data_3BUB # _entry.id 3BUB # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3BUB RCSB RCSB045964 WWPDB D_1000045964 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1HTY 'dGMII + Tris' unspecified PDB 1HWW 'dGMII + Swainsonine' unspecified PDB 1HXK 'dGMII + Deoxymannojirimicin' unspecified PDB 1PS2 'dGMII + Kifunensine' unspecified PDB 1QWN 'dGMII + 5fluoro-Gulosylfluoride' unspecified PDB 1QX1 'dGMII_D341N + 2F-mannosylF' unspecified PDB 1R33 'dGMII + 5-thio-D-mannopyranosylamine' unspecified PDB 1R34 'dGMII + 5-thio-D-mannopyranosylamidinium salt' unspecified PDB 1TQS 'dGMII + Salacinol' unspecified PDB 1TQT 'dGMII + Diastereomer of Salacinol' unspecified PDB 1TQU 'dGMII + Ghavamiol' unspecified PDB 1TQV 'dGMII + Blintol' unspecified PDB 1TQW 'dGMII + Blintol Diastereomer' unspecified PDB 2ALW 'dGMII + Noeuromycin' unspecified PDB 2F18 'dGMII + (2R,3R,4S)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' unspecified PDB 2F1A 'dGMII + (2R,3R,4S)-2-({[(1S)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' unspecified PDB 2F1B 'dGMII + (2R,3R,4S,5R)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)-5-methylpyrrolidine-3,4-diol' unspecified PDB 2F7O 'dGMII + Mannostatin A' unspecified PDB 2F7P 'dGMII + Benzyl-mannostatin A' unspecified PDB 2F7Q 'dGMII + Aminocyclopentitetrol' unspecified PDB 2F7R 'dGMII + Benzyl-aminocyclopentitetrol' unspecified PDB 3BUD 'dGMII_D204A + MPD, NAG, Zn, PO4' unspecified PDB 3BUI 'dGMII_D204A + MPD, TRIS, Zn' unspecified # _pdbx_database_status.entry_id 3BUB _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2008-01-02 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Kuntz, D.A.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title ;Probing the substrate specificity of Golgi alpha-mannosidase II by use of synthetic oligosaccharides and a catalytic nucleophile mutant. ; _citation.journal_abbrev J.Am.Chem.Soc. _citation.journal_volume 130 _citation.page_first 8975 _citation.page_last 8983 _citation.year 2008 _citation.journal_id_ASTM JACSAT _citation.country US _citation.journal_id_ISSN 0002-7863 _citation.journal_id_CSD 0004 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 18558690 _citation.pdbx_database_id_DOI 10.1021/ja711248y # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Zhong, W.' 1 primary 'Kuntz, D.A.' 2 primary 'Ember, B.' 3 primary 'Singh, H.' 4 primary 'Moremen, K.W.' 5 primary 'Rose, D.R.' 6 primary 'Boons, G.J.' 7 # _cell.length_a 68.765 _cell.length_b 109.624 _cell.length_c 138.649 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3BUB _cell.pdbx_unique_axis ? _cell.Z_PDB 4 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.entry_id 3BUB _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.Int_Tables_number 19 _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Alpha-mannosidase 2' 119701.617 1 3.2.1.114 ? 'Catalytic domain; UNP residues 76-1108' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 4 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 3 ? ? ? ? 5 water nat water 18.015 1470 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Alpha-mannosidase II, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ASP n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASP n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'Fruit fly' _entity_src_gen.gene_src_genus ? _entity_src_gen.pdbx_gene_src_gene 'alpha-Man-II, GmII' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id ? _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id ? _entity_src_gen.host_org_genus ? _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMTBIP_NHIS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MAN2_DROME _struct_ref.pdbx_db_accession Q24451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHND PGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEAN SHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWD NKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN VLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSD NYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE ALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFY VSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLL RKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPN GPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQ FIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIY RLVLEKVNNCVRPSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKT QRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS ; _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3BUB _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q24451 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3BUB ARG A 1 ? UNP Q24451 ? ? 'EXPRESSION TAG' 1 1 1 3BUB SER A 2 ? UNP Q24451 ? ? 'EXPRESSION TAG' 2 2 1 3BUB SER A 3 ? UNP Q24451 ? ? 'EXPRESSION TAG' 3 3 1 3BUB HIS A 4 ? UNP Q24451 ? ? 'EXPRESSION TAG' 4 4 1 3BUB HIS A 5 ? UNP Q24451 ? ? 'EXPRESSION TAG' 5 5 1 3BUB HIS A 6 ? UNP Q24451 ? ? 'EXPRESSION TAG' 6 6 1 3BUB HIS A 7 ? UNP Q24451 ? ? 'EXPRESSION TAG' 7 7 1 3BUB HIS A 8 ? UNP Q24451 ? ? 'EXPRESSION TAG' 8 8 1 3BUB HIS A 9 ? UNP Q24451 ? ? 'EXPRESSION TAG' 9 9 1 3BUB GLY A 10 ? UNP Q24451 ? ? 'EXPRESSION TAG' 10 10 1 3BUB GLU A 11 ? UNP Q24451 ? ? 'EXPRESSION TAG' 11 11 1 3BUB PHE A 12 ? UNP Q24451 ? ? 'EXPRESSION TAG' 12 12 1 3BUB LYS A 907 ? UNP Q24451 GLU 970 'SEE REMARK 999' 907 13 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.crystals_number 1 _exptl.entry_id 3BUB _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 2.18 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 43.65 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details ;Tris, NaCl, PEG6000, MPD; Tris found in the active site under normal crystallization conditions was removed by soaking crystals in phosphate buffered resevoir solution, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K ; _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2007-04-20 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9770 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.pdbx_wavelength_list 0.9770 _diffrn_source.pdbx_wavelength ? _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE A1' _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline A1 # _reflns.entry_id 3BUB _reflns.observed_criterion_sigma_F 0 _reflns.observed_criterion_sigma_I 0 _reflns.d_resolution_high 1.38 _reflns.d_resolution_low 20 _reflns.number_all 214738 _reflns.number_obs 211715 _reflns.percent_possible_obs 98.5 _reflns.pdbx_Rmerge_I_obs 0.06 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 20.7 _reflns.B_iso_Wilson_estimate 18.0 _reflns.pdbx_redundancy 6.4 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.38 _reflns_shell.d_res_low 1.40 _reflns_shell.percent_possible_obs ? _reflns_shell.percent_possible_all 82.0 _reflns_shell.Rmerge_I_obs 0.33 _reflns_shell.meanI_over_sigI_obs 3.5 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_redundancy 2.3 _reflns_shell.number_unique_all 3723 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 3BUB _refine.ls_d_res_high 1.380 _refine.ls_d_res_low 19.810 _refine.pdbx_ls_sigma_F 0.00 _refine.ls_percent_reflns_obs 97.990 _refine.ls_number_reflns_obs 210432 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.ls_R_factor_obs 0.180 _refine.ls_R_factor_R_work 0.180 _refine.ls_R_factor_R_free 0.204 _refine.ls_percent_reflns_R_free 1.500 _refine.ls_number_reflns_R_free 3138 _refine.B_iso_mean 14.616 _refine.aniso_B[1][1] 0.010 _refine.aniso_B[2][2] -0.010 _refine.aniso_B[3][3] 0.000 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.correlation_coeff_Fo_to_Fc 0.961 _refine.correlation_coeff_Fo_to_Fc_free 0.946 _refine.pdbx_overall_ESU_R 0.062 _refine.pdbx_overall_ESU_R_Free 0.063 _refine.overall_SU_ML 0.042 _refine.overall_SU_B 1.042 _refine.solvent_model_details MASK _refine.pdbx_solvent_vdw_probe_radii 1.200 _refine.pdbx_solvent_ion_probe_radii 0.800 _refine.pdbx_solvent_shrinkage_radii 0.800 _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_ls_sigma_I ? _refine.ls_number_reflns_all 214738 _refine.ls_R_factor_all ? _refine.ls_redundancy_reflns_obs ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_starting_model 'PDB entry 1HTY' _refine.pdbx_stereochem_target_val_spec_case ? _refine.solvent_model_param_bsol ? _refine.solvent_model_param_ksol ? _refine.occupancy_max ? _refine.occupancy_min ? _refine.pdbx_isotropic_thermal_model ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 3BUB _refine_analyze.Luzzati_coordinate_error_obs 0.16 _refine_analyze.Luzzati_sigma_a_obs 0.14 _refine_analyze.Luzzati_d_res_low_obs ? _refine_analyze.Luzzati_coordinate_error_free ? _refine_analyze.Luzzati_sigma_a_free ? _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8196 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 39 _refine_hist.number_atoms_solvent 1470 _refine_hist.number_atoms_total 9705 _refine_hist.d_res_high 1.380 _refine_hist.d_res_low 19.810 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 8882 0.014 0.021 ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 12138 1.544 1.937 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 1115 6.080 5.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 439 36.699 23.667 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 1515 12.552 15.000 ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 61 18.041 15.000 ? 'X-RAY DIFFRACTION' ? r_chiral_restr 1285 0.103 0.200 ? 'X-RAY DIFFRACTION' ? r_gen_planes_refined 6949 0.008 0.020 ? 'X-RAY DIFFRACTION' ? r_nbd_refined 4462 0.206 0.200 ? 'X-RAY DIFFRACTION' ? r_nbtor_refined 6151 0.316 0.200 ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 1330 0.152 0.200 ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined 2 0.038 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 85 0.227 0.200 ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 82 0.156 0.200 ? 'X-RAY DIFFRACTION' ? r_mcbond_it 5430 1.044 1.500 ? 'X-RAY DIFFRACTION' ? r_mcangle_it 8681 1.680 2.000 ? 'X-RAY DIFFRACTION' ? r_scbond_it 3895 2.411 3.000 ? 'X-RAY DIFFRACTION' ? r_scangle_it 3432 3.720 4.500 ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.d_res_high 1.380 _refine_ls_shell.d_res_low 1.416 _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.percent_reflns_obs 83.890 _refine_ls_shell.number_reflns_R_work 12978 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.277 _refine_ls_shell.R_factor_R_free 0.274 _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 196 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.number_reflns_all 13174 _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 3BUB _struct.title 'Golgi alpha-mannosidase II with an empty active site' _struct.pdbx_descriptor 'Alpha-mannosidase 2 (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3BUB _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'GLYCOSYL HYDROLASE FAMILY 38, Glycosidase, Golgi apparatus, Membrane, Signal-anchor, Transmembrane, HYDROLASE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 4 ? F N N 4 ? G N N 5 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? HIS A 139 ? GLU A 130 HIS A 139 1 ? 10 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? MET A 290 ? GLN A 284 MET A 290 5 ? 7 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.060 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.017 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.085 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.040 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 2.011 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 1046 1_555 ? ? ? ? ? ? ? 1.457 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 -8.08 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 6.52 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 2 ? E ? 6 ? F ? 5 ? G ? 5 ? H ? 12 ? I ? 5 ? J ? 8 ? K ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel H 6 7 ? anti-parallel H 7 8 ? anti-parallel H 8 9 ? anti-parallel H 9 10 ? anti-parallel H 10 11 ? anti-parallel H 11 12 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel J 6 7 ? anti-parallel J 7 8 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASP A 341 ? VAL A 333 ASP A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 ALA A 408 ? ARG A 410 ? ALA A 408 ARG A 410 D 2 ASN A 413 ? TYR A 414 ? ASN A 413 TYR A 414 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 E 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 F 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 F 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 F 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 F 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 F 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 G 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 G 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 G 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 G 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 G 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 H 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 H 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 H 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 H 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 H 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 H 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 H 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 H 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 H 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 H 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 H 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 H 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 I 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 J 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 J 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 J 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 J 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 J 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 J 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 J 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 J 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 K 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 K 2 THR A 972 ? ARG A 981 ? THR A 972 ARG A 981 K 3 THR A 1036 ? SER A 1044 ? THR A 1036 SER A 1044 K 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 K 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O SER A 401 ? O SER A 401 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O LEU A 225 ? O LEU A 225 N ALA A 202 ? N ALA A 202 B 1 2 O LEU A 334 ? O LEU A 334 N LYS A 82 ? N LYS A 82 B 2 3 N VAL A 85 ? N VAL A 85 O GLN A 375 ? O GLN A 375 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N ARG A 410 ? N ARG A 410 O ASN A 413 ? O ASN A 413 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 E 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 F 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 F 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 F 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 F 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 G 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 G 2 3 N VAL A 573 ? N VAL A 573 O TYR A 616 ? O TYR A 616 G 3 4 O ARG A 617 ? O ARG A 617 N SER A 593 ? N SER A 593 G 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 H 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 H 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 H 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 H 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 H 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 H 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 H 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 H 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 H 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 H 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 H 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 J 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 J 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 J 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 J 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 J 5 6 N ILE A 790 ? N ILE A 790 O GLN A 866 ? O GLN A 866 J 6 7 O MET A 865 ? O MET A 865 N GLY A 853 ? N GLY A 853 J 7 8 O LEU A 852 ? O LEU A 852 N ILE A 831 ? N ILE A 831 K 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 K 2 3 N LEU A 979 ? N LEU A 979 O ALA A 1037 ? O ALA A 1037 K 3 4 O SER A 1042 ? O SER A 1042 N ALA A 1007 ? N ALA A 1007 K 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 1046' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE ZN A 1047' AC3 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE MPD A 1048' AC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MPD A 1049' AC5 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MPD A 1050' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 3 LYS A 154 ? LYS A 154 . ? 1_555 ? 2 AC1 3 ASN A 194 ? ASN A 194 . ? 1_555 ? 3 AC1 3 HOH G . ? HOH A 2328 . ? 1_555 ? 4 AC2 5 HIS A 90 ? HIS A 90 . ? 1_555 ? 5 AC2 5 ASP A 92 ? ASP A 92 . ? 1_555 ? 6 AC2 5 ASP A 204 ? ASP A 204 . ? 1_555 ? 7 AC2 5 HIS A 471 ? HIS A 471 . ? 1_555 ? 8 AC2 5 HOH G . ? HOH A 1051 . ? 1_555 ? 9 AC3 8 LYS A 63 ? LYS A 63 . ? 1_555 ? 10 AC3 8 GLN A 64 ? GLN A 64 . ? 1_555 ? 11 AC3 8 TYR A 267 ? TYR A 267 . ? 1_555 ? 12 AC3 8 HIS A 273 ? HIS A 273 . ? 1_555 ? 13 AC3 8 HOH G . ? HOH A 1071 . ? 1_555 ? 14 AC3 8 HOH G . ? HOH A 1072 . ? 1_555 ? 15 AC3 8 HOH G . ? HOH A 1519 . ? 1_555 ? 16 AC3 8 HOH G . ? HOH A 2188 . ? 1_555 ? 17 AC4 4 TYR A 435 ? TYR A 435 . ? 1_555 ? 18 AC4 4 GLN A 491 ? GLN A 491 . ? 1_555 ? 19 AC4 4 GLN A 498 ? GLN A 498 . ? 1_555 ? 20 AC4 4 HOH G . ? HOH A 1170 . ? 1_555 ? 21 AC5 4 ARG A 457 ? ARG A 457 . ? 4_465 ? 22 AC5 4 LYS A 495 ? LYS A 495 . ? 4_465 ? 23 AC5 4 HOH G . ? HOH A 1479 . ? 1_555 ? 24 AC5 4 HOH G . ? HOH A 2182 . ? 1_555 ? # _atom_sites.entry_id 3BUB _atom_sites.fract_transf_matrix[1][1] 0.014542 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009122 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007212 _atom_sites.fract_transf_vector[1] 0.000000 _atom_sites.fract_transf_vector[2] 0.000000 _atom_sites.fract_transf_vector[3] 0.000000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . GLN A 1 30 ? 46.782 34.124 -18.803 1.00 32.19 ? 30 GLN A N 1 ATOM 2 C CA . GLN A 1 30 ? 45.390 34.192 -19.339 1.00 31.75 ? 30 GLN A CA 1 ATOM 3 C C . GLN A 1 30 ? 44.538 35.210 -18.589 1.00 30.22 ? 30 GLN A C 1 ATOM 4 O O . GLN A 1 30 ? 44.225 35.050 -17.407 1.00 31.22 ? 30 GLN A O 1 ATOM 5 C CB . GLN A 1 30 ? 44.720 32.816 -19.368 1.00 32.61 ? 30 GLN A CB 1 ATOM 6 C CG . GLN A 1 30 ? 43.331 32.850 -20.001 1.00 35.80 ? 30 GLN A CG 1 ATOM 7 C CD . GLN A 1 30 ? 43.347 33.202 -21.482 1.00 39.34 ? 30 GLN A CD 1 ATOM 8 O OE1 . GLN A 1 30 ? 44.170 32.679 -22.240 1.00 40.67 ? 30 GLN A OE1 1 ATOM 9 N NE2 . GLN A 1 30 ? 42.443 34.100 -21.897 1.00 40.33 ? 30 GLN A NE2 1 ATOM 10 N N . CYS A 1 31 ? 44.288 36.242 -19.394 1.00 27.89 ? 31 CYS A N 1 ATOM 11 C CA . CYS A 1 31 ? 43.537 37.354 -18.832 1.00 25.06 ? 31 CYS A CA 1 ATOM 12 C C . CYS A 1 31 ? 42.047 37.039 -18.811 1.00 23.19 ? 31 CYS A C 1 ATOM 13 O O . CYS A 1 31 ? 41.532 36.430 -19.753 1.00 22.37 ? 31 CYS A O 1 ATOM 14 C CB . CYS A 1 31 ? 43.800 38.582 -19.690 1.00 24.92 ? 31 CYS A CB 1 ATOM 15 S SG . CYS A 1 31 ? 45.539 39.095 -19.613 1.00 26.54 ? 31 CYS A SG 1 ATOM 16 N N . GLN A 1 32 ? 41.358 37.458 -17.751 1.00 20.68 ? 32 GLN A N 1 ATOM 17 C CA . GLN A 1 32 ? 39.895 37.438 -17.720 1.00 19.64 ? 32 GLN A CA 1 ATOM 18 C C . GLN A 1 32 ? 39.352 38.363 -18.799 1.00 17.46 ? 32 GLN A C 1 ATOM 19 O O . GLN A 1 32 ? 39.890 39.446 -19.035 1.00 15.80 ? 32 GLN A O 1 ATOM 20 C CB . GLN A 1 32 ? 39.341 37.969 -16.393 1.00 21.07 ? 32 GLN A CB 1 ATOM 21 C CG . GLN A 1 32 ? 39.227 36.987 -15.262 1.00 23.87 ? 32 GLN A CG 1 ATOM 22 C CD . GLN A 1 32 ? 38.226 37.458 -14.196 1.00 25.92 ? 32 GLN A CD 1 ATOM 23 O OE1 . GLN A 1 32 ? 37.111 36.915 -14.106 1.00 25.85 ? 32 GLN A OE1 1 ATOM 24 N NE2 . GLN A 1 32 ? 38.616 38.463 -13.397 1.00 28.25 ? 32 GLN A NE2 1 ATOM 25 N N . ASP A 1 33 ? 38.281 37.934 -19.441 1.00 15.79 ? 33 ASP A N 1 ATOM 26 C CA . ASP A 1 33 ? 37.544 38.769 -20.388 1.00 15.04 ? 33 ASP A CA 1 ATOM 27 C C . ASP A 1 33 ? 36.630 39.748 -19.631 1.00 14.86 ? 33 ASP A C 1 ATOM 28 O O . ASP A 1 33 ? 35.703 39.339 -18.945 1.00 16.56 ? 33 ASP A O 1 ATOM 29 C CB . ASP A 1 33 ? 36.739 37.841 -21.309 1.00 15.09 ? 33 ASP A CB 1 ATOM 30 C CG . ASP A 1 33 ? 36.094 38.550 -22.471 1.00 18.10 ? 33 ASP A CG 1 ATOM 31 O OD1 . ASP A 1 33 ? 35.579 39.680 -22.337 1.00 18.69 ? 33 ASP A OD1 1 ATOM 32 O OD2 . ASP A 1 33 ? 35.998 37.991 -23.578 1.00 22.11 ? 33 ASP A OD2 1 ATOM 33 N N . VAL A 1 34 ? 36.863 41.047 -19.766 1.00 10.54 ? 34 VAL A N 1 ATOM 34 C CA . VAL A 1 34 ? 36.104 42.034 -19.007 1.00 10.25 ? 34 VAL A CA 1 ATOM 35 C C . VAL A 1 34 ? 34.895 42.578 -19.761 1.00 9.40 ? 34 VAL A C 1 ATOM 36 O O . VAL A 1 34 ? 34.226 43.503 -19.295 1.00 8.98 ? 34 VAL A O 1 ATOM 37 C CB . VAL A 1 34 ? 37.025 43.192 -18.558 1.00 10.20 ? 34 VAL A CB 1 ATOM 38 C CG1 . VAL A 1 34 ? 38.193 42.655 -17.736 1.00 12.08 ? 34 VAL A CG1 1 ATOM 39 C CG2 . VAL A 1 34 ? 37.557 43.989 -19.733 1.00 11.35 ? 34 VAL A CG2 1 ATOM 40 N N . VAL A 1 35 ? 34.625 42.024 -20.950 1.00 8.96 ? 35 VAL A N 1 ATOM 41 C CA . VAL A 1 35 ? 33.548 42.539 -21.797 1.00 9.41 ? 35 VAL A CA 1 ATOM 42 C C . VAL A 1 35 ? 32.362 41.587 -21.965 1.00 9.14 ? 35 VAL A C 1 ATOM 43 O O . VAL A 1 35 ? 31.223 42.001 -21.926 1.00 9.16 ? 35 VAL A O 1 ATOM 44 C CB . VAL A 1 35 ? 34.098 42.888 -23.192 1.00 9.48 ? 35 VAL A CB 1 ATOM 45 C CG1 . VAL A 1 35 ? 32.964 43.335 -24.141 1.00 10.30 ? 35 VAL A CG1 1 ATOM 46 C CG2 . VAL A 1 35 ? 35.200 43.956 -23.081 1.00 10.98 ? 35 VAL A CG2 1 ATOM 47 N N . GLN A 1 36 ? 32.680 40.312 -22.194 1.00 10.54 ? 36 GLN A N 1 ATOM 48 C CA . GLN A 1 36 ? 31.685 39.350 -22.739 1.00 12.57 ? 36 GLN A CA 1 ATOM 49 C C . GLN A 1 36 ? 30.963 38.474 -21.728 1.00 14.86 ? 36 GLN A C 1 ATOM 50 O O . GLN A 1 36 ? 29.938 37.855 -22.064 1.00 18.14 ? 36 GLN A O 1 ATOM 51 C CB . GLN A 1 36 ? 32.346 38.481 -23.790 1.00 12.26 ? 36 GLN A CB 1 ATOM 52 C CG . GLN A 1 36 ? 33.025 39.320 -24.812 1.00 13.05 ? 36 GLN A CG 1 ATOM 53 C CD . GLN A 1 36 ? 33.512 38.494 -25.960 1.00 13.82 ? 36 GLN A CD 1 ATOM 54 O OE1 . GLN A 1 36 ? 32.755 38.267 -26.907 1.00 15.35 ? 36 GLN A OE1 1 ATOM 55 N NE2 . GLN A 1 36 ? 34.748 38.024 -25.884 1.00 13.87 ? 36 GLN A NE2 1 ATOM 56 N N . ASP A 1 37 ? 31.479 38.395 -20.507 1.00 15.46 ? 37 ASP A N 1 ATOM 57 C CA . ASP A 1 37 ? 30.897 37.526 -19.488 1.00 16.68 ? 37 ASP A CA 1 ATOM 58 C C . ASP A 1 37 ? 30.241 38.412 -18.436 1.00 15.37 ? 37 ASP A C 1 ATOM 59 O O . ASP A 1 37 ? 30.939 39.148 -17.748 1.00 17.87 ? 37 ASP A O 1 ATOM 60 C CB . ASP A 1 37 ? 31.992 36.672 -18.834 1.00 18.00 ? 37 ASP A CB 1 ATOM 61 C CG . ASP A 1 37 ? 32.695 35.738 -19.805 1.00 21.14 ? 37 ASP A CG 1 ATOM 62 O OD1 . ASP A 1 37 ? 32.000 35.111 -20.635 1.00 25.01 ? 37 ASP A OD1 1 ATOM 63 O OD2 . ASP A 1 37 ? 33.940 35.554 -19.792 1.00 24.45 ? 37 ASP A OD2 1 ATOM 64 N N . VAL A 1 38 ? 28.921 38.356 -18.314 1.00 14.10 ? 38 VAL A N 1 ATOM 65 C CA . VAL A 1 38 ? 28.245 39.097 -17.227 1.00 13.39 ? 38 VAL A CA 1 ATOM 66 C C . VAL A 1 38 ? 28.401 38.388 -15.870 1.00 13.04 ? 38 VAL A C 1 ATOM 67 O O . VAL A 1 38 ? 27.936 37.255 -15.705 1.00 13.07 ? 38 VAL A O 1 ATOM 68 C CB . VAL A 1 38 ? 26.760 39.335 -17.549 1.00 13.26 ? 38 VAL A CB 1 ATOM 69 C CG1 . VAL A 1 38 ? 26.037 40.054 -16.419 1.00 14.53 ? 38 VAL A CG1 1 ATOM 70 C CG2 . VAL A 1 38 ? 26.611 40.077 -18.916 1.00 13.80 ? 38 VAL A CG2 1 ATOM 71 N N . PRO A 1 39 ? 29.072 39.015 -14.909 1.00 12.10 ? 39 PRO A N 1 ATOM 72 C CA . PRO A 1 39 ? 29.298 38.354 -13.615 1.00 11.73 ? 39 PRO A CA 1 ATOM 73 C C . PRO A 1 39 ? 28.009 38.005 -12.915 1.00 11.91 ? 39 PRO A C 1 ATOM 74 O O . PRO A 1 39 ? 27.024 38.729 -12.948 1.00 11.79 ? 39 PRO A O 1 ATOM 75 C CB . PRO A 1 39 ? 30.059 39.418 -12.818 1.00 12.28 ? 39 PRO A CB 1 ATOM 76 C CG . PRO A 1 39 ? 30.776 40.178 -13.896 1.00 11.00 ? 39 PRO A CG 1 ATOM 77 C CD . PRO A 1 39 ? 29.752 40.335 -14.983 1.00 12.27 ? 39 PRO A CD 1 ATOM 78 N N . ASN A 1 40 ? 28.013 36.829 -12.283 1.00 12.67 ? 40 ASN A N 1 ATOM 79 C CA . ASN A 1 40 ? 26.864 36.430 -11.518 1.00 13.65 ? 40 ASN A CA 1 ATOM 80 C C . ASN A 1 40 ? 27.142 36.803 -10.065 1.00 12.78 ? 40 ASN A C 1 ATOM 81 O O . ASN A 1 40 ? 28.051 36.252 -9.428 1.00 14.19 ? 40 ASN A O 1 ATOM 82 C CB . ASN A 1 40 ? 26.604 34.919 -11.706 1.00 15.42 ? 40 ASN A CB 1 ATOM 83 C CG . ASN A 1 40 ? 25.419 34.427 -10.902 1.00 19.32 ? 40 ASN A CG 1 ATOM 84 O OD1 . ASN A 1 40 ? 24.432 35.151 -10.697 1.00 25.43 ? 40 ASN A OD1 1 ATOM 85 N ND2 . ASN A 1 40 ? 25.504 33.183 -10.439 1.00 26.59 ? 40 ASN A ND2 1 ATOM 86 N N . VAL A 1 41 ? 26.397 37.787 -9.584 1.00 11.57 ? 41 VAL A N 1 ATOM 87 C CA . VAL A 1 41 ? 26.570 38.246 -8.190 1.00 10.31 ? 41 VAL A CA 1 ATOM 88 C C . VAL A 1 41 ? 25.241 38.228 -7.495 1.00 10.90 ? 41 VAL A C 1 ATOM 89 O O . VAL A 1 41 ? 24.183 38.288 -8.135 1.00 11.93 ? 41 VAL A O 1 ATOM 90 C CB . VAL A 1 41 ? 27.207 39.669 -8.110 1.00 9.94 ? 41 VAL A CB 1 ATOM 91 C CG1 . VAL A 1 41 ? 28.643 39.632 -8.526 1.00 11.77 ? 41 VAL A CG1 1 ATOM 92 C CG2 . VAL A 1 41 ? 26.427 40.663 -8.957 1.00 10.82 ? 41 VAL A CG2 1 ATOM 93 N N . ASP A 1 42 ? 25.243 38.171 -6.174 1.00 9.42 ? 42 ASP A N 1 ATOM 94 C CA . ASP A 1 42 ? 23.988 38.198 -5.447 1.00 9.02 ? 42 ASP A CA 1 ATOM 95 C C . ASP A 1 42 ? 23.292 39.546 -5.486 1.00 9.42 ? 42 ASP A C 1 ATOM 96 O O . ASP A 1 42 ? 22.084 39.640 -5.565 1.00 11.43 ? 42 ASP A O 1 ATOM 97 C CB . ASP A 1 42 ? 24.188 37.767 -3.990 1.00 9.81 ? 42 ASP A CB 1 ATOM 98 C CG . ASP A 1 42 ? 24.696 36.347 -3.876 1.00 12.55 ? 42 ASP A CG 1 ATOM 99 O OD1 . ASP A 1 42 ? 24.018 35.447 -4.389 1.00 16.23 ? 42 ASP A OD1 1 ATOM 100 O OD2 . ASP A 1 42 ? 25.750 36.107 -3.289 1.00 13.40 ? 42 ASP A OD2 1 ATOM 101 N N . VAL A 1 43 ? 24.086 40.598 -5.392 1.00 7.75 ? 43 VAL A N 1 ATOM 102 C CA . VAL A 1 43 ? 23.544 41.956 -5.423 1.00 7.96 ? 43 VAL A CA 1 ATOM 103 C C . VAL A 1 43 ? 24.308 42.711 -6.491 1.00 7.61 ? 43 VAL A C 1 ATOM 104 O O . VAL A 1 43 ? 25.542 42.814 -6.433 1.00 8.10 ? 43 VAL A O 1 ATOM 105 C CB . VAL A 1 43 ? 23.701 42.677 -4.094 1.00 7.97 ? 43 VAL A CB 1 ATOM 106 C CG1 . VAL A 1 43 ? 23.091 44.090 -4.196 1.00 9.74 ? 43 VAL A CG1 1 ATOM 107 C CG2 . VAL A 1 43 ? 22.996 41.836 -2.993 1.00 10.72 ? 43 VAL A CG2 1 ATOM 108 N N . GLN A 1 44 ? 23.600 43.204 -7.494 1.00 6.90 ? 44 GLN A N 1 ATOM 109 C CA . GLN A 1 44 ? 24.209 44.056 -8.517 1.00 7.29 ? 44 GLN A CA 1 ATOM 110 C C . GLN A 1 44 ? 23.502 45.392 -8.431 1.00 6.62 ? 44 GLN A C 1 ATOM 111 O O . GLN A 1 44 ? 22.298 45.466 -8.555 1.00 7.57 ? 44 GLN A O 1 ATOM 112 C CB . GLN A 1 44 ? 24.087 43.403 -9.910 1.00 8.21 ? 44 GLN A CB 1 ATOM 113 C CG . GLN A 1 44 ? 25.175 43.857 -10.888 1.00 6.55 ? 44 GLN A CG 1 ATOM 114 C CD . GLN A 1 44 ? 25.234 45.368 -11.021 1.00 7.77 ? 44 GLN A CD 1 ATOM 115 O OE1 . GLN A 1 44 ? 24.218 45.994 -11.365 1.00 9.00 ? 44 GLN A OE1 1 ATOM 116 N NE2 . GLN A 1 44 ? 26.414 45.957 -10.725 1.00 6.51 ? 44 GLN A NE2 1 ATOM 117 N N . MET A 1 45 ? 24.238 46.466 -8.086 1.00 6.25 ? 45 MET A N 1 ATOM 118 C CA . MET A 1 45 ? 23.538 47.671 -7.657 1.00 5.83 ? 45 MET A CA 1 ATOM 119 C C . MET A 1 45 ? 22.633 48.328 -8.718 1.00 6.32 ? 45 MET A C 1 ATOM 120 O O . MET A 1 45 ? 21.643 48.958 -8.345 1.00 6.98 ? 45 MET A O 1 ATOM 121 C CB . MET A 1 45 ? 24.536 48.686 -7.082 1.00 6.39 ? 45 MET A CB 1 ATOM 122 C CG . MET A 1 45 ? 25.171 48.238 -5.752 1.00 6.52 ? 45 MET A CG 1 ATOM 123 S SD . MET A 1 45 ? 23.956 47.960 -4.473 1.00 9.68 ? 45 MET A SD 1 ATOM 124 C CE . MET A 1 45 ? 23.225 49.636 -4.296 1.00 11.34 ? 45 MET A CE 1 ATOM 125 N N . LEU A 1 46 ? 23.013 48.216 -9.983 1.00 6.49 ? 46 LEU A N 1 ATOM 126 C CA . LEU A 1 46 ? 22.168 48.794 -11.043 1.00 7.09 ? 46 LEU A CA 1 ATOM 127 C C . LEU A 1 46 ? 20.839 48.008 -11.079 1.00 7.67 ? 46 LEU A C 1 ATOM 128 O O . LEU A 1 46 ? 19.766 48.607 -11.188 1.00 8.26 ? 46 LEU A O 1 ATOM 129 C CB . LEU A 1 46 ? 22.864 48.790 -12.376 1.00 8.68 ? 46 LEU A CB 1 ATOM 130 C CG . LEU A 1 46 ? 22.078 49.530 -13.465 1.00 8.80 ? 46 LEU A CG 1 ATOM 131 C CD1 . LEU A 1 46 ? 22.078 51.041 -13.218 1.00 9.81 ? 46 LEU A CD1 1 ATOM 132 C CD2 . LEU A 1 46 ? 22.614 49.174 -14.853 1.00 9.77 ? 46 LEU A CD2 1 ATOM 133 N N A GLU A 1 47 ? 20.929 46.693 -10.933 0.50 8.05 ? 47 GLU A N 1 ATOM 134 N N B GLU A 1 47 ? 20.923 46.682 -10.957 0.50 8.11 ? 47 GLU A N 1 ATOM 135 C CA A GLU A 1 47 ? 19.733 45.855 -10.970 0.50 8.97 ? 47 GLU A CA 1 ATOM 136 C CA B GLU A 1 47 ? 19.712 45.846 -10.969 0.50 8.94 ? 47 GLU A CA 1 ATOM 137 C C A GLU A 1 47 ? 18.897 46.070 -9.731 0.50 9.03 ? 47 GLU A C 1 ATOM 138 C C B GLU A 1 47 ? 18.889 46.140 -9.737 0.50 9.04 ? 47 GLU A C 1 ATOM 139 O O A GLU A 1 47 ? 17.673 46.103 -9.800 0.50 9.69 ? 47 GLU A O 1 ATOM 140 O O B GLU A 1 47 ? 17.668 46.277 -9.814 0.50 9.42 ? 47 GLU A O 1 ATOM 141 C CB A GLU A 1 47 ? 20.137 44.392 -11.109 0.50 9.51 ? 47 GLU A CB 1 ATOM 142 C CB B GLU A 1 47 ? 20.070 44.351 -11.013 0.50 9.65 ? 47 GLU A CB 1 ATOM 143 C CG A GLU A 1 47 ? 20.778 44.112 -12.448 0.50 11.16 ? 47 GLU A CG 1 ATOM 144 C CG B GLU A 1 47 ? 18.882 43.414 -11.266 0.50 10.98 ? 47 GLU A CG 1 ATOM 145 C CD A GLU A 1 47 ? 21.254 42.691 -12.618 0.50 15.23 ? 47 GLU A CD 1 ATOM 146 C CD B GLU A 1 47 ? 18.111 43.026 -10.006 0.50 16.67 ? 47 GLU A CD 1 ATOM 147 O OE1 A GLU A 1 47 ? 20.947 41.845 -11.755 0.50 17.94 ? 47 GLU A OE1 1 ATOM 148 O OE1 B GLU A 1 47 ? 18.671 43.131 -8.888 0.50 14.16 ? 47 GLU A OE1 1 ATOM 149 O OE2 A GLU A 1 47 ? 21.942 42.435 -13.629 0.50 14.52 ? 47 GLU A OE2 1 ATOM 150 O OE2 B GLU A 1 47 ? 16.925 42.606 -10.124 0.50 17.86 ? 47 GLU A OE2 1 ATOM 151 N N . LEU A 1 48 ? 19.557 46.265 -8.594 1.00 8.63 ? 48 LEU A N 1 ATOM 152 C CA . LEU A 1 48 ? 18.852 46.567 -7.356 1.00 9.20 ? 48 LEU A CA 1 ATOM 153 C C . LEU A 1 48 ? 18.113 47.875 -7.453 1.00 9.03 ? 48 LEU A C 1 ATOM 154 O O . LEU A 1 48 ? 16.926 47.948 -7.162 1.00 9.67 ? 48 LEU A O 1 ATOM 155 C CB . LEU A 1 48 ? 19.820 46.609 -6.165 1.00 9.12 ? 48 LEU A CB 1 ATOM 156 C CG . LEU A 1 48 ? 19.122 46.814 -4.821 1.00 11.05 ? 48 LEU A CG 1 ATOM 157 C CD1 . LEU A 1 48 ? 18.123 45.680 -4.538 1.00 16.35 ? 48 LEU A CD1 1 ATOM 158 C CD2 . LEU A 1 48 ? 20.125 46.972 -3.691 1.00 13.46 ? 48 LEU A CD2 1 ATOM 159 N N . TYR A 1 49 ? 18.789 48.893 -7.980 1.00 8.54 ? 49 TYR A N 1 ATOM 160 C CA . TYR A 1 49 ? 18.145 50.176 -8.207 1.00 7.96 ? 49 TYR A CA 1 ATOM 161 C C . TYR A 1 49 ? 16.907 50.074 -9.103 1.00 9.55 ? 49 TYR A C 1 ATOM 162 O O . TYR A 1 49 ? 15.896 50.735 -8.856 1.00 9.83 ? 49 TYR A O 1 ATOM 163 C CB . TYR A 1 49 ? 19.179 51.161 -8.788 1.00 7.85 ? 49 TYR A CB 1 ATOM 164 C CG . TYR A 1 49 ? 19.692 52.098 -7.733 1.00 9.07 ? 49 TYR A CG 1 ATOM 165 C CD1 . TYR A 1 49 ? 20.141 51.619 -6.489 1.00 8.02 ? 49 TYR A CD1 1 ATOM 166 C CD2 . TYR A 1 49 ? 19.704 53.476 -7.965 1.00 8.27 ? 49 TYR A CD2 1 ATOM 167 C CE1 . TYR A 1 49 ? 20.572 52.470 -5.512 1.00 9.31 ? 49 TYR A CE1 1 ATOM 168 C CE2 . TYR A 1 49 ? 20.148 54.365 -6.975 1.00 8.26 ? 49 TYR A CE2 1 ATOM 169 C CZ . TYR A 1 49 ? 20.576 53.841 -5.751 1.00 7.65 ? 49 TYR A CZ 1 ATOM 170 O OH . TYR A 1 49 ? 20.970 54.660 -4.729 1.00 8.15 ? 49 TYR A OH 1 ATOM 171 N N . ASP A 1 50 ? 16.974 49.218 -10.104 1.00 9.57 ? 50 ASP A N 1 ATOM 172 C CA . ASP A 1 50 ? 15.873 49.130 -11.059 1.00 13.22 ? 50 ASP A CA 1 ATOM 173 C C . ASP A 1 50 ? 14.636 48.567 -10.367 1.00 13.64 ? 50 ASP A C 1 ATOM 174 O O . ASP A 1 50 ? 13.503 48.938 -10.748 1.00 14.06 ? 50 ASP A O 1 ATOM 175 C CB . ASP A 1 50 ? 16.306 48.283 -12.244 1.00 13.32 ? 50 ASP A CB 1 ATOM 176 C CG . ASP A 1 50 ? 15.464 48.512 -13.474 1.00 18.66 ? 50 ASP A CG 1 ATOM 177 O OD1 . ASP A 1 50 ? 14.903 49.611 -13.634 1.00 21.67 ? 50 ASP A OD1 1 ATOM 178 O OD2 . ASP A 1 50 ? 15.350 47.646 -14.367 1.00 24.71 ? 50 ASP A OD2 1 ATOM 179 N N A ARG A 1 51 ? 14.837 47.679 -9.388 0.50 14.14 ? 51 ARG A N 1 ATOM 180 N N B ARG A 1 51 ? 14.825 47.729 -9.355 0.50 14.37 ? 51 ARG A N 1 ATOM 181 C CA A ARG A 1 51 ? 13.721 47.012 -8.696 0.50 14.67 ? 51 ARG A CA 1 ATOM 182 C CA B ARG A 1 51 ? 13.689 47.047 -8.740 0.50 15.08 ? 51 ARG A CA 1 ATOM 183 C C A ARG A 1 51 ? 13.205 47.726 -7.447 0.50 14.79 ? 51 ARG A C 1 ATOM 184 C C B ARG A 1 51 ? 13.302 47.519 -7.321 0.50 15.15 ? 51 ARG A C 1 ATOM 185 O O A ARG A 1 51 ? 12.013 47.646 -7.139 0.50 13.95 ? 51 ARG A O 1 ATOM 186 O O B ARG A 1 51 ? 12.280 47.089 -6.783 0.50 15.44 ? 51 ARG A O 1 ATOM 187 C CB A ARG A 1 51 ? 14.016 45.522 -8.406 0.50 15.12 ? 51 ARG A CB 1 ATOM 188 C CB B ARG A 1 51 ? 13.851 45.523 -8.861 0.50 15.85 ? 51 ARG A CB 1 ATOM 189 C CG A ARG A 1 51 ? 15.111 45.186 -7.416 0.50 15.81 ? 51 ARG A CG 1 ATOM 190 C CG B ARG A 1 51 ? 15.001 44.913 -8.092 0.50 16.23 ? 51 ARG A CG 1 ATOM 191 C CD A ARG A 1 51 ? 15.216 43.667 -7.129 0.50 16.26 ? 51 ARG A CD 1 ATOM 192 C CD B ARG A 1 51 ? 14.980 43.386 -8.119 0.50 16.16 ? 51 ARG A CD 1 ATOM 193 N NE A ARG A 1 51 ? 16.522 43.280 -6.599 0.50 19.53 ? 51 ARG A NE 1 ATOM 194 N NE B ARG A 1 51 ? 15.929 42.777 -7.194 0.50 18.84 ? 51 ARG A NE 1 ATOM 195 C CZ A ARG A 1 51 ? 17.567 42.931 -7.345 0.50 18.64 ? 51 ARG A CZ 1 ATOM 196 C CZ B ARG A 1 51 ? 15.750 42.675 -5.876 0.50 22.01 ? 51 ARG A CZ 1 ATOM 197 N NH1 A ARG A 1 51 ? 17.484 42.924 -8.668 0.50 19.31 ? 51 ARG A NH1 1 ATOM 198 N NH1 B ARG A 1 51 ? 14.660 43.161 -5.297 0.50 24.30 ? 51 ARG A NH1 1 ATOM 199 N NH2 A ARG A 1 51 ? 18.709 42.600 -6.768 0.50 20.98 ? 51 ARG A NH2 1 ATOM 200 N NH2 B ARG A 1 51 ? 16.678 42.088 -5.127 0.50 25.64 ? 51 ARG A NH2 1 ATOM 201 N N . MET A 1 52 ? 14.083 48.422 -6.743 1.00 14.86 ? 52 MET A N 1 ATOM 202 C CA A MET A 1 52 ? 13.732 49.050 -5.457 0.50 16.31 ? 52 MET A CA 1 ATOM 203 C CA B MET A 1 52 ? 13.742 49.045 -5.461 0.50 14.84 ? 52 MET A CA 1 ATOM 204 C C . MET A 1 52 ? 12.737 50.190 -5.560 1.00 15.17 ? 52 MET A C 1 ATOM 205 O O . MET A 1 52 ? 12.797 50.866 -6.536 1.00 16.58 ? 52 MET A O 1 ATOM 206 C CB A MET A 1 52 ? 15.002 49.623 -4.812 0.50 16.51 ? 52 MET A CB 1 ATOM 207 C CB B MET A 1 52 ? 14.994 49.717 -4.877 0.50 15.15 ? 52 MET A CB 1 ATOM 208 C CG A MET A 1 52 ? 15.836 48.627 -4.070 0.50 18.09 ? 52 MET A CG 1 ATOM 209 C CG B MET A 1 52 ? 15.924 48.833 -4.207 0.50 15.02 ? 52 MET A CG 1 ATOM 210 S SD A MET A 1 52 ? 17.232 49.482 -3.297 0.50 18.29 ? 52 MET A SD 1 ATOM 211 S SD B MET A 1 52 ? 17.373 49.830 -3.793 0.50 11.64 ? 52 MET A SD 1 ATOM 212 C CE A MET A 1 52 ? 16.364 50.467 -2.149 0.50 19.48 ? 52 MET A CE 1 ATOM 213 C CE B MET A 1 52 ? 16.685 50.959 -2.538 0.50 11.70 ? 52 MET A CE 1 ATOM 214 N N . SER A 1 53 ? 11.906 50.450 -4.555 1.00 16.90 ? 53 SER A N 1 ATOM 215 C CA . SER A 1 53 ? 10.885 51.514 -4.680 1.00 17.68 ? 53 SER A CA 1 ATOM 216 C C . SER A 1 53 ? 11.226 52.932 -4.102 1.00 17.36 ? 53 SER A C 1 ATOM 217 O O . SER A 1 53 ? 10.548 53.943 -4.381 1.00 19.52 ? 53 SER A O 1 ATOM 218 C CB . SER A 1 53 ? 9.549 51.017 -4.096 1.00 18.63 ? 53 SER A CB 1 ATOM 219 O OG . SER A 1 53 ? 9.431 51.422 -2.754 1.00 21.78 ? 53 SER A OG 1 ATOM 220 N N . PHE A 1 54 ? 12.242 52.966 -3.262 1.00 15.09 ? 54 PHE A N 1 ATOM 221 C CA . PHE A 1 54 ? 12.769 54.190 -2.637 1.00 13.81 ? 54 PHE A CA 1 ATOM 222 C C . PHE A 1 54 ? 11.742 54.986 -1.835 1.00 14.64 ? 54 PHE A C 1 ATOM 223 O O . PHE A 1 54 ? 11.896 56.185 -1.640 1.00 14.98 ? 54 PHE A O 1 ATOM 224 C CB . PHE A 1 54 ? 13.440 55.121 -3.674 1.00 12.98 ? 54 PHE A CB 1 ATOM 225 C CG . PHE A 1 54 ? 14.694 54.549 -4.295 1.00 10.19 ? 54 PHE A CG 1 ATOM 226 C CD1 . PHE A 1 54 ? 14.626 53.736 -5.413 1.00 11.85 ? 54 PHE A CD1 1 ATOM 227 C CD2 . PHE A 1 54 ? 15.934 54.824 -3.753 1.00 9.93 ? 54 PHE A CD2 1 ATOM 228 C CE1 . PHE A 1 54 ? 15.770 53.196 -5.975 1.00 10.28 ? 54 PHE A CE1 1 ATOM 229 C CE2 . PHE A 1 54 ? 17.078 54.291 -4.313 1.00 11.40 ? 54 PHE A CE2 1 ATOM 230 C CZ . PHE A 1 54 ? 16.997 53.490 -5.429 1.00 11.44 ? 54 PHE A CZ 1 ATOM 231 N N . LYS A 1 55 ? 10.679 54.334 -1.352 1.00 14.62 ? 55 LYS A N 1 ATOM 232 C CA . LYS A 1 55 ? 9.695 55.096 -0.569 1.00 16.43 ? 55 LYS A CA 1 ATOM 233 C C . LYS A 1 55 ? 10.276 55.479 0.775 1.00 16.04 ? 55 LYS A C 1 ATOM 234 O O . LYS A 1 55 ? 10.959 54.688 1.442 1.00 16.81 ? 55 LYS A O 1 ATOM 235 C CB . LYS A 1 55 ? 8.406 54.284 -0.349 1.00 17.34 ? 55 LYS A CB 1 ATOM 236 C CG . LYS A 1 55 ? 7.703 53.833 -1.609 1.00 20.20 ? 55 LYS A CG 1 ATOM 237 C CD . LYS A 1 55 ? 7.487 54.954 -2.556 1.00 19.16 ? 55 LYS A CD 1 ATOM 238 C CE . LYS A 1 55 ? 6.492 54.552 -3.621 1.00 23.57 ? 55 LYS A CE 1 ATOM 239 N NZ . LYS A 1 55 ? 6.353 55.614 -4.641 1.00 22.99 ? 55 LYS A NZ 1 ATOM 240 N N . ASP A 1 56 ? 10.015 56.713 1.169 1.00 15.50 ? 56 ASP A N 1 ATOM 241 C CA . ASP A 1 56 ? 10.558 57.256 2.394 1.00 15.33 ? 56 ASP A CA 1 ATOM 242 C C . ASP A 1 56 ? 9.485 57.177 3.489 1.00 16.48 ? 56 ASP A C 1 ATOM 243 O O . ASP A 1 56 ? 8.838 58.165 3.818 1.00 18.84 ? 56 ASP A O 1 ATOM 244 C CB . ASP A 1 56 ? 11.070 58.683 2.156 1.00 15.12 ? 56 ASP A CB 1 ATOM 245 C CG . ASP A 1 56 ? 11.689 59.309 3.390 1.00 15.67 ? 56 ASP A CG 1 ATOM 246 O OD1 . ASP A 1 56 ? 12.177 58.596 4.306 1.00 13.73 ? 56 ASP A OD1 1 ATOM 247 O OD2 . ASP A 1 56 ? 11.733 60.555 3.525 1.00 16.40 ? 56 ASP A OD2 1 ATOM 248 N N . ILE A 1 57 ? 9.323 55.991 4.052 1.00 17.87 ? 57 ILE A N 1 ATOM 249 C CA . ILE A 1 57 ? 8.291 55.814 5.064 1.00 19.13 ? 57 ILE A CA 1 ATOM 250 C C . ILE A 1 57 ? 8.897 55.838 6.458 1.00 18.90 ? 57 ILE A C 1 ATOM 251 O O . ILE A 1 57 ? 10.063 55.466 6.661 1.00 18.05 ? 57 ILE A O 1 ATOM 252 C CB . ILE A 1 57 ? 7.456 54.534 4.831 1.00 20.92 ? 57 ILE A CB 1 ATOM 253 C CG1 . ILE A 1 57 ? 8.280 53.284 5.067 1.00 23.38 ? 57 ILE A CG1 1 ATOM 254 C CG2 . ILE A 1 57 ? 6.798 54.517 3.434 1.00 21.58 ? 57 ILE A CG2 1 ATOM 255 C CD1 . ILE A 1 57 ? 7.458 52.144 5.641 1.00 26.78 ? 57 ILE A CD1 1 ATOM 256 N N . ASP A 1 58 ? 8.092 56.285 7.414 1.00 18.14 ? 58 ASP A N 1 ATOM 257 C CA . ASP A 1 58 ? 8.462 56.388 8.812 1.00 17.90 ? 58 ASP A CA 1 ATOM 258 C C . ASP A 1 58 ? 8.463 54.986 9.403 1.00 17.10 ? 58 ASP A C 1 ATOM 259 O O . ASP A 1 58 ? 7.404 54.385 9.589 1.00 17.76 ? 58 ASP A O 1 ATOM 260 C CB . ASP A 1 58 ? 7.430 57.262 9.536 1.00 18.90 ? 58 ASP A CB 1 ATOM 261 C CG . ASP A 1 58 ? 7.814 57.593 10.963 1.00 20.85 ? 58 ASP A CG 1 ATOM 262 O OD1 . ASP A 1 58 ? 8.633 56.871 11.589 1.00 20.37 ? 58 ASP A OD1 1 ATOM 263 O OD2 . ASP A 1 58 ? 7.329 58.587 11.566 1.00 28.51 ? 58 ASP A OD2 1 ATOM 264 N N . GLY A 1 59 ? 9.649 54.457 9.695 1.00 14.47 ? 59 GLY A N 1 ATOM 265 C CA . GLY A 1 59 ? 9.783 53.124 10.241 1.00 13.89 ? 59 GLY A CA 1 ATOM 266 C C . GLY A 1 59 ? 9.742 53.031 11.764 1.00 12.93 ? 59 GLY A C 1 ATOM 267 O O . GLY A 1 59 ? 10.000 51.958 12.277 1.00 13.79 ? 59 GLY A O 1 ATOM 268 N N . GLY A 1 60 ? 9.442 54.124 12.462 1.00 12.46 ? 60 GLY A N 1 ATOM 269 C CA . GLY A 1 60 ? 9.398 54.115 13.911 1.00 13.13 ? 60 GLY A CA 1 ATOM 270 C C . GLY A 1 60 ? 10.672 54.725 14.487 1.00 12.12 ? 60 GLY A C 1 ATOM 271 O O . GLY A 1 60 ? 11.194 55.680 13.927 1.00 13.19 ? 60 GLY A O 1 ATOM 272 N N . VAL A 1 61 ? 11.147 54.212 15.620 1.00 11.66 ? 61 VAL A N 1 ATOM 273 C CA . VAL A 1 61 ? 12.354 54.767 16.236 1.00 10.74 ? 61 VAL A CA 1 ATOM 274 C C . VAL A 1 61 ? 13.558 54.691 15.262 1.00 10.40 ? 61 VAL A C 1 ATOM 275 O O . VAL A 1 61 ? 14.381 55.611 15.194 1.00 10.21 ? 61 VAL A O 1 ATOM 276 C CB . VAL A 1 61 ? 12.703 54.108 17.575 1.00 12.20 ? 61 VAL A CB 1 ATOM 277 C CG1 . VAL A 1 61 ? 11.563 54.380 18.592 1.00 13.03 ? 61 VAL A CG1 1 ATOM 278 C CG2 . VAL A 1 61 ? 12.921 52.626 17.416 1.00 12.17 ? 61 VAL A CG2 1 ATOM 279 N N . TRP A 1 62 ? 13.623 53.612 14.496 1.00 9.54 ? 62 TRP A N 1 ATOM 280 C CA . TRP A 1 62 ? 14.580 53.540 13.396 1.00 9.18 ? 62 TRP A CA 1 ATOM 281 C C . TRP A 1 62 ? 13.822 54.170 12.244 1.00 9.86 ? 62 TRP A C 1 ATOM 282 O O . TRP A 1 62 ? 13.060 53.522 11.523 1.00 10.06 ? 62 TRP A O 1 ATOM 283 C CB . TRP A 1 62 ? 14.989 52.108 13.092 1.00 9.12 ? 62 TRP A CB 1 ATOM 284 C CG . TRP A 1 62 ? 15.959 52.005 11.950 1.00 8.55 ? 62 TRP A CG 1 ATOM 285 C CD1 . TRP A 1 62 ? 16.660 53.046 11.324 1.00 8.22 ? 62 TRP A CD1 1 ATOM 286 C CD2 . TRP A 1 62 ? 16.324 50.817 11.268 1.00 7.61 ? 62 TRP A CD2 1 ATOM 287 N NE1 . TRP A 1 62 ? 17.408 52.533 10.289 1.00 8.24 ? 62 TRP A NE1 1 ATOM 288 C CE2 . TRP A 1 62 ? 17.235 51.178 10.235 1.00 10.03 ? 62 TRP A CE2 1 ATOM 289 C CE3 . TRP A 1 62 ? 15.983 49.461 11.412 1.00 7.48 ? 62 TRP A CE3 1 ATOM 290 C CZ2 . TRP A 1 62 ? 17.775 50.258 9.364 1.00 8.98 ? 62 TRP A CZ2 1 ATOM 291 C CZ3 . TRP A 1 62 ? 16.519 48.546 10.543 1.00 7.31 ? 62 TRP A CZ3 1 ATOM 292 C CH2 . TRP A 1 62 ? 17.426 48.945 9.526 1.00 8.46 ? 62 TRP A CH2 1 ATOM 293 N N . LYS A 1 63 ? 14.034 55.468 12.048 1.00 9.67 ? 63 LYS A N 1 ATOM 294 C CA . LYS A 1 63 ? 13.145 56.242 11.165 1.00 11.01 ? 63 LYS A CA 1 ATOM 295 C C . LYS A 1 63 ? 13.119 55.734 9.739 1.00 11.03 ? 63 LYS A C 1 ATOM 296 O O . LYS A 1 63 ? 12.089 55.766 9.065 1.00 12.02 ? 63 LYS A O 1 ATOM 297 C CB . LYS A 1 63 ? 13.495 57.733 11.213 1.00 11.40 ? 63 LYS A CB 1 ATOM 298 C CG . LYS A 1 63 ? 12.953 58.451 12.441 1.00 15.80 ? 63 LYS A CG 1 ATOM 299 C CD . LYS A 1 63 ? 11.591 59.094 12.110 1.00 22.93 ? 63 LYS A CD 1 ATOM 300 C CE . LYS A 1 63 ? 10.765 59.397 13.332 1.00 27.18 ? 63 LYS A CE 1 ATOM 301 N NZ . LYS A 1 63 ? 9.828 58.261 13.580 1.00 29.08 ? 63 LYS A NZ 1 ATOM 302 N N . GLN A 1 64 ? 14.259 55.243 9.281 1.00 9.23 ? 64 GLN A N 1 ATOM 303 C CA . GLN A 1 64 ? 14.373 54.806 7.909 1.00 9.28 ? 64 GLN A CA 1 ATOM 304 C C . GLN A 1 64 ? 14.441 53.293 7.745 1.00 9.14 ? 64 GLN A C 1 ATOM 305 O O . GLN A 1 64 ? 14.777 52.792 6.677 1.00 8.70 ? 64 GLN A O 1 ATOM 306 C CB . GLN A 1 64 ? 15.612 55.472 7.303 1.00 8.77 ? 64 GLN A CB 1 ATOM 307 C CG . GLN A 1 64 ? 15.474 56.978 7.258 1.00 9.63 ? 64 GLN A CG 1 ATOM 308 C CD . GLN A 1 64 ? 16.830 57.651 7.119 1.00 9.82 ? 64 GLN A CD 1 ATOM 309 O OE1 . GLN A 1 64 ? 17.769 57.303 7.835 1.00 9.34 ? 64 GLN A OE1 1 ATOM 310 N NE2 . GLN A 1 64 ? 16.912 58.624 6.227 1.00 8.06 ? 64 GLN A NE2 1 ATOM 311 N N . GLY A 1 65 ? 14.067 52.560 8.806 1.00 9.31 ? 65 GLY A N 1 ATOM 312 C CA . GLY A 1 65 ? 14.019 51.106 8.769 1.00 8.78 ? 65 GLY A CA 1 ATOM 313 C C . GLY A 1 65 ? 12.669 50.556 9.209 1.00 9.74 ? 65 GLY A C 1 ATOM 314 O O . GLY A 1 65 ? 11.638 50.946 8.647 1.00 11.27 ? 65 GLY A O 1 ATOM 315 N N . TRP A 1 66 ? 12.696 49.658 10.196 1.00 10.58 ? 66 TRP A N 1 ATOM 316 C CA . TRP A 1 66 ? 11.450 49.053 10.716 1.00 11.18 ? 66 TRP A CA 1 ATOM 317 C C . TRP A 1 66 ? 11.713 48.698 12.156 1.00 11.69 ? 66 TRP A C 1 ATOM 318 O O . TRP A 1 66 ? 12.847 48.844 12.648 1.00 11.50 ? 66 TRP A O 1 ATOM 319 C CB . TRP A 1 66 ? 11.051 47.815 9.895 1.00 10.76 ? 66 TRP A CB 1 ATOM 320 C CG . TRP A 1 66 ? 11.997 46.653 10.051 1.00 11.17 ? 66 TRP A CG 1 ATOM 321 C CD1 . TRP A 1 66 ? 11.880 45.615 10.941 1.00 11.93 ? 66 TRP A CD1 1 ATOM 322 C CD2 . TRP A 1 66 ? 13.237 46.425 9.354 1.00 10.22 ? 66 TRP A CD2 1 ATOM 323 N NE1 . TRP A 1 66 ? 12.956 44.767 10.842 1.00 11.80 ? 66 TRP A NE1 1 ATOM 324 C CE2 . TRP A 1 66 ? 13.795 45.225 9.856 1.00 10.90 ? 66 TRP A CE2 1 ATOM 325 C CE3 . TRP A 1 66 ? 13.920 47.099 8.331 1.00 10.51 ? 66 TRP A CE3 1 ATOM 326 C CZ2 . TRP A 1 66 ? 15.001 44.689 9.379 1.00 11.44 ? 66 TRP A CZ2 1 ATOM 327 C CZ3 . TRP A 1 66 ? 15.129 46.562 7.862 1.00 10.71 ? 66 TRP A CZ3 1 ATOM 328 C CH2 . TRP A 1 66 ? 15.667 45.388 8.402 1.00 10.49 ? 66 TRP A CH2 1 ATOM 329 N N . ASN A 1 67 ? 10.668 48.258 12.877 1.00 12.64 ? 67 ASN A N 1 ATOM 330 C CA . ASN A 1 67 ? 10.827 47.830 14.263 1.00 12.54 ? 67 ASN A CA 1 ATOM 331 C C . ASN A 1 67 ? 11.434 46.427 14.294 1.00 12.75 ? 67 ASN A C 1 ATOM 332 O O . ASN A 1 67 ? 10.759 45.425 13.972 1.00 12.79 ? 67 ASN A O 1 ATOM 333 C CB . ASN A 1 67 ? 9.456 47.787 14.958 1.00 13.03 ? 67 ASN A CB 1 ATOM 334 C CG . ASN A 1 67 ? 8.881 49.146 15.232 1.00 18.15 ? 67 ASN A CG 1 ATOM 335 O OD1 . ASN A 1 67 ? 9.580 50.153 15.323 1.00 20.15 ? 67 ASN A OD1 1 ATOM 336 N ND2 . ASN A 1 67 ? 7.562 49.172 15.406 1.00 20.06 ? 67 ASN A ND2 1 ATOM 337 N N . ILE A 1 68 ? 12.709 46.347 14.649 1.00 11.30 ? 68 ILE A N 1 ATOM 338 C CA . ILE A 1 68 ? 13.433 45.096 14.586 1.00 12.05 ? 68 ILE A CA 1 ATOM 339 C C . ILE A 1 68 ? 12.986 44.199 15.728 1.00 13.15 ? 68 ILE A C 1 ATOM 340 O O . ILE A 1 68 ? 12.941 44.648 16.869 1.00 13.48 ? 68 ILE A O 1 ATOM 341 C CB . ILE A 1 68 ? 14.994 45.304 14.668 1.00 11.39 ? 68 ILE A CB 1 ATOM 342 C CG1 . ILE A 1 68 ? 15.526 46.137 13.488 1.00 11.96 ? 68 ILE A CG1 1 ATOM 343 C CG2 . ILE A 1 68 ? 15.675 43.962 14.681 1.00 13.53 ? 68 ILE A CG2 1 ATOM 344 C CD1 . ILE A 1 68 ? 16.976 46.598 13.699 1.00 11.60 ? 68 ILE A CD1 1 ATOM 345 N N . LYS A 1 69 ? 12.743 42.929 15.404 1.00 14.65 ? 69 LYS A N 1 ATOM 346 C CA . LYS A 1 69 ? 12.389 41.930 16.422 1.00 15.38 ? 69 LYS A CA 1 ATOM 347 C C . LYS A 1 69 ? 13.461 40.862 16.434 1.00 15.19 ? 69 LYS A C 1 ATOM 348 O O . LYS A 1 69 ? 14.043 40.554 15.409 1.00 15.18 ? 69 LYS A O 1 ATOM 349 C CB . LYS A 1 69 ? 11.039 41.296 16.071 1.00 17.01 ? 69 LYS A CB 1 ATOM 350 C CG . LYS A 1 69 ? 9.892 42.294 16.038 1.00 19.70 ? 69 LYS A CG 1 ATOM 351 C CD . LYS A 1 69 ? 8.739 41.797 15.146 1.00 28.55 ? 69 LYS A CD 1 ATOM 352 C CE . LYS A 1 69 ? 7.907 40.698 15.826 1.00 32.29 ? 69 LYS A CE 1 ATOM 353 N NZ . LYS A 1 69 ? 6.752 40.250 14.977 1.00 35.19 ? 69 LYS A NZ 1 ATOM 354 N N . TYR A 1 70 ? 13.693 40.271 17.597 1.00 15.31 ? 70 TYR A N 1 ATOM 355 C CA . TYR A 1 70 ? 14.638 39.167 17.676 1.00 15.14 ? 70 TYR A CA 1 ATOM 356 C C . TYR A 1 70 ? 14.097 38.094 18.596 1.00 16.25 ? 70 TYR A C 1 ATOM 357 O O . TYR A 1 70 ? 13.255 38.382 19.453 1.00 16.76 ? 70 TYR A O 1 ATOM 358 C CB . TYR A 1 70 ? 16.026 39.625 18.161 1.00 15.39 ? 70 TYR A CB 1 ATOM 359 C CG . TYR A 1 70 ? 16.057 40.258 19.521 1.00 14.02 ? 70 TYR A CG 1 ATOM 360 C CD1 . TYR A 1 70 ? 15.878 41.614 19.663 1.00 14.60 ? 70 TYR A CD1 1 ATOM 361 C CD2 . TYR A 1 70 ? 16.272 39.489 20.675 1.00 14.16 ? 70 TYR A CD2 1 ATOM 362 C CE1 . TYR A 1 70 ? 15.921 42.221 20.894 1.00 13.96 ? 70 TYR A CE1 1 ATOM 363 C CE2 . TYR A 1 70 ? 16.290 40.073 21.915 1.00 14.62 ? 70 TYR A CE2 1 ATOM 364 C CZ . TYR A 1 70 ? 16.122 41.450 22.027 1.00 14.11 ? 70 TYR A CZ 1 ATOM 365 O OH . TYR A 1 70 ? 16.128 42.062 23.265 1.00 17.78 ? 70 TYR A OH 1 ATOM 366 N N . ASP A 1 71 ? 14.603 36.881 18.406 1.00 17.83 ? 71 ASP A N 1 ATOM 367 C CA . ASP A 1 71 ? 14.253 35.750 19.264 1.00 19.01 ? 71 ASP A CA 1 ATOM 368 C C . ASP A 1 71 ? 15.223 35.731 20.432 1.00 19.27 ? 71 ASP A C 1 ATOM 369 O O . ASP A 1 71 ? 16.405 35.522 20.222 1.00 18.00 ? 71 ASP A O 1 ATOM 370 C CB . ASP A 1 71 ? 14.390 34.457 18.471 1.00 19.86 ? 71 ASP A CB 1 ATOM 371 C CG . ASP A 1 71 ? 13.850 33.237 19.226 1.00 22.99 ? 71 ASP A CG 1 ATOM 372 O OD1 . ASP A 1 71 ? 13.640 33.302 20.463 1.00 26.08 ? 71 ASP A OD1 1 ATOM 373 O OD2 . ASP A 1 71 ? 13.605 32.177 18.620 1.00 27.49 ? 71 ASP A OD2 1 ATOM 374 N N . PRO A 1 72 ? 14.745 35.923 21.661 1.00 20.78 ? 72 PRO A N 1 ATOM 375 C CA . PRO A 1 72 ? 15.638 35.909 22.825 1.00 21.69 ? 72 PRO A CA 1 ATOM 376 C C . PRO A 1 72 ? 16.410 34.583 22.949 1.00 22.06 ? 72 PRO A C 1 ATOM 377 O O . PRO A 1 72 ? 17.549 34.556 23.424 1.00 23.24 ? 72 PRO A O 1 ATOM 378 C CB . PRO A 1 72 ? 14.691 36.127 24.014 1.00 22.35 ? 72 PRO A CB 1 ATOM 379 C CG . PRO A 1 72 ? 13.436 36.693 23.426 1.00 22.83 ? 72 PRO A CG 1 ATOM 380 C CD . PRO A 1 72 ? 13.338 36.173 22.036 1.00 20.91 ? 72 PRO A CD 1 ATOM 381 N N . LEU A 1 73 ? 15.826 33.503 22.435 1.00 22.06 ? 73 LEU A N 1 ATOM 382 C CA . LEU A 1 73 ? 16.437 32.177 22.520 1.00 21.96 ? 73 LEU A CA 1 ATOM 383 C C . LEU A 1 73 ? 17.543 31.933 21.494 1.00 20.96 ? 73 LEU A C 1 ATOM 384 O O . LEU A 1 73 ? 18.194 30.885 21.503 1.00 20.22 ? 73 LEU A O 1 ATOM 385 C CB . LEU A 1 73 ? 15.359 31.087 22.406 1.00 22.61 ? 73 LEU A CB 1 ATOM 386 C CG . LEU A 1 73 ? 14.287 31.052 23.500 1.00 25.01 ? 73 LEU A CG 1 ATOM 387 C CD1 . LEU A 1 73 ? 13.382 29.846 23.269 1.00 26.46 ? 73 LEU A CD1 1 ATOM 388 C CD2 . LEU A 1 73 ? 14.927 30.987 24.888 1.00 25.93 ? 73 LEU A CD2 1 ATOM 389 N N . LYS A 1 74 ? 17.773 32.917 20.623 1.00 19.42 ? 74 LYS A N 1 ATOM 390 C CA . LYS A 1 74 ? 18.828 32.814 19.624 1.00 19.00 ? 74 LYS A CA 1 ATOM 391 C C . LYS A 1 74 ? 20.221 32.660 20.225 1.00 18.34 ? 74 LYS A C 1 ATOM 392 O O . LYS A 1 74 ? 21.037 31.892 19.720 1.00 19.08 ? 74 LYS A O 1 ATOM 393 C CB . LYS A 1 74 ? 18.817 34.015 18.676 1.00 18.98 ? 74 LYS A CB 1 ATOM 394 C CG . LYS A 1 74 ? 19.921 33.936 17.626 1.00 20.59 ? 74 LYS A CG 1 ATOM 395 C CD . LYS A 1 74 ? 19.819 35.097 16.627 1.00 22.26 ? 74 LYS A CD 1 ATOM 396 C CE . LYS A 1 74 ? 20.663 34.822 15.385 1.00 24.11 ? 74 LYS A CE 1 ATOM 397 N NZ . LYS A 1 74 ? 20.412 35.831 14.299 1.00 27.13 ? 74 LYS A NZ 1 ATOM 398 N N A TYR A 1 75 ? 20.517 33.429 21.273 0.50 17.89 ? 75 TYR A N 1 ATOM 399 N N B TYR A 1 75 ? 20.476 33.398 21.293 0.50 18.19 ? 75 TYR A N 1 ATOM 400 C CA A TYR A 1 75 ? 21.805 33.318 21.969 0.50 17.39 ? 75 TYR A CA 1 ATOM 401 C CA B TYR A 1 75 ? 21.722 33.253 22.017 0.50 17.97 ? 75 TYR A CA 1 ATOM 402 C C A TYR A 1 75 ? 21.615 32.622 23.325 0.50 18.04 ? 75 TYR A C 1 ATOM 403 C C B TYR A 1 75 ? 21.474 32.386 23.224 0.50 18.19 ? 75 TYR A C 1 ATOM 404 O O A TYR A 1 75 ? 20.666 32.922 24.052 0.50 18.70 ? 75 TYR A O 1 ATOM 405 O O B TYR A 1 75 ? 20.367 32.328 23.754 0.50 18.21 ? 75 TYR A O 1 ATOM 406 C CB A TYR A 1 75 ? 22.515 34.688 22.086 0.50 16.59 ? 75 TYR A CB 1 ATOM 407 C CB B TYR A 1 75 ? 22.263 34.612 22.426 0.50 17.64 ? 75 TYR A CB 1 ATOM 408 C CG A TYR A 1 75 ? 22.813 35.287 20.721 0.50 13.80 ? 75 TYR A CG 1 ATOM 409 C CG B TYR A 1 75 ? 22.250 35.555 21.265 0.50 16.42 ? 75 TYR A CG 1 ATOM 410 C CD1 A TYR A 1 75 ? 23.818 34.760 19.917 0.50 13.43 ? 75 TYR A CD1 1 ATOM 411 C CD1 B TYR A 1 75 ? 23.208 35.464 20.259 0.50 13.97 ? 75 TYR A CD1 1 ATOM 412 C CD2 A TYR A 1 75 ? 22.055 36.350 20.209 0.50 13.94 ? 75 TYR A CD2 1 ATOM 413 C CD2 B TYR A 1 75 ? 21.254 36.508 21.147 0.50 16.66 ? 75 TYR A CD2 1 ATOM 414 C CE1 A TYR A 1 75 ? 24.066 35.269 18.647 0.50 13.74 ? 75 TYR A CE1 1 ATOM 415 C CE1 B TYR A 1 75 ? 23.170 36.324 19.166 0.50 15.04 ? 75 TYR A CE1 1 ATOM 416 C CE2 A TYR A 1 75 ? 22.301 36.866 18.934 0.50 13.92 ? 75 TYR A CE2 1 ATOM 417 C CE2 B TYR A 1 75 ? 21.204 37.359 20.076 0.50 15.62 ? 75 TYR A CE2 1 ATOM 418 C CZ A TYR A 1 75 ? 23.312 36.315 18.167 0.50 13.32 ? 75 TYR A CZ 1 ATOM 419 C CZ B TYR A 1 75 ? 22.156 37.275 19.097 0.50 16.21 ? 75 TYR A CZ 1 ATOM 420 O OH A TYR A 1 75 ? 23.575 36.808 16.899 0.50 12.46 ? 75 TYR A OH 1 ATOM 421 O OH B TYR A 1 75 ? 22.062 38.157 18.063 0.50 17.56 ? 75 TYR A OH 1 ATOM 422 N N . ASN A 1 76 ? 22.516 31.686 23.626 1.00 18.44 ? 76 ASN A N 1 ATOM 423 C CA . ASN A 1 76 ? 22.449 30.840 24.815 1.00 20.46 ? 76 ASN A CA 1 ATOM 424 C C . ASN A 1 76 ? 23.860 30.541 25.289 1.00 21.13 ? 76 ASN A C 1 ATOM 425 O O . ASN A 1 76 ? 24.830 31.052 24.728 1.00 21.12 ? 76 ASN A O 1 ATOM 426 C CB . ASN A 1 76 ? 21.659 29.548 24.532 1.00 21.30 ? 76 ASN A CB 1 ATOM 427 C CG . ASN A 1 76 ? 22.200 28.763 23.349 1.00 21.57 ? 76 ASN A CG 1 ATOM 428 O OD1 . ASN A 1 76 ? 23.402 28.538 23.222 1.00 24.11 ? 76 ASN A OD1 1 ATOM 429 N ND2 . ASN A 1 76 ? 21.293 28.321 22.480 1.00 26.94 ? 76 ASN A ND2 1 ATOM 430 N N . ALA A 1 77 ? 23.988 29.703 26.319 1.00 23.22 ? 77 ALA A N 1 ATOM 431 C CA . ALA A 1 77 ? 25.303 29.375 26.872 1.00 24.58 ? 77 ALA A CA 1 ATOM 432 C C . ALA A 1 77 ? 26.291 28.907 25.802 1.00 24.85 ? 77 ALA A C 1 ATOM 433 O O . ALA A 1 77 ? 27.485 29.183 25.883 1.00 25.59 ? 77 ALA A O 1 ATOM 434 C CB . ALA A 1 77 ? 25.171 28.313 27.972 1.00 25.10 ? 77 ALA A CB 1 ATOM 435 N N . HIS A 1 78 ? 25.788 28.219 24.785 1.00 25.61 ? 78 HIS A N 1 ATOM 436 C CA . HIS A 1 78 ? 26.677 27.600 23.800 1.00 26.04 ? 78 HIS A CA 1 ATOM 437 C C . HIS A 1 78 ? 26.949 28.509 22.601 1.00 24.78 ? 78 HIS A C 1 ATOM 438 O O . HIS A 1 78 ? 27.832 28.230 21.779 1.00 25.86 ? 78 HIS A O 1 ATOM 439 C CB . HIS A 1 78 ? 26.129 26.229 23.368 1.00 27.07 ? 78 HIS A CB 1 ATOM 440 C CG . HIS A 1 78 ? 25.740 25.349 24.520 1.00 30.47 ? 78 HIS A CG 1 ATOM 441 N ND1 . HIS A 1 78 ? 26.621 25.003 25.524 1.00 33.93 ? 78 HIS A ND1 1 ATOM 442 C CD2 . HIS A 1 78 ? 24.564 24.749 24.827 1.00 32.83 ? 78 HIS A CD2 1 ATOM 443 C CE1 . HIS A 1 78 ? 26.005 24.227 26.401 1.00 34.50 ? 78 HIS A CE1 1 ATOM 444 N NE2 . HIS A 1 78 ? 24.755 24.058 26.001 1.00 35.34 ? 78 HIS A NE2 1 ATOM 445 N N . HIS A 1 79 ? 26.211 29.617 22.540 1.00 22.39 ? 79 HIS A N 1 ATOM 446 C CA . HIS A 1 79 ? 26.233 30.501 21.378 1.00 19.55 ? 79 HIS A CA 1 ATOM 447 C C . HIS A 1 79 ? 25.967 31.918 21.859 1.00 16.79 ? 79 HIS A C 1 ATOM 448 O O . HIS A 1 79 ? 24.825 32.358 21.928 1.00 16.97 ? 79 HIS A O 1 ATOM 449 C CB . HIS A 1 79 ? 25.150 30.063 20.397 1.00 19.30 ? 79 HIS A CB 1 ATOM 450 C CG . HIS A 1 79 ? 25.144 30.833 19.110 1.00 19.92 ? 79 HIS A CG 1 ATOM 451 N ND1 . HIS A 1 79 ? 26.138 30.714 18.163 1.00 22.91 ? 79 HIS A ND1 1 ATOM 452 C CD2 . HIS A 1 79 ? 24.248 31.717 18.611 1.00 20.12 ? 79 HIS A CD2 1 ATOM 453 C CE1 . HIS A 1 79 ? 25.864 31.511 17.143 1.00 19.66 ? 79 HIS A CE1 1 ATOM 454 N NE2 . HIS A 1 79 ? 24.729 32.139 17.395 1.00 21.17 ? 79 HIS A NE2 1 ATOM 455 N N . LYS A 1 80 ? 27.031 32.593 22.256 1.00 15.59 ? 80 LYS A N 1 ATOM 456 C CA . LYS A 1 80 ? 26.890 33.926 22.830 1.00 14.38 ? 80 LYS A CA 1 ATOM 457 C C . LYS A 1 80 ? 27.058 34.998 21.757 1.00 13.77 ? 80 LYS A C 1 ATOM 458 O O . LYS A 1 80 ? 27.665 34.756 20.723 1.00 14.67 ? 80 LYS A O 1 ATOM 459 C CB . LYS A 1 80 ? 27.914 34.150 23.916 1.00 15.14 ? 80 LYS A CB 1 ATOM 460 C CG . LYS A 1 80 ? 27.810 33.146 25.063 1.00 18.61 ? 80 LYS A CG 1 ATOM 461 C CD . LYS A 1 80 ? 29.038 33.252 25.912 1.00 24.29 ? 80 LYS A CD 1 ATOM 462 C CE . LYS A 1 80 ? 28.981 34.467 26.806 1.00 25.23 ? 80 LYS A CE 1 ATOM 463 N NZ . LYS A 1 80 ? 30.003 34.327 27.902 1.00 26.99 ? 80 LYS A NZ 1 ATOM 464 N N . LEU A 1 81 ? 26.457 36.151 21.995 1.00 11.39 ? 81 LEU A N 1 ATOM 465 C CA . LEU A 1 81 ? 26.721 37.332 21.128 1.00 10.53 ? 81 LEU A CA 1 ATOM 466 C C . LEU A 1 81 ? 28.017 37.991 21.598 1.00 10.66 ? 81 LEU A C 1 ATOM 467 O O . LEU A 1 81 ? 28.114 38.434 22.753 1.00 10.03 ? 81 LEU A O 1 ATOM 468 C CB . LEU A 1 81 ? 25.586 38.348 21.246 1.00 10.04 ? 81 LEU A CB 1 ATOM 469 C CG . LEU A 1 81 ? 25.666 39.602 20.338 1.00 10.92 ? 81 LEU A CG 1 ATOM 470 C CD1 . LEU A 1 81 ? 25.751 39.246 18.829 1.00 12.19 ? 81 LEU A CD1 1 ATOM 471 C CD2 . LEU A 1 81 ? 24.516 40.570 20.636 1.00 13.29 ? 81 LEU A CD2 1 ATOM 472 N N . LYS A 1 82 ? 28.999 38.072 20.716 1.00 8.96 ? 82 LYS A N 1 ATOM 473 C CA A LYS A 1 82 ? 30.284 38.707 21.042 0.50 8.38 ? 82 LYS A CA 1 ATOM 474 C CA B LYS A 1 82 ? 30.264 38.707 21.040 0.50 8.81 ? 82 LYS A CA 1 ATOM 475 C C . LYS A 1 82 ? 30.222 40.141 20.541 1.00 8.97 ? 82 LYS A C 1 ATOM 476 O O . LYS A 1 82 ? 30.024 40.337 19.356 1.00 9.98 ? 82 LYS A O 1 ATOM 477 C CB A LYS A 1 82 ? 31.432 37.948 20.367 0.50 8.77 ? 82 LYS A CB 1 ATOM 478 C CB B LYS A 1 82 ? 31.433 37.957 20.392 0.50 9.30 ? 82 LYS A CB 1 ATOM 479 C CG A LYS A 1 82 ? 31.601 36.511 20.863 0.50 9.31 ? 82 LYS A CG 1 ATOM 480 C CG B LYS A 1 82 ? 32.798 38.601 20.659 0.50 12.23 ? 82 LYS A CG 1 ATOM 481 C CD A LYS A 1 82 ? 32.098 35.599 19.742 0.50 15.36 ? 82 LYS A CD 1 ATOM 482 C CD B LYS A 1 82 ? 33.024 38.841 22.153 0.50 16.26 ? 82 LYS A CD 1 ATOM 483 C CE A LYS A 1 82 ? 33.543 35.875 19.373 0.50 17.84 ? 82 LYS A CE 1 ATOM 484 C CE B LYS A 1 82 ? 34.448 38.494 22.532 0.50 18.47 ? 82 LYS A CE 1 ATOM 485 N NZ A LYS A 1 82 ? 34.050 34.906 18.367 0.50 18.64 ? 82 LYS A NZ 1 ATOM 486 N NZ B LYS A 1 82 ? 35.094 37.783 21.401 0.50 18.97 ? 82 LYS A NZ 1 ATOM 487 N N . VAL A 1 83 ? 30.385 41.104 21.450 1.00 7.45 ? 83 VAL A N 1 ATOM 488 C CA . VAL A 1 83 ? 30.220 42.521 21.081 1.00 7.37 ? 83 VAL A CA 1 ATOM 489 C C . VAL A 1 83 ? 31.556 43.248 21.234 1.00 8.06 ? 83 VAL A C 1 ATOM 490 O O . VAL A 1 83 ? 32.169 43.242 22.308 1.00 8.75 ? 83 VAL A O 1 ATOM 491 C CB . VAL A 1 83 ? 29.183 43.196 21.990 1.00 7.66 ? 83 VAL A CB 1 ATOM 492 C CG1 . VAL A 1 83 ? 29.005 44.677 21.655 1.00 9.51 ? 83 VAL A CG1 1 ATOM 493 C CG2 . VAL A 1 83 ? 27.832 42.498 21.834 1.00 9.47 ? 83 VAL A CG2 1 ATOM 494 N N . PHE A 1 84 ? 32.002 43.888 20.149 1.00 7.52 ? 84 PHE A N 1 ATOM 495 C CA . PHE A 1 84 ? 33.219 44.718 20.163 1.00 8.25 ? 84 PHE A CA 1 ATOM 496 C C . PHE A 1 84 ? 32.836 46.162 20.089 1.00 7.09 ? 84 PHE A C 1 ATOM 497 O O . PHE A 1 84 ? 32.305 46.613 19.073 1.00 7.55 ? 84 PHE A O 1 ATOM 498 C CB . PHE A 1 84 ? 34.119 44.358 18.980 1.00 9.27 ? 84 PHE A CB 1 ATOM 499 C CG . PHE A 1 84 ? 34.740 43.008 19.113 1.00 10.02 ? 84 PHE A CG 1 ATOM 500 C CD1 . PHE A 1 84 ? 35.787 42.822 20.009 1.00 12.90 ? 84 PHE A CD1 1 ATOM 501 C CD2 . PHE A 1 84 ? 34.249 41.916 18.410 1.00 12.42 ? 84 PHE A CD2 1 ATOM 502 C CE1 . PHE A 1 84 ? 36.388 41.567 20.169 1.00 13.01 ? 84 PHE A CE1 1 ATOM 503 C CE2 . PHE A 1 84 ? 34.835 40.661 18.562 1.00 14.91 ? 84 PHE A CE2 1 ATOM 504 C CZ . PHE A 1 84 ? 35.929 40.491 19.417 1.00 13.62 ? 84 PHE A CZ 1 ATOM 505 N N . VAL A 1 85 ? 33.098 46.885 21.174 1.00 5.87 ? 85 VAL A N 1 ATOM 506 C CA . VAL A 1 85 ? 32.876 48.315 21.240 1.00 6.34 ? 85 VAL A CA 1 ATOM 507 C C . VAL A 1 85 ? 34.182 48.968 20.838 1.00 5.93 ? 85 VAL A C 1 ATOM 508 O O . VAL A 1 85 ? 35.196 48.767 21.498 1.00 6.50 ? 85 VAL A O 1 ATOM 509 C CB . VAL A 1 85 ? 32.439 48.737 22.663 1.00 6.14 ? 85 VAL A CB 1 ATOM 510 C CG1 . VAL A 1 85 ? 32.262 50.245 22.746 1.00 9.49 ? 85 VAL A CG1 1 ATOM 511 C CG2 . VAL A 1 85 ? 31.124 48.066 22.990 1.00 7.99 ? 85 VAL A CG2 1 ATOM 512 N N . VAL A 1 86 ? 34.154 49.752 19.738 1.00 6.28 ? 86 VAL A N 1 ATOM 513 C CA . VAL A 1 86 ? 35.384 50.251 19.145 1.00 6.64 ? 86 VAL A CA 1 ATOM 514 C C . VAL A 1 86 ? 35.459 51.774 19.262 1.00 5.91 ? 86 VAL A C 1 ATOM 515 O O . VAL A 1 86 ? 34.803 52.492 18.469 1.00 5.72 ? 86 VAL A O 1 ATOM 516 C CB . VAL A 1 86 ? 35.458 49.816 17.654 1.00 6.68 ? 86 VAL A CB 1 ATOM 517 C CG1 . VAL A 1 86 ? 36.748 50.376 17.002 1.00 8.47 ? 86 VAL A CG1 1 ATOM 518 C CG2 . VAL A 1 86 ? 35.403 48.274 17.564 1.00 8.56 ? 86 VAL A CG2 1 ATOM 519 N N . PRO A 1 87 ? 36.218 52.294 20.219 1.00 5.37 ? 87 PRO A N 1 ATOM 520 C CA . PRO A 1 87 ? 36.293 53.763 20.388 1.00 5.85 ? 87 PRO A CA 1 ATOM 521 C C . PRO A 1 87 ? 37.029 54.396 19.206 1.00 5.87 ? 87 PRO A C 1 ATOM 522 O O . PRO A 1 87 ? 38.039 53.841 18.709 1.00 5.79 ? 87 PRO A O 1 ATOM 523 C CB . PRO A 1 87 ? 37.109 53.938 21.668 1.00 6.01 ? 87 PRO A CB 1 ATOM 524 C CG . PRO A 1 87 ? 36.877 52.582 22.418 1.00 6.32 ? 87 PRO A CG 1 ATOM 525 C CD . PRO A 1 87 ? 36.923 51.563 21.302 1.00 6.49 ? 87 PRO A CD 1 ATOM 526 N N . HIS A 1 88 ? 36.530 55.566 18.791 1.00 4.82 ? 88 HIS A N 1 ATOM 527 C CA . HIS A 1 88 ? 37.109 56.248 17.610 1.00 5.28 ? 88 HIS A CA 1 ATOM 528 C C . HIS A 1 88 ? 36.845 57.743 17.703 1.00 5.71 ? 88 HIS A C 1 ATOM 529 O O . HIS A 1 88 ? 36.033 58.202 18.506 1.00 5.86 ? 88 HIS A O 1 ATOM 530 C CB . HIS A 1 88 ? 36.542 55.657 16.316 1.00 5.68 ? 88 HIS A CB 1 ATOM 531 C CG . HIS A 1 88 ? 35.105 55.971 16.067 1.00 5.82 ? 88 HIS A CG 1 ATOM 532 N ND1 . HIS A 1 88 ? 34.701 57.017 15.255 1.00 5.74 ? 88 HIS A ND1 1 ATOM 533 C CD2 . HIS A 1 88 ? 33.970 55.359 16.490 1.00 6.40 ? 88 HIS A CD2 1 ATOM 534 C CE1 . HIS A 1 88 ? 33.376 57.028 15.194 1.00 6.10 ? 88 HIS A CE1 1 ATOM 535 N NE2 . HIS A 1 88 ? 32.915 56.038 15.943 1.00 8.50 ? 88 HIS A NE2 1 ATOM 536 N N . SER A 1 89 ? 37.562 58.502 16.880 1.00 4.87 ? 89 SER A N 1 ATOM 537 C CA . SER A 1 89 ? 37.487 59.942 16.873 1.00 6.64 ? 89 SER A CA 1 ATOM 538 C C . SER A 1 89 ? 37.661 60.389 15.426 1.00 6.38 ? 89 SER A C 1 ATOM 539 O O . SER A 1 89 ? 38.722 60.177 14.865 1.00 6.45 ? 89 SER A O 1 ATOM 540 C CB . SER A 1 89 ? 38.607 60.503 17.745 1.00 7.03 ? 89 SER A CB 1 ATOM 541 O OG . SER A 1 89 ? 38.547 61.914 17.701 1.00 7.25 ? 89 SER A OG 1 ATOM 542 N N . HIS A 1 90 ? 36.625 60.969 14.851 1.00 5.87 ? 90 HIS A N 1 ATOM 543 C CA . HIS A 1 90 ? 36.670 61.363 13.437 1.00 5.72 ? 90 HIS A CA 1 ATOM 544 C C . HIS A 1 90 ? 37.332 62.745 13.363 1.00 5.83 ? 90 HIS A C 1 ATOM 545 O O . HIS A 1 90 ? 36.812 63.718 13.901 1.00 6.24 ? 90 HIS A O 1 ATOM 546 C CB . HIS A 1 90 ? 35.278 61.371 12.839 1.00 7.27 ? 90 HIS A CB 1 ATOM 547 C CG . HIS A 1 90 ? 35.272 61.698 11.385 1.00 5.32 ? 90 HIS A CG 1 ATOM 548 N ND1 . HIS A 1 90 ? 35.844 60.878 10.427 1.00 6.81 ? 90 HIS A ND1 1 ATOM 549 C CD2 . HIS A 1 90 ? 34.766 62.763 10.726 1.00 6.91 ? 90 HIS A CD2 1 ATOM 550 C CE1 . HIS A 1 90 ? 35.646 61.428 9.229 1.00 6.05 ? 90 HIS A CE1 1 ATOM 551 N NE2 . HIS A 1 90 ? 35.012 62.580 9.383 1.00 6.52 ? 90 HIS A NE2 1 ATOM 552 N N . ASN A 1 91 ? 38.518 62.808 12.758 1.00 6.18 ? 91 ASN A N 1 ATOM 553 C CA . ASN A 1 91 ? 39.309 64.044 12.729 1.00 6.54 ? 91 ASN A CA 1 ATOM 554 C C . ASN A 1 91 ? 39.469 64.494 11.288 1.00 7.60 ? 91 ASN A C 1 ATOM 555 O O . ASN A 1 91 ? 40.352 64.012 10.560 1.00 8.97 ? 91 ASN A O 1 ATOM 556 C CB . ASN A 1 91 ? 40.707 63.803 13.332 1.00 7.25 ? 91 ASN A CB 1 ATOM 557 C CG . ASN A 1 91 ? 40.686 63.783 14.861 1.00 7.76 ? 91 ASN A CG 1 ATOM 558 O OD1 . ASN A 1 91 ? 41.309 64.621 15.542 1.00 7.93 ? 91 ASN A OD1 1 ATOM 559 N ND2 . ASN A 1 91 ? 39.982 62.823 15.404 1.00 7.39 ? 91 ASN A ND2 1 ATOM 560 N N . ASP A 1 92 ? 38.684 65.463 10.882 1.00 6.70 ? 92 ASP A N 1 ATOM 561 C CA . ASP A 1 92 ? 38.782 66.004 9.524 1.00 6.88 ? 92 ASP A CA 1 ATOM 562 C C . ASP A 1 92 ? 40.036 66.837 9.351 1.00 6.54 ? 92 ASP A C 1 ATOM 563 O O . ASP A 1 92 ? 40.213 67.804 10.094 1.00 6.84 ? 92 ASP A O 1 ATOM 564 C CB . ASP A 1 92 ? 37.595 66.911 9.289 1.00 7.00 ? 92 ASP A CB 1 ATOM 565 C CG . ASP A 1 92 ? 36.334 66.160 9.177 1.00 8.92 ? 92 ASP A CG 1 ATOM 566 O OD1 . ASP A 1 92 ? 36.305 65.181 8.411 1.00 9.14 ? 92 ASP A OD1 1 ATOM 567 O OD2 . ASP A 1 92 ? 35.333 66.466 9.845 1.00 14.27 ? 92 ASP A OD2 1 ATOM 568 N N . PRO A 1 93 ? 40.894 66.519 8.376 1.00 6.34 ? 93 PRO A N 1 ATOM 569 C CA . PRO A 1 93 ? 42.044 67.370 8.025 1.00 6.29 ? 93 PRO A CA 1 ATOM 570 C C . PRO A 1 93 ? 41.651 68.633 7.269 1.00 7.58 ? 93 PRO A C 1 ATOM 571 O O . PRO A 1 93 ? 42.054 68.851 6.124 1.00 9.14 ? 93 PRO A O 1 ATOM 572 C CB . PRO A 1 93 ? 42.941 66.448 7.166 1.00 7.13 ? 93 PRO A CB 1 ATOM 573 C CG . PRO A 1 93 ? 42.384 65.056 7.337 1.00 9.94 ? 93 PRO A CG 1 ATOM 574 C CD . PRO A 1 93 ? 40.895 65.242 7.640 1.00 5.90 ? 93 PRO A CD 1 ATOM 575 N N . GLY A 1 94 ? 40.915 69.467 7.981 1.00 6.27 ? 94 GLY A N 1 ATOM 576 C CA . GLY A 1 94 ? 40.338 70.679 7.414 1.00 6.22 ? 94 GLY A CA 1 ATOM 577 C C . GLY A 1 94 ? 38.848 70.462 7.131 1.00 6.92 ? 94 GLY A C 1 ATOM 578 O O . GLY A 1 94 ? 38.418 69.411 6.596 1.00 7.58 ? 94 GLY A O 1 ATOM 579 N N . TRP A 1 95 ? 38.061 71.426 7.549 1.00 6.33 ? 95 TRP A N 1 ATOM 580 C CA . TRP A 1 95 ? 36.632 71.454 7.244 1.00 6.13 ? 95 TRP A CA 1 ATOM 581 C C . TRP A 1 95 ? 36.084 72.828 7.661 1.00 7.42 ? 95 TRP A C 1 ATOM 582 O O . TRP A 1 95 ? 36.004 73.752 6.836 1.00 7.14 ? 95 TRP A O 1 ATOM 583 C CB . TRP A 1 95 ? 35.841 70.316 7.934 1.00 6.72 ? 95 TRP A CB 1 ATOM 584 C CG . TRP A 1 95 ? 34.360 70.385 7.570 1.00 6.73 ? 95 TRP A CG 1 ATOM 585 C CD1 . TRP A 1 95 ? 33.819 70.797 6.391 1.00 6.75 ? 95 TRP A CD1 1 ATOM 586 C CD2 . TRP A 1 95 ? 33.271 69.992 8.390 1.00 8.18 ? 95 TRP A CD2 1 ATOM 587 N NE1 . TRP A 1 95 ? 32.445 70.722 6.446 1.00 7.51 ? 95 TRP A NE1 1 ATOM 588 C CE2 . TRP A 1 95 ? 32.083 70.242 7.671 1.00 7.59 ? 95 TRP A CE2 1 ATOM 589 C CE3 . TRP A 1 95 ? 33.169 69.481 9.693 1.00 11.53 ? 95 TRP A CE3 1 ATOM 590 C CZ2 . TRP A 1 95 ? 30.795 69.939 8.194 1.00 9.26 ? 95 TRP A CZ2 1 ATOM 591 C CZ3 . TRP A 1 95 ? 31.887 69.213 10.218 1.00 11.34 ? 95 TRP A CZ3 1 ATOM 592 C CH2 . TRP A 1 95 ? 30.730 69.438 9.469 1.00 11.88 ? 95 TRP A CH2 1 ATOM 593 N N . ILE A 1 96 ? 35.770 72.987 8.947 1.00 7.10 ? 96 ILE A N 1 ATOM 594 C CA A ILE A 1 96 ? 35.330 74.247 9.581 0.50 8.85 ? 96 ILE A CA 1 ATOM 595 C CA B ILE A 1 96 ? 35.367 74.315 9.388 0.50 8.16 ? 96 ILE A CA 1 ATOM 596 C C . ILE A 1 96 ? 36.505 75.069 10.082 1.00 8.68 ? 96 ILE A C 1 ATOM 597 O O . ILE A 1 96 ? 36.375 76.255 10.357 1.00 10.80 ? 96 ILE A O 1 ATOM 598 C CB A ILE A 1 96 ? 34.426 73.960 10.825 0.50 9.57 ? 96 ILE A CB 1 ATOM 599 C CB B ILE A 1 96 ? 34.007 74.310 10.165 0.50 7.50 ? 96 ILE A CB 1 ATOM 600 C CG1 A ILE A 1 96 ? 33.162 73.175 10.476 0.50 11.37 ? 96 ILE A CG1 1 ATOM 601 C CG1 B ILE A 1 96 ? 34.089 73.557 11.488 0.50 9.51 ? 96 ILE A CG1 1 ATOM 602 C CG2 A ILE A 1 96 ? 34.076 75.239 11.574 0.50 9.90 ? 96 ILE A CG2 1 ATOM 603 C CG2 B ILE A 1 96 ? 32.929 73.661 9.299 0.50 8.47 ? 96 ILE A CG2 1 ATOM 604 C CD1 A ILE A 1 96 ? 32.405 73.678 9.283 0.50 13.32 ? 96 ILE A CD1 1 ATOM 605 C CD1 B ILE A 1 96 ? 33.016 73.989 12.477 0.50 12.63 ? 96 ILE A CD1 1 ATOM 606 N N A GLN A 1 97 ? 37.629 74.393 10.298 0.50 6.96 ? 97 GLN A N 1 ATOM 607 N N B GLN A 1 97 ? 37.611 74.367 10.319 0.50 7.23 ? 97 GLN A N 1 ATOM 608 C CA A GLN A 1 97 ? 38.901 75.015 10.620 0.50 6.87 ? 97 GLN A CA 1 ATOM 609 C CA B GLN A 1 97 ? 38.904 74.957 10.630 0.50 7.46 ? 97 GLN A CA 1 ATOM 610 C C A GLN A 1 97 ? 39.951 74.419 9.689 0.50 6.32 ? 97 GLN A C 1 ATOM 611 C C B GLN A 1 97 ? 39.955 74.407 9.673 0.50 6.69 ? 97 GLN A C 1 ATOM 612 O O A GLN A 1 97 ? 39.687 73.403 9.025 0.50 6.24 ? 97 GLN A O 1 ATOM 613 O O B GLN A 1 97 ? 39.703 73.408 8.984 0.50 6.47 ? 97 GLN A O 1 ATOM 614 C CB A GLN A 1 97 ? 39.287 74.730 12.080 0.50 7.11 ? 97 GLN A CB 1 ATOM 615 C CB B GLN A 1 97 ? 39.309 74.610 12.063 0.50 8.18 ? 97 GLN A CB 1 ATOM 616 C CG A GLN A 1 97 ? 38.166 74.975 13.107 0.50 7.36 ? 97 GLN A CG 1 ATOM 617 C CG B GLN A 1 97 ? 38.421 75.242 13.114 0.50 11.16 ? 97 GLN A CG 1 ATOM 618 C CD A GLN A 1 97 ? 38.661 74.894 14.556 0.50 7.74 ? 97 GLN A CD 1 ATOM 619 C CD B GLN A 1 97 ? 38.710 76.713 13.293 0.50 16.18 ? 97 GLN A CD 1 ATOM 620 O OE1 A GLN A 1 97 ? 39.827 75.166 14.844 0.50 12.32 ? 97 GLN A OE1 1 ATOM 621 O OE1 B GLN A 1 97 ? 39.426 77.094 14.213 0.50 19.06 ? 97 GLN A OE1 1 ATOM 622 N NE2 A GLN A 1 97 ? 37.781 74.491 15.451 0.50 11.47 ? 97 GLN A NE2 1 ATOM 623 N NE2 B GLN A 1 97 ? 38.177 77.543 12.406 0.50 17.73 ? 97 GLN A NE2 1 ATOM 624 N N . THR A 1 98 ? 41.120 75.028 9.611 1.00 6.61 ? 98 THR A N 1 ATOM 625 C CA . THR A 1 98 ? 42.186 74.455 8.799 1.00 6.00 ? 98 THR A CA 1 ATOM 626 C C . THR A 1 98 ? 42.797 73.246 9.493 1.00 5.92 ? 98 THR A C 1 ATOM 627 O O . THR A 1 98 ? 42.568 73.047 10.667 1.00 5.91 ? 98 THR A O 1 ATOM 628 C CB . THR A 1 98 ? 43.298 75.439 8.538 1.00 6.61 ? 98 THR A CB 1 ATOM 629 O OG1 . THR A 1 98 ? 43.886 75.808 9.782 1.00 8.07 ? 98 THR A OG1 1 ATOM 630 C CG2 . THR A 1 98 ? 42.754 76.700 7.859 1.00 7.77 ? 98 THR A CG2 1 ATOM 631 N N . PHE A 1 99 ? 43.567 72.465 8.745 1.00 5.58 ? 99 PHE A N 1 ATOM 632 C CA . PHE A 1 99 ? 44.335 71.380 9.328 1.00 6.00 ? 99 PHE A CA 1 ATOM 633 C C . PHE A 1 99 ? 45.100 71.863 10.539 1.00 6.58 ? 99 PHE A C 1 ATOM 634 O O . PHE A 1 99 ? 45.026 71.261 11.595 1.00 7.23 ? 99 PHE A O 1 ATOM 635 C CB . PHE A 1 99 ? 45.283 70.812 8.268 1.00 7.12 ? 99 PHE A CB 1 ATOM 636 C CG . PHE A 1 99 ? 46.162 69.707 8.767 1.00 7.12 ? 99 PHE A CG 1 ATOM 637 C CD1 . PHE A 1 99 ? 47.396 70.009 9.325 1.00 7.72 ? 99 PHE A CD1 1 ATOM 638 C CD2 . PHE A 1 99 ? 45.777 68.359 8.630 1.00 6.39 ? 99 PHE A CD2 1 ATOM 639 C CE1 . PHE A 1 99 ? 48.223 69.003 9.816 1.00 9.00 ? 99 PHE A CE1 1 ATOM 640 C CE2 . PHE A 1 99 ? 46.578 67.345 9.096 1.00 7.33 ? 99 PHE A CE2 1 ATOM 641 C CZ . PHE A 1 99 ? 47.825 67.659 9.673 1.00 7.63 ? 99 PHE A CZ 1 ATOM 642 N N . GLU A 1 100 ? 45.849 72.943 10.409 1.00 6.67 ? 100 GLU A N 1 ATOM 643 C CA . GLU A 1 100 ? 46.686 73.360 11.530 1.00 7.72 ? 100 GLU A CA 1 ATOM 644 C C . GLU A 1 100 ? 45.861 73.899 12.682 1.00 7.53 ? 100 GLU A C 1 ATOM 645 O O . GLU A 1 100 ? 46.206 73.639 13.845 1.00 7.93 ? 100 GLU A O 1 ATOM 646 C CB . GLU A 1 100 ? 47.729 74.398 11.102 1.00 9.08 ? 100 GLU A CB 1 ATOM 647 C CG . GLU A 1 100 ? 48.736 74.734 12.214 1.00 12.11 ? 100 GLU A CG 1 ATOM 648 C CD . GLU A 1 100 ? 49.629 73.574 12.636 1.00 14.03 ? 100 GLU A CD 1 ATOM 649 O OE1 . GLU A 1 100 ? 49.752 72.548 11.900 1.00 13.38 ? 100 GLU A OE1 1 ATOM 650 O OE2 . GLU A 1 100 ? 50.249 73.712 13.730 1.00 17.56 ? 100 GLU A OE2 1 ATOM 651 N N . GLU A 1 101 ? 44.741 74.572 12.405 1.00 6.88 ? 101 GLU A N 1 ATOM 652 C CA . GLU A 1 101 ? 43.877 75.011 13.489 1.00 8.82 ? 101 GLU A CA 1 ATOM 653 C C . GLU A 1 101 ? 43.281 73.860 14.257 1.00 8.19 ? 101 GLU A C 1 ATOM 654 O O . GLU A 1 101 ? 43.273 73.862 15.494 1.00 8.64 ? 101 GLU A O 1 ATOM 655 C CB . GLU A 1 101 ? 42.745 75.874 12.944 1.00 8.52 ? 101 GLU A CB 1 ATOM 656 C CG . GLU A 1 101 ? 43.176 77.280 12.543 1.00 12.78 ? 101 GLU A CG 1 ATOM 657 C CD . GLU A 1 101 ? 42.148 78.018 11.670 1.00 14.23 ? 101 GLU A CD 1 ATOM 658 O OE1 . GLU A 1 101 ? 41.176 77.434 11.125 1.00 10.75 ? 101 GLU A OE1 1 ATOM 659 O OE2 . GLU A 1 101 ? 42.308 79.261 11.524 1.00 18.61 ? 101 GLU A OE2 1 ATOM 660 N N . TYR A 1 102 ? 42.734 72.871 13.569 1.00 7.13 ? 102 TYR A N 1 ATOM 661 C CA . TYR A 1 102 ? 42.236 71.701 14.267 1.00 7.07 ? 102 TYR A CA 1 ATOM 662 C C . TYR A 1 102 ? 43.349 70.972 15.022 1.00 6.78 ? 102 TYR A C 1 ATOM 663 O O . TYR A 1 102 ? 43.115 70.431 16.090 1.00 7.40 ? 102 TYR A O 1 ATOM 664 C CB . TYR A 1 102 ? 41.669 70.717 13.264 1.00 6.47 ? 102 TYR A CB 1 ATOM 665 C CG . TYR A 1 102 ? 40.251 70.907 12.801 1.00 5.91 ? 102 TYR A CG 1 ATOM 666 C CD1 . TYR A 1 102 ? 39.208 71.154 13.678 1.00 6.55 ? 102 TYR A CD1 1 ATOM 667 C CD2 . TYR A 1 102 ? 39.950 70.768 11.471 1.00 5.82 ? 102 TYR A CD2 1 ATOM 668 C CE1 . TYR A 1 102 ? 37.907 71.262 13.211 1.00 7.16 ? 102 TYR A CE1 1 ATOM 669 C CE2 . TYR A 1 102 ? 38.694 70.856 11.019 1.00 6.30 ? 102 TYR A CE2 1 ATOM 670 C CZ . TYR A 1 102 ? 37.673 71.111 11.874 1.00 6.38 ? 102 TYR A CZ 1 ATOM 671 O OH . TYR A 1 102 ? 36.414 71.216 11.366 1.00 8.27 ? 102 TYR A OH 1 ATOM 672 N N . TYR A 1 103 ? 44.534 70.905 14.432 1.00 6.83 ? 103 TYR A N 1 ATOM 673 C CA . TYR A 1 103 ? 45.606 70.227 15.138 1.00 7.59 ? 103 TYR A CA 1 ATOM 674 C C . TYR A 1 103 ? 45.895 70.902 16.462 1.00 8.12 ? 103 TYR A C 1 ATOM 675 O O . TYR A 1 103 ? 46.043 70.222 17.492 1.00 8.11 ? 103 TYR A O 1 ATOM 676 C CB . TYR A 1 103 ? 46.865 70.148 14.279 1.00 8.40 ? 103 TYR A CB 1 ATOM 677 C CG . TYR A 1 103 ? 47.992 69.505 15.036 1.00 7.80 ? 103 TYR A CG 1 ATOM 678 C CD1 . TYR A 1 103 ? 48.011 68.138 15.299 1.00 8.57 ? 103 TYR A CD1 1 ATOM 679 C CD2 . TYR A 1 103 ? 49.029 70.296 15.534 1.00 7.60 ? 103 TYR A CD2 1 ATOM 680 C CE1 . TYR A 1 103 ? 49.028 67.575 16.033 1.00 8.57 ? 103 TYR A CE1 1 ATOM 681 C CE2 . TYR A 1 103 ? 50.052 69.743 16.283 1.00 8.40 ? 103 TYR A CE2 1 ATOM 682 C CZ . TYR A 1 103 ? 50.038 68.390 16.536 1.00 7.86 ? 103 TYR A CZ 1 ATOM 683 O OH . TYR A 1 103 ? 51.044 67.789 17.276 1.00 10.14 ? 103 TYR A OH 1 ATOM 684 N N . GLN A 1 104 ? 45.963 72.223 16.440 1.00 8.74 ? 104 GLN A N 1 ATOM 685 C CA . GLN A 1 104 ? 46.303 72.953 17.662 1.00 9.61 ? 104 GLN A CA 1 ATOM 686 C C . GLN A 1 104 ? 45.184 72.952 18.669 1.00 10.56 ? 104 GLN A C 1 ATOM 687 O O . GLN A 1 104 ? 45.452 72.890 19.888 1.00 12.06 ? 104 GLN A O 1 ATOM 688 C CB . GLN A 1 104 ? 46.666 74.403 17.319 1.00 10.02 ? 104 GLN A CB 1 ATOM 689 C CG . GLN A 1 104 ? 47.979 74.536 16.580 1.00 11.20 ? 104 GLN A CG 1 ATOM 690 C CD . GLN A 1 104 ? 49.166 74.037 17.393 1.00 12.58 ? 104 GLN A CD 1 ATOM 691 O OE1 . GLN A 1 104 ? 49.159 74.086 18.628 1.00 14.66 ? 104 GLN A OE1 1 ATOM 692 N NE2 . GLN A 1 104 ? 50.184 73.572 16.704 1.00 13.19 ? 104 GLN A NE2 1 ATOM 693 N N A HIS A 1 105 ? 43.940 73.035 18.207 0.50 10.24 ? 105 HIS A N 1 ATOM 694 N N B HIS A 1 105 ? 43.948 73.065 18.211 0.50 10.61 ? 105 HIS A N 1 ATOM 695 C CA A HIS A 1 105 ? 42.767 73.191 19.093 0.50 10.31 ? 105 HIS A CA 1 ATOM 696 C CA B HIS A 1 105 ? 42.829 73.170 19.143 0.50 11.06 ? 105 HIS A CA 1 ATOM 697 C C A HIS A 1 105 ? 42.138 71.884 19.543 0.50 10.43 ? 105 HIS A C 1 ATOM 698 C C B HIS A 1 105 ? 42.391 71.826 19.674 0.50 10.84 ? 105 HIS A C 1 ATOM 699 O O A HIS A 1 105 ? 41.412 71.856 20.540 0.50 10.80 ? 105 HIS A O 1 ATOM 700 O O B HIS A 1 105 ? 42.079 71.721 20.866 0.50 10.55 ? 105 HIS A O 1 ATOM 701 C CB A HIS A 1 105 ? 41.674 74.014 18.406 0.50 11.54 ? 105 HIS A CB 1 ATOM 702 C CB B HIS A 1 105 ? 41.631 73.875 18.517 0.50 12.60 ? 105 HIS A CB 1 ATOM 703 C CG A HIS A 1 105 ? 42.119 75.376 17.983 0.50 12.15 ? 105 HIS A CG 1 ATOM 704 C CG B HIS A 1 105 ? 40.675 74.416 19.531 0.50 15.85 ? 105 HIS A CG 1 ATOM 705 N ND1 A HIS A 1 105 ? 41.568 76.034 16.906 0.50 14.03 ? 105 HIS A ND1 1 ATOM 706 N ND1 B HIS A 1 105 ? 39.500 73.777 19.865 0.50 19.21 ? 105 HIS A ND1 1 ATOM 707 C CD2 A HIS A 1 105 ? 43.072 76.194 18.481 0.50 14.43 ? 105 HIS A CD2 1 ATOM 708 C CD2 B HIS A 1 105 ? 40.740 75.517 20.316 0.50 19.51 ? 105 HIS A CD2 1 ATOM 709 C CE1 A HIS A 1 105 ? 42.159 77.207 16.764 0.50 15.50 ? 105 HIS A CE1 1 ATOM 710 C CE1 B HIS A 1 105 ? 38.870 74.475 20.794 0.50 19.37 ? 105 HIS A CE1 1 ATOM 711 N NE2 A HIS A 1 105 ? 43.080 77.328 17.706 0.50 15.15 ? 105 HIS A NE2 1 ATOM 712 N NE2 B HIS A 1 105 ? 39.601 75.536 21.084 0.50 22.28 ? 105 HIS A NE2 1 ATOM 713 N N . ASP A 1 106 ? 42.389 70.811 18.795 1.00 9.99 ? 106 ASP A N 1 ATOM 714 C CA . ASP A 1 106 ? 41.743 69.531 19.083 1.00 10.27 ? 106 ASP A CA 1 ATOM 715 C C . ASP A 1 106 ? 42.649 68.322 18.993 1.00 8.69 ? 106 ASP A C 1 ATOM 716 O O . ASP A 1 106 ? 42.839 67.618 19.987 1.00 8.66 ? 106 ASP A O 1 ATOM 717 C CB . ASP A 1 106 ? 40.529 69.329 18.156 1.00 10.87 ? 106 ASP A CB 1 ATOM 718 C CG . ASP A 1 106 ? 39.488 70.384 18.359 1.00 15.98 ? 106 ASP A CG 1 ATOM 719 O OD1 . ASP A 1 106 ? 38.687 70.229 19.307 1.00 18.27 ? 106 ASP A OD1 1 ATOM 720 O OD2 . ASP A 1 106 ? 39.423 71.397 17.616 1.00 19.72 ? 106 ASP A OD2 1 ATOM 721 N N . THR A 1 107 ? 43.189 68.061 17.807 1.00 7.98 ? 107 THR A N 1 ATOM 722 C CA . THR A 1 107 ? 43.785 66.764 17.529 1.00 7.06 ? 107 THR A CA 1 ATOM 723 C C . THR A 1 107 ? 45.011 66.493 18.367 1.00 7.81 ? 107 THR A C 1 ATOM 724 O O . THR A 1 107 ? 45.228 65.361 18.784 1.00 6.33 ? 107 THR A O 1 ATOM 725 C CB . THR A 1 107 ? 44.079 66.629 16.022 1.00 7.69 ? 107 THR A CB 1 ATOM 726 O OG1 . THR A 1 107 ? 42.843 66.877 15.334 1.00 8.67 ? 107 THR A OG1 1 ATOM 727 C CG2 . THR A 1 107 ? 44.564 65.182 15.646 1.00 8.29 ? 107 THR A CG2 1 ATOM 728 N N . LYS A 1 108 ? 45.825 67.505 18.618 1.00 6.86 ? 108 LYS A N 1 ATOM 729 C CA . LYS A 1 108 ? 47.024 67.217 19.394 1.00 7.85 ? 108 LYS A CA 1 ATOM 730 C C . LYS A 1 108 ? 46.648 66.789 20.805 1.00 7.37 ? 108 LYS A C 1 ATOM 731 O O . LYS A 1 108 ? 47.341 65.967 21.404 1.00 8.19 ? 108 LYS A O 1 ATOM 732 C CB . LYS A 1 108 ? 48.010 68.401 19.393 1.00 8.06 ? 108 LYS A CB 1 ATOM 733 C CG . LYS A 1 108 ? 47.716 69.547 20.317 1.00 11.14 ? 108 LYS A CG 1 ATOM 734 C CD . LYS A 1 108 ? 48.838 70.585 20.225 1.00 11.13 ? 108 LYS A CD 1 ATOM 735 C CE . LYS A 1 108 ? 48.516 71.776 21.087 1.00 15.56 ? 108 LYS A CE 1 ATOM 736 N NZ . LYS A 1 108 ? 49.626 72.786 20.947 1.00 16.09 ? 108 LYS A NZ 1 ATOM 737 N N . HIS A 1 109 ? 45.545 67.335 21.299 1.00 7.51 ? 109 HIS A N 1 ATOM 738 C CA . HIS A 1 109 ? 45.027 66.954 22.631 1.00 8.00 ? 109 HIS A CA 1 ATOM 739 C C . HIS A 1 109 ? 44.415 65.583 22.633 1.00 8.08 ? 109 HIS A C 1 ATOM 740 O O . HIS A 1 109 ? 44.642 64.789 23.540 1.00 7.70 ? 109 HIS A O 1 ATOM 741 C CB . HIS A 1 109 ? 44.041 68.004 23.130 1.00 9.29 ? 109 HIS A CB 1 ATOM 742 C CG . HIS A 1 109 ? 44.653 69.358 23.201 1.00 11.22 ? 109 HIS A CG 1 ATOM 743 N ND1 . HIS A 1 109 ? 45.684 69.654 24.070 1.00 17.15 ? 109 HIS A ND1 1 ATOM 744 C CD2 . HIS A 1 109 ? 44.466 70.459 22.440 1.00 14.64 ? 109 HIS A CD2 1 ATOM 745 C CE1 . HIS A 1 109 ? 46.059 70.909 23.879 1.00 15.78 ? 109 HIS A CE1 1 ATOM 746 N NE2 . HIS A 1 109 ? 45.333 71.420 22.900 1.00 16.38 ? 109 HIS A NE2 1 ATOM 747 N N . ILE A 1 110 ? 43.669 65.244 21.588 1.00 7.42 ? 110 ILE A N 1 ATOM 748 C CA . ILE A 1 110 ? 43.151 63.884 21.469 1.00 7.09 ? 110 ILE A CA 1 ATOM 749 C C . ILE A 1 110 ? 44.270 62.854 21.471 1.00 6.85 ? 110 ILE A C 1 ATOM 750 O O . ILE A 1 110 ? 44.200 61.853 22.182 1.00 7.61 ? 110 ILE A O 1 ATOM 751 C CB . ILE A 1 110 ? 42.305 63.772 20.157 1.00 7.02 ? 110 ILE A CB 1 ATOM 752 C CG1 . ILE A 1 110 ? 41.092 64.699 20.241 1.00 6.39 ? 110 ILE A CG1 1 ATOM 753 C CG2 . ILE A 1 110 ? 41.941 62.314 19.812 1.00 7.32 ? 110 ILE A CG2 1 ATOM 754 C CD1 . ILE A 1 110 ? 40.390 64.969 18.889 1.00 7.70 ? 110 ILE A CD1 1 ATOM 755 N N . LEU A 1 111 ? 45.266 63.060 20.627 1.00 6.72 ? 111 LEU A N 1 ATOM 756 C CA . LEU A 1 111 ? 46.320 62.086 20.532 1.00 6.44 ? 111 LEU A CA 1 ATOM 757 C C . LEU A 1 111 ? 47.188 61.996 21.788 1.00 6.79 ? 111 LEU A C 1 ATOM 758 O O . LEU A 1 111 ? 47.578 60.921 22.203 1.00 7.36 ? 111 LEU A O 1 ATOM 759 C CB . LEU A 1 111 ? 47.171 62.355 19.277 1.00 7.64 ? 111 LEU A CB 1 ATOM 760 C CG . LEU A 1 111 ? 46.419 62.050 17.995 1.00 7.91 ? 111 LEU A CG 1 ATOM 761 C CD1 . LEU A 1 111 ? 47.255 62.540 16.854 1.00 9.12 ? 111 LEU A CD1 1 ATOM 762 C CD2 . LEU A 1 111 ? 46.247 60.562 17.933 1.00 9.57 ? 111 LEU A CD2 1 ATOM 763 N N . SER A 1 112 ? 47.441 63.135 22.415 1.00 6.95 ? 112 SER A N 1 ATOM 764 C CA A SER A 1 112 ? 48.235 63.118 23.632 0.50 8.38 ? 112 SER A CA 1 ATOM 765 C CA B SER A 1 112 ? 48.192 63.202 23.672 0.50 8.75 ? 112 SER A CA 1 ATOM 766 C C . SER A 1 112 ? 47.454 62.447 24.767 1.00 8.84 ? 112 SER A C 1 ATOM 767 O O . SER A 1 112 ? 48.028 61.662 25.542 1.00 9.65 ? 112 SER A O 1 ATOM 768 C CB A SER A 1 112 ? 48.671 64.532 24.002 0.50 8.63 ? 112 SER A CB 1 ATOM 769 C CB B SER A 1 112 ? 48.345 64.668 24.099 0.50 9.08 ? 112 SER A CB 1 ATOM 770 O OG A SER A 1 112 ? 49.344 64.536 25.245 0.50 10.25 ? 112 SER A OG 1 ATOM 771 O OG B SER A 1 112 ? 49.233 65.337 23.237 0.50 12.34 ? 112 SER A OG 1 ATOM 772 N N . ASN A 1 113 ? 46.153 62.698 24.845 1.00 8.62 ? 113 ASN A N 1 ATOM 773 C CA . ASN A 1 113 ? 45.366 62.068 25.895 1.00 9.00 ? 113 ASN A CA 1 ATOM 774 C C . ASN A 1 113 ? 45.099 60.608 25.577 1.00 8.89 ? 113 ASN A C 1 ATOM 775 O O . ASN A 1 113 ? 45.029 59.780 26.503 1.00 9.34 ? 113 ASN A O 1 ATOM 776 C CB . ASN A 1 113 ? 44.128 62.895 26.227 1.00 9.38 ? 113 ASN A CB 1 ATOM 777 C CG . ASN A 1 113 ? 44.505 64.214 26.884 1.00 11.79 ? 113 ASN A CG 1 ATOM 778 O OD1 . ASN A 1 113 ? 45.596 64.344 27.489 1.00 17.14 ? 113 ASN A OD1 1 ATOM 779 N ND2 . ASN A 1 113 ? 43.661 65.200 26.744 1.00 12.69 ? 113 ASN A ND2 1 ATOM 780 N N . ALA A 1 114 ? 45.033 60.229 24.291 1.00 8.53 ? 114 ALA A N 1 ATOM 781 C CA . ALA A 1 114 ? 44.919 58.817 23.941 1.00 9.12 ? 114 ALA A CA 1 ATOM 782 C C . ALA A 1 114 ? 46.161 58.062 24.395 1.00 8.88 ? 114 ALA A C 1 ATOM 783 O O . ALA A 1 114 ? 46.088 56.939 24.942 1.00 9.31 ? 114 ALA A O 1 ATOM 784 C CB . ALA A 1 114 ? 44.735 58.632 22.432 1.00 9.01 ? 114 ALA A CB 1 ATOM 785 N N . LEU A 1 115 ? 47.318 58.676 24.192 1.00 8.97 ? 115 LEU A N 1 ATOM 786 C CA . LEU A 1 115 ? 48.540 58.020 24.583 1.00 9.93 ? 115 LEU A CA 1 ATOM 787 C C . LEU A 1 115 ? 48.544 57.753 26.086 1.00 10.47 ? 115 LEU A C 1 ATOM 788 O O . LEU A 1 115 ? 48.813 56.637 26.519 1.00 11.73 ? 115 LEU A O 1 ATOM 789 C CB . LEU A 1 115 ? 49.731 58.871 24.165 1.00 9.48 ? 115 LEU A CB 1 ATOM 790 C CG . LEU A 1 115 ? 51.135 58.391 24.544 1.00 11.01 ? 115 LEU A CG 1 ATOM 791 C CD1 . LEU A 1 115 ? 51.345 56.931 24.165 1.00 14.43 ? 115 LEU A CD1 1 ATOM 792 C CD2 . LEU A 1 115 ? 52.199 59.275 23.880 1.00 13.19 ? 115 LEU A CD2 1 ATOM 793 N N . ARG A 1 116 ? 48.159 58.760 26.848 1.00 10.63 ? 116 ARG A N 1 ATOM 794 C CA . ARG A 1 116 ? 48.162 58.634 28.302 1.00 11.36 ? 116 ARG A CA 1 ATOM 795 C C . ARG A 1 116 ? 47.122 57.614 28.766 1.00 10.24 ? 116 ARG A C 1 ATOM 796 O O . ARG A 1 116 ? 47.418 56.715 29.565 1.00 10.97 ? 116 ARG A O 1 ATOM 797 C CB . ARG A 1 116 ? 47.909 59.998 28.925 1.00 12.34 ? 116 ARG A CB 1 ATOM 798 C CG . ARG A 1 116 ? 47.466 59.955 30.380 1.00 17.33 ? 116 ARG A CG 1 ATOM 799 C CD . ARG A 1 116 ? 46.738 61.224 30.796 1.00 24.31 ? 116 ARG A CD 1 ATOM 800 N NE . ARG A 1 116 ? 46.244 61.154 32.172 1.00 28.44 ? 116 ARG A NE 1 ATOM 801 C CZ . ARG A 1 116 ? 45.879 62.212 32.889 1.00 31.77 ? 116 ARG A CZ 1 ATOM 802 N NH1 . ARG A 1 116 ? 45.957 63.432 32.369 1.00 32.87 ? 116 ARG A NH1 1 ATOM 803 N NH2 . ARG A 1 116 ? 45.438 62.046 34.137 1.00 33.78 ? 116 ARG A NH2 1 ATOM 804 N N . HIS A 1 117 ? 45.905 57.732 28.270 1.00 9.95 ? 117 HIS A N 1 ATOM 805 C CA A HIS A 1 117 ? 44.851 56.870 28.772 0.50 9.93 ? 117 HIS A CA 1 ATOM 806 C CA B HIS A 1 117 ? 44.822 56.887 28.740 0.50 10.42 ? 117 HIS A CA 1 ATOM 807 C C . HIS A 1 117 ? 44.985 55.436 28.333 1.00 10.17 ? 117 HIS A C 1 ATOM 808 O O . HIS A 1 117 ? 44.653 54.541 29.101 1.00 9.76 ? 117 HIS A O 1 ATOM 809 C CB A HIS A 1 117 ? 43.464 57.413 28.457 0.50 9.85 ? 117 HIS A CB 1 ATOM 810 C CB B HIS A 1 117 ? 43.480 57.402 28.245 0.50 10.71 ? 117 HIS A CB 1 ATOM 811 C CG A HIS A 1 117 ? 43.127 58.639 29.239 0.50 9.04 ? 117 HIS A CG 1 ATOM 812 C CG B HIS A 1 117 ? 42.338 57.077 29.153 0.50 12.23 ? 117 HIS A CG 1 ATOM 813 N ND1 A HIS A 1 117 ? 42.482 58.596 30.458 0.50 10.32 ? 117 HIS A ND1 1 ATOM 814 N ND1 B HIS A 1 117 ? 42.039 57.826 30.274 0.50 12.31 ? 117 HIS A ND1 1 ATOM 815 C CD2 A HIS A 1 117 ? 43.371 59.945 28.988 0.50 10.10 ? 117 HIS A CD2 1 ATOM 816 C CD2 B HIS A 1 117 ? 41.423 56.079 29.116 0.50 12.67 ? 117 HIS A CD2 1 ATOM 817 C CE1 A HIS A 1 117 ? 42.343 59.824 30.923 0.50 9.42 ? 117 HIS A CE1 1 ATOM 818 C CE1 B HIS A 1 117 ? 40.985 57.307 30.881 0.50 13.68 ? 117 HIS A CE1 1 ATOM 819 N NE2 A HIS A 1 117 ? 42.868 60.664 30.047 0.50 8.92 ? 117 HIS A NE2 1 ATOM 820 N NE2 B HIS A 1 117 ? 40.587 56.254 30.194 0.50 11.48 ? 117 HIS A NE2 1 ATOM 821 N N . LEU A 1 118 ? 45.453 55.179 27.114 1.00 8.92 ? 118 LEU A N 1 ATOM 822 C CA . LEU A 1 118 ? 45.684 53.803 26.678 1.00 9.47 ? 118 LEU A CA 1 ATOM 823 C C . LEU A 1 118 ? 46.847 53.182 27.450 1.00 9.61 ? 118 LEU A C 1 ATOM 824 O O . LEU A 1 118 ? 46.775 52.016 27.900 1.00 11.16 ? 118 LEU A O 1 ATOM 825 C CB . LEU A 1 118 ? 45.954 53.729 25.153 1.00 9.05 ? 118 LEU A CB 1 ATOM 826 C CG . LEU A 1 118 ? 44.715 54.144 24.321 1.00 11.07 ? 118 LEU A CG 1 ATOM 827 C CD1 . LEU A 1 118 ? 45.103 54.444 22.840 1.00 12.32 ? 118 LEU A CD1 1 ATOM 828 C CD2 . LEU A 1 118 ? 43.604 53.169 24.418 1.00 11.83 ? 118 LEU A CD2 1 ATOM 829 N N . HIS A 1 119 ? 47.910 53.939 27.637 1.00 10.65 ? 119 HIS A N 1 ATOM 830 C CA . HIS A 1 119 ? 49.044 53.455 28.409 1.00 11.46 ? 119 HIS A CA 1 ATOM 831 C C . HIS A 1 119 ? 48.561 53.031 29.804 1.00 12.53 ? 119 HIS A C 1 ATOM 832 O O . HIS A 1 119 ? 48.903 51.982 30.275 1.00 13.64 ? 119 HIS A O 1 ATOM 833 C CB . HIS A 1 119 ? 50.093 54.562 28.504 1.00 13.42 ? 119 HIS A CB 1 ATOM 834 C CG . HIS A 1 119 ? 51.231 54.266 29.426 1.00 17.87 ? 119 HIS A CG 1 ATOM 835 N ND1 . HIS A 1 119 ? 52.272 53.434 29.083 1.00 23.46 ? 119 HIS A ND1 1 ATOM 836 C CD2 . HIS A 1 119 ? 51.522 54.740 30.661 1.00 20.91 ? 119 HIS A CD2 1 ATOM 837 C CE1 . HIS A 1 119 ? 53.134 53.377 30.081 1.00 23.29 ? 119 HIS A CE1 1 ATOM 838 N NE2 . HIS A 1 119 ? 52.709 54.165 31.045 1.00 22.41 ? 119 HIS A NE2 1 ATOM 839 N N . ASP A 1 120 ? 47.735 53.854 30.424 1.00 12.53 ? 120 ASP A N 1 ATOM 840 C CA . ASP A 1 120 ? 47.305 53.605 31.814 1.00 13.76 ? 120 ASP A CA 1 ATOM 841 C C . ASP A 1 120 ? 46.208 52.545 31.964 1.00 13.92 ? 120 ASP A C 1 ATOM 842 O O . ASP A 1 120 ? 45.975 52.045 33.069 1.00 14.76 ? 120 ASP A O 1 ATOM 843 C CB . ASP A 1 120 ? 46.846 54.918 32.461 1.00 14.47 ? 120 ASP A CB 1 ATOM 844 C CG . ASP A 1 120 ? 48.002 55.838 32.789 1.00 17.34 ? 120 ASP A CG 1 ATOM 845 O OD1 . ASP A 1 120 ? 49.174 55.396 32.729 1.00 21.82 ? 120 ASP A OD1 1 ATOM 846 O OD2 . ASP A 1 120 ? 47.828 57.028 33.111 1.00 21.76 ? 120 ASP A OD2 1 ATOM 847 N N . ASN A 1 121 ? 45.507 52.211 30.888 1.00 12.60 ? 121 ASN A N 1 ATOM 848 C CA . ASN A 1 121 ? 44.331 51.339 30.937 1.00 12.01 ? 121 ASN A CA 1 ATOM 849 C C . ASN A 1 121 ? 44.453 50.258 29.897 1.00 12.86 ? 121 ASN A C 1 ATOM 850 O O . ASN A 1 121 ? 43.971 50.420 28.773 1.00 11.96 ? 121 ASN A O 1 ATOM 851 C CB . ASN A 1 121 ? 43.029 52.115 30.728 1.00 11.53 ? 121 ASN A CB 1 ATOM 852 C CG . ASN A 1 121 ? 42.790 53.131 31.832 1.00 12.44 ? 121 ASN A CG 1 ATOM 853 O OD1 . ASN A 1 121 ? 42.249 52.790 32.922 1.00 13.89 ? 121 ASN A OD1 1 ATOM 854 N ND2 . ASN A 1 121 ? 43.210 54.350 31.598 1.00 11.95 ? 121 ASN A ND2 1 ATOM 855 N N . PRO A 1 122 ? 45.130 49.176 30.234 1.00 12.49 ? 122 PRO A N 1 ATOM 856 C CA . PRO A 1 122 ? 45.498 48.179 29.232 1.00 13.05 ? 122 PRO A CA 1 ATOM 857 C C . PRO A 1 122 ? 44.375 47.520 28.451 1.00 12.65 ? 122 PRO A C 1 ATOM 858 O O . PRO A 1 122 ? 44.664 47.010 27.350 1.00 13.36 ? 122 PRO A O 1 ATOM 859 C CB . PRO A 1 122 ? 46.289 47.139 30.045 1.00 14.13 ? 122 PRO A CB 1 ATOM 860 C CG . PRO A 1 122 ? 46.815 47.934 31.209 1.00 14.79 ? 122 PRO A CG 1 ATOM 861 C CD . PRO A 1 122 ? 45.665 48.834 31.583 1.00 13.79 ? 122 PRO A CD 1 ATOM 862 N N . GLU A 1 123 ? 43.143 47.521 28.952 1.00 11.57 ? 123 GLU A N 1 ATOM 863 C CA . GLU A 1 123 ? 42.026 46.946 28.172 1.00 12.64 ? 123 GLU A CA 1 ATOM 864 C C . GLU A 1 123 ? 41.322 47.942 27.254 1.00 11.74 ? 123 GLU A C 1 ATOM 865 O O . GLU A 1 123 ? 40.492 47.536 26.447 1.00 11.99 ? 123 GLU A O 1 ATOM 866 C CB . GLU A 1 123 ? 40.977 46.265 29.061 1.00 14.80 ? 123 GLU A CB 1 ATOM 867 C CG . GLU A 1 123 ? 41.521 45.069 29.853 1.00 20.00 ? 123 GLU A CG 1 ATOM 868 C CD . GLU A 1 123 ? 42.007 43.936 28.959 1.00 26.88 ? 123 GLU A CD 1 ATOM 869 O OE1 . GLU A 1 123 ? 41.173 43.309 28.257 1.00 31.03 ? 123 GLU A OE1 1 ATOM 870 O OE2 . GLU A 1 123 ? 43.233 43.660 28.951 1.00 32.23 ? 123 GLU A OE2 1 ATOM 871 N N . MET A 1 124 ? 41.634 49.223 27.400 1.00 10.60 ? 124 MET A N 1 ATOM 872 C CA . MET A 1 124 ? 41.021 50.241 26.545 1.00 9.28 ? 124 MET A CA 1 ATOM 873 C C . MET A 1 124 ? 41.664 50.140 25.154 1.00 9.68 ? 124 MET A C 1 ATOM 874 O O . MET A 1 124 ? 42.823 49.805 25.032 1.00 9.51 ? 124 MET A O 1 ATOM 875 C CB . MET A 1 124 ? 41.229 51.627 27.175 1.00 11.32 ? 124 MET A CB 1 ATOM 876 C CG . MET A 1 124 ? 40.552 52.791 26.446 1.00 11.53 ? 124 MET A CG 1 ATOM 877 S SD . MET A 1 124 ? 38.791 52.477 26.293 1.00 13.63 ? 124 MET A SD 1 ATOM 878 C CE . MET A 1 124 ? 38.245 53.991 25.443 1.00 15.51 ? 124 MET A CE 1 ATOM 879 N N . LYS A 1 125 ? 40.877 50.490 24.131 1.00 8.67 ? 125 LYS A N 1 ATOM 880 C CA . LYS A 1 125 ? 41.285 50.402 22.718 1.00 8.20 ? 125 LYS A CA 1 ATOM 881 C C . LYS A 1 125 ? 40.892 51.698 22.026 1.00 8.06 ? 125 LYS A C 1 ATOM 882 O O . LYS A 1 125 ? 40.070 52.489 22.524 1.00 8.66 ? 125 LYS A O 1 ATOM 883 C CB . LYS A 1 125 ? 40.587 49.226 22.025 1.00 9.69 ? 125 LYS A CB 1 ATOM 884 C CG . LYS A 1 125 ? 40.877 47.873 22.660 1.00 12.51 ? 125 LYS A CG 1 ATOM 885 C CD . LYS A 1 125 ? 42.175 47.317 22.173 1.00 15.35 ? 125 LYS A CD 1 ATOM 886 C CE . LYS A 1 125 ? 42.732 46.285 23.133 1.00 23.37 ? 125 LYS A CE 1 ATOM 887 N NZ . LYS A 1 125 ? 41.915 45.074 23.119 1.00 22.98 ? 125 LYS A NZ 1 ATOM 888 N N . PHE A 1 126 ? 41.485 51.926 20.845 1.00 7.75 ? 126 PHE A N 1 ATOM 889 C CA . PHE A 1 126 ? 41.196 53.162 20.073 1.00 6.87 ? 126 PHE A CA 1 ATOM 890 C C . PHE A 1 126 ? 41.695 52.900 18.657 1.00 6.16 ? 126 PHE A C 1 ATOM 891 O O . PHE A 1 126 ? 42.754 52.305 18.457 1.00 7.61 ? 126 PHE A O 1 ATOM 892 C CB . PHE A 1 126 ? 41.976 54.335 20.668 1.00 8.17 ? 126 PHE A CB 1 ATOM 893 C CG . PHE A 1 126 ? 41.589 55.720 20.217 1.00 7.16 ? 126 PHE A CG 1 ATOM 894 C CD1 . PHE A 1 126 ? 40.283 56.169 20.241 1.00 8.66 ? 126 PHE A CD1 1 ATOM 895 C CD2 . PHE A 1 126 ? 42.594 56.634 19.872 1.00 8.91 ? 126 PHE A CD2 1 ATOM 896 C CE1 . PHE A 1 126 ? 39.976 57.505 19.875 1.00 7.70 ? 126 PHE A CE1 1 ATOM 897 C CE2 . PHE A 1 126 ? 42.321 57.941 19.533 1.00 8.08 ? 126 PHE A CE2 1 ATOM 898 C CZ . PHE A 1 126 ? 41.013 58.386 19.513 1.00 7.64 ? 126 PHE A CZ 1 ATOM 899 N N . ILE A 1 127 ? 40.917 53.352 17.678 1.00 6.06 ? 127 ILE A N 1 ATOM 900 C CA . ILE A 1 127 ? 41.358 53.250 16.279 1.00 6.13 ? 127 ILE A CA 1 ATOM 901 C C . ILE A 1 127 ? 41.623 54.647 15.741 1.00 6.58 ? 127 ILE A C 1 ATOM 902 O O . ILE A 1 127 ? 41.001 55.637 16.191 1.00 6.11 ? 127 ILE A O 1 ATOM 903 C CB . ILE A 1 127 ? 40.371 52.517 15.382 1.00 6.52 ? 127 ILE A CB 1 ATOM 904 C CG1 . ILE A 1 127 ? 38.964 53.104 15.392 1.00 6.96 ? 127 ILE A CG1 1 ATOM 905 C CG2 . ILE A 1 127 ? 40.317 51.023 15.800 1.00 7.99 ? 127 ILE A CG2 1 ATOM 906 C CD1 . ILE A 1 127 ? 38.060 52.545 14.282 1.00 7.06 ? 127 ILE A CD1 1 ATOM 907 N N . TRP A 1 128 ? 42.574 54.705 14.808 1.00 6.80 ? 128 TRP A N 1 ATOM 908 C CA . TRP A 1 128 ? 42.948 55.977 14.207 1.00 5.93 ? 128 TRP A CA 1 ATOM 909 C C . TRP A 1 128 ? 43.045 55.838 12.703 1.00 5.47 ? 128 TRP A C 1 ATOM 910 O O . TRP A 1 128 ? 43.705 54.916 12.228 1.00 6.01 ? 128 TRP A O 1 ATOM 911 C CB . TRP A 1 128 ? 44.288 56.461 14.769 1.00 6.24 ? 128 TRP A CB 1 ATOM 912 C CG . TRP A 1 128 ? 44.513 57.893 14.407 1.00 7.02 ? 128 TRP A CG 1 ATOM 913 C CD1 . TRP A 1 128 ? 45.229 58.388 13.329 1.00 6.46 ? 128 TRP A CD1 1 ATOM 914 C CD2 . TRP A 1 128 ? 43.947 59.011 15.064 1.00 6.27 ? 128 TRP A CD2 1 ATOM 915 N NE1 . TRP A 1 128 ? 45.164 59.764 13.317 1.00 5.65 ? 128 TRP A NE1 1 ATOM 916 C CE2 . TRP A 1 128 ? 44.369 60.178 14.368 1.00 6.17 ? 128 TRP A CE2 1 ATOM 917 C CE3 . TRP A 1 128 ? 43.114 59.153 16.195 1.00 6.56 ? 128 TRP A CE3 1 ATOM 918 C CZ2 . TRP A 1 128 ? 43.968 61.479 14.765 1.00 6.93 ? 128 TRP A CZ2 1 ATOM 919 C CZ3 . TRP A 1 128 ? 42.728 60.404 16.575 1.00 6.50 ? 128 TRP A CZ3 1 ATOM 920 C CH2 . TRP A 1 128 ? 43.171 61.572 15.869 1.00 7.65 ? 128 TRP A CH2 1 ATOM 921 N N . ALA A 1 129 ? 42.481 56.797 11.967 1.00 6.64 ? 129 ALA A N 1 ATOM 922 C CA . ALA A 1 129 ? 42.457 56.736 10.503 1.00 7.87 ? 129 ALA A CA 1 ATOM 923 C C . ALA A 1 129 ? 43.409 57.702 9.772 1.00 9.38 ? 129 ALA A C 1 ATOM 924 O O . ALA A 1 129 ? 43.976 57.329 8.737 1.00 10.63 ? 129 ALA A O 1 ATOM 925 C CB . ALA A 1 129 ? 41.036 57.010 9.995 1.00 9.01 ? 129 ALA A CB 1 ATOM 926 N N . GLU A 1 130 ? 43.493 58.948 10.234 1.00 9.19 ? 130 GLU A N 1 ATOM 927 C CA . GLU A 1 130 ? 44.086 60.064 9.442 1.00 7.83 ? 130 GLU A CA 1 ATOM 928 C C . GLU A 1 130 ? 45.578 60.224 9.743 1.00 6.58 ? 130 GLU A C 1 ATOM 929 O O . GLU A 1 130 ? 45.968 60.805 10.763 1.00 6.17 ? 130 GLU A O 1 ATOM 930 C CB . GLU A 1 130 ? 43.348 61.383 9.719 1.00 9.74 ? 130 GLU A CB 1 ATOM 931 C CG . GLU A 1 130 ? 41.839 61.323 9.397 1.00 10.84 ? 130 GLU A CG 1 ATOM 932 C CD . GLU A 1 130 ? 40.956 60.906 10.577 1.00 15.95 ? 130 GLU A CD 1 ATOM 933 O OE1 . GLU A 1 130 ? 41.501 60.596 11.682 1.00 15.86 ? 130 GLU A OE1 1 ATOM 934 O OE2 . GLU A 1 130 ? 39.699 60.880 10.421 1.00 15.99 ? 130 GLU A OE2 1 ATOM 935 N N . ILE A 1 131 ? 46.442 59.720 8.863 1.00 5.29 ? 131 ILE A N 1 ATOM 936 C CA . ILE A 1 131 ? 47.855 59.692 9.183 1.00 5.90 ? 131 ILE A CA 1 ATOM 937 C C . ILE A 1 131 ? 48.482 61.052 9.042 1.00 6.75 ? 131 ILE A C 1 ATOM 938 O O . ILE A 1 131 ? 49.492 61.335 9.707 1.00 7.82 ? 131 ILE A O 1 ATOM 939 C CB . ILE A 1 131 ? 48.576 58.594 8.359 1.00 7.09 ? 131 ILE A CB 1 ATOM 940 C CG1 . ILE A 1 131 ? 47.959 57.217 8.653 1.00 7.25 ? 131 ILE A CG1 1 ATOM 941 C CG2 . ILE A 1 131 ? 50.046 58.585 8.650 1.00 8.34 ? 131 ILE A CG2 1 ATOM 942 C CD1 . ILE A 1 131 ? 47.847 56.900 10.211 1.00 10.50 ? 131 ILE A CD1 1 ATOM 943 N N . SER A 1 132 ? 47.914 61.930 8.235 1.00 5.05 ? 132 SER A N 1 ATOM 944 C CA . SER A 1 132 ? 48.403 63.317 8.212 1.00 5.83 ? 132 SER A CA 1 ATOM 945 C C . SER A 1 132 ? 48.489 63.908 9.625 1.00 5.91 ? 132 SER A C 1 ATOM 946 O O . SER A 1 132 ? 49.537 64.470 10.007 1.00 6.54 ? 132 SER A O 1 ATOM 947 C CB . SER A 1 132 ? 47.507 64.173 7.350 1.00 6.23 ? 132 SER A CB 1 ATOM 948 O OG . SER A 1 132 ? 46.146 64.086 7.735 1.00 6.24 ? 132 SER A OG 1 ATOM 949 N N . TYR A 1 133 ? 47.439 63.744 10.411 1.00 5.71 ? 133 TYR A N 1 ATOM 950 C CA . TYR A 1 133 ? 47.469 64.244 11.773 1.00 5.90 ? 133 TYR A CA 1 ATOM 951 C C . TYR A 1 133 ? 48.424 63.447 12.634 1.00 6.08 ? 133 TYR A C 1 ATOM 952 O O . TYR A 1 133 ? 49.098 64.032 13.517 1.00 7.10 ? 133 TYR A O 1 ATOM 953 C CB . TYR A 1 133 ? 46.093 64.185 12.415 1.00 5.61 ? 133 TYR A CB 1 ATOM 954 C CG . TYR A 1 133 ? 45.162 65.310 12.071 1.00 5.25 ? 133 TYR A CG 1 ATOM 955 C CD1 . TYR A 1 133 ? 45.498 66.624 12.353 1.00 6.89 ? 133 TYR A CD1 1 ATOM 956 C CD2 . TYR A 1 133 ? 43.901 65.053 11.532 1.00 5.94 ? 133 TYR A CD2 1 ATOM 957 C CE1 . TYR A 1 133 ? 44.627 67.667 12.038 1.00 5.53 ? 133 TYR A CE1 1 ATOM 958 C CE2 . TYR A 1 133 ? 43.004 66.096 11.250 1.00 6.28 ? 133 TYR A CE2 1 ATOM 959 C CZ . TYR A 1 133 ? 43.393 67.395 11.519 1.00 6.84 ? 133 TYR A CZ 1 ATOM 960 O OH . TYR A 1 133 ? 42.564 68.458 11.219 1.00 7.65 ? 133 TYR A OH 1 ATOM 961 N N . PHE A 1 134 ? 48.446 62.128 12.455 1.00 5.57 ? 134 PHE A N 1 ATOM 962 C CA . PHE A 1 134 ? 49.277 61.326 13.353 1.00 6.71 ? 134 PHE A CA 1 ATOM 963 C C . PHE A 1 134 ? 50.739 61.660 13.135 1.00 7.47 ? 134 PHE A C 1 ATOM 964 O O . PHE A 1 134 ? 51.513 61.762 14.104 1.00 7.68 ? 134 PHE A O 1 ATOM 965 C CB . PHE A 1 134 ? 48.998 59.837 13.183 1.00 6.41 ? 134 PHE A CB 1 ATOM 966 C CG . PHE A 1 134 ? 49.568 59.022 14.299 1.00 7.22 ? 134 PHE A CG 1 ATOM 967 C CD1 . PHE A 1 134 ? 48.833 58.802 15.468 1.00 8.90 ? 134 PHE A CD1 1 ATOM 968 C CD2 . PHE A 1 134 ? 50.849 58.498 14.181 1.00 10.59 ? 134 PHE A CD2 1 ATOM 969 C CE1 . PHE A 1 134 ? 49.401 58.047 16.515 1.00 10.45 ? 134 PHE A CE1 1 ATOM 970 C CE2 . PHE A 1 134 ? 51.427 57.735 15.243 1.00 7.72 ? 134 PHE A CE2 1 ATOM 971 C CZ . PHE A 1 134 ? 50.673 57.507 16.390 1.00 9.61 ? 134 PHE A CZ 1 ATOM 972 N N . ALA A 1 135 ? 51.146 61.821 11.876 1.00 7.19 ? 135 ALA A N 1 ATOM 973 C CA . ALA A 1 135 ? 52.531 62.185 11.547 1.00 7.73 ? 135 ALA A CA 1 ATOM 974 C C . ALA A 1 135 ? 52.865 63.567 12.092 1.00 8.35 ? 135 ALA A C 1 ATOM 975 O O . ALA A 1 135 ? 53.985 63.752 12.636 1.00 11.38 ? 135 ALA A O 1 ATOM 976 C CB . ALA A 1 135 ? 52.767 62.110 10.036 1.00 9.22 ? 135 ALA A CB 1 ATOM 977 N N . ARG A 1 136 ? 51.920 64.503 12.008 1.00 8.68 ? 136 ARG A N 1 ATOM 978 C CA . ARG A 1 136 ? 52.087 65.878 12.541 1.00 9.43 ? 136 ARG A CA 1 ATOM 979 C C . ARG A 1 136 ? 52.310 65.803 14.061 1.00 10.57 ? 136 ARG A C 1 ATOM 980 O O . ARG A 1 136 ? 53.143 66.542 14.609 1.00 12.48 ? 136 ARG A O 1 ATOM 981 C CB . ARG A 1 136 ? 50.846 66.720 12.244 1.00 9.66 ? 136 ARG A CB 1 ATOM 982 C CG . ARG A 1 136 ? 50.839 68.134 12.831 1.00 12.07 ? 136 ARG A CG 1 ATOM 983 C CD . ARG A 1 136 ? 51.761 69.104 12.109 1.00 14.20 ? 136 ARG A CD 1 ATOM 984 N NE . ARG A 1 136 ? 51.694 70.403 12.785 1.00 13.89 ? 136 ARG A NE 1 ATOM 985 C CZ . ARG A 1 136 ? 52.416 70.724 13.850 1.00 14.66 ? 136 ARG A CZ 1 ATOM 986 N NH1 . ARG A 1 136 ? 53.284 69.851 14.360 1.00 15.57 ? 136 ARG A NH1 1 ATOM 987 N NH2 . ARG A 1 136 ? 52.260 71.936 14.412 1.00 13.62 ? 136 ARG A NH2 1 ATOM 988 N N . PHE A 1 137 ? 51.627 64.884 14.748 1.00 8.86 ? 137 PHE A N 1 ATOM 989 C CA . PHE A 1 137 ? 51.757 64.734 16.189 1.00 9.41 ? 137 PHE A CA 1 ATOM 990 C C . PHE A 1 137 ? 53.035 64.025 16.581 1.00 10.58 ? 137 PHE A C 1 ATOM 991 O O . PHE A 1 137 ? 53.800 64.515 17.432 1.00 10.57 ? 137 PHE A O 1 ATOM 992 C CB . PHE A 1 137 ? 50.563 63.922 16.676 1.00 8.46 ? 137 PHE A CB 1 ATOM 993 C CG . PHE A 1 137 ? 50.582 63.654 18.140 1.00 9.06 ? 137 PHE A CG 1 ATOM 994 C CD1 . PHE A 1 137 ? 50.309 64.689 19.008 1.00 9.92 ? 137 PHE A CD1 1 ATOM 995 C CD2 . PHE A 1 137 ? 50.849 62.394 18.614 1.00 10.16 ? 137 PHE A CD2 1 ATOM 996 C CE1 . PHE A 1 137 ? 50.287 64.485 20.359 1.00 12.57 ? 137 PHE A CE1 1 ATOM 997 C CE2 . PHE A 1 137 ? 50.868 62.167 20.013 1.00 10.78 ? 137 PHE A CE2 1 ATOM 998 C CZ . PHE A 1 137 ? 50.568 63.227 20.852 1.00 9.23 ? 137 PHE A CZ 1 ATOM 999 N N . TYR A 1 138 ? 53.304 62.904 15.935 1.00 10.59 ? 138 TYR A N 1 ATOM 1000 C CA A TYR A 1 138 ? 54.404 62.034 16.316 0.50 12.06 ? 138 TYR A CA 1 ATOM 1001 C CA B TYR A 1 138 ? 54.395 62.018 16.349 0.50 12.80 ? 138 TYR A CA 1 ATOM 1002 C C . TYR A 1 138 ? 55.729 62.755 16.203 1.00 13.93 ? 138 TYR A C 1 ATOM 1003 O O . TYR A 1 138 ? 56.622 62.601 17.036 1.00 13.78 ? 138 TYR A O 1 ATOM 1004 C CB A TYR A 1 138 ? 54.430 60.812 15.416 0.50 10.53 ? 138 TYR A CB 1 ATOM 1005 C CB B TYR A 1 138 ? 54.544 60.856 15.365 0.50 12.62 ? 138 TYR A CB 1 ATOM 1006 C CG A TYR A 1 138 ? 55.421 59.749 15.816 0.50 9.24 ? 138 TYR A CG 1 ATOM 1007 C CG B TYR A 1 138 ? 55.771 60.006 15.603 0.50 12.43 ? 138 TYR A CG 1 ATOM 1008 C CD1 A TYR A 1 138 ? 55.092 58.818 16.777 0.50 6.75 ? 138 TYR A CD1 1 ATOM 1009 C CD1 B TYR A 1 138 ? 56.979 60.309 14.989 0.50 12.85 ? 138 TYR A CD1 1 ATOM 1010 C CD2 A TYR A 1 138 ? 56.645 59.660 15.213 0.50 8.35 ? 138 TYR A CD2 1 ATOM 1011 C CD2 B TYR A 1 138 ? 55.722 58.901 16.442 0.50 13.84 ? 138 TYR A CD2 1 ATOM 1012 C CE1 A TYR A 1 138 ? 55.967 57.827 17.140 0.50 6.96 ? 138 TYR A CE1 1 ATOM 1013 C CE1 B TYR A 1 138 ? 58.104 59.535 15.203 0.50 13.97 ? 138 TYR A CE1 1 ATOM 1014 C CE2 A TYR A 1 138 ? 57.550 58.651 15.574 0.50 6.06 ? 138 TYR A CE2 1 ATOM 1015 C CE2 B TYR A 1 138 ? 56.841 58.121 16.663 0.50 15.14 ? 138 TYR A CE2 1 ATOM 1016 C CZ A TYR A 1 138 ? 57.190 57.748 16.534 0.50 8.23 ? 138 TYR A CZ 1 ATOM 1017 C CZ B TYR A 1 138 ? 58.029 58.442 16.041 0.50 14.28 ? 138 TYR A CZ 1 ATOM 1018 O OH A TYR A 1 138 ? 58.045 56.731 16.922 0.50 9.18 ? 138 TYR A OH 1 ATOM 1019 O OH B TYR A 1 138 ? 59.146 57.669 16.258 0.50 15.90 ? 138 TYR A OH 1 ATOM 1020 N N A HIS A 1 139 ? 55.866 63.539 15.152 0.50 14.42 ? 139 HIS A N 1 ATOM 1021 N N B HIS A 1 139 ? 55.858 63.546 15.173 0.50 14.92 ? 139 HIS A N 1 ATOM 1022 C CA A HIS A 1 139 ? 57.156 64.178 14.873 0.50 15.98 ? 139 HIS A CA 1 ATOM 1023 C CA B HIS A 1 139 ? 57.133 64.151 14.883 0.50 16.67 ? 139 HIS A CA 1 ATOM 1024 C C A HIS A 1 139 ? 57.424 65.367 15.815 0.50 16.85 ? 139 HIS A C 1 ATOM 1025 C C B HIS A 1 139 ? 57.455 65.185 15.962 0.50 16.95 ? 139 HIS A C 1 ATOM 1026 O O A HIS A 1 139 ? 58.510 65.978 15.804 0.50 16.94 ? 139 HIS A O 1 ATOM 1027 O O B HIS A 1 139 ? 58.611 65.517 16.176 0.50 16.63 ? 139 HIS A O 1 ATOM 1028 C CB A HIS A 1 139 ? 57.234 64.606 13.407 0.50 15.75 ? 139 HIS A CB 1 ATOM 1029 C CB B HIS A 1 139 ? 57.090 64.798 13.494 0.50 17.26 ? 139 HIS A CB 1 ATOM 1030 C CG A HIS A 1 139 ? 57.464 63.477 12.453 0.50 15.82 ? 139 HIS A CG 1 ATOM 1031 C CG B HIS A 1 139 ? 58.422 65.236 12.983 0.50 18.89 ? 139 HIS A CG 1 ATOM 1032 N ND1 A HIS A 1 139 ? 58.641 62.760 12.417 0.50 17.74 ? 139 HIS A ND1 1 ATOM 1033 N ND1 B HIS A 1 139 ? 58.800 66.561 12.910 0.50 19.71 ? 139 HIS A ND1 1 ATOM 1034 C CD2 A HIS A 1 139 ? 56.677 62.962 11.481 0.50 14.65 ? 139 HIS A CD2 1 ATOM 1035 C CD2 B HIS A 1 139 ? 59.464 64.519 12.511 0.50 20.68 ? 139 HIS A CD2 1 ATOM 1036 C CE1 A HIS A 1 139 ? 58.564 61.842 11.469 0.50 17.87 ? 139 HIS A CE1 1 ATOM 1037 C CE1 B HIS A 1 139 ? 60.023 66.637 12.421 0.50 21.79 ? 139 HIS A CE1 1 ATOM 1038 N NE2 A HIS A 1 139 ? 57.390 61.956 10.872 0.50 14.90 ? 139 HIS A NE2 1 ATOM 1039 N NE2 B HIS A 1 139 ? 60.445 65.414 12.161 0.50 21.11 ? 139 HIS A NE2 1 ATOM 1040 N N . ASP A 1 140 ? 56.439 65.691 16.643 1.00 16.68 ? 140 ASP A N 1 ATOM 1041 C CA . ASP A 1 140 ? 56.618 66.660 17.729 1.00 17.65 ? 140 ASP A CA 1 ATOM 1042 C C . ASP A 1 140 ? 56.810 66.024 19.113 1.00 16.69 ? 140 ASP A C 1 ATOM 1043 O O . ASP A 1 140 ? 57.075 66.736 20.108 1.00 17.32 ? 140 ASP A O 1 ATOM 1044 C CB . ASP A 1 140 ? 55.437 67.596 17.792 1.00 18.03 ? 140 ASP A CB 1 ATOM 1045 C CG . ASP A 1 140 ? 55.561 68.754 16.829 1.00 21.71 ? 140 ASP A CG 1 ATOM 1046 O OD1 . ASP A 1 140 ? 56.463 68.703 15.958 1.00 26.50 ? 140 ASP A OD1 1 ATOM 1047 O OD2 . ASP A 1 140 ? 54.805 69.746 16.890 1.00 22.58 ? 140 ASP A OD2 1 ATOM 1048 N N . LEU A 1 141 ? 56.674 64.713 19.195 1.00 15.90 ? 141 LEU A N 1 ATOM 1049 C CA . LEU A 1 141 ? 56.873 63.997 20.453 1.00 15.04 ? 141 LEU A CA 1 ATOM 1050 C C . LEU A 1 141 ? 58.322 63.822 20.806 1.00 15.69 ? 141 LEU A C 1 ATOM 1051 O O . LEU A 1 141 ? 59.141 63.581 19.941 1.00 15.67 ? 141 LEU A O 1 ATOM 1052 C CB . LEU A 1 141 ? 56.293 62.587 20.362 1.00 14.52 ? 141 LEU A CB 1 ATOM 1053 C CG . LEU A 1 141 ? 54.781 62.469 20.349 1.00 15.37 ? 141 LEU A CG 1 ATOM 1054 C CD1 . LEU A 1 141 ? 54.409 60.984 20.295 1.00 13.77 ? 141 LEU A CD1 1 ATOM 1055 C CD2 . LEU A 1 141 ? 54.184 63.156 21.581 1.00 14.88 ? 141 LEU A CD2 1 ATOM 1056 N N . GLY A 1 142 ? 58.621 63.927 22.099 1.00 16.66 ? 142 GLY A N 1 ATOM 1057 C CA . GLY A 1 142 ? 59.907 63.515 22.616 1.00 17.64 ? 142 GLY A CA 1 ATOM 1058 C C . GLY A 1 142 ? 60.081 62.010 22.490 1.00 18.58 ? 142 GLY A C 1 ATOM 1059 O O . GLY A 1 142 ? 59.083 61.254 22.355 1.00 17.97 ? 142 GLY A O 1 ATOM 1060 N N . GLU A 1 143 ? 61.330 61.563 22.549 1.00 18.87 ? 143 GLU A N 1 ATOM 1061 C CA . GLU A 1 143 ? 61.651 60.150 22.364 1.00 19.70 ? 143 GLU A CA 1 ATOM 1062 C C . GLU A 1 143 ? 60.950 59.234 23.381 1.00 19.40 ? 143 GLU A C 1 ATOM 1063 O O . GLU A 1 143 ? 60.465 58.158 23.021 1.00 18.79 ? 143 GLU A O 1 ATOM 1064 C CB . GLU A 1 143 ? 63.173 59.926 22.331 1.00 20.86 ? 143 GLU A CB 1 ATOM 1065 C CG . GLU A 1 143 ? 63.605 58.594 21.740 1.00 24.30 ? 143 GLU A CG 1 ATOM 1066 C CD . GLU A 1 143 ? 63.383 58.480 20.226 1.00 30.04 ? 143 GLU A CD 1 ATOM 1067 O OE1 . GLU A 1 143 ? 63.087 59.498 19.539 1.00 33.24 ? 143 GLU A OE1 1 ATOM 1068 O OE2 . GLU A 1 143 ? 63.515 57.347 19.711 1.00 34.36 ? 143 GLU A OE2 1 ATOM 1069 N N . ASN A 1 144 ? 60.856 59.668 24.622 1.00 20.30 ? 144 ASN A N 1 ATOM 1070 C CA . ASN A 1 144 ? 60.142 58.916 25.641 1.00 20.08 ? 144 ASN A CA 1 ATOM 1071 C C . ASN A 1 144 ? 58.700 58.586 25.201 1.00 19.11 ? 144 ASN A C 1 ATOM 1072 O O . ASN A 1 144 ? 58.276 57.454 25.242 1.00 18.63 ? 144 ASN A O 1 ATOM 1073 C CB . ASN A 1 144 ? 60.165 59.708 26.954 1.00 21.79 ? 144 ASN A CB 1 ATOM 1074 C CG . ASN A 1 144 ? 59.498 58.985 28.093 1.00 26.15 ? 144 ASN A CG 1 ATOM 1075 O OD1 . ASN A 1 144 ? 60.125 58.189 28.790 1.00 31.81 ? 144 ASN A OD1 1 ATOM 1076 N ND2 . ASN A 1 144 ? 58.218 59.264 28.300 1.00 30.14 ? 144 ASN A ND2 1 ATOM 1077 N N . LYS A 1 145 ? 57.986 59.604 24.753 1.00 17.35 ? 145 LYS A N 1 ATOM 1078 C CA . LYS A 1 145 ? 56.607 59.452 24.280 1.00 15.97 ? 145 LYS A CA 1 ATOM 1079 C C . LYS A 1 145 ? 56.482 58.682 22.959 1.00 14.69 ? 145 LYS A C 1 ATOM 1080 O O . LYS A 1 145 ? 55.536 57.908 22.817 1.00 14.38 ? 145 LYS A O 1 ATOM 1081 C CB . LYS A 1 145 ? 55.895 60.802 24.194 1.00 16.87 ? 145 LYS A CB 1 ATOM 1082 C CG . LYS A 1 145 ? 55.730 61.501 25.557 1.00 18.25 ? 145 LYS A CG 1 ATOM 1083 C CD . LYS A 1 145 ? 54.696 60.825 26.456 1.00 24.17 ? 145 LYS A CD 1 ATOM 1084 C CE . LYS A 1 145 ? 54.596 61.559 27.797 1.00 24.79 ? 145 LYS A CE 1 ATOM 1085 N NZ . LYS A 1 145 ? 55.712 61.225 28.730 1.00 30.25 ? 145 LYS A NZ 1 ATOM 1086 N N A LYS A 1 146 ? 57.418 58.880 22.026 0.50 14.29 ? 146 LYS A N 1 ATOM 1087 N N B LYS A 1 146 ? 57.404 58.903 22.016 0.50 14.16 ? 146 LYS A N 1 ATOM 1088 C CA A LYS A 1 146 ? 57.464 58.081 20.798 0.50 14.29 ? 146 LYS A CA 1 ATOM 1089 C CA B LYS A 1 146 ? 57.462 58.090 20.800 0.50 14.09 ? 146 LYS A CA 1 ATOM 1090 C C A LYS A 1 146 ? 57.558 56.597 21.104 0.50 14.35 ? 146 LYS A C 1 ATOM 1091 C C B LYS A 1 146 ? 57.477 56.615 21.186 0.50 14.05 ? 146 LYS A C 1 ATOM 1092 O O A LYS A 1 146 ? 56.901 55.781 20.456 0.50 14.34 ? 146 LYS A O 1 ATOM 1093 O O B LYS A 1 146 ? 56.659 55.830 20.704 0.50 13.51 ? 146 LYS A O 1 ATOM 1094 C CB A LYS A 1 146 ? 58.643 58.474 19.921 0.50 13.99 ? 146 LYS A CB 1 ATOM 1095 C CB B LYS A 1 146 ? 58.686 58.428 19.945 0.50 13.80 ? 146 LYS A CB 1 ATOM 1096 C CG A LYS A 1 146 ? 58.523 59.811 19.243 0.50 13.97 ? 146 LYS A CG 1 ATOM 1097 C CG B LYS A 1 146 ? 58.613 59.748 19.181 0.50 13.73 ? 146 LYS A CG 1 ATOM 1098 C CD A LYS A 1 146 ? 59.661 59.952 18.266 0.50 14.35 ? 146 LYS A CD 1 ATOM 1099 C CD B LYS A 1 146 ? 59.804 59.885 18.236 0.50 14.20 ? 146 LYS A CD 1 ATOM 1100 C CE A LYS A 1 146 ? 59.651 61.279 17.542 0.50 15.10 ? 146 LYS A CE 1 ATOM 1101 C CE B LYS A 1 146 ? 59.609 60.966 17.156 0.50 14.39 ? 146 LYS A CE 1 ATOM 1102 N NZ A LYS A 1 146 ? 60.862 61.395 16.687 0.50 16.78 ? 146 LYS A NZ 1 ATOM 1103 N NZ B LYS A 1 146 ? 59.747 62.361 17.650 0.50 16.24 ? 146 LYS A NZ 1 ATOM 1104 N N . LEU A 1 147 ? 58.385 56.247 22.091 1.00 14.33 ? 147 LEU A N 1 ATOM 1105 C CA . LEU A 1 147 ? 58.507 54.866 22.547 1.00 14.91 ? 147 LEU A CA 1 ATOM 1106 C C . LEU A 1 147 ? 57.210 54.356 23.206 1.00 13.82 ? 147 LEU A C 1 ATOM 1107 O O . LEU A 1 147 ? 56.770 53.244 22.888 1.00 14.46 ? 147 LEU A O 1 ATOM 1108 C CB . LEU A 1 147 ? 59.725 54.703 23.492 1.00 15.43 ? 147 LEU A CB 1 ATOM 1109 C CG . LEU A 1 147 ? 61.080 54.818 22.793 1.00 18.68 ? 147 LEU A CG 1 ATOM 1110 C CD1 . LEU A 1 147 ? 62.210 54.923 23.791 1.00 20.19 ? 147 LEU A CD1 1 ATOM 1111 C CD2 . LEU A 1 147 ? 61.302 53.618 21.905 1.00 20.26 ? 147 LEU A CD2 1 ATOM 1112 N N . GLN A 1 148 ? 56.595 55.153 24.085 1.00 14.31 ? 148 GLN A N 1 ATOM 1113 C CA . GLN A 1 148 ? 55.290 54.792 24.633 1.00 13.85 ? 148 GLN A CA 1 ATOM 1114 C C . GLN A 1 148 ? 54.243 54.576 23.522 1.00 12.93 ? 148 GLN A C 1 ATOM 1115 O O . GLN A 1 148 ? 53.460 53.650 23.592 1.00 13.11 ? 148 GLN A O 1 ATOM 1116 C CB . GLN A 1 148 ? 54.780 55.870 25.566 1.00 15.00 ? 148 GLN A CB 1 ATOM 1117 C CG . GLN A 1 148 ? 55.509 56.010 26.858 1.00 19.98 ? 148 GLN A CG 1 ATOM 1118 C CD . GLN A 1 148 ? 54.658 56.756 27.865 1.00 26.68 ? 148 GLN A CD 1 ATOM 1119 O OE1 . GLN A 1 148 ? 53.528 57.182 27.544 1.00 29.10 ? 148 GLN A OE1 1 ATOM 1120 N NE2 . GLN A 1 148 ? 55.173 56.908 29.081 1.00 29.52 ? 148 GLN A NE2 1 ATOM 1121 N N . MET A 1 149 ? 54.253 55.451 22.521 1.00 12.05 ? 149 MET A N 1 ATOM 1122 C CA . MET A 1 149 ? 53.298 55.325 21.423 1.00 12.00 ? 149 MET A CA 1 ATOM 1123 C C . MET A 1 149 ? 53.530 54.050 20.630 1.00 12.12 ? 149 MET A C 1 ATOM 1124 O O . MET A 1 149 ? 52.588 53.328 20.336 1.00 11.24 ? 149 MET A O 1 ATOM 1125 C CB . MET A 1 149 ? 53.398 56.549 20.536 1.00 12.80 ? 149 MET A CB 1 ATOM 1126 C CG . MET A 1 149 ? 52.392 56.567 19.407 1.00 12.23 ? 149 MET A CG 1 ATOM 1127 S SD . MET A 1 149 ? 50.695 56.748 19.969 1.00 14.32 ? 149 MET A SD 1 ATOM 1128 C CE . MET A 1 149 ? 50.543 58.580 20.023 1.00 18.20 ? 149 MET A CE 1 ATOM 1129 N N . LYS A 1 150 ? 54.785 53.742 20.323 1.00 11.97 ? 150 LYS A N 1 ATOM 1130 C CA . LYS A 1 150 ? 55.078 52.506 19.617 1.00 13.49 ? 150 LYS A CA 1 ATOM 1131 C C . LYS A 1 150 ? 54.618 51.277 20.394 1.00 12.53 ? 150 LYS A C 1 ATOM 1132 O O . LYS A 1 150 ? 54.131 50.305 19.789 1.00 13.76 ? 150 LYS A O 1 ATOM 1133 C CB . LYS A 1 150 ? 56.559 52.412 19.250 1.00 12.63 ? 150 LYS A CB 1 ATOM 1134 C CG . LYS A 1 150 ? 56.966 53.394 18.153 1.00 14.84 ? 150 LYS A CG 1 ATOM 1135 C CD . LYS A 1 150 ? 58.385 53.159 17.635 1.00 17.96 ? 150 LYS A CD 1 ATOM 1136 C CE . LYS A 1 150 ? 59.361 54.092 18.293 1.00 24.99 ? 150 LYS A CE 1 ATOM 1137 N NZ . LYS A 1 150 ? 60.737 53.918 17.723 1.00 28.25 ? 150 LYS A NZ 1 ATOM 1138 N N A SER A 1 151 ? 54.722 51.321 21.727 0.50 12.10 ? 151 SER A N 1 ATOM 1139 N N B SER A 1 151 ? 54.748 51.322 21.722 0.50 11.96 ? 151 SER A N 1 ATOM 1140 C CA A SER A 1 151 ? 54.339 50.192 22.578 0.50 12.31 ? 151 SER A CA 1 ATOM 1141 C CA B SER A 1 151 ? 54.337 50.206 22.557 0.50 12.05 ? 151 SER A CA 1 ATOM 1142 C C A SER A 1 151 ? 52.821 49.946 22.624 0.50 12.00 ? 151 SER A C 1 ATOM 1143 C C B SER A 1 151 ? 52.837 49.956 22.450 0.50 11.67 ? 151 SER A C 1 ATOM 1144 O O A SER A 1 151 ? 52.363 48.807 22.725 0.50 11.69 ? 151 SER A O 1 ATOM 1145 O O B SER A 1 151 ? 52.411 48.822 22.249 0.50 10.95 ? 151 SER A O 1 ATOM 1146 C CB A SER A 1 151 ? 54.894 50.384 23.993 0.50 13.43 ? 151 SER A CB 1 ATOM 1147 C CB B SER A 1 151 ? 54.736 50.426 24.015 0.50 13.15 ? 151 SER A CB 1 ATOM 1148 O OG A SER A 1 151 ? 54.156 51.365 24.697 0.50 14.90 ? 151 SER A OG 1 ATOM 1149 O OG B SER A 1 151 ? 54.651 49.202 24.723 0.50 14.52 ? 151 SER A OG 1 ATOM 1150 N N . ILE A 1 152 ? 52.026 51.012 22.563 1.00 10.83 ? 152 ILE A N 1 ATOM 1151 C CA . ILE A 1 152 ? 50.573 50.833 22.516 1.00 10.71 ? 152 ILE A CA 1 ATOM 1152 C C . ILE A 1 152 ? 50.062 50.415 21.134 1.00 10.05 ? 152 ILE A C 1 ATOM 1153 O O . ILE A 1 152 ? 48.981 49.862 21.013 1.00 11.28 ? 152 ILE A O 1 ATOM 1154 C CB . ILE A 1 152 ? 49.752 52.009 23.113 1.00 10.83 ? 152 ILE A CB 1 ATOM 1155 C CG1 . ILE A 1 152 ? 50.016 53.322 22.403 1.00 11.77 ? 152 ILE A CG1 1 ATOM 1156 C CG2 . ILE A 1 152 ? 49.993 52.124 24.657 1.00 12.48 ? 152 ILE A CG2 1 ATOM 1157 C CD1 . ILE A 1 152 ? 48.957 54.394 22.734 1.00 12.01 ? 152 ILE A CD1 1 ATOM 1158 N N . VAL A 1 153 ? 50.838 50.689 20.098 1.00 9.90 ? 153 VAL A N 1 ATOM 1159 C CA . VAL A 1 153 ? 50.537 50.158 18.767 1.00 10.73 ? 153 VAL A CA 1 ATOM 1160 C C . VAL A 1 153 ? 50.969 48.693 18.677 1.00 11.51 ? 153 VAL A C 1 ATOM 1161 O O . VAL A 1 153 ? 50.214 47.813 18.216 1.00 12.54 ? 153 VAL A O 1 ATOM 1162 C CB . VAL A 1 153 ? 51.206 51.032 17.714 1.00 11.32 ? 153 VAL A CB 1 ATOM 1163 C CG1 . VAL A 1 153 ? 51.079 50.418 16.320 1.00 12.78 ? 153 VAL A CG1 1 ATOM 1164 C CG2 . VAL A 1 153 ? 50.621 52.431 17.774 1.00 10.57 ? 153 VAL A CG2 1 ATOM 1165 N N . LYS A 1 154 ? 52.183 48.419 19.158 1.00 12.52 ? 154 LYS A N 1 ATOM 1166 C CA . LYS A 1 154 ? 52.694 47.054 19.076 1.00 14.77 ? 154 LYS A CA 1 ATOM 1167 C C . LYS A 1 154 ? 51.814 46.064 19.857 1.00 14.46 ? 154 LYS A C 1 ATOM 1168 O O . LYS A 1 154 ? 51.625 44.908 19.429 1.00 16.13 ? 154 LYS A O 1 ATOM 1169 C CB . LYS A 1 154 ? 54.155 47.001 19.549 1.00 14.79 ? 154 LYS A CB 1 ATOM 1170 C CG . LYS A 1 154 ? 54.852 45.675 19.240 1.00 19.58 ? 154 LYS A CG 1 ATOM 1171 C CD . LYS A 1 154 ? 56.354 45.774 19.477 1.00 22.18 ? 154 LYS A CD 1 ATOM 1172 C CE . LYS A 1 154 ? 57.036 44.462 19.067 1.00 25.34 ? 154 LYS A CE 1 ATOM 1173 N NZ . LYS A 1 154 ? 56.955 44.267 17.575 1.00 26.38 ? 154 LYS A NZ 1 ATOM 1174 N N . ASN A 1 155 ? 51.254 46.504 20.983 1.00 14.28 ? 155 ASN A N 1 ATOM 1175 C CA . ASN A 1 155 ? 50.427 45.646 21.837 1.00 15.20 ? 155 ASN A CA 1 ATOM 1176 C C . ASN A 1 155 ? 48.938 45.631 21.442 1.00 14.63 ? 155 ASN A C 1 ATOM 1177 O O . ASN A 1 155 ? 48.122 45.011 22.104 1.00 15.53 ? 155 ASN A O 1 ATOM 1178 C CB . ASN A 1 155 ? 50.588 46.011 23.326 1.00 16.78 ? 155 ASN A CB 1 ATOM 1179 C CG . ASN A 1 155 ? 49.712 47.199 23.757 1.00 19.09 ? 155 ASN A CG 1 ATOM 1180 O OD1 . ASN A 1 155 ? 48.993 47.776 22.943 1.00 18.97 ? 155 ASN A OD1 1 ATOM 1181 N ND2 . ASN A 1 155 ? 49.775 47.573 25.042 1.00 20.30 ? 155 ASN A ND2 1 ATOM 1182 N N . GLY A 1 156 ? 48.579 46.369 20.402 1.00 12.79 ? 156 GLY A N 1 ATOM 1183 C CA . GLY A 1 156 ? 47.237 46.252 19.842 1.00 12.80 ? 156 GLY A CA 1 ATOM 1184 C C . GLY A 1 156 ? 46.207 47.174 20.460 1.00 11.38 ? 156 GLY A C 1 ATOM 1185 O O . GLY A 1 156 ? 45.026 47.085 20.083 1.00 13.82 ? 156 GLY A O 1 ATOM 1186 N N . GLN A 1 157 ? 46.606 48.106 21.336 1.00 9.61 ? 157 GLN A N 1 ATOM 1187 C CA . GLN A 1 157 ? 45.619 48.972 21.955 1.00 8.95 ? 157 GLN A CA 1 ATOM 1188 C C . GLN A 1 157 ? 45.209 50.111 21.030 1.00 8.28 ? 157 GLN A C 1 ATOM 1189 O O . GLN A 1 157 ? 44.043 50.465 20.973 1.00 8.21 ? 157 GLN A O 1 ATOM 1190 C CB . GLN A 1 157 ? 46.142 49.577 23.233 1.00 9.26 ? 157 GLN A CB 1 ATOM 1191 C CG . GLN A 1 157 ? 46.075 48.640 24.431 1.00 9.26 ? 157 GLN A CG 1 ATOM 1192 C CD . GLN A 1 157 ? 46.440 49.399 25.671 1.00 8.82 ? 157 GLN A CD 1 ATOM 1193 O OE1 . GLN A 1 157 ? 47.628 49.427 26.017 1.00 10.90 ? 157 GLN A OE1 1 ATOM 1194 N NE2 . GLN A 1 157 ? 45.476 50.094 26.266 1.00 9.29 ? 157 GLN A NE2 1 ATOM 1195 N N . LEU A 1 158 ? 46.192 50.701 20.354 1.00 8.11 ? 158 LEU A N 1 ATOM 1196 C CA A LEU A 1 158 ? 45.889 51.705 19.328 0.50 8.19 ? 158 LEU A CA 1 ATOM 1197 C CA B LEU A 1 158 ? 45.936 51.708 19.332 0.50 8.06 ? 158 LEU A CA 1 ATOM 1198 C C . LEU A 1 158 ? 46.107 51.032 17.986 1.00 8.05 ? 158 LEU A C 1 ATOM 1199 O O . LEU A 1 158 ? 47.187 50.494 17.717 1.00 9.57 ? 158 LEU A O 1 ATOM 1200 C CB A LEU A 1 158 ? 46.762 52.958 19.473 0.50 8.51 ? 158 LEU A CB 1 ATOM 1201 C CB B LEU A 1 158 ? 46.948 52.835 19.465 0.50 8.12 ? 158 LEU A CB 1 ATOM 1202 C CG A LEU A 1 158 ? 46.549 54.224 18.613 0.50 9.33 ? 158 LEU A CG 1 ATOM 1203 C CG B LEU A 1 158 ? 46.961 53.872 18.351 0.50 8.86 ? 158 LEU A CG 1 ATOM 1204 C CD1 A LEU A 1 158 ? 47.544 55.308 19.056 0.50 11.41 ? 158 LEU A CD1 1 ATOM 1205 C CD1 B LEU A 1 158 ? 45.599 54.553 18.316 0.50 8.29 ? 158 LEU A CD1 1 ATOM 1206 C CD2 A LEU A 1 158 ? 46.742 53.962 17.131 0.50 13.98 ? 158 LEU A CD2 1 ATOM 1207 C CD2 B LEU A 1 158 ? 48.090 54.877 18.614 0.50 7.31 ? 158 LEU A CD2 1 ATOM 1208 N N . GLU A 1 159 ? 45.073 51.066 17.148 1.00 7.67 ? 159 GLU A N 1 ATOM 1209 C CA . GLU A 1 159 ? 45.144 50.397 15.858 1.00 7.83 ? 159 GLU A CA 1 ATOM 1210 C C . GLU A 1 159 ? 44.832 51.390 14.754 1.00 6.51 ? 159 GLU A C 1 ATOM 1211 O O . GLU A 1 159 ? 43.842 52.129 14.820 1.00 7.23 ? 159 GLU A O 1 ATOM 1212 C CB . GLU A 1 159 ? 44.130 49.275 15.808 1.00 8.90 ? 159 GLU A CB 1 ATOM 1213 C CG . GLU A 1 159 ? 44.160 48.516 14.515 1.00 11.33 ? 159 GLU A CG 1 ATOM 1214 C CD . GLU A 1 159 ? 43.161 47.406 14.543 1.00 14.67 ? 159 GLU A CD 1 ATOM 1215 O OE1 . GLU A 1 159 ? 43.464 46.404 15.249 1.00 14.30 ? 159 GLU A OE1 1 ATOM 1216 O OE2 . GLU A 1 159 ? 42.091 47.560 13.893 1.00 10.89 ? 159 GLU A OE2 1 ATOM 1217 N N . PHE A 1 160 ? 45.686 51.397 13.739 1.00 6.08 ? 160 PHE A N 1 ATOM 1218 C CA . PHE A 1 160 ? 45.448 52.233 12.574 1.00 6.16 ? 160 PHE A CA 1 ATOM 1219 C C . PHE A 1 160 ? 44.525 51.508 11.624 1.00 6.10 ? 160 PHE A C 1 ATOM 1220 O O . PHE A 1 160 ? 44.694 50.315 11.349 1.00 6.71 ? 160 PHE A O 1 ATOM 1221 C CB . PHE A 1 160 ? 46.780 52.558 11.930 1.00 7.04 ? 160 PHE A CB 1 ATOM 1222 C CG . PHE A 1 160 ? 47.654 53.388 12.820 1.00 6.53 ? 160 PHE A CG 1 ATOM 1223 C CD1 . PHE A 1 160 ? 47.374 54.729 13.008 1.00 7.61 ? 160 PHE A CD1 1 ATOM 1224 C CD2 . PHE A 1 160 ? 48.728 52.804 13.507 1.00 8.16 ? 160 PHE A CD2 1 ATOM 1225 C CE1 . PHE A 1 160 ? 48.156 55.499 13.855 1.00 8.41 ? 160 PHE A CE1 1 ATOM 1226 C CE2 . PHE A 1 160 ? 49.503 53.598 14.341 1.00 9.65 ? 160 PHE A CE2 1 ATOM 1227 C CZ . PHE A 1 160 ? 49.208 54.915 14.501 1.00 8.25 ? 160 PHE A CZ 1 ATOM 1228 N N . VAL A 1 161 ? 43.550 52.242 11.131 1.00 4.96 ? 161 VAL A N 1 ATOM 1229 C CA . VAL A 1 161 ? 42.581 51.747 10.179 1.00 5.75 ? 161 VAL A CA 1 ATOM 1230 C C . VAL A 1 161 ? 42.780 52.543 8.898 1.00 6.48 ? 161 VAL A C 1 ATOM 1231 O O . VAL A 1 161 ? 42.902 53.764 8.929 1.00 7.55 ? 161 VAL A O 1 ATOM 1232 C CB . VAL A 1 161 ? 41.136 51.807 10.747 1.00 5.70 ? 161 VAL A CB 1 ATOM 1233 C CG1 . VAL A 1 161 ? 40.996 50.790 11.879 1.00 6.45 ? 161 VAL A CG1 1 ATOM 1234 C CG2 . VAL A 1 161 ? 40.783 53.163 11.242 1.00 6.89 ? 161 VAL A CG2 1 ATOM 1235 N N . THR A 1 162 ? 42.839 51.788 7.799 1.00 6.61 ? 162 THR A N 1 ATOM 1236 C CA . THR A 1 162 ? 43.192 52.295 6.456 1.00 7.59 ? 162 THR A CA 1 ATOM 1237 C C . THR A 1 162 ? 44.657 52.725 6.394 1.00 6.52 ? 162 THR A C 1 ATOM 1238 O O . THR A 1 162 ? 45.460 52.163 5.660 1.00 7.87 ? 162 THR A O 1 ATOM 1239 C CB . THR A 1 162 ? 42.304 53.444 5.956 1.00 8.79 ? 162 THR A CB 1 ATOM 1240 O OG1 . THR A 1 162 ? 40.917 53.081 6.071 1.00 10.63 ? 162 THR A OG1 1 ATOM 1241 C CG2 . THR A 1 162 ? 42.535 53.622 4.427 1.00 12.35 ? 162 THR A CG2 1 ATOM 1242 N N . GLY A 1 163 ? 44.981 53.747 7.155 1.00 6.67 ? 163 GLY A N 1 ATOM 1243 C CA . GLY A 1 163 ? 46.344 54.224 7.189 1.00 6.17 ? 163 GLY A CA 1 ATOM 1244 C C . GLY A 1 163 ? 46.681 55.161 6.032 1.00 5.19 ? 163 GLY A C 1 ATOM 1245 O O . GLY A 1 163 ? 47.843 55.388 5.744 1.00 6.53 ? 163 GLY A O 1 ATOM 1246 N N . GLY A 1 164 ? 45.670 55.752 5.406 1.00 5.25 ? 164 GLY A N 1 ATOM 1247 C CA . GLY A 1 164 ? 45.957 56.783 4.422 1.00 5.18 ? 164 GLY A CA 1 ATOM 1248 C C . GLY A 1 164 ? 46.259 58.121 5.048 1.00 5.00 ? 164 GLY A C 1 ATOM 1249 O O . GLY A 1 164 ? 45.970 58.373 6.232 1.00 5.94 ? 164 GLY A O 1 ATOM 1250 N N . TRP A 1 165 ? 46.866 58.994 4.259 1.00 4.48 ? 165 TRP A N 1 ATOM 1251 C CA . TRP A 1 165 ? 47.099 60.335 4.750 1.00 4.71 ? 165 TRP A CA 1 ATOM 1252 C C . TRP A 1 165 ? 45.785 60.982 5.205 1.00 4.61 ? 165 TRP A C 1 ATOM 1253 O O . TRP A 1 165 ? 45.753 61.737 6.194 1.00 4.89 ? 165 TRP A O 1 ATOM 1254 C CB . TRP A 1 165 ? 47.719 61.151 3.613 1.00 4.98 ? 165 TRP A CB 1 ATOM 1255 C CG . TRP A 1 165 ? 48.525 62.299 4.072 1.00 4.98 ? 165 TRP A CG 1 ATOM 1256 C CD1 . TRP A 1 165 ? 48.319 63.615 3.773 1.00 6.45 ? 165 TRP A CD1 1 ATOM 1257 C CD2 . TRP A 1 165 ? 49.741 62.240 4.840 1.00 5.71 ? 165 TRP A CD2 1 ATOM 1258 N NE1 . TRP A 1 165 ? 49.308 64.400 4.344 1.00 6.65 ? 165 TRP A NE1 1 ATOM 1259 C CE2 . TRP A 1 165 ? 50.190 63.574 5.005 1.00 5.70 ? 165 TRP A CE2 1 ATOM 1260 C CE3 . TRP A 1 165 ? 50.467 61.200 5.427 1.00 7.25 ? 165 TRP A CE3 1 ATOM 1261 C CZ2 . TRP A 1 165 ? 51.353 63.879 5.776 1.00 7.59 ? 165 TRP A CZ2 1 ATOM 1262 C CZ3 . TRP A 1 165 ? 51.626 61.509 6.164 1.00 8.69 ? 165 TRP A CZ3 1 ATOM 1263 C CH2 . TRP A 1 165 ? 52.038 62.827 6.315 1.00 7.47 ? 165 TRP A CH2 1 ATOM 1264 N N . VAL A 1 166 ? 44.702 60.679 4.498 1.00 3.85 ? 166 VAL A N 1 ATOM 1265 C CA . VAL A 1 166 ? 43.367 61.173 4.798 1.00 4.90 ? 166 VAL A CA 1 ATOM 1266 C C . VAL A 1 166 ? 42.374 60.045 4.612 1.00 5.47 ? 166 VAL A C 1 ATOM 1267 O O . VAL A 1 166 ? 42.766 58.912 4.281 1.00 6.22 ? 166 VAL A O 1 ATOM 1268 C CB . VAL A 1 166 ? 42.967 62.327 3.855 1.00 4.69 ? 166 VAL A CB 1 ATOM 1269 C CG1 . VAL A 1 166 ? 43.955 63.463 3.967 1.00 5.26 ? 166 VAL A CG1 1 ATOM 1270 C CG2 . VAL A 1 166 ? 42.921 61.843 2.386 1.00 6.06 ? 166 VAL A CG2 1 ATOM 1271 N N . MET A 1 167 ? 41.104 60.350 4.831 1.00 5.93 ? 167 MET A N 1 ATOM 1272 C CA . MET A 1 167 ? 40.014 59.452 4.454 1.00 6.26 ? 167 MET A CA 1 ATOM 1273 C C . MET A 1 167 ? 39.413 60.096 3.212 1.00 5.94 ? 167 MET A C 1 ATOM 1274 O O . MET A 1 167 ? 38.685 61.068 3.328 1.00 6.42 ? 167 MET A O 1 ATOM 1275 C CB . MET A 1 167 ? 39.000 59.380 5.594 1.00 5.86 ? 167 MET A CB 1 ATOM 1276 C CG . MET A 1 167 ? 37.726 58.559 5.273 1.00 5.90 ? 167 MET A CG 1 ATOM 1277 S SD . MET A 1 167 ? 36.536 58.735 6.677 1.00 7.75 ? 167 MET A SD 1 ATOM 1278 C CE . MET A 1 167 ? 37.521 58.078 8.034 1.00 8.94 ? 167 MET A CE 1 ATOM 1279 N N . PRO A 1 168 ? 39.754 59.612 2.028 1.00 4.98 ? 168 PRO A N 1 ATOM 1280 C CA . PRO A 1 168 ? 39.478 60.402 0.837 1.00 4.75 ? 168 PRO A CA 1 ATOM 1281 C C . PRO A 1 168 ? 38.040 60.440 0.403 1.00 4.02 ? 168 PRO A C 1 ATOM 1282 O O . PRO A 1 168 ? 37.264 59.496 0.659 1.00 4.83 ? 168 PRO A O 1 ATOM 1283 C CB . PRO A 1 168 ? 40.316 59.718 -0.245 1.00 4.97 ? 168 PRO A CB 1 ATOM 1284 C CG . PRO A 1 168 ? 40.418 58.311 0.211 1.00 6.65 ? 168 PRO A CG 1 ATOM 1285 C CD . PRO A 1 168 ? 40.509 58.367 1.751 1.00 6.53 ? 168 PRO A CD 1 ATOM 1286 N N . ASP A 1 169 ? 37.690 61.518 -0.294 1.00 4.53 ? 169 ASP A N 1 ATOM 1287 C CA . ASP A 1 169 ? 36.491 61.498 -1.102 1.00 5.02 ? 169 ASP A CA 1 ATOM 1288 C C . ASP A 1 169 ? 36.588 60.365 -2.094 1.00 5.52 ? 169 ASP A C 1 ATOM 1289 O O . ASP A 1 169 ? 37.685 59.984 -2.529 1.00 5.47 ? 169 ASP A O 1 ATOM 1290 C CB . ASP A 1 169 ? 36.427 62.829 -1.854 1.00 5.66 ? 169 ASP A CB 1 ATOM 1291 C CG . ASP A 1 169 ? 35.289 62.900 -2.837 1.00 7.07 ? 169 ASP A CG 1 ATOM 1292 O OD1 . ASP A 1 169 ? 34.150 62.447 -2.549 1.00 7.87 ? 169 ASP A OD1 1 ATOM 1293 O OD2 . ASP A 1 169 ? 35.451 63.439 -3.940 1.00 9.70 ? 169 ASP A OD2 1 ATOM 1294 N N . GLU A 1 170 ? 35.427 59.808 -2.410 1.00 4.87 ? 170 GLU A N 1 ATOM 1295 C CA . GLU A 1 170 ? 35.377 58.694 -3.353 1.00 5.74 ? 170 GLU A CA 1 ATOM 1296 C C . GLU A 1 170 ? 34.693 59.065 -4.667 1.00 4.50 ? 170 GLU A C 1 ATOM 1297 O O . GLU A 1 170 ? 34.749 58.277 -5.614 1.00 4.90 ? 170 GLU A O 1 ATOM 1298 C CB . GLU A 1 170 ? 34.740 57.451 -2.688 1.00 5.84 ? 170 GLU A CB 1 ATOM 1299 C CG . GLU A 1 170 ? 35.505 57.066 -1.418 1.00 8.24 ? 170 GLU A CG 1 ATOM 1300 C CD . GLU A 1 170 ? 35.039 55.783 -0.768 1.00 9.24 ? 170 GLU A CD 1 ATOM 1301 O OE1 . GLU A 1 170 ? 34.357 54.983 -1.446 1.00 8.10 ? 170 GLU A OE1 1 ATOM 1302 O OE2 . GLU A 1 170 ? 35.401 55.564 0.405 1.00 9.76 ? 170 GLU A OE2 1 ATOM 1303 N N . ALA A 1 171 ? 34.109 60.256 -4.753 1.00 4.72 ? 171 ALA A N 1 ATOM 1304 C CA . ALA A 1 171 ? 33.379 60.642 -5.949 1.00 4.81 ? 171 ALA A CA 1 ATOM 1305 C C . ALA A 1 171 ? 34.254 61.412 -6.936 1.00 4.45 ? 171 ALA A C 1 ATOM 1306 O O . ALA A 1 171 ? 34.264 61.128 -8.129 1.00 6.33 ? 171 ALA A O 1 ATOM 1307 C CB . ALA A 1 171 ? 32.176 61.464 -5.577 1.00 5.65 ? 171 ALA A CB 1 ATOM 1308 N N . ASN A 1 172 ? 34.982 62.413 -6.431 1.00 4.93 ? 172 ASN A N 1 ATOM 1309 C CA . ASN A 1 172 ? 35.696 63.317 -7.336 1.00 4.66 ? 172 ASN A CA 1 ATOM 1310 C C . ASN A 1 172 ? 37.156 62.952 -7.507 1.00 5.32 ? 172 ASN A C 1 ATOM 1311 O O . ASN A 1 172 ? 37.820 63.413 -8.425 1.00 5.21 ? 172 ASN A O 1 ATOM 1312 C CB . ASN A 1 172 ? 35.674 64.743 -6.755 1.00 4.74 ? 172 ASN A CB 1 ATOM 1313 C CG . ASN A 1 172 ? 34.283 65.288 -6.649 1.00 8.01 ? 172 ASN A CG 1 ATOM 1314 O OD1 . ASN A 1 172 ? 33.588 65.442 -7.646 1.00 12.18 ? 172 ASN A OD1 1 ATOM 1315 N ND2 . ASN A 1 172 ? 33.872 65.622 -5.433 1.00 8.27 ? 172 ASN A ND2 1 ATOM 1316 N N . SER A 1 173 ? 37.660 62.136 -6.595 1.00 4.05 ? 173 SER A N 1 ATOM 1317 C CA . SER A 1 173 ? 39.090 61.816 -6.564 1.00 4.83 ? 173 SER A CA 1 ATOM 1318 C C . SER A 1 173 ? 39.478 60.919 -7.716 1.00 4.99 ? 173 SER A C 1 ATOM 1319 O O . SER A 1 173 ? 38.754 59.991 -8.095 1.00 5.64 ? 173 SER A O 1 ATOM 1320 C CB . SER A 1 173 ? 39.420 61.114 -5.248 1.00 5.53 ? 173 SER A CB 1 ATOM 1321 O OG . SER A 1 173 ? 38.518 60.023 -5.084 1.00 6.15 ? 173 SER A OG 1 ATOM 1322 N N . HIS A 1 174 ? 40.659 61.159 -8.262 1.00 4.00 ? 174 HIS A N 1 ATOM 1323 C CA . HIS A 1 174 ? 41.175 60.266 -9.300 1.00 3.04 ? 174 HIS A CA 1 ATOM 1324 C C . HIS A 1 174 ? 41.816 59.086 -8.583 1.00 3.44 ? 174 HIS A C 1 ATOM 1325 O O . HIS A 1 174 ? 42.464 59.268 -7.545 1.00 4.02 ? 174 HIS A O 1 ATOM 1326 C CB . HIS A 1 174 ? 42.205 60.997 -10.113 1.00 5.19 ? 174 HIS A CB 1 ATOM 1327 C CG . HIS A 1 174 ? 42.477 60.327 -11.385 1.00 5.81 ? 174 HIS A CG 1 ATOM 1328 N ND1 . HIS A 1 174 ? 43.274 59.214 -11.445 1.00 6.34 ? 174 HIS A ND1 1 ATOM 1329 C CD2 . HIS A 1 174 ? 42.037 60.577 -12.651 1.00 6.46 ? 174 HIS A CD2 1 ATOM 1330 C CE1 . HIS A 1 174 ? 43.321 58.804 -12.708 1.00 8.28 ? 174 HIS A CE1 1 ATOM 1331 N NE2 . HIS A 1 174 ? 42.569 59.602 -13.447 1.00 7.79 ? 174 HIS A NE2 1 ATOM 1332 N N . TRP A 1 175 ? 41.707 57.878 -9.138 1.00 3.26 ? 175 TRP A N 1 ATOM 1333 C CA . TRP A 1 175 ? 42.308 56.726 -8.475 1.00 3.22 ? 175 TRP A CA 1 ATOM 1334 C C . TRP A 1 175 ? 43.790 56.890 -8.216 1.00 4.40 ? 175 TRP A C 1 ATOM 1335 O O . TRP A 1 175 ? 44.303 56.355 -7.242 1.00 4.72 ? 175 TRP A O 1 ATOM 1336 C CB . TRP A 1 175 ? 42.057 55.448 -9.278 1.00 4.65 ? 175 TRP A CB 1 ATOM 1337 C CG . TRP A 1 175 ? 42.862 55.256 -10.539 1.00 4.88 ? 175 TRP A CG 1 ATOM 1338 C CD1 . TRP A 1 175 ? 42.526 55.633 -11.829 1.00 5.85 ? 175 TRP A CD1 1 ATOM 1339 C CD2 . TRP A 1 175 ? 44.125 54.624 -10.615 1.00 4.87 ? 175 TRP A CD2 1 ATOM 1340 N NE1 . TRP A 1 175 ? 43.537 55.240 -12.693 1.00 5.46 ? 175 TRP A NE1 1 ATOM 1341 C CE2 . TRP A 1 175 ? 44.521 54.607 -11.979 1.00 5.76 ? 175 TRP A CE2 1 ATOM 1342 C CE3 . TRP A 1 175 ? 44.968 54.026 -9.663 1.00 6.39 ? 175 TRP A CE3 1 ATOM 1343 C CZ2 . TRP A 1 175 ? 45.751 54.053 -12.415 1.00 7.11 ? 175 TRP A CZ2 1 ATOM 1344 C CZ3 . TRP A 1 175 ? 46.166 53.461 -10.107 1.00 6.88 ? 175 TRP A CZ3 1 ATOM 1345 C CH2 . TRP A 1 175 ? 46.548 53.487 -11.471 1.00 7.10 ? 175 TRP A CH2 1 ATOM 1346 N N . ARG A 1 176 ? 44.495 57.583 -9.087 1.00 4.68 ? 176 ARG A N 1 ATOM 1347 C CA . ARG A 1 176 ? 45.925 57.743 -8.922 1.00 4.90 ? 176 ARG A CA 1 ATOM 1348 C C . ARG A 1 176 ? 46.197 58.516 -7.624 1.00 4.86 ? 176 ARG A C 1 ATOM 1349 O O . ARG A 1 176 ? 47.152 58.236 -6.913 1.00 5.16 ? 176 ARG A O 1 ATOM 1350 C CB . ARG A 1 176 ? 46.509 58.467 -10.149 1.00 7.21 ? 176 ARG A CB 1 ATOM 1351 C CG . ARG A 1 176 ? 46.564 57.580 -11.386 1.00 8.92 ? 176 ARG A CG 1 ATOM 1352 C CD . ARG A 1 176 ? 46.565 58.384 -12.694 1.00 12.64 ? 176 ARG A CD 1 ATOM 1353 N NE . ARG A 1 176 ? 47.595 59.402 -12.745 1.00 12.85 ? 176 ARG A NE 1 ATOM 1354 C CZ . ARG A 1 176 ? 47.718 60.269 -13.740 1.00 12.28 ? 176 ARG A CZ 1 ATOM 1355 N NH1 . ARG A 1 176 ? 46.857 60.234 -14.744 1.00 12.58 ? 176 ARG A NH1 1 ATOM 1356 N NH2 . ARG A 1 176 ? 48.649 61.201 -13.693 1.00 12.80 ? 176 ARG A NH2 1 ATOM 1357 N N . ASN A 1 177 ? 45.316 59.457 -7.288 1.00 4.16 ? 177 ASN A N 1 ATOM 1358 C CA . ASN A 1 177 ? 45.509 60.232 -6.058 1.00 4.76 ? 177 ASN A CA 1 ATOM 1359 C C . ASN A 1 177 ? 44.986 59.524 -4.830 1.00 3.90 ? 177 ASN A C 1 ATOM 1360 O O . ASN A 1 177 ? 45.508 59.731 -3.726 1.00 3.98 ? 177 ASN A O 1 ATOM 1361 C CB . ASN A 1 177 ? 44.894 61.626 -6.158 1.00 5.74 ? 177 ASN A CB 1 ATOM 1362 C CG . ASN A 1 177 ? 45.550 62.467 -7.215 1.00 7.26 ? 177 ASN A CG 1 ATOM 1363 O OD1 . ASN A 1 177 ? 46.740 62.314 -7.488 1.00 7.05 ? 177 ASN A OD1 1 ATOM 1364 N ND2 . ASN A 1 177 ? 44.775 63.385 -7.794 1.00 8.76 ? 177 ASN A ND2 1 ATOM 1365 N N . VAL A 1 178 ? 43.995 58.660 -4.993 1.00 3.86 ? 178 VAL A N 1 ATOM 1366 C CA . VAL A 1 178 ? 43.587 57.811 -3.879 1.00 3.79 ? 178 VAL A CA 1 ATOM 1367 C C . VAL A 1 178 ? 44.774 56.911 -3.541 1.00 4.36 ? 178 VAL A C 1 ATOM 1368 O O . VAL A 1 178 ? 45.111 56.724 -2.356 1.00 4.45 ? 178 VAL A O 1 ATOM 1369 C CB . VAL A 1 178 ? 42.377 56.956 -4.283 1.00 4.29 ? 178 VAL A CB 1 ATOM 1370 C CG1 . VAL A 1 178 ? 42.045 56.002 -3.193 1.00 6.06 ? 178 VAL A CG1 1 ATOM 1371 C CG2 . VAL A 1 178 ? 41.181 57.862 -4.537 1.00 7.38 ? 178 VAL A CG2 1 ATOM 1372 N N . LEU A 1 179 ? 45.446 56.354 -4.547 1.00 4.04 ? 179 LEU A N 1 ATOM 1373 C CA . LEU A 1 179 ? 46.611 55.505 -4.294 1.00 4.05 ? 179 LEU A CA 1 ATOM 1374 C C . LEU A 1 179 ? 47.741 56.335 -3.692 1.00 5.15 ? 179 LEU A C 1 ATOM 1375 O O . LEU A 1 179 ? 48.420 55.895 -2.746 1.00 4.78 ? 179 LEU A O 1 ATOM 1376 C CB . LEU A 1 179 ? 47.051 54.792 -5.592 1.00 4.98 ? 179 LEU A CB 1 ATOM 1377 C CG . LEU A 1 179 ? 48.362 54.018 -5.449 1.00 4.64 ? 179 LEU A CG 1 ATOM 1378 C CD1 . LEU A 1 179 ? 48.198 52.934 -4.379 1.00 6.12 ? 179 LEU A CD1 1 ATOM 1379 C CD2 . LEU A 1 179 ? 48.730 53.398 -6.801 1.00 7.23 ? 179 LEU A CD2 1 ATOM 1380 N N . LEU A 1 180 ? 47.938 57.554 -4.189 1.00 4.66 ? 180 LEU A N 1 ATOM 1381 C CA . LEU A 1 180 ? 49.022 58.393 -3.675 1.00 4.71 ? 180 LEU A CA 1 ATOM 1382 C C . LEU A 1 180 ? 48.872 58.623 -2.189 1.00 4.48 ? 180 LEU A C 1 ATOM 1383 O O . LEU A 1 180 ? 49.825 58.491 -1.408 1.00 4.33 ? 180 LEU A O 1 ATOM 1384 C CB . LEU A 1 180 ? 49.030 59.730 -4.453 1.00 5.41 ? 180 LEU A CB 1 ATOM 1385 C CG . LEU A 1 180 ? 50.095 60.725 -4.026 1.00 6.71 ? 180 LEU A CG 1 ATOM 1386 C CD1 . LEU A 1 180 ? 51.381 60.231 -4.617 1.00 10.72 ? 180 LEU A CD1 1 ATOM 1387 C CD2 . LEU A 1 180 ? 49.710 62.072 -4.593 1.00 9.81 ? 180 LEU A CD2 1 ATOM 1388 N N . GLN A 1 181 ? 47.662 59.033 -1.791 1.00 3.96 ? 181 GLN A N 1 ATOM 1389 C CA . GLN A 1 181 ? 47.481 59.351 -0.370 1.00 4.23 ? 181 GLN A CA 1 ATOM 1390 C C . GLN A 1 181 ? 47.563 58.097 0.497 1.00 4.07 ? 181 GLN A C 1 ATOM 1391 O O . GLN A 1 181 ? 48.075 58.137 1.643 1.00 4.61 ? 181 GLN A O 1 ATOM 1392 C CB . GLN A 1 181 ? 46.193 60.153 -0.150 1.00 4.72 ? 181 GLN A CB 1 ATOM 1393 C CG . GLN A 1 181 ? 44.920 59.391 -0.366 1.00 3.90 ? 181 GLN A CG 1 ATOM 1394 C CD . GLN A 1 181 ? 44.540 58.490 0.774 1.00 5.40 ? 181 GLN A CD 1 ATOM 1395 O OE1 . GLN A 1 181 ? 44.788 58.797 1.949 1.00 7.03 ? 181 GLN A OE1 1 ATOM 1396 N NE2 . GLN A 1 181 ? 43.899 57.389 0.422 1.00 6.43 ? 181 GLN A NE2 1 ATOM 1397 N N . LEU A 1 182 ? 47.059 56.969 -0.015 1.00 3.87 ? 182 LEU A N 1 ATOM 1398 C CA . LEU A 1 182 ? 47.174 55.717 0.738 1.00 4.02 ? 182 LEU A CA 1 ATOM 1399 C C . LEU A 1 182 ? 48.639 55.389 0.939 1.00 5.02 ? 182 LEU A C 1 ATOM 1400 O O . LEU A 1 182 ? 49.068 54.987 2.026 1.00 5.20 ? 182 LEU A O 1 ATOM 1401 C CB . LEU A 1 182 ? 46.485 54.569 -0.006 1.00 4.31 ? 182 LEU A CB 1 ATOM 1402 C CG . LEU A 1 182 ? 46.512 53.207 0.690 1.00 4.74 ? 182 LEU A CG 1 ATOM 1403 C CD1 . LEU A 1 182 ? 45.745 53.236 2.020 1.00 7.03 ? 182 LEU A CD1 1 ATOM 1404 C CD2 . LEU A 1 182 ? 45.924 52.165 -0.276 1.00 7.17 ? 182 LEU A CD2 1 ATOM 1405 N N . THR A 1 183 ? 49.425 55.544 -0.113 1.00 4.44 ? 183 THR A N 1 ATOM 1406 C CA . THR A 1 183 ? 50.846 55.188 -0.052 1.00 4.44 ? 183 THR A CA 1 ATOM 1407 C C . THR A 1 183 ? 51.548 56.157 0.883 1.00 5.14 ? 183 THR A C 1 ATOM 1408 O O . THR A 1 183 ? 52.441 55.740 1.644 1.00 5.35 ? 183 THR A O 1 ATOM 1409 C CB . THR A 1 183 ? 51.425 55.287 -1.469 1.00 5.34 ? 183 THR A CB 1 ATOM 1410 O OG1 . THR A 1 183 ? 50.772 54.351 -2.318 1.00 5.87 ? 183 THR A OG1 1 ATOM 1411 C CG2 . THR A 1 183 ? 52.924 54.894 -1.483 1.00 6.79 ? 183 THR A CG2 1 ATOM 1412 N N . GLU A 1 184 ? 51.165 57.413 0.892 1.00 5.23 ? 184 GLU A N 1 ATOM 1413 C CA . GLU A 1 184 ? 51.848 58.382 1.759 1.00 6.01 ? 184 GLU A CA 1 ATOM 1414 C C . GLU A 1 184 ? 51.652 57.999 3.219 1.00 5.89 ? 184 GLU A C 1 ATOM 1415 O O . GLU A 1 184 ? 52.612 57.989 4.011 1.00 6.96 ? 184 GLU A O 1 ATOM 1416 C CB . GLU A 1 184 ? 51.317 59.795 1.507 1.00 6.28 ? 184 GLU A CB 1 ATOM 1417 C CG . GLU A 1 184 ? 52.220 60.919 1.980 1.00 9.24 ? 184 GLU A CG 1 ATOM 1418 C CD . GLU A 1 184 ? 53.603 60.933 1.328 1.00 10.82 ? 184 GLU A CD 1 ATOM 1419 O OE1 . GLU A 1 184 ? 53.789 60.507 0.171 1.00 11.90 ? 184 GLU A OE1 1 ATOM 1420 O OE2 . GLU A 1 184 ? 54.527 61.378 2.016 1.00 13.62 ? 184 GLU A OE2 1 ATOM 1421 N N . GLY A 1 185 ? 50.418 57.700 3.608 1.00 5.13 ? 185 GLY A N 1 ATOM 1422 C CA . GLY A 1 185 ? 50.163 57.311 4.984 1.00 4.89 ? 185 GLY A CA 1 ATOM 1423 C C . GLY A 1 185 ? 50.760 55.973 5.318 1.00 5.30 ? 185 GLY A C 1 ATOM 1424 O O . GLY A 1 185 ? 51.346 55.808 6.416 1.00 5.71 ? 185 GLY A O 1 ATOM 1425 N N . GLN A 1 186 ? 50.616 54.992 4.439 1.00 4.74 ? 186 GLN A N 1 ATOM 1426 C CA . GLN A 1 186 ? 51.105 53.671 4.804 1.00 4.98 ? 186 GLN A CA 1 ATOM 1427 C C . GLN A 1 186 ? 52.623 53.626 4.816 1.00 5.04 ? 186 GLN A C 1 ATOM 1428 O O . GLN A 1 186 ? 53.206 52.876 5.607 1.00 5.08 ? 186 GLN A O 1 ATOM 1429 C CB . GLN A 1 186 ? 50.541 52.568 3.896 1.00 5.65 ? 186 GLN A CB 1 ATOM 1430 C CG . GLN A 1 186 ? 49.058 52.381 4.172 1.00 6.50 ? 186 GLN A CG 1 ATOM 1431 C CD . GLN A 1 186 ? 48.609 51.001 3.914 1.00 8.84 ? 186 GLN A CD 1 ATOM 1432 O OE1 . GLN A 1 186 ? 49.258 50.309 3.160 1.00 11.81 ? 186 GLN A OE1 1 ATOM 1433 N NE2 . GLN A 1 186 ? 47.534 50.564 4.547 1.00 8.38 ? 186 GLN A NE2 1 ATOM 1434 N N . THR A 1 187 ? 53.277 54.382 3.955 1.00 5.68 ? 187 THR A N 1 ATOM 1435 C CA . THR A 1 187 ? 54.739 54.415 3.987 1.00 5.12 ? 187 THR A CA 1 ATOM 1436 C C . THR A 1 187 ? 55.224 55.008 5.296 1.00 5.92 ? 187 THR A C 1 ATOM 1437 O O . THR A 1 187 ? 56.170 54.455 5.910 1.00 6.51 ? 187 THR A O 1 ATOM 1438 C CB . THR A 1 187 ? 55.261 55.164 2.773 1.00 5.94 ? 187 THR A CB 1 ATOM 1439 O OG1 . THR A 1 187 ? 54.795 54.459 1.609 1.00 6.07 ? 187 THR A OG1 1 ATOM 1440 C CG2 . THR A 1 187 ? 56.810 55.117 2.692 1.00 7.77 ? 187 THR A CG2 1 ATOM 1441 N N . TRP A 1 188 ? 54.572 56.080 5.735 1.00 5.39 ? 188 TRP A N 1 ATOM 1442 C CA . TRP A 1 188 ? 54.884 56.669 7.033 1.00 6.73 ? 188 TRP A CA 1 ATOM 1443 C C . TRP A 1 188 ? 54.663 55.608 8.125 1.00 6.30 ? 188 TRP A C 1 ATOM 1444 O O . TRP A 1 188 ? 55.545 55.390 8.986 1.00 6.32 ? 188 TRP A O 1 ATOM 1445 C CB . TRP A 1 188 ? 54.011 57.913 7.268 1.00 6.69 ? 188 TRP A CB 1 ATOM 1446 C CG . TRP A 1 188 ? 54.491 58.672 8.455 1.00 7.72 ? 188 TRP A CG 1 ATOM 1447 C CD1 . TRP A 1 188 ? 55.382 59.705 8.447 1.00 8.47 ? 188 TRP A CD1 1 ATOM 1448 C CD2 . TRP A 1 188 ? 54.181 58.403 9.831 1.00 7.82 ? 188 TRP A CD2 1 ATOM 1449 N NE1 . TRP A 1 188 ? 55.657 60.104 9.741 1.00 8.30 ? 188 TRP A NE1 1 ATOM 1450 C CE2 . TRP A 1 188 ? 54.930 59.326 10.612 1.00 6.71 ? 188 TRP A CE2 1 ATOM 1451 C CE3 . TRP A 1 188 ? 53.337 57.491 10.486 1.00 6.90 ? 188 TRP A CE3 1 ATOM 1452 C CZ2 . TRP A 1 188 ? 54.870 59.355 12.015 1.00 9.14 ? 188 TRP A CZ2 1 ATOM 1453 C CZ3 . TRP A 1 188 ? 53.302 57.500 11.892 1.00 8.79 ? 188 TRP A CZ3 1 ATOM 1454 C CH2 . TRP A 1 188 ? 54.069 58.443 12.632 1.00 7.74 ? 188 TRP A CH2 1 ATOM 1455 N N . LEU A 1 189 ? 53.541 54.903 8.108 1.00 6.25 ? 189 LEU A N 1 ATOM 1456 C CA . LEU A 1 189 ? 53.297 53.946 9.199 1.00 6.81 ? 189 LEU A CA 1 ATOM 1457 C C . LEU A 1 189 ? 54.304 52.847 9.188 1.00 7.43 ? 189 LEU A C 1 ATOM 1458 O O . LEU A 1 189 ? 54.683 52.375 10.295 1.00 7.85 ? 189 LEU A O 1 ATOM 1459 C CB . LEU A 1 189 ? 51.900 53.322 9.090 1.00 7.26 ? 189 LEU A CB 1 ATOM 1460 C CG . LEU A 1 189 ? 50.753 54.208 9.510 1.00 6.01 ? 189 LEU A CG 1 ATOM 1461 C CD1 . LEU A 1 189 ? 49.431 53.484 9.195 1.00 7.75 ? 189 LEU A CD1 1 ATOM 1462 C CD2 . LEU A 1 189 ? 50.854 54.459 11.025 1.00 8.11 ? 189 LEU A CD2 1 ATOM 1463 N N . LYS A 1 190 ? 54.700 52.350 8.021 1.00 7.04 ? 190 LYS A N 1 ATOM 1464 C CA . LYS A 1 190 ? 55.658 51.244 7.992 1.00 9.07 ? 190 LYS A CA 1 ATOM 1465 C C . LYS A 1 190 ? 56.970 51.721 8.594 1.00 9.18 ? 190 LYS A C 1 ATOM 1466 O O . LYS A 1 190 ? 57.570 51.017 9.412 1.00 10.00 ? 190 LYS A O 1 ATOM 1467 C CB . LYS A 1 190 ? 55.899 50.714 6.583 1.00 10.12 ? 190 LYS A CB 1 ATOM 1468 C CG . LYS A 1 190 ? 56.799 49.464 6.569 1.00 12.97 ? 190 LYS A CG 1 ATOM 1469 C CD . LYS A 1 190 ? 56.997 48.946 5.168 1.00 19.00 ? 190 LYS A CD 1 ATOM 1470 C CE . LYS A 1 190 ? 57.641 47.568 5.154 1.00 23.62 ? 190 LYS A CE 1 ATOM 1471 N NZ . LYS A 1 190 ? 58.111 47.273 3.764 1.00 23.03 ? 190 LYS A NZ 1 ATOM 1472 N N . GLN A 1 191 ? 57.412 52.913 8.214 1.00 9.51 ? 191 GLN A N 1 ATOM 1473 C CA . GLN A 1 191 ? 58.708 53.414 8.639 1.00 13.32 ? 191 GLN A CA 1 ATOM 1474 C C . GLN A 1 191 ? 58.728 53.693 10.124 1.00 12.35 ? 191 GLN A C 1 ATOM 1475 O O . GLN A 1 191 ? 59.691 53.327 10.811 1.00 14.76 ? 191 GLN A O 1 ATOM 1476 C CB . GLN A 1 191 ? 59.044 54.683 7.857 1.00 13.03 ? 191 GLN A CB 1 ATOM 1477 C CG . GLN A 1 191 ? 60.432 55.267 8.187 1.00 18.97 ? 191 GLN A CG 1 ATOM 1478 C CD . GLN A 1 191 ? 60.767 56.485 7.326 1.00 19.60 ? 191 GLN A CD 1 ATOM 1479 O OE1 . GLN A 1 191 ? 60.029 56.820 6.379 1.00 27.96 ? 191 GLN A OE1 1 ATOM 1480 N NE2 . GLN A 1 191 ? 61.860 57.164 7.665 1.00 28.91 ? 191 GLN A NE2 1 ATOM 1481 N N . PHE A 1 192 ? 57.711 54.358 10.648 1.00 10.54 ? 192 PHE A N 1 ATOM 1482 C CA . PHE A 1 192 ? 57.741 54.810 12.036 1.00 10.83 ? 192 PHE A CA 1 ATOM 1483 C C . PHE A 1 192 ? 57.044 53.938 13.045 1.00 12.30 ? 192 PHE A C 1 ATOM 1484 O O . PHE A 1 192 ? 57.474 53.913 14.215 1.00 14.00 ? 192 PHE A O 1 ATOM 1485 C CB . PHE A 1 192 ? 57.247 56.251 12.121 1.00 10.50 ? 192 PHE A CB 1 ATOM 1486 C CG . PHE A 1 192 ? 58.146 57.202 11.392 1.00 10.67 ? 192 PHE A CG 1 ATOM 1487 C CD1 . PHE A 1 192 ? 59.391 57.546 11.944 1.00 11.57 ? 192 PHE A CD1 1 ATOM 1488 C CD2 . PHE A 1 192 ? 57.829 57.686 10.134 1.00 12.13 ? 192 PHE A CD2 1 ATOM 1489 C CE1 . PHE A 1 192 ? 60.277 58.404 11.254 1.00 12.75 ? 192 PHE A CE1 1 ATOM 1490 C CE2 . PHE A 1 192 ? 58.712 58.538 9.425 1.00 12.74 ? 192 PHE A CE2 1 ATOM 1491 C CZ . PHE A 1 192 ? 59.954 58.902 10.011 1.00 12.14 ? 192 PHE A CZ 1 ATOM 1492 N N . MET A 1 193 ? 55.988 53.229 12.633 1.00 9.85 ? 193 MET A N 1 ATOM 1493 C CA A MET A 1 193 ? 55.161 52.429 13.540 0.50 10.01 ? 193 MET A CA 1 ATOM 1494 C CA B MET A 1 193 ? 55.195 52.432 13.561 0.50 10.17 ? 193 MET A CA 1 ATOM 1495 C C . MET A 1 193 ? 55.303 50.938 13.289 1.00 10.14 ? 193 MET A C 1 ATOM 1496 O O . MET A 1 193 ? 54.770 50.129 14.073 1.00 11.50 ? 193 MET A O 1 ATOM 1497 C CB A MET A 1 193 ? 53.678 52.809 13.423 0.50 10.05 ? 193 MET A CB 1 ATOM 1498 C CB B MET A 1 193 ? 53.734 52.890 13.535 0.50 10.21 ? 193 MET A CB 1 ATOM 1499 C CG A MET A 1 193 ? 53.333 54.125 14.085 0.50 9.24 ? 193 MET A CG 1 ATOM 1500 C CG B MET A 1 193 ? 53.600 54.403 13.641 0.50 10.28 ? 193 MET A CG 1 ATOM 1501 S SD A MET A 1 193 ? 53.484 54.104 15.898 0.50 10.88 ? 193 MET A SD 1 ATOM 1502 S SD B MET A 1 193 ? 54.465 55.166 15.034 0.50 15.65 ? 193 MET A SD 1 ATOM 1503 C CE A MET A 1 193 ? 54.435 55.613 16.228 0.50 13.50 ? 193 MET A CE 1 ATOM 1504 C CE B MET A 1 193 ? 53.415 54.699 16.318 0.50 11.73 ? 193 MET A CE 1 ATOM 1505 N N . ASN A 1 194 ? 55.977 50.578 12.198 1.00 9.84 ? 194 ASN A N 1 ATOM 1506 C CA . ASN A 1 194 ? 56.156 49.190 11.774 1.00 10.86 ? 194 ASN A CA 1 ATOM 1507 C C . ASN A 1 194 ? 54.853 48.393 11.659 1.00 10.66 ? 194 ASN A C 1 ATOM 1508 O O . ASN A 1 194 ? 54.752 47.234 12.120 1.00 12.02 ? 194 ASN A O 1 ATOM 1509 C CB . ASN A 1 194 ? 57.109 48.479 12.750 1.00 12.40 ? 194 ASN A CB 1 ATOM 1510 C CG . ASN A 1 194 ? 57.551 47.123 12.245 1.00 15.10 ? 194 ASN A CG 1 ATOM 1511 O OD1 . ASN A 1 194 ? 57.633 46.903 11.037 1.00 15.13 ? 194 ASN A OD1 1 ATOM 1512 N ND2 . ASN A 1 194 ? 57.819 46.193 13.178 1.00 17.14 ? 194 ASN A ND2 1 ATOM 1513 N N . VAL A 1 195 ? 53.823 49.020 11.088 1.00 9.81 ? 195 VAL A N 1 ATOM 1514 C CA . VAL A 1 195 ? 52.547 48.340 10.895 1.00 9.82 ? 195 VAL A CA 1 ATOM 1515 C C . VAL A 1 195 ? 52.003 48.742 9.540 1.00 8.50 ? 195 VAL A C 1 ATOM 1516 O O . VAL A 1 195 ? 52.262 49.869 9.094 1.00 8.51 ? 195 VAL A O 1 ATOM 1517 C CB . VAL A 1 195 ? 51.479 48.717 11.991 1.00 10.70 ? 195 VAL A CB 1 ATOM 1518 C CG1 . VAL A 1 195 ? 51.828 48.179 13.386 1.00 15.27 ? 195 VAL A CG1 1 ATOM 1519 C CG2 . VAL A 1 195 ? 51.192 50.212 12.040 1.00 11.36 ? 195 VAL A CG2 1 ATOM 1520 N N . THR A 1 196 ? 51.239 47.825 8.935 1.00 8.88 ? 196 THR A N 1 ATOM 1521 C CA . THR A 1 196 ? 50.519 48.105 7.697 1.00 9.41 ? 196 THR A CA 1 ATOM 1522 C C . THR A 1 196 ? 49.077 47.635 7.872 1.00 8.33 ? 196 THR A C 1 ATOM 1523 O O . THR A 1 196 ? 48.839 46.419 7.938 1.00 8.94 ? 196 THR A O 1 ATOM 1524 C CB . THR A 1 196 ? 51.170 47.335 6.513 1.00 10.43 ? 196 THR A CB 1 ATOM 1525 O OG1 . THR A 1 196 ? 52.531 47.784 6.323 1.00 12.37 ? 196 THR A OG1 1 ATOM 1526 C CG2 . THR A 1 196 ? 50.477 47.640 5.207 1.00 12.44 ? 196 THR A CG2 1 ATOM 1527 N N . PRO A 1 197 ? 48.123 48.558 7.972 1.00 7.04 ? 197 PRO A N 1 ATOM 1528 C CA . PRO A 1 197 ? 46.724 48.171 8.161 1.00 6.44 ? 197 PRO A CA 1 ATOM 1529 C C . PRO A 1 197 ? 46.201 47.309 7.034 1.00 7.61 ? 197 PRO A C 1 ATOM 1530 O O . PRO A 1 197 ? 46.555 47.568 5.883 1.00 7.08 ? 197 PRO A O 1 ATOM 1531 C CB . PRO A 1 197 ? 45.988 49.527 8.165 1.00 7.90 ? 197 PRO A CB 1 ATOM 1532 C CG . PRO A 1 197 ? 46.999 50.471 8.658 1.00 8.17 ? 197 PRO A CG 1 ATOM 1533 C CD . PRO A 1 197 ? 48.298 50.016 8.085 1.00 7.91 ? 197 PRO A CD 1 ATOM 1534 N N . THR A 1 198 ? 45.350 46.334 7.373 1.00 6.08 ? 198 THR A N 1 ATOM 1535 C CA . THR A 1 198 ? 44.695 45.512 6.353 1.00 6.52 ? 198 THR A CA 1 ATOM 1536 C C . THR A 1 198 ? 43.169 45.662 6.440 1.00 5.44 ? 198 THR A C 1 ATOM 1537 O O . THR A 1 198 ? 42.455 44.972 5.725 1.00 6.22 ? 198 THR A O 1 ATOM 1538 C CB . THR A 1 198 ? 45.057 44.031 6.478 1.00 8.39 ? 198 THR A CB 1 ATOM 1539 O OG1 . THR A 1 198 ? 44.659 43.577 7.785 1.00 10.76 ? 198 THR A OG1 1 ATOM 1540 C CG2 . THR A 1 198 ? 46.557 43.784 6.386 1.00 10.17 ? 198 THR A CG2 1 ATOM 1541 N N . ALA A 1 199 ? 42.689 46.554 7.310 1.00 5.75 ? 199 ALA A N 1 ATOM 1542 C CA . ALA A 1 199 ? 41.258 46.888 7.403 1.00 5.85 ? 199 ALA A CA 1 ATOM 1543 C C . ALA A 1 199 ? 41.112 48.369 7.174 1.00 7.20 ? 199 ALA A C 1 ATOM 1544 O O . ALA A 1 199 ? 41.877 49.156 7.737 1.00 6.55 ? 199 ALA A O 1 ATOM 1545 C CB . ALA A 1 199 ? 40.727 46.564 8.807 1.00 8.00 ? 199 ALA A CB 1 ATOM 1546 N N . SER A 1 200 ? 40.130 48.723 6.351 1.00 6.24 ? 200 SER A N 1 ATOM 1547 C CA . SER A 1 200 ? 39.854 50.118 6.049 1.00 7.10 ? 200 SER A CA 1 ATOM 1548 C C . SER A 1 200 ? 38.556 50.589 6.734 1.00 6.84 ? 200 SER A C 1 ATOM 1549 O O . SER A 1 200 ? 37.618 49.796 6.917 1.00 7.17 ? 200 SER A O 1 ATOM 1550 C CB . SER A 1 200 ? 39.749 50.263 4.546 1.00 7.38 ? 200 SER A CB 1 ATOM 1551 O OG . SER A 1 200 ? 39.430 51.606 4.188 1.00 11.17 ? 200 SER A OG 1 ATOM 1552 N N . TRP A 1 201 ? 38.531 51.875 7.083 1.00 6.88 ? 201 TRP A N 1 ATOM 1553 C CA . TRP A 1 201 ? 37.427 52.520 7.807 1.00 7.32 ? 201 TRP A CA 1 ATOM 1554 C C . TRP A 1 201 ? 37.098 53.798 7.065 1.00 7.54 ? 201 TRP A C 1 ATOM 1555 O O . TRP A 1 201 ? 37.903 54.754 7.057 1.00 8.77 ? 201 TRP A O 1 ATOM 1556 C CB . TRP A 1 201 ? 37.935 52.829 9.201 1.00 7.54 ? 201 TRP A CB 1 ATOM 1557 C CG . TRP A 1 201 ? 37.146 53.636 10.163 1.00 7.16 ? 201 TRP A CG 1 ATOM 1558 C CD1 . TRP A 1 201 ? 37.332 54.965 10.472 1.00 7.66 ? 201 TRP A CD1 1 ATOM 1559 C CD2 . TRP A 1 201 ? 36.188 53.149 11.098 1.00 7.29 ? 201 TRP A CD2 1 ATOM 1560 N NE1 . TRP A 1 201 ? 36.511 55.329 11.513 1.00 8.35 ? 201 TRP A NE1 1 ATOM 1561 C CE2 . TRP A 1 201 ? 35.802 54.239 11.920 1.00 7.64 ? 201 TRP A CE2 1 ATOM 1562 C CE3 . TRP A 1 201 ? 35.598 51.908 11.312 1.00 7.96 ? 201 TRP A CE3 1 ATOM 1563 C CZ2 . TRP A 1 201 ? 34.860 54.115 12.937 1.00 8.75 ? 201 TRP A CZ2 1 ATOM 1564 C CZ3 . TRP A 1 201 ? 34.644 51.771 12.322 1.00 9.53 ? 201 TRP A CZ3 1 ATOM 1565 C CH2 . TRP A 1 201 ? 34.301 52.881 13.119 1.00 9.17 ? 201 TRP A CH2 1 ATOM 1566 N N . ALA A 1 202 ? 35.941 53.818 6.407 1.00 6.25 ? 202 ALA A N 1 ATOM 1567 C CA . ALA A 1 202 ? 35.513 55.006 5.657 1.00 6.52 ? 202 ALA A CA 1 ATOM 1568 C C . ALA A 1 202 ? 34.109 55.383 6.107 1.00 6.29 ? 202 ALA A C 1 ATOM 1569 O O . ALA A 1 202 ? 33.116 54.969 5.531 1.00 7.46 ? 202 ALA A O 1 ATOM 1570 C CB . ALA A 1 202 ? 35.545 54.742 4.162 1.00 7.66 ? 202 ALA A CB 1 ATOM 1571 N N . ILE A 1 203 ? 34.035 56.170 7.171 1.00 5.39 ? 203 ILE A N 1 ATOM 1572 C CA . ILE A 1 203 ? 32.745 56.464 7.809 1.00 6.21 ? 203 ILE A CA 1 ATOM 1573 C C . ILE A 1 203 ? 32.087 57.737 7.314 1.00 6.05 ? 203 ILE A C 1 ATOM 1574 O O . ILE A 1 203 ? 30.903 57.946 7.561 1.00 6.89 ? 203 ILE A O 1 ATOM 1575 C CB . ILE A 1 203 ? 32.856 56.472 9.355 1.00 5.61 ? 203 ILE A CB 1 ATOM 1576 C CG1 . ILE A 1 203 ? 33.928 57.456 9.829 1.00 6.35 ? 203 ILE A CG1 1 ATOM 1577 C CG2 . ILE A 1 203 ? 33.102 55.034 9.820 1.00 7.94 ? 203 ILE A CG2 1 ATOM 1578 C CD1 . ILE A 1 203 ? 33.884 57.763 11.304 1.00 6.41 ? 203 ILE A CD1 1 ATOM 1579 N N . ASP A 1 204 ? 32.839 58.578 6.597 1.00 6.48 ? 204 ASP A N 1 ATOM 1580 C CA . ASP A 1 204 ? 32.327 59.883 6.243 1.00 6.99 ? 204 ASP A CA 1 ATOM 1581 C C . ASP A 1 204 ? 32.311 60.285 4.756 1.00 6.60 ? 204 ASP A C 1 ATOM 1582 O O . ASP A 1 204 ? 31.581 61.246 4.460 1.00 8.43 ? 204 ASP A O 1 ATOM 1583 C CB . ASP A 1 204 ? 33.023 60.973 7.076 1.00 6.72 ? 204 ASP A CB 1 ATOM 1584 C CG . ASP A 1 204 ? 32.157 62.223 7.300 1.00 8.00 ? 204 ASP A CG 1 ATOM 1585 O OD1 . ASP A 1 204 ? 30.887 62.111 7.350 1.00 8.81 ? 204 ASP A OD1 1 ATOM 1586 O OD2 . ASP A 1 204 ? 32.654 63.347 7.507 1.00 7.80 ? 204 ASP A OD2 1 ATOM 1587 N N . PRO A 1 205 ? 33.001 59.631 3.814 1.00 6.32 ? 205 PRO A N 1 ATOM 1588 C CA . PRO A 1 205 ? 32.863 60.136 2.419 1.00 6.92 ? 205 PRO A CA 1 ATOM 1589 C C . PRO A 1 205 ? 31.413 60.009 1.948 1.00 6.28 ? 205 PRO A C 1 ATOM 1590 O O . PRO A 1 205 ? 30.641 59.149 2.393 1.00 6.63 ? 205 PRO A O 1 ATOM 1591 C CB . PRO A 1 205 ? 33.787 59.236 1.603 1.00 8.10 ? 205 PRO A CB 1 ATOM 1592 C CG . PRO A 1 205 ? 34.782 58.704 2.643 1.00 11.86 ? 205 PRO A CG 1 ATOM 1593 C CD . PRO A 1 205 ? 33.904 58.461 3.878 1.00 8.88 ? 205 PRO A CD 1 ATOM 1594 N N . PHE A 1 206 ? 31.025 60.896 1.025 1.00 5.17 ? 206 PHE A N 1 ATOM 1595 C CA . PHE A 1 206 ? 29.594 61.069 0.784 1.00 6.68 ? 206 PHE A CA 1 ATOM 1596 C C . PHE A 1 206 ? 29.117 60.161 -0.357 1.00 6.30 ? 206 PHE A C 1 ATOM 1597 O O . PHE A 1 206 ? 28.898 60.604 -1.488 1.00 6.19 ? 206 PHE A O 1 ATOM 1598 C CB . PHE A 1 206 ? 29.281 62.538 0.504 1.00 6.55 ? 206 PHE A CB 1 ATOM 1599 C CG . PHE A 1 206 ? 30.082 63.527 1.357 1.00 6.59 ? 206 PHE A CG 1 ATOM 1600 C CD1 . PHE A 1 206 ? 30.299 63.305 2.706 1.00 6.12 ? 206 PHE A CD1 1 ATOM 1601 C CD2 . PHE A 1 206 ? 30.634 64.658 0.753 1.00 6.86 ? 206 PHE A CD2 1 ATOM 1602 C CE1 . PHE A 1 206 ? 31.051 64.233 3.458 1.00 7.84 ? 206 PHE A CE1 1 ATOM 1603 C CE2 . PHE A 1 206 ? 31.378 65.564 1.507 1.00 6.64 ? 206 PHE A CE2 1 ATOM 1604 C CZ . PHE A 1 206 ? 31.575 65.343 2.839 1.00 7.43 ? 206 PHE A CZ 1 ATOM 1605 N N . GLY A 1 207 ? 29.004 58.876 -0.039 1.00 5.87 ? 207 GLY A N 1 ATOM 1606 C CA . GLY A 1 207 ? 28.816 57.848 -1.043 1.00 6.13 ? 207 GLY A CA 1 ATOM 1607 C C . GLY A 1 207 ? 30.146 57.141 -1.275 1.00 5.45 ? 207 GLY A C 1 ATOM 1608 O O . GLY A 1 207 ? 31.246 57.667 -0.988 1.00 6.22 ? 207 GLY A O 1 ATOM 1609 N N . HIS A 1 208 ? 30.080 55.931 -1.813 1.00 5.12 ? 208 HIS A N 1 ATOM 1610 C CA . HIS A 1 208 ? 31.249 55.048 -1.895 1.00 5.17 ? 208 HIS A CA 1 ATOM 1611 C C . HIS A 1 208 ? 31.440 54.418 -3.282 1.00 5.05 ? 208 HIS A C 1 ATOM 1612 O O . HIS A 1 208 ? 30.467 54.111 -3.984 1.00 5.43 ? 208 HIS A O 1 ATOM 1613 C CB . HIS A 1 208 ? 31.151 53.929 -0.818 1.00 5.82 ? 208 HIS A CB 1 ATOM 1614 C CG . HIS A 1 208 ? 31.198 54.432 0.595 1.00 6.02 ? 208 HIS A CG 1 ATOM 1615 N ND1 . HIS A 1 208 ? 32.385 54.701 1.242 1.00 8.99 ? 208 HIS A ND1 1 ATOM 1616 C CD2 . HIS A 1 208 ? 30.204 54.742 1.459 1.00 7.88 ? 208 HIS A CD2 1 ATOM 1617 C CE1 . HIS A 1 208 ? 32.101 55.140 2.463 1.00 8.78 ? 208 HIS A CE1 1 ATOM 1618 N NE2 . HIS A 1 208 ? 30.794 55.164 2.622 1.00 8.13 ? 208 HIS A NE2 1 ATOM 1619 N N . SER A 1 209 ? 32.714 54.276 -3.651 1.00 4.21 ? 209 SER A N 1 ATOM 1620 C CA . SER A 1 209 ? 33.110 53.832 -4.968 1.00 4.65 ? 209 SER A CA 1 ATOM 1621 C C . SER A 1 209 ? 33.814 52.483 -4.914 1.00 4.39 ? 209 SER A C 1 ATOM 1622 O O . SER A 1 209 ? 34.615 52.248 -4.016 1.00 5.18 ? 209 SER A O 1 ATOM 1623 C CB . SER A 1 209 ? 34.114 54.829 -5.519 1.00 6.23 ? 209 SER A CB 1 ATOM 1624 O OG . SER A 1 209 ? 34.582 54.327 -6.767 1.00 5.78 ? 209 SER A OG 1 ATOM 1625 N N . PRO A 1 210 ? 33.568 51.605 -5.891 1.00 4.31 ? 210 PRO A N 1 ATOM 1626 C CA . PRO A 1 210 ? 34.286 50.321 -5.931 1.00 4.59 ? 210 PRO A CA 1 ATOM 1627 C C . PRO A 1 210 ? 35.755 50.521 -6.272 1.00 4.99 ? 210 PRO A C 1 ATOM 1628 O O . PRO A 1 210 ? 36.536 49.579 -6.193 1.00 5.13 ? 210 PRO A O 1 ATOM 1629 C CB . PRO A 1 210 ? 33.564 49.547 -7.041 1.00 4.50 ? 210 PRO A CB 1 ATOM 1630 C CG . PRO A 1 210 ? 32.975 50.635 -7.899 1.00 5.51 ? 210 PRO A CG 1 ATOM 1631 C CD . PRO A 1 210 ? 32.571 51.738 -6.969 1.00 4.51 ? 210 PRO A CD 1 ATOM 1632 N N . THR A 1 211 ? 36.164 51.737 -6.642 1.00 4.79 ? 211 THR A N 1 ATOM 1633 C CA . THR A 1 211 ? 37.588 51.979 -6.806 1.00 5.42 ? 211 THR A CA 1 ATOM 1634 C C . THR A 1 211 ? 38.342 51.730 -5.515 1.00 5.37 ? 211 THR A C 1 ATOM 1635 O O . THR A 1 211 ? 39.519 51.357 -5.544 1.00 5.51 ? 211 THR A O 1 ATOM 1636 C CB . THR A 1 211 ? 37.788 53.421 -7.279 1.00 6.37 ? 211 THR A CB 1 ATOM 1637 O OG1 . THR A 1 211 ? 37.283 53.471 -8.618 1.00 7.49 ? 211 THR A OG1 1 ATOM 1638 C CG2 . THR A 1 211 ? 39.301 53.760 -7.324 1.00 8.24 ? 211 THR A CG2 1 ATOM 1639 N N A MET A 1 212 ? 37.719 51.992 -4.382 0.50 4.97 ? 212 MET A N 1 ATOM 1640 N N B MET A 1 212 ? 37.715 51.992 -4.388 0.50 5.42 ? 212 MET A N 1 ATOM 1641 C CA A MET A 1 212 ? 38.370 51.723 -3.109 0.50 5.31 ? 212 MET A CA 1 ATOM 1642 C CA B MET A 1 212 ? 38.365 51.723 -3.123 0.50 6.36 ? 212 MET A CA 1 ATOM 1643 C C A MET A 1 212 ? 38.726 50.263 -2.844 0.50 5.46 ? 212 MET A C 1 ATOM 1644 C C B MET A 1 212 ? 38.722 50.265 -2.843 0.50 5.87 ? 212 MET A C 1 ATOM 1645 O O A MET A 1 212 ? 39.882 49.966 -2.631 0.50 5.63 ? 212 MET A O 1 ATOM 1646 O O B MET A 1 212 ? 39.880 49.970 -2.628 0.50 6.10 ? 212 MET A O 1 ATOM 1647 C CB A MET A 1 212 ? 37.571 52.312 -1.954 0.50 6.07 ? 212 MET A CB 1 ATOM 1648 C CB B MET A 1 212 ? 37.613 52.371 -1.971 0.50 7.26 ? 212 MET A CB 1 ATOM 1649 C CG A MET A 1 212 ? 37.299 53.766 -2.058 0.50 5.37 ? 212 MET A CG 1 ATOM 1650 C CG B MET A 1 212 ? 38.445 52.395 -0.710 0.50 10.48 ? 212 MET A CG 1 ATOM 1651 S SD A MET A 1 212 ? 38.773 54.780 -2.234 0.50 8.11 ? 212 MET A SD 1 ATOM 1652 S SD B MET A 1 212 ? 39.754 53.605 -0.884 0.50 17.40 ? 212 MET A SD 1 ATOM 1653 C CE A MET A 1 212 ? 39.552 54.636 -0.656 0.50 8.43 ? 212 MET A CE 1 ATOM 1654 C CE B MET A 1 212 ? 38.892 54.716 -2.098 0.50 7.06 ? 212 MET A CE 1 ATOM 1655 N N . PRO A 1 213 ? 37.760 49.348 -2.881 1.00 4.91 ? 213 PRO A N 1 ATOM 1656 C CA . PRO A 1 213 ? 38.171 47.939 -2.749 1.00 4.86 ? 213 PRO A CA 1 ATOM 1657 C C . PRO A 1 213 ? 39.158 47.521 -3.838 1.00 6.55 ? 213 PRO A C 1 ATOM 1658 O O . PRO A 1 213 ? 40.023 46.659 -3.580 1.00 6.00 ? 213 PRO A O 1 ATOM 1659 C CB . PRO A 1 213 ? 36.863 47.122 -2.807 1.00 6.23 ? 213 PRO A CB 1 ATOM 1660 C CG . PRO A 1 213 ? 35.885 48.080 -3.466 1.00 6.63 ? 213 PRO A CG 1 ATOM 1661 C CD . PRO A 1 213 ? 36.277 49.448 -2.936 1.00 6.07 ? 213 PRO A CD 1 ATOM 1662 N N . TYR A 1 214 ? 39.035 48.076 -5.055 1.00 6.41 ? 214 TYR A N 1 ATOM 1663 C CA . TYR A 1 214 ? 39.992 47.737 -6.117 1.00 6.63 ? 214 TYR A CA 1 ATOM 1664 C C . TYR A 1 214 ? 41.414 48.020 -5.662 1.00 6.61 ? 214 TYR A C 1 ATOM 1665 O O . TYR A 1 214 ? 42.305 47.155 -5.731 1.00 6.84 ? 214 TYR A O 1 ATOM 1666 C CB . TYR A 1 214 ? 39.691 48.552 -7.353 1.00 7.59 ? 214 TYR A CB 1 ATOM 1667 C CG . TYR A 1 214 ? 40.603 48.340 -8.557 1.00 8.85 ? 214 TYR A CG 1 ATOM 1668 C CD1 . TYR A 1 214 ? 40.305 47.368 -9.476 1.00 12.41 ? 214 TYR A CD1 1 ATOM 1669 C CD2 . TYR A 1 214 ? 41.720 49.110 -8.750 1.00 7.25 ? 214 TYR A CD2 1 ATOM 1670 C CE1 . TYR A 1 214 ? 41.107 47.170 -10.589 1.00 13.53 ? 214 TYR A CE1 1 ATOM 1671 C CE2 . TYR A 1 214 ? 42.540 48.917 -9.839 1.00 8.25 ? 214 TYR A CE2 1 ATOM 1672 C CZ . TYR A 1 214 ? 42.220 47.954 -10.745 1.00 11.36 ? 214 TYR A CZ 1 ATOM 1673 O OH . TYR A 1 214 ? 42.999 47.766 -11.874 1.00 12.27 ? 214 TYR A OH 1 ATOM 1674 N N . ILE A 1 215 ? 41.646 49.245 -5.202 1.00 5.47 ? 215 ILE A N 1 ATOM 1675 C CA . ILE A 1 215 ? 42.983 49.628 -4.781 1.00 4.99 ? 215 ILE A CA 1 ATOM 1676 C C . ILE A 1 215 ? 43.380 48.929 -3.478 1.00 5.01 ? 215 ILE A C 1 ATOM 1677 O O . ILE A 1 215 ? 44.522 48.481 -3.330 1.00 6.19 ? 215 ILE A O 1 ATOM 1678 C CB . ILE A 1 215 ? 43.044 51.156 -4.574 1.00 4.67 ? 215 ILE A CB 1 ATOM 1679 C CG1 . ILE A 1 215 ? 42.885 51.886 -5.904 1.00 5.92 ? 215 ILE A CG1 1 ATOM 1680 C CG2 . ILE A 1 215 ? 44.351 51.552 -3.825 1.00 7.13 ? 215 ILE A CG2 1 ATOM 1681 C CD1 . ILE A 1 215 ? 42.781 53.353 -5.709 1.00 9.94 ? 215 ILE A CD1 1 ATOM 1682 N N . LEU A 1 216 ? 42.460 48.859 -2.528 1.00 4.19 ? 216 LEU A N 1 ATOM 1683 C CA . LEU A 1 216 ? 42.793 48.259 -1.248 1.00 4.89 ? 216 LEU A CA 1 ATOM 1684 C C . LEU A 1 216 ? 43.159 46.799 -1.384 1.00 5.23 ? 216 LEU A C 1 ATOM 1685 O O . LEU A 1 216 ? 44.153 46.344 -0.778 1.00 5.25 ? 216 LEU A O 1 ATOM 1686 C CB . LEU A 1 216 ? 41.641 48.406 -0.273 1.00 5.39 ? 216 LEU A CB 1 ATOM 1687 C CG . LEU A 1 216 ? 41.274 49.835 0.124 1.00 5.70 ? 216 LEU A CG 1 ATOM 1688 C CD1 . LEU A 1 216 ? 39.965 49.797 0.896 1.00 7.44 ? 216 LEU A CD1 1 ATOM 1689 C CD2 . LEU A 1 216 ? 42.345 50.497 0.983 1.00 7.96 ? 216 LEU A CD2 1 ATOM 1690 N N . GLN A 1 217 ? 42.383 46.048 -2.162 1.00 5.33 ? 217 GLN A N 1 ATOM 1691 C CA . GLN A 1 217 ? 42.684 44.635 -2.315 1.00 5.94 ? 217 GLN A CA 1 ATOM 1692 C C . GLN A 1 217 ? 44.061 44.396 -2.943 1.00 6.93 ? 217 GLN A C 1 ATOM 1693 O O . GLN A 1 217 ? 44.701 43.380 -2.665 1.00 8.78 ? 217 GLN A O 1 ATOM 1694 C CB . GLN A 1 217 ? 41.534 43.958 -3.066 1.00 8.52 ? 217 GLN A CB 1 ATOM 1695 C CG . GLN A 1 217 ? 41.567 42.413 -3.128 1.00 9.22 ? 217 GLN A CG 1 ATOM 1696 C CD . GLN A 1 217 ? 42.469 41.879 -4.213 1.00 13.79 ? 217 GLN A CD 1 ATOM 1697 O OE1 . GLN A 1 217 ? 42.636 42.513 -5.248 1.00 13.92 ? 217 GLN A OE1 1 ATOM 1698 N NE2 . GLN A 1 217 ? 43.013 40.681 -4.002 1.00 16.31 ? 217 GLN A NE2 1 ATOM 1699 N N . LYS A 1 218 ? 44.497 45.285 -3.826 1.00 5.76 ? 218 LYS A N 1 ATOM 1700 C CA . LYS A 1 218 ? 45.819 45.185 -4.458 1.00 5.83 ? 218 LYS A CA 1 ATOM 1701 C C . LYS A 1 218 ? 46.904 45.831 -3.592 1.00 6.32 ? 218 LYS A C 1 ATOM 1702 O O . LYS A 1 218 ? 48.069 45.876 -3.970 1.00 5.95 ? 218 LYS A O 1 ATOM 1703 C CB . LYS A 1 218 ? 45.771 45.874 -5.809 1.00 7.16 ? 218 LYS A CB 1 ATOM 1704 C CG . LYS A 1 218 ? 44.905 45.152 -6.813 1.00 8.69 ? 218 LYS A CG 1 ATOM 1705 C CD . LYS A 1 218 ? 44.664 45.989 -8.068 1.00 7.73 ? 218 LYS A CD 1 ATOM 1706 C CE . LYS A 1 218 ? 44.311 45.109 -9.278 1.00 14.00 ? 218 LYS A CE 1 ATOM 1707 N NZ . LYS A 1 218 ? 43.226 44.094 -9.099 1.00 14.79 ? 218 LYS A NZ 1 ATOM 1708 N N . SER A 1 219 ? 46.511 46.290 -2.411 1.00 5.20 ? 219 SER A N 1 ATOM 1709 C CA . SER A 1 219 ? 47.407 46.901 -1.424 1.00 5.70 ? 219 SER A CA 1 ATOM 1710 C C . SER A 1 219 ? 47.422 46.098 -0.127 1.00 6.49 ? 219 SER A C 1 ATOM 1711 O O . SER A 1 219 ? 47.802 46.657 0.897 1.00 6.74 ? 219 SER A O 1 ATOM 1712 C CB . SER A 1 219 ? 47.018 48.356 -1.153 1.00 6.52 ? 219 SER A CB 1 ATOM 1713 O OG . SER A 1 219 ? 47.104 49.094 -2.388 1.00 6.34 ? 219 SER A OG 1 ATOM 1714 N N . GLY A 1 220 ? 47.059 44.820 -0.179 1.00 6.53 ? 220 GLY A N 1 ATOM 1715 C CA . GLY A 1 220 ? 47.179 43.936 0.970 1.00 6.88 ? 220 GLY A CA 1 ATOM 1716 C C . GLY A 1 220 ? 45.946 43.880 1.864 1.00 6.52 ? 220 GLY A C 1 ATOM 1717 O O . GLY A 1 220 ? 45.939 43.117 2.844 1.00 7.83 ? 220 GLY A O 1 ATOM 1718 N N . PHE A 1 221 ? 44.904 44.686 1.596 1.00 5.98 ? 221 PHE A N 1 ATOM 1719 C CA . PHE A 1 221 ? 43.783 44.703 2.532 1.00 6.39 ? 221 PHE A CA 1 ATOM 1720 C C . PHE A 1 221 ? 42.953 43.463 2.440 1.00 6.80 ? 221 PHE A C 1 ATOM 1721 O O . PHE A 1 221 ? 42.861 42.815 1.388 1.00 7.38 ? 221 PHE A O 1 ATOM 1722 C CB . PHE A 1 221 ? 42.884 45.912 2.278 1.00 6.44 ? 221 PHE A CB 1 ATOM 1723 C CG . PHE A 1 221 ? 43.448 47.174 2.825 1.00 5.12 ? 221 PHE A CG 1 ATOM 1724 C CD1 . PHE A 1 221 ? 44.577 47.767 2.236 1.00 5.86 ? 221 PHE A CD1 1 ATOM 1725 C CD2 . PHE A 1 221 ? 42.864 47.809 3.907 1.00 5.60 ? 221 PHE A CD2 1 ATOM 1726 C CE1 . PHE A 1 221 ? 45.114 48.945 2.761 1.00 5.76 ? 221 PHE A CE1 1 ATOM 1727 C CE2 . PHE A 1 221 ? 43.403 48.941 4.443 1.00 7.75 ? 221 PHE A CE2 1 ATOM 1728 C CZ . PHE A 1 221 ? 44.496 49.535 3.861 1.00 6.44 ? 221 PHE A CZ 1 ATOM 1729 N N . LYS A 1 222 ? 42.296 43.172 3.564 1.00 6.52 ? 222 LYS A N 1 ATOM 1730 C CA . LYS A 1 222 ? 41.403 42.034 3.661 1.00 7.49 ? 222 LYS A CA 1 ATOM 1731 C C . LYS A 1 222 ? 39.991 42.433 3.999 1.00 6.81 ? 222 LYS A C 1 ATOM 1732 O O . LYS A 1 222 ? 39.101 41.636 3.781 1.00 7.31 ? 222 LYS A O 1 ATOM 1733 C CB . LYS A 1 222 ? 41.897 41.037 4.689 1.00 8.76 ? 222 LYS A CB 1 ATOM 1734 C CG . LYS A 1 222 ? 43.282 40.525 4.453 1.00 12.92 ? 222 LYS A CG 1 ATOM 1735 C CD . LYS A 1 222 ? 43.380 39.706 3.223 1.00 20.44 ? 222 LYS A CD 1 ATOM 1736 C CE . LYS A 1 222 ? 44.826 39.284 3.004 1.00 26.33 ? 222 LYS A CE 1 ATOM 1737 N NZ . LYS A 1 222 ? 44.994 38.730 1.635 1.00 30.02 ? 222 LYS A NZ 1 ATOM 1738 N N . ASN A 1 223 ? 39.751 43.640 4.519 1.00 4.62 ? 223 ASN A N 1 ATOM 1739 C CA . ASN A 1 223 ? 38.415 44.029 4.945 1.00 4.68 ? 223 ASN A CA 1 ATOM 1740 C C . ASN A 1 223 ? 38.251 45.524 4.830 1.00 5.81 ? 223 ASN A C 1 ATOM 1741 O O . ASN A 1 223 ? 39.216 46.269 4.944 1.00 6.20 ? 223 ASN A O 1 ATOM 1742 C CB . ASN A 1 223 ? 38.179 43.678 6.425 1.00 5.32 ? 223 ASN A CB 1 ATOM 1743 C CG . ASN A 1 223 ? 38.219 42.191 6.672 1.00 7.50 ? 223 ASN A CG 1 ATOM 1744 O OD1 . ASN A 1 223 ? 37.250 41.478 6.413 1.00 8.30 ? 223 ASN A OD1 1 ATOM 1745 N ND2 . ASN A 1 223 ? 39.355 41.726 7.157 1.00 8.08 ? 223 ASN A ND2 1 ATOM 1746 N N . MET A 1 224 ? 37.017 45.961 4.646 1.00 4.86 ? 224 MET A N 1 ATOM 1747 C CA . MET A 1 224 ? 36.719 47.386 4.624 1.00 6.20 ? 224 MET A CA 1 ATOM 1748 C C . MET A 1 224 ? 35.352 47.674 5.191 1.00 5.98 ? 224 MET A C 1 ATOM 1749 O O . MET A 1 224 ? 34.483 46.842 5.181 1.00 5.59 ? 224 MET A O 1 ATOM 1750 C CB . MET A 1 224 ? 36.846 47.977 3.208 1.00 7.51 ? 224 MET A CB 1 ATOM 1751 C CG . MET A 1 224 ? 35.829 47.466 2.232 1.00 8.69 ? 224 MET A CG 1 ATOM 1752 S SD . MET A 1 224 ? 36.080 48.255 0.614 1.00 10.01 ? 224 MET A SD 1 ATOM 1753 C CE . MET A 1 224 ? 35.766 49.938 1.017 1.00 12.47 ? 224 MET A CE 1 ATOM 1754 N N . LEU A 1 225 ? 35.203 48.889 5.694 1.00 5.19 ? 225 LEU A N 1 ATOM 1755 C CA . LEU A 1 225 ? 33.953 49.304 6.299 1.00 4.71 ? 225 LEU A CA 1 ATOM 1756 C C . LEU A 1 225 ? 33.524 50.613 5.624 1.00 5.58 ? 225 LEU A C 1 ATOM 1757 O O . LEU A 1 225 ? 34.327 51.509 5.413 1.00 5.62 ? 225 LEU A O 1 ATOM 1758 C CB . LEU A 1 225 ? 34.144 49.482 7.813 1.00 5.87 ? 225 LEU A CB 1 ATOM 1759 C CG . LEU A 1 225 ? 32.920 50.004 8.554 1.00 6.97 ? 225 LEU A CG 1 ATOM 1760 C CD1 . LEU A 1 225 ? 32.846 49.407 9.966 1.00 7.08 ? 225 LEU A CD1 1 ATOM 1761 C CD2 . LEU A 1 225 ? 32.924 51.542 8.582 1.00 7.12 ? 225 LEU A CD2 1 ATOM 1762 N N . ILE A 1 226 ? 32.229 50.713 5.354 1.00 5.08 ? 226 ILE A N 1 ATOM 1763 C CA . ILE A 1 226 ? 31.665 51.927 4.765 1.00 5.63 ? 226 ILE A CA 1 ATOM 1764 C C . ILE A 1 226 ? 30.386 52.304 5.509 1.00 5.20 ? 226 ILE A C 1 ATOM 1765 O O . ILE A 1 226 ? 29.801 51.462 6.233 1.00 5.91 ? 226 ILE A O 1 ATOM 1766 C CB . ILE A 1 226 ? 31.379 51.702 3.253 1.00 5.76 ? 226 ILE A CB 1 ATOM 1767 C CG1 . ILE A 1 226 ? 30.303 50.633 3.038 1.00 6.31 ? 226 ILE A CG1 1 ATOM 1768 C CG2 . ILE A 1 226 ? 32.682 51.405 2.532 1.00 6.86 ? 226 ILE A CG2 1 ATOM 1769 C CD1 . ILE A 1 226 ? 29.955 50.418 1.519 1.00 7.21 ? 226 ILE A CD1 1 ATOM 1770 N N . GLN A 1 227 ? 29.959 53.549 5.353 1.00 6.12 ? 227 GLN A N 1 ATOM 1771 C CA . GLN A 1 227 ? 28.814 54.051 6.113 1.00 6.04 ? 227 GLN A CA 1 ATOM 1772 C C . GLN A 1 227 ? 27.828 54.890 5.285 1.00 6.17 ? 227 GLN A C 1 ATOM 1773 O O . GLN A 1 227 ? 26.616 54.736 5.476 1.00 6.94 ? 227 GLN A O 1 ATOM 1774 C CB . GLN A 1 227 ? 29.319 54.901 7.273 1.00 7.38 ? 227 GLN A CB 1 ATOM 1775 C CG . GLN A 1 227 ? 28.347 55.972 7.868 1.00 10.35 ? 227 GLN A CG 1 ATOM 1776 C CD . GLN A 1 227 ? 27.041 55.450 8.414 1.00 10.38 ? 227 GLN A CD 1 ATOM 1777 O OE1 . GLN A 1 227 ? 26.944 54.306 8.820 1.00 13.53 ? 227 GLN A OE1 1 ATOM 1778 N NE2 . GLN A 1 227 ? 26.047 56.306 8.463 1.00 10.98 ? 227 GLN A NE2 1 ATOM 1779 N N . ARG A 1 228 ? 28.295 55.804 4.464 1.00 5.99 ? 228 ARG A N 1 ATOM 1780 C CA . ARG A 1 228 ? 27.351 56.726 3.876 1.00 6.44 ? 228 ARG A CA 1 ATOM 1781 C C . ARG A 1 228 ? 26.802 56.155 2.592 1.00 6.22 ? 228 ARG A C 1 ATOM 1782 O O . ARG A 1 228 ? 27.311 56.401 1.521 1.00 7.29 ? 228 ARG A O 1 ATOM 1783 C CB . ARG A 1 228 ? 27.970 58.103 3.670 1.00 7.29 ? 228 ARG A CB 1 ATOM 1784 C CG . ARG A 1 228 ? 28.066 58.945 4.921 1.00 7.22 ? 228 ARG A CG 1 ATOM 1785 C CD . ARG A 1 228 ? 28.350 60.354 4.526 1.00 9.17 ? 228 ARG A CD 1 ATOM 1786 N NE . ARG A 1 228 ? 28.672 61.257 5.625 1.00 7.67 ? 228 ARG A NE 1 ATOM 1787 C CZ . ARG A 1 228 ? 27.780 61.980 6.279 1.00 10.53 ? 228 ARG A CZ 1 ATOM 1788 N NH1 . ARG A 1 228 ? 26.494 61.818 6.032 1.00 10.17 ? 228 ARG A NH1 1 ATOM 1789 N NH2 . ARG A 1 228 ? 28.163 62.800 7.234 1.00 13.20 ? 228 ARG A NH2 1 ATOM 1790 N N . THR A 1 229 ? 25.754 55.366 2.742 1.00 6.36 ? 229 THR A N 1 ATOM 1791 C CA . THR A 1 229 ? 25.039 54.871 1.590 1.00 5.38 ? 229 THR A CA 1 ATOM 1792 C C . THR A 1 229 ? 23.581 55.270 1.734 1.00 6.29 ? 229 THR A C 1 ATOM 1793 O O . THR A 1 229 ? 23.084 55.535 2.814 1.00 7.19 ? 229 THR A O 1 ATOM 1794 C CB . THR A 1 229 ? 25.144 53.353 1.441 1.00 6.41 ? 229 THR A CB 1 ATOM 1795 O OG1 . THR A 1 229 ? 24.552 52.776 2.614 1.00 8.98 ? 229 THR A OG1 1 ATOM 1796 C CG2 . THR A 1 229 ? 26.590 52.910 1.439 1.00 6.91 ? 229 THR A CG2 1 ATOM 1797 N N . HIS A 1 230 ? 22.905 55.331 0.606 1.00 5.35 ? 230 HIS A N 1 ATOM 1798 C CA . HIS A 1 230 ? 21.508 55.772 0.615 1.00 6.20 ? 230 HIS A CA 1 ATOM 1799 C C . HIS A 1 230 ? 20.666 55.016 1.636 1.00 6.41 ? 230 HIS A C 1 ATOM 1800 O O . HIS A 1 230 ? 20.740 53.807 1.758 1.00 7.56 ? 230 HIS A O 1 ATOM 1801 C CB . HIS A 1 230 ? 20.966 55.525 -0.792 1.00 6.14 ? 230 HIS A CB 1 ATOM 1802 C CG . HIS A 1 230 ? 19.674 56.220 -1.116 1.00 7.64 ? 230 HIS A CG 1 ATOM 1803 N ND1 . HIS A 1 230 ? 18.491 55.936 -0.463 1.00 7.41 ? 230 HIS A ND1 1 ATOM 1804 C CD2 . HIS A 1 230 ? 19.377 57.145 -2.065 1.00 9.24 ? 230 HIS A CD2 1 ATOM 1805 C CE1 . HIS A 1 230 ? 17.530 56.695 -0.965 1.00 7.57 ? 230 HIS A CE1 1 ATOM 1806 N NE2 . HIS A 1 230 ? 18.036 57.425 -1.944 1.00 7.64 ? 230 HIS A NE2 1 ATOM 1807 N N . TYR A 1 231 ? 19.833 55.760 2.359 1.00 7.39 ? 231 TYR A N 1 ATOM 1808 C CA . TYR A 1 231 ? 19.033 55.128 3.392 1.00 7.05 ? 231 TYR A CA 1 ATOM 1809 C C . TYR A 1 231 ? 18.135 54.019 2.858 1.00 7.39 ? 231 TYR A C 1 ATOM 1810 O O . TYR A 1 231 ? 17.859 53.048 3.570 1.00 7.70 ? 231 TYR A O 1 ATOM 1811 C CB . TYR A 1 231 ? 18.213 56.156 4.157 1.00 6.97 ? 231 TYR A CB 1 ATOM 1812 C CG . TYR A 1 231 ? 17.211 56.934 3.319 1.00 8.14 ? 231 TYR A CG 1 ATOM 1813 C CD1 . TYR A 1 231 ? 15.897 56.464 3.135 1.00 7.76 ? 231 TYR A CD1 1 ATOM 1814 C CD2 . TYR A 1 231 ? 17.557 58.142 2.735 1.00 6.70 ? 231 TYR A CD2 1 ATOM 1815 C CE1 . TYR A 1 231 ? 14.975 57.179 2.364 1.00 9.67 ? 231 TYR A CE1 1 ATOM 1816 C CE2 . TYR A 1 231 ? 16.644 58.872 1.980 1.00 7.35 ? 231 TYR A CE2 1 ATOM 1817 C CZ . TYR A 1 231 ? 15.354 58.372 1.806 1.00 7.55 ? 231 TYR A CZ 1 ATOM 1818 O OH . TYR A 1 231 ? 14.441 59.093 1.053 1.00 10.25 ? 231 TYR A OH 1 ATOM 1819 N N . SER A 1 232 ? 17.699 54.120 1.619 1.00 7.12 ? 232 SER A N 1 ATOM 1820 C CA . SER A 1 232 ? 16.863 53.042 1.054 1.00 8.34 ? 232 SER A CA 1 ATOM 1821 C C . SER A 1 232 ? 17.667 51.787 0.788 1.00 8.51 ? 232 SER A C 1 ATOM 1822 O O . SER A 1 232 ? 17.154 50.660 0.887 1.00 8.77 ? 232 SER A O 1 ATOM 1823 C CB . SER A 1 232 ? 16.207 53.463 -0.254 1.00 9.11 ? 232 SER A CB 1 ATOM 1824 O OG . SER A 1 232 ? 15.331 54.532 -0.072 1.00 11.42 ? 232 SER A OG 1 ATOM 1825 N N . VAL A 1 233 ? 18.931 51.960 0.395 1.00 7.88 ? 233 VAL A N 1 ATOM 1826 C CA . VAL A 1 233 ? 19.835 50.842 0.197 1.00 7.86 ? 233 VAL A CA 1 ATOM 1827 C C . VAL A 1 233 ? 20.119 50.133 1.535 1.00 7.95 ? 233 VAL A C 1 ATOM 1828 O O . VAL A 1 233 ? 20.127 48.901 1.597 1.00 8.23 ? 233 VAL A O 1 ATOM 1829 C CB . VAL A 1 233 ? 21.155 51.331 -0.469 1.00 7.99 ? 233 VAL A CB 1 ATOM 1830 C CG1 . VAL A 1 233 ? 22.158 50.211 -0.462 1.00 8.05 ? 233 VAL A CG1 1 ATOM 1831 C CG2 . VAL A 1 233 ? 20.838 51.702 -1.910 1.00 8.31 ? 233 VAL A CG2 1 ATOM 1832 N N . LYS A 1 234 ? 20.409 50.910 2.576 1.00 6.76 ? 234 LYS A N 1 ATOM 1833 C CA . LYS A 1 234 ? 20.618 50.307 3.906 1.00 7.27 ? 234 LYS A CA 1 ATOM 1834 C C . LYS A 1 234 ? 19.390 49.467 4.263 1.00 7.31 ? 234 LYS A C 1 ATOM 1835 O O . LYS A 1 234 ? 19.545 48.364 4.742 1.00 7.96 ? 234 LYS A O 1 ATOM 1836 C CB . LYS A 1 234 ? 20.826 51.396 4.951 1.00 7.26 ? 234 LYS A CB 1 ATOM 1837 C CG . LYS A 1 234 ? 22.195 52.077 4.875 1.00 7.93 ? 234 LYS A CG 1 ATOM 1838 C CD . LYS A 1 234 ? 22.238 53.314 5.728 1.00 8.19 ? 234 LYS A CD 1 ATOM 1839 C CE . LYS A 1 234 ? 23.631 54.031 5.685 1.00 8.03 ? 234 LYS A CE 1 ATOM 1840 N NZ . LYS A 1 234 ? 24.513 53.520 6.783 1.00 8.06 ? 234 LYS A NZ 1 ATOM 1841 N N . LYS A 1 235 ? 18.181 50.013 4.088 1.00 8.09 ? 235 LYS A N 1 ATOM 1842 C CA . LYS A 1 235 ? 16.963 49.253 4.469 1.00 8.35 ? 235 LYS A CA 1 ATOM 1843 C C . LYS A 1 235 ? 16.861 47.973 3.670 1.00 9.11 ? 235 LYS A C 1 ATOM 1844 O O . LYS A 1 235 ? 16.609 46.909 4.240 1.00 9.48 ? 235 LYS A O 1 ATOM 1845 C CB . LYS A 1 235 ? 15.726 50.110 4.287 1.00 9.00 ? 235 LYS A CB 1 ATOM 1846 C CG . LYS A 1 235 ? 14.425 49.394 4.745 1.00 10.73 ? 235 LYS A CG 1 ATOM 1847 C CD . LYS A 1 235 ? 13.282 50.390 4.706 1.00 12.87 ? 235 LYS A CD 1 ATOM 1848 C CE . LYS A 1 235 ? 11.988 49.770 5.235 1.00 16.28 ? 235 LYS A CE 1 ATOM 1849 N NZ . LYS A 1 235 ? 10.848 50.658 4.820 1.00 20.90 ? 235 LYS A NZ 1 ATOM 1850 N N . GLU A 1 236 ? 17.097 48.051 2.365 1.00 9.11 ? 236 GLU A N 1 ATOM 1851 C CA . GLU A 1 236 ? 16.967 46.893 1.482 1.00 9.92 ? 236 GLU A CA 1 ATOM 1852 C C . GLU A 1 236 ? 17.982 45.807 1.836 1.00 10.36 ? 236 GLU A C 1 ATOM 1853 O O . GLU A 1 236 ? 17.663 44.613 1.942 1.00 10.46 ? 236 GLU A O 1 ATOM 1854 C CB . GLU A 1 236 ? 17.119 47.354 0.022 1.00 12.39 ? 236 GLU A CB 1 ATOM 1855 C CG . GLU A 1 236 ? 16.873 46.298 -1.048 1.00 17.26 ? 236 GLU A CG 1 ATOM 1856 C CD . GLU A 1 236 ? 15.398 45.901 -1.181 1.00 23.05 ? 236 GLU A CD 1 ATOM 1857 O OE1 . GLU A 1 236 ? 14.495 46.674 -0.767 1.00 27.28 ? 236 GLU A OE1 1 ATOM 1858 O OE2 . GLU A 1 236 ? 15.138 44.806 -1.714 1.00 29.00 ? 236 GLU A OE2 1 ATOM 1859 N N . LEU A 1 237 ? 19.239 46.191 1.987 1.00 9.10 ? 237 LEU A N 1 ATOM 1860 C CA . LEU A 1 237 ? 20.263 45.219 2.319 1.00 8.80 ? 237 LEU A CA 1 ATOM 1861 C C . LEU A 1 237 ? 20.050 44.684 3.730 1.00 8.58 ? 237 LEU A C 1 ATOM 1862 O O . LEU A 1 237 ? 20.299 43.509 3.991 1.00 9.58 ? 237 LEU A O 1 ATOM 1863 C CB . LEU A 1 237 ? 21.669 45.804 2.148 1.00 7.90 ? 237 LEU A CB 1 ATOM 1864 C CG . LEU A 1 237 ? 22.008 46.260 0.728 1.00 8.21 ? 237 LEU A CG 1 ATOM 1865 C CD1 . LEU A 1 237 ? 23.422 46.838 0.753 1.00 10.73 ? 237 LEU A CD1 1 ATOM 1866 C CD2 . LEU A 1 237 ? 21.951 45.141 -0.318 1.00 10.85 ? 237 LEU A CD2 1 ATOM 1867 N N . ALA A 1 238 ? 19.623 45.529 4.659 1.00 8.27 ? 238 ALA A N 1 ATOM 1868 C CA . ALA A 1 238 ? 19.438 45.054 6.041 1.00 8.53 ? 238 ALA A CA 1 ATOM 1869 C C . ALA A 1 238 ? 18.350 43.974 6.098 1.00 9.77 ? 238 ALA A C 1 ATOM 1870 O O . ALA A 1 238 ? 18.503 42.970 6.816 1.00 9.70 ? 238 ALA A O 1 ATOM 1871 C CB . ALA A 1 238 ? 19.085 46.224 6.946 1.00 8.33 ? 238 ALA A CB 1 ATOM 1872 N N . GLN A 1 239 ? 17.285 44.176 5.335 1.00 10.25 ? 239 GLN A N 1 ATOM 1873 C CA . GLN A 1 239 ? 16.184 43.191 5.313 1.00 12.40 ? 239 GLN A CA 1 ATOM 1874 C C . GLN A 1 239 ? 16.652 41.813 4.875 1.00 12.66 ? 239 GLN A C 1 ATOM 1875 O O . GLN A 1 239 ? 16.086 40.817 5.291 1.00 14.47 ? 239 GLN A O 1 ATOM 1876 C CB . GLN A 1 239 ? 15.041 43.703 4.447 1.00 14.06 ? 239 GLN A CB 1 ATOM 1877 C CG . GLN A 1 239 ? 14.229 44.748 5.177 1.00 18.37 ? 239 GLN A CG 1 ATOM 1878 C CD . GLN A 1 239 ? 13.235 45.497 4.306 1.00 23.25 ? 239 GLN A CD 1 ATOM 1879 O OE1 . GLN A 1 239 ? 13.364 45.551 3.083 1.00 25.82 ? 239 GLN A OE1 1 ATOM 1880 N NE2 . GLN A 1 239 ? 12.246 46.106 4.953 1.00 25.94 ? 239 GLN A NE2 1 ATOM 1881 N N . GLN A 1 240 ? 17.696 41.756 4.063 1.00 11.42 ? 240 GLN A N 1 ATOM 1882 C CA . GLN A 1 240 ? 18.195 40.514 3.505 1.00 10.74 ? 240 GLN A CA 1 ATOM 1883 C C . GLN A 1 240 ? 19.500 40.055 4.168 1.00 9.58 ? 240 GLN A C 1 ATOM 1884 O O . GLN A 1 240 ? 20.143 39.105 3.718 1.00 9.52 ? 240 GLN A O 1 ATOM 1885 C CB . GLN A 1 240 ? 18.441 40.673 1.991 1.00 12.45 ? 240 GLN A CB 1 ATOM 1886 C CG . GLN A 1 240 ? 17.231 41.168 1.197 1.00 15.46 ? 240 GLN A CG 1 ATOM 1887 C CD . GLN A 1 240 ? 16.072 40.200 1.264 1.00 19.60 ? 240 GLN A CD 1 ATOM 1888 O OE1 . GLN A 1 240 ? 16.270 38.981 1.362 1.00 23.01 ? 240 GLN A OE1 1 ATOM 1889 N NE2 . GLN A 1 240 ? 14.849 40.737 1.231 1.00 24.84 ? 240 GLN A NE2 1 ATOM 1890 N N . ARG A 1 241 ? 19.883 40.769 5.240 1.00 9.14 ? 241 ARG A N 1 ATOM 1891 C CA A ARG A 1 241 ? 21.188 40.567 5.878 0.50 7.98 ? 241 ARG A CA 1 ATOM 1892 C CA B ARG A 1 241 ? 21.194 40.561 5.871 0.50 8.11 ? 241 ARG A CA 1 ATOM 1893 C C . ARG A 1 241 ? 22.306 40.529 4.845 1.00 7.67 ? 241 ARG A C 1 ATOM 1894 O O . ARG A 1 241 ? 23.167 39.626 4.839 1.00 7.67 ? 241 ARG A O 1 ATOM 1895 C CB A ARG A 1 241 ? 21.189 39.310 6.756 0.50 8.69 ? 241 ARG A CB 1 ATOM 1896 C CB B ARG A 1 241 ? 21.229 39.291 6.730 0.50 8.79 ? 241 ARG A CB 1 ATOM 1897 C CG A ARG A 1 241 ? 19.998 39.281 7.706 0.50 9.17 ? 241 ARG A CG 1 ATOM 1898 C CG B ARG A 1 241 ? 20.420 39.447 7.986 0.50 10.19 ? 241 ARG A CG 1 ATOM 1899 C CD A ARG A 1 241 ? 20.080 38.202 8.751 0.50 11.33 ? 241 ARG A CD 1 ATOM 1900 C CD B ARG A 1 241 ? 20.351 38.200 8.828 0.50 12.78 ? 241 ARG A CD 1 ATOM 1901 N NE A ARG A 1 241 ? 20.233 36.890 8.135 0.50 11.43 ? 241 ARG A NE 1 ATOM 1902 N NE B ARG A 1 241 ? 19.323 38.348 9.854 0.50 15.45 ? 241 ARG A NE 1 ATOM 1903 C CZ A ARG A 1 241 ? 20.708 35.827 8.765 0.50 11.97 ? 241 ARG A CZ 1 ATOM 1904 C CZ B ARG A 1 241 ? 18.672 37.344 10.424 0.50 18.79 ? 241 ARG A CZ 1 ATOM 1905 N NH1 A ARG A 1 241 ? 21.064 35.918 10.030 0.50 12.74 ? 241 ARG A NH1 1 ATOM 1906 N NH1 B ARG A 1 241 ? 18.926 36.090 10.069 0.50 19.84 ? 241 ARG A NH1 1 ATOM 1907 N NH2 A ARG A 1 241 ? 20.825 34.669 8.124 0.50 12.48 ? 241 ARG A NH2 1 ATOM 1908 N NH2 B ARG A 1 241 ? 17.765 37.599 11.358 0.50 18.06 ? 241 ARG A NH2 1 ATOM 1909 N N . GLN A 1 242 ? 22.300 41.563 3.989 1.00 6.58 ? 242 GLN A N 1 ATOM 1910 C CA . GLN A 1 242 ? 23.336 41.697 2.957 1.00 7.40 ? 242 GLN A CA 1 ATOM 1911 C C . GLN A 1 242 ? 24.173 42.959 3.193 1.00 6.98 ? 242 GLN A C 1 ATOM 1912 O O . GLN A 1 242 ? 24.727 43.497 2.236 1.00 8.45 ? 242 GLN A O 1 ATOM 1913 C CB . GLN A 1 242 ? 22.718 41.732 1.573 1.00 8.05 ? 242 GLN A CB 1 ATOM 1914 C CG . GLN A 1 242 ? 22.060 40.434 1.171 1.00 9.04 ? 242 GLN A CG 1 ATOM 1915 C CD . GLN A 1 242 ? 21.222 40.549 -0.096 1.00 9.65 ? 242 GLN A CD 1 ATOM 1916 O OE1 . GLN A 1 242 ? 20.641 41.601 -0.363 1.00 12.04 ? 242 GLN A OE1 1 ATOM 1917 N NE2 . GLN A 1 242 ? 21.174 39.468 -0.879 1.00 11.80 ? 242 GLN A NE2 1 ATOM 1918 N N . LEU A 1 243 ? 24.279 43.382 4.457 1.00 6.38 ? 243 LEU A N 1 ATOM 1919 C CA . LEU A 1 243 ? 25.132 44.515 4.799 1.00 5.61 ? 243 LEU A CA 1 ATOM 1920 C C . LEU A 1 243 ? 26.598 44.148 4.870 1.00 6.33 ? 243 LEU A C 1 ATOM 1921 O O . LEU A 1 243 ? 27.452 45.048 4.883 1.00 7.48 ? 243 LEU A O 1 ATOM 1922 C CB . LEU A 1 243 ? 24.694 45.097 6.137 1.00 7.13 ? 243 LEU A CB 1 ATOM 1923 C CG . LEU A 1 243 ? 23.301 45.726 6.132 1.00 7.65 ? 243 LEU A CG 1 ATOM 1924 C CD1 . LEU A 1 243 ? 22.807 45.852 7.559 1.00 10.54 ? 243 LEU A CD1 1 ATOM 1925 C CD2 . LEU A 1 243 ? 23.315 47.110 5.463 1.00 9.23 ? 243 LEU A CD2 1 ATOM 1926 N N . GLU A 1 244 ? 26.933 42.870 4.949 1.00 5.96 ? 244 GLU A N 1 ATOM 1927 C CA . GLU A 1 244 ? 28.314 42.422 4.807 1.00 6.19 ? 244 GLU A CA 1 ATOM 1928 C C . GLU A 1 244 ? 28.350 41.611 3.541 1.00 6.21 ? 244 GLU A C 1 ATOM 1929 O O . GLU A 1 244 ? 27.510 40.700 3.327 1.00 7.30 ? 244 GLU A O 1 ATOM 1930 C CB . GLU A 1 244 ? 28.779 41.599 6.013 1.00 6.41 ? 244 GLU A CB 1 ATOM 1931 C CG . GLU A 1 244 ? 29.010 42.496 7.224 1.00 7.76 ? 244 GLU A CG 1 ATOM 1932 C CD . GLU A 1 244 ? 29.361 41.789 8.524 1.00 8.94 ? 244 GLU A CD 1 ATOM 1933 O OE1 . GLU A 1 244 ? 28.784 40.694 8.807 1.00 9.33 ? 244 GLU A OE1 1 ATOM 1934 O OE2 . GLU A 1 244 ? 30.216 42.353 9.268 1.00 8.36 ? 244 GLU A OE2 1 ATOM 1935 N N . PHE A 1 245 ? 29.323 41.903 2.689 1.00 5.50 ? 245 PHE A N 1 ATOM 1936 C CA . PHE A 1 245 ? 29.322 41.315 1.346 1.00 5.43 ? 245 PHE A CA 1 ATOM 1937 C C . PHE A 1 245 ? 30.725 41.262 0.807 1.00 5.70 ? 245 PHE A C 1 ATOM 1938 O O . PHE A 1 245 ? 31.596 42.017 1.230 1.00 6.12 ? 245 PHE A O 1 ATOM 1939 C CB . PHE A 1 245 ? 28.406 42.077 0.355 1.00 6.69 ? 245 PHE A CB 1 ATOM 1940 C CG . PHE A 1 245 ? 28.545 43.570 0.408 1.00 5.92 ? 245 PHE A CG 1 ATOM 1941 C CD1 . PHE A 1 245 ? 29.486 44.226 -0.383 1.00 5.66 ? 245 PHE A CD1 1 ATOM 1942 C CD2 . PHE A 1 245 ? 27.755 44.328 1.254 1.00 6.98 ? 245 PHE A CD2 1 ATOM 1943 C CE1 . PHE A 1 245 ? 29.609 45.609 -0.375 1.00 4.92 ? 245 PHE A CE1 1 ATOM 1944 C CE2 . PHE A 1 245 ? 27.894 45.726 1.292 1.00 6.79 ? 245 PHE A CE2 1 ATOM 1945 C CZ . PHE A 1 245 ? 28.821 46.352 0.468 1.00 5.65 ? 245 PHE A CZ 1 ATOM 1946 N N . LEU A 1 246 ? 30.923 40.420 -0.191 1.00 5.39 ? 246 LEU A N 1 ATOM 1947 C CA . LEU A 1 246 ? 32.183 40.375 -0.910 1.00 6.03 ? 246 LEU A CA 1 ATOM 1948 C C . LEU A 1 246 ? 32.072 41.290 -2.130 1.00 5.97 ? 246 LEU A C 1 ATOM 1949 O O . LEU A 1 246 ? 31.370 40.984 -3.113 1.00 5.58 ? 246 LEU A O 1 ATOM 1950 C CB . LEU A 1 246 ? 32.544 38.931 -1.305 1.00 6.86 ? 246 LEU A CB 1 ATOM 1951 C CG . LEU A 1 246 ? 32.882 38.024 -0.109 1.00 10.13 ? 246 LEU A CG 1 ATOM 1952 C CD1 . LEU A 1 246 ? 32.725 36.562 -0.570 1.00 12.48 ? 246 LEU A CD1 1 ATOM 1953 C CD2 . LEU A 1 246 ? 34.299 38.348 0.384 1.00 13.26 ? 246 LEU A CD2 1 ATOM 1954 N N . TRP A 1 247 ? 32.719 42.438 -2.032 1.00 5.19 ? 247 TRP A N 1 ATOM 1955 C CA . TRP A 1 247 ? 32.534 43.469 -3.051 1.00 4.71 ? 247 TRP A CA 1 ATOM 1956 C C . TRP A 1 247 ? 33.544 43.276 -4.141 1.00 4.84 ? 247 TRP A C 1 ATOM 1957 O O . TRP A 1 247 ? 34.740 43.440 -3.904 1.00 4.96 ? 247 TRP A O 1 ATOM 1958 C CB . TRP A 1 247 ? 32.739 44.832 -2.390 1.00 5.01 ? 247 TRP A CB 1 ATOM 1959 C CG . TRP A 1 247 ? 32.252 46.017 -3.216 1.00 4.63 ? 247 TRP A CG 1 ATOM 1960 C CD1 . TRP A 1 247 ? 31.722 46.003 -4.476 1.00 5.20 ? 247 TRP A CD1 1 ATOM 1961 C CD2 . TRP A 1 247 ? 32.263 47.386 -2.800 1.00 4.42 ? 247 TRP A CD2 1 ATOM 1962 N NE1 . TRP A 1 247 ? 31.411 47.290 -4.883 1.00 4.72 ? 247 TRP A NE1 1 ATOM 1963 C CE2 . TRP A 1 247 ? 31.707 48.152 -3.844 1.00 4.43 ? 247 TRP A CE2 1 ATOM 1964 C CE3 . TRP A 1 247 ? 32.672 48.036 -1.632 1.00 4.85 ? 247 TRP A CE3 1 ATOM 1965 C CZ2 . TRP A 1 247 ? 31.607 49.558 -3.762 1.00 5.55 ? 247 TRP A CZ2 1 ATOM 1966 C CZ3 . TRP A 1 247 ? 32.534 49.415 -1.548 1.00 4.48 ? 247 TRP A CZ3 1 ATOM 1967 C CH2 . TRP A 1 247 ? 32.033 50.155 -2.599 1.00 5.78 ? 247 TRP A CH2 1 ATOM 1968 N N . ARG A 1 248 ? 33.049 42.870 -5.334 1.00 4.87 ? 248 ARG A N 1 ATOM 1969 C CA . ARG A 1 248 ? 33.921 42.677 -6.480 1.00 5.05 ? 248 ARG A CA 1 ATOM 1970 C C . ARG A 1 248 ? 33.668 43.765 -7.521 1.00 5.42 ? 248 ARG A C 1 ATOM 1971 O O . ARG A 1 248 ? 32.625 44.436 -7.500 1.00 5.88 ? 248 ARG A O 1 ATOM 1972 C CB . ARG A 1 248 ? 33.696 41.301 -7.129 1.00 5.93 ? 248 ARG A CB 1 ATOM 1973 C CG . ARG A 1 248 ? 32.356 41.146 -7.762 1.00 6.79 ? 248 ARG A CG 1 ATOM 1974 C CD . ARG A 1 248 ? 32.280 39.877 -8.629 1.00 9.02 ? 248 ARG A CD 1 ATOM 1975 N NE . ARG A 1 248 ? 32.317 38.702 -7.751 1.00 8.13 ? 248 ARG A NE 1 ATOM 1976 C CZ . ARG A 1 248 ? 32.231 37.451 -8.197 1.00 12.56 ? 248 ARG A CZ 1 ATOM 1977 N NH1 . ARG A 1 248 ? 32.111 37.214 -9.504 1.00 13.18 ? 248 ARG A NH1 1 ATOM 1978 N NH2 . ARG A 1 248 ? 32.236 36.435 -7.338 1.00 12.59 ? 248 ARG A NH2 1 ATOM 1979 N N . GLN A 1 249 ? 34.633 43.890 -8.440 1.00 5.49 ? 249 GLN A N 1 ATOM 1980 C CA . GLN A 1 249 ? 34.483 44.854 -9.528 1.00 5.70 ? 249 GLN A CA 1 ATOM 1981 C C . GLN A 1 249 ? 33.371 44.428 -10.492 1.00 6.93 ? 249 GLN A C 1 ATOM 1982 O O . GLN A 1 249 ? 33.092 43.235 -10.651 1.00 7.41 ? 249 GLN A O 1 ATOM 1983 C CB . GLN A 1 249 ? 35.821 45.028 -10.232 1.00 6.67 ? 249 GLN A CB 1 ATOM 1984 C CG . GLN A 1 249 ? 36.900 45.558 -9.291 1.00 6.87 ? 249 GLN A CG 1 ATOM 1985 C CD . GLN A 1 249 ? 36.494 46.876 -8.645 1.00 7.02 ? 249 GLN A CD 1 ATOM 1986 O OE1 . GLN A 1 249 ? 36.164 47.856 -9.341 1.00 6.86 ? 249 GLN A OE1 1 ATOM 1987 N NE2 . GLN A 1 249 ? 36.479 46.908 -7.322 1.00 6.30 ? 249 GLN A NE2 1 ATOM 1988 N N . ILE A 1 250 ? 32.763 45.409 -11.155 1.00 6.99 ? 250 ILE A N 1 ATOM 1989 C CA . ILE A 1 250 ? 31.605 45.132 -11.993 1.00 7.31 ? 250 ILE A CA 1 ATOM 1990 C C . ILE A 1 250 ? 31.888 44.189 -13.152 1.00 8.23 ? 250 ILE A C 1 ATOM 1991 O O . ILE A 1 250 ? 30.984 43.543 -13.621 1.00 8.81 ? 250 ILE A O 1 ATOM 1992 C CB . ILE A 1 250 ? 30.907 46.433 -12.498 1.00 8.24 ? 250 ILE A CB 1 ATOM 1993 C CG1 . ILE A 1 250 ? 31.863 47.329 -13.262 1.00 9.03 ? 250 ILE A CG1 1 ATOM 1994 C CG2 . ILE A 1 250 ? 30.254 47.209 -11.343 1.00 9.34 ? 250 ILE A CG2 1 ATOM 1995 C CD1 . ILE A 1 250 ? 31.257 48.659 -13.755 1.00 11.08 ? 250 ILE A CD1 1 ATOM 1996 N N . TRP A 1 251 ? 33.136 44.143 -13.596 1.00 8.89 ? 251 TRP A N 1 ATOM 1997 C CA . TRP A 1 251 ? 33.462 43.290 -14.750 1.00 10.62 ? 251 TRP A CA 1 ATOM 1998 C C . TRP A 1 251 ? 34.046 41.938 -14.334 1.00 12.64 ? 251 TRP A C 1 ATOM 1999 O O . TRP A 1 251 ? 34.374 41.096 -15.181 1.00 12.54 ? 251 TRP A O 1 ATOM 2000 C CB . TRP A 1 251 ? 34.490 43.999 -15.618 1.00 10.82 ? 251 TRP A CB 1 ATOM 2001 C CG . TRP A 1 251 ? 35.723 44.147 -14.890 1.00 13.25 ? 251 TRP A CG 1 ATOM 2002 C CD1 . TRP A 1 251 ? 36.691 43.190 -14.703 1.00 16.12 ? 251 TRP A CD1 1 ATOM 2003 C CD2 . TRP A 1 251 ? 36.144 45.295 -14.197 1.00 11.98 ? 251 TRP A CD2 1 ATOM 2004 N NE1 . TRP A 1 251 ? 37.692 43.694 -13.924 1.00 15.09 ? 251 TRP A NE1 1 ATOM 2005 C CE2 . TRP A 1 251 ? 37.394 44.995 -13.609 1.00 12.46 ? 251 TRP A CE2 1 ATOM 2006 C CE3 . TRP A 1 251 ? 35.596 46.557 -13.997 1.00 11.41 ? 251 TRP A CE3 1 ATOM 2007 C CZ2 . TRP A 1 251 ? 38.085 45.903 -12.834 1.00 12.83 ? 251 TRP A CZ2 1 ATOM 2008 C CZ3 . TRP A 1 251 ? 36.278 47.459 -13.232 1.00 13.37 ? 251 TRP A CZ3 1 ATOM 2009 C CH2 . TRP A 1 251 ? 37.522 47.147 -12.680 1.00 13.93 ? 251 TRP A CH2 1 ATOM 2010 N N . ASP A 1 252 ? 34.227 41.719 -13.041 1.00 11.06 ? 252 ASP A N 1 ATOM 2011 C CA . ASP A 1 252 ? 34.991 40.577 -12.563 1.00 11.99 ? 252 ASP A CA 1 ATOM 2012 C C . ASP A 1 252 ? 34.153 39.314 -12.452 1.00 12.77 ? 252 ASP A C 1 ATOM 2013 O O . ASP A 1 252 ? 33.370 39.140 -11.525 1.00 12.05 ? 252 ASP A O 1 ATOM 2014 C CB . ASP A 1 252 ? 35.611 40.952 -11.215 1.00 10.76 ? 252 ASP A CB 1 ATOM 2015 C CG . ASP A 1 252 ? 36.351 39.821 -10.568 1.00 14.78 ? 252 ASP A CG 1 ATOM 2016 O OD1 . ASP A 1 252 ? 36.619 38.779 -11.215 1.00 16.51 ? 252 ASP A OD1 1 ATOM 2017 O OD2 . ASP A 1 252 ? 36.694 39.913 -9.377 1.00 13.03 ? 252 ASP A OD2 1 ATOM 2018 N N A ASN A 1 253 ? 34.344 38.434 -13.428 0.50 13.62 ? 253 ASN A N 1 ATOM 2019 N N B ASN A 1 253 ? 34.297 38.413 -13.426 0.50 13.75 ? 253 ASN A N 1 ATOM 2020 C CA A ASN A 1 253 ? 33.568 37.225 -13.499 0.50 14.51 ? 253 ASN A CA 1 ATOM 2021 C CA B ASN A 1 253 ? 33.504 37.189 -13.423 0.50 14.79 ? 253 ASN A CA 1 ATOM 2022 C C A ASN A 1 253 ? 33.933 36.187 -12.446 0.50 14.82 ? 253 ASN A C 1 ATOM 2023 C C B ASN A 1 253 ? 33.924 36.171 -12.391 0.50 15.03 ? 253 ASN A C 1 ATOM 2024 O O A ASN A 1 253 ? 33.049 35.516 -11.906 0.50 15.46 ? 253 ASN A O 1 ATOM 2025 O O B ASN A 1 253 ? 33.072 35.489 -11.815 0.50 15.85 ? 253 ASN A O 1 ATOM 2026 C CB A ASN A 1 253 ? 33.708 36.613 -14.883 0.50 14.60 ? 253 ASN A CB 1 ATOM 2027 C CB B ASN A 1 253 ? 33.518 36.535 -14.796 0.50 15.17 ? 253 ASN A CB 1 ATOM 2028 C CG A ASN A 1 253 ? 32.774 35.471 -15.080 0.50 15.19 ? 253 ASN A CG 1 ATOM 2029 C CG B ASN A 1 253 ? 32.569 37.195 -15.732 0.50 15.91 ? 253 ASN A CG 1 ATOM 2030 O OD1 A ASN A 1 253 ? 31.582 35.567 -14.784 0.50 13.79 ? 253 ASN A OD1 1 ATOM 2031 O OD1 B ASN A 1 253 ? 31.368 36.907 -15.724 0.50 18.73 ? 253 ASN A OD1 1 ATOM 2032 N ND2 A ASN A 1 253 ? 33.311 34.357 -15.558 0.50 15.61 ? 253 ASN A ND2 1 ATOM 2033 N ND2 B ASN A 1 253 ? 33.091 38.096 -16.552 0.50 17.97 ? 253 ASN A ND2 1 ATOM 2034 N N . LYS A 1 254 ? 35.227 36.084 -12.169 1.00 16.26 ? 254 LYS A N 1 ATOM 2035 C CA . LYS A 1 254 ? 35.783 35.049 -11.315 1.00 17.37 ? 254 LYS A CA 1 ATOM 2036 C C . LYS A 1 254 ? 35.674 35.433 -9.854 1.00 17.63 ? 254 LYS A C 1 ATOM 2037 O O . LYS A 1 254 ? 35.355 34.590 -9.017 1.00 19.13 ? 254 LYS A O 1 ATOM 2038 C CB . LYS A 1 254 ? 37.234 34.789 -11.715 1.00 18.87 ? 254 LYS A CB 1 ATOM 2039 C CG . LYS A 1 254 ? 37.922 33.668 -10.948 1.00 23.33 ? 254 LYS A CG 1 ATOM 2040 C CD . LYS A 1 254 ? 39.132 33.157 -11.739 1.00 27.67 ? 254 LYS A CD 1 ATOM 2041 C CE . LYS A 1 254 ? 40.222 32.574 -10.832 1.00 30.10 ? 254 LYS A CE 1 ATOM 2042 N NZ . LYS A 1 254 ? 39.732 31.952 -9.554 1.00 31.03 ? 254 LYS A NZ 1 ATOM 2043 N N . GLY A 1 255 ? 35.900 36.705 -9.554 1.00 16.78 ? 255 GLY A N 1 ATOM 2044 C CA . GLY A 1 255 ? 35.816 37.145 -8.169 1.00 15.81 ? 255 GLY A CA 1 ATOM 2045 C C . GLY A 1 255 ? 37.146 37.448 -7.511 1.00 15.29 ? 255 GLY A C 1 ATOM 2046 O O . GLY A 1 255 ? 37.161 37.750 -6.330 1.00 14.52 ? 255 GLY A O 1 ATOM 2047 N N . ASP A 1 256 ? 38.248 37.453 -8.258 1.00 15.07 ? 256 ASP A N 1 ATOM 2048 C CA . ASP A 1 256 ? 39.557 37.670 -7.626 1.00 16.52 ? 256 ASP A CA 1 ATOM 2049 C C . ASP A 1 256 ? 39.756 39.079 -7.065 1.00 14.59 ? 256 ASP A C 1 ATOM 2050 O O . ASP A 1 256 ? 40.639 39.301 -6.232 1.00 14.76 ? 256 ASP A O 1 ATOM 2051 C CB . ASP A 1 256 ? 40.719 37.356 -8.563 1.00 19.06 ? 256 ASP A CB 1 ATOM 2052 C CG . ASP A 1 256 ? 40.742 35.914 -9.010 1.00 25.11 ? 256 ASP A CG 1 ATOM 2053 O OD1 . ASP A 1 256 ? 40.225 35.031 -8.272 1.00 30.83 ? 256 ASP A OD1 1 ATOM 2054 O OD2 . ASP A 1 256 ? 41.282 35.585 -10.093 1.00 31.54 ? 256 ASP A OD2 1 ATOM 2055 N N . THR A 1 257 ? 38.911 40.011 -7.494 1.00 12.21 ? 257 THR A N 1 ATOM 2056 C CA . THR A 1 257 ? 39.012 41.371 -6.952 1.00 11.46 ? 257 THR A CA 1 ATOM 2057 C C . THR A 1 257 ? 38.266 41.559 -5.628 1.00 11.07 ? 257 THR A C 1 ATOM 2058 O O . THR A 1 257 ? 38.336 42.639 -5.035 1.00 11.40 ? 257 THR A O 1 ATOM 2059 C CB . THR A 1 257 ? 38.475 42.431 -7.940 1.00 11.84 ? 257 THR A CB 1 ATOM 2060 O OG1 . THR A 1 257 ? 37.069 42.205 -8.174 1.00 9.40 ? 257 THR A OG1 1 ATOM 2061 C CG2 . THR A 1 257 ? 39.190 42.316 -9.301 1.00 13.45 ? 257 THR A CG2 1 ATOM 2062 N N . ALA A 1 258 ? 37.525 40.535 -5.201 1.00 10.11 ? 258 ALA A N 1 ATOM 2063 C CA . ALA A 1 258 ? 36.590 40.699 -4.079 1.00 8.30 ? 258 ALA A CA 1 ATOM 2064 C C . ALA A 1 258 ? 37.261 41.101 -2.764 1.00 8.18 ? 258 ALA A C 1 ATOM 2065 O O . ALA A 1 258 ? 38.346 40.609 -2.409 1.00 9.86 ? 258 ALA A O 1 ATOM 2066 C CB . ALA A 1 258 ? 35.791 39.459 -3.850 1.00 9.56 ? 258 ALA A CB 1 ATOM 2067 N N . LEU A 1 259 ? 36.612 42.025 -2.075 1.00 6.31 ? 259 LEU A N 1 ATOM 2068 C CA . LEU A 1 259 ? 37.074 42.465 -0.756 1.00 6.10 ? 259 LEU A CA 1 ATOM 2069 C C . LEU A 1 259 ? 35.889 42.445 0.172 1.00 5.54 ? 259 LEU A C 1 ATOM 2070 O O . LEU A 1 259 ? 34.842 43.026 -0.119 1.00 5.65 ? 259 LEU A O 1 ATOM 2071 C CB . LEU A 1 259 ? 37.650 43.864 -0.830 1.00 6.92 ? 259 LEU A CB 1 ATOM 2072 C CG . LEU A 1 259 ? 38.395 44.270 0.445 1.00 6.27 ? 259 LEU A CG 1 ATOM 2073 C CD1 . LEU A 1 259 ? 39.646 43.406 0.686 1.00 8.34 ? 259 LEU A CD1 1 ATOM 2074 C CD2 . LEU A 1 259 ? 38.843 45.716 0.350 1.00 8.22 ? 259 LEU A CD2 1 ATOM 2075 N N . PHE A 1 260 ? 36.046 41.775 1.326 1.00 5.92 ? 260 PHE A N 1 ATOM 2076 C CA . PHE A 1 260 ? 34.985 41.744 2.309 1.00 5.57 ? 260 PHE A CA 1 ATOM 2077 C C . PHE A 1 260 ? 34.657 43.142 2.824 1.00 4.40 ? 260 PHE A C 1 ATOM 2078 O O . PHE A 1 260 ? 35.585 43.877 3.243 1.00 5.22 ? 260 PHE A O 1 ATOM 2079 C CB . PHE A 1 260 ? 35.354 40.810 3.479 1.00 5.96 ? 260 PHE A CB 1 ATOM 2080 C CG . PHE A 1 260 ? 34.256 40.640 4.484 1.00 6.74 ? 260 PHE A CG 1 ATOM 2081 C CD1 . PHE A 1 260 ? 33.291 39.681 4.277 1.00 9.60 ? 260 PHE A CD1 1 ATOM 2082 C CD2 . PHE A 1 260 ? 34.184 41.425 5.620 1.00 8.02 ? 260 PHE A CD2 1 ATOM 2083 C CE1 . PHE A 1 260 ? 32.263 39.504 5.211 1.00 11.08 ? 260 PHE A CE1 1 ATOM 2084 C CE2 . PHE A 1 260 ? 33.145 41.272 6.548 1.00 9.95 ? 260 PHE A CE2 1 ATOM 2085 C CZ . PHE A 1 260 ? 32.194 40.304 6.324 1.00 9.85 ? 260 PHE A CZ 1 ATOM 2086 N N . THR A 1 261 ? 33.364 43.506 2.785 1.00 4.76 ? 261 THR A N 1 ATOM 2087 C CA . THR A 1 261 ? 32.936 44.853 3.101 1.00 5.00 ? 261 THR A CA 1 ATOM 2088 C C . THR A 1 261 ? 31.816 44.797 4.126 1.00 4.38 ? 261 THR A C 1 ATOM 2089 O O . THR A 1 261 ? 30.860 44.037 3.979 1.00 6.16 ? 261 THR A O 1 ATOM 2090 C CB . THR A 1 261 ? 32.426 45.545 1.816 1.00 5.41 ? 261 THR A CB 1 ATOM 2091 O OG1 . THR A 1 261 ? 33.511 45.613 0.878 1.00 6.29 ? 261 THR A OG1 1 ATOM 2092 C CG2 . THR A 1 261 ? 31.998 46.980 2.109 1.00 6.13 ? 261 THR A CG2 1 ATOM 2093 N N . HIS A 1 262 ? 31.918 45.637 5.149 1.00 4.92 ? 262 HIS A N 1 ATOM 2094 C CA . HIS A 1 262 ? 30.850 45.817 6.115 1.00 4.85 ? 262 HIS A CA 1 ATOM 2095 C C . HIS A 1 262 ? 30.235 47.200 5.917 1.00 5.32 ? 262 HIS A C 1 ATOM 2096 O O . HIS A 1 262 ? 30.946 48.196 6.036 1.00 5.78 ? 262 HIS A O 1 ATOM 2097 C CB . HIS A 1 262 ? 31.472 45.765 7.525 1.00 5.87 ? 262 HIS A CB 1 ATOM 2098 C CG . HIS A 1 262 ? 30.510 46.104 8.622 1.00 5.75 ? 262 HIS A CG 1 ATOM 2099 N ND1 . HIS A 1 262 ? 29.946 45.139 9.431 1.00 6.63 ? 262 HIS A ND1 1 ATOM 2100 C CD2 . HIS A 1 262 ? 30.044 47.296 9.072 1.00 7.27 ? 262 HIS A CD2 1 ATOM 2101 C CE1 . HIS A 1 262 ? 29.174 45.724 10.339 1.00 9.22 ? 262 HIS A CE1 1 ATOM 2102 N NE2 . HIS A 1 262 ? 29.183 47.028 10.121 1.00 7.85 ? 262 HIS A NE2 1 ATOM 2103 N N . MET A 1 263 ? 28.939 47.257 5.634 1.00 4.98 ? 263 MET A N 1 ATOM 2104 C CA . MET A 1 263 ? 28.212 48.505 5.579 1.00 5.50 ? 263 MET A CA 1 ATOM 2105 C C . MET A 1 263 ? 27.481 48.708 6.890 1.00 6.35 ? 263 MET A C 1 ATOM 2106 O O . MET A 1 263 ? 26.717 47.811 7.335 1.00 6.55 ? 263 MET A O 1 ATOM 2107 C CB . MET A 1 263 ? 27.209 48.465 4.425 1.00 6.56 ? 263 MET A CB 1 ATOM 2108 C CG . MET A 1 263 ? 26.425 49.761 4.294 1.00 6.45 ? 263 MET A CG 1 ATOM 2109 S SD . MET A 1 263 ? 25.072 49.605 3.064 1.00 7.68 ? 263 MET A SD 1 ATOM 2110 C CE . MET A 1 263 ? 25.949 49.246 1.499 1.00 8.39 ? 263 MET A CE 1 ATOM 2111 N N A MET A 1 264 ? 27.722 49.847 7.541 0.50 5.50 ? 264 MET A N 1 ATOM 2112 N N B MET A 1 264 ? 27.712 49.843 7.549 0.50 6.02 ? 264 MET A N 1 ATOM 2113 C CA A MET A 1 264 ? 26.994 50.199 8.750 0.50 6.09 ? 264 MET A CA 1 ATOM 2114 C CA B MET A 1 264 ? 26.987 50.132 8.777 0.50 7.21 ? 264 MET A CA 1 ATOM 2115 C C A MET A 1 264 ? 25.524 50.415 8.397 0.50 6.43 ? 264 MET A C 1 ATOM 2116 C C B MET A 1 264 ? 25.540 50.481 8.443 0.50 7.11 ? 264 MET A C 1 ATOM 2117 O O A MET A 1 264 ? 25.195 50.816 7.264 0.50 6.33 ? 264 MET A O 1 ATOM 2118 O O B MET A 1 264 ? 25.252 51.062 7.386 0.50 7.52 ? 264 MET A O 1 ATOM 2119 C CB A MET A 1 264 ? 27.614 51.438 9.388 0.50 5.94 ? 264 MET A CB 1 ATOM 2120 C CB B MET A 1 264 ? 27.678 51.227 9.577 0.50 7.17 ? 264 MET A CB 1 ATOM 2121 C CG A MET A 1 264 ? 29.055 51.179 9.837 0.50 5.78 ? 264 MET A CG 1 ATOM 2122 C CG B MET A 1 264 ? 29.111 50.851 9.936 0.50 7.87 ? 264 MET A CG 1 ATOM 2123 S SD A MET A 1 264 ? 30.032 52.601 10.392 0.50 8.17 ? 264 MET A SD 1 ATOM 2124 S SD B MET A 1 264 ? 29.697 51.649 11.414 0.50 10.78 ? 264 MET A SD 1 ATOM 2125 C CE A MET A 1 264 ? 28.934 53.387 11.543 0.50 8.66 ? 264 MET A CE 1 ATOM 2126 C CE B MET A 1 264 ? 29.665 53.304 10.912 0.50 10.03 ? 264 MET A CE 1 ATOM 2127 N N . PRO A 1 265 ? 24.603 50.109 9.320 1.00 6.84 ? 265 PRO A N 1 ATOM 2128 C CA . PRO A 1 265 ? 23.186 50.115 8.938 1.00 7.06 ? 265 PRO A CA 1 ATOM 2129 C C . PRO A 1 265 ? 22.377 51.394 9.118 1.00 7.47 ? 265 PRO A C 1 ATOM 2130 O O . PRO A 1 265 ? 21.259 51.463 8.575 1.00 6.33 ? 265 PRO A O 1 ATOM 2131 C CB . PRO A 1 265 ? 22.600 49.035 9.852 1.00 7.89 ? 265 PRO A CB 1 ATOM 2132 C CG . PRO A 1 265 ? 23.416 49.068 11.041 1.00 8.65 ? 265 PRO A CG 1 ATOM 2133 C CD . PRO A 1 265 ? 24.815 49.583 10.700 1.00 7.05 ? 265 PRO A CD 1 ATOM 2134 N N . PHE A 1 266 ? 22.878 52.329 9.925 1.00 6.74 ? 266 PHE A N 1 ATOM 2135 C CA . PHE A 1 266 ? 22.088 53.459 10.417 1.00 7.45 ? 266 PHE A CA 1 ATOM 2136 C C . PHE A 1 266 ? 22.488 54.825 9.831 1.00 6.89 ? 266 PHE A C 1 ATOM 2137 O O . PHE A 1 266 ? 23.360 54.921 8.980 1.00 7.68 ? 266 PHE A O 1 ATOM 2138 C CB . PHE A 1 266 ? 22.049 53.439 11.953 1.00 7.12 ? 266 PHE A CB 1 ATOM 2139 C CG . PHE A 1 266 ? 21.506 52.119 12.546 1.00 7.23 ? 266 PHE A CG 1 ATOM 2140 C CD1 . PHE A 1 266 ? 20.361 51.508 12.038 1.00 9.21 ? 266 PHE A CD1 1 ATOM 2141 C CD2 . PHE A 1 266 ? 22.160 51.510 13.586 1.00 7.34 ? 266 PHE A CD2 1 ATOM 2142 C CE1 . PHE A 1 266 ? 19.866 50.324 12.613 1.00 7.42 ? 266 PHE A CE1 1 ATOM 2143 C CE2 . PHE A 1 266 ? 21.668 50.312 14.151 1.00 8.08 ? 266 PHE A CE2 1 ATOM 2144 C CZ . PHE A 1 266 ? 20.550 49.721 13.638 1.00 6.71 ? 266 PHE A CZ 1 ATOM 2145 N N . TYR A 1 267 ? 21.848 55.881 10.280 1.00 7.32 ? 267 TYR A N 1 ATOM 2146 C CA . TYR A 1 267 ? 21.882 57.154 9.598 1.00 6.85 ? 267 TYR A CA 1 ATOM 2147 C C . TYR A 1 267 ? 23.223 57.850 9.801 1.00 7.54 ? 267 TYR A C 1 ATOM 2148 O O . TYR A 1 267 ? 23.616 58.660 8.964 1.00 7.37 ? 267 TYR A O 1 ATOM 2149 C CB . TYR A 1 267 ? 20.759 58.017 10.186 1.00 8.75 ? 267 TYR A CB 1 ATOM 2150 C CG . TYR A 1 267 ? 20.866 59.509 10.000 1.00 8.34 ? 267 TYR A CG 1 ATOM 2151 C CD1 . TYR A 1 267 ? 20.485 60.121 8.815 1.00 10.98 ? 267 TYR A CD1 1 ATOM 2152 C CD2 . TYR A 1 267 ? 21.238 60.306 11.074 1.00 10.19 ? 267 TYR A CD2 1 ATOM 2153 C CE1 . TYR A 1 267 ? 20.557 61.519 8.694 1.00 10.30 ? 267 TYR A CE1 1 ATOM 2154 C CE2 . TYR A 1 267 ? 21.312 61.637 10.964 1.00 11.28 ? 267 TYR A CE2 1 ATOM 2155 C CZ . TYR A 1 267 ? 20.975 62.243 9.788 1.00 11.95 ? 267 TYR A CZ 1 ATOM 2156 O OH . TYR A 1 267 ? 21.042 63.632 9.743 1.00 15.75 ? 267 TYR A OH 1 ATOM 2157 N N . SER A 1 268 ? 23.913 57.575 10.893 1.00 7.34 ? 268 SER A N 1 ATOM 2158 C CA . SER A 1 268 ? 25.176 58.258 11.179 1.00 7.75 ? 268 SER A CA 1 ATOM 2159 C C . SER A 1 268 ? 26.177 57.324 11.827 1.00 7.61 ? 268 SER A C 1 ATOM 2160 O O . SER A 1 268 ? 25.822 56.201 12.238 1.00 7.64 ? 268 SER A O 1 ATOM 2161 C CB . SER A 1 268 ? 24.901 59.499 12.068 1.00 8.20 ? 268 SER A CB 1 ATOM 2162 O OG . SER A 1 268 ? 26.112 60.123 12.458 1.00 11.62 ? 268 SER A OG 1 ATOM 2163 N N . TYR A 1 269 ? 27.432 57.782 11.949 1.00 6.97 ? 269 TYR A N 1 ATOM 2164 C CA . TYR A 1 269 ? 28.435 57.058 12.712 1.00 6.99 ? 269 TYR A CA 1 ATOM 2165 C C . TYR A 1 269 ? 28.544 57.550 14.152 1.00 7.59 ? 269 TYR A C 1 ATOM 2166 O O . TYR A 1 269 ? 29.412 57.088 14.884 1.00 8.49 ? 269 TYR A O 1 ATOM 2167 C CB . TYR A 1 269 ? 29.829 57.190 12.050 1.00 6.94 ? 269 TYR A CB 1 ATOM 2168 C CG . TYR A 1 269 ? 30.249 58.622 11.791 1.00 7.57 ? 269 TYR A CG 1 ATOM 2169 C CD1 . TYR A 1 269 ? 30.680 59.436 12.836 1.00 8.12 ? 269 TYR A CD1 1 ATOM 2170 C CD2 . TYR A 1 269 ? 30.178 59.178 10.510 1.00 8.33 ? 269 TYR A CD2 1 ATOM 2171 C CE1 . TYR A 1 269 ? 31.061 60.748 12.634 1.00 8.62 ? 269 TYR A CE1 1 ATOM 2172 C CE2 . TYR A 1 269 ? 30.568 60.505 10.281 1.00 8.34 ? 269 TYR A CE2 1 ATOM 2173 C CZ . TYR A 1 269 ? 30.976 61.282 11.366 1.00 9.12 ? 269 TYR A CZ 1 ATOM 2174 O OH . TYR A 1 269 ? 31.333 62.594 11.113 1.00 10.76 ? 269 TYR A OH 1 ATOM 2175 N N . ASP A 1 270 ? 27.677 58.463 14.561 1.00 6.94 ? 270 ASP A N 1 ATOM 2176 C CA . ASP A 1 270 ? 27.749 58.973 15.929 1.00 7.23 ? 270 ASP A CA 1 ATOM 2177 C C . ASP A 1 270 ? 27.143 57.970 16.890 1.00 6.87 ? 270 ASP A C 1 ATOM 2178 O O . ASP A 1 270 ? 26.568 56.977 16.450 1.00 7.55 ? 270 ASP A O 1 ATOM 2179 C CB . ASP A 1 270 ? 27.127 60.364 16.025 1.00 8.08 ? 270 ASP A CB 1 ATOM 2180 C CG . ASP A 1 270 ? 25.641 60.394 15.782 1.00 12.02 ? 270 ASP A CG 1 ATOM 2181 O OD1 . ASP A 1 270 ? 24.978 59.339 15.601 1.00 11.77 ? 270 ASP A OD1 1 ATOM 2182 O OD2 . ASP A 1 270 ? 25.051 61.490 15.783 1.00 14.89 ? 270 ASP A OD2 1 ATOM 2183 N N . ILE A 1 271 ? 27.352 58.170 18.186 1.00 7.78 ? 271 ILE A N 1 ATOM 2184 C CA . ILE A 1 271 ? 26.936 57.148 19.148 1.00 7.06 ? 271 ILE A CA 1 ATOM 2185 C C . ILE A 1 271 ? 25.421 56.882 19.108 1.00 7.81 ? 271 ILE A C 1 ATOM 2186 O O . ILE A 1 271 ? 25.023 55.730 19.174 1.00 7.69 ? 271 ILE A O 1 ATOM 2187 C CB . ILE A 1 271 ? 27.494 57.457 20.522 1.00 7.76 ? 271 ILE A CB 1 ATOM 2188 C CG1 . ILE A 1 271 ? 29.025 57.328 20.479 1.00 6.68 ? 271 ILE A CG1 1 ATOM 2189 C CG2 . ILE A 1 271 ? 26.911 56.500 21.602 1.00 6.93 ? 271 ILE A CG2 1 ATOM 2190 C CD1 . ILE A 1 271 ? 29.689 57.962 21.678 1.00 8.26 ? 271 ILE A CD1 1 ATOM 2191 N N . PRO A 1 272 ? 24.583 57.908 19.005 1.00 7.45 ? 272 PRO A N 1 ATOM 2192 C CA . PRO A 1 272 ? 23.128 57.642 18.890 1.00 7.37 ? 272 PRO A CA 1 ATOM 2193 C C . PRO A 1 272 ? 22.757 56.706 17.760 1.00 7.03 ? 272 PRO A C 1 ATOM 2194 O O . PRO A 1 272 ? 21.679 56.085 17.809 1.00 8.70 ? 272 PRO A O 1 ATOM 2195 C CB . PRO A 1 272 ? 22.518 59.026 18.683 1.00 7.77 ? 272 PRO A CB 1 ATOM 2196 C CG . PRO A 1 272 ? 23.483 59.969 19.383 1.00 9.64 ? 272 PRO A CG 1 ATOM 2197 C CD . PRO A 1 272 ? 24.852 59.350 19.165 1.00 8.51 ? 272 PRO A CD 1 ATOM 2198 N N . HIS A 1 273 ? 23.585 56.657 16.704 1.00 6.72 ? 273 HIS A N 1 ATOM 2199 C CA . HIS A 1 273 ? 23.226 55.794 15.570 1.00 7.68 ? 273 HIS A CA 1 ATOM 2200 C C . HIS A 1 273 ? 24.144 54.611 15.389 1.00 7.93 ? 273 HIS A C 1 ATOM 2201 O O . HIS A 1 273 ? 24.168 54.006 14.320 1.00 8.65 ? 273 HIS A O 1 ATOM 2202 C CB . HIS A 1 273 ? 23.108 56.617 14.281 1.00 8.02 ? 273 HIS A CB 1 ATOM 2203 C CG . HIS A 1 273 ? 22.038 57.661 14.357 1.00 7.62 ? 273 HIS A CG 1 ATOM 2204 N ND1 . HIS A 1 273 ? 22.271 58.951 14.800 1.00 8.65 ? 273 HIS A ND1 1 ATOM 2205 C CD2 . HIS A 1 273 ? 20.712 57.601 14.056 1.00 7.45 ? 273 HIS A CD2 1 ATOM 2206 C CE1 . HIS A 1 273 ? 21.121 59.619 14.798 1.00 8.67 ? 273 HIS A CE1 1 ATOM 2207 N NE2 . HIS A 1 273 ? 20.170 58.824 14.352 1.00 9.44 ? 273 HIS A NE2 1 ATOM 2208 N N . THR A 1 274 ? 24.840 54.222 16.442 1.00 8.10 ? 274 THR A N 1 ATOM 2209 C CA . THR A 1 274 ? 25.715 53.056 16.330 1.00 8.31 ? 274 THR A CA 1 ATOM 2210 C C . THR A 1 274 ? 25.487 51.978 17.386 1.00 9.54 ? 274 THR A C 1 ATOM 2211 O O . THR A 1 274 ? 26.020 50.885 17.256 1.00 10.67 ? 274 THR A O 1 ATOM 2212 C CB . THR A 1 274 ? 27.210 53.432 16.287 1.00 9.14 ? 274 THR A CB 1 ATOM 2213 O OG1 . THR A 1 274 ? 27.478 54.378 17.332 1.00 8.78 ? 274 THR A OG1 1 ATOM 2214 C CG2 . THR A 1 274 ? 27.514 54.134 14.948 1.00 9.23 ? 274 THR A CG2 1 ATOM 2215 N N . CYS A 1 275 ? 24.714 52.252 18.433 1.00 10.14 ? 275 CYS A N 1 ATOM 2216 C CA . CYS A 1 275 ? 24.491 51.194 19.416 1.00 11.00 ? 275 CYS A CA 1 ATOM 2217 C C . CYS A 1 275 ? 23.358 50.242 19.006 1.00 10.08 ? 275 CYS A C 1 ATOM 2218 O O . CYS A 1 275 ? 23.263 49.114 19.468 1.00 10.55 ? 275 CYS A O 1 ATOM 2219 C CB . CYS A 1 275 ? 24.209 51.818 20.786 1.00 11.21 ? 275 CYS A CB 1 ATOM 2220 S SG . CYS A 1 275 ? 22.476 51.834 21.330 1.00 13.84 ? 275 CYS A SG 1 ATOM 2221 N N . GLY A 1 276 ? 22.455 50.717 18.166 1.00 9.21 ? 276 GLY A N 1 ATOM 2222 C CA . GLY A 1 276 ? 21.224 49.999 17.854 1.00 9.35 ? 276 GLY A CA 1 ATOM 2223 C C . GLY A 1 276 ? 20.281 50.916 17.127 1.00 9.30 ? 276 GLY A C 1 ATOM 2224 O O . GLY A 1 276 ? 20.655 52.039 16.779 1.00 9.27 ? 276 GLY A O 1 ATOM 2225 N N . PRO A 1 277 ? 19.067 50.452 16.817 1.00 8.51 ? 277 PRO A N 1 ATOM 2226 C CA . PRO A 1 277 ? 18.141 51.216 15.985 1.00 8.59 ? 277 PRO A CA 1 ATOM 2227 C C . PRO A 1 277 ? 17.459 52.397 16.599 1.00 8.56 ? 277 PRO A C 1 ATOM 2228 O O . PRO A 1 277 ? 16.875 53.120 15.807 1.00 9.19 ? 277 PRO A O 1 ATOM 2229 C CB . PRO A 1 277 ? 17.027 50.199 15.667 1.00 8.82 ? 277 PRO A CB 1 ATOM 2230 C CG . PRO A 1 277 ? 17.115 49.185 16.810 1.00 8.08 ? 277 PRO A CG 1 ATOM 2231 C CD . PRO A 1 277 ? 18.556 49.098 17.120 1.00 9.14 ? 277 PRO A CD 1 ATOM 2232 N N . ASP A 1 278 ? 17.470 52.545 17.917 1.00 8.95 ? 278 ASP A N 1 ATOM 2233 C CA . ASP A 1 278 ? 16.720 53.647 18.508 1.00 9.68 ? 278 ASP A CA 1 ATOM 2234 C C . ASP A 1 278 ? 17.667 54.694 19.083 1.00 9.23 ? 278 ASP A C 1 ATOM 2235 O O . ASP A 1 278 ? 18.275 54.469 20.132 1.00 9.20 ? 278 ASP A O 1 ATOM 2236 C CB . ASP A 1 278 ? 15.828 53.116 19.655 1.00 9.80 ? 278 ASP A CB 1 ATOM 2237 C CG . ASP A 1 278 ? 14.968 54.199 20.258 1.00 12.24 ? 278 ASP A CG 1 ATOM 2238 O OD1 . ASP A 1 278 ? 15.089 55.391 19.871 1.00 13.13 ? 278 ASP A OD1 1 ATOM 2239 O OD2 . ASP A 1 278 ? 14.098 53.889 21.108 1.00 15.09 ? 278 ASP A OD2 1 ATOM 2240 N N . PRO A 1 279 ? 17.810 55.828 18.401 1.00 9.52 ? 279 PRO A N 1 ATOM 2241 C CA . PRO A 1 279 ? 18.771 56.834 18.877 1.00 9.03 ? 279 PRO A CA 1 ATOM 2242 C C . PRO A 1 279 ? 18.412 57.427 20.227 1.00 9.05 ? 279 PRO A C 1 ATOM 2243 O O . PRO A 1 279 ? 19.276 57.890 20.927 1.00 9.37 ? 279 PRO A O 1 ATOM 2244 C CB . PRO A 1 279 ? 18.780 57.883 17.751 1.00 9.60 ? 279 PRO A CB 1 ATOM 2245 C CG . PRO A 1 279 ? 17.488 57.712 17.083 1.00 10.42 ? 279 PRO A CG 1 ATOM 2246 C CD . PRO A 1 279 ? 17.064 56.273 17.214 1.00 9.68 ? 279 PRO A CD 1 ATOM 2247 N N . LYS A 1 280 ? 17.136 57.405 20.600 1.00 9.17 ? 280 LYS A N 1 ATOM 2248 C CA . LYS A 1 280 ? 16.749 57.933 21.908 1.00 11.08 ? 280 LYS A CA 1 ATOM 2249 C C . LYS A 1 280 ? 17.345 57.096 23.028 1.00 10.58 ? 280 LYS A C 1 ATOM 2250 O O . LYS A 1 280 ? 17.696 57.614 24.089 1.00 11.47 ? 280 LYS A O 1 ATOM 2251 C CB . LYS A 1 280 ? 15.230 57.981 22.031 1.00 12.09 ? 280 LYS A CB 1 ATOM 2252 C CG . LYS A 1 280 ? 14.756 58.503 23.370 1.00 14.42 ? 280 LYS A CG 1 ATOM 2253 C CD . LYS A 1 280 ? 13.227 58.511 23.409 1.00 18.24 ? 280 LYS A CD 1 ATOM 2254 C CE . LYS A 1 280 ? 12.699 58.588 24.852 1.00 25.94 ? 280 LYS A CE 1 ATOM 2255 N NZ . LYS A 1 280 ? 13.239 57.502 25.776 1.00 30.84 ? 280 LYS A NZ 1 ATOM 2256 N N . VAL A 1 281 ? 17.508 55.796 22.780 1.00 10.33 ? 281 VAL A N 1 ATOM 2257 C CA . VAL A 1 281 ? 18.203 54.933 23.725 1.00 10.51 ? 281 VAL A CA 1 ATOM 2258 C C . VAL A 1 281 ? 19.714 55.023 23.606 1.00 10.13 ? 281 VAL A C 1 ATOM 2259 O O . VAL A 1 281 ? 20.411 55.167 24.596 1.00 9.21 ? 281 VAL A O 1 ATOM 2260 C CB . VAL A 1 281 ? 17.747 53.453 23.571 1.00 10.15 ? 281 VAL A CB 1 ATOM 2261 C CG1 . VAL A 1 281 ? 18.536 52.514 24.475 1.00 11.18 ? 281 VAL A CG1 1 ATOM 2262 C CG2 . VAL A 1 281 ? 16.238 53.331 23.832 1.00 10.43 ? 281 VAL A CG2 1 ATOM 2263 N N . CYS A 1 282 ? 20.230 54.922 22.370 1.00 9.39 ? 282 CYS A N 1 ATOM 2264 C CA . CYS A 1 282 ? 21.682 54.934 22.202 1.00 9.57 ? 282 CYS A CA 1 ATOM 2265 C C . CYS A 1 282 ? 22.311 56.232 22.696 1.00 8.66 ? 282 CYS A C 1 ATOM 2266 O O . CYS A 1 282 ? 23.417 56.213 23.212 1.00 8.97 ? 282 CYS A O 1 ATOM 2267 C CB . CYS A 1 282 ? 22.036 54.758 20.733 1.00 10.68 ? 282 CYS A CB 1 ATOM 2268 S SG . CYS A 1 282 ? 21.598 53.141 20.070 1.00 12.31 ? 282 CYS A SG 1 ATOM 2269 N N . CYS A 1 283 ? 21.593 57.344 22.542 1.00 9.14 ? 283 CYS A N 1 ATOM 2270 C CA . CYS A 1 283 ? 22.137 58.596 23.018 1.00 9.05 ? 283 CYS A CA 1 ATOM 2271 C C . CYS A 1 283 ? 22.431 58.614 24.524 1.00 8.88 ? 283 CYS A C 1 ATOM 2272 O O . CYS A 1 283 ? 23.321 59.341 24.978 1.00 9.06 ? 283 CYS A O 1 ATOM 2273 C CB . CYS A 1 283 ? 21.220 59.740 22.609 1.00 9.96 ? 283 CYS A CB 1 ATOM 2274 S SG . CYS A 1 283 ? 21.993 61.365 22.765 1.00 13.72 ? 283 CYS A SG 1 ATOM 2275 N N . GLN A 1 284 ? 21.687 57.784 25.284 1.00 9.35 ? 284 GLN A N 1 ATOM 2276 C CA . GLN A 1 284 ? 21.936 57.617 26.717 1.00 9.39 ? 284 GLN A CA 1 ATOM 2277 C C . GLN A 1 284 ? 23.212 56.881 27.062 1.00 9.26 ? 284 GLN A C 1 ATOM 2278 O O . GLN A 1 284 ? 23.565 56.784 28.229 1.00 10.26 ? 284 GLN A O 1 ATOM 2279 C CB . GLN A 1 284 ? 20.751 56.900 27.378 1.00 10.24 ? 284 GLN A CB 1 ATOM 2280 C CG . GLN A 1 284 ? 19.435 57.653 27.187 1.00 11.26 ? 284 GLN A CG 1 ATOM 2281 C CD . GLN A 1 284 ? 18.258 56.886 27.735 1.00 11.71 ? 284 GLN A CD 1 ATOM 2282 O OE1 . GLN A 1 284 ? 18.287 56.459 28.896 1.00 14.33 ? 284 GLN A OE1 1 ATOM 2283 N NE2 . GLN A 1 284 ? 17.264 56.674 26.906 1.00 13.35 ? 284 GLN A NE2 1 ATOM 2284 N N . PHE A 1 285 ? 23.897 56.366 26.032 1.00 8.46 ? 285 PHE A N 1 ATOM 2285 C CA . PHE A 1 285 ? 25.141 55.666 26.253 1.00 8.04 ? 285 PHE A CA 1 ATOM 2286 C C . PHE A 1 285 ? 26.296 56.408 25.602 1.00 7.54 ? 285 PHE A C 1 ATOM 2287 O O . PHE A 1 285 ? 27.360 55.831 25.399 1.00 8.28 ? 285 PHE A O 1 ATOM 2288 C CB . PHE A 1 285 ? 25.007 54.206 25.814 1.00 9.16 ? 285 PHE A CB 1 ATOM 2289 C CG . PHE A 1 285 ? 23.983 53.474 26.651 1.00 9.26 ? 285 PHE A CG 1 ATOM 2290 C CD1 . PHE A 1 285 ? 24.369 52.889 27.840 1.00 9.59 ? 285 PHE A CD1 1 ATOM 2291 C CD2 . PHE A 1 285 ? 22.629 53.441 26.275 1.00 10.58 ? 285 PHE A CD2 1 ATOM 2292 C CE1 . PHE A 1 285 ? 23.414 52.231 28.660 1.00 8.83 ? 285 PHE A CE1 1 ATOM 2293 C CE2 . PHE A 1 285 ? 21.666 52.809 27.092 1.00 11.46 ? 285 PHE A CE2 1 ATOM 2294 C CZ . PHE A 1 285 ? 22.082 52.202 28.275 1.00 10.62 ? 285 PHE A CZ 1 ATOM 2295 N N . ASP A 1 286 ? 26.052 57.700 25.335 1.00 7.34 ? 286 ASP A N 1 ATOM 2296 C CA . ASP A 1 286 ? 27.124 58.624 24.983 1.00 6.83 ? 286 ASP A CA 1 ATOM 2297 C C . ASP A 1 286 ? 27.378 59.484 26.222 1.00 7.00 ? 286 ASP A C 1 ATOM 2298 O O . ASP A 1 286 ? 26.665 60.468 26.467 1.00 8.46 ? 286 ASP A O 1 ATOM 2299 C CB . ASP A 1 286 ? 26.735 59.469 23.799 1.00 6.77 ? 286 ASP A CB 1 ATOM 2300 C CG . ASP A 1 286 ? 27.861 60.363 23.330 1.00 6.35 ? 286 ASP A CG 1 ATOM 2301 O OD1 . ASP A 1 286 ? 28.895 60.445 24.025 1.00 7.50 ? 286 ASP A OD1 1 ATOM 2302 O OD2 . ASP A 1 286 ? 27.687 61.048 22.282 1.00 7.93 ? 286 ASP A OD2 1 ATOM 2303 N N . PHE A 1 287 ? 28.365 59.072 27.011 1.00 7.37 ? 287 PHE A N 1 ATOM 2304 C CA . PHE A 1 287 ? 28.516 59.677 28.341 1.00 8.03 ? 287 PHE A CA 1 ATOM 2305 C C . PHE A 1 287 ? 29.104 61.059 28.317 1.00 9.06 ? 287 PHE A C 1 ATOM 2306 O O . PHE A 1 287 ? 29.235 61.703 29.364 1.00 10.27 ? 287 PHE A O 1 ATOM 2307 C CB . PHE A 1 287 ? 29.234 58.715 29.307 1.00 8.41 ? 287 PHE A CB 1 ATOM 2308 C CG . PHE A 1 287 ? 28.446 57.448 29.538 1.00 9.13 ? 287 PHE A CG 1 ATOM 2309 C CD1 . PHE A 1 287 ? 27.417 57.441 30.503 1.00 9.94 ? 287 PHE A CD1 1 ATOM 2310 C CD2 . PHE A 1 287 ? 28.629 56.318 28.757 1.00 10.37 ? 287 PHE A CD2 1 ATOM 2311 C CE1 . PHE A 1 287 ? 26.655 56.307 30.735 1.00 10.00 ? 287 PHE A CE1 1 ATOM 2312 C CE2 . PHE A 1 287 ? 27.862 55.170 28.972 1.00 11.53 ? 287 PHE A CE2 1 ATOM 2313 C CZ . PHE A 1 287 ? 26.852 55.167 29.961 1.00 9.51 ? 287 PHE A CZ 1 ATOM 2314 N N . LYS A 1 288 ? 29.435 61.549 27.119 1.00 8.26 ? 288 LYS A N 1 ATOM 2315 C CA . LYS A 1 288 ? 29.825 62.947 26.990 1.00 8.49 ? 288 LYS A CA 1 ATOM 2316 C C . LYS A 1 288 ? 28.614 63.887 26.956 1.00 9.61 ? 288 LYS A C 1 ATOM 2317 O O . LYS A 1 288 ? 28.790 65.106 26.956 1.00 10.77 ? 288 LYS A O 1 ATOM 2318 C CB . LYS A 1 288 ? 30.688 63.149 25.718 1.00 9.05 ? 288 LYS A CB 1 ATOM 2319 C CG . LYS A 1 288 ? 31.545 64.415 25.802 1.00 8.30 ? 288 LYS A CG 1 ATOM 2320 C CD . LYS A 1 288 ? 32.430 64.579 24.543 1.00 10.07 ? 288 LYS A CD 1 ATOM 2321 C CE . LYS A 1 288 ? 33.199 65.873 24.674 1.00 9.72 ? 288 LYS A CE 1 ATOM 2322 N NZ . LYS A 1 288 ? 34.382 65.951 23.716 1.00 12.14 ? 288 LYS A NZ 1 ATOM 2323 N N . ARG A 1 289 ? 27.383 63.361 26.939 1.00 9.98 ? 289 ARG A N 1 ATOM 2324 C CA . ARG A 1 289 ? 26.210 64.212 26.783 1.00 11.27 ? 289 ARG A CA 1 ATOM 2325 C C . ARG A 1 289 ? 25.431 64.519 28.091 1.00 12.58 ? 289 ARG A C 1 ATOM 2326 O O . ARG A 1 289 ? 24.238 64.766 28.039 1.00 13.01 ? 289 ARG A O 1 ATOM 2327 C CB . ARG A 1 289 ? 25.261 63.583 25.767 1.00 10.80 ? 289 ARG A CB 1 ATOM 2328 C CG . ARG A 1 289 ? 25.861 63.457 24.379 1.00 10.40 ? 289 ARG A CG 1 ATOM 2329 C CD . ARG A 1 289 ? 24.862 62.998 23.379 1.00 11.80 ? 289 ARG A CD 1 ATOM 2330 N NE . ARG A 1 289 ? 25.412 62.706 22.047 1.00 9.45 ? 289 ARG A NE 1 ATOM 2331 C CZ . ARG A 1 289 ? 25.018 63.270 20.928 1.00 11.28 ? 289 ARG A CZ 1 ATOM 2332 N NH1 . ARG A 1 289 ? 24.051 64.201 20.897 1.00 12.11 ? 289 ARG A NH1 1 ATOM 2333 N NH2 . ARG A 1 289 ? 25.562 62.835 19.805 1.00 10.01 ? 289 ARG A NH2 1 ATOM 2334 N N . MET A 1 290 ? 26.092 64.482 29.245 1.00 15.63 ? 290 MET A N 1 ATOM 2335 C CA . MET A 1 290 ? 25.350 64.752 30.498 1.00 17.93 ? 290 MET A CA 1 ATOM 2336 C C . MET A 1 290 ? 25.241 66.246 30.879 1.00 19.30 ? 290 MET A C 1 ATOM 2337 O O . MET A 1 290 ? 24.410 66.617 31.740 1.00 21.25 ? 290 MET A O 1 ATOM 2338 C CB . MET A 1 290 ? 25.826 63.848 31.657 1.00 17.18 ? 290 MET A CB 1 ATOM 2339 C CG . MET A 1 290 ? 25.714 62.390 31.318 1.00 19.33 ? 290 MET A CG 1 ATOM 2340 S SD . MET A 1 290 ? 26.093 61.232 32.644 1.00 21.13 ? 290 MET A SD 1 ATOM 2341 C CE . MET A 1 290 ? 27.893 61.193 32.509 1.00 20.21 ? 290 MET A CE 1 ATOM 2342 N N . GLY A 1 291 ? 26.050 67.101 30.238 1.00 19.22 ? 291 GLY A N 1 ATOM 2343 C CA . GLY A 1 291 ? 25.915 68.544 30.398 1.00 18.75 ? 291 GLY A CA 1 ATOM 2344 C C . GLY A 1 291 ? 27.197 69.371 30.482 1.00 18.68 ? 291 GLY A C 1 ATOM 2345 O O . GLY A 1 291 ? 27.315 70.438 29.840 1.00 19.34 ? 291 GLY A O 1 ATOM 2346 N N . SER A 1 292 ? 28.159 68.902 31.279 1.00 16.95 ? 292 SER A N 1 ATOM 2347 C CA . SER A 1 292 ? 29.402 69.638 31.516 1.00 15.15 ? 292 SER A CA 1 ATOM 2348 C C . SER A 1 292 ? 30.278 69.833 30.265 1.00 13.46 ? 292 SER A C 1 ATOM 2349 O O . SER A 1 292 ? 31.145 70.713 30.250 1.00 12.11 ? 292 SER A O 1 ATOM 2350 C CB . SER A 1 292 ? 30.214 68.939 32.609 1.00 15.48 ? 292 SER A CB 1 ATOM 2351 O OG . SER A 1 292 ? 30.686 67.682 32.144 1.00 17.76 ? 292 SER A OG 1 ATOM 2352 N N . PHE A 1 293 ? 30.060 69.014 29.234 1.00 11.64 ? 293 PHE A N 1 ATOM 2353 C CA . PHE A 1 293 ? 30.798 69.123 27.974 1.00 12.23 ? 293 PHE A CA 1 ATOM 2354 C C . PHE A 1 293 ? 30.065 69.961 26.934 1.00 12.38 ? 293 PHE A C 1 ATOM 2355 O O . PHE A 1 293 ? 30.517 70.039 25.794 1.00 13.00 ? 293 PHE A O 1 ATOM 2356 C CB . PHE A 1 293 ? 31.110 67.734 27.398 1.00 12.11 ? 293 PHE A CB 1 ATOM 2357 C CG . PHE A 1 293 ? 31.977 66.889 28.280 1.00 10.67 ? 293 PHE A CG 1 ATOM 2358 C CD1 . PHE A 1 293 ? 33.355 66.975 28.207 1.00 10.91 ? 293 PHE A CD1 1 ATOM 2359 C CD2 . PHE A 1 293 ? 31.401 65.972 29.125 1.00 11.53 ? 293 PHE A CD2 1 ATOM 2360 C CE1 . PHE A 1 293 ? 34.172 66.165 28.998 1.00 11.43 ? 293 PHE A CE1 1 ATOM 2361 C CE2 . PHE A 1 293 ? 32.206 65.147 29.941 1.00 12.04 ? 293 PHE A CE2 1 ATOM 2362 C CZ . PHE A 1 293 ? 33.581 65.269 29.872 1.00 12.57 ? 293 PHE A CZ 1 ATOM 2363 N N . GLY A 1 294 ? 28.941 70.556 27.316 1.00 12.32 ? 294 GLY A N 1 ATOM 2364 C CA . GLY A 1 294 ? 28.179 71.371 26.388 1.00 13.31 ? 294 GLY A CA 1 ATOM 2365 C C . GLY A 1 294 ? 27.458 70.568 25.314 1.00 14.19 ? 294 GLY A C 1 ATOM 2366 O O . GLY A 1 294 ? 27.147 71.094 24.237 1.00 15.66 ? 294 GLY A O 1 ATOM 2367 N N . LEU A 1 295 ? 27.229 69.286 25.581 1.00 13.10 ? 295 LEU A N 1 ATOM 2368 C CA . LEU A 1 295 ? 26.466 68.462 24.678 1.00 13.01 ? 295 LEU A CA 1 ATOM 2369 C C . LEU A 1 295 ? 25.226 67.951 25.383 1.00 13.55 ? 295 LEU A C 1 ATOM 2370 O O . LEU A 1 295 ? 25.194 67.838 26.606 1.00 14.11 ? 295 LEU A O 1 ATOM 2371 C CB . LEU A 1 295 ? 27.299 67.289 24.180 1.00 13.00 ? 295 LEU A CB 1 ATOM 2372 C CG . LEU A 1 295 ? 28.634 67.646 23.528 1.00 13.69 ? 295 LEU A CG 1 ATOM 2373 C CD1 . LEU A 1 295 ? 29.432 66.379 23.253 1.00 15.28 ? 295 LEU A CD1 1 ATOM 2374 C CD2 . LEU A 1 295 ? 28.412 68.416 22.227 1.00 15.84 ? 295 LEU A CD2 1 ATOM 2375 N N . SER A 1 296 ? 24.203 67.661 24.596 1.00 13.97 ? 296 SER A N 1 ATOM 2376 C CA . SER A 1 296 ? 22.967 67.103 25.144 1.00 15.02 ? 296 SER A CA 1 ATOM 2377 C C . SER A 1 296 ? 22.388 66.087 24.170 1.00 15.30 ? 296 SER A C 1 ATOM 2378 O O . SER A 1 296 ? 22.946 65.869 23.091 1.00 14.04 ? 296 SER A O 1 ATOM 2379 C CB . SER A 1 296 ? 21.992 68.232 25.479 1.00 15.27 ? 296 SER A CB 1 ATOM 2380 O OG . SER A 1 296 ? 21.698 68.988 24.322 1.00 17.08 ? 296 SER A OG 1 ATOM 2381 N N . CYS A 1 297 ? 21.296 65.424 24.563 1.00 15.09 ? 297 CYS A N 1 ATOM 2382 C CA . CYS A 1 297 ? 20.592 64.484 23.677 1.00 15.21 ? 297 CYS A CA 1 ATOM 2383 C C . CYS A 1 297 ? 19.361 65.135 23.015 1.00 15.01 ? 297 CYS A C 1 ATOM 2384 O O . CYS A 1 297 ? 18.459 65.584 23.729 1.00 15.20 ? 297 CYS A O 1 ATOM 2385 C CB . CYS A 1 297 ? 20.175 63.213 24.453 1.00 15.31 ? 297 CYS A CB 1 ATOM 2386 S SG . CYS A 1 297 ? 21.566 62.033 24.693 1.00 19.59 ? 297 CYS A SG 1 ATOM 2387 N N . PRO A 1 298 ? 19.328 65.224 21.682 1.00 15.42 ? 298 PRO A N 1 ATOM 2388 C CA . PRO A 1 298 ? 18.184 65.763 20.928 1.00 15.78 ? 298 PRO A CA 1 ATOM 2389 C C . PRO A 1 298 ? 16.869 65.057 21.282 1.00 15.49 ? 298 PRO A C 1 ATOM 2390 O O . PRO A 1 298 ? 15.783 65.641 21.132 1.00 16.33 ? 298 PRO A O 1 ATOM 2391 C CB . PRO A 1 298 ? 18.541 65.406 19.475 1.00 17.26 ? 298 PRO A CB 1 ATOM 2392 C CG . PRO A 1 298 ? 19.976 65.367 19.433 1.00 17.44 ? 298 PRO A CG 1 ATOM 2393 C CD . PRO A 1 298 ? 20.443 64.877 20.773 1.00 15.42 ? 298 PRO A CD 1 ATOM 2394 N N . TRP A 1 299 ? 16.970 63.801 21.700 1.00 14.86 ? 299 TRP A N 1 ATOM 2395 C CA . TRP A 1 299 ? 15.781 62.988 21.992 1.00 14.46 ? 299 TRP A CA 1 ATOM 2396 C C . TRP A 1 299 ? 15.309 63.163 23.428 1.00 15.18 ? 299 TRP A C 1 ATOM 2397 O O . TRP A 1 299 ? 14.341 62.513 23.849 1.00 14.88 ? 299 TRP A O 1 ATOM 2398 C CB . TRP A 1 299 ? 16.029 61.497 21.657 1.00 13.69 ? 299 TRP A CB 1 ATOM 2399 C CG . TRP A 1 299 ? 16.372 61.346 20.224 1.00 12.30 ? 299 TRP A CG 1 ATOM 2400 C CD1 . TRP A 1 299 ? 15.506 61.141 19.199 1.00 12.69 ? 299 TRP A CD1 1 ATOM 2401 C CD2 . TRP A 1 299 ? 17.677 61.440 19.639 1.00 11.90 ? 299 TRP A CD2 1 ATOM 2402 N NE1 . TRP A 1 299 ? 16.184 61.089 18.001 1.00 13.23 ? 299 TRP A NE1 1 ATOM 2403 C CE2 . TRP A 1 299 ? 17.519 61.264 18.242 1.00 10.75 ? 299 TRP A CE2 1 ATOM 2404 C CE3 . TRP A 1 299 ? 18.957 61.628 20.153 1.00 10.82 ? 299 TRP A CE3 1 ATOM 2405 C CZ2 . TRP A 1 299 ? 18.597 61.316 17.343 1.00 11.04 ? 299 TRP A CZ2 1 ATOM 2406 C CZ3 . TRP A 1 299 ? 20.030 61.670 19.262 1.00 11.54 ? 299 TRP A CZ3 1 ATOM 2407 C CH2 . TRP A 1 299 ? 19.833 61.511 17.874 1.00 10.99 ? 299 TRP A CH2 1 ATOM 2408 N N . LYS A 1 300 ? 16.008 64.023 24.174 1.00 14.40 ? 300 LYS A N 1 ATOM 2409 C CA . LYS A 1 300 ? 15.501 64.567 25.460 1.00 15.74 ? 300 LYS A CA 1 ATOM 2410 C C . LYS A 1 300 ? 15.610 63.630 26.645 1.00 15.92 ? 300 LYS A C 1 ATOM 2411 O O . LYS A 1 300 ? 15.103 63.936 27.746 1.00 17.00 ? 300 LYS A O 1 ATOM 2412 C CB . LYS A 1 300 ? 14.062 65.079 25.325 1.00 16.42 ? 300 LYS A CB 1 ATOM 2413 C CG . LYS A 1 300 ? 13.927 66.171 24.327 1.00 19.31 ? 300 LYS A CG 1 ATOM 2414 C CD . LYS A 1 300 ? 12.487 66.666 24.235 1.00 23.71 ? 300 LYS A CD 1 ATOM 2415 C CE . LYS A 1 300 ? 12.340 67.676 23.106 1.00 27.11 ? 300 LYS A CE 1 ATOM 2416 N NZ . LYS A 1 300 ? 11.304 68.709 23.435 1.00 30.36 ? 300 LYS A NZ 1 ATOM 2417 N N . VAL A 1 301 ? 16.268 62.492 26.465 1.00 15.02 ? 301 VAL A N 1 ATOM 2418 C CA . VAL A 1 301 ? 16.591 61.651 27.608 1.00 14.49 ? 301 VAL A CA 1 ATOM 2419 C C . VAL A 1 301 ? 18.114 61.620 27.754 1.00 14.25 ? 301 VAL A C 1 ATOM 2420 O O . VAL A 1 301 ? 18.799 61.107 26.856 1.00 15.42 ? 301 VAL A O 1 ATOM 2421 C CB . VAL A 1 301 ? 16.066 60.205 27.469 1.00 14.39 ? 301 VAL A CB 1 ATOM 2422 C CG1 . VAL A 1 301 ? 16.357 59.443 28.746 1.00 15.05 ? 301 VAL A CG1 1 ATOM 2423 C CG2 . VAL A 1 301 ? 14.580 60.188 27.189 1.00 16.38 ? 301 VAL A CG2 1 ATOM 2424 N N . PRO A 1 302 ? 18.656 62.165 28.837 1.00 13.25 ? 302 PRO A N 1 ATOM 2425 C CA . PRO A 1 302 ? 20.105 62.264 28.974 1.00 13.89 ? 302 PRO A CA 1 ATOM 2426 C C . PRO A 1 302 ? 20.718 60.935 29.373 1.00 13.37 ? 302 PRO A C 1 ATOM 2427 O O . PRO A 1 302 ? 20.035 60.054 29.883 1.00 13.29 ? 302 PRO A O 1 ATOM 2428 C CB . PRO A 1 302 ? 20.281 63.318 30.080 1.00 14.39 ? 302 PRO A CB 1 ATOM 2429 C CG . PRO A 1 302 ? 19.030 63.204 30.909 1.00 15.44 ? 302 PRO A CG 1 ATOM 2430 C CD . PRO A 1 302 ? 17.944 62.751 30.004 1.00 14.13 ? 302 PRO A CD 1 ATOM 2431 N N . PRO A 1 303 ? 22.022 60.790 29.178 1.00 12.15 ? 303 PRO A N 1 ATOM 2432 C CA . PRO A 1 303 ? 22.720 59.658 29.780 1.00 12.15 ? 303 PRO A CA 1 ATOM 2433 C C . PRO A 1 303 ? 22.670 59.794 31.286 1.00 14.12 ? 303 PRO A C 1 ATOM 2434 O O . PRO A 1 303 ? 22.585 60.916 31.816 1.00 14.94 ? 303 PRO A O 1 ATOM 2435 C CB . PRO A 1 303 ? 24.179 59.835 29.307 1.00 11.75 ? 303 PRO A CB 1 ATOM 2436 C CG . PRO A 1 303 ? 24.140 60.904 28.255 1.00 13.64 ? 303 PRO A CG 1 ATOM 2437 C CD . PRO A 1 303 ? 22.935 61.709 28.476 1.00 13.41 ? 303 PRO A CD 1 ATOM 2438 N N . ARG A 1 304 ? 22.747 58.653 31.962 1.00 14.46 ? 304 ARG A N 1 ATOM 2439 C CA . ARG A 1 304 ? 22.916 58.631 33.404 1.00 15.50 ? 304 ARG A CA 1 ATOM 2440 C C . ARG A 1 304 ? 24.146 57.814 33.753 1.00 13.85 ? 304 ARG A C 1 ATOM 2441 O O . ARG A 1 304 ? 24.392 56.756 33.136 1.00 12.38 ? 304 ARG A O 1 ATOM 2442 C CB . ARG A 1 304 ? 21.680 58.044 34.081 1.00 17.42 ? 304 ARG A CB 1 ATOM 2443 C CG . ARG A 1 304 ? 20.482 58.992 33.996 1.00 21.65 ? 304 ARG A CG 1 ATOM 2444 C CD . ARG A 1 304 ? 19.244 58.515 34.707 1.00 28.59 ? 304 ARG A CD 1 ATOM 2445 N NE . ARG A 1 304 ? 18.393 57.689 33.847 1.00 32.07 ? 304 ARG A NE 1 ATOM 2446 C CZ . ARG A 1 304 ? 18.121 56.404 34.069 1.00 35.00 ? 304 ARG A CZ 1 ATOM 2447 N NH1 . ARG A 1 304 ? 18.630 55.776 35.125 1.00 34.96 ? 304 ARG A NH1 1 ATOM 2448 N NH2 . ARG A 1 304 ? 17.325 55.745 33.236 1.00 36.04 ? 304 ARG A NH2 1 ATOM 2449 N N . THR A 1 305 ? 24.925 58.313 34.703 1.00 12.94 ? 305 THR A N 1 ATOM 2450 C CA . THR A 1 305 ? 26.100 57.620 35.199 1.00 13.12 ? 305 THR A CA 1 ATOM 2451 C C . THR A 1 305 ? 25.717 56.215 35.643 1.00 12.57 ? 305 THR A C 1 ATOM 2452 O O . THR A 1 305 ? 24.687 56.039 36.320 1.00 13.37 ? 305 THR A O 1 ATOM 2453 C CB . THR A 1 305 ? 26.697 58.400 36.372 1.00 13.45 ? 305 THR A CB 1 ATOM 2454 O OG1 . THR A 1 305 ? 27.204 59.645 35.860 1.00 16.52 ? 305 THR A OG1 1 ATOM 2455 C CG2 . THR A 1 305 ? 27.891 57.714 36.962 1.00 15.42 ? 305 THR A CG2 1 ATOM 2456 N N . ILE A 1 306 ? 26.468 55.212 35.199 1.00 11.75 ? 306 ILE A N 1 ATOM 2457 C CA . ILE A 1 306 ? 26.182 53.829 35.601 1.00 11.62 ? 306 ILE A CA 1 ATOM 2458 C C . ILE A 1 306 ? 26.616 53.610 37.050 1.00 13.44 ? 306 ILE A C 1 ATOM 2459 O O . ILE A 1 306 ? 27.725 53.952 37.449 1.00 13.96 ? 306 ILE A O 1 ATOM 2460 C CB . ILE A 1 306 ? 26.863 52.816 34.624 1.00 11.68 ? 306 ILE A CB 1 ATOM 2461 C CG1 . ILE A 1 306 ? 26.508 53.090 33.149 1.00 10.29 ? 306 ILE A CG1 1 ATOM 2462 C CG2 . ILE A 1 306 ? 26.515 51.353 35.003 1.00 13.09 ? 306 ILE A CG2 1 ATOM 2463 C CD1 . ILE A 1 306 ? 25.039 53.080 32.831 1.00 12.45 ? 306 ILE A CD1 1 ATOM 2464 N N . SER A 1 307 ? 25.718 52.986 37.824 1.00 15.16 ? 307 SER A N 1 ATOM 2465 C CA . SER A 1 307 ? 25.929 52.710 39.235 1.00 17.03 ? 307 SER A CA 1 ATOM 2466 C C . SER A 1 307 ? 25.432 51.301 39.505 1.00 17.68 ? 307 SER A C 1 ATOM 2467 O O . SER A 1 307 ? 24.711 50.724 38.691 1.00 16.84 ? 307 SER A O 1 ATOM 2468 C CB . SER A 1 307 ? 25.065 53.662 40.073 1.00 16.83 ? 307 SER A CB 1 ATOM 2469 O OG . SER A 1 307 ? 23.687 53.374 39.919 1.00 17.18 ? 307 SER A OG 1 ATOM 2470 N N . ASP A 1 308 ? 25.694 50.795 40.702 1.00 18.84 ? 308 ASP A N 1 ATOM 2471 C CA . ASP A 1 308 ? 25.093 49.507 41.085 1.00 20.31 ? 308 ASP A CA 1 ATOM 2472 C C . ASP A 1 308 ? 23.551 49.464 41.080 1.00 19.62 ? 308 ASP A C 1 ATOM 2473 O O . ASP A 1 308 ? 22.988 48.414 40.752 1.00 19.19 ? 308 ASP A O 1 ATOM 2474 C CB . ASP A 1 308 ? 25.652 48.979 42.410 1.00 22.88 ? 308 ASP A CB 1 ATOM 2475 C CG . ASP A 1 308 ? 27.183 48.977 42.468 1.00 25.82 ? 308 ASP A CG 1 ATOM 2476 O OD1 . ASP A 1 308 ? 27.879 48.805 41.434 1.00 30.98 ? 308 ASP A OD1 1 ATOM 2477 O OD2 . ASP A 1 308 ? 27.791 49.137 43.549 1.00 32.34 ? 308 ASP A OD2 1 ATOM 2478 N N A GLN A 1 309 ? 22.880 50.577 41.393 0.50 18.41 ? 309 GLN A N 1 ATOM 2479 N N B GLN A 1 309 ? 22.899 50.571 41.444 0.50 19.40 ? 309 GLN A N 1 ATOM 2480 C CA A GLN A 1 309 ? 21.404 50.633 41.469 0.50 17.90 ? 309 GLN A CA 1 ATOM 2481 C CA B GLN A 1 309 ? 21.436 50.656 41.470 0.50 19.73 ? 309 GLN A CA 1 ATOM 2482 C C A GLN A 1 309 ? 20.726 50.841 40.127 0.50 17.34 ? 309 GLN A C 1 ATOM 2483 C C B GLN A 1 309 ? 20.849 50.496 40.088 0.50 19.08 ? 309 GLN A C 1 ATOM 2484 O O A GLN A 1 309 ? 19.488 50.806 40.021 0.50 15.24 ? 309 GLN A O 1 ATOM 2485 O O B GLN A 1 309 ? 19.771 49.921 39.927 0.50 19.92 ? 309 GLN A O 1 ATOM 2486 C CB A GLN A 1 309 ? 20.913 51.731 42.431 0.50 17.63 ? 309 GLN A CB 1 ATOM 2487 C CB B GLN A 1 309 ? 20.944 52.016 41.983 0.50 19.75 ? 309 GLN A CB 1 ATOM 2488 C CG A GLN A 1 309 ? 21.398 51.597 43.868 0.50 17.76 ? 309 GLN A CG 1 ATOM 2489 C CG B GLN A 1 309 ? 21.011 52.295 43.469 0.50 21.07 ? 309 GLN A CG 1 ATOM 2490 C CD A GLN A 1 309 ? 22.875 51.878 44.014 0.50 17.54 ? 309 GLN A CD 1 ATOM 2491 C CD B GLN A 1 309 ? 20.617 53.735 43.751 0.50 20.20 ? 309 GLN A CD 1 ATOM 2492 O OE1 A GLN A 1 309 ? 23.371 52.916 43.550 0.50 16.46 ? 309 GLN A OE1 1 ATOM 2493 O OE1 B GLN A 1 309 ? 19.721 54.278 43.094 0.50 20.15 ? 309 GLN A OE1 1 ATOM 2494 N NE2 A GLN A 1 309 ? 23.589 50.956 44.646 0.50 18.24 ? 309 GLN A NE2 1 ATOM 2495 N NE2 B GLN A 1 309 ? 21.304 54.369 44.684 0.50 22.56 ? 309 GLN A NE2 1 ATOM 2496 N N . ASN A 1 310 ? 21.525 51.066 39.089 1.00 17.24 ? 310 ASN A N 1 ATOM 2497 C CA . ASN A 1 310 ? 20.926 51.195 37.789 1.00 15.87 ? 310 ASN A CA 1 ATOM 2498 C C . ASN A 1 310 ? 21.557 50.279 36.746 1.00 13.98 ? 310 ASN A C 1 ATOM 2499 O O . ASN A 1 310 ? 21.003 50.191 35.688 1.00 14.15 ? 310 ASN A O 1 ATOM 2500 C CB . ASN A 1 310 ? 20.862 52.657 37.323 1.00 15.07 ? 310 ASN A CB 1 ATOM 2501 C CG . ASN A 1 310 ? 22.239 53.220 36.964 1.00 14.97 ? 310 ASN A CG 1 ATOM 2502 O OD1 . ASN A 1 310 ? 23.212 52.477 36.744 1.00 14.08 ? 310 ASN A OD1 1 ATOM 2503 N ND2 . ASN A 1 310 ? 22.321 54.539 36.929 1.00 16.22 ? 310 ASN A ND2 1 ATOM 2504 N N . VAL A 1 311 ? 22.658 49.613 37.069 1.00 13.26 ? 311 VAL A N 1 ATOM 2505 C CA . VAL A 1 311 ? 23.416 48.914 36.004 1.00 13.38 ? 311 VAL A CA 1 ATOM 2506 C C . VAL A 1 311 ? 22.557 47.803 35.406 1.00 14.02 ? 311 VAL A C 1 ATOM 2507 O O . VAL A 1 311 ? 22.582 47.600 34.198 1.00 13.46 ? 311 VAL A O 1 ATOM 2508 C CB . VAL A 1 311 ? 24.788 48.395 36.435 1.00 13.30 ? 311 VAL A CB 1 ATOM 2509 C CG1 . VAL A 1 311 ? 24.684 47.305 37.521 1.00 15.22 ? 311 VAL A CG1 1 ATOM 2510 C CG2 . VAL A 1 311 ? 25.590 47.887 35.210 1.00 14.07 ? 311 VAL A CG2 1 ATOM 2511 N N . ALA A 1 312 ? 21.756 47.107 36.216 1.00 13.61 ? 312 ALA A N 1 ATOM 2512 C CA . ALA A 1 312 ? 20.936 46.037 35.637 1.00 13.96 ? 312 ALA A CA 1 ATOM 2513 C C . ALA A 1 312 ? 19.960 46.588 34.623 1.00 13.77 ? 312 ALA A C 1 ATOM 2514 O O . ALA A 1 312 ? 19.806 46.034 33.518 1.00 14.44 ? 312 ALA A O 1 ATOM 2515 C CB . ALA A 1 312 ? 20.189 45.237 36.741 1.00 14.60 ? 312 ALA A CB 1 ATOM 2516 N N . ALA A 1 313 ? 19.285 47.688 34.955 1.00 14.09 ? 313 ALA A N 1 ATOM 2517 C CA . ALA A 1 313 ? 18.303 48.286 34.055 1.00 13.65 ? 313 ALA A CA 1 ATOM 2518 C C . ALA A 1 313 ? 18.969 48.867 32.794 1.00 13.35 ? 313 ALA A C 1 ATOM 2519 O O . ALA A 1 313 ? 18.480 48.690 31.696 1.00 13.28 ? 313 ALA A O 1 ATOM 2520 C CB . ALA A 1 313 ? 17.485 49.390 34.757 1.00 14.79 ? 313 ALA A CB 1 ATOM 2521 N N . ARG A 1 314 ? 20.060 49.591 33.001 1.00 12.92 ? 314 ARG A N 1 ATOM 2522 C CA . ARG A 1 314 ? 20.806 50.198 31.882 1.00 11.95 ? 314 ARG A CA 1 ATOM 2523 C C . ARG A 1 314 ? 21.311 49.113 30.937 1.00 10.97 ? 314 ARG A C 1 ATOM 2524 O O . ARG A 1 314 ? 21.233 49.288 29.717 1.00 11.67 ? 314 ARG A O 1 ATOM 2525 C CB . ARG A 1 314 ? 21.990 50.965 32.431 1.00 10.85 ? 314 ARG A CB 1 ATOM 2526 C CG . ARG A 1 314 ? 21.621 52.185 33.272 1.00 13.24 ? 314 ARG A CG 1 ATOM 2527 C CD . ARG A 1 314 ? 21.318 53.453 32.456 1.00 16.74 ? 314 ARG A CD 1 ATOM 2528 N NE . ARG A 1 314 ? 19.942 53.492 31.991 1.00 17.12 ? 314 ARG A NE 1 ATOM 2529 C CZ . ARG A 1 314 ? 19.436 54.391 31.157 1.00 16.89 ? 314 ARG A CZ 1 ATOM 2530 N NH1 . ARG A 1 314 ? 20.206 55.340 30.618 1.00 17.35 ? 314 ARG A NH1 1 ATOM 2531 N NH2 . ARG A 1 314 ? 18.154 54.346 30.836 1.00 19.07 ? 314 ARG A NH2 1 ATOM 2532 N N . SER A 1 315 ? 21.798 48.012 31.499 1.00 12.54 ? 315 SER A N 1 ATOM 2533 C CA . SER A 1 315 ? 22.311 46.894 30.697 1.00 12.04 ? 315 SER A CA 1 ATOM 2534 C C . SER A 1 315 ? 21.210 46.253 29.905 1.00 13.44 ? 315 SER A C 1 ATOM 2535 O O . SER A 1 315 ? 21.413 45.847 28.748 1.00 13.47 ? 315 SER A O 1 ATOM 2536 C CB . SER A 1 315 ? 22.952 45.850 31.595 1.00 11.75 ? 315 SER A CB 1 ATOM 2537 O OG . SER A 1 315 ? 24.151 46.299 32.161 1.00 12.01 ? 315 SER A OG 1 ATOM 2538 N N . ASP A 1 316 ? 20.036 46.083 30.518 1.00 12.85 ? 316 ASP A N 1 ATOM 2539 C CA A ASP A 1 316 ? 18.902 45.555 29.794 0.50 13.30 ? 316 ASP A CA 1 ATOM 2540 C CA B ASP A 1 316 ? 18.844 45.592 29.799 0.50 13.71 ? 316 ASP A CA 1 ATOM 2541 C C . ASP A 1 316 ? 18.597 46.404 28.544 1.00 12.91 ? 316 ASP A C 1 ATOM 2542 O O . ASP A 1 316 ? 18.388 45.855 27.460 1.00 13.34 ? 316 ASP A O 1 ATOM 2543 C CB A ASP A 1 316 ? 17.709 45.497 30.745 0.50 13.67 ? 316 ASP A CB 1 ATOM 2544 C CB B ASP A 1 316 ? 17.550 45.748 30.613 0.50 14.54 ? 316 ASP A CB 1 ATOM 2545 C CG A ASP A 1 316 ? 16.718 44.427 30.389 0.50 15.29 ? 316 ASP A CG 1 ATOM 2546 C CG B ASP A 1 316 ? 17.448 44.817 31.798 0.50 17.13 ? 316 ASP A CG 1 ATOM 2547 O OD1 A ASP A 1 316 ? 17.124 43.364 29.887 0.50 16.71 ? 316 ASP A OD1 1 ATOM 2548 O OD1 B ASP A 1 316 ? 18.309 43.942 32.005 0.50 19.96 ? 316 ASP A OD1 1 ATOM 2549 O OD2 A ASP A 1 316 ? 15.503 44.560 30.616 0.50 18.44 ? 316 ASP A OD2 1 ATOM 2550 O OD2 B ASP A 1 316 ? 16.485 44.909 32.594 0.50 21.34 ? 316 ASP A OD2 1 ATOM 2551 N N . LEU A 1 317 ? 18.578 47.731 28.693 1.00 12.97 ? 317 LEU A N 1 ATOM 2552 C CA . LEU A 1 317 ? 18.268 48.601 27.576 1.00 12.66 ? 317 LEU A CA 1 ATOM 2553 C C . LEU A 1 317 ? 19.319 48.498 26.481 1.00 11.40 ? 317 LEU A C 1 ATOM 2554 O O . LEU A 1 317 ? 18.967 48.406 25.307 1.00 11.33 ? 317 LEU A O 1 ATOM 2555 C CB . LEU A 1 317 ? 18.167 50.070 28.020 1.00 14.10 ? 317 LEU A CB 1 ATOM 2556 C CG . LEU A 1 317 ? 16.786 50.575 28.439 1.00 17.45 ? 317 LEU A CG 1 ATOM 2557 C CD1 . LEU A 1 317 ? 16.918 51.912 29.186 1.00 21.85 ? 317 LEU A CD1 1 ATOM 2558 C CD2 . LEU A 1 317 ? 15.845 50.689 27.245 1.00 19.50 ? 317 LEU A CD2 1 ATOM 2559 N N . LEU A 1 318 ? 20.576 48.470 26.905 1.00 10.70 ? 318 LEU A N 1 ATOM 2560 C CA . LEU A 1 318 ? 21.687 48.480 25.954 1.00 9.88 ? 318 LEU A CA 1 ATOM 2561 C C . LEU A 1 318 ? 21.791 47.139 25.226 1.00 10.37 ? 318 LEU A C 1 ATOM 2562 O O . LEU A 1 318 ? 21.896 47.108 23.980 1.00 9.83 ? 318 LEU A O 1 ATOM 2563 C CB . LEU A 1 318 ? 22.991 48.855 26.647 1.00 10.17 ? 318 LEU A CB 1 ATOM 2564 C CG . LEU A 1 318 ? 24.219 48.905 25.730 1.00 11.94 ? 318 LEU A CG 1 ATOM 2565 C CD1 . LEU A 1 318 ? 24.029 49.945 24.639 1.00 11.32 ? 318 LEU A CD1 1 ATOM 2566 C CD2 . LEU A 1 318 ? 25.450 49.224 26.555 1.00 14.18 ? 318 LEU A CD2 1 ATOM 2567 N N . VAL A 1 319 ? 21.712 46.027 25.961 1.00 9.62 ? 319 VAL A N 1 ATOM 2568 C CA . VAL A 1 319 ? 21.802 44.719 25.308 1.00 9.63 ? 319 VAL A CA 1 ATOM 2569 C C . VAL A 1 319 ? 20.648 44.531 24.320 1.00 9.28 ? 319 VAL A C 1 ATOM 2570 O O . VAL A 1 319 ? 20.823 43.945 23.263 1.00 9.80 ? 319 VAL A O 1 ATOM 2571 C CB . VAL A 1 319 ? 21.826 43.589 26.344 1.00 9.74 ? 319 VAL A CB 1 ATOM 2572 C CG1 . VAL A 1 319 ? 21.654 42.217 25.648 1.00 11.70 ? 319 VAL A CG1 1 ATOM 2573 C CG2 . VAL A 1 319 ? 23.130 43.629 27.117 1.00 10.15 ? 319 VAL A CG2 1 ATOM 2574 N N . ASP A 1 320 ? 19.463 45.029 24.650 1.00 9.94 ? 320 ASP A N 1 ATOM 2575 C CA . ASP A 1 320 ? 18.338 44.976 23.735 1.00 10.08 ? 320 ASP A CA 1 ATOM 2576 C C . ASP A 1 320 ? 18.661 45.714 22.425 1.00 9.71 ? 320 ASP A C 1 ATOM 2577 O O . ASP A 1 320 ? 18.325 45.216 21.343 1.00 10.35 ? 320 ASP A O 1 ATOM 2578 C CB . ASP A 1 320 ? 17.068 45.539 24.417 1.00 11.66 ? 320 ASP A CB 1 ATOM 2579 C CG . ASP A 1 320 ? 15.907 45.631 23.496 1.00 12.43 ? 320 ASP A CG 1 ATOM 2580 O OD1 . ASP A 1 320 ? 15.370 44.547 23.124 1.00 15.46 ? 320 ASP A OD1 1 ATOM 2581 O OD2 . ASP A 1 320 ? 15.429 46.726 23.109 1.00 14.31 ? 320 ASP A OD2 1 ATOM 2582 N N . GLN A 1 321 ? 19.284 46.888 22.517 1.00 9.60 ? 321 GLN A N 1 ATOM 2583 C CA . GLN A 1 321 ? 19.679 47.584 21.278 1.00 8.23 ? 321 GLN A CA 1 ATOM 2584 C C . GLN A 1 321 ? 20.694 46.747 20.483 1.00 7.20 ? 321 GLN A C 1 ATOM 2585 O O . GLN A 1 321 ? 20.566 46.611 19.269 1.00 8.05 ? 321 GLN A O 1 ATOM 2586 C CB . GLN A 1 321 ? 20.319 48.934 21.637 1.00 7.82 ? 321 GLN A CB 1 ATOM 2587 C CG . GLN A 1 321 ? 19.313 49.992 22.066 1.00 9.35 ? 321 GLN A CG 1 ATOM 2588 C CD . GLN A 1 321 ? 18.243 50.213 20.984 1.00 10.23 ? 321 GLN A CD 1 ATOM 2589 O OE1 . GLN A 1 321 ? 18.579 50.579 19.864 1.00 11.28 ? 321 GLN A OE1 1 ATOM 2590 N NE2 . GLN A 1 321 ? 16.962 49.968 21.303 1.00 11.44 ? 321 GLN A NE2 1 ATOM 2591 N N . TRP A 1 322 ? 21.695 46.211 21.168 1.00 7.55 ? 322 TRP A N 1 ATOM 2592 C CA . TRP A 1 322 ? 22.698 45.387 20.516 1.00 8.23 ? 322 TRP A CA 1 ATOM 2593 C C . TRP A 1 322 ? 22.087 44.185 19.817 1.00 8.92 ? 322 TRP A C 1 ATOM 2594 O O . TRP A 1 322 ? 22.441 43.835 18.672 1.00 9.18 ? 322 TRP A O 1 ATOM 2595 C CB . TRP A 1 322 ? 23.692 44.900 21.546 1.00 8.59 ? 322 TRP A CB 1 ATOM 2596 C CG . TRP A 1 322 ? 24.636 45.960 22.080 1.00 7.44 ? 322 TRP A CG 1 ATOM 2597 C CD1 . TRP A 1 322 ? 24.816 47.255 21.631 1.00 9.50 ? 322 TRP A CD1 1 ATOM 2598 C CD2 . TRP A 1 322 ? 25.524 45.796 23.189 1.00 7.77 ? 322 TRP A CD2 1 ATOM 2599 N NE1 . TRP A 1 322 ? 25.786 47.876 22.392 1.00 10.44 ? 322 TRP A NE1 1 ATOM 2600 C CE2 . TRP A 1 322 ? 26.251 46.992 23.338 1.00 8.67 ? 322 TRP A CE2 1 ATOM 2601 C CE3 . TRP A 1 322 ? 25.823 44.717 24.041 1.00 9.56 ? 322 TRP A CE3 1 ATOM 2602 C CZ2 . TRP A 1 322 ? 27.207 47.162 24.336 1.00 8.96 ? 322 TRP A CZ2 1 ATOM 2603 C CZ3 . TRP A 1 322 ? 26.768 44.895 25.022 1.00 9.30 ? 322 TRP A CZ3 1 ATOM 2604 C CH2 . TRP A 1 322 ? 27.454 46.090 25.152 1.00 9.16 ? 322 TRP A CH2 1 ATOM 2605 N N . LYS A 1 323 ? 21.160 43.528 20.507 1.00 8.26 ? 323 LYS A N 1 ATOM 2606 C CA . LYS A 1 323 ? 20.550 42.337 19.903 1.00 8.83 ? 323 LYS A CA 1 ATOM 2607 C C . LYS A 1 323 ? 19.692 42.660 18.705 1.00 9.09 ? 323 LYS A C 1 ATOM 2608 O O . LYS A 1 323 ? 19.613 41.866 17.758 1.00 10.43 ? 323 LYS A O 1 ATOM 2609 C CB . LYS A 1 323 ? 19.779 41.510 20.954 1.00 9.13 ? 323 LYS A CB 1 ATOM 2610 C CG . LYS A 1 323 ? 20.754 40.764 21.887 1.00 11.04 ? 323 LYS A CG 1 ATOM 2611 C CD . LYS A 1 323 ? 20.070 39.838 22.885 1.00 11.65 ? 323 LYS A CD 1 ATOM 2612 C CE . LYS A 1 323 ? 21.090 38.978 23.602 1.00 14.30 ? 323 LYS A CE 1 ATOM 2613 N NZ . LYS A 1 323 ? 20.376 38.062 24.523 1.00 18.92 ? 323 LYS A NZ 1 ATOM 2614 N N . LYS A 1 324 ? 19.046 43.814 18.714 1.00 8.93 ? 324 LYS A N 1 ATOM 2615 C CA . LYS A 1 324 ? 18.363 44.293 17.514 1.00 8.14 ? 324 LYS A CA 1 ATOM 2616 C C . LYS A 1 324 ? 19.347 44.575 16.362 1.00 8.53 ? 324 LYS A C 1 ATOM 2617 O O . LYS A 1 324 ? 19.108 44.172 15.228 1.00 8.72 ? 324 LYS A O 1 ATOM 2618 C CB . LYS A 1 324 ? 17.539 45.540 17.838 1.00 9.05 ? 324 LYS A CB 1 ATOM 2619 C CG . LYS A 1 324 ? 16.288 45.201 18.654 1.00 9.94 ? 324 LYS A CG 1 ATOM 2620 C CD . LYS A 1 324 ? 15.647 46.440 19.180 1.00 10.20 ? 324 LYS A CD 1 ATOM 2621 C CE . LYS A 1 324 ? 14.399 46.045 19.987 1.00 12.31 ? 324 LYS A CE 1 ATOM 2622 N NZ . LYS A 1 324 ? 13.824 47.177 20.757 1.00 12.94 ? 324 LYS A NZ 1 ATOM 2623 N N . LYS A 1 325 ? 20.443 45.272 16.660 1.00 7.67 ? 325 LYS A N 1 ATOM 2624 C CA . LYS A 1 325 ? 21.430 45.545 15.610 1.00 7.42 ? 325 LYS A CA 1 ATOM 2625 C C . LYS A 1 325 ? 21.953 44.207 15.069 1.00 7.38 ? 325 LYS A C 1 ATOM 2626 O O . LYS A 1 325 ? 22.109 44.036 13.840 1.00 7.66 ? 325 LYS A O 1 ATOM 2627 C CB . LYS A 1 325 ? 22.583 46.379 16.154 1.00 7.95 ? 325 LYS A CB 1 ATOM 2628 C CG . LYS A 1 325 ? 23.482 46.943 15.038 1.00 7.51 ? 325 LYS A CG 1 ATOM 2629 C CD . LYS A 1 325 ? 24.607 47.774 15.632 1.00 8.12 ? 325 LYS A CD 1 ATOM 2630 C CE . LYS A 1 325 ? 25.281 48.560 14.510 1.00 8.42 ? 325 LYS A CE 1 ATOM 2631 N NZ . LYS A 1 325 ? 26.480 49.227 15.103 1.00 8.63 ? 325 LYS A NZ 1 ATOM 2632 N N . ALA A 1 326 ? 22.177 43.228 15.954 1.00 8.17 ? 326 ALA A N 1 ATOM 2633 C CA . ALA A 1 326 ? 22.727 41.954 15.524 1.00 8.18 ? 326 ALA A CA 1 ATOM 2634 C C . ALA A 1 326 ? 21.794 41.195 14.587 1.00 8.71 ? 326 ALA A C 1 ATOM 2635 O O . ALA A 1 326 ? 22.233 40.326 13.832 1.00 8.80 ? 326 ALA A O 1 ATOM 2636 C CB . ALA A 1 326 ? 23.034 41.092 16.736 1.00 8.66 ? 326 ALA A CB 1 ATOM 2637 N N . GLU A 1 327 ? 20.503 41.474 14.678 1.00 8.89 ? 327 GLU A N 1 ATOM 2638 C CA . GLU A 1 327 ? 19.549 40.832 13.765 1.00 10.43 ? 327 GLU A CA 1 ATOM 2639 C C . GLU A 1 327 ? 19.802 41.154 12.307 1.00 9.86 ? 327 GLU A C 1 ATOM 2640 O O . GLU A 1 327 ? 19.347 40.429 11.396 1.00 11.48 ? 327 GLU A O 1 ATOM 2641 C CB . GLU A 1 327 ? 18.134 41.270 14.085 1.00 11.65 ? 327 GLU A CB 1 ATOM 2642 C CG . GLU A 1 327 ? 17.509 40.466 15.189 1.00 16.63 ? 327 GLU A CG 1 ATOM 2643 C CD . GLU A 1 327 ? 17.513 38.966 14.897 1.00 18.02 ? 327 GLU A CD 1 ATOM 2644 O OE1 . GLU A 1 327 ? 16.865 38.504 13.936 1.00 20.81 ? 327 GLU A OE1 1 ATOM 2645 O OE2 . GLU A 1 327 ? 18.163 38.230 15.633 1.00 20.09 ? 327 GLU A OE2 1 ATOM 2646 N N . LEU A 1 328 ? 20.545 42.234 12.055 1.00 8.82 ? 328 LEU A N 1 ATOM 2647 C CA . LEU A 1 328 ? 20.744 42.691 10.690 1.00 9.28 ? 328 LEU A CA 1 ATOM 2648 C C . LEU A 1 328 ? 21.958 42.039 10.053 1.00 8.98 ? 328 LEU A C 1 ATOM 2649 O O . LEU A 1 328 ? 22.241 42.278 8.861 1.00 10.40 ? 328 LEU A O 1 ATOM 2650 C CB . LEU A 1 328 ? 20.945 44.198 10.716 1.00 8.91 ? 328 LEU A CB 1 ATOM 2651 C CG . LEU A 1 328 ? 19.829 45.002 11.371 1.00 9.44 ? 328 LEU A CG 1 ATOM 2652 C CD1 . LEU A 1 328 ? 20.072 46.524 11.241 1.00 8.47 ? 328 LEU A CD1 1 ATOM 2653 C CD2 . LEU A 1 328 ? 18.443 44.643 10.805 1.00 10.51 ? 328 LEU A CD2 1 ATOM 2654 N N . TYR A 1 329 ? 22.681 41.227 10.810 1.00 8.07 ? 329 TYR A N 1 ATOM 2655 C CA . TYR A 1 329 ? 23.923 40.619 10.326 1.00 7.24 ? 329 TYR A CA 1 ATOM 2656 C C . TYR A 1 329 ? 23.930 39.130 10.534 1.00 9.43 ? 329 TYR A C 1 ATOM 2657 O O . TYR A 1 329 ? 23.083 38.619 11.280 1.00 10.80 ? 329 TYR A O 1 ATOM 2658 C CB . TYR A 1 329 ? 25.155 41.231 11.039 1.00 8.72 ? 329 TYR A CB 1 ATOM 2659 C CG . TYR A 1 329 ? 25.343 42.700 10.689 1.00 7.00 ? 329 TYR A CG 1 ATOM 2660 C CD1 . TYR A 1 329 ? 26.096 43.078 9.612 1.00 8.50 ? 329 TYR A CD1 1 ATOM 2661 C CD2 . TYR A 1 329 ? 24.732 43.691 11.448 1.00 8.16 ? 329 TYR A CD2 1 ATOM 2662 C CE1 . TYR A 1 329 ? 26.232 44.428 9.258 1.00 7.70 ? 329 TYR A CE1 1 ATOM 2663 C CE2 . TYR A 1 329 ? 24.861 45.043 11.120 1.00 8.76 ? 329 TYR A CE2 1 ATOM 2664 C CZ . TYR A 1 329 ? 25.613 45.396 10.011 1.00 8.56 ? 329 TYR A CZ 1 ATOM 2665 O OH . TYR A 1 329 ? 25.741 46.753 9.674 1.00 10.01 ? 329 TYR A OH 1 ATOM 2666 N N . ARG A 1 330 ? 24.875 38.439 9.919 1.00 9.07 ? 330 ARG A N 1 ATOM 2667 C CA . ARG A 1 330 ? 24.796 36.985 9.830 1.00 8.75 ? 330 ARG A CA 1 ATOM 2668 C C . ARG A 1 330 ? 25.562 36.217 10.876 1.00 10.36 ? 330 ARG A C 1 ATOM 2669 O O . ARG A 1 330 ? 25.343 34.998 10.989 1.00 12.52 ? 330 ARG A O 1 ATOM 2670 C CB . ARG A 1 330 ? 25.233 36.473 8.447 1.00 9.55 ? 330 ARG A CB 1 ATOM 2671 C CG . ARG A 1 330 ? 24.308 36.908 7.356 1.00 9.67 ? 330 ARG A CG 1 ATOM 2672 C CD . ARG A 1 330 ? 24.667 36.398 6.001 1.00 10.72 ? 330 ARG A CD 1 ATOM 2673 N NE . ARG A 1 330 ? 23.700 36.934 5.056 1.00 11.61 ? 330 ARG A NE 1 ATOM 2674 C CZ . ARG A 1 330 ? 23.344 36.385 3.896 1.00 13.06 ? 330 ARG A CZ 1 ATOM 2675 N NH1 . ARG A 1 330 ? 23.920 35.271 3.453 1.00 13.42 ? 330 ARG A NH1 1 ATOM 2676 N NH2 . ARG A 1 330 ? 22.433 37.011 3.155 1.00 13.42 ? 330 ARG A NH2 1 ATOM 2677 N N . THR A 1 331 ? 26.518 36.845 11.553 1.00 10.02 ? 331 THR A N 1 ATOM 2678 C CA . THR A 1 331 ? 27.313 36.101 12.549 1.00 9.95 ? 331 THR A CA 1 ATOM 2679 C C . THR A 1 331 ? 26.924 36.508 13.959 1.00 9.99 ? 331 THR A C 1 ATOM 2680 O O . THR A 1 331 ? 26.102 37.383 14.141 1.00 13.06 ? 331 THR A O 1 ATOM 2681 C CB . THR A 1 331 ? 28.826 36.301 12.384 1.00 10.42 ? 331 THR A CB 1 ATOM 2682 O OG1 . THR A 1 331 ? 29.182 37.639 12.826 1.00 10.40 ? 331 THR A OG1 1 ATOM 2683 C CG2 . THR A 1 331 ? 29.288 36.141 10.873 1.00 11.45 ? 331 THR A CG2 1 ATOM 2684 N N . ASN A 1 332 ? 27.557 35.858 14.938 1.00 10.40 ? 332 ASN A N 1 ATOM 2685 C CA . ASN A 1 332 ? 27.344 36.230 16.328 1.00 10.30 ? 332 ASN A CA 1 ATOM 2686 C C . ASN A 1 332 ? 28.411 37.178 16.844 1.00 10.35 ? 332 ASN A C 1 ATOM 2687 O O . ASN A 1 332 ? 28.698 37.209 18.043 1.00 10.34 ? 332 ASN A O 1 ATOM 2688 C CB . ASN A 1 332 ? 27.299 34.990 17.237 1.00 10.92 ? 332 ASN A CB 1 ATOM 2689 C CG . ASN A 1 332 ? 28.642 34.272 17.337 1.00 14.14 ? 332 ASN A CG 1 ATOM 2690 O OD1 . ASN A 1 332 ? 29.429 34.248 16.410 1.00 14.41 ? 332 ASN A OD1 1 ATOM 2691 N ND2 . ASN A 1 332 ? 28.895 33.654 18.494 1.00 18.04 ? 332 ASN A ND2 1 ATOM 2692 N N . VAL A 1 333 ? 28.996 37.971 15.942 1.00 9.11 ? 333 VAL A N 1 ATOM 2693 C CA . VAL A 1 333 ? 30.020 38.938 16.314 1.00 9.17 ? 333 VAL A CA 1 ATOM 2694 C C . VAL A 1 333 ? 29.468 40.282 15.880 1.00 7.99 ? 333 VAL A C 1 ATOM 2695 O O . VAL A 1 333 ? 29.124 40.455 14.709 1.00 8.97 ? 333 VAL A O 1 ATOM 2696 C CB . VAL A 1 333 ? 31.330 38.673 15.562 1.00 9.37 ? 333 VAL A CB 1 ATOM 2697 C CG1 . VAL A 1 333 ? 32.404 39.661 15.999 1.00 9.55 ? 333 VAL A CG1 1 ATOM 2698 C CG2 . VAL A 1 333 ? 31.798 37.240 15.802 1.00 10.83 ? 333 VAL A CG2 1 ATOM 2699 N N . LEU A 1 334 ? 29.381 41.242 16.811 1.00 7.74 ? 334 LEU A N 1 ATOM 2700 C CA . LEU A 1 334 ? 28.746 42.527 16.569 1.00 7.28 ? 334 LEU A CA 1 ATOM 2701 C C . LEU A 1 334 ? 29.733 43.683 16.716 1.00 6.12 ? 334 LEU A C 1 ATOM 2702 O O . LEU A 1 334 ? 30.427 43.805 17.725 1.00 7.39 ? 334 LEU A O 1 ATOM 2703 C CB . LEU A 1 334 ? 27.594 42.720 17.569 1.00 6.68 ? 334 LEU A CB 1 ATOM 2704 C CG . LEU A 1 334 ? 26.742 43.969 17.359 1.00 8.03 ? 334 LEU A CG 1 ATOM 2705 C CD1 . LEU A 1 334 ? 25.984 43.898 16.048 1.00 7.83 ? 334 LEU A CD1 1 ATOM 2706 C CD2 . LEU A 1 334 ? 25.778 44.089 18.522 1.00 8.31 ? 334 LEU A CD2 1 ATOM 2707 N N . LEU A 1 335 ? 29.725 44.588 15.725 1.00 6.64 ? 335 LEU A N 1 ATOM 2708 C CA . LEU A 1 335 ? 30.531 45.805 15.777 1.00 6.11 ? 335 LEU A CA 1 ATOM 2709 C C . LEU A 1 335 ? 29.722 46.971 16.314 1.00 5.44 ? 335 LEU A C 1 ATOM 2710 O O . LEU A 1 335 ? 28.691 47.309 15.740 1.00 6.66 ? 335 LEU A O 1 ATOM 2711 C CB . LEU A 1 335 ? 31.012 46.136 14.348 1.00 7.30 ? 335 LEU A CB 1 ATOM 2712 C CG . LEU A 1 335 ? 31.886 47.362 14.241 1.00 6.26 ? 335 LEU A CG 1 ATOM 2713 C CD1 . LEU A 1 335 ? 33.204 47.204 14.959 1.00 9.67 ? 335 LEU A CD1 1 ATOM 2714 C CD2 . LEU A 1 335 ? 32.129 47.717 12.796 1.00 10.10 ? 335 LEU A CD2 1 ATOM 2715 N N . ILE A 1 336 ? 30.221 47.606 17.389 1.00 5.48 ? 336 ILE A N 1 ATOM 2716 C CA . ILE A 1 336 ? 29.624 48.811 17.954 1.00 6.15 ? 336 ILE A CA 1 ATOM 2717 C C . ILE A 1 336 ? 30.664 49.928 17.983 1.00 5.51 ? 336 ILE A C 1 ATOM 2718 O O . ILE A 1 336 ? 31.428 50.052 18.928 1.00 6.97 ? 336 ILE A O 1 ATOM 2719 C CB . ILE A 1 336 ? 29.084 48.549 19.376 1.00 6.95 ? 336 ILE A CB 1 ATOM 2720 C CG1 . ILE A 1 336 ? 28.068 47.390 19.393 1.00 7.16 ? 336 ILE A CG1 1 ATOM 2721 C CG2 . ILE A 1 336 ? 28.519 49.841 19.942 1.00 7.45 ? 336 ILE A CG2 1 ATOM 2722 C CD1 . ILE A 1 336 ? 26.805 47.641 18.648 1.00 8.10 ? 336 ILE A CD1 1 ATOM 2723 N N . PRO A 1 337 ? 30.707 50.749 16.942 1.00 6.08 ? 337 PRO A N 1 ATOM 2724 C CA . PRO A 1 337 ? 31.572 51.930 17.012 1.00 6.66 ? 337 PRO A CA 1 ATOM 2725 C C . PRO A 1 337 ? 31.186 52.845 18.180 1.00 7.06 ? 337 PRO A C 1 ATOM 2726 O O . PRO A 1 337 ? 29.976 52.972 18.471 1.00 8.12 ? 337 PRO A O 1 ATOM 2727 C CB . PRO A 1 337 ? 31.330 52.610 15.658 1.00 7.25 ? 337 PRO A CB 1 ATOM 2728 C CG . PRO A 1 337 ? 30.901 51.465 14.781 1.00 7.58 ? 337 PRO A CG 1 ATOM 2729 C CD . PRO A 1 337 ? 29.972 50.672 15.662 1.00 7.44 ? 337 PRO A CD 1 ATOM 2730 N N . LEU A 1 338 ? 32.175 53.473 18.817 1.00 5.68 ? 338 LEU A N 1 ATOM 2731 C CA . LEU A 1 338 ? 31.887 54.399 19.921 1.00 5.66 ? 338 LEU A CA 1 ATOM 2732 C C . LEU A 1 338 ? 32.700 55.672 19.697 1.00 6.11 ? 338 LEU A C 1 ATOM 2733 O O . LEU A 1 338 ? 33.843 55.779 20.117 1.00 5.79 ? 338 LEU A O 1 ATOM 2734 C CB . LEU A 1 338 ? 32.227 53.746 21.281 1.00 6.12 ? 338 LEU A CB 1 ATOM 2735 C CG . LEU A 1 338 ? 31.873 54.618 22.486 1.00 7.80 ? 338 LEU A CG 1 ATOM 2736 C CD1 . LEU A 1 338 ? 30.386 54.447 22.748 1.00 8.76 ? 338 LEU A CD1 1 ATOM 2737 C CD2 . LEU A 1 338 ? 32.645 54.111 23.704 1.00 9.10 ? 338 LEU A CD2 1 ATOM 2738 N N . GLY A 1 339 ? 32.094 56.639 19.029 1.00 6.76 ? 339 GLY A N 1 ATOM 2739 C CA . GLY A 1 339 ? 32.849 57.858 18.739 1.00 7.16 ? 339 GLY A CA 1 ATOM 2740 C C . GLY A 1 339 ? 32.015 58.845 17.956 1.00 6.69 ? 339 GLY A C 1 ATOM 2741 O O . GLY A 1 339 ? 30.848 58.594 17.669 1.00 7.50 ? 339 GLY A O 1 ATOM 2742 N N . ASP A 1 340 ? 32.649 59.956 17.553 1.00 6.26 ? 340 ASP A N 1 ATOM 2743 C CA . ASP A 1 340 ? 32.023 61.045 16.847 1.00 6.62 ? 340 ASP A CA 1 ATOM 2744 C C . ASP A 1 340 ? 33.207 61.984 16.519 1.00 6.03 ? 340 ASP A C 1 ATOM 2745 O O . ASP A 1 340 ? 34.388 61.671 16.716 1.00 6.61 ? 340 ASP A O 1 ATOM 2746 C CB . ASP A 1 340 ? 30.973 61.698 17.777 1.00 6.88 ? 340 ASP A CB 1 ATOM 2747 C CG . ASP A 1 340 ? 29.890 62.472 17.055 1.00 8.82 ? 340 ASP A CG 1 ATOM 2748 O OD1 . ASP A 1 340 ? 30.075 62.827 15.849 1.00 10.11 ? 340 ASP A OD1 1 ATOM 2749 O OD2 . ASP A 1 340 ? 28.834 62.782 17.704 1.00 9.71 ? 340 ASP A OD2 1 ATOM 2750 N N . ASP A 1 341 ? 32.835 63.129 15.971 1.00 6.70 ? 341 ASP A N 1 ATOM 2751 C CA . ASP A 1 341 ? 33.799 64.105 15.465 1.00 6.34 ? 341 ASP A CA 1 ATOM 2752 C C . ASP A 1 341 ? 34.673 64.662 16.577 1.00 6.66 ? 341 ASP A C 1 ATOM 2753 O O . ASP A 1 341 ? 34.165 65.168 17.587 1.00 7.00 ? 341 ASP A O 1 ATOM 2754 C CB . ASP A 1 341 ? 33.107 65.271 14.784 1.00 8.13 ? 341 ASP A CB 1 ATOM 2755 C CG . ASP A 1 341 ? 32.492 64.906 13.468 1.00 10.28 ? 341 ASP A CG 1 ATOM 2756 O OD1 . ASP A 1 341 ? 32.458 63.738 13.068 1.00 9.97 ? 341 ASP A OD1 1 ATOM 2757 O OD2 . ASP A 1 341 ? 32.081 65.807 12.715 1.00 13.90 ? 341 ASP A OD2 1 ATOM 2758 N N . PHE A 1 342 ? 35.981 64.587 16.389 1.00 6.13 ? 342 PHE A N 1 ATOM 2759 C CA . PHE A 1 342 ? 36.932 65.141 17.345 1.00 6.42 ? 342 PHE A CA 1 ATOM 2760 C C . PHE A 1 342 ? 36.632 64.732 18.795 1.00 6.46 ? 342 PHE A C 1 ATOM 2761 O O . PHE A 1 342 ? 36.848 65.505 19.753 1.00 8.83 ? 342 PHE A O 1 ATOM 2762 C CB . PHE A 1 342 ? 37.057 66.667 17.160 1.00 7.25 ? 342 PHE A CB 1 ATOM 2763 C CG . PHE A 1 342 ? 37.673 67.049 15.842 1.00 6.85 ? 342 PHE A CG 1 ATOM 2764 C CD1 . PHE A 1 342 ? 39.041 66.977 15.647 1.00 6.56 ? 342 PHE A CD1 1 ATOM 2765 C CD2 . PHE A 1 342 ? 36.863 67.465 14.785 1.00 7.73 ? 342 PHE A CD2 1 ATOM 2766 C CE1 . PHE A 1 342 ? 39.586 67.329 14.423 1.00 7.18 ? 342 PHE A CE1 1 ATOM 2767 C CE2 . PHE A 1 342 ? 37.417 67.800 13.538 1.00 7.57 ? 342 PHE A CE2 1 ATOM 2768 C CZ . PHE A 1 342 ? 38.769 67.728 13.377 1.00 7.23 ? 342 PHE A CZ 1 ATOM 2769 N N . ARG A 1 343 ? 36.229 63.476 18.957 1.00 6.57 ? 343 ARG A N 1 ATOM 2770 C CA . ARG A 1 343 ? 36.000 62.956 20.308 1.00 6.87 ? 343 ARG A CA 1 ATOM 2771 C C . ARG A 1 343 ? 37.293 62.495 20.972 1.00 8.08 ? 343 ARG A C 1 ATOM 2772 O O . ARG A 1 343 ? 38.362 62.401 20.367 1.00 7.37 ? 343 ARG A O 1 ATOM 2773 C CB . ARG A 1 343 ? 35.000 61.810 20.246 1.00 6.58 ? 343 ARG A CB 1 ATOM 2774 C CG . ARG A 1 343 ? 33.570 62.285 20.023 1.00 7.01 ? 343 ARG A CG 1 ATOM 2775 C CD . ARG A 1 343 ? 33.085 63.200 21.124 1.00 7.01 ? 343 ARG A CD 1 ATOM 2776 N NE . ARG A 1 343 ? 31.641 63.452 21.025 1.00 7.47 ? 343 ARG A NE 1 ATOM 2777 C CZ . ARG A 1 343 ? 30.723 62.747 21.671 1.00 7.46 ? 343 ARG A CZ 1 ATOM 2778 N NH1 . ARG A 1 343 ? 31.069 61.692 22.419 1.00 6.73 ? 343 ARG A NH1 1 ATOM 2779 N NH2 . ARG A 1 343 ? 29.447 63.101 21.535 1.00 7.66 ? 343 ARG A NH2 1 ATOM 2780 N N . PHE A 1 344 ? 37.183 62.223 22.274 1.00 8.20 ? 344 PHE A N 1 ATOM 2781 C CA . PHE A 1 344 ? 38.314 61.712 23.091 1.00 8.66 ? 344 PHE A CA 1 ATOM 2782 C C . PHE A 1 344 ? 39.401 62.747 23.227 1.00 9.82 ? 344 PHE A C 1 ATOM 2783 O O . PHE A 1 344 ? 40.580 62.449 23.167 1.00 10.89 ? 344 PHE A O 1 ATOM 2784 C CB . PHE A 1 344 ? 38.745 60.333 22.577 1.00 9.65 ? 344 PHE A CB 1 ATOM 2785 C CG . PHE A 1 344 ? 37.699 59.304 22.783 1.00 8.20 ? 344 PHE A CG 1 ATOM 2786 C CD1 . PHE A 1 344 ? 37.486 58.771 24.062 1.00 10.00 ? 344 PHE A CD1 1 ATOM 2787 C CD2 . PHE A 1 344 ? 36.883 58.895 21.743 1.00 9.60 ? 344 PHE A CD2 1 ATOM 2788 C CE1 . PHE A 1 344 ? 36.492 57.823 24.267 1.00 11.17 ? 344 PHE A CE1 1 ATOM 2789 C CE2 . PHE A 1 344 ? 35.886 57.970 21.940 1.00 9.27 ? 344 PHE A CE2 1 ATOM 2790 C CZ . PHE A 1 344 ? 35.695 57.437 23.215 1.00 10.18 ? 344 PHE A CZ 1 ATOM 2791 N N A LYS A 1 345 ? 38.958 63.978 23.415 0.50 10.66 ? 345 LYS A N 1 ATOM 2792 N N B LYS A 1 345 ? 38.990 63.985 23.484 0.50 10.84 ? 345 LYS A N 1 ATOM 2793 C CA A LYS A 1 345 ? 39.833 65.098 23.649 0.50 11.31 ? 345 LYS A CA 1 ATOM 2794 C CA B LYS A 1 345 ? 39.900 65.126 23.545 0.50 11.86 ? 345 LYS A CA 1 ATOM 2795 C C A LYS A 1 345 ? 40.117 65.147 25.166 0.50 11.21 ? 345 LYS A C 1 ATOM 2796 C C B LYS A 1 345 ? 40.400 65.452 24.927 0.50 12.07 ? 345 LYS A C 1 ATOM 2797 O O A LYS A 1 345 ? 41.171 64.681 25.614 0.50 10.90 ? 345 LYS A O 1 ATOM 2798 O O B LYS A 1 345 ? 41.537 65.864 25.112 0.50 11.49 ? 345 LYS A O 1 ATOM 2799 C CB . LYS A 1 345 ? 39.202 66.379 23.061 1.00 12.46 ? 345 LYS A CB 1 ATOM 2800 C CG . LYS A 1 345 ? 40.096 67.607 23.063 1.00 14.25 ? 345 LYS A CG 1 ATOM 2801 C CD . LYS A 1 345 ? 39.309 68.810 22.596 1.00 18.45 ? 345 LYS A CD 1 ATOM 2802 C CE . LYS A 1 345 ? 40.034 70.095 22.840 1.00 21.93 ? 345 LYS A CE 1 ATOM 2803 N NZ . LYS A 1 345 ? 39.268 71.199 22.186 1.00 24.07 ? 345 LYS A NZ 1 ATOM 2804 N N A GLN A 1 346 ? 39.146 65.632 25.941 0.50 11.28 ? 346 GLN A N 1 ATOM 2805 N N B GLN A 1 346 ? 39.499 65.337 25.882 0.50 13.01 ? 346 GLN A N 1 ATOM 2806 C CA A GLN A 1 346 ? 39.331 65.830 27.391 0.50 11.17 ? 346 GLN A CA 1 ATOM 2807 C CA B GLN A 1 346 ? 39.799 65.750 27.229 0.50 13.29 ? 346 GLN A CA 1 ATOM 2808 C C A GLN A 1 346 ? 39.719 64.547 28.162 0.50 11.86 ? 346 GLN A C 1 ATOM 2809 C C B GLN A 1 346 ? 39.828 64.539 28.101 0.50 13.15 ? 346 GLN A C 1 ATOM 2810 O O A GLN A 1 346 ? 39.150 63.492 27.899 0.50 10.57 ? 346 GLN A O 1 ATOM 2811 O O B GLN A 1 346 ? 39.102 63.570 27.886 0.50 11.80 ? 346 GLN A O 1 ATOM 2812 C CB A GLN A 1 346 ? 38.038 66.425 27.972 0.50 11.27 ? 346 GLN A CB 1 ATOM 2813 C CB B GLN A 1 346 ? 38.737 66.706 27.738 0.50 14.46 ? 346 GLN A CB 1 ATOM 2814 C CG A GLN A 1 346 ? 37.642 67.758 27.343 0.50 11.06 ? 346 GLN A CG 1 ATOM 2815 C CG B GLN A 1 346 ? 39.013 68.146 27.441 0.50 16.47 ? 346 GLN A CG 1 ATOM 2816 C CD A GLN A 1 346 ? 36.565 67.637 26.273 0.50 12.94 ? 346 GLN A CD 1 ATOM 2817 C CD B GLN A 1 346 ? 38.022 69.054 28.125 0.50 19.35 ? 346 GLN A CD 1 ATOM 2818 O OE1 A GLN A 1 346 ? 36.368 66.577 25.671 0.50 8.43 ? 346 GLN A OE1 1 ATOM 2819 O OE1 B GLN A 1 346 ? 38.398 69.857 28.984 0.50 22.39 ? 346 GLN A OE1 1 ATOM 2820 N NE2 A GLN A 1 346 ? 35.840 68.716 26.062 0.50 14.33 ? 346 GLN A NE2 1 ATOM 2821 N NE2 B GLN A 1 346 ? 36.751 68.929 27.757 0.50 20.65 ? 346 GLN A NE2 1 ATOM 2822 N N . ASN A 1 347 ? 40.668 64.619 29.116 1.00 12.84 ? 347 ASN A N 1 ATOM 2823 C CA . ASN A 1 347 ? 40.865 63.527 30.060 1.00 12.58 ? 347 ASN A CA 1 ATOM 2824 C C . ASN A 1 347 ? 39.575 63.087 30.719 1.00 11.77 ? 347 ASN A C 1 ATOM 2825 O O . ASN A 1 347 ? 39.333 61.879 30.844 1.00 11.19 ? 347 ASN A O 1 ATOM 2826 C CB . ASN A 1 347 ? 41.839 63.947 31.160 1.00 13.50 ? 347 ASN A CB 1 ATOM 2827 C CG . ASN A 1 347 ? 43.216 64.095 30.642 1.00 16.98 ? 347 ASN A CG 1 ATOM 2828 O OD1 . ASN A 1 347 ? 43.688 63.245 29.897 1.00 19.47 ? 347 ASN A OD1 1 ATOM 2829 N ND2 . ASN A 1 347 ? 43.879 65.203 31.002 1.00 22.23 ? 347 ASN A ND2 1 ATOM 2830 N N . THR A 1 348 ? 38.739 64.052 31.090 1.00 11.22 ? 348 THR A N 1 ATOM 2831 C CA . THR A 1 348 ? 37.468 63.735 31.734 1.00 12.03 ? 348 THR A CA 1 ATOM 2832 C C . THR A 1 348 ? 36.547 62.974 30.800 1.00 12.17 ? 348 THR A C 1 ATOM 2833 O O . THR A 1 348 ? 35.735 62.186 31.261 1.00 10.99 ? 348 THR A O 1 ATOM 2834 C CB . THR A 1 348 ? 36.760 64.993 32.251 1.00 13.33 ? 348 THR A CB 1 ATOM 2835 O OG1 . THR A 1 348 ? 36.719 65.969 31.212 1.00 15.34 ? 348 THR A OG1 1 ATOM 2836 C CG2 . THR A 1 348 ? 37.606 65.640 33.351 1.00 13.89 ? 348 THR A CG2 1 ATOM 2837 N N . GLU A 1 349 ? 36.673 63.205 29.488 1.00 9.25 ? 349 GLU A N 1 ATOM 2838 C CA . GLU A 1 349 ? 35.863 62.489 28.510 1.00 9.23 ? 349 GLU A CA 1 ATOM 2839 C C . GLU A 1 349 ? 36.347 61.041 28.370 1.00 8.09 ? 349 GLU A C 1 ATOM 2840 O O . GLU A 1 349 ? 35.550 60.113 28.346 1.00 8.32 ? 349 GLU A O 1 ATOM 2841 C CB . GLU A 1 349 ? 35.971 63.192 27.150 1.00 8.84 ? 349 GLU A CB 1 ATOM 2842 C CG . GLU A 1 349 ? 35.254 62.424 26.072 1.00 11.20 ? 349 GLU A CG 1 ATOM 2843 C CD . GLU A 1 349 ? 35.470 63.017 24.687 1.00 10.35 ? 349 GLU A CD 1 ATOM 2844 O OE1 . GLU A 1 349 ? 36.156 64.049 24.534 1.00 11.70 ? 349 GLU A OE1 1 ATOM 2845 O OE2 . GLU A 1 349 ? 34.932 62.408 23.763 1.00 10.79 ? 349 GLU A OE2 1 ATOM 2846 N N . TRP A 1 350 ? 37.657 60.835 28.311 1.00 8.89 ? 350 TRP A N 1 ATOM 2847 C CA . TRP A 1 350 ? 38.170 59.461 28.343 1.00 9.55 ? 350 TRP A CA 1 ATOM 2848 C C . TRP A 1 350 ? 37.622 58.697 29.545 1.00 9.56 ? 350 TRP A C 1 ATOM 2849 O O . TRP A 1 350 ? 37.123 57.600 29.436 1.00 9.70 ? 350 TRP A O 1 ATOM 2850 C CB . TRP A 1 350 ? 39.691 59.425 28.381 1.00 9.00 ? 350 TRP A CB 1 ATOM 2851 C CG . TRP A 1 350 ? 40.321 59.658 27.015 1.00 8.62 ? 350 TRP A CG 1 ATOM 2852 C CD1 . TRP A 1 350 ? 40.657 60.860 26.461 1.00 9.02 ? 350 TRP A CD1 1 ATOM 2853 C CD2 . TRP A 1 350 ? 40.620 58.654 26.038 1.00 8.69 ? 350 TRP A CD2 1 ATOM 2854 N NE1 . TRP A 1 350 ? 41.197 60.655 25.209 1.00 8.77 ? 350 TRP A NE1 1 ATOM 2855 C CE2 . TRP A 1 350 ? 41.177 59.318 24.921 1.00 8.52 ? 350 TRP A CE2 1 ATOM 2856 C CE3 . TRP A 1 350 ? 40.511 57.270 26.006 1.00 12.68 ? 350 TRP A CE3 1 ATOM 2857 C CZ2 . TRP A 1 350 ? 41.588 58.639 23.781 1.00 12.91 ? 350 TRP A CZ2 1 ATOM 2858 C CZ3 . TRP A 1 350 ? 40.933 56.600 24.865 1.00 13.17 ? 350 TRP A CZ3 1 ATOM 2859 C CH2 . TRP A 1 350 ? 41.446 57.289 23.772 1.00 12.47 ? 350 TRP A CH2 1 ATOM 2860 N N . ASP A 1 351 ? 37.672 59.335 30.709 1.00 10.27 ? 351 ASP A N 1 ATOM 2861 C CA . ASP A 1 351 ? 37.213 58.660 31.918 1.00 10.94 ? 351 ASP A CA 1 ATOM 2862 C C . ASP A 1 351 ? 35.731 58.388 31.895 1.00 10.69 ? 351 ASP A C 1 ATOM 2863 O O . ASP A 1 351 ? 35.311 57.289 32.280 1.00 10.53 ? 351 ASP A O 1 ATOM 2864 C CB . ASP A 1 351 ? 37.493 59.497 33.160 1.00 12.27 ? 351 ASP A CB 1 ATOM 2865 C CG . ASP A 1 351 ? 38.956 59.585 33.511 1.00 17.82 ? 351 ASP A CG 1 ATOM 2866 O OD1 . ASP A 1 351 ? 39.736 58.688 33.149 1.00 20.69 ? 351 ASP A OD1 1 ATOM 2867 O OD2 . ASP A 1 351 ? 39.416 60.530 34.205 1.00 24.65 ? 351 ASP A OD2 1 ATOM 2868 N N . VAL A 1 352 ? 34.931 59.368 31.474 1.00 10.21 ? 352 VAL A N 1 ATOM 2869 C CA . VAL A 1 352 ? 33.509 59.193 31.578 1.00 11.22 ? 352 VAL A CA 1 ATOM 2870 C C . VAL A 1 352 ? 33.049 58.070 30.626 1.00 10.73 ? 352 VAL A C 1 ATOM 2871 O O . VAL A 1 352 ? 32.172 57.261 30.980 1.00 12.14 ? 352 VAL A O 1 ATOM 2872 C CB . VAL A 1 352 ? 32.733 60.528 31.420 1.00 12.91 ? 352 VAL A CB 1 ATOM 2873 C CG1 . VAL A 1 352 ? 32.646 60.944 29.978 1.00 13.43 ? 352 VAL A CG1 1 ATOM 2874 C CG2 . VAL A 1 352 ? 31.363 60.453 32.057 1.00 15.53 ? 352 VAL A CG2 1 ATOM 2875 N N . GLN A 1 353 ? 33.662 57.945 29.447 1.00 9.64 ? 353 GLN A N 1 ATOM 2876 C CA . GLN A 1 353 ? 33.245 56.884 28.539 1.00 9.11 ? 353 GLN A CA 1 ATOM 2877 C C . GLN A 1 353 ? 33.779 55.539 29.020 1.00 9.08 ? 353 GLN A C 1 ATOM 2878 O O . GLN A 1 353 ? 33.016 54.578 29.115 1.00 9.65 ? 353 GLN A O 1 ATOM 2879 C CB . GLN A 1 353 ? 33.740 57.167 27.103 1.00 8.21 ? 353 GLN A CB 1 ATOM 2880 C CG . GLN A 1 353 ? 33.196 58.473 26.456 1.00 9.91 ? 353 GLN A CG 1 ATOM 2881 C CD . GLN A 1 353 ? 31.743 58.390 25.997 1.00 9.85 ? 353 GLN A CD 1 ATOM 2882 O OE1 . GLN A 1 353 ? 30.927 57.652 26.561 1.00 8.41 ? 353 GLN A OE1 1 ATOM 2883 N NE2 . GLN A 1 353 ? 31.403 59.147 24.969 1.00 8.48 ? 353 GLN A NE2 1 ATOM 2884 N N . ARG A 1 354 ? 35.066 55.472 29.355 1.00 8.44 ? 354 ARG A N 1 ATOM 2885 C CA . ARG A 1 354 ? 35.644 54.194 29.782 1.00 9.12 ? 354 ARG A CA 1 ATOM 2886 C C . ARG A 1 354 ? 35.005 53.637 31.044 1.00 9.97 ? 354 ARG A C 1 ATOM 2887 O O . ARG A 1 354 ? 34.673 52.465 31.092 1.00 10.47 ? 354 ARG A O 1 ATOM 2888 C CB . ARG A 1 354 ? 37.137 54.329 30.008 1.00 10.02 ? 354 ARG A CB 1 ATOM 2889 C CG . ARG A 1 354 ? 37.797 53.037 30.455 1.00 10.11 ? 354 ARG A CG 1 ATOM 2890 C CD . ARG A 1 354 ? 39.289 53.191 30.756 1.00 11.53 ? 354 ARG A CD 1 ATOM 2891 N NE . ARG A 1 354 ? 39.536 54.266 31.718 1.00 12.74 ? 354 ARG A NE 1 ATOM 2892 C CZ . ARG A 1 354 ? 39.432 54.166 33.047 1.00 13.95 ? 354 ARG A CZ 1 ATOM 2893 N NH1 . ARG A 1 354 ? 39.098 53.015 33.611 1.00 14.98 ? 354 ARG A NH1 1 ATOM 2894 N NH2 . ARG A 1 354 ? 39.696 55.212 33.806 1.00 16.27 ? 354 ARG A NH2 1 ATOM 2895 N N . VAL A 1 355 ? 34.875 54.449 32.089 1.00 8.62 ? 355 VAL A N 1 ATOM 2896 C CA . VAL A 1 355 ? 34.436 53.866 33.357 1.00 10.35 ? 355 VAL A CA 1 ATOM 2897 C C . VAL A 1 355 ? 32.998 53.391 33.248 1.00 9.65 ? 355 VAL A C 1 ATOM 2898 O O . VAL A 1 355 ? 32.655 52.319 33.787 1.00 10.69 ? 355 VAL A O 1 ATOM 2899 C CB . VAL A 1 355 ? 34.641 54.866 34.513 1.00 10.62 ? 355 VAL A CB 1 ATOM 2900 C CG1 . VAL A 1 355 ? 34.022 54.371 35.844 1.00 15.02 ? 355 VAL A CG1 1 ATOM 2901 C CG2 . VAL A 1 355 ? 36.107 55.162 34.721 1.00 12.78 ? 355 VAL A CG2 1 ATOM 2902 N N . ASN A 1 356 ? 32.134 54.173 32.601 1.00 8.31 ? 356 ASN A N 1 ATOM 2903 C CA . ASN A 1 356 ? 30.750 53.769 32.452 1.00 8.92 ? 356 ASN A CA 1 ATOM 2904 C C . ASN A 1 356 ? 30.618 52.491 31.621 1.00 9.71 ? 356 ASN A C 1 ATOM 2905 O O . ASN A 1 356 ? 29.902 51.554 32.002 1.00 9.73 ? 356 ASN A O 1 ATOM 2906 C CB . ASN A 1 356 ? 29.886 54.912 31.977 1.00 8.59 ? 356 ASN A CB 1 ATOM 2907 C CG . ASN A 1 356 ? 29.664 55.920 33.048 1.00 10.58 ? 356 ASN A CG 1 ATOM 2908 O OD1 . ASN A 1 356 ? 28.973 55.617 34.026 1.00 12.16 ? 356 ASN A OD1 1 ATOM 2909 N ND2 . ASN A 1 356 ? 30.243 57.101 32.918 1.00 11.22 ? 356 ASN A ND2 1 ATOM 2910 N N . TYR A 1 357 ? 31.336 52.427 30.496 1.00 8.65 ? 357 TYR A N 1 ATOM 2911 C CA . TYR A 1 357 ? 31.339 51.179 29.721 1.00 8.82 ? 357 TYR A CA 1 ATOM 2912 C C . TYR A 1 357 ? 31.920 49.976 30.483 1.00 8.79 ? 357 TYR A C 1 ATOM 2913 O O . TYR A 1 357 ? 31.380 48.860 30.377 1.00 9.86 ? 357 TYR A O 1 ATOM 2914 C CB . TYR A 1 357 ? 31.982 51.357 28.296 1.00 8.35 ? 357 TYR A CB 1 ATOM 2915 C CG . TYR A 1 357 ? 30.960 51.872 27.320 1.00 7.37 ? 357 TYR A CG 1 ATOM 2916 C CD1 . TYR A 1 357 ? 30.133 50.986 26.626 1.00 8.87 ? 357 TYR A CD1 1 ATOM 2917 C CD2 . TYR A 1 357 ? 30.763 53.247 27.126 1.00 7.16 ? 357 TYR A CD2 1 ATOM 2918 C CE1 . TYR A 1 357 ? 29.131 51.460 25.732 1.00 8.56 ? 357 TYR A CE1 1 ATOM 2919 C CE2 . TYR A 1 357 ? 29.758 53.733 26.264 1.00 6.69 ? 357 TYR A CE2 1 ATOM 2920 C CZ . TYR A 1 357 ? 28.944 52.846 25.570 1.00 8.55 ? 357 TYR A CZ 1 ATOM 2921 O OH . TYR A 1 357 ? 27.953 53.267 24.730 1.00 9.81 ? 357 TYR A OH 1 ATOM 2922 N N . GLU A 1 358 ? 33.003 50.182 31.235 1.00 9.57 ? 358 GLU A N 1 ATOM 2923 C CA . GLU A 1 358 ? 33.566 49.084 32.042 1.00 10.34 ? 358 GLU A CA 1 ATOM 2924 C C . GLU A 1 358 ? 32.527 48.553 33.016 1.00 10.54 ? 358 GLU A C 1 ATOM 2925 O O . GLU A 1 358 ? 32.425 47.330 33.187 1.00 10.46 ? 358 GLU A O 1 ATOM 2926 C CB . GLU A 1 358 ? 34.785 49.555 32.806 1.00 10.85 ? 358 GLU A CB 1 ATOM 2927 C CG . GLU A 1 358 ? 36.062 49.700 31.988 1.00 14.66 ? 358 GLU A CG 1 ATOM 2928 C CD . GLU A 1 358 ? 37.247 50.110 32.876 1.00 13.98 ? 358 GLU A CD 1 ATOM 2929 O OE1 . GLU A 1 358 ? 37.152 50.000 34.136 1.00 22.15 ? 358 GLU A OE1 1 ATOM 2930 O OE2 . GLU A 1 358 ? 38.312 50.505 32.359 1.00 19.28 ? 358 GLU A OE2 1 ATOM 2931 N N . ARG A 1 359 ? 31.742 49.437 33.636 1.00 9.69 ? 359 ARG A N 1 ATOM 2932 C CA . ARG A 1 359 ? 30.718 48.938 34.566 1.00 10.54 ? 359 ARG A CA 1 ATOM 2933 C C . ARG A 1 359 ? 29.649 48.163 33.824 1.00 10.22 ? 359 ARG A C 1 ATOM 2934 O O . ARG A 1 359 ? 29.176 47.121 34.309 1.00 10.73 ? 359 ARG A O 1 ATOM 2935 C CB . ARG A 1 359 ? 30.060 50.081 35.318 1.00 10.78 ? 359 ARG A CB 1 ATOM 2936 C CG . ARG A 1 359 ? 30.946 50.803 36.290 1.00 14.52 ? 359 ARG A CG 1 ATOM 2937 C CD . ARG A 1 359 ? 30.217 51.999 36.868 1.00 19.23 ? 359 ARG A CD 1 ATOM 2938 N NE . ARG A 1 359 ? 31.082 52.863 37.662 1.00 22.77 ? 359 ARG A NE 1 ATOM 2939 C CZ . ARG A 1 359 ? 31.134 54.188 37.525 1.00 25.09 ? 359 ARG A CZ 1 ATOM 2940 N NH1 . ARG A 1 359 ? 30.358 54.831 36.623 1.00 22.30 ? 359 ARG A NH1 1 ATOM 2941 N NH2 . ARG A 1 359 ? 31.962 54.878 38.306 1.00 28.00 ? 359 ARG A NH2 1 ATOM 2942 N N . LEU A 1 360 ? 29.220 48.639 32.652 1.00 9.46 ? 360 LEU A N 1 ATOM 2943 C CA . LEU A 1 360 ? 28.280 47.862 31.839 1.00 8.99 ? 360 LEU A CA 1 ATOM 2944 C C . LEU A 1 360 ? 28.835 46.481 31.451 1.00 9.61 ? 360 LEU A C 1 ATOM 2945 O O . LEU A 1 360 ? 28.131 45.470 31.579 1.00 10.61 ? 360 LEU A O 1 ATOM 2946 C CB . LEU A 1 360 ? 27.881 48.657 30.587 1.00 9.59 ? 360 LEU A CB 1 ATOM 2947 C CG . LEU A 1 360 ? 27.010 49.858 30.914 1.00 10.93 ? 360 LEU A CG 1 ATOM 2948 C CD1 . LEU A 1 360 ? 27.131 50.863 29.768 1.00 11.57 ? 360 LEU A CD1 1 ATOM 2949 C CD2 . LEU A 1 360 ? 25.545 49.461 31.128 1.00 12.02 ? 360 LEU A CD2 1 ATOM 2950 N N . PHE A 1 361 ? 30.079 46.423 30.983 1.00 9.42 ? 361 PHE A N 1 ATOM 2951 C CA . PHE A 1 361 ? 30.649 45.136 30.563 1.00 9.33 ? 361 PHE A CA 1 ATOM 2952 C C . PHE A 1 361 ? 30.726 44.159 31.750 1.00 10.78 ? 361 PHE A C 1 ATOM 2953 O O . PHE A 1 361 ? 30.509 42.945 31.615 1.00 10.29 ? 361 PHE A O 1 ATOM 2954 C CB . PHE A 1 361 ? 32.073 45.305 30.023 1.00 9.65 ? 361 PHE A CB 1 ATOM 2955 C CG . PHE A 1 361 ? 32.185 46.151 28.773 1.00 9.23 ? 361 PHE A CG 1 ATOM 2956 C CD1 . PHE A 1 361 ? 31.120 46.315 27.903 1.00 8.48 ? 361 PHE A CD1 1 ATOM 2957 C CD2 . PHE A 1 361 ? 33.401 46.772 28.507 1.00 9.60 ? 361 PHE A CD2 1 ATOM 2958 C CE1 . PHE A 1 361 ? 31.273 47.110 26.736 1.00 10.10 ? 361 PHE A CE1 1 ATOM 2959 C CE2 . PHE A 1 361 ? 33.568 47.550 27.342 1.00 9.90 ? 361 PHE A CE2 1 ATOM 2960 C CZ . PHE A 1 361 ? 32.495 47.722 26.481 1.00 9.32 ? 361 PHE A CZ 1 ATOM 2961 N N . GLU A 1 362 ? 31.133 44.670 32.900 1.00 11.01 ? 362 GLU A N 1 ATOM 2962 C CA . GLU A 1 362 ? 31.304 43.772 34.045 1.00 11.55 ? 362 GLU A CA 1 ATOM 2963 C C . GLU A 1 362 ? 29.945 43.146 34.391 1.00 12.70 ? 362 GLU A C 1 ATOM 2964 O O . GLU A 1 362 ? 29.855 41.929 34.605 1.00 13.44 ? 362 GLU A O 1 ATOM 2965 C CB . GLU A 1 362 ? 31.902 44.473 35.270 1.00 13.68 ? 362 GLU A CB 1 ATOM 2966 C CG . GLU A 1 362 ? 31.935 43.506 36.455 1.00 16.38 ? 362 GLU A CG 1 ATOM 2967 C CD . GLU A 1 362 ? 32.472 44.087 37.753 1.00 24.60 ? 362 GLU A CD 1 ATOM 2968 O OE1 . GLU A 1 362 ? 32.871 45.266 37.783 1.00 29.06 ? 362 GLU A OE1 1 ATOM 2969 O OE2 . GLU A 1 362 ? 32.508 43.313 38.752 1.00 26.81 ? 362 GLU A OE2 1 ATOM 2970 N N . HIS A 1 363 ? 28.898 43.961 34.410 1.00 11.05 ? 363 HIS A N 1 ATOM 2971 C CA . HIS A 1 363 ? 27.577 43.427 34.690 1.00 12.38 ? 363 HIS A CA 1 ATOM 2972 C C . HIS A 1 363 ? 27.094 42.492 33.578 1.00 12.47 ? 363 HIS A C 1 ATOM 2973 O O . HIS A 1 363 ? 26.662 41.376 33.820 1.00 13.27 ? 363 HIS A O 1 ATOM 2974 C CB . HIS A 1 363 ? 26.575 44.535 34.937 1.00 12.00 ? 363 HIS A CB 1 ATOM 2975 C CG . HIS A 1 363 ? 25.193 44.039 35.231 1.00 14.11 ? 363 HIS A CG 1 ATOM 2976 N ND1 . HIS A 1 363 ? 24.814 43.575 36.479 1.00 18.11 ? 363 HIS A ND1 1 ATOM 2977 C CD2 . HIS A 1 363 ? 24.107 43.922 34.435 1.00 16.79 ? 363 HIS A CD2 1 ATOM 2978 C CE1 . HIS A 1 363 ? 23.547 43.202 36.432 1.00 17.66 ? 363 HIS A CE1 1 ATOM 2979 N NE2 . HIS A 1 363 ? 23.091 43.404 35.208 1.00 19.26 ? 363 HIS A NE2 1 ATOM 2980 N N . ILE A 1 364 ? 27.136 42.934 32.329 1.00 11.24 ? 364 ILE A N 1 ATOM 2981 C CA . ILE A 1 364 ? 26.604 42.138 31.230 1.00 11.16 ? 364 ILE A CA 1 ATOM 2982 C C . ILE A 1 364 ? 27.335 40.813 31.143 1.00 11.17 ? 364 ILE A C 1 ATOM 2983 O O . ILE A 1 364 ? 26.708 39.753 30.959 1.00 11.90 ? 364 ILE A O 1 ATOM 2984 C CB . ILE A 1 364 ? 26.715 42.931 29.888 1.00 10.71 ? 364 ILE A CB 1 ATOM 2985 C CG1 . ILE A 1 364 ? 25.723 44.096 29.920 1.00 10.63 ? 364 ILE A CG1 1 ATOM 2986 C CG2 . ILE A 1 364 ? 26.510 41.993 28.678 1.00 12.09 ? 364 ILE A CG2 1 ATOM 2987 C CD1 . ILE A 1 364 ? 26.033 45.253 28.935 1.00 11.97 ? 364 ILE A CD1 1 ATOM 2988 N N . ASN A 1 365 ? 28.645 40.841 31.262 1.00 10.32 ? 365 ASN A N 1 ATOM 2989 C CA . ASN A 1 365 ? 29.422 39.636 30.985 1.00 11.47 ? 365 ASN A CA 1 ATOM 2990 C C . ASN A 1 365 ? 29.265 38.571 32.093 1.00 13.54 ? 365 ASN A C 1 ATOM 2991 O O . ASN A 1 365 ? 29.552 37.395 31.888 1.00 14.52 ? 365 ASN A O 1 ATOM 2992 C CB . ASN A 1 365 ? 30.888 39.959 30.776 1.00 10.24 ? 365 ASN A CB 1 ATOM 2993 C CG . ASN A 1 365 ? 31.113 40.776 29.521 1.00 9.29 ? 365 ASN A CG 1 ATOM 2994 O OD1 . ASN A 1 365 ? 30.196 40.940 28.695 1.00 11.42 ? 365 ASN A OD1 1 ATOM 2995 N ND2 . ASN A 1 365 ? 32.328 41.266 29.386 1.00 8.82 ? 365 ASN A ND2 1 ATOM 2996 N N . SER A 1 366 ? 28.822 39.037 33.261 1.00 16.01 ? 366 SER A N 1 ATOM 2997 C CA . SER A 1 366 ? 28.706 38.180 34.461 1.00 17.83 ? 366 SER A CA 1 ATOM 2998 C C . SER A 1 366 ? 27.293 37.647 34.651 1.00 19.01 ? 366 SER A C 1 ATOM 2999 O O . SER A 1 366 ? 27.070 36.802 35.528 1.00 19.61 ? 366 SER A O 1 ATOM 3000 C CB . SER A 1 366 ? 29.126 38.956 35.714 1.00 18.42 ? 366 SER A CB 1 ATOM 3001 O OG . SER A 1 366 ? 28.119 39.894 36.056 1.00 20.89 ? 366 SER A OG 1 ATOM 3002 N N . GLN A 1 367 ? 26.346 38.132 33.854 1.00 18.39 ? 367 GLN A N 1 ATOM 3003 C CA . GLN A 1 367 ? 24.932 37.773 33.927 1.00 20.01 ? 367 GLN A CA 1 ATOM 3004 C C . GLN A 1 367 ? 24.606 36.847 32.772 1.00 19.63 ? 367 GLN A C 1 ATOM 3005 O O . GLN A 1 367 ? 24.331 37.282 31.654 1.00 18.41 ? 367 GLN A O 1 ATOM 3006 C CB . GLN A 1 367 ? 24.037 39.014 33.820 1.00 20.10 ? 367 GLN A CB 1 ATOM 3007 C CG . GLN A 1 367 ? 24.059 39.915 35.034 1.00 24.58 ? 367 GLN A CG 1 ATOM 3008 C CD . GLN A 1 367 ? 23.329 39.298 36.194 1.00 28.32 ? 367 GLN A CD 1 ATOM 3009 O OE1 . GLN A 1 367 ? 22.107 39.102 36.139 1.00 31.36 ? 367 GLN A OE1 1 ATOM 3010 N NE2 . GLN A 1 367 ? 24.069 38.981 37.249 1.00 31.27 ? 367 GLN A NE2 1 ATOM 3011 N N . ALA A 1 368 ? 24.581 35.553 33.053 1.00 19.92 ? 368 ALA A N 1 ATOM 3012 C CA . ALA A 1 368 ? 24.448 34.552 32.004 1.00 19.28 ? 368 ALA A CA 1 ATOM 3013 C C . ALA A 1 368 ? 23.212 34.729 31.135 1.00 19.20 ? 368 ALA A C 1 ATOM 3014 O O . ALA A 1 368 ? 23.250 34.382 29.943 1.00 18.69 ? 368 ALA A O 1 ATOM 3015 C CB . ALA A 1 368 ? 24.475 33.149 32.623 1.00 20.25 ? 368 ALA A CB 1 ATOM 3016 N N . HIS A 1 369 ? 22.134 35.280 31.703 1.00 18.36 ? 369 HIS A N 1 ATOM 3017 C CA . HIS A 1 369 ? 20.863 35.401 30.979 1.00 18.99 ? 369 HIS A CA 1 ATOM 3018 C C . HIS A 1 369 ? 20.973 36.258 29.703 1.00 18.09 ? 369 HIS A C 1 ATOM 3019 O O . HIS A 1 369 ? 20.185 36.099 28.757 1.00 19.18 ? 369 HIS A O 1 ATOM 3020 C CB . HIS A 1 369 ? 19.719 35.896 31.885 1.00 20.17 ? 369 HIS A CB 1 ATOM 3021 C CG . HIS A 1 369 ? 19.879 37.304 32.360 1.00 21.53 ? 369 HIS A CG 1 ATOM 3022 N ND1 . HIS A 1 369 ? 19.361 38.389 31.677 1.00 25.09 ? 369 HIS A ND1 1 ATOM 3023 C CD2 . HIS A 1 369 ? 20.478 37.804 33.462 1.00 23.48 ? 369 HIS A CD2 1 ATOM 3024 C CE1 . HIS A 1 369 ? 19.651 39.497 32.337 1.00 23.08 ? 369 HIS A CE1 1 ATOM 3025 N NE2 . HIS A 1 369 ? 20.333 39.169 33.419 1.00 25.27 ? 369 HIS A NE2 1 ATOM 3026 N N . PHE A 1 370 ? 21.949 37.161 29.682 1.00 17.49 ? 370 PHE A N 1 ATOM 3027 C CA . PHE A 1 370 ? 22.156 37.978 28.489 1.00 15.39 ? 370 PHE A CA 1 ATOM 3028 C C . PHE A 1 370 ? 22.794 37.178 27.348 1.00 14.36 ? 370 PHE A C 1 ATOM 3029 O O . PHE A 1 370 ? 22.594 37.509 26.176 1.00 13.52 ? 370 PHE A O 1 ATOM 3030 C CB . PHE A 1 370 ? 23.096 39.158 28.768 1.00 15.91 ? 370 PHE A CB 1 ATOM 3031 C CG . PHE A 1 370 ? 22.510 40.256 29.642 1.00 15.44 ? 370 PHE A CG 1 ATOM 3032 C CD1 . PHE A 1 370 ? 21.330 40.914 29.289 1.00 16.25 ? 370 PHE A CD1 1 ATOM 3033 C CD2 . PHE A 1 370 ? 23.192 40.656 30.775 1.00 17.92 ? 370 PHE A CD2 1 ATOM 3034 C CE1 . PHE A 1 370 ? 20.829 41.950 30.111 1.00 18.78 ? 370 PHE A CE1 1 ATOM 3035 C CE2 . PHE A 1 370 ? 22.704 41.675 31.582 1.00 18.98 ? 370 PHE A CE2 1 ATOM 3036 C CZ . PHE A 1 370 ? 21.530 42.321 31.237 1.00 17.18 ? 370 PHE A CZ 1 ATOM 3037 N N . ASN A 1 371 ? 23.637 36.207 27.702 1.00 13.38 ? 371 ASN A N 1 ATOM 3038 C CA . ASN A 1 371 ? 24.430 35.441 26.737 1.00 12.80 ? 371 ASN A CA 1 ATOM 3039 C C . ASN A 1 371 ? 25.207 36.356 25.803 1.00 12.10 ? 371 ASN A C 1 ATOM 3040 O O . ASN A 1 371 ? 25.249 36.147 24.583 1.00 12.24 ? 371 ASN A O 1 ATOM 3041 C CB . ASN A 1 371 ? 23.553 34.469 25.944 1.00 13.02 ? 371 ASN A CB 1 ATOM 3042 C CG . ASN A 1 371 ? 22.871 33.442 26.861 1.00 13.55 ? 371 ASN A CG 1 ATOM 3043 O OD1 . ASN A 1 371 ? 23.549 32.646 27.510 1.00 17.49 ? 371 ASN A OD1 1 ATOM 3044 N ND2 . ASN A 1 371 ? 21.562 33.503 26.932 1.00 17.40 ? 371 ASN A ND2 1 ATOM 3045 N N . VAL A 1 372 ? 25.853 37.330 26.421 1.00 10.44 ? 372 VAL A N 1 ATOM 3046 C CA . VAL A 1 372 ? 26.683 38.317 25.716 1.00 10.80 ? 372 VAL A CA 1 ATOM 3047 C C . VAL A 1 372 ? 28.072 38.345 26.326 1.00 11.26 ? 372 VAL A C 1 ATOM 3048 O O . VAL A 1 372 ? 28.219 38.263 27.570 1.00 11.94 ? 372 VAL A O 1 ATOM 3049 C CB . VAL A 1 372 ? 26.050 39.765 25.824 1.00 10.94 ? 372 VAL A CB 1 ATOM 3050 C CG1 . VAL A 1 372 ? 27.050 40.847 25.333 1.00 10.67 ? 372 VAL A CG1 1 ATOM 3051 C CG2 . VAL A 1 372 ? 24.739 39.875 25.026 1.00 12.54 ? 372 VAL A CG2 1 ATOM 3052 N N . GLN A 1 373 ? 29.094 38.451 25.491 1.00 9.95 ? 373 GLN A N 1 ATOM 3053 C CA . GLN A 1 373 ? 30.421 38.831 25.948 1.00 9.89 ? 373 GLN A CA 1 ATOM 3054 C C . GLN A 1 373 ? 30.853 40.110 25.225 1.00 9.34 ? 373 GLN A C 1 ATOM 3055 O O . GLN A 1 373 ? 31.024 40.122 24.025 1.00 9.75 ? 373 GLN A O 1 ATOM 3056 C CB . GLN A 1 373 ? 31.414 37.685 25.708 1.00 10.72 ? 373 GLN A CB 1 ATOM 3057 C CG . GLN A 1 373 ? 32.897 37.976 26.015 1.00 13.14 ? 373 GLN A CG 1 ATOM 3058 C CD . GLN A 1 373 ? 33.188 38.320 27.470 1.00 16.15 ? 373 GLN A CD 1 ATOM 3059 O OE1 . GLN A 1 373 ? 34.129 39.043 27.766 1.00 17.36 ? 373 GLN A OE1 1 ATOM 3060 N NE2 . GLN A 1 373 ? 32.396 37.796 28.365 1.00 16.64 ? 373 GLN A NE2 1 ATOM 3061 N N . ALA A 1 374 ? 30.971 41.184 25.983 1.00 7.84 ? 374 ALA A N 1 ATOM 3062 C CA . ALA A 1 374 ? 31.218 42.496 25.404 1.00 8.34 ? 374 ALA A CA 1 ATOM 3063 C C . ALA A 1 374 ? 32.536 43.049 25.893 1.00 8.73 ? 374 ALA A C 1 ATOM 3064 O O . ALA A 1 374 ? 32.869 42.884 27.044 1.00 9.04 ? 374 ALA A O 1 ATOM 3065 C CB . ALA A 1 374 ? 30.107 43.429 25.772 1.00 8.18 ? 374 ALA A CB 1 ATOM 3066 N N . GLN A 1 375 ? 33.245 43.762 25.027 1.00 8.56 ? 375 GLN A N 1 ATOM 3067 C CA A GLN A 1 375 ? 34.568 44.296 25.377 0.50 8.61 ? 375 GLN A CA 1 ATOM 3068 C CA B GLN A 1 375 ? 34.556 44.306 25.376 0.50 8.94 ? 375 GLN A CA 1 ATOM 3069 C C . GLN A 1 375 ? 34.927 45.440 24.439 1.00 7.86 ? 375 GLN A C 1 ATOM 3070 O O . GLN A 1 375 ? 34.379 45.544 23.356 1.00 8.81 ? 375 GLN A O 1 ATOM 3071 C CB A GLN A 1 375 ? 35.659 43.220 25.300 0.50 9.56 ? 375 GLN A CB 1 ATOM 3072 C CB B GLN A 1 375 ? 35.638 43.230 25.293 0.50 10.15 ? 375 GLN A CB 1 ATOM 3073 C CG A GLN A 1 375 ? 35.639 42.382 24.022 0.50 11.43 ? 375 GLN A CG 1 ATOM 3074 C CG B GLN A 1 375 ? 35.628 42.497 23.988 0.50 13.51 ? 375 GLN A CG 1 ATOM 3075 C CD A GLN A 1 375 ? 34.767 41.152 24.156 0.50 12.32 ? 375 GLN A CD 1 ATOM 3076 C CD B GLN A 1 375 ? 35.930 41.061 24.166 0.50 17.81 ? 375 GLN A CD 1 ATOM 3077 O OE1 A GLN A 1 375 ? 34.941 40.358 25.089 0.50 14.49 ? 375 GLN A OE1 1 ATOM 3078 O OE1 B GLN A 1 375 ? 35.203 40.333 24.838 0.50 19.96 ? 375 GLN A OE1 1 ATOM 3079 N NE2 A GLN A 1 375 ? 33.815 40.988 23.239 0.50 10.73 ? 375 GLN A NE2 1 ATOM 3080 N NE2 B GLN A 1 375 ? 37.045 40.643 23.610 0.50 19.67 ? 375 GLN A NE2 1 ATOM 3081 N N . PHE A 1 376 ? 35.869 46.272 24.862 1.00 7.68 ? 376 PHE A N 1 ATOM 3082 C CA . PHE A 1 376 ? 36.478 47.192 23.897 1.00 7.12 ? 376 PHE A CA 1 ATOM 3083 C C . PHE A 1 376 ? 37.244 46.360 22.902 1.00 8.09 ? 376 PHE A C 1 ATOM 3084 O O . PHE A 1 376 ? 37.886 45.354 23.240 1.00 9.59 ? 376 PHE A O 1 ATOM 3085 C CB . PHE A 1 376 ? 37.432 48.142 24.601 1.00 7.29 ? 376 PHE A CB 1 ATOM 3086 C CG . PHE A 1 376 ? 36.742 49.090 25.534 1.00 8.79 ? 376 PHE A CG 1 ATOM 3087 C CD1 . PHE A 1 376 ? 35.713 49.913 25.087 1.00 9.57 ? 376 PHE A CD1 1 ATOM 3088 C CD2 . PHE A 1 376 ? 37.107 49.157 26.892 1.00 9.89 ? 376 PHE A CD2 1 ATOM 3089 C CE1 . PHE A 1 376 ? 35.055 50.789 25.985 1.00 11.86 ? 376 PHE A CE1 1 ATOM 3090 C CE2 . PHE A 1 376 ? 36.442 50.031 27.774 1.00 10.99 ? 376 PHE A CE2 1 ATOM 3091 C CZ . PHE A 1 376 ? 35.442 50.836 27.312 1.00 11.41 ? 376 PHE A CZ 1 ATOM 3092 N N . GLY A 1 377 ? 37.192 46.814 21.649 1.00 7.67 ? 377 GLY A N 1 ATOM 3093 C CA . GLY A 1 377 ? 37.892 46.094 20.598 1.00 8.48 ? 377 GLY A CA 1 ATOM 3094 C C . GLY A 1 377 ? 38.431 47.075 19.571 1.00 8.09 ? 377 GLY A C 1 ATOM 3095 O O . GLY A 1 377 ? 38.126 48.255 19.609 1.00 9.09 ? 377 GLY A O 1 ATOM 3096 N N . THR A 1 378 ? 39.187 46.519 18.622 1.00 9.14 ? 378 THR A N 1 ATOM 3097 C CA . THR A 1 378 ? 39.606 47.259 17.434 1.00 9.52 ? 378 THR A CA 1 ATOM 3098 C C . THR A 1 378 ? 38.836 46.722 16.245 1.00 8.35 ? 378 THR A C 1 ATOM 3099 O O . THR A 1 378 ? 38.158 45.687 16.285 1.00 8.75 ? 378 THR A O 1 ATOM 3100 C CB . THR A 1 378 ? 41.122 47.175 17.181 1.00 10.11 ? 378 THR A CB 1 ATOM 3101 O OG1 . THR A 1 378 ? 41.448 45.811 16.879 1.00 11.13 ? 378 THR A OG1 1 ATOM 3102 C CG2 . THR A 1 378 ? 41.933 47.563 18.423 1.00 13.43 ? 378 THR A CG2 1 ATOM 3103 N N . LEU A 1 379 ? 38.967 47.435 15.139 1.00 7.72 ? 379 LEU A N 1 ATOM 3104 C CA . LEU A 1 379 ? 38.323 47.034 13.917 1.00 7.61 ? 379 LEU A CA 1 ATOM 3105 C C . LEU A 1 379 ? 38.829 45.672 13.419 1.00 7.55 ? 379 LEU A C 1 ATOM 3106 O O . LEU A 1 379 ? 38.051 44.818 12.991 1.00 8.06 ? 379 LEU A O 1 ATOM 3107 C CB . LEU A 1 379 ? 38.501 48.143 12.850 1.00 8.06 ? 379 LEU A CB 1 ATOM 3108 C CG . LEU A 1 379 ? 37.745 47.914 11.523 1.00 7.14 ? 379 LEU A CG 1 ATOM 3109 C CD1 . LEU A 1 379 ? 36.243 47.860 11.726 1.00 8.23 ? 379 LEU A CD1 1 ATOM 3110 C CD2 . LEU A 1 379 ? 38.147 48.963 10.472 1.00 9.68 ? 379 LEU A CD2 1 ATOM 3111 N N . GLN A 1 380 ? 40.151 45.494 13.392 1.00 7.42 ? 380 GLN A N 1 ATOM 3112 C CA . GLN A 1 380 ? 40.728 44.201 12.994 1.00 8.84 ? 380 GLN A CA 1 ATOM 3113 C C . GLN A 1 380 ? 40.222 43.059 13.857 1.00 9.15 ? 380 GLN A C 1 ATOM 3114 O O . GLN A 1 380 ? 39.980 41.972 13.348 1.00 8.80 ? 380 GLN A O 1 ATOM 3115 C CB . GLN A 1 380 ? 42.262 44.241 13.005 1.00 9.49 ? 380 GLN A CB 1 ATOM 3116 C CG . GLN A 1 380 ? 42.922 42.981 12.451 1.00 12.33 ? 380 GLN A CG 1 ATOM 3117 C CD . GLN A 1 380 ? 42.607 42.790 10.994 1.00 15.55 ? 380 GLN A CD 1 ATOM 3118 O OE1 . GLN A 1 380 ? 42.670 43.747 10.211 1.00 16.58 ? 380 GLN A OE1 1 ATOM 3119 N NE2 . GLN A 1 380 ? 42.239 41.561 10.616 1.00 18.55 ? 380 GLN A NE2 1 ATOM 3120 N N . GLU A 1 381 ? 40.060 43.308 15.152 1.00 8.56 ? 381 GLU A N 1 ATOM 3121 C CA . GLU A 1 381 ? 39.575 42.262 16.033 1.00 9.01 ? 381 GLU A CA 1 ATOM 3122 C C . GLU A 1 381 ? 38.165 41.825 15.629 1.00 8.74 ? 381 GLU A C 1 ATOM 3123 O O . GLU A 1 381 ? 37.870 40.636 15.640 1.00 9.57 ? 381 GLU A O 1 ATOM 3124 C CB . GLU A 1 381 ? 39.525 42.761 17.470 1.00 10.27 ? 381 GLU A CB 1 ATOM 3125 C CG . GLU A 1 381 ? 40.788 42.663 18.286 1.00 15.83 ? 381 GLU A CG 1 ATOM 3126 C CD . GLU A 1 381 ? 40.415 42.983 19.715 1.00 21.58 ? 381 GLU A CD 1 ATOM 3127 O OE1 . GLU A 1 381 ? 40.361 44.165 20.005 1.00 19.44 ? 381 GLU A OE1 1 ATOM 3128 O OE2 . GLU A 1 381 ? 40.103 42.059 20.523 1.00 26.08 ? 381 GLU A OE2 1 ATOM 3129 N N . TYR A 1 382 ? 37.305 42.785 15.291 1.00 7.30 ? 382 TYR A N 1 ATOM 3130 C CA . TYR A 1 382 ? 35.968 42.480 14.811 1.00 6.82 ? 382 TYR A CA 1 ATOM 3131 C C . TYR A 1 382 ? 36.054 41.607 13.550 1.00 6.75 ? 382 TYR A C 1 ATOM 3132 O O . TYR A 1 382 ? 35.417 40.560 13.455 1.00 7.09 ? 382 TYR A O 1 ATOM 3133 C CB . TYR A 1 382 ? 35.187 43.781 14.496 1.00 7.01 ? 382 TYR A CB 1 ATOM 3134 C CG . TYR A 1 382 ? 33.912 43.495 13.764 1.00 7.21 ? 382 TYR A CG 1 ATOM 3135 C CD1 . TYR A 1 382 ? 32.826 42.905 14.426 1.00 8.25 ? 382 TYR A CD1 1 ATOM 3136 C CD2 . TYR A 1 382 ? 33.801 43.757 12.387 1.00 7.84 ? 382 TYR A CD2 1 ATOM 3137 C CE1 . TYR A 1 382 ? 31.685 42.572 13.753 1.00 8.56 ? 382 TYR A CE1 1 ATOM 3138 C CE2 . TYR A 1 382 ? 32.639 43.456 11.723 1.00 8.37 ? 382 TYR A CE2 1 ATOM 3139 C CZ . TYR A 1 382 ? 31.576 42.844 12.408 1.00 8.66 ? 382 TYR A CZ 1 ATOM 3140 O OH . TYR A 1 382 ? 30.369 42.517 11.804 1.00 9.55 ? 382 TYR A OH 1 ATOM 3141 N N . PHE A 1 383 ? 36.797 42.072 12.553 1.00 6.94 ? 383 PHE A N 1 ATOM 3142 C CA . PHE A 1 383 ? 36.834 41.328 11.315 1.00 6.74 ? 383 PHE A CA 1 ATOM 3143 C C . PHE A 1 383 ? 37.425 39.935 11.513 1.00 7.18 ? 383 PHE A C 1 ATOM 3144 O O . PHE A 1 383 ? 36.956 38.972 10.893 1.00 8.07 ? 383 PHE A O 1 ATOM 3145 C CB . PHE A 1 383 ? 37.604 42.092 10.236 1.00 6.82 ? 383 PHE A CB 1 ATOM 3146 C CG . PHE A 1 383 ? 36.817 43.240 9.628 1.00 7.03 ? 383 PHE A CG 1 ATOM 3147 C CD1 . PHE A 1 383 ? 35.611 43.011 8.985 1.00 7.11 ? 383 PHE A CD1 1 ATOM 3148 C CD2 . PHE A 1 383 ? 37.323 44.529 9.660 1.00 8.00 ? 383 PHE A CD2 1 ATOM 3149 C CE1 . PHE A 1 383 ? 34.907 44.051 8.386 1.00 7.50 ? 383 PHE A CE1 1 ATOM 3150 C CE2 . PHE A 1 383 ? 36.624 45.576 9.057 1.00 7.88 ? 383 PHE A CE2 1 ATOM 3151 C CZ . PHE A 1 383 ? 35.416 45.342 8.435 1.00 7.16 ? 383 PHE A CZ 1 ATOM 3152 N N . ASP A 1 384 ? 38.461 39.823 12.339 1.00 7.28 ? 384 ASP A N 1 ATOM 3153 C CA . ASP A 1 384 ? 39.048 38.494 12.596 1.00 8.87 ? 384 ASP A CA 1 ATOM 3154 C C . ASP A 1 384 ? 38.004 37.536 13.177 1.00 8.94 ? 384 ASP A C 1 ATOM 3155 O O . ASP A 1 384 ? 37.911 36.355 12.776 1.00 9.78 ? 384 ASP A O 1 ATOM 3156 C CB . ASP A 1 384 ? 40.214 38.593 13.580 1.00 9.98 ? 384 ASP A CB 1 ATOM 3157 C CG . ASP A 1 384 ? 41.438 39.193 12.998 1.00 14.25 ? 384 ASP A CG 1 ATOM 3158 O OD1 . ASP A 1 384 ? 41.561 39.337 11.758 1.00 17.41 ? 384 ASP A OD1 1 ATOM 3159 O OD2 . ASP A 1 384 ? 42.360 39.572 13.762 1.00 19.23 ? 384 ASP A OD2 1 ATOM 3160 N N . ALA A 1 385 ? 37.206 38.042 14.110 1.00 8.59 ? 385 ALA A N 1 ATOM 3161 C CA . ALA A 1 385 ? 36.175 37.230 14.733 1.00 8.32 ? 385 ALA A CA 1 ATOM 3162 C C . ALA A 1 385 ? 35.047 36.868 13.755 1.00 8.62 ? 385 ALA A C 1 ATOM 3163 O O . ALA A 1 385 ? 34.552 35.761 13.739 1.00 8.64 ? 385 ALA A O 1 ATOM 3164 C CB . ALA A 1 385 ? 35.625 37.928 15.996 1.00 8.77 ? 385 ALA A CB 1 ATOM 3165 N N . VAL A 1 386 ? 34.663 37.791 12.864 1.00 7.33 ? 386 VAL A N 1 ATOM 3166 C CA . VAL A 1 386 ? 33.672 37.479 11.855 1.00 9.13 ? 386 VAL A CA 1 ATOM 3167 C C . VAL A 1 386 ? 34.170 36.379 10.949 1.00 9.44 ? 386 VAL A C 1 ATOM 3168 O O . VAL A 1 386 ? 33.400 35.436 10.599 1.00 9.57 ? 386 VAL A O 1 ATOM 3169 C CB . VAL A 1 386 ? 33.379 38.740 10.999 1.00 7.70 ? 386 VAL A CB 1 ATOM 3170 C CG1 . VAL A 1 386 ? 32.569 38.417 9.758 1.00 11.32 ? 386 VAL A CG1 1 ATOM 3171 C CG2 . VAL A 1 386 ? 32.665 39.748 11.838 1.00 9.75 ? 386 VAL A CG2 1 ATOM 3172 N N . HIS A 1 387 ? 35.440 36.452 10.551 1.00 9.69 ? 387 HIS A N 1 ATOM 3173 C CA . HIS A 1 387 ? 35.915 35.423 9.619 1.00 10.33 ? 387 HIS A CA 1 ATOM 3174 C C . HIS A 1 387 ? 36.139 34.085 10.315 1.00 10.80 ? 387 HIS A C 1 ATOM 3175 O O . HIS A 1 387 ? 35.986 33.033 9.675 1.00 10.77 ? 387 HIS A O 1 ATOM 3176 C CB . HIS A 1 387 ? 37.135 35.859 8.819 1.00 10.20 ? 387 HIS A CB 1 ATOM 3177 C CG . HIS A 1 387 ? 36.834 37.006 7.907 1.00 10.27 ? 387 HIS A CG 1 ATOM 3178 N ND1 . HIS A 1 387 ? 35.911 36.901 6.892 1.00 13.82 ? 387 HIS A ND1 1 ATOM 3179 C CD2 . HIS A 1 387 ? 37.297 38.276 7.881 1.00 10.39 ? 387 HIS A CD2 1 ATOM 3180 C CE1 . HIS A 1 387 ? 35.840 38.058 6.253 1.00 12.86 ? 387 HIS A CE1 1 ATOM 3181 N NE2 . HIS A 1 387 ? 36.677 38.906 6.826 1.00 11.83 ? 387 HIS A NE2 1 ATOM 3182 N N . GLN A 1 388 ? 36.459 34.115 11.605 1.00 11.88 ? 388 GLN A N 1 ATOM 3183 C CA . GLN A 1 388 ? 36.467 32.874 12.404 1.00 13.04 ? 388 GLN A CA 1 ATOM 3184 C C . GLN A 1 388 ? 35.093 32.220 12.366 1.00 14.04 ? 388 GLN A C 1 ATOM 3185 O O . GLN A 1 388 ? 34.986 30.986 12.214 1.00 14.82 ? 388 GLN A O 1 ATOM 3186 C CB . GLN A 1 388 ? 36.919 33.172 13.820 1.00 14.16 ? 388 GLN A CB 1 ATOM 3187 C CG . GLN A 1 388 ? 38.433 33.363 13.944 1.00 18.62 ? 388 GLN A CG 1 ATOM 3188 C CD . GLN A 1 388 ? 38.874 34.149 15.184 1.00 23.00 ? 388 GLN A CD 1 ATOM 3189 O OE1 . GLN A 1 388 ? 38.089 34.354 16.118 1.00 26.88 ? 388 GLN A OE1 1 ATOM 3190 N NE2 . GLN A 1 388 ? 40.136 34.609 15.181 1.00 26.15 ? 388 GLN A NE2 1 ATOM 3191 N N . ALA A 1 389 ? 34.041 33.021 12.492 1.00 13.71 ? 389 ALA A N 1 ATOM 3192 C CA . ALA A 1 389 ? 32.659 32.533 12.464 1.00 15.36 ? 389 ALA A CA 1 ATOM 3193 C C . ALA A 1 389 ? 32.324 31.951 11.100 1.00 16.82 ? 389 ALA A C 1 ATOM 3194 O O . ALA A 1 389 ? 31.713 30.874 11.000 1.00 17.93 ? 389 ALA A O 1 ATOM 3195 C CB . ALA A 1 389 ? 31.696 33.653 12.847 1.00 14.97 ? 389 ALA A CB 1 ATOM 3196 N N . GLU A 1 390 ? 32.748 32.641 10.039 1.00 17.54 ? 390 GLU A N 1 ATOM 3197 C CA . GLU A 1 390 ? 32.594 32.165 8.663 1.00 18.79 ? 390 GLU A CA 1 ATOM 3198 C C . GLU A 1 390 ? 33.258 30.805 8.433 1.00 19.65 ? 390 GLU A C 1 ATOM 3199 O O . GLU A 1 390 ? 32.669 29.918 7.807 1.00 20.54 ? 390 GLU A O 1 ATOM 3200 C CB . GLU A 1 390 ? 33.186 33.207 7.709 1.00 18.56 ? 390 GLU A CB 1 ATOM 3201 C CG . GLU A 1 390 ? 32.993 32.931 6.220 1.00 19.67 ? 390 GLU A CG 1 ATOM 3202 C CD . GLU A 1 390 ? 33.728 33.938 5.356 1.00 21.19 ? 390 GLU A CD 1 ATOM 3203 O OE1 . GLU A 1 390 ? 34.615 34.656 5.897 1.00 23.12 ? 390 GLU A OE1 1 ATOM 3204 O OE2 . GLU A 1 390 ? 33.413 34.021 4.138 1.00 25.59 ? 390 GLU A OE2 1 ATOM 3205 N N . ARG A 1 391 ? 34.485 30.653 8.922 1.00 19.54 ? 391 ARG A N 1 ATOM 3206 C CA . ARG A 1 391 ? 35.224 29.400 8.754 1.00 21.66 ? 391 ARG A CA 1 ATOM 3207 C C . ARG A 1 391 ? 34.581 28.284 9.588 1.00 21.62 ? 391 ARG A C 1 ATOM 3208 O O . ARG A 1 391 ? 34.662 27.088 9.220 1.00 22.90 ? 391 ARG A O 1 ATOM 3209 C CB . ARG A 1 391 ? 36.684 29.577 9.154 1.00 21.49 ? 391 ARG A CB 1 ATOM 3210 C CG . ARG A 1 391 ? 37.508 30.485 8.248 1.00 23.60 ? 391 ARG A CG 1 ATOM 3211 C CD . ARG A 1 391 ? 39.019 30.376 8.484 1.00 23.94 ? 391 ARG A CD 1 ATOM 3212 N NE . ARG A 1 391 ? 39.428 30.833 9.815 1.00 27.74 ? 391 ARG A NE 1 ATOM 3213 C CZ . ARG A 1 391 ? 39.668 32.105 10.134 1.00 26.56 ? 391 ARG A CZ 1 ATOM 3214 N NH1 . ARG A 1 391 ? 39.523 33.062 9.232 1.00 28.55 ? 391 ARG A NH1 1 ATOM 3215 N NH2 . ARG A 1 391 ? 40.036 32.417 11.362 1.00 28.21 ? 391 ARG A NH2 1 ATOM 3216 N N . ALA A 1 392 ? 33.942 28.652 10.693 1.00 21.82 ? 392 ALA A N 1 ATOM 3217 C CA . ALA A 1 392 ? 33.221 27.671 11.525 1.00 22.52 ? 392 ALA A CA 1 ATOM 3218 C C . ALA A 1 392 ? 31.927 27.205 10.817 1.00 23.20 ? 392 ALA A C 1 ATOM 3219 O O . ALA A 1 392 ? 31.219 26.302 11.312 1.00 24.30 ? 392 ALA A O 1 ATOM 3220 C CB . ALA A 1 392 ? 32.916 28.241 12.903 1.00 23.12 ? 392 ALA A CB 1 ATOM 3221 N N . GLY A 1 393 ? 31.633 27.818 9.664 1.00 22.80 ? 393 GLY A N 1 ATOM 3222 C CA . GLY A 1 393 ? 30.450 27.497 8.881 1.00 22.67 ? 393 GLY A CA 1 ATOM 3223 C C . GLY A 1 393 ? 29.194 28.153 9.410 1.00 22.08 ? 393 GLY A C 1 ATOM 3224 O O . GLY A 1 393 ? 28.083 27.727 9.100 1.00 22.46 ? 393 GLY A O 1 ATOM 3225 N N . GLN A 1 394 ? 29.349 29.216 10.179 1.00 21.82 ? 394 GLN A N 1 ATOM 3226 C CA . GLN A 1 394 ? 28.240 29.855 10.838 1.00 22.22 ? 394 GLN A CA 1 ATOM 3227 C C . GLN A 1 394 ? 27.487 30.774 9.866 1.00 20.97 ? 394 GLN A C 1 ATOM 3228 O O . GLN A 1 394 ? 26.333 31.077 10.054 1.00 22.39 ? 394 GLN A O 1 ATOM 3229 C CB . GLN A 1 394 ? 28.805 30.669 11.997 1.00 23.34 ? 394 GLN A CB 1 ATOM 3230 C CG . GLN A 1 394 ? 27.873 30.963 13.090 1.00 25.68 ? 394 GLN A CG 1 ATOM 3231 C CD . GLN A 1 394 ? 28.402 32.056 13.971 1.00 25.22 ? 394 GLN A CD 1 ATOM 3232 O OE1 . GLN A 1 394 ? 28.076 33.216 13.796 1.00 20.06 ? 394 GLN A OE1 1 ATOM 3233 N NE2 . GLN A 1 394 ? 29.257 31.687 14.902 1.00 24.78 ? 394 GLN A NE2 1 ATOM 3234 N N . ALA A 1 395 ? 28.170 31.206 8.818 1.00 19.99 ? 395 ALA A N 1 ATOM 3235 C CA . ALA A 1 395 ? 27.667 32.206 7.889 1.00 19.56 ? 395 ALA A CA 1 ATOM 3236 C C . ALA A 1 395 ? 28.305 32.045 6.498 1.00 18.55 ? 395 ALA A C 1 ATOM 3237 O O . ALA A 1 395 ? 29.480 31.657 6.384 1.00 17.67 ? 395 ALA A O 1 ATOM 3238 C CB . ALA A 1 395 ? 27.949 33.600 8.453 1.00 19.88 ? 395 ALA A CB 1 ATOM 3239 N N . GLU A 1 396 ? 27.529 32.322 5.449 1.00 17.72 ? 396 GLU A N 1 ATOM 3240 C CA . GLU A 1 396 ? 28.071 32.558 4.105 1.00 18.60 ? 396 GLU A CA 1 ATOM 3241 C C . GLU A 1 396 ? 27.681 33.979 3.728 1.00 16.32 ? 396 GLU A C 1 ATOM 3242 O O . GLU A 1 396 ? 26.593 34.444 4.102 1.00 17.38 ? 396 GLU A O 1 ATOM 3243 C CB . GLU A 1 396 ? 27.536 31.551 3.066 1.00 18.86 ? 396 GLU A CB 1 ATOM 3244 C CG . GLU A 1 396 ? 26.013 31.429 3.014 1.00 23.43 ? 396 GLU A CG 1 ATOM 3245 C CD . GLU A 1 396 ? 25.513 30.339 2.065 1.00 24.50 ? 396 GLU A CD 1 ATOM 3246 O OE1 . GLU A 1 396 ? 26.200 30.029 1.062 1.00 31.53 ? 396 GLU A OE1 1 ATOM 3247 O OE2 . GLU A 1 396 ? 24.404 29.790 2.310 1.00 32.43 ? 396 GLU A OE2 1 ATOM 3248 N N . PHE A 1 397 ? 28.562 34.669 3.007 1.00 13.13 ? 397 PHE A N 1 ATOM 3249 C CA . PHE A 1 397 ? 28.287 36.051 2.672 1.00 10.88 ? 397 PHE A CA 1 ATOM 3250 C C . PHE A 1 397 ? 27.958 36.242 1.198 1.00 9.44 ? 397 PHE A C 1 ATOM 3251 O O . PHE A 1 397 ? 28.522 35.569 0.346 1.00 10.40 ? 397 PHE A O 1 ATOM 3252 C CB . PHE A 1 397 ? 29.518 36.892 3.031 1.00 10.95 ? 397 PHE A CB 1 ATOM 3253 C CG . PHE A 1 397 ? 29.802 36.913 4.501 1.00 9.33 ? 397 PHE A CG 1 ATOM 3254 C CD1 . PHE A 1 397 ? 28.951 37.580 5.368 1.00 8.61 ? 397 PHE A CD1 1 ATOM 3255 C CD2 . PHE A 1 397 ? 30.901 36.241 5.002 1.00 11.65 ? 397 PHE A CD2 1 ATOM 3256 C CE1 . PHE A 1 397 ? 29.200 37.599 6.734 1.00 9.52 ? 397 PHE A CE1 1 ATOM 3257 C CE2 . PHE A 1 397 ? 31.158 36.242 6.364 1.00 13.19 ? 397 PHE A CE2 1 ATOM 3258 C CZ . PHE A 1 397 ? 30.309 36.905 7.211 1.00 10.36 ? 397 PHE A CZ 1 ATOM 3259 N N . PRO A 1 398 ? 27.061 37.158 0.906 1.00 8.36 ? 398 PRO A N 1 ATOM 3260 C CA . PRO A 1 398 ? 26.696 37.442 -0.489 1.00 8.08 ? 398 PRO A CA 1 ATOM 3261 C C . PRO A 1 398 ? 27.783 38.202 -1.224 1.00 7.98 ? 398 PRO A C 1 ATOM 3262 O O . PRO A 1 398 ? 28.615 38.843 -0.609 1.00 8.25 ? 398 PRO A O 1 ATOM 3263 C CB . PRO A 1 398 ? 25.464 38.324 -0.339 1.00 9.73 ? 398 PRO A CB 1 ATOM 3264 C CG . PRO A 1 398 ? 25.678 39.048 0.973 1.00 8.77 ? 398 PRO A CG 1 ATOM 3265 C CD . PRO A 1 398 ? 26.302 37.996 1.843 1.00 9.25 ? 398 PRO A CD 1 ATOM 3266 N N . THR A 1 399 ? 27.757 38.083 -2.538 1.00 7.58 ? 399 THR A N 1 ATOM 3267 C CA . THR A 1 399 ? 28.653 38.840 -3.417 1.00 6.90 ? 399 THR A CA 1 ATOM 3268 C C . THR A 1 399 ? 27.906 40.053 -3.958 1.00 7.21 ? 399 THR A C 1 ATOM 3269 O O . THR A 1 399 ? 26.693 40.016 -4.129 1.00 7.05 ? 399 THR A O 1 ATOM 3270 C CB . THR A 1 399 ? 29.075 37.951 -4.554 1.00 7.72 ? 399 THR A CB 1 ATOM 3271 O OG1 . THR A 1 399 ? 27.894 37.477 -5.234 1.00 9.81 ? 399 THR A OG1 1 ATOM 3272 C CG2 . THR A 1 399 ? 29.845 36.725 -4.010 1.00 9.17 ? 399 THR A CG2 1 ATOM 3273 N N . LEU A 1 400 ? 28.660 41.132 -4.205 1.00 5.94 ? 400 LEU A N 1 ATOM 3274 C CA . LEU A 1 400 ? 28.028 42.370 -4.628 1.00 5.51 ? 400 LEU A CA 1 ATOM 3275 C C . LEU A 1 400 ? 28.943 43.039 -5.639 1.00 4.71 ? 400 LEU A C 1 ATOM 3276 O O . LEU A 1 400 ? 30.156 42.996 -5.502 1.00 5.61 ? 400 LEU A O 1 ATOM 3277 C CB . LEU A 1 400 ? 27.826 43.301 -3.417 1.00 5.65 ? 400 LEU A CB 1 ATOM 3278 C CG . LEU A 1 400 ? 27.123 44.641 -3.674 1.00 6.14 ? 400 LEU A CG 1 ATOM 3279 C CD1 . LEU A 1 400 ? 26.240 45.039 -2.477 1.00 8.00 ? 400 LEU A CD1 1 ATOM 3280 C CD2 . LEU A 1 400 ? 28.165 45.709 -3.942 1.00 7.51 ? 400 LEU A CD2 1 ATOM 3281 N N . SER A 1 401 ? 28.343 43.664 -6.657 1.00 5.34 ? 401 SER A N 1 ATOM 3282 C CA . SER A 1 401 ? 29.096 44.623 -7.449 1.00 5.31 ? 401 SER A CA 1 ATOM 3283 C C . SER A 1 401 ? 28.259 45.865 -7.645 1.00 4.74 ? 401 SER A C 1 ATOM 3284 O O . SER A 1 401 ? 27.044 45.850 -7.497 1.00 5.07 ? 401 SER A O 1 ATOM 3285 C CB . SER A 1 401 ? 29.511 44.045 -8.787 1.00 5.94 ? 401 SER A CB 1 ATOM 3286 O OG . SER A 1 401 ? 28.406 44.024 -9.697 1.00 6.34 ? 401 SER A OG 1 ATOM 3287 N N . GLY A 1 402 ? 28.934 46.966 -7.989 1.00 4.92 ? 402 GLY A N 1 ATOM 3288 C CA . GLY A 1 402 ? 28.263 48.236 -8.240 1.00 5.62 ? 402 GLY A CA 1 ATOM 3289 C C . GLY A 1 402 ? 28.889 49.320 -7.392 1.00 5.59 ? 402 GLY A C 1 ATOM 3290 O O . GLY A 1 402 ? 29.945 49.097 -6.769 1.00 7.23 ? 402 GLY A O 1 ATOM 3291 N N . ASP A 1 403 ? 28.255 50.476 -7.334 1.00 4.92 ? 403 ASP A N 1 ATOM 3292 C CA . ASP A 1 403 ? 28.740 51.595 -6.513 1.00 4.96 ? 403 ASP A CA 1 ATOM 3293 C C . ASP A 1 403 ? 27.586 52.088 -5.644 1.00 5.99 ? 403 ASP A C 1 ATOM 3294 O O . ASP A 1 403 ? 26.465 51.544 -5.677 1.00 7.00 ? 403 ASP A O 1 ATOM 3295 C CB . ASP A 1 403 ? 29.311 52.710 -7.397 1.00 5.59 ? 403 ASP A CB 1 ATOM 3296 C CG . ASP A 1 403 ? 28.274 53.500 -8.109 1.00 10.92 ? 403 ASP A CG 1 ATOM 3297 O OD1 . ASP A 1 403 ? 27.094 53.110 -8.154 1.00 13.75 ? 403 ASP A OD1 1 ATOM 3298 O OD2 . ASP A 1 403 ? 28.596 54.569 -8.643 1.00 13.36 ? 403 ASP A OD2 1 ATOM 3299 N N . PHE A 1 404 ? 27.880 53.077 -4.821 1.00 4.38 ? 404 PHE A N 1 ATOM 3300 C CA . PHE A 1 404 ? 26.950 53.627 -3.840 1.00 5.11 ? 404 PHE A CA 1 ATOM 3301 C C . PHE A 1 404 ? 26.829 55.138 -4.002 1.00 5.60 ? 404 PHE A C 1 ATOM 3302 O O . PHE A 1 404 ? 26.912 55.885 -3.049 1.00 6.75 ? 404 PHE A O 1 ATOM 3303 C CB . PHE A 1 404 ? 27.316 53.175 -2.398 1.00 4.68 ? 404 PHE A CB 1 ATOM 3304 C CG . PHE A 1 404 ? 27.274 51.681 -2.219 1.00 4.78 ? 404 PHE A CG 1 ATOM 3305 C CD1 . PHE A 1 404 ? 26.048 51.040 -2.070 1.00 5.60 ? 404 PHE A CD1 1 ATOM 3306 C CD2 . PHE A 1 404 ? 28.442 50.948 -2.209 1.00 5.24 ? 404 PHE A CD2 1 ATOM 3307 C CE1 . PHE A 1 404 ? 26.019 49.650 -1.925 1.00 5.56 ? 404 PHE A CE1 1 ATOM 3308 C CE2 . PHE A 1 404 ? 28.401 49.571 -2.058 1.00 6.62 ? 404 PHE A CE2 1 ATOM 3309 C CZ . PHE A 1 404 ? 27.183 48.946 -1.897 1.00 6.20 ? 404 PHE A CZ 1 ATOM 3310 N N . PHE A 1 405 ? 26.612 55.545 -5.248 1.00 6.00 ? 405 PHE A N 1 ATOM 3311 C CA . PHE A 1 405 ? 26.230 56.920 -5.583 1.00 5.26 ? 405 PHE A CA 1 ATOM 3312 C C . PHE A 1 405 ? 24.863 56.868 -6.243 1.00 5.54 ? 405 PHE A C 1 ATOM 3313 O O . PHE A 1 405 ? 24.567 55.881 -6.915 1.00 6.62 ? 405 PHE A O 1 ATOM 3314 C CB . PHE A 1 405 ? 27.224 57.519 -6.585 1.00 6.05 ? 405 PHE A CB 1 ATOM 3315 C CG . PHE A 1 405 ? 28.622 57.621 -6.047 1.00 5.63 ? 405 PHE A CG 1 ATOM 3316 C CD1 . PHE A 1 405 ? 28.880 58.448 -4.971 1.00 7.08 ? 405 PHE A CD1 1 ATOM 3317 C CD2 . PHE A 1 405 ? 29.641 56.910 -6.621 1.00 5.60 ? 405 PHE A CD2 1 ATOM 3318 C CE1 . PHE A 1 405 ? 30.189 58.535 -4.425 1.00 7.33 ? 405 PHE A CE1 1 ATOM 3319 C CE2 . PHE A 1 405 ? 30.935 56.988 -6.095 1.00 6.73 ? 405 PHE A CE2 1 ATOM 3320 C CZ . PHE A 1 405 ? 31.186 57.814 -4.979 1.00 6.11 ? 405 PHE A CZ 1 ATOM 3321 N N . THR A 1 406 ? 24.065 57.939 -6.159 1.00 5.48 ? 406 THR A N 1 ATOM 3322 C CA . THR A 1 406 ? 24.298 59.127 -5.349 1.00 5.04 ? 406 THR A CA 1 ATOM 3323 C C . THR A 1 406 ? 23.647 58.991 -3.989 1.00 5.61 ? 406 THR A C 1 ATOM 3324 O O . THR A 1 406 ? 22.487 58.578 -3.848 1.00 6.08 ? 406 THR A O 1 ATOM 3325 C CB . THR A 1 406 ? 23.760 60.332 -6.142 1.00 5.63 ? 406 THR A CB 1 ATOM 3326 O OG1 . THR A 1 406 ? 24.700 60.552 -7.197 1.00 6.88 ? 406 THR A OG1 1 ATOM 3327 C CG2 . THR A 1 406 ? 23.677 61.619 -5.325 1.00 6.40 ? 406 THR A CG2 1 ATOM 3328 N N . TYR A 1 407 ? 24.409 59.365 -2.980 1.00 6.44 ? 407 TYR A N 1 ATOM 3329 C CA . TYR A 1 407 ? 23.985 59.267 -1.600 1.00 5.73 ? 407 TYR A CA 1 ATOM 3330 C C . TYR A 1 407 ? 22.850 60.231 -1.273 1.00 6.45 ? 407 TYR A C 1 ATOM 3331 O O . TYR A 1 407 ? 22.866 61.352 -1.701 1.00 6.87 ? 407 TYR A O 1 ATOM 3332 C CB . TYR A 1 407 ? 25.193 59.557 -0.733 1.00 5.83 ? 407 TYR A CB 1 ATOM 3333 C CG . TYR A 1 407 ? 24.968 59.669 0.754 1.00 4.86 ? 407 TYR A CG 1 ATOM 3334 C CD1 . TYR A 1 407 ? 24.520 58.594 1.506 1.00 6.77 ? 407 TYR A CD1 1 ATOM 3335 C CD2 . TYR A 1 407 ? 25.300 60.824 1.409 1.00 5.92 ? 407 TYR A CD2 1 ATOM 3336 C CE1 . TYR A 1 407 ? 24.390 58.697 2.859 1.00 6.44 ? 407 TYR A CE1 1 ATOM 3337 C CE2 . TYR A 1 407 ? 25.168 60.938 2.756 1.00 5.99 ? 407 TYR A CE2 1 ATOM 3338 C CZ . TYR A 1 407 ? 24.713 59.867 3.480 1.00 5.39 ? 407 TYR A CZ 1 ATOM 3339 O OH . TYR A 1 407 ? 24.601 59.948 4.831 1.00 7.19 ? 407 TYR A OH 1 ATOM 3340 N N . ALA A 1 408 ? 21.880 59.751 -0.516 1.00 7.04 ? 408 ALA A N 1 ATOM 3341 C CA . ALA A 1 408 ? 20.946 60.639 0.214 1.00 6.72 ? 408 ALA A CA 1 ATOM 3342 C C . ALA A 1 408 ? 20.892 60.166 1.641 1.00 6.65 ? 408 ALA A C 1 ATOM 3343 O O . ALA A 1 408 ? 20.781 58.948 1.897 1.00 6.65 ? 408 ALA A O 1 ATOM 3344 C CB . ALA A 1 408 ? 19.530 60.579 -0.395 1.00 7.87 ? 408 ALA A CB 1 ATOM 3345 N N . ASP A 1 409 ? 20.996 61.118 2.588 1.00 6.05 ? 409 ASP A N 1 ATOM 3346 C CA . ASP A 1 409 ? 20.909 60.744 4.004 1.00 7.16 ? 409 ASP A CA 1 ATOM 3347 C C . ASP A 1 409 ? 19.476 60.766 4.506 1.00 7.73 ? 409 ASP A C 1 ATOM 3348 O O . ASP A 1 409 ? 19.191 60.123 5.521 1.00 8.51 ? 409 ASP A O 1 ATOM 3349 C CB . ASP A 1 409 ? 21.798 61.595 4.928 1.00 8.34 ? 409 ASP A CB 1 ATOM 3350 C CG . ASP A 1 409 ? 21.575 63.109 4.806 1.00 7.10 ? 409 ASP A CG 1 ATOM 3351 O OD1 . ASP A 1 409 ? 20.957 63.630 3.832 1.00 7.11 ? 409 ASP A OD1 1 ATOM 3352 O OD2 . ASP A 1 409 ? 22.103 63.867 5.680 1.00 8.40 ? 409 ASP A OD2 1 ATOM 3353 N N . ARG A 1 410 ? 18.606 61.516 3.826 1.00 7.04 ? 410 ARG A N 1 ATOM 3354 C CA . ARG A 1 410 ? 17.194 61.595 4.247 1.00 8.81 ? 410 ARG A CA 1 ATOM 3355 C C . ARG A 1 410 ? 16.370 62.212 3.146 1.00 9.01 ? 410 ARG A C 1 ATOM 3356 O O . ARG A 1 410 ? 16.877 62.984 2.316 1.00 9.32 ? 410 ARG A O 1 ATOM 3357 C CB . ARG A 1 410 ? 17.032 62.360 5.569 1.00 8.90 ? 410 ARG A CB 1 ATOM 3358 C CG . ARG A 1 410 ? 17.535 63.781 5.592 1.00 11.42 ? 410 ARG A CG 1 ATOM 3359 C CD . ARG A 1 410 ? 17.493 64.383 6.998 1.00 11.82 ? 410 ARG A CD 1 ATOM 3360 N NE . ARG A 1 410 ? 18.119 65.715 7.066 1.00 12.88 ? 410 ARG A NE 1 ATOM 3361 C CZ . ARG A 1 410 ? 17.507 66.872 6.816 1.00 15.47 ? 410 ARG A CZ 1 ATOM 3362 N NH1 . ARG A 1 410 ? 16.230 66.898 6.412 1.00 16.89 ? 410 ARG A NH1 1 ATOM 3363 N NH2 . ARG A 1 410 ? 18.197 68.003 6.914 1.00 14.78 ? 410 ARG A NH2 1 ATOM 3364 N N . SER A 1 411 ? 15.082 61.849 3.116 1.00 9.55 ? 411 SER A N 1 ATOM 3365 C CA A SER A 1 411 ? 14.101 62.414 2.184 0.50 10.61 ? 411 SER A CA 1 ATOM 3366 C CA B SER A 1 411 ? 14.138 62.491 2.213 0.50 10.10 ? 411 SER A CA 1 ATOM 3367 C C . SER A 1 411 ? 14.659 62.528 0.761 1.00 9.63 ? 411 SER A C 1 ATOM 3368 O O . SER A 1 411 ? 15.154 61.517 0.221 1.00 10.21 ? 411 SER A O 1 ATOM 3369 C CB A SER A 1 411 ? 13.505 63.710 2.734 0.50 11.89 ? 411 SER A CB 1 ATOM 3370 C CB B SER A 1 411 ? 13.848 63.889 2.748 0.50 11.18 ? 411 SER A CB 1 ATOM 3371 O OG A SER A 1 411 ? 14.495 64.673 3.021 0.50 14.36 ? 411 SER A OG 1 ATOM 3372 O OG B SER A 1 411 ? 12.807 64.497 2.020 0.50 11.24 ? 411 SER A OG 1 ATOM 3373 N N . ASP A 1 412 ? 14.571 63.712 0.121 1.00 9.29 ? 412 ASP A N 1 ATOM 3374 C CA . ASP A 1 412 ? 15.095 63.902 -1.240 1.00 7.83 ? 412 ASP A CA 1 ATOM 3375 C C . ASP A 1 412 ? 16.439 64.641 -1.243 1.00 7.67 ? 412 ASP A C 1 ATOM 3376 O O . ASP A 1 412 ? 16.810 65.261 -2.227 1.00 8.38 ? 412 ASP A O 1 ATOM 3377 C CB . ASP A 1 412 ? 14.115 64.705 -2.103 1.00 9.87 ? 412 ASP A CB 1 ATOM 3378 C CG . ASP A 1 412 ? 13.887 66.094 -1.561 1.00 9.98 ? 412 ASP A CG 1 ATOM 3379 O OD1 . ASP A 1 412 ? 14.347 66.432 -0.446 1.00 10.48 ? 412 ASP A OD1 1 ATOM 3380 O OD2 . ASP A 1 412 ? 13.240 66.930 -2.237 1.00 12.14 ? 412 ASP A OD2 1 ATOM 3381 N N . ASN A 1 413 ? 17.124 64.622 -0.099 1.00 7.24 ? 413 ASN A N 1 ATOM 3382 C CA . ASN A 1 413 ? 18.368 65.378 0.074 1.00 6.91 ? 413 ASN A CA 1 ATOM 3383 C C . ASN A 1 413 ? 19.543 64.550 -0.469 1.00 6.99 ? 413 ASN A C 1 ATOM 3384 O O . ASN A 1 413 ? 20.220 63.862 0.285 1.00 7.54 ? 413 ASN A O 1 ATOM 3385 C CB . ASN A 1 413 ? 18.581 65.690 1.547 1.00 6.90 ? 413 ASN A CB 1 ATOM 3386 C CG . ASN A 1 413 ? 17.641 66.760 2.133 1.00 7.76 ? 413 ASN A CG 1 ATOM 3387 O OD1 . ASN A 1 413 ? 17.940 67.274 3.207 1.00 9.76 ? 413 ASN A OD1 1 ATOM 3388 N ND2 . ASN A 1 413 ? 16.556 67.121 1.440 1.00 9.09 ? 413 ASN A ND2 1 ATOM 3389 N N . TYR A 1 414 ? 19.724 64.601 -1.789 1.00 6.00 ? 414 TYR A N 1 ATOM 3390 C CA . TYR A 1 414 ? 20.793 63.892 -2.485 1.00 6.51 ? 414 TYR A CA 1 ATOM 3391 C C . TYR A 1 414 ? 22.036 64.763 -2.551 1.00 6.62 ? 414 TYR A C 1 ATOM 3392 O O . TYR A 1 414 ? 21.952 65.943 -2.853 1.00 6.45 ? 414 TYR A O 1 ATOM 3393 C CB . TYR A 1 414 ? 20.351 63.520 -3.905 1.00 6.61 ? 414 TYR A CB 1 ATOM 3394 C CG . TYR A 1 414 ? 19.368 62.363 -3.911 1.00 6.28 ? 414 TYR A CG 1 ATOM 3395 C CD1 . TYR A 1 414 ? 18.012 62.580 -3.748 1.00 7.13 ? 414 TYR A CD1 1 ATOM 3396 C CD2 . TYR A 1 414 ? 19.814 61.072 -4.081 1.00 8.26 ? 414 TYR A CD2 1 ATOM 3397 C CE1 . TYR A 1 414 ? 17.127 61.502 -3.684 1.00 7.49 ? 414 TYR A CE1 1 ATOM 3398 C CE2 . TYR A 1 414 ? 18.937 59.997 -4.052 1.00 7.46 ? 414 TYR A CE2 1 ATOM 3399 C CZ . TYR A 1 414 ? 17.600 60.222 -3.875 1.00 7.49 ? 414 TYR A CZ 1 ATOM 3400 O OH . TYR A 1 414 ? 16.721 59.139 -3.847 1.00 8.04 ? 414 TYR A OH 1 ATOM 3401 N N . TRP A 1 415 ? 23.168 64.132 -2.248 1.00 5.93 ? 415 TRP A N 1 ATOM 3402 C CA . TRP A 1 415 ? 24.418 64.871 -2.120 1.00 5.82 ? 415 TRP A CA 1 ATOM 3403 C C . TRP A 1 415 ? 25.135 64.916 -3.457 1.00 7.56 ? 415 TRP A C 1 ATOM 3404 O O . TRP A 1 415 ? 26.256 64.410 -3.578 1.00 8.99 ? 415 TRP A O 1 ATOM 3405 C CB . TRP A 1 415 ? 25.273 64.187 -1.066 1.00 6.27 ? 415 TRP A CB 1 ATOM 3406 C CG . TRP A 1 415 ? 24.711 64.264 0.336 1.00 5.84 ? 415 TRP A CG 1 ATOM 3407 C CD1 . TRP A 1 415 ? 23.407 64.038 0.744 1.00 6.50 ? 415 TRP A CD1 1 ATOM 3408 C CD2 . TRP A 1 415 ? 25.451 64.533 1.525 1.00 6.12 ? 415 TRP A CD2 1 ATOM 3409 N NE1 . TRP A 1 415 ? 23.322 64.152 2.115 1.00 6.20 ? 415 TRP A NE1 1 ATOM 3410 C CE2 . TRP A 1 415 ? 24.569 64.434 2.624 1.00 6.99 ? 415 TRP A CE2 1 ATOM 3411 C CE3 . TRP A 1 415 ? 26.803 64.801 1.779 1.00 7.76 ? 415 TRP A CE3 1 ATOM 3412 C CZ2 . TRP A 1 415 ? 24.975 64.656 3.943 1.00 7.62 ? 415 TRP A CZ2 1 ATOM 3413 C CZ3 . TRP A 1 415 ? 27.212 65.009 3.091 1.00 6.96 ? 415 TRP A CZ3 1 ATOM 3414 C CH2 . TRP A 1 415 ? 26.307 64.931 4.166 1.00 8.21 ? 415 TRP A CH2 1 ATOM 3415 N N . SER A 1 416 ? 24.510 65.518 -4.464 1.00 5.52 ? 416 SER A N 1 ATOM 3416 C CA . SER A 1 416 ? 25.157 65.634 -5.750 1.00 5.83 ? 416 SER A CA 1 ATOM 3417 C C . SER A 1 416 ? 25.695 67.026 -5.972 1.00 6.36 ? 416 SER A C 1 ATOM 3418 O O . SER A 1 416 ? 26.383 67.248 -6.954 1.00 6.70 ? 416 SER A O 1 ATOM 3419 C CB . SER A 1 416 ? 24.207 65.223 -6.879 1.00 6.00 ? 416 SER A CB 1 ATOM 3420 O OG . SER A 1 416 ? 22.915 65.778 -6.689 1.00 7.00 ? 416 SER A OG 1 ATOM 3421 N N . GLY A 1 417 ? 25.482 67.940 -5.035 1.00 4.81 ? 417 GLY A N 1 ATOM 3422 C CA . GLY A 1 417 ? 26.066 69.262 -5.227 1.00 5.40 ? 417 GLY A CA 1 ATOM 3423 C C . GLY A 1 417 ? 27.563 69.270 -5.140 1.00 4.16 ? 417 GLY A C 1 ATOM 3424 O O . GLY A 1 417 ? 28.222 70.004 -5.881 1.00 5.14 ? 417 GLY A O 1 ATOM 3425 N N . TYR A 1 418 ? 28.107 68.459 -4.231 1.00 4.05 ? 418 TYR A N 1 ATOM 3426 C CA . TYR A 1 418 ? 29.559 68.504 -4.045 1.00 4.44 ? 418 TYR A CA 1 ATOM 3427 C C . TYR A 1 418 ? 30.311 67.894 -5.235 1.00 4.87 ? 418 TYR A C 1 ATOM 3428 O O . TYR A 1 418 ? 31.555 67.928 -5.277 1.00 6.03 ? 418 TYR A O 1 ATOM 3429 C CB . TYR A 1 418 ? 29.952 67.806 -2.732 1.00 5.04 ? 418 TYR A CB 1 ATOM 3430 C CG . TYR A 1 418 ? 30.074 66.302 -2.806 1.00 5.61 ? 418 TYR A CG 1 ATOM 3431 C CD1 . TYR A 1 418 ? 28.980 65.473 -2.628 1.00 5.92 ? 418 TYR A CD1 1 ATOM 3432 C CD2 . TYR A 1 418 ? 31.316 65.711 -3.000 1.00 5.64 ? 418 TYR A CD2 1 ATOM 3433 C CE1 . TYR A 1 418 ? 29.113 64.088 -2.679 1.00 4.50 ? 418 TYR A CE1 1 ATOM 3434 C CE2 . TYR A 1 418 ? 31.462 64.357 -3.031 1.00 4.35 ? 418 TYR A CE2 1 ATOM 3435 C CZ . TYR A 1 418 ? 30.363 63.547 -2.869 1.00 4.40 ? 418 TYR A CZ 1 ATOM 3436 O OH . TYR A 1 418 ? 30.539 62.176 -2.899 1.00 6.57 ? 418 TYR A OH 1 ATOM 3437 N N . TYR A 1 419 ? 29.603 67.277 -6.192 1.00 4.65 ? 419 TYR A N 1 ATOM 3438 C CA . TYR A 1 419 ? 30.273 66.865 -7.410 1.00 4.15 ? 419 TYR A CA 1 ATOM 3439 C C . TYR A 1 419 ? 30.794 68.073 -8.205 1.00 4.89 ? 419 TYR A C 1 ATOM 3440 O O . TYR A 1 419 ? 31.674 67.899 -9.063 1.00 5.41 ? 419 TYR A O 1 ATOM 3441 C CB . TYR A 1 419 ? 29.373 66.041 -8.333 1.00 4.58 ? 419 TYR A CB 1 ATOM 3442 C CG . TYR A 1 419 ? 28.723 64.854 -7.700 1.00 4.44 ? 419 TYR A CG 1 ATOM 3443 C CD1 . TYR A 1 419 ? 29.325 64.168 -6.644 1.00 4.71 ? 419 TYR A CD1 1 ATOM 3444 C CD2 . TYR A 1 419 ? 27.553 64.323 -8.245 1.00 3.78 ? 419 TYR A CD2 1 ATOM 3445 C CE1 . TYR A 1 419 ? 28.737 63.021 -6.087 1.00 4.93 ? 419 TYR A CE1 1 ATOM 3446 C CE2 . TYR A 1 419 ? 26.959 63.210 -7.696 1.00 4.20 ? 419 TYR A CE2 1 ATOM 3447 C CZ . TYR A 1 419 ? 27.568 62.536 -6.658 1.00 4.33 ? 419 TYR A CZ 1 ATOM 3448 O OH . TYR A 1 419 ? 26.986 61.415 -6.120 1.00 5.35 ? 419 TYR A OH 1 ATOM 3449 N N . THR A 1 420 ? 30.297 69.279 -7.889 1.00 5.02 ? 420 THR A N 1 ATOM 3450 C CA . THR A 1 420 ? 30.712 70.498 -8.599 1.00 4.77 ? 420 THR A CA 1 ATOM 3451 C C . THR A 1 420 ? 31.250 71.571 -7.678 1.00 5.63 ? 420 THR A C 1 ATOM 3452 O O . THR A 1 420 ? 32.030 72.401 -8.144 1.00 6.96 ? 420 THR A O 1 ATOM 3453 C CB . THR A 1 420 ? 29.493 71.022 -9.375 1.00 5.63 ? 420 THR A CB 1 ATOM 3454 O OG1 . THR A 1 420 ? 29.057 69.981 -10.266 1.00 6.83 ? 420 THR A OG1 1 ATOM 3455 C CG2 . THR A 1 420 ? 29.837 72.205 -10.274 1.00 7.52 ? 420 THR A CG2 1 ATOM 3456 N N . SER A 1 421 ? 30.882 71.586 -6.401 1.00 4.83 ? 421 SER A N 1 ATOM 3457 C CA . SER A 1 421 ? 31.255 72.719 -5.565 1.00 4.89 ? 421 SER A CA 1 ATOM 3458 C C . SER A 1 421 ? 32.738 73.069 -5.602 1.00 6.01 ? 421 SER A C 1 ATOM 3459 O O . SER A 1 421 ? 33.588 72.180 -5.534 1.00 6.20 ? 421 SER A O 1 ATOM 3460 C CB . SER A 1 421 ? 30.861 72.436 -4.125 1.00 5.46 ? 421 SER A CB 1 ATOM 3461 O OG . SER A 1 421 ? 29.469 72.249 -4.011 1.00 5.95 ? 421 SER A OG 1 ATOM 3462 N N . ARG A 1 422 ? 33.032 74.370 -5.657 1.00 5.55 ? 422 ARG A N 1 ATOM 3463 C CA . ARG A 1 422 ? 34.423 74.862 -5.712 1.00 6.19 ? 422 ARG A CA 1 ATOM 3464 C C . ARG A 1 422 ? 35.174 74.224 -6.888 1.00 6.19 ? 422 ARG A C 1 ATOM 3465 O O . ARG A 1 422 ? 36.202 73.558 -6.731 1.00 6.11 ? 422 ARG A O 1 ATOM 3466 C CB . ARG A 1 422 ? 35.160 74.628 -4.384 1.00 6.44 ? 422 ARG A CB 1 ATOM 3467 C CG . ARG A 1 422 ? 34.886 75.678 -3.272 1.00 7.08 ? 422 ARG A CG 1 ATOM 3468 C CD . ARG A 1 422 ? 33.420 75.816 -2.827 1.00 6.23 ? 422 ARG A CD 1 ATOM 3469 N NE . ARG A 1 422 ? 33.417 76.809 -1.748 1.00 7.68 ? 422 ARG A NE 1 ATOM 3470 C CZ . ARG A 1 422 ? 33.524 76.515 -0.463 1.00 7.09 ? 422 ARG A CZ 1 ATOM 3471 N NH1 . ARG A 1 422 ? 33.443 75.274 -0.049 1.00 7.40 ? 422 ARG A NH1 1 ATOM 3472 N NH2 . ARG A 1 422 ? 33.670 77.506 0.428 1.00 6.94 ? 422 ARG A NH2 1 ATOM 3473 N N . PRO A 1 423 ? 34.677 74.438 -8.087 1.00 5.10 ? 423 PRO A N 1 ATOM 3474 C CA . PRO A 1 423 ? 35.270 73.790 -9.258 1.00 5.51 ? 423 PRO A CA 1 ATOM 3475 C C . PRO A 1 423 ? 36.679 74.296 -9.605 1.00 5.72 ? 423 PRO A C 1 ATOM 3476 O O . PRO A 1 423 ? 37.407 73.596 -10.259 1.00 5.25 ? 423 PRO A O 1 ATOM 3477 C CB . PRO A 1 423 ? 34.242 74.095 -10.381 1.00 6.45 ? 423 PRO A CB 1 ATOM 3478 C CG . PRO A 1 423 ? 33.710 75.426 -9.968 1.00 6.34 ? 423 PRO A CG 1 ATOM 3479 C CD . PRO A 1 423 ? 33.535 75.310 -8.447 1.00 5.71 ? 423 PRO A CD 1 ATOM 3480 N N . TYR A 1 424 ? 37.064 75.506 -9.200 1.00 5.67 ? 424 TYR A N 1 ATOM 3481 C CA . TYR A 1 424 ? 38.437 75.956 -9.445 1.00 4.84 ? 424 TYR A CA 1 ATOM 3482 C C . TYR A 1 424 ? 39.405 74.957 -8.799 1.00 4.87 ? 424 TYR A C 1 ATOM 3483 O O . TYR A 1 424 ? 40.406 74.580 -9.420 1.00 5.74 ? 424 TYR A O 1 ATOM 3484 C CB . TYR A 1 424 ? 38.631 77.337 -8.832 1.00 6.44 ? 424 TYR A CB 1 ATOM 3485 C CG . TYR A 1 424 ? 40.011 77.897 -9.038 1.00 5.97 ? 424 TYR A CG 1 ATOM 3486 C CD1 . TYR A 1 424 ? 41.043 77.650 -8.139 1.00 7.29 ? 424 TYR A CD1 1 ATOM 3487 C CD2 . TYR A 1 424 ? 40.279 78.657 -10.165 1.00 7.83 ? 424 TYR A CD2 1 ATOM 3488 C CE1 . TYR A 1 424 ? 42.322 78.208 -8.338 1.00 10.04 ? 424 TYR A CE1 1 ATOM 3489 C CE2 . TYR A 1 424 ? 41.528 79.185 -10.383 1.00 10.45 ? 424 TYR A CE2 1 ATOM 3490 C CZ . TYR A 1 424 ? 42.546 78.968 -9.469 1.00 8.92 ? 424 TYR A CZ 1 ATOM 3491 O OH . TYR A 1 424 ? 43.812 79.519 -9.726 1.00 12.86 ? 424 TYR A OH 1 ATOM 3492 N N . HIS A 1 425 ? 39.075 74.522 -7.567 1.00 4.90 ? 425 HIS A N 1 ATOM 3493 C CA . HIS A 1 425 ? 40.013 73.658 -6.842 1.00 4.78 ? 425 HIS A CA 1 ATOM 3494 C C . HIS A 1 425 ? 39.953 72.231 -7.353 1.00 5.26 ? 425 HIS A C 1 ATOM 3495 O O . HIS A 1 425 ? 40.950 71.481 -7.281 1.00 5.16 ? 425 HIS A O 1 ATOM 3496 C CB . HIS A 1 425 ? 39.812 73.808 -5.332 1.00 6.65 ? 425 HIS A CB 1 ATOM 3497 C CG . HIS A 1 425 ? 39.877 75.231 -4.910 1.00 8.18 ? 425 HIS A CG 1 ATOM 3498 N ND1 . HIS A 1 425 ? 38.778 76.059 -4.957 1.00 8.23 ? 425 HIS A ND1 1 ATOM 3499 C CD2 . HIS A 1 425 ? 40.943 76.022 -4.642 1.00 9.31 ? 425 HIS A CD2 1 ATOM 3500 C CE1 . HIS A 1 425 ? 39.152 77.289 -4.635 1.00 7.91 ? 425 HIS A CE1 1 ATOM 3501 N NE2 . HIS A 1 425 ? 40.459 77.289 -4.430 1.00 9.33 ? 425 HIS A NE2 1 ATOM 3502 N N . LYS A 1 426 ? 38.766 71.830 -7.830 1.00 4.58 ? 426 LYS A N 1 ATOM 3503 C CA . LYS A 1 426 ? 38.645 70.535 -8.502 1.00 4.89 ? 426 LYS A CA 1 ATOM 3504 C C . LYS A 1 426 ? 39.530 70.447 -9.738 1.00 4.60 ? 426 LYS A C 1 ATOM 3505 O O . LYS A 1 426 ? 40.190 69.440 -9.987 1.00 5.42 ? 426 LYS A O 1 ATOM 3506 C CB . LYS A 1 426 ? 37.193 70.281 -8.867 1.00 5.13 ? 426 LYS A CB 1 ATOM 3507 C CG . LYS A 1 426 ? 36.288 69.938 -7.679 1.00 4.92 ? 426 LYS A CG 1 ATOM 3508 C CD . LYS A 1 426 ? 34.805 69.922 -8.053 1.00 6.09 ? 426 LYS A CD 1 ATOM 3509 C CE . LYS A 1 426 ? 33.948 69.009 -7.177 1.00 7.02 ? 426 LYS A CE 1 ATOM 3510 N NZ . LYS A 1 426 ? 33.886 69.477 -5.738 1.00 6.12 ? 426 LYS A NZ 1 ATOM 3511 N N . ARG A 1 427 ? 39.566 71.526 -10.520 1.00 5.15 ? 427 ARG A N 1 ATOM 3512 C CA . ARG A 1 427 ? 40.456 71.550 -11.646 1.00 5.74 ? 427 ARG A CA 1 ATOM 3513 C C . ARG A 1 427 ? 41.925 71.584 -11.221 1.00 5.60 ? 427 ARG A C 1 ATOM 3514 O O . ARG A 1 427 ? 42.756 70.881 -11.762 1.00 5.60 ? 427 ARG A O 1 ATOM 3515 C CB . ARG A 1 427 ? 40.088 72.768 -12.521 1.00 5.81 ? 427 ARG A CB 1 ATOM 3516 C CG . ARG A 1 427 ? 41.013 73.014 -13.699 1.00 6.55 ? 427 ARG A CG 1 ATOM 3517 C CD . ARG A 1 427 ? 41.094 71.902 -14.741 1.00 8.02 ? 427 ARG A CD 1 ATOM 3518 N NE . ARG A 1 427 ? 42.163 72.275 -15.675 1.00 8.75 ? 427 ARG A NE 1 ATOM 3519 C CZ . ARG A 1 427 ? 42.986 71.433 -16.238 1.00 8.76 ? 427 ARG A CZ 1 ATOM 3520 N NH1 . ARG A 1 427 ? 42.897 70.132 -16.046 1.00 9.37 ? 427 ARG A NH1 1 ATOM 3521 N NH2 . ARG A 1 427 ? 43.962 71.916 -17.036 1.00 10.17 ? 427 ARG A NH2 1 ATOM 3522 N N . MET A 1 428 ? 42.220 72.380 -10.197 1.00 5.65 ? 428 MET A N 1 ATOM 3523 C CA . MET A 1 428 ? 43.586 72.439 -9.709 1.00 6.16 ? 428 MET A CA 1 ATOM 3524 C C . MET A 1 428 ? 44.066 71.068 -9.247 1.00 6.03 ? 428 MET A C 1 ATOM 3525 O O . MET A 1 428 ? 45.239 70.743 -9.433 1.00 5.99 ? 428 MET A O 1 ATOM 3526 C CB . MET A 1 428 ? 43.653 73.459 -8.555 1.00 7.39 ? 428 MET A CB 1 ATOM 3527 C CG . MET A 1 428 ? 45.062 73.856 -8.162 1.00 6.96 ? 428 MET A CG 1 ATOM 3528 S SD . MET A 1 428 ? 44.956 75.144 -6.877 1.00 9.92 ? 428 MET A SD 1 ATOM 3529 C CE . MET A 1 428 ? 46.668 75.696 -6.769 1.00 9.26 ? 428 MET A CE 1 ATOM 3530 N N . ASP A 1 429 ? 43.188 70.245 -8.660 1.00 6.26 ? 429 ASP A N 1 ATOM 3531 C CA . ASP A 1 429 ? 43.540 68.888 -8.263 1.00 5.79 ? 429 ASP A CA 1 ATOM 3532 C C . ASP A 1 429 ? 44.125 68.108 -9.434 1.00 5.35 ? 429 ASP A C 1 ATOM 3533 O O . ASP A 1 429 ? 45.129 67.392 -9.256 1.00 5.66 ? 429 ASP A O 1 ATOM 3534 C CB . ASP A 1 429 ? 42.293 68.167 -7.744 1.00 6.78 ? 429 ASP A CB 1 ATOM 3535 C CG . ASP A 1 429 ? 42.558 66.723 -7.467 1.00 6.97 ? 429 ASP A CG 1 ATOM 3536 O OD1 . ASP A 1 429 ? 43.054 66.459 -6.350 1.00 7.71 ? 429 ASP A OD1 1 ATOM 3537 O OD2 . ASP A 1 429 ? 42.266 65.805 -8.277 1.00 7.12 ? 429 ASP A OD2 1 ATOM 3538 N N . ARG A 1 430 ? 43.489 68.217 -10.612 1.00 4.74 ? 430 ARG A N 1 ATOM 3539 C CA . ARG A 1 430 ? 43.925 67.418 -11.737 1.00 5.05 ? 430 ARG A CA 1 ATOM 3540 C C . ARG A 1 430 ? 45.220 67.973 -12.305 1.00 4.38 ? 430 ARG A C 1 ATOM 3541 O O . ARG A 1 430 ? 46.072 67.228 -12.781 1.00 5.65 ? 430 ARG A O 1 ATOM 3542 C CB . ARG A 1 430 ? 42.852 67.414 -12.819 1.00 5.34 ? 430 ARG A CB 1 ATOM 3543 C CG . ARG A 1 430 ? 41.610 66.677 -12.413 1.00 5.25 ? 430 ARG A CG 1 ATOM 3544 C CD . ARG A 1 430 ? 41.871 65.229 -12.002 1.00 5.64 ? 430 ARG A CD 1 ATOM 3545 N NE . ARG A 1 430 ? 40.623 64.465 -12.039 1.00 6.06 ? 430 ARG A NE 1 ATOM 3546 C CZ . ARG A 1 430 ? 39.941 64.094 -10.958 1.00 5.54 ? 430 ARG A CZ 1 ATOM 3547 N NH1 . ARG A 1 430 ? 40.329 64.441 -9.733 1.00 5.65 ? 430 ARG A NH1 1 ATOM 3548 N NH2 . ARG A 1 430 ? 38.820 63.374 -11.113 1.00 6.11 ? 430 ARG A NH2 1 ATOM 3549 N N . VAL A 1 431 ? 45.411 69.284 -12.236 1.00 4.93 ? 431 VAL A N 1 ATOM 3550 C CA . VAL A 1 431 ? 46.686 69.873 -12.686 1.00 5.06 ? 431 VAL A CA 1 ATOM 3551 C C . VAL A 1 431 ? 47.823 69.399 -11.788 1.00 6.77 ? 431 VAL A C 1 ATOM 3552 O O . VAL A 1 431 ? 48.855 68.947 -12.261 1.00 5.55 ? 431 VAL A O 1 ATOM 3553 C CB . VAL A 1 431 ? 46.567 71.421 -12.694 1.00 5.48 ? 431 VAL A CB 1 ATOM 3554 C CG1 . VAL A 1 431 ? 47.920 72.047 -13.006 1.00 7.11 ? 431 VAL A CG1 1 ATOM 3555 C CG2 . VAL A 1 431 ? 45.495 71.877 -13.700 1.00 5.96 ? 431 VAL A CG2 1 ATOM 3556 N N . LEU A 1 432 ? 47.618 69.467 -10.496 1.00 5.11 ? 432 LEU A N 1 ATOM 3557 C CA . LEU A 1 432 ? 48.661 69.058 -9.575 1.00 5.07 ? 432 LEU A CA 1 ATOM 3558 C C . LEU A 1 432 ? 48.884 67.554 -9.676 1.00 4.67 ? 432 LEU A C 1 ATOM 3559 O O . LEU A 1 432 ? 50.032 67.085 -9.587 1.00 5.98 ? 432 LEU A O 1 ATOM 3560 C CB . LEU A 1 432 ? 48.299 69.476 -8.162 1.00 5.91 ? 432 LEU A CB 1 ATOM 3561 C CG . LEU A 1 432 ? 49.295 69.100 -7.077 1.00 5.93 ? 432 LEU A CG 1 ATOM 3562 C CD1 . LEU A 1 432 ? 50.701 69.679 -7.345 1.00 6.97 ? 432 LEU A CD1 1 ATOM 3563 C CD2 . LEU A 1 432 ? 48.802 69.653 -5.763 1.00 6.32 ? 432 LEU A CD2 1 ATOM 3564 N N . MET A 1 433 ? 47.816 66.771 -9.877 1.00 4.78 ? 433 MET A N 1 ATOM 3565 C CA . MET A 1 433 ? 47.992 65.326 -10.072 1.00 5.27 ? 433 MET A CA 1 ATOM 3566 C C . MET A 1 433 ? 49.054 65.023 -11.137 1.00 4.51 ? 433 MET A C 1 ATOM 3567 O O . MET A 1 433 ? 49.914 64.183 -10.986 1.00 5.34 ? 433 MET A O 1 ATOM 3568 C CB . MET A 1 433 ? 46.656 64.730 -10.553 1.00 5.73 ? 433 MET A CB 1 ATOM 3569 C CG . MET A 1 433 ? 46.727 63.235 -10.826 1.00 7.06 ? 433 MET A CG 1 ATOM 3570 S SD . MET A 1 433 ? 45.175 62.552 -11.508 1.00 10.05 ? 433 MET A SD 1 ATOM 3571 C CE . MET A 1 433 ? 45.204 63.264 -13.090 1.00 10.25 ? 433 MET A CE 1 ATOM 3572 N N . HIS A 1 434 ? 48.903 65.703 -12.264 1.00 4.73 ? 434 HIS A N 1 ATOM 3573 C CA . HIS A 1 434 ? 49.812 65.489 -13.367 1.00 5.09 ? 434 HIS A CA 1 ATOM 3574 C C . HIS A 1 434 ? 51.224 65.976 -13.057 1.00 4.97 ? 434 HIS A C 1 ATOM 3575 O O . HIS A 1 434 ? 52.215 65.321 -13.397 1.00 5.39 ? 434 HIS A O 1 ATOM 3576 C CB . HIS A 1 434 ? 49.276 66.186 -14.621 1.00 6.26 ? 434 HIS A CB 1 ATOM 3577 C CG . HIS A 1 434 ? 50.300 66.220 -15.720 1.00 6.53 ? 434 HIS A CG 1 ATOM 3578 N ND1 . HIS A 1 434 ? 50.637 65.103 -16.454 1.00 8.84 ? 434 HIS A ND1 1 ATOM 3579 C CD2 . HIS A 1 434 ? 51.155 67.201 -16.088 1.00 9.45 ? 434 HIS A CD2 1 ATOM 3580 C CE1 . HIS A 1 434 ? 51.637 65.412 -17.271 1.00 8.55 ? 434 HIS A CE1 1 ATOM 3581 N NE2 . HIS A 1 434 ? 51.956 66.680 -17.081 1.00 8.76 ? 434 HIS A NE2 1 ATOM 3582 N N A TYR A 1 435 ? 51.298 67.144 -12.407 0.50 4.92 ? 435 TYR A N 1 ATOM 3583 N N B TYR A 1 435 ? 51.325 67.121 -12.416 0.50 3.95 ? 435 TYR A N 1 ATOM 3584 C CA A TYR A 1 435 ? 52.588 67.750 -12.019 0.60 5.65 ? 435 TYR A CA 1 ATOM 3585 C CA B TYR A 1 435 ? 52.639 67.650 -12.110 0.40 3.81 ? 435 TYR A CA 1 ATOM 3586 C C A TYR A 1 435 ? 53.370 66.875 -11.051 0.50 5.69 ? 435 TYR A C 1 ATOM 3587 C C B TYR A 1 435 ? 53.390 66.827 -11.067 0.50 4.63 ? 435 TYR A C 1 ATOM 3588 O O A TYR A 1 435 ? 54.598 66.820 -11.126 0.50 5.20 ? 435 TYR A O 1 ATOM 3589 O O B TYR A 1 435 ? 54.583 66.708 -11.149 0.50 4.53 ? 435 TYR A O 1 ATOM 3590 C CB A TYR A 1 435 ? 52.387 69.166 -11.409 0.60 7.44 ? 435 TYR A CB 1 ATOM 3591 C CB B TYR A 1 435 ? 52.557 69.145 -11.794 0.40 4.03 ? 435 TYR A CB 1 ATOM 3592 C CG A TYR A 1 435 ? 52.339 70.272 -12.437 0.60 9.39 ? 435 TYR A CG 1 ATOM 3593 C CG B TYR A 1 435 ? 52.428 69.973 -13.062 0.40 4.08 ? 435 TYR A CG 1 ATOM 3594 C CD1 A TYR A 1 435 ? 51.510 70.164 -13.555 0.60 8.50 ? 435 TYR A CD1 1 ATOM 3595 C CD1 B TYR A 1 435 ? 53.351 69.863 -14.089 0.40 4.77 ? 435 TYR A CD1 1 ATOM 3596 C CD2 A TYR A 1 435 ? 53.099 71.437 -12.289 0.60 12.79 ? 435 TYR A CD2 1 ATOM 3597 C CD2 B TYR A 1 435 ? 51.380 70.809 -13.250 0.40 3.86 ? 435 TYR A CD2 1 ATOM 3598 C CE1 A TYR A 1 435 ? 51.458 71.159 -14.538 0.60 12.18 ? 435 TYR A CE1 1 ATOM 3599 C CE1 B TYR A 1 435 ? 53.242 70.625 -15.255 0.40 5.80 ? 435 TYR A CE1 1 ATOM 3600 C CE2 A TYR A 1 435 ? 53.056 72.448 -13.253 0.60 14.46 ? 435 TYR A CE2 1 ATOM 3601 C CE2 B TYR A 1 435 ? 51.266 71.577 -14.390 0.40 2.75 ? 435 TYR A CE2 1 ATOM 3602 C CZ A TYR A 1 435 ? 52.231 72.299 -14.377 0.60 10.74 ? 435 TYR A CZ 1 ATOM 3603 C CZ B TYR A 1 435 ? 52.189 71.472 -15.381 0.40 3.66 ? 435 TYR A CZ 1 ATOM 3604 O OH A TYR A 1 435 ? 52.182 73.278 -15.356 0.60 14.33 ? 435 TYR A OH 1 ATOM 3605 O OH B TYR A 1 435 ? 52.049 72.234 -16.520 0.40 4.90 ? 435 TYR A OH 1 ATOM 3606 N N . VAL A 1 436 ? 52.666 66.194 -10.158 1.00 4.76 ? 436 VAL A N 1 ATOM 3607 C CA . VAL A 1 436 ? 53.322 65.288 -9.211 1.00 4.65 ? 436 VAL A CA 1 ATOM 3608 C C . VAL A 1 436 ? 53.836 64.074 -9.974 1.00 4.87 ? 436 VAL A C 1 ATOM 3609 O O . VAL A 1 436 ? 55.001 63.678 -9.805 1.00 5.24 ? 436 VAL A O 1 ATOM 3610 C CB . VAL A 1 436 ? 52.371 64.902 -8.086 1.00 4.66 ? 436 VAL A CB 1 ATOM 3611 C CG1 . VAL A 1 436 ? 52.869 63.664 -7.316 1.00 6.47 ? 436 VAL A CG1 1 ATOM 3612 C CG2 . VAL A 1 436 ? 52.169 66.087 -7.146 1.00 5.37 ? 436 VAL A CG2 1 ATOM 3613 N N . ARG A 1 437 ? 53.016 63.514 -10.847 1.00 4.83 ? 437 ARG A N 1 ATOM 3614 C CA . ARG A 1 437 ? 53.467 62.357 -11.619 1.00 5.07 ? 437 ARG A CA 1 ATOM 3615 C C . ARG A 1 437 ? 54.706 62.728 -12.428 1.00 5.71 ? 437 ARG A C 1 ATOM 3616 O O . ARG A 1 437 ? 55.696 61.969 -12.488 1.00 5.73 ? 437 ARG A O 1 ATOM 3617 C CB . ARG A 1 437 ? 52.382 61.865 -12.559 1.00 5.43 ? 437 ARG A CB 1 ATOM 3618 C CG . ARG A 1 437 ? 52.885 60.835 -13.582 1.00 8.20 ? 437 ARG A CG 1 ATOM 3619 C CD . ARG A 1 437 ? 51.777 60.406 -14.489 1.00 9.35 ? 437 ARG A CD 1 ATOM 3620 N NE . ARG A 1 437 ? 52.309 59.673 -15.627 1.00 7.85 ? 437 ARG A NE 1 ATOM 3621 C CZ . ARG A 1 437 ? 51.587 58.849 -16.346 1.00 9.41 ? 437 ARG A CZ 1 ATOM 3622 N NH1 . ARG A 1 437 ? 50.310 58.584 -16.019 1.00 9.33 ? 437 ARG A NH1 1 ATOM 3623 N NH2 . ARG A 1 437 ? 52.148 58.253 -17.383 1.00 8.13 ? 437 ARG A NH2 1 ATOM 3624 N N . ALA A 1 438 ? 54.656 63.877 -13.117 1.00 4.81 ? 438 ALA A N 1 ATOM 3625 C CA . ALA A 1 438 ? 55.767 64.265 -13.978 1.00 5.73 ? 438 ALA A CA 1 ATOM 3626 C C . ALA A 1 438 ? 57.034 64.548 -13.174 1.00 5.15 ? 438 ALA A C 1 ATOM 3627 O O . ALA A 1 438 ? 58.129 64.192 -13.629 1.00 6.17 ? 438 ALA A O 1 ATOM 3628 C CB . ALA A 1 438 ? 55.383 65.477 -14.819 1.00 6.33 ? 438 ALA A CB 1 ATOM 3629 N N . ALA A 1 439 ? 56.913 65.237 -12.026 1.00 5.29 ? 439 ALA A N 1 ATOM 3630 C CA . ALA A 1 439 ? 58.075 65.533 -11.198 1.00 5.80 ? 439 ALA A CA 1 ATOM 3631 C C . ALA A 1 439 ? 58.691 64.249 -10.658 1.00 5.73 ? 439 ALA A C 1 ATOM 3632 O O . ALA A 1 439 ? 59.923 64.112 -10.622 1.00 6.05 ? 439 ALA A O 1 ATOM 3633 C CB . ALA A 1 439 ? 57.711 66.455 -10.086 1.00 5.71 ? 439 ALA A CB 1 ATOM 3634 N N . GLU A 1 440 ? 57.858 63.312 -10.202 1.00 5.50 ? 440 GLU A N 1 ATOM 3635 C CA . GLU A 1 440 ? 58.408 62.062 -9.686 1.00 6.17 ? 440 GLU A CA 1 ATOM 3636 C C . GLU A 1 440 ? 59.081 61.275 -10.809 1.00 5.40 ? 440 GLU A C 1 ATOM 3637 O O . GLU A 1 440 ? 60.133 60.663 -10.584 1.00 6.40 ? 440 GLU A O 1 ATOM 3638 C CB . GLU A 1 440 ? 57.324 61.217 -8.986 1.00 7.14 ? 440 GLU A CB 1 ATOM 3639 C CG . GLU A 1 440 ? 56.779 61.844 -7.724 1.00 8.15 ? 440 GLU A CG 1 ATOM 3640 C CD . GLU A 1 440 ? 56.114 60.842 -6.819 1.00 12.60 ? 440 GLU A CD 1 ATOM 3641 O OE1 . GLU A 1 440 ? 55.006 60.369 -7.138 1.00 12.65 ? 440 GLU A OE1 1 ATOM 3642 O OE2 . GLU A 1 440 ? 56.717 60.550 -5.784 1.00 12.53 ? 440 GLU A OE2 1 ATOM 3643 N N . MET A 1 441 ? 58.474 61.227 -11.988 1.00 5.16 ? 441 MET A N 1 ATOM 3644 C CA . MET A 1 441 ? 59.041 60.472 -13.095 1.00 5.64 ? 441 MET A CA 1 ATOM 3645 C C . MET A 1 441 ? 60.339 61.109 -13.621 1.00 5.81 ? 441 MET A C 1 ATOM 3646 O O . MET A 1 441 ? 61.370 60.412 -13.724 1.00 6.58 ? 441 MET A O 1 ATOM 3647 C CB . MET A 1 441 ? 58.003 60.340 -14.225 1.00 6.84 ? 441 MET A CB 1 ATOM 3648 C CG . MET A 1 441 ? 58.542 59.604 -15.435 1.00 7.60 ? 441 MET A CG 1 ATOM 3649 S SD . MET A 1 441 ? 57.272 59.410 -16.727 1.00 8.08 ? 441 MET A SD 1 ATOM 3650 C CE . MET A 1 441 ? 56.147 58.221 -15.855 1.00 9.29 ? 441 MET A CE 1 ATOM 3651 N N . LEU A 1 442 ? 60.315 62.412 -13.884 1.00 4.97 ? 442 LEU A N 1 ATOM 3652 C CA . LEU A 1 442 ? 61.503 63.085 -14.395 1.00 6.85 ? 442 LEU A CA 1 ATOM 3653 C C . LEU A 1 442 ? 62.683 62.961 -13.473 1.00 6.78 ? 442 LEU A C 1 ATOM 3654 O O . LEU A 1 442 ? 63.836 62.814 -13.918 1.00 7.49 ? 442 LEU A O 1 ATOM 3655 C CB . LEU A 1 442 ? 61.206 64.560 -14.659 1.00 6.46 ? 442 LEU A CB 1 ATOM 3656 C CG . LEU A 1 442 ? 60.586 64.806 -16.045 1.00 6.87 ? 442 LEU A CG 1 ATOM 3657 C CD1 . LEU A 1 442 ? 59.917 66.158 -16.086 1.00 9.30 ? 442 LEU A CD1 1 ATOM 3658 C CD2 . LEU A 1 442 ? 61.685 64.729 -17.128 1.00 8.81 ? 442 LEU A CD2 1 ATOM 3659 N N . SER A 1 443 ? 62.438 63.055 -12.170 1.00 4.82 ? 443 SER A N 1 ATOM 3660 C CA . SER A 1 443 ? 63.540 62.992 -11.223 1.00 6.26 ? 443 SER A CA 1 ATOM 3661 C C . SER A 1 443 ? 63.947 61.583 -10.876 1.00 7.18 ? 443 SER A C 1 ATOM 3662 O O . SER A 1 443 ? 65.073 61.411 -10.370 1.00 8.08 ? 443 SER A O 1 ATOM 3663 C CB . SER A 1 443 ? 63.267 63.801 -9.978 1.00 6.98 ? 443 SER A CB 1 ATOM 3664 O OG . SER A 1 443 ? 62.176 63.257 -9.246 1.00 7.02 ? 443 SER A OG 1 ATOM 3665 N N . ALA A 1 444 ? 63.136 60.581 -11.219 1.00 5.58 ? 444 ALA A N 1 ATOM 3666 C CA . ALA A 1 444 ? 63.444 59.185 -10.903 1.00 7.56 ? 444 ALA A CA 1 ATOM 3667 C C . ALA A 1 444 ? 64.628 58.667 -11.674 1.00 7.99 ? 444 ALA A C 1 ATOM 3668 O O . ALA A 1 444 ? 65.251 57.673 -11.249 1.00 9.07 ? 444 ALA A O 1 ATOM 3669 C CB . ALA A 1 444 ? 62.217 58.308 -11.214 1.00 7.10 ? 444 ALA A CB 1 ATOM 3670 N N . TRP A 1 445 ? 64.889 59.243 -12.844 1.00 7.87 ? 445 TRP A N 1 ATOM 3671 C CA . TRP A 1 445 ? 65.942 58.709 -13.717 1.00 8.51 ? 445 TRP A CA 1 ATOM 3672 C C . TRP A 1 445 ? 67.344 58.769 -13.124 1.00 8.43 ? 445 TRP A C 1 ATOM 3673 O O . TRP A 1 445 ? 68.195 57.961 -13.502 1.00 10.31 ? 445 TRP A O 1 ATOM 3674 C CB . TRP A 1 445 ? 65.945 59.479 -15.045 1.00 8.68 ? 445 TRP A CB 1 ATOM 3675 C CG . TRP A 1 445 ? 64.663 59.293 -15.844 1.00 6.23 ? 445 TRP A CG 1 ATOM 3676 C CD1 . TRP A 1 445 ? 63.660 60.233 -16.008 1.00 7.34 ? 445 TRP A CD1 1 ATOM 3677 C CD2 . TRP A 1 445 ? 64.216 58.114 -16.510 1.00 6.12 ? 445 TRP A CD2 1 ATOM 3678 N NE1 . TRP A 1 445 ? 62.642 59.695 -16.755 1.00 6.96 ? 445 TRP A NE1 1 ATOM 3679 C CE2 . TRP A 1 445 ? 62.950 58.396 -17.074 1.00 5.73 ? 445 TRP A CE2 1 ATOM 3680 C CE3 . TRP A 1 445 ? 64.760 56.839 -16.722 1.00 8.22 ? 445 TRP A CE3 1 ATOM 3681 C CZ2 . TRP A 1 445 ? 62.248 57.473 -17.832 1.00 7.48 ? 445 TRP A CZ2 1 ATOM 3682 C CZ3 . TRP A 1 445 ? 64.048 55.919 -17.489 1.00 9.00 ? 445 TRP A CZ3 1 ATOM 3683 C CH2 . TRP A 1 445 ? 62.811 56.235 -18.023 1.00 8.52 ? 445 TRP A CH2 1 ATOM 3684 N N . HIS A 1 446 ? 67.546 59.705 -12.198 1.00 8.42 ? 446 HIS A N 1 ATOM 3685 C CA . HIS A 1 446 ? 68.824 59.863 -11.535 1.00 10.77 ? 446 HIS A CA 1 ATOM 3686 C C . HIS A 1 446 ? 68.675 59.752 -10.042 1.00 10.15 ? 446 HIS A C 1 ATOM 3687 O O . HIS A 1 446 ? 67.621 60.001 -9.489 1.00 9.61 ? 446 HIS A O 1 ATOM 3688 C CB . HIS A 1 446 ? 69.399 61.249 -11.788 1.00 11.10 ? 446 HIS A CB 1 ATOM 3689 C CG . HIS A 1 446 ? 69.821 61.484 -13.199 1.00 13.74 ? 446 HIS A CG 1 ATOM 3690 N ND1 . HIS A 1 446 ? 69.032 62.158 -14.107 1.00 17.71 ? 446 HIS A ND1 1 ATOM 3691 C CD2 . HIS A 1 446 ? 70.959 61.150 -13.855 1.00 17.19 ? 446 HIS A CD2 1 ATOM 3692 C CE1 . HIS A 1 446 ? 69.659 62.222 -15.265 1.00 20.42 ? 446 HIS A CE1 1 ATOM 3693 N NE2 . HIS A 1 446 ? 70.825 61.615 -15.145 1.00 17.53 ? 446 HIS A NE2 1 ATOM 3694 N N . SER A 1 447 ? 69.798 59.432 -9.394 1.00 11.47 ? 447 SER A N 1 ATOM 3695 C CA A SER A 1 447 ? 69.985 59.642 -7.987 0.50 11.05 ? 447 SER A CA 1 ATOM 3696 C CA B SER A 1 447 ? 69.971 59.663 -7.964 0.50 11.18 ? 447 SER A CA 1 ATOM 3697 C C . SER A 1 447 ? 70.425 61.092 -7.762 1.00 11.49 ? 447 SER A C 1 ATOM 3698 O O . SER A 1 447 ? 71.255 61.621 -8.545 1.00 12.65 ? 447 SER A O 1 ATOM 3699 C CB A SER A 1 447 ? 71.076 58.695 -7.525 0.50 12.78 ? 447 SER A CB 1 ATOM 3700 C CB B SER A 1 447 ? 71.022 58.734 -7.357 0.50 12.86 ? 447 SER A CB 1 ATOM 3701 O OG A SER A 1 447 ? 71.006 58.543 -6.141 0.50 11.70 ? 447 SER A OG 1 ATOM 3702 O OG B SER A 1 447 ? 70.433 57.594 -6.773 0.50 12.74 ? 447 SER A OG 1 ATOM 3703 N N . TRP A 1 448 ? 69.893 61.743 -6.742 1.00 9.95 ? 448 TRP A N 1 ATOM 3704 C CA . TRP A 1 448 ? 70.234 63.135 -6.528 1.00 11.23 ? 448 TRP A CA 1 ATOM 3705 C C . TRP A 1 448 ? 70.940 63.336 -5.203 1.00 12.32 ? 448 TRP A C 1 ATOM 3706 O O . TRP A 1 448 ? 70.538 62.764 -4.191 1.00 12.45 ? 448 TRP A O 1 ATOM 3707 C CB . TRP A 1 448 ? 68.966 63.995 -6.559 1.00 9.66 ? 448 TRP A CB 1 ATOM 3708 C CG . TRP A 1 448 ? 68.324 64.037 -7.905 1.00 9.62 ? 448 TRP A CG 1 ATOM 3709 C CD1 . TRP A 1 448 ? 67.459 63.123 -8.414 1.00 9.80 ? 448 TRP A CD1 1 ATOM 3710 C CD2 . TRP A 1 448 ? 68.495 65.045 -8.904 1.00 9.37 ? 448 TRP A CD2 1 ATOM 3711 N NE1 . TRP A 1 448 ? 67.077 63.486 -9.679 1.00 9.21 ? 448 TRP A NE1 1 ATOM 3712 C CE2 . TRP A 1 448 ? 67.672 64.685 -9.997 1.00 7.99 ? 448 TRP A CE2 1 ATOM 3713 C CE3 . TRP A 1 448 ? 69.242 66.237 -8.980 1.00 10.67 ? 448 TRP A CE3 1 ATOM 3714 C CZ2 . TRP A 1 448 ? 67.607 65.437 -11.159 1.00 10.27 ? 448 TRP A CZ2 1 ATOM 3715 C CZ3 . TRP A 1 448 ? 69.146 67.004 -10.133 1.00 9.15 ? 448 TRP A CZ3 1 ATOM 3716 C CH2 . TRP A 1 448 ? 68.337 66.584 -11.212 1.00 10.59 ? 448 TRP A CH2 1 ATOM 3717 N N . ASP A 1 449 ? 71.989 64.166 -5.206 1.00 14.46 ? 449 ASP A N 1 ATOM 3718 C CA . ASP A 1 449 ? 72.605 64.601 -3.970 1.00 15.82 ? 449 ASP A CA 1 ATOM 3719 C C . ASP A 1 449 ? 71.548 65.222 -3.051 1.00 15.27 ? 449 ASP A C 1 ATOM 3720 O O . ASP A 1 449 ? 70.641 65.898 -3.524 1.00 14.17 ? 449 ASP A O 1 ATOM 3721 C CB . ASP A 1 449 ? 73.671 65.653 -4.274 1.00 17.75 ? 449 ASP A CB 1 ATOM 3722 C CG . ASP A 1 449 ? 74.482 66.003 -3.058 1.00 21.17 ? 449 ASP A CG 1 ATOM 3723 O OD1 . ASP A 1 449 ? 75.432 65.244 -2.746 1.00 28.88 ? 449 ASP A OD1 1 ATOM 3724 O OD2 . ASP A 1 449 ? 74.234 66.984 -2.332 1.00 23.41 ? 449 ASP A OD2 1 ATOM 3725 N N . GLY A 1 450 ? 71.697 65.060 -1.740 1.00 15.46 ? 450 GLY A N 1 ATOM 3726 C CA . GLY A 1 450 ? 70.772 65.657 -0.788 1.00 16.18 ? 450 GLY A CA 1 ATOM 3727 C C . GLY A 1 450 ? 70.653 67.166 -0.875 1.00 15.88 ? 450 GLY A C 1 ATOM 3728 O O . GLY A 1 450 ? 69.604 67.747 -0.540 1.00 16.04 ? 450 GLY A O 1 ATOM 3729 N N . MET A 1 451 ? 71.711 67.824 -1.359 1.00 15.75 ? 451 MET A N 1 ATOM 3730 C CA . MET A 1 451 ? 71.688 69.273 -1.486 1.00 16.42 ? 451 MET A CA 1 ATOM 3731 C C . MET A 1 451 ? 70.692 69.770 -2.535 1.00 15.04 ? 451 MET A C 1 ATOM 3732 O O . MET A 1 451 ? 70.314 70.946 -2.534 1.00 16.07 ? 451 MET A O 1 ATOM 3733 C CB . MET A 1 451 ? 73.091 69.818 -1.797 1.00 17.84 ? 451 MET A CB 1 ATOM 3734 C CG . MET A 1 451 ? 74.078 69.681 -0.641 1.00 22.52 ? 451 MET A CG 1 ATOM 3735 S SD . MET A 1 451 ? 73.514 70.562 0.840 1.00 35.43 ? 451 MET A SD 1 ATOM 3736 C CE . MET A 1 451 ? 73.446 72.290 0.203 1.00 32.99 ? 451 MET A CE 1 ATOM 3737 N N . ALA A 1 452 ? 70.258 68.871 -3.427 1.00 13.35 ? 452 ALA A N 1 ATOM 3738 C CA . ALA A 1 452 ? 69.325 69.239 -4.489 1.00 13.07 ? 452 ALA A CA 1 ATOM 3739 C C . ALA A 1 452 ? 67.897 69.362 -3.944 1.00 12.86 ? 452 ALA A C 1 ATOM 3740 O O . ALA A 1 452 ? 67.046 69.975 -4.591 1.00 13.54 ? 452 ALA A O 1 ATOM 3741 C CB . ALA A 1 452 ? 69.360 68.237 -5.631 1.00 12.93 ? 452 ALA A CB 1 ATOM 3742 N N . ARG A 1 453 ? 67.666 68.794 -2.752 1.00 11.85 ? 453 ARG A N 1 ATOM 3743 C CA . ARG A 1 453 ? 66.378 68.911 -2.046 1.00 11.92 ? 453 ARG A CA 1 ATOM 3744 C C . ARG A 1 453 ? 65.245 68.311 -2.857 1.00 11.22 ? 453 ARG A C 1 ATOM 3745 O O . ARG A 1 453 ? 64.095 68.740 -2.728 1.00 12.10 ? 453 ARG A O 1 ATOM 3746 C CB . ARG A 1 453 ? 66.065 70.361 -1.695 1.00 12.59 ? 453 ARG A CB 1 ATOM 3747 C CG . ARG A 1 453 ? 67.121 70.991 -0.821 1.00 15.09 ? 453 ARG A CG 1 ATOM 3748 C CD . ARG A 1 453 ? 66.908 72.474 -0.619 1.00 18.97 ? 453 ARG A CD 1 ATOM 3749 N NE . ARG A 1 453 ? 65.736 72.730 0.209 1.00 20.16 ? 453 ARG A NE 1 ATOM 3750 C CZ . ARG A 1 453 ? 65.216 73.939 0.390 1.00 21.16 ? 453 ARG A CZ 1 ATOM 3751 N NH1 . ARG A 1 453 ? 65.757 75.006 -0.216 1.00 21.72 ? 453 ARG A NH1 1 ATOM 3752 N NH2 . ARG A 1 453 ? 64.148 74.080 1.156 1.00 23.05 ? 453 ARG A NH2 1 ATOM 3753 N N . ILE A 1 454 ? 65.542 67.311 -3.675 1.00 9.12 ? 454 ILE A N 1 ATOM 3754 C CA . ILE A 1 454 ? 64.520 66.701 -4.524 1.00 9.21 ? 454 ILE A CA 1 ATOM 3755 C C . ILE A 1 454 ? 63.532 65.934 -3.650 1.00 9.53 ? 454 ILE A C 1 ATOM 3756 O O . ILE A 1 454 ? 62.311 66.101 -3.797 1.00 9.10 ? 454 ILE A O 1 ATOM 3757 C CB . ILE A 1 454 ? 65.183 65.769 -5.552 1.00 9.86 ? 454 ILE A CB 1 ATOM 3758 C CG1 . ILE A 1 454 ? 66.138 66.547 -6.479 1.00 11.14 ? 454 ILE A CG1 1 ATOM 3759 C CG2 . ILE A 1 454 ? 64.152 64.955 -6.320 1.00 10.89 ? 454 ILE A CG2 1 ATOM 3760 C CD1 . ILE A 1 454 ? 65.481 67.523 -7.395 1.00 12.01 ? 454 ILE A CD1 1 ATOM 3761 N N . GLU A 1 455 ? 64.009 65.078 -2.764 1.00 9.33 ? 455 GLU A N 1 ATOM 3762 C CA . GLU A 1 455 ? 63.092 64.292 -1.932 1.00 9.67 ? 455 GLU A CA 1 ATOM 3763 C C . GLU A 1 455 ? 62.233 65.184 -1.065 1.00 9.55 ? 455 GLU A C 1 ATOM 3764 O O . GLU A 1 455 ? 61.029 64.914 -0.913 1.00 8.91 ? 455 GLU A O 1 ATOM 3765 C CB . GLU A 1 455 ? 63.867 63.309 -1.040 1.00 10.55 ? 455 GLU A CB 1 ATOM 3766 C CG . GLU A 1 455 ? 64.471 62.137 -1.803 1.00 12.79 ? 455 GLU A CG 1 ATOM 3767 C CD . GLU A 1 455 ? 65.856 62.434 -2.416 1.00 15.13 ? 455 GLU A CD 1 ATOM 3768 O OE1 . GLU A 1 455 ? 66.341 63.596 -2.281 1.00 14.70 ? 455 GLU A OE1 1 ATOM 3769 O OE2 . GLU A 1 455 ? 66.418 61.493 -3.013 1.00 12.83 ? 455 GLU A OE2 1 ATOM 3770 N N . GLU A 1 456 ? 62.790 66.255 -0.518 1.00 9.78 ? 456 GLU A N 1 ATOM 3771 C CA . GLU A 1 456 ? 62.047 67.204 0.280 1.00 11.15 ? 456 GLU A CA 1 ATOM 3772 C C . GLU A 1 456 ? 60.915 67.824 -0.547 1.00 9.71 ? 456 GLU A C 1 ATOM 3773 O O . GLU A 1 456 ? 59.770 67.918 -0.073 1.00 10.15 ? 456 GLU A O 1 ATOM 3774 C CB . GLU A 1 456 ? 62.989 68.317 0.768 1.00 11.93 ? 456 GLU A CB 1 ATOM 3775 C CG . GLU A 1 456 ? 62.354 69.443 1.541 1.00 15.58 ? 456 GLU A CG 1 ATOM 3776 C CD . GLU A 1 456 ? 63.303 70.621 1.732 1.00 16.81 ? 456 GLU A CD 1 ATOM 3777 O OE1 . GLU A 1 456 ? 64.533 70.453 1.523 1.00 21.61 ? 456 GLU A OE1 1 ATOM 3778 O OE2 . GLU A 1 456 ? 62.817 71.716 2.099 1.00 22.76 ? 456 GLU A OE2 1 ATOM 3779 N N . ARG A 1 457 ? 61.220 68.320 -1.743 1.00 7.90 ? 457 ARG A N 1 ATOM 3780 C CA . ARG A 1 457 ? 60.182 68.994 -2.552 1.00 7.63 ? 457 ARG A CA 1 ATOM 3781 C C . ARG A 1 457 ? 59.118 68.002 -2.999 1.00 7.95 ? 457 ARG A C 1 ATOM 3782 O O . ARG A 1 457 ? 57.933 68.336 -2.997 1.00 7.36 ? 457 ARG A O 1 ATOM 3783 C CB . ARG A 1 457 ? 60.804 69.714 -3.766 1.00 7.35 ? 457 ARG A CB 1 ATOM 3784 C CG . ARG A 1 457 ? 61.152 71.156 -3.513 1.00 11.41 ? 457 ARG A CG 1 ATOM 3785 C CD . ARG A 1 457 ? 62.149 71.412 -2.418 1.00 13.70 ? 457 ARG A CD 1 ATOM 3786 N NE . ARG A 1 457 ? 62.392 72.842 -2.170 1.00 14.04 ? 457 ARG A NE 1 ATOM 3787 C CZ . ARG A 1 457 ? 63.298 73.580 -2.798 1.00 18.53 ? 457 ARG A CZ 1 ATOM 3788 N NH1 . ARG A 1 457 ? 64.060 73.074 -3.774 1.00 17.16 ? 457 ARG A NH1 1 ATOM 3789 N NH2 . ARG A 1 457 ? 63.412 74.860 -2.458 1.00 20.43 ? 457 ARG A NH2 1 ATOM 3790 N N . LEU A 1 458 ? 59.503 66.773 -3.332 1.00 6.65 ? 458 LEU A N 1 ATOM 3791 C CA . LEU A 1 458 ? 58.510 65.786 -3.777 1.00 6.59 ? 458 LEU A CA 1 ATOM 3792 C C . LEU A 1 458 ? 57.649 65.376 -2.620 1.00 7.74 ? 458 LEU A C 1 ATOM 3793 O O . LEU A 1 458 ? 56.449 65.189 -2.812 1.00 8.19 ? 458 LEU A O 1 ATOM 3794 C CB . LEU A 1 458 ? 59.186 64.559 -4.363 1.00 5.98 ? 458 LEU A CB 1 ATOM 3795 C CG . LEU A 1 458 ? 59.886 64.827 -5.711 1.00 7.64 ? 458 LEU A CG 1 ATOM 3796 C CD1 . LEU A 1 458 ? 60.636 63.581 -6.112 1.00 9.73 ? 458 LEU A CD1 1 ATOM 3797 C CD2 . LEU A 1 458 ? 58.822 65.160 -6.773 1.00 9.57 ? 458 LEU A CD2 1 ATOM 3798 N N . GLU A 1 459 ? 58.223 65.239 -1.432 1.00 7.08 ? 459 GLU A N 1 ATOM 3799 C CA . GLU A 1 459 ? 57.398 64.828 -0.292 1.00 8.01 ? 459 GLU A CA 1 ATOM 3800 C C . GLU A 1 459 ? 56.366 65.908 0.020 1.00 8.08 ? 459 GLU A C 1 ATOM 3801 O O . GLU A 1 459 ? 55.191 65.620 0.260 1.00 7.37 ? 459 GLU A O 1 ATOM 3802 C CB . GLU A 1 459 ? 58.279 64.577 0.931 1.00 9.18 ? 459 GLU A CB 1 ATOM 3803 C CG . GLU A 1 459 ? 57.470 64.157 2.142 1.00 11.39 ? 459 GLU A CG 1 ATOM 3804 C CD . GLU A 1 459 ? 58.365 63.560 3.212 1.00 16.30 ? 459 GLU A CD 1 ATOM 3805 O OE1 . GLU A 1 459 ? 58.891 64.372 4.002 1.00 20.72 ? 459 GLU A OE1 1 ATOM 3806 O OE2 . GLU A 1 459 ? 58.539 62.308 3.257 1.00 20.09 ? 459 GLU A OE2 1 ATOM 3807 N N . GLN A 1 460 ? 56.766 67.173 -0.014 1.00 7.52 ? 460 GLN A N 1 ATOM 3808 C CA . GLN A 1 460 ? 55.832 68.290 0.190 1.00 9.15 ? 460 GLN A CA 1 ATOM 3809 C C . GLN A 1 460 ? 54.719 68.210 -0.854 1.00 7.97 ? 460 GLN A C 1 ATOM 3810 O O . GLN A 1 460 ? 53.519 68.334 -0.529 1.00 8.41 ? 460 GLN A O 1 ATOM 3811 C CB . GLN A 1 460 ? 56.582 69.621 0.053 1.00 10.59 ? 460 GLN A CB 1 ATOM 3812 C CG . GLN A 1 460 ? 55.697 70.867 0.167 1.00 14.59 ? 460 GLN A CG 1 ATOM 3813 C CD . GLN A 1 460 ? 56.444 72.156 -0.192 1.00 16.17 ? 460 GLN A CD 1 ATOM 3814 O OE1 . GLN A 1 460 ? 57.531 72.118 -0.769 1.00 26.13 ? 460 GLN A OE1 1 ATOM 3815 N NE2 . GLN A 1 460 ? 55.836 73.290 0.115 1.00 24.57 ? 460 GLN A NE2 1 ATOM 3816 N N . ALA A 1 461 ? 55.085 68.055 -2.135 1.00 6.86 ? 461 ALA A N 1 ATOM 3817 C CA . ALA A 1 461 ? 54.053 68.052 -3.165 1.00 6.35 ? 461 ALA A CA 1 ATOM 3818 C C . ALA A 1 461 ? 53.127 66.836 -2.978 1.00 6.52 ? 461 ALA A C 1 ATOM 3819 O O . ALA A 1 461 ? 51.914 67.001 -3.092 1.00 6.69 ? 461 ALA A O 1 ATOM 3820 C CB . ALA A 1 461 ? 54.693 68.036 -4.520 1.00 6.88 ? 461 ALA A CB 1 ATOM 3821 N N . ARG A 1 462 ? 53.663 65.642 -2.707 1.00 5.56 ? 462 ARG A N 1 ATOM 3822 C CA . ARG A 1 462 ? 52.777 64.484 -2.505 1.00 5.49 ? 462 ARG A CA 1 ATOM 3823 C C . ARG A 1 462 ? 51.841 64.720 -1.337 1.00 5.87 ? 462 ARG A C 1 ATOM 3824 O O . ARG A 1 462 ? 50.666 64.300 -1.391 1.00 6.10 ? 462 ARG A O 1 ATOM 3825 C CB . ARG A 1 462 ? 53.531 63.185 -2.225 1.00 5.81 ? 462 ARG A CB 1 ATOM 3826 C CG . ARG A 1 462 ? 54.241 62.637 -3.471 1.00 7.94 ? 462 ARG A CG 1 ATOM 3827 C CD . ARG A 1 462 ? 54.789 61.208 -3.239 1.00 6.74 ? 462 ARG A CD 1 ATOM 3828 N NE . ARG A 1 462 ? 55.668 61.160 -2.057 1.00 7.53 ? 462 ARG A NE 1 ATOM 3829 C CZ . ARG A 1 462 ? 56.986 61.318 -2.125 1.00 10.40 ? 462 ARG A CZ 1 ATOM 3830 N NH1 . ARG A 1 462 ? 57.575 61.477 -3.299 1.00 9.41 ? 462 ARG A NH1 1 ATOM 3831 N NH2 . ARG A 1 462 ? 57.712 61.284 -1.024 1.00 11.44 ? 462 ARG A NH2 1 ATOM 3832 N N . ARG A 1 463 ? 52.351 65.330 -0.269 1.00 6.42 ? 463 ARG A N 1 ATOM 3833 C CA . ARG A 1 463 ? 51.536 65.470 0.932 1.00 5.75 ? 463 ARG A CA 1 ATOM 3834 C C . ARG A 1 463 ? 50.458 66.501 0.757 1.00 6.90 ? 463 ARG A C 1 ATOM 3835 O O . ARG A 1 463 ? 49.345 66.313 1.260 1.00 7.07 ? 463 ARG A O 1 ATOM 3836 C CB . ARG A 1 463 ? 52.396 65.716 2.165 1.00 6.15 ? 463 ARG A CB 1 ATOM 3837 C CG . ARG A 1 463 ? 53.120 64.452 2.526 1.00 7.23 ? 463 ARG A CG 1 ATOM 3838 C CD . ARG A 1 463 ? 54.127 64.623 3.644 1.00 9.73 ? 463 ARG A CD 1 ATOM 3839 N NE . ARG A 1 463 ? 54.655 63.312 4.001 1.00 9.99 ? 463 ARG A NE 1 ATOM 3840 C CZ . ARG A 1 463 ? 55.368 63.072 5.097 1.00 11.78 ? 463 ARG A CZ 1 ATOM 3841 N NH1 . ARG A 1 463 ? 55.675 64.069 5.916 1.00 12.53 ? 463 ARG A NH1 1 ATOM 3842 N NH2 . ARG A 1 463 ? 55.770 61.819 5.328 1.00 12.34 ? 463 ARG A NH2 1 ATOM 3843 N N . GLU A 1 464 ? 50.736 67.586 0.021 1.00 6.62 ? 464 GLU A N 1 ATOM 3844 C CA . GLU A 1 464 ? 49.701 68.581 -0.163 1.00 7.46 ? 464 GLU A CA 1 ATOM 3845 C C . GLU A 1 464 ? 48.615 68.032 -1.081 1.00 6.48 ? 464 GLU A C 1 ATOM 3846 O O . GLU A 1 464 ? 47.424 68.238 -0.815 1.00 6.24 ? 464 GLU A O 1 ATOM 3847 C CB . GLU A 1 464 ? 50.235 69.889 -0.741 1.00 8.66 ? 464 GLU A CB 1 ATOM 3848 C CG . GLU A 1 464 ? 51.380 70.562 0.044 1.00 11.66 ? 464 GLU A CG 1 ATOM 3849 C CD . GLU A 1 464 ? 51.076 71.029 1.467 1.00 16.74 ? 464 GLU A CD 1 ATOM 3850 O OE1 . GLU A 1 464 ? 50.047 70.670 2.058 1.00 17.52 ? 464 GLU A OE1 1 ATOM 3851 O OE2 . GLU A 1 464 ? 51.921 71.796 2.005 1.00 20.20 ? 464 GLU A OE2 1 ATOM 3852 N N . LEU A 1 465 ? 49.002 67.330 -2.143 1.00 5.75 ? 465 LEU A N 1 ATOM 3853 C CA . LEU A 1 465 ? 47.992 66.733 -3.025 1.00 6.23 ? 465 LEU A CA 1 ATOM 3854 C C . LEU A 1 465 ? 47.208 65.676 -2.243 1.00 5.06 ? 465 LEU A C 1 ATOM 3855 O O . LEU A 1 465 ? 45.964 65.571 -2.395 1.00 5.73 ? 465 LEU A O 1 ATOM 3856 C CB . LEU A 1 465 ? 48.637 66.092 -4.261 1.00 7.07 ? 465 LEU A CB 1 ATOM 3857 C CG . LEU A 1 465 ? 47.668 65.440 -5.255 1.00 6.35 ? 465 LEU A CG 1 ATOM 3858 C CD1 . LEU A 1 465 ? 46.562 66.384 -5.771 1.00 8.38 ? 465 LEU A CD1 1 ATOM 3859 C CD2 . LEU A 1 465 ? 48.469 64.889 -6.441 1.00 7.78 ? 465 LEU A CD2 1 ATOM 3860 N N . SER A 1 466 ? 47.905 64.893 -1.425 1.00 4.78 ? 466 SER A N 1 ATOM 3861 C CA . SER A 1 466 ? 47.220 63.886 -0.650 1.00 3.92 ? 466 SER A CA 1 ATOM 3862 C C . SER A 1 466 ? 46.223 64.489 0.322 1.00 4.98 ? 466 SER A C 1 ATOM 3863 O O . SER A 1 466 ? 45.109 63.981 0.485 1.00 5.07 ? 466 SER A O 1 ATOM 3864 C CB . SER A 1 466 ? 48.223 63.042 0.134 1.00 4.84 ? 466 SER A CB 1 ATOM 3865 O OG . SER A 1 466 ? 49.022 62.248 -0.716 1.00 6.02 ? 466 SER A OG 1 ATOM 3866 N N . LEU A 1 467 ? 46.614 65.571 0.974 1.00 4.41 ? 467 LEU A N 1 ATOM 3867 C CA . LEU A 1 467 ? 45.737 66.231 1.906 1.00 4.81 ? 467 LEU A CA 1 ATOM 3868 C C . LEU A 1 467 ? 44.420 66.631 1.215 1.00 4.65 ? 467 LEU A C 1 ATOM 3869 O O . LEU A 1 467 ? 43.332 66.522 1.780 1.00 4.93 ? 467 LEU A O 1 ATOM 3870 C CB . LEU A 1 467 ? 46.424 67.466 2.517 1.00 5.44 ? 467 LEU A CB 1 ATOM 3871 C CG . LEU A 1 467 ? 45.577 68.156 3.564 1.00 8.54 ? 467 LEU A CG 1 ATOM 3872 C CD1 . LEU A 1 467 ? 45.548 67.330 4.827 1.00 14.60 ? 467 LEU A CD1 1 ATOM 3873 C CD2 . LEU A 1 467 ? 46.188 69.546 3.869 1.00 10.79 ? 467 LEU A CD2 1 ATOM 3874 N N . PHE A 1 468 ? 44.539 67.138 -0.008 1.00 4.21 ? 468 PHE A N 1 ATOM 3875 C CA . PHE A 1 468 ? 43.341 67.662 -0.697 1.00 4.71 ? 468 PHE A CA 1 ATOM 3876 C C . PHE A 1 468 ? 42.405 66.557 -1.109 1.00 3.89 ? 468 PHE A C 1 ATOM 3877 O O . PHE A 1 468 ? 41.240 66.838 -1.440 1.00 4.86 ? 468 PHE A O 1 ATOM 3878 C CB . PHE A 1 468 ? 43.779 68.502 -1.894 1.00 4.84 ? 468 PHE A CB 1 ATOM 3879 C CG . PHE A 1 468 ? 42.677 69.335 -2.468 1.00 4.73 ? 468 PHE A CG 1 ATOM 3880 C CD1 . PHE A 1 468 ? 42.047 70.296 -1.700 1.00 6.76 ? 468 PHE A CD1 1 ATOM 3881 C CD2 . PHE A 1 468 ? 42.245 69.147 -3.787 1.00 4.89 ? 468 PHE A CD2 1 ATOM 3882 C CE1 . PHE A 1 468 ? 40.997 71.067 -2.216 1.00 6.72 ? 468 PHE A CE1 1 ATOM 3883 C CE2 . PHE A 1 468 ? 41.166 69.932 -4.289 1.00 4.00 ? 468 PHE A CE2 1 ATOM 3884 C CZ . PHE A 1 468 ? 40.559 70.867 -3.489 1.00 5.64 ? 468 PHE A CZ 1 ATOM 3885 N N . GLN A 1 469 ? 42.834 65.294 -1.053 1.00 4.11 ? 469 GLN A N 1 ATOM 3886 C CA . GLN A 1 469 ? 41.890 64.223 -1.356 1.00 3.97 ? 469 GLN A CA 1 ATOM 3887 C C . GLN A 1 469 ? 40.887 64.011 -0.224 1.00 4.89 ? 469 GLN A C 1 ATOM 3888 O O . GLN A 1 469 ? 39.932 63.237 -0.370 1.00 5.03 ? 469 GLN A O 1 ATOM 3889 C CB . GLN A 1 469 ? 42.623 62.895 -1.583 1.00 4.44 ? 469 GLN A CB 1 ATOM 3890 C CG . GLN A 1 469 ? 43.724 62.971 -2.682 1.00 5.27 ? 469 GLN A CG 1 ATOM 3891 C CD . GLN A 1 469 ? 43.212 63.622 -3.933 1.00 6.08 ? 469 GLN A CD 1 ATOM 3892 O OE1 . GLN A 1 469 ? 42.224 63.174 -4.491 1.00 6.65 ? 469 GLN A OE1 1 ATOM 3893 N NE2 . GLN A 1 469 ? 43.847 64.702 -4.350 1.00 5.76 ? 469 GLN A NE2 1 ATOM 3894 N N . HIS A 1 470 ? 41.104 64.668 0.911 1.00 4.12 ? 470 HIS A N 1 ATOM 3895 C CA . HIS A 1 470 ? 40.168 64.595 2.022 1.00 3.65 ? 470 HIS A CA 1 ATOM 3896 C C . HIS A 1 470 ? 38.749 64.848 1.541 1.00 4.75 ? 470 HIS A C 1 ATOM 3897 O O . HIS A 1 470 ? 38.522 65.620 0.603 1.00 5.19 ? 470 HIS A O 1 ATOM 3898 C CB . HIS A 1 470 ? 40.588 65.640 3.073 1.00 5.31 ? 470 HIS A CB 1 ATOM 3899 C CG . HIS A 1 470 ? 39.574 65.905 4.141 1.00 5.30 ? 470 HIS A CG 1 ATOM 3900 N ND1 . HIS A 1 470 ? 38.950 64.892 4.849 1.00 7.70 ? 470 HIS A ND1 1 ATOM 3901 C CD2 . HIS A 1 470 ? 39.088 67.074 4.626 1.00 6.69 ? 470 HIS A CD2 1 ATOM 3902 C CE1 . HIS A 1 470 ? 38.128 65.440 5.733 1.00 6.86 ? 470 HIS A CE1 1 ATOM 3903 N NE2 . HIS A 1 470 ? 38.186 66.756 5.609 1.00 7.95 ? 470 HIS A NE2 1 ATOM 3904 N N . HIS A 1 471 ? 37.785 64.219 2.212 1.00 4.88 ? 471 HIS A N 1 ATOM 3905 C CA . HIS A 1 471 ? 36.375 64.377 1.856 1.00 4.91 ? 471 HIS A CA 1 ATOM 3906 C C . HIS A 1 471 ? 35.760 65.740 2.195 1.00 5.47 ? 471 HIS A C 1 ATOM 3907 O O . HIS A 1 471 ? 34.556 65.908 1.948 1.00 7.18 ? 471 HIS A O 1 ATOM 3908 C CB . HIS A 1 471 ? 35.549 63.216 2.451 1.00 5.85 ? 471 HIS A CB 1 ATOM 3909 C CG . HIS A 1 471 ? 35.630 63.131 3.938 1.00 5.38 ? 471 HIS A CG 1 ATOM 3910 N ND1 . HIS A 1 471 ? 36.595 62.402 4.597 1.00 6.51 ? 471 HIS A ND1 1 ATOM 3911 C CD2 . HIS A 1 471 ? 34.879 63.725 4.894 1.00 8.02 ? 471 HIS A CD2 1 ATOM 3912 C CE1 . HIS A 1 471 ? 36.422 62.550 5.905 1.00 5.84 ? 471 HIS A CE1 1 ATOM 3913 N NE2 . HIS A 1 471 ? 35.399 63.345 6.108 1.00 5.34 ? 471 HIS A NE2 1 ATOM 3914 N N . ASP A 1 472 ? 36.545 66.716 2.657 1.00 6.29 ? 472 ASP A N 1 ATOM 3915 C CA . ASP A 1 472 ? 36.123 68.128 2.601 1.00 7.44 ? 472 ASP A CA 1 ATOM 3916 C C . ASP A 1 472 ? 37.064 69.009 1.819 1.00 7.64 ? 472 ASP A C 1 ATOM 3917 O O . ASP A 1 472 ? 36.932 70.240 1.860 1.00 8.68 ? 472 ASP A O 1 ATOM 3918 C CB . ASP A 1 472 ? 35.943 68.768 3.992 1.00 7.03 ? 472 ASP A CB 1 ATOM 3919 C CG . ASP A 1 472 ? 34.936 68.042 4.837 1.00 8.91 ? 472 ASP A CG 1 ATOM 3920 O OD1 . ASP A 1 472 ? 33.748 68.042 4.432 1.00 9.17 ? 472 ASP A OD1 1 ATOM 3921 O OD2 . ASP A 1 472 ? 35.249 67.441 5.885 1.00 8.86 ? 472 ASP A OD2 1 ATOM 3922 N N . GLY A 1 473 ? 38.018 68.408 1.103 1.00 5.98 ? 473 GLY A N 1 ATOM 3923 C CA . GLY A 1 473 ? 38.983 69.153 0.300 1.00 5.03 ? 473 GLY A CA 1 ATOM 3924 C C . GLY A 1 473 ? 38.429 69.217 -1.107 1.00 4.99 ? 473 GLY A C 1 ATOM 3925 O O . GLY A 1 473 ? 37.707 70.151 -1.465 1.00 5.55 ? 473 GLY A O 1 ATOM 3926 N N . ILE A 1 474 ? 38.750 68.198 -1.886 1.00 4.16 ? 474 ILE A N 1 ATOM 3927 C CA . ILE A 1 474 ? 38.338 68.182 -3.293 1.00 4.97 ? 474 ILE A CA 1 ATOM 3928 C C . ILE A 1 474 ? 36.814 68.306 -3.462 1.00 5.48 ? 474 ILE A C 1 ATOM 3929 O O . ILE A 1 474 ? 36.350 68.841 -4.490 1.00 6.03 ? 474 ILE A O 1 ATOM 3930 C CB . ILE A 1 474 ? 38.909 66.948 -4.000 1.00 5.15 ? 474 ILE A CB 1 ATOM 3931 C CG1 . ILE A 1 474 ? 38.679 67.032 -5.518 1.00 5.57 ? 474 ILE A CG1 1 ATOM 3932 C CG2 . ILE A 1 474 ? 38.397 65.661 -3.339 1.00 5.71 ? 474 ILE A CG2 1 ATOM 3933 C CD1 . ILE A 1 474 ? 39.423 65.948 -6.298 1.00 6.65 ? 474 ILE A CD1 1 ATOM 3934 N N . THR A 1 475 ? 36.060 67.872 -2.453 1.00 3.73 ? 475 THR A N 1 ATOM 3935 C CA . THR A 1 475 ? 34.615 67.961 -2.495 1.00 4.75 ? 475 THR A CA 1 ATOM 3936 C C . THR A 1 475 ? 34.085 69.389 -2.488 1.00 4.87 ? 475 THR A C 1 ATOM 3937 O O . THR A 1 475 ? 32.924 69.599 -2.851 1.00 6.26 ? 475 THR A O 1 ATOM 3938 C CB . THR A 1 475 ? 34.031 67.287 -1.267 1.00 5.86 ? 475 THR A CB 1 ATOM 3939 O OG1 . THR A 1 475 ? 34.554 67.939 -0.104 1.00 6.14 ? 475 THR A OG1 1 ATOM 3940 C CG2 . THR A 1 475 ? 34.435 65.831 -1.166 1.00 6.25 ? 475 THR A CG2 1 ATOM 3941 N N . GLY A 1 476 ? 34.877 70.362 -2.056 1.00 5.05 ? 476 GLY A N 1 ATOM 3942 C CA . GLY A 1 476 ? 34.384 71.722 -2.067 1.00 6.22 ? 476 GLY A CA 1 ATOM 3943 C C . GLY A 1 476 ? 33.421 72.018 -0.949 1.00 6.28 ? 476 GLY A C 1 ATOM 3944 O O . GLY A 1 476 ? 32.525 72.867 -1.107 1.00 6.32 ? 476 GLY A O 1 ATOM 3945 N N . THR A 1 477 ? 33.540 71.284 0.156 1.00 5.44 ? 477 THR A N 1 ATOM 3946 C CA . THR A 1 477 ? 32.617 71.438 1.255 1.00 5.83 ? 477 THR A CA 1 ATOM 3947 C C . THR A 1 477 ? 33.259 72.042 2.505 1.00 6.06 ? 477 THR A C 1 ATOM 3948 O O . THR A 1 477 ? 32.723 71.854 3.607 1.00 7.46 ? 477 THR A O 1 ATOM 3949 C CB . THR A 1 477 ? 31.962 70.091 1.625 1.00 6.99 ? 477 THR A CB 1 ATOM 3950 O OG1 . THR A 1 477 ? 32.982 69.092 1.860 1.00 6.48 ? 477 THR A OG1 1 ATOM 3951 C CG2 . THR A 1 477 ? 31.123 69.549 0.453 1.00 6.57 ? 477 THR A CG2 1 ATOM 3952 N N . ALA A 1 478 ? 34.364 72.779 2.372 1.00 5.10 ? 478 ALA A N 1 ATOM 3953 C CA . ALA A 1 478 ? 34.996 73.410 3.540 1.00 5.92 ? 478 ALA A CA 1 ATOM 3954 C C . ALA A 1 478 ? 34.689 74.889 3.617 1.00 5.46 ? 478 ALA A C 1 ATOM 3955 O O . ALA A 1 478 ? 34.220 75.515 2.646 1.00 6.25 ? 478 ALA A O 1 ATOM 3956 C CB . ALA A 1 478 ? 36.520 73.191 3.485 1.00 6.39 ? 478 ALA A CB 1 ATOM 3957 N N . LYS A 1 479 ? 34.926 75.476 4.786 1.00 5.68 ? 479 LYS A N 1 ATOM 3958 C CA . LYS A 1 479 ? 34.742 76.936 4.896 1.00 7.17 ? 479 LYS A CA 1 ATOM 3959 C C . LYS A 1 479 ? 35.695 77.668 3.962 1.00 7.39 ? 479 LYS A C 1 ATOM 3960 O O . LYS A 1 479 ? 36.764 77.183 3.608 1.00 6.42 ? 479 LYS A O 1 ATOM 3961 C CB . LYS A 1 479 ? 34.926 77.403 6.349 1.00 7.86 ? 479 LYS A CB 1 ATOM 3962 C CG . LYS A 1 479 ? 33.705 77.064 7.210 1.00 10.36 ? 479 LYS A CG 1 ATOM 3963 C CD . LYS A 1 479 ? 33.781 77.808 8.542 1.00 12.50 ? 479 LYS A CD 1 ATOM 3964 C CE . LYS A 1 479 ? 32.510 77.692 9.381 1.00 15.29 ? 479 LYS A CE 1 ATOM 3965 N NZ . LYS A 1 479 ? 31.315 78.303 8.727 1.00 15.33 ? 479 LYS A NZ 1 ATOM 3966 N N . THR A 1 480 ? 35.301 78.886 3.618 1.00 8.36 ? 480 THR A N 1 ATOM 3967 C CA . THR A 1 480 ? 36.110 79.703 2.717 1.00 8.99 ? 480 THR A CA 1 ATOM 3968 C C . THR A 1 480 ? 37.575 79.789 3.116 1.00 8.71 ? 480 THR A C 1 ATOM 3969 O O . THR A 1 480 ? 38.451 79.592 2.271 1.00 8.87 ? 480 THR A O 1 ATOM 3970 C CB . THR A 1 480 ? 35.535 81.123 2.640 1.00 9.91 ? 480 THR A CB 1 ATOM 3971 O OG1 . THR A 1 480 ? 34.240 81.041 2.059 1.00 12.88 ? 480 THR A OG1 1 ATOM 3972 C CG2 . THR A 1 480 ? 36.323 82.038 1.682 1.00 12.66 ? 480 THR A CG2 1 ATOM 3973 N N . HIS A 1 481 ? 37.864 80.060 4.393 1.00 7.99 ? 481 HIS A N 1 ATOM 3974 C CA . HIS A 1 481 ? 39.271 80.208 4.733 1.00 8.22 ? 481 HIS A CA 1 ATOM 3975 C C . HIS A 1 481 ? 40.036 78.907 4.687 1.00 8.05 ? 481 HIS A C 1 ATOM 3976 O O . HIS A 1 481 ? 41.261 78.900 4.552 1.00 7.77 ? 481 HIS A O 1 ATOM 3977 C CB . HIS A 1 481 ? 39.438 80.901 6.103 1.00 9.85 ? 481 HIS A CB 1 ATOM 3978 C CG . HIS A 1 481 ? 39.283 79.994 7.286 1.00 8.90 ? 481 HIS A CG 1 ATOM 3979 N ND1 . HIS A 1 481 ? 38.054 79.562 7.740 1.00 11.49 ? 481 HIS A ND1 1 ATOM 3980 C CD2 . HIS A 1 481 ? 40.205 79.492 8.145 1.00 9.88 ? 481 HIS A CD2 1 ATOM 3981 C CE1 . HIS A 1 481 ? 38.234 78.792 8.804 1.00 11.81 ? 481 HIS A CE1 1 ATOM 3982 N NE2 . HIS A 1 481 ? 39.529 78.748 9.075 1.00 11.26 ? 481 HIS A NE2 1 ATOM 3983 N N . VAL A 1 482 ? 39.301 77.799 4.779 1.00 6.92 ? 482 VAL A N 1 ATOM 3984 C CA . VAL A 1 482 ? 39.947 76.490 4.683 1.00 7.03 ? 482 VAL A CA 1 ATOM 3985 C C . VAL A 1 482 ? 40.244 76.166 3.210 1.00 6.85 ? 482 VAL A C 1 ATOM 3986 O O . VAL A 1 482 ? 41.308 75.646 2.879 1.00 6.45 ? 482 VAL A O 1 ATOM 3987 C CB . VAL A 1 482 ? 39.046 75.409 5.338 1.00 5.49 ? 482 VAL A CB 1 ATOM 3988 C CG1 . VAL A 1 482 ? 39.685 74.012 5.250 1.00 6.94 ? 482 VAL A CG1 1 ATOM 3989 C CG2 . VAL A 1 482 ? 38.767 75.723 6.804 1.00 7.06 ? 482 VAL A CG2 1 ATOM 3990 N N . VAL A 1 483 ? 39.312 76.537 2.340 1.00 6.46 ? 483 VAL A N 1 ATOM 3991 C CA . VAL A 1 483 ? 39.572 76.421 0.914 1.00 6.69 ? 483 VAL A CA 1 ATOM 3992 C C . VAL A 1 483 ? 40.809 77.229 0.496 1.00 6.77 ? 483 VAL A C 1 ATOM 3993 O O . VAL A 1 483 ? 41.652 76.743 -0.264 1.00 6.84 ? 483 VAL A O 1 ATOM 3994 C CB . VAL A 1 483 ? 38.355 76.882 0.086 1.00 6.48 ? 483 VAL A CB 1 ATOM 3995 C CG1 . VAL A 1 483 ? 38.646 76.863 -1.406 1.00 9.18 ? 483 VAL A CG1 1 ATOM 3996 C CG2 . VAL A 1 483 ? 37.114 76.008 0.389 1.00 8.68 ? 483 VAL A CG2 1 ATOM 3997 N N . VAL A 1 484 ? 40.944 78.429 1.066 1.00 8.29 ? 484 VAL A N 1 ATOM 3998 C CA . VAL A 1 484 ? 42.132 79.245 0.814 1.00 8.81 ? 484 VAL A CA 1 ATOM 3999 C C . VAL A 1 484 ? 43.392 78.523 1.273 1.00 8.07 ? 484 VAL A C 1 ATOM 4000 O O . VAL A 1 484 ? 44.392 78.523 0.533 1.00 9.24 ? 484 VAL A O 1 ATOM 4001 C CB . VAL A 1 484 ? 41.996 80.624 1.477 1.00 9.38 ? 484 VAL A CB 1 ATOM 4002 C CG1 . VAL A 1 484 ? 43.335 81.386 1.404 1.00 11.42 ? 484 VAL A CG1 1 ATOM 4003 C CG2 . VAL A 1 484 ? 40.888 81.406 0.785 1.00 10.99 ? 484 VAL A CG2 1 ATOM 4004 N N . ASP A 1 485 ? 43.359 77.874 2.430 1.00 7.07 ? 485 ASP A N 1 ATOM 4005 C CA . ASP A 1 485 ? 44.501 77.108 2.897 1.00 6.61 ? 485 ASP A CA 1 ATOM 4006 C C . ASP A 1 485 ? 44.861 75.983 1.965 1.00 6.71 ? 485 ASP A C 1 ATOM 4007 O O . ASP A 1 485 ? 46.041 75.786 1.653 1.00 7.18 ? 485 ASP A O 1 ATOM 4008 C CB . ASP A 1 485 ? 44.240 76.575 4.307 1.00 7.89 ? 485 ASP A CB 1 ATOM 4009 C CG . ASP A 1 485 ? 45.457 75.954 4.913 1.00 10.05 ? 485 ASP A CG 1 ATOM 4010 O OD1 . ASP A 1 485 ? 46.453 76.712 5.090 1.00 13.28 ? 485 ASP A OD1 1 ATOM 4011 O OD2 . ASP A 1 485 ? 45.502 74.776 5.279 1.00 9.56 ? 485 ASP A OD2 1 ATOM 4012 N N . TYR A 1 486 ? 43.863 75.245 1.496 1.00 5.87 ? 486 TYR A N 1 ATOM 4013 C CA . TYR A 1 486 ? 44.173 74.176 0.542 1.00 6.18 ? 486 TYR A CA 1 ATOM 4014 C C . TYR A 1 486 ? 44.756 74.716 -0.742 1.00 6.48 ? 486 TYR A C 1 ATOM 4015 O O . TYR A 1 486 ? 45.653 74.111 -1.290 1.00 7.19 ? 486 TYR A O 1 ATOM 4016 C CB . TYR A 1 486 ? 42.913 73.384 0.219 1.00 6.93 ? 486 TYR A CB 1 ATOM 4017 C CG . TYR A 1 486 ? 42.331 72.509 1.331 1.00 5.57 ? 486 TYR A CG 1 ATOM 4018 C CD1 . TYR A 1 486 ? 43.126 71.641 2.108 1.00 8.69 ? 486 TYR A CD1 1 ATOM 4019 C CD2 . TYR A 1 486 ? 40.951 72.499 1.533 1.00 7.16 ? 486 TYR A CD2 1 ATOM 4020 C CE1 . TYR A 1 486 ? 42.530 70.800 3.091 1.00 10.20 ? 486 TYR A CE1 1 ATOM 4021 C CE2 . TYR A 1 486 ? 40.369 71.671 2.499 1.00 6.79 ? 486 TYR A CE2 1 ATOM 4022 C CZ . TYR A 1 486 ? 41.158 70.831 3.249 1.00 7.43 ? 486 TYR A CZ 1 ATOM 4023 O OH . TYR A 1 486 ? 40.576 70.004 4.198 1.00 10.40 ? 486 TYR A OH 1 ATOM 4024 N N . GLU A 1 487 ? 44.236 75.836 -1.219 1.00 7.24 ? 487 GLU A N 1 ATOM 4025 C CA . GLU A 1 487 ? 44.731 76.412 -2.452 1.00 7.45 ? 487 GLU A CA 1 ATOM 4026 C C . GLU A 1 487 ? 46.198 76.844 -2.289 1.00 8.09 ? 487 GLU A C 1 ATOM 4027 O O . GLU A 1 487 ? 47.032 76.600 -3.187 1.00 8.92 ? 487 GLU A O 1 ATOM 4028 C CB . GLU A 1 487 ? 43.905 77.621 -2.842 1.00 7.28 ? 487 GLU A CB 1 ATOM 4029 C CG . GLU A 1 487 ? 44.306 78.181 -4.197 1.00 11.21 ? 487 GLU A CG 1 ATOM 4030 C CD . GLU A 1 487 ? 43.407 79.303 -4.658 1.00 16.31 ? 487 GLU A CD 1 ATOM 4031 O OE1 . GLU A 1 487 ? 42.267 79.451 -4.152 1.00 17.38 ? 487 GLU A OE1 1 ATOM 4032 O OE2 . GLU A 1 487 ? 43.862 80.039 -5.577 1.00 20.65 ? 487 GLU A OE2 1 ATOM 4033 N N . GLN A 1 488 ? 46.507 77.501 -1.173 1.00 7.85 ? 488 GLN A N 1 ATOM 4034 C CA . GLN A 1 488 ? 47.880 77.950 -0.930 1.00 8.50 ? 488 GLN A CA 1 ATOM 4035 C C . GLN A 1 488 ? 48.796 76.746 -0.833 1.00 7.98 ? 488 GLN A C 1 ATOM 4036 O O . GLN A 1 488 ? 49.922 76.783 -1.355 1.00 8.48 ? 488 GLN A O 1 ATOM 4037 C CB . GLN A 1 488 ? 47.960 78.727 0.394 1.00 10.88 ? 488 GLN A CB 1 ATOM 4038 C CG . GLN A 1 488 ? 47.188 80.023 0.372 1.00 15.76 ? 488 GLN A CG 1 ATOM 4039 C CD . GLN A 1 488 ? 47.232 80.719 1.728 1.00 21.00 ? 488 GLN A CD 1 ATOM 4040 O OE1 . GLN A 1 488 ? 47.325 80.070 2.782 1.00 25.00 ? 488 GLN A OE1 1 ATOM 4041 N NE2 . GLN A 1 488 ? 47.158 82.026 1.705 1.00 25.36 ? 488 GLN A NE2 1 ATOM 4042 N N . ARG A 1 489 ? 48.362 75.671 -0.172 1.00 7.02 ? 489 ARG A N 1 ATOM 4043 C CA . ARG A 1 489 ? 49.178 74.473 -0.091 1.00 7.79 ? 489 ARG A CA 1 ATOM 4044 C C . ARG A 1 489 ? 49.386 73.885 -1.480 1.00 7.56 ? 489 ARG A C 1 ATOM 4045 O O . ARG A 1 489 ? 50.504 73.489 -1.813 1.00 7.19 ? 489 ARG A O 1 ATOM 4046 C CB . ARG A 1 489 ? 48.520 73.455 0.818 1.00 8.02 ? 489 ARG A CB 1 ATOM 4047 C CG . ARG A 1 489 ? 48.539 73.819 2.282 1.00 6.95 ? 489 ARG A CG 1 ATOM 4048 C CD . ARG A 1 489 ? 47.582 72.875 3.058 1.00 9.50 ? 489 ARG A CD 1 ATOM 4049 N NE . ARG A 1 489 ? 47.687 73.026 4.508 1.00 8.60 ? 489 ARG A NE 1 ATOM 4050 C CZ . ARG A 1 489 ? 48.563 72.374 5.294 1.00 11.06 ? 489 ARG A CZ 1 ATOM 4051 N NH1 . ARG A 1 489 ? 49.456 71.531 4.798 1.00 12.23 ? 489 ARG A NH1 1 ATOM 4052 N NH2 . ARG A 1 489 ? 48.543 72.594 6.607 1.00 11.35 ? 489 ARG A NH2 1 ATOM 4053 N N . MET A 1 490 ? 48.345 73.836 -2.307 1.00 6.87 ? 490 MET A N 1 ATOM 4054 C CA . MET A 1 490 ? 48.538 73.285 -3.646 1.00 7.82 ? 490 MET A CA 1 ATOM 4055 C C . MET A 1 490 ? 49.413 74.176 -4.510 1.00 7.64 ? 490 MET A C 1 ATOM 4056 O O . MET A 1 490 ? 50.170 73.657 -5.338 1.00 6.93 ? 490 MET A O 1 ATOM 4057 C CB . MET A 1 490 ? 47.202 73.026 -4.343 1.00 8.26 ? 490 MET A CB 1 ATOM 4058 C CG . MET A 1 490 ? 46.467 71.832 -3.686 1.00 9.07 ? 490 MET A CG 1 ATOM 4059 S SD . MET A 1 490 ? 45.169 71.123 -4.802 1.00 12.55 ? 490 MET A SD 1 ATOM 4060 C CE . MET A 1 490 ? 43.894 72.311 -4.547 1.00 14.39 ? 490 MET A CE 1 ATOM 4061 N N . GLN A 1 491 ? 49.328 75.492 -4.329 1.00 7.07 ? 491 GLN A N 1 ATOM 4062 C CA . GLN A 1 491 ? 50.234 76.358 -5.082 1.00 7.38 ? 491 GLN A CA 1 ATOM 4063 C C . GLN A 1 491 ? 51.692 76.112 -4.728 1.00 7.98 ? 491 GLN A C 1 ATOM 4064 O O . GLN A 1 491 ? 52.553 76.094 -5.607 1.00 8.57 ? 491 GLN A O 1 ATOM 4065 C CB . GLN A 1 491 ? 49.875 77.823 -4.826 1.00 8.88 ? 491 GLN A CB 1 ATOM 4066 C CG . GLN A 1 491 ? 50.617 78.795 -5.733 1.00 14.19 ? 491 GLN A CG 1 ATOM 4067 C CD . GLN A 1 491 ? 50.484 78.441 -7.190 1.00 22.31 ? 491 GLN A CD 1 ATOM 4068 O OE1 . GLN A 1 491 ? 51.484 78.245 -7.883 1.00 27.45 ? 491 GLN A OE1 1 ATOM 4069 N NE2 . GLN A 1 491 ? 49.258 78.324 -7.650 1.00 25.86 ? 491 GLN A NE2 1 ATOM 4070 N N . GLU A 1 492 ? 51.966 75.951 -3.438 1.00 7.63 ? 492 GLU A N 1 ATOM 4071 C CA . GLU A 1 492 ? 53.313 75.612 -3.019 1.00 8.65 ? 492 GLU A CA 1 ATOM 4072 C C . GLU A 1 492 ? 53.735 74.293 -3.621 1.00 8.43 ? 492 GLU A C 1 ATOM 4073 O O . GLU A 1 492 ? 54.883 74.135 -4.055 1.00 9.06 ? 492 GLU A O 1 ATOM 4074 C CB . GLU A 1 492 ? 53.429 75.590 -1.488 1.00 9.79 ? 492 GLU A CB 1 ATOM 4075 C CG . GLU A 1 492 ? 53.360 76.991 -0.844 1.00 16.60 ? 492 GLU A CG 1 ATOM 4076 C CD . GLU A 1 492 ? 54.257 78.035 -1.518 1.00 25.25 ? 492 GLU A CD 1 ATOM 4077 O OE1 . GLU A 1 492 ? 55.464 77.762 -1.763 1.00 28.53 ? 492 GLU A OE1 1 ATOM 4078 O OE2 . GLU A 1 492 ? 53.773 79.160 -1.801 1.00 29.95 ? 492 GLU A OE2 1 ATOM 4079 N N . ALA A 1 493 ? 52.825 73.330 -3.676 1.00 7.02 ? 493 ALA A N 1 ATOM 4080 C CA . ALA A 1 493 ? 53.143 72.043 -4.262 1.00 6.32 ? 493 ALA A CA 1 ATOM 4081 C C . ALA A 1 493 ? 53.473 72.165 -5.758 1.00 6.64 ? 493 ALA A C 1 ATOM 4082 O O . ALA A 1 493 ? 54.355 71.461 -6.254 1.00 6.06 ? 493 ALA A O 1 ATOM 4083 C CB . ALA A 1 493 ? 51.970 71.070 -4.029 1.00 6.29 ? 493 ALA A CB 1 ATOM 4084 N N . LEU A 1 494 ? 52.712 72.975 -6.492 1.00 6.03 ? 494 LEU A N 1 ATOM 4085 C CA . LEU A 1 494 ? 52.996 73.187 -7.910 1.00 6.93 ? 494 LEU A CA 1 ATOM 4086 C C . LEU A 1 494 ? 54.373 73.782 -8.093 1.00 6.73 ? 494 LEU A C 1 ATOM 4087 O O . LEU A 1 494 ? 55.095 73.391 -8.993 1.00 7.46 ? 494 LEU A O 1 ATOM 4088 C CB . LEU A 1 494 ? 51.955 74.081 -8.553 1.00 7.36 ? 494 LEU A CB 1 ATOM 4089 C CG . LEU A 1 494 ? 50.592 73.431 -8.758 1.00 8.33 ? 494 LEU A CG 1 ATOM 4090 C CD1 . LEU A 1 494 ? 49.574 74.515 -9.102 1.00 9.76 ? 494 LEU A CD1 1 ATOM 4091 C CD2 . LEU A 1 494 ? 50.645 72.393 -9.847 1.00 7.87 ? 494 LEU A CD2 1 ATOM 4092 N N . LYS A 1 495 ? 54.743 74.719 -7.229 1.00 7.24 ? 495 LYS A N 1 ATOM 4093 C CA . LYS A 1 495 ? 56.084 75.340 -7.310 1.00 7.61 ? 495 LYS A CA 1 ATOM 4094 C C . LYS A 1 495 ? 57.166 74.326 -7.024 1.00 7.84 ? 495 LYS A C 1 ATOM 4095 O O . LYS A 1 495 ? 58.204 74.332 -7.704 1.00 8.59 ? 495 LYS A O 1 ATOM 4096 C CB . LYS A 1 495 ? 56.192 76.500 -6.323 1.00 9.66 ? 495 LYS A CB 1 ATOM 4097 C CG . LYS A 1 495 ? 55.354 77.700 -6.713 1.00 12.70 ? 495 LYS A CG 1 ATOM 4098 C CD . LYS A 1 495 ? 55.732 78.901 -5.848 1.00 19.33 ? 495 LYS A CD 1 ATOM 4099 C CE . LYS A 1 495 ? 54.725 79.188 -4.784 1.00 24.29 ? 495 LYS A CE 1 ATOM 4100 N NZ . LYS A 1 495 ? 55.149 80.364 -3.944 1.00 28.15 ? 495 LYS A NZ 1 ATOM 4101 N N . ALA A 1 496 ? 56.906 73.410 -6.085 1.00 6.03 ? 496 ALA A N 1 ATOM 4102 C CA . ALA A 1 496 ? 57.861 72.353 -5.783 1.00 6.51 ? 496 ALA A CA 1 ATOM 4103 C C . ALA A 1 496 ? 58.023 71.425 -6.979 1.00 7.31 ? 496 ALA A C 1 ATOM 4104 O O . ALA A 1 496 ? 59.119 71.007 -7.358 1.00 6.81 ? 496 ALA A O 1 ATOM 4105 C CB . ALA A 1 496 ? 57.374 71.571 -4.544 1.00 6.88 ? 496 ALA A CB 1 ATOM 4106 N N . CYS A 1 497 ? 56.908 71.059 -7.591 1.00 6.19 ? 497 CYS A N 1 ATOM 4107 C CA . CYS A 1 497 ? 56.992 70.191 -8.767 1.00 6.80 ? 497 CYS A CA 1 ATOM 4108 C C . CYS A 1 497 ? 57.750 70.876 -9.887 1.00 6.93 ? 497 CYS A C 1 ATOM 4109 O O . CYS A 1 497 ? 58.564 70.238 -10.542 1.00 7.06 ? 497 CYS A O 1 ATOM 4110 C CB . CYS A 1 497 ? 55.592 69.859 -9.260 1.00 5.53 ? 497 CYS A CB 1 ATOM 4111 S SG . CYS A 1 497 ? 54.678 68.714 -8.241 1.00 8.51 ? 497 CYS A SG 1 ATOM 4112 N N . GLN A 1 498 ? 57.459 72.140 -10.154 1.00 6.52 ? 498 GLN A N 1 ATOM 4113 C CA . GLN A 1 498 ? 58.185 72.856 -11.202 1.00 6.89 ? 498 GLN A CA 1 ATOM 4114 C C . GLN A 1 498 ? 59.681 72.808 -10.934 1.00 7.01 ? 498 GLN A C 1 ATOM 4115 O O . GLN A 1 498 ? 60.475 72.601 -11.867 1.00 6.99 ? 498 GLN A O 1 ATOM 4116 C CB . GLN A 1 498 ? 57.699 74.290 -11.324 1.00 7.55 ? 498 GLN A CB 1 ATOM 4117 C CG . GLN A 1 498 ? 58.562 75.137 -12.283 1.00 11.40 ? 498 GLN A CG 1 ATOM 4118 C CD . GLN A 1 498 ? 58.043 76.543 -12.464 1.00 13.81 ? 498 GLN A CD 1 ATOM 4119 O OE1 . GLN A 1 498 ? 57.785 76.965 -13.589 1.00 14.28 ? 498 GLN A OE1 1 ATOM 4120 N NE2 . GLN A 1 498 ? 57.946 77.299 -11.365 1.00 14.27 ? 498 GLN A NE2 1 ATOM 4121 N N . MET A 1 499 ? 60.083 73.073 -9.705 1.00 6.52 ? 499 MET A N 1 ATOM 4122 C CA . MET A 1 499 ? 61.488 73.082 -9.367 1.00 6.66 ? 499 MET A CA 1 ATOM 4123 C C . MET A 1 499 ? 62.132 71.740 -9.662 1.00 6.81 ? 499 MET A C 1 ATOM 4124 O O . MET A 1 499 ? 63.166 71.688 -10.278 1.00 7.65 ? 499 MET A O 1 ATOM 4125 C CB . MET A 1 499 ? 61.683 73.465 -7.900 1.00 7.93 ? 499 MET A CB 1 ATOM 4126 C CG . MET A 1 499 ? 63.123 73.283 -7.366 1.00 9.88 ? 499 MET A CG 1 ATOM 4127 S SD . MET A 1 499 ? 64.401 74.298 -8.195 1.00 18.05 ? 499 MET A SD 1 ATOM 4128 C CE . MET A 1 499 ? 63.674 75.834 -7.857 1.00 13.37 ? 499 MET A CE 1 ATOM 4129 N N . VAL A 1 500 ? 61.493 70.654 -9.246 1.00 5.96 ? 500 VAL A N 1 ATOM 4130 C CA . VAL A 1 500 ? 62.069 69.350 -9.465 1.00 6.48 ? 500 VAL A CA 1 ATOM 4131 C C . VAL A 1 500 ? 62.104 69.038 -10.953 1.00 6.57 ? 500 VAL A C 1 ATOM 4132 O O . VAL A 1 500 ? 63.096 68.510 -11.450 1.00 6.73 ? 500 VAL A O 1 ATOM 4133 C CB . VAL A 1 500 ? 61.298 68.262 -8.676 1.00 6.37 ? 500 VAL A CB 1 ATOM 4134 C CG1 . VAL A 1 500 ? 61.755 66.891 -9.064 1.00 6.53 ? 500 VAL A CG1 1 ATOM 4135 C CG2 . VAL A 1 500 ? 61.479 68.479 -7.189 1.00 8.01 ? 500 VAL A CG2 1 ATOM 4136 N N . MET A 1 501 ? 61.034 69.351 -11.656 1.00 6.21 ? 501 MET A N 1 ATOM 4137 C CA . MET A 1 501 ? 60.957 69.046 -13.080 1.00 7.21 ? 501 MET A CA 1 ATOM 4138 C C . MET A 1 501 ? 62.041 69.786 -13.838 1.00 6.42 ? 501 MET A C 1 ATOM 4139 O O . MET A 1 501 ? 62.726 69.192 -14.646 1.00 6.58 ? 501 MET A O 1 ATOM 4140 C CB . MET A 1 501 ? 59.598 69.416 -13.652 1.00 6.92 ? 501 MET A CB 1 ATOM 4141 C CG . MET A 1 501 ? 58.479 68.474 -13.178 1.00 7.15 ? 501 MET A CG 1 ATOM 4142 S SD . MET A 1 501 ? 56.797 69.083 -13.489 1.00 11.67 ? 501 MET A SD 1 ATOM 4143 C CE . MET A 1 501 ? 56.703 68.860 -15.256 1.00 13.28 ? 501 MET A CE 1 ATOM 4144 N N . GLN A 1 502 ? 62.210 71.072 -13.567 1.00 6.31 ? 502 GLN A N 1 ATOM 4145 C CA . GLN A 1 502 ? 63.139 71.835 -14.410 1.00 6.98 ? 502 GLN A CA 1 ATOM 4146 C C . GLN A 1 502 ? 64.586 71.467 -14.094 1.00 7.65 ? 502 GLN A C 1 ATOM 4147 O O . GLN A 1 502 ? 65.436 71.422 -15.009 1.00 7.52 ? 502 GLN A O 1 ATOM 4148 C CB . GLN A 1 502 ? 62.860 73.317 -14.290 1.00 8.69 ? 502 GLN A CB 1 ATOM 4149 C CG . GLN A 1 502 ? 63.067 73.945 -12.924 1.00 9.53 ? 502 GLN A CG 1 ATOM 4150 C CD . GLN A 1 502 ? 64.489 74.479 -12.719 1.00 11.34 ? 502 GLN A CD 1 ATOM 4151 O OE1 . GLN A 1 502 ? 65.241 74.605 -13.697 1.00 11.15 ? 502 GLN A OE1 1 ATOM 4152 N NE2 . GLN A 1 502 ? 64.861 74.776 -11.482 1.00 11.82 ? 502 GLN A NE2 1 ATOM 4153 N N . GLN A 1 503 ? 64.885 71.144 -12.835 1.00 6.15 ? 503 GLN A N 1 ATOM 4154 C CA . GLN A 1 503 ? 66.257 70.651 -12.542 1.00 7.29 ? 503 GLN A CA 1 ATOM 4155 C C . GLN A 1 503 ? 66.479 69.337 -13.260 1.00 6.92 ? 503 GLN A C 1 ATOM 4156 O O . GLN A 1 503 ? 67.593 69.063 -13.750 1.00 7.92 ? 503 GLN A O 1 ATOM 4157 C CB . GLN A 1 503 ? 66.503 70.440 -11.047 1.00 8.44 ? 503 GLN A CB 1 ATOM 4158 C CG . GLN A 1 503 ? 66.605 71.722 -10.226 1.00 10.23 ? 503 GLN A CG 1 ATOM 4159 C CD . GLN A 1 503 ? 67.965 72.396 -10.396 1.00 12.56 ? 503 GLN A CD 1 ATOM 4160 O OE1 . GLN A 1 503 ? 68.944 71.733 -10.706 1.00 12.84 ? 503 GLN A OE1 1 ATOM 4161 N NE2 . GLN A 1 503 ? 68.014 73.702 -10.204 1.00 14.32 ? 503 GLN A NE2 1 ATOM 4162 N N . SER A 1 504 ? 65.437 68.501 -13.341 1.00 6.91 ? 504 SER A N 1 ATOM 4163 C CA . SER A 1 504 ? 65.594 67.206 -13.965 1.00 6.77 ? 504 SER A CA 1 ATOM 4164 C C . SER A 1 504 ? 65.796 67.337 -15.480 1.00 7.50 ? 504 SER A C 1 ATOM 4165 O O . SER A 1 504 ? 66.627 66.610 -16.064 1.00 7.83 ? 504 SER A O 1 ATOM 4166 C CB . SER A 1 504 ? 64.355 66.313 -13.706 1.00 7.40 ? 504 SER A CB 1 ATOM 4167 O OG . SER A 1 504 ? 64.217 66.046 -12.314 1.00 8.36 ? 504 SER A OG 1 ATOM 4168 N N . VAL A 1 505 ? 65.025 68.224 -16.116 1.00 7.23 ? 505 VAL A N 1 ATOM 4169 C CA . VAL A 1 505 ? 65.183 68.424 -17.555 1.00 7.55 ? 505 VAL A CA 1 ATOM 4170 C C . VAL A 1 505 ? 66.617 68.916 -17.867 1.00 8.24 ? 505 VAL A C 1 ATOM 4171 O O . VAL A 1 505 ? 67.244 68.432 -18.809 1.00 8.08 ? 505 VAL A O 1 ATOM 4172 C CB . VAL A 1 505 ? 64.138 69.417 -18.077 1.00 8.25 ? 505 VAL A CB 1 ATOM 4173 C CG1 . VAL A 1 505 ? 64.451 69.780 -19.549 1.00 8.76 ? 505 VAL A CG1 1 ATOM 4174 C CG2 . VAL A 1 505 ? 62.744 68.827 -17.973 1.00 8.43 ? 505 VAL A CG2 1 ATOM 4175 N N A TYR A 1 506 ? 67.097 69.857 -17.089 0.50 8.15 ? 506 TYR A N 1 ATOM 4176 N N B TYR A 1 506 ? 67.139 69.852 -17.068 0.50 8.32 ? 506 TYR A N 1 ATOM 4177 C CA A TYR A 1 506 ? 68.424 70.350 -17.333 0.50 8.71 ? 506 TYR A CA 1 ATOM 4178 C CA B TYR A 1 506 ? 68.511 70.371 -17.270 0.50 8.90 ? 506 TYR A CA 1 ATOM 4179 C C A TYR A 1 506 ? 69.418 69.171 -17.279 0.50 8.45 ? 506 TYR A C 1 ATOM 4180 C C B TYR A 1 506 ? 69.576 69.295 -17.111 0.50 8.69 ? 506 TYR A C 1 ATOM 4181 O O A TYR A 1 506 ? 70.193 68.937 -18.234 0.50 8.10 ? 506 TYR A O 1 ATOM 4182 O O B TYR A 1 506 ? 70.614 69.289 -17.767 0.50 8.64 ? 506 TYR A O 1 ATOM 4183 C CB A TYR A 1 506 ? 68.724 71.483 -16.364 0.50 8.90 ? 506 TYR A CB 1 ATOM 4184 C CB B TYR A 1 506 ? 68.836 71.565 -16.357 0.50 9.48 ? 506 TYR A CB 1 ATOM 4185 C CG A TYR A 1 506 ? 69.939 72.269 -16.735 0.50 9.83 ? 506 TYR A CG 1 ATOM 4186 C CG B TYR A 1 506 ? 70.320 71.970 -16.374 0.50 9.87 ? 506 TYR A CG 1 ATOM 4187 C CD1 A TYR A 1 506 ? 70.049 72.905 -17.985 0.50 8.86 ? 506 TYR A CD1 1 ATOM 4188 C CD1 B TYR A 1 506 ? 70.922 72.427 -17.545 0.50 13.41 ? 506 TYR A CD1 1 ATOM 4189 C CD2 A TYR A 1 506 ? 70.993 72.350 -15.850 0.50 10.08 ? 506 TYR A CD2 1 ATOM 4190 C CD2 B TYR A 1 506 ? 71.105 71.886 -15.226 0.50 11.22 ? 506 TYR A CD2 1 ATOM 4191 C CE1 A TYR A 1 506 ? 71.201 73.611 -18.310 0.50 9.79 ? 506 TYR A CE1 1 ATOM 4192 C CE1 B TYR A 1 506 ? 72.280 72.782 -17.581 0.50 10.37 ? 506 TYR A CE1 1 ATOM 4193 C CE2 A TYR A 1 506 ? 72.144 73.039 -16.176 0.50 8.44 ? 506 TYR A CE2 1 ATOM 4194 C CE2 B TYR A 1 506 ? 72.482 72.242 -15.251 0.50 9.52 ? 506 TYR A CE2 1 ATOM 4195 C CZ A TYR A 1 506 ? 72.237 73.659 -17.392 0.50 9.33 ? 506 TYR A CZ 1 ATOM 4196 C CZ B TYR A 1 506 ? 73.051 72.685 -16.436 0.50 10.51 ? 506 TYR A CZ 1 ATOM 4197 O OH A TYR A 1 506 ? 73.405 74.328 -17.664 0.50 11.29 ? 506 TYR A OH 1 ATOM 4198 O OH B TYR A 1 506 ? 74.396 73.046 -16.499 0.50 10.65 ? 506 TYR A OH 1 ATOM 4199 N N . ARG A 1 507 ? 69.335 68.352 -16.228 1.00 7.85 ? 507 ARG A N 1 ATOM 4200 C CA . ARG A 1 507 ? 70.260 67.227 -16.099 1.00 8.57 ? 507 ARG A CA 1 ATOM 4201 C C . ARG A 1 507 ? 70.127 66.224 -17.260 1.00 8.55 ? 507 ARG A C 1 ATOM 4202 O O . ARG A 1 507 ? 71.115 65.691 -17.762 1.00 10.22 ? 507 ARG A O 1 ATOM 4203 C CB . ARG A 1 507 ? 70.042 66.504 -14.766 1.00 8.21 ? 507 ARG A CB 1 ATOM 4204 C CG . ARG A 1 507 ? 71.138 65.502 -14.402 1.00 10.55 ? 507 ARG A CG 1 ATOM 4205 C CD . ARG A 1 507 ? 71.022 65.071 -12.966 1.00 10.83 ? 507 ARG A CD 1 ATOM 4206 N NE . ARG A 1 507 ? 72.029 64.073 -12.590 1.00 13.08 ? 507 ARG A NE 1 ATOM 4207 C CZ . ARG A 1 507 ? 72.073 63.479 -11.381 1.00 13.29 ? 507 ARG A CZ 1 ATOM 4208 N NH1 . ARG A 1 507 ? 71.202 63.800 -10.432 1.00 14.14 ? 507 ARG A NH1 1 ATOM 4209 N NH2 . ARG A 1 507 ? 72.978 62.534 -11.139 1.00 15.58 ? 507 ARG A NH2 1 ATOM 4210 N N . LEU A 1 508 ? 68.901 65.921 -17.661 1.00 7.95 ? 508 LEU A N 1 ATOM 4211 C CA . LEU A 1 508 ? 68.681 64.886 -18.650 1.00 7.79 ? 508 LEU A CA 1 ATOM 4212 C C . LEU A 1 508 ? 69.114 65.306 -20.055 1.00 8.13 ? 508 LEU A C 1 ATOM 4213 O O . LEU A 1 508 ? 69.352 64.436 -20.920 1.00 9.41 ? 508 LEU A O 1 ATOM 4214 C CB . LEU A 1 508 ? 67.191 64.521 -18.660 1.00 7.85 ? 508 LEU A CB 1 ATOM 4215 C CG . LEU A 1 508 ? 66.731 63.704 -17.444 1.00 7.48 ? 508 LEU A CG 1 ATOM 4216 C CD1 . LEU A 1 508 ? 65.180 63.786 -17.374 1.00 8.55 ? 508 LEU A CD1 1 ATOM 4217 C CD2 . LEU A 1 508 ? 67.203 62.251 -17.591 1.00 9.68 ? 508 LEU A CD2 1 ATOM 4218 N N . LEU A 1 509 ? 69.156 66.623 -20.307 1.00 8.64 ? 509 LEU A N 1 ATOM 4219 C CA . LEU A 1 509 ? 69.428 67.147 -21.645 1.00 8.67 ? 509 LEU A CA 1 ATOM 4220 C C . LEU A 1 509 ? 70.690 67.998 -21.714 1.00 9.87 ? 509 LEU A C 1 ATOM 4221 O O . LEU A 1 509 ? 70.847 68.748 -22.680 1.00 10.62 ? 509 LEU A O 1 ATOM 4222 C CB . LEU A 1 509 ? 68.222 67.959 -22.139 1.00 8.97 ? 509 LEU A CB 1 ATOM 4223 C CG . LEU A 1 509 ? 66.985 67.125 -22.479 1.00 8.64 ? 509 LEU A CG 1 ATOM 4224 C CD1 . LEU A 1 509 ? 65.870 68.056 -22.898 1.00 8.96 ? 509 LEU A CD1 1 ATOM 4225 C CD2 . LEU A 1 509 ? 67.250 66.116 -23.593 1.00 10.19 ? 509 LEU A CD2 1 ATOM 4226 N N . THR A 1 510 ? 71.596 67.851 -20.757 1.00 10.19 ? 510 THR A N 1 ATOM 4227 C CA . THR A 1 510 ? 72.883 68.548 -20.879 1.00 10.57 ? 510 THR A CA 1 ATOM 4228 C C . THR A 1 510 ? 74.013 67.521 -20.897 1.00 11.49 ? 510 THR A C 1 ATOM 4229 O O . THR A 1 510 ? 73.994 66.521 -20.142 1.00 11.64 ? 510 THR A O 1 ATOM 4230 C CB . THR A 1 510 ? 73.061 69.533 -19.720 1.00 10.90 ? 510 THR A CB 1 ATOM 4231 O OG1 . THR A 1 510 ? 71.995 70.497 -19.722 1.00 10.58 ? 510 THR A OG1 1 ATOM 4232 C CG2 . THR A 1 510 ? 74.318 70.410 -19.920 1.00 10.70 ? 510 THR A CG2 1 ATOM 4233 N N . LYS A 1 511 ? 74.986 67.737 -21.787 1.00 12.84 ? 511 LYS A N 1 ATOM 4234 C CA . LYS A 1 511 ? 76.126 66.819 -21.917 1.00 13.45 ? 511 LYS A CA 1 ATOM 4235 C C . LYS A 1 511 ? 76.729 66.624 -20.528 1.00 13.35 ? 511 LYS A C 1 ATOM 4236 O O . LYS A 1 511 ? 76.985 67.598 -19.843 1.00 12.11 ? 511 LYS A O 1 ATOM 4237 C CB . LYS A 1 511 ? 77.150 67.446 -22.854 1.00 14.95 ? 511 LYS A CB 1 ATOM 4238 C CG . LYS A 1 511 ? 78.410 66.606 -23.084 1.00 18.53 ? 511 LYS A CG 1 ATOM 4239 C CD . LYS A 1 511 ? 79.219 67.232 -24.201 1.00 21.61 ? 511 LYS A CD 1 ATOM 4240 C CE . LYS A 1 511 ? 80.479 66.462 -24.478 1.00 25.24 ? 511 LYS A CE 1 ATOM 4241 N NZ . LYS A 1 511 ? 81.203 67.101 -25.612 1.00 29.55 ? 511 LYS A NZ 1 ATOM 4242 N N . PRO A 1 512 ? 76.905 65.387 -20.063 1.00 14.69 ? 512 PRO A N 1 ATOM 4243 C CA . PRO A 1 512 ? 77.302 65.166 -18.666 1.00 15.70 ? 512 PRO A CA 1 ATOM 4244 C C . PRO A 1 512 ? 78.587 65.864 -18.221 1.00 15.23 ? 512 PRO A C 1 ATOM 4245 O O . PRO A 1 512 ? 78.655 66.315 -17.077 1.00 15.42 ? 512 PRO A O 1 ATOM 4246 C CB . PRO A 1 512 ? 77.453 63.648 -18.579 1.00 16.29 ? 512 PRO A CB 1 ATOM 4247 C CG . PRO A 1 512 ? 76.541 63.145 -19.634 1.00 16.48 ? 512 PRO A CG 1 ATOM 4248 C CD . PRO A 1 512 ? 76.628 64.119 -20.778 1.00 14.87 ? 512 PRO A CD 1 ATOM 4249 N N . SER A 1 513 ? 79.578 65.995 -19.106 1.00 15.25 ? 513 SER A N 1 ATOM 4250 C CA . SER A 1 513 ? 80.825 66.646 -18.696 1.00 15.24 ? 513 SER A CA 1 ATOM 4251 C C . SER A 1 513 ? 80.733 68.176 -18.679 1.00 15.41 ? 513 SER A C 1 ATOM 4252 O O . SER A 1 513 ? 81.678 68.855 -18.294 1.00 15.34 ? 513 SER A O 1 ATOM 4253 C CB . SER A 1 513 ? 81.969 66.188 -19.595 1.00 15.34 ? 513 SER A CB 1 ATOM 4254 O OG . SER A 1 513 ? 81.689 66.540 -20.922 1.00 15.81 ? 513 SER A OG 1 ATOM 4255 N N . ILE A 1 514 ? 79.582 68.717 -19.081 1.00 14.85 ? 514 ILE A N 1 ATOM 4256 C CA . ILE A 1 514 ? 79.313 70.152 -19.063 1.00 15.33 ? 514 ILE A CA 1 ATOM 4257 C C . ILE A 1 514 ? 78.336 70.495 -17.932 1.00 13.88 ? 514 ILE A C 1 ATOM 4258 O O . ILE A 1 514 ? 78.373 71.584 -17.372 1.00 14.06 ? 514 ILE A O 1 ATOM 4259 C CB . ILE A 1 514 ? 78.728 70.619 -20.428 1.00 15.28 ? 514 ILE A CB 1 ATOM 4260 C CG1 . ILE A 1 514 ? 79.789 70.465 -21.528 1.00 18.13 ? 514 ILE A CG1 1 ATOM 4261 C CG2 . ILE A 1 514 ? 78.194 72.079 -20.331 1.00 15.92 ? 514 ILE A CG2 1 ATOM 4262 C CD1 . ILE A 1 514 ? 79.266 70.634 -22.938 1.00 19.25 ? 514 ILE A CD1 1 ATOM 4263 N N . TYR A 1 515 ? 77.487 69.541 -17.581 1.00 12.66 ? 515 TYR A N 1 ATOM 4264 C CA . TYR A 1 515 ? 76.430 69.780 -16.586 1.00 11.87 ? 515 TYR A CA 1 ATOM 4265 C C . TYR A 1 515 ? 77.002 70.333 -15.290 1.00 11.83 ? 515 TYR A C 1 ATOM 4266 O O . TYR A 1 515 ? 77.869 69.712 -14.663 1.00 11.64 ? 515 TYR A O 1 ATOM 4267 C CB . TYR A 1 515 ? 75.734 68.452 -16.360 1.00 11.11 ? 515 TYR A CB 1 ATOM 4268 C CG . TYR A 1 515 ? 74.713 68.432 -15.263 1.00 11.79 ? 515 TYR A CG 1 ATOM 4269 C CD1 . TYR A 1 515 ? 73.558 69.178 -15.339 1.00 9.58 ? 515 TYR A CD1 1 ATOM 4270 C CD2 . TYR A 1 515 ? 74.918 67.645 -14.155 1.00 11.14 ? 515 TYR A CD2 1 ATOM 4271 C CE1 . TYR A 1 515 ? 72.621 69.152 -14.309 1.00 10.26 ? 515 TYR A CE1 1 ATOM 4272 C CE2 . TYR A 1 515 ? 73.982 67.584 -13.139 1.00 9.10 ? 515 TYR A CE2 1 ATOM 4273 C CZ . TYR A 1 515 ? 72.840 68.342 -13.221 1.00 11.72 ? 515 TYR A CZ 1 ATOM 4274 O OH . TYR A 1 515 ? 71.921 68.298 -12.201 1.00 12.21 ? 515 TYR A OH 1 ATOM 4275 N N . SER A 1 516 ? 76.524 71.507 -14.882 1.00 11.36 ? 516 SER A N 1 ATOM 4276 C CA . SER A 1 516 ? 77.045 72.206 -13.709 1.00 12.47 ? 516 SER A CA 1 ATOM 4277 C C . SER A 1 516 ? 75.919 72.885 -12.916 1.00 12.94 ? 516 SER A C 1 ATOM 4278 O O . SER A 1 516 ? 75.738 74.110 -12.991 1.00 13.98 ? 516 SER A O 1 ATOM 4279 C CB . SER A 1 516 ? 78.071 73.249 -14.168 1.00 13.39 ? 516 SER A CB 1 ATOM 4280 O OG . SER A 1 516 ? 78.774 73.745 -13.043 1.00 16.40 ? 516 SER A OG 1 ATOM 4281 N N . PRO A 1 517 ? 75.146 72.088 -12.173 1.00 12.76 ? 517 PRO A N 1 ATOM 4282 C CA . PRO A 1 517 ? 73.918 72.608 -11.590 1.00 13.60 ? 517 PRO A CA 1 ATOM 4283 C C . PRO A 1 517 ? 74.145 73.465 -10.358 1.00 14.36 ? 517 PRO A C 1 ATOM 4284 O O . PRO A 1 517 ? 75.084 73.219 -9.603 1.00 16.39 ? 517 PRO A O 1 ATOM 4285 C CB . PRO A 1 517 ? 73.163 71.338 -11.209 1.00 14.15 ? 517 PRO A CB 1 ATOM 4286 C CG . PRO A 1 517 ? 74.211 70.395 -10.883 1.00 13.64 ? 517 PRO A CG 1 ATOM 4287 C CD . PRO A 1 517 ? 75.358 70.667 -11.846 1.00 12.99 ? 517 PRO A CD 1 ATOM 4288 N N . ASP A 1 518 ? 73.354 74.509 -10.250 1.00 14.25 ? 518 ASP A N 1 ATOM 4289 C CA . ASP A 1 518 ? 73.057 75.192 -9.014 1.00 15.38 ? 518 ASP A CA 1 ATOM 4290 C C . ASP A 1 518 ? 71.629 74.776 -8.690 1.00 13.75 ? 518 ASP A C 1 ATOM 4291 O O . ASP A 1 518 ? 70.719 75.042 -9.432 1.00 13.38 ? 518 ASP A O 1 ATOM 4292 C CB . ASP A 1 518 ? 73.140 76.691 -9.294 1.00 16.93 ? 518 ASP A CB 1 ATOM 4293 C CG . ASP A 1 518 ? 72.588 77.568 -8.177 1.00 21.15 ? 518 ASP A CG 1 ATOM 4294 O OD1 . ASP A 1 518 ? 72.078 77.087 -7.145 1.00 21.83 ? 518 ASP A OD1 1 ATOM 4295 O OD2 . ASP A 1 518 ? 72.672 78.788 -8.376 1.00 23.24 ? 518 ASP A OD2 1 ATOM 4296 N N . PHE A 1 519 ? 71.476 74.057 -7.601 1.00 13.65 ? 519 PHE A N 1 ATOM 4297 C CA . PHE A 1 519 ? 70.183 73.420 -7.316 1.00 13.93 ? 519 PHE A CA 1 ATOM 4298 C C . PHE A 1 519 ? 69.110 74.406 -6.913 1.00 14.80 ? 519 PHE A C 1 ATOM 4299 O O . PHE A 1 519 ? 67.967 74.015 -6.740 1.00 15.29 ? 519 PHE A O 1 ATOM 4300 C CB . PHE A 1 519 ? 70.341 72.333 -6.275 1.00 13.67 ? 519 PHE A CB 1 ATOM 4301 C CG . PHE A 1 519 ? 71.189 71.188 -6.733 1.00 11.98 ? 519 PHE A CG 1 ATOM 4302 C CD1 . PHE A 1 519 ? 70.926 70.524 -7.946 1.00 10.70 ? 519 PHE A CD1 1 ATOM 4303 C CD2 . PHE A 1 519 ? 72.257 70.776 -5.973 1.00 13.31 ? 519 PHE A CD2 1 ATOM 4304 C CE1 . PHE A 1 519 ? 71.706 69.452 -8.363 1.00 13.32 ? 519 PHE A CE1 1 ATOM 4305 C CE2 . PHE A 1 519 ? 73.046 69.711 -6.390 1.00 14.10 ? 519 PHE A CE2 1 ATOM 4306 C CZ . PHE A 1 519 ? 72.767 69.044 -7.585 1.00 14.39 ? 519 PHE A CZ 1 ATOM 4307 N N . SER A 1 520 ? 69.472 75.677 -6.783 1.00 14.77 ? 520 SER A N 1 ATOM 4308 C CA . SER A 1 520 ? 68.510 76.722 -6.467 1.00 15.92 ? 520 SER A CA 1 ATOM 4309 C C . SER A 1 520 ? 68.105 77.545 -7.693 1.00 15.22 ? 520 SER A C 1 ATOM 4310 O O . SER A 1 520 ? 67.187 78.341 -7.614 1.00 15.91 ? 520 SER A O 1 ATOM 4311 C CB . SER A 1 520 ? 69.079 77.660 -5.401 1.00 16.92 ? 520 SER A CB 1 ATOM 4312 O OG . SER A 1 520 ? 70.027 78.569 -5.953 1.00 19.48 ? 520 SER A OG 1 ATOM 4313 N N . PHE A 1 521 ? 68.755 77.313 -8.837 1.00 14.72 ? 521 PHE A N 1 ATOM 4314 C CA . PHE A 1 521 ? 68.553 78.143 -10.015 1.00 14.38 ? 521 PHE A CA 1 ATOM 4315 C C . PHE A 1 521 ? 67.394 77.637 -10.873 1.00 14.14 ? 521 PHE A C 1 ATOM 4316 O O . PHE A 1 521 ? 67.120 76.441 -10.900 1.00 14.58 ? 521 PHE A O 1 ATOM 4317 C CB . PHE A 1 521 ? 69.843 78.172 -10.850 1.00 14.82 ? 521 PHE A CB 1 ATOM 4318 C CG . PHE A 1 521 ? 69.797 79.109 -12.040 1.00 16.04 ? 521 PHE A CG 1 ATOM 4319 C CD1 . PHE A 1 521 ? 69.975 80.482 -11.868 1.00 19.94 ? 521 PHE A CD1 1 ATOM 4320 C CD2 . PHE A 1 521 ? 69.622 78.615 -13.340 1.00 18.47 ? 521 PHE A CD2 1 ATOM 4321 C CE1 . PHE A 1 521 ? 69.933 81.360 -12.969 1.00 21.80 ? 521 PHE A CE1 1 ATOM 4322 C CE2 . PHE A 1 521 ? 69.575 79.489 -14.441 1.00 20.22 ? 521 PHE A CE2 1 ATOM 4323 C CZ . PHE A 1 521 ? 69.735 80.856 -14.253 1.00 20.56 ? 521 PHE A CZ 1 ATOM 4324 N N . SER A 1 522 ? 66.736 78.551 -11.576 1.00 13.95 ? 522 SER A N 1 ATOM 4325 C CA A SER A 1 522 ? 65.684 78.194 -12.519 0.50 13.84 ? 522 SER A CA 1 ATOM 4326 C CA B SER A 1 522 ? 65.672 78.233 -12.517 0.50 13.68 ? 522 SER A CA 1 ATOM 4327 C C . SER A 1 522 ? 66.243 78.140 -13.937 1.00 13.28 ? 522 SER A C 1 ATOM 4328 O O . SER A 1 522 ? 66.390 79.166 -14.622 1.00 14.56 ? 522 SER A O 1 ATOM 4329 C CB A SER A 1 522 ? 64.508 79.169 -12.438 0.50 14.32 ? 522 SER A CB 1 ATOM 4330 C CB B SER A 1 522 ? 64.597 79.327 -12.461 0.50 14.07 ? 522 SER A CB 1 ATOM 4331 O OG A SER A 1 522 ? 63.921 79.107 -11.151 0.50 16.53 ? 522 SER A OG 1 ATOM 4332 O OG B SER A 1 522 ? 63.662 79.200 -13.509 0.50 15.51 ? 522 SER A OG 1 ATOM 4333 N N . TYR A 1 523 ? 66.585 76.933 -14.377 1.00 10.72 ? 523 TYR A N 1 ATOM 4334 C CA . TYR A 1 523 ? 67.043 76.718 -15.746 1.00 9.82 ? 523 TYR A CA 1 ATOM 4335 C C . TYR A 1 523 ? 65.927 76.782 -16.755 1.00 10.55 ? 523 TYR A C 1 ATOM 4336 O O . TYR A 1 523 ? 66.144 77.203 -17.901 1.00 9.97 ? 523 TYR A O 1 ATOM 4337 C CB . TYR A 1 523 ? 67.740 75.363 -15.870 1.00 10.49 ? 523 TYR A CB 1 ATOM 4338 C CG . TYR A 1 523 ? 68.996 75.351 -15.072 1.00 10.49 ? 523 TYR A CG 1 ATOM 4339 C CD1 . TYR A 1 523 ? 70.156 75.957 -15.573 1.00 13.51 ? 523 TYR A CD1 1 ATOM 4340 C CD2 . TYR A 1 523 ? 69.033 74.782 -13.805 1.00 10.62 ? 523 TYR A CD2 1 ATOM 4341 C CE1 . TYR A 1 523 ? 71.321 75.981 -14.832 1.00 15.73 ? 523 TYR A CE1 1 ATOM 4342 C CE2 . TYR A 1 523 ? 70.188 74.792 -13.055 1.00 13.73 ? 523 TYR A CE2 1 ATOM 4343 C CZ . TYR A 1 523 ? 71.322 75.412 -13.571 1.00 14.37 ? 523 TYR A CZ 1 ATOM 4344 O OH . TYR A 1 523 ? 72.469 75.422 -12.821 1.00 16.24 ? 523 TYR A OH 1 ATOM 4345 N N . PHE A 1 524 ? 64.723 76.352 -16.354 1.00 8.61 ? 524 PHE A N 1 ATOM 4346 C CA . PHE A 1 524 ? 63.535 76.397 -17.206 1.00 9.27 ? 524 PHE A CA 1 ATOM 4347 C C . PHE A 1 524 ? 62.372 76.887 -16.385 1.00 10.63 ? 524 PHE A C 1 ATOM 4348 O O . PHE A 1 524 ? 62.320 76.629 -15.167 1.00 11.77 ? 524 PHE A O 1 ATOM 4349 C CB . PHE A 1 524 ? 63.143 75.011 -17.759 1.00 8.71 ? 524 PHE A CB 1 ATOM 4350 C CG . PHE A 1 524 ? 64.193 74.371 -18.625 1.00 8.51 ? 524 PHE A CG 1 ATOM 4351 C CD1 . PHE A 1 524 ? 65.229 73.622 -18.056 1.00 9.54 ? 524 PHE A CD1 1 ATOM 4352 C CD2 . PHE A 1 524 ? 64.144 74.509 -20.009 1.00 8.34 ? 524 PHE A CD2 1 ATOM 4353 C CE1 . PHE A 1 524 ? 66.203 73.039 -18.852 1.00 10.45 ? 524 PHE A CE1 1 ATOM 4354 C CE2 . PHE A 1 524 ? 65.102 73.921 -20.811 1.00 9.58 ? 524 PHE A CE2 1 ATOM 4355 C CZ . PHE A 1 524 ? 66.149 73.202 -20.231 1.00 9.82 ? 524 PHE A CZ 1 ATOM 4356 N N . THR A 1 525 ? 61.426 77.526 -17.051 1.00 10.39 ? 525 THR A N 1 ATOM 4357 C CA . THR A 1 525 ? 60.124 77.711 -16.424 1.00 12.58 ? 525 THR A CA 1 ATOM 4358 C C . THR A 1 525 ? 59.088 76.926 -17.177 1.00 11.38 ? 525 THR A C 1 ATOM 4359 O O . THR A 1 525 ? 59.180 76.764 -18.389 1.00 11.83 ? 525 THR A O 1 ATOM 4360 C CB . THR A 1 525 ? 59.697 79.173 -16.394 1.00 13.85 ? 525 THR A CB 1 ATOM 4361 O OG1 . THR A 1 525 ? 59.719 79.670 -17.724 1.00 17.67 ? 525 THR A OG1 1 ATOM 4362 C CG2 . THR A 1 525 ? 60.698 80.065 -15.661 1.00 17.26 ? 525 THR A CG2 1 ATOM 4363 N N . LEU A 1 526 ? 58.103 76.420 -16.460 1.00 9.99 ? 526 LEU A N 1 ATOM 4364 C CA . LEU A 1 526 ? 57.006 75.734 -17.085 1.00 11.26 ? 526 LEU A CA 1 ATOM 4365 C C . LEU A 1 526 ? 56.081 76.739 -17.739 1.00 11.81 ? 526 LEU A C 1 ATOM 4366 O O . LEU A 1 526 ? 55.844 77.829 -17.208 1.00 13.92 ? 526 LEU A O 1 ATOM 4367 C CB . LEU A 1 526 ? 56.247 74.883 -16.048 1.00 12.13 ? 526 LEU A CB 1 ATOM 4368 C CG . LEU A 1 526 ? 56.802 73.502 -15.711 1.00 14.61 ? 526 LEU A CG 1 ATOM 4369 C CD1 . LEU A 1 526 ? 56.126 73.034 -14.422 1.00 16.54 ? 526 LEU A CD1 1 ATOM 4370 C CD2 . LEU A 1 526 ? 56.534 72.511 -16.835 1.00 17.11 ? 526 LEU A CD2 1 ATOM 4371 N N . ASP A 1 527 ? 55.530 76.359 -18.879 1.00 9.72 ? 527 ASP A N 1 ATOM 4372 C CA . ASP A 1 527 ? 54.524 77.160 -19.536 1.00 11.82 ? 527 ASP A CA 1 ATOM 4373 C C . ASP A 1 527 ? 53.284 76.271 -19.628 1.00 11.59 ? 527 ASP A C 1 ATOM 4374 O O . ASP A 1 527 ? 53.324 75.194 -20.180 1.00 14.85 ? 527 ASP A O 1 ATOM 4375 C CB . ASP A 1 527 ? 55.001 77.546 -20.950 1.00 12.29 ? 527 ASP A CB 1 ATOM 4376 C CG . ASP A 1 527 ? 53.984 78.395 -21.702 1.00 16.44 ? 527 ASP A CG 1 ATOM 4377 O OD1 . ASP A 1 527 ? 53.590 79.455 -21.178 1.00 21.44 ? 527 ASP A OD1 1 ATOM 4378 O OD2 . ASP A 1 527 ? 53.509 78.074 -22.813 1.00 20.79 ? 527 ASP A OD2 1 ATOM 4379 N N . ASP A 1 528 ? 52.201 76.698 -19.013 1.00 12.16 ? 528 ASP A N 1 ATOM 4380 C CA . ASP A 1 528 ? 50.990 75.911 -19.046 1.00 11.49 ? 528 ASP A CA 1 ATOM 4381 C C . ASP A 1 528 ? 49.906 76.770 -19.649 1.00 11.90 ? 528 ASP A C 1 ATOM 4382 O O . ASP A 1 528 ? 49.552 77.816 -19.119 1.00 11.84 ? 528 ASP A O 1 ATOM 4383 C CB . ASP A 1 528 ? 50.654 75.459 -17.633 1.00 11.10 ? 528 ASP A CB 1 ATOM 4384 C CG . ASP A 1 528 ? 49.638 74.354 -17.604 1.00 12.31 ? 528 ASP A CG 1 ATOM 4385 O OD1 . ASP A 1 528 ? 48.634 74.382 -18.357 1.00 14.08 ? 528 ASP A OD1 1 ATOM 4386 O OD2 . ASP A 1 528 ? 49.800 73.383 -16.842 1.00 14.53 ? 528 ASP A OD2 1 ATOM 4387 N N . SER A 1 529 ? 49.392 76.316 -20.786 1.00 11.92 ? 529 SER A N 1 ATOM 4388 C CA . SER A 1 529 ? 48.337 77.018 -21.526 1.00 13.98 ? 529 SER A CA 1 ATOM 4389 C C . SER A 1 529 ? 46.977 76.917 -20.888 1.00 13.63 ? 529 SER A C 1 ATOM 4390 O O . SER A 1 529 ? 46.096 77.688 -21.214 1.00 15.08 ? 529 SER A O 1 ATOM 4391 C CB . SER A 1 529 ? 48.210 76.456 -22.938 1.00 15.52 ? 529 SER A CB 1 ATOM 4392 O OG . SER A 1 529 ? 49.426 76.639 -23.617 1.00 19.69 ? 529 SER A OG 1 ATOM 4393 N N . ARG A 1 530 ? 46.763 75.938 -20.014 1.00 11.72 ? 530 ARG A N 1 ATOM 4394 C CA . ARG A 1 530 ? 45.409 75.683 -19.537 1.00 12.03 ? 530 ARG A CA 1 ATOM 4395 C C . ARG A 1 530 ? 45.272 75.744 -18.062 1.00 12.96 ? 530 ARG A C 1 ATOM 4396 O O . ARG A 1 530 ? 44.230 75.360 -17.540 1.00 15.13 ? 530 ARG A O 1 ATOM 4397 C CB . ARG A 1 530 ? 44.917 74.313 -20.032 1.00 12.16 ? 530 ARG A CB 1 ATOM 4398 C CG . ARG A 1 530 ? 44.914 74.243 -21.558 1.00 11.33 ? 530 ARG A CG 1 ATOM 4399 C CD . ARG A 1 530 ? 44.239 73.025 -22.149 1.00 12.57 ? 530 ARG A CD 1 ATOM 4400 N NE . ARG A 1 530 ? 44.893 71.816 -21.661 1.00 12.86 ? 530 ARG A NE 1 ATOM 4401 C CZ . ARG A 1 530 ? 44.722 70.615 -22.210 1.00 13.94 ? 530 ARG A CZ 1 ATOM 4402 N NH1 . ARG A 1 530 ? 43.926 70.476 -23.266 1.00 15.28 ? 530 ARG A NH1 1 ATOM 4403 N NH2 . ARG A 1 530 ? 45.344 69.568 -21.686 1.00 14.01 ? 530 ARG A NH2 1 ATOM 4404 N N . TRP A 1 531 ? 46.296 76.214 -17.368 1.00 10.85 ? 531 TRP A N 1 ATOM 4405 C CA . TRP A 1 531 ? 46.174 76.462 -15.928 1.00 12.11 ? 531 TRP A CA 1 ATOM 4406 C C . TRP A 1 531 ? 47.072 77.626 -15.489 1.00 13.21 ? 531 TRP A C 1 ATOM 4407 O O . TRP A 1 531 ? 48.273 77.566 -15.724 1.00 12.39 ? 531 TRP A O 1 ATOM 4408 C CB . TRP A 1 531 ? 46.529 75.228 -15.078 1.00 12.82 ? 531 TRP A CB 1 ATOM 4409 C CG . TRP A 1 531 ? 46.433 75.610 -13.638 1.00 14.12 ? 531 TRP A CG 1 ATOM 4410 C CD1 . TRP A 1 531 ? 47.464 76.034 -12.812 1.00 15.56 ? 531 TRP A CD1 1 ATOM 4411 C CD2 . TRP A 1 531 ? 45.243 75.691 -12.874 1.00 15.38 ? 531 TRP A CD2 1 ATOM 4412 N NE1 . TRP A 1 531 ? 46.962 76.341 -11.571 1.00 18.20 ? 531 TRP A NE1 1 ATOM 4413 C CE2 . TRP A 1 531 ? 45.603 76.148 -11.580 1.00 13.78 ? 531 TRP A CE2 1 ATOM 4414 C CE3 . TRP A 1 531 ? 43.911 75.409 -13.139 1.00 16.20 ? 531 TRP A CE3 1 ATOM 4415 C CZ2 . TRP A 1 531 ? 44.671 76.318 -10.559 1.00 15.45 ? 531 TRP A CZ2 1 ATOM 4416 C CZ3 . TRP A 1 531 ? 42.970 75.605 -12.124 1.00 15.88 ? 531 TRP A CZ3 1 ATOM 4417 C CH2 . TRP A 1 531 ? 43.364 76.049 -10.850 1.00 16.77 ? 531 TRP A CH2 1 ATOM 4418 N N . PRO A 1 532 ? 46.521 78.669 -14.883 1.00 14.04 ? 532 PRO A N 1 ATOM 4419 C CA . PRO A 1 532 ? 45.122 78.751 -14.469 1.00 15.34 ? 532 PRO A CA 1 ATOM 4420 C C . PRO A 1 532 ? 44.193 79.080 -15.618 1.00 17.67 ? 532 PRO A C 1 ATOM 4421 O O . PRO A 1 532 ? 43.006 78.978 -15.471 1.00 18.28 ? 532 PRO A O 1 ATOM 4422 C CB . PRO A 1 532 ? 45.126 79.931 -13.475 1.00 15.15 ? 532 PRO A CB 1 ATOM 4423 C CG . PRO A 1 532 ? 46.475 79.982 -12.974 1.00 17.54 ? 532 PRO A CG 1 ATOM 4424 C CD . PRO A 1 532 ? 47.354 79.627 -14.141 1.00 14.95 ? 532 PRO A CD 1 ATOM 4425 N N . GLY A 1 533 ? 44.757 79.463 -16.750 1.00 19.69 ? 533 GLY A N 1 ATOM 4426 C CA . GLY A 1 533 ? 43.981 79.610 -17.964 1.00 23.55 ? 533 GLY A CA 1 ATOM 4427 C C . GLY A 1 533 ? 43.654 81.054 -18.293 1.00 27.34 ? 533 GLY A C 1 ATOM 4428 O O . GLY A 1 533 ? 43.600 81.909 -17.407 1.00 27.12 ? 533 GLY A O 1 ATOM 4429 N N . SER A 1 534 ? 43.469 81.305 -19.592 1.00 30.47 ? 534 SER A N 1 ATOM 4430 C CA . SER A 1 534 ? 43.318 82.650 -20.164 1.00 33.59 ? 534 SER A CA 1 ATOM 4431 C C . SER A 1 534 ? 42.150 83.200 -19.372 1.00 35.15 ? 534 SER A C 1 ATOM 4432 O O . SER A 1 534 ? 41.121 82.540 -19.312 1.00 36.08 ? 534 SER A O 1 ATOM 4433 C CB . SER A 1 534 ? 42.847 82.532 -21.632 1.00 34.03 ? 534 SER A CB 1 ATOM 4434 O OG . SER A 1 534 ? 43.841 82.889 -22.581 1.00 35.99 ? 534 SER A OG 1 ATOM 4435 N N . GLY A 1 535 ? 42.276 84.373 -18.771 1.00 36.55 ? 535 GLY A N 1 ATOM 4436 C CA . GLY A 1 535 ? 41.141 84.979 -18.087 1.00 38.06 ? 535 GLY A CA 1 ATOM 4437 C C . GLY A 1 535 ? 40.974 84.526 -16.646 1.00 39.23 ? 535 GLY A C 1 ATOM 4438 O O . GLY A 1 535 ? 40.103 84.996 -15.887 1.00 39.06 ? 535 GLY A O 1 ATOM 4439 N N . VAL A 1 536 ? 41.823 83.581 -16.261 1.00 40.29 ? 536 VAL A N 1 ATOM 4440 C CA . VAL A 1 536 ? 41.930 83.184 -14.870 1.00 41.42 ? 536 VAL A CA 1 ATOM 4441 C C . VAL A 1 536 ? 43.085 83.984 -14.253 1.00 42.40 ? 536 VAL A C 1 ATOM 4442 O O . VAL A 1 536 ? 42.946 84.619 -13.208 1.00 42.48 ? 536 VAL A O 1 ATOM 4443 C CB . VAL A 1 536 ? 42.207 81.676 -14.779 1.00 41.71 ? 536 VAL A CB 1 ATOM 4444 C CG1 . VAL A 1 536 ? 41.382 81.030 -13.681 1.00 40.82 ? 536 VAL A CG1 1 ATOM 4445 C CG2 . VAL A 1 536 ? 41.930 81.002 -16.113 1.00 41.81 ? 536 VAL A CG2 1 ATOM 4446 N N . GLU A 1 537 ? 44.211 83.979 -14.950 1.00 42.95 ? 537 GLU A N 1 ATOM 4447 C CA . GLU A 1 537 ? 45.448 84.589 -14.470 1.00 43.49 ? 537 GLU A CA 1 ATOM 4448 C C . GLU A 1 537 ? 46.336 84.899 -15.664 1.00 43.09 ? 537 GLU A C 1 ATOM 4449 O O . GLU A 1 537 ? 46.475 84.060 -16.562 1.00 43.27 ? 537 GLU A O 1 ATOM 4450 C CB . GLU A 1 537 ? 46.179 83.617 -13.538 1.00 43.42 ? 537 GLU A CB 1 ATOM 4451 C CG . GLU A 1 537 ? 47.485 84.129 -12.948 1.00 44.29 ? 537 GLU A CG 1 ATOM 4452 C CD . GLU A 1 537 ? 47.938 83.317 -11.743 1.00 44.85 ? 537 GLU A CD 1 ATOM 4453 O OE1 . GLU A 1 537 ? 47.227 83.334 -10.708 1.00 45.82 ? 537 GLU A OE1 1 ATOM 4454 O OE2 . GLU A 1 537 ? 49.011 82.664 -11.823 1.00 46.84 ? 537 GLU A OE2 1 ATOM 4455 N N . ASP A 1 538 ? 46.899 86.105 -15.739 1.00 42.74 ? 538 ASP A N 1 ATOM 4456 C CA . ASP A 1 538 ? 48.089 86.266 -16.587 1.00 42.19 ? 538 ASP A CA 1 ATOM 4457 C C . ASP A 1 538 ? 49.296 85.743 -15.856 1.00 41.09 ? 538 ASP A C 1 ATOM 4458 O O . ASP A 1 538 ? 49.878 86.404 -15.010 1.00 41.42 ? 538 ASP A O 1 ATOM 4459 C CB . ASP A 1 538 ? 48.327 87.678 -17.170 1.00 42.49 ? 538 ASP A CB 1 ATOM 4460 C CG . ASP A 1 538 ? 49.138 87.634 -18.479 1.00 43.64 ? 538 ASP A CG 1 ATOM 4461 O OD1 . ASP A 1 538 ? 49.273 86.531 -19.035 1.00 43.81 ? 538 ASP A OD1 1 ATOM 4462 O OD2 . ASP A 1 538 ? 49.625 88.684 -18.981 1.00 44.77 ? 538 ASP A OD2 1 ATOM 4463 N N . SER A 1 539 ? 49.692 84.527 -16.208 1.00 39.29 ? 539 SER A N 1 ATOM 4464 C CA . SER A 1 539 ? 50.888 83.959 -15.630 1.00 37.41 ? 539 SER A CA 1 ATOM 4465 C C . SER A 1 539 ? 51.819 83.478 -16.717 1.00 35.49 ? 539 SER A C 1 ATOM 4466 O O . SER A 1 539 ? 52.942 83.081 -16.431 1.00 36.31 ? 539 SER A O 1 ATOM 4467 C CB . SER A 1 539 ? 50.553 82.835 -14.670 1.00 37.80 ? 539 SER A CB 1 ATOM 4468 O OG . SER A 1 539 ? 50.023 81.732 -15.370 1.00 38.03 ? 539 SER A OG 1 ATOM 4469 N N . ARG A 1 540 ? 51.331 83.532 -17.956 1.00 32.53 ? 540 ARG A N 1 ATOM 4470 C CA . ARG A 1 540 ? 52.053 82.996 -19.095 1.00 28.60 ? 540 ARG A CA 1 ATOM 4471 C C . ARG A 1 540 ? 53.129 83.943 -19.525 1.00 26.38 ? 540 ARG A C 1 ATOM 4472 O O . ARG A 1 540 ? 52.858 85.079 -19.871 1.00 26.31 ? 540 ARG A O 1 ATOM 4473 C CB . ARG A 1 540 ? 51.136 82.672 -20.264 1.00 28.36 ? 540 ARG A CB 1 ATOM 4474 C CG . ARG A 1 540 ? 50.493 81.311 -20.118 1.00 26.96 ? 540 ARG A CG 1 ATOM 4475 C CD . ARG A 1 540 ? 49.841 80.860 -21.371 1.00 21.47 ? 540 ARG A CD 1 ATOM 4476 N NE . ARG A 1 540 ? 50.781 80.119 -22.183 1.00 16.77 ? 540 ARG A NE 1 ATOM 4477 C CZ . ARG A 1 540 ? 50.495 79.636 -23.375 1.00 16.48 ? 540 ARG A CZ 1 ATOM 4478 N NH1 . ARG A 1 540 ? 49.296 79.831 -23.892 1.00 13.86 ? 540 ARG A NH1 1 ATOM 4479 N NH2 . ARG A 1 540 ? 51.410 78.982 -24.042 1.00 16.80 ? 540 ARG A NH2 1 ATOM 4480 N N . THR A 1 541 ? 54.350 83.438 -19.485 1.00 23.86 ? 541 THR A N 1 ATOM 4481 C CA . THR A 1 541 ? 55.500 84.190 -19.893 1.00 21.94 ? 541 THR A CA 1 ATOM 4482 C C . THR A 1 541 ? 55.549 84.261 -21.401 1.00 19.55 ? 541 THR A C 1 ATOM 4483 O O . THR A 1 541 ? 55.192 83.328 -22.083 1.00 20.33 ? 541 THR A O 1 ATOM 4484 C CB . THR A 1 541 ? 56.809 83.643 -19.285 1.00 23.03 ? 541 THR A CB 1 ATOM 4485 O OG1 . THR A 1 541 ? 57.517 82.861 -20.243 1.00 24.77 ? 541 THR A OG1 1 ATOM 4486 C CG2 . THR A 1 541 ? 56.538 82.807 -18.038 1.00 23.03 ? 541 THR A CG2 1 ATOM 4487 N N . THR A 1 542 ? 55.946 85.417 -21.900 1.00 16.51 ? 542 THR A N 1 ATOM 4488 C CA . THR A 1 542 ? 56.183 85.614 -23.308 1.00 14.20 ? 542 THR A CA 1 ATOM 4489 C C . THR A 1 542 ? 57.655 85.358 -23.566 1.00 12.23 ? 542 THR A C 1 ATOM 4490 O O . THR A 1 542 ? 58.517 85.836 -22.797 1.00 13.18 ? 542 THR A O 1 ATOM 4491 C CB . THR A 1 542 ? 55.818 87.048 -23.663 1.00 14.87 ? 542 THR A CB 1 ATOM 4492 O OG1 . THR A 1 542 ? 54.419 87.228 -23.413 1.00 17.39 ? 542 THR A OG1 1 ATOM 4493 C CG2 . THR A 1 542 ? 55.984 87.309 -25.161 1.00 14.91 ? 542 THR A CG2 1 ATOM 4494 N N . ILE A 1 543 ? 57.942 84.607 -24.623 1.00 10.82 ? 543 ILE A N 1 ATOM 4495 C CA . ILE A 1 543 ? 59.324 84.436 -25.066 1.00 10.01 ? 543 ILE A CA 1 ATOM 4496 C C . ILE A 1 543 ? 59.699 85.717 -25.827 1.00 10.88 ? 543 ILE A C 1 ATOM 4497 O O . ILE A 1 543 ? 59.054 86.041 -26.827 1.00 11.46 ? 543 ILE A O 1 ATOM 4498 C CB . ILE A 1 543 ? 59.433 83.223 -25.952 1.00 10.44 ? 543 ILE A CB 1 ATOM 4499 C CG1 . ILE A 1 543 ? 59.146 81.943 -25.129 1.00 9.94 ? 543 ILE A CG1 1 ATOM 4500 C CG2 . ILE A 1 543 ? 60.819 83.201 -26.687 1.00 10.62 ? 543 ILE A CG2 1 ATOM 4501 C CD1 . ILE A 1 543 ? 59.030 80.691 -25.972 1.00 10.49 ? 543 ILE A CD1 1 ATOM 4502 N N . ILE A 1 544 ? 60.684 86.443 -25.291 1.00 11.41 ? 544 ILE A N 1 ATOM 4503 C CA . ILE A 1 544 ? 61.072 87.736 -25.850 1.00 12.09 ? 544 ILE A CA 1 ATOM 4504 C C . ILE A 1 544 ? 62.259 87.554 -26.782 1.00 12.83 ? 544 ILE A C 1 ATOM 4505 O O . ILE A 1 544 ? 63.362 87.187 -26.365 1.00 12.99 ? 544 ILE A O 1 ATOM 4506 C CB . ILE A 1 544 ? 61.329 88.738 -24.725 1.00 13.43 ? 544 ILE A CB 1 ATOM 4507 C CG1 . ILE A 1 544 ? 60.014 88.990 -23.983 1.00 15.95 ? 544 ILE A CG1 1 ATOM 4508 C CG2 . ILE A 1 544 ? 61.851 90.036 -25.297 1.00 14.28 ? 544 ILE A CG2 1 ATOM 4509 C CD1 . ILE A 1 544 ? 60.108 89.995 -22.847 1.00 20.80 ? 544 ILE A CD1 1 ATOM 4510 N N . LEU A 1 545 ? 61.984 87.740 -28.063 1.00 12.33 ? 545 LEU A N 1 ATOM 4511 C CA . LEU A 1 545 ? 63.001 87.642 -29.095 1.00 12.50 ? 545 LEU A CA 1 ATOM 4512 C C . LEU A 1 545 ? 63.137 88.998 -29.767 1.00 12.44 ? 545 LEU A C 1 ATOM 4513 O O . LEU A 1 545 ? 62.192 89.769 -29.796 1.00 13.18 ? 545 LEU A O 1 ATOM 4514 C CB . LEU A 1 545 ? 62.620 86.572 -30.114 1.00 12.28 ? 545 LEU A CB 1 ATOM 4515 C CG . LEU A 1 545 ? 62.430 85.145 -29.566 1.00 13.41 ? 545 LEU A CG 1 ATOM 4516 C CD1 . LEU A 1 545 ? 61.982 84.208 -30.664 1.00 14.86 ? 545 LEU A CD1 1 ATOM 4517 C CD2 . LEU A 1 545 ? 63.702 84.602 -28.922 1.00 13.13 ? 545 LEU A CD2 1 ATOM 4518 N N . GLY A 1 546 ? 64.300 89.264 -30.336 1.00 12.95 ? 546 GLY A N 1 ATOM 4519 C CA . GLY A 1 546 ? 64.494 90.525 -31.035 1.00 13.02 ? 546 GLY A CA 1 ATOM 4520 C C . GLY A 1 546 ? 65.889 90.548 -31.581 1.00 13.50 ? 546 GLY A C 1 ATOM 4521 O O . GLY A 1 546 ? 66.818 89.999 -30.993 1.00 12.06 ? 546 GLY A O 1 ATOM 4522 N N . GLU A 1 547 ? 66.036 91.234 -32.706 1.00 14.99 ? 547 GLU A N 1 ATOM 4523 C CA . GLU A 1 547 ? 67.343 91.387 -33.340 1.00 17.43 ? 547 GLU A CA 1 ATOM 4524 C C . GLU A 1 547 ? 68.389 92.023 -32.422 1.00 17.37 ? 547 GLU A C 1 ATOM 4525 O O . GLU A 1 547 ? 69.577 91.685 -32.479 1.00 18.54 ? 547 GLU A O 1 ATOM 4526 C CB . GLU A 1 547 ? 67.169 92.247 -34.577 1.00 18.74 ? 547 GLU A CB 1 ATOM 4527 C CG . GLU A 1 547 ? 68.410 92.455 -35.426 1.00 25.50 ? 547 GLU A CG 1 ATOM 4528 C CD . GLU A 1 547 ? 68.088 93.224 -36.695 1.00 31.90 ? 547 GLU A CD 1 ATOM 4529 O OE1 . GLU A 1 547 ? 66.884 93.308 -37.035 1.00 34.67 ? 547 GLU A OE1 1 ATOM 4530 O OE2 . GLU A 1 547 ? 69.026 93.746 -37.351 1.00 35.90 ? 547 GLU A OE2 1 ATOM 4531 N N . ASP A 1 548 ? 67.933 92.937 -31.571 1.00 16.27 ? 548 ASP A N 1 ATOM 4532 C CA . ASP A 1 548 ? 68.834 93.612 -30.650 1.00 16.88 ? 548 ASP A CA 1 ATOM 4533 C C . ASP A 1 548 ? 68.783 93.058 -29.241 1.00 17.50 ? 548 ASP A C 1 ATOM 4534 O O . ASP A 1 548 ? 69.178 93.749 -28.290 1.00 19.22 ? 548 ASP A O 1 ATOM 4535 C CB . ASP A 1 548 ? 68.538 95.111 -30.616 1.00 16.50 ? 548 ASP A CB 1 ATOM 4536 C CG . ASP A 1 548 ? 68.648 95.750 -31.967 1.00 18.88 ? 548 ASP A CG 1 ATOM 4537 O OD1 . ASP A 1 548 ? 69.775 95.778 -32.506 1.00 23.41 ? 548 ASP A OD1 1 ATOM 4538 O OD2 . ASP A 1 548 ? 67.673 96.261 -32.567 1.00 22.31 ? 548 ASP A OD2 1 ATOM 4539 N N . ILE A 1 549 ? 68.330 91.816 -29.079 1.00 16.11 ? 549 ILE A N 1 ATOM 4540 C CA . ILE A 1 549 ? 68.321 91.217 -27.735 1.00 15.66 ? 549 ILE A CA 1 ATOM 4541 C C . ILE A 1 549 ? 68.622 89.722 -27.705 1.00 14.75 ? 549 ILE A C 1 ATOM 4542 O O . ILE A 1 549 ? 69.473 89.297 -26.940 1.00 14.72 ? 549 ILE A O 1 ATOM 4543 C CB . ILE A 1 549 ? 67.019 91.555 -26.938 1.00 15.64 ? 549 ILE A CB 1 ATOM 4544 C CG1 . ILE A 1 549 ? 67.147 90.997 -25.497 1.00 16.19 ? 549 ILE A CG1 1 ATOM 4545 C CG2 . ILE A 1 549 ? 65.742 91.106 -27.692 1.00 14.44 ? 549 ILE A CG2 1 ATOM 4546 C CD1 . ILE A 1 549 ? 66.037 91.373 -24.524 1.00 17.90 ? 549 ILE A CD1 1 ATOM 4547 N N . LEU A 1 550 ? 67.945 88.958 -28.556 1.00 13.49 ? 550 LEU A N 1 ATOM 4548 C CA . LEU A 1 550 ? 68.007 87.499 -28.469 1.00 12.72 ? 550 LEU A CA 1 ATOM 4549 C C . LEU A 1 550 ? 67.333 86.910 -29.688 1.00 11.75 ? 550 LEU A C 1 ATOM 4550 O O . LEU A 1 550 ? 66.144 87.119 -29.883 1.00 12.43 ? 550 LEU A O 1 ATOM 4551 C CB . LEU A 1 550 ? 67.273 87.019 -27.203 1.00 12.98 ? 550 LEU A CB 1 ATOM 4552 C CG . LEU A 1 550 ? 67.411 85.512 -26.945 1.00 14.55 ? 550 LEU A CG 1 ATOM 4553 C CD1 . LEU A 1 550 ? 68.858 85.201 -26.612 1.00 14.89 ? 550 LEU A CD1 1 ATOM 4554 C CD2 . LEU A 1 550 ? 66.490 85.128 -25.821 1.00 14.34 ? 550 LEU A CD2 1 ATOM 4555 N N . PRO A 1 551 ? 68.084 86.252 -30.569 1.00 11.13 ? 551 PRO A N 1 ATOM 4556 C CA . PRO A 1 551 ? 67.475 85.703 -31.784 1.00 12.48 ? 551 PRO A CA 1 ATOM 4557 C C . PRO A 1 551 ? 66.634 84.452 -31.614 1.00 11.31 ? 551 PRO A C 1 ATOM 4558 O O . PRO A 1 551 ? 65.788 84.202 -32.466 1.00 12.80 ? 551 PRO A O 1 ATOM 4559 C CB . PRO A 1 551 ? 68.679 85.392 -32.690 1.00 13.26 ? 551 PRO A CB 1 ATOM 4560 C CG . PRO A 1 551 ? 69.815 85.264 -31.817 1.00 15.49 ? 551 PRO A CG 1 ATOM 4561 C CD . PRO A 1 551 ? 69.558 86.175 -30.604 1.00 13.22 ? 551 PRO A CD 1 ATOM 4562 N N . SER A 1 552 ? 66.928 83.649 -30.598 1.00 10.89 ? 552 SER A N 1 ATOM 4563 C CA . SER A 1 552 ? 66.278 82.347 -30.559 1.00 10.43 ? 552 SER A CA 1 ATOM 4564 C C . SER A 1 552 ? 66.171 81.858 -29.141 1.00 9.90 ? 552 SER A C 1 ATOM 4565 O O . SER A 1 552 ? 66.816 82.386 -28.244 1.00 9.12 ? 552 SER A O 1 ATOM 4566 C CB . SER A 1 552 ? 67.039 81.328 -31.397 1.00 12.25 ? 552 SER A CB 1 ATOM 4567 O OG . SER A 1 552 ? 68.265 81.005 -30.797 1.00 15.97 ? 552 SER A OG 1 ATOM 4568 N N . LYS A 1 553 ? 65.299 80.869 -28.959 1.00 8.79 ? 553 LYS A N 1 ATOM 4569 C CA . LYS A 1 553 ? 65.019 80.307 -27.635 1.00 9.14 ? 553 LYS A CA 1 ATOM 4570 C C . LYS A 1 553 ? 64.753 78.803 -27.730 1.00 8.37 ? 553 LYS A C 1 ATOM 4571 O O . LYS A 1 553 ? 63.975 78.370 -28.569 1.00 8.31 ? 553 LYS A O 1 ATOM 4572 C CB . LYS A 1 553 ? 63.772 80.986 -27.079 1.00 8.72 ? 553 LYS A CB 1 ATOM 4573 C CG . LYS A 1 553 ? 63.267 80.414 -25.730 1.00 10.02 ? 553 LYS A CG 1 ATOM 4574 C CD . LYS A 1 553 ? 64.297 80.578 -24.670 1.00 12.07 ? 553 LYS A CD 1 ATOM 4575 C CE . LYS A 1 553 ? 64.539 82.034 -24.239 1.00 12.97 ? 553 LYS A CE 1 ATOM 4576 N NZ . LYS A 1 553 ? 65.710 82.069 -23.274 1.00 12.80 ? 553 LYS A NZ 1 ATOM 4577 N N . HIS A 1 554 ? 65.417 78.047 -26.862 1.00 8.49 ? 554 HIS A N 1 ATOM 4578 C CA . HIS A 1 554 ? 65.113 76.620 -26.716 1.00 9.07 ? 554 HIS A CA 1 ATOM 4579 C C . HIS A 1 554 ? 63.900 76.391 -25.828 1.00 8.72 ? 554 HIS A C 1 ATOM 4580 O O . HIS A 1 554 ? 63.759 77.006 -24.779 1.00 9.34 ? 554 HIS A O 1 ATOM 4581 C CB . HIS A 1 554 ? 66.304 75.910 -26.105 1.00 9.48 ? 554 HIS A CB 1 ATOM 4582 C CG . HIS A 1 554 ? 67.459 75.714 -27.041 1.00 12.31 ? 554 HIS A CG 1 ATOM 4583 N ND1 . HIS A 1 554 ? 68.123 76.758 -27.655 1.00 19.56 ? 554 HIS A ND1 1 ATOM 4584 C CD2 . HIS A 1 554 ? 68.080 74.581 -27.453 1.00 16.15 ? 554 HIS A CD2 1 ATOM 4585 C CE1 . HIS A 1 554 ? 69.108 76.277 -28.396 1.00 19.74 ? 554 HIS A CE1 1 ATOM 4586 N NE2 . HIS A 1 554 ? 69.109 74.958 -28.286 1.00 15.70 ? 554 HIS A NE2 1 ATOM 4587 N N . VAL A 1 555 ? 63.053 75.475 -26.285 1.00 7.54 ? 555 VAL A N 1 ATOM 4588 C CA . VAL A 1 555 ? 61.932 74.969 -25.496 1.00 7.74 ? 555 VAL A CA 1 ATOM 4589 C C . VAL A 1 555 ? 62.017 73.453 -25.486 1.00 7.70 ? 555 VAL A C 1 ATOM 4590 O O . VAL A 1 555 ? 62.509 72.831 -26.431 1.00 7.89 ? 555 VAL A O 1 ATOM 4591 C CB . VAL A 1 555 ? 60.588 75.457 -26.045 1.00 6.98 ? 555 VAL A CB 1 ATOM 4592 C CG1 . VAL A 1 555 ? 60.532 76.965 -25.968 1.00 9.15 ? 555 VAL A CG1 1 ATOM 4593 C CG2 . VAL A 1 555 ? 60.375 74.997 -27.473 1.00 8.23 ? 555 VAL A CG2 1 ATOM 4594 N N . VAL A 1 556 ? 61.500 72.848 -24.416 1.00 6.80 ? 556 VAL A N 1 ATOM 4595 C CA . VAL A 1 556 ? 61.565 71.402 -24.269 1.00 7.08 ? 556 VAL A CA 1 ATOM 4596 C C . VAL A 1 556 ? 60.181 70.886 -23.863 1.00 5.96 ? 556 VAL A C 1 ATOM 4597 O O . VAL A 1 556 ? 59.534 71.493 -23.006 1.00 5.75 ? 556 VAL A O 1 ATOM 4598 C CB . VAL A 1 556 ? 62.561 71.017 -23.164 1.00 6.96 ? 556 VAL A CB 1 ATOM 4599 C CG1 . VAL A 1 556 ? 62.505 69.487 -22.887 1.00 7.75 ? 556 VAL A CG1 1 ATOM 4600 C CG2 . VAL A 1 556 ? 63.979 71.472 -23.519 1.00 9.07 ? 556 VAL A CG2 1 ATOM 4601 N N . MET A 1 557 ? 59.771 69.792 -24.491 1.00 5.97 ? 557 MET A N 1 ATOM 4602 C CA . MET A 1 557 ? 58.503 69.102 -24.130 1.00 6.55 ? 557 MET A CA 1 ATOM 4603 C C . MET A 1 557 ? 58.804 67.776 -23.457 1.00 6.70 ? 557 MET A C 1 ATOM 4604 O O . MET A 1 557 ? 59.677 67.044 -23.885 1.00 7.03 ? 557 MET A O 1 ATOM 4605 C CB . MET A 1 557 ? 57.607 68.857 -25.355 1.00 7.28 ? 557 MET A CB 1 ATOM 4606 C CG . MET A 1 557 ? 56.600 69.970 -25.656 1.00 8.40 ? 557 MET A CG 1 ATOM 4607 S SD . MET A 1 557 ? 57.325 71.625 -25.859 1.00 10.70 ? 557 MET A SD 1 ATOM 4608 C CE . MET A 1 557 ? 58.313 71.461 -27.311 1.00 13.40 ? 557 MET A CE 1 ATOM 4609 N N . HIS A 1 558 ? 58.036 67.501 -22.403 1.00 6.17 ? 558 HIS A N 1 ATOM 4610 C CA . HIS A 1 558 ? 58.092 66.207 -21.727 1.00 5.41 ? 558 HIS A CA 1 ATOM 4611 C C . HIS A 1 558 ? 56.831 65.431 -21.954 1.00 5.69 ? 558 HIS A C 1 ATOM 4612 O O . HIS A 1 558 ? 55.749 66.018 -21.955 1.00 6.77 ? 558 HIS A O 1 ATOM 4613 C CB . HIS A 1 558 ? 58.278 66.411 -20.229 1.00 6.86 ? 558 HIS A CB 1 ATOM 4614 C CG . HIS A 1 558 ? 58.215 65.143 -19.441 1.00 5.79 ? 558 HIS A CG 1 ATOM 4615 N ND1 . HIS A 1 558 ? 57.272 64.933 -18.459 1.00 6.29 ? 558 HIS A ND1 1 ATOM 4616 C CD2 . HIS A 1 558 ? 58.972 64.016 -19.489 1.00 6.14 ? 558 HIS A CD2 1 ATOM 4617 C CE1 . HIS A 1 558 ? 57.501 63.758 -17.893 1.00 6.24 ? 558 HIS A CE1 1 ATOM 4618 N NE2 . HIS A 1 558 ? 58.503 63.159 -18.509 1.00 6.96 ? 558 HIS A NE2 1 ATOM 4619 N N . ASN A 1 559 ? 56.984 64.117 -22.169 1.00 5.49 ? 559 ASN A N 1 ATOM 4620 C CA . ASN A 1 559 ? 55.841 63.232 -22.376 1.00 5.73 ? 559 ASN A CA 1 ATOM 4621 C C . ASN A 1 559 ? 55.842 62.122 -21.331 1.00 5.99 ? 559 ASN A C 1 ATOM 4622 O O . ASN A 1 559 ? 56.658 61.228 -21.410 1.00 6.70 ? 559 ASN A O 1 ATOM 4623 C CB . ASN A 1 559 ? 55.949 62.592 -23.761 1.00 6.86 ? 559 ASN A CB 1 ATOM 4624 C CG . ASN A 1 559 ? 54.970 61.479 -23.984 1.00 6.39 ? 559 ASN A CG 1 ATOM 4625 O OD1 . ASN A 1 559 ? 53.872 61.488 -23.427 1.00 6.70 ? 559 ASN A OD1 1 ATOM 4626 N ND2 . ASN A 1 559 ? 55.327 60.515 -24.868 1.00 7.29 ? 559 ASN A ND2 1 ATOM 4627 N N . THR A 1 560 ? 54.943 62.209 -20.340 1.00 5.50 ? 560 THR A N 1 ATOM 4628 C CA . THR A 1 560 ? 54.976 61.242 -19.242 1.00 5.96 ? 560 THR A CA 1 ATOM 4629 C C . THR A 1 560 ? 54.407 59.868 -19.652 1.00 6.33 ? 560 THR A C 1 ATOM 4630 O O . THR A 1 560 ? 54.609 58.887 -18.919 1.00 7.56 ? 560 THR A O 1 ATOM 4631 C CB . THR A 1 560 ? 54.253 61.865 -18.047 1.00 6.77 ? 560 THR A CB 1 ATOM 4632 O OG1 . THR A 1 560 ? 54.548 61.127 -16.831 1.00 8.80 ? 560 THR A OG1 1 ATOM 4633 C CG2 . THR A 1 560 ? 52.746 61.890 -18.275 1.00 7.21 ? 560 THR A CG2 1 ATOM 4634 N N . LEU A 1 561 ? 53.720 59.787 -20.805 1.00 5.88 ? 561 LEU A N 1 ATOM 4635 C CA . LEU A 1 561 ? 53.100 58.518 -21.229 1.00 6.26 ? 561 LEU A CA 1 ATOM 4636 C C . LEU A 1 561 ? 54.111 57.615 -21.907 1.00 6.90 ? 561 LEU A C 1 ATOM 4637 O O . LEU A 1 561 ? 55.003 58.073 -22.592 1.00 6.68 ? 561 LEU A O 1 ATOM 4638 C CB . LEU A 1 561 ? 51.937 58.776 -22.193 1.00 6.82 ? 561 LEU A CB 1 ATOM 4639 C CG . LEU A 1 561 ? 50.827 59.683 -21.647 1.00 8.00 ? 561 LEU A CG 1 ATOM 4640 C CD1 . LEU A 1 561 ? 49.788 59.863 -22.717 1.00 10.74 ? 561 LEU A CD1 1 ATOM 4641 C CD2 . LEU A 1 561 ? 50.175 59.143 -20.384 1.00 9.70 ? 561 LEU A CD2 1 ATOM 4642 N N . PRO A 1 562 ? 53.978 56.315 -21.738 1.00 6.76 ? 562 PRO A N 1 ATOM 4643 C CA . PRO A 1 562 ? 54.954 55.376 -22.300 1.00 6.93 ? 562 PRO A CA 1 ATOM 4644 C C . PRO A 1 562 ? 54.742 55.009 -23.759 1.00 7.38 ? 562 PRO A C 1 ATOM 4645 O O . PRO A 1 562 ? 54.914 53.878 -24.157 1.00 7.40 ? 562 PRO A O 1 ATOM 4646 C CB . PRO A 1 562 ? 54.801 54.134 -21.378 1.00 7.97 ? 562 PRO A CB 1 ATOM 4647 C CG . PRO A 1 562 ? 53.307 54.138 -21.041 1.00 8.08 ? 562 PRO A CG 1 ATOM 4648 C CD . PRO A 1 562 ? 52.996 55.625 -20.877 1.00 7.43 ? 562 PRO A CD 1 ATOM 4649 N N . HIS A 1 563 ? 54.393 55.984 -24.578 1.00 6.57 ? 563 HIS A N 1 ATOM 4650 C CA . HIS A 1 563 ? 54.358 55.766 -26.016 1.00 7.47 ? 563 HIS A CA 1 ATOM 4651 C C . HIS A 1 563 ? 54.758 57.072 -26.687 1.00 7.35 ? 563 HIS A C 1 ATOM 4652 O O . HIS A 1 563 ? 54.633 58.138 -26.091 1.00 7.31 ? 563 HIS A O 1 ATOM 4653 C CB . HIS A 1 563 ? 52.987 55.291 -26.499 1.00 9.57 ? 563 HIS A CB 1 ATOM 4654 C CG . HIS A 1 563 ? 51.843 56.141 -26.043 1.00 11.25 ? 563 HIS A CG 1 ATOM 4655 N ND1 . HIS A 1 563 ? 51.071 55.809 -24.951 1.00 10.36 ? 563 HIS A ND1 1 ATOM 4656 C CD2 . HIS A 1 563 ? 51.323 57.295 -26.532 1.00 12.51 ? 563 HIS A CD2 1 ATOM 4657 C CE1 . HIS A 1 563 ? 50.113 56.705 -24.793 1.00 11.36 ? 563 HIS A CE1 1 ATOM 4658 N NE2 . HIS A 1 563 ? 50.252 57.633 -25.728 1.00 12.90 ? 563 HIS A NE2 1 ATOM 4659 N N . TRP A 1 564 ? 55.271 56.978 -27.914 1.00 8.15 ? 564 TRP A N 1 ATOM 4660 C CA . TRP A 1 564 ? 55.546 58.180 -28.706 1.00 8.47 ? 564 TRP A CA 1 ATOM 4661 C C . TRP A 1 564 ? 54.285 59.003 -28.836 1.00 8.95 ? 564 TRP A C 1 ATOM 4662 O O . TRP A 1 564 ? 53.175 58.480 -29.016 1.00 9.41 ? 564 TRP A O 1 ATOM 4663 C CB . TRP A 1 564 ? 56.026 57.808 -30.114 1.00 10.04 ? 564 TRP A CB 1 ATOM 4664 C CG . TRP A 1 564 ? 57.460 57.404 -30.146 1.00 9.28 ? 564 TRP A CG 1 ATOM 4665 C CD1 . TRP A 1 564 ? 57.952 56.132 -29.987 1.00 11.04 ? 564 TRP A CD1 1 ATOM 4666 C CD2 . TRP A 1 564 ? 58.602 58.252 -30.310 1.00 10.05 ? 564 TRP A CD2 1 ATOM 4667 N NE1 . TRP A 1 564 ? 59.325 56.141 -30.043 1.00 11.88 ? 564 TRP A NE1 1 ATOM 4668 C CE2 . TRP A 1 564 ? 59.763 57.423 -30.244 1.00 9.71 ? 564 TRP A CE2 1 ATOM 4669 C CE3 . TRP A 1 564 ? 58.777 59.636 -30.503 1.00 10.27 ? 564 TRP A CE3 1 ATOM 4670 C CZ2 . TRP A 1 564 ? 61.067 57.933 -30.356 1.00 11.67 ? 564 TRP A CZ2 1 ATOM 4671 C CZ3 . TRP A 1 564 ? 60.066 60.142 -30.628 1.00 11.26 ? 564 TRP A CZ3 1 ATOM 4672 C CH2 . TRP A 1 564 ? 61.198 59.298 -30.538 1.00 12.32 ? 564 TRP A CH2 1 ATOM 4673 N N . ARG A 1 565 ? 54.434 60.311 -28.645 1.00 9.00 ? 565 ARG A N 1 ATOM 4674 C CA . ARG A 1 565 ? 53.256 61.140 -28.722 1.00 10.28 ? 565 ARG A CA 1 ATOM 4675 C C . ARG A 1 565 ? 53.551 62.385 -29.511 1.00 9.42 ? 565 ARG A C 1 ATOM 4676 O O . ARG A 1 565 ? 54.592 63.008 -29.326 1.00 10.32 ? 565 ARG A O 1 ATOM 4677 C CB . ARG A 1 565 ? 52.752 61.503 -27.318 1.00 10.52 ? 565 ARG A CB 1 ATOM 4678 C CG . ARG A 1 565 ? 51.369 62.175 -27.311 1.00 14.48 ? 565 ARG A CG 1 ATOM 4679 C CD . ARG A 1 565 ? 50.549 61.910 -26.035 1.00 14.64 ? 565 ARG A CD 1 ATOM 4680 N NE . ARG A 1 565 ? 51.314 62.294 -24.857 1.00 15.25 ? 565 ARG A NE 1 ATOM 4681 C CZ . ARG A 1 565 ? 50.787 62.908 -23.792 1.00 10.29 ? 565 ARG A CZ 1 ATOM 4682 N NH1 . ARG A 1 565 ? 49.475 63.260 -23.779 1.00 11.26 ? 565 ARG A NH1 1 ATOM 4683 N NH2 . ARG A 1 565 ? 51.587 63.166 -22.765 1.00 10.12 ? 565 ARG A NH2 1 ATOM 4684 N N . GLU A 1 566 ? 52.620 62.726 -30.397 1.00 11.14 ? 566 GLU A N 1 ATOM 4685 C CA . GLU A 1 566 ? 52.567 64.070 -30.978 1.00 11.88 ? 566 GLU A CA 1 ATOM 4686 C C . GLU A 1 566 ? 51.411 64.859 -30.375 1.00 12.61 ? 566 GLU A C 1 ATOM 4687 O O . GLU A 1 566 ? 50.324 64.324 -30.152 1.00 12.98 ? 566 GLU A O 1 ATOM 4688 C CB . GLU A 1 566 ? 52.341 64.001 -32.479 1.00 14.09 ? 566 GLU A CB 1 ATOM 4689 C CG . GLU A 1 566 ? 53.418 63.260 -33.220 1.00 14.85 ? 566 GLU A CG 1 ATOM 4690 C CD . GLU A 1 566 ? 53.195 63.245 -34.727 1.00 21.95 ? 566 GLU A CD 1 ATOM 4691 O OE1 . GLU A 1 566 ? 52.055 62.985 -35.184 1.00 25.77 ? 566 GLU A OE1 1 ATOM 4692 O OE2 . GLU A 1 566 ? 54.173 63.504 -35.453 1.00 25.83 ? 566 GLU A OE2 1 ATOM 4693 N N . GLN A 1 567 ? 51.633 66.146 -30.150 1.00 10.60 ? 567 GLN A N 1 ATOM 4694 C CA . GLN A 1 567 ? 50.576 67.015 -29.645 1.00 10.64 ? 567 GLN A CA 1 ATOM 4695 C C . GLN A 1 567 ? 50.940 68.416 -30.106 1.00 9.61 ? 567 GLN A C 1 ATOM 4696 O O . GLN A 1 567 ? 52.128 68.780 -30.106 1.00 8.19 ? 567 GLN A O 1 ATOM 4697 C CB . GLN A 1 567 ? 50.558 66.998 -28.119 1.00 10.95 ? 567 GLN A CB 1 ATOM 4698 C CG . GLN A 1 567 ? 49.420 67.787 -27.492 1.00 13.26 ? 567 GLN A CG 1 ATOM 4699 C CD . GLN A 1 567 ? 49.765 68.262 -26.093 1.00 15.34 ? 567 GLN A CD 1 ATOM 4700 O OE1 . GLN A 1 567 ? 49.763 67.472 -25.144 1.00 12.90 ? 567 GLN A OE1 1 ATOM 4701 N NE2 . GLN A 1 567 ? 50.094 69.540 -25.954 1.00 15.91 ? 567 GLN A NE2 1 ATOM 4702 N N . LEU A 1 568 ? 49.942 69.198 -30.509 1.00 9.45 ? 568 LEU A N 1 ATOM 4703 C CA . LEU A 1 568 ? 50.232 70.620 -30.763 1.00 9.40 ? 568 LEU A CA 1 ATOM 4704 C C . LEU A 1 568 ? 50.550 71.287 -29.446 1.00 9.17 ? 568 LEU A C 1 ATOM 4705 O O . LEU A 1 568 ? 49.885 71.042 -28.413 1.00 10.28 ? 568 LEU A O 1 ATOM 4706 C CB . LEU A 1 568 ? 49.065 71.369 -31.406 1.00 11.34 ? 568 LEU A CB 1 ATOM 4707 C CG . LEU A 1 568 ? 48.658 70.946 -32.810 1.00 13.41 ? 568 LEU A CG 1 ATOM 4708 C CD1 . LEU A 1 568 ? 47.677 71.958 -33.339 1.00 14.58 ? 568 LEU A CD1 1 ATOM 4709 C CD2 . LEU A 1 568 ? 49.849 70.968 -33.720 1.00 14.81 ? 568 LEU A CD2 1 ATOM 4710 N N . VAL A 1 569 ? 51.569 72.115 -29.459 1.00 7.15 ? 569 VAL A N 1 ATOM 4711 C CA . VAL A 1 569 ? 51.927 72.945 -28.323 1.00 7.58 ? 569 VAL A CA 1 ATOM 4712 C C . VAL A 1 569 ? 51.985 74.399 -28.736 1.00 8.86 ? 569 VAL A C 1 ATOM 4713 O O . VAL A 1 569 ? 52.236 74.698 -29.900 1.00 8.81 ? 569 VAL A O 1 ATOM 4714 C CB . VAL A 1 569 ? 53.293 72.538 -27.737 1.00 8.25 ? 569 VAL A CB 1 ATOM 4715 C CG1 . VAL A 1 569 ? 53.225 71.124 -27.085 1.00 8.94 ? 569 VAL A CG1 1 ATOM 4716 C CG2 . VAL A 1 569 ? 54.403 72.626 -28.804 1.00 8.95 ? 569 VAL A CG2 1 ATOM 4717 N N . ASP A 1 570 ? 51.726 75.292 -27.790 1.00 8.63 ? 570 ASP A N 1 ATOM 4718 C CA . ASP A 1 570 ? 51.775 76.714 -28.112 1.00 10.03 ? 570 ASP A CA 1 ATOM 4719 C C . ASP A 1 570 ? 52.577 77.479 -27.090 1.00 10.32 ? 570 ASP A C 1 ATOM 4720 O O . ASP A 1 570 ? 52.687 77.103 -25.911 1.00 11.26 ? 570 ASP A O 1 ATOM 4721 C CB . ASP A 1 570 ? 50.371 77.294 -28.255 1.00 11.16 ? 570 ASP A CB 1 ATOM 4722 C CG . ASP A 1 570 ? 49.675 77.481 -26.928 1.00 17.08 ? 570 ASP A CG 1 ATOM 4723 O OD1 . ASP A 1 570 ? 49.550 76.488 -26.190 1.00 22.13 ? 570 ASP A OD1 1 ATOM 4724 O OD2 . ASP A 1 570 ? 49.209 78.578 -26.545 1.00 22.78 ? 570 ASP A OD2 1 ATOM 4725 N N . PHE A 1 571 ? 53.176 78.562 -27.570 1.00 7.83 ? 571 PHE A N 1 ATOM 4726 C CA . PHE A 1 571 ? 53.949 79.457 -26.723 1.00 8.30 ? 571 PHE A CA 1 ATOM 4727 C C . PHE A 1 571 ? 53.565 80.894 -27.104 1.00 8.79 ? 571 PHE A C 1 ATOM 4728 O O . PHE A 1 571 ? 53.194 81.162 -28.247 1.00 9.75 ? 571 PHE A O 1 ATOM 4729 C CB . PHE A 1 571 ? 55.451 79.269 -26.973 1.00 9.17 ? 571 PHE A CB 1 ATOM 4730 C CG . PHE A 1 571 ? 55.973 77.934 -26.529 1.00 7.50 ? 571 PHE A CG 1 ATOM 4731 C CD1 . PHE A 1 571 ? 55.963 76.833 -27.396 1.00 8.52 ? 571 PHE A CD1 1 ATOM 4732 C CD2 . PHE A 1 571 ? 56.436 77.754 -25.239 1.00 8.50 ? 571 PHE A CD2 1 ATOM 4733 C CE1 . PHE A 1 571 ? 56.397 75.577 -26.955 1.00 8.57 ? 571 PHE A CE1 1 ATOM 4734 C CE2 . PHE A 1 571 ? 56.865 76.504 -24.807 1.00 8.35 ? 571 PHE A CE2 1 ATOM 4735 C CZ . PHE A 1 571 ? 56.847 75.431 -25.678 1.00 9.78 ? 571 PHE A CZ 1 ATOM 4736 N N . TYR A 1 572 ? 53.682 81.807 -26.163 1.00 8.31 ? 572 TYR A N 1 ATOM 4737 C CA . TYR A 1 572 ? 53.581 83.237 -26.486 1.00 9.56 ? 572 TYR A CA 1 ATOM 4738 C C . TYR A 1 572 ? 54.959 83.750 -26.860 1.00 9.19 ? 572 TYR A C 1 ATOM 4739 O O . TYR A 1 572 ? 55.953 83.430 -26.195 1.00 9.17 ? 572 TYR A O 1 ATOM 4740 C CB . TYR A 1 572 ? 53.104 84.029 -25.268 1.00 10.90 ? 572 TYR A CB 1 ATOM 4741 C CG . TYR A 1 572 ? 51.619 83.920 -24.941 1.00 13.26 ? 572 TYR A CG 1 ATOM 4742 C CD1 . TYR A 1 572 ? 50.778 83.049 -25.632 1.00 14.02 ? 572 TYR A CD1 1 ATOM 4743 C CD2 . TYR A 1 572 ? 51.073 84.678 -23.911 1.00 18.48 ? 572 TYR A CD2 1 ATOM 4744 C CE1 . TYR A 1 572 ? 49.405 82.960 -25.316 1.00 16.35 ? 572 TYR A CE1 1 ATOM 4745 C CE2 . TYR A 1 572 ? 49.719 84.590 -23.587 1.00 18.75 ? 572 TYR A CE2 1 ATOM 4746 C CZ . TYR A 1 572 ? 48.906 83.741 -24.293 1.00 17.70 ? 572 TYR A CZ 1 ATOM 4747 O OH . TYR A 1 572 ? 47.560 83.658 -23.974 1.00 20.50 ? 572 TYR A OH 1 ATOM 4748 N N . VAL A 1 573 ? 55.003 84.545 -27.934 1.00 8.96 ? 573 VAL A N 1 ATOM 4749 C CA . VAL A 1 573 ? 56.263 85.098 -28.443 1.00 10.04 ? 573 VAL A CA 1 ATOM 4750 C C . VAL A 1 573 ? 56.054 86.583 -28.740 1.00 9.35 ? 573 VAL A C 1 ATOM 4751 O O . VAL A 1 573 ? 54.931 87.025 -28.992 1.00 9.74 ? 573 VAL A O 1 ATOM 4752 C CB . VAL A 1 573 ? 56.715 84.357 -29.730 1.00 10.28 ? 573 VAL A CB 1 ATOM 4753 C CG1 . VAL A 1 573 ? 57.308 82.988 -29.405 1.00 11.81 ? 573 VAL A CG1 1 ATOM 4754 C CG2 . VAL A 1 573 ? 55.571 84.220 -30.719 1.00 10.56 ? 573 VAL A CG2 1 ATOM 4755 N N . SER A 1 574 ? 57.142 87.331 -28.720 1.00 9.34 ? 574 SER A N 1 ATOM 4756 C CA . SER A 1 574 ? 57.024 88.786 -28.886 1.00 10.64 ? 574 SER A CA 1 ATOM 4757 C C . SER A 1 574 ? 57.058 89.282 -30.336 1.00 11.99 ? 574 SER A C 1 ATOM 4758 O O . SER A 1 574 ? 57.054 90.505 -30.570 1.00 14.89 ? 574 SER A O 1 ATOM 4759 C CB . SER A 1 574 ? 58.120 89.477 -28.090 1.00 10.55 ? 574 SER A CB 1 ATOM 4760 O OG . SER A 1 574 ? 59.370 89.086 -28.600 1.00 12.24 ? 574 SER A OG 1 ATOM 4761 N N . SER A 1 575 ? 57.066 88.370 -31.310 1.00 12.05 ? 575 SER A N 1 ATOM 4762 C CA . SER A 1 575 ? 57.004 88.707 -32.738 1.00 13.29 ? 575 SER A CA 1 ATOM 4763 C C . SER A 1 575 ? 56.166 87.672 -33.443 1.00 13.23 ? 575 SER A C 1 ATOM 4764 O O . SER A 1 575 ? 56.151 86.511 -33.048 1.00 12.84 ? 575 SER A O 1 ATOM 4765 C CB . SER A 1 575 ? 58.401 88.676 -33.354 1.00 14.45 ? 575 SER A CB 1 ATOM 4766 O OG . SER A 1 575 ? 58.393 88.769 -34.780 1.00 14.91 ? 575 SER A OG 1 ATOM 4767 N N . PRO A 1 576 ? 55.472 88.049 -34.503 1.00 12.69 ? 576 PRO A N 1 ATOM 4768 C CA . PRO A 1 576 ? 54.793 87.038 -35.306 1.00 12.27 ? 576 PRO A CA 1 ATOM 4769 C C . PRO A 1 576 ? 55.724 86.315 -36.285 1.00 12.12 ? 576 PRO A C 1 ATOM 4770 O O . PRO A 1 576 ? 55.320 85.352 -36.920 1.00 12.82 ? 576 PRO A O 1 ATOM 4771 C CB . PRO A 1 576 ? 53.731 87.835 -36.064 1.00 13.50 ? 576 PRO A CB 1 ATOM 4772 C CG . PRO A 1 576 ? 54.266 89.229 -36.129 1.00 15.25 ? 576 PRO A CG 1 ATOM 4773 C CD . PRO A 1 576 ? 55.240 89.418 -35.013 1.00 13.02 ? 576 PRO A CD 1 ATOM 4774 N N . PHE A 1 577 ? 56.952 86.802 -36.435 1.00 11.82 ? 577 PHE A N 1 ATOM 4775 C CA . PHE A 1 577 ? 57.837 86.264 -37.462 1.00 11.81 ? 577 PHE A CA 1 ATOM 4776 C C . PHE A 1 577 ? 58.791 85.323 -36.796 1.00 12.15 ? 577 PHE A C 1 ATOM 4777 O O . PHE A 1 577 ? 59.948 85.638 -36.544 1.00 11.61 ? 577 PHE A O 1 ATOM 4778 C CB . PHE A 1 577 ? 58.575 87.403 -38.168 1.00 12.90 ? 577 PHE A CB 1 ATOM 4779 C CG . PHE A 1 577 ? 57.647 88.425 -38.780 1.00 16.35 ? 577 PHE A CG 1 ATOM 4780 C CD1 . PHE A 1 577 ? 56.580 88.035 -39.570 1.00 17.95 ? 577 PHE A CD1 1 ATOM 4781 C CD2 . PHE A 1 577 ? 57.857 89.787 -38.552 1.00 18.84 ? 577 PHE A CD2 1 ATOM 4782 C CE1 . PHE A 1 577 ? 55.728 88.990 -40.153 1.00 19.53 ? 577 PHE A CE1 1 ATOM 4783 C CE2 . PHE A 1 577 ? 57.010 90.740 -39.120 1.00 21.83 ? 577 PHE A CE2 1 ATOM 4784 C CZ . PHE A 1 577 ? 55.952 90.330 -39.920 1.00 20.20 ? 577 PHE A CZ 1 ATOM 4785 N N . VAL A 1 578 ? 58.249 84.154 -36.453 1.00 11.40 ? 578 VAL A N 1 ATOM 4786 C CA . VAL A 1 578 ? 59.011 83.170 -35.700 1.00 11.30 ? 578 VAL A CA 1 ATOM 4787 C C . VAL A 1 578 ? 58.919 81.835 -36.416 1.00 11.10 ? 578 VAL A C 1 ATOM 4788 O O . VAL A 1 578 ? 57.864 81.476 -36.891 1.00 11.43 ? 578 VAL A O 1 ATOM 4789 C CB . VAL A 1 578 ? 58.489 83.064 -34.239 1.00 11.65 ? 578 VAL A CB 1 ATOM 4790 C CG1 . VAL A 1 578 ? 59.178 81.901 -33.462 1.00 11.61 ? 578 VAL A CG1 1 ATOM 4791 C CG2 . VAL A 1 578 ? 58.704 84.374 -33.519 1.00 12.44 ? 578 VAL A CG2 1 ATOM 4792 N N . SER A 1 579 ? 60.044 81.139 -36.512 1.00 11.87 ? 579 SER A N 1 ATOM 4793 C CA . SER A 1 579 ? 60.023 79.822 -37.110 1.00 12.56 ? 579 SER A CA 1 ATOM 4794 C C . SER A 1 579 ? 60.541 78.817 -36.090 1.00 10.33 ? 579 SER A C 1 ATOM 4795 O O . SER A 1 579 ? 61.286 79.165 -35.178 1.00 10.25 ? 579 SER A O 1 ATOM 4796 C CB . SER A 1 579 ? 60.849 79.788 -38.384 1.00 15.62 ? 579 SER A CB 1 ATOM 4797 O OG . SER A 1 579 ? 62.127 80.260 -38.108 1.00 21.03 ? 579 SER A OG 1 ATOM 4798 N N . VAL A 1 580 ? 60.166 77.570 -36.308 1.00 8.86 ? 580 VAL A N 1 ATOM 4799 C CA . VAL A 1 580 ? 60.482 76.470 -35.389 1.00 9.40 ? 580 VAL A CA 1 ATOM 4800 C C . VAL A 1 580 ? 61.360 75.452 -36.089 1.00 10.08 ? 580 VAL A C 1 ATOM 4801 O O . VAL A 1 580 ? 61.123 75.116 -37.246 1.00 10.78 ? 580 VAL A O 1 ATOM 4802 C CB . VAL A 1 580 ? 59.189 75.787 -34.916 1.00 9.26 ? 580 VAL A CB 1 ATOM 4803 C CG1 . VAL A 1 580 ? 59.495 74.695 -33.876 1.00 10.59 ? 580 VAL A CG1 1 ATOM 4804 C CG2 . VAL A 1 580 ? 58.217 76.828 -34.309 1.00 10.94 ? 580 VAL A CG2 1 ATOM 4805 N N . THR A 1 581 ? 62.345 74.964 -35.357 1.00 10.55 ? 581 THR A N 1 ATOM 4806 C CA . THR A 1 581 ? 63.204 73.883 -35.833 1.00 10.60 ? 581 THR A CA 1 ATOM 4807 C C . THR A 1 581 ? 63.342 72.869 -34.707 1.00 11.32 ? 581 THR A C 1 ATOM 4808 O O . THR A 1 581 ? 63.233 73.204 -33.516 1.00 10.39 ? 581 THR A O 1 ATOM 4809 C CB . THR A 1 581 ? 64.624 74.357 -36.228 1.00 10.83 ? 581 THR A CB 1 ATOM 4810 O OG1 . THR A 1 581 ? 65.126 75.294 -35.268 1.00 13.13 ? 581 THR A OG1 1 ATOM 4811 C CG2 . THR A 1 581 ? 64.593 75.170 -37.536 1.00 12.42 ? 581 THR A CG2 1 ATOM 4812 N N . ASP A 1 582 ? 63.603 71.630 -35.082 1.00 12.09 ? 582 ASP A N 1 ATOM 4813 C CA . ASP A 1 582 ? 63.970 70.585 -34.134 1.00 14.31 ? 582 ASP A CA 1 ATOM 4814 C C . ASP A 1 582 ? 65.461 70.614 -33.841 1.00 15.84 ? 582 ASP A C 1 ATOM 4815 O O . ASP A 1 582 ? 66.150 71.473 -34.315 1.00 14.56 ? 582 ASP A O 1 ATOM 4816 C CB . ASP A 1 582 ? 63.454 69.225 -34.604 1.00 15.98 ? 582 ASP A CB 1 ATOM 4817 C CG . ASP A 1 582 ? 64.192 68.679 -35.819 1.00 17.42 ? 582 ASP A CG 1 ATOM 4818 O OD1 . ASP A 1 582 ? 65.282 69.160 -36.132 1.00 16.74 ? 582 ASP A OD1 1 ATOM 4819 O OD2 . ASP A 1 582 ? 63.663 67.719 -36.396 1.00 21.89 ? 582 ASP A OD2 1 ATOM 4820 N N . LEU A 1 583 ? 65.980 69.711 -33.025 1.00 18.55 ? 583 LEU A N 1 ATOM 4821 C CA . LEU A 1 583 ? 67.405 69.866 -32.790 1.00 20.46 ? 583 LEU A CA 1 ATOM 4822 C C . LEU A 1 583 ? 68.311 69.133 -33.771 1.00 19.87 ? 583 LEU A C 1 ATOM 4823 O O . LEU A 1 583 ? 69.450 68.938 -33.475 1.00 21.65 ? 583 LEU A O 1 ATOM 4824 C CB . LEU A 1 583 ? 67.857 69.711 -31.315 1.00 20.93 ? 583 LEU A CB 1 ATOM 4825 C CG . LEU A 1 583 ? 68.734 70.817 -30.683 1.00 21.50 ? 583 LEU A CG 1 ATOM 4826 C CD1 . LEU A 1 583 ? 67.971 72.130 -30.637 1.00 24.73 ? 583 LEU A CD1 1 ATOM 4827 C CD2 . LEU A 1 583 ? 69.227 70.475 -29.264 1.00 21.46 ? 583 LEU A CD2 1 ATOM 4828 N N . ALA A 1 584 ? 67.802 68.813 -34.957 1.00 18.17 ? 584 ALA A N 1 ATOM 4829 C CA . ALA A 1 584 ? 68.667 68.610 -36.127 1.00 15.77 ? 584 ALA A CA 1 ATOM 4830 C C . ALA A 1 584 ? 68.516 69.748 -37.121 1.00 14.51 ? 584 ALA A C 1 ATOM 4831 O O . ALA A 1 584 ? 68.934 69.655 -38.247 1.00 13.87 ? 584 ALA A O 1 ATOM 4832 C CB . ALA A 1 584 ? 68.348 67.307 -36.790 1.00 16.77 ? 584 ALA A CB 1 ATOM 4833 N N A ASN A 1 585 ? 67.889 70.807 -36.641 0.50 13.47 ? 585 ASN A N 1 ATOM 4834 N N B ASN A 1 585 ? 67.938 70.861 -36.691 0.50 14.07 ? 585 ASN A N 1 ATOM 4835 C CA A ASN A 1 585 ? 67.674 72.008 -37.413 0.50 13.58 ? 585 ASN A CA 1 ATOM 4836 C CA B ASN A 1 585 ? 67.764 72.025 -37.576 0.50 14.69 ? 585 ASN A CA 1 ATOM 4837 C C A ASN A 1 585 ? 66.804 71.755 -38.638 0.50 13.62 ? 585 ASN A C 1 ATOM 4838 C C B ASN A 1 585 ? 66.689 71.832 -38.645 0.50 14.42 ? 585 ASN A C 1 ATOM 4839 O O A ASN A 1 585 ? 66.947 72.443 -39.646 0.50 14.77 ? 585 ASN A O 1 ATOM 4840 O O B ASN A 1 585 ? 66.551 72.650 -39.563 0.50 15.39 ? 585 ASN A O 1 ATOM 4841 C CB A ASN A 1 585 ? 69.014 72.657 -37.787 0.50 13.73 ? 585 ASN A CB 1 ATOM 4842 C CB B ASN A 1 585 ? 69.085 72.416 -38.264 0.50 15.53 ? 585 ASN A CB 1 ATOM 4843 C CG A ASN A 1 585 ? 68.852 74.060 -38.305 0.50 13.81 ? 585 ASN A CG 1 ATOM 4844 C CG B ASN A 1 585 ? 69.718 73.665 -37.681 0.50 17.28 ? 585 ASN A CG 1 ATOM 4845 O OD1 A ASN A 1 585 ? 68.055 74.849 -37.771 0.50 14.13 ? 585 ASN A OD1 1 ATOM 4846 O OD1 B ASN A 1 585 ? 69.074 74.718 -37.556 0.50 20.48 ? 585 ASN A OD1 1 ATOM 4847 N ND2 A ASN A 1 585 ? 69.609 74.396 -39.348 0.50 14.14 ? 585 ASN A ND2 1 ATOM 4848 N ND2 B ASN A 1 585 ? 71.000 73.567 -37.349 0.50 20.53 ? 585 ASN A ND2 1 ATOM 4849 N N . ASN A 1 586 ? 65.918 70.761 -38.527 1.00 13.49 ? 586 ASN A N 1 ATOM 4850 C CA . ASN A 1 586 ? 64.853 70.488 -39.491 1.00 13.77 ? 586 ASN A CA 1 ATOM 4851 C C . ASN A 1 586 ? 63.727 71.497 -39.233 1.00 14.51 ? 586 ASN A C 1 ATOM 4852 O O . ASN A 1 586 ? 63.299 71.665 -38.081 1.00 12.99 ? 586 ASN A O 1 ATOM 4853 C CB . ASN A 1 586 ? 64.271 69.091 -39.278 1.00 15.02 ? 586 ASN A CB 1 ATOM 4854 C CG . ASN A 1 586 ? 65.289 67.980 -39.473 1.00 15.90 ? 586 ASN A CG 1 ATOM 4855 O OD1 . ASN A 1 586 ? 66.135 68.041 -40.380 1.00 17.02 ? 586 ASN A OD1 1 ATOM 4856 N ND2 . ASN A 1 586 ? 65.196 66.947 -38.639 1.00 17.43 ? 586 ASN A ND2 1 ATOM 4857 N N . PRO A 1 587 ? 63.251 72.206 -40.249 1.00 13.44 ? 587 PRO A N 1 ATOM 4858 C CA . PRO A 1 587 ? 62.069 73.056 -40.072 1.00 13.69 ? 587 PRO A CA 1 ATOM 4859 C C . PRO A 1 587 ? 60.863 72.264 -39.590 1.00 12.72 ? 587 PRO A C 1 ATOM 4860 O O . PRO A 1 587 ? 60.630 71.109 -39.957 1.00 13.48 ? 587 PRO A O 1 ATOM 4861 C CB . PRO A 1 587 ? 61.786 73.616 -41.472 1.00 14.12 ? 587 PRO A CB 1 ATOM 4862 C CG . PRO A 1 587 ? 62.874 73.134 -42.375 1.00 15.54 ? 587 PRO A CG 1 ATOM 4863 C CD . PRO A 1 587 ? 63.849 72.313 -41.602 1.00 14.69 ? 587 PRO A CD 1 ATOM 4864 N N . VAL A 1 588 ? 60.076 72.912 -38.729 1.00 11.82 ? 588 VAL A N 1 ATOM 4865 C CA . VAL A 1 588 ? 58.844 72.330 -38.244 1.00 11.19 ? 588 VAL A CA 1 ATOM 4866 C C . VAL A 1 588 ? 57.718 73.301 -38.632 1.00 10.01 ? 588 VAL A C 1 ATOM 4867 O O . VAL A 1 588 ? 57.822 74.522 -38.372 1.00 11.30 ? 588 VAL A O 1 ATOM 4868 C CB . VAL A 1 588 ? 58.881 72.156 -36.708 1.00 12.42 ? 588 VAL A CB 1 ATOM 4869 C CG1 . VAL A 1 588 ? 57.548 71.704 -36.177 1.00 12.48 ? 588 VAL A CG1 1 ATOM 4870 C CG2 . VAL A 1 588 ? 59.996 71.174 -36.303 1.00 12.77 ? 588 VAL A CG2 1 ATOM 4871 N N . GLU A 1 589 ? 56.659 72.775 -39.234 1.00 9.95 ? 589 GLU A N 1 ATOM 4872 C CA . GLU A 1 589 ? 55.527 73.596 -39.656 1.00 11.34 ? 589 GLU A CA 1 ATOM 4873 C C . GLU A 1 589 ? 54.888 74.257 -38.429 1.00 11.05 ? 589 GLU A C 1 ATOM 4874 O O . GLU A 1 589 ? 54.705 73.613 -37.383 1.00 11.08 ? 589 GLU A O 1 ATOM 4875 C CB . GLU A 1 589 ? 54.491 72.747 -40.381 1.00 12.93 ? 589 GLU A CB 1 ATOM 4876 C CG . GLU A 1 589 ? 53.308 73.572 -40.831 1.00 18.08 ? 589 GLU A CG 1 ATOM 4877 C CD . GLU A 1 589 ? 52.335 72.847 -41.723 1.00 25.17 ? 589 GLU A CD 1 ATOM 4878 O OE1 . GLU A 1 589 ? 52.600 71.674 -42.084 1.00 28.63 ? 589 GLU A OE1 1 ATOM 4879 O OE2 . GLU A 1 589 ? 51.302 73.473 -42.076 1.00 28.58 ? 589 GLU A OE2 1 ATOM 4880 N N . ALA A 1 590 ? 54.559 75.530 -38.523 1.00 9.89 ? 590 ALA A N 1 ATOM 4881 C CA . ALA A 1 590 ? 54.051 76.263 -37.362 1.00 9.54 ? 590 ALA A CA 1 ATOM 4882 C C . ALA A 1 590 ? 52.953 77.183 -37.797 1.00 9.81 ? 590 ALA A C 1 ATOM 4883 O O . ALA A 1 590 ? 52.843 77.521 -38.995 1.00 9.99 ? 590 ALA A O 1 ATOM 4884 C CB . ALA A 1 590 ? 55.118 77.029 -36.681 1.00 10.56 ? 590 ALA A CB 1 ATOM 4885 N N . GLN A 1 591 ? 52.124 77.580 -36.849 1.00 8.34 ? 591 GLN A N 1 ATOM 4886 C CA . GLN A 1 591 ? 51.056 78.518 -37.137 1.00 7.95 ? 591 GLN A CA 1 ATOM 4887 C C . GLN A 1 591 ? 51.106 79.598 -36.095 1.00 8.22 ? 591 GLN A C 1 ATOM 4888 O O . GLN A 1 591 ? 51.270 79.320 -34.906 1.00 10.02 ? 591 GLN A O 1 ATOM 4889 C CB . GLN A 1 591 ? 49.696 77.825 -37.102 1.00 8.33 ? 591 GLN A CB 1 ATOM 4890 C CG . GLN A 1 591 ? 48.496 78.815 -37.049 1.00 8.31 ? 591 GLN A CG 1 ATOM 4891 C CD . GLN A 1 591 ? 47.167 78.091 -36.845 1.00 8.65 ? 591 GLN A CD 1 ATOM 4892 O OE1 . GLN A 1 591 ? 46.936 77.036 -37.475 1.00 9.76 ? 591 GLN A OE1 1 ATOM 4893 N NE2 . GLN A 1 591 ? 46.294 78.637 -36.023 1.00 10.20 ? 591 GLN A NE2 1 ATOM 4894 N N . VAL A 1 592 ? 51.012 80.861 -36.528 1.00 9.14 ? 592 VAL A N 1 ATOM 4895 C CA . VAL A 1 592 ? 50.944 81.960 -35.573 1.00 8.30 ? 592 VAL A CA 1 ATOM 4896 C C . VAL A 1 592 ? 49.539 82.531 -35.560 1.00 9.16 ? 592 VAL A C 1 ATOM 4897 O O . VAL A 1 592 ? 48.922 82.640 -36.608 1.00 9.90 ? 592 VAL A O 1 ATOM 4898 C CB . VAL A 1 592 ? 51.976 83.043 -35.909 1.00 8.88 ? 592 VAL A CB 1 ATOM 4899 C CG1 . VAL A 1 592 ? 51.746 84.303 -35.063 1.00 9.35 ? 592 VAL A CG1 1 ATOM 4900 C CG2 . VAL A 1 592 ? 53.370 82.498 -35.624 1.00 9.28 ? 592 VAL A CG2 1 ATOM 4901 N N . SER A 1 593 ? 49.039 82.827 -34.361 1.00 9.64 ? 593 SER A N 1 ATOM 4902 C CA . SER A 1 593 ? 47.697 83.365 -34.171 1.00 10.02 ? 593 SER A CA 1 ATOM 4903 C C . SER A 1 593 ? 47.840 84.536 -33.211 1.00 10.47 ? 593 SER A C 1 ATOM 4904 O O . SER A 1 593 ? 48.825 84.632 -32.457 1.00 11.18 ? 593 SER A O 1 ATOM 4905 C CB . SER A 1 593 ? 46.734 82.324 -33.519 1.00 10.80 ? 593 SER A CB 1 ATOM 4906 O OG . SER A 1 593 ? 46.518 81.162 -34.320 1.00 13.98 ? 593 SER A OG 1 ATOM 4907 N N . PRO A 1 594 ? 46.862 85.423 -33.165 1.00 10.60 ? 594 PRO A N 1 ATOM 4908 C CA . PRO A 1 594 ? 46.918 86.482 -32.165 1.00 10.46 ? 594 PRO A CA 1 ATOM 4909 C C . PRO A 1 594 ? 46.704 85.951 -30.742 1.00 10.54 ? 594 PRO A C 1 ATOM 4910 O O . PRO A 1 594 ? 46.278 84.794 -30.538 1.00 10.74 ? 594 PRO A O 1 ATOM 4911 C CB . PRO A 1 594 ? 45.763 87.419 -32.568 1.00 10.85 ? 594 PRO A CB 1 ATOM 4912 C CG . PRO A 1 594 ? 45.344 86.967 -33.981 1.00 11.12 ? 594 PRO A CG 1 ATOM 4913 C CD . PRO A 1 594 ? 45.629 85.500 -33.966 1.00 9.89 ? 594 PRO A CD 1 ATOM 4914 N N . VAL A 1 595 ? 47.019 86.798 -29.752 1.00 10.47 ? 595 VAL A N 1 ATOM 4915 C CA . VAL A 1 595 ? 46.651 86.525 -28.377 1.00 11.50 ? 595 VAL A CA 1 ATOM 4916 C C . VAL A 1 595 ? 45.384 87.325 -28.111 1.00 12.21 ? 595 VAL A C 1 ATOM 4917 O O . VAL A 1 595 ? 45.385 88.566 -28.146 1.00 12.87 ? 595 VAL A O 1 ATOM 4918 C CB . VAL A 1 595 ? 47.768 86.903 -27.410 1.00 11.96 ? 595 VAL A CB 1 ATOM 4919 C CG1 . VAL A 1 595 ? 47.300 86.729 -25.984 1.00 12.82 ? 595 VAL A CG1 1 ATOM 4920 C CG2 . VAL A 1 595 ? 48.977 86.036 -27.674 1.00 11.27 ? 595 VAL A CG2 1 ATOM 4921 N N . TRP A 1 596 ? 44.296 86.602 -27.942 1.00 11.67 ? 596 TRP A N 1 ATOM 4922 C CA . TRP A 1 596 ? 42.988 87.170 -27.709 1.00 12.89 ? 596 TRP A CA 1 ATOM 4923 C C . TRP A 1 596 ? 42.600 87.038 -26.254 1.00 14.63 ? 596 TRP A C 1 ATOM 4924 O O . TRP A 1 596 ? 42.702 85.953 -25.672 1.00 15.47 ? 596 TRP A O 1 ATOM 4925 C CB . TRP A 1 596 ? 41.938 86.418 -28.556 1.00 12.07 ? 596 TRP A CB 1 ATOM 4926 C CG . TRP A 1 596 ? 42.074 86.600 -30.028 1.00 11.87 ? 596 TRP A CG 1 ATOM 4927 C CD1 . TRP A 1 596 ? 42.461 85.656 -30.959 1.00 10.05 ? 596 TRP A CD1 1 ATOM 4928 C CD2 . TRP A 1 596 ? 41.746 87.776 -30.768 1.00 10.97 ? 596 TRP A CD2 1 ATOM 4929 N NE1 . TRP A 1 596 ? 42.415 86.202 -32.220 1.00 11.45 ? 596 TRP A NE1 1 ATOM 4930 C CE2 . TRP A 1 596 ? 41.982 87.499 -32.130 1.00 11.23 ? 596 TRP A CE2 1 ATOM 4931 C CE3 . TRP A 1 596 ? 41.281 89.057 -30.414 1.00 10.27 ? 596 TRP A CE3 1 ATOM 4932 C CZ2 . TRP A 1 596 ? 41.777 88.449 -33.134 1.00 12.18 ? 596 TRP A CZ2 1 ATOM 4933 C CZ3 . TRP A 1 596 ? 41.080 90.005 -31.417 1.00 11.73 ? 596 TRP A CZ3 1 ATOM 4934 C CH2 . TRP A 1 596 ? 41.322 89.683 -32.751 1.00 12.10 ? 596 TRP A CH2 1 ATOM 4935 N N . SER A 1 597 ? 42.165 88.141 -25.666 1.00 15.23 ? 597 SER A N 1 ATOM 4936 C CA A SER A 1 597 ? 41.615 88.079 -24.322 0.50 15.48 ? 597 SER A CA 1 ATOM 4937 C CA B SER A 1 597 ? 41.669 88.177 -24.296 0.50 16.06 ? 597 SER A CA 1 ATOM 4938 C C . SER A 1 597 ? 40.229 88.689 -24.331 1.00 15.80 ? 597 SER A C 1 ATOM 4939 O O . SER A 1 597 ? 39.920 89.575 -25.129 1.00 17.08 ? 597 SER A O 1 ATOM 4940 C CB A SER A 1 597 ? 42.499 88.807 -23.324 0.50 16.19 ? 597 SER A CB 1 ATOM 4941 C CB B SER A 1 597 ? 42.540 89.114 -23.449 0.50 16.81 ? 597 SER A CB 1 ATOM 4942 O OG A SER A 1 597 ? 42.686 90.129 -23.769 0.50 14.33 ? 597 SER A OG 1 ATOM 4943 O OG B SER A 1 597 ? 43.922 88.853 -23.654 0.50 18.47 ? 597 SER A OG 1 ATOM 4944 N N . TRP A 1 598 ? 39.388 88.157 -23.463 1.00 14.97 ? 598 TRP A N 1 ATOM 4945 C CA . TRP A 1 598 ? 37.999 88.568 -23.436 1.00 14.78 ? 598 TRP A CA 1 ATOM 4946 C C . TRP A 1 598 ? 37.770 89.473 -22.250 1.00 16.19 ? 598 TRP A C 1 ATOM 4947 O O . TRP A 1 598 ? 38.333 89.255 -21.189 1.00 17.01 ? 598 TRP A O 1 ATOM 4948 C CB . TRP A 1 598 ? 37.102 87.340 -23.350 1.00 13.91 ? 598 TRP A CB 1 ATOM 4949 C CG . TRP A 1 598 ? 37.024 86.608 -24.659 1.00 11.86 ? 598 TRP A CG 1 ATOM 4950 C CD1 . TRP A 1 598 ? 37.946 85.715 -25.159 1.00 11.41 ? 598 TRP A CD1 1 ATOM 4951 C CD2 . TRP A 1 598 ? 35.992 86.710 -25.634 1.00 11.38 ? 598 TRP A CD2 1 ATOM 4952 N NE1 . TRP A 1 598 ? 37.537 85.260 -26.393 1.00 11.45 ? 598 TRP A NE1 1 ATOM 4953 C CE2 . TRP A 1 598 ? 36.335 85.839 -26.702 1.00 8.82 ? 598 TRP A CE2 1 ATOM 4954 C CE3 . TRP A 1 598 ? 34.795 87.431 -25.722 1.00 9.18 ? 598 TRP A CE3 1 ATOM 4955 C CZ2 . TRP A 1 598 ? 35.529 85.682 -27.845 1.00 10.94 ? 598 TRP A CZ2 1 ATOM 4956 C CZ3 . TRP A 1 598 ? 33.982 87.260 -26.854 1.00 10.11 ? 598 TRP A CZ3 1 ATOM 4957 C CH2 . TRP A 1 598 ? 34.358 86.388 -27.895 1.00 10.78 ? 598 TRP A CH2 1 ATOM 4958 N N . HIS A 1 599 ? 36.924 90.468 -22.459 1.00 18.15 ? 599 HIS A N 1 ATOM 4959 C CA . HIS A 1 599 ? 36.711 91.514 -21.480 1.00 20.84 ? 599 HIS A CA 1 ATOM 4960 C C . HIS A 1 599 ? 35.250 91.802 -21.365 1.00 21.14 ? 599 HIS A C 1 ATOM 4961 O O . HIS A 1 599 ? 34.545 91.888 -22.377 1.00 20.44 ? 599 HIS A O 1 ATOM 4962 C CB . HIS A 1 599 ? 37.451 92.780 -21.913 1.00 22.05 ? 599 HIS A CB 1 ATOM 4963 C CG . HIS A 1 599 ? 38.942 92.613 -21.945 1.00 26.43 ? 599 HIS A CG 1 ATOM 4964 N ND1 . HIS A 1 599 ? 39.662 92.156 -20.858 1.00 29.36 ? 599 HIS A ND1 1 ATOM 4965 C CD2 . HIS A 1 599 ? 39.842 92.816 -22.936 1.00 30.54 ? 599 HIS A CD2 1 ATOM 4966 C CE1 . HIS A 1 599 ? 40.944 92.092 -21.177 1.00 31.10 ? 599 HIS A CE1 1 ATOM 4967 N NE2 . HIS A 1 599 ? 41.080 92.486 -22.433 1.00 30.74 ? 599 HIS A NE2 1 ATOM 4968 N N . HIS A 1 600 ? 34.802 91.942 -20.125 1.00 22.80 ? 600 HIS A N 1 ATOM 4969 C CA . HIS A 1 600 ? 33.464 92.450 -19.882 1.00 24.49 ? 600 HIS A CA 1 ATOM 4970 C C . HIS A 1 600 ? 33.628 93.943 -19.891 1.00 24.69 ? 600 HIS A C 1 ATOM 4971 O O . HIS A 1 600 ? 34.261 94.541 -18.998 1.00 25.39 ? 600 HIS A O 1 ATOM 4972 C CB . HIS A 1 600 ? 32.838 91.935 -18.577 1.00 25.38 ? 600 HIS A CB 1 ATOM 4973 C CG . HIS A 1 600 ? 31.490 92.533 -18.285 1.00 29.77 ? 600 HIS A CG 1 ATOM 4974 N ND1 . HIS A 1 600 ? 30.604 92.899 -19.279 1.00 32.66 ? 600 HIS A ND1 1 ATOM 4975 C CD2 . HIS A 1 600 ? 30.873 92.820 -17.112 1.00 33.17 ? 600 HIS A CD2 1 ATOM 4976 C CE1 . HIS A 1 600 ? 29.506 93.394 -18.734 1.00 34.27 ? 600 HIS A CE1 1 ATOM 4977 N NE2 . HIS A 1 600 ? 29.643 93.358 -17.420 1.00 34.78 ? 600 HIS A NE2 1 ATOM 4978 N N . ASP A 1 601 ? 33.135 94.533 -20.965 1.00 24.47 ? 601 ASP A N 1 ATOM 4979 C CA . ASP A 1 601 ? 33.238 95.953 -21.166 1.00 25.45 ? 601 ASP A CA 1 ATOM 4980 C C . ASP A 1 601 ? 32.083 96.589 -20.393 1.00 25.93 ? 601 ASP A C 1 ATOM 4981 O O . ASP A 1 601 ? 30.946 96.546 -20.841 1.00 25.33 ? 601 ASP A O 1 ATOM 4982 C CB . ASP A 1 601 ? 33.136 96.239 -22.658 1.00 24.94 ? 601 ASP A CB 1 ATOM 4983 C CG . ASP A 1 601 ? 33.516 97.650 -23.010 1.00 27.23 ? 601 ASP A CG 1 ATOM 4984 O OD1 . ASP A 1 601 ? 33.512 98.514 -22.102 1.00 25.74 ? 601 ASP A OD1 1 ATOM 4985 O OD2 . ASP A 1 601 ? 33.804 97.993 -24.184 1.00 29.09 ? 601 ASP A OD2 1 ATOM 4986 N N . THR A 1 602 ? 32.378 97.148 -19.220 1.00 27.10 ? 602 THR A N 1 ATOM 4987 C CA . THR A 1 602 ? 31.343 97.723 -18.351 1.00 28.79 ? 602 THR A CA 1 ATOM 4988 C C . THR A 1 602 ? 30.756 98.994 -18.939 1.00 28.85 ? 602 THR A C 1 ATOM 4989 O O . THR A 1 602 ? 29.738 99.495 -18.449 1.00 29.59 ? 602 THR A O 1 ATOM 4990 C CB . THR A 1 602 ? 31.888 98.017 -16.928 1.00 28.92 ? 602 THR A CB 1 ATOM 4991 O OG1 . THR A 1 602 ? 33.050 98.862 -17.018 1.00 31.57 ? 602 THR A OG1 1 ATOM 4992 C CG2 . THR A 1 602 ? 32.385 96.732 -16.233 1.00 31.34 ? 602 THR A CG2 1 ATOM 4993 N N . LEU A 1 603 ? 31.391 99.518 -19.985 1.00 28.45 ? 603 LEU A N 1 ATOM 4994 C CA . LEU A 1 603 ? 30.905 100.712 -20.660 1.00 28.14 ? 603 LEU A CA 1 ATOM 4995 C C . LEU A 1 603 ? 29.878 100.392 -21.750 1.00 27.21 ? 603 LEU A C 1 ATOM 4996 O O . LEU A 1 603 ? 28.754 100.902 -21.687 1.00 26.77 ? 603 LEU A O 1 ATOM 4997 C CB . LEU A 1 603 ? 32.064 101.594 -21.168 1.00 29.11 ? 603 LEU A CB 1 ATOM 4998 C CG . LEU A 1 603 ? 32.755 102.551 -20.167 1.00 30.63 ? 603 LEU A CG 1 ATOM 4999 C CD1 . LEU A 1 603 ? 31.773 103.528 -19.497 1.00 32.34 ? 603 LEU A CD1 1 ATOM 5000 C CD2 . LEU A 1 603 ? 33.577 101.826 -19.099 1.00 33.01 ? 603 LEU A CD2 1 ATOM 5001 N N . THR A 1 604 ? 30.242 99.526 -22.709 1.00 25.30 ? 604 THR A N 1 ATOM 5002 C CA . THR A 1 604 ? 29.344 99.077 -23.786 1.00 23.44 ? 604 THR A CA 1 ATOM 5003 C C . THR A 1 604 ? 28.380 97.956 -23.344 1.00 21.75 ? 604 THR A C 1 ATOM 5004 O O . THR A 1 604 ? 27.453 97.606 -24.089 1.00 21.28 ? 604 THR A O 1 ATOM 5005 C CB . THR A 1 604 ? 30.138 98.545 -24.999 1.00 23.92 ? 604 THR A CB 1 ATOM 5006 O OG1 . THR A 1 604 ? 30.974 97.454 -24.568 1.00 23.12 ? 604 THR A OG1 1 ATOM 5007 C CG2 . THR A 1 604 ? 31.126 99.598 -25.552 1.00 24.02 ? 604 THR A CG2 1 ATOM 5008 N N . LYS A 1 605 ? 28.639 97.375 -22.171 1.00 20.58 ? 605 LYS A N 1 ATOM 5009 C CA . LYS A 1 605 ? 27.836 96.262 -21.651 1.00 19.69 ? 605 LYS A CA 1 ATOM 5010 C C . LYS A 1 605 ? 27.865 95.091 -22.634 1.00 19.76 ? 605 LYS A C 1 ATOM 5011 O O . LYS A 1 605 ? 26.830 94.482 -22.936 1.00 20.64 ? 605 LYS A O 1 ATOM 5012 C CB . LYS A 1 605 ? 26.381 96.706 -21.392 1.00 20.06 ? 605 LYS A CB 1 ATOM 5013 C CG . LYS A 1 605 ? 26.273 97.873 -20.438 1.00 20.59 ? 605 LYS A CG 1 ATOM 5014 C CD . LYS A 1 605 ? 26.672 97.431 -19.033 1.00 20.69 ? 605 LYS A CD 1 ATOM 5015 C CE . LYS A 1 605 ? 26.612 98.574 -18.025 1.00 22.38 ? 605 LYS A CE 1 ATOM 5016 N NZ . LYS A 1 605 ? 26.821 98.032 -16.642 1.00 26.64 ? 605 LYS A NZ 1 ATOM 5017 N N . THR A 1 606 ? 29.054 94.819 -23.167 1.00 18.22 ? 606 THR A N 1 ATOM 5018 C CA . THR A 1 606 ? 29.257 93.615 -23.984 1.00 18.00 ? 606 THR A CA 1 ATOM 5019 C C . THR A 1 606 ? 30.471 92.878 -23.485 1.00 16.40 ? 606 THR A C 1 ATOM 5020 O O . THR A 1 606 ? 31.330 93.434 -22.791 1.00 16.43 ? 606 THR A O 1 ATOM 5021 C CB . THR A 1 606 ? 29.525 93.965 -25.445 1.00 18.77 ? 606 THR A CB 1 ATOM 5022 O OG1 . THR A 1 606 ? 30.678 94.819 -25.502 1.00 21.52 ? 606 THR A OG1 1 ATOM 5023 C CG2 . THR A 1 606 ? 28.331 94.738 -26.106 1.00 18.17 ? 606 THR A CG2 1 ATOM 5024 N N . ILE A 1 607 ? 30.549 91.602 -23.857 1.00 15.05 ? 607 ILE A N 1 ATOM 5025 C CA . ILE A 1 607 ? 31.732 90.774 -23.578 1.00 13.65 ? 607 ILE A CA 1 ATOM 5026 C C . ILE A 1 607 ? 32.391 90.536 -24.935 1.00 13.28 ? 607 ILE A C 1 ATOM 5027 O O . ILE A 1 607 ? 31.760 89.981 -25.855 1.00 12.54 ? 607 ILE A O 1 ATOM 5028 C CB . ILE A 1 607 ? 31.283 89.450 -22.994 1.00 13.66 ? 607 ILE A CB 1 ATOM 5029 C CG1 . ILE A 1 607 ? 30.412 89.696 -21.759 1.00 15.56 ? 607 ILE A CG1 1 ATOM 5030 C CG2 . ILE A 1 607 ? 32.515 88.552 -22.652 1.00 13.36 ? 607 ILE A CG2 1 ATOM 5031 C CD1 . ILE A 1 607 ? 29.704 88.455 -21.257 1.00 18.38 ? 607 ILE A CD1 1 ATOM 5032 N N . HIS A 1 608 ? 33.618 91.016 -25.101 1.00 13.95 ? 608 HIS A N 1 ATOM 5033 C CA . HIS A 1 608 ? 34.222 91.024 -26.433 1.00 14.59 ? 608 HIS A CA 1 ATOM 5034 C C . HIS A 1 608 ? 35.724 90.851 -26.335 1.00 13.58 ? 608 HIS A C 1 ATOM 5035 O O . HIS A 1 608 ? 36.309 91.121 -25.287 1.00 14.06 ? 608 HIS A O 1 ATOM 5036 C CB . HIS A 1 608 ? 33.865 92.297 -27.205 1.00 16.61 ? 608 HIS A CB 1 ATOM 5037 C CG . HIS A 1 608 ? 34.397 93.553 -26.590 1.00 20.10 ? 608 HIS A CG 1 ATOM 5038 N ND1 . HIS A 1 608 ? 35.712 93.952 -26.718 1.00 25.88 ? 608 HIS A ND1 1 ATOM 5039 C CD2 . HIS A 1 608 ? 33.792 94.505 -25.837 1.00 23.26 ? 608 HIS A CD2 1 ATOM 5040 C CE1 . HIS A 1 608 ? 35.892 95.095 -26.078 1.00 25.81 ? 608 HIS A CE1 1 ATOM 5041 N NE2 . HIS A 1 608 ? 34.739 95.459 -25.546 1.00 25.37 ? 608 HIS A NE2 1 ATOM 5042 N N . PRO A 1 609 ? 36.338 90.354 -27.394 1.00 12.83 ? 609 PRO A N 1 ATOM 5043 C CA . PRO A 1 609 ? 37.772 90.084 -27.374 1.00 12.81 ? 609 PRO A CA 1 ATOM 5044 C C . PRO A 1 609 ? 38.613 91.262 -27.809 1.00 13.66 ? 609 PRO A C 1 ATOM 5045 O O . PRO A 1 609 ? 38.213 92.033 -28.694 1.00 15.32 ? 609 PRO A O 1 ATOM 5046 C CB . PRO A 1 609 ? 37.913 88.962 -28.401 1.00 12.50 ? 609 PRO A CB 1 ATOM 5047 C CG . PRO A 1 609 ? 36.819 89.197 -29.397 1.00 13.03 ? 609 PRO A CG 1 ATOM 5048 C CD . PRO A 1 609 ? 35.727 89.929 -28.669 1.00 12.20 ? 609 PRO A CD 1 ATOM 5049 N N . GLN A 1 610 ? 39.787 91.351 -27.198 1.00 13.44 ? 610 GLN A N 1 ATOM 5050 C CA . GLN A 1 610 ? 40.791 92.310 -27.608 1.00 15.24 ? 610 GLN A CA 1 ATOM 5051 C C . GLN A 1 610 ? 42.057 91.547 -27.976 1.00 13.25 ? 610 GLN A C 1 ATOM 5052 O O . GLN A 1 610 ? 42.371 90.556 -27.338 1.00 14.33 ? 610 GLN A O 1 ATOM 5053 C CB . GLN A 1 610 ? 41.043 93.326 -26.493 1.00 16.51 ? 610 GLN A CB 1 ATOM 5054 C CG . GLN A 1 610 ? 39.825 94.250 -26.221 1.00 23.51 ? 610 GLN A CG 1 ATOM 5055 C CD . GLN A 1 610 ? 39.578 95.277 -27.328 1.00 28.57 ? 610 GLN A CD 1 ATOM 5056 O OE1 . GLN A 1 610 ? 40.285 96.285 -27.406 1.00 33.14 ? 610 GLN A OE1 1 ATOM 5057 N NE2 . GLN A 1 610 ? 38.569 95.034 -28.171 1.00 30.18 ? 610 GLN A NE2 1 ATOM 5058 N N . GLY A 1 611 ? 42.749 92.006 -29.006 1.00 13.94 ? 611 GLY A N 1 ATOM 5059 C CA . GLY A 1 611 ? 43.953 91.331 -29.469 1.00 13.71 ? 611 GLY A CA 1 ATOM 5060 C C . GLY A 1 611 ? 45.172 92.100 -28.996 1.00 14.74 ? 611 GLY A C 1 ATOM 5061 O O . GLY A 1 611 ? 45.144 93.326 -28.883 1.00 14.72 ? 611 GLY A O 1 ATOM 5062 N N . SER A 1 612 ? 46.235 91.372 -28.684 1.00 14.63 ? 612 SER A N 1 ATOM 5063 C CA . SER A 1 612 ? 47.492 92.021 -28.341 1.00 14.33 ? 612 SER A CA 1 ATOM 5064 C C . SER A 1 612 ? 48.165 92.547 -29.585 1.00 14.37 ? 612 SER A C 1 ATOM 5065 O O . SER A 1 612 ? 48.106 91.924 -30.650 1.00 14.25 ? 612 SER A O 1 ATOM 5066 C CB . SER A 1 612 ? 48.403 91.002 -27.661 1.00 14.39 ? 612 SER A CB 1 ATOM 5067 O OG . SER A 1 612 ? 49.685 91.580 -27.466 1.00 15.01 ? 612 SER A OG 1 ATOM 5068 N N . THR A 1 613 ? 48.846 93.695 -29.469 1.00 15.94 ? 613 THR A N 1 ATOM 5069 C CA . THR A 1 613 ? 49.607 94.196 -30.605 1.00 16.85 ? 613 THR A CA 1 ATOM 5070 C C . THR A 1 613 ? 51.111 93.961 -30.444 1.00 17.86 ? 613 THR A C 1 ATOM 5071 O O . THR A 1 613 ? 51.902 94.442 -31.269 1.00 18.53 ? 613 THR A O 1 ATOM 5072 C CB . THR A 1 613 ? 49.368 95.691 -30.854 1.00 17.55 ? 613 THR A CB 1 ATOM 5073 O OG1 . THR A 1 613 ? 49.857 96.411 -29.720 1.00 17.52 ? 613 THR A OG1 1 ATOM 5074 C CG2 . THR A 1 613 ? 47.868 96.017 -30.890 1.00 18.10 ? 613 THR A CG2 1 ATOM 5075 N N . THR A 1 614 ? 51.507 93.226 -29.407 1.00 16.91 ? 614 THR A N 1 ATOM 5076 C CA . THR A 1 614 ? 52.942 92.945 -29.203 1.00 17.95 ? 614 THR A CA 1 ATOM 5077 C C . THR A 1 614 ? 53.240 91.506 -28.791 1.00 17.34 ? 614 THR A C 1 ATOM 5078 O O . THR A 1 614 ? 54.401 91.164 -28.551 1.00 17.83 ? 614 THR A O 1 ATOM 5079 C CB . THR A 1 614 ? 53.496 93.809 -28.079 1.00 18.27 ? 614 THR A CB 1 ATOM 5080 O OG1 . THR A 1 614 ? 52.645 93.667 -26.943 1.00 18.60 ? 614 THR A OG1 1 ATOM 5081 C CG2 . THR A 1 614 ? 53.489 95.317 -28.428 1.00 19.88 ? 614 THR A CG2 1 ATOM 5082 N N . LYS A 1 615 ? 52.215 90.673 -28.631 1.00 16.16 ? 615 LYS A N 1 ATOM 5083 C CA . LYS A 1 615 ? 52.492 89.288 -28.294 1.00 16.35 ? 615 LYS A CA 1 ATOM 5084 C C . LYS A 1 615 ? 51.610 88.414 -29.142 1.00 14.05 ? 615 LYS A C 1 ATOM 5085 O O . LYS A 1 615 ? 50.494 88.813 -29.500 1.00 13.62 ? 615 LYS A O 1 ATOM 5086 C CB . LYS A 1 615 ? 52.428 89.006 -26.783 1.00 18.21 ? 615 LYS A CB 1 ATOM 5087 C CG . LYS A 1 615 ? 51.177 88.556 -26.136 1.00 20.43 ? 615 LYS A CG 1 ATOM 5088 C CD . LYS A 1 615 ? 51.478 88.516 -24.599 1.00 21.26 ? 615 LYS A CD 1 ATOM 5089 C CE . LYS A 1 615 ? 50.303 88.025 -23.749 1.00 24.51 ? 615 LYS A CE 1 ATOM 5090 N NZ . LYS A 1 615 ? 50.580 88.016 -22.249 1.00 23.77 ? 615 LYS A NZ 1 ATOM 5091 N N . TYR A 1 616 ? 52.139 87.246 -29.497 1.00 11.48 ? 616 TYR A N 1 ATOM 5092 C CA . TYR A 1 616 ? 51.502 86.369 -30.486 1.00 11.21 ? 616 TYR A CA 1 ATOM 5093 C C . TYR A 1 616 ? 51.628 84.945 -30.017 1.00 10.29 ? 616 TYR A C 1 ATOM 5094 O O . TYR A 1 616 ? 52.506 84.666 -29.205 1.00 11.06 ? 616 TYR A O 1 ATOM 5095 C CB . TYR A 1 616 ? 52.177 86.534 -31.866 1.00 11.54 ? 616 TYR A CB 1 ATOM 5096 C CG . TYR A 1 616 ? 52.097 87.975 -32.279 1.00 13.62 ? 616 TYR A CG 1 ATOM 5097 C CD1 . TYR A 1 616 ? 50.919 88.476 -32.835 1.00 15.44 ? 616 TYR A CD1 1 ATOM 5098 C CD2 . TYR A 1 616 ? 53.137 88.856 -31.997 1.00 13.72 ? 616 TYR A CD2 1 ATOM 5099 C CE1 . TYR A 1 616 ? 50.792 89.799 -33.137 1.00 16.78 ? 616 TYR A CE1 1 ATOM 5100 C CE2 . TYR A 1 616 ? 53.014 90.224 -32.304 1.00 15.81 ? 616 TYR A CE2 1 ATOM 5101 C CZ . TYR A 1 616 ? 51.831 90.663 -32.872 1.00 15.25 ? 616 TYR A CZ 1 ATOM 5102 O OH . TYR A 1 616 ? 51.666 91.991 -33.224 1.00 19.89 ? 616 TYR A OH 1 ATOM 5103 N N . ARG A 1 617 ? 50.756 84.069 -30.502 1.00 9.66 ? 617 ARG A N 1 ATOM 5104 C CA . ARG A 1 617 ? 50.830 82.655 -30.140 1.00 11.79 ? 617 ARG A CA 1 ATOM 5105 C C . ARG A 1 617 ? 51.451 81.895 -31.284 1.00 10.97 ? 617 ARG A C 1 ATOM 5106 O O . ARG A 1 617 ? 50.964 82.017 -32.413 1.00 11.23 ? 617 ARG A O 1 ATOM 5107 C CB . ARG A 1 617 ? 49.434 82.077 -29.961 1.00 12.57 ? 617 ARG A CB 1 ATOM 5108 C CG . ARG A 1 617 ? 48.720 82.422 -28.706 1.00 17.48 ? 617 ARG A CG 1 ATOM 5109 C CD . ARG A 1 617 ? 47.363 81.719 -28.608 1.00 16.18 ? 617 ARG A CD 1 ATOM 5110 N NE . ARG A 1 617 ? 47.429 80.251 -28.599 1.00 18.73 ? 617 ARG A NE 1 ATOM 5111 C CZ . ARG A 1 617 ? 46.727 79.433 -29.389 1.00 21.65 ? 617 ARG A CZ 1 ATOM 5112 N NH1 . ARG A 1 617 ? 45.884 79.914 -30.310 1.00 21.17 ? 617 ARG A NH1 1 ATOM 5113 N NH2 . ARG A 1 617 ? 46.869 78.121 -29.266 1.00 22.50 ? 617 ARG A NH2 1 ATOM 5114 N N . ILE A 1 618 ? 52.467 81.083 -31.038 1.00 8.86 ? 618 ILE A N 1 ATOM 5115 C CA . ILE A 1 618 ? 52.970 80.184 -32.053 1.00 9.52 ? 618 ILE A CA 1 ATOM 5116 C C . ILE A 1 618 ? 52.639 78.751 -31.657 1.00 9.66 ? 618 ILE A C 1 ATOM 5117 O O . ILE A 1 618 ? 52.807 78.354 -30.487 1.00 10.23 ? 618 ILE A O 1 ATOM 5118 C CB . ILE A 1 618 ? 54.449 80.375 -32.288 1.00 10.17 ? 618 ILE A CB 1 ATOM 5119 C CG1 . ILE A 1 618 ? 54.865 79.444 -33.411 1.00 11.03 ? 618 ILE A CG1 1 ATOM 5120 C CG2 . ILE A 1 618 ? 55.285 80.062 -31.028 1.00 10.91 ? 618 ILE A CG2 1 ATOM 5121 C CD1 . ILE A 1 618 ? 56.026 79.921 -34.194 1.00 13.27 ? 618 ILE A CD1 1 ATOM 5122 N N . ILE A 1 619 ? 52.164 77.984 -32.627 1.00 9.09 ? 619 ILE A N 1 ATOM 5123 C CA . ILE A 1 619 ? 51.660 76.629 -32.417 1.00 10.59 ? 619 ILE A CA 1 ATOM 5124 C C . ILE A 1 619 ? 52.408 75.689 -33.349 1.00 10.17 ? 619 ILE A C 1 ATOM 5125 O O . ILE A 1 619 ? 52.624 76.014 -34.520 1.00 9.80 ? 619 ILE A O 1 ATOM 5126 C CB . ILE A 1 619 ? 50.154 76.582 -32.791 1.00 12.01 ? 619 ILE A CB 1 ATOM 5127 C CG1 . ILE A 1 619 ? 49.387 77.612 -31.962 1.00 15.44 ? 619 ILE A CG1 1 ATOM 5128 C CG2 . ILE A 1 619 ? 49.559 75.188 -32.601 1.00 15.56 ? 619 ILE A CG2 1 ATOM 5129 C CD1 . ILE A 1 619 ? 48.279 78.315 -32.723 1.00 18.47 ? 619 ILE A CD1 1 ATOM 5130 N N . PHE A 1 620 ? 52.830 74.536 -32.865 1.00 7.97 ? 620 PHE A N 1 ATOM 5131 C CA . PHE A 1 620 ? 53.469 73.561 -33.742 1.00 8.17 ? 620 PHE A CA 1 ATOM 5132 C C . PHE A 1 620 ? 53.317 72.184 -33.117 1.00 8.88 ? 620 PHE A C 1 ATOM 5133 O O . PHE A 1 620 ? 53.005 72.061 -31.925 1.00 8.91 ? 620 PHE A O 1 ATOM 5134 C CB . PHE A 1 620 ? 54.943 73.866 -33.991 1.00 8.38 ? 620 PHE A CB 1 ATOM 5135 C CG . PHE A 1 620 ? 55.795 73.819 -32.743 1.00 7.64 ? 620 PHE A CG 1 ATOM 5136 C CD1 . PHE A 1 620 ? 55.945 74.955 -31.942 1.00 8.95 ? 620 PHE A CD1 1 ATOM 5137 C CD2 . PHE A 1 620 ? 56.516 72.662 -32.395 1.00 7.91 ? 620 PHE A CD2 1 ATOM 5138 C CE1 . PHE A 1 620 ? 56.766 74.897 -30.792 1.00 9.94 ? 620 PHE A CE1 1 ATOM 5139 C CE2 . PHE A 1 620 ? 57.307 72.611 -31.254 1.00 8.74 ? 620 PHE A CE2 1 ATOM 5140 C CZ . PHE A 1 620 ? 57.430 73.726 -30.459 1.00 9.48 ? 620 PHE A CZ 1 ATOM 5141 N N . LYS A 1 621 ? 53.532 71.155 -33.923 1.00 8.69 ? 621 LYS A N 1 ATOM 5142 C CA . LYS A 1 621 ? 53.373 69.798 -33.445 1.00 9.79 ? 621 LYS A CA 1 ATOM 5143 C C . LYS A 1 621 ? 54.681 69.304 -32.846 1.00 10.14 ? 621 LYS A C 1 ATOM 5144 O O . LYS A 1 621 ? 55.724 69.314 -33.496 1.00 10.80 ? 621 LYS A O 1 ATOM 5145 C CB . LYS A 1 621 ? 52.944 68.909 -34.609 1.00 10.35 ? 621 LYS A CB 1 ATOM 5146 C CG . LYS A 1 621 ? 52.555 67.485 -34.156 1.00 11.97 ? 621 LYS A CG 1 ATOM 5147 C CD . LYS A 1 621 ? 51.743 66.746 -35.213 1.00 20.00 ? 621 LYS A CD 1 ATOM 5148 C CE . LYS A 1 621 ? 52.371 66.873 -36.577 1.00 23.21 ? 621 LYS A CE 1 ATOM 5149 N NZ . LYS A 1 621 ? 51.536 66.168 -37.603 1.00 26.89 ? 621 LYS A NZ 1 ATOM 5150 N N . ALA A 1 622 ? 54.651 68.955 -31.558 1.00 10.10 ? 622 ALA A N 1 ATOM 5151 C CA . ALA A 1 622 ? 55.826 68.417 -30.900 1.00 9.51 ? 622 ALA A CA 1 ATOM 5152 C C . ALA A 1 622 ? 55.728 66.900 -30.913 1.00 10.00 ? 622 ALA A C 1 ATOM 5153 O O . ALA A 1 622 ? 54.651 66.354 -30.720 1.00 11.31 ? 622 ALA A O 1 ATOM 5154 C CB . ALA A 1 622 ? 55.877 68.904 -29.448 1.00 10.31 ? 622 ALA A CB 1 ATOM 5155 N N . ARG A 1 623 ? 56.845 66.233 -31.175 1.00 8.91 ? 623 ARG A N 1 ATOM 5156 C CA . ARG A 1 623 ? 56.898 64.761 -31.204 1.00 9.43 ? 623 ARG A CA 1 ATOM 5157 C C . ARG A 1 623 ? 57.900 64.315 -30.162 1.00 8.99 ? 623 ARG A C 1 ATOM 5158 O O . ARG A 1 623 ? 59.063 64.694 -30.210 1.00 10.45 ? 623 ARG A O 1 ATOM 5159 C CB . ARG A 1 623 ? 57.338 64.258 -32.583 1.00 10.14 ? 623 ARG A CB 1 ATOM 5160 C CG . ARG A 1 623 ? 57.333 62.718 -32.672 1.00 12.69 ? 623 ARG A CG 1 ATOM 5161 C CD . ARG A 1 623 ? 57.417 62.142 -34.115 1.00 14.73 ? 623 ARG A CD 1 ATOM 5162 N NE . ARG A 1 623 ? 57.589 60.680 -34.101 1.00 17.79 ? 623 ARG A NE 1 ATOM 5163 C CZ . ARG A 1 623 ? 58.779 60.088 -34.055 1.00 21.16 ? 623 ARG A CZ 1 ATOM 5164 N NH1 . ARG A 1 623 ? 59.887 60.822 -34.047 1.00 23.81 ? 623 ARG A NH1 1 ATOM 5165 N NH2 . ARG A 1 623 ? 58.862 58.765 -34.002 1.00 21.44 ? 623 ARG A NH2 1 ATOM 5166 N N . VAL A 1 624 ? 57.414 63.561 -29.174 1.00 7.42 ? 624 VAL A N 1 ATOM 5167 C CA . VAL A 1 624 ? 58.193 63.330 -27.966 1.00 6.55 ? 624 VAL A CA 1 ATOM 5168 C C . VAL A 1 624 ? 58.251 61.837 -27.665 1.00 6.04 ? 624 VAL A C 1 ATOM 5169 O O . VAL A 1 624 ? 57.229 61.182 -27.777 1.00 6.41 ? 624 VAL A O 1 ATOM 5170 C CB . VAL A 1 624 ? 57.553 64.084 -26.780 1.00 7.73 ? 624 VAL A CB 1 ATOM 5171 C CG1 . VAL A 1 624 ? 58.473 64.092 -25.571 1.00 8.19 ? 624 VAL A CG1 1 ATOM 5172 C CG2 . VAL A 1 624 ? 57.208 65.523 -27.171 1.00 9.27 ? 624 VAL A CG2 1 ATOM 5173 N N . PRO A 1 625 ? 59.438 61.323 -27.314 1.00 7.22 ? 625 PRO A N 1 ATOM 5174 C CA . PRO A 1 625 ? 59.562 59.878 -27.055 1.00 7.12 ? 625 PRO A CA 1 ATOM 5175 C C . PRO A 1 625 ? 58.731 59.425 -25.856 1.00 6.91 ? 625 PRO A C 1 ATOM 5176 O O . PRO A 1 625 ? 58.275 60.227 -25.025 1.00 6.47 ? 625 PRO A O 1 ATOM 5177 C CB . PRO A 1 625 ? 61.050 59.685 -26.730 1.00 8.49 ? 625 PRO A CB 1 ATOM 5178 C CG . PRO A 1 625 ? 61.760 60.905 -27.276 1.00 8.92 ? 625 PRO A CG 1 ATOM 5179 C CD . PRO A 1 625 ? 60.730 62.014 -27.198 1.00 8.27 ? 625 PRO A CD 1 ATOM 5180 N N . PRO A 1 626 ? 58.554 58.122 -25.720 1.00 7.13 ? 626 PRO A N 1 ATOM 5181 C CA . PRO A 1 626 ? 57.920 57.564 -24.518 1.00 6.76 ? 626 PRO A CA 1 ATOM 5182 C C . PRO A 1 626 ? 58.651 57.991 -23.256 1.00 7.27 ? 626 PRO A C 1 ATOM 5183 O O . PRO A 1 626 ? 59.840 57.881 -23.156 1.00 6.88 ? 626 PRO A O 1 ATOM 5184 C CB . PRO A 1 626 ? 58.036 56.046 -24.730 1.00 7.41 ? 626 PRO A CB 1 ATOM 5185 C CG . PRO A 1 626 ? 58.336 55.877 -26.219 1.00 7.69 ? 626 PRO A CG 1 ATOM 5186 C CD . PRO A 1 626 ? 59.157 57.074 -26.561 1.00 8.15 ? 626 PRO A CD 1 ATOM 5187 N N . MET A 1 627 ? 57.909 58.491 -22.291 1.00 6.19 ? 627 MET A N 1 ATOM 5188 C CA . MET A 1 627 ? 58.532 58.915 -21.024 1.00 6.46 ? 627 MET A CA 1 ATOM 5189 C C . MET A 1 627 ? 59.800 59.724 -21.249 1.00 5.83 ? 627 MET A C 1 ATOM 5190 O O . MET A 1 627 ? 60.800 59.554 -20.579 1.00 7.38 ? 627 MET A O 1 ATOM 5191 C CB . MET A 1 627 ? 58.831 57.709 -20.111 1.00 7.19 ? 627 MET A CB 1 ATOM 5192 C CG . MET A 1 627 ? 57.536 57.000 -19.771 1.00 6.50 ? 627 MET A CG 1 ATOM 5193 S SD . MET A 1 627 ? 57.789 55.343 -19.054 1.00 11.22 ? 627 MET A SD 1 ATOM 5194 C CE . MET A 1 627 ? 58.626 55.681 -17.524 1.00 12.00 ? 627 MET A CE 1 ATOM 5195 N N . GLY A 1 628 ? 59.702 60.650 -22.215 1.00 6.48 ? 628 GLY A N 1 ATOM 5196 C CA . GLY A 1 628 ? 60.895 61.305 -22.735 1.00 7.00 ? 628 GLY A CA 1 ATOM 5197 C C . GLY A 1 628 ? 60.784 62.794 -22.941 1.00 6.50 ? 628 GLY A C 1 ATOM 5198 O O . GLY A 1 628 ? 59.796 63.426 -22.546 1.00 6.53 ? 628 GLY A O 1 ATOM 5199 N N . LEU A 1 629 ? 61.813 63.348 -23.568 1.00 6.64 ? 629 LEU A N 1 ATOM 5200 C CA . LEU A 1 629 ? 61.916 64.802 -23.799 1.00 6.90 ? 629 LEU A CA 1 ATOM 5201 C C . LEU A 1 629 ? 62.350 65.086 -25.203 1.00 7.18 ? 629 LEU A C 1 ATOM 5202 O O . LEU A 1 629 ? 63.131 64.315 -25.796 1.00 7.07 ? 629 LEU A O 1 ATOM 5203 C CB . LEU A 1 629 ? 62.965 65.429 -22.872 1.00 6.59 ? 629 LEU A CB 1 ATOM 5204 C CG . LEU A 1 629 ? 62.748 65.259 -21.360 1.00 7.10 ? 629 LEU A CG 1 ATOM 5205 C CD1 . LEU A 1 629 ? 64.022 65.485 -20.580 1.00 7.45 ? 629 LEU A CD1 1 ATOM 5206 C CD2 . LEU A 1 629 ? 61.701 66.251 -20.907 1.00 8.12 ? 629 LEU A CD2 1 ATOM 5207 N N . ALA A 1 630 ? 61.869 66.218 -25.734 1.00 6.68 ? 630 ALA A N 1 ATOM 5208 C CA . ALA A 1 630 ? 62.248 66.665 -27.087 1.00 8.59 ? 630 ALA A CA 1 ATOM 5209 C C . ALA A 1 630 ? 62.455 68.177 -27.057 1.00 8.50 ? 630 ALA A C 1 ATOM 5210 O O . ALA A 1 630 ? 61.675 68.917 -26.462 1.00 8.68 ? 630 ALA A O 1 ATOM 5211 C CB . ALA A 1 630 ? 61.184 66.316 -28.070 1.00 9.25 ? 630 ALA A CB 1 ATOM 5212 N N . THR A 1 631 ? 63.536 68.623 -27.693 1.00 8.09 ? 631 THR A N 1 ATOM 5213 C CA . THR A 1 631 ? 63.922 70.041 -27.687 1.00 8.38 ? 631 THR A CA 1 ATOM 5214 C C . THR A 1 631 ? 63.639 70.643 -29.047 1.00 8.35 ? 631 THR A C 1 ATOM 5215 O O . THR A 1 631 ? 63.923 70.023 -30.093 1.00 8.74 ? 631 THR A O 1 ATOM 5216 C CB . THR A 1 631 ? 65.435 70.127 -27.441 1.00 8.39 ? 631 THR A CB 1 ATOM 5217 O OG1 . THR A 1 631 ? 65.740 69.495 -26.188 1.00 8.79 ? 631 THR A OG1 1 ATOM 5218 C CG2 . THR A 1 631 ? 65.932 71.563 -27.280 1.00 10.97 ? 631 THR A CG2 1 ATOM 5219 N N . TYR A 1 632 ? 63.115 71.858 -29.018 1.00 7.52 ? 632 TYR A N 1 ATOM 5220 C CA . TYR A 1 632 ? 62.904 72.611 -30.240 1.00 7.87 ? 632 TYR A CA 1 ATOM 5221 C C . TYR A 1 632 ? 63.464 74.009 -30.040 1.00 8.36 ? 632 TYR A C 1 ATOM 5222 O O . TYR A 1 632 ? 63.756 74.438 -28.922 1.00 8.06 ? 632 TYR A O 1 ATOM 5223 C CB . TYR A 1 632 ? 61.421 72.715 -30.506 1.00 8.68 ? 632 TYR A CB 1 ATOM 5224 C CG . TYR A 1 632 ? 60.810 71.408 -30.932 1.00 8.59 ? 632 TYR A CG 1 ATOM 5225 C CD1 . TYR A 1 632 ? 60.404 70.465 -29.980 1.00 8.64 ? 632 TYR A CD1 1 ATOM 5226 C CD2 . TYR A 1 632 ? 60.572 71.132 -32.289 1.00 11.13 ? 632 TYR A CD2 1 ATOM 5227 C CE1 . TYR A 1 632 ? 59.833 69.232 -30.364 1.00 9.89 ? 632 TYR A CE1 1 ATOM 5228 C CE2 . TYR A 1 632 ? 60.002 69.931 -32.696 1.00 11.05 ? 632 TYR A CE2 1 ATOM 5229 C CZ . TYR A 1 632 ? 59.646 68.970 -31.719 1.00 9.89 ? 632 TYR A CZ 1 ATOM 5230 O OH . TYR A 1 632 ? 59.073 67.772 -32.160 1.00 12.62 ? 632 TYR A OH 1 ATOM 5231 N N . VAL A 1 633 ? 63.607 74.730 -31.163 1.00 7.59 ? 633 VAL A N 1 ATOM 5232 C CA . VAL A 1 633 ? 64.151 76.088 -31.154 1.00 8.49 ? 633 VAL A CA 1 ATOM 5233 C C . VAL A 1 633 ? 63.200 77.036 -31.886 1.00 7.52 ? 633 VAL A C 1 ATOM 5234 O O . VAL A 1 633 ? 62.721 76.694 -32.963 1.00 8.43 ? 633 VAL A O 1 ATOM 5235 C CB . VAL A 1 633 ? 65.536 76.156 -31.846 1.00 8.90 ? 633 VAL A CB 1 ATOM 5236 C CG1 . VAL A 1 633 ? 66.133 77.571 -31.716 1.00 11.36 ? 633 VAL A CG1 1 ATOM 5237 C CG2 . VAL A 1 633 ? 66.467 75.142 -31.207 1.00 11.23 ? 633 VAL A CG2 1 ATOM 5238 N N . LEU A 1 634 ? 62.910 78.177 -31.244 1.00 7.84 ? 634 LEU A N 1 ATOM 5239 C CA . LEU A 1 634 ? 62.106 79.239 -31.866 1.00 8.86 ? 634 LEU A CA 1 ATOM 5240 C C . LEU A 1 634 ? 63.049 80.375 -32.231 1.00 9.09 ? 634 LEU A C 1 ATOM 5241 O O . LEU A 1 634 ? 63.827 80.811 -31.392 1.00 9.55 ? 634 LEU A O 1 ATOM 5242 C CB . LEU A 1 634 ? 61.068 79.775 -30.854 1.00 9.38 ? 634 LEU A CB 1 ATOM 5243 C CG . LEU A 1 634 ? 60.163 78.777 -30.126 1.00 14.15 ? 634 LEU A CG 1 ATOM 5244 C CD1 . LEU A 1 634 ? 59.114 79.506 -29.326 1.00 15.16 ? 634 LEU A CD1 1 ATOM 5245 C CD2 . LEU A 1 634 ? 59.505 77.849 -31.074 1.00 16.48 ? 634 LEU A CD2 1 ATOM 5246 N N . THR A 1 635 ? 62.992 80.803 -33.510 1.00 9.53 ? 635 THR A N 1 ATOM 5247 C CA . THR A 1 635 ? 63.917 81.826 -34.018 1.00 9.20 ? 635 THR A CA 1 ATOM 5248 C C . THR A 1 635 ? 63.136 82.949 -34.686 1.00 9.58 ? 635 THR A C 1 ATOM 5249 O O . THR A 1 635 ? 62.218 82.692 -35.474 1.00 10.31 ? 635 THR A O 1 ATOM 5250 C CB . THR A 1 635 ? 64.830 81.171 -35.055 1.00 10.30 ? 635 THR A CB 1 ATOM 5251 O OG1 . THR A 1 635 ? 65.587 80.124 -34.430 1.00 12.28 ? 635 THR A OG1 1 ATOM 5252 C CG2 . THR A 1 635 ? 65.881 82.168 -35.572 1.00 11.08 ? 635 THR A CG2 1 ATOM 5253 N N . ILE A 1 636 ? 63.551 84.181 -34.380 1.00 11.35 ? 636 ILE A N 1 ATOM 5254 C CA . ILE A 1 636 ? 62.892 85.331 -34.981 1.00 13.12 ? 636 ILE A CA 1 ATOM 5255 C C . ILE A 1 636 ? 63.502 85.585 -36.368 1.00 14.37 ? 636 ILE A C 1 ATOM 5256 O O . ILE A 1 636 ? 64.676 85.263 -36.610 1.00 14.52 ? 636 ILE A O 1 ATOM 5257 C CB . ILE A 1 636 ? 63.010 86.568 -34.064 1.00 12.94 ? 636 ILE A CB 1 ATOM 5258 C CG1 . ILE A 1 636 ? 62.034 87.666 -34.502 1.00 13.37 ? 636 ILE A CG1 1 ATOM 5259 C CG2 . ILE A 1 636 ? 64.467 87.073 -34.000 1.00 14.14 ? 636 ILE A CG2 1 ATOM 5260 C CD1 . ILE A 1 636 ? 62.046 88.858 -33.581 1.00 15.22 ? 636 ILE A CD1 1 ATOM 5261 N N . SER A 1 637 ? 62.686 86.112 -37.275 1.00 16.12 ? 637 SER A N 1 ATOM 5262 C CA . SER A 1 637 ? 63.222 86.630 -38.544 1.00 19.42 ? 637 SER A CA 1 ATOM 5263 C C . SER A 1 637 ? 62.600 87.991 -38.833 1.00 21.16 ? 637 SER A C 1 ATOM 5264 O O . SER A 1 637 ? 61.716 88.408 -38.105 1.00 20.36 ? 637 SER A O 1 ATOM 5265 C CB . SER A 1 637 ? 62.962 85.645 -39.683 1.00 20.99 ? 637 SER A CB 1 ATOM 5266 O OG . SER A 1 637 ? 61.577 85.506 -39.920 1.00 22.92 ? 637 SER A OG 1 ATOM 5267 N N . ASP A 1 638 ? 63.068 88.678 -39.886 1.00 23.33 ? 638 ASP A N 1 ATOM 5268 C CA . ASP A 1 638 ? 62.555 90.020 -40.221 1.00 25.34 ? 638 ASP A CA 1 ATOM 5269 C C . ASP A 1 638 ? 61.188 90.010 -40.913 1.00 25.15 ? 638 ASP A C 1 ATOM 5270 O O . ASP A 1 638 ? 60.488 91.031 -40.950 1.00 26.66 ? 638 ASP A O 1 ATOM 5271 C CB . ASP A 1 638 ? 63.547 90.778 -41.115 1.00 26.56 ? 638 ASP A CB 1 ATOM 5272 C CG . ASP A 1 638 ? 64.909 90.978 -40.462 1.00 30.52 ? 638 ASP A CG 1 ATOM 5273 O OD1 . ASP A 1 638 ? 65.016 90.886 -39.214 1.00 35.58 ? 638 ASP A OD1 1 ATOM 5274 O OD2 . ASP A 1 638 ? 65.938 91.249 -41.124 1.00 36.49 ? 638 ASP A OD2 1 ATOM 5275 N N . SER A 1 639 ? 60.806 88.862 -41.460 1.00 24.57 ? 639 SER A N 1 ATOM 5276 C CA . SER A 1 639 ? 59.614 88.762 -42.285 1.00 24.45 ? 639 SER A CA 1 ATOM 5277 C C . SER A 1 639 ? 59.026 87.365 -42.172 1.00 23.89 ? 639 SER A C 1 ATOM 5278 O O . SER A 1 639 ? 59.613 86.503 -41.501 1.00 23.06 ? 639 SER A O 1 ATOM 5279 C CB . SER A 1 639 ? 59.963 89.084 -43.744 1.00 24.32 ? 639 SER A CB 1 ATOM 5280 O OG . SER A 1 639 ? 60.907 88.154 -44.261 1.00 26.32 ? 639 SER A OG 1 ATOM 5281 N N . LYS A 1 640 ? 57.876 87.138 -42.816 1.00 23.12 ? 640 LYS A N 1 ATOM 5282 C CA . LYS A 1 640 ? 57.216 85.820 -42.787 1.00 22.92 ? 640 LYS A CA 1 ATOM 5283 C C . LYS A 1 640 ? 58.188 84.677 -43.078 1.00 21.88 ? 640 LYS A C 1 ATOM 5284 O O . LYS A 1 640 ? 58.786 84.614 -44.155 1.00 22.23 ? 640 LYS A O 1 ATOM 5285 C CB . LYS A 1 640 ? 56.043 85.738 -43.767 1.00 23.23 ? 640 LYS A CB 1 ATOM 5286 C CG . LYS A 1 640 ? 54.791 86.512 -43.411 1.00 26.58 ? 640 LYS A CG 1 ATOM 5287 C CD . LYS A 1 640 ? 53.618 85.954 -44.215 1.00 28.77 ? 640 LYS A CD 1 ATOM 5288 C CE . LYS A 1 640 ? 52.663 87.045 -44.648 1.00 29.66 ? 640 LYS A CE 1 ATOM 5289 N NZ . LYS A 1 640 ? 51.418 86.474 -45.236 1.00 30.91 ? 640 LYS A NZ 1 ATOM 5290 N N . PRO A 1 641 ? 58.364 83.779 -42.114 1.00 20.41 ? 641 PRO A N 1 ATOM 5291 C CA . PRO A 1 641 ? 59.155 82.568 -42.331 1.00 19.61 ? 641 PRO A CA 1 ATOM 5292 C C . PRO A 1 641 ? 58.504 81.605 -43.307 1.00 18.74 ? 641 PRO A C 1 ATOM 5293 O O . PRO A 1 641 ? 57.284 81.472 -43.331 1.00 19.55 ? 641 PRO A O 1 ATOM 5294 C CB . PRO A 1 641 ? 59.161 81.912 -40.946 1.00 19.76 ? 641 PRO A CB 1 ATOM 5295 C CG . PRO A 1 641 ? 58.876 83.006 -40.019 1.00 19.56 ? 641 PRO A CG 1 ATOM 5296 C CD . PRO A 1 641 ? 57.882 83.872 -40.719 1.00 20.59 ? 641 PRO A CD 1 ATOM 5297 N N . GLU A 1 642 ? 59.314 80.869 -44.051 1.00 19.26 ? 642 GLU A N 1 ATOM 5298 C CA . GLU A 1 642 ? 58.796 79.904 -45.012 1.00 19.45 ? 642 GLU A CA 1 ATOM 5299 C C . GLU A 1 642 ? 57.828 78.867 -44.437 1.00 18.32 ? 642 GLU A C 1 ATOM 5300 O O . GLU A 1 642 ? 56.870 78.467 -45.099 1.00 18.62 ? 642 GLU A O 1 ATOM 5301 C CB . GLU A 1 642 ? 59.964 79.176 -45.688 1.00 20.56 ? 642 GLU A CB 1 ATOM 5302 C CG . GLU A 1 642 ? 59.537 78.153 -46.715 1.00 22.15 ? 642 GLU A CG 1 ATOM 5303 C CD . GLU A 1 642 ? 60.704 77.582 -47.513 1.00 23.40 ? 642 GLU A CD 1 ATOM 5304 O OE1 . GLU A 1 642 ? 61.878 77.925 -47.236 1.00 29.17 ? 642 GLU A OE1 1 ATOM 5305 O OE2 . GLU A 1 642 ? 60.441 76.778 -48.426 1.00 30.33 ? 642 GLU A OE2 1 ATOM 5306 N N . HIS A 1 643 ? 58.101 78.409 -43.215 1.00 16.32 ? 643 HIS A N 1 ATOM 5307 C CA . HIS A 1 643 ? 57.334 77.272 -42.658 1.00 15.42 ? 643 HIS A CA 1 ATOM 5308 C C . HIS A 1 643 ? 56.363 77.673 -41.554 1.00 14.24 ? 643 HIS A C 1 ATOM 5309 O O . HIS A 1 643 ? 55.890 76.817 -40.799 1.00 13.32 ? 643 HIS A O 1 ATOM 5310 C CB . HIS A 1 643 ? 58.279 76.169 -42.172 1.00 15.94 ? 643 HIS A CB 1 ATOM 5311 C CG . HIS A 1 643 ? 59.114 75.601 -43.269 1.00 18.14 ? 643 HIS A CG 1 ATOM 5312 N ND1 . HIS A 1 643 ? 58.650 74.625 -44.119 1.00 23.84 ? 643 HIS A ND1 1 ATOM 5313 C CD2 . HIS A 1 643 ? 60.370 75.900 -43.674 1.00 21.31 ? 643 HIS A CD2 1 ATOM 5314 C CE1 . HIS A 1 643 ? 59.592 74.336 -45.001 1.00 22.89 ? 643 HIS A CE1 1 ATOM 5315 N NE2 . HIS A 1 643 ? 60.645 75.096 -44.751 1.00 22.57 ? 643 HIS A NE2 1 ATOM 5316 N N . THR A 1 644 ? 56.037 78.955 -41.493 1.00 12.44 ? 644 THR A N 1 ATOM 5317 C CA . THR A 1 644 ? 55.071 79.462 -40.524 1.00 12.66 ? 644 THR A CA 1 ATOM 5318 C C . THR A 1 644 ? 53.908 80.072 -41.291 1.00 12.63 ? 644 THR A C 1 ATOM 5319 O O . THR A 1 644 ? 54.134 80.895 -42.213 1.00 13.06 ? 644 THR A O 1 ATOM 5320 C CB . THR A 1 644 ? 55.750 80.473 -39.586 1.00 12.08 ? 644 THR A CB 1 ATOM 5321 O OG1 . THR A 1 644 ? 56.764 79.783 -38.841 1.00 12.41 ? 644 THR A OG1 1 ATOM 5322 C CG2 . THR A 1 644 ? 54.776 81.035 -38.506 1.00 13.63 ? 644 THR A CG2 1 ATOM 5323 N N . SER A 1 645 ? 52.682 79.654 -40.964 1.00 11.30 ? 645 SER A N 1 ATOM 5324 C CA . SER A 1 645 ? 51.464 80.252 -41.528 1.00 11.34 ? 645 SER A CA 1 ATOM 5325 C C . SER A 1 645 ? 50.770 81.104 -40.479 1.00 10.71 ? 645 SER A C 1 ATOM 5326 O O . SER A 1 645 ? 51.088 81.027 -39.288 1.00 10.68 ? 645 SER A O 1 ATOM 5327 C CB . SER A 1 645 ? 50.491 79.210 -42.050 1.00 12.14 ? 645 SER A CB 1 ATOM 5328 O OG . SER A 1 645 ? 49.987 78.423 -40.974 1.00 15.65 ? 645 SER A OG 1 ATOM 5329 N N . TYR A 1 646 ? 49.836 81.930 -40.926 1.00 11.00 ? 646 TYR A N 1 ATOM 5330 C CA . TYR A 1 646 ? 49.129 82.865 -40.064 1.00 10.86 ? 646 TYR A CA 1 ATOM 5331 C C . TYR A 1 646 ? 47.648 82.607 -40.147 1.00 11.36 ? 646 TYR A C 1 ATOM 5332 O O . TYR A 1 646 ? 47.083 82.500 -41.227 1.00 13.56 ? 646 TYR A O 1 ATOM 5333 C CB . TYR A 1 646 ? 49.454 84.299 -40.488 1.00 12.16 ? 646 TYR A CB 1 ATOM 5334 C CG . TYR A 1 646 ? 50.910 84.519 -40.253 1.00 11.21 ? 646 TYR A CG 1 ATOM 5335 C CD1 . TYR A 1 646 ? 51.371 84.924 -39.002 1.00 9.76 ? 646 TYR A CD1 1 ATOM 5336 C CD2 . TYR A 1 646 ? 51.847 84.179 -41.223 1.00 12.85 ? 646 TYR A CD2 1 ATOM 5337 C CE1 . TYR A 1 646 ? 52.729 85.067 -38.751 1.00 12.23 ? 646 TYR A CE1 1 ATOM 5338 C CE2 . TYR A 1 646 ? 53.208 84.310 -40.983 1.00 14.35 ? 646 TYR A CE2 1 ATOM 5339 C CZ . TYR A 1 646 ? 53.646 84.758 -39.744 1.00 13.09 ? 646 TYR A CZ 1 ATOM 5340 O OH . TYR A 1 646 ? 54.991 84.877 -39.454 1.00 13.88 ? 646 TYR A OH 1 ATOM 5341 N N . ALA A 1 647 ? 47.009 82.513 -38.976 1.00 10.00 ? 647 ALA A N 1 ATOM 5342 C CA . ALA A 1 647 ? 45.570 82.323 -38.923 1.00 10.27 ? 647 ALA A CA 1 ATOM 5343 C C . ALA A 1 647 ? 44.808 83.550 -39.425 1.00 10.04 ? 647 ALA A C 1 ATOM 5344 O O . ALA A 1 647 ? 45.217 84.677 -39.200 1.00 10.62 ? 647 ALA A O 1 ATOM 5345 C CB . ALA A 1 647 ? 45.135 82.018 -37.481 1.00 11.15 ? 647 ALA A CB 1 ATOM 5346 N N . SER A 1 648 ? 43.673 83.299 -40.048 1.00 10.65 ? 648 SER A N 1 ATOM 5347 C CA . SER A 1 648 ? 42.737 84.389 -40.308 1.00 10.98 ? 648 SER A CA 1 ATOM 5348 C C . SER A 1 648 ? 41.818 84.535 -39.097 1.00 9.17 ? 648 SER A C 1 ATOM 5349 O O . SER A 1 648 ? 41.647 83.571 -38.284 1.00 8.83 ? 648 SER A O 1 ATOM 5350 C CB . SER A 1 648 ? 41.923 84.089 -41.553 1.00 12.62 ? 648 SER A CB 1 ATOM 5351 O OG . SER A 1 648 ? 41.132 82.944 -41.384 1.00 17.44 ? 648 SER A OG 1 ATOM 5352 N N . ASN A 1 649 ? 41.235 85.704 -38.914 1.00 8.89 ? 649 ASN A N 1 ATOM 5353 C CA . ASN A 1 649 ? 40.356 85.994 -37.783 1.00 8.48 ? 649 ASN A CA 1 ATOM 5354 C C . ASN A 1 649 ? 39.142 86.725 -38.247 1.00 9.79 ? 649 ASN A C 1 ATOM 5355 O O . ASN A 1 649 ? 39.260 87.675 -39.036 1.00 9.70 ? 649 ASN A O 1 ATOM 5356 C CB . ASN A 1 649 ? 41.067 86.812 -36.705 1.00 9.90 ? 649 ASN A CB 1 ATOM 5357 C CG . ASN A 1 649 ? 42.273 86.087 -36.152 1.00 10.24 ? 649 ASN A CG 1 ATOM 5358 O OD1 . ASN A 1 649 ? 42.137 85.322 -35.182 1.00 12.12 ? 649 ASN A OD1 1 ATOM 5359 N ND2 . ASN A 1 649 ? 43.437 86.274 -36.763 1.00 11.95 ? 649 ASN A ND2 1 ATOM 5360 N N . LEU A 1 650 ? 37.988 86.292 -37.776 1.00 8.36 ? 650 LEU A N 1 ATOM 5361 C CA . LEU A 1 650 ? 36.720 86.880 -38.155 1.00 9.52 ? 650 LEU A CA 1 ATOM 5362 C C . LEU A 1 650 ? 35.932 87.141 -36.892 1.00 10.51 ? 650 LEU A C 1 ATOM 5363 O O . LEU A 1 650 ? 35.668 86.229 -36.100 1.00 10.71 ? 650 LEU A O 1 ATOM 5364 C CB . LEU A 1 650 ? 35.952 85.926 -39.074 1.00 10.14 ? 650 LEU A CB 1 ATOM 5365 C CG . LEU A 1 650 ? 34.504 86.248 -39.382 1.00 10.74 ? 650 LEU A CG 1 ATOM 5366 C CD1 . LEU A 1 650 ? 34.435 87.528 -40.251 1.00 12.01 ? 650 LEU A CD1 1 ATOM 5367 C CD2 . LEU A 1 650 ? 33.915 85.089 -40.157 1.00 13.27 ? 650 LEU A CD2 1 ATOM 5368 N N . LEU A 1 651 ? 35.563 88.382 -36.669 1.00 10.40 ? 651 LEU A N 1 ATOM 5369 C CA . LEU A 1 651 ? 34.771 88.778 -35.525 1.00 11.84 ? 651 LEU A CA 1 ATOM 5370 C C . LEU A 1 651 ? 33.329 89.014 -35.958 1.00 12.35 ? 651 LEU A C 1 ATOM 5371 O O . LEU A 1 651 ? 33.051 89.880 -36.806 1.00 12.51 ? 651 LEU A O 1 ATOM 5372 C CB . LEU A 1 651 ? 35.366 90.042 -34.923 1.00 12.90 ? 651 LEU A CB 1 ATOM 5373 C CG . LEU A 1 651 ? 35.069 90.392 -33.449 1.00 17.88 ? 651 LEU A CG 1 ATOM 5374 C CD1 . LEU A 1 651 ? 33.799 91.155 -33.319 1.00 24.33 ? 651 LEU A CD1 1 ATOM 5375 C CD2 . LEU A 1 651 ? 35.089 89.224 -32.475 1.00 17.66 ? 651 LEU A CD2 1 ATOM 5376 N N . LEU A 1 652 ? 32.407 88.213 -35.449 1.00 11.85 ? 652 LEU A N 1 ATOM 5377 C CA . LEU A 1 652 ? 31.009 88.303 -35.797 1.00 12.45 ? 652 LEU A CA 1 ATOM 5378 C C . LEU A 1 652 ? 30.243 89.015 -34.694 1.00 13.73 ? 652 LEU A C 1 ATOM 5379 O O . LEU A 1 652 ? 30.137 88.540 -33.567 1.00 13.94 ? 652 LEU A O 1 ATOM 5380 C CB . LEU A 1 652 ? 30.429 86.920 -36.080 1.00 12.34 ? 652 LEU A CB 1 ATOM 5381 C CG . LEU A 1 652 ? 31.147 86.176 -37.201 1.00 11.14 ? 652 LEU A CG 1 ATOM 5382 C CD1 . LEU A 1 652 ? 30.615 84.775 -37.332 1.00 12.36 ? 652 LEU A CD1 1 ATOM 5383 C CD2 . LEU A 1 652 ? 30.964 86.931 -38.523 1.00 13.52 ? 652 LEU A CD2 1 ATOM 5384 N N . ARG A 1 653 ? 29.733 90.187 -35.037 1.00 14.36 ? 653 ARG A N 1 ATOM 5385 C CA . ARG A 1 653 ? 28.963 90.989 -34.124 1.00 16.59 ? 653 ARG A CA 1 ATOM 5386 C C . ARG A 1 653 ? 28.384 92.150 -34.927 1.00 17.09 ? 653 ARG A C 1 ATOM 5387 O O . ARG A 1 653 ? 28.947 92.576 -35.897 1.00 17.96 ? 653 ARG A O 1 ATOM 5388 C CB . ARG A 1 653 ? 29.840 91.539 -33.009 1.00 17.04 ? 653 ARG A CB 1 ATOM 5389 C CG . ARG A 1 653 ? 30.435 92.845 -33.395 1.00 21.02 ? 653 ARG A CG 1 ATOM 5390 C CD . ARG A 1 653 ? 31.284 93.457 -32.347 1.00 27.92 ? 653 ARG A CD 1 ATOM 5391 N NE . ARG A 1 653 ? 30.667 93.569 -31.045 1.00 30.56 ? 653 ARG A NE 1 ATOM 5392 C CZ . ARG A 1 653 ? 30.987 94.419 -30.091 1.00 32.91 ? 653 ARG A CZ 1 ATOM 5393 N NH1 . ARG A 1 653 ? 31.915 95.362 -30.286 1.00 34.95 ? 653 ARG A NH1 1 ATOM 5394 N NH2 . ARG A 1 653 ? 30.348 94.368 -28.936 1.00 36.22 ? 653 ARG A NH2 1 ATOM 5395 N N . LYS A 1 654 ? 27.262 92.663 -34.483 1.00 18.92 ? 654 LYS A N 1 ATOM 5396 C CA . LYS A 1 654 ? 26.794 93.903 -35.077 1.00 20.97 ? 654 LYS A CA 1 ATOM 5397 C C . LYS A 1 654 ? 27.559 95.057 -34.423 1.00 21.66 ? 654 LYS A C 1 ATOM 5398 O O . LYS A 1 654 ? 28.047 94.926 -33.303 1.00 21.97 ? 654 LYS A O 1 ATOM 5399 C CB . LYS A 1 654 ? 25.273 94.026 -34.942 1.00 21.89 ? 654 LYS A CB 1 ATOM 5400 C CG . LYS A 1 654 ? 24.511 92.998 -35.791 1.00 24.72 ? 654 LYS A CG 1 ATOM 5401 C CD . LYS A 1 654 ? 23.267 93.587 -36.465 1.00 30.99 ? 654 LYS A CD 1 ATOM 5402 C CE . LYS A 1 654 ? 23.644 94.439 -37.693 1.00 33.39 ? 654 LYS A CE 1 ATOM 5403 N NZ . LYS A 1 654 ? 22.505 94.658 -38.642 1.00 35.47 ? 654 LYS A NZ 1 ATOM 5404 N N . ASN A 1 655 ? 27.689 96.168 -35.132 1.00 22.96 ? 655 ASN A N 1 ATOM 5405 C CA . ASN A 1 655 ? 28.385 97.329 -34.581 1.00 23.49 ? 655 ASN A CA 1 ATOM 5406 C C . ASN A 1 655 ? 29.838 97.003 -34.195 1.00 22.41 ? 655 ASN A C 1 ATOM 5407 O O . ASN A 1 655 ? 30.257 97.252 -33.061 1.00 22.62 ? 655 ASN A O 1 ATOM 5408 C CB . ASN A 1 655 ? 27.619 97.854 -33.351 1.00 24.79 ? 655 ASN A CB 1 ATOM 5409 C CG . ASN A 1 655 ? 27.980 99.279 -32.992 1.00 28.54 ? 655 ASN A CG 1 ATOM 5410 O OD1 . ASN A 1 655 ? 28.352 100.075 -33.860 1.00 32.39 ? 655 ASN A OD1 1 ATOM 5411 N ND2 . ASN A 1 655 ? 27.865 99.616 -31.700 1.00 31.24 ? 655 ASN A ND2 1 ATOM 5412 N N . PRO A 1 656 ? 30.620 96.452 -35.119 1.00 20.96 ? 656 PRO A N 1 ATOM 5413 C CA . PRO A 1 656 ? 32.003 96.130 -34.775 1.00 19.46 ? 656 PRO A CA 1 ATOM 5414 C C . PRO A 1 656 ? 32.823 97.400 -34.710 1.00 18.18 ? 656 PRO A C 1 ATOM 5415 O O . PRO A 1 656 ? 32.487 98.407 -35.357 1.00 17.57 ? 656 PRO A O 1 ATOM 5416 C CB . PRO A 1 656 ? 32.477 95.291 -35.950 1.00 19.11 ? 656 PRO A CB 1 ATOM 5417 C CG . PRO A 1 656 ? 31.657 95.769 -37.082 1.00 19.56 ? 656 PRO A CG 1 ATOM 5418 C CD . PRO A 1 656 ? 30.297 96.078 -36.510 1.00 21.00 ? 656 PRO A CD 1 ATOM 5419 N N . THR A 1 657 ? 33.873 97.337 -33.914 1.00 17.96 ? 657 THR A N 1 ATOM 5420 C CA . THR A 1 657 ? 34.932 98.324 -33.974 1.00 17.94 ? 657 THR A CA 1 ATOM 5421 C C . THR A 1 657 ? 36.217 97.606 -34.376 1.00 16.88 ? 657 THR A C 1 ATOM 5422 O O . THR A 1 657 ? 36.309 96.377 -34.290 1.00 16.11 ? 657 THR A O 1 ATOM 5423 C CB . THR A 1 657 ? 35.096 99.024 -32.634 1.00 19.28 ? 657 THR A CB 1 ATOM 5424 O OG1 . THR A 1 657 ? 35.072 98.057 -31.578 1.00 21.98 ? 657 THR A OG1 1 ATOM 5425 C CG2 . THR A 1 657 ? 33.881 99.898 -32.339 1.00 20.12 ? 657 THR A CG2 1 ATOM 5426 N N . SER A 1 658 ? 37.212 98.370 -34.797 1.00 15.23 ? 658 SER A N 1 ATOM 5427 C CA . SER A 1 658 ? 38.448 97.818 -35.332 1.00 15.30 ? 658 SER A CA 1 ATOM 5428 C C . SER A 1 658 ? 39.238 97.016 -34.288 1.00 15.67 ? 658 SER A C 1 ATOM 5429 O O . SER A 1 658 ? 39.050 97.194 -33.080 1.00 16.33 ? 658 SER A O 1 ATOM 5430 C CB . SER A 1 658 ? 39.315 98.965 -35.809 1.00 16.26 ? 658 SER A CB 1 ATOM 5431 O OG . SER A 1 658 ? 39.626 99.736 -34.672 1.00 17.94 ? 658 SER A OG 1 ATOM 5432 N N . LEU A 1 659 ? 40.104 96.128 -34.780 1.00 14.75 ? 659 LEU A N 1 ATOM 5433 C CA . LEU A 1 659 ? 40.913 95.253 -33.919 1.00 15.59 ? 659 LEU A CA 1 ATOM 5434 C C . LEU A 1 659 ? 42.329 95.190 -34.493 1.00 15.50 ? 659 LEU A C 1 ATOM 5435 O O . LEU A 1 659 ? 42.660 94.273 -35.250 1.00 15.52 ? 659 LEU A O 1 ATOM 5436 C CB . LEU A 1 659 ? 40.308 93.837 -33.858 1.00 15.83 ? 659 LEU A CB 1 ATOM 5437 C CG . LEU A 1 659 ? 39.010 93.637 -33.072 1.00 17.05 ? 659 LEU A CG 1 ATOM 5438 C CD1 . LEU A 1 659 ? 38.402 92.243 -33.363 1.00 19.39 ? 659 LEU A CD1 1 ATOM 5439 C CD2 . LEU A 1 659 ? 39.223 93.853 -31.584 1.00 17.39 ? 659 LEU A CD2 1 ATOM 5440 N N . PRO A 1 660 ? 43.142 96.217 -34.215 1.00 15.64 ? 660 PRO A N 1 ATOM 5441 C CA . PRO A 1 660 ? 44.538 96.238 -34.665 1.00 15.90 ? 660 PRO A CA 1 ATOM 5442 C C . PRO A 1 660 ? 45.353 95.131 -33.983 1.00 15.14 ? 660 PRO A C 1 ATOM 5443 O O . PRO A 1 660 ? 45.066 94.778 -32.836 1.00 14.67 ? 660 PRO A O 1 ATOM 5444 C CB . PRO A 1 660 ? 45.031 97.626 -34.240 1.00 16.42 ? 660 PRO A CB 1 ATOM 5445 C CG . PRO A 1 660 ? 44.086 98.112 -33.202 1.00 16.92 ? 660 PRO A CG 1 ATOM 5446 C CD . PRO A 1 660 ? 42.764 97.435 -33.470 1.00 16.51 ? 660 PRO A CD 1 ATOM 5447 N N . LEU A 1 661 ? 46.325 94.582 -34.697 1.00 15.76 ? 661 LEU A N 1 ATOM 5448 C CA . LEU A 1 661 ? 47.114 93.470 -34.169 1.00 16.06 ? 661 LEU A CA 1 ATOM 5449 C C . LEU A 1 661 ? 48.623 93.658 -34.365 1.00 17.35 ? 661 LEU A C 1 ATOM 5450 O O . LEU A 1 661 ? 49.370 92.689 -34.479 1.00 16.19 ? 661 LEU A O 1 ATOM 5451 C CB . LEU A 1 661 ? 46.658 92.179 -34.835 1.00 16.04 ? 661 LEU A CB 1 ATOM 5452 C CG . LEU A 1 661 ? 45.250 91.661 -34.505 1.00 14.34 ? 661 LEU A CG 1 ATOM 5453 C CD1 . LEU A 1 661 ? 45.001 90.392 -35.316 1.00 13.65 ? 661 LEU A CD1 1 ATOM 5454 C CD2 . LEU A 1 661 ? 45.072 91.398 -33.008 1.00 14.15 ? 661 LEU A CD2 1 ATOM 5455 N N . GLY A 1 662 ? 49.075 94.910 -34.414 1.00 18.12 ? 662 GLY A N 1 ATOM 5456 C CA . GLY A 1 662 ? 50.505 95.183 -34.531 1.00 18.70 ? 662 GLY A CA 1 ATOM 5457 C C . GLY A 1 662 ? 51.066 94.654 -35.830 1.00 19.39 ? 662 GLY A C 1 ATOM 5458 O O . GLY A 1 662 ? 50.474 94.867 -36.887 1.00 19.32 ? 662 GLY A O 1 ATOM 5459 N N . GLN A 1 663 ? 52.180 93.915 -35.756 1.00 19.31 ? 663 GLN A N 1 ATOM 5460 C CA . GLN A 1 663 ? 52.819 93.399 -36.976 1.00 19.95 ? 663 GLN A CA 1 ATOM 5461 C C . GLN A 1 663 ? 52.170 92.138 -37.530 1.00 18.25 ? 663 GLN A C 1 ATOM 5462 O O . GLN A 1 663 ? 52.625 91.611 -38.540 1.00 19.27 ? 663 GLN A O 1 ATOM 5463 C CB . GLN A 1 663 ? 54.325 93.122 -36.806 1.00 20.89 ? 663 GLN A CB 1 ATOM 5464 C CG . GLN A 1 663 ? 55.123 94.044 -35.898 1.00 24.61 ? 663 GLN A CG 1 ATOM 5465 C CD . GLN A 1 663 ? 56.279 93.272 -35.240 1.00 28.13 ? 663 GLN A CD 1 ATOM 5466 O OE1 . GLN A 1 663 ? 57.183 92.808 -35.938 1.00 28.41 ? 663 GLN A OE1 1 ATOM 5467 N NE2 . GLN A 1 663 ? 56.220 93.095 -33.917 1.00 30.57 ? 663 GLN A NE2 1 ATOM 5468 N N . TYR A 1 664 ? 51.097 91.670 -36.896 1.00 18.52 ? 664 TYR A N 1 ATOM 5469 C CA . TYR A 1 664 ? 50.404 90.471 -37.376 1.00 17.39 ? 664 TYR A CA 1 ATOM 5470 C C . TYR A 1 664 ? 49.984 90.654 -38.829 1.00 17.69 ? 664 TYR A C 1 ATOM 5471 O O . TYR A 1 664 ? 49.319 91.647 -39.146 1.00 19.02 ? 664 TYR A O 1 ATOM 5472 C CB . TYR A 1 664 ? 49.190 90.200 -36.497 1.00 15.86 ? 664 TYR A CB 1 ATOM 5473 C CG . TYR A 1 664 ? 48.593 88.828 -36.732 1.00 13.93 ? 664 TYR A CG 1 ATOM 5474 C CD1 . TYR A 1 664 ? 49.173 87.688 -36.170 1.00 12.98 ? 664 TYR A CD1 1 ATOM 5475 C CD2 . TYR A 1 664 ? 47.436 88.677 -37.483 1.00 13.23 ? 664 TYR A CD2 1 ATOM 5476 C CE1 . TYR A 1 664 ? 48.641 86.436 -36.394 1.00 12.24 ? 664 TYR A CE1 1 ATOM 5477 C CE2 . TYR A 1 664 ? 46.891 87.405 -37.728 1.00 12.14 ? 664 TYR A CE2 1 ATOM 5478 C CZ . TYR A 1 664 ? 47.495 86.290 -37.149 1.00 11.71 ? 664 TYR A CZ 1 ATOM 5479 O OH . TYR A 1 664 ? 46.906 85.067 -37.359 1.00 13.42 ? 664 TYR A OH 1 ATOM 5480 N N . PRO A 1 665 ? 50.391 89.760 -39.732 1.00 18.66 ? 665 PRO A N 1 ATOM 5481 C CA . PRO A 1 665 ? 50.233 90.033 -41.175 1.00 19.40 ? 665 PRO A CA 1 ATOM 5482 C C . PRO A 1 665 ? 48.835 89.983 -41.793 1.00 20.31 ? 665 PRO A C 1 ATOM 5483 O O . PRO A 1 665 ? 48.684 90.440 -42.930 1.00 21.59 ? 665 PRO A O 1 ATOM 5484 C CB . PRO A 1 665 ? 51.162 89.014 -41.844 1.00 19.51 ? 665 PRO A CB 1 ATOM 5485 C CG . PRO A 1 665 ? 51.309 87.919 -40.845 1.00 19.35 ? 665 PRO A CG 1 ATOM 5486 C CD . PRO A 1 665 ? 51.133 88.512 -39.482 1.00 17.95 ? 665 PRO A CD 1 ATOM 5487 N N . GLU A 1 666 ? 47.844 89.429 -41.094 1.00 20.27 ? 666 GLU A N 1 ATOM 5488 C CA . GLU A 1 666 ? 46.490 89.309 -41.647 1.00 19.29 ? 666 GLU A CA 1 ATOM 5489 C C . GLU A 1 666 ? 45.580 90.239 -40.878 1.00 18.56 ? 666 GLU A C 1 ATOM 5490 O O . GLU A 1 666 ? 45.549 90.194 -39.648 1.00 18.27 ? 666 GLU A O 1 ATOM 5491 C CB . GLU A 1 666 ? 45.963 87.877 -41.502 1.00 20.81 ? 666 GLU A CB 1 ATOM 5492 C CG . GLU A 1 666 ? 46.674 86.849 -42.361 1.00 25.49 ? 666 GLU A CG 1 ATOM 5493 C CD . GLU A 1 666 ? 46.624 87.203 -43.832 1.00 30.37 ? 666 GLU A CD 1 ATOM 5494 O OE1 . GLU A 1 666 ? 45.508 87.412 -44.354 1.00 33.57 ? 666 GLU A OE1 1 ATOM 5495 O OE2 . GLU A 1 666 ? 47.703 87.290 -44.459 1.00 34.35 ? 666 GLU A OE2 1 ATOM 5496 N N . ASP A 1 667 ? 44.826 91.075 -41.597 1.00 16.26 ? 667 ASP A N 1 ATOM 5497 C CA . ASP A 1 667 ? 43.873 91.964 -40.943 1.00 15.78 ? 667 ASP A CA 1 ATOM 5498 C C . ASP A 1 667 ? 42.637 91.177 -40.460 1.00 12.73 ? 667 ASP A C 1 ATOM 5499 O O . ASP A 1 667 ? 42.123 90.338 -41.193 1.00 12.51 ? 667 ASP A O 1 ATOM 5500 C CB . ASP A 1 667 ? 43.360 93.013 -41.938 1.00 17.51 ? 667 ASP A CB 1 ATOM 5501 C CG . ASP A 1 667 ? 44.405 94.033 -42.304 1.00 21.79 ? 667 ASP A CG 1 ATOM 5502 O OD1 . ASP A 1 667 ? 45.296 94.314 -41.463 1.00 26.40 ? 667 ASP A OD1 1 ATOM 5503 O OD2 . ASP A 1 667 ? 44.375 94.649 -43.395 1.00 26.87 ? 667 ASP A OD2 1 ATOM 5504 N N . VAL A 1 668 ? 42.147 91.511 -39.282 1.00 11.54 ? 668 VAL A N 1 ATOM 5505 C CA . VAL A 1 668 ? 40.872 90.941 -38.768 1.00 11.35 ? 668 VAL A CA 1 ATOM 5506 C C . VAL A 1 668 ? 39.739 91.344 -39.688 1.00 11.73 ? 668 VAL A C 1 ATOM 5507 O O . VAL A 1 668 ? 39.676 92.513 -40.144 1.00 12.43 ? 668 VAL A O 1 ATOM 5508 C CB . VAL A 1 668 ? 40.549 91.376 -37.337 1.00 12.18 ? 668 VAL A CB 1 ATOM 5509 C CG1 . VAL A 1 668 ? 39.211 90.797 -36.850 1.00 11.77 ? 668 VAL A CG1 1 ATOM 5510 C CG2 . VAL A 1 668 ? 41.679 90.936 -36.405 1.00 13.33 ? 668 VAL A CG2 1 ATOM 5511 N N . LYS A 1 669 ? 38.894 90.372 -39.997 1.00 9.88 ? 669 LYS A N 1 ATOM 5512 C CA . LYS A 1 669 ? 37.648 90.563 -40.758 1.00 11.58 ? 669 LYS A CA 1 ATOM 5513 C C . LYS A 1 669 ? 36.440 90.635 -39.836 1.00 11.39 ? 669 LYS A C 1 ATOM 5514 O O . LYS A 1 669 ? 36.455 90.075 -38.721 1.00 11.01 ? 669 LYS A O 1 ATOM 5515 C CB . LYS A 1 669 ? 37.458 89.419 -41.755 1.00 13.05 ? 669 LYS A CB 1 ATOM 5516 C CG . LYS A 1 669 ? 38.200 89.575 -43.067 1.00 19.73 ? 669 LYS A CG 1 ATOM 5517 C CD . LYS A 1 669 ? 39.686 89.358 -42.974 1.00 26.92 ? 669 LYS A CD 1 ATOM 5518 C CE . LYS A 1 669 ? 40.395 90.061 -44.141 1.00 28.93 ? 669 LYS A CE 1 ATOM 5519 N NZ . LYS A 1 669 ? 41.802 90.423 -43.772 1.00 31.05 ? 669 LYS A NZ 1 ATOM 5520 N N . PHE A 1 670 ? 35.389 91.300 -40.304 1.00 10.74 ? 670 PHE A N 1 ATOM 5521 C CA . PHE A 1 670 ? 34.170 91.521 -39.521 1.00 11.56 ? 670 PHE A CA 1 ATOM 5522 C C . PHE A 1 670 ? 32.940 91.095 -40.281 1.00 13.17 ? 670 PHE A C 1 ATOM 5523 O O . PHE A 1 670 ? 32.946 91.071 -41.493 1.00 13.28 ? 670 PHE A O 1 ATOM 5524 C CB . PHE A 1 670 ? 34.028 92.991 -39.085 1.00 12.13 ? 670 PHE A CB 1 ATOM 5525 C CG . PHE A 1 670 ? 35.196 93.476 -38.317 1.00 12.09 ? 670 PHE A CG 1 ATOM 5526 C CD1 . PHE A 1 670 ? 36.307 94.005 -38.983 1.00 14.09 ? 670 PHE A CD1 1 ATOM 5527 C CD2 . PHE A 1 670 ? 35.231 93.345 -36.925 1.00 15.64 ? 670 PHE A CD2 1 ATOM 5528 C CE1 . PHE A 1 670 ? 37.427 94.421 -38.275 1.00 14.50 ? 670 PHE A CE1 1 ATOM 5529 C CE2 . PHE A 1 670 ? 36.343 93.764 -36.212 1.00 16.30 ? 670 PHE A CE2 1 ATOM 5530 C CZ . PHE A 1 670 ? 37.438 94.296 -36.888 1.00 14.85 ? 670 PHE A CZ 1 ATOM 5531 N N . GLY A 1 671 ? 31.883 90.744 -39.559 1.00 13.15 ? 671 GLY A N 1 ATOM 5532 C CA . GLY A 1 671 ? 30.646 90.317 -40.189 1.00 13.27 ? 671 GLY A CA 1 ATOM 5533 C C . GLY A 1 671 ? 29.532 90.331 -39.166 1.00 13.53 ? 671 GLY A C 1 ATOM 5534 O O . GLY A 1 671 ? 29.784 90.335 -37.959 1.00 12.11 ? 671 GLY A O 1 ATOM 5535 N N . ASP A 1 672 ? 28.286 90.378 -39.633 1.00 14.29 ? 672 ASP A N 1 ATOM 5536 C CA . ASP A 1 672 ? 27.161 90.174 -38.739 1.00 15.61 ? 672 ASP A CA 1 ATOM 5537 C C . ASP A 1 672 ? 27.156 88.693 -38.330 1.00 15.12 ? 672 ASP A C 1 ATOM 5538 O O . ASP A 1 672 ? 27.622 87.851 -39.090 1.00 14.37 ? 672 ASP A O 1 ATOM 5539 C CB . ASP A 1 672 ? 25.849 90.454 -39.471 1.00 17.02 ? 672 ASP A CB 1 ATOM 5540 C CG . ASP A 1 672 ? 25.562 91.937 -39.636 1.00 20.80 ? 672 ASP A CG 1 ATOM 5541 O OD1 . ASP A 1 672 ? 26.252 92.772 -39.026 1.00 24.20 ? 672 ASP A OD1 1 ATOM 5542 O OD2 . ASP A 1 672 ? 24.623 92.350 -40.370 1.00 27.67 ? 672 ASP A OD2 1 ATOM 5543 N N . PRO A 1 673 ? 26.586 88.391 -37.155 1.00 15.15 ? 673 PRO A N 1 ATOM 5544 C CA . PRO A 1 673 ? 26.442 86.997 -36.720 1.00 15.41 ? 673 PRO A CA 1 ATOM 5545 C C . PRO A 1 673 ? 25.844 86.117 -37.815 1.00 15.20 ? 673 PRO A C 1 ATOM 5546 O O . PRO A 1 673 ? 24.914 86.512 -38.526 1.00 14.88 ? 673 PRO A O 1 ATOM 5547 C CB . PRO A 1 673 ? 25.495 87.111 -35.537 1.00 15.77 ? 673 PRO A CB 1 ATOM 5548 C CG . PRO A 1 673 ? 25.778 88.452 -34.963 1.00 17.12 ? 673 PRO A CG 1 ATOM 5549 C CD . PRO A 1 673 ? 26.043 89.334 -36.159 1.00 15.75 ? 673 PRO A CD 1 ATOM 5550 N N . ARG A 1 674 ? 26.392 84.923 -37.961 1.00 13.86 ? 674 ARG A N 1 ATOM 5551 C CA . ARG A 1 674 ? 25.952 83.991 -38.990 1.00 14.62 ? 674 ARG A CA 1 ATOM 5552 C C . ARG A 1 674 ? 26.403 82.585 -38.627 1.00 13.96 ? 674 ARG A C 1 ATOM 5553 O O . ARG A 1 674 ? 27.352 82.413 -37.867 1.00 14.28 ? 674 ARG A O 1 ATOM 5554 C CB . ARG A 1 674 ? 26.518 84.388 -40.363 1.00 14.32 ? 674 ARG A CB 1 ATOM 5555 C CG . ARG A 1 674 ? 28.012 84.317 -40.547 1.00 15.71 ? 674 ARG A CG 1 ATOM 5556 C CD . ARG A 1 674 ? 28.351 84.442 -42.049 1.00 16.63 ? 674 ARG A CD 1 ATOM 5557 N NE . ARG A 1 674 ? 29.714 84.111 -42.435 1.00 19.91 ? 674 ARG A NE 1 ATOM 5558 C CZ . ARG A 1 674 ? 30.697 84.989 -42.577 1.00 21.04 ? 674 ARG A CZ 1 ATOM 5559 N NH1 . ARG A 1 674 ? 30.494 86.289 -42.331 1.00 22.91 ? 674 ARG A NH1 1 ATOM 5560 N NH2 . ARG A 1 674 ? 31.901 84.561 -42.966 1.00 22.21 ? 674 ARG A NH2 1 ATOM 5561 N N . GLU A 1 675 ? 25.723 81.589 -39.165 1.00 13.86 ? 675 GLU A N 1 ATOM 5562 C CA . GLU A 1 675 ? 26.188 80.217 -39.040 1.00 14.04 ? 675 GLU A CA 1 ATOM 5563 C C . GLU A 1 675 ? 27.509 80.041 -39.760 1.00 14.73 ? 675 GLU A C 1 ATOM 5564 O O . GLU A 1 675 ? 27.767 80.664 -40.801 1.00 16.43 ? 675 GLU A O 1 ATOM 5565 C CB . GLU A 1 675 ? 25.114 79.241 -39.533 1.00 15.17 ? 675 GLU A CB 1 ATOM 5566 C CG . GLU A 1 675 ? 23.858 79.379 -38.707 1.00 18.36 ? 675 GLU A CG 1 ATOM 5567 C CD . GLU A 1 675 ? 23.068 78.092 -38.626 1.00 26.48 ? 675 GLU A CD 1 ATOM 5568 O OE1 . GLU A 1 675 ? 23.271 77.215 -39.519 1.00 28.59 ? 675 GLU A OE1 1 ATOM 5569 O OE2 . GLU A 1 675 ? 22.265 77.951 -37.655 1.00 29.23 ? 675 GLU A OE2 1 ATOM 5570 N N . ILE A 1 676 ? 28.391 79.229 -39.197 1.00 14.87 ? 676 ILE A N 1 ATOM 5571 C CA . ILE A 1 676 ? 29.662 78.973 -39.851 1.00 15.41 ? 676 ILE A CA 1 ATOM 5572 C C . ILE A 1 676 ? 30.066 77.511 -39.729 1.00 14.98 ? 676 ILE A C 1 ATOM 5573 O O . ILE A 1 676 ? 29.594 76.796 -38.840 1.00 15.00 ? 676 ILE A O 1 ATOM 5574 C CB . ILE A 1 676 ? 30.796 79.830 -39.286 1.00 17.40 ? 676 ILE A CB 1 ATOM 5575 C CG1 . ILE A 1 676 ? 30.953 79.590 -37.807 1.00 17.05 ? 676 ILE A CG1 1 ATOM 5576 C CG2 . ILE A 1 676 ? 30.670 81.363 -39.649 1.00 20.28 ? 676 ILE A CG2 1 ATOM 5577 C CD1 . ILE A 1 676 ? 32.383 79.668 -37.359 1.00 22.72 ? 676 ILE A CD1 1 ATOM 5578 N N . SER A 1 677 ? 30.950 77.091 -40.619 1.00 13.83 ? 677 SER A N 1 ATOM 5579 C CA A SER A 1 677 ? 31.476 75.734 -40.649 0.50 14.67 ? 677 SER A CA 1 ATOM 5580 C CA B SER A 1 677 ? 31.500 75.749 -40.553 0.50 14.55 ? 677 SER A CA 1 ATOM 5581 C C . SER A 1 677 ? 32.995 75.778 -40.690 1.00 14.23 ? 677 SER A C 1 ATOM 5582 O O . SER A 1 677 ? 33.560 76.639 -41.354 1.00 14.97 ? 677 SER A O 1 ATOM 5583 C CB A SER A 1 677 ? 30.944 75.003 -41.890 0.50 14.87 ? 677 SER A CB 1 ATOM 5584 C CB B SER A 1 677 ? 30.892 74.842 -41.619 0.50 14.49 ? 677 SER A CB 1 ATOM 5585 O OG A SER A 1 677 ? 31.292 73.635 -41.871 0.50 17.95 ? 677 SER A OG 1 ATOM 5586 O OG B SER A 1 677 ? 29.511 74.683 -41.391 0.50 17.61 ? 677 SER A OG 1 ATOM 5587 N N . LEU A 1 678 ? 33.652 74.829 -40.029 1.00 13.07 ? 678 LEU A N 1 ATOM 5588 C CA . LEU A 1 678 ? 35.092 74.752 -40.044 1.00 12.73 ? 678 LEU A CA 1 ATOM 5589 C C . LEU A 1 678 ? 35.535 73.306 -40.145 1.00 12.85 ? 678 LEU A C 1 ATOM 5590 O O . LEU A 1 678 ? 34.861 72.425 -39.601 1.00 12.33 ? 678 LEU A O 1 ATOM 5591 C CB . LEU A 1 678 ? 35.643 75.284 -38.729 1.00 13.41 ? 678 LEU A CB 1 ATOM 5592 C CG . LEU A 1 678 ? 35.690 76.778 -38.467 1.00 13.49 ? 678 LEU A CG 1 ATOM 5593 C CD1 . LEU A 1 678 ? 35.983 76.982 -36.995 1.00 16.36 ? 678 LEU A CD1 1 ATOM 5594 C CD2 . LEU A 1 678 ? 36.805 77.413 -39.297 1.00 17.83 ? 678 LEU A CD2 1 ATOM 5595 N N . ARG A 1 679 ? 36.656 73.087 -40.812 1.00 12.82 ? 679 ARG A N 1 ATOM 5596 C CA . ARG A 1 679 ? 37.293 71.777 -40.858 1.00 14.99 ? 679 ARG A CA 1 ATOM 5597 C C . ARG A 1 679 ? 38.799 71.967 -40.798 1.00 14.74 ? 679 ARG A C 1 ATOM 5598 O O . ARG A 1 679 ? 39.357 72.766 -41.566 1.00 15.02 ? 679 ARG A O 1 ATOM 5599 C CB . ARG A 1 679 ? 36.899 71.029 -42.143 1.00 15.30 ? 679 ARG A CB 1 ATOM 5600 C CG . ARG A 1 679 ? 37.533 69.649 -42.243 1.00 17.09 ? 679 ARG A CG 1 ATOM 5601 C CD . ARG A 1 679 ? 37.276 68.943 -43.581 1.00 18.80 ? 679 ARG A CD 1 ATOM 5602 N NE . ARG A 1 679 ? 37.444 67.505 -43.377 1.00 27.26 ? 679 ARG A NE 1 ATOM 5603 C CZ . ARG A 1 679 ? 37.692 66.602 -44.319 1.00 30.10 ? 679 ARG A CZ 1 ATOM 5604 N NH1 . ARG A 1 679 ? 37.827 66.952 -45.588 1.00 32.81 ? 679 ARG A NH1 1 ATOM 5605 N NH2 . ARG A 1 679 ? 37.814 65.329 -43.972 1.00 31.84 ? 679 ARG A NH2 1 ATOM 5606 N N . VAL A 1 680 ? 39.459 71.276 -39.876 1.00 13.51 ? 680 VAL A N 1 ATOM 5607 C CA . VAL A 1 680 ? 40.915 71.278 -39.799 1.00 14.18 ? 680 VAL A CA 1 ATOM 5608 C C . VAL A 1 680 ? 41.430 69.926 -40.239 1.00 16.12 ? 680 VAL A C 1 ATOM 5609 O O . VAL A 1 680 ? 40.892 68.900 -39.821 1.00 15.63 ? 680 VAL A O 1 ATOM 5610 C CB . VAL A 1 680 ? 41.426 71.576 -38.372 1.00 13.18 ? 680 VAL A CB 1 ATOM 5611 C CG1 . VAL A 1 680 ? 42.921 71.383 -38.282 1.00 14.15 ? 680 VAL A CG1 1 ATOM 5612 C CG2 . VAL A 1 680 ? 41.043 73.032 -37.967 1.00 12.27 ? 680 VAL A CG2 1 ATOM 5613 N N . GLY A 1 681 ? 42.461 69.955 -41.078 1.00 17.58 ? 681 GLY A N 1 ATOM 5614 C CA . GLY A 1 681 ? 43.048 68.735 -41.624 1.00 20.05 ? 681 GLY A CA 1 ATOM 5615 C C . GLY A 1 681 ? 41.990 67.946 -42.378 1.00 21.54 ? 681 GLY A C 1 ATOM 5616 O O . GLY A 1 681 ? 41.123 68.522 -43.059 1.00 21.97 ? 681 GLY A O 1 ATOM 5617 N N . ASN A 1 682 ? 42.055 66.628 -42.257 1.00 24.27 ? 682 ASN A N 1 ATOM 5618 C CA . ASN A 1 682 ? 41.013 65.791 -42.852 1.00 25.85 ? 682 ASN A CA 1 ATOM 5619 C C . ASN A 1 682 ? 40.089 65.315 -41.730 1.00 25.43 ? 682 ASN A C 1 ATOM 5620 O O . ASN A 1 682 ? 39.425 64.280 -41.833 1.00 26.95 ? 682 ASN A O 1 ATOM 5621 C CB . ASN A 1 682 ? 41.615 64.646 -43.678 1.00 27.27 ? 682 ASN A CB 1 ATOM 5622 C CG . ASN A 1 682 ? 42.616 63.817 -42.888 1.00 30.49 ? 682 ASN A CG 1 ATOM 5623 O OD1 . ASN A 1 682 ? 42.485 63.658 -41.671 1.00 34.95 ? 682 ASN A OD1 1 ATOM 5624 N ND2 . ASN A 1 682 ? 43.626 63.283 -43.579 1.00 34.25 ? 682 ASN A ND2 1 ATOM 5625 N N . GLY A 1 683 ? 40.042 66.110 -40.662 1.00 24.18 ? 683 GLY A N 1 ATOM 5626 C CA . GLY A 1 683 ? 39.296 65.776 -39.465 1.00 21.91 ? 683 GLY A CA 1 ATOM 5627 C C . GLY A 1 683 ? 37.828 66.068 -39.652 1.00 19.91 ? 683 GLY A C 1 ATOM 5628 O O . GLY A 1 683 ? 37.393 66.261 -40.783 1.00 20.21 ? 683 GLY A O 1 ATOM 5629 N N . PRO A 1 684 ? 37.054 66.133 -38.566 1.00 17.40 ? 684 PRO A N 1 ATOM 5630 C CA . PRO A 1 684 ? 35.613 66.390 -38.709 1.00 15.85 ? 684 PRO A CA 1 ATOM 5631 C C . PRO A 1 684 ? 35.316 67.825 -39.164 1.00 14.37 ? 684 PRO A C 1 ATOM 5632 O O . PRO A 1 684 ? 36.151 68.703 -38.964 1.00 13.92 ? 684 PRO A O 1 ATOM 5633 C CB . PRO A 1 684 ? 35.057 66.147 -37.301 1.00 15.70 ? 684 PRO A CB 1 ATOM 5634 C CG . PRO A 1 684 ? 36.261 66.322 -36.365 1.00 17.09 ? 684 PRO A CG 1 ATOM 5635 C CD . PRO A 1 684 ? 37.457 65.979 -37.156 1.00 17.74 ? 684 PRO A CD 1 ATOM 5636 N N . THR A 1 685 ? 34.152 68.019 -39.758 1.00 13.02 ? 685 THR A N 1 ATOM 5637 C CA . THR A 1 685 ? 33.646 69.349 -40.062 1.00 12.46 ? 685 THR A CA 1 ATOM 5638 C C . THR A 1 685 ? 32.619 69.661 -38.995 1.00 12.18 ? 685 THR A C 1 ATOM 5639 O O . THR A 1 685 ? 31.675 68.897 -38.799 1.00 12.26 ? 685 THR A O 1 ATOM 5640 C CB . THR A 1 685 ? 32.991 69.344 -41.443 1.00 13.31 ? 685 THR A CB 1 ATOM 5641 O OG1 . THR A 1 685 ? 33.999 69.084 -42.422 1.00 15.66 ? 685 THR A OG1 1 ATOM 5642 C CG2 . THR A 1 685 ? 32.485 70.739 -41.778 1.00 15.45 ? 685 THR A CG2 1 ATOM 5643 N N . LEU A 1 686 ? 32.775 70.819 -38.355 1.00 10.50 ? 686 LEU A N 1 ATOM 5644 C CA . LEU A 1 686 ? 31.884 71.260 -37.305 1.00 11.09 ? 686 LEU A CA 1 ATOM 5645 C C . LEU A 1 686 ? 31.111 72.470 -37.796 1.00 10.55 ? 686 LEU A C 1 ATOM 5646 O O . LEU A 1 686 ? 31.702 73.391 -38.400 1.00 11.36 ? 686 LEU A O 1 ATOM 5647 C CB . LEU A 1 686 ? 32.689 71.679 -36.072 1.00 11.11 ? 686 LEU A CB 1 ATOM 5648 C CG . LEU A 1 686 ? 33.559 70.661 -35.339 1.00 16.50 ? 686 LEU A CG 1 ATOM 5649 C CD1 . LEU A 1 686 ? 33.675 71.094 -33.865 1.00 15.88 ? 686 LEU A CD1 1 ATOM 5650 C CD2 . LEU A 1 686 ? 33.157 69.230 -35.484 1.00 16.65 ? 686 LEU A CD2 1 ATOM 5651 N N . ALA A 1 687 ? 29.826 72.474 -37.492 1.00 10.41 ? 687 ALA A N 1 ATOM 5652 C CA . ALA A 1 687 ? 28.960 73.595 -37.841 1.00 10.45 ? 687 ALA A CA 1 ATOM 5653 C C . ALA A 1 687 ? 28.517 74.284 -36.573 1.00 10.98 ? 687 ALA A C 1 ATOM 5654 O O . ALA A 1 687 ? 28.250 73.619 -35.567 1.00 10.04 ? 687 ALA A O 1 ATOM 5655 C CB . ALA A 1 687 ? 27.756 73.127 -38.657 1.00 11.29 ? 687 ALA A CB 1 ATOM 5656 N N . PHE A 1 688 ? 28.464 75.616 -36.607 1.00 9.61 ? 688 PHE A N 1 ATOM 5657 C CA . PHE A 1 688 ? 28.129 76.410 -35.429 1.00 9.46 ? 688 PHE A CA 1 ATOM 5658 C C . PHE A 1 688 ? 26.945 77.300 -35.703 1.00 10.48 ? 688 PHE A C 1 ATOM 5659 O O . PHE A 1 688 ? 26.780 77.804 -36.823 1.00 11.36 ? 688 PHE A O 1 ATOM 5660 C CB . PHE A 1 688 ? 29.321 77.281 -35.010 1.00 9.68 ? 688 PHE A CB 1 ATOM 5661 C CG . PHE A 1 688 ? 30.536 76.491 -34.667 1.00 8.23 ? 688 PHE A CG 1 ATOM 5662 C CD1 . PHE A 1 688 ? 31.380 76.020 -35.640 1.00 8.89 ? 688 PHE A CD1 1 ATOM 5663 C CD2 . PHE A 1 688 ? 30.834 76.213 -33.343 1.00 9.60 ? 688 PHE A CD2 1 ATOM 5664 C CE1 . PHE A 1 688 ? 32.498 75.262 -35.322 1.00 9.18 ? 688 PHE A CE1 1 ATOM 5665 C CE2 . PHE A 1 688 ? 31.952 75.481 -33.038 1.00 8.74 ? 688 PHE A CE2 1 ATOM 5666 C CZ . PHE A 1 688 ? 32.770 74.993 -34.004 1.00 9.19 ? 688 PHE A CZ 1 ATOM 5667 N N . SER A 1 689 ? 26.145 77.539 -34.689 1.00 10.74 ? 689 SER A N 1 ATOM 5668 C CA . SER A 1 689 ? 25.035 78.495 -34.787 1.00 11.49 ? 689 SER A CA 1 ATOM 5669 C C . SER A 1 689 ? 25.563 79.933 -34.817 1.00 11.37 ? 689 SER A C 1 ATOM 5670 O O . SER A 1 689 ? 26.738 80.209 -34.552 1.00 10.53 ? 689 SER A O 1 ATOM 5671 C CB . SER A 1 689 ? 24.113 78.347 -33.598 1.00 11.78 ? 689 SER A CB 1 ATOM 5672 O OG . SER A 1 689 ? 24.713 78.907 -32.442 1.00 12.08 ? 689 SER A OG 1 ATOM 5673 N N . GLU A 1 690 ? 24.671 80.862 -35.126 1.00 12.55 ? 690 GLU A N 1 ATOM 5674 C CA . GLU A 1 690 ? 25.049 82.268 -35.076 1.00 13.07 ? 690 GLU A CA 1 ATOM 5675 C C . GLU A 1 690 ? 25.455 82.777 -33.692 1.00 13.12 ? 690 GLU A C 1 ATOM 5676 O O . GLU A 1 690 ? 26.058 83.845 -33.588 1.00 13.28 ? 690 GLU A O 1 ATOM 5677 C CB . GLU A 1 690 ? 23.954 83.143 -35.687 1.00 14.26 ? 690 GLU A CB 1 ATOM 5678 C CG . GLU A 1 690 ? 22.800 83.491 -34.785 1.00 19.14 ? 690 GLU A CG 1 ATOM 5679 C CD . GLU A 1 690 ? 21.943 84.556 -35.445 1.00 25.51 ? 690 GLU A CD 1 ATOM 5680 O OE1 . GLU A 1 690 ? 21.408 84.275 -36.545 1.00 28.67 ? 690 GLU A OE1 1 ATOM 5681 O OE2 . GLU A 1 690 ? 21.834 85.673 -34.888 1.00 30.29 ? 690 GLU A OE2 1 ATOM 5682 N N . GLN A 1 691 ? 25.117 82.006 -32.642 1.00 13.21 ? 691 GLN A N 1 ATOM 5683 C CA . GLN A 1 691 ? 25.594 82.311 -31.287 1.00 12.99 ? 691 GLN A CA 1 ATOM 5684 C C . GLN A 1 691 ? 26.925 81.653 -30.934 1.00 12.36 ? 691 GLN A C 1 ATOM 5685 O O . GLN A 1 691 ? 27.358 81.728 -29.788 1.00 13.77 ? 691 GLN A O 1 ATOM 5686 C CB . GLN A 1 691 ? 24.556 81.948 -30.236 1.00 14.56 ? 691 GLN A CB 1 ATOM 5687 C CG . GLN A 1 691 ? 23.337 82.789 -30.323 1.00 19.33 ? 691 GLN A CG 1 ATOM 5688 C CD . GLN A 1 691 ? 22.187 81.917 -30.460 1.00 26.26 ? 691 GLN A CD 1 ATOM 5689 O OE1 . GLN A 1 691 ? 21.519 81.614 -29.470 1.00 27.37 ? 691 GLN A OE1 1 ATOM 5690 N NE2 . GLN A 1 691 ? 21.973 81.413 -31.678 1.00 26.44 ? 691 GLN A NE2 1 ATOM 5691 N N . GLY A 1 692 ? 27.566 81.026 -31.909 1.00 11.17 ? 692 GLY A N 1 ATOM 5692 C CA . GLY A 1 692 ? 28.906 80.477 -31.721 1.00 11.76 ? 692 GLY A CA 1 ATOM 5693 C C . GLY A 1 692 ? 28.907 79.120 -31.050 1.00 11.00 ? 692 GLY A C 1 ATOM 5694 O O . GLY A 1 692 ? 29.941 78.703 -30.565 1.00 11.95 ? 692 GLY A O 1 ATOM 5695 N N . LEU A 1 693 ? 27.769 78.445 -30.995 1.00 10.94 ? 693 LEU A N 1 ATOM 5696 C CA . LEU A 1 693 ? 27.667 77.152 -30.300 1.00 10.86 ? 693 LEU A CA 1 ATOM 5697 C C . LEU A 1 693 ? 27.542 76.033 -31.310 1.00 10.15 ? 693 LEU A C 1 ATOM 5698 O O . LEU A 1 693 ? 26.817 76.154 -32.312 1.00 10.05 ? 693 LEU A O 1 ATOM 5699 C CB . LEU A 1 693 ? 26.445 77.152 -29.386 1.00 11.67 ? 693 LEU A CB 1 ATOM 5700 C CG . LEU A 1 693 ? 26.522 78.137 -28.213 1.00 14.59 ? 693 LEU A CG 1 ATOM 5701 C CD1 . LEU A 1 693 ? 25.117 78.525 -27.785 1.00 18.67 ? 693 LEU A CD1 1 ATOM 5702 C CD2 . LEU A 1 693 ? 27.263 77.496 -27.066 1.00 17.22 ? 693 LEU A CD2 1 ATOM 5703 N N . LEU A 1 694 ? 28.241 74.937 -31.060 1.00 9.09 ? 694 LEU A N 1 ATOM 5704 C CA . LEU A 1 694 ? 28.173 73.777 -31.932 1.00 9.31 ? 694 LEU A CA 1 ATOM 5705 C C . LEU A 1 694 ? 26.730 73.369 -32.207 1.00 9.17 ? 694 LEU A C 1 ATOM 5706 O O . LEU A 1 694 ? 25.885 73.361 -31.310 1.00 9.34 ? 694 LEU A O 1 ATOM 5707 C CB . LEU A 1 694 ? 28.896 72.590 -31.278 1.00 10.07 ? 694 LEU A CB 1 ATOM 5708 C CG . LEU A 1 694 ? 29.120 71.376 -32.171 1.00 11.08 ? 694 LEU A CG 1 ATOM 5709 C CD1 . LEU A 1 694 ? 30.074 71.698 -33.268 1.00 11.75 ? 694 LEU A CD1 1 ATOM 5710 C CD2 . LEU A 1 694 ? 29.633 70.224 -31.309 1.00 12.34 ? 694 LEU A CD2 1 ATOM 5711 N N . LYS A 1 695 ? 26.460 73.055 -33.477 1.00 9.84 ? 695 LYS A N 1 ATOM 5712 C CA . LYS A 1 695 ? 25.178 72.482 -33.850 1.00 11.72 ? 695 LYS A CA 1 ATOM 5713 C C . LYS A 1 695 ? 25.294 71.127 -34.539 1.00 11.23 ? 695 LYS A C 1 ATOM 5714 O O . LYS A 1 695 ? 24.334 70.368 -34.478 1.00 12.78 ? 695 LYS A O 1 ATOM 5715 C CB . LYS A 1 695 ? 24.348 73.459 -34.688 1.00 13.61 ? 695 LYS A CB 1 ATOM 5716 C CG . LYS A 1 695 ? 24.996 73.931 -35.933 1.00 16.94 ? 695 LYS A CG 1 ATOM 5717 C CD . LYS A 1 695 ? 24.075 74.940 -36.655 1.00 21.80 ? 695 LYS A CD 1 ATOM 5718 C CE . LYS A 1 695 ? 22.809 74.267 -37.133 1.00 26.95 ? 695 LYS A CE 1 ATOM 5719 N NZ . LYS A 1 695 ? 22.086 75.125 -38.129 1.00 29.58 ? 695 LYS A NZ 1 ATOM 5720 N N . SER A 1 696 ? 26.417 70.810 -35.159 1.00 10.54 ? 696 SER A N 1 ATOM 5721 C CA . SER A 1 696 ? 26.551 69.528 -35.862 1.00 11.03 ? 696 SER A CA 1 ATOM 5722 C C . SER A 1 696 ? 27.995 69.154 -36.092 1.00 11.09 ? 696 SER A C 1 ATOM 5723 O O . SER A 1 696 ? 28.883 70.024 -36.141 1.00 11.20 ? 696 SER A O 1 ATOM 5724 C CB . SER A 1 696 ? 25.755 69.512 -37.188 1.00 12.63 ? 696 SER A CB 1 ATOM 5725 O OG . SER A 1 696 ? 26.448 70.272 -38.159 1.00 15.53 ? 696 SER A OG 1 ATOM 5726 N N . ILE A 1 697 ? 28.234 67.840 -36.248 1.00 10.87 ? 697 ILE A N 1 ATOM 5727 C CA . ILE A 1 697 ? 29.538 67.281 -36.547 1.00 11.63 ? 697 ILE A CA 1 ATOM 5728 C C . ILE A 1 697 ? 29.414 66.333 -37.721 1.00 12.33 ? 697 ILE A C 1 ATOM 5729 O O . ILE A 1 697 ? 28.551 65.454 -37.694 1.00 13.43 ? 697 ILE A O 1 ATOM 5730 C CB . ILE A 1 697 ? 30.113 66.490 -35.337 1.00 11.18 ? 697 ILE A CB 1 ATOM 5731 C CG1 . ILE A 1 697 ? 30.214 67.411 -34.113 1.00 10.74 ? 697 ILE A CG1 1 ATOM 5732 C CG2 . ILE A 1 697 ? 31.472 65.872 -35.719 1.00 12.63 ? 697 ILE A CG2 1 ATOM 5733 C CD1 . ILE A 1 697 ? 30.647 66.687 -32.831 1.00 12.48 ? 697 ILE A CD1 1 ATOM 5734 N N . GLN A 1 698 ? 30.278 66.505 -38.709 1.00 12.29 ? 698 GLN A N 1 ATOM 5735 C CA . GLN A 1 698 ? 30.322 65.599 -39.844 1.00 13.66 ? 698 GLN A CA 1 ATOM 5736 C C . GLN A 1 698 ? 31.668 64.914 -39.814 1.00 14.16 ? 698 GLN A C 1 ATOM 5737 O O . GLN A 1 698 ? 32.696 65.559 -39.985 1.00 14.59 ? 698 GLN A O 1 ATOM 5738 C CB . GLN A 1 698 ? 30.144 66.395 -41.139 1.00 14.22 ? 698 GLN A CB 1 ATOM 5739 C CG . GLN A 1 698 ? 30.138 65.478 -42.361 1.00 18.10 ? 698 GLN A CG 1 ATOM 5740 C CD . GLN A 1 698 ? 30.295 66.245 -43.651 1.00 19.93 ? 698 GLN A CD 1 ATOM 5741 O OE1 . GLN A 1 698 ? 31.192 67.074 -43.780 1.00 22.57 ? 698 GLN A OE1 1 ATOM 5742 N NE2 . GLN A 1 698 ? 29.430 65.954 -44.618 1.00 24.07 ? 698 GLN A NE2 1 ATOM 5743 N N . LEU A 1 699 ? 31.685 63.601 -39.565 1.00 16.41 ? 699 LEU A N 1 ATOM 5744 C CA . LEU A 1 699 ? 32.957 62.916 -39.357 1.00 18.95 ? 699 LEU A CA 1 ATOM 5745 C C . LEU A 1 699 ? 33.869 62.832 -40.591 1.00 21.30 ? 699 LEU A C 1 ATOM 5746 O O . LEU A 1 699 ? 35.089 62.984 -40.466 1.00 22.74 ? 699 LEU A O 1 ATOM 5747 C CB . LEU A 1 699 ? 32.729 61.528 -38.729 1.00 18.96 ? 699 LEU A CB 1 ATOM 5748 C CG . LEU A 1 699 ? 32.056 61.510 -37.349 1.00 18.58 ? 699 LEU A CG 1 ATOM 5749 C CD1 . LEU A 1 699 ? 31.825 60.054 -36.891 1.00 21.47 ? 699 LEU A CD1 1 ATOM 5750 C CD2 . LEU A 1 699 ? 32.868 62.310 -36.321 1.00 17.56 ? 699 LEU A CD2 1 ATOM 5751 N N . THR A 1 700 ? 33.278 62.615 -41.766 1.00 24.07 ? 700 THR A N 1 ATOM 5752 C CA . THR A 1 700 ? 34.039 62.491 -43.017 1.00 27.30 ? 700 THR A CA 1 ATOM 5753 C C . THR A 1 700 ? 33.311 63.225 -44.146 1.00 28.78 ? 700 THR A C 1 ATOM 5754 O O . THR A 1 700 ? 32.138 63.543 -44.012 1.00 28.63 ? 700 THR A O 1 ATOM 5755 C CB . THR A 1 700 ? 34.246 60.991 -43.403 1.00 27.35 ? 700 THR A CB 1 ATOM 5756 O OG1 . THR A 1 700 ? 32.973 60.342 -43.522 1.00 28.92 ? 700 THR A OG1 1 ATOM 5757 C CG2 . THR A 1 700 ? 34.963 60.199 -42.289 1.00 28.48 ? 700 THR A CG2 1 ATOM 5758 N N . GLN A 1 701 ? 34.007 63.469 -45.260 1.00 31.20 ? 701 GLN A N 1 ATOM 5759 C CA . GLN A 1 701 ? 33.474 64.258 -46.387 1.00 33.59 ? 701 GLN A CA 1 ATOM 5760 C C . GLN A 1 701 ? 32.087 63.808 -46.867 1.00 34.32 ? 701 GLN A C 1 ATOM 5761 O O . GLN A 1 701 ? 31.213 64.642 -47.137 1.00 35.32 ? 701 GLN A O 1 ATOM 5762 C CB . GLN A 1 701 ? 34.452 64.239 -47.580 1.00 34.26 ? 701 GLN A CB 1 ATOM 5763 C CG . GLN A 1 701 ? 35.668 65.148 -47.446 1.00 36.52 ? 701 GLN A CG 1 ATOM 5764 C CD . GLN A 1 701 ? 35.391 66.605 -47.830 1.00 40.04 ? 701 GLN A CD 1 ATOM 5765 O OE1 . GLN A 1 701 ? 35.849 67.530 -47.150 1.00 40.42 ? 701 GLN A OE1 1 ATOM 5766 N NE2 . GLN A 1 701 ? 34.643 66.810 -48.915 1.00 41.02 ? 701 GLN A NE2 1 ATOM 5767 N N . ASP A 1 702 ? 31.897 62.496 -46.968 1.00 34.85 ? 702 ASP A N 1 ATOM 5768 C CA . ASP A 1 702 ? 30.670 61.921 -47.513 1.00 35.61 ? 702 ASP A CA 1 ATOM 5769 C C . ASP A 1 702 ? 29.637 61.543 -46.442 1.00 35.07 ? 702 ASP A C 1 ATOM 5770 O O . ASP A 1 702 ? 28.548 61.068 -46.770 1.00 35.70 ? 702 ASP A O 1 ATOM 5771 C CB . ASP A 1 702 ? 31.018 60.673 -48.323 1.00 36.38 ? 702 ASP A CB 1 ATOM 5772 C CG . ASP A 1 702 ? 31.605 59.578 -47.454 1.00 38.33 ? 702 ASP A CG 1 ATOM 5773 O OD1 . ASP A 1 702 ? 32.834 59.608 -47.205 1.00 40.92 ? 702 ASP A OD1 1 ATOM 5774 O OD2 . ASP A 1 702 ? 30.907 58.663 -46.952 1.00 41.04 ? 702 ASP A OD2 1 ATOM 5775 N N . SER A 1 703 ? 29.978 61.745 -45.167 1.00 33.82 ? 703 SER A N 1 ATOM 5776 C CA . SER A 1 703 ? 29.101 61.337 -44.068 1.00 31.94 ? 703 SER A CA 1 ATOM 5777 C C . SER A 1 703 ? 28.066 62.417 -43.717 1.00 30.15 ? 703 SER A C 1 ATOM 5778 O O . SER A 1 703 ? 28.203 63.561 -44.148 1.00 30.43 ? 703 SER A O 1 ATOM 5779 C CB . SER A 1 703 ? 29.929 60.943 -42.840 1.00 31.99 ? 703 SER A CB 1 ATOM 5780 O OG . SER A 1 703 ? 30.633 62.054 -42.312 1.00 32.45 ? 703 SER A OG 1 ATOM 5781 N N . PRO A 1 704 ? 27.034 62.062 -42.947 1.00 28.84 ? 704 PRO A N 1 ATOM 5782 C CA . PRO A 1 704 ? 25.993 63.021 -42.559 1.00 27.29 ? 704 PRO A CA 1 ATOM 5783 C C . PRO A 1 704 ? 26.452 64.048 -41.512 1.00 25.59 ? 704 PRO A C 1 ATOM 5784 O O . PRO A 1 704 ? 27.388 63.794 -40.745 1.00 25.23 ? 704 PRO A O 1 ATOM 5785 C CB . PRO A 1 704 ? 24.897 62.131 -41.955 1.00 28.08 ? 704 PRO A CB 1 ATOM 5786 C CG . PRO A 1 704 ? 25.284 60.738 -42.278 1.00 28.21 ? 704 PRO A CG 1 ATOM 5787 C CD . PRO A 1 704 ? 26.774 60.724 -42.386 1.00 29.07 ? 704 PRO A CD 1 ATOM 5788 N N . HIS A 1 705 ? 25.791 65.204 -41.505 1.00 23.91 ? 705 HIS A N 1 ATOM 5789 C CA . HIS A 1 705 ? 25.963 66.194 -40.441 1.00 22.78 ? 705 HIS A CA 1 ATOM 5790 C C . HIS A 1 705 ? 25.098 65.787 -39.256 1.00 21.19 ? 705 HIS A C 1 ATOM 5791 O O . HIS A 1 705 ? 23.900 66.007 -39.237 1.00 22.18 ? 705 HIS A O 1 ATOM 5792 C CB . HIS A 1 705 ? 25.609 67.596 -40.961 1.00 23.38 ? 705 HIS A CB 1 ATOM 5793 C CG . HIS A 1 705 ? 26.492 68.039 -42.084 1.00 25.57 ? 705 HIS A CG 1 ATOM 5794 N ND1 . HIS A 1 705 ? 27.624 68.802 -41.890 1.00 26.34 ? 705 HIS A ND1 1 ATOM 5795 C CD2 . HIS A 1 705 ? 26.435 67.781 -43.414 1.00 27.42 ? 705 HIS A CD2 1 ATOM 5796 C CE1 . HIS A 1 705 ? 28.224 69.001 -43.051 1.00 27.42 ? 705 HIS A CE1 1 ATOM 5797 N NE2 . HIS A 1 705 ? 27.522 68.393 -43.992 1.00 27.84 ? 705 HIS A NE2 1 ATOM 5798 N N . VAL A 1 706 ? 25.738 65.186 -38.249 1.00 18.18 ? 706 VAL A N 1 ATOM 5799 C CA . VAL A 1 706 ? 25.044 64.677 -37.074 1.00 15.84 ? 706 VAL A CA 1 ATOM 5800 C C . VAL A 1 706 ? 24.746 65.808 -36.094 1.00 14.86 ? 706 VAL A C 1 ATOM 5801 O O . VAL A 1 706 ? 25.679 66.485 -35.668 1.00 13.23 ? 706 VAL A O 1 ATOM 5802 C CB . VAL A 1 706 ? 25.955 63.648 -36.350 1.00 15.53 ? 706 VAL A CB 1 ATOM 5803 C CG1 . VAL A 1 706 ? 25.257 63.082 -35.129 1.00 14.89 ? 706 VAL A CG1 1 ATOM 5804 C CG2 . VAL A 1 706 ? 26.422 62.532 -37.314 1.00 15.72 ? 706 VAL A CG2 1 ATOM 5805 N N . PRO A 1 707 ? 23.483 66.044 -35.737 1.00 14.20 ? 707 PRO A N 1 ATOM 5806 C CA . PRO A 1 707 ? 23.132 67.083 -34.763 1.00 14.07 ? 707 PRO A CA 1 ATOM 5807 C C . PRO A 1 707 ? 23.780 66.832 -33.401 1.00 13.50 ? 707 PRO A C 1 ATOM 5808 O O . PRO A 1 707 ? 23.628 65.782 -32.790 1.00 13.44 ? 707 PRO A O 1 ATOM 5809 C CB . PRO A 1 707 ? 21.603 66.986 -34.652 1.00 14.59 ? 707 PRO A CB 1 ATOM 5810 C CG . PRO A 1 707 ? 21.166 66.281 -35.877 1.00 16.22 ? 707 PRO A CG 1 ATOM 5811 C CD . PRO A 1 707 ? 22.277 65.372 -36.279 1.00 14.36 ? 707 PRO A CD 1 ATOM 5812 N N . VAL A 1 708 ? 24.548 67.810 -32.957 1.00 12.56 ? 708 VAL A N 1 ATOM 5813 C CA . VAL A 1 708 ? 25.152 67.818 -31.638 1.00 11.49 ? 708 VAL A CA 1 ATOM 5814 C C . VAL A 1 708 ? 25.133 69.285 -31.220 1.00 11.21 ? 708 VAL A C 1 ATOM 5815 O O . VAL A 1 708 ? 25.849 70.090 -31.775 1.00 11.81 ? 708 VAL A O 1 ATOM 5816 C CB . VAL A 1 708 ? 26.617 67.303 -31.678 1.00 11.28 ? 708 VAL A CB 1 ATOM 5817 C CG1 . VAL A 1 708 ? 27.224 67.294 -30.279 1.00 11.77 ? 708 VAL A CG1 1 ATOM 5818 C CG2 . VAL A 1 708 ? 26.698 65.892 -32.307 1.00 12.41 ? 708 VAL A CG2 1 ATOM 5819 N N A HIS A 1 709 ? 24.233 69.634 -30.314 0.50 10.17 ? 709 HIS A N 1 ATOM 5820 N N B HIS A 1 709 ? 24.195 69.646 -30.368 0.50 10.62 ? 709 HIS A N 1 ATOM 5821 C CA A HIS A 1 709 ? 23.920 71.034 -29.985 0.50 10.38 ? 709 HIS A CA 1 ATOM 5822 C CA B HIS A 1 709 ? 24.054 71.048 -30.004 0.50 11.19 ? 709 HIS A CA 1 ATOM 5823 C C A HIS A 1 709 ? 24.326 71.409 -28.556 0.50 10.31 ? 709 HIS A C 1 ATOM 5824 C C B HIS A 1 709 ? 24.507 71.270 -28.581 0.50 10.78 ? 709 HIS A C 1 ATOM 5825 O O A HIS A 1 709 ? 23.735 70.882 -27.605 0.50 10.46 ? 709 HIS A O 1 ATOM 5826 O O B HIS A 1 709 ? 24.165 70.507 -27.683 0.50 10.58 ? 709 HIS A O 1 ATOM 5827 C CB A HIS A 1 709 ? 22.421 71.258 -30.137 0.50 10.41 ? 709 HIS A CB 1 ATOM 5828 C CB B HIS A 1 709 ? 22.629 71.548 -30.198 0.50 11.64 ? 709 HIS A CB 1 ATOM 5829 C CG A HIS A 1 709 ? 21.972 71.409 -31.555 0.50 11.53 ? 709 HIS A CG 1 ATOM 5830 C CG B HIS A 1 709 ? 22.469 73.025 -29.965 0.50 14.42 ? 709 HIS A CG 1 ATOM 5831 N ND1 A HIS A 1 709 ? 21.825 70.336 -32.406 0.50 15.74 ? 709 HIS A ND1 1 ATOM 5832 N ND1 B HIS A 1 709 ? 23.336 73.964 -30.489 0.50 17.18 ? 709 HIS A ND1 1 ATOM 5833 C CD2 A HIS A 1 709 ? 21.665 72.509 -32.279 0.50 14.16 ? 709 HIS A CD2 1 ATOM 5834 C CD2 B HIS A 1 709 ? 21.536 73.723 -29.275 0.50 18.42 ? 709 HIS A CD2 1 ATOM 5835 C CE1 A HIS A 1 709 ? 21.438 70.769 -33.592 0.50 13.11 ? 709 HIS A CE1 1 ATOM 5836 C CE1 B HIS A 1 709 ? 22.955 75.171 -30.117 0.50 18.45 ? 709 HIS A CE1 1 ATOM 5837 N NE2 A HIS A 1 709 ? 21.320 72.082 -33.538 0.50 17.06 ? 709 HIS A NE2 1 ATOM 5838 N NE2 B HIS A 1 709 ? 21.862 75.054 -29.385 0.50 18.63 ? 709 HIS A NE2 1 ATOM 5839 N N . PHE A 1 710 ? 25.316 72.307 -28.405 1.00 9.63 ? 710 PHE A N 1 ATOM 5840 C CA . PHE A 1 710 ? 25.686 72.798 -27.077 1.00 10.13 ? 710 PHE A CA 1 ATOM 5841 C C . PHE A 1 710 ? 24.684 73.864 -26.643 1.00 11.04 ? 710 PHE A C 1 ATOM 5842 O O . PHE A 1 710 ? 24.275 74.740 -27.448 1.00 10.78 ? 710 PHE A O 1 ATOM 5843 C CB . PHE A 1 710 ? 27.092 73.418 -27.035 1.00 10.45 ? 710 PHE A CB 1 ATOM 5844 C CG . PHE A 1 710 ? 28.198 72.467 -26.658 1.00 12.13 ? 710 PHE A CG 1 ATOM 5845 C CD1 . PHE A 1 710 ? 28.191 71.824 -25.428 1.00 15.52 ? 710 PHE A CD1 1 ATOM 5846 C CD2 . PHE A 1 710 ? 29.300 72.296 -27.479 1.00 17.07 ? 710 PHE A CD2 1 ATOM 5847 C CE1 . PHE A 1 710 ? 29.209 70.956 -25.049 1.00 18.03 ? 710 PHE A CE1 1 ATOM 5848 C CE2 . PHE A 1 710 ? 30.333 71.413 -27.087 1.00 15.25 ? 710 PHE A CE2 1 ATOM 5849 C CZ . PHE A 1 710 ? 30.284 70.778 -25.870 1.00 14.90 ? 710 PHE A CZ 1 ATOM 5850 N N . LYS A 1 711 ? 24.294 73.826 -25.383 1.00 9.77 ? 711 LYS A N 1 ATOM 5851 C CA . LYS A 1 711 ? 23.368 74.797 -24.794 1.00 11.96 ? 711 LYS A CA 1 ATOM 5852 C C . LYS A 1 711 ? 23.797 75.039 -23.371 1.00 10.70 ? 711 LYS A C 1 ATOM 5853 O O . LYS A 1 711 ? 24.232 74.099 -22.703 1.00 11.52 ? 711 LYS A O 1 ATOM 5854 C CB . LYS A 1 711 ? 21.937 74.227 -24.821 1.00 12.82 ? 711 LYS A CB 1 ATOM 5855 C CG . LYS A 1 711 ? 20.824 75.188 -24.406 1.00 15.73 ? 711 LYS A CG 1 ATOM 5856 C CD . LYS A 1 711 ? 19.441 74.538 -24.550 1.00 17.42 ? 711 LYS A CD 1 ATOM 5857 C CE . LYS A 1 711 ? 18.911 74.668 -25.984 1.00 21.12 ? 711 LYS A CE 1 ATOM 5858 N NZ . LYS A 1 711 ? 17.734 73.774 -26.193 1.00 24.70 ? 711 LYS A NZ 1 ATOM 5859 N N . PHE A 1 712 ? 23.680 76.265 -22.887 1.00 8.54 ? 712 PHE A N 1 ATOM 5860 C CA . PHE A 1 712 ? 23.876 76.589 -21.484 1.00 8.72 ? 712 PHE A CA 1 ATOM 5861 C C . PHE A 1 712 ? 22.566 76.895 -20.794 1.00 8.62 ? 712 PHE A C 1 ATOM 5862 O O . PHE A 1 712 ? 21.733 77.612 -21.344 1.00 8.95 ? 712 PHE A O 1 ATOM 5863 C CB . PHE A 1 712 ? 24.872 77.756 -21.334 1.00 9.48 ? 712 PHE A CB 1 ATOM 5864 C CG . PHE A 1 712 ? 26.281 77.356 -21.638 1.00 8.68 ? 712 PHE A CG 1 ATOM 5865 C CD1 . PHE A 1 712 ? 26.751 77.381 -22.950 1.00 9.59 ? 712 PHE A CD1 1 ATOM 5866 C CD2 . PHE A 1 712 ? 27.130 76.878 -20.635 1.00 9.20 ? 712 PHE A CD2 1 ATOM 5867 C CE1 . PHE A 1 712 ? 28.048 76.972 -23.255 1.00 9.73 ? 712 PHE A CE1 1 ATOM 5868 C CE2 . PHE A 1 712 ? 28.400 76.458 -20.937 1.00 9.53 ? 712 PHE A CE2 1 ATOM 5869 C CZ . PHE A 1 712 ? 28.873 76.508 -22.240 1.00 8.71 ? 712 PHE A CZ 1 ATOM 5870 N N . LEU A 1 713 ? 22.354 76.308 -19.627 1.00 8.24 ? 713 LEU A N 1 ATOM 5871 C CA . LEU A 1 713 ? 21.135 76.516 -18.846 1.00 8.42 ? 713 LEU A CA 1 ATOM 5872 C C . LEU A 1 713 ? 21.463 76.814 -17.404 1.00 8.93 ? 713 LEU A C 1 ATOM 5873 O O . LEU A 1 713 ? 22.635 76.717 -16.993 1.00 9.34 ? 713 LEU A O 1 ATOM 5874 C CB . LEU A 1 713 ? 20.194 75.292 -18.940 1.00 8.76 ? 713 LEU A CB 1 ATOM 5875 C CG . LEU A 1 713 ? 19.880 74.849 -20.373 1.00 9.62 ? 713 LEU A CG 1 ATOM 5876 C CD1 . LEU A 1 713 ? 20.727 73.657 -20.784 1.00 11.99 ? 713 LEU A CD1 1 ATOM 5877 C CD2 . LEU A 1 713 ? 18.404 74.415 -20.474 1.00 11.98 ? 713 LEU A CD2 1 ATOM 5878 N N . LYS A 1 714 ? 20.467 77.171 -16.621 1.00 9.84 ? 714 LYS A N 1 ATOM 5879 C CA . LYS A 1 714 ? 20.690 77.451 -15.219 1.00 12.00 ? 714 LYS A CA 1 ATOM 5880 C C . LYS A 1 714 ? 19.631 76.769 -14.398 1.00 10.70 ? 714 LYS A C 1 ATOM 5881 O O . LYS A 1 714 ? 18.446 76.730 -14.780 1.00 11.28 ? 714 LYS A O 1 ATOM 5882 C CB . LYS A 1 714 ? 20.708 78.950 -14.884 1.00 14.85 ? 714 LYS A CB 1 ATOM 5883 C CG . LYS A 1 714 ? 19.634 79.760 -15.488 1.00 19.26 ? 714 LYS A CG 1 ATOM 5884 C CD . LYS A 1 714 ? 19.779 81.242 -15.073 1.00 18.76 ? 714 LYS A CD 1 ATOM 5885 C CE . LYS A 1 714 ? 21.123 81.842 -15.506 1.00 25.51 ? 714 LYS A CE 1 ATOM 5886 N NZ . LYS A 1 714 ? 21.233 83.316 -15.225 1.00 26.48 ? 714 LYS A NZ 1 ATOM 5887 N N . TYR A 1 715 ? 20.074 76.208 -13.277 1.00 8.09 ? 715 TYR A N 1 ATOM 5888 C CA . TYR A 1 715 ? 19.197 75.756 -12.234 1.00 8.16 ? 715 TYR A CA 1 ATOM 5889 C C . TYR A 1 715 ? 19.145 76.798 -11.125 1.00 9.54 ? 715 TYR A C 1 ATOM 5890 O O . TYR A 1 715 ? 20.132 77.501 -10.900 1.00 10.28 ? 715 TYR A O 1 ATOM 5891 C CB . TYR A 1 715 ? 19.751 74.462 -11.620 1.00 8.51 ? 715 TYR A CB 1 ATOM 5892 C CG . TYR A 1 715 ? 19.681 73.240 -12.489 1.00 8.31 ? 715 TYR A CG 1 ATOM 5893 C CD1 . TYR A 1 715 ? 18.501 72.515 -12.575 1.00 6.22 ? 715 TYR A CD1 1 ATOM 5894 C CD2 . TYR A 1 715 ? 20.811 72.767 -13.191 1.00 8.58 ? 715 TYR A CD2 1 ATOM 5895 C CE1 . TYR A 1 715 ? 18.430 71.356 -13.337 1.00 8.09 ? 715 TYR A CE1 1 ATOM 5896 C CE2 . TYR A 1 715 ? 20.736 71.622 -13.966 1.00 7.66 ? 715 TYR A CE2 1 ATOM 5897 C CZ . TYR A 1 715 ? 19.544 70.907 -14.042 1.00 7.56 ? 715 TYR A CZ 1 ATOM 5898 O OH . TYR A 1 715 ? 19.481 69.732 -14.790 1.00 7.57 ? 715 TYR A OH 1 ATOM 5899 N N . GLY A 1 716 ? 18.041 76.835 -10.401 1.00 9.60 ? 716 GLY A N 1 ATOM 5900 C CA . GLY A 1 716 ? 17.892 77.738 -9.293 1.00 9.99 ? 716 GLY A CA 1 ATOM 5901 C C . GLY A 1 716 ? 17.723 76.962 -8.005 1.00 10.33 ? 716 GLY A C 1 ATOM 5902 O O . GLY A 1 716 ? 18.054 75.786 -7.922 1.00 11.19 ? 716 GLY A O 1 ATOM 5903 N N . VAL A 1 717 ? 17.232 77.648 -6.991 1.00 10.94 ? 717 VAL A N 1 ATOM 5904 C CA . VAL A 1 717 ? 17.103 77.104 -5.648 1.00 12.51 ? 717 VAL A CA 1 ATOM 5905 C C . VAL A 1 717 ? 15.632 77.204 -5.250 1.00 13.54 ? 717 VAL A C 1 ATOM 5906 O O . VAL A 1 717 ? 14.922 78.080 -5.742 1.00 15.12 ? 717 VAL A O 1 ATOM 5907 C CB . VAL A 1 717 ? 18.060 77.902 -4.704 1.00 12.91 ? 717 VAL A CB 1 ATOM 5908 C CG1 . VAL A 1 717 ? 17.844 77.622 -3.232 1.00 16.84 ? 717 VAL A CG1 1 ATOM 5909 C CG2 . VAL A 1 717 ? 19.502 77.602 -5.072 1.00 12.30 ? 717 VAL A CG2 1 ATOM 5910 N N . ARG A 1 718 ? 15.179 76.333 -4.361 1.00 12.90 ? 718 ARG A N 1 ATOM 5911 C CA . ARG A 1 718 ? 13.787 76.335 -3.900 1.00 14.88 ? 718 ARG A CA 1 ATOM 5912 C C . ARG A 1 718 ? 13.504 77.486 -2.961 1.00 16.90 ? 718 ARG A C 1 ATOM 5913 O O . ARG A 1 718 ? 14.292 77.803 -2.081 1.00 17.85 ? 718 ARG A O 1 ATOM 5914 C CB . ARG A 1 718 ? 13.461 75.005 -3.212 1.00 14.37 ? 718 ARG A CB 1 ATOM 5915 C CG . ARG A 1 718 ? 13.527 73.862 -4.169 1.00 14.23 ? 718 ARG A CG 1 ATOM 5916 C CD . ARG A 1 718 ? 13.540 72.508 -3.510 1.00 13.75 ? 718 ARG A CD 1 ATOM 5917 N NE . ARG A 1 718 ? 13.812 71.495 -4.515 1.00 13.96 ? 718 ARG A NE 1 ATOM 5918 C CZ . ARG A 1 718 ? 13.788 70.190 -4.281 1.00 13.16 ? 718 ARG A CZ 1 ATOM 5919 N NH1 . ARG A 1 718 ? 13.474 69.733 -3.067 1.00 13.35 ? 718 ARG A NH1 1 ATOM 5920 N NH2 . ARG A 1 718 ? 14.085 69.359 -5.265 1.00 14.28 ? 718 ARG A NH2 1 ATOM 5921 N N . SER A 1 719 ? 12.342 78.106 -3.144 1.00 19.49 ? 719 SER A N 1 ATOM 5922 C CA . SER A 1 719 ? 11.962 79.209 -2.274 1.00 21.84 ? 719 SER A CA 1 ATOM 5923 C C . SER A 1 719 ? 11.264 78.668 -1.029 1.00 23.36 ? 719 SER A C 1 ATOM 5924 O O . SER A 1 719 ? 11.174 79.355 -0.019 1.00 24.58 ? 719 SER A O 1 ATOM 5925 C CB . SER A 1 719 ? 11.086 80.206 -3.037 1.00 21.94 ? 719 SER A CB 1 ATOM 5926 O OG . SER A 1 719 ? 9.865 79.613 -3.409 1.00 25.00 ? 719 SER A OG 1 ATOM 5927 N N . HIS A 1 720 ? 10.765 77.434 -1.113 1.00 24.54 ? 720 HIS A N 1 ATOM 5928 C CA . HIS A 1 720 ? 10.182 76.741 0.031 1.00 25.69 ? 720 HIS A CA 1 ATOM 5929 C C . HIS A 1 720 ? 10.917 75.424 0.239 1.00 24.71 ? 720 HIS A C 1 ATOM 5930 O O . HIS A 1 720 ? 11.361 74.793 -0.725 1.00 25.31 ? 720 HIS A O 1 ATOM 5931 C CB . HIS A 1 720 ? 8.697 76.451 -0.210 1.00 27.19 ? 720 HIS A CB 1 ATOM 5932 C CG . HIS A 1 720 ? 7.941 77.613 -0.770 1.00 31.20 ? 720 HIS A CG 1 ATOM 5933 N ND1 . HIS A 1 720 ? 7.577 78.702 -0.007 1.00 35.48 ? 720 HIS A ND1 1 ATOM 5934 C CD2 . HIS A 1 720 ? 7.492 77.861 -2.024 1.00 34.92 ? 720 HIS A CD2 1 ATOM 5935 C CE1 . HIS A 1 720 ? 6.926 79.566 -0.765 1.00 36.19 ? 720 HIS A CE1 1 ATOM 5936 N NE2 . HIS A 1 720 ? 6.865 79.083 -1.993 1.00 37.04 ? 720 HIS A NE2 1 ATOM 5937 N N . GLY A 1 721 ? 11.028 74.997 1.489 1.00 23.41 ? 721 GLY A N 1 ATOM 5938 C CA . GLY A 1 721 ? 11.682 73.729 1.765 1.00 21.54 ? 721 GLY A CA 1 ATOM 5939 C C . GLY A 1 721 ? 13.188 73.837 1.607 1.00 20.14 ? 721 GLY A C 1 ATOM 5940 O O . GLY A 1 721 ? 13.763 74.929 1.616 1.00 20.67 ? 721 GLY A O 1 ATOM 5941 N N . ASP A 1 722 ? 13.822 72.689 1.430 1.00 17.33 ? 722 ASP A N 1 ATOM 5942 C CA . ASP A 1 722 ? 15.259 72.604 1.621 1.00 14.43 ? 722 ASP A CA 1 ATOM 5943 C C . ASP A 1 722 ? 16.033 73.329 0.532 1.00 12.44 ? 722 ASP A C 1 ATOM 5944 O O . ASP A 1 722 ? 15.706 73.268 -0.635 1.00 12.27 ? 722 ASP A O 1 ATOM 5945 C CB . ASP A 1 722 ? 15.703 71.150 1.748 1.00 14.10 ? 722 ASP A CB 1 ATOM 5946 C CG . ASP A 1 722 ? 15.070 70.427 2.940 1.00 14.61 ? 722 ASP A CG 1 ATOM 5947 O OD1 . ASP A 1 722 ? 14.848 71.073 4.014 1.00 17.27 ? 722 ASP A OD1 1 ATOM 5948 O OD2 . ASP A 1 722 ? 14.807 69.207 2.875 1.00 16.37 ? 722 ASP A OD2 1 ATOM 5949 N N . ARG A 1 723 ? 17.108 73.979 0.949 1.00 12.25 ? 723 ARG A N 1 ATOM 5950 C CA . ARG A 1 723 ? 17.931 74.745 0.028 1.00 12.46 ? 723 ARG A CA 1 ATOM 5951 C C . ARG A 1 723 ? 19.221 74.015 -0.355 1.00 11.28 ? 723 ARG A C 1 ATOM 5952 O O . ARG A 1 723 ? 19.827 73.337 0.491 1.00 11.16 ? 723 ARG A O 1 ATOM 5953 C CB . ARG A 1 723 ? 18.281 76.069 0.678 1.00 14.00 ? 723 ARG A CB 1 ATOM 5954 C CG . ARG A 1 723 ? 17.012 76.849 1.001 1.00 18.12 ? 723 ARG A CG 1 ATOM 5955 C CD . ARG A 1 723 ? 17.183 78.321 1.160 1.00 26.65 ? 723 ARG A CD 1 ATOM 5956 N NE . ARG A 1 723 ? 15.888 79.001 1.121 1.00 31.73 ? 723 ARG A NE 1 ATOM 5957 C CZ . ARG A 1 723 ? 15.599 80.085 1.828 1.00 34.81 ? 723 ARG A CZ 1 ATOM 5958 N NH1 . ARG A 1 723 ? 16.501 80.605 2.654 1.00 36.56 ? 723 ARG A NH1 1 ATOM 5959 N NH2 . ARG A 1 723 ? 14.400 80.640 1.724 1.00 34.82 ? 723 ARG A NH2 1 ATOM 5960 N N . SER A 1 724 ? 19.582 74.137 -1.636 1.00 10.21 ? 724 SER A N 1 ATOM 5961 C CA . SER A 1 724 ? 20.879 73.709 -2.122 1.00 10.18 ? 724 SER A CA 1 ATOM 5962 C C . SER A 1 724 ? 21.988 74.410 -1.352 1.00 9.48 ? 724 SER A C 1 ATOM 5963 O O . SER A 1 724 ? 21.858 75.582 -0.967 1.00 11.03 ? 724 SER A O 1 ATOM 5964 C CB . SER A 1 724 ? 21.031 74.047 -3.594 1.00 10.16 ? 724 SER A CB 1 ATOM 5965 O OG . SER A 1 724 ? 19.993 73.393 -4.330 1.00 9.80 ? 724 SER A OG 1 ATOM 5966 N N . GLY A 1 725 ? 23.099 73.708 -1.167 1.00 8.42 ? 725 GLY A N 1 ATOM 5967 C CA . GLY A 1 725 ? 24.283 74.280 -0.552 1.00 8.31 ? 725 GLY A CA 1 ATOM 5968 C C . GLY A 1 725 ? 25.483 73.531 -1.088 1.00 7.59 ? 725 GLY A C 1 ATOM 5969 O O . GLY A 1 725 ? 25.403 72.868 -2.131 1.00 8.22 ? 725 GLY A O 1 ATOM 5970 N N . ALA A 1 726 ? 26.607 73.614 -0.382 1.00 6.60 ? 726 ALA A N 1 ATOM 5971 C CA . ALA A 1 726 ? 27.823 72.980 -0.860 1.00 7.10 ? 726 ALA A CA 1 ATOM 5972 C C . ALA A 1 726 ? 27.680 71.486 -1.073 1.00 6.12 ? 726 ALA A C 1 ATOM 5973 O O . ALA A 1 726 ? 28.343 70.908 -1.940 1.00 5.82 ? 726 ALA A O 1 ATOM 5974 C CB . ALA A 1 726 ? 28.970 73.252 0.071 1.00 7.48 ? 726 ALA A CB 1 ATOM 5975 N N . TYR A 1 727 ? 26.842 70.829 -0.277 1.00 6.22 ? 727 TYR A N 1 ATOM 5976 C CA . TYR A 1 727 ? 26.643 69.370 -0.417 1.00 5.92 ? 727 TYR A CA 1 ATOM 5977 C C . TYR A 1 727 ? 25.490 68.977 -1.298 1.00 6.42 ? 727 TYR A C 1 ATOM 5978 O O . TYR A 1 727 ? 25.615 68.073 -2.136 1.00 6.37 ? 727 TYR A O 1 ATOM 5979 C CB . TYR A 1 727 ? 26.379 68.719 0.943 1.00 6.16 ? 727 TYR A CB 1 ATOM 5980 C CG . TYR A 1 727 ? 27.427 68.958 2.005 1.00 5.81 ? 727 TYR A CG 1 ATOM 5981 C CD1 . TYR A 1 727 ? 27.400 70.117 2.769 1.00 7.73 ? 727 TYR A CD1 1 ATOM 5982 C CD2 . TYR A 1 727 ? 28.403 67.996 2.288 1.00 8.82 ? 727 TYR A CD2 1 ATOM 5983 C CE1 . TYR A 1 727 ? 28.345 70.349 3.763 1.00 7.98 ? 727 TYR A CE1 1 ATOM 5984 C CE2 . TYR A 1 727 ? 29.350 68.219 3.293 1.00 8.29 ? 727 TYR A CE2 1 ATOM 5985 C CZ . TYR A 1 727 ? 29.305 69.373 4.015 1.00 7.39 ? 727 TYR A CZ 1 ATOM 5986 O OH . TYR A 1 727 ? 30.208 69.591 5.041 1.00 9.29 ? 727 TYR A OH 1 ATOM 5987 N N . LEU A 1 728 ? 24.333 69.591 -1.029 1.00 6.51 ? 728 LEU A N 1 ATOM 5988 C CA . LEU A 1 728 ? 23.064 69.144 -1.635 1.00 6.71 ? 728 LEU A CA 1 ATOM 5989 C C . LEU A 1 728 ? 22.711 69.918 -2.883 1.00 6.48 ? 728 LEU A C 1 ATOM 5990 O O . LEU A 1 728 ? 22.910 71.132 -2.961 1.00 7.96 ? 728 LEU A O 1 ATOM 5991 C CB . LEU A 1 728 ? 21.928 69.408 -0.650 1.00 8.15 ? 728 LEU A CB 1 ATOM 5992 C CG . LEU A 1 728 ? 22.080 68.799 0.734 1.00 7.48 ? 728 LEU A CG 1 ATOM 5993 C CD1 . LEU A 1 728 ? 20.779 69.039 1.484 1.00 10.11 ? 728 LEU A CD1 1 ATOM 5994 C CD2 . LEU A 1 728 ? 22.413 67.297 0.646 1.00 8.36 ? 728 LEU A CD2 1 ATOM 5995 N N . PHE A 1 729 ? 22.167 69.211 -3.871 1.00 6.94 ? 729 PHE A N 1 ATOM 5996 C CA . PHE A 1 729 ? 21.629 69.820 -5.071 1.00 7.46 ? 729 PHE A CA 1 ATOM 5997 C C . PHE A 1 729 ? 20.115 69.639 -5.001 1.00 7.48 ? 729 PHE A C 1 ATOM 5998 O O . PHE A 1 729 ? 19.624 68.512 -5.081 1.00 9.07 ? 729 PHE A O 1 ATOM 5999 C CB . PHE A 1 729 ? 22.169 69.043 -6.267 1.00 6.77 ? 729 PHE A CB 1 ATOM 6000 C CG . PHE A 1 729 ? 21.668 69.531 -7.608 1.00 6.71 ? 729 PHE A CG 1 ATOM 6001 C CD1 . PHE A 1 729 ? 21.344 70.874 -7.861 1.00 8.01 ? 729 PHE A CD1 1 ATOM 6002 C CD2 . PHE A 1 729 ? 21.591 68.615 -8.651 1.00 6.35 ? 729 PHE A CD2 1 ATOM 6003 C CE1 . PHE A 1 729 ? 20.928 71.287 -9.148 1.00 7.97 ? 729 PHE A CE1 1 ATOM 6004 C CE2 . PHE A 1 729 ? 21.166 69.026 -9.933 1.00 7.90 ? 729 PHE A CE2 1 ATOM 6005 C CZ . PHE A 1 729 ? 20.846 70.360 -10.171 1.00 8.39 ? 729 PHE A CZ 1 ATOM 6006 N N . LEU A 1 730 ? 19.408 70.759 -4.801 1.00 7.58 ? 730 LEU A N 1 ATOM 6007 C CA . LEU A 1 730 ? 17.952 70.699 -4.629 1.00 8.50 ? 730 LEU A CA 1 ATOM 6008 C C . LEU A 1 730 ? 17.320 71.685 -5.597 1.00 8.06 ? 730 LEU A C 1 ATOM 6009 O O . LEU A 1 730 ? 16.884 72.762 -5.182 1.00 8.65 ? 730 LEU A O 1 ATOM 6010 C CB . LEU A 1 730 ? 17.573 71.022 -3.177 1.00 8.32 ? 730 LEU A CB 1 ATOM 6011 C CG . LEU A 1 730 ? 17.988 69.917 -2.211 1.00 9.29 ? 730 LEU A CG 1 ATOM 6012 C CD1 . LEU A 1 730 ? 17.999 70.391 -0.784 1.00 11.65 ? 730 LEU A CD1 1 ATOM 6013 C CD2 . LEU A 1 730 ? 17.026 68.716 -2.358 1.00 13.50 ? 730 LEU A CD2 1 ATOM 6014 N N . PRO A 1 731 ? 17.316 71.361 -6.883 1.00 8.27 ? 731 PRO A N 1 ATOM 6015 C CA . PRO A 1 731 ? 16.896 72.350 -7.890 1.00 9.41 ? 731 PRO A CA 1 ATOM 6016 C C . PRO A 1 731 ? 15.413 72.664 -7.763 1.00 10.61 ? 731 PRO A C 1 ATOM 6017 O O . PRO A 1 731 ? 14.627 71.822 -7.319 1.00 9.60 ? 731 PRO A O 1 ATOM 6018 C CB . PRO A 1 731 ? 17.150 71.634 -9.207 1.00 10.11 ? 731 PRO A CB 1 ATOM 6019 C CG . PRO A 1 731 ? 17.139 70.147 -8.907 1.00 10.45 ? 731 PRO A CG 1 ATOM 6020 C CD . PRO A 1 731 ? 17.691 70.080 -7.507 1.00 8.62 ? 731 PRO A CD 1 ATOM 6021 N N . ASN A 1 732 ? 15.044 73.871 -8.191 1.00 11.27 ? 732 ASN A N 1 ATOM 6022 C CA . ASN A 1 732 ? 13.637 74.255 -8.267 1.00 13.47 ? 732 ASN A CA 1 ATOM 6023 C C . ASN A 1 732 ? 13.126 73.912 -9.659 1.00 13.12 ? 732 ASN A C 1 ATOM 6024 O O . ASN A 1 732 ? 12.726 74.794 -10.446 1.00 15.67 ? 732 ASN A O 1 ATOM 6025 C CB . ASN A 1 732 ? 13.480 75.740 -7.946 1.00 14.82 ? 732 ASN A CB 1 ATOM 6026 C CG . ASN A 1 732 ? 14.162 76.643 -8.957 1.00 17.05 ? 732 ASN A CG 1 ATOM 6027 O OD1 . ASN A 1 732 ? 15.134 76.262 -9.605 1.00 19.50 ? 732 ASN A OD1 1 ATOM 6028 N ND2 . ASN A 1 732 ? 13.642 77.875 -9.100 1.00 20.91 ? 732 ASN A ND2 1 ATOM 6029 N N . GLY A 1 733 ? 13.198 72.642 -10.002 1.00 11.12 ? 733 GLY A N 1 ATOM 6030 C CA . GLY A 1 733 ? 12.744 72.151 -11.286 1.00 12.11 ? 733 GLY A CA 1 ATOM 6031 C C . GLY A 1 733 ? 13.862 72.063 -12.312 1.00 10.96 ? 733 GLY A C 1 ATOM 6032 O O . GLY A 1 733 ? 15.023 72.409 -12.018 1.00 10.61 ? 733 GLY A O 1 ATOM 6033 N N . PRO A 1 734 ? 13.535 71.579 -13.511 1.00 10.20 ? 734 PRO A N 1 ATOM 6034 C CA . PRO A 1 734 ? 14.495 71.490 -14.618 1.00 11.24 ? 734 PRO A CA 1 ATOM 6035 C C . PRO A 1 734 ? 15.105 72.845 -14.938 1.00 11.05 ? 734 PRO A C 1 ATOM 6036 O O . PRO A 1 734 ? 14.532 73.903 -14.657 1.00 10.50 ? 734 PRO A O 1 ATOM 6037 C CB . PRO A 1 734 ? 13.643 70.991 -15.797 1.00 12.23 ? 734 PRO A CB 1 ATOM 6038 C CG . PRO A 1 734 ? 12.441 70.381 -15.161 1.00 12.79 ? 734 PRO A CG 1 ATOM 6039 C CD . PRO A 1 734 ? 12.204 71.027 -13.852 1.00 11.20 ? 734 PRO A CD 1 ATOM 6040 N N . ALA A 1 735 ? 16.298 72.783 -15.522 1.00 9.91 ? 735 ALA A N 1 ATOM 6041 C CA . ALA A 1 735 ? 17.035 73.972 -15.882 1.00 10.21 ? 735 ALA A CA 1 ATOM 6042 C C . ALA A 1 735 ? 16.338 74.798 -16.971 1.00 11.22 ? 735 ALA A C 1 ATOM 6043 O O . ALA A 1 735 ? 15.615 74.252 -17.809 1.00 12.00 ? 735 ALA A O 1 ATOM 6044 C CB . ALA A 1 735 ? 18.421 73.557 -16.327 1.00 10.28 ? 735 ALA A CB 1 ATOM 6045 N N . SER A 1 736 ? 16.573 76.099 -16.911 1.00 12.68 ? 736 SER A N 1 ATOM 6046 C CA . SER A 1 736 ? 16.017 77.076 -17.863 1.00 13.66 ? 736 SER A CA 1 ATOM 6047 C C . SER A 1 736 ? 17.154 77.623 -18.721 1.00 13.51 ? 736 SER A C 1 ATOM 6048 O O . SER A 1 736 ? 18.248 77.856 -18.201 1.00 11.99 ? 736 SER A O 1 ATOM 6049 C CB . SER A 1 736 ? 15.403 78.248 -17.087 1.00 14.94 ? 736 SER A CB 1 ATOM 6050 O OG . SER A 1 736 ? 14.484 77.791 -16.114 1.00 22.06 ? 736 SER A OG 1 ATOM 6051 N N . PRO A 1 737 ? 16.932 77.869 -20.006 1.00 14.94 ? 737 PRO A N 1 ATOM 6052 C CA . PRO A 1 737 ? 18.019 78.365 -20.868 1.00 15.49 ? 737 PRO A CA 1 ATOM 6053 C C . PRO A 1 737 ? 18.582 79.691 -20.377 1.00 15.81 ? 737 PRO A C 1 ATOM 6054 O O . PRO A 1 737 ? 17.826 80.549 -19.931 1.00 17.16 ? 737 PRO A O 1 ATOM 6055 C CB . PRO A 1 737 ? 17.361 78.531 -22.251 1.00 16.02 ? 737 PRO A CB 1 ATOM 6056 C CG . PRO A 1 737 ? 16.144 77.695 -22.186 1.00 16.87 ? 737 PRO A CG 1 ATOM 6057 C CD . PRO A 1 737 ? 15.675 77.651 -20.749 1.00 15.69 ? 737 PRO A CD 1 ATOM 6058 N N . VAL A 1 738 ? 19.907 79.837 -20.430 1.00 15.22 ? 738 VAL A N 1 ATOM 6059 C CA . VAL A 1 738 ? 20.535 81.141 -20.215 1.00 15.38 ? 738 VAL A CA 1 ATOM 6060 C C . VAL A 1 738 ? 20.139 82.033 -21.406 1.00 16.09 ? 738 VAL A C 1 ATOM 6061 O O . VAL A 1 738 ? 20.242 81.620 -22.570 1.00 16.37 ? 738 VAL A O 1 ATOM 6062 C CB . VAL A 1 738 ? 22.076 81.002 -20.087 1.00 13.79 ? 738 VAL A CB 1 ATOM 6063 C CG1 . VAL A 1 738 ? 22.753 82.384 -20.033 1.00 14.20 ? 738 VAL A CG1 1 ATOM 6064 C CG2 . VAL A 1 738 ? 22.460 80.142 -18.826 1.00 13.96 ? 738 VAL A CG2 1 ATOM 6065 N N . GLU A 1 739 ? 19.696 83.248 -21.092 1.00 18.01 ? 739 GLU A N 1 ATOM 6066 C CA . GLU A 1 739 ? 19.390 84.245 -22.115 1.00 18.97 ? 739 GLU A CA 1 ATOM 6067 C C . GLU A 1 739 ? 20.699 84.792 -22.666 1.00 18.27 ? 739 GLU A C 1 ATOM 6068 O O . GLU A 1 739 ? 21.485 85.371 -21.925 1.00 18.73 ? 739 GLU A O 1 ATOM 6069 C CB . GLU A 1 739 ? 18.623 85.395 -21.491 1.00 20.28 ? 739 GLU A CB 1 ATOM 6070 C CG . GLU A 1 739 ? 17.210 85.034 -21.084 1.00 24.92 ? 739 GLU A CG 1 ATOM 6071 C CD . GLU A 1 739 ? 16.364 86.269 -20.848 1.00 32.04 ? 739 GLU A CD 1 ATOM 6072 O OE1 . GLU A 1 739 ? 16.292 87.120 -21.771 1.00 34.21 ? 739 GLU A OE1 1 ATOM 6073 O OE2 . GLU A 1 739 ? 15.775 86.384 -19.745 1.00 36.20 ? 739 GLU A OE2 1 ATOM 6074 N N . LEU A 1 740 ? 20.944 84.558 -23.943 1.00 18.59 ? 740 LEU A N 1 ATOM 6075 C CA . LEU A 1 740 ? 22.263 84.833 -24.527 1.00 18.00 ? 740 LEU A CA 1 ATOM 6076 C C . LEU A 1 740 ? 22.418 86.203 -25.152 1.00 19.02 ? 740 LEU A C 1 ATOM 6077 O O . LEU A 1 740 ? 23.529 86.604 -25.415 1.00 19.13 ? 740 LEU A O 1 ATOM 6078 C CB . LEU A 1 740 ? 22.602 83.792 -25.588 1.00 17.92 ? 740 LEU A CB 1 ATOM 6079 C CG . LEU A 1 740 ? 22.557 82.330 -25.168 1.00 17.35 ? 740 LEU A CG 1 ATOM 6080 C CD1 . LEU A 1 740 ? 23.097 81.475 -26.301 1.00 17.25 ? 740 LEU A CD1 1 ATOM 6081 C CD2 . LEU A 1 740 ? 23.358 82.105 -23.872 1.00 18.87 ? 740 LEU A CD2 1 ATOM 6082 N N . GLY A 1 741 ? 21.310 86.898 -25.391 1.00 19.05 ? 741 GLY A N 1 ATOM 6083 C CA . GLY A 1 741 ? 21.350 88.172 -26.092 1.00 19.12 ? 741 GLY A CA 1 ATOM 6084 C C . GLY A 1 741 ? 21.896 87.945 -27.497 1.00 18.83 ? 741 GLY A C 1 ATOM 6085 O O . GLY A 1 741 ? 21.539 86.973 -28.156 1.00 19.33 ? 741 GLY A O 1 ATOM 6086 N N A GLN A 1 742 ? 22.799 88.829 -27.926 0.50 18.35 ? 742 GLN A N 1 ATOM 6087 N N B GLN A 1 742 ? 22.730 88.862 -27.979 0.50 18.40 ? 742 GLN A N 1 ATOM 6088 C CA A GLN A 1 742 ? 23.423 88.727 -29.244 0.50 17.27 ? 742 GLN A CA 1 ATOM 6089 C CA B GLN A 1 742 ? 23.416 88.659 -29.254 0.50 17.38 ? 742 GLN A CA 1 ATOM 6090 C C A GLN A 1 742 ? 24.952 88.646 -29.110 0.50 16.02 ? 742 GLN A C 1 ATOM 6091 C C B GLN A 1 742 ? 24.908 88.680 -28.924 0.50 16.09 ? 742 GLN A C 1 ATOM 6092 O O A GLN A 1 742 ? 25.655 89.607 -29.419 0.50 15.68 ? 742 GLN A O 1 ATOM 6093 O O B GLN A 1 742 ? 25.520 89.753 -28.798 0.50 15.48 ? 742 GLN A O 1 ATOM 6094 C CB A GLN A 1 742 ? 23.049 89.943 -30.097 0.50 18.22 ? 742 GLN A CB 1 ATOM 6095 C CB B GLN A 1 742 ? 23.031 89.734 -30.285 0.50 17.99 ? 742 GLN A CB 1 ATOM 6096 C CG A GLN A 1 742 ? 23.175 89.690 -31.585 0.50 19.79 ? 742 GLN A CG 1 ATOM 6097 C CG B GLN A 1 742 ? 21.513 89.858 -30.482 0.50 18.27 ? 742 GLN A CG 1 ATOM 6098 C CD A GLN A 1 742 ? 22.452 90.729 -32.436 0.50 23.55 ? 742 GLN A CD 1 ATOM 6099 C CD B GLN A 1 742 ? 21.118 90.998 -31.385 0.50 19.19 ? 742 GLN A CD 1 ATOM 6100 O OE1 A GLN A 1 742 ? 22.094 91.813 -31.953 0.50 25.48 ? 742 GLN A OE1 1 ATOM 6101 O OE1 B GLN A 1 742 ? 21.316 90.939 -32.601 0.50 20.84 ? 742 GLN A OE1 1 ATOM 6102 N NE2 A GLN A 1 742 ? 22.233 90.398 -33.705 0.50 23.69 ? 742 GLN A NE2 1 ATOM 6103 N NE2 B GLN A 1 742 ? 20.536 92.034 -30.801 0.50 22.31 ? 742 GLN A NE2 1 ATOM 6104 N N . PRO A 1 743 ? 25.480 87.503 -28.675 1.00 14.46 ? 743 PRO A N 1 ATOM 6105 C CA . PRO A 1 743 ? 26.883 87.462 -28.237 1.00 12.78 ? 743 PRO A CA 1 ATOM 6106 C C . PRO A 1 743 ? 27.893 87.656 -29.376 1.00 12.98 ? 743 PRO A C 1 ATOM 6107 O O . PRO A 1 743 ? 27.603 87.413 -30.566 1.00 13.88 ? 743 PRO A O 1 ATOM 6108 C CB . PRO A 1 743 ? 27.011 86.091 -27.569 1.00 13.09 ? 743 PRO A CB 1 ATOM 6109 C CG . PRO A 1 743 ? 25.988 85.254 -28.226 1.00 12.94 ? 743 PRO A CG 1 ATOM 6110 C CD . PRO A 1 743 ? 24.850 86.164 -28.678 1.00 14.37 ? 743 PRO A CD 1 ATOM 6111 N N . VAL A 1 744 ? 29.074 88.136 -28.981 1.00 10.76 ? 744 VAL A N 1 ATOM 6112 C CA . VAL A 1 744 ? 30.181 88.341 -29.897 1.00 9.97 ? 744 VAL A CA 1 ATOM 6113 C C . VAL A 1 744 ? 30.865 87.003 -30.109 1.00 8.96 ? 744 VAL A C 1 ATOM 6114 O O . VAL A 1 744 ? 31.189 86.291 -29.134 1.00 8.77 ? 744 VAL A O 1 ATOM 6115 C CB . VAL A 1 744 ? 31.166 89.366 -29.331 1.00 10.59 ? 744 VAL A CB 1 ATOM 6116 C CG1 . VAL A 1 744 ? 32.339 89.547 -30.238 1.00 10.73 ? 744 VAL A CG1 1 ATOM 6117 C CG2 . VAL A 1 744 ? 30.437 90.736 -29.055 1.00 12.50 ? 744 VAL A CG2 1 ATOM 6118 N N . VAL A 1 745 ? 31.067 86.662 -31.367 1.00 7.94 ? 745 VAL A N 1 ATOM 6119 C CA . VAL A 1 745 ? 31.692 85.399 -31.752 1.00 7.43 ? 745 VAL A CA 1 ATOM 6120 C C . VAL A 1 745 ? 32.974 85.652 -32.490 1.00 8.63 ? 745 VAL A C 1 ATOM 6121 O O . VAL A 1 745 ? 33.009 86.472 -33.426 1.00 8.38 ? 745 VAL A O 1 ATOM 6122 C CB . VAL A 1 745 ? 30.727 84.568 -32.646 1.00 7.74 ? 745 VAL A CB 1 ATOM 6123 C CG1 . VAL A 1 745 ? 31.447 83.292 -33.128 1.00 9.38 ? 745 VAL A CG1 1 ATOM 6124 C CG2 . VAL A 1 745 ? 29.407 84.280 -31.906 1.00 8.10 ? 745 VAL A CG2 1 ATOM 6125 N N . LEU A 1 746 ? 34.049 84.985 -32.086 1.00 7.95 ? 746 LEU A N 1 ATOM 6126 C CA . LEU A 1 746 ? 35.328 85.146 -32.717 1.00 7.85 ? 746 LEU A CA 1 ATOM 6127 C C . LEU A 1 746 ? 35.758 83.832 -33.368 1.00 8.44 ? 746 LEU A C 1 ATOM 6128 O O . LEU A 1 746 ? 35.867 82.812 -32.688 1.00 7.93 ? 746 LEU A O 1 ATOM 6129 C CB . LEU A 1 746 ? 36.367 85.595 -31.679 1.00 8.56 ? 746 LEU A CB 1 ATOM 6130 C CG . LEU A 1 746 ? 37.831 85.572 -32.108 1.00 11.21 ? 746 LEU A CG 1 ATOM 6131 C CD1 . LEU A 1 746 ? 38.137 86.636 -33.168 1.00 14.25 ? 746 LEU A CD1 1 ATOM 6132 C CD2 . LEU A 1 746 ? 38.743 85.695 -30.893 1.00 12.19 ? 746 LEU A CD2 1 ATOM 6133 N N . VAL A 1 747 ? 36.035 83.847 -34.655 1.00 7.88 ? 747 VAL A N 1 ATOM 6134 C CA . VAL A 1 747 ? 36.432 82.657 -35.401 1.00 7.94 ? 747 VAL A CA 1 ATOM 6135 C C . VAL A 1 747 ? 37.886 82.812 -35.809 1.00 9.09 ? 747 VAL A C 1 ATOM 6136 O O . VAL A 1 747 ? 38.255 83.807 -36.448 1.00 9.55 ? 747 VAL A O 1 ATOM 6137 C CB . VAL A 1 747 ? 35.552 82.478 -36.661 1.00 8.75 ? 747 VAL A CB 1 ATOM 6138 C CG1 . VAL A 1 747 ? 35.942 81.198 -37.384 1.00 9.51 ? 747 VAL A CG1 1 ATOM 6139 C CG2 . VAL A 1 747 ? 34.098 82.520 -36.281 1.00 8.48 ? 747 VAL A CG2 1 ATOM 6140 N N . THR A 1 748 ? 38.747 81.873 -35.445 1.00 8.64 ? 748 THR A N 1 ATOM 6141 C CA . THR A 1 748 ? 40.122 81.899 -35.885 1.00 10.01 ? 748 THR A CA 1 ATOM 6142 C C . THR A 1 748 ? 40.335 80.675 -36.745 1.00 10.18 ? 748 THR A C 1 ATOM 6143 O O . THR A 1 748 ? 39.980 79.559 -36.328 1.00 11.53 ? 748 THR A O 1 ATOM 6144 C CB . THR A 1 748 ? 41.053 81.942 -34.663 1.00 11.48 ? 748 THR A CB 1 ATOM 6145 O OG1 . THR A 1 748 ? 40.810 83.151 -33.910 1.00 13.47 ? 748 THR A OG1 1 ATOM 6146 C CG2 . THR A 1 748 ? 42.508 82.067 -35.076 1.00 13.47 ? 748 THR A CG2 1 ATOM 6147 N N . LYS A 1 749 ? 40.862 80.862 -37.953 1.00 10.09 ? 749 LYS A N 1 ATOM 6148 C CA . LYS A 1 749 ? 40.983 79.750 -38.874 1.00 10.20 ? 749 LYS A CA 1 ATOM 6149 C C . LYS A 1 749 ? 42.421 79.598 -39.291 1.00 10.46 ? 749 LYS A C 1 ATOM 6150 O O . LYS A 1 749 ? 43.017 80.533 -39.860 1.00 10.76 ? 749 LYS A O 1 ATOM 6151 C CB . LYS A 1 749 ? 40.127 79.964 -40.118 1.00 11.10 ? 749 LYS A CB 1 ATOM 6152 C CG . LYS A 1 749 ? 40.299 78.846 -41.127 1.00 15.01 ? 749 LYS A CG 1 ATOM 6153 C CD . LYS A 1 749 ? 39.399 79.058 -42.329 1.00 19.98 ? 749 LYS A CD 1 ATOM 6154 C CE . LYS A 1 749 ? 39.878 78.276 -43.536 1.00 24.31 ? 749 LYS A CE 1 ATOM 6155 N NZ . LYS A 1 749 ? 39.199 78.829 -44.745 1.00 29.20 ? 749 LYS A NZ 1 ATOM 6156 N N . GLY A 1 750 ? 42.985 78.428 -39.012 1.00 9.87 ? 750 GLY A N 1 ATOM 6157 C CA . GLY A 1 750 ? 44.381 78.183 -39.263 1.00 11.31 ? 750 GLY A CA 1 ATOM 6158 C C . GLY A 1 750 ? 44.585 76.807 -39.831 1.00 12.22 ? 750 GLY A C 1 ATOM 6159 O O . GLY A 1 750 ? 43.692 75.951 -39.727 1.00 13.18 ? 750 GLY A O 1 ATOM 6160 N N . LYS A 1 751 ? 45.765 76.595 -40.404 1.00 11.96 ? 751 LYS A N 1 ATOM 6161 C CA . LYS A 1 751 ? 46.076 75.313 -41.018 1.00 12.48 ? 751 LYS A CA 1 ATOM 6162 C C . LYS A 1 751 ? 46.159 74.221 -39.948 1.00 11.67 ? 751 LYS A C 1 ATOM 6163 O O . LYS A 1 751 ? 45.766 73.076 -40.203 1.00 11.84 ? 751 LYS A O 1 ATOM 6164 C CB . LYS A 1 751 ? 47.402 75.408 -41.761 1.00 13.90 ? 751 LYS A CB 1 ATOM 6165 C CG . LYS A 1 751 ? 47.732 74.183 -42.588 1.00 18.97 ? 751 LYS A CG 1 ATOM 6166 C CD . LYS A 1 751 ? 47.591 74.454 -44.089 1.00 25.76 ? 751 LYS A CD 1 ATOM 6167 C CE . LYS A 1 751 ? 48.377 73.397 -44.843 1.00 30.03 ? 751 LYS A CE 1 ATOM 6168 N NZ . LYS A 1 751 ? 49.725 73.204 -44.209 1.00 32.90 ? 751 LYS A NZ 1 ATOM 6169 N N . LEU A 1 752 ? 46.721 74.577 -38.791 1.00 10.35 ? 752 LEU A N 1 ATOM 6170 C CA . LEU A 1 752 ? 46.979 73.621 -37.703 1.00 9.88 ? 752 LEU A CA 1 ATOM 6171 C C . LEU A 1 752 ? 45.905 73.630 -36.645 1.00 10.56 ? 752 LEU A C 1 ATOM 6172 O O . LEU A 1 752 ? 45.659 72.592 -36.023 1.00 9.73 ? 752 LEU A O 1 ATOM 6173 C CB . LEU A 1 752 ? 48.304 73.933 -37.022 1.00 9.83 ? 752 LEU A CB 1 ATOM 6174 C CG . LEU A 1 752 ? 49.543 73.794 -37.924 1.00 11.82 ? 752 LEU A CG 1 ATOM 6175 C CD1 . LEU A 1 752 ? 50.809 73.945 -37.123 1.00 12.37 ? 752 LEU A CD1 1 ATOM 6176 C CD2 . LEU A 1 752 ? 49.573 72.523 -38.778 1.00 14.38 ? 752 LEU A CD2 1 ATOM 6177 N N . GLU A 1 753 ? 45.281 74.788 -36.404 1.00 10.17 ? 753 GLU A N 1 ATOM 6178 C CA . GLU A 1 753 ? 44.314 74.920 -35.335 1.00 10.55 ? 753 GLU A CA 1 ATOM 6179 C C . GLU A 1 753 ? 43.329 76.008 -35.715 1.00 10.27 ? 753 GLU A C 1 ATOM 6180 O O . GLU A 1 753 ? 43.728 77.108 -36.150 1.00 10.47 ? 753 GLU A O 1 ATOM 6181 C CB . GLU A 1 753 ? 45.025 75.294 -34.029 1.00 10.49 ? 753 GLU A CB 1 ATOM 6182 C CG . GLU A 1 753 ? 44.075 75.408 -32.838 1.00 13.01 ? 753 GLU A CG 1 ATOM 6183 C CD . GLU A 1 753 ? 44.724 76.041 -31.617 1.00 15.17 ? 753 GLU A CD 1 ATOM 6184 O OE1 . GLU A 1 753 ? 44.869 77.285 -31.580 1.00 23.49 ? 753 GLU A OE1 1 ATOM 6185 O OE2 . GLU A 1 753 ? 45.070 75.287 -30.697 1.00 21.84 ? 753 GLU A OE2 1 ATOM 6186 N N . SER A 1 754 ? 42.065 75.699 -35.552 1.00 8.16 ? 754 SER A N 1 ATOM 6187 C CA . SER A 1 754 ? 40.990 76.666 -35.698 1.00 8.61 ? 754 SER A CA 1 ATOM 6188 C C . SER A 1 754 ? 40.138 76.703 -34.468 1.00 8.35 ? 754 SER A C 1 ATOM 6189 O O . SER A 1 754 ? 40.157 75.741 -33.687 1.00 8.95 ? 754 SER A O 1 ATOM 6190 C CB . SER A 1 754 ? 40.127 76.324 -36.892 1.00 9.15 ? 754 SER A CB 1 ATOM 6191 O OG . SER A 1 754 ? 40.906 76.463 -38.080 1.00 9.85 ? 754 SER A OG 1 ATOM 6192 N N . SER A 1 755 ? 39.376 77.770 -34.253 1.00 8.27 ? 755 SER A N 1 ATOM 6193 C CA A SER A 1 755 ? 38.540 77.879 -33.060 0.50 8.75 ? 755 SER A CA 1 ATOM 6194 C CA B SER A 1 755 ? 38.487 77.819 -33.094 0.50 8.94 ? 755 SER A CA 1 ATOM 6195 C C . SER A 1 755 ? 37.343 78.779 -33.273 1.00 8.40 ? 755 SER A C 1 ATOM 6196 O O . SER A 1 755 ? 37.408 79.697 -34.109 1.00 8.59 ? 755 SER A O 1 ATOM 6197 C CB A SER A 1 755 ? 39.362 78.440 -31.905 0.50 9.69 ? 755 SER A CB 1 ATOM 6198 C CB B SER A 1 755 ? 39.247 78.182 -31.813 0.50 10.34 ? 755 SER A CB 1 ATOM 6199 O OG A SER A 1 755 ? 40.003 79.637 -32.281 0.50 11.69 ? 755 SER A OG 1 ATOM 6200 O OG B SER A 1 755 ? 39.658 79.530 -31.809 0.50 12.10 ? 755 SER A OG 1 ATOM 6201 N N . VAL A 1 756 ? 36.309 78.563 -32.491 1.00 7.18 ? 756 VAL A N 1 ATOM 6202 C CA . VAL A 1 756 ? 35.188 79.469 -32.398 1.00 7.48 ? 756 VAL A CA 1 ATOM 6203 C C . VAL A 1 756 ? 35.048 79.785 -30.919 1.00 7.72 ? 756 VAL A C 1 ATOM 6204 O O . VAL A 1 756 ? 34.889 78.856 -30.092 1.00 7.74 ? 756 VAL A O 1 ATOM 6205 C CB . VAL A 1 756 ? 33.911 78.857 -32.956 1.00 8.12 ? 756 VAL A CB 1 ATOM 6206 C CG1 . VAL A 1 756 ? 32.762 79.835 -32.800 1.00 8.86 ? 756 VAL A CG1 1 ATOM 6207 C CG2 . VAL A 1 756 ? 34.147 78.463 -34.426 1.00 10.80 ? 756 VAL A CG2 1 ATOM 6208 N N . SER A 1 757 ? 35.075 81.059 -30.566 1.00 7.36 ? 757 SER A N 1 ATOM 6209 C CA . SER A 1 757 ? 34.921 81.478 -29.177 1.00 7.78 ? 757 SER A CA 1 ATOM 6210 C C . SER A 1 757 ? 33.774 82.438 -29.066 1.00 7.57 ? 757 SER A C 1 ATOM 6211 O O . SER A 1 757 ? 33.639 83.304 -29.945 1.00 8.63 ? 757 SER A O 1 ATOM 6212 C CB . SER A 1 757 ? 36.180 82.197 -28.701 1.00 8.73 ? 757 SER A CB 1 ATOM 6213 O OG . SER A 1 757 ? 37.289 81.328 -28.884 1.00 12.05 ? 757 SER A OG 1 ATOM 6214 N N . VAL A 1 758 ? 32.979 82.352 -28.011 1.00 7.47 ? 758 VAL A N 1 ATOM 6215 C CA . VAL A 1 758 ? 31.837 83.233 -27.834 1.00 7.94 ? 758 VAL A CA 1 ATOM 6216 C C . VAL A 1 758 ? 31.744 83.719 -26.405 1.00 7.88 ? 758 VAL A C 1 ATOM 6217 O O . VAL A 1 758 ? 31.898 82.913 -25.478 1.00 7.63 ? 758 VAL A O 1 ATOM 6218 C CB . VAL A 1 758 ? 30.532 82.573 -28.345 1.00 8.62 ? 758 VAL A CB 1 ATOM 6219 C CG1 . VAL A 1 758 ? 30.234 81.263 -27.622 1.00 8.66 ? 758 VAL A CG1 1 ATOM 6220 C CG2 . VAL A 1 758 ? 29.382 83.540 -28.169 1.00 10.76 ? 758 VAL A CG2 1 ATOM 6221 N N . GLY A 1 759 ? 31.467 85.005 -26.217 1.00 8.20 ? 759 GLY A N 1 ATOM 6222 C CA . GLY A 1 759 ? 31.353 85.576 -24.877 1.00 8.35 ? 759 GLY A CA 1 ATOM 6223 C C . GLY A 1 759 ? 29.903 85.504 -24.449 1.00 9.47 ? 759 GLY A C 1 ATOM 6224 O O . GLY A 1 759 ? 29.090 86.329 -24.852 1.00 9.63 ? 759 GLY A O 1 ATOM 6225 N N . LEU A 1 760 ? 29.551 84.487 -23.686 1.00 10.39 ? 760 LEU A N 1 ATOM 6226 C CA . LEU A 1 760 ? 28.192 84.329 -23.153 1.00 11.02 ? 760 LEU A CA 1 ATOM 6227 C C . LEU A 1 760 ? 28.114 84.899 -21.741 1.00 11.67 ? 760 LEU A C 1 ATOM 6228 O O . LEU A 1 760 ? 29.154 85.080 -21.076 1.00 12.11 ? 760 LEU A O 1 ATOM 6229 C CB . LEU A 1 760 ? 27.854 82.826 -23.114 1.00 11.72 ? 760 LEU A CB 1 ATOM 6230 C CG . LEU A 1 760 ? 27.998 82.113 -24.449 1.00 11.08 ? 760 LEU A CG 1 ATOM 6231 C CD1 . LEU A 1 760 ? 27.753 80.629 -24.301 1.00 14.46 ? 760 LEU A CD1 1 ATOM 6232 C CD2 . LEU A 1 760 ? 27.049 82.699 -25.502 1.00 12.77 ? 760 LEU A CD2 1 ATOM 6233 N N . PRO A 1 761 ? 26.914 85.153 -21.230 1.00 12.66 ? 761 PRO A N 1 ATOM 6234 C CA . PRO A 1 761 ? 26.823 85.532 -19.816 1.00 12.39 ? 761 PRO A CA 1 ATOM 6235 C C . PRO A 1 761 ? 27.405 84.408 -18.945 1.00 12.97 ? 761 PRO A C 1 ATOM 6236 O O . PRO A 1 761 ? 26.968 83.246 -19.032 1.00 13.26 ? 761 PRO A O 1 ATOM 6237 C CB . PRO A 1 761 ? 25.315 85.711 -19.585 1.00 13.57 ? 761 PRO A CB 1 ATOM 6238 C CG . PRO A 1 761 ? 24.803 86.004 -20.969 1.00 14.09 ? 761 PRO A CG 1 ATOM 6239 C CD . PRO A 1 761 ? 25.592 85.124 -21.893 1.00 12.52 ? 761 PRO A CD 1 ATOM 6240 N N . SER A 1 762 ? 28.401 84.779 -18.147 1.00 12.18 ? 762 SER A N 1 ATOM 6241 C CA . SER A 1 762 ? 29.093 83.896 -17.215 1.00 11.30 ? 762 SER A CA 1 ATOM 6242 C C . SER A 1 762 ? 30.052 82.904 -17.845 1.00 10.08 ? 762 SER A C 1 ATOM 6243 O O . SER A 1 762 ? 30.722 82.185 -17.099 1.00 9.82 ? 762 SER A O 1 ATOM 6244 C CB . SER A 1 762 ? 28.113 83.083 -16.392 1.00 12.80 ? 762 SER A CB 1 ATOM 6245 O OG . SER A 1 762 ? 27.235 83.923 -15.675 1.00 15.96 ? 762 SER A OG 1 ATOM 6246 N N . VAL A 1 763 ? 30.119 82.802 -19.172 1.00 9.61 ? 763 VAL A N 1 ATOM 6247 C CA . VAL A 1 763 ? 31.009 81.822 -19.765 1.00 9.19 ? 763 VAL A CA 1 ATOM 6248 C C . VAL A 1 763 ? 31.617 82.308 -21.057 1.00 8.39 ? 763 VAL A C 1 ATOM 6249 O O . VAL A 1 763 ? 30.875 82.673 -21.970 1.00 9.46 ? 763 VAL A O 1 ATOM 6250 C CB . VAL A 1 763 ? 30.259 80.494 -20.090 1.00 9.94 ? 763 VAL A CB 1 ATOM 6251 C CG1 . VAL A 1 763 ? 31.225 79.462 -20.632 1.00 11.14 ? 763 VAL A CG1 1 ATOM 6252 C CG2 . VAL A 1 763 ? 29.553 79.887 -18.887 1.00 12.53 ? 763 VAL A CG2 1 ATOM 6253 N N . VAL A 1 764 ? 32.929 82.261 -21.177 1.00 6.54 ? 764 VAL A N 1 ATOM 6254 C CA . VAL A 1 764 ? 33.533 82.385 -22.497 1.00 7.19 ? 764 VAL A CA 1 ATOM 6255 C C . VAL A 1 764 ? 33.729 80.942 -22.966 1.00 7.24 ? 764 VAL A C 1 ATOM 6256 O O . VAL A 1 764 ? 34.500 80.174 -22.376 1.00 7.29 ? 764 VAL A O 1 ATOM 6257 C CB . VAL A 1 764 ? 34.876 83.119 -22.513 1.00 7.29 ? 764 VAL A CB 1 ATOM 6258 C CG1 . VAL A 1 764 ? 35.424 83.215 -23.955 1.00 9.36 ? 764 VAL A CG1 1 ATOM 6259 C CG2 . VAL A 1 764 ? 34.715 84.516 -21.937 1.00 9.40 ? 764 VAL A CG2 1 ATOM 6260 N N . HIS A 1 765 ? 33.018 80.578 -24.019 1.00 6.89 ? 765 HIS A N 1 ATOM 6261 C CA . HIS A 1 765 ? 32.931 79.180 -24.482 1.00 6.49 ? 765 HIS A CA 1 ATOM 6262 C C . HIS A 1 765 ? 33.738 79.088 -25.747 1.00 7.05 ? 765 HIS A C 1 ATOM 6263 O O . HIS A 1 765 ? 33.558 79.919 -26.663 1.00 7.83 ? 765 HIS A O 1 ATOM 6264 C CB . HIS A 1 765 ? 31.466 78.849 -24.714 1.00 7.82 ? 765 HIS A CB 1 ATOM 6265 C CG . HIS A 1 765 ? 31.213 77.561 -25.416 1.00 8.47 ? 765 HIS A CG 1 ATOM 6266 N ND1 . HIS A 1 765 ? 31.395 76.337 -24.811 1.00 6.84 ? 765 HIS A ND1 1 ATOM 6267 C CD2 . HIS A 1 765 ? 30.697 77.304 -26.644 1.00 10.71 ? 765 HIS A CD2 1 ATOM 6268 C CE1 . HIS A 1 765 ? 31.049 75.376 -25.664 1.00 9.56 ? 765 HIS A CE1 1 ATOM 6269 N NE2 . HIS A 1 765 ? 30.631 75.943 -26.789 1.00 10.92 ? 765 HIS A NE2 1 ATOM 6270 N N . GLN A 1 766 ? 34.618 78.113 -25.845 1.00 6.10 ? 766 GLN A N 1 ATOM 6271 C CA A GLN A 1 766 ? 35.532 77.975 -26.970 0.50 6.67 ? 766 GLN A CA 1 ATOM 6272 C CA B GLN A 1 766 ? 35.498 77.977 -26.981 0.50 6.73 ? 766 GLN A CA 1 ATOM 6273 C C . GLN A 1 766 ? 35.516 76.538 -27.471 1.00 7.18 ? 766 GLN A C 1 ATOM 6274 O O . GLN A 1 766 ? 35.632 75.600 -26.663 1.00 7.67 ? 766 GLN A O 1 ATOM 6275 C CB A GLN A 1 766 ? 36.972 78.301 -26.568 0.50 7.28 ? 766 GLN A CB 1 ATOM 6276 C CB B GLN A 1 766 ? 36.908 78.395 -26.602 0.50 7.20 ? 766 GLN A CB 1 ATOM 6277 C CG A GLN A 1 766 ? 37.159 79.649 -25.866 0.50 7.29 ? 766 GLN A CG 1 ATOM 6278 C CG B GLN A 1 766 ? 37.918 78.300 -27.713 0.50 7.85 ? 766 GLN A CG 1 ATOM 6279 C CD A GLN A 1 766 ? 38.152 79.607 -24.670 0.50 13.80 ? 766 GLN A CD 1 ATOM 6280 C CD B GLN A 1 766 ? 39.315 78.697 -27.280 0.50 10.39 ? 766 GLN A CD 1 ATOM 6281 O OE1 A GLN A 1 766 ? 39.308 79.241 -24.846 0.50 11.82 ? 766 GLN A OE1 1 ATOM 6282 O OE1 B GLN A 1 766 ? 39.684 78.510 -26.120 0.50 11.86 ? 766 GLN A OE1 1 ATOM 6283 N NE2 A GLN A 1 766 ? 37.684 79.983 -23.461 0.50 13.80 ? 766 GLN A NE2 1 ATOM 6284 N NE2 B GLN A 1 766 ? 40.097 79.249 -28.213 0.50 10.41 ? 766 GLN A NE2 1 ATOM 6285 N N . THR A 1 767 ? 35.386 76.359 -28.776 1.00 6.89 ? 767 THR A N 1 ATOM 6286 C CA . THR A 1 767 ? 35.548 75.051 -29.431 1.00 7.79 ? 767 THR A CA 1 ATOM 6287 C C . THR A 1 767 ? 36.790 75.125 -30.261 1.00 8.17 ? 767 THR A C 1 ATOM 6288 O O . THR A 1 767 ? 36.891 76.035 -31.106 1.00 8.69 ? 767 THR A O 1 ATOM 6289 C CB . THR A 1 767 ? 34.356 74.769 -30.337 1.00 8.50 ? 767 THR A CB 1 ATOM 6290 O OG1 . THR A 1 767 ? 33.158 74.843 -29.557 1.00 11.90 ? 767 THR A OG1 1 ATOM 6291 C CG2 . THR A 1 767 ? 34.400 73.332 -30.877 1.00 9.95 ? 767 THR A CG2 1 ATOM 6292 N N . ILE A 1 768 ? 37.747 74.229 -30.042 1.00 8.22 ? 768 ILE A N 1 ATOM 6293 C CA . ILE A 1 768 ? 39.044 74.234 -30.698 1.00 8.15 ? 768 ILE A CA 1 ATOM 6294 C C . ILE A 1 768 ? 39.202 72.968 -31.526 1.00 9.42 ? 768 ILE A C 1 ATOM 6295 O O . ILE A 1 768 ? 38.931 71.868 -31.033 1.00 10.04 ? 768 ILE A O 1 ATOM 6296 C CB . ILE A 1 768 ? 40.190 74.352 -29.666 1.00 8.04 ? 768 ILE A CB 1 ATOM 6297 C CG1 . ILE A 1 768 ? 40.019 75.589 -28.796 1.00 11.19 ? 768 ILE A CG1 1 ATOM 6298 C CG2 . ILE A 1 768 ? 41.549 74.419 -30.380 1.00 12.14 ? 768 ILE A CG2 1 ATOM 6299 C CD1 . ILE A 1 768 ? 40.870 75.503 -27.545 1.00 13.20 ? 768 ILE A CD1 1 ATOM 6300 N N . MET A 1 769 ? 39.662 73.134 -32.748 1.00 8.56 ? 769 MET A N 1 ATOM 6301 C CA A MET A 1 769 ? 39.812 72.034 -33.689 0.50 9.32 ? 769 MET A CA 1 ATOM 6302 C CA B MET A 1 769 ? 39.790 72.043 -33.706 0.50 9.81 ? 769 MET A CA 1 ATOM 6303 C C . MET A 1 769 ? 41.251 71.915 -34.127 1.00 9.82 ? 769 MET A C 1 ATOM 6304 O O . MET A 1 769 ? 41.857 72.882 -34.607 1.00 8.92 ? 769 MET A O 1 ATOM 6305 C CB A MET A 1 769 ? 38.956 72.303 -34.910 0.50 9.81 ? 769 MET A CB 1 ATOM 6306 C CB B MET A 1 769 ? 38.894 72.324 -34.924 0.50 10.18 ? 769 MET A CB 1 ATOM 6307 C CG A MET A 1 769 ? 37.527 72.482 -34.563 0.50 9.07 ? 769 MET A CG 1 ATOM 6308 C CG B MET A 1 769 ? 37.413 72.149 -34.627 0.50 11.22 ? 769 MET A CG 1 ATOM 6309 S SD A MET A 1 769 ? 36.646 72.866 -36.044 0.50 12.11 ? 769 MET A SD 1 ATOM 6310 S SD B MET A 1 769 ? 36.292 73.218 -35.587 0.50 13.43 ? 769 MET A SD 1 ATOM 6311 C CE A MET A 1 769 ? 36.953 71.496 -37.073 0.50 10.78 ? 769 MET A CE 1 ATOM 6312 C CE B MET A 1 769 ? 36.541 74.809 -34.738 0.50 12.38 ? 769 MET A CE 1 ATOM 6313 N N . ARG A 1 770 ? 41.803 70.722 -33.975 1.00 10.00 ? 770 ARG A N 1 ATOM 6314 C CA . ARG A 1 770 ? 43.174 70.467 -34.382 1.00 11.22 ? 770 ARG A CA 1 ATOM 6315 C C . ARG A 1 770 ? 43.279 69.269 -35.309 1.00 12.27 ? 770 ARG A C 1 ATOM 6316 O O . ARG A 1 770 ? 44.381 68.795 -35.566 1.00 13.73 ? 770 ARG A O 1 ATOM 6317 C CB . ARG A 1 770 ? 44.072 70.277 -33.169 1.00 11.89 ? 770 ARG A CB 1 ATOM 6318 C CG . ARG A 1 770 ? 44.171 71.500 -32.303 1.00 13.48 ? 770 ARG A CG 1 ATOM 6319 C CD . ARG A 1 770 ? 45.003 71.284 -31.046 1.00 17.16 ? 770 ARG A CD 1 ATOM 6320 N NE . ARG A 1 770 ? 44.872 72.368 -30.067 1.00 24.39 ? 770 ARG A NE 1 ATOM 6321 C CZ . ARG A 1 770 ? 44.172 72.269 -28.931 1.00 26.31 ? 770 ARG A CZ 1 ATOM 6322 N NH1 . ARG A 1 770 ? 43.545 71.132 -28.635 1.00 27.47 ? 770 ARG A NH1 1 ATOM 6323 N NH2 . ARG A 1 770 ? 44.107 73.300 -28.083 1.00 29.34 ? 770 ARG A NH2 1 ATOM 6324 N N . GLY A 1 771 ? 42.139 68.815 -35.804 1.00 12.59 ? 771 GLY A N 1 ATOM 6325 C CA . GLY A 1 771 ? 42.121 67.767 -36.810 1.00 15.76 ? 771 GLY A CA 1 ATOM 6326 C C . GLY A 1 771 ? 41.557 66.442 -36.360 1.00 16.72 ? 771 GLY A C 1 ATOM 6327 O O . GLY A 1 771 ? 41.494 65.498 -37.157 1.00 18.81 ? 771 GLY A O 1 ATOM 6328 N N . GLY A 1 772 ? 41.169 66.347 -35.088 1.00 16.61 ? 772 GLY A N 1 ATOM 6329 C CA . GLY A 1 772 ? 40.517 65.160 -34.513 1.00 15.93 ? 772 GLY A CA 1 ATOM 6330 C C . GLY A 1 772 ? 39.342 65.636 -33.659 1.00 14.17 ? 772 GLY A C 1 ATOM 6331 O O . GLY A 1 772 ? 38.738 66.644 -33.992 1.00 13.66 ? 772 GLY A O 1 ATOM 6332 N N . ALA A 1 773 ? 39.002 64.941 -32.565 1.00 12.79 ? 773 ALA A N 1 ATOM 6333 C CA . ALA A 1 773 ? 37.908 65.381 -31.704 1.00 11.13 ? 773 ALA A CA 1 ATOM 6334 C C . ALA A 1 773 ? 38.147 66.810 -31.211 1.00 9.81 ? 773 ALA A C 1 ATOM 6335 O O . ALA A 1 773 ? 39.256 67.138 -30.822 1.00 10.34 ? 773 ALA A O 1 ATOM 6336 C CB . ALA A 1 773 ? 37.793 64.464 -30.511 1.00 11.32 ? 773 ALA A CB 1 ATOM 6337 N N . PRO A 1 774 ? 37.126 67.656 -31.219 1.00 9.59 ? 774 PRO A N 1 ATOM 6338 C CA . PRO A 1 774 ? 37.331 69.011 -30.702 1.00 9.41 ? 774 PRO A CA 1 ATOM 6339 C C . PRO A 1 774 ? 37.657 69.051 -29.218 1.00 8.85 ? 774 PRO A C 1 ATOM 6340 O O . PRO A 1 774 ? 37.364 68.103 -28.449 1.00 7.67 ? 774 PRO A O 1 ATOM 6341 C CB . PRO A 1 774 ? 35.975 69.708 -30.932 1.00 10.89 ? 774 PRO A CB 1 ATOM 6342 C CG . PRO A 1 774 ? 35.033 68.641 -31.297 1.00 13.93 ? 774 PRO A CG 1 ATOM 6343 C CD . PRO A 1 774 ? 35.767 67.449 -31.756 1.00 10.48 ? 774 PRO A CD 1 ATOM 6344 N N . GLU A 1 775 ? 38.322 70.127 -28.844 1.00 8.29 ? 775 GLU A N 1 ATOM 6345 C CA A GLU A 1 775 ? 38.534 70.490 -27.454 0.50 8.48 ? 775 GLU A CA 1 ATOM 6346 C CA B GLU A 1 775 ? 38.529 70.497 -27.447 0.50 8.21 ? 775 GLU A CA 1 ATOM 6347 C C . GLU A 1 775 ? 37.560 71.617 -27.122 1.00 8.26 ? 775 GLU A C 1 ATOM 6348 O O . GLU A 1 775 ? 37.357 72.537 -27.942 1.00 8.85 ? 775 GLU A O 1 ATOM 6349 C CB A GLU A 1 775 ? 39.984 70.922 -27.237 0.50 8.99 ? 775 GLU A CB 1 ATOM 6350 C CB B GLU A 1 775 ? 39.966 70.956 -27.181 0.50 8.85 ? 775 GLU A CB 1 ATOM 6351 C CG A GLU A 1 775 ? 40.325 71.281 -25.789 0.50 9.53 ? 775 GLU A CG 1 ATOM 6352 C CG B GLU A 1 775 ? 40.168 71.553 -25.776 0.50 8.84 ? 775 GLU A CG 1 ATOM 6353 C CD A GLU A 1 775 ? 41.813 71.445 -25.533 0.50 11.80 ? 775 GLU A CD 1 ATOM 6354 C CD B GLU A 1 775 ? 41.605 71.954 -25.450 0.50 10.74 ? 775 GLU A CD 1 ATOM 6355 O OE1 A GLU A 1 775 ? 42.593 70.582 -25.971 0.50 14.01 ? 775 GLU A OE1 1 ATOM 6356 O OE1 B GLU A 1 775 ? 42.460 71.963 -26.364 0.50 12.43 ? 775 GLU A OE1 1 ATOM 6357 O OE2 A GLU A 1 775 ? 42.212 72.443 -24.894 0.50 13.75 ? 775 GLU A OE2 1 ATOM 6358 O OE2 B GLU A 1 775 ? 41.899 72.243 -24.261 0.50 11.43 ? 775 GLU A OE2 1 ATOM 6359 N N . ILE A 1 776 ? 36.921 71.550 -25.981 1.00 7.12 ? 776 ILE A N 1 ATOM 6360 C CA . ILE A 1 776 ? 36.071 72.614 -25.510 1.00 6.75 ? 776 ILE A CA 1 ATOM 6361 C C . ILE A 1 776 ? 36.723 73.232 -24.289 1.00 6.72 ? 776 ILE A C 1 ATOM 6362 O O . ILE A 1 776 ? 37.194 72.504 -23.414 1.00 6.97 ? 776 ILE A O 1 ATOM 6363 C CB . ILE A 1 776 ? 34.702 72.025 -25.108 1.00 8.04 ? 776 ILE A CB 1 ATOM 6364 C CG1 . ILE A 1 776 ? 34.114 71.106 -26.207 1.00 11.17 ? 776 ILE A CG1 1 ATOM 6365 C CG2 . ILE A 1 776 ? 33.757 73.133 -24.637 1.00 10.92 ? 776 ILE A CG2 1 ATOM 6366 C CD1 . ILE A 1 776 ? 33.943 71.753 -27.566 1.00 15.38 ? 776 ILE A CD1 1 ATOM 6367 N N . ARG A 1 777 ? 36.731 74.550 -24.201 1.00 7.15 ? 777 ARG A N 1 ATOM 6368 C CA . ARG A 1 777 ? 37.189 75.263 -23.009 1.00 6.67 ? 777 ARG A CA 1 ATOM 6369 C C . ARG A 1 777 ? 36.138 76.245 -22.609 1.00 7.57 ? 777 ARG A C 1 ATOM 6370 O O . ARG A 1 777 ? 35.654 77.012 -23.456 1.00 7.84 ? 777 ARG A O 1 ATOM 6371 C CB . ARG A 1 777 ? 38.492 76.001 -23.231 1.00 7.53 ? 777 ARG A CB 1 ATOM 6372 C CG . ARG A 1 777 ? 39.616 75.123 -23.651 1.00 9.07 ? 777 ARG A CG 1 ATOM 6373 C CD . ARG A 1 777 ? 40.935 75.869 -23.756 1.00 11.51 ? 777 ARG A CD 1 ATOM 6374 N NE . ARG A 1 777 ? 42.014 75.028 -24.288 1.00 12.85 ? 777 ARG A NE 1 ATOM 6375 C CZ . ARG A 1 777 ? 43.205 75.478 -24.683 1.00 18.29 ? 777 ARG A CZ 1 ATOM 6376 N NH1 . ARG A 1 777 ? 43.503 76.768 -24.546 1.00 20.74 ? 777 ARG A NH1 1 ATOM 6377 N NH2 . ARG A 1 777 ? 44.113 74.639 -25.183 1.00 19.62 ? 777 ARG A NH2 1 ATOM 6378 N N . ASN A 1 778 ? 35.755 76.245 -21.348 1.00 6.32 ? 778 ASN A N 1 ATOM 6379 C CA . ASN A 1 778 ? 34.828 77.217 -20.822 1.00 6.39 ? 778 ASN A CA 1 ATOM 6380 C C . ASN A 1 778 ? 35.540 77.987 -19.744 1.00 6.52 ? 778 ASN A C 1 ATOM 6381 O O . ASN A 1 778 ? 35.972 77.406 -18.745 1.00 6.20 ? 778 ASN A O 1 ATOM 6382 C CB . ASN A 1 778 ? 33.589 76.572 -20.160 1.00 6.85 ? 778 ASN A CB 1 ATOM 6383 C CG . ASN A 1 778 ? 32.701 75.883 -21.127 1.00 7.96 ? 778 ASN A CG 1 ATOM 6384 O OD1 . ASN A 1 778 ? 32.693 76.228 -22.319 1.00 8.90 ? 778 ASN A OD1 1 ATOM 6385 N ND2 . ASN A 1 778 ? 31.928 74.920 -20.631 1.00 8.87 ? 778 ASN A ND2 1 ATOM 6386 N N . LEU A 1 779 ? 35.633 79.297 -19.907 1.00 6.19 ? 779 LEU A N 1 ATOM 6387 C CA . LEU A 1 779 ? 36.075 80.168 -18.809 1.00 6.11 ? 779 LEU A CA 1 ATOM 6388 C C . LEU A 1 779 ? 34.838 80.628 -18.091 1.00 6.62 ? 779 LEU A C 1 ATOM 6389 O O . LEU A 1 779 ? 34.042 81.408 -18.622 1.00 7.13 ? 779 LEU A O 1 ATOM 6390 C CB . LEU A 1 779 ? 36.899 81.351 -19.342 1.00 7.52 ? 779 LEU A CB 1 ATOM 6391 C CG . LEU A 1 779 ? 37.428 82.289 -18.248 1.00 10.14 ? 779 LEU A CG 1 ATOM 6392 C CD1 . LEU A 1 779 ? 38.403 81.553 -17.398 1.00 11.97 ? 779 LEU A CD1 1 ATOM 6393 C CD2 . LEU A 1 779 ? 38.038 83.507 -18.950 1.00 15.06 ? 779 LEU A CD2 1 ATOM 6394 N N . VAL A 1 780 ? 34.617 80.023 -16.928 1.00 5.93 ? 780 VAL A N 1 ATOM 6395 C CA . VAL A 1 780 ? 33.353 80.198 -16.202 1.00 7.13 ? 780 VAL A CA 1 ATOM 6396 C C . VAL A 1 780 ? 33.526 81.189 -15.066 1.00 8.51 ? 780 VAL A C 1 ATOM 6397 O O . VAL A 1 780 ? 34.339 80.982 -14.166 1.00 9.26 ? 780 VAL A O 1 ATOM 6398 C CB . VAL A 1 780 ? 32.820 78.831 -15.647 1.00 7.04 ? 780 VAL A CB 1 ATOM 6399 C CG1 . VAL A 1 780 ? 31.474 78.991 -14.963 1.00 8.66 ? 780 VAL A CG1 1 ATOM 6400 C CG2 . VAL A 1 780 ? 32.749 77.798 -16.777 1.00 8.24 ? 780 VAL A CG2 1 ATOM 6401 N N . ASP A 1 781 ? 32.761 82.275 -15.155 1.00 8.41 ? 781 ASP A N 1 ATOM 6402 C CA . ASP A 1 781 ? 32.746 83.274 -14.106 1.00 8.75 ? 781 ASP A CA 1 ATOM 6403 C C . ASP A 1 781 ? 31.328 83.622 -13.750 1.00 9.75 ? 781 ASP A C 1 ATOM 6404 O O . ASP A 1 781 ? 30.686 84.481 -14.393 1.00 10.62 ? 781 ASP A O 1 ATOM 6405 C CB . ASP A 1 781 ? 33.489 84.510 -14.583 1.00 10.37 ? 781 ASP A CB 1 ATOM 6406 C CG . ASP A 1 781 ? 33.548 85.581 -13.522 1.00 14.23 ? 781 ASP A CG 1 ATOM 6407 O OD1 . ASP A 1 781 ? 33.094 85.368 -12.353 1.00 14.22 ? 781 ASP A OD1 1 ATOM 6408 O OD2 . ASP A 1 781 ? 34.092 86.685 -13.781 1.00 19.90 ? 781 ASP A OD2 1 ATOM 6409 N N . ILE A 1 782 ? 30.813 82.919 -12.751 1.00 9.62 ? 782 ILE A N 1 ATOM 6410 C CA . ILE A 1 782 ? 29.403 83.037 -12.325 1.00 11.98 ? 782 ILE A CA 1 ATOM 6411 C C . ILE A 1 782 ? 29.151 84.389 -11.659 1.00 13.59 ? 782 ILE A C 1 ATOM 6412 O O . ILE A 1 782 ? 27.990 84.798 -11.470 1.00 15.95 ? 782 ILE A O 1 ATOM 6413 C CB . ILE A 1 782 ? 29.046 81.843 -11.398 1.00 12.11 ? 782 ILE A CB 1 ATOM 6414 C CG1 . ILE A 1 782 ? 27.551 81.678 -11.216 1.00 13.90 ? 782 ILE A CG1 1 ATOM 6415 C CG2 . ILE A 1 782 ? 29.734 81.973 -10.053 1.00 14.20 ? 782 ILE A CG2 1 ATOM 6416 C CD1 . ILE A 1 782 ? 27.272 80.276 -10.769 1.00 14.59 ? 782 ILE A CD1 1 ATOM 6417 N N . GLY A 1 783 ? 30.225 85.115 -11.356 1.00 14.23 ? 783 GLY A N 1 ATOM 6418 C CA . GLY A 1 783 ? 30.108 86.504 -10.898 1.00 15.57 ? 783 GLY A CA 1 ATOM 6419 C C . GLY A 1 783 ? 29.252 86.613 -9.658 1.00 17.19 ? 783 GLY A C 1 ATOM 6420 O O . GLY A 1 783 ? 29.479 85.875 -8.695 1.00 18.66 ? 783 GLY A O 1 ATOM 6421 N N . SER A 1 784 ? 28.274 87.510 -9.681 1.00 19.61 ? 784 SER A N 1 ATOM 6422 C CA . SER A 1 784 ? 27.446 87.737 -8.497 1.00 20.50 ? 784 SER A CA 1 ATOM 6423 C C . SER A 1 784 ? 26.058 87.109 -8.648 1.00 20.61 ? 784 SER A C 1 ATOM 6424 O O . SER A 1 784 ? 25.113 87.523 -7.957 1.00 20.23 ? 784 SER A O 1 ATOM 6425 C CB . SER A 1 784 ? 27.352 89.236 -8.174 1.00 21.75 ? 784 SER A CB 1 ATOM 6426 O OG . SER A 1 784 ? 26.867 89.957 -9.298 1.00 25.84 ? 784 SER A OG 1 ATOM 6427 N N . LEU A 1 785 ? 25.926 86.122 -9.543 1.00 19.29 ? 785 LEU A N 1 ATOM 6428 C CA . LEU A 1 785 ? 24.626 85.478 -9.763 1.00 19.63 ? 785 LEU A CA 1 ATOM 6429 C C . LEU A 1 785 ? 24.245 84.535 -8.638 1.00 19.81 ? 785 LEU A C 1 ATOM 6430 O O . LEU A 1 785 ? 24.535 83.322 -8.699 1.00 20.86 ? 785 LEU A O 1 ATOM 6431 C CB . LEU A 1 785 ? 24.614 84.693 -11.071 1.00 19.65 ? 785 LEU A CB 1 ATOM 6432 C CG . LEU A 1 785 ? 24.816 85.480 -12.366 1.00 20.45 ? 785 LEU A CG 1 ATOM 6433 C CD1 . LEU A 1 785 ? 24.779 84.514 -13.531 1.00 23.01 ? 785 LEU A CD1 1 ATOM 6434 C CD2 . LEU A 1 785 ? 23.766 86.570 -12.513 1.00 22.92 ? 785 LEU A CD2 1 ATOM 6435 N N . ASP A 1 786 ? 23.530 85.045 -7.639 1.00 19.00 ? 786 ASP A N 1 ATOM 6436 C CA . ASP A 1 786 ? 23.241 84.223 -6.476 1.00 17.97 ? 786 ASP A CA 1 ATOM 6437 C C . ASP A 1 786 ? 22.216 83.121 -6.798 1.00 15.57 ? 786 ASP A C 1 ATOM 6438 O O . ASP A 1 786 ? 21.352 83.254 -7.689 1.00 14.20 ? 786 ASP A O 1 ATOM 6439 C CB . ASP A 1 786 ? 22.763 85.060 -5.270 1.00 20.02 ? 786 ASP A CB 1 ATOM 6440 C CG . ASP A 1 786 ? 23.910 85.633 -4.421 1.00 22.91 ? 786 ASP A CG 1 ATOM 6441 O OD1 . ASP A 1 786 ? 25.011 85.975 -4.942 1.00 24.55 ? 786 ASP A OD1 1 ATOM 6442 O OD2 . ASP A 1 786 ? 23.771 85.777 -3.180 1.00 26.02 ? 786 ASP A OD2 1 ATOM 6443 N N . ASN A 1 787 ? 22.341 82.030 -6.056 1.00 13.01 ? 787 ASN A N 1 ATOM 6444 C CA . ASN A 1 787 ? 21.410 80.913 -6.135 1.00 11.88 ? 787 ASN A CA 1 ATOM 6445 C C . ASN A 1 787 ? 21.217 80.404 -7.549 1.00 11.13 ? 787 ASN A C 1 ATOM 6446 O O . ASN A 1 787 ? 20.101 80.248 -8.038 1.00 11.70 ? 787 ASN A O 1 ATOM 6447 C CB . ASN A 1 787 ? 20.094 81.283 -5.439 1.00 11.75 ? 787 ASN A CB 1 ATOM 6448 C CG . ASN A 1 787 ? 20.303 81.509 -3.982 1.00 15.08 ? 787 ASN A CG 1 ATOM 6449 O OD1 . ASN A 1 787 ? 21.043 80.748 -3.334 1.00 16.14 ? 787 ASN A OD1 1 ATOM 6450 N ND2 . ASN A 1 787 ? 19.671 82.563 -3.434 1.00 20.85 ? 787 ASN A ND2 1 ATOM 6451 N N . THR A 1 788 ? 22.343 80.161 -8.207 1.00 10.57 ? 788 THR A N 1 ATOM 6452 C CA . THR A 1 788 ? 22.375 79.765 -9.595 1.00 10.44 ? 788 THR A CA 1 ATOM 6453 C C . THR A 1 788 ? 23.396 78.652 -9.790 1.00 8.80 ? 788 THR A C 1 ATOM 6454 O O . THR A 1 788 ? 24.515 78.742 -9.262 1.00 9.45 ? 788 THR A O 1 ATOM 6455 C CB . THR A 1 788 ? 22.792 80.981 -10.441 1.00 11.62 ? 788 THR A CB 1 ATOM 6456 O OG1 . THR A 1 788 ? 21.747 81.973 -10.369 1.00 14.81 ? 788 THR A OG1 1 ATOM 6457 C CG2 . THR A 1 788 ? 22.853 80.621 -11.898 1.00 13.18 ? 788 THR A CG2 1 ATOM 6458 N N . GLU A 1 789 ? 23.013 77.657 -10.583 1.00 7.47 ? 789 GLU A N 1 ATOM 6459 C CA . GLU A 1 789 ? 23.975 76.642 -11.016 1.00 7.89 ? 789 GLU A CA 1 ATOM 6460 C C . GLU A 1 789 ? 23.972 76.648 -12.530 1.00 7.15 ? 789 GLU A C 1 ATOM 6461 O O . GLU A 1 789 ? 22.891 76.550 -13.131 1.00 9.61 ? 789 GLU A O 1 ATOM 6462 C CB . GLU A 1 789 ? 23.653 75.253 -10.430 1.00 8.08 ? 789 GLU A CB 1 ATOM 6463 C CG . GLU A 1 789 ? 23.234 75.270 -8.958 1.00 8.80 ? 789 GLU A CG 1 ATOM 6464 C CD . GLU A 1 789 ? 23.422 73.947 -8.245 1.00 8.72 ? 789 GLU A CD 1 ATOM 6465 O OE1 . GLU A 1 789 ? 24.261 73.128 -8.724 1.00 9.42 ? 789 GLU A OE1 1 ATOM 6466 O OE2 . GLU A 1 789 ? 22.798 73.785 -7.196 1.00 8.64 ? 789 GLU A OE2 1 ATOM 6467 N N . ILE A 1 790 ? 25.124 76.794 -13.150 1.00 6.87 ? 790 ILE A N 1 ATOM 6468 C CA A ILE A 1 790 ? 25.209 76.842 -14.613 0.50 8.12 ? 790 ILE A CA 1 ATOM 6469 C CA B ILE A 1 790 ? 25.227 76.854 -14.613 0.50 7.79 ? 790 ILE A CA 1 ATOM 6470 C C . ILE A 1 790 ? 25.568 75.469 -15.128 1.00 7.74 ? 790 ILE A C 1 ATOM 6471 O O . ILE A 1 790 ? 26.547 74.865 -14.661 1.00 7.28 ? 790 ILE A O 1 ATOM 6472 C CB A ILE A 1 790 ? 26.262 77.866 -15.101 0.50 8.64 ? 790 ILE A CB 1 ATOM 6473 C CB B ILE A 1 790 ? 26.303 77.909 -15.067 0.50 8.75 ? 790 ILE A CB 1 ATOM 6474 C CG1 A ILE A 1 790 ? 26.013 79.247 -14.469 0.50 10.58 ? 790 ILE A CG1 1 ATOM 6475 C CG1 B ILE A 1 790 ? 25.839 79.356 -14.769 0.50 10.31 ? 790 ILE A CG1 1 ATOM 6476 C CG2 A ILE A 1 790 ? 26.275 77.951 -16.637 0.50 9.40 ? 790 ILE A CG2 1 ATOM 6477 C CG2 B ILE A 1 790 ? 26.715 77.751 -16.547 0.50 8.87 ? 790 ILE A CG2 1 ATOM 6478 C CD1 A ILE A 1 790 ? 27.066 80.280 -14.812 0.50 9.73 ? 790 ILE A CD1 1 ATOM 6479 C CD1 B ILE A 1 790 ? 24.441 79.718 -15.231 0.50 13.54 ? 790 ILE A CD1 1 ATOM 6480 N N . VAL A 1 791 ? 24.772 74.975 -16.058 1.00 6.74 ? 791 VAL A N 1 ATOM 6481 C CA . VAL A 1 791 ? 24.992 73.671 -16.673 1.00 7.28 ? 791 VAL A CA 1 ATOM 6482 C C . VAL A 1 791 ? 25.265 73.798 -18.151 1.00 6.88 ? 791 VAL A C 1 ATOM 6483 O O . VAL A 1 791 ? 24.688 74.681 -18.831 1.00 6.64 ? 791 VAL A O 1 ATOM 6484 C CB . VAL A 1 791 ? 23.815 72.732 -16.393 1.00 7.02 ? 791 VAL A CB 1 ATOM 6485 C CG1 . VAL A 1 791 ? 22.579 73.128 -17.165 1.00 10.19 ? 791 VAL A CG1 1 ATOM 6486 C CG2 . VAL A 1 791 ? 24.159 71.316 -16.734 1.00 9.89 ? 791 VAL A CG2 1 ATOM 6487 N N . MET A 1 792 ? 26.157 72.976 -18.653 1.00 6.01 ? 792 MET A N 1 ATOM 6488 C CA . MET A 1 792 ? 26.396 72.844 -20.089 1.00 5.80 ? 792 MET A CA 1 ATOM 6489 C C . MET A 1 792 ? 25.756 71.543 -20.564 1.00 6.94 ? 792 MET A C 1 ATOM 6490 O O . MET A 1 792 ? 26.093 70.459 -20.043 1.00 6.86 ? 792 MET A O 1 ATOM 6491 C CB . MET A 1 792 ? 27.897 72.849 -20.422 1.00 6.37 ? 792 MET A CB 1 ATOM 6492 C CG . MET A 1 792 ? 28.192 72.748 -21.899 1.00 8.42 ? 792 MET A CG 1 ATOM 6493 S SD . MET A 1 792 ? 29.972 72.748 -22.260 1.00 10.20 ? 792 MET A SD 1 ATOM 6494 C CE . MET A 1 792 ? 30.504 71.279 -21.441 1.00 11.74 ? 792 MET A CE 1 ATOM 6495 N N . ARG A 1 793 ? 24.833 71.633 -21.520 1.00 7.10 ? 793 ARG A N 1 ATOM 6496 C CA . ARG A 1 793 ? 24.120 70.466 -22.030 1.00 7.51 ? 793 ARG A CA 1 ATOM 6497 C C . ARG A 1 793 ? 24.461 70.248 -23.485 1.00 8.10 ? 793 ARG A C 1 ATOM 6498 O O . ARG A 1 793 ? 24.637 71.214 -24.254 1.00 8.03 ? 793 ARG A O 1 ATOM 6499 C CB . ARG A 1 793 ? 22.625 70.671 -21.836 1.00 8.15 ? 793 ARG A CB 1 ATOM 6500 C CG . ARG A 1 793 ? 21.790 69.491 -22.320 1.00 7.15 ? 793 ARG A CG 1 ATOM 6501 C CD . ARG A 1 793 ? 20.298 69.652 -21.997 1.00 9.63 ? 793 ARG A CD 1 ATOM 6502 N NE . ARG A 1 793 ? 20.066 69.782 -20.556 1.00 9.44 ? 793 ARG A NE 1 ATOM 6503 C CZ . ARG A 1 793 ? 18.970 70.296 -19.998 1.00 11.30 ? 793 ARG A CZ 1 ATOM 6504 N NH1 . ARG A 1 793 ? 17.984 70.752 -20.789 1.00 11.29 ? 793 ARG A NH1 1 ATOM 6505 N NH2 . ARG A 1 793 ? 18.873 70.408 -18.684 1.00 10.41 ? 793 ARG A NH2 1 ATOM 6506 N N . LEU A 1 794 ? 24.515 68.981 -23.878 1.00 7.72 ? 794 LEU A N 1 ATOM 6507 C CA . LEU A 1 794 ? 24.646 68.541 -25.264 1.00 7.96 ? 794 LEU A CA 1 ATOM 6508 C C . LEU A 1 794 ? 23.353 67.834 -25.636 1.00 8.74 ? 794 LEU A C 1 ATOM 6509 O O . LEU A 1 794 ? 22.916 66.944 -24.922 1.00 8.66 ? 794 LEU A O 1 ATOM 6510 C CB . LEU A 1 794 ? 25.786 67.537 -25.433 1.00 9.81 ? 794 LEU A CB 1 ATOM 6511 C CG . LEU A 1 794 ? 27.127 68.231 -25.541 1.00 10.96 ? 794 LEU A CG 1 ATOM 6512 C CD1 . LEU A 1 794 ? 28.232 67.227 -25.248 1.00 14.45 ? 794 LEU A CD1 1 ATOM 6513 C CD2 . LEU A 1 794 ? 27.289 68.742 -26.966 1.00 16.82 ? 794 LEU A CD2 1 ATOM 6514 N N . GLU A 1 795 ? 22.753 68.241 -26.744 1.00 8.85 ? 795 GLU A N 1 ATOM 6515 C CA . GLU A 1 795 ? 21.512 67.618 -27.247 1.00 10.65 ? 795 GLU A CA 1 ATOM 6516 C C . GLU A 1 795 ? 21.827 66.912 -28.553 1.00 10.04 ? 795 GLU A C 1 ATOM 6517 O O . GLU A 1 795 ? 22.407 67.504 -29.459 1.00 10.21 ? 795 GLU A O 1 ATOM 6518 C CB . GLU A 1 795 ? 20.438 68.681 -27.493 1.00 11.52 ? 795 GLU A CB 1 ATOM 6519 C CG . GLU A 1 795 ? 20.082 69.443 -26.232 1.00 14.78 ? 795 GLU A CG 1 ATOM 6520 C CD . GLU A 1 795 ? 19.200 70.681 -26.438 1.00 15.99 ? 795 GLU A CD 1 ATOM 6521 O OE1 . GLU A 1 795 ? 19.193 71.268 -27.541 1.00 24.83 ? 795 GLU A OE1 1 ATOM 6522 O OE2 . GLU A 1 795 ? 18.532 71.099 -25.466 1.00 22.84 ? 795 GLU A OE2 1 ATOM 6523 N N . THR A 1 796 ? 21.462 65.636 -28.651 1.00 9.74 ? 796 THR A N 1 ATOM 6524 C CA . THR A 1 796 ? 21.731 64.862 -29.837 1.00 9.66 ? 796 THR A CA 1 ATOM 6525 C C . THR A 1 796 ? 20.484 64.046 -30.186 1.00 9.79 ? 796 THR A C 1 ATOM 6526 O O . THR A 1 796 ? 19.513 64.056 -29.426 1.00 11.72 ? 796 THR A O 1 ATOM 6527 C CB . THR A 1 796 ? 22.900 63.859 -29.655 1.00 10.61 ? 796 THR A CB 1 ATOM 6528 O OG1 . THR A 1 796 ? 22.466 62.709 -28.901 1.00 10.09 ? 796 THR A OG1 1 ATOM 6529 C CG2 . THR A 1 796 ? 24.076 64.441 -28.886 1.00 11.65 ? 796 THR A CG2 1 ATOM 6530 N N A HIS A 1 797 ? 20.607 63.330 -31.304 0.50 9.29 ? 797 HIS A N 1 ATOM 6531 N N B HIS A 1 797 ? 20.525 63.328 -31.310 0.50 10.16 ? 797 HIS A N 1 ATOM 6532 C CA A HIS A 1 797 ? 19.576 62.410 -31.771 0.50 10.26 ? 797 HIS A CA 1 ATOM 6533 C CA B HIS A 1 797 ? 19.447 62.369 -31.649 0.50 11.31 ? 797 HIS A CA 1 ATOM 6534 C C A HIS A 1 797 ? 19.731 61.029 -31.205 0.50 10.40 ? 797 HIS A C 1 ATOM 6535 C C B HIS A 1 797 ? 19.956 60.918 -31.483 0.50 10.98 ? 797 HIS A C 1 ATOM 6536 O O A HIS A 1 797 ? 18.801 60.231 -31.375 0.50 9.59 ? 797 HIS A O 1 ATOM 6537 O O B HIS A 1 797 ? 19.510 59.949 -32.133 0.50 8.76 ? 797 HIS A O 1 ATOM 6538 C CB A HIS A 1 797 ? 19.502 62.370 -33.312 0.50 9.34 ? 797 HIS A CB 1 ATOM 6539 C CB B HIS A 1 797 ? 18.858 62.635 -33.049 0.50 11.76 ? 797 HIS A CB 1 ATOM 6540 C CG A HIS A 1 797 ? 18.776 63.543 -33.885 0.50 8.68 ? 797 HIS A CG 1 ATOM 6541 C CG B HIS A 1 797 ? 18.346 64.032 -33.261 0.50 14.24 ? 797 HIS A CG 1 ATOM 6542 N ND1 A HIS A 1 797 ? 18.059 64.422 -33.094 0.50 10.58 ? 797 HIS A ND1 1 ATOM 6543 N ND1 B HIS A 1 797 ? 18.023 64.894 -32.232 0.50 14.72 ? 797 HIS A ND1 1 ATOM 6544 C CD2 A HIS A 1 797 ? 18.679 64.006 -35.150 0.50 11.06 ? 797 HIS A CD2 1 ATOM 6545 C CD2 B HIS A 1 797 ? 18.068 64.702 -34.407 0.50 13.49 ? 797 HIS A CD2 1 ATOM 6546 C CE1 A HIS A 1 797 ? 17.539 65.365 -33.857 0.50 6.79 ? 797 HIS A CE1 1 ATOM 6547 C CE1 B HIS A 1 797 ? 17.592 66.038 -32.736 0.50 15.90 ? 797 HIS A CE1 1 ATOM 6548 N NE2 A HIS A 1 797 ? 17.905 65.141 -35.104 0.50 11.26 ? 797 HIS A NE2 1 ATOM 6549 N NE2 B HIS A 1 797 ? 17.615 65.948 -34.052 0.50 15.04 ? 797 HIS A NE2 1 ATOM 6550 N N . ILE A 1 798 ? 20.883 60.742 -30.550 1.00 9.79 ? 798 ILE A N 1 ATOM 6551 C CA . ILE A 1 798 ? 21.281 59.390 -30.166 1.00 9.63 ? 798 ILE A CA 1 ATOM 6552 C C . ILE A 1 798 ? 20.182 58.761 -29.329 1.00 9.45 ? 798 ILE A C 1 ATOM 6553 O O . ILE A 1 798 ? 19.657 59.366 -28.436 1.00 10.15 ? 798 ILE A O 1 ATOM 6554 C CB . ILE A 1 798 ? 22.597 59.452 -29.392 1.00 8.53 ? 798 ILE A CB 1 ATOM 6555 C CG1 . ILE A 1 798 ? 23.718 59.884 -30.312 1.00 9.99 ? 798 ILE A CG1 1 ATOM 6556 C CG2 . ILE A 1 798 ? 22.889 58.076 -28.778 1.00 10.03 ? 798 ILE A CG2 1 ATOM 6557 C CD1 . ILE A 1 798 ? 25.052 60.194 -29.579 1.00 10.80 ? 798 ILE A CD1 1 ATOM 6558 N N . ASP A 1 799 ? 19.813 57.533 -29.683 1.00 11.33 ? 799 ASP A N 1 ATOM 6559 C CA . ASP A 1 799 ? 18.670 56.921 -29.053 1.00 10.66 ? 799 ASP A CA 1 ATOM 6560 C C . ASP A 1 799 ? 19.111 56.145 -27.804 1.00 11.07 ? 799 ASP A C 1 ATOM 6561 O O . ASP A 1 799 ? 19.062 54.921 -27.740 1.00 9.88 ? 799 ASP A O 1 ATOM 6562 C CB . ASP A 1 799 ? 17.976 55.976 -30.061 1.00 13.20 ? 799 ASP A CB 1 ATOM 6563 C CG . ASP A 1 799 ? 16.640 55.456 -29.570 1.00 15.53 ? 799 ASP A CG 1 ATOM 6564 O OD1 . ASP A 1 799 ? 16.010 56.053 -28.681 1.00 20.51 ? 799 ASP A OD1 1 ATOM 6565 O OD2 . ASP A 1 799 ? 16.163 54.392 -30.017 1.00 20.93 ? 799 ASP A OD2 1 ATOM 6566 N N . SER A 1 800 ? 19.540 56.896 -26.790 1.00 10.43 ? 800 SER A N 1 ATOM 6567 C CA . SER A 1 800 ? 20.098 56.296 -25.584 1.00 9.74 ? 800 SER A CA 1 ATOM 6568 C C . SER A 1 800 ? 19.052 55.897 -24.574 1.00 9.29 ? 800 SER A C 1 ATOM 6569 O O . SER A 1 800 ? 19.326 55.102 -23.655 1.00 9.09 ? 800 SER A O 1 ATOM 6570 C CB . SER A 1 800 ? 21.074 57.285 -24.930 1.00 9.33 ? 800 SER A CB 1 ATOM 6571 O OG . SER A 1 800 ? 20.446 58.514 -24.647 1.00 7.92 ? 800 SER A OG 1 ATOM 6572 N N . GLY A 1 801 ? 17.838 56.424 -24.691 1.00 9.49 ? 801 GLY A N 1 ATOM 6573 C CA . GLY A 1 801 ? 16.798 56.022 -23.780 1.00 9.39 ? 801 GLY A CA 1 ATOM 6574 C C . GLY A 1 801 ? 17.072 56.565 -22.409 1.00 9.28 ? 801 GLY A C 1 ATOM 6575 O O . GLY A 1 801 ? 17.132 57.776 -22.234 1.00 10.36 ? 801 GLY A O 1 ATOM 6576 N N . ASP A 1 802 ? 17.197 55.658 -21.448 1.00 8.98 ? 802 ASP A N 1 ATOM 6577 C CA . ASP A 1 802 ? 17.472 56.066 -20.087 1.00 9.40 ? 802 ASP A CA 1 ATOM 6578 C C . ASP A 1 802 ? 18.866 55.659 -19.637 1.00 9.58 ? 802 ASP A C 1 ATOM 6579 O O . ASP A 1 802 ? 19.152 55.753 -18.454 1.00 8.97 ? 802 ASP A O 1 ATOM 6580 C CB . ASP A 1 802 ? 16.417 55.509 -19.114 1.00 11.26 ? 802 ASP A CB 1 ATOM 6581 C CG . ASP A 1 802 ? 16.248 54.012 -19.202 1.00 13.72 ? 802 ASP A CG 1 ATOM 6582 O OD1 . ASP A 1 802 ? 17.025 53.303 -19.894 1.00 17.64 ? 802 ASP A OD1 1 ATOM 6583 O OD2 . ASP A 1 802 ? 15.327 53.439 -18.541 1.00 17.93 ? 802 ASP A OD2 1 ATOM 6584 N N . ILE A 1 803 ? 19.695 55.211 -20.558 1.00 7.44 ? 803 ILE A N 1 ATOM 6585 C CA . ILE A 1 803 ? 21.033 54.713 -20.207 1.00 7.24 ? 803 ILE A CA 1 ATOM 6586 C C . ILE A 1 803 ? 22.101 55.749 -20.501 1.00 7.11 ? 803 ILE A C 1 ATOM 6587 O O . ILE A 1 803 ? 22.058 56.436 -21.525 1.00 6.82 ? 803 ILE A O 1 ATOM 6588 C CB . ILE A 1 803 ? 21.347 53.415 -21.001 1.00 7.59 ? 803 ILE A CB 1 ATOM 6589 C CG1 . ILE A 1 803 ? 20.309 52.332 -20.675 1.00 10.50 ? 803 ILE A CG1 1 ATOM 6590 C CG2 . ILE A 1 803 ? 22.778 52.929 -20.775 1.00 7.77 ? 803 ILE A CG2 1 ATOM 6591 C CD1 . ILE A 1 803 ? 20.247 52.013 -19.198 1.00 11.38 ? 803 ILE A CD1 1 ATOM 6592 N N . PHE A 1 804 ? 23.102 55.820 -19.622 1.00 5.56 ? 804 PHE A N 1 ATOM 6593 C CA . PHE A 1 804 ? 24.283 56.634 -19.854 1.00 5.78 ? 804 PHE A CA 1 ATOM 6594 C C . PHE A 1 804 ? 25.418 56.035 -19.052 1.00 4.82 ? 804 PHE A C 1 ATOM 6595 O O . PHE A 1 804 ? 25.179 55.154 -18.214 1.00 7.91 ? 804 PHE A O 1 ATOM 6596 C CB . PHE A 1 804 ? 24.065 58.144 -19.553 1.00 4.87 ? 804 PHE A CB 1 ATOM 6597 C CG . PHE A 1 804 ? 23.650 58.481 -18.143 1.00 6.05 ? 804 PHE A CG 1 ATOM 6598 C CD1 . PHE A 1 804 ? 22.366 58.287 -17.694 1.00 4.70 ? 804 PHE A CD1 1 ATOM 6599 C CD2 . PHE A 1 804 ? 24.570 59.095 -17.278 1.00 6.90 ? 804 PHE A CD2 1 ATOM 6600 C CE1 . PHE A 1 804 ? 21.970 58.644 -16.424 1.00 7.09 ? 804 PHE A CE1 1 ATOM 6601 C CE2 . PHE A 1 804 ? 24.194 59.473 -16.030 1.00 5.27 ? 804 PHE A CE2 1 ATOM 6602 C CZ . PHE A 1 804 ? 22.905 59.252 -15.575 1.00 6.81 ? 804 PHE A CZ 1 ATOM 6603 N N . TYR A 1 805 ? 26.626 56.484 -19.306 1.00 4.52 ? 805 TYR A N 1 ATOM 6604 C CA . TYR A 1 805 ? 27.790 55.929 -18.624 1.00 4.40 ? 805 TYR A CA 1 ATOM 6605 C C . TYR A 1 805 ? 28.609 57.034 -18.042 1.00 5.48 ? 805 TYR A C 1 ATOM 6606 O O . TYR A 1 805 ? 28.780 58.051 -18.697 1.00 5.50 ? 805 TYR A O 1 ATOM 6607 C CB . TYR A 1 805 ? 28.651 55.162 -19.610 1.00 5.73 ? 805 TYR A CB 1 ATOM 6608 C CG . TYR A 1 805 ? 27.976 53.929 -20.192 1.00 5.10 ? 805 TYR A CG 1 ATOM 6609 C CD1 . TYR A 1 805 ? 26.989 54.027 -21.189 1.00 7.66 ? 805 TYR A CD1 1 ATOM 6610 C CD2 . TYR A 1 805 ? 28.271 52.676 -19.666 1.00 6.29 ? 805 TYR A CD2 1 ATOM 6611 C CE1 . TYR A 1 805 ? 26.376 52.875 -21.662 1.00 6.62 ? 805 TYR A CE1 1 ATOM 6612 C CE2 . TYR A 1 805 ? 27.663 51.500 -20.187 1.00 6.62 ? 805 TYR A CE2 1 ATOM 6613 C CZ . TYR A 1 805 ? 26.692 51.643 -21.150 1.00 6.81 ? 805 TYR A CZ 1 ATOM 6614 O OH . TYR A 1 805 ? 26.043 50.538 -21.704 1.00 8.26 ? 805 TYR A OH 1 ATOM 6615 N N . THR A 1 806 ? 29.126 56.816 -16.833 1.00 5.16 ? 806 THR A N 1 ATOM 6616 C CA . THR A 1 806 ? 29.967 57.836 -16.180 1.00 4.97 ? 806 THR A CA 1 ATOM 6617 C C . THR A 1 806 ? 31.141 57.100 -15.617 1.00 5.91 ? 806 THR A C 1 ATOM 6618 O O . THR A 1 806 ? 31.090 55.902 -15.331 1.00 6.32 ? 806 THR A O 1 ATOM 6619 C CB . THR A 1 806 ? 29.240 58.620 -15.106 1.00 5.98 ? 806 THR A CB 1 ATOM 6620 O OG1 . THR A 1 806 ? 28.852 57.723 -14.070 1.00 5.72 ? 806 THR A OG1 1 ATOM 6621 C CG2 . THR A 1 806 ? 27.964 59.288 -15.634 1.00 6.01 ? 806 THR A CG2 1 ATOM 6622 N N . ASP A 1 807 ? 32.240 57.788 -15.427 1.00 5.55 ? 807 ASP A N 1 ATOM 6623 C CA . ASP A 1 807 ? 33.380 57.105 -14.856 1.00 6.92 ? 807 ASP A CA 1 ATOM 6624 C C . ASP A 1 807 ? 33.432 57.148 -13.342 1.00 5.20 ? 807 ASP A C 1 ATOM 6625 O O . ASP A 1 807 ? 32.794 57.954 -12.728 1.00 6.30 ? 807 ASP A O 1 ATOM 6626 C CB . ASP A 1 807 ? 34.670 57.566 -15.483 1.00 9.29 ? 807 ASP A CB 1 ATOM 6627 C CG . ASP A 1 807 ? 35.124 58.836 -14.948 1.00 11.73 ? 807 ASP A CG 1 ATOM 6628 O OD1 . ASP A 1 807 ? 34.362 59.804 -14.968 1.00 12.98 ? 807 ASP A OD1 1 ATOM 6629 O OD2 . ASP A 1 807 ? 36.269 58.880 -14.468 1.00 14.71 ? 807 ASP A OD2 1 ATOM 6630 N N . LEU A 1 808 ? 34.197 56.221 -12.791 1.00 5.41 ? 808 LEU A N 1 ATOM 6631 C CA . LEU A 1 808 ? 34.461 56.170 -11.362 1.00 5.02 ? 808 LEU A CA 1 ATOM 6632 C C . LEU A 1 808 ? 35.951 56.388 -11.189 1.00 4.14 ? 808 LEU A C 1 ATOM 6633 O O . LEU A 1 808 ? 36.746 55.553 -11.603 1.00 5.26 ? 808 LEU A O 1 ATOM 6634 C CB . LEU A 1 808 ? 34.077 54.825 -10.759 1.00 6.13 ? 808 LEU A CB 1 ATOM 6635 C CG . LEU A 1 808 ? 32.545 54.692 -10.622 1.00 5.96 ? 808 LEU A CG 1 ATOM 6636 C CD1 . LEU A 1 808 ? 32.255 53.221 -10.361 1.00 7.78 ? 808 LEU A CD1 1 ATOM 6637 C CD2 . LEU A 1 808 ? 32.009 55.553 -9.495 1.00 9.40 ? 808 LEU A CD2 1 ATOM 6638 N N . ASN A 1 809 ? 36.306 57.539 -10.632 1.00 4.36 ? 809 ASN A N 1 ATOM 6639 C CA . ASN A 1 809 ? 37.697 57.847 -10.273 1.00 4.46 ? 809 ASN A CA 1 ATOM 6640 C C . ASN A 1 809 ? 38.649 57.750 -11.434 1.00 4.71 ? 809 ASN A C 1 ATOM 6641 O O . ASN A 1 809 ? 39.837 57.505 -11.237 1.00 4.84 ? 809 ASN A O 1 ATOM 6642 C CB . ASN A 1 809 ? 38.175 56.957 -9.120 1.00 4.51 ? 809 ASN A CB 1 ATOM 6643 C CG . ASN A 1 809 ? 37.146 56.879 -8.049 1.00 4.81 ? 809 ASN A CG 1 ATOM 6644 O OD1 . ASN A 1 809 ? 36.317 55.968 -8.023 1.00 5.68 ? 809 ASN A OD1 1 ATOM 6645 N ND2 . ASN A 1 809 ? 37.162 57.851 -7.145 1.00 5.53 ? 809 ASN A ND2 1 ATOM 6646 N N . GLY A 1 810 ? 38.168 57.937 -12.667 1.00 5.30 ? 810 GLY A N 1 ATOM 6647 C CA . GLY A 1 810 ? 39.128 57.878 -13.771 1.00 6.12 ? 810 GLY A CA 1 ATOM 6648 C C . GLY A 1 810 ? 39.611 56.490 -14.093 1.00 6.96 ? 810 GLY A C 1 ATOM 6649 O O . GLY A 1 810 ? 40.555 56.329 -14.883 1.00 9.21 ? 810 GLY A O 1 ATOM 6650 N N . LEU A 1 811 ? 38.980 55.478 -13.485 1.00 6.36 ? 811 LEU A N 1 ATOM 6651 C CA . LEU A 1 811 ? 39.431 54.107 -13.577 1.00 7.64 ? 811 LEU A CA 1 ATOM 6652 C C . LEU A 1 811 ? 38.538 53.199 -14.450 1.00 7.58 ? 811 LEU A C 1 ATOM 6653 O O . LEU A 1 811 ? 39.047 52.298 -15.139 1.00 9.53 ? 811 LEU A O 1 ATOM 6654 C CB . LEU A 1 811 ? 39.518 53.534 -12.147 1.00 8.09 ? 811 LEU A CB 1 ATOM 6655 C CG . LEU A 1 811 ? 39.995 52.096 -12.000 1.00 9.83 ? 811 LEU A CG 1 ATOM 6656 C CD1 . LEU A 1 811 ? 41.419 51.929 -12.524 1.00 10.79 ? 811 LEU A CD1 1 ATOM 6657 C CD2 . LEU A 1 811 ? 39.877 51.603 -10.538 1.00 10.62 ? 811 LEU A CD2 1 ATOM 6658 N N . GLN A 1 812 ? 37.232 53.402 -14.358 1.00 5.94 ? 812 GLN A N 1 ATOM 6659 C CA . GLN A 1 812 ? 36.270 52.481 -14.996 1.00 6.57 ? 812 GLN A CA 1 ATOM 6660 C C . GLN A 1 812 ? 35.035 53.270 -15.341 1.00 6.60 ? 812 GLN A C 1 ATOM 6661 O O . GLN A 1 812 ? 34.764 54.328 -14.749 1.00 6.99 ? 812 GLN A O 1 ATOM 6662 C CB . GLN A 1 812 ? 35.947 51.339 -14.040 1.00 7.66 ? 812 GLN A CB 1 ATOM 6663 C CG . GLN A 1 812 ? 35.391 51.844 -12.709 1.00 9.37 ? 812 GLN A CG 1 ATOM 6664 C CD . GLN A 1 812 ? 35.132 50.706 -11.745 1.00 11.97 ? 812 GLN A CD 1 ATOM 6665 O OE1 . GLN A 1 812 ? 34.180 49.979 -11.904 1.00 11.15 ? 812 GLN A OE1 1 ATOM 6666 N NE2 . GLN A 1 812 ? 35.967 50.590 -10.727 1.00 13.42 ? 812 GLN A NE2 1 ATOM 6667 N N . PHE A 1 813 ? 34.284 52.803 -16.316 1.00 6.56 ? 813 PHE A N 1 ATOM 6668 C CA . PHE A 1 813 ? 33.017 53.432 -16.674 1.00 5.79 ? 813 PHE A CA 1 ATOM 6669 C C . PHE A 1 813 ? 31.901 52.528 -16.246 1.00 6.22 ? 813 PHE A C 1 ATOM 6670 O O . PHE A 1 813 ? 31.908 51.301 -16.536 1.00 8.28 ? 813 PHE A O 1 ATOM 6671 C CB . PHE A 1 813 ? 32.926 53.737 -18.171 1.00 5.58 ? 813 PHE A CB 1 ATOM 6672 C CG . PHE A 1 813 ? 33.665 54.967 -18.543 1.00 6.34 ? 813 PHE A CG 1 ATOM 6673 C CD1 . PHE A 1 813 ? 35.036 54.968 -18.661 1.00 7.00 ? 813 PHE A CD1 1 ATOM 6674 C CD2 . PHE A 1 813 ? 32.965 56.159 -18.742 1.00 7.16 ? 813 PHE A CD2 1 ATOM 6675 C CE1 . PHE A 1 813 ? 35.725 56.174 -18.929 1.00 9.10 ? 813 PHE A CE1 1 ATOM 6676 C CE2 . PHE A 1 813 ? 33.649 57.329 -19.038 1.00 8.63 ? 813 PHE A CE2 1 ATOM 6677 C CZ . PHE A 1 813 ? 35.005 57.323 -19.131 1.00 7.89 ? 813 PHE A CZ 1 ATOM 6678 N N . ILE A 1 814 ? 30.929 53.087 -15.565 1.00 4.90 ? 814 ILE A N 1 ATOM 6679 C CA . ILE A 1 814 ? 29.826 52.302 -15.044 1.00 5.12 ? 814 ILE A CA 1 ATOM 6680 C C . ILE A 1 814 ? 28.526 52.722 -15.711 1.00 5.87 ? 814 ILE A C 1 ATOM 6681 O O . ILE A 1 814 ? 28.299 53.929 -15.984 1.00 5.54 ? 814 ILE A O 1 ATOM 6682 C CB . ILE A 1 814 ? 29.762 52.446 -13.492 1.00 6.33 ? 814 ILE A CB 1 ATOM 6683 C CG1 . ILE A 1 814 ? 28.719 51.502 -12.883 1.00 6.89 ? 814 ILE A CG1 1 ATOM 6684 C CG2 . ILE A 1 814 ? 29.514 53.864 -13.067 1.00 6.66 ? 814 ILE A CG2 1 ATOM 6685 C CD1 . ILE A 1 814 ? 28.841 51.349 -11.364 1.00 6.64 ? 814 ILE A CD1 1 ATOM 6686 N N . LYS A 1 815 ? 27.683 51.736 -16.023 1.00 5.52 ? 815 LYS A N 1 ATOM 6687 C CA A LYS A 1 815 ? 26.372 52.000 -16.567 0.50 5.64 ? 815 LYS A CA 1 ATOM 6688 C CA B LYS A 1 815 ? 26.373 52.027 -16.567 0.50 6.08 ? 815 LYS A CA 1 ATOM 6689 C C . LYS A 1 815 ? 25.467 52.634 -15.540 1.00 5.76 ? 815 LYS A C 1 ATOM 6690 O O . LYS A 1 815 ? 25.350 52.135 -14.414 1.00 5.87 ? 815 LYS A O 1 ATOM 6691 C CB A LYS A 1 815 ? 25.779 50.669 -17.038 0.50 6.35 ? 815 LYS A CB 1 ATOM 6692 C CB B LYS A 1 815 ? 25.718 50.757 -17.110 0.50 6.62 ? 815 LYS A CB 1 ATOM 6693 C CG A LYS A 1 815 ? 24.545 50.781 -17.911 0.50 7.27 ? 815 LYS A CG 1 ATOM 6694 C CG B LYS A 1 815 ? 24.374 51.033 -17.811 0.50 6.71 ? 815 LYS A CG 1 ATOM 6695 C CD A LYS A 1 815 ? 24.236 49.401 -18.495 0.50 8.47 ? 815 LYS A CD 1 ATOM 6696 C CD B LYS A 1 815 ? 23.681 49.746 -18.230 0.50 8.72 ? 815 LYS A CD 1 ATOM 6697 C CE A LYS A 1 815 ? 22.993 49.416 -19.346 0.50 13.55 ? 815 LYS A CE 1 ATOM 6698 C CE B LYS A 1 815 ? 24.549 48.976 -19.191 0.50 9.46 ? 815 LYS A CE 1 ATOM 6699 N NZ A LYS A 1 815 ? 22.665 48.010 -19.751 0.50 14.96 ? 815 LYS A NZ 1 ATOM 6700 N NZ B LYS A 1 815 ? 23.864 47.698 -19.598 0.50 14.53 ? 815 LYS A NZ 1 ATOM 6701 N N . ARG A 1 816 ? 24.811 53.710 -15.945 1.00 5.78 ? 816 ARG A N 1 ATOM 6702 C CA . ARG A 1 816 ? 23.808 54.378 -15.161 1.00 5.97 ? 816 ARG A CA 1 ATOM 6703 C C . ARG A 1 816 ? 22.477 54.266 -15.863 1.00 5.59 ? 816 ARG A C 1 ATOM 6704 O O . ARG A 1 816 ? 22.416 54.231 -17.109 1.00 6.20 ? 816 ARG A O 1 ATOM 6705 C CB . ARG A 1 816 ? 24.121 55.890 -15.038 1.00 7.33 ? 816 ARG A CB 1 ATOM 6706 C CG . ARG A 1 816 ? 25.526 56.213 -14.526 1.00 6.33 ? 816 ARG A CG 1 ATOM 6707 C CD . ARG A 1 816 ? 25.732 55.629 -13.182 1.00 6.97 ? 816 ARG A CD 1 ATOM 6708 N NE . ARG A 1 816 ? 26.904 56.219 -12.546 1.00 5.48 ? 816 ARG A NE 1 ATOM 6709 C CZ . ARG A 1 816 ? 27.292 55.825 -11.330 1.00 5.58 ? 816 ARG A CZ 1 ATOM 6710 N NH1 . ARG A 1 816 ? 26.619 54.882 -10.706 1.00 6.21 ? 816 ARG A NH1 1 ATOM 6711 N NH2 . ARG A 1 816 ? 28.331 56.419 -10.732 1.00 5.96 ? 816 ARG A NH2 1 ATOM 6712 N N . ARG A 1 817 ? 21.426 54.276 -15.071 1.00 6.02 ? 817 ARG A N 1 ATOM 6713 C CA . ARG A 1 817 ? 20.094 54.345 -15.661 1.00 7.04 ? 817 ARG A CA 1 ATOM 6714 C C . ARG A 1 817 ? 19.348 55.461 -14.961 1.00 7.29 ? 817 ARG A C 1 ATOM 6715 O O . ARG A 1 817 ? 19.215 55.485 -13.721 1.00 7.48 ? 817 ARG A O 1 ATOM 6716 C CB . ARG A 1 817 ? 19.351 53.004 -15.470 1.00 6.91 ? 817 ARG A CB 1 ATOM 6717 C CG . ARG A 1 817 ? 17.913 53.010 -15.976 1.00 8.55 ? 817 ARG A CG 1 ATOM 6718 C CD . ARG A 1 817 ? 17.162 51.693 -15.723 1.00 9.88 ? 817 ARG A CD 1 ATOM 6719 N NE . ARG A 1 817 ? 17.685 50.633 -16.572 1.00 11.37 ? 817 ARG A NE 1 ATOM 6720 C CZ . ARG A 1 817 ? 18.427 49.617 -16.171 1.00 12.38 ? 817 ARG A CZ 1 ATOM 6721 N NH1 . ARG A 1 817 ? 18.792 49.488 -14.900 1.00 11.80 ? 817 ARG A NH1 1 ATOM 6722 N NH2 . ARG A 1 817 ? 18.821 48.722 -17.063 1.00 14.68 ? 817 ARG A NH2 1 ATOM 6723 N N A ARG A 1 818 ? 18.885 56.404 -15.764 0.50 6.64 ? 818 ARG A N 1 ATOM 6724 N N B ARG A 1 818 ? 18.885 56.404 -15.766 0.50 7.15 ? 818 ARG A N 1 ATOM 6725 C CA A ARG A 1 818 ? 18.043 57.478 -15.273 0.50 7.88 ? 818 ARG A CA 1 ATOM 6726 C CA B ARG A 1 818 ? 18.043 57.476 -15.275 0.50 8.90 ? 818 ARG A CA 1 ATOM 6727 C C A ARG A 1 818 ? 16.748 56.862 -14.786 0.50 8.30 ? 818 ARG A C 1 ATOM 6728 C C B ARG A 1 818 ? 16.748 56.861 -14.785 0.50 8.89 ? 818 ARG A C 1 ATOM 6729 O O A ARG A 1 818 ? 16.146 56.084 -15.480 0.50 9.05 ? 818 ARG A O 1 ATOM 6730 O O B ARG A 1 818 ? 16.146 56.083 -15.479 0.50 10.07 ? 818 ARG A O 1 ATOM 6731 C CB A ARG A 1 818 ? 17.732 58.452 -16.415 0.50 7.40 ? 818 ARG A CB 1 ATOM 6732 C CB B ARG A 1 818 ? 17.728 58.455 -16.414 0.50 8.69 ? 818 ARG A CB 1 ATOM 6733 C CG A ARG A 1 818 ? 16.982 59.711 -15.990 0.50 7.53 ? 818 ARG A CG 1 ATOM 6734 C CG B ARG A 1 818 ? 16.903 59.660 -15.977 0.50 9.81 ? 818 ARG A CG 1 ATOM 6735 C CD A ARG A 1 818 ? 16.386 60.445 -17.201 0.50 7.76 ? 818 ARG A CD 1 ATOM 6736 C CD B ARG A 1 818 ? 16.477 60.558 -17.143 0.50 9.88 ? 818 ARG A CD 1 ATOM 6737 N NE A ARG A 1 818 ? 15.149 59.782 -17.589 0.50 10.14 ? 818 ARG A NE 1 ATOM 6738 N NE B ARG A 1 818 ? 15.778 59.858 -18.209 0.50 14.67 ? 818 ARG A NE 1 ATOM 6739 C CZ A ARG A 1 818 ? 14.912 59.200 -18.759 0.50 10.24 ? 818 ARG A CZ 1 ATOM 6740 C CZ B ARG A 1 818 ? 16.322 59.540 -19.386 0.50 11.26 ? 818 ARG A CZ 1 ATOM 6741 N NH1 A ARG A 1 818 ? 15.797 59.218 -19.746 0.50 9.03 ? 818 ARG A NH1 1 ATOM 6742 N NH1 B ARG A 1 818 ? 17.602 59.831 -19.691 0.50 9.20 ? 818 ARG A NH1 1 ATOM 6743 N NH2 A ARG A 1 818 ? 13.732 58.599 -18.926 0.50 11.65 ? 818 ARG A NH2 1 ATOM 6744 N NH2 B ARG A 1 818 ? 15.583 58.914 -20.253 0.50 13.54 ? 818 ARG A NH2 1 ATOM 6745 N N . LEU A 1 819 ? 16.335 57.225 -13.586 1.00 8.85 ? 819 LEU A N 1 ATOM 6746 C CA . LEU A 1 819 ? 15.136 56.661 -12.990 1.00 9.83 ? 819 LEU A CA 1 ATOM 6747 C C . LEU A 1 819 ? 14.151 57.763 -12.709 1.00 10.32 ? 819 LEU A C 1 ATOM 6748 O O . LEU A 1 819 ? 14.394 58.648 -11.908 1.00 11.07 ? 819 LEU A O 1 ATOM 6749 C CB . LEU A 1 819 ? 15.473 55.936 -11.687 1.00 10.27 ? 819 LEU A CB 1 ATOM 6750 C CG . LEU A 1 819 ? 16.320 54.653 -11.870 1.00 11.34 ? 819 LEU A CG 1 ATOM 6751 C CD1 . LEU A 1 819 ? 16.765 54.129 -10.484 1.00 14.48 ? 819 LEU A CD1 1 ATOM 6752 C CD2 . LEU A 1 819 ? 15.631 53.562 -12.677 1.00 12.91 ? 819 LEU A CD2 1 ATOM 6753 N N . ASP A 1 820 ? 13.015 57.684 -13.379 1.00 12.50 ? 820 ASP A N 1 ATOM 6754 C CA . ASP A 1 820 ? 12.022 58.711 -13.123 1.00 13.25 ? 820 ASP A CA 1 ATOM 6755 C C . ASP A 1 820 ? 11.322 58.584 -11.768 1.00 11.77 ? 820 ASP A C 1 ATOM 6756 O O . ASP A 1 820 ? 10.691 59.539 -11.315 1.00 13.06 ? 820 ASP A O 1 ATOM 6757 C CB . ASP A 1 820 ? 11.070 58.815 -14.305 1.00 15.08 ? 820 ASP A CB 1 ATOM 6758 C CG . ASP A 1 820 ? 11.809 59.203 -15.600 1.00 19.69 ? 820 ASP A CG 1 ATOM 6759 O OD1 . ASP A 1 820 ? 12.850 59.952 -15.576 1.00 21.37 ? 820 ASP A OD1 1 ATOM 6760 O OD2 . ASP A 1 820 ? 11.429 58.780 -16.702 1.00 24.25 ? 820 ASP A OD2 1 ATOM 6761 N N . LYS A 1 821 ? 11.495 57.442 -11.084 1.00 10.72 ? 821 LYS A N 1 ATOM 6762 C CA . LYS A 1 821 ? 10.999 57.291 -9.713 1.00 11.24 ? 821 LYS A CA 1 ATOM 6763 C C . LYS A 1 821 ? 11.870 58.070 -8.721 1.00 12.30 ? 821 LYS A C 1 ATOM 6764 O O . LYS A 1 821 ? 11.488 58.206 -7.569 1.00 13.70 ? 821 LYS A O 1 ATOM 6765 C CB . LYS A 1 821 ? 10.875 55.816 -9.276 1.00 11.41 ? 821 LYS A CB 1 ATOM 6766 C CG . LYS A 1 821 ? 12.220 55.076 -9.161 1.00 10.40 ? 821 LYS A CG 1 ATOM 6767 C CD . LYS A 1 821 ? 12.021 53.574 -9.019 1.00 11.87 ? 821 LYS A CD 1 ATOM 6768 C CE . LYS A 1 821 ? 13.355 52.855 -9.140 1.00 11.65 ? 821 LYS A CE 1 ATOM 6769 N NZ . LYS A 1 821 ? 13.220 51.388 -9.099 1.00 12.12 ? 821 LYS A NZ 1 ATOM 6770 N N . LEU A 1 822 ? 13.019 58.597 -9.190 1.00 10.91 ? 822 LEU A N 1 ATOM 6771 C CA . LEU A 1 822 ? 13.909 59.410 -8.335 1.00 11.31 ? 822 LEU A CA 1 ATOM 6772 C C . LEU A 1 822 ? 13.895 60.839 -8.856 1.00 10.51 ? 822 LEU A C 1 ATOM 6773 O O . LEU A 1 822 ? 13.712 61.038 -10.056 1.00 10.99 ? 822 LEU A O 1 ATOM 6774 C CB . LEU A 1 822 ? 15.339 58.889 -8.378 1.00 11.86 ? 822 LEU A CB 1 ATOM 6775 C CG . LEU A 1 822 ? 15.552 57.470 -7.843 1.00 13.13 ? 822 LEU A CG 1 ATOM 6776 C CD1 . LEU A 1 822 ? 17.026 57.153 -7.939 1.00 15.66 ? 822 LEU A CD1 1 ATOM 6777 C CD2 . LEU A 1 822 ? 15.014 57.292 -6.429 1.00 16.52 ? 822 LEU A CD2 1 ATOM 6778 N N . PRO A 1 823 ? 14.098 61.805 -7.956 1.00 9.94 ? 823 PRO A N 1 ATOM 6779 C CA . PRO A 1 823 ? 14.123 63.215 -8.367 1.00 9.96 ? 823 PRO A CA 1 ATOM 6780 C C . PRO A 1 823 ? 15.359 63.519 -9.209 1.00 9.91 ? 823 PRO A C 1 ATOM 6781 O O . PRO A 1 823 ? 16.333 62.766 -9.240 1.00 8.89 ? 823 PRO A O 1 ATOM 6782 C CB . PRO A 1 823 ? 14.132 63.982 -7.049 1.00 11.49 ? 823 PRO A CB 1 ATOM 6783 C CG . PRO A 1 823 ? 14.732 63.031 -6.034 1.00 12.59 ? 823 PRO A CG 1 ATOM 6784 C CD . PRO A 1 823 ? 14.304 61.628 -6.500 1.00 10.65 ? 823 PRO A CD 1 ATOM 6785 N N . LEU A 1 824 ? 15.317 64.660 -9.903 1.00 9.30 ? 824 LEU A N 1 ATOM 6786 C CA . LEU A 1 824 ? 16.378 65.072 -10.796 1.00 9.76 ? 824 LEU A CA 1 ATOM 6787 C C . LEU A 1 824 ? 17.786 64.926 -10.174 1.00 8.83 ? 824 LEU A C 1 ATOM 6788 O O . LEU A 1 824 ? 18.703 64.392 -10.801 1.00 8.52 ? 824 LEU A O 1 ATOM 6789 C CB . LEU A 1 824 ? 16.079 66.533 -11.216 1.00 10.61 ? 824 LEU A CB 1 ATOM 6790 C CG . LEU A 1 824 ? 16.869 67.198 -12.323 1.00 10.79 ? 824 LEU A CG 1 ATOM 6791 C CD1 . LEU A 1 824 ? 16.073 68.393 -12.891 1.00 12.39 ? 824 LEU A CD1 1 ATOM 6792 C CD2 . LEU A 1 824 ? 18.260 67.655 -11.856 1.00 9.96 ? 824 LEU A CD2 1 ATOM 6793 N N . GLN A 1 825 ? 17.925 65.404 -8.952 1.00 7.93 ? 825 GLN A N 1 ATOM 6794 C CA . GLN A 1 825 ? 19.244 65.465 -8.328 1.00 7.78 ? 825 GLN A CA 1 ATOM 6795 C C . GLN A 1 825 ? 19.791 64.105 -7.984 1.00 7.54 ? 825 GLN A C 1 ATOM 6796 O O . GLN A 1 825 ? 21.016 63.971 -7.774 1.00 7.27 ? 825 GLN A O 1 ATOM 6797 C CB . GLN A 1 825 ? 19.186 66.364 -7.109 1.00 8.69 ? 825 GLN A CB 1 ATOM 6798 C CG . GLN A 1 825 ? 18.251 65.856 -5.993 1.00 7.64 ? 825 GLN A CG 1 ATOM 6799 C CD . GLN A 1 825 ? 16.794 66.323 -6.095 1.00 8.90 ? 825 GLN A CD 1 ATOM 6800 O OE1 . GLN A 1 825 ? 16.331 66.769 -7.148 1.00 9.50 ? 825 GLN A OE1 1 ATOM 6801 N NE2 . GLN A 1 825 ? 16.098 66.244 -4.984 1.00 9.33 ? 825 GLN A NE2 1 ATOM 6802 N N . ALA A 1 826 ? 18.926 63.088 -7.934 1.00 6.89 ? 826 ALA A N 1 ATOM 6803 C CA . ALA A 1 826 ? 19.391 61.721 -7.690 1.00 6.75 ? 826 ALA A CA 1 ATOM 6804 C C . ALA A 1 826 ? 19.957 61.127 -8.946 1.00 6.93 ? 826 ALA A C 1 ATOM 6805 O O . ALA A 1 826 ? 20.667 60.128 -8.890 1.00 8.49 ? 826 ALA A O 1 ATOM 6806 C CB . ALA A 1 826 ? 18.206 60.853 -7.244 1.00 7.64 ? 826 ALA A CB 1 ATOM 6807 N N . ASN A 1 827 ? 19.598 61.698 -10.096 1.00 6.65 ? 827 ASN A N 1 ATOM 6808 C CA . ASN A 1 827 ? 20.081 61.220 -11.399 1.00 6.73 ? 827 ASN A CA 1 ATOM 6809 C C . ASN A 1 827 ? 21.394 61.864 -11.845 1.00 6.02 ? 827 ASN A C 1 ATOM 6810 O O . ASN A 1 827 ? 21.903 61.588 -12.897 1.00 7.69 ? 827 ASN A O 1 ATOM 6811 C CB . ASN A 1 827 ? 18.971 61.329 -12.464 1.00 8.38 ? 827 ASN A CB 1 ATOM 6812 C CG . ASN A 1 827 ? 17.852 60.323 -12.200 1.00 11.44 ? 827 ASN A CG 1 ATOM 6813 O OD1 . ASN A 1 827 ? 18.061 59.128 -12.220 1.00 10.13 ? 827 ASN A OD1 1 ATOM 6814 N ND2 . ASN A 1 827 ? 16.663 60.824 -11.922 1.00 13.84 ? 827 ASN A ND2 1 ATOM 6815 N N . TYR A 1 828 ? 21.911 62.709 -10.949 1.00 6.07 ? 828 TYR A N 1 ATOM 6816 C CA . TYR A 1 828 ? 23.235 63.302 -11.100 1.00 5.76 ? 828 TYR A CA 1 ATOM 6817 C C . TYR A 1 828 ? 24.266 62.397 -10.502 1.00 5.87 ? 828 TYR A C 1 ATOM 6818 O O . TYR A 1 828 ? 24.028 61.814 -9.431 1.00 6.49 ? 828 TYR A O 1 ATOM 6819 C CB . TYR A 1 828 ? 23.300 64.676 -10.411 1.00 6.75 ? 828 TYR A CB 1 ATOM 6820 C CG . TYR A 1 828 ? 23.277 65.810 -11.407 1.00 5.94 ? 828 TYR A CG 1 ATOM 6821 C CD1 . TYR A 1 828 ? 22.190 66.042 -12.251 1.00 6.52 ? 828 TYR A CD1 1 ATOM 6822 C CD2 . TYR A 1 828 ? 24.372 66.643 -11.501 1.00 7.38 ? 828 TYR A CD2 1 ATOM 6823 C CE1 . TYR A 1 828 ? 22.240 67.090 -13.206 1.00 9.01 ? 828 TYR A CE1 1 ATOM 6824 C CE2 . TYR A 1 828 ? 24.426 67.660 -12.396 1.00 8.92 ? 828 TYR A CE2 1 ATOM 6825 C CZ . TYR A 1 828 ? 23.374 67.879 -13.254 1.00 6.95 ? 828 TYR A CZ 1 ATOM 6826 O OH . TYR A 1 828 ? 23.522 68.919 -14.133 1.00 9.74 ? 828 TYR A OH 1 ATOM 6827 N N . TYR A 1 829 ? 25.391 62.273 -11.195 1.00 4.65 ? 829 TYR A N 1 ATOM 6828 C CA . TYR A 1 829 ? 26.472 61.389 -10.755 1.00 5.73 ? 829 TYR A CA 1 ATOM 6829 C C . TYR A 1 829 ? 27.785 62.104 -10.897 1.00 6.17 ? 829 TYR A C 1 ATOM 6830 O O . TYR A 1 829 ? 27.871 63.100 -11.606 1.00 6.11 ? 829 TYR A O 1 ATOM 6831 C CB . TYR A 1 829 ? 26.529 60.107 -11.610 1.00 5.43 ? 829 TYR A CB 1 ATOM 6832 C CG . TYR A 1 829 ? 25.345 59.216 -11.341 1.00 5.26 ? 829 TYR A CG 1 ATOM 6833 C CD1 . TYR A 1 829 ? 25.364 58.339 -10.264 1.00 6.30 ? 829 TYR A CD1 1 ATOM 6834 C CD2 . TYR A 1 829 ? 24.181 59.265 -12.135 1.00 7.51 ? 829 TYR A CD2 1 ATOM 6835 C CE1 . TYR A 1 829 ? 24.275 57.525 -9.966 1.00 6.95 ? 829 TYR A CE1 1 ATOM 6836 C CE2 . TYR A 1 829 ? 23.107 58.447 -11.833 1.00 7.15 ? 829 TYR A CE2 1 ATOM 6837 C CZ . TYR A 1 829 ? 23.157 57.586 -10.764 1.00 6.90 ? 829 TYR A CZ 1 ATOM 6838 O OH . TYR A 1 829 ? 22.077 56.753 -10.465 1.00 7.58 ? 829 TYR A OH 1 ATOM 6839 N N . PRO A 1 830 ? 28.824 61.631 -10.232 1.00 5.65 ? 830 PRO A N 1 ATOM 6840 C CA . PRO A 1 830 ? 30.115 62.273 -10.418 1.00 5.56 ? 830 PRO A CA 1 ATOM 6841 C C . PRO A 1 830 ? 30.610 61.997 -11.823 1.00 5.86 ? 830 PRO A C 1 ATOM 6842 O O . PRO A 1 830 ? 30.397 60.882 -12.368 1.00 6.78 ? 830 PRO A O 1 ATOM 6843 C CB . PRO A 1 830 ? 31.024 61.597 -9.353 1.00 8.07 ? 830 PRO A CB 1 ATOM 6844 C CG . PRO A 1 830 ? 30.199 60.610 -8.635 1.00 9.10 ? 830 PRO A CG 1 ATOM 6845 C CD . PRO A 1 830 ? 28.843 60.489 -9.293 1.00 6.18 ? 830 PRO A CD 1 ATOM 6846 N N . ILE A 1 831 ? 31.223 63.019 -12.433 1.00 5.13 ? 831 ILE A N 1 ATOM 6847 C CA . ILE A 1 831 ? 31.898 62.866 -13.720 1.00 5.66 ? 831 ILE A CA 1 ATOM 6848 C C . ILE A 1 831 ? 33.348 63.190 -13.498 1.00 7.07 ? 831 ILE A C 1 ATOM 6849 O O . ILE A 1 831 ? 33.812 64.285 -13.814 1.00 6.11 ? 831 ILE A O 1 ATOM 6850 C CB . ILE A 1 831 ? 31.304 63.796 -14.822 1.00 5.20 ? 831 ILE A CB 1 ATOM 6851 C CG1 . ILE A 1 831 ? 29.778 63.830 -14.795 1.00 6.59 ? 831 ILE A CG1 1 ATOM 6852 C CG2 . ILE A 1 831 ? 31.847 63.384 -16.185 1.00 6.68 ? 831 ILE A CG2 1 ATOM 6853 C CD1 . ILE A 1 831 ? 29.087 62.557 -15.144 1.00 6.33 ? 831 ILE A CD1 1 ATOM 6854 N N . PRO A 1 832 ? 34.070 62.262 -12.894 1.00 5.95 ? 832 PRO A N 1 ATOM 6855 C CA . PRO A 1 832 ? 35.474 62.516 -12.578 1.00 6.24 ? 832 PRO A CA 1 ATOM 6856 C C . PRO A 1 832 ? 36.361 62.575 -13.766 1.00 7.41 ? 832 PRO A C 1 ATOM 6857 O O . PRO A 1 832 ? 37.403 63.196 -13.615 1.00 11.42 ? 832 PRO A O 1 ATOM 6858 C CB . PRO A 1 832 ? 35.867 61.409 -11.558 1.00 6.91 ? 832 PRO A CB 1 ATOM 6859 C CG . PRO A 1 832 ? 34.834 60.389 -11.715 1.00 8.26 ? 832 PRO A CG 1 ATOM 6860 C CD . PRO A 1 832 ? 33.596 60.980 -12.342 1.00 7.84 ? 832 PRO A CD 1 ATOM 6861 N N A SER A 1 833 ? 35.998 62.010 -14.915 0.50 6.43 ? 833 SER A N 1 ATOM 6862 N N B SER A 1 833 ? 36.008 61.967 -14.897 0.50 7.06 ? 833 SER A N 1 ATOM 6863 C CA A SER A 1 833 ? 36.847 62.131 -16.106 0.50 5.50 ? 833 SER A CA 1 ATOM 6864 C CA B SER A 1 833 ? 36.869 61.987 -16.085 0.50 6.79 ? 833 SER A CA 1 ATOM 6865 C C A SER A 1 833 ? 36.124 61.908 -17.431 0.50 4.89 ? 833 SER A C 1 ATOM 6866 C C B SER A 1 833 ? 36.089 61.981 -17.387 0.50 5.52 ? 833 SER A C 1 ATOM 6867 O O A SER A 1 833 ? 36.689 62.147 -18.502 0.50 4.25 ? 833 SER A O 1 ATOM 6868 O O B SER A 1 833 ? 36.573 62.447 -18.400 0.50 4.25 ? 833 SER A O 1 ATOM 6869 C CB A SER A 1 833 ? 38.076 61.209 -16.039 0.50 5.72 ? 833 SER A CB 1 ATOM 6870 C CB B SER A 1 833 ? 37.842 60.797 -16.118 0.50 7.40 ? 833 SER A CB 1 ATOM 6871 O OG A SER A 1 833 ? 37.738 59.858 -16.309 0.50 5.44 ? 833 SER A OG 1 ATOM 6872 O OG B SER A 1 833 ? 38.680 60.753 -14.985 0.50 11.25 ? 833 SER A OG 1 ATOM 6873 N N . GLY A 1 834 ? 34.889 61.439 -17.369 1.00 5.22 ? 834 GLY A N 1 ATOM 6874 C CA . GLY A 1 834 ? 34.118 61.416 -18.598 1.00 5.36 ? 834 GLY A CA 1 ATOM 6875 C C . GLY A 1 834 ? 32.767 60.779 -18.470 1.00 4.97 ? 834 GLY A C 1 ATOM 6876 O O . GLY A 1 834 ? 32.414 60.136 -17.468 1.00 5.30 ? 834 GLY A O 1 ATOM 6877 N N . MET A 1 835 ? 32.014 60.867 -19.550 1.00 5.33 ? 835 MET A N 1 ATOM 6878 C CA . MET A 1 835 ? 30.680 60.300 -19.590 1.00 5.69 ? 835 MET A CA 1 ATOM 6879 C C . MET A 1 835 ? 30.341 60.072 -21.055 1.00 5.42 ? 835 MET A C 1 ATOM 6880 O O . MET A 1 835 ? 30.900 60.714 -21.920 1.00 6.06 ? 835 MET A O 1 ATOM 6881 C CB . MET A 1 835 ? 29.668 61.266 -18.958 1.00 5.85 ? 835 MET A CB 1 ATOM 6882 C CG . MET A 1 835 ? 29.555 62.586 -19.716 1.00 7.37 ? 835 MET A CG 1 ATOM 6883 S SD . MET A 1 835 ? 28.646 63.887 -18.835 1.00 11.50 ? 835 MET A SD 1 ATOM 6884 C CE . MET A 1 835 ? 27.178 63.006 -18.362 1.00 11.84 ? 835 MET A CE 1 ATOM 6885 N N . PHE A 1 836 ? 29.425 59.143 -21.311 1.00 4.82 ? 836 PHE A N 1 ATOM 6886 C CA . PHE A 1 836 ? 29.014 58.894 -22.703 1.00 5.54 ? 836 PHE A CA 1 ATOM 6887 C C . PHE A 1 836 ? 27.588 58.401 -22.766 1.00 6.15 ? 836 PHE A C 1 ATOM 6888 O O . PHE A 1 836 ? 27.049 57.839 -21.800 1.00 5.54 ? 836 PHE A O 1 ATOM 6889 C CB . PHE A 1 836 ? 29.977 58.030 -23.512 1.00 5.63 ? 836 PHE A CB 1 ATOM 6890 C CG . PHE A 1 836 ? 30.176 56.599 -23.053 1.00 6.55 ? 836 PHE A CG 1 ATOM 6891 C CD1 . PHE A 1 836 ? 29.369 55.572 -23.554 1.00 7.57 ? 836 PHE A CD1 1 ATOM 6892 C CD2 . PHE A 1 836 ? 31.281 56.257 -22.305 1.00 7.18 ? 836 PHE A CD2 1 ATOM 6893 C CE1 . PHE A 1 836 ? 29.613 54.234 -23.189 1.00 8.41 ? 836 PHE A CE1 1 ATOM 6894 C CE2 . PHE A 1 836 ? 31.528 54.895 -21.949 1.00 6.77 ? 836 PHE A CE2 1 ATOM 6895 C CZ . PHE A 1 836 ? 30.690 53.899 -22.417 1.00 8.02 ? 836 PHE A CZ 1 ATOM 6896 N N . ILE A 1 837 ? 26.979 58.638 -23.947 1.00 5.68 ? 837 ILE A N 1 ATOM 6897 C CA . ILE A 1 837 ? 25.692 58.010 -24.299 1.00 7.16 ? 837 ILE A CA 1 ATOM 6898 C C . ILE A 1 837 ? 25.898 57.325 -25.624 1.00 6.60 ? 837 ILE A C 1 ATOM 6899 O O . ILE A 1 837 ? 26.748 57.732 -26.424 1.00 6.88 ? 837 ILE A O 1 ATOM 6900 C CB . ILE A 1 837 ? 24.526 59.013 -24.373 1.00 6.95 ? 837 ILE A CB 1 ATOM 6901 C CG1 . ILE A 1 837 ? 24.914 60.237 -25.197 1.00 8.02 ? 837 ILE A CG1 1 ATOM 6902 C CG2 . ILE A 1 837 ? 24.067 59.403 -22.991 1.00 6.83 ? 837 ILE A CG2 1 ATOM 6903 C CD1 . ILE A 1 837 ? 23.715 61.157 -25.584 1.00 7.91 ? 837 ILE A CD1 1 ATOM 6904 N N . GLU A 1 838 ? 25.128 56.263 -25.850 1.00 7.00 ? 838 GLU A N 1 ATOM 6905 C CA . GLU A 1 838 ? 25.239 55.561 -27.127 1.00 7.52 ? 838 GLU A CA 1 ATOM 6906 C C . GLU A 1 838 ? 23.933 54.905 -27.487 1.00 8.36 ? 838 GLU A C 1 ATOM 6907 O O . GLU A 1 838 ? 23.089 54.647 -26.645 1.00 7.64 ? 838 GLU A O 1 ATOM 6908 C CB . GLU A 1 838 ? 26.339 54.512 -27.119 1.00 7.93 ? 838 GLU A CB 1 ATOM 6909 C CG . GLU A 1 838 ? 26.139 53.441 -26.079 1.00 9.33 ? 838 GLU A CG 1 ATOM 6910 C CD . GLU A 1 838 ? 27.233 52.402 -26.091 1.00 13.39 ? 838 GLU A CD 1 ATOM 6911 O OE1 . GLU A 1 838 ? 28.261 52.559 -26.798 1.00 14.09 ? 838 GLU A OE1 1 ATOM 6912 O OE2 . GLU A 1 838 ? 27.054 51.373 -25.403 1.00 14.07 ? 838 GLU A OE2 1 ATOM 6913 N N . ASP A 1 839 ? 23.833 54.602 -28.782 1.00 8.48 ? 839 ASP A N 1 ATOM 6914 C CA . ASP A 1 839 ? 22.791 53.680 -29.250 1.00 8.53 ? 839 ASP A CA 1 ATOM 6915 C C . ASP A 1 839 ? 23.466 52.605 -30.079 1.00 8.53 ? 839 ASP A C 1 ATOM 6916 O O . ASP A 1 839 ? 24.660 52.376 -29.954 1.00 10.06 ? 839 ASP A O 1 ATOM 6917 C CB . ASP A 1 839 ? 21.638 54.389 -29.970 1.00 8.82 ? 839 ASP A CB 1 ATOM 6918 C CG . ASP A 1 839 ? 22.060 55.140 -31.231 1.00 10.33 ? 839 ASP A CG 1 ATOM 6919 O OD1 . ASP A 1 839 ? 23.101 54.802 -31.816 1.00 11.58 ? 839 ASP A OD1 1 ATOM 6920 O OD2 . ASP A 1 839 ? 21.350 56.085 -31.672 1.00 15.57 ? 839 ASP A OD2 1 ATOM 6921 N N . ALA A 1 840 ? 22.691 51.881 -30.899 1.00 9.97 ? 840 ALA A N 1 ATOM 6922 C CA . ALA A 1 840 ? 23.291 50.815 -31.687 1.00 11.69 ? 840 ALA A CA 1 ATOM 6923 C C . ALA A 1 840 ? 24.400 51.305 -32.606 1.00 10.99 ? 840 ALA A C 1 ATOM 6924 O O . ALA A 1 840 ? 25.338 50.586 -32.893 1.00 12.84 ? 840 ALA A O 1 ATOM 6925 C CB . ALA A 1 840 ? 22.227 50.079 -32.513 1.00 12.48 ? 840 ALA A CB 1 ATOM 6926 N N . ASN A 1 841 ? 24.269 52.538 -33.086 1.00 10.12 ? 841 ASN A N 1 ATOM 6927 C CA . ASN A 1 841 ? 25.147 53.054 -34.140 1.00 9.62 ? 841 ASN A CA 1 ATOM 6928 C C . ASN A 1 841 ? 26.131 54.150 -33.778 1.00 8.48 ? 841 ASN A C 1 ATOM 6929 O O . ASN A 1 841 ? 27.188 54.234 -34.378 1.00 9.81 ? 841 ASN A O 1 ATOM 6930 C CB . ASN A 1 841 ? 24.305 53.523 -35.328 1.00 10.16 ? 841 ASN A CB 1 ATOM 6931 C CG . ASN A 1 841 ? 23.542 52.390 -35.954 1.00 12.16 ? 841 ASN A CG 1 ATOM 6932 O OD1 . ASN A 1 841 ? 24.070 51.297 -36.101 1.00 14.82 ? 841 ASN A OD1 1 ATOM 6933 N ND2 . ASN A 1 841 ? 22.282 52.640 -36.278 1.00 16.00 ? 841 ASN A ND2 1 ATOM 6934 N N . THR A 1 842 ? 25.748 54.974 -32.801 1.00 8.80 ? 842 THR A N 1 ATOM 6935 C CA . THR A 1 842 ? 26.464 56.222 -32.518 1.00 8.83 ? 842 THR A CA 1 ATOM 6936 C C . THR A 1 842 ? 26.761 56.331 -31.026 1.00 7.31 ? 842 THR A C 1 ATOM 6937 O O . THR A 1 842 ? 25.915 55.967 -30.221 1.00 9.02 ? 842 THR A O 1 ATOM 6938 C CB . THR A 1 842 ? 25.572 57.391 -32.938 1.00 9.52 ? 842 THR A CB 1 ATOM 6939 O OG1 . THR A 1 842 ? 25.217 57.223 -34.329 1.00 12.57 ? 842 THR A OG1 1 ATOM 6940 C CG2 . THR A 1 842 ? 26.322 58.741 -32.898 1.00 11.80 ? 842 THR A CG2 1 ATOM 6941 N N . ARG A 1 843 ? 27.939 56.895 -30.710 1.00 7.58 ? 843 ARG A N 1 ATOM 6942 C CA . ARG A 1 843 ? 28.268 57.243 -29.310 1.00 7.08 ? 843 ARG A CA 1 ATOM 6943 C C . ARG A 1 843 ? 28.774 58.671 -29.275 1.00 6.87 ? 843 ARG A C 1 ATOM 6944 O O . ARG A 1 843 ? 29.497 59.094 -30.188 1.00 7.95 ? 843 ARG A O 1 ATOM 6945 C CB . ARG A 1 843 ? 29.337 56.295 -28.774 1.00 7.41 ? 843 ARG A CB 1 ATOM 6946 C CG . ARG A 1 843 ? 29.762 56.546 -27.327 1.00 7.27 ? 843 ARG A CG 1 ATOM 6947 C CD . ARG A 1 843 ? 30.928 55.711 -26.943 1.00 7.45 ? 843 ARG A CD 1 ATOM 6948 N NE . ARG A 1 843 ? 30.537 54.328 -26.655 1.00 8.22 ? 843 ARG A NE 1 ATOM 6949 C CZ . ARG A 1 843 ? 31.357 53.479 -26.061 1.00 8.41 ? 843 ARG A CZ 1 ATOM 6950 N NH1 . ARG A 1 843 ? 32.585 53.865 -25.728 1.00 7.34 ? 843 ARG A NH1 1 ATOM 6951 N NH2 . ARG A 1 843 ? 30.939 52.256 -25.753 1.00 8.89 ? 843 ARG A NH2 1 ATOM 6952 N N . LEU A 1 844 ? 28.397 59.378 -28.206 1.00 6.20 ? 844 LEU A N 1 ATOM 6953 C CA . LEU A 1 844 ? 28.979 60.697 -27.919 1.00 6.88 ? 844 LEU A CA 1 ATOM 6954 C C . LEU A 1 844 ? 29.628 60.624 -26.530 1.00 6.30 ? 844 LEU A C 1 ATOM 6955 O O . LEU A 1 844 ? 28.935 60.310 -25.556 1.00 7.09 ? 844 LEU A O 1 ATOM 6956 C CB . LEU A 1 844 ? 27.933 61.801 -27.948 1.00 8.04 ? 844 LEU A CB 1 ATOM 6957 C CG . LEU A 1 844 ? 28.532 63.235 -27.830 1.00 8.86 ? 844 LEU A CG 1 ATOM 6958 C CD1 . LEU A 1 844 ? 29.416 63.601 -29.019 1.00 12.10 ? 844 LEU A CD1 1 ATOM 6959 C CD2 . LEU A 1 844 ? 27.390 64.235 -27.663 1.00 11.65 ? 844 LEU A CD2 1 ATOM 6960 N N . THR A 1 845 ? 30.936 60.862 -26.503 1.00 5.92 ? 845 THR A N 1 ATOM 6961 C CA . THR A 1 845 ? 31.706 60.813 -25.250 1.00 5.85 ? 845 THR A CA 1 ATOM 6962 C C . THR A 1 845 ? 32.230 62.221 -24.969 1.00 5.40 ? 845 THR A C 1 ATOM 6963 O O . THR A 1 845 ? 32.823 62.862 -25.844 1.00 6.50 ? 845 THR A O 1 ATOM 6964 C CB . THR A 1 845 ? 32.900 59.889 -25.384 1.00 5.27 ? 845 THR A CB 1 ATOM 6965 O OG1 . THR A 1 845 ? 32.461 58.573 -25.814 1.00 7.87 ? 845 THR A OG1 1 ATOM 6966 C CG2 . THR A 1 845 ? 33.603 59.647 -24.020 1.00 7.74 ? 845 THR A CG2 1 ATOM 6967 N N . LEU A 1 846 ? 32.005 62.672 -23.746 1.00 6.25 ? 846 LEU A N 1 ATOM 6968 C CA . LEU A 1 846 ? 32.561 63.940 -23.267 1.00 6.05 ? 846 LEU A CA 1 ATOM 6969 C C . LEU A 1 846 ? 33.634 63.608 -22.222 1.00 5.63 ? 846 LEU A C 1 ATOM 6970 O O . LEU A 1 846 ? 33.292 63.002 -21.191 1.00 5.93 ? 846 LEU A O 1 ATOM 6971 C CB . LEU A 1 846 ? 31.472 64.825 -22.677 1.00 7.83 ? 846 LEU A CB 1 ATOM 6972 C CG . LEU A 1 846 ? 31.934 66.197 -22.187 1.00 8.23 ? 846 LEU A CG 1 ATOM 6973 C CD1 . LEU A 1 846 ? 32.409 67.043 -23.373 1.00 11.32 ? 846 LEU A CD1 1 ATOM 6974 C CD2 . LEU A 1 846 ? 30.790 66.910 -21.496 1.00 12.08 ? 846 LEU A CD2 1 ATOM 6975 N N . LEU A 1 847 ? 34.889 63.924 -22.490 1.00 5.65 ? 847 LEU A N 1 ATOM 6976 C CA . LEU A 1 847 ? 35.977 63.716 -21.509 1.00 4.43 ? 847 LEU A CA 1 ATOM 6977 C C . LEU A 1 847 ? 36.201 65.029 -20.790 1.00 6.16 ? 847 LEU A C 1 ATOM 6978 O O . LEU A 1 847 ? 36.094 66.097 -21.409 1.00 5.60 ? 847 LEU A O 1 ATOM 6979 C CB . LEU A 1 847 ? 37.277 63.277 -22.172 1.00 5.09 ? 847 LEU A CB 1 ATOM 6980 C CG . LEU A 1 847 ? 37.237 61.924 -22.876 1.00 5.45 ? 847 LEU A CG 1 ATOM 6981 C CD1 . LEU A 1 847 ? 36.624 60.779 -22.046 1.00 6.40 ? 847 LEU A CD1 1 ATOM 6982 C CD2 . LEU A 1 847 ? 36.580 62.017 -24.271 1.00 6.12 ? 847 LEU A CD2 1 ATOM 6983 N N . THR A 1 848 ? 36.570 64.965 -19.509 1.00 4.90 ? 848 THR A N 1 ATOM 6984 C CA A THR A 1 848 ? 36.770 66.200 -18.711 0.50 5.40 ? 848 THR A CA 1 ATOM 6985 C CA B THR A 1 848 ? 36.735 66.168 -18.708 0.50 5.36 ? 848 THR A CA 1 ATOM 6986 C C . THR A 1 848 ? 38.156 66.271 -18.115 1.00 6.76 ? 848 THR A C 1 ATOM 6987 O O . THR A 1 848 ? 38.794 65.240 -17.809 1.00 7.11 ? 848 THR A O 1 ATOM 6988 C CB A THR A 1 848 ? 35.860 66.322 -17.508 0.50 7.03 ? 848 THR A CB 1 ATOM 6989 C CB B THR A 1 848 ? 35.679 66.158 -17.623 0.50 6.53 ? 848 THR A CB 1 ATOM 6990 O OG1 A THR A 1 848 ? 36.166 65.244 -16.605 0.50 6.37 ? 848 THR A OG1 1 ATOM 6991 O OG1 B THR A 1 848 ? 34.389 65.862 -18.177 0.50 12.02 ? 848 THR A OG1 1 ATOM 6992 C CG2 A THR A 1 848 ? 34.410 66.173 -17.815 0.50 8.77 ? 848 THR A CG2 1 ATOM 6993 C CG2 B THR A 1 848 ? 35.546 67.512 -16.998 0.50 3.79 ? 848 THR A CG2 1 ATOM 6994 N N . GLY A 1 849 ? 38.632 67.499 -17.939 1.00 5.87 ? 849 GLY A N 1 ATOM 6995 C CA . GLY A 1 849 ? 39.893 67.725 -17.281 1.00 5.33 ? 849 GLY A CA 1 ATOM 6996 C C . GLY A 1 849 ? 39.729 68.091 -15.809 1.00 5.04 ? 849 GLY A C 1 ATOM 6997 O O . GLY A 1 849 ? 40.682 68.528 -15.186 1.00 5.03 ? 849 GLY A O 1 ATOM 6998 N N . GLN A 1 850 ? 38.522 67.957 -15.285 1.00 4.57 ? 850 GLN A N 1 ATOM 6999 C CA . GLN A 1 850 ? 38.206 68.264 -13.889 1.00 4.41 ? 850 GLN A CA 1 ATOM 7000 C C . GLN A 1 850 ? 36.954 67.490 -13.513 1.00 4.35 ? 850 GLN A C 1 ATOM 7001 O O . GLN A 1 850 ? 36.072 67.286 -14.353 1.00 5.18 ? 850 GLN A O 1 ATOM 7002 C CB . GLN A 1 850 ? 37.955 69.779 -13.727 1.00 5.73 ? 850 GLN A CB 1 ATOM 7003 C CG . GLN A 1 850 ? 36.827 70.389 -14.636 1.00 5.31 ? 850 GLN A CG 1 ATOM 7004 C CD . GLN A 1 850 ? 37.225 70.507 -16.116 1.00 5.21 ? 850 GLN A CD 1 ATOM 7005 O OE1 . GLN A 1 850 ? 38.336 70.921 -16.443 1.00 6.48 ? 850 GLN A OE1 1 ATOM 7006 N NE2 . GLN A 1 850 ? 36.300 70.158 -16.994 1.00 5.12 ? 850 GLN A NE2 1 ATOM 7007 N N . PRO A 1 851 ? 36.831 67.061 -12.266 1.00 4.06 ? 851 PRO A N 1 ATOM 7008 C CA . PRO A 1 851 ? 35.604 66.367 -11.837 1.00 4.33 ? 851 PRO A CA 1 ATOM 7009 C C . PRO A 1 851 ? 34.482 67.345 -11.650 1.00 4.32 ? 851 PRO A C 1 ATOM 7010 O O . PRO A 1 851 ? 34.650 68.387 -10.999 1.00 4.85 ? 851 PRO A O 1 ATOM 7011 C CB . PRO A 1 851 ? 36.003 65.732 -10.478 1.00 5.45 ? 851 PRO A CB 1 ATOM 7012 C CG . PRO A 1 851 ? 37.104 66.664 -9.940 1.00 4.21 ? 851 PRO A CG 1 ATOM 7013 C CD . PRO A 1 851 ? 37.824 67.147 -11.183 1.00 4.65 ? 851 PRO A CD 1 ATOM 7014 N N . LEU A 1 852 ? 33.328 66.999 -12.211 1.00 4.77 ? 852 LEU A N 1 ATOM 7015 C CA . LEU A 1 852 ? 32.129 67.808 -12.096 1.00 5.69 ? 852 LEU A CA 1 ATOM 7016 C C . LEU A 1 852 ? 30.906 66.896 -12.006 1.00 7.15 ? 852 LEU A C 1 ATOM 7017 O O . LEU A 1 852 ? 31.037 65.699 -12.159 1.00 10.79 ? 852 LEU A O 1 ATOM 7018 C CB . LEU A 1 852 ? 31.994 68.709 -13.334 1.00 6.31 ? 852 LEU A CB 1 ATOM 7019 C CG . LEU A 1 852 ? 33.106 69.764 -13.503 1.00 5.68 ? 852 LEU A CG 1 ATOM 7020 C CD1 . LEU A 1 852 ? 33.104 70.358 -14.927 1.00 8.05 ? 852 LEU A CD1 1 ATOM 7021 C CD2 . LEU A 1 852 ? 33.069 70.880 -12.484 1.00 7.29 ? 852 LEU A CD2 1 ATOM 7022 N N . GLY A 1 853 ? 29.746 67.435 -11.710 1.00 5.70 ? 853 GLY A N 1 ATOM 7023 C CA . GLY A 1 853 ? 28.545 66.603 -11.644 1.00 5.73 ? 853 GLY A CA 1 ATOM 7024 C C . GLY A 1 853 ? 27.828 66.600 -12.972 1.00 4.43 ? 853 GLY A C 1 ATOM 7025 O O . GLY A 1 853 ? 27.894 67.593 -13.734 1.00 5.13 ? 853 GLY A O 1 ATOM 7026 N N . GLY A 1 854 ? 27.158 65.511 -13.289 1.00 4.76 ? 854 GLY A N 1 ATOM 7027 C CA . GLY A 1 854 ? 26.454 65.488 -14.548 1.00 5.27 ? 854 GLY A CA 1 ATOM 7028 C C . GLY A 1 854 ? 25.461 64.368 -14.663 1.00 4.92 ? 854 GLY A C 1 ATOM 7029 O O . GLY A 1 854 ? 25.275 63.551 -13.764 1.00 5.87 ? 854 GLY A O 1 ATOM 7030 N N . SER A 1 855 ? 24.778 64.357 -15.809 1.00 6.36 ? 855 SER A N 1 ATOM 7031 C CA . SER A 1 855 ? 23.713 63.375 -15.982 1.00 6.73 ? 855 SER A CA 1 ATOM 7032 C C . SER A 1 855 ? 23.327 63.320 -17.447 1.00 7.62 ? 855 SER A C 1 ATOM 7033 O O . SER A 1 855 ? 23.868 64.001 -18.306 1.00 7.52 ? 855 SER A O 1 ATOM 7034 C CB . SER A 1 855 ? 22.472 63.791 -15.196 1.00 7.57 ? 855 SER A CB 1 ATOM 7035 O OG . SER A 1 855 ? 21.479 62.765 -15.189 1.00 9.23 ? 855 SER A OG 1 ATOM 7036 N N . SER A 1 856 ? 22.383 62.425 -17.726 1.00 7.15 ? 856 SER A N 1 ATOM 7037 C CA . SER A 1 856 ? 21.631 62.427 -18.996 1.00 7.64 ? 856 SER A CA 1 ATOM 7038 C C . SER A 1 856 ? 20.165 62.431 -18.601 1.00 7.66 ? 856 SER A C 1 ATOM 7039 O O . SER A 1 856 ? 19.632 61.384 -18.194 1.00 8.37 ? 856 SER A O 1 ATOM 7040 C CB . SER A 1 856 ? 22.006 61.192 -19.817 1.00 6.75 ? 856 SER A CB 1 ATOM 7041 O OG . SER A 1 856 ? 21.124 61.057 -20.937 1.00 7.84 ? 856 SER A OG 1 ATOM 7042 N N . LEU A 1 857 ? 19.496 63.591 -18.667 1.00 8.52 ? 857 LEU A N 1 ATOM 7043 C CA . LEU A 1 857 ? 18.143 63.710 -18.126 1.00 8.85 ? 857 LEU A CA 1 ATOM 7044 C C . LEU A 1 857 ? 17.057 63.430 -19.149 1.00 9.67 ? 857 LEU A C 1 ATOM 7045 O O . LEU A 1 857 ? 15.884 63.375 -18.810 1.00 10.25 ? 857 LEU A O 1 ATOM 7046 C CB . LEU A 1 857 ? 17.916 65.081 -17.456 1.00 9.29 ? 857 LEU A CB 1 ATOM 7047 C CG . LEU A 1 857 ? 18.729 65.321 -16.192 1.00 10.22 ? 857 LEU A CG 1 ATOM 7048 C CD1 . LEU A 1 857 ? 18.557 66.775 -15.758 1.00 12.85 ? 857 LEU A CD1 1 ATOM 7049 C CD2 . LEU A 1 857 ? 18.292 64.375 -15.094 1.00 11.94 ? 857 LEU A CD2 1 ATOM 7050 N N . ALA A 1 858 ? 17.494 63.213 -20.372 1.00 7.96 ? 858 ALA A N 1 ATOM 7051 C CA . ALA A 1 858 ? 16.602 62.763 -21.473 1.00 8.85 ? 858 ALA A CA 1 ATOM 7052 C C . ALA A 1 858 ? 17.410 62.041 -22.511 1.00 9.72 ? 858 ALA A C 1 ATOM 7053 O O . ALA A 1 858 ? 18.611 62.245 -22.625 1.00 8.96 ? 858 ALA A O 1 ATOM 7054 C CB . ALA A 1 858 ? 15.871 63.941 -22.123 1.00 9.56 ? 858 ALA A CB 1 ATOM 7055 N N . SER A 1 859 ? 16.762 61.164 -23.279 1.00 9.13 ? 859 SER A N 1 ATOM 7056 C CA . SER A 1 859 ? 17.404 60.400 -24.301 1.00 9.30 ? 859 SER A CA 1 ATOM 7057 C C . SER A 1 859 ? 18.141 61.358 -25.210 1.00 9.25 ? 859 SER A C 1 ATOM 7058 O O . SER A 1 859 ? 17.601 62.422 -25.588 1.00 10.59 ? 859 SER A O 1 ATOM 7059 C CB . SER A 1 859 ? 16.342 59.576 -25.063 1.00 9.75 ? 859 SER A CB 1 ATOM 7060 O OG . SER A 1 859 ? 16.921 58.815 -26.062 1.00 10.59 ? 859 SER A OG 1 ATOM 7061 N N . GLY A 1 860 ? 19.363 60.994 -25.544 1.00 8.55 ? 860 GLY A N 1 ATOM 7062 C CA . GLY A 1 860 ? 20.196 61.781 -26.434 1.00 8.83 ? 860 GLY A CA 1 ATOM 7063 C C . GLY A 1 860 ? 20.899 62.984 -25.787 1.00 8.75 ? 860 GLY A C 1 ATOM 7064 O O . GLY A 1 860 ? 21.638 63.696 -26.476 1.00 8.86 ? 860 GLY A O 1 ATOM 7065 N N . GLU A 1 861 ? 20.713 63.193 -24.483 1.00 9.12 ? 861 GLU A N 1 ATOM 7066 C CA . GLU A 1 861 ? 21.349 64.342 -23.812 1.00 9.20 ? 861 GLU A CA 1 ATOM 7067 C C . GLU A 1 861 ? 22.513 63.958 -22.924 1.00 8.05 ? 861 GLU A C 1 ATOM 7068 O O . GLU A 1 861 ? 22.526 62.870 -22.341 1.00 9.04 ? 861 GLU A O 1 ATOM 7069 C CB . GLU A 1 861 ? 20.380 65.112 -22.942 1.00 9.80 ? 861 GLU A CB 1 ATOM 7070 C CG . GLU A 1 861 ? 19.250 65.777 -23.704 1.00 12.90 ? 861 GLU A CG 1 ATOM 7071 C CD . GLU A 1 861 ? 18.343 66.603 -22.773 1.00 13.33 ? 861 GLU A CD 1 ATOM 7072 O OE1 . GLU A 1 861 ? 18.526 66.642 -21.506 1.00 15.57 ? 861 GLU A OE1 1 ATOM 7073 O OE2 . GLU A 1 861 ? 17.382 67.253 -23.287 1.00 18.28 ? 861 GLU A OE2 1 ATOM 7074 N N . LEU A 1 862 ? 23.462 64.869 -22.801 1.00 7.35 ? 862 LEU A N 1 ATOM 7075 C CA . LEU A 1 862 ? 24.498 64.798 -21.743 1.00 7.22 ? 862 LEU A CA 1 ATOM 7076 C C . LEU A 1 862 ? 24.496 66.175 -21.127 1.00 7.32 ? 862 LEU A C 1 ATOM 7077 O O . LEU A 1 862 ? 24.320 67.168 -21.829 1.00 6.88 ? 862 LEU A O 1 ATOM 7078 C CB . LEU A 1 862 ? 25.871 64.551 -22.363 1.00 8.05 ? 862 LEU A CB 1 ATOM 7079 C CG . LEU A 1 862 ? 26.230 63.169 -22.925 1.00 8.92 ? 862 LEU A CG 1 ATOM 7080 C CD1 . LEU A 1 862 ? 27.612 63.172 -23.568 1.00 12.04 ? 862 LEU A CD1 1 ATOM 7081 C CD2 . LEU A 1 862 ? 26.079 62.100 -21.825 1.00 10.78 ? 862 LEU A CD2 1 ATOM 7082 N N . GLU A 1 863 ? 24.720 66.291 -19.830 1.00 5.85 ? 863 GLU A N 1 ATOM 7083 C CA . GLU A 1 863 ? 24.946 67.601 -19.232 1.00 6.22 ? 863 GLU A CA 1 ATOM 7084 C C . GLU A 1 863 ? 25.926 67.487 -18.101 1.00 5.72 ? 863 GLU A C 1 ATOM 7085 O O . GLU A 1 863 ? 26.046 66.453 -17.411 1.00 5.54 ? 863 GLU A O 1 ATOM 7086 C CB . GLU A 1 863 ? 23.661 68.251 -18.768 1.00 7.34 ? 863 GLU A CB 1 ATOM 7087 C CG . GLU A 1 863 ? 23.033 67.645 -17.518 1.00 9.28 ? 863 GLU A CG 1 ATOM 7088 C CD . GLU A 1 863 ? 21.740 68.355 -17.157 1.00 9.25 ? 863 GLU A CD 1 ATOM 7089 O OE1 . GLU A 1 863 ? 20.812 68.381 -18.036 1.00 10.44 ? 863 GLU A OE1 1 ATOM 7090 O OE2 . GLU A 1 863 ? 21.621 68.871 -16.032 1.00 9.07 ? 863 GLU A OE2 1 ATOM 7091 N N . ILE A 1 864 ? 26.604 68.607 -17.900 1.00 5.87 ? 864 ILE A N 1 ATOM 7092 C CA A ILE A 1 864 ? 27.615 68.674 -16.862 0.50 5.09 ? 864 ILE A CA 1 ATOM 7093 C CA B ILE A 1 864 ? 27.668 68.701 -16.883 0.50 6.21 ? 864 ILE A CA 1 ATOM 7094 C C . ILE A 1 864 ? 27.631 70.068 -16.239 1.00 5.85 ? 864 ILE A C 1 ATOM 7095 O O . ILE A 1 864 ? 27.644 71.089 -16.958 1.00 5.69 ? 864 ILE A O 1 ATOM 7096 C CB A ILE A 1 864 ? 28.977 68.232 -17.460 0.50 5.09 ? 864 ILE A CB 1 ATOM 7097 C CB B ILE A 1 864 ? 29.074 68.520 -17.500 0.50 6.58 ? 864 ILE A CB 1 ATOM 7098 C CG1 A ILE A 1 864 ? 30.009 67.912 -16.355 0.50 5.85 ? 864 ILE A CG1 1 ATOM 7099 C CG1 B ILE A 1 864 ? 29.251 67.138 -18.109 0.50 6.86 ? 864 ILE A CG1 1 ATOM 7100 C CG2 A ILE A 1 864 ? 29.431 69.205 -18.588 0.50 2.63 ? 864 ILE A CG2 1 ATOM 7101 C CG2 B ILE A 1 864 ? 30.154 68.784 -16.464 0.50 7.62 ? 864 ILE A CG2 1 ATOM 7102 C CD1 A ILE A 1 864 ? 31.225 67.189 -16.901 0.50 5.60 ? 864 ILE A CD1 1 ATOM 7103 C CD1 B ILE A 1 864 ? 30.728 66.824 -18.522 0.50 8.19 ? 864 ILE A CD1 1 ATOM 7104 N N . MET A 1 865 ? 27.575 70.104 -14.925 1.00 5.81 ? 865 MET A N 1 ATOM 7105 C CA . MET A 1 865 ? 27.503 71.372 -14.233 1.00 6.22 ? 865 MET A CA 1 ATOM 7106 C C . MET A 1 865 ? 28.858 72.068 -14.264 1.00 7.29 ? 865 MET A C 1 ATOM 7107 O O . MET A 1 865 ? 29.900 71.423 -14.132 1.00 8.10 ? 865 MET A O 1 ATOM 7108 C CB . MET A 1 865 ? 27.057 71.112 -12.802 1.00 7.50 ? 865 MET A CB 1 ATOM 7109 C CG . MET A 1 865 ? 26.503 72.326 -12.102 1.00 7.87 ? 865 MET A CG 1 ATOM 7110 S SD . MET A 1 865 ? 24.867 72.795 -12.793 1.00 10.24 ? 865 MET A SD 1 ATOM 7111 C CE . MET A 1 865 ? 23.875 71.449 -11.998 1.00 13.04 ? 865 MET A CE 1 ATOM 7112 N N . GLN A 1 866 ? 28.843 73.393 -14.430 1.00 6.11 ? 866 GLN A N 1 ATOM 7113 C CA . GLN A 1 866 ? 30.062 74.193 -14.563 1.00 5.89 ? 866 GLN A CA 1 ATOM 7114 C C . GLN A 1 866 ? 30.456 74.898 -13.264 1.00 6.20 ? 866 GLN A C 1 ATOM 7115 O O . GLN A 1 866 ? 31.625 74.908 -12.896 1.00 6.97 ? 866 GLN A O 1 ATOM 7116 C CB . GLN A 1 866 ? 29.889 75.248 -15.671 1.00 6.27 ? 866 GLN A CB 1 ATOM 7117 C CG . GLN A 1 866 ? 29.558 74.621 -17.043 1.00 8.11 ? 866 GLN A CG 1 ATOM 7118 C CD . GLN A 1 866 ? 30.604 73.658 -17.505 1.00 8.88 ? 866 GLN A CD 1 ATOM 7119 O OE1 . GLN A 1 866 ? 31.733 74.041 -17.842 1.00 9.35 ? 866 GLN A OE1 1 ATOM 7120 N NE2 . GLN A 1 866 ? 30.255 72.388 -17.520 1.00 8.70 ? 866 GLN A NE2 1 ATOM 7121 N N . ASP A 1 867 ? 29.486 75.496 -12.579 1.00 6.49 ? 867 ASP A N 1 ATOM 7122 C CA . ASP A 1 867 ? 29.739 76.148 -11.288 1.00 6.45 ? 867 ASP A CA 1 ATOM 7123 C C . ASP A 1 867 ? 28.402 76.363 -10.642 1.00 5.99 ? 867 ASP A C 1 ATOM 7124 O O . ASP A 1 867 ? 27.333 76.252 -11.309 1.00 6.29 ? 867 ASP A O 1 ATOM 7125 C CB . ASP A 1 867 ? 30.520 77.465 -11.418 1.00 7.31 ? 867 ASP A CB 1 ATOM 7126 C CG . ASP A 1 867 ? 31.227 77.861 -10.132 1.00 7.95 ? 867 ASP A CG 1 ATOM 7127 O OD1 . ASP A 1 867 ? 31.107 77.185 -9.077 1.00 7.81 ? 867 ASP A OD1 1 ATOM 7128 O OD2 . ASP A 1 867 ? 31.967 78.869 -10.172 1.00 10.08 ? 867 ASP A OD2 1 ATOM 7129 N N . ARG A 1 868 ? 28.461 76.641 -9.357 1.00 6.67 ? 868 ARG A N 1 ATOM 7130 C CA . ARG A 1 868 ? 27.262 76.870 -8.579 1.00 6.68 ? 868 ARG A CA 1 ATOM 7131 C C . ARG A 1 868 ? 27.578 77.898 -7.500 1.00 7.15 ? 868 ARG A C 1 ATOM 7132 O O . ARG A 1 868 ? 28.640 77.858 -6.879 1.00 7.62 ? 868 ARG A O 1 ATOM 7133 C CB . ARG A 1 868 ? 26.714 75.565 -8.008 1.00 7.40 ? 868 ARG A CB 1 ATOM 7134 C CG . ARG A 1 868 ? 27.673 74.758 -7.141 1.00 8.71 ? 868 ARG A CG 1 ATOM 7135 C CD . ARG A 1 868 ? 27.411 73.249 -7.182 1.00 8.60 ? 868 ARG A CD 1 ATOM 7136 N NE . ARG A 1 868 ? 26.046 72.980 -6.756 1.00 7.45 ? 868 ARG A NE 1 ATOM 7137 C CZ . ARG A 1 868 ? 25.707 72.723 -5.496 1.00 6.90 ? 868 ARG A CZ 1 ATOM 7138 N NH1 . ARG A 1 868 ? 26.643 72.608 -4.532 1.00 6.75 ? 868 ARG A NH1 1 ATOM 7139 N NH2 . ARG A 1 868 ? 24.426 72.552 -5.200 1.00 7.85 ? 868 ARG A NH2 1 ATOM 7140 N N . ARG A 1 869 ? 26.636 78.826 -7.291 1.00 6.55 ? 869 ARG A N 1 ATOM 7141 C CA . ARG A 1 869 ? 26.818 79.910 -6.322 1.00 7.66 ? 869 ARG A CA 1 ATOM 7142 C C . ARG A 1 869 ? 25.537 79.929 -5.533 1.00 8.07 ? 869 ARG A C 1 ATOM 7143 O O . ARG A 1 869 ? 24.447 80.106 -6.098 1.00 8.67 ? 869 ARG A O 1 ATOM 7144 C CB . ARG A 1 869 ? 27.067 81.218 -7.055 1.00 8.40 ? 869 ARG A CB 1 ATOM 7145 C CG . ARG A 1 869 ? 27.231 82.372 -6.118 1.00 9.55 ? 869 ARG A CG 1 ATOM 7146 C CD . ARG A 1 869 ? 27.637 83.636 -6.857 1.00 12.42 ? 869 ARG A CD 1 ATOM 7147 N NE . ARG A 1 869 ? 27.744 84.801 -5.976 1.00 14.47 ? 869 ARG A NE 1 ATOM 7148 C CZ . ARG A 1 869 ? 28.850 85.148 -5.351 1.00 13.76 ? 869 ARG A CZ 1 ATOM 7149 N NH1 . ARG A 1 869 ? 29.944 84.418 -5.472 1.00 14.40 ? 869 ARG A NH1 1 ATOM 7150 N NH2 . ARG A 1 869 ? 28.862 86.242 -4.588 1.00 18.25 ? 869 ARG A NH2 1 ATOM 7151 N N . LEU A 1 870 ? 25.679 79.658 -4.243 1.00 8.85 ? 870 LEU A N 1 ATOM 7152 C CA . LEU A 1 870 ? 24.529 79.365 -3.376 1.00 9.39 ? 870 LEU A CA 1 ATOM 7153 C C . LEU A 1 870 ? 24.593 80.187 -2.119 1.00 10.60 ? 870 LEU A C 1 ATOM 7154 O O . LEU A 1 870 ? 25.568 80.139 -1.367 1.00 10.74 ? 870 LEU A O 1 ATOM 7155 C CB . LEU A 1 870 ? 24.543 77.886 -2.972 1.00 9.38 ? 870 LEU A CB 1 ATOM 7156 C CG . LEU A 1 870 ? 24.441 77.039 -4.244 1.00 13.73 ? 870 LEU A CG 1 ATOM 7157 C CD1 . LEU A 1 870 ? 24.927 75.656 -4.029 1.00 17.18 ? 870 LEU A CD1 1 ATOM 7158 C CD2 . LEU A 1 870 ? 23.104 77.077 -4.956 1.00 12.62 ? 870 LEU A CD2 1 ATOM 7159 N N . ALA A 1 871 ? 23.508 80.905 -1.864 1.00 10.76 ? 871 ALA A N 1 ATOM 7160 C CA . ALA A 1 871 ? 23.526 81.781 -0.717 1.00 12.90 ? 871 ALA A CA 1 ATOM 7161 C C . ALA A 1 871 ? 23.334 81.078 0.636 1.00 14.05 ? 871 ALA A C 1 ATOM 7162 O O . ALA A 1 871 ? 23.752 81.588 1.677 1.00 17.21 ? 871 ALA A O 1 ATOM 7163 C CB . ALA A 1 871 ? 22.474 82.900 -0.879 1.00 13.75 ? 871 ALA A CB 1 ATOM 7164 N N . SER A 1 872 ? 22.714 79.907 0.619 1.00 14.06 ? 872 SER A N 1 ATOM 7165 C CA . SER A 1 872 ? 22.264 79.282 1.855 1.00 14.80 ? 872 SER A CA 1 ATOM 7166 C C . SER A 1 872 ? 23.159 78.135 2.287 1.00 13.70 ? 872 SER A C 1 ATOM 7167 O O . SER A 1 872 ? 23.812 77.479 1.453 1.00 13.78 ? 872 SER A O 1 ATOM 7168 C CB . SER A 1 872 ? 20.836 78.751 1.673 1.00 15.79 ? 872 SER A CB 1 ATOM 7169 O OG . SER A 1 872 ? 19.963 79.845 1.432 1.00 20.93 ? 872 SER A OG 1 ATOM 7170 N N . ASP A 1 873 ? 23.210 77.924 3.600 1.00 13.76 ? 873 ASP A N 1 ATOM 7171 C CA . ASP A 1 873 ? 23.747 76.697 4.183 1.00 13.75 ? 873 ASP A CA 1 ATOM 7172 C C . ASP A 1 873 ? 22.734 75.553 4.017 1.00 14.43 ? 873 ASP A C 1 ATOM 7173 O O . ASP A 1 873 ? 21.528 75.782 4.084 1.00 15.64 ? 873 ASP A O 1 ATOM 7174 C CB . ASP A 1 873 ? 24.040 76.925 5.657 1.00 13.49 ? 873 ASP A CB 1 ATOM 7175 C CG . ASP A 1 873 ? 24.476 75.662 6.357 1.00 15.73 ? 873 ASP A CG 1 ATOM 7176 O OD1 . ASP A 1 873 ? 25.587 75.169 6.040 1.00 15.82 ? 873 ASP A OD1 1 ATOM 7177 O OD2 . ASP A 1 873 ? 23.767 75.099 7.219 1.00 15.74 ? 873 ASP A OD2 1 ATOM 7178 N N . ASP A 1 874 ? 23.219 74.333 3.795 1.00 12.64 ? 874 ASP A N 1 ATOM 7179 C CA . ASP A 1 874 ? 22.331 73.199 3.586 1.00 10.72 ? 874 ASP A CA 1 ATOM 7180 C C . ASP A 1 874 ? 22.333 72.234 4.793 1.00 10.28 ? 874 ASP A C 1 ATOM 7181 O O . ASP A 1 874 ? 22.113 71.027 4.627 1.00 11.69 ? 874 ASP A O 1 ATOM 7182 C CB . ASP A 1 874 ? 22.686 72.499 2.270 1.00 10.47 ? 874 ASP A CB 1 ATOM 7183 C CG . ASP A 1 874 ? 24.159 72.170 2.153 1.00 10.71 ? 874 ASP A CG 1 ATOM 7184 O OD1 . ASP A 1 874 ? 25.003 72.518 3.028 1.00 12.59 ? 874 ASP A OD1 1 ATOM 7185 O OD2 . ASP A 1 874 ? 24.531 71.538 1.156 1.00 9.84 ? 874 ASP A OD2 1 ATOM 7186 N N . GLU A 1 875 ? 22.590 72.759 5.991 1.00 10.32 ? 875 GLU A N 1 ATOM 7187 C CA . GLU A 1 875 ? 22.281 72.031 7.240 1.00 13.03 ? 875 GLU A CA 1 ATOM 7188 C C . GLU A 1 875 ? 23.081 70.769 7.443 1.00 12.57 ? 875 GLU A C 1 ATOM 7189 O O . GLU A 1 875 ? 22.608 69.820 8.106 1.00 12.78 ? 875 GLU A O 1 ATOM 7190 C CB . GLU A 1 875 ? 20.781 71.669 7.370 1.00 13.99 ? 875 GLU A CB 1 ATOM 7191 C CG . GLU A 1 875 ? 19.783 72.758 7.031 1.00 17.03 ? 875 GLU A CG 1 ATOM 7192 C CD . GLU A 1 875 ? 18.332 72.276 7.082 1.00 19.28 ? 875 GLU A CD 1 ATOM 7193 O OE1 . GLU A 1 875 ? 18.020 71.098 6.713 1.00 24.00 ? 875 GLU A OE1 1 ATOM 7194 O OE2 . GLU A 1 875 ? 17.486 73.105 7.483 1.00 27.03 ? 875 GLU A OE2 1 ATOM 7195 N N . ARG A 1 876 ? 24.290 70.740 6.885 1.00 9.99 ? 876 ARG A N 1 ATOM 7196 C CA . ARG A 1 876 ? 25.179 69.592 7.084 1.00 11.08 ? 876 ARG A CA 1 ATOM 7197 C C . ARG A 1 876 ? 26.436 69.968 7.869 1.00 10.89 ? 876 ARG A C 1 ATOM 7198 O O . ARG A 1 876 ? 27.410 69.195 7.881 1.00 12.93 ? 876 ARG A O 1 ATOM 7199 C CB . ARG A 1 876 ? 25.555 68.935 5.753 1.00 9.60 ? 876 ARG A CB 1 ATOM 7200 C CG . ARG A 1 876 ? 24.355 68.313 4.974 1.00 10.81 ? 876 ARG A CG 1 ATOM 7201 C CD . ARG A 1 876 ? 23.539 67.383 5.840 1.00 11.91 ? 876 ARG A CD 1 ATOM 7202 N NE . ARG A 1 876 ? 22.442 66.667 5.174 1.00 10.42 ? 876 ARG A NE 1 ATOM 7203 C CZ . ARG A 1 876 ? 21.250 67.191 4.886 1.00 10.00 ? 876 ARG A CZ 1 ATOM 7204 N NH1 . ARG A 1 876 ? 20.992 68.489 5.080 1.00 8.96 ? 876 ARG A NH1 1 ATOM 7205 N NH2 . ARG A 1 876 ? 20.326 66.396 4.353 1.00 9.08 ? 876 ARG A NH2 1 ATOM 7206 N N . GLY A 1 877 ? 26.415 71.125 8.532 1.00 11.45 ? 877 GLY A N 1 ATOM 7207 C CA . GLY A 1 877 ? 27.502 71.508 9.426 1.00 11.89 ? 877 GLY A CA 1 ATOM 7208 C C . GLY A 1 877 ? 28.495 72.513 8.886 1.00 11.10 ? 877 GLY A C 1 ATOM 7209 O O . GLY A 1 877 ? 29.327 73.015 9.662 1.00 11.96 ? 877 GLY A O 1 ATOM 7210 N N . LEU A 1 878 ? 28.395 72.859 7.601 1.00 10.34 ? 878 LEU A N 1 ATOM 7211 C CA . LEU A 1 878 ? 29.369 73.787 7.030 1.00 11.45 ? 878 LEU A CA 1 ATOM 7212 C C . LEU A 1 878 ? 29.169 75.207 7.540 1.00 11.14 ? 878 LEU A C 1 ATOM 7213 O O . LEU A 1 878 ? 30.140 75.925 7.773 1.00 11.21 ? 878 LEU A O 1 ATOM 7214 C CB . LEU A 1 878 ? 29.335 73.719 5.501 1.00 10.87 ? 878 LEU A CB 1 ATOM 7215 C CG . LEU A 1 878 ? 30.141 74.759 4.718 1.00 11.30 ? 878 LEU A CG 1 ATOM 7216 C CD1 . LEU A 1 878 ? 31.621 74.727 5.166 1.00 11.90 ? 878 LEU A CD1 1 ATOM 7217 C CD2 . LEU A 1 878 ? 30.025 74.568 3.223 1.00 13.26 ? 878 LEU A CD2 1 ATOM 7218 N N . GLY A 1 879 ? 27.902 75.609 7.685 1.00 10.80 ? 879 GLY A N 1 ATOM 7219 C CA . GLY A 1 879 ? 27.561 76.900 8.255 1.00 11.20 ? 879 GLY A CA 1 ATOM 7220 C C . GLY A 1 879 ? 27.832 78.068 7.335 1.00 11.58 ? 879 GLY A C 1 ATOM 7221 O O . GLY A 1 879 ? 28.018 79.188 7.801 1.00 12.91 ? 879 GLY A O 1 ATOM 7222 N N . GLN A 1 880 ? 27.826 77.819 6.029 1.00 10.90 ? 880 GLN A N 1 ATOM 7223 C CA . GLN A 1 880 ? 27.902 78.899 5.049 1.00 10.92 ? 880 GLN A CA 1 ATOM 7224 C C . GLN A 1 880 ? 27.409 78.372 3.722 1.00 11.70 ? 880 GLN A C 1 ATOM 7225 O O . GLN A 1 880 ? 27.348 77.156 3.525 1.00 11.99 ? 880 GLN A O 1 ATOM 7226 C CB . GLN A 1 880 ? 29.342 79.450 4.918 1.00 10.61 ? 880 GLN A CB 1 ATOM 7227 C CG . GLN A 1 880 ? 30.340 78.418 4.397 1.00 11.45 ? 880 GLN A CG 1 ATOM 7228 C CD . GLN A 1 880 ? 31.634 79.034 3.880 1.00 11.35 ? 880 GLN A CD 1 ATOM 7229 O OE1 . GLN A 1 880 ? 32.526 79.382 4.648 1.00 11.27 ? 880 GLN A OE1 1 ATOM 7230 N NE2 . GLN A 1 880 ? 31.716 79.195 2.579 1.00 12.04 ? 880 GLN A NE2 1 ATOM 7231 N N . GLY A 1 881 ? 27.080 79.303 2.832 1.00 13.21 ? 881 GLY A N 1 ATOM 7232 C CA . GLY A 1 881 ? 26.813 78.978 1.448 1.00 12.99 ? 881 GLY A CA 1 ATOM 7233 C C . GLY A 1 881 ? 28.097 78.845 0.645 1.00 12.60 ? 881 GLY A C 1 ATOM 7234 O O . GLY A 1 881 ? 29.220 78.686 1.181 1.00 13.27 ? 881 GLY A O 1 ATOM 7235 N N . VAL A 1 882 ? 27.925 78.906 -0.668 1.00 10.89 ? 882 VAL A N 1 ATOM 7236 C CA . VAL A 1 882 ? 29.056 78.889 -1.576 1.00 11.34 ? 882 VAL A CA 1 ATOM 7237 C C . VAL A 1 882 ? 29.013 80.210 -2.332 1.00 11.27 ? 882 VAL A C 1 ATOM 7238 O O . VAL A 1 882 ? 28.267 80.368 -3.291 1.00 10.31 ? 882 VAL A O 1 ATOM 7239 C CB . VAL A 1 882 ? 29.023 77.687 -2.508 1.00 11.15 ? 882 VAL A CB 1 ATOM 7240 C CG1 . VAL A 1 882 ? 30.158 77.778 -3.512 1.00 12.38 ? 882 VAL A CG1 1 ATOM 7241 C CG2 . VAL A 1 882 ? 29.167 76.430 -1.665 1.00 11.94 ? 882 VAL A CG2 1 ATOM 7242 N N . LEU A 1 883 ? 29.785 81.182 -1.841 1.00 11.22 ? 883 LEU A N 1 ATOM 7243 C CA . LEU A 1 883 ? 29.767 82.522 -2.432 1.00 11.97 ? 883 LEU A CA 1 ATOM 7244 C C . LEU A 1 883 ? 31.167 83.013 -2.750 1.00 12.43 ? 883 LEU A C 1 ATOM 7245 O O . LEU A 1 883 ? 31.356 84.212 -2.923 1.00 15.20 ? 883 LEU A O 1 ATOM 7246 C CB . LEU A 1 883 ? 29.074 83.520 -1.492 1.00 12.61 ? 883 LEU A CB 1 ATOM 7247 C CG . LEU A 1 883 ? 27.574 83.278 -1.245 1.00 12.70 ? 883 LEU A CG 1 ATOM 7248 C CD1 . LEU A 1 883 ? 27.006 84.179 -0.114 1.00 13.07 ? 883 LEU A CD1 1 ATOM 7249 C CD2 . LEU A 1 883 ? 26.769 83.507 -2.508 1.00 12.67 ? 883 LEU A CD2 1 ATOM 7250 N N . ASP A 1 884 ? 32.131 82.104 -2.817 1.00 11.30 ? 884 ASP A N 1 ATOM 7251 C CA . ASP A 1 884 ? 33.549 82.438 -3.040 1.00 10.80 ? 884 ASP A CA 1 ATOM 7252 C C . ASP A 1 884 ? 34.060 81.991 -4.419 1.00 11.15 ? 884 ASP A C 1 ATOM 7253 O O . ASP A 1 884 ? 35.248 81.708 -4.623 1.00 10.64 ? 884 ASP A O 1 ATOM 7254 C CB . ASP A 1 884 ? 34.419 81.842 -1.921 1.00 11.61 ? 884 ASP A CB 1 ATOM 7255 C CG . ASP A 1 884 ? 34.204 80.340 -1.712 1.00 13.92 ? 884 ASP A CG 1 ATOM 7256 O OD1 . ASP A 1 884 ? 33.388 79.675 -2.430 1.00 12.20 ? 884 ASP A OD1 1 ATOM 7257 O OD2 . ASP A 1 884 ? 34.834 79.758 -0.775 1.00 15.63 ? 884 ASP A OD2 1 ATOM 7258 N N . ASN A 1 885 ? 33.142 81.942 -5.373 1.00 9.69 ? 885 ASN A N 1 ATOM 7259 C CA . ASN A 1 885 ? 33.479 81.558 -6.729 1.00 10.80 ? 885 ASN A CA 1 ATOM 7260 C C . ASN A 1 885 ? 34.556 82.405 -7.305 1.00 10.86 ? 885 ASN A C 1 ATOM 7261 O O . ASN A 1 885 ? 34.652 83.601 -7.001 1.00 11.82 ? 885 ASN A O 1 ATOM 7262 C CB . ASN A 1 885 ? 32.239 81.657 -7.615 1.00 9.62 ? 885 ASN A CB 1 ATOM 7263 C CG . ASN A 1 885 ? 31.043 80.985 -6.991 1.00 10.40 ? 885 ASN A CG 1 ATOM 7264 O OD1 . ASN A 1 885 ? 30.392 81.538 -6.104 1.00 11.51 ? 885 ASN A OD1 1 ATOM 7265 N ND2 . ASN A 1 885 ? 30.714 79.800 -7.492 1.00 9.43 ? 885 ASN A ND2 1 ATOM 7266 N N . LYS A 1 886 ? 35.342 81.803 -8.174 1.00 11.23 ? 886 LYS A N 1 ATOM 7267 C CA . LYS A 1 886 ? 36.313 82.561 -8.955 1.00 11.42 ? 886 LYS A CA 1 ATOM 7268 C C . LYS A 1 886 ? 36.426 81.944 -10.327 1.00 10.60 ? 886 LYS A C 1 ATOM 7269 O O . LYS A 1 886 ? 36.055 80.781 -10.546 1.00 10.36 ? 886 LYS A O 1 ATOM 7270 C CB . LYS A 1 886 ? 37.661 82.587 -8.245 1.00 13.81 ? 886 LYS A CB 1 ATOM 7271 C CG . LYS A 1 886 ? 38.198 81.208 -7.926 1.00 14.36 ? 886 LYS A CG 1 ATOM 7272 C CD . LYS A 1 886 ? 39.251 81.225 -6.797 1.00 20.38 ? 886 LYS A CD 1 ATOM 7273 C CE . LYS A 1 886 ? 40.603 81.581 -7.369 1.00 20.84 ? 886 LYS A CE 1 ATOM 7274 N NZ . LYS A 1 886 ? 41.702 81.564 -6.354 1.00 22.26 ? 886 LYS A NZ 1 ATOM 7275 N N . PRO A 1 887 ? 36.869 82.729 -11.290 1.00 9.06 ? 887 PRO A N 1 ATOM 7276 C CA . PRO A 1 887 ? 36.939 82.240 -12.662 1.00 9.39 ? 887 PRO A CA 1 ATOM 7277 C C . PRO A 1 887 ? 37.736 80.966 -12.774 1.00 8.87 ? 887 PRO A C 1 ATOM 7278 O O . PRO A 1 887 ? 38.803 80.854 -12.189 1.00 9.93 ? 887 PRO A O 1 ATOM 7279 C CB . PRO A 1 887 ? 37.584 83.401 -13.417 1.00 10.16 ? 887 PRO A CB 1 ATOM 7280 C CG . PRO A 1 887 ? 37.089 84.608 -12.613 1.00 10.84 ? 887 PRO A CG 1 ATOM 7281 C CD . PRO A 1 887 ? 37.173 84.177 -11.197 1.00 11.11 ? 887 PRO A CD 1 ATOM 7282 N N . VAL A 1 888 ? 37.186 80.003 -13.510 1.00 7.67 ? 888 VAL A N 1 ATOM 7283 C CA . VAL A 1 888 ? 37.857 78.732 -13.694 1.00 6.55 ? 888 VAL A CA 1 ATOM 7284 C C . VAL A 1 888 ? 37.787 78.364 -15.170 1.00 6.45 ? 888 VAL A C 1 ATOM 7285 O O . VAL A 1 888 ? 36.739 78.577 -15.823 1.00 6.46 ? 888 VAL A O 1 ATOM 7286 C CB . VAL A 1 888 ? 37.237 77.612 -12.778 1.00 8.19 ? 888 VAL A CB 1 ATOM 7287 C CG1 . VAL A 1 888 ? 35.740 77.549 -12.971 1.00 8.38 ? 888 VAL A CG1 1 ATOM 7288 C CG2 . VAL A 1 888 ? 37.894 76.285 -13.077 1.00 8.26 ? 888 VAL A CG2 1 ATOM 7289 N N . LEU A 1 889 ? 38.891 77.838 -15.696 1.00 5.57 ? 889 LEU A N 1 ATOM 7290 C CA . LEU A 1 889 ? 38.907 77.340 -17.055 1.00 6.42 ? 889 LEU A CA 1 ATOM 7291 C C . LEU A 1 889 ? 38.700 75.827 -17.092 1.00 6.61 ? 889 LEU A C 1 ATOM 7292 O O . LEU A 1 889 ? 39.600 75.044 -16.766 1.00 7.55 ? 889 LEU A O 1 ATOM 7293 C CB . LEU A 1 889 ? 40.209 77.721 -17.755 1.00 6.82 ? 889 LEU A CB 1 ATOM 7294 C CG . LEU A 1 889 ? 40.278 77.270 -19.222 1.00 7.56 ? 889 LEU A CG 1 ATOM 7295 C CD1 . LEU A 1 889 ? 39.429 78.156 -20.125 1.00 9.87 ? 889 LEU A CD1 1 ATOM 7296 C CD2 . LEU A 1 889 ? 41.729 77.249 -19.727 1.00 12.43 ? 889 LEU A CD2 1 ATOM 7297 N N . HIS A 1 890 ? 37.503 75.425 -17.452 1.00 5.28 ? 890 HIS A N 1 ATOM 7298 C CA . HIS A 1 890 ? 37.199 73.993 -17.581 1.00 5.13 ? 890 HIS A CA 1 ATOM 7299 C C . HIS A 1 890 ? 37.573 73.529 -18.949 1.00 5.33 ? 890 HIS A C 1 ATOM 7300 O O . HIS A 1 890 ? 37.329 74.256 -19.939 1.00 6.24 ? 890 HIS A O 1 ATOM 7301 C CB . HIS A 1 890 ? 35.704 73.769 -17.394 1.00 5.84 ? 890 HIS A CB 1 ATOM 7302 C CG . HIS A 1 890 ? 35.250 73.914 -15.975 1.00 6.69 ? 890 HIS A CG 1 ATOM 7303 N ND1 . HIS A 1 890 ? 36.048 73.551 -14.899 1.00 8.65 ? 890 HIS A ND1 1 ATOM 7304 C CD2 . HIS A 1 890 ? 34.075 74.333 -15.445 1.00 7.84 ? 890 HIS A CD2 1 ATOM 7305 C CE1 . HIS A 1 890 ? 35.373 73.737 -13.775 1.00 9.83 ? 890 HIS A CE1 1 ATOM 7306 N NE2 . HIS A 1 890 ? 34.176 74.212 -14.078 1.00 8.74 ? 890 HIS A NE2 1 ATOM 7307 N N . ILE A 1 891 ? 38.084 72.312 -19.059 1.00 5.20 ? 891 ILE A N 1 ATOM 7308 C CA . ILE A 1 891 ? 38.519 71.783 -20.342 1.00 5.36 ? 891 ILE A CA 1 ATOM 7309 C C . ILE A 1 891 ? 37.880 70.426 -20.618 1.00 4.80 ? 891 ILE A C 1 ATOM 7310 O O . ILE A 1 891 ? 37.623 69.641 -19.660 1.00 4.96 ? 891 ILE A O 1 ATOM 7311 C CB . ILE A 1 891 ? 40.076 71.746 -20.427 1.00 5.57 ? 891 ILE A CB 1 ATOM 7312 C CG1 . ILE A 1 891 ? 40.659 70.702 -19.467 1.00 6.85 ? 891 ILE A CG1 1 ATOM 7313 C CG2 . ILE A 1 891 ? 40.658 73.172 -20.202 1.00 8.22 ? 891 ILE A CG2 1 ATOM 7314 C CD1 . ILE A 1 891 ? 42.176 70.502 -19.594 1.00 8.44 ? 891 ILE A CD1 1 ATOM 7315 N N . TYR A 1 892 ? 37.613 70.161 -21.889 1.00 5.01 ? 892 TYR A N 1 ATOM 7316 C CA . TYR A 1 892 ? 36.954 68.934 -22.318 1.00 4.92 ? 892 TYR A CA 1 ATOM 7317 C C . TYR A 1 892 ? 37.407 68.501 -23.678 1.00 5.11 ? 892 TYR A C 1 ATOM 7318 O O . TYR A 1 892 ? 37.953 69.296 -24.440 1.00 5.10 ? 892 TYR A O 1 ATOM 7319 C CB . TYR A 1 892 ? 35.432 69.150 -22.448 1.00 5.21 ? 892 TYR A CB 1 ATOM 7320 C CG . TYR A 1 892 ? 34.757 69.811 -21.264 1.00 4.99 ? 892 TYR A CG 1 ATOM 7321 C CD1 . TYR A 1 892 ? 34.698 71.195 -21.135 1.00 6.35 ? 892 TYR A CD1 1 ATOM 7322 C CD2 . TYR A 1 892 ? 34.196 69.032 -20.253 1.00 6.79 ? 892 TYR A CD2 1 ATOM 7323 C CE1 . TYR A 1 892 ? 34.097 71.791 -20.059 1.00 6.03 ? 892 TYR A CE1 1 ATOM 7324 C CE2 . TYR A 1 892 ? 33.614 69.619 -19.154 1.00 6.22 ? 892 TYR A CE2 1 ATOM 7325 C CZ . TYR A 1 892 ? 33.552 70.987 -19.055 1.00 5.70 ? 892 TYR A CZ 1 ATOM 7326 O OH . TYR A 1 892 ? 32.922 71.529 -17.965 1.00 7.07 ? 892 TYR A OH 1 ATOM 7327 N N . ARG A 1 893 ? 37.145 67.228 -23.996 1.00 4.91 ? 893 ARG A N 1 ATOM 7328 C CA . ARG A 1 893 ? 37.210 66.775 -25.390 1.00 5.96 ? 893 ARG A CA 1 ATOM 7329 C C . ARG A 1 893 ? 35.870 66.129 -25.696 1.00 6.17 ? 893 ARG A C 1 ATOM 7330 O O . ARG A 1 893 ? 35.274 65.497 -24.858 1.00 6.48 ? 893 ARG A O 1 ATOM 7331 C CB . ARG A 1 893 ? 38.296 65.736 -25.599 1.00 6.97 ? 893 ARG A CB 1 ATOM 7332 C CG . ARG A 1 893 ? 39.719 66.212 -25.415 1.00 7.95 ? 893 ARG A CG 1 ATOM 7333 C CD . ARG A 1 893 ? 40.179 67.235 -26.474 1.00 7.61 ? 893 ARG A CD 1 ATOM 7334 N NE . ARG A 1 893 ? 40.246 66.704 -27.834 1.00 8.86 ? 893 ARG A NE 1 ATOM 7335 C CZ . ARG A 1 893 ? 41.232 65.956 -28.331 1.00 8.36 ? 893 ARG A CZ 1 ATOM 7336 N NH1 . ARG A 1 893 ? 42.252 65.588 -27.547 1.00 11.21 ? 893 ARG A NH1 1 ATOM 7337 N NH2 . ARG A 1 893 ? 41.211 65.547 -29.608 1.00 12.75 ? 893 ARG A NH2 1 ATOM 7338 N N . LEU A 1 894 ? 35.425 66.287 -26.944 1.00 7.31 ? 894 LEU A N 1 ATOM 7339 C CA . LEU A 1 894 ? 34.123 65.805 -27.376 1.00 7.81 ? 894 LEU A CA 1 ATOM 7340 C C . LEU A 1 894 ? 34.326 64.840 -28.519 1.00 7.29 ? 894 LEU A C 1 ATOM 7341 O O . LEU A 1 894 ? 34.807 65.247 -29.576 1.00 9.04 ? 894 LEU A O 1 ATOM 7342 C CB . LEU A 1 894 ? 33.291 67.001 -27.860 1.00 8.72 ? 894 LEU A CB 1 ATOM 7343 C CG . LEU A 1 894 ? 31.835 66.655 -28.206 1.00 10.82 ? 894 LEU A CG 1 ATOM 7344 C CD1 . LEU A 1 894 ? 31.079 66.121 -26.995 1.00 13.57 ? 894 LEU A CD1 1 ATOM 7345 C CD2 . LEU A 1 894 ? 31.150 67.871 -28.788 1.00 13.90 ? 894 LEU A CD2 1 ATOM 7346 N N . VAL A 1 895 ? 33.997 63.561 -28.306 1.00 6.90 ? 895 VAL A N 1 ATOM 7347 C CA . VAL A 1 895 ? 34.282 62.535 -29.292 1.00 8.09 ? 895 VAL A CA 1 ATOM 7348 C C . VAL A 1 895 ? 32.980 61.898 -29.779 1.00 8.66 ? 895 VAL A C 1 ATOM 7349 O O . VAL A 1 895 ? 32.295 61.219 -29.018 1.00 8.77 ? 895 VAL A O 1 ATOM 7350 C CB . VAL A 1 895 ? 35.167 61.448 -28.677 1.00 8.27 ? 895 VAL A CB 1 ATOM 7351 C CG1 . VAL A 1 895 ? 35.598 60.485 -29.756 1.00 10.93 ? 895 VAL A CG1 1 ATOM 7352 C CG2 . VAL A 1 895 ? 36.424 62.073 -28.026 1.00 10.14 ? 895 VAL A CG2 1 ATOM 7353 N N . LEU A 1 896 ? 32.628 62.158 -31.036 1.00 8.49 ? 896 LEU A N 1 ATOM 7354 C CA . LEU A 1 896 ? 31.483 61.520 -31.680 1.00 8.59 ? 896 LEU A CA 1 ATOM 7355 C C . LEU A 1 896 ? 32.022 60.383 -32.530 1.00 9.17 ? 896 LEU A C 1 ATOM 7356 O O . LEU A 1 896 ? 32.975 60.566 -33.294 1.00 9.89 ? 896 LEU A O 1 ATOM 7357 C CB . LEU A 1 896 ? 30.752 62.528 -32.578 1.00 8.96 ? 896 LEU A CB 1 ATOM 7358 C CG . LEU A 1 896 ? 29.578 61.937 -33.375 1.00 10.96 ? 896 LEU A CG 1 ATOM 7359 C CD1 . LEU A 1 896 ? 28.407 61.755 -32.455 1.00 12.80 ? 896 LEU A CD1 1 ATOM 7360 C CD2 . LEU A 1 896 ? 29.217 62.864 -34.533 1.00 12.03 ? 896 LEU A CD2 1 ATOM 7361 N N . GLU A 1 897 ? 31.435 59.197 -32.382 1.00 8.98 ? 897 GLU A N 1 ATOM 7362 C CA . GLU A 1 897 ? 31.984 58.013 -33.050 1.00 9.60 ? 897 GLU A CA 1 ATOM 7363 C C . GLU A 1 897 ? 30.877 57.106 -33.531 1.00 9.43 ? 897 GLU A C 1 ATOM 7364 O O . GLU A 1 897 ? 29.839 57.026 -32.892 1.00 9.13 ? 897 GLU A O 1 ATOM 7365 C CB . GLU A 1 897 ? 32.889 57.220 -32.104 1.00 12.43 ? 897 GLU A CB 1 ATOM 7366 C CG . GLU A 1 897 ? 34.021 58.022 -31.508 1.00 16.02 ? 897 GLU A CG 1 ATOM 7367 C CD . GLU A 1 897 ? 34.764 57.227 -30.445 1.00 18.58 ? 897 GLU A CD 1 ATOM 7368 O OE1 . GLU A 1 897 ? 34.189 56.985 -29.325 1.00 21.21 ? 897 GLU A OE1 1 ATOM 7369 O OE2 . GLU A 1 897 ? 35.930 56.896 -30.758 1.00 20.55 ? 897 GLU A OE2 1 ATOM 7370 N N . LYS A 1 898 ? 31.135 56.415 -34.640 1.00 11.52 ? 898 LYS A N 1 ATOM 7371 C CA . LYS A 1 898 ? 30.308 55.296 -35.079 1.00 13.27 ? 898 LYS A CA 1 ATOM 7372 C C . LYS A 1 898 ? 30.727 54.043 -34.322 1.00 13.56 ? 898 LYS A C 1 ATOM 7373 O O . LYS A 1 898 ? 31.911 53.699 -34.275 1.00 15.82 ? 898 LYS A O 1 ATOM 7374 C CB . LYS A 1 898 ? 30.431 55.094 -36.586 1.00 14.32 ? 898 LYS A CB 1 ATOM 7375 C CG . LYS A 1 898 ? 29.815 56.223 -37.403 1.00 18.81 ? 898 LYS A CG 1 ATOM 7376 C CD . LYS A 1 898 ? 28.568 56.858 -36.724 1.00 24.14 ? 898 LYS A CD 1 ATOM 7377 C CE . LYS A 1 898 ? 27.216 56.255 -37.159 1.00 25.51 ? 898 LYS A CE 1 ATOM 7378 N NZ . LYS A 1 898 ? 27.137 54.743 -37.244 1.00 26.43 ? 898 LYS A NZ 1 ATOM 7379 N N . VAL A 1 899 ? 29.762 53.379 -33.699 1.00 12.38 ? 899 VAL A N 1 ATOM 7380 C CA . VAL A 1 899 ? 30.086 52.232 -32.853 1.00 12.33 ? 899 VAL A CA 1 ATOM 7381 C C . VAL A 1 899 ? 29.368 50.959 -33.273 1.00 13.12 ? 899 VAL A C 1 ATOM 7382 O O . VAL A 1 899 ? 29.396 49.975 -32.553 1.00 12.00 ? 899 VAL A O 1 ATOM 7383 C CB . VAL A 1 899 ? 29.816 52.522 -31.360 1.00 12.46 ? 899 VAL A CB 1 ATOM 7384 C CG1 . VAL A 1 899 ? 30.826 53.545 -30.836 1.00 15.25 ? 899 VAL A CG1 1 ATOM 7385 C CG2 . VAL A 1 899 ? 28.389 52.981 -31.133 1.00 10.71 ? 899 VAL A CG2 1 ATOM 7386 N N . ASN A 1 900 ? 28.736 50.975 -34.443 1.00 13.01 ? 900 ASN A N 1 ATOM 7387 C CA . ASN A 1 900 ? 27.969 49.807 -34.873 1.00 14.23 ? 900 ASN A CA 1 ATOM 7388 C C . ASN A 1 900 ? 28.834 48.569 -35.066 1.00 14.09 ? 900 ASN A C 1 ATOM 7389 O O . ASN A 1 900 ? 28.313 47.449 -34.952 1.00 15.49 ? 900 ASN A O 1 ATOM 7390 C CB . ASN A 1 900 ? 27.193 50.100 -36.164 1.00 13.99 ? 900 ASN A CB 1 ATOM 7391 C CG . ASN A 1 900 ? 28.064 50.635 -37.267 1.00 17.19 ? 900 ASN A CG 1 ATOM 7392 O OD1 . ASN A 1 900 ? 28.623 51.735 -37.181 1.00 22.98 ? 900 ASN A OD1 1 ATOM 7393 N ND2 . ASN A 1 900 ? 28.166 49.865 -38.351 1.00 21.25 ? 900 ASN A ND2 1 ATOM 7394 N N . ASN A 1 901 ? 30.129 48.774 -35.314 1.00 12.88 ? 901 ASN A N 1 ATOM 7395 C CA . ASN A 1 901 ? 31.109 47.675 -35.507 1.00 13.64 ? 901 ASN A CA 1 ATOM 7396 C C . ASN A 1 901 ? 31.858 47.269 -34.258 1.00 13.46 ? 901 ASN A C 1 ATOM 7397 O O . ASN A 1 901 ? 32.601 46.294 -34.285 1.00 13.21 ? 901 ASN A O 1 ATOM 7398 C CB . ASN A 1 901 ? 32.129 48.049 -36.572 1.00 15.29 ? 901 ASN A CB 1 ATOM 7399 C CG . ASN A 1 901 ? 31.558 48.000 -37.953 1.00 18.85 ? 901 ASN A CG 1 ATOM 7400 O OD1 . ASN A 1 901 ? 30.761 47.119 -38.281 1.00 23.10 ? 901 ASN A OD1 1 ATOM 7401 N ND2 . ASN A 1 901 ? 31.970 48.947 -38.794 1.00 24.06 ? 901 ASN A ND2 1 ATOM 7402 N N . CYS A 1 902 ? 31.631 47.971 -33.155 1.00 12.91 ? 902 CYS A N 1 ATOM 7403 C CA . CYS A 1 902 ? 32.367 47.706 -31.919 1.00 13.32 ? 902 CYS A CA 1 ATOM 7404 C C . CYS A 1 902 ? 31.832 46.499 -31.192 1.00 12.61 ? 902 CYS A C 1 ATOM 7405 O O . CYS A 1 902 ? 30.625 46.307 -31.095 1.00 13.41 ? 902 CYS A O 1 ATOM 7406 C CB . CYS A 1 902 ? 32.287 48.895 -30.975 1.00 13.92 ? 902 CYS A CB 1 ATOM 7407 S SG . CYS A 1 902 ? 33.096 50.355 -31.633 1.00 19.13 ? 902 CYS A SG 1 ATOM 7408 N N . VAL A 1 903 ? 32.734 45.716 -30.620 1.00 11.60 ? 903 VAL A N 1 ATOM 7409 C CA . VAL A 1 903 ? 32.328 44.607 -29.761 1.00 12.03 ? 903 VAL A CA 1 ATOM 7410 C C . VAL A 1 903 ? 32.083 45.171 -28.352 1.00 12.02 ? 903 VAL A C 1 ATOM 7411 O O . VAL A 1 903 ? 33.028 45.512 -27.616 1.00 12.53 ? 903 VAL A O 1 ATOM 7412 C CB . VAL A 1 903 ? 33.401 43.518 -29.731 1.00 10.95 ? 903 VAL A CB 1 ATOM 7413 C CG1 . VAL A 1 903 ? 33.044 42.415 -28.745 1.00 13.16 ? 903 VAL A CG1 1 ATOM 7414 C CG2 . VAL A 1 903 ? 33.595 42.935 -31.131 1.00 11.78 ? 903 VAL A CG2 1 ATOM 7415 N N . ARG A 1 904 ? 30.823 45.294 -28.002 1.00 11.32 ? 904 ARG A N 1 ATOM 7416 C CA . ARG A 1 904 ? 30.440 45.876 -26.721 1.00 11.06 ? 904 ARG A CA 1 ATOM 7417 C C . ARG A 1 904 ? 29.894 44.834 -25.791 1.00 11.33 ? 904 ARG A C 1 ATOM 7418 O O . ARG A 1 904 ? 29.524 43.740 -26.220 1.00 10.87 ? 904 ARG A O 1 ATOM 7419 C CB . ARG A 1 904 ? 29.365 46.917 -26.952 1.00 12.04 ? 904 ARG A CB 1 ATOM 7420 C CG . ARG A 1 904 ? 29.925 48.161 -27.623 1.00 13.98 ? 904 ARG A CG 1 ATOM 7421 C CD . ARG A 1 904 ? 28.907 49.244 -27.909 1.00 15.89 ? 904 ARG A CD 1 ATOM 7422 N NE . ARG A 1 904 ? 28.122 48.903 -29.093 1.00 14.10 ? 904 ARG A NE 1 ATOM 7423 C CZ . ARG A 1 904 ? 27.183 49.696 -29.602 1.00 17.12 ? 904 ARG A CZ 1 ATOM 7424 N NH1 . ARG A 1 904 ? 26.897 50.861 -29.018 1.00 16.70 ? 904 ARG A NH1 1 ATOM 7425 N NH2 . ARG A 1 904 ? 26.526 49.301 -30.687 1.00 18.31 ? 904 ARG A NH2 1 ATOM 7426 N N . PRO A 1 905 ? 29.857 45.145 -24.503 1.00 9.71 ? 905 PRO A N 1 ATOM 7427 C CA . PRO A 1 905 ? 29.229 44.230 -23.542 1.00 10.03 ? 905 PRO A CA 1 ATOM 7428 C C . PRO A 1 905 ? 27.766 44.008 -23.884 1.00 10.15 ? 905 PRO A C 1 ATOM 7429 O O . PRO A 1 905 ? 27.150 44.841 -24.549 1.00 11.17 ? 905 PRO A O 1 ATOM 7430 C CB . PRO A 1 905 ? 29.359 44.979 -22.209 1.00 9.99 ? 905 PRO A CB 1 ATOM 7431 C CG . PRO A 1 905 ? 30.551 45.920 -22.413 1.00 10.31 ? 905 PRO A CG 1 ATOM 7432 C CD . PRO A 1 905 ? 30.427 46.353 -23.856 1.00 10.15 ? 905 PRO A CD 1 ATOM 7433 N N . SER A 1 906 ? 27.221 42.882 -23.431 1.00 11.07 ? 906 SER A N 1 ATOM 7434 C CA . SER A 1 906 ? 25.804 42.644 -23.618 1.00 13.80 ? 906 SER A CA 1 ATOM 7435 C C . SER A 1 906 ? 24.954 43.607 -22.794 1.00 14.30 ? 906 SER A C 1 ATOM 7436 O O . SER A 1 906 ? 25.462 44.311 -21.912 1.00 13.74 ? 906 SER A O 1 ATOM 7437 C CB . SER A 1 906 ? 25.500 41.220 -23.231 1.00 16.02 ? 906 SER A CB 1 ATOM 7438 O OG . SER A 1 906 ? 25.290 41.169 -21.851 1.00 19.90 ? 906 SER A OG 1 ATOM 7439 N N . LYS A 1 907 ? 23.651 43.638 -23.065 1.00 15.18 ? 907 LYS A N 1 ATOM 7440 C CA . LYS A 1 907 ? 22.760 44.604 -22.420 1.00 17.37 ? 907 LYS A CA 1 ATOM 7441 C C . LYS A 1 907 ? 22.719 44.470 -20.887 1.00 15.90 ? 907 LYS A C 1 ATOM 7442 O O . LYS A 1 907 ? 22.442 45.434 -20.165 1.00 17.84 ? 907 LYS A O 1 ATOM 7443 C CB . LYS A 1 907 ? 21.351 44.504 -23.037 1.00 18.33 ? 907 LYS A CB 1 ATOM 7444 C CG . LYS A 1 907 ? 21.304 45.036 -24.480 1.00 21.11 ? 907 LYS A CG 1 ATOM 7445 C CD . LYS A 1 907 ? 19.889 45.033 -25.123 1.00 21.86 ? 907 LYS A CD 1 ATOM 7446 C CE . LYS A 1 907 ? 18.746 44.873 -24.115 1.00 27.51 ? 907 LYS A CE 1 ATOM 7447 N NZ . LYS A 1 907 ? 18.450 46.096 -23.300 1.00 29.96 ? 907 LYS A NZ 1 ATOM 7448 N N . LEU A 1 908 ? 23.024 43.287 -20.380 1.00 14.91 ? 908 LEU A N 1 ATOM 7449 C CA . LEU A 1 908 ? 22.968 43.087 -18.928 1.00 15.39 ? 908 LEU A CA 1 ATOM 7450 C C . LEU A 1 908 ? 24.293 43.375 -18.220 1.00 13.66 ? 908 LEU A C 1 ATOM 7451 O O . LEU A 1 908 ? 24.366 43.326 -17.000 1.00 14.68 ? 908 LEU A O 1 ATOM 7452 C CB . LEU A 1 908 ? 22.474 41.672 -18.581 1.00 16.96 ? 908 LEU A CB 1 ATOM 7453 C CG . LEU A 1 908 ? 21.009 41.402 -18.974 1.00 19.28 ? 908 LEU A CG 1 ATOM 7454 C CD1 . LEU A 1 908 ? 20.662 39.947 -18.744 1.00 21.58 ? 908 LEU A CD1 1 ATOM 7455 C CD2 . LEU A 1 908 ? 20.007 42.317 -18.255 1.00 23.41 ? 908 LEU A CD2 1 ATOM 7456 N N . HIS A 1 909 ? 25.350 43.681 -18.973 1.00 11.52 ? 909 HIS A N 1 ATOM 7457 C CA . HIS A 1 909 ? 26.645 43.974 -18.356 1.00 9.90 ? 909 HIS A CA 1 ATOM 7458 C C . HIS A 1 909 ? 26.636 45.356 -17.676 1.00 9.30 ? 909 HIS A C 1 ATOM 7459 O O . HIS A 1 909 ? 26.124 46.322 -18.252 1.00 9.85 ? 909 HIS A O 1 ATOM 7460 C CB . HIS A 1 909 ? 27.733 43.935 -19.402 1.00 9.15 ? 909 HIS A CB 1 ATOM 7461 C CG . HIS A 1 909 ? 29.086 43.672 -18.847 1.00 10.05 ? 909 HIS A CG 1 ATOM 7462 N ND1 . HIS A 1 909 ? 29.788 44.633 -18.139 1.00 11.38 ? 909 HIS A ND1 1 ATOM 7463 C CD2 . HIS A 1 909 ? 29.884 42.579 -18.906 1.00 9.53 ? 909 HIS A CD2 1 ATOM 7464 C CE1 . HIS A 1 909 ? 30.957 44.130 -17.783 1.00 11.58 ? 909 HIS A CE1 1 ATOM 7465 N NE2 . HIS A 1 909 ? 31.054 42.898 -18.266 1.00 11.60 ? 909 HIS A NE2 1 ATOM 7466 N N . PRO A 1 910 ? 27.162 45.463 -16.461 1.00 7.96 ? 910 PRO A N 1 ATOM 7467 C CA . PRO A 1 910 ? 27.140 46.762 -15.763 1.00 7.93 ? 910 PRO A CA 1 ATOM 7468 C C . PRO A 1 910 ? 28.219 47.773 -16.167 1.00 6.89 ? 910 PRO A C 1 ATOM 7469 O O . PRO A 1 910 ? 28.161 48.893 -15.632 1.00 7.03 ? 910 PRO A O 1 ATOM 7470 C CB . PRO A 1 910 ? 27.273 46.382 -14.276 1.00 10.02 ? 910 PRO A CB 1 ATOM 7471 C CG . PRO A 1 910 ? 27.680 44.994 -14.234 1.00 11.42 ? 910 PRO A CG 1 ATOM 7472 C CD . PRO A 1 910 ? 27.599 44.347 -15.583 1.00 8.98 ? 910 PRO A CD 1 ATOM 7473 N N . ALA A 1 911 ? 29.153 47.391 -17.021 1.00 7.11 ? 911 ALA A N 1 ATOM 7474 C CA . ALA A 1 911 ? 30.247 48.282 -17.406 1.00 7.21 ? 911 ALA A CA 1 ATOM 7475 C C . ALA A 1 911 ? 30.133 48.775 -18.821 1.00 7.74 ? 911 ALA A C 1 ATOM 7476 O O . ALA A 1 911 ? 29.402 48.204 -19.653 1.00 8.04 ? 911 ALA A O 1 ATOM 7477 C CB . ALA A 1 911 ? 31.581 47.575 -17.241 1.00 8.01 ? 911 ALA A CB 1 ATOM 7478 N N . GLY A 1 912 ? 30.878 49.824 -19.106 1.00 7.17 ? 912 GLY A N 1 ATOM 7479 C CA . GLY A 1 912 ? 31.155 50.237 -20.463 1.00 7.46 ? 912 GLY A CA 1 ATOM 7480 C C . GLY A 1 912 ? 32.609 50.554 -20.600 1.00 6.30 ? 912 GLY A C 1 ATOM 7481 O O . GLY A 1 912 ? 33.319 50.677 -19.602 1.00 7.07 ? 912 GLY A O 1 ATOM 7482 N N . TYR A 1 913 ? 33.055 50.735 -21.833 1.00 6.32 ? 913 TYR A N 1 ATOM 7483 C CA . TYR A 1 913 ? 34.463 50.908 -22.125 1.00 6.46 ? 913 TYR A CA 1 ATOM 7484 C C . TYR A 1 913 ? 34.652 51.961 -23.191 1.00 6.69 ? 913 TYR A C 1 ATOM 7485 O O . TYR A 1 913 ? 33.859 52.021 -24.152 1.00 8.24 ? 913 TYR A O 1 ATOM 7486 C CB . TYR A 1 913 ? 35.153 49.592 -22.585 1.00 7.43 ? 913 TYR A CB 1 ATOM 7487 C CG . TYR A 1 913 ? 35.067 48.551 -21.489 1.00 7.07 ? 913 TYR A CG 1 ATOM 7488 C CD1 . TYR A 1 913 ? 35.946 48.610 -20.409 1.00 7.91 ? 913 TYR A CD1 1 ATOM 7489 C CD2 . TYR A 1 913 ? 34.085 47.575 -21.493 1.00 6.74 ? 913 TYR A CD2 1 ATOM 7490 C CE1 . TYR A 1 913 ? 35.863 47.726 -19.379 1.00 6.88 ? 913 TYR A CE1 1 ATOM 7491 C CE2 . TYR A 1 913 ? 34.009 46.653 -20.435 1.00 7.49 ? 913 TYR A CE2 1 ATOM 7492 C CZ . TYR A 1 913 ? 34.903 46.756 -19.391 1.00 8.52 ? 913 TYR A CZ 1 ATOM 7493 O OH . TYR A 1 913 ? 34.785 45.871 -18.343 1.00 9.77 ? 913 TYR A OH 1 ATOM 7494 N N . LEU A 1 914 ? 35.744 52.701 -23.081 1.00 7.25 ? 914 LEU A N 1 ATOM 7495 C CA . LEU A 1 914 ? 36.058 53.719 -24.069 1.00 6.96 ? 914 LEU A CA 1 ATOM 7496 C C . LEU A 1 914 ? 36.629 53.114 -25.341 1.00 8.07 ? 914 LEU A C 1 ATOM 7497 O O . LEU A 1 914 ? 37.188 52.026 -25.329 1.00 8.89 ? 914 LEU A O 1 ATOM 7498 C CB . LEU A 1 914 ? 37.090 54.695 -23.505 1.00 6.65 ? 914 LEU A CB 1 ATOM 7499 C CG . LEU A 1 914 ? 36.619 55.594 -22.360 1.00 7.53 ? 914 LEU A CG 1 ATOM 7500 C CD1 . LEU A 1 914 ? 37.742 56.596 -22.053 1.00 8.72 ? 914 LEU A CD1 1 ATOM 7501 C CD2 . LEU A 1 914 ? 35.312 56.321 -22.710 1.00 8.24 ? 914 LEU A CD2 1 ATOM 7502 N N . THR A 1 915 ? 36.505 53.865 -26.440 1.00 8.93 ? 915 THR A N 1 ATOM 7503 C CA . THR A 1 915 ? 37.279 53.587 -27.633 1.00 9.55 ? 915 THR A CA 1 ATOM 7504 C C . THR A 1 915 ? 38.698 54.141 -27.504 1.00 9.85 ? 915 THR A C 1 ATOM 7505 O O . THR A 1 915 ? 38.962 54.999 -26.646 1.00 8.76 ? 915 THR A O 1 ATOM 7506 C CB . THR A 1 915 ? 36.672 54.280 -28.824 1.00 10.86 ? 915 THR A CB 1 ATOM 7507 O OG1 . THR A 1 915 ? 36.591 55.703 -28.541 1.00 12.81 ? 915 THR A OG1 1 ATOM 7508 C CG2 . THR A 1 915 ? 35.264 53.789 -29.082 1.00 13.30 ? 915 THR A CG2 1 ATOM 7509 N N . SER A 1 916 ? 39.600 53.743 -28.385 1.00 9.89 ? 916 SER A N 1 ATOM 7510 C CA . SER A 1 916 ? 40.942 54.284 -28.417 1.00 10.66 ? 916 SER A CA 1 ATOM 7511 C C . SER A 1 916 ? 40.921 55.798 -28.511 1.00 9.57 ? 916 SER A C 1 ATOM 7512 O O . SER A 1 916 ? 41.627 56.460 -27.772 1.00 9.90 ? 916 SER A O 1 ATOM 7513 C CB . SER A 1 916 ? 41.701 53.721 -29.634 1.00 12.19 ? 916 SER A CB 1 ATOM 7514 O OG . SER A 1 916 ? 42.878 54.455 -29.895 1.00 18.99 ? 916 SER A OG 1 ATOM 7515 N N . ALA A 1 917 ? 40.107 56.368 -29.399 1.00 8.99 ? 917 ALA A N 1 ATOM 7516 C CA . ALA A 1 917 ? 40.179 57.829 -29.573 1.00 9.30 ? 917 ALA A CA 1 ATOM 7517 C C . ALA A 1 917 ? 39.701 58.543 -28.321 1.00 8.72 ? 917 ALA A C 1 ATOM 7518 O O . ALA A 1 917 ? 40.250 59.589 -27.954 1.00 8.89 ? 917 ALA A O 1 ATOM 7519 C CB . ALA A 1 917 ? 39.369 58.287 -30.772 1.00 10.82 ? 917 ALA A CB 1 ATOM 7520 N N . ALA A 1 918 ? 38.700 57.991 -27.629 1.00 7.79 ? 918 ALA A N 1 ATOM 7521 C CA . ALA A 1 918 ? 38.222 58.653 -26.403 1.00 7.48 ? 918 ALA A CA 1 ATOM 7522 C C . ALA A 1 918 ? 39.234 58.523 -25.279 1.00 7.12 ? 918 ALA A C 1 ATOM 7523 O O . ALA A 1 918 ? 39.430 59.456 -24.503 1.00 6.93 ? 918 ALA A O 1 ATOM 7524 C CB . ALA A 1 918 ? 36.851 58.134 -25.984 1.00 7.68 ? 918 ALA A CB 1 ATOM 7525 N N . HIS A 1 919 ? 39.864 57.366 -25.154 1.00 6.78 ? 919 HIS A N 1 ATOM 7526 C CA . HIS A 1 919 ? 40.897 57.224 -24.135 1.00 6.80 ? 919 HIS A CA 1 ATOM 7527 C C . HIS A 1 919 ? 42.054 58.179 -24.415 1.00 6.34 ? 919 HIS A C 1 ATOM 7528 O O . HIS A 1 919 ? 42.568 58.831 -23.487 1.00 7.80 ? 919 HIS A O 1 ATOM 7529 C CB . HIS A 1 919 ? 41.344 55.746 -24.107 1.00 8.48 ? 919 HIS A CB 1 ATOM 7530 C CG . HIS A 1 919 ? 42.537 55.480 -23.248 1.00 8.64 ? 919 HIS A CG 1 ATOM 7531 N ND1 . HIS A 1 919 ? 42.514 55.588 -21.875 1.00 13.51 ? 919 HIS A ND1 1 ATOM 7532 C CD2 . HIS A 1 919 ? 43.796 55.114 -23.582 1.00 10.31 ? 919 HIS A CD2 1 ATOM 7533 C CE1 . HIS A 1 919 ? 43.716 55.278 -21.399 1.00 9.53 ? 919 HIS A CE1 1 ATOM 7534 N NE2 . HIS A 1 919 ? 44.502 54.987 -22.411 1.00 13.75 ? 919 HIS A NE2 1 ATOM 7535 N N . LYS A 1 920 ? 42.510 58.267 -25.669 1.00 7.06 ? 920 LYS A N 1 ATOM 7536 C CA . LYS A 1 920 ? 43.589 59.195 -25.982 1.00 7.63 ? 920 LYS A CA 1 ATOM 7537 C C . LYS A 1 920 ? 43.164 60.627 -25.688 1.00 6.62 ? 920 LYS A C 1 ATOM 7538 O O . LYS A 1 920 ? 43.962 61.430 -25.204 1.00 6.74 ? 920 LYS A O 1 ATOM 7539 C CB . LYS A 1 920 ? 44.082 59.030 -27.421 1.00 9.15 ? 920 LYS A CB 1 ATOM 7540 C CG . LYS A 1 920 ? 44.944 57.786 -27.523 1.00 13.33 ? 920 LYS A CG 1 ATOM 7541 C CD . LYS A 1 920 ? 45.746 57.749 -28.790 1.00 16.50 ? 920 LYS A CD 1 ATOM 7542 C CE . LYS A 1 920 ? 46.617 56.503 -28.819 1.00 16.94 ? 920 LYS A CE 1 ATOM 7543 N NZ . LYS A 1 920 ? 47.875 56.609 -27.981 1.00 18.12 ? 920 LYS A NZ 1 ATOM 7544 N N . ALA A 1 921 ? 41.907 60.939 -25.982 1.00 6.68 ? 921 ALA A N 1 ATOM 7545 C CA . ALA A 1 921 ? 41.424 62.286 -25.673 1.00 6.93 ? 921 ALA A CA 1 ATOM 7546 C C . ALA A 1 921 ? 41.464 62.553 -24.167 1.00 6.94 ? 921 ALA A C 1 ATOM 7547 O O . ALA A 1 921 ? 41.832 63.652 -23.711 1.00 6.92 ? 921 ALA A O 1 ATOM 7548 C CB . ALA A 1 921 ? 39.993 62.467 -26.213 1.00 6.63 ? 921 ALA A CB 1 ATOM 7549 N N . SER A 1 922 ? 41.078 61.548 -23.388 1.00 5.71 ? 922 SER A N 1 ATOM 7550 C CA . SER A 1 922 ? 41.157 61.736 -21.933 1.00 5.63 ? 922 SER A CA 1 ATOM 7551 C C . SER A 1 922 ? 42.621 61.977 -21.499 1.00 5.82 ? 922 SER A C 1 ATOM 7552 O O . SER A 1 922 ? 42.925 62.851 -20.683 1.00 5.93 ? 922 SER A O 1 ATOM 7553 C CB . SER A 1 922 ? 40.591 60.517 -21.213 1.00 6.57 ? 922 SER A CB 1 ATOM 7554 O OG . SER A 1 922 ? 40.745 60.673 -19.804 1.00 7.15 ? 922 SER A OG 1 ATOM 7555 N N . GLN A 1 923 ? 43.543 61.213 -22.052 1.00 6.33 ? 923 GLN A N 1 ATOM 7556 C CA . GLN A 1 923 ? 44.960 61.394 -21.737 1.00 7.09 ? 923 GLN A CA 1 ATOM 7557 C C . GLN A 1 923 ? 45.437 62.791 -22.146 1.00 7.13 ? 923 GLN A C 1 ATOM 7558 O O . GLN A 1 923 ? 46.287 63.374 -21.461 1.00 8.18 ? 923 GLN A O 1 ATOM 7559 C CB . GLN A 1 923 ? 45.836 60.303 -22.376 1.00 7.27 ? 923 GLN A CB 1 ATOM 7560 C CG . GLN A 1 923 ? 45.543 58.939 -21.849 1.00 6.57 ? 923 GLN A CG 1 ATOM 7561 C CD . GLN A 1 923 ? 46.448 57.897 -22.464 1.00 9.29 ? 923 GLN A CD 1 ATOM 7562 O OE1 . GLN A 1 923 ? 46.557 57.850 -23.696 1.00 10.22 ? 923 GLN A OE1 1 ATOM 7563 N NE2 . GLN A 1 923 ? 47.076 57.046 -21.623 1.00 9.69 ? 923 GLN A NE2 1 ATOM 7564 N N . SER A 1 924 ? 44.912 63.360 -23.238 1.00 7.06 ? 924 SER A N 1 ATOM 7565 C CA . SER A 1 924 ? 45.344 64.698 -23.668 1.00 8.32 ? 924 SER A CA 1 ATOM 7566 C C . SER A 1 924 ? 44.934 65.740 -22.646 1.00 8.79 ? 924 SER A C 1 ATOM 7567 O O . SER A 1 924 ? 45.527 66.833 -22.560 1.00 9.11 ? 924 SER A O 1 ATOM 7568 C CB . SER A 1 924 ? 44.722 65.042 -25.029 1.00 9.18 ? 924 SER A CB 1 ATOM 7569 O OG . SER A 1 924 ? 43.351 65.424 -24.928 1.00 9.77 ? 924 SER A OG 1 ATOM 7570 N N . LEU A 1 925 ? 43.853 65.462 -21.921 1.00 7.47 ? 925 LEU A N 1 ATOM 7571 C CA . LEU A 1 925 ? 43.380 66.384 -20.881 1.00 6.65 ? 925 LEU A CA 1 ATOM 7572 C C . LEU A 1 925 ? 44.108 66.199 -19.558 1.00 7.52 ? 925 LEU A C 1 ATOM 7573 O O . LEU A 1 925 ? 44.472 67.184 -18.906 1.00 9.17 ? 925 LEU A O 1 ATOM 7574 C CB . LEU A 1 925 ? 41.864 66.222 -20.608 1.00 6.36 ? 925 LEU A CB 1 ATOM 7575 C CG . LEU A 1 925 ? 40.982 66.497 -21.824 1.00 7.47 ? 925 LEU A CG 1 ATOM 7576 C CD1 . LEU A 1 925 ? 39.548 66.142 -21.473 1.00 8.23 ? 925 LEU A CD1 1 ATOM 7577 C CD2 . LEU A 1 925 ? 41.123 67.963 -22.264 1.00 10.51 ? 925 LEU A CD2 1 ATOM 7578 N N . LEU A 1 926 ? 44.297 64.960 -19.140 1.00 7.21 ? 926 LEU A N 1 ATOM 7579 C CA . LEU A 1 926 ? 44.848 64.710 -17.823 1.00 7.93 ? 926 LEU A CA 1 ATOM 7580 C C . LEU A 1 926 ? 46.353 64.691 -17.802 1.00 8.03 ? 926 LEU A C 1 ATOM 7581 O O . LEU A 1 926 ? 46.926 65.111 -16.781 1.00 8.54 ? 926 LEU A O 1 ATOM 7582 C CB . LEU A 1 926 ? 44.277 63.428 -17.249 1.00 8.50 ? 926 LEU A CB 1 ATOM 7583 C CG . LEU A 1 926 ? 42.768 63.544 -16.981 1.00 10.96 ? 926 LEU A CG 1 ATOM 7584 C CD1 . LEU A 1 926 ? 42.281 62.190 -16.454 1.00 14.29 ? 926 LEU A CD1 1 ATOM 7585 C CD2 . LEU A 1 926 ? 42.444 64.680 -16.013 1.00 12.50 ? 926 LEU A CD2 1 ATOM 7586 N N . ASP A 1 927 ? 46.989 64.212 -18.870 1.00 7.06 ? 927 ASP A N 1 ATOM 7587 C CA . ASP A 1 927 ? 48.458 64.153 -18.886 1.00 7.30 ? 927 ASP A CA 1 ATOM 7588 C C . ASP A 1 927 ? 48.977 64.715 -20.199 1.00 6.99 ? 927 ASP A C 1 ATOM 7589 O O . ASP A 1 927 ? 49.548 63.982 -20.998 1.00 7.33 ? 927 ASP A O 1 ATOM 7590 C CB . ASP A 1 927 ? 48.972 62.735 -18.631 1.00 8.87 ? 927 ASP A CB 1 ATOM 7591 C CG . ASP A 1 927 ? 48.636 62.256 -17.198 1.00 11.08 ? 927 ASP A CG 1 ATOM 7592 O OD1 . ASP A 1 927 ? 49.315 62.673 -16.181 1.00 10.20 ? 927 ASP A OD1 1 ATOM 7593 O OD2 . ASP A 1 927 ? 47.660 61.490 -17.018 1.00 12.53 ? 927 ASP A OD2 1 ATOM 7594 N N . PRO A 1 928 ? 48.836 66.025 -20.383 1.00 7.29 ? 928 PRO A N 1 ATOM 7595 C CA . PRO A 1 928 ? 49.332 66.692 -21.597 1.00 7.47 ? 928 PRO A CA 1 ATOM 7596 C C . PRO A 1 928 ? 50.852 66.677 -21.615 1.00 7.79 ? 928 PRO A C 1 ATOM 7597 O O . PRO A 1 928 ? 51.496 66.419 -20.593 1.00 8.27 ? 928 PRO A O 1 ATOM 7598 C CB . PRO A 1 928 ? 48.814 68.129 -21.432 1.00 8.91 ? 928 PRO A CB 1 ATOM 7599 C CG . PRO A 1 928 ? 48.708 68.314 -20.012 1.00 10.53 ? 928 PRO A CG 1 ATOM 7600 C CD . PRO A 1 928 ? 48.265 66.976 -19.410 1.00 8.99 ? 928 PRO A CD 1 ATOM 7601 N N . LEU A 1 929 ? 51.448 66.991 -22.763 1.00 7.54 ? 929 LEU A N 1 ATOM 7602 C CA . LEU A 1 929 ? 52.872 67.316 -22.750 1.00 8.25 ? 929 LEU A CA 1 ATOM 7603 C C . LEU A 1 929 ? 53.142 68.473 -21.818 1.00 8.34 ? 929 LEU A C 1 ATOM 7604 O O . LEU A 1 929 ? 52.335 69.393 -21.725 1.00 9.92 ? 929 LEU A O 1 ATOM 7605 C CB . LEU A 1 929 ? 53.342 67.707 -24.155 1.00 8.38 ? 929 LEU A CB 1 ATOM 7606 C CG . LEU A 1 929 ? 53.234 66.661 -25.249 1.00 8.77 ? 929 LEU A CG 1 ATOM 7607 C CD1 . LEU A 1 929 ? 53.792 67.232 -26.575 1.00 8.97 ? 929 LEU A CD1 1 ATOM 7608 C CD2 . LEU A 1 929 ? 53.964 65.361 -24.848 1.00 8.60 ? 929 LEU A CD2 1 ATOM 7609 N N . ASP A 1 930 ? 54.250 68.416 -21.101 1.00 7.29 ? 930 ASP A N 1 ATOM 7610 C CA . ASP A 1 930 ? 54.758 69.541 -20.323 1.00 7.45 ? 930 ASP A CA 1 ATOM 7611 C C . ASP A 1 930 ? 55.685 70.389 -21.178 1.00 8.14 ? 930 ASP A C 1 ATOM 7612 O O . ASP A 1 930 ? 56.406 69.865 -21.957 1.00 8.35 ? 930 ASP A O 1 ATOM 7613 C CB . ASP A 1 930 ? 55.493 69.018 -19.089 1.00 7.46 ? 930 ASP A CB 1 ATOM 7614 C CG . ASP A 1 930 ? 54.703 67.956 -18.378 1.00 11.18 ? 930 ASP A CG 1 ATOM 7615 O OD1 . ASP A 1 930 ? 53.642 68.334 -17.893 1.00 14.02 ? 930 ASP A OD1 1 ATOM 7616 O OD2 . ASP A 1 930 ? 55.100 66.776 -18.346 1.00 11.09 ? 930 ASP A OD2 1 ATOM 7617 N N . LYS A 1 931 ? 55.640 71.694 -20.996 1.00 7.96 ? 931 LYS A N 1 ATOM 7618 C CA . LYS A 1 931 ? 56.401 72.629 -21.828 1.00 8.02 ? 931 LYS A CA 1 ATOM 7619 C C . LYS A 1 931 ? 57.323 73.425 -20.943 1.00 8.51 ? 931 LYS A C 1 ATOM 7620 O O . LYS A 1 931 ? 56.897 74.025 -19.951 1.00 8.92 ? 931 LYS A O 1 ATOM 7621 C CB . LYS A 1 931 ? 55.432 73.590 -22.546 1.00 8.43 ? 931 LYS A CB 1 ATOM 7622 C CG . LYS A 1 931 ? 54.455 72.968 -23.539 1.00 11.63 ? 931 LYS A CG 1 ATOM 7623 C CD . LYS A 1 931 ? 53.592 74.057 -24.217 1.00 12.36 ? 931 LYS A CD 1 ATOM 7624 C CE . LYS A 1 931 ? 52.626 74.734 -23.247 1.00 17.34 ? 931 LYS A CE 1 ATOM 7625 N NZ . LYS A 1 931 ? 51.822 75.818 -23.873 1.00 18.31 ? 931 LYS A NZ 1 ATOM 7626 N N . PHE A 1 932 ? 58.604 73.429 -21.284 1.00 7.32 ? 932 PHE A N 1 ATOM 7627 C CA . PHE A 1 932 ? 59.618 74.153 -20.548 1.00 7.21 ? 932 PHE A CA 1 ATOM 7628 C C . PHE A 1 932 ? 60.277 75.202 -21.459 1.00 7.52 ? 932 PHE A C 1 ATOM 7629 O O . PHE A 1 932 ? 60.599 74.883 -22.608 1.00 8.45 ? 932 PHE A O 1 ATOM 7630 C CB . PHE A 1 932 ? 60.699 73.216 -20.071 1.00 7.64 ? 932 PHE A CB 1 ATOM 7631 C CG . PHE A 1 932 ? 60.214 72.124 -19.162 1.00 7.69 ? 932 PHE A CG 1 ATOM 7632 C CD1 . PHE A 1 932 ? 59.679 70.963 -19.686 1.00 7.64 ? 932 PHE A CD1 1 ATOM 7633 C CD2 . PHE A 1 932 ? 60.314 72.279 -17.777 1.00 9.44 ? 932 PHE A CD2 1 ATOM 7634 C CE1 . PHE A 1 932 ? 59.259 69.905 -18.831 1.00 8.76 ? 932 PHE A CE1 1 ATOM 7635 C CE2 . PHE A 1 932 ? 59.907 71.253 -16.900 1.00 10.67 ? 932 PHE A CE2 1 ATOM 7636 C CZ . PHE A 1 932 ? 59.366 70.085 -17.422 1.00 9.71 ? 932 PHE A CZ 1 ATOM 7637 N N . ILE A 1 933 ? 60.525 76.392 -20.916 1.00 7.07 ? 933 ILE A N 1 ATOM 7638 C CA . ILE A 1 933 ? 61.195 77.442 -21.687 1.00 7.13 ? 933 ILE A CA 1 ATOM 7639 C C . ILE A 1 933 ? 62.529 77.668 -21.029 1.00 7.83 ? 933 ILE A C 1 ATOM 7640 O O . ILE A 1 933 ? 62.586 77.949 -19.836 1.00 8.10 ? 933 ILE A O 1 ATOM 7641 C CB . ILE A 1 933 ? 60.385 78.740 -21.682 1.00 7.15 ? 933 ILE A CB 1 ATOM 7642 C CG1 . ILE A 1 933 ? 58.982 78.524 -22.215 1.00 7.59 ? 933 ILE A CG1 1 ATOM 7643 C CG2 . ILE A 1 933 ? 61.101 79.837 -22.497 1.00 8.74 ? 933 ILE A CG2 1 ATOM 7644 C CD1 . ILE A 1 933 ? 58.057 79.730 -22.010 1.00 9.46 ? 933 ILE A CD1 1 ATOM 7645 N N . PHE A 1 934 ? 63.628 77.539 -21.786 1.00 7.83 ? 934 PHE A N 1 ATOM 7646 C CA . PHE A 1 934 ? 64.945 77.778 -21.204 1.00 9.37 ? 934 PHE A CA 1 ATOM 7647 C C . PHE A 1 934 ? 65.071 79.237 -20.723 1.00 9.75 ? 934 PHE A C 1 ATOM 7648 O O . PHE A 1 934 ? 64.710 80.169 -21.447 1.00 10.02 ? 934 PHE A O 1 ATOM 7649 C CB . PHE A 1 934 ? 66.071 77.407 -22.174 1.00 9.74 ? 934 PHE A CB 1 ATOM 7650 C CG . PHE A 1 934 ? 67.416 77.472 -21.545 1.00 9.93 ? 934 PHE A CG 1 ATOM 7651 C CD1 . PHE A 1 934 ? 67.825 76.503 -20.636 1.00 10.73 ? 934 PHE A CD1 1 ATOM 7652 C CD2 . PHE A 1 934 ? 68.257 78.566 -21.787 1.00 12.53 ? 934 PHE A CD2 1 ATOM 7653 C CE1 . PHE A 1 934 ? 69.078 76.585 -20.016 1.00 15.47 ? 934 PHE A CE1 1 ATOM 7654 C CE2 . PHE A 1 934 ? 69.489 78.664 -21.178 1.00 15.04 ? 934 PHE A CE2 1 ATOM 7655 C CZ . PHE A 1 934 ? 69.912 77.689 -20.283 1.00 14.84 ? 934 PHE A CZ 1 ATOM 7656 N N . ALA A 1 935 ? 65.540 79.427 -19.489 1.00 10.52 ? 935 ALA A N 1 ATOM 7657 C CA . ALA A 1 935 ? 65.414 80.741 -18.861 1.00 13.39 ? 935 ALA A CA 1 ATOM 7658 C C . ALA A 1 935 ? 66.498 81.725 -19.259 1.00 16.06 ? 935 ALA A C 1 ATOM 7659 O O . ALA A 1 935 ? 66.249 82.943 -19.267 1.00 19.19 ? 935 ALA A O 1 ATOM 7660 C CB . ALA A 1 935 ? 65.377 80.609 -17.352 1.00 14.99 ? 935 ALA A CB 1 ATOM 7661 N N . GLU A 1 936 ? 67.684 81.228 -19.572 1.00 16.32 ? 936 GLU A N 1 ATOM 7662 C CA . GLU A 1 936 ? 68.796 82.137 -19.841 1.00 17.41 ? 936 GLU A CA 1 ATOM 7663 C C . GLU A 1 936 ? 69.047 82.254 -21.336 1.00 16.50 ? 936 GLU A C 1 ATOM 7664 O O . GLU A 1 936 ? 68.336 81.672 -22.148 1.00 16.38 ? 936 GLU A O 1 ATOM 7665 C CB . GLU A 1 936 ? 70.042 81.729 -19.054 1.00 19.22 ? 936 GLU A CB 1 ATOM 7666 C CG . GLU A 1 936 ? 69.866 81.920 -17.550 1.00 24.17 ? 936 GLU A CG 1 ATOM 7667 C CD . GLU A 1 936 ? 69.479 83.346 -17.153 1.00 31.40 ? 936 GLU A CD 1 ATOM 7668 O OE1 . GLU A 1 936 ? 69.984 84.316 -17.777 1.00 34.60 ? 936 GLU A OE1 1 ATOM 7669 O OE2 . GLU A 1 936 ? 68.665 83.512 -16.206 1.00 34.95 ? 936 GLU A OE2 1 ATOM 7670 N N . ASN A 1 937 ? 70.066 83.012 -21.720 1.00 16.25 ? 937 ASN A N 1 ATOM 7671 C CA . ASN A 1 937 ? 70.203 83.266 -23.142 1.00 15.98 ? 937 ASN A CA 1 ATOM 7672 C C . ASN A 1 937 ? 70.746 82.102 -23.953 1.00 15.00 ? 937 ASN A C 1 ATOM 7673 O O . ASN A 1 937 ? 70.339 81.906 -25.088 1.00 15.67 ? 937 ASN A O 1 ATOM 7674 C CB . ASN A 1 937 ? 71.085 84.489 -23.368 1.00 15.33 ? 937 ASN A CB 1 ATOM 7675 C CG . ASN A 1 937 ? 70.359 85.790 -23.071 1.00 18.13 ? 937 ASN A CG 1 ATOM 7676 O OD1 . ASN A 1 937 ? 69.128 85.826 -22.959 1.00 19.43 ? 937 ASN A OD1 1 ATOM 7677 N ND2 . ASN A 1 937 ? 71.119 86.876 -22.970 1.00 20.64 ? 937 ASN A ND2 1 ATOM 7678 N N . GLU A 1 938 ? 71.685 81.352 -23.373 1.00 15.87 ? 938 GLU A N 1 ATOM 7679 C CA . GLU A 1 938 ? 72.325 80.266 -24.084 1.00 16.32 ? 938 GLU A CA 1 ATOM 7680 C C . GLU A 1 938 ? 72.406 79.040 -23.200 1.00 15.31 ? 938 GLU A C 1 ATOM 7681 O O . GLU A 1 938 ? 72.805 79.132 -22.050 1.00 16.31 ? 938 GLU A O 1 ATOM 7682 C CB . GLU A 1 938 ? 73.741 80.640 -24.548 1.00 17.71 ? 938 GLU A CB 1 ATOM 7683 C CG . GLU A 1 938 ? 74.435 79.440 -25.170 1.00 22.45 ? 938 GLU A CG 1 ATOM 7684 C CD . GLU A 1 938 ? 75.721 79.761 -25.902 1.00 29.58 ? 938 GLU A CD 1 ATOM 7685 O OE1 . GLU A 1 938 ? 76.409 80.753 -25.543 1.00 31.90 ? 938 GLU A OE1 1 ATOM 7686 O OE2 . GLU A 1 938 ? 76.045 78.989 -26.842 1.00 32.61 ? 938 GLU A OE2 1 ATOM 7687 N N . TRP A 1 939 ? 72.046 77.899 -23.774 1.00 16.20 ? 939 TRP A N 1 ATOM 7688 C CA . TRP A 1 939 ? 72.123 76.631 -23.070 1.00 15.98 ? 939 TRP A CA 1 ATOM 7689 C C . TRP A 1 939 ? 73.314 75.852 -23.622 1.00 16.67 ? 939 TRP A C 1 ATOM 7690 O O . TRP A 1 939 ? 73.223 75.236 -24.682 1.00 18.06 ? 939 TRP A O 1 ATOM 7691 C CB . TRP A 1 939 ? 70.803 75.898 -23.289 1.00 14.54 ? 939 TRP A CB 1 ATOM 7692 C CG . TRP A 1 939 ? 70.668 74.545 -22.663 1.00 12.03 ? 939 TRP A CG 1 ATOM 7693 C CD1 . TRP A 1 939 ? 71.518 73.920 -21.797 1.00 13.94 ? 939 TRP A CD1 1 ATOM 7694 C CD2 . TRP A 1 939 ? 69.565 73.658 -22.866 1.00 10.94 ? 939 TRP A CD2 1 ATOM 7695 N NE1 . TRP A 1 939 ? 71.013 72.686 -21.455 1.00 12.06 ? 939 TRP A NE1 1 ATOM 7696 C CE2 . TRP A 1 939 ? 69.819 72.500 -22.108 1.00 9.89 ? 939 TRP A CE2 1 ATOM 7697 C CE3 . TRP A 1 939 ? 68.386 73.721 -23.635 1.00 11.29 ? 939 TRP A CE3 1 ATOM 7698 C CZ2 . TRP A 1 939 ? 68.934 71.422 -22.075 1.00 11.35 ? 939 TRP A CZ2 1 ATOM 7699 C CZ3 . TRP A 1 939 ? 67.519 72.659 -23.621 1.00 11.78 ? 939 TRP A CZ3 1 ATOM 7700 C CH2 . TRP A 1 939 ? 67.799 71.521 -22.839 1.00 11.30 ? 939 TRP A CH2 1 ATOM 7701 N N . ILE A 1 940 ? 74.435 75.905 -22.895 1.00 18.70 ? 940 ILE A N 1 ATOM 7702 C CA . ILE A 1 940 ? 75.645 75.203 -23.326 1.00 19.30 ? 940 ILE A CA 1 ATOM 7703 C C . ILE A 1 940 ? 75.491 73.703 -23.017 1.00 17.40 ? 940 ILE A C 1 ATOM 7704 O O . ILE A 1 940 ? 75.063 73.340 -21.930 1.00 17.97 ? 940 ILE A O 1 ATOM 7705 C CB . ILE A 1 940 ? 76.899 75.820 -22.669 1.00 20.12 ? 940 ILE A CB 1 ATOM 7706 C CG1 . ILE A 1 940 ? 77.043 77.289 -23.102 1.00 20.97 ? 940 ILE A CG1 1 ATOM 7707 C CG2 . ILE A 1 940 ? 78.164 75.017 -23.026 1.00 21.40 ? 940 ILE A CG2 1 ATOM 7708 C CD1 . ILE A 1 940 ? 78.291 77.985 -22.597 1.00 21.90 ? 940 ILE A CD1 1 ATOM 7709 N N . GLY A 1 941 ? 75.795 72.849 -23.985 1.00 16.97 ? 941 GLY A N 1 ATOM 7710 C CA . GLY A 1 941 ? 75.698 71.408 -23.773 1.00 15.87 ? 941 GLY A CA 1 ATOM 7711 C C . GLY A 1 941 ? 74.314 70.819 -24.053 1.00 15.48 ? 941 GLY A C 1 ATOM 7712 O O . GLY A 1 941 ? 74.087 69.632 -23.802 1.00 13.93 ? 941 GLY A O 1 ATOM 7713 N N . ALA A 1 942 ? 73.409 71.632 -24.600 1.00 14.41 ? 942 ALA A N 1 ATOM 7714 C CA . ALA A 1 942 ? 72.029 71.199 -24.861 1.00 14.23 ? 942 ALA A CA 1 ATOM 7715 C C . ALA A 1 942 ? 71.988 69.982 -25.748 1.00 14.87 ? 942 ALA A C 1 ATOM 7716 O O . ALA A 1 942 ? 72.754 69.901 -26.717 1.00 15.15 ? 942 ALA A O 1 ATOM 7717 C CB . ALA A 1 942 ? 71.218 72.320 -25.504 1.00 14.90 ? 942 ALA A CB 1 ATOM 7718 N N . GLN A 1 943 ? 71.104 69.039 -25.415 1.00 14.46 ? 943 GLN A N 1 ATOM 7719 C CA . GLN A 1 943 ? 70.844 67.881 -26.243 1.00 14.39 ? 943 GLN A CA 1 ATOM 7720 C C . GLN A 1 943 ? 69.416 67.874 -26.787 1.00 12.97 ? 943 GLN A C 1 ATOM 7721 O O . GLN A 1 943 ? 68.527 68.516 -26.205 1.00 14.22 ? 943 GLN A O 1 ATOM 7722 C CB . GLN A 1 943 ? 71.118 66.589 -25.459 1.00 16.01 ? 943 GLN A CB 1 ATOM 7723 C CG . GLN A 1 943 ? 72.494 66.589 -24.810 1.00 20.65 ? 943 GLN A CG 1 ATOM 7724 C CD . GLN A 1 943 ? 72.721 65.365 -23.975 1.00 26.62 ? 943 GLN A CD 1 ATOM 7725 O OE1 . GLN A 1 943 ? 71.780 64.849 -23.356 1.00 29.47 ? 943 GLN A OE1 1 ATOM 7726 N NE2 . GLN A 1 943 ? 73.965 64.894 -23.937 1.00 29.30 ? 943 GLN A NE2 1 ATOM 7727 N N . GLY A 1 944 ? 69.188 67.127 -27.855 1.00 13.41 ? 944 GLY A N 1 ATOM 7728 C CA . GLY A 1 944 ? 67.962 67.209 -28.603 1.00 12.95 ? 944 GLY A CA 1 ATOM 7729 C C . GLY A 1 944 ? 66.836 66.349 -28.089 1.00 13.04 ? 944 GLY A C 1 ATOM 7730 O O . GLY A 1 944 ? 65.645 66.580 -28.367 1.00 12.47 ? 944 GLY A O 1 ATOM 7731 N N . GLN A 1 945 ? 67.198 65.317 -27.355 1.00 11.74 ? 945 GLN A N 1 ATOM 7732 C CA . GLN A 1 945 ? 66.190 64.322 -27.023 1.00 12.90 ? 945 GLN A CA 1 ATOM 7733 C C . GLN A 1 945 ? 66.642 63.488 -25.846 1.00 11.42 ? 945 GLN A C 1 ATOM 7734 O O . GLN A 1 945 ? 67.843 63.326 -25.584 1.00 11.95 ? 945 GLN A O 1 ATOM 7735 C CB . GLN A 1 945 ? 65.989 63.405 -28.232 1.00 12.51 ? 945 GLN A CB 1 ATOM 7736 C CG . GLN A 1 945 ? 64.709 62.588 -28.261 1.00 15.66 ? 945 GLN A CG 1 ATOM 7737 C CD . GLN A 1 945 ? 64.658 61.650 -29.467 1.00 15.93 ? 945 GLN A CD 1 ATOM 7738 O OE1 . GLN A 1 945 ? 63.779 61.767 -30.323 1.00 21.60 ? 945 GLN A OE1 1 ATOM 7739 N NE2 . GLN A 1 945 ? 65.598 60.725 -29.529 1.00 20.70 ? 945 GLN A NE2 1 ATOM 7740 N N . PHE A 1 946 ? 65.650 63.008 -25.100 1.00 9.82 ? 946 PHE A N 1 ATOM 7741 C CA . PHE A 1 946 ? 65.876 61.978 -24.089 1.00 8.77 ? 946 PHE A CA 1 ATOM 7742 C C . PHE A 1 946 ? 64.804 60.945 -24.238 1.00 8.38 ? 946 PHE A C 1 ATOM 7743 O O . PHE A 1 946 ? 63.652 61.273 -24.446 1.00 8.00 ? 946 PHE A O 1 ATOM 7744 C CB . PHE A 1 946 ? 65.855 62.567 -22.681 1.00 8.18 ? 946 PHE A CB 1 ATOM 7745 C CG . PHE A 1 946 ? 65.759 61.526 -21.597 1.00 8.65 ? 946 PHE A CG 1 ATOM 7746 C CD1 . PHE A 1 946 ? 66.844 60.719 -21.286 1.00 9.76 ? 946 PHE A CD1 1 ATOM 7747 C CD2 . PHE A 1 946 ? 64.569 61.357 -20.898 1.00 9.92 ? 946 PHE A CD2 1 ATOM 7748 C CE1 . PHE A 1 946 ? 66.713 59.730 -20.284 1.00 10.19 ? 946 PHE A CE1 1 ATOM 7749 C CE2 . PHE A 1 946 ? 64.454 60.372 -19.929 1.00 9.48 ? 946 PHE A CE2 1 ATOM 7750 C CZ . PHE A 1 946 ? 65.502 59.557 -19.622 1.00 10.85 ? 946 PHE A CZ 1 ATOM 7751 N N . GLY A 1 947 ? 65.183 59.663 -24.148 1.00 9.04 ? 947 GLY A N 1 ATOM 7752 C CA . GLY A 1 947 ? 64.216 58.583 -24.159 1.00 9.89 ? 947 GLY A CA 1 ATOM 7753 C C . GLY A 1 947 ? 63.865 57.991 -25.512 1.00 9.71 ? 947 GLY A C 1 ATOM 7754 O O . GLY A 1 947 ? 62.921 57.213 -25.643 1.00 10.38 ? 947 GLY A O 1 ATOM 7755 N N . GLY A 1 948 ? 64.649 58.338 -26.543 1.00 12.60 ? 948 GLY A N 1 ATOM 7756 C CA . GLY A 1 948 ? 64.411 57.787 -27.851 1.00 13.58 ? 948 GLY A CA 1 ATOM 7757 C C . GLY A 1 948 ? 64.469 56.266 -27.886 1.00 14.70 ? 948 GLY A C 1 ATOM 7758 O O . GLY A 1 948 ? 63.860 55.667 -28.777 1.00 16.99 ? 948 GLY A O 1 ATOM 7759 N N . ASP A 1 949 ? 65.164 55.649 -26.923 1.00 14.63 ? 949 ASP A N 1 ATOM 7760 C CA . ASP A 1 949 ? 65.255 54.181 -26.877 1.00 16.66 ? 949 ASP A CA 1 ATOM 7761 C C . ASP A 1 949 ? 64.283 53.535 -25.888 1.00 16.11 ? 949 ASP A C 1 ATOM 7762 O O . ASP A 1 949 ? 64.310 52.320 -25.648 1.00 17.37 ? 949 ASP A O 1 ATOM 7763 C CB . ASP A 1 949 ? 66.697 53.733 -26.602 1.00 17.47 ? 949 ASP A CB 1 ATOM 7764 C CG . ASP A 1 949 ? 67.248 54.261 -25.276 1.00 22.13 ? 949 ASP A CG 1 ATOM 7765 O OD1 . ASP A 1 949 ? 66.625 55.149 -24.629 1.00 25.76 ? 949 ASP A OD1 1 ATOM 7766 O OD2 . ASP A 1 949 ? 68.330 53.844 -24.784 1.00 27.71 ? 949 ASP A OD2 1 ATOM 7767 N N . HIS A 1 950 ? 63.401 54.348 -25.300 1.00 13.94 ? 950 HIS A N 1 ATOM 7768 C CA . HIS A 1 950 ? 62.363 53.799 -24.414 1.00 12.70 ? 950 HIS A CA 1 ATOM 7769 C C . HIS A 1 950 ? 61.324 53.057 -25.241 1.00 12.92 ? 950 HIS A C 1 ATOM 7770 O O . HIS A 1 950 ? 60.911 53.531 -26.282 1.00 12.76 ? 950 HIS A O 1 ATOM 7771 C CB . HIS A 1 950 ? 61.643 54.921 -23.645 1.00 11.86 ? 950 HIS A CB 1 ATOM 7772 C CG . HIS A 1 950 ? 62.500 55.641 -22.655 1.00 9.90 ? 950 HIS A CG 1 ATOM 7773 N ND1 . HIS A 1 950 ? 62.117 56.820 -22.057 1.00 9.53 ? 950 HIS A ND1 1 ATOM 7774 C CD2 . HIS A 1 950 ? 63.729 55.356 -22.152 1.00 10.52 ? 950 HIS A CD2 1 ATOM 7775 C CE1 . HIS A 1 950 ? 63.063 57.233 -21.232 1.00 11.14 ? 950 HIS A CE1 1 ATOM 7776 N NE2 . HIS A 1 950 ? 64.060 56.366 -21.275 1.00 11.10 ? 950 HIS A NE2 1 ATOM 7777 N N . PRO A 1 951 ? 60.880 51.893 -24.777 1.00 13.74 ? 951 PRO A N 1 ATOM 7778 C CA . PRO A 1 951 ? 59.849 51.126 -25.483 1.00 14.13 ? 951 PRO A CA 1 ATOM 7779 C C . PRO A 1 951 ? 58.562 51.924 -25.623 1.00 13.49 ? 951 PRO A C 1 ATOM 7780 O O . PRO A 1 951 ? 58.202 52.623 -24.664 1.00 14.09 ? 951 PRO A O 1 ATOM 7781 C CB . PRO A 1 951 ? 59.622 49.912 -24.564 1.00 14.59 ? 951 PRO A CB 1 ATOM 7782 C CG . PRO A 1 951 ? 60.874 49.819 -23.762 1.00 17.45 ? 951 PRO A CG 1 ATOM 7783 C CD . PRO A 1 951 ? 61.348 51.231 -23.542 1.00 14.10 ? 951 PRO A CD 1 ATOM 7784 N N . SER A 1 952 ? 57.903 51.842 -26.772 1.00 12.52 ? 952 SER A N 1 ATOM 7785 C CA . SER A 1 952 ? 56.636 52.522 -27.009 1.00 11.16 ? 952 SER A CA 1 ATOM 7786 C C . SER A 1 952 ? 55.548 51.481 -26.813 1.00 11.67 ? 952 SER A C 1 ATOM 7787 O O . SER A 1 952 ? 55.299 50.634 -27.686 1.00 11.95 ? 952 SER A O 1 ATOM 7788 C CB . SER A 1 952 ? 56.595 53.153 -28.415 1.00 12.29 ? 952 SER A CB 1 ATOM 7789 O OG . SER A 1 952 ? 55.501 54.056 -28.537 1.00 11.72 ? 952 SER A OG 1 ATOM 7790 N N . ALA A 1 953 ? 54.923 51.524 -25.635 1.00 11.27 ? 953 ALA A N 1 ATOM 7791 C CA . ALA A 1 953 ? 53.990 50.475 -25.208 1.00 10.63 ? 953 ALA A CA 1 ATOM 7792 C C . ALA A 1 953 ? 52.639 50.567 -25.900 1.00 10.35 ? 953 ALA A C 1 ATOM 7793 O O . ALA A 1 953 ? 52.252 51.638 -26.416 1.00 9.79 ? 953 ALA A O 1 ATOM 7794 C CB . ALA A 1 953 ? 53.821 50.535 -23.684 1.00 11.62 ? 953 ALA A CB 1 ATOM 7795 N N A ARG A 1 954 ? 51.920 49.450 -25.923 0.50 10.01 ? 954 ARG A N 1 ATOM 7796 N N B ARG A 1 954 ? 51.921 49.450 -25.918 0.50 9.43 ? 954 ARG A N 1 ATOM 7797 C CA A ARG A 1 954 ? 50.563 49.423 -26.428 0.50 10.92 ? 954 ARG A CA 1 ATOM 7798 C CA B ARG A 1 954 ? 50.571 49.437 -26.426 0.50 9.75 ? 954 ARG A CA 1 ATOM 7799 C C A ARG A 1 954 ? 49.717 50.530 -25.791 0.50 10.14 ? 954 ARG A C 1 ATOM 7800 C C B ARG A 1 954 ? 49.719 50.535 -25.789 0.50 9.57 ? 954 ARG A C 1 ATOM 7801 O O A ARG A 1 954 ? 49.854 50.827 -24.623 0.50 10.15 ? 954 ARG A O 1 ATOM 7802 O O B ARG A 1 954 ? 49.852 50.830 -24.621 0.50 9.72 ? 954 ARG A O 1 ATOM 7803 C CB A ARG A 1 954 ? 49.915 48.052 -26.187 0.50 11.18 ? 954 ARG A CB 1 ATOM 7804 C CB B ARG A 1 954 ? 49.898 48.072 -26.256 0.50 9.85 ? 954 ARG A CB 1 ATOM 7805 C CG A ARG A 1 954 ? 48.772 47.699 -27.149 0.50 14.02 ? 954 ARG A CG 1 ATOM 7806 C CG B ARG A 1 954 ? 48.705 47.918 -27.205 0.50 11.32 ? 954 ARG A CG 1 ATOM 7807 C CD A ARG A 1 954 ? 48.170 46.320 -26.781 0.50 13.58 ? 954 ARG A CD 1 ATOM 7808 C CD B ARG A 1 954 ? 48.203 46.492 -27.324 0.50 10.30 ? 954 ARG A CD 1 ATOM 7809 N NE A ARG A 1 954 ? 48.027 46.233 -25.329 0.50 19.63 ? 954 ARG A NE 1 ATOM 7810 N NE B ARG A 1 954 ? 47.256 46.186 -26.278 0.50 10.34 ? 954 ARG A NE 1 ATOM 7811 C CZ A ARG A 1 954 ? 48.933 45.757 -24.459 0.50 19.15 ? 954 ARG A CZ 1 ATOM 7812 C CZ B ARG A 1 954 ? 46.635 45.025 -26.153 0.50 12.95 ? 954 ARG A CZ 1 ATOM 7813 N NH1 A ARG A 1 954 ? 50.115 45.231 -24.850 0.50 15.00 ? 954 ARG A NH1 1 ATOM 7814 N NH1 B ARG A 1 954 ? 46.865 44.045 -27.021 0.50 13.22 ? 954 ARG A NH1 1 ATOM 7815 N NH2 A ARG A 1 954 ? 48.618 45.787 -23.166 0.50 20.49 ? 954 ARG A NH2 1 ATOM 7816 N NH2 B ARG A 1 954 ? 45.791 44.824 -25.171 0.50 12.77 ? 954 ARG A NH2 1 ATOM 7817 N N . GLU A 1 955 ? 48.814 51.095 -26.582 1.00 9.24 ? 955 GLU A N 1 ATOM 7818 C CA . GLU A 1 955 ? 48.107 52.307 -26.181 1.00 10.60 ? 955 GLU A CA 1 ATOM 7819 C C . GLU A 1 955 ? 47.266 52.190 -24.914 1.00 9.53 ? 955 GLU A C 1 ATOM 7820 O O . GLU A 1 955 ? 46.983 53.209 -24.278 1.00 10.42 ? 955 GLU A O 1 ATOM 7821 C CB . GLU A 1 955 ? 47.222 52.800 -27.308 1.00 11.87 ? 955 GLU A CB 1 ATOM 7822 C CG . GLU A 1 955 ? 46.206 51.751 -27.738 1.00 14.35 ? 955 GLU A CG 1 ATOM 7823 C CD . GLU A 1 955 ? 45.214 52.265 -28.750 1.00 19.59 ? 955 GLU A CD 1 ATOM 7824 O OE1 . GLU A 1 955 ? 45.023 53.501 -28.827 1.00 24.32 ? 955 GLU A OE1 1 ATOM 7825 O OE2 . GLU A 1 955 ? 44.657 51.428 -29.488 1.00 22.25 ? 955 GLU A OE2 1 ATOM 7826 N N . ASP A 1 956 ? 46.839 50.975 -24.566 1.00 8.28 ? 956 ASP A N 1 ATOM 7827 C CA . ASP A 1 956 ? 46.026 50.790 -23.369 1.00 8.42 ? 956 ASP A CA 1 ATOM 7828 C C . ASP A 1 956 ? 46.843 50.647 -22.095 1.00 8.02 ? 956 ASP A C 1 ATOM 7829 O O . ASP A 1 956 ? 46.253 50.581 -21.019 1.00 8.77 ? 956 ASP A O 1 ATOM 7830 C CB . ASP A 1 956 ? 45.037 49.638 -23.515 1.00 9.08 ? 956 ASP A CB 1 ATOM 7831 C CG . ASP A 1 956 ? 45.680 48.332 -23.907 1.00 11.39 ? 956 ASP A CG 1 ATOM 7832 O OD1 . ASP A 1 956 ? 46.919 48.256 -24.093 1.00 13.76 ? 956 ASP A OD1 1 ATOM 7833 O OD2 . ASP A 1 956 ? 44.965 47.298 -24.022 1.00 13.45 ? 956 ASP A OD2 1 ATOM 7834 N N . LEU A 1 957 ? 48.161 50.673 -22.190 1.00 7.86 ? 957 LEU A N 1 ATOM 7835 C CA . LEU A 1 957 ? 49.011 50.541 -21.013 1.00 9.31 ? 957 LEU A CA 1 ATOM 7836 C C . LEU A 1 957 ? 49.566 51.883 -20.574 1.00 8.28 ? 957 LEU A C 1 ATOM 7837 O O . LEU A 1 957 ? 49.994 52.673 -21.430 1.00 9.51 ? 957 LEU A O 1 ATOM 7838 C CB . LEU A 1 957 ? 50.165 49.590 -21.334 1.00 9.74 ? 957 LEU A CB 1 ATOM 7839 C CG . LEU A 1 957 ? 51.054 49.095 -20.201 1.00 13.28 ? 957 LEU A CG 1 ATOM 7840 C CD1 . LEU A 1 957 ? 50.196 48.312 -19.234 1.00 14.72 ? 957 LEU A CD1 1 ATOM 7841 C CD2 . LEU A 1 957 ? 52.144 48.198 -20.773 1.00 13.23 ? 957 LEU A CD2 1 ATOM 7842 N N . ASP A 1 958 ? 49.567 52.139 -19.268 1.00 7.70 ? 958 ASP A N 1 ATOM 7843 C CA . ASP A 1 958 ? 50.192 53.317 -18.743 1.00 7.42 ? 958 ASP A CA 1 ATOM 7844 C C . ASP A 1 958 ? 51.150 52.981 -17.611 1.00 7.11 ? 958 ASP A C 1 ATOM 7845 O O . ASP A 1 958 ? 50.924 52.013 -16.881 1.00 7.90 ? 958 ASP A O 1 ATOM 7846 C CB . ASP A 1 958 ? 49.132 54.284 -18.244 1.00 7.60 ? 958 ASP A CB 1 ATOM 7847 C CG . ASP A 1 958 ? 49.662 55.704 -18.066 1.00 9.00 ? 958 ASP A CG 1 ATOM 7848 O OD1 . ASP A 1 958 ? 50.785 56.047 -18.550 1.00 8.23 ? 958 ASP A OD1 1 ATOM 7849 O OD2 . ASP A 1 958 ? 48.991 56.549 -17.426 1.00 10.12 ? 958 ASP A OD2 1 ATOM 7850 N N . VAL A 1 959 ? 52.208 53.779 -17.492 1.00 6.53 ? 959 VAL A N 1 ATOM 7851 C CA . VAL A 1 959 ? 53.043 53.797 -16.314 1.00 6.22 ? 959 VAL A CA 1 ATOM 7852 C C . VAL A 1 959 ? 52.487 54.894 -15.417 1.00 6.89 ? 959 VAL A C 1 ATOM 7853 O O . VAL A 1 959 ? 52.902 56.056 -15.499 1.00 7.44 ? 959 VAL A O 1 ATOM 7854 C CB . VAL A 1 959 ? 54.535 54.046 -16.677 1.00 7.52 ? 959 VAL A CB 1 ATOM 7855 C CG1 . VAL A 1 959 ? 55.364 54.190 -15.404 1.00 7.74 ? 959 VAL A CG1 1 ATOM 7856 C CG2 . VAL A 1 959 ? 55.064 52.852 -17.513 1.00 7.59 ? 959 VAL A CG2 1 ATOM 7857 N N . SER A 1 960 ? 51.532 54.531 -14.569 1.00 6.51 ? 960 SER A N 1 ATOM 7858 C CA . SER A 1 960 ? 50.794 55.489 -13.742 1.00 7.17 ? 960 SER A CA 1 ATOM 7859 C C . SER A 1 960 ? 51.698 56.219 -12.750 1.00 7.95 ? 960 SER A C 1 ATOM 7860 O O . SER A 1 960 ? 51.500 57.419 -12.457 1.00 9.61 ? 960 SER A O 1 ATOM 7861 C CB . SER A 1 960 ? 49.674 54.766 -13.006 1.00 7.72 ? 960 SER A CB 1 ATOM 7862 O OG . SER A 1 960 ? 48.855 54.038 -13.931 1.00 9.99 ? 960 SER A OG 1 ATOM 7863 N N . VAL A 1 961 ? 52.677 55.470 -12.224 1.00 6.73 ? 961 VAL A N 1 ATOM 7864 C CA . VAL A 1 961 ? 53.638 55.968 -11.251 1.00 6.90 ? 961 VAL A CA 1 ATOM 7865 C C . VAL A 1 961 ? 55.003 55.433 -11.642 1.00 6.36 ? 961 VAL A C 1 ATOM 7866 O O . VAL A 1 961 ? 55.158 54.248 -11.942 1.00 6.19 ? 961 VAL A O 1 ATOM 7867 C CB . VAL A 1 961 ? 53.314 55.466 -9.817 1.00 7.66 ? 961 VAL A CB 1 ATOM 7868 C CG1 . VAL A 1 961 ? 54.406 55.912 -8.832 1.00 9.86 ? 961 VAL A CG1 1 ATOM 7869 C CG2 . VAL A 1 961 ? 51.916 55.982 -9.344 1.00 9.56 ? 961 VAL A CG2 1 ATOM 7870 N N . MET A 1 962 ? 56.002 56.320 -11.597 1.00 6.67 ? 962 MET A N 1 ATOM 7871 C CA . MET A 1 962 ? 57.393 55.921 -11.559 1.00 6.15 ? 962 MET A CA 1 ATOM 7872 C C . MET A 1 962 ? 57.992 56.777 -10.451 1.00 6.91 ? 962 MET A C 1 ATOM 7873 O O . MET A 1 962 ? 57.906 58.004 -10.481 1.00 7.48 ? 962 MET A O 1 ATOM 7874 C CB . MET A 1 962 ? 58.084 56.201 -12.918 1.00 7.37 ? 962 MET A CB 1 ATOM 7875 C CG . MET A 1 962 ? 59.596 55.911 -12.856 1.00 7.52 ? 962 MET A CG 1 ATOM 7876 S SD . MET A 1 962 ? 60.299 56.249 -14.486 1.00 9.62 ? 962 MET A SD 1 ATOM 7877 C CE . MET A 1 962 ? 62.074 55.946 -14.170 1.00 9.99 ? 962 MET A CE 1 ATOM 7878 N N . ARG A 1 963 ? 58.541 56.120 -9.443 1.00 6.03 ? 963 ARG A N 1 ATOM 7879 C CA . ARG A 1 963 ? 59.045 56.784 -8.250 1.00 6.56 ? 963 ARG A CA 1 ATOM 7880 C C . ARG A 1 963 ? 60.311 56.113 -7.741 1.00 6.40 ? 963 ARG A C 1 ATOM 7881 O O . ARG A 1 963 ? 60.277 54.937 -7.429 1.00 6.52 ? 963 ARG A O 1 ATOM 7882 C CB . ARG A 1 963 ? 57.982 56.746 -7.140 1.00 6.71 ? 963 ARG A CB 1 ATOM 7883 C CG . ARG A 1 963 ? 58.423 57.393 -5.816 1.00 8.18 ? 963 ARG A CG 1 ATOM 7884 C CD . ARG A 1 963 ? 57.339 57.243 -4.716 1.00 9.70 ? 963 ARG A CD 1 ATOM 7885 N NE . ARG A 1 963 ? 56.121 57.867 -5.199 1.00 9.38 ? 963 ARG A NE 1 ATOM 7886 C CZ . ARG A 1 963 ? 54.915 57.333 -5.159 1.00 10.19 ? 963 ARG A CZ 1 ATOM 7887 N NH1 . ARG A 1 963 ? 54.681 56.166 -4.585 1.00 9.73 ? 963 ARG A NH1 1 ATOM 7888 N NH2 . ARG A 1 963 ? 53.926 57.999 -5.692 1.00 9.88 ? 963 ARG A NH2 1 ATOM 7889 N N . ARG A 1 964 ? 61.401 56.878 -7.615 1.00 6.24 ? 964 ARG A N 1 ATOM 7890 C CA . ARG A 1 964 ? 62.576 56.293 -6.974 1.00 7.52 ? 964 ARG A CA 1 ATOM 7891 C C . ARG A 1 964 ? 62.291 56.260 -5.490 1.00 7.44 ? 964 ARG A C 1 ATOM 7892 O O . ARG A 1 964 ? 61.830 57.224 -4.897 1.00 8.28 ? 964 ARG A O 1 ATOM 7893 C CB . ARG A 1 964 ? 63.811 57.127 -7.290 1.00 7.44 ? 964 ARG A CB 1 ATOM 7894 C CG . ARG A 1 964 ? 65.057 56.516 -6.695 1.00 8.88 ? 964 ARG A CG 1 ATOM 7895 C CD . ARG A 1 964 ? 66.345 57.165 -7.162 1.00 9.18 ? 964 ARG A CD 1 ATOM 7896 N NE . ARG A 1 964 ? 66.519 56.999 -8.591 1.00 9.54 ? 964 ARG A NE 1 ATOM 7897 C CZ . ARG A 1 964 ? 67.440 56.247 -9.156 1.00 9.68 ? 964 ARG A CZ 1 ATOM 7898 N NH1 . ARG A 1 964 ? 68.286 55.536 -8.397 1.00 12.28 ? 964 ARG A NH1 1 ATOM 7899 N NH2 . ARG A 1 964 ? 67.546 56.184 -10.463 1.00 11.13 ? 964 ARG A NH2 1 ATOM 7900 N N . LEU A 1 965 ? 62.558 55.104 -4.902 1.00 6.69 ? 965 LEU A N 1 ATOM 7901 C CA . LEU A 1 965 ? 62.179 54.811 -3.522 1.00 7.57 ? 965 LEU A CA 1 ATOM 7902 C C . LEU A 1 965 ? 63.302 54.974 -2.508 1.00 8.82 ? 965 LEU A C 1 ATOM 7903 O O . LEU A 1 965 ? 63.066 54.911 -1.302 1.00 10.10 ? 965 LEU A O 1 ATOM 7904 C CB . LEU A 1 965 ? 61.627 53.391 -3.418 1.00 8.17 ? 965 LEU A CB 1 ATOM 7905 C CG . LEU A 1 965 ? 60.403 53.140 -4.314 1.00 7.75 ? 965 LEU A CG 1 ATOM 7906 C CD1 . LEU A 1 965 ? 59.999 51.664 -4.312 1.00 9.68 ? 965 LEU A CD1 1 ATOM 7907 C CD2 . LEU A 1 965 ? 59.231 54.010 -3.908 1.00 10.70 ? 965 LEU A CD2 1 ATOM 7908 N N . THR A 1 966 ? 64.524 55.146 -3.019 1.00 8.87 ? 966 THR A N 1 ATOM 7909 C CA . THR A 1 966 ? 65.732 55.223 -2.198 1.00 9.57 ? 966 THR A CA 1 ATOM 7910 C C . THR A 1 966 ? 66.435 56.538 -2.376 1.00 9.55 ? 966 THR A C 1 ATOM 7911 O O . THR A 1 966 ? 66.435 57.092 -3.473 1.00 9.56 ? 966 THR A O 1 ATOM 7912 C CB . THR A 1 966 ? 66.725 54.123 -2.602 1.00 9.30 ? 966 THR A CB 1 ATOM 7913 O OG1 . THR A 1 966 ? 66.758 54.022 -4.022 1.00 10.01 ? 966 THR A OG1 1 ATOM 7914 C CG2 . THR A 1 966 ? 66.267 52.737 -2.101 1.00 10.80 ? 966 THR A CG2 1 ATOM 7915 N N . LYS A 1 967 ? 67.062 57.002 -1.311 1.00 10.72 ? 967 LYS A N 1 ATOM 7916 C CA . LYS A 1 967 ? 67.902 58.199 -1.353 1.00 11.77 ? 967 LYS A CA 1 ATOM 7917 C C . LYS A 1 967 ? 69.293 57.817 -1.859 1.00 12.38 ? 967 LYS A C 1 ATOM 7918 O O . LYS A 1 967 ? 69.583 56.628 -2.024 1.00 11.11 ? 967 LYS A O 1 ATOM 7919 C CB . LYS A 1 967 ? 68.023 58.807 0.033 1.00 12.58 ? 967 LYS A CB 1 ATOM 7920 C CG . LYS A 1 967 ? 66.679 59.320 0.562 1.00 17.05 ? 967 LYS A CG 1 ATOM 7921 C CD . LYS A 1 967 ? 66.865 60.397 1.621 1.00 22.22 ? 967 LYS A CD 1 ATOM 7922 C CE . LYS A 1 967 ? 65.581 60.670 2.398 1.00 28.35 ? 967 LYS A CE 1 ATOM 7923 N NZ . LYS A 1 967 ? 64.589 61.441 1.602 1.00 32.02 ? 967 LYS A NZ 1 ATOM 7924 N N . SER A 1 968 ? 70.120 58.826 -2.143 1.00 12.94 ? 968 SER A N 1 ATOM 7925 C CA . SER A 1 968 ? 71.344 58.577 -2.897 1.00 14.97 ? 968 SER A CA 1 ATOM 7926 C C . SER A 1 968 ? 72.369 57.754 -2.136 1.00 15.12 ? 968 SER A C 1 ATOM 7927 O O . SER A 1 968 ? 73.204 57.122 -2.780 1.00 16.55 ? 968 SER A O 1 ATOM 7928 C CB . SER A 1 968 ? 71.990 59.881 -3.347 1.00 16.04 ? 968 SER A CB 1 ATOM 7929 O OG . SER A 1 968 ? 72.274 60.680 -2.231 1.00 19.53 ? 968 SER A OG 1 ATOM 7930 N N . SER A 1 969 ? 72.306 57.746 -0.810 1.00 15.31 ? 969 SER A N 1 ATOM 7931 C CA . SER A 1 969 ? 73.312 56.980 -0.037 1.00 16.71 ? 969 SER A CA 1 ATOM 7932 C C . SER A 1 969 ? 73.047 55.469 0.000 1.00 16.53 ? 969 SER A C 1 ATOM 7933 O O . SER A 1 969 ? 73.887 54.693 0.472 1.00 16.98 ? 969 SER A O 1 ATOM 7934 C CB . SER A 1 969 ? 73.444 57.535 1.367 1.00 18.42 ? 969 SER A CB 1 ATOM 7935 O OG . SER A 1 969 ? 72.329 57.138 2.145 1.00 23.03 ? 969 SER A OG 1 ATOM 7936 N N . ALA A 1 970 ? 71.897 55.026 -0.504 1.00 14.31 ? 970 ALA A N 1 ATOM 7937 C CA . ALA A 1 970 ? 71.618 53.604 -0.525 1.00 14.54 ? 970 ALA A CA 1 ATOM 7938 C C . ALA A 1 970 ? 72.425 52.852 -1.577 1.00 15.19 ? 970 ALA A C 1 ATOM 7939 O O . ALA A 1 970 ? 72.418 53.192 -2.768 1.00 15.26 ? 970 ALA A O 1 ATOM 7940 C CB . ALA A 1 970 ? 70.109 53.320 -0.662 1.00 15.59 ? 970 ALA A CB 1 ATOM 7941 N N A LYS A 1 971 ? 73.146 51.844 -1.092 0.50 15.29 ? 971 LYS A N 1 ATOM 7942 N N B LYS A 1 971 ? 73.135 51.798 -1.157 0.50 15.05 ? 971 LYS A N 1 ATOM 7943 C CA A LYS A 1 971 ? 73.880 50.921 -1.934 0.50 16.01 ? 971 LYS A CA 1 ATOM 7944 C CA B LYS A 1 971 ? 73.914 50.976 -2.095 0.50 15.58 ? 971 LYS A CA 1 ATOM 7945 C C A LYS A 1 971 ? 73.001 50.395 -3.064 0.50 15.26 ? 971 LYS A C 1 ATOM 7946 C C B LYS A 1 971 ? 73.039 50.246 -3.119 0.50 15.02 ? 971 LYS A C 1 ATOM 7947 O O A LYS A 1 971 ? 73.359 50.526 -4.233 0.50 15.23 ? 971 LYS A O 1 ATOM 7948 O O B LYS A 1 971 ? 73.450 50.035 -4.271 0.50 14.97 ? 971 LYS A O 1 ATOM 7949 C CB A LYS A 1 971 ? 74.412 49.772 -1.066 0.50 15.90 ? 971 LYS A CB 1 ATOM 7950 C CB B LYS A 1 971 ? 74.793 49.964 -1.339 0.50 15.21 ? 971 LYS A CB 1 ATOM 7951 C CG A LYS A 1 971 ? 75.132 48.673 -1.816 0.50 17.40 ? 971 LYS A CG 1 ATOM 7952 C CG B LYS A 1 971 ? 75.685 49.119 -2.239 0.50 17.43 ? 971 LYS A CG 1 ATOM 7953 C CD A LYS A 1 971 ? 75.939 47.765 -0.862 0.50 17.81 ? 971 LYS A CD 1 ATOM 7954 C CD B LYS A 1 971 ? 76.579 48.187 -1.414 0.50 16.74 ? 971 LYS A CD 1 ATOM 7955 C CE A LYS A 1 971 ? 76.660 48.540 0.219 0.50 21.21 ? 971 LYS A CE 1 ATOM 7956 C CE B LYS A 1 971 ? 77.009 46.951 -2.194 0.50 19.48 ? 971 LYS A CE 1 ATOM 7957 N NZ A LYS A 1 971 ? 77.563 49.591 -0.319 0.50 23.51 ? 971 LYS A NZ 1 ATOM 7958 N NZ B LYS A 1 971 ? 77.452 47.248 -3.574 0.50 20.72 ? 971 LYS A NZ 1 ATOM 7959 N N . THR A 1 972 ? 71.844 49.839 -2.698 1.00 14.86 ? 972 THR A N 1 ATOM 7960 C CA . THR A 1 972 ? 70.922 49.243 -3.648 1.00 14.50 ? 972 THR A CA 1 ATOM 7961 C C . THR A 1 972 ? 69.811 50.257 -3.909 1.00 12.26 ? 972 THR A C 1 ATOM 7962 O O . THR A 1 972 ? 69.020 50.535 -3.021 1.00 13.36 ? 972 THR A O 1 ATOM 7963 C CB . THR A 1 972 ? 70.335 47.945 -3.120 1.00 16.21 ? 972 THR A CB 1 ATOM 7964 O OG1 . THR A 1 972 ? 71.413 47.021 -2.897 1.00 18.84 ? 972 THR A OG1 1 ATOM 7965 C CG2 . THR A 1 972 ? 69.523 47.258 -4.212 1.00 16.77 ? 972 THR A CG2 1 ATOM 7966 N N . GLN A 1 973 ? 69.797 50.829 -5.108 1.00 10.30 ? 973 GLN A N 1 ATOM 7967 C CA . GLN A 1 973 ? 68.733 51.773 -5.479 1.00 10.94 ? 973 GLN A CA 1 ATOM 7968 C C . GLN A 1 973 ? 67.504 50.989 -5.842 1.00 10.23 ? 973 GLN A C 1 ATOM 7969 O O . GLN A 1 973 ? 67.594 49.912 -6.416 1.00 10.61 ? 973 GLN A O 1 ATOM 7970 C CB . GLN A 1 973 ? 69.185 52.644 -6.641 1.00 10.77 ? 973 GLN A CB 1 ATOM 7971 C CG . GLN A 1 973 ? 70.273 53.628 -6.199 1.00 10.15 ? 973 GLN A CG 1 ATOM 7972 C CD . GLN A 1 973 ? 69.790 54.692 -5.233 1.00 11.90 ? 973 GLN A CD 1 ATOM 7973 O OE1 . GLN A 1 973 ? 68.790 55.364 -5.514 1.00 10.80 ? 973 GLN A OE1 1 ATOM 7974 N NE2 . GLN A 1 973 ? 70.485 54.875 -4.114 1.00 10.14 ? 973 GLN A NE2 1 ATOM 7975 N N . ARG A 1 974 ? 66.340 51.565 -5.527 1.00 10.34 ? 974 ARG A N 1 ATOM 7976 C CA A ARG A 1 974 ? 65.086 50.929 -5.888 0.50 9.44 ? 974 ARG A CA 1 ATOM 7977 C CA B ARG A 1 974 ? 65.052 50.937 -5.790 0.50 9.92 ? 974 ARG A CA 1 ATOM 7978 C C . ARG A 1 974 ? 64.143 51.920 -6.540 1.00 8.95 ? 974 ARG A C 1 ATOM 7979 O O . ARG A 1 974 ? 64.036 53.053 -6.098 1.00 9.31 ? 974 ARG A O 1 ATOM 7980 C CB A ARG A 1 974 ? 64.412 50.300 -4.683 0.50 10.22 ? 974 ARG A CB 1 ATOM 7981 C CB B ARG A 1 974 ? 64.393 50.529 -4.468 0.50 10.53 ? 974 ARG A CB 1 ATOM 7982 C CG A ARG A 1 974 ? 65.259 49.243 -3.991 0.50 10.59 ? 974 ARG A CG 1 ATOM 7983 C CG B ARG A 1 974 ? 65.067 49.333 -3.758 0.50 11.37 ? 974 ARG A CG 1 ATOM 7984 C CD A ARG A 1 974 ? 64.758 48.875 -2.606 0.50 13.01 ? 974 ARG A CD 1 ATOM 7985 C CD B ARG A 1 974 ? 64.690 49.148 -2.273 0.50 12.14 ? 974 ARG A CD 1 ATOM 7986 N NE A ARG A 1 974 ? 63.530 48.098 -2.679 0.50 12.71 ? 974 ARG A NE 1 ATOM 7987 N NE B ARG A 1 974 ? 63.256 49.225 -2.014 0.50 15.38 ? 974 ARG A NE 1 ATOM 7988 C CZ A ARG A 1 974 ? 62.337 48.455 -2.189 0.50 13.94 ? 974 ARG A CZ 1 ATOM 7989 C CZ B ARG A 1 974 ? 62.379 48.228 -2.134 0.50 18.38 ? 974 ARG A CZ 1 ATOM 7990 N NH1 A ARG A 1 974 ? 62.160 49.596 -1.524 0.50 10.68 ? 974 ARG A NH1 1 ATOM 7991 N NH1 B ARG A 1 974 ? 62.754 47.004 -2.512 0.50 18.28 ? 974 ARG A NH1 1 ATOM 7992 N NH2 A ARG A 1 974 ? 61.314 47.623 -2.345 0.50 10.82 ? 974 ARG A NH2 1 ATOM 7993 N NH2 B ARG A 1 974 ? 61.103 48.462 -1.865 0.50 16.54 ? 974 ARG A NH2 1 ATOM 7994 N N . VAL A 1 975 ? 63.484 51.456 -7.598 1.00 8.35 ? 975 VAL A N 1 ATOM 7995 C CA . VAL A 1 975 ? 62.530 52.319 -8.313 1.00 8.90 ? 975 VAL A CA 1 ATOM 7996 C C . VAL A 1 975 ? 61.234 51.543 -8.412 1.00 7.22 ? 975 VAL A C 1 ATOM 7997 O O . VAL A 1 975 ? 61.200 50.381 -8.853 1.00 8.20 ? 975 VAL A O 1 ATOM 7998 C CB . VAL A 1 975 ? 63.062 52.728 -9.710 1.00 9.21 ? 975 VAL A CB 1 ATOM 7999 C CG1 . VAL A 1 975 ? 62.075 53.663 -10.466 1.00 8.85 ? 975 VAL A CG1 1 ATOM 8000 C CG2 . VAL A 1 975 ? 64.411 53.460 -9.583 1.00 11.56 ? 975 VAL A CG2 1 ATOM 8001 N N . GLY A 1 976 ? 60.159 52.225 -8.041 1.00 6.73 ? 976 GLY A N 1 ATOM 8002 C CA . GLY A 1 976 ? 58.838 51.623 -8.071 1.00 6.40 ? 976 GLY A CA 1 ATOM 8003 C C . GLY A 1 976 ? 58.020 52.107 -9.255 1.00 6.89 ? 976 GLY A C 1 ATOM 8004 O O . GLY A 1 976 ? 58.102 53.282 -9.619 1.00 6.72 ? 976 GLY A O 1 ATOM 8005 N N . TYR A 1 977 ? 57.272 51.186 -9.851 1.00 6.12 ? 977 TYR A N 1 ATOM 8006 C CA . TYR A 1 977 ? 56.397 51.475 -10.974 1.00 5.84 ? 977 TYR A CA 1 ATOM 8007 C C . TYR A 1 977 ? 55.016 50.940 -10.702 1.00 7.01 ? 977 TYR A C 1 ATOM 8008 O O . TYR A 1 977 ? 54.878 49.819 -10.174 1.00 6.51 ? 977 TYR A O 1 ATOM 8009 C CB . TYR A 1 977 ? 56.878 50.755 -12.228 1.00 6.65 ? 977 TYR A CB 1 ATOM 8010 C CG . TYR A 1 977 ? 58.263 51.136 -12.645 1.00 6.42 ? 977 TYR A CG 1 ATOM 8011 C CD1 . TYR A 1 977 ? 58.483 52.223 -13.506 1.00 7.45 ? 977 TYR A CD1 1 ATOM 8012 C CD2 . TYR A 1 977 ? 59.362 50.421 -12.159 1.00 7.14 ? 977 TYR A CD2 1 ATOM 8013 C CE1 . TYR A 1 977 ? 59.754 52.566 -13.907 1.00 9.50 ? 977 TYR A CE1 1 ATOM 8014 C CE2 . TYR A 1 977 ? 60.662 50.782 -12.545 1.00 9.78 ? 977 TYR A CE2 1 ATOM 8015 C CZ . TYR A 1 977 ? 60.833 51.864 -13.419 1.00 7.47 ? 977 TYR A CZ 1 ATOM 8016 O OH . TYR A 1 977 ? 62.096 52.296 -13.856 1.00 10.10 ? 977 TYR A OH 1 ATOM 8017 N N . VAL A 1 978 ? 54.000 51.731 -11.039 1.00 6.64 ? 978 VAL A N 1 ATOM 8018 C CA . VAL A 1 978 ? 52.629 51.222 -11.047 1.00 6.42 ? 978 VAL A CA 1 ATOM 8019 C C . VAL A 1 978 ? 52.182 51.173 -12.514 1.00 6.75 ? 978 VAL A C 1 ATOM 8020 O O . VAL A 1 978 ? 52.281 52.223 -13.206 1.00 6.65 ? 978 VAL A O 1 ATOM 8021 C CB . VAL A 1 978 ? 51.662 52.063 -10.210 1.00 6.68 ? 978 VAL A CB 1 ATOM 8022 C CG1 . VAL A 1 978 ? 50.219 51.572 -10.396 1.00 8.20 ? 978 VAL A CG1 1 ATOM 8023 C CG2 . VAL A 1 978 ? 52.049 52.010 -8.761 1.00 7.57 ? 978 VAL A CG2 1 ATOM 8024 N N A LEU A 1 979 ? 51.824 49.985 -13.001 0.50 6.07 ? 979 LEU A N 1 ATOM 8025 N N B LEU A 1 979 ? 51.747 50.001 -12.983 0.50 6.57 ? 979 LEU A N 1 ATOM 8026 C CA A LEU A 1 979 ? 51.327 49.820 -14.350 0.50 6.74 ? 979 LEU A CA 1 ATOM 8027 C CA B LEU A 1 979 ? 51.406 49.757 -14.375 0.50 8.00 ? 979 LEU A CA 1 ATOM 8028 C C A LEU A 1 979 ? 49.857 49.649 -14.282 0.50 6.89 ? 979 LEU A C 1 ATOM 8029 C C B LEU A 1 979 ? 49.933 49.452 -14.466 0.50 7.30 ? 979 LEU A C 1 ATOM 8030 O O A LEU A 1 979 ? 49.331 48.978 -13.405 0.50 6.73 ? 979 LEU A O 1 ATOM 8031 O O B LEU A 1 979 ? 49.480 48.481 -13.846 0.50 7.00 ? 979 LEU A O 1 ATOM 8032 C CB A LEU A 1 979 ? 51.915 48.583 -15.030 0.50 7.33 ? 979 LEU A CB 1 ATOM 8033 C CB B LEU A 1 979 ? 52.177 48.523 -14.860 0.50 8.37 ? 979 LEU A CB 1 ATOM 8034 C CG A LEU A 1 979 ? 53.426 48.602 -15.254 0.50 8.75 ? 979 LEU A CG 1 ATOM 8035 C CG B LEU A 1 979 ? 52.281 48.276 -16.359 0.50 11.00 ? 979 LEU A CG 1 ATOM 8036 C CD1 A LEU A 1 979 ? 53.826 47.530 -16.242 0.50 12.08 ? 979 LEU A CD1 1 ATOM 8037 C CD1 B LEU A 1 979 ? 53.181 49.339 -16.944 0.50 13.28 ? 979 LEU A CD1 1 ATOM 8038 C CD2 A LEU A 1 979 ? 53.894 49.956 -15.741 0.50 11.17 ? 979 LEU A CD2 1 ATOM 8039 C CD2 B LEU A 1 979 ? 52.829 46.884 -16.651 0.50 10.74 ? 979 LEU A CD2 1 ATOM 8040 N N . HIS A 1 980 ? 49.190 50.267 -15.223 1.00 7.17 ? 980 HIS A N 1 ATOM 8041 C CA . HIS A 1 980 ? 47.752 50.083 -15.358 1.00 7.02 ? 980 HIS A CA 1 ATOM 8042 C C . HIS A 1 980 ? 47.391 49.840 -16.806 1.00 8.08 ? 980 HIS A C 1 ATOM 8043 O O . HIS A 1 980 ? 47.822 50.609 -17.664 1.00 8.78 ? 980 HIS A O 1 ATOM 8044 C CB . HIS A 1 980 ? 46.986 51.325 -14.896 1.00 8.21 ? 980 HIS A CB 1 ATOM 8045 C CG . HIS A 1 980 ? 45.513 51.185 -15.104 1.00 8.97 ? 980 HIS A CG 1 ATOM 8046 N ND1 . HIS A 1 980 ? 44.766 50.290 -14.375 1.00 10.10 ? 980 HIS A ND1 1 ATOM 8047 C CD2 . HIS A 1 980 ? 44.660 51.757 -15.990 1.00 9.45 ? 980 HIS A CD2 1 ATOM 8048 C CE1 . HIS A 1 980 ? 43.509 50.316 -14.802 1.00 10.23 ? 980 HIS A CE1 1 ATOM 8049 N NE2 . HIS A 1 980 ? 43.416 51.213 -15.771 1.00 9.55 ? 980 HIS A NE2 1 ATOM 8050 N N A ARG A 1 981 ? 46.565 48.833 -17.058 0.50 7.71 ? 981 ARG A N 1 ATOM 8051 N N B ARG A 1 981 ? 46.647 48.775 -17.107 0.50 7.41 ? 981 ARG A N 1 ATOM 8052 C CA A ARG A 1 981 ? 46.099 48.597 -18.401 0.50 8.02 ? 981 ARG A CA 1 ATOM 8053 C CA B ARG A 1 981 ? 46.110 48.656 -18.457 0.50 7.35 ? 981 ARG A CA 1 ATOM 8054 C C A ARG A 1 981 ? 44.614 48.772 -18.423 0.50 7.47 ? 981 ARG A C 1 ATOM 8055 C C B ARG A 1 981 ? 44.641 48.843 -18.368 0.50 6.97 ? 981 ARG A C 1 ATOM 8056 O O A ARG A 1 981 ? 43.905 48.051 -17.737 0.50 7.92 ? 981 ARG A O 1 ATOM 8057 O O B ARG A 1 981 ? 43.983 48.217 -17.541 0.50 7.31 ? 981 ARG A O 1 ATOM 8058 C CB A ARG A 1 981 ? 46.487 47.190 -18.829 0.50 8.87 ? 981 ARG A CB 1 ATOM 8059 C CB B ARG A 1 981 ? 46.428 47.310 -19.109 0.50 8.03 ? 981 ARG A CB 1 ATOM 8060 C CG A ARG A 1 981 ? 45.977 46.826 -20.184 0.50 11.14 ? 981 ARG A CG 1 ATOM 8061 C CG B ARG A 1 981 ? 46.144 47.276 -20.637 0.50 7.23 ? 981 ARG A CG 1 ATOM 8062 C CD A ARG A 1 981 ? 46.815 45.793 -20.894 0.50 15.34 ? 981 ARG A CD 1 ATOM 8063 C CD B ARG A 1 981 ? 46.177 45.859 -21.245 0.50 8.38 ? 981 ARG A CD 1 ATOM 8064 N NE A ARG A 1 981 ? 46.173 45.358 -22.125 0.50 17.47 ? 981 ARG A NE 1 ATOM 8065 N NE B ARG A 1 981 ? 47.472 45.226 -21.034 0.50 10.15 ? 981 ARG A NE 1 ATOM 8066 C CZ A ARG A 1 981 ? 46.327 44.154 -22.658 0.50 20.06 ? 981 ARG A CZ 1 ATOM 8067 C CZ B ARG A 1 981 ? 48.473 45.264 -21.895 0.50 8.75 ? 981 ARG A CZ 1 ATOM 8068 N NH1 A ARG A 1 981 ? 47.101 43.252 -22.067 0.50 19.50 ? 981 ARG A NH1 1 ATOM 8069 N NH1 B ARG A 1 981 ? 48.349 45.887 -23.071 0.50 9.49 ? 981 ARG A NH1 1 ATOM 8070 N NH2 A ARG A 1 981 ? 45.698 43.849 -23.780 0.50 20.81 ? 981 ARG A NH2 1 ATOM 8071 N NH2 B ARG A 1 981 ? 49.608 44.649 -21.594 0.50 11.08 ? 981 ARG A NH2 1 ATOM 8072 N N . THR A 1 982 ? 44.149 49.731 -19.216 1.00 7.76 ? 982 THR A N 1 ATOM 8073 C CA . THR A 1 982 ? 42.715 49.905 -19.355 1.00 7.86 ? 982 THR A CA 1 ATOM 8074 C C . THR A 1 982 ? 42.166 48.874 -20.334 1.00 9.03 ? 982 THR A C 1 ATOM 8075 O O . THR A 1 982 ? 42.876 47.970 -20.725 1.00 10.71 ? 982 THR A O 1 ATOM 8076 C CB . THR A 1 982 ? 42.405 51.377 -19.700 1.00 8.12 ? 982 THR A CB 1 ATOM 8077 O OG1 . THR A 1 982 ? 41.001 51.613 -19.562 1.00 8.88 ? 982 THR A OG1 1 ATOM 8078 C CG2 . THR A 1 982 ? 42.804 51.741 -21.124 1.00 8.97 ? 982 THR A CG2 1 ATOM 8079 N N . ASN A 1 983 ? 40.884 48.944 -20.605 1.00 7.40 ? 983 ASN A N 1 ATOM 8080 C CA . ASN A 1 983 ? 40.314 48.073 -21.627 1.00 8.01 ? 983 ASN A CA 1 ATOM 8081 C C . ASN A 1 983 ? 39.591 48.949 -22.627 1.00 8.46 ? 983 ASN A C 1 ATOM 8082 O O . ASN A 1 983 ? 38.702 49.735 -22.257 1.00 8.87 ? 983 ASN A O 1 ATOM 8083 C CB . ASN A 1 983 ? 39.336 47.062 -21.025 1.00 7.28 ? 983 ASN A CB 1 ATOM 8084 C CG . ASN A 1 983 ? 38.827 46.103 -22.056 1.00 8.66 ? 983 ASN A CG 1 ATOM 8085 O OD1 . ASN A 1 983 ? 39.542 45.203 -22.461 1.00 9.60 ? 983 ASN A OD1 1 ATOM 8086 N ND2 . ASN A 1 983 ? 37.611 46.320 -22.520 1.00 9.57 ? 983 ASN A ND2 1 ATOM 8087 N N . LEU A 1 984 ? 40.031 48.843 -23.869 1.00 9.18 ? 984 LEU A N 1 ATOM 8088 C CA . LEU A 1 984 ? 39.457 49.651 -24.940 1.00 10.12 ? 984 LEU A CA 1 ATOM 8089 C C . LEU A 1 984 ? 38.607 48.789 -25.841 1.00 12.44 ? 984 LEU A C 1 ATOM 8090 O O . LEU A 1 984 ? 38.903 47.606 -26.031 1.00 11.99 ? 984 LEU A O 1 ATOM 8091 C CB . LEU A 1 984 ? 40.569 50.280 -25.768 1.00 9.51 ? 984 LEU A CB 1 ATOM 8092 C CG . LEU A 1 984 ? 41.516 51.158 -24.943 1.00 10.27 ? 984 LEU A CG 1 ATOM 8093 C CD1 . LEU A 1 984 ? 42.715 51.602 -25.824 1.00 12.41 ? 984 LEU A CD1 1 ATOM 8094 C CD2 . LEU A 1 984 ? 40.777 52.310 -24.239 1.00 9.79 ? 984 LEU A CD2 1 ATOM 8095 N N A MET A 1 985 ? 37.562 49.373 -26.386 0.50 13.63 ? 985 MET A N 1 ATOM 8096 N N B MET A 1 985 ? 37.552 49.374 -26.382 0.50 13.32 ? 985 MET A N 1 ATOM 8097 C CA A MET A 1 985 ? 36.696 48.664 -27.311 0.50 16.20 ? 985 MET A CA 1 ATOM 8098 C CA B MET A 1 985 ? 36.676 48.688 -27.332 0.50 15.47 ? 985 MET A CA 1 ATOM 8099 C C A MET A 1 985 ? 37.384 48.270 -28.578 0.50 17.02 ? 985 MET A C 1 ATOM 8100 C C B MET A 1 985 ? 37.395 48.266 -28.574 0.50 16.74 ? 985 MET A C 1 ATOM 8101 O O A MET A 1 985 ? 38.144 49.018 -29.141 0.50 17.22 ? 985 MET A O 1 ATOM 8102 O O B MET A 1 985 ? 38.162 49.006 -29.136 0.50 17.01 ? 985 MET A O 1 ATOM 8103 C CB A MET A 1 985 ? 35.517 49.532 -27.647 0.50 16.24 ? 985 MET A CB 1 ATOM 8104 C CB B MET A 1 985 ? 35.576 49.618 -27.783 0.50 15.65 ? 985 MET A CB 1 ATOM 8105 C CG A MET A 1 985 ? 34.625 49.711 -26.488 0.50 17.20 ? 985 MET A CG 1 ATOM 8106 C CG B MET A 1 985 ? 34.650 50.036 -26.720 0.50 16.08 ? 985 MET A CG 1 ATOM 8107 S SD A MET A 1 985 ? 32.968 49.348 -27.011 0.50 18.31 ? 985 MET A SD 1 ATOM 8108 S SD B MET A 1 985 ? 33.024 49.327 -26.982 0.50 17.41 ? 985 MET A SD 1 ATOM 8109 C CE A MET A 1 985 ? 32.785 50.768 -28.039 0.50 18.57 ? 985 MET A CE 1 ATOM 8110 C CE B MET A 1 985 ? 33.283 48.056 -25.754 0.50 11.97 ? 985 MET A CE 1 ATOM 8111 N N . GLN A 1 986 ? 37.094 47.058 -29.015 1.00 17.63 ? 986 GLN A N 1 ATOM 8112 C CA . GLN A 1 986 ? 37.587 46.545 -30.299 1.00 19.45 ? 986 GLN A CA 1 ATOM 8113 C C . GLN A 1 986 ? 36.597 47.014 -31.329 1.00 20.32 ? 986 GLN A C 1 ATOM 8114 O O . GLN A 1 986 ? 35.427 46.642 -31.247 1.00 19.67 ? 986 GLN A O 1 ATOM 8115 C CB . GLN A 1 986 ? 37.542 45.008 -30.306 1.00 21.04 ? 986 GLN A CB 1 ATOM 8116 C CG . GLN A 1 986 ? 38.466 44.309 -29.348 1.00 25.13 ? 986 GLN A CG 1 ATOM 8117 C CD . GLN A 1 986 ? 39.885 44.252 -29.844 1.00 29.93 ? 986 GLN A CD 1 ATOM 8118 O OE1 . GLN A 1 986 ? 40.138 44.213 -31.063 1.00 33.50 ? 986 GLN A OE1 1 ATOM 8119 N NE2 . GLN A 1 986 ? 40.824 44.245 -28.914 1.00 31.73 ? 986 GLN A NE2 1 ATOM 8120 N N . CYS A 1 987 ? 37.047 47.835 -32.286 1.00 20.52 ? 987 CYS A N 1 ATOM 8121 C CA . CYS A 1 987 ? 36.144 48.340 -33.320 1.00 23.61 ? 987 CYS A CA 1 ATOM 8122 C C . CYS A 1 987 ? 36.648 48.059 -34.739 1.00 24.62 ? 987 CYS A C 1 ATOM 8123 O O . CYS A 1 987 ? 36.278 48.771 -35.675 1.00 25.50 ? 987 CYS A O 1 ATOM 8124 C CB . CYS A 1 987 ? 35.861 49.832 -33.110 1.00 23.54 ? 987 CYS A CB 1 ATOM 8125 S SG . CYS A 1 987 ? 35.125 50.198 -31.492 1.00 26.96 ? 987 CYS A SG 1 ATOM 8126 N N . GLY A 1 988 ? 37.486 47.038 -34.892 1.00 26.23 ? 988 GLY A N 1 ATOM 8127 C CA . GLY A 1 988 ? 37.945 46.634 -36.211 1.00 29.18 ? 988 GLY A CA 1 ATOM 8128 C C . GLY A 1 988 ? 39.169 47.345 -36.749 1.00 31.35 ? 988 GLY A C 1 ATOM 8129 O O . GLY A 1 988 ? 39.540 47.139 -37.918 1.00 31.52 ? 988 GLY A O 1 ATOM 8130 N N . THR A 1 989 ? 39.811 48.163 -35.916 1.00 32.73 ? 989 THR A N 1 ATOM 8131 C CA . THR A 1 989 ? 41.070 48.796 -36.304 1.00 34.67 ? 989 THR A CA 1 ATOM 8132 C C . THR A 1 989 ? 42.210 47.845 -35.994 1.00 36.02 ? 989 THR A C 1 ATOM 8133 O O . THR A 1 989 ? 42.391 47.446 -34.842 1.00 36.26 ? 989 THR A O 1 ATOM 8134 C CB . THR A 1 989 ? 41.282 50.128 -35.575 1.00 34.51 ? 989 THR A CB 1 ATOM 8135 O OG1 . THR A 1 989 ? 40.158 50.981 -35.811 1.00 35.25 ? 989 THR A OG1 1 ATOM 8136 C CG2 . THR A 1 989 ? 42.451 50.893 -36.189 1.00 34.63 ? 989 THR A CG2 1 ATOM 8137 N N . PRO A 1 990 ? 42.963 47.458 -37.022 1.00 37.29 ? 990 PRO A N 1 ATOM 8138 C CA . PRO A 1 990 ? 44.109 46.562 -36.830 1.00 38.28 ? 990 PRO A CA 1 ATOM 8139 C C . PRO A 1 990 ? 45.151 47.095 -35.822 1.00 39.24 ? 990 PRO A C 1 ATOM 8140 O O . PRO A 1 990 ? 45.635 46.280 -35.026 1.00 39.60 ? 990 PRO A O 1 ATOM 8141 C CB . PRO A 1 990 ? 44.678 46.424 -38.245 1.00 38.50 ? 990 PRO A CB 1 ATOM 8142 C CG . PRO A 1 990 ? 43.486 46.666 -39.127 1.00 37.96 ? 990 PRO A CG 1 ATOM 8143 C CD . PRO A 1 990 ? 42.772 47.810 -38.443 1.00 37.45 ? 990 PRO A CD 1 ATOM 8144 N N . GLU A 1 991 ? 45.442 48.404 -35.826 1.00 40.13 ? 991 GLU A N 1 ATOM 8145 C CA . GLU A 1 991 ? 46.416 49.040 -34.905 1.00 41.13 ? 991 GLU A CA 1 ATOM 8146 C C . GLU A 1 991 ? 47.370 48.047 -34.200 1.00 41.04 ? 991 GLU A C 1 ATOM 8147 O O . GLU A 1 991 ? 47.147 47.697 -33.039 1.00 41.79 ? 991 GLU A O 1 ATOM 8148 C CB . GLU A 1 991 ? 45.680 49.893 -33.849 1.00 41.19 ? 991 GLU A CB 1 ATOM 8149 C CG . GLU A 1 991 ? 45.619 51.393 -34.133 1.00 41.94 ? 991 GLU A CG 1 ATOM 8150 C CD . GLU A 1 991 ? 44.654 52.150 -33.212 1.00 42.38 ? 991 GLU A CD 1 ATOM 8151 O OE1 . GLU A 1 991 ? 44.108 51.549 -32.248 1.00 43.43 ? 991 GLU A OE1 1 ATOM 8152 O OE2 . GLU A 1 991 ? 44.427 53.360 -33.455 1.00 43.25 ? 991 GLU A OE2 1 ATOM 8153 N N . GLU A 1 992 ? 48.425 47.599 -34.886 1.00 40.48 ? 992 GLU A N 1 ATOM 8154 C CA . GLU A 1 992 ? 49.168 46.407 -34.426 1.00 40.22 ? 992 GLU A CA 1 ATOM 8155 C C . GLU A 1 992 ? 50.557 46.578 -33.755 1.00 39.08 ? 992 GLU A C 1 ATOM 8156 O O . GLU A 1 992 ? 50.620 46.931 -32.580 1.00 39.19 ? 992 GLU A O 1 ATOM 8157 C CB . GLU A 1 992 ? 49.180 45.322 -35.515 1.00 40.78 ? 992 GLU A CB 1 ATOM 8158 C CG . GLU A 1 992 ? 48.015 44.350 -35.380 1.00 42.33 ? 992 GLU A CG 1 ATOM 8159 C CD . GLU A 1 992 ? 47.554 43.770 -36.704 1.00 44.81 ? 992 GLU A CD 1 ATOM 8160 O OE1 . GLU A 1 992 ? 47.263 44.552 -37.635 1.00 46.62 ? 992 GLU A OE1 1 ATOM 8161 O OE2 . GLU A 1 992 ? 47.464 42.527 -36.809 1.00 46.39 ? 992 GLU A OE2 1 ATOM 8162 N N . HIS A 1 993 ? 51.641 46.306 -34.489 1.00 37.59 ? 993 HIS A N 1 ATOM 8163 C CA . HIS A 1 993 ? 53.029 46.291 -33.962 1.00 36.03 ? 993 HIS A CA 1 ATOM 8164 C C . HIS A 1 993 ? 53.372 47.284 -32.825 1.00 33.99 ? 993 HIS A C 1 ATOM 8165 O O . HIS A 1 993 ? 53.483 48.496 -33.075 1.00 34.08 ? 993 HIS A O 1 ATOM 8166 C CB . HIS A 1 993 ? 53.998 46.559 -35.123 1.00 37.00 ? 993 HIS A CB 1 ATOM 8167 C CG . HIS A 1 993 ? 53.869 47.940 -35.693 1.00 38.07 ? 993 HIS A CG 1 ATOM 8168 N ND1 . HIS A 1 993 ? 54.580 49.014 -35.203 1.00 40.33 ? 993 HIS A ND1 1 ATOM 8169 C CD2 . HIS A 1 993 ? 53.067 48.433 -36.666 1.00 40.54 ? 993 HIS A CD2 1 ATOM 8170 C CE1 . HIS A 1 993 ? 54.242 50.105 -35.866 1.00 40.26 ? 993 HIS A CE1 1 ATOM 8171 N NE2 . HIS A 1 993 ? 53.326 49.780 -36.761 1.00 41.54 ? 993 HIS A NE2 1 ATOM 8172 N N . THR A 1 994 ? 53.541 46.792 -31.591 1.00 30.97 ? 994 THR A N 1 ATOM 8173 C CA . THR A 1 994 ? 54.142 47.621 -30.519 1.00 28.14 ? 994 THR A CA 1 ATOM 8174 C C . THR A 1 994 ? 55.198 46.857 -29.715 1.00 26.24 ? 994 THR A C 1 ATOM 8175 O O . THR A 1 994 ? 55.276 45.632 -29.782 1.00 27.12 ? 994 THR A O 1 ATOM 8176 C CB . THR A 1 994 ? 53.082 48.236 -29.540 1.00 27.93 ? 994 THR A CB 1 ATOM 8177 O OG1 . THR A 1 994 ? 52.256 47.199 -28.997 1.00 26.92 ? 994 THR A OG1 1 ATOM 8178 C CG2 . THR A 1 994 ? 52.107 49.187 -30.258 1.00 27.20 ? 994 THR A CG2 1 ATOM 8179 N N . GLN A 1 995 ? 55.968 47.582 -28.907 1.00 23.39 ? 995 GLN A N 1 ATOM 8180 C CA . GLN A 1 995 ? 57.022 46.965 -28.122 1.00 21.49 ? 995 GLN A CA 1 ATOM 8181 C C . GLN A 1 995 ? 56.560 46.620 -26.711 1.00 19.58 ? 995 GLN A C 1 ATOM 8182 O O . GLN A 1 995 ? 55.787 47.368 -26.089 1.00 18.85 ? 995 GLN A O 1 ATOM 8183 C CB . GLN A 1 995 ? 58.229 47.887 -28.047 1.00 21.51 ? 995 GLN A CB 1 ATOM 8184 C CG . GLN A 1 995 ? 58.796 48.266 -29.407 1.00 23.69 ? 995 GLN A CG 1 ATOM 8185 C CD . GLN A 1 995 ? 59.598 49.548 -29.367 1.00 28.32 ? 995 GLN A CD 1 ATOM 8186 O OE1 . GLN A 1 995 ? 59.058 50.623 -29.088 1.00 22.08 ? 995 GLN A OE1 1 ATOM 8187 N NE2 . GLN A 1 995 ? 60.892 49.444 -29.665 1.00 30.85 ? 995 GLN A NE2 1 ATOM 8188 N N . LYS A 1 996 ? 57.045 45.490 -26.206 1.00 18.00 ? 996 LYS A N 1 ATOM 8189 C CA . LYS A 1 996 ? 56.841 45.124 -24.819 1.00 17.95 ? 996 LYS A CA 1 ATOM 8190 C C . LYS A 1 996 ? 57.519 46.139 -23.926 1.00 16.85 ? 996 LYS A C 1 ATOM 8191 O O . LYS A 1 996 ? 58.656 46.535 -24.156 1.00 17.06 ? 996 LYS A O 1 ATOM 8192 C CB . LYS A 1 996 ? 57.438 43.735 -24.553 1.00 19.00 ? 996 LYS A CB 1 ATOM 8193 C CG . LYS A 1 996 ? 56.576 42.615 -25.065 1.00 22.62 ? 996 LYS A CG 1 ATOM 8194 C CD . LYS A 1 996 ? 55.161 42.723 -24.502 1.00 28.26 ? 996 LYS A CD 1 ATOM 8195 C CE . LYS A 1 996 ? 54.437 41.399 -24.592 1.00 29.46 ? 996 LYS A CE 1 ATOM 8196 N NZ . LYS A 1 996 ? 54.166 41.045 -26.013 1.00 32.09 ? 996 LYS A NZ 1 ATOM 8197 N N . LEU A 1 997 ? 56.793 46.572 -22.907 1.00 15.34 ? 997 LEU A N 1 ATOM 8198 C CA . LEU A 1 997 ? 57.376 47.410 -21.889 1.00 15.38 ? 997 LEU A CA 1 ATOM 8199 C C . LEU A 1 997 ? 57.722 46.553 -20.681 1.00 14.64 ? 997 LEU A C 1 ATOM 8200 O O . LEU A 1 997 ? 56.834 45.960 -20.050 1.00 15.76 ? 997 LEU A O 1 ATOM 8201 C CB . LEU A 1 997 ? 56.393 48.522 -21.503 1.00 16.57 ? 997 LEU A CB 1 ATOM 8202 C CG . LEU A 1 997 ? 56.808 49.356 -20.291 1.00 17.60 ? 997 LEU A CG 1 ATOM 8203 C CD1 . LEU A 1 997 ? 58.021 50.246 -20.576 1.00 20.47 ? 997 LEU A CD1 1 ATOM 8204 C CD2 . LEU A 1 997 ? 55.621 50.172 -19.871 1.00 19.05 ? 997 LEU A CD2 1 ATOM 8205 N N . ASP A 1 998 ? 59.010 46.509 -20.366 1.00 13.94 ? 998 ASP A N 1 ATOM 8206 C CA . ASP A 1 998 ? 59.506 45.887 -19.147 1.00 13.84 ? 998 ASP A CA 1 ATOM 8207 C C . ASP A 1 998 ? 60.077 46.973 -18.259 1.00 13.70 ? 998 ASP A C 1 ATOM 8208 O O . ASP A 1 998 ? 61.215 47.439 -18.435 1.00 13.50 ? 998 ASP A O 1 ATOM 8209 C CB . ASP A 1 998 ? 60.562 44.822 -19.493 1.00 14.20 ? 998 ASP A CB 1 ATOM 8210 C CG . ASP A 1 998 ? 61.266 44.287 -18.277 1.00 16.57 ? 998 ASP A CG 1 ATOM 8211 O OD1 . ASP A 1 998 ? 60.792 44.516 -17.136 1.00 16.23 ? 998 ASP A OD1 1 ATOM 8212 O OD2 . ASP A 1 998 ? 62.328 43.622 -18.398 1.00 17.90 ? 998 ASP A OD2 1 ATOM 8213 N N . VAL A 1 999 ? 59.277 47.401 -17.280 1.00 13.26 ? 999 VAL A N 1 ATOM 8214 C CA . VAL A 1 999 ? 59.722 48.523 -16.474 1.00 12.36 ? 999 VAL A CA 1 ATOM 8215 C C . VAL A 1 999 ? 60.995 48.239 -15.687 1.00 13.13 ? 999 VAL A C 1 ATOM 8216 O O . VAL A 1 999 ? 61.754 49.142 -15.362 1.00 12.73 ? 999 VAL A O 1 ATOM 8217 C CB . VAL A 1 999 ? 58.633 49.041 -15.516 1.00 12.45 ? 999 VAL A CB 1 ATOM 8218 C CG1 . VAL A 1 999 ? 57.500 49.660 -16.317 1.00 12.12 ? 999 VAL A CG1 1 ATOM 8219 C CG2 . VAL A 1 999 ? 58.146 47.939 -14.553 1.00 12.24 ? 999 VAL A CG2 1 ATOM 8220 N N . CYS A 1 1000 ? 61.249 46.968 -15.398 1.00 13.49 ? 1000 CYS A N 1 ATOM 8221 C CA . CYS A 1 1000 ? 62.448 46.653 -14.630 1.00 15.54 ? 1000 CYS A CA 1 ATOM 8222 C C . CYS A 1 1000 ? 63.781 46.884 -15.356 1.00 14.85 ? 1000 CYS A C 1 ATOM 8223 O O . CYS A 1 1000 ? 64.807 47.007 -14.712 1.00 16.84 ? 1000 CYS A O 1 ATOM 8224 C CB . CYS A 1 1000 ? 62.348 45.244 -14.037 1.00 15.97 ? 1000 CYS A CB 1 ATOM 8225 S SG . CYS A 1 1000 ? 61.297 45.214 -12.543 1.00 18.95 ? 1000 CYS A SG 1 ATOM 8226 N N . HIS A 1 1001 ? 63.728 47.027 -16.681 1.00 15.03 ? 1001 HIS A N 1 ATOM 8227 C CA . HIS A 1 1001 ? 64.935 47.295 -17.467 1.00 15.74 ? 1001 HIS A CA 1 ATOM 8228 C C . HIS A 1 1001 ? 64.983 48.733 -18.014 1.00 16.38 ? 1001 HIS A C 1 ATOM 8229 O O . HIS A 1 1001 ? 65.770 49.063 -18.907 1.00 16.70 ? 1001 HIS A O 1 ATOM 8230 C CB . HIS A 1 1001 ? 65.094 46.238 -18.572 1.00 16.30 ? 1001 HIS A CB 1 ATOM 8231 C CG . HIS A 1 1001 ? 65.661 44.941 -18.085 1.00 17.74 ? 1001 HIS A CG 1 ATOM 8232 N ND1 . HIS A 1 1001 ? 64.871 43.873 -17.729 1.00 18.34 ? 1001 HIS A ND1 1 ATOM 8233 C CD2 . HIS A 1 1001 ? 66.943 44.547 -17.888 1.00 19.92 ? 1001 HIS A CD2 1 ATOM 8234 C CE1 . HIS A 1 1001 ? 65.639 42.868 -17.339 1.00 19.70 ? 1001 HIS A CE1 1 ATOM 8235 N NE2 . HIS A 1 1001 ? 66.902 43.252 -17.426 1.00 20.87 ? 1001 HIS A NE2 1 ATOM 8236 N N . LEU A 1 1002 ? 64.141 49.604 -17.475 1.00 15.41 ? 1002 LEU A N 1 ATOM 8237 C CA . LEU A 1 1002 ? 64.186 50.998 -17.883 1.00 15.97 ? 1002 LEU A CA 1 ATOM 8238 C C . LEU A 1 1002 ? 65.435 51.688 -17.358 1.00 16.25 ? 1002 LEU A C 1 ATOM 8239 O O . LEU A 1 1002 ? 65.924 52.657 -17.967 1.00 17.11 ? 1002 LEU A O 1 ATOM 8240 C CB . LEU A 1 1002 ? 62.945 51.750 -17.406 1.00 15.69 ? 1002 LEU A CB 1 ATOM 8241 C CG . LEU A 1 1002 ? 61.737 51.552 -18.291 1.00 15.29 ? 1002 LEU A CG 1 ATOM 8242 C CD1 . LEU A 1 1002 ? 60.510 52.134 -17.612 1.00 14.74 ? 1002 LEU A CD1 1 ATOM 8243 C CD2 . LEU A 1 1002 ? 61.932 52.237 -19.635 1.00 15.93 ? 1002 LEU A CD2 1 ATOM 8244 N N . LEU A 1 1003 ? 65.934 51.240 -16.211 1.00 16.60 ? 1003 LEU A N 1 ATOM 8245 C CA . LEU A 1 1003 ? 67.157 51.786 -15.628 1.00 17.39 ? 1003 LEU A CA 1 ATOM 8246 C C . LEU A 1 1003 ? 68.235 50.703 -15.704 1.00 18.23 ? 1003 LEU A C 1 ATOM 8247 O O . LEU A 1 1003 ? 67.939 49.509 -15.614 1.00 18.48 ? 1003 LEU A O 1 ATOM 8248 C CB . LEU A 1 1003 ? 66.942 52.224 -14.181 1.00 17.53 ? 1003 LEU A CB 1 ATOM 8249 C CG . LEU A 1 1003 ? 66.252 53.575 -13.948 1.00 19.83 ? 1003 LEU A CG 1 ATOM 8250 C CD1 . LEU A 1 1003 ? 64.810 53.612 -14.404 1.00 25.60 ? 1003 LEU A CD1 1 ATOM 8251 C CD2 . LEU A 1 1003 ? 66.309 53.913 -12.494 1.00 24.51 ? 1003 LEU A CD2 1 ATOM 8252 N N . PRO A 1 1004 ? 69.487 51.107 -15.884 1.00 18.87 ? 1004 PRO A N 1 ATOM 8253 C CA . PRO A 1 1004 ? 70.555 50.125 -16.074 1.00 18.73 ? 1004 PRO A CA 1 ATOM 8254 C C . PRO A 1 1004 ? 70.934 49.408 -14.772 1.00 18.84 ? 1004 PRO A C 1 ATOM 8255 O O . PRO A 1 1004 ? 70.486 49.759 -13.663 1.00 17.15 ? 1004 PRO A O 1 ATOM 8256 C CB . PRO A 1 1004 ? 71.705 50.983 -16.620 1.00 19.23 ? 1004 PRO A CB 1 ATOM 8257 C CG . PRO A 1 1004 ? 71.474 52.316 -16.028 1.00 19.73 ? 1004 PRO A CG 1 ATOM 8258 C CD . PRO A 1 1004 ? 69.984 52.495 -15.930 1.00 19.06 ? 1004 PRO A CD 1 ATOM 8259 N N . ASN A 1 1005 ? 71.749 48.365 -14.917 1.00 18.96 ? 1005 ASN A N 1 ATOM 8260 C CA . ASN A 1 1005 ? 72.276 47.601 -13.787 1.00 19.57 ? 1005 ASN A CA 1 ATOM 8261 C C . ASN A 1 1005 ? 71.205 47.003 -12.858 1.00 18.64 ? 1005 ASN A C 1 ATOM 8262 O O . ASN A 1 1005 ? 71.357 47.032 -11.636 1.00 18.87 ? 1005 ASN A O 1 ATOM 8263 C CB . ASN A 1 1005 ? 73.245 48.452 -12.957 1.00 20.83 ? 1005 ASN A CB 1 ATOM 8264 C CG . ASN A 1 1005 ? 74.291 49.148 -13.806 1.00 24.01 ? 1005 ASN A CG 1 ATOM 8265 O OD1 . ASN A 1 1005 ? 74.436 50.374 -13.748 1.00 29.22 ? 1005 ASN A OD1 1 ATOM 8266 N ND2 . ASN A 1 1005 ? 75.012 48.375 -14.608 1.00 25.65 ? 1005 ASN A ND2 1 ATOM 8267 N N . VAL A 1 1006 ? 70.141 46.457 -13.442 1.00 18.44 ? 1006 VAL A N 1 ATOM 8268 C CA . VAL A 1 1006 ? 69.082 45.855 -12.617 1.00 17.99 ? 1006 VAL A CA 1 ATOM 8269 C C . VAL A 1 1006 ? 69.636 44.578 -11.984 1.00 18.44 ? 1006 VAL A C 1 ATOM 8270 O O . VAL A 1 1006 ? 70.320 43.810 -12.649 1.00 19.29 ? 1006 VAL A O 1 ATOM 8271 C CB . VAL A 1 1006 ? 67.751 45.627 -13.411 1.00 18.40 ? 1006 VAL A CB 1 ATOM 8272 C CG1 . VAL A 1 1006 ? 67.932 44.679 -14.568 1.00 17.80 ? 1006 VAL A CG1 1 ATOM 8273 C CG2 . VAL A 1 1006 ? 66.609 45.150 -12.477 1.00 16.88 ? 1006 VAL A CG2 1 ATOM 8274 N N . ALA A 1 1007 ? 69.369 44.397 -10.694 1.00 16.71 ? 1007 ALA A N 1 ATOM 8275 C CA . ALA A 1 1007 ? 69.831 43.234 -9.930 1.00 17.03 ? 1007 ALA A CA 1 ATOM 8276 C C . ALA A 1 1007 ? 68.663 42.381 -9.459 1.00 17.17 ? 1007 ALA A C 1 ATOM 8277 O O . ALA A 1 1007 ? 68.852 41.215 -9.094 1.00 18.42 ? 1007 ALA A O 1 ATOM 8278 C CB . ALA A 1 1007 ? 70.650 43.697 -8.737 1.00 16.94 ? 1007 ALA A CB 1 ATOM 8279 N N . ARG A 1 1008 ? 67.451 42.953 -9.436 1.00 15.92 ? 1008 ARG A N 1 ATOM 8280 C CA . ARG A 1 1008 ? 66.269 42.233 -8.965 1.00 15.74 ? 1008 ARG A CA 1 ATOM 8281 C C . ARG A 1 1008 ? 65.032 42.967 -9.448 1.00 15.11 ? 1008 ARG A C 1 ATOM 8282 O O . ARG A 1 1008 ? 65.061 44.182 -9.599 1.00 13.47 ? 1008 ARG A O 1 ATOM 8283 C CB . ARG A 1 1008 ? 66.260 42.207 -7.445 1.00 16.14 ? 1008 ARG A CB 1 ATOM 8284 C CG . ARG A 1 1008 ? 65.242 41.296 -6.824 1.00 19.77 ? 1008 ARG A CG 1 ATOM 8285 C CD . ARG A 1 1008 ? 65.347 41.303 -5.316 1.00 22.99 ? 1008 ARG A CD 1 ATOM 8286 N NE . ARG A 1 1008 ? 64.581 40.215 -4.716 1.00 29.45 ? 1008 ARG A NE 1 ATOM 8287 C CZ . ARG A 1 1008 ? 65.042 38.981 -4.516 1.00 31.91 ? 1008 ARG A CZ 1 ATOM 8288 N NH1 . ARG A 1 1008 ? 66.285 38.659 -4.862 1.00 31.32 ? 1008 ARG A NH1 1 ATOM 8289 N NH2 . ARG A 1 1008 ? 64.250 38.064 -3.966 1.00 33.21 ? 1008 ARG A NH2 1 ATOM 8290 N N . CYS A 1 1009 ? 63.976 42.212 -9.712 1.00 14.03 ? 1009 CYS A N 1 ATOM 8291 C CA . CYS A 1 1009 ? 62.663 42.775 -10.062 1.00 13.90 ? 1009 CYS A CA 1 ATOM 8292 C C . CYS A 1 1009 ? 61.653 42.033 -9.221 1.00 13.40 ? 1009 CYS A C 1 ATOM 8293 O O . CYS A 1 1009 ? 61.617 40.797 -9.227 1.00 13.48 ? 1009 CYS A O 1 ATOM 8294 C CB . CYS A 1 1009 ? 62.374 42.542 -11.540 1.00 14.76 ? 1009 CYS A CB 1 ATOM 8295 S SG . CYS A 1 1009 ? 60.850 43.288 -12.174 1.00 18.68 ? 1009 CYS A SG 1 ATOM 8296 N N . GLU A 1 1010 ? 60.830 42.783 -8.489 1.00 11.24 ? 1010 GLU A N 1 ATOM 8297 C CA . GLU A 1 1010 ? 59.803 42.183 -7.663 1.00 11.21 ? 1010 GLU A CA 1 ATOM 8298 C C . GLU A 1 1010 ? 58.429 42.772 -7.978 1.00 10.26 ? 1010 GLU A C 1 ATOM 8299 O O . GLU A 1 1010 ? 58.317 43.976 -8.189 1.00 10.81 ? 1010 GLU A O 1 ATOM 8300 C CB . GLU A 1 1010 ? 60.110 42.429 -6.193 1.00 12.25 ? 1010 GLU A CB 1 ATOM 8301 C CG . GLU A 1 1010 ? 61.276 41.564 -5.717 1.00 17.21 ? 1010 GLU A CG 1 ATOM 8302 C CD . GLU A 1 1010 ? 62.099 42.175 -4.596 1.00 22.23 ? 1010 GLU A CD 1 ATOM 8303 O OE1 . GLU A 1 1010 ? 62.467 43.379 -4.643 1.00 24.36 ? 1010 GLU A OE1 1 ATOM 8304 O OE2 . GLU A 1 1010 ? 62.412 41.410 -3.651 1.00 25.54 ? 1010 GLU A OE2 1 ATOM 8305 N N . ARG A 1 1011 ? 57.405 41.942 -7.950 1.00 8.55 ? 1011 ARG A N 1 ATOM 8306 C CA . ARG A 1 1011 ? 56.032 42.460 -7.953 1.00 8.93 ? 1011 ARG A CA 1 ATOM 8307 C C . ARG A 1 1011 ? 55.692 42.781 -6.510 1.00 8.99 ? 1011 ARG A C 1 ATOM 8308 O O . ARG A 1 1011 ? 56.011 42.000 -5.616 1.00 8.81 ? 1011 ARG A O 1 ATOM 8309 C CB . ARG A 1 1011 ? 55.073 41.443 -8.589 1.00 10.47 ? 1011 ARG A CB 1 ATOM 8310 C CG . ARG A 1 1011 ? 53.701 42.043 -8.902 1.00 12.63 ? 1011 ARG A CG 1 ATOM 8311 C CD . ARG A 1 1011 ? 52.758 41.089 -9.570 1.00 12.43 ? 1011 ARG A CD 1 ATOM 8312 N NE . ARG A 1 1011 ? 52.475 39.961 -8.698 1.00 20.15 ? 1011 ARG A NE 1 ATOM 8313 C CZ . ARG A 1 1011 ? 51.516 39.951 -7.772 1.00 24.08 ? 1011 ARG A CZ 1 ATOM 8314 N NH1 . ARG A 1 1011 ? 50.746 41.022 -7.590 1.00 27.28 ? 1011 ARG A NH1 1 ATOM 8315 N NH2 . ARG A 1 1011 ? 51.325 38.870 -7.023 1.00 25.69 ? 1011 ARG A NH2 1 ATOM 8316 N N . THR A 1 1012 ? 55.062 43.931 -6.270 1.00 6.89 ? 1012 THR A N 1 ATOM 8317 C CA . THR A 1 1012 ? 54.733 44.356 -4.924 1.00 6.78 ? 1012 THR A CA 1 ATOM 8318 C C . THR A 1 1012 ? 53.266 44.742 -4.826 1.00 6.47 ? 1012 THR A C 1 ATOM 8319 O O . THR A 1 1012 ? 52.601 44.938 -5.855 1.00 7.35 ? 1012 THR A O 1 ATOM 8320 C CB . THR A 1 1012 ? 55.599 45.580 -4.499 1.00 8.05 ? 1012 THR A CB 1 ATOM 8321 O OG1 . THR A 1 1012 ? 55.294 46.711 -5.340 1.00 9.23 ? 1012 THR A OG1 1 ATOM 8322 C CG2 . THR A 1 1012 ? 57.074 45.364 -4.708 1.00 7.95 ? 1012 THR A CG2 1 ATOM 8323 N N . THR A 1 1013 ? 52.816 44.991 -3.599 1.00 6.18 ? 1013 THR A N 1 ATOM 8324 C CA . THR A 1 1013 ? 51.564 45.702 -3.416 1.00 6.20 ? 1013 THR A CA 1 ATOM 8325 C C . THR A 1 1013 ? 51.668 47.113 -4.054 1.00 5.95 ? 1013 THR A C 1 ATOM 8326 O O . THR A 1 1013 ? 52.741 47.625 -4.314 1.00 6.34 ? 1013 THR A O 1 ATOM 8327 C CB . THR A 1 1013 ? 51.232 45.825 -1.942 1.00 7.24 ? 1013 THR A CB 1 ATOM 8328 O OG1 . THR A 1 1013 ? 52.399 46.264 -1.220 1.00 8.00 ? 1013 THR A OG1 1 ATOM 8329 C CG2 . THR A 1 1013 ? 50.778 44.431 -1.351 1.00 8.37 ? 1013 THR A CG2 1 ATOM 8330 N N . LEU A 1 1014 ? 50.515 47.761 -4.255 1.00 5.79 ? 1014 LEU A N 1 ATOM 8331 C CA . LEU A 1 1014 ? 50.535 49.014 -5.022 1.00 5.81 ? 1014 LEU A CA 1 ATOM 8332 C C . LEU A 1 1014 ? 51.190 50.155 -4.305 1.00 5.31 ? 1014 LEU A C 1 ATOM 8333 O O . LEU A 1 1014 ? 51.551 51.153 -4.928 1.00 6.06 ? 1014 LEU A O 1 ATOM 8334 C CB . LEU A 1 1014 ? 49.123 49.424 -5.417 1.00 6.74 ? 1014 LEU A CB 1 ATOM 8335 C CG . LEU A 1 1014 ? 48.381 48.485 -6.348 1.00 5.62 ? 1014 LEU A CG 1 ATOM 8336 C CD1 . LEU A 1 1014 ? 47.036 49.194 -6.671 1.00 7.91 ? 1014 LEU A CD1 1 ATOM 8337 C CD2 . LEU A 1 1014 ? 49.158 48.149 -7.645 1.00 7.39 ? 1014 LEU A CD2 1 ATOM 8338 N N . THR A 1 1015 ? 51.350 49.998 -2.990 1.00 5.34 ? 1015 THR A N 1 ATOM 8339 C CA . THR A 1 1015 ? 52.017 50.984 -2.149 1.00 5.49 ? 1015 THR A CA 1 ATOM 8340 C C . THR A 1 1015 ? 53.526 50.749 -2.097 1.00 5.93 ? 1015 THR A C 1 ATOM 8341 O O . THR A 1 1015 ? 54.229 51.522 -1.430 1.00 7.03 ? 1015 THR A O 1 ATOM 8342 C CB . THR A 1 1015 ? 51.509 50.884 -0.721 1.00 6.28 ? 1015 THR A CB 1 ATOM 8343 O OG1 . THR A 1 1015 ? 51.636 49.498 -0.342 1.00 6.80 ? 1015 THR A OG1 1 ATOM 8344 C CG2 . THR A 1 1015 ? 50.018 51.218 -0.652 1.00 6.49 ? 1015 THR A CG2 1 ATOM 8345 N N . PHE A 1 1016 ? 53.988 49.673 -2.737 1.00 5.71 ? 1016 PHE A N 1 ATOM 8346 C CA . PHE A 1 1016 ? 55.395 49.264 -2.753 1.00 7.08 ? 1016 PHE A CA 1 ATOM 8347 C C . PHE A 1 1016 ? 55.862 48.670 -1.434 1.00 8.39 ? 1016 PHE A C 1 ATOM 8348 O O . PHE A 1 1016 ? 57.050 48.405 -1.292 1.00 9.93 ? 1016 PHE A O 1 ATOM 8349 C CB . PHE A 1 1016 ? 56.334 50.389 -3.192 1.00 7.75 ? 1016 PHE A CB 1 ATOM 8350 C CG . PHE A 1 1016 ? 55.980 51.026 -4.516 1.00 6.24 ? 1016 PHE A CG 1 ATOM 8351 C CD1 . PHE A 1 1016 ? 55.846 50.261 -5.669 1.00 7.08 ? 1016 PHE A CD1 1 ATOM 8352 C CD2 . PHE A 1 1016 ? 55.820 52.410 -4.605 1.00 7.51 ? 1016 PHE A CD2 1 ATOM 8353 C CE1 . PHE A 1 1016 ? 55.546 50.887 -6.898 1.00 6.66 ? 1016 PHE A CE1 1 ATOM 8354 C CE2 . PHE A 1 1016 ? 55.521 53.021 -5.825 1.00 7.54 ? 1016 PHE A CE2 1 ATOM 8355 C CZ . PHE A 1 1016 ? 55.407 52.243 -6.961 1.00 7.18 ? 1016 PHE A CZ 1 ATOM 8356 N N . LEU A 1 1017 ? 54.958 48.392 -0.509 1.00 7.19 ? 1017 LEU A N 1 ATOM 8357 C CA . LEU A 1 1017 ? 55.385 48.060 0.855 1.00 8.98 ? 1017 LEU A CA 1 ATOM 8358 C C . LEU A 1 1017 ? 55.564 46.571 1.131 1.00 9.75 ? 1017 LEU A C 1 ATOM 8359 O O . LEU A 1 1017 ? 56.149 46.213 2.174 1.00 12.01 ? 1017 LEU A O 1 ATOM 8360 C CB . LEU A 1 1017 ? 54.424 48.679 1.865 1.00 8.68 ? 1017 LEU A CB 1 ATOM 8361 C CG . LEU A 1 1017 ? 54.448 50.210 1.859 1.00 8.08 ? 1017 LEU A CG 1 ATOM 8362 C CD1 . LEU A 1 1017 ? 53.360 50.697 2.777 1.00 9.49 ? 1017 LEU A CD1 1 ATOM 8363 C CD2 . LEU A 1 1017 ? 55.780 50.813 2.217 1.00 10.06 ? 1017 LEU A CD2 1 ATOM 8364 N N . GLN A 1 1018 ? 55.095 45.693 0.246 1.00 8.88 ? 1018 GLN A N 1 ATOM 8365 C CA . GLN A 1 1018 ? 55.283 44.242 0.471 1.00 10.11 ? 1018 GLN A CA 1 ATOM 8366 C C . GLN A 1 1018 ? 55.651 43.577 -0.827 1.00 10.54 ? 1018 GLN A C 1 ATOM 8367 O O . GLN A 1 1018 ? 55.006 43.811 -1.845 1.00 10.06 ? 1018 GLN A O 1 ATOM 8368 C CB . GLN A 1 1018 ? 54.002 43.608 1.009 1.00 10.88 ? 1018 GLN A CB 1 ATOM 8369 C CG . GLN A 1 1018 ? 54.200 42.096 1.302 1.00 14.68 ? 1018 GLN A CG 1 ATOM 8370 C CD . GLN A 1 1018 ? 52.903 41.342 1.501 1.00 19.87 ? 1018 GLN A CD 1 ATOM 8371 O OE1 . GLN A 1 1018 ? 51.823 41.944 1.588 1.00 18.93 ? 1018 GLN A OE1 1 ATOM 8372 N NE2 . GLN A 1 1018 ? 53.004 40.009 1.589 1.00 22.42 ? 1018 GLN A NE2 1 ATOM 8373 N N . ASN A 1 1019 ? 56.701 42.767 -0.810 1.00 11.55 ? 1019 ASN A N 1 ATOM 8374 C CA . ASN A 1 1019 ? 57.073 41.981 -1.973 1.00 13.88 ? 1019 ASN A CA 1 ATOM 8375 C C . ASN A 1 1019 ? 56.178 40.780 -2.115 1.00 14.74 ? 1019 ASN A C 1 ATOM 8376 O O . ASN A 1 1019 ? 55.998 40.028 -1.141 1.00 16.25 ? 1019 ASN A O 1 ATOM 8377 C CB . ASN A 1 1019 ? 58.543 41.552 -1.855 1.00 14.04 ? 1019 ASN A CB 1 ATOM 8378 C CG . ASN A 1 1019 ? 59.486 42.753 -1.766 1.00 16.41 ? 1019 ASN A CG 1 ATOM 8379 O OD1 . ASN A 1 1019 ? 59.251 43.792 -2.394 1.00 16.51 ? 1019 ASN A OD1 1 ATOM 8380 N ND2 . ASN A 1 1019 ? 60.572 42.616 -0.985 1.00 19.91 ? 1019 ASN A ND2 1 ATOM 8381 N N . LEU A 1 1020 ? 55.614 40.603 -3.302 1.00 13.99 ? 1020 LEU A N 1 ATOM 8382 C CA . LEU A 1 1020 ? 54.679 39.525 -3.580 1.00 14.91 ? 1020 LEU A CA 1 ATOM 8383 C C . LEU A 1 1020 ? 55.271 38.423 -4.435 1.00 15.69 ? 1020 LEU A C 1 ATOM 8384 O O . LEU A 1 1020 ? 54.852 37.267 -4.302 1.00 16.71 ? 1020 LEU A O 1 ATOM 8385 C CB . LEU A 1 1020 ? 53.403 40.044 -4.259 1.00 15.08 ? 1020 LEU A CB 1 ATOM 8386 C CG . LEU A 1 1020 ? 52.601 41.109 -3.486 1.00 14.68 ? 1020 LEU A CG 1 ATOM 8387 C CD1 . LEU A 1 1020 ? 51.511 41.647 -4.377 1.00 17.23 ? 1020 LEU A CD1 1 ATOM 8388 C CD2 . LEU A 1 1020 ? 52.010 40.501 -2.222 1.00 16.36 ? 1020 LEU A CD2 1 ATOM 8389 N N . GLU A 1 1021 ? 56.231 38.760 -5.296 1.00 15.94 ? 1021 GLU A N 1 ATOM 8390 C CA . GLU A 1 1021 ? 56.820 37.783 -6.221 1.00 18.10 ? 1021 GLU A CA 1 ATOM 8391 C C . GLU A 1 1021 ? 58.189 38.235 -6.655 1.00 17.29 ? 1021 GLU A C 1 ATOM 8392 O O . GLU A 1 1021 ? 58.389 39.395 -6.967 1.00 15.41 ? 1021 GLU A O 1 ATOM 8393 C CB . GLU A 1 1021 ? 55.932 37.650 -7.459 1.00 17.75 ? 1021 GLU A CB 1 ATOM 8394 C CG . GLU A 1 1021 ? 56.279 36.536 -8.442 1.00 22.26 ? 1021 GLU A CG 1 ATOM 8395 C CD . GLU A 1 1021 ? 55.421 36.576 -9.698 1.00 23.27 ? 1021 GLU A CD 1 ATOM 8396 O OE1 . GLU A 1 1021 ? 54.473 37.404 -9.769 1.00 29.61 ? 1021 GLU A OE1 1 ATOM 8397 O OE2 . GLU A 1 1021 ? 55.703 35.776 -10.628 1.00 28.59 ? 1021 GLU A OE2 1 ATOM 8398 N N . HIS A 1 1022 ? 59.135 37.304 -6.716 1.00 17.37 ? 1022 HIS A N 1 ATOM 8399 C CA . HIS A 1 1022 ? 60.470 37.580 -7.194 1.00 18.29 ? 1022 HIS A CA 1 ATOM 8400 C C . HIS A 1 1022 ? 60.486 37.141 -8.636 1.00 18.19 ? 1022 HIS A C 1 ATOM 8401 O O . HIS A 1 1022 ? 60.209 35.977 -8.931 1.00 18.79 ? 1022 HIS A O 1 ATOM 8402 C CB . HIS A 1 1022 ? 61.477 36.771 -6.371 1.00 18.72 ? 1022 HIS A CB 1 ATOM 8403 C CG . HIS A 1 1022 ? 62.883 36.888 -6.855 1.00 23.90 ? 1022 HIS A CG 1 ATOM 8404 N ND1 . HIS A 1 1022 ? 63.759 35.824 -6.850 1.00 29.10 ? 1022 HIS A ND1 1 ATOM 8405 C CD2 . HIS A 1 1022 ? 63.572 37.943 -7.352 1.00 25.81 ? 1022 HIS A CD2 1 ATOM 8406 C CE1 . HIS A 1 1022 ? 64.926 36.216 -7.335 1.00 29.13 ? 1022 HIS A CE1 1 ATOM 8407 N NE2 . HIS A 1 1022 ? 64.841 37.499 -7.641 1.00 29.27 ? 1022 HIS A NE2 1 ATOM 8408 N N . LEU A 1 1023 ? 60.749 38.076 -9.546 1.00 17.34 ? 1023 LEU A N 1 ATOM 8409 C CA . LEU A 1 1023 ? 60.460 37.844 -10.953 1.00 18.32 ? 1023 LEU A CA 1 ATOM 8410 C C . LEU A 1 1023 ? 61.617 37.252 -11.762 1.00 19.16 ? 1023 LEU A C 1 ATOM 8411 O O . LEU A 1 1023 ? 62.731 37.789 -11.770 1.00 18.85 ? 1023 LEU A O 1 ATOM 8412 C CB . LEU A 1 1023 ? 59.956 39.135 -11.598 1.00 17.85 ? 1023 LEU A CB 1 ATOM 8413 C CG . LEU A 1 1023 ? 58.548 39.488 -11.100 1.00 18.01 ? 1023 LEU A CG 1 ATOM 8414 C CD1 . LEU A 1 1023 ? 58.275 40.949 -11.295 1.00 21.64 ? 1023 LEU A CD1 1 ATOM 8415 C CD2 . LEU A 1 1023 ? 57.497 38.659 -11.823 1.00 21.55 ? 1023 LEU A CD2 1 ATOM 8416 N N . ASP A 1 1024 ? 61.324 36.159 -12.459 1.00 20.96 ? 1024 ASP A N 1 ATOM 8417 C CA . ASP A 1 1024 ? 62.327 35.465 -13.263 1.00 22.72 ? 1024 ASP A CA 1 ATOM 8418 C C . ASP A 1 1024 ? 62.949 36.371 -14.308 1.00 22.45 ? 1024 ASP A C 1 ATOM 8419 O O . ASP A 1 1024 ? 62.240 37.110 -15.015 1.00 23.01 ? 1024 ASP A O 1 ATOM 8420 C CB . ASP A 1 1024 ? 61.701 34.255 -13.947 1.00 23.80 ? 1024 ASP A CB 1 ATOM 8421 C CG . ASP A 1 1024 ? 61.232 33.202 -12.954 1.00 27.76 ? 1024 ASP A CG 1 ATOM 8422 O OD1 . ASP A 1 1024 ? 61.672 33.261 -11.775 1.00 32.71 ? 1024 ASP A OD1 1 ATOM 8423 O OD2 . ASP A 1 1024 ? 60.427 32.283 -13.265 1.00 33.51 ? 1024 ASP A OD2 1 ATOM 8424 N N . GLY A 1 1025 ? 64.276 36.331 -14.378 1.00 22.23 ? 1025 GLY A N 1 ATOM 8425 C CA . GLY A 1 1025 ? 65.025 37.072 -15.377 1.00 22.15 ? 1025 GLY A CA 1 ATOM 8426 C C . GLY A 1 1025 ? 64.927 38.569 -15.212 1.00 21.86 ? 1025 GLY A C 1 ATOM 8427 O O . GLY A 1 1025 ? 65.305 39.322 -16.106 1.00 22.45 ? 1025 GLY A O 1 ATOM 8428 N N . MET A 1 1026 ? 64.452 38.994 -14.039 1.00 20.74 ? 1026 MET A N 1 ATOM 8429 C CA . MET A 1 1026 ? 64.312 40.414 -13.704 1.00 21.60 ? 1026 MET A CA 1 ATOM 8430 C C . MET A 1 1026 ? 63.390 41.117 -14.684 1.00 20.04 ? 1026 MET A C 1 ATOM 8431 O O . MET A 1 1026 ? 63.568 42.318 -14.938 1.00 19.97 ? 1026 MET A O 1 ATOM 8432 C CB . MET A 1 1026 ? 65.670 41.121 -13.644 1.00 21.28 ? 1026 MET A CB 1 ATOM 8433 C CG . MET A 1 1026 ? 66.610 40.460 -12.657 1.00 23.00 ? 1026 MET A CG 1 ATOM 8434 S SD . MET A 1 1026 ? 68.245 41.181 -12.656 1.00 26.56 ? 1026 MET A SD 1 ATOM 8435 C CE . MET A 1 1026 ? 68.845 40.754 -14.342 1.00 29.17 ? 1026 MET A CE 1 ATOM 8436 N N . VAL A 1 1027 ? 62.418 40.379 -15.221 1.00 18.98 ? 1027 VAL A N 1 ATOM 8437 C CA . VAL A 1 1027 ? 61.454 40.927 -16.179 1.00 19.07 ? 1027 VAL A CA 1 ATOM 8438 C C . VAL A 1 1027 ? 60.093 41.124 -15.527 1.00 18.90 ? 1027 VAL A C 1 ATOM 8439 O O . VAL A 1 1027 ? 59.516 40.190 -14.952 1.00 18.20 ? 1027 VAL A O 1 ATOM 8440 C CB . VAL A 1 1027 ? 61.295 40.050 -17.455 1.00 18.72 ? 1027 VAL A CB 1 ATOM 8441 C CG1 . VAL A 1 1027 ? 60.110 40.536 -18.311 1.00 20.05 ? 1027 VAL A CG1 1 ATOM 8442 C CG2 . VAL A 1 1027 ? 62.587 40.033 -18.286 1.00 19.82 ? 1027 VAL A CG2 1 ATOM 8443 N N . ALA A 1 1028 ? 59.574 42.347 -15.641 1.00 17.97 ? 1028 ALA A N 1 ATOM 8444 C CA . ALA A 1 1028 ? 58.239 42.680 -15.131 1.00 18.29 ? 1028 ALA A CA 1 ATOM 8445 C C . ALA A 1 1028 ? 57.232 42.495 -16.241 1.00 18.25 ? 1028 ALA A C 1 ATOM 8446 O O . ALA A 1 1028 ? 57.224 43.278 -17.189 1.00 18.62 ? 1028 ALA A O 1 ATOM 8447 C CB . ALA A 1 1028 ? 58.194 44.113 -14.652 1.00 18.14 ? 1028 ALA A CB 1 ATOM 8448 N N . PRO A 1 1029 ? 56.350 41.514 -16.106 1.00 18.01 ? 1029 PRO A N 1 ATOM 8449 C CA . PRO A 1 1029 ? 55.331 41.241 -17.128 1.00 18.65 ? 1029 PRO A CA 1 ATOM 8450 C C . PRO A 1 1029 ? 54.345 42.401 -17.238 1.00 18.81 ? 1029 PRO A C 1 ATOM 8451 O O . PRO A 1 1029 ? 54.151 43.125 -16.272 1.00 20.00 ? 1029 PRO A O 1 ATOM 8452 C CB . PRO A 1 1029 ? 54.592 40.015 -16.582 1.00 18.57 ? 1029 PRO A CB 1 ATOM 8453 C CG . PRO A 1 1029 ? 55.437 39.487 -15.451 1.00 19.58 ? 1029 PRO A CG 1 ATOM 8454 C CD . PRO A 1 1029 ? 56.223 40.641 -14.925 1.00 17.96 ? 1029 PRO A CD 1 ATOM 8455 N N . GLU A 1 1030 ? 53.778 42.603 -18.411 1.00 18.37 ? 1030 GLU A N 1 ATOM 8456 C CA . GLU A 1 1030 ? 52.678 43.548 -18.544 1.00 19.57 ? 1030 GLU A CA 1 ATOM 8457 C C . GLU A 1 1030 ? 51.419 42.963 -17.897 1.00 19.62 ? 1030 GLU A C 1 ATOM 8458 O O . GLU A 1 1030 ? 51.301 41.731 -17.673 1.00 21.02 ? 1030 GLU A O 1 ATOM 8459 C CB . GLU A 1 1030 ? 52.422 43.853 -20.016 1.00 19.94 ? 1030 GLU A CB 1 ATOM 8460 C CG . GLU A 1 1030 ? 53.558 44.612 -20.698 1.00 19.98 ? 1030 GLU A CG 1 ATOM 8461 C CD . GLU A 1 1030 ? 53.263 44.919 -22.153 1.00 20.67 ? 1030 GLU A CD 1 ATOM 8462 O OE1 . GLU A 1 1030 ? 52.289 44.335 -22.703 1.00 23.20 ? 1030 GLU A OE1 1 ATOM 8463 O OE2 . GLU A 1 1030 ? 54.012 45.749 -22.748 1.00 18.30 ? 1030 GLU A OE2 1 ATOM 8464 N N . VAL A 1 1031 ? 50.487 43.852 -17.583 1.00 17.57 ? 1031 VAL A N 1 ATOM 8465 C CA . VAL A 1 1031 ? 49.280 43.495 -16.859 1.00 15.87 ? 1031 VAL A CA 1 ATOM 8466 C C . VAL A 1 1031 ? 48.118 43.251 -17.824 1.00 14.96 ? 1031 VAL A C 1 ATOM 8467 O O . VAL A 1 1031 ? 48.167 43.676 -18.983 1.00 15.42 ? 1031 VAL A O 1 ATOM 8468 C CB . VAL A 1 1031 ? 48.931 44.572 -15.799 1.00 16.22 ? 1031 VAL A CB 1 ATOM 8469 C CG1 . VAL A 1 1031 ? 50.066 44.673 -14.786 1.00 17.55 ? 1031 VAL A CG1 1 ATOM 8470 C CG2 . VAL A 1 1031 ? 48.638 45.934 -16.417 1.00 16.44 ? 1031 VAL A CG2 1 ATOM 8471 N N . CYS A 1 1032 ? 47.085 42.559 -17.356 1.00 13.70 ? 1032 CYS A N 1 ATOM 8472 C CA . CYS A 1 1032 ? 45.866 42.299 -18.125 1.00 13.83 ? 1032 CYS A CA 1 ATOM 8473 C C . CYS A 1 1032 ? 44.941 43.514 -18.198 1.00 11.32 ? 1032 CYS A C 1 ATOM 8474 O O . CYS A 1 1032 ? 45.063 44.417 -17.376 1.00 9.99 ? 1032 CYS A O 1 ATOM 8475 C CB . CYS A 1 1032 ? 45.092 41.195 -17.434 1.00 14.24 ? 1032 CYS A CB 1 ATOM 8476 S SG . CYS A 1 1032 ? 45.936 39.618 -17.660 1.00 22.69 ? 1032 CYS A SG 1 ATOM 8477 N N . PRO A 1 1033 ? 44.000 43.552 -19.146 1.00 10.41 ? 1033 PRO A N 1 ATOM 8478 C CA . PRO A 1 1033 ? 43.013 44.639 -19.176 1.00 10.07 ? 1033 PRO A CA 1 ATOM 8479 C C . PRO A 1 1033 ? 42.294 44.768 -17.845 1.00 8.40 ? 1033 PRO A C 1 ATOM 8480 O O . PRO A 1 1033 ? 41.837 43.782 -17.264 1.00 8.90 ? 1033 PRO A O 1 ATOM 8481 C CB . PRO A 1 1033 ? 42.028 44.191 -20.263 1.00 9.53 ? 1033 PRO A CB 1 ATOM 8482 C CG . PRO A 1 1033 ? 42.877 43.336 -21.166 1.00 11.91 ? 1033 PRO A CG 1 ATOM 8483 C CD . PRO A 1 1033 ? 43.802 42.589 -20.262 1.00 11.75 ? 1033 PRO A CD 1 ATOM 8484 N N . MET A 1 1034 ? 42.203 46.017 -17.402 1.00 8.01 ? 1034 MET A N 1 ATOM 8485 C CA . MET A 1 1034 ? 41.571 46.432 -16.161 1.00 9.29 ? 1034 MET A CA 1 ATOM 8486 C C . MET A 1 1034 ? 42.373 46.064 -14.931 1.00 9.92 ? 1034 MET A C 1 ATOM 8487 O O . MET A 1 1034 ? 41.911 46.298 -13.811 1.00 13.17 ? 1034 MET A O 1 ATOM 8488 C CB . MET A 1 1034 ? 40.100 46.010 -16.022 1.00 8.66 ? 1034 MET A CB 1 ATOM 8489 C CG . MET A 1 1034 ? 39.220 46.529 -17.150 1.00 11.30 ? 1034 MET A CG 1 ATOM 8490 S SD . MET A 1 1034 ? 39.276 48.299 -17.359 1.00 11.93 ? 1034 MET A SD 1 ATOM 8491 C CE . MET A 1 1034 ? 38.445 48.916 -15.832 1.00 12.70 ? 1034 MET A CE 1 ATOM 8492 N N . GLU A 1 1035 ? 43.593 45.596 -15.116 1.00 9.04 ? 1035 GLU A N 1 ATOM 8493 C CA . GLU A 1 1035 ? 44.418 45.302 -13.963 1.00 10.33 ? 1035 GLU A CA 1 ATOM 8494 C C . GLU A 1 1035 ? 45.468 46.376 -13.731 1.00 8.77 ? 1035 GLU A C 1 ATOM 8495 O O . GLU A 1 1035 ? 45.829 47.126 -14.637 1.00 7.91 ? 1035 GLU A O 1 ATOM 8496 C CB . GLU A 1 1035 ? 45.042 43.915 -14.098 1.00 13.04 ? 1035 GLU A CB 1 ATOM 8497 C CG . GLU A 1 1035 ? 43.993 42.774 -14.045 1.00 18.19 ? 1035 GLU A CG 1 ATOM 8498 C CD . GLU A 1 1035 ? 43.268 42.590 -12.697 1.00 27.68 ? 1035 GLU A CD 1 ATOM 8499 O OE1 . GLU A 1 1035 ? 43.026 43.574 -11.954 1.00 29.62 ? 1035 GLU A OE1 1 ATOM 8500 O OE2 . GLU A 1 1035 ? 42.904 41.429 -12.377 1.00 31.66 ? 1035 GLU A OE2 1 ATOM 8501 N N . THR A 1 1036 ? 45.936 46.455 -12.489 1.00 7.41 ? 1036 THR A N 1 ATOM 8502 C CA . THR A 1 1036 ? 47.004 47.351 -12.089 1.00 8.86 ? 1036 THR A CA 1 ATOM 8503 C C . THR A 1 1036 ? 47.956 46.525 -11.261 1.00 8.72 ? 1036 THR A C 1 ATOM 8504 O O . THR A 1 1036 ? 47.519 45.723 -10.418 1.00 10.36 ? 1036 THR A O 1 ATOM 8505 C CB . THR A 1 1036 ? 46.410 48.450 -11.213 1.00 8.24 ? 1036 THR A CB 1 ATOM 8506 O OG1 . THR A 1 1036 ? 45.329 49.090 -11.900 1.00 8.81 ? 1036 THR A OG1 1 ATOM 8507 C CG2 . THR A 1 1036 ? 47.371 49.572 -10.899 1.00 9.66 ? 1036 THR A CG2 1 ATOM 8508 N N . ALA A 1 1037 ? 49.247 46.698 -11.512 1.00 8.24 ? 1037 ALA A N 1 ATOM 8509 C CA . ALA A 1 1037 ? 50.284 45.990 -10.782 1.00 8.38 ? 1037 ALA A CA 1 ATOM 8510 C C . ALA A 1 1037 ? 51.394 46.931 -10.441 1.00 8.11 ? 1037 ALA A C 1 ATOM 8511 O O . ALA A 1 1037 ? 51.548 47.952 -11.109 1.00 9.21 ? 1037 ALA A O 1 ATOM 8512 C CB . ALA A 1 1037 ? 50.816 44.869 -11.621 1.00 10.67 ? 1037 ALA A CB 1 ATOM 8513 N N . ALA A 1 1038 ? 52.155 46.595 -9.419 1.00 6.96 ? 1038 ALA A N 1 ATOM 8514 C CA . ALA A 1 1038 ? 53.304 47.383 -9.050 1.00 6.90 ? 1038 ALA A CA 1 ATOM 8515 C C . ALA A 1 1038 ? 54.546 46.519 -9.079 1.00 7.25 ? 1038 ALA A C 1 ATOM 8516 O O . ALA A 1 1038 ? 54.480 45.334 -8.714 1.00 7.68 ? 1038 ALA A O 1 ATOM 8517 C CB . ALA A 1 1038 ? 53.129 48.014 -7.684 1.00 6.70 ? 1038 ALA A CB 1 ATOM 8518 N N . TYR A 1 1039 ? 55.654 47.135 -9.481 1.00 7.45 ? 1039 TYR A N 1 ATOM 8519 C CA . TYR A 1 1039 ? 56.931 46.444 -9.561 1.00 7.69 ? 1039 TYR A CA 1 ATOM 8520 C C . TYR A 1 1039 ? 57.985 47.338 -8.972 1.00 9.58 ? 1039 TYR A C 1 ATOM 8521 O O . TYR A 1 1039 ? 57.875 48.561 -9.062 1.00 9.76 ? 1039 TYR A O 1 ATOM 8522 C CB . TYR A 1 1039 ? 57.285 46.158 -11.005 1.00 9.54 ? 1039 TYR A CB 1 ATOM 8523 C CG . TYR A 1 1039 ? 56.318 45.280 -11.702 1.00 8.70 ? 1039 TYR A CG 1 ATOM 8524 C CD1 . TYR A 1 1039 ? 56.310 43.911 -11.468 1.00 9.62 ? 1039 TYR A CD1 1 ATOM 8525 C CD2 . TYR A 1 1039 ? 55.397 45.807 -12.623 1.00 11.56 ? 1039 TYR A CD2 1 ATOM 8526 C CE1 . TYR A 1 1039 ? 55.403 43.077 -12.142 1.00 10.06 ? 1039 TYR A CE1 1 ATOM 8527 C CE2 . TYR A 1 1039 ? 54.512 44.987 -13.278 1.00 11.25 ? 1039 TYR A CE2 1 ATOM 8528 C CZ . TYR A 1 1039 ? 54.512 43.641 -13.029 1.00 12.63 ? 1039 TYR A CZ 1 ATOM 8529 O OH . TYR A 1 1039 ? 53.641 42.839 -13.720 1.00 15.36 ? 1039 TYR A OH 1 ATOM 8530 N N . VAL A 1 1040 ? 58.987 46.735 -8.331 1.00 9.37 ? 1040 VAL A N 1 ATOM 8531 C CA . VAL A 1 1040 ? 60.132 47.492 -7.854 1.00 9.40 ? 1040 VAL A CA 1 ATOM 8532 C C . VAL A 1 1040 ? 61.356 46.862 -8.455 1.00 10.61 ? 1040 VAL A C 1 ATOM 8533 O O . VAL A 1 1040 ? 61.537 45.638 -8.343 1.00 9.67 ? 1040 VAL A O 1 ATOM 8534 C CB . VAL A 1 1040 ? 60.223 47.475 -6.330 1.00 9.70 ? 1040 VAL A CB 1 ATOM 8535 C CG1 . VAL A 1 1040 ? 61.537 48.113 -5.845 1.00 9.65 ? 1040 VAL A CG1 1 ATOM 8536 C CG2 . VAL A 1 1040 ? 59.031 48.253 -5.756 1.00 10.05 ? 1040 VAL A CG2 1 ATOM 8537 N N . SER A 1 1041 ? 62.149 47.666 -9.150 1.00 9.59 ? 1041 SER A N 1 ATOM 8538 C CA . SER A 1 1041 ? 63.447 47.218 -9.632 1.00 9.95 ? 1041 SER A CA 1 ATOM 8539 C C . SER A 1 1041 ? 64.530 47.682 -8.673 1.00 9.72 ? 1041 SER A C 1 ATOM 8540 O O . SER A 1 1041 ? 64.469 48.790 -8.148 1.00 9.95 ? 1041 SER A O 1 ATOM 8541 C CB . SER A 1 1041 ? 63.696 47.714 -11.062 1.00 11.17 ? 1041 SER A CB 1 ATOM 8542 O OG . SER A 1 1041 ? 63.707 49.124 -11.104 1.00 11.91 ? 1041 SER A OG 1 ATOM 8543 N N . SER A 1 1042 ? 65.533 46.816 -8.433 1.00 10.25 ? 1042 SER A N 1 ATOM 8544 C CA . SER A 1 1042 ? 66.647 47.135 -7.545 1.00 11.60 ? 1042 SER A CA 1 ATOM 8545 C C . SER A 1 1042 ? 67.896 47.193 -8.430 1.00 11.96 ? 1042 SER A C 1 ATOM 8546 O O . SER A 1 1042 ? 68.047 46.365 -9.319 1.00 12.67 ? 1042 SER A O 1 ATOM 8547 C CB . SER A 1 1042 ? 66.836 46.048 -6.478 1.00 12.66 ? 1042 SER A CB 1 ATOM 8548 O OG . SER A 1 1042 ? 65.672 45.937 -5.691 1.00 13.62 ? 1042 SER A OG 1 ATOM 8549 N N . HIS A 1 1043 ? 68.776 48.137 -8.139 1.00 13.33 ? 1043 HIS A N 1 ATOM 8550 C CA . HIS A 1 1043 ? 69.900 48.437 -9.013 1.00 14.71 ? 1043 HIS A CA 1 ATOM 8551 C C . HIS A 1 1043 ? 71.127 48.595 -8.167 1.00 15.91 ? 1043 HIS A C 1 ATOM 8552 O O . HIS A 1 1043 ? 71.124 49.274 -7.177 1.00 15.27 ? 1043 HIS A O 1 ATOM 8553 C CB . HIS A 1 1043 ? 69.633 49.715 -9.827 1.00 14.77 ? 1043 HIS A CB 1 ATOM 8554 C CG . HIS A 1 1043 ? 68.357 49.662 -10.598 1.00 14.82 ? 1043 HIS A CG 1 ATOM 8555 N ND1 . HIS A 1 1043 ? 68.293 49.263 -11.909 1.00 13.76 ? 1043 HIS A ND1 1 ATOM 8556 C CD2 . HIS A 1 1043 ? 67.081 49.881 -10.208 1.00 14.26 ? 1043 HIS A CD2 1 ATOM 8557 C CE1 . HIS A 1 1043 ? 67.033 49.263 -12.306 1.00 14.90 ? 1043 HIS A CE1 1 ATOM 8558 N NE2 . HIS A 1 1043 ? 66.280 49.636 -11.286 1.00 12.65 ? 1043 HIS A NE2 1 ATOM 8559 N N . SER A 1 1044 ? 72.204 47.965 -8.595 1.00 19.52 ? 1044 SER A N 1 ATOM 8560 C CA . SER A 1 1044 ? 73.438 48.131 -7.866 1.00 22.44 ? 1044 SER A CA 1 ATOM 8561 C C . SER A 1 1044 ? 74.037 49.507 -8.189 1.00 23.25 ? 1044 SER A C 1 ATOM 8562 O O . SER A 1 1044 ? 74.187 49.842 -9.339 1.00 23.92 ? 1044 SER A O 1 ATOM 8563 C CB . SER A 1 1044 ? 74.403 46.992 -8.205 1.00 23.15 ? 1044 SER A CB 1 ATOM 8564 O OG . SER A 1 1044 ? 73.901 46.168 -9.252 1.00 27.23 ? 1044 SER A OG 1 ATOM 8565 N N . SER A 1 1045 ? 74.346 50.293 -7.157 1.00 24.56 ? 1045 SER A N 1 ATOM 8566 C CA . SER A 1 1045 ? 74.815 51.671 -7.333 1.00 25.53 ? 1045 SER A CA 1 ATOM 8567 C C . SER A 1 1045 ? 76.096 51.993 -6.571 1.00 26.68 ? 1045 SER A C 1 ATOM 8568 O O . SER A 1 1045 ? 76.763 52.965 -6.887 1.00 27.51 ? 1045 SER A O 1 ATOM 8569 C CB . SER A 1 1045 ? 73.734 52.694 -6.982 1.00 25.31 ? 1045 SER A CB 1 ATOM 8570 O OG . SER A 1 1045 ? 73.690 52.984 -5.609 1.00 24.89 ? 1045 SER A OG 1 HETATM 8571 C C1 . NAG B 2 . ? 58.100 44.816 12.795 1.00 26.58 ? 1046 NAG A C1 1 HETATM 8572 C C2 . NAG B 2 . ? 59.145 44.493 13.850 1.00 33.03 ? 1046 NAG A C2 1 HETATM 8573 C C3 . NAG B 2 . ? 59.694 43.099 13.692 1.00 38.25 ? 1046 NAG A C3 1 HETATM 8574 C C4 . NAG B 2 . ? 58.554 42.184 14.078 1.00 46.11 ? 1046 NAG A C4 1 HETATM 8575 C C5 . NAG B 2 . ? 57.288 42.623 13.337 1.00 44.63 ? 1046 NAG A C5 1 HETATM 8576 C C6 . NAG B 2 . ? 57.177 42.022 11.957 1.00 53.75 ? 1046 NAG A C6 1 HETATM 8577 C C7 . NAG B 2 . ? 60.530 46.054 14.987 1.00 49.69 ? 1046 NAG A C7 1 HETATM 8578 C C8 . NAG B 2 . ? 59.799 45.522 16.227 1.00 51.28 ? 1046 NAG A C8 1 HETATM 8579 N N2 . NAG B 2 . ? 60.192 45.479 13.859 1.00 42.52 ? 1046 NAG A N2 1 HETATM 8580 O O3 . NAG B 2 . ? 60.776 42.967 14.612 1.00 57.93 ? 1046 NAG A O3 1 HETATM 8581 O O4 . NAG B 2 . ? 58.861 40.807 13.802 1.00 56.49 ? 1046 NAG A O4 1 HETATM 8582 O O5 . NAG B 2 . ? 57.007 44.068 13.230 1.00 36.51 ? 1046 NAG A O5 1 HETATM 8583 O O6 . NAG B 2 . ? 55.816 42.100 11.546 1.00 71.81 ? 1046 NAG A O6 1 HETATM 8584 O O7 . NAG B 2 . ? 61.356 46.955 15.054 1.00 66.78 ? 1046 NAG A O7 1 HETATM 8585 ZN ZN . ZN C 3 . ? 34.643 63.904 7.901 1.00 8.23 ? 1047 ZN A ZN 1 HETATM 8586 C C1 . MPD D 4 . ? 16.699 62.412 10.235 1.00 20.36 ? 1048 MPD A C1 1 HETATM 8587 C C2 . MPD D 4 . ? 16.224 60.980 10.507 1.00 18.36 ? 1048 MPD A C2 1 HETATM 8588 O O2 . MPD D 4 . ? 14.815 60.941 10.164 1.00 17.35 ? 1048 MPD A O2 1 HETATM 8589 C CM . MPD D 4 . ? 16.892 59.994 9.562 1.00 18.53 ? 1048 MPD A CM 1 HETATM 8590 C C3 . MPD D 4 . ? 16.198 60.485 11.958 1.00 17.15 ? 1048 MPD A C3 1 HETATM 8591 C C4 . MPD D 4 . ? 17.191 60.752 13.111 1.00 22.95 ? 1048 MPD A C4 1 HETATM 8592 O O4 . MPD D 4 . ? 17.577 59.520 13.741 1.00 12.17 ? 1048 MPD A O4 1 HETATM 8593 C C5 . MPD D 4 . ? 18.366 61.704 12.922 1.00 20.68 ? 1048 MPD A C5 1 HETATM 8594 C C1 . MPD E 4 . ? 54.178 78.392 -12.278 1.00 38.09 ? 1049 MPD A C1 1 HETATM 8595 C C2 . MPD E 4 . ? 53.599 77.258 -11.437 1.00 38.24 ? 1049 MPD A C2 1 HETATM 8596 O O2 . MPD E 4 . ? 54.624 76.749 -10.540 1.00 37.14 ? 1049 MPD A O2 1 HETATM 8597 C CM . MPD E 4 . ? 52.451 77.796 -10.597 1.00 37.55 ? 1049 MPD A CM 1 HETATM 8598 C C3 . MPD E 4 . ? 53.123 76.077 -12.282 1.00 38.11 ? 1049 MPD A C3 1 HETATM 8599 C C4 . MPD E 4 . ? 52.306 76.482 -13.507 1.00 38.63 ? 1049 MPD A C4 1 HETATM 8600 O O4 . MPD E 4 . ? 53.139 76.424 -14.648 1.00 39.00 ? 1049 MPD A O4 1 HETATM 8601 C C5 . MPD E 4 . ? 51.092 75.576 -13.666 1.00 36.63 ? 1049 MPD A C5 1 HETATM 8602 C C1 . MPD F 4 . ? 25.672 84.923 5.260 1.00 35.21 ? 1050 MPD A C1 1 HETATM 8603 C C2 . MPD F 4 . ? 26.905 85.797 5.050 1.00 35.89 ? 1050 MPD A C2 1 HETATM 8604 O O2 . MPD F 4 . ? 27.881 85.404 6.057 1.00 36.31 ? 1050 MPD A O2 1 HETATM 8605 C CM . MPD F 4 . ? 27.489 85.550 3.658 1.00 35.81 ? 1050 MPD A CM 1 HETATM 8606 C C3 . MPD F 4 . ? 26.600 87.276 5.288 1.00 33.88 ? 1050 MPD A C3 1 HETATM 8607 C C4 . MPD F 4 . ? 25.909 87.986 4.129 1.00 32.10 ? 1050 MPD A C4 1 HETATM 8608 O O4 . MPD F 4 . ? 24.576 87.523 4.015 1.00 31.96 ? 1050 MPD A O4 1 HETATM 8609 C C5 . MPD F 4 . ? 25.907 89.483 4.394 1.00 30.26 ? 1050 MPD A C5 1 HETATM 8610 O O . HOH G 5 . ? 33.764 65.900 7.339 1.00 19.92 ? 1051 HOH A O 1 HETATM 8611 O O . HOH G 5 . ? 31.623 67.415 5.939 1.00 12.26 ? 1052 HOH A O 1 HETATM 8612 O O . HOH G 5 . ? 32.548 65.310 10.068 1.00 22.84 ? 1053 HOH A O 1 HETATM 8613 O O . HOH G 5 . ? 30.826 64.038 9.113 1.00 16.88 ? 1054 HOH A O 1 HETATM 8614 O O . HOH G 5 . ? 30.186 65.263 6.877 1.00 24.53 ? 1055 HOH A O 1 HETATM 8615 O O . HOH G 5 . ? 27.849 66.551 7.751 1.00 23.83 ? 1056 HOH A O 1 HETATM 8616 O O . HOH G 5 . ? 26.072 64.790 8.296 1.00 25.17 ? 1057 HOH A O 1 HETATM 8617 O O . HOH G 5 . ? 24.180 63.306 7.340 1.00 10.67 ? 1058 HOH A O 1 HETATM 8618 O O . HOH G 5 . ? 24.643 61.249 9.016 1.00 13.12 ? 1059 HOH A O 1 HETATM 8619 O O . HOH G 5 . ? 27.154 61.045 10.126 1.00 26.84 ? 1060 HOH A O 1 HETATM 8620 O O . HOH G 5 . ? 27.259 59.262 8.321 1.00 26.54 ? 1061 HOH A O 1 HETATM 8621 O O . HOH G 5 . ? 23.810 57.978 6.231 1.00 10.98 ? 1062 HOH A O 1 HETATM 8622 O O . HOH G 5 . ? 21.684 56.994 4.986 1.00 11.53 ? 1063 HOH A O 1 HETATM 8623 O O . HOH G 5 . ? 20.085 55.876 7.086 1.00 9.85 ? 1064 HOH A O 1 HETATM 8624 O O . HOH G 5 . ? 17.575 52.638 6.257 1.00 8.21 ? 1065 HOH A O 1 HETATM 8625 O O . HOH G 5 . ? 19.321 53.421 8.123 1.00 8.26 ? 1066 HOH A O 1 HETATM 8626 O O . HOH G 5 . ? 20.088 54.636 16.059 1.00 9.32 ? 1067 HOH A O 1 HETATM 8627 O O . HOH G 5 . ? 18.295 54.765 14.060 1.00 9.28 ? 1068 HOH A O 1 HETATM 8628 O O . HOH G 5 . ? 19.308 55.095 11.466 1.00 11.40 ? 1069 HOH A O 1 HETATM 8629 O O . HOH G 5 . ? 17.019 56.134 10.187 1.00 9.49 ? 1070 HOH A O 1 HETATM 8630 O O . HOH G 5 . ? 16.666 56.920 12.917 1.00 10.61 ? 1071 HOH A O 1 HETATM 8631 O O . HOH G 5 . ? 15.438 60.222 15.376 1.00 11.99 ? 1072 HOH A O 1 HETATM 8632 O O . HOH G 5 . ? 13.768 62.231 14.566 1.00 21.77 ? 1073 HOH A O 1 HETATM 8633 O O . HOH G 5 . ? 11.468 61.651 15.966 1.00 32.22 ? 1074 HOH A O 1 HETATM 8634 O O . HOH G 5 . ? 8.627 61.369 18.922 1.00 42.55 ? 1075 HOH A O 1 HETATM 8635 O O . HOH G 5 . ? 11.864 62.193 23.250 1.00 36.42 ? 1076 HOH A O 1 HETATM 8636 O O . HOH G 5 . ? 12.117 60.745 20.293 1.00 34.97 ? 1077 HOH A O 1 HETATM 8637 O O . HOH G 5 . ? 11.489 58.223 19.966 1.00 28.40 ? 1078 HOH A O 1 HETATM 8638 O O . HOH G 5 . ? 13.884 57.501 18.923 1.00 16.90 ? 1079 HOH A O 1 HETATM 8639 O O . HOH G 5 . ? 13.931 58.076 16.244 1.00 12.33 ? 1080 HOH A O 1 HETATM 8640 O O . HOH G 5 . ? 11.338 58.536 16.070 1.00 27.80 ? 1081 HOH A O 1 HETATM 8641 O O . HOH G 5 . ? 28.524 63.593 10.292 1.00 36.50 ? 1082 HOH A O 1 HETATM 8642 O O . HOH G 5 . ? 29.414 65.323 12.214 1.00 35.04 ? 1083 HOH A O 1 HETATM 8643 O O . HOH G 5 . ? 28.542 68.900 12.338 1.00 32.97 ? 1084 HOH A O 1 HETATM 8644 O O . HOH G 5 . ? 29.705 71.831 12.140 1.00 19.43 ? 1085 HOH A O 1 HETATM 8645 O O . HOH G 5 . ? 31.858 70.725 13.371 1.00 24.51 ? 1086 HOH A O 1 HETATM 8646 O O . HOH G 5 . ? 31.006 68.068 13.940 1.00 24.04 ? 1087 HOH A O 1 HETATM 8647 O O . HOH G 5 . ? 29.228 66.851 15.492 1.00 35.82 ? 1088 HOH A O 1 HETATM 8648 O O . HOH G 5 . ? 29.848 66.824 18.016 1.00 27.14 ? 1089 HOH A O 1 HETATM 8649 O O . HOH G 5 . ? 31.873 65.473 18.949 1.00 14.67 ? 1090 HOH A O 1 HETATM 8650 O O . HOH G 5 . ? 33.413 68.466 17.000 1.00 34.81 ? 1091 HOH A O 1 HETATM 8651 O O . HOH G 5 . ? 35.269 70.784 16.013 1.00 43.53 ? 1092 HOH A O 1 HETATM 8652 O O . HOH G 5 . ? 35.371 73.366 15.209 1.00 37.07 ? 1093 HOH A O 1 HETATM 8653 O O . HOH G 5 . ? 34.962 76.217 14.933 1.00 34.72 ? 1094 HOH A O 1 HETATM 8654 O O . HOH G 5 . ? 22.844 48.903 -36.303 1.00 30.85 ? 1095 HOH A O 1 HETATM 8655 O O . HOH G 5 . ? 21.798 47.156 -34.727 1.00 30.45 ? 1096 HOH A O 1 HETATM 8656 O O . HOH G 5 . ? 20.534 50.966 -37.948 1.00 28.54 ? 1097 HOH A O 1 HETATM 8657 O O . HOH G 5 . ? 20.985 55.167 -35.936 1.00 30.44 ? 1098 HOH A O 1 HETATM 8658 O O . HOH G 5 . ? 19.662 54.929 -33.540 1.00 33.64 ? 1099 HOH A O 1 HETATM 8659 O O . HOH G 5 . ? 19.168 57.708 -32.905 1.00 32.50 ? 1100 HOH A O 1 HETATM 8660 O O . HOH G 5 . ? 20.843 58.999 -34.512 1.00 16.11 ? 1101 HOH A O 1 HETATM 8661 O O . HOH G 5 . ? 22.222 61.302 -35.034 1.00 28.38 ? 1102 HOH A O 1 HETATM 8662 O O . HOH G 5 . ? 22.724 63.196 -33.139 1.00 15.38 ? 1103 HOH A O 1 HETATM 8663 O O . HOH G 5 . ? 24.917 59.271 -36.270 1.00 34.85 ? 1104 HOH A O 1 HETATM 8664 O O . HOH G 5 . ? 26.224 58.936 -38.974 1.00 41.29 ? 1105 HOH A O 1 HETATM 8665 O O . HOH G 5 . ? 28.609 59.791 -39.157 1.00 29.98 ? 1106 HOH A O 1 HETATM 8666 O O . HOH G 5 . ? 29.142 62.140 -39.763 1.00 19.95 ? 1107 HOH A O 1 HETATM 8667 O O . HOH G 5 . ? 31.336 58.325 -40.234 1.00 31.33 ? 1108 HOH A O 1 HETATM 8668 O O . HOH G 5 . ? 33.717 57.604 -38.999 1.00 34.35 ? 1109 HOH A O 1 HETATM 8669 O O . HOH G 5 . ? 33.691 56.993 -35.900 1.00 16.63 ? 1110 HOH A O 1 HETATM 8670 O O . HOH G 5 . ? 34.857 59.338 -34.869 1.00 17.61 ? 1111 HOH A O 1 HETATM 8671 O O . HOH G 5 . ? 37.035 58.775 -33.259 1.00 23.95 ? 1112 HOH A O 1 HETATM 8672 O O . HOH G 5 . ? 39.354 58.367 -34.535 1.00 34.80 ? 1113 HOH A O 1 HETATM 8673 O O . HOH G 5 . ? 40.835 56.010 -33.248 1.00 25.27 ? 1114 HOH A O 1 HETATM 8674 O O . HOH G 5 . ? 38.778 55.135 -31.676 1.00 17.67 ? 1115 HOH A O 1 HETATM 8675 O O . HOH G 5 . ? 36.987 52.616 -32.177 1.00 38.30 ? 1116 HOH A O 1 HETATM 8676 O O . HOH G 5 . ? 34.650 53.760 -33.014 1.00 34.99 ? 1117 HOH A O 1 HETATM 8677 O O . HOH G 5 . ? 35.665 55.270 -34.712 1.00 34.49 ? 1118 HOH A O 1 HETATM 8678 O O . HOH G 5 . ? 35.747 59.724 -37.726 1.00 34.95 ? 1119 HOH A O 1 HETATM 8679 O O . HOH G 5 . ? 36.551 62.584 -38.276 1.00 29.60 ? 1120 HOH A O 1 HETATM 8680 O O A HOH G 5 . ? 36.269 63.455 -33.909 0.50 24.28 ? 1121 HOH A O 1 HETATM 8681 O O B HOH G 5 . ? 35.253 62.385 -33.129 0.50 19.99 ? 1121 HOH A O 1 HETATM 8682 O O . HOH G 5 . ? 34.056 64.340 -32.291 1.00 13.61 ? 1122 HOH A O 1 HETATM 8683 O O . HOH G 5 . ? 37.667 61.343 -32.432 1.00 22.78 ? 1123 HOH A O 1 HETATM 8684 O O . HOH G 5 . ? 40.351 62.381 -31.971 1.00 18.69 ? 1124 HOH A O 1 HETATM 8685 O O . HOH G 5 . ? 42.395 62.137 -34.028 1.00 40.08 ? 1125 HOH A O 1 HETATM 8686 O O . HOH G 5 . ? 42.967 64.098 -31.401 1.00 37.55 ? 1126 HOH A O 1 HETATM 8687 O O . HOH G 5 . ? 43.442 66.654 -31.958 1.00 26.03 ? 1127 HOH A O 1 HETATM 8688 O O . HOH G 5 . ? 41.219 68.251 -32.516 1.00 15.47 ? 1128 HOH A O 1 HETATM 8689 O O . HOH G 5 . ? 42.621 68.856 -29.850 1.00 34.23 ? 1129 HOH A O 1 HETATM 8690 O O . HOH G 5 . ? 45.777 68.002 -27.093 1.00 25.33 ? 1130 HOH A O 1 HETATM 8691 O O . HOH G 5 . ? 45.595 65.972 -28.561 1.00 33.26 ? 1131 HOH A O 1 HETATM 8692 O O . HOH G 5 . ? 48.147 64.344 -28.488 1.00 23.53 ? 1132 HOH A O 1 HETATM 8693 O O . HOH G 5 . ? 46.192 62.706 -28.223 1.00 26.10 ? 1133 HOH A O 1 HETATM 8694 O O . HOH G 5 . ? 43.582 63.008 -28.606 1.00 22.29 ? 1134 HOH A O 1 HETATM 8695 O O . HOH G 5 . ? 41.732 61.184 -29.698 1.00 16.67 ? 1135 HOH A O 1 HETATM 8696 O O . HOH G 5 . ? 42.998 59.466 -31.459 1.00 23.25 ? 1136 HOH A O 1 HETATM 8697 O O . HOH G 5 . ? 42.945 56.662 -31.441 1.00 22.11 ? 1137 HOH A O 1 HETATM 8698 O O . HOH G 5 . ? 45.568 56.317 -32.516 1.00 43.02 ? 1138 HOH A O 1 HETATM 8699 O O . HOH G 5 . ? 47.638 57.898 -32.278 1.00 39.38 ? 1139 HOH A O 1 HETATM 8700 O O . HOH G 5 . ? 49.041 59.362 -28.456 1.00 35.47 ? 1140 HOH A O 1 HETATM 8701 O O . HOH G 5 . ? 47.906 59.248 -25.572 1.00 14.22 ? 1141 HOH A O 1 HETATM 8702 O O . HOH G 5 . ? 46.815 61.811 -25.677 1.00 20.06 ? 1142 HOH A O 1 HETATM 8703 O O . HOH G 5 . ? 48.265 64.996 -25.575 1.00 33.44 ? 1143 HOH A O 1 HETATM 8704 O O . HOH G 5 . ? 47.040 68.125 -24.432 1.00 21.68 ? 1144 HOH A O 1 HETATM 8705 O O . HOH G 5 . ? 47.256 70.916 -24.390 1.00 31.46 ? 1145 HOH A O 1 HETATM 8706 O O . HOH G 5 . ? 48.393 72.366 -26.247 1.00 32.83 ? 1146 HOH A O 1 HETATM 8707 O O . HOH G 5 . ? 50.296 73.920 -25.388 1.00 24.06 ? 1147 HOH A O 1 HETATM 8708 O O . HOH G 5 . ? 47.120 74.870 -25.484 1.00 41.17 ? 1148 HOH A O 1 HETATM 8709 O O . HOH G 5 . ? 46.325 77.512 -26.086 1.00 32.99 ? 1149 HOH A O 1 HETATM 8710 O O . HOH G 5 . ? 46.699 80.421 -22.747 1.00 33.46 ? 1150 HOH A O 1 HETATM 8711 O O . HOH G 5 . ? 45.929 82.398 -26.096 1.00 42.15 ? 1151 HOH A O 1 HETATM 8712 O O . HOH G 5 . ? 44.349 83.668 -27.754 1.00 26.25 ? 1152 HOH A O 1 HETATM 8713 O O . HOH G 5 . ? 44.718 82.513 -30.786 1.00 25.62 ? 1153 HOH A O 1 HETATM 8714 O O . HOH G 5 . ? 42.464 79.691 -31.681 1.00 36.99 ? 1154 HOH A O 1 HETATM 8715 O O . HOH G 5 . ? 44.544 79.190 -33.349 1.00 24.71 ? 1155 HOH A O 1 HETATM 8716 O O . HOH G 5 . ? 42.779 79.844 -28.291 1.00 43.12 ? 1156 HOH A O 1 HETATM 8717 O O . HOH G 5 . ? 41.270 82.664 -28.960 1.00 35.54 ? 1157 HOH A O 1 HETATM 8718 O O . HOH G 5 . ? 40.547 82.903 -31.272 1.00 22.24 ? 1158 HOH A O 1 HETATM 8719 O O . HOH G 5 . ? 38.163 81.662 -31.391 1.00 11.69 ? 1159 HOH A O 1 HETATM 8720 O O . HOH G 5 . ? 39.068 83.209 -27.479 1.00 22.06 ? 1160 HOH A O 1 HETATM 8721 O O . HOH G 5 . ? 41.350 83.352 -26.411 1.00 26.83 ? 1161 HOH A O 1 HETATM 8722 O O . HOH G 5 . ? 40.384 85.790 -22.211 1.00 26.88 ? 1162 HOH A O 1 HETATM 8723 O O . HOH G 5 . ? 42.517 86.475 -20.964 1.00 34.71 ? 1163 HOH A O 1 HETATM 8724 O O . HOH G 5 . ? 47.164 84.376 -18.756 1.00 36.65 ? 1164 HOH A O 1 HETATM 8725 O O . HOH G 5 . ? 47.391 79.699 -18.197 1.00 19.57 ? 1165 HOH A O 1 HETATM 8726 O O . HOH G 5 . ? 50.484 79.081 -15.510 1.00 23.62 ? 1166 HOH A O 1 HETATM 8727 O O . HOH G 5 . ? 52.238 79.124 -17.603 1.00 22.38 ? 1167 HOH A O 1 HETATM 8728 O O . HOH G 5 . ? 54.061 80.501 -19.005 1.00 36.87 ? 1168 HOH A O 1 HETATM 8729 O O . HOH G 5 . ? 57.002 80.049 -18.168 1.00 29.65 ? 1169 HOH A O 1 HETATM 8730 O O . HOH G 5 . ? 56.169 78.815 -14.605 1.00 23.33 ? 1170 HOH A O 1 HETATM 8731 O O . HOH G 5 . ? 56.923 80.054 -11.185 1.00 29.91 ? 1171 HOH A O 1 HETATM 8732 O O . HOH G 5 . ? 60.648 80.088 -12.109 1.00 31.97 ? 1172 HOH A O 1 HETATM 8733 O O . HOH G 5 . ? 61.320 77.432 -12.780 1.00 18.41 ? 1173 HOH A O 1 HETATM 8734 O O . HOH G 5 . ? 61.709 76.374 -10.377 1.00 14.80 ? 1174 HOH A O 1 HETATM 8735 O O . HOH G 5 . ? 59.421 76.542 -8.859 1.00 12.03 ? 1175 HOH A O 1 HETATM 8736 O O . HOH G 5 . ? 65.226 79.792 -8.820 1.00 25.49 ? 1176 HOH A O 1 HETATM 8737 O O . HOH G 5 . ? 65.307 78.554 -5.657 1.00 28.08 ? 1177 HOH A O 1 HETATM 8738 O O . HOH G 5 . ? 65.101 76.742 -3.729 1.00 32.80 ? 1178 HOH A O 1 HETATM 8739 O O . HOH G 5 . ? 66.845 74.113 -4.310 1.00 24.12 ? 1179 HOH A O 1 HETATM 8740 O O . HOH G 5 . ? 69.147 73.864 -3.297 1.00 37.13 ? 1180 HOH A O 1 HETATM 8741 O O . HOH G 5 . ? 70.728 73.264 -1.727 1.00 34.41 ? 1181 HOH A O 1 HETATM 8742 O O . HOH G 5 . ? 73.701 73.986 -5.693 1.00 24.94 ? 1182 HOH A O 1 HETATM 8743 O O . HOH G 5 . ? 75.648 72.142 -5.864 1.00 37.83 ? 1183 HOH A O 1 HETATM 8744 O O . HOH G 5 . ? 75.415 76.120 -5.791 1.00 40.94 ? 1184 HOH A O 1 HETATM 8745 O O . HOH G 5 . ? 73.664 81.021 -3.977 1.00 27.75 ? 1185 HOH A O 1 HETATM 8746 O O . HOH G 5 . ? 71.476 80.506 -4.684 1.00 46.92 ? 1186 HOH A O 1 HETATM 8747 O O . HOH G 5 . ? 70.519 83.223 -10.079 1.00 37.67 ? 1187 HOH A O 1 HETATM 8748 O O . HOH G 5 . ? 67.988 82.777 -9.870 1.00 33.56 ? 1188 HOH A O 1 HETATM 8749 O O . HOH G 5 . ? 66.839 81.434 -11.336 1.00 30.93 ? 1189 HOH A O 1 HETATM 8750 O O . HOH G 5 . ? 66.266 81.756 -14.237 1.00 26.65 ? 1190 HOH A O 1 HETATM 8751 O O . HOH G 5 . ? 63.446 81.924 -14.373 1.00 38.11 ? 1191 HOH A O 1 HETATM 8752 O O . HOH G 5 . ? 62.544 82.612 -16.935 1.00 39.41 ? 1192 HOH A O 1 HETATM 8753 O O . HOH G 5 . ? 61.837 80.707 -18.781 1.00 21.53 ? 1193 HOH A O 1 HETATM 8754 O O . HOH G 5 . ? 62.684 82.884 -20.536 1.00 42.34 ? 1194 HOH A O 1 HETATM 8755 O O . HOH G 5 . ? 62.069 85.446 -22.864 1.00 25.57 ? 1195 HOH A O 1 HETATM 8756 O O . HOH G 5 . ? 62.387 87.267 -20.872 1.00 37.72 ? 1196 HOH A O 1 HETATM 8757 O O . HOH G 5 . ? 63.964 89.463 -22.207 1.00 23.68 ? 1197 HOH A O 1 HETATM 8758 O O . HOH G 5 . ? 65.057 87.949 -24.169 1.00 22.43 ? 1198 HOH A O 1 HETATM 8759 O O . HOH G 5 . ? 67.514 88.045 -23.430 1.00 24.77 ? 1199 HOH A O 1 HETATM 8760 O O . HOH G 5 . ? 66.409 89.147 -21.010 1.00 33.21 ? 1200 HOH A O 1 HETATM 8761 O O . HOH G 5 . ? 66.598 84.558 -22.179 1.00 26.79 ? 1201 HOH A O 1 HETATM 8762 O O . HOH G 5 . ? 67.649 81.700 -25.592 1.00 12.33 ? 1202 HOH A O 1 HETATM 8763 O O . HOH G 5 . ? 67.579 78.963 -25.258 1.00 12.63 ? 1203 HOH A O 1 HETATM 8764 O O . HOH G 5 . ? 70.255 78.046 -25.854 1.00 23.91 ? 1204 HOH A O 1 HETATM 8765 O O . HOH G 5 . ? 72.410 75.988 -27.070 1.00 39.54 ? 1205 HOH A O 1 HETATM 8766 O O . HOH G 5 . ? 71.494 73.905 -28.978 1.00 26.36 ? 1206 HOH A O 1 HETATM 8767 O O . HOH G 5 . ? 72.723 71.335 -29.677 1.00 41.13 ? 1207 HOH A O 1 HETATM 8768 O O . HOH G 5 . ? 71.707 69.237 -31.325 1.00 38.95 ? 1208 HOH A O 1 HETATM 8769 O O . HOH G 5 . ? 71.356 69.698 -35.077 1.00 34.60 ? 1209 HOH A O 1 HETATM 8770 O O . HOH G 5 . ? 70.925 72.150 -34.298 1.00 41.12 ? 1210 HOH A O 1 HETATM 8771 O O . HOH G 5 . ? 68.322 72.842 -33.747 1.00 34.14 ? 1211 HOH A O 1 HETATM 8772 O O . HOH G 5 . ? 67.853 75.105 -35.064 1.00 24.32 ? 1212 HOH A O 1 HETATM 8773 O O . HOH G 5 . ? 68.965 77.024 -34.246 1.00 27.71 ? 1213 HOH A O 1 HETATM 8774 O O . HOH G 5 . ? 68.245 79.503 -34.665 1.00 26.67 ? 1214 HOH A O 1 HETATM 8775 O O . HOH G 5 . ? 68.445 79.574 -37.403 1.00 34.36 ? 1215 HOH A O 1 HETATM 8776 O O . HOH G 5 . ? 67.715 77.290 -38.680 1.00 32.44 ? 1216 HOH A O 1 HETATM 8777 O O . HOH G 5 . ? 64.079 78.559 -37.720 1.00 28.68 ? 1217 HOH A O 1 HETATM 8778 O O . HOH G 5 . ? 64.246 77.879 -35.226 1.00 11.87 ? 1218 HOH A O 1 HETATM 8779 O O . HOH G 5 . ? 63.870 76.939 -40.275 1.00 33.97 ? 1219 HOH A O 1 HETATM 8780 O O . HOH G 5 . ? 61.171 76.592 -39.760 1.00 19.74 ? 1220 HOH A O 1 HETATM 8781 O O . HOH G 5 . ? 60.606 78.679 -41.435 1.00 31.66 ? 1221 HOH A O 1 HETATM 8782 O O . HOH G 5 . ? 62.833 80.576 -42.288 1.00 37.10 ? 1222 HOH A O 1 HETATM 8783 O O . HOH G 5 . ? 61.934 81.430 -44.441 1.00 36.42 ? 1223 HOH A O 1 HETATM 8784 O O . HOH G 5 . ? 61.818 83.173 -38.232 1.00 25.61 ? 1224 HOH A O 1 HETATM 8785 O O . HOH G 5 . ? 66.217 84.141 -38.691 1.00 39.03 ? 1225 HOH A O 1 HETATM 8786 O O . HOH G 5 . ? 68.283 82.256 -38.249 1.00 38.16 ? 1226 HOH A O 1 HETATM 8787 O O . HOH G 5 . ? 69.156 83.711 -35.936 1.00 23.90 ? 1227 HOH A O 1 HETATM 8788 O O . HOH G 5 . ? 69.562 81.916 -33.962 1.00 34.54 ? 1228 HOH A O 1 HETATM 8789 O O . HOH G 5 . ? 71.614 82.363 -31.937 1.00 40.17 ? 1229 HOH A O 1 HETATM 8790 O O . HOH G 5 . ? 69.838 83.079 -29.471 1.00 23.87 ? 1230 HOH A O 1 HETATM 8791 O O . HOH G 5 . ? 71.155 82.248 -27.563 1.00 40.89 ? 1231 HOH A O 1 HETATM 8792 O O . HOH G 5 . ? 68.261 79.285 -28.566 1.00 24.03 ? 1232 HOH A O 1 HETATM 8793 O O . HOH G 5 . ? 71.206 76.541 -35.784 1.00 34.94 ? 1233 HOH A O 1 HETATM 8794 O O . HOH G 5 . ? 65.870 74.627 -41.237 1.00 37.36 ? 1234 HOH A O 1 HETATM 8795 O O . HOH G 5 . ? 64.406 72.595 -45.486 1.00 42.22 ? 1235 HOH A O 1 HETATM 8796 O O . HOH G 5 . ? 63.032 74.683 -45.932 1.00 33.04 ? 1236 HOH A O 1 HETATM 8797 O O . HOH G 5 . ? 55.367 73.157 -43.467 1.00 52.39 ? 1237 HOH A O 1 HETATM 8798 O O . HOH G 5 . ? 53.271 76.694 -43.922 1.00 34.56 ? 1238 HOH A O 1 HETATM 8799 O O . HOH G 5 . ? 53.004 79.033 -44.921 1.00 47.14 ? 1239 HOH A O 1 HETATM 8800 O O . HOH G 5 . ? 50.592 80.062 -45.523 1.00 39.12 ? 1240 HOH A O 1 HETATM 8801 O O . HOH G 5 . ? 49.709 82.184 -43.880 1.00 17.25 ? 1241 HOH A O 1 HETATM 8802 O O . HOH G 5 . ? 47.263 83.936 -43.985 1.00 40.04 ? 1242 HOH A O 1 HETATM 8803 O O . HOH G 5 . ? 44.991 83.215 -43.215 1.00 40.58 ? 1243 HOH A O 1 HETATM 8804 O O . HOH G 5 . ? 46.481 80.126 -42.521 1.00 23.69 ? 1244 HOH A O 1 HETATM 8805 O O . HOH G 5 . ? 47.440 78.850 -40.490 1.00 18.93 ? 1245 HOH A O 1 HETATM 8806 O O . HOH G 5 . ? 43.772 79.903 -42.557 1.00 27.19 ? 1246 HOH A O 1 HETATM 8807 O O . HOH G 5 . ? 43.504 77.262 -43.445 1.00 37.04 ? 1247 HOH A O 1 HETATM 8808 O O . HOH G 5 . ? 42.137 74.620 -41.426 1.00 21.50 ? 1248 HOH A O 1 HETATM 8809 O O . HOH G 5 . ? 43.756 72.427 -41.946 1.00 16.96 ? 1249 HOH A O 1 HETATM 8810 O O . HOH G 5 . ? 44.564 71.974 -44.364 1.00 29.42 ? 1250 HOH A O 1 HETATM 8811 O O . HOH G 5 . ? 46.154 70.172 -39.651 1.00 26.30 ? 1251 HOH A O 1 HETATM 8812 O O . HOH G 5 . ? 48.882 69.857 -40.553 1.00 35.38 ? 1252 HOH A O 1 HETATM 8813 O O . HOH G 5 . ? 51.544 69.989 -40.451 1.00 33.69 ? 1253 HOH A O 1 HETATM 8814 O O . HOH G 5 . ? 51.579 70.076 -37.946 1.00 22.10 ? 1254 HOH A O 1 HETATM 8815 O O . HOH G 5 . ? 53.871 71.175 -36.788 1.00 11.43 ? 1255 HOH A O 1 HETATM 8816 O O . HOH G 5 . ? 55.250 69.046 -37.710 1.00 23.93 ? 1256 HOH A O 1 HETATM 8817 O O . HOH G 5 . ? 56.783 69.959 -39.704 1.00 23.18 ? 1257 HOH A O 1 HETATM 8818 O O . HOH G 5 . ? 59.890 68.593 -38.918 1.00 28.82 ? 1258 HOH A O 1 HETATM 8819 O O . HOH G 5 . ? 60.981 67.529 -36.589 1.00 33.50 ? 1259 HOH A O 1 HETATM 8820 O O . HOH G 5 . ? 59.134 67.238 -34.679 1.00 27.92 ? 1260 HOH A O 1 HETATM 8821 O O . HOH G 5 . ? 56.605 67.637 -35.421 1.00 24.39 ? 1261 HOH A O 1 HETATM 8822 O O . HOH G 5 . ? 56.081 65.229 -36.058 1.00 25.95 ? 1262 HOH A O 1 HETATM 8823 O O . HOH G 5 . ? 58.585 64.625 -36.630 1.00 33.33 ? 1263 HOH A O 1 HETATM 8824 O O . HOH G 5 . ? 53.800 64.103 -38.205 1.00 31.82 ? 1264 HOH A O 1 HETATM 8825 O O . HOH G 5 . ? 49.918 61.669 -33.952 1.00 36.71 ? 1265 HOH A O 1 HETATM 8826 O O . HOH G 5 . ? 50.469 61.086 -30.979 1.00 24.31 ? 1266 HOH A O 1 HETATM 8827 O O . HOH G 5 . ? 53.673 59.685 -32.458 1.00 30.38 ? 1267 HOH A O 1 HETATM 8828 O O . HOH G 5 . ? 55.178 58.924 -34.146 1.00 33.90 ? 1268 HOH A O 1 HETATM 8829 O O . HOH G 5 . ? 53.090 57.499 -33.656 1.00 47.01 ? 1269 HOH A O 1 HETATM 8830 O O . HOH G 5 . ? 53.315 54.974 -31.961 1.00 36.92 ? 1270 HOH A O 1 HETATM 8831 O O . HOH G 5 . ? 52.092 56.315 -30.233 1.00 20.77 ? 1271 HOH A O 1 HETATM 8832 O O . HOH G 5 . ? 49.825 55.049 -29.083 1.00 15.42 ? 1272 HOH A O 1 HETATM 8833 O O . HOH G 5 . ? 51.215 52.729 -28.632 1.00 18.32 ? 1273 HOH A O 1 HETATM 8834 O O . HOH G 5 . ? 53.499 53.211 -30.003 1.00 25.90 ? 1274 HOH A O 1 HETATM 8835 O O . HOH G 5 . ? 56.576 53.890 -32.780 1.00 45.49 ? 1275 HOH A O 1 HETATM 8836 O O . HOH G 5 . ? 58.973 54.108 -33.272 1.00 32.45 ? 1276 HOH A O 1 HETATM 8837 O O . HOH G 5 . ? 58.210 52.308 -31.664 1.00 36.91 ? 1277 HOH A O 1 HETATM 8838 O O . HOH G 5 . ? 60.088 52.817 -30.332 1.00 32.13 ? 1278 HOH A O 1 HETATM 8839 O O . HOH G 5 . ? 61.355 54.425 -28.956 1.00 21.13 ? 1279 HOH A O 1 HETATM 8840 O O . HOH G 5 . ? 62.976 50.879 -29.195 1.00 38.73 ? 1280 HOH A O 1 HETATM 8841 O O . HOH G 5 . ? 62.167 51.947 -32.163 1.00 41.07 ? 1281 HOH A O 1 HETATM 8842 O O . HOH G 5 . ? 64.745 55.347 -31.302 1.00 35.43 ? 1282 HOH A O 1 HETATM 8843 O O . HOH G 5 . ? 66.918 59.974 -27.009 1.00 23.05 ? 1283 HOH A O 1 HETATM 8844 O O . HOH G 5 . ? 67.903 58.728 -23.976 1.00 17.30 ? 1284 HOH A O 1 HETATM 8845 O O . HOH G 5 . ? 68.175 56.973 -22.115 1.00 36.66 ? 1285 HOH A O 1 HETATM 8846 O O . HOH G 5 . ? 66.525 56.204 -20.135 1.00 17.13 ? 1286 HOH A O 1 HETATM 8847 O O . HOH G 5 . ? 67.638 54.701 -18.087 1.00 25.42 ? 1287 HOH A O 1 HETATM 8848 O O . HOH G 5 . ? 69.959 53.771 -19.506 1.00 40.21 ? 1288 HOH A O 1 HETATM 8849 O O . HOH G 5 . ? 66.053 53.368 -20.379 1.00 36.13 ? 1289 HOH A O 1 HETATM 8850 O O . HOH G 5 . ? 65.010 51.942 -22.374 1.00 42.30 ? 1290 HOH A O 1 HETATM 8851 O O . HOH G 5 . ? 64.507 49.417 -21.460 1.00 39.15 ? 1291 HOH A O 1 HETATM 8852 O O . HOH G 5 . ? 62.024 48.265 -20.867 1.00 34.25 ? 1292 HOH A O 1 HETATM 8853 O O . HOH G 5 . ? 60.931 46.775 -22.377 1.00 31.68 ? 1293 HOH A O 1 HETATM 8854 O O . HOH G 5 . ? 60.888 45.608 -24.627 1.00 35.67 ? 1294 HOH A O 1 HETATM 8855 O O . HOH G 5 . ? 61.319 43.925 -22.848 1.00 40.68 ? 1295 HOH A O 1 HETATM 8856 O O . HOH G 5 . ? 62.947 42.752 -20.858 1.00 30.68 ? 1296 HOH A O 1 HETATM 8857 O O . HOH G 5 . ? 58.164 41.144 -21.475 1.00 36.10 ? 1297 HOH A O 1 HETATM 8858 O O . HOH G 5 . ? 57.176 43.086 -19.965 1.00 21.32 ? 1298 HOH A O 1 HETATM 8859 O O . HOH G 5 . ? 54.532 40.833 -20.417 1.00 35.49 ? 1299 HOH A O 1 HETATM 8860 O O . HOH G 5 . ? 54.357 38.224 -20.084 1.00 41.93 ? 1300 HOH A O 1 HETATM 8861 O O . HOH G 5 . ? 57.061 39.016 -19.283 1.00 32.04 ? 1301 HOH A O 1 HETATM 8862 O O . HOH G 5 . ? 58.310 37.322 -17.767 1.00 39.00 ? 1302 HOH A O 1 HETATM 8863 O O . HOH G 5 . ? 59.286 37.633 -15.284 1.00 24.27 ? 1303 HOH A O 1 HETATM 8864 O O . HOH G 5 . ? 57.177 36.028 -14.274 1.00 31.04 ? 1304 HOH A O 1 HETATM 8865 O O . HOH G 5 . ? 58.604 34.853 -12.276 1.00 29.76 ? 1305 HOH A O 1 HETATM 8866 O O . HOH G 5 . ? 57.719 34.262 -10.024 1.00 38.88 ? 1306 HOH A O 1 HETATM 8867 O O . HOH G 5 . ? 58.218 34.739 -6.249 1.00 30.67 ? 1307 HOH A O 1 HETATM 8868 O O . HOH G 5 . ? 55.663 34.393 -4.748 1.00 35.29 ? 1308 HOH A O 1 HETATM 8869 O O . HOH G 5 . ? 52.450 36.730 -3.015 1.00 34.33 ? 1309 HOH A O 1 HETATM 8870 O O . HOH G 5 . ? 48.768 39.227 -3.483 1.00 33.16 ? 1310 HOH A O 1 HETATM 8871 O O . HOH G 5 . ? 48.481 40.829 -1.044 1.00 25.28 ? 1311 HOH A O 1 HETATM 8872 O O . HOH G 5 . ? 47.480 42.853 -2.292 1.00 15.29 ? 1312 HOH A O 1 HETATM 8873 O O . HOH G 5 . ? 47.987 41.752 -5.286 1.00 26.64 ? 1313 HOH A O 1 HETATM 8874 O O . HOH G 5 . ? 45.471 41.465 -6.049 1.00 30.10 ? 1314 HOH A O 1 HETATM 8875 O O . HOH G 5 . ? 43.551 41.761 -7.538 1.00 23.86 ? 1315 HOH A O 1 HETATM 8876 O O . HOH G 5 . ? 45.713 42.168 -8.991 1.00 37.77 ? 1316 HOH A O 1 HETATM 8877 O O . HOH G 5 . ? 48.045 43.920 -8.546 1.00 17.18 ? 1317 HOH A O 1 HETATM 8878 O O . HOH G 5 . ? 48.777 44.181 -6.118 1.00 13.47 ? 1318 HOH A O 1 HETATM 8879 O O . HOH G 5 . ? 51.045 44.219 -7.929 1.00 9.33 ? 1319 HOH A O 1 HETATM 8880 O O . HOH G 5 . ? 49.516 41.499 -10.581 1.00 43.08 ? 1320 HOH A O 1 HETATM 8881 O O . HOH G 5 . ? 48.097 41.658 -12.524 1.00 41.50 ? 1321 HOH A O 1 HETATM 8882 O O . HOH G 5 . ? 47.467 41.248 -14.815 1.00 22.73 ? 1322 HOH A O 1 HETATM 8883 O O . HOH G 5 . ? 45.186 39.267 -14.090 1.00 39.72 ? 1323 HOH A O 1 HETATM 8884 O O . HOH G 5 . ? 42.664 39.329 -15.826 1.00 23.59 ? 1324 HOH A O 1 HETATM 8885 O O . HOH G 5 . ? 41.669 41.132 -17.620 1.00 18.52 ? 1325 HOH A O 1 HETATM 8886 O O . HOH G 5 . ? 41.008 40.692 -21.503 1.00 25.07 ? 1326 HOH A O 1 HETATM 8887 O O . HOH G 5 . ? 43.321 40.540 -22.933 1.00 30.75 ? 1327 HOH A O 1 HETATM 8888 O O . HOH G 5 . ? 43.598 42.854 -24.747 1.00 24.44 ? 1328 HOH A O 1 HETATM 8889 O O . HOH G 5 . ? 41.501 44.684 -24.245 1.00 22.26 ? 1329 HOH A O 1 HETATM 8890 O O . HOH G 5 . ? 40.128 45.380 -26.503 1.00 35.28 ? 1330 HOH A O 1 HETATM 8891 O O . HOH G 5 . ? 37.392 45.261 -25.389 1.00 20.21 ? 1331 HOH A O 1 HETATM 8892 O O . HOH G 5 . ? 35.646 45.142 -27.384 1.00 15.74 ? 1332 HOH A O 1 HETATM 8893 O O . HOH G 5 . ? 36.134 41.663 -26.736 1.00 34.45 ? 1333 HOH A O 1 HETATM 8894 O O . HOH G 5 . ? 37.141 41.166 -24.357 1.00 29.21 ? 1334 HOH A O 1 HETATM 8895 O O . HOH G 5 . ? 38.715 42.095 -22.090 1.00 22.35 ? 1335 HOH A O 1 HETATM 8896 O O . HOH G 5 . ? 43.387 46.092 -22.688 1.00 32.70 ? 1336 HOH A O 1 HETATM 8897 O O . HOH G 5 . ? 42.226 47.328 -24.548 1.00 14.52 ? 1337 HOH A O 1 HETATM 8898 O O . HOH G 5 . ? 42.810 47.299 -27.209 1.00 33.99 ? 1338 HOH A O 1 HETATM 8899 O O . HOH G 5 . ? 45.151 48.566 -27.095 1.00 72.54 ? 1339 HOH A O 1 HETATM 8900 O O . HOH G 5 . ? 41.132 48.389 -29.278 1.00 36.13 ? 1340 HOH A O 1 HETATM 8901 O O . HOH G 5 . ? 38.862 51.323 -29.794 1.00 25.75 ? 1341 HOH A O 1 HETATM 8902 O O . HOH G 5 . ? 39.514 48.583 -32.813 1.00 26.82 ? 1342 HOH A O 1 HETATM 8903 O O . HOH G 5 . ? 38.638 45.110 -33.605 1.00 25.98 ? 1343 HOH A O 1 HETATM 8904 O O . HOH G 5 . ? 42.202 45.223 -33.009 1.00 43.65 ? 1344 HOH A O 1 HETATM 8905 O O . HOH G 5 . ? 48.035 48.970 -31.196 1.00 32.13 ? 1345 HOH A O 1 HETATM 8906 O O . HOH G 5 . ? 49.091 50.680 -29.464 1.00 20.57 ? 1346 HOH A O 1 HETATM 8907 O O . HOH G 5 . ? 49.907 46.602 -30.330 1.00 34.08 ? 1347 HOH A O 1 HETATM 8908 O O . HOH G 5 . ? 52.506 45.272 -27.149 1.00 31.91 ? 1348 HOH A O 1 HETATM 8909 O O . HOH G 5 . ? 53.317 47.097 -24.990 1.00 17.21 ? 1349 HOH A O 1 HETATM 8910 O O . HOH G 5 . ? 56.318 50.026 -30.038 1.00 31.48 ? 1350 HOH A O 1 HETATM 8911 O O . HOH G 5 . ? 59.426 44.628 -30.538 1.00 34.59 ? 1351 HOH A O 1 HETATM 8912 O O . HOH G 5 . ? 58.587 43.866 -27.960 1.00 37.95 ? 1352 HOH A O 1 HETATM 8913 O O . HOH G 5 . ? 61.361 47.328 -26.702 1.00 41.87 ? 1353 HOH A O 1 HETATM 8914 O O . HOH G 5 . ? 58.648 53.785 -22.080 1.00 21.79 ? 1354 HOH A O 1 HETATM 8915 O O . HOH G 5 . ? 51.331 53.266 -23.816 1.00 12.60 ? 1355 HOH A O 1 HETATM 8916 O O . HOH G 5 . ? 48.717 54.907 -22.606 1.00 22.54 ? 1356 HOH A O 1 HETATM 8917 O O . HOH G 5 . ? 46.746 53.843 -21.211 1.00 27.05 ? 1357 HOH A O 1 HETATM 8918 O O . HOH G 5 . ? 46.005 52.708 -19.056 1.00 16.52 ? 1358 HOH A O 1 HETATM 8919 O O . HOH G 5 . ? 45.202 54.993 -18.088 1.00 24.14 ? 1359 HOH A O 1 HETATM 8920 O O A HOH G 5 . ? 42.497 54.578 -17.501 0.50 17.73 ? 1360 HOH A O 1 HETATM 8921 O O B HOH G 5 . ? 41.146 54.711 -17.172 0.50 12.69 ? 1360 HOH A O 1 HETATM 8922 O O . HOH G 5 . ? 41.089 52.192 -16.880 1.00 10.82 ? 1361 HOH A O 1 HETATM 8923 O O . HOH G 5 . ? 38.503 54.225 -17.451 1.00 28.52 ? 1362 HOH A O 1 HETATM 8924 O O . HOH G 5 . ? 37.651 56.635 -16.501 1.00 43.44 ? 1363 HOH A O 1 HETATM 8925 O O A HOH G 5 . ? 39.747 58.750 -17.986 0.50 14.42 ? 1364 HOH A O 1 HETATM 8926 O O B HOH G 5 . ? 38.609 58.425 -18.868 0.50 14.48 ? 1364 HOH A O 1 HETATM 8927 O O . HOH G 5 . ? 41.733 58.577 -15.973 1.00 17.38 ? 1365 HOH A O 1 HETATM 8928 O O . HOH G 5 . ? 44.566 58.582 -15.929 1.00 20.41 ? 1366 HOH A O 1 HETATM 8929 O O . HOH G 5 . ? 44.524 56.076 -15.350 1.00 18.16 ? 1367 HOH A O 1 HETATM 8930 O O . HOH G 5 . ? 47.312 55.662 -15.416 1.00 16.40 ? 1368 HOH A O 1 HETATM 8931 O O . HOH G 5 . ? 46.710 57.317 -18.759 1.00 13.56 ? 1369 HOH A O 1 HETATM 8932 O O . HOH G 5 . ? 45.695 59.896 -18.221 1.00 16.74 ? 1370 HOH A O 1 HETATM 8933 O O . HOH G 5 . ? 42.863 59.273 -18.679 1.00 22.56 ? 1371 HOH A O 1 HETATM 8934 O O . HOH G 5 . ? 40.339 56.073 -19.282 1.00 24.48 ? 1372 HOH A O 1 HETATM 8935 O O . HOH G 5 . ? 39.675 53.874 -20.683 1.00 13.47 ? 1373 HOH A O 1 HETATM 8936 O O . HOH G 5 . ? 37.686 52.059 -21.087 1.00 9.62 ? 1374 HOH A O 1 HETATM 8937 O O . HOH G 5 . ? 37.622 51.392 -18.557 1.00 14.54 ? 1375 HOH A O 1 HETATM 8938 O O . HOH G 5 . ? 35.190 50.518 -17.606 1.00 11.17 ? 1376 HOH A O 1 HETATM 8939 O O . HOH G 5 . ? 35.102 48.178 -16.416 1.00 22.03 ? 1377 HOH A O 1 HETATM 8940 O O . HOH G 5 . ? 33.561 48.018 -10.136 1.00 6.55 ? 1378 HOH A O 1 HETATM 8941 O O . HOH G 5 . ? 31.766 46.924 -8.096 1.00 5.67 ? 1379 HOH A O 1 HETATM 8942 O O . HOH G 5 . ? 36.710 44.809 -5.500 1.00 9.63 ? 1380 HOH A O 1 HETATM 8943 O O . HOH G 5 . ? 41.499 44.610 -6.802 1.00 13.20 ? 1381 HOH A O 1 HETATM 8944 O O . HOH G 5 . ? 42.024 40.332 -9.886 1.00 38.49 ? 1382 HOH A O 1 HETATM 8945 O O . HOH G 5 . ? 39.283 37.991 -10.870 1.00 33.52 ? 1383 HOH A O 1 HETATM 8946 O O . HOH G 5 . ? 41.112 36.375 -12.813 1.00 41.51 ? 1384 HOH A O 1 HETATM 8947 O O . HOH G 5 . ? 36.692 35.013 -15.927 1.00 30.37 ? 1385 HOH A O 1 HETATM 8948 O O . HOH G 5 . ? 37.291 35.425 -18.805 1.00 37.64 ? 1386 HOH A O 1 HETATM 8949 O O . HOH G 5 . ? 34.567 35.402 -22.353 1.00 38.78 ? 1387 HOH A O 1 HETATM 8950 O O . HOH G 5 . ? 33.559 38.913 -19.534 1.00 23.89 ? 1388 HOH A O 1 HETATM 8951 O O . HOH G 5 . ? 33.012 40.895 -17.757 1.00 19.60 ? 1389 HOH A O 1 HETATM 8952 O O . HOH G 5 . ? 35.873 39.047 -16.055 1.00 23.71 ? 1390 HOH A O 1 HETATM 8953 O O . HOH G 5 . ? 39.939 42.946 -12.736 1.00 41.38 ? 1391 HOH A O 1 HETATM 8954 O O . HOH G 5 . ? 43.147 38.255 -5.866 1.00 32.78 ? 1392 HOH A O 1 HETATM 8955 O O . HOH G 5 . ? 39.887 38.648 -3.419 1.00 23.38 ? 1393 HOH A O 1 HETATM 8956 O O . HOH G 5 . ? 38.985 36.283 -3.711 1.00 33.34 ? 1394 HOH A O 1 HETATM 8957 O O . HOH G 5 . ? 36.480 35.872 -1.984 1.00 42.37 ? 1395 HOH A O 1 HETATM 8958 O O . HOH G 5 . ? 35.996 35.960 -4.636 1.00 22.30 ? 1396 HOH A O 1 HETATM 8959 O O . HOH G 5 . ? 33.297 36.561 -4.458 1.00 14.45 ? 1397 HOH A O 1 HETATM 8960 O O . HOH G 5 . ? 32.294 39.045 -4.925 1.00 8.59 ? 1398 HOH A O 1 HETATM 8961 O O . HOH G 5 . ? 32.175 34.326 -3.202 1.00 22.43 ? 1399 HOH A O 1 HETATM 8962 O O . HOH G 5 . ? 30.165 34.061 -1.353 1.00 29.37 ? 1400 HOH A O 1 HETATM 8963 O O . HOH G 5 . ? 31.227 33.541 2.694 1.00 21.28 ? 1401 HOH A O 1 HETATM 8964 O O . HOH G 5 . ? 31.108 29.884 5.546 1.00 35.15 ? 1402 HOH A O 1 HETATM 8965 O O . HOH G 5 . ? 24.710 32.880 6.300 1.00 24.64 ? 1403 HOH A O 1 HETATM 8966 O O . HOH G 5 . ? 23.084 31.549 3.947 1.00 38.50 ? 1404 HOH A O 1 HETATM 8967 O O . HOH G 5 . ? 22.552 34.174 1.174 1.00 35.38 ? 1405 HOH A O 1 HETATM 8968 O O . HOH G 5 . ? 22.084 36.691 0.119 1.00 22.05 ? 1406 HOH A O 1 HETATM 8969 O O . HOH G 5 . ? 19.671 37.198 1.451 1.00 37.08 ? 1407 HOH A O 1 HETATM 8970 O O . HOH G 5 . ? 17.914 37.439 -0.136 1.00 35.92 ? 1408 HOH A O 1 HETATM 8971 O O . HOH G 5 . ? 18.032 39.671 -2.902 1.00 40.95 ? 1409 HOH A O 1 HETATM 8972 O O . HOH G 5 . ? 20.074 38.885 -3.664 1.00 27.51 ? 1410 HOH A O 1 HETATM 8973 O O . HOH G 5 . ? 19.752 41.421 -4.972 1.00 27.07 ? 1411 HOH A O 1 HETATM 8974 O O . HOH G 5 . ? 20.879 42.418 -7.507 1.00 23.90 ? 1412 HOH A O 1 HETATM 8975 O O . HOH G 5 . ? 19.755 40.948 -9.710 1.00 30.11 ? 1413 HOH A O 1 HETATM 8976 O O . HOH G 5 . ? 22.440 40.005 -9.639 1.00 40.00 ? 1414 HOH A O 1 HETATM 8977 O O . HOH G 5 . ? 24.120 39.069 -11.290 1.00 21.71 ? 1415 HOH A O 1 HETATM 8978 O O . HOH G 5 . ? 21.900 38.211 -12.132 1.00 38.42 ? 1416 HOH A O 1 HETATM 8979 O O . HOH G 5 . ? 19.689 39.872 -12.886 1.00 46.49 ? 1417 HOH A O 1 HETATM 8980 O O . HOH G 5 . ? 17.581 39.868 -15.283 1.00 38.08 ? 1418 HOH A O 1 HETATM 8981 O O . HOH G 5 . ? 20.168 42.144 -15.222 1.00 43.38 ? 1419 HOH A O 1 HETATM 8982 O O . HOH G 5 . ? 21.329 44.937 -15.557 1.00 39.69 ? 1420 HOH A O 1 HETATM 8983 O O . HOH G 5 . ? 21.096 46.485 -17.552 1.00 36.21 ? 1421 HOH A O 1 HETATM 8984 O O . HOH G 5 . ? 23.609 45.997 -16.012 1.00 27.05 ? 1422 HOH A O 1 HETATM 8985 O O . HOH G 5 . ? 22.989 45.189 -13.565 1.00 28.42 ? 1423 HOH A O 1 HETATM 8986 O O . HOH G 5 . ? 24.433 42.352 -14.337 1.00 19.00 ? 1424 HOH A O 1 HETATM 8987 O O . HOH G 5 . ? 26.819 41.539 -13.270 1.00 11.30 ? 1425 HOH A O 1 HETATM 8988 O O . HOH G 5 . ? 28.953 42.642 -11.960 1.00 9.05 ? 1426 HOH A O 1 HETATM 8989 O O . HOH G 5 . ? 26.331 48.818 -11.006 1.00 8.06 ? 1427 HOH A O 1 HETATM 8990 O O . HOH G 5 . ? 26.188 49.487 -13.731 1.00 7.04 ? 1428 HOH A O 1 HETATM 8991 O O . HOH G 5 . ? 24.740 52.821 -11.801 1.00 8.41 ? 1429 HOH A O 1 HETATM 8992 O O . HOH G 5 . ? 22.361 54.371 -12.039 1.00 8.13 ? 1430 HOH A O 1 HETATM 8993 O O . HOH G 5 . ? 19.715 53.399 -11.818 1.00 10.38 ? 1431 HOH A O 1 HETATM 8994 O O . HOH G 5 . ? 18.703 50.933 -12.512 1.00 10.00 ? 1432 HOH A O 1 HETATM 8995 O O . HOH G 5 . ? 19.753 46.832 -14.449 1.00 18.31 ? 1433 HOH A O 1 HETATM 8996 O O . HOH G 5 . ? 17.576 45.385 -14.314 1.00 28.27 ? 1434 HOH A O 1 HETATM 8997 O O . HOH G 5 . ? 16.236 44.601 -11.691 1.00 23.98 ? 1435 HOH A O 1 HETATM 8998 O O . HOH G 5 . ? 13.728 45.896 -12.457 1.00 33.47 ? 1436 HOH A O 1 HETATM 8999 O O . HOH G 5 . ? 11.577 45.628 -11.949 1.00 42.94 ? 1437 HOH A O 1 HETATM 9000 O O . HOH G 5 . ? 12.893 51.446 -12.105 1.00 27.18 ? 1438 HOH A O 1 HETATM 9001 O O . HOH G 5 . ? 13.157 52.052 -15.068 1.00 29.97 ? 1439 HOH A O 1 HETATM 9002 O O . HOH G 5 . ? 14.380 54.094 -16.306 1.00 16.89 ? 1440 HOH A O 1 HETATM 9003 O O . HOH G 5 . ? 12.284 55.371 -15.113 1.00 17.47 ? 1441 HOH A O 1 HETATM 9004 O O . HOH G 5 . ? 11.828 54.714 -12.377 1.00 16.78 ? 1442 HOH A O 1 HETATM 9005 O O . HOH G 5 . ? 9.344 53.804 -12.189 1.00 37.20 ? 1443 HOH A O 1 HETATM 9006 O O . HOH G 5 . ? 7.996 57.231 -11.511 1.00 43.09 ? 1444 HOH A O 1 HETATM 9007 O O . HOH G 5 . ? 7.246 56.716 -9.065 1.00 37.12 ? 1445 HOH A O 1 HETATM 9008 O O A HOH G 5 . ? 8.653 57.670 -6.934 0.50 17.38 ? 1446 HOH A O 1 HETATM 9009 O O B HOH G 5 . ? 9.938 56.892 -5.788 0.50 14.35 ? 1446 HOH A O 1 HETATM 9010 O O . HOH G 5 . ? 8.789 54.992 -6.125 1.00 28.66 ? 1447 HOH A O 1 HETATM 9011 O O . HOH G 5 . ? 10.185 58.047 -3.376 1.00 31.25 ? 1448 HOH A O 1 HETATM 9012 O O . HOH G 5 . ? 11.987 59.267 -5.008 1.00 18.81 ? 1449 HOH A O 1 HETATM 9013 O O . HOH G 5 . ? 14.186 59.569 -3.438 1.00 12.44 ? 1450 HOH A O 1 HETATM 9014 O O . HOH G 5 . ? 13.000 61.794 -2.552 1.00 27.25 ? 1451 HOH A O 1 HETATM 9015 O O . HOH G 5 . ? 11.385 62.478 -4.519 1.00 33.41 ? 1452 HOH A O 1 HETATM 9016 O O . HOH G 5 . ? 10.979 65.030 -5.491 1.00 34.65 ? 1453 HOH A O 1 HETATM 9017 O O . HOH G 5 . ? 13.158 66.575 -4.890 1.00 12.40 ? 1454 HOH A O 1 HETATM 9018 O O . HOH G 5 . ? 14.122 68.030 -7.866 1.00 18.60 ? 1455 HOH A O 1 HETATM 9019 O O . HOH G 5 . ? 13.563 69.664 -9.679 1.00 28.27 ? 1456 HOH A O 1 HETATM 9020 O O . HOH G 5 . ? 12.423 68.138 -11.538 1.00 23.74 ? 1457 HOH A O 1 HETATM 9021 O O . HOH G 5 . ? 12.782 66.835 -13.721 1.00 23.16 ? 1458 HOH A O 1 HETATM 9022 O O . HOH G 5 . ? 14.623 66.202 -15.493 1.00 19.46 ? 1459 HOH A O 1 HETATM 9023 O O . HOH G 5 . ? 14.435 63.834 -16.437 1.00 16.92 ? 1460 HOH A O 1 HETATM 9024 O O . HOH G 5 . ? 14.620 61.847 -14.490 1.00 24.54 ? 1461 HOH A O 1 HETATM 9025 O O . HOH G 5 . ? 14.296 62.636 -12.250 1.00 25.84 ? 1462 HOH A O 1 HETATM 9026 O O . HOH G 5 . ? 10.771 62.235 -11.986 1.00 30.84 ? 1463 HOH A O 1 HETATM 9027 O O . HOH G 5 . ? 10.582 64.274 -10.448 1.00 36.19 ? 1464 HOH A O 1 HETATM 9028 O O . HOH G 5 . ? 12.733 66.062 -9.866 1.00 18.25 ? 1465 HOH A O 1 HETATM 9029 O O . HOH G 5 . ? 10.323 69.956 -10.182 1.00 32.75 ? 1466 HOH A O 1 HETATM 9030 O O . HOH G 5 . ? 12.454 74.987 -13.222 1.00 25.39 ? 1467 HOH A O 1 HETATM 9031 O O . HOH G 5 . ? 15.854 75.066 -11.729 1.00 15.70 ? 1468 HOH A O 1 HETATM 9032 O O . HOH G 5 . ? 15.646 77.090 -13.725 1.00 29.94 ? 1469 HOH A O 1 HETATM 9033 O O . HOH G 5 . ? 15.297 79.604 -11.561 1.00 38.43 ? 1470 HOH A O 1 HETATM 9034 O O . HOH G 5 . ? 15.590 81.006 -9.516 1.00 49.83 ? 1471 HOH A O 1 HETATM 9035 O O . HOH G 5 . ? 17.221 80.624 -7.394 1.00 21.25 ? 1472 HOH A O 1 HETATM 9036 O O . HOH G 5 . ? 16.743 81.915 -4.976 1.00 31.16 ? 1473 HOH A O 1 HETATM 9037 O O . HOH G 5 . ? 18.047 84.255 -5.129 1.00 30.08 ? 1474 HOH A O 1 HETATM 9038 O O . HOH G 5 . ? 19.608 84.284 -1.014 1.00 39.27 ? 1475 HOH A O 1 HETATM 9039 O O . HOH G 5 . ? 21.060 86.274 -2.366 1.00 39.20 ? 1476 HOH A O 1 HETATM 9040 O O . HOH G 5 . ? 24.512 86.865 -1.035 1.00 32.38 ? 1477 HOH A O 1 HETATM 9041 O O . HOH G 5 . ? 26.334 88.117 0.796 1.00 38.67 ? 1478 HOH A O 1 HETATM 9042 O O . HOH G 5 . ? 22.628 88.967 2.789 1.00 29.22 ? 1479 HOH A O 1 HETATM 9043 O O . HOH G 5 . ? 24.704 83.827 2.510 1.00 25.82 ? 1480 HOH A O 1 HETATM 9044 O O . HOH G 5 . ? 27.311 82.134 3.151 1.00 26.25 ? 1481 HOH A O 1 HETATM 9045 O O . HOH G 5 . ? 29.773 82.977 2.416 1.00 18.09 ? 1482 HOH A O 1 HETATM 9046 O O . HOH G 5 . ? 30.679 83.235 4.787 1.00 30.61 ? 1483 HOH A O 1 HETATM 9047 O O . HOH G 5 . ? 30.164 82.576 7.071 1.00 28.73 ? 1484 HOH A O 1 HETATM 9048 O O . HOH G 5 . ? 31.990 80.334 7.237 1.00 24.35 ? 1485 HOH A O 1 HETATM 9049 O O . HOH G 5 . ? 35.895 80.908 6.322 1.00 15.48 ? 1486 HOH A O 1 HETATM 9050 O O . HOH G 5 . ? 33.555 83.661 3.326 1.00 36.22 ? 1487 HOH A O 1 HETATM 9051 O O . HOH G 5 . ? 32.639 84.202 0.379 1.00 30.50 ? 1488 HOH A O 1 HETATM 9052 O O . HOH G 5 . ? 35.329 84.870 -0.649 1.00 34.72 ? 1489 HOH A O 1 HETATM 9053 O O . HOH G 5 . ? 38.080 83.086 -1.058 1.00 26.02 ? 1490 HOH A O 1 HETATM 9054 O O . HOH G 5 . ? 37.570 80.476 -0.614 1.00 21.35 ? 1491 HOH A O 1 HETATM 9055 O O . HOH G 5 . ? 38.876 80.204 -2.976 1.00 32.56 ? 1492 HOH A O 1 HETATM 9056 O O . HOH G 5 . ? 40.942 81.847 -3.709 1.00 28.50 ? 1493 HOH A O 1 HETATM 9057 O O . HOH G 5 . ? 37.294 83.377 -4.103 1.00 26.93 ? 1494 HOH A O 1 HETATM 9058 O O . HOH G 5 . ? 36.232 79.160 -5.029 1.00 23.74 ? 1495 HOH A O 1 HETATM 9059 O O . HOH G 5 . ? 35.718 77.543 -7.357 1.00 13.10 ? 1496 HOH A O 1 HETATM 9060 O O . HOH G 5 . ? 34.513 79.024 -9.193 1.00 10.81 ? 1497 HOH A O 1 HETATM 9061 O O . HOH G 5 . ? 32.738 80.947 -11.695 1.00 9.96 ? 1498 HOH A O 1 HETATM 9062 O O . HOH G 5 . ? 33.535 83.440 -10.418 1.00 14.11 ? 1499 HOH A O 1 HETATM 9063 O O . HOH G 5 . ? 32.057 85.163 -8.624 1.00 21.83 ? 1500 HOH A O 1 HETATM 9064 O O . HOH G 5 . ? 32.853 85.242 -5.639 1.00 17.67 ? 1501 HOH A O 1 HETATM 9065 O O . HOH G 5 . ? 31.064 86.875 -2.829 1.00 29.83 ? 1502 HOH A O 1 HETATM 9066 O O . HOH G 5 . ? 26.699 87.736 -4.017 1.00 39.16 ? 1503 HOH A O 1 HETATM 9067 O O . HOH G 5 . ? 24.150 82.739 -4.144 1.00 31.99 ? 1504 HOH A O 1 HETATM 9068 O O . HOH G 5 . ? 21.296 78.385 -1.326 1.00 16.36 ? 1505 HOH A O 1 HETATM 9069 O O . HOH G 5 . ? 19.472 80.189 -1.061 1.00 34.48 ? 1506 HOH A O 1 HETATM 9070 O O . HOH G 5 . ? 16.093 80.365 -1.308 1.00 42.12 ? 1507 HOH A O 1 HETATM 9071 O O . HOH G 5 . ? 13.688 77.484 0.714 1.00 29.40 ? 1508 HOH A O 1 HETATM 9072 O O . HOH G 5 . ? 10.294 76.405 3.873 1.00 35.64 ? 1509 HOH A O 1 HETATM 9073 O O . HOH G 5 . ? 6.769 80.177 2.189 1.00 34.81 ? 1510 HOH A O 1 HETATM 9074 O O . HOH G 5 . ? 8.972 81.386 -5.284 1.00 32.65 ? 1511 HOH A O 1 HETATM 9075 O O . HOH G 5 . ? 10.559 77.206 -5.272 1.00 31.05 ? 1512 HOH A O 1 HETATM 9076 O O . HOH G 5 . ? 9.862 75.367 -3.268 1.00 32.23 ? 1513 HOH A O 1 HETATM 9077 O O . HOH G 5 . ? 12.564 70.807 -0.406 1.00 20.01 ? 1514 HOH A O 1 HETATM 9078 O O . HOH G 5 . ? 13.239 68.463 0.812 1.00 16.70 ? 1515 HOH A O 1 HETATM 9079 O O . HOH G 5 . ? 11.670 66.613 3.050 1.00 31.50 ? 1516 HOH A O 1 HETATM 9080 O O . HOH G 5 . ? 9.805 64.434 4.685 1.00 36.57 ? 1517 HOH A O 1 HETATM 9081 O O . HOH G 5 . ? 11.562 62.195 5.543 1.00 40.35 ? 1518 HOH A O 1 HETATM 9082 O O . HOH G 5 . ? 13.698 60.782 7.681 1.00 23.35 ? 1519 HOH A O 1 HETATM 9083 O O . HOH G 5 . ? 14.422 59.845 5.124 1.00 9.89 ? 1520 HOH A O 1 HETATM 9084 O O . HOH G 5 . ? 11.686 58.531 7.702 1.00 24.13 ? 1521 HOH A O 1 HETATM 9085 O O . HOH G 5 . ? 9.794 59.467 6.311 1.00 31.94 ? 1522 HOH A O 1 HETATM 9086 O O . HOH G 5 . ? 7.086 60.464 7.412 1.00 36.70 ? 1523 HOH A O 1 HETATM 9087 O O . HOH G 5 . ? 5.400 57.145 6.740 1.00 31.94 ? 1524 HOH A O 1 HETATM 9088 O O . HOH G 5 . ? 3.758 54.699 5.648 1.00 37.22 ? 1525 HOH A O 1 HETATM 9089 O O . HOH G 5 . ? 6.854 59.423 2.488 1.00 40.52 ? 1526 HOH A O 1 HETATM 9090 O O . HOH G 5 . ? 8.030 58.268 -0.231 1.00 36.03 ? 1527 HOH A O 1 HETATM 9091 O O . HOH G 5 . ? 11.133 61.044 -0.752 1.00 37.35 ? 1528 HOH A O 1 HETATM 9092 O O . HOH G 5 . ? 10.390 62.123 1.745 1.00 28.54 ? 1529 HOH A O 1 HETATM 9093 O O . HOH G 5 . ? 14.021 64.494 6.281 1.00 31.30 ? 1530 HOH A O 1 HETATM 9094 O O . HOH G 5 . ? 14.299 68.657 5.440 1.00 33.22 ? 1531 HOH A O 1 HETATM 9095 O O . HOH G 5 . ? 16.074 70.007 6.295 1.00 36.37 ? 1532 HOH A O 1 HETATM 9096 O O . HOH G 5 . ? 18.542 69.795 4.115 1.00 12.28 ? 1533 HOH A O 1 HETATM 9097 O O . HOH G 5 . ? 19.208 72.213 2.991 1.00 13.23 ? 1534 HOH A O 1 HETATM 9098 O O . HOH G 5 . ? 17.679 74.289 3.765 1.00 17.93 ? 1535 HOH A O 1 HETATM 9099 O O . HOH G 5 . ? 19.175 76.371 4.751 1.00 22.63 ? 1536 HOH A O 1 HETATM 9100 O O . HOH G 5 . ? 19.446 76.119 7.409 1.00 42.49 ? 1537 HOH A O 1 HETATM 9101 O O . HOH G 5 . ? 21.918 76.384 8.750 1.00 26.20 ? 1538 HOH A O 1 HETATM 9102 O O . HOH G 5 . ? 25.038 73.591 8.886 1.00 22.50 ? 1539 HOH A O 1 HETATM 9103 O O . HOH G 5 . ? 26.261 74.809 11.086 1.00 26.81 ? 1540 HOH A O 1 HETATM 9104 O O . HOH G 5 . ? 29.380 75.388 10.959 1.00 26.20 ? 1541 HOH A O 1 HETATM 9105 O O . HOH G 5 . ? 30.074 77.848 11.343 1.00 38.73 ? 1542 HOH A O 1 HETATM 9106 O O . HOH G 5 . ? 32.212 78.233 12.755 1.00 44.34 ? 1543 HOH A O 1 HETATM 9107 O O . HOH G 5 . ? 34.693 77.410 12.397 1.00 27.96 ? 1544 HOH A O 1 HETATM 9108 O O . HOH G 5 . ? 28.412 63.398 13.804 1.00 33.79 ? 1545 HOH A O 1 HETATM 9109 O O . HOH G 5 . ? 25.887 63.036 13.313 1.00 31.69 ? 1546 HOH A O 1 HETATM 9110 O O . HOH G 5 . ? 23.571 62.343 13.682 1.00 36.20 ? 1547 HOH A O 1 HETATM 9111 O O . HOH G 5 . ? 21.274 63.395 14.446 1.00 28.83 ? 1548 HOH A O 1 HETATM 9112 O O . HOH G 5 . ? 22.642 62.415 16.158 1.00 25.55 ? 1549 HOH A O 1 HETATM 9113 O O A HOH G 5 . ? 23.296 64.595 18.115 0.50 22.46 ? 1550 HOH A O 1 HETATM 9114 O O B HOH G 5 . ? 23.536 66.035 18.768 0.50 22.55 ? 1550 HOH A O 1 HETATM 9115 O O . HOH G 5 . ? 25.525 65.847 17.237 1.00 24.44 ? 1551 HOH A O 1 HETATM 9116 O O . HOH G 5 . ? 26.357 63.596 16.982 1.00 15.77 ? 1552 HOH A O 1 HETATM 9117 O O . HOH G 5 . ? 28.557 65.109 19.648 1.00 15.31 ? 1553 HOH A O 1 HETATM 9118 O O . HOH G 5 . ? 26.219 66.693 19.702 1.00 26.13 ? 1554 HOH A O 1 HETATM 9119 O O . HOH G 5 . ? 24.745 68.185 21.713 1.00 18.83 ? 1555 HOH A O 1 HETATM 9120 O O . HOH G 5 . ? 22.486 67.955 20.234 1.00 22.10 ? 1556 HOH A O 1 HETATM 9121 O O . HOH G 5 . ? 20.504 68.197 22.002 1.00 23.36 ? 1557 HOH A O 1 HETATM 9122 O O . HOH G 5 . ? 17.652 68.277 24.064 1.00 38.60 ? 1558 HOH A O 1 HETATM 9123 O O . HOH G 5 . ? 15.609 68.397 22.000 1.00 36.41 ? 1559 HOH A O 1 HETATM 9124 O O . HOH G 5 . ? 15.040 69.889 24.137 1.00 34.10 ? 1560 HOH A O 1 HETATM 9125 O O . HOH G 5 . ? 12.749 70.319 25.161 1.00 33.67 ? 1561 HOH A O 1 HETATM 9126 O O . HOH G 5 . ? 17.717 65.995 27.817 1.00 19.98 ? 1562 HOH A O 1 HETATM 9127 O O . HOH G 5 . ? 20.356 65.592 27.182 1.00 24.64 ? 1563 HOH A O 1 HETATM 9128 O O A HOH G 5 . ? 22.433 65.729 29.514 0.50 20.85 ? 1564 HOH A O 1 HETATM 9129 O O B HOH G 5 . ? 22.276 66.880 28.776 0.50 12.43 ? 1564 HOH A O 1 HETATM 9130 O O . HOH G 5 . ? 22.220 65.337 32.360 1.00 26.05 ? 1565 HOH A O 1 HETATM 9131 O O . HOH G 5 . ? 22.245 62.568 33.779 1.00 24.60 ? 1566 HOH A O 1 HETATM 9132 O O . HOH G 5 . ? 19.557 62.444 34.691 1.00 30.08 ? 1567 HOH A O 1 HETATM 9133 O O . HOH G 5 . ? 17.481 61.678 33.340 1.00 34.27 ? 1568 HOH A O 1 HETATM 9134 O O . HOH G 5 . ? 18.106 59.641 31.759 1.00 29.85 ? 1569 HOH A O 1 HETATM 9135 O O . HOH G 5 . ? 16.138 57.401 31.301 1.00 40.58 ? 1570 HOH A O 1 HETATM 9136 O O . HOH G 5 . ? 14.667 55.380 27.221 1.00 27.68 ? 1571 HOH A O 1 HETATM 9137 O O . HOH G 5 . ? 12.892 55.004 24.946 1.00 40.46 ? 1572 HOH A O 1 HETATM 9138 O O . HOH G 5 . ? 13.407 52.569 25.945 1.00 24.03 ? 1573 HOH A O 1 HETATM 9139 O O . HOH G 5 . ? 14.058 50.342 24.137 1.00 16.88 ? 1574 HOH A O 1 HETATM 9140 O O . HOH G 5 . ? 16.462 48.966 24.072 1.00 11.09 ? 1575 HOH A O 1 HETATM 9141 O O . HOH G 5 . ? 14.637 47.136 26.797 1.00 35.37 ? 1576 HOH A O 1 HETATM 9142 O O . HOH G 5 . ? 13.690 48.452 28.934 1.00 36.02 ? 1577 HOH A O 1 HETATM 9143 O O . HOH G 5 . ? 12.283 46.692 30.571 1.00 34.19 ? 1578 HOH A O 1 HETATM 9144 O O . HOH G 5 . ? 14.568 46.738 32.275 1.00 21.82 ? 1579 HOH A O 1 HETATM 9145 O O . HOH G 5 . ? 15.736 48.782 31.432 1.00 21.47 ? 1580 HOH A O 1 HETATM 9146 O O . HOH G 5 . ? 15.031 51.145 32.593 1.00 21.19 ? 1581 HOH A O 1 HETATM 9147 O O . HOH G 5 . ? 17.336 52.488 33.077 1.00 23.54 ? 1582 HOH A O 1 HETATM 9148 O O . HOH G 5 . ? 17.470 52.894 35.805 1.00 25.37 ? 1583 HOH A O 1 HETATM 9149 O O . HOH G 5 . ? 19.825 56.091 37.488 1.00 37.56 ? 1584 HOH A O 1 HETATM 9150 O O . HOH G 5 . ? 21.025 58.456 37.823 1.00 37.58 ? 1585 HOH A O 1 HETATM 9151 O O . HOH G 5 . ? 23.938 57.122 38.572 1.00 25.29 ? 1586 HOH A O 1 HETATM 9152 O O . HOH G 5 . ? 26.059 57.456 40.286 1.00 35.26 ? 1587 HOH A O 1 HETATM 9153 O O . HOH G 5 . ? 28.519 55.326 39.826 1.00 26.06 ? 1588 HOH A O 1 HETATM 9154 O O . HOH G 5 . ? 28.158 54.656 42.266 1.00 30.09 ? 1589 HOH A O 1 HETATM 9155 O O . HOH G 5 . ? 27.801 52.148 42.394 1.00 35.53 ? 1590 HOH A O 1 HETATM 9156 O O . HOH G 5 . ? 25.576 52.318 43.401 1.00 32.81 ? 1591 HOH A O 1 HETATM 9157 O O . HOH G 5 . ? 27.322 47.540 45.717 1.00 39.57 ? 1592 HOH A O 1 HETATM 9158 O O . HOH G 5 . ? 24.007 45.832 40.774 1.00 39.38 ? 1593 HOH A O 1 HETATM 9159 O O . HOH G 5 . ? 21.331 43.713 39.749 1.00 45.58 ? 1594 HOH A O 1 HETATM 9160 O O . HOH G 5 . ? 18.762 43.377 39.401 1.00 36.04 ? 1595 HOH A O 1 HETATM 9161 O O . HOH G 5 . ? 19.486 45.456 40.459 1.00 27.65 ? 1596 HOH A O 1 HETATM 9162 O O . HOH G 5 . ? 21.126 47.343 39.050 1.00 21.03 ? 1597 HOH A O 1 HETATM 9163 O O . HOH G 5 . ? 18.920 48.370 37.727 1.00 17.98 ? 1598 HOH A O 1 HETATM 9164 O O . HOH G 5 . ? 17.523 49.299 41.055 1.00 18.61 ? 1599 HOH A O 1 HETATM 9165 O O . HOH G 5 . ? 21.338 55.285 40.020 1.00 31.25 ? 1600 HOH A O 1 HETATM 9166 O O . HOH G 5 . ? 24.001 60.841 36.020 1.00 28.83 ? 1601 HOH A O 1 HETATM 9167 O O . HOH G 5 . ? 28.188 63.097 36.163 1.00 38.54 ? 1602 HOH A O 1 HETATM 9168 O O . HOH G 5 . ? 30.720 61.771 35.747 1.00 31.18 ? 1603 HOH A O 1 HETATM 9169 O O . HOH G 5 . ? 30.664 63.693 34.018 1.00 43.21 ? 1604 HOH A O 1 HETATM 9170 O O . HOH G 5 . ? 29.350 65.295 32.492 1.00 31.47 ? 1605 HOH A O 1 HETATM 9171 O O . HOH G 5 . ? 27.602 66.918 33.409 1.00 40.94 ? 1606 HOH A O 1 HETATM 9172 O O . HOH G 5 . ? 30.021 67.077 35.643 1.00 31.27 ? 1607 HOH A O 1 HETATM 9173 O O . HOH G 5 . ? 28.737 64.325 29.996 1.00 17.45 ? 1608 HOH A O 1 HETATM 9174 O O . HOH G 5 . ? 27.647 67.547 28.046 1.00 15.52 ? 1609 HOH A O 1 HETATM 9175 O O . HOH G 5 . ? 22.871 69.421 28.632 1.00 34.72 ? 1610 HOH A O 1 HETATM 9176 O O . HOH G 5 . ? 25.988 72.524 28.408 1.00 28.83 ? 1611 HOH A O 1 HETATM 9177 O O . HOH G 5 . ? 23.549 71.172 24.317 1.00 30.25 ? 1612 HOH A O 1 HETATM 9178 O O . HOH G 5 . ? 25.216 71.066 22.304 1.00 31.67 ? 1613 HOH A O 1 HETATM 9179 O O . HOH G 5 . ? 26.892 72.131 20.660 1.00 37.41 ? 1614 HOH A O 1 HETATM 9180 O O . HOH G 5 . ? 28.681 72.357 22.410 1.00 23.13 ? 1615 HOH A O 1 HETATM 9181 O O . HOH G 5 . ? 30.940 71.004 21.307 1.00 36.36 ? 1616 HOH A O 1 HETATM 9182 O O . HOH G 5 . ? 32.574 69.267 24.432 1.00 24.55 ? 1617 HOH A O 1 HETATM 9183 O O . HOH G 5 . ? 34.399 70.386 25.713 1.00 37.85 ? 1618 HOH A O 1 HETATM 9184 O O . HOH G 5 . ? 37.618 71.406 26.069 1.00 46.58 ? 1619 HOH A O 1 HETATM 9185 O O . HOH G 5 . ? 35.623 68.308 23.267 1.00 33.46 ? 1620 HOH A O 1 HETATM 9186 O O . HOH G 5 . ? 36.012 65.852 22.201 1.00 33.09 ? 1621 HOH A O 1 HETATM 9187 O O . HOH G 5 . ? 35.626 67.766 20.558 1.00 27.19 ? 1622 HOH A O 1 HETATM 9188 O O . HOH G 5 . ? 32.963 66.941 21.332 1.00 21.56 ? 1623 HOH A O 1 HETATM 9189 O O . HOH G 5 . ? 33.528 60.212 23.271 1.00 10.56 ? 1624 HOH A O 1 HETATM 9190 O O . HOH G 5 . ? 27.878 60.857 19.430 1.00 8.44 ? 1625 HOH A O 1 HETATM 9191 O O . HOH G 5 . ? 30.139 55.702 17.157 1.00 8.14 ? 1626 HOH A O 1 HETATM 9192 O O . HOH G 5 . ? 27.691 53.249 20.049 1.00 11.91 ? 1627 HOH A O 1 HETATM 9193 O O . HOH G 5 . ? 26.938 51.273 22.622 1.00 20.82 ? 1628 HOH A O 1 HETATM 9194 O O A HOH G 5 . ? 26.698 51.322 12.949 0.50 9.39 ? 1629 HOH A O 1 HETATM 9195 O O B HOH G 5 . ? 27.571 50.772 13.257 0.50 6.51 ? 1629 HOH A O 1 HETATM 9196 O O A HOH G 5 . ? 25.446 53.546 11.153 0.50 6.31 ? 1630 HOH A O 1 HETATM 9197 O O B HOH G 5 . ? 25.495 52.304 12.505 0.50 12.82 ? 1630 HOH A O 1 HETATM 9198 O O . HOH G 5 . ? 27.904 48.414 12.095 1.00 13.80 ? 1631 HOH A O 1 HETATM 9199 O O . HOH G 5 . ? 27.206 46.294 13.632 1.00 12.71 ? 1632 HOH A O 1 HETATM 9200 O O . HOH G 5 . ? 28.233 43.788 13.176 1.00 7.80 ? 1633 HOH A O 1 HETATM 9201 O O . HOH G 5 . ? 27.175 41.281 13.264 1.00 13.74 ? 1634 HOH A O 1 HETATM 9202 O O . HOH G 5 . ? 25.010 39.832 14.255 1.00 16.59 ? 1635 HOH A O 1 HETATM 9203 O O . HOH G 5 . ? 23.196 36.899 13.377 1.00 30.55 ? 1636 HOH A O 1 HETATM 9204 O O . HOH G 5 . ? 22.237 34.587 12.307 1.00 37.53 ? 1637 HOH A O 1 HETATM 9205 O O . HOH G 5 . ? 25.406 33.278 13.341 1.00 24.05 ? 1638 HOH A O 1 HETATM 9206 O O . HOH G 5 . ? 24.113 34.260 15.507 1.00 26.55 ? 1639 HOH A O 1 HETATM 9207 O O . HOH G 5 . ? 21.577 37.947 15.630 1.00 25.29 ? 1640 HOH A O 1 HETATM 9208 O O . HOH G 5 . ? 19.685 39.081 17.631 1.00 15.05 ? 1641 HOH A O 1 HETATM 9209 O O . HOH G 5 . ? 18.654 37.514 19.642 1.00 24.52 ? 1642 HOH A O 1 HETATM 9210 O O . HOH G 5 . ? 19.260 36.250 22.308 1.00 26.53 ? 1643 HOH A O 1 HETATM 9211 O O . HOH G 5 . ? 19.879 35.533 25.623 1.00 27.09 ? 1644 HOH A O 1 HETATM 9212 O O . HOH G 5 . ? 18.519 31.998 25.491 1.00 30.32 ? 1645 HOH A O 1 HETATM 9213 O O . HOH G 5 . ? 18.287 28.955 23.425 1.00 33.97 ? 1646 HOH A O 1 HETATM 9214 O O . HOH G 5 . ? 19.544 81.588 -42.661 1.00 35.31 ? 1647 HOH A O 1 HETATM 9215 O O . HOH G 5 . ? 22.064 80.644 -42.176 1.00 27.71 ? 1648 HOH A O 1 HETATM 9216 O O . HOH G 5 . ? 12.330 33.732 25.832 1.00 31.02 ? 1649 HOH A O 1 HETATM 9217 O O . HOH G 5 . ? 14.937 33.908 26.988 1.00 43.00 ? 1650 HOH A O 1 HETATM 9218 O O . HOH G 5 . ? 18.464 34.133 29.097 1.00 37.62 ? 1651 HOH A O 1 HETATM 9219 O O . HOH G 5 . ? 20.808 31.645 31.345 1.00 28.41 ? 1652 HOH A O 1 HETATM 9220 O O . HOH G 5 . ? 20.650 32.433 33.599 1.00 38.59 ? 1653 HOH A O 1 HETATM 9221 O O . HOH G 5 . ? 22.646 30.701 34.220 1.00 41.23 ? 1654 HOH A O 1 HETATM 9222 O O . HOH G 5 . ? 24.382 29.566 31.493 1.00 33.69 ? 1655 HOH A O 1 HETATM 9223 O O . HOH G 5 . ? 26.736 30.690 30.253 1.00 34.71 ? 1656 HOH A O 1 HETATM 9224 O O . HOH G 5 . ? 26.119 32.787 28.666 1.00 22.73 ? 1657 HOH A O 1 HETATM 9225 O O . HOH G 5 . ? 27.207 34.944 29.504 1.00 21.57 ? 1658 HOH A O 1 HETATM 9226 O O . HOH G 5 . ? 26.273 37.419 29.392 1.00 14.93 ? 1659 HOH A O 1 HETATM 9227 O O . HOH G 5 . ? 29.975 36.537 29.042 1.00 20.98 ? 1660 HOH A O 1 HETATM 9228 O O . HOH G 5 . ? 27.994 34.833 32.191 1.00 36.33 ? 1661 HOH A O 1 HETATM 9229 O O . HOH G 5 . ? 24.351 34.504 35.725 1.00 24.74 ? 1662 HOH A O 1 HETATM 9230 O O . HOH G 5 . ? 21.838 35.093 34.688 1.00 30.66 ? 1663 HOH A O 1 HETATM 9231 O O . HOH G 5 . ? 17.638 36.666 35.522 1.00 35.90 ? 1664 HOH A O 1 HETATM 9232 O O . HOH G 5 . ? 16.051 35.979 37.593 1.00 46.57 ? 1665 HOH A O 1 HETATM 9233 O O . HOH G 5 . ? 17.381 39.868 36.348 1.00 54.24 ? 1666 HOH A O 1 HETATM 9234 O O . HOH G 5 . ? 16.067 40.067 34.204 1.00 41.76 ? 1667 HOH A O 1 HETATM 9235 O O . HOH G 5 . ? 17.371 41.666 32.092 1.00 34.32 ? 1668 HOH A O 1 HETATM 9236 O O . HOH G 5 . ? 19.475 43.159 33.826 1.00 29.49 ? 1669 HOH A O 1 HETATM 9237 O O . HOH G 5 . ? 20.910 41.754 35.121 1.00 24.48 ? 1670 HOH A O 1 HETATM 9238 O O . HOH G 5 . ? 20.275 40.987 37.349 1.00 33.02 ? 1671 HOH A O 1 HETATM 9239 O O . HOH G 5 . ? 28.259 40.526 38.770 1.00 36.87 ? 1672 HOH A O 1 HETATM 9240 O O . HOH G 5 . ? 27.992 37.868 39.212 1.00 42.59 ? 1673 HOH A O 1 HETATM 9241 O O . HOH G 5 . ? 28.646 35.491 37.722 1.00 32.63 ? 1674 HOH A O 1 HETATM 9242 O O . HOH G 5 . ? 28.095 44.165 38.462 1.00 32.83 ? 1675 HOH A O 1 HETATM 9243 O O . HOH G 5 . ? 29.087 46.913 37.103 1.00 16.97 ? 1676 HOH A O 1 HETATM 9244 O O . HOH G 5 . ? 31.617 47.517 37.836 1.00 34.83 ? 1677 HOH A O 1 HETATM 9245 O O . HOH G 5 . ? 32.891 49.230 39.829 1.00 32.43 ? 1678 HOH A O 1 HETATM 9246 O O . HOH G 5 . ? 29.975 51.139 39.902 1.00 40.06 ? 1679 HOH A O 1 HETATM 9247 O O . HOH G 5 . ? 28.227 49.164 38.400 1.00 25.87 ? 1680 HOH A O 1 HETATM 9248 O O . HOH G 5 . ? 34.049 47.830 36.183 1.00 27.67 ? 1681 HOH A O 1 HETATM 9249 O O . HOH G 5 . ? 36.383 47.104 35.133 1.00 33.60 ? 1682 HOH A O 1 HETATM 9250 O O . HOH G 5 . ? 34.726 45.755 33.339 1.00 17.52 ? 1683 HOH A O 1 HETATM 9251 O O . HOH G 5 . ? 37.404 47.128 29.689 1.00 17.52 ? 1684 HOH A O 1 HETATM 9252 O O . HOH G 5 . ? 37.005 45.503 27.443 1.00 11.71 ? 1685 HOH A O 1 HETATM 9253 O O A HOH G 5 . ? 39.323 45.150 25.883 0.50 13.98 ? 1686 HOH A O 1 HETATM 9254 O O B HOH G 5 . ? 39.059 43.582 26.888 0.50 20.14 ? 1686 HOH A O 1 HETATM 9255 O O . HOH G 5 . ? 39.190 41.189 26.248 1.00 39.69 ? 1687 HOH A O 1 HETATM 9256 O O . HOH G 5 . ? 37.048 39.840 26.598 1.00 28.40 ? 1688 HOH A O 1 HETATM 9257 O O . HOH G 5 . ? 36.807 37.077 25.301 1.00 35.52 ? 1689 HOH A O 1 HETATM 9258 O O . HOH G 5 . ? 34.560 36.203 23.530 1.00 36.80 ? 1690 HOH A O 1 HETATM 9259 O O . HOH G 5 . ? 32.376 34.815 24.230 1.00 34.95 ? 1691 HOH A O 1 HETATM 9260 O O . HOH G 5 . ? 32.443 33.959 26.717 1.00 37.96 ? 1692 HOH A O 1 HETATM 9261 O O . HOH G 5 . ? 29.618 31.357 21.908 1.00 29.61 ? 1693 HOH A O 1 HETATM 9262 O O . HOH G 5 . ? 30.135 30.265 19.461 1.00 45.05 ? 1694 HOH A O 1 HETATM 9263 O O . HOH G 5 . ? 28.253 29.058 18.431 1.00 42.07 ? 1695 HOH A O 1 HETATM 9264 O O . HOH G 5 . ? 29.386 28.491 15.524 1.00 42.35 ? 1696 HOH A O 1 HETATM 9265 O O . HOH G 5 . ? 32.710 30.926 15.946 1.00 35.71 ? 1697 HOH A O 1 HETATM 9266 O O . HOH G 5 . ? 31.922 33.512 16.987 1.00 26.14 ? 1698 HOH A O 1 HETATM 9267 O O . HOH G 5 . ? 34.355 34.314 16.153 1.00 18.84 ? 1699 HOH A O 1 HETATM 9268 O O . HOH G 5 . ? 36.233 36.659 19.599 1.00 47.37 ? 1700 HOH A O 1 HETATM 9269 O O . HOH G 5 . ? 38.210 36.206 17.768 1.00 27.61 ? 1701 HOH A O 1 HETATM 9270 O O . HOH G 5 . ? 39.217 38.772 17.228 1.00 14.46 ? 1702 HOH A O 1 HETATM 9271 O O . HOH G 5 . ? 41.880 39.056 16.551 1.00 24.50 ? 1703 HOH A O 1 HETATM 9272 O O . HOH G 5 . ? 43.171 39.809 18.763 1.00 45.09 ? 1704 HOH A O 1 HETATM 9273 O O . HOH G 5 . ? 41.350 37.025 20.719 1.00 37.40 ? 1705 HOH A O 1 HETATM 9274 O O . HOH G 5 . ? 39.540 39.549 20.045 1.00 29.73 ? 1706 HOH A O 1 HETATM 9275 O O . HOH G 5 . ? 38.065 38.622 21.946 1.00 34.17 ? 1707 HOH A O 1 HETATM 9276 O O . HOH G 5 . ? 38.887 42.968 22.694 1.00 24.66 ? 1708 HOH A O 1 HETATM 9277 O O . HOH G 5 . ? 41.819 40.814 27.774 1.00 28.79 ? 1709 HOH A O 1 HETATM 9278 O O . HOH G 5 . ? 46.511 43.636 28.343 1.00 34.85 ? 1710 HOH A O 1 HETATM 9279 O O . HOH G 5 . ? 47.102 45.756 26.541 1.00 29.76 ? 1711 HOH A O 1 HETATM 9280 O O . HOH G 5 . ? 44.275 45.381 25.411 1.00 35.94 ? 1712 HOH A O 1 HETATM 9281 O O . HOH G 5 . ? 45.628 44.945 23.136 1.00 35.35 ? 1713 HOH A O 1 HETATM 9282 O O . HOH G 5 . ? 43.631 44.964 19.125 1.00 40.30 ? 1714 HOH A O 1 HETATM 9283 O O . HOH G 5 . ? 46.070 46.102 16.483 1.00 30.11 ? 1715 HOH A O 1 HETATM 9284 O O . HOH G 5 . ? 48.019 48.212 16.521 1.00 13.60 ? 1716 HOH A O 1 HETATM 9285 O O . HOH G 5 . ? 47.929 49.473 13.916 1.00 11.71 ? 1717 HOH A O 1 HETATM 9286 O O . HOH G 5 . ? 46.948 48.510 11.620 1.00 14.74 ? 1718 HOH A O 1 HETATM 9287 O O . HOH G 5 . ? 46.672 45.822 11.694 1.00 33.72 ? 1719 HOH A O 1 HETATM 9288 O O . HOH G 5 . ? 48.496 44.878 10.210 1.00 39.73 ? 1720 HOH A O 1 HETATM 9289 O O . HOH G 5 . ? 51.237 45.162 10.163 1.00 24.71 ? 1721 HOH A O 1 HETATM 9290 O O . HOH G 5 . ? 53.355 44.919 12.420 1.00 37.21 ? 1722 HOH A O 1 HETATM 9291 O O . HOH G 5 . ? 54.187 47.698 15.608 1.00 21.96 ? 1723 HOH A O 1 HETATM 9292 O O . HOH G 5 . ? 55.097 50.305 17.001 1.00 25.69 ? 1724 HOH A O 1 HETATM 9293 O O . HOH G 5 . ? 58.958 51.152 14.962 1.00 30.62 ? 1725 HOH A O 1 HETATM 9294 O O . HOH G 5 . ? 60.083 51.168 12.722 1.00 35.97 ? 1726 HOH A O 1 HETATM 9295 O O . HOH G 5 . ? 61.790 51.647 9.620 1.00 40.42 ? 1727 HOH A O 1 HETATM 9296 O O . HOH G 5 . ? 60.061 51.368 6.083 1.00 39.17 ? 1728 HOH A O 1 HETATM 9297 O O . HOH G 5 . ? 58.374 52.832 4.794 1.00 28.38 ? 1729 HOH A O 1 HETATM 9298 O O . HOH G 5 . ? 59.359 52.074 2.716 1.00 26.02 ? 1730 HOH A O 1 HETATM 9299 O O . HOH G 5 . ? 58.715 52.641 -0.062 1.00 11.51 ? 1731 HOH A O 1 HETATM 9300 O O . HOH G 5 . ? 59.221 50.064 -0.494 1.00 15.61 ? 1732 HOH A O 1 HETATM 9301 O O . HOH G 5 . ? 59.678 49.073 2.186 1.00 29.61 ? 1733 HOH A O 1 HETATM 9302 O O . HOH G 5 . ? 60.383 45.955 0.936 1.00 33.46 ? 1734 HOH A O 1 HETATM 9303 O O . HOH G 5 . ? 58.944 46.319 -1.514 1.00 20.87 ? 1735 HOH A O 1 HETATM 9304 O O . HOH G 5 . ? 60.907 45.265 -3.714 1.00 34.82 ? 1736 HOH A O 1 HETATM 9305 O O . HOH G 5 . ? 62.698 44.643 -0.364 1.00 27.87 ? 1737 HOH A O 1 HETATM 9306 O O . HOH G 5 . ? 64.269 43.390 -2.305 1.00 28.06 ? 1738 HOH A O 1 HETATM 9307 O O . HOH G 5 . ? 65.665 45.661 -3.029 1.00 28.88 ? 1739 HOH A O 1 HETATM 9308 O O . HOH G 5 . ? 67.310 46.647 -1.045 1.00 24.74 ? 1740 HOH A O 1 HETATM 9309 O O . HOH G 5 . ? 67.994 49.405 -0.793 1.00 24.06 ? 1741 HOH A O 1 HETATM 9310 O O . HOH G 5 . ? 65.860 50.523 0.558 1.00 47.44 ? 1742 HOH A O 1 HETATM 9311 O O . HOH G 5 . ? 67.180 52.793 1.628 1.00 36.88 ? 1743 HOH A O 1 HETATM 9312 O O . HOH G 5 . ? 67.048 55.354 1.064 1.00 20.22 ? 1744 HOH A O 1 HETATM 9313 O O . HOH G 5 . ? 63.700 57.243 0.932 1.00 26.21 ? 1745 HOH A O 1 HETATM 9314 O O . HOH G 5 . ? 63.141 58.673 -1.331 1.00 14.70 ? 1746 HOH A O 1 HETATM 9315 O O . HOH G 5 . ? 64.825 59.301 -3.436 1.00 14.21 ? 1747 HOH A O 1 HETATM 9316 O O . HOH G 5 . ? 63.045 61.186 -4.713 1.00 15.96 ? 1748 HOH A O 1 HETATM 9317 O O . HOH G 5 . ? 63.061 61.300 -7.437 1.00 8.79 ? 1749 HOH A O 1 HETATM 9318 O O . HOH G 5 . ? 65.567 60.349 -7.573 1.00 8.55 ? 1750 HOH A O 1 HETATM 9319 O O . HOH G 5 . ? 67.415 60.721 -5.525 1.00 11.51 ? 1751 HOH A O 1 HETATM 9320 O O . HOH G 5 . ? 68.675 58.291 -4.913 1.00 12.97 ? 1752 HOH A O 1 HETATM 9321 O O . HOH G 5 . ? 69.099 61.471 -2.257 1.00 15.16 ? 1753 HOH A O 1 HETATM 9322 O O . HOH G 5 . ? 70.384 62.054 0.225 1.00 27.64 ? 1754 HOH A O 1 HETATM 9323 O O . HOH G 5 . ? 71.289 59.784 1.248 1.00 27.92 ? 1755 HOH A O 1 HETATM 9324 O O . HOH G 5 . ? 73.202 58.243 4.645 1.00 39.35 ? 1756 HOH A O 1 HETATM 9325 O O . HOH G 5 . ? 73.356 62.894 -0.762 1.00 37.64 ? 1757 HOH A O 1 HETATM 9326 O O . HOH G 5 . ? 71.906 66.897 2.180 1.00 34.50 ? 1758 HOH A O 1 HETATM 9327 O O . HOH G 5 . ? 69.310 65.420 2.902 1.00 42.35 ? 1759 HOH A O 1 HETATM 9328 O O . HOH G 5 . ? 67.870 67.002 1.210 1.00 35.28 ? 1760 HOH A O 1 HETATM 9329 O O A HOH G 5 . ? 65.818 65.954 -0.409 0.50 9.33 ? 1761 HOH A O 1 HETATM 9330 O O B HOH G 5 . ? 65.492 66.880 0.352 0.50 13.04 ? 1761 HOH A O 1 HETATM 9331 O O . HOH G 5 . ? 67.805 65.542 -3.272 1.00 14.27 ? 1762 HOH A O 1 HETATM 9332 O O . HOH G 5 . ? 66.167 68.678 2.252 1.00 29.92 ? 1763 HOH A O 1 HETATM 9333 O O . HOH G 5 . ? 62.647 64.104 2.782 1.00 32.05 ? 1764 HOH A O 1 HETATM 9334 O O . HOH G 5 . ? 61.995 63.668 4.981 1.00 36.34 ? 1765 HOH A O 1 HETATM 9335 O O . HOH G 5 . ? 59.591 64.223 7.047 1.00 37.29 ? 1766 HOH A O 1 HETATM 9336 O O . HOH G 5 . ? 57.831 62.826 8.587 1.00 20.51 ? 1767 HOH A O 1 HETATM 9337 O O . HOH G 5 . ? 58.823 60.569 5.667 1.00 27.88 ? 1768 HOH A O 1 HETATM 9338 O O . HOH G 5 . ? 57.420 58.404 5.444 1.00 22.24 ? 1769 HOH A O 1 HETATM 9339 O O . HOH G 5 . ? 55.175 59.077 3.955 1.00 13.28 ? 1770 HOH A O 1 HETATM 9340 O O . HOH G 5 . ? 56.207 58.478 1.417 1.00 32.15 ? 1771 HOH A O 1 HETATM 9341 O O . HOH G 5 . ? 54.935 57.626 -0.424 1.00 15.75 ? 1772 HOH A O 1 HETATM 9342 O O . HOH G 5 . ? 56.315 55.703 -2.045 1.00 10.01 ? 1773 HOH A O 1 HETATM 9343 O O . HOH G 5 . ? 56.113 53.418 -0.534 1.00 6.57 ? 1774 HOH A O 1 HETATM 9344 O O . HOH G 5 . ? 58.835 56.776 -1.301 1.00 11.55 ? 1775 HOH A O 1 HETATM 9345 O O . HOH G 5 . ? 60.661 58.276 -2.749 1.00 11.82 ? 1776 HOH A O 1 HETATM 9346 O O . HOH G 5 . ? 60.592 60.874 -3.449 1.00 13.19 ? 1777 HOH A O 1 HETATM 9347 O O . HOH G 5 . ? 60.409 62.200 -1.170 1.00 12.48 ? 1778 HOH A O 1 HETATM 9348 O O . HOH G 5 . ? 62.104 60.691 0.549 1.00 22.74 ? 1779 HOH A O 1 HETATM 9349 O O . HOH G 5 . ? 58.815 58.216 1.086 1.00 25.83 ? 1780 HOH A O 1 HETATM 9350 O O . HOH G 5 . ? 60.659 56.161 2.206 1.00 30.92 ? 1781 HOH A O 1 HETATM 9351 O O . HOH G 5 . ? 59.606 55.336 4.563 1.00 44.30 ? 1782 HOH A O 1 HETATM 9352 O O . HOH G 5 . ? 60.499 54.823 -0.196 1.00 12.09 ? 1783 HOH A O 1 HETATM 9353 O O . HOH G 5 . ? 63.367 52.019 -0.308 1.00 27.50 ? 1784 HOH A O 1 HETATM 9354 O O . HOH G 5 . ? 70.877 49.538 0.175 1.00 19.94 ? 1785 HOH A O 1 HETATM 9355 O O . HOH G 5 . ? 71.916 47.022 -0.089 1.00 34.36 ? 1786 HOH A O 1 HETATM 9356 O O . HOH G 5 . ? 72.671 51.290 2.046 1.00 30.24 ? 1787 HOH A O 1 HETATM 9357 O O . HOH G 5 . ? 76.753 51.200 1.771 1.00 42.74 ? 1788 HOH A O 1 HETATM 9358 O O . HOH G 5 . ? 75.821 48.412 -5.433 1.00 40.22 ? 1789 HOH A O 1 HETATM 9359 O O . HOH G 5 . ? 73.933 46.861 -4.599 1.00 40.24 ? 1790 HOH A O 1 HETATM 9360 O O . HOH G 5 . ? 79.130 47.007 -5.033 1.00 36.10 ? 1791 HOH A O 1 HETATM 9361 O O . HOH G 5 . ? 10.368 50.408 -8.976 1.00 40.76 ? 1792 HOH A O 1 HETATM 9362 O O . HOH G 5 . ? 10.399 47.574 -10.658 1.00 41.58 ? 1793 HOH A O 1 HETATM 9363 O O . HOH G 5 . ? 73.398 51.629 -11.174 1.00 29.62 ? 1794 HOH A O 1 HETATM 9364 O O . HOH G 5 . ? 70.583 52.249 -12.305 1.00 22.40 ? 1795 HOH A O 1 HETATM 9365 O O . HOH G 5 . ? 71.156 54.474 -13.661 1.00 32.79 ? 1796 HOH A O 1 HETATM 9366 O O . HOH G 5 . ? 69.997 56.385 -12.336 1.00 28.05 ? 1797 HOH A O 1 HETATM 9367 O O . HOH G 5 . ? 71.948 58.686 -11.193 1.00 27.78 ? 1798 HOH A O 1 HETATM 9368 O O . HOH G 5 . ? 74.296 60.213 -9.414 1.00 30.24 ? 1799 HOH A O 1 HETATM 9369 O O . HOH G 5 . ? 74.304 62.683 -8.289 1.00 42.22 ? 1800 HOH A O 1 HETATM 9370 O O . HOH G 5 . ? 72.917 65.062 -7.707 1.00 17.39 ? 1801 HOH A O 1 HETATM 9371 O O . HOH G 5 . ? 72.932 66.633 -9.901 1.00 20.74 ? 1802 HOH A O 1 HETATM 9372 O O . HOH G 5 . ? 75.616 67.061 -9.401 1.00 29.55 ? 1803 HOH A O 1 HETATM 9373 O O . HOH G 5 . ? 77.440 66.244 -11.753 1.00 28.35 ? 1804 HOH A O 1 HETATM 9374 O O . HOH G 5 . ? 78.519 68.579 -12.193 1.00 21.25 ? 1805 HOH A O 1 HETATM 9375 O O . HOH G 5 . ? 79.200 67.453 -14.830 1.00 26.45 ? 1806 HOH A O 1 HETATM 9376 O O . HOH G 5 . ? 77.501 65.018 -14.793 1.00 26.19 ? 1807 HOH A O 1 HETATM 9377 O O . HOH G 5 . ? 75.142 64.225 -16.169 1.00 27.99 ? 1808 HOH A O 1 HETATM 9378 O O . HOH G 5 . ? 74.352 63.588 -13.989 1.00 28.03 ? 1809 HOH A O 1 HETATM 9379 O O . HOH G 5 . ? 74.598 61.103 -13.246 1.00 38.89 ? 1810 HOH A O 1 HETATM 9380 O O . HOH G 5 . ? 71.463 62.591 -17.834 1.00 26.21 ? 1811 HOH A O 1 HETATM 9381 O O . HOH G 5 . ? 70.259 61.990 -20.185 1.00 22.49 ? 1812 HOH A O 1 HETATM 9382 O O . HOH G 5 . ? 70.270 59.453 -20.760 1.00 34.23 ? 1813 HOH A O 1 HETATM 9383 O O . HOH G 5 . ? 70.030 60.441 -23.259 1.00 28.32 ? 1814 HOH A O 1 HETATM 9384 O O . HOH G 5 . ? 69.799 63.014 -23.689 1.00 25.69 ? 1815 HOH A O 1 HETATM 9385 O O . HOH G 5 . ? 72.578 63.885 -21.026 1.00 27.83 ? 1816 HOH A O 1 HETATM 9386 O O . HOH G 5 . ? 73.791 65.991 -17.522 1.00 15.02 ? 1817 HOH A O 1 HETATM 9387 O O . HOH G 5 . ? 80.569 63.425 -16.870 1.00 26.69 ? 1818 HOH A O 1 HETATM 9388 O O . HOH G 5 . ? 80.202 64.126 -21.447 1.00 22.53 ? 1819 HOH A O 1 HETATM 9389 O O . HOH G 5 . ? 79.237 63.318 -23.865 1.00 33.98 ? 1820 HOH A O 1 HETATM 9390 O O A HOH G 5 . ? 80.923 61.186 -24.067 0.50 15.99 ? 1821 HOH A O 1 HETATM 9391 O O B HOH G 5 . ? 12.880 62.147 -24.785 0.50 17.76 ? 1821 HOH A O 1 HETATM 9392 O O . HOH G 5 . ? 78.145 64.636 -26.279 1.00 30.79 ? 1822 HOH A O 1 HETATM 9393 O O . HOH G 5 . ? 83.563 66.012 -24.871 1.00 33.75 ? 1823 HOH A O 1 HETATM 9394 O O . HOH G 5 . ? 84.026 68.479 -27.462 1.00 32.52 ? 1824 HOH A O 1 HETATM 9395 O O . HOH G 5 . ? 82.219 69.501 -25.193 1.00 47.32 ? 1825 HOH A O 1 HETATM 9396 O O . HOH G 5 . ? 83.373 70.269 -22.944 1.00 29.87 ? 1826 HOH A O 1 HETATM 9397 O O . HOH G 5 . ? 83.416 70.068 -20.066 1.00 33.12 ? 1827 HOH A O 1 HETATM 9398 O O . HOH G 5 . ? 84.150 68.122 -17.179 1.00 15.47 ? 1828 HOH A O 1 HETATM 9399 O O . HOH G 5 . ? 79.749 73.660 -17.629 1.00 25.27 ? 1829 HOH A O 1 HETATM 9400 O O . HOH G 5 . ? 77.587 74.932 -18.125 1.00 35.44 ? 1830 HOH A O 1 HETATM 9401 O O . HOH G 5 . ? 75.331 74.064 -19.147 1.00 22.93 ? 1831 HOH A O 1 HETATM 9402 O O . HOH G 5 . ? 73.153 76.677 -18.428 1.00 34.29 ? 1832 HOH A O 1 HETATM 9403 O O . HOH G 5 . ? 74.595 77.475 -20.602 1.00 35.14 ? 1833 HOH A O 1 HETATM 9404 O O . HOH G 5 . ? 71.590 78.834 -17.583 1.00 38.87 ? 1834 HOH A O 1 HETATM 9405 O O . HOH G 5 . ? 68.346 78.981 -18.034 1.00 26.20 ? 1835 HOH A O 1 HETATM 9406 O O . HOH G 5 . ? 71.092 83.910 -14.743 1.00 38.46 ? 1836 HOH A O 1 HETATM 9407 O O . HOH G 5 . ? 71.604 84.592 -19.951 1.00 32.56 ? 1837 HOH A O 1 HETATM 9408 O O . HOH G 5 . ? 73.106 82.434 -21.092 1.00 27.15 ? 1838 HOH A O 1 HETATM 9409 O O . HOH G 5 . ? 75.106 83.802 -22.873 1.00 35.57 ? 1839 HOH A O 1 HETATM 9410 O O . HOH G 5 . ? 79.060 79.992 -25.687 1.00 50.74 ? 1840 HOH A O 1 HETATM 9411 O O . HOH G 5 . ? 76.957 80.723 -28.283 1.00 34.51 ? 1841 HOH A O 1 HETATM 9412 O O . HOH G 5 . ? 11.885 76.331 -25.940 1.00 43.91 ? 1842 HOH A O 1 HETATM 9413 O O . HOH G 5 . ? 12.703 77.790 -23.459 1.00 44.50 ? 1843 HOH A O 1 HETATM 9414 O O . HOH G 5 . ? 12.874 74.331 -23.286 1.00 36.14 ? 1844 HOH A O 1 HETATM 9415 O O . HOH G 5 . ? 76.568 74.107 -26.475 1.00 30.54 ? 1845 HOH A O 1 HETATM 9416 O O . HOH G 5 . ? 72.336 63.325 -27.621 1.00 40.67 ? 1846 HOH A O 1 HETATM 9417 O O . HOH G 5 . ? 69.847 63.880 -28.075 1.00 34.39 ? 1847 HOH A O 1 HETATM 9418 O O A HOH G 5 . ? 66.563 66.875 -32.450 0.50 19.12 ? 1848 HOH A O 1 HETATM 9419 O O B HOH G 5 . ? 67.325 65.908 -32.888 0.50 20.08 ? 1848 HOH A O 1 HETATM 9420 O O . HOH G 5 . ? 63.214 67.928 -31.641 1.00 21.39 ? 1849 HOH A O 1 HETATM 9421 O O . HOH G 5 . ? 63.845 65.768 -30.163 1.00 32.84 ? 1850 HOH A O 1 HETATM 9422 O O . HOH G 5 . ? 61.778 63.889 -30.660 1.00 23.82 ? 1851 HOH A O 1 HETATM 9423 O O . HOH G 5 . ? 67.280 64.551 -38.483 1.00 16.77 ? 1852 HOH A O 1 HETATM 9424 O O . HOH G 5 . ? 67.972 66.039 -40.611 1.00 11.40 ? 1853 HOH A O 1 HETATM 9425 O O . HOH G 5 . ? 58.286 77.229 -38.494 1.00 13.51 ? 1854 HOH A O 1 HETATM 9426 O O . HOH G 5 . ? 51.249 76.185 -40.857 1.00 23.66 ? 1855 HOH A O 1 HETATM 9427 O O . HOH G 5 . ? 54.555 82.663 -44.346 1.00 40.25 ? 1856 HOH A O 1 HETATM 9428 O O . HOH G 5 . ? 53.830 90.840 -42.938 1.00 31.68 ? 1857 HOH A O 1 HETATM 9429 O O . HOH G 5 . ? 53.528 92.643 -40.861 1.00 31.97 ? 1858 HOH A O 1 HETATM 9430 O O . HOH G 5 . ? 56.283 93.865 -41.075 1.00 39.45 ? 1859 HOH A O 1 HETATM 9431 O O . HOH G 5 . ? 61.249 90.879 -37.189 1.00 31.53 ? 1860 HOH A O 1 HETATM 9432 O O . HOH G 5 . ? 59.321 91.123 -35.334 1.00 23.38 ? 1861 HOH A O 1 HETATM 9433 O O . HOH G 5 . ? 61.466 92.204 -33.858 1.00 33.94 ? 1862 HOH A O 1 HETATM 9434 O O . HOH G 5 . ? 63.864 92.274 -34.171 1.00 24.83 ? 1863 HOH A O 1 HETATM 9435 O O . HOH G 5 . ? 63.855 90.844 -36.360 1.00 33.61 ? 1864 HOH A O 1 HETATM 9436 O O . HOH G 5 . ? 65.416 89.279 -37.246 1.00 34.37 ? 1865 HOH A O 1 HETATM 9437 O O . HOH G 5 . ? 67.798 88.072 -35.150 1.00 28.68 ? 1866 HOH A O 1 HETATM 9438 O O . HOH G 5 . ? 67.179 85.587 -36.089 1.00 32.66 ? 1867 HOH A O 1 HETATM 9439 O O . HOH G 5 . ? 71.418 85.679 -35.457 1.00 45.02 ? 1868 HOH A O 1 HETATM 9440 O O . HOH G 5 . ? 65.360 87.365 -41.402 1.00 36.14 ? 1869 HOH A O 1 HETATM 9441 O O . HOH G 5 . ? 64.254 93.569 -39.168 1.00 39.28 ? 1870 HOH A O 1 HETATM 9442 O O . HOH G 5 . ? 64.459 94.332 -35.802 1.00 32.00 ? 1871 HOH A O 1 HETATM 9443 O O . HOH G 5 . ? 66.505 96.012 -35.404 1.00 38.96 ? 1872 HOH A O 1 HETATM 9444 O O . HOH G 5 . ? 68.411 98.156 -34.120 1.00 48.47 ? 1873 HOH A O 1 HETATM 9445 O O . HOH G 5 . ? 69.427 98.766 -36.542 1.00 38.07 ? 1874 HOH A O 1 HETATM 9446 O O . HOH G 5 . ? 70.246 95.407 -35.031 1.00 40.36 ? 1875 HOH A O 1 HETATM 9447 O O . HOH G 5 . ? 72.089 95.679 -31.348 1.00 28.85 ? 1876 HOH A O 1 HETATM 9448 O O . HOH G 5 . ? 60.277 91.100 -31.251 1.00 25.55 ? 1877 HOH A O 1 HETATM 9449 O O . HOH G 5 . ? 56.281 92.815 -29.798 1.00 25.49 ? 1878 HOH A O 1 HETATM 9450 O O . HOH G 5 . ? 58.380 92.803 -26.807 1.00 25.12 ? 1879 HOH A O 1 HETATM 9451 O O . HOH G 5 . ? 56.147 90.952 -25.837 1.00 24.40 ? 1880 HOH A O 1 HETATM 9452 O O . HOH G 5 . ? 54.831 90.303 -23.571 1.00 35.14 ? 1881 HOH A O 1 HETATM 9453 O O . HOH G 5 . ? 56.383 90.043 -21.330 1.00 42.37 ? 1882 HOH A O 1 HETATM 9454 O O . HOH G 5 . ? 56.990 87.423 -20.002 1.00 38.35 ? 1883 HOH A O 1 HETATM 9455 O O . HOH G 5 . ? 53.322 87.285 -21.091 1.00 28.33 ? 1884 HOH A O 1 HETATM 9456 O O . HOH G 5 . ? 51.472 87.398 -17.332 1.00 42.72 ? 1885 HOH A O 1 HETATM 9457 O O . HOH G 5 . ? 49.388 86.074 -11.439 1.00 43.77 ? 1886 HOH A O 1 HETATM 9458 O O . HOH G 5 . ? 44.794 83.876 -11.234 1.00 38.38 ? 1887 HOH A O 1 HETATM 9459 O O . HOH G 5 . ? 43.105 82.171 -10.400 1.00 27.16 ? 1888 HOH A O 1 HETATM 9460 O O . HOH G 5 . ? 43.703 83.081 -8.017 1.00 40.20 ? 1889 HOH A O 1 HETATM 9461 O O . HOH G 5 . ? 45.465 79.106 -7.631 1.00 26.49 ? 1890 HOH A O 1 HETATM 9462 O O . HOH G 5 . ? 48.295 78.016 -9.783 1.00 28.18 ? 1891 HOH A O 1 HETATM 9463 O O . HOH G 5 . ? 49.607 79.676 -11.250 1.00 37.35 ? 1892 HOH A O 1 HETATM 9464 O O . HOH G 5 . ? 41.250 77.500 -14.081 1.00 11.14 ? 1893 HOH A O 1 HETATM 9465 O O . HOH G 5 . ? 42.120 75.177 -16.037 1.00 13.17 ? 1894 HOH A O 1 HETATM 9466 O O A HOH G 5 . ? 45.071 69.021 -17.190 0.50 10.99 ? 1895 HOH A O 1 HETATM 9467 O O B HOH G 5 . ? 45.652 69.868 -18.564 0.50 17.52 ? 1895 HOH A O 1 HETATM 9468 O O . HOH G 5 . ? 46.338 67.590 -15.551 1.00 16.80 ? 1896 HOH A O 1 HETATM 9469 O O . HOH G 5 . ? 48.814 69.333 -15.382 1.00 32.33 ? 1897 HOH A O 1 HETATM 9470 O O . HOH G 5 . ? 49.363 70.766 -17.519 1.00 33.47 ? 1898 HOH A O 1 HETATM 9471 O O . HOH G 5 . ? 51.515 69.917 -18.595 1.00 28.38 ? 1899 HOH A O 1 HETATM 9472 O O . HOH G 5 . ? 51.172 71.434 -20.350 1.00 24.29 ? 1900 HOH A O 1 HETATM 9473 O O . HOH G 5 . ? 53.462 72.592 -19.200 1.00 13.12 ? 1901 HOH A O 1 HETATM 9474 O O . HOH G 5 . ? 49.778 73.711 -21.806 1.00 31.26 ? 1902 HOH A O 1 HETATM 9475 O O . HOH G 5 . ? 47.420 71.944 -20.132 1.00 26.42 ? 1903 HOH A O 1 HETATM 9476 O O . HOH G 5 . ? 50.859 70.830 -23.495 1.00 17.84 ? 1904 HOH A O 1 HETATM 9477 O O . HOH G 5 . ? 45.304 71.937 -25.827 1.00 39.28 ? 1905 HOH A O 1 HETATM 9478 O O . HOH G 5 . ? 47.147 70.481 -28.395 1.00 37.08 ? 1906 HOH A O 1 HETATM 9479 O O . HOH G 5 . ? 47.311 68.209 -30.516 1.00 20.47 ? 1907 HOH A O 1 HETATM 9480 O O . HOH G 5 . ? 48.088 74.233 -28.880 1.00 33.04 ? 1908 HOH A O 1 HETATM 9481 O O . HOH G 5 . ? 43.417 68.236 -25.045 1.00 18.25 ? 1909 HOH A O 1 HETATM 9482 O O . HOH G 5 . ? 39.233 62.750 -19.118 1.00 6.34 ? 1910 HOH A O 1 HETATM 9483 O O . HOH G 5 . ? 39.206 64.741 -14.693 1.00 10.09 ? 1911 HOH A O 1 HETATM 9484 O O . HOH G 5 . ? 42.012 63.422 -7.189 1.00 6.09 ? 1912 HOH A O 1 HETATM 9485 O O A HOH G 5 . ? 49.509 62.152 -8.715 0.50 12.63 ? 1913 HOH A O 1 HETATM 9486 O O B HOH G 5 . ? 48.878 60.992 -7.996 0.50 12.63 ? 1913 HOH A O 1 HETATM 9487 O O A HOH G 5 . ? 50.023 59.459 -11.477 0.50 14.74 ? 1914 HOH A O 1 HETATM 9488 O O B HOH G 5 . ? 49.411 61.110 -10.462 0.50 14.74 ? 1914 HOH A O 1 HETATM 9489 O O A HOH G 5 . ? 50.817 59.825 -8.832 0.50 18.04 ? 1915 HOH A O 1 HETATM 9490 O O B HOH G 5 . ? 50.959 58.718 -9.920 0.50 18.04 ? 1915 HOH A O 1 HETATM 9491 O O . HOH G 5 . ? 49.797 57.503 -7.526 1.00 11.61 ? 1916 HOH A O 1 HETATM 9492 O O . HOH G 5 . ? 51.426 56.556 -5.576 1.00 8.33 ? 1917 HOH A O 1 HETATM 9493 O O . HOH G 5 . ? 52.169 54.040 -4.800 1.00 7.60 ? 1918 HOH A O 1 HETATM 9494 O O . HOH G 5 . ? 52.665 58.801 -1.736 1.00 13.74 ? 1919 HOH A O 1 HETATM 9495 O O . HOH G 5 . ? 56.929 60.969 1.628 1.00 15.82 ? 1920 HOH A O 1 HETATM 9496 O O . HOH G 5 . ? 55.979 66.851 5.449 1.00 29.01 ? 1921 HOH A O 1 HETATM 9497 O O . HOH G 5 . ? 55.127 68.348 3.614 1.00 28.32 ? 1922 HOH A O 1 HETATM 9498 O O . HOH G 5 . ? 53.474 69.325 2.350 1.00 30.76 ? 1923 HOH A O 1 HETATM 9499 O O . HOH G 5 . ? 51.119 68.813 3.379 1.00 27.42 ? 1924 HOH A O 1 HETATM 9500 O O . HOH G 5 . ? 49.751 67.233 4.416 1.00 17.33 ? 1925 HOH A O 1 HETATM 9501 O O . HOH G 5 . ? 49.392 68.288 6.766 1.00 27.10 ? 1926 HOH A O 1 HETATM 9502 O O . HOH G 5 . ? 51.095 66.319 8.335 1.00 21.96 ? 1927 HOH A O 1 HETATM 9503 O O A HOH G 5 . ? 52.874 67.784 9.089 0.50 21.49 ? 1928 HOH A O 1 HETATM 9504 O O B HOH G 5 . ? 54.002 66.312 8.645 0.50 35.88 ? 1928 HOH A O 1 HETATM 9505 O O . HOH G 5 . ? 55.685 67.186 10.455 1.00 34.10 ? 1929 HOH A O 1 HETATM 9506 O O . HOH G 5 . ? 55.388 67.469 13.526 1.00 29.77 ? 1930 HOH A O 1 HETATM 9507 O O . HOH G 5 . ? 57.151 69.157 13.675 1.00 33.84 ? 1931 HOH A O 1 HETATM 9508 O O . HOH G 5 . ? 54.221 73.342 16.145 1.00 36.00 ? 1932 HOH A O 1 HETATM 9509 O O . HOH G 5 . ? 53.350 75.905 15.920 1.00 39.85 ? 1933 HOH A O 1 HETATM 9510 O O . HOH G 5 . ? 50.739 76.323 14.468 1.00 21.51 ? 1934 HOH A O 1 HETATM 9511 O O . HOH G 5 . ? 51.568 77.433 11.919 1.00 38.27 ? 1935 HOH A O 1 HETATM 9512 O O . HOH G 5 . ? 51.603 74.497 8.626 1.00 41.72 ? 1936 HOH A O 1 HETATM 9513 O O A HOH G 5 . ? 50.254 72.210 9.196 0.50 12.08 ? 1937 HOH A O 1 HETATM 9514 O O B HOH G 5 . ? 50.678 71.372 7.988 0.50 17.94 ? 1937 HOH A O 1 HETATM 9515 O O A HOH G 5 . ? 52.449 70.735 8.797 0.50 19.32 ? 1938 HOH A O 1 HETATM 9516 O O B HOH G 5 . ? 51.510 69.207 9.254 0.50 22.92 ? 1938 HOH A O 1 HETATM 9517 O O . HOH G 5 . ? 52.273 70.933 5.840 1.00 38.41 ? 1939 HOH A O 1 HETATM 9518 O O . HOH G 5 . ? 52.564 73.019 4.004 1.00 28.56 ? 1940 HOH A O 1 HETATM 9519 O O . HOH G 5 . ? 52.610 75.037 1.785 1.00 30.76 ? 1941 HOH A O 1 HETATM 9520 O O . HOH G 5 . ? 54.947 75.507 2.421 1.00 36.60 ? 1942 HOH A O 1 HETATM 9521 O O . HOH G 5 . ? 56.459 76.096 0.352 1.00 33.92 ? 1943 HOH A O 1 HETATM 9522 O O . HOH G 5 . ? 61.821 76.280 1.670 1.00 38.91 ? 1944 HOH A O 1 HETATM 9523 O O . HOH G 5 . ? 63.985 77.072 0.215 1.00 34.18 ? 1945 HOH A O 1 HETATM 9524 O O . HOH G 5 . ? 59.540 71.252 0.234 1.00 33.09 ? 1946 HOH A O 1 HETATM 9525 O O . HOH G 5 . ? 58.739 70.359 3.233 1.00 37.31 ? 1947 HOH A O 1 HETATM 9526 O O . HOH G 5 . ? 59.186 68.164 2.574 1.00 20.44 ? 1948 HOH A O 1 HETATM 9527 O O . HOH G 5 . ? 64.024 70.611 -5.185 1.00 14.20 ? 1949 HOH A O 1 HETATM 9528 O O . HOH G 5 . ? 64.665 70.573 -7.825 1.00 36.09 ? 1950 HOH A O 1 HETATM 9529 O O . HOH G 5 . ? 66.462 71.507 -6.717 1.00 19.83 ? 1951 HOH A O 1 HETATM 9530 O O . HOH G 5 . ? 70.000 69.961 -12.491 1.00 11.53 ? 1952 HOH A O 1 HETATM 9531 O O . HOH G 5 . ? 74.652 76.086 -14.441 1.00 24.70 ? 1953 HOH A O 1 HETATM 9532 O O . HOH G 5 . ? 77.154 76.171 -11.844 1.00 34.32 ? 1954 HOH A O 1 HETATM 9533 O O . HOH G 5 . ? 78.001 72.050 -10.190 1.00 30.16 ? 1955 HOH A O 1 HETATM 9534 O O . HOH G 5 . ? 73.879 80.201 -10.879 1.00 40.96 ? 1956 HOH A O 1 HETATM 9535 O O . HOH G 5 . ? 59.736 83.613 -14.148 1.00 44.38 ? 1957 HOH A O 1 HETATM 9536 O O . HOH G 5 . ? 59.697 83.671 -16.725 1.00 36.90 ? 1958 HOH A O 1 HETATM 9537 O O . HOH G 5 . ? 54.786 80.974 -23.678 1.00 14.41 ? 1959 HOH A O 1 HETATM 9538 O O . HOH G 5 . ? 52.477 91.914 -23.482 1.00 36.21 ? 1960 HOH A O 1 HETATM 9539 O O . HOH G 5 . ? 54.163 93.312 -24.881 1.00 35.71 ? 1961 HOH A O 1 HETATM 9540 O O . HOH G 5 . ? 51.018 95.902 -26.483 1.00 28.42 ? 1962 HOH A O 1 HETATM 9541 O O . HOH G 5 . ? 48.402 95.326 -27.164 1.00 19.36 ? 1963 HOH A O 1 HETATM 9542 O O . HOH G 5 . ? 45.211 94.990 -26.560 1.00 34.09 ? 1964 HOH A O 1 HETATM 9543 O O . HOH G 5 . ? 45.067 92.530 -25.538 1.00 39.59 ? 1965 HOH A O 1 HETATM 9544 O O . HOH G 5 . ? 43.405 93.369 -23.974 1.00 38.03 ? 1966 HOH A O 1 HETATM 9545 O O . HOH G 5 . ? 45.043 89.977 -25.545 1.00 16.94 ? 1967 HOH A O 1 HETATM 9546 O O . HOH G 5 . ? 46.855 89.144 -23.310 1.00 44.42 ? 1968 HOH A O 1 HETATM 9547 O O . HOH G 5 . ? 49.387 91.951 -24.784 1.00 32.03 ? 1969 HOH A O 1 HETATM 9548 O O . HOH G 5 . ? 48.180 89.218 -30.919 1.00 12.13 ? 1970 HOH A O 1 HETATM 9549 O O . HOH G 5 . ? 44.442 95.631 -30.497 1.00 26.69 ? 1971 HOH A O 1 HETATM 9550 O O . HOH G 5 . ? 42.304 94.528 -30.229 1.00 41.22 ? 1972 HOH A O 1 HETATM 9551 O O . HOH G 5 . ? 37.238 96.582 -30.793 1.00 40.73 ? 1973 HOH A O 1 HETATM 9552 O O . HOH G 5 . ? 34.965 94.765 -32.309 1.00 23.89 ? 1974 HOH A O 1 HETATM 9553 O O . HOH G 5 . ? 33.711 93.424 -30.313 1.00 41.32 ? 1975 HOH A O 1 HETATM 9554 O O . HOH G 5 . ? 36.063 93.483 -29.776 1.00 31.65 ? 1976 HOH A O 1 HETATM 9555 O O . HOH G 5 . ? 31.802 96.485 -27.398 1.00 40.34 ? 1977 HOH A O 1 HETATM 9556 O O . HOH G 5 . ? 27.821 97.656 -28.551 1.00 45.89 ? 1978 HOH A O 1 HETATM 9557 O O . HOH G 5 . ? 26.754 99.153 -26.373 1.00 36.59 ? 1979 HOH A O 1 HETATM 9558 O O . HOH G 5 . ? 25.124 97.526 -31.754 1.00 44.38 ? 1980 HOH A O 1 HETATM 9559 O O . HOH G 5 . ? 27.794 93.481 -29.815 1.00 38.80 ? 1981 HOH A O 1 HETATM 9560 O O . HOH G 5 . ? 26.805 91.609 -27.619 1.00 26.31 ? 1982 HOH A O 1 HETATM 9561 O O . HOH G 5 . ? 24.630 92.927 -28.122 1.00 37.42 ? 1983 HOH A O 1 HETATM 9562 O O . HOH G 5 . ? 23.981 90.917 -26.040 1.00 35.68 ? 1984 HOH A O 1 HETATM 9563 O O . HOH G 5 . ? 25.122 88.558 -25.422 1.00 29.44 ? 1985 HOH A O 1 HETATM 9564 O O . HOH G 5 . ? 26.797 87.719 -23.765 1.00 21.49 ? 1986 HOH A O 1 HETATM 9565 O O . HOH G 5 . ? 28.033 90.772 -25.310 1.00 17.31 ? 1987 HOH A O 1 HETATM 9566 O O . HOH G 5 . ? 29.509 88.661 -26.196 1.00 10.17 ? 1988 HOH A O 1 HETATM 9567 O O . HOH G 5 . ? 27.040 89.824 -31.702 1.00 38.07 ? 1989 HOH A O 1 HETATM 9568 O O . HOH G 5 . ? 25.555 91.438 -32.781 1.00 29.91 ? 1990 HOH A O 1 HETATM 9569 O O . HOH G 5 . ? 23.258 86.877 -32.578 1.00 26.39 ? 1991 HOH A O 1 HETATM 9570 O O . HOH G 5 . ? 25.605 85.993 -31.905 1.00 14.93 ? 1992 HOH A O 1 HETATM 9571 O O . HOH G 5 . ? 21.409 85.865 -30.897 1.00 31.29 ? 1993 HOH A O 1 HETATM 9572 O O . HOH G 5 . ? 19.071 83.262 -25.766 1.00 26.97 ? 1994 HOH A O 1 HETATM 9573 O O . HOH G 5 . ? 16.818 85.227 -24.075 1.00 39.64 ? 1995 HOH A O 1 HETATM 9574 O O . HOH G 5 . ? 13.928 88.096 -20.007 1.00 30.11 ? 1996 HOH A O 1 HETATM 9575 O O . HOH G 5 . ? 14.669 83.499 -18.866 1.00 41.36 ? 1997 HOH A O 1 HETATM 9576 O O . HOH G 5 . ? 17.353 81.041 -16.862 1.00 35.00 ? 1998 HOH A O 1 HETATM 9577 O O . HOH G 5 . ? 19.517 84.152 -18.346 1.00 28.53 ? 1999 HOH A O 1 HETATM 9578 O O . HOH G 5 . ? 21.584 86.176 -19.102 1.00 25.82 ? 2000 HOH A O 1 HETATM 9579 O O . HOH G 5 . ? 22.752 88.456 -18.774 1.00 33.76 ? 2001 HOH A O 1 HETATM 9580 O O . HOH G 5 . ? 23.166 85.356 -16.866 1.00 31.40 ? 2002 HOH A O 1 HETATM 9581 O O . HOH G 5 . ? 24.827 83.057 -16.907 1.00 22.89 ? 2003 HOH A O 1 HETATM 9582 O O . HOH G 5 . ? 25.323 87.382 -15.994 1.00 42.72 ? 2004 HOH A O 1 HETATM 9583 O O . HOH G 5 . ? 27.487 86.294 -14.993 1.00 32.59 ? 2005 HOH A O 1 HETATM 9584 O O . HOH G 5 . ? 28.901 86.647 -13.301 1.00 34.41 ? 2006 HOH A O 1 HETATM 9585 O O . HOH G 5 . ? 30.269 87.084 -15.084 1.00 22.74 ? 2007 HOH A O 1 HETATM 9586 O O . HOH G 5 . ? 29.691 87.203 -17.859 1.00 23.35 ? 2008 HOH A O 1 HETATM 9587 O O . HOH G 5 . ? 31.547 85.740 -19.775 1.00 20.46 ? 2009 HOH A O 1 HETATM 9588 O O . HOH G 5 . ? 32.754 87.947 -18.937 1.00 53.84 ? 2010 HOH A O 1 HETATM 9589 O O . HOH G 5 . ? 35.118 87.791 -19.744 1.00 33.32 ? 2011 HOH A O 1 HETATM 9590 O O . HOH G 5 . ? 35.309 86.057 -17.922 1.00 27.70 ? 2012 HOH A O 1 HETATM 9591 O O . HOH G 5 . ? 33.393 84.244 -18.291 1.00 17.34 ? 2013 HOH A O 1 HETATM 9592 O O . HOH G 5 . ? 37.254 86.273 -15.948 1.00 35.64 ? 2014 HOH A O 1 HETATM 9593 O O . HOH G 5 . ? 40.627 85.282 -12.702 1.00 35.32 ? 2015 HOH A O 1 HETATM 9594 O O . HOH G 5 . ? 40.443 82.733 -10.962 1.00 18.09 ? 2016 HOH A O 1 HETATM 9595 O O . HOH G 5 . ? 35.587 85.881 -8.278 1.00 35.91 ? 2017 HOH A O 1 HETATM 9596 O O . HOH G 5 . ? 33.956 86.895 -10.446 1.00 31.46 ? 2018 HOH A O 1 HETATM 9597 O O . HOH G 5 . ? 27.482 88.666 -12.298 1.00 32.79 ? 2019 HOH A O 1 HETATM 9598 O O . HOH G 5 . ? 21.314 85.985 -10.574 1.00 34.81 ? 2020 HOH A O 1 HETATM 9599 O O . HOH G 5 . ? 21.121 83.692 -12.482 1.00 31.01 ? 2021 HOH A O 1 HETATM 9600 O O . HOH G 5 . ? 18.860 80.583 -11.676 1.00 29.28 ? 2022 HOH A O 1 HETATM 9601 O O . HOH G 5 . ? 13.643 80.377 -5.970 1.00 32.37 ? 2023 HOH A O 1 HETATM 9602 O O . HOH G 5 . ? 16.866 74.401 -3.039 1.00 11.22 ? 2024 HOH A O 1 HETATM 9603 O O . HOH G 5 . ? 20.092 74.187 -6.861 1.00 10.65 ? 2025 HOH A O 1 HETATM 9604 O O . HOH G 5 . ? 24.633 70.444 -8.758 1.00 12.11 ? 2026 HOH A O 1 HETATM 9605 O O . HOH G 5 . ? 26.790 68.784 -9.248 1.00 7.88 ? 2027 HOH A O 1 HETATM 9606 O O . HOH G 5 . ? 32.571 64.706 -9.875 1.00 18.02 ? 2028 HOH A O 1 HETATM 9607 O O . HOH G 5 . ? 34.294 58.515 -8.811 1.00 7.52 ? 2029 HOH A O 1 HETATM 9608 O O . HOH G 5 . ? 30.279 58.329 -11.817 1.00 6.22 ? 2030 HOH A O 1 HETATM 9609 O O . HOH G 5 . ? 23.256 54.237 -8.585 1.00 27.79 ? 2031 HOH A O 1 HETATM 9610 O O . HOH G 5 . ? 23.083 51.702 -8.573 1.00 13.06 ? 2032 HOH A O 1 HETATM 9611 O O . HOH G 5 . ? 25.657 51.098 -9.492 1.00 11.28 ? 2033 HOH A O 1 HETATM 9612 O O . HOH G 5 . ? 24.243 53.065 -6.346 1.00 15.46 ? 2034 HOH A O 1 HETATM 9613 O O . HOH G 5 . ? 23.365 53.813 -3.729 1.00 11.88 ? 2035 HOH A O 1 HETATM 9614 O O . HOH G 5 . ? 24.335 55.444 -1.819 1.00 12.08 ? 2036 HOH A O 1 HETATM 9615 O O . HOH G 5 . ? 20.669 57.223 -5.287 1.00 7.97 ? 2037 HOH A O 1 HETATM 9616 O O . HOH G 5 . ? 21.549 57.812 -7.817 1.00 7.38 ? 2038 HOH A O 1 HETATM 9617 O O . HOH G 5 . ? 19.880 57.330 -11.798 1.00 12.97 ? 2039 HOH A O 1 HETATM 9618 O O . HOH G 5 . ? 20.376 58.630 -21.948 1.00 8.89 ? 2040 HOH A O 1 HETATM 9619 O O . HOH G 5 . ? 23.851 55.390 -23.440 1.00 7.22 ? 2041 HOH A O 1 HETATM 9620 O O . HOH G 5 . ? 22.964 52.933 -24.427 1.00 10.08 ? 2042 HOH A O 1 HETATM 9621 O O . HOH G 5 . ? 20.254 52.531 -24.305 1.00 12.88 ? 2043 HOH A O 1 HETATM 9622 O O . HOH G 5 . ? 19.069 50.303 -23.506 1.00 32.30 ? 2044 HOH A O 1 HETATM 9623 O O . HOH G 5 . ? 21.639 48.734 -22.536 1.00 31.94 ? 2045 HOH A O 1 HETATM 9624 O O . HOH G 5 . ? 23.993 48.310 -24.072 1.00 29.57 ? 2046 HOH A O 1 HETATM 9625 O O . HOH G 5 . ? 24.823 50.912 -24.070 1.00 11.63 ? 2047 HOH A O 1 HETATM 9626 O O . HOH G 5 . ? 26.959 47.516 -23.880 1.00 30.59 ? 2048 HOH A O 1 HETATM 9627 O O . HOH G 5 . ? 27.723 48.382 -21.802 1.00 13.19 ? 2049 HOH A O 1 HETATM 9628 O O . HOH G 5 . ? 25.402 46.796 -20.900 1.00 23.92 ? 2050 HOH A O 1 HETATM 9629 O O . HOH G 5 . ? 28.827 49.608 -24.338 1.00 14.09 ? 2051 HOH A O 1 HETATM 9630 O O . HOH G 5 . ? 31.393 49.836 -24.072 1.00 10.27 ? 2052 HOH A O 1 HETATM 9631 O O . HOH G 5 . ? 34.164 56.223 -26.275 1.00 9.13 ? 2053 HOH A O 1 HETATM 9632 O O . HOH G 5 . ? 32.223 58.497 -28.473 1.00 10.65 ? 2054 HOH A O 1 HETATM 9633 O O . HOH G 5 . ? 31.924 51.062 -35.474 1.00 19.59 ? 2055 HOH A O 1 HETATM 9634 O O . HOH G 5 . ? 35.004 48.741 -37.985 1.00 43.96 ? 2056 HOH A O 1 HETATM 9635 O O . HOH G 5 . ? 38.328 46.292 -39.952 1.00 40.71 ? 2057 HOH A O 1 HETATM 9636 O O . HOH G 5 . ? 26.600 46.281 -37.343 1.00 42.42 ? 2058 HOH A O 1 HETATM 9637 O O . HOH G 5 . ? 28.212 47.028 -31.601 1.00 24.93 ? 2059 HOH A O 1 HETATM 9638 O O . HOH G 5 . ? 28.677 43.932 -29.768 1.00 31.28 ? 2060 HOH A O 1 HETATM 9639 O O . HOH G 5 . ? 29.428 42.050 -28.271 1.00 33.17 ? 2061 HOH A O 1 HETATM 9640 O O . HOH G 5 . ? 29.529 41.033 -25.608 1.00 22.41 ? 2062 HOH A O 1 HETATM 9641 O O . HOH G 5 . ? 28.742 38.771 -24.736 1.00 37.90 ? 2063 HOH A O 1 HETATM 9642 O O . HOH G 5 . ? 27.688 38.680 -22.585 1.00 29.14 ? 2064 HOH A O 1 HETATM 9643 O O . HOH G 5 . ? 28.610 41.205 -21.686 1.00 13.05 ? 2065 HOH A O 1 HETATM 9644 O O . HOH G 5 . ? 27.488 36.511 -19.799 1.00 24.14 ? 2066 HOH A O 1 HETATM 9645 O O . HOH G 5 . ? 25.504 35.638 -18.085 1.00 30.36 ? 2067 HOH A O 1 HETATM 9646 O O . HOH G 5 . ? 25.302 36.362 -15.310 1.00 31.57 ? 2068 HOH A O 1 HETATM 9647 O O . HOH G 5 . ? 22.934 38.825 -15.845 1.00 45.03 ? 2069 HOH A O 1 HETATM 9648 O O . HOH G 5 . ? 20.147 37.042 -16.961 1.00 46.67 ? 2070 HOH A O 1 HETATM 9649 O O . HOH G 5 . ? 23.970 38.953 -21.116 1.00 36.27 ? 2071 HOH A O 1 HETATM 9650 O O . HOH G 5 . ? 29.365 34.913 -16.398 1.00 24.43 ? 2072 HOH A O 1 HETATM 9651 O O . HOH G 5 . ? 30.391 35.066 -12.410 1.00 19.67 ? 2073 HOH A O 1 HETATM 9652 O O . HOH G 5 . ? 30.528 34.738 -9.763 1.00 27.99 ? 2074 HOH A O 1 HETATM 9653 O O . HOH G 5 . ? 33.273 32.300 -9.546 1.00 40.46 ? 2075 HOH A O 1 HETATM 9654 O O . HOH G 5 . ? 30.432 33.423 -6.229 1.00 31.21 ? 2076 HOH A O 1 HETATM 9655 O O . HOH G 5 . ? 28.265 35.234 -6.813 1.00 17.39 ? 2077 HOH A O 1 HETATM 9656 O O . HOH G 5 . ? 25.407 34.383 -7.466 1.00 29.67 ? 2078 HOH A O 1 HETATM 9657 O O . HOH G 5 . ? 21.443 35.362 -5.387 1.00 33.97 ? 2079 HOH A O 1 HETATM 9658 O O . HOH G 5 . ? 21.481 36.724 -7.934 1.00 39.29 ? 2080 HOH A O 1 HETATM 9659 O O . HOH G 5 . ? 25.961 33.494 -2.783 1.00 35.17 ? 2081 HOH A O 1 HETATM 9660 O O . HOH G 5 . ? 21.102 34.964 5.629 1.00 43.47 ? 2082 HOH A O 1 HETATM 9661 O O . HOH G 5 . ? 18.459 36.716 5.714 1.00 26.45 ? 2083 HOH A O 1 HETATM 9662 O O . HOH G 5 . ? 16.190 37.865 6.058 1.00 37.00 ? 2084 HOH A O 1 HETATM 9663 O O . HOH G 5 . ? 14.925 40.580 8.775 1.00 40.13 ? 2085 HOH A O 1 HETATM 9664 O O . HOH G 5 . ? 17.279 41.419 9.278 1.00 24.30 ? 2086 HOH A O 1 HETATM 9665 O O . HOH G 5 . ? 14.408 40.144 12.393 1.00 37.15 ? 2087 HOH A O 1 HETATM 9666 O O . HOH G 5 . ? 12.886 42.345 12.482 1.00 16.48 ? 2088 HOH A O 1 HETATM 9667 O O . HOH G 5 . ? 10.052 41.960 11.927 1.00 32.12 ? 2089 HOH A O 1 HETATM 9668 O O . HOH G 5 . ? 8.574 44.543 12.952 1.00 30.48 ? 2090 HOH A O 1 HETATM 9669 O O . HOH G 5 . ? 8.037 47.843 11.702 1.00 23.16 ? 2091 HOH A O 1 HETATM 9670 O O . HOH G 5 . ? 7.634 50.628 12.450 1.00 35.75 ? 2092 HOH A O 1 HETATM 9671 O O . HOH G 5 . ? 6.371 52.276 15.430 1.00 40.43 ? 2093 HOH A O 1 HETATM 9672 O O . HOH G 5 . ? 7.396 54.177 17.092 1.00 33.55 ? 2094 HOH A O 1 HETATM 9673 O O . HOH G 5 . ? 8.658 56.482 16.541 1.00 41.01 ? 2095 HOH A O 1 HETATM 9674 O O . HOH G 5 . ? 9.352 58.750 17.483 1.00 34.64 ? 2096 HOH A O 1 HETATM 9675 O O . HOH G 5 . ? 34.312 67.491 12.278 1.00 12.96 ? 2097 HOH A O 1 HETATM 9676 O O . HOH G 5 . ? 36.215 65.608 12.212 1.00 33.62 ? 2098 HOH A O 1 HETATM 9677 O O . HOH G 5 . ? 34.580 70.237 12.985 1.00 13.76 ? 2099 HOH A O 1 HETATM 9678 O O . HOH G 5 . ? 35.156 73.293 18.687 1.00 41.85 ? 2100 HOH A O 1 HETATM 9679 O O . HOH G 5 . ? 37.981 73.613 18.123 1.00 30.50 ? 2101 HOH A O 1 HETATM 9680 O O . HOH G 5 . ? 38.116 77.066 17.690 1.00 42.69 ? 2102 HOH A O 1 HETATM 9681 O O . HOH G 5 . ? 39.400 77.934 19.649 1.00 38.21 ? 2103 HOH A O 1 HETATM 9682 O O . HOH G 5 . ? 42.178 73.950 22.768 1.00 42.34 ? 2104 HOH A O 1 HETATM 9683 O O . HOH G 5 . ? 45.321 74.089 22.668 1.00 31.75 ? 2105 HOH A O 1 HETATM 9684 O O . HOH G 5 . ? 49.152 74.419 23.011 1.00 42.88 ? 2106 HOH A O 1 HETATM 9685 O O . HOH G 5 . ? 48.686 72.576 24.853 1.00 44.35 ? 2107 HOH A O 1 HETATM 9686 O O . HOH G 5 . ? 50.024 68.366 23.640 1.00 45.07 ? 2108 HOH A O 1 HETATM 9687 O O . HOH G 5 . ? 52.462 67.472 22.788 1.00 48.07 ? 2109 HOH A O 1 HETATM 9688 O O . HOH G 5 . ? 53.258 66.153 20.162 1.00 39.19 ? 2110 HOH A O 1 HETATM 9689 O O . HOH G 5 . ? 52.745 69.503 18.323 1.00 21.83 ? 2111 HOH A O 1 HETATM 9690 O O . HOH G 5 . ? 52.449 72.474 18.149 1.00 25.51 ? 2112 HOH A O 1 HETATM 9691 O O . HOH G 5 . ? 57.726 69.250 20.104 1.00 36.91 ? 2113 HOH A O 1 HETATM 9692 O O . HOH G 5 . ? 57.204 67.277 22.808 1.00 32.52 ? 2114 HOH A O 1 HETATM 9693 O O . HOH G 5 . ? 56.827 64.727 24.279 1.00 26.95 ? 2115 HOH A O 1 HETATM 9694 O O . HOH G 5 . ? 59.175 62.318 25.697 1.00 30.18 ? 2116 HOH A O 1 HETATM 9695 O O . HOH G 5 . ? 58.176 61.899 28.001 1.00 40.12 ? 2117 HOH A O 1 HETATM 9696 O O . HOH G 5 . ? 62.224 62.421 25.481 1.00 31.21 ? 2118 HOH A O 1 HETATM 9697 O O . HOH G 5 . ? 63.212 57.280 25.875 1.00 34.23 ? 2119 HOH A O 1 HETATM 9698 O O . HOH G 5 . ? 61.710 55.897 27.722 1.00 35.80 ? 2120 HOH A O 1 HETATM 9699 O O . HOH G 5 . ? 59.066 55.617 27.148 1.00 25.86 ? 2121 HOH A O 1 HETATM 9700 O O . HOH G 5 . ? 57.907 52.906 26.316 1.00 28.05 ? 2122 HOH A O 1 HETATM 9701 O O . HOH G 5 . ? 55.584 52.135 27.342 1.00 31.09 ? 2123 HOH A O 1 HETATM 9702 O O . HOH G 5 . ? 53.170 52.689 26.373 1.00 28.12 ? 2124 HOH A O 1 HETATM 9703 O O . HOH G 5 . ? 52.050 49.800 26.476 1.00 37.05 ? 2125 HOH A O 1 HETATM 9704 O O . HOH G 5 . ? 48.996 49.749 28.297 1.00 17.99 ? 2126 HOH A O 1 HETATM 9705 O O . HOH G 5 . ? 49.711 47.300 29.096 1.00 25.92 ? 2127 HOH A O 1 HETATM 9706 O O . HOH G 5 . ? 49.179 50.587 32.667 1.00 30.36 ? 2128 HOH A O 1 HETATM 9707 O O . HOH G 5 . ? 46.858 53.218 35.723 1.00 43.55 ? 2129 HOH A O 1 HETATM 9708 O O . HOH G 5 . ? 42.508 53.145 35.512 1.00 19.37 ? 2130 HOH A O 1 HETATM 9709 O O . HOH G 5 . ? 40.004 52.810 36.323 1.00 29.04 ? 2131 HOH A O 1 HETATM 9710 O O . HOH G 5 . ? 39.193 49.881 36.435 1.00 37.34 ? 2132 HOH A O 1 HETATM 9711 O O . HOH G 5 . ? 41.196 50.340 33.186 1.00 23.50 ? 2133 HOH A O 1 HETATM 9712 O O . HOH G 5 . ? 41.863 48.765 31.235 1.00 19.62 ? 2134 HOH A O 1 HETATM 9713 O O . HOH G 5 . ? 39.194 49.275 30.098 1.00 23.34 ? 2135 HOH A O 1 HETATM 9714 O O . HOH G 5 . ? 42.308 46.197 32.806 1.00 38.44 ? 2136 HOH A O 1 HETATM 9715 O O . HOH G 5 . ? 34.260 51.110 35.959 1.00 36.04 ? 2137 HOH A O 1 HETATM 9716 O O . HOH G 5 . ? 31.492 57.302 37.432 1.00 25.46 ? 2138 HOH A O 1 HETATM 9717 O O . HOH G 5 . ? 30.097 57.542 39.817 1.00 33.49 ? 2139 HOH A O 1 HETATM 9718 O O . HOH G 5 . ? 29.788 59.418 34.828 1.00 27.94 ? 2140 HOH A O 1 HETATM 9719 O O . HOH G 5 . ? 33.996 59.762 35.004 1.00 34.82 ? 2141 HOH A O 1 HETATM 9720 O O . HOH G 5 . ? 35.667 58.678 36.756 1.00 40.53 ? 2142 HOH A O 1 HETATM 9721 O O . HOH G 5 . ? 38.380 58.372 36.773 1.00 39.15 ? 2143 HOH A O 1 HETATM 9722 O O . HOH G 5 . ? 41.689 58.433 34.537 1.00 26.67 ? 2144 HOH A O 1 HETATM 9723 O O . HOH G 5 . ? 43.371 56.626 33.615 1.00 27.13 ? 2145 HOH A O 1 HETATM 9724 O O . HOH G 5 . ? 45.349 58.053 32.470 1.00 33.05 ? 2146 HOH A O 1 HETATM 9725 O O . HOH G 5 . ? 41.810 61.545 33.519 1.00 38.89 ? 2147 HOH A O 1 HETATM 9726 O O . HOH G 5 . ? 37.400 62.129 35.574 1.00 29.25 ? 2148 HOH A O 1 HETATM 9727 O O . HOH G 5 . ? 35.208 62.310 34.092 1.00 24.32 ? 2149 HOH A O 1 HETATM 9728 O O . HOH G 5 . ? 38.497 66.448 36.751 1.00 42.81 ? 2150 HOH A O 1 HETATM 9729 O O . HOH G 5 . ? 38.764 68.512 35.357 1.00 36.19 ? 2151 HOH A O 1 HETATM 9730 O O . HOH G 5 . ? 40.699 66.774 34.148 1.00 35.71 ? 2152 HOH A O 1 HETATM 9731 O O . HOH G 5 . ? 39.703 67.022 31.300 1.00 20.02 ? 2153 HOH A O 1 HETATM 9732 O O . HOH G 5 . ? 41.772 67.440 29.259 1.00 22.20 ? 2154 HOH A O 1 HETATM 9733 O O . HOH G 5 . ? 44.401 67.797 28.123 1.00 36.69 ? 2155 HOH A O 1 HETATM 9734 O O . HOH G 5 . ? 46.394 68.537 26.465 1.00 25.71 ? 2156 HOH A O 1 HETATM 9735 O O . HOH G 5 . ? 47.604 66.012 26.896 1.00 26.91 ? 2157 HOH A O 1 HETATM 9736 O O . HOH G 5 . ? 50.608 61.901 26.508 1.00 17.42 ? 2158 HOH A O 1 HETATM 9737 O O . HOH G 5 . ? 51.861 60.165 28.110 1.00 28.94 ? 2159 HOH A O 1 HETATM 9738 O O . HOH G 5 . ? 51.824 63.737 24.660 1.00 29.11 ? 2160 HOH A O 1 HETATM 9739 O O . HOH G 5 . ? 42.104 69.070 26.339 1.00 39.84 ? 2161 HOH A O 1 HETATM 9740 O O . HOH G 5 . ? 42.723 71.613 25.828 1.00 50.70 ? 2162 HOH A O 1 HETATM 9741 O O . HOH G 5 . ? 45.294 77.785 16.200 1.00 38.44 ? 2163 HOH A O 1 HETATM 9742 O O . HOH G 5 . ? 46.848 77.206 14.257 1.00 34.63 ? 2164 HOH A O 1 HETATM 9743 O O . HOH G 5 . ? 46.913 78.383 12.028 1.00 28.12 ? 2165 HOH A O 1 HETATM 9744 O O . HOH G 5 . ? 45.865 77.674 9.537 1.00 19.32 ? 2166 HOH A O 1 HETATM 9745 O O . HOH G 5 . ? 48.112 76.493 8.195 1.00 29.51 ? 2167 HOH A O 1 HETATM 9746 O O . HOH G 5 . ? 46.515 74.447 7.840 1.00 10.99 ? 2168 HOH A O 1 HETATM 9747 O O . HOH G 5 . ? 43.386 73.120 5.875 1.00 9.68 ? 2169 HOH A O 1 HETATM 9748 O O . HOH G 5 . ? 49.166 76.343 5.512 1.00 28.13 ? 2170 HOH A O 1 HETATM 9749 O O . HOH G 5 . ? 48.514 77.721 3.492 1.00 39.90 ? 2171 HOH A O 1 HETATM 9750 O O . HOH G 5 . ? 50.570 77.164 2.115 1.00 29.55 ? 2172 HOH A O 1 HETATM 9751 O O . HOH G 5 . ? 51.350 80.094 0.845 1.00 33.99 ? 2173 HOH A O 1 HETATM 9752 O O . HOH G 5 . ? 51.185 79.286 -1.687 1.00 20.50 ? 2174 HOH A O 1 HETATM 9753 O O . HOH G 5 . ? 44.681 80.716 -1.440 1.00 31.78 ? 2175 HOH A O 1 HETATM 9754 O O . HOH G 5 . ? 45.919 79.535 5.147 1.00 25.53 ? 2176 HOH A O 1 HETATM 9755 O O . HOH G 5 . ? 43.214 80.537 5.442 1.00 20.47 ? 2177 HOH A O 1 HETATM 9756 O O . HOH G 5 . ? 40.893 81.490 11.333 1.00 37.74 ? 2178 HOH A O 1 HETATM 9757 O O . HOH G 5 . ? 38.553 80.124 12.788 1.00 48.72 ? 2179 HOH A O 1 HETATM 9758 O O . HOH G 5 . ? 31.250 81.415 0.532 1.00 16.93 ? 2180 HOH A O 1 HETATM 9759 O O . HOH G 5 . ? 30.269 85.624 1.596 1.00 25.81 ? 2181 HOH A O 1 HETATM 9760 O O . HOH G 5 . ? 24.644 85.408 7.834 1.00 30.89 ? 2182 HOH A O 1 HETATM 9761 O O . HOH G 5 . ? 21.676 79.781 5.275 1.00 24.63 ? 2183 HOH A O 1 HETATM 9762 O O A HOH G 5 . ? 26.515 74.605 2.326 0.50 8.74 ? 2184 HOH A O 1 HETATM 9763 O O B HOH G 5 . ? 26.162 75.700 1.547 0.50 11.32 ? 2184 HOH A O 1 HETATM 9764 O O . HOH G 5 . ? 26.063 72.580 5.606 1.00 10.80 ? 2185 HOH A O 1 HETATM 9765 O O . HOH G 5 . ? 20.631 67.908 8.341 1.00 16.69 ? 2186 HOH A O 1 HETATM 9766 O O . HOH G 5 . ? 20.752 65.171 7.712 1.00 14.31 ? 2187 HOH A O 1 HETATM 9767 O O . HOH G 5 . ? 13.106 62.543 11.649 1.00 28.44 ? 2188 HOH A O 1 HETATM 9768 O O . HOH G 5 . ? 10.152 61.888 9.987 1.00 38.52 ? 2189 HOH A O 1 HETATM 9769 O O . HOH G 5 . ? 4.548 59.039 10.935 1.00 42.71 ? 2190 HOH A O 1 HETATM 9770 O O . HOH G 5 . ? 11.358 52.963 6.762 1.00 15.50 ? 2191 HOH A O 1 HETATM 9771 O O . HOH G 5 . ? 10.995 53.368 3.892 1.00 35.25 ? 2192 HOH A O 1 HETATM 9772 O O . HOH G 5 . ? 10.589 51.551 2.282 1.00 41.00 ? 2193 HOH A O 1 HETATM 9773 O O . HOH G 5 . ? 10.712 51.235 -0.422 1.00 29.87 ? 2194 HOH A O 1 HETATM 9774 O O . HOH G 5 . ? 13.205 51.235 -2.055 1.00 28.17 ? 2195 HOH A O 1 HETATM 9775 O O . HOH G 5 . ? 14.469 50.380 0.833 1.00 28.25 ? 2196 HOH A O 1 HETATM 9776 O O . HOH G 5 . ? 13.386 48.094 1.498 1.00 27.62 ? 2197 HOH A O 1 HETATM 9777 O O . HOH G 5 . ? 12.002 47.737 -2.584 1.00 30.06 ? 2198 HOH A O 1 HETATM 9778 O O . HOH G 5 . ? 12.940 44.361 -2.612 1.00 40.51 ? 2199 HOH A O 1 HETATM 9779 O O . HOH G 5 . ? 16.626 42.947 -2.281 1.00 30.59 ? 2200 HOH A O 1 HETATM 9780 O O . HOH G 5 . ? 19.128 42.803 -2.323 1.00 26.90 ? 2201 HOH A O 1 HETATM 9781 O O . HOH G 5 . ? 14.960 40.479 -2.775 1.00 40.26 ? 2202 HOH A O 1 HETATM 9782 O O . HOH G 5 . ? 24.040 41.848 6.944 1.00 8.65 ? 2203 HOH A O 1 HETATM 9783 O O . HOH G 5 . ? 26.242 39.972 7.933 1.00 8.95 ? 2204 HOH A O 1 HETATM 9784 O O . HOH G 5 . ? 25.887 39.611 5.223 1.00 9.05 ? 2205 HOH A O 1 HETATM 9785 O O . HOH G 5 . ? 28.152 39.541 11.245 1.00 11.75 ? 2206 HOH A O 1 HETATM 9786 O O . HOH G 5 . ? 24.532 33.011 9.557 1.00 26.37 ? 2207 HOH A O 1 HETATM 9787 O O . HOH G 5 . ? 20.601 37.779 12.169 1.00 22.09 ? 2208 HOH A O 1 HETATM 9788 O O . HOH G 5 . ? 17.839 35.283 13.301 1.00 37.21 ? 2209 HOH A O 1 HETATM 9789 O O . HOH G 5 . ? 16.261 33.500 15.760 1.00 30.38 ? 2210 HOH A O 1 HETATM 9790 O O . HOH G 5 . ? 16.211 36.382 16.189 1.00 27.29 ? 2211 HOH A O 1 HETATM 9791 O O . HOH G 5 . ? 16.131 31.095 18.021 1.00 44.27 ? 2212 HOH A O 1 HETATM 9792 O O . HOH G 5 . ? 20.831 30.311 17.620 1.00 29.33 ? 2213 HOH A O 1 HETATM 9793 O O . HOH G 5 . ? 21.566 29.170 28.105 1.00 35.09 ? 2214 HOH A O 1 HETATM 9794 O O . HOH G 5 . ? 21.866 27.135 29.750 1.00 40.58 ? 2215 HOH A O 1 HETATM 9795 O O . HOH G 5 . ? 25.679 26.449 30.662 1.00 33.03 ? 2216 HOH A O 1 HETATM 9796 O O . HOH G 5 . ? 22.547 31.269 29.558 1.00 27.49 ? 2217 HOH A O 1 HETATM 9797 O O . HOH G 5 . ? 18.164 38.909 29.081 1.00 35.18 ? 2218 HOH A O 1 HETATM 9798 O O . HOH G 5 . ? 19.075 39.654 26.502 1.00 30.98 ? 2219 HOH A O 1 HETATM 9799 O O . HOH G 5 . ? 17.996 41.656 25.193 1.00 27.95 ? 2220 HOH A O 1 HETATM 9800 O O . HOH G 5 . ? 17.874 43.119 27.292 1.00 23.33 ? 2221 HOH A O 1 HETATM 9801 O O . HOH G 5 . ? 14.133 44.100 26.916 1.00 38.35 ? 2222 HOH A O 1 HETATM 9802 O O . HOH G 5 . ? 12.815 44.245 22.695 1.00 35.39 ? 2223 HOH A O 1 HETATM 9803 O O . HOH G 5 . ? 11.289 46.477 21.455 1.00 32.74 ? 2224 HOH A O 1 HETATM 9804 O O . HOH G 5 . ? 12.185 43.505 19.881 1.00 32.86 ? 2225 HOH A O 1 HETATM 9805 O O . HOH G 5 . ? 11.790 41.278 19.741 1.00 28.02 ? 2226 HOH A O 1 HETATM 9806 O O . HOH G 5 . ? 8.927 39.815 18.994 1.00 39.77 ? 2227 HOH A O 1 HETATM 9807 O O . HOH G 5 . ? 11.653 46.772 17.804 1.00 19.33 ? 2228 HOH A O 1 HETATM 9808 O O . HOH G 5 . ? 12.513 49.329 17.774 1.00 16.78 ? 2229 HOH A O 1 HETATM 9809 O O . HOH G 5 . ? 14.279 49.699 19.816 1.00 13.33 ? 2230 HOH A O 1 HETATM 9810 O O . HOH G 5 . ? 13.415 51.375 21.646 1.00 14.99 ? 2231 HOH A O 1 HETATM 9811 O O . HOH G 5 . ? 10.707 51.475 21.401 1.00 21.56 ? 2232 HOH A O 1 HETATM 9812 O O . HOH G 5 . ? 9.547 53.714 21.782 1.00 34.10 ? 2233 HOH A O 1 HETATM 9813 O O . HOH G 5 . ? 8.288 55.209 20.049 1.00 41.81 ? 2234 HOH A O 1 HETATM 9814 O O . HOH G 5 . ? 12.009 55.314 22.076 1.00 26.42 ? 2235 HOH A O 1 HETATM 9815 O O . HOH G 5 . ? 10.396 55.923 26.289 1.00 39.75 ? 2236 HOH A O 1 HETATM 9816 O O . HOH G 5 . ? 12.902 60.823 30.339 1.00 29.81 ? 2237 HOH A O 1 HETATM 9817 O O . HOH G 5 . ? 14.160 63.208 30.117 1.00 26.29 ? 2238 HOH A O 1 HETATM 9818 O O . HOH G 5 . ? 15.889 64.813 31.958 1.00 37.54 ? 2239 HOH A O 1 HETATM 9819 O O . HOH G 5 . ? 18.457 65.062 34.472 1.00 43.35 ? 2240 HOH A O 1 HETATM 9820 O O . HOH G 5 . ? 22.984 55.877 30.795 1.00 13.03 ? 2241 HOH A O 1 HETATM 9821 O O . HOH G 5 . ? 18.016 60.542 24.324 1.00 14.81 ? 2242 HOH A O 1 HETATM 9822 O O . HOH G 5 . ? 14.507 64.597 16.521 1.00 39.77 ? 2243 HOH A O 1 HETATM 9823 O O . HOH G 5 . ? 22.003 70.684 19.081 1.00 34.45 ? 2244 HOH A O 1 HETATM 9824 O O . HOH G 5 . ? 15.602 73.367 5.398 1.00 26.56 ? 2245 HOH A O 1 HETATM 9825 O O . HOH G 5 . ? 15.783 83.184 2.837 1.00 33.64 ? 2246 HOH A O 1 HETATM 9826 O O . HOH G 5 . ? 13.421 84.082 4.029 1.00 35.24 ? 2247 HOH A O 1 HETATM 9827 O O . HOH G 5 . ? 10.659 68.212 -1.899 1.00 35.04 ? 2248 HOH A O 1 HETATM 9828 O O . HOH G 5 . ? 19.527 67.186 -2.840 1.00 20.96 ? 2249 HOH A O 1 HETATM 9829 O O . HOH G 5 . ? 26.784 60.791 -3.351 1.00 8.24 ? 2250 HOH A O 1 HETATM 9830 O O . HOH G 5 . ? 32.581 60.017 -1.870 1.00 7.37 ? 2251 HOH A O 1 HETATM 9831 O O . HOH G 5 . ? 33.098 62.594 0.033 1.00 6.97 ? 2252 HOH A O 1 HETATM 9832 O O . HOH G 5 . ? 37.422 56.940 1.699 1.00 9.31 ? 2253 HOH A O 1 HETATM 9833 O O . HOH G 5 . ? 39.528 55.576 3.033 1.00 16.40 ? 2254 HOH A O 1 HETATM 9834 O O . HOH G 5 . ? 38.682 53.065 2.314 1.00 33.15 ? 2255 HOH A O 1 HETATM 9835 O O . HOH G 5 . ? 35.951 53.007 1.287 1.00 12.32 ? 2256 HOH A O 1 HETATM 9836 O O . HOH G 5 . ? 34.289 52.319 -1.048 1.00 9.36 ? 2257 HOH A O 1 HETATM 9837 O O . HOH G 5 . ? 36.685 51.499 3.759 1.00 12.44 ? 2258 HOH A O 1 HETATM 9838 O O . HOH G 5 . ? 40.065 56.069 5.776 1.00 13.74 ? 2259 HOH A O 1 HETATM 9839 O O . HOH G 5 . ? 42.916 56.698 6.120 1.00 12.42 ? 2260 HOH A O 1 HETATM 9840 O O A HOH G 5 . ? 42.723 56.327 2.803 0.50 10.78 ? 2261 HOH A O 1 HETATM 9841 O O B HOH G 5 . ? 42.089 55.238 1.505 0.50 18.18 ? 2261 HOH A O 1 HETATM 9842 O O . HOH G 5 . ? 40.191 62.629 6.037 1.00 8.63 ? 2262 HOH A O 1 HETATM 9843 O O . HOH G 5 . ? 38.683 62.267 8.408 1.00 9.83 ? 2263 HOH A O 1 HETATM 9844 O O . HOH G 5 . ? 37.648 58.827 11.043 1.00 10.91 ? 2264 HOH A O 1 HETATM 9845 O O . HOH G 5 . ? 36.858 57.589 13.386 1.00 8.36 ? 2265 HOH A O 1 HETATM 9846 O O . HOH G 5 . ? 39.293 57.330 14.870 1.00 7.68 ? 2266 HOH A O 1 HETATM 9847 O O . HOH G 5 . ? 41.142 58.950 13.498 1.00 10.48 ? 2267 HOH A O 1 HETATM 9848 O O . HOH G 5 . ? 43.023 47.959 11.301 1.00 13.94 ? 2268 HOH A O 1 HETATM 9849 O O . HOH G 5 . ? 44.394 45.980 10.110 1.00 13.48 ? 2269 HOH A O 1 HETATM 9850 O O . HOH G 5 . ? 46.635 42.680 9.743 1.00 39.30 ? 2270 HOH A O 1 HETATM 9851 O O . HOH G 5 . ? 48.840 41.727 8.319 1.00 25.71 ? 2271 HOH A O 1 HETATM 9852 O O . HOH G 5 . ? 49.913 44.017 7.084 1.00 15.53 ? 2272 HOH A O 1 HETATM 9853 O O . HOH G 5 . ? 49.345 44.144 4.467 1.00 13.97 ? 2273 HOH A O 1 HETATM 9854 O O . HOH G 5 . ? 51.603 44.306 2.976 1.00 20.01 ? 2274 HOH A O 1 HETATM 9855 O O . HOH G 5 . ? 51.832 46.488 1.352 1.00 10.01 ? 2275 HOH A O 1 HETATM 9856 O O . HOH G 5 . ? 49.835 48.436 1.474 1.00 8.37 ? 2276 HOH A O 1 HETATM 9857 O O . HOH G 5 . ? 47.459 46.013 3.713 1.00 9.40 ? 2277 HOH A O 1 HETATM 9858 O O . HOH G 5 . ? 48.030 41.737 3.634 1.00 16.66 ? 2278 HOH A O 1 HETATM 9859 O O . HOH G 5 . ? 49.592 40.873 1.601 1.00 28.30 ? 2279 HOH A O 1 HETATM 9860 O O . HOH G 5 . ? 50.681 38.355 1.484 1.00 48.03 ? 2280 HOH A O 1 HETATM 9861 O O . HOH G 5 . ? 54.938 38.442 0.443 1.00 30.96 ? 2281 HOH A O 1 HETATM 9862 O O . HOH G 5 . ? 57.967 42.390 1.699 1.00 21.78 ? 2282 HOH A O 1 HETATM 9863 O O . HOH G 5 . ? 57.287 42.826 4.370 1.00 40.87 ? 2283 HOH A O 1 HETATM 9864 O O . HOH G 5 . ? 53.961 45.931 4.703 1.00 35.20 ? 2284 HOH A O 1 HETATM 9865 O O . HOH G 5 . ? 54.111 46.083 8.174 1.00 33.90 ? 2285 HOH A O 1 HETATM 9866 O O . HOH G 5 . ? 52.621 43.604 7.720 1.00 29.80 ? 2286 HOH A O 1 HETATM 9867 O O . HOH G 5 . ? 47.492 40.099 5.925 1.00 30.20 ? 2287 HOH A O 1 HETATM 9868 O O . HOH G 5 . ? 44.639 40.839 7.625 1.00 31.55 ? 2288 HOH A O 1 HETATM 9869 O O . HOH G 5 . ? 42.204 39.643 7.659 1.00 37.95 ? 2289 HOH A O 1 HETATM 9870 O O . HOH G 5 . ? 40.022 39.306 9.036 1.00 22.09 ? 2290 HOH A O 1 HETATM 9871 O O . HOH G 5 . ? 40.673 36.209 8.769 1.00 35.17 ? 2291 HOH A O 1 HETATM 9872 O O . HOH G 5 . ? 39.909 35.357 11.259 1.00 21.26 ? 2292 HOH A O 1 HETATM 9873 O O . HOH G 5 . ? 37.126 33.628 6.097 1.00 39.70 ? 2293 HOH A O 1 HETATM 9874 O O . HOH G 5 . ? 34.844 36.540 3.436 1.00 34.15 ? 2294 HOH A O 1 HETATM 9875 O O . HOH G 5 . ? 37.301 37.491 2.982 1.00 30.31 ? 2295 HOH A O 1 HETATM 9876 O O . HOH G 5 . ? 38.314 40.025 1.786 1.00 10.48 ? 2296 HOH A O 1 HETATM 9877 O O . HOH G 5 . ? 39.990 39.672 -0.351 1.00 19.80 ? 2297 HOH A O 1 HETATM 9878 O O . HOH G 5 . ? 42.528 39.448 -1.376 1.00 23.46 ? 2298 HOH A O 1 HETATM 9879 O O . HOH G 5 . ? 44.494 41.763 -0.426 1.00 12.70 ? 2299 HOH A O 1 HETATM 9880 O O . HOH G 5 . ? 46.050 39.825 -0.077 1.00 24.39 ? 2300 HOH A O 1 HETATM 9881 O O . HOH G 5 . ? 41.615 43.204 8.023 1.00 14.53 ? 2301 HOH A O 1 HETATM 9882 O O . HOH G 5 . ? 44.745 40.232 12.901 1.00 42.40 ? 2302 HOH A O 1 HETATM 9883 O O . HOH G 5 . ? 43.996 42.097 15.630 1.00 44.06 ? 2303 HOH A O 1 HETATM 9884 O O . HOH G 5 . ? 48.827 43.593 18.364 1.00 42.34 ? 2304 HOH A O 1 HETATM 9885 O O . HOH G 5 . ? 52.519 43.847 17.152 1.00 36.31 ? 2305 HOH A O 1 HETATM 9886 O O . HOH G 5 . ? 53.086 44.135 22.957 1.00 34.35 ? 2306 HOH A O 1 HETATM 9887 O O . HOH G 5 . ? 53.847 46.574 23.366 1.00 27.01 ? 2307 HOH A O 1 HETATM 9888 O O . HOH G 5 . ? 56.640 47.235 23.216 1.00 30.66 ? 2308 HOH A O 1 HETATM 9889 O O . HOH G 5 . ? 57.273 48.967 21.278 1.00 20.23 ? 2309 HOH A O 1 HETATM 9890 O O . HOH G 5 . ? 58.763 48.788 19.115 1.00 30.21 ? 2310 HOH A O 1 HETATM 9891 O O . HOH G 5 . ? 59.724 46.234 19.363 1.00 32.88 ? 2311 HOH A O 1 HETATM 9892 O O . HOH G 5 . ? 60.346 50.874 20.254 1.00 30.13 ? 2312 HOH A O 1 HETATM 9893 O O . HOH G 5 . ? 58.460 51.160 22.260 1.00 21.58 ? 2313 HOH A O 1 HETATM 9894 O O . HOH G 5 . ? 59.536 50.800 24.887 1.00 27.94 ? 2314 HOH A O 1 HETATM 9895 O O . HOH G 5 . ? 62.140 50.998 25.657 1.00 43.97 ? 2315 HOH A O 1 HETATM 9896 O O . HOH G 5 . ? 56.036 49.211 27.314 1.00 31.30 ? 2316 HOH A O 1 HETATM 9897 O O . HOH G 5 . ? 58.894 56.539 31.309 1.00 39.15 ? 2317 HOH A O 1 HETATM 9898 O O . HOH G 5 . ? 50.796 55.364 34.933 1.00 36.29 ? 2318 HOH A O 1 HETATM 9899 O O . HOH G 5 . ? 62.139 56.520 17.814 1.00 39.77 ? 2319 HOH A O 1 HETATM 9900 O O A HOH G 5 . ? 60.548 56.982 15.801 0.50 18.68 ? 2320 HOH A O 1 HETATM 9901 O O B HOH G 5 . ? 61.487 59.098 15.032 0.50 15.68 ? 2320 HOH A O 1 HETATM 9902 O O . HOH G 5 . ? 63.412 59.825 16.920 1.00 35.67 ? 2321 HOH A O 1 HETATM 9903 O O . HOH G 5 . ? 63.823 62.336 16.489 1.00 31.54 ? 2322 HOH A O 1 HETATM 9904 O O . HOH G 5 . ? 60.925 63.669 15.433 1.00 24.46 ? 2323 HOH A O 1 HETATM 9905 O O . HOH G 5 . ? 62.941 57.580 13.137 1.00 43.42 ? 2324 HOH A O 1 HETATM 9906 O O . HOH G 5 . ? 63.096 56.147 9.918 1.00 45.44 ? 2325 HOH A O 1 HETATM 9907 O O . HOH G 5 . ? 60.261 54.192 14.804 1.00 29.69 ? 2326 HOH A O 1 HETATM 9908 O O . HOH G 5 . ? 52.102 50.464 6.390 1.00 9.15 ? 2327 HOH A O 1 HETATM 9909 O O . HOH G 5 . ? 58.609 42.097 17.111 1.00 37.92 ? 2328 HOH A O 1 HETATM 9910 O O . HOH G 5 . ? 59.259 39.614 -3.974 1.00 36.38 ? 2329 HOH A O 1 HETATM 9911 O O . HOH G 5 . ? 63.498 44.651 -6.645 1.00 13.45 ? 2330 HOH A O 1 HETATM 9912 O O . HOH G 5 . ? 64.368 39.317 -10.157 1.00 18.45 ? 2331 HOH A O 1 HETATM 9913 O O . HOH G 5 . ? 66.833 38.384 -9.520 1.00 29.28 ? 2332 HOH A O 1 HETATM 9914 O O . HOH G 5 . ? 67.993 39.166 -7.422 1.00 37.98 ? 2333 HOH A O 1 HETATM 9915 O O . HOH G 5 . ? 71.163 40.083 -9.454 1.00 38.49 ? 2334 HOH A O 1 HETATM 9916 O O . HOH G 5 . ? 73.145 43.915 -12.032 1.00 41.31 ? 2335 HOH A O 1 HETATM 9917 O O . HOH G 5 . ? 71.012 43.395 -15.188 1.00 35.94 ? 2336 HOH A O 1 HETATM 9918 O O . HOH G 5 . ? 69.112 41.764 -17.332 1.00 30.17 ? 2337 HOH A O 1 HETATM 9919 O O . HOH G 5 . ? 68.758 47.098 -16.514 1.00 32.03 ? 2338 HOH A O 1 HETATM 9920 O O . HOH G 5 . ? 72.828 47.478 -17.250 1.00 33.36 ? 2339 HOH A O 1 HETATM 9921 O O . HOH G 5 . ? 74.402 49.242 -18.654 1.00 37.55 ? 2340 HOH A O 1 HETATM 9922 O O . HOH G 5 . ? 71.706 49.649 -20.015 1.00 48.32 ? 2341 HOH A O 1 HETATM 9923 O O . HOH G 5 . ? 74.310 52.734 -18.123 1.00 33.16 ? 2342 HOH A O 1 HETATM 9924 O O . HOH G 5 . ? 75.169 52.352 -15.455 1.00 36.93 ? 2343 HOH A O 1 HETATM 9925 O O . HOH G 5 . ? 73.779 54.217 -13.749 1.00 42.90 ? 2344 HOH A O 1 HETATM 9926 O O . HOH G 5 . ? 76.316 54.245 -10.020 1.00 30.20 ? 2345 HOH A O 1 HETATM 9927 O O . HOH G 5 . ? 72.265 55.472 -9.079 1.00 28.86 ? 2346 HOH A O 1 HETATM 9928 O O . HOH G 5 . ? 72.923 56.182 -6.492 1.00 29.31 ? 2347 HOH A O 1 HETATM 9929 O O . HOH G 5 . ? 74.604 58.308 -7.166 1.00 33.89 ? 2348 HOH A O 1 HETATM 9930 O O . HOH G 5 . ? 73.753 61.062 -6.052 1.00 32.94 ? 2349 HOH A O 1 HETATM 9931 O O . HOH G 5 . ? 70.172 53.690 -9.581 1.00 30.41 ? 2350 HOH A O 1 HETATM 9932 O O . HOH G 5 . ? 68.716 56.908 -16.476 1.00 37.93 ? 2351 HOH A O 1 HETATM 9933 O O . HOH G 5 . ? 66.405 62.561 -13.045 1.00 16.00 ? 2352 HOH A O 1 HETATM 9934 O O . HOH G 5 . ? 60.996 59.668 -8.118 1.00 7.54 ? 2353 HOH A O 1 HETATM 9935 O O . HOH G 5 . ? 59.427 60.601 -6.103 1.00 14.78 ? 2354 HOH A O 1 HETATM 9936 O O . HOH G 5 . ? 53.651 59.753 -9.360 1.00 13.08 ? 2355 HOH A O 1 HETATM 9937 O O . HOH G 5 . ? 55.592 59.281 -11.443 1.00 8.94 ? 2356 HOH A O 1 HETATM 9938 O O . HOH G 5 . ? 60.474 61.032 -18.044 1.00 9.54 ? 2357 HOH A O 1 HETATM 9939 O O . HOH G 5 . ? 53.609 64.822 -19.843 1.00 9.93 ? 2358 HOH A O 1 HETATM 9940 O O . HOH G 5 . ? 46.934 55.786 -25.444 1.00 15.41 ? 2359 HOH A O 1 HETATM 9941 O O . HOH G 5 . ? 43.885 54.842 -26.642 1.00 29.40 ? 2360 HOH A O 1 HETATM 9942 O O . HOH G 5 . ? 52.962 51.992 -38.198 1.00 40.43 ? 2361 HOH A O 1 HETATM 9943 O O . HOH G 5 . ? 52.051 45.856 -37.743 1.00 43.47 ? 2362 HOH A O 1 HETATM 9944 O O . HOH G 5 . ? 53.406 43.840 -36.703 1.00 66.09 ? 2363 HOH A O 1 HETATM 9945 O O . HOH G 5 . ? 56.671 46.164 -17.310 1.00 14.41 ? 2364 HOH A O 1 HETATM 9946 O O . HOH G 5 . ? 51.659 41.097 -12.999 1.00 29.88 ? 2365 HOH A O 1 HETATM 9947 O O . HOH G 5 . ? 50.867 40.412 -15.383 1.00 35.24 ? 2366 HOH A O 1 HETATM 9948 O O . HOH G 5 . ? 53.629 39.110 -12.327 1.00 36.75 ? 2367 HOH A O 1 HETATM 9949 O O . HOH G 5 . ? 63.271 34.462 -9.535 1.00 34.19 ? 2368 HOH A O 1 HETATM 9950 O O . HOH G 5 . ? 66.276 35.337 -12.844 1.00 34.68 ? 2369 HOH A O 1 HETATM 9951 O O . HOH G 5 . ? 63.806 50.168 -13.786 1.00 13.79 ? 2370 HOH A O 1 HETATM 9952 O O . HOH G 5 . ? 45.969 70.820 0.022 1.00 15.89 ? 2371 HOH A O 1 HETATM 9953 O O . HOH G 5 . ? 40.703 74.414 -1.984 1.00 39.39 ? 2372 HOH A O 1 HETATM 9954 O O . HOH G 5 . ? 37.828 73.208 -2.246 1.00 11.79 ? 2373 HOH A O 1 HETATM 9955 O O . HOH G 5 . ? 37.014 71.751 -4.535 1.00 7.32 ? 2374 HOH A O 1 HETATM 9956 O O . HOH G 5 . ? 36.524 72.471 0.258 1.00 7.73 ? 2375 HOH A O 1 HETATM 9957 O O . HOH G 5 . ? 33.273 78.440 -5.206 1.00 12.04 ? 2376 HOH A O 1 HETATM 9958 O O . HOH G 5 . ? 31.314 76.660 -6.362 1.00 9.26 ? 2377 HOH A O 1 HETATM 9959 O O . HOH G 5 . ? 27.809 68.428 -21.489 1.00 39.15 ? 2378 HOH A O 1 HETATM 9960 O O . HOH G 5 . ? 20.596 66.024 -19.662 1.00 11.20 ? 2379 HOH A O 1 HETATM 9961 O O . HOH G 5 . ? 16.529 67.523 -19.975 1.00 19.74 ? 2380 HOH A O 1 HETATM 9962 O O . HOH G 5 . ? 14.702 67.614 -22.785 1.00 29.50 ? 2381 HOH A O 1 HETATM 9963 O O . HOH G 5 . ? 17.260 69.989 -23.425 1.00 19.54 ? 2382 HOH A O 1 HETATM 9964 O O . HOH G 5 . ? 17.053 66.898 -25.896 1.00 27.16 ? 2383 HOH A O 1 HETATM 9965 O O . HOH G 5 . ? 18.514 64.932 -27.026 1.00 16.17 ? 2384 HOH A O 1 HETATM 9966 O O . HOH G 5 . ? 15.099 63.472 -25.852 1.00 20.99 ? 2385 HOH A O 1 HETATM 9967 O O . HOH G 5 . ? 13.917 60.767 -22.547 1.00 13.99 ? 2386 HOH A O 1 HETATM 9968 O O . HOH G 5 . ? 13.500 58.070 -22.056 1.00 29.71 ? 2387 HOH A O 1 HETATM 9969 O O . HOH G 5 . ? 13.652 55.613 -22.354 1.00 36.93 ? 2388 HOH A O 1 HETATM 9970 O O . HOH G 5 . ? 10.522 57.804 -21.166 1.00 36.55 ? 2389 HOH A O 1 HETATM 9971 O O . HOH G 5 . ? 9.874 60.326 -20.412 1.00 36.83 ? 2390 HOH A O 1 HETATM 9972 O O . HOH G 5 . ? 11.464 61.228 -18.250 1.00 21.30 ? 2391 HOH A O 1 HETATM 9973 O O . HOH G 5 . ? 13.398 62.293 -20.046 1.00 19.06 ? 2392 HOH A O 1 HETATM 9974 O O . HOH G 5 . ? 10.110 62.693 -14.927 1.00 30.43 ? 2393 HOH A O 1 HETATM 9975 O O . HOH G 5 . ? 8.522 60.540 -15.832 1.00 33.72 ? 2394 HOH A O 1 HETATM 9976 O O . HOH G 5 . ? 17.112 70.097 -16.256 1.00 10.41 ? 2395 HOH A O 1 HETATM 9977 O O . HOH G 5 . ? 16.021 71.823 -19.030 1.00 15.89 ? 2396 HOH A O 1 HETATM 9978 O O . HOH G 5 . ? 12.862 74.688 -18.957 1.00 31.35 ? 2397 HOH A O 1 HETATM 9979 O O . HOH G 5 . ? 12.359 77.735 -18.933 1.00 42.87 ? 2398 HOH A O 1 HETATM 9980 O O . HOH G 5 . ? 16.180 74.979 -23.784 1.00 38.56 ? 2399 HOH A O 1 HETATM 9981 O O . HOH G 5 . ? 16.709 77.512 -25.775 1.00 36.65 ? 2400 HOH A O 1 HETATM 9982 O O . HOH G 5 . ? 19.276 78.742 -25.588 1.00 35.44 ? 2401 HOH A O 1 HETATM 9983 O O . HOH G 5 . ? 20.296 77.296 -27.608 1.00 36.82 ? 2402 HOH A O 1 HETATM 9984 O O . HOH G 5 . ? 22.705 77.081 -27.592 1.00 25.58 ? 2403 HOH A O 1 HETATM 9985 O O . HOH G 5 . ? 23.134 78.270 -24.834 1.00 13.92 ? 2404 HOH A O 1 HETATM 9986 O O . HOH G 5 . ? 20.975 79.271 -23.550 1.00 20.04 ? 2405 HOH A O 1 HETATM 9987 O O . HOH G 5 . ? 22.924 78.379 -30.403 1.00 23.00 ? 2406 HOH A O 1 HETATM 9988 O O . HOH G 5 . ? 20.687 80.096 -33.557 1.00 39.65 ? 2407 HOH A O 1 HETATM 9989 O O . HOH G 5 . ? 22.024 80.090 -35.910 1.00 22.30 ? 2408 HOH A O 1 HETATM 9990 O O . HOH G 5 . ? 21.436 82.126 -37.969 1.00 30.13 ? 2409 HOH A O 1 HETATM 9991 O O . HOH G 5 . ? 23.223 82.352 -40.478 1.00 20.31 ? 2410 HOH A O 1 HETATM 9992 O O . HOH G 5 . ? 23.189 84.792 -41.547 1.00 43.52 ? 2411 HOH A O 1 HETATM 9993 O O . HOH G 5 . ? 24.053 87.275 -40.895 1.00 33.28 ? 2412 HOH A O 1 HETATM 9994 O O . HOH G 5 . ? 25.780 87.726 -42.891 1.00 36.82 ? 2413 HOH A O 1 HETATM 9995 O O . HOH G 5 . ? 28.032 87.740 -41.618 1.00 23.35 ? 2414 HOH A O 1 HETATM 9996 O O . HOH G 5 . ? 28.037 90.655 -42.512 1.00 25.77 ? 2415 HOH A O 1 HETATM 9997 O O . HOH G 5 . ? 32.379 88.946 -43.081 1.00 21.88 ? 2416 HOH A O 1 HETATM 9998 O O . HOH G 5 . ? 34.076 86.680 -43.684 1.00 29.70 ? 2417 HOH A O 1 HETATM 9999 O O . HOH G 5 . ? 36.524 85.722 -43.046 1.00 31.74 ? 2418 HOH A O 1 HETATM 10000 O O . HOH G 5 . ? 38.865 86.279 -41.695 1.00 26.73 ? 2419 HOH A O 1 HETATM 10001 O O . HOH G 5 . ? 40.989 86.659 -43.916 1.00 40.13 ? 2420 HOH A O 1 HETATM 10002 O O . HOH G 5 . ? 43.361 86.586 -43.226 1.00 25.50 ? 2421 HOH A O 1 HETATM 10003 O O . HOH G 5 . ? 42.028 87.609 -41.059 1.00 13.30 ? 2422 HOH A O 1 HETATM 10004 O O . HOH G 5 . ? 43.468 88.267 -38.768 1.00 11.68 ? 2423 HOH A O 1 HETATM 10005 O O . HOH G 5 . ? 43.256 93.712 -37.737 1.00 17.87 ? 2424 HOH A O 1 HETATM 10006 O O . HOH G 5 . ? 45.789 94.787 -37.868 1.00 26.55 ? 2425 HOH A O 1 HETATM 10007 O O . HOH G 5 . ? 45.212 97.204 -38.569 1.00 43.33 ? 2426 HOH A O 1 HETATM 10008 O O . HOH G 5 . ? 43.029 97.947 -37.255 1.00 29.10 ? 2427 HOH A O 1 HETATM 10009 O O . HOH G 5 . ? 40.522 96.245 -37.587 1.00 24.47 ? 2428 HOH A O 1 HETATM 10010 O O . HOH G 5 . ? 41.158 94.664 -39.369 1.00 18.12 ? 2429 HOH A O 1 HETATM 10011 O O . HOH G 5 . ? 41.945 96.321 -41.643 1.00 31.24 ? 2430 HOH A O 1 HETATM 10012 O O . HOH G 5 . ? 45.882 96.894 -43.884 1.00 24.47 ? 2431 HOH A O 1 HETATM 10013 O O . HOH G 5 . ? 48.388 95.961 -44.357 1.00 34.35 ? 2432 HOH A O 1 HETATM 10014 O O . HOH G 5 . ? 47.694 95.188 -41.062 1.00 45.22 ? 2433 HOH A O 1 HETATM 10015 O O . HOH G 5 . ? 48.283 93.749 -37.969 1.00 36.88 ? 2434 HOH A O 1 HETATM 10016 O O . HOH G 5 . ? 48.452 97.801 -33.734 1.00 29.15 ? 2435 HOH A O 1 HETATM 10017 O O A HOH G 5 . ? 46.594 99.784 -31.306 0.50 20.64 ? 2436 HOH A O 1 HETATM 10018 O O B HOH G 5 . ? 47.376 99.841 -32.880 0.50 18.00 ? 2436 HOH A O 1 HETATM 10019 O O . HOH G 5 . ? 44.668 101.532 -32.750 1.00 37.82 ? 2437 HOH A O 1 HETATM 10020 O O . HOH G 5 . ? 39.883 99.829 -32.009 1.00 29.14 ? 2438 HOH A O 1 HETATM 10021 O O . HOH G 5 . ? 48.343 98.262 -28.691 1.00 30.24 ? 2439 HOH A O 1 HETATM 10022 O O . HOH G 5 . ? 52.120 97.967 -30.500 1.00 30.08 ? 2440 HOH A O 1 HETATM 10023 O O . HOH G 5 . ? 53.451 97.193 -32.570 1.00 52.29 ? 2441 HOH A O 1 HETATM 10024 O O . HOH G 5 . ? 53.677 93.950 -33.534 1.00 27.25 ? 2442 HOH A O 1 HETATM 10025 O O . HOH G 5 . ? 38.515 83.385 -39.868 1.00 28.41 ? 2443 HOH A O 1 HETATM 10026 O O . HOH G 5 . ? 36.842 82.397 -41.518 1.00 44.63 ? 2444 HOH A O 1 HETATM 10027 O O . HOH G 5 . ? 34.704 81.048 -41.673 1.00 36.56 ? 2445 HOH A O 1 HETATM 10028 O O . HOH G 5 . ? 35.689 77.299 -42.925 1.00 24.51 ? 2446 HOH A O 1 HETATM 10029 O O . HOH G 5 . ? 37.554 75.417 -42.286 1.00 18.66 ? 2447 HOH A O 1 HETATM 10030 O O . HOH G 5 . ? 39.691 75.441 -40.345 1.00 15.61 ? 2448 HOH A O 1 HETATM 10031 O O . HOH G 5 . ? 38.736 69.139 -38.090 1.00 14.01 ? 2449 HOH A O 1 HETATM 10032 O O . HOH G 5 . ? 39.343 69.045 -35.378 1.00 15.69 ? 2450 HOH A O 1 HETATM 10033 O O . HOH G 5 . ? 43.082 65.295 -39.592 1.00 35.81 ? 2451 HOH A O 1 HETATM 10034 O O . HOH G 5 . ? 43.801 62.370 -39.997 1.00 35.37 ? 2452 HOH A O 1 HETATM 10035 O O . HOH G 5 . ? 45.415 61.255 -43.846 1.00 39.72 ? 2453 HOH A O 1 HETATM 10036 O O . HOH G 5 . ? 36.658 62.915 -45.701 1.00 38.14 ? 2454 HOH A O 1 HETATM 10037 O O . HOH G 5 . ? 34.181 66.342 -42.721 1.00 27.84 ? 2455 HOH A O 1 HETATM 10038 O O . HOH G 5 . ? 30.841 69.461 -45.433 1.00 42.55 ? 2456 HOH A O 1 HETATM 10039 O O . HOH G 5 . ? 28.241 68.968 -46.346 1.00 48.58 ? 2457 HOH A O 1 HETATM 10040 O O . HOH G 5 . ? 29.065 72.164 -42.179 1.00 33.64 ? 2458 HOH A O 1 HETATM 10041 O O . HOH G 5 . ? 28.957 69.603 -39.693 1.00 20.47 ? 2459 HOH A O 1 HETATM 10042 O O . HOH G 5 . ? 24.695 71.477 -39.768 1.00 27.30 ? 2460 HOH A O 1 HETATM 10043 O O . HOH G 5 . ? 22.206 70.685 -36.620 1.00 34.06 ? 2461 HOH A O 1 HETATM 10044 O O . HOH G 5 . ? 18.887 67.804 -30.918 1.00 44.87 ? 2462 HOH A O 1 HETATM 10045 O O . HOH G 5 . ? 18.548 70.124 -30.053 1.00 32.77 ? 2463 HOH A O 1 HETATM 10046 O O . HOH G 5 . ? 16.379 74.527 -28.402 1.00 41.91 ? 2464 HOH A O 1 HETATM 10047 O O . HOH G 5 . ? 30.256 74.826 -29.182 1.00 13.06 ? 2465 HOH A O 1 HETATM 10048 O O . HOH G 5 . ? 32.422 77.553 -29.658 1.00 12.16 ? 2466 HOH A O 1 HETATM 10049 O O . HOH G 5 . ? 28.914 81.653 -35.719 1.00 15.97 ? 2467 HOH A O 1 HETATM 10050 O O . HOH G 5 . ? 28.057 84.300 -35.508 1.00 14.64 ? 2468 HOH A O 1 HETATM 10051 O O . HOH G 5 . ? 23.146 88.590 -38.049 1.00 27.73 ? 2469 HOH A O 1 HETATM 10052 O O . HOH G 5 . ? 28.719 93.654 -38.514 1.00 29.17 ? 2470 HOH A O 1 HETATM 10053 O O . HOH G 5 . ? 30.767 94.091 -40.367 1.00 40.43 ? 2471 HOH A O 1 HETATM 10054 O O . HOH G 5 . ? 31.806 92.333 -36.744 1.00 21.23 ? 2472 HOH A O 1 HETATM 10055 O O . HOH G 5 . ? 26.529 96.514 -37.584 1.00 42.83 ? 2473 HOH A O 1 HETATM 10056 O O . HOH G 5 . ? 35.697 89.343 -44.998 1.00 32.90 ? 2474 HOH A O 1 HETATM 10057 O O . HOH G 5 . ? 39.920 83.319 -44.099 1.00 50.38 ? 2475 HOH A O 1 HETATM 10058 O O . HOH G 5 . ? 31.375 78.908 -42.842 1.00 25.21 ? 2476 HOH A O 1 HETATM 10059 O O . HOH G 5 . ? 29.696 81.182 -43.109 1.00 28.87 ? 2477 HOH A O 1 HETATM 10060 O O . HOH G 5 . ? 26.011 81.116 -42.731 1.00 31.90 ? 2478 HOH A O 1 HETATM 10061 O O . HOH G 5 . ? 23.068 78.307 -42.086 1.00 32.97 ? 2479 HOH A O 1 HETATM 10062 O O . HOH G 5 . ? 26.295 76.214 -39.237 1.00 27.68 ? 2480 HOH A O 1 HETATM 10063 O O . HOH G 5 . ? 27.293 76.074 -41.611 1.00 44.83 ? 2481 HOH A O 1 HETATM 10064 O O . HOH G 5 . ? 23.837 65.283 -43.537 1.00 36.46 ? 2482 HOH A O 1 HETATM 10065 O O . HOH G 5 . ? 12.043 49.084 25.360 1.00 30.91 ? 2483 HOH A O 1 HETATM 10066 O O . HOH G 5 . ? 9.864 49.227 23.209 1.00 40.19 ? 2484 HOH A O 1 HETATM 10067 O O . HOH G 5 . ? 22.507 56.753 -34.105 1.00 14.78 ? 2485 HOH A O 1 HETATM 10068 O O . HOH G 5 . ? 19.915 51.546 -30.939 1.00 31.52 ? 2486 HOH A O 1 HETATM 10069 O O . HOH G 5 . ? 20.049 52.437 -27.298 1.00 21.97 ? 2487 HOH A O 1 HETATM 10070 O O . HOH G 5 . ? 23.156 48.912 -27.214 1.00 43.52 ? 2488 HOH A O 1 HETATM 10071 O O . HOH G 5 . ? 26.426 44.266 -27.286 1.00 23.34 ? 2489 HOH A O 1 HETATM 10072 O O . HOH G 5 . ? 30.261 39.195 -27.277 1.00 19.74 ? 2490 HOH A O 1 HETATM 10073 O O . HOH G 5 . ? 17.968 48.709 -20.013 1.00 33.85 ? 2491 HOH A O 1 HETATM 10074 O O . HOH G 5 . ? 17.031 50.852 -19.468 1.00 23.72 ? 2492 HOH A O 1 HETATM 10075 O O . HOH G 5 . ? 16.537 52.823 -22.341 1.00 26.32 ? 2493 HOH A O 1 HETATM 10076 O O . HOH G 5 . ? 15.719 52.974 -25.432 1.00 37.35 ? 2494 HOH A O 1 HETATM 10077 O O . HOH G 5 . ? 16.771 58.767 -31.190 1.00 27.88 ? 2495 HOH A O 1 HETATM 10078 O O . HOH G 5 . ? 14.078 57.721 -1.359 1.00 18.72 ? 2496 HOH A O 1 HETATM 10079 O O . HOH G 5 . ? 13.398 53.567 1.739 1.00 14.93 ? 2497 HOH A O 1 HETATM 10080 O O . HOH G 5 . ? 13.804 54.012 4.322 1.00 14.01 ? 2498 HOH A O 1 HETATM 10081 O O . HOH G 5 . ? 12.476 56.136 5.176 1.00 14.10 ? 2499 HOH A O 1 HETATM 10082 O O . HOH G 5 . ? 9.018 50.320 8.137 1.00 26.40 ? 2500 HOH A O 1 HETATM 10083 O O . HOH G 5 . ? 11.818 51.311 14.208 1.00 13.26 ? 2501 HOH A O 1 HETATM 10084 O O . HOH G 5 . ? 13.948 48.950 15.291 1.00 12.17 ? 2502 HOH A O 1 HETATM 10085 O O . HOH G 5 . ? 10.242 50.643 18.815 1.00 19.17 ? 2503 HOH A O 1 HETATM 10086 O O . HOH G 5 . ? 9.359 52.219 16.791 1.00 17.23 ? 2504 HOH A O 1 HETATM 10087 O O . HOH G 5 . ? 8.239 48.301 19.064 1.00 33.02 ? 2505 HOH A O 1 HETATM 10088 O O . HOH G 5 . ? 6.157 46.521 15.834 1.00 39.53 ? 2506 HOH A O 1 HETATM 10089 O O . HOH G 5 . ? 11.452 33.648 22.994 1.00 39.53 ? 2507 HOH A O 1 HETATM 10090 O O . HOH G 5 . ? 36.830 29.138 12.988 1.00 31.01 ? 2508 HOH A O 1 HETATM 10091 O O . HOH G 5 . ? 30.830 57.149 4.466 1.00 18.27 ? 2509 HOH A O 1 HETATM 10092 O O . HOH G 5 . ? 41.790 79.207 -23.361 1.00 28.23 ? 2510 HOH A O 1 HETATM 10093 O O . HOH G 5 . ? 39.128 82.063 -21.922 1.00 33.42 ? 2511 HOH A O 1 HETATM 10094 O O . HOH G 5 . ? 37.005 92.305 -18.122 1.00 32.05 ? 2512 HOH A O 1 HETATM 10095 O O . HOH G 5 . ? 36.976 95.896 -20.534 1.00 37.44 ? 2513 HOH A O 1 HETATM 10096 O O . HOH G 5 . ? 35.110 97.518 -18.146 1.00 36.36 ? 2514 HOH A O 1 HETATM 10097 O O . HOH G 5 . ? 27.829 102.031 -19.240 1.00 26.52 ? 2515 HOH A O 1 HETATM 10098 O O . HOH G 5 . ? 25.331 95.883 -16.282 1.00 41.76 ? 2516 HOH A O 1 HETATM 10099 O O . HOH G 5 . ? 21.957 88.242 -22.593 1.00 45.46 ? 2517 HOH A O 1 HETATM 10100 O O . HOH G 5 . ? 46.553 70.147 -36.603 1.00 15.37 ? 2518 HOH A O 1 HETATM 10101 O O . HOH G 5 . ? 48.986 69.101 -36.873 1.00 24.22 ? 2519 HOH A O 1 HETATM 10102 O O . HOH G 5 . ? 30.916 43.720 40.633 1.00 41.91 ? 2520 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 30 GLN GLN A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ASP 204 204 204 ASP ASP A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASP 341 341 341 ASP ASP A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 1045 SER SER A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 1046 1 NAG NAG A . C 3 ZN 1 1047 1 ZN ZN A . D 4 MPD 1 1048 1 MPD MPD A . E 4 MPD 1 1049 2 MPD MPD A . F 4 MPD 1 1050 4 MPD MPD A . G 5 HOH 1 1051 1 HOH HOH A . G 5 HOH 2 1052 2 HOH HOH A . G 5 HOH 3 1053 3 HOH HOH A . G 5 HOH 4 1054 4 HOH HOH A . G 5 HOH 5 1055 5 HOH HOH A . G 5 HOH 6 1056 6 HOH HOH A . G 5 HOH 7 1057 7 HOH HOH A . G 5 HOH 8 1058 8 HOH HOH A . G 5 HOH 9 1059 9 HOH HOH A . G 5 HOH 10 1060 10 HOH HOH A . G 5 HOH 11 1061 11 HOH HOH A . G 5 HOH 12 1062 12 HOH HOH A . G 5 HOH 13 1063 13 HOH HOH A . G 5 HOH 14 1064 14 HOH HOH A . G 5 HOH 15 1065 15 HOH HOH A . G 5 HOH 16 1066 16 HOH HOH A . G 5 HOH 17 1067 17 HOH HOH A . G 5 HOH 18 1068 18 HOH HOH A . G 5 HOH 19 1069 19 HOH HOH A . G 5 HOH 20 1070 20 HOH HOH A . G 5 HOH 21 1071 21 HOH HOH A . G 5 HOH 22 1072 22 HOH HOH A . G 5 HOH 23 1073 23 HOH HOH A . G 5 HOH 24 1074 24 HOH HOH A . G 5 HOH 25 1075 25 HOH HOH A . G 5 HOH 26 1076 26 HOH HOH A . G 5 HOH 27 1077 27 HOH HOH A . G 5 HOH 28 1078 28 HOH HOH A . G 5 HOH 29 1079 29 HOH HOH A . G 5 HOH 30 1080 30 HOH HOH A . G 5 HOH 31 1081 31 HOH HOH A . G 5 HOH 32 1082 32 HOH HOH A . G 5 HOH 33 1083 33 HOH HOH A . G 5 HOH 34 1084 34 HOH HOH A . G 5 HOH 35 1085 35 HOH HOH A . G 5 HOH 36 1086 36 HOH HOH A . G 5 HOH 37 1087 37 HOH HOH A . G 5 HOH 38 1088 38 HOH HOH A . G 5 HOH 39 1089 39 HOH HOH A . G 5 HOH 40 1090 40 HOH HOH A . G 5 HOH 41 1091 41 HOH HOH A . G 5 HOH 42 1092 42 HOH HOH A . G 5 HOH 43 1093 43 HOH HOH A . G 5 HOH 44 1094 44 HOH HOH A . G 5 HOH 45 1095 45 HOH HOH A . G 5 HOH 46 1096 46 HOH HOH A . G 5 HOH 47 1097 47 HOH HOH A . G 5 HOH 48 1098 48 HOH HOH A . G 5 HOH 49 1099 49 HOH HOH A . G 5 HOH 50 1100 50 HOH HOH A . G 5 HOH 51 1101 51 HOH HOH A . G 5 HOH 52 1102 52 HOH HOH A . G 5 HOH 53 1103 53 HOH HOH A . G 5 HOH 54 1104 54 HOH HOH A . G 5 HOH 55 1105 55 HOH HOH A . G 5 HOH 56 1106 56 HOH HOH A . G 5 HOH 57 1107 57 HOH HOH A . G 5 HOH 58 1108 58 HOH HOH A . G 5 HOH 59 1109 59 HOH HOH A . G 5 HOH 60 1110 60 HOH HOH A . G 5 HOH 61 1111 61 HOH HOH A . G 5 HOH 62 1112 62 HOH HOH A . G 5 HOH 63 1113 63 HOH HOH A . G 5 HOH 64 1114 64 HOH HOH A . G 5 HOH 65 1115 65 HOH HOH A . G 5 HOH 66 1116 66 HOH HOH A . G 5 HOH 67 1117 67 HOH HOH A . G 5 HOH 68 1118 68 HOH HOH A . G 5 HOH 69 1119 69 HOH HOH A . G 5 HOH 70 1120 70 HOH HOH A . G 5 HOH 71 1121 71 HOH HOH A . G 5 HOH 72 1122 72 HOH HOH A . G 5 HOH 73 1123 73 HOH HOH A . G 5 HOH 74 1124 74 HOH HOH A . G 5 HOH 75 1125 75 HOH HOH A . G 5 HOH 76 1126 76 HOH HOH A . G 5 HOH 77 1127 77 HOH HOH A . G 5 HOH 78 1128 78 HOH HOH A . G 5 HOH 79 1129 79 HOH HOH A . G 5 HOH 80 1130 80 HOH HOH A . G 5 HOH 81 1131 81 HOH HOH A . G 5 HOH 82 1132 82 HOH HOH A . G 5 HOH 83 1133 83 HOH HOH A . G 5 HOH 84 1134 84 HOH HOH A . G 5 HOH 85 1135 85 HOH HOH A . G 5 HOH 86 1136 86 HOH HOH A . G 5 HOH 87 1137 87 HOH HOH A . G 5 HOH 88 1138 88 HOH HOH A . G 5 HOH 89 1139 89 HOH HOH A . G 5 HOH 90 1140 90 HOH HOH A . G 5 HOH 91 1141 91 HOH HOH A . G 5 HOH 92 1142 92 HOH HOH A . G 5 HOH 93 1143 93 HOH HOH A . G 5 HOH 94 1144 94 HOH HOH A . G 5 HOH 95 1145 95 HOH HOH A . G 5 HOH 96 1146 96 HOH HOH A . G 5 HOH 97 1147 97 HOH HOH A . G 5 HOH 98 1148 98 HOH HOH A . G 5 HOH 99 1149 99 HOH HOH A . G 5 HOH 100 1150 100 HOH HOH A . G 5 HOH 101 1151 101 HOH HOH A . G 5 HOH 102 1152 102 HOH HOH A . G 5 HOH 103 1153 103 HOH HOH A . G 5 HOH 104 1154 104 HOH HOH A . G 5 HOH 105 1155 105 HOH HOH A . G 5 HOH 106 1156 106 HOH HOH A . G 5 HOH 107 1157 107 HOH HOH A . G 5 HOH 108 1158 108 HOH HOH A . G 5 HOH 109 1159 109 HOH HOH A . G 5 HOH 110 1160 110 HOH HOH A . G 5 HOH 111 1161 111 HOH HOH A . G 5 HOH 112 1162 112 HOH HOH A . G 5 HOH 113 1163 113 HOH HOH A . G 5 HOH 114 1164 114 HOH HOH A . G 5 HOH 115 1165 115 HOH HOH A . G 5 HOH 116 1166 116 HOH HOH A . G 5 HOH 117 1167 117 HOH HOH A . G 5 HOH 118 1168 118 HOH HOH A . G 5 HOH 119 1169 119 HOH HOH A . G 5 HOH 120 1170 120 HOH HOH A . G 5 HOH 121 1171 121 HOH HOH A . G 5 HOH 122 1172 122 HOH HOH A . G 5 HOH 123 1173 123 HOH HOH A . G 5 HOH 124 1174 124 HOH HOH A . G 5 HOH 125 1175 125 HOH HOH A . G 5 HOH 126 1176 126 HOH HOH A . G 5 HOH 127 1177 127 HOH HOH A . G 5 HOH 128 1178 128 HOH HOH A . G 5 HOH 129 1179 129 HOH HOH A . G 5 HOH 130 1180 130 HOH HOH A . G 5 HOH 131 1181 131 HOH HOH A . G 5 HOH 132 1182 132 HOH HOH A . G 5 HOH 133 1183 133 HOH HOH A . G 5 HOH 134 1184 134 HOH HOH A . G 5 HOH 135 1185 135 HOH HOH A . G 5 HOH 136 1186 136 HOH HOH A . G 5 HOH 137 1187 137 HOH HOH A . G 5 HOH 138 1188 138 HOH HOH A . G 5 HOH 139 1189 139 HOH HOH A . G 5 HOH 140 1190 140 HOH HOH A . G 5 HOH 141 1191 141 HOH HOH A . G 5 HOH 142 1192 142 HOH HOH A . G 5 HOH 143 1193 143 HOH HOH A . G 5 HOH 144 1194 144 HOH HOH A . G 5 HOH 145 1195 145 HOH HOH A . G 5 HOH 146 1196 146 HOH HOH A . G 5 HOH 147 1197 147 HOH HOH A . G 5 HOH 148 1198 148 HOH HOH A . G 5 HOH 149 1199 149 HOH HOH A . G 5 HOH 150 1200 150 HOH HOH A . G 5 HOH 151 1201 151 HOH HOH A . G 5 HOH 152 1202 152 HOH HOH A . G 5 HOH 153 1203 153 HOH HOH A . G 5 HOH 154 1204 154 HOH HOH A . G 5 HOH 155 1205 155 HOH HOH A . G 5 HOH 156 1206 156 HOH HOH A . G 5 HOH 157 1207 157 HOH HOH A . G 5 HOH 158 1208 158 HOH HOH A . G 5 HOH 159 1209 159 HOH HOH A . G 5 HOH 160 1210 160 HOH HOH A . G 5 HOH 161 1211 161 HOH HOH A . G 5 HOH 162 1212 162 HOH HOH A . G 5 HOH 163 1213 163 HOH HOH A . G 5 HOH 164 1214 164 HOH HOH A . G 5 HOH 165 1215 165 HOH HOH A . G 5 HOH 166 1216 166 HOH HOH A . G 5 HOH 167 1217 167 HOH HOH A . G 5 HOH 168 1218 168 HOH HOH A . G 5 HOH 169 1219 169 HOH HOH A . G 5 HOH 170 1220 170 HOH HOH A . G 5 HOH 171 1221 171 HOH HOH A . G 5 HOH 172 1222 172 HOH HOH A . G 5 HOH 173 1223 173 HOH HOH A . G 5 HOH 174 1224 174 HOH HOH A . G 5 HOH 175 1225 175 HOH HOH A . G 5 HOH 176 1226 176 HOH HOH A . G 5 HOH 177 1227 177 HOH HOH A . G 5 HOH 178 1228 178 HOH HOH A . G 5 HOH 179 1229 179 HOH HOH A . G 5 HOH 180 1230 180 HOH HOH A . G 5 HOH 181 1231 181 HOH HOH A . G 5 HOH 182 1232 182 HOH HOH A . G 5 HOH 183 1233 183 HOH HOH A . G 5 HOH 184 1234 184 HOH HOH A . G 5 HOH 185 1235 185 HOH HOH A . G 5 HOH 186 1236 186 HOH HOH A . G 5 HOH 187 1237 187 HOH HOH A . G 5 HOH 188 1238 188 HOH HOH A . G 5 HOH 189 1239 189 HOH HOH A . G 5 HOH 190 1240 190 HOH HOH A . G 5 HOH 191 1241 191 HOH HOH A . G 5 HOH 192 1242 192 HOH HOH A . G 5 HOH 193 1243 193 HOH HOH A . G 5 HOH 194 1244 194 HOH HOH A . G 5 HOH 195 1245 195 HOH HOH A . G 5 HOH 196 1246 196 HOH HOH A . G 5 HOH 197 1247 197 HOH HOH A . G 5 HOH 198 1248 198 HOH HOH A . G 5 HOH 199 1249 199 HOH HOH A . G 5 HOH 200 1250 200 HOH HOH A . G 5 HOH 201 1251 201 HOH HOH A . G 5 HOH 202 1252 202 HOH HOH A . G 5 HOH 203 1253 203 HOH HOH A . G 5 HOH 204 1254 204 HOH HOH A . G 5 HOH 205 1255 205 HOH HOH A . G 5 HOH 206 1256 206 HOH HOH A . G 5 HOH 207 1257 207 HOH HOH A . G 5 HOH 208 1258 208 HOH HOH A . G 5 HOH 209 1259 209 HOH HOH A . G 5 HOH 210 1260 210 HOH HOH A . G 5 HOH 211 1261 211 HOH HOH A . G 5 HOH 212 1262 212 HOH HOH A . G 5 HOH 213 1263 213 HOH HOH A . G 5 HOH 214 1264 214 HOH HOH A . G 5 HOH 215 1265 215 HOH HOH A . G 5 HOH 216 1266 216 HOH HOH A . G 5 HOH 217 1267 217 HOH HOH A . G 5 HOH 218 1268 218 HOH HOH A . G 5 HOH 219 1269 219 HOH HOH A . G 5 HOH 220 1270 220 HOH HOH A . G 5 HOH 221 1271 221 HOH HOH A . G 5 HOH 222 1272 222 HOH HOH A . G 5 HOH 223 1273 223 HOH HOH A . G 5 HOH 224 1274 224 HOH HOH A . G 5 HOH 225 1275 225 HOH HOH A . G 5 HOH 226 1276 226 HOH HOH A . G 5 HOH 227 1277 227 HOH HOH A . G 5 HOH 228 1278 228 HOH HOH A . G 5 HOH 229 1279 229 HOH HOH A . G 5 HOH 230 1280 230 HOH HOH A . G 5 HOH 231 1281 231 HOH HOH A . G 5 HOH 232 1282 232 HOH HOH A . G 5 HOH 233 1283 233 HOH HOH A . G 5 HOH 234 1284 234 HOH HOH A . G 5 HOH 235 1285 235 HOH HOH A . G 5 HOH 236 1286 236 HOH HOH A . G 5 HOH 237 1287 237 HOH HOH A . G 5 HOH 238 1288 238 HOH HOH A . G 5 HOH 239 1289 239 HOH HOH A . G 5 HOH 240 1290 240 HOH HOH A . G 5 HOH 241 1291 241 HOH HOH A . G 5 HOH 242 1292 242 HOH HOH A . G 5 HOH 243 1293 243 HOH HOH A . G 5 HOH 244 1294 244 HOH HOH A . G 5 HOH 245 1295 245 HOH HOH A . G 5 HOH 246 1296 246 HOH HOH A . G 5 HOH 247 1297 247 HOH HOH A . G 5 HOH 248 1298 248 HOH HOH A . G 5 HOH 249 1299 249 HOH HOH A . G 5 HOH 250 1300 250 HOH HOH A . G 5 HOH 251 1301 251 HOH HOH A . G 5 HOH 252 1302 252 HOH HOH A . G 5 HOH 253 1303 253 HOH HOH A . G 5 HOH 254 1304 254 HOH HOH A . G 5 HOH 255 1305 255 HOH HOH A . G 5 HOH 256 1306 256 HOH HOH A . G 5 HOH 257 1307 257 HOH HOH A . G 5 HOH 258 1308 258 HOH HOH A . G 5 HOH 259 1309 259 HOH HOH A . G 5 HOH 260 1310 260 HOH HOH A . G 5 HOH 261 1311 261 HOH HOH A . G 5 HOH 262 1312 262 HOH HOH A . G 5 HOH 263 1313 263 HOH HOH A . G 5 HOH 264 1314 264 HOH HOH A . G 5 HOH 265 1315 265 HOH HOH A . G 5 HOH 266 1316 266 HOH HOH A . G 5 HOH 267 1317 267 HOH HOH A . G 5 HOH 268 1318 268 HOH HOH A . G 5 HOH 269 1319 269 HOH HOH A . G 5 HOH 270 1320 270 HOH HOH A . G 5 HOH 271 1321 271 HOH HOH A . G 5 HOH 272 1322 272 HOH HOH A . G 5 HOH 273 1323 273 HOH HOH A . G 5 HOH 274 1324 274 HOH HOH A . G 5 HOH 275 1325 275 HOH HOH A . G 5 HOH 276 1326 276 HOH HOH A . G 5 HOH 277 1327 277 HOH HOH A . G 5 HOH 278 1328 278 HOH HOH A . G 5 HOH 279 1329 279 HOH HOH A . G 5 HOH 280 1330 280 HOH HOH A . G 5 HOH 281 1331 281 HOH HOH A . G 5 HOH 282 1332 282 HOH HOH A . G 5 HOH 283 1333 283 HOH HOH A . G 5 HOH 284 1334 284 HOH HOH A . G 5 HOH 285 1335 285 HOH HOH A . G 5 HOH 286 1336 286 HOH HOH A . G 5 HOH 287 1337 287 HOH HOH A . G 5 HOH 288 1338 288 HOH HOH A . G 5 HOH 289 1339 289 HOH HOH A . G 5 HOH 290 1340 290 HOH HOH A . G 5 HOH 291 1341 291 HOH HOH A . G 5 HOH 292 1342 292 HOH HOH A . G 5 HOH 293 1343 293 HOH HOH A . G 5 HOH 294 1344 294 HOH HOH A . G 5 HOH 295 1345 295 HOH HOH A . G 5 HOH 296 1346 296 HOH HOH A . G 5 HOH 297 1347 297 HOH HOH A . G 5 HOH 298 1348 298 HOH HOH A . G 5 HOH 299 1349 299 HOH HOH A . G 5 HOH 300 1350 300 HOH HOH A . G 5 HOH 301 1351 301 HOH HOH A . G 5 HOH 302 1352 302 HOH HOH A . G 5 HOH 303 1353 303 HOH HOH A . G 5 HOH 304 1354 304 HOH HOH A . G 5 HOH 305 1355 305 HOH HOH A . G 5 HOH 306 1356 306 HOH HOH A . G 5 HOH 307 1357 307 HOH HOH A . G 5 HOH 308 1358 308 HOH HOH A . G 5 HOH 309 1359 309 HOH HOH A . G 5 HOH 310 1360 310 HOH HOH A . G 5 HOH 311 1361 311 HOH HOH A . G 5 HOH 312 1362 312 HOH HOH A . G 5 HOH 313 1363 313 HOH HOH A . G 5 HOH 314 1364 314 HOH HOH A . G 5 HOH 315 1365 315 HOH HOH A . G 5 HOH 316 1366 316 HOH HOH A . G 5 HOH 317 1367 317 HOH HOH A . G 5 HOH 318 1368 318 HOH HOH A . G 5 HOH 319 1369 319 HOH HOH A . G 5 HOH 320 1370 320 HOH HOH A . G 5 HOH 321 1371 321 HOH HOH A . G 5 HOH 322 1372 322 HOH HOH A . G 5 HOH 323 1373 323 HOH HOH A . G 5 HOH 324 1374 324 HOH HOH A . G 5 HOH 325 1375 325 HOH HOH A . G 5 HOH 326 1376 326 HOH HOH A . G 5 HOH 327 1377 327 HOH HOH A . G 5 HOH 328 1378 328 HOH HOH A . G 5 HOH 329 1379 329 HOH HOH A . G 5 HOH 330 1380 330 HOH HOH A . G 5 HOH 331 1381 331 HOH HOH A . G 5 HOH 332 1382 332 HOH HOH A . G 5 HOH 333 1383 333 HOH HOH A . G 5 HOH 334 1384 334 HOH HOH A . G 5 HOH 335 1385 335 HOH HOH A . G 5 HOH 336 1386 336 HOH HOH A . G 5 HOH 337 1387 337 HOH HOH A . G 5 HOH 338 1388 338 HOH HOH A . G 5 HOH 339 1389 339 HOH HOH A . G 5 HOH 340 1390 340 HOH HOH A . G 5 HOH 341 1391 341 HOH HOH A . G 5 HOH 342 1392 342 HOH HOH A . G 5 HOH 343 1393 343 HOH HOH A . G 5 HOH 344 1394 344 HOH HOH A . G 5 HOH 345 1395 345 HOH HOH A . G 5 HOH 346 1396 346 HOH HOH A . G 5 HOH 347 1397 347 HOH HOH A . G 5 HOH 348 1398 348 HOH HOH A . G 5 HOH 349 1399 349 HOH HOH A . G 5 HOH 350 1400 350 HOH HOH A . G 5 HOH 351 1401 351 HOH HOH A . G 5 HOH 352 1402 352 HOH HOH A . G 5 HOH 353 1403 353 HOH HOH A . G 5 HOH 354 1404 354 HOH HOH A . G 5 HOH 355 1405 355 HOH HOH A . G 5 HOH 356 1406 356 HOH HOH A . G 5 HOH 357 1407 357 HOH HOH A . G 5 HOH 358 1408 358 HOH HOH A . G 5 HOH 359 1409 359 HOH HOH A . G 5 HOH 360 1410 360 HOH HOH A . G 5 HOH 361 1411 361 HOH HOH A . G 5 HOH 362 1412 362 HOH HOH A . G 5 HOH 363 1413 363 HOH HOH A . G 5 HOH 364 1414 364 HOH HOH A . G 5 HOH 365 1415 365 HOH HOH A . G 5 HOH 366 1416 366 HOH HOH A . G 5 HOH 367 1417 367 HOH HOH A . G 5 HOH 368 1418 368 HOH HOH A . G 5 HOH 369 1419 369 HOH HOH A . G 5 HOH 370 1420 370 HOH HOH A . G 5 HOH 371 1421 371 HOH HOH A . G 5 HOH 372 1422 372 HOH HOH A . G 5 HOH 373 1423 373 HOH HOH A . G 5 HOH 374 1424 374 HOH HOH A . G 5 HOH 375 1425 375 HOH HOH A . G 5 HOH 376 1426 376 HOH HOH A . G 5 HOH 377 1427 377 HOH HOH A . G 5 HOH 378 1428 378 HOH HOH A . G 5 HOH 379 1429 379 HOH HOH A . G 5 HOH 380 1430 380 HOH HOH A . G 5 HOH 381 1431 381 HOH HOH A . G 5 HOH 382 1432 382 HOH HOH A . G 5 HOH 383 1433 383 HOH HOH A . G 5 HOH 384 1434 384 HOH HOH A . G 5 HOH 385 1435 385 HOH HOH A . G 5 HOH 386 1436 386 HOH HOH A . G 5 HOH 387 1437 387 HOH HOH A . G 5 HOH 388 1438 388 HOH HOH A . G 5 HOH 389 1439 389 HOH HOH A . G 5 HOH 390 1440 390 HOH HOH A . G 5 HOH 391 1441 391 HOH HOH A . G 5 HOH 392 1442 392 HOH HOH A . G 5 HOH 393 1443 393 HOH HOH A . G 5 HOH 394 1444 394 HOH HOH A . G 5 HOH 395 1445 395 HOH HOH A . G 5 HOH 396 1446 396 HOH HOH A . G 5 HOH 397 1447 397 HOH HOH A . G 5 HOH 398 1448 398 HOH HOH A . G 5 HOH 399 1449 399 HOH HOH A . G 5 HOH 400 1450 400 HOH HOH A . G 5 HOH 401 1451 401 HOH HOH A . G 5 HOH 402 1452 402 HOH HOH A . G 5 HOH 403 1453 403 HOH HOH A . G 5 HOH 404 1454 404 HOH HOH A . G 5 HOH 405 1455 405 HOH HOH A . G 5 HOH 406 1456 406 HOH HOH A . G 5 HOH 407 1457 407 HOH HOH A . G 5 HOH 408 1458 408 HOH HOH A . G 5 HOH 409 1459 409 HOH HOH A . G 5 HOH 410 1460 410 HOH HOH A . G 5 HOH 411 1461 411 HOH HOH A . G 5 HOH 412 1462 412 HOH HOH A . G 5 HOH 413 1463 413 HOH HOH A . G 5 HOH 414 1464 414 HOH HOH A . G 5 HOH 415 1465 415 HOH HOH A . G 5 HOH 416 1466 416 HOH HOH A . G 5 HOH 417 1467 417 HOH HOH A . G 5 HOH 418 1468 418 HOH HOH A . G 5 HOH 419 1469 419 HOH HOH A . G 5 HOH 420 1470 420 HOH HOH A . G 5 HOH 421 1471 421 HOH HOH A . G 5 HOH 422 1472 422 HOH HOH A . G 5 HOH 423 1473 423 HOH HOH A . G 5 HOH 424 1474 424 HOH HOH A . G 5 HOH 425 1475 425 HOH HOH A . G 5 HOH 426 1476 426 HOH HOH A . G 5 HOH 427 1477 427 HOH HOH A . G 5 HOH 428 1478 428 HOH HOH A . G 5 HOH 429 1479 429 HOH HOH A . G 5 HOH 430 1480 430 HOH HOH A . G 5 HOH 431 1481 431 HOH HOH A . G 5 HOH 432 1482 432 HOH HOH A . G 5 HOH 433 1483 433 HOH HOH A . G 5 HOH 434 1484 434 HOH HOH A . G 5 HOH 435 1485 435 HOH HOH A . G 5 HOH 436 1486 436 HOH HOH A . G 5 HOH 437 1487 437 HOH HOH A . G 5 HOH 438 1488 438 HOH HOH A . G 5 HOH 439 1489 439 HOH HOH A . G 5 HOH 440 1490 440 HOH HOH A . G 5 HOH 441 1491 441 HOH HOH A . G 5 HOH 442 1492 442 HOH HOH A . G 5 HOH 443 1493 443 HOH HOH A . G 5 HOH 444 1494 444 HOH HOH A . G 5 HOH 445 1495 445 HOH HOH A . G 5 HOH 446 1496 446 HOH HOH A . G 5 HOH 447 1497 447 HOH HOH A . G 5 HOH 448 1498 448 HOH HOH A . G 5 HOH 449 1499 449 HOH HOH A . G 5 HOH 450 1500 450 HOH HOH A . G 5 HOH 451 1501 451 HOH HOH A . G 5 HOH 452 1502 452 HOH HOH A . G 5 HOH 453 1503 453 HOH HOH A . G 5 HOH 454 1504 454 HOH HOH A . G 5 HOH 455 1505 455 HOH HOH A . G 5 HOH 456 1506 456 HOH HOH A . G 5 HOH 457 1507 457 HOH HOH A . G 5 HOH 458 1508 458 HOH HOH A . G 5 HOH 459 1509 459 HOH HOH A . G 5 HOH 460 1510 460 HOH HOH A . G 5 HOH 461 1511 461 HOH HOH A . G 5 HOH 462 1512 462 HOH HOH A . G 5 HOH 463 1513 463 HOH HOH A . G 5 HOH 464 1514 464 HOH HOH A . G 5 HOH 465 1515 465 HOH HOH A . G 5 HOH 466 1516 466 HOH HOH A . G 5 HOH 467 1517 467 HOH HOH A . G 5 HOH 468 1518 468 HOH HOH A . G 5 HOH 469 1519 469 HOH HOH A . G 5 HOH 470 1520 470 HOH HOH A . G 5 HOH 471 1521 471 HOH HOH A . G 5 HOH 472 1522 472 HOH HOH A . G 5 HOH 473 1523 473 HOH HOH A . G 5 HOH 474 1524 474 HOH HOH A . G 5 HOH 475 1525 475 HOH HOH A . G 5 HOH 476 1526 476 HOH HOH A . G 5 HOH 477 1527 477 HOH HOH A . G 5 HOH 478 1528 478 HOH HOH A . G 5 HOH 479 1529 479 HOH HOH A . G 5 HOH 480 1530 480 HOH HOH A . G 5 HOH 481 1531 481 HOH HOH A . G 5 HOH 482 1532 482 HOH HOH A . G 5 HOH 483 1533 483 HOH HOH A . G 5 HOH 484 1534 484 HOH HOH A . G 5 HOH 485 1535 485 HOH HOH A . G 5 HOH 486 1536 486 HOH HOH A . G 5 HOH 487 1537 487 HOH HOH A . G 5 HOH 488 1538 488 HOH HOH A . G 5 HOH 489 1539 489 HOH HOH A . G 5 HOH 490 1540 490 HOH HOH A . G 5 HOH 491 1541 491 HOH HOH A . G 5 HOH 492 1542 492 HOH HOH A . G 5 HOH 493 1543 493 HOH HOH A . G 5 HOH 494 1544 494 HOH HOH A . G 5 HOH 495 1545 495 HOH HOH A . G 5 HOH 496 1546 496 HOH HOH A . G 5 HOH 497 1547 497 HOH HOH A . G 5 HOH 498 1548 498 HOH HOH A . G 5 HOH 499 1549 499 HOH HOH A . G 5 HOH 500 1550 500 HOH HOH A . G 5 HOH 501 1551 501 HOH HOH A . G 5 HOH 502 1552 502 HOH HOH A . G 5 HOH 503 1553 503 HOH HOH A . G 5 HOH 504 1554 504 HOH HOH A . G 5 HOH 505 1555 505 HOH HOH A . G 5 HOH 506 1556 506 HOH HOH A . G 5 HOH 507 1557 507 HOH HOH A . G 5 HOH 508 1558 508 HOH HOH A . G 5 HOH 509 1559 509 HOH HOH A . G 5 HOH 510 1560 510 HOH HOH A . G 5 HOH 511 1561 511 HOH HOH A . G 5 HOH 512 1562 512 HOH HOH A . G 5 HOH 513 1563 513 HOH HOH A . G 5 HOH 514 1564 514 HOH HOH A . G 5 HOH 515 1565 515 HOH HOH A . G 5 HOH 516 1566 516 HOH HOH A . G 5 HOH 517 1567 517 HOH HOH A . G 5 HOH 518 1568 518 HOH HOH A . G 5 HOH 519 1569 519 HOH HOH A . G 5 HOH 520 1570 520 HOH HOH A . G 5 HOH 521 1571 521 HOH HOH A . G 5 HOH 522 1572 522 HOH HOH A . G 5 HOH 523 1573 523 HOH HOH A . G 5 HOH 524 1574 524 HOH HOH A . G 5 HOH 525 1575 525 HOH HOH A . G 5 HOH 526 1576 526 HOH HOH A . G 5 HOH 527 1577 527 HOH HOH A . G 5 HOH 528 1578 528 HOH HOH A . G 5 HOH 529 1579 529 HOH HOH A . G 5 HOH 530 1580 530 HOH HOH A . G 5 HOH 531 1581 531 HOH HOH A . G 5 HOH 532 1582 532 HOH HOH A . G 5 HOH 533 1583 533 HOH HOH A . G 5 HOH 534 1584 534 HOH HOH A . G 5 HOH 535 1585 535 HOH HOH A . G 5 HOH 536 1586 536 HOH HOH A . G 5 HOH 537 1587 537 HOH HOH A . G 5 HOH 538 1588 538 HOH HOH A . G 5 HOH 539 1589 539 HOH HOH A . G 5 HOH 540 1590 540 HOH HOH A . G 5 HOH 541 1591 541 HOH HOH A . G 5 HOH 542 1592 542 HOH HOH A . G 5 HOH 543 1593 543 HOH HOH A . G 5 HOH 544 1594 544 HOH HOH A . G 5 HOH 545 1595 545 HOH HOH A . G 5 HOH 546 1596 546 HOH HOH A . G 5 HOH 547 1597 547 HOH HOH A . G 5 HOH 548 1598 548 HOH HOH A . G 5 HOH 549 1599 549 HOH HOH A . G 5 HOH 550 1600 550 HOH HOH A . G 5 HOH 551 1601 551 HOH HOH A . G 5 HOH 552 1602 552 HOH HOH A . G 5 HOH 553 1603 553 HOH HOH A . G 5 HOH 554 1604 554 HOH HOH A . G 5 HOH 555 1605 555 HOH HOH A . G 5 HOH 556 1606 556 HOH HOH A . G 5 HOH 557 1607 557 HOH HOH A . G 5 HOH 558 1608 558 HOH HOH A . G 5 HOH 559 1609 559 HOH HOH A . G 5 HOH 560 1610 560 HOH HOH A . G 5 HOH 561 1611 561 HOH HOH A . G 5 HOH 562 1612 562 HOH HOH A . G 5 HOH 563 1613 563 HOH HOH A . G 5 HOH 564 1614 564 HOH HOH A . G 5 HOH 565 1615 565 HOH HOH A . G 5 HOH 566 1616 566 HOH HOH A . G 5 HOH 567 1617 567 HOH HOH A . G 5 HOH 568 1618 568 HOH HOH A . G 5 HOH 569 1619 569 HOH HOH A . G 5 HOH 570 1620 570 HOH HOH A . G 5 HOH 571 1621 571 HOH HOH A . G 5 HOH 572 1622 572 HOH HOH A . G 5 HOH 573 1623 573 HOH HOH A . G 5 HOH 574 1624 574 HOH HOH A . G 5 HOH 575 1625 575 HOH HOH A . G 5 HOH 576 1626 576 HOH HOH A . G 5 HOH 577 1627 577 HOH HOH A . G 5 HOH 578 1628 578 HOH HOH A . G 5 HOH 579 1629 579 HOH HOH A . G 5 HOH 580 1630 580 HOH HOH A . G 5 HOH 581 1631 581 HOH HOH A . G 5 HOH 582 1632 582 HOH HOH A . G 5 HOH 583 1633 583 HOH HOH A . G 5 HOH 584 1634 584 HOH HOH A . G 5 HOH 585 1635 585 HOH HOH A . G 5 HOH 586 1636 586 HOH HOH A . G 5 HOH 587 1637 587 HOH HOH A . G 5 HOH 588 1638 588 HOH HOH A . G 5 HOH 589 1639 589 HOH HOH A . G 5 HOH 590 1640 590 HOH HOH A . G 5 HOH 591 1641 591 HOH HOH A . G 5 HOH 592 1642 592 HOH HOH A . G 5 HOH 593 1643 593 HOH HOH A . G 5 HOH 594 1644 594 HOH HOH A . G 5 HOH 595 1645 595 HOH HOH A . G 5 HOH 596 1646 596 HOH HOH A . G 5 HOH 597 1647 597 HOH HOH A . G 5 HOH 598 1648 598 HOH HOH A . G 5 HOH 599 1649 599 HOH HOH A . G 5 HOH 600 1650 600 HOH HOH A . G 5 HOH 601 1651 601 HOH HOH A . G 5 HOH 602 1652 602 HOH HOH A . G 5 HOH 603 1653 603 HOH HOH A . G 5 HOH 604 1654 604 HOH HOH A . G 5 HOH 605 1655 605 HOH HOH A . G 5 HOH 606 1656 606 HOH HOH A . G 5 HOH 607 1657 607 HOH HOH A . G 5 HOH 608 1658 608 HOH HOH A . G 5 HOH 609 1659 609 HOH HOH A . G 5 HOH 610 1660 610 HOH HOH A . G 5 HOH 611 1661 611 HOH HOH A . G 5 HOH 612 1662 612 HOH HOH A . G 5 HOH 613 1663 613 HOH HOH A . G 5 HOH 614 1664 614 HOH HOH A . G 5 HOH 615 1665 615 HOH HOH A . G 5 HOH 616 1666 616 HOH HOH A . G 5 HOH 617 1667 617 HOH HOH A . G 5 HOH 618 1668 618 HOH HOH A . G 5 HOH 619 1669 619 HOH HOH A . G 5 HOH 620 1670 620 HOH HOH A . G 5 HOH 621 1671 621 HOH HOH A . G 5 HOH 622 1672 622 HOH HOH A . G 5 HOH 623 1673 623 HOH HOH A . G 5 HOH 624 1674 624 HOH HOH A . G 5 HOH 625 1675 625 HOH HOH A . G 5 HOH 626 1676 626 HOH HOH A . G 5 HOH 627 1677 627 HOH HOH A . G 5 HOH 628 1678 628 HOH HOH A . G 5 HOH 629 1679 629 HOH HOH A . G 5 HOH 630 1680 630 HOH HOH A . G 5 HOH 631 1681 631 HOH HOH A . G 5 HOH 632 1682 632 HOH HOH A . G 5 HOH 633 1683 633 HOH HOH A . G 5 HOH 634 1684 634 HOH HOH A . G 5 HOH 635 1685 635 HOH HOH A . G 5 HOH 636 1686 636 HOH HOH A . G 5 HOH 637 1687 637 HOH HOH A . G 5 HOH 638 1688 638 HOH HOH A . G 5 HOH 639 1689 639 HOH HOH A . G 5 HOH 640 1690 640 HOH HOH A . G 5 HOH 641 1691 641 HOH HOH A . G 5 HOH 642 1692 642 HOH HOH A . G 5 HOH 643 1693 643 HOH HOH A . G 5 HOH 644 1694 644 HOH HOH A . G 5 HOH 645 1695 645 HOH HOH A . G 5 HOH 646 1696 646 HOH HOH A . G 5 HOH 647 1697 647 HOH HOH A . G 5 HOH 648 1698 648 HOH HOH A . G 5 HOH 649 1699 649 HOH HOH A . G 5 HOH 650 1700 650 HOH HOH A . G 5 HOH 651 1701 651 HOH HOH A . G 5 HOH 652 1702 652 HOH HOH A . G 5 HOH 653 1703 653 HOH HOH A . G 5 HOH 654 1704 654 HOH HOH A . G 5 HOH 655 1705 655 HOH HOH A . G 5 HOH 656 1706 656 HOH HOH A . G 5 HOH 657 1707 657 HOH HOH A . G 5 HOH 658 1708 658 HOH HOH A . G 5 HOH 659 1709 659 HOH HOH A . G 5 HOH 660 1710 660 HOH HOH A . G 5 HOH 661 1711 661 HOH HOH A . G 5 HOH 662 1712 662 HOH HOH A . G 5 HOH 663 1713 663 HOH HOH A . G 5 HOH 664 1714 664 HOH HOH A . G 5 HOH 665 1715 665 HOH HOH A . G 5 HOH 666 1716 666 HOH HOH A . G 5 HOH 667 1717 667 HOH HOH A . G 5 HOH 668 1718 668 HOH HOH A . G 5 HOH 669 1719 669 HOH HOH A . G 5 HOH 670 1720 670 HOH HOH A . G 5 HOH 671 1721 671 HOH HOH A . G 5 HOH 672 1722 672 HOH HOH A . G 5 HOH 673 1723 673 HOH HOH A . G 5 HOH 674 1724 674 HOH HOH A . G 5 HOH 675 1725 675 HOH HOH A . G 5 HOH 676 1726 676 HOH HOH A . G 5 HOH 677 1727 677 HOH HOH A . G 5 HOH 678 1728 678 HOH HOH A . G 5 HOH 679 1729 679 HOH HOH A . G 5 HOH 680 1730 680 HOH HOH A . G 5 HOH 681 1731 681 HOH HOH A . G 5 HOH 682 1732 682 HOH HOH A . G 5 HOH 683 1733 683 HOH HOH A . G 5 HOH 684 1734 684 HOH HOH A . G 5 HOH 685 1735 685 HOH HOH A . G 5 HOH 686 1736 686 HOH HOH A . G 5 HOH 687 1737 687 HOH HOH A . G 5 HOH 688 1738 688 HOH HOH A . G 5 HOH 689 1739 689 HOH HOH A . G 5 HOH 690 1740 690 HOH HOH A . G 5 HOH 691 1741 691 HOH HOH A . G 5 HOH 692 1742 692 HOH HOH A . G 5 HOH 693 1743 693 HOH HOH A . G 5 HOH 694 1744 694 HOH HOH A . G 5 HOH 695 1745 695 HOH HOH A . G 5 HOH 696 1746 696 HOH HOH A . G 5 HOH 697 1747 697 HOH HOH A . G 5 HOH 698 1748 698 HOH HOH A . G 5 HOH 699 1749 699 HOH HOH A . G 5 HOH 700 1750 700 HOH HOH A . G 5 HOH 701 1751 701 HOH HOH A . G 5 HOH 702 1752 702 HOH HOH A . G 5 HOH 703 1753 703 HOH HOH A . G 5 HOH 704 1754 704 HOH HOH A . G 5 HOH 705 1755 705 HOH HOH A . G 5 HOH 706 1756 706 HOH HOH A . G 5 HOH 707 1757 707 HOH HOH A . G 5 HOH 708 1758 708 HOH HOH A . G 5 HOH 709 1759 709 HOH HOH A . G 5 HOH 710 1760 710 HOH HOH A . G 5 HOH 711 1761 711 HOH HOH A . G 5 HOH 712 1762 712 HOH HOH A . G 5 HOH 713 1763 713 HOH HOH A . G 5 HOH 714 1764 714 HOH HOH A . G 5 HOH 715 1765 715 HOH HOH A . G 5 HOH 716 1766 716 HOH HOH A . G 5 HOH 717 1767 717 HOH HOH A . G 5 HOH 718 1768 718 HOH HOH A . G 5 HOH 719 1769 719 HOH HOH A . G 5 HOH 720 1770 720 HOH HOH A . G 5 HOH 721 1771 721 HOH HOH A . G 5 HOH 722 1772 722 HOH HOH A . G 5 HOH 723 1773 723 HOH HOH A . G 5 HOH 724 1774 724 HOH HOH A . G 5 HOH 725 1775 725 HOH HOH A . G 5 HOH 726 1776 726 HOH HOH A . G 5 HOH 727 1777 727 HOH HOH A . G 5 HOH 728 1778 728 HOH HOH A . G 5 HOH 729 1779 729 HOH HOH A . G 5 HOH 730 1780 730 HOH HOH A . G 5 HOH 731 1781 731 HOH HOH A . G 5 HOH 732 1782 732 HOH HOH A . G 5 HOH 733 1783 733 HOH HOH A . G 5 HOH 734 1784 734 HOH HOH A . G 5 HOH 735 1785 735 HOH HOH A . G 5 HOH 736 1786 736 HOH HOH A . G 5 HOH 737 1787 737 HOH HOH A . G 5 HOH 738 1788 738 HOH HOH A . G 5 HOH 739 1789 739 HOH HOH A . G 5 HOH 740 1790 740 HOH HOH A . G 5 HOH 741 1791 741 HOH HOH A . G 5 HOH 742 1792 742 HOH HOH A . G 5 HOH 743 1793 743 HOH HOH A . G 5 HOH 744 1794 744 HOH HOH A . G 5 HOH 745 1795 745 HOH HOH A . G 5 HOH 746 1796 746 HOH HOH A . G 5 HOH 747 1797 747 HOH HOH A . G 5 HOH 748 1798 748 HOH HOH A . G 5 HOH 749 1799 749 HOH HOH A . G 5 HOH 750 1800 750 HOH HOH A . G 5 HOH 751 1801 751 HOH HOH A . G 5 HOH 752 1802 752 HOH HOH A . G 5 HOH 753 1803 753 HOH HOH A . G 5 HOH 754 1804 754 HOH HOH A . G 5 HOH 755 1805 755 HOH HOH A . G 5 HOH 756 1806 756 HOH HOH A . G 5 HOH 757 1807 757 HOH HOH A . G 5 HOH 758 1808 758 HOH HOH A . G 5 HOH 759 1809 759 HOH HOH A . G 5 HOH 760 1810 760 HOH HOH A . G 5 HOH 761 1811 761 HOH HOH A . G 5 HOH 762 1812 762 HOH HOH A . G 5 HOH 763 1813 763 HOH HOH A . G 5 HOH 764 1814 764 HOH HOH A . G 5 HOH 765 1815 765 HOH HOH A . G 5 HOH 766 1816 766 HOH HOH A . G 5 HOH 767 1817 767 HOH HOH A . G 5 HOH 768 1818 768 HOH HOH A . G 5 HOH 769 1819 769 HOH HOH A . G 5 HOH 770 1820 770 HOH HOH A . G 5 HOH 771 1821 771 HOH HOH A . G 5 HOH 772 1822 772 HOH HOH A . G 5 HOH 773 1823 773 HOH HOH A . G 5 HOH 774 1824 774 HOH HOH A . G 5 HOH 775 1825 775 HOH HOH A . G 5 HOH 776 1826 776 HOH HOH A . G 5 HOH 777 1827 777 HOH HOH A . G 5 HOH 778 1828 778 HOH HOH A . G 5 HOH 779 1829 779 HOH HOH A . G 5 HOH 780 1830 780 HOH HOH A . G 5 HOH 781 1831 781 HOH HOH A . G 5 HOH 782 1832 782 HOH HOH A . G 5 HOH 783 1833 783 HOH HOH A . G 5 HOH 784 1834 784 HOH HOH A . G 5 HOH 785 1835 785 HOH HOH A . G 5 HOH 786 1836 786 HOH HOH A . G 5 HOH 787 1837 787 HOH HOH A . G 5 HOH 788 1838 788 HOH HOH A . G 5 HOH 789 1839 789 HOH HOH A . G 5 HOH 790 1840 790 HOH HOH A . G 5 HOH 791 1841 791 HOH HOH A . G 5 HOH 792 1842 792 HOH HOH A . G 5 HOH 793 1843 793 HOH HOH A . G 5 HOH 794 1844 794 HOH HOH A . G 5 HOH 795 1845 795 HOH HOH A . G 5 HOH 796 1846 796 HOH HOH A . G 5 HOH 797 1847 797 HOH HOH A . G 5 HOH 798 1848 798 HOH HOH A . G 5 HOH 799 1849 799 HOH HOH A . G 5 HOH 800 1850 800 HOH HOH A . G 5 HOH 801 1851 801 HOH HOH A . G 5 HOH 802 1852 802 HOH HOH A . G 5 HOH 803 1853 803 HOH HOH A . G 5 HOH 804 1854 804 HOH HOH A . G 5 HOH 805 1855 805 HOH HOH A . G 5 HOH 806 1856 806 HOH HOH A . G 5 HOH 807 1857 807 HOH HOH A . G 5 HOH 808 1858 808 HOH HOH A . G 5 HOH 809 1859 809 HOH HOH A . G 5 HOH 810 1860 810 HOH HOH A . G 5 HOH 811 1861 811 HOH HOH A . G 5 HOH 812 1862 812 HOH HOH A . G 5 HOH 813 1863 813 HOH HOH A . G 5 HOH 814 1864 814 HOH HOH A . G 5 HOH 815 1865 815 HOH HOH A . G 5 HOH 816 1866 816 HOH HOH A . G 5 HOH 817 1867 817 HOH HOH A . G 5 HOH 818 1868 818 HOH HOH A . G 5 HOH 819 1869 819 HOH HOH A . G 5 HOH 820 1870 820 HOH HOH A . G 5 HOH 821 1871 821 HOH HOH A . G 5 HOH 822 1872 822 HOH HOH A . G 5 HOH 823 1873 823 HOH HOH A . G 5 HOH 824 1874 824 HOH HOH A . G 5 HOH 825 1875 825 HOH HOH A . G 5 HOH 826 1876 826 HOH HOH A . G 5 HOH 827 1877 827 HOH HOH A . G 5 HOH 828 1878 828 HOH HOH A . G 5 HOH 829 1879 829 HOH HOH A . G 5 HOH 830 1880 830 HOH HOH A . G 5 HOH 831 1881 831 HOH HOH A . G 5 HOH 832 1882 832 HOH HOH A . G 5 HOH 833 1883 833 HOH HOH A . G 5 HOH 834 1884 834 HOH HOH A . G 5 HOH 835 1885 835 HOH HOH A . G 5 HOH 836 1886 836 HOH HOH A . G 5 HOH 837 1887 837 HOH HOH A . G 5 HOH 838 1888 838 HOH HOH A . G 5 HOH 839 1889 839 HOH HOH A . G 5 HOH 840 1890 840 HOH HOH A . G 5 HOH 841 1891 841 HOH HOH A . G 5 HOH 842 1892 842 HOH HOH A . G 5 HOH 843 1893 843 HOH HOH A . G 5 HOH 844 1894 844 HOH HOH A . G 5 HOH 845 1895 845 HOH HOH A . G 5 HOH 846 1896 846 HOH HOH A . G 5 HOH 847 1897 847 HOH HOH A . G 5 HOH 848 1898 848 HOH HOH A . G 5 HOH 849 1899 849 HOH HOH A . G 5 HOH 850 1900 850 HOH HOH A . G 5 HOH 851 1901 851 HOH HOH A . G 5 HOH 852 1902 852 HOH HOH A . G 5 HOH 853 1903 853 HOH HOH A . G 5 HOH 854 1904 854 HOH HOH A . G 5 HOH 855 1905 855 HOH HOH A . G 5 HOH 856 1906 856 HOH HOH A . G 5 HOH 857 1907 857 HOH HOH A . G 5 HOH 858 1908 858 HOH HOH A . G 5 HOH 859 1909 859 HOH HOH A . G 5 HOH 860 1910 860 HOH HOH A . G 5 HOH 861 1911 861 HOH HOH A . G 5 HOH 862 1912 862 HOH HOH A . G 5 HOH 863 1913 863 HOH HOH A . G 5 HOH 864 1914 864 HOH HOH A . G 5 HOH 865 1915 865 HOH HOH A . G 5 HOH 866 1916 866 HOH HOH A . G 5 HOH 867 1917 867 HOH HOH A . G 5 HOH 868 1918 868 HOH HOH A . G 5 HOH 869 1919 869 HOH HOH A . G 5 HOH 870 1920 870 HOH HOH A . G 5 HOH 871 1921 871 HOH HOH A . G 5 HOH 872 1922 872 HOH HOH A . G 5 HOH 873 1923 873 HOH HOH A . G 5 HOH 874 1924 874 HOH HOH A . G 5 HOH 875 1925 875 HOH HOH A . G 5 HOH 876 1926 876 HOH HOH A . G 5 HOH 877 1927 877 HOH HOH A . G 5 HOH 878 1928 878 HOH HOH A . G 5 HOH 879 1929 879 HOH HOH A . G 5 HOH 880 1930 880 HOH HOH A . G 5 HOH 881 1931 881 HOH HOH A . G 5 HOH 882 1932 882 HOH HOH A . G 5 HOH 883 1933 883 HOH HOH A . G 5 HOH 884 1934 884 HOH HOH A . G 5 HOH 885 1935 885 HOH HOH A . G 5 HOH 886 1936 886 HOH HOH A . G 5 HOH 887 1937 887 HOH HOH A . G 5 HOH 888 1938 888 HOH HOH A . G 5 HOH 889 1939 889 HOH HOH A . G 5 HOH 890 1940 890 HOH HOH A . G 5 HOH 891 1941 891 HOH HOH A . G 5 HOH 892 1942 892 HOH HOH A . G 5 HOH 893 1943 893 HOH HOH A . G 5 HOH 894 1944 894 HOH HOH A . G 5 HOH 895 1945 895 HOH HOH A . G 5 HOH 896 1946 896 HOH HOH A . G 5 HOH 897 1947 897 HOH HOH A . G 5 HOH 898 1948 898 HOH HOH A . G 5 HOH 899 1949 899 HOH HOH A . G 5 HOH 900 1950 900 HOH HOH A . G 5 HOH 901 1951 901 HOH HOH A . G 5 HOH 902 1952 902 HOH HOH A . G 5 HOH 903 1953 903 HOH HOH A . G 5 HOH 904 1954 904 HOH HOH A . G 5 HOH 905 1955 905 HOH HOH A . G 5 HOH 906 1956 906 HOH HOH A . G 5 HOH 907 1957 907 HOH HOH A . G 5 HOH 908 1958 908 HOH HOH A . G 5 HOH 909 1959 909 HOH HOH A . G 5 HOH 910 1960 910 HOH HOH A . G 5 HOH 911 1961 911 HOH HOH A . G 5 HOH 912 1962 912 HOH HOH A . G 5 HOH 913 1963 913 HOH HOH A . G 5 HOH 914 1964 914 HOH HOH A . G 5 HOH 915 1965 915 HOH HOH A . G 5 HOH 916 1966 916 HOH HOH A . G 5 HOH 917 1967 917 HOH HOH A . G 5 HOH 918 1968 918 HOH HOH A . G 5 HOH 919 1969 919 HOH HOH A . G 5 HOH 920 1970 920 HOH HOH A . G 5 HOH 921 1971 921 HOH HOH A . G 5 HOH 922 1972 922 HOH HOH A . G 5 HOH 923 1973 923 HOH HOH A . G 5 HOH 924 1974 924 HOH HOH A . G 5 HOH 925 1975 925 HOH HOH A . G 5 HOH 926 1976 926 HOH HOH A . G 5 HOH 927 1977 927 HOH HOH A . G 5 HOH 928 1978 928 HOH HOH A . G 5 HOH 929 1979 929 HOH HOH A . G 5 HOH 930 1980 930 HOH HOH A . G 5 HOH 931 1981 931 HOH HOH A . G 5 HOH 932 1982 932 HOH HOH A . G 5 HOH 933 1983 933 HOH HOH A . G 5 HOH 934 1984 934 HOH HOH A . G 5 HOH 935 1985 935 HOH HOH A . G 5 HOH 936 1986 936 HOH HOH A . G 5 HOH 937 1987 937 HOH HOH A . G 5 HOH 938 1988 938 HOH HOH A . G 5 HOH 939 1989 939 HOH HOH A . G 5 HOH 940 1990 940 HOH HOH A . G 5 HOH 941 1991 941 HOH HOH A . G 5 HOH 942 1992 942 HOH HOH A . G 5 HOH 943 1993 943 HOH HOH A . G 5 HOH 944 1994 944 HOH HOH A . G 5 HOH 945 1995 945 HOH HOH A . G 5 HOH 946 1996 946 HOH HOH A . G 5 HOH 947 1997 947 HOH HOH A . G 5 HOH 948 1998 948 HOH HOH A . G 5 HOH 949 1999 949 HOH HOH A . G 5 HOH 950 2000 950 HOH HOH A . G 5 HOH 951 2001 951 HOH HOH A . G 5 HOH 952 2002 952 HOH HOH A . G 5 HOH 953 2003 953 HOH HOH A . G 5 HOH 954 2004 954 HOH HOH A . G 5 HOH 955 2005 955 HOH HOH A . G 5 HOH 956 2006 956 HOH HOH A . G 5 HOH 957 2007 957 HOH HOH A . G 5 HOH 958 2008 958 HOH HOH A . G 5 HOH 959 2009 959 HOH HOH A . G 5 HOH 960 2010 960 HOH HOH A . G 5 HOH 961 2011 961 HOH HOH A . G 5 HOH 962 2012 962 HOH HOH A . G 5 HOH 963 2013 963 HOH HOH A . G 5 HOH 964 2014 964 HOH HOH A . G 5 HOH 965 2015 965 HOH HOH A . G 5 HOH 966 2016 966 HOH HOH A . G 5 HOH 967 2017 967 HOH HOH A . G 5 HOH 968 2018 968 HOH HOH A . G 5 HOH 969 2019 969 HOH HOH A . G 5 HOH 970 2020 970 HOH HOH A . G 5 HOH 971 2021 971 HOH HOH A . G 5 HOH 972 2022 972 HOH HOH A . G 5 HOH 973 2023 973 HOH HOH A . G 5 HOH 974 2024 974 HOH HOH A . G 5 HOH 975 2025 975 HOH HOH A . G 5 HOH 976 2026 976 HOH HOH A . G 5 HOH 977 2027 977 HOH HOH A . G 5 HOH 978 2028 978 HOH HOH A . G 5 HOH 979 2029 979 HOH HOH A . G 5 HOH 980 2030 980 HOH HOH A . G 5 HOH 981 2031 981 HOH HOH A . G 5 HOH 982 2032 982 HOH HOH A . G 5 HOH 983 2033 983 HOH HOH A . G 5 HOH 984 2034 984 HOH HOH A . G 5 HOH 985 2035 985 HOH HOH A . G 5 HOH 986 2036 986 HOH HOH A . G 5 HOH 987 2037 987 HOH HOH A . G 5 HOH 988 2038 988 HOH HOH A . G 5 HOH 989 2039 989 HOH HOH A . G 5 HOH 990 2040 990 HOH HOH A . G 5 HOH 991 2041 991 HOH HOH A . G 5 HOH 992 2042 992 HOH HOH A . G 5 HOH 993 2043 993 HOH HOH A . G 5 HOH 994 2044 994 HOH HOH A . G 5 HOH 995 2045 995 HOH HOH A . G 5 HOH 996 2046 996 HOH HOH A . G 5 HOH 997 2047 997 HOH HOH A . G 5 HOH 998 2048 998 HOH HOH A . G 5 HOH 999 2049 999 HOH HOH A . G 5 HOH 1000 2050 1000 HOH HOH A . G 5 HOH 1001 2051 1001 HOH HOH A . G 5 HOH 1002 2052 1002 HOH HOH A . G 5 HOH 1003 2053 1003 HOH HOH A . G 5 HOH 1004 2054 1004 HOH HOH A . G 5 HOH 1005 2055 1005 HOH HOH A . G 5 HOH 1006 2056 1006 HOH HOH A . G 5 HOH 1007 2057 1007 HOH HOH A . G 5 HOH 1008 2058 1008 HOH HOH A . G 5 HOH 1009 2059 1009 HOH HOH A . G 5 HOH 1010 2060 1010 HOH HOH A . G 5 HOH 1011 2061 1011 HOH HOH A . G 5 HOH 1012 2062 1012 HOH HOH A . G 5 HOH 1013 2063 1013 HOH HOH A . G 5 HOH 1014 2064 1014 HOH HOH A . G 5 HOH 1015 2065 1015 HOH HOH A . G 5 HOH 1016 2066 1016 HOH HOH A . G 5 HOH 1017 2067 1017 HOH HOH A . G 5 HOH 1018 2068 1018 HOH HOH A . G 5 HOH 1019 2069 1019 HOH HOH A . G 5 HOH 1020 2070 1020 HOH HOH A . G 5 HOH 1021 2071 1021 HOH HOH A . G 5 HOH 1022 2072 1022 HOH HOH A . G 5 HOH 1023 2073 1023 HOH HOH A . G 5 HOH 1024 2074 1024 HOH HOH A . G 5 HOH 1025 2075 1025 HOH HOH A . G 5 HOH 1026 2076 1026 HOH HOH A . G 5 HOH 1027 2077 1027 HOH HOH A . G 5 HOH 1028 2078 1028 HOH HOH A . G 5 HOH 1029 2079 1029 HOH HOH A . G 5 HOH 1030 2080 1030 HOH HOH A . G 5 HOH 1031 2081 1031 HOH HOH A . G 5 HOH 1032 2082 1032 HOH HOH A . G 5 HOH 1033 2083 1033 HOH HOH A . G 5 HOH 1034 2084 1034 HOH HOH A . G 5 HOH 1035 2085 1035 HOH HOH A . G 5 HOH 1036 2086 1036 HOH HOH A . G 5 HOH 1037 2087 1037 HOH HOH A . G 5 HOH 1038 2088 1038 HOH HOH A . G 5 HOH 1039 2089 1039 HOH HOH A . G 5 HOH 1040 2090 1040 HOH HOH A . G 5 HOH 1041 2091 1041 HOH HOH A . G 5 HOH 1042 2092 1042 HOH HOH A . G 5 HOH 1043 2093 1043 HOH HOH A . G 5 HOH 1044 2094 1044 HOH HOH A . G 5 HOH 1045 2095 1045 HOH HOH A . G 5 HOH 1046 2096 1046 HOH HOH A . G 5 HOH 1047 2097 1047 HOH HOH A . G 5 HOH 1048 2098 1048 HOH HOH A . G 5 HOH 1049 2099 1049 HOH HOH A . G 5 HOH 1050 2100 1050 HOH HOH A . G 5 HOH 1051 2101 1051 HOH HOH A . G 5 HOH 1052 2102 1052 HOH HOH A . G 5 HOH 1053 2103 1053 HOH HOH A . G 5 HOH 1054 2104 1054 HOH HOH A . G 5 HOH 1055 2105 1055 HOH HOH A . G 5 HOH 1056 2106 1056 HOH HOH A . G 5 HOH 1057 2107 1057 HOH HOH A . G 5 HOH 1058 2108 1058 HOH HOH A . G 5 HOH 1059 2109 1059 HOH HOH A . G 5 HOH 1060 2110 1060 HOH HOH A . G 5 HOH 1061 2111 1061 HOH HOH A . G 5 HOH 1062 2112 1062 HOH HOH A . G 5 HOH 1063 2113 1063 HOH HOH A . G 5 HOH 1064 2114 1064 HOH HOH A . G 5 HOH 1065 2115 1065 HOH HOH A . G 5 HOH 1066 2116 1066 HOH HOH A . G 5 HOH 1067 2117 1067 HOH HOH A . G 5 HOH 1068 2118 1068 HOH HOH A . G 5 HOH 1069 2119 1069 HOH HOH A . G 5 HOH 1070 2120 1070 HOH HOH A . G 5 HOH 1071 2121 1071 HOH HOH A . G 5 HOH 1072 2122 1072 HOH HOH A . G 5 HOH 1073 2123 1073 HOH HOH A . G 5 HOH 1074 2124 1074 HOH HOH A . G 5 HOH 1075 2125 1075 HOH HOH A . G 5 HOH 1076 2126 1076 HOH HOH A . G 5 HOH 1077 2127 1077 HOH HOH A . G 5 HOH 1078 2128 1078 HOH HOH A . G 5 HOH 1079 2129 1079 HOH HOH A . G 5 HOH 1080 2130 1080 HOH HOH A . G 5 HOH 1081 2131 1081 HOH HOH A . G 5 HOH 1082 2132 1082 HOH HOH A . G 5 HOH 1083 2133 1083 HOH HOH A . G 5 HOH 1084 2134 1084 HOH HOH A . G 5 HOH 1085 2135 1085 HOH HOH A . G 5 HOH 1086 2136 1086 HOH HOH A . G 5 HOH 1087 2137 1087 HOH HOH A . G 5 HOH 1088 2138 1088 HOH HOH A . G 5 HOH 1089 2139 1089 HOH HOH A . G 5 HOH 1090 2140 1090 HOH HOH A . G 5 HOH 1091 2141 1091 HOH HOH A . G 5 HOH 1092 2142 1092 HOH HOH A . G 5 HOH 1093 2143 1093 HOH HOH A . G 5 HOH 1094 2144 1094 HOH HOH A . G 5 HOH 1095 2145 1095 HOH HOH A . G 5 HOH 1096 2146 1096 HOH HOH A . G 5 HOH 1097 2147 1097 HOH HOH A . G 5 HOH 1098 2148 1098 HOH HOH A . G 5 HOH 1099 2149 1099 HOH HOH A . G 5 HOH 1100 2150 1100 HOH HOH A . G 5 HOH 1101 2151 1101 HOH HOH A . G 5 HOH 1102 2152 1102 HOH HOH A . G 5 HOH 1103 2153 1103 HOH HOH A . G 5 HOH 1104 2154 1104 HOH HOH A . G 5 HOH 1105 2155 1105 HOH HOH A . G 5 HOH 1106 2156 1106 HOH HOH A . G 5 HOH 1107 2157 1107 HOH HOH A . G 5 HOH 1108 2158 1108 HOH HOH A . G 5 HOH 1109 2159 1109 HOH HOH A . G 5 HOH 1110 2160 1110 HOH HOH A . G 5 HOH 1111 2161 1111 HOH HOH A . G 5 HOH 1112 2162 1112 HOH HOH A . G 5 HOH 1113 2163 1113 HOH HOH A . G 5 HOH 1114 2164 1114 HOH HOH A . G 5 HOH 1115 2165 1115 HOH HOH A . G 5 HOH 1116 2166 1116 HOH HOH A . G 5 HOH 1117 2167 1117 HOH HOH A . G 5 HOH 1118 2168 1118 HOH HOH A . G 5 HOH 1119 2169 1119 HOH HOH A . G 5 HOH 1120 2170 1120 HOH HOH A . G 5 HOH 1121 2171 1121 HOH HOH A . G 5 HOH 1122 2172 1122 HOH HOH A . G 5 HOH 1123 2173 1123 HOH HOH A . G 5 HOH 1124 2174 1124 HOH HOH A . G 5 HOH 1125 2175 1125 HOH HOH A . G 5 HOH 1126 2176 1126 HOH HOH A . G 5 HOH 1127 2177 1127 HOH HOH A . G 5 HOH 1128 2178 1128 HOH HOH A . G 5 HOH 1129 2179 1129 HOH HOH A . G 5 HOH 1130 2180 1130 HOH HOH A . G 5 HOH 1131 2181 1131 HOH HOH A . G 5 HOH 1132 2182 1132 HOH HOH A . G 5 HOH 1133 2183 1133 HOH HOH A . G 5 HOH 1134 2184 1134 HOH HOH A . G 5 HOH 1135 2185 1135 HOH HOH A . G 5 HOH 1136 2186 1136 HOH HOH A . G 5 HOH 1137 2187 1137 HOH HOH A . G 5 HOH 1138 2188 1138 HOH HOH A . G 5 HOH 1139 2189 1139 HOH HOH A . G 5 HOH 1140 2190 1140 HOH HOH A . G 5 HOH 1141 2191 1141 HOH HOH A . G 5 HOH 1142 2192 1142 HOH HOH A . G 5 HOH 1143 2193 1143 HOH HOH A . G 5 HOH 1144 2194 1144 HOH HOH A . G 5 HOH 1145 2195 1145 HOH HOH A . G 5 HOH 1146 2196 1146 HOH HOH A . G 5 HOH 1147 2197 1147 HOH HOH A . G 5 HOH 1148 2198 1148 HOH HOH A . G 5 HOH 1149 2199 1149 HOH HOH A . G 5 HOH 1150 2200 1150 HOH HOH A . G 5 HOH 1151 2201 1151 HOH HOH A . G 5 HOH 1152 2202 1152 HOH HOH A . G 5 HOH 1153 2203 1153 HOH HOH A . G 5 HOH 1154 2204 1154 HOH HOH A . G 5 HOH 1155 2205 1155 HOH HOH A . G 5 HOH 1156 2206 1156 HOH HOH A . G 5 HOH 1157 2207 1157 HOH HOH A . G 5 HOH 1158 2208 1158 HOH HOH A . G 5 HOH 1159 2209 1159 HOH HOH A . G 5 HOH 1160 2210 1160 HOH HOH A . G 5 HOH 1161 2211 1161 HOH HOH A . G 5 HOH 1162 2212 1162 HOH HOH A . G 5 HOH 1163 2213 1163 HOH HOH A . G 5 HOH 1164 2214 1164 HOH HOH A . G 5 HOH 1165 2215 1165 HOH HOH A . G 5 HOH 1166 2216 1166 HOH HOH A . G 5 HOH 1167 2217 1167 HOH HOH A . G 5 HOH 1168 2218 1168 HOH HOH A . G 5 HOH 1169 2219 1169 HOH HOH A . G 5 HOH 1170 2220 1170 HOH HOH A . G 5 HOH 1171 2221 1171 HOH HOH A . G 5 HOH 1172 2222 1172 HOH HOH A . G 5 HOH 1173 2223 1173 HOH HOH A . G 5 HOH 1174 2224 1174 HOH HOH A . G 5 HOH 1175 2225 1175 HOH HOH A . G 5 HOH 1176 2226 1176 HOH HOH A . G 5 HOH 1177 2227 1177 HOH HOH A . G 5 HOH 1178 2228 1178 HOH HOH A . G 5 HOH 1179 2229 1179 HOH HOH A . G 5 HOH 1180 2230 1180 HOH HOH A . G 5 HOH 1181 2231 1181 HOH HOH A . G 5 HOH 1182 2232 1182 HOH HOH A . G 5 HOH 1183 2233 1183 HOH HOH A . G 5 HOH 1184 2234 1184 HOH HOH A . G 5 HOH 1185 2235 1185 HOH HOH A . G 5 HOH 1186 2236 1186 HOH HOH A . G 5 HOH 1187 2237 1187 HOH HOH A . G 5 HOH 1188 2238 1188 HOH HOH A . G 5 HOH 1189 2239 1189 HOH HOH A . G 5 HOH 1190 2240 1190 HOH HOH A . G 5 HOH 1191 2241 1191 HOH HOH A . G 5 HOH 1192 2242 1192 HOH HOH A . G 5 HOH 1193 2243 1193 HOH HOH A . G 5 HOH 1194 2244 1194 HOH HOH A . G 5 HOH 1195 2245 1195 HOH HOH A . G 5 HOH 1196 2246 1196 HOH HOH A . G 5 HOH 1197 2247 1197 HOH HOH A . G 5 HOH 1198 2248 1198 HOH HOH A . G 5 HOH 1199 2249 1199 HOH HOH A . G 5 HOH 1200 2250 1200 HOH HOH A . G 5 HOH 1201 2251 1201 HOH HOH A . G 5 HOH 1202 2252 1202 HOH HOH A . G 5 HOH 1203 2253 1203 HOH HOH A . G 5 HOH 1204 2254 1204 HOH HOH A . G 5 HOH 1205 2255 1205 HOH HOH A . G 5 HOH 1206 2256 1206 HOH HOH A . G 5 HOH 1207 2257 1207 HOH HOH A . G 5 HOH 1208 2258 1208 HOH HOH A . G 5 HOH 1209 2259 1209 HOH HOH A . G 5 HOH 1210 2260 1210 HOH HOH A . G 5 HOH 1211 2261 1211 HOH HOH A . G 5 HOH 1212 2262 1212 HOH HOH A . G 5 HOH 1213 2263 1213 HOH HOH A . G 5 HOH 1214 2264 1214 HOH HOH A . G 5 HOH 1215 2265 1215 HOH HOH A . G 5 HOH 1216 2266 1216 HOH HOH A . G 5 HOH 1217 2267 1217 HOH HOH A . G 5 HOH 1218 2268 1218 HOH HOH A . G 5 HOH 1219 2269 1219 HOH HOH A . G 5 HOH 1220 2270 1220 HOH HOH A . G 5 HOH 1221 2271 1221 HOH HOH A . G 5 HOH 1222 2272 1222 HOH HOH A . G 5 HOH 1223 2273 1223 HOH HOH A . G 5 HOH 1224 2274 1224 HOH HOH A . G 5 HOH 1225 2275 1225 HOH HOH A . G 5 HOH 1226 2276 1226 HOH HOH A . G 5 HOH 1227 2277 1227 HOH HOH A . G 5 HOH 1228 2278 1228 HOH HOH A . G 5 HOH 1229 2279 1229 HOH HOH A . G 5 HOH 1230 2280 1230 HOH HOH A . G 5 HOH 1231 2281 1231 HOH HOH A . G 5 HOH 1232 2282 1232 HOH HOH A . G 5 HOH 1233 2283 1233 HOH HOH A . G 5 HOH 1234 2284 1234 HOH HOH A . G 5 HOH 1235 2285 1235 HOH HOH A . G 5 HOH 1236 2286 1236 HOH HOH A . G 5 HOH 1237 2287 1237 HOH HOH A . G 5 HOH 1238 2288 1238 HOH HOH A . G 5 HOH 1239 2289 1239 HOH HOH A . G 5 HOH 1240 2290 1240 HOH HOH A . G 5 HOH 1241 2291 1241 HOH HOH A . G 5 HOH 1242 2292 1242 HOH HOH A . G 5 HOH 1243 2293 1243 HOH HOH A . G 5 HOH 1244 2294 1244 HOH HOH A . G 5 HOH 1245 2295 1245 HOH HOH A . G 5 HOH 1246 2296 1246 HOH HOH A . G 5 HOH 1247 2297 1247 HOH HOH A . G 5 HOH 1248 2298 1248 HOH HOH A . G 5 HOH 1249 2299 1249 HOH HOH A . G 5 HOH 1250 2300 1250 HOH HOH A . G 5 HOH 1251 2301 1251 HOH HOH A . G 5 HOH 1252 2302 1252 HOH HOH A . G 5 HOH 1253 2303 1253 HOH HOH A . G 5 HOH 1254 2304 1254 HOH HOH A . G 5 HOH 1255 2305 1255 HOH HOH A . G 5 HOH 1256 2306 1256 HOH HOH A . G 5 HOH 1257 2307 1257 HOH HOH A . G 5 HOH 1258 2308 1258 HOH HOH A . G 5 HOH 1259 2309 1259 HOH HOH A . G 5 HOH 1260 2310 1260 HOH HOH A . G 5 HOH 1261 2311 1261 HOH HOH A . G 5 HOH 1262 2312 1262 HOH HOH A . G 5 HOH 1263 2313 1263 HOH HOH A . G 5 HOH 1264 2314 1264 HOH HOH A . G 5 HOH 1265 2315 1265 HOH HOH A . G 5 HOH 1266 2316 1266 HOH HOH A . G 5 HOH 1267 2317 1267 HOH HOH A . G 5 HOH 1268 2318 1268 HOH HOH A . G 5 HOH 1269 2319 1269 HOH HOH A . G 5 HOH 1270 2320 1270 HOH HOH A . G 5 HOH 1271 2321 1271 HOH HOH A . G 5 HOH 1272 2322 1272 HOH HOH A . G 5 HOH 1273 2323 1273 HOH HOH A . G 5 HOH 1274 2324 1274 HOH HOH A . G 5 HOH 1275 2325 1275 HOH HOH A . G 5 HOH 1276 2326 1276 HOH HOH A . G 5 HOH 1277 2327 1277 HOH HOH A . G 5 HOH 1278 2328 1278 HOH HOH A . G 5 HOH 1279 2329 1279 HOH HOH A . G 5 HOH 1280 2330 1280 HOH HOH A . G 5 HOH 1281 2331 1281 HOH HOH A . G 5 HOH 1282 2332 1282 HOH HOH A . G 5 HOH 1283 2333 1283 HOH HOH A . G 5 HOH 1284 2334 1284 HOH HOH A . G 5 HOH 1285 2335 1285 HOH HOH A . G 5 HOH 1286 2336 1286 HOH HOH A . G 5 HOH 1287 2337 1287 HOH HOH A . G 5 HOH 1288 2338 1288 HOH HOH A . G 5 HOH 1289 2339 1289 HOH HOH A . G 5 HOH 1290 2340 1290 HOH HOH A . G 5 HOH 1291 2341 1291 HOH HOH A . G 5 HOH 1292 2342 1292 HOH HOH A . G 5 HOH 1293 2343 1293 HOH HOH A . G 5 HOH 1294 2344 1294 HOH HOH A . G 5 HOH 1295 2345 1295 HOH HOH A . G 5 HOH 1296 2346 1296 HOH HOH A . G 5 HOH 1297 2347 1297 HOH HOH A . G 5 HOH 1298 2348 1298 HOH HOH A . G 5 HOH 1299 2349 1299 HOH HOH A . G 5 HOH 1300 2350 1300 HOH HOH A . G 5 HOH 1301 2351 1301 HOH HOH A . G 5 HOH 1302 2352 1302 HOH HOH A . G 5 HOH 1303 2353 1303 HOH HOH A . G 5 HOH 1304 2354 1304 HOH HOH A . G 5 HOH 1305 2355 1305 HOH HOH A . G 5 HOH 1306 2356 1306 HOH HOH A . G 5 HOH 1307 2357 1307 HOH HOH A . G 5 HOH 1308 2358 1308 HOH HOH A . G 5 HOH 1309 2359 1309 HOH HOH A . G 5 HOH 1310 2360 1310 HOH HOH A . G 5 HOH 1311 2361 1311 HOH HOH A . G 5 HOH 1312 2362 1312 HOH HOH A . G 5 HOH 1313 2363 1313 HOH HOH A . G 5 HOH 1314 2364 1314 HOH HOH A . G 5 HOH 1315 2365 1315 HOH HOH A . G 5 HOH 1316 2366 1316 HOH HOH A . G 5 HOH 1317 2367 1317 HOH HOH A . G 5 HOH 1318 2368 1318 HOH HOH A . G 5 HOH 1319 2369 1319 HOH HOH A . G 5 HOH 1320 2370 1320 HOH HOH A . G 5 HOH 1321 2371 1321 HOH HOH A . G 5 HOH 1322 2372 1322 HOH HOH A . G 5 HOH 1323 2373 1323 HOH HOH A . G 5 HOH 1324 2374 1324 HOH HOH A . G 5 HOH 1325 2375 1325 HOH HOH A . G 5 HOH 1326 2376 1326 HOH HOH A . G 5 HOH 1327 2377 1327 HOH HOH A . G 5 HOH 1328 2378 1328 HOH HOH A . G 5 HOH 1329 2379 1329 HOH HOH A . G 5 HOH 1330 2380 1330 HOH HOH A . G 5 HOH 1331 2381 1331 HOH HOH A . G 5 HOH 1332 2382 1332 HOH HOH A . G 5 HOH 1333 2383 1333 HOH HOH A . G 5 HOH 1334 2384 1334 HOH HOH A . G 5 HOH 1335 2385 1335 HOH HOH A . G 5 HOH 1336 2386 1336 HOH HOH A . G 5 HOH 1337 2387 1337 HOH HOH A . G 5 HOH 1338 2388 1338 HOH HOH A . G 5 HOH 1339 2389 1339 HOH HOH A . G 5 HOH 1340 2390 1340 HOH HOH A . G 5 HOH 1341 2391 1341 HOH HOH A . G 5 HOH 1342 2392 1342 HOH HOH A . G 5 HOH 1343 2393 1343 HOH HOH A . G 5 HOH 1344 2394 1344 HOH HOH A . G 5 HOH 1345 2395 1345 HOH HOH A . G 5 HOH 1346 2396 1346 HOH HOH A . G 5 HOH 1347 2397 1347 HOH HOH A . G 5 HOH 1348 2398 1348 HOH HOH A . G 5 HOH 1349 2399 1349 HOH HOH A . G 5 HOH 1350 2400 1350 HOH HOH A . G 5 HOH 1351 2401 1351 HOH HOH A . G 5 HOH 1352 2402 1352 HOH HOH A . G 5 HOH 1353 2403 1353 HOH HOH A . G 5 HOH 1354 2404 1354 HOH HOH A . G 5 HOH 1355 2405 1355 HOH HOH A . G 5 HOH 1356 2406 1356 HOH HOH A . G 5 HOH 1357 2407 1357 HOH HOH A . G 5 HOH 1358 2408 1358 HOH HOH A . G 5 HOH 1359 2409 1359 HOH HOH A . G 5 HOH 1360 2410 1360 HOH HOH A . G 5 HOH 1361 2411 1361 HOH HOH A . G 5 HOH 1362 2412 1362 HOH HOH A . G 5 HOH 1363 2413 1363 HOH HOH A . G 5 HOH 1364 2414 1364 HOH HOH A . G 5 HOH 1365 2415 1365 HOH HOH A . G 5 HOH 1366 2416 1366 HOH HOH A . G 5 HOH 1367 2417 1367 HOH HOH A . G 5 HOH 1368 2418 1368 HOH HOH A . G 5 HOH 1369 2419 1369 HOH HOH A . G 5 HOH 1370 2420 1370 HOH HOH A . G 5 HOH 1371 2421 1371 HOH HOH A . G 5 HOH 1372 2422 1372 HOH HOH A . G 5 HOH 1373 2423 1373 HOH HOH A . G 5 HOH 1374 2424 1374 HOH HOH A . G 5 HOH 1375 2425 1375 HOH HOH A . G 5 HOH 1376 2426 1376 HOH HOH A . G 5 HOH 1377 2427 1377 HOH HOH A . G 5 HOH 1378 2428 1378 HOH HOH A . G 5 HOH 1379 2429 1379 HOH HOH A . G 5 HOH 1380 2430 1380 HOH HOH A . G 5 HOH 1381 2431 1381 HOH HOH A . G 5 HOH 1382 2432 1382 HOH HOH A . G 5 HOH 1383 2433 1383 HOH HOH A . G 5 HOH 1384 2434 1384 HOH HOH A . G 5 HOH 1385 2435 1385 HOH HOH A . G 5 HOH 1386 2436 1386 HOH HOH A . G 5 HOH 1387 2437 1387 HOH HOH A . G 5 HOH 1388 2438 1388 HOH HOH A . G 5 HOH 1389 2439 1389 HOH HOH A . G 5 HOH 1390 2440 1390 HOH HOH A . G 5 HOH 1391 2441 1391 HOH HOH A . G 5 HOH 1392 2442 1392 HOH HOH A . G 5 HOH 1393 2443 1393 HOH HOH A . G 5 HOH 1394 2444 1394 HOH HOH A . G 5 HOH 1395 2445 1395 HOH HOH A . G 5 HOH 1396 2446 1396 HOH HOH A . G 5 HOH 1397 2447 1397 HOH HOH A . G 5 HOH 1398 2448 1398 HOH HOH A . G 5 HOH 1399 2449 1399 HOH HOH A . G 5 HOH 1400 2450 1400 HOH HOH A . G 5 HOH 1401 2451 1401 HOH HOH A . G 5 HOH 1402 2452 1402 HOH HOH A . G 5 HOH 1403 2453 1403 HOH HOH A . G 5 HOH 1404 2454 1404 HOH HOH A . G 5 HOH 1405 2455 1405 HOH HOH A . G 5 HOH 1406 2456 1406 HOH HOH A . G 5 HOH 1407 2457 1407 HOH HOH A . G 5 HOH 1408 2458 1408 HOH HOH A . G 5 HOH 1409 2459 1409 HOH HOH A . G 5 HOH 1410 2460 1410 HOH HOH A . G 5 HOH 1411 2461 1411 HOH HOH A . G 5 HOH 1412 2462 1412 HOH HOH A . G 5 HOH 1413 2463 1413 HOH HOH A . G 5 HOH 1414 2464 1414 HOH HOH A . G 5 HOH 1415 2465 1415 HOH HOH A . G 5 HOH 1416 2466 1416 HOH HOH A . G 5 HOH 1417 2467 1417 HOH HOH A . G 5 HOH 1418 2468 1418 HOH HOH A . G 5 HOH 1419 2469 1419 HOH HOH A . G 5 HOH 1420 2470 1420 HOH HOH A . G 5 HOH 1421 2471 1421 HOH HOH A . G 5 HOH 1422 2472 1422 HOH HOH A . G 5 HOH 1423 2473 1423 HOH HOH A . G 5 HOH 1424 2474 1424 HOH HOH A . G 5 HOH 1425 2475 1425 HOH HOH A . G 5 HOH 1426 2476 1426 HOH HOH A . G 5 HOH 1427 2477 1427 HOH HOH A . G 5 HOH 1428 2478 1428 HOH HOH A . G 5 HOH 1429 2479 1429 HOH HOH A . G 5 HOH 1430 2480 1430 HOH HOH A . G 5 HOH 1431 2481 1431 HOH HOH A . G 5 HOH 1432 2482 1432 HOH HOH A . G 5 HOH 1433 2483 1433 HOH HOH A . G 5 HOH 1434 2484 1434 HOH HOH A . G 5 HOH 1435 2485 1435 HOH HOH A . G 5 HOH 1436 2486 1436 HOH HOH A . G 5 HOH 1437 2487 1437 HOH HOH A . G 5 HOH 1438 2488 1438 HOH HOH A . G 5 HOH 1439 2489 1439 HOH HOH A . G 5 HOH 1440 2490 1440 HOH HOH A . G 5 HOH 1441 2491 1441 HOH HOH A . G 5 HOH 1442 2492 1442 HOH HOH A . G 5 HOH 1443 2493 1443 HOH HOH A . G 5 HOH 1444 2494 1444 HOH HOH A . G 5 HOH 1445 2495 1445 HOH HOH A . G 5 HOH 1446 2496 1446 HOH HOH A . G 5 HOH 1447 2497 1447 HOH HOH A . G 5 HOH 1448 2498 1448 HOH HOH A . G 5 HOH 1449 2499 1449 HOH HOH A . G 5 HOH 1450 2500 1450 HOH HOH A . G 5 HOH 1451 2501 1451 HOH HOH A . G 5 HOH 1452 2502 1452 HOH HOH A . G 5 HOH 1453 2503 1453 HOH HOH A . G 5 HOH 1454 2504 1454 HOH HOH A . G 5 HOH 1455 2505 1455 HOH HOH A . G 5 HOH 1456 2506 1456 HOH HOH A . G 5 HOH 1457 2507 1457 HOH HOH A . G 5 HOH 1458 2508 1458 HOH HOH A . G 5 HOH 1459 2509 1459 HOH HOH A . G 5 HOH 1460 2510 1460 HOH HOH A . G 5 HOH 1461 2511 1461 HOH HOH A . G 5 HOH 1462 2512 1462 HOH HOH A . G 5 HOH 1463 2513 1463 HOH HOH A . G 5 HOH 1464 2514 1464 HOH HOH A . G 5 HOH 1465 2515 1465 HOH HOH A . G 5 HOH 1466 2516 1466 HOH HOH A . G 5 HOH 1467 2517 1467 HOH HOH A . G 5 HOH 1468 2518 1468 HOH HOH A . G 5 HOH 1469 2519 1469 HOH HOH A . G 5 HOH 1470 2520 1470 HOH HOH A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2008-07-01 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-10-25 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' 3 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal SAINT . ? package ? ? 'data scaling' http://www.bruker-axs.de/index.html ? ? 1 REFMAC . ? program 'Murshudov, G.N.' ccp4@dl.ac.uk refinement http://www.ccp4.ac.uk/main.html Fortran_77 ? 2 PDB_EXTRACT 3.004 'September 10, 2007' package PDB sw-help@rcsb.rutgers.edu 'data extraction' http://pdb.rutgers.edu/software/ C++ ? 3 ADSC Quantum ? ? ? ? 'data collection' ? ? ? 4 DENZO . ? ? ? ? 'data reduction' ? ? ? 5 SCALEPACK . ? ? ? ? 'data scaling' ? ? ? 6 SADABS . ? ? ? ? 'data scaling' ? ? ? 7 CNS . ? ? ? ? phasing ? ? ? 8 # _pdbx_entry_details.sequence_details 'E970K CONFLICT IN UNP ENTRY Q24451' _pdbx_entry_details.entry_id 3BUB _pdbx_entry_details.compound_details ? _pdbx_entry_details.source_details ? _pdbx_entry_details.nonpolymer_details ? # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 TRP A 95 ? ? -169.85 -82.65 2 1 ASP A 106 ? ? -137.43 -62.33 3 1 ASP A 106 ? ? -122.89 -62.33 4 1 THR A 162 ? ? 68.02 -64.89 5 1 GLN A 227 ? ? -137.01 -44.91 6 1 ASP A 340 ? ? -175.05 -173.95 7 1 LYS A 345 ? A -86.19 -76.60 8 1 SER A 411 ? ? 43.78 -128.23 9 1 SER A 411 ? ? 50.43 -132.13 10 1 ILE A 549 ? ? -144.51 -48.79 11 1 LEU A 550 ? ? -170.75 112.93 12 1 PRO A 562 ? ? -83.15 41.08 13 1 PHE A 577 ? ? -100.81 74.77 14 1 ASN A 732 ? ? -91.41 59.88 15 1 SER A 762 ? ? 74.06 -6.19 16 1 ILE A 831 ? ? -118.26 76.05 17 1 SER A 833 ? A -158.61 -9.89 18 1 SER A 833 ? B -147.54 -26.51 19 1 ASP A 839 ? ? -127.91 -162.07 20 1 GLU A 991 ? ? 16.34 80.18 21 1 GLU A 992 ? ? -105.20 -102.77 22 1 HIS A 993 ? ? -32.88 107.25 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C5 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id A _pdbx_validate_chiral.auth_comp_id NAG _pdbx_validate_chiral.auth_seq_id 1046 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 5 water HOH #