813 PHE A CD2 1 ATOM 6572 C CE1 . PHE A 1 813 ? 35.766 56.197 -18.847 1.00 10.79 ? 813 PHE A CE1 1 ATOM 6573 C CE2 . PHE A 1 813 ? 33.724 57.416 -19.015 1.00 10.56 ? 813 PHE A CE2 1 ATOM 6574 C CZ . PHE A 1 813 ? 35.086 57.369 -19.074 1.00 10.99 ? 813 PHE A CZ 1 ATOM 6575 N N . ILE A 1 814 ? 30.900 53.151 -15.512 1.00 7.42 ? 814 ILE A N 1 ATOM 6576 C CA . ILE A 1 814 ? 29.813 52.387 -14.954 1.00 8.03 ? 814 ILE A CA 1 ATOM 6577 C C . ILE A 1 814 ? 28.520 52.817 -15.639 1.00 7.65 ? 814 ILE A C 1 ATOM 6578 O O . ILE A 1 814 ? 28.286 54.015 -15.897 1.00 7.71 ? 814 ILE A O 1 ATOM 6579 C CB . ILE A 1 814 ? 29.747 52.577 -13.416 1.00 7.66 ? 814 ILE A CB 1 ATOM 6580 C CG1 . ILE A 1 814 ? 28.658 51.681 -12.775 1.00 8.35 ? 814 ILE A CG1 1 ATOM 6581 C CG2 . ILE A 1 814 ? 29.520 54.026 -13.001 1.00 8.62 ? 814 ILE A CG2 1 ATOM 6582 C CD1 . ILE A 1 814 ? 28.827 51.486 -11.260 1.00 9.37 ? 814 ILE A CD1 1 ATOM 6583 N N . LYS A 1 815 ? 27.659 51.842 -15.942 1.00 7.51 ? 815 LYS A N 1 ATOM 6584 C CA A LYS A 1 815 ? 26.354 52.110 -16.521 0.50 8.16 ? 815 LYS A CA 1 ATOM 6585 C CA B LYS A 1 815 ? 26.345 52.116 -16.512 0.50 8.32 ? 815 LYS A CA 1 ATOM 6586 C C . LYS A 1 815 ? 25.436 52.747 -15.489 1.00 7.80 ? 815 LYS A C 1 ATOM 6587 O O . LYS A 1 815 ? 25.314 52.272 -14.354 1.00 8.33 ? 815 LYS A O 1 ATOM 6588 C CB A LYS A 1 815 ? 25.774 50.785 -17.029 0.50 8.53 ? 815 LYS A CB 1 ATOM 6589 C CB B LYS A 1 815 ? 25.707 50.818 -17.023 0.50 8.73 ? 815 LYS A CB 1 ATOM 6590 C CG A LYS A 1 815 ? 24.635 50.900 -18.028 0.50 9.09 ? 815 LYS A CG 1 ATOM 6591 C CG B LYS A 1 815 ? 24.305 51.015 -17.620 0.50 9.24 ? 815 LYS A CG 1 ATOM 6592 C CD A LYS A 1 815 ? 24.158 49.500 -18.429 0.50 9.17 ? 815 LYS A CD 1 ATOM 6593 C CD B LYS A 1 815 ? 23.656 49.709 -18.113 0.50 9.96 ? 815 LYS A CD 1 ATOM 6594 C CE A LYS A 1 815 ? 23.003 49.546 -19.401 0.50 12.44 ? 815 LYS A CE 1 ATOM 6595 C CE B LYS A 1 815 ? 24.553 48.954 -19.060 0.50 12.80 ? 815 LYS A CE 1 ATOM 6596 N NZ A LYS A 1 815 ? 22.585 48.164 -19.802 0.50 14.13 ? 815 LYS A NZ 1 ATOM 6597 N NZ B LYS A 1 815 ? 23.788 47.770 -19.598 0.50 17.24 ? 815 LYS A NZ 1 ATOM 6598 N N . ARG A 1 816 ? 24.790 53.832 -15.888 1.00 7.90 ? 816 ARG A N 1 ATOM 6599 C CA . ARG A 1 816 ? 23.775 54.525 -15.127 1.00 8.12 ? 816 ARG A CA 1 ATOM 6600 C C . ARG A 1 816 ? 22.433 54.401 -15.828 1.00 8.47 ? 816 ARG A C 1 ATOM 6601 O O . ARG A 1 816 ? 22.370 54.368 -17.059 1.00 8.56 ? 816 ARG A O 1 ATOM 6602 C CB . ARG A 1 816 ? 24.077 56.047 -14.999 1.00 8.52 ? 816 ARG A CB 1 ATOM 6603 C CG . ARG A 1 816 ? 25.471 56.418 -14.474 1.00 8.45 ? 816 ARG A CG 1 ATOM 6604 C CD . ARG A 1 816 ? 25.721 55.799 -13.140 1.00 8.65 ? 816 ARG A CD 1 ATOM 6605 N NE . ARG A 1 816 ? 26.922 56.373 -12.497 1.00 7.71 ? 816 ARG A NE 1 ATOM 6606 C CZ . ARG A 1 816 ? 27.293 55.986 -11.278 1.00 8.60 ? 816 ARG A CZ 1 ATOM 6607 N NH1 . ARG A 1 816 ? 26.595 55.073 -10.625 1.00 7.71 ? 816 ARG A NH1 1 ATOM 6608 N NH2 . ARG A 1 816 ? 28.347 56.556 -10.699 1.00 8.25 ? 816 ARG A NH2 1 ATOM 6609 N N . ARG A 1 817 ? 21.406 54.386 -14.997 1.00 8.31 ? 817 ARG A N 1 ATOM 6610 C CA . ARG A 1 817 ? 20.055 54.434 -15.564 1.00 8.95 ? 817 ARG A CA 1 ATOM 6611 C C . ARG A 1 817 ? 19.323 55.554 -14.899 1.00 9.01 ? 817 ARG A C 1 ATOM 6612 O O . ARG A 1 817 ? 19.186 55.582 -13.678 1.00 9.72 ? 817 ARG A O 1 ATOM 6613 C CB . ARG A 1 817 ? 19.313 53.100 -15.336 1.00 10.19 ? 817 ARG A CB 1 ATOM 6614 C CG . ARG A 1 817 ? 17.859 53.092 -15.810 1.00 11.37 ? 817 ARG A CG 1 ATOM 6615 C CD . ARG A 1 817 ? 17.138 51.723 -15.606 1.00 12.23 ? 817 ARG A CD 1 ATOM 6616 N NE . ARG A 1 817 ? 17.716 50.691 -16.461 1.00 12.77 ? 817 ARG A NE 1 ATOM 6617 C CZ . ARG A 1 817 ? 18.453 49.666 -16.051 1.00 14.18 ? 817 ARG A CZ 1 ATOM 6618 N NH1 . ARG A 1 817 ? 18.772 49.536 -14.760 1.00 14.30 ? 817 ARG A NH1 1 ATOM 6619 N NH2 . ARG A 1 817 ? 18.894 48.775 -16.943 1.00 17.78 ? 817 ARG A NH2 1 ATOM 6620 N N . ARG A 1 818 ? 18.842 56.497 -15.703 1.00 9.78 ? 818 ARG A N 1 ATOM 6621 C CA A ARG A 1 818 ? 18.019 57.589 -15.196 0.50 10.21 ? 818 ARG A CA 1 ATOM 6622 C CA B ARG A 1 818 ? 18.018 57.588 -15.197 0.50 10.74 ? 818 ARG A CA 1 ATOM 6623 C C . ARG A 1 818 ? 16.800 56.883 -14.609 1.00 10.42 ? 818 ARG A C 1 ATOM 6624 O O . ARG A 1 818 ? 16.304 55.907 -15.171 1.00 12.40 ? 818 ARG A O 1 ATOM 6625 C CB A ARG A 1 818 ? 17.724 58.597 -16.308 0.50 10.64 ? 818 ARG A CB 1 ATOM 6626 C CB B ARG A 1 818 ? 17.590 58.511 -16.339 0.50 10.94 ? 818 ARG A CB 1 ATOM 6627 C CG A ARG A 1 818 ? 16.994 59.845 -15.837 0.50 10.76 ? 818 ARG A CG 1 ATOM 6628 C CG B ARG A 1 818 ? 17.057 59.859 -15.882 0.50 11.76 ? 818 ARG A CG 1 ATOM 6629 C CD A ARG A 1 818 ? 16.281 60.536 -16.988 0.50 8.91 ? 818 ARG A CD 1 ATOM 6630 C CD B ARG A 1 818 ? 16.785 60.775 -17.064 0.50 11.24 ? 818 ARG A CD 1 ATOM 6631 N NE A ARG A 1 818 ? 15.010 59.894 -17.308 0.50 10.93 ? 818 ARG A NE 1 ATOM 6632 N NE B ARG A 1 818 ? 16.105 60.078 -18.152 0.50 17.20 ? 818 ARG A NE 1 ATOM 6633 C CZ A ARG A 1 818 ? 14.715 59.370 -18.494 0.50 10.65 ? 818 ARG A CZ 1 ATOM 6634 C CZ B ARG A 1 818 ? 16.681 59.749 -19.303 0.50 15.63 ? 818 ARG A CZ 1 ATOM 6635 N NH1 A ARG A 1 818 ? 15.602 59.410 -19.478 0.50 8.34 ? 818 ARG A NH1 1 ATOM 6636 N NH1 B ARG A 1 818 ? 17.952 60.053 -19.522 0.50 10.17 ? 818 ARG A NH1 1 ATOM 6637 N NH2 A ARG A 1 818 ? 13.532 58.805 -18.696 0.50 11.64 ? 818 ARG A NH2 1 ATOM 6638 N NH2 B ARG A 1 818 ? 15.985 59.115 -20.237 0.50 16.60 ? 818 ARG A NH2 1 ATOM 6639 N N . LEU A 1 819 ? 16.324 57.385 -13.474 1.00 11.22 ? 819 LEU A N 1 ATOM 6640 C CA . LEU A 1 819 ? 15.113 56.842 -12.835 1.00 12.55 ? 819 LEU A CA 1 ATOM 6641 C C . LEU A 1 819 ? 14.145 57.979 -12.568 1.00 12.43 ? 819 LEU A C 1 ATOM 6642 O O . LEU A 1 819 ? 14.382 58.860 -11.760 1.00 12.74 ? 819 LEU A O 1 ATOM 6643 C CB . LEU A 1 819 ? 15.451 56.117 -11.525 1.00 13.29 ? 819 LEU A CB 1 ATOM 6644 C CG . LEU A 1 819 ? 16.367 54.884 -11.649 1.00 13.82 ? 819 LEU A CG 1 ATOM 6645 C CD1 . LEU A 1 819 ? 16.783 54.374 -10.272 1.00 16.26 ? 819 LEU A CD1 1 ATOM 6646 C CD2 . LEU A 1 819 ? 15.743 53.791 -12.491 1.00 15.81 ? 819 LEU A CD2 1 ATOM 6647 N N . ASP A 1 820 ? 13.016 57.943 -13.273 1.00 13.86 ? 820 ASP A N 1 ATOM 6648 C CA . ASP A 1 820 ? 12.039 58.996 -13.069 1.00 15.57 ? 820 ASP A CA 1 ATOM 6649 C C . ASP A 1 820 ? 11.321 58.876 -11.731 1.00 14.60 ? 820 ASP A C 1 ATOM 6650 O O . ASP A 1 820 ? 10.719 59.836 -11.257 1.00 14.90 ? 820 ASP A O 1 ATOM 6651 C CB . ASP A 1 820 ? 11.078 59.060 -14.252 1.00 16.50 ? 820 ASP A CB 1 ATOM 6652 C CG . ASP A 1 820 ? 11.801 59.401 -15.553 1.00 19.99 ? 820 ASP A CG 1 ATOM 6653 O OD1 . ASP A 1 820 ? 12.881 60.065 -15.518 1.00 20.96 ? 820 ASP A OD1 1 ATOM 6654 O OD2 . ASP A 1 820 ? 11.379 59.035 -16.665 1.00 24.41 ? 820 ASP A OD2 1 ATOM 6655 N N . LYS A 1 821 ? 11.455 57.726 -11.055 1.00 13.66 ? 821 LYS A N 1 ATOM 6656 C CA . LYS A 1 821 ? 10.899 57.597 -9.698 1.00 14.61 ? 821 LYS A CA 1 ATOM 6657 C C . LYS A 1 821 ? 11.731 58.357 -8.648 1.00 14.65 ? 821 LYS A C 1 ATOM 6658 O O . LYS A 1 821 ? 11.269 58.567 -7.538 1.00 15.67 ? 821 LYS A O 1 ATOM 6659 C CB . LYS A 1 821 ? 10.763 56.123 -9.299 1.00 14.33 ? 821 LYS A CB 1 ATOM 6660 C CG . LYS A 1 821 ? 12.114 55.425 -9.057 1.00 13.88 ? 821 LYS A CG 1 ATOM 6661 C CD . LYS A 1 821 ? 11.932 53.931 -8.944 1.00 14.07 ? 821 LYS A CD 1 ATOM 6662 C CE . LYS A 1 821 ? 13.268 53.239 -8.896 1.00 14.45 ? 821 LYS A CE 1 ATOM 6663 N NZ . LYS A 1 821 ? 13.203 51.756 -9.026 1.00 14.96 ? 821 LYS A NZ 1 ATOM 6664 N N . LEU A 1 822 ? 12.929 58.830 -9.046 1.00 13.64 ? 822 LEU A N 1 ATOM 6665 C CA . LEU A 1 822 ? 13.783 59.647 -8.159 1.00 13.47 ? 822 LEU A CA 1 ATOM 6666 C C . LEU A 1 822 ? 13.803 61.076 -8.679 1.00 12.89 ? 822 LEU A C 1 ATOM 6667 O O . LEU A 1 822 ? 13.649 61.275 -9.874 1.00 12.70 ? 822 LEU A O 1 ATOM 6668 C CB . LEU A 1 822 ? 15.209 59.110 -8.171 1.00 13.66 ? 822 LEU A CB 1 ATOM 6669 C CG . LEU A 1 822 ? 15.375 57.668 -7.695 1.00 15.01 ? 822 LEU A CG 1 ATOM 6670 C CD1 . LEU A 1 822 ? 16.856 57.309 -7.638 1.00 16.21 ? 822 LEU A CD1 1 ATOM 6671 C CD2 . LEU A 1 822 ? 14.711 57.413 -6.359 1.00 16.43 ? 822 LEU A CD2 1 ATOM 6672 N N . PRO A 1 823 ? 14.029 62.045 -7.790 1.00 12.49 ? 823 PRO A N 1 ATOM 6673 C CA . PRO A 1 823 ? 14.080 63.455 -8.224 1.00 12.16 ? 823 PRO A CA 1 ATOM 6674 C C . PRO A 1 823 ? 15.323 63.745 -9.072 1.00 12.09 ? 823 PRO A C 1 ATOM 6675 O O . PRO A 1 823 ? 16.304 62.969 -9.099 1.00 11.88 ? 823 PRO A O 1 ATOM 6676 C CB . PRO A 1 823 ? 14.085 64.239 -6.926 1.00 13.68 ? 823 PRO A CB 1 ATOM 6677 C CG . PRO A 1 823 ? 14.674 63.303 -5.910 1.00 13.79 ? 823 PRO A CG 1 ATOM 6678 C CD . PRO A 1 823 ? 14.209 61.913 -6.330 1.00 12.66 ? 823 PRO A CD 1 ATOM 6679 N N . LEU A 1 824 ? 15.273 64.864 -9.786 1.00 11.51 ? 824 LEU A N 1 ATOM 6680 C CA . LEU A 1 824 ? 16.324 65.274 -10.684 1.00 11.40 ? 824 LEU A CA 1 ATOM 6681 C C . LEU A 1 824 ? 17.739 65.123 -10.065 1.00 9.93 ? 824 LEU A C 1 ATOM 6682 O O . LEU A 1 824 ? 18.622 64.557 -10.724 1.00 10.07 ? 824 LEU A O 1 ATOM 6683 C CB . LEU A 1 824 ? 16.041 66.727 -11.099 1.00 11.71 ? 824 LEU A CB 1 ATOM 6684 C CG . LEU A 1 824 ? 16.839 67.306 -12.256 1.00 11.33 ? 824 LEU A CG 1 ATOM 6685 C CD1 . LEU A 1 824 ? 16.063 68.516 -12.822 1.00 12.93 ? 824 LEU A CD1 1 ATOM 6686 C CD2 . LEU A 1 824 ? 18.285 67.724 -11.871 1.00 10.89 ? 824 LEU A CD2 1 ATOM 6687 N N . GLN A 1 825 ? 17.909 65.620 -8.853 1.00 9.85 ? 825 GLN A N 1 ATOM 6688 C CA . GLN A 1 825 ? 19.233 65.666 -8.216 1.00 9.72 ? 825 GLN A CA 1 ATOM 6689 C C . GLN A 1 825 ? 19.772 64.281 -7.895 1.00 10.31 ? 825 GLN A C 1 ATOM 6690 O O . GLN A 1 825 ? 21.012 64.123 -7.724 1.00 9.87 ? 825 GLN A O 1 ATOM 6691 C CB . GLN A 1 825 ? 19.203 66.543 -6.988 1.00 10.50 ? 825 GLN A CB 1 ATOM 6692 C CG . GLN A 1 825 ? 18.281 66.026 -5.874 1.00 10.52 ? 825 GLN A CG 1 ATOM 6693 C CD . GLN A 1 825 ? 16.828 66.518 -5.967 1.00 11.02 ? 825 GLN A CD 1 ATOM 6694 O OE1 . GLN A 1 825 ? 16.376 66.967 -7.027 1.00 11.24 ? 825 GLN A OE1 1 ATOM 6695 N NE2 . GLN A 1 825 ? 16.121 66.442 -4.853 1.00 11.36 ? 825 GLN A NE2 1 ATOM 6696 N N . ALA A 1 826 ? 18.889 63.263 -7.821 1.00 9.17 ? 826 ALA A N 1 ATOM 6697 C CA . ALA A 1 826 ? 19.326 61.894 -7.604 1.00 9.21 ? 826 ALA A CA 1 ATOM 6698 C C . ALA A 1 826 ? 19.934 61.296 -8.847 1.00 9.89 ? 826 ALA A C 1 ATOM 6699 O O . ALA A 1 826 ? 20.666 60.304 -8.781 1.00 10.26 ? 826 ALA A O 1 ATOM 6700 C CB . ALA A 1 826 ? 18.126 61.033 -7.127 1.00 10.41 ? 826 ALA A CB 1 ATOM 6701 N N . ASN A 1 827 ? 19.573 61.844 -10.008 1.00 9.42 ? 827 ASN A N 1 ATOM 6702 C CA . ASN A 1 827 ? 20.068 61.389 -11.307 1.00 9.32 ? 827 ASN A CA 1 ATOM 6703 C C . ASN A 1 827 ? 21.395 62.018 -11.753 1.00 8.15 ? 827 ASN A C 1 ATOM 6704 O O . ASN A 1 827 ? 21.890 61.710 -12.788 1.00 9.04 ? 827 ASN A O 1 ATOM 6705 C CB . ASN A 1 827 ? 18.952 61.534 -12.356 1.00 9.50 ? 827 ASN A CB 1 ATOM 6706 C CG . ASN A 1 827 ? 17.824 60.515 -12.115 1.00 12.39 ? 827 ASN A CG 1 ATOM 6707 O OD1 . ASN A 1 827 ? 18.046 59.326 -12.160 1.00 12.12 ? 827 ASN A OD1 1 ATOM 6708 N ND2 . ASN A 1 827 ? 16.636 61.006 -11.786 1.00 14.50 ? 827 ASN A ND2 1 ATOM 6709 N N . TYR A 1 828 ? 21.905 62.901 -10.898 1.00 8.22 ? 828 TYR A N 1 ATOM 6710 C CA . TYR A 1 828 ? 23.238 63.486 -11.056 1.00 8.00 ? 828 TYR A CA 1 ATOM 6711 C C . TYR A 1 828 ? 24.258 62.544 -10.410 1.00 8.16 ? 828 TYR A C 1 ATOM 6712 O O . TYR A 1 828 ? 24.017 62.010 -9.311 1.00 8.51 ? 828 TYR A O 1 ATOM 6713 C CB . TYR A 1 828 ? 23.298 64.859 -10.350 1.00 9.21 ? 828 TYR A CB 1 ATOM 6714 C CG . TYR A 1 828 ? 23.286 65.990 -11.343 1.00 8.12 ? 828 TYR A CG 1 ATOM 6715 C CD1 . TYR A 1 828 ? 22.228 66.192 -12.227 1.00 9.28 ? 828 TYR A CD1 1 ATOM 6716 C CD2 . TYR A 1 828 ? 24.379 66.840 -11.440 1.00 10.00 ? 828 TYR A CD2 1 ATOM 6717 C CE1 . TYR A 1 828 ? 22.277 67.215 -13.186 1.00 10.32 ? 828 TYR A CE1 1 ATOM 6718 C CE2 . TYR A 1 828 ? 24.427 67.838 -12.354 1.00 10.62 ? 828 TYR A CE2 1 ATOM 6719 C CZ . TYR A 1 828 ? 23.401 68.008 -13.250 1.00 8.73 ? 828 TYR A CZ 1 ATOM 6720 O OH . TYR A 1 828 ? 23.530 69.041 -14.136 1.00 10.40 ? 828 TYR A OH 1 ATOM 6721 N N . TYR A 1 829 ? 25.393 62.390 -11.100 1.00 7.64 ? 829 TYR A N 1 ATOM 6722 C CA . TYR A 1 829 ? 26.471 61.499 -10.680 1.00 8.32 ? 829 TYR A CA 1 ATOM 6723 C C . TYR A 1 829 ? 27.782 62.252 -10.834 1.00 8.65 ? 829 TYR A C 1 ATOM 6724 O O . TYR A 1 829 ? 27.868 63.225 -11.569 1.00 8.12 ? 829 TYR A O 1 ATOM 6725 C CB . TYR A 1 829 ? 26.509 60.231 -11.543 1.00 7.83 ? 829 TYR A CB 1 ATOM 6726 C CG . TYR A 1 829 ? 25.311 59.335 -11.269 1.00 8.00 ? 829 TYR A CG 1 ATOM 6727 C CD1 . TYR A 1 829 ? 25.337 58.460 -10.194 1.00 8.58 ? 829 TYR A CD1 1 ATOM 6728 C CD2 . TYR A 1 829 ? 24.131 59.396 -12.054 1.00 9.03 ? 829 TYR A CD2 1 ATOM 6729 C CE1 . TYR A 1 829 ? 24.236 57.638 -9.891 1.00 8.60 ? 829 TYR A CE1 1 ATOM 6730 C CE2 . TYR A 1 829 ? 23.045 58.586 -11.748 1.00 9.43 ? 829 TYR A CE2 1 ATOM 6731 C CZ . TYR A 1 829 ? 23.118 57.709 -10.692 1.00 8.81 ? 829 TYR A CZ 1 ATOM 6732 O OH . TYR A 1 829 ? 22.072 56.885 -10.335 1.00 10.00 ? 829 TYR A OH 1 ATOM 6733 N N . PRO A 1 830 ? 28.830 61.773 -10.157 1.00 7.88 ? 830 PRO A N 1 ATOM 6734 C CA . PRO A 1 830 ? 30.143 62.381 -10.364 1.00 7.82 ? 830 PRO A CA 1 ATOM 6735 C C . PRO A 1 830 ? 30.596 62.137 -11.801 1.00 7.99 ? 830 PRO A C 1 ATOM 6736 O O . PRO A 1 830 ? 30.365 61.053 -12.350 1.00 8.15 ? 830 PRO A O 1 ATOM 6737 C CB . PRO A 1 830 ? 31.049 61.626 -9.354 1.00 10.96 ? 830 PRO A CB 1 ATOM 6738 C CG . PRO A 1 830 ? 30.170 60.788 -8.512 1.00 9.52 ? 830 PRO A CG 1 ATOM 6739 C CD . PRO A 1 830 ? 28.856 60.610 -9.239 1.00 7.73 ? 830 PRO A CD 1 ATOM 6740 N N . ILE A 1 831 ? 31.226 63.137 -12.423 1.00 6.96 ? 831 ILE A N 1 ATOM 6741 C CA . ILE A 1 831 ? 31.898 62.987 -13.709 1.00 7.56 ? 831 ILE A CA 1 ATOM 6742 C C . ILE A 1 831 ? 33.355 63.292 -13.463 1.00 7.97 ? 831 ILE A C 1 ATOM 6743 O O . ILE A 1 831 ? 33.836 64.386 -13.787 1.00 7.91 ? 831 ILE A O 1 ATOM 6744 C CB . ILE A 1 831 ? 31.307 63.926 -14.808 1.00 6.96 ? 831 ILE A CB 1 ATOM 6745 C CG1 . ILE A 1 831 ? 29.786 63.995 -14.747 1.00 8.19 ? 831 ILE A CG1 1 ATOM 6746 C CG2 . ILE A 1 831 ? 31.851 63.523 -16.152 1.00 8.44 ? 831 ILE A CG2 1 ATOM 6747 C CD1 . ILE A 1 831 ? 29.036 62.680 -15.009 1.00 8.68 ? 831 ILE A CD1 1 ATOM 6748 N N . PRO A 1 832 ? 34.076 62.366 -12.859 1.00 7.04 ? 832 PRO A N 1 ATOM 6749 C CA . PRO A 1 832 ? 35.470 62.671 -12.508 1.00 7.74 ? 832 PRO A CA 1 ATOM 6750 C C . PRO A 1 832 ? 36.357 62.749 -13.716 1.00 8.52 ? 832 PRO A C 1 ATOM 6751 O O . PRO A 1 832 ? 37.325 63.515 -13.593 1.00 11.02 ? 832 PRO A O 1 ATOM 6752 C CB . PRO A 1 832 ? 35.881 61.555 -11.527 1.00 7.73 ? 832 PRO A CB 1 ATOM 6753 C CG . PRO A 1 832 ? 34.849 60.485 -11.719 1.00 8.54 ? 832 PRO A CG 1 ATOM 6754 C CD . PRO A 1 832 ? 33.597 61.112 -12.245 1.00 7.95 ? 832 PRO A CD 1 ATOM 6755 N N . SER A 1 833 ? 36.035 62.124 -14.851 1.00 7.24 ? 833 SER A N 1 ATOM 6756 C CA . SER A 1 833 ? 36.855 62.242 -16.041 1.00 7.54 ? 833 SER A CA 1 ATOM 6757 C C . SER A 1 833 ? 36.107 62.076 -17.386 1.00 6.84 ? 833 SER A C 1 ATOM 6758 O O . SER A 1 833 ? 36.654 62.366 -18.438 1.00 6.80 ? 833 SER A O 1 ATOM 6759 C CB . SER A 1 833 ? 38.071 61.350 -15.995 1.00 10.41 ? 833 SER A CB 1 ATOM 6760 O OG . SER A 1 833 ? 37.768 60.055 -16.295 1.00 11.41 ? 833 SER A OG 1 ATOM 6761 N N . GLY A 1 834 ? 34.892 61.547 -17.333 1.00 7.09 ? 834 GLY A N 1 ATOM 6762 C CA . GLY A 1 834 ? 34.142 61.474 -18.589 1.00 7.31 ? 834 GLY A CA 1 ATOM 6763 C C . GLY A 1 834 ? 32.799 60.818 -18.446 1.00 6.76 ? 834 GLY A C 1 ATOM 6764 O O . GLY A 1 834 ? 32.416 60.224 -17.419 1.00 7.02 ? 834 GLY A O 1 ATOM 6765 N N . MET A 1 835 ? 32.029 60.947 -19.514 1.00 6.90 ? 835 MET A N 1 ATOM 6766 C CA . MET A 1 835 ? 30.683 60.408 -19.562 1.00 7.59 ? 835 MET A CA 1 ATOM 6767 C C . MET A 1 835 ? 30.322 60.189 -21.018 1.00 7.42 ? 835 MET A C 1 ATOM 6768 O O . MET A 1 835 ? 30.872 60.841 -21.888 1.00 7.83 ? 835 MET A O 1 ATOM 6769 C CB . MET A 1 835 ? 29.697 61.383 -18.920 1.00 7.51 ? 835 MET A CB 1 ATOM 6770 C CG . MET A 1 835 ? 29.526 62.682 -19.710 1.00 9.87 ? 835 MET A CG 1 ATOM 6771 S SD . MET A 1 835 ? 28.656 63.998 -18.828 1.00 12.01 ? 835 MET A SD 1 ATOM 6772 C CE . MET A 1 835 ? 27.160 63.154 -18.376 1.00 13.82 ? 835 MET A CE 1 ATOM 6773 N N . PHE A 1 836 ? 29.407 59.260 -21.273 1.00 7.75 ? 836 PHE A N 1 ATOM 6774 C CA . PHE A 1 836 ? 28.973 59.005 -22.653 1.00 8.33 ? 836 PHE A CA 1 ATOM 6775 C C . PHE A 1 836 ? 27.553 58.497 -22.723 1.00 8.66 ? 836 PHE A C 1 ATOM 6776 O O . PHE A 1 836 ? 26.992 57.975 -21.761 1.00 7.84 ? 836 PHE A O 1 ATOM 6777 C CB . PHE A 1 836 ? 29.970 58.179 -23.479 1.00 9.13 ? 836 PHE A CB 1 ATOM 6778 C CG . PHE A 1 836 ? 30.158 56.720 -23.057 1.00 8.04 ? 836 PHE A CG 1 ATOM 6779 C CD1 . PHE A 1 836 ? 29.282 55.706 -23.513 1.00 9.22 ? 836 PHE A CD1 1 ATOM 6780 C CD2 . PHE A 1 836 ? 31.251 56.351 -22.240 1.00 9.03 ? 836 PHE A CD2 1 ATOM 6781 C CE1 . PHE A 1 836 ? 29.492 54.361 -23.127 1.00 11.28 ? 836 PHE A CE1 1 ATOM 6782 C CE2 . PHE A 1 836 ? 31.461 55.011 -21.899 1.00 10.59 ? 836 PHE A CE2 1 ATOM 6783 C CZ . PHE A 1 836 ? 30.586 54.018 -22.371 1.00 10.46 ? 836 PHE A CZ 1 ATOM 6784 N N . ILE A 1 837 ? 26.937 58.731 -23.896 1.00 8.28 ? 837 ILE A N 1 ATOM 6785 C CA . ILE A 1 837 ? 25.642 58.119 -24.252 1.00 9.84 ? 837 ILE A CA 1 ATOM 6786 C C . ILE A 1 837 ? 25.844 57.443 -25.585 1.00 9.20 ? 837 ILE A C 1 ATOM 6787 O O . ILE A 1 837 ? 26.693 57.822 -26.379 1.00 9.31 ? 837 ILE A O 1 ATOM 6788 C CB . ILE A 1 837 ? 24.480 59.145 -24.314 1.00 10.13 ? 837 ILE A CB 1 ATOM 6789 C CG1 . ILE A 1 837 ? 24.864 60.354 -25.169 1.00 9.57 ? 837 ILE A CG1 1 ATOM 6790 C CG2 . ILE A 1 837 ? 23.986 59.498 -22.939 1.00 11.69 ? 837 ILE A CG2 1 ATOM 6791 C CD1 . ILE A 1 837 ? 23.695 61.248 -25.599 1.00 11.51 ? 837 ILE A CD1 1 ATOM 6792 N N . GLU A 1 838 ? 25.037 56.398 -25.809 1.00 9.58 ? 838 GLU A N 1 ATOM 6793 C CA . GLU A 1 838 ? 25.144 55.672 -27.072 1.00 10.73 ? 838 GLU A CA 1 ATOM 6794 C C . GLU A 1 838 ? 23.817 54.974 -27.420 1.00 10.16 ? 838 GLU A C 1 ATOM 6795 O O . GLU A 1 838 ? 22.952 54.744 -26.577 1.00 11.62 ? 838 GLU A O 1 ATOM 6796 C CB . GLU A 1 838 ? 26.286 54.656 -27.058 1.00 10.73 ? 838 GLU A CB 1 ATOM 6797 C CG . GLU A 1 838 ? 26.056 53.547 -26.026 1.00 12.70 ? 838 GLU A CG 1 ATOM 6798 C CD . GLU A 1 838 ? 27.149 52.500 -26.015 1.00 13.70 ? 838 GLU A CD 1 ATOM 6799 O OE1 . GLU A 1 838 ? 28.156 52.636 -26.702 1.00 14.93 ? 838 GLU A OE1 1 ATOM 6800 O OE2 . GLU A 1 838 ? 26.983 51.482 -25.300 1.00 15.60 ? 838 GLU A OE2 1 ATOM 6801 N N . ASP A 1 839 ? 23.685 54.697 -28.720 1.00 11.60 ? 839 ASP A N 1 ATOM 6802 C CA . ASP A 1 839 ? 22.653 53.756 -29.188 1.00 11.86 ? 839 ASP A CA 1 ATOM 6803 C C . ASP A 1 839 ? 23.336 52.668 -29.981 1.00 12.53 ? 839 ASP A C 1 ATOM 6804 O O . ASP A 1 839 ? 24.526 52.464 -29.884 1.00 13.63 ? 839 ASP A O 1 ATOM 6805 C CB . ASP A 1 839 ? 21.509 54.461 -29.934 1.00 12.19 ? 839 ASP A CB 1 ATOM 6806 C CG . ASP A 1 839 ? 21.964 55.230 -31.179 1.00 12.29 ? 839 ASP A CG 1 ATOM 6807 O OD1 . ASP A 1 839 ? 22.984 54.881 -31.782 1.00 13.02 ? 839 ASP A OD1 1 ATOM 6808 O OD2 . ASP A 1 839 ? 21.289 56.216 -31.588 1.00 16.45 ? 839 ASP A OD2 1 ATOM 6809 N N . ALA A 1 840 ? 22.570 51.957 -30.817 1.00 13.62 ? 840 ALA A N 1 ATOM 6810 C CA . ALA A 1 840 ? 23.165 50.892 -31.598 1.00 14.91 ? 840 ALA A CA 1 ATOM 6811 C C . ALA A 1 840 ? 24.300 51.362 -32.516 1.00 14.91 ? 840 ALA A C 1 ATOM 6812 O O . ALA A 1 840 ? 25.229 50.633 -32.784 1.00 16.28 ? 840 ALA A O 1 ATOM 6813 C CB . ALA A 1 840 ? 22.080 50.152 -32.421 1.00 16.69 ? 840 ALA A CB 1 ATOM 6814 N N . ASN A 1 841 ? 24.191 52.593 -33.030 1.00 13.58 ? 841 ASN A N 1 ATOM 6815 C CA . ASN A 1 841 ? 25.105 53.081 -34.074 1.00 13.17 ? 841 ASN A CA 1 ATOM 6816 C C . ASN A 1 841 ? 26.113 54.182 -33.710 1.00 11.28 ? 841 ASN A C 1 ATOM 6817 O O . ASN A 1 841 ? 27.142 54.269 -34.333 1.00 12.69 ? 841 ASN A O 1 ATOM 6818 C CB . ASN A 1 841 ? 24.278 53.554 -35.296 1.00 13.76 ? 841 ASN A CB 1 ATOM 6819 C CG . ASN A 1 841 ? 23.534 52.394 -35.967 1.00 16.06 ? 841 ASN A CG 1 ATOM 6820 O OD1 . ASN A 1 841 ? 24.069 51.304 -36.073 1.00 18.48 ? 841 ASN A OD1 1 ATOM 6821 N ND2 . ASN A 1 841 ? 22.307 52.633 -36.365 1.00 20.00 ? 841 ASN A ND2 1 ATOM 6822 N N . THR A 1 842 ? 25.732 54.995 -32.721 1.00 11.39 ? 842 THR A N 1 ATOM 6823 C CA . THR A 1 842 ? 26.409 56.269 -32.460 1.00 10.96 ? 842 THR A CA 1 ATOM 6824 C C . THR A 1 842 ? 26.683 56.403 -30.968 1.00 10.85 ? 842 THR A C 1 ATOM 6825 O O . THR A 1 842 ? 25.836 56.116 -30.160 1.00 11.43 ? 842 THR A O 1 ATOM 6826 C CB . THR A 1 842 ? 25.502 57.437 -32.891 1.00 11.02 ? 842 THR A CB 1 ATOM 6827 O OG1 . THR A 1 842 ? 25.096 57.267 -34.264 1.00 13.78 ? 842 THR A OG1 1 ATOM 6828 C CG2 . THR A 1 842 ? 26.285 58.780 -32.913 1.00 12.80 ? 842 THR A CG2 1 ATOM 6829 N N . ARG A 1 843 ? 27.854 56.962 -30.677 1.00 10.82 ? 843 ARG A N 1 ATOM 6830 C CA . ARG A 1 843 ? 28.205 57.316 -29.286 1.00 10.13 ? 843 ARG A CA 1 ATOM 6831 C C . ARG A 1 843 ? 28.734 58.759 -29.261 1.00 9.82 ? 843 ARG A C 1 ATOM 6832 O O . ARG A 1 843 ? 29.468 59.165 -30.170 1.00 9.93 ? 843 ARG A O 1 ATOM 6833 C CB . ARG A 1 843 ? 29.290 56.375 -28.755 1.00 10.90 ? 843 ARG A CB 1 ATOM 6834 C CG . ARG A 1 843 ? 29.713 56.650 -27.287 1.00 9.81 ? 843 ARG A CG 1 ATOM 6835 C CD . ARG A 1 843 ? 30.882 55.812 -26.860 1.00 10.04 ? 843 ARG A CD 1 ATOM 6836 N NE . ARG A 1 843 ? 30.487 54.417 -26.580 1.00 10.73 ? 843 ARG A NE 1 ATOM 6837 C CZ . ARG A 1 843 ? 31.303 53.573 -25.980 1.00 11.37 ? 843 ARG A CZ 1 ATOM 6838 N NH1 . ARG A 1 843 ? 32.537 53.941 -25.655 1.00 10.15 ? 843 ARG A NH1 1 ATOM 6839 N NH2 . ARG A 1 843 ? 30.869 52.348 -25.702 1.00 11.87 ? 843 ARG A NH2 1 ATOM 6840 N N . LEU A 1 844 ? 28.357 59.471 -28.209 1.00 8.97 ? 844 LEU A N 1 ATOM 6841 C CA . LEU A 1 844 ? 28.963 60.789 -27.921 1.00 8.99 ? 844 LEU A CA 1 ATOM 6842 C C . LEU A 1 844 ? 29.620 60.671 -26.536 1.00 8.59 ? 844 LEU A C 1 ATOM 6843 O O . LEU A 1 844 ? 28.935 60.356 -25.567 1.00 8.52 ? 844 LEU A O 1 ATOM 6844 C CB . LEU A 1 844 ? 27.904 61.885 -27.930 1.00 9.87 ? 844 LEU A CB 1 ATOM 6845 C CG . LEU A 1 844 ? 28.528 63.298 -27.818 1.00 10.44 ? 844 LEU A CG 1 ATOM 6846 C CD1 . LEU A 1 844 ? 29.424 63.621 -28.987 1.00 13.13 ? 844 LEU A CD1 1 ATOM 6847 C CD2 . LEU A 1 844 ? 27.399 64.320 -27.635 1.00 13.25 ? 844 LEU A CD2 1 ATOM 6848 N N . THR A 1 845 ? 30.931 60.941 -26.517 1.00 8.18 ? 845 THR A N 1 ATOM 6849 C CA . THR A 1 845 ? 31.699 60.917 -25.257 1.00 8.65 ? 845 THR A CA 1 ATOM 6850 C C . THR A 1 845 ? 32.221 62.325 -24.962 1.00 8.30 ? 845 THR A C 1 ATOM 6851 O O . THR A 1 845 ? 32.821 62.962 -25.836 1.00 8.53 ? 845 THR A O 1 ATOM 6852 C CB . THR A 1 845 ? 32.896 59.972 -25.378 1.00 8.04 ? 845 THR A CB 1 ATOM 6853 O OG1 . THR A 1 845 ? 32.439 58.644 -25.743 1.00 9.45 ? 845 THR A OG1 1 ATOM 6854 C CG2 . THR A 1 845 ? 33.609 59.755 -24.022 1.00 8.90 ? 845 THR A CG2 1 ATOM 6855 N N . LEU A 1 846 ? 32.026 62.767 -23.730 1.00 7.87 ? 846 LEU A N 1 ATOM 6856 C CA . LEU A 1 846 ? 32.576 64.049 -23.258 1.00 8.31 ? 846 LEU A CA 1 ATOM 6857 C C . LEU A 1 846 ? 33.625 63.724 -22.188 1.00 6.89 ? 846 LEU A C 1 ATOM 6858 O O . LEU A 1 846 ? 33.266 63.130 -21.163 1.00 7.11 ? 846 LEU A O 1 ATOM 6859 C CB . LEU A 1 846 ? 31.471 64.934 -22.689 1.00 8.95 ? 846 LEU A CB 1 ATOM 6860 C CG . LEU A 1 846 ? 31.909 66.310 -22.172 1.00 10.31 ? 846 LEU A CG 1 ATOM 6861 C CD1 . LEU A 1 846 ? 32.377 67.192 -23.335 1.00 10.23 ? 846 LEU A CD1 1 ATOM 6862 C CD2 . LEU A 1 846 ? 30.837 67.019 -21.350 1.00 13.16 ? 846 LEU A CD2 1 ATOM 6863 N N . LEU A 1 847 ? 34.883 64.028 -22.465 1.00 7.34 ? 847 LEU A N 1 ATOM 6864 C CA . LEU A 1 847 ? 35.973 63.825 -21.488 1.00 6.12 ? 847 LEU A CA 1 ATOM 6865 C C . LEU A 1 847 ? 36.220 65.134 -20.770 1.00 6.94 ? 847 LEU A C 1 ATOM 6866 O O . LEU A 1 847 ? 36.112 66.204 -21.402 1.00 7.36 ? 847 LEU A O 1 ATOM 6867 C CB . LEU A 1 847 ? 37.248 63.357 -22.170 1.00 7.30 ? 847 LEU A CB 1 ATOM 6868 C CG . LEU A 1 847 ? 37.241 61.997 -22.887 1.00 7.17 ? 847 LEU A CG 1 ATOM 6869 C CD1 . LEU A 1 847 ? 36.589 60.888 -22.058 1.00 8.62 ? 847 LEU A CD1 1 ATOM 6870 C CD2 . LEU A 1 847 ? 36.593 62.067 -24.270 1.00 9.35 ? 847 LEU A CD2 1 ATOM 6871 N N . THR A 1 848 ? 36.586 65.064 -19.491 1.00 6.57 ? 848 THR A N 1 ATOM 6872 C CA A THR A 1 848 ? 36.814 66.292 -18.692 0.50 6.98 ? 848 THR A CA 1 ATOM 6873 C CA B THR A 1 848 ? 36.775 66.267 -18.675 0.50 7.51 ? 848 THR A CA 1 ATOM 6874 C C . THR A 1 848 ? 38.204 66.376 -18.098 1.00 7.99 ? 848 THR A C 1 ATOM 6875 O O . THR A 1 848 ? 38.879 65.354 -17.808 1.00 8.34 ? 848 THR A O 1 ATOM 6876 C CB A THR A 1 848 ? 35.899 66.416 -17.498 0.50 7.99 ? 848 THR A CB 1 ATOM 6877 C CB B THR A 1 848 ? 35.740 66.259 -17.559 0.50 8.54 ? 848 THR A CB 1 ATOM 6878 O OG1 A THR A 1 848 ? 36.277 65.431 -16.517 0.50 6.69 ? 848 THR A OG1 1 ATOM 6879 O OG1 B THR A 1 848 ? 34.444 65.957 -18.092 0.50 13.70 ? 848 THR A OG1 1 ATOM 6880 C CG2 A THR A 1 848 ? 34.455 66.162 -17.815 0.50 10.34 ? 848 THR A CG2 1 ATOM 6881 C CG2 B THR A 1 848 ? 35.565 67.610 -16.966 0.50 7.92 ? 848 THR A CG2 1 ATOM 6882 N N . GLY A 1 849 ? 38.673 67.612 -17.952 1.00 6.39 ? 849 GLY A N 1 ATOM 6883 C CA . GLY A 1 849 ? 39.928 67.870 -17.276 1.00 6.25 ? 849 GLY A CA 1 ATOM 6884 C C . GLY A 1 849 ? 39.771 68.213 -15.814 1.00 6.04 ? 849 GLY A C 1 ATOM 6885 O O . GLY A 1 849 ? 40.727 68.638 -15.170 1.00 6.71 ? 849 GLY A O 1 ATOM 6886 N N . GLN A 1 850 ? 38.583 67.996 -15.276 1.00 5.86 ? 850 GLN A N 1 ATOM 6887 C CA . GLN A 1 850 ? 38.264 68.330 -13.904 1.00 5.79 ? 850 GLN A CA 1 ATOM 6888 C C . GLN A 1 850 ? 37.002 67.576 -13.497 1.00 5.70 ? 850 GLN A C 1 ATOM 6889 O O . GLN A 1 850 ? 36.105 67.383 -14.350 1.00 6.98 ? 850 GLN A O 1 ATOM 6890 C CB . GLN A 1 850 ? 38.059 69.858 -13.747 1.00 6.62 ? 850 GLN A CB 1 ATOM 6891 C CG . GLN A 1 850 ? 36.928 70.446 -14.643 1.00 6.83 ? 850 GLN A CG 1 ATOM 6892 C CD . GLN A 1 850 ? 37.277 70.536 -16.114 1.00 6.91 ? 850 GLN A CD 1 ATOM 6893 O OE1 . GLN A 1 850 ? 38.392 70.941 -16.485 1.00 7.57 ? 850 GLN A OE1 1 ATOM 6894 N NE2 . GLN A 1 850 ? 36.309 70.214 -16.984 1.00 6.88 ? 850 GLN A NE2 1 ATOM 6895 N N . PRO A 1 851 ? 36.870 67.157 -12.249 1.00 5.72 ? 851 PRO A N 1 ATOM 6896 C CA . PRO A 1 851 ? 35.627 66.486 -11.827 1.00 5.82 ? 851 PRO A CA 1 ATOM 6897 C C . PRO A 1 851 ? 34.519 67.492 -11.618 1.00 6.63 ? 851 PRO A C 1 ATOM 6898 O O . PRO A 1 851 ? 34.713 68.539 -10.987 1.00 6.97 ? 851 PRO A O 1 ATOM 6899 C CB . PRO A 1 851 ? 36.010 65.837 -10.478 1.00 6.56 ? 851 PRO A CB 1 ATOM 6900 C CG . PRO A 1 851 ? 37.170 66.755 -9.964 1.00 6.59 ? 851 PRO A CG 1 ATOM 6901 C CD . PRO A 1 851 ? 37.891 67.245 -11.183 1.00 5.84 ? 851 PRO A CD 1 ATOM 6902 N N . LEU A 1 852 ? 33.349 67.161 -12.170 1.00 6.41 ? 852 LEU A N 1 ATOM 6903 C CA . LEU A 1 852 ? 32.140 67.987 -12.076 1.00 7.46 ? 852 LEU A CA 1 ATOM 6904 C C . LEU A 1 852 ? 30.926 67.083 -12.016 1.00 8.07 ? 852 LEU A C 1 ATOM 6905 O O . LEU A 1 852 ? 31.050 65.888 -12.294 1.00 11.84 ? 852 LEU A O 1 ATOM 6906 C CB . LEU A 1 852 ? 32.014 68.889 -13.296 1.00 7.85 ? 852 LEU A CB 1 ATOM 6907 C CG . LEU A 1 852 ? 33.147 69.912 -13.472 1.00 6.98 ? 852 LEU A CG 1 ATOM 6908 C CD1 . LEU A 1 852 ? 33.096 70.486 -14.921 1.00 9.42 ? 852 LEU A CD1 1 ATOM 6909 C CD2 . LEU A 1 852 ? 33.085 71.038 -12.492 1.00 8.66 ? 852 LEU A CD2 1 ATOM 6910 N N . GLY A 1 853 ? 29.769 67.590 -11.641 1.00 7.18 ? 853 GLY A N 1 ATOM 6911 C CA . GLY A 1 853 ? 28.557 66.768 -11.608 1.00 7.49 ? 853 GLY A CA 1 ATOM 6912 C C . GLY A 1 853 ? 27.853 66.759 -12.932 1.00 7.23 ? 853 GLY A C 1 ATOM 6913 O O . GLY A 1 853 ? 27.914 67.732 -13.698 1.00 7.29 ? 853 GLY A O 1 ATOM 6914 N N . GLY A 1 854 ? 27.169 65.672 -13.246 1.00 7.12 ? 854 GLY A N 1 ATOM 6915 C CA . GLY A 1 854 ? 26.456 65.642 -14.509 1.00 8.77 ? 854 GLY A CA 1 ATOM 6916 C C . GLY A 1 854 ? 25.461 64.516 -14.609 1.00 7.66 ? 854 GLY A C 1 ATOM 6917 O O . GLY A 1 854 ? 25.278 63.690 -13.694 1.00 7.83 ? 854 GLY A O 1 ATOM 6918 N N . SER A 1 855 ? 24.761 64.494 -15.749 1.00 8.19 ? 855 SER A N 1 ATOM 6919 C CA . SER A 1 855 ? 23.671 63.520 -15.914 1.00 8.83 ? 855 SER A CA 1 ATOM 6920 C C . SER A 1 855 ? 23.315 63.431 -17.368 1.00 8.46 ? 855 SER A C 1 ATOM 6921 O O . SER A 1 855 ? 23.861 64.114 -18.223 1.00 9.03 ? 855 SER A O 1 ATOM 6922 C CB . SER A 1 855 ? 22.434 63.990 -15.159 1.00 9.44 ? 855 SER A CB 1 ATOM 6923 O OG . SER A 1 855 ? 21.439 62.951 -15.106 1.00 10.62 ? 855 SER A OG 1 ATOM 6924 N N . SER A 1 856 ? 22.354 62.548 -17.649 1.00 8.46 ? 856 SER A N 1 ATOM 6925 C CA . SER A 1 856 ? 21.619 62.563 -18.935 1.00 9.36 ? 856 SER A CA 1 ATOM 6926 C C . SER A 1 856 ? 20.140 62.575 -18.542 1.00 10.06 ? 856 SER A C 1 ATOM 6927 O O . SER A 1 856 ? 19.606 61.535 -18.115 1.00 11.04 ? 856 SER A O 1 ATOM 6928 C CB . SER A 1 856 ? 21.966 61.317 -19.734 1.00 8.88 ? 856 SER A CB 1 ATOM 6929 O OG . SER A 1 856 ? 21.102 61.228 -20.884 1.00 9.91 ? 856 SER A OG 1 ATOM 6930 N N . LEU A 1 857 ? 19.459 63.737 -18.582 1.00 10.35 ? 857 LEU A N 1 ATOM 6931 C CA . LEU A 1 857 ? 18.109 63.840 -18.032 1.00 10.87 ? 857 LEU A CA 1 ATOM 6932 C C . LEU A 1 857 ? 17.029 63.535 -19.066 1.00 11.53 ? 857 LEU A C 1 ATOM 6933 O O . LEU A 1 857 ? 15.851 63.485 -18.717 1.00 12.44 ? 857 LEU A O 1 ATOM 6934 C CB . LEU A 1 857 ? 17.876 65.222 -17.422 1.00 11.32 ? 857 LEU A CB 1 ATOM 6935 C CG . LEU A 1 857 ? 18.704 65.510 -16.176 1.00 12.58 ? 857 LEU A CG 1 ATOM 6936 C CD1 . LEU A 1 857 ? 18.535 66.954 -15.670 1.00 14.75 ? 857 LEU A CD1 1 ATOM 6937 C CD2 . LEU A 1 857 ? 18.366 64.539 -15.046 1.00 13.84 ? 857 LEU A CD2 1 ATOM 6938 N N . ALA A 1 858 ? 17.455 63.281 -20.278 1.00 10.00 ? 858 ALA A N 1 ATOM 6939 C CA . ALA A 1 858 ? 16.533 62.864 -21.363 1.00 11.35 ? 858 ALA A CA 1 ATOM 6940 C C . ALA A 1 858 ? 17.341 62.166 -22.411 1.00 11.85 ? 858 ALA A C 1 ATOM 6941 O O . ALA A 1 858 ? 18.561 62.390 -22.553 1.00 11.10 ? 858 ALA A O 1 ATOM 6942 C CB . ALA A 1 858 ? 15.804 64.101 -21.970 1.00 13.09 ? 858 ALA A CB 1 ATOM 6943 N N . SER A 1 859 ? 16.681 61.291 -23.174 1.00 11.74 ? 859 SER A N 1 ATOM 6944 C CA . SER A 1 859 ? 17.334 60.543 -24.198 1.00 11.25 ? 859 SER A CA 1 ATOM 6945 C C . SER A 1 859 ? 18.098 61.500 -25.130 1.00 10.49 ? 859 SER A C 1 ATOM 6946 O O . SER A 1 859 ? 17.554 62.557 -25.500 1.00 11.84 ? 859 SER A O 1 ATOM 6947 C CB . SER A 1 859 ? 16.267 59.716 -24.986 1.00 12.29 ? 859 SER A CB 1 ATOM 6948 O OG . SER A 1 859 ? 16.837 58.955 -25.963 1.00 13.34 ? 859 SER A OG 1 ATOM 6949 N N . GLY A 1 860 ? 19.308 61.129 -25.524 1.00 11.07 ? 860 GLY A N 1 ATOM 6950 C CA . GLY A 1 860 ? 20.134 61.933 -26.413 1.00 10.99 ? 860 GLY A CA 1 ATOM 6951 C C . GLY A 1 860 ? 20.876 63.103 -25.754 1.00 10.23 ? 860 GLY A C 1 ATOM 6952 O O . GLY A 1 860 ? 21.632 63.786 -26.474 1.00 10.96 ? 860 GLY A O 1 ATOM 6953 N N . GLU A 1 861 ? 20.672 63.334 -24.461 1.00 10.41 ? 861 GLU A N 1 ATOM 6954 C CA . GLU A 1 861 ? 21.336 64.463 -23.774 1.00 10.32 ? 861 GLU A CA 1 ATOM 6955 C C . GLU A 1 861 ? 22.517 64.047 -22.888 1.00 10.91 ? 861 GLU A C 1 ATOM 6956 O O . GLU A 1 861 ? 22.533 62.942 -22.314 1.00 10.96 ? 861 GLU A O 1 ATOM 6957 C CB . GLU A 1 861 ? 20.367 65.190 -22.887 1.00 11.61 ? 861 GLU A CB 1 ATOM 6958 C CG . GLU A 1 861 ? 19.254 65.858 -23.652 1.00 13.31 ? 861 GLU A CG 1 ATOM 6959 C CD . GLU A 1 861 ? 18.364 66.708 -22.775 1.00 16.78 ? 861 GLU A CD 1 ATOM 6960 O OE1 . GLU A 1 861 ? 18.530 66.778 -21.523 1.00 15.83 ? 861 GLU A OE1 1 ATOM 6961 O OE2 . GLU A 1 861 ? 17.415 67.325 -23.348 1.00 18.37 ? 861 GLU A OE2 1 ATOM 6962 N N . LEU A 1 862 ? 23.483 64.945 -22.774 1.00 9.77 ? 862 LEU A N 1 ATOM 6963 C CA . LEU A 1 862 ? 24.527 64.894 -21.718 1.00 9.81 ? 862 LEU A CA 1 ATOM 6964 C C . LEU A 1 862 ? 24.509 66.267 -21.073 1.00 8.99 ? 862 LEU A C 1 ATOM 6965 O O . LEU A 1 862 ? 24.351 67.271 -21.796 1.00 9.66 ? 862 LEU A O 1 ATOM 6966 C CB . LEU A 1 862 ? 25.906 64.628 -22.354 1.00 9.68 ? 862 LEU A CB 1 ATOM 6967 C CG . LEU A 1 862 ? 26.221 63.259 -22.958 1.00 11.04 ? 862 LEU A CG 1 ATOM 6968 C CD1 . LEU A 1 862 ? 27.533 63.254 -23.640 1.00 11.18 ? 862 LEU A CD1 1 ATOM 6969 C CD2 . LEU A 1 862 ? 26.147 62.178 -21.891 1.00 11.40 ? 862 LEU A CD2 1 ATOM 6970 N N . GLU A 1 863 ? 24.751 66.366 -19.780 1.00 8.52 ? 863 GLU A N 1 ATOM 6971 C CA . GLU A 1 863 ? 24.953 67.691 -19.219 1.00 8.39 ? 863 GLU A CA 1 ATOM 6972 C C . GLU A 1 863 ? 25.943 67.614 -18.081 1.00 8.27 ? 863 GLU A C 1 ATOM 6973 O O . GLU A 1 863 ? 26.056 66.597 -17.406 1.00 7.36 ? 863 GLU A O 1 ATOM 6974 C CB . GLU A 1 863 ? 23.635 68.321 -18.772 1.00 9.49 ? 863 GLU A CB 1 ATOM 6975 C CG . GLU A 1 863 ? 23.054 67.792 -17.481 1.00 9.96 ? 863 GLU A CG 1 ATOM 6976 C CD . GLU A 1 863 ? 21.758 68.502 -17.115 1.00 9.17 ? 863 GLU A CD 1 ATOM 6977 O OE1 . GLU A 1 863 ? 20.876 68.525 -18.016 1.00 11.90 ? 863 GLU A OE1 1 ATOM 6978 O OE2 . GLU A 1 863 ? 21.607 69.016 -16.013 1.00 10.38 ? 863 GLU A OE2 1 ATOM 6979 N N . ILE A 1 864 ? 26.652 68.717 -17.877 1.00 7.89 ? 864 ILE A N 1 ATOM 6980 C CA . ILE A 1 864 ? 27.697 68.788 -16.836 1.00 8.18 ? 864 ILE A CA 1 ATOM 6981 C C . ILE A 1 864 ? 27.685 70.178 -16.218 1.00 7.50 ? 864 ILE A C 1 ATOM 6982 O O . ILE A 1 864 ? 27.692 71.207 -16.947 1.00 7.51 ? 864 ILE A O 1 ATOM 6983 C CB . ILE A 1 864 ? 29.059 68.408 -17.444 1.00 8.65 ? 864 ILE A CB 1 ATOM 6984 C CG1 . ILE A 1 864 ? 30.154 68.360 -16.378 1.00 11.33 ? 864 ILE A CG1 1 ATOM 6985 C CG2 . ILE A 1 864 ? 29.434 69.262 -18.617 1.00 11.88 ? 864 ILE A CG2 1 ATOM 6986 C CD1 . ILE A 1 864 ? 31.273 67.373 -16.850 1.00 12.59 ? 864 ILE A CD1 1 ATOM 6987 N N . MET A 1 865 ? 27.635 70.220 -14.902 1.00 6.96 ? 865 MET A N 1 ATOM 6988 C CA . MET A 1 865 ? 27.586 71.488 -14.191 1.00 7.76 ? 865 MET A CA 1 ATOM 6989 C C . MET A 1 865 ? 28.939 72.188 -14.243 1.00 8.44 ? 865 MET A C 1 ATOM 6990 O O . MET A 1 865 ? 29.981 71.565 -14.100 1.00 8.42 ? 865 MET A O 1 ATOM 6991 C CB . MET A 1 865 ? 27.123 71.255 -12.756 1.00 8.13 ? 865 MET A CB 1 ATOM 6992 C CG . MET A 1 865 ? 26.511 72.508 -12.101 1.00 8.35 ? 865 MET A CG 1 ATOM 6993 S SD . MET A 1 865 ? 24.889 72.907 -12.819 1.00 10.99 ? 865 MET A SD 1 ATOM 6994 C CE . MET A 1 865 ? 23.908 71.702 -11.891 1.00 11.58 ? 865 MET A CE 1 ATOM 6995 N N . GLN A 1 866 ? 28.911 73.513 -14.423 1.00 8.37 ? 866 GLN A N 1 ATOM 6996 C CA . GLN A 1 866 ? 30.123 74.342 -14.580 1.00 7.86 ? 866 GLN A CA 1 ATOM 6997 C C . GLN A 1 866 ? 30.520 75.038 -13.280 1.00 8.12 ? 866 GLN A C 1 ATOM 6998 O O . GLN A 1 866 ? 31.704 75.069 -12.897 1.00 8.76 ? 866 GLN A O 1 ATOM 6999 C CB . GLN A 1 866 ? 29.920 75.382 -15.692 1.00 8.86 ? 866 GLN A CB 1 ATOM 7000 C CG . GLN A 1 866 ? 29.607 74.776 -17.041 1.00 9.81 ? 866 GLN A CG 1 ATOM 7001 C CD . GLN A 1 866 ? 30.657 73.785 -17.463 1.00 8.94 ? 866 GLN A CD 1 ATOM 7002 O OE1 . GLN A 1 866 ? 31.785 74.156 -17.789 1.00 9.90 ? 866 GLN A OE1 1 ATOM 7003 N NE2 . GLN A 1 866 ? 30.297 72.501 -17.476 1.00 9.69 ? 866 GLN A NE2 1 ATOM 7004 N N . ASP A 1 867 ? 29.538 75.650 -12.613 1.00 8.46 ? 867 ASP A N 1 ATOM 7005 C CA . ASP A 1 867 ? 29.779 76.272 -11.288 1.00 8.25 ? 867 ASP A CA 1 ATOM 7006 C C . ASP A 1 867 ? 28.439 76.513 -10.623 1.00 7.83 ? 867 ASP A C 1 ATOM 7007 O O . ASP A 1 867 ? 27.369 76.392 -11.296 1.00 8.47 ? 867 ASP A O 1 ATOM 7008 C CB . ASP A 1 867 ? 30.604 77.567 -11.404 1.00 8.83 ? 867 ASP A CB 1 ATOM 7009 C CG . ASP A 1 867 ? 31.277 77.972 -10.099 1.00 8.43 ? 867 ASP A CG 1 ATOM 7010 O OD1 . ASP A 1 867 ? 31.147 77.313 -9.044 1.00 8.31 ? 867 ASP A OD1 1 ATOM 7011 O OD2 . ASP A 1 867 ? 31.996 78.992 -10.117 1.00 10.37 ? 867 ASP A OD2 1 ATOM 7012 N N . ARG A 1 868 ? 28.474 76.795 -9.345 1.00 7.95 ? 868 ARG A N 1 ATOM 7013 C CA . ARG A 1 868 ? 27.275 77.005 -8.582 1.00 8.27 ? 868 ARG A CA 1 ATOM 7014 C C . ARG A 1 868 ? 27.604 78.019 -7.492 1.00 8.83 ? 868 ARG A C 1 ATOM 7015 O O . ARG A 1 868 ? 28.637 77.952 -6.838 1.00 9.11 ? 868 ARG A O 1 ATOM 7016 C CB . ARG A 1 868 ? 26.759 75.662 -8.013 1.00 8.73 ? 868 ARG A CB 1 ATOM 7017 C CG . ARG A 1 868 ? 27.753 74.885 -7.141 1.00 9.69 ? 868 ARG A CG 1 ATOM 7018 C CD . ARG A 1 868 ? 27.517 73.379 -7.144 1.00 8.82 ? 868 ARG A CD 1 ATOM 7019 N NE . ARG A 1 868 ? 26.145 73.078 -6.715 1.00 8.42 ? 868 ARG A NE 1 ATOM 7020 C CZ . ARG A 1 868 ? 25.794 72.830 -5.462 1.00 8.40 ? 868 ARG A CZ 1 ATOM 7021 N NH1 . ARG A 1 868 ? 26.714 72.706 -4.480 1.00 8.45 ? 868 ARG A NH1 1 ATOM 7022 N NH2 . ARG A 1 868 ? 24.485 72.636 -5.205 1.00 8.89 ? 868 ARG A NH2 1 ATOM 7023 N N . ARG A 1 869 ? 26.674 78.950 -7.288 1.00 10.17 ? 869 ARG A N 1 ATOM 7024 C CA . ARG A 1 869 ? 26.825 80.018 -6.303 1.00 10.53 ? 869 ARG A CA 1 ATOM 7025 C C . ARG A 1 869 ? 25.554 80.027 -5.497 1.00 11.18 ? 869 ARG A C 1 ATOM 7026 O O . ARG A 1 869 ? 24.473 80.221 -6.066 1.00 12.16 ? 869 ARG A O 1 ATOM 7027 C CB . ARG A 1 869 ? 27.060 81.358 -7.001 1.00 11.20 ? 869 ARG A CB 1 ATOM 7028 C CG . ARG A 1 869 ? 27.248 82.512 -6.046 1.00 11.98 ? 869 ARG A CG 1 ATOM 7029 C CD . ARG A 1 869 ? 27.621 83.790 -6.791 1.00 13.88 ? 869 ARG A CD 1 ATOM 7030 N NE . ARG A 1 869 ? 27.805 84.950 -5.897 1.00 16.77 ? 869 ARG A NE 1 ATOM 7031 C CZ . ARG A 1 869 ? 28.950 85.293 -5.340 1.00 16.27 ? 869 ARG A CZ 1 ATOM 7032 N NH1 . ARG A 1 869 ? 30.041 84.563 -5.523 1.00 16.19 ? 869 ARG A NH1 1 ATOM 7033 N NH2 . ARG A 1 869 ? 29.010 86.388 -4.575 1.00 18.98 ? 869 ARG A NH2 1 ATOM 7034 N N . LEU A 1 870 ? 25.695 79.752 -4.210 1.00 12.44 ? 870 LEU A N 1 ATOM 7035 C CA . LEU A 1 870 ? 24.565 79.471 -3.311 1.00 13.11 ? 870 LEU A CA 1 ATOM 7036 C C . LEU A 1 870 ? 24.640 80.306 -2.067 1.00 13.14 ? 870 LEU A C 1 ATOM 7037 O O . LEU A 1 870 ? 25.614 80.283 -1.338 1.00 13.04 ? 870 LEU A O 1 ATOM 7038 C CB . LEU A 1 870 ? 24.567 77.998 -2.915 1.00 13.06 ? 870 LEU A CB 1 ATOM 7039 C CG . LEU A 1 870 ? 24.623 77.166 -4.200 1.00 16.39 ? 870 LEU A CG 1 ATOM 7040 C CD1 . LEU A 1 870 ? 25.236 75.826 -3.973 1.00 19.47 ? 870 LEU A CD1 1 ATOM 7041 C CD2 . LEU A 1 870 ? 23.302 77.126 -4.973 1.00 13.53 ? 870 LEU A CD2 1 ATOM 7042 N N . ALA A 1 871 ? 23.535 80.998 -1.800 1.00 13.66 ? 871 ALA A N 1 ATOM 7043 C CA . ALA A 1 871 ? 23.509 81.939 -0.712 1.00 15.10 ? 871 ALA A CA 1 ATOM 7044 C C . ALA A 1 871 ? 23.323 81.284 0.664 1.00 16.25 ? 871 ALA A C 1 ATOM 7045 O O . ALA A 1 871 ? 23.726 81.827 1.698 1.00 18.35 ? 871 ALA A O 1 ATOM 7046 C CB . ALA A 1 871 ? 22.396 83.001 -0.934 1.00 15.67 ? 871 ALA A CB 1 ATOM 7047 N N . SER A 1 872 ? 22.720 80.106 0.670 1.00 15.95 ? 872 SER A N 1 ATOM 7048 C CA . SER A 1 872 ? 22.296 79.476 1.908 1.00 16.80 ? 872 SER A CA 1 ATOM 7049 C C . SER A 1 872 ? 23.178 78.316 2.322 1.00 15.15 ? 872 SER A C 1 ATOM 7050 O O . SER A 1 872 ? 23.800 77.654 1.472 1.00 16.27 ? 872 SER A O 1 ATOM 7051 C CB . SER A 1 872 ? 20.854 78.986 1.747 1.00 18.37 ? 872 SER A CB 1 ATOM 7052 O OG . SER A 1 872 ? 19.988 80.098 1.570 1.00 22.74 ? 872 SER A OG 1 ATOM 7053 N N . ASP A 1 873 ? 23.239 78.100 3.629 1.00 15.47 ? 873 ASP A N 1 ATOM 7054 C CA . ASP A 1 873 ? 23.788 76.869 4.207 1.00 14.94 ? 873 ASP A CA 1 ATOM 7055 C C . ASP A 1 873 ? 22.772 75.728 4.028 1.00 14.76 ? 873 ASP A C 1 ATOM 7056 O O . ASP A 1 873 ? 21.564 75.960 4.046 1.00 16.29 ? 873 ASP A O 1 ATOM 7057 C CB . ASP A 1 873 ? 24.095 77.088 5.680 1.00 15.64 ? 873 ASP A CB 1 ATOM 7058 C CG . ASP A 1 873 ? 24.574 75.830 6.356 1.00 15.64 ? 873 ASP A CG 1 ATOM 7059 O OD1 . ASP A 1 873 ? 25.663 75.328 5.976 1.00 16.92 ? 873 ASP A OD1 1 ATOM 7060 O OD2 . ASP A 1 873 ? 23.904 75.261 7.239 1.00 17.70 ? 873 ASP A OD2 1 ATOM 7061 N N . ASP A 1 874 ? 23.278 74.504 3.829 1.00 13.01 ? 874 ASP A N 1 ATOM 7062 C CA . ASP A 1 874 ? 22.430 73.329 3.610 1.00 12.04 ? 874 ASP A CA 1 ATOM 7063 C C . ASP A 1 874 ? 22.419 72.349 4.786 1.00 12.16 ? 874 ASP A C 1 ATOM 7064 O O . ASP A 1 874 ? 22.191 71.142 4.601 1.00 13.58 ? 874 ASP A O 1 ATOM 7065 C CB . ASP A 1 874 ? 22.774 72.623 2.295 1.00 11.70 ? 874 ASP A CB 1 ATOM 7066 C CG . ASP A 1 874 ? 24.249 72.281 2.161 1.00 10.42 ? 874 ASP A CG 1 ATOM 7067 O OD1 . ASP A 1 874 ? 25.070 72.605 3.081 1.00 12.88 ? 874 ASP A OD1 1 ATOM 7068 O OD2 . ASP A 1 874 ? 24.594 71.683 1.130 1.00 10.34 ? 874 ASP A OD2 1 ATOM 7069 N N . GLU A 1 875 ? 22.669 72.855 5.991 1.00 12.31 ? 875 GLU A N 1 ATOM 7070 C CA A GLU A 1 875 ? 22.431 72.142 7.264 0.50 12.93 ? 875 GLU A CA 1 ATOM 7071 C CA B GLU A 1 875 ? 22.344 72.076 7.206 0.50 12.53 ? 875 GLU A CA 1 ATOM 7072 C C . GLU A 1 875 ? 23.235 70.860 7.442 1.00 13.11 ? 875 GLU A C 1 ATOM 7073 O O . GLU A 1 875 ? 22.847 69.950 8.161 1.00 13.47 ? 875 GLU A O 1 ATOM 7074 C CB A GLU A 1 875 ? 20.921 71.929 7.525 0.50 13.84 ? 875 GLU A CB 1 ATOM 7075 C CB B GLU A 1 875 ? 20.867 71.586 7.200 0.50 12.62 ? 875 GLU A CB 1 ATOM 7076 C CG A GLU A 1 875 ? 20.093 73.180 7.240 0.50 16.05 ? 875 GLU A CG 1 ATOM 7077 C CG B GLU A 1 875 ? 19.788 72.655 7.063 0.50 13.27 ? 875 GLU A CG 1 ATOM 7078 C CD A GLU A 1 875 ? 18.762 73.217 7.963 0.50 18.96 ? 875 GLU A CD 1 ATOM 7079 C CD B GLU A 1 875 ? 18.392 72.107 7.341 0.50 13.45 ? 875 GLU A CD 1 ATOM 7080 O OE1 A GLU A 1 875 ? 18.758 73.161 9.212 0.50 22.22 ? 875 GLU A OE1 1 ATOM 7081 O OE1 B GLU A 1 875 ? 17.976 71.127 6.682 0.50 14.65 ? 875 GLU A OE1 1 ATOM 7082 O OE2 A GLU A 1 875 ? 17.722 73.323 7.281 0.50 19.47 ? 875 GLU A OE2 1 ATOM 7083 O OE2 B GLU A 1 875 ? 17.706 72.657 8.239 0.50 18.51 ? 875 GLU A OE2 1 ATOM 7084 N N . ARG A 1 876 ? 24.413 70.836 6.829 1.00 11.73 ? 876 ARG A N 1 ATOM 7085 C CA . ARG A 1 876 ? 25.322 69.676 6.983 1.00 11.66 ? 876 ARG A CA 1 ATOM 7086 C C . ARG A 1 876 ? 26.590 70.032 7.776 1.00 12.03 ? 876 ARG A C 1 ATOM 7087 O O . ARG A 1 876 ? 27.532 69.227 7.850 1.00 12.45 ? 876 ARG A O 1 ATOM 7088 C CB . ARG A 1 876 ? 25.671 69.044 5.619 1.00 11.65 ? 876 ARG A CB 1 ATOM 7089 C CG . ARG A 1 876 ? 24.434 68.484 4.894 1.00 11.57 ? 876 ARG A CG 1 ATOM 7090 C CD . ARG A 1 876 ? 23.656 67.552 5.785 1.00 12.13 ? 876 ARG A CD 1 ATOM 7091 N NE . ARG A 1 876 ? 22.568 66.812 5.149 1.00 11.59 ? 876 ARG A NE 1 ATOM 7092 C CZ . ARG A 1 876 ? 21.374 67.323 4.897 1.00 12.09 ? 876 ARG A CZ 1 ATOM 7093 N NH1 . ARG A 1 876 ? 21.140 68.621 5.113 1.00 11.15 ? 876 ARG A NH1 1 ATOM 7094 N NH2 . ARG A 1 876 ? 20.418 66.541 4.419 1.00 11.23 ? 876 ARG A NH2 1 ATOM 7095 N N . GLY A 1 877 ? 26.623 71.212 8.390 1.00 12.32 ? 877 GLY A N 1 ATOM 7096 C CA . GLY A 1 877 ? 27.701 71.565 9.293 1.00 11.95 ? 877 GLY A CA 1 ATOM 7097 C C . GLY A 1 877 ? 28.654 72.640 8.813 1.00 12.00 ? 877 GLY A C 1 ATOM 7098 O O . GLY A 1 877 ? 29.456 73.155 9.608 1.00 12.94 ? 877 GLY A O 1 ATOM 7099 N N . LEU A 1 878 ? 28.571 72.994 7.538 1.00 11.93 ? 878 LEU A N 1 ATOM 7100 C CA . LEU A 1 878 ? 29.508 73.973 6.996 1.00 13.32 ? 878 LEU A CA 1 ATOM 7101 C C . LEU A 1 878 ? 29.258 75.389 7.530 1.00 14.20 ? 878 LEU A C 1 ATOM 7102 O O . LEU A 1 878 ? 30.216 76.141 7.772 1.00 14.75 ? 878 LEU A O 1 ATOM 7103 C CB . LEU A 1 878 ? 29.468 73.922 5.469 1.00 12.94 ? 878 LEU A CB 1 ATOM 7104 C CG . LEU A 1 878 ? 30.288 74.983 4.714 1.00 12.45 ? 878 LEU A CG 1 ATOM 7105 C CD1 . LEU A 1 878 ? 31.761 75.015 5.147 1.00 12.89 ? 878 LEU A CD1 1 ATOM 7106 C CD2 . LEU A 1 878 ? 30.188 74.787 3.216 1.00 12.62 ? 878 LEU A CD2 1 ATOM 7107 N N . GLY A 1 879 ? 27.981 75.746 7.687 1.00 13.51 ? 879 GLY A N 1 ATOM 7108 C CA . GLY A 1 879 ? 27.605 77.047 8.238 1.00 15.12 ? 879 GLY A CA 1 ATOM 7109 C C . GLY A 1 879 ? 27.907 78.236 7.338 1.00 16.74 ? 879 GLY A C 1 ATOM 7110 O O . GLY A 1 879 ? 28.104 79.357 7.808 1.00 18.31 ? 879 GLY A O 1 ATOM 7111 N N . GLN A 1 880 ? 27.943 77.996 6.034 1.00 15.18 ? 880 GLN A N 1 ATOM 7112 C CA . GLN A 1 880 ? 27.989 79.074 5.052 1.00 15.36 ? 880 GLN A CA 1 ATOM 7113 C C . GLN A 1 880 ? 27.447 78.536 3.728 1.00 15.05 ? 880 GLN A C 1 ATOM 7114 O O . GLN A 1 880 ? 27.399 77.314 3.520 1.00 15.70 ? 880 GLN A O 1 ATOM 7115 C CB . GLN A 1 880 ? 29.432 79.624 4.894 1.00 15.10 ? 880 GLN A CB 1 ATOM 7116 C CG . GLN A 1 880 ? 30.496 78.598 4.441 1.00 16.12 ? 880 GLN A CG 1 ATOM 7117 C CD . GLN A 1 880 ? 31.750 79.241 3.880 1.00 15.29 ? 880 GLN A CD 1 ATOM 7118 O OE1 . GLN A 1 880 ? 32.677 79.533 4.601 1.00 15.00 ? 880 GLN A OE1 1 ATOM 7119 N NE2 . GLN A 1 880 ? 31.778 79.427 2.579 1.00 17.36 ? 880 GLN A NE2 1 ATOM 7120 N N . GLY A 1 881 ? 27.078 79.441 2.836 1.00 15.93 ? 881 GLY A N 1 ATOM 7121 C CA . GLY A 1 881 ? 26.831 79.073 1.450 1.00 16.00 ? 881 GLY A CA 1 ATOM 7122 C C . GLY A 1 881 ? 28.122 78.960 0.652 1.00 14.84 ? 881 GLY A C 1 ATOM 7123 O O . GLY A 1 881 ? 29.235 78.847 1.218 1.00 15.80 ? 881 GLY A O 1 ATOM 7124 N N . VAL A 1 882 ? 27.973 79.017 -0.671 1.00 13.57 ? 882 VAL A N 1 ATOM 7125 C CA . VAL A 1 882 ? 29.120 79.037 -1.553 1.00 12.69 ? 882 VAL A CA 1 ATOM 7126 C C . VAL A 1 882 ? 29.052 80.365 -2.305 1.00 12.60 ? 882 VAL A C 1 ATOM 7127 O O . VAL A 1 882 ? 28.297 80.512 -3.259 1.00 12.28 ? 882 VAL A O 1 ATOM 7128 C CB . VAL A 1 882 ? 29.091 77.836 -2.495 1.00 12.97 ? 882 VAL A CB 1 ATOM 7129 C CG1 . VAL A 1 882 ? 30.248 77.879 -3.467 1.00 13.87 ? 882 VAL A CG1 1 ATOM 7130 C CG2 . VAL A 1 882 ? 29.142 76.525 -1.688 1.00 14.48 ? 882 VAL A CG2 1 ATOM 7131 N N . LEU A 1 883 ? 29.835 81.332 -1.815 1.00 12.68 ? 883 LEU A N 1 ATOM 7132 C CA . LEU A 1 883 ? 29.796 82.703 -2.361 1.00 13.23 ? 883 LEU A CA 1 ATOM 7133 C C . LEU A 1 883 ? 31.190 83.211 -2.683 1.00 14.63 ? 883 LEU A C 1 ATOM 7134 O O . LEU A 1 883 ? 31.375 84.421 -2.846 1.00 16.83 ? 883 LEU A O 1 ATOM 7135 C CB . LEU A 1 883 ? 29.085 83.692 -1.409 1.00 14.73 ? 883 LEU A CB 1 ATOM 7136 C CG . LEU A 1 883 ? 27.588 83.419 -1.181 1.00 14.92 ? 883 LEU A CG 1 ATOM 7137 C CD1 . LEU A 1 883 ? 26.977 84.302 -0.055 1.00 17.02 ? 883 LEU A CD1 1 ATOM 7138 C CD2 . LEU A 1 883 ? 26.774 83.588 -2.462 1.00 16.14 ? 883 LEU A CD2 1 ATOM 7139 N N . ASP A 1 884 ? 32.144 82.303 -2.795 1.00 12.48 ? 884 ASP A N 1 ATOM 7140 C CA . ASP A 1 884 ? 33.561 82.598 -3.013 1.00 11.74 ? 884 ASP A CA 1 ATOM 7141 C C . ASP A 1 884 ? 34.047 82.119 -4.372 1.00 11.78 ? 884 ASP A C 1 ATOM 7142 O O . ASP A 1 884 ? 35.227 81.837 -4.554 1.00 12.05 ? 884 ASP A O 1 ATOM 7143 C CB . ASP A 1 884 ? 34.437 82.000 -1.908 1.00 12.96 ? 884 ASP A CB 1 ATOM 7144 C CG . ASP A 1 884 ? 34.233 80.496 -1.697 1.00 13.62 ? 884 ASP A CG 1 ATOM 7145 O OD1 . ASP A 1 884 ? 33.427 79.817 -2.416 1.00 13.17 ? 884 ASP A OD1 1 ATOM 7146 O OD2 . ASP A 1 884 ? 34.872 79.942 -0.755 1.00 16.10 ? 884 ASP A OD2 1 ATOM 7147 N N . ASN A 1 885 ? 33.141 82.055 -5.334 1.00 10.85 ? 885 ASN A N 1 ATOM 7148 C CA . ASN A 1 885 ? 33.471 81.667 -6.682 1.00 11.25 ? 885 ASN A CA 1 ATOM 7149 C C . ASN A 1 885 ? 34.563 82.514 -7.277 1.00 12.36 ? 885 ASN A C 1 ATOM 7150 O O . ASN A 1 885 ? 34.684 83.711 -6.958 1.00 12.60 ? 885 ASN A O 1 ATOM 7151 C CB . ASN A 1 885 ? 32.238 81.803 -7.562 1.00 10.91 ? 885 ASN A CB 1 ATOM 7152 C CG . ASN A 1 885 ? 31.044 81.132 -6.969 1.00 10.98 ? 885 ASN A CG 1 ATOM 7153 O OD1 . ASN A 1 885 ? 30.391 81.655 -6.081 1.00 12.54 ? 885 ASN A OD1 1 ATOM 7154 N ND2 . ASN A 1 885 ? 30.754 79.921 -7.452 1.00 10.98 ? 885 ASN A ND2 1 ATOM 7155 N N . LYS A 1 886 ? 35.338 81.923 -8.169 1.00 11.81 ? 886 LYS A N 1 ATOM 7156 C CA . LYS A 1 886 ? 36.350 82.672 -8.896 1.00 13.86 ? 886 LYS A CA 1 ATOM 7157 C C . LYS A 1 886 ? 36.443 82.085 -10.292 1.00 11.98 ? 886 LYS A C 1 ATOM 7158 O O . LYS A 1 886 ? 36.052 80.927 -10.529 1.00 11.47 ? 886 LYS A O 1 ATOM 7159 C CB . LYS A 1 886 ? 37.692 82.629 -8.166 1.00 15.64 ? 886 LYS A CB 1 ATOM 7160 C CG . LYS A 1 886 ? 38.208 81.217 -7.957 1.00 16.71 ? 886 LYS A CG 1 ATOM 7161 C CD . LYS A 1 886 ? 39.279 81.094 -6.832 1.00 17.83 ? 886 LYS A CD 1 ATOM 7162 C CE . LYS A 1 886 ? 40.665 81.409 -7.378 1.00 19.21 ? 886 LYS A CE 1 ATOM 7163 N NZ . LYS A 1 886 ? 41.778 81.691 -6.400 1.00 20.57 ? 886 LYS A NZ 1 ATOM 7164 N N . PRO A 1 887 ? 36.899 82.857 -11.251 1.00 9.78 ? 887 PRO A N 1 ATOM 7165 C CA . PRO A 1 887 ? 36.992 82.360 -12.624 1.00 9.99 ? 887 PRO A CA 1 ATOM 7166 C C . PRO A 1 887 ? 37.823 81.096 -12.731 1.00 9.93 ? 887 PRO A C 1 ATOM 7167 O O . PRO A 1 887 ? 38.864 80.960 -12.112 1.00 10.14 ? 887 PRO A O 1 ATOM 7168 C CB . PRO A 1 887 ? 37.631 83.533 -13.388 1.00 10.95 ? 887 PRO A CB 1 ATOM 7169 C CG . PRO A 1 887 ? 37.209 84.760 -12.594 1.00 12.05 ? 887 PRO A CG 1 ATOM 7170 C CD . PRO A 1 887 ? 37.207 84.306 -11.164 1.00 10.71 ? 887 PRO A CD 1 ATOM 7171 N N . VAL A 1 888 ? 37.316 80.150 -13.508 1.00 8.87 ? 888 VAL A N 1 ATOM 7172 C CA . VAL A 1 888 ? 37.979 78.874 -13.704 1.00 8.59 ? 888 VAL A CA 1 ATOM 7173 C C . VAL A 1 888 ? 37.898 78.511 -15.166 1.00 7.94 ? 888 VAL A C 1 ATOM 7174 O O . VAL A 1 888 ? 36.851 78.734 -15.839 1.00 9.24 ? 888 VAL A O 1 ATOM 7175 C CB . VAL A 1 888 ? 37.334 77.761 -12.814 1.00 9.20 ? 888 VAL A CB 1 ATOM 7176 C CG1 . VAL A 1 888 ? 35.805 77.661 -13.033 1.00 10.48 ? 888 VAL A CG1 1 ATOM 7177 C CG2 . VAL A 1 888 ? 37.989 76.422 -13.091 1.00 8.98 ? 888 VAL A CG2 1 ATOM 7178 N N . LEU A 1 889 ? 38.970 77.954 -15.702 1.00 6.92 ? 889 LEU A N 1 ATOM 7179 C CA . LEU A 1 889 ? 38.969 77.457 -17.075 1.00 8.28 ? 889 LEU A CA 1 ATOM 7180 C C . LEU A 1 889 ? 38.788 75.934 -17.096 1.00 8.22 ? 889 LEU A C 1 ATOM 7181 O O . LEU A 1 889 ? 39.696 75.176 -16.772 1.00 8.76 ? 889 LEU A O 1 ATOM 7182 C CB . LEU A 1 889 ? 40.283 77.843 -17.762 1.00 8.94 ? 889 LEU A CB 1 ATOM 7183 C CG . LEU A 1 889 ? 40.384 77.457 -19.242 1.00 10.78 ? 889 LEU A CG 1 ATOM 7184 C CD1 . LEU A 1 889 ? 39.430 78.300 -20.084 1.00 11.94 ? 889 LEU A CD1 1 ATOM 7185 C CD2 . LEU A 1 889 ? 41.817 77.549 -19.736 1.00 14.17 ? 889 LEU A CD2 1 ATOM 7186 N N . HIS A 1 890 ? 37.578 75.515 -17.417 1.00 7.04 ? 890 HIS A N 1 ATOM 7187 C CA . HIS A 1 890 ? 37.243 74.092 -17.589 1.00 7.07 ? 890 HIS A CA 1 ATOM 7188 C C . HIS A 1 890 ? 37.627 73.615 -18.962 1.00 7.68 ? 890 HIS A C 1 ATOM 7189 O O . HIS A 1 890 ? 37.418 74.351 -19.957 1.00 8.03 ? 890 HIS A O 1 ATOM 7190 C CB . HIS A 1 890 ? 35.754 73.874 -17.380 1.00 7.34 ? 890 HIS A CB 1 ATOM 7191 C CG . HIS A 1 890 ? 35.327 74.026 -15.967 1.00 7.58 ? 890 HIS A CG 1 ATOM 7192 N ND1 . HIS A 1 890 ? 36.147 73.675 -14.903 1.00 9.60 ? 890 HIS A ND1 1 ATOM 7193 C CD2 . HIS A 1 890 ? 34.158 74.451 -15.433 1.00 9.68 ? 890 HIS A CD2 1 ATOM 7194 C CE1 . HIS A 1 890 ? 35.482 73.880 -13.779 1.00 10.51 ? 890 HIS A CE1 1 ATOM 7195 N NE2 . HIS A 1 890 ? 34.271 74.347 -14.068 1.00 9.24 ? 890 HIS A NE2 1 ATOM 7196 N N . ILE A 1 891 ? 38.159 72.396 -19.057 1.00 6.43 ? 891 ILE A N 1 ATOM 7197 C CA . ILE A 1 891 ? 38.582 71.851 -20.347 1.00 6.97 ? 891 ILE A CA 1 ATOM 7198 C C . ILE A 1 891 ? 37.922 70.509 -20.614 1.00 6.45 ? 891 ILE A C 1 ATOM 7199 O O . ILE A 1 891 ? 37.649 69.743 -19.664 1.00 6.30 ? 891 ILE A O 1 ATOM 7200 C CB . ILE A 1 891 ? 40.115 71.766 -20.472 1.00 7.08 ? 891 ILE A CB 1 ATOM 7201 C CG1 . ILE A 1 891 ? 40.723 70.774 -19.497 1.00 8.97 ? 891 ILE A CG1 1 ATOM 7202 C CG2 . ILE A 1 891 ? 40.718 73.172 -20.220 1.00 9.87 ? 891 ILE A CG2 1 ATOM 7203 C CD1 . ILE A 1 891 ? 42.244 70.600 -19.708 1.00 9.67 ? 891 ILE A CD1 1 ATOM 7204 N N . TYR A 1 892 ? 37.660 70.233 -21.880 1.00 6.39 ? 892 TYR A N 1 ATOM 7205 C CA . TYR A 1 892 ? 36.963 69.008 -22.299 1.00 6.03 ? 892 TYR A CA 1 ATOM 7206 C C . TYR A 1 892 ? 37.423 68.573 -23.666 1.00 6.19 ? 892 TYR A C 1 ATOM 7207 O O . TYR A 1 892 ? 37.993 69.342 -24.438 1.00 7.02 ? 892 TYR A O 1 ATOM 7208 C CB . TYR A 1 892 ? 35.448 69.249 -22.440 1.00 6.92 ? 892 TYR A CB 1 ATOM 7209 C CG . TYR A 1 892 ? 34.796 69.909 -21.260 1.00 6.28 ? 892 TYR A CG 1 ATOM 7210 C CD1 . TYR A 1 892 ? 34.737 71.308 -21.136 1.00 6.72 ? 892 TYR A CD1 1 ATOM 7211 C CD2 . TYR A 1 892 ? 34.231 69.148 -20.219 1.00 6.55 ? 892 TYR A CD2 1 ATOM 7212 C CE1 . TYR A 1 892 ? 34.144 71.911 -20.063 1.00 7.53 ? 892 TYR A CE1 1 ATOM 7213 C CE2 . TYR A 1 892 ? 33.643 69.733 -19.135 1.00 7.73 ? 892 TYR A CE2 1 ATOM 7214 C CZ . TYR A 1 892 ? 33.606 71.108 -19.053 1.00 6.94 ? 892 TYR A CZ 1 ATOM 7215 O OH . TYR A 1 892 ? 33.004 71.656 -17.949 1.00 8.52 ? 892 TYR A OH 1 ATOM 7216 N N . ARG A 1 893 ? 37.145 67.310 -23.982 1.00 6.31 ? 893 ARG A N 1 ATOM 7217 C CA . ARG A 1 893 ? 37.213 66.834 -25.381 1.00 7.50 ? 893 ARG A CA 1 ATOM 7218 C C . ARG A 1 893 ? 35.880 66.201 -25.705 1.00 7.68 ? 893 ARG A C 1 ATOM 7219 O O . ARG A 1 893 ? 35.249 65.593 -24.855 1.00 7.96 ? 893 ARG A O 1 ATOM 7220 C CB . ARG A 1 893 ? 38.323 65.807 -25.588 1.00 7.53 ? 893 ARG A CB 1 ATOM 7221 C CG . ARG A 1 893 ? 39.737 66.336 -25.356 1.00 8.26 ? 893 ARG A CG 1 ATOM 7222 C CD . ARG A 1 893 ? 40.211 67.405 -26.384 1.00 9.54 ? 893 ARG A CD 1 ATOM 7223 N NE . ARG A 1 893 ? 40.333 66.884 -27.736 1.00 9.82 ? 893 ARG A NE 1 ATOM 7224 C CZ . ARG A 1 893 ? 41.408 66.269 -28.175 1.00 9.47 ? 893 ARG A CZ 1 ATOM 7225 N NH1 . ARG A 1 893 ? 42.461 66.084 -27.360 1.00 11.79 ? 893 ARG A NH1 1 ATOM 7226 N NH2 . ARG A 1 893 ? 41.481 65.833 -29.426 1.00 12.20 ? 893 ARG A NH2 1 ATOM 7227 N N . LEU A 1 894 ? 35.457 66.365 -26.969 1.00 8.48 ? 894 LEU A N 1 ATOM 7228 C CA . LEU A 1 894 ? 34.147 65.876 -27.418 1.00 9.84 ? 894 LEU A CA 1 ATOM 7229 C C . LEU A 1 894 ? 34.367 64.910 -28.558 1.00 9.56 ? 894 LEU A C 1 ATOM 7230 O O . LEU A 1 894 ? 34.900 65.284 -29.597 1.00 10.73 ? 894 LEU A O 1 ATOM 7231 C CB . LEU A 1 894 ? 33.300 67.056 -27.883 1.00 10.31 ? 894 LEU A CB 1 ATOM 7232 C CG . LEU A 1 894 ? 31.859 66.689 -28.234 1.00 11.83 ? 894 LEU A CG 1 ATOM 7233 C CD1 . LEU A 1 894 ? 31.116 66.192 -27.015 1.00 15.85 ? 894 LEU A CD1 1 ATOM 7234 C CD2 . LEU A 1 894 ? 31.155 67.883 -28.840 1.00 14.95 ? 894 LEU A CD2 1 ATOM 7235 N N . VAL A 1 895 ? 34.010 63.631 -28.333 1.00 9.87 ? 895 VAL A N 1 ATOM 7236 C CA . VAL A 1 895 ? 34.253 62.575 -29.309 1.00 10.92 ? 895 VAL A CA 1 ATOM 7237 C C . VAL A 1 895 ? 32.940 61.947 -29.779 1.00 11.52 ? 895 VAL A C 1 ATOM 7238 O O . VAL A 1 895 ? 32.261 61.261 -29.028 1.00 10.70 ? 895 VAL A O 1 ATOM 7239 C CB . VAL A 1 895 ? 35.160 61.481 -28.687 1.00 10.62 ? 895 VAL A CB 1 ATOM 7240 C CG1 . VAL A 1 895 ? 35.548 60.469 -29.749 1.00 13.48 ? 895 VAL A CG1 1 ATOM 7241 C CG2 . VAL A 1 895 ? 36.408 62.139 -28.072 1.00 13.17 ? 895 VAL A CG2 1 ATOM 7242 N N . LEU A 1 896 ? 32.576 62.216 -31.034 1.00 11.45 ? 896 LEU A N 1 ATOM 7243 C CA . LEU A 1 896 ? 31.419 61.598 -31.695 1.00 11.88 ? 896 LEU A CA 1 ATOM 7244 C C . LEU A 1 896 ? 31.962 60.458 -32.531 1.00 11.94 ? 896 LEU A C 1 ATOM 7245 O O . LEU A 1 896 ? 32.915 60.617 -33.289 1.00 12.85 ? 896 LEU A O 1 ATOM 7246 C CB . LEU A 1 896 ? 30.739 62.625 -32.613 1.00 11.82 ? 896 LEU A CB 1 ATOM 7247 C CG . LEU A 1 896 ? 29.568 62.004 -33.425 1.00 13.28 ? 896 LEU A CG 1 ATOM 7248 C CD1 . LEU A 1 896 ? 28.455 61.712 -32.509 1.00 14.32 ? 896 LEU A CD1 1 ATOM 7249 C CD2 . LEU A 1 896 ? 29.111 62.998 -34.476 1.00 14.61 ? 896 LEU A CD2 1 ATOM 7250 N N . GLU A 1 897 ? 31.379 59.259 -32.370 1.00 11.57 ? 897 GLU A N 1 ATOM 7251 C CA . GLU A 1 897 ? 31.921 58.078 -33.053 1.00 12.82 ? 897 GLU A CA 1 ATOM 7252 C C . GLU A 1 897 ? 30.787 57.163 -33.504 1.00 12.76 ? 897 GLU A C 1 ATOM 7253 O O . GLU A 1 897 ? 29.764 57.079 -32.855 1.00 12.42 ? 897 GLU A O 1 ATOM 7254 C CB . GLU A 1 897 ? 32.810 57.279 -32.098 1.00 14.14 ? 897 GLU A CB 1 ATOM 7255 C CG . GLU A 1 897 ? 33.985 58.034 -31.502 1.00 16.72 ? 897 GLU A CG 1 ATOM 7256 C CD . GLU A 1 897 ? 34.697 57.203 -30.439 1.00 15.35 ? 897 GLU A CD 1 ATOM 7257 O OE1 . GLU A 1 897 ? 34.095 56.997 -29.347 1.00 20.74 ? 897 GLU A OE1 1 ATOM 7258 O OE2 . GLU A 1 897 ? 35.865 56.843 -30.745 1.00 22.49 ? 897 GLU A OE2 1 ATOM 7259 N N . LYS A 1 898 ? 31.042 56.465 -34.607 1.00 13.85 ? 898 LYS A N 1 ATOM 7260 C CA . LYS A 1 898 ? 30.227 55.323 -35.013 1.00 15.94 ? 898 LYS A CA 1 ATOM 7261 C C . LYS A 1 898 ? 30.666 54.061 -34.267 1.00 15.39 ? 898 LYS A C 1 ATOM 7262 O O . LYS A 1 898 ? 31.849 53.696 -34.262 1.00 18.27 ? 898 LYS A O 1 ATOM 7263 C CB . LYS A 1 898 ? 30.375 55.120 -36.515 1.00 16.26 ? 898 LYS A CB 1 ATOM 7264 C CG . LYS A 1 898 ? 29.783 56.242 -37.370 1.00 21.33 ? 898 LYS A CG 1 ATOM 7265 C CD . LYS A 1 898 ? 28.531 56.914 -36.756 1.00 27.14 ? 898 LYS A CD 1 ATOM 7266 C CE . LYS A 1 898 ? 27.176 56.259 -37.101 1.00 28.76 ? 898 LYS A CE 1 ATOM 7267 N NZ . LYS A 1 898 ? 27.132 54.762 -37.136 1.00 32.01 ? 898 LYS A NZ 1 ATOM 7268 N N . VAL A 1 899 ? 29.716 53.416 -33.607 1.00 15.64 ? 899 VAL A N 1 ATOM 7269 C CA . VAL A 1 899 ? 30.054 52.268 -32.761 1.00 15.26 ? 899 VAL A CA 1 ATOM 7270 C C . VAL A 1 899 ? 29.332 50.960 -33.116 1.00 15.35 ? 899 VAL A C 1 ATOM 7271 O O . VAL A 1 899 ? 29.464 49.965 -32.408 1.00 15.36 ? 899 VAL A O 1 ATOM 7272 C CB . VAL A 1 899 ? 29.850 52.573 -31.250 1.00 15.06 ? 899 VAL A CB 1 ATOM 7273 C CG1 . VAL A 1 899 ? 30.878 53.610 -30.743 1.00 15.92 ? 899 VAL A CG1 1 ATOM 7274 C CG2 . VAL A 1 899 ? 28.470 53.055 -30.974 1.00 14.49 ? 899 VAL A CG2 1 ATOM 7275 N N . ASN A 1 900 ? 28.578 50.953 -34.215 1.00 15.98 ? 900 ASN A N 1 ATOM 7276 C CA . ASN A 1 900 ? 27.876 49.721 -34.601 1.00 17.20 ? 900 ASN A CA 1 ATOM 7277 C C . ASN A 1 900 ? 28.818 48.533 -34.851 1.00 16.49 ? 900 ASN A C 1 ATOM 7278 O O . ASN A 1 900 ? 28.383 47.373 -34.743 1.00 18.76 ? 900 ASN A O 1 ATOM 7279 C CB . ASN A 1 900 ? 26.997 49.937 -35.843 1.00 17.68 ? 900 ASN A CB 1 ATOM 7280 C CG . ASN A 1 900 ? 27.764 50.474 -37.002 1.00 20.38 ? 900 ASN A CG 1 ATOM 7281 O OD1 . ASN A 1 900 ? 28.307 51.562 -36.946 1.00 23.49 ? 900 ASN A OD1 1 ATOM 7282 N ND2 . ASN A 1 900 ? 27.806 49.708 -38.099 1.00 25.50 ? 900 ASN A ND2 1 ATOM 7283 N N . ASN A 1 901 ? 30.074 48.787 -35.188 1.00 15.85 ? 901 ASN A N 1 ATOM 7284 C CA . ASN A 1 901 ? 31.035 47.701 -35.423 1.00 16.29 ? 901 ASN A CA 1 ATOM 7285 C C . ASN A 1 901 ? 31.821 47.284 -34.176 1.00 15.23 ? 901 ASN A C 1 ATOM 7286 O O . ASN A 1 901 ? 32.594 46.332 -34.220 1.00 15.75 ? 901 ASN A O 1 ATOM 7287 C CB . ASN A 1 901 ? 32.024 48.072 -36.524 1.00 17.71 ? 901 ASN A CB 1 ATOM 7288 C CG . ASN A 1 901 ? 31.428 47.991 -37.903 1.00 21.09 ? 901 ASN A CG 1 ATOM 7289 O OD1 . ASN A 1 901 ? 30.719 47.046 -38.244 1.00 25.41 ? 901 ASN A OD1 1 ATOM 7290 N ND2 . ASN A 1 901 ? 31.733 48.988 -38.726 1.00 26.04 ? 901 ASN A ND2 1 ATOM 7291 N N . CYS A 1 902 ? 31.610 47.986 -33.072 1.00 14.74 ? 902 CYS A N 1 ATOM 7292 C CA . CYS A 1 902 ? 32.380 47.718 -31.856 1.00 14.83 ? 902 CYS A CA 1 ATOM 7293 C C . CYS A 1 902 ? 31.849 46.495 -31.137 1.00 14.35 ? 902 CYS A C 1 ATOM 7294 O O . CYS A 1 902 ? 30.642 46.284 -31.056 1.00 15.49 ? 902 CYS A O 1 ATOM 7295 C CB . CYS A 1 902 ? 32.284 48.898 -30.894 1.00 15.13 ? 902 CYS A CB 1 ATOM 7296 S SG . CYS A 1 902 ? 33.075 50.398 -31.493 1.00 18.52 ? 902 CYS A SG 1 ATOM 7297 N N . VAL A 1 903 ? 32.750 45.716 -30.570 1.00 13.64 ? 903 VAL A N 1 ATOM 7298 C CA . VAL A 1 903 ? 32.333 44.600 -29.709 1.00 14.45 ? 903 VAL A CA 1 ATOM 7299 C C . VAL A 1 903 ? 32.046 45.156 -28.302 1.00 13.88 ? 903 VAL A C 1 ATOM 7300 O O . VAL A 1 903 ? 32.976 45.481 -27.534 1.00 15.41 ? 903 VAL A O 1 ATOM 7301 C CB . VAL A 1 903 ? 33.400 43.512 -29.675 1.00 13.92 ? 903 VAL A CB 1 ATOM 7302 C CG1 . VAL A 1 903 ? 33.011 42.386 -28.690 1.00 15.12 ? 903 VAL A CG1 1 ATOM 7303 C CG2 . VAL A 1 903 ? 33.600 42.966 -31.076 1.00 15.02 ? 903 VAL A CG2 1 ATOM 7304 N N . ARG A 1 904 ? 30.785 45.320 -27.979 1.00 13.66 ? 904 ARG A N 1 ATOM 7305 C CA . ARG A 1 904 ? 30.391 45.926 -26.725 1.00 13.47 ? 904 ARG A CA 1 ATOM 7306 C C . ARG A 1 904 ? 29.870 44.871 -25.775 1.00 13.80 ? 904 ARG A C 1 ATOM 7307 O O . ARG A 1 904 ? 29.483 43.771 -26.190 1.00 13.91 ? 904 ARG A O 1 ATOM 7308 C CB . ARG A 1 904 ? 29.318 46.983 -26.980 1.00 13.80 ? 904 ARG A CB 1 ATOM 7309 C CG . ARG A 1 904 ? 29.892 48.235 -27.628 1.00 14.80 ? 904 ARG A CG 1 ATOM 7310 C CD . ARG A 1 904 ? 28.880 49.326 -27.887 1.00 18.43 ? 904 ARG A CD 1 ATOM 7311 N NE . ARG A 1 904 ? 28.107 48.979 -29.068 1.00 18.14 ? 904 ARG A NE 1 ATOM 7312 C CZ . ARG A 1 904 ? 27.137 49.732 -29.551 1.00 20.08 ? 904 ARG A CZ 1 ATOM 7313 N NH1 . ARG A 1 904 ? 26.800 50.874 -28.951 1.00 19.13 ? 904 ARG A NH1 1 ATOM 7314 N NH2 . ARG A 1 904 ? 26.494 49.316 -30.640 1.00 21.34 ? 904 ARG A NH2 1 ATOM 7315 N N . PRO A 1 905 ? 29.829 45.190 -24.487 1.00 11.75 ? 905 PRO A N 1 ATOM 7316 C CA . PRO A 1 905 ? 29.216 44.261 -23.528 1.00 12.94 ? 905 PRO A CA 1 ATOM 7317 C C . PRO A 1 905 ? 27.760 44.039 -23.856 1.00 13.73 ? 905 PRO A C 1 ATOM 7318 O O . PRO A 1 905 ? 27.137 44.854 -24.526 1.00 13.47 ? 905 PRO A O 1 ATOM 7319 C CB . PRO A 1 905 ? 29.334 45.013 -22.196 1.00 11.84 ? 905 PRO A CB 1 ATOM 7320 C CG . PRO A 1 905 ? 30.507 45.955 -22.393 1.00 11.54 ? 905 PRO A CG 1 ATOM 7321 C CD . PRO A 1 905 ? 30.326 46.435 -23.828 1.00 11.97 ? 905 PRO A CD 1 ATOM 7322 N N . SER A 1 906 ? 27.214 42.935 -23.364 1.00 13.82 ? 906 SER A N 1 ATOM 7323 C CA . SER A 1 906 ? 25.795 42.688 -23.507 1.00 16.64 ? 906 SER A CA 1 ATOM 7324 C C . SER A 1 906 ? 24.955 43.704 -22.736 1.00 17.28 ? 906 SER A C 1 ATOM 7325 O O . SER A 1 906 ? 25.461 44.433 -21.855 1.00 16.53 ? 906 SER A O 1 ATOM 7326 C CB . SER A 1 906 ? 25.485 41.296 -23.004 1.00 18.66 ? 906 SER A CB 1 ATOM 7327 O OG . SER A 1 906 ? 25.215 41.363 -21.635 1.00 23.00 ? 906 SER A OG 1 ATOM 7328 N N . LYS A 1 907 ? 23.669 43.742 -23.051 1.00 17.20 ? 907 LYS A N 1 ATOM 7329 C CA . LYS A 1 907 ? 22.732 44.660 -22.415 1.00 19.72 ? 907 LYS A CA 1 ATOM 7330 C C . LYS A 1 907 ? 22.684 44.514 -20.885 1.00 18.50 ? 907 LYS A C 1 ATOM 7331 O O . LYS A 1 907 ? 22.324 45.467 -20.191 1.00 20.21 ? 907 LYS A O 1 ATOM 7332 C CB . LYS A 1 907 ? 21.333 44.504 -23.044 1.00 19.96 ? 907 LYS A CB 1 ATOM 7333 C CG . LYS A 1 907 ? 21.285 44.927 -24.526 1.00 24.08 ? 907 LYS A CG 1 ATOM 7334 C CD . LYS A 1 907 ? 19.948 44.567 -25.219 1.00 24.40 ? 907 LYS A CD 1 ATOM 7335 C CE . LYS A 1 907 ? 18.759 44.610 -24.251 1.00 31.05 ? 907 LYS A CE 1 ATOM 7336 N NZ . LYS A 1 907 ? 18.539 45.959 -23.631 1.00 33.00 ? 907 LYS A NZ 1 ATOM 7337 N N . LEU A 1 908 ? 23.047 43.351 -20.356 1.00 17.42 ? 908 LEU A N 1 ATOM 7338 C CA . LEU A 1 908 ? 22.968 43.154 -18.906 1.00 17.38 ? 908 LEU A CA 1 ATOM 7339 C C . LEU A 1 908 ? 24.277 43.478 -18.163 1.00 14.98 ? 908 LEU A C 1 ATOM 7340 O O . LEU A 1 908 ? 24.316 43.438 -16.933 1.00 16.61 ? 908 LEU A O 1 ATOM 7341 C CB . LEU A 1 908 ? 22.534 41.720 -18.565 1.00 18.77 ? 908 LEU A CB 1 ATOM 7342 C CG . LEU A 1 908 ? 21.158 41.251 -19.048 1.00 21.95 ? 908 LEU A CG 1 ATOM 7343 C CD1 . LEU A 1 908 ? 20.953 39.770 -18.721 1.00 23.87 ? 908 LEU A CD1 1 ATOM 7344 C CD2 . LEU A 1 908 ? 20.053 42.111 -18.440 1.00 23.94 ? 908 LEU A CD2 1 ATOM 7345 N N . HIS A 1 909 ? 25.356 43.730 -18.895 1.00 13.02 ? 909 HIS A N 1 ATOM 7346 C CA . HIS A 1 909 ? 26.634 44.040 -18.258 1.00 12.18 ? 909 HIS A CA 1 ATOM 7347 C C . HIS A 1 909 ? 26.589 45.431 -17.617 1.00 11.85 ? 909 HIS A C 1 ATOM 7348 O O . HIS A 1 909 ? 26.107 46.381 -18.222 1.00 12.04 ? 909 HIS A O 1 ATOM 7349 C CB . HIS A 1 909 ? 27.704 44.017 -19.296 1.00 12.53 ? 909 HIS A CB 1 ATOM 7350 C CG . HIS A 1 909 ? 29.064 43.768 -18.750 1.00 11.86 ? 909 HIS A CG 1 ATOM 7351 N ND1 . HIS A 1 909 ? 29.769 44.728 -18.036 1.00 12.96 ? 909 HIS A ND1 1 ATOM 7352 C CD2 . HIS A 1 909 ? 29.861 42.676 -18.807 1.00 11.84 ? 909 HIS A CD2 1 ATOM 7353 C CE1 . HIS A 1 909 ? 30.935 44.217 -17.682 1.00 11.87 ? 909 HIS A CE1 1 ATOM 7354 N NE2 . HIS A 1 909 ? 31.029 42.982 -18.163 1.00 12.37 ? 909 HIS A NE2 1 ATOM 7355 N N . PRO A 1 910 ? 27.055 45.561 -16.386 1.00 10.46 ? 910 PRO A N 1 ATOM 7356 C CA . PRO A 1 910 ? 27.009 46.869 -15.708 1.00 10.47 ? 910 PRO A CA 1 ATOM 7357 C C . PRO A 1 910 ? 28.131 47.853 -16.084 1.00 9.15 ? 910 PRO A C 1 ATOM 7358 O O . PRO A 1 910 ? 28.080 48.983 -15.537 1.00 9.23 ? 910 PRO A O 1 ATOM 7359 C CB . PRO A 1 910 ? 27.083 46.518 -14.218 1.00 11.53 ? 910 PRO A CB 1 ATOM 7360 C CG . PRO A 1 910 ? 27.140 45.036 -14.115 1.00 13.06 ? 910 PRO A CG 1 ATOM 7361 C CD . PRO A 1 910 ? 27.487 44.479 -15.475 1.00 12.06 ? 910 PRO A CD 1 ATOM 7362 N N . ALA A 1 911 ? 29.083 47.478 -16.926 1.00 9.25 ? 911 ALA A N 1 ATOM 7363 C CA . ALA A 1 911 ? 30.200 48.383 -17.287 1.00 9.75 ? 911 ALA A CA 1 ATOM 7364 C C . ALA A 1 911 ? 30.076 48.882 -18.701 1.00 9.48 ? 911 ALA A C 1 ATOM 7365 O O . ALA A 1 911 ? 29.371 48.274 -19.535 1.00 10.26 ? 911 ALA A O 1 ATOM 7366 C CB . ALA A 1 911 ? 31.536 47.655 -17.131 1.00 10.93 ? 911 ALA A CB 1 ATOM 7367 N N . GLY A 1 912 ? 30.811 49.945 -19.030 1.00 9.22 ? 912 GLY A N 1 ATOM 7368 C CA . GLY A 1 912 ? 31.083 50.315 -20.408 1.00 9.55 ? 912 GLY A CA 1 ATOM 7369 C C . GLY A 1 912 ? 32.552 50.626 -20.540 1.00 8.53 ? 912 GLY A C 1 ATOM 7370 O O . GLY A 1 912 ? 33.256 50.732 -19.519 1.00 9.28 ? 912 GLY A O 1 ATOM 7371 N N . TYR A 1 913 ? 33.030 50.789 -21.761 1.00 8.98 ? 913 TYR A N 1 ATOM 7372 C CA . TYR A 1 913 ? 34.443 50.964 -22.057 1.00 8.94 ? 913 TYR A CA 1 ATOM 7373 C C . TYR A 1 913 ? 34.609 52.004 -23.138 1.00 9.32 ? 913 TYR A C 1 ATOM 7374 O O . TYR A 1 913 ? 33.787 52.056 -24.082 1.00 10.01 ? 913 TYR A O 1 ATOM 7375 C CB . TYR A 1 913 ? 35.085 49.624 -22.517 1.00 9.74 ? 913 TYR A CB 1 ATOM 7376 C CG . TYR A 1 913 ? 35.023 48.591 -21.410 1.00 9.61 ? 913 TYR A CG 1 ATOM 7377 C CD1 . TYR A 1 913 ? 35.917 48.651 -20.354 1.00 9.97 ? 913 TYR A CD1 1 ATOM 7378 C CD2 . TYR A 1 913 ? 34.011 47.621 -21.377 1.00 10.64 ? 913 TYR A CD2 1 ATOM 7379 C CE1 . TYR A 1 913 ? 35.872 47.770 -19.325 1.00 10.06 ? 913 TYR A CE1 1 ATOM 7380 C CE2 . TYR A 1 913 ? 33.940 46.698 -20.322 1.00 10.98 ? 913 TYR A CE2 1 ATOM 7381 C CZ . TYR A 1 913 ? 34.880 46.803 -19.314 1.00 9.98 ? 913 TYR A CZ 1 ATOM 7382 O OH . TYR A 1 913 ? 34.788 45.951 -18.254 1.00 10.75 ? 913 TYR A OH 1 ATOM 7383 N N . LEU A 1 914 ? 35.673 52.788 -23.022 1.00 9.03 ? 914 LEU A N 1 ATOM 7384 C CA . LEU A 1 914 ? 35.987 53.779 -24.033 1.00 9.17 ? 914 LEU A CA 1 ATOM 7385 C C . LEU A 1 914 ? 36.533 53.155 -25.289 1.00 10.12 ? 914 LEU A C 1 ATOM 7386 O O . LEU A 1 914 ? 37.073 52.045 -25.293 1.00 10.63 ? 914 LEU A O 1 ATOM 7387 C CB . LEU A 1 914 ? 37.058 54.738 -23.472 1.00 9.62 ? 914 LEU A CB 1 ATOM 7388 C CG . LEU A 1 914 ? 36.604 55.627 -22.322 1.00 9.64 ? 914 LEU A CG 1 ATOM 7389 C CD1 . LEU A 1 914 ? 37.733 56.635 -22.000 1.00 10.27 ? 914 LEU A CD1 1 ATOM 7390 C CD2 . LEU A 1 914 ? 35.323 56.400 -22.624 1.00 10.39 ? 914 LEU A CD2 1 ATOM 7391 N N . THR A 1 915 ? 36.400 53.896 -26.391 1.00 10.70 ? 915 THR A N 1 ATOM 7392 C CA . THR A 1 915 ? 37.185 53.625 -27.586 1.00 10.70 ? 915 THR A CA 1 ATOM 7393 C C . THR A 1 915 ? 38.609 54.156 -27.457 1.00 11.21 ? 915 THR A C 1 ATOM 7394 O O . THR A 1 915 ? 38.881 55.020 -26.574 1.00 11.36 ? 915 THR A O 1 ATOM 7395 C CB . THR A 1 915 ? 36.554 54.321 -28.789 1.00 12.02 ? 915 THR A CB 1 ATOM 7396 O OG1 . THR A 1 915 ? 36.510 55.736 -28.505 1.00 13.57 ? 915 THR A OG1 1 ATOM 7397 C CG2 . THR A 1 915 ? 35.105 53.844 -29.038 1.00 13.33 ? 915 THR A CG2 1 ATOM 7398 N N . SER A 1 916 ? 39.508 53.737 -28.332 1.00 11.32 ? 916 SER A N 1 ATOM 7399 C CA . SER A 1 916 ? 40.832 54.299 -28.403 1.00 12.42 ? 916 SER A CA 1 ATOM 7400 C C . SER A 1 916 ? 40.840 55.826 -28.497 1.00 11.61 ? 916 SER A C 1 ATOM 7401 O O . SER A 1 916 ? 41.577 56.491 -27.764 1.00 11.30 ? 916 SER A O 1 ATOM 7402 C CB . SER A 1 916 ? 41.575 53.734 -29.613 1.00 13.01 ? 916 SER A CB 1 ATOM 7403 O OG . SER A 1 916 ? 42.793 54.410 -29.827 1.00 20.39 ? 916 SER A OG 1 ATOM 7404 N N . ALA A 1 917 ? 40.012 56.398 -29.362 1.00 10.89 ? 917 ALA A N 1 ATOM 7405 C CA . ALA A 1 917 ? 40.049 57.845 -29.545 1.00 10.96 ? 917 ALA A CA 1 ATOM 7406 C C . ALA A 1 917 ? 39.646 58.558 -28.278 1.00 10.40 ? 917 ALA A C 1 ATOM 7407 O O . ALA A 1 917 ? 40.226 59.595 -27.942 1.00 10.09 ? 917 ALA A O 1 ATOM 7408 C CB . ALA A 1 917 ? 39.132 58.278 -30.686 1.00 11.68 ? 917 ALA A CB 1 ATOM 7409 N N . ALA A 1 918 ? 38.632 58.052 -27.589 1.00 9.35 ? 918 ALA A N 1 ATOM 7410 C CA . ALA A 1 918 ? 38.164 58.707 -26.364 1.00 9.29 ? 918 ALA A CA 1 ATOM 7411 C C . ALA A 1 918 ? 39.188 58.591 -25.247 1.00 8.62 ? 918 ALA A C 1 ATOM 7412 O O . ALA A 1 918 ? 39.398 59.552 -24.487 1.00 8.88 ? 918 ALA A O 1 ATOM 7413 C CB . ALA A 1 918 ? 36.802 58.192 -25.946 1.00 9.84 ? 918 ALA A CB 1 ATOM 7414 N N . HIS A 1 919 ? 39.833 57.453 -25.147 1.00 7.77 ? 919 HIS A N 1 ATOM 7415 C CA . HIS A 1 919 ? 40.848 57.266 -24.126 1.00 8.28 ? 919 HIS A CA 1 ATOM 7416 C C . HIS A 1 919 ? 42.025 58.199 -24.391 1.00 8.53 ? 919 HIS A C 1 ATOM 7417 O O . HIS A 1 919 ? 42.520 58.833 -23.485 1.00 8.61 ? 919 HIS A O 1 ATOM 7418 C CB . HIS A 1 919 ? 41.300 55.806 -24.122 1.00 9.33 ? 919 HIS A CB 1 ATOM 7419 C CG . HIS A 1 919 ? 42.486 55.544 -23.254 1.00 10.00 ? 919 HIS A CG 1 ATOM 7420 N ND1 . HIS A 1 919 ? 42.452 55.640 -21.883 1.00 14.07 ? 919 HIS A ND1 1 ATOM 7421 C CD2 . HIS A 1 919 ? 43.746 55.195 -23.580 1.00 11.97 ? 919 HIS A CD2 1 ATOM 7422 C CE1 . HIS A 1 919 ? 43.649 55.349 -21.404 1.00 13.04 ? 919 HIS A CE1 1 ATOM 7423 N NE2 . HIS A 1 919 ? 44.446 55.061 -22.411 1.00 12.79 ? 919 HIS A NE2 1 ATOM 7424 N N . LYS A 1 920 ? 42.473 58.278 -25.634 1.00 9.10 ? 920 LYS A N 1 ATOM 7425 C CA . LYS A 1 920 ? 43.546 59.218 -25.966 1.00 10.03 ? 920 LYS A CA 1 ATOM 7426 C C . LYS A 1 920 ? 43.157 60.668 -25.690 1.00 8.58 ? 920 LYS A C 1 ATOM 7427 O O . LYS A 1 920 ? 43.993 61.449 -25.229 1.00 9.00 ? 920 LYS A O 1 ATOM 7428 C CB . LYS A 1 920 ? 44.011 59.046 -27.397 1.00 12.27 ? 920 LYS A CB 1 ATOM 7429 C CG . LYS A 1 920 ? 44.823 57.784 -27.554 1.00 15.96 ? 920 LYS A CG 1 ATOM 7430 C CD . LYS A 1 920 ? 45.615 57.771 -28.864 1.00 20.64 ? 920 LYS A CD 1 ATOM 7431 C CE . LYS A 1 920 ? 46.514 56.546 -28.947 1.00 22.17 ? 920 LYS A CE 1 ATOM 7432 N NZ . LYS A 1 920 ? 47.719 56.639 -28.060 1.00 20.08 ? 920 LYS A NZ 1 ATOM 7433 N N . ALA A 1 921 ? 41.912 61.023 -25.975 1.00 8.23 ? 921 ALA A N 1 ATOM 7434 C CA . ALA A 1 921 ? 41.454 62.365 -25.689 1.00 8.86 ? 921 ALA A CA 1 ATOM 7435 C C . ALA A 1 921 ? 41.489 62.638 -24.170 1.00 8.26 ? 921 ALA A C 1 ATOM 7436 O O . ALA A 1 921 ? 41.858 63.724 -23.743 1.00 8.53 ? 921 ALA A O 1 ATOM 7437 C CB . ALA A 1 921 ? 40.038 62.531 -26.259 1.00 8.28 ? 921 ALA A CB 1 ATOM 7438 N N . SER A 1 922 ? 41.095 61.654 -23.364 1.00 8.01 ? 922 SER A N 1 ATOM 7439 C CA . SER A 1 922 ? 41.199 61.816 -21.909 1.00 7.57 ? 922 SER A CA 1 ATOM 7440 C C . SER A 1 922 ? 42.662 62.001 -21.494 1.00 7.95 ? 922 SER A C 1 ATOM 7441 O O . SER A 1 922 ? 42.967 62.881 -20.681 1.00 8.39 ? 922 SER A O 1 ATOM 7442 C CB . SER A 1 922 ? 40.583 60.588 -21.216 1.00 8.31 ? 922 SER A CB 1 ATOM 7443 O OG . SER A 1 922 ? 40.748 60.737 -19.807 1.00 8.31 ? 922 SER A OG 1 ATOM 7444 N N . GLN A 1 923 ? 43.576 61.239 -22.069 1.00 7.80 ? 923 GLN A N 1 ATOM 7445 C CA . GLN A 1 923 ? 45.007 61.396 -21.743 1.00 8.44 ? 923 GLN A CA 1 ATOM 7446 C C . GLN A 1 923 ? 45.502 62.783 -22.152 1.00 8.66 ? 923 GLN A C 1 ATOM 7447 O O . GLN A 1 923 ? 46.348 63.372 -21.473 1.00 8.63 ? 923 GLN A O 1 ATOM 7448 C CB . GLN A 1 923 ? 45.844 60.329 -22.445 1.00 8.55 ? 923 GLN A CB 1 ATOM 7449 C CG . GLN A 1 923 ? 45.548 58.925 -21.901 1.00 9.40 ? 923 GLN A CG 1 ATOM 7450 C CD . GLN A 1 923 ? 46.501 57.900 -22.474 1.00 11.14 ? 923 GLN A CD 1 ATOM 7451 O OE1 . GLN A 1 923 ? 46.671 57.844 -23.707 1.00 11.36 ? 923 GLN A OE1 1 ATOM 7452 N NE2 . GLN A 1 923 ? 47.130 57.086 -21.608 1.00 9.94 ? 923 GLN A NE2 1 ATOM 7453 N N A SER A 1 924 ? 44.987 63.309 -23.263 0.50 8.93 ? 924 SER A N 1 ATOM 7454 N N B SER A 1 924 ? 44.992 63.331 -23.253 0.50 8.90 ? 924 SER A N 1 ATOM 7455 C CA A SER A 1 924 ? 45.371 64.643 -23.714 0.50 9.32 ? 924 SER A CA 1 ATOM 7456 C CA B SER A 1 924 ? 45.411 64.667 -23.686 0.50 9.20 ? 924 SER A CA 1 ATOM 7457 C C A SER A 1 924 ? 45.027 65.690 -22.651 0.50 9.19 ? 924 SER A C 1 ATOM 7458 C C B SER A 1 924 ? 44.954 65.767 -22.723 0.50 8.99 ? 924 SER A C 1 ATOM 7459 O O A SER A 1 924 ? 45.781 66.652 -22.445 0.50 9.80 ? 924 SER A O 1 ATOM 7460 O O B SER A 1 924 ? 45.531 66.860 -22.677 0.50 9.29 ? 924 SER A O 1 ATOM 7461 C CB A SER A 1 924 ? 44.678 64.988 -25.039 0.50 9.81 ? 924 SER A CB 1 ATOM 7462 C CB B SER A 1 924 ? 44.867 64.961 -25.074 0.50 9.94 ? 924 SER A CB 1 ATOM 7463 O OG A SER A 1 924 ? 43.359 65.472 -24.859 0.50 10.65 ? 924 SER A OG 1 ATOM 7464 O OG B SER A 1 924 ? 45.498 64.128 -26.022 0.50 10.27 ? 924 SER A OG 1 ATOM 7465 N N . LEU A 1 925 ? 43.903 65.493 -21.968 1.00 8.80 ? 925 LEU A N 1 ATOM 7466 C CA . LEU A 1 925 ? 43.438 66.437 -20.963 1.00 8.57 ? 925 LEU A CA 1 ATOM 7467 C C . LEU A 1 925 ? 44.213 66.265 -19.666 1.00 9.08 ? 925 LEU A C 1 ATOM 7468 O O . LEU A 1 925 ? 44.567 67.252 -19.039 1.00 10.56 ? 925 LEU A O 1 ATOM 7469 C CB . LEU A 1 925 ? 41.942 66.253 -20.676 1.00 8.42 ? 925 LEU A CB 1 ATOM 7470 C CG . LEU A 1 925 ? 41.020 66.546 -21.861 1.00 7.27 ? 925 LEU A CG 1 ATOM 7471 C CD1 . LEU A 1 925 ? 39.584 66.278 -21.402 1.00 9.59 ? 925 LEU A CD1 1 ATOM 7472 C CD2 . LEU A 1 925 ? 41.182 68.012 -22.321 1.00 10.28 ? 925 LEU A CD2 1 ATOM 7473 N N . LEU A 1 926 ? 44.412 65.023 -19.231 1.00 8.14 ? 926 LEU A N 1 ATOM 7474 C CA . LEU A 1 926 ? 44.965 64.789 -17.889 1.00 8.10 ? 926 LEU A CA 1 ATOM 7475 C C . LEU A 1 926 ? 46.467 64.756 -17.865 1.00 8.38 ? 926 LEU A C 1 ATOM 7476 O O . LEU A 1 926 ? 47.063 65.166 -16.842 1.00 8.79 ? 926 LEU A O 1 ATOM 7477 C CB . LEU A 1 926 ? 44.371 63.514 -17.298 1.00 9.71 ? 926 LEU A CB 1 ATOM 7478 C CG . LEU A 1 926 ? 42.854 63.595 -17.058 1.00 11.45 ? 926 LEU A CG 1 ATOM 7479 C CD1 . LEU A 1 926 ? 42.382 62.251 -16.485 1.00 13.42 ? 926 LEU A CD1 1 ATOM 7480 C CD2 . LEU A 1 926 ? 42.511 64.761 -16.114 1.00 13.62 ? 926 LEU A CD2 1 ATOM 7481 N N . ASP A 1 927 ? 47.101 64.293 -18.927 1.00 7.28 ? 927 ASP A N 1 ATOM 7482 C CA . ASP A 1 927 ? 48.553 64.230 -18.932 1.00 8.26 ? 927 ASP A CA 1 ATOM 7483 C C . ASP A 1 927 ? 49.097 64.756 -20.249 1.00 7.90 ? 927 ASP A C 1 ATOM 7484 O O . ASP A 1 927 ? 49.662 64.012 -21.049 1.00 8.04 ? 927 ASP A O 1 ATOM 7485 C CB . ASP A 1 927 ? 49.037 62.815 -18.678 1.00 9.05 ? 927 ASP A CB 1 ATOM 7486 C CG . ASP A 1 927 ? 48.696 62.341 -17.270 1.00 9.58 ? 927 ASP A CG 1 ATOM 7487 O OD1 . ASP A 1 927 ? 49.421 62.716 -16.297 1.00 10.32 ? 927 ASP A OD1 1 ATOM 7488 O OD2 . ASP A 1 927 ? 47.712 61.600 -17.088 1.00 10.66 ? 927 ASP A OD2 1 ATOM 7489 N N . PRO A 1 928 ? 48.945 66.065 -20.461 1.00 8.33 ? 928 PRO A N 1 ATOM 7490 C CA . PRO A 1 928 ? 49.453 66.706 -21.685 1.00 8.51 ? 928 PRO A CA 1 ATOM 7491 C C . PRO A 1 928 ? 50.974 66.695 -21.672 1.00 8.58 ? 928 PRO A C 1 ATOM 7492 O O . PRO A 1 928 ? 51.617 66.451 -20.633 1.00 8.79 ? 928 PRO A O 1 ATOM 7493 C CB . PRO A 1 928 ? 48.945 68.154 -21.551 1.00 10.35 ? 928 PRO A CB 1 ATOM 7494 C CG . PRO A 1 928 ? 48.915 68.372 -20.082 1.00 11.87 ? 928 PRO A CG 1 ATOM 7495 C CD . PRO A 1 928 ? 48.365 67.044 -19.522 1.00 9.60 ? 928 PRO A CD 1 ATOM 7496 N N . LEU A 1 929 ? 51.604 67.042 -22.791 1.00 8.26 ? 929 LEU A N 1 ATOM 7497 C CA . LEU A 1 929 ? 53.025 67.348 -22.787 1.00 8.43 ? 929 LEU A CA 1 ATOM 7498 C C . LEU A 1 929 ? 53.316 68.515 -21.878 1.00 8.56 ? 929 LEU A C 1 ATOM 7499 O O . LEU A 1 929 ? 52.539 69.475 -21.816 1.00 10.37 ? 929 LEU A O 1 ATOM 7500 C CB . LEU A 1 929 ? 53.502 67.695 -24.205 1.00 8.75 ? 929 LEU A CB 1 ATOM 7501 C CG . LEU A 1 929 ? 53.312 66.664 -25.308 1.00 9.10 ? 929 LEU A CG 1 ATOM 7502 C CD1 . LEU A 1 929 ? 53.875 67.241 -26.613 1.00 11.08 ? 929 LEU A CD1 1 ATOM 7503 C CD2 . LEU A 1 929 ? 54.057 65.367 -24.964 1.00 9.32 ? 929 LEU A CD2 1 ATOM 7504 N N . ASP A 1 930 ? 54.437 68.442 -21.167 1.00 8.19 ? 930 ASP A N 1 ATOM 7505 C CA . ASP A 1 930 ? 54.911 69.564 -20.367 1.00 8.28 ? 930 ASP A CA 1 ATOM 7506 C C . ASP A 1 930 ? 55.927 70.401 -21.137 1.00 8.61 ? 930 ASP A C 1 ATOM 7507 O O . ASP A 1 930 ? 56.806 69.863 -21.811 1.00 10.07 ? 930 ASP A O 1 ATOM 7508 C CB . ASP A 1 930 ? 55.525 69.067 -19.057 1.00 8.58 ? 930 ASP A CB 1 ATOM 7509 C CG . ASP A 1 930 ? 54.701 67.973 -18.406 1.00 10.17 ? 930 ASP A CG 1 ATOM 7510 O OD1 . ASP A 1 930 ? 53.601 68.277 -17.899 1.00 12.15 ? 930 ASP A OD1 1 ATOM 7511 O OD2 . ASP A 1 930 ? 55.154 66.809 -18.402 1.00 9.94 ? 930 ASP A OD2 1 ATOM 7512 N N . LYS A 1 931 ? 55.800 71.720 -21.033 1.00 8.77 ? 931 LYS A N 1 ATOM 7513 C CA . LYS A 1 931 ? 56.607 72.640 -21.844 1.00 9.05 ? 931 LYS A CA 1 ATOM 7514 C C . LYS A 1 931 ? 57.538 73.435 -20.978 1.00 9.26 ? 931 LYS A C 1 ATOM 7515 O O . LYS A 1 931 ? 57.102 74.044 -19.983 1.00 10.08 ? 931 LYS A O 1 ATOM 7516 C CB . LYS A 1 931 ? 55.685 73.598 -22.619 1.00 10.05 ? 931 LYS A CB 1 ATOM 7517 C CG . LYS A 1 931 ? 54.703 72.934 -23.579 1.00 12.29 ? 931 LYS A CG 1 ATOM 7518 C CD . LYS A 1 931 ? 53.806 73.980 -24.248 1.00 14.14 ? 931 LYS A CD 1 ATOM 7519 C CE . LYS A 1 931 ? 52.769 74.511 -23.283 1.00 17.66 ? 931 LYS A CE 1 ATOM 7520 N NZ . LYS A 1 931 ? 52.098 75.702 -23.806 1.00 18.09 ? 931 LYS A NZ 1 ATOM 7521 N N . PHE A 1 932 ? 58.811 73.482 -21.364 1.00 8.31 ? 932 PHE A N 1 ATOM 7522 C CA . PHE A 1 932 ? 59.858 74.179 -20.610 1.00 8.36 ? 932 PHE A CA 1 ATOM 7523 C C . PHE A 1 932 ? 60.517 75.212 -21.518 1.00 8.13 ? 932 PHE A C 1 ATOM 7524 O O . PHE A 1 932 ? 60.833 74.901 -22.671 1.00 9.64 ? 932 PHE A O 1 ATOM 7525 C CB . PHE A 1 932 ? 60.936 73.199 -20.160 1.00 8.36 ? 932 PHE A CB 1 ATOM 7526 C CG . PHE A 1 932 ? 60.444 72.112 -19.251 1.00 8.60 ? 932 PHE A CG 1 ATOM 7527 C CD1 . PHE A 1 932 ? 59.838 70.969 -19.758 1.00 9.80 ? 932 PHE A CD1 1 ATOM 7528 C CD2 . PHE A 1 932 ? 60.593 72.247 -17.867 1.00 10.90 ? 932 PHE A CD2 1 ATOM 7529 C CE1 . PHE A 1 932 ? 59.405 69.920 -18.889 1.00 9.23 ? 932 PHE A CE1 1 ATOM 7530 C CE2 . PHE A 1 932 ? 60.156 71.217 -17.004 1.00 11.10 ? 932 PHE A CE2 1 ATOM 7531 C CZ . PHE A 1 932 ? 59.551 70.075 -17.527 1.00 10.57 ? 932 PHE A CZ 1 ATOM 7532 N N . ILE A 1 933 ? 60.731 76.409 -21.004 1.00 8.33 ? 933 ILE A N 1 ATOM 7533 C CA . ILE A 1 933 ? 61.401 77.481 -21.756 1.00 8.82 ? 933 ILE A CA 1 ATOM 7534 C C . ILE A 1 933 ? 62.738 77.721 -21.091 1.00 9.71 ? 933 ILE A C 1 ATOM 7535 O O . ILE A 1 933 ? 62.791 78.010 -19.894 1.00 8.98 ? 933 ILE A O 1 ATOM 7536 C CB . ILE A 1 933 ? 60.590 78.786 -21.712 1.00 9.05 ? 933 ILE A CB 1 ATOM 7537 C CG1 . ILE A 1 933 ? 59.182 78.574 -22.280 1.00 9.53 ? 933 ILE A CG1 1 ATOM 7538 C CG2 . ILE A 1 933 ? 61.330 79.889 -22.479 1.00 10.36 ? 933 ILE A CG2 1 ATOM 7539 C CD1 . ILE A 1 933 ? 58.256 79.740 -22.033 1.00 11.09 ? 933 ILE A CD1 1 ATOM 7540 N N . PHE A 1 934 ? 63.836 77.608 -21.847 1.00 9.80 ? 934 PHE A N 1 ATOM 7541 C CA . PHE A 1 934 ? 65.148 77.814 -21.236 1.00 10.57 ? 934 PHE A CA 1 ATOM 7542 C C . PHE A 1 934 ? 65.274 79.281 -20.777 1.00 10.93 ? 934 PHE A C 1 ATOM 7543 O O . PHE A 1 934 ? 64.946 80.201 -21.514 1.00 11.79 ? 934 PHE A O 1 ATOM 7544 C CB . PHE A 1 934 ? 66.257 77.445 -22.228 1.00 11.24 ? 934 PHE A CB 1 ATOM 7545 C CG . PHE A 1 934 ? 67.618 77.490 -21.623 1.00 12.40 ? 934 PHE A CG 1 ATOM 7546 C CD1 . PHE A 1 934 ? 68.026 76.492 -20.759 1.00 13.13 ? 934 PHE A CD1 1 ATOM 7547 C CD2 . PHE A 1 934 ? 68.477 78.568 -21.871 1.00 13.79 ? 934 PHE A CD2 1 ATOM 7548 C CE1 . PHE A 1 934 ? 69.304 76.523 -20.165 1.00 15.98 ? 934 PHE A CE1 1 ATOM 7549 C CE2 . PHE A 1 934 ? 69.740 78.620 -21.289 1.00 15.26 ? 934 PHE A CE2 1 ATOM 7550 C CZ . PHE A 1 934 ? 70.160 77.613 -20.436 1.00 17.06 ? 934 PHE A CZ 1 ATOM 7551 N N . ALA A 1 935 ? 65.716 79.495 -19.538 1.00 11.87 ? 935 ALA A N 1 ATOM 7552 C CA . ALA A 1 935 ? 65.647 80.822 -18.953 1.00 14.16 ? 935 ALA A CA 1 ATOM 7553 C C . ALA A 1 935 ? 66.768 81.756 -19.421 1.00 16.45 ? 935 ALA A C 1 ATOM 7554 O O . ALA A 1 935 ? 66.517 82.959 -19.669 1.00 19.01 ? 935 ALA A O 1 ATOM 7555 C CB . ALA A 1 935 ? 65.659 80.716 -17.446 1.00 15.99 ? 935 ALA A CB 1 ATOM 7556 N N . GLU A 1 936 ? 67.983 81.237 -19.551 1.00 15.60 ? 936 GLU A N 1 ATOM 7557 C CA A GLU A 1 936 ? 69.201 82.002 -19.873 0.50 16.31 ? 936 GLU A CA 1 ATOM 7558 C CA B GLU A 1 936 ? 69.088 82.132 -19.865 0.50 16.34 ? 936 GLU A CA 1 ATOM 7559 C C . GLU A 1 936 ? 69.297 82.255 -21.370 1.00 16.11 ? 936 GLU A C 1 ATOM 7560 O O . GLU A 1 936 ? 68.542 81.687 -22.168 1.00 16.33 ? 936 GLU A O 1 ATOM 7561 C CB A GLU A 1 936 ? 70.459 81.216 -19.438 0.50 15.90 ? 936 GLU A CB 1 ATOM 7562 C CB B GLU A 1 936 ? 70.337 81.721 -19.090 0.50 16.90 ? 936 GLU A CB 1 ATOM 7563 C CG A GLU A 1 936 ? 70.672 81.026 -17.932 0.50 17.53 ? 936 GLU A CG 1 ATOM 7564 C CG B GLU A 1 936 ? 70.169 81.893 -17.580 0.50 19.39 ? 936 GLU A CG 1 ATOM 7565 C CD A GLU A 1 936 ? 71.715 79.956 -17.596 0.50 18.15 ? 936 GLU A CD 1 ATOM 7566 C CD B GLU A 1 936 ? 69.832 83.320 -17.172 0.50 23.39 ? 936 GLU A CD 1 ATOM 7567 O OE1 A GLU A 1 936 ? 71.478 78.755 -17.862 0.50 19.09 ? 936 GLU A OE1 1 ATOM 7568 O OE1 B GLU A 1 936 ? 70.511 84.256 -17.647 0.50 24.55 ? 936 GLU A OE1 1 ATOM 7569 O OE2 A GLU A 1 936 ? 72.781 80.307 -17.044 0.50 21.23 ? 936 GLU A OE2 1 ATOM 7570 O OE2 B GLU A 1 936 ? 68.887 83.513 -16.371 0.50 26.56 ? 936 GLU A OE2 1 ATOM 7571 N N . ASN A 1 937 ? 70.276 83.057 -21.778 1.00 16.17 ? 937 ASN A N 1 ATOM 7572 C CA . ASN A 1 937 ? 70.432 83.318 -23.200 1.00 16.27 ? 937 ASN A CA 1 ATOM 7573 C C . ASN A 1 937 ? 70.961 82.149 -24.016 1.00 15.89 ? 937 ASN A C 1 ATOM 7574 O O . ASN A 1 937 ? 70.535 81.931 -25.158 1.00 15.45 ? 937 ASN A O 1 ATOM 7575 C CB . ASN A 1 937 ? 71.297 84.563 -23.415 1.00 16.45 ? 937 ASN A CB 1 ATOM 7576 C CG . ASN A 1 937 ? 70.549 85.855 -23.089 1.00 18.86 ? 937 ASN A CG 1 ATOM 7577 O OD1 . ASN A 1 937 ? 69.313 85.879 -22.970 1.00 20.13 ? 937 ASN A OD1 1 ATOM 7578 N ND2 . ASN A 1 937 ? 71.299 86.938 -22.945 1.00 23.15 ? 937 ASN A ND2 1 ATOM 7579 N N . GLU A 1 938 ? 71.888 81.397 -23.430 1.00 16.07 ? 938 GLU A N 1 ATOM 7580 C CA . GLU A 1 938 ? 72.510 80.298 -24.145 1.00 18.18 ? 938 GLU A CA 1 ATOM 7581 C C . GLU A 1 938 ? 72.602 79.054 -23.284 1.00 17.07 ? 938 GLU A C 1 ATOM 7582 O O . GLU A 1 938 ? 73.011 79.121 -22.149 1.00 17.55 ? 938 GLU A O 1 ATOM 7583 C CB . GLU A 1 938 ? 73.912 80.670 -24.621 1.00 19.59 ? 938 GLU A CB 1 ATOM 7584 C CG . GLU A 1 938 ? 74.502 79.587 -25.509 1.00 24.01 ? 938 GLU A CG 1 ATOM 7585 C CD . GLU A 1 938 ? 75.795 79.995 -26.182 1.00 30.71 ? 938 GLU A CD 1 ATOM 7586 O OE1 . GLU A 1 938 ? 76.365 81.046 -25.816 1.00 34.00 ? 938 GLU A OE1 1 ATOM 7587 O OE2 . GLU A 1 938 ? 76.234 79.245 -27.085 1.00 34.87 ? 938 GLU A OE2 1 ATOM 7588 N N . TRP A 1 939 ? 72.211 77.928 -23.859 1.00 17.46 ? 939 TRP A N 1 ATOM 7589 C CA . TRP A 1 939 ? 72.305 76.641 -23.173 1.00 16.98 ? 939 TRP A CA 1 ATOM 7590 C C . TRP A 1 939 ? 73.500 75.850 -23.715 1.00 17.62 ? 939 TRP A C 1 ATOM 7591 O O . TRP A 1 939 ? 73.412 75.221 -24.761 1.00 19.27 ? 939 TRP A O 1 ATOM 7592 C CB . TRP A 1 939 ? 70.978 75.904 -23.371 1.00 15.80 ? 939 TRP A CB 1 ATOM 7593 C CG . TRP A 1 939 ? 70.867 74.531 -22.765 1.00 13.44 ? 939 TRP A CG 1 ATOM 7594 C CD1 . TRP A 1 939 ? 71.746 73.892 -21.921 1.00 14.37 ? 939 TRP A CD1 1 ATOM 7595 C CD2 . TRP A 1 939 ? 69.768 73.647 -22.949 1.00 12.78 ? 939 TRP A CD2 1 ATOM 7596 N NE1 . TRP A 1 939 ? 71.259 72.647 -21.594 1.00 13.03 ? 939 TRP A NE1 1 ATOM 7597 C CE2 . TRP A 1 939 ? 70.058 72.459 -22.236 1.00 11.93 ? 939 TRP A CE2 1 ATOM 7598 C CE3 . TRP A 1 939 ? 68.582 73.712 -23.704 1.00 11.26 ? 939 TRP A CE3 1 ATOM 7599 C CZ2 . TRP A 1 939 ? 69.172 71.378 -22.199 1.00 13.02 ? 939 TRP A CZ2 1 ATOM 7600 C CZ3 . TRP A 1 939 ? 67.712 72.626 -23.692 1.00 13.31 ? 939 TRP A CZ3 1 ATOM 7601 C CH2 . TRP A 1 939 ? 68.024 71.465 -22.962 1.00 12.57 ? 939 TRP A CH2 1 ATOM 7602 N N . ILE A 1 940 ? 74.608 75.896 -22.987 1.00 19.89 ? 940 ILE A N 1 ATOM 7603 C CA . ILE A 1 940 ? 75.813 75.185 -23.430 1.00 21.09 ? 940 ILE A CA 1 ATOM 7604 C C . ILE A 1 940 ? 75.665 73.668 -23.181 1.00 19.27 ? 940 ILE A C 1 ATOM 7605 O O . ILE A 1 940 ? 75.242 73.256 -22.107 1.00 19.71 ? 940 ILE A O 1 ATOM 7606 C CB . ILE A 1 940 ? 77.068 75.762 -22.742 1.00 21.57 ? 940 ILE A CB 1 ATOM 7607 C CG1 . ILE A 1 940 ? 77.193 77.265 -23.048 1.00 22.60 ? 940 ILE A CG1 1 ATOM 7608 C CG2 . ILE A 1 940 ? 78.336 74.969 -23.148 1.00 22.71 ? 940 ILE A CG2 1 ATOM 7609 C CD1 . ILE A 1 940 ? 78.563 77.864 -22.742 1.00 24.06 ? 940 ILE A CD1 1 ATOM 7610 N N . GLY A 1 941 ? 75.986 72.857 -24.181 1.00 19.24 ? 941 GLY A N 1 ATOM 7611 C CA . GLY A 1 941 ? 75.923 71.414 -24.038 1.00 18.48 ? 941 GLY A CA 1 ATOM 7612 C C . GLY A 1 941 ? 74.526 70.829 -24.220 1.00 18.01 ? 941 GLY A C 1 ATOM 7613 O O . GLY A 1 941 ? 74.301 69.662 -23.901 1.00 16.74 ? 941 GLY A O 1 ATOM 7614 N N . ALA A 1 942 ? 73.607 71.611 -24.787 1.00 16.97 ? 942 ALA A N 1 ATOM 7615 C CA . ALA A 1 942 ? 72.225 71.165 -25.002 1.00 17.31 ? 942 ALA A CA 1 ATOM 7616 C C . ALA A 1 942 ? 72.146 69.966 -25.919 1.00 17.50 ? 942 ALA A C 1 ATOM 7617 O O . ALA A 1 942 ? 72.851 69.906 -26.935 1.00 18.52 ? 942 ALA A O 1 ATOM 7618 C CB . ALA A 1 942 ? 71.393 72.307 -25.565 1.00 17.31 ? 942 ALA A CB 1 ATOM 7619 N N . GLN A 1 943 ? 71.266 69.022 -25.590 1.00 16.14 ? 943 GLN A N 1 ATOM 7620 C CA . GLN A 1 943 ? 70.995 67.844 -26.393 1.00 17.22 ? 943 GLN A CA 1 ATOM 7621 C C . GLN A 1 943 ? 69.566 67.853 -26.915 1.00 14.91 ? 943 GLN A C 1 ATOM 7622 O O . GLN A 1 943 ? 68.675 68.507 -26.315 1.00 15.89 ? 943 GLN A O 1 ATOM 7623 C CB . GLN A 1 943 ? 71.223 66.548 -25.584 1.00 17.69 ? 943 GLN A CB 1 ATOM 7624 C CG . GLN A 1 943 ? 72.619 66.461 -25.008 1.00 21.57 ? 943 GLN A CG 1 ATOM 7625 C CD . GLN A 1 943 ? 72.800 65.285 -24.063 1.00 22.36 ? 943 GLN A CD 1 ATOM 7626 O OE1 . GLN A 1 943 ? 71.843 64.851 -23.397 1.00 27.80 ? 943 GLN A OE1 1 ATOM 7627 N NE2 . GLN A 1 943 ? 74.031 64.773 -23.987 1.00 27.46 ? 943 GLN A NE2 1 ATOM 7628 N N . GLY A 1 944 ? 69.310 67.128 -27.992 1.00 14.42 ? 944 GLY A N 1 ATOM 7629 C CA . GLY A 1 944 ? 68.063 67.245 -28.709 1.00 14.79 ? 944 GLY A CA 1 ATOM 7630 C C . GLY A 1 944 ? 66.957 66.340 -28.220 1.00 14.76 ? 944 GLY A C 1 ATOM 7631 O O . GLY A 1 944 ? 65.787 66.571 -28.509 1.00 14.41 ? 944 GLY A O 1 ATOM 7632 N N . GLN A 1 945 ? 67.309 65.287 -27.496 1.00 13.65 ? 945 GLN A N 1 ATOM 7633 C CA . GLN A 1 945 ? 66.297 64.275 -27.151 1.00 14.23 ? 945 GLN A CA 1 ATOM 7634 C C . GLN A 1 945 ? 66.770 63.436 -25.976 1.00 13.26 ? 945 GLN A C 1 ATOM 7635 O O . GLN A 1 945 ? 67.975 63.263 -25.744 1.00 14.00 ? 945 GLN A O 1 ATOM 7636 C CB . GLN A 1 945 ? 66.060 63.374 -28.361 1.00 14.14 ? 945 GLN A CB 1 ATOM 7637 C CG . GLN A 1 945 ? 64.842 62.476 -28.329 1.00 16.27 ? 945 GLN A CG 1 ATOM 7638 C CD . GLN A 1 945 ? 64.766 61.550 -29.548 1.00 16.92 ? 945 GLN A CD 1 ATOM 7639 O OE1 . GLN A 1 945 ? 63.908 61.723 -30.417 1.00 20.86 ? 945 GLN A OE1 1 ATOM 7640 N NE2 . GLN A 1 945 ? 65.639 60.563 -29.596 1.00 19.33 ? 945 GLN A NE2 1 ATOM 7641 N N . PHE A 1 946 ? 65.786 62.958 -25.211 1.00 11.25 ? 946 PHE A N 1 ATOM 7642 C CA . PHE A 1 946 ? 66.030 61.946 -24.175 1.00 11.31 ? 946 PHE A CA 1 ATOM 7643 C C . PHE A 1 946 ? 64.942 60.901 -24.281 1.00 10.52 ? 946 PHE A C 1 ATOM 7644 O O . PHE A 1 946 ? 63.778 61.253 -24.468 1.00 10.56 ? 946 PHE A O 1 ATOM 7645 C CB . PHE A 1 946 ? 66.057 62.559 -22.762 1.00 11.61 ? 946 PHE A CB 1 ATOM 7646 C CG . PHE A 1 946 ? 65.926 61.529 -21.663 1.00 11.60 ? 946 PHE A CG 1 ATOM 7647 C CD1 . PHE A 1 946 ? 66.980 60.666 -21.341 1.00 11.50 ? 946 PHE A CD1 1 ATOM 7648 C CD2 . PHE A 1 946 ? 64.711 61.388 -20.986 1.00 12.26 ? 946 PHE A CD2 1 ATOM 7649 C CE1 . PHE A 1 946 ? 66.817 59.684 -20.340 1.00 12.81 ? 946 PHE A CE1 1 ATOM 7650 C CE2 . PHE A 1 946 ? 64.542 60.420 -20.011 1.00 11.48 ? 946 PHE A CE2 1 ATOM 7651 C CZ . PHE A 1 946 ? 65.578 59.559 -19.695 1.00 12.97 ? 946 PHE A CZ 1 ATOM 7652 N N . GLY A 1 947 ? 65.298 59.613 -24.169 1.00 11.03 ? 947 GLY A N 1 ATOM 7653 C CA . GLY A 1 947 ? 64.317 58.554 -24.186 1.00 12.14 ? 947 GLY A CA 1 ATOM 7654 C C . GLY A 1 947 ? 63.966 57.987 -25.547 1.00 12.66 ? 947 GLY A C 1 ATOM 7655 O O . GLY A 1 947 ? 63.016 57.220 -25.659 1.00 12.82 ? 947 GLY A O 1 ATOM 7656 N N . GLY A 1 948 ? 64.752 58.312 -26.593 1.00 14.57 ? 948 GLY A N 1 ATOM 7657 C CA . GLY A 1 948 ? 64.498 57.767 -27.916 1.00 16.14 ? 948 GLY A CA 1 ATOM 7658 C C . GLY A 1 948 ? 64.546 56.242 -27.945 1.00 16.78 ? 948 GLY A C 1 ATOM 7659 O O . GLY A 1 948 ? 63.933 55.634 -28.828 1.00 19.03 ? 948 GLY A O 1 ATOM 7660 N N . ASP A 1 949 ? 65.247 55.634 -26.982 1.00 17.01 ? 949 ASP A N 1 ATOM 7661 C CA . ASP A 1 949 ? 65.316 54.169 -26.883 1.00 19.17 ? 949 ASP A CA 1 ATOM 7662 C C . ASP A 1 949 ? 64.316 53.542 -25.909 1.00 18.35 ? 949 ASP A C 1 ATOM 7663 O O . ASP A 1 949 ? 64.326 52.308 -25.674 1.00 19.30 ? 949 ASP A O 1 ATOM 7664 C CB . ASP A 1 949 ? 66.754 53.696 -26.559 1.00 20.38 ? 949 ASP A CB 1 ATOM 7665 C CG . ASP A 1 949 ? 67.287 54.229 -25.218 1.00 24.65 ? 949 ASP A CG 1 ATOM 7666 O OD1 . ASP A 1 949 ? 66.677 55.133 -24.578 1.00 26.75 ? 949 ASP A OD1 1 ATOM 7667 O OD2 . ASP A 1 949 ? 68.349 53.799 -24.707 1.00 30.82 ? 949 ASP A OD2 1 ATOM 7668 N N . HIS A 1 950 ? 63.430 54.366 -25.335 1.00 17.00 ? 950 HIS A N 1 ATOM 7669 C CA . HIS A 1 950 ? 62.414 53.830 -24.423 1.00 14.80 ? 950 HIS A CA 1 ATOM 7670 C C . HIS A 1 950 ? 61.346 53.073 -25.225 1.00 14.91 ? 950 HIS A C 1 ATOM 7671 O O . HIS A 1 950 ? 60.947 53.544 -26.280 1.00 15.39 ? 950 HIS A O 1 ATOM 7672 C CB . HIS A 1 950 ? 61.720 54.966 -23.660 1.00 13.72 ? 950 HIS A CB 1 ATOM 7673 C CG . HIS A 1 950 ? 62.597 55.677 -22.685 1.00 12.84 ? 950 HIS A CG 1 ATOM 7674 N ND1 . HIS A 1 950 ? 62.217 56.860 -22.092 1.00 11.11 ? 950 HIS A ND1 1 ATOM 7675 C CD2 . HIS A 1 950 ? 63.826 55.385 -22.189 1.00 13.28 ? 950 HIS A CD2 1 ATOM 7676 C CE1 . HIS A 1 950 ? 63.162 57.270 -21.269 1.00 12.06 ? 950 HIS A CE1 1 ATOM 7677 N NE2 . HIS A 1 950 ? 64.154 56.390 -21.304 1.00 13.63 ? 950 HIS A NE2 1 ATOM 7678 N N . PRO A 1 951 ? 60.889 51.907 -24.767 1.00 15.37 ? 951 PRO A N 1 ATOM 7679 C CA . PRO A 1 951 ? 59.833 51.175 -25.481 1.00 15.44 ? 951 PRO A CA 1 ATOM 7680 C C . PRO A 1 951 ? 58.538 51.972 -25.614 1.00 15.40 ? 951 PRO A C 1 ATOM 7681 O O . PRO A 1 951 ? 58.119 52.653 -24.650 1.00 15.26 ? 951 PRO A O 1 ATOM 7682 C CB . PRO A 1 951 ? 59.600 49.935 -24.594 1.00 16.21 ? 951 PRO A CB 1 ATOM 7683 C CG . PRO A 1 951 ? 60.890 49.766 -23.893 1.00 17.92 ? 951 PRO A CG 1 ATOM 7684 C CD . PRO A 1 951 ? 61.356 51.186 -23.565 1.00 16.96 ? 951 PRO A CD 1 ATOM 7685 N N . SER A 1 952 ? 57.897 51.890 -26.770 1.00 14.67 ? 952 SER A N 1 ATOM 7686 C CA . SER A 1 952 ? 56.634 52.566 -27.005 1.00 14.05 ? 952 SER A CA 1 ATOM 7687 C C . SER A 1 952 ? 55.520 51.544 -26.826 1.00 14.14 ? 952 SER A C 1 ATOM 7688 O O . SER A 1 952 ? 55.225 50.735 -27.732 1.00 15.20 ? 952 SER A O 1 ATOM 7689 C CB . SER A 1 952 ? 56.610 53.221 -28.387 1.00 14.36 ? 952 SER A CB 1 ATOM 7690 O OG . SER A 1 952 ? 55.540 54.135 -28.525 1.00 15.23 ? 952 SER A OG 1 ATOM 7691 N N . ALA A 1 953 ? 54.906 51.548 -25.644 1.00 13.37 ? 953 ALA A N 1 ATOM 7692 C CA . ALA A 1 953 ? 53.987 50.509 -25.216 1.00 13.20 ? 953 ALA A CA 1 ATOM 7693 C C . ALA A 1 953 ? 52.634 50.626 -25.875 1.00 12.65 ? 953 ALA A C 1 ATOM 7694 O O . ALA A 1 953 ? 52.229 51.704 -26.331 1.00 12.75 ? 953 ALA A O 1 ATOM 7695 C CB . ALA A 1 953 ? 53.820 50.545 -23.689 1.00 14.23 ? 953 ALA A CB 1 ATOM 7696 N N A ARG A 1 954 ? 51.902 49.518 -25.903 0.50 12.38 ? 954 ARG A N 1 ATOM 7697 N N B ARG A 1 954 ? 51.911 49.511 -25.882 0.50 12.07 ? 954 ARG A N 1 ATOM 7698 C CA A ARG A 1 954 ? 50.555 49.490 -26.451 0.50 13.23 ? 954 ARG A CA 1 ATOM 7699 C CA B ARG A 1 954 ? 50.531 49.446 -26.342 0.50 12.53 ? 954 ARG A CA 1 ATOM 7700 C C A ARG A 1 954 ? 49.695 50.570 -25.788 0.50 12.21 ? 954 ARG A C 1 ATOM 7701 C C B ARG A 1 954 ? 49.686 50.590 -25.760 0.50 11.85 ? 954 ARG A C 1 ATOM 7702 O O A ARG A 1 954 ? 49.851 50.868 -24.585 0.50 11.65 ? 954 ARG A O 1 ATOM 7703 O O B ARG A 1 954 ? 49.848 50.965 -24.580 0.50 11.02 ? 954 ARG A O 1 ATOM 7704 C CB A ARG A 1 954 ? 49.941 48.112 -26.243 0.50 13.71 ? 954 ARG A CB 1 ATOM 7705 C CB B ARG A 1 954 ? 49.925 48.090 -25.972 0.50 12.88 ? 954 ARG A CB 1 ATOM 7706 C CG A ARG A 1 954 ? 48.714 47.766 -27.101 0.50 15.29 ? 954 ARG A CG 1 ATOM 7707 C CG B ARG A 1 954 ? 50.102 47.713 -24.513 0.50 14.04 ? 954 ARG A CG 1 ATOM 7708 C CD A ARG A 1 954 ? 48.186 46.374 -26.778 0.50 16.42 ? 954 ARG A CD 1 ATOM 7709 C CD B ARG A 1 954 ? 49.613 46.315 -24.161 0.50 14.97 ? 954 ARG A CD 1 ATOM 7710 N NE A ARG A 1 954 ? 48.043 46.297 -25.326 0.50 21.86 ? 954 ARG A NE 1 ATOM 7711 N NE B ARG A 1 954 ? 48.250 46.089 -24.633 0.50 22.28 ? 954 ARG A NE 1 ATOM 7712 C CZ A ARG A 1 954 ? 48.949 45.830 -24.456 0.50 20.65 ? 954 ARG A CZ 1 ATOM 7713 C CZ B ARG A 1 954 ? 47.914 45.344 -25.686 0.50 22.25 ? 954 ARG A CZ 1 ATOM 7714 N NH1 A ARG A 1 954 ? 50.115 45.301 -24.841 0.50 20.85 ? 954 ARG A NH1 1 ATOM 7715 N NH1 B ARG A 1 954 ? 48.840 44.704 -26.395 0.50 23.61 ? 954 ARG A NH1 1 ATOM 7716 N NH2 A ARG A 1 954 ? 48.661 45.886 -23.167 0.50 19.71 ? 954 ARG A NH2 1 ATOM 7717 N NH2 B ARG A 1 954 ? 46.637 45.232 -26.020 0.50 24.37 ? 954 ARG A NH2 1 ATOM 7718 N N . GLU A 1 955 ? 48.767 51.112 -26.570 1.00 12.03 ? 955 GLU A N 1 ATOM 7719 C CA . GLU A 1 955 ? 48.040 52.329 -26.198 1.00 12.40 ? 955 GLU A CA 1 ATOM 7720 C C . GLU A 1 955 ? 47.214 52.204 -24.920 1.00 11.56 ? 955 GLU A C 1 ATOM 7721 O O . GLU A 1 955 ? 46.920 53.230 -24.277 1.00 12.17 ? 955 GLU A O 1 ATOM 7722 C CB . GLU A 1 955 ? 47.146 52.790 -27.352 1.00 14.45 ? 955 GLU A CB 1 ATOM 7723 C CG . GLU A 1 955 ? 46.097 51.769 -27.731 1.00 15.10 ? 955 GLU A CG 1 ATOM 7724 C CD . GLU A 1 955 ? 45.149 52.256 -28.798 1.00 21.17 ? 955 GLU A CD 1 ATOM 7725 O OE1 . GLU A 1 955 ? 44.959 53.492 -28.931 1.00 26.59 ? 955 GLU A OE1 1 ATOM 7726 O OE2 . GLU A 1 955 ? 44.601 51.382 -29.494 1.00 24.11 ? 955 GLU A OE2 1 ATOM 7727 N N . ASP A 1 956 ? 46.807 50.984 -24.583 1.00 10.30 ? 956 ASP A N 1 ATOM 7728 C CA . ASP A 1 956 ? 45.993 50.802 -23.384 1.00 10.83 ? 956 ASP A CA 1 ATOM 7729 C C . ASP A 1 956 ? 46.812 50.711 -22.095 1.00 9.92 ? 956 ASP A C 1 ATOM 7730 O O . ASP A 1 956 ? 46.212 50.620 -21.001 1.00 12.09 ? 956 ASP A O 1 ATOM 7731 C CB . ASP A 1 956 ? 44.987 49.640 -23.518 1.00 11.12 ? 956 ASP A CB 1 ATOM 7732 C CG . ASP A 1 956 ? 45.622 48.335 -23.854 1.00 14.55 ? 956 ASP A CG 1 ATOM 7733 O OD1 . ASP A 1 956 ? 46.839 48.282 -24.058 1.00 18.36 ? 956 ASP A OD1 1 ATOM 7734 O OD2 . ASP A 1 956 ? 44.920 47.292 -23.916 1.00 16.11 ? 956 ASP A OD2 1 ATOM 7735 N N . LEU A 1 957 ? 48.130 50.707 -22.198 1.00 9.33 ? 957 LEU A N 1 ATOM 7736 C CA . LEU A 1 957 ? 48.981 50.561 -21.004 1.00 10.37 ? 957 LEU A CA 1 ATOM 7737 C C . LEU A 1 957 ? 49.555 51.922 -20.606 1.00 9.54 ? 957 LEU A C 1 ATOM 7738 O O . LEU A 1 957 ? 50.011 52.689 -21.470 1.00 10.68 ? 957 LEU A O 1 ATOM 7739 C CB . LEU A 1 957 ? 50.125 49.584 -21.321 1.00 11.15 ? 957 LEU A CB 1 ATOM 7740 C CG . LEU A 1 957 ? 51.016 49.140 -20.161 1.00 13.67 ? 957 LEU A CG 1 ATOM 7741 C CD1 . LEU A 1 957 ? 50.216 48.389 -19.102 1.00 16.31 ? 957 LEU A CD1 1 ATOM 7742 C CD2 . LEU A 1 957 ? 52.123 48.236 -20.693 1.00 13.94 ? 957 LEU A CD2 1 ATOM 7743 N N . ASP A 1 958 ? 49.581 52.209 -19.306 1.00 8.82 ? 958 ASP A N 1 ATOM 7744 C CA . ASP A 1 958 ? 50.207 53.416 -18.796 1.00 8.29 ? 958 ASP A CA 1 ATOM 7745 C C . ASP A 1 958 ? 51.147 53.082 -17.657 1.00 7.21 ? 958 ASP A C 1 ATOM 7746 O O . ASP A 1 958 ? 50.903 52.127 -16.887 1.00 8.29 ? 958 ASP A O 1 ATOM 7747 C CB . ASP A 1 958 ? 49.139 54.393 -18.311 1.00 8.82 ? 958 ASP A CB 1 ATOM 7748 C CG . ASP A 1 958 ? 49.669 55.802 -18.134 1.00 9.29 ? 958 ASP A CG 1 ATOM 7749 O OD1 . ASP A 1 958 ? 50.784 56.129 -18.598 1.00 9.06 ? 958 ASP A OD1 1 ATOM 7750 O OD2 . ASP A 1 958 ? 48.956 56.610 -17.483 1.00 9.68 ? 958 ASP A OD2 1 ATOM 7751 N N . VAL A 1 959 ? 52.214 53.867 -17.551 1.00 7.93 ? 959 VAL A N 1 ATOM 7752 C CA . VAL A 1 959 ? 53.065 53.874 -16.363 1.00 7.96 ? 959 VAL A CA 1 ATOM 7753 C C . VAL A 1 959 ? 52.523 55.002 -15.510 1.00 7.83 ? 959 VAL A C 1 ATOM 7754 O O . VAL A 1 959 ? 52.922 56.172 -15.631 1.00 8.90 ? 959 VAL A O 1 ATOM 7755 C CB . VAL A 1 959 ? 54.527 54.109 -16.730 1.00 8.63 ? 959 VAL A CB 1 ATOM 7756 C CG1 . VAL A 1 959 ? 55.428 54.229 -15.453 1.00 8.77 ? 959 VAL A CG1 1 ATOM 7757 C CG2 . VAL A 1 959 ? 55.053 52.949 -17.615 1.00 10.08 ? 959 VAL A CG2 1 ATOM 7758 N N . SER A 1 960 ? 51.562 54.659 -14.656 1.00 7.75 ? 960 SER A N 1 ATOM 7759 C CA . SER A 1 960 ? 50.842 55.623 -13.844 1.00 8.20 ? 960 SER A CA 1 ATOM 7760 C C . SER A 1 960 ? 51.759 56.315 -12.855 1.00 8.29 ? 960 SER A C 1 ATOM 7761 O O . SER A 1 960 ? 51.588 57.529 -12.574 1.00 8.99 ? 960 SER A O 1 ATOM 7762 C CB . SER A 1 960 ? 49.733 54.944 -13.065 1.00 8.75 ? 960 SER A CB 1 ATOM 7763 O OG . SER A 1 960 ? 48.899 54.156 -13.913 1.00 11.13 ? 960 SER A OG 1 ATOM 7764 N N . VAL A 1 961 ? 52.729 55.567 -12.303 1.00 8.13 ? 961 VAL A N 1 ATOM 7765 C CA . VAL A 1 961 ? 53.721 56.073 -11.343 1.00 8.11 ? 961 VAL A CA 1 ATOM 7766 C C . VAL A 1 961 ? 55.090 55.525 -11.732 1.00 7.42 ? 961 VAL A C 1 ATOM 7767 O O . VAL A 1 961 ? 55.229 54.327 -11.994 1.00 7.36 ? 961 VAL A O 1 ATOM 7768 C CB . VAL A 1 961 ? 53.387 55.611 -9.930 1.00 8.57 ? 961 VAL A CB 1 ATOM 7769 C CG1 . VAL A 1 961 ? 54.496 56.000 -8.925 1.00 10.25 ? 961 VAL A CG1 1 ATOM 7770 C CG2 . VAL A 1 961 ? 52.052 56.168 -9.459 1.00 10.25 ? 961 VAL A CG2 1 ATOM 7771 N N . MET A 1 962 ? 56.079 56.416 -11.733 1.00 7.79 ? 962 MET A N 1 ATOM 7772 C CA . MET A 1 962 ? 57.483 56.014 -11.671 1.00 7.90 ? 962 MET A CA 1 ATOM 7773 C C . MET A 1 962 ? 58.074 56.845 -10.548 1.00 7.92 ? 962 MET A C 1 ATOM 7774 O O . MET A 1 962 ? 58.029 58.079 -10.559 1.00 8.58 ? 962 MET A O 1 ATOM 7775 C CB . MET A 1 962 ? 58.194 56.308 -13.007 1.00 7.86 ? 962 MET A CB 1 ATOM 7776 C CG . MET A 1 962 ? 59.693 56.003 -12.943 1.00 8.73 ? 962 MET A CG 1 ATOM 7777 S SD . MET A 1 962 ? 60.443 56.313 -14.541 1.00 10.33 ? 962 MET A SD 1 ATOM 7778 C CE . MET A 1 962 ? 62.192 55.834 -14.217 1.00 9.97 ? 962 MET A CE 1 ATOM 7779 N N . ARG A 1 963 ? 58.626 56.171 -9.548 1.00 8.06 ? 963 ARG A N 1 ATOM 7780 C CA . ARG A 1 963 ? 59.157 56.869 -8.386 1.00 8.01 ? 963 ARG A CA 1 ATOM 7781 C C . ARG A 1 963 ? 60.390 56.155 -7.859 1.00 8.25 ? 963 ARG A C 1 ATOM 7782 O O . ARG A 1 963 ? 60.343 54.959 -7.571 1.00 8.32 ? 963 ARG A O 1 ATOM 7783 C CB . ARG A 1 963 ? 58.096 56.966 -7.288 1.00 8.81 ? 963 ARG A CB 1 ATOM 7784 C CG . ARG A 1 963 ? 58.649 57.336 -5.921 1.00 8.88 ? 963 ARG A CG 1 ATOM 7785 C CD . ARG A 1 963 ? 57.558 57.327 -4.863 1.00 9.81 ? 963 ARG A CD 1 ATOM 7786 N NE . ARG A 1 963 ? 56.328 57.954 -5.339 1.00 9.52 ? 963 ARG A NE 1 ATOM 7787 C CZ . ARG A 1 963 ? 55.119 57.418 -5.212 1.00 9.21 ? 963 ARG A CZ 1 ATOM 7788 N NH1 . ARG A 1 963 ? 54.972 56.240 -4.622 1.00 9.18 ? 963 ARG A NH1 1 ATOM 7789 N NH2 . ARG A 1 963 ? 54.055 58.060 -5.676 1.00 9.96 ? 963 ARG A NH2 1 ATOM 7790 N N . ARG A 1 964 ? 61.494 56.883 -7.733 1.00 8.65 ? 964 ARG A N 1 ATOM 7791 C CA . ARG A 1 964 ? 62.673 56.307 -7.077 1.00 9.49 ? 964 ARG A CA 1 ATOM 7792 C C . ARG A 1 964 ? 62.387 56.255 -5.571 1.00 9.24 ? 964 ARG A C 1 ATOM 7793 O O . ARG A 1 964 ? 61.938 57.231 -4.965 1.00 9.48 ? 964 ARG A O 1 ATOM 7794 C CB . ARG A 1 964 ? 63.909 57.151 -7.388 1.00 8.75 ? 964 ARG A CB 1 ATOM 7795 C CG . ARG A 1 964 ? 65.196 56.481 -6.825 1.00 9.82 ? 964 ARG A CG 1 ATOM 7796 C CD . ARG A 1 964 ? 66.500 57.143 -7.277 1.00 10.39 ? 964 ARG A CD 1 ATOM 7797 N NE . ARG A 1 964 ? 66.677 56.998 -8.710 1.00 11.84 ? 964 ARG A NE 1 ATOM 7798 C CZ . ARG A 1 964 ? 67.602 56.246 -9.275 1.00 12.17 ? 964 ARG A CZ 1 ATOM 7799 N NH1 . ARG A 1 964 ? 68.463 55.536 -8.520 1.00 15.22 ? 964 ARG A NH1 1 ATOM 7800 N NH2 . ARG A 1 964 ? 67.708 56.196 -10.596 1.00 12.74 ? 964 ARG A NH2 1 ATOM 7801 N N . LEU A 1 965 ? 62.672 55.086 -5.001 1.00 9.19 ? 965 LEU A N 1 ATOM 7802 C CA . LEU A 1 965 ? 62.288 54.799 -3.623 1.00 9.04 ? 965 LEU A CA 1 ATOM 7803 C C . LEU A 1 965 ? 63.437 54.943 -2.623 1.00 10.88 ? 965 LEU A C 1 ATOM 7804 O O . LEU A 1 965 ? 63.211 54.863 -1.414 1.00 12.43 ? 965 LEU A O 1 ATOM 7805 C CB . LEU A 1 965 ? 61.740 53.389 -3.541 1.00 10.55 ? 965 LEU A CB 1 ATOM 7806 C CG . LEU A 1 965 ? 60.494 53.127 -4.409 1.00 9.51 ? 965 LEU A CG 1 ATOM 7807 C CD1 . LEU A 1 965 ? 60.090 51.679 -4.360 1.00 11.72 ? 965 LEU A CD1 1 ATOM 7808 C CD2 . LEU A 1 965 ? 59.304 54.003 -3.982 1.00 13.21 ? 965 LEU A CD2 1 ATOM 7809 N N . THR A 1 966 ? 64.659 55.122 -3.138 1.00 11.37 ? 966 THR A N 1 ATOM 7810 C CA . THR A 1 966 ? 65.883 55.189 -2.297 1.00 11.09 ? 966 THR A CA 1 ATOM 7811 C C . THR A 1 966 ? 66.574 56.516 -2.507 1.00 10.95 ? 966 THR A C 1 ATOM 7812 O O . THR A 1 966 ? 66.552 57.061 -3.606 1.00 11.54 ? 966 THR A O 1 ATOM 7813 C CB . THR A 1 966 ? 66.871 54.104 -2.713 1.00 12.34 ? 966 THR A CB 1 ATOM 7814 O OG1 . THR A 1 966 ? 66.901 54.006 -4.134 1.00 12.40 ? 966 THR A OG1 1 ATOM 7815 C CG2 . THR A 1 966 ? 66.440 52.722 -2.218 1.00 13.20 ? 966 THR A CG2 1 ATOM 7816 N N . LYS A 1 967 ? 67.226 57.002 -1.453 1.00 11.86 ? 967 LYS A N 1 ATOM 7817 C CA . LYS A 1 967 ? 68.067 58.190 -1.507 1.00 12.75 ? 967 LYS A CA 1 ATOM 7818 C C . LYS A 1 967 ? 69.454 57.762 -1.982 1.00 12.54 ? 967 LYS A C 1 ATOM 7819 O O . LYS A 1 967 ? 69.703 56.570 -2.131 1.00 12.49 ? 967 LYS A O 1 ATOM 7820 C CB . LYS A 1 967 ? 68.138 58.858 -0.138 1.00 13.39 ? 967 LYS A CB 1 ATOM 7821 C CG . LYS A 1 967 ? 66.739 59.312 0.386 1.00 17.63 ? 967 LYS A CG 1 ATOM 7822 C CD . LYS A 1 967 ? 66.883 60.114 1.668 1.00 22.78 ? 967 LYS A CD 1 ATOM 7823 C CE . LYS A 1 967 ? 65.536 60.404 2.319 1.00 29.20 ? 967 LYS A CE 1 ATOM 7824 N NZ . LYS A 1 967 ? 64.791 61.427 1.543 1.00 32.57 ? 967 LYS A NZ 1 ATOM 7825 N N . SER A 1 968 ? 70.305 58.754 -2.266 1.00 14.26 ? 968 SER A N 1 ATOM 7826 C CA . SER A 1 968 ? 71.572 58.492 -2.969 1.00 16.31 ? 968 SER A CA 1 ATOM 7827 C C . SER A 1 968 ? 72.551 57.626 -2.183 1.00 17.45 ? 968 SER A C 1 ATOM 7828 O O . SER A 1 968 ? 73.368 56.935 -2.793 1.00 19.51 ? 968 SER A O 1 ATOM 7829 C CB . SER A 1 968 ? 72.247 59.798 -3.377 1.00 16.83 ? 968 SER A CB 1 ATOM 7830 O OG . SER A 1 968 ? 72.498 60.607 -2.254 1.00 21.39 ? 968 SER A OG 1 ATOM 7831 N N . SER A 1 969 ? 72.418 57.615 -0.857 1.00 18.13 ? 969 SER A N 1 ATOM 7832 C CA . SER A 1 969 ? 73.348 56.838 -0.009 1.00 19.61 ? 969 SER A CA 1 ATOM 7833 C C . SER A 1 969 ? 73.096 55.329 -0.017 1.00 19.14 ? 969 SER A C 1 ATOM 7834 O O . SER A 1 969 ? 73.931 54.567 0.474 1.00 19.33 ? 969 SER A O 1 ATOM 7835 C CB . SER A 1 969 ? 73.371 57.380 1.407 1.00 21.45 ? 969 SER A CB 1 ATOM 7836 O OG . SER A 1 969 ? 72.070 57.326 1.950 1.00 25.72 ? 969 SER A OG 1 ATOM 7837 N N . ALA A 1 970 ? 71.966 54.871 -0.555 1.00 17.56 ? 970 ALA A N 1 ATOM 7838 C CA . ALA A 1 970 ? 71.689 53.445 -0.659 1.00 17.57 ? 970 ALA A CA 1 ATOM 7839 C C . ALA A 1 970 ? 72.539 52.759 -1.710 1.00 18.44 ? 970 ALA A C 1 ATOM 7840 O O . ALA A 1 970 ? 72.520 53.140 -2.885 1.00 17.48 ? 970 ALA A O 1 ATOM 7841 C CB . ALA A 1 970 ? 70.184 53.177 -0.950 1.00 17.86 ? 970 ALA A CB 1 ATOM 7842 N N A LYS A 1 971 ? 73.278 51.733 -1.280 0.50 18.77 ? 971 LYS A N 1 ATOM 7843 N N B LYS A 1 971 ? 73.288 51.737 -1.293 0.50 18.64 ? 971 LYS A N 1 ATOM 7844 C CA A LYS A 1 971 ? 74.073 50.885 -2.169 0.50 19.76 ? 971 LYS A CA 1 ATOM 7845 C CA B LYS A 1 971 ? 74.074 50.940 -2.230 0.50 19.54 ? 971 LYS A CA 1 ATOM 7846 C C A LYS A 1 971 ? 73.220 50.260 -3.275 0.50 19.47 ? 971 LYS A C 1 ATOM 7847 C C B LYS A 1 971 ? 73.182 50.333 -3.307 0.50 19.30 ? 971 LYS A C 1 ATOM 7848 O O A LYS A 1 971 ? 73.624 50.218 -4.435 0.50 19.89 ? 971 LYS A O 1 ATOM 7849 O O B LYS A 1 971 ? 73.518 50.389 -4.489 0.50 19.78 ? 971 LYS A O 1 ATOM 7850 C CB A LYS A 1 971 ? 74.765 49.782 -1.348 0.50 19.95 ? 971 LYS A CB 1 ATOM 7851 C CB B LYS A 1 971 ? 74.863 49.838 -1.504 0.50 19.66 ? 971 LYS A CB 1 ATOM 7852 C CG A LYS A 1 971 ? 75.802 48.956 -2.104 0.50 21.23 ? 971 LYS A CG 1 ATOM 7853 C CG B LYS A 1 971 ? 75.826 50.350 -0.447 0.50 20.94 ? 971 LYS A CG 1 ATOM 7854 C CD A LYS A 1 971 ? 76.513 47.947 -1.178 0.50 20.90 ? 971 LYS A CD 1 ATOM 7855 C CD B LYS A 1 971 ? 76.735 49.243 0.078 0.50 20.50 ? 971 LYS A CD 1 ATOM 7856 C CE A LYS A 1 971 ? 77.132 48.594 0.059 0.50 25.00 ? 971 LYS A CE 1 ATOM 7857 C CE B LYS A 1 971 ? 75.975 48.170 0.869 0.50 21.75 ? 971 LYS A CE 1 ATOM 7858 N NZ A LYS A 1 971 ? 78.198 49.595 -0.244 0.50 25.82 ? 971 LYS A NZ 1 ATOM 7859 N NZ B LYS A 1 971 ? 75.221 48.745 2.006 0.50 23.14 ? 971 LYS A NZ 1 ATOM 7860 N N . THR A 1 972 ? 72.046 49.759 -2.897 1.00 18.78 ? 972 THR A N 1 ATOM 7861 C CA . THR A 1 972 ? 71.090 49.211 -3.858 1.00 17.81 ? 972 THR A CA 1 ATOM 7862 C C . THR A 1 972 ? 69.967 50.232 -4.117 1.00 16.46 ? 972 THR A C 1 ATOM 7863 O O . THR A 1 972 ? 69.171 50.530 -3.225 1.00 16.63 ? 972 THR A O 1 ATOM 7864 C CB . THR A 1 972 ? 70.518 47.840 -3.420 1.00 18.53 ? 972 THR A CB 1 ATOM 7865 O OG1 . THR A 1 972 ? 71.600 46.911 -3.234 1.00 21.33 ? 972 THR A OG1 1 ATOM 7866 C CG2 . THR A 1 972 ? 69.727 47.185 -4.555 1.00 19.66 ? 972 THR A CG2 1 ATOM 7867 N N . GLN A 1 973 ? 69.947 50.789 -5.319 1.00 14.60 ? 973 GLN A N 1 ATOM 7868 C CA . GLN A 1 973 ? 68.888 51.753 -5.661 1.00 13.16 ? 973 GLN A CA 1 ATOM 7869 C C . GLN A 1 973 ? 67.629 50.984 -6.015 1.00 13.09 ? 973 GLN A C 1 ATOM 7870 O O . GLN A 1 973 ? 67.703 49.936 -6.621 1.00 13.81 ? 973 GLN A O 1 ATOM 7871 C CB . GLN A 1 973 ? 69.362 52.624 -6.826 1.00 12.17 ? 973 GLN A CB 1 ATOM 7872 C CG . GLN A 1 973 ? 70.453 53.630 -6.396 1.00 11.95 ? 973 GLN A CG 1 ATOM 7873 C CD . GLN A 1 973 ? 69.959 54.644 -5.392 1.00 13.57 ? 973 GLN A CD 1 ATOM 7874 O OE1 . GLN A 1 973 ? 68.940 55.314 -5.631 1.00 13.27 ? 973 GLN A OE1 1 ATOM 7875 N NE2 . GLN A 1 973 ? 70.647 54.784 -4.269 1.00 13.57 ? 973 GLN A NE2 1 ATOM 7876 N N . ARG A 1 974 ? 66.458 51.555 -5.681 1.00 12.32 ? 974 ARG A N 1 ATOM 7877 C CA A ARG A 1 974 ? 65.189 50.922 -6.031 0.50 11.67 ? 974 ARG A CA 1 ATOM 7878 C CA B ARG A 1 974 ? 65.158 50.931 -5.926 0.50 12.08 ? 974 ARG A CA 1 ATOM 7879 C C . ARG A 1 974 ? 64.245 51.921 -6.656 1.00 10.95 ? 974 ARG A C 1 ATOM 7880 O O . ARG A 1 974 ? 64.159 53.056 -6.218 1.00 10.76 ? 974 ARG A O 1 ATOM 7881 C CB A ARG A 1 974 ? 64.507 50.285 -4.833 0.50 11.88 ? 974 ARG A CB 1 ATOM 7882 C CB B ARG A 1 974 ? 64.516 50.536 -4.593 0.50 12.00 ? 974 ARG A CB 1 ATOM 7883 C CG A ARG A 1 974 ? 65.342 49.201 -4.141 0.50 10.93 ? 974 ARG A CG 1 ATOM 7884 C CG B ARG A 1 974 ? 65.254 49.381 -3.863 0.50 12.16 ? 974 ARG A CG 1 ATOM 7885 C CD A ARG A 1 974 ? 64.852 48.859 -2.741 0.50 13.78 ? 974 ARG A CD 1 ATOM 7886 C CD B ARG A 1 974 ? 64.900 49.225 -2.374 0.50 14.03 ? 974 ARG A CD 1 ATOM 7887 N NE A ARG A 1 974 ? 63.588 48.144 -2.766 0.50 15.48 ? 974 ARG A NE 1 ATOM 7888 N NE B ARG A 1 974 ? 63.466 49.274 -2.112 0.50 17.02 ? 974 ARG A NE 1 ATOM 7889 C CZ A ARG A 1 974 ? 62.432 48.559 -2.242 0.50 16.25 ? 974 ARG A CZ 1 ATOM 7890 C CZ B ARG A 1 974 ? 62.609 48.273 -2.294 0.50 20.13 ? 974 ARG A CZ 1 ATOM 7891 N NH1 A ARG A 1 974 ? 62.308 49.716 -1.598 0.50 15.55 ? 974 ARG A NH1 1 ATOM 7892 N NH1 B ARG A 1 974 ? 63.015 47.096 -2.759 0.50 20.80 ? 974 ARG A NH1 1 ATOM 7893 N NH2 A ARG A 1 974 ? 61.382 47.773 -2.367 0.50 13.98 ? 974 ARG A NH2 1 ATOM 7894 N NH2 B ARG A 1 974 ? 61.325 48.459 -2.022 0.50 19.37 ? 974 ARG A NH2 1 ATOM 7895 N N . VAL A 1 975 ? 63.582 51.481 -7.712 1.00 10.50 ? 975 VAL A N 1 ATOM 7896 C CA . VAL A 1 975 ? 62.630 52.350 -8.426 1.00 10.92 ? 975 VAL A CA 1 ATOM 7897 C C . VAL A 1 975 ? 61.328 51.592 -8.519 1.00 10.46 ? 975 VAL A C 1 ATOM 7898 O O . VAL A 1 975 ? 61.303 50.426 -8.953 1.00 10.75 ? 975 VAL A O 1 ATOM 7899 C CB . VAL A 1 975 ? 63.159 52.716 -9.839 1.00 11.16 ? 975 VAL A CB 1 ATOM 7900 C CG1 . VAL A 1 975 ? 62.149 53.610 -10.576 1.00 11.85 ? 975 VAL A CG1 1 ATOM 7901 C CG2 . VAL A 1 975 ? 64.487 53.515 -9.734 1.00 14.10 ? 975 VAL A CG2 1 ATOM 7902 N N . GLY A 1 976 ? 60.240 52.273 -8.148 1.00 9.31 ? 976 GLY A N 1 ATOM 7903 C CA . GLY A 1 976 ? 58.920 51.669 -8.197 1.00 10.09 ? 976 GLY A CA 1 ATOM 7904 C C . GLY A 1 976 ? 58.105 52.165 -9.377 1.00 8.60 ? 976 GLY A C 1 ATOM 7905 O O . GLY A 1 976 ? 58.189 53.347 -9.759 1.00 9.24 ? 976 GLY A O 1 ATOM 7906 N N . TYR A 1 977 ? 57.337 51.261 -9.945 1.00 8.42 ? 977 TYR A N 1 ATOM 7907 C CA . TYR A 1 977 ? 56.457 51.553 -11.077 1.00 7.90 ? 977 TYR A CA 1 ATOM 7908 C C . TYR A 1 977 ? 55.062 51.041 -10.771 1.00 8.08 ? 977 TYR A C 1 ATOM 7909 O O . TYR A 1 977 ? 54.912 49.914 -10.278 1.00 8.84 ? 977 TYR A O 1 ATOM 7910 C CB . TYR A 1 977 ? 56.937 50.823 -12.332 1.00 8.83 ? 977 TYR A CB 1 ATOM 7911 C CG . TYR A 1 977 ? 58.334 51.191 -12.742 1.00 8.68 ? 977 TYR A CG 1 ATOM 7912 C CD1 . TYR A 1 977 ? 58.555 52.264 -13.615 1.00 9.75 ? 977 TYR A CD1 1 ATOM 7913 C CD2 . TYR A 1 977 ? 59.439 50.489 -12.246 1.00 10.57 ? 977 TYR A CD2 1 ATOM 7914 C CE1 . TYR A 1 977 ? 59.827 52.619 -14.025 1.00 10.17 ? 977 TYR A CE1 1 ATOM 7915 C CE2 . TYR A 1 977 ? 60.753 50.843 -12.670 1.00 10.88 ? 977 TYR A CE2 1 ATOM 7916 C CZ . TYR A 1 977 ? 60.916 51.919 -13.541 1.00 10.07 ? 977 TYR A CZ 1 ATOM 7917 O OH . TYR A 1 977 ? 62.170 52.322 -13.987 1.00 11.67 ? 977 TYR A OH 1 ATOM 7918 N N . VAL A 1 978 ? 54.031 51.847 -11.071 1.00 7.61 ? 978 VAL A N 1 ATOM 7919 C CA . VAL A 1 978 ? 52.657 51.354 -11.076 1.00 8.22 ? 978 VAL A CA 1 ATOM 7920 C C . VAL A 1 978 ? 52.218 51.317 -12.534 1.00 8.33 ? 978 VAL A C 1 ATOM 7921 O O . VAL A 1 978 ? 52.308 52.347 -13.225 1.00 8.72 ? 978 VAL A O 1 ATOM 7922 C CB . VAL A 1 978 ? 51.682 52.240 -10.266 1.00 8.41 ? 978 VAL A CB 1 ATOM 7923 C CG1 . VAL A 1 978 ? 50.260 51.711 -10.437 1.00 9.35 ? 978 VAL A CG1 1 ATOM 7924 C CG2 . VAL A 1 978 ? 52.108 52.234 -8.775 1.00 9.24 ? 978 VAL A CG2 1 ATOM 7925 N N . LEU A 1 979 ? 51.833 50.146 -13.013 1.00 8.25 ? 979 LEU A N 1 ATOM 7926 C CA . LEU A 1 979 ? 51.367 49.957 -14.371 1.00 9.96 ? 979 LEU A CA 1 ATOM 7927 C C . LEU A 1 979 ? 49.884 49.705 -14.355 1.00 9.31 ? 979 LEU A C 1 ATOM 7928 O O . LEU A 1 979 ? 49.391 48.838 -13.640 1.00 11.22 ? 979 LEU A O 1 ATOM 7929 C CB . LEU A 1 979 ? 51.999 48.713 -15.006 1.00 12.83 ? 979 LEU A CB 1 ATOM 7930 C CG . LEU A 1 979 ? 53.509 48.672 -15.165 1.00 17.41 ? 979 LEU A CG 1 ATOM 7931 C CD1 . LEU A 1 979 ? 53.849 47.627 -16.236 1.00 21.54 ? 979 LEU A CD1 1 ATOM 7932 C CD2 . LEU A 1 979 ? 54.051 50.023 -15.551 1.00 21.99 ? 979 LEU A CD2 1 ATOM 7933 N N . HIS A 1 980 ? 49.160 50.449 -15.169 1.00 8.55 ? 980 HIS A N 1 ATOM 7934 C CA . HIS A 1 980 ? 47.731 50.271 -15.320 1.00 9.29 ? 980 HIS A CA 1 ATOM 7935 C C . HIS A 1 980 ? 47.345 49.986 -16.762 1.00 9.76 ? 980 HIS A C 1 ATOM 7936 O O . HIS A 1 980 ? 47.779 50.727 -17.652 1.00 10.46 ? 980 HIS A O 1 ATOM 7937 C CB . HIS A 1 980 ? 46.956 51.528 -14.861 1.00 9.58 ? 980 HIS A CB 1 ATOM 7938 C CG . HIS A 1 980 ? 45.486 51.381 -15.032 1.00 9.81 ? 980 HIS A CG 1 ATOM 7939 N ND1 . HIS A 1 980 ? 44.764 50.448 -14.325 1.00 9.84 ? 980 HIS A ND1 1 ATOM 7940 C CD2 . HIS A 1 980 ? 44.617 51.944 -15.905 1.00 10.10 ? 980 HIS A CD2 1 ATOM 7941 C CE1 . HIS A 1 980 ? 43.503 50.464 -14.730 1.00 11.98 ? 980 HIS A CE1 1 ATOM 7942 N NE2 . HIS A 1 980 ? 43.389 51.362 -15.693 1.00 11.40 ? 980 HIS A NE2 1 ATOM 7943 N N . ARG A 1 981 ? 46.586 48.917 -17.003 1.00 8.54 ? 981 ARG A N 1 ATOM 7944 C CA . ARG A 1 981 ? 46.089 48.674 -18.351 1.00 9.66 ? 981 ARG A CA 1 ATOM 7945 C C . ARG A 1 981 ? 44.600 48.875 -18.314 1.00 9.32 ? 981 ARG A C 1 ATOM 7946 O O . ARG A 1 981 ? 43.905 48.244 -17.511 1.00 9.70 ? 981 ARG A O 1 ATOM 7947 C CB . ARG A 1 981 ? 46.417 47.263 -18.793 1.00 11.57 ? 981 ARG A CB 1 ATOM 7948 C CG . ARG A 1 981 ? 46.129 47.065 -20.246 1.00 15.74 ? 981 ARG A CG 1 ATOM 7949 C CD . ARG A 1 981 ? 46.805 45.854 -20.783 1.00 20.89 ? 981 ARG A CD 1 ATOM 7950 N NE . ARG A 1 981 ? 46.214 45.483 -22.046 1.00 23.52 ? 981 ARG A NE 1 ATOM 7951 C CZ . ARG A 1 981 ? 46.243 44.251 -22.527 1.00 27.12 ? 981 ARG A CZ 1 ATOM 7952 N NH1 . ARG A 1 981 ? 46.844 43.285 -21.830 1.00 26.40 ? 981 ARG A NH1 1 ATOM 7953 N NH2 . ARG A 1 981 ? 45.671 43.986 -23.696 1.00 27.77 ? 981 ARG A NH2 1 ATOM 7954 N N . THR A 1 982 ? 44.105 49.779 -19.149 1.00 9.89 ? 982 THR A N 1 ATOM 7955 C CA . THR A 1 982 ? 42.664 49.963 -19.256 1.00 9.91 ? 982 THR A CA 1 ATOM 7956 C C . THR A 1 982 ? 42.113 48.911 -20.228 1.00 10.30 ? 982 THR A C 1 ATOM 7957 O O . THR A 1 982 ? 42.834 47.995 -20.602 1.00 11.88 ? 982 THR A O 1 ATOM 7958 C CB . THR A 1 982 ? 42.362 51.417 -19.682 1.00 9.77 ? 982 THR A CB 1 ATOM 7959 O OG1 . THR A 1 982 ? 40.959 51.681 -19.549 1.00 10.51 ? 982 THR A OG1 1 ATOM 7960 C CG2 . THR A 1 982 ? 42.780 51.735 -21.138 1.00 11.57 ? 982 THR A CG2 1 ATOM 7961 N N . ASN A 1 983 ? 40.834 49.005 -20.550 1.00 10.31 ? 983 ASN A N 1 ATOM 7962 C CA . ASN A 1 983 ? 40.252 48.130 -21.583 1.00 10.21 ? 983 ASN A CA 1 ATOM 7963 C C . ASN A 1 983 ? 39.522 49.010 -22.586 1.00 10.53 ? 983 ASN A C 1 ATOM 7964 O O . ASN A 1 983 ? 38.657 49.790 -22.204 1.00 10.95 ? 983 ASN A O 1 ATOM 7965 C CB . ASN A 1 983 ? 39.290 47.106 -20.989 1.00 10.64 ? 983 ASN A CB 1 ATOM 7966 C CG . ASN A 1 983 ? 38.776 46.150 -22.031 1.00 10.40 ? 983 ASN A CG 1 ATOM 7967 O OD1 . ASN A 1 983 ? 39.503 45.276 -22.431 1.00 12.66 ? 983 ASN A OD1 1 ATOM 7968 N ND2 . ASN A 1 983 ? 37.565 46.361 -22.500 1.00 10.90 ? 983 ASN A ND2 1 ATOM 7969 N N . LEU A 1 984 ? 39.976 48.939 -23.832 1.00 9.97 ? 984 LEU A N 1 ATOM 7970 C CA . LEU A 1 984 ? 39.423 49.734 -24.941 1.00 11.75 ? 984 LEU A CA 1 ATOM 7971 C C . LEU A 1 984 ? 38.599 48.828 -25.829 1.00 13.24 ? 984 LEU A C 1 ATOM 7972 O O . LEU A 1 984 ? 38.929 47.658 -26.010 1.00 12.96 ? 984 LEU A O 1 ATOM 7973 C CB . LEU A 1 984 ? 40.555 50.339 -25.773 1.00 12.09 ? 984 LEU A CB 1 ATOM 7974 C CG . LEU A 1 984 ? 41.515 51.195 -24.933 1.00 13.23 ? 984 LEU A CG 1 ATOM 7975 C CD1 . LEU A 1 984 ? 42.676 51.654 -25.798 1.00 15.27 ? 984 LEU A CD1 1 ATOM 7976 C CD2 . LEU A 1 984 ? 40.803 52.361 -24.265 1.00 12.13 ? 984 LEU A CD2 1 ATOM 7977 N N A MET A 1 985 ? 37.535 49.369 -26.393 0.50 13.61 ? 985 MET A N 1 ATOM 7978 N N B MET A 1 985 ? 37.525 49.371 -26.390 0.50 13.68 ? 985 MET A N 1 ATOM 7979 C CA A MET A 1 985 ? 36.655 48.595 -27.266 0.50 15.93 ? 985 MET A CA 1 ATOM 7980 C CA B MET A 1 985 ? 36.633 48.620 -27.289 0.50 15.91 ? 985 MET A CA 1 ATOM 7981 C C A MET A 1 985 ? 37.343 48.168 -28.541 0.50 16.46 ? 985 MET A C 1 ATOM 7982 C C B MET A 1 985 ? 37.354 48.164 -28.538 0.50 16.55 ? 985 MET A C 1 ATOM 7983 O O A MET A 1 985 ? 38.113 48.919 -29.111 0.50 16.58 ? 985 MET A O 1 ATOM 7984 O O B MET A 1 985 ? 38.135 48.906 -29.105 0.50 16.57 ? 985 MET A O 1 ATOM 7985 C CB A MET A 1 985 ? 35.426 49.413 -27.606 0.50 15.59 ? 985 MET A CB 1 ATOM 7986 C CB B MET A 1 985 ? 35.472 49.494 -27.754 0.50 16.31 ? 985 MET A CB 1 ATOM 7987 C CG A MET A 1 985 ? 34.523 49.620 -26.439 0.50 17.24 ? 985 MET A CG 1 ATOM 7988 C CG B MET A 1 985 ? 34.552 50.005 -26.696 0.50 17.40 ? 985 MET A CG 1 ATOM 7989 S SD A MET A 1 985 ? 32.830 49.414 -26.954 0.50 18.00 ? 985 MET A SD 1 ATOM 7990 S SD B MET A 1 985 ? 32.888 49.377 -26.922 0.50 22.34 ? 985 MET A SD 1 ATOM 7991 C CE A MET A 1 985 ? 32.675 50.955 -27.843 0.50 18.35 ? 985 MET A CE 1 ATOM 7992 C CE B MET A 1 985 ? 33.126 48.096 -25.708 0.50 16.90 ? 985 MET A CE 1 ATOM 7993 N N . GLN A 1 986 ? 37.048 46.947 -28.973 1.00 17.35 ? 986 GLN A N 1 ATOM 7994 C CA . GLN A 1 986 ? 37.518 46.444 -30.263 1.00 18.77 ? 986 GLN A CA 1 ATOM 7995 C C . GLN A 1 986 ? 36.517 46.941 -31.282 1.00 18.70 ? 986 GLN A C 1 ATOM 7996 O O . GLN A 1 986 ? 35.343 46.593 -31.215 1.00 18.26 ? 986 GLN A O 1 ATOM 7997 C CB . GLN A 1 986 ? 37.520 44.901 -30.288 1.00 20.24 ? 986 GLN A CB 1 ATOM 7998 C CG . GLN A 1 986 ? 38.510 44.220 -29.358 1.00 23.64 ? 986 GLN A CG 1 ATOM 7999 C CD . GLN A 1 986 ? 39.944 44.364 -29.827 1.00 28.82 ? 986 GLN A CD 1 ATOM 8000 O OE1 . GLN A 1 986 ? 40.214 44.432 -31.036 1.00 30.67 ? 986 GLN A OE1 1 ATOM 8001 N NE2 . GLN A 1 986 ? 40.867 44.420 -28.877 1.00 31.42 ? 986 GLN A NE2 1 ATOM 8002 N N . CYS A 1 987 ? 36.975 47.780 -32.209 1.00 20.01 ? 987 CYS A N 1 ATOM 8003 C CA . CYS A 1 987 ? 36.080 48.295 -33.242 1.00 21.96 ? 987 CYS A CA 1 ATOM 8004 C C . CYS A 1 987 ? 36.575 48.042 -34.666 1.00 23.25 ? 987 CYS A C 1 ATOM 8005 O O . CYS A 1 987 ? 36.062 48.653 -35.603 1.00 23.42 ? 987 CYS A O 1 ATOM 8006 C CB . CYS A 1 987 ? 35.753 49.772 -33.017 1.00 22.10 ? 987 CYS A CB 1 ATOM 8007 S SG . CYS A 1 987 ? 35.103 50.119 -31.366 1.00 24.16 ? 987 CYS A SG 1 ATOM 8008 N N . GLY A 1 988 ? 37.538 47.141 -34.830 1.00 24.71 ? 988 GLY A N 1 ATOM 8009 C CA . GLY A 1 988 ? 37.997 46.761 -36.157 1.00 29.32 ? 988 GLY A CA 1 ATOM 8010 C C . GLY A 1 988 ? 39.221 47.482 -36.672 1.00 32.36 ? 988 GLY A C 1 ATOM 8011 O O . GLY A 1 988 ? 39.609 47.295 -37.836 1.00 32.74 ? 988 GLY A O 1 ATOM 8012 N N . THR A 1 989 ? 39.841 48.299 -35.823 1.00 34.80 ? 989 THR A N 1 ATOM 8013 C CA . THR A 1 989 ? 41.086 48.969 -36.189 1.00 37.44 ? 989 THR A CA 1 ATOM 8014 C C . THR A 1 989 ? 42.253 48.076 -35.790 1.00 39.27 ? 989 THR A C 1 ATOM 8015 O O . THR A 1 989 ? 42.442 47.805 -34.603 1.00 39.39 ? 989 THR A O 1 ATOM 8016 C CB . THR A 1 989 ? 41.196 50.331 -35.493 1.00 37.19 ? 989 THR A CB 1 ATOM 8017 O OG1 . THR A 1 989 ? 39.985 51.070 -35.700 1.00 37.66 ? 989 THR A OG1 1 ATOM 8018 C CG2 . THR A 1 989 ? 42.266 51.188 -36.160 1.00 37.58 ? 989 THR A CG2 1 ATOM 8019 N N . PRO A 1 990 ? 43.028 47.606 -36.770 1.00 41.21 ? 990 PRO A N 1 ATOM 8020 C CA . PRO A 1 990 ? 44.168 46.729 -36.477 1.00 42.54 ? 990 PRO A CA 1 ATOM 8021 C C . PRO A 1 990 ? 45.164 47.358 -35.493 1.00 43.83 ? 990 PRO A C 1 ATOM 8022 O O . PRO A 1 990 ? 45.609 46.632 -34.600 1.00 44.32 ? 990 PRO A O 1 ATOM 8023 C CB . PRO A 1 990 ? 44.812 46.510 -37.852 1.00 42.71 ? 990 PRO A CB 1 ATOM 8024 C CG . PRO A 1 990 ? 43.702 46.745 -38.832 1.00 42.20 ? 990 PRO A CG 1 ATOM 8025 C CD . PRO A 1 990 ? 42.899 47.874 -38.216 1.00 41.41 ? 990 PRO A CD 1 ATOM 8026 N N . GLU A 1 991 ? 45.478 48.652 -35.633 1.00 44.65 ? 991 GLU A N 1 ATOM 8027 C CA . GLU A 1 991 ? 46.472 49.328 -34.782 1.00 45.83 ? 991 GLU A CA 1 ATOM 8028 C C . GLU A 1 991 ? 47.468 48.345 -34.147 1.00 45.85 ? 991 GLU A C 1 ATOM 8029 O O . GLU A 1 991 ? 47.294 47.931 -33.004 1.00 46.58 ? 991 GLU A O 1 ATOM 8030 C CB . GLU A 1 991 ? 45.770 50.152 -33.693 1.00 45.64 ? 991 GLU A CB 1 ATOM 8031 C CG . GLU A 1 991 ? 45.485 51.600 -34.069 1.00 46.46 ? 991 GLU A CG 1 ATOM 8032 C CD . GLU A 1 991 ? 44.434 52.258 -33.179 1.00 46.86 ? 991 GLU A CD 1 ATOM 8033 O OE1 . GLU A 1 991 ? 43.983 51.628 -32.194 1.00 47.34 ? 991 GLU A OE1 1 ATOM 8034 O OE2 . GLU A 1 991 ? 44.045 53.413 -33.470 1.00 48.43 ? 991 GLU A OE2 1 ATOM 8035 N N . GLU A 1 992 ? 48.499 47.952 -34.885 1.00 45.88 ? 992 GLU A N 1 ATOM 8036 C CA . GLU A 1 992 ? 49.355 46.865 -34.412 1.00 45.83 ? 992 GLU A CA 1 ATOM 8037 C C . GLU A 1 992 ? 50.805 47.252 -34.145 1.00 44.85 ? 992 GLU A C 1 ATOM 8038 O O . GLU A 1 992 ? 51.127 48.439 -34.020 1.00 45.44 ? 992 GLU A O 1 ATOM 8039 C CB . GLU A 1 992 ? 49.271 45.646 -35.350 1.00 46.35 ? 992 GLU A CB 1 ATOM 8040 C CG . GLU A 1 992 ? 48.043 44.761 -35.137 1.00 48.19 ? 992 GLU A CG 1 ATOM 8041 C CD . GLU A 1 992 ? 47.793 44.402 -33.670 1.00 51.20 ? 992 GLU A CD 1 ATOM 8042 O OE1 . GLU A 1 992 ? 48.768 44.111 -32.930 1.00 52.08 ? 992 GLU A OE1 1 ATOM 8043 O OE2 . GLU A 1 992 ? 46.609 44.401 -33.254 1.00 52.26 ? 992 GLU A OE2 1 ATOM 8044 N N . HIS A 1 993 ? 51.656 46.237 -34.088 1.00 43.41 ? 993 HIS A N 1 ATOM 8045 C CA . HIS A 1 993 ? 53.065 46.372 -33.732 1.00 41.97 ? 993 HIS A CA 1 ATOM 8046 C C . HIS A 1 993 ? 53.373 47.409 -32.671 1.00 40.01 ? 993 HIS A C 1 ATOM 8047 O O . HIS A 1 993 ? 53.534 48.590 -32.968 1.00 40.33 ? 993 HIS A O 1 ATOM 8048 C CB . HIS A 1 993 ? 53.952 46.554 -34.972 1.00 42.82 ? 993 HIS A CB 1 ATOM 8049 C CG . HIS A 1 993 ? 53.895 47.924 -35.577 1.00 44.10 ? 993 HIS A CG 1 ATOM 8050 N ND1 . HIS A 1 993 ? 54.503 49.018 -35.006 1.00 46.43 ? 993 HIS A ND1 1 ATOM 8051 C CD2 . HIS A 1 993 ? 53.305 48.372 -36.707 1.00 45.73 ? 993 HIS A CD2 1 ATOM 8052 C CE1 . HIS A 1 993 ? 54.296 50.079 -35.759 1.00 46.85 ? 993 HIS A CE1 1 ATOM 8053 N NE2 . HIS A 1 993 ? 53.565 49.715 -36.795 1.00 46.69 ? 993 HIS A NE2 1 ATOM 8054 N N . THR A 1 994 ? 53.434 46.971 -31.420 1.00 36.81 ? 994 THR A N 1 ATOM 8055 C CA . THR A 1 994 ? 54.062 47.787 -30.379 1.00 33.72 ? 994 THR A CA 1 ATOM 8056 C C . THR A 1 994 ? 55.110 46.990 -29.613 1.00 31.98 ? 994 THR A C 1 ATOM 8057 O O . THR A 1 994 ? 55.121 45.754 -29.641 1.00 32.13 ? 994 THR A O 1 ATOM 8058 C CB . THR A 1 994 ? 53.026 48.432 -29.419 1.00 33.70 ? 994 THR A CB 1 ATOM 8059 O OG1 . THR A 1 994 ? 52.092 47.443 -28.969 1.00 32.70 ? 994 THR A OG1 1 ATOM 8060 C CG2 . THR A 1 994 ? 52.154 49.446 -30.156 1.00 32.62 ? 994 THR A CG2 1 ATOM 8061 N N . GLN A 1 995 ? 55.984 47.703 -28.912 1.00 29.26 ? 995 GLN A N 1 ATOM 8062 C CA . GLN A 1 995 ? 57.035 47.053 -28.148 1.00 26.55 ? 995 GLN A CA 1 ATOM 8063 C C . GLN A 1 995 ? 56.555 46.695 -26.744 1.00 24.60 ? 995 GLN A C 1 ATOM 8064 O O . GLN A 1 995 ? 55.820 47.456 -26.101 1.00 23.16 ? 995 GLN A O 1 ATOM 8065 C CB . GLN A 1 995 ? 58.276 47.946 -28.069 1.00 26.55 ? 995 GLN A CB 1 ATOM 8066 C CG . GLN A 1 995 ? 58.867 48.305 -29.433 1.00 27.94 ? 995 GLN A CG 1 ATOM 8067 C CD . GLN A 1 995 ? 59.607 49.641 -29.446 1.00 30.17 ? 995 GLN A CD 1 ATOM 8068 O OE1 . GLN A 1 995 ? 59.009 50.700 -29.665 1.00 23.81 ? 995 GLN A OE1 1 ATOM 8069 N NE2 . GLN A 1 995 ? 60.922 49.588 -29.241 1.00 32.15 ? 995 GLN A NE2 1 ATOM 8070 N N . LYS A 1 996 ? 56.991 45.533 -26.264 1.00 22.28 ? 996 LYS A N 1 ATOM 8071 C CA . LYS A 1 996 ? 56.756 45.149 -24.883 1.00 21.94 ? 996 LYS A CA 1 ATOM 8072 C C . LYS A 1 996 ? 57.470 46.138 -23.981 1.00 20.28 ? 996 LYS A C 1 ATOM 8073 O O . LYS A 1 996 ? 58.640 46.477 -24.201 1.00 20.06 ? 996 LYS A O 1 ATOM 8074 C CB . LYS A 1 996 ? 57.277 43.726 -24.621 1.00 22.90 ? 996 LYS A CB 1 ATOM 8075 C CG . LYS A 1 996 ? 56.368 42.651 -25.189 1.00 26.22 ? 996 LYS A CG 1 ATOM 8076 C CD . LYS A 1 996 ? 54.949 42.763 -24.625 1.00 30.97 ? 996 LYS A CD 1 ATOM 8077 C CE . LYS A 1 996 ? 54.297 41.398 -24.494 1.00 32.52 ? 996 LYS A CE 1 ATOM 8078 N NZ . LYS A 1 996 ? 54.202 40.699 -25.811 1.00 34.81 ? 996 LYS A NZ 1 ATOM 8079 N N . LEU A 1 997 ? 56.760 46.590 -22.955 1.00 19.13 ? 997 LEU A N 1 ATOM 8080 C CA . LEU A 1 997 ? 57.384 47.429 -21.968 1.00 18.35 ? 997 LEU A CA 1 ATOM 8081 C C . LEU A 1 997 ? 57.736 46.571 -20.764 1.00 17.71 ? 997 LEU A C 1 ATOM 8082 O O . LEU A 1 997 ? 56.848 46.005 -20.126 1.00 18.52 ? 997 LEU A O 1 ATOM 8083 C CB . LEU A 1 997 ? 56.413 48.547 -21.568 1.00 18.89 ? 997 LEU A CB 1 ATOM 8084 C CG . LEU A 1 997 ? 56.875 49.404 -20.392 1.00 17.61 ? 997 LEU A CG 1 ATOM 8085 C CD1 . LEU A 1 997 ? 58.139 50.186 -20.737 1.00 21.29 ? 997 LEU A CD1 1 ATOM 8086 C CD2 . LEU A 1 997 ? 55.757 50.342 -20.038 1.00 20.48 ? 997 LEU A CD2 1 ATOM 8087 N N . ASP A 1 998 ? 59.031 46.508 -20.454 1.00 16.85 ? 998 ASP A N 1 ATOM 8088 C CA . ASP A 1 998 ? 59.515 45.878 -19.227 1.00 17.20 ? 998 ASP A CA 1 ATOM 8089 C C . ASP A 1 998 ? 60.104 46.974 -18.353 1.00 15.99 ? 998 ASP A C 1 ATOM 8090 O O . ASP A 1 998 ? 61.238 47.422 -18.544 1.00 16.00 ? 998 ASP A O 1 ATOM 8091 C CB . ASP A 1 998 ? 60.552 44.783 -19.553 1.00 17.84 ? 998 ASP A CB 1 ATOM 8092 C CG . ASP A 1 998 ? 61.265 44.264 -18.330 1.00 20.48 ? 998 ASP A CG 1 ATOM 8093 O OD1 . ASP A 1 998 ? 60.783 44.467 -17.177 1.00 18.65 ? 998 ASP A OD1 1 ATOM 8094 O OD2 . ASP A 1 998 ? 62.347 43.632 -18.447 1.00 22.64 ? 998 ASP A OD2 1 ATOM 8095 N N . VAL A 1 999 ? 59.325 47.414 -17.372 1.00 15.40 ? 999 VAL A N 1 ATOM 8096 C CA . VAL A 1 999 ? 59.781 48.545 -16.572 1.00 13.96 ? 999 VAL A CA 1 ATOM 8097 C C . VAL A 1 999 ? 61.046 48.245 -15.786 1.00 14.40 ? 999 VAL A C 1 ATOM 8098 O O . VAL A 1 999 ? 61.813 49.155 -15.443 1.00 14.14 ? 999 VAL A O 1 ATOM 8099 C CB . VAL A 1 999 ? 58.674 49.091 -15.636 1.00 13.93 ? 999 VAL A CB 1 ATOM 8100 C CG1 . VAL A 1 999 ? 57.581 49.745 -16.464 1.00 14.91 ? 999 VAL A CG1 1 ATOM 8101 C CG2 . VAL A 1 999 ? 58.120 48.004 -14.688 1.00 14.56 ? 999 VAL A CG2 1 ATOM 8102 N N . CYS A 1 1000 ? 61.280 46.964 -15.514 1.00 15.47 ? 1000 CYS A N 1 ATOM 8103 C CA . CYS A 1 1000 ? 62.469 46.604 -14.742 1.00 16.98 ? 1000 CYS A CA 1 ATOM 8104 C C . CYS A 1 1000 ? 63.806 46.812 -15.451 1.00 16.84 ? 1000 CYS A C 1 ATOM 8105 O O . CYS A 1 1000 ? 64.832 46.919 -14.789 1.00 18.56 ? 1000 CYS A O 1 ATOM 8106 C CB . CYS A 1 1000 ? 62.338 45.197 -14.153 1.00 17.83 ? 1000 CYS A CB 1 ATOM 8107 S SG . CYS A 1 1000 ? 61.359 45.224 -12.598 1.00 24.16 ? 1000 CYS A SG 1 ATOM 8108 N N . HIS A 1 1001 ? 63.766 46.951 -16.773 1.00 17.16 ? 1001 HIS A N 1 ATOM 8109 C CA . HIS A 1 1001 ? 64.970 47.231 -17.543 1.00 17.59 ? 1001 HIS A CA 1 ATOM 8110 C C . HIS A 1 1001 ? 65.043 48.676 -18.060 1.00 17.41 ? 1001 HIS A C 1 ATOM 8111 O O . HIS A 1 1001 ? 65.895 49.017 -18.886 1.00 18.10 ? 1001 HIS A O 1 ATOM 8112 C CB . HIS A 1 1001 ? 65.132 46.211 -18.674 1.00 18.05 ? 1001 HIS A CB 1 ATOM 8113 C CG . HIS A 1 1001 ? 65.687 44.902 -18.218 1.00 19.30 ? 1001 HIS A CG 1 ATOM 8114 N ND1 . HIS A 1 1001 ? 64.891 43.863 -17.790 1.00 20.23 ? 1001 HIS A ND1 1 ATOM 8115 C CD2 . HIS A 1 1001 ? 66.967 44.472 -18.091 1.00 21.62 ? 1001 HIS A CD2 1 ATOM 8116 C CE1 . HIS A 1 1001 ? 65.652 42.842 -17.431 1.00 20.23 ? 1001 HIS A CE1 1 ATOM 8117 N NE2 . HIS A 1 1001 ? 66.915 43.181 -17.618 1.00 21.30 ? 1001 HIS A NE2 1 ATOM 8118 N N . LEU A 1 1002 ? 64.165 49.549 -17.575 1.00 16.35 ? 1002 LEU A N 1 ATOM 8119 C CA . LEU A 1 1002 ? 64.256 50.962 -17.956 1.00 16.29 ? 1002 LEU A CA 1 ATOM 8120 C C . LEU A 1 1002 ? 65.502 51.653 -17.420 1.00 17.41 ? 1002 LEU A C 1 ATOM 8121 O O . LEU A 1 1002 ? 65.999 52.600 -18.034 1.00 18.99 ? 1002 LEU A O 1 ATOM 8122 C CB . LEU A 1 1002 ? 63.011 51.731 -17.478 1.00 15.97 ? 1002 LEU A CB 1 ATOM 8123 C CG . LEU A 1 1002 ? 61.776 51.605 -18.352 1.00 14.73 ? 1002 LEU A CG 1 ATOM 8124 C CD1 . LEU A 1 1002 ? 60.561 52.240 -17.656 1.00 14.49 ? 1002 LEU A CD1 1 ATOM 8125 C CD2 . LEU A 1 1002 ? 62.029 52.300 -19.698 1.00 17.87 ? 1002 LEU A CD2 1 ATOM 8126 N N . LEU A 1 1003 ? 65.981 51.222 -16.259 1.00 17.46 ? 1003 LEU A N 1 ATOM 8127 C CA . LEU A 1 1003 ? 67.228 51.743 -15.712 1.00 18.06 ? 1003 LEU A CA 1 ATOM 8128 C C . LEU A 1 1003 ? 68.298 50.651 -15.824 1.00 18.30 ? 1003 LEU A C 1 ATOM 8129 O O . LEU A 1 1003 ? 67.988 49.478 -15.686 1.00 17.99 ? 1003 LEU A O 1 ATOM 8130 C CB . LEU A 1 1003 ? 67.085 52.191 -14.257 1.00 17.87 ? 1003 LEU A CB 1 ATOM 8131 C CG . LEU A 1 1003 ? 66.485 53.594 -14.026 1.00 21.37 ? 1003 LEU A CG 1 ATOM 8132 C CD1 . LEU A 1 1003 ? 65.025 53.700 -14.393 1.00 26.18 ? 1003 LEU A CD1 1 ATOM 8133 C CD2 . LEU A 1 1003 ? 66.671 53.999 -12.601 1.00 26.13 ? 1003 LEU A CD2 1 ATOM 8134 N N . PRO A 1 1004 ? 69.553 51.031 -16.034 1.00 19.05 ? 1004 PRO A N 1 ATOM 8135 C CA . PRO A 1 1004 ? 70.609 50.031 -16.237 1.00 18.87 ? 1004 PRO A CA 1 ATOM 8136 C C . PRO A 1 1004 ? 70.980 49.304 -14.944 1.00 19.16 ? 1004 PRO A C 1 ATOM 8137 O O . PRO A 1 1004 ? 70.615 49.693 -13.806 1.00 17.73 ? 1004 PRO A O 1 ATOM 8138 C CB . PRO A 1 1004 ? 71.778 50.870 -16.746 1.00 19.31 ? 1004 PRO A CB 1 ATOM 8139 C CG . PRO A 1 1004 ? 71.579 52.197 -16.125 1.00 19.71 ? 1004 PRO A CG 1 ATOM 8140 C CD . PRO A 1 1004 ? 70.074 52.411 -16.067 1.00 18.74 ? 1004 PRO A CD 1 ATOM 8141 N N . ASN A 1 1005 ? 71.719 48.206 -15.132 1.00 19.09 ? 1005 ASN A N 1 ATOM 8142 C CA . ASN A 1 1005 ? 72.291 47.445 -14.007 1.00 19.64 ? 1005 ASN A CA 1 ATOM 8143 C C . ASN A 1 1005 ? 71.250 46.882 -13.046 1.00 18.51 ? 1005 ASN A C 1 ATOM 8144 O O . ASN A 1 1005 ? 71.438 46.919 -11.832 1.00 19.10 ? 1005 ASN A O 1 ATOM 8145 C CB . ASN A 1 1005 ? 73.292 48.291 -13.204 1.00 20.54 ? 1005 ASN A CB 1 ATOM 8146 C CG . ASN A 1 1005 ? 74.264 49.047 -14.082 1.00 24.50 ? 1005 ASN A CG 1 ATOM 8147 O OD1 . ASN A 1 1005 ? 74.355 50.277 -14.010 1.00 29.67 ? 1005 ASN A OD1 1 ATOM 8148 N ND2 . ASN A 1 1005 ? 74.969 48.328 -14.931 1.00 26.01 ? 1005 ASN A ND2 1 ATOM 8149 N N . VAL A 1 1006 ? 70.157 46.378 -13.611 1.00 19.06 ? 1006 VAL A N 1 ATOM 8150 C CA . VAL A 1 1006 ? 69.116 45.776 -12.799 1.00 18.80 ? 1006 VAL A CA 1 ATOM 8151 C C . VAL A 1 1006 ? 69.690 44.496 -12.164 1.00 19.35 ? 1006 VAL A C 1 ATOM 8152 O O . VAL A 1 1006 ? 70.347 43.689 -12.841 1.00 20.83 ? 1006 VAL A O 1 ATOM 8153 C CB . VAL A 1 1006 ? 67.782 45.543 -13.586 1.00 18.71 ? 1006 VAL A CB 1 ATOM 8154 C CG1 . VAL A 1 1006 ? 67.933 44.539 -14.669 1.00 20.11 ? 1006 VAL A CG1 1 ATOM 8155 C CG2 . VAL A 1 1006 ? 66.652 45.107 -12.645 1.00 18.76 ? 1006 VAL A CG2 1 ATOM 8156 N N . ALA A 1 1007 ? 69.448 44.360 -10.867 1.00 18.52 ? 1007 ALA A N 1 ATOM 8157 C CA . ALA A 1 1007 ? 69.898 43.210 -10.068 1.00 18.94 ? 1007 ALA A CA 1 ATOM 8158 C C . ALA A 1 1007 ? 68.727 42.361 -9.591 1.00 19.68 ? 1007 ALA A C 1 ATOM 8159 O O . ALA A 1 1007 ? 68.908 41.195 -9.238 1.00 19.70 ? 1007 ALA A O 1 ATOM 8160 C CB . ALA A 1 1007 ? 70.723 43.688 -8.877 1.00 19.31 ? 1007 ALA A CB 1 ATOM 8161 N N . ARG A 1 1008 ? 67.514 42.930 -9.562 1.00 18.66 ? 1008 ARG A N 1 ATOM 8162 C CA . ARG A 1 1008 ? 66.349 42.213 -9.079 1.00 18.55 ? 1008 ARG A CA 1 ATOM 8163 C C . ARG A 1 1008 ? 65.102 42.947 -9.550 1.00 16.63 ? 1008 ARG A C 1 ATOM 8164 O O . ARG A 1 1008 ? 65.130 44.176 -9.714 1.00 16.16 ? 1008 ARG A O 1 ATOM 8165 C CB . ARG A 1 1008 ? 66.375 42.209 -7.547 1.00 18.50 ? 1008 ARG A CB 1 ATOM 8166 C CG . ARG A 1 1008 ? 65.399 41.287 -6.869 1.00 21.83 ? 1008 ARG A CG 1 ATOM 8167 C CD . ARG A 1 1008 ? 65.483 41.360 -5.353 1.00 22.80 ? 1008 ARG A CD 1 ATOM 8168 N NE . ARG A 1 1008 ? 64.716 40.284 -4.735 1.00 31.30 ? 1008 ARG A NE 1 ATOM 8169 C CZ . ARG A 1 1008 ? 65.173 39.050 -4.526 1.00 34.16 ? 1008 ARG A CZ 1 ATOM 8170 N NH1 . ARG A 1 1008 ? 66.417 38.721 -4.877 1.00 36.10 ? 1008 ARG A NH1 1 ATOM 8171 N NH2 . ARG A 1 1008 ? 64.382 38.137 -3.970 1.00 34.36 ? 1008 ARG A NH2 1 ATOM 8172 N N . CYS A 1 1009 ? 64.028 42.208 -9.764 1.00 16.75 ? 1009 CYS A N 1 ATOM 8173 C CA . CYS A 1 1009 ? 62.728 42.814 -10.115 1.00 16.75 ? 1009 CYS A CA 1 ATOM 8174 C C . CYS A 1 1009 ? 61.676 42.079 -9.305 1.00 16.06 ? 1009 CYS A C 1 ATOM 8175 O O . CYS A 1 1009 ? 61.624 40.847 -9.311 1.00 16.15 ? 1009 CYS A O 1 ATOM 8176 C CB . CYS A 1 1009 ? 62.464 42.651 -11.605 1.00 17.08 ? 1009 CYS A CB 1 ATOM 8177 S SG . CYS A 1 1009 ? 60.902 43.312 -12.235 1.00 22.99 ? 1009 CYS A SG 1 ATOM 8178 N N . GLU A 1 1010 ? 60.842 42.817 -8.578 1.00 14.44 ? 1010 GLU A N 1 ATOM 8179 C CA . GLU A 1 1010 ? 59.823 42.210 -7.754 1.00 14.03 ? 1010 GLU A CA 1 ATOM 8180 C C . GLU A 1 1010 ? 58.464 42.824 -8.077 1.00 12.64 ? 1010 GLU A C 1 ATOM 8181 O O . GLU A 1 1010 ? 58.352 44.042 -8.312 1.00 12.99 ? 1010 GLU A O 1 ATOM 8182 C CB . GLU A 1 1010 ? 60.156 42.445 -6.280 1.00 15.64 ? 1010 GLU A CB 1 ATOM 8183 C CG . GLU A 1 1010 ? 61.384 41.639 -5.846 1.00 20.67 ? 1010 GLU A CG 1 ATOM 8184 C CD . GLU A 1 1010 ? 62.158 42.219 -4.668 1.00 26.13 ? 1010 GLU A CD 1 ATOM 8185 O OE1 . GLU A 1 1010 ? 62.554 43.418 -4.671 1.00 26.25 ? 1010 GLU A OE1 1 ATOM 8186 O OE2 . GLU A 1 1010 ? 62.420 41.429 -3.726 1.00 29.66 ? 1010 GLU A OE2 1 ATOM 8187 N N . ARG A 1 1011 ? 57.437 42.011 -8.064 1.00 12.36 ? 1011 ARG A N 1 ATOM 8188 C CA . ARG A 1 1011 ? 56.067 42.547 -8.031 1.00 11.75 ? 1011 ARG A CA 1 ATOM 8189 C C . ARG A 1 1011 ? 55.743 42.883 -6.577 1.00 11.95 ? 1011 ARG A C 1 ATOM 8190 O O . ARG A 1 1011 ? 56.060 42.104 -5.659 1.00 12.05 ? 1011 ARG A O 1 ATOM 8191 C CB . ARG A 1 1011 ? 55.073 41.542 -8.567 1.00 12.96 ? 1011 ARG A CB 1 ATOM 8192 C CG . ARG A 1 1011 ? 53.696 42.182 -8.861 1.00 16.01 ? 1011 ARG A CG 1 ATOM 8193 C CD . ARG A 1 1011 ? 52.751 41.265 -9.557 1.00 19.70 ? 1011 ARG A CD 1 ATOM 8194 N NE . ARG A 1 1011 ? 52.495 40.086 -8.737 1.00 26.97 ? 1011 ARG A NE 1 ATOM 8195 C CZ . ARG A 1 1011 ? 51.517 39.982 -7.837 1.00 29.89 ? 1011 ARG A CZ 1 ATOM 8196 N NH1 . ARG A 1 1011 ? 50.677 40.994 -7.625 1.00 33.21 ? 1011 ARG A NH1 1 ATOM 8197 N NH2 . ARG A 1 1011 ? 51.376 38.853 -7.148 1.00 32.02 ? 1011 ARG A NH2 1 ATOM 8198 N N . THR A 1 1012 ? 55.125 44.044 -6.327 1.00 10.66 ? 1012 THR A N 1 ATOM 8199 C CA . THR A 1 1012 ? 54.810 44.485 -4.978 1.00 9.12 ? 1012 THR A CA 1 ATOM 8200 C C . THR A 1 1012 ? 53.326 44.866 -4.895 1.00 9.60 ? 1012 THR A C 1 ATOM 8201 O O . THR A 1 1012 ? 52.639 45.034 -5.920 1.00 9.80 ? 1012 THR A O 1 ATOM 8202 C CB . THR A 1 1012 ? 55.670 45.686 -4.562 1.00 10.18 ? 1012 THR A CB 1 ATOM 8203 O OG1 . THR A 1 1012 ? 55.357 46.810 -5.415 1.00 10.89 ? 1012 THR A OG1 1 ATOM 8204 C CG2 . THR A 1 1012 ? 57.139 45.401 -4.766 1.00 10.80 ? 1012 THR A CG2 1 ATOM 8205 N N . THR A 1 1013 ? 52.854 45.064 -3.668 1.00 9.18 ? 1013 THR A N 1 ATOM 8206 C CA . THR A 1 1013 ? 51.608 45.802 -3.488 1.00 9.59 ? 1013 THR A CA 1 ATOM 8207 C C . THR A 1 1013 ? 51.725 47.190 -4.109 1.00 8.26 ? 1013 THR A C 1 ATOM 8208 O O . THR A 1 1013 ? 52.808 47.710 -4.379 1.00 7.97 ? 1013 THR A O 1 ATOM 8209 C CB . THR A 1 1013 ? 51.269 45.938 -2.024 1.00 9.10 ? 1013 THR A CB 1 ATOM 8210 O OG1 . THR A 1 1013 ? 52.456 46.350 -1.327 1.00 9.49 ? 1013 THR A OG1 1 ATOM 8211 C CG2 . THR A 1 1013 ? 50.849 44.562 -1.415 1.00 11.32 ? 1013 THR A CG2 1 ATOM 8212 N N . LEU A 1 1014 ? 50.563 47.829 -4.327 1.00 8.03 ? 1014 LEU A N 1 ATOM 8213 C CA . LEU A 1 1014 ? 50.579 49.098 -5.085 1.00 7.51 ? 1014 LEU A CA 1 ATOM 8214 C C . LEU A 1 1014 ? 51.246 50.245 -4.353 1.00 6.86 ? 1014 LEU A C 1 ATOM 8215 O O . LEU A 1 1014 ? 51.613 51.252 -4.956 1.00 7.50 ? 1014 LEU A O 1 ATOM 8216 C CB . LEU A 1 1014 ? 49.164 49.543 -5.485 1.00 7.72 ? 1014 LEU A CB 1 ATOM 8217 C CG . LEU A 1 1014 ? 48.368 48.596 -6.379 1.00 7.97 ? 1014 LEU A CG 1 ATOM 8218 C CD1 . LEU A 1 1014 ? 47.056 49.258 -6.753 1.00 8.15 ? 1014 LEU A CD1 1 ATOM 8219 C CD2 . LEU A 1 1014 ? 49.181 48.248 -7.642 1.00 8.36 ? 1014 LEU A CD2 1 ATOM 8220 N N . THR A 1 1015 ? 51.391 50.110 -3.030 1.00 6.77 ? 1015 THR A N 1 ATOM 8221 C CA . THR A 1 1015 ? 52.086 51.072 -2.167 1.00 7.38 ? 1015 THR A CA 1 ATOM 8222 C C . THR A 1 1015 ? 53.587 50.832 -2.116 1.00 7.32 ? 1015 THR A C 1 ATOM 8223 O O . THR A 1 1015 ? 54.283 51.600 -1.471 1.00 8.67 ? 1015 THR A O 1 ATOM 8224 C CB . THR A 1 1015 ? 51.597 50.951 -0.747 1.00 8.40 ? 1015 THR A CB 1 ATOM 8225 O OG1 . THR A 1 1015 ? 51.735 49.563 -0.385 1.00 7.94 ? 1015 THR A OG1 1 ATOM 8226 C CG2 . THR A 1 1015 ? 50.086 51.306 -0.640 1.00 8.96 ? 1015 THR A CG2 1 ATOM 8227 N N . PHE A 1 1016 ? 54.052 49.772 -2.776 1.00 7.67 ? 1016 PHE A N 1 ATOM 8228 C CA . PHE A 1 1016 ? 55.460 49.330 -2.834 1.00 9.21 ? 1016 PHE A CA 1 ATOM 8229 C C . PHE A 1 1016 ? 55.923 48.736 -1.509 1.00 10.02 ? 1016 PHE A C 1 ATOM 8230 O O . PHE A 1 1016 ? 57.123 48.453 -1.375 1.00 11.23 ? 1016 PHE A O 1 ATOM 8231 C CB . PHE A 1 1016 ? 56.430 50.431 -3.287 1.00 9.71 ? 1016 PHE A CB 1 ATOM 8232 C CG . PHE A 1 1016 ? 56.071 51.075 -4.601 1.00 8.54 ? 1016 PHE A CG 1 ATOM 8233 C CD1 . PHE A 1 1016 ? 55.958 50.308 -5.751 1.00 9.50 ? 1016 PHE A CD1 1 ATOM 8234 C CD2 . PHE A 1 1016 ? 55.890 52.465 -4.677 1.00 9.68 ? 1016 PHE A CD2 1 ATOM 8235 C CE1 . PHE A 1 1016 ? 55.643 50.942 -6.975 1.00 9.57 ? 1016 PHE A CE1 1 ATOM 8236 C CE2 . PHE A 1 1016 ? 55.588 53.068 -5.889 1.00 8.67 ? 1016 PHE A CE2 1 ATOM 8237 C CZ . PHE A 1 1016 ? 55.480 52.280 -7.035 1.00 10.21 ? 1016 PHE A CZ 1 ATOM 8238 N N . LEU A 1 1017 ? 55.032 48.490 -0.546 1.00 9.65 ? 1017 LEU A N 1 ATOM 8239 C CA . LEU A 1 1017 ? 55.485 48.159 0.820 1.00 11.28 ? 1017 LEU A CA 1 ATOM 8240 C C . LEU A 1 1017 ? 55.675 46.675 1.079 1.00 12.48 ? 1017 LEU A C 1 ATOM 8241 O O . LEU A 1 1017 ? 56.271 46.323 2.113 1.00 15.15 ? 1017 LEU A O 1 ATOM 8242 C CB . LEU A 1 1017 ? 54.527 48.779 1.826 1.00 11.03 ? 1017 LEU A CB 1 ATOM 8243 C CG . LEU A 1 1017 ? 54.531 50.300 1.775 1.00 10.47 ? 1017 LEU A CG 1 ATOM 8244 C CD1 . LEU A 1 1017 ? 53.465 50.819 2.724 1.00 10.85 ? 1017 LEU A CD1 1 ATOM 8245 C CD2 . LEU A 1 1017 ? 55.872 50.909 2.094 1.00 12.70 ? 1017 LEU A CD2 1 ATOM 8246 N N . GLN A 1 1018 ? 55.178 45.801 0.208 1.00 11.06 ? 1018 GLN A N 1 ATOM 8247 C CA . GLN A 1 1018 ? 55.346 44.342 0.392 1.00 13.34 ? 1018 GLN A CA 1 ATOM 8248 C C . GLN A 1 1018 ? 55.697 43.696 -0.925 1.00 13.08 ? 1018 GLN A C 1 ATOM 8249 O O . GLN A 1 1018 ? 55.046 43.972 -1.925 1.00 12.81 ? 1018 GLN A O 1 ATOM 8250 C CB . GLN A 1 1018 ? 54.063 43.704 0.929 1.00 13.69 ? 1018 GLN A CB 1 ATOM 8251 C CG . GLN A 1 1018 ? 54.245 42.195 1.199 1.00 17.23 ? 1018 GLN A CG 1 ATOM 8252 C CD . GLN A 1 1018 ? 52.962 41.429 1.433 1.00 19.23 ? 1018 GLN A CD 1 ATOM 8253 O OE1 . GLN A 1 1018 ? 51.869 42.005 1.526 1.00 22.54 ? 1018 GLN A OE1 1 ATOM 8254 N NE2 . GLN A 1 1018 ? 53.090 40.097 1.535 1.00 22.30 ? 1018 GLN A NE2 1 ATOM 8255 N N . ASN A 1 1019 ? 56.723 42.838 -0.918 1.00 14.03 ? 1019 ASN A N 1 ATOM 8256 C CA . ASN A 1 1019 ? 57.114 42.088 -2.092 1.00 16.09 ? 1019 ASN A CA 1 ATOM 8257 C C . ASN A 1 1019 ? 56.208 40.889 -2.214 1.00 17.05 ? 1019 ASN A C 1 ATOM 8258 O O . ASN A 1 1019 ? 56.023 40.143 -1.235 1.00 18.47 ? 1019 ASN A O 1 ATOM 8259 C CB . ASN A 1 1019 ? 58.590 41.648 -1.990 1.00 16.40 ? 1019 ASN A CB 1 ATOM 8260 C CG . ASN A 1 1019 ? 59.554 42.835 -1.874 1.00 19.00 ? 1019 ASN A CG 1 ATOM 8261 O OD1 . ASN A 1 1019 ? 59.329 43.891 -2.476 1.00 20.91 ? 1019 ASN A OD1 1 ATOM 8262 N ND2 . ASN A 1 1019 ? 60.646 42.664 -1.104 1.00 21.75 ? 1019 ASN A ND2 1 ATOM 8263 N N . LEU A 1 1020 ? 55.622 40.698 -3.383 1.00 16.99 ? 1020 LEU A N 1 ATOM 8264 C CA . LEU A 1 1020 ? 54.682 39.624 -3.632 1.00 18.53 ? 1020 LEU A CA 1 ATOM 8265 C C . LEU A 1 1020 ? 55.274 38.514 -4.486 1.00 19.89 ? 1020 LEU A C 1 ATOM 8266 O O . LEU A 1 1020 ? 54.835 37.361 -4.385 1.00 20.73 ? 1020 LEU A O 1 ATOM 8267 C CB . LEU A 1 1020 ? 53.412 40.150 -4.300 1.00 18.83 ? 1020 LEU A CB 1 ATOM 8268 C CG . LEU A 1 1020 ? 52.643 41.225 -3.523 1.00 17.47 ? 1020 LEU A CG 1 ATOM 8269 C CD1 . LEU A 1 1020 ? 51.504 41.714 -4.423 1.00 19.89 ? 1020 LEU A CD1 1 ATOM 8270 C CD2 . LEU A 1 1020 ? 52.116 40.692 -2.184 1.00 19.01 ? 1020 LEU A CD2 1 ATOM 8271 N N . GLU A 1 1021 ? 56.246 38.845 -5.330 1.00 20.55 ? 1021 GLU A N 1 ATOM 8272 C CA . GLU A 1 1021 ? 56.811 37.871 -6.279 1.00 23.03 ? 1021 GLU A CA 1 ATOM 8273 C C . GLU A 1 1021 ? 58.175 38.317 -6.761 1.00 22.46 ? 1021 GLU A C 1 ATOM 8274 O O . GLU A 1 1021 ? 58.365 39.469 -7.158 1.00 20.42 ? 1021 GLU A O 1 ATOM 8275 C CB . GLU A 1 1021 ? 55.876 37.696 -7.483 1.00 22.60 ? 1021 GLU A CB 1 ATOM 8276 C CG . GLU A 1 1021 ? 56.319 36.651 -8.507 1.00 26.83 ? 1021 GLU A CG 1 ATOM 8277 C CD . GLU A 1 1021 ? 55.432 36.610 -9.740 1.00 27.67 ? 1021 GLU A CD 1 ATOM 8278 O OE1 . GLU A 1 1021 ? 54.421 37.366 -9.810 1.00 33.21 ? 1021 GLU A OE1 1 ATOM 8279 O OE2 . GLU A 1 1021 ? 55.765 35.817 -10.663 1.00 34.00 ? 1021 GLU A OE2 1 ATOM 8280 N N . HIS A 1 1022 ? 59.122 37.397 -6.747 1.00 22.98 ? 1022 HIS A N 1 ATOM 8281 C CA . HIS A 1 1022 ? 60.441 37.646 -7.258 1.00 23.68 ? 1022 HIS A CA 1 ATOM 8282 C C . HIS A 1 1022 ? 60.445 37.202 -8.703 1.00 23.93 ? 1022 HIS A C 1 ATOM 8283 O O . HIS A 1 1022 ? 60.087 36.079 -9.010 1.00 23.84 ? 1022 HIS A O 1 ATOM 8284 C CB . HIS A 1 1022 ? 61.439 36.832 -6.432 1.00 24.43 ? 1022 HIS A CB 1 ATOM 8285 C CG . HIS A 1 1022 ? 62.864 37.042 -6.819 1.00 28.07 ? 1022 HIS A CG 1 ATOM 8286 N ND1 . HIS A 1 1022 ? 63.821 36.065 -6.652 1.00 31.69 ? 1022 HIS A ND1 1 ATOM 8287 C CD2 . HIS A 1 1022 ? 63.506 38.113 -7.339 1.00 31.15 ? 1022 HIS A CD2 1 ATOM 8288 C CE1 . HIS A 1 1022 ? 64.986 36.515 -7.083 1.00 32.84 ? 1022 HIS A CE1 1 ATOM 8289 N NE2 . HIS A 1 1022 ? 64.825 37.757 -7.496 1.00 33.30 ? 1022 HIS A NE2 1 ATOM 8290 N N . LEU A 1 1023 ? 60.802 38.095 -9.607 1.00 23.41 ? 1023 LEU A N 1 ATOM 8291 C CA . LEU A 1 1023 ? 60.494 37.862 -11.006 1.00 24.27 ? 1023 LEU A CA 1 ATOM 8292 C C . LEU A 1 1023 ? 61.651 37.260 -11.792 1.00 25.26 ? 1023 LEU A C 1 ATOM 8293 O O . LEU A 1 1023 ? 62.774 37.768 -11.742 1.00 24.81 ? 1023 LEU A O 1 ATOM 8294 C CB . LEU A 1 1023 ? 59.993 39.147 -11.664 1.00 23.78 ? 1023 LEU A CB 1 ATOM 8295 C CG . LEU A 1 1023 ? 58.621 39.600 -11.158 1.00 23.26 ? 1023 LEU A CG 1 ATOM 8296 C CD1 . LEU A 1 1023 ? 58.402 41.071 -11.457 1.00 24.12 ? 1023 LEU A CD1 1 ATOM 8297 C CD2 . LEU A 1 1023 ? 57.512 38.748 -11.760 1.00 25.16 ? 1023 LEU A CD2 1 ATOM 8298 N N . ASP A 1 1024 ? 61.336 36.193 -12.529 1.00 27.63 ? 1024 ASP A N 1 ATOM 8299 C CA . ASP A 1 1024 ? 62.309 35.478 -13.360 1.00 29.34 ? 1024 ASP A CA 1 ATOM 8300 C C . ASP A 1 1024 ? 62.858 36.349 -14.463 1.00 29.24 ? 1024 ASP A C 1 ATOM 8301 O O . ASP A 1 1024 ? 62.099 37.040 -15.166 1.00 29.62 ? 1024 ASP A O 1 ATOM 8302 C CB . ASP A 1 1024 ? 61.666 34.244 -13.996 1.00 30.41 ? 1024 ASP A CB 1 ATOM 8303 C CG . ASP A 1 1024 ? 61.199 33.228 -12.966 1.00 34.23 ? 1024 ASP A CG 1 ATOM 8304 O OD1 . ASP A 1 1024 ? 61.780 33.193 -11.852 1.00 38.73 ? 1024 ASP A OD1 1 ATOM 8305 O OD2 . ASP A 1 1024 ? 60.259 32.419 -13.191 1.00 38.45 ? 1024 ASP A OD2 1 ATOM 8306 N N . GLY A 1 1025 ? 64.178 36.311 -14.609 1.00 28.45 ? 1025 GLY A N 1 ATOM 8307 C CA . GLY A 1 1025 ? 64.873 37.069 -15.630 1.00 28.30 ? 1025 GLY A CA 1 ATOM 8308 C C . GLY A 1 1025 ? 64.883 38.556 -15.365 1.00 27.40 ? 1025 GLY A C 1 ATOM 8309 O O . GLY A 1 1025 ? 65.355 39.317 -16.198 1.00 27.82 ? 1025 GLY A O 1 ATOM 8310 N N . MET A 1 1026 ? 64.368 38.965 -14.202 1.00 26.81 ? 1026 MET A N 1 ATOM 8311 C CA . MET A 1 1026 ? 64.235 40.386 -13.854 1.00 26.84 ? 1026 MET A CA 1 ATOM 8312 C C . MET A 1 1026 ? 63.335 41.096 -14.859 1.00 25.68 ? 1026 MET A C 1 ATOM 8313 O O . MET A 1 1026 ? 63.562 42.268 -15.196 1.00 25.61 ? 1026 MET A O 1 ATOM 8314 C CB . MET A 1 1026 ? 65.604 41.075 -13.762 1.00 26.39 ? 1026 MET A CB 1 ATOM 8315 C CG . MET A 1 1026 ? 66.529 40.463 -12.710 1.00 27.62 ? 1026 MET A CG 1 ATOM 8316 S SD . MET A 1 1026 ? 68.182 41.168 -12.676 1.00 30.27 ? 1026 MET A SD 1 ATOM 8317 C CE . MET A 1 1026 ? 68.852 40.603 -14.278 1.00 32.41 ? 1026 MET A CE 1 ATOM 8318 N N . VAL A 1 1027 ? 62.333 40.377 -15.356 1.00 24.60 ? 1027 VAL A N 1 ATOM 8319 C CA . VAL A 1 1027 ? 61.414 40.932 -16.342 1.00 25.08 ? 1027 VAL A CA 1 ATOM 8320 C C . VAL A 1 1027 ? 60.040 41.154 -15.709 1.00 25.27 ? 1027 VAL A C 1 ATOM 8321 O O . VAL A 1 1027 ? 59.434 40.226 -15.157 1.00 25.13 ? 1027 VAL A O 1 ATOM 8322 C CB . VAL A 1 1027 ? 61.307 40.046 -17.603 1.00 24.76 ? 1027 VAL A CB 1 ATOM 8323 C CG1 . VAL A 1 1027 ? 60.136 40.477 -18.481 1.00 25.18 ? 1027 VAL A CG1 1 ATOM 8324 C CG2 . VAL A 1 1027 ? 62.626 40.085 -18.405 1.00 25.82 ? 1027 VAL A CG2 1 ATOM 8325 N N . ALA A 1 1028 ? 59.561 42.393 -15.782 1.00 25.06 ? 1028 ALA A N 1 ATOM 8326 C CA . ALA A 1 1028 ? 58.230 42.731 -15.279 1.00 25.73 ? 1028 ALA A CA 1 ATOM 8327 C C . ALA A 1 1028 ? 57.232 42.504 -16.390 1.00 26.13 ? 1028 ALA A C 1 ATOM 8328 O O . ALA A 1 1028 ? 57.274 43.220 -17.397 1.00 26.64 ? 1028 ALA A O 1 ATOM 8329 C CB . ALA A 1 1028 ? 58.181 44.184 -14.826 1.00 25.23 ? 1028 ALA A CB 1 ATOM 8330 N N . PRO A 1 1029 ? 56.331 41.538 -16.211 1.00 25.95 ? 1029 PRO A N 1 ATOM 8331 C CA . PRO A 1 1029 ? 55.312 41.248 -17.228 1.00 26.59 ? 1029 PRO A CA 1 ATOM 8332 C C . PRO A 1 1029 ? 54.288 42.374 -17.304 1.00 26.34 ? 1029 PRO A C 1 ATOM 8333 O O . PRO A 1 1029 ? 54.029 43.030 -16.305 1.00 27.85 ? 1029 PRO A O 1 ATOM 8334 C CB . PRO A 1 1029 ? 54.629 39.977 -16.709 1.00 26.46 ? 1029 PRO A CB 1 ATOM 8335 C CG . PRO A 1 1029 ? 55.411 39.522 -15.509 1.00 26.75 ? 1029 PRO A CG 1 ATOM 8336 C CD . PRO A 1 1029 ? 56.195 40.683 -15.017 1.00 25.98 ? 1029 PRO A CD 1 ATOM 8337 N N . GLU A 1 1030 ? 53.736 42.607 -18.481 1.00 26.11 ? 1030 GLU A N 1 ATOM 8338 C CA . GLU A 1 1030 ? 52.628 43.538 -18.622 1.00 25.66 ? 1030 GLU A CA 1 ATOM 8339 C C . GLU A 1 1030 ? 51.353 42.961 -17.987 1.00 25.01 ? 1030 GLU A C 1 ATOM 8340 O O . GLU A 1 1030 ? 51.203 41.733 -17.820 1.00 26.36 ? 1030 GLU A O 1 ATOM 8341 C CB . GLU A 1 1030 ? 52.390 43.861 -20.098 1.00 25.91 ? 1030 GLU A CB 1 ATOM 8342 C CG . GLU A 1 1030 ? 53.511 44.653 -20.774 1.00 25.10 ? 1030 GLU A CG 1 ATOM 8343 C CD . GLU A 1 1030 ? 53.194 44.992 -22.223 1.00 26.23 ? 1030 GLU A CD 1 ATOM 8344 O OE1 . GLU A 1 1030 ? 52.235 44.398 -22.783 1.00 29.14 ? 1030 GLU A OE1 1 ATOM 8345 O OE2 . GLU A 1 1030 ? 53.915 45.842 -22.807 1.00 23.28 ? 1030 GLU A OE2 1 ATOM 8346 N N . VAL A 1 1031 ? 50.439 43.858 -17.639 1.00 23.25 ? 1031 VAL A N 1 ATOM 8347 C CA . VAL A 1 1031 ? 49.240 43.492 -16.899 1.00 20.46 ? 1031 VAL A CA 1 ATOM 8348 C C . VAL A 1 1031 ? 48.061 43.223 -17.839 1.00 19.19 ? 1031 VAL A C 1 ATOM 8349 O O . VAL A 1 1031 ? 48.099 43.597 -19.007 1.00 18.72 ? 1031 VAL A O 1 ATOM 8350 C CB . VAL A 1 1031 ? 48.904 44.568 -15.822 1.00 21.24 ? 1031 VAL A CB 1 ATOM 8351 C CG1 . VAL A 1 1031 ? 50.095 44.735 -14.868 1.00 23.16 ? 1031 VAL A CG1 1 ATOM 8352 C CG2 . VAL A 1 1031 ? 48.517 45.890 -16.436 1.00 21.71 ? 1031 VAL A CG2 1 ATOM 8353 N N . CYS A 1 1032 ? 47.040 42.544 -17.329 1.00 16.28 ? 1032 CYS A N 1 ATOM 8354 C CA . CYS A 1 1032 ? 45.785 42.286 -18.042 1.00 16.01 ? 1032 CYS A CA 1 ATOM 8355 C C . CYS A 1 1032 ? 44.881 43.529 -18.130 1.00 13.87 ? 1032 CYS A C 1 ATOM 8356 O O . CYS A 1 1032 ? 45.006 44.445 -17.317 1.00 12.69 ? 1032 CYS A O 1 ATOM 8357 C CB . CYS A 1 1032 ? 45.028 41.195 -17.312 1.00 15.67 ? 1032 CYS A CB 1 ATOM 8358 S SG . CYS A 1 1032 ? 45.839 39.588 -17.512 1.00 24.16 ? 1032 CYS A SG 1 ATOM 8359 N N . PRO A 1 1033 ? 43.950 43.564 -19.087 1.00 12.95 ? 1033 PRO A N 1 ATOM 8360 C CA . PRO A 1 1033 ? 42.974 44.663 -19.143 1.00 12.20 ? 1033 PRO A CA 1 ATOM 8361 C C . PRO A 1 1033 ? 42.247 44.832 -17.805 1.00 11.17 ? 1033 PRO A C 1 ATOM 8362 O O . PRO A 1 1033 ? 41.780 43.860 -17.188 1.00 11.41 ? 1033 PRO A O 1 ATOM 8363 C CB . PRO A 1 1033 ? 41.992 44.217 -20.238 1.00 12.98 ? 1033 PRO A CB 1 ATOM 8364 C CG . PRO A 1 1033 ? 42.853 43.386 -21.136 1.00 14.06 ? 1033 PRO A CG 1 ATOM 8365 C CD . PRO A 1 1033 ? 43.781 42.614 -20.220 1.00 14.03 ? 1033 PRO A CD 1 ATOM 8366 N N . MET A 1 1034 ? 42.153 46.097 -17.397 1.00 10.55 ? 1034 MET A N 1 ATOM 8367 C CA . MET A 1 1034 ? 41.546 46.545 -16.130 1.00 10.88 ? 1034 MET A CA 1 ATOM 8368 C C . MET A 1 1034 ? 42.353 46.186 -14.880 1.00 12.14 ? 1034 MET A C 1 ATOM 8369 O O . MET A 1 1034 ? 41.878 46.378 -13.755 1.00 15.96 ? 1034 MET A O 1 ATOM 8370 C CB . MET A 1 1034 ? 40.058 46.152 -15.976 1.00 9.90 ? 1034 MET A CB 1 ATOM 8371 C CG . MET A 1 1034 ? 39.182 46.655 -17.101 1.00 11.85 ? 1034 MET A CG 1 ATOM 8372 S SD . MET A 1 1034 ? 39.233 48.450 -17.320 1.00 12.76 ? 1034 MET A SD 1 ATOM 8373 C CE . MET A 1 1034 ? 38.396 48.983 -15.802 1.00 14.33 ? 1034 MET A CE 1 ATOM 8374 N N . GLU A 1 1035 ? 43.578 45.761 -15.064 1.00 10.81 ? 1035 GLU A N 1 ATOM 8375 C CA . GLU A 1 1035 ? 44.418 45.430 -13.915 1.00 11.63 ? 1035 GLU A CA 1 ATOM 8376 C C . GLU A 1 1035 ? 45.463 46.508 -13.713 1.00 10.66 ? 1035 GLU A C 1 ATOM 8377 O O . GLU A 1 1035 ? 45.830 47.230 -14.648 1.00 10.16 ? 1035 GLU A O 1 ATOM 8378 C CB . GLU A 1 1035 ? 45.040 44.049 -14.082 1.00 14.28 ? 1035 GLU A CB 1 ATOM 8379 C CG . GLU A 1 1035 ? 44.014 42.925 -13.888 1.00 21.12 ? 1035 GLU A CG 1 ATOM 8380 C CD . GLU A 1 1035 ? 43.625 42.730 -12.422 1.00 29.26 ? 1035 GLU A CD 1 ATOM 8381 O OE1 . GLU A 1 1035 ? 42.774 43.496 -11.897 1.00 31.98 ? 1035 GLU A OE1 1 ATOM 8382 O OE2 . GLU A 1 1035 ? 44.190 41.802 -11.790 1.00 35.64 ? 1035 GLU A OE2 1 ATOM 8383 N N . THR A 1 1036 ? 45.928 46.614 -12.469 1.00 10.31 ? 1036 THR A N 1 ATOM 8384 C CA . THR A 1 1036 ? 46.982 47.533 -12.065 1.00 10.69 ? 1036 THR A CA 1 ATOM 8385 C C . THR A 1 1036 ? 47.954 46.700 -11.260 1.00 11.15 ? 1036 THR A C 1 ATOM 8386 O O . THR A 1 1036 ? 47.525 45.935 -10.388 1.00 11.85 ? 1036 THR A O 1 ATOM 8387 C CB . THR A 1 1036 ? 46.383 48.638 -11.184 1.00 10.47 ? 1036 THR A CB 1 ATOM 8388 O OG1 . THR A 1 1036 ? 45.302 49.273 -11.873 1.00 11.11 ? 1036 THR A OG1 1 ATOM 8389 C CG2 . THR A 1 1036 ? 47.391 49.713 -10.830 1.00 11.61 ? 1036 THR A CG2 1 ATOM 8390 N N . ALA A 1 1037 ? 49.240 46.814 -11.565 1.00 10.08 ? 1037 ALA A N 1 ATOM 8391 C CA . ALA A 1 1037 ? 50.300 46.101 -10.858 1.00 10.37 ? 1037 ALA A CA 1 ATOM 8392 C C . ALA A 1 1037 ? 51.403 47.046 -10.521 1.00 10.37 ? 1037 ALA A C 1 ATOM 8393 O O . ALA A 1 1037 ? 51.547 48.095 -11.158 1.00 11.30 ? 1037 ALA A O 1 ATOM 8394 C CB . ALA A 1 1037 ? 50.847 44.977 -11.725 1.00 12.34 ? 1037 ALA A CB 1 ATOM 8395 N N . ALA A 1 1038 ? 52.170 46.695 -9.506 1.00 8.84 ? 1038 ALA A N 1 ATOM 8396 C CA . ALA A 1 1038 ? 53.329 47.469 -9.123 1.00 9.25 ? 1038 ALA A CA 1 ATOM 8397 C C . ALA A 1 1038 ? 54.574 46.605 -9.169 1.00 9.55 ? 1038 ALA A C 1 ATOM 8398 O O . ALA A 1 1038 ? 54.535 45.415 -8.811 1.00 9.74 ? 1038 ALA A O 1 ATOM 8399 C CB . ALA A 1 1038 ? 53.143 48.077 -7.740 1.00 9.24 ? 1038 ALA A CB 1 ATOM 8400 N N . TYR A 1 1039 ? 55.666 47.222 -9.581 1.00 9.71 ? 1039 TYR A N 1 ATOM 8401 C CA . TYR A 1 1039 ? 56.954 46.517 -9.627 1.00 10.81 ? 1039 TYR A CA 1 ATOM 8402 C C . TYR A 1 1039 ? 58.017 47.392 -9.052 1.00 11.42 ? 1039 TYR A C 1 ATOM 8403 O O . TYR A 1 1039 ? 57.936 48.614 -9.183 1.00 12.48 ? 1039 TYR A O 1 ATOM 8404 C CB . TYR A 1 1039 ? 57.321 46.181 -11.063 1.00 12.13 ? 1039 TYR A CB 1 ATOM 8405 C CG . TYR A 1 1039 ? 56.351 45.276 -11.764 1.00 12.28 ? 1039 TYR A CG 1 ATOM 8406 C CD1 . TYR A 1 1039 ? 56.338 43.899 -11.539 1.00 14.49 ? 1039 TYR A CD1 1 ATOM 8407 C CD2 . TYR A 1 1039 ? 55.402 45.807 -12.634 1.00 15.69 ? 1039 TYR A CD2 1 ATOM 8408 C CE1 . TYR A 1 1039 ? 55.414 43.081 -12.187 1.00 16.60 ? 1039 TYR A CE1 1 ATOM 8409 C CE2 . TYR A 1 1039 ? 54.501 44.997 -13.298 1.00 16.87 ? 1039 TYR A CE2 1 ATOM 8410 C CZ . TYR A 1 1039 ? 54.504 43.649 -13.060 1.00 17.89 ? 1039 TYR A CZ 1 ATOM 8411 O OH . TYR A 1 1039 ? 53.605 42.857 -13.747 1.00 20.11 ? 1039 TYR A OH 1 ATOM 8412 N N . VAL A 1 1040 ? 59.031 46.796 -8.412 1.00 11.46 ? 1040 VAL A N 1 ATOM 8413 C CA . VAL A 1 1040 ? 60.198 47.542 -7.954 1.00 12.13 ? 1040 VAL A CA 1 ATOM 8414 C C . VAL A 1 1040 ? 61.424 46.893 -8.566 1.00 12.09 ? 1040 VAL A C 1 ATOM 8415 O O . VAL A 1 1040 ? 61.618 45.656 -8.428 1.00 12.22 ? 1040 VAL A O 1 ATOM 8416 C CB . VAL A 1 1040 ? 60.303 47.539 -6.429 1.00 11.84 ? 1040 VAL A CB 1 ATOM 8417 C CG1 . VAL A 1 1040 ? 61.604 48.236 -5.985 1.00 12.80 ? 1040 VAL A CG1 1 ATOM 8418 C CG2 . VAL A 1 1040 ? 59.136 48.279 -5.825 1.00 12.19 ? 1040 VAL A CG2 1 ATOM 8419 N N . SER A 1 1041 ? 62.236 47.695 -9.251 1.00 11.49 ? 1041 SER A N 1 ATOM 8420 C CA . SER A 1 1041 ? 63.520 47.229 -9.758 1.00 12.49 ? 1041 SER A CA 1 ATOM 8421 C C . SER A 1 1041 ? 64.619 47.685 -8.828 1.00 12.98 ? 1041 SER A C 1 ATOM 8422 O O . SER A 1 1041 ? 64.605 48.808 -8.338 1.00 12.70 ? 1041 SER A O 1 ATOM 8423 C CB . SER A 1 1041 ? 63.738 47.720 -11.193 1.00 13.07 ? 1041 SER A CB 1 ATOM 8424 O OG . SER A 1 1041 ? 63.783 49.133 -11.305 1.00 13.63 ? 1041 SER A OG 1 ATOM 8425 N N . SER A 1 1042 ? 65.589 46.783 -8.602 1.00 14.00 ? 1042 SER A N 1 ATOM 8426 C CA . SER A 1 1042 ? 66.736 47.072 -7.759 1.00 14.67 ? 1042 SER A CA 1 ATOM 8427 C C . SER A 1 1042 ? 67.987 47.136 -8.640 1.00 15.11 ? 1042 SER A C 1 ATOM 8428 O O . SER A 1 1042 ? 68.117 46.336 -9.576 1.00 16.28 ? 1042 SER A O 1 ATOM 8429 C CB . SER A 1 1042 ? 66.919 45.985 -6.693 1.00 15.14 ? 1042 SER A CB 1 ATOM 8430 O OG . SER A 1 1042 ? 65.799 45.958 -5.830 1.00 16.65 ? 1042 SER A OG 1 ATOM 8431 N N . HIS A 1 1043 ? 68.855 48.103 -8.360 1.00 16.34 ? 1043 HIS A N 1 ATOM 8432 C CA . HIS A 1 1043 ? 70.004 48.387 -9.218 1.00 17.81 ? 1043 HIS A CA 1 ATOM 8433 C C . HIS A 1 1043 ? 71.270 48.519 -8.397 1.00 19.89 ? 1043 HIS A C 1 ATOM 8434 O O . HIS A 1 1043 ? 71.301 49.183 -7.361 1.00 18.49 ? 1043 HIS A O 1 ATOM 8435 C CB . HIS A 1 1043 ? 69.750 49.659 -10.051 1.00 17.46 ? 1043 HIS A CB 1 ATOM 8436 C CG . HIS A 1 1043 ? 68.448 49.614 -10.792 1.00 16.89 ? 1043 HIS A CG 1 ATOM 8437 N ND1 . HIS A 1 1043 ? 68.340 49.145 -12.085 1.00 16.33 ? 1043 HIS A ND1 1 ATOM 8438 C CD2 . HIS A 1 1043 ? 67.180 49.874 -10.378 1.00 13.94 ? 1043 HIS A CD2 1 ATOM 8439 C CE1 . HIS A 1 1043 ? 67.070 49.158 -12.452 1.00 16.27 ? 1043 HIS A CE1 1 ATOM 8440 N NE2 . HIS A 1 1043 ? 66.348 49.576 -11.421 1.00 14.03 ? 1043 HIS A NE2 1 ATOM 8441 N N . SER A 1 1044 ? 72.319 47.859 -8.886 1.00 23.66 ? 1044 SER A N 1 ATOM 8442 C CA . SER A 1 1044 ? 73.593 47.805 -8.169 1.00 28.04 ? 1044 SER A CA 1 ATOM 8443 C C . SER A 1 1044 ? 74.574 48.854 -8.678 1.00 30.48 ? 1044 SER A C 1 ATOM 8444 O O . SER A 1 1044 ? 75.604 49.104 -8.040 1.00 31.64 ? 1044 SER A O 1 ATOM 8445 C CB . SER A 1 1044 ? 74.213 46.406 -8.313 1.00 28.17 ? 1044 SER A CB 1 ATOM 8446 O OG . SER A 1 1044 ? 74.155 45.957 -9.662 1.00 29.91 ? 1044 SER A OG 1 ATOM 8447 N N . SER A 1 1045 ? 74.231 49.454 -9.817 1.00 32.84 ? 1045 SER A N 1 ATOM 8448 C CA . SER A 1 1045 ? 75.095 50.319 -10.646 1.00 35.11 ? 1045 SER A CA 1 ATOM 8449 C C . SER A 1 1045 ? 76.631 50.224 -10.489 1.00 36.04 ? 1045 SER A C 1 ATOM 8450 O O . SER A 1 1045 ? 77.371 51.216 -10.421 1.00 37.08 ? 1045 SER A O 1 ATOM 8451 C CB . SER A 1 1045 ? 74.585 51.765 -10.620 1.00 35.06 ? 1045 SER A CB 1 ATOM 8452 O OG . SER A 1 1045 ? 73.297 51.811 -11.202 1.00 35.87 ? 1045 SER A OG 1 ATOM 8453 O OXT . SER A 1 1045 ? 77.266 49.159 -10.455 1.00 37.29 ? 1045 SER A OXT 1 HETATM 8454 C C1 . NAG B 2 . ? 58.314 44.901 12.750 1.00 37.33 ? 1046 NAG A C1 1 HETATM 8455 C C2 . NAG B 2 . ? 59.376 44.548 13.785 1.00 34.25 ? 1046 NAG A C2 1 HETATM 8456 C C3 . NAG B 2 . ? 59.985 43.195 13.540 1.00 63.47 ? 1046 NAG A C3 1 HETATM 8457 C C4 . NAG B 2 . ? 58.973 42.161 13.819 1.00 81.24 ? 1046 NAG A C4 1 HETATM 8458 C C5 . NAG B 2 . ? 57.677 42.515 13.130 1.00 71.79 ? 1046 NAG A C5 1 HETATM 8459 C C6 . NAG B 2 . ? 56.505 41.901 13.921 1.00 73.80 ? 1046 NAG A C6 1 HETATM 8460 C C7 . NAG B 2 . ? 60.842 46.073 14.702 1.00 61.56 ? 1046 NAG A C7 1 HETATM 8461 C C8 . NAG B 2 . ? 60.035 45.739 15.984 1.00 91.28 ? 1046 NAG A C8 1 HETATM 8462 N N2 . NAG B 2 . ? 60.475 45.445 13.640 1.00 41.96 ? 1046 NAG A N2 1 HETATM 8463 O O3 . NAG B 2 . ? 61.106 43.021 14.398 1.00 61.96 ? 1046 NAG A O3 1 HETATM 8464 O O4 . NAG B 2 . ? 59.529 40.930 13.329 1.00 89.05 ? 1046 NAG A O4 1 HETATM 8465 O O5 . NAG B 2 . ? 57.324 43.967 13.014 1.00 53.40 ? 1046 NAG A O5 1 HETATM 8466 O O6 . NAG B 2 . ? 56.607 40.462 13.913 1.00 65.13 ? 1046 NAG A O6 1 HETATM 8467 O O7 . NAG B 2 . ? 61.723 46.909 14.691 1.00 89.67 ? 1046 NAG A O7 1 HETATM 8468 P P . PO4 C 3 . ? 45.239 65.706 -29.688 1.00 24.21 ? 1047 PO4 A P 1 HETATM 8469 O O1 . PO4 C 3 . ? 46.651 65.308 -30.071 1.00 28.88 ? 1047 PO4 A O1 1 HETATM 8470 O O2 . PO4 C 3 . ? 44.921 67.053 -30.314 1.00 29.51 ? 1047 PO4 A O2 1 HETATM 8471 O O3 . PO4 C 3 . ? 44.172 64.711 -30.165 1.00 29.12 ? 1047 PO4 A O3 1 HETATM 8472 O O4 . PO4 C 3 . ? 45.218 65.952 -28.200 1.00 30.25 ? 1047 PO4 A O4 1 HETATM 8473 ZN ZN . ZN D 4 . ? 34.861 64.375 8.030 1.00 8.16 ? 1048 ZN A ZN 1 HETATM 8474 C C1 . MRD E 5 . ? 16.820 62.603 10.386 1.00 22.85 ? 1049 MRD A C1 1 HETATM 8475 C C2 . MRD E 5 . ? 16.271 61.213 10.698 1.00 19.60 ? 1049 MRD A C2 1 HETATM 8476 O O2 . MRD E 5 . ? 14.878 61.181 10.302 1.00 21.60 ? 1049 MRD A O2 1 HETATM 8477 C CM . MRD E 5 . ? 16.999 60.167 9.859 1.00 21.38 ? 1049 MRD A CM 1 HETATM 8478 C C3 . MRD E 5 . ? 16.322 60.897 12.193 1.00 21.29 ? 1049 MRD A C3 1 HETATM 8479 C C4 . MRD E 5 . ? 17.723 60.674 12.750 1.00 25.35 ? 1049 MRD A C4 1 HETATM 8480 O O4 . MRD E 5 . ? 17.680 59.727 13.802 1.00 15.12 ? 1049 MRD A O4 1 HETATM 8481 C C5 . MRD E 5 . ? 18.315 61.995 13.240 1.00 22.01 ? 1049 MRD A C5 1 HETATM 8482 O O41 . WZ1 F 6 . ? 28.588 63.746 11.249 1.00 25.54 ? 1050 WZ1 A O41 1 HETATM 8483 C C41 . WZ1 F 6 . ? 28.201 65.038 11.779 1.00 25.58 ? 1050 WZ1 A C41 1 HETATM 8484 C C51 . WZ1 F 6 . ? 26.709 64.921 12.171 1.00 27.98 ? 1050 WZ1 A C51 1 HETATM 8485 C C61 . WZ1 F 6 . ? 26.410 63.916 13.308 1.00 31.72 ? 1050 WZ1 A C61 1 HETATM 8486 O O61 . WZ1 F 6 . ? 25.287 63.085 12.957 1.00 33.55 ? 1050 WZ1 A O61 1 HETATM 8487 O O01 . WZ1 F 6 . ? 26.226 66.238 12.570 1.00 29.47 ? 1050 WZ1 A O01 1 HETATM 8488 C C11 . WZ1 F 6 . ? 26.251 67.239 11.508 1.00 27.46 ? 1050 WZ1 A C11 1 HETATM 8489 O O11 . WZ1 F 6 . ? 25.599 66.786 10.318 1.00 29.36 ? 1050 WZ1 A O11 1 HETATM 8490 C C71 . WZ1 F 6 . ? 24.369 67.512 10.063 1.00 30.80 ? 1050 WZ1 A C71 1 HETATM 8491 C C21 . WZ1 F 6 . ? 27.690 67.492 11.036 1.00 24.61 ? 1050 WZ1 A C21 1 HETATM 8492 O O21 . WZ1 F 6 . ? 28.414 68.254 12.009 1.00 25.05 ? 1050 WZ1 A O21 1 HETATM 8493 C C31 . WZ1 F 6 . ? 28.438 66.174 10.729 1.00 21.01 ? 1050 WZ1 A C31 1 HETATM 8494 S S12 . WZ1 F 6 . ? 30.213 66.584 10.489 1.00 15.90 ? 1050 WZ1 A S12 1 HETATM 8495 C C12 . WZ1 F 6 . ? 30.744 65.286 9.344 1.00 11.96 ? 1050 WZ1 A C12 1 HETATM 8496 O O02 . WZ1 F 6 . ? 29.947 65.299 8.134 1.00 12.08 ? 1050 WZ1 A O02 1 HETATM 8497 C C52 . WZ1 F 6 . ? 30.093 66.490 7.326 1.00 12.22 ? 1050 WZ1 A C52 1 HETATM 8498 C C62 . WZ1 F 6 . ? 29.001 66.447 6.266 1.00 11.18 ? 1050 WZ1 A C62 1 HETATM 8499 O O62 . WZ1 F 6 . ? 27.724 66.620 6.955 1.00 12.82 ? 1050 WZ1 A O62 1 HETATM 8500 C C42 . WZ1 F 6 . ? 31.503 66.444 6.733 1.00 11.80 ? 1050 WZ1 A C42 1 HETATM 8501 O O42 . WZ1 F 6 . ? 31.700 67.609 5.923 1.00 9.17 ? 1050 WZ1 A O42 1 HETATM 8502 C C32 . WZ1 F 6 . ? 32.519 66.439 7.884 1.00 12.27 ? 1050 WZ1 A C32 1 HETATM 8503 O O32 . WZ1 F 6 . ? 33.795 66.069 7.305 1.00 10.77 ? 1050 WZ1 A O32 1 HETATM 8504 C C22 . WZ1 F 6 . ? 32.240 65.389 8.980 1.00 11.81 ? 1050 WZ1 A C22 1 HETATM 8505 O O22 . WZ1 F 6 . ? 32.719 64.086 8.573 1.00 10.80 ? 1050 WZ1 A O22 1 HETATM 8506 C C1 . MPD G 7 . ? 51.131 75.631 -13.635 1.00 36.64 ? 1051 MPD A C1 1 HETATM 8507 C C2 . MPD G 7 . ? 52.230 76.626 -13.303 1.00 37.60 ? 1051 MPD A C2 1 HETATM 8508 O O2 . MPD G 7 . ? 53.231 76.548 -14.358 1.00 38.11 ? 1051 MPD A O2 1 HETATM 8509 C CM . MPD G 7 . ? 51.584 78.008 -13.282 1.00 37.00 ? 1051 MPD A CM 1 HETATM 8510 C C3 . MPD G 7 . ? 52.871 76.237 -11.964 1.00 36.73 ? 1051 MPD A C3 1 HETATM 8511 C C4 . MPD G 7 . ? 53.734 77.246 -11.185 1.00 37.49 ? 1051 MPD A C4 1 HETATM 8512 O O4 . MPD G 7 . ? 54.828 76.558 -10.601 1.00 35.57 ? 1051 MPD A O4 1 HETATM 8513 C C5 . MPD G 7 . ? 54.288 78.418 -11.987 1.00 36.68 ? 1051 MPD A C5 1 HETATM 8514 C C1 . MPD H 7 . ? 35.062 71.228 15.515 1.00 48.94 ? 1052 MPD A C1 1 HETATM 8515 C C2 . MPD H 7 . ? 35.412 71.044 16.984 1.00 50.11 ? 1052 MPD A C2 1 HETATM 8516 O O2 . MPD H 7 . ? 36.805 70.635 17.019 1.00 49.42 ? 1052 MPD A O2 1 HETATM 8517 C CM . MPD H 7 . ? 35.264 72.363 17.745 1.00 49.96 ? 1052 MPD A CM 1 HETATM 8518 C C3 . MPD H 7 . ? 34.550 69.965 17.648 1.00 50.21 ? 1052 MPD A C3 1 HETATM 8519 C C4 . MPD H 7 . ? 33.272 69.612 16.890 1.00 51.06 ? 1052 MPD A C4 1 HETATM 8520 O O4 . MPD H 7 . ? 33.078 68.216 16.945 1.00 50.46 ? 1052 MPD A O4 1 HETATM 8521 C C5 . MPD H 7 . ? 32.062 70.349 17.465 1.00 51.49 ? 1052 MPD A C5 1 HETATM 8522 O O . HOH I 8 . ? 26.614 46.351 -37.314 1.00 44.67 ? 1053 HOH A O 1 HETATM 8523 O O . HOH I 8 . ? 22.912 48.930 -36.095 1.00 34.88 ? 1054 HOH A O 1 HETATM 8524 O O . HOH I 8 . ? 21.769 47.001 -34.580 1.00 49.72 ? 1055 HOH A O 1 HETATM 8525 O O . HOH I 8 . ? 20.807 51.126 -38.306 1.00 28.95 ? 1056 HOH A O 1 HETATM 8526 O O . HOH I 8 . ? 21.558 55.395 -36.313 1.00 27.32 ? 1057 HOH A O 1 HETATM 8527 O O . HOH I 8 . ? 23.876 55.867 -37.733 1.00 63.75 ? 1058 HOH A O 1 HETATM 8528 O O . HOH I 8 . ? 25.774 58.906 -38.735 1.00 54.22 ? 1059 HOH A O 1 HETATM 8529 O O . HOH I 8 . ? 24.889 59.425 -36.275 1.00 35.64 ? 1060 HOH A O 1 HETATM 8530 O O . HOH I 8 . ? 23.453 60.314 -39.227 1.00 52.22 ? 1061 HOH A O 1 HETATM 8531 O O . HOH I 8 . ? 21.957 61.465 -34.910 1.00 30.29 ? 1062 HOH A O 1 HETATM 8532 O O . HOH I 8 . ? 22.565 63.308 -33.098 1.00 20.55 ? 1063 HOH A O 1 HETATM 8533 O O . HOH I 8 . ? 20.803 59.018 -34.460 1.00 18.77 ? 1064 HOH A O 1 HETATM 8534 O O . HOH I 8 . ? 22.441 56.794 -34.109 1.00 16.63 ? 1065 HOH A O 1 HETATM 8535 O O . HOH I 8 . ? 19.520 51.891 -30.960 1.00 36.77 ? 1066 HOH A O 1 HETATM 8536 O O . HOH I 8 . ? 19.764 52.467 -27.108 1.00 27.99 ? 1067 HOH A O 1 HETATM 8537 O O . HOH I 8 . ? 20.150 52.687 -24.184 1.00 17.00 ? 1068 HOH A O 1 HETATM 8538 O O . HOH I 8 . ? 22.869 53.052 -24.336 1.00 12.58 ? 1069 HOH A O 1 HETATM 8539 O O . HOH I 8 . ? 24.722 51.092 -24.009 1.00 12.89 ? 1070 HOH A O 1 HETATM 8540 O O . HOH I 8 . ? 23.886 48.434 -24.147 1.00 27.39 ? 1071 HOH A O 1 HETATM 8541 O O . HOH I 8 . ? 22.948 48.681 -26.768 1.00 52.20 ? 1072 HOH A O 1 HETATM 8542 O O . HOH I 8 . ? 21.516 48.708 -22.418 1.00 38.24 ? 1073 HOH A O 1 HETATM 8543 O O . HOH I 8 . ? 19.133 50.340 -23.238 1.00 33.10 ? 1074 HOH A O 1 HETATM 8544 O O . HOH I 8 . ? 16.597 52.935 -22.375 1.00 26.59 ? 1075 HOH A O 1 HETATM 8545 O O . HOH I 8 . ? 16.076 52.817 -25.295 1.00 41.93 ? 1076 HOH A O 1 HETATM 8546 O O . HOH I 8 . ? 13.605 55.583 -22.321 1.00 37.90 ? 1077 HOH A O 1 HETATM 8547 O O A HOH I 8 . ? 13.453 58.088 -21.661 0.50 15.81 ? 1078 HOH A O 1 HETATM 8548 O O B HOH I 8 . ? 13.149 58.280 -23.082 0.50 21.34 ? 1078 HOH A O 1 HETATM 8549 O O . HOH I 8 . ? 13.907 60.781 -22.403 1.00 16.92 ? 1079 HOH A O 1 HETATM 8550 O O A HOH I 8 . ? 12.954 61.974 -25.036 0.50 21.45 ? 1080 HOH A O 1 HETATM 8551 O O B HOH I 8 . ? 12.148 61.362 -23.983 0.50 16.54 ? 1080 HOH A O 1 HETATM 8552 O O . HOH I 8 . ? 15.029 63.557 -25.867 1.00 24.19 ? 1081 HOH A O 1 HETATM 8553 O O . HOH I 8 . ? 18.517 64.922 -26.989 1.00 20.31 ? 1082 HOH A O 1 HETATM 8554 O O . HOH I 8 . ? 17.150 67.033 -25.980 1.00 28.91 ? 1083 HOH A O 1 HETATM 8555 O O . HOH I 8 . ? 17.232 70.096 -23.393 1.00 17.34 ? 1084 HOH A O 1 HETATM 8556 O O . HOH I 8 . ? 15.620 71.048 -27.010 1.00 55.66 ? 1085 HOH A O 1 HETATM 8557 O O . HOH I 8 . ? 18.625 70.430 -29.845 1.00 35.38 ? 1086 HOH A O 1 HETATM 8558 O O . HOH I 8 . ? 16.651 74.680 -28.498 1.00 48.18 ? 1087 HOH A O 1 HETATM 8559 O O . HOH I 8 . ? 16.943 77.738 -25.894 1.00 46.10 ? 1088 HOH A O 1 HETATM 8560 O O . HOH I 8 . ? 19.340 78.933 -25.473 1.00 31.74 ? 1089 HOH A O 1 HETATM 8561 O O . HOH I 8 . ? 20.903 78.395 -27.209 1.00 40.88 ? 1090 HOH A O 1 HETATM 8562 O O . HOH I 8 . ? 22.839 77.261 -27.474 1.00 27.62 ? 1091 HOH A O 1 HETATM 8563 O O . HOH I 8 . ? 23.243 78.392 -24.806 1.00 16.63 ? 1092 HOH A O 1 HETATM 8564 O O . HOH I 8 . ? 21.118 79.362 -23.556 1.00 21.26 ? 1093 HOH A O 1 HETATM 8565 O O . HOH I 8 . ? 19.159 83.453 -25.818 1.00 31.65 ? 1094 HOH A O 1 HETATM 8566 O O . HOH I 8 . ? 21.502 86.063 -30.807 1.00 32.85 ? 1095 HOH A O 1 HETATM 8567 O O . HOH I 8 . ? 23.278 86.987 -32.616 1.00 33.08 ? 1096 HOH A O 1 HETATM 8568 O O . HOH I 8 . ? 25.621 86.088 -31.877 1.00 17.35 ? 1097 HOH A O 1 HETATM 8569 O O . HOH I 8 . ? 27.195 89.784 -31.841 1.00 37.34 ? 1098 HOH A O 1 HETATM 8570 O O . HOH I 8 . ? 25.878 91.625 -32.835 1.00 39.46 ? 1099 HOH A O 1 HETATM 8571 O O . HOH I 8 . ? 28.058 93.556 -29.790 1.00 35.79 ? 1100 HOH A O 1 HETATM 8572 O O . HOH I 8 . ? 26.815 91.721 -27.655 1.00 30.10 ? 1101 HOH A O 1 HETATM 8573 O O . HOH I 8 . ? 28.109 90.892 -25.377 1.00 21.27 ? 1102 HOH A O 1 HETATM 8574 O O . HOH I 8 . ? 29.579 88.716 -26.256 1.00 13.13 ? 1103 HOH A O 1 HETATM 8575 O O . HOH I 8 . ? 27.031 87.894 -23.649 1.00 25.98 ? 1104 HOH A O 1 HETATM 8576 O O . HOH I 8 . ? 25.127 88.769 -25.231 1.00 30.78 ? 1105 HOH A O 1 HETATM 8577 O O . HOH I 8 . ? 23.908 90.893 -26.150 1.00 39.93 ? 1106 HOH A O 1 HETATM 8578 O O . HOH I 8 . ? 22.535 88.241 -22.731 1.00 48.26 ? 1107 HOH A O 1 HETATM 8579 O O . HOH I 8 . ? 22.767 88.596 -18.707 1.00 38.48 ? 1108 HOH A O 1 HETATM 8580 O O . HOH I 8 . ? 23.271 87.195 -16.460 1.00 38.92 ? 1109 HOH A O 1 HETATM 8581 O O . HOH I 8 . ? 22.822 84.890 -17.041 1.00 32.13 ? 1110 HOH A O 1 HETATM 8582 O O . HOH I 8 . ? 24.923 83.082 -16.914 1.00 21.34 ? 1111 HOH A O 1 HETATM 8583 O O . HOH I 8 . ? 25.702 87.586 -16.177 1.00 46.13 ? 1112 HOH A O 1 HETATM 8584 O O . HOH I 8 . ? 27.671 86.287 -14.505 1.00 29.91 ? 1113 HOH A O 1 HETATM 8585 O O . HOH I 8 . ? 30.325 87.195 -15.072 1.00 24.24 ? 1114 HOH A O 1 HETATM 8586 O O . HOH I 8 . ? 29.756 87.334 -17.967 1.00 27.62 ? 1115 HOH A O 1 HETATM 8587 O O . HOH I 8 . ? 27.563 89.012 -18.238 1.00 45.03 ? 1116 HOH A O 1 HETATM 8588 O O . HOH I 8 . ? 26.517 88.878 -21.314 1.00 55.00 ? 1117 HOH A O 1 HETATM 8589 O O . HOH I 8 . ? 21.638 86.127 -19.258 1.00 29.77 ? 1118 HOH A O 1 HETATM 8590 O O . HOH I 8 . ? 19.744 84.271 -18.419 1.00 30.13 ? 1119 HOH A O 1 HETATM 8591 O O . HOH I 8 . ? 17.406 81.209 -17.257 1.00 45.29 ? 1120 HOH A O 1 HETATM 8592 O O . HOH I 8 . ? 15.012 84.081 -18.851 1.00 52.30 ? 1121 HOH A O 1 HETATM 8593 O O . HOH I 8 . ? 14.094 88.313 -19.939 1.00 30.49 ? 1122 HOH A O 1 HETATM 8594 O O . HOH I 8 . ? 12.531 77.603 -18.947 1.00 50.23 ? 1123 HOH A O 1 HETATM 8595 O O . HOH I 8 . ? 12.921 74.808 -18.917 1.00 39.74 ? 1124 HOH A O 1 HETATM 8596 O O . HOH I 8 . ? 14.961 73.649 -21.905 1.00 36.36 ? 1125 HOH A O 1 HETATM 8597 O O . HOH I 8 . ? 12.690 74.345 -22.994 1.00 41.72 ? 1126 HOH A O 1 HETATM 8598 O O . HOH I 8 . ? 16.263 74.801 -23.960 1.00 41.78 ? 1127 HOH A O 1 HETATM 8599 O O . HOH I 8 . ? 16.070 71.954 -18.981 1.00 20.12 ? 1128 HOH A O 1 HETATM 8600 O O . HOH I 8 . ? 17.123 70.289 -16.242 1.00 12.39 ? 1129 HOH A O 1 HETATM 8601 O O . HOH I 8 . ? 16.467 67.826 -19.769 1.00 20.27 ? 1130 HOH A O 1 HETATM 8602 O O . HOH I 8 . ? 20.574 66.176 -19.568 1.00 12.99 ? 1131 HOH A O 1 HETATM 8603 O O . HOH I 8 . ? 14.688 66.353 -15.399 1.00 21.74 ? 1132 HOH A O 1 HETATM 8604 O O . HOH I 8 . ? 14.416 63.935 -16.284 1.00 18.74 ? 1133 HOH A O 1 HETATM 8605 O O . HOH I 8 . ? 14.613 61.930 -14.410 1.00 23.13 ? 1134 HOH A O 1 HETATM 8606 O O . HOH I 8 . ? 14.241 62.852 -12.045 1.00 20.42 ? 1135 HOH A O 1 HETATM 8607 O O . HOH I 8 . ? 12.394 64.378 -12.384 1.00 31.46 ? 1136 HOH A O 1 HETATM 8608 O O . HOH I 8 . ? 10.663 62.458 -12.211 1.00 36.90 ? 1137 HOH A O 1 HETATM 8609 O O . HOH I 8 . ? 10.008 62.912 -14.663 1.00 38.28 ? 1138 HOH A O 1 HETATM 8610 O O . HOH I 8 . ? 8.806 60.446 -16.574 1.00 54.46 ? 1139 HOH A O 1 HETATM 8611 O O . HOH I 8 . ? 11.407 61.356 -18.167 1.00 21.57 ? 1140 HOH A O 1 HETATM 8612 O O . HOH I 8 . ? 13.377 62.362 -19.944 1.00 19.23 ? 1141 HOH A O 1 HETATM 8613 O O . HOH I 8 . ? 11.402 56.673 -18.396 1.00 39.63 ? 1142 HOH A O 1 HETATM 8614 O O . HOH I 8 . ? 9.837 55.458 -16.221 1.00 47.61 ? 1143 HOH A O 1 HETATM 8615 O O . HOH I 8 . ? 12.257 55.701 -14.997 1.00 18.82 ? 1144 HOH A O 1 HETATM 8616 O O . HOH I 8 . ? 14.373 54.263 -16.147 1.00 19.05 ? 1145 HOH A O 1 HETATM 8617 O O . HOH I 8 . ? 13.375 51.945 -15.140 1.00 27.25 ? 1146 HOH A O 1 HETATM 8618 O O . HOH I 8 . ? 12.703 51.745 -11.897 1.00 28.56 ? 1147 HOH A O 1 HETATM 8619 O O . HOH I 8 . ? 11.153 48.841 -11.755 1.00 48.27 ? 1148 HOH A O 1 HETATM 8620 O O . HOH I 8 . ? 10.473 50.693 -9.100 1.00 30.61 ? 1149 HOH A O 1 HETATM 8621 O O . HOH I 8 . ? 9.476 48.084 -8.318 1.00 41.47 ? 1150 HOH A O 1 HETATM 8622 O O . HOH I 8 . ? 8.492 45.536 -7.481 1.00 54.94 ? 1151 HOH A O 1 HETATM 8623 O O . HOH I 8 . ? 10.325 47.301 -4.747 1.00 45.09 ? 1152 HOH A O 1 HETATM 8624 O O . HOH I 8 . ? 11.873 48.289 -2.333 1.00 31.27 ? 1153 HOH A O 1 HETATM 8625 O O . HOH I 8 . ? 13.453 50.937 -1.463 1.00 22.83 ? 1154 HOH A O 1 HETATM 8626 O O . HOH I 8 . ? 14.401 50.750 1.078 1.00 25.65 ? 1155 HOH A O 1 HETATM 8627 O O . HOH I 8 . ? 13.478 48.365 1.728 1.00 29.81 ? 1156 HOH A O 1 HETATM 8628 O O . HOH I 8 . ? 10.411 51.759 2.522 1.00 31.76 ? 1157 HOH A O 1 HETATM 8629 O O . HOH I 8 . ? 10.885 53.665 4.242 1.00 26.81 ? 1158 HOH A O 1 HETATM 8630 O O . HOH I 8 . ? 11.406 53.274 6.969 1.00 18.30 ? 1159 HOH A O 1 HETATM 8631 O O . HOH I 8 . ? 13.791 54.254 4.550 1.00 16.24 ? 1160 HOH A O 1 HETATM 8632 O O . HOH I 8 . ? 12.496 56.418 5.442 1.00 17.91 ? 1161 HOH A O 1 HETATM 8633 O O . HOH I 8 . ? 11.618 58.864 8.063 1.00 24.71 ? 1162 HOH A O 1 HETATM 8634 O O . HOH I 8 . ? 9.789 59.948 6.593 1.00 31.14 ? 1163 HOH A O 1 HETATM 8635 O O . HOH I 8 . ? 11.326 62.347 5.377 1.00 33.69 ? 1164 HOH A O 1 HETATM 8636 O O . HOH I 8 . ? 13.233 63.174 6.680 1.00 34.48 ? 1165 HOH A O 1 HETATM 8637 O O . HOH I 8 . ? 13.769 60.869 7.851 1.00 25.60 ? 1166 HOH A O 1 HETATM 8638 O O . HOH I 8 . ? 14.475 60.154 5.253 1.00 13.70 ? 1167 HOH A O 1 HETATM 8639 O O . HOH I 8 . ? 14.472 65.613 5.619 1.00 33.41 ? 1168 HOH A O 1 HETATM 8640 O O . HOH I 8 . ? 13.510 67.876 4.550 1.00 38.54 ? 1169 HOH A O 1 HETATM 8641 O O . HOH I 8 . ? 11.617 66.876 2.962 1.00 47.03 ? 1170 HOH A O 1 HETATM 8642 O O . HOH I 8 . ? 13.256 68.713 0.936 1.00 19.91 ? 1171 HOH A O 1 HETATM 8643 O O . HOH I 8 . ? 12.590 71.017 -0.283 1.00 24.22 ? 1172 HOH A O 1 HETATM 8644 O O . HOH I 8 . ? 10.801 68.018 -1.833 1.00 39.22 ? 1173 HOH A O 1 HETATM 8645 O O . HOH I 8 . ? 13.184 66.765 -4.818 1.00 15.72 ? 1174 HOH A O 1 HETATM 8646 O O . HOH I 8 . ? 10.930 65.506 -5.426 1.00 37.11 ? 1175 HOH A O 1 HETATM 8647 O O . HOH I 8 . ? 11.269 62.598 -4.450 1.00 39.19 ? 1176 HOH A O 1 HETATM 8648 O O . HOH I 8 . ? 12.989 62.019 -2.346 1.00 23.99 ? 1177 HOH A O 1 HETATM 8649 O O . HOH I 8 . ? 11.548 61.624 -0.169 1.00 41.22 ? 1178 HOH A O 1 HETATM 8650 O O . HOH I 8 . ? 10.396 62.346 2.020 1.00 29.89 ? 1179 HOH A O 1 HETATM 8651 O O . HOH I 8 . ? 9.954 64.626 4.623 1.00 38.61 ? 1180 HOH A O 1 HETATM 8652 O O . HOH I 8 . ? 6.616 59.532 2.733 1.00 44.15 ? 1181 HOH A O 1 HETATM 8653 O O . HOH I 8 . ? 7.484 58.053 0.471 1.00 34.30 ? 1182 HOH A O 1 HETATM 8654 O O . HOH I 8 . ? 10.097 57.983 -3.162 1.00 30.92 ? 1183 HOH A O 1 HETATM 8655 O O . HOH I 8 . ? 11.855 59.495 -4.853 1.00 20.23 ? 1184 HOH A O 1 HETATM 8656 O O . HOH I 8 . ? 14.149 59.697 -3.378 1.00 14.69 ? 1185 HOH A O 1 HETATM 8657 O O . HOH I 8 . ? 14.001 57.894 -1.261 1.00 19.94 ? 1186 HOH A O 1 HETATM 8658 O O . HOH I 8 . ? 13.481 53.619 1.935 1.00 16.86 ? 1187 HOH A O 1 HETATM 8659 O O . HOH I 8 . ? 17.591 52.851 6.418 1.00 10.95 ? 1188 HOH A O 1 HETATM 8660 O O . HOH I 8 . ? 19.337 53.645 8.236 1.00 11.86 ? 1189 HOH A O 1 HETATM 8661 O O . HOH I 8 . ? 20.150 56.132 7.197 1.00 11.59 ? 1190 HOH A O 1 HETATM 8662 O O . HOH I 8 . ? 21.757 57.254 5.127 1.00 11.56 ? 1191 HOH A O 1 HETATM 8663 O O . HOH I 8 . ? 23.871 58.307 6.373 1.00 13.51 ? 1192 HOH A O 1 HETATM 8664 O O . HOH I 8 . ? 27.089 59.462 8.458 1.00 21.53 ? 1193 HOH A O 1 HETATM 8665 O O . HOH I 8 . ? 27.342 61.201 10.351 1.00 22.93 ? 1194 HOH A O 1 HETATM 8666 O O . HOH I 8 . ? 24.796 61.452 9.192 1.00 17.84 ? 1195 HOH A O 1 HETATM 8667 O O . HOH I 8 . ? 24.357 63.260 7.334 1.00 21.83 ? 1196 HOH A O 1 HETATM 8668 O O . HOH I 8 . ? 26.044 65.078 8.139 1.00 23.11 ? 1197 HOH A O 1 HETATM 8669 O O . HOH I 8 . ? 20.966 65.341 7.699 1.00 15.15 ? 1198 HOH A O 1 HETATM 8670 O O . HOH I 8 . ? 20.910 68.000 8.610 1.00 16.01 ? 1199 HOH A O 1 HETATM 8671 O O . HOH I 8 . ? 21.041 67.760 11.603 1.00 32.76 ? 1200 HOH A O 1 HETATM 8672 O O . HOH I 8 . ? 21.083 65.301 12.100 1.00 27.85 ? 1201 HOH A O 1 HETATM 8673 O O . HOH I 8 . ? 21.105 63.456 14.530 1.00 51.62 ? 1202 HOH A O 1 HETATM 8674 O O . HOH I 8 . ? 22.713 62.707 16.211 1.00 20.88 ? 1203 HOH A O 1 HETATM 8675 O O . HOH I 8 . ? 23.178 64.479 18.307 1.00 34.35 ? 1204 HOH A O 1 HETATM 8676 O O . HOH I 8 . ? 25.526 66.154 17.320 1.00 26.20 ? 1205 HOH A O 1 HETATM 8677 O O . HOH I 8 . ? 26.425 63.769 17.140 1.00 16.43 ? 1206 HOH A O 1 HETATM 8678 O O . HOH I 8 . ? 28.695 65.306 19.759 1.00 15.71 ? 1207 HOH A O 1 HETATM 8679 O O . HOH I 8 . ? 29.985 67.079 17.989 1.00 25.57 ? 1208 HOH A O 1 HETATM 8680 O O . HOH I 8 . ? 32.018 65.681 19.073 1.00 15.02 ? 1209 HOH A O 1 HETATM 8681 O O . HOH I 8 . ? 33.184 67.095 21.360 1.00 21.32 ? 1210 HOH A O 1 HETATM 8682 O O . HOH I 8 . ? 32.684 69.705 22.086 1.00 29.99 ? 1211 HOH A O 1 HETATM 8683 O O . HOH I 8 . ? 32.761 69.450 24.666 1.00 24.90 ? 1212 HOH A O 1 HETATM 8684 O O . HOH I 8 . ? 35.920 68.424 23.442 1.00 29.06 ? 1213 HOH A O 1 HETATM 8685 O O . HOH I 8 . ? 35.786 68.057 20.481 1.00 28.59 ? 1214 HOH A O 1 HETATM 8686 O O . HOH I 8 . ? 36.489 70.232 19.833 1.00 42.67 ? 1215 HOH A O 1 HETATM 8687 O O . HOH I 8 . ? 38.391 73.783 18.086 1.00 29.67 ? 1216 HOH A O 1 HETATM 8688 O O . HOH I 8 . ? 39.508 74.724 20.728 1.00 54.42 ? 1217 HOH A O 1 HETATM 8689 O O . HOH I 8 . ? 41.928 73.511 22.947 1.00 40.09 ? 1218 HOH A O 1 HETATM 8690 O O . HOH I 8 . ? 43.646 71.700 26.089 1.00 49.60 ? 1219 HOH A O 1 HETATM 8691 O O . HOH I 8 . ? 42.454 68.835 26.399 1.00 40.30 ? 1220 HOH A O 1 HETATM 8692 O O . HOH I 8 . ? 44.673 67.896 28.173 1.00 38.38 ? 1221 HOH A O 1 HETATM 8693 O O . HOH I 8 . ? 46.553 68.639 26.511 1.00 29.01 ? 1222 HOH A O 1 HETATM 8694 O O . HOH I 8 . ? 48.636 68.289 24.940 1.00 49.21 ? 1223 HOH A O 1 HETATM 8695 O O . HOH I 8 . ? 50.767 69.682 24.052 1.00 60.05 ? 1224 HOH A O 1 HETATM 8696 O O . HOH I 8 . ? 52.246 67.895 22.563 1.00 57.51 ? 1225 HOH A O 1 HETATM 8697 O O . HOH I 8 . ? 53.377 66.349 20.492 1.00 50.36 ? 1226 HOH A O 1 HETATM 8698 O O . HOH I 8 . ? 53.024 69.749 18.261 1.00 24.77 ? 1227 HOH A O 1 HETATM 8699 O O . HOH I 8 . ? 52.547 72.610 18.222 1.00 28.18 ? 1228 HOH A O 1 HETATM 8700 O O . HOH I 8 . ? 54.377 72.961 16.318 1.00 35.01 ? 1229 HOH A O 1 HETATM 8701 O O . HOH I 8 . ? 54.478 74.219 12.170 1.00 51.02 ? 1230 HOH A O 1 HETATM 8702 O O . HOH I 8 . ? 54.286 72.060 10.770 1.00 54.86 ? 1231 HOH A O 1 HETATM 8703 O O . HOH I 8 . ? 52.686 70.797 8.824 1.00 31.71 ? 1232 HOH A O 1 HETATM 8704 O O . HOH I 8 . ? 50.447 72.298 9.168 1.00 18.82 ? 1233 HOH A O 1 HETATM 8705 O O . HOH I 8 . ? 51.670 74.676 8.429 1.00 37.45 ? 1234 HOH A O 1 HETATM 8706 O O . HOH I 8 . ? 48.437 76.662 8.225 1.00 30.56 ? 1235 HOH A O 1 HETATM 8707 O O . HOH I 8 . ? 46.785 74.522 7.765 1.00 11.83 ? 1236 HOH A O 1 HETATM 8708 O O . HOH I 8 . ? 46.126 77.820 9.497 1.00 21.12 ? 1237 HOH A O 1 HETATM 8709 O O . HOH I 8 . ? 47.423 78.405 11.640 1.00 28.72 ? 1238 HOH A O 1 HETATM 8710 O O . HOH I 8 . ? 47.189 77.441 14.217 1.00 36.83 ? 1239 HOH A O 1 HETATM 8711 O O . HOH I 8 . ? 45.379 78.125 15.925 1.00 47.94 ? 1240 HOH A O 1 HETATM 8712 O O . HOH I 8 . ? 45.130 80.567 14.858 1.00 51.36 ? 1241 HOH A O 1 HETATM 8713 O O . HOH I 8 . ? 40.658 81.380 11.573 1.00 39.81 ? 1242 HOH A O 1 HETATM 8714 O O . HOH I 8 . ? 38.517 80.194 12.489 1.00 52.21 ? 1243 HOH A O 1 HETATM 8715 O O . HOH I 8 . ? 38.639 82.415 10.108 1.00 38.46 ? 1244 HOH A O 1 HETATM 8716 O O . HOH I 8 . ? 41.202 83.154 8.398 1.00 44.02 ? 1245 HOH A O 1 HETATM 8717 O O . HOH I 8 . ? 43.480 80.800 5.049 1.00 23.23 ? 1246 HOH A O 1 HETATM 8718 O O . HOH I 8 . ? 46.090 79.592 4.913 1.00 25.47 ? 1247 HOH A O 1 HETATM 8719 O O . HOH I 8 . ? 49.290 76.528 5.429 1.00 29.71 ? 1248 HOH A O 1 HETATM 8720 O O . HOH I 8 . ? 50.900 77.244 2.034 1.00 31.53 ? 1249 HOH A O 1 HETATM 8721 O O . HOH I 8 . ? 52.604 75.269 1.897 1.00 38.33 ? 1250 HOH A O 1 HETATM 8722 O O . HOH I 8 . ? 55.174 75.762 2.199 1.00 43.82 ? 1251 HOH A O 1 HETATM 8723 O O . HOH I 8 . ? 56.923 76.100 0.010 1.00 34.22 ? 1252 HOH A O 1 HETATM 8724 O O . HOH I 8 . ? 57.198 75.411 -2.848 1.00 28.15 ? 1253 HOH A O 1 HETATM 8725 O O . HOH I 8 . ? 59.248 77.109 -4.241 1.00 29.26 ? 1254 HOH A O 1 HETATM 8726 O O . HOH I 8 . ? 61.604 77.059 -5.120 1.00 52.60 ? 1255 HOH A O 1 HETATM 8727 O O . HOH I 8 . ? 60.451 74.918 -4.678 1.00 36.02 ? 1256 HOH A O 1 HETATM 8728 O O . HOH I 8 . ? 60.823 73.842 -0.265 1.00 52.10 ? 1257 HOH A O 1 HETATM 8729 O O . HOH I 8 . ? 60.590 72.690 2.030 1.00 42.83 ? 1258 HOH A O 1 HETATM 8730 O O . HOH I 8 . ? 59.776 71.308 0.152 1.00 34.96 ? 1259 HOH A O 1 HETATM 8731 O O . HOH I 8 . ? 59.168 70.712 2.988 1.00 47.31 ? 1260 HOH A O 1 HETATM 8732 O O . HOH I 8 . ? 59.367 68.221 2.471 1.00 22.28 ? 1261 HOH A O 1 HETATM 8733 O O . HOH I 8 . ? 56.603 66.877 5.222 1.00 30.07 ? 1262 HOH A O 1 HETATM 8734 O O . HOH I 8 . ? 55.199 68.528 3.581 1.00 33.74 ? 1263 HOH A O 1 HETATM 8735 O O . HOH I 8 . ? 53.592 69.415 2.240 1.00 38.13 ? 1264 HOH A O 1 HETATM 8736 O O . HOH I 8 . ? 51.858 69.048 3.856 1.00 31.99 ? 1265 HOH A O 1 HETATM 8737 O O . HOH I 8 . ? 49.899 67.499 4.238 1.00 17.67 ? 1266 HOH A O 1 HETATM 8738 O O . HOH I 8 . ? 49.334 68.310 6.733 1.00 26.93 ? 1267 HOH A O 1 HETATM 8739 O O . HOH I 8 . ? 51.311 66.485 8.486 1.00 24.15 ? 1268 HOH A O 1 HETATM 8740 O O . HOH I 8 . ? 53.170 68.114 9.137 1.00 30.16 ? 1269 HOH A O 1 HETATM 8741 O O . HOH I 8 . ? 53.505 66.612 7.082 1.00 41.58 ? 1270 HOH A O 1 HETATM 8742 O O . HOH I 8 . ? 55.612 67.224 10.233 1.00 43.15 ? 1271 HOH A O 1 HETATM 8743 O O . HOH I 8 . ? 55.575 67.518 13.367 1.00 31.09 ? 1272 HOH A O 1 HETATM 8744 O O . HOH I 8 . ? 57.410 69.162 13.651 1.00 32.80 ? 1273 HOH A O 1 HETATM 8745 O O . HOH I 8 . ? 59.825 68.849 16.661 1.00 53.96 ? 1274 HOH A O 1 HETATM 8746 O O . HOH I 8 . ? 57.932 69.489 19.978 1.00 40.34 ? 1275 HOH A O 1 HETATM 8747 O O . HOH I 8 . ? 57.202 67.627 22.704 1.00 44.20 ? 1276 HOH A O 1 HETATM 8748 O O . HOH I 8 . ? 57.044 64.813 24.090 1.00 30.12 ? 1277 HOH A O 1 HETATM 8749 O O . HOH I 8 . ? 59.351 62.479 25.718 1.00 35.52 ? 1278 HOH A O 1 HETATM 8750 O O . HOH I 8 . ? 62.500 62.174 25.482 1.00 33.57 ? 1279 HOH A O 1 HETATM 8751 O O . HOH I 8 . ? 63.640 57.691 25.482 1.00 44.70 ? 1280 HOH A O 1 HETATM 8752 O O . HOH I 8 . ? 62.560 55.980 27.277 1.00 48.58 ? 1281 HOH A O 1 HETATM 8753 O O . HOH I 8 . ? 59.332 55.653 27.062 1.00 32.33 ? 1282 HOH A O 1 HETATM 8754 O O . HOH I 8 . ? 58.125 52.936 26.295 1.00 45.53 ? 1283 HOH A O 1 HETATM 8755 O O . HOH I 8 . ? 55.874 52.034 27.246 1.00 33.14 ? 1284 HOH A O 1 HETATM 8756 O O . HOH I 8 . ? 56.259 49.326 27.127 1.00 43.91 ? 1285 HOH A O 1 HETATM 8757 O O . HOH I 8 . ? 58.282 48.749 25.621 1.00 48.88 ? 1286 HOH A O 1 HETATM 8758 O O . HOH I 8 . ? 59.629 50.956 24.802 1.00 35.26 ? 1287 HOH A O 1 HETATM 8759 O O . HOH I 8 . ? 58.721 51.249 22.213 1.00 25.65 ? 1288 HOH A O 1 HETATM 8760 O O . HOH I 8 . ? 57.515 49.103 21.365 1.00 25.87 ? 1289 HOH A O 1 HETATM 8761 O O . HOH I 8 . ? 56.899 47.675 23.257 1.00 44.82 ? 1290 HOH A O 1 HETATM 8762 O O . HOH I 8 . ? 54.033 46.890 23.441 1.00 33.94 ? 1291 HOH A O 1 HETATM 8763 O O A HOH I 8 . ? 51.978 50.442 27.371 0.50 18.09 ? 1292 HOH A O 1 HETATM 8764 O O B HOH I 8 . ? 52.391 49.026 25.505 0.50 21.15 ? 1292 HOH A O 1 HETATM 8765 O O . HOH I 8 . ? 49.233 49.955 28.302 1.00 17.95 ? 1293 HOH A O 1 HETATM 8766 O O . HOH I 8 . ? 50.036 47.407 29.035 1.00 26.52 ? 1294 HOH A O 1 HETATM 8767 O O . HOH I 8 . ? 47.262 45.921 26.690 1.00 30.77 ? 1295 HOH A O 1 HETATM 8768 O O . HOH I 8 . ? 46.346 43.773 28.360 1.00 38.29 ? 1296 HOH A O 1 HETATM 8769 O O . HOH I 8 . ? 47.551 43.787 30.664 1.00 45.55 ? 1297 HOH A O 1 HETATM 8770 O O . HOH I 8 . ? 44.745 45.130 32.546 1.00 38.25 ? 1298 HOH A O 1 HETATM 8771 O O . HOH I 8 . ? 42.691 46.378 32.885 1.00 42.57 ? 1299 HOH A O 1 HETATM 8772 O O . HOH I 8 . ? 42.211 48.810 31.308 1.00 22.49 ? 1300 HOH A O 1 HETATM 8773 O O . HOH I 8 . ? 41.323 50.507 33.120 1.00 22.05 ? 1301 HOH A O 1 HETATM 8774 O O . HOH I 8 . ? 39.387 49.322 30.179 1.00 20.72 ? 1302 HOH A O 1 HETATM 8775 O O . HOH I 8 . ? 37.528 47.320 29.725 1.00 18.84 ? 1303 HOH A O 1 HETATM 8776 O O . HOH I 8 . ? 37.149 45.679 27.478 1.00 13.19 ? 1304 HOH A O 1 HETATM 8777 O O . HOH I 8 . ? 39.266 43.610 26.866 1.00 29.14 ? 1305 HOH A O 1 HETATM 8778 O O . HOH I 8 . ? 39.812 45.460 25.581 1.00 28.59 ? 1306 HOH A O 1 HETATM 8779 O O . HOH I 8 . ? 39.038 43.124 22.692 1.00 27.04 ? 1307 HOH A O 1 HETATM 8780 O O . HOH I 8 . ? 39.674 39.704 20.127 1.00 27.34 ? 1308 HOH A O 1 HETATM 8781 O O . HOH I 8 . ? 38.097 38.671 21.958 1.00 34.70 ? 1309 HOH A O 1 HETATM 8782 O O . HOH I 8 . ? 34.940 38.226 22.238 1.00 44.34 ? 1310 HOH A O 1 HETATM 8783 O O . HOH I 8 . ? 34.595 35.816 23.720 1.00 49.19 ? 1311 HOH A O 1 HETATM 8784 O O . HOH I 8 . ? 32.504 34.221 25.411 1.00 47.32 ? 1312 HOH A O 1 HETATM 8785 O O . HOH I 8 . ? 30.033 30.336 24.462 1.00 44.98 ? 1313 HOH A O 1 HETATM 8786 O O . HOH I 8 . ? 29.560 31.729 21.931 1.00 29.19 ? 1314 HOH A O 1 HETATM 8787 O O . HOH I 8 . ? 31.796 33.707 17.018 1.00 31.71 ? 1315 HOH A O 1 HETATM 8788 O O . HOH I 8 . ? 34.308 34.464 16.269 1.00 20.77 ? 1316 HOH A O 1 HETATM 8789 O O . HOH I 8 . ? 33.380 35.386 18.485 1.00 65.33 ? 1317 HOH A O 1 HETATM 8790 O O . HOH I 8 . ? 36.476 33.152 17.269 1.00 41.57 ? 1318 HOH A O 1 HETATM 8791 O O . HOH I 8 . ? 32.590 31.000 15.920 1.00 49.73 ? 1319 HOH A O 1 HETATM 8792 O O . HOH I 8 . ? 36.854 29.251 13.155 1.00 32.21 ? 1320 HOH A O 1 HETATM 8793 O O . HOH I 8 . ? 39.996 35.392 11.373 1.00 23.98 ? 1321 HOH A O 1 HETATM 8794 O O . HOH I 8 . ? 40.172 39.336 9.184 1.00 28.13 ? 1322 HOH A O 1 HETATM 8795 O O A HOH I 8 . ? 44.270 41.008 7.820 0.50 19.99 ? 1323 HOH A O 1 HETATM 8796 O O B HOH I 8 . ? 42.743 39.804 7.834 0.50 25.92 ? 1323 HOH A O 1 HETATM 8797 O O . HOH I 8 . ? 41.700 43.256 7.938 1.00 15.69 ? 1324 HOH A O 1 HETATM 8798 O O . HOH I 8 . ? 44.461 46.082 10.065 1.00 12.94 ? 1325 HOH A O 1 HETATM 8799 O O . HOH I 8 . ? 45.278 44.389 12.009 1.00 40.57 ? 1326 HOH A O 1 HETATM 8800 O O . HOH I 8 . ? 46.858 46.017 11.463 1.00 31.56 ? 1327 HOH A O 1 HETATM 8801 O O . HOH I 8 . ? 48.567 44.904 10.093 1.00 37.58 ? 1328 HOH A O 1 HETATM 8802 O O . HOH I 8 . ? 46.606 43.059 9.841 1.00 33.81 ? 1329 HOH A O 1 HETATM 8803 O O . HOH I 8 . ? 49.066 41.898 8.371 1.00 25.11 ? 1330 HOH A O 1 HETATM 8804 O O . HOH I 8 . ? 50.050 44.126 7.072 1.00 16.20 ? 1331 HOH A O 1 HETATM 8805 O O . HOH I 8 . ? 49.449 44.250 4.444 1.00 15.51 ? 1332 HOH A O 1 HETATM 8806 O O . HOH I 8 . ? 51.745 44.430 3.027 1.00 22.60 ? 1333 HOH A O 1 HETATM 8807 O O . HOH I 8 . ? 51.907 46.552 1.303 1.00 12.32 ? 1334 HOH A O 1 HETATM 8808 O O . HOH I 8 . ? 49.917 48.483 1.425 1.00 10.17 ? 1335 HOH A O 1 HETATM 8809 O O . HOH I 8 . ? 47.553 46.045 3.693 1.00 11.34 ? 1336 HOH A O 1 HETATM 8810 O O . HOH I 8 . ? 48.207 41.723 3.703 1.00 18.37 ? 1337 HOH A O 1 HETATM 8811 O O . HOH I 8 . ? 47.761 39.855 1.805 1.00 48.87 ? 1338 HOH A O 1 HETATM 8812 O O . HOH I 8 . ? 49.738 41.112 1.386 1.00 35.24 ? 1339 HOH A O 1 HETATM 8813 O O . HOH I 8 . ? 48.544 40.910 -0.995 1.00 24.43 ? 1340 HOH A O 1 HETATM 8814 O O . HOH I 8 . ? 47.542 42.989 -2.342 1.00 16.14 ? 1341 HOH A O 1 HETATM 8815 O O . HOH I 8 . ? 48.040 41.724 -5.275 1.00 25.54 ? 1342 HOH A O 1 HETATM 8816 O O . HOH I 8 . ? 45.497 41.579 -5.895 1.00 33.05 ? 1343 HOH A O 1 HETATM 8817 O O . HOH I 8 . ? 43.528 41.874 -7.592 1.00 27.81 ? 1344 HOH A O 1 HETATM 8818 O O . HOH I 8 . ? 45.654 42.195 -9.037 1.00 33.66 ? 1345 HOH A O 1 HETATM 8819 O O . HOH I 8 . ? 47.987 43.967 -8.658 1.00 18.19 ? 1346 HOH A O 1 HETATM 8820 O O . HOH I 8 . ? 48.800 44.249 -6.196 1.00 13.78 ? 1347 HOH A O 1 HETATM 8821 O O . HOH I 8 . ? 51.069 44.305 -8.004 1.00 10.85 ? 1348 HOH A O 1 HETATM 8822 O O . HOH I 8 . ? 49.235 41.847 -10.568 1.00 33.38 ? 1349 HOH A O 1 HETATM 8823 O O . HOH I 8 . ? 47.314 42.027 -12.277 1.00 43.46 ? 1350 HOH A O 1 HETATM 8824 O O . HOH I 8 . ? 47.222 41.624 -14.647 1.00 30.52 ? 1351 HOH A O 1 HETATM 8825 O O . HOH I 8 . ? 51.809 41.059 -12.921 1.00 31.19 ? 1352 HOH A O 1 HETATM 8826 O O . HOH I 8 . ? 53.661 39.213 -12.093 1.00 38.31 ? 1353 HOH A O 1 HETATM 8827 O O . HOH I 8 . ? 53.424 34.186 -11.112 1.00 46.36 ? 1354 HOH A O 1 HETATM 8828 O O . HOH I 8 . ? 57.263 36.036 -14.207 1.00 38.08 ? 1355 HOH A O 1 HETATM 8829 O O . HOH I 8 . ? 58.607 34.971 -12.132 1.00 42.03 ? 1356 HOH A O 1 HETATM 8830 O O . HOH I 8 . ? 59.313 37.667 -15.354 1.00 28.44 ? 1357 HOH A O 1 HETATM 8831 O O . HOH I 8 . ? 58.051 37.441 -17.754 1.00 43.23 ? 1358 HOH A O 1 HETATM 8832 O O . HOH I 8 . ? 57.132 39.087 -19.405 1.00 42.47 ? 1359 HOH A O 1 HETATM 8833 O O . HOH I 8 . ? 57.193 43.139 -19.920 1.00 27.59 ? 1360 HOH A O 1 HETATM 8834 O O . HOH I 8 . ? 56.641 46.195 -17.348 1.00 17.40 ? 1361 HOH A O 1 HETATM 8835 O O . HOH I 8 . ? 60.873 46.943 -22.294 1.00 40.16 ? 1362 HOH A O 1 HETATM 8836 O O . HOH I 8 . ? 62.445 48.243 -20.797 1.00 40.79 ? 1363 HOH A O 1 HETATM 8837 O O . HOH I 8 . ? 64.590 49.700 -21.447 1.00 42.76 ? 1364 HOH A O 1 HETATM 8838 O O . HOH I 8 . ? 65.448 52.253 -21.828 1.00 47.96 ? 1365 HOH A O 1 HETATM 8839 O O . HOH I 8 . ? 66.654 56.243 -20.233 1.00 18.30 ? 1366 HOH A O 1 HETATM 8840 O O . HOH I 8 . ? 68.140 56.693 -22.390 1.00 35.67 ? 1367 HOH A O 1 HETATM 8841 O O . HOH I 8 . ? 70.224 55.318 -23.075 1.00 40.65 ? 1368 HOH A O 1 HETATM 8842 O O . HOH I 8 . ? 69.887 53.526 -19.601 1.00 42.20 ? 1369 HOH A O 1 HETATM 8843 O O . HOH I 8 . ? 67.754 54.823 -18.087 1.00 25.17 ? 1370 HOH A O 1 HETATM 8844 O O . HOH I 8 . ? 70.024 56.704 -17.537 1.00 49.94 ? 1371 HOH A O 1 HETATM 8845 O O . HOH I 8 . ? 69.441 59.082 -17.005 1.00 34.56 ? 1372 HOH A O 1 HETATM 8846 O O . HOH I 8 . ? 71.770 62.709 -17.862 1.00 27.26 ? 1373 HOH A O 1 HETATM 8847 O O . HOH I 8 . ? 70.333 61.886 -20.291 1.00 23.57 ? 1374 HOH A O 1 HETATM 8848 O O . HOH I 8 . ? 70.203 60.358 -23.223 1.00 36.78 ? 1375 HOH A O 1 HETATM 8849 O O . HOH I 8 . ? 69.922 62.950 -23.801 1.00 32.25 ? 1376 HOH A O 1 HETATM 8850 O O . HOH I 8 . ? 69.256 60.729 -27.283 1.00 43.97 ? 1377 HOH A O 1 HETATM 8851 O O . HOH I 8 . ? 66.926 60.030 -27.075 1.00 22.04 ? 1378 HOH A O 1 HETATM 8852 O O . HOH I 8 . ? 68.263 57.544 -26.875 1.00 47.52 ? 1379 HOH A O 1 HETATM 8853 O O . HOH I 8 . ? 67.887 56.567 -29.637 1.00 42.65 ? 1380 HOH A O 1 HETATM 8854 O O . HOH I 8 . ? 66.366 58.305 -31.112 1.00 43.76 ? 1381 HOH A O 1 HETATM 8855 O O . HOH I 8 . ? 61.428 54.115 -32.520 1.00 47.01 ? 1382 HOH A O 1 HETATM 8856 O O . HOH I 8 . ? 59.098 54.334 -33.199 1.00 35.63 ? 1383 HOH A O 1 HETATM 8857 O O . HOH I 8 . ? 59.999 52.937 -30.523 1.00 37.95 ? 1384 HOH A O 1 HETATM 8858 O O . HOH I 8 . ? 61.390 54.369 -28.863 1.00 24.35 ? 1385 HOH A O 1 HETATM 8859 O O . HOH I 8 . ? 62.547 51.886 -32.267 1.00 44.06 ? 1386 HOH A O 1 HETATM 8860 O O . HOH I 8 . ? 61.316 47.491 -26.721 1.00 54.86 ? 1387 HOH A O 1 HETATM 8861 O O . HOH I 8 . ? 58.621 44.086 -27.933 1.00 42.19 ? 1388 HOH A O 1 HETATM 8862 O O . HOH I 8 . ? 52.370 45.188 -27.009 1.00 37.44 ? 1389 HOH A O 1 HETATM 8863 O O . HOH I 8 . ? 53.337 47.153 -25.061 1.00 19.52 ? 1390 HOH A O 1 HETATM 8864 O O . HOH I 8 . ? 49.528 44.485 -21.455 1.00 33.34 ? 1391 HOH A O 1 HETATM 8865 O O . HOH I 8 . ? 46.106 40.688 -22.542 1.00 48.57 ? 1392 HOH A O 1 HETATM 8866 O O . HOH I 8 . ? 43.414 40.530 -22.893 1.00 36.26 ? 1393 HOH A O 1 HETATM 8867 O O . HOH I 8 . ? 43.498 42.753 -24.691 1.00 39.25 ? 1394 HOH A O 1 HETATM 8868 O O . HOH I 8 . ? 45.363 41.478 -26.168 1.00 57.02 ? 1395 HOH A O 1 HETATM 8869 O O . HOH I 8 . ? 41.506 44.668 -24.261 1.00 22.66 ? 1396 HOH A O 1 HETATM 8870 O O . HOH I 8 . ? 42.220 47.259 -24.466 1.00 15.75 ? 1397 HOH A O 1 HETATM 8871 O O . HOH I 8 . ? 43.231 46.168 -22.566 1.00 41.07 ? 1398 HOH A O 1 HETATM 8872 O O . HOH I 8 . ? 42.656 47.477 -27.165 1.00 31.48 ? 1399 HOH A O 1 HETATM 8873 O O . HOH I 8 . ? 40.934 48.092 -29.144 1.00 39.80 ? 1400 HOH A O 1 HETATM 8874 O O . HOH I 8 . ? 39.475 48.645 -32.808 1.00 24.97 ? 1401 HOH A O 1 HETATM 8875 O O . HOH I 8 . ? 38.740 45.087 -33.526 1.00 24.62 ? 1402 HOH A O 1 HETATM 8876 O O . HOH I 8 . ? 38.454 46.576 -39.977 1.00 41.65 ? 1403 HOH A O 1 HETATM 8877 O O . HOH I 8 . ? 31.778 51.072 -35.399 1.00 21.88 ? 1404 HOH A O 1 HETATM 8878 O O . HOH I 8 . ? 34.691 53.542 -33.135 1.00 37.02 ? 1405 HOH A O 1 HETATM 8879 O O . HOH I 8 . ? 35.630 55.458 -34.677 1.00 44.59 ? 1406 HOH A O 1 HETATM 8880 O O . HOH I 8 . ? 33.574 56.979 -35.909 1.00 18.39 ? 1407 HOH A O 1 HETATM 8881 O O . HOH I 8 . ? 34.769 59.380 -34.928 1.00 21.98 ? 1408 HOH A O 1 HETATM 8882 O O . HOH I 8 . ? 37.104 58.951 -33.355 1.00 29.07 ? 1409 HOH A O 1 HETATM 8883 O O . HOH I 8 . ? 37.711 61.350 -32.421 1.00 28.14 ? 1410 HOH A O 1 HETATM 8884 O O . HOH I 8 . ? 36.115 63.383 -33.870 1.00 37.45 ? 1411 HOH A O 1 HETATM 8885 O O . HOH I 8 . ? 34.056 64.366 -32.265 1.00 15.93 ? 1412 HOH A O 1 HETATM 8886 O O . HOH I 8 . ? 36.451 62.623 -38.434 1.00 34.06 ? 1413 HOH A O 1 HETATM 8887 O O . HOH I 8 . ? 37.188 63.071 -42.056 1.00 39.38 ? 1414 HOH A O 1 HETATM 8888 O O . HOH I 8 . ? 36.664 63.027 -45.380 1.00 58.76 ? 1415 HOH A O 1 HETATM 8889 O O . HOH I 8 . ? 34.627 65.986 -42.445 1.00 37.89 ? 1416 HOH A O 1 HETATM 8890 O O . HOH I 8 . ? 34.263 70.341 -44.808 1.00 45.31 ? 1417 HOH A O 1 HETATM 8891 O O . HOH I 8 . ? 30.984 69.221 -45.465 1.00 44.24 ? 1418 HOH A O 1 HETATM 8892 O O . HOH I 8 . ? 30.102 71.409 -44.764 1.00 48.66 ? 1419 HOH A O 1 HETATM 8893 O O . HOH I 8 . ? 29.048 72.065 -41.973 1.00 36.21 ? 1420 HOH A O 1 HETATM 8894 O O . HOH I 8 . ? 28.882 69.747 -39.529 1.00 24.24 ? 1421 HOH A O 1 HETATM 8895 O O . HOH I 8 . ? 24.785 71.550 -39.841 1.00 27.84 ? 1422 HOH A O 1 HETATM 8896 O O . HOH I 8 . ? 25.956 76.213 -38.977 1.00 32.35 ? 1423 HOH A O 1 HETATM 8897 O O . HOH I 8 . ? 27.367 76.377 -41.322 1.00 44.93 ? 1424 HOH A O 1 HETATM 8898 O O . HOH I 8 . ? 28.865 77.808 -43.424 1.00 51.63 ? 1425 HOH A O 1 HETATM 8899 O O . HOH I 8 . ? 31.320 79.000 -42.842 1.00 29.03 ? 1426 HOH A O 1 HETATM 8900 O O . HOH I 8 . ? 29.595 81.344 -42.943 1.00 38.55 ? 1427 HOH A O 1 HETATM 8901 O O . HOH I 8 . ? 26.134 81.585 -42.619 1.00 35.01 ? 1428 HOH A O 1 HETATM 8902 O O . HOH I 8 . ? 25.243 84.505 -44.095 1.00 41.88 ? 1429 HOH A O 1 HETATM 8903 O O . HOH I 8 . ? 23.557 84.870 -41.966 1.00 41.81 ? 1430 HOH A O 1 HETATM 8904 O O . HOH I 8 . ? 24.072 87.305 -40.970 1.00 40.25 ? 1431 HOH A O 1 HETATM 8905 O O . HOH I 8 . ? 25.947 87.504 -42.867 1.00 38.65 ? 1432 HOH A O 1 HETATM 8906 O O . HOH I 8 . ? 28.288 87.772 -41.741 1.00 27.78 ? 1433 HOH A O 1 HETATM 8907 O O . HOH I 8 . ? 28.440 90.446 -42.707 1.00 27.71 ? 1434 HOH A O 1 HETATM 8908 O O . HOH I 8 . ? 32.620 89.067 -43.198 1.00 27.28 ? 1435 HOH A O 1 HETATM 8909 O O . HOH I 8 . ? 34.148 86.806 -43.647 1.00 41.61 ? 1436 HOH A O 1 HETATM 8910 O O . HOH I 8 . ? 39.140 86.458 -41.645 1.00 28.12 ? 1437 HOH A O 1 HETATM 8911 O O . HOH I 8 . ? 41.042 86.671 -44.012 1.00 47.28 ? 1438 HOH A O 1 HETATM 8912 O O . HOH I 8 . ? 42.205 87.662 -41.015 1.00 14.69 ? 1439 HOH A O 1 HETATM 8913 O O . HOH I 8 . ? 43.710 88.335 -38.716 1.00 15.42 ? 1440 HOH A O 1 HETATM 8914 O O . HOH I 8 . ? 43.458 93.752 -37.738 1.00 22.89 ? 1441 HOH A O 1 HETATM 8915 O O . HOH I 8 . ? 41.293 94.798 -39.484 1.00 26.59 ? 1442 HOH A O 1 HETATM 8916 O O . HOH I 8 . ? 40.741 96.322 -37.406 1.00 25.44 ? 1443 HOH A O 1 HETATM 8917 O O . HOH I 8 . ? 43.203 98.057 -37.218 1.00 34.16 ? 1444 HOH A O 1 HETATM 8918 O O . HOH I 8 . ? 46.746 95.526 -37.164 1.00 42.18 ? 1445 HOH A O 1 HETATM 8919 O O . HOH I 8 . ? 48.588 93.957 -37.603 1.00 47.38 ? 1446 HOH A O 1 HETATM 8920 O O . HOH I 8 . ? 48.305 93.338 -42.812 1.00 57.70 ? 1447 HOH A O 1 HETATM 8921 O O . HOH I 8 . ? 45.342 91.480 -44.221 1.00 40.56 ? 1448 HOH A O 1 HETATM 8922 O O . HOH I 8 . ? 46.079 97.001 -43.898 1.00 24.74 ? 1449 HOH A O 1 HETATM 8923 O O . HOH I 8 . ? 42.274 96.317 -41.907 1.00 38.84 ? 1450 HOH A O 1 HETATM 8924 O O . HOH I 8 . ? 44.775 101.626 -33.051 1.00 43.35 ? 1451 HOH A O 1 HETATM 8925 O O . HOH I 8 . ? 47.101 99.779 -31.925 1.00 32.35 ? 1452 HOH A O 1 HETATM 8926 O O . HOH I 8 . ? 48.747 97.877 -33.555 1.00 27.39 ? 1453 HOH A O 1 HETATM 8927 O O A HOH I 8 . ? 52.397 98.523 -27.903 0.50 18.41 ? 1454 HOH A O 1 HETATM 8928 O O B HOH I 8 . ? 51.178 98.560 -29.448 0.50 21.93 ? 1454 HOH A O 1 HETATM 8929 O O . HOH I 8 . ? 48.642 95.254 -26.890 1.00 24.97 ? 1455 HOH A O 1 HETATM 8930 O O . HOH I 8 . ? 49.639 94.470 -24.635 1.00 39.46 ? 1456 HOH A O 1 HETATM 8931 O O . HOH I 8 . ? 49.275 91.837 -24.446 1.00 30.19 ? 1457 HOH A O 1 HETATM 8932 O O . HOH I 8 . ? 50.946 90.846 -21.690 1.00 45.92 ? 1458 HOH A O 1 HETATM 8933 O O . HOH I 8 . ? 52.770 92.012 -23.459 1.00 32.32 ? 1459 HOH A O 1 HETATM 8934 O O . HOH I 8 . ? 55.013 90.213 -23.579 1.00 26.56 ? 1460 HOH A O 1 HETATM 8935 O O . HOH I 8 . ? 56.351 90.959 -25.785 1.00 23.68 ? 1461 HOH A O 1 HETATM 8936 O O . HOH I 8 . ? 56.407 92.771 -29.514 1.00 26.54 ? 1462 HOH A O 1 HETATM 8937 O O . HOH I 8 . ? 55.292 93.380 -31.640 1.00 35.81 ? 1463 HOH A O 1 HETATM 8938 O O . HOH I 8 . ? 53.800 94.076 -33.306 1.00 33.05 ? 1464 HOH A O 1 HETATM 8939 O O . HOH I 8 . ? 58.021 94.729 -32.503 1.00 45.74 ? 1465 HOH A O 1 HETATM 8940 O O . HOH I 8 . ? 58.885 92.405 -32.064 1.00 34.64 ? 1466 HOH A O 1 HETATM 8941 O O . HOH I 8 . ? 60.423 91.088 -30.920 1.00 32.78 ? 1467 HOH A O 1 HETATM 8942 O O . HOH I 8 . ? 60.501 91.914 -28.622 1.00 32.92 ? 1468 HOH A O 1 HETATM 8943 O O . HOH I 8 . ? 61.604 92.417 -33.959 1.00 31.31 ? 1469 HOH A O 1 HETATM 8944 O O . HOH I 8 . ? 64.107 92.260 -34.146 1.00 25.81 ? 1470 HOH A O 1 HETATM 8945 O O . HOH I 8 . ? 64.306 90.713 -36.387 1.00 39.90 ? 1471 HOH A O 1 HETATM 8946 O O . HOH I 8 . ? 61.506 90.828 -37.058 1.00 34.50 ? 1472 HOH A O 1 HETATM 8947 O O . HOH I 8 . ? 59.663 91.119 -35.386 1.00 24.25 ? 1473 HOH A O 1 HETATM 8948 O O . HOH I 8 . ? 60.592 94.935 -35.210 1.00 47.18 ? 1474 HOH A O 1 HETATM 8949 O O . HOH I 8 . ? 65.191 94.167 -35.981 1.00 43.32 ? 1475 HOH A O 1 HETATM 8950 O O . HOH I 8 . ? 66.185 96.774 -35.651 1.00 41.85 ? 1476 HOH A O 1 HETATM 8951 O O . HOH I 8 . ? 69.897 98.519 -36.415 1.00 50.06 ? 1477 HOH A O 1 HETATM 8952 O O . HOH I 8 . ? 70.654 95.478 -35.133 1.00 46.43 ? 1478 HOH A O 1 HETATM 8953 O O . HOH I 8 . ? 72.422 95.701 -31.266 1.00 32.49 ? 1479 HOH A O 1 HETATM 8954 O O . HOH I 8 . ? 70.392 88.411 -35.705 1.00 42.66 ? 1480 HOH A O 1 HETATM 8955 O O . HOH I 8 . ? 68.023 88.183 -35.132 1.00 33.24 ? 1481 HOH A O 1 HETATM 8956 O O . HOH I 8 . ? 67.413 85.565 -36.016 1.00 35.50 ? 1482 HOH A O 1 HETATM 8957 O O . HOH I 8 . ? 69.386 83.889 -36.003 1.00 25.98 ? 1483 HOH A O 1 HETATM 8958 O O . HOH I 8 . ? 69.894 81.981 -33.844 1.00 35.97 ? 1484 HOH A O 1 HETATM 8959 O O . HOH I 8 . ? 68.426 79.659 -34.724 1.00 28.27 ? 1485 HOH A O 1 HETATM 8960 O O . HOH I 8 . ? 68.680 79.631 -37.403 1.00 40.32 ? 1486 HOH A O 1 HETATM 8961 O O . HOH I 8 . ? 67.610 77.256 -38.679 1.00 40.33 ? 1487 HOH A O 1 HETATM 8962 O O . HOH I 8 . ? 69.980 77.086 -38.022 1.00 38.73 ? 1488 HOH A O 1 HETATM 8963 O O . HOH I 8 . ? 71.516 76.554 -35.771 1.00 43.45 ? 1489 HOH A O 1 HETATM 8964 O O . HOH I 8 . ? 69.309 77.046 -34.196 1.00 30.47 ? 1490 HOH A O 1 HETATM 8965 O O . HOH I 8 . ? 68.075 75.076 -35.090 1.00 30.67 ? 1491 HOH A O 1 HETATM 8966 O O . HOH I 8 . ? 71.215 72.197 -34.078 1.00 38.25 ? 1492 HOH A O 1 HETATM 8967 O O . HOH I 8 . ? 71.826 73.875 -29.110 1.00 27.91 ? 1493 HOH A O 1 HETATM 8968 O O . HOH I 8 . ? 72.681 76.031 -27.122 1.00 37.93 ? 1494 HOH A O 1 HETATM 8969 O O . HOH I 8 . ? 75.534 76.627 -27.254 1.00 45.90 ? 1495 HOH A O 1 HETATM 8970 O O . HOH I 8 . ? 76.708 74.153 -26.685 1.00 32.67 ? 1496 HOH A O 1 HETATM 8971 O O . HOH I 8 . ? 74.819 77.459 -20.680 1.00 36.54 ? 1497 HOH A O 1 HETATM 8972 O O . HOH I 8 . ? 73.291 76.731 -18.349 1.00 27.71 ? 1498 HOH A O 1 HETATM 8973 O O . HOH I 8 . ? 74.319 78.191 -16.397 1.00 43.66 ? 1499 HOH A O 1 HETATM 8974 O O . HOH I 8 . ? 74.913 76.262 -14.241 1.00 25.45 ? 1500 HOH A O 1 HETATM 8975 O O . HOH I 8 . ? 75.598 73.873 -16.111 1.00 28.81 ? 1501 HOH A O 1 HETATM 8976 O O . HOH I 8 . ? 77.767 75.372 -17.262 1.00 34.33 ? 1502 HOH A O 1 HETATM 8977 O O . HOH I 8 . ? 79.977 73.809 -17.659 1.00 29.09 ? 1503 HOH A O 1 HETATM 8978 O O . HOH I 8 . ? 75.533 74.125 -19.346 1.00 23.93 ? 1504 HOH A O 1 HETATM 8979 O O . HOH I 8 . ? 77.636 75.866 -11.763 1.00 41.21 ? 1505 HOH A O 1 HETATM 8980 O O . HOH I 8 . ? 78.231 72.267 -10.129 1.00 31.86 ? 1506 HOH A O 1 HETATM 8981 O O . HOH I 8 . ? 78.785 68.982 -11.992 1.00 22.99 ? 1507 HOH A O 1 HETATM 8982 O O . HOH I 8 . ? 77.734 66.453 -11.812 1.00 33.07 ? 1508 HOH A O 1 HETATM 8983 O O . HOH I 8 . ? 77.651 65.174 -14.686 1.00 24.64 ? 1509 HOH A O 1 HETATM 8984 O O . HOH I 8 . ? 75.319 64.156 -16.234 1.00 33.71 ? 1510 HOH A O 1 HETATM 8985 O O . HOH I 8 . ? 74.619 63.517 -13.894 1.00 35.15 ? 1511 HOH A O 1 HETATM 8986 O O . HOH I 8 . ? 74.701 61.010 -13.159 1.00 42.44 ? 1512 HOH A O 1 HETATM 8987 O O . HOH I 8 . ? 74.316 60.014 -9.560 1.00 34.80 ? 1513 HOH A O 1 HETATM 8988 O O . HOH I 8 . ? 72.249 58.818 -11.173 1.00 25.94 ? 1514 HOH A O 1 HETATM 8989 O O . HOH I 8 . ? 70.272 56.402 -12.414 1.00 35.79 ? 1515 HOH A O 1 HETATM 8990 O O . HOH I 8 . ? 71.370 54.470 -13.780 1.00 33.51 ? 1516 HOH A O 1 HETATM 8991 O O . HOH I 8 . ? 74.005 53.864 -13.745 1.00 44.99 ? 1517 HOH A O 1 HETATM 8992 O O . HOH I 8 . ? 75.374 52.449 -15.687 1.00 40.71 ? 1518 HOH A O 1 HETATM 8993 O O . HOH I 8 . ? 74.495 53.149 -18.119 1.00 46.00 ? 1519 HOH A O 1 HETATM 8994 O O . HOH I 8 . ? 76.166 50.038 -16.829 1.00 44.97 ? 1520 HOH A O 1 HETATM 8995 O O . HOH I 8 . ? 74.488 48.932 -18.508 1.00 43.71 ? 1521 HOH A O 1 HETATM 8996 O O . HOH I 8 . ? 72.215 47.328 -17.772 1.00 35.29 ? 1522 HOH A O 1 HETATM 8997 O O . HOH I 8 . ? 70.696 45.497 -16.898 1.00 44.12 ? 1523 HOH A O 1 HETATM 8998 O O . HOH I 8 . ? 68.720 46.976 -16.558 1.00 31.19 ? 1524 HOH A O 1 HETATM 8999 O O . HOH I 8 . ? 71.136 43.193 -15.409 1.00 32.49 ? 1525 HOH A O 1 HETATM 9000 O O . HOH I 8 . ? 69.164 41.802 -17.314 1.00 33.31 ? 1526 HOH A O 1 HETATM 9001 O O . HOH I 8 . ? 74.678 44.333 -14.187 1.00 47.83 ? 1527 HOH A O 1 HETATM 9002 O O . HOH I 8 . ? 73.039 43.937 -12.087 1.00 42.22 ? 1528 HOH A O 1 HETATM 9003 O O . HOH I 8 . ? 76.562 47.023 -11.522 1.00 33.90 ? 1529 HOH A O 1 HETATM 9004 O O . HOH I 8 . ? 75.602 48.316 -5.420 1.00 52.14 ? 1530 HOH A O 1 HETATM 9005 O O . HOH I 8 . ? 73.664 46.323 -5.022 1.00 35.14 ? 1531 HOH A O 1 HETATM 9006 O O . HOH I 8 . ? 71.037 49.541 -0.061 1.00 25.26 ? 1532 HOH A O 1 HETATM 9007 O O . HOH I 8 . ? 72.247 47.823 1.214 1.00 43.05 ? 1533 HOH A O 1 HETATM 9008 O O . HOH I 8 . ? 72.822 50.540 1.432 1.00 43.25 ? 1534 HOH A O 1 HETATM 9009 O O . HOH I 8 . ? 74.363 52.330 1.755 1.00 33.43 ? 1535 HOH A O 1 HETATM 9010 O O . HOH I 8 . ? 76.721 51.238 2.629 1.00 50.85 ? 1536 HOH A O 1 HETATM 9011 O O . HOH I 8 . ? 79.825 51.501 -0.300 1.00 25.88 ? 1537 HOH A O 1 HETATM 9012 O O . HOH I 8 . ? 77.073 52.910 -7.359 1.00 38.05 ? 1538 HOH A O 1 HETATM 9013 O O . HOH I 8 . ? 76.717 54.087 -10.072 1.00 26.39 ? 1539 HOH A O 1 HETATM 9014 O O . HOH I 8 . ? 78.590 53.737 -12.017 1.00 35.27 ? 1540 HOH A O 1 HETATM 9015 O O . HOH I 8 . ? 78.581 53.008 -15.060 1.00 49.77 ? 1541 HOH A O 1 HETATM 9016 O O . HOH I 8 . ? 10.606 57.900 -20.903 1.00 42.54 ? 1542 HOH A O 1 HETATM 9017 O O . HOH I 8 . ? 9.688 60.380 -20.342 1.00 28.75 ? 1543 HOH A O 1 HETATM 9018 O O . HOH I 8 . ? 80.464 64.126 -21.287 1.00 22.63 ? 1544 HOH A O 1 HETATM 9019 O O . HOH I 8 . ? 80.724 63.577 -16.722 1.00 26.83 ? 1545 HOH A O 1 HETATM 9020 O O . HOH I 8 . ? 79.638 67.839 -15.099 1.00 37.41 ? 1546 HOH A O 1 HETATM 9021 O O . HOH I 8 . ? 84.453 68.268 -17.212 1.00 17.44 ? 1547 HOH A O 1 HETATM 9022 O O . HOH I 8 . ? 83.733 70.075 -20.057 1.00 27.12 ? 1548 HOH A O 1 HETATM 9023 O O . HOH I 8 . ? 83.582 70.386 -22.863 1.00 26.43 ? 1549 HOH A O 1 HETATM 9024 O O . HOH I 8 . ? 82.272 69.892 -25.206 1.00 38.94 ? 1550 HOH A O 1 HETATM 9025 O O . HOH I 8 . ? 84.347 68.472 -27.173 1.00 39.22 ? 1551 HOH A O 1 HETATM 9026 O O . HOH I 8 . ? 83.921 66.072 -24.985 1.00 43.16 ? 1552 HOH A O 1 HETATM 9027 O O . HOH I 8 . ? 83.656 67.450 -22.868 1.00 28.40 ? 1553 HOH A O 1 HETATM 9028 O O . HOH I 8 . ? 74.038 65.998 -17.527 1.00 17.24 ? 1554 HOH A O 1 HETATM 9029 O O . HOH I 8 . ? 72.904 64.144 -20.972 1.00 28.92 ? 1555 HOH A O 1 HETATM 9030 O O . HOH I 8 . ? 31.264 46.169 41.840 1.00 32.63 ? 1556 HOH A O 1 HETATM 9031 O O . HOH I 8 . ? 68.062 58.770 -24.071 1.00 19.17 ? 1557 HOH A O 1 HETATM 9032 O O . HOH I 8 . ? 60.529 61.008 -18.074 1.00 10.13 ? 1558 HOH A O 1 HETATM 9033 O O . HOH I 8 . ? 53.743 64.840 -19.803 1.00 8.91 ? 1559 HOH A O 1 HETATM 9034 O O . HOH I 8 . ? 51.801 69.939 -18.535 1.00 34.37 ? 1560 HOH A O 1 HETATM 9035 O O . HOH I 8 . ? 51.378 71.513 -20.335 1.00 20.87 ? 1561 HOH A O 1 HETATM 9036 O O . HOH I 8 . ? 53.645 72.642 -19.224 1.00 14.64 ? 1562 HOH A O 1 HETATM 9037 O O . HOH I 8 . ? 50.088 73.584 -21.707 1.00 29.24 ? 1563 HOH A O 1 HETATM 9038 O O . HOH I 8 . ? 48.472 71.764 -22.345 1.00 34.12 ? 1564 HOH A O 1 HETATM 9039 O O . HOH I 8 . ? 47.511 71.882 -19.967 1.00 33.17 ? 1565 HOH A O 1 HETATM 9040 O O . HOH I 8 . ? 45.906 70.729 -18.580 1.00 34.30 ? 1566 HOH A O 1 HETATM 9041 O O . HOH I 8 . ? 46.888 72.510 -17.442 1.00 28.93 ? 1567 HOH A O 1 HETATM 9042 O O . HOH I 8 . ? 49.630 70.905 -17.659 1.00 34.62 ? 1568 HOH A O 1 HETATM 9043 O O . HOH I 8 . ? 48.927 69.390 -15.505 1.00 25.70 ? 1569 HOH A O 1 HETATM 9044 O O . HOH I 8 . ? 46.510 67.644 -15.602 1.00 14.76 ? 1570 HOH A O 1 HETATM 9045 O O . HOH I 8 . ? 45.054 69.021 -17.156 1.00 21.33 ? 1571 HOH A O 1 HETATM 9046 O O . HOH I 8 . ? 42.233 75.275 -16.026 1.00 12.72 ? 1572 HOH A O 1 HETATM 9047 O O . HOH I 8 . ? 41.335 77.598 -14.097 1.00 12.78 ? 1573 HOH A O 1 HETATM 9048 O O . HOH I 8 . ? 40.382 82.825 -10.677 1.00 15.93 ? 1574 HOH A O 1 HETATM 9049 O O . HOH I 8 . ? 42.983 82.308 -9.950 1.00 24.68 ? 1575 HOH A O 1 HETATM 9050 O O . HOH I 8 . ? 43.883 83.190 -7.850 1.00 44.94 ? 1576 HOH A O 1 HETATM 9051 O O . HOH I 8 . ? 44.921 84.265 -10.672 1.00 45.25 ? 1577 HOH A O 1 HETATM 9052 O O . HOH I 8 . ? 47.548 81.134 -9.277 1.00 61.00 ? 1578 HOH A O 1 HETATM 9053 O O . HOH I 8 . ? 45.770 79.228 -7.962 1.00 23.41 ? 1579 HOH A O 1 HETATM 9054 O O . HOH I 8 . ? 48.397 78.057 -9.721 1.00 27.36 ? 1580 HOH A O 1 HETATM 9055 O O . HOH I 8 . ? 49.968 79.937 -11.139 1.00 41.79 ? 1581 HOH A O 1 HETATM 9056 O O . HOH I 8 . ? 50.583 79.125 -15.670 1.00 25.83 ? 1582 HOH A O 1 HETATM 9057 O O . HOH I 8 . ? 52.524 79.100 -17.609 1.00 20.13 ? 1583 HOH A O 1 HETATM 9058 O O . HOH I 8 . ? 55.115 80.579 -19.362 1.00 26.10 ? 1584 HOH A O 1 HETATM 9059 O O . HOH I 8 . ? 57.378 80.208 -18.095 1.00 32.04 ? 1585 HOH A O 1 HETATM 9060 O O . HOH I 8 . ? 56.266 78.844 -14.622 1.00 27.22 ? 1586 HOH A O 1 HETATM 9061 O O . HOH I 8 . ? 57.066 80.071 -11.061 1.00 40.60 ? 1587 HOH A O 1 HETATM 9062 O O . HOH I 8 . ? 57.324 80.446 -8.425 1.00 46.73 ? 1588 HOH A O 1 HETATM 9063 O O . HOH I 8 . ? 59.393 78.925 -7.764 1.00 38.19 ? 1589 HOH A O 1 HETATM 9064 O O . HOH I 8 . ? 59.627 76.524 -8.969 1.00 14.89 ? 1590 HOH A O 1 HETATM 9065 O O . HOH I 8 . ? 61.917 76.341 -10.487 1.00 17.12 ? 1591 HOH A O 1 HETATM 9066 O O . HOH I 8 . ? 61.437 77.522 -12.880 1.00 19.22 ? 1592 HOH A O 1 HETATM 9067 O O . HOH I 8 . ? 60.784 79.996 -11.972 1.00 38.07 ? 1593 HOH A O 1 HETATM 9068 O O . HOH I 8 . ? 60.950 80.555 -9.268 1.00 46.29 ? 1594 HOH A O 1 HETATM 9069 O O . HOH I 8 . ? 62.785 79.044 -6.542 1.00 48.22 ? 1595 HOH A O 1 HETATM 9070 O O . HOH I 8 . ? 65.374 78.845 -5.828 1.00 28.04 ? 1596 HOH A O 1 HETATM 9071 O O . HOH I 8 . ? 65.540 76.677 -3.499 1.00 38.08 ? 1597 HOH A O 1 HETATM 9072 O O . HOH I 8 . ? 66.879 74.375 -4.371 1.00 26.49 ? 1598 HOH A O 1 HETATM 9073 O O . HOH I 8 . ? 69.533 73.880 -3.320 1.00 47.18 ? 1599 HOH A O 1 HETATM 9074 O O . HOH I 8 . ? 73.749 74.058 -5.718 1.00 24.80 ? 1600 HOH A O 1 HETATM 9075 O O . HOH I 8 . ? 75.351 76.238 -6.022 1.00 50.15 ? 1601 HOH A O 1 HETATM 9076 O O . HOH I 8 . ? 72.089 80.750 -4.596 1.00 43.55 ? 1602 HOH A O 1 HETATM 9077 O O . HOH I 8 . ? 70.762 79.050 -2.802 1.00 38.55 ? 1603 HOH A O 1 HETATM 9078 O O . HOH I 8 . ? 64.538 77.403 0.358 1.00 33.19 ? 1604 HOH A O 1 HETATM 9079 O O . HOH I 8 . ? 64.169 70.710 -5.271 1.00 16.08 ? 1605 HOH A O 1 HETATM 9080 O O . HOH I 8 . ? 66.454 71.508 -6.766 1.00 19.39 ? 1606 HOH A O 1 HETATM 9081 O O . HOH I 8 . ? 68.004 65.542 -3.375 1.00 15.02 ? 1607 HOH A O 1 HETATM 9082 O O . HOH I 8 . ? 65.920 66.183 -0.375 1.00 25.05 ? 1608 HOH A O 1 HETATM 9083 O O . HOH I 8 . ? 68.039 67.031 1.098 1.00 38.08 ? 1609 HOH A O 1 HETATM 9084 O O . HOH I 8 . ? 66.397 68.603 2.009 1.00 34.86 ? 1610 HOH A O 1 HETATM 9085 O O . HOH I 8 . ? 69.277 63.762 1.827 1.00 45.33 ? 1611 HOH A O 1 HETATM 9086 O O . HOH I 8 . ? 70.451 62.016 0.090 1.00 37.21 ? 1612 HOH A O 1 HETATM 9087 O O . HOH I 8 . ? 71.305 59.774 1.103 1.00 36.02 ? 1613 HOH A O 1 HETATM 9088 O O . HOH I 8 . ? 73.518 62.893 -0.793 1.00 42.61 ? 1614 HOH A O 1 HETATM 9089 O O . HOH I 8 . ? 69.243 61.424 -2.351 1.00 16.31 ? 1615 HOH A O 1 HETATM 9090 O O . HOH I 8 . ? 67.566 60.701 -5.632 1.00 12.46 ? 1616 HOH A O 1 HETATM 9091 O O . HOH I 8 . ? 65.724 60.332 -7.663 1.00 10.24 ? 1617 HOH A O 1 HETATM 9092 O O . HOH I 8 . ? 63.210 61.325 -7.553 1.00 9.30 ? 1618 HOH A O 1 HETATM 9093 O O . HOH I 8 . ? 63.159 61.124 -4.812 1.00 14.37 ? 1619 HOH A O 1 HETATM 9094 O O . HOH I 8 . ? 60.711 60.890 -3.578 1.00 12.67 ? 1620 HOH A O 1 HETATM 9095 O O . HOH I 8 . ? 60.585 62.262 -1.271 1.00 12.33 ? 1621 HOH A O 1 HETATM 9096 O O . HOH I 8 . ? 62.207 60.794 0.526 1.00 29.80 ? 1622 HOH A O 1 HETATM 9097 O O . HOH I 8 . ? 63.239 58.685 -1.367 1.00 15.90 ? 1623 HOH A O 1 HETATM 9098 O O . HOH I 8 . ? 63.768 57.146 0.844 1.00 28.85 ? 1624 HOH A O 1 HETATM 9099 O O . HOH I 8 . ? 61.036 56.163 2.067 1.00 33.27 ? 1625 HOH A O 1 HETATM 9100 O O . HOH I 8 . ? 59.649 57.617 3.363 1.00 33.30 ? 1626 HOH A O 1 HETATM 9101 O O . HOH I 8 . ? 59.062 58.218 0.981 1.00 25.35 ? 1627 HOH A O 1 HETATM 9102 O O . HOH I 8 . ? 56.491 58.548 1.365 1.00 27.40 ? 1628 HOH A O 1 HETATM 9103 O O . HOH I 8 . ? 55.073 57.638 -0.476 1.00 15.52 ? 1629 HOH A O 1 HETATM 9104 O O . HOH I 8 . ? 56.419 55.805 -2.118 1.00 10.74 ? 1630 HOH A O 1 HETATM 9105 O O . HOH I 8 . ? 58.927 56.788 -1.380 1.00 12.56 ? 1631 HOH A O 1 HETATM 9106 O O . HOH I 8 . ? 60.806 58.290 -2.774 1.00 12.21 ? 1632 HOH A O 1 HETATM 9107 O O . HOH I 8 . ? 60.582 54.835 -0.276 1.00 14.63 ? 1633 HOH A O 1 HETATM 9108 O O . HOH I 8 . ? 58.806 52.674 -0.084 1.00 13.61 ? 1634 HOH A O 1 HETATM 9109 O O . HOH I 8 . ? 59.337 50.075 -0.631 1.00 16.76 ? 1635 HOH A O 1 HETATM 9110 O O . HOH I 8 . ? 59.473 49.030 2.306 1.00 39.85 ? 1636 HOH A O 1 HETATM 9111 O O . HOH I 8 . ? 59.410 52.068 2.620 1.00 28.96 ? 1637 HOH A O 1 HETATM 9112 O O . HOH I 8 . ? 58.481 52.843 4.737 1.00 28.60 ? 1638 HOH A O 1 HETATM 9113 O O . HOH I 8 . ? 60.174 54.964 4.299 1.00 41.09 ? 1639 HOH A O 1 HETATM 9114 O O . HOH I 8 . ? 60.418 51.599 6.173 1.00 37.53 ? 1640 HOH A O 1 HETATM 9115 O O . HOH I 8 . ? 62.060 51.641 9.495 1.00 41.34 ? 1641 HOH A O 1 HETATM 9116 O O . HOH I 8 . ? 60.407 51.323 12.866 1.00 39.39 ? 1642 HOH A O 1 HETATM 9117 O O . HOH I 8 . ? 58.888 51.237 14.896 1.00 40.68 ? 1643 HOH A O 1 HETATM 9118 O O . HOH I 8 . ? 57.652 49.290 16.669 1.00 32.95 ? 1644 HOH A O 1 HETATM 9119 O O . HOH I 8 . ? 55.298 50.424 16.878 1.00 29.14 ? 1645 HOH A O 1 HETATM 9120 O O . HOH I 8 . ? 54.420 47.778 15.598 1.00 26.81 ? 1646 HOH A O 1 HETATM 9121 O O . HOH I 8 . ? 56.976 46.790 15.767 1.00 31.12 ? 1647 HOH A O 1 HETATM 9122 O O . HOH I 8 . ? 58.968 48.865 19.079 1.00 34.99 ? 1648 HOH A O 1 HETATM 9123 O O . HOH I 8 . ? 60.385 50.837 20.307 1.00 34.34 ? 1649 HOH A O 1 HETATM 9124 O O . HOH I 8 . ? 60.262 46.322 18.987 1.00 49.76 ? 1650 HOH A O 1 HETATM 9125 O O . HOH I 8 . ? 58.862 42.144 16.841 1.00 50.69 ? 1651 HOH A O 1 HETATM 9126 O O . HOH I 8 . ? 52.641 43.808 17.145 1.00 41.89 ? 1652 HOH A O 1 HETATM 9127 O O . HOH I 8 . ? 49.120 44.052 17.730 1.00 52.69 ? 1653 HOH A O 1 HETATM 9128 O O . HOH I 8 . ? 46.088 46.235 16.493 1.00 30.75 ? 1654 HOH A O 1 HETATM 9129 O O . HOH I 8 . ? 48.121 48.424 16.483 1.00 16.08 ? 1655 HOH A O 1 HETATM 9130 O O . HOH I 8 . ? 48.032 49.603 13.876 1.00 12.68 ? 1656 HOH A O 1 HETATM 9131 O O . HOH I 8 . ? 47.144 48.689 11.568 1.00 15.71 ? 1657 HOH A O 1 HETATM 9132 O O . HOH I 8 . ? 43.145 48.127 11.294 1.00 12.64 ? 1658 HOH A O 1 HETATM 9133 O O . HOH I 8 . ? 44.878 40.421 13.379 1.00 31.76 ? 1659 HOH A O 1 HETATM 9134 O O . HOH I 8 . ? 41.897 39.190 16.694 1.00 27.75 ? 1660 HOH A O 1 HETATM 9135 O O . HOH I 8 . ? 39.279 38.977 17.318 1.00 17.01 ? 1661 HOH A O 1 HETATM 9136 O O . HOH I 8 . ? 43.932 45.089 19.241 1.00 39.58 ? 1662 HOH A O 1 HETATM 9137 O O . HOH I 8 . ? 45.740 45.128 23.129 1.00 30.87 ? 1663 HOH A O 1 HETATM 9138 O O . HOH I 8 . ? 44.447 45.487 25.374 1.00 33.09 ? 1664 HOH A O 1 HETATM 9139 O O . HOH I 8 . ? 49.181 42.359 22.733 1.00 44.59 ? 1665 HOH A O 1 HETATM 9140 O O . HOH I 8 . ? 43.353 41.237 30.445 1.00 26.53 ? 1666 HOH A O 1 HETATM 9141 O O . HOH I 8 . ? 37.688 40.522 26.524 1.00 30.47 ? 1667 HOH A O 1 HETATM 9142 O O . HOH I 8 . ? 37.196 37.492 25.012 1.00 44.94 ? 1668 HOH A O 1 HETATM 9143 O O . HOH I 8 . ? 30.294 36.669 29.042 1.00 25.75 ? 1669 HOH A O 1 HETATM 9144 O O . HOH I 8 . ? 27.346 35.112 29.629 1.00 27.01 ? 1670 HOH A O 1 HETATM 9145 O O . HOH I 8 . ? 26.440 37.487 29.483 1.00 18.72 ? 1671 HOH A O 1 HETATM 9146 O O . HOH I 8 . ? 28.324 34.884 32.275 1.00 35.57 ? 1672 HOH A O 1 HETATM 9147 O O . HOH I 8 . ? 27.524 31.038 30.251 1.00 37.29 ? 1673 HOH A O 1 HETATM 9148 O O . HOH I 8 . ? 26.287 32.884 28.782 1.00 25.87 ? 1674 HOH A O 1 HETATM 9149 O O . HOH I 8 . ? 22.615 31.427 29.702 1.00 27.25 ? 1675 HOH A O 1 HETATM 9150 O O . HOH I 8 . ? 20.872 31.782 31.578 1.00 40.96 ? 1676 HOH A O 1 HETATM 9151 O O . HOH I 8 . ? 18.563 34.203 29.480 1.00 47.49 ? 1677 HOH A O 1 HETATM 9152 O O . HOH I 8 . ? 19.990 35.728 25.694 1.00 30.41 ? 1678 HOH A O 1 HETATM 9153 O O . HOH I 8 . ? 18.908 36.821 22.637 1.00 42.08 ? 1679 HOH A O 1 HETATM 9154 O O . HOH I 8 . ? 18.518 37.687 19.780 1.00 39.14 ? 1680 HOH A O 1 HETATM 9155 O O . HOH I 8 . ? 19.734 39.316 17.712 1.00 17.52 ? 1681 HOH A O 1 HETATM 9156 O O . HOH I 8 . ? 21.611 38.059 15.631 1.00 35.65 ? 1682 HOH A O 1 HETATM 9157 O O . HOH I 8 . ? 22.987 36.949 13.354 1.00 36.01 ? 1683 HOH A O 1 HETATM 9158 O O . HOH I 8 . ? 22.176 34.604 12.655 1.00 49.50 ? 1684 HOH A O 1 HETATM 9159 O O . HOH I 8 . ? 25.414 33.283 13.362 1.00 32.52 ? 1685 HOH A O 1 HETATM 9160 O O . HOH I 8 . ? 24.282 34.500 15.733 1.00 37.21 ? 1686 HOH A O 1 HETATM 9161 O O . HOH I 8 . ? 21.590 32.064 15.531 1.00 43.10 ? 1687 HOH A O 1 HETATM 9162 O O . HOH I 8 . ? 20.766 30.435 17.891 1.00 35.24 ? 1688 HOH A O 1 HETATM 9163 O O . HOH I 8 . ? 16.021 30.894 18.126 1.00 51.78 ? 1689 HOH A O 1 HETATM 9164 O O . HOH I 8 . ? 16.327 33.534 15.870 1.00 43.47 ? 1690 HOH A O 1 HETATM 9165 O O . HOH I 8 . ? 16.141 36.400 16.222 1.00 28.80 ? 1691 HOH A O 1 HETATM 9166 O O . HOH I 8 . ? 17.966 34.938 13.349 1.00 41.34 ? 1692 HOH A O 1 HETATM 9167 O O . HOH I 8 . ? 18.202 37.709 11.495 1.00 36.36 ? 1693 HOH A O 1 HETATM 9168 O O . HOH I 8 . ? 20.518 37.889 12.303 1.00 28.74 ? 1694 HOH A O 1 HETATM 9169 O O . HOH I 8 . ? 25.055 40.114 14.285 1.00 19.92 ? 1695 HOH A O 1 HETATM 9170 O O . HOH I 8 . ? 27.231 41.450 13.369 1.00 15.68 ? 1696 HOH A O 1 HETATM 9171 O O . HOH I 8 . ? 28.324 43.943 13.248 1.00 9.88 ? 1697 HOH A O 1 HETATM 9172 O O . HOH I 8 . ? 27.214 46.418 13.665 1.00 15.65 ? 1698 HOH A O 1 HETATM 9173 O O . HOH I 8 . ? 27.983 48.634 12.184 1.00 15.28 ? 1699 HOH A O 1 HETATM 9174 O O A HOH I 8 . ? 25.801 52.181 12.969 0.50 14.15 ? 1700 HOH A O 1 HETATM 9175 O O B HOH I 8 . ? 27.448 50.977 13.321 0.50 9.91 ? 1700 HOH A O 1 HETATM 9176 O O . HOH I 8 . ? 25.546 53.757 11.245 1.00 15.33 ? 1701 HOH A O 1 HETATM 9177 O O . HOH I 8 . ? 19.390 55.314 11.610 1.00 12.56 ? 1702 HOH A O 1 HETATM 9178 O O . HOH I 8 . ? 18.404 55.005 14.179 1.00 12.43 ? 1703 HOH A O 1 HETATM 9179 O O . HOH I 8 . ? 20.171 54.813 16.169 1.00 11.16 ? 1704 HOH A O 1 HETATM 9180 O O . HOH I 8 . ? 16.783 57.136 13.048 1.00 15.09 ? 1705 HOH A O 1 HETATM 9181 O O . HOH I 8 . ? 17.086 56.357 10.375 1.00 12.42 ? 1706 HOH A O 1 HETATM 9182 O O . HOH I 8 . ? 15.571 60.445 15.537 1.00 16.29 ? 1707 HOH A O 1 HETATM 9183 O O . HOH I 8 . ? 13.953 62.488 14.674 1.00 26.33 ? 1708 HOH A O 1 HETATM 9184 O O . HOH I 8 . ? 13.313 62.979 11.952 1.00 30.26 ? 1709 HOH A O 1 HETATM 9185 O O . HOH I 8 . ? 14.043 58.319 16.364 1.00 16.64 ? 1710 HOH A O 1 HETATM 9186 O O . HOH I 8 . ? 14.063 57.737 19.120 1.00 19.61 ? 1711 HOH A O 1 HETATM 9187 O O . HOH I 8 . ? 11.681 58.458 20.177 1.00 31.51 ? 1712 HOH A O 1 HETATM 9188 O O . HOH I 8 . ? 12.249 60.982 20.490 1.00 51.28 ? 1713 HOH A O 1 HETATM 9189 O O . HOH I 8 . ? 11.930 62.245 23.336 1.00 34.59 ? 1714 HOH A O 1 HETATM 9190 O O . HOH I 8 . ? 11.220 59.595 27.805 1.00 48.76 ? 1715 HOH A O 1 HETATM 9191 O O . HOH I 8 . ? 12.693 57.413 28.584 1.00 36.80 ? 1716 HOH A O 1 HETATM 9192 O O . HOH I 8 . ? 14.761 55.928 27.393 1.00 26.54 ? 1717 HOH A O 1 HETATM 9193 O O . HOH I 8 . ? 14.229 53.902 28.991 1.00 47.01 ? 1718 HOH A O 1 HETATM 9194 O O . HOH I 8 . ? 16.271 55.576 30.246 1.00 34.15 ? 1719 HOH A O 1 HETATM 9195 O O . HOH I 8 . ? 16.085 57.785 31.662 1.00 38.47 ? 1720 HOH A O 1 HETATM 9196 O O . HOH I 8 . ? 18.326 59.658 31.795 1.00 35.67 ? 1721 HOH A O 1 HETATM 9197 O O . HOH I 8 . ? 20.013 62.487 34.874 1.00 42.87 ? 1722 HOH A O 1 HETATM 9198 O O . HOH I 8 . ? 22.318 62.790 33.798 1.00 31.54 ? 1723 HOH A O 1 HETATM 9199 O O . HOH I 8 . ? 22.249 65.735 32.246 1.00 27.92 ? 1724 HOH A O 1 HETATM 9200 O O . HOH I 8 . ? 22.566 65.989 29.397 1.00 30.25 ? 1725 HOH A O 1 HETATM 9201 O O . HOH I 8 . ? 20.771 65.457 27.475 1.00 26.67 ? 1726 HOH A O 1 HETATM 9202 O O . HOH I 8 . ? 23.042 69.452 29.177 1.00 58.30 ? 1727 HOH A O 1 HETATM 9203 O O . HOH I 8 . ? 24.335 71.532 27.171 1.00 36.67 ? 1728 HOH A O 1 HETATM 9204 O O . HOH I 8 . ? 23.629 71.482 24.925 1.00 34.12 ? 1729 HOH A O 1 HETATM 9205 O O . HOH I 8 . ? 25.189 71.326 22.616 1.00 35.06 ? 1730 HOH A O 1 HETATM 9206 O O . HOH I 8 . ? 24.829 68.379 21.893 1.00 20.77 ? 1731 HOH A O 1 HETATM 9207 O O . HOH I 8 . ? 22.484 68.319 20.439 1.00 27.50 ? 1732 HOH A O 1 HETATM 9208 O O . HOH I 8 . ? 20.565 68.399 22.282 1.00 27.56 ? 1733 HOH A O 1 HETATM 9209 O O . HOH I 8 . ? 21.903 70.950 19.216 1.00 44.27 ? 1734 HOH A O 1 HETATM 9210 O O . HOH I 8 . ? 26.464 66.990 19.829 1.00 27.27 ? 1735 HOH A O 1 HETATM 9211 O O . HOH I 8 . ? 28.377 69.655 19.040 1.00 50.65 ? 1736 HOH A O 1 HETATM 9212 O O . HOH I 8 . ? 30.779 71.225 21.252 1.00 32.04 ? 1737 HOH A O 1 HETATM 9213 O O . HOH I 8 . ? 28.811 72.621 22.532 1.00 24.18 ? 1738 HOH A O 1 HETATM 9214 O O . HOH I 8 . ? 27.781 67.815 28.252 1.00 19.40 ? 1739 HOH A O 1 HETATM 9215 O O . HOH I 8 . ? 28.959 64.567 30.133 1.00 21.89 ? 1740 HOH A O 1 HETATM 9216 O O . HOH I 8 . ? 29.432 65.802 32.426 1.00 42.06 ? 1741 HOH A O 1 HETATM 9217 O O . HOH I 8 . ? 27.782 67.527 33.820 1.00 51.48 ? 1742 HOH A O 1 HETATM 9218 O O . HOH I 8 . ? 30.793 61.900 35.613 1.00 45.69 ? 1743 HOH A O 1 HETATM 9219 O O . HOH I 8 . ? 30.090 59.400 35.165 1.00 32.11 ? 1744 HOH A O 1 HETATM 9220 O O . HOH I 8 . ? 31.527 57.551 37.413 1.00 28.13 ? 1745 HOH A O 1 HETATM 9221 O O . HOH I 8 . ? 30.489 57.485 39.863 1.00 37.80 ? 1746 HOH A O 1 HETATM 9222 O O . HOH I 8 . ? 28.903 55.295 39.975 1.00 30.84 ? 1747 HOH A O 1 HETATM 9223 O O . HOH I 8 . ? 28.218 54.784 42.321 1.00 37.25 ? 1748 HOH A O 1 HETATM 9224 O O . HOH I 8 . ? 27.834 52.218 42.518 1.00 36.88 ? 1749 HOH A O 1 HETATM 9225 O O . HOH I 8 . ? 30.256 51.556 39.870 1.00 54.75 ? 1750 HOH A O 1 HETATM 9226 O O . HOH I 8 . ? 28.376 49.356 38.502 1.00 29.17 ? 1751 HOH A O 1 HETATM 9227 O O . HOH I 8 . ? 29.233 47.032 37.171 1.00 21.25 ? 1752 HOH A O 1 HETATM 9228 O O . HOH I 8 . ? 31.719 47.560 38.009 1.00 39.47 ? 1753 HOH A O 1 HETATM 9229 O O . HOH I 8 . ? 33.102 49.465 39.746 1.00 40.32 ? 1754 HOH A O 1 HETATM 9230 O O . HOH I 8 . ? 33.862 45.949 40.484 1.00 26.95 ? 1755 HOH A O 1 HETATM 9231 O O . HOH I 8 . ? 30.683 43.949 40.487 1.00 51.04 ? 1756 HOH A O 1 HETATM 9232 O O . HOH I 8 . ? 28.317 44.484 38.240 1.00 28.47 ? 1757 HOH A O 1 HETATM 9233 O O . HOH I 8 . ? 28.135 40.550 38.657 1.00 39.63 ? 1758 HOH A O 1 HETATM 9234 O O . HOH I 8 . ? 31.425 40.720 38.289 1.00 37.99 ? 1759 HOH A O 1 HETATM 9235 O O . HOH I 8 . ? 67.250 66.449 -32.725 1.00 42.68 ? 1760 HOH A O 1 HETATM 9236 O O . HOH I 8 . ? 34.850 45.871 33.285 1.00 18.73 ? 1761 HOH A O 1 HETATM 9237 O O . HOH I 8 . ? 34.237 47.985 36.442 1.00 36.27 ? 1762 HOH A O 1 HETATM 9238 O O . HOH I 8 . ? 34.597 51.241 36.006 1.00 33.91 ? 1763 HOH A O 1 HETATM 9239 O O . HOH I 8 . ? 39.525 49.838 36.365 1.00 33.45 ? 1764 HOH A O 1 HETATM 9240 O O . HOH I 8 . ? 40.163 52.741 36.391 1.00 29.75 ? 1765 HOH A O 1 HETATM 9241 O O . HOH I 8 . ? 42.672 53.366 35.614 1.00 21.08 ? 1766 HOH A O 1 HETATM 9242 O O . HOH I 8 . ? 43.831 56.653 33.772 1.00 28.53 ? 1767 HOH A O 1 HETATM 9243 O O . HOH I 8 . ? 45.581 58.047 32.381 1.00 36.29 ? 1768 HOH A O 1 HETATM 9244 O O . HOH I 8 . ? 41.895 58.385 34.527 1.00 34.47 ? 1769 HOH A O 1 HETATM 9245 O O . HOH I 8 . ? 37.928 62.448 35.453 1.00 33.27 ? 1770 HOH A O 1 HETATM 9246 O O . HOH I 8 . ? 35.588 62.361 34.096 1.00 25.37 ? 1771 HOH A O 1 HETATM 9247 O O . HOH I 8 . ? 33.744 64.213 33.394 1.00 59.53 ? 1772 HOH A O 1 HETATM 9248 O O . HOH I 8 . ? 34.185 59.950 35.000 1.00 38.70 ? 1773 HOH A O 1 HETATM 9249 O O . HOH I 8 . ? 35.810 59.019 36.668 1.00 47.59 ? 1774 HOH A O 1 HETATM 9250 O O . HOH I 8 . ? 26.799 57.585 40.510 1.00 39.67 ? 1775 HOH A O 1 HETATM 9251 O O . HOH I 8 . ? 24.346 57.425 38.706 1.00 28.28 ? 1776 HOH A O 1 HETATM 9252 O O . HOH I 8 . ? 21.178 58.563 37.776 1.00 41.37 ? 1777 HOH A O 1 HETATM 9253 O O . HOH I 8 . ? 21.560 55.606 40.088 1.00 26.14 ? 1778 HOH A O 1 HETATM 9254 O O . HOH I 8 . ? 26.416 56.713 43.341 1.00 43.36 ? 1779 HOH A O 1 HETATM 9255 O O . HOH I 8 . ? 24.249 60.949 36.139 1.00 35.21 ? 1780 HOH A O 1 HETATM 9256 O O . HOH I 8 . ? 23.215 56.094 30.897 1.00 18.16 ? 1781 HOH A O 1 HETATM 9257 O O . HOH I 8 . ? 17.577 52.632 33.099 1.00 39.47 ? 1782 HOH A O 1 HETATM 9258 O O . HOH I 8 . ? 17.898 52.809 35.902 1.00 36.04 ? 1783 HOH A O 1 HETATM 9259 O O . HOH I 8 . ? 17.885 50.860 38.456 1.00 35.99 ? 1784 HOH A O 1 HETATM 9260 O O . HOH I 8 . ? 19.081 48.715 37.812 1.00 20.84 ? 1785 HOH A O 1 HETATM 9261 O O . HOH I 8 . ? 21.131 47.591 39.089 1.00 22.63 ? 1786 HOH A O 1 HETATM 9262 O O . HOH I 8 . ? 19.933 45.518 40.373 1.00 31.48 ? 1787 HOH A O 1 HETATM 9263 O O . HOH I 8 . ? 17.672 46.817 39.740 1.00 45.11 ? 1788 HOH A O 1 HETATM 9264 O O . HOH I 8 . ? 17.756 49.254 41.258 1.00 21.36 ? 1789 HOH A O 1 HETATM 9265 O O . HOH I 8 . ? 24.263 45.789 40.724 1.00 43.29 ? 1790 HOH A O 1 HETATM 9266 O O . HOH I 8 . ? 27.591 47.653 45.959 1.00 43.96 ? 1791 HOH A O 1 HETATM 9267 O O . HOH I 8 . ? 21.206 41.824 35.336 1.00 27.69 ? 1792 HOH A O 1 HETATM 9268 O O . HOH I 8 . ? 19.848 43.399 34.010 1.00 25.98 ? 1793 HOH A O 1 HETATM 9269 O O . HOH I 8 . ? 17.326 41.857 32.282 1.00 45.21 ? 1794 HOH A O 1 HETATM 9270 O O . HOH I 8 . ? 18.336 43.082 27.487 1.00 28.79 ? 1795 HOH A O 1 HETATM 9271 O O . HOH I 8 . ? 18.150 41.779 25.301 1.00 31.10 ? 1796 HOH A O 1 HETATM 9272 O O . HOH I 8 . ? 19.081 39.964 26.673 1.00 32.90 ? 1797 HOH A O 1 HETATM 9273 O O . HOH I 8 . ? 14.132 44.798 27.128 1.00 40.07 ? 1798 HOH A O 1 HETATM 9274 O O . HOH I 8 . ? 14.884 47.223 27.532 1.00 39.15 ? 1799 HOH A O 1 HETATM 9275 O O . HOH I 8 . ? 13.834 48.963 29.103 1.00 38.64 ? 1800 HOH A O 1 HETATM 9276 O O . HOH I 8 . ? 15.792 49.228 31.461 1.00 23.82 ? 1801 HOH A O 1 HETATM 9277 O O . HOH I 8 . ? 15.053 51.283 32.619 1.00 26.78 ? 1802 HOH A O 1 HETATM 9278 O O . HOH I 8 . ? 14.582 47.109 32.348 1.00 26.06 ? 1803 HOH A O 1 HETATM 9279 O O . HOH I 8 . ? 12.384 47.546 31.427 1.00 33.76 ? 1804 HOH A O 1 HETATM 9280 O O . HOH I 8 . ? 13.476 52.747 26.091 1.00 34.77 ? 1805 HOH A O 1 HETATM 9281 O O . HOH I 8 . ? 13.032 55.220 25.324 1.00 37.85 ? 1806 HOH A O 1 HETATM 9282 O O . HOH I 8 . ? 12.473 55.368 22.665 1.00 28.23 ? 1807 HOH A O 1 HETATM 9283 O O . HOH I 8 . ? 9.810 53.879 22.101 1.00 39.72 ? 1808 HOH A O 1 HETATM 9284 O O . HOH I 8 . ? 10.921 51.613 21.582 1.00 22.51 ? 1809 HOH A O 1 HETATM 9285 O O . HOH I 8 . ? 13.541 51.559 21.810 1.00 18.21 ? 1810 HOH A O 1 HETATM 9286 O O . HOH I 8 . ? 14.408 49.836 19.919 1.00 16.85 ? 1811 HOH A O 1 HETATM 9287 O O . HOH I 8 . ? 12.652 49.556 17.891 1.00 20.22 ? 1812 HOH A O 1 HETATM 9288 O O . HOH I 8 . ? 11.656 46.947 17.962 1.00 22.58 ? 1813 HOH A O 1 HETATM 9289 O O . HOH I 8 . ? 10.971 46.967 21.119 1.00 42.26 ? 1814 HOH A O 1 HETATM 9290 O O . HOH I 8 . ? 8.690 48.542 19.801 1.00 40.21 ? 1815 HOH A O 1 HETATM 9291 O O . HOH I 8 . ? 10.347 50.867 18.914 1.00 23.48 ? 1816 HOH A O 1 HETATM 9292 O O . HOH I 8 . ? 9.465 52.565 16.953 1.00 20.89 ? 1817 HOH A O 1 HETATM 9293 O O . HOH I 8 . ? 7.651 54.630 17.439 1.00 36.01 ? 1818 HOH A O 1 HETATM 9294 O O . HOH I 8 . ? 8.781 56.903 16.444 1.00 42.57 ? 1819 HOH A O 1 HETATM 9295 O O . HOH I 8 . ? 8.371 55.538 20.107 1.00 48.51 ? 1820 HOH A O 1 HETATM 9296 O O . HOH I 8 . ? 6.846 52.300 16.028 1.00 44.44 ? 1821 HOH A O 1 HETATM 9297 O O . HOH I 8 . ? 7.704 50.781 12.676 1.00 50.28 ? 1822 HOH A O 1 HETATM 9298 O O . HOH I 8 . ? 8.139 48.158 12.022 1.00 25.72 ? 1823 HOH A O 1 HETATM 9299 O O . HOH I 8 . ? 5.983 47.204 13.791 1.00 46.15 ? 1824 HOH A O 1 HETATM 9300 O O . HOH I 8 . ? 6.291 46.640 16.119 1.00 35.69 ? 1825 HOH A O 1 HETATM 9301 O O . HOH I 8 . ? 8.662 44.667 13.418 1.00 29.60 ? 1826 HOH A O 1 HETATM 9302 O O . HOH I 8 . ? 10.366 41.703 12.178 1.00 39.97 ? 1827 HOH A O 1 HETATM 9303 O O . HOH I 8 . ? 12.912 42.575 12.718 1.00 18.65 ? 1828 HOH A O 1 HETATM 9304 O O . HOH I 8 . ? 14.525 40.257 12.810 1.00 43.54 ? 1829 HOH A O 1 HETATM 9305 O O . HOH I 8 . ? 10.913 38.335 11.983 1.00 49.78 ? 1830 HOH A O 1 HETATM 9306 O O . HOH I 8 . ? 9.563 39.840 19.379 1.00 42.04 ? 1831 HOH A O 1 HETATM 9307 O O . HOH I 8 . ? 12.062 41.510 19.919 1.00 31.70 ? 1832 HOH A O 1 HETATM 9308 O O . HOH I 8 . ? 13.140 40.239 22.382 1.00 40.82 ? 1833 HOH A O 1 HETATM 9309 O O . HOH I 8 . ? 13.148 43.614 22.760 1.00 35.00 ? 1834 HOH A O 1 HETATM 9310 O O . HOH I 8 . ? 16.646 49.135 24.163 1.00 14.74 ? 1835 HOH A O 1 HETATM 9311 O O . HOH I 8 . ? 14.286 50.526 24.357 1.00 22.73 ? 1836 HOH A O 1 HETATM 9312 O O . HOH I 8 . ? 10.454 55.832 26.436 1.00 37.47 ? 1837 HOH A O 1 HETATM 9313 O O . HOH I 8 . ? 12.871 61.086 30.368 1.00 35.87 ? 1838 HOH A O 1 HETATM 9314 O O . HOH I 8 . ? 14.363 63.282 30.285 1.00 38.37 ? 1839 HOH A O 1 HETATM 9315 O O . HOH I 8 . ? 51.362 98.757 -32.194 1.00 43.03 ? 1840 HOH A O 1 HETATM 9316 O O . HOH I 8 . ? 18.152 60.701 24.509 1.00 18.19 ? 1841 HOH A O 1 HETATM 9317 O O . HOH I 8 . ? 28.037 61.095 19.502 1.00 11.63 ? 1842 HOH A O 1 HETATM 9318 O O . HOH I 8 . ? 28.951 62.578 13.829 1.00 54.39 ? 1843 HOH A O 1 HETATM 9319 O O . HOH I 8 . ? 29.354 65.680 15.612 1.00 26.07 ? 1844 HOH A O 1 HETATM 9320 O O . HOH I 8 . ? 31.014 68.146 13.789 1.00 24.83 ? 1845 HOH A O 1 HETATM 9321 O O . HOH I 8 . ? 31.941 71.085 13.413 1.00 27.34 ? 1846 HOH A O 1 HETATM 9322 O O . HOH I 8 . ? 29.877 72.161 12.260 1.00 21.14 ? 1847 HOH A O 1 HETATM 9323 O O . HOH I 8 . ? 29.779 75.605 10.833 1.00 25.84 ? 1848 HOH A O 1 HETATM 9324 O O . HOH I 8 . ? 30.291 77.991 11.637 1.00 43.72 ? 1849 HOH A O 1 HETATM 9325 O O . HOH I 8 . ? 34.776 77.534 12.398 1.00 27.63 ? 1850 HOH A O 1 HETATM 9326 O O . HOH I 8 . ? 35.237 76.310 14.887 1.00 45.27 ? 1851 HOH A O 1 HETATM 9327 O O . HOH I 8 . ? 35.715 73.809 15.097 1.00 34.68 ? 1852 HOH A O 1 HETATM 9328 O O . HOH I 8 . ? 34.779 70.318 12.975 1.00 17.76 ? 1853 HOH A O 1 HETATM 9329 O O . HOH I 8 . ? 34.377 67.565 12.237 1.00 14.20 ? 1854 HOH A O 1 HETATM 9330 O O . HOH I 8 . ? 38.776 62.442 8.414 1.00 9.92 ? 1855 HOH A O 1 HETATM 9331 O O . HOH I 8 . ? 40.363 62.812 6.108 1.00 8.59 ? 1856 HOH A O 1 HETATM 9332 O O . HOH I 8 . ? 43.009 56.866 6.132 1.00 10.68 ? 1857 HOH A O 1 HETATM 9333 O O . HOH I 8 . ? 40.185 56.287 5.776 1.00 11.76 ? 1858 HOH A O 1 HETATM 9334 O O . HOH I 8 . ? 39.693 55.739 3.051 1.00 13.21 ? 1859 HOH A O 1 HETATM 9335 O O A HOH I 8 . ? 42.744 56.517 2.766 0.50 8.55 ? 1860 HOH A O 1 HETATM 9336 O O B HOH I 8 . ? 42.069 55.458 1.543 0.50 16.72 ? 1860 HOH A O 1 HETATM 9337 O O . HOH I 8 . ? 38.843 53.070 2.212 1.00 25.50 ? 1861 HOH A O 1 HETATM 9338 O O . HOH I 8 . ? 36.777 51.643 3.750 1.00 12.24 ? 1862 HOH A O 1 HETATM 9339 O O . HOH I 8 . ? 35.984 53.089 1.337 1.00 11.53 ? 1863 HOH A O 1 HETATM 9340 O O . HOH I 8 . ? 34.296 52.419 -0.943 1.00 8.58 ? 1864 HOH A O 1 HETATM 9341 O O . HOH I 8 . ? 37.573 57.054 1.770 1.00 9.35 ? 1865 HOH A O 1 HETATM 9342 O O . HOH I 8 . ? 32.613 60.152 -1.833 1.00 8.30 ? 1866 HOH A O 1 HETATM 9343 O O . HOH I 8 . ? 33.145 62.757 0.089 1.00 7.05 ? 1867 HOH A O 1 HETATM 9344 O O . HOH I 8 . ? 30.983 57.262 4.506 1.00 26.07 ? 1868 HOH A O 1 HETATM 9345 O O . HOH I 8 . ? 24.421 55.703 -1.725 1.00 12.40 ? 1869 HOH A O 1 HETATM 9346 O O . HOH I 8 . ? 23.354 53.963 -3.582 1.00 13.23 ? 1870 HOH A O 1 HETATM 9347 O O A HOH I 8 . ? 24.238 53.224 -6.220 0.50 9.22 ? 1871 HOH A O 1 HETATM 9348 O O B HOH I 8 . ? 23.979 52.327 -5.271 0.50 14.14 ? 1871 HOH A O 1 HETATM 9349 O O . HOH I 8 . ? 23.170 54.464 -8.593 1.00 34.87 ? 1872 HOH A O 1 HETATM 9350 O O . HOH I 8 . ? 22.978 51.799 -8.535 1.00 15.84 ? 1873 HOH A O 1 HETATM 9351 O O . HOH I 8 . ? 25.574 51.264 -9.384 1.00 12.29 ? 1874 HOH A O 1 HETATM 9352 O O . HOH I 8 . ? 26.275 48.924 -10.883 1.00 10.12 ? 1875 HOH A O 1 HETATM 9353 O O . HOH I 8 . ? 26.132 49.609 -13.609 1.00 9.13 ? 1876 HOH A O 1 HETATM 9354 O O . HOH I 8 . ? 24.749 52.961 -11.686 1.00 9.15 ? 1877 HOH A O 1 HETATM 9355 O O . HOH I 8 . ? 22.358 54.418 -11.956 1.00 10.03 ? 1878 HOH A O 1 HETATM 9356 O O . HOH I 8 . ? 19.678 53.529 -11.744 1.00 11.28 ? 1879 HOH A O 1 HETATM 9357 O O . HOH I 8 . ? 18.621 51.071 -12.382 1.00 12.27 ? 1880 HOH A O 1 HETATM 9358 O O . HOH I 8 . ? 19.968 46.803 -14.232 1.00 18.02 ? 1881 HOH A O 1 HETATM 9359 O O . HOH I 8 . ? 17.519 45.618 -13.967 1.00 32.96 ? 1882 HOH A O 1 HETATM 9360 O O . HOH I 8 . ? 15.976 44.948 -11.665 1.00 38.85 ? 1883 HOH A O 1 HETATM 9361 O O . HOH I 8 . ? 13.452 45.802 -12.126 1.00 37.71 ? 1884 HOH A O 1 HETATM 9362 O O . HOH I 8 . ? 19.720 42.412 -14.855 1.00 38.63 ? 1885 HOH A O 1 HETATM 9363 O O . HOH I 8 . ? 20.090 39.762 -15.107 1.00 41.33 ? 1886 HOH A O 1 HETATM 9364 O O . HOH I 8 . ? 20.112 39.821 -12.499 1.00 41.30 ? 1887 HOH A O 1 HETATM 9365 O O . HOH I 8 . ? 22.219 40.756 -11.195 1.00 19.72 ? 1888 HOH A O 1 HETATM 9366 O O . HOH I 8 . ? 21.889 40.388 -8.655 1.00 27.28 ? 1889 HOH A O 1 HETATM 9367 O O . HOH I 8 . ? 20.744 42.655 -7.375 1.00 17.87 ? 1890 HOH A O 1 HETATM 9368 O O . HOH I 8 . ? 19.767 41.594 -4.933 1.00 24.43 ? 1891 HOH A O 1 HETATM 9369 O O . HOH I 8 . ? 19.138 42.459 -2.447 1.00 25.71 ? 1892 HOH A O 1 HETATM 9370 O O . HOH I 8 . ? 16.613 43.030 -2.184 1.00 28.46 ? 1893 HOH A O 1 HETATM 9371 O O . HOH I 8 . ? 15.285 40.447 -2.561 1.00 47.14 ? 1894 HOH A O 1 HETATM 9372 O O . HOH I 8 . ? 18.424 39.400 -2.452 1.00 36.89 ? 1895 HOH A O 1 HETATM 9373 O O . HOH I 8 . ? 17.896 38.060 -0.165 1.00 42.78 ? 1896 HOH A O 1 HETATM 9374 O O . HOH I 8 . ? 19.734 37.142 1.633 1.00 43.82 ? 1897 HOH A O 1 HETATM 9375 O O . HOH I 8 . ? 21.992 36.940 0.322 1.00 25.32 ? 1898 HOH A O 1 HETATM 9376 O O . HOH I 8 . ? 22.913 34.994 -1.091 1.00 49.75 ? 1899 HOH A O 1 HETATM 9377 O O . HOH I 8 . ? 24.624 34.516 0.731 1.00 43.61 ? 1900 HOH A O 1 HETATM 9378 O O . HOH I 8 . ? 22.397 33.548 1.887 1.00 39.85 ? 1901 HOH A O 1 HETATM 9379 O O . HOH I 8 . ? 24.770 33.062 6.494 1.00 25.06 ? 1902 HOH A O 1 HETATM 9380 O O . HOH I 8 . ? 24.459 33.159 9.566 1.00 29.26 ? 1903 HOH A O 1 HETATM 9381 O O . HOH I 8 . ? 26.291 40.113 8.015 1.00 10.88 ? 1904 HOH A O 1 HETATM 9382 O O . HOH I 8 . ? 25.891 39.778 5.273 1.00 10.51 ? 1905 HOH A O 1 HETATM 9383 O O . HOH I 8 . ? 24.052 41.995 6.978 1.00 11.25 ? 1906 HOH A O 1 HETATM 9384 O O . HOH I 8 . ? 28.193 39.750 11.352 1.00 12.89 ? 1907 HOH A O 1 HETATM 9385 O O . HOH I 8 . ? 34.739 36.454 3.560 1.00 36.38 ? 1908 HOH A O 1 HETATM 9386 O O . HOH I 8 . ? 37.167 37.596 2.861 1.00 32.25 ? 1909 HOH A O 1 HETATM 9387 O O . HOH I 8 . ? 38.326 40.121 1.815 1.00 11.99 ? 1910 HOH A O 1 HETATM 9388 O O . HOH I 8 . ? 40.021 39.713 -0.305 1.00 23.75 ? 1911 HOH A O 1 HETATM 9389 O O . HOH I 8 . ? 41.966 40.657 0.591 1.00 41.51 ? 1912 HOH A O 1 HETATM 9390 O O . HOH I 8 . ? 42.644 39.562 -1.348 1.00 26.41 ? 1913 HOH A O 1 HETATM 9391 O O . HOH I 8 . ? 44.534 41.861 -0.488 1.00 14.62 ? 1914 HOH A O 1 HETATM 9392 O O . HOH I 8 . ? 46.101 39.860 0.035 1.00 31.81 ? 1915 HOH A O 1 HETATM 9393 O O . HOH I 8 . ? 49.049 39.067 -3.122 1.00 45.37 ? 1916 HOH A O 1 HETATM 9394 O O . HOH I 8 . ? 52.433 36.649 -3.789 1.00 40.31 ? 1917 HOH A O 1 HETATM 9395 O O . HOH I 8 . ? 55.625 34.517 -4.846 1.00 38.35 ? 1918 HOH A O 1 HETATM 9396 O O . HOH I 8 . ? 58.161 34.746 -6.068 1.00 37.98 ? 1919 HOH A O 1 HETATM 9397 O O . HOH I 8 . ? 59.248 39.822 -4.182 1.00 43.93 ? 1920 HOH A O 1 HETATM 9398 O O A HOH I 8 . ? 63.139 45.727 -3.251 0.50 36.24 ? 1921 HOH A O 1 HETATM 9399 O O B HOH I 8 . ? 61.261 45.256 -3.770 0.50 22.39 ? 1921 HOH A O 1 HETATM 9400 O O . HOH I 8 . ? 65.852 45.690 -3.118 1.00 30.24 ? 1922 HOH A O 1 HETATM 9401 O O . HOH I 8 . ? 67.521 46.671 -1.333 1.00 26.42 ? 1923 HOH A O 1 HETATM 9402 O O . HOH I 8 . ? 65.485 46.307 0.554 1.00 53.26 ? 1924 HOH A O 1 HETATM 9403 O O . HOH I 8 . ? 62.882 44.762 -0.556 1.00 45.84 ? 1925 HOH A O 1 HETATM 9404 O O . HOH I 8 . ? 60.591 46.003 0.698 1.00 38.11 ? 1926 HOH A O 1 HETATM 9405 O O . HOH I 8 . ? 58.969 46.381 -1.450 1.00 22.39 ? 1927 HOH A O 1 HETATM 9406 O O . HOH I 8 . ? 57.984 42.248 1.600 1.00 22.39 ? 1928 HOH A O 1 HETATM 9407 O O . HOH I 8 . ? 59.594 45.096 4.883 1.00 44.32 ? 1929 HOH A O 1 HETATM 9408 O O . HOH I 8 . ? 54.234 46.026 4.883 1.00 40.44 ? 1930 HOH A O 1 HETATM 9409 O O . HOH I 8 . ? 54.146 46.305 8.038 1.00 36.85 ? 1931 HOH A O 1 HETATM 9410 O O . HOH I 8 . ? 52.848 43.989 7.588 1.00 31.97 ? 1932 HOH A O 1 HETATM 9411 O O . HOH I 8 . ? 51.337 45.372 10.048 1.00 31.53 ? 1933 HOH A O 1 HETATM 9412 O O . HOH I 8 . ? 53.722 45.028 12.769 1.00 50.14 ? 1934 HOH A O 1 HETATM 9413 O O . HOH I 8 . ? 52.198 50.649 6.379 1.00 11.19 ? 1935 HOH A O 1 HETATM 9414 O O . HOH I 8 . ? 56.184 53.427 -0.635 1.00 7.88 ? 1936 HOH A O 1 HETATM 9415 O O . HOH I 8 . ? 52.235 54.116 -4.847 1.00 8.77 ? 1937 HOH A O 1 HETATM 9416 O O . HOH I 8 . ? 51.484 56.685 -5.604 1.00 9.42 ? 1938 HOH A O 1 HETATM 9417 O O . HOH I 8 . ? 49.842 57.645 -7.585 1.00 11.02 ? 1939 HOH A O 1 HETATM 9418 O O . HOH I 8 . ? 50.905 59.927 -8.949 1.00 12.54 ? 1940 HOH A O 1 HETATM 9419 O O . HOH I 8 . ? 49.606 62.310 -8.648 1.00 10.96 ? 1941 HOH A O 1 HETATM 9420 O O . HOH I 8 . ? 50.060 59.538 -11.542 1.00 10.97 ? 1942 HOH A O 1 HETATM 9421 O O . HOH I 8 . ? 53.714 59.852 -9.376 1.00 12.20 ? 1943 HOH A O 1 HETATM 9422 O O . HOH I 8 . ? 55.665 59.361 -11.453 1.00 9.14 ? 1944 HOH A O 1 HETATM 9423 O O . HOH I 8 . ? 61.086 59.683 -8.209 1.00 8.94 ? 1945 HOH A O 1 HETATM 9424 O O . HOH I 8 . ? 59.580 60.663 -6.169 1.00 14.01 ? 1946 HOH A O 1 HETATM 9425 O O . HOH I 8 . ? 64.929 59.333 -3.537 1.00 14.10 ? 1947 HOH A O 1 HETATM 9426 O O . HOH I 8 . ? 68.877 58.290 -5.006 1.00 14.73 ? 1948 HOH A O 1 HETATM 9427 O O . HOH I 8 . ? 73.879 61.190 -6.215 1.00 44.96 ? 1949 HOH A O 1 HETATM 9428 O O . HOH I 8 . ? 73.090 65.029 -7.758 1.00 20.26 ? 1950 HOH A O 1 HETATM 9429 O O . HOH I 8 . ? 73.084 66.638 -10.050 1.00 22.76 ? 1951 HOH A O 1 HETATM 9430 O O . HOH I 8 . ? 75.658 67.202 -9.549 1.00 35.18 ? 1952 HOH A O 1 HETATM 9431 O O . HOH I 8 . ? 70.116 69.927 -12.583 1.00 13.85 ? 1953 HOH A O 1 HETATM 9432 O O . HOH I 8 . ? 66.583 62.633 -12.993 1.00 19.16 ? 1954 HOH A O 1 HETATM 9433 O O . HOH I 8 . ? 70.029 53.689 -10.074 1.00 37.66 ? 1955 HOH A O 1 HETATM 9434 O O . HOH I 8 . ? 70.706 52.157 -12.534 1.00 23.06 ? 1956 HOH A O 1 HETATM 9435 O O . HOH I 8 . ? 63.854 50.176 -13.959 1.00 13.69 ? 1957 HOH A O 1 HETATM 9436 O O . HOH I 8 . ? 63.555 44.629 -6.671 1.00 16.92 ? 1958 HOH A O 1 HETATM 9437 O O . HOH I 8 . ? 64.366 43.303 -2.611 1.00 42.92 ? 1959 HOH A O 1 HETATM 9438 O O . HOH I 8 . ? 68.251 49.382 -0.934 1.00 24.38 ? 1960 HOH A O 1 HETATM 9439 O O . HOH I 8 . ? 66.044 50.530 0.324 1.00 39.95 ? 1961 HOH A O 1 HETATM 9440 O O . HOH I 8 . ? 67.408 52.786 1.376 1.00 40.82 ? 1962 HOH A O 1 HETATM 9441 O O . HOH I 8 . ? 67.133 55.401 0.954 1.00 19.93 ? 1963 HOH A O 1 HETATM 9442 O O . HOH I 8 . ? 69.951 55.317 1.646 1.00 45.17 ? 1964 HOH A O 1 HETATM 9443 O O . HOH I 8 . ? 63.569 52.042 -0.268 1.00 28.77 ? 1965 HOH A O 1 HETATM 9444 O O . HOH I 8 . ? 61.644 59.483 5.294 1.00 48.58 ? 1966 HOH A O 1 HETATM 9445 O O . HOH I 8 . ? 58.667 60.519 5.923 1.00 32.73 ? 1967 HOH A O 1 HETATM 9446 O O . HOH I 8 . ? 57.526 58.530 5.444 1.00 21.19 ? 1968 HOH A O 1 HETATM 9447 O O . HOH I 8 . ? 55.322 59.119 3.870 1.00 15.01 ? 1969 HOH A O 1 HETATM 9448 O O . HOH I 8 . ? 56.997 61.063 1.617 1.00 15.72 ? 1970 HOH A O 1 HETATM 9449 O O . HOH I 8 . ? 52.817 58.910 -1.732 1.00 12.47 ? 1971 HOH A O 1 HETATM 9450 O O . HOH I 8 . ? 57.699 62.454 7.831 1.00 24.05 ? 1972 HOH A O 1 HETATM 9451 O O . HOH I 8 . ? 56.522 64.496 8.895 1.00 47.17 ? 1973 HOH A O 1 HETATM 9452 O O . HOH I 8 . ? 52.497 71.049 5.870 1.00 28.49 ? 1974 HOH A O 1 HETATM 9453 O O . HOH I 8 . ? 52.500 73.208 4.063 1.00 33.33 ? 1975 HOH A O 1 HETATM 9454 O O . HOH I 8 . ? 56.456 71.271 3.834 1.00 37.17 ? 1976 HOH A O 1 HETATM 9455 O O . HOH I 8 . ? 54.089 80.365 0.813 1.00 44.53 ? 1977 HOH A O 1 HETATM 9456 O O . HOH I 8 . ? 51.703 80.146 0.769 1.00 36.58 ? 1978 HOH A O 1 HETATM 9457 O O . HOH I 8 . ? 51.343 79.296 -1.739 1.00 21.66 ? 1979 HOH A O 1 HETATM 9458 O O . HOH I 8 . ? 50.345 81.214 -2.966 1.00 38.97 ? 1980 HOH A O 1 HETATM 9459 O O . HOH I 8 . ? 48.171 80.351 -4.221 1.00 38.20 ? 1981 HOH A O 1 HETATM 9460 O O . HOH I 8 . ? 41.103 81.829 -3.669 1.00 31.19 ? 1982 HOH A O 1 HETATM 9461 O O . HOH I 8 . ? 38.822 80.290 -3.225 1.00 33.41 ? 1983 HOH A O 1 HETATM 9462 O O . HOH I 8 . ? 37.679 80.507 -0.685 1.00 20.38 ? 1984 HOH A O 1 HETATM 9463 O O . HOH I 8 . ? 38.125 83.279 -1.113 1.00 30.31 ? 1985 HOH A O 1 HETATM 9464 O O . HOH I 8 . ? 37.267 83.658 -4.141 1.00 28.32 ? 1986 HOH A O 1 HETATM 9465 O O . HOH I 8 . ? 35.289 84.967 -0.695 1.00 35.87 ? 1987 HOH A O 1 HETATM 9466 O O . HOH I 8 . ? 32.852 84.316 0.393 1.00 28.76 ? 1988 HOH A O 1 HETATM 9467 O O . HOH I 8 . ? 31.323 81.686 0.609 1.00 17.65 ? 1989 HOH A O 1 HETATM 9468 O O . HOH I 8 . ? 29.862 83.080 2.473 1.00 20.67 ? 1990 HOH A O 1 HETATM 9469 O O . HOH I 8 . ? 27.489 82.356 3.303 1.00 31.24 ? 1991 HOH A O 1 HETATM 9470 O O . HOH I 8 . ? 24.711 84.027 2.403 1.00 31.90 ? 1992 HOH A O 1 HETATM 9471 O O . HOH I 8 . ? 58.974 77.989 0.515 1.00 40.48 ? 1993 HOH A O 1 HETATM 9472 O O . HOH I 8 . ? 55.550 78.543 2.258 1.00 51.30 ? 1994 HOH A O 1 HETATM 9473 O O . HOH I 8 . ? 18.194 84.429 -4.974 1.00 40.42 ? 1995 HOH A O 1 HETATM 9474 O O . HOH I 8 . ? 16.681 82.107 -5.101 1.00 31.90 ? 1996 HOH A O 1 HETATM 9475 O O . HOH I 8 . ? 17.229 80.674 -7.415 1.00 22.44 ? 1997 HOH A O 1 HETATM 9476 O O . HOH I 8 . ? 18.475 84.376 -8.353 1.00 49.39 ? 1998 HOH A O 1 HETATM 9477 O O . HOH I 8 . ? 21.008 83.868 -12.473 1.00 35.87 ? 1999 HOH A O 1 HETATM 9478 O O . HOH I 8 . ? 18.903 80.561 -11.747 1.00 31.83 ? 2000 HOH A O 1 HETATM 9479 O O . HOH I 8 . ? 15.511 76.998 -13.615 1.00 31.14 ? 2001 HOH A O 1 HETATM 9480 O O . HOH I 8 . ? 15.875 75.226 -11.719 1.00 19.38 ? 2002 HOH A O 1 HETATM 9481 O O . HOH I 8 . ? 12.334 75.100 -13.375 1.00 29.49 ? 2003 HOH A O 1 HETATM 9482 O O . HOH I 8 . ? 13.639 70.010 -9.574 1.00 26.13 ? 2004 HOH A O 1 HETATM 9483 O O . HOH I 8 . ? 14.117 68.219 -7.789 1.00 18.37 ? 2005 HOH A O 1 HETATM 9484 O O . HOH I 8 . ? 12.712 66.331 -9.624 1.00 19.56 ? 2006 HOH A O 1 HETATM 9485 O O . HOH I 8 . ? 12.379 68.407 -11.462 1.00 20.91 ? 2007 HOH A O 1 HETATM 9486 O O . HOH I 8 . ? 12.771 67.032 -13.635 1.00 20.20 ? 2008 HOH A O 1 HETATM 9487 O O . HOH I 8 . ? 10.602 64.619 -10.300 1.00 34.83 ? 2009 HOH A O 1 HETATM 9488 O O . HOH I 8 . ? 11.612 70.823 -7.693 1.00 33.91 ? 2010 HOH A O 1 HETATM 9489 O O . HOH I 8 . ? 9.742 73.275 -2.584 1.00 45.16 ? 2011 HOH A O 1 HETATM 9490 O O . HOH I 8 . ? 10.667 77.233 -5.056 1.00 35.80 ? 2012 HOH A O 1 HETATM 9491 O O . HOH I 8 . ? 8.005 81.385 -4.350 1.00 34.40 ? 2013 HOH A O 1 HETATM 9492 O O . HOH I 8 . ? 12.035 81.871 0.995 1.00 38.46 ? 2014 HOH A O 1 HETATM 9493 O O . HOH I 8 . ? 16.119 80.225 -1.072 1.00 50.48 ? 2015 HOH A O 1 HETATM 9494 O O . HOH I 8 . ? 21.368 78.524 -1.399 1.00 16.41 ? 2016 HOH A O 1 HETATM 9495 O O . HOH I 8 . ? 24.068 82.965 -3.889 1.00 40.00 ? 2017 HOH A O 1 HETATM 9496 O O . HOH I 8 . ? 26.777 87.831 -3.889 1.00 41.16 ? 2018 HOH A O 1 HETATM 9497 O O . HOH I 8 . ? 23.906 89.580 -6.660 1.00 45.35 ? 2019 HOH A O 1 HETATM 9498 O O . HOH I 8 . ? 22.173 87.838 -7.691 1.00 47.10 ? 2020 HOH A O 1 HETATM 9499 O O . HOH I 8 . ? 25.034 91.888 -8.218 1.00 55.13 ? 2021 HOH A O 1 HETATM 9500 O O . HOH I 8 . ? 27.341 88.577 -12.406 1.00 31.78 ? 2022 HOH A O 1 HETATM 9501 O O . HOH I 8 . ? 29.477 89.997 -12.352 1.00 52.72 ? 2023 HOH A O 1 HETATM 9502 O O . HOH I 8 . ? 34.177 87.115 -10.471 1.00 31.82 ? 2024 HOH A O 1 HETATM 9503 O O . HOH I 8 . ? 35.553 86.052 -8.064 1.00 31.33 ? 2025 HOH A O 1 HETATM 9504 O O . HOH I 8 . ? 35.633 88.451 -6.298 1.00 43.15 ? 2026 HOH A O 1 HETATM 9505 O O . HOH I 8 . ? 32.826 85.370 -5.616 1.00 17.79 ? 2027 HOH A O 1 HETATM 9506 O O . HOH I 8 . ? 31.555 87.638 -6.605 1.00 40.39 ? 2028 HOH A O 1 HETATM 9507 O O . HOH I 8 . ? 32.153 85.233 -8.516 1.00 18.34 ? 2029 HOH A O 1 HETATM 9508 O O . HOH I 8 . ? 33.559 83.599 -10.376 1.00 15.50 ? 2030 HOH A O 1 HETATM 9509 O O . HOH I 8 . ? 32.792 81.088 -11.690 1.00 10.39 ? 2031 HOH A O 1 HETATM 9510 O O . HOH I 8 . ? 34.545 79.166 -9.137 1.00 11.31 ? 2032 HOH A O 1 HETATM 9511 O O . HOH I 8 . ? 35.861 77.549 -7.330 1.00 12.21 ? 2033 HOH A O 1 HETATM 9512 O O . HOH I 8 . ? 36.336 79.248 -5.043 1.00 20.42 ? 2034 HOH A O 1 HETATM 9513 O O . HOH I 8 . ? 33.374 78.633 -5.136 1.00 11.79 ? 2035 HOH A O 1 HETATM 9514 O O . HOH I 8 . ? 31.393 76.766 -6.341 1.00 10.45 ? 2036 HOH A O 1 HETATM 9515 O O . HOH I 8 . ? 37.100 71.903 -4.544 1.00 7.98 ? 2037 HOH A O 1 HETATM 9516 O O . HOH I 8 . ? 37.897 73.322 -2.240 1.00 10.15 ? 2038 HOH A O 1 HETATM 9517 O O . HOH I 8 . ? 36.645 72.657 0.294 1.00 8.47 ? 2039 HOH A O 1 HETATM 9518 O O . HOH I 8 . ? 43.575 73.235 5.782 1.00 11.11 ? 2040 HOH A O 1 HETATM 9519 O O . HOH I 8 . ? 46.125 70.945 0.064 1.00 14.42 ? 2041 HOH A O 1 HETATM 9520 O O . HOH I 8 . ? 42.053 63.495 -7.153 1.00 6.45 ? 2042 HOH A O 1 HETATM 9521 O O . HOH I 8 . ? 39.300 64.822 -14.712 1.00 9.98 ? 2043 HOH A O 1 HETATM 9522 O O . HOH I 8 . ? 39.270 62.871 -19.114 1.00 7.77 ? 2044 HOH A O 1 HETATM 9523 O O . HOH I 8 . ? 39.698 58.890 -18.019 1.00 21.02 ? 2045 HOH A O 1 HETATM 9524 O O . HOH I 8 . ? 41.711 58.672 -15.996 1.00 13.60 ? 2046 HOH A O 1 HETATM 9525 O O . HOH I 8 . ? 44.558 58.772 -15.915 1.00 15.33 ? 2047 HOH A O 1 HETATM 9526 O O . HOH I 8 . ? 44.563 56.112 -15.345 1.00 16.80 ? 2048 HOH A O 1 HETATM 9527 O O . HOH I 8 . ? 47.335 55.776 -15.435 1.00 16.56 ? 2049 HOH A O 1 HETATM 9528 O O . HOH I 8 . ? 45.046 55.062 -18.053 1.00 25.68 ? 2050 HOH A O 1 HETATM 9529 O O . HOH I 8 . ? 46.011 52.761 -19.075 1.00 16.49 ? 2051 HOH A O 1 HETATM 9530 O O . HOH I 8 . ? 46.900 53.827 -21.450 1.00 24.99 ? 2052 HOH A O 1 HETATM 9531 O O . HOH I 8 . ? 48.766 54.910 -22.713 1.00 22.45 ? 2053 HOH A O 1 HETATM 9532 O O . HOH I 8 . ? 51.320 53.323 -23.893 1.00 12.85 ? 2054 HOH A O 1 HETATM 9533 O O . HOH I 8 . ? 51.138 52.807 -28.526 1.00 20.45 ? 2055 HOH A O 1 HETATM 9534 O O . HOH I 8 . ? 49.883 55.163 -29.014 1.00 19.15 ? 2056 HOH A O 1 HETATM 9535 O O . HOH I 8 . ? 52.161 56.496 -30.205 1.00 25.27 ? 2057 HOH A O 1 HETATM 9536 O O . HOH I 8 . ? 53.156 55.078 -31.890 1.00 32.21 ? 2058 HOH A O 1 HETATM 9537 O O . HOH I 8 . ? 53.378 53.411 -30.007 1.00 26.85 ? 2059 HOH A O 1 HETATM 9538 O O . HOH I 8 . ? 56.451 50.024 -30.053 1.00 33.74 ? 2060 HOH A O 1 HETATM 9539 O O . HOH I 8 . ? 49.828 47.048 -30.413 1.00 39.32 ? 2061 HOH A O 1 HETATM 9540 O O A HOH I 8 . ? 48.983 51.016 -29.742 0.50 22.15 ? 2062 HOH A O 1 HETATM 9541 O O B HOH I 8 . ? 48.699 49.840 -29.205 0.50 16.37 ? 2062 HOH A O 1 HETATM 9542 O O . HOH I 8 . ? 47.823 49.574 -31.368 1.00 40.71 ? 2063 HOH A O 1 HETATM 9543 O O . HOH I 8 . ? 47.840 53.580 -31.141 1.00 50.97 ? 2064 HOH A O 1 HETATM 9544 O O . HOH I 8 . ? 45.649 56.218 -32.538 1.00 45.36 ? 2065 HOH A O 1 HETATM 9545 O O . HOH I 8 . ? 47.640 57.872 -32.166 1.00 42.77 ? 2066 HOH A O 1 HETATM 9546 O O . HOH I 8 . ? 50.125 58.414 -30.743 1.00 40.42 ? 2067 HOH A O 1 HETATM 9547 O O . HOH I 8 . ? 49.115 59.301 -28.558 1.00 31.69 ? 2068 HOH A O 1 HETATM 9548 O O . HOH I 8 . ? 48.212 61.743 -28.361 1.00 32.88 ? 2069 HOH A O 1 HETATM 9549 O O . HOH I 8 . ? 46.061 61.379 -29.879 1.00 40.87 ? 2070 HOH A O 1 HETATM 9550 O O . HOH I 8 . ? 43.697 62.703 -28.368 1.00 21.77 ? 2071 HOH A O 1 HETATM 9551 O O . HOH I 8 . ? 41.750 61.195 -29.565 1.00 18.58 ? 2072 HOH A O 1 HETATM 9552 O O . HOH I 8 . ? 42.860 59.350 -31.392 1.00 25.55 ? 2073 HOH A O 1 HETATM 9553 O O . HOH I 8 . ? 42.929 56.690 -31.461 1.00 25.77 ? 2074 HOH A O 1 HETATM 9554 O O . HOH I 8 . ? 40.808 55.830 -33.258 1.00 28.44 ? 2075 HOH A O 1 HETATM 9555 O O . HOH I 8 . ? 38.585 55.103 -31.592 1.00 16.31 ? 2076 HOH A O 1 HETATM 9556 O O . HOH I 8 . ? 37.209 52.656 -32.288 1.00 30.05 ? 2077 HOH A O 1 HETATM 9557 O O . HOH I 8 . ? 38.571 51.394 -29.797 1.00 26.03 ? 2078 HOH A O 1 HETATM 9558 O O . HOH I 8 . ? 43.822 54.845 -26.756 1.00 29.26 ? 2079 HOH A O 1 HETATM 9559 O O . HOH I 8 . ? 46.909 55.765 -25.471 1.00 18.32 ? 2080 HOH A O 1 HETATM 9560 O O . HOH I 8 . ? 47.875 59.361 -25.638 1.00 15.29 ? 2081 HOH A O 1 HETATM 9561 O O . HOH I 8 . ? 47.185 62.093 -25.580 1.00 23.14 ? 2082 HOH A O 1 HETATM 9562 O O . HOH I 8 . ? 48.697 64.756 -25.948 1.00 65.88 ? 2083 HOH A O 1 HETATM 9563 O O . HOH I 8 . ? 48.398 64.476 -28.574 1.00 34.05 ? 2084 HOH A O 1 HETATM 9564 O O . HOH I 8 . ? 47.507 68.222 -30.807 1.00 17.67 ? 2085 HOH A O 1 HETATM 9565 O O . HOH I 8 . ? 47.375 70.077 -28.596 1.00 27.09 ? 2086 HOH A O 1 HETATM 9566 O O . HOH I 8 . ? 45.948 68.134 -26.945 1.00 16.58 ? 2087 HOH A O 1 HETATM 9567 O O . HOH I 8 . ? 47.201 67.839 -24.566 1.00 23.66 ? 2088 HOH A O 1 HETATM 9568 O O . HOH I 8 . ? 47.176 70.754 -24.740 1.00 35.68 ? 2089 HOH A O 1 HETATM 9569 O O . HOH I 8 . ? 45.145 71.974 -25.805 1.00 40.19 ? 2090 HOH A O 1 HETATM 9570 O O . HOH I 8 . ? 43.542 68.306 -25.278 1.00 14.05 ? 2091 HOH A O 1 HETATM 9571 O O . HOH I 8 . ? 43.531 66.784 -32.283 1.00 26.53 ? 2092 HOH A O 1 HETATM 9572 O O . HOH I 8 . ? 41.281 68.266 -32.591 1.00 18.46 ? 2093 HOH A O 1 HETATM 9573 O O . HOH I 8 . ? 39.451 69.072 -35.407 1.00 17.00 ? 2094 HOH A O 1 HETATM 9574 O O . HOH I 8 . ? 38.702 69.157 -38.163 1.00 18.99 ? 2095 HOH A O 1 HETATM 9575 O O . HOH I 8 . ? 43.109 65.441 -39.344 1.00 33.61 ? 2096 HOH A O 1 HETATM 9576 O O . HOH I 8 . ? 45.135 66.498 -34.571 1.00 40.36 ? 2097 HOH A O 1 HETATM 9577 O O . HOH I 8 . ? 45.209 63.866 -34.511 1.00 46.67 ? 2098 HOH A O 1 HETATM 9578 O O . HOH I 8 . ? 43.375 63.804 -32.495 1.00 30.75 ? 2099 HOH A O 1 HETATM 9579 O O . HOH I 8 . ? 41.055 62.892 -31.730 1.00 23.11 ? 2100 HOH A O 1 HETATM 9580 O O . HOH I 8 . ? 45.158 57.335 -34.884 1.00 50.78 ? 2101 HOH A O 1 HETATM 9581 O O . HOH I 8 . ? 50.545 61.237 -30.942 1.00 22.72 ? 2102 HOH A O 1 HETATM 9582 O O . HOH I 8 . ? 53.061 59.298 -32.491 1.00 43.42 ? 2103 HOH A O 1 HETATM 9583 O O . HOH I 8 . ? 55.210 58.854 -34.175 1.00 35.17 ? 2104 HOH A O 1 HETATM 9584 O O . HOH I 8 . ? 56.212 65.187 -36.085 1.00 24.81 ? 2105 HOH A O 1 HETATM 9585 O O . HOH I 8 . ? 56.932 67.629 -35.465 1.00 21.26 ? 2106 HOH A O 1 HETATM 9586 O O . HOH I 8 . ? 57.754 68.359 -37.860 1.00 39.21 ? 2107 HOH A O 1 HETATM 9587 O O . HOH I 8 . ? 55.491 69.107 -37.703 1.00 27.04 ? 2108 HOH A O 1 HETATM 9588 O O . HOH I 8 . ? 56.917 70.006 -39.739 1.00 31.21 ? 2109 HOH A O 1 HETATM 9589 O O . HOH I 8 . ? 53.995 71.219 -36.862 1.00 13.41 ? 2110 HOH A O 1 HETATM 9590 O O . HOH I 8 . ? 51.753 70.086 -38.138 1.00 28.87 ? 2111 HOH A O 1 HETATM 9591 O O . HOH I 8 . ? 49.079 69.106 -36.799 1.00 29.76 ? 2112 HOH A O 1 HETATM 9592 O O . HOH I 8 . ? 46.652 70.264 -36.675 1.00 17.61 ? 2113 HOH A O 1 HETATM 9593 O O . HOH I 8 . ? 46.267 70.269 -39.933 1.00 37.29 ? 2114 HOH A O 1 HETATM 9594 O O . HOH I 8 . ? 46.621 69.716 -43.141 1.00 58.75 ? 2115 HOH A O 1 HETATM 9595 O O . HOH I 8 . ? 44.735 72.178 -44.389 1.00 36.79 ? 2116 HOH A O 1 HETATM 9596 O O . HOH I 8 . ? 43.880 72.520 -41.919 1.00 21.26 ? 2117 HOH A O 1 HETATM 9597 O O . HOH I 8 . ? 42.243 74.664 -41.408 1.00 26.26 ? 2118 HOH A O 1 HETATM 9598 O O . HOH I 8 . ? 39.805 75.539 -40.292 1.00 18.48 ? 2119 HOH A O 1 HETATM 9599 O O . HOH I 8 . ? 37.733 75.512 -42.275 1.00 22.68 ? 2120 HOH A O 1 HETATM 9600 O O . HOH I 8 . ? 35.859 77.315 -42.995 1.00 34.25 ? 2121 HOH A O 1 HETATM 9601 O O . HOH I 8 . ? 34.064 73.878 -43.755 1.00 44.72 ? 2122 HOH A O 1 HETATM 9602 O O . HOH I 8 . ? 28.113 68.147 -46.952 1.00 51.33 ? 2123 HOH A O 1 HETATM 9603 O O . HOH I 8 . ? 23.994 65.258 -43.625 1.00 35.75 ? 2124 HOH A O 1 HETATM 9604 O O . HOH I 8 . ? 21.919 63.154 -43.085 1.00 45.14 ? 2125 HOH A O 1 HETATM 9605 O O . HOH I 8 . ? 22.283 60.680 -43.867 1.00 33.84 ? 2126 HOH A O 1 HETATM 9606 O O . HOH I 8 . ? 24.024 58.497 -43.931 1.00 43.63 ? 2127 HOH A O 1 HETATM 9607 O O . HOH I 8 . ? 24.628 60.475 -45.930 1.00 47.30 ? 2128 HOH A O 1 HETATM 9608 O O . HOH I 8 . ? 25.960 57.205 -41.956 1.00 52.61 ? 2129 HOH A O 1 HETATM 9609 O O . HOH I 8 . ? 28.574 59.825 -39.056 1.00 31.11 ? 2130 HOH A O 1 HETATM 9610 O O . HOH I 8 . ? 29.149 62.223 -39.763 1.00 25.96 ? 2131 HOH A O 1 HETATM 9611 O O . HOH I 8 . ? 31.280 58.391 -40.326 1.00 39.19 ? 2132 HOH A O 1 HETATM 9612 O O . HOH I 8 . ? 33.324 57.019 -38.882 1.00 38.68 ? 2133 HOH A O 1 HETATM 9613 O O . HOH I 8 . ? 32.186 58.531 -28.453 1.00 13.41 ? 2134 HOH A O 1 HETATM 9614 O O . HOH I 8 . ? 34.136 56.257 -26.235 1.00 11.08 ? 2135 HOH A O 1 HETATM 9615 O O . HOH I 8 . ? 31.344 49.904 -23.968 1.00 12.19 ? 2136 HOH A O 1 HETATM 9616 O O . HOH I 8 . ? 28.728 49.643 -24.339 1.00 16.49 ? 2137 HOH A O 1 HETATM 9617 O O . HOH I 8 . ? 27.036 47.536 -23.838 1.00 32.51 ? 2138 HOH A O 1 HETATM 9618 O O . HOH I 8 . ? 27.566 48.426 -21.617 1.00 15.75 ? 2139 HOH A O 1 HETATM 9619 O O . HOH I 8 . ? 25.322 46.881 -20.913 1.00 23.61 ? 2140 HOH A O 1 HETATM 9620 O O . HOH I 8 . ? 21.481 46.751 -17.513 1.00 26.81 ? 2141 HOH A O 1 HETATM 9621 O O . HOH I 8 . ? 23.656 45.964 -15.846 1.00 19.55 ? 2142 HOH A O 1 HETATM 9622 O O . HOH I 8 . ? 22.571 45.420 -13.365 1.00 16.21 ? 2143 HOH A O 1 HETATM 9623 O O . HOH I 8 . ? 21.999 42.708 -13.179 1.00 22.42 ? 2144 HOH A O 1 HETATM 9624 O O . HOH I 8 . ? 24.274 42.026 -14.531 1.00 22.73 ? 2145 HOH A O 1 HETATM 9625 O O . HOH I 8 . ? 26.695 41.626 -13.157 1.00 12.82 ? 2146 HOH A O 1 HETATM 9626 O O . HOH I 8 . ? 28.835 42.774 -11.882 1.00 11.00 ? 2147 HOH A O 1 HETATM 9627 O O . HOH I 8 . ? 24.456 39.060 -11.396 1.00 23.27 ? 2148 HOH A O 1 HETATM 9628 O O . HOH I 8 . ? 23.798 37.320 -13.358 1.00 36.97 ? 2149 HOH A O 1 HETATM 9629 O O . HOH I 8 . ? 21.545 37.414 -12.040 1.00 49.71 ? 2150 HOH A O 1 HETATM 9630 O O . HOH I 8 . ? 22.761 36.890 -9.699 1.00 41.71 ? 2151 HOH A O 1 HETATM 9631 O O . HOH I 8 . ? 25.413 34.592 -7.149 1.00 42.57 ? 2152 HOH A O 1 HETATM 9632 O O . HOH I 8 . ? 28.074 35.370 -6.690 1.00 24.32 ? 2153 HOH A O 1 HETATM 9633 O O . HOH I 8 . ? 30.331 33.481 -6.153 1.00 39.45 ? 2154 HOH A O 1 HETATM 9634 O O . HOH I 8 . ? 32.084 34.408 -3.209 1.00 20.26 ? 2155 HOH A O 1 HETATM 9635 O O . HOH I 8 . ? 29.993 34.252 -1.505 1.00 27.70 ? 2156 HOH A O 1 HETATM 9636 O O . HOH I 8 . ? 27.130 33.956 -3.195 1.00 35.82 ? 2157 HOH A O 1 HETATM 9637 O O . HOH I 8 . ? 21.452 35.484 -5.228 1.00 33.68 ? 2158 HOH A O 1 HETATM 9638 O O . HOH I 8 . ? 20.325 37.551 -6.166 1.00 43.56 ? 2159 HOH A O 1 HETATM 9639 O O . HOH I 8 . ? 23.074 39.227 -15.500 1.00 27.99 ? 2160 HOH A O 1 HETATM 9640 O O . HOH I 8 . ? 23.593 37.688 -17.591 1.00 38.39 ? 2161 HOH A O 1 HETATM 9641 O O . HOH I 8 . ? 25.583 36.267 -15.307 1.00 34.63 ? 2162 HOH A O 1 HETATM 9642 O O . HOH I 8 . ? 29.413 35.041 -16.408 1.00 29.13 ? 2163 HOH A O 1 HETATM 9643 O O . HOH I 8 . ? 29.512 34.396 -19.200 1.00 45.22 ? 2164 HOH A O 1 HETATM 9644 O O . HOH I 8 . ? 27.632 36.450 -19.604 1.00 26.34 ? 2165 HOH A O 1 HETATM 9645 O O . HOH I 8 . ? 27.785 38.682 -22.501 1.00 29.34 ? 2166 HOH A O 1 HETATM 9646 O O . HOH I 8 . ? 27.271 39.750 -24.788 1.00 43.84 ? 2167 HOH A O 1 HETATM 9647 O O . HOH I 8 . ? 29.485 41.054 -25.538 1.00 20.46 ? 2168 HOH A O 1 HETATM 9648 O O . HOH I 8 . ? 30.277 39.059 -27.074 1.00 23.29 ? 2169 HOH A O 1 HETATM 9649 O O . HOH I 8 . ? 28.462 44.174 -29.589 1.00 32.71 ? 2170 HOH A O 1 HETATM 9650 O O . HOH I 8 . ? 26.427 44.240 -27.201 1.00 30.26 ? 2171 HOH A O 1 HETATM 9651 O O . HOH I 8 . ? 28.182 47.033 -31.436 1.00 29.54 ? 2172 HOH A O 1 HETATM 9652 O O . HOH I 8 . ? 35.607 45.162 -27.355 1.00 17.32 ? 2173 HOH A O 1 HETATM 9653 O O . HOH I 8 . ? 37.359 45.241 -25.360 1.00 24.37 ? 2174 HOH A O 1 HETATM 9654 O O . HOH I 8 . ? 39.819 45.287 -26.358 1.00 34.81 ? 2175 HOH A O 1 HETATM 9655 O O . HOH I 8 . ? 37.002 41.257 -24.494 1.00 28.94 ? 2176 HOH A O 1 HETATM 9656 O O . HOH I 8 . ? 35.811 41.692 -26.562 1.00 43.12 ? 2177 HOH A O 1 HETATM 9657 O O . HOH I 8 . ? 38.303 39.555 -26.555 1.00 47.00 ? 2178 HOH A O 1 HETATM 9658 O O . HOH I 8 . ? 38.695 42.208 -22.045 1.00 28.27 ? 2179 HOH A O 1 HETATM 9659 O O . HOH I 8 . ? 40.960 40.720 -21.405 1.00 27.43 ? 2180 HOH A O 1 HETATM 9660 O O . HOH I 8 . ? 41.612 41.149 -17.451 1.00 19.99 ? 2181 HOH A O 1 HETATM 9661 O O . HOH I 8 . ? 42.619 39.396 -15.723 1.00 28.09 ? 2182 HOH A O 1 HETATM 9662 O O . HOH I 8 . ? 40.887 42.200 -15.107 1.00 50.59 ? 2183 HOH A O 1 HETATM 9663 O O . HOH I 8 . ? 39.958 42.750 -12.650 1.00 47.35 ? 2184 HOH A O 1 HETATM 9664 O O . HOH I 8 . ? 42.212 40.404 -9.724 1.00 42.28 ? 2185 HOH A O 1 HETATM 9665 O O . HOH I 8 . ? 44.306 38.175 -8.714 1.00 54.23 ? 2186 HOH A O 1 HETATM 9666 O O . HOH I 8 . ? 43.246 38.507 -6.135 1.00 35.84 ? 2187 HOH A O 1 HETATM 9667 O O . HOH I 8 . ? 39.879 38.806 -3.364 1.00 22.19 ? 2188 HOH A O 1 HETATM 9668 O O . HOH I 8 . ? 36.289 36.310 -1.901 1.00 52.72 ? 2189 HOH A O 1 HETATM 9669 O O . HOH I 8 . ? 35.957 36.034 -4.446 1.00 19.24 ? 2190 HOH A O 1 HETATM 9670 O O . HOH I 8 . ? 35.779 33.559 -3.516 1.00 58.18 ? 2191 HOH A O 1 HETATM 9671 O O . HOH I 8 . ? 36.277 33.737 -6.135 1.00 44.37 ? 2192 HOH A O 1 HETATM 9672 O O . HOH I 8 . ? 33.233 36.645 -4.327 1.00 15.69 ? 2193 HOH A O 1 HETATM 9673 O O . HOH I 8 . ? 32.349 39.151 -4.843 1.00 11.10 ? 2194 HOH A O 1 HETATM 9674 O O . HOH I 8 . ? 30.387 34.772 -9.553 1.00 34.20 ? 2195 HOH A O 1 HETATM 9675 O O . HOH I 8 . ? 30.273 35.163 -12.368 1.00 22.10 ? 2196 HOH A O 1 HETATM 9676 O O . HOH I 8 . ? 32.738 32.399 -11.605 1.00 46.13 ? 2197 HOH A O 1 HETATM 9677 O O . HOH I 8 . ? 34.199 32.763 -13.683 1.00 47.61 ? 2198 HOH A O 1 HETATM 9678 O O . HOH I 8 . ? 36.945 34.945 -15.842 1.00 34.82 ? 2199 HOH A O 1 HETATM 9679 O O . HOH I 8 . ? 35.984 36.272 -18.133 1.00 49.59 ? 2200 HOH A O 1 HETATM 9680 O O . HOH I 8 . ? 37.869 35.154 -19.416 1.00 46.52 ? 2201 HOH A O 1 HETATM 9681 O O . HOH I 8 . ? 35.623 34.182 -21.348 1.00 46.20 ? 2202 HOH A O 1 HETATM 9682 O O . HOH I 8 . ? 36.341 35.333 -23.618 1.00 34.74 ? 2203 HOH A O 1 HETATM 9683 O O . HOH I 8 . ? 33.548 38.796 -19.449 1.00 30.12 ? 2204 HOH A O 1 HETATM 9684 O O . HOH I 8 . ? 32.994 41.041 -17.600 1.00 21.88 ? 2205 HOH A O 1 HETATM 9685 O O . HOH I 8 . ? 35.746 38.944 -16.035 1.00 31.13 ? 2206 HOH A O 1 HETATM 9686 O O . HOH I 8 . ? 39.444 38.260 -10.777 1.00 32.95 ? 2207 HOH A O 1 HETATM 9687 O O . HOH I 8 . ? 41.094 36.564 -12.660 1.00 49.81 ? 2208 HOH A O 1 HETATM 9688 O O . HOH I 8 . ? 41.436 44.755 -6.820 1.00 13.84 ? 2209 HOH A O 1 HETATM 9689 O O . HOH I 8 . ? 36.739 44.939 -5.404 1.00 10.03 ? 2210 HOH A O 1 HETATM 9690 O O . HOH I 8 . ? 31.738 47.036 -8.008 1.00 7.96 ? 2211 HOH A O 1 HETATM 9691 O O . HOH I 8 . ? 33.488 48.139 -10.079 1.00 8.97 ? 2212 HOH A O 1 HETATM 9692 O O . HOH I 8 . ? 34.999 48.231 -16.398 1.00 38.47 ? 2213 HOH A O 1 HETATM 9693 O O . HOH I 8 . ? 35.170 50.523 -17.503 1.00 13.34 ? 2214 HOH A O 1 HETATM 9694 O O . HOH I 8 . ? 37.594 51.481 -18.472 1.00 17.73 ? 2215 HOH A O 1 HETATM 9695 O O . HOH I 8 . ? 37.661 52.100 -21.039 1.00 11.91 ? 2216 HOH A O 1 HETATM 9696 O O . HOH I 8 . ? 39.694 53.914 -20.725 1.00 14.55 ? 2217 HOH A O 1 HETATM 9697 O O . HOH I 8 . ? 40.375 56.200 -19.199 1.00 25.13 ? 2218 HOH A O 1 HETATM 9698 O O . HOH I 8 . ? 42.402 54.757 -17.440 1.00 24.12 ? 2219 HOH A O 1 HETATM 9699 O O . HOH I 8 . ? 41.093 52.336 -16.902 1.00 12.11 ? 2220 HOH A O 1 HETATM 9700 O O . HOH I 8 . ? 38.517 54.238 -17.454 1.00 34.09 ? 2221 HOH A O 1 HETATM 9701 O O . HOH I 8 . ? 42.950 59.410 -18.727 1.00 22.65 ? 2222 HOH A O 1 HETATM 9702 O O . HOH I 8 . ? 45.739 59.954 -18.242 1.00 12.34 ? 2223 HOH A O 1 HETATM 9703 O O . HOH I 8 . ? 46.661 57.291 -18.754 1.00 13.81 ? 2224 HOH A O 1 HETATM 9704 O O . HOH I 8 . ? 58.940 53.766 -22.134 1.00 21.32 ? 2225 HOH A O 1 HETATM 9705 O O . HOH I 8 . ? 63.209 45.750 -22.304 1.00 59.75 ? 2226 HOH A O 1 HETATM 9706 O O . HOH I 8 . ? 63.080 42.909 -20.898 1.00 29.40 ? 2227 HOH A O 1 HETATM 9707 O O . HOH I 8 . ? 66.102 35.223 -13.150 1.00 54.30 ? 2228 HOH A O 1 HETATM 9708 O O . HOH I 8 . ? 63.955 34.810 -9.714 1.00 53.49 ? 2229 HOH A O 1 HETATM 9709 O O . HOH I 8 . ? 64.461 39.344 -10.169 1.00 22.01 ? 2230 HOH A O 1 HETATM 9710 O O . HOH I 8 . ? 67.113 38.445 -9.709 1.00 31.49 ? 2231 HOH A O 1 HETATM 9711 O O . HOH I 8 . ? 70.761 37.214 -11.279 1.00 44.82 ? 2232 HOH A O 1 HETATM 9712 O O . HOH I 8 . ? 71.123 39.877 -9.328 1.00 37.70 ? 2233 HOH A O 1 HETATM 9713 O O . HOH I 8 . ? 73.888 52.826 -5.777 1.00 28.21 ? 2234 HOH A O 1 HETATM 9714 O O . HOH I 8 . ? 60.203 54.369 14.874 1.00 39.10 ? 2235 HOH A O 1 HETATM 9715 O O A HOH I 8 . ? 61.020 57.400 15.563 0.50 23.51 ? 2236 HOH A O 1 HETATM 9716 O O B HOH I 8 . ? 61.662 59.341 14.837 0.50 20.78 ? 2236 HOH A O 1 HETATM 9717 O O . HOH I 8 . ? 63.345 59.507 16.866 1.00 40.35 ? 2237 HOH A O 1 HETATM 9718 O O . HOH I 8 . ? 62.299 56.958 17.720 1.00 40.10 ? 2238 HOH A O 1 HETATM 9719 O O . HOH I 8 . ? 53.403 52.819 26.240 1.00 29.90 ? 2239 HOH A O 1 HETATM 9720 O O . HOH I 8 . ? 56.594 54.125 29.673 1.00 44.82 ? 2240 HOH A O 1 HETATM 9721 O O . HOH I 8 . ? 53.931 49.379 29.784 1.00 37.50 ? 2241 HOH A O 1 HETATM 9722 O O . HOH I 8 . ? 55.177 46.350 30.841 1.00 40.01 ? 2242 HOH A O 1 HETATM 9723 O O . HOH I 8 . ? 49.543 50.794 32.537 1.00 30.60 ? 2243 HOH A O 1 HETATM 9724 O O . HOH I 8 . ? 47.051 53.215 35.660 1.00 48.80 ? 2244 HOH A O 1 HETATM 9725 O O . HOH I 8 . ? 47.019 55.838 36.638 1.00 59.14 ? 2245 HOH A O 1 HETATM 9726 O O . HOH I 8 . ? 51.979 60.273 28.056 1.00 30.53 ? 2246 HOH A O 1 HETATM 9727 O O . HOH I 8 . ? 50.903 62.104 26.366 1.00 20.73 ? 2247 HOH A O 1 HETATM 9728 O O . HOH I 8 . ? 51.960 63.909 24.581 1.00 29.65 ? 2248 HOH A O 1 HETATM 9729 O O . HOH I 8 . ? 47.826 66.285 26.872 1.00 27.05 ? 2249 HOH A O 1 HETATM 9730 O O . HOH I 8 . ? 48.113 63.609 28.617 1.00 58.45 ? 2250 HOH A O 1 HETATM 9731 O O . HOH I 8 . ? 42.082 67.466 29.305 1.00 24.58 ? 2251 HOH A O 1 HETATM 9732 O O . HOH I 8 . ? 39.834 67.125 31.279 1.00 22.62 ? 2252 HOH A O 1 HETATM 9733 O O . HOH I 8 . ? 48.807 71.748 25.659 1.00 53.58 ? 2253 HOH A O 1 HETATM 9734 O O . HOH I 8 . ? 47.916 74.016 25.036 1.00 51.47 ? 2254 HOH A O 1 HETATM 9735 O O . HOH I 8 . ? 49.311 74.506 23.040 1.00 44.24 ? 2255 HOH A O 1 HETATM 9736 O O . HOH I 8 . ? 45.954 74.256 22.627 1.00 35.11 ? 2256 HOH A O 1 HETATM 9737 O O . HOH I 8 . ? 52.119 71.798 21.858 1.00 41.44 ? 2257 HOH A O 1 HETATM 9738 O O . HOH I 8 . ? 51.112 76.479 14.324 1.00 21.61 ? 2258 HOH A O 1 HETATM 9739 O O . HOH I 8 . ? 51.667 77.773 11.920 1.00 37.78 ? 2259 HOH A O 1 HETATM 9740 O O . HOH I 8 . ? 38.737 76.959 17.770 1.00 45.57 ? 2260 HOH A O 1 HETATM 9741 O O . HOH I 8 . ? 36.169 81.100 6.319 1.00 20.30 ? 2261 HOH A O 1 HETATM 9742 O O . HOH I 8 . ? 33.267 83.085 4.175 1.00 49.61 ? 2262 HOH A O 1 HETATM 9743 O O . HOH I 8 . ? 30.856 83.415 4.913 1.00 30.71 ? 2263 HOH A O 1 HETATM 9744 O O . HOH I 8 . ? 30.115 82.515 7.301 1.00 38.96 ? 2264 HOH A O 1 HETATM 9745 O O . HOH I 8 . ? 31.920 80.507 7.152 1.00 40.82 ? 2265 HOH A O 1 HETATM 9746 O O . HOH I 8 . ? 30.241 85.783 1.662 1.00 31.22 ? 2266 HOH A O 1 HETATM 9747 O O . HOH I 8 . ? 30.979 87.018 -2.802 1.00 35.72 ? 2267 HOH A O 1 HETATM 9748 O O . HOH I 8 . ? 36.664 88.004 -11.887 1.00 47.44 ? 2268 HOH A O 1 HETATM 9749 O O . HOH I 8 . ? 36.810 86.471 -15.585 1.00 38.12 ? 2269 HOH A O 1 HETATM 9750 O O . HOH I 8 . ? 38.416 87.062 -17.473 1.00 41.99 ? 2270 HOH A O 1 HETATM 9751 O O . HOH I 8 . ? 38.305 86.913 -20.147 1.00 39.53 ? 2271 HOH A O 1 HETATM 9752 O O . HOH I 8 . ? 40.134 86.026 -21.959 1.00 24.44 ? 2272 HOH A O 1 HETATM 9753 O O . HOH I 8 . ? 42.640 86.447 -21.198 1.00 41.64 ? 2273 HOH A O 1 HETATM 9754 O O . HOH I 8 . ? 47.017 83.113 -21.027 1.00 39.55 ? 2274 HOH A O 1 HETATM 9755 O O . HOH I 8 . ? 46.871 80.616 -22.623 1.00 39.72 ? 2275 HOH A O 1 HETATM 9756 O O . HOH I 8 . ? 45.631 78.857 -24.231 1.00 44.93 ? 2276 HOH A O 1 HETATM 9757 O O . HOH I 8 . ? 46.337 77.080 -26.060 1.00 32.00 ? 2277 HOH A O 1 HETATM 9758 O O . HOH I 8 . ? 44.615 76.276 -28.206 1.00 33.78 ? 2278 HOH A O 1 HETATM 9759 O O . HOH I 8 . ? 42.940 78.288 -29.813 1.00 32.61 ? 2279 HOH A O 1 HETATM 9760 O O . HOH I 8 . ? 42.769 79.903 -28.103 1.00 39.22 ? 2280 HOH A O 1 HETATM 9761 O O . HOH I 8 . ? 42.383 82.404 -29.386 1.00 31.96 ? 2281 HOH A O 1 HETATM 9762 O O . HOH I 8 . ? 40.642 82.940 -31.212 1.00 25.19 ? 2282 HOH A O 1 HETATM 9763 O O . HOH I 8 . ? 38.224 81.722 -31.384 1.00 13.16 ? 2283 HOH A O 1 HETATM 9764 O O . HOH I 8 . ? 39.165 83.269 -27.393 1.00 21.75 ? 2284 HOH A O 1 HETATM 9765 O O . HOH I 8 . ? 41.491 83.474 -26.356 1.00 35.97 ? 2285 HOH A O 1 HETATM 9766 O O . HOH I 8 . ? 43.552 80.994 -25.296 1.00 34.83 ? 2286 HOH A O 1 HETATM 9767 O O . HOH I 8 . ? 45.990 82.050 -25.711 1.00 43.52 ? 2287 HOH A O 1 HETATM 9768 O O . HOH I 8 . ? 44.491 83.677 -28.195 1.00 28.47 ? 2288 HOH A O 1 HETATM 9769 O O . HOH I 8 . ? 44.777 82.563 -30.562 1.00 23.45 ? 2289 HOH A O 1 HETATM 9770 O O . HOH I 8 . ? 42.522 79.802 -31.763 1.00 32.58 ? 2290 HOH A O 1 HETATM 9771 O O . HOH I 8 . ? 44.701 79.212 -33.309 1.00 24.48 ? 2291 HOH A O 1 HETATM 9772 O O . HOH I 8 . ? 47.975 74.680 -29.454 1.00 35.63 ? 2292 HOH A O 1 HETATM 9773 O O . HOH I 8 . ? 50.544 73.752 -25.459 1.00 21.08 ? 2293 HOH A O 1 HETATM 9774 O O . HOH I 8 . ? 51.059 70.922 -23.656 1.00 18.86 ? 2294 HOH A O 1 HETATM 9775 O O . HOH I 8 . ? 47.499 79.565 -18.465 1.00 27.30 ? 2295 HOH A O 1 HETATM 9776 O O . HOH I 8 . ? 47.405 81.569 -17.064 1.00 36.00 ? 2296 HOH A O 1 HETATM 9777 O O . HOH I 8 . ? 44.035 79.228 -21.460 1.00 36.78 ? 2297 HOH A O 1 HETATM 9778 O O . HOH I 8 . ? 41.905 79.279 -23.388 1.00 25.33 ? 2298 HOH A O 1 HETATM 9779 O O . HOH I 8 . ? 39.680 81.603 -21.945 1.00 32.45 ? 2299 HOH A O 1 HETATM 9780 O O . HOH I 8 . ? 35.418 86.254 -17.975 1.00 29.60 ? 2300 HOH A O 1 HETATM 9781 O O . HOH I 8 . ? 35.154 88.049 -19.820 1.00 39.67 ? 2301 HOH A O 1 HETATM 9782 O O . HOH I 8 . ? 33.658 88.117 -16.223 1.00 37.24 ? 2302 HOH A O 1 HETATM 9783 O O . HOH I 8 . ? 33.365 84.345 -18.312 1.00 18.77 ? 2303 HOH A O 1 HETATM 9784 O O . HOH I 8 . ? 31.647 85.884 -19.788 1.00 24.15 ? 2304 HOH A O 1 HETATM 9785 O O . HOH I 8 . ? 37.336 92.589 -18.177 1.00 39.44 ? 2305 HOH A O 1 HETATM 9786 O O . HOH I 8 . ? 41.616 95.301 -23.802 1.00 68.60 ? 2306 HOH A O 1 HETATM 9787 O O . HOH I 8 . ? 43.610 93.613 -23.915 1.00 37.81 ? 2307 HOH A O 1 HETATM 9788 O O . HOH I 8 . ? 45.171 92.600 -25.436 1.00 29.64 ? 2308 HOH A O 1 HETATM 9789 O O . HOH I 8 . ? 45.136 89.937 -25.491 1.00 19.07 ? 2309 HOH A O 1 HETATM 9790 O O . HOH I 8 . ? 46.974 89.500 -23.694 1.00 30.48 ? 2310 HOH A O 1 HETATM 9791 O O . HOH I 8 . ? 45.618 95.225 -26.565 1.00 33.12 ? 2311 HOH A O 1 HETATM 9792 O O . HOH I 8 . ? 44.589 95.551 -30.515 1.00 38.56 ? 2312 HOH A O 1 HETATM 9793 O O . HOH I 8 . ? 42.585 94.289 -30.529 1.00 37.55 ? 2313 HOH A O 1 HETATM 9794 O O . HOH I 8 . ? 41.609 96.360 -29.724 1.00 51.48 ? 2314 HOH A O 1 HETATM 9795 O O . HOH I 8 . ? 40.174 99.881 -32.020 1.00 29.82 ? 2315 HOH A O 1 HETATM 9796 O O . HOH I 8 . ? 35.156 94.877 -32.268 1.00 24.93 ? 2316 HOH A O 1 HETATM 9797 O O . HOH I 8 . ? 36.146 93.469 -30.068 1.00 32.04 ? 2317 HOH A O 1 HETATM 9798 O O . HOH I 8 . ? 31.572 96.777 -27.353 1.00 43.51 ? 2318 HOH A O 1 HETATM 9799 O O . HOH I 8 . ? 25.334 98.326 -35.131 1.00 47.01 ? 2319 HOH A O 1 HETATM 9800 O O . HOH I 8 . ? 28.802 93.703 -38.554 1.00 27.00 ? 2320 HOH A O 1 HETATM 9801 O O . HOH I 8 . ? 31.974 92.399 -36.933 1.00 24.88 ? 2321 HOH A O 1 HETATM 9802 O O . HOH I 8 . ? 28.072 84.499 -35.469 1.00 16.76 ? 2322 HOH A O 1 HETATM 9803 O O . HOH I 8 . ? 28.981 81.825 -35.669 1.00 17.47 ? 2323 HOH A O 1 HETATM 9804 O O . HOH I 8 . ? 22.060 80.145 -35.939 1.00 24.66 ? 2324 HOH A O 1 HETATM 9805 O O . HOH I 8 . ? 20.700 80.031 -33.562 1.00 37.84 ? 2325 HOH A O 1 HETATM 9806 O O . HOH I 8 . ? 23.029 78.479 -30.293 1.00 22.64 ? 2326 HOH A O 1 HETATM 9807 O O . HOH I 8 . ? 30.308 74.836 -29.218 1.00 13.92 ? 2327 HOH A O 1 HETATM 9808 O O . HOH I 8 . ? 32.423 77.622 -29.665 1.00 13.58 ? 2328 HOH A O 1 HETATM 9809 O O . HOH I 8 . ? 38.712 83.411 -39.737 1.00 24.41 ? 2329 HOH A O 1 HETATM 9810 O O . HOH I 8 . ? 36.870 82.329 -41.316 1.00 42.45 ? 2330 HOH A O 1 HETATM 9811 O O . HOH I 8 . ? 40.065 82.991 -43.973 1.00 48.20 ? 2331 HOH A O 1 HETATM 9812 O O . HOH I 8 . ? 43.925 79.918 -42.550 1.00 28.10 ? 2332 HOH A O 1 HETATM 9813 O O . HOH I 8 . ? 46.650 80.220 -42.562 1.00 24.27 ? 2333 HOH A O 1 HETATM 9814 O O . HOH I 8 . ? 47.626 78.912 -40.414 1.00 19.72 ? 2334 HOH A O 1 HETATM 9815 O O . HOH I 8 . ? 48.345 80.315 -44.794 1.00 47.87 ? 2335 HOH A O 1 HETATM 9816 O O . HOH I 8 . ? 49.883 82.286 -43.827 1.00 18.10 ? 2336 HOH A O 1 HETATM 9817 O O . HOH I 8 . ? 47.639 83.935 -43.884 1.00 46.64 ? 2337 HOH A O 1 HETATM 9818 O O . HOH I 8 . ? 45.391 83.636 -43.087 1.00 38.42 ? 2338 HOH A O 1 HETATM 9819 O O . HOH I 8 . ? 43.418 77.257 -43.112 1.00 45.38 ? 2339 HOH A O 1 HETATM 9820 O O . HOH I 8 . ? 51.414 76.159 -40.885 1.00 29.21 ? 2340 HOH A O 1 HETATM 9821 O O . HOH I 8 . ? 53.546 76.846 -43.647 1.00 38.60 ? 2341 HOH A O 1 HETATM 9822 O O . HOH I 8 . ? 53.304 79.226 -44.771 1.00 36.86 ? 2342 HOH A O 1 HETATM 9823 O O . HOH I 8 . ? 51.116 80.342 -45.514 1.00 48.97 ? 2343 HOH A O 1 HETATM 9824 O O . HOH I 8 . ? 54.379 82.862 -44.452 1.00 45.20 ? 2344 HOH A O 1 HETATM 9825 O O . HOH I 8 . ? 55.515 87.408 -47.895 1.00 55.09 ? 2345 HOH A O 1 HETATM 9826 O O . HOH I 8 . ? 57.144 88.925 -46.171 1.00 40.29 ? 2346 HOH A O 1 HETATM 9827 O O . HOH I 8 . ? 56.775 89.831 -43.713 1.00 36.66 ? 2347 HOH A O 1 HETATM 9828 O O . HOH I 8 . ? 54.171 90.601 -43.166 1.00 33.22 ? 2348 HOH A O 1 HETATM 9829 O O . HOH I 8 . ? 53.635 92.937 -40.340 1.00 41.75 ? 2349 HOH A O 1 HETATM 9830 O O . HOH I 8 . ? 56.385 94.234 -38.592 1.00 64.85 ? 2350 HOH A O 1 HETATM 9831 O O . HOH I 8 . ? 59.153 86.982 -46.026 1.00 43.80 ? 2351 HOH A O 1 HETATM 9832 O O . HOH I 8 . ? 62.143 81.467 -44.327 1.00 39.54 ? 2352 HOH A O 1 HETATM 9833 O O . HOH I 8 . ? 60.806 78.784 -41.581 1.00 26.05 ? 2353 HOH A O 1 HETATM 9834 O O . HOH I 8 . ? 61.534 76.663 -39.753 1.00 21.95 ? 2354 HOH A O 1 HETATM 9835 O O . HOH I 8 . ? 64.088 77.002 -40.350 1.00 35.17 ? 2355 HOH A O 1 HETATM 9836 O O . HOH I 8 . ? 64.025 78.510 -37.793 1.00 27.30 ? 2356 HOH A O 1 HETATM 9837 O O . HOH I 8 . ? 64.384 77.917 -35.261 1.00 14.83 ? 2357 HOH A O 1 HETATM 9838 O O . HOH I 8 . ? 61.992 83.089 -38.318 1.00 24.40 ? 2358 HOH A O 1 HETATM 9839 O O . HOH I 8 . ? 65.588 87.519 -41.348 1.00 40.28 ? 2359 HOH A O 1 HETATM 9840 O O . HOH I 8 . ? 71.485 85.986 -36.041 1.00 50.45 ? 2360 HOH A O 1 HETATM 9841 O O . HOH I 8 . ? 73.092 85.615 -33.924 1.00 52.75 ? 2361 HOH A O 1 HETATM 9842 O O . HOH I 8 . ? 72.069 82.805 -31.796 1.00 47.26 ? 2362 HOH A O 1 HETATM 9843 O O . HOH I 8 . ? 70.084 83.049 -29.815 1.00 23.35 ? 2363 HOH A O 1 HETATM 9844 O O . HOH I 8 . ? 71.452 82.421 -27.548 1.00 46.76 ? 2364 HOH A O 1 HETATM 9845 O O . HOH I 8 . ? 67.834 81.703 -25.624 1.00 14.74 ? 2365 HOH A O 1 HETATM 9846 O O . HOH I 8 . ? 67.818 78.967 -25.265 1.00 13.02 ? 2366 HOH A O 1 HETATM 9847 O O . HOH I 8 . ? 70.563 78.048 -26.062 1.00 24.23 ? 2367 HOH A O 1 HETATM 9848 O O . HOH I 8 . ? 68.447 79.358 -28.559 1.00 24.09 ? 2368 HOH A O 1 HETATM 9849 O O . HOH I 8 . ? 70.316 77.367 -31.684 1.00 49.84 ? 2369 HOH A O 1 HETATM 9850 O O A HOH I 8 . ? 63.505 67.902 -31.709 0.50 17.03 ? 2370 HOH A O 1 HETATM 9851 O O B HOH I 8 . ? 65.167 67.913 -31.169 0.50 18.40 ? 2370 HOH A O 1 HETATM 9852 O O . HOH I 8 . ? 64.103 65.491 -30.558 1.00 43.65 ? 2371 HOH A O 1 HETATM 9853 O O . HOH I 8 . ? 61.848 63.868 -30.604 1.00 25.66 ? 2372 HOH A O 1 HETATM 9854 O O . HOH I 8 . ? 59.570 67.143 -34.688 1.00 26.04 ? 2373 HOH A O 1 HETATM 9855 O O . HOH I 8 . ? 61.272 67.528 -36.601 1.00 32.23 ? 2374 HOH A O 1 HETATM 9856 O O . HOH I 8 . ? 61.635 68.971 -41.685 1.00 30.50 ? 2375 HOH A O 1 HETATM 9857 O O . HOH I 8 . ? 66.114 74.649 -41.216 1.00 39.38 ? 2376 HOH A O 1 HETATM 9858 O O . HOH I 8 . ? 63.850 77.069 -44.499 1.00 45.25 ? 2377 HOH A O 1 HETATM 9859 O O . HOH I 8 . ? 63.264 74.699 -46.030 1.00 36.76 ? 2378 HOH A O 1 HETATM 9860 O O . HOH I 8 . ? 55.489 74.321 -43.149 1.00 51.80 ? 2379 HOH A O 1 HETATM 9861 O O . HOH I 8 . ? 58.435 77.268 -38.518 1.00 14.77 ? 2380 HOH A O 1 HETATM 9862 O O . HOH I 8 . ? 54.011 64.228 -38.362 1.00 26.41 ? 2381 HOH A O 1 HETATM 9863 O O . HOH I 8 . ? 47.427 67.772 -33.850 1.00 39.42 ? 2382 HOH A O 1 HETATM 9864 O O . HOH I 8 . ? 55.000 81.066 -23.619 1.00 14.80 ? 2383 HOH A O 1 HETATM 9865 O O . HOH I 8 . ? 53.137 86.778 -21.444 1.00 27.63 ? 2384 HOH A O 1 HETATM 9866 O O . HOH I 8 . ? 56.851 87.658 -20.041 1.00 28.38 ? 2385 HOH A O 1 HETATM 9867 O O . HOH I 8 . ? 59.290 87.205 -20.545 1.00 35.61 ? 2386 HOH A O 1 HETATM 9868 O O . HOH I 8 . ? 56.431 90.037 -21.256 1.00 34.20 ? 2387 HOH A O 1 HETATM 9869 O O . HOH I 8 . ? 26.958 72.249 20.865 1.00 39.79 ? 2388 HOH A O 1 HETATM 9870 O O . HOH I 8 . ? 64.138 89.639 -22.244 1.00 25.87 ? 2389 HOH A O 1 HETATM 9871 O O . HOH I 8 . ? 66.593 89.124 -21.198 1.00 40.26 ? 2390 HOH A O 1 HETATM 9872 O O . HOH I 8 . ? 67.726 88.137 -23.334 1.00 25.11 ? 2391 HOH A O 1 HETATM 9873 O O . HOH I 8 . ? 65.140 87.959 -24.198 1.00 27.55 ? 2392 HOH A O 1 HETATM 9874 O O . HOH I 8 . ? 62.319 85.617 -22.968 1.00 31.87 ? 2393 HOH A O 1 HETATM 9875 O O . HOH I 8 . ? 64.160 84.072 -19.404 1.00 46.93 ? 2394 HOH A O 1 HETATM 9876 O O . HOH I 8 . ? 62.709 82.653 -17.067 1.00 41.26 ? 2395 HOH A O 1 HETATM 9877 O O . HOH I 8 . ? 62.161 80.700 -18.859 1.00 22.48 ? 2396 HOH A O 1 HETATM 9878 O O . HOH I 8 . ? 60.187 83.843 -16.716 1.00 37.42 ? 2397 HOH A O 1 HETATM 9879 O O . HOH I 8 . ? 63.595 82.150 -14.400 1.00 40.90 ? 2398 HOH A O 1 HETATM 9880 O O . HOH I 8 . ? 66.546 81.789 -14.297 1.00 28.65 ? 2399 HOH A O 1 HETATM 9881 O O . HOH I 8 . ? 66.934 81.417 -11.246 1.00 33.04 ? 2400 HOH A O 1 HETATM 9882 O O . HOH I 8 . ? 65.144 79.778 -8.808 1.00 40.87 ? 2401 HOH A O 1 HETATM 9883 O O . HOH I 8 . ? 74.185 80.048 -10.454 1.00 45.83 ? 2402 HOH A O 1 HETATM 9884 O O . HOH I 8 . ? 73.620 78.922 -13.246 1.00 50.70 ? 2403 HOH A O 1 HETATM 9885 O O . HOH I 8 . ? 71.478 84.012 -14.647 1.00 45.04 ? 2404 HOH A O 1 HETATM 9886 O O . HOH I 8 . ? 71.863 84.514 -20.007 1.00 33.29 ? 2405 HOH A O 1 HETATM 9887 O O . HOH I 8 . ? 73.422 82.347 -21.150 1.00 26.74 ? 2406 HOH A O 1 HETATM 9888 O O . HOH I 8 . ? 75.309 83.672 -22.829 1.00 37.58 ? 2407 HOH A O 1 HETATM 9889 O O . HOH I 8 . ? 74.176 86.448 -23.287 1.00 46.66 ? 2408 HOH A O 1 HETATM 9890 O O . HOH I 8 . ? 71.887 87.607 -27.710 1.00 45.19 ? 2409 HOH A O 1 HETATM 9891 O O . HOH I 8 . ? 66.949 84.410 -22.169 1.00 26.62 ? 2410 HOH A O 1 HETATM 9892 O O . HOH I 8 . ? 68.650 78.841 -18.058 1.00 21.98 ? 2411 HOH A O 1 HETATM 9893 O O . HOH I 8 . ? 46.928 87.931 -13.580 1.00 40.02 ? 2412 HOH A O 1 HETATM 9894 O O . HOH I 8 . ? 40.807 85.213 -12.194 1.00 26.42 ? 2413 HOH A O 1 HETATM 9895 O O . HOH I 8 . ? 5.401 81.249 -3.323 1.00 37.89 ? 2414 HOH A O 1 HETATM 9896 O O A HOH I 8 . ? 26.616 74.806 2.266 0.50 10.53 ? 2415 HOH A O 1 HETATM 9897 O O B HOH I 8 . ? 26.301 75.858 1.547 0.50 14.53 ? 2415 HOH A O 1 HETATM 9898 O O . HOH I 8 . ? 26.179 72.743 5.554 1.00 12.08 ? 2416 HOH A O 1 HETATM 9899 O O . HOH I 8 . ? 25.323 73.731 8.722 1.00 21.62 ? 2417 HOH A O 1 HETATM 9900 O O . HOH I 8 . ? 26.384 74.982 10.999 1.00 29.57 ? 2418 HOH A O 1 HETATM 9901 O O . HOH I 8 . ? 22.824 72.520 10.875 1.00 46.88 ? 2419 HOH A O 1 HETATM 9902 O O . HOH I 8 . ? 24.449 70.636 11.139 1.00 45.47 ? 2420 HOH A O 1 HETATM 9903 O O . HOH I 8 . ? 20.199 72.584 11.242 1.00 51.05 ? 2421 HOH A O 1 HETATM 9904 O O . HOH I 8 . ? 18.621 70.450 10.385 1.00 48.40 ? 2422 HOH A O 1 HETATM 9905 O O . HOH I 8 . ? 16.878 68.407 10.674 1.00 46.69 ? 2423 HOH A O 1 HETATM 9906 O O . HOH I 8 . ? 15.689 70.154 6.496 1.00 26.34 ? 2424 HOH A O 1 HETATM 9907 O O . HOH I 8 . ? 15.618 73.584 5.509 1.00 24.86 ? 2425 HOH A O 1 HETATM 9908 O O . HOH I 8 . ? 17.727 74.447 3.873 1.00 20.28 ? 2426 HOH A O 1 HETATM 9909 O O . HOH I 8 . ? 19.280 72.472 3.045 1.00 15.97 ? 2427 HOH A O 1 HETATM 9910 O O . HOH I 8 . ? 18.611 70.016 4.204 1.00 14.38 ? 2428 HOH A O 1 HETATM 9911 O O . HOH I 8 . ? 19.127 76.597 4.695 1.00 24.36 ? 2429 HOH A O 1 HETATM 9912 O O . HOH I 8 . ? 19.726 77.072 7.272 1.00 61.22 ? 2430 HOH A O 1 HETATM 9913 O O . HOH I 8 . ? 21.975 76.406 8.570 1.00 29.87 ? 2431 HOH A O 1 HETATM 9914 O O . HOH I 8 . ? 21.341 78.811 7.584 1.00 49.76 ? 2432 HOH A O 1 HETATM 9915 O O . HOH I 8 . ? 21.756 79.917 5.331 1.00 26.16 ? 2433 HOH A O 1 HETATM 9916 O O . HOH I 8 . ? 16.911 74.566 -3.000 1.00 13.21 ? 2434 HOH A O 1 HETATM 9917 O O . HOH I 8 . ? 20.157 74.332 -6.766 1.00 12.50 ? 2435 HOH A O 1 HETATM 9918 O O . HOH I 8 . ? 24.681 70.580 -8.728 1.00 11.86 ? 2436 HOH A O 1 HETATM 9919 O O . HOH I 8 . ? 26.839 68.935 -9.221 1.00 8.76 ? 2437 HOH A O 1 HETATM 9920 O O . HOH I 8 . ? 32.658 64.710 -9.977 1.00 17.54 ? 2438 HOH A O 1 HETATM 9921 O O . HOH I 8 . ? 34.296 58.587 -8.757 1.00 7.64 ? 2439 HOH A O 1 HETATM 9922 O O . HOH I 8 . ? 30.262 58.434 -11.776 1.00 7.43 ? 2440 HOH A O 1 HETATM 9923 O O . HOH I 8 . ? 26.826 60.954 -3.286 1.00 8.34 ? 2441 HOH A O 1 HETATM 9924 O O . HOH I 8 . ? 20.684 57.445 -5.181 1.00 10.41 ? 2442 HOH A O 1 HETATM 9925 O O . HOH I 8 . ? 21.564 57.988 -7.698 1.00 8.94 ? 2443 HOH A O 1 HETATM 9926 O O . HOH I 8 . ? 19.872 57.385 -11.726 1.00 14.41 ? 2444 HOH A O 1 HETATM 9927 O O . HOH I 8 . ? 11.837 54.983 -12.312 1.00 19.27 ? 2445 HOH A O 1 HETATM 9928 O O . HOH I 8 . ? 8.002 57.781 -11.573 1.00 38.23 ? 2446 HOH A O 1 HETATM 9929 O O . HOH I 8 . ? 7.199 56.721 -8.931 1.00 47.08 ? 2447 HOH A O 1 HETATM 9930 O O . HOH I 8 . ? 8.676 57.652 -6.833 1.00 25.98 ? 2448 HOH A O 1 HETATM 9931 O O . HOH I 8 . ? 8.719 54.984 -6.013 1.00 29.13 ? 2449 HOH A O 1 HETATM 9932 O O . HOH I 8 . ? 4.387 56.680 -6.167 1.00 38.88 ? 2450 HOH A O 1 HETATM 9933 O O . HOH I 8 . ? 5.556 57.954 7.068 1.00 31.31 ? 2451 HOH A O 1 HETATM 9934 O O . HOH I 8 . ? 4.629 59.086 11.258 1.00 49.59 ? 2452 HOH A O 1 HETATM 9935 O O . HOH I 8 . ? 9.050 50.517 8.172 1.00 29.68 ? 2453 HOH A O 1 HETATM 9936 O O . HOH I 8 . ? 8.636 49.368 5.609 1.00 43.68 ? 2454 HOH A O 1 HETATM 9937 O O . HOH I 8 . ? 11.875 51.616 14.381 1.00 17.09 ? 2455 HOH A O 1 HETATM 9938 O O . HOH I 8 . ? 14.096 49.122 15.507 1.00 16.81 ? 2456 HOH A O 1 HETATM 9939 O O . HOH I 8 . ? 17.401 41.700 9.262 1.00 27.43 ? 2457 HOH A O 1 HETATM 9940 O O . HOH I 8 . ? 16.581 38.459 5.973 1.00 48.19 ? 2458 HOH A O 1 HETATM 9941 O O . HOH I 8 . ? 18.369 36.782 5.762 1.00 34.95 ? 2459 HOH A O 1 HETATM 9942 O O . HOH I 8 . ? 31.141 33.602 2.863 1.00 24.39 ? 2460 HOH A O 1 HETATM 9943 O O . HOH I 8 . ? 30.746 29.766 5.921 1.00 38.88 ? 2461 HOH A O 1 HETATM 9944 O O . HOH I 8 . ? 37.009 34.096 5.582 1.00 45.14 ? 2462 HOH A O 1 HETATM 9945 O O . HOH I 8 . ? 38.925 33.328 6.830 1.00 43.58 ? 2463 HOH A O 1 HETATM 9946 O O . HOH I 8 . ? 47.726 40.169 5.959 1.00 34.93 ? 2464 HOH A O 1 HETATM 9947 O O . HOH I 8 . ? 51.055 40.376 5.025 1.00 49.44 ? 2465 HOH A O 1 HETATM 9948 O O . HOH I 8 . ? 41.301 59.061 13.503 1.00 10.49 ? 2466 HOH A O 1 HETATM 9949 O O . HOH I 8 . ? 39.416 57.460 14.855 1.00 9.16 ? 2467 HOH A O 1 HETATM 9950 O O . HOH I 8 . ? 36.956 57.736 13.397 1.00 9.59 ? 2468 HOH A O 1 HETATM 9951 O O . HOH I 8 . ? 37.679 59.095 11.059 1.00 10.67 ? 2469 HOH A O 1 HETATM 9952 O O . HOH I 8 . ? 30.281 55.877 17.147 1.00 9.73 ? 2470 HOH A O 1 HETATM 9953 O O . HOH I 8 . ? 27.809 53.459 20.052 1.00 15.01 ? 2471 HOH A O 1 HETATM 9954 O O . HOH I 8 . ? 27.152 52.316 22.489 1.00 26.13 ? 2472 HOH A O 1 HETATM 9955 O O . HOH I 8 . ? 27.523 50.260 23.213 1.00 29.25 ? 2473 HOH A O 1 HETATM 9956 O O . HOH I 8 . ? 33.749 60.408 23.278 1.00 12.73 ? 2474 HOH A O 1 HETATM 9957 O O . HOH I 8 . ? 23.098 65.074 14.122 1.00 41.71 ? 2475 HOH A O 1 HETATM 9958 O O . HOH I 8 . ? 12.154 71.376 4.812 1.00 36.94 ? 2476 HOH A O 1 HETATM 9959 O O . HOH I 8 . ? 10.371 77.275 4.035 1.00 45.33 ? 2477 HOH A O 1 HETATM 9960 O O . HOH I 8 . ? 19.569 67.315 -2.669 1.00 26.65 ? 2478 HOH A O 1 HETATM 9961 O O . HOH I 8 . ? 20.322 58.768 -21.899 1.00 10.57 ? 2479 HOH A O 1 HETATM 9962 O O . HOH I 8 . ? 23.826 55.489 -23.349 1.00 10.25 ? 2480 HOH A O 1 HETATM 9963 O O . HOH I 8 . ? 16.985 50.861 -19.218 1.00 24.01 ? 2481 HOH A O 1 HETATM 9964 O O . HOH I 8 . ? 18.380 48.850 -19.808 1.00 38.23 ? 2482 HOH A O 1 HETATM 9965 O O . HOH I 8 . ? 14.432 51.029 -18.377 1.00 54.28 ? 2483 HOH A O 1 HETATM 9966 O O . HOH I 8 . ? 48.691 96.141 -44.349 1.00 46.42 ? 2484 HOH A O 1 HETATM 9967 O O . HOH I 8 . ? 23.879 39.291 -21.033 1.00 36.90 ? 2485 HOH A O 1 HETATM 9968 O O . HOH I 8 . ? 28.595 41.276 -21.613 1.00 14.21 ? 2486 HOH A O 1 HETATM 9969 O O . HOH I 8 . ? 15.154 53.894 -32.074 1.00 36.57 ? 2487 HOH A O 1 HETATM 9970 O O . HOH I 8 . ? 28.608 58.203 -48.625 1.00 54.95 ? 2488 HOH A O 1 HETATM 9971 O O . HOH I 8 . ? 23.128 78.495 -42.062 1.00 40.89 ? 2489 HOH A O 1 HETATM 9972 O O . HOH I 8 . ? 23.360 82.528 -40.560 1.00 25.20 ? 2490 HOH A O 1 HETATM 9973 O O . HOH I 8 . ? 21.258 82.083 -37.816 1.00 38.82 ? 2491 HOH A O 1 HETATM 9974 O O . HOH I 8 . ? 23.246 88.584 -38.276 1.00 34.53 ? 2492 HOH A O 1 HETATM 9975 O O . HOH I 8 . ? 27.923 102.142 -19.157 1.00 32.27 ? 2493 HOH A O 1 HETATM 9976 O O . HOH I 8 . ? 26.562 100.852 -15.260 1.00 41.36 ? 2494 HOH A O 1 HETATM 9977 O O . HOH I 8 . ? 48.383 89.166 -30.767 1.00 14.95 ? 2495 HOH A O 1 HETATM 9978 O O . HOH I 8 . ? 68.247 66.047 -40.588 1.00 13.18 ? 2496 HOH A O 1 HETATM 9979 O O . HOH I 8 . ? 67.464 64.593 -38.412 1.00 17.90 ? 2497 HOH A O 1 HETATM 9980 O O . HOH I 8 . ? 18.351 29.060 23.489 1.00 40.37 ? 2498 HOH A O 1 HETATM 9981 O O . HOH I 8 . ? 19.705 81.589 -42.493 1.00 42.88 ? 2499 HOH A O 1 HETATM 9982 O O . HOH I 8 . ? 21.311 82.514 -44.292 1.00 49.12 ? 2500 HOH A O 1 HETATM 9983 O O . HOH I 8 . ? 22.181 80.724 -42.248 1.00 27.21 ? 2501 HOH A O 1 HETATM 9984 O O . HOH I 8 . ? 11.397 33.756 22.924 1.00 37.46 ? 2502 HOH A O 1 HETATM 9985 O O . HOH I 8 . ? 22.108 29.066 28.217 1.00 42.02 ? 2503 HOH A O 1 HETATM 9986 O O . HOH I 8 . ? 22.272 35.090 35.024 1.00 34.54 ? 2504 HOH A O 1 HETATM 9987 O O . HOH I 8 . ? 24.790 34.584 35.907 1.00 35.73 ? 2505 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 30 GLN GLN A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ALA 204 204 204 ALA ALA A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASP 341 341 341 ASP ASP A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 1045 SER SER A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 1046 1 NAG NAG A . C 3 PO4 1 1047 1 PO4 PO4 A . D 4 ZN 1 1048 1 ZN ZN A . E 5 MRD 1 1049 1 MRD MRD A . F 6 WZ1 1 1050 1 WZ1 WZ1 A . G 7 MPD 1 1051 1 MPD MPD A . H 7 MPD 1 1052 2 MPD MPD A . I 8 HOH 1 1053 1 HOH HOH A . I 8 HOH 2 1054 2 HOH HOH A . I 8 HOH 3 1055 3 HOH HOH A . I 8 HOH 4 1056 4 HOH HOH A . I 8 HOH 5 1057 5 HOH HOH A . I 8 HOH 6 1058 6 HOH HOH A . I 8 HOH 7 1059 7 HOH HOH A . I 8 HOH 8 1060 8 HOH HOH A . I 8 HOH 9 1061 9 HOH HOH A . I 8 HOH 10 1062 10 HOH HOH A . I 8 HOH 11 1063 11 HOH HOH A . I 8 HOH 12 1064 12 HOH HOH A . I 8 HOH 13 1065 13 HOH HOH A . I 8 HOH 14 1066 14 HOH HOH A . I 8 HOH 15 1067 15 HOH HOH A . I 8 HOH 16 1068 16 HOH HOH A . I 8 HOH 17 1069 17 HOH HOH A . I 8 HOH 18 1070 18 HOH HOH A . I 8 HOH 19 1071 19 HOH HOH A . I 8 HOH 20 1072 20 HOH HOH A . I 8 HOH 21 1073 21 HOH HOH A . I 8 HOH 22 1074 22 HOH HOH A . I 8 HOH 23 1075 23 HOH HOH A . I 8 HOH 24 1076 24 HOH HOH A . I 8 HOH 25 1077 25 HOH HOH A . I 8 HOH 26 1078 26 HOH HOH A . I 8 HOH 27 1079 27 HOH HOH A . I 8 HOH 28 1080 28 HOH HOH A . I 8 HOH 29 1081 29 HOH HOH A . I 8 HOH 30 1082 30 HOH HOH A . I 8 HOH 31 1083 31 HOH HOH A . I 8 HOH 32 1084 32 HOH HOH A . I 8 HOH 33 1085 33 HOH HOH A . I 8 HOH 34 1086 34 HOH HOH A . I 8 HOH 35 1087 35 HOH HOH A . I 8 HOH 36 1088 36 HOH HOH A . I 8 HOH 37 1089 37 HOH HOH A . I 8 HOH 38 1090 38 HOH HOH A . I 8 HOH 39 1091 39 HOH HOH A . I 8 HOH 40 1092 40 HOH HOH A . I 8 HOH 41 1093 41 HOH HOH A . I 8 HOH 42 1094 42 HOH HOH A . I 8 HOH 43 1095 43 HOH HOH A . I 8 HOH 44 1096 44 HOH HOH A . I 8 HOH 45 1097 45 HOH HOH A . I 8 HOH 46 1098 46 HOH HOH A . I 8 HOH 47 1099 47 HOH HOH A . I 8 HOH 48 1100 48 HOH HOH A . I 8 HOH 49 1101 49 HOH HOH A . I 8 HOH 50 1102 50 HOH HOH A . I 8 HOH 51 1103 51 HOH HOH A . I 8 HOH 52 1104 52 HOH HOH A . I 8 HOH 53 1105 53 HOH HOH A . I 8 HOH 54 1106 54 HOH HOH A . I 8 HOH 55 1107 55 HOH HOH A . I 8 HOH 56 1108 56 HOH HOH A . I 8 HOH 57 1109 57 HOH HOH A . I 8 HOH 58 1110 58 HOH HOH A . I 8 HOH 59 1111 59 HOH HOH A . I 8 HOH 60 1112 60 HOH HOH A . I 8 HOH 61 1113 61 HOH HOH A . I 8 HOH 62 1114 62 HOH HOH A . I 8 HOH 63 1115 63 HOH HOH A . I 8 HOH 64 1116 64 HOH HOH A . I 8 HOH 65 1117 65 HOH HOH A . I 8 HOH 66 1118 66 HOH HOH A . I 8 HOH 67 1119 67 HOH HOH A . I 8 HOH 68 1120 68 HOH HOH A . I 8 HOH 69 1121 69 HOH HOH A . I 8 HOH 70 1122 70 HOH HOH A . I 8 HOH 71 1123 71 HOH HOH A . I 8 HOH 72 1124 72 HOH HOH A . I 8 HOH 73 1125 73 HOH HOH A . I 8 HOH 74 1126 74 HOH HOH A . I 8 HOH 75 1127 75 HOH HOH A . I 8 HOH 76 1128 76 HOH HOH A . I 8 HOH 77 1129 77 HOH HOH A . I 8 HOH 78 1130 78 HOH HOH A . I 8 HOH 79 1131 79 HOH HOH A . I 8 HOH 80 1132 80 HOH HOH A . I 8 HOH 81 1133 81 HOH HOH A . I 8 HOH 82 1134 82 HOH HOH A . I 8 HOH 83 1135 83 HOH HOH A . I 8 HOH 84 1136 84 HOH HOH A . I 8 HOH 85 1137 85 HOH HOH A . I 8 HOH 86 1138 86 HOH HOH A . I 8 HOH 87 1139 87 HOH HOH A . I 8 HOH 88 1140 88 HOH HOH A . I 8 HOH 89 1141 89 HOH HOH A . I 8 HOH 90 1142 90 HOH HOH A . I 8 HOH 91 1143 91 HOH HOH A . I 8 HOH 92 1144 92 HOH HOH A . I 8 HOH 93 1145 93 HOH HOH A . I 8 HOH 94 1146 94 HOH HOH A . I 8 HOH 95 1147 95 HOH HOH A . I 8 HOH 96 1148 96 HOH HOH A . I 8 HOH 97 1149 97 HOH HOH A . I 8 HOH 98 1150 98 HOH HOH A . I 8 HOH 99 1151 99 HOH HOH A . I 8 HOH 100 1152 100 HOH HOH A . I 8 HOH 101 1153 101 HOH HOH A . I 8 HOH 102 1154 102 HOH HOH A . I 8 HOH 103 1155 103 HOH HOH A . I 8 HOH 104 1156 104 HOH HOH A . I 8 HOH 105 1157 105 HOH HOH A . I 8 HOH 106 1158 106 HOH HOH A . I 8 HOH 107 1159 107 HOH HOH A . I 8 HOH 108 1160 108 HOH HOH A . I 8 HOH 109 1161 109 HOH HOH A . I 8 HOH 110 1162 110 HOH HOH A . I 8 HOH 111 1163 111 HOH HOH A . I 8 HOH 112 1164 112 HOH HOH A . I 8 HOH 113 1165 113 HOH HOH A . I 8 HOH 114 1166 114 HOH HOH A . I 8 HOH 115 1167 115 HOH HOH A . I 8 HOH 116 1168 116 HOH HOH A . I 8 HOH 117 1169 117 HOH HOH A . I 8 HOH 118 1170 118 HOH HOH A . I 8 HOH 119 1171 119 HOH HOH A . I 8 HOH 120 1172 120 HOH HOH A . I 8 HOH 121 1173 121 HOH HOH A . I 8 HOH 122 1174 122 HOH HOH A . I 8 HOH 123 1175 123 HOH HOH A . I 8 HOH 124 1176 124 HOH HOH A . I 8 HOH 125 1177 125 HOH HOH A . I 8 HOH 126 1178 126 HOH HOH A . I 8 HOH 127 1179 127 HOH HOH A . I 8 HOH 128 1180 128 HOH HOH A . I 8 HOH 129 1181 129 HOH HOH A . I 8 HOH 130 1182 130 HOH HOH A . I 8 HOH 131 1183 131 HOH HOH A . I 8 HOH 132 1184 132 HOH HOH A . I 8 HOH 133 1185 133 HOH HOH A . I 8 HOH 134 1186 134 HOH HOH A . I 8 HOH 135 1187 135 HOH HOH A . I 8 HOH 136 1188 136 HOH HOH A . I 8 HOH 137 1189 137 HOH HOH A . I 8 HOH 138 1190 138 HOH HOH A . I 8 HOH 139 1191 139 HOH HOH A . I 8 HOH 140 1192 140 HOH HOH A . I 8 HOH 141 1193 141 HOH HOH A . I 8 HOH 142 1194 142 HOH HOH A . I 8 HOH 143 1195 143 HOH HOH A . I 8 HOH 144 1196 144 HOH HOH A . I 8 HOH 145 1197 145 HOH HOH A . I 8 HOH 146 1198 146 HOH HOH A . I 8 HOH 147 1199 147 HOH HOH A . I 8 HOH 148 1200 148 HOH HOH A . I 8 HOH 149 1201 149 HOH HOH A . I 8 HOH 150 1202 150 HOH HOH A . I 8 HOH 151 1203 151 HOH HOH A . I 8 HOH 152 1204 152 HOH HOH A . I 8 HOH 153 1205 153 HOH HOH A . I 8 HOH 154 1206 154 HOH HOH A . I 8 HOH 155 1207 155 HOH HOH A . I 8 HOH 156 1208 156 HOH HOH A . I 8 HOH 157 1209 157 HOH HOH A . I 8 HOH 158 1210 158 HOH HOH A . I 8 HOH 159 1211 159 HOH HOH A . I 8 HOH 160 1212 160 HOH HOH A . I 8 HOH 161 1213 161 HOH HOH A . I 8 HOH 162 1214 162 HOH HOH A . I 8 HOH 163 1215 163 HOH HOH A . I 8 HOH 164 1216 164 HOH HOH A . I 8 HOH 165 1217 165 HOH HOH A . I 8 HOH 166 1218 166 HOH HOH A . I 8 HOH 167 1219 167 HOH HOH A . I 8 HOH 168 1220 168 HOH HOH A . I 8 HOH 169 1221 169 HOH HOH A . I 8 HOH 170 1222 170 HOH HOH A . I 8 HOH 171 1223 171 HOH HOH A . I 8 HOH 172 1224 172 HOH HOH A . I 8 HOH 173 1225 173 HOH HOH A . I 8 HOH 174 1226 174 HOH HOH A . I 8 HOH 175 1227 175 HOH HOH A . I 8 HOH 176 1228 176 HOH HOH A . I 8 HOH 177 1229 177 HOH HOH A . I 8 HOH 178 1230 178 HOH HOH A . I 8 HOH 179 1231 179 HOH HOH A . I 8 HOH 180 1232 180 HOH HOH A . I 8 HOH 181 1233 181 HOH HOH A . I 8 HOH 182 1234 182 HOH HOH A . I 8 HOH 183 1235 183 HOH HOH A . I 8 HOH 184 1236 184 HOH HOH A . I 8 HOH 185 1237 185 HOH HOH A . I 8 HOH 186 1238 186 HOH HOH A . I 8 HOH 187 1239 187 HOH HOH A . I 8 HOH 188 1240 188 HOH HOH A . I 8 HOH 189 1241 189 HOH HOH A . I 8 HOH 190 1242 190 HOH HOH A . I 8 HOH 191 1243 191 HOH HOH A . I 8 HOH 192 1244 192 HOH HOH A . I 8 HOH 193 1245 193 HOH HOH A . I 8 HOH 194 1246 194 HOH HOH A . I 8 HOH 195 1247 195 HOH HOH A . I 8 HOH 196 1248 196 HOH HOH A . I 8 HOH 197 1249 197 HOH HOH A . I 8 HOH 198 1250 198 HOH HOH A . I 8 HOH 199 1251 199 HOH HOH A . I 8 HOH 200 1252 200 HOH HOH A . I 8 HOH 201 1253 201 HOH HOH A . I 8 HOH 202 1254 202 HOH HOH A . I 8 HOH 203 1255 203 HOH HOH A . I 8 HOH 204 1256 204 HOH HOH A . I 8 HOH 205 1257 205 HOH HOH A . I 8 HOH 206 1258 206 HOH HOH A . I 8 HOH 207 1259 207 HOH HOH A . I 8 HOH 208 1260 208 HOH HOH A . I 8 HOH 209 1261 209 HOH HOH A . I 8 HOH 210 1262 210 HOH HOH A . I 8 HOH 211 1263 211 HOH HOH A . I 8 HOH 212 1264 212 HOH HOH A . I 8 HOH 213 1265 213 HOH HOH A . I 8 HOH 214 1266 214 HOH HOH A . I 8 HOH 215 1267 215 HOH HOH A . I 8 HOH 216 1268 216 HOH HOH A . I 8 HOH 217 1269 217 HOH HOH A . I 8 HOH 218 1270 218 HOH HOH A . I 8 HOH 219 1271 219 HOH HOH A . I 8 HOH 220 1272 220 HOH HOH A . I 8 HOH 221 1273 221 HOH HOH A . I 8 HOH 222 1274 222 HOH HOH A . I 8 HOH 223 1275 223 HOH HOH A . I 8 HOH 224 1276 224 HOH HOH A . I 8 HOH 225 1277 225 HOH HOH A . I 8 HOH 226 1278 226 HOH HOH A . I 8 HOH 227 1279 227 HOH HOH A . I 8 HOH 228 1280 228 HOH HOH A . I 8 HOH 229 1281 229 HOH HOH A . I 8 HOH 230 1282 230 HOH HOH A . I 8 HOH 231 1283 231 HOH HOH A . I 8 HOH 232 1284 232 HOH HOH A . I 8 HOH 233 1285 233 HOH HOH A . I 8 HOH 234 1286 234 HOH HOH A . I 8 HOH 235 1287 235 HOH HOH A . I 8 HOH 236 1288 236 HOH HOH A . I 8 HOH 237 1289 237 HOH HOH A . I 8 HOH 238 1290 238 HOH HOH A . I 8 HOH 239 1291 239 HOH HOH A . I 8 HOH 240 1292 240 HOH HOH A . I 8 HOH 241 1293 241 HOH HOH A . I 8 HOH 242 1294 242 HOH HOH A . I 8 HOH 243 1295 243 HOH HOH A . I 8 HOH 244 1296 244 HOH HOH A . I 8 HOH 245 1297 245 HOH HOH A . I 8 HOH 246 1298 246 HOH HOH A . I 8 HOH 247 1299 247 HOH HOH A . I 8 HOH 248 1300 248 HOH HOH A . I 8 HOH 249 1301 249 HOH HOH A . I 8 HOH 250 1302 250 HOH HOH A . I 8 HOH 251 1303 251 HOH HOH A . I 8 HOH 252 1304 252 HOH HOH A . I 8 HOH 253 1305 253 HOH HOH A . I 8 HOH 254 1306 254 HOH HOH A . I 8 HOH 255 1307 255 HOH HOH A . I 8 HOH 256 1308 256 HOH HOH A . I 8 HOH 257 1309 257 HOH HOH A . I 8 HOH 258 1310 258 HOH HOH A . I 8 HOH 259 1311 259 HOH HOH A . I 8 HOH 260 1312 260 HOH HOH A . I 8 HOH 261 1313 261 HOH HOH A . I 8 HOH 262 1314 262 HOH HOH A . I 8 HOH 263 1315 263 HOH HOH A . I 8 HOH 264 1316 264 HOH HOH A . I 8 HOH 265 1317 265 HOH HOH A . I 8 HOH 266 1318 266 HOH HOH A . I 8 HOH 267 1319 267 HOH HOH A . I 8 HOH 268 1320 268 HOH HOH A . I 8 HOH 269 1321 269 HOH HOH A . I 8 HOH 270 1322 270 HOH HOH A . I 8 HOH 271 1323 271 HOH HOH A . I 8 HOH 272 1324 272 HOH HOH A . I 8 HOH 273 1325 273 HOH HOH A . I 8 HOH 274 1326 274 HOH HOH A . I 8 HOH 275 1327 275 HOH HOH A . I 8 HOH 276 1328 276 HOH HOH A . I 8 HOH 277 1329 277 HOH HOH A . I 8 HOH 278 1330 278 HOH HOH A . I 8 HOH 279 1331 279 HOH HOH A . I 8 HOH 280 1332 280 HOH HOH A . I 8 HOH 281 1333 281 HOH HOH A . I 8 HOH 282 1334 282 HOH HOH A . I 8 HOH 283 1335 283 HOH HOH A . I 8 HOH 284 1336 284 HOH HOH A . I 8 HOH 285 1337 285 HOH HOH A . I 8 HOH 286 1338 286 HOH HOH A . I 8 HOH 287 1339 287 HOH HOH A . I 8 HOH 288 1340 288 HOH HOH A . I 8 HOH 289 1341 289 HOH HOH A . I 8 HOH 290 1342 290 HOH HOH A . I 8 HOH 291 1343 291 HOH HOH A . I 8 HOH 292 1344 292 HOH HOH A . I 8 HOH 293 1345 293 HOH HOH A . I 8 HOH 294 1346 294 HOH HOH A . I 8 HOH 295 1347 295 HOH HOH A . I 8 HOH 296 1348 296 HOH HOH A . I 8 HOH 297 1349 297 HOH HOH A . I 8 HOH 298 1350 298 HOH HOH A . I 8 HOH 299 1351 299 HOH HOH A . I 8 HOH 300 1352 300 HOH HOH A . I 8 HOH 301 1353 301 HOH HOH A . I 8 HOH 302 1354 302 HOH HOH A . I 8 HOH 303 1355 303 HOH HOH A . I 8 HOH 304 1356 304 HOH HOH A . I 8 HOH 305 1357 305 HOH HOH A . I 8 HOH 306 1358 306 HOH HOH A . I 8 HOH 307 1359 307 HOH HOH A . I 8 HOH 308 1360 308 HOH HOH A . I 8 HOH 309 1361 309 HOH HOH A . I 8 HOH 310 1362 310 HOH HOH A . I 8 HOH 311 1363 311 HOH HOH A . I 8 HOH 312 1364 312 HOH HOH A . I 8 HOH 313 1365 313 HOH HOH A . I 8 HOH 314 1366 314 HOH HOH A . I 8 HOH 315 1367 315 HOH HOH A . I 8 HOH 316 1368 316 HOH HOH A . I 8 HOH 317 1369 317 HOH HOH A . I 8 HOH 318 1370 318 HOH HOH A . I 8 HOH 319 1371 319 HOH HOH A . I 8 HOH 320 1372 320 HOH HOH A . I 8 HOH 321 1373 321 HOH HOH A . I 8 HOH 322 1374 322 HOH HOH A . I 8 HOH 323 1375 323 HOH HOH A . I 8 HOH 324 1376 324 HOH HOH A . I 8 HOH 325 1377 325 HOH HOH A . I 8 HOH 326 1378 326 HOH HOH A . I 8 HOH 327 1379 327 HOH HOH A . I 8 HOH 328 1380 328 HOH HOH A . I 8 HOH 329 1381 329 HOH HOH A . I 8 HOH 330 1382 330 HOH HOH A . I 8 HOH 331 1383 331 HOH HOH A . I 8 HOH 332 1384 332 HOH HOH A . I 8 HOH 333 1385 333 HOH HOH A . I 8 HOH 334 1386 334 HOH HOH A . I 8 HOH 335 1387 335 HOH HOH A . I 8 HOH 336 1388 336 HOH HOH A . I 8 HOH 337 1389 337 HOH HOH A . I 8 HOH 338 1390 338 HOH HOH A . I 8 HOH 339 1391 339 HOH HOH A . I 8 HOH 340 1392 340 HOH HOH A . I 8 HOH 341 1393 341 HOH HOH A . I 8 HOH 342 1394 342 HOH HOH A . I 8 HOH 343 1395 343 HOH HOH A . I 8 HOH 344 1396 344 HOH HOH A . I 8 HOH 345 1397 345 HOH HOH A . I 8 HOH 346 1398 346 HOH HOH A . I 8 HOH 347 1399 347 HOH HOH A . I 8 HOH 348 1400 348 HOH HOH A . I 8 HOH 349 1401 349 HOH HOH A . I 8 HOH 350 1402 350 HOH HOH A . I 8 HOH 351 1403 351 HOH HOH A . I 8 HOH 352 1404 352 HOH HOH A . I 8 HOH 353 1405 353 HOH HOH A . I 8 HOH 354 1406 354 HOH HOH A . I 8 HOH 355 1407 355 HOH HOH A . I 8 HOH 356 1408 356 HOH HOH A . I 8 HOH 357 1409 357 HOH HOH A . I 8 HOH 358 1410 358 HOH HOH A . I 8 HOH 359 1411 359 HOH HOH A . I 8 HOH 360 1412 360 HOH HOH A . I 8 HOH 361 1413 361 HOH HOH A . I 8 HOH 362 1414 362 HOH HOH A . I 8 HOH 363 1415 363 HOH HOH A . I 8 HOH 364 1416 364 HOH HOH A . I 8 HOH 365 1417 365 HOH HOH A . I 8 HOH 366 1418 366 HOH HOH A . I 8 HOH 367 1419 367 HOH HOH A . I 8 HOH 368 1420 368 HOH HOH A . I 8 HOH 369 1421 369 HOH HOH A . I 8 HOH 370 1422 370 HOH HOH A . I 8 HOH 371 1423 371 HOH HOH A . I 8 HOH 372 1424 372 HOH HOH A . I 8 HOH 373 1425 373 HOH HOH A . I 8 HOH 374 1426 374 HOH HOH A . I 8 HOH 375 1427 375 HOH HOH A . I 8 HOH 376 1428 376 HOH HOH A . I 8 HOH 377 1429 377 HOH HOH A . I 8 HOH 378 1430 378 HOH HOH A . I 8 HOH 379 1431 379 HOH HOH A . I 8 HOH 380 1432 380 HOH HOH A . I 8 HOH 381 1433 381 HOH HOH A . I 8 HOH 382 1434 382 HOH HOH A . I 8 HOH 383 1435 383 HOH HOH A . I 8 HOH 384 1436 384 HOH HOH A . I 8 HOH 385 1437 385 HOH HOH A . I 8 HOH 386 1438 386 HOH HOH A . I 8 HOH 387 1439 387 HOH HOH A . I 8 HOH 388 1440 388 HOH HOH A . I 8 HOH 389 1441 389 HOH HOH A . I 8 HOH 390 1442 390 HOH HOH A . I 8 HOH 391 1443 391 HOH HOH A . I 8 HOH 392 1444 392 HOH HOH A . I 8 HOH 393 1445 393 HOH HOH A . I 8 HOH 394 1446 394 HOH HOH A . I 8 HOH 395 1447 395 HOH HOH A . I 8 HOH 396 1448 396 HOH HOH A . I 8 HOH 397 1449 397 HOH HOH A . I 8 HOH 398 1450 398 HOH HOH A . I 8 HOH 399 1451 399 HOH HOH A . I 8 HOH 400 1452 400 HOH HOH A . I 8 HOH 401 1453 401 HOH HOH A . I 8 HOH 402 1454 402 HOH HOH A . I 8 HOH 403 1455 403 HOH HOH A . I 8 HOH 404 1456 404 HOH HOH A . I 8 HOH 405 1457 405 HOH HOH A . I 8 HOH 406 1458 406 HOH HOH A . I 8 HOH 407 1459 407 HOH HOH A . I 8 HOH 408 1460 408 HOH HOH A . I 8 HOH 409 1461 409 HOH HOH A . I 8 HOH 410 1462 410 HOH HOH A . I 8 HOH 411 1463 411 HOH HOH A . I 8 HOH 412 1464 412 HOH HOH A . I 8 HOH 413 1465 413 HOH HOH A . I 8 HOH 414 1466 414 HOH HOH A . I 8 HOH 415 1467 415 HOH HOH A . I 8 HOH 416 1468 416 HOH HOH A . I 8 HOH 417 1469 417 HOH HOH A . I 8 HOH 418 1470 418 HOH HOH A . I 8 HOH 419 1471 419 HOH HOH A . I 8 HOH 420 1472 420 HOH HOH A . I 8 HOH 421 1473 421 HOH HOH A . I 8 HOH 422 1474 422 HOH HOH A . I 8 HOH 423 1475 423 HOH HOH A . I 8 HOH 424 1476 424 HOH HOH A . I 8 HOH 425 1477 425 HOH HOH A . I 8 HOH 426 1478 426 HOH HOH A . I 8 HOH 427 1479 427 HOH HOH A . I 8 HOH 428 1480 428 HOH HOH A . I 8 HOH 429 1481 429 HOH HOH A . I 8 HOH 430 1482 430 HOH HOH A . I 8 HOH 431 1483 431 HOH HOH A . I 8 HOH 432 1484 432 HOH HOH A . I 8 HOH 433 1485 433 HOH HOH A . I 8 HOH 434 1486 434 HOH HOH A . I 8 HOH 435 1487 435 HOH HOH A . I 8 HOH 436 1488 436 HOH HOH A . I 8 HOH 437 1489 437 HOH HOH A . I 8 HOH 438 1490 438 HOH HOH A . I 8 HOH 439 1491 439 HOH HOH A . I 8 HOH 440 1492 440 HOH HOH A . I 8 HOH 441 1493 441 HOH HOH A . I 8 HOH 442 1494 442 HOH HOH A . I 8 HOH 443 1495 443 HOH HOH A . I 8 HOH 444 1496 444 HOH HOH A . I 8 HOH 445 1497 445 HOH HOH A . I 8 HOH 446 1498 446 HOH HOH A . I 8 HOH 447 1499 447 HOH HOH A . I 8 HOH 448 1500 448 HOH HOH A . I 8 HOH 449 1501 449 HOH HOH A . I 8 HOH 450 1502 450 HOH HOH A . I 8 HOH 451 1503 451 HOH HOH A . I 8 HOH 452 1504 452 HOH HOH A . I 8 HOH 453 1505 453 HOH HOH A . I 8 HOH 454 1506 454 HOH HOH A . I 8 HOH 455 1507 455 HOH HOH A . I 8 HOH 456 1508 456 HOH HOH A . I 8 HOH 457 1509 457 HOH HOH A . I 8 HOH 458 1510 458 HOH HOH A . I 8 HOH 459 1511 459 HOH HOH A . I 8 HOH 460 1512 460 HOH HOH A . I 8 HOH 461 1513 461 HOH HOH A . I 8 HOH 462 1514 462 HOH HOH A . I 8 HOH 463 1515 463 HOH HOH A . I 8 HOH 464 1516 464 HOH HOH A . I 8 HOH 465 1517 465 HOH HOH A . I 8 HOH 466 1518 466 HOH HOH A . I 8 HOH 467 1519 467 HOH HOH A . I 8 HOH 468 1520 468 HOH HOH A . I 8 HOH 469 1521 469 HOH HOH A . I 8 HOH 470 1522 470 HOH HOH A . I 8 HOH 471 1523 471 HOH HOH A . I 8 HOH 472 1524 472 HOH HOH A . I 8 HOH 473 1525 473 HOH HOH A . I 8 HOH 474 1526 474 HOH HOH A . I 8 HOH 475 1527 475 HOH HOH A . I 8 HOH 476 1528 476 HOH HOH A . I 8 HOH 477 1529 477 HOH HOH A . I 8 HOH 478 1530 478 HOH HOH A . I 8 HOH 479 1531 479 HOH HOH A . I 8 HOH 480 1532 480 HOH HOH A . I 8 HOH 481 1533 481 HOH HOH A . I 8 HOH 482 1534 482 HOH HOH A . I 8 HOH 483 1535 483 HOH HOH A . I 8 HOH 484 1536 484 HOH HOH A . I 8 HOH 485 1537 485 HOH HOH A . I 8 HOH 486 1538 486 HOH HOH A . I 8 HOH 487 1539 487 HOH HOH A . I 8 HOH 488 1540 488 HOH HOH A . I 8 HOH 489 1541 489 HOH HOH A . I 8 HOH 490 1542 490 HOH HOH A . I 8 HOH 491 1543 491 HOH HOH A . I 8 HOH 492 1544 492 HOH HOH A . I 8 HOH 493 1545 493 HOH HOH A . I 8 HOH 494 1546 494 HOH HOH A . I 8 HOH 495 1547 495 HOH HOH A . I 8 HOH 496 1548 496 HOH HOH A . I 8 HOH 497 1549 497 HOH HOH A . I 8 HOH 498 1550 498 HOH HOH A . I 8 HOH 499 1551 499 HOH HOH A . I 8 HOH 500 1552 500 HOH HOH A . I 8 HOH 501 1553 501 HOH HOH A . I 8 HOH 502 1554 502 HOH HOH A . I 8 HOH 503 1555 503 HOH HOH A . I 8 HOH 504 1556 504 HOH HOH A . I 8 HOH 505 1557 505 HOH HOH A . I 8 HOH 506 1558 506 HOH HOH A . I 8 HOH 507 1559 507 HOH HOH A . I 8 HOH 508 1560 508 HOH HOH A . I 8 HOH 509 1561 509 HOH HOH A . I 8 HOH 510 1562 510 HOH HOH A . I 8 HOH 511 1563 511 HOH HOH A . I 8 HOH 512 1564 512 HOH HOH A . I 8 HOH 513 1565 513 HOH HOH A . I 8 HOH 514 1566 514 HOH HOH A . I 8 HOH 515 1567 515 HOH HOH A . I 8 HOH 516 1568 516 HOH HOH A . I 8 HOH 517 1569 517 HOH HOH A . I 8 HOH 518 1570 518 HOH HOH A . I 8 HOH 519 1571 519 HOH HOH A . I 8 HOH 520 1572 520 HOH HOH A . I 8 HOH 521 1573 521 HOH HOH A . I 8 HOH 522 1574 522 HOH HOH A . I 8 HOH 523 1575 523 HOH HOH A . I 8 HOH 524 1576 524 HOH HOH A . I 8 HOH 525 1577 525 HOH HOH A . I 8 HOH 526 1578 526 HOH HOH A . I 8 HOH 527 1579 527 HOH HOH A . I 8 HOH 528 1580 528 HOH HOH A . I 8 HOH 529 1581 529 HOH HOH A . I 8 HOH 530 1582 530 HOH HOH A . I 8 HOH 531 1583 531 HOH HOH A . I 8 HOH 532 1584 532 HOH HOH A . I 8 HOH 533 1585 533 HOH HOH A . I 8 HOH 534 1586 534 HOH HOH A . I 8 HOH 535 1587 535 HOH HOH A . I 8 HOH 536 1588 536 HOH HOH A . I 8 HOH 537 1589 537 HOH HOH A . I 8 HOH 538 1590 538 HOH HOH A . I 8 HOH 539 1591 539 HOH HOH A . I 8 HOH 540 1592 540 HOH HOH A . I 8 HOH 541 1593 541 HOH HOH A . I 8 HOH 542 1594 542 HOH HOH A . I 8 HOH 543 1595 543 HOH HOH A . I 8 HOH 544 1596 544 HOH HOH A . I 8 HOH 545 1597 545 HOH HOH A . I 8 HOH 546 1598 546 HOH HOH A . I 8 HOH 547 1599 547 HOH HOH A . I 8 HOH 548 1600 548 HOH HOH A . I 8 HOH 549 1601 549 HOH HOH A . I 8 HOH 550 1602 550 HOH HOH A . I 8 HOH 551 1603 551 HOH HOH A . I 8 HOH 552 1604 552 HOH HOH A . I 8 HOH 553 1605 553 HOH HOH A . I 8 HOH 554 1606 554 HOH HOH A . I 8 HOH 555 1607 555 HOH HOH A . I 8 HOH 556 1608 556 HOH HOH A . I 8 HOH 557 1609 557 HOH HOH A . I 8 HOH 558 1610 558 HOH HOH A . I 8 HOH 559 1611 559 HOH HOH A . I 8 HOH 560 1612 560 HOH HOH A . I 8 HOH 561 1613 561 HOH HOH A . I 8 HOH 562 1614 562 HOH HOH A . I 8 HOH 563 1615 563 HOH HOH A . I 8 HOH 564 1616 564 HOH HOH A . I 8 HOH 565 1617 565 HOH HOH A . I 8 HOH 566 1618 566 HOH HOH A . I 8 HOH 567 1619 567 HOH HOH A . I 8 HOH 568 1620 568 HOH HOH A . I 8 HOH 569 1621 569 HOH HOH A . I 8 HOH 570 1622 570 HOH HOH A . I 8 HOH 571 1623 571 HOH HOH A . I 8 HOH 572 1624 572 HOH HOH A . I 8 HOH 573 1625 573 HOH HOH A . I 8 HOH 574 1626 574 HOH HOH A . I 8 HOH 575 1627 575 HOH HOH A . I 8 HOH 576 1628 576 HOH HOH A . I 8 HOH 577 1629 577 HOH HOH A . I 8 HOH 578 1630 578 HOH HOH A . I 8 HOH 579 1631 579 HOH HOH A . I 8 HOH 580 1632 580 HOH HOH A . I 8 HOH 581 1633 581 HOH HOH A . I 8 HOH 582 1634 582 HOH HOH A . I 8 HOH 583 1635 583 HOH HOH A . I 8 HOH 584 1636 584 HOH HOH A . I 8 HOH 585 1637 585 HOH HOH A . I 8 HOH 586 1638 586 HOH HOH A . I 8 HOH 587 1639 587 HOH HOH A . I 8 HOH 588 1640 588 HOH HOH A . I 8 HOH 589 1641 589 HOH HOH A . I 8 HOH 590 1642 590 HOH HOH A . I 8 HOH 591 1643 591 HOH HOH A . I 8 HOH 592 1644 592 HOH HOH A . I 8 HOH 593 1645 593 HOH HOH A . I 8 HOH 594 1646 594 HOH HOH A . I 8 HOH 595 1647 595 HOH HOH A . I 8 HOH 596 1648 596 HOH HOH A . I 8 HOH 597 1649 597 HOH HOH A . I 8 HOH 598 1650 598 HOH HOH A . I 8 HOH 599 1651 599 HOH HOH A . I 8 HOH 600 1652 600 HOH HOH A . I 8 HOH 601 1653 601 HOH HOH A . I 8 HOH 602 1654 602 HOH HOH A . I 8 HOH 603 1655 603 HOH HOH A . I 8 HOH 604 1656 604 HOH HOH A . I 8 HOH 605 1657 605 HOH HOH A . I 8 HOH 606 1658 606 HOH HOH A . I 8 HOH 607 1659 607 HOH HOH A . I 8 HOH 608 1660 608 HOH HOH A . I 8 HOH 609 1661 609 HOH HOH A . I 8 HOH 610 1662 610 HOH HOH A . I 8 HOH 611 1663 611 HOH HOH A . I 8 HOH 612 1664 612 HOH HOH A . I 8 HOH 613 1665 613 HOH HOH A . I 8 HOH 614 1666 614 HOH HOH A . I 8 HOH 615 1667 615 HOH HOH A . I 8 HOH 616 1668 616 HOH HOH A . I 8 HOH 617 1669 617 HOH HOH A . I 8 HOH 618 1670 618 HOH HOH A . I 8 HOH 619 1671 619 HOH HOH A . I 8 HOH 620 1672 620 HOH HOH A . I 8 HOH 621 1673 621 HOH HOH A . I 8 HOH 622 1674 622 HOH HOH A . I 8 HOH 623 1675 623 HOH HOH A . I 8 HOH 624 1676 624 HOH HOH A . I 8 HOH 625 1677 625 HOH HOH A . I 8 HOH 626 1678 626 HOH HOH A . I 8 HOH 627 1679 627 HOH HOH A . I 8 HOH 628 1680 628 HOH HOH A . I 8 HOH 629 1681 629 HOH HOH A . I 8 HOH 630 1682 630 HOH HOH A . I 8 HOH 631 1683 631 HOH HOH A . I 8 HOH 632 1684 632 HOH HOH A . I 8 HOH 633 1685 633 HOH HOH A . I 8 HOH 634 1686 634 HOH HOH A . I 8 HOH 635 1687 635 HOH HOH A . I 8 HOH 636 1688 636 HOH HOH A . I 8 HOH 637 1689 637 HOH HOH A . I 8 HOH 638 1690 638 HOH HOH A . I 8 HOH 639 1691 639 HOH HOH A . I 8 HOH 640 1692 640 HOH HOH A . I 8 HOH 641 1693 641 HOH HOH A . I 8 HOH 642 1694 642 HOH HOH A . I 8 HOH 643 1695 643 HOH HOH A . I 8 HOH 644 1696 644 HOH HOH A . I 8 HOH 645 1697 645 HOH HOH A . I 8 HOH 646 1698 646 HOH HOH A . I 8 HOH 647 1699 647 HOH HOH A . I 8 HOH 648 1700 648 HOH HOH A . I 8 HOH 649 1701 649 HOH HOH A . I 8 HOH 650 1702 650 HOH HOH A . I 8 HOH 651 1703 651 HOH HOH A . I 8 HOH 652 1704 652 HOH HOH A . I 8 HOH 653 1705 653 HOH HOH A . I 8 HOH 654 1706 654 HOH HOH A . I 8 HOH 655 1707 655 HOH HOH A . I 8 HOH 656 1708 656 HOH HOH A . I 8 HOH 657 1709 657 HOH HOH A . I 8 HOH 658 1710 658 HOH HOH A . I 8 HOH 659 1711 659 HOH HOH A . I 8 HOH 660 1712 660 HOH HOH A . I 8 HOH 661 1713 661 HOH HOH A . I 8 HOH 662 1714 662 HOH HOH A . I 8 HOH 663 1715 663 HOH HOH A . I 8 HOH 664 1716 664 HOH HOH A . I 8 HOH 665 1717 665 HOH HOH A . I 8 HOH 666 1718 666 HOH HOH A . I 8 HOH 667 1719 667 HOH HOH A . I 8 HOH 668 1720 668 HOH HOH A . I 8 HOH 669 1721 669 HOH HOH A . I 8 HOH 670 1722 670 HOH HOH A . I 8 HOH 671 1723 671 HOH HOH A . I 8 HOH 672 1724 672 HOH HOH A . I 8 HOH 673 1725 673 HOH HOH A . I 8 HOH 674 1726 674 HOH HOH A . I 8 HOH 675 1727 675 HOH HOH A . I 8 HOH 676 1728 676 HOH HOH A . I 8 HOH 677 1729 677 HOH HOH A . I 8 HOH 678 1730 678 HOH HOH A . I 8 HOH 679 1731 679 HOH HOH A . I 8 HOH 680 1732 680 HOH HOH A . I 8 HOH 681 1733 681 HOH HOH A . I 8 HOH 682 1734 682 HOH HOH A . I 8 HOH 683 1735 683 HOH HOH A . I 8 HOH 684 1736 684 HOH HOH A . I 8 HOH 685 1737 685 HOH HOH A . I 8 HOH 686 1738 686 HOH HOH A . I 8 HOH 687 1739 687 HOH HOH A . I 8 HOH 688 1740 688 HOH HOH A . I 8 HOH 689 1741 689 HOH HOH A . I 8 HOH 690 1742 690 HOH HOH A . I 8 HOH 691 1743 691 HOH HOH A . I 8 HOH 692 1744 692 HOH HOH A . I 8 HOH 693 1745 693 HOH HOH A . I 8 HOH 694 1746 694 HOH HOH A . I 8 HOH 695 1747 695 HOH HOH A . I 8 HOH 696 1748 696 HOH HOH A . I 8 HOH 697 1749 697 HOH HOH A . I 8 HOH 698 1750 698 HOH HOH A . I 8 HOH 699 1751 699 HOH HOH A . I 8 HOH 700 1752 700 HOH HOH A . I 8 HOH 701 1753 701 HOH HOH A . I 8 HOH 702 1754 702 HOH HOH A . I 8 HOH 703 1755 703 HOH HOH A . I 8 HOH 704 1756 704 HOH HOH A . I 8 HOH 705 1757 705 HOH HOH A . I 8 HOH 706 1758 706 HOH HOH A . I 8 HOH 707 1759 707 HOH HOH A . I 8 HOH 708 1760 708 HOH HOH A . I 8 HOH 709 1761 709 HOH HOH A . I 8 HOH 710 1762 710 HOH HOH A . I 8 HOH 711 1763 711 HOH HOH A . I 8 HOH 712 1764 712 HOH HOH A . I 8 HOH 713 1765 713 HOH HOH A . I 8 HOH 714 1766 714 HOH HOH A . I 8 HOH 715 1767 715 HOH HOH A . I 8 HOH 716 1768 716 HOH HOH A . I 8 HOH 717 1769 717 HOH HOH A . I 8 HOH 718 1770 718 HOH HOH A . I 8 HOH 719 1771 719 HOH HOH A . I 8 HOH 720 1772 720 HOH HOH A . I 8 HOH 721 1773 721 HOH HOH A . I 8 HOH 722 1774 722 HOH HOH A . I 8 HOH 723 1775 723 HOH HOH A . I 8 HOH 724 1776 724 HOH HOH A . I 8 HOH 725 1777 725 HOH HOH A . I 8 HOH 726 1778 726 HOH HOH A . I 8 HOH 727 1779 727 HOH HOH A . I 8 HOH 728 1780 728 HOH HOH A . I 8 HOH 729 1781 729 HOH HOH A . I 8 HOH 730 1782 730 HOH HOH A . I 8 HOH 731 1783 731 HOH HOH A . I 8 HOH 732 1784 732 HOH HOH A . I 8 HOH 733 1785 733 HOH HOH A . I 8 HOH 734 1786 734 HOH HOH A . I 8 HOH 735 1787 735 HOH HOH A . I 8 HOH 736 1788 736 HOH HOH A . I 8 HOH 737 1789 737 HOH HOH A . I 8 HOH 738 1790 738 HOH HOH A . I 8 HOH 739 1791 739 HOH HOH A . I 8 HOH 740 1792 740 HOH HOH A . I 8 HOH 741 1793 741 HOH HOH A . I 8 HOH 742 1794 742 HOH HOH A . I 8 HOH 743 1795 743 HOH HOH A . I 8 HOH 744 1796 744 HOH HOH A . I 8 HOH 745 1797 745 HOH HOH A . I 8 HOH 746 1798 746 HOH HOH A . I 8 HOH 747 1799 747 HOH HOH A . I 8 HOH 748 1800 748 HOH HOH A . I 8 HOH 749 1801 749 HOH HOH A . I 8 HOH 750 1802 750 HOH HOH A . I 8 HOH 751 1803 751 HOH HOH A . I 8 HOH 752 1804 752 HOH HOH A . I 8 HOH 753 1805 753 HOH HOH A . I 8 HOH 754 1806 754 HOH HOH A . I 8 HOH 755 1807 755 HOH HOH A . I 8 HOH 756 1808 756 HOH HOH A . I 8 HOH 757 1809 757 HOH HOH A . I 8 HOH 758 1810 758 HOH HOH A . I 8 HOH 759 1811 759 HOH HOH A . I 8 HOH 760 1812 760 HOH HOH A . I 8 HOH 761 1813 761 HOH HOH A . I 8 HOH 762 1814 762 HOH HOH A . I 8 HOH 763 1815 763 HOH HOH A . I 8 HOH 764 1816 764 HOH HOH A . I 8 HOH 765 1817 765 HOH HOH A . I 8 HOH 766 1818 766 HOH HOH A . I 8 HOH 767 1819 767 HOH HOH A . I 8 HOH 768 1820 768 HOH HOH A . I 8 HOH 769 1821 769 HOH HOH A . I 8 HOH 770 1822 770 HOH HOH A . I 8 HOH 771 1823 771 HOH HOH A . I 8 HOH 772 1824 772 HOH HOH A . I 8 HOH 773 1825 773 HOH HOH A . I 8 HOH 774 1826 774 HOH HOH A . I 8 HOH 775 1827 775 HOH HOH A . I 8 HOH 776 1828 776 HOH HOH A . I 8 HOH 777 1829 777 HOH HOH A . I 8 HOH 778 1830 778 HOH HOH A . I 8 HOH 779 1831 779 HOH HOH A . I 8 HOH 780 1832 780 HOH HOH A . I 8 HOH 781 1833 781 HOH HOH A . I 8 HOH 782 1834 782 HOH HOH A . I 8 HOH 783 1835 783 HOH HOH A . I 8 HOH 784 1836 784 HOH HOH A . I 8 HOH 785 1837 785 HOH HOH A . I 8 HOH 786 1838 786 HOH HOH A . I 8 HOH 787 1839 787 HOH HOH A . I 8 HOH 788 1840 788 HOH HOH A . I 8 HOH 789 1841 789 HOH HOH A . I 8 HOH 790 1842 790 HOH HOH A . I 8 HOH 791 1843 791 HOH HOH A . I 8 HOH 792 1844 792 HOH HOH A . I 8 HOH 793 1845 793 HOH HOH A . I 8 HOH 794 1846 794 HOH HOH A . I 8 HOH 795 1847 795 HOH HOH A . I 8 HOH 796 1848 796 HOH HOH A . I 8 HOH 797 1849 797 HOH HOH A . I 8 HOH 798 1850 798 HOH HOH A . I 8 HOH 799 1851 799 HOH HOH A . I 8 HOH 800 1852 800 HOH HOH A . I 8 HOH 801 1853 801 HOH HOH A . I 8 HOH 802 1854 802 HOH HOH A . I 8 HOH 803 1855 803 HOH HOH A . I 8 HOH 804 1856 804 HOH HOH A . I 8 HOH 805 1857 805 HOH HOH A . I 8 HOH 806 1858 806 HOH HOH A . I 8 HOH 807 1859 807 HOH HOH A . I 8 HOH 808 1860 808 HOH HOH A . I 8 HOH 809 1861 809 HOH HOH A . I 8 HOH 810 1862 810 HOH HOH A . I 8 HOH 811 1863 811 HOH HOH A . I 8 HOH 812 1864 812 HOH HOH A . I 8 HOH 813 1865 813 HOH HOH A . I 8 HOH 814 1866 814 HOH HOH A . I 8 HOH 815 1867 815 HOH HOH A . I 8 HOH 816 1868 816 HOH HOH A . I 8 HOH 817 1869 817 HOH HOH A . I 8 HOH 818 1870 818 HOH HOH A . I 8 HOH 819 1871 819 HOH HOH A . I 8 HOH 820 1872 820 HOH HOH A . I 8 HOH 821 1873 821 HOH HOH A . I 8 HOH 822 1874 822 HOH HOH A . I 8 HOH 823 1875 823 HOH HOH A . I 8 HOH 824 1876 824 HOH HOH A . I 8 HOH 825 1877 825 HOH HOH A . I 8 HOH 826 1878 826 HOH HOH A . I 8 HOH 827 1879 827 HOH HOH A . I 8 HOH 828 1880 828 HOH HOH A . I 8 HOH 829 1881 829 HOH HOH A . I 8 HOH 830 1882 830 HOH HOH A . I 8 HOH 831 1883 831 HOH HOH A . I 8 HOH 832 1884 833 HOH HOH A . I 8 HOH 833 1885 834 HOH HOH A . I 8 HOH 834 1886 835 HOH HOH A . I 8 HOH 835 1887 836 HOH HOH A . I 8 HOH 836 1888 837 HOH HOH A . I 8 HOH 837 1889 838 HOH HOH A . I 8 HOH 838 1890 839 HOH HOH A . I 8 HOH 839 1891 840 HOH HOH A . I 8 HOH 840 1892 841 HOH HOH A . I 8 HOH 841 1893 842 HOH HOH A . I 8 HOH 842 1894 843 HOH HOH A . I 8 HOH 843 1895 844 HOH HOH A . I 8 HOH 844 1896 845 HOH HOH A . I 8 HOH 845 1897 846 HOH HOH A . I 8 HOH 846 1898 847 HOH HOH A . I 8 HOH 847 1899 848 HOH HOH A . I 8 HOH 848 1900 849 HOH HOH A . I 8 HOH 849 1901 850 HOH HOH A . I 8 HOH 850 1902 851 HOH HOH A . I 8 HOH 851 1903 852 HOH HOH A . I 8 HOH 852 1904 853 HOH HOH A . I 8 HOH 853 1905 854 HOH HOH A . I 8 HOH 854 1906 855 HOH HOH A . I 8 HOH 855 1907 856 HOH HOH A . I 8 HOH 856 1908 857 HOH HOH A . I 8 HOH 857 1909 858 HOH HOH A . I 8 HOH 858 1910 859 HOH HOH A . I 8 HOH 859 1911 860 HOH HOH A . I 8 HOH 860 1912 861 HOH HOH A . I 8 HOH 861 1913 862 HOH HOH A . I 8 HOH 862 1914 863 HOH HOH A . I 8 HOH 863 1915 864 HOH HOH A . I 8 HOH 864 1916 865 HOH HOH A . I 8 HOH 865 1917 866 HOH HOH A . I 8 HOH 866 1918 867 HOH HOH A . I 8 HOH 867 1919 868 HOH HOH A . I 8 HOH 868 1920 869 HOH HOH A . I 8 HOH 869 1921 870 HOH HOH A . I 8 HOH 870 1922 871 HOH HOH A . I 8 HOH 871 1923 872 HOH HOH A . I 8 HOH 872 1924 873 HOH HOH A . I 8 HOH 873 1925 874 HOH HOH A . I 8 HOH 874 1926 875 HOH HOH A . I 8 HOH 875 1927 876 HOH HOH A . I 8 HOH 876 1928 877 HOH HOH A . I 8 HOH 877 1929 878 HOH HOH A . I 8 HOH 878 1930 879 HOH HOH A . I 8 HOH 879 1931 880 HOH HOH A . I 8 HOH 880 1932 881 HOH HOH A . I 8 HOH 881 1933 882 HOH HOH A . I 8 HOH 882 1934 883 HOH HOH A . I 8 HOH 883 1935 884 HOH HOH A . I 8 HOH 884 1936 885 HOH HOH A . I 8 HOH 885 1937 886 HOH HOH A . I 8 HOH 886 1938 887 HOH HOH A . I 8 HOH 887 1939 888 HOH HOH A . I 8 HOH 888 1940 889 HOH HOH A . I 8 HOH 889 1941 890 HOH HOH A . I 8 HOH 890 1942 891 HOH HOH A . I 8 HOH 891 1943 892 HOH HOH A . I 8 HOH 892 1944 893 HOH HOH A . I 8 HOH 893 1945 894 HOH HOH A . I 8 HOH 894 1946 895 HOH HOH A . I 8 HOH 895 1947 896 HOH HOH A . I 8 HOH 896 1948 897 HOH HOH A . I 8 HOH 897 1949 898 HOH HOH A . I 8 HOH 898 1950 899 HOH HOH A . I 8 HOH 899 1951 900 HOH HOH A . I 8 HOH 900 1952 901 HOH HOH A . I 8 HOH 901 1953 902 HOH HOH A . I 8 HOH 902 1954 903 HOH HOH A . I 8 HOH 903 1955 904 HOH HOH A . I 8 HOH 904 1956 905 HOH HOH A . I 8 HOH 905 1957 906 HOH HOH A . I 8 HOH 906 1958 907 HOH HOH A . I 8 HOH 907 1959 908 HOH HOH A . I 8 HOH 908 1960 909 HOH HOH A . I 8 HOH 909 1961 910 HOH HOH A . I 8 HOH 910 1962 911 HOH HOH A . I 8 HOH 911 1963 912 HOH HOH A . I 8 HOH 912 1964 913 HOH HOH A . I 8 HOH 913 1965 914 HOH HOH A . I 8 HOH 914 1966 915 HOH HOH A . I 8 HOH 915 1967 916 HOH HOH A . I 8 HOH 916 1968 917 HOH HOH A . I 8 HOH 917 1969 918 HOH HOH A . I 8 HOH 918 1970 919 HOH HOH A . I 8 HOH 919 1971 920 HOH HOH A . I 8 HOH 920 1972 921 HOH HOH A . I 8 HOH 921 1973 922 HOH HOH A . I 8 HOH 922 1974 923 HOH HOH A . I 8 HOH 923 1975 924 HOH HOH A . I 8 HOH 924 1976 925 HOH HOH A . I 8 HOH 925 1977 926 HOH HOH A . I 8 HOH 926 1978 927 HOH HOH A . I 8 HOH 927 1979 928 HOH HOH A . I 8 HOH 928 1980 929 HOH HOH A . I 8 HOH 929 1981 930 HOH HOH A . I 8 HOH 930 1982 931 HOH HOH A . I 8 HOH 931 1983 932 HOH HOH A . I 8 HOH 932 1984 933 HOH HOH A . I 8 HOH 933 1985 934 HOH HOH A . I 8 HOH 934 1986 935 HOH HOH A . I 8 HOH 935 1987 936 HOH HOH A . I 8 HOH 936 1988 937 HOH HOH A . I 8 HOH 937 1989 938 HOH HOH A . I 8 HOH 938 1990 939 HOH HOH A . I 8 HOH 939 1991 940 HOH HOH A . I 8 HOH 940 1992 941 HOH HOH A . I 8 HOH 941 1993 942 HOH HOH A . I 8 HOH 942 1994 943 HOH HOH A . I 8 HOH 943 1995 944 HOH HOH A . I 8 HOH 944 1996 945 HOH HOH A . I 8 HOH 945 1997 946 HOH HOH A . I 8 HOH 946 1998 947 HOH HOH A . I 8 HOH 947 1999 948 HOH HOH A . I 8 HOH 948 2000 949 HOH HOH A . I 8 HOH 949 2001 950 HOH HOH A . I 8 HOH 950 2002 951 HOH HOH A . I 8 HOH 951 2003 952 HOH HOH A . I 8 HOH 952 2004 953 HOH HOH A . I 8 HOH 953 2005 954 HOH HOH A . I 8 HOH 954 2006 955 HOH HOH A . I 8 HOH 955 2007 956 HOH HOH A . I 8 HOH 956 2008 957 HOH HOH A . I 8 HOH 957 2009 958 HOH HOH A . I 8 HOH 958 2010 959 HOH HOH A . I 8 HOH 959 2011 960 HOH HOH A . I 8 HOH 960 2012 961 HOH HOH A . I 8 HOH 961 2013 962 HOH HOH A . I 8 HOH 962 2014 963 HOH HOH A . I 8 HOH 963 2015 964 HOH HOH A . I 8 HOH 964 2016 965 HOH HOH A . I 8 HOH 965 2017 966 HOH HOH A . I 8 HOH 966 2018 967 HOH HOH A . I 8 HOH 967 2019 968 HOH HOH A . I 8 HOH 968 2020 969 HOH HOH A . I 8 HOH 969 2021 970 HOH HOH A . I 8 HOH 970 2022 971 HOH HOH A . I 8 HOH 971 2023 972 HOH HOH A . I 8 HOH 972 2024 973 HOH HOH A . I 8 HOH 973 2025 974 HOH HOH A . I 8 HOH 974 2026 975 HOH HOH A . I 8 HOH 975 2027 976 HOH HOH A . I 8 HOH 976 2028 977 HOH HOH A . I 8 HOH 977 2029 978 HOH HOH A . I 8 HOH 978 2030 979 HOH HOH A . I 8 HOH 979 2031 980 HOH HOH A . I 8 HOH 980 2032 981 HOH HOH A . I 8 HOH 981 2033 982 HOH HOH A . I 8 HOH 982 2034 983 HOH HOH A . I 8 HOH 983 2035 984 HOH HOH A . I 8 HOH 984 2036 985 HOH HOH A . I 8 HOH 985 2037 986 HOH HOH A . I 8 HOH 986 2038 987 HOH HOH A . I 8 HOH 987 2039 988 HOH HOH A . I 8 HOH 988 2040 989 HOH HOH A . I 8 HOH 989 2041 990 HOH HOH A . I 8 HOH 990 2042 991 HOH HOH A . I 8 HOH 991 2043 992 HOH HOH A . I 8 HOH 992 2044 993 HOH HOH A . I 8 HOH 993 2045 994 HOH HOH A . I 8 HOH 994 2046 995 HOH HOH A . I 8 HOH 995 2047 996 HOH HOH A . I 8 HOH 996 2048 997 HOH HOH A . I 8 HOH 997 2049 998 HOH HOH A . I 8 HOH 998 2050 999 HOH HOH A . I 8 HOH 999 2051 1000 HOH HOH A . I 8 HOH 1000 2052 1001 HOH HOH A . I 8 HOH 1001 2053 1002 HOH HOH A . I 8 HOH 1002 2054 1003 HOH HOH A . I 8 HOH 1003 2055 1004 HOH HOH A . I 8 HOH 1004 2056 1005 HOH HOH A . I 8 HOH 1005 2057 1006 HOH HOH A . I 8 HOH 1006 2058 1007 HOH HOH A . I 8 HOH 1007 2059 1008 HOH HOH A . I 8 HOH 1008 2060 1009 HOH HOH A . I 8 HOH 1009 2061 1010 HOH HOH A . I 8 HOH 1010 2062 1011 HOH HOH A . I 8 HOH 1011 2063 1012 HOH HOH A . I 8 HOH 1012 2064 1013 HOH HOH A . I 8 HOH 1013 2065 1014 HOH HOH A . I 8 HOH 1014 2066 1015 HOH HOH A . I 8 HOH 1015 2067 1016 HOH HOH A . I 8 HOH 1016 2068 1017 HOH HOH A . I 8 HOH 1017 2069 1018 HOH HOH A . I 8 HOH 1018 2070 1019 HOH HOH A . I 8 HOH 1019 2071 1020 HOH HOH A . I 8 HOH 1020 2072 1021 HOH HOH A . I 8 HOH 1021 2073 1022 HOH HOH A . I 8 HOH 1022 2074 1023 HOH HOH A . I 8 HOH 1023 2075 1024 HOH HOH A . I 8 HOH 1024 2076 1025 HOH HOH A . I 8 HOH 1025 2077 1026 HOH HOH A . I 8 HOH 1026 2078 1027 HOH HOH A . I 8 HOH 1027 2079 1028 HOH HOH A . I 8 HOH 1028 2080 1029 HOH HOH A . I 8 HOH 1029 2081 1030 HOH HOH A . I 8 HOH 1030 2082 1031 HOH HOH A . I 8 HOH 1031 2083 1032 HOH HOH A . I 8 HOH 1032 2084 1033 HOH HOH A . I 8 HOH 1033 2085 1034 HOH HOH A . I 8 HOH 1034 2086 1035 HOH HOH A . I 8 HOH 1035 2087 1036 HOH HOH A . I 8 HOH 1036 2088 1037 HOH HOH A . I 8 HOH 1037 2089 1038 HOH HOH A . I 8 HOH 1038 2090 1039 HOH HOH A . I 8 HOH 1039 2091 1040 HOH HOH A . I 8 HOH 1040 2092 1041 HOH HOH A . I 8 HOH 1041 2093 1042 HOH HOH A . I 8 HOH 1042 2094 1043 HOH HOH A . I 8 HOH 1043 2095 1044 HOH HOH A . I 8 HOH 1044 2096 1045 HOH HOH A . I 8 HOH 1045 2097 1046 HOH HOH A . I 8 HOH 1046 2098 1047 HOH HOH A . I 8 HOH 1047 2099 1048 HOH HOH A . I 8 HOH 1048 2100 1049 HOH HOH A . I 8 HOH 1049 2101 1050 HOH HOH A . I 8 HOH 1050 2102 1051 HOH HOH A . I 8 HOH 1051 2103 1052 HOH HOH A . I 8 HOH 1052 2104 1053 HOH HOH A . I 8 HOH 1053 2105 1054 HOH HOH A . I 8 HOH 1054 2106 1055 HOH HOH A . I 8 HOH 1055 2107 1056 HOH HOH A . I 8 HOH 1056 2108 1057 HOH HOH A . I 8 HOH 1057 2109 1058 HOH HOH A . I 8 HOH 1058 2110 1059 HOH HOH A . I 8 HOH 1059 2111 1060 HOH HOH A . I 8 HOH 1060 2112 1061 HOH HOH A . I 8 HOH 1061 2113 1062 HOH HOH A . I 8 HOH 1062 2114 1063 HOH HOH A . I 8 HOH 1063 2115 1064 HOH HOH A . I 8 HOH 1064 2116 1065 HOH HOH A . I 8 HOH 1065 2117 1066 HOH HOH A . I 8 HOH 1066 2118 1067 HOH HOH A . I 8 HOH 1067 2119 1068 HOH HOH A . I 8 HOH 1068 2120 1069 HOH HOH A . I 8 HOH 1069 2121 1070 HOH HOH A . I 8 HOH 1070 2122 1071 HOH HOH A . I 8 HOH 1071 2123 1072 HOH HOH A . I 8 HOH 1072 2124 1073 HOH HOH A . I 8 HOH 1073 2125 1074 HOH HOH A . I 8 HOH 1074 2126 1075 HOH HOH A . I 8 HOH 1075 2127 1076 HOH HOH A . I 8 HOH 1076 2128 1077 HOH HOH A . I 8 HOH 1077 2129 1078 HOH HOH A . I 8 HOH 1078 2130 1079 HOH HOH A . I 8 HOH 1079 2131 1080 HOH HOH A . I 8 HOH 1080 2132 1081 HOH HOH A . I 8 HOH 1081 2133 1082 HOH HOH A . I 8 HOH 1082 2134 1083 HOH HOH A . I 8 HOH 1083 2135 1084 HOH HOH A . I 8 HOH 1084 2136 1085 HOH HOH A . I 8 HOH 1085 2137 1086 HOH HOH A . I 8 HOH 1086 2138 1087 HOH HOH A . I 8 HOH 1087 2139 1088 HOH HOH A . I 8 HOH 1088 2140 1089 HOH HOH A . I 8 HOH 1089 2141 1090 HOH HOH A . I 8 HOH 1090 2142 1091 HOH HOH A . I 8 HOH 1091 2143 1092 HOH HOH A . I 8 HOH 1092 2144 1093 HOH HOH A . I 8 HOH 1093 2145 1094 HOH HOH A . I 8 HOH 1094 2146 1095 HOH HOH A . I 8 HOH 1095 2147 1096 HOH HOH A . I 8 HOH 1096 2148 1097 HOH HOH A . I 8 HOH 1097 2149 1098 HOH HOH A . I 8 HOH 1098 2150 1099 HOH HOH A . I 8 HOH 1099 2151 1100 HOH HOH A . I 8 HOH 1100 2152 1101 HOH HOH A . I 8 HOH 1101 2153 1102 HOH HOH A . I 8 HOH 1102 2154 1103 HOH HOH A . I 8 HOH 1103 2155 1104 HOH HOH A . I 8 HOH 1104 2156 1105 HOH HOH A . I 8 HOH 1105 2157 1106 HOH HOH A . I 8 HOH 1106 2158 1107 HOH HOH A . I 8 HOH 1107 2159 1108 HOH HOH A . I 8 HOH 1108 2160 1109 HOH HOH A . I 8 HOH 1109 2161 1110 HOH HOH A . I 8 HOH 1110 2162 1111 HOH HOH A . I 8 HOH 1111 2163 1112 HOH HOH A . I 8 HOH 1112 2164 1113 HOH HOH A . I 8 HOH 1113 2165 1114 HOH HOH A . I 8 HOH 1114 2166 1115 HOH HOH A . I 8 HOH 1115 2167 1116 HOH HOH A . I 8 HOH 1116 2168 1117 HOH HOH A . I 8 HOH 1117 2169 1118 HOH HOH A . I 8 HOH 1118 2170 1119 HOH HOH A . I 8 HOH 1119 2171 1120 HOH HOH A . I 8 HOH 1120 2172 1121 HOH HOH A . I 8 HOH 1121 2173 1122 HOH HOH A . I 8 HOH 1122 2174 1123 HOH HOH A . I 8 HOH 1123 2175 1124 HOH HOH A . I 8 HOH 1124 2176 1125 HOH HOH A . I 8 HOH 1125 2177 1126 HOH HOH A . I 8 HOH 1126 2178 1127 HOH HOH A . I 8 HOH 1127 2179 1128 HOH HOH A . I 8 HOH 1128 2180 1129 HOH HOH A . I 8 HOH 1129 2181 1130 HOH HOH A . I 8 HOH 1130 2182 1131 HOH HOH A . I 8 HOH 1131 2183 1132 HOH HOH A . I 8 HOH 1132 2184 1133 HOH HOH A . I 8 HOH 1133 2185 1134 HOH HOH A . I 8 HOH 1134 2186 1135 HOH HOH A . I 8 HOH 1135 2187 1136 HOH HOH A . I 8 HOH 1136 2188 1137 HOH HOH A . I 8 HOH 1137 2189 1138 HOH HOH A . I 8 HOH 1138 2190 1139 HOH HOH A . I 8 HOH 1139 2191 1140 HOH HOH A . I 8 HOH 1140 2192 1141 HOH HOH A . I 8 HOH 1141 2193 1142 HOH HOH A . I 8 HOH 1142 2194 1143 HOH HOH A . I 8 HOH 1143 2195 1144 HOH HOH A . I 8 HOH 1144 2196 1145 HOH HOH A . I 8 HOH 1145 2197 1146 HOH HOH A . I 8 HOH 1146 2198 1147 HOH HOH A . I 8 HOH 1147 2199 1148 HOH HOH A . I 8 HOH 1148 2200 1149 HOH HOH A . I 8 HOH 1149 2201 1150 HOH HOH A . I 8 HOH 1150 2202 1151 HOH HOH A . I 8 HOH 1151 2203 1152 HOH HOH A . I 8 HOH 1152 2204 1153 HOH HOH A . I 8 HOH 1153 2205 1154 HOH HOH A . I 8 HOH 1154 2206 1155 HOH HOH A . I 8 HOH 1155 2207 1156 HOH HOH A . I 8 HOH 1156 2208 1157 HOH HOH A . I 8 HOH 1157 2209 1158 HOH HOH A . I 8 HOH 1158 2210 1159 HOH HOH A . I 8 HOH 1159 2211 1160 HOH HOH A . I 8 HOH 1160 2212 1161 HOH HOH A . I 8 HOH 1161 2213 1162 HOH HOH A . I 8 HOH 1162 2214 1163 HOH HOH A . I 8 HOH 1163 2215 1164 HOH HOH A . I 8 HOH 1164 2216 1165 HOH HOH A . I 8 HOH 1165 2217 1166 HOH HOH A . I 8 HOH 1166 2218 1167 HOH HOH A . I 8 HOH 1167 2219 1168 HOH HOH A . I 8 HOH 1168 2220 1169 HOH HOH A . I 8 HOH 1169 2221 1170 HOH HOH A . I 8 HOH 1170 2222 1171 HOH HOH A . I 8 HOH 1171 2223 1172 HOH HOH A . I 8 HOH 1172 2224 1173 HOH HOH A . I 8 HOH 1173 2225 1174 HOH HOH A . I 8 HOH 1174 2226 1175 HOH HOH A . I 8 HOH 1175 2227 1176 HOH HOH A . I 8 HOH 1176 2228 1177 HOH HOH A . I 8 HOH 1177 2229 1178 HOH HOH A . I 8 HOH 1178 2230 1179 HOH HOH A . I 8 HOH 1179 2231 1180 HOH HOH A . I 8 HOH 1180 2232 1181 HOH HOH A . I 8 HOH 1181 2233 1182 HOH HOH A . I 8 HOH 1182 2234 1183 HOH HOH A . I 8 HOH 1183 2235 1184 HOH HOH A . I 8 HOH 1184 2236 1185 HOH HOH A . I 8 HOH 1185 2237 1186 HOH HOH A . I 8 HOH 1186 2238 1187 HOH HOH A . I 8 HOH 1187 2239 1188 HOH HOH A . I 8 HOH 1188 2240 1189 HOH HOH A . I 8 HOH 1189 2241 1190 HOH HOH A . I 8 HOH 1190 2242 1191 HOH HOH A . I 8 HOH 1191 2243 1192 HOH HOH A . I 8 HOH 1192 2244 1193 HOH HOH A . I 8 HOH 1193 2245 1194 HOH HOH A . I 8 HOH 1194 2246 1195 HOH HOH A . I 8 HOH 1195 2247 1196 HOH HOH A . I 8 HOH 1196 2248 1197 HOH HOH A . I 8 HOH 1197 2249 1198 HOH HOH A . I 8 HOH 1198 2250 1199 HOH HOH A . I 8 HOH 1199 2251 1200 HOH HOH A . I 8 HOH 1200 2252 1201 HOH HOH A . I 8 HOH 1201 2253 1202 HOH HOH A . I 8 HOH 1202 2254 1203 HOH HOH A . I 8 HOH 1203 2255 1204 HOH HOH A . I 8 HOH 1204 2256 1205 HOH HOH A . I 8 HOH 1205 2257 1206 HOH HOH A . I 8 HOH 1206 2258 1207 HOH HOH A . I 8 HOH 1207 2259 1208 HOH HOH A . I 8 HOH 1208 2260 1209 HOH HOH A . I 8 HOH 1209 2261 1210 HOH HOH A . I 8 HOH 1210 2262 1211 HOH HOH A . I 8 HOH 1211 2263 1212 HOH HOH A . I 8 HOH 1212 2264 1213 HOH HOH A . I 8 HOH 1213 2265 1214 HOH HOH A . I 8 HOH 1214 2266 1215 HOH HOH A . I 8 HOH 1215 2267 1216 HOH HOH A . I 8 HOH 1216 2268 1217 HOH HOH A . I 8 HOH 1217 2269 1218 HOH HOH A . I 8 HOH 1218 2270 1219 HOH HOH A . I 8 HOH 1219 2271 1220 HOH HOH A . I 8 HOH 1220 2272 1221 HOH HOH A . I 8 HOH 1221 2273 1222 HOH HOH A . I 8 HOH 1222 2274 1223 HOH HOH A . I 8 HOH 1223 2275 1224 HOH HOH A . I 8 HOH 1224 2276 1225 HOH HOH A . I 8 HOH 1225 2277 1226 HOH HOH A . I 8 HOH 1226 2278 1227 HOH HOH A . I 8 HOH 1227 2279 1228 HOH HOH A . I 8 HOH 1228 2280 1229 HOH HOH A . I 8 HOH 1229 2281 1230 HOH HOH A . I 8 HOH 1230 2282 1231 HOH HOH A . I 8 HOH 1231 2283 1232 HOH HOH A . I 8 HOH 1232 2284 1233 HOH HOH A . I 8 HOH 1233 2285 1234 HOH HOH A . I 8 HOH 1234 2286 1235 HOH HOH A . I 8 HOH 1235 2287 1236 HOH HOH A . I 8 HOH 1236 2288 1237 HOH HOH A . I 8 HOH 1237 2289 1238 HOH HOH A . I 8 HOH 1238 2290 1239 HOH HOH A . I 8 HOH 1239 2291 1240 HOH HOH A . I 8 HOH 1240 2292 1241 HOH HOH A . I 8 HOH 1241 2293 1242 HOH HOH A . I 8 HOH 1242 2294 1243 HOH HOH A . I 8 HOH 1243 2295 1244 HOH HOH A . I 8 HOH 1244 2296 1245 HOH HOH A . I 8 HOH 1245 2297 1246 HOH HOH A . I 8 HOH 1246 2298 1247 HOH HOH A . I 8 HOH 1247 2299 1248 HOH HOH A . I 8 HOH 1248 2300 1249 HOH HOH A . I 8 HOH 1249 2301 1250 HOH HOH A . I 8 HOH 1250 2302 1251 HOH HOH A . I 8 HOH 1251 2303 1252 HOH HOH A . I 8 HOH 1252 2304 1253 HOH HOH A . I 8 HOH 1253 2305 1254 HOH HOH A . I 8 HOH 1254 2306 1255 HOH HOH A . I 8 HOH 1255 2307 1256 HOH HOH A . I 8 HOH 1256 2308 1257 HOH HOH A . I 8 HOH 1257 2309 1258 HOH HOH A . I 8 HOH 1258 2310 1259 HOH HOH A . I 8 HOH 1259 2311 1260 HOH HOH A . I 8 HOH 1260 2312 1261 HOH HOH A . I 8 HOH 1261 2313 1262 HOH HOH A . I 8 HOH 1262 2314 1263 HOH HOH A . I 8 HOH 1263 2315 1264 HOH HOH A . I 8 HOH 1264 2316 1265 HOH HOH A . I 8 HOH 1265 2317 1266 HOH HOH A . I 8 HOH 1266 2318 1267 HOH HOH A . I 8 HOH 1267 2319 1268 HOH HOH A . I 8 HOH 1268 2320 1269 HOH HOH A . I 8 HOH 1269 2321 1270 HOH HOH A . I 8 HOH 1270 2322 1271 HOH HOH A . I 8 HOH 1271 2323 1272 HOH HOH A . I 8 HOH 1272 2324 1273 HOH HOH A . I 8 HOH 1273 2325 1274 HOH HOH A . I 8 HOH 1274 2326 1275 HOH HOH A . I 8 HOH 1275 2327 1276 HOH HOH A . I 8 HOH 1276 2328 1277 HOH HOH A . I 8 HOH 1277 2329 1278 HOH HOH A . I 8 HOH 1278 2330 1279 HOH HOH A . I 8 HOH 1279 2331 1280 HOH HOH A . I 8 HOH 1280 2332 1281 HOH HOH A . I 8 HOH 1281 2333 1282 HOH HOH A . I 8 HOH 1282 2334 1283 HOH HOH A . I 8 HOH 1283 2335 1284 HOH HOH A . I 8 HOH 1284 2336 1285 HOH HOH A . I 8 HOH 1285 2337 1286 HOH HOH A . I 8 HOH 1286 2338 1287 HOH HOH A . I 8 HOH 1287 2339 1288 HOH HOH A . I 8 HOH 1288 2340 1289 HOH HOH A . I 8 HOH 1289 2341 1290 HOH HOH A . I 8 HOH 1290 2342 1291 HOH HOH A . I 8 HOH 1291 2343 1292 HOH HOH A . I 8 HOH 1292 2344 1293 HOH HOH A . I 8 HOH 1293 2345 1294 HOH HOH A . I 8 HOH 1294 2346 1295 HOH HOH A . I 8 HOH 1295 2347 1296 HOH HOH A . I 8 HOH 1296 2348 1297 HOH HOH A . I 8 HOH 1297 2349 1298 HOH HOH A . I 8 HOH 1298 2350 1299 HOH HOH A . I 8 HOH 1299 2351 1300 HOH HOH A . I 8 HOH 1300 2352 1301 HOH HOH A . I 8 HOH 1301 2353 1302 HOH HOH A . I 8 HOH 1302 2354 1303 HOH HOH A . I 8 HOH 1303 2355 1304 HOH HOH A . I 8 HOH 1304 2356 1305 HOH HOH A . I 8 HOH 1305 2357 1306 HOH HOH A . I 8 HOH 1306 2358 1307 HOH HOH A . I 8 HOH 1307 2359 1308 HOH HOH A . I 8 HOH 1308 2360 1309 HOH HOH A . I 8 HOH 1309 2361 1310 HOH HOH A . I 8 HOH 1310 2362 1311 HOH HOH A . I 8 HOH 1311 2363 1312 HOH HOH A . I 8 HOH 1312 2364 1313 HOH HOH A . I 8 HOH 1313 2365 1314 HOH HOH A . I 8 HOH 1314 2366 1315 HOH HOH A . I 8 HOH 1315 2367 1316 HOH HOH A . I 8 HOH 1316 2368 1317 HOH HOH A . I 8 HOH 1317 2369 1318 HOH HOH A . I 8 HOH 1318 2370 1319 HOH HOH A . I 8 HOH 1319 2371 1320 HOH HOH A . I 8 HOH 1320 2372 1321 HOH HOH A . I 8 HOH 1321 2373 1322 HOH HOH A . I 8 HOH 1322 2374 1323 HOH HOH A . I 8 HOH 1323 2375 1324 HOH HOH A . I 8 HOH 1324 2376 1325 HOH HOH A . I 8 HOH 1325 2377 1326 HOH HOH A . I 8 HOH 1326 2378 1327 HOH HOH A . I 8 HOH 1327 2379 1328 HOH HOH A . I 8 HOH 1328 2380 1329 HOH HOH A . I 8 HOH 1329 2381 1330 HOH HOH A . I 8 HOH 1330 2382 1331 HOH HOH A . I 8 HOH 1331 2383 1332 HOH HOH A . I 8 HOH 1332 2384 1333 HOH HOH A . I 8 HOH 1333 2385 1334 HOH HOH A . I 8 HOH 1334 2386 1335 HOH HOH A . I 8 HOH 1335 2387 1336 HOH HOH A . I 8 HOH 1336 2388 1337 HOH HOH A . I 8 HOH 1337 2389 1338 HOH HOH A . I 8 HOH 1338 2390 1339 HOH HOH A . I 8 HOH 1339 2391 1340 HOH HOH A . I 8 HOH 1340 2392 1341 HOH HOH A . I 8 HOH 1341 2393 1342 HOH HOH A . I 8 HOH 1342 2394 1343 HOH HOH A . I 8 HOH 1343 2395 1344 HOH HOH A . I 8 HOH 1344 2396 1345 HOH HOH A . I 8 HOH 1345 2397 1346 HOH HOH A . I 8 HOH 1346 2398 1347 HOH HOH A . I 8 HOH 1347 2399 1348 HOH HOH A . I 8 HOH 1348 2400 1349 HOH HOH A . I 8 HOH 1349 2401 1350 HOH HOH A . I 8 HOH 1350 2402 1351 HOH HOH A . I 8 HOH 1351 2403 1352 HOH HOH A . I 8 HOH 1352 2404 1353 HOH HOH A . I 8 HOH 1353 2405 1354 HOH HOH A . I 8 HOH 1354 2406 1355 HOH HOH A . I 8 HOH 1355 2407 1356 HOH HOH A . I 8 HOH 1356 2408 1357 HOH HOH A . I 8 HOH 1357 2409 1358 HOH HOH A . I 8 HOH 1358 2410 1359 HOH HOH A . I 8 HOH 1359 2411 1360 HOH HOH A . I 8 HOH 1360 2412 1361 HOH HOH A . I 8 HOH 1361 2413 1362 HOH HOH A . I 8 HOH 1362 2414 1363 HOH HOH A . I 8 HOH 1363 2415 1364 HOH HOH A . I 8 HOH 1364 2416 1365 HOH HOH A . I 8 HOH 1365 2417 1366 HOH HOH A . I 8 HOH 1366 2418 1367 HOH HOH A . I 8 HOH 1367 2419 1368 HOH HOH A . I 8 HOH 1368 2420 1369 HOH HOH A . I 8 HOH 1369 2421 1370 HOH HOH A . I 8 HOH 1370 2422 1371 HOH HOH A . I 8 HOH 1371 2423 1372 HOH HOH A . I 8 HOH 1372 2424 1373 HOH HOH A . I 8 HOH 1373 2425 1374 HOH HOH A . I 8 HOH 1374 2426 1375 HOH HOH A . I 8 HOH 1375 2427 1376 HOH HOH A . I 8 HOH 1376 2428 1377 HOH HOH A . I 8 HOH 1377 2429 1378 HOH HOH A . I 8 HOH 1378 2430 1379 HOH HOH A . I 8 HOH 1379 2431 1380 HOH HOH A . I 8 HOH 1380 2432 1381 HOH HOH A . I 8 HOH 1381 2433 1382 HOH HOH A . I 8 HOH 1382 2434 1383 HOH HOH A . I 8 HOH 1383 2435 1384 HOH HOH A . I 8 HOH 1384 2436 1385 HOH HOH A . I 8 HOH 1385 2437 1386 HOH HOH A . I 8 HOH 1386 2438 1387 HOH HOH A . I 8 HOH 1387 2439 1388 HOH HOH A . I 8 HOH 1388 2440 1389 HOH HOH A . I 8 HOH 1389 2441 1390 HOH HOH A . I 8 HOH 1390 2442 1391 HOH HOH A . I 8 HOH 1391 2443 1392 HOH HOH A . I 8 HOH 1392 2444 1393 HOH HOH A . I 8 HOH 1393 2445 1394 HOH HOH A . I 8 HOH 1394 2446 1395 HOH HOH A . I 8 HOH 1395 2447 1396 HOH HOH A . I 8 HOH 1396 2448 1397 HOH HOH A . I 8 HOH 1397 2449 1398 HOH HOH A . I 8 HOH 1398 2450 1399 HOH HOH A . I 8 HOH 1399 2451 1400 HOH HOH A . I 8 HOH 1400 2452 1401 HOH HOH A . I 8 HOH 1401 2453 1402 HOH HOH A . I 8 HOH 1402 2454 1403 HOH HOH A . I 8 HOH 1403 2455 1404 HOH HOH A . I 8 HOH 1404 2456 1405 HOH HOH A . I 8 HOH 1405 2457 1406 HOH HOH A . I 8 HOH 1406 2458 1407 HOH HOH A . I 8 HOH 1407 2459 1408 HOH HOH A . I 8 HOH 1408 2460 1409 HOH HOH A . I 8 HOH 1409 2461 1410 HOH HOH A . I 8 HOH 1410 2462 1411 HOH HOH A . I 8 HOH 1411 2463 1412 HOH HOH A . I 8 HOH 1412 2464 1413 HOH HOH A . I 8 HOH 1413 2465 1414 HOH HOH A . I 8 HOH 1414 2466 1415 HOH HOH A . I 8 HOH 1415 2467 1416 HOH HOH A . I 8 HOH 1416 2468 1417 HOH HOH A . I 8 HOH 1417 2469 1418 HOH HOH A . I 8 HOH 1418 2470 1419 HOH HOH A . I 8 HOH 1419 2471 1420 HOH HOH A . I 8 HOH 1420 2472 1421 HOH HOH A . I 8 HOH 1421 2473 1422 HOH HOH A . I 8 HOH 1422 2474 1423 HOH HOH A . I 8 HOH 1423 2475 1424 HOH HOH A . I 8 HOH 1424 2476 1425 HOH HOH A . I 8 HOH 1425 2477 1426 HOH HOH A . I 8 HOH 1426 2478 1427 HOH HOH A . I 8 HOH 1427 2479 1428 HOH HOH A . I 8 HOH 1428 2480 1429 HOH HOH A . I 8 HOH 1429 2481 1430 HOH HOH A . I 8 HOH 1430 2482 1431 HOH HOH A . I 8 HOH 1431 2483 1432 HOH HOH A . I 8 HOH 1432 2484 1433 HOH HOH A . I 8 HOH 1433 2485 1434 HOH HOH A . I 8 HOH 1434 2486 1435 HOH HOH A . I 8 HOH 1435 2487 1436 HOH HOH A . I 8 HOH 1436 2488 1437 HOH HOH A . I 8 HOH 1437 2489 1438 HOH HOH A . I 8 HOH 1438 2490 1439 HOH HOH A . I 8 HOH 1439 2491 1440 HOH HOH A . I 8 HOH 1440 2492 1441 HOH HOH A . I 8 HOH 1441 2493 1442 HOH HOH A . I 8 HOH 1442 2494 1443 HOH HOH A . I 8 HOH 1443 2495 1444 HOH HOH A . I 8 HOH 1444 2496 1445 HOH HOH A . I 8 HOH 1445 2497 1446 HOH HOH A . I 8 HOH 1446 2498 1447 HOH HOH A . I 8 HOH 1447 2499 1448 HOH HOH A . I 8 HOH 1448 2500 1449 HOH HOH A . I 8 HOH 1449 2501 1450 HOH HOH A . I 8 HOH 1450 2502 1451 HOH HOH A . I 8 HOH 1451 2503 1452 HOH HOH A . I 8 HOH 1452 2504 1453 HOH HOH A . I 8 HOH 1453 2505 1454 HOH HOH A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 96.2 ? 2 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 106.5 ? 3 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 98.5 ? 4 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 O32 ? F WZ1 . ? A WZ1 1050 ? 1_555 152.6 ? 5 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 O32 ? F WZ1 . ? A WZ1 1050 ? 1_555 92.8 ? 6 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 O32 ? F WZ1 . ? A WZ1 1050 ? 1_555 97.5 ? 7 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 O22 ? F WZ1 . ? A WZ1 1050 ? 1_555 85.2 ? 8 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 O22 ? F WZ1 . ? A WZ1 1050 ? 1_555 144.8 ? 9 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 O22 ? F WZ1 . ? A WZ1 1050 ? 1_555 114.9 ? 10 O32 ? F WZ1 . ? A WZ1 1050 ? 1_555 ZN ? D ZN . ? A ZN 1048 ? 1_555 O22 ? F WZ1 . ? A WZ1 1050 ? 1_555 72.8 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2008-07-01 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-10-25 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' 3 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _phasing.method MR # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal DENZO . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data reduction' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 1 SCALEPACK . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data scaling' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 2 CNS . ? package 'Axel T. Brunger' axel.brunger@yale.edu refinement http://cns.csb.yale.edu/v1.1/ Fortran_77 ? 3 REFMAC . ? program 'Murshudov, G.N.' ccp4@dl.ac.uk refinement http://www.ccp4.ac.uk/main.html Fortran_77 ? 4 PDB_EXTRACT 3.004 'September 10, 2007' package PDB sw-help@rcsb.rutgers.edu 'data extraction' http://pdb.rutgers.edu/software/ C++ ? 5 ADSC Quantum ? ? ? ? 'data collection' ? ? ? 6 CNS . ? ? ? ? phasing ? ? ? 7 # _pdbx_database_remark.id 999 _pdbx_database_remark.text ;SEQUENCE E970K conflict in UNP entry Q24451 ; # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 56 ? ? -105.11 78.32 2 1 HIS A 79 ? ? -151.78 84.74 3 1 TRP A 95 ? ? -170.91 -83.65 4 1 ASP A 106 ? ? -132.50 -61.01 5 1 THR A 162 ? ? 69.11 -67.59 6 1 GLN A 227 ? ? -139.31 -44.21 7 1 ASP A 340 ? ? -172.88 -171.73 8 1 LYS A 345 ? ? -87.14 -70.24 9 1 SER A 411 ? ? 41.96 -126.36 10 1 SER A 411 ? ? 48.95 -130.46 11 1 ILE A 549 ? ? -140.73 -48.67 12 1 LEU A 550 ? ? -171.16 117.58 13 1 PRO A 562 ? ? -84.69 40.41 14 1 ARG A 653 ? ? -173.30 147.78 15 1 ASN A 732 ? ? -92.20 57.35 16 1 GLN A 742 ? A -119.60 76.69 17 1 SER A 762 ? ? 72.44 -4.05 18 1 ILE A 831 ? ? -118.03 75.83 19 1 SER A 833 ? ? -152.15 -15.09 20 1 ASP A 839 ? ? -124.04 -160.35 21 1 GLU A 991 ? ? 22.70 82.27 22 1 GLU A 992 ? ? -116.91 -161.77 23 1 HIS A 993 ? ? 36.17 93.75 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'PHOSPHATE ION' PO4 4 'ZINC ION' ZN 5 '(4R)-2-METHYLPENTANE-2,4-DIOL' MRD 6 'methyl 3-S-alpha-D-mannopyranosyl-3-thio-alpha-D-mannopyranoside' WZ1 7 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 8 water HOH #