data_3BLB # _entry.id 3BLB # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 3BLB RCSB RCSB045661 WWPDB D_1000045661 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1HTY 'dGMII + Tris' unspecified PDB 1HWW 'dGMII + Swainsonine, 1.87 Angstrom' unspecified PDB 1HXK 'dGMII + Deoxymannojirimicin' unspecified PDB 1PS2 'dGMII + Kifunensine' unspecified PDB 1QWN 'dGMII + 5fluoro-Gulosylfluoride' unspecified PDB 1QX1 'dGMII + 2F-mannosylF' unspecified PDB 1R33 'dGMII + 5-thio-D-mannopyranosylamine' unspecified PDB 1R34 'dGMII + 5-thio-D-mannopyranosylamidinium salt' unspecified PDB 1TQS 'dGMII + Salacinol' unspecified PDB 1TQT 'dGMII + Diastereomer of Salacinol' unspecified PDB 1TQU 'dGMII + Ghavamiol' unspecified PDB 1TQV 'dGMII + Blintol' unspecified PDB 1TQW 'dGMII + Blintol Diastereomer' unspecified PDB 2ALW 'dGMII + Noeuromycin' unspecified PDB 2F18 'dGMII + (2R,3R,4S)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' unspecified PDB 2F1A 'dGMII + (2R,3R,4S)-2-({[(1S)-2-hydroxy-1-phenylethyl]amino}methyl)pyrrolidine-3,4-diol' unspecified PDB 2F1B 'dGMII + (2R,3R,4S,5R)-2-({[(1R)-2-hydroxy-1-phenylethyl]amino}methyl)-5-methylpyrrolidine-3,4-diol' unspecified PDB 2F7O 'dGMII + Mannostatin A' unspecified PDB 2F7P 'dGMII + Benzyl-mannostatin A' unspecified PDB 2F7Q 'dGMII + Aminocyclopentitetrol' unspecified PDB 2F7R 'dGMII + Benzyl-aminocyclopentitetrol' unspecified # _pdbx_database_status.entry_id 3BLB _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2007-12-10 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Kuntz, D.A.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title 'Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom.' _citation.journal_abbrev 'To Be Published' _citation.journal_volume ? _citation.page_first ? _citation.page_last ? _citation.year ? _citation.journal_id_ASTM ? _citation.country ? _citation.journal_id_ISSN ? _citation.journal_id_CSD 0353 _citation.book_publisher ? _citation.pdbx_database_id_PubMed ? _citation.pdbx_database_id_DOI ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Kuntz, D.A.' 1 primary 'Rose, D.R.' 2 # _cell.length_a 68.767 _cell.length_b 109.662 _cell.length_c 138.900 _cell.angle_alpha 90.000 _cell.angle_beta 90.000 _cell.angle_gamma 90.000 _cell.entry_id 3BLB _cell.pdbx_unique_axis ? _cell.Z_PDB 4 _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.entry_id 3BLB _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.Int_Tables_number 19 _symmetry.cell_setting ? _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Alpha-mannosidase 2' 119701.617 1 3.2.1.114 ? 'Catalytic domain: Residues 76-1108' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 4 non-polymer syn 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL 173.210 1 ? ? ? ? 5 non-polymer syn '(4R)-2-METHYLPENTANE-2,4-DIOL' 118.174 1 ? ? ? ? 6 water nat water 18.015 1068 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Alpha-mannosidase II, Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase, MAN II, Golgi alpha-mannosidase II, AMAN II' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ASP n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASP n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'fruit fly' _entity_src_gen.gene_src_genus Drosophila _entity_src_gen.pdbx_gene_src_gene 'alpha-Man-II, GmII, CG18802' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain Berkeley _entity_src_gen.gene_src_tissue Head _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 7227 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fruit fly' _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus Drosophila _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMTBIP_NHIS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MAN2_DROME _struct_ref.pdbx_db_accession Q24451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;DDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHND PGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEAN SHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWD NKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTN VLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTLSGDFFTYADRSD NYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQE ALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFY VSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLL RKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPN GPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQ FIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIY RLVLEKVNNCVRPSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVSVMRRLTKSSAKT QRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS ; _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 3BLB _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q24451 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 3BLB ARG A 1 ? UNP Q24451 ? ? 'EXPRESSION TAG' 1 1 1 3BLB SER A 2 ? UNP Q24451 ? ? 'EXPRESSION TAG' 2 2 1 3BLB SER A 3 ? UNP Q24451 ? ? 'EXPRESSION TAG' 3 3 1 3BLB HIS A 4 ? UNP Q24451 ? ? 'EXPRESSION TAG' 4 4 1 3BLB HIS A 5 ? UNP Q24451 ? ? 'EXPRESSION TAG' 5 5 1 3BLB HIS A 6 ? UNP Q24451 ? ? 'EXPRESSION TAG' 6 6 1 3BLB HIS A 7 ? UNP Q24451 ? ? 'EXPRESSION TAG' 7 7 1 3BLB HIS A 8 ? UNP Q24451 ? ? 'EXPRESSION TAG' 8 8 1 3BLB HIS A 9 ? UNP Q24451 ? ? 'EXPRESSION TAG' 9 9 1 3BLB GLY A 10 ? UNP Q24451 ? ? 'EXPRESSION TAG' 10 10 1 3BLB GLU A 11 ? UNP Q24451 ? ? 'EXPRESSION TAG' 11 11 1 3BLB PHE A 12 ? UNP Q24451 ? ? 'EXPRESSION TAG' 12 12 1 3BLB LYS A 907 ? UNP Q24451 GLU 970 CONFLICT 907 13 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MRD non-polymer . '(4R)-2-METHYLPENTANE-2,4-DIOL' ? 'C6 H14 O2' 118.174 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SWA non-polymer . 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL SWAINSONINE 'C8 H15 N O3' 173.210 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.crystals_number 1 _exptl.entry_id 3BLB _exptl.method 'X-RAY DIFFRACTION' # _exptl_crystal.id 1 _exptl_crystal.density_Matthews 2.16 _exptl_crystal.density_meas ? _exptl_crystal.density_percent_sol 43.07 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 7.0 _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_details 'Tris-HCl, PEG 6000, MPD, NaCl, pH 7.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2002-03-21 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.97400 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE F1' _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline F1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.97400 # _reflns.entry_id 3BLB _reflns.B_iso_Wilson_estimate 11.900 _reflns.observed_criterion_sigma_F 0 _reflns.observed_criterion_sigma_I 0 _reflns.d_resolution_high 1.30 _reflns.d_resolution_low 30 _reflns.number_all 254722 _reflns.number_obs 254722 _reflns.percent_possible_obs 99.3 _reflns.pdbx_Rmerge_I_obs 0.112 _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI 14.04 _reflns.pdbx_redundancy 5.94 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.30 _reflns_shell.d_res_low 1.32 _reflns_shell.percent_possible_obs ? _reflns_shell.percent_possible_all 98.4 _reflns_shell.Rmerge_I_obs 0.654 _reflns_shell.meanI_over_sigI_obs 2.34 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.pdbx_redundancy 4 _reflns_shell.number_unique_all 13861 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 3BLB _refine.ls_d_res_high 1.300 _refine.ls_d_res_low 29.830 _refine.pdbx_data_cutoff_high_absF 261670.734 _refine.pdbx_data_cutoff_low_absF 0.000 _refine.ls_percent_reflns_obs 95.700 _refine.ls_number_reflns_obs 246212 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.ls_R_factor_R_work 0.166 _refine.ls_R_factor_R_free 0.185 _refine.ls_percent_reflns_R_free 4.800 _refine.ls_number_reflns_R_free 11766 _refine.ls_R_factor_R_free_error 0.002 _refine.B_iso_mean 14.100 _refine.solvent_model_param_bsol 57.908 _refine.solvent_model_param_ksol 0.380 _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.aniso_B[1][1] -1.990 _refine.aniso_B[2][2] 0.180 _refine.aniso_B[3][3] 1.820 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.solvent_model_details 'FLAT MODEL' _refine.overall_FOM_work_R_set 0.900 _refine.pdbx_ls_sigma_F 0 _refine.pdbx_ls_sigma_I ? _refine.ls_number_reflns_all 246212 _refine.ls_R_factor_all 0.168 _refine.ls_R_factor_obs 0.168 _refine.ls_redundancy_reflns_obs ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 'PDB entry 1HWW' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.occupancy_max ? _refine.occupancy_min ? _refine.details ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_overall_ESU_R ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.pdbx_overall_phase_error ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 3BLB _refine_analyze.Luzzati_coordinate_error_obs 0.120 _refine_analyze.Luzzati_sigma_a_obs 0.110 _refine_analyze.Luzzati_d_res_low_obs 30.000 _refine_analyze.Luzzati_coordinate_error_free 0.140 _refine_analyze.Luzzati_sigma_a_free 0.120 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8181 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 35 _refine_hist.number_atoms_solvent 1068 _refine_hist.number_atoms_total 9284 _refine_hist.d_res_high 1.300 _refine_hist.d_res_low 29.830 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d ? 0.019 ? ? 'X-RAY DIFFRACTION' ? c_angle_deg ? 1.950 ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d ? 25.400 ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d ? 1.430 ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it ? 1.520 1.500 ? 'X-RAY DIFFRACTION' ? c_mcangle_it ? 2.130 2.000 ? 'X-RAY DIFFRACTION' ? c_scbond_it ? 3.040 2.000 ? 'X-RAY DIFFRACTION' ? c_scangle_it ? 4.200 2.500 ? 'X-RAY DIFFRACTION' ? # loop_ _refine_ls_shell.d_res_high _refine_ls_shell.d_res_low _refine_ls_shell.pdbx_total_number_of_bins_used _refine_ls_shell.percent_reflns_obs _refine_ls_shell.number_reflns_R_work _refine_ls_shell.R_factor_all _refine_ls_shell.R_factor_R_work _refine_ls_shell.R_factor_R_free _refine_ls_shell.percent_reflns_R_free _refine_ls_shell.number_reflns_R_free _refine_ls_shell.R_factor_R_free_error _refine_ls_shell.number_reflns_all _refine_ls_shell.number_reflns_obs _refine_ls_shell.redundancy_reflns_obs _refine_ls_shell.pdbx_refine_id 1.300 1.310 50 . 3672 . 0.260 0.285 . 207 . . 3879 . 'X-RAY DIFFRACTION' 1.310 1.320 50 . 4341 . 0.251 0.288 . 207 . . 4548 . 'X-RAY DIFFRACTION' 1.320 1.330 50 . 4313 . 0.241 0.241 . 206 . . 4519 . 'X-RAY DIFFRACTION' 1.330 1.340 50 . 4416 . 0.240 0.255 . 208 . . 4624 . 'X-RAY DIFFRACTION' 1.340 1.350 50 . 4380 . 0.225 0.243 . 238 . . 4618 . 'X-RAY DIFFRACTION' 1.350 1.360 50 . 4429 . 0.234 0.255 . 217 . . 4646 . 'X-RAY DIFFRACTION' 1.360 1.370 50 . 4432 . 0.223 0.252 . 222 . . 4654 . 'X-RAY DIFFRACTION' 1.370 1.380 50 . 4470 . 0.220 0.232 . 232 . . 4702 . 'X-RAY DIFFRACTION' 1.380 1.390 50 . 4471 . 0.207 0.269 . 229 . . 4700 . 'X-RAY DIFFRACTION' 1.390 1.400 50 . 4455 . 0.205 0.214 . 218 . . 4673 . 'X-RAY DIFFRACTION' 1.400 1.410 50 . 4510 . 0.201 0.212 . 240 . . 4750 . 'X-RAY DIFFRACTION' 1.410 1.420 50 . 4573 . 0.198 0.212 . 229 . . 4802 . 'X-RAY DIFFRACTION' 1.420 1.440 50 . 4560 . 0.192 0.212 . 239 . . 4799 . 'X-RAY DIFFRACTION' 1.440 1.450 50 . 4518 . 0.188 0.188 . 231 . . 4749 . 'X-RAY DIFFRACTION' 1.450 1.460 50 . 4585 . 0.190 0.229 . 238 . . 4823 . 'X-RAY DIFFRACTION' 1.460 1.480 50 . 4553 . 0.177 0.206 . 263 . . 4816 . 'X-RAY DIFFRACTION' 1.480 1.490 50 . 4651 . 0.175 0.204 . 238 . . 4889 . 'X-RAY DIFFRACTION' 1.490 1.510 50 . 4608 . 0.172 0.207 . 226 . . 4834 . 'X-RAY DIFFRACTION' 1.510 1.520 50 . 4648 . 0.174 0.204 . 234 . . 4882 . 'X-RAY DIFFRACTION' 1.520 1.540 50 . 4651 . 0.170 0.204 . 256 . . 4907 . 'X-RAY DIFFRACTION' 1.540 1.560 50 . 4660 . 0.167 0.201 . 239 . . 4899 . 'X-RAY DIFFRACTION' 1.560 1.580 50 . 4680 . 0.162 0.196 . 242 . . 4922 . 'X-RAY DIFFRACTION' 1.580 1.600 50 . 4700 . 0.157 0.192 . 259 . . 4959 . 'X-RAY DIFFRACTION' 1.600 1.620 50 . 4758 . 0.154 0.186 . 138 . . 4896 . 'X-RAY DIFFRACTION' 1.620 1.640 50 . 4854 . 0.153 0.169 . 144 . . 4998 . 'X-RAY DIFFRACTION' 1.640 1.660 50 . 4736 . 0.154 0.189 . 162 . . 4898 . 'X-RAY DIFFRACTION' 1.660 1.680 50 . 4769 . 0.151 0.177 . 213 . . 4982 . 'X-RAY DIFFRACTION' 1.680 1.710 50 . 4774 . 0.154 0.189 . 188 . . 4962 . 'X-RAY DIFFRACTION' 1.710 1.740 50 . 4731 . 0.146 0.160 . 209 . . 4940 . 'X-RAY DIFFRACTION' 1.740 1.760 50 . 4797 . 0.144 0.165 . 214 . . 5011 . 'X-RAY DIFFRACTION' 1.760 1.790 50 . 4768 . 0.146 0.174 . 223 . . 4991 . 'X-RAY DIFFRACTION' 1.790 1.830 50 . 4783 . 0.147 0.171 . 254 . . 5037 . 'X-RAY DIFFRACTION' 1.830 1.860 50 . 4771 . 0.150 0.181 . 253 . . 5024 . 'X-RAY DIFFRACTION' 1.860 1.900 50 . 4801 . 0.148 0.170 . 256 . . 5057 . 'X-RAY DIFFRACTION' 1.900 1.940 50 . 4759 . 0.148 0.166 . 249 . . 5008 . 'X-RAY DIFFRACTION' 1.940 1.990 50 . 4835 . 0.154 0.165 . 253 . . 5088 . 'X-RAY DIFFRACTION' 1.990 2.040 50 . 4829 . 0.153 0.167 . 261 . . 5090 . 'X-RAY DIFFRACTION' 2.040 2.090 50 . 4884 . 0.156 0.196 . 237 . . 5121 . 'X-RAY DIFFRACTION' 2.090 2.150 50 . 4871 . 0.152 0.167 . 276 . . 5147 . 'X-RAY DIFFRACTION' 2.150 2.220 50 . 4888 . 0.157 0.176 . 241 . . 5129 . 'X-RAY DIFFRACTION' 2.220 2.300 50 . 4863 . 0.149 0.177 . 263 . . 5126 . 'X-RAY DIFFRACTION' 2.300 2.390 50 . 4879 . 0.150 0.189 . 267 . . 5146 . 'X-RAY DIFFRACTION' 2.390 2.500 50 . 4867 . 0.151 0.164 . 287 . . 5154 . 'X-RAY DIFFRACTION' 2.500 2.640 50 . 4919 . 0.155 0.180 . 257 . . 5176 . 'X-RAY DIFFRACTION' 2.640 2.800 50 . 4915 . 0.159 0.176 . 256 . . 5171 . 'X-RAY DIFFRACTION' 2.800 3.020 50 . 4972 . 0.160 0.187 . 242 . . 5214 . 'X-RAY DIFFRACTION' 3.020 3.320 50 . 4969 . 0.154 0.164 . 263 . . 5232 . 'X-RAY DIFFRACTION' 3.320 3.800 50 . 4966 . 0.142 0.156 . 289 . . 5255 . 'X-RAY DIFFRACTION' 3.800 4.780 50 . 5004 . 0.139 0.143 . 307 . . 5311 . 'X-RAY DIFFRACTION' # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 protein_rep.param protein_rep.top 'X-RAY DIFFRACTION' 2 carbohydrate.param carbohydrate.top 'X-RAY DIFFRACTION' 3 cis_peptide.param cis_peptide.top 'X-RAY DIFFRACTION' 4 water_rep.param water_rep.top 'X-RAY DIFFRACTION' 5 ion.param ion.top 'X-RAY DIFFRACTION' # _struct.entry_id 3BLB _struct.title 'Crystal structure of Golgi Mannosidase II in complex with swainsonine at 1.3 Angstrom resolution' _struct.pdbx_descriptor 'Alpha-mannosidase 2 (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 3BLB _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'Golgi mannosidase, Glycosidase, Golgi apparatus, Hydrolase, Membrane, Signal-anchor, Transmembrane' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? HIS A 139 ? GLU A 130 HIS A 139 1 ? 10 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? MET A 290 ? GLN A 284 MET A 290 5 ? 7 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.056 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.049 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.087 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.061 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 2.040 ? metalc1 metalc ? ? A HIS 90 NE2 ? ? ? 1_555 C ZN . ZN ? ? A HIS 90 A ZN 1047 1_555 ? ? ? ? ? ? ? 2.099 ? metalc2 metalc ? ? A ASP 92 OD1 ? ? ? 1_555 C ZN . ZN ? ? A ASP 92 A ZN 1047 1_555 ? ? ? ? ? ? ? 2.240 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 1046 1_555 ? ? ? ? ? ? ? 1.444 ? metalc3 metalc ? ? A ASP 204 OD2 ? ? ? 1_555 C ZN . ZN ? ? A ASP 204 A ZN 1047 1_555 ? ? ? ? ? ? ? 2.167 ? metalc4 metalc ? ? A HIS 471 NE2 ? ? ? 1_555 C ZN . ZN ? ? A HIS 471 A ZN 1047 1_555 ? ? ? ? ? ? ? 2.087 ? metalc5 metalc ? ? C ZN . ZN ? ? ? 1_555 D SWA . O11 ? ? A ZN 1047 A SWA 1048 1_555 ? ? ? ? ? ? ? 2.202 ? metalc6 metalc ? ? C ZN . ZN ? ? ? 1_555 D SWA . O13 ? ? A ZN 1047 A SWA 1048 1_555 ? ? ? ? ? ? ? 2.131 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 -2.70 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 -0.98 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 2 ? E ? 6 ? F ? 5 ? G ? 5 ? H ? 12 ? I ? 5 ? J ? 8 ? K ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel H 6 7 ? anti-parallel H 7 8 ? anti-parallel H 8 9 ? anti-parallel H 9 10 ? anti-parallel H 10 11 ? anti-parallel H 11 12 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel J 6 7 ? anti-parallel J 7 8 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASP A 341 ? VAL A 333 ASP A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 ALA A 408 ? ARG A 410 ? ALA A 408 ARG A 410 D 2 ASN A 413 ? TYR A 414 ? ASN A 413 TYR A 414 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 E 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 F 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 F 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 F 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 F 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 F 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 G 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 G 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 G 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 G 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 G 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 H 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 H 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 H 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 H 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 H 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 H 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 H 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 H 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 H 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 H 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 H 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 H 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 I 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 J 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 J 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 J 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 J 4 HIS A 705 ? TYR A 715 ? HIS A 705 TYR A 715 J 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 J 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 J 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 J 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 K 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 K 2 GLN A 973 ? ARG A 981 ? GLN A 973 ARG A 981 K 3 THR A 1036 ? HIS A 1043 ? THR A 1036 HIS A 1043 K 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 K 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O SER A 401 ? O SER A 401 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O LEU A 225 ? O LEU A 225 N ALA A 202 ? N ALA A 202 B 1 2 O LEU A 334 ? O LEU A 334 N LYS A 82 ? N LYS A 82 B 2 3 N VAL A 85 ? N VAL A 85 O GLN A 375 ? O GLN A 375 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N ARG A 410 ? N ARG A 410 O ASN A 413 ? O ASN A 413 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 E 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 F 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 F 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 F 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 F 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 G 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 G 2 3 N PHE A 571 ? N PHE A 571 O ILE A 618 ? O ILE A 618 G 3 4 O GLN A 610 ? O GLN A 610 N SER A 597 ? N SER A 597 G 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 H 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 H 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 H 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 H 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 H 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 H 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 H 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 H 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 H 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 H 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 H 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 J 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 J 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 J 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 J 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 J 5 6 N ILE A 790 ? N ILE A 790 O GLN A 866 ? O GLN A 866 J 6 7 O MET A 865 ? O MET A 865 N GLY A 853 ? N GLY A 853 J 7 8 O GLY A 854 ? O GLY A 854 N TYR A 829 ? N TYR A 829 K 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 K 2 3 N LEU A 979 ? N LEU A 979 O ALA A 1037 ? O ALA A 1037 K 3 4 O SER A 1042 ? O SER A 1042 N ALA A 1007 ? N ALA A 1007 K 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 1046' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE ZN A 1047' AC3 Software ? ? ? ? 12 'BINDING SITE FOR RESIDUE SWA A 1048' AC4 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE MRD A 1049' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 2 LYS A 154 ? LYS A 154 . ? 1_555 ? 2 AC1 2 ASN A 194 ? ASN A 194 . ? 1_555 ? 3 AC2 5 HIS A 90 ? HIS A 90 . ? 1_555 ? 4 AC2 5 ASP A 92 ? ASP A 92 . ? 1_555 ? 5 AC2 5 ASP A 204 ? ASP A 204 . ? 1_555 ? 6 AC2 5 HIS A 471 ? HIS A 471 . ? 1_555 ? 7 AC2 5 SWA D . ? SWA A 1048 . ? 1_555 ? 8 AC3 12 HIS A 90 ? HIS A 90 . ? 1_555 ? 9 AC3 12 ASP A 92 ? ASP A 92 . ? 1_555 ? 10 AC3 12 TRP A 95 ? TRP A 95 . ? 1_555 ? 11 AC3 12 ASP A 204 ? ASP A 204 . ? 1_555 ? 12 AC3 12 PHE A 206 ? PHE A 206 . ? 1_555 ? 13 AC3 12 ARG A 228 ? ARG A 228 . ? 1_555 ? 14 AC3 12 TYR A 269 ? TYR A 269 . ? 1_555 ? 15 AC3 12 ASP A 341 ? ASP A 341 . ? 1_555 ? 16 AC3 12 HIS A 471 ? HIS A 471 . ? 1_555 ? 17 AC3 12 ASP A 472 ? ASP A 472 . ? 1_555 ? 18 AC3 12 TYR A 727 ? TYR A 727 . ? 1_555 ? 19 AC3 12 ZN C . ? ZN A 1047 . ? 1_555 ? 20 AC4 8 LYS A 63 ? LYS A 63 . ? 1_555 ? 21 AC4 8 GLN A 64 ? GLN A 64 . ? 1_555 ? 22 AC4 8 TYR A 267 ? TYR A 267 . ? 1_555 ? 23 AC4 8 HIS A 273 ? HIS A 273 . ? 1_555 ? 24 AC4 8 HOH F . ? HOH A 1339 . ? 1_555 ? 25 AC4 8 HOH F . ? HOH A 1813 . ? 1_555 ? 26 AC4 8 HOH F . ? HOH A 1927 . ? 1_555 ? 27 AC4 8 HOH F . ? HOH A 1929 . ? 1_555 ? # _database_PDB_matrix.entry_id 3BLB _database_PDB_matrix.origx[1][1] 1.00000 _database_PDB_matrix.origx[1][2] 0.00000 _database_PDB_matrix.origx[1][3] 0.00000 _database_PDB_matrix.origx[2][1] 0.00000 _database_PDB_matrix.origx[2][2] 1.00000 _database_PDB_matrix.origx[2][3] 0.00000 _database_PDB_matrix.origx[3][1] 0.00000 _database_PDB_matrix.origx[3][2] 0.00000 _database_PDB_matrix.origx[3][3] 1.00000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 3BLB _atom_sites.fract_transf_matrix[1][1] 0.01454 _atom_sites.fract_transf_matrix[1][2] 0.00000 _atom_sites.fract_transf_matrix[1][3] 0.00000 _atom_sites.fract_transf_matrix[2][1] 0.00000 _atom_sites.fract_transf_matrix[2][2] 0.00912 _atom_sites.fract_transf_matrix[2][3] 0.00000 _atom_sites.fract_transf_matrix[3][1] 0.00000 _atom_sites.fract_transf_matrix[3][2] 0.00000 _atom_sites.fract_transf_matrix[3][3] 0.00720 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . CYS A 1 31 ? 44.035 36.106 -19.271 1.00 23.84 ? 31 CYS A N 1 ATOM 2 C CA . CYS A 1 31 ? 43.339 37.313 -18.707 1.00 19.60 ? 31 CYS A CA 1 ATOM 3 C C . CYS A 1 31 ? 41.847 37.087 -18.751 1.00 19.29 ? 31 CYS A C 1 ATOM 4 O O . CYS A 1 31 ? 41.357 36.492 -19.726 1.00 20.53 ? 31 CYS A O 1 ATOM 5 C CB . CYS A 1 31 ? 43.609 38.513 -19.569 1.00 18.32 ? 31 CYS A CB 1 ATOM 6 S SG . CYS A 1 31 ? 45.319 39.131 -19.580 1.00 22.12 ? 31 CYS A SG 1 ATOM 7 N N . GLN A 1 32 ? 41.131 37.539 -17.731 1.00 18.01 ? 32 GLN A N 1 ATOM 8 C CA . GLN A 1 32 ? 39.662 37.495 -17.729 1.00 17.62 ? 32 GLN A CA 1 ATOM 9 C C . GLN A 1 32 ? 39.137 38.451 -18.815 1.00 14.90 ? 32 GLN A C 1 ATOM 10 O O . GLN A 1 32 ? 39.718 39.530 -19.067 1.00 15.61 ? 32 GLN A O 1 ATOM 11 C CB . GLN A 1 32 ? 39.042 38.068 -16.439 1.00 20.07 ? 32 GLN A CB 1 ATOM 12 C CG . GLN A 1 32 ? 39.209 37.273 -15.217 1.00 26.02 ? 32 GLN A CG 1 ATOM 13 C CD . GLN A 1 32 ? 38.149 37.665 -14.198 1.00 29.14 ? 32 GLN A CD 1 ATOM 14 O OE1 . GLN A 1 32 ? 37.024 37.161 -14.232 1.00 29.63 ? 32 GLN A OE1 1 ATOM 15 N NE2 . GLN A 1 32 ? 38.495 38.589 -13.300 1.00 28.68 ? 32 GLN A NE2 1 ATOM 16 N N . ASP A 1 33 ? 38.036 38.064 -19.455 1.00 18.70 ? 33 ASP A N 1 ATOM 17 C CA . ASP A 1 33 ? 37.390 38.905 -20.476 1.00 13.20 ? 33 ASP A CA 1 ATOM 18 C C . ASP A 1 33 ? 36.465 39.837 -19.673 1.00 16.86 ? 33 ASP A C 1 ATOM 19 O O . ASP A 1 33 ? 35.558 39.401 -18.982 1.00 20.65 ? 33 ASP A O 1 ATOM 20 C CB . ASP A 1 33 ? 36.609 37.992 -21.443 1.00 16.26 ? 33 ASP A CB 1 ATOM 21 C CG . ASP A 1 33 ? 35.894 38.711 -22.559 1.00 20.36 ? 33 ASP A CG 1 ATOM 22 O OD1 . ASP A 1 33 ? 35.418 39.844 -22.420 1.00 17.42 ? 33 ASP A OD1 1 ATOM 23 O OD2 . ASP A 1 33 ? 35.727 38.045 -23.602 1.00 22.54 ? 33 ASP A OD2 1 ATOM 24 N N . VAL A 1 34 ? 36.695 41.132 -19.796 1.00 10.33 ? 34 VAL A N 1 ATOM 25 C CA . VAL A 1 34 ? 35.936 42.127 -19.034 1.00 10.21 ? 34 VAL A CA 1 ATOM 26 C C . VAL A 1 34 ? 34.727 42.704 -19.775 1.00 8.86 ? 34 VAL A C 1 ATOM 27 O O . VAL A 1 34 ? 34.005 43.603 -19.285 1.00 9.48 ? 34 VAL A O 1 ATOM 28 C CB . VAL A 1 34 ? 36.873 43.295 -18.577 1.00 9.28 ? 34 VAL A CB 1 ATOM 29 C CG1 . VAL A 1 34 ? 38.106 42.750 -17.839 1.00 11.21 ? 34 VAL A CG1 1 ATOM 30 C CG2 . VAL A 1 34 ? 37.333 44.151 -19.774 1.00 10.89 ? 34 VAL A CG2 1 ATOM 31 N N . VAL A 1 35 ? 34.477 42.175 -20.980 1.00 9.45 ? 35 VAL A N 1 ATOM 32 C CA . VAL A 1 35 ? 33.385 42.654 -21.823 1.00 9.19 ? 35 VAL A CA 1 ATOM 33 C C . VAL A 1 35 ? 32.195 41.727 -22.010 1.00 8.17 ? 35 VAL A C 1 ATOM 34 O O . VAL A 1 35 ? 31.068 42.145 -21.955 1.00 9.57 ? 35 VAL A O 1 ATOM 35 C CB . VAL A 1 35 ? 33.935 42.969 -23.231 1.00 10.51 ? 35 VAL A CB 1 ATOM 36 C CG1 . VAL A 1 35 ? 32.803 43.431 -24.185 1.00 10.95 ? 35 VAL A CG1 1 ATOM 37 C CG2 . VAL A 1 35 ? 35.008 44.091 -23.112 1.00 11.29 ? 35 VAL A CG2 1 ATOM 38 N N . GLN A 1 36 ? 32.520 40.463 -22.262 1.00 10.82 ? 36 GLN A N 1 ATOM 39 C CA . GLN A 1 36 ? 31.516 39.490 -22.742 1.00 13.02 ? 36 GLN A CA 1 ATOM 40 C C . GLN A 1 36 ? 30.866 38.564 -21.780 1.00 17.77 ? 36 GLN A C 1 ATOM 41 O O . GLN A 1 36 ? 29.983 37.833 -22.190 1.00 23.03 ? 36 GLN A O 1 ATOM 42 C CB . GLN A 1 36 ? 32.209 38.653 -23.798 1.00 11.63 ? 36 GLN A CB 1 ATOM 43 C CG . GLN A 1 36 ? 32.849 39.525 -24.893 1.00 14.31 ? 36 GLN A CG 1 ATOM 44 C CD . GLN A 1 36 ? 33.364 38.679 -26.035 1.00 12.82 ? 36 GLN A CD 1 ATOM 45 O OE1 . GLN A 1 36 ? 32.675 38.552 -27.063 1.00 17.20 ? 36 GLN A OE1 1 ATOM 46 N NE2 . GLN A 1 36 ? 34.544 38.111 -25.876 1.00 14.28 ? 36 GLN A NE2 1 ATOM 47 N N . ASP A 1 37 ? 31.314 38.531 -20.539 1.00 16.17 ? 37 ASP A N 1 ATOM 48 C CA . ASP A 1 37 ? 30.787 37.641 -19.519 1.00 19.08 ? 37 ASP A CA 1 ATOM 49 C C . ASP A 1 37 ? 30.152 38.490 -18.403 1.00 17.65 ? 37 ASP A C 1 ATOM 50 O O . ASP A 1 37 ? 30.879 39.144 -17.666 1.00 22.57 ? 37 ASP A O 1 ATOM 51 C CB . ASP A 1 37 ? 31.937 36.814 -18.891 1.00 21.83 ? 37 ASP A CB 1 ATOM 52 C CG . ASP A 1 37 ? 32.594 35.827 -19.879 1.00 26.24 ? 37 ASP A CG 1 ATOM 53 O OD1 . ASP A 1 37 ? 31.846 35.241 -20.676 1.00 28.80 ? 37 ASP A OD1 1 ATOM 54 O OD2 . ASP A 1 37 ? 33.841 35.664 -19.835 1.00 26.88 ? 37 ASP A OD2 1 ATOM 55 N N . VAL A 1 38 ? 28.843 38.479 -18.276 1.00 14.90 ? 38 VAL A N 1 ATOM 56 C CA . VAL A 1 38 ? 28.174 39.230 -17.204 1.00 13.68 ? 38 VAL A CA 1 ATOM 57 C C . VAL A 1 38 ? 28.359 38.502 -15.859 1.00 15.13 ? 38 VAL A C 1 ATOM 58 O O . VAL A 1 38 ? 27.894 37.358 -15.689 1.00 16.33 ? 38 VAL A O 1 ATOM 59 C CB . VAL A 1 38 ? 26.668 39.373 -17.511 1.00 15.43 ? 38 VAL A CB 1 ATOM 60 C CG1 . VAL A 1 38 ? 25.924 40.117 -16.350 1.00 15.17 ? 38 VAL A CG1 1 ATOM 61 C CG2 . VAL A 1 38 ? 26.510 40.071 -18.921 1.00 15.00 ? 38 VAL A CG2 1 ATOM 62 N N . PRO A 1 39 ? 28.994 39.134 -14.863 1.00 13.05 ? 39 PRO A N 1 ATOM 63 C CA . PRO A 1 39 ? 29.182 38.440 -13.583 1.00 13.72 ? 39 PRO A CA 1 ATOM 64 C C . PRO A 1 39 ? 27.898 38.086 -12.921 1.00 12.83 ? 39 PRO A C 1 ATOM 65 O O . PRO A 1 39 ? 26.922 38.809 -12.963 1.00 12.97 ? 39 PRO A O 1 ATOM 66 C CB . PRO A 1 39 ? 29.935 39.459 -12.722 1.00 13.41 ? 39 PRO A CB 1 ATOM 67 C CG . PRO A 1 39 ? 30.711 40.297 -13.788 1.00 11.66 ? 39 PRO A CG 1 ATOM 68 C CD . PRO A 1 39 ? 29.692 40.449 -14.898 1.00 12.94 ? 39 PRO A CD 1 ATOM 69 N N . ASN A 1 40 ? 27.901 36.888 -12.293 1.00 12.85 ? 40 ASN A N 1 ATOM 70 C CA . ASN A 1 40 ? 26.727 36.491 -11.535 1.00 15.29 ? 40 ASN A CA 1 ATOM 71 C C . ASN A 1 40 ? 26.950 36.868 -10.049 1.00 13.75 ? 40 ASN A C 1 ATOM 72 O O . ASN A 1 40 ? 27.837 36.310 -9.385 1.00 16.37 ? 40 ASN A O 1 ATOM 73 C CB . ASN A 1 40 ? 26.501 34.984 -11.708 1.00 18.37 ? 40 ASN A CB 1 ATOM 74 C CG . ASN A 1 40 ? 25.454 34.447 -10.784 1.00 26.42 ? 40 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 40 ? 24.414 35.075 -10.544 1.00 29.68 ? 40 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 40 ? 25.707 33.248 -10.259 1.00 34.21 ? 40 ASN A ND2 1 ATOM 77 N N . VAL A 1 41 ? 26.215 37.851 -9.557 1.00 11.38 ? 41 VAL A N 1 ATOM 78 C CA . VAL A 1 41 ? 26.414 38.329 -8.189 1.00 10.39 ? 41 VAL A CA 1 ATOM 79 C C . VAL A 1 41 ? 25.071 38.352 -7.482 1.00 11.59 ? 41 VAL A C 1 ATOM 80 O O . VAL A 1 41 ? 24.047 38.499 -8.129 1.00 13.27 ? 41 VAL A O 1 ATOM 81 C CB . VAL A 1 41 ? 27.055 39.754 -8.151 1.00 10.99 ? 41 VAL A CB 1 ATOM 82 C CG1 . VAL A 1 41 ? 28.491 39.701 -8.609 1.00 11.43 ? 41 VAL A CG1 1 ATOM 83 C CG2 . VAL A 1 41 ? 26.242 40.742 -8.988 1.00 11.85 ? 41 VAL A CG2 1 ATOM 84 N N . ASP A 1 42 ? 25.062 38.215 -6.159 1.00 10.12 ? 42 ASP A N 1 ATOM 85 C CA . ASP A 1 42 ? 23.808 38.255 -5.457 1.00 10.58 ? 42 ASP A CA 1 ATOM 86 C C . ASP A 1 42 ? 23.125 39.591 -5.477 1.00 10.47 ? 42 ASP A C 1 ATOM 87 O O . ASP A 1 42 ? 21.892 39.706 -5.483 1.00 12.16 ? 42 ASP A O 1 ATOM 88 C CB . ASP A 1 42 ? 24.011 37.838 -3.981 1.00 12.00 ? 42 ASP A CB 1 ATOM 89 C CG . ASP A 1 42 ? 24.552 36.438 -3.875 1.00 15.64 ? 42 ASP A CG 1 ATOM 90 O OD1 . ASP A 1 42 ? 23.884 35.480 -4.431 1.00 17.76 ? 42 ASP A OD1 1 ATOM 91 O OD2 . ASP A 1 42 ? 25.597 36.177 -3.284 1.00 13.67 ? 42 ASP A OD2 1 ATOM 92 N N . VAL A 1 43 ? 23.925 40.674 -5.403 1.00 8.73 ? 43 VAL A N 1 ATOM 93 C CA . VAL A 1 43 ? 23.394 42.026 -5.427 1.00 10.88 ? 43 VAL A CA 1 ATOM 94 C C . VAL A 1 43 ? 24.176 42.827 -6.480 1.00 8.65 ? 43 VAL A C 1 ATOM 95 O O . VAL A 1 43 ? 25.392 42.909 -6.423 1.00 9.57 ? 43 VAL A O 1 ATOM 96 C CB . VAL A 1 43 ? 23.569 42.751 -4.090 1.00 9.13 ? 43 VAL A CB 1 ATOM 97 C CG1 . VAL A 1 43 ? 22.990 44.180 -4.171 1.00 10.43 ? 43 VAL A CG1 1 ATOM 98 C CG2 . VAL A 1 43 ? 22.844 41.970 -2.930 1.00 13.02 ? 43 VAL A CG2 1 ATOM 99 N N . GLN A 1 44 ? 23.470 43.318 -7.489 1.00 8.25 ? 44 GLN A N 1 ATOM 100 C CA . GLN A 1 44 ? 24.056 44.174 -8.542 1.00 8.81 ? 44 GLN A CA 1 ATOM 101 C C . GLN A 1 44 ? 23.345 45.499 -8.377 1.00 7.80 ? 44 GLN A C 1 ATOM 102 O O . GLN A 1 44 ? 22.130 45.569 -8.555 1.00 8.44 ? 44 GLN A O 1 ATOM 103 C CB . GLN A 1 44 ? 23.876 43.540 -9.930 1.00 9.19 ? 44 GLN A CB 1 ATOM 104 C CG . GLN A 1 44 ? 24.984 43.949 -10.894 1.00 7.94 ? 44 GLN A CG 1 ATOM 105 C CD . GLN A 1 44 ? 25.047 45.492 -11.035 1.00 7.57 ? 44 GLN A CD 1 ATOM 106 O OE1 . GLN A 1 44 ? 24.034 46.093 -11.379 1.00 8.82 ? 44 GLN A OE1 1 ATOM 107 N NE2 . GLN A 1 44 ? 26.216 46.103 -10.712 1.00 7.36 ? 44 GLN A NE2 1 ATOM 108 N N . MET A 1 45 ? 24.057 46.581 -8.012 1.00 7.26 ? 45 MET A N 1 ATOM 109 C CA . MET A 1 45 ? 23.364 47.806 -7.634 1.00 7.49 ? 45 MET A CA 1 ATOM 110 C C . MET A 1 45 ? 22.465 48.463 -8.667 1.00 6.90 ? 45 MET A C 1 ATOM 111 O O . MET A 1 45 ? 21.472 49.074 -8.300 1.00 7.97 ? 45 MET A O 1 ATOM 112 C CB . MET A 1 45 ? 24.355 48.829 -7.056 1.00 7.74 ? 45 MET A CB 1 ATOM 113 C CG . MET A 1 45 ? 24.973 48.334 -5.719 1.00 8.30 ? 45 MET A CG 1 ATOM 114 S SD . MET A 1 45 ? 23.773 48.059 -4.420 1.00 10.83 ? 45 MET A SD 1 ATOM 115 C CE . MET A 1 45 ? 23.109 49.739 -4.283 1.00 12.64 ? 45 MET A CE 1 ATOM 116 N N . LEU A 1 46 ? 22.832 48.353 -9.932 1.00 7.52 ? 46 LEU A N 1 ATOM 117 C CA . LEU A 1 46 ? 21.952 48.936 -10.976 1.00 8.08 ? 46 LEU A CA 1 ATOM 118 C C . LEU A 1 46 ? 20.617 48.159 -11.035 1.00 9.02 ? 46 LEU A C 1 ATOM 119 O O . LEU A 1 46 ? 19.554 48.753 -11.154 1.00 9.55 ? 46 LEU A O 1 ATOM 120 C CB . LEU A 1 46 ? 22.659 48.927 -12.325 1.00 9.59 ? 46 LEU A CB 1 ATOM 121 C CG . LEU A 1 46 ? 21.863 49.658 -13.437 1.00 9.88 ? 46 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 46 ? 21.908 51.201 -13.222 1.00 10.18 ? 46 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 46 ? 22.459 49.312 -14.773 1.00 12.32 ? 46 LEU A CD2 1 ATOM 124 N N . GLU A 1 47 ? 20.707 46.833 -10.885 1.00 9.33 ? 47 GLU A N 1 ATOM 125 C CA . GLU A 1 47 ? 19.503 45.984 -10.929 1.00 10.99 ? 47 GLU A CA 1 ATOM 126 C C . GLU A 1 47 ? 18.695 46.269 -9.688 1.00 11.00 ? 47 GLU A C 1 ATOM 127 O O . GLU A 1 47 ? 17.456 46.427 -9.718 1.00 11.92 ? 47 GLU A O 1 ATOM 128 C CB . GLU A 1 47 ? 19.920 44.516 -11.017 1.00 11.93 ? 47 GLU A CB 1 ATOM 129 C CG . GLU A 1 47 ? 18.703 43.565 -11.254 1.00 17.55 ? 47 GLU A CG 1 ATOM 130 C CD . GLU A 1 47 ? 17.907 43.210 -10.000 1.00 27.38 ? 47 GLU A CD 1 ATOM 131 O OE1 . GLU A 1 47 ? 18.404 43.352 -8.853 1.00 23.15 ? 47 GLU A OE1 1 ATOM 132 O OE2 . GLU A 1 47 ? 16.739 42.753 -10.153 1.00 29.75 ? 47 GLU A OE2 1 ATOM 133 N N . LEU A 1 48 ? 19.353 46.399 -8.531 1.00 9.73 ? 48 LEU A N 1 ATOM 134 C CA . LEU A 1 48 ? 18.642 46.722 -7.302 1.00 9.06 ? 48 LEU A CA 1 ATOM 135 C C . LEU A 1 48 ? 17.898 48.046 -7.416 1.00 9.04 ? 48 LEU A C 1 ATOM 136 O O . LEU A 1 48 ? 16.718 48.168 -7.049 1.00 11.32 ? 48 LEU A O 1 ATOM 137 C CB . LEU A 1 48 ? 19.632 46.744 -6.112 1.00 10.66 ? 48 LEU A CB 1 ATOM 138 C CG . LEU A 1 48 ? 18.934 46.962 -4.771 1.00 12.68 ? 48 LEU A CG 1 ATOM 139 C CD1 . LEU A 1 48 ? 17.934 45.804 -4.508 1.00 18.75 ? 48 LEU A CD1 1 ATOM 140 C CD2 . LEU A 1 48 ? 19.958 47.099 -3.656 1.00 18.00 ? 48 LEU A CD2 1 ATOM 141 N N . TYR A 1 49 ? 18.580 49.044 -7.960 1.00 9.59 ? 49 TYR A N 1 ATOM 142 C CA . TYR A 1 49 ? 17.999 50.364 -8.168 1.00 9.05 ? 49 TYR A CA 1 ATOM 143 C C . TYR A 1 49 ? 16.739 50.303 -9.032 1.00 9.46 ? 49 TYR A C 1 ATOM 144 O O . TYR A 1 49 ? 15.790 51.004 -8.787 1.00 11.12 ? 49 TYR A O 1 ATOM 145 C CB . TYR A 1 49 ? 19.048 51.342 -8.745 1.00 9.50 ? 49 TYR A CB 1 ATOM 146 C CG . TYR A 1 49 ? 19.577 52.283 -7.694 1.00 7.98 ? 49 TYR A CG 1 ATOM 147 C CD1 . TYR A 1 49 ? 20.029 51.803 -6.472 1.00 8.75 ? 49 TYR A CD1 1 ATOM 148 C CD2 . TYR A 1 49 ? 19.600 53.647 -7.904 1.00 9.85 ? 49 TYR A CD2 1 ATOM 149 C CE1 . TYR A 1 49 ? 20.467 52.648 -5.499 1.00 8.37 ? 49 TYR A CE1 1 ATOM 150 C CE2 . TYR A 1 49 ? 20.050 54.508 -6.910 1.00 9.62 ? 49 TYR A CE2 1 ATOM 151 C CZ . TYR A 1 49 ? 20.473 53.999 -5.713 1.00 7.99 ? 49 TYR A CZ 1 ATOM 152 O OH . TYR A 1 49 ? 20.907 54.849 -4.738 1.00 9.76 ? 49 TYR A OH 1 ATOM 153 N N . ASP A 1 50 ? 16.757 49.462 -10.044 1.00 10.61 ? 50 ASP A N 1 ATOM 154 C CA . ASP A 1 50 ? 15.621 49.351 -10.984 1.00 13.49 ? 50 ASP A CA 1 ATOM 155 C C . ASP A 1 50 ? 14.401 48.771 -10.274 1.00 14.39 ? 50 ASP A C 1 ATOM 156 O O . ASP A 1 50 ? 13.269 49.189 -10.610 1.00 14.34 ? 50 ASP A O 1 ATOM 157 C CB . ASP A 1 50 ? 16.050 48.504 -12.180 1.00 14.56 ? 50 ASP A CB 1 ATOM 158 C CG . ASP A 1 50 ? 15.244 48.760 -13.447 1.00 20.90 ? 50 ASP A CG 1 ATOM 159 O OD1 . ASP A 1 50 ? 14.567 49.784 -13.540 1.00 24.56 ? 50 ASP A OD1 1 ATOM 160 O OD2 . ASP A 1 50 ? 15.365 47.896 -14.355 1.00 28.50 ? 50 ASP A OD2 1 ATOM 161 N N . ARG A 1 51 ? 14.608 47.881 -9.304 1.00 13.40 ? 51 ARG A N 1 ATOM 162 C CA . ARG A 1 51 ? 13.505 47.209 -8.560 1.00 15.84 ? 51 ARG A CA 1 ATOM 163 C C . ARG A 1 51 ? 13.037 47.949 -7.311 1.00 16.18 ? 51 ARG A C 1 ATOM 164 O O . ARG A 1 51 ? 11.856 47.870 -6.950 1.00 19.22 ? 51 ARG A O 1 ATOM 165 C CB . ARG A 1 51 ? 13.936 45.798 -8.081 1.00 22.23 ? 51 ARG A CB 1 ATOM 166 C CG . ARG A 1 51 ? 14.593 44.938 -9.085 1.00 30.27 ? 51 ARG A CG 1 ATOM 167 C CD . ARG A 1 51 ? 14.926 43.551 -8.496 1.00 33.66 ? 51 ARG A CD 1 ATOM 168 N NE . ARG A 1 51 ? 14.770 43.508 -7.048 1.00 38.12 ? 51 ARG A NE 1 ATOM 169 C CZ . ARG A 1 51 ? 15.753 43.260 -6.189 1.00 36.78 ? 51 ARG A CZ 1 ATOM 170 N NH1 . ARG A 1 51 ? 16.986 43.022 -6.626 1.00 37.83 ? 51 ARG A NH1 1 ATOM 171 N NH2 . ARG A 1 51 ? 15.493 43.264 -4.884 1.00 39.74 ? 51 ARG A NH2 1 ATOM 172 N N . MET A 1 52 ? 13.906 48.674 -6.621 1.00 14.12 ? 52 MET A N 1 ATOM 173 C CA . MET A 1 52 ? 13.528 49.381 -5.389 1.00 16.90 ? 52 MET A CA 1 ATOM 174 C C . MET A 1 52 ? 12.532 50.491 -5.549 1.00 13.40 ? 52 MET A C 1 ATOM 175 O O . MET A 1 52 ? 12.560 51.207 -6.545 1.00 15.92 ? 52 MET A O 1 ATOM 176 C CB . MET A 1 52 ? 14.773 50.055 -4.726 1.00 17.19 ? 52 MET A CB 1 ATOM 177 C CG . MET A 1 52 ? 15.718 49.070 -4.114 1.00 16.72 ? 52 MET A CG 1 ATOM 178 S SD . MET A 1 52 ? 17.313 49.981 -3.672 1.00 18.66 ? 52 MET A SD 1 ATOM 179 C CE . MET A 1 52 ? 16.729 51.269 -2.550 1.00 17.55 ? 52 MET A CE 1 ATOM 180 N N . SER A 1 53 ? 11.677 50.712 -4.539 1.00 15.22 ? 53 SER A N 1 ATOM 181 C CA . SER A 1 53 ? 10.687 51.801 -4.633 1.00 18.34 ? 53 SER A CA 1 ATOM 182 C C . SER A 1 53 ? 11.100 53.143 -4.007 1.00 15.08 ? 53 SER A C 1 ATOM 183 O O . SER A 1 53 ? 10.494 54.189 -4.253 1.00 17.71 ? 53 SER A O 1 ATOM 184 C CB . SER A 1 53 ? 9.368 51.327 -4.011 1.00 18.90 ? 53 SER A CB 1 ATOM 185 O OG A SER A 1 53 ? 8.824 50.292 -4.805 0.50 27.66 ? 53 SER A OG 1 ATOM 186 O OG B SER A 1 53 ? 9.422 51.332 -2.645 0.50 31.08 ? 53 SER A OG 1 ATOM 187 N N . PHE A 1 54 ? 12.102 53.104 -3.153 1.00 12.93 ? 54 PHE A N 1 ATOM 188 C CA . PHE A 1 54 ? 12.612 54.300 -2.511 1.00 12.03 ? 54 PHE A CA 1 ATOM 189 C C . PHE A 1 54 ? 11.597 55.078 -1.710 1.00 13.43 ? 54 PHE A C 1 ATOM 190 O O . PHE A 1 54 ? 11.692 56.304 -1.556 1.00 14.87 ? 54 PHE A O 1 ATOM 191 C CB . PHE A 1 54 ? 13.279 55.238 -3.570 1.00 12.64 ? 54 PHE A CB 1 ATOM 192 C CG . PHE A 1 54 ? 14.530 54.656 -4.222 1.00 10.32 ? 54 PHE A CG 1 ATOM 193 C CD1 . PHE A 1 54 ? 14.450 53.855 -5.340 1.00 10.92 ? 54 PHE A CD1 1 ATOM 194 C CD2 . PHE A 1 54 ? 15.792 54.973 -3.707 1.00 10.26 ? 54 PHE A CD2 1 ATOM 195 C CE1 . PHE A 1 54 ? 15.619 53.359 -5.963 1.00 10.87 ? 54 PHE A CE1 1 ATOM 196 C CE2 . PHE A 1 54 ? 16.935 54.501 -4.320 1.00 11.34 ? 54 PHE A CE2 1 ATOM 197 C CZ . PHE A 1 54 ? 16.857 53.698 -5.447 1.00 10.62 ? 54 PHE A CZ 1 ATOM 198 N N . LYS A 1 55 ? 10.571 54.408 -1.175 1.00 13.50 ? 55 LYS A N 1 ATOM 199 C CA . LYS A 1 55 ? 9.590 55.201 -0.395 1.00 13.42 ? 55 LYS A CA 1 ATOM 200 C C . LYS A 1 55 ? 10.151 55.628 0.925 1.00 14.13 ? 55 LYS A C 1 ATOM 201 O O . LYS A 1 55 ? 10.755 54.826 1.627 1.00 17.24 ? 55 LYS A O 1 ATOM 202 C CB . LYS A 1 55 ? 8.324 54.356 -0.110 1.00 13.98 ? 55 LYS A CB 1 ATOM 203 C CG . LYS A 1 55 ? 7.680 53.857 -1.327 1.00 15.46 ? 55 LYS A CG 1 ATOM 204 C CD . LYS A 1 55 ? 7.384 54.970 -2.345 1.00 14.34 ? 55 LYS A CD 1 ATOM 205 C CE . LYS A 1 55 ? 6.572 54.414 -3.526 1.00 20.24 ? 55 LYS A CE 1 ATOM 206 N NZ . LYS A 1 55 ? 6.262 55.493 -4.517 1.00 19.83 ? 55 LYS A NZ 1 ATOM 207 N N . ASP A 1 56 ? 9.951 56.876 1.278 1.00 13.40 ? 56 ASP A N 1 ATOM 208 C CA . ASP A 1 56 ? 10.440 57.442 2.504 1.00 13.55 ? 56 ASP A CA 1 ATOM 209 C C . ASP A 1 56 ? 9.368 57.352 3.622 1.00 14.91 ? 56 ASP A C 1 ATOM 210 O O . ASP A 1 56 ? 8.751 58.353 4.007 1.00 18.12 ? 56 ASP A O 1 ATOM 211 C CB . ASP A 1 56 ? 10.862 58.882 2.219 1.00 14.09 ? 56 ASP A CB 1 ATOM 212 C CG . ASP A 1 56 ? 11.536 59.534 3.406 1.00 14.32 ? 56 ASP A CG 1 ATOM 213 O OD1 . ASP A 1 56 ? 12.047 58.830 4.307 1.00 14.38 ? 56 ASP A OD1 1 ATOM 214 O OD2 . ASP A 1 56 ? 11.552 60.781 3.470 1.00 16.19 ? 56 ASP A OD2 1 ATOM 215 N N . ILE A 1 57 ? 9.158 56.153 4.136 1.00 16.24 ? 57 ILE A N 1 ATOM 216 C CA . ILE A 1 57 ? 8.143 55.989 5.159 1.00 17.22 ? 57 ILE A CA 1 ATOM 217 C C . ILE A 1 57 ? 8.732 56.080 6.554 1.00 15.98 ? 57 ILE A C 1 ATOM 218 O O . ILE A 1 57 ? 9.877 55.721 6.777 1.00 16.49 ? 57 ILE A O 1 ATOM 219 C CB . ILE A 1 57 ? 7.294 54.708 4.976 1.00 26.26 ? 57 ILE A CB 1 ATOM 220 C CG1 . ILE A 1 57 ? 7.894 53.522 5.706 1.00 24.57 ? 57 ILE A CG1 1 ATOM 221 C CG2 . ILE A 1 57 ? 7.043 54.402 3.512 1.00 30.57 ? 57 ILE A CG2 1 ATOM 222 C CD1 . ILE A 1 57 ? 7.053 52.274 5.604 1.00 30.02 ? 57 ILE A CD1 1 ATOM 223 N N . ASP A 1 58 ? 7.929 56.564 7.489 1.00 17.11 ? 58 ASP A N 1 ATOM 224 C CA . ASP A 1 58 ? 8.323 56.679 8.879 1.00 15.79 ? 58 ASP A CA 1 ATOM 225 C C . ASP A 1 58 ? 8.355 55.278 9.481 1.00 17.14 ? 58 ASP A C 1 ATOM 226 O O . ASP A 1 58 ? 7.314 54.634 9.657 1.00 17.64 ? 58 ASP A O 1 ATOM 227 C CB . ASP A 1 58 ? 7.312 57.533 9.617 1.00 19.71 ? 58 ASP A CB 1 ATOM 228 C CG . ASP A 1 58 ? 7.714 57.837 11.051 1.00 23.37 ? 58 ASP A CG 1 ATOM 229 O OD1 . ASP A 1 58 ? 8.565 57.151 11.644 1.00 20.11 ? 58 ASP A OD1 1 ATOM 230 O OD2 . ASP A 1 58 ? 7.152 58.806 11.626 1.00 30.10 ? 58 ASP A OD2 1 ATOM 231 N N . GLY A 1 59 ? 9.554 54.798 9.782 1.00 14.52 ? 59 GLY A N 1 ATOM 232 C CA . GLY A 1 59 ? 9.705 53.465 10.338 1.00 14.59 ? 59 GLY A CA 1 ATOM 233 C C . GLY A 1 59 ? 9.588 53.378 11.845 1.00 11.77 ? 59 GLY A C 1 ATOM 234 O O . GLY A 1 59 ? 9.764 52.279 12.331 1.00 15.59 ? 59 GLY A O 1 ATOM 235 N N . GLY A 1 60 ? 9.324 54.490 12.524 1.00 13.27 ? 60 GLY A N 1 ATOM 236 C CA . GLY A 1 60 ? 9.258 54.441 13.973 1.00 15.38 ? 60 GLY A CA 1 ATOM 237 C C . GLY A 1 60 ? 10.551 55.018 14.542 1.00 13.08 ? 60 GLY A C 1 ATOM 238 O O . GLY A 1 60 ? 11.078 55.990 13.995 1.00 14.63 ? 60 GLY A O 1 ATOM 239 N N . VAL A 1 61 ? 11.035 54.503 15.670 1.00 12.27 ? 61 VAL A N 1 ATOM 240 C CA . VAL A 1 61 ? 12.254 55.059 16.284 1.00 11.47 ? 61 VAL A CA 1 ATOM 241 C C . VAL A 1 61 ? 13.440 54.911 15.292 1.00 10.37 ? 61 VAL A C 1 ATOM 242 O O . VAL A 1 61 ? 14.271 55.838 15.235 1.00 11.45 ? 61 VAL A O 1 ATOM 243 C CB . VAL A 1 61 ? 12.588 54.453 17.645 1.00 11.36 ? 61 VAL A CB 1 ATOM 244 C CG1 . VAL A 1 61 ? 11.501 54.868 18.660 1.00 15.34 ? 61 VAL A CG1 1 ATOM 245 C CG2 . VAL A 1 61 ? 12.701 52.921 17.579 1.00 13.30 ? 61 VAL A CG2 1 ATOM 246 N N . TRP A 1 62 ? 13.495 53.826 14.556 1.00 9.89 ? 62 TRP A N 1 ATOM 247 C CA . TRP A 1 62 ? 14.404 53.763 13.438 1.00 9.22 ? 62 TRP A CA 1 ATOM 248 C C . TRP A 1 62 ? 13.688 54.429 12.274 1.00 10.14 ? 62 TRP A C 1 ATOM 249 O O . TRP A 1 62 ? 12.929 53.787 11.562 1.00 10.70 ? 62 TRP A O 1 ATOM 250 C CB . TRP A 1 62 ? 14.841 52.316 13.146 1.00 9.27 ? 62 TRP A CB 1 ATOM 251 C CG . TRP A 1 62 ? 15.831 52.204 11.995 1.00 8.55 ? 62 TRP A CG 1 ATOM 252 C CD1 . TRP A 1 62 ? 16.520 53.224 11.402 1.00 8.61 ? 62 TRP A CD1 1 ATOM 253 C CD2 . TRP A 1 62 ? 16.193 51.017 11.292 1.00 9.46 ? 62 TRP A CD2 1 ATOM 254 N NE1 . TRP A 1 62 ? 17.268 52.743 10.377 1.00 8.64 ? 62 TRP A NE1 1 ATOM 255 C CE2 . TRP A 1 62 ? 17.094 51.392 10.284 1.00 9.78 ? 62 TRP A CE2 1 ATOM 256 C CE3 . TRP A 1 62 ? 15.840 49.679 11.408 1.00 8.90 ? 62 TRP A CE3 1 ATOM 257 C CZ2 . TRP A 1 62 ? 17.645 50.479 9.406 1.00 9.33 ? 62 TRP A CZ2 1 ATOM 258 C CZ3 . TRP A 1 62 ? 16.368 48.780 10.539 1.00 9.68 ? 62 TRP A CZ3 1 ATOM 259 C CH2 . TRP A 1 62 ? 17.267 49.179 9.540 1.00 10.37 ? 62 TRP A CH2 1 ATOM 260 N N . LYS A 1 63 ? 13.897 55.737 12.119 1.00 10.51 ? 63 LYS A N 1 ATOM 261 C CA . LYS A 1 63 ? 13.037 56.497 11.191 1.00 10.23 ? 63 LYS A CA 1 ATOM 262 C C . LYS A 1 63 ? 13.037 56.016 9.792 1.00 11.06 ? 63 LYS A C 1 ATOM 263 O O . LYS A 1 63 ? 11.992 56.102 9.088 1.00 12.48 ? 63 LYS A O 1 ATOM 264 C CB . LYS A 1 63 ? 13.411 57.977 11.254 1.00 11.69 ? 63 LYS A CB 1 ATOM 265 C CG . LYS A 1 63 ? 13.008 58.706 12.545 1.00 16.75 ? 63 LYS A CG 1 ATOM 266 C CD . LYS A 1 63 ? 11.643 59.294 12.329 1.00 22.67 ? 63 LYS A CD 1 ATOM 267 C CE . LYS A 1 63 ? 10.954 59.571 13.619 1.00 31.06 ? 63 LYS A CE 1 ATOM 268 N NZ . LYS A 1 63 ? 9.780 58.685 13.541 1.00 26.29 ? 63 LYS A NZ 1 ATOM 269 N N . GLN A 1 64 ? 14.170 55.477 9.324 1.00 10.32 ? 64 GLN A N 1 ATOM 270 C CA . GLN A 1 64 ? 14.262 55.014 7.949 1.00 10.16 ? 64 GLN A CA 1 ATOM 271 C C . GLN A 1 64 ? 14.322 53.514 7.779 1.00 8.78 ? 64 GLN A C 1 ATOM 272 O O . GLN A 1 64 ? 14.622 52.977 6.717 1.00 9.81 ? 64 GLN A O 1 ATOM 273 C CB . GLN A 1 64 ? 15.494 55.670 7.281 1.00 9.30 ? 64 GLN A CB 1 ATOM 274 C CG . GLN A 1 64 ? 15.342 57.148 7.293 1.00 10.52 ? 64 GLN A CG 1 ATOM 275 C CD . GLN A 1 64 ? 16.694 57.848 7.144 1.00 9.66 ? 64 GLN A CD 1 ATOM 276 O OE1 . GLN A 1 64 ? 17.672 57.535 7.882 1.00 10.40 ? 64 GLN A OE1 1 ATOM 277 N NE2 . GLN A 1 64 ? 16.743 58.845 6.218 1.00 10.19 ? 64 GLN A NE2 1 ATOM 278 N N . GLY A 1 65 ? 13.919 52.813 8.868 1.00 10.91 ? 65 GLY A N 1 ATOM 279 C CA . GLY A 1 65 ? 13.885 51.355 8.875 1.00 10.44 ? 65 GLY A CA 1 ATOM 280 C C . GLY A 1 65 ? 12.513 50.814 9.306 1.00 11.89 ? 65 GLY A C 1 ATOM 281 O O . GLY A 1 65 ? 11.487 51.172 8.692 1.00 12.99 ? 65 GLY A O 1 ATOM 282 N N . TRP A 1 66 ? 12.520 49.936 10.298 1.00 12.14 ? 66 TRP A N 1 ATOM 283 C CA . TRP A 1 66 ? 11.277 49.302 10.814 1.00 12.45 ? 66 TRP A CA 1 ATOM 284 C C . TRP A 1 66 ? 11.585 48.919 12.258 1.00 11.21 ? 66 TRP A C 1 ATOM 285 O O . TRP A 1 66 ? 12.702 49.054 12.752 1.00 11.84 ? 66 TRP A O 1 ATOM 286 C CB . TRP A 1 66 ? 10.881 48.071 9.972 1.00 12.11 ? 66 TRP A CB 1 ATOM 287 C CG . TRP A 1 66 ? 11.816 46.946 10.117 1.00 12.55 ? 66 TRP A CG 1 ATOM 288 C CD1 . TRP A 1 66 ? 11.705 45.892 11.005 1.00 11.81 ? 66 TRP A CD1 1 ATOM 289 C CD2 . TRP A 1 66 ? 13.041 46.713 9.403 1.00 12.62 ? 66 TRP A CD2 1 ATOM 290 N NE1 . TRP A 1 66 ? 12.748 45.041 10.884 1.00 12.68 ? 66 TRP A NE1 1 ATOM 291 C CE2 . TRP A 1 66 ? 13.598 45.508 9.905 1.00 11.73 ? 66 TRP A CE2 1 ATOM 292 C CE3 . TRP A 1 66 ? 13.734 47.405 8.366 1.00 11.75 ? 66 TRP A CE3 1 ATOM 293 C CZ2 . TRP A 1 66 ? 14.791 44.970 9.430 1.00 13.45 ? 66 TRP A CZ2 1 ATOM 294 C CZ3 . TRP A 1 66 ? 14.928 46.859 7.888 1.00 13.48 ? 66 TRP A CZ3 1 ATOM 295 C CH2 . TRP A 1 66 ? 15.455 45.652 8.421 1.00 12.49 ? 66 TRP A CH2 1 ATOM 296 N N . ASN A 1 67 ? 10.540 48.488 12.998 1.00 11.87 ? 67 ASN A N 1 ATOM 297 C CA . ASN A 1 67 ? 10.698 48.069 14.403 1.00 11.16 ? 67 ASN A CA 1 ATOM 298 C C . ASN A 1 67 ? 11.293 46.665 14.410 1.00 11.95 ? 67 ASN A C 1 ATOM 299 O O . ASN A 1 67 ? 10.618 45.636 14.118 1.00 13.28 ? 67 ASN A O 1 ATOM 300 C CB . ASN A 1 67 ? 9.309 48.008 15.083 1.00 13.30 ? 67 ASN A CB 1 ATOM 301 C CG . ASN A 1 67 ? 8.757 49.362 15.397 1.00 18.37 ? 67 ASN A CG 1 ATOM 302 O OD1 . ASN A 1 67 ? 9.466 50.378 15.444 1.00 19.31 ? 67 ASN A OD1 1 ATOM 303 N ND2 . ASN A 1 67 ? 7.448 49.406 15.687 1.00 21.83 ? 67 ASN A ND2 1 ATOM 304 N N . ILE A 1 68 ? 12.584 46.570 14.709 1.00 11.43 ? 68 ILE A N 1 ATOM 305 C CA . ILE A 1 68 ? 13.241 45.285 14.649 1.00 11.72 ? 68 ILE A CA 1 ATOM 306 C C . ILE A 1 68 ? 12.801 44.352 15.788 1.00 11.25 ? 68 ILE A C 1 ATOM 307 O O . ILE A 1 68 ? 12.729 44.788 16.916 1.00 12.95 ? 68 ILE A O 1 ATOM 308 C CB . ILE A 1 68 ? 14.811 45.466 14.761 1.00 12.15 ? 68 ILE A CB 1 ATOM 309 C CG1 . ILE A 1 68 ? 15.302 46.357 13.578 1.00 12.95 ? 68 ILE A CG1 1 ATOM 310 C CG2 . ILE A 1 68 ? 15.524 44.120 14.763 1.00 12.38 ? 68 ILE A CG2 1 ATOM 311 C CD1 . ILE A 1 68 ? 16.745 46.837 13.785 1.00 11.05 ? 68 ILE A CD1 1 ATOM 312 N N . LYS A 1 69 ? 12.578 43.099 15.443 1.00 12.56 ? 69 LYS A N 1 ATOM 313 C CA . LYS A 1 69 ? 12.199 42.091 16.453 1.00 14.13 ? 69 LYS A CA 1 ATOM 314 C C . LYS A 1 69 ? 13.259 41.015 16.470 1.00 13.58 ? 69 LYS A C 1 ATOM 315 O O . LYS A 1 69 ? 13.884 40.715 15.460 1.00 15.25 ? 69 LYS A O 1 ATOM 316 C CB . LYS A 1 69 ? 10.809 41.488 16.049 1.00 16.21 ? 69 LYS A CB 1 ATOM 317 C CG . LYS A 1 69 ? 9.659 42.539 16.184 1.00 21.62 ? 69 LYS A CG 1 ATOM 318 C CD . LYS A 1 69 ? 9.327 42.820 17.647 1.00 30.87 ? 69 LYS A CD 1 ATOM 319 C CE . LYS A 1 69 ? 8.263 41.835 18.296 1.00 37.46 ? 69 LYS A CE 1 ATOM 320 N NZ . LYS A 1 69 ? 8.647 40.472 18.912 1.00 33.59 ? 69 LYS A NZ 1 ATOM 321 N N . TYR A 1 70 ? 13.488 40.410 17.655 1.00 13.72 ? 70 TYR A N 1 ATOM 322 C CA . TYR A 1 70 ? 14.445 39.314 17.735 1.00 14.02 ? 70 TYR A CA 1 ATOM 323 C C . TYR A 1 70 ? 13.868 38.262 18.714 1.00 15.40 ? 70 TYR A C 1 ATOM 324 O O . TYR A 1 70 ? 12.998 38.566 19.535 1.00 17.18 ? 70 TYR A O 1 ATOM 325 C CB . TYR A 1 70 ? 15.854 39.813 18.218 1.00 13.50 ? 70 TYR A CB 1 ATOM 326 C CG . TYR A 1 70 ? 15.870 40.454 19.585 1.00 11.25 ? 70 TYR A CG 1 ATOM 327 C CD1 . TYR A 1 70 ? 16.043 39.673 20.771 1.00 13.75 ? 70 TYR A CD1 1 ATOM 328 C CD2 . TYR A 1 70 ? 15.709 41.821 19.744 1.00 14.37 ? 70 TYR A CD2 1 ATOM 329 C CE1 . TYR A 1 70 ? 16.050 40.290 22.009 1.00 13.84 ? 70 TYR A CE1 1 ATOM 330 C CE2 . TYR A 1 70 ? 15.722 42.423 20.972 1.00 14.09 ? 70 TYR A CE2 1 ATOM 331 C CZ . TYR A 1 70 ? 15.884 41.656 22.124 1.00 12.75 ? 70 TYR A CZ 1 ATOM 332 O OH . TYR A 1 70 ? 15.869 42.285 23.336 1.00 15.77 ? 70 TYR A OH 1 ATOM 333 N N . ASP A 1 71 ? 14.353 37.053 18.568 1.00 18.36 ? 71 ASP A N 1 ATOM 334 C CA . ASP A 1 71 ? 13.949 35.948 19.428 1.00 19.01 ? 71 ASP A CA 1 ATOM 335 C C . ASP A 1 71 ? 14.966 35.892 20.562 1.00 21.65 ? 71 ASP A C 1 ATOM 336 O O . ASP A 1 71 ? 16.148 35.625 20.326 1.00 20.52 ? 71 ASP A O 1 ATOM 337 C CB . ASP A 1 71 ? 14.002 34.689 18.602 1.00 21.45 ? 71 ASP A CB 1 ATOM 338 C CG . ASP A 1 71 ? 13.655 33.444 19.415 1.00 25.28 ? 71 ASP A CG 1 ATOM 339 O OD1 . ASP A 1 71 ? 13.404 33.570 20.634 1.00 28.19 ? 71 ASP A OD1 1 ATOM 340 O OD2 . ASP A 1 71 ? 13.655 32.375 18.796 1.00 31.36 ? 71 ASP A OD2 1 ATOM 341 N N . PRO A 1 72 ? 14.537 36.149 21.819 1.00 22.15 ? 72 PRO A N 1 ATOM 342 C CA . PRO A 1 72 ? 15.501 36.107 22.924 1.00 24.33 ? 72 PRO A CA 1 ATOM 343 C C . PRO A 1 72 ? 16.246 34.787 23.077 1.00 23.41 ? 72 PRO A C 1 ATOM 344 O O . PRO A 1 72 ? 17.344 34.751 23.637 1.00 25.39 ? 72 PRO A O 1 ATOM 345 C CB . PRO A 1 72 ? 14.656 36.479 24.154 1.00 27.00 ? 72 PRO A CB 1 ATOM 346 C CG . PRO A 1 72 ? 13.277 36.084 23.759 1.00 29.60 ? 72 PRO A CG 1 ATOM 347 C CD . PRO A 1 72 ? 13.196 36.492 22.309 1.00 25.61 ? 72 PRO A CD 1 ATOM 348 N N . LEU A 1 73 ? 15.679 33.714 22.545 1.00 21.50 ? 73 LEU A N 1 ATOM 349 C CA . LEU A 1 73 ? 16.321 32.407 22.626 1.00 24.93 ? 73 LEU A CA 1 ATOM 350 C C . LEU A 1 73 ? 17.425 32.159 21.584 1.00 21.08 ? 73 LEU A C 1 ATOM 351 O O . LEU A 1 73 ? 18.054 31.115 21.572 1.00 23.23 ? 73 LEU A O 1 ATOM 352 C CB . LEU A 1 73 ? 15.245 31.315 22.505 1.00 22.05 ? 73 LEU A CB 1 ATOM 353 C CG . LEU A 1 73 ? 14.168 31.389 23.595 1.00 28.56 ? 73 LEU A CG 1 ATOM 354 C CD1 . LEU A 1 73 ? 13.092 30.308 23.341 1.00 27.15 ? 73 LEU A CD1 1 ATOM 355 C CD2 . LEU A 1 73 ? 14.837 31.184 24.974 1.00 28.32 ? 73 LEU A CD2 1 ATOM 356 N N . LYS A 1 74 ? 17.663 33.129 20.680 1.00 19.83 ? 74 LYS A N 1 ATOM 357 C CA . LYS A 1 74 ? 18.690 32.919 19.679 1.00 18.39 ? 74 LYS A CA 1 ATOM 358 C C . LYS A 1 74 ? 20.095 32.768 20.286 1.00 16.43 ? 74 LYS A C 1 ATOM 359 O O . LYS A 1 74 ? 20.932 32.027 19.796 1.00 19.93 ? 74 LYS A O 1 ATOM 360 C CB . LYS A 1 74 ? 18.684 34.087 18.678 1.00 18.85 ? 74 LYS A CB 1 ATOM 361 C CG . LYS A 1 74 ? 19.773 33.999 17.618 1.00 20.41 ? 74 LYS A CG 1 ATOM 362 C CD . LYS A 1 74 ? 19.558 35.119 16.564 1.00 20.90 ? 74 LYS A CD 1 ATOM 363 C CE . LYS A 1 74 ? 20.576 34.942 15.437 1.00 23.29 ? 74 LYS A CE 1 ATOM 364 N NZ . LYS A 1 74 ? 20.279 35.913 14.325 1.00 25.99 ? 74 LYS A NZ 1 ATOM 365 N N . TYR A 1 75 ? 20.339 33.498 21.360 1.00 18.72 ? 75 TYR A N 1 ATOM 366 C CA . TYR A 1 75 ? 21.628 33.460 22.035 1.00 17.55 ? 75 TYR A CA 1 ATOM 367 C C . TYR A 1 75 ? 21.423 32.698 23.348 1.00 18.85 ? 75 TYR A C 1 ATOM 368 O O . TYR A 1 75 ? 20.418 32.885 24.001 1.00 22.67 ? 75 TYR A O 1 ATOM 369 C CB . TYR A 1 75 ? 22.192 34.899 22.198 1.00 18.30 ? 75 TYR A CB 1 ATOM 370 C CG . TYR A 1 75 ? 22.528 35.505 20.843 1.00 16.97 ? 75 TYR A CG 1 ATOM 371 C CD1 . TYR A 1 75 ? 23.565 34.999 20.100 1.00 18.27 ? 75 TYR A CD1 1 ATOM 372 C CD2 . TYR A 1 75 ? 21.768 36.529 20.287 1.00 21.38 ? 75 TYR A CD2 1 ATOM 373 C CE1 . TYR A 1 75 ? 23.871 35.486 18.851 1.00 21.83 ? 75 TYR A CE1 1 ATOM 374 C CE2 . TYR A 1 75 ? 22.060 37.035 19.030 1.00 17.73 ? 75 TYR A CE2 1 ATOM 375 C CZ . TYR A 1 75 ? 23.109 36.497 18.319 1.00 20.10 ? 75 TYR A CZ 1 ATOM 376 O OH . TYR A 1 75 ? 23.436 36.970 17.057 1.00 21.74 ? 75 TYR A OH 1 ATOM 377 N N . ASN A 1 76 ? 22.354 31.799 23.664 1.00 17.78 ? 76 ASN A N 1 ATOM 378 C CA . ASN A 1 76 ? 22.235 30.930 24.850 1.00 20.61 ? 76 ASN A CA 1 ATOM 379 C C . ASN A 1 76 ? 23.645 30.621 25.321 1.00 22.01 ? 76 ASN A C 1 ATOM 380 O O . ASN A 1 76 ? 24.630 31.110 24.775 1.00 21.22 ? 76 ASN A O 1 ATOM 381 C CB . ASN A 1 76 ? 21.493 29.626 24.489 1.00 24.77 ? 76 ASN A CB 1 ATOM 382 C CG . ASN A 1 76 ? 22.122 28.904 23.335 1.00 22.27 ? 76 ASN A CG 1 ATOM 383 O OD1 . ASN A 1 76 ? 23.318 28.676 23.309 1.00 24.84 ? 76 ASN A OD1 1 ATOM 384 N ND2 . ASN A 1 76 ? 21.311 28.558 22.338 1.00 31.96 ? 76 ASN A ND2 1 ATOM 385 N N . ALA A 1 77 ? 23.764 29.795 26.360 1.00 24.90 ? 77 ALA A N 1 ATOM 386 C CA . ALA A 1 77 ? 25.094 29.509 26.892 1.00 26.21 ? 77 ALA A CA 1 ATOM 387 C C . ALA A 1 77 ? 26.104 29.016 25.885 1.00 27.33 ? 77 ALA A C 1 ATOM 388 O O . ALA A 1 77 ? 27.290 29.296 26.008 1.00 29.95 ? 77 ALA A O 1 ATOM 389 C CB . ALA A 1 77 ? 24.986 28.490 28.036 1.00 31.75 ? 77 ALA A CB 1 ATOM 390 N N . HIS A 1 78 ? 25.642 28.300 24.872 1.00 28.45 ? 78 HIS A N 1 ATOM 391 C CA . HIS A 1 78 ? 26.591 27.778 23.902 1.00 30.55 ? 78 HIS A CA 1 ATOM 392 C C . HIS A 1 78 ? 26.681 28.578 22.619 1.00 29.80 ? 78 HIS A C 1 ATOM 393 O O . HIS A 1 78 ? 27.307 28.148 21.651 1.00 28.42 ? 78 HIS A O 1 ATOM 394 C CB . HIS A 1 78 ? 26.262 26.308 23.617 1.00 33.69 ? 78 HIS A CB 1 ATOM 395 C CG . HIS A 1 78 ? 26.334 25.456 24.847 1.00 39.84 ? 78 HIS A CG 1 ATOM 396 N ND1 . HIS A 1 78 ? 27.505 25.285 25.561 1.00 41.40 ? 78 HIS A ND1 1 ATOM 397 C CD2 . HIS A 1 78 ? 25.369 24.803 25.542 1.00 40.38 ? 78 HIS A CD2 1 ATOM 398 C CE1 . HIS A 1 78 ? 27.259 24.565 26.642 1.00 39.80 ? 78 HIS A CE1 1 ATOM 399 N NE2 . HIS A 1 78 ? 25.971 24.261 26.656 1.00 42.87 ? 78 HIS A NE2 1 ATOM 400 N N . HIS A 1 79 ? 26.032 29.725 22.602 1.00 25.21 ? 79 HIS A N 1 ATOM 401 C CA . HIS A 1 79 ? 26.091 30.570 21.425 1.00 20.01 ? 79 HIS A CA 1 ATOM 402 C C . HIS A 1 79 ? 25.855 31.999 21.879 1.00 14.58 ? 79 HIS A C 1 ATOM 403 O O . HIS A 1 79 ? 24.743 32.449 21.893 1.00 18.19 ? 79 HIS A O 1 ATOM 404 C CB . HIS A 1 79 ? 25.038 30.108 20.410 1.00 21.09 ? 79 HIS A CB 1 ATOM 405 C CG . HIS A 1 79 ? 24.967 30.936 19.156 1.00 22.14 ? 79 HIS A CG 1 ATOM 406 N ND1 . HIS A 1 79 ? 25.849 30.792 18.109 1.00 26.72 ? 79 HIS A ND1 1 ATOM 407 C CD2 . HIS A 1 79 ? 24.102 31.906 18.783 1.00 23.64 ? 79 HIS A CD2 1 ATOM 408 C CE1 . HIS A 1 79 ? 25.540 31.648 17.151 1.00 21.61 ? 79 HIS A CE1 1 ATOM 409 N NE2 . HIS A 1 79 ? 24.486 32.338 17.538 1.00 22.01 ? 79 HIS A NE2 1 ATOM 410 N N . LYS A 1 80 ? 26.909 32.672 22.319 1.00 15.59 ? 80 LYS A N 1 ATOM 411 C CA . LYS A 1 80 ? 26.724 34.014 22.870 1.00 14.51 ? 80 LYS A CA 1 ATOM 412 C C . LYS A 1 80 ? 26.900 35.070 21.781 1.00 15.08 ? 80 LYS A C 1 ATOM 413 O O . LYS A 1 80 ? 27.461 34.791 20.740 1.00 15.97 ? 80 LYS A O 1 ATOM 414 C CB . LYS A 1 80 ? 27.756 34.292 23.938 1.00 13.62 ? 80 LYS A CB 1 ATOM 415 C CG . LYS A 1 80 ? 27.670 33.250 25.074 1.00 16.42 ? 80 LYS A CG 1 ATOM 416 C CD . LYS A 1 80 ? 28.872 33.324 25.940 1.00 25.10 ? 80 LYS A CD 1 ATOM 417 C CE . LYS A 1 80 ? 28.758 34.483 26.850 1.00 22.73 ? 80 LYS A CE 1 ATOM 418 N NZ . LYS A 1 80 ? 29.565 34.179 28.136 1.00 29.05 ? 80 LYS A NZ 1 ATOM 419 N N . LEU A 1 81 ? 26.379 36.256 22.028 1.00 11.63 ? 81 LEU A N 1 ATOM 420 C CA . LEU A 1 81 ? 26.645 37.401 21.165 1.00 11.04 ? 81 LEU A CA 1 ATOM 421 C C . LEU A 1 81 ? 27.902 38.118 21.647 1.00 11.13 ? 81 LEU A C 1 ATOM 422 O O . LEU A 1 81 ? 27.975 38.575 22.765 1.00 11.09 ? 81 LEU A O 1 ATOM 423 C CB . LEU A 1 81 ? 25.442 38.332 21.193 1.00 12.23 ? 81 LEU A CB 1 ATOM 424 C CG . LEU A 1 81 ? 25.596 39.626 20.388 1.00 11.02 ? 81 LEU A CG 1 ATOM 425 C CD1 . LEU A 1 81 ? 25.696 39.322 18.917 1.00 11.71 ? 81 LEU A CD1 1 ATOM 426 C CD2 . LEU A 1 81 ? 24.448 40.586 20.634 1.00 14.14 ? 81 LEU A CD2 1 ATOM 427 N N . LYS A 1 82 ? 28.904 38.146 20.790 1.00 10.27 ? 82 LYS A N 1 ATOM 428 C CA . LYS A 1 82 ? 30.156 38.800 21.117 1.00 9.94 ? 82 LYS A CA 1 ATOM 429 C C . LYS A 1 82 ? 30.109 40.232 20.600 1.00 10.34 ? 82 LYS A C 1 ATOM 430 O O . LYS A 1 82 ? 29.936 40.444 19.413 1.00 12.24 ? 82 LYS A O 1 ATOM 431 C CB . LYS A 1 82 ? 31.313 38.056 20.449 1.00 11.61 ? 82 LYS A CB 1 ATOM 432 C CG . LYS A 1 82 ? 32.677 38.632 20.763 1.00 22.52 ? 82 LYS A CG 1 ATOM 433 C CD . LYS A 1 82 ? 33.145 38.226 22.147 1.00 29.17 ? 82 LYS A CD 1 ATOM 434 C CE . LYS A 1 82 ? 34.656 38.395 22.309 1.00 35.57 ? 82 LYS A CE 1 ATOM 435 N NZ . LYS A 1 82 ? 35.401 37.237 21.780 1.00 35.50 ? 82 LYS A NZ 1 ATOM 436 N N . VAL A 1 83 ? 30.263 41.198 21.501 1.00 7.26 ? 83 VAL A N 1 ATOM 437 C CA . VAL A 1 83 ? 30.107 42.610 21.147 1.00 8.22 ? 83 VAL A CA 1 ATOM 438 C C . VAL A 1 83 ? 31.432 43.306 21.291 1.00 8.49 ? 83 VAL A C 1 ATOM 439 O O . VAL A 1 83 ? 32.061 43.300 22.389 1.00 9.63 ? 83 VAL A O 1 ATOM 440 C CB . VAL A 1 83 ? 29.068 43.276 22.081 1.00 7.23 ? 83 VAL A CB 1 ATOM 441 C CG1 . VAL A 1 83 ? 28.903 44.789 21.764 1.00 9.14 ? 83 VAL A CG1 1 ATOM 442 C CG2 . VAL A 1 83 ? 27.704 42.568 21.946 1.00 9.40 ? 83 VAL A CG2 1 ATOM 443 N N . PHE A 1 84 ? 31.874 43.999 20.229 1.00 8.55 ? 84 PHE A N 1 ATOM 444 C CA . PHE A 1 84 ? 33.109 44.804 20.280 1.00 9.19 ? 84 PHE A CA 1 ATOM 445 C C . PHE A 1 84 ? 32.764 46.272 20.206 1.00 8.00 ? 84 PHE A C 1 ATOM 446 O O . PHE A 1 84 ? 32.252 46.751 19.185 1.00 8.76 ? 84 PHE A O 1 ATOM 447 C CB . PHE A 1 84 ? 34.010 44.448 19.118 1.00 9.30 ? 84 PHE A CB 1 ATOM 448 C CG . PHE A 1 84 ? 34.636 43.116 19.261 1.00 10.34 ? 84 PHE A CG 1 ATOM 449 C CD1 . PHE A 1 84 ? 35.675 42.935 20.182 1.00 13.63 ? 84 PHE A CD1 1 ATOM 450 C CD2 . PHE A 1 84 ? 34.218 42.061 18.520 1.00 12.20 ? 84 PHE A CD2 1 ATOM 451 C CE1 . PHE A 1 84 ? 36.312 41.653 20.350 1.00 14.24 ? 84 PHE A CE1 1 ATOM 452 C CE2 . PHE A 1 84 ? 34.835 40.776 18.680 1.00 17.56 ? 84 PHE A CE2 1 ATOM 453 C CZ . PHE A 1 84 ? 35.863 40.599 19.576 1.00 16.58 ? 84 PHE A CZ 1 ATOM 454 N N . VAL A 1 85 ? 33.035 46.996 21.284 1.00 7.10 ? 85 VAL A N 1 ATOM 455 C CA . VAL A 1 85 ? 32.817 48.446 21.347 1.00 6.76 ? 85 VAL A CA 1 ATOM 456 C C . VAL A 1 85 ? 34.161 49.063 20.953 1.00 7.00 ? 85 VAL A C 1 ATOM 457 O O . VAL A 1 85 ? 35.184 48.887 21.622 1.00 7.84 ? 85 VAL A O 1 ATOM 458 C CB . VAL A 1 85 ? 32.374 48.860 22.757 1.00 7.91 ? 85 VAL A CB 1 ATOM 459 C CG1 . VAL A 1 85 ? 32.228 50.397 22.844 1.00 10.85 ? 85 VAL A CG1 1 ATOM 460 C CG2 . VAL A 1 85 ? 31.029 48.134 23.086 1.00 9.19 ? 85 VAL A CG2 1 ATOM 461 N N . VAL A 1 86 ? 34.111 49.838 19.841 1.00 6.78 ? 86 VAL A N 1 ATOM 462 C CA . VAL A 1 86 ? 35.354 50.338 19.231 1.00 6.31 ? 86 VAL A CA 1 ATOM 463 C C . VAL A 1 86 ? 35.435 51.850 19.352 1.00 6.62 ? 86 VAL A C 1 ATOM 464 O O . VAL A 1 86 ? 34.760 52.569 18.559 1.00 6.99 ? 86 VAL A O 1 ATOM 465 C CB . VAL A 1 86 ? 35.374 49.895 17.748 1.00 7.07 ? 86 VAL A CB 1 ATOM 466 C CG1 . VAL A 1 86 ? 36.681 50.409 17.050 1.00 9.28 ? 86 VAL A CG1 1 ATOM 467 C CG2 . VAL A 1 86 ? 35.319 48.342 17.654 1.00 9.22 ? 86 VAL A CG2 1 ATOM 468 N N . PRO A 1 87 ? 36.195 52.380 20.299 1.00 6.46 ? 87 PRO A N 1 ATOM 469 C CA . PRO A 1 87 ? 36.315 53.832 20.462 1.00 7.81 ? 87 PRO A CA 1 ATOM 470 C C . PRO A 1 87 ? 37.034 54.452 19.272 1.00 6.43 ? 87 PRO A C 1 ATOM 471 O O . PRO A 1 87 ? 38.052 53.911 18.768 1.00 6.63 ? 87 PRO A O 1 ATOM 472 C CB . PRO A 1 87 ? 37.144 54.007 21.769 1.00 7.22 ? 87 PRO A CB 1 ATOM 473 C CG . PRO A 1 87 ? 36.863 52.660 22.484 1.00 8.41 ? 87 PRO A CG 1 ATOM 474 C CD . PRO A 1 87 ? 36.962 51.666 21.361 1.00 7.74 ? 87 PRO A CD 1 ATOM 475 N N . HIS A 1 88 ? 36.545 55.612 18.844 1.00 5.71 ? 88 HIS A N 1 ATOM 476 C CA . HIS A 1 88 ? 37.130 56.315 17.687 1.00 6.69 ? 88 HIS A CA 1 ATOM 477 C C . HIS A 1 88 ? 36.909 57.824 17.783 1.00 7.13 ? 88 HIS A C 1 ATOM 478 O O . HIS A 1 88 ? 36.119 58.280 18.574 1.00 7.38 ? 88 HIS A O 1 ATOM 479 C CB . HIS A 1 88 ? 36.579 55.753 16.363 1.00 7.70 ? 88 HIS A CB 1 ATOM 480 C CG . HIS A 1 88 ? 35.142 56.079 16.121 1.00 6.39 ? 88 HIS A CG 1 ATOM 481 N ND1 . HIS A 1 88 ? 34.743 57.155 15.363 1.00 6.72 ? 88 HIS A ND1 1 ATOM 482 C CD2 . HIS A 1 88 ? 34.011 55.476 16.559 1.00 7.35 ? 88 HIS A CD2 1 ATOM 483 C CE1 . HIS A 1 88 ? 33.425 57.185 15.321 1.00 8.22 ? 88 HIS A CE1 1 ATOM 484 N NE2 . HIS A 1 88 ? 32.957 56.174 16.032 1.00 8.78 ? 88 HIS A NE2 1 ATOM 485 N N . SER A 1 89 ? 37.625 58.583 16.959 1.00 7.00 ? 89 SER A N 1 ATOM 486 C CA . SER A 1 89 ? 37.544 60.038 16.951 1.00 7.24 ? 89 SER A CA 1 ATOM 487 C C . SER A 1 89 ? 37.705 60.479 15.479 1.00 6.79 ? 89 SER A C 1 ATOM 488 O O . SER A 1 89 ? 38.795 60.305 14.915 1.00 6.95 ? 89 SER A O 1 ATOM 489 C CB . SER A 1 89 ? 38.679 60.608 17.854 1.00 7.34 ? 89 SER A CB 1 ATOM 490 O OG . SER A 1 89 ? 38.660 62.010 17.796 1.00 7.87 ? 89 SER A OG 1 ATOM 491 N N . HIS A 1 90 ? 36.651 61.065 14.903 1.00 6.99 ? 90 HIS A N 1 ATOM 492 C CA . HIS A 1 90 ? 36.750 61.455 13.486 1.00 6.16 ? 90 HIS A CA 1 ATOM 493 C C . HIS A 1 90 ? 37.410 62.836 13.389 1.00 6.58 ? 90 HIS A C 1 ATOM 494 O O . HIS A 1 90 ? 36.862 63.845 13.888 1.00 7.87 ? 90 HIS A O 1 ATOM 495 C CB . HIS A 1 90 ? 35.352 61.427 12.909 1.00 6.80 ? 90 HIS A CB 1 ATOM 496 C CG . HIS A 1 90 ? 35.307 61.791 11.457 1.00 5.81 ? 90 HIS A CG 1 ATOM 497 N ND1 . HIS A 1 90 ? 35.913 61.031 10.473 1.00 7.00 ? 90 HIS A ND1 1 ATOM 498 C CD2 . HIS A 1 90 ? 34.711 62.828 10.829 1.00 6.98 ? 90 HIS A CD2 1 ATOM 499 C CE1 . HIS A 1 90 ? 35.712 61.628 9.296 1.00 6.91 ? 90 HIS A CE1 1 ATOM 500 N NE2 . HIS A 1 90 ? 34.996 62.725 9.469 1.00 6.21 ? 90 HIS A NE2 1 ATOM 501 N N . ASN A 1 91 ? 38.594 62.904 12.788 1.00 7.01 ? 91 ASN A N 1 ATOM 502 C CA . ASN A 1 91 ? 39.395 64.142 12.751 1.00 7.32 ? 91 ASN A CA 1 ATOM 503 C C . ASN A 1 91 ? 39.592 64.642 11.333 1.00 10.05 ? 91 ASN A C 1 ATOM 504 O O . ASN A 1 91 ? 40.432 64.154 10.612 1.00 14.42 ? 91 ASN A O 1 ATOM 505 C CB . ASN A 1 91 ? 40.779 63.889 13.363 1.00 7.97 ? 91 ASN A CB 1 ATOM 506 C CG . ASN A 1 91 ? 40.745 63.871 14.875 1.00 9.00 ? 91 ASN A CG 1 ATOM 507 O OD1 . ASN A 1 91 ? 41.315 64.716 15.523 1.00 10.54 ? 91 ASN A OD1 1 ATOM 508 N ND2 . ASN A 1 91 ? 40.049 62.915 15.432 1.00 6.88 ? 91 ASN A ND2 1 ATOM 509 N N . ASP A 1 92 ? 38.862 65.667 10.964 1.00 6.84 ? 92 ASP A N 1 ATOM 510 C CA . ASP A 1 92 ? 38.979 66.183 9.578 1.00 6.68 ? 92 ASP A CA 1 ATOM 511 C C . ASP A 1 92 ? 40.192 67.023 9.362 1.00 8.07 ? 92 ASP A C 1 ATOM 512 O O . ASP A 1 92 ? 40.394 67.988 10.115 1.00 7.97 ? 92 ASP A O 1 ATOM 513 C CB . ASP A 1 92 ? 37.777 67.114 9.338 1.00 7.05 ? 92 ASP A CB 1 ATOM 514 C CG . ASP A 1 92 ? 36.508 66.356 9.418 1.00 8.25 ? 92 ASP A CG 1 ATOM 515 O OD1 . ASP A 1 92 ? 36.303 65.458 8.610 1.00 7.94 ? 92 ASP A OD1 1 ATOM 516 O OD2 . ASP A 1 92 ? 35.725 66.578 10.387 1.00 8.67 ? 92 ASP A OD2 1 ATOM 517 N N . PRO A 1 93 ? 41.005 66.718 8.337 1.00 6.70 ? 93 PRO A N 1 ATOM 518 C CA . PRO A 1 93 ? 42.207 67.539 8.022 1.00 7.81 ? 93 PRO A CA 1 ATOM 519 C C . PRO A 1 93 ? 41.756 68.803 7.269 1.00 8.51 ? 93 PRO A C 1 ATOM 520 O O . PRO A 1 93 ? 42.073 69.028 6.059 1.00 9.77 ? 93 PRO A O 1 ATOM 521 C CB . PRO A 1 93 ? 43.035 66.627 7.148 1.00 8.37 ? 93 PRO A CB 1 ATOM 522 C CG . PRO A 1 93 ? 42.545 65.196 7.490 1.00 13.17 ? 93 PRO A CG 1 ATOM 523 C CD . PRO A 1 93 ? 41.024 65.403 7.645 1.00 6.83 ? 93 PRO A CD 1 ATOM 524 N N . GLY A 1 94 ? 40.983 69.647 7.970 1.00 7.50 ? 94 GLY A N 1 ATOM 525 C CA . GLY A 1 94 ? 40.379 70.862 7.437 1.00 7.92 ? 94 GLY A CA 1 ATOM 526 C C . GLY A 1 94 ? 38.876 70.632 7.177 1.00 8.15 ? 94 GLY A C 1 ATOM 527 O O . GLY A 1 94 ? 38.451 69.573 6.623 1.00 8.22 ? 94 GLY A O 1 ATOM 528 N N . TRP A 1 95 ? 38.067 71.625 7.589 1.00 7.56 ? 95 TRP A N 1 ATOM 529 C CA . TRP A 1 95 ? 36.648 71.635 7.309 1.00 7.46 ? 95 TRP A CA 1 ATOM 530 C C . TRP A 1 95 ? 36.157 73.049 7.726 1.00 8.80 ? 95 TRP A C 1 ATOM 531 O O . TRP A 1 95 ? 36.094 73.963 6.889 1.00 8.24 ? 95 TRP A O 1 ATOM 532 C CB . TRP A 1 95 ? 35.854 70.513 8.003 1.00 6.85 ? 95 TRP A CB 1 ATOM 533 C CG . TRP A 1 95 ? 34.363 70.687 7.660 1.00 7.18 ? 95 TRP A CG 1 ATOM 534 C CD1 . TRP A 1 95 ? 33.831 71.047 6.428 1.00 7.74 ? 95 TRP A CD1 1 ATOM 535 C CD2 . TRP A 1 95 ? 33.255 70.408 8.508 1.00 7.50 ? 95 TRP A CD2 1 ATOM 536 N NE1 . TRP A 1 95 ? 32.443 71.000 6.495 1.00 8.00 ? 95 TRP A NE1 1 ATOM 537 C CE2 . TRP A 1 95 ? 32.080 70.600 7.753 1.00 7.35 ? 95 TRP A CE2 1 ATOM 538 C CE3 . TRP A 1 95 ? 33.144 69.982 9.853 1.00 9.01 ? 95 TRP A CE3 1 ATOM 539 C CZ2 . TRP A 1 95 ? 30.800 70.384 8.282 1.00 7.63 ? 95 TRP A CZ2 1 ATOM 540 C CZ3 . TRP A 1 95 ? 31.870 69.781 10.381 1.00 9.24 ? 95 TRP A CZ3 1 ATOM 541 C CH2 . TRP A 1 95 ? 30.713 69.982 9.595 1.00 8.41 ? 95 TRP A CH2 1 ATOM 542 N N . ILE A 1 96 ? 35.802 73.226 8.998 1.00 8.12 ? 96 ILE A N 1 ATOM 543 C CA . ILE A 1 96 ? 35.432 74.532 9.572 1.00 9.22 ? 96 ILE A CA 1 ATOM 544 C C . ILE A 1 96 ? 36.646 75.315 10.041 1.00 10.58 ? 96 ILE A C 1 ATOM 545 O O . ILE A 1 96 ? 36.579 76.522 10.184 1.00 12.86 ? 96 ILE A O 1 ATOM 546 C CB . ILE A 1 96 ? 34.543 74.398 10.859 1.00 15.36 ? 96 ILE A CB 1 ATOM 547 C CG1 . ILE A 1 96 ? 33.284 73.601 10.587 1.00 19.37 ? 96 ILE A CG1 1 ATOM 548 C CG2 . ILE A 1 96 ? 34.211 75.778 11.448 1.00 17.25 ? 96 ILE A CG2 1 ATOM 549 C CD1 . ILE A 1 96 ? 32.693 73.980 9.291 1.00 12.63 ? 96 ILE A CD1 1 ATOM 550 N N . GLN A 1 97 ? 37.721 74.590 10.318 1.00 7.62 ? 97 GLN A N 1 ATOM 551 C CA . GLN A 1 97 ? 39.041 75.162 10.653 1.00 7.89 ? 97 GLN A CA 1 ATOM 552 C C . GLN A 1 97 ? 40.069 74.579 9.690 1.00 6.99 ? 97 GLN A C 1 ATOM 553 O O . GLN A 1 97 ? 39.796 73.556 9.032 1.00 7.27 ? 97 GLN A O 1 ATOM 554 C CB . GLN A 1 97 ? 39.472 74.814 12.076 1.00 9.24 ? 97 GLN A CB 1 ATOM 555 C CG . GLN A 1 97 ? 38.472 75.363 13.113 1.00 12.79 ? 97 GLN A CG 1 ATOM 556 C CD . GLN A 1 97 ? 38.944 75.121 14.530 1.00 17.09 ? 97 GLN A CD 1 ATOM 557 O OE1 . GLN A 1 97 ? 40.110 75.338 14.854 1.00 21.95 ? 97 GLN A OE1 1 ATOM 558 N NE2 . GLN A 1 97 ? 38.038 74.631 15.388 1.00 20.40 ? 97 GLN A NE2 1 ATOM 559 N N . THR A 1 98 ? 41.253 75.193 9.553 1.00 7.64 ? 98 THR A N 1 ATOM 560 C CA . THR A 1 98 ? 42.291 74.586 8.717 1.00 7.35 ? 98 THR A CA 1 ATOM 561 C C . THR A 1 98 ? 42.892 73.373 9.441 1.00 7.28 ? 98 THR A C 1 ATOM 562 O O . THR A 1 98 ? 42.679 73.160 10.646 1.00 7.86 ? 98 THR A O 1 ATOM 563 C CB . THR A 1 98 ? 43.423 75.539 8.461 1.00 7.76 ? 98 THR A CB 1 ATOM 564 O OG1 . THR A 1 98 ? 44.022 75.893 9.724 1.00 9.09 ? 98 THR A OG1 1 ATOM 565 C CG2 . THR A 1 98 ? 42.912 76.855 7.813 1.00 8.91 ? 98 THR A CG2 1 ATOM 566 N N . PHE A 1 99 ? 43.666 72.600 8.691 1.00 7.31 ? 99 PHE A N 1 ATOM 567 C CA . PHE A 1 99 ? 44.474 71.532 9.260 1.00 7.38 ? 99 PHE A CA 1 ATOM 568 C C . PHE A 1 99 ? 45.228 72.002 10.502 1.00 7.70 ? 99 PHE A C 1 ATOM 569 O O . PHE A 1 99 ? 45.122 71.405 11.548 1.00 8.00 ? 99 PHE A O 1 ATOM 570 C CB . PHE A 1 99 ? 45.454 70.976 8.210 1.00 8.25 ? 99 PHE A CB 1 ATOM 571 C CG . PHE A 1 99 ? 46.324 69.854 8.732 1.00 8.00 ? 99 PHE A CG 1 ATOM 572 C CD1 . PHE A 1 99 ? 47.556 70.120 9.333 1.00 9.26 ? 99 PHE A CD1 1 ATOM 573 C CD2 . PHE A 1 99 ? 45.899 68.542 8.649 1.00 7.66 ? 99 PHE A CD2 1 ATOM 574 C CE1 . PHE A 1 99 ? 48.320 69.097 9.828 1.00 9.95 ? 99 PHE A CE1 1 ATOM 575 C CE2 . PHE A 1 99 ? 46.674 67.523 9.138 1.00 9.13 ? 99 PHE A CE2 1 ATOM 576 C CZ . PHE A 1 99 ? 47.896 67.796 9.727 1.00 8.39 ? 99 PHE A CZ 1 ATOM 577 N N . GLU A 1 100 ? 45.998 73.077 10.376 1.00 8.04 ? 100 GLU A N 1 ATOM 578 C CA . GLU A 1 100 ? 46.826 73.477 11.503 1.00 8.54 ? 100 GLU A CA 1 ATOM 579 C C . GLU A 1 100 ? 46.010 74.015 12.651 1.00 8.86 ? 100 GLU A C 1 ATOM 580 O O . GLU A 1 100 ? 46.379 73.794 13.815 1.00 9.50 ? 100 GLU A O 1 ATOM 581 C CB . GLU A 1 100 ? 47.878 74.508 11.039 1.00 9.38 ? 100 GLU A CB 1 ATOM 582 C CG . GLU A 1 100 ? 48.897 74.862 12.125 1.00 11.81 ? 100 GLU A CG 1 ATOM 583 C CD . GLU A 1 100 ? 49.773 73.689 12.549 1.00 13.55 ? 100 GLU A CD 1 ATOM 584 O OE1 . GLU A 1 100 ? 49.909 72.669 11.823 1.00 13.41 ? 100 GLU A OE1 1 ATOM 585 O OE2 . GLU A 1 100 ? 50.404 73.837 13.657 1.00 13.22 ? 100 GLU A OE2 1 ATOM 586 N N . GLU A 1 101 ? 44.906 74.679 12.385 1.00 8.56 ? 101 GLU A N 1 ATOM 587 C CA . GLU A 1 101 ? 44.059 75.181 13.457 1.00 8.41 ? 101 GLU A CA 1 ATOM 588 C C . GLU A 1 101 ? 43.475 73.997 14.214 1.00 9.09 ? 101 GLU A C 1 ATOM 589 O O . GLU A 1 101 ? 43.446 73.980 15.459 1.00 9.08 ? 101 GLU A O 1 ATOM 590 C CB . GLU A 1 101 ? 42.940 76.043 12.871 1.00 9.29 ? 101 GLU A CB 1 ATOM 591 C CG . GLU A 1 101 ? 43.405 77.436 12.471 1.00 11.99 ? 101 GLU A CG 1 ATOM 592 C CD . GLU A 1 101 ? 42.404 78.166 11.524 1.00 12.97 ? 101 GLU A CD 1 ATOM 593 O OE1 . GLU A 1 101 ? 41.341 77.654 11.076 1.00 11.66 ? 101 GLU A OE1 1 ATOM 594 O OE2 . GLU A 1 101 ? 42.672 79.386 11.202 1.00 17.83 ? 101 GLU A OE2 1 ATOM 595 N N . TYR A 1 102 ? 42.942 73.008 13.516 1.00 7.53 ? 102 TYR A N 1 ATOM 596 C CA . TYR A 1 102 ? 42.376 71.864 14.224 1.00 7.67 ? 102 TYR A CA 1 ATOM 597 C C . TYR A 1 102 ? 43.483 71.135 15.002 1.00 7.90 ? 102 TYR A C 1 ATOM 598 O O . TYR A 1 102 ? 43.259 70.649 16.095 1.00 8.09 ? 102 TYR A O 1 ATOM 599 C CB . TYR A 1 102 ? 41.757 70.874 13.243 1.00 8.16 ? 102 TYR A CB 1 ATOM 600 C CG . TYR A 1 102 ? 40.317 71.086 12.801 1.00 7.41 ? 102 TYR A CG 1 ATOM 601 C CD1 . TYR A 1 102 ? 39.294 71.324 13.704 1.00 8.18 ? 102 TYR A CD1 1 ATOM 602 C CD2 . TYR A 1 102 ? 39.983 70.941 11.461 1.00 7.85 ? 102 TYR A CD2 1 ATOM 603 C CE1 . TYR A 1 102 ? 37.972 71.454 13.268 1.00 8.02 ? 102 TYR A CE1 1 ATOM 604 C CE2 . TYR A 1 102 ? 38.692 71.058 11.024 1.00 7.51 ? 102 TYR A CE2 1 ATOM 605 C CZ . TYR A 1 102 ? 37.692 71.307 11.928 1.00 7.17 ? 102 TYR A CZ 1 ATOM 606 O OH . TYR A 1 102 ? 36.402 71.422 11.459 1.00 9.51 ? 102 TYR A OH 1 ATOM 607 N N . TYR A 1 103 ? 44.667 71.043 14.418 1.00 7.62 ? 103 TYR A N 1 ATOM 608 C CA . TYR A 1 103 ? 45.729 70.329 15.096 1.00 8.44 ? 103 TYR A CA 1 ATOM 609 C C . TYR A 1 103 ? 46.028 71.018 16.431 1.00 8.58 ? 103 TYR A C 1 ATOM 610 O O . TYR A 1 103 ? 46.129 70.367 17.465 1.00 9.21 ? 103 TYR A O 1 ATOM 611 C CB . TYR A 1 103 ? 46.993 70.245 14.226 1.00 7.90 ? 103 TYR A CB 1 ATOM 612 C CG . TYR A 1 103 ? 48.133 69.616 14.994 1.00 8.51 ? 103 TYR A CG 1 ATOM 613 C CD1 . TYR A 1 103 ? 48.148 68.252 15.264 1.00 9.40 ? 103 TYR A CD1 1 ATOM 614 C CD2 . TYR A 1 103 ? 49.172 70.390 15.495 1.00 9.59 ? 103 TYR A CD2 1 ATOM 615 C CE1 . TYR A 1 103 ? 49.159 67.687 15.987 1.00 10.55 ? 103 TYR A CE1 1 ATOM 616 C CE2 . TYR A 1 103 ? 50.201 69.814 16.227 1.00 9.05 ? 103 TYR A CE2 1 ATOM 617 C CZ . TYR A 1 103 ? 50.175 68.475 16.466 1.00 10.40 ? 103 TYR A CZ 1 ATOM 618 O OH . TYR A 1 103 ? 51.181 67.890 17.195 1.00 12.43 ? 103 TYR A OH 1 ATOM 619 N N . GLN A 1 104 ? 46.143 72.348 16.399 1.00 8.52 ? 104 GLN A N 1 ATOM 620 C CA . GLN A 1 104 ? 46.513 73.066 17.633 1.00 9.05 ? 104 GLN A CA 1 ATOM 621 C C . GLN A 1 104 ? 45.383 73.072 18.623 1.00 10.70 ? 104 GLN A C 1 ATOM 622 O O . GLN A 1 104 ? 45.636 72.970 19.843 1.00 11.81 ? 104 GLN A O 1 ATOM 623 C CB . GLN A 1 104 ? 46.873 74.536 17.280 1.00 12.18 ? 104 GLN A CB 1 ATOM 624 C CG . GLN A 1 104 ? 48.163 74.674 16.549 1.00 12.14 ? 104 GLN A CG 1 ATOM 625 C CD . GLN A 1 104 ? 49.355 74.151 17.330 1.00 13.01 ? 104 GLN A CD 1 ATOM 626 O OE1 . GLN A 1 104 ? 49.351 74.224 18.586 1.00 13.45 ? 104 GLN A OE1 1 ATOM 627 N NE2 . GLN A 1 104 ? 50.368 73.611 16.633 1.00 10.99 ? 104 GLN A NE2 1 ATOM 628 N N . HIS A 1 105 ? 44.114 73.160 18.194 1.00 10.18 ? 105 HIS A N 1 ATOM 629 C CA . HIS A 1 105 ? 42.990 73.323 19.122 1.00 11.21 ? 105 HIS A CA 1 ATOM 630 C C . HIS A 1 105 ? 42.426 72.038 19.611 1.00 11.30 ? 105 HIS A C 1 ATOM 631 O O . HIS A 1 105 ? 41.929 71.982 20.735 1.00 13.82 ? 105 HIS A O 1 ATOM 632 C CB . HIS A 1 105 ? 41.857 74.103 18.429 1.00 12.79 ? 105 HIS A CB 1 ATOM 633 C CG . HIS A 1 105 ? 42.276 75.464 17.938 1.00 16.48 ? 105 HIS A CG 1 ATOM 634 N ND1 . HIS A 1 105 ? 41.705 76.090 16.848 1.00 22.00 ? 105 HIS A ND1 1 ATOM 635 C CD2 . HIS A 1 105 ? 43.235 76.307 18.398 1.00 19.01 ? 105 HIS A CD2 1 ATOM 636 C CE1 . HIS A 1 105 ? 42.305 77.256 16.651 1.00 21.25 ? 105 HIS A CE1 1 ATOM 637 N NE2 . HIS A 1 105 ? 43.236 77.413 17.582 1.00 23.52 ? 105 HIS A NE2 1 ATOM 638 N N . ASP A 1 106 ? 42.522 70.980 18.786 1.00 9.71 ? 106 ASP A N 1 ATOM 639 C CA . ASP A 1 106 ? 41.894 69.723 19.094 1.00 10.79 ? 106 ASP A CA 1 ATOM 640 C C . ASP A 1 106 ? 42.743 68.483 18.969 1.00 9.06 ? 106 ASP A C 1 ATOM 641 O O . ASP A 1 106 ? 42.944 67.763 19.963 1.00 9.78 ? 106 ASP A O 1 ATOM 642 C CB . ASP A 1 106 ? 40.672 69.541 18.155 1.00 12.07 ? 106 ASP A CB 1 ATOM 643 C CG . ASP A 1 106 ? 39.627 70.629 18.355 1.00 20.52 ? 106 ASP A CG 1 ATOM 644 O OD1 . ASP A 1 106 ? 38.841 70.485 19.329 1.00 18.53 ? 106 ASP A OD1 1 ATOM 645 O OD2 . ASP A 1 106 ? 39.617 71.608 17.545 1.00 18.83 ? 106 ASP A OD2 1 ATOM 646 N N . THR A 1 107 ? 43.276 68.216 17.772 1.00 8.61 ? 107 THR A N 1 ATOM 647 C CA . THR A 1 107 ? 43.885 66.908 17.512 1.00 8.47 ? 107 THR A CA 1 ATOM 648 C C . THR A 1 107 ? 45.126 66.635 18.337 1.00 8.11 ? 107 THR A C 1 ATOM 649 O O . THR A 1 107 ? 45.335 65.496 18.778 1.00 7.70 ? 107 THR A O 1 ATOM 650 C CB . THR A 1 107 ? 44.156 66.718 16.001 1.00 7.94 ? 107 THR A CB 1 ATOM 651 O OG1 . THR A 1 107 ? 42.930 66.988 15.323 1.00 8.84 ? 107 THR A OG1 1 ATOM 652 C CG2 . THR A 1 107 ? 44.653 65.332 15.694 1.00 8.31 ? 107 THR A CG2 1 ATOM 653 N N . LYS A 1 108 ? 45.951 67.641 18.561 1.00 8.28 ? 108 LYS A N 1 ATOM 654 C CA . LYS A 1 108 ? 47.122 67.321 19.380 1.00 7.87 ? 108 LYS A CA 1 ATOM 655 C C . LYS A 1 108 ? 46.749 66.925 20.811 1.00 7.20 ? 108 LYS A C 1 ATOM 656 O O . LYS A 1 108 ? 47.453 66.109 21.393 1.00 9.66 ? 108 LYS A O 1 ATOM 657 C CB . LYS A 1 108 ? 48.107 68.506 19.352 1.00 11.15 ? 108 LYS A CB 1 ATOM 658 C CG . LYS A 1 108 ? 47.832 69.661 20.284 1.00 10.42 ? 108 LYS A CG 1 ATOM 659 C CD . LYS A 1 108 ? 48.943 70.720 20.090 1.00 13.54 ? 108 LYS A CD 1 ATOM 660 C CE . LYS A 1 108 ? 48.804 71.859 21.042 1.00 13.43 ? 108 LYS A CE 1 ATOM 661 N NZ . LYS A 1 108 ? 49.950 72.841 20.880 1.00 16.46 ? 108 LYS A NZ 1 ATOM 662 N N . HIS A 1 109 ? 45.653 67.463 21.308 1.00 8.27 ? 109 HIS A N 1 ATOM 663 C CA . HIS A 1 109 ? 45.164 67.094 22.645 1.00 8.75 ? 109 HIS A CA 1 ATOM 664 C C . HIS A 1 109 ? 44.539 65.726 22.630 1.00 8.31 ? 109 HIS A C 1 ATOM 665 O O . HIS A 1 109 ? 44.745 64.949 23.581 1.00 9.73 ? 109 HIS A O 1 ATOM 666 C CB . HIS A 1 109 ? 44.200 68.150 23.139 1.00 10.40 ? 109 HIS A CB 1 ATOM 667 C CG . HIS A 1 109 ? 44.791 69.507 23.147 1.00 13.29 ? 109 HIS A CG 1 ATOM 668 N ND1 . HIS A 1 109 ? 45.811 69.844 24.018 1.00 19.21 ? 109 HIS A ND1 1 ATOM 669 C CD2 . HIS A 1 109 ? 44.576 70.590 22.359 1.00 17.51 ? 109 HIS A CD2 1 ATOM 670 C CE1 . HIS A 1 109 ? 46.189 71.093 23.773 1.00 17.88 ? 109 HIS A CE1 1 ATOM 671 N NE2 . HIS A 1 109 ? 45.459 71.565 22.779 1.00 18.79 ? 109 HIS A NE2 1 ATOM 672 N N . ILE A 1 110 ? 43.780 65.383 21.582 1.00 8.88 ? 110 ILE A N 1 ATOM 673 C CA . ILE A 1 110 ? 43.215 64.048 21.477 1.00 7.67 ? 110 ILE A CA 1 ATOM 674 C C . ILE A 1 110 ? 44.320 62.994 21.460 1.00 7.37 ? 110 ILE A C 1 ATOM 675 O O . ILE A 1 110 ? 44.243 61.978 22.189 1.00 8.09 ? 110 ILE A O 1 ATOM 676 C CB . ILE A 1 110 ? 42.382 63.964 20.176 1.00 8.04 ? 110 ILE A CB 1 ATOM 677 C CG1 . ILE A 1 110 ? 41.173 64.885 20.295 1.00 8.70 ? 110 ILE A CG1 1 ATOM 678 C CG2 . ILE A 1 110 ? 41.998 62.508 19.904 1.00 7.64 ? 110 ILE A CG2 1 ATOM 679 C CD1 . ILE A 1 110 ? 40.439 65.109 18.902 1.00 8.13 ? 110 ILE A CD1 1 ATOM 680 N N . LEU A 1 111 ? 45.354 63.194 20.658 1.00 7.33 ? 111 LEU A N 1 ATOM 681 C CA . LEU A 1 111 ? 46.408 62.192 20.559 1.00 7.41 ? 111 LEU A CA 1 ATOM 682 C C . LEU A 1 111 ? 47.266 62.127 21.829 1.00 6.74 ? 111 LEU A C 1 ATOM 683 O O . LEU A 1 111 ? 47.659 61.063 22.245 1.00 8.89 ? 111 LEU A O 1 ATOM 684 C CB . LEU A 1 111 ? 47.262 62.440 19.306 1.00 7.61 ? 111 LEU A CB 1 ATOM 685 C CG . LEU A 1 111 ? 46.531 62.071 18.001 1.00 8.52 ? 111 LEU A CG 1 ATOM 686 C CD1 . LEU A 1 111 ? 47.319 62.558 16.783 1.00 8.98 ? 111 LEU A CD1 1 ATOM 687 C CD2 . LEU A 1 111 ? 46.318 60.547 17.940 1.00 10.87 ? 111 LEU A CD2 1 ATOM 688 N N . SER A 1 112 ? 47.542 63.271 22.432 1.00 8.29 ? 112 SER A N 1 ATOM 689 C CA . SER A 1 112 ? 48.254 63.274 23.711 1.00 8.69 ? 112 SER A CA 1 ATOM 690 C C . SER A 1 112 ? 47.489 62.543 24.812 1.00 8.81 ? 112 SER A C 1 ATOM 691 O O . SER A 1 112 ? 48.067 61.757 25.546 1.00 9.84 ? 112 SER A O 1 ATOM 692 C CB A SER A 1 112 ? 48.585 64.709 24.134 0.50 10.07 ? 112 SER A CB 1 ATOM 693 C CB B SER A 1 112 ? 48.501 64.689 24.216 0.50 11.16 ? 112 SER A CB 1 ATOM 694 O OG A SER A 1 112 ? 49.406 64.710 25.286 0.50 16.65 ? 112 SER A OG 1 ATOM 695 O OG B SER A 1 112 ? 49.553 65.286 23.518 0.50 27.97 ? 112 SER A OG 1 ATOM 696 N N . ASN A 1 113 ? 46.182 62.789 24.886 1.00 8.94 ? 113 ASN A N 1 ATOM 697 C CA . ASN A 1 113 ? 45.386 62.127 25.910 1.00 9.76 ? 113 ASN A CA 1 ATOM 698 C C . ASN A 1 113 ? 45.137 60.703 25.561 1.00 10.42 ? 113 ASN A C 1 ATOM 699 O O . ASN A 1 113 ? 45.051 59.869 26.503 1.00 10.43 ? 113 ASN A O 1 ATOM 700 C CB . ASN A 1 113 ? 44.123 62.941 26.213 1.00 10.36 ? 113 ASN A CB 1 ATOM 701 C CG . ASN A 1 113 ? 44.527 64.237 26.948 1.00 14.46 ? 113 ASN A CG 1 ATOM 702 O OD1 . ASN A 1 113 ? 45.596 64.258 27.650 1.00 22.15 ? 113 ASN A OD1 1 ATOM 703 N ND2 . ASN A 1 113 ? 43.815 65.304 26.745 1.00 14.66 ? 113 ASN A ND2 1 ATOM 704 N N . ALA A 1 114 ? 45.078 60.333 24.272 1.00 8.73 ? 114 ALA A N 1 ATOM 705 C CA . ALA A 1 114 ? 44.947 58.910 23.934 1.00 8.84 ? 114 ALA A CA 1 ATOM 706 C C . ALA A 1 114 ? 46.210 58.195 24.375 1.00 9.57 ? 114 ALA A C 1 ATOM 707 O O . ALA A 1 114 ? 46.147 57.058 24.902 1.00 10.71 ? 114 ALA A O 1 ATOM 708 C CB . ALA A 1 114 ? 44.754 58.717 22.414 1.00 9.10 ? 114 ALA A CB 1 ATOM 709 N N . LEU A 1 115 ? 47.380 58.773 24.117 1.00 8.80 ? 115 LEU A N 1 ATOM 710 C CA . LEU A 1 115 ? 48.614 58.122 24.532 1.00 10.46 ? 115 LEU A CA 1 ATOM 711 C C . LEU A 1 115 ? 48.640 57.904 26.074 1.00 10.75 ? 115 LEU A C 1 ATOM 712 O O . LEU A 1 115 ? 48.907 56.787 26.538 1.00 11.19 ? 115 LEU A O 1 ATOM 713 C CB . LEU A 1 115 ? 49.806 58.961 24.085 1.00 10.67 ? 115 LEU A CB 1 ATOM 714 C CG . LEU A 1 115 ? 51.190 58.450 24.534 1.00 11.05 ? 115 LEU A CG 1 ATOM 715 C CD1 . LEU A 1 115 ? 51.449 57.009 24.083 1.00 13.32 ? 115 LEU A CD1 1 ATOM 716 C CD2 . LEU A 1 115 ? 52.250 59.358 23.975 1.00 14.17 ? 115 LEU A CD2 1 ATOM 717 N N . ARG A 1 116 ? 48.276 58.946 26.815 1.00 10.44 ? 116 ARG A N 1 ATOM 718 C CA . ARG A 1 116 ? 48.278 58.813 28.270 1.00 10.86 ? 116 ARG A CA 1 ATOM 719 C C . ARG A 1 116 ? 47.227 57.795 28.751 1.00 10.03 ? 116 ARG A C 1 ATOM 720 O O . ARG A 1 116 ? 47.522 56.917 29.573 1.00 11.24 ? 116 ARG A O 1 ATOM 721 C CB . ARG A 1 116 ? 47.993 60.181 28.875 1.00 12.70 ? 116 ARG A CB 1 ATOM 722 C CG . ARG A 1 116 ? 47.739 60.129 30.409 1.00 17.34 ? 116 ARG A CG 1 ATOM 723 C CD . ARG A 1 116 ? 46.777 61.315 30.789 1.00 25.88 ? 116 ARG A CD 1 ATOM 724 N NE . ARG A 1 116 ? 46.339 61.271 32.198 1.00 29.84 ? 116 ARG A NE 1 ATOM 725 C CZ . ARG A 1 116 ? 45.946 62.343 32.885 1.00 31.73 ? 116 ARG A CZ 1 ATOM 726 N NH1 . ARG A 1 116 ? 45.926 63.535 32.298 1.00 27.96 ? 116 ARG A NH1 1 ATOM 727 N NH2 . ARG A 1 116 ? 45.619 62.229 34.169 1.00 34.45 ? 116 ARG A NH2 1 ATOM 728 N N . HIS A 1 117 ? 46.001 57.886 28.247 1.00 9.64 ? 117 HIS A N 1 ATOM 729 C CA . HIS A 1 117 ? 44.924 57.021 28.724 1.00 11.71 ? 117 HIS A CA 1 ATOM 730 C C . HIS A 1 117 ? 45.130 55.562 28.351 1.00 10.57 ? 117 HIS A C 1 ATOM 731 O O . HIS A 1 117 ? 44.899 54.699 29.160 1.00 10.21 ? 117 HIS A O 1 ATOM 732 C CB . HIS A 1 117 ? 43.525 57.516 28.270 1.00 12.08 ? 117 HIS A CB 1 ATOM 733 C CG A HIS A 1 117 ? 43.164 58.595 29.243 0.50 20.15 ? 117 HIS A CG 1 ATOM 734 C CG B HIS A 1 117 ? 42.515 57.173 29.231 0.50 21.12 ? 117 HIS A CG 1 ATOM 735 N ND1 A HIS A 1 117 ? 42.446 58.350 30.393 0.50 16.32 ? 117 HIS A ND1 1 ATOM 736 N ND1 B HIS A 1 117 ? 42.209 57.942 30.334 0.50 26.05 ? 117 HIS A ND1 1 ATOM 737 C CD2 A HIS A 1 117 ? 43.451 59.919 29.249 0.50 21.66 ? 117 HIS A CD2 1 ATOM 738 C CD2 B HIS A 1 117 ? 41.668 56.116 29.257 0.50 12.27 ? 117 HIS A CD2 1 ATOM 739 C CE1 A HIS A 1 117 ? 42.314 59.482 31.065 0.50 23.96 ? 117 HIS A CE1 1 ATOM 740 C CE1 B HIS A 1 117 ? 41.226 57.365 31.002 0.50 19.17 ? 117 HIS A CE1 1 ATOM 741 N NE2 A HIS A 1 117 ? 42.919 60.446 30.399 0.50 21.76 ? 117 HIS A NE2 1 ATOM 742 N NE2 B HIS A 1 117 ? 40.872 56.263 30.364 0.50 27.50 ? 117 HIS A NE2 1 ATOM 743 N N . LEU A 1 118 ? 45.582 55.285 27.131 1.00 9.01 ? 118 LEU A N 1 ATOM 744 C CA . LEU A 1 118 ? 45.810 53.903 26.721 1.00 8.59 ? 118 LEU A CA 1 ATOM 745 C C . LEU A 1 118 ? 47.030 53.386 27.502 1.00 8.47 ? 118 LEU A C 1 ATOM 746 O O . LEU A 1 118 ? 47.025 52.225 27.929 1.00 10.41 ? 118 LEU A O 1 ATOM 747 C CB . LEU A 1 118 ? 46.037 53.803 25.162 1.00 9.06 ? 118 LEU A CB 1 ATOM 748 C CG . LEU A 1 118 ? 44.754 54.266 24.409 1.00 14.63 ? 118 LEU A CG 1 ATOM 749 C CD1 . LEU A 1 118 ? 45.113 54.387 22.893 1.00 14.42 ? 118 LEU A CD1 1 ATOM 750 C CD2 . LEU A 1 118 ? 43.621 53.329 24.574 1.00 16.26 ? 118 LEU A CD2 1 ATOM 751 N N . HIS A 1 119 ? 48.073 54.186 27.647 1.00 9.32 ? 119 HIS A N 1 ATOM 752 C CA . HIS A 1 119 ? 49.249 53.728 28.438 1.00 10.13 ? 119 HIS A CA 1 ATOM 753 C C . HIS A 1 119 ? 48.798 53.310 29.846 1.00 11.48 ? 119 HIS A C 1 ATOM 754 O O . HIS A 1 119 ? 49.124 52.186 30.285 1.00 13.31 ? 119 HIS A O 1 ATOM 755 C CB . HIS A 1 119 ? 50.245 54.888 28.557 1.00 12.14 ? 119 HIS A CB 1 ATOM 756 C CG . HIS A 1 119 ? 51.420 54.594 29.421 1.00 17.51 ? 119 HIS A CG 1 ATOM 757 N ND1 . HIS A 1 119 ? 51.468 54.929 30.760 1.00 20.27 ? 119 HIS A ND1 1 ATOM 758 C CD2 . HIS A 1 119 ? 52.581 53.963 29.139 1.00 17.94 ? 119 HIS A CD2 1 ATOM 759 C CE1 . HIS A 1 119 ? 52.617 54.512 31.268 1.00 23.79 ? 119 HIS A CE1 1 ATOM 760 N NE2 . HIS A 1 119 ? 53.311 53.921 30.309 1.00 21.31 ? 119 HIS A NE2 1 ATOM 761 N N . ASP A 1 120 ? 47.961 54.131 30.470 1.00 10.90 ? 120 ASP A N 1 ATOM 762 C CA . ASP A 1 120 ? 47.555 53.847 31.864 1.00 12.85 ? 120 ASP A CA 1 ATOM 763 C C . ASP A 1 120 ? 46.436 52.854 32.053 1.00 13.56 ? 120 ASP A C 1 ATOM 764 O O . ASP A 1 120 ? 46.220 52.391 33.193 1.00 15.02 ? 120 ASP A O 1 ATOM 765 C CB . ASP A 1 120 ? 47.123 55.174 32.495 1.00 14.10 ? 120 ASP A CB 1 ATOM 766 C CG . ASP A 1 120 ? 48.273 56.121 32.758 1.00 16.49 ? 120 ASP A CG 1 ATOM 767 O OD1 . ASP A 1 120 ? 49.448 55.707 32.671 1.00 18.78 ? 120 ASP A OD1 1 ATOM 768 O OD2 . ASP A 1 120 ? 47.979 57.309 33.050 1.00 24.33 ? 120 ASP A OD2 1 ATOM 769 N N . ASN A 1 121 ? 45.708 52.463 31.010 1.00 12.17 ? 121 ASN A N 1 ATOM 770 C CA . ASN A 1 121 ? 44.535 51.581 31.097 1.00 10.72 ? 121 ASN A CA 1 ATOM 771 C C . ASN A 1 121 ? 44.704 50.544 30.008 1.00 13.29 ? 121 ASN A C 1 ATOM 772 O O . ASN A 1 121 ? 44.188 50.688 28.879 1.00 11.80 ? 121 ASN A O 1 ATOM 773 C CB . ASN A 1 121 ? 43.206 52.362 30.868 1.00 11.95 ? 121 ASN A CB 1 ATOM 774 C CG . ASN A 1 121 ? 43.034 53.447 31.923 1.00 12.06 ? 121 ASN A CG 1 ATOM 775 O OD1 . ASN A 1 121 ? 43.380 54.629 31.720 1.00 15.22 ? 121 ASN A OD1 1 ATOM 776 N ND2 . ASN A 1 121 ? 42.566 53.025 33.132 1.00 12.20 ? 121 ASN A ND2 1 ATOM 777 N N . PRO A 1 122 ? 45.408 49.464 30.306 1.00 11.38 ? 122 PRO A N 1 ATOM 778 C CA . PRO A 1 122 ? 45.701 48.414 29.329 1.00 11.64 ? 122 PRO A CA 1 ATOM 779 C C . PRO A 1 122 ? 44.609 47.777 28.558 1.00 11.46 ? 122 PRO A C 1 ATOM 780 O O . PRO A 1 122 ? 44.819 47.273 27.412 1.00 14.20 ? 122 PRO A O 1 ATOM 781 C CB . PRO A 1 122 ? 46.511 47.383 30.135 1.00 12.83 ? 122 PRO A CB 1 ATOM 782 C CG . PRO A 1 122 ? 47.096 48.209 31.253 1.00 16.33 ? 122 PRO A CG 1 ATOM 783 C CD . PRO A 1 122 ? 45.984 49.154 31.649 1.00 13.66 ? 122 PRO A CD 1 ATOM 784 N N . GLU A 1 123 ? 43.409 47.779 29.132 1.00 12.06 ? 123 GLU A N 1 ATOM 785 C CA . GLU A 1 123 ? 42.256 47.213 28.478 1.00 12.55 ? 123 GLU A CA 1 ATOM 786 C C . GLU A 1 123 ? 41.513 48.162 27.469 1.00 11.21 ? 123 GLU A C 1 ATOM 787 O O . GLU A 1 123 ? 40.662 47.701 26.711 1.00 13.14 ? 123 GLU A O 1 ATOM 788 C CB . GLU A 1 123 ? 41.262 46.787 29.573 1.00 16.39 ? 123 GLU A CB 1 ATOM 789 C CG . GLU A 1 123 ? 40.400 47.928 30.106 1.00 18.42 ? 123 GLU A CG 1 ATOM 790 C CD . GLU A 1 123 ? 41.060 48.952 31.063 1.00 14.75 ? 123 GLU A CD 1 ATOM 791 O OE1 . GLU A 1 123 ? 42.241 48.913 31.397 1.00 16.48 ? 123 GLU A OE1 1 ATOM 792 O OE2 . GLU A 1 123 ? 40.302 49.859 31.544 1.00 22.58 ? 123 GLU A OE2 1 ATOM 793 N N . MET A 1 124 ? 41.835 49.447 27.539 1.00 10.75 ? 124 MET A N 1 ATOM 794 C CA . MET A 1 124 ? 41.193 50.413 26.661 1.00 9.84 ? 124 MET A CA 1 ATOM 795 C C . MET A 1 124 ? 41.799 50.273 25.251 1.00 10.33 ? 124 MET A C 1 ATOM 796 O O . MET A 1 124 ? 42.946 49.949 25.083 1.00 9.32 ? 124 MET A O 1 ATOM 797 C CB . MET A 1 124 ? 41.437 51.813 27.221 1.00 11.01 ? 124 MET A CB 1 ATOM 798 C CG . MET A 1 124 ? 40.644 52.910 26.499 1.00 10.92 ? 124 MET A CG 1 ATOM 799 S SD . MET A 1 124 ? 38.848 52.517 26.471 1.00 11.83 ? 124 MET A SD 1 ATOM 800 C CE . MET A 1 124 ? 38.255 53.981 25.609 1.00 13.27 ? 124 MET A CE 1 ATOM 801 N N . LYS A 1 125 ? 40.969 50.594 24.248 1.00 8.40 ? 125 LYS A N 1 ATOM 802 C CA . LYS A 1 125 ? 41.339 50.486 22.838 1.00 8.51 ? 125 LYS A CA 1 ATOM 803 C C . LYS A 1 125 ? 40.951 51.754 22.125 1.00 10.00 ? 125 LYS A C 1 ATOM 804 O O . LYS A 1 125 ? 40.087 52.533 22.572 1.00 9.49 ? 125 LYS A O 1 ATOM 805 C CB . LYS A 1 125 ? 40.597 49.338 22.182 1.00 10.50 ? 125 LYS A CB 1 ATOM 806 C CG . LYS A 1 125 ? 40.736 47.941 22.825 1.00 15.49 ? 125 LYS A CG 1 ATOM 807 C CD . LYS A 1 125 ? 42.110 47.450 22.567 1.00 17.55 ? 125 LYS A CD 1 ATOM 808 C CE . LYS A 1 125 ? 42.457 46.046 23.167 1.00 27.06 ? 125 LYS A CE 1 ATOM 809 N NZ . LYS A 1 125 ? 41.374 45.129 22.953 1.00 27.33 ? 125 LYS A NZ 1 ATOM 810 N N . PHE A 1 126 ? 41.522 51.978 20.947 1.00 7.81 ? 126 PHE A N 1 ATOM 811 C CA . PHE A 1 126 ? 41.235 53.201 20.148 1.00 7.18 ? 126 PHE A CA 1 ATOM 812 C C . PHE A 1 126 ? 41.669 52.942 18.717 1.00 7.81 ? 126 PHE A C 1 ATOM 813 O O . PHE A 1 126 ? 42.673 52.307 18.488 1.00 8.88 ? 126 PHE A O 1 ATOM 814 C CB . PHE A 1 126 ? 42.054 54.372 20.713 1.00 9.48 ? 126 PHE A CB 1 ATOM 815 C CG . PHE A 1 126 ? 41.653 55.753 20.250 1.00 7.20 ? 126 PHE A CG 1 ATOM 816 C CD1 . PHE A 1 126 ? 40.343 56.199 20.259 1.00 7.76 ? 126 PHE A CD1 1 ATOM 817 C CD2 . PHE A 1 126 ? 42.648 56.661 19.941 1.00 8.74 ? 126 PHE A CD2 1 ATOM 818 C CE1 . PHE A 1 126 ? 40.044 57.510 19.901 1.00 8.76 ? 126 PHE A CE1 1 ATOM 819 C CE2 . PHE A 1 126 ? 42.376 57.943 19.593 1.00 8.74 ? 126 PHE A CE2 1 ATOM 820 C CZ . PHE A 1 126 ? 41.060 58.377 19.568 1.00 8.09 ? 126 PHE A CZ 1 ATOM 821 N N . ILE A 1 127 ? 40.901 53.425 17.752 1.00 6.69 ? 127 ILE A N 1 ATOM 822 C CA . ILE A 1 127 ? 41.361 53.294 16.341 1.00 6.48 ? 127 ILE A CA 1 ATOM 823 C C . ILE A 1 127 ? 41.610 54.718 15.799 1.00 6.59 ? 127 ILE A C 1 ATOM 824 O O . ILE A 1 127 ? 40.995 55.719 16.223 1.00 7.37 ? 127 ILE A O 1 ATOM 825 C CB . ILE A 1 127 ? 40.359 52.574 15.421 1.00 6.50 ? 127 ILE A CB 1 ATOM 826 C CG1 . ILE A 1 127 ? 38.964 53.229 15.428 1.00 7.69 ? 127 ILE A CG1 1 ATOM 827 C CG2 . ILE A 1 127 ? 40.292 51.080 15.830 1.00 7.22 ? 127 ILE A CG2 1 ATOM 828 C CD1 . ILE A 1 127 ? 38.006 52.654 14.321 1.00 9.00 ? 127 ILE A CD1 1 ATOM 829 N N . TRP A 1 128 ? 42.530 54.788 14.827 1.00 6.81 ? 128 TRP A N 1 ATOM 830 C CA . TRP A 1 128 ? 42.959 56.080 14.231 1.00 6.63 ? 128 TRP A CA 1 ATOM 831 C C . TRP A 1 128 ? 43.074 55.921 12.718 1.00 6.50 ? 128 TRP A C 1 ATOM 832 O O . TRP A 1 128 ? 43.737 54.995 12.247 1.00 6.40 ? 128 TRP A O 1 ATOM 833 C CB . TRP A 1 128 ? 44.297 56.529 14.815 1.00 7.13 ? 128 TRP A CB 1 ATOM 834 C CG . TRP A 1 128 ? 44.564 57.977 14.463 1.00 7.00 ? 128 TRP A CG 1 ATOM 835 C CD1 . TRP A 1 128 ? 45.284 58.455 13.370 1.00 6.00 ? 128 TRP A CD1 1 ATOM 836 C CD2 . TRP A 1 128 ? 44.008 59.102 15.114 1.00 6.39 ? 128 TRP A CD2 1 ATOM 837 N NE1 . TRP A 1 128 ? 45.180 59.842 13.331 1.00 7.43 ? 128 TRP A NE1 1 ATOM 838 C CE2 . TRP A 1 128 ? 44.404 60.267 14.390 1.00 6.95 ? 128 TRP A CE2 1 ATOM 839 C CE3 . TRP A 1 128 ? 43.175 59.247 16.274 1.00 7.61 ? 128 TRP A CE3 1 ATOM 840 C CZ2 . TRP A 1 128 ? 44.023 61.548 14.780 1.00 7.39 ? 128 TRP A CZ2 1 ATOM 841 C CZ3 . TRP A 1 128 ? 42.806 60.504 16.639 1.00 7.64 ? 128 TRP A CZ3 1 ATOM 842 C CH2 . TRP A 1 128 ? 43.231 61.655 15.894 1.00 7.19 ? 128 TRP A CH2 1 ATOM 843 N N . ALA A 1 129 ? 42.485 56.882 12.011 1.00 7.14 ? 129 ALA A N 1 ATOM 844 C CA . ALA A 1 129 ? 42.497 56.810 10.541 1.00 7.63 ? 129 ALA A CA 1 ATOM 845 C C . ALA A 1 129 ? 43.398 57.809 9.798 1.00 9.63 ? 129 ALA A C 1 ATOM 846 O O . ALA A 1 129 ? 43.983 57.438 8.782 1.00 9.87 ? 129 ALA A O 1 ATOM 847 C CB . ALA A 1 129 ? 41.087 57.077 10.035 1.00 9.12 ? 129 ALA A CB 1 ATOM 848 N N . GLU A 1 130 ? 43.509 59.046 10.265 1.00 8.82 ? 130 GLU A N 1 ATOM 849 C CA . GLU A 1 130 ? 44.118 60.110 9.447 1.00 8.46 ? 130 GLU A CA 1 ATOM 850 C C . GLU A 1 130 ? 45.622 60.282 9.742 1.00 8.32 ? 130 GLU A C 1 ATOM 851 O O . GLU A 1 130 ? 45.994 60.877 10.728 1.00 8.31 ? 130 GLU A O 1 ATOM 852 C CB . GLU A 1 130 ? 43.369 61.431 9.672 1.00 9.60 ? 130 GLU A CB 1 ATOM 853 C CG . GLU A 1 130 ? 41.842 61.363 9.372 1.00 8.96 ? 130 GLU A CG 1 ATOM 854 C CD . GLU A 1 130 ? 41.000 60.915 10.561 1.00 11.16 ? 130 GLU A CD 1 ATOM 855 O OE1 . GLU A 1 130 ? 41.548 60.709 11.639 1.00 11.22 ? 130 GLU A OE1 1 ATOM 856 O OE2 . GLU A 1 130 ? 39.781 60.805 10.397 1.00 14.42 ? 130 GLU A OE2 1 ATOM 857 N N . ILE A 1 131 ? 46.477 59.755 8.868 1.00 6.58 ? 131 ILE A N 1 ATOM 858 C CA . ILE A 1 131 ? 47.893 59.763 9.171 1.00 6.76 ? 131 ILE A CA 1 ATOM 859 C C . ILE A 1 131 ? 48.503 61.150 8.991 1.00 6.97 ? 131 ILE A C 1 ATOM 860 O O . ILE A 1 131 ? 49.530 61.413 9.644 1.00 7.86 ? 131 ILE A O 1 ATOM 861 C CB . ILE A 1 131 ? 48.614 58.642 8.356 1.00 7.57 ? 131 ILE A CB 1 ATOM 862 C CG1 . ILE A 1 131 ? 47.974 57.285 8.665 1.00 7.96 ? 131 ILE A CG1 1 ATOM 863 C CG2 . ILE A 1 131 ? 50.123 58.619 8.672 1.00 8.71 ? 131 ILE A CG2 1 ATOM 864 C CD1 . ILE A 1 131 ? 47.875 56.947 10.179 1.00 9.85 ? 131 ILE A CD1 1 ATOM 865 N N . SER A 1 132 ? 47.926 62.052 8.205 1.00 5.96 ? 132 SER A N 1 ATOM 866 C CA . SER A 1 132 ? 48.464 63.411 8.159 1.00 6.09 ? 132 SER A CA 1 ATOM 867 C C . SER A 1 132 ? 48.554 63.999 9.589 1.00 7.31 ? 132 SER A C 1 ATOM 868 O O . SER A 1 132 ? 49.613 64.553 9.936 1.00 7.26 ? 132 SER A O 1 ATOM 869 C CB . SER A 1 132 ? 47.546 64.240 7.273 1.00 7.15 ? 132 SER A CB 1 ATOM 870 O OG . SER A 1 132 ? 46.191 64.223 7.721 1.00 7.25 ? 132 SER A OG 1 ATOM 871 N N . TYR A 1 133 ? 47.512 63.825 10.392 1.00 6.04 ? 133 TYR A N 1 ATOM 872 C CA . TYR A 1 133 ? 47.567 64.320 11.769 1.00 6.75 ? 133 TYR A CA 1 ATOM 873 C C . TYR A 1 133 ? 48.514 63.496 12.611 1.00 6.43 ? 133 TYR A C 1 ATOM 874 O O . TYR A 1 133 ? 49.224 64.077 13.492 1.00 8.49 ? 133 TYR A O 1 ATOM 875 C CB . TYR A 1 133 ? 46.205 64.226 12.439 1.00 7.05 ? 133 TYR A CB 1 ATOM 876 C CG . TYR A 1 133 ? 45.287 65.388 12.063 1.00 5.66 ? 133 TYR A CG 1 ATOM 877 C CD1 . TYR A 1 133 ? 45.676 66.707 12.328 1.00 7.29 ? 133 TYR A CD1 1 ATOM 878 C CD2 . TYR A 1 133 ? 44.035 65.160 11.525 1.00 5.86 ? 133 TYR A CD2 1 ATOM 879 C CE1 . TYR A 1 133 ? 44.840 67.819 12.060 1.00 8.71 ? 133 TYR A CE1 1 ATOM 880 C CE2 . TYR A 1 133 ? 43.160 66.226 11.245 1.00 6.85 ? 133 TYR A CE2 1 ATOM 881 C CZ . TYR A 1 133 ? 43.579 67.561 11.510 1.00 8.23 ? 133 TYR A CZ 1 ATOM 882 O OH . TYR A 1 133 ? 42.774 68.655 11.200 1.00 8.37 ? 133 TYR A OH 1 ATOM 883 N N . PHE A 1 134 ? 48.490 62.171 12.483 1.00 6.50 ? 134 PHE A N 1 ATOM 884 C CA . PHE A 1 134 ? 49.311 61.342 13.366 1.00 6.95 ? 134 PHE A CA 1 ATOM 885 C C . PHE A 1 134 ? 50.789 61.645 13.137 1.00 8.60 ? 134 PHE A C 1 ATOM 886 O O . PHE A 1 134 ? 51.586 61.733 14.119 1.00 8.88 ? 134 PHE A O 1 ATOM 887 C CB . PHE A 1 134 ? 49.046 59.882 13.144 1.00 7.05 ? 134 PHE A CB 1 ATOM 888 C CG . PHE A 1 134 ? 49.585 59.027 14.257 1.00 8.68 ? 134 PHE A CG 1 ATOM 889 C CD1 . PHE A 1 134 ? 48.826 58.836 15.440 1.00 8.71 ? 134 PHE A CD1 1 ATOM 890 C CD2 . PHE A 1 134 ? 50.845 58.516 14.153 1.00 10.36 ? 134 PHE A CD2 1 ATOM 891 C CE1 . PHE A 1 134 ? 49.412 58.108 16.520 1.00 9.97 ? 134 PHE A CE1 1 ATOM 892 C CE2 . PHE A 1 134 ? 51.421 57.807 15.222 1.00 11.01 ? 134 PHE A CE2 1 ATOM 893 C CZ . PHE A 1 134 ? 50.691 57.620 16.395 1.00 11.07 ? 134 PHE A CZ 1 ATOM 894 N N . ALA A 1 135 ? 51.197 61.773 11.880 1.00 9.06 ? 135 ALA A N 1 ATOM 895 C CA . ALA A 1 135 ? 52.581 62.143 11.542 1.00 9.19 ? 135 ALA A CA 1 ATOM 896 C C . ALA A 1 135 ? 52.954 63.538 12.103 1.00 9.38 ? 135 ALA A C 1 ATOM 897 O O . ALA A 1 135 ? 54.058 63.730 12.627 1.00 13.41 ? 135 ALA A O 1 ATOM 898 C CB . ALA A 1 135 ? 52.792 62.087 10.034 1.00 10.52 ? 135 ALA A CB 1 ATOM 899 N N . ARG A 1 136 ? 52.038 64.491 12.013 1.00 9.79 ? 136 ARG A N 1 ATOM 900 C CA . ARG A 1 136 ? 52.267 65.876 12.522 1.00 11.41 ? 136 ARG A CA 1 ATOM 901 C C . ARG A 1 136 ? 52.459 65.814 14.057 1.00 14.40 ? 136 ARG A C 1 ATOM 902 O O . ARG A 1 136 ? 53.247 66.616 14.598 1.00 16.74 ? 136 ARG A O 1 ATOM 903 C CB . ARG A 1 136 ? 51.070 66.760 12.218 1.00 12.64 ? 136 ARG A CB 1 ATOM 904 C CG . ARG A 1 136 ? 51.067 68.169 12.914 1.00 14.10 ? 136 ARG A CG 1 ATOM 905 C CD . ARG A 1 136 ? 51.784 69.231 12.037 1.00 14.54 ? 136 ARG A CD 1 ATOM 906 N NE . ARG A 1 136 ? 51.782 70.551 12.690 1.00 14.30 ? 136 ARG A NE 1 ATOM 907 C CZ . ARG A 1 136 ? 52.551 70.810 13.739 1.00 15.05 ? 136 ARG A CZ 1 ATOM 908 N NH1 . ARG A 1 136 ? 53.388 69.856 14.209 1.00 16.70 ? 136 ARG A NH1 1 ATOM 909 N NH2 . ARG A 1 136 ? 52.429 71.992 14.346 1.00 13.29 ? 136 ARG A NH2 1 ATOM 910 N N . PHE A 1 137 ? 51.779 64.894 14.740 1.00 9.97 ? 137 PHE A N 1 ATOM 911 C CA . PHE A 1 137 ? 51.875 64.728 16.195 1.00 9.88 ? 137 PHE A CA 1 ATOM 912 C C . PHE A 1 137 ? 53.153 63.998 16.595 1.00 9.96 ? 137 PHE A C 1 ATOM 913 O O . PHE A 1 137 ? 53.889 64.447 17.463 1.00 12.14 ? 137 PHE A O 1 ATOM 914 C CB . PHE A 1 137 ? 50.671 63.934 16.704 1.00 8.76 ? 137 PHE A CB 1 ATOM 915 C CG . PHE A 1 137 ? 50.669 63.714 18.192 1.00 10.49 ? 137 PHE A CG 1 ATOM 916 C CD1 . PHE A 1 137 ? 50.349 64.741 19.063 1.00 10.99 ? 137 PHE A CD1 1 ATOM 917 C CD2 . PHE A 1 137 ? 50.936 62.468 18.709 1.00 11.01 ? 137 PHE A CD2 1 ATOM 918 C CE1 . PHE A 1 137 ? 50.336 64.539 20.406 1.00 14.25 ? 137 PHE A CE1 1 ATOM 919 C CE2 . PHE A 1 137 ? 50.938 62.264 20.073 1.00 12.69 ? 137 PHE A CE2 1 ATOM 920 C CZ . PHE A 1 137 ? 50.637 63.307 20.913 1.00 11.29 ? 137 PHE A CZ 1 ATOM 921 N N . TYR A 1 138 ? 53.367 62.843 15.984 1.00 10.53 ? 138 TYR A N 1 ATOM 922 C CA . TYR A 1 138 ? 54.473 61.963 16.323 1.00 12.85 ? 138 TYR A CA 1 ATOM 923 C C . TYR A 1 138 ? 55.806 62.645 16.144 1.00 15.29 ? 138 TYR A C 1 ATOM 924 O O . TYR A 1 138 ? 56.691 62.486 17.006 1.00 13.98 ? 138 TYR A O 1 ATOM 925 C CB . TYR A 1 138 ? 54.443 60.682 15.466 1.00 12.94 ? 138 TYR A CB 1 ATOM 926 C CG . TYR A 1 138 ? 55.458 59.659 15.853 1.00 13.72 ? 138 TYR A CG 1 ATOM 927 C CD1 . TYR A 1 138 ? 55.171 58.767 16.869 1.00 13.17 ? 138 TYR A CD1 1 ATOM 928 C CD2 . TYR A 1 138 ? 56.672 59.576 15.178 1.00 14.44 ? 138 TYR A CD2 1 ATOM 929 C CE1 . TYR A 1 138 ? 56.063 57.786 17.228 1.00 15.70 ? 138 TYR A CE1 1 ATOM 930 C CE2 . TYR A 1 138 ? 57.624 58.564 15.539 1.00 12.44 ? 138 TYR A CE2 1 ATOM 931 C CZ . TYR A 1 138 ? 57.268 57.695 16.565 1.00 11.99 ? 138 TYR A CZ 1 ATOM 932 O OH . TYR A 1 138 ? 58.157 56.693 16.940 1.00 16.94 ? 138 TYR A OH 1 ATOM 933 N N . HIS A 1 139 ? 55.976 63.403 15.074 1.00 14.50 ? 139 HIS A N 1 ATOM 934 C CA . HIS A 1 139 ? 57.249 64.054 14.866 1.00 18.70 ? 139 HIS A CA 1 ATOM 935 C C . HIS A 1 139 ? 57.542 65.102 15.941 1.00 22.39 ? 139 HIS A C 1 ATOM 936 O O . HIS A 1 139 ? 58.737 65.385 16.190 1.00 24.24 ? 139 HIS A O 1 ATOM 937 C CB . HIS A 1 139 ? 57.347 64.593 13.429 1.00 18.31 ? 139 HIS A CB 1 ATOM 938 C CG . HIS A 1 139 ? 57.605 63.509 12.405 1.00 22.94 ? 139 HIS A CG 1 ATOM 939 N ND1 . HIS A 1 139 ? 58.737 62.710 12.433 1.00 26.50 ? 139 HIS A ND1 1 ATOM 940 C CD2 . HIS A 1 139 ? 56.905 63.130 11.296 1.00 24.99 ? 139 HIS A CD2 1 ATOM 941 C CE1 . HIS A 1 139 ? 58.730 61.905 11.374 1.00 29.41 ? 139 HIS A CE1 1 ATOM 942 N NE2 . HIS A 1 139 ? 57.639 62.148 10.662 1.00 22.78 ? 139 HIS A NE2 1 ATOM 943 N N . ASP A 1 140 ? 56.520 65.656 16.599 1.00 15.97 ? 140 ASP A N 1 ATOM 944 C CA . ASP A 1 140 ? 56.720 66.650 17.672 1.00 16.85 ? 140 ASP A CA 1 ATOM 945 C C . ASP A 1 140 ? 56.894 66.020 19.070 1.00 13.98 ? 140 ASP A C 1 ATOM 946 O O . ASP A 1 140 ? 57.223 66.734 20.046 1.00 16.60 ? 140 ASP A O 1 ATOM 947 C CB . ASP A 1 140 ? 55.576 67.626 17.738 1.00 18.69 ? 140 ASP A CB 1 ATOM 948 C CG . ASP A 1 140 ? 55.689 68.709 16.665 1.00 23.99 ? 140 ASP A CG 1 ATOM 949 O OD1 . ASP A 1 140 ? 56.554 68.545 15.777 1.00 26.25 ? 140 ASP A OD1 1 ATOM 950 O OD2 . ASP A 1 140 ? 54.931 69.702 16.738 1.00 23.76 ? 140 ASP A OD2 1 ATOM 951 N N . LEU A 1 141 ? 56.727 64.713 19.192 1.00 12.85 ? 141 LEU A N 1 ATOM 952 C CA . LEU A 1 141 ? 56.894 64.028 20.465 1.00 12.56 ? 141 LEU A CA 1 ATOM 953 C C . LEU A 1 141 ? 58.336 63.820 20.829 1.00 13.54 ? 141 LEU A C 1 ATOM 954 O O . LEU A 1 141 ? 59.168 63.552 19.987 1.00 14.79 ? 141 LEU A O 1 ATOM 955 C CB . LEU A 1 141 ? 56.313 62.597 20.409 1.00 14.49 ? 141 LEU A CB 1 ATOM 956 C CG . LEU A 1 141 ? 54.816 62.420 20.485 1.00 16.89 ? 141 LEU A CG 1 ATOM 957 C CD1 . LEU A 1 141 ? 54.518 60.907 20.434 1.00 12.44 ? 141 LEU A CD1 1 ATOM 958 C CD2 . LEU A 1 141 ? 54.249 63.055 21.783 1.00 14.42 ? 141 LEU A CD2 1 ATOM 959 N N . GLY A 1 142 ? 58.618 63.895 22.127 1.00 14.92 ? 142 GLY A N 1 ATOM 960 C CA . GLY A 1 142 ? 59.948 63.559 22.586 1.00 14.77 ? 142 GLY A CA 1 ATOM 961 C C . GLY A 1 142 ? 60.125 62.034 22.471 1.00 14.73 ? 142 GLY A C 1 ATOM 962 O O . GLY A 1 142 ? 59.131 61.266 22.341 1.00 15.77 ? 142 GLY A O 1 ATOM 963 N N . GLU A 1 143 ? 61.368 61.580 22.506 1.00 15.00 ? 143 GLU A N 1 ATOM 964 C CA . GLU A 1 143 ? 61.700 60.174 22.346 1.00 15.67 ? 143 GLU A CA 1 ATOM 965 C C . GLU A 1 143 ? 61.024 59.274 23.382 1.00 14.23 ? 143 GLU A C 1 ATOM 966 O O . GLU A 1 143 ? 60.567 58.178 23.028 1.00 14.38 ? 143 GLU A O 1 ATOM 967 C CB . GLU A 1 143 ? 63.230 59.979 22.358 1.00 19.79 ? 143 GLU A CB 1 ATOM 968 C CG . GLU A 1 143 ? 63.697 58.622 21.856 1.00 21.83 ? 143 GLU A CG 1 ATOM 969 C CD . GLU A 1 143 ? 63.451 58.376 20.342 1.00 27.87 ? 143 GLU A CD 1 ATOM 970 O OE1 . GLU A 1 143 ? 63.185 59.320 19.555 1.00 30.29 ? 143 GLU A OE1 1 ATOM 971 O OE2 . GLU A 1 143 ? 63.556 57.204 19.933 1.00 36.48 ? 143 GLU A OE2 1 ATOM 972 N N . ASN A 1 144 ? 60.919 59.690 24.625 1.00 15.38 ? 144 ASN A N 1 ATOM 973 C CA . ASN A 1 144 ? 60.274 58.826 25.620 1.00 15.44 ? 144 ASN A CA 1 ATOM 974 C C . ASN A 1 144 ? 58.826 58.514 25.210 1.00 15.23 ? 144 ASN A C 1 ATOM 975 O O . ASN A 1 144 ? 58.400 57.367 25.234 1.00 14.52 ? 144 ASN A O 1 ATOM 976 C CB . ASN A 1 144 ? 60.334 59.517 27.008 1.00 17.19 ? 144 ASN A CB 1 ATOM 977 C CG . ASN A 1 144 ? 59.552 58.772 28.090 1.00 28.53 ? 144 ASN A CG 1 ATOM 978 O OD1 . ASN A 1 144 ? 58.301 58.769 28.125 1.00 30.75 ? 144 ASN A OD1 1 ATOM 979 N ND2 . ASN A 1 144 ? 60.293 58.118 28.984 1.00 29.70 ? 144 ASN A ND2 1 ATOM 980 N N . LYS A 1 145 ? 58.108 59.544 24.782 1.00 14.42 ? 145 LYS A N 1 ATOM 981 C CA . LYS A 1 145 ? 56.723 59.390 24.354 1.00 12.64 ? 145 LYS A CA 1 ATOM 982 C C . LYS A 1 145 ? 56.603 58.647 23.016 1.00 11.68 ? 145 LYS A C 1 ATOM 983 O O . LYS A 1 145 ? 55.628 57.920 22.829 1.00 12.95 ? 145 LYS A O 1 ATOM 984 C CB . LYS A 1 145 ? 56.043 60.767 24.293 1.00 15.25 ? 145 LYS A CB 1 ATOM 985 C CG . LYS A 1 145 ? 55.762 61.395 25.723 1.00 17.87 ? 145 LYS A CG 1 ATOM 986 C CD . LYS A 1 145 ? 54.900 60.532 26.639 1.00 26.02 ? 145 LYS A CD 1 ATOM 987 C CE . LYS A 1 145 ? 54.643 61.293 27.976 1.00 29.53 ? 145 LYS A CE 1 ATOM 988 N NZ . LYS A 1 145 ? 55.886 61.823 28.610 1.00 38.04 ? 145 LYS A NZ 1 ATOM 989 N N . LYS A 1 146 ? 57.558 58.852 22.103 1.00 11.95 ? 146 LYS A N 1 ATOM 990 C CA . LYS A 1 146 ? 57.541 58.086 20.838 1.00 11.73 ? 146 LYS A CA 1 ATOM 991 C C . LYS A 1 146 ? 57.599 56.615 21.183 1.00 10.79 ? 146 LYS A C 1 ATOM 992 O O . LYS A 1 146 ? 56.873 55.797 20.601 1.00 12.15 ? 146 LYS A O 1 ATOM 993 C CB . LYS A 1 146 ? 58.743 58.413 19.928 1.00 13.15 ? 146 LYS A CB 1 ATOM 994 C CG . LYS A 1 146 ? 58.655 59.744 19.187 1.00 12.21 ? 146 LYS A CG 1 ATOM 995 C CD . LYS A 1 146 ? 59.835 59.891 18.205 1.00 11.87 ? 146 LYS A CD 1 ATOM 996 C CE A LYS A 1 146 ? 59.680 61.088 17.287 0.50 14.43 ? 146 LYS A CE 1 ATOM 997 C CE B LYS A 1 146 ? 59.742 60.918 17.161 0.50 13.64 ? 146 LYS A CE 1 ATOM 998 N NZ A LYS A 1 146 ? 60.914 61.342 16.495 0.50 29.81 ? 146 LYS A NZ 1 ATOM 999 N NZ B LYS A 1 146 ? 59.914 62.277 17.762 0.50 21.89 ? 146 LYS A NZ 1 ATOM 1000 N N . LEU A 1 147 ? 58.466 56.234 22.129 1.00 13.13 ? 147 LEU A N 1 ATOM 1001 C CA . LEU A 1 147 ? 58.599 54.845 22.534 1.00 12.32 ? 147 LEU A CA 1 ATOM 1002 C C . LEU A 1 147 ? 57.309 54.346 23.218 1.00 11.88 ? 147 LEU A C 1 ATOM 1003 O O . LEU A 1 147 ? 56.867 53.211 22.954 1.00 12.60 ? 147 LEU A O 1 ATOM 1004 C CB . LEU A 1 147 ? 59.804 54.693 23.477 1.00 14.19 ? 147 LEU A CB 1 ATOM 1005 C CG . LEU A 1 147 ? 61.145 54.856 22.760 1.00 16.85 ? 147 LEU A CG 1 ATOM 1006 C CD1 . LEU A 1 147 ? 62.279 54.839 23.786 1.00 21.24 ? 147 LEU A CD1 1 ATOM 1007 C CD2 . LEU A 1 147 ? 61.341 53.700 21.789 1.00 22.50 ? 147 LEU A CD2 1 ATOM 1008 N N . GLN A 1 148 ? 56.684 55.165 24.049 1.00 12.11 ? 148 GLN A N 1 ATOM 1009 C CA . GLN A 1 148 ? 55.407 54.768 24.622 1.00 11.68 ? 148 GLN A CA 1 ATOM 1010 C C . GLN A 1 148 ? 54.329 54.541 23.541 1.00 10.51 ? 148 GLN A C 1 ATOM 1011 O O . GLN A 1 148 ? 53.574 53.597 23.614 1.00 11.46 ? 148 GLN A O 1 ATOM 1012 C CB . GLN A 1 148 ? 54.903 55.790 25.627 1.00 13.02 ? 148 GLN A CB 1 ATOM 1013 C CG . GLN A 1 148 ? 55.690 55.895 26.913 1.00 14.59 ? 148 GLN A CG 1 ATOM 1014 C CD . GLN A 1 148 ? 54.956 56.738 27.921 1.00 20.73 ? 148 GLN A CD 1 ATOM 1015 O OE1 . GLN A 1 148 ? 53.933 57.319 27.613 1.00 27.27 ? 148 GLN A OE1 1 ATOM 1016 N NE2 . GLN A 1 148 ? 55.477 56.800 29.132 1.00 20.87 ? 148 GLN A NE2 1 ATOM 1017 N N . MET A 1 149 ? 54.305 55.409 22.537 1.00 10.65 ? 149 MET A N 1 ATOM 1018 C CA . MET A 1 149 ? 53.330 55.312 21.454 1.00 9.65 ? 149 MET A CA 1 ATOM 1019 C C . MET A 1 149 ? 53.568 54.025 20.651 1.00 9.54 ? 149 MET A C 1 ATOM 1020 O O . MET A 1 149 ? 52.625 53.281 20.316 1.00 10.85 ? 149 MET A O 1 ATOM 1021 C CB . MET A 1 149 ? 53.454 56.541 20.547 1.00 10.59 ? 149 MET A CB 1 ATOM 1022 C CG . MET A 1 149 ? 52.437 56.550 19.396 1.00 10.88 ? 149 MET A CG 1 ATOM 1023 S SD . MET A 1 149 ? 50.764 56.757 19.988 1.00 13.77 ? 149 MET A SD 1 ATOM 1024 C CE . MET A 1 149 ? 50.626 58.505 20.133 1.00 20.83 ? 149 MET A CE 1 ATOM 1025 N N . LYS A 1 150 ? 54.842 53.752 20.327 1.00 10.53 ? 150 LYS A N 1 ATOM 1026 C CA . LYS A 1 150 ? 55.128 52.546 19.572 1.00 12.18 ? 150 LYS A CA 1 ATOM 1027 C C . LYS A 1 150 ? 54.663 51.305 20.363 1.00 11.19 ? 150 LYS A C 1 ATOM 1028 O O . LYS A 1 150 ? 54.178 50.323 19.782 1.00 13.43 ? 150 LYS A O 1 ATOM 1029 C CB . LYS A 1 150 ? 56.637 52.464 19.241 1.00 12.36 ? 150 LYS A CB 1 ATOM 1030 C CG . LYS A 1 150 ? 57.089 53.394 18.167 1.00 14.72 ? 150 LYS A CG 1 ATOM 1031 C CD . LYS A 1 150 ? 58.627 53.373 17.930 1.00 19.63 ? 150 LYS A CD 1 ATOM 1032 C CE . LYS A 1 150 ? 59.070 52.019 17.446 1.00 30.89 ? 150 LYS A CE 1 ATOM 1033 N NZ . LYS A 1 150 ? 60.093 52.219 16.379 1.00 36.84 ? 150 LYS A NZ 1 ATOM 1034 N N . SER A 1 151 ? 54.783 51.334 21.690 1.00 11.66 ? 151 SER A N 1 ATOM 1035 C CA . SER A 1 151 ? 54.398 50.202 22.507 1.00 12.85 ? 151 SER A CA 1 ATOM 1036 C C . SER A 1 151 ? 52.865 49.973 22.530 1.00 10.06 ? 151 SER A C 1 ATOM 1037 O O . SER A 1 151 ? 52.414 48.828 22.503 1.00 11.93 ? 151 SER A O 1 ATOM 1038 C CB . SER A 1 151 ? 54.968 50.368 23.932 1.00 14.58 ? 151 SER A CB 1 ATOM 1039 O OG A SER A 1 151 ? 54.170 51.230 24.721 0.50 29.04 ? 151 SER A OG 1 ATOM 1040 O OG B SER A 1 151 ? 54.665 49.204 24.664 0.50 20.95 ? 151 SER A OG 1 ATOM 1041 N N . ILE A 1 152 ? 52.057 51.034 22.598 1.00 10.19 ? 152 ILE A N 1 ATOM 1042 C CA . ILE A 1 152 ? 50.622 50.818 22.581 1.00 9.70 ? 152 ILE A CA 1 ATOM 1043 C C . ILE A 1 152 ? 50.108 50.425 21.192 1.00 9.19 ? 152 ILE A C 1 ATOM 1044 O O . ILE A 1 152 ? 49.042 49.837 21.103 1.00 10.95 ? 152 ILE A O 1 ATOM 1045 C CB . ILE A 1 152 ? 49.776 52.002 23.158 1.00 11.27 ? 152 ILE A CB 1 ATOM 1046 C CG1 . ILE A 1 152 ? 50.011 53.300 22.402 1.00 11.06 ? 152 ILE A CG1 1 ATOM 1047 C CG2 . ILE A 1 152 ? 50.064 52.144 24.690 1.00 12.03 ? 152 ILE A CG2 1 ATOM 1048 C CD1 . ILE A 1 152 ? 48.947 54.405 22.740 1.00 11.76 ? 152 ILE A CD1 1 ATOM 1049 N N . VAL A 1 153 ? 50.879 50.712 20.130 1.00 10.07 ? 153 VAL A N 1 ATOM 1050 C CA . VAL A 1 153 ? 50.515 50.212 18.789 1.00 9.73 ? 153 VAL A CA 1 ATOM 1051 C C . VAL A 1 153 ? 50.951 48.748 18.697 1.00 11.47 ? 153 VAL A C 1 ATOM 1052 O O . VAL A 1 153 ? 50.167 47.862 18.270 1.00 11.91 ? 153 VAL A O 1 ATOM 1053 C CB . VAL A 1 153 ? 51.195 51.084 17.735 1.00 9.47 ? 153 VAL A CB 1 ATOM 1054 C CG1 . VAL A 1 153 ? 51.086 50.408 16.343 1.00 12.12 ? 153 VAL A CG1 1 ATOM 1055 C CG2 . VAL A 1 153 ? 50.598 52.474 17.769 1.00 10.12 ? 153 VAL A CG2 1 ATOM 1056 N N . LYS A 1 154 ? 52.159 48.452 19.151 1.00 12.37 ? 154 LYS A N 1 ATOM 1057 C CA . LYS A 1 154 ? 52.668 47.092 19.062 1.00 14.29 ? 154 LYS A CA 1 ATOM 1058 C C . LYS A 1 154 ? 51.797 46.086 19.815 1.00 14.87 ? 154 LYS A C 1 ATOM 1059 O O . LYS A 1 154 ? 51.605 44.968 19.350 1.00 16.80 ? 154 LYS A O 1 ATOM 1060 C CB . LYS A 1 154 ? 54.113 47.034 19.556 1.00 14.14 ? 154 LYS A CB 1 ATOM 1061 C CG . LYS A 1 154 ? 54.789 45.696 19.337 1.00 22.12 ? 154 LYS A CG 1 ATOM 1062 C CD . LYS A 1 154 ? 56.280 45.799 19.607 1.00 23.84 ? 154 LYS A CD 1 ATOM 1063 C CE . LYS A 1 154 ? 57.000 44.558 19.122 1.00 29.58 ? 154 LYS A CE 1 ATOM 1064 N NZ . LYS A 1 154 ? 57.549 44.741 17.751 1.00 32.07 ? 154 LYS A NZ 1 ATOM 1065 N N . ASN A 1 155 ? 51.241 46.491 20.951 1.00 13.15 ? 155 ASN A N 1 ATOM 1066 C CA . ASN A 1 155 ? 50.485 45.595 21.819 1.00 13.99 ? 155 ASN A CA 1 ATOM 1067 C C . ASN A 1 155 ? 48.971 45.608 21.551 1.00 15.22 ? 155 ASN A C 1 ATOM 1068 O O . ASN A 1 155 ? 48.207 44.974 22.258 1.00 16.93 ? 155 ASN A O 1 ATOM 1069 C CB A ASN A 1 155 ? 50.528 45.976 23.370 0.50 21.47 ? 155 ASN A CB 1 ATOM 1070 C CB B ASN A 1 155 ? 51.170 45.845 23.167 0.50 23.69 ? 155 ASN A CB 1 ATOM 1071 C CG A ASN A 1 155 ? 49.866 47.325 23.713 0.50 23.45 ? 155 ASN A CG 1 ATOM 1072 C CG B ASN A 1 155 ? 52.594 45.273 23.226 0.50 26.46 ? 155 ASN A CG 1 ATOM 1073 O OD1 A ASN A 1 155 ? 49.337 48.004 22.843 0.50 24.45 ? 155 ASN A OD1 1 ATOM 1074 O OD1 B ASN A 1 155 ? 52.933 44.354 22.480 0.50 28.54 ? 155 ASN A OD1 1 ATOM 1075 N ND2 A ASN A 1 155 ? 49.918 47.714 24.988 0.50 17.91 ? 155 ASN A ND2 1 ATOM 1076 N ND2 B ASN A 1 155 ? 53.430 45.819 24.116 0.50 27.66 ? 155 ASN A ND2 1 ATOM 1077 N N . GLY A 1 156 ? 48.563 46.339 20.536 1.00 12.94 ? 156 GLY A N 1 ATOM 1078 C CA . GLY A 1 156 ? 47.224 46.195 19.992 1.00 13.74 ? 156 GLY A CA 1 ATOM 1079 C C . GLY A 1 156 ? 46.191 47.156 20.558 1.00 12.90 ? 156 GLY A C 1 ATOM 1080 O O . GLY A 1 156 ? 45.030 47.096 20.182 1.00 14.90 ? 156 GLY A O 1 ATOM 1081 N N . GLN A 1 157 ? 46.606 48.046 21.450 1.00 9.64 ? 157 GLN A N 1 ATOM 1082 C CA . GLN A 1 157 ? 45.694 48.996 22.076 1.00 10.02 ? 157 GLN A CA 1 ATOM 1083 C C . GLN A 1 157 ? 45.265 50.079 21.092 1.00 8.94 ? 157 GLN A C 1 ATOM 1084 O O . GLN A 1 157 ? 44.073 50.302 20.880 1.00 9.33 ? 157 GLN A O 1 ATOM 1085 C CB . GLN A 1 157 ? 46.344 49.631 23.307 1.00 9.02 ? 157 GLN A CB 1 ATOM 1086 C CG . GLN A 1 157 ? 46.262 48.777 24.562 1.00 9.67 ? 157 GLN A CG 1 ATOM 1087 C CD . GLN A 1 157 ? 46.629 49.547 25.815 1.00 8.53 ? 157 GLN A CD 1 ATOM 1088 O OE1 . GLN A 1 157 ? 47.781 49.537 26.250 1.00 12.27 ? 157 GLN A OE1 1 ATOM 1089 N NE2 . GLN A 1 157 ? 45.648 50.222 26.404 1.00 8.43 ? 157 GLN A NE2 1 ATOM 1090 N N . LEU A 1 158 ? 46.219 50.753 20.453 1.00 8.93 ? 158 LEU A N 1 ATOM 1091 C CA . LEU A 1 158 ? 45.947 51.739 19.389 1.00 8.43 ? 158 LEU A CA 1 ATOM 1092 C C . LEU A 1 158 ? 46.165 51.073 18.054 1.00 9.63 ? 158 LEU A C 1 ATOM 1093 O O . LEU A 1 158 ? 47.223 50.562 17.757 1.00 10.09 ? 158 LEU A O 1 ATOM 1094 C CB A LEU A 1 158 ? 46.886 52.939 19.545 0.50 9.27 ? 158 LEU A CB 1 ATOM 1095 C CB B LEU A 1 158 ? 46.883 52.913 19.595 0.50 9.45 ? 158 LEU A CB 1 ATOM 1096 C CG A LEU A 1 158 ? 46.789 54.190 18.658 0.50 15.88 ? 158 LEU A CG 1 ATOM 1097 C CG B LEU A 1 158 ? 46.938 53.939 18.474 0.50 16.65 ? 158 LEU A CG 1 ATOM 1098 C CD1 A LEU A 1 158 ? 48.065 55.004 18.853 0.50 15.72 ? 158 LEU A CD1 1 ATOM 1099 C CD1 B LEU A 1 158 ? 45.629 54.593 18.365 0.50 16.15 ? 158 LEU A CD1 1 ATOM 1100 C CD2 A LEU A 1 158 ? 46.672 53.905 17.217 0.50 21.77 ? 158 LEU A CD2 1 ATOM 1101 C CD2 B LEU A 1 158 ? 48.065 54.951 18.742 0.50 15.81 ? 158 LEU A CD2 1 ATOM 1102 N N . GLU A 1 159 ? 45.114 51.062 17.260 1.00 7.94 ? 159 GLU A N 1 ATOM 1103 C CA . GLU A 1 159 ? 45.141 50.392 15.966 1.00 8.48 ? 159 GLU A CA 1 ATOM 1104 C C . GLU A 1 159 ? 44.841 51.368 14.833 1.00 7.41 ? 159 GLU A C 1 ATOM 1105 O O . GLU A 1 159 ? 43.910 52.169 14.921 1.00 8.47 ? 159 GLU A O 1 ATOM 1106 C CB . GLU A 1 159 ? 44.140 49.235 15.941 1.00 10.59 ? 159 GLU A CB 1 ATOM 1107 C CG . GLU A 1 159 ? 44.061 48.512 14.606 1.00 10.82 ? 159 GLU A CG 1 ATOM 1108 C CD . GLU A 1 159 ? 43.077 47.358 14.626 1.00 12.82 ? 159 GLU A CD 1 ATOM 1109 O OE1 . GLU A 1 159 ? 43.370 46.337 15.284 1.00 13.71 ? 159 GLU A OE1 1 ATOM 1110 O OE2 . GLU A 1 159 ? 42.012 47.471 13.984 1.00 11.18 ? 159 GLU A OE2 1 ATOM 1111 N N . PHE A 1 160 ? 45.636 51.297 13.771 1.00 7.43 ? 160 PHE A N 1 ATOM 1112 C CA . PHE A 1 160 ? 45.463 52.179 12.623 1.00 7.52 ? 160 PHE A CA 1 ATOM 1113 C C . PHE A 1 160 ? 44.540 51.555 11.582 1.00 6.74 ? 160 PHE A C 1 ATOM 1114 O O . PHE A 1 160 ? 44.741 50.415 11.164 1.00 7.82 ? 160 PHE A O 1 ATOM 1115 C CB . PHE A 1 160 ? 46.817 52.512 11.994 1.00 7.14 ? 160 PHE A CB 1 ATOM 1116 C CG . PHE A 1 160 ? 47.685 53.387 12.851 1.00 7.30 ? 160 PHE A CG 1 ATOM 1117 C CD1 . PHE A 1 160 ? 47.409 54.737 12.990 1.00 7.65 ? 160 PHE A CD1 1 ATOM 1118 C CD2 . PHE A 1 160 ? 48.778 52.860 13.520 1.00 8.33 ? 160 PHE A CD2 1 ATOM 1119 C CE1 . PHE A 1 160 ? 48.206 55.545 13.778 1.00 8.87 ? 160 PHE A CE1 1 ATOM 1120 C CE2 . PHE A 1 160 ? 49.579 53.663 14.310 1.00 9.69 ? 160 PHE A CE2 1 ATOM 1121 C CZ . PHE A 1 160 ? 49.292 55.007 14.439 1.00 10.23 ? 160 PHE A CZ 1 ATOM 1122 N N . VAL A 1 161 ? 43.528 52.310 11.167 1.00 6.40 ? 161 VAL A N 1 ATOM 1123 C CA . VAL A 1 161 ? 42.525 51.804 10.237 1.00 6.86 ? 161 VAL A CA 1 ATOM 1124 C C . VAL A 1 161 ? 42.732 52.625 8.953 1.00 6.99 ? 161 VAL A C 1 ATOM 1125 O O . VAL A 1 161 ? 42.845 53.873 8.968 1.00 8.16 ? 161 VAL A O 1 ATOM 1126 C CB . VAL A 1 161 ? 41.063 51.884 10.800 1.00 5.85 ? 161 VAL A CB 1 ATOM 1127 C CG1 . VAL A 1 161 ? 40.945 50.911 11.973 1.00 7.69 ? 161 VAL A CG1 1 ATOM 1128 C CG2 . VAL A 1 161 ? 40.748 53.270 11.282 1.00 8.56 ? 161 VAL A CG2 1 ATOM 1129 N N . THR A 1 162 ? 42.728 51.894 7.835 1.00 6.73 ? 162 THR A N 1 ATOM 1130 C CA . THR A 1 162 ? 43.126 52.376 6.500 1.00 7.77 ? 162 THR A CA 1 ATOM 1131 C C . THR A 1 162 ? 44.592 52.832 6.415 1.00 6.16 ? 162 THR A C 1 ATOM 1132 O O . THR A 1 162 ? 45.371 52.272 5.674 1.00 8.51 ? 162 THR A O 1 ATOM 1133 C CB . THR A 1 162 ? 42.228 53.520 5.950 1.00 8.13 ? 162 THR A CB 1 ATOM 1134 O OG1 . THR A 1 162 ? 40.853 53.150 6.077 1.00 9.27 ? 162 THR A OG1 1 ATOM 1135 C CG2 . THR A 1 162 ? 42.534 53.774 4.434 1.00 10.00 ? 162 THR A CG2 1 ATOM 1136 N N . GLY A 1 163 ? 44.933 53.865 7.172 1.00 7.26 ? 163 GLY A N 1 ATOM 1137 C CA . GLY A 1 163 ? 46.328 54.302 7.204 1.00 7.43 ? 163 GLY A CA 1 ATOM 1138 C C . GLY A 1 163 ? 46.662 55.246 6.055 1.00 6.09 ? 163 GLY A C 1 ATOM 1139 O O . GLY A 1 163 ? 47.813 55.447 5.739 1.00 7.42 ? 163 GLY A O 1 ATOM 1140 N N . GLY A 1 164 ? 45.621 55.812 5.415 1.00 6.60 ? 164 GLY A N 1 ATOM 1141 C CA . GLY A 1 164 ? 45.915 56.854 4.412 1.00 6.83 ? 164 GLY A CA 1 ATOM 1142 C C . GLY A 1 164 ? 46.243 58.193 5.024 1.00 6.22 ? 164 GLY A C 1 ATOM 1143 O O . GLY A 1 164 ? 45.978 58.477 6.226 1.00 6.48 ? 164 GLY A O 1 ATOM 1144 N N . TRP A 1 165 ? 46.816 59.109 4.232 1.00 5.40 ? 165 TRP A N 1 ATOM 1145 C CA . TRP A 1 165 ? 47.082 60.482 4.718 1.00 5.71 ? 165 TRP A CA 1 ATOM 1146 C C . TRP A 1 165 ? 45.779 61.089 5.184 1.00 5.00 ? 165 TRP A C 1 ATOM 1147 O O . TRP A 1 165 ? 45.747 61.840 6.194 1.00 6.20 ? 165 TRP A O 1 ATOM 1148 C CB . TRP A 1 165 ? 47.718 61.283 3.553 1.00 5.77 ? 165 TRP A CB 1 ATOM 1149 C CG . TRP A 1 165 ? 48.538 62.430 4.031 1.00 5.71 ? 165 TRP A CG 1 ATOM 1150 C CD1 . TRP A 1 165 ? 48.351 63.756 3.709 1.00 8.29 ? 165 TRP A CD1 1 ATOM 1151 C CD2 . TRP A 1 165 ? 49.738 62.344 4.820 1.00 6.72 ? 165 TRP A CD2 1 ATOM 1152 N NE1 . TRP A 1 165 ? 49.377 64.500 4.285 1.00 8.79 ? 165 TRP A NE1 1 ATOM 1153 C CE2 . TRP A 1 165 ? 50.226 63.670 4.961 1.00 7.67 ? 165 TRP A CE2 1 ATOM 1154 C CE3 . TRP A 1 165 ? 50.443 61.275 5.404 1.00 9.28 ? 165 TRP A CE3 1 ATOM 1155 C CZ2 . TRP A 1 165 ? 51.426 63.972 5.727 1.00 9.83 ? 165 TRP A CZ2 1 ATOM 1156 C CZ3 . TRP A 1 165 ? 51.669 61.608 6.157 1.00 11.09 ? 165 TRP A CZ3 1 ATOM 1157 C CH2 . TRP A 1 165 ? 52.084 62.929 6.279 1.00 11.64 ? 165 TRP A CH2 1 ATOM 1158 N N . VAL A 1 166 ? 44.691 60.796 4.476 1.00 5.53 ? 166 VAL A N 1 ATOM 1159 C CA . VAL A 1 166 ? 43.351 61.294 4.798 1.00 5.82 ? 166 VAL A CA 1 ATOM 1160 C C . VAL A 1 166 ? 42.308 60.160 4.658 1.00 5.60 ? 166 VAL A C 1 ATOM 1161 O O . VAL A 1 166 ? 42.642 59.058 4.314 1.00 6.62 ? 166 VAL A O 1 ATOM 1162 C CB . VAL A 1 166 ? 42.952 62.481 3.850 1.00 5.98 ? 166 VAL A CB 1 ATOM 1163 C CG1 . VAL A 1 166 ? 43.944 63.633 3.951 1.00 6.65 ? 166 VAL A CG1 1 ATOM 1164 C CG2 . VAL A 1 166 ? 42.882 62.006 2.408 1.00 7.68 ? 166 VAL A CG2 1 ATOM 1165 N N . MET A 1 167 ? 41.062 60.459 4.934 1.00 6.13 ? 167 MET A N 1 ATOM 1166 C CA . MET A 1 167 ? 39.961 59.607 4.529 1.00 5.46 ? 167 MET A CA 1 ATOM 1167 C C . MET A 1 167 ? 39.313 60.298 3.321 1.00 7.13 ? 167 MET A C 1 ATOM 1168 O O . MET A 1 167 ? 38.602 61.266 3.465 1.00 6.99 ? 167 MET A O 1 ATOM 1169 C CB . MET A 1 167 ? 38.989 59.536 5.700 1.00 6.74 ? 167 MET A CB 1 ATOM 1170 C CG . MET A 1 167 ? 37.686 58.771 5.427 1.00 6.07 ? 167 MET A CG 1 ATOM 1171 S SD . MET A 1 167 ? 36.484 58.863 6.811 1.00 8.00 ? 167 MET A SD 1 ATOM 1172 C CE . MET A 1 167 ? 37.420 58.082 8.142 1.00 8.66 ? 167 MET A CE 1 ATOM 1173 N N . PRO A 1 168 ? 39.632 59.847 2.123 1.00 5.83 ? 168 PRO A N 1 ATOM 1174 C CA . PRO A 1 168 ? 39.380 60.664 0.930 1.00 6.19 ? 168 PRO A CA 1 ATOM 1175 C C . PRO A 1 168 ? 37.915 60.668 0.500 1.00 5.54 ? 168 PRO A C 1 ATOM 1176 O O . PRO A 1 168 ? 37.171 59.730 0.769 1.00 6.23 ? 168 PRO A O 1 ATOM 1177 C CB . PRO A 1 168 ? 40.234 59.983 -0.137 1.00 7.30 ? 168 PRO A CB 1 ATOM 1178 C CG . PRO A 1 168 ? 40.286 58.585 0.303 1.00 6.17 ? 168 PRO A CG 1 ATOM 1179 C CD . PRO A 1 168 ? 40.394 58.638 1.789 1.00 6.68 ? 168 PRO A CD 1 ATOM 1180 N N . ASP A 1 169 ? 37.543 61.739 -0.176 1.00 5.63 ? 169 ASP A N 1 ATOM 1181 C CA . ASP A 1 169 ? 36.340 61.736 -1.002 1.00 5.64 ? 169 ASP A CA 1 ATOM 1182 C C . ASP A 1 169 ? 36.467 60.562 -1.975 1.00 5.62 ? 169 ASP A C 1 ATOM 1183 O O . ASP A 1 169 ? 37.569 60.204 -2.427 1.00 6.77 ? 169 ASP A O 1 ATOM 1184 C CB . ASP A 1 169 ? 36.338 63.027 -1.825 1.00 5.74 ? 169 ASP A CB 1 ATOM 1185 C CG . ASP A 1 169 ? 35.155 63.092 -2.772 1.00 6.09 ? 169 ASP A CG 1 ATOM 1186 O OD1 . ASP A 1 169 ? 34.057 62.617 -2.463 1.00 7.48 ? 169 ASP A OD1 1 ATOM 1187 O OD2 . ASP A 1 169 ? 35.301 63.686 -3.869 1.00 8.20 ? 169 ASP A OD2 1 ATOM 1188 N N . GLU A 1 170 ? 35.334 59.965 -2.320 1.00 5.92 ? 170 GLU A N 1 ATOM 1189 C CA . GLU A 1 170 ? 35.322 58.846 -3.258 1.00 5.74 ? 170 GLU A CA 1 ATOM 1190 C C . GLU A 1 170 ? 34.588 59.215 -4.570 1.00 5.89 ? 170 GLU A C 1 ATOM 1191 O O . GLU A 1 170 ? 34.593 58.414 -5.525 1.00 5.96 ? 170 GLU A O 1 ATOM 1192 C CB . GLU A 1 170 ? 34.643 57.600 -2.630 1.00 8.00 ? 170 GLU A CB 1 ATOM 1193 C CG . GLU A 1 170 ? 35.414 57.202 -1.316 1.00 7.86 ? 170 GLU A CG 1 ATOM 1194 C CD . GLU A 1 170 ? 34.926 55.924 -0.675 1.00 8.29 ? 170 GLU A CD 1 ATOM 1195 O OE1 . GLU A 1 170 ? 34.181 55.165 -1.304 1.00 8.56 ? 170 GLU A OE1 1 ATOM 1196 O OE2 . GLU A 1 170 ? 35.311 55.696 0.533 1.00 10.05 ? 170 GLU A OE2 1 ATOM 1197 N N . ALA A 1 171 ? 34.020 60.400 -4.663 1.00 5.64 ? 171 ALA A N 1 ATOM 1198 C CA . ALA A 1 171 ? 33.271 60.767 -5.887 1.00 5.32 ? 171 ALA A CA 1 ATOM 1199 C C . ALA A 1 171 ? 34.129 61.538 -6.890 1.00 6.21 ? 171 ALA A C 1 ATOM 1200 O O . ALA A 1 171 ? 34.154 61.252 -8.110 1.00 6.80 ? 171 ALA A O 1 ATOM 1201 C CB . ALA A 1 171 ? 32.104 61.661 -5.509 1.00 6.38 ? 171 ALA A CB 1 ATOM 1202 N N . ASN A 1 172 ? 34.849 62.557 -6.408 1.00 5.79 ? 172 ASN A N 1 ATOM 1203 C CA . ASN A 1 172 ? 35.615 63.447 -7.333 1.00 5.59 ? 172 ASN A CA 1 ATOM 1204 C C . ASN A 1 172 ? 37.061 63.060 -7.471 1.00 5.60 ? 172 ASN A C 1 ATOM 1205 O O . ASN A 1 172 ? 37.740 63.501 -8.422 1.00 6.55 ? 172 ASN A O 1 ATOM 1206 C CB . ASN A 1 172 ? 35.556 64.869 -6.742 1.00 6.19 ? 172 ASN A CB 1 ATOM 1207 C CG . ASN A 1 172 ? 34.152 65.414 -6.635 1.00 7.95 ? 172 ASN A CG 1 ATOM 1208 O OD1 . ASN A 1 172 ? 33.471 65.645 -7.635 1.00 9.73 ? 172 ASN A OD1 1 ATOM 1209 N ND2 . ASN A 1 172 ? 33.721 65.711 -5.403 1.00 8.42 ? 172 ASN A ND2 1 ATOM 1210 N N . SER A 1 173 ? 37.583 62.277 -6.545 1.00 5.28 ? 173 SER A N 1 ATOM 1211 C CA . SER A 1 173 ? 38.984 61.936 -6.539 1.00 4.76 ? 173 SER A CA 1 ATOM 1212 C C . SER A 1 173 ? 39.368 61.046 -7.689 1.00 4.53 ? 173 SER A C 1 ATOM 1213 O O . SER A 1 173 ? 38.620 60.117 -8.070 1.00 5.90 ? 173 SER A O 1 ATOM 1214 C CB . SER A 1 173 ? 39.324 61.255 -5.207 1.00 6.43 ? 173 SER A CB 1 ATOM 1215 O OG . SER A 1 173 ? 38.403 60.132 -5.020 1.00 6.56 ? 173 SER A OG 1 ATOM 1216 N N . HIS A 1 174 ? 40.555 61.279 -8.247 1.00 4.55 ? 174 HIS A N 1 ATOM 1217 C CA . HIS A 1 174 ? 41.078 60.380 -9.267 1.00 4.55 ? 174 HIS A CA 1 ATOM 1218 C C . HIS A 1 174 ? 41.743 59.175 -8.562 1.00 4.09 ? 174 HIS A C 1 ATOM 1219 O O . HIS A 1 174 ? 42.395 59.352 -7.515 1.00 5.33 ? 174 HIS A O 1 ATOM 1220 C CB . HIS A 1 174 ? 42.129 61.094 -10.092 1.00 5.93 ? 174 HIS A CB 1 ATOM 1221 C CG . HIS A 1 174 ? 42.398 60.421 -11.393 1.00 5.96 ? 174 HIS A CG 1 ATOM 1222 N ND1 . HIS A 1 174 ? 43.139 59.255 -11.502 1.00 7.16 ? 174 HIS A ND1 1 ATOM 1223 C CD2 . HIS A 1 174 ? 41.930 60.718 -12.637 1.00 7.47 ? 174 HIS A CD2 1 ATOM 1224 C CE1 . HIS A 1 174 ? 43.092 58.853 -12.766 1.00 7.63 ? 174 HIS A CE1 1 ATOM 1225 N NE2 . HIS A 1 174 ? 42.363 59.716 -13.453 1.00 8.16 ? 174 HIS A NE2 1 ATOM 1226 N N . TRP A 1 175 ? 41.592 57.971 -9.103 1.00 4.53 ? 175 TRP A N 1 ATOM 1227 C CA . TRP A 1 175 ? 42.182 56.786 -8.473 1.00 4.44 ? 175 TRP A CA 1 ATOM 1228 C C . TRP A 1 175 ? 43.672 56.981 -8.232 1.00 4.99 ? 175 TRP A C 1 ATOM 1229 O O . TRP A 1 175 ? 44.196 56.446 -7.252 1.00 6.02 ? 175 TRP A O 1 ATOM 1230 C CB . TRP A 1 175 ? 41.904 55.510 -9.289 1.00 4.84 ? 175 TRP A CB 1 ATOM 1231 C CG . TRP A 1 175 ? 42.734 55.320 -10.534 1.00 5.78 ? 175 TRP A CG 1 ATOM 1232 C CD1 . TRP A 1 175 ? 42.389 55.701 -11.825 1.00 5.23 ? 175 TRP A CD1 1 ATOM 1233 C CD2 . TRP A 1 175 ? 43.998 54.685 -10.621 1.00 4.86 ? 175 TRP A CD2 1 ATOM 1234 N NE1 . TRP A 1 175 ? 43.408 55.309 -12.680 1.00 6.23 ? 175 TRP A NE1 1 ATOM 1235 C CE2 . TRP A 1 175 ? 44.395 54.683 -11.979 1.00 5.55 ? 175 TRP A CE2 1 ATOM 1236 C CE3 . TRP A 1 175 ? 44.849 54.091 -9.662 1.00 6.99 ? 175 TRP A CE3 1 ATOM 1237 C CZ2 . TRP A 1 175 ? 45.625 54.133 -12.422 1.00 6.53 ? 175 TRP A CZ2 1 ATOM 1238 C CZ3 . TRP A 1 175 ? 46.044 53.531 -10.089 1.00 7.06 ? 175 TRP A CZ3 1 ATOM 1239 C CH2 . TRP A 1 175 ? 46.431 53.565 -11.479 1.00 7.94 ? 175 TRP A CH2 1 ATOM 1240 N N . ARG A 1 176 ? 44.357 57.684 -9.119 1.00 5.11 ? 176 ARG A N 1 ATOM 1241 C CA . ARG A 1 176 ? 45.808 57.875 -8.962 1.00 5.40 ? 176 ARG A CA 1 ATOM 1242 C C . ARG A 1 176 ? 46.094 58.635 -7.658 1.00 5.03 ? 176 ARG A C 1 ATOM 1243 O O . ARG A 1 176 ? 47.054 58.312 -6.958 1.00 6.09 ? 176 ARG A O 1 ATOM 1244 C CB . ARG A 1 176 ? 46.400 58.610 -10.185 1.00 6.67 ? 176 ARG A CB 1 ATOM 1245 C CG . ARG A 1 176 ? 46.490 57.718 -11.439 1.00 7.63 ? 176 ARG A CG 1 ATOM 1246 C CD . ARG A 1 176 ? 46.438 58.484 -12.766 1.00 11.03 ? 176 ARG A CD 1 ATOM 1247 N NE . ARG A 1 176 ? 47.479 59.497 -12.835 1.00 10.56 ? 176 ARG A NE 1 ATOM 1248 C CZ . ARG A 1 176 ? 47.641 60.338 -13.847 1.00 10.06 ? 176 ARG A CZ 1 ATOM 1249 N NH1 . ARG A 1 176 ? 46.817 60.322 -14.884 1.00 10.62 ? 176 ARG A NH1 1 ATOM 1250 N NH2 . ARG A 1 176 ? 48.597 61.229 -13.782 1.00 10.95 ? 176 ARG A NH2 1 ATOM 1251 N N . ASN A 1 177 ? 45.228 59.595 -7.311 1.00 4.83 ? 177 ASN A N 1 ATOM 1252 C CA . ASN A 1 177 ? 45.446 60.353 -6.083 1.00 4.48 ? 177 ASN A CA 1 ATOM 1253 C C . ASN A 1 177 ? 44.927 59.616 -4.854 1.00 4.88 ? 177 ASN A C 1 ATOM 1254 O O . ASN A 1 177 ? 45.470 59.814 -3.729 1.00 5.91 ? 177 ASN A O 1 ATOM 1255 C CB . ASN A 1 177 ? 44.859 61.752 -6.187 1.00 5.40 ? 177 ASN A CB 1 ATOM 1256 C CG . ASN A 1 177 ? 45.537 62.564 -7.211 1.00 6.66 ? 177 ASN A CG 1 ATOM 1257 O OD1 . ASN A 1 177 ? 46.694 62.364 -7.553 1.00 7.57 ? 177 ASN A OD1 1 ATOM 1258 N ND2 . ASN A 1 177 ? 44.777 63.521 -7.732 1.00 8.93 ? 177 ASN A ND2 1 ATOM 1259 N N . VAL A 1 178 ? 43.940 58.770 -5.015 1.00 5.08 ? 178 VAL A N 1 ATOM 1260 C CA . VAL A 1 178 ? 43.518 57.942 -3.879 1.00 5.85 ? 178 VAL A CA 1 ATOM 1261 C C . VAL A 1 178 ? 44.695 56.996 -3.557 1.00 5.01 ? 178 VAL A C 1 ATOM 1262 O O . VAL A 1 178 ? 45.046 56.830 -2.342 1.00 6.04 ? 178 VAL A O 1 ATOM 1263 C CB . VAL A 1 178 ? 42.313 57.062 -4.257 1.00 5.83 ? 178 VAL A CB 1 ATOM 1264 C CG1 . VAL A 1 178 ? 41.989 56.040 -3.129 1.00 7.41 ? 178 VAL A CG1 1 ATOM 1265 C CG2 . VAL A 1 178 ? 41.082 57.974 -4.484 1.00 8.07 ? 178 VAL A CG2 1 ATOM 1266 N N . LEU A 1 179 ? 45.363 56.446 -4.561 1.00 5.38 ? 179 LEU A N 1 ATOM 1267 C CA . LEU A 1 179 ? 46.510 55.604 -4.304 1.00 5.36 ? 179 LEU A CA 1 ATOM 1268 C C . LEU A 1 179 ? 47.681 56.424 -3.734 1.00 5.85 ? 179 LEU A C 1 ATOM 1269 O O . LEU A 1 179 ? 48.354 55.961 -2.771 1.00 6.05 ? 179 LEU A O 1 ATOM 1270 C CB . LEU A 1 179 ? 46.956 54.896 -5.624 1.00 5.34 ? 179 LEU A CB 1 ATOM 1271 C CG . LEU A 1 179 ? 48.304 54.106 -5.448 1.00 6.63 ? 179 LEU A CG 1 ATOM 1272 C CD1 . LEU A 1 179 ? 48.180 52.947 -4.375 1.00 6.97 ? 179 LEU A CD1 1 ATOM 1273 C CD2 . LEU A 1 179 ? 48.709 53.482 -6.805 1.00 8.32 ? 179 LEU A CD2 1 ATOM 1274 N N . LEU A 1 180 ? 47.893 57.657 -4.226 1.00 4.76 ? 180 LEU A N 1 ATOM 1275 C CA . LEU A 1 180 ? 48.988 58.479 -3.737 1.00 5.75 ? 180 LEU A CA 1 ATOM 1276 C C . LEU A 1 180 ? 48.800 58.718 -2.237 1.00 4.87 ? 180 LEU A C 1 ATOM 1277 O O . LEU A 1 180 ? 49.783 58.531 -1.446 1.00 5.63 ? 180 LEU A O 1 ATOM 1278 C CB . LEU A 1 180 ? 48.952 59.827 -4.508 1.00 6.47 ? 180 LEU A CB 1 ATOM 1279 C CG . LEU A 1 180 ? 50.069 60.793 -4.107 1.00 7.33 ? 180 LEU A CG 1 ATOM 1280 C CD1 . LEU A 1 180 ? 51.366 60.268 -4.767 1.00 9.12 ? 180 LEU A CD1 1 ATOM 1281 C CD2 . LEU A 1 180 ? 49.813 62.210 -4.648 1.00 8.80 ? 180 LEU A CD2 1 ATOM 1282 N N . GLN A 1 181 ? 47.593 59.103 -1.805 1.00 5.00 ? 181 GLN A N 1 ATOM 1283 C CA . GLN A 1 181 ? 47.444 59.443 -0.385 1.00 5.69 ? 181 GLN A CA 1 ATOM 1284 C C . GLN A 1 181 ? 47.495 58.190 0.494 1.00 5.66 ? 181 GLN A C 1 ATOM 1285 O O . GLN A 1 181 ? 48.013 58.260 1.652 1.00 5.70 ? 181 GLN A O 1 ATOM 1286 C CB . GLN A 1 181 ? 46.170 60.273 -0.175 1.00 5.73 ? 181 GLN A CB 1 ATOM 1287 C CG . GLN A 1 181 ? 44.863 59.537 -0.397 1.00 5.25 ? 181 GLN A CG 1 ATOM 1288 C CD . GLN A 1 181 ? 44.470 58.637 0.742 1.00 5.69 ? 181 GLN A CD 1 ATOM 1289 O OE1 . GLN A 1 181 ? 44.752 58.940 1.927 1.00 7.21 ? 181 GLN A OE1 1 ATOM 1290 N NE2 . GLN A 1 181 ? 43.800 57.518 0.412 1.00 7.04 ? 181 GLN A NE2 1 ATOM 1291 N N . LEU A 1 182 ? 46.997 57.052 -0.013 1.00 5.93 ? 182 LEU A N 1 ATOM 1292 C CA . LEU A 1 182 ? 47.101 55.821 0.736 1.00 5.50 ? 182 LEU A CA 1 ATOM 1293 C C . LEU A 1 182 ? 48.554 55.469 0.928 1.00 5.40 ? 182 LEU A C 1 ATOM 1294 O O . LEU A 1 182 ? 48.980 55.065 2.021 1.00 5.97 ? 182 LEU A O 1 ATOM 1295 C CB . LEU A 1 182 ? 46.382 54.675 -0.008 1.00 6.77 ? 182 LEU A CB 1 ATOM 1296 C CG . LEU A 1 182 ? 46.477 53.336 0.697 1.00 5.54 ? 182 LEU A CG 1 ATOM 1297 C CD1 . LEU A 1 182 ? 45.710 53.300 2.066 1.00 8.28 ? 182 LEU A CD1 1 ATOM 1298 C CD2 . LEU A 1 182 ? 45.891 52.227 -0.250 1.00 7.91 ? 182 LEU A CD2 1 ATOM 1299 N N . THR A 1 183 ? 49.339 55.607 -0.117 1.00 5.86 ? 183 THR A N 1 ATOM 1300 C CA . THR A 1 183 ? 50.750 55.244 -0.074 1.00 5.87 ? 183 THR A CA 1 ATOM 1301 C C . THR A 1 183 ? 51.476 56.205 0.852 1.00 5.53 ? 183 THR A C 1 ATOM 1302 O O . THR A 1 183 ? 52.419 55.779 1.598 1.00 6.30 ? 183 THR A O 1 ATOM 1303 C CB . THR A 1 183 ? 51.377 55.316 -1.513 1.00 5.58 ? 183 THR A CB 1 ATOM 1304 O OG1 . THR A 1 183 ? 50.691 54.403 -2.371 1.00 6.38 ? 183 THR A OG1 1 ATOM 1305 C CG2 . THR A 1 183 ? 52.834 54.904 -1.477 1.00 7.06 ? 183 THR A CG2 1 ATOM 1306 N N . GLU A 1 184 ? 51.135 57.495 0.853 1.00 5.68 ? 184 GLU A N 1 ATOM 1307 C CA . GLU A 1 184 ? 51.840 58.441 1.738 1.00 6.28 ? 184 GLU A CA 1 ATOM 1308 C C . GLU A 1 184 ? 51.616 58.063 3.189 1.00 5.81 ? 184 GLU A C 1 ATOM 1309 O O . GLU A 1 184 ? 52.595 58.025 3.976 1.00 7.94 ? 184 GLU A O 1 ATOM 1310 C CB . GLU A 1 184 ? 51.311 59.854 1.496 1.00 7.88 ? 184 GLU A CB 1 ATOM 1311 C CG . GLU A 1 184 ? 52.218 60.964 2.013 1.00 10.82 ? 184 GLU A CG 1 ATOM 1312 C CD . GLU A 1 184 ? 53.581 61.018 1.291 1.00 9.86 ? 184 GLU A CD 1 ATOM 1313 O OE1 . GLU A 1 184 ? 53.734 60.631 0.118 1.00 12.40 ? 184 GLU A OE1 1 ATOM 1314 O OE2 . GLU A 1 184 ? 54.500 61.496 1.964 1.00 13.42 ? 184 GLU A OE2 1 ATOM 1315 N N . GLY A 1 185 ? 50.396 57.763 3.587 1.00 6.70 ? 185 GLY A N 1 ATOM 1316 C CA . GLY A 1 185 ? 50.171 57.402 4.973 1.00 6.56 ? 185 GLY A CA 1 ATOM 1317 C C . GLY A 1 185 ? 50.740 56.042 5.321 1.00 5.91 ? 185 GLY A C 1 ATOM 1318 O O . GLY A 1 185 ? 51.338 55.859 6.406 1.00 6.89 ? 185 GLY A O 1 ATOM 1319 N N . GLN A 1 186 ? 50.604 55.053 4.438 1.00 5.71 ? 186 GLN A N 1 ATOM 1320 C CA . GLN A 1 186 ? 51.077 53.698 4.805 1.00 6.16 ? 186 GLN A CA 1 ATOM 1321 C C . GLN A 1 186 ? 52.589 53.646 4.808 1.00 6.04 ? 186 GLN A C 1 ATOM 1322 O O . GLN A 1 186 ? 53.181 52.879 5.586 1.00 7.22 ? 186 GLN A O 1 ATOM 1323 C CB . GLN A 1 186 ? 50.509 52.632 3.870 1.00 6.22 ? 186 GLN A CB 1 ATOM 1324 C CG . GLN A 1 186 ? 48.969 52.462 4.154 1.00 8.06 ? 186 GLN A CG 1 ATOM 1325 C CD . GLN A 1 186 ? 48.522 51.072 3.932 1.00 7.43 ? 186 GLN A CD 1 ATOM 1326 O OE1 . GLN A 1 186 ? 49.151 50.386 3.102 1.00 11.62 ? 186 GLN A OE1 1 ATOM 1327 N NE2 . GLN A 1 186 ? 47.471 50.618 4.577 1.00 9.30 ? 186 GLN A NE2 1 ATOM 1328 N N . THR A 1 187 ? 53.266 54.396 3.923 1.00 7.05 ? 187 THR A N 1 ATOM 1329 C CA . THR A 1 187 ? 54.725 54.404 3.930 1.00 6.22 ? 187 THR A CA 1 ATOM 1330 C C . THR A 1 187 ? 55.187 55.006 5.252 1.00 7.84 ? 187 THR A C 1 ATOM 1331 O O . THR A 1 187 ? 56.177 54.498 5.850 1.00 8.33 ? 187 THR A O 1 ATOM 1332 C CB . THR A 1 187 ? 55.260 55.180 2.741 1.00 6.60 ? 187 THR A CB 1 ATOM 1333 O OG1 . THR A 1 187 ? 54.789 54.529 1.538 1.00 7.25 ? 187 THR A OG1 1 ATOM 1334 C CG2 . THR A 1 187 ? 56.804 55.165 2.693 1.00 7.56 ? 187 THR A CG2 1 ATOM 1335 N N . TRP A 1 188 ? 54.567 56.083 5.706 1.00 6.55 ? 188 TRP A N 1 ATOM 1336 C CA . TRP A 1 188 ? 54.893 56.637 7.015 1.00 6.72 ? 188 TRP A CA 1 ATOM 1337 C C . TRP A 1 188 ? 54.680 55.619 8.141 1.00 6.77 ? 188 TRP A C 1 ATOM 1338 O O . TRP A 1 188 ? 55.547 55.422 8.986 1.00 7.29 ? 188 TRP A O 1 ATOM 1339 C CB . TRP A 1 188 ? 54.095 57.925 7.276 1.00 7.56 ? 188 TRP A CB 1 ATOM 1340 C CG . TRP A 1 188 ? 54.582 58.658 8.483 1.00 7.53 ? 188 TRP A CG 1 ATOM 1341 C CD1 . TRP A 1 188 ? 55.452 59.697 8.503 1.00 9.03 ? 188 TRP A CD1 1 ATOM 1342 C CD2 . TRP A 1 188 ? 54.252 58.377 9.850 1.00 7.83 ? 188 TRP A CD2 1 ATOM 1343 N NE1 . TRP A 1 188 ? 55.700 60.081 9.791 1.00 9.05 ? 188 TRP A NE1 1 ATOM 1344 C CE2 . TRP A 1 188 ? 54.971 59.295 10.641 1.00 8.69 ? 188 TRP A CE2 1 ATOM 1345 C CE3 . TRP A 1 188 ? 53.426 57.437 10.482 1.00 8.81 ? 188 TRP A CE3 1 ATOM 1346 C CZ2 . TRP A 1 188 ? 54.898 59.302 12.023 1.00 10.24 ? 188 TRP A CZ2 1 ATOM 1347 C CZ3 . TRP A 1 188 ? 53.358 57.444 11.869 1.00 9.09 ? 188 TRP A CZ3 1 ATOM 1348 C CH2 . TRP A 1 188 ? 54.093 58.374 12.618 1.00 9.94 ? 188 TRP A CH2 1 ATOM 1349 N N . LEU A 1 189 ? 53.542 54.938 8.130 1.00 7.12 ? 189 LEU A N 1 ATOM 1350 C CA . LEU A 1 189 ? 53.276 53.936 9.141 1.00 7.12 ? 189 LEU A CA 1 ATOM 1351 C C . LEU A 1 189 ? 54.286 52.800 9.147 1.00 7.11 ? 189 LEU A C 1 ATOM 1352 O O . LEU A 1 189 ? 54.670 52.351 10.218 1.00 9.16 ? 189 LEU A O 1 ATOM 1353 C CB . LEU A 1 189 ? 51.866 53.354 9.004 1.00 7.69 ? 189 LEU A CB 1 ATOM 1354 C CG . LEU A 1 189 ? 50.721 54.256 9.493 1.00 6.89 ? 189 LEU A CG 1 ATOM 1355 C CD1 . LEU A 1 189 ? 49.418 53.535 9.187 1.00 7.83 ? 189 LEU A CD1 1 ATOM 1356 C CD2 . LEU A 1 189 ? 50.823 54.517 10.996 1.00 7.86 ? 189 LEU A CD2 1 ATOM 1357 N N . LYS A 1 190 ? 54.709 52.331 7.976 1.00 6.70 ? 190 LYS A N 1 ATOM 1358 C CA . LYS A 1 190 ? 55.649 51.221 7.949 1.00 8.70 ? 190 LYS A CA 1 ATOM 1359 C C . LYS A 1 190 ? 56.992 51.714 8.527 1.00 9.80 ? 190 LYS A C 1 ATOM 1360 O O . LYS A 1 190 ? 57.608 51.008 9.359 1.00 10.11 ? 190 LYS A O 1 ATOM 1361 C CB . LYS A 1 190 ? 55.893 50.715 6.510 1.00 9.94 ? 190 LYS A CB 1 ATOM 1362 C CG . LYS A 1 190 ? 56.875 49.495 6.486 1.00 11.33 ? 190 LYS A CG 1 ATOM 1363 C CD . LYS A 1 190 ? 57.039 48.954 5.118 1.00 17.50 ? 190 LYS A CD 1 ATOM 1364 C CE . LYS A 1 190 ? 57.877 47.679 5.135 1.00 23.50 ? 190 LYS A CE 1 ATOM 1365 N NZ . LYS A 1 190 ? 58.188 47.262 3.702 1.00 21.63 ? 190 LYS A NZ 1 ATOM 1366 N N . GLN A 1 191 ? 57.460 52.883 8.123 1.00 9.39 ? 191 GLN A N 1 ATOM 1367 C CA . GLN A 1 191 ? 58.741 53.412 8.604 1.00 11.11 ? 191 GLN A CA 1 ATOM 1368 C C . GLN A 1 191 ? 58.755 53.656 10.108 1.00 11.41 ? 191 GLN A C 1 ATOM 1369 O O . GLN A 1 191 ? 59.691 53.251 10.779 1.00 16.00 ? 191 GLN A O 1 ATOM 1370 C CB . GLN A 1 191 ? 59.078 54.699 7.851 1.00 12.35 ? 191 GLN A CB 1 ATOM 1371 C CG . GLN A 1 191 ? 60.458 55.311 8.217 1.00 20.38 ? 191 GLN A CG 1 ATOM 1372 C CD . GLN A 1 191 ? 60.846 56.493 7.320 1.00 21.74 ? 191 GLN A CD 1 ATOM 1373 O OE1 . GLN A 1 191 ? 60.097 56.885 6.443 1.00 37.16 ? 191 GLN A OE1 1 ATOM 1374 N NE2 . GLN A 1 191 ? 62.019 57.067 7.563 1.00 25.71 ? 191 GLN A NE2 1 ATOM 1375 N N . PHE A 1 192 ? 57.750 54.344 10.643 1.00 10.46 ? 192 PHE A N 1 ATOM 1376 C CA . PHE A 1 192 ? 57.790 54.752 12.032 1.00 10.40 ? 192 PHE A CA 1 ATOM 1377 C C . PHE A 1 192 ? 57.046 53.876 13.021 1.00 13.42 ? 192 PHE A C 1 ATOM 1378 O O . PHE A 1 192 ? 57.449 53.799 14.202 1.00 16.18 ? 192 PHE A O 1 ATOM 1379 C CB . PHE A 1 192 ? 57.302 56.203 12.137 1.00 9.07 ? 192 PHE A CB 1 ATOM 1380 C CG . PHE A 1 192 ? 58.192 57.184 11.404 1.00 10.91 ? 192 PHE A CG 1 ATOM 1381 C CD1 . PHE A 1 192 ? 59.431 57.529 11.999 1.00 13.40 ? 192 PHE A CD1 1 ATOM 1382 C CD2 . PHE A 1 192 ? 57.890 57.679 10.132 1.00 11.89 ? 192 PHE A CD2 1 ATOM 1383 C CE1 . PHE A 1 192 ? 60.340 58.354 11.295 1.00 14.20 ? 192 PHE A CE1 1 ATOM 1384 C CE2 . PHE A 1 192 ? 58.774 58.490 9.438 1.00 12.86 ? 192 PHE A CE2 1 ATOM 1385 C CZ . PHE A 1 192 ? 60.035 58.824 10.057 1.00 14.26 ? 192 PHE A CZ 1 ATOM 1386 N N . MET A 1 193 ? 56.006 53.183 12.577 1.00 10.23 ? 193 MET A N 1 ATOM 1387 C CA . MET A 1 193 ? 55.209 52.374 13.486 1.00 9.73 ? 193 MET A CA 1 ATOM 1388 C C . MET A 1 193 ? 55.363 50.877 13.244 1.00 8.47 ? 193 MET A C 1 ATOM 1389 O O . MET A 1 193 ? 54.893 50.080 14.037 1.00 11.83 ? 193 MET A O 1 ATOM 1390 C CB A MET A 1 193 ? 53.701 52.657 13.406 0.50 10.73 ? 193 MET A CB 1 ATOM 1391 C CB B MET A 1 193 ? 53.789 52.953 13.502 0.50 10.80 ? 193 MET A CB 1 ATOM 1392 C CG A MET A 1 193 ? 53.198 53.927 14.083 0.50 12.08 ? 193 MET A CG 1 ATOM 1393 C CG B MET A 1 193 ? 53.751 54.483 13.575 0.50 12.12 ? 193 MET A CG 1 ATOM 1394 S SD A MET A 1 193 ? 53.533 54.116 15.857 0.50 22.77 ? 193 MET A SD 1 ATOM 1395 S SD B MET A 1 193 ? 54.539 55.187 15.037 0.50 34.08 ? 193 MET A SD 1 ATOM 1396 C CE A MET A 1 193 ? 54.736 55.374 15.519 0.50 26.76 ? 193 MET A CE 1 ATOM 1397 C CE B MET A 1 193 ? 53.555 54.193 16.136 0.50 34.89 ? 193 MET A CE 1 ATOM 1398 N N . ASN A 1 194 ? 56.003 50.509 12.140 1.00 9.18 ? 194 ASN A N 1 ATOM 1399 C CA . ASN A 1 194 ? 56.157 49.114 11.742 1.00 10.09 ? 194 ASN A CA 1 ATOM 1400 C C . ASN A 1 194 ? 54.831 48.333 11.613 1.00 12.13 ? 194 ASN A C 1 ATOM 1401 O O . ASN A 1 194 ? 54.705 47.174 12.088 1.00 13.03 ? 194 ASN A O 1 ATOM 1402 C CB . ASN A 1 194 ? 57.088 48.384 12.753 1.00 13.28 ? 194 ASN A CB 1 ATOM 1403 C CG . ASN A 1 194 ? 57.557 47.042 12.222 1.00 15.37 ? 194 ASN A CG 1 ATOM 1404 O OD1 . ASN A 1 194 ? 57.681 46.848 11.012 1.00 18.38 ? 194 ASN A OD1 1 ATOM 1405 N ND2 . ASN A 1 194 ? 57.817 46.127 13.155 1.00 19.29 ? 194 ASN A ND2 1 ATOM 1406 N N . VAL A 1 195 ? 53.806 48.983 11.062 1.00 9.77 ? 195 VAL A N 1 ATOM 1407 C CA . VAL A 1 195 ? 52.514 48.338 10.826 1.00 9.53 ? 195 VAL A CA 1 ATOM 1408 C C . VAL A 1 195 ? 51.962 48.751 9.488 1.00 9.03 ? 195 VAL A C 1 ATOM 1409 O O . VAL A 1 195 ? 52.254 49.825 9.022 1.00 9.64 ? 195 VAL A O 1 ATOM 1410 C CB . VAL A 1 195 ? 51.477 48.665 11.935 1.00 12.04 ? 195 VAL A CB 1 ATOM 1411 C CG1 . VAL A 1 195 ? 51.933 48.150 13.291 1.00 18.25 ? 195 VAL A CG1 1 ATOM 1412 C CG2 . VAL A 1 195 ? 51.151 50.137 11.987 1.00 13.48 ? 195 VAL A CG2 1 ATOM 1413 N N . THR A 1 196 ? 51.155 47.877 8.898 1.00 9.38 ? 196 THR A N 1 ATOM 1414 C CA . THR A 1 196 ? 50.449 48.153 7.622 1.00 9.12 ? 196 THR A CA 1 ATOM 1415 C C . THR A 1 196 ? 48.994 47.692 7.837 1.00 9.27 ? 196 THR A C 1 ATOM 1416 O O . THR A 1 196 ? 48.722 46.485 7.905 1.00 10.66 ? 196 THR A O 1 ATOM 1417 C CB . THR A 1 196 ? 51.069 47.392 6.408 1.00 9.61 ? 196 THR A CB 1 ATOM 1418 O OG1 . THR A 1 196 ? 52.465 47.772 6.292 1.00 12.27 ? 196 THR A OG1 1 ATOM 1419 C CG2 . THR A 1 196 ? 50.334 47.753 5.129 1.00 12.06 ? 196 THR A CG2 1 ATOM 1420 N N . PRO A 1 197 ? 48.046 48.609 7.942 1.00 8.41 ? 197 PRO A N 1 ATOM 1421 C CA . PRO A 1 197 ? 46.664 48.228 8.151 1.00 8.32 ? 197 PRO A CA 1 ATOM 1422 C C . PRO A 1 197 ? 46.132 47.373 7.046 1.00 7.33 ? 197 PRO A C 1 ATOM 1423 O O . PRO A 1 197 ? 46.455 47.579 5.852 1.00 8.37 ? 197 PRO A O 1 ATOM 1424 C CB . PRO A 1 197 ? 45.938 49.582 8.101 1.00 8.59 ? 197 PRO A CB 1 ATOM 1425 C CG . PRO A 1 197 ? 46.935 50.528 8.682 1.00 8.62 ? 197 PRO A CG 1 ATOM 1426 C CD . PRO A 1 197 ? 48.247 50.076 8.077 1.00 9.12 ? 197 PRO A CD 1 ATOM 1427 N N . THR A 1 198 ? 45.272 46.411 7.402 1.00 7.43 ? 198 THR A N 1 ATOM 1428 C CA . THR A 1 198 ? 44.610 45.580 6.404 1.00 7.36 ? 198 THR A CA 1 ATOM 1429 C C . THR A 1 198 ? 43.090 45.745 6.470 1.00 6.84 ? 198 THR A C 1 ATOM 1430 O O . THR A 1 198 ? 42.341 45.047 5.754 1.00 7.55 ? 198 THR A O 1 ATOM 1431 C CB . THR A 1 198 ? 44.944 44.104 6.534 1.00 8.94 ? 198 THR A CB 1 ATOM 1432 O OG1 . THR A 1 198 ? 44.509 43.671 7.821 1.00 11.54 ? 198 THR A OG1 1 ATOM 1433 C CG2 . THR A 1 198 ? 46.446 43.899 6.383 1.00 11.11 ? 198 THR A CG2 1 ATOM 1434 N N . ALA A 1 199 ? 42.613 46.609 7.358 1.00 6.58 ? 199 ALA A N 1 ATOM 1435 C CA . ALA A 1 199 ? 41.191 46.950 7.475 1.00 6.62 ? 199 ALA A CA 1 ATOM 1436 C C . ALA A 1 199 ? 41.021 48.447 7.238 1.00 7.34 ? 199 ALA A C 1 ATOM 1437 O O . ALA A 1 199 ? 41.752 49.244 7.794 1.00 8.00 ? 199 ALA A O 1 ATOM 1438 C CB . ALA A 1 199 ? 40.663 46.596 8.889 1.00 7.57 ? 199 ALA A CB 1 ATOM 1439 N N . SER A 1 200 ? 40.047 48.802 6.410 1.00 6.43 ? 200 SER A N 1 ATOM 1440 C CA . SER A 1 200 ? 39.760 50.200 6.089 1.00 6.56 ? 200 SER A CA 1 ATOM 1441 C C . SER A 1 200 ? 38.502 50.676 6.783 1.00 7.31 ? 200 SER A C 1 ATOM 1442 O O . SER A 1 200 ? 37.537 49.928 6.965 1.00 8.27 ? 200 SER A O 1 ATOM 1443 C CB . SER A 1 200 ? 39.612 50.329 4.574 1.00 7.44 ? 200 SER A CB 1 ATOM 1444 O OG . SER A 1 200 ? 39.426 51.698 4.181 1.00 10.65 ? 200 SER A OG 1 ATOM 1445 N N . TRP A 1 201 ? 38.477 51.965 7.113 1.00 6.57 ? 201 TRP A N 1 ATOM 1446 C CA . TRP A 1 201 ? 37.396 52.650 7.851 1.00 6.46 ? 201 TRP A CA 1 ATOM 1447 C C . TRP A 1 201 ? 37.055 53.941 7.113 1.00 6.71 ? 201 TRP A C 1 ATOM 1448 O O . TRP A 1 201 ? 37.848 54.864 7.086 1.00 8.73 ? 201 TRP A O 1 ATOM 1449 C CB . TRP A 1 201 ? 37.921 52.971 9.249 1.00 7.23 ? 201 TRP A CB 1 ATOM 1450 C CG . TRP A 1 201 ? 37.118 53.781 10.236 1.00 7.58 ? 201 TRP A CG 1 ATOM 1451 C CD1 . TRP A 1 201 ? 37.284 55.105 10.527 1.00 7.92 ? 201 TRP A CD1 1 ATOM 1452 C CD2 . TRP A 1 201 ? 36.164 53.286 11.172 1.00 7.27 ? 201 TRP A CD2 1 ATOM 1453 N NE1 . TRP A 1 201 ? 36.467 55.466 11.556 1.00 8.33 ? 201 TRP A NE1 1 ATOM 1454 C CE2 . TRP A 1 201 ? 35.757 54.375 11.968 1.00 7.07 ? 201 TRP A CE2 1 ATOM 1455 C CE3 . TRP A 1 201 ? 35.594 52.032 11.401 1.00 8.19 ? 201 TRP A CE3 1 ATOM 1456 C CZ2 . TRP A 1 201 ? 34.809 54.248 12.976 1.00 8.51 ? 201 TRP A CZ2 1 ATOM 1457 C CZ3 . TRP A 1 201 ? 34.657 51.908 12.403 1.00 9.46 ? 201 TRP A CZ3 1 ATOM 1458 C CH2 . TRP A 1 201 ? 34.275 53.007 13.179 1.00 9.53 ? 201 TRP A CH2 1 ATOM 1459 N N . ALA A 1 202 ? 35.886 53.986 6.498 1.00 6.90 ? 202 ALA A N 1 ATOM 1460 C CA . ALA A 1 202 ? 35.450 55.191 5.733 1.00 6.32 ? 202 ALA A CA 1 ATOM 1461 C C . ALA A 1 202 ? 34.018 55.544 6.168 1.00 7.45 ? 202 ALA A C 1 ATOM 1462 O O . ALA A 1 202 ? 33.036 55.118 5.581 1.00 8.70 ? 202 ALA A O 1 ATOM 1463 C CB . ALA A 1 202 ? 35.521 54.860 4.237 1.00 9.12 ? 202 ALA A CB 1 ATOM 1464 N N . ILE A 1 203 ? 33.939 56.328 7.245 1.00 6.81 ? 203 ILE A N 1 ATOM 1465 C CA . ILE A 1 203 ? 32.644 56.639 7.869 1.00 6.85 ? 203 ILE A CA 1 ATOM 1466 C C . ILE A 1 203 ? 32.001 57.920 7.416 1.00 6.83 ? 203 ILE A C 1 ATOM 1467 O O . ILE A 1 203 ? 30.821 58.129 7.663 1.00 7.43 ? 203 ILE A O 1 ATOM 1468 C CB . ILE A 1 203 ? 32.763 56.658 9.440 1.00 7.18 ? 203 ILE A CB 1 ATOM 1469 C CG1 . ILE A 1 203 ? 33.900 57.595 9.898 1.00 7.15 ? 203 ILE A CG1 1 ATOM 1470 C CG2 . ILE A 1 203 ? 33.052 55.209 9.934 1.00 8.36 ? 203 ILE A CG2 1 ATOM 1471 C CD1 . ILE A 1 203 ? 33.829 57.894 11.424 1.00 7.12 ? 203 ILE A CD1 1 ATOM 1472 N N . ASP A 1 204 ? 32.761 58.785 6.716 1.00 6.63 ? 204 ASP A N 1 ATOM 1473 C CA . ASP A 1 204 ? 32.198 60.091 6.328 1.00 6.84 ? 204 ASP A CA 1 ATOM 1474 C C . ASP A 1 204 ? 32.132 60.493 4.845 1.00 7.31 ? 204 ASP A C 1 ATOM 1475 O O . ASP A 1 204 ? 31.399 61.441 4.555 1.00 8.28 ? 204 ASP A O 1 ATOM 1476 C CB . ASP A 1 204 ? 32.890 61.209 7.126 1.00 7.32 ? 204 ASP A CB 1 ATOM 1477 C CG . ASP A 1 204 ? 31.987 62.425 7.415 1.00 6.03 ? 204 ASP A CG 1 ATOM 1478 O OD1 . ASP A 1 204 ? 30.750 62.291 7.475 1.00 7.34 ? 204 ASP A OD1 1 ATOM 1479 O OD2 . ASP A 1 204 ? 32.489 63.558 7.627 1.00 6.77 ? 204 ASP A OD2 1 ATOM 1480 N N . PRO A 1 205 ? 32.855 59.854 3.887 1.00 6.28 ? 205 PRO A N 1 ATOM 1481 C CA . PRO A 1 205 ? 32.712 60.298 2.467 1.00 6.65 ? 205 PRO A CA 1 ATOM 1482 C C . PRO A 1 205 ? 31.241 60.202 2.043 1.00 6.45 ? 205 PRO A C 1 ATOM 1483 O O . PRO A 1 205 ? 30.473 59.331 2.517 1.00 7.50 ? 205 PRO A O 1 ATOM 1484 C CB . PRO A 1 205 ? 33.583 59.324 1.686 1.00 8.68 ? 205 PRO A CB 1 ATOM 1485 C CG . PRO A 1 205 ? 34.685 58.923 2.665 1.00 12.06 ? 205 PRO A CG 1 ATOM 1486 C CD . PRO A 1 205 ? 33.853 58.769 3.989 1.00 9.04 ? 205 PRO A CD 1 ATOM 1487 N N . PHE A 1 206 ? 30.847 61.079 1.099 1.00 6.02 ? 206 PHE A N 1 ATOM 1488 C CA . PHE A 1 206 ? 29.392 61.251 0.847 1.00 6.96 ? 206 PHE A CA 1 ATOM 1489 C C . PHE A 1 206 ? 28.974 60.337 -0.318 1.00 6.43 ? 206 PHE A C 1 ATOM 1490 O O . PHE A 1 206 ? 28.747 60.736 -1.479 1.00 7.43 ? 206 PHE A O 1 ATOM 1491 C CB . PHE A 1 206 ? 29.119 62.722 0.525 1.00 6.85 ? 206 PHE A CB 1 ATOM 1492 C CG . PHE A 1 206 ? 29.918 63.723 1.351 1.00 6.15 ? 206 PHE A CG 1 ATOM 1493 C CD1 . PHE A 1 206 ? 30.195 63.487 2.691 1.00 6.44 ? 206 PHE A CD1 1 ATOM 1494 C CD2 . PHE A 1 206 ? 30.442 64.891 0.727 1.00 6.58 ? 206 PHE A CD2 1 ATOM 1495 C CE1 . PHE A 1 206 ? 31.005 64.403 3.404 1.00 7.55 ? 206 PHE A CE1 1 ATOM 1496 C CE2 . PHE A 1 206 ? 31.249 65.769 1.457 1.00 6.20 ? 206 PHE A CE2 1 ATOM 1497 C CZ . PHE A 1 206 ? 31.517 65.505 2.806 1.00 6.81 ? 206 PHE A CZ 1 ATOM 1498 N N . GLY A 1 207 ? 28.819 59.059 0.017 1.00 6.73 ? 207 GLY A N 1 ATOM 1499 C CA . GLY A 1 207 ? 28.619 58.026 -0.976 1.00 7.48 ? 207 GLY A CA 1 ATOM 1500 C C . GLY A 1 207 ? 29.974 57.312 -1.171 1.00 5.77 ? 207 GLY A C 1 ATOM 1501 O O . GLY A 1 207 ? 31.065 57.819 -0.848 1.00 6.86 ? 207 GLY A O 1 ATOM 1502 N N . HIS A 1 208 ? 29.923 56.099 -1.734 1.00 5.71 ? 208 HIS A N 1 ATOM 1503 C CA . HIS A 1 208 ? 31.106 55.215 -1.846 1.00 5.73 ? 208 HIS A CA 1 ATOM 1504 C C . HIS A 1 208 ? 31.310 54.586 -3.196 1.00 5.82 ? 208 HIS A C 1 ATOM 1505 O O . HIS A 1 208 ? 30.324 54.257 -3.912 1.00 7.21 ? 208 HIS A O 1 ATOM 1506 C CB . HIS A 1 208 ? 30.998 54.089 -0.764 1.00 6.61 ? 208 HIS A CB 1 ATOM 1507 C CG . HIS A 1 208 ? 31.068 54.627 0.645 1.00 7.38 ? 208 HIS A CG 1 ATOM 1508 N ND1 . HIS A 1 208 ? 32.272 54.877 1.273 1.00 8.91 ? 208 HIS A ND1 1 ATOM 1509 C CD2 . HIS A 1 208 ? 30.093 54.959 1.526 1.00 8.83 ? 208 HIS A CD2 1 ATOM 1510 C CE1 . HIS A 1 208 ? 32.003 55.344 2.506 1.00 8.54 ? 208 HIS A CE1 1 ATOM 1511 N NE2 . HIS A 1 208 ? 30.714 55.392 2.683 1.00 10.79 ? 208 HIS A NE2 1 ATOM 1512 N N . SER A 1 209 ? 32.577 54.463 -3.598 1.00 5.49 ? 209 SER A N 1 ATOM 1513 C CA . SER A 1 209 ? 32.967 53.980 -4.901 1.00 5.40 ? 209 SER A CA 1 ATOM 1514 C C . SER A 1 209 ? 33.677 52.635 -4.846 1.00 5.42 ? 209 SER A C 1 ATOM 1515 O O . SER A 1 209 ? 34.497 52.388 -3.966 1.00 5.95 ? 209 SER A O 1 ATOM 1516 C CB . SER A 1 209 ? 33.962 54.980 -5.505 1.00 6.37 ? 209 SER A CB 1 ATOM 1517 O OG . SER A 1 209 ? 34.449 54.468 -6.741 1.00 6.58 ? 209 SER A OG 1 ATOM 1518 N N . PRO A 1 210 ? 33.431 51.750 -5.824 1.00 5.32 ? 210 PRO A N 1 ATOM 1519 C CA . PRO A 1 210 ? 34.128 50.454 -5.861 1.00 6.20 ? 210 PRO A CA 1 ATOM 1520 C C . PRO A 1 210 ? 35.622 50.652 -6.193 1.00 5.60 ? 210 PRO A C 1 ATOM 1521 O O . PRO A 1 210 ? 36.416 49.700 -6.135 1.00 6.26 ? 210 PRO A O 1 ATOM 1522 C CB . PRO A 1 210 ? 33.391 49.672 -6.950 1.00 6.40 ? 210 PRO A CB 1 ATOM 1523 C CG . PRO A 1 210 ? 32.827 50.787 -7.838 1.00 7.94 ? 210 PRO A CG 1 ATOM 1524 C CD . PRO A 1 210 ? 32.422 51.890 -6.891 1.00 7.00 ? 210 PRO A CD 1 ATOM 1525 N N . THR A 1 211 ? 36.042 51.880 -6.580 1.00 6.16 ? 211 THR A N 1 ATOM 1526 C CA . THR A 1 211 ? 37.479 52.086 -6.768 1.00 5.97 ? 211 THR A CA 1 ATOM 1527 C C . THR A 1 211 ? 38.226 51.843 -5.447 1.00 5.67 ? 211 THR A C 1 ATOM 1528 O O . THR A 1 211 ? 39.385 51.461 -5.501 1.00 6.33 ? 211 THR A O 1 ATOM 1529 C CB . THR A 1 211 ? 37.708 53.529 -7.237 1.00 6.64 ? 211 THR A CB 1 ATOM 1530 O OG1 . THR A 1 211 ? 37.146 53.608 -8.574 1.00 7.36 ? 211 THR A OG1 1 ATOM 1531 C CG2 . THR A 1 211 ? 39.208 53.922 -7.254 1.00 7.87 ? 211 THR A CG2 1 ATOM 1532 N N . MET A 1 212 ? 37.580 52.080 -4.291 1.00 5.96 ? 212 MET A N 1 ATOM 1533 C CA . MET A 1 212 ? 38.252 51.827 -3.019 1.00 5.79 ? 212 MET A CA 1 ATOM 1534 C C . MET A 1 212 ? 38.605 50.338 -2.810 1.00 6.59 ? 212 MET A C 1 ATOM 1535 O O . MET A 1 212 ? 39.764 50.040 -2.615 1.00 6.76 ? 212 MET A O 1 ATOM 1536 C CB . MET A 1 212 ? 37.426 52.405 -1.862 1.00 8.19 ? 212 MET A CB 1 ATOM 1537 C CG A MET A 1 212 ? 37.164 53.911 -1.955 0.50 9.82 ? 212 MET A CG 1 ATOM 1538 C CG B MET A 1 212 ? 38.211 52.439 -0.607 0.50 26.74 ? 212 MET A CG 1 ATOM 1539 S SD A MET A 1 212 ? 38.673 54.892 -2.224 0.50 13.36 ? 212 MET A SD 1 ATOM 1540 S SD B MET A 1 212 ? 39.767 53.362 -0.764 0.50 43.52 ? 212 MET A SD 1 ATOM 1541 C CE A MET A 1 212 ? 39.391 54.811 -0.638 0.50 13.51 ? 212 MET A CE 1 ATOM 1542 C CE B MET A 1 212 ? 39.210 54.996 -0.591 0.50 15.28 ? 212 MET A CE 1 ATOM 1543 N N . PRO A 1 213 ? 37.643 49.391 -2.869 1.00 6.04 ? 213 PRO A N 1 ATOM 1544 C CA . PRO A 1 213 ? 38.068 47.999 -2.689 1.00 6.78 ? 213 PRO A CA 1 ATOM 1545 C C . PRO A 1 213 ? 39.044 47.594 -3.804 1.00 7.76 ? 213 PRO A C 1 ATOM 1546 O O . PRO A 1 213 ? 39.907 46.744 -3.560 1.00 7.67 ? 213 PRO A O 1 ATOM 1547 C CB . PRO A 1 213 ? 36.747 47.219 -2.722 1.00 7.83 ? 213 PRO A CB 1 ATOM 1548 C CG . PRO A 1 213 ? 35.717 48.173 -3.420 1.00 6.74 ? 213 PRO A CG 1 ATOM 1549 C CD . PRO A 1 213 ? 36.173 49.527 -2.848 1.00 6.77 ? 213 PRO A CD 1 ATOM 1550 N N . TYR A 1 214 ? 38.896 48.126 -5.014 1.00 6.72 ? 214 TYR A N 1 ATOM 1551 C CA . TYR A 1 214 ? 39.870 47.840 -6.070 1.00 6.26 ? 214 TYR A CA 1 ATOM 1552 C C . TYR A 1 214 ? 41.296 48.122 -5.627 1.00 7.15 ? 214 TYR A C 1 ATOM 1553 O O . TYR A 1 214 ? 42.144 47.242 -5.711 1.00 7.56 ? 214 TYR A O 1 ATOM 1554 C CB . TYR A 1 214 ? 39.574 48.638 -7.319 1.00 7.56 ? 214 TYR A CB 1 ATOM 1555 C CG . TYR A 1 214 ? 40.510 48.389 -8.500 1.00 7.76 ? 214 TYR A CG 1 ATOM 1556 C CD1 . TYR A 1 214 ? 40.310 47.319 -9.358 1.00 13.09 ? 214 TYR A CD1 1 ATOM 1557 C CD2 . TYR A 1 214 ? 41.567 49.251 -8.777 1.00 7.83 ? 214 TYR A CD2 1 ATOM 1558 C CE1 . TYR A 1 214 ? 41.127 47.113 -10.458 1.00 14.71 ? 214 TYR A CE1 1 ATOM 1559 C CE2 . TYR A 1 214 ? 42.383 49.045 -9.878 1.00 8.24 ? 214 TYR A CE2 1 ATOM 1560 C CZ . TYR A 1 214 ? 42.147 47.988 -10.713 1.00 11.94 ? 214 TYR A CZ 1 ATOM 1561 O OH . TYR A 1 214 ? 42.947 47.799 -11.803 1.00 12.76 ? 214 TYR A OH 1 ATOM 1562 N N . ILE A 1 215 ? 41.549 49.352 -5.190 1.00 6.07 ? 215 ILE A N 1 ATOM 1563 C CA . ILE A 1 215 ? 42.892 49.721 -4.754 1.00 5.43 ? 215 ILE A CA 1 ATOM 1564 C C . ILE A 1 215 ? 43.290 48.988 -3.461 1.00 6.21 ? 215 ILE A C 1 ATOM 1565 O O . ILE A 1 215 ? 44.411 48.507 -3.338 1.00 6.54 ? 215 ILE A O 1 ATOM 1566 C CB . ILE A 1 215 ? 42.946 51.248 -4.529 1.00 5.99 ? 215 ILE A CB 1 ATOM 1567 C CG1 . ILE A 1 215 ? 42.783 51.976 -5.851 1.00 7.07 ? 215 ILE A CG1 1 ATOM 1568 C CG2 . ILE A 1 215 ? 44.272 51.632 -3.840 1.00 8.07 ? 215 ILE A CG2 1 ATOM 1569 C CD1 . ILE A 1 215 ? 42.689 53.489 -5.720 1.00 10.52 ? 215 ILE A CD1 1 ATOM 1570 N N . LEU A 1 216 ? 42.364 48.919 -2.509 1.00 5.72 ? 216 LEU A N 1 ATOM 1571 C CA . LEU A 1 216 ? 42.700 48.303 -1.194 1.00 6.65 ? 216 LEU A CA 1 ATOM 1572 C C . LEU A 1 216 ? 43.038 46.822 -1.357 1.00 6.80 ? 216 LEU A C 1 ATOM 1573 O O . LEU A 1 216 ? 44.014 46.370 -0.749 1.00 6.64 ? 216 LEU A O 1 ATOM 1574 C CB . LEU A 1 216 ? 41.514 48.478 -0.251 1.00 5.97 ? 216 LEU A CB 1 ATOM 1575 C CG . LEU A 1 216 ? 41.137 49.925 0.119 1.00 6.74 ? 216 LEU A CG 1 ATOM 1576 C CD1 . LEU A 1 216 ? 39.835 49.891 0.890 1.00 7.90 ? 216 LEU A CD1 1 ATOM 1577 C CD2 . LEU A 1 216 ? 42.250 50.613 0.977 1.00 8.92 ? 216 LEU A CD2 1 ATOM 1578 N N . GLN A 1 217 ? 42.281 46.096 -2.160 1.00 6.84 ? 217 GLN A N 1 ATOM 1579 C CA . GLN A 1 217 ? 42.570 44.658 -2.311 1.00 7.26 ? 217 GLN A CA 1 ATOM 1580 C C . GLN A 1 217 ? 43.911 44.437 -2.983 1.00 7.48 ? 217 GLN A C 1 ATOM 1581 O O . GLN A 1 217 ? 44.555 43.419 -2.732 1.00 10.61 ? 217 GLN A O 1 ATOM 1582 C CB . GLN A 1 217 ? 41.380 44.045 -3.059 1.00 8.40 ? 217 GLN A CB 1 ATOM 1583 C CG . GLN A 1 217 ? 41.407 42.486 -3.133 1.00 9.74 ? 217 GLN A CG 1 ATOM 1584 C CD . GLN A 1 217 ? 42.244 41.974 -4.239 1.00 13.06 ? 217 GLN A CD 1 ATOM 1585 O OE1 . GLN A 1 217 ? 42.317 42.588 -5.295 1.00 13.08 ? 217 GLN A OE1 1 ATOM 1586 N NE2 . GLN A 1 217 ? 42.867 40.788 -4.045 1.00 15.04 ? 217 GLN A NE2 1 ATOM 1587 N N . LYS A 1 218 ? 44.371 45.372 -3.825 1.00 6.39 ? 218 LYS A N 1 ATOM 1588 C CA . LYS A 1 218 ? 45.674 45.281 -4.478 1.00 6.86 ? 218 LYS A CA 1 ATOM 1589 C C . LYS A 1 218 ? 46.806 45.878 -3.591 1.00 7.48 ? 218 LYS A C 1 ATOM 1590 O O . LYS A 1 218 ? 47.963 45.956 -4.022 1.00 7.94 ? 218 LYS A O 1 ATOM 1591 C CB . LYS A 1 218 ? 45.617 45.979 -5.816 1.00 7.87 ? 218 LYS A CB 1 ATOM 1592 C CG . LYS A 1 218 ? 44.846 45.148 -6.876 1.00 9.18 ? 218 LYS A CG 1 ATOM 1593 C CD . LYS A 1 218 ? 44.529 45.992 -8.140 1.00 9.55 ? 218 LYS A CD 1 ATOM 1594 C CE . LYS A 1 218 ? 44.139 45.164 -9.347 1.00 13.90 ? 218 LYS A CE 1 ATOM 1595 N NZ . LYS A 1 218 ? 43.070 44.135 -9.141 1.00 13.65 ? 218 LYS A NZ 1 ATOM 1596 N N . SER A 1 219 ? 46.443 46.307 -2.393 1.00 6.49 ? 219 SER A N 1 ATOM 1597 C CA . SER A 1 219 ? 47.354 46.911 -1.413 1.00 7.11 ? 219 SER A CA 1 ATOM 1598 C C . SER A 1 219 ? 47.367 46.103 -0.107 1.00 7.32 ? 219 SER A C 1 ATOM 1599 O O . SER A 1 219 ? 47.706 46.653 0.954 1.00 7.88 ? 219 SER A O 1 ATOM 1600 C CB . SER A 1 219 ? 46.973 48.386 -1.150 1.00 7.05 ? 219 SER A CB 1 ATOM 1601 O OG . SER A 1 219 ? 47.014 49.102 -2.431 1.00 7.79 ? 219 SER A OG 1 ATOM 1602 N N . GLY A 1 220 ? 46.986 44.823 -0.195 1.00 7.87 ? 220 GLY A N 1 ATOM 1603 C CA . GLY A 1 220 ? 47.035 43.932 0.972 1.00 7.96 ? 220 GLY A CA 1 ATOM 1604 C C . GLY A 1 220 ? 45.847 43.923 1.879 1.00 7.88 ? 220 GLY A C 1 ATOM 1605 O O . GLY A 1 220 ? 45.851 43.143 2.836 1.00 9.45 ? 220 GLY A O 1 ATOM 1606 N N . PHE A 1 221 ? 44.800 44.689 1.617 1.00 7.60 ? 221 PHE A N 1 ATOM 1607 C CA . PHE A 1 221 ? 43.682 44.712 2.549 1.00 6.78 ? 221 PHE A CA 1 ATOM 1608 C C . PHE A 1 221 ? 42.866 43.470 2.487 1.00 7.44 ? 221 PHE A C 1 ATOM 1609 O O . PHE A 1 221 ? 42.776 42.811 1.437 1.00 8.90 ? 221 PHE A O 1 ATOM 1610 C CB . PHE A 1 221 ? 42.791 45.942 2.269 1.00 6.62 ? 221 PHE A CB 1 ATOM 1611 C CG . PHE A 1 221 ? 43.348 47.212 2.808 1.00 5.81 ? 221 PHE A CG 1 ATOM 1612 C CD1 . PHE A 1 221 ? 44.463 47.835 2.232 1.00 6.23 ? 221 PHE A CD1 1 ATOM 1613 C CD2 . PHE A 1 221 ? 42.755 47.813 3.929 1.00 6.69 ? 221 PHE A CD2 1 ATOM 1614 C CE1 . PHE A 1 221 ? 44.986 49.026 2.776 1.00 5.64 ? 221 PHE A CE1 1 ATOM 1615 C CE2 . PHE A 1 221 ? 43.284 48.995 4.450 1.00 7.05 ? 221 PHE A CE2 1 ATOM 1616 C CZ . PHE A 1 221 ? 44.412 49.623 3.875 1.00 6.27 ? 221 PHE A CZ 1 ATOM 1617 N N . LYS A 1 222 ? 42.183 43.206 3.591 1.00 8.10 ? 222 LYS A N 1 ATOM 1618 C CA . LYS A 1 222 ? 41.281 42.049 3.726 1.00 8.13 ? 222 LYS A CA 1 ATOM 1619 C C . LYS A 1 222 ? 39.874 42.457 4.082 1.00 8.19 ? 222 LYS A C 1 ATOM 1620 O O . LYS A 1 222 ? 38.962 41.676 3.871 1.00 8.43 ? 222 LYS A O 1 ATOM 1621 C CB . LYS A 1 222 ? 41.800 41.099 4.808 1.00 11.06 ? 222 LYS A CB 1 ATOM 1622 C CG . LYS A 1 222 ? 43.196 40.533 4.509 1.00 14.19 ? 222 LYS A CG 1 ATOM 1623 C CD . LYS A 1 222 ? 43.263 39.876 3.120 1.00 23.16 ? 222 LYS A CD 1 ATOM 1624 C CE . LYS A 1 222 ? 44.422 38.838 2.916 1.00 31.14 ? 222 LYS A CE 1 ATOM 1625 N NZ . LYS A 1 222 ? 45.787 39.425 2.703 1.00 36.02 ? 222 LYS A NZ 1 ATOM 1626 N N . ASN A 1 223 ? 39.647 43.676 4.560 1.00 6.45 ? 223 ASN A N 1 ATOM 1627 C CA . ASN A 1 223 ? 38.315 44.091 5.012 1.00 6.81 ? 223 ASN A CA 1 ATOM 1628 C C . ASN A 1 223 ? 38.156 45.595 4.868 1.00 6.32 ? 223 ASN A C 1 ATOM 1629 O O . ASN A 1 223 ? 39.120 46.321 4.944 1.00 6.92 ? 223 ASN A O 1 ATOM 1630 C CB . ASN A 1 223 ? 38.122 43.720 6.494 1.00 7.30 ? 223 ASN A CB 1 ATOM 1631 C CG . ASN A 1 223 ? 38.094 42.223 6.742 1.00 8.90 ? 223 ASN A CG 1 ATOM 1632 O OD1 . ASN A 1 223 ? 37.118 41.559 6.461 1.00 11.35 ? 223 ASN A OD1 1 ATOM 1633 N ND2 . ASN A 1 223 ? 39.191 41.695 7.260 1.00 7.06 ? 223 ASN A ND2 1 ATOM 1634 N N . MET A 1 224 ? 36.916 46.045 4.708 1.00 6.49 ? 224 MET A N 1 ATOM 1635 C CA . MET A 1 224 ? 36.643 47.498 4.711 1.00 6.16 ? 224 MET A CA 1 ATOM 1636 C C . MET A 1 224 ? 35.236 47.780 5.257 1.00 6.25 ? 224 MET A C 1 ATOM 1637 O O . MET A 1 224 ? 34.352 46.891 5.242 1.00 7.34 ? 224 MET A O 1 ATOM 1638 C CB . MET A 1 224 ? 36.787 48.084 3.312 1.00 8.78 ? 224 MET A CB 1 ATOM 1639 C CG . MET A 1 224 ? 35.772 47.589 2.300 1.00 7.96 ? 224 MET A CG 1 ATOM 1640 S SD . MET A 1 224 ? 35.922 48.307 0.650 1.00 9.36 ? 224 MET A SD 1 ATOM 1641 C CE . MET A 1 224 ? 35.695 50.000 1.017 1.00 13.35 ? 224 MET A CE 1 ATOM 1642 N N . LEU A 1 225 ? 35.091 49.010 5.755 1.00 6.42 ? 225 LEU A N 1 ATOM 1643 C CA . LEU A 1 225 ? 33.823 49.446 6.309 1.00 6.23 ? 225 LEU A CA 1 ATOM 1644 C C . LEU A 1 225 ? 33.421 50.767 5.676 1.00 6.89 ? 225 LEU A C 1 ATOM 1645 O O . LEU A 1 225 ? 34.278 51.663 5.488 1.00 6.73 ? 225 LEU A O 1 ATOM 1646 C CB . LEU A 1 225 ? 33.987 49.592 7.847 1.00 7.79 ? 225 LEU A CB 1 ATOM 1647 C CG . LEU A 1 225 ? 32.785 50.223 8.580 1.00 7.16 ? 225 LEU A CG 1 ATOM 1648 C CD1 . LEU A 1 225 ? 32.700 49.616 10.000 1.00 8.55 ? 225 LEU A CD1 1 ATOM 1649 C CD2 . LEU A 1 225 ? 32.886 51.743 8.616 1.00 8.42 ? 225 LEU A CD2 1 ATOM 1650 N N . ILE A 1 226 ? 32.132 50.879 5.389 1.00 5.88 ? 226 ILE A N 1 ATOM 1651 C CA . ILE A 1 226 ? 31.535 52.109 4.815 1.00 6.60 ? 226 ILE A CA 1 ATOM 1652 C C . ILE A 1 226 ? 30.307 52.510 5.583 1.00 6.84 ? 226 ILE A C 1 ATOM 1653 O O . ILE A 1 226 ? 29.704 51.659 6.292 1.00 7.47 ? 226 ILE A O 1 ATOM 1654 C CB . ILE A 1 226 ? 31.251 51.925 3.276 1.00 6.52 ? 226 ILE A CB 1 ATOM 1655 C CG1 . ILE A 1 226 ? 30.208 50.827 3.034 1.00 6.58 ? 226 ILE A CG1 1 ATOM 1656 C CG2 . ILE A 1 226 ? 32.554 51.619 2.568 1.00 7.59 ? 226 ILE A CG2 1 ATOM 1657 C CD1 . ILE A 1 226 ? 29.797 50.705 1.549 1.00 8.92 ? 226 ILE A CD1 1 ATOM 1658 N N . GLN A 1 227 ? 29.875 53.749 5.429 1.00 7.88 ? 227 GLN A N 1 ATOM 1659 C CA . GLN A 1 227 ? 28.729 54.249 6.186 1.00 8.05 ? 227 GLN A CA 1 ATOM 1660 C C . GLN A 1 227 ? 27.719 55.072 5.374 1.00 7.78 ? 227 GLN A C 1 ATOM 1661 O O . GLN A 1 227 ? 26.502 54.831 5.515 1.00 8.56 ? 227 GLN A O 1 ATOM 1662 C CB . GLN A 1 227 ? 29.244 55.133 7.344 1.00 8.64 ? 227 GLN A CB 1 ATOM 1663 C CG . GLN A 1 227 ? 28.223 56.211 7.902 1.00 10.90 ? 227 GLN A CG 1 ATOM 1664 C CD . GLN A 1 227 ? 26.915 55.679 8.459 1.00 9.96 ? 227 GLN A CD 1 ATOM 1665 O OE1 . GLN A 1 227 ? 26.854 54.522 8.923 1.00 12.85 ? 227 GLN A OE1 1 ATOM 1666 N NE2 . GLN A 1 227 ? 25.877 56.506 8.444 1.00 11.23 ? 227 GLN A NE2 1 ATOM 1667 N N . ARG A 1 228 ? 28.145 56.041 4.564 1.00 7.18 ? 228 ARG A N 1 ATOM 1668 C CA . ARG A 1 228 ? 27.156 56.901 3.936 1.00 7.61 ? 228 ARG A CA 1 ATOM 1669 C C . ARG A 1 228 ? 26.644 56.379 2.629 1.00 7.94 ? 228 ARG A C 1 ATOM 1670 O O . ARG A 1 228 ? 27.211 56.621 1.547 1.00 8.49 ? 228 ARG A O 1 ATOM 1671 C CB . ARG A 1 228 ? 27.710 58.344 3.732 1.00 7.52 ? 228 ARG A CB 1 ATOM 1672 C CG . ARG A 1 228 ? 27.933 59.072 5.034 1.00 7.09 ? 228 ARG A CG 1 ATOM 1673 C CD . ARG A 1 228 ? 28.220 60.578 4.746 1.00 8.26 ? 228 ARG A CD 1 ATOM 1674 N NE . ARG A 1 228 ? 28.494 61.320 5.984 1.00 7.82 ? 228 ARG A NE 1 ATOM 1675 C CZ . ARG A 1 228 ? 27.560 61.790 6.804 1.00 9.96 ? 228 ARG A CZ 1 ATOM 1676 N NH1 . ARG A 1 228 ? 26.249 61.640 6.557 1.00 12.04 ? 228 ARG A NH1 1 ATOM 1677 N NH2 . ARG A 1 228 ? 27.941 62.338 7.957 1.00 11.43 ? 228 ARG A NH2 1 ATOM 1678 N N . THR A 1 229 ? 25.587 55.574 2.737 1.00 7.42 ? 229 THR A N 1 ATOM 1679 C CA . THR A 1 229 ? 24.876 55.044 1.568 1.00 6.14 ? 229 THR A CA 1 ATOM 1680 C C . THR A 1 229 ? 23.433 55.465 1.746 1.00 7.25 ? 229 THR A C 1 ATOM 1681 O O . THR A 1 229 ? 22.941 55.738 2.863 1.00 7.83 ? 229 THR A O 1 ATOM 1682 C CB . THR A 1 229 ? 24.984 53.508 1.463 1.00 8.31 ? 229 THR A CB 1 ATOM 1683 O OG1 . THR A 1 229 ? 24.360 52.938 2.623 1.00 8.84 ? 229 THR A OG1 1 ATOM 1684 C CG2 . THR A 1 229 ? 26.438 53.121 1.371 1.00 7.82 ? 229 THR A CG2 1 ATOM 1685 N N . HIS A 1 230 ? 22.720 55.548 0.630 1.00 7.77 ? 230 HIS A N 1 ATOM 1686 C CA . HIS A 1 230 ? 21.324 55.996 0.622 1.00 8.30 ? 230 HIS A CA 1 ATOM 1687 C C . HIS A 1 230 ? 20.502 55.248 1.669 1.00 7.13 ? 230 HIS A C 1 ATOM 1688 O O . HIS A 1 230 ? 20.570 54.014 1.745 1.00 8.55 ? 230 HIS A O 1 ATOM 1689 C CB . HIS A 1 230 ? 20.774 55.754 -0.783 1.00 8.87 ? 230 HIS A CB 1 ATOM 1690 C CG . HIS A 1 230 ? 19.487 56.442 -1.105 1.00 8.38 ? 230 HIS A CG 1 ATOM 1691 N ND1 . HIS A 1 230 ? 18.309 56.206 -0.407 1.00 9.03 ? 230 HIS A ND1 1 ATOM 1692 C CD2 . HIS A 1 230 ? 19.181 57.328 -2.083 1.00 10.44 ? 230 HIS A CD2 1 ATOM 1693 C CE1 . HIS A 1 230 ? 17.342 56.947 -0.937 1.00 9.25 ? 230 HIS A CE1 1 ATOM 1694 N NE2 . HIS A 1 230 ? 17.852 57.630 -1.962 1.00 8.97 ? 230 HIS A NE2 1 ATOM 1695 N N . TYR A 1 231 ? 19.669 56.001 2.403 1.00 7.52 ? 231 TYR A N 1 ATOM 1696 C CA . TYR A 1 231 ? 18.876 55.359 3.451 1.00 7.38 ? 231 TYR A CA 1 ATOM 1697 C C . TYR A 1 231 ? 18.007 54.244 2.876 1.00 9.24 ? 231 TYR A C 1 ATOM 1698 O O . TYR A 1 231 ? 17.718 53.294 3.603 1.00 9.88 ? 231 TYR A O 1 ATOM 1699 C CB . TYR A 1 231 ? 18.038 56.396 4.209 1.00 9.25 ? 231 TYR A CB 1 ATOM 1700 C CG . TYR A 1 231 ? 17.061 57.179 3.328 1.00 10.02 ? 231 TYR A CG 1 ATOM 1701 C CD1 . TYR A 1 231 ? 15.751 56.707 3.133 1.00 10.58 ? 231 TYR A CD1 1 ATOM 1702 C CD2 . TYR A 1 231 ? 17.422 58.404 2.739 1.00 8.36 ? 231 TYR A CD2 1 ATOM 1703 C CE1 . TYR A 1 231 ? 14.838 57.444 2.399 1.00 9.98 ? 231 TYR A CE1 1 ATOM 1704 C CE2 . TYR A 1 231 ? 16.503 59.155 1.976 1.00 8.81 ? 231 TYR A CE2 1 ATOM 1705 C CZ . TYR A 1 231 ? 15.211 58.647 1.829 1.00 8.88 ? 231 TYR A CZ 1 ATOM 1706 O OH . TYR A 1 231 ? 14.277 59.385 1.090 1.00 10.64 ? 231 TYR A OH 1 ATOM 1707 N N . SER A 1 232 ? 17.536 54.341 1.645 1.00 8.83 ? 232 SER A N 1 ATOM 1708 C CA . SER A 1 232 ? 16.691 53.252 1.111 1.00 9.83 ? 232 SER A CA 1 ATOM 1709 C C . SER A 1 232 ? 17.500 52.018 0.863 1.00 10.10 ? 232 SER A C 1 ATOM 1710 O O . SER A 1 232 ? 17.019 50.878 0.955 1.00 9.43 ? 232 SER A O 1 ATOM 1711 C CB . SER A 1 232 ? 16.016 53.658 -0.188 1.00 11.00 ? 232 SER A CB 1 ATOM 1712 O OG . SER A 1 232 ? 15.150 54.763 -0.001 1.00 12.86 ? 232 SER A OG 1 ATOM 1713 N N . VAL A 1 233 ? 18.775 52.204 0.479 1.00 8.50 ? 233 VAL A N 1 ATOM 1714 C CA . VAL A 1 233 ? 19.691 51.075 0.286 1.00 9.03 ? 233 VAL A CA 1 ATOM 1715 C C . VAL A 1 233 ? 19.966 50.379 1.646 1.00 8.38 ? 233 VAL A C 1 ATOM 1716 O O . VAL A 1 233 ? 19.936 49.128 1.701 1.00 9.83 ? 233 VAL A O 1 ATOM 1717 C CB . VAL A 1 233 ? 21.038 51.527 -0.378 1.00 8.58 ? 233 VAL A CB 1 ATOM 1718 C CG1 . VAL A 1 233 ? 22.040 50.370 -0.389 1.00 9.28 ? 233 VAL A CG1 1 ATOM 1719 C CG2 . VAL A 1 233 ? 20.707 51.896 -1.847 1.00 10.34 ? 233 VAL A CG2 1 ATOM 1720 N N . LYS A 1 234 ? 20.263 51.140 2.693 1.00 8.72 ? 234 LYS A N 1 ATOM 1721 C CA . LYS A 1 234 ? 20.445 50.511 4.018 1.00 9.06 ? 234 LYS A CA 1 ATOM 1722 C C . LYS A 1 234 ? 19.208 49.686 4.398 1.00 9.62 ? 234 LYS A C 1 ATOM 1723 O O . LYS A 1 234 ? 19.394 48.543 4.852 1.00 9.50 ? 234 LYS A O 1 ATOM 1724 C CB . LYS A 1 234 ? 20.664 51.607 5.042 1.00 8.14 ? 234 LYS A CB 1 ATOM 1725 C CG . LYS A 1 234 ? 22.053 52.259 4.938 1.00 9.56 ? 234 LYS A CG 1 ATOM 1726 C CD . LYS A 1 234 ? 22.094 53.539 5.722 1.00 9.40 ? 234 LYS A CD 1 ATOM 1727 C CE . LYS A 1 234 ? 23.529 54.178 5.704 1.00 9.13 ? 234 LYS A CE 1 ATOM 1728 N NZ . LYS A 1 234 ? 24.413 53.628 6.834 1.00 8.60 ? 234 LYS A NZ 1 ATOM 1729 N N . LYS A 1 235 ? 18.009 50.196 4.177 1.00 8.81 ? 235 LYS A N 1 ATOM 1730 C CA . LYS A 1 235 ? 16.799 49.460 4.546 1.00 9.02 ? 235 LYS A CA 1 ATOM 1731 C C . LYS A 1 235 ? 16.678 48.167 3.742 1.00 9.89 ? 235 LYS A C 1 ATOM 1732 O O . LYS A 1 235 ? 16.380 47.125 4.300 1.00 10.93 ? 235 LYS A O 1 ATOM 1733 C CB . LYS A 1 235 ? 15.550 50.337 4.387 1.00 11.21 ? 235 LYS A CB 1 ATOM 1734 C CG . LYS A 1 235 ? 14.245 49.647 4.812 1.00 11.74 ? 235 LYS A CG 1 ATOM 1735 C CD . LYS A 1 235 ? 13.096 50.622 4.694 1.00 13.01 ? 235 LYS A CD 1 ATOM 1736 C CE . LYS A 1 235 ? 11.776 50.037 5.187 1.00 16.32 ? 235 LYS A CE 1 ATOM 1737 N NZ . LYS A 1 235 ? 10.613 50.950 4.971 1.00 20.58 ? 235 LYS A NZ 1 ATOM 1738 N N . GLU A 1 236 ? 16.900 48.234 2.437 1.00 9.57 ? 236 GLU A N 1 ATOM 1739 C CA . GLU A 1 236 ? 16.786 47.078 1.570 1.00 11.07 ? 236 GLU A CA 1 ATOM 1740 C C . GLU A 1 236 ? 17.776 46.001 1.910 1.00 11.74 ? 236 GLU A C 1 ATOM 1741 O O . GLU A 1 236 ? 17.440 44.817 2.021 1.00 12.53 ? 236 GLU A O 1 ATOM 1742 C CB . GLU A 1 236 ? 17.004 47.554 0.112 1.00 12.83 ? 236 GLU A CB 1 ATOM 1743 C CG . GLU A 1 236 ? 16.734 46.492 -0.947 1.00 21.91 ? 236 GLU A CG 1 ATOM 1744 C CD . GLU A 1 236 ? 15.214 46.193 -1.068 1.00 30.06 ? 236 GLU A CD 1 ATOM 1745 O OE1 . GLU A 1 236 ? 14.386 47.029 -0.634 1.00 30.80 ? 236 GLU A OE1 1 ATOM 1746 O OE2 . GLU A 1 236 ? 14.872 45.136 -1.611 1.00 32.77 ? 236 GLU A OE2 1 ATOM 1747 N N . LEU A 1 237 ? 19.053 46.363 2.044 1.00 9.96 ? 237 LEU A N 1 ATOM 1748 C CA . LEU A 1 237 ? 20.081 45.396 2.360 1.00 9.15 ? 237 LEU A CA 1 ATOM 1749 C C . LEU A 1 237 ? 19.879 44.889 3.798 1.00 9.94 ? 237 LEU A C 1 ATOM 1750 O O . LEU A 1 237 ? 20.081 43.670 4.044 1.00 11.06 ? 237 LEU A O 1 ATOM 1751 C CB . LEU A 1 237 ? 21.493 45.984 2.223 1.00 8.69 ? 237 LEU A CB 1 ATOM 1752 C CG . LEU A 1 237 ? 21.818 46.428 0.758 1.00 10.26 ? 237 LEU A CG 1 ATOM 1753 C CD1 . LEU A 1 237 ? 23.264 46.986 0.782 1.00 12.86 ? 237 LEU A CD1 1 ATOM 1754 C CD2 . LEU A 1 237 ? 21.709 45.283 -0.283 1.00 12.30 ? 237 LEU A CD2 1 ATOM 1755 N N . ALA A 1 238 ? 19.454 45.723 4.726 1.00 10.30 ? 238 ALA A N 1 ATOM 1756 C CA . ALA A 1 238 ? 19.263 45.249 6.115 1.00 10.25 ? 238 ALA A CA 1 ATOM 1757 C C . ALA A 1 238 ? 18.185 44.148 6.150 1.00 11.40 ? 238 ALA A C 1 ATOM 1758 O O . ALA A 1 238 ? 18.356 43.119 6.846 1.00 12.14 ? 238 ALA A O 1 ATOM 1759 C CB . ALA A 1 238 ? 18.873 46.409 7.028 1.00 11.78 ? 238 ALA A CB 1 ATOM 1760 N N . GLN A 1 239 ? 17.127 44.315 5.377 1.00 10.72 ? 239 GLN A N 1 ATOM 1761 C CA . GLN A 1 239 ? 16.037 43.301 5.402 1.00 12.05 ? 239 GLN A CA 1 ATOM 1762 C C . GLN A 1 239 ? 16.508 41.944 4.926 1.00 14.82 ? 239 GLN A C 1 ATOM 1763 O O . GLN A 1 239 ? 15.940 40.918 5.352 1.00 16.68 ? 239 GLN A O 1 ATOM 1764 C CB . GLN A 1 239 ? 14.868 43.782 4.532 1.00 14.99 ? 239 GLN A CB 1 ATOM 1765 C CG . GLN A 1 239 ? 14.077 44.914 5.190 1.00 19.13 ? 239 GLN A CG 1 ATOM 1766 C CD . GLN A 1 239 ? 13.041 45.628 4.298 1.00 25.94 ? 239 GLN A CD 1 ATOM 1767 O OE1 . GLN A 1 239 ? 13.138 45.654 3.084 1.00 29.92 ? 239 GLN A OE1 1 ATOM 1768 N NE2 . GLN A 1 239 ? 12.055 46.254 4.942 1.00 31.64 ? 239 GLN A NE2 1 ATOM 1769 N N . GLN A 1 240 ? 17.494 41.918 4.034 1.00 11.64 ? 240 GLN A N 1 ATOM 1770 C CA . GLN A 1 240 ? 18.038 40.682 3.490 1.00 12.08 ? 240 GLN A CA 1 ATOM 1771 C C . GLN A 1 240 ? 19.300 40.221 4.210 1.00 9.98 ? 240 GLN A C 1 ATOM 1772 O O . GLN A 1 240 ? 19.889 39.260 3.828 1.00 11.24 ? 240 GLN A O 1 ATOM 1773 C CB . GLN A 1 240 ? 18.356 40.855 2.013 1.00 15.00 ? 240 GLN A CB 1 ATOM 1774 C CG . GLN A 1 240 ? 17.201 41.361 1.196 1.00 21.01 ? 240 GLN A CG 1 ATOM 1775 C CD . GLN A 1 240 ? 16.040 40.412 1.238 1.00 26.56 ? 240 GLN A CD 1 ATOM 1776 O OE1 . GLN A 1 240 ? 16.199 39.198 1.223 1.00 32.34 ? 240 GLN A OE1 1 ATOM 1777 N NE2 . GLN A 1 240 ? 14.854 40.970 1.301 1.00 25.34 ? 240 GLN A NE2 1 ATOM 1778 N N . ARG A 1 241 ? 19.707 40.946 5.240 1.00 10.08 ? 241 ARG A N 1 ATOM 1779 C CA . ARG A 1 241 ? 20.997 40.717 5.916 1.00 10.70 ? 241 ARG A CA 1 ATOM 1780 C C . ARG A 1 241 ? 22.131 40.693 4.907 1.00 10.32 ? 241 ARG A C 1 ATOM 1781 O O . ARG A 1 241 ? 22.981 39.785 4.850 1.00 9.94 ? 241 ARG A O 1 ATOM 1782 C CB . ARG A 1 241 ? 21.036 39.412 6.748 1.00 11.23 ? 241 ARG A CB 1 ATOM 1783 C CG . ARG A 1 241 ? 19.970 39.485 7.868 1.00 13.26 ? 241 ARG A CG 1 ATOM 1784 C CD . ARG A 1 241 ? 20.070 38.346 8.906 1.00 13.40 ? 241 ARG A CD 1 ATOM 1785 N NE . ARG A 1 241 ? 20.108 37.044 8.265 1.00 20.16 ? 241 ARG A NE 1 ATOM 1786 C CZ . ARG A 1 241 ? 20.556 35.942 8.872 1.00 18.98 ? 241 ARG A CZ 1 ATOM 1787 N NH1 . ARG A 1 241 ? 20.977 36.005 10.143 1.00 20.54 ? 241 ARG A NH1 1 ATOM 1788 N NH2 . ARG A 1 241 ? 20.647 34.788 8.201 1.00 24.65 ? 241 ARG A NH2 1 ATOM 1789 N N . GLN A 1 242 ? 22.136 41.740 4.052 1.00 9.08 ? 242 GLN A N 1 ATOM 1790 C CA . GLN A 1 242 ? 23.172 41.878 2.986 1.00 8.82 ? 242 GLN A CA 1 ATOM 1791 C C . GLN A 1 242 ? 24.030 43.113 3.244 1.00 9.04 ? 242 GLN A C 1 ATOM 1792 O O . GLN A 1 242 ? 24.573 43.660 2.281 1.00 10.23 ? 242 GLN A O 1 ATOM 1793 C CB . GLN A 1 242 ? 22.481 41.961 1.606 1.00 8.96 ? 242 GLN A CB 1 ATOM 1794 C CG . GLN A 1 242 ? 21.898 40.590 1.179 1.00 11.40 ? 242 GLN A CG 1 ATOM 1795 C CD . GLN A 1 242 ? 21.028 40.699 -0.079 1.00 11.27 ? 242 GLN A CD 1 ATOM 1796 O OE1 . GLN A 1 242 ? 20.494 41.757 -0.363 1.00 12.88 ? 242 GLN A OE1 1 ATOM 1797 N NE2 . GLN A 1 242 ? 20.948 39.599 -0.846 1.00 13.84 ? 242 GLN A NE2 1 ATOM 1798 N N . LEU A 1 243 ? 24.112 43.537 4.512 1.00 8.09 ? 243 LEU A N 1 ATOM 1799 C CA . LEU A 1 243 ? 24.977 44.682 4.857 1.00 6.90 ? 243 LEU A CA 1 ATOM 1800 C C . LEU A 1 243 ? 26.443 44.293 4.910 1.00 7.28 ? 243 LEU A C 1 ATOM 1801 O O . LEU A 1 243 ? 27.307 45.198 4.907 1.00 9.53 ? 243 LEU A O 1 ATOM 1802 C CB . LEU A 1 243 ? 24.522 45.258 6.185 1.00 8.17 ? 243 LEU A CB 1 ATOM 1803 C CG . LEU A 1 243 ? 23.135 45.898 6.135 1.00 9.83 ? 243 LEU A CG 1 ATOM 1804 C CD1 . LEU A 1 243 ? 22.666 46.098 7.593 1.00 11.49 ? 243 LEU A CD1 1 ATOM 1805 C CD2 . LEU A 1 243 ? 23.133 47.296 5.448 1.00 10.93 ? 243 LEU A CD2 1 ATOM 1806 N N . GLU A 1 244 ? 26.775 43.005 4.973 1.00 7.34 ? 244 GLU A N 1 ATOM 1807 C CA . GLU A 1 244 ? 28.152 42.556 4.837 1.00 7.38 ? 244 GLU A CA 1 ATOM 1808 C C . GLU A 1 244 ? 28.160 41.769 3.560 1.00 7.73 ? 244 GLU A C 1 ATOM 1809 O O . GLU A 1 244 ? 27.341 40.833 3.338 1.00 8.85 ? 244 GLU A O 1 ATOM 1810 C CB . GLU A 1 244 ? 28.630 41.689 6.025 1.00 7.52 ? 244 GLU A CB 1 ATOM 1811 C CG . GLU A 1 244 ? 28.943 42.603 7.239 1.00 9.22 ? 244 GLU A CG 1 ATOM 1812 C CD . GLU A 1 244 ? 29.251 41.929 8.552 1.00 9.59 ? 244 GLU A CD 1 ATOM 1813 O OE1 . GLU A 1 244 ? 28.662 40.849 8.842 1.00 9.88 ? 244 GLU A OE1 1 ATOM 1814 O OE2 . GLU A 1 244 ? 30.086 42.495 9.310 1.00 9.76 ? 244 GLU A OE2 1 ATOM 1815 N N . PHE A 1 245 ? 29.127 42.053 2.695 1.00 7.67 ? 245 PHE A N 1 ATOM 1816 C CA . PHE A 1 245 ? 29.168 41.436 1.370 1.00 6.85 ? 245 PHE A CA 1 ATOM 1817 C C . PHE A 1 245 ? 30.571 41.409 0.810 1.00 6.98 ? 245 PHE A C 1 ATOM 1818 O O . PHE A 1 245 ? 31.453 42.162 1.262 1.00 8.27 ? 245 PHE A O 1 ATOM 1819 C CB . PHE A 1 245 ? 28.210 42.204 0.387 1.00 7.38 ? 245 PHE A CB 1 ATOM 1820 C CG . PHE A 1 245 ? 28.361 43.713 0.442 1.00 6.04 ? 245 PHE A CG 1 ATOM 1821 C CD1 . PHE A 1 245 ? 29.341 44.348 -0.376 1.00 6.41 ? 245 PHE A CD1 1 ATOM 1822 C CD2 . PHE A 1 245 ? 27.575 44.467 1.287 1.00 7.77 ? 245 PHE A CD2 1 ATOM 1823 C CE1 . PHE A 1 245 ? 29.501 45.751 -0.334 1.00 6.93 ? 245 PHE A CE1 1 ATOM 1824 C CE2 . PHE A 1 245 ? 27.726 45.881 1.335 1.00 8.21 ? 245 PHE A CE2 1 ATOM 1825 C CZ . PHE A 1 245 ? 28.691 46.485 0.509 1.00 6.94 ? 245 PHE A CZ 1 ATOM 1826 N N . LEU A 1 246 ? 30.813 40.565 -0.180 1.00 6.91 ? 246 LEU A N 1 ATOM 1827 C CA . LEU A 1 246 ? 32.092 40.486 -0.858 1.00 6.49 ? 246 LEU A CA 1 ATOM 1828 C C . LEU A 1 246 ? 31.950 41.397 -2.078 1.00 6.56 ? 246 LEU A C 1 ATOM 1829 O O . LEU A 1 246 ? 31.267 41.073 -3.066 1.00 7.68 ? 246 LEU A O 1 ATOM 1830 C CB . LEU A 1 246 ? 32.369 39.028 -1.260 1.00 9.31 ? 246 LEU A CB 1 ATOM 1831 C CG . LEU A 1 246 ? 32.666 38.135 -0.014 1.00 10.58 ? 246 LEU A CG 1 ATOM 1832 C CD1 . LEU A 1 246 ? 32.582 36.634 -0.485 1.00 16.38 ? 246 LEU A CD1 1 ATOM 1833 C CD2 . LEU A 1 246 ? 34.074 38.443 0.451 1.00 15.71 ? 246 LEU A CD2 1 ATOM 1834 N N . TRP A 1 247 ? 32.577 42.581 -1.990 1.00 6.88 ? 247 TRP A N 1 ATOM 1835 C CA . TRP A 1 247 ? 32.408 43.601 -3.013 1.00 6.14 ? 247 TRP A CA 1 ATOM 1836 C C . TRP A 1 247 ? 33.428 43.400 -4.104 1.00 6.45 ? 247 TRP A C 1 ATOM 1837 O O . TRP A 1 247 ? 34.621 43.568 -3.876 1.00 6.88 ? 247 TRP A O 1 ATOM 1838 C CB . TRP A 1 247 ? 32.579 44.965 -2.339 1.00 6.34 ? 247 TRP A CB 1 ATOM 1839 C CG . TRP A 1 247 ? 32.105 46.144 -3.184 1.00 6.25 ? 247 TRP A CG 1 ATOM 1840 C CD1 . TRP A 1 247 ? 31.582 46.144 -4.465 1.00 6.64 ? 247 TRP A CD1 1 ATOM 1841 C CD2 . TRP A 1 247 ? 32.127 47.518 -2.763 1.00 6.68 ? 247 TRP A CD2 1 ATOM 1842 N NE1 . TRP A 1 247 ? 31.246 47.441 -4.844 1.00 7.00 ? 247 TRP A NE1 1 ATOM 1843 C CE2 . TRP A 1 247 ? 31.570 48.291 -3.818 1.00 6.14 ? 247 TRP A CE2 1 ATOM 1844 C CE3 . TRP A 1 247 ? 32.564 48.167 -1.578 1.00 6.79 ? 247 TRP A CE3 1 ATOM 1845 C CZ2 . TRP A 1 247 ? 31.441 49.701 -3.728 1.00 7.24 ? 247 TRP A CZ2 1 ATOM 1846 C CZ3 . TRP A 1 247 ? 32.435 49.554 -1.516 1.00 6.38 ? 247 TRP A CZ3 1 ATOM 1847 C CH2 . TRP A 1 247 ? 31.890 50.307 -2.559 1.00 6.48 ? 247 TRP A CH2 1 ATOM 1848 N N . ARG A 1 248 ? 32.943 43.015 -5.305 1.00 6.52 ? 248 ARG A N 1 ATOM 1849 C CA . ARG A 1 248 ? 33.813 42.817 -6.451 1.00 6.87 ? 248 ARG A CA 1 ATOM 1850 C C . ARG A 1 248 ? 33.539 43.887 -7.509 1.00 6.96 ? 248 ARG A C 1 ATOM 1851 O O . ARG A 1 248 ? 32.493 44.542 -7.471 1.00 7.27 ? 248 ARG A O 1 ATOM 1852 C CB . ARG A 1 248 ? 33.602 41.433 -7.134 1.00 7.88 ? 248 ARG A CB 1 ATOM 1853 C CG . ARG A 1 248 ? 32.204 41.264 -7.771 1.00 7.69 ? 248 ARG A CG 1 ATOM 1854 C CD . ARG A 1 248 ? 32.169 39.973 -8.629 1.00 10.20 ? 248 ARG A CD 1 ATOM 1855 N NE . ARG A 1 248 ? 32.239 38.812 -7.713 1.00 10.98 ? 248 ARG A NE 1 ATOM 1856 C CZ . ARG A 1 248 ? 32.150 37.562 -8.156 1.00 13.96 ? 248 ARG A CZ 1 ATOM 1857 N NH1 . ARG A 1 248 ? 32.033 37.336 -9.475 1.00 14.16 ? 248 ARG A NH1 1 ATOM 1858 N NH2 . ARG A 1 248 ? 32.081 36.546 -7.289 1.00 14.33 ? 248 ARG A NH2 1 ATOM 1859 N N . GLN A 1 249 ? 34.469 44.055 -8.431 1.00 7.12 ? 249 GLN A N 1 ATOM 1860 C CA . GLN A 1 249 ? 34.295 44.981 -9.536 1.00 5.93 ? 249 GLN A CA 1 ATOM 1861 C C . GLN A 1 249 ? 33.204 44.548 -10.514 1.00 7.37 ? 249 GLN A C 1 ATOM 1862 O O . GLN A 1 249 ? 32.934 43.372 -10.697 1.00 8.37 ? 249 GLN A O 1 ATOM 1863 C CB . GLN A 1 249 ? 35.626 45.171 -10.268 1.00 8.04 ? 249 GLN A CB 1 ATOM 1864 C CG . GLN A 1 249 ? 36.724 45.742 -9.349 1.00 7.45 ? 249 GLN A CG 1 ATOM 1865 C CD . GLN A 1 249 ? 36.321 47.043 -8.684 1.00 7.40 ? 249 GLN A CD 1 ATOM 1866 O OE1 . GLN A 1 249 ? 36.054 48.010 -9.361 1.00 9.62 ? 249 GLN A OE1 1 ATOM 1867 N NE2 . GLN A 1 249 ? 36.300 47.064 -7.374 1.00 5.91 ? 249 GLN A NE2 1 ATOM 1868 N N . ILE A 1 250 ? 32.605 45.535 -11.160 1.00 7.84 ? 250 ILE A N 1 ATOM 1869 C CA . ILE A 1 250 ? 31.436 45.259 -11.998 1.00 8.41 ? 250 ILE A CA 1 ATOM 1870 C C . ILE A 1 250 ? 31.733 44.324 -13.166 1.00 8.90 ? 250 ILE A C 1 ATOM 1871 O O . ILE A 1 250 ? 30.822 43.685 -13.674 1.00 9.42 ? 250 ILE A O 1 ATOM 1872 C CB . ILE A 1 250 ? 30.742 46.560 -12.493 1.00 9.21 ? 250 ILE A CB 1 ATOM 1873 C CG1 . ILE A 1 250 ? 31.694 47.449 -13.299 1.00 9.07 ? 250 ILE A CG1 1 ATOM 1874 C CG2 . ILE A 1 250 ? 30.085 47.299 -11.338 1.00 9.93 ? 250 ILE A CG2 1 ATOM 1875 C CD1 . ILE A 1 250 ? 31.053 48.775 -13.766 1.00 10.67 ? 250 ILE A CD1 1 ATOM 1876 N N . TRP A 1 251 ? 32.990 44.258 -13.601 1.00 9.59 ? 251 TRP A N 1 ATOM 1877 C CA . TRP A 1 251 ? 33.318 43.396 -14.758 1.00 9.68 ? 251 TRP A CA 1 ATOM 1878 C C . TRP A 1 251 ? 33.956 42.084 -14.341 1.00 14.66 ? 251 TRP A C 1 ATOM 1879 O O . TRP A 1 251 ? 34.288 41.247 -15.200 1.00 14.87 ? 251 TRP A O 1 ATOM 1880 C CB . TRP A 1 251 ? 34.304 44.122 -15.665 1.00 12.08 ? 251 TRP A CB 1 ATOM 1881 C CG . TRP A 1 251 ? 35.551 44.274 -14.965 1.00 15.64 ? 251 TRP A CG 1 ATOM 1882 C CD1 . TRP A 1 251 ? 36.523 43.293 -14.769 1.00 16.89 ? 251 TRP A CD1 1 ATOM 1883 C CD2 . TRP A 1 251 ? 35.982 45.400 -14.249 1.00 13.41 ? 251 TRP A CD2 1 ATOM 1884 N NE1 . TRP A 1 251 ? 37.489 43.768 -13.995 1.00 14.77 ? 251 TRP A NE1 1 ATOM 1885 C CE2 . TRP A 1 251 ? 37.213 45.062 -13.642 1.00 12.52 ? 251 TRP A CE2 1 ATOM 1886 C CE3 . TRP A 1 251 ? 35.446 46.659 -14.032 1.00 13.03 ? 251 TRP A CE3 1 ATOM 1887 C CZ2 . TRP A 1 251 ? 37.925 45.941 -12.828 1.00 14.15 ? 251 TRP A CZ2 1 ATOM 1888 C CZ3 . TRP A 1 251 ? 36.147 47.542 -13.217 1.00 15.46 ? 251 TRP A CZ3 1 ATOM 1889 C CH2 . TRP A 1 251 ? 37.376 47.176 -12.630 1.00 17.10 ? 251 TRP A CH2 1 ATOM 1890 N N . ASP A 1 252 ? 34.117 41.867 -13.039 1.00 11.49 ? 252 ASP A N 1 ATOM 1891 C CA . ASP A 1 252 ? 34.842 40.689 -12.533 1.00 12.66 ? 252 ASP A CA 1 ATOM 1892 C C . ASP A 1 252 ? 34.034 39.429 -12.414 1.00 11.60 ? 252 ASP A C 1 ATOM 1893 O O . ASP A 1 252 ? 33.295 39.217 -11.480 1.00 13.34 ? 252 ASP A O 1 ATOM 1894 C CB . ASP A 1 252 ? 35.462 41.100 -11.200 1.00 10.38 ? 252 ASP A CB 1 ATOM 1895 C CG . ASP A 1 252 ? 36.236 39.952 -10.530 1.00 13.57 ? 252 ASP A CG 1 ATOM 1896 O OD1 . ASP A 1 252 ? 36.519 38.923 -11.218 1.00 16.86 ? 252 ASP A OD1 1 ATOM 1897 O OD2 . ASP A 1 252 ? 36.550 40.070 -9.337 1.00 13.55 ? 252 ASP A OD2 1 ATOM 1898 N N . ASN A 1 253 ? 34.178 38.589 -13.422 1.00 14.41 ? 253 ASN A N 1 ATOM 1899 C CA . ASN A 1 253 ? 33.442 37.350 -13.506 1.00 14.17 ? 253 ASN A CA 1 ATOM 1900 C C . ASN A 1 253 ? 33.871 36.323 -12.464 1.00 14.30 ? 253 ASN A C 1 ATOM 1901 O O . ASN A 1 253 ? 33.062 35.622 -11.907 1.00 17.20 ? 253 ASN A O 1 ATOM 1902 C CB . ASN A 1 253 ? 33.585 36.757 -14.916 1.00 16.19 ? 253 ASN A CB 1 ATOM 1903 C CG . ASN A 1 253 ? 32.729 35.543 -15.117 1.00 25.96 ? 253 ASN A CG 1 ATOM 1904 O OD1 . ASN A 1 253 ? 31.523 35.581 -14.933 1.00 32.08 ? 253 ASN A OD1 1 ATOM 1905 N ND2 . ASN A 1 253 ? 33.359 34.450 -15.491 1.00 22.24 ? 253 ASN A ND2 1 ATOM 1906 N N . LYS A 1 254 ? 35.157 36.243 -12.221 1.00 15.06 ? 254 LYS A N 1 ATOM 1907 C CA . LYS A 1 254 ? 35.671 35.207 -11.300 1.00 20.09 ? 254 LYS A CA 1 ATOM 1908 C C . LYS A 1 254 ? 35.559 35.581 -9.843 1.00 20.35 ? 254 LYS A C 1 ATOM 1909 O O . LYS A 1 254 ? 35.329 34.704 -8.997 1.00 21.07 ? 254 LYS A O 1 ATOM 1910 C CB . LYS A 1 254 ? 37.135 34.911 -11.631 1.00 23.90 ? 254 LYS A CB 1 ATOM 1911 C CG . LYS A 1 254 ? 37.754 33.717 -10.886 1.00 31.15 ? 254 LYS A CG 1 ATOM 1912 C CD . LYS A 1 254 ? 39.168 33.423 -11.442 1.00 35.30 ? 254 LYS A CD 1 ATOM 1913 C CE . LYS A 1 254 ? 39.823 32.185 -10.788 1.00 37.21 ? 254 LYS A CE 1 ATOM 1914 N NZ . LYS A 1 254 ? 39.551 32.090 -9.330 1.00 39.77 ? 254 LYS A NZ 1 ATOM 1915 N N . GLY A 1 255 ? 35.741 36.870 -9.541 1.00 16.91 ? 255 GLY A N 1 ATOM 1916 C CA . GLY A 1 255 ? 35.654 37.297 -8.159 1.00 15.68 ? 255 GLY A CA 1 ATOM 1917 C C . GLY A 1 255 ? 37.020 37.559 -7.529 1.00 14.38 ? 255 GLY A C 1 ATOM 1918 O O . GLY A 1 255 ? 37.030 37.833 -6.325 1.00 14.84 ? 255 GLY A O 1 ATOM 1919 N N . ASP A 1 256 ? 38.121 37.581 -8.276 1.00 15.08 ? 256 ASP A N 1 ATOM 1920 C CA . ASP A 1 256 ? 39.432 37.810 -7.651 1.00 18.93 ? 256 ASP A CA 1 ATOM 1921 C C . ASP A 1 256 ? 39.651 39.219 -7.074 1.00 16.79 ? 256 ASP A C 1 ATOM 1922 O O . ASP A 1 256 ? 40.533 39.434 -6.261 1.00 16.03 ? 256 ASP A O 1 ATOM 1923 C CB . ASP A 1 256 ? 40.579 37.503 -8.620 1.00 26.21 ? 256 ASP A CB 1 ATOM 1924 C CG . ASP A 1 256 ? 40.629 36.027 -9.040 1.00 37.03 ? 256 ASP A CG 1 ATOM 1925 O OD1 . ASP A 1 256 ? 40.175 35.162 -8.246 1.00 36.40 ? 256 ASP A OD1 1 ATOM 1926 O OD2 . ASP A 1 256 ? 41.139 35.753 -10.158 1.00 37.78 ? 256 ASP A OD2 1 ATOM 1927 N N . THR A 1 257 ? 38.824 40.184 -7.473 1.00 12.21 ? 257 THR A N 1 ATOM 1928 C CA . THR A 1 257 ? 38.932 41.533 -6.921 1.00 11.40 ? 257 THR A CA 1 ATOM 1929 C C . THR A 1 257 ? 38.130 41.686 -5.622 1.00 11.41 ? 257 THR A C 1 ATOM 1930 O O . THR A 1 257 ? 38.204 42.746 -5.005 1.00 11.36 ? 257 THR A O 1 ATOM 1931 C CB . THR A 1 257 ? 38.356 42.604 -7.926 1.00 10.59 ? 257 THR A CB 1 ATOM 1932 O OG1 . THR A 1 257 ? 36.938 42.391 -8.133 1.00 10.35 ? 257 THR A OG1 1 ATOM 1933 C CG2 . THR A 1 257 ? 39.151 42.573 -9.237 1.00 13.22 ? 257 THR A CG2 1 ATOM 1934 N N . ALA A 1 258 ? 37.367 40.661 -5.209 1.00 10.58 ? 258 ALA A N 1 ATOM 1935 C CA . ALA A 1 258 ? 36.490 40.824 -4.057 1.00 9.78 ? 258 ALA A CA 1 ATOM 1936 C C . ALA A 1 258 ? 37.125 41.195 -2.753 1.00 9.31 ? 258 ALA A C 1 ATOM 1937 O O . ALA A 1 258 ? 38.220 40.696 -2.422 1.00 10.57 ? 258 ALA A O 1 ATOM 1938 C CB . ALA A 1 258 ? 35.662 39.578 -3.821 1.00 11.64 ? 258 ALA A CB 1 ATOM 1939 N N . LEU A 1 259 ? 36.475 42.121 -2.033 1.00 7.89 ? 259 LEU A N 1 ATOM 1940 C CA . LEU A 1 259 ? 36.949 42.535 -0.694 1.00 7.43 ? 259 LEU A CA 1 ATOM 1941 C C . LEU A 1 259 ? 35.753 42.530 0.227 1.00 7.22 ? 259 LEU A C 1 ATOM 1942 O O . LEU A 1 259 ? 34.709 43.150 -0.053 1.00 7.52 ? 259 LEU A O 1 ATOM 1943 C CB . LEU A 1 259 ? 37.546 43.942 -0.765 1.00 7.28 ? 259 LEU A CB 1 ATOM 1944 C CG . LEU A 1 259 ? 38.295 44.366 0.519 1.00 7.31 ? 259 LEU A CG 1 ATOM 1945 C CD1 . LEU A 1 259 ? 39.558 43.469 0.822 1.00 11.65 ? 259 LEU A CD1 1 ATOM 1946 C CD2 . LEU A 1 259 ? 38.779 45.839 0.352 1.00 9.73 ? 259 LEU A CD2 1 ATOM 1947 N N . PHE A 1 260 ? 35.911 41.889 1.402 1.00 6.97 ? 260 PHE A N 1 ATOM 1948 C CA . PHE A 1 260 ? 34.832 41.868 2.379 1.00 6.58 ? 260 PHE A CA 1 ATOM 1949 C C . PHE A 1 260 ? 34.531 43.262 2.873 1.00 6.23 ? 260 PHE A C 1 ATOM 1950 O O . PHE A 1 260 ? 35.436 44.004 3.300 1.00 6.98 ? 260 PHE A O 1 ATOM 1951 C CB . PHE A 1 260 ? 35.250 40.951 3.573 1.00 8.24 ? 260 PHE A CB 1 ATOM 1952 C CG . PHE A 1 260 ? 34.152 40.799 4.593 1.00 7.53 ? 260 PHE A CG 1 ATOM 1953 C CD1 . PHE A 1 260 ? 33.163 39.847 4.375 1.00 10.88 ? 260 PHE A CD1 1 ATOM 1954 C CD2 . PHE A 1 260 ? 34.062 41.580 5.720 1.00 8.14 ? 260 PHE A CD2 1 ATOM 1955 C CE1 . PHE A 1 260 ? 32.090 39.689 5.290 1.00 11.34 ? 260 PHE A CE1 1 ATOM 1956 C CE2 . PHE A 1 260 ? 32.993 41.443 6.669 1.00 9.57 ? 260 PHE A CE2 1 ATOM 1957 C CZ . PHE A 1 260 ? 32.016 40.487 6.433 1.00 9.87 ? 260 PHE A CZ 1 ATOM 1958 N N . THR A 1 261 ? 33.253 43.611 2.839 1.00 6.02 ? 261 THR A N 1 ATOM 1959 C CA . THR A 1 261 ? 32.838 44.949 3.170 1.00 5.99 ? 261 THR A CA 1 ATOM 1960 C C . THR A 1 261 ? 31.696 44.916 4.199 1.00 6.86 ? 261 THR A C 1 ATOM 1961 O O . THR A 1 261 ? 30.729 44.167 4.015 1.00 7.10 ? 261 THR A O 1 ATOM 1962 C CB . THR A 1 261 ? 32.302 45.664 1.878 1.00 6.54 ? 261 THR A CB 1 ATOM 1963 O OG1 . THR A 1 261 ? 33.367 45.760 0.949 1.00 7.26 ? 261 THR A OG1 1 ATOM 1964 C CG2 . THR A 1 261 ? 31.840 47.085 2.169 1.00 7.94 ? 261 THR A CG2 1 ATOM 1965 N N . HIS A 1 262 ? 31.776 45.789 5.202 1.00 6.32 ? 262 HIS A N 1 ATOM 1966 C CA . HIS A 1 262 ? 30.732 45.970 6.182 1.00 6.57 ? 262 HIS A CA 1 ATOM 1967 C C . HIS A 1 262 ? 30.110 47.362 5.990 1.00 7.03 ? 262 HIS A C 1 ATOM 1968 O O . HIS A 1 262 ? 30.817 48.371 6.168 1.00 7.36 ? 262 HIS A O 1 ATOM 1969 C CB . HIS A 1 262 ? 31.366 45.895 7.589 1.00 7.86 ? 262 HIS A CB 1 ATOM 1970 C CG . HIS A 1 262 ? 30.404 46.239 8.695 1.00 6.39 ? 262 HIS A CG 1 ATOM 1971 N ND1 . HIS A 1 262 ? 29.819 45.272 9.493 1.00 8.93 ? 262 HIS A ND1 1 ATOM 1972 C CD2 . HIS A 1 262 ? 29.949 47.436 9.148 1.00 6.65 ? 262 HIS A CD2 1 ATOM 1973 C CE1 . HIS A 1 262 ? 29.071 45.872 10.419 1.00 9.03 ? 262 HIS A CE1 1 ATOM 1974 N NE2 . HIS A 1 262 ? 29.119 47.181 10.233 1.00 8.94 ? 262 HIS A NE2 1 ATOM 1975 N N . MET A 1 263 ? 28.842 47.427 5.652 1.00 6.30 ? 263 MET A N 1 ATOM 1976 C CA . MET A 1 263 ? 28.111 48.658 5.581 1.00 6.03 ? 263 MET A CA 1 ATOM 1977 C C . MET A 1 263 ? 27.371 48.870 6.938 1.00 7.81 ? 263 MET A C 1 ATOM 1978 O O . MET A 1 263 ? 26.614 47.945 7.378 1.00 8.47 ? 263 MET A O 1 ATOM 1979 C CB . MET A 1 263 ? 27.094 48.610 4.428 1.00 7.87 ? 263 MET A CB 1 ATOM 1980 C CG . MET A 1 263 ? 26.304 49.923 4.308 1.00 7.81 ? 263 MET A CG 1 ATOM 1981 S SD . MET A 1 263 ? 24.941 49.783 3.098 1.00 8.63 ? 263 MET A SD 1 ATOM 1982 C CE . MET A 1 263 ? 25.773 49.359 1.522 1.00 10.21 ? 263 MET A CE 1 ATOM 1983 N N . MET A 1 264 ? 27.578 50.000 7.593 1.00 7.41 ? 264 MET A N 1 ATOM 1984 C CA . MET A 1 264 ? 26.855 50.283 8.823 1.00 6.95 ? 264 MET A CA 1 ATOM 1985 C C . MET A 1 264 ? 25.389 50.572 8.473 1.00 7.57 ? 264 MET A C 1 ATOM 1986 O O . MET A 1 264 ? 25.090 51.004 7.370 1.00 8.24 ? 264 MET A O 1 ATOM 1987 C CB . MET A 1 264 ? 27.497 51.467 9.551 1.00 8.77 ? 264 MET A CB 1 ATOM 1988 C CG A MET A 1 264 ? 28.988 51.290 9.902 0.50 8.26 ? 264 MET A CG 1 ATOM 1989 C CG B MET A 1 264 ? 28.853 50.901 10.007 0.50 8.16 ? 264 MET A CG 1 ATOM 1990 S SD A MET A 1 264 ? 29.922 52.799 10.359 0.50 16.94 ? 264 MET A SD 1 ATOM 1991 S SD B MET A 1 264 ? 29.580 51.769 11.411 0.50 32.26 ? 264 MET A SD 1 ATOM 1992 C CE A MET A 1 264 ? 28.851 53.543 11.572 0.50 14.92 ? 264 MET A CE 1 ATOM 1993 C CE B MET A 1 264 ? 29.978 53.132 10.407 0.50 22.78 ? 264 MET A CE 1 ATOM 1994 N N . PRO A 1 265 ? 24.471 50.289 9.391 1.00 7.21 ? 265 PRO A N 1 ATOM 1995 C CA . PRO A 1 265 ? 23.043 50.265 9.012 1.00 7.63 ? 265 PRO A CA 1 ATOM 1996 C C . PRO A 1 265 ? 22.258 51.570 9.197 1.00 8.53 ? 265 PRO A C 1 ATOM 1997 O O . PRO A 1 265 ? 21.185 51.680 8.625 1.00 9.11 ? 265 PRO A O 1 ATOM 1998 C CB . PRO A 1 265 ? 22.455 49.184 9.924 1.00 9.82 ? 265 PRO A CB 1 ATOM 1999 C CG . PRO A 1 265 ? 23.313 49.192 11.114 1.00 11.61 ? 265 PRO A CG 1 ATOM 2000 C CD . PRO A 1 265 ? 24.693 49.695 10.720 1.00 8.40 ? 265 PRO A CD 1 ATOM 2001 N N . PHE A 1 266 ? 22.781 52.509 9.965 1.00 8.26 ? 266 PHE A N 1 ATOM 2002 C CA . PHE A 1 266 ? 22.008 53.630 10.406 1.00 8.48 ? 266 PHE A CA 1 ATOM 2003 C C . PHE A 1 266 ? 22.385 54.974 9.827 1.00 8.11 ? 266 PHE A C 1 ATOM 2004 O O . PHE A 1 266 ? 23.256 55.081 8.971 1.00 8.11 ? 266 PHE A O 1 ATOM 2005 C CB . PHE A 1 266 ? 21.968 53.605 11.945 1.00 8.58 ? 266 PHE A CB 1 ATOM 2006 C CG . PHE A 1 266 ? 21.413 52.291 12.555 1.00 8.17 ? 266 PHE A CG 1 ATOM 2007 C CD1 . PHE A 1 266 ? 20.245 51.715 12.090 1.00 10.00 ? 266 PHE A CD1 1 ATOM 2008 C CD2 . PHE A 1 266 ? 22.102 51.673 13.590 1.00 9.39 ? 266 PHE A CD2 1 ATOM 2009 C CE1 . PHE A 1 266 ? 19.757 50.488 12.680 1.00 9.58 ? 266 PHE A CE1 1 ATOM 2010 C CE2 . PHE A 1 266 ? 21.623 50.471 14.169 1.00 9.24 ? 266 PHE A CE2 1 ATOM 2011 C CZ . PHE A 1 266 ? 20.465 49.900 13.704 1.00 9.21 ? 266 PHE A CZ 1 ATOM 2012 N N . TYR A 1 267 ? 21.798 56.039 10.329 1.00 7.88 ? 267 TYR A N 1 ATOM 2013 C CA . TYR A 1 267 ? 21.826 57.343 9.668 1.00 7.62 ? 267 TYR A CA 1 ATOM 2014 C C . TYR A 1 267 ? 23.172 58.049 9.854 1.00 8.74 ? 267 TYR A C 1 ATOM 2015 O O . TYR A 1 267 ? 23.553 58.845 9.027 1.00 8.46 ? 267 TYR A O 1 ATOM 2016 C CB . TYR A 1 267 ? 20.655 58.186 10.198 1.00 9.22 ? 267 TYR A CB 1 ATOM 2017 C CG . TYR A 1 267 ? 20.705 59.678 10.015 1.00 8.76 ? 267 TYR A CG 1 ATOM 2018 C CD1 . TYR A 1 267 ? 20.295 60.279 8.830 1.00 11.08 ? 267 TYR A CD1 1 ATOM 2019 C CD2 . TYR A 1 267 ? 21.096 60.492 11.056 1.00 10.79 ? 267 TYR A CD2 1 ATOM 2020 C CE1 . TYR A 1 267 ? 20.307 61.655 8.706 1.00 12.37 ? 267 TYR A CE1 1 ATOM 2021 C CE2 . TYR A 1 267 ? 21.128 61.848 10.922 1.00 11.36 ? 267 TYR A CE2 1 ATOM 2022 C CZ . TYR A 1 267 ? 20.730 62.420 9.761 1.00 13.19 ? 267 TYR A CZ 1 ATOM 2023 O OH . TYR A 1 267 ? 20.751 63.791 9.714 1.00 17.75 ? 267 TYR A OH 1 ATOM 2024 N N . SER A 1 268 ? 23.888 57.727 10.924 1.00 8.07 ? 268 SER A N 1 ATOM 2025 C CA . SER A 1 268 ? 25.165 58.423 11.201 1.00 9.04 ? 268 SER A CA 1 ATOM 2026 C C . SER A 1 268 ? 26.128 57.475 11.888 1.00 8.17 ? 268 SER A C 1 ATOM 2027 O O . SER A 1 268 ? 25.738 56.368 12.345 1.00 8.77 ? 268 SER A O 1 ATOM 2028 C CB . SER A 1 268 ? 24.864 59.603 12.136 1.00 8.74 ? 268 SER A CB 1 ATOM 2029 O OG . SER A 1 268 ? 26.046 60.263 12.582 1.00 11.26 ? 268 SER A OG 1 ATOM 2030 N N . TYR A 1 269 ? 27.395 57.877 11.977 1.00 9.07 ? 269 TYR A N 1 ATOM 2031 C CA . TYR A 1 269 ? 28.378 57.156 12.770 1.00 7.41 ? 269 TYR A CA 1 ATOM 2032 C C . TYR A 1 269 ? 28.472 57.635 14.208 1.00 8.44 ? 269 TYR A C 1 ATOM 2033 O O . TYR A 1 269 ? 29.290 57.157 14.952 1.00 8.69 ? 269 TYR A O 1 ATOM 2034 C CB . TYR A 1 269 ? 29.751 57.295 12.105 1.00 7.44 ? 269 TYR A CB 1 ATOM 2035 C CG . TYR A 1 269 ? 30.162 58.731 11.898 1.00 9.58 ? 269 TYR A CG 1 ATOM 2036 C CD1 . TYR A 1 269 ? 30.603 59.508 12.952 1.00 8.56 ? 269 TYR A CD1 1 ATOM 2037 C CD2 . TYR A 1 269 ? 30.099 59.303 10.647 1.00 9.25 ? 269 TYR A CD2 1 ATOM 2038 C CE1 . TYR A 1 269 ? 30.968 60.826 12.776 1.00 9.37 ? 269 TYR A CE1 1 ATOM 2039 C CE2 . TYR A 1 269 ? 30.471 60.633 10.446 1.00 10.30 ? 269 TYR A CE2 1 ATOM 2040 C CZ . TYR A 1 269 ? 30.908 61.376 11.513 1.00 8.55 ? 269 TYR A CZ 1 ATOM 2041 O OH . TYR A 1 269 ? 31.263 62.694 11.277 1.00 10.27 ? 269 TYR A OH 1 ATOM 2042 N N . ASP A 1 270 ? 27.679 58.625 14.587 1.00 7.63 ? 270 ASP A N 1 ATOM 2043 C CA . ASP A 1 270 ? 27.713 59.116 15.980 1.00 8.46 ? 270 ASP A CA 1 ATOM 2044 C C . ASP A 1 270 ? 27.104 58.064 16.948 1.00 7.45 ? 270 ASP A C 1 ATOM 2045 O O . ASP A 1 270 ? 26.517 57.069 16.509 1.00 7.89 ? 270 ASP A O 1 ATOM 2046 C CB . ASP A 1 270 ? 27.071 60.523 16.084 1.00 9.06 ? 270 ASP A CB 1 ATOM 2047 C CG . ASP A 1 270 ? 25.568 60.557 15.876 1.00 12.20 ? 270 ASP A CG 1 ATOM 2048 O OD1 . ASP A 1 270 ? 24.928 59.503 15.717 1.00 12.15 ? 270 ASP A OD1 1 ATOM 2049 O OD2 . ASP A 1 270 ? 25.012 61.721 15.914 1.00 13.57 ? 270 ASP A OD2 1 ATOM 2050 N N . ILE A 1 271 ? 27.314 58.312 18.247 1.00 8.35 ? 271 ILE A N 1 ATOM 2051 C CA . ILE A 1 271 ? 26.881 57.314 19.242 1.00 7.90 ? 271 ILE A CA 1 ATOM 2052 C C . ILE A 1 271 ? 25.373 57.046 19.186 1.00 7.43 ? 271 ILE A C 1 ATOM 2053 O O . ILE A 1 271 ? 24.959 55.891 19.179 1.00 7.88 ? 271 ILE A O 1 ATOM 2054 C CB . ILE A 1 271 ? 27.470 57.646 20.631 1.00 8.71 ? 271 ILE A CB 1 ATOM 2055 C CG1 . ILE A 1 271 ? 29.014 57.489 20.535 1.00 8.09 ? 271 ILE A CG1 1 ATOM 2056 C CG2 . ILE A 1 271 ? 26.885 56.682 21.668 1.00 8.70 ? 271 ILE A CG2 1 ATOM 2057 C CD1 . ILE A 1 271 ? 29.735 58.153 21.697 1.00 8.71 ? 271 ILE A CD1 1 ATOM 2058 N N . PRO A 1 272 ? 24.538 58.091 19.015 1.00 7.97 ? 272 PRO A N 1 ATOM 2059 C CA . PRO A 1 272 ? 23.095 57.834 18.939 1.00 8.41 ? 272 PRO A CA 1 ATOM 2060 C C . PRO A 1 272 ? 22.699 56.922 17.813 1.00 10.01 ? 272 PRO A C 1 ATOM 2061 O O . PRO A 1 272 ? 21.612 56.301 17.888 1.00 10.37 ? 272 PRO A O 1 ATOM 2062 C CB . PRO A 1 272 ? 22.473 59.239 18.766 1.00 8.90 ? 272 PRO A CB 1 ATOM 2063 C CG . PRO A 1 272 ? 23.432 60.160 19.554 1.00 9.64 ? 272 PRO A CG 1 ATOM 2064 C CD . PRO A 1 272 ? 24.818 59.531 19.203 1.00 8.66 ? 272 PRO A CD 1 ATOM 2065 N N . HIS A 1 273 ? 23.521 56.815 16.771 1.00 9.08 ? 273 HIS A N 1 ATOM 2066 C CA . HIS A 1 273 ? 23.175 55.999 15.610 1.00 8.37 ? 273 HIS A CA 1 ATOM 2067 C C . HIS A 1 273 ? 24.085 54.801 15.410 1.00 8.39 ? 273 HIS A C 1 ATOM 2068 O O . HIS A 1 273 ? 24.123 54.243 14.340 1.00 9.73 ? 273 HIS A O 1 ATOM 2069 C CB . HIS A 1 273 ? 23.060 56.853 14.340 1.00 8.29 ? 273 HIS A CB 1 ATOM 2070 C CG . HIS A 1 273 ? 22.004 57.905 14.432 1.00 8.76 ? 273 HIS A CG 1 ATOM 2071 N ND1 . HIS A 1 273 ? 22.260 59.167 14.914 1.00 11.10 ? 273 HIS A ND1 1 ATOM 2072 C CD2 . HIS A 1 273 ? 20.688 57.878 14.117 1.00 7.03 ? 273 HIS A CD2 1 ATOM 2073 C CE1 . HIS A 1 273 ? 21.146 59.877 14.881 1.00 6.33 ? 273 HIS A CE1 1 ATOM 2074 N NE2 . HIS A 1 273 ? 20.179 59.114 14.408 1.00 13.09 ? 273 HIS A NE2 1 ATOM 2075 N N . THR A 1 274 ? 24.776 54.392 16.471 1.00 9.26 ? 274 THR A N 1 ATOM 2076 C CA . THR A 1 274 ? 25.670 53.236 16.333 1.00 8.38 ? 274 THR A CA 1 ATOM 2077 C C . THR A 1 274 ? 25.410 52.150 17.376 1.00 9.06 ? 274 THR A C 1 ATOM 2078 O O . THR A 1 274 ? 25.910 51.051 17.208 1.00 11.49 ? 274 THR A O 1 ATOM 2079 C CB . THR A 1 274 ? 27.167 53.629 16.330 1.00 9.44 ? 274 THR A CB 1 ATOM 2080 O OG1 . THR A 1 274 ? 27.396 54.578 17.368 1.00 9.12 ? 274 THR A OG1 1 ATOM 2081 C CG2 . THR A 1 274 ? 27.547 54.213 14.949 1.00 10.41 ? 274 THR A CG2 1 ATOM 2082 N N . CYS A 1 275 ? 24.642 52.405 18.423 1.00 10.44 ? 275 CYS A N 1 ATOM 2083 C CA . CYS A 1 275 ? 24.357 51.340 19.395 1.00 10.75 ? 275 CYS A CA 1 ATOM 2084 C C . CYS A 1 275 ? 23.226 50.378 19.007 1.00 10.89 ? 275 CYS A C 1 ATOM 2085 O O . CYS A 1 275 ? 23.169 49.263 19.499 1.00 10.85 ? 275 CYS A O 1 ATOM 2086 C CB . CYS A 1 275 ? 24.104 51.928 20.786 1.00 10.82 ? 275 CYS A CB 1 ATOM 2087 S SG . CYS A 1 275 ? 22.360 51.956 21.352 1.00 12.20 ? 275 CYS A SG 1 ATOM 2088 N N . GLY A 1 276 ? 22.341 50.835 18.132 1.00 10.86 ? 276 GLY A N 1 ATOM 2089 C CA . GLY A 1 276 ? 21.097 50.155 17.813 1.00 10.63 ? 276 GLY A CA 1 ATOM 2090 C C . GLY A 1 276 ? 20.182 51.085 17.065 1.00 9.61 ? 276 GLY A C 1 ATOM 2091 O O . GLY A 1 276 ? 20.531 52.246 16.804 1.00 10.33 ? 276 GLY A O 1 ATOM 2092 N N . PRO A 1 277 ? 18.939 50.632 16.775 1.00 9.11 ? 277 PRO A N 1 ATOM 2093 C CA . PRO A 1 277 ? 17.971 51.410 16.005 1.00 10.35 ? 277 PRO A CA 1 ATOM 2094 C C . PRO A 1 277 ? 17.312 52.606 16.615 1.00 9.69 ? 277 PRO A C 1 ATOM 2095 O O . PRO A 1 277 ? 16.736 53.406 15.873 1.00 10.14 ? 277 PRO A O 1 ATOM 2096 C CB . PRO A 1 277 ? 16.897 50.354 15.596 1.00 10.89 ? 277 PRO A CB 1 ATOM 2097 C CG . PRO A 1 277 ? 16.969 49.392 16.842 1.00 10.11 ? 277 PRO A CG 1 ATOM 2098 C CD . PRO A 1 277 ? 18.439 49.286 17.126 1.00 9.48 ? 277 PRO A CD 1 ATOM 2099 N N . ASP A 1 278 ? 17.349 52.745 17.923 1.00 9.63 ? 278 ASP A N 1 ATOM 2100 C CA . ASP A 1 278 ? 16.639 53.859 18.553 1.00 9.26 ? 278 ASP A CA 1 ATOM 2101 C C . ASP A 1 278 ? 17.598 54.900 19.099 1.00 10.34 ? 278 ASP A C 1 ATOM 2102 O O . ASP A 1 278 ? 18.176 54.721 20.167 1.00 9.83 ? 278 ASP A O 1 ATOM 2103 C CB . ASP A 1 278 ? 15.787 53.326 19.735 1.00 10.92 ? 278 ASP A CB 1 ATOM 2104 C CG . ASP A 1 278 ? 14.874 54.411 20.282 1.00 10.41 ? 278 ASP A CG 1 ATOM 2105 O OD1 . ASP A 1 278 ? 15.017 55.609 19.963 1.00 12.74 ? 278 ASP A OD1 1 ATOM 2106 O OD2 . ASP A 1 278 ? 13.957 54.049 21.077 1.00 15.24 ? 278 ASP A OD2 1 ATOM 2107 N N . PRO A 1 279 ? 17.740 56.043 18.404 1.00 10.09 ? 279 PRO A N 1 ATOM 2108 C CA . PRO A 1 279 ? 18.677 57.060 18.910 1.00 10.26 ? 279 PRO A CA 1 ATOM 2109 C C . PRO A 1 279 ? 18.374 57.652 20.249 1.00 9.64 ? 279 PRO A C 1 ATOM 2110 O O . PRO A 1 279 ? 19.261 58.109 20.940 1.00 10.90 ? 279 PRO A O 1 ATOM 2111 C CB . PRO A 1 279 ? 18.747 58.076 17.758 1.00 10.96 ? 279 PRO A CB 1 ATOM 2112 C CG . PRO A 1 279 ? 17.360 57.968 17.148 1.00 10.75 ? 279 PRO A CG 1 ATOM 2113 C CD . PRO A 1 279 ? 17.010 56.475 17.196 1.00 11.23 ? 279 PRO A CD 1 ATOM 2114 N N . LYS A 1 280 ? 17.081 57.659 20.639 1.00 9.71 ? 280 LYS A N 1 ATOM 2115 C CA . LYS A 1 280 ? 16.716 58.236 21.928 1.00 10.03 ? 280 LYS A CA 1 ATOM 2116 C C . LYS A 1 280 ? 17.324 57.345 23.029 1.00 9.98 ? 280 LYS A C 1 ATOM 2117 O O . LYS A 1 280 ? 17.670 57.858 24.103 1.00 12.22 ? 280 LYS A O 1 ATOM 2118 C CB . LYS A 1 280 ? 15.190 58.318 22.072 1.00 13.31 ? 280 LYS A CB 1 ATOM 2119 C CG . LYS A 1 280 ? 14.741 58.785 23.438 1.00 15.69 ? 280 LYS A CG 1 ATOM 2120 C CD . LYS A 1 280 ? 13.199 58.768 23.454 1.00 24.50 ? 280 LYS A CD 1 ATOM 2121 C CE . LYS A 1 280 ? 12.756 57.962 24.681 1.00 35.12 ? 280 LYS A CE 1 ATOM 2122 N NZ . LYS A 1 280 ? 13.620 56.711 24.916 1.00 39.00 ? 280 LYS A NZ 1 ATOM 2123 N N . VAL A 1 281 ? 17.453 56.046 22.763 1.00 10.80 ? 281 VAL A N 1 ATOM 2124 C CA . VAL A 1 281 ? 18.089 55.176 23.732 1.00 10.75 ? 281 VAL A CA 1 ATOM 2125 C C . VAL A 1 281 ? 19.632 55.284 23.636 1.00 9.71 ? 281 VAL A C 1 ATOM 2126 O O . VAL A 1 281 ? 20.334 55.458 24.649 1.00 10.27 ? 281 VAL A O 1 ATOM 2127 C CB . VAL A 1 281 ? 17.642 53.674 23.532 1.00 11.65 ? 281 VAL A CB 1 ATOM 2128 C CG1 . VAL A 1 281 ? 18.426 52.752 24.494 1.00 13.14 ? 281 VAL A CG1 1 ATOM 2129 C CG2 . VAL A 1 281 ? 16.113 53.539 23.789 1.00 12.57 ? 281 VAL A CG2 1 ATOM 2130 N N . CYS A 1 282 ? 20.165 55.110 22.402 1.00 9.22 ? 282 CYS A N 1 ATOM 2131 C CA . CYS A 1 282 ? 21.608 55.119 22.238 1.00 10.07 ? 282 CYS A CA 1 ATOM 2132 C C . CYS A 1 282 ? 22.257 56.413 22.731 1.00 8.02 ? 282 CYS A C 1 ATOM 2133 O O . CYS A 1 282 ? 23.366 56.394 23.245 1.00 9.29 ? 282 CYS A O 1 ATOM 2134 C CB . CYS A 1 282 ? 21.977 54.913 20.761 1.00 10.10 ? 282 CYS A CB 1 ATOM 2135 S SG . CYS A 1 282 ? 21.524 53.323 20.075 1.00 11.78 ? 282 CYS A SG 1 ATOM 2136 N N . CYS A 1 283 ? 21.567 57.564 22.579 1.00 8.71 ? 283 CYS A N 1 ATOM 2137 C CA . CYS A 1 283 ? 22.125 58.789 23.064 1.00 9.53 ? 283 CYS A CA 1 ATOM 2138 C C . CYS A 1 283 ? 22.437 58.791 24.563 1.00 8.94 ? 283 CYS A C 1 ATOM 2139 O O . CYS A 1 283 ? 23.348 59.451 25.026 1.00 9.09 ? 283 CYS A O 1 ATOM 2140 C CB . CYS A 1 283 ? 21.183 59.950 22.682 1.00 10.49 ? 283 CYS A CB 1 ATOM 2141 S SG . CYS A 1 283 ? 21.987 61.580 22.797 1.00 12.02 ? 283 CYS A SG 1 ATOM 2142 N N . GLN A 1 284 ? 21.677 57.962 25.320 1.00 9.98 ? 284 GLN A N 1 ATOM 2143 C CA . GLN A 1 284 ? 21.889 57.861 26.746 1.00 10.61 ? 284 GLN A CA 1 ATOM 2144 C C . GLN A 1 284 ? 23.149 57.082 27.091 1.00 8.59 ? 284 GLN A C 1 ATOM 2145 O O . GLN A 1 284 ? 23.516 57.008 28.257 1.00 11.21 ? 284 GLN A O 1 ATOM 2146 C CB . GLN A 1 284 ? 20.687 57.186 27.404 1.00 11.12 ? 284 GLN A CB 1 ATOM 2147 C CG . GLN A 1 284 ? 19.398 57.950 27.197 1.00 11.20 ? 284 GLN A CG 1 ATOM 2148 C CD . GLN A 1 284 ? 18.205 57.151 27.719 1.00 15.03 ? 284 GLN A CD 1 ATOM 2149 O OE1 . GLN A 1 284 ? 18.182 56.773 28.886 1.00 16.22 ? 284 GLN A OE1 1 ATOM 2150 N NE2 . GLN A 1 284 ? 17.227 56.913 26.867 1.00 15.08 ? 284 GLN A NE2 1 ATOM 2151 N N . PHE A 1 285 ? 23.846 56.548 26.076 1.00 8.68 ? 285 PHE A N 1 ATOM 2152 C CA . PHE A 1 285 ? 25.082 55.826 26.286 1.00 8.83 ? 285 PHE A CA 1 ATOM 2153 C C . PHE A 1 285 ? 26.271 56.566 25.668 1.00 8.19 ? 285 PHE A C 1 ATOM 2154 O O . PHE A 1 285 ? 27.327 55.965 25.430 1.00 9.43 ? 285 PHE A O 1 ATOM 2155 C CB . PHE A 1 285 ? 24.916 54.367 25.817 1.00 8.79 ? 285 PHE A CB 1 ATOM 2156 C CG . PHE A 1 285 ? 23.896 53.628 26.672 1.00 9.74 ? 285 PHE A CG 1 ATOM 2157 C CD1 . PHE A 1 285 ? 24.286 53.031 27.872 1.00 10.68 ? 285 PHE A CD1 1 ATOM 2158 C CD2 . PHE A 1 285 ? 22.543 53.621 26.296 1.00 11.06 ? 285 PHE A CD2 1 ATOM 2159 C CE1 . PHE A 1 285 ? 23.318 52.424 28.696 1.00 11.44 ? 285 PHE A CE1 1 ATOM 2160 C CE2 . PHE A 1 285 ? 21.566 53.021 27.122 1.00 12.73 ? 285 PHE A CE2 1 ATOM 2161 C CZ . PHE A 1 285 ? 21.980 52.418 28.334 1.00 12.19 ? 285 PHE A CZ 1 ATOM 2162 N N . ASP A 1 286 ? 26.066 57.862 25.417 1.00 8.87 ? 286 ASP A N 1 ATOM 2163 C CA . ASP A 1 286 ? 27.162 58.749 25.019 1.00 8.03 ? 286 ASP A CA 1 ATOM 2164 C C . ASP A 1 286 ? 27.408 59.556 26.305 1.00 9.02 ? 286 ASP A C 1 ATOM 2165 O O . ASP A 1 286 ? 26.724 60.563 26.532 1.00 9.50 ? 286 ASP A O 1 ATOM 2166 C CB . ASP A 1 286 ? 26.763 59.638 23.865 1.00 9.24 ? 286 ASP A CB 1 ATOM 2167 C CG . ASP A 1 286 ? 27.927 60.512 23.400 1.00 7.62 ? 286 ASP A CG 1 ATOM 2168 O OD1 . ASP A 1 286 ? 28.938 60.590 24.123 1.00 8.33 ? 286 ASP A OD1 1 ATOM 2169 O OD2 . ASP A 1 286 ? 27.738 61.141 22.346 1.00 8.76 ? 286 ASP A OD2 1 ATOM 2170 N N . PHE A 1 287 ? 28.383 59.153 27.121 1.00 7.49 ? 287 PHE A N 1 ATOM 2171 C CA . PHE A 1 287 ? 28.523 59.755 28.420 1.00 7.97 ? 287 PHE A CA 1 ATOM 2172 C C . PHE A 1 287 ? 29.102 61.129 28.423 1.00 10.35 ? 287 PHE A C 1 ATOM 2173 O O . PHE A 1 287 ? 29.199 61.750 29.473 1.00 10.97 ? 287 PHE A O 1 ATOM 2174 C CB . PHE A 1 287 ? 29.232 58.774 29.373 1.00 9.80 ? 287 PHE A CB 1 ATOM 2175 C CG . PHE A 1 287 ? 28.425 57.514 29.624 1.00 9.29 ? 287 PHE A CG 1 ATOM 2176 C CD1 . PHE A 1 287 ? 27.428 57.514 30.646 1.00 10.10 ? 287 PHE A CD1 1 ATOM 2177 C CD2 . PHE A 1 287 ? 28.586 56.388 28.841 1.00 9.84 ? 287 PHE A CD2 1 ATOM 2178 C CE1 . PHE A 1 287 ? 26.624 56.387 30.854 1.00 9.24 ? 287 PHE A CE1 1 ATOM 2179 C CE2 . PHE A 1 287 ? 27.779 55.275 29.017 1.00 10.89 ? 287 PHE A CE2 1 ATOM 2180 C CZ . PHE A 1 287 ? 26.772 55.258 30.056 1.00 10.19 ? 287 PHE A CZ 1 ATOM 2181 N N . LYS A 1 288 ? 29.466 61.648 27.238 1.00 9.59 ? 288 LYS A N 1 ATOM 2182 C CA . LYS A 1 288 ? 29.906 63.031 27.141 1.00 9.32 ? 288 LYS A CA 1 ATOM 2183 C C . LYS A 1 288 ? 28.695 63.983 27.077 1.00 10.49 ? 288 LYS A C 1 ATOM 2184 O O . LYS A 1 288 ? 28.902 65.197 27.104 1.00 10.92 ? 288 LYS A O 1 ATOM 2185 C CB . LYS A 1 288 ? 30.749 63.214 25.828 1.00 9.73 ? 288 LYS A CB 1 ATOM 2186 C CG . LYS A 1 288 ? 31.627 64.521 25.918 1.00 9.58 ? 288 LYS A CG 1 ATOM 2187 C CD . LYS A 1 288 ? 32.490 64.649 24.667 1.00 8.93 ? 288 LYS A CD 1 ATOM 2188 C CE . LYS A 1 288 ? 33.311 65.916 24.828 1.00 9.52 ? 288 LYS A CE 1 ATOM 2189 N NZ . LYS A 1 288 ? 34.326 66.065 23.656 1.00 12.01 ? 288 LYS A NZ 1 ATOM 2190 N N . ARG A 1 289 ? 27.443 63.485 27.068 1.00 10.19 ? 289 ARG A N 1 ATOM 2191 C CA . ARG A 1 289 ? 26.294 64.367 26.909 1.00 10.70 ? 289 ARG A CA 1 ATOM 2192 C C . ARG A 1 289 ? 25.483 64.656 28.216 1.00 13.16 ? 289 ARG A C 1 ATOM 2193 O O . ARG A 1 289 ? 24.267 64.920 28.129 1.00 14.46 ? 289 ARG A O 1 ATOM 2194 C CB . ARG A 1 289 ? 25.326 63.788 25.879 1.00 10.17 ? 289 ARG A CB 1 ATOM 2195 C CG . ARG A 1 289 ? 25.960 63.588 24.507 1.00 10.86 ? 289 ARG A CG 1 ATOM 2196 C CD . ARG A 1 289 ? 24.963 63.151 23.520 1.00 11.92 ? 289 ARG A CD 1 ATOM 2197 N NE . ARG A 1 289 ? 25.515 62.868 22.190 1.00 10.85 ? 289 ARG A NE 1 ATOM 2198 C CZ . ARG A 1 289 ? 25.075 63.390 21.057 1.00 9.95 ? 289 ARG A CZ 1 ATOM 2199 N NH1 . ARG A 1 289 ? 24.074 64.287 21.032 1.00 12.75 ? 289 ARG A NH1 1 ATOM 2200 N NH2 . ARG A 1 289 ? 25.573 62.910 19.903 1.00 10.99 ? 289 ARG A NH2 1 ATOM 2201 N N . MET A 1 290 ? 26.137 64.666 29.387 1.00 17.11 ? 290 MET A N 1 ATOM 2202 C CA . MET A 1 290 ? 25.404 64.897 30.661 1.00 18.53 ? 290 MET A CA 1 ATOM 2203 C C . MET A 1 290 ? 25.329 66.377 31.069 1.00 20.95 ? 290 MET A C 1 ATOM 2204 O O . MET A 1 290 ? 24.562 66.720 32.017 1.00 22.25 ? 290 MET A O 1 ATOM 2205 C CB . MET A 1 290 ? 25.962 64.003 31.795 1.00 19.33 ? 290 MET A CB 1 ATOM 2206 C CG . MET A 1 290 ? 25.758 62.551 31.479 1.00 20.76 ? 290 MET A CG 1 ATOM 2207 S SD . MET A 1 290 ? 26.182 61.426 32.816 1.00 21.64 ? 290 MET A SD 1 ATOM 2208 C CE . MET A 1 290 ? 27.963 61.510 32.717 1.00 21.57 ? 290 MET A CE 1 ATOM 2209 N N . GLY A 1 291 ? 26.081 67.248 30.351 1.00 18.51 ? 291 GLY A N 1 ATOM 2210 C CA . GLY A 1 291 ? 26.021 68.692 30.601 1.00 17.87 ? 291 GLY A CA 1 ATOM 2211 C C . GLY A 1 291 ? 27.324 69.521 30.693 1.00 20.67 ? 291 GLY A C 1 ATOM 2212 O O . GLY A 1 291 ? 27.490 70.582 30.030 1.00 20.15 ? 291 GLY A O 1 ATOM 2213 N N . SER A 1 292 ? 28.270 69.046 31.503 1.00 17.54 ? 292 SER A N 1 ATOM 2214 C CA . SER A 1 292 ? 29.515 69.775 31.707 1.00 13.00 ? 292 SER A CA 1 ATOM 2215 C C . SER A 1 292 ? 30.406 69.960 30.470 1.00 12.39 ? 292 SER A C 1 ATOM 2216 O O . SER A 1 292 ? 31.318 70.796 30.505 1.00 12.32 ? 292 SER A O 1 ATOM 2217 C CB . SER A 1 292 ? 30.308 69.109 32.822 1.00 15.62 ? 292 SER A CB 1 ATOM 2218 O OG . SER A 1 292 ? 30.804 67.867 32.333 1.00 17.98 ? 292 SER A OG 1 ATOM 2219 N N . PHE A 1 293 ? 30.183 69.151 29.424 1.00 10.96 ? 293 PHE A N 1 ATOM 2220 C CA . PHE A 1 293 ? 30.900 69.255 28.163 1.00 10.31 ? 293 PHE A CA 1 ATOM 2221 C C . PHE A 1 293 ? 30.139 70.068 27.129 1.00 11.60 ? 293 PHE A C 1 ATOM 2222 O O . PHE A 1 293 ? 30.586 70.144 25.983 1.00 13.58 ? 293 PHE A O 1 ATOM 2223 C CB . PHE A 1 293 ? 31.175 67.814 27.578 1.00 12.87 ? 293 PHE A CB 1 ATOM 2224 C CG . PHE A 1 293 ? 32.092 66.991 28.418 1.00 11.65 ? 293 PHE A CG 1 ATOM 2225 C CD1 . PHE A 1 293 ? 33.442 67.123 28.290 1.00 11.61 ? 293 PHE A CD1 1 ATOM 2226 C CD2 . PHE A 1 293 ? 31.577 66.061 29.291 1.00 11.96 ? 293 PHE A CD2 1 ATOM 2227 C CE1 . PHE A 1 293 ? 34.332 66.291 29.048 1.00 14.16 ? 293 PHE A CE1 1 ATOM 2228 C CE2 . PHE A 1 293 ? 32.429 65.230 30.062 1.00 12.52 ? 293 PHE A CE2 1 ATOM 2229 C CZ . PHE A 1 293 ? 33.800 65.371 29.914 1.00 13.92 ? 293 PHE A CZ 1 ATOM 2230 N N . GLY A 1 294 ? 29.008 70.654 27.528 1.00 12.71 ? 294 GLY A N 1 ATOM 2231 C CA . GLY A 1 294 ? 28.258 71.451 26.544 1.00 13.53 ? 294 GLY A CA 1 ATOM 2232 C C . GLY A 1 294 ? 27.532 70.671 25.452 1.00 14.33 ? 294 GLY A C 1 ATOM 2233 O O . GLY A 1 294 ? 27.231 71.188 24.365 1.00 17.20 ? 294 GLY A O 1 ATOM 2234 N N . LEU A 1 295 ? 27.276 69.388 25.693 1.00 12.56 ? 295 LEU A N 1 ATOM 2235 C CA . LEU A 1 295 ? 26.561 68.560 24.745 1.00 11.38 ? 295 LEU A CA 1 ATOM 2236 C C . LEU A 1 295 ? 25.320 68.001 25.452 1.00 13.19 ? 295 LEU A C 1 ATOM 2237 O O . LEU A 1 295 ? 25.321 67.864 26.668 1.00 14.43 ? 295 LEU A O 1 ATOM 2238 C CB . LEU A 1 295 ? 27.432 67.390 24.270 1.00 12.54 ? 295 LEU A CB 1 ATOM 2239 C CG . LEU A 1 295 ? 28.773 67.842 23.671 1.00 13.80 ? 295 LEU A CG 1 ATOM 2240 C CD1 . LEU A 1 295 ? 29.615 66.599 23.374 1.00 14.54 ? 295 LEU A CD1 1 ATOM 2241 C CD2 . LEU A 1 295 ? 28.523 68.622 22.350 1.00 15.60 ? 295 LEU A CD2 1 ATOM 2242 N N . SER A 1 296 ? 24.304 67.663 24.668 1.00 11.40 ? 296 SER A N 1 ATOM 2243 C CA . SER A 1 296 ? 23.057 67.127 25.216 1.00 13.78 ? 296 SER A CA 1 ATOM 2244 C C . SER A 1 296 ? 22.460 66.201 24.180 1.00 13.70 ? 296 SER A C 1 ATOM 2245 O O . SER A 1 296 ? 22.981 66.047 23.074 1.00 12.90 ? 296 SER A O 1 ATOM 2246 C CB . SER A 1 296 ? 22.080 68.302 25.579 1.00 14.91 ? 296 SER A CB 1 ATOM 2247 O OG . SER A 1 296 ? 21.828 69.089 24.435 1.00 17.19 ? 296 SER A OG 1 ATOM 2248 N N . CYS A 1 297 ? 21.348 65.529 24.556 1.00 13.35 ? 297 CYS A N 1 ATOM 2249 C CA . CYS A 1 297 ? 20.628 64.612 23.656 1.00 13.81 ? 297 CYS A CA 1 ATOM 2250 C C . CYS A 1 297 ? 19.412 65.320 23.071 1.00 13.63 ? 297 CYS A C 1 ATOM 2251 O O . CYS A 1 297 ? 18.522 65.733 23.858 1.00 15.63 ? 297 CYS A O 1 ATOM 2252 C CB . CYS A 1 297 ? 20.153 63.366 24.429 1.00 14.08 ? 297 CYS A CB 1 ATOM 2253 S SG . CYS A 1 297 ? 21.574 62.228 24.737 1.00 15.65 ? 297 CYS A SG 1 ATOM 2254 N N . PRO A 1 298 ? 19.315 65.419 21.748 1.00 15.85 ? 298 PRO A N 1 ATOM 2255 C CA . PRO A 1 298 ? 18.135 66.115 21.213 1.00 17.10 ? 298 PRO A CA 1 ATOM 2256 C C . PRO A 1 298 ? 16.842 65.346 21.410 1.00 14.91 ? 298 PRO A C 1 ATOM 2257 O O . PRO A 1 298 ? 15.751 65.924 21.240 1.00 16.74 ? 298 PRO A O 1 ATOM 2258 C CB . PRO A 1 298 ? 18.460 66.365 19.752 1.00 20.69 ? 298 PRO A CB 1 ATOM 2259 C CG . PRO A 1 298 ? 19.665 65.510 19.417 1.00 18.83 ? 298 PRO A CG 1 ATOM 2260 C CD . PRO A 1 298 ? 20.366 65.170 20.732 1.00 13.32 ? 298 PRO A CD 1 ATOM 2261 N N . TRP A 1 299 ? 16.904 64.061 21.743 1.00 12.32 ? 299 TRP A N 1 ATOM 2262 C CA . TRP A 1 299 ? 15.692 63.263 21.989 1.00 13.91 ? 299 TRP A CA 1 ATOM 2263 C C . TRP A 1 299 ? 15.217 63.478 23.425 1.00 14.51 ? 299 TRP A C 1 ATOM 2264 O O . TRP A 1 299 ? 14.245 62.883 23.865 1.00 16.89 ? 299 TRP A O 1 ATOM 2265 C CB . TRP A 1 299 ? 15.962 61.761 21.694 1.00 13.00 ? 299 TRP A CB 1 ATOM 2266 C CG . TRP A 1 299 ? 16.339 61.581 20.255 1.00 12.18 ? 299 TRP A CG 1 ATOM 2267 C CD1 . TRP A 1 299 ? 15.498 61.395 19.211 1.00 12.75 ? 299 TRP A CD1 1 ATOM 2268 C CD2 . TRP A 1 299 ? 17.654 61.649 19.704 1.00 10.15 ? 299 TRP A CD2 1 ATOM 2269 N NE1 . TRP A 1 299 ? 16.206 61.309 18.042 1.00 15.17 ? 299 TRP A NE1 1 ATOM 2270 C CE2 . TRP A 1 299 ? 17.532 61.470 18.323 1.00 12.78 ? 299 TRP A CE2 1 ATOM 2271 C CE3 . TRP A 1 299 ? 18.924 61.811 20.253 1.00 12.71 ? 299 TRP A CE3 1 ATOM 2272 C CZ2 . TRP A 1 299 ? 18.622 61.470 17.477 1.00 13.72 ? 299 TRP A CZ2 1 ATOM 2273 C CZ3 . TRP A 1 299 ? 20.005 61.809 19.411 1.00 12.76 ? 299 TRP A CZ3 1 ATOM 2274 C CH2 . TRP A 1 299 ? 19.845 61.648 18.038 1.00 12.15 ? 299 TRP A CH2 1 ATOM 2275 N N . LYS A 1 300 ? 15.914 64.356 24.134 1.00 13.14 ? 300 LYS A N 1 ATOM 2276 C CA . LYS A 1 300 ? 15.496 64.837 25.469 1.00 15.29 ? 300 LYS A CA 1 ATOM 2277 C C . LYS A 1 300 ? 15.598 63.896 26.651 1.00 19.05 ? 300 LYS A C 1 ATOM 2278 O O . LYS A 1 300 ? 14.974 64.142 27.701 1.00 20.06 ? 300 LYS A O 1 ATOM 2279 C CB . LYS A 1 300 ? 14.057 65.391 25.366 1.00 19.22 ? 300 LYS A CB 1 ATOM 2280 C CG . LYS A 1 300 ? 13.891 66.517 24.400 1.00 23.96 ? 300 LYS A CG 1 ATOM 2281 C CD . LYS A 1 300 ? 12.401 66.831 24.303 1.00 26.23 ? 300 LYS A CD 1 ATOM 2282 C CE . LYS A 1 300 ? 12.144 67.988 23.378 1.00 33.03 ? 300 LYS A CE 1 ATOM 2283 N NZ . LYS A 1 300 ? 12.786 67.759 22.060 1.00 38.40 ? 300 LYS A NZ 1 ATOM 2284 N N . VAL A 1 301 ? 16.319 62.789 26.508 1.00 15.02 ? 301 VAL A N 1 ATOM 2285 C CA . VAL A 1 301 ? 16.558 61.907 27.621 1.00 15.59 ? 301 VAL A CA 1 ATOM 2286 C C . VAL A 1 301 ? 18.100 61.899 27.730 1.00 14.44 ? 301 VAL A C 1 ATOM 2287 O O . VAL A 1 301 ? 18.782 61.458 26.808 1.00 16.12 ? 301 VAL A O 1 ATOM 2288 C CB . VAL A 1 301 ? 16.025 60.499 27.388 1.00 17.04 ? 301 VAL A CB 1 ATOM 2289 C CG1 . VAL A 1 301 ? 16.266 59.715 28.681 1.00 19.29 ? 301 VAL A CG1 1 ATOM 2290 C CG2 . VAL A 1 301 ? 14.458 60.531 27.049 1.00 20.03 ? 301 VAL A CG2 1 ATOM 2291 N N . PRO A 1 302 ? 18.657 62.349 28.841 1.00 14.57 ? 302 PRO A N 1 ATOM 2292 C CA . PRO A 1 302 ? 20.110 62.382 28.954 1.00 15.15 ? 302 PRO A CA 1 ATOM 2293 C C . PRO A 1 302 ? 20.737 61.111 29.446 1.00 14.33 ? 302 PRO A C 1 ATOM 2294 O O . PRO A 1 302 ? 20.072 60.194 29.928 1.00 14.55 ? 302 PRO A O 1 ATOM 2295 C CB . PRO A 1 302 ? 20.339 63.473 30.004 1.00 15.35 ? 302 PRO A CB 1 ATOM 2296 C CG . PRO A 1 302 ? 19.140 63.207 30.988 1.00 17.82 ? 302 PRO A CG 1 ATOM 2297 C CD . PRO A 1 302 ? 17.996 62.926 30.043 1.00 16.43 ? 302 PRO A CD 1 ATOM 2298 N N . PRO A 1 303 ? 22.045 60.969 29.231 1.00 11.82 ? 303 PRO A N 1 ATOM 2299 C CA . PRO A 1 303 ? 22.709 59.798 29.780 1.00 11.87 ? 303 PRO A CA 1 ATOM 2300 C C . PRO A 1 303 ? 22.735 60.012 31.314 1.00 14.87 ? 303 PRO A C 1 ATOM 2301 O O . PRO A 1 303 ? 22.659 61.150 31.828 1.00 14.07 ? 303 PRO A O 1 ATOM 2302 C CB . PRO A 1 303 ? 24.168 59.933 29.331 1.00 12.50 ? 303 PRO A CB 1 ATOM 2303 C CG . PRO A 1 303 ? 24.241 61.209 28.525 1.00 15.96 ? 303 PRO A CG 1 ATOM 2304 C CD . PRO A 1 303 ? 22.953 61.899 28.534 1.00 14.20 ? 303 PRO A CD 1 ATOM 2305 N N . ARG A 1 304 ? 22.810 58.906 32.044 1.00 14.72 ? 304 ARG A N 1 ATOM 2306 C CA . ARG A 1 304 ? 22.959 58.971 33.483 1.00 16.15 ? 304 ARG A CA 1 ATOM 2307 C C . ARG A 1 304 ? 24.140 58.100 33.850 1.00 11.40 ? 304 ARG A C 1 ATOM 2308 O O . ARG A 1 304 ? 24.345 57.019 33.253 1.00 12.65 ? 304 ARG A O 1 ATOM 2309 C CB . ARG A 1 304 ? 21.710 58.459 34.200 1.00 19.21 ? 304 ARG A CB 1 ATOM 2310 C CG . ARG A 1 304 ? 20.625 59.508 34.284 1.00 24.58 ? 304 ARG A CG 1 ATOM 2311 C CD . ARG A 1 304 ? 19.412 58.946 34.979 1.00 28.06 ? 304 ARG A CD 1 ATOM 2312 N NE . ARG A 1 304 ? 18.639 58.086 34.087 1.00 30.08 ? 304 ARG A NE 1 ATOM 2313 C CZ . ARG A 1 304 ? 18.436 56.790 34.297 1.00 34.99 ? 304 ARG A CZ 1 ATOM 2314 N NH1 . ARG A 1 304 ? 18.958 56.199 35.372 1.00 37.80 ? 304 ARG A NH1 1 ATOM 2315 N NH2 . ARG A 1 304 ? 17.696 56.093 33.448 1.00 37.25 ? 304 ARG A NH2 1 ATOM 2316 N N . THR A 1 305 ? 24.923 58.568 34.808 1.00 12.67 ? 305 THR A N 1 ATOM 2317 C CA . THR A 1 305 ? 26.085 57.826 35.302 1.00 13.04 ? 305 THR A CA 1 ATOM 2318 C C . THR A 1 305 ? 25.673 56.438 35.734 1.00 13.03 ? 305 THR A C 1 ATOM 2319 O O . THR A 1 305 ? 24.633 56.300 36.396 1.00 13.52 ? 305 THR A O 1 ATOM 2320 C CB . THR A 1 305 ? 26.743 58.562 36.487 1.00 15.80 ? 305 THR A CB 1 ATOM 2321 O OG1 . THR A 1 305 ? 27.268 59.805 35.975 1.00 16.18 ? 305 THR A OG1 1 ATOM 2322 C CG2 . THR A 1 305 ? 27.819 57.768 37.157 1.00 16.50 ? 305 THR A CG2 1 ATOM 2323 N N . ILE A 1 306 ? 26.422 55.405 35.363 1.00 10.70 ? 306 ILE A N 1 ATOM 2324 C CA . ILE A 1 306 ? 26.080 54.025 35.728 1.00 10.00 ? 306 ILE A CA 1 ATOM 2325 C C . ILE A 1 306 ? 26.470 53.804 37.175 1.00 10.86 ? 306 ILE A C 1 ATOM 2326 O O . ILE A 1 306 ? 27.539 54.178 37.619 1.00 12.96 ? 306 ILE A O 1 ATOM 2327 C CB . ILE A 1 306 ? 26.798 53.029 34.758 1.00 9.13 ? 306 ILE A CB 1 ATOM 2328 C CG1 . ILE A 1 306 ? 26.448 53.343 33.286 1.00 10.55 ? 306 ILE A CG1 1 ATOM 2329 C CG2 . ILE A 1 306 ? 26.386 51.548 35.116 1.00 11.00 ? 306 ILE A CG2 1 ATOM 2330 C CD1 . ILE A 1 306 ? 24.947 53.301 32.940 1.00 11.43 ? 306 ILE A CD1 1 ATOM 2331 N N . SER A 1 307 ? 25.527 53.200 37.920 1.00 12.11 ? 307 SER A N 1 ATOM 2332 C CA . SER A 1 307 ? 25.733 52.892 39.354 1.00 12.54 ? 307 SER A CA 1 ATOM 2333 C C . SER A 1 307 ? 25.254 51.464 39.608 1.00 11.43 ? 307 SER A C 1 ATOM 2334 O O . SER A 1 307 ? 24.556 50.867 38.784 1.00 11.07 ? 307 SER A O 1 ATOM 2335 C CB . SER A 1 307 ? 24.863 53.821 40.217 1.00 12.67 ? 307 SER A CB 1 ATOM 2336 O OG . SER A 1 307 ? 23.493 53.492 40.032 1.00 13.53 ? 307 SER A OG 1 ATOM 2337 N N . ASP A 1 308 ? 25.562 50.929 40.802 1.00 13.42 ? 308 ASP A N 1 ATOM 2338 C CA . ASP A 1 308 ? 25.028 49.599 41.060 1.00 13.95 ? 308 ASP A CA 1 ATOM 2339 C C . ASP A 1 308 ? 23.486 49.579 41.125 1.00 12.49 ? 308 ASP A C 1 ATOM 2340 O O . ASP A 1 308 ? 22.905 48.507 40.886 1.00 13.28 ? 308 ASP A O 1 ATOM 2341 C CB . ASP A 1 308 ? 25.554 49.035 42.377 1.00 19.28 ? 308 ASP A CB 1 ATOM 2342 C CG . ASP A 1 308 ? 27.063 48.866 42.394 1.00 24.36 ? 308 ASP A CG 1 ATOM 2343 O OD1 . ASP A 1 308 ? 27.710 48.751 41.320 1.00 25.87 ? 308 ASP A OD1 1 ATOM 2344 O OD2 . ASP A 1 308 ? 27.608 48.825 43.522 1.00 30.14 ? 308 ASP A OD2 1 ATOM 2345 N N . GLN A 1 309 ? 22.844 50.723 41.364 1.00 12.83 ? 309 GLN A N 1 ATOM 2346 C CA . GLN A 1 309 ? 21.376 50.770 41.463 1.00 13.22 ? 309 GLN A CA 1 ATOM 2347 C C . GLN A 1 309 ? 20.681 50.874 40.122 1.00 14.20 ? 309 GLN A C 1 ATOM 2348 O O . GLN A 1 309 ? 19.519 50.508 40.007 1.00 15.10 ? 309 GLN A O 1 ATOM 2349 C CB . GLN A 1 309 ? 20.934 51.934 42.363 1.00 11.47 ? 309 GLN A CB 1 ATOM 2350 C CG . GLN A 1 309 ? 21.365 51.811 43.819 1.00 14.86 ? 309 GLN A CG 1 ATOM 2351 C CD . GLN A 1 309 ? 22.869 51.958 44.005 1.00 16.57 ? 309 GLN A CD 1 ATOM 2352 O OE1 . GLN A 1 309 ? 23.478 52.902 43.477 1.00 17.82 ? 309 GLN A OE1 1 ATOM 2353 N NE2 . GLN A 1 309 ? 23.476 51.036 44.755 1.00 18.70 ? 309 GLN A NE2 1 ATOM 2354 N N . ASN A 1 310 ? 21.371 51.369 39.089 1.00 12.70 ? 310 ASN A N 1 ATOM 2355 C CA . ASN A 1 310 ? 20.732 51.477 37.785 1.00 10.67 ? 310 ASN A CA 1 ATOM 2356 C C . ASN A 1 310 ? 21.384 50.605 36.719 1.00 10.08 ? 310 ASN A C 1 ATOM 2357 O O . ASN A 1 310 ? 20.858 50.530 35.631 1.00 11.12 ? 310 ASN A O 1 ATOM 2358 C CB . ASN A 1 310 ? 20.655 52.956 37.307 1.00 12.19 ? 310 ASN A CB 1 ATOM 2359 C CG . ASN A 1 310 ? 22.029 53.527 36.925 1.00 12.76 ? 310 ASN A CG 1 ATOM 2360 O OD1 . ASN A 1 310 ? 22.975 52.782 36.674 1.00 12.03 ? 310 ASN A OD1 1 ATOM 2361 N ND2 . ASN A 1 310 ? 22.114 54.852 36.855 1.00 14.44 ? 310 ASN A ND2 1 ATOM 2362 N N . VAL A 1 311 ? 22.439 49.880 37.045 1.00 10.19 ? 311 VAL A N 1 ATOM 2363 C CA . VAL A 1 311 ? 23.145 49.145 36.001 1.00 10.76 ? 311 VAL A CA 1 ATOM 2364 C C . VAL A 1 311 ? 22.285 48.070 35.354 1.00 10.63 ? 311 VAL A C 1 ATOM 2365 O O . VAL A 1 311 ? 22.378 47.877 34.166 1.00 10.98 ? 311 VAL A O 1 ATOM 2366 C CB . VAL A 1 311 ? 24.507 48.602 36.441 1.00 10.27 ? 311 VAL A CB 1 ATOM 2367 C CG1 . VAL A 1 311 ? 24.346 47.533 37.504 1.00 12.94 ? 311 VAL A CG1 1 ATOM 2368 C CG2 . VAL A 1 311 ? 25.328 48.097 35.215 1.00 11.88 ? 311 VAL A CG2 1 ATOM 2369 N N . ALA A 1 312 ? 21.432 47.390 36.112 1.00 10.06 ? 312 ALA A N 1 ATOM 2370 C CA . ALA A 1 312 ? 20.580 46.358 35.515 1.00 10.64 ? 312 ALA A CA 1 ATOM 2371 C C . ALA A 1 312 ? 19.609 46.928 34.487 1.00 11.38 ? 312 ALA A C 1 ATOM 2372 O O . ALA A 1 312 ? 19.470 46.383 33.422 1.00 11.27 ? 312 ALA A O 1 ATOM 2373 C CB . ALA A 1 312 ? 19.837 45.518 36.598 1.00 11.91 ? 312 ALA A CB 1 ATOM 2374 N N . ALA A 1 313 ? 18.931 48.027 34.817 1.00 10.99 ? 313 ALA A N 1 ATOM 2375 C CA . ALA A 1 313 ? 17.954 48.639 33.910 1.00 10.60 ? 313 ALA A CA 1 ATOM 2376 C C . ALA A 1 313 ? 18.679 49.249 32.713 1.00 12.57 ? 313 ALA A C 1 ATOM 2377 O O . ALA A 1 313 ? 18.192 49.142 31.605 1.00 12.51 ? 313 ALA A O 1 ATOM 2378 C CB . ALA A 1 313 ? 17.168 49.698 34.655 1.00 12.76 ? 313 ALA A CB 1 ATOM 2379 N N . ARG A 1 314 ? 19.819 49.871 32.958 1.00 11.34 ? 314 ARG A N 1 ATOM 2380 C CA . ARG A 1 314 ? 20.581 50.461 31.841 1.00 10.35 ? 314 ARG A CA 1 ATOM 2381 C C . ARG A 1 314 ? 21.099 49.345 30.921 1.00 12.45 ? 314 ARG A C 1 ATOM 2382 O O . ARG A 1 314 ? 21.025 49.515 29.666 1.00 11.59 ? 314 ARG A O 1 ATOM 2383 C CB . ARG A 1 314 ? 21.759 51.248 32.417 1.00 10.59 ? 314 ARG A CB 1 ATOM 2384 C CG . ARG A 1 314 ? 21.414 52.451 33.286 1.00 13.09 ? 314 ARG A CG 1 ATOM 2385 C CD . ARG A 1 314 ? 21.132 53.715 32.476 1.00 15.94 ? 314 ARG A CD 1 ATOM 2386 N NE . ARG A 1 314 ? 19.796 53.736 31.924 1.00 17.57 ? 314 ARG A NE 1 ATOM 2387 C CZ . ARG A 1 314 ? 19.324 54.662 31.093 1.00 17.21 ? 314 ARG A CZ 1 ATOM 2388 N NH1 . ARG A 1 314 ? 20.134 55.664 30.675 1.00 16.16 ? 314 ARG A NH1 1 ATOM 2389 N NH2 . ARG A 1 314 ? 18.028 54.687 30.764 1.00 18.11 ? 314 ARG A NH2 1 ATOM 2390 N N . SER A 1 315 ? 21.560 48.212 31.473 1.00 11.81 ? 315 SER A N 1 ATOM 2391 C CA . SER A 1 315 ? 22.017 47.086 30.653 1.00 12.78 ? 315 SER A CA 1 ATOM 2392 C C . SER A 1 315 ? 20.858 46.492 29.910 1.00 13.42 ? 315 SER A C 1 ATOM 2393 O O . SER A 1 315 ? 20.978 46.073 28.746 1.00 13.31 ? 315 SER A O 1 ATOM 2394 C CB . SER A 1 315 ? 22.685 46.005 31.530 1.00 10.57 ? 315 SER A CB 1 ATOM 2395 O OG . SER A 1 315 ? 23.845 46.491 32.157 1.00 12.39 ? 315 SER A OG 1 ATOM 2396 N N . ASP A 1 316 ? 19.685 46.400 30.548 1.00 12.99 ? 316 ASP A N 1 ATOM 2397 C CA . ASP A 1 316 ? 18.512 45.848 29.853 1.00 14.20 ? 316 ASP A CA 1 ATOM 2398 C C . ASP A 1 316 ? 18.277 46.665 28.563 1.00 11.87 ? 316 ASP A C 1 ATOM 2399 O O . ASP A 1 316 ? 18.017 46.112 27.476 1.00 12.14 ? 316 ASP A O 1 ATOM 2400 C CB . ASP A 1 316 ? 17.212 45.989 30.701 1.00 14.76 ? 316 ASP A CB 1 ATOM 2401 C CG . ASP A 1 316 ? 17.141 45.090 31.919 1.00 15.92 ? 316 ASP A CG 1 ATOM 2402 O OD1 . ASP A 1 316 ? 17.846 44.067 31.974 1.00 18.16 ? 316 ASP A OD1 1 ATOM 2403 O OD2 . ASP A 1 316 ? 16.299 45.451 32.811 1.00 16.48 ? 316 ASP A OD2 1 ATOM 2404 N N . LEU A 1 317 ? 18.335 47.988 28.697 1.00 10.80 ? 317 LEU A N 1 ATOM 2405 C CA . LEU A 1 317 ? 18.106 48.867 27.534 1.00 11.21 ? 317 LEU A CA 1 ATOM 2406 C C . LEU A 1 317 ? 19.178 48.738 26.472 1.00 10.53 ? 317 LEU A C 1 ATOM 2407 O O . LEU A 1 317 ? 18.859 48.596 25.299 1.00 11.61 ? 317 LEU A O 1 ATOM 2408 C CB . LEU A 1 317 ? 18.054 50.333 27.955 1.00 14.52 ? 317 LEU A CB 1 ATOM 2409 C CG . LEU A 1 317 ? 16.752 50.814 28.530 1.00 17.13 ? 317 LEU A CG 1 ATOM 2410 C CD1 . LEU A 1 317 ? 17.029 52.180 29.167 1.00 21.42 ? 317 LEU A CD1 1 ATOM 2411 C CD2 . LEU A 1 317 ? 15.695 50.984 27.427 1.00 17.41 ? 317 LEU A CD2 1 ATOM 2412 N N . LEU A 1 318 ? 20.427 48.674 26.898 1.00 10.20 ? 318 LEU A N 1 ATOM 2413 C CA . LEU A 1 318 ? 21.516 48.650 25.935 1.00 9.96 ? 318 LEU A CA 1 ATOM 2414 C C . LEU A 1 318 ? 21.590 47.321 25.238 1.00 11.68 ? 318 LEU A C 1 ATOM 2415 O O . LEU A 1 318 ? 21.717 47.278 23.984 1.00 11.24 ? 318 LEU A O 1 ATOM 2416 C CB . LEU A 1 318 ? 22.820 48.957 26.676 1.00 10.64 ? 318 LEU A CB 1 ATOM 2417 C CG . LEU A 1 318 ? 24.078 49.036 25.782 1.00 11.98 ? 318 LEU A CG 1 ATOM 2418 C CD1 . LEU A 1 318 ? 23.856 50.163 24.759 1.00 12.44 ? 318 LEU A CD1 1 ATOM 2419 C CD2 . LEU A 1 318 ? 25.295 49.320 26.661 1.00 12.55 ? 318 LEU A CD2 1 ATOM 2420 N N . VAL A 1 319 ? 21.456 46.198 25.965 1.00 9.98 ? 319 VAL A N 1 ATOM 2421 C CA . VAL A 1 319 ? 21.544 44.879 25.332 1.00 10.63 ? 319 VAL A CA 1 ATOM 2422 C C . VAL A 1 319 ? 20.398 44.732 24.331 1.00 9.86 ? 319 VAL A C 1 ATOM 2423 O O . VAL A 1 319 ? 20.604 44.128 23.267 1.00 9.94 ? 319 VAL A O 1 ATOM 2424 C CB . VAL A 1 319 ? 21.574 43.727 26.389 1.00 10.14 ? 319 VAL A CB 1 ATOM 2425 C CG1 . VAL A 1 319 ? 21.452 42.362 25.706 1.00 11.35 ? 319 VAL A CG1 1 ATOM 2426 C CG2 . VAL A 1 319 ? 22.881 43.832 27.166 1.00 12.25 ? 319 VAL A CG2 1 ATOM 2427 N N . ASP A 1 320 ? 19.203 45.246 24.645 1.00 10.65 ? 320 ASP A N 1 ATOM 2428 C CA . ASP A 1 320 ? 18.085 45.174 23.704 1.00 9.64 ? 320 ASP A CA 1 ATOM 2429 C C . ASP A 1 320 ? 18.445 45.921 22.390 1.00 9.65 ? 320 ASP A C 1 ATOM 2430 O O . ASP A 1 320 ? 18.122 45.412 21.318 1.00 10.47 ? 320 ASP A O 1 ATOM 2431 C CB . ASP A 1 320 ? 16.820 45.741 24.396 1.00 12.24 ? 320 ASP A CB 1 ATOM 2432 C CG . ASP A 1 320 ? 15.649 45.877 23.469 1.00 12.68 ? 320 ASP A CG 1 ATOM 2433 O OD1 . ASP A 1 320 ? 15.084 44.806 23.107 1.00 15.84 ? 320 ASP A OD1 1 ATOM 2434 O OD2 . ASP A 1 320 ? 15.265 47.012 23.076 1.00 12.67 ? 320 ASP A OD2 1 ATOM 2435 N N . GLN A 1 321 ? 19.069 47.102 22.502 1.00 9.61 ? 321 GLN A N 1 ATOM 2436 C CA . GLN A 1 321 ? 19.524 47.804 21.262 1.00 9.22 ? 321 GLN A CA 1 ATOM 2437 C C . GLN A 1 321 ? 20.536 46.929 20.498 1.00 7.45 ? 321 GLN A C 1 ATOM 2438 O O . GLN A 1 321 ? 20.444 46.772 19.278 1.00 8.76 ? 321 GLN A O 1 ATOM 2439 C CB . GLN A 1 321 ? 20.189 49.135 21.639 1.00 9.37 ? 321 GLN A CB 1 ATOM 2440 C CG . GLN A 1 321 ? 19.175 50.202 22.081 1.00 9.12 ? 321 GLN A CG 1 ATOM 2441 C CD . GLN A 1 321 ? 18.102 50.423 20.971 1.00 12.10 ? 321 GLN A CD 1 ATOM 2442 O OE1 . GLN A 1 321 ? 18.429 50.816 19.855 1.00 12.45 ? 321 GLN A OE1 1 ATOM 2443 N NE2 . GLN A 1 321 ? 16.819 50.150 21.274 1.00 12.64 ? 321 GLN A NE2 1 ATOM 2444 N N . TRP A 1 322 ? 21.522 46.371 21.204 1.00 8.40 ? 322 TRP A N 1 ATOM 2445 C CA . TRP A 1 322 ? 22.516 45.531 20.550 1.00 8.95 ? 322 TRP A CA 1 ATOM 2446 C C . TRP A 1 322 ? 21.907 44.326 19.864 1.00 9.05 ? 322 TRP A C 1 ATOM 2447 O O . TRP A 1 322 ? 22.301 43.976 18.734 1.00 9.48 ? 322 TRP A O 1 ATOM 2448 C CB . TRP A 1 322 ? 23.551 45.013 21.564 1.00 8.22 ? 322 TRP A CB 1 ATOM 2449 C CG . TRP A 1 322 ? 24.467 46.071 22.124 1.00 9.25 ? 322 TRP A CG 1 ATOM 2450 C CD1 . TRP A 1 322 ? 24.667 47.360 21.679 1.00 10.14 ? 322 TRP A CD1 1 ATOM 2451 C CD2 . TRP A 1 322 ? 25.385 45.892 23.237 1.00 8.63 ? 322 TRP A CD2 1 ATOM 2452 N NE1 . TRP A 1 322 ? 25.656 47.990 22.452 1.00 10.86 ? 322 TRP A NE1 1 ATOM 2453 C CE2 . TRP A 1 322 ? 26.103 47.094 23.401 1.00 9.71 ? 322 TRP A CE2 1 ATOM 2454 C CE3 . TRP A 1 322 ? 25.656 44.821 24.108 1.00 9.67 ? 322 TRP A CE3 1 ATOM 2455 C CZ2 . TRP A 1 322 ? 27.084 47.269 24.416 1.00 10.62 ? 322 TRP A CZ2 1 ATOM 2456 C CZ3 . TRP A 1 322 ? 26.615 44.998 25.115 1.00 10.54 ? 322 TRP A CZ3 1 ATOM 2457 C CH2 . TRP A 1 322 ? 27.300 46.188 25.260 1.00 11.10 ? 322 TRP A CH2 1 ATOM 2458 N N . LYS A 1 323 ? 20.943 43.674 20.514 1.00 9.26 ? 323 LYS A N 1 ATOM 2459 C CA . LYS A 1 323 ? 20.339 42.473 19.906 1.00 9.45 ? 323 LYS A CA 1 ATOM 2460 C C . LYS A 1 323 ? 19.481 42.847 18.712 1.00 9.77 ? 323 LYS A C 1 ATOM 2461 O O . LYS A 1 323 ? 19.398 42.067 17.766 1.00 10.86 ? 323 LYS A O 1 ATOM 2462 C CB . LYS A 1 323 ? 19.520 41.640 20.941 1.00 10.81 ? 323 LYS A CB 1 ATOM 2463 C CG . LYS A 1 323 ? 20.521 40.981 21.947 1.00 13.00 ? 323 LYS A CG 1 ATOM 2464 C CD . LYS A 1 323 ? 19.859 39.926 22.866 1.00 13.91 ? 323 LYS A CD 1 ATOM 2465 C CE . LYS A 1 323 ? 20.920 39.171 23.637 1.00 14.22 ? 323 LYS A CE 1 ATOM 2466 N NZ . LYS A 1 323 ? 20.207 38.127 24.413 1.00 18.48 ? 323 LYS A NZ 1 ATOM 2467 N N . LYS A 1 324 ? 18.913 44.018 18.714 1.00 9.86 ? 324 LYS A N 1 ATOM 2468 C CA . LYS A 1 324 ? 18.193 44.471 17.514 1.00 8.22 ? 324 LYS A CA 1 ATOM 2469 C C . LYS A 1 324 ? 19.193 44.738 16.388 1.00 9.25 ? 324 LYS A C 1 ATOM 2470 O O . LYS A 1 324 ? 18.969 44.308 15.254 1.00 10.14 ? 324 LYS A O 1 ATOM 2471 C CB . LYS A 1 324 ? 17.392 45.738 17.828 1.00 9.55 ? 324 LYS A CB 1 ATOM 2472 C CG . LYS A 1 324 ? 16.119 45.391 18.646 1.00 9.88 ? 324 LYS A CG 1 ATOM 2473 C CD . LYS A 1 324 ? 15.516 46.654 19.250 1.00 11.40 ? 324 LYS A CD 1 ATOM 2474 C CE . LYS A 1 324 ? 14.218 46.256 19.971 1.00 12.18 ? 324 LYS A CE 1 ATOM 2475 N NZ . LYS A 1 324 ? 13.644 47.344 20.819 1.00 13.15 ? 324 LYS A NZ 1 ATOM 2476 N N . LYS A 1 325 ? 20.267 45.464 16.679 1.00 9.26 ? 325 LYS A N 1 ATOM 2477 C CA . LYS A 1 325 ? 21.293 45.701 15.632 1.00 8.42 ? 325 LYS A CA 1 ATOM 2478 C C . LYS A 1 325 ? 21.793 44.354 15.096 1.00 8.03 ? 325 LYS A C 1 ATOM 2479 O O . LYS A 1 325 ? 22.020 44.161 13.860 1.00 9.17 ? 325 LYS A O 1 ATOM 2480 C CB . LYS A 1 325 ? 22.454 46.505 16.229 1.00 8.23 ? 325 LYS A CB 1 ATOM 2481 C CG . LYS A 1 325 ? 23.382 47.097 15.061 1.00 8.18 ? 325 LYS A CG 1 ATOM 2482 C CD . LYS A 1 325 ? 24.503 47.925 15.677 1.00 8.95 ? 325 LYS A CD 1 ATOM 2483 C CE . LYS A 1 325 ? 25.281 48.622 14.512 1.00 9.97 ? 325 LYS A CE 1 ATOM 2484 N NZ . LYS A 1 325 ? 26.483 49.285 15.128 1.00 11.02 ? 325 LYS A NZ 1 ATOM 2485 N N . ALA A 1 326 ? 22.060 43.373 15.974 1.00 8.93 ? 326 ALA A N 1 ATOM 2486 C CA . ALA A 1 326 ? 22.579 42.081 15.549 1.00 9.51 ? 326 ALA A CA 1 ATOM 2487 C C . ALA A 1 326 ? 21.667 41.302 14.619 1.00 9.31 ? 326 ALA A C 1 ATOM 2488 O O . ALA A 1 326 ? 22.125 40.456 13.851 1.00 10.79 ? 326 ALA A O 1 ATOM 2489 C CB . ALA A 1 326 ? 22.894 41.223 16.808 1.00 11.69 ? 326 ALA A CB 1 ATOM 2490 N N . GLU A 1 327 ? 20.375 41.600 14.691 1.00 10.91 ? 327 GLU A N 1 ATOM 2491 C CA . GLU A 1 327 ? 19.430 40.932 13.782 1.00 11.97 ? 327 GLU A CA 1 ATOM 2492 C C . GLU A 1 327 ? 19.673 41.263 12.324 1.00 11.87 ? 327 GLU A C 1 ATOM 2493 O O . GLU A 1 327 ? 19.212 40.542 11.449 1.00 14.63 ? 327 GLU A O 1 ATOM 2494 C CB . GLU A 1 327 ? 18.008 41.375 14.118 1.00 15.63 ? 327 GLU A CB 1 ATOM 2495 C CG . GLU A 1 327 ? 17.295 40.557 15.127 1.00 22.50 ? 327 GLU A CG 1 ATOM 2496 C CD . GLU A 1 327 ? 17.299 39.041 14.840 1.00 17.38 ? 327 GLU A CD 1 ATOM 2497 O OE1 . GLU A 1 327 ? 16.728 38.479 13.900 1.00 21.67 ? 327 GLU A OE1 1 ATOM 2498 O OE2 . GLU A 1 327 ? 17.948 38.396 15.601 1.00 18.98 ? 327 GLU A OE2 1 ATOM 2499 N N . LEU A 1 328 ? 20.366 42.379 12.058 1.00 10.82 ? 328 LEU A N 1 ATOM 2500 C CA . LEU A 1 328 ? 20.608 42.833 10.687 1.00 9.18 ? 328 LEU A CA 1 ATOM 2501 C C . LEU A 1 328 ? 21.832 42.190 10.065 1.00 10.91 ? 328 LEU A C 1 ATOM 2502 O O . LEU A 1 328 ? 22.097 42.453 8.878 1.00 11.76 ? 328 LEU A O 1 ATOM 2503 C CB . LEU A 1 328 ? 20.787 44.363 10.697 1.00 10.53 ? 328 LEU A CB 1 ATOM 2504 C CG . LEU A 1 328 ? 19.660 45.136 11.398 1.00 9.63 ? 328 LEU A CG 1 ATOM 2505 C CD1 . LEU A 1 328 ? 19.894 46.642 11.201 1.00 10.45 ? 328 LEU A CD1 1 ATOM 2506 C CD2 . LEU A 1 328 ? 18.269 44.800 10.881 1.00 11.57 ? 328 LEU A CD2 1 ATOM 2507 N N . TYR A 1 329 ? 22.568 41.358 10.803 1.00 9.94 ? 329 TYR A N 1 ATOM 2508 C CA . TYR A 1 329 ? 23.808 40.751 10.328 1.00 9.87 ? 329 TYR A CA 1 ATOM 2509 C C . TYR A 1 329 ? 23.788 39.249 10.533 1.00 10.67 ? 329 TYR A C 1 ATOM 2510 O O . TYR A 1 329 ? 22.931 38.745 11.295 1.00 11.93 ? 329 TYR A O 1 ATOM 2511 C CB . TYR A 1 329 ? 25.025 41.365 11.058 1.00 9.74 ? 329 TYR A CB 1 ATOM 2512 C CG . TYR A 1 329 ? 25.214 42.853 10.716 1.00 9.29 ? 329 TYR A CG 1 ATOM 2513 C CD1 . TYR A 1 329 ? 25.977 43.213 9.604 1.00 9.74 ? 329 TYR A CD1 1 ATOM 2514 C CD2 . TYR A 1 329 ? 24.632 43.862 11.471 1.00 10.54 ? 329 TYR A CD2 1 ATOM 2515 C CE1 . TYR A 1 329 ? 26.144 44.580 9.235 1.00 9.62 ? 329 TYR A CE1 1 ATOM 2516 C CE2 . TYR A 1 329 ? 24.809 45.233 11.128 1.00 11.09 ? 329 TYR A CE2 1 ATOM 2517 C CZ . TYR A 1 329 ? 25.541 45.553 10.022 1.00 9.84 ? 329 TYR A CZ 1 ATOM 2518 O OH . TYR A 1 329 ? 25.608 46.890 9.683 1.00 10.97 ? 329 TYR A OH 1 ATOM 2519 N N . ARG A 1 330 ? 24.695 38.545 9.883 1.00 10.07 ? 330 ARG A N 1 ATOM 2520 C CA . ARG A 1 330 ? 24.676 37.096 9.883 1.00 10.04 ? 330 ARG A CA 1 ATOM 2521 C C . ARG A 1 330 ? 25.501 36.351 10.915 1.00 12.05 ? 330 ARG A C 1 ATOM 2522 O O . ARG A 1 330 ? 25.294 35.122 11.026 1.00 13.58 ? 330 ARG A O 1 ATOM 2523 C CB . ARG A 1 330 ? 25.077 36.622 8.460 1.00 11.08 ? 330 ARG A CB 1 ATOM 2524 C CG . ARG A 1 330 ? 24.110 37.070 7.354 1.00 10.02 ? 330 ARG A CG 1 ATOM 2525 C CD . ARG A 1 330 ? 24.505 36.534 6.004 1.00 11.43 ? 330 ARG A CD 1 ATOM 2526 N NE . ARG A 1 330 ? 23.540 37.079 5.042 1.00 13.14 ? 330 ARG A NE 1 ATOM 2527 C CZ . ARG A 1 330 ? 23.230 36.547 3.857 1.00 14.65 ? 330 ARG A CZ 1 ATOM 2528 N NH1 . ARG A 1 330 ? 23.811 35.437 3.440 1.00 14.76 ? 330 ARG A NH1 1 ATOM 2529 N NH2 . ARG A 1 330 ? 22.343 37.173 3.082 1.00 15.00 ? 330 ARG A NH2 1 ATOM 2530 N N . THR A 1 331 ? 26.443 36.993 11.608 1.00 11.39 ? 331 THR A N 1 ATOM 2531 C CA . THR A 1 331 ? 27.230 36.232 12.593 1.00 10.57 ? 331 THR A CA 1 ATOM 2532 C C . THR A 1 331 ? 26.805 36.626 14.001 1.00 10.60 ? 331 THR A C 1 ATOM 2533 O O . THR A 1 331 ? 25.950 37.493 14.198 1.00 13.73 ? 331 THR A O 1 ATOM 2534 C CB . THR A 1 331 ? 28.776 36.472 12.442 1.00 10.42 ? 331 THR A CB 1 ATOM 2535 O OG1 . THR A 1 331 ? 29.109 37.773 12.941 1.00 10.70 ? 331 THR A OG1 1 ATOM 2536 C CG2 . THR A 1 331 ? 29.213 36.322 10.912 1.00 11.73 ? 331 THR A CG2 1 ATOM 2537 N N . ASN A 1 332 ? 27.434 35.973 14.975 1.00 10.90 ? 332 ASN A N 1 ATOM 2538 C CA . ASN A 1 332 ? 27.197 36.306 16.381 1.00 10.14 ? 332 ASN A CA 1 ATOM 2539 C C . ASN A 1 332 ? 28.287 37.264 16.887 1.00 11.40 ? 332 ASN A C 1 ATOM 2540 O O . ASN A 1 332 ? 28.599 37.280 18.103 1.00 11.69 ? 332 ASN A O 1 ATOM 2541 C CB . ASN A 1 332 ? 27.185 35.026 17.271 1.00 12.22 ? 332 ASN A CB 1 ATOM 2542 C CG . ASN A 1 332 ? 28.556 34.350 17.349 1.00 14.80 ? 332 ASN A CG 1 ATOM 2543 O OD1 . ASN A 1 332 ? 29.347 34.378 16.425 1.00 16.38 ? 332 ASN A OD1 1 ATOM 2544 N ND2 . ASN A 1 332 ? 28.844 33.663 18.490 1.00 18.96 ? 332 ASN A ND2 1 ATOM 2545 N N . VAL A 1 333 ? 28.910 38.046 15.981 1.00 9.37 ? 333 VAL A N 1 ATOM 2546 C CA . VAL A 1 333 ? 29.945 39.042 16.359 1.00 10.24 ? 333 VAL A CA 1 ATOM 2547 C C . VAL A 1 333 ? 29.394 40.413 15.949 1.00 9.22 ? 333 VAL A C 1 ATOM 2548 O O . VAL A 1 333 ? 29.072 40.585 14.753 1.00 10.27 ? 333 VAL A O 1 ATOM 2549 C CB . VAL A 1 333 ? 31.215 38.776 15.616 1.00 10.33 ? 333 VAL A CB 1 ATOM 2550 C CG1 . VAL A 1 333 ? 32.248 39.808 16.058 1.00 11.48 ? 333 VAL A CG1 1 ATOM 2551 C CG2 . VAL A 1 333 ? 31.675 37.322 15.863 1.00 11.89 ? 333 VAL A CG2 1 ATOM 2552 N N . LEU A 1 334 ? 29.241 41.364 16.876 1.00 7.99 ? 334 LEU A N 1 ATOM 2553 C CA . LEU A 1 334 ? 28.621 42.650 16.616 1.00 8.10 ? 334 LEU A CA 1 ATOM 2554 C C . LEU A 1 334 ? 29.600 43.809 16.803 1.00 7.88 ? 334 LEU A C 1 ATOM 2555 O O . LEU A 1 334 ? 30.341 43.897 17.784 1.00 8.69 ? 334 LEU A O 1 ATOM 2556 C CB . LEU A 1 334 ? 27.465 42.837 17.619 1.00 8.46 ? 334 LEU A CB 1 ATOM 2557 C CG . LEU A 1 334 ? 26.655 44.128 17.430 1.00 8.74 ? 334 LEU A CG 1 ATOM 2558 C CD1 . LEU A 1 334 ? 25.838 44.040 16.104 1.00 10.11 ? 334 LEU A CD1 1 ATOM 2559 C CD2 . LEU A 1 334 ? 25.671 44.289 18.628 1.00 9.29 ? 334 LEU A CD2 1 ATOM 2560 N N . LEU A 1 335 ? 29.626 44.709 15.822 1.00 8.08 ? 335 LEU A N 1 ATOM 2561 C CA . LEU A 1 335 ? 30.462 45.909 15.845 1.00 7.82 ? 335 LEU A CA 1 ATOM 2562 C C . LEU A 1 335 ? 29.662 47.077 16.399 1.00 7.14 ? 335 LEU A C 1 ATOM 2563 O O . LEU A 1 335 ? 28.615 47.422 15.840 1.00 9.02 ? 335 LEU A O 1 ATOM 2564 C CB . LEU A 1 335 ? 30.904 46.251 14.399 1.00 8.00 ? 335 LEU A CB 1 ATOM 2565 C CG . LEU A 1 335 ? 31.788 47.512 14.324 1.00 7.35 ? 335 LEU A CG 1 ATOM 2566 C CD1 . LEU A 1 335 ? 33.083 47.339 15.022 1.00 10.02 ? 335 LEU A CD1 1 ATOM 2567 C CD2 . LEU A 1 335 ? 31.997 47.829 12.862 1.00 9.85 ? 335 LEU A CD2 1 ATOM 2568 N N . ILE A 1 336 ? 30.162 47.715 17.456 1.00 7.11 ? 336 ILE A N 1 ATOM 2569 C CA . ILE A 1 336 ? 29.559 48.889 18.047 1.00 7.18 ? 336 ILE A CA 1 ATOM 2570 C C . ILE A 1 336 ? 30.592 50.039 18.089 1.00 7.06 ? 336 ILE A C 1 ATOM 2571 O O . ILE A 1 336 ? 31.383 50.154 19.019 1.00 7.67 ? 336 ILE A O 1 ATOM 2572 C CB . ILE A 1 336 ? 29.033 48.616 19.498 1.00 8.39 ? 336 ILE A CB 1 ATOM 2573 C CG1 . ILE A 1 336 ? 27.991 47.493 19.496 1.00 7.61 ? 336 ILE A CG1 1 ATOM 2574 C CG2 . ILE A 1 336 ? 28.489 49.939 20.069 1.00 9.47 ? 336 ILE A CG2 1 ATOM 2575 C CD1 . ILE A 1 336 ? 26.706 47.813 18.724 1.00 9.18 ? 336 ILE A CD1 1 ATOM 2576 N N . PRO A 1 337 ? 30.624 50.887 17.052 1.00 7.56 ? 337 PRO A N 1 ATOM 2577 C CA . PRO A 1 337 ? 31.552 52.038 17.101 1.00 7.28 ? 337 PRO A CA 1 ATOM 2578 C C . PRO A 1 337 ? 31.136 52.955 18.283 1.00 7.60 ? 337 PRO A C 1 ATOM 2579 O O . PRO A 1 337 ? 29.946 53.090 18.580 1.00 9.08 ? 337 PRO A O 1 ATOM 2580 C CB . PRO A 1 337 ? 31.265 52.760 15.771 1.00 8.14 ? 337 PRO A CB 1 ATOM 2581 C CG . PRO A 1 337 ? 30.832 51.634 14.836 1.00 8.40 ? 337 PRO A CG 1 ATOM 2582 C CD . PRO A 1 337 ? 29.884 50.822 15.777 1.00 8.16 ? 337 PRO A CD 1 ATOM 2583 N N . LEU A 1 338 ? 32.121 53.588 18.926 1.00 6.96 ? 338 LEU A N 1 ATOM 2584 C CA . LEU A 1 338 ? 31.886 54.520 20.022 1.00 7.70 ? 338 LEU A CA 1 ATOM 2585 C C . LEU A 1 338 ? 32.694 55.804 19.792 1.00 7.54 ? 338 LEU A C 1 ATOM 2586 O O . LEU A 1 338 ? 33.850 55.895 20.211 1.00 7.19 ? 338 LEU A O 1 ATOM 2587 C CB . LEU A 1 338 ? 32.231 53.854 21.356 1.00 8.93 ? 338 LEU A CB 1 ATOM 2588 C CG . LEU A 1 338 ? 31.862 54.754 22.529 1.00 8.50 ? 338 LEU A CG 1 ATOM 2589 C CD1 . LEU A 1 338 ? 30.351 54.668 22.832 1.00 11.67 ? 338 LEU A CD1 1 ATOM 2590 C CD2 . LEU A 1 338 ? 32.650 54.272 23.798 1.00 11.71 ? 338 LEU A CD2 1 ATOM 2591 N N . GLY A 1 339 ? 32.093 56.784 19.111 1.00 6.83 ? 339 GLY A N 1 ATOM 2592 C CA . GLY A 1 339 ? 32.869 57.986 18.818 1.00 7.30 ? 339 GLY A CA 1 ATOM 2593 C C . GLY A 1 339 ? 32.064 58.983 18.020 1.00 7.79 ? 339 GLY A C 1 ATOM 2594 O O . GLY A 1 339 ? 30.888 58.769 17.729 1.00 9.16 ? 339 GLY A O 1 ATOM 2595 N N . ASP A 1 340 ? 32.722 60.107 17.674 1.00 7.75 ? 340 ASP A N 1 ATOM 2596 C CA . ASP A 1 340 ? 32.088 61.201 16.927 1.00 7.04 ? 340 ASP A CA 1 ATOM 2597 C C . ASP A 1 340 ? 33.261 62.127 16.552 1.00 6.50 ? 340 ASP A C 1 ATOM 2598 O O . ASP A 1 340 ? 34.428 61.826 16.759 1.00 7.36 ? 340 ASP A O 1 ATOM 2599 C CB . ASP A 1 340 ? 31.025 61.869 17.854 1.00 8.20 ? 340 ASP A CB 1 ATOM 2600 C CG . ASP A 1 340 ? 29.939 62.631 17.135 1.00 9.31 ? 340 ASP A CG 1 ATOM 2601 O OD1 . ASP A 1 340 ? 30.096 62.954 15.911 1.00 9.89 ? 340 ASP A OD1 1 ATOM 2602 O OD2 . ASP A 1 340 ? 28.917 62.918 17.820 1.00 9.90 ? 340 ASP A OD2 1 ATOM 2603 N N . ASP A 1 341 ? 32.889 63.297 16.055 1.00 7.36 ? 341 ASP A N 1 ATOM 2604 C CA . ASP A 1 341 ? 33.893 64.267 15.522 1.00 7.37 ? 341 ASP A CA 1 ATOM 2605 C C . ASP A 1 341 ? 34.759 64.814 16.625 1.00 7.09 ? 341 ASP A C 1 ATOM 2606 O O . ASP A 1 341 ? 34.228 65.292 17.659 1.00 8.93 ? 341 ASP A O 1 ATOM 2607 C CB . ASP A 1 341 ? 33.187 65.460 14.831 1.00 8.54 ? 341 ASP A CB 1 ATOM 2608 C CG . ASP A 1 341 ? 32.464 65.067 13.562 1.00 8.77 ? 341 ASP A CG 1 ATOM 2609 O OD1 . ASP A 1 341 ? 32.434 63.858 13.223 1.00 11.02 ? 341 ASP A OD1 1 ATOM 2610 O OD2 . ASP A 1 341 ? 31.993 66.028 12.876 1.00 11.97 ? 341 ASP A OD2 1 ATOM 2611 N N . PHE A 1 342 ? 36.070 64.712 16.427 1.00 7.23 ? 342 PHE A N 1 ATOM 2612 C CA . PHE A 1 342 ? 37.039 65.248 17.374 1.00 7.34 ? 342 PHE A CA 1 ATOM 2613 C C . PHE A 1 342 ? 36.742 64.862 18.840 1.00 7.89 ? 342 PHE A C 1 ATOM 2614 O O . PHE A 1 342 ? 36.978 65.672 19.776 1.00 10.33 ? 342 PHE A O 1 ATOM 2615 C CB . PHE A 1 342 ? 37.158 66.781 17.173 1.00 7.65 ? 342 PHE A CB 1 ATOM 2616 C CG . PHE A 1 342 ? 37.745 67.181 15.819 1.00 7.96 ? 342 PHE A CG 1 ATOM 2617 C CD1 . PHE A 1 342 ? 39.115 67.160 15.603 1.00 7.44 ? 342 PHE A CD1 1 ATOM 2618 C CD2 . PHE A 1 342 ? 36.900 67.594 14.762 1.00 7.95 ? 342 PHE A CD2 1 ATOM 2619 C CE1 . PHE A 1 342 ? 39.656 67.546 14.353 1.00 8.30 ? 342 PHE A CE1 1 ATOM 2620 C CE2 . PHE A 1 342 ? 37.437 67.986 13.486 1.00 8.60 ? 342 PHE A CE2 1 ATOM 2621 C CZ . PHE A 1 342 ? 38.797 67.959 13.308 1.00 8.46 ? 342 PHE A CZ 1 ATOM 2622 N N . ARG A 1 343 ? 36.309 63.606 19.011 1.00 7.64 ? 343 ARG A N 1 ATOM 2623 C CA . ARG A 1 343 ? 36.087 63.109 20.375 1.00 8.18 ? 343 ARG A CA 1 ATOM 2624 C C . ARG A 1 343 ? 37.405 62.678 21.025 1.00 10.03 ? 343 ARG A C 1 ATOM 2625 O O . ARG A 1 343 ? 38.497 62.585 20.414 1.00 8.61 ? 343 ARG A O 1 ATOM 2626 C CB . ARG A 1 343 ? 35.107 61.932 20.352 1.00 8.29 ? 343 ARG A CB 1 ATOM 2627 C CG . ARG A 1 343 ? 33.685 62.354 20.120 1.00 8.60 ? 343 ARG A CG 1 ATOM 2628 C CD . ARG A 1 343 ? 33.186 63.315 21.228 1.00 8.33 ? 343 ARG A CD 1 ATOM 2629 N NE . ARG A 1 343 ? 31.742 63.575 21.120 1.00 8.46 ? 343 ARG A NE 1 ATOM 2630 C CZ . ARG A 1 343 ? 30.801 62.867 21.751 1.00 8.38 ? 343 ARG A CZ 1 ATOM 2631 N NH1 . ARG A 1 343 ? 31.133 61.802 22.523 1.00 8.14 ? 343 ARG A NH1 1 ATOM 2632 N NH2 . ARG A 1 343 ? 29.532 63.266 21.682 1.00 8.13 ? 343 ARG A NH2 1 ATOM 2633 N N . PHE A 1 344 ? 37.267 62.361 22.311 1.00 10.78 ? 344 PHE A N 1 ATOM 2634 C CA . PHE A 1 344 ? 38.388 61.909 23.186 1.00 9.80 ? 344 PHE A CA 1 ATOM 2635 C C . PHE A 1 344 ? 39.483 62.940 23.313 1.00 11.27 ? 344 PHE A C 1 ATOM 2636 O O . PHE A 1 344 ? 40.684 62.642 23.324 1.00 12.86 ? 344 PHE A O 1 ATOM 2637 C CB . PHE A 1 344 ? 38.835 60.532 22.707 1.00 11.56 ? 344 PHE A CB 1 ATOM 2638 C CG . PHE A 1 344 ? 37.796 59.475 22.894 1.00 10.30 ? 344 PHE A CG 1 ATOM 2639 C CD1 . PHE A 1 344 ? 37.548 58.933 24.190 1.00 12.04 ? 344 PHE A CD1 1 ATOM 2640 C CD2 . PHE A 1 344 ? 37.013 59.023 21.857 1.00 10.05 ? 344 PHE A CD2 1 ATOM 2641 C CE1 . PHE A 1 344 ? 36.549 57.987 24.360 1.00 12.71 ? 344 PHE A CE1 1 ATOM 2642 C CE2 . PHE A 1 344 ? 36.023 58.092 22.026 1.00 11.34 ? 344 PHE A CE2 1 ATOM 2643 C CZ . PHE A 1 344 ? 35.786 57.567 23.306 1.00 10.89 ? 344 PHE A CZ 1 ATOM 2644 N N . LYS A 1 345 ? 39.081 64.176 23.487 1.00 11.41 ? 345 LYS A N 1 ATOM 2645 C CA . LYS A 1 345 ? 39.973 65.287 23.615 1.00 12.29 ? 345 LYS A CA 1 ATOM 2646 C C . LYS A 1 345 ? 40.481 65.581 25.033 1.00 14.24 ? 345 LYS A C 1 ATOM 2647 O O . LYS A 1 345 ? 41.659 65.960 25.178 1.00 18.10 ? 345 LYS A O 1 ATOM 2648 C CB . LYS A 1 345 ? 39.269 66.536 23.086 1.00 16.07 ? 345 LYS A CB 1 ATOM 2649 C CG . LYS A 1 345 ? 40.076 67.730 23.210 1.00 15.95 ? 345 LYS A CG 1 ATOM 2650 C CD . LYS A 1 345 ? 39.293 68.878 22.618 1.00 21.80 ? 345 LYS A CD 1 ATOM 2651 C CE . LYS A 1 345 ? 40.021 70.155 22.774 1.00 22.07 ? 345 LYS A CE 1 ATOM 2652 N NZ . LYS A 1 345 ? 39.184 71.287 22.200 1.00 22.71 ? 345 LYS A NZ 1 ATOM 2653 N N . GLN A 1 346 ? 39.572 65.492 25.994 1.00 14.74 ? 346 GLN A N 1 ATOM 2654 C CA . GLN A 1 346 ? 39.903 65.736 27.400 1.00 15.98 ? 346 GLN A CA 1 ATOM 2655 C C . GLN A 1 346 ? 40.047 64.455 28.185 1.00 15.39 ? 346 GLN A C 1 ATOM 2656 O O . GLN A 1 346 ? 39.326 63.486 27.949 1.00 11.98 ? 346 GLN A O 1 ATOM 2657 C CB . GLN A 1 346 ? 38.786 66.542 28.040 1.00 17.41 ? 346 GLN A CB 1 ATOM 2658 C CG . GLN A 1 346 ? 38.643 67.965 27.467 1.00 28.01 ? 346 GLN A CG 1 ATOM 2659 C CD . GLN A 1 346 ? 37.268 68.562 27.772 1.00 28.64 ? 346 GLN A CD 1 ATOM 2660 O OE1 . GLN A 1 346 ? 36.946 68.839 28.931 1.00 43.57 ? 346 GLN A OE1 1 ATOM 2661 N NE2 . GLN A 1 346 ? 36.434 68.734 26.736 1.00 35.94 ? 346 GLN A NE2 1 ATOM 2662 N N . ASN A 1 347 ? 40.941 64.464 29.161 1.00 15.60 ? 347 ASN A N 1 ATOM 2663 C CA . ASN A 1 347 ? 41.099 63.376 30.104 1.00 15.16 ? 347 ASN A CA 1 ATOM 2664 C C . ASN A 1 347 ? 39.795 62.937 30.740 1.00 13.33 ? 347 ASN A C 1 ATOM 2665 O O . ASN A 1 347 ? 39.527 61.759 30.864 1.00 13.15 ? 347 ASN A O 1 ATOM 2666 C CB . ASN A 1 347 ? 42.029 63.845 31.216 1.00 20.11 ? 347 ASN A CB 1 ATOM 2667 C CG . ASN A 1 347 ? 43.375 64.115 30.709 1.00 28.01 ? 347 ASN A CG 1 ATOM 2668 O OD1 . ASN A 1 347 ? 43.969 65.166 30.953 1.00 31.11 ? 347 ASN A OD1 1 ATOM 2669 N ND2 . ASN A 1 347 ? 43.887 63.163 29.969 1.00 34.32 ? 347 ASN A ND2 1 ATOM 2670 N N . THR A 1 348 ? 39.006 63.926 31.128 1.00 10.98 ? 348 THR A N 1 ATOM 2671 C CA . THR A 1 348 ? 37.743 63.673 31.789 1.00 12.29 ? 348 THR A CA 1 ATOM 2672 C C . THR A 1 348 ? 36.765 62.926 30.865 1.00 12.57 ? 348 THR A C 1 ATOM 2673 O O . THR A 1 348 ? 35.888 62.174 31.316 1.00 12.22 ? 348 THR A O 1 ATOM 2674 C CB . THR A 1 348 ? 37.077 64.949 32.257 1.00 15.96 ? 348 THR A CB 1 ATOM 2675 O OG1 . THR A 1 348 ? 37.080 65.892 31.181 1.00 18.30 ? 348 THR A OG1 1 ATOM 2676 C CG2 . THR A 1 348 ? 37.843 65.543 33.463 1.00 16.05 ? 348 THR A CG2 1 ATOM 2677 N N . GLU A 1 349 ? 36.870 63.145 29.558 1.00 10.21 ? 349 GLU A N 1 ATOM 2678 C CA . GLU A 1 349 ? 36.018 62.435 28.600 1.00 10.50 ? 349 GLU A CA 1 ATOM 2679 C C . GLU A 1 349 ? 36.428 60.979 28.458 1.00 8.42 ? 349 GLU A C 1 ATOM 2680 O O . GLU A 1 349 ? 35.594 60.108 28.427 1.00 9.16 ? 349 GLU A O 1 ATOM 2681 C CB . GLU A 1 349 ? 36.068 63.139 27.240 1.00 9.59 ? 349 GLU A CB 1 ATOM 2682 C CG . GLU A 1 349 ? 35.272 62.418 26.170 1.00 11.26 ? 349 GLU A CG 1 ATOM 2683 C CD . GLU A 1 349 ? 35.491 63.046 24.776 1.00 10.06 ? 349 GLU A CD 1 ATOM 2684 O OE1 . GLU A 1 349 ? 36.148 64.074 24.634 1.00 13.05 ? 349 GLU A OE1 1 ATOM 2685 O OE2 . GLU A 1 349 ? 34.977 62.422 23.860 1.00 13.03 ? 349 GLU A OE2 1 ATOM 2686 N N . TRP A 1 350 ? 37.739 60.753 28.372 1.00 8.66 ? 350 TRP A N 1 ATOM 2687 C CA . TRP A 1 350 ? 38.225 59.379 28.344 1.00 8.19 ? 350 TRP A CA 1 ATOM 2688 C C . TRP A 1 350 ? 37.688 58.635 29.581 1.00 9.15 ? 350 TRP A C 1 ATOM 2689 O O . TRP A 1 350 ? 37.172 57.528 29.495 1.00 9.77 ? 350 TRP A O 1 ATOM 2690 C CB . TRP A 1 350 ? 39.755 59.325 28.410 1.00 8.09 ? 350 TRP A CB 1 ATOM 2691 C CG . TRP A 1 350 ? 40.390 59.576 27.085 1.00 8.73 ? 350 TRP A CG 1 ATOM 2692 C CD1 . TRP A 1 350 ? 40.733 60.782 26.585 1.00 9.52 ? 350 TRP A CD1 1 ATOM 2693 C CD2 . TRP A 1 350 ? 40.692 58.587 26.094 1.00 9.54 ? 350 TRP A CD2 1 ATOM 2694 N NE1 . TRP A 1 350 ? 41.262 60.617 25.301 1.00 8.81 ? 350 TRP A NE1 1 ATOM 2695 C CE2 . TRP A 1 350 ? 41.211 59.286 24.981 1.00 8.79 ? 350 TRP A CE2 1 ATOM 2696 C CE3 . TRP A 1 350 ? 40.560 57.188 26.021 1.00 11.70 ? 350 TRP A CE3 1 ATOM 2697 C CZ2 . TRP A 1 350 ? 41.579 58.630 23.795 1.00 11.67 ? 350 TRP A CZ2 1 ATOM 2698 C CZ3 . TRP A 1 350 ? 40.941 56.553 24.815 1.00 12.73 ? 350 TRP A CZ3 1 ATOM 2699 C CH2 . TRP A 1 350 ? 41.425 57.289 23.736 1.00 12.07 ? 350 TRP A CH2 1 ATOM 2700 N N . ASP A 1 351 ? 37.765 59.273 30.762 1.00 9.98 ? 351 ASP A N 1 ATOM 2701 C CA . ASP A 1 351 ? 37.291 58.598 31.993 1.00 11.12 ? 351 ASP A CA 1 ATOM 2702 C C . ASP A 1 351 ? 35.800 58.376 31.983 1.00 9.35 ? 351 ASP A C 1 ATOM 2703 O O . ASP A 1 351 ? 35.349 57.265 32.351 1.00 11.04 ? 351 ASP A O 1 ATOM 2704 C CB . ASP A 1 351 ? 37.639 59.431 33.229 1.00 14.36 ? 351 ASP A CB 1 ATOM 2705 C CG . ASP A 1 351 ? 39.104 59.388 33.575 1.00 20.18 ? 351 ASP A CG 1 ATOM 2706 O OD1 . ASP A 1 351 ? 39.769 58.357 33.303 1.00 23.17 ? 351 ASP A OD1 1 ATOM 2707 O OD2 . ASP A 1 351 ? 39.558 60.374 34.193 1.00 29.32 ? 351 ASP A OD2 1 ATOM 2708 N N . VAL A 1 352 ? 35.013 59.356 31.587 1.00 9.44 ? 352 VAL A N 1 ATOM 2709 C CA . VAL A 1 352 ? 33.579 59.173 31.653 1.00 9.98 ? 352 VAL A CA 1 ATOM 2710 C C . VAL A 1 352 ? 33.084 58.081 30.704 1.00 10.46 ? 352 VAL A C 1 ATOM 2711 O O . VAL A 1 352 ? 32.205 57.290 31.055 1.00 12.24 ? 352 VAL A O 1 ATOM 2712 C CB . VAL A 1 352 ? 32.863 60.579 31.501 1.00 13.16 ? 352 VAL A CB 1 ATOM 2713 C CG1 . VAL A 1 352 ? 32.659 60.977 30.079 1.00 12.18 ? 352 VAL A CG1 1 ATOM 2714 C CG2 . VAL A 1 352 ? 31.575 60.587 32.319 1.00 16.15 ? 352 VAL A CG2 1 ATOM 2715 N N . GLN A 1 353 ? 33.683 57.971 29.506 1.00 8.67 ? 353 GLN A N 1 ATOM 2716 C CA . GLN A 1 353 ? 33.269 56.900 28.613 1.00 7.73 ? 353 GLN A CA 1 ATOM 2717 C C . GLN A 1 353 ? 33.800 55.551 29.098 1.00 8.86 ? 353 GLN A C 1 ATOM 2718 O O . GLN A 1 353 ? 33.018 54.589 29.210 1.00 9.78 ? 353 GLN A O 1 ATOM 2719 C CB . GLN A 1 353 ? 33.773 57.170 27.177 1.00 8.26 ? 353 GLN A CB 1 ATOM 2720 C CG . GLN A 1 353 ? 33.240 58.493 26.534 1.00 9.02 ? 353 GLN A CG 1 ATOM 2721 C CD . GLN A 1 353 ? 31.789 58.418 26.070 1.00 9.15 ? 353 GLN A CD 1 ATOM 2722 O OE1 . GLN A 1 353 ? 30.932 57.742 26.655 1.00 9.62 ? 353 GLN A OE1 1 ATOM 2723 N NE2 . GLN A 1 353 ? 31.456 59.195 25.035 1.00 9.68 ? 353 GLN A NE2 1 ATOM 2724 N N . ARG A 1 354 ? 35.080 55.475 29.420 1.00 7.83 ? 354 ARG A N 1 ATOM 2725 C CA . ARG A 1 354 ? 35.624 54.197 29.818 1.00 8.74 ? 354 ARG A CA 1 ATOM 2726 C C . ARG A 1 354 ? 34.997 53.627 31.083 1.00 10.30 ? 354 ARG A C 1 ATOM 2727 O O . ARG A 1 354 ? 34.630 52.444 31.096 1.00 9.71 ? 354 ARG A O 1 ATOM 2728 C CB . ARG A 1 354 ? 37.122 54.309 30.044 1.00 9.77 ? 354 ARG A CB 1 ATOM 2729 C CG . ARG A 1 354 ? 37.765 52.966 30.503 1.00 9.42 ? 354 ARG A CG 1 ATOM 2730 C CD . ARG A 1 354 ? 39.302 53.141 30.696 1.00 11.81 ? 354 ARG A CD 1 ATOM 2731 N NE . ARG A 1 354 ? 39.600 54.168 31.712 1.00 12.03 ? 354 ARG A NE 1 ATOM 2732 C CZ . ARG A 1 354 ? 39.487 54.006 33.034 1.00 14.47 ? 354 ARG A CZ 1 ATOM 2733 N NH1 . ARG A 1 354 ? 39.081 52.847 33.547 1.00 15.80 ? 354 ARG A NH1 1 ATOM 2734 N NH2 . ARG A 1 354 ? 39.825 54.996 33.823 1.00 15.19 ? 354 ARG A NH2 1 ATOM 2735 N N . VAL A 1 355 ? 34.873 54.434 32.132 1.00 9.49 ? 355 VAL A N 1 ATOM 2736 C CA . VAL A 1 355 ? 34.399 53.873 33.423 1.00 10.67 ? 355 VAL A CA 1 ATOM 2737 C C . VAL A 1 355 ? 32.943 53.435 33.315 1.00 10.79 ? 355 VAL A C 1 ATOM 2738 O O . VAL A 1 355 ? 32.588 52.338 33.813 1.00 11.11 ? 355 VAL A O 1 ATOM 2739 C CB . VAL A 1 355 ? 34.621 54.883 34.538 1.00 11.56 ? 355 VAL A CB 1 ATOM 2740 C CG1 . VAL A 1 355 ? 33.904 54.454 35.853 1.00 17.04 ? 355 VAL A CG1 1 ATOM 2741 C CG2 . VAL A 1 355 ? 36.154 55.075 34.815 1.00 14.38 ? 355 VAL A CG2 1 ATOM 2742 N N . ASN A 1 356 ? 32.076 54.251 32.701 1.00 9.23 ? 356 ASN A N 1 ATOM 2743 C CA . ASN A 1 356 ? 30.695 53.856 32.556 1.00 8.49 ? 356 ASN A CA 1 ATOM 2744 C C . ASN A 1 356 ? 30.537 52.588 31.695 1.00 9.44 ? 356 ASN A C 1 ATOM 2745 O O . ASN A 1 356 ? 29.783 51.651 32.072 1.00 9.37 ? 356 ASN A O 1 ATOM 2746 C CB . ASN A 1 356 ? 29.887 55.040 32.068 1.00 9.92 ? 356 ASN A CB 1 ATOM 2747 C CG . ASN A 1 356 ? 29.646 56.042 33.153 1.00 10.61 ? 356 ASN A CG 1 ATOM 2748 O OD1 . ASN A 1 356 ? 28.938 55.704 34.147 1.00 11.55 ? 356 ASN A OD1 1 ATOM 2749 N ND2 . ASN A 1 356 ? 30.273 57.237 33.083 1.00 11.45 ? 356 ASN A ND2 1 ATOM 2750 N N . TYR A 1 357 ? 31.260 52.473 30.575 1.00 8.54 ? 357 TYR A N 1 ATOM 2751 C CA . TYR A 1 357 ? 31.167 51.259 29.777 1.00 10.05 ? 357 TYR A CA 1 ATOM 2752 C C . TYR A 1 357 ? 31.736 50.094 30.542 1.00 8.88 ? 357 TYR A C 1 ATOM 2753 O O . TYR A 1 357 ? 31.160 48.987 30.439 1.00 9.71 ? 357 TYR A O 1 ATOM 2754 C CB . TYR A 1 357 ? 31.837 51.444 28.379 1.00 8.69 ? 357 TYR A CB 1 ATOM 2755 C CG . TYR A 1 357 ? 30.850 51.981 27.382 1.00 7.67 ? 357 TYR A CG 1 ATOM 2756 C CD1 . TYR A 1 357 ? 30.038 51.094 26.660 1.00 8.42 ? 357 TYR A CD1 1 ATOM 2757 C CD2 . TYR A 1 357 ? 30.692 53.359 27.207 1.00 8.07 ? 357 TYR A CD2 1 ATOM 2758 C CE1 . TYR A 1 357 ? 29.056 51.566 25.778 1.00 8.35 ? 357 TYR A CE1 1 ATOM 2759 C CE2 . TYR A 1 357 ? 29.716 53.866 26.321 1.00 8.81 ? 357 TYR A CE2 1 ATOM 2760 C CZ . TYR A 1 357 ? 28.906 52.956 25.624 1.00 8.11 ? 357 TYR A CZ 1 ATOM 2761 O OH . TYR A 1 357 ? 27.931 53.378 24.786 1.00 10.02 ? 357 TYR A OH 1 ATOM 2762 N N . GLU A 1 358 ? 32.808 50.269 31.322 1.00 9.17 ? 358 GLU A N 1 ATOM 2763 C CA . GLU A 1 358 ? 33.305 49.101 32.083 1.00 9.39 ? 358 GLU A CA 1 ATOM 2764 C C . GLU A 1 358 ? 32.303 48.616 33.141 1.00 9.96 ? 358 GLU A C 1 ATOM 2765 O O . GLU A 1 358 ? 32.205 47.402 33.332 1.00 10.02 ? 358 GLU A O 1 ATOM 2766 C CB . GLU A 1 358 ? 34.652 49.404 32.715 1.00 10.37 ? 358 GLU A CB 1 ATOM 2767 C CG . GLU A 1 358 ? 35.635 49.416 31.540 1.00 14.07 ? 358 GLU A CG 1 ATOM 2768 C CD . GLU A 1 358 ? 37.051 49.704 31.861 1.00 19.60 ? 358 GLU A CD 1 ATOM 2769 O OE1 . GLU A 1 358 ? 37.385 50.220 32.925 1.00 17.41 ? 358 GLU A OE1 1 ATOM 2770 O OE2 . GLU A 1 358 ? 37.888 49.450 30.954 1.00 21.91 ? 358 GLU A OE2 1 ATOM 2771 N N . ARG A 1 359 ? 31.563 49.512 33.779 1.00 9.07 ? 359 ARG A N 1 ATOM 2772 C CA . ARG A 1 359 ? 30.514 49.074 34.692 1.00 10.43 ? 359 ARG A CA 1 ATOM 2773 C C . ARG A 1 359 ? 29.442 48.259 33.953 1.00 10.04 ? 359 ARG A C 1 ATOM 2774 O O . ARG A 1 359 ? 28.997 47.227 34.441 1.00 10.42 ? 359 ARG A O 1 ATOM 2775 C CB . ARG A 1 359 ? 29.899 50.273 35.402 1.00 10.16 ? 359 ARG A CB 1 ATOM 2776 C CG . ARG A 1 359 ? 30.813 50.943 36.402 1.00 12.45 ? 359 ARG A CG 1 ATOM 2777 C CD . ARG A 1 359 ? 30.133 52.182 36.954 1.00 18.79 ? 359 ARG A CD 1 ATOM 2778 N NE . ARG A 1 359 ? 31.012 52.938 37.833 1.00 20.55 ? 359 ARG A NE 1 ATOM 2779 C CZ . ARG A 1 359 ? 31.079 54.264 37.856 1.00 23.59 ? 359 ARG A CZ 1 ATOM 2780 N NH1 . ARG A 1 359 ? 30.316 54.991 37.041 1.00 21.16 ? 359 ARG A NH1 1 ATOM 2781 N NH2 . ARG A 1 359 ? 31.914 54.861 38.689 1.00 27.63 ? 359 ARG A NH2 1 ATOM 2782 N N . LEU A 1 360 ? 29.049 48.715 32.770 1.00 9.67 ? 360 LEU A N 1 ATOM 2783 C CA . LEU A 1 360 ? 28.085 47.994 31.972 1.00 8.67 ? 360 LEU A CA 1 ATOM 2784 C C . LEU A 1 360 ? 28.633 46.635 31.577 1.00 8.64 ? 360 LEU A C 1 ATOM 2785 O O . LEU A 1 360 ? 27.927 45.609 31.701 1.00 10.82 ? 360 LEU A O 1 ATOM 2786 C CB . LEU A 1 360 ? 27.698 48.810 30.713 1.00 9.71 ? 360 LEU A CB 1 ATOM 2787 C CG . LEU A 1 360 ? 26.853 50.029 31.088 1.00 9.60 ? 360 LEU A CG 1 ATOM 2788 C CD1 . LEU A 1 360 ? 26.953 51.054 29.925 1.00 10.79 ? 360 LEU A CD1 1 ATOM 2789 C CD2 . LEU A 1 360 ? 25.375 49.680 31.208 1.00 11.88 ? 360 LEU A CD2 1 ATOM 2790 N N . PHE A 1 361 ? 29.884 46.545 31.115 1.00 9.68 ? 361 PHE A N 1 ATOM 2791 C CA . PHE A 1 361 ? 30.426 45.247 30.729 1.00 8.69 ? 361 PHE A CA 1 ATOM 2792 C C . PHE A 1 361 ? 30.465 44.277 31.928 1.00 8.89 ? 361 PHE A C 1 ATOM 2793 O O . PHE A 1 361 ? 30.192 43.084 31.776 1.00 10.17 ? 361 PHE A O 1 ATOM 2794 C CB . PHE A 1 361 ? 31.883 45.343 30.200 1.00 8.67 ? 361 PHE A CB 1 ATOM 2795 C CG . PHE A 1 361 ? 32.030 46.189 28.929 1.00 9.84 ? 361 PHE A CG 1 ATOM 2796 C CD1 . PHE A 1 361 ? 30.980 46.402 28.043 1.00 9.51 ? 361 PHE A CD1 1 ATOM 2797 C CD2 . PHE A 1 361 ? 33.270 46.750 28.659 1.00 8.85 ? 361 PHE A CD2 1 ATOM 2798 C CE1 . PHE A 1 361 ? 31.184 47.201 26.863 1.00 10.34 ? 361 PHE A CE1 1 ATOM 2799 C CE2 . PHE A 1 361 ? 33.486 47.545 27.471 1.00 10.00 ? 361 PHE A CE2 1 ATOM 2800 C CZ . PHE A 1 361 ? 32.441 47.749 26.603 1.00 11.25 ? 361 PHE A CZ 1 ATOM 2801 N N . GLU A 1 362 ? 30.894 44.757 33.074 1.00 10.15 ? 362 GLU A N 1 ATOM 2802 C CA . GLU A 1 362 ? 31.030 43.834 34.205 1.00 10.65 ? 362 GLU A CA 1 ATOM 2803 C C . GLU A 1 362 ? 29.661 43.249 34.560 1.00 10.18 ? 362 GLU A C 1 ATOM 2804 O O . GLU A 1 362 ? 29.540 42.032 34.812 1.00 11.54 ? 362 GLU A O 1 ATOM 2805 C CB . GLU A 1 362 ? 31.598 44.529 35.449 1.00 14.71 ? 362 GLU A CB 1 ATOM 2806 C CG . GLU A 1 362 ? 31.708 43.450 36.589 1.00 17.29 ? 362 GLU A CG 1 ATOM 2807 C CD . GLU A 1 362 ? 32.339 43.941 37.880 1.00 24.85 ? 362 GLU A CD 1 ATOM 2808 O OE1 . GLU A 1 362 ? 32.908 45.042 37.859 1.00 24.35 ? 362 GLU A OE1 1 ATOM 2809 O OE2 . GLU A 1 362 ? 32.262 43.204 38.909 1.00 25.21 ? 362 GLU A OE2 1 ATOM 2810 N N . HIS A 1 363 ? 28.631 44.070 34.531 1.00 9.73 ? 363 HIS A N 1 ATOM 2811 C CA . HIS A 1 363 ? 27.282 43.562 34.789 1.00 9.95 ? 363 HIS A CA 1 ATOM 2812 C C . HIS A 1 363 ? 26.804 42.627 33.695 1.00 10.51 ? 363 HIS A C 1 ATOM 2813 O O . HIS A 1 363 ? 26.380 41.485 33.922 1.00 11.90 ? 363 HIS A O 1 ATOM 2814 C CB . HIS A 1 363 ? 26.299 44.715 34.974 1.00 12.29 ? 363 HIS A CB 1 ATOM 2815 C CG . HIS A 1 363 ? 24.887 44.267 35.216 1.00 10.60 ? 363 HIS A CG 1 ATOM 2816 N ND1 . HIS A 1 363 ? 24.453 43.801 36.452 1.00 16.27 ? 363 HIS A ND1 1 ATOM 2817 C CD2 . HIS A 1 363 ? 23.836 44.158 34.377 1.00 13.33 ? 363 HIS A CD2 1 ATOM 2818 C CE1 . HIS A 1 363 ? 23.189 43.418 36.338 1.00 15.11 ? 363 HIS A CE1 1 ATOM 2819 N NE2 . HIS A 1 363 ? 22.788 43.627 35.097 1.00 15.52 ? 363 HIS A NE2 1 ATOM 2820 N N . ILE A 1 364 ? 26.822 43.084 32.443 1.00 10.23 ? 364 ILE A N 1 ATOM 2821 C CA . ILE A 1 364 ? 26.314 42.299 31.351 1.00 10.77 ? 364 ILE A CA 1 ATOM 2822 C C . ILE A 1 364 ? 27.001 40.956 31.206 1.00 9.00 ? 364 ILE A C 1 ATOM 2823 O O . ILE A 1 364 ? 26.329 39.916 31.015 1.00 11.21 ? 364 ILE A O 1 ATOM 2824 C CB . ILE A 1 364 ? 26.441 43.123 30.022 1.00 10.31 ? 364 ILE A CB 1 ATOM 2825 C CG1 . ILE A 1 364 ? 25.453 44.288 30.041 1.00 10.73 ? 364 ILE A CG1 1 ATOM 2826 C CG2 . ILE A 1 364 ? 26.227 42.180 28.828 1.00 11.76 ? 364 ILE A CG2 1 ATOM 2827 C CD1 . ILE A 1 364 ? 25.776 45.379 28.987 1.00 11.38 ? 364 ILE A CD1 1 ATOM 2828 N N . ASN A 1 365 ? 28.305 40.944 31.307 1.00 8.88 ? 365 ASN A N 1 ATOM 2829 C CA . ASN A 1 365 ? 29.067 39.715 31.062 1.00 10.52 ? 365 ASN A CA 1 ATOM 2830 C C . ASN A 1 365 ? 28.860 38.706 32.192 1.00 13.78 ? 365 ASN A C 1 ATOM 2831 O O . ASN A 1 365 ? 29.144 37.516 31.993 1.00 15.63 ? 365 ASN A O 1 ATOM 2832 C CB . ASN A 1 365 ? 30.557 40.000 30.868 1.00 10.73 ? 365 ASN A CB 1 ATOM 2833 C CG . ASN A 1 365 ? 30.822 40.870 29.629 1.00 9.43 ? 365 ASN A CG 1 ATOM 2834 O OD1 . ASN A 1 365 ? 29.908 41.086 28.793 1.00 11.05 ? 365 ASN A OD1 1 ATOM 2835 N ND2 . ASN A 1 365 ? 32.042 41.344 29.517 1.00 9.48 ? 365 ASN A ND2 1 ATOM 2836 N N . SER A 1 366 ? 28.367 39.143 33.338 1.00 13.30 ? 366 SER A N 1 ATOM 2837 C CA . SER A 1 366 ? 28.118 38.225 34.454 1.00 14.76 ? 366 SER A CA 1 ATOM 2838 C C . SER A 1 366 ? 26.665 37.802 34.583 1.00 17.40 ? 366 SER A C 1 ATOM 2839 O O . SER A 1 366 ? 26.354 36.979 35.442 1.00 21.15 ? 366 SER A O 1 ATOM 2840 C CB . SER A 1 366 ? 28.630 38.806 35.768 1.00 19.33 ? 366 SER A CB 1 ATOM 2841 O OG . SER A 1 366 ? 27.883 39.931 36.133 1.00 19.64 ? 366 SER A OG 1 ATOM 2842 N N . GLN A 1 367 ? 25.782 38.346 33.757 1.00 17.66 ? 367 GLN A N 1 ATOM 2843 C CA . GLN A 1 367 ? 24.360 37.994 33.831 1.00 18.19 ? 367 GLN A CA 1 ATOM 2844 C C . GLN A 1 367 ? 24.122 36.981 32.728 1.00 17.82 ? 367 GLN A C 1 ATOM 2845 O O . GLN A 1 367 ? 23.937 37.311 31.549 1.00 16.78 ? 367 GLN A O 1 ATOM 2846 C CB . GLN A 1 367 ? 23.485 39.237 33.607 1.00 18.97 ? 367 GLN A CB 1 ATOM 2847 C CG . GLN A 1 367 ? 23.487 40.178 34.836 1.00 25.46 ? 367 GLN A CG 1 ATOM 2848 C CD . GLN A 1 367 ? 22.876 39.493 36.058 1.00 28.54 ? 367 GLN A CD 1 ATOM 2849 O OE1 . GLN A 1 367 ? 21.715 39.142 36.046 1.00 32.84 ? 367 GLN A OE1 1 ATOM 2850 N NE2 . GLN A 1 367 ? 23.669 39.280 37.091 1.00 35.51 ? 367 GLN A NE2 1 ATOM 2851 N N . ALA A 1 368 ? 24.149 35.700 33.076 1.00 18.75 ? 368 ALA A N 1 ATOM 2852 C CA . ALA A 1 368 ? 23.977 34.661 32.052 1.00 17.83 ? 368 ALA A CA 1 ATOM 2853 C C . ALA A 1 368 ? 22.788 34.861 31.127 1.00 17.90 ? 368 ALA A C 1 ATOM 2854 O O . ALA A 1 368 ? 22.912 34.569 29.921 1.00 18.72 ? 368 ALA A O 1 ATOM 2855 C CB . ALA A 1 368 ? 23.861 33.268 32.737 1.00 19.70 ? 368 ALA A CB 1 ATOM 2856 N N . HIS A 1 369 ? 21.656 35.316 31.659 1.00 16.47 ? 369 HIS A N 1 ATOM 2857 C CA . HIS A 1 369 ? 20.469 35.505 30.851 1.00 15.90 ? 369 HIS A CA 1 ATOM 2858 C C . HIS A 1 369 ? 20.621 36.379 29.608 1.00 16.26 ? 369 HIS A C 1 ATOM 2859 O O . HIS A 1 369 ? 19.844 36.271 28.689 1.00 18.09 ? 369 HIS A O 1 ATOM 2860 C CB . HIS A 1 369 ? 19.273 35.973 31.689 1.00 21.05 ? 369 HIS A CB 1 ATOM 2861 C CG . HIS A 1 369 ? 19.353 37.400 32.123 1.00 24.41 ? 369 HIS A CG 1 ATOM 2862 N ND1 . HIS A 1 369 ? 19.948 37.779 33.300 1.00 28.53 ? 369 HIS A ND1 1 ATOM 2863 C CD2 . HIS A 1 369 ? 18.909 38.538 31.543 1.00 25.66 ? 369 HIS A CD2 1 ATOM 2864 C CE1 . HIS A 1 369 ? 19.879 39.091 33.425 1.00 25.52 ? 369 HIS A CE1 1 ATOM 2865 N NE2 . HIS A 1 369 ? 19.248 39.572 32.373 1.00 28.83 ? 369 HIS A NE2 1 ATOM 2866 N N . PHE A 1 370 ? 21.589 37.284 29.588 1.00 17.09 ? 370 PHE A N 1 ATOM 2867 C CA . PHE A 1 370 ? 21.839 38.086 28.384 1.00 15.17 ? 370 PHE A CA 1 ATOM 2868 C C . PHE A 1 370 ? 22.534 37.288 27.297 1.00 13.59 ? 370 PHE A C 1 ATOM 2869 O O . PHE A 1 370 ? 22.356 37.583 26.140 1.00 13.37 ? 370 PHE A O 1 ATOM 2870 C CB . PHE A 1 370 ? 22.715 39.295 28.698 1.00 14.74 ? 370 PHE A CB 1 ATOM 2871 C CG . PHE A 1 370 ? 22.016 40.405 29.433 1.00 15.51 ? 370 PHE A CG 1 ATOM 2872 C CD1 . PHE A 1 370 ? 20.819 40.932 28.992 1.00 16.61 ? 370 PHE A CD1 1 ATOM 2873 C CD2 . PHE A 1 370 ? 22.596 40.954 30.542 1.00 14.01 ? 370 PHE A CD2 1 ATOM 2874 C CE1 . PHE A 1 370 ? 20.230 41.968 29.673 1.00 18.79 ? 370 PHE A CE1 1 ATOM 2875 C CE2 . PHE A 1 370 ? 22.000 41.982 31.218 1.00 18.02 ? 370 PHE A CE2 1 ATOM 2876 C CZ . PHE A 1 370 ? 20.832 42.492 30.771 1.00 18.26 ? 370 PHE A CZ 1 ATOM 2877 N N . ASN A 1 371 ? 23.370 36.326 27.689 1.00 12.47 ? 371 ASN A N 1 ATOM 2878 C CA . ASN A 1 371 ? 24.185 35.542 26.780 1.00 12.05 ? 371 ASN A CA 1 ATOM 2879 C C . ASN A 1 371 ? 25.010 36.455 25.866 1.00 11.23 ? 371 ASN A C 1 ATOM 2880 O O . ASN A 1 371 ? 25.061 36.242 24.641 1.00 12.46 ? 371 ASN A O 1 ATOM 2881 C CB . ASN A 1 371 ? 23.317 34.576 25.963 1.00 13.89 ? 371 ASN A CB 1 ATOM 2882 C CG . ASN A 1 371 ? 22.638 33.528 26.876 1.00 14.72 ? 371 ASN A CG 1 ATOM 2883 O OD1 . ASN A 1 371 ? 23.320 32.688 27.456 1.00 18.40 ? 371 ASN A OD1 1 ATOM 2884 N ND2 . ASN A 1 371 ? 21.327 33.658 27.033 1.00 17.21 ? 371 ASN A ND2 1 ATOM 2885 N N . VAL A 1 372 ? 25.625 37.450 26.488 1.00 10.32 ? 372 VAL A N 1 ATOM 2886 C CA . VAL A 1 372 ? 26.491 38.424 25.764 1.00 10.41 ? 372 VAL A CA 1 ATOM 2887 C C . VAL A 1 372 ? 27.847 38.493 26.412 1.00 9.85 ? 372 VAL A C 1 ATOM 2888 O O . VAL A 1 372 ? 28.003 38.370 27.666 1.00 11.49 ? 372 VAL A O 1 ATOM 2889 C CB . VAL A 1 372 ? 25.880 39.831 25.872 1.00 11.29 ? 372 VAL A CB 1 ATOM 2890 C CG1 . VAL A 1 372 ? 26.890 40.934 25.381 1.00 10.76 ? 372 VAL A CG1 1 ATOM 2891 C CG2 . VAL A 1 372 ? 24.613 39.923 25.018 1.00 12.88 ? 372 VAL A CG2 1 ATOM 2892 N N . GLN A 1 373 ? 28.896 38.616 25.602 1.00 9.71 ? 373 GLN A N 1 ATOM 2893 C CA . GLN A 1 373 ? 30.248 38.876 26.100 1.00 9.42 ? 373 GLN A CA 1 ATOM 2894 C C . GLN A 1 373 ? 30.677 40.206 25.383 1.00 9.12 ? 373 GLN A C 1 ATOM 2895 O O . GLN A 1 373 ? 30.939 40.189 24.146 1.00 10.27 ? 373 GLN A O 1 ATOM 2896 C CB . GLN A 1 373 ? 31.196 37.709 25.780 1.00 10.57 ? 373 GLN A CB 1 ATOM 2897 C CG . GLN A 1 373 ? 32.664 38.020 26.098 1.00 11.94 ? 373 GLN A CG 1 ATOM 2898 C CD . GLN A 1 373 ? 32.899 38.400 27.600 1.00 15.33 ? 373 GLN A CD 1 ATOM 2899 O OE1 . GLN A 1 373 ? 32.189 37.909 28.489 1.00 16.24 ? 373 GLN A OE1 1 ATOM 2900 N NE2 . GLN A 1 373 ? 33.887 39.206 27.867 1.00 15.05 ? 373 GLN A NE2 1 ATOM 2901 N N . ALA A 1 374 ? 30.750 41.307 26.107 1.00 8.18 ? 374 ALA A N 1 ATOM 2902 C CA . ALA A 1 374 ? 31.053 42.620 25.521 1.00 9.25 ? 374 ALA A CA 1 ATOM 2903 C C . ALA A 1 374 ? 32.384 43.121 26.000 1.00 9.55 ? 374 ALA A C 1 ATOM 2904 O O . ALA A 1 374 ? 32.753 42.952 27.192 1.00 9.52 ? 374 ALA A O 1 ATOM 2905 C CB . ALA A 1 374 ? 29.975 43.558 25.913 1.00 10.08 ? 374 ALA A CB 1 ATOM 2906 N N . GLN A 1 375 ? 33.111 43.813 25.135 1.00 8.79 ? 375 GLN A N 1 ATOM 2907 C CA . GLN A 1 375 ? 34.424 44.359 25.506 1.00 9.04 ? 375 GLN A CA 1 ATOM 2908 C C . GLN A 1 375 ? 34.839 45.454 24.546 1.00 8.51 ? 375 GLN A C 1 ATOM 2909 O O . GLN A 1 375 ? 34.259 45.570 23.453 1.00 9.42 ? 375 GLN A O 1 ATOM 2910 C CB . GLN A 1 375 ? 35.513 43.291 25.430 1.00 12.17 ? 375 GLN A CB 1 ATOM 2911 C CG . GLN A 1 375 ? 35.519 42.496 24.108 1.00 13.58 ? 375 GLN A CG 1 ATOM 2912 C CD . GLN A 1 375 ? 34.667 41.208 24.221 1.00 22.82 ? 375 GLN A CD 1 ATOM 2913 O OE1 . GLN A 1 375 ? 34.937 40.363 25.116 1.00 21.01 ? 375 GLN A OE1 1 ATOM 2914 N NE2 . GLN A 1 375 ? 33.637 41.035 23.345 1.00 17.39 ? 375 GLN A NE2 1 ATOM 2915 N N . PHE A 1 376 ? 35.771 46.288 24.976 1.00 8.13 ? 376 PHE A N 1 ATOM 2916 C CA . PHE A 1 376 ? 36.381 47.229 24.006 1.00 8.14 ? 376 PHE A CA 1 ATOM 2917 C C . PHE A 1 376 ? 37.146 46.388 23.000 1.00 10.41 ? 376 PHE A C 1 ATOM 2918 O O . PHE A 1 376 ? 37.814 45.388 23.339 1.00 11.46 ? 376 PHE A O 1 ATOM 2919 C CB . PHE A 1 376 ? 37.357 48.173 24.711 1.00 8.77 ? 376 PHE A CB 1 ATOM 2920 C CG . PHE A 1 376 ? 36.687 49.111 25.634 1.00 9.60 ? 376 PHE A CG 1 ATOM 2921 C CD1 . PHE A 1 376 ? 35.680 49.944 25.200 1.00 9.83 ? 376 PHE A CD1 1 ATOM 2922 C CD2 . PHE A 1 376 ? 37.066 49.135 26.991 1.00 10.38 ? 376 PHE A CD2 1 ATOM 2923 C CE1 . PHE A 1 376 ? 35.050 50.809 26.149 1.00 11.89 ? 376 PHE A CE1 1 ATOM 2924 C CE2 . PHE A 1 376 ? 36.444 49.990 27.884 1.00 12.60 ? 376 PHE A CE2 1 ATOM 2925 C CZ . PHE A 1 376 ? 35.468 50.802 27.482 1.00 11.61 ? 376 PHE A CZ 1 ATOM 2926 N N . GLY A 1 377 ? 37.153 46.856 21.753 1.00 8.98 ? 377 GLY A N 1 ATOM 2927 C CA . GLY A 1 377 ? 37.902 46.143 20.720 1.00 8.83 ? 377 GLY A CA 1 ATOM 2928 C C . GLY A 1 377 ? 38.385 47.119 19.664 1.00 8.41 ? 377 GLY A C 1 ATOM 2929 O O . GLY A 1 377 ? 38.083 48.295 19.710 1.00 9.20 ? 377 GLY A O 1 ATOM 2930 N N . THR A 1 378 ? 39.176 46.571 18.721 1.00 10.22 ? 378 THR A N 1 ATOM 2931 C CA . THR A 1 378 ? 39.612 47.330 17.561 1.00 10.84 ? 378 THR A CA 1 ATOM 2932 C C . THR A 1 378 ? 38.835 46.795 16.358 1.00 9.38 ? 378 THR A C 1 ATOM 2933 O O . THR A 1 378 ? 38.108 45.790 16.392 1.00 9.93 ? 378 THR A O 1 ATOM 2934 C CB . THR A 1 378 ? 41.102 47.222 17.290 1.00 11.71 ? 378 THR A CB 1 ATOM 2935 O OG1 . THR A 1 378 ? 41.404 45.877 16.889 1.00 11.56 ? 378 THR A OG1 1 ATOM 2936 C CG2 . THR A 1 378 ? 41.930 47.644 18.518 1.00 12.22 ? 378 THR A CG2 1 ATOM 2937 N N . LEU A 1 379 ? 38.972 47.539 15.252 1.00 9.53 ? 379 LEU A N 1 ATOM 2938 C CA . LEU A 1 379 ? 38.293 47.134 14.020 1.00 8.52 ? 379 LEU A CA 1 ATOM 2939 C C . LEU A 1 379 ? 38.778 45.770 13.480 1.00 7.79 ? 379 LEU A C 1 ATOM 2940 O O . LEU A 1 379 ? 37.988 44.922 13.062 1.00 8.47 ? 379 LEU A O 1 ATOM 2941 C CB . LEU A 1 379 ? 38.458 48.260 12.970 1.00 8.05 ? 379 LEU A CB 1 ATOM 2942 C CG . LEU A 1 379 ? 37.690 48.015 11.658 1.00 7.79 ? 379 LEU A CG 1 ATOM 2943 C CD1 . LEU A 1 379 ? 36.199 48.026 11.927 1.00 10.26 ? 379 LEU A CD1 1 ATOM 2944 C CD2 . LEU A 1 379 ? 38.065 49.110 10.619 1.00 10.45 ? 379 LEU A CD2 1 ATOM 2945 N N . GLN A 1 380 ? 40.101 45.559 13.497 1.00 8.17 ? 380 GLN A N 1 ATOM 2946 C CA . GLN A 1 380 ? 40.625 44.273 13.040 1.00 9.09 ? 380 GLN A CA 1 ATOM 2947 C C . GLN A 1 380 ? 40.135 43.140 13.933 1.00 10.12 ? 380 GLN A C 1 ATOM 2948 O O . GLN A 1 380 ? 39.884 42.029 13.425 1.00 9.53 ? 380 GLN A O 1 ATOM 2949 C CB . GLN A 1 380 ? 42.163 44.311 12.993 1.00 10.13 ? 380 GLN A CB 1 ATOM 2950 C CG . GLN A 1 380 ? 42.815 43.027 12.455 1.00 14.35 ? 380 GLN A CG 1 ATOM 2951 C CD . GLN A 1 380 ? 42.456 42.853 11.022 1.00 16.37 ? 380 GLN A CD 1 ATOM 2952 O OE1 . GLN A 1 380 ? 42.580 43.810 10.241 1.00 17.35 ? 380 GLN A OE1 1 ATOM 2953 N NE2 . GLN A 1 380 ? 41.971 41.643 10.637 1.00 19.73 ? 380 GLN A NE2 1 ATOM 2954 N N . GLU A 1 381 ? 39.998 43.376 15.239 1.00 8.90 ? 381 GLU A N 1 ATOM 2955 C CA . GLU A 1 381 ? 39.496 42.318 16.115 1.00 9.67 ? 381 GLU A CA 1 ATOM 2956 C C . GLU A 1 381 ? 38.070 41.917 15.707 1.00 8.09 ? 381 GLU A C 1 ATOM 2957 O O . GLU A 1 381 ? 37.723 40.735 15.734 1.00 11.26 ? 381 GLU A O 1 ATOM 2958 C CB . GLU A 1 381 ? 39.430 42.807 17.552 1.00 11.77 ? 381 GLU A CB 1 ATOM 2959 C CG . GLU A 1 381 ? 40.692 42.774 18.371 1.00 17.80 ? 381 GLU A CG 1 ATOM 2960 C CD . GLU A 1 381 ? 40.312 43.090 19.811 1.00 21.22 ? 381 GLU A CD 1 ATOM 2961 O OE1 . GLU A 1 381 ? 39.955 42.175 20.608 1.00 27.32 ? 381 GLU A OE1 1 ATOM 2962 O OE2 . GLU A 1 381 ? 40.329 44.258 20.131 1.00 19.37 ? 381 GLU A OE2 1 ATOM 2963 N N . TYR A 1 382 ? 37.248 42.902 15.366 1.00 8.56 ? 382 TYR A N 1 ATOM 2964 C CA . TYR A 1 382 ? 35.908 42.600 14.916 1.00 7.97 ? 382 TYR A CA 1 ATOM 2965 C C . TYR A 1 382 ? 35.960 41.707 13.643 1.00 8.62 ? 382 TYR A C 1 ATOM 2966 O O . TYR A 1 382 ? 35.324 40.663 13.566 1.00 8.57 ? 382 TYR A O 1 ATOM 2967 C CB . TYR A 1 382 ? 35.137 43.898 14.587 1.00 8.74 ? 382 TYR A CB 1 ATOM 2968 C CG . TYR A 1 382 ? 33.842 43.646 13.883 1.00 7.47 ? 382 TYR A CG 1 ATOM 2969 C CD1 . TYR A 1 382 ? 32.764 43.062 14.540 1.00 8.21 ? 382 TYR A CD1 1 ATOM 2970 C CD2 . TYR A 1 382 ? 33.726 43.887 12.503 1.00 8.44 ? 382 TYR A CD2 1 ATOM 2971 C CE1 . TYR A 1 382 ? 31.591 42.715 13.865 1.00 9.22 ? 382 TYR A CE1 1 ATOM 2972 C CE2 . TYR A 1 382 ? 32.559 43.555 11.813 1.00 9.96 ? 382 TYR A CE2 1 ATOM 2973 C CZ . TYR A 1 382 ? 31.496 42.960 12.513 1.00 8.33 ? 382 TYR A CZ 1 ATOM 2974 O OH . TYR A 1 382 ? 30.293 42.626 11.897 1.00 10.18 ? 382 TYR A OH 1 ATOM 2975 N N . PHE A 1 383 ? 36.714 42.149 12.644 1.00 7.69 ? 383 PHE A N 1 ATOM 2976 C CA . PHE A 1 383 ? 36.734 41.366 11.389 1.00 8.16 ? 383 PHE A CA 1 ATOM 2977 C C . PHE A 1 383 ? 37.335 39.973 11.598 1.00 8.76 ? 383 PHE A C 1 ATOM 2978 O O . PHE A 1 383 ? 36.854 39.018 10.972 1.00 9.51 ? 383 PHE A O 1 ATOM 2979 C CB . PHE A 1 383 ? 37.498 42.141 10.296 1.00 8.20 ? 383 PHE A CB 1 ATOM 2980 C CG . PHE A 1 383 ? 36.719 43.310 9.701 1.00 8.10 ? 383 PHE A CG 1 ATOM 2981 C CD1 . PHE A 1 383 ? 35.520 43.107 9.034 1.00 8.89 ? 383 PHE A CD1 1 ATOM 2982 C CD2 . PHE A 1 383 ? 37.237 44.608 9.776 1.00 7.80 ? 383 PHE A CD2 1 ATOM 2983 C CE1 . PHE A 1 383 ? 34.792 44.195 8.432 1.00 9.30 ? 383 PHE A CE1 1 ATOM 2984 C CE2 . PHE A 1 383 ? 36.508 45.674 9.170 1.00 8.77 ? 383 PHE A CE2 1 ATOM 2985 C CZ . PHE A 1 383 ? 35.337 45.484 8.526 1.00 9.51 ? 383 PHE A CZ 1 ATOM 2986 N N . ASP A 1 384 ? 38.401 39.901 12.392 1.00 9.25 ? 384 ASP A N 1 ATOM 2987 C CA . ASP A 1 384 ? 38.957 38.561 12.647 1.00 10.29 ? 384 ASP A CA 1 ATOM 2988 C C . ASP A 1 384 ? 37.892 37.625 13.252 1.00 9.91 ? 384 ASP A C 1 ATOM 2989 O O . ASP A 1 384 ? 37.772 36.439 12.824 1.00 10.37 ? 384 ASP A O 1 ATOM 2990 C CB . ASP A 1 384 ? 40.141 38.649 13.617 1.00 12.64 ? 384 ASP A CB 1 ATOM 2991 C CG . ASP A 1 384 ? 41.368 39.258 12.990 1.00 14.69 ? 384 ASP A CG 1 ATOM 2992 O OD1 . ASP A 1 384 ? 41.447 39.411 11.759 1.00 17.50 ? 384 ASP A OD1 1 ATOM 2993 O OD2 . ASP A 1 384 ? 42.279 39.575 13.778 1.00 20.41 ? 384 ASP A OD2 1 ATOM 2994 N N . ALA A 1 385 ? 37.094 38.120 14.193 1.00 9.69 ? 385 ALA A N 1 ATOM 2995 C CA . ALA A 1 385 ? 36.055 37.254 14.787 1.00 9.49 ? 385 ALA A CA 1 ATOM 2996 C C . ALA A 1 385 ? 34.953 36.925 13.786 1.00 10.91 ? 385 ALA A C 1 ATOM 2997 O O . ALA A 1 385 ? 34.449 35.776 13.772 1.00 10.82 ? 385 ALA A O 1 ATOM 2998 C CB . ALA A 1 385 ? 35.514 37.937 16.035 1.00 9.93 ? 385 ALA A CB 1 ATOM 2999 N N . VAL A 1 386 ? 34.543 37.891 12.939 1.00 9.85 ? 386 VAL A N 1 ATOM 3000 C CA . VAL A 1 386 ? 33.564 37.580 11.911 1.00 10.52 ? 386 VAL A CA 1 ATOM 3001 C C . VAL A 1 386 ? 34.055 36.457 10.990 1.00 10.98 ? 386 VAL A C 1 ATOM 3002 O O . VAL A 1 386 ? 33.270 35.508 10.679 1.00 11.21 ? 386 VAL A O 1 ATOM 3003 C CB . VAL A 1 386 ? 33.278 38.842 11.044 1.00 10.20 ? 386 VAL A CB 1 ATOM 3004 C CG1 . VAL A 1 386 ? 32.469 38.503 9.767 1.00 12.95 ? 386 VAL A CG1 1 ATOM 3005 C CG2 . VAL A 1 386 ? 32.546 39.877 11.857 1.00 11.31 ? 386 VAL A CG2 1 ATOM 3006 N N . HIS A 1 387 ? 35.308 36.517 10.552 1.00 10.99 ? 387 HIS A N 1 ATOM 3007 C CA . HIS A 1 387 ? 35.804 35.477 9.650 1.00 11.17 ? 387 HIS A CA 1 ATOM 3008 C C . HIS A 1 387 ? 36.026 34.133 10.377 1.00 11.81 ? 387 HIS A C 1 ATOM 3009 O O . HIS A 1 387 ? 35.934 33.081 9.707 1.00 11.63 ? 387 HIS A O 1 ATOM 3010 C CB . HIS A 1 387 ? 37.040 35.950 8.897 1.00 11.33 ? 387 HIS A CB 1 ATOM 3011 C CG . HIS A 1 387 ? 36.727 37.083 7.959 1.00 9.61 ? 387 HIS A CG 1 ATOM 3012 N ND1 . HIS A 1 387 ? 35.814 36.960 6.926 1.00 13.41 ? 387 HIS A ND1 1 ATOM 3013 C CD2 . HIS A 1 387 ? 37.166 38.368 7.939 1.00 10.17 ? 387 HIS A CD2 1 ATOM 3014 C CE1 . HIS A 1 387 ? 35.723 38.132 6.295 1.00 13.58 ? 387 HIS A CE1 1 ATOM 3015 N NE2 . HIS A 1 387 ? 36.528 38.992 6.892 1.00 12.92 ? 387 HIS A NE2 1 ATOM 3016 N N . GLN A 1 388 ? 36.308 34.162 11.665 1.00 12.30 ? 388 GLN A N 1 ATOM 3017 C CA . GLN A 1 388 ? 36.360 32.921 12.436 1.00 12.90 ? 388 GLN A CA 1 ATOM 3018 C C . GLN A 1 388 ? 34.988 32.237 12.397 1.00 14.95 ? 388 GLN A C 1 ATOM 3019 O O . GLN A 1 388 ? 34.874 31.045 12.195 1.00 16.07 ? 388 GLN A O 1 ATOM 3020 C CB . GLN A 1 388 ? 36.805 33.234 13.857 1.00 14.56 ? 388 GLN A CB 1 ATOM 3021 C CG . GLN A 1 388 ? 38.313 33.477 13.961 1.00 21.72 ? 388 GLN A CG 1 ATOM 3022 C CD . GLN A 1 388 ? 38.709 34.241 15.224 1.00 30.75 ? 388 GLN A CD 1 ATOM 3023 O OE1 . GLN A 1 388 ? 37.936 34.342 16.172 1.00 34.00 ? 388 GLN A OE1 1 ATOM 3024 N NE2 . GLN A 1 388 ? 39.913 34.776 15.235 1.00 31.61 ? 388 GLN A NE2 1 ATOM 3025 N N . ALA A 1 389 ? 33.947 33.014 12.551 1.00 12.27 ? 389 ALA A N 1 ATOM 3026 C CA . ALA A 1 389 ? 32.564 32.489 12.519 1.00 14.44 ? 389 ALA A CA 1 ATOM 3027 C C . ALA A 1 389 ? 32.281 31.950 11.121 1.00 16.64 ? 389 ALA A C 1 ATOM 3028 O O . ALA A 1 389 ? 31.726 30.852 10.960 1.00 18.08 ? 389 ALA A O 1 ATOM 3029 C CB . ALA A 1 389 ? 31.586 33.562 12.890 1.00 14.41 ? 389 ALA A CB 1 ATOM 3030 N N . GLU A 1 390 ? 32.684 32.692 10.078 1.00 15.06 ? 390 GLU A N 1 ATOM 3031 C CA . GLU A 1 390 ? 32.488 32.252 8.686 1.00 15.01 ? 390 GLU A CA 1 ATOM 3032 C C . GLU A 1 390 ? 33.175 30.917 8.435 1.00 17.71 ? 390 GLU A C 1 ATOM 3033 O O . GLU A 1 390 ? 32.568 29.994 7.846 1.00 20.54 ? 390 GLU A O 1 ATOM 3034 C CB . GLU A 1 390 ? 33.079 33.323 7.735 1.00 14.97 ? 390 GLU A CB 1 ATOM 3035 C CG . GLU A 1 390 ? 32.867 33.038 6.245 1.00 17.78 ? 390 GLU A CG 1 ATOM 3036 C CD . GLU A 1 390 ? 33.616 34.054 5.399 1.00 21.13 ? 390 GLU A CD 1 ATOM 3037 O OE1 . GLU A 1 390 ? 34.486 34.764 5.963 1.00 21.71 ? 390 GLU A OE1 1 ATOM 3038 O OE2 . GLU A 1 390 ? 33.362 34.155 4.184 1.00 21.58 ? 390 GLU A OE2 1 ATOM 3039 N N . ARG A 1 391 ? 34.436 30.797 8.854 1.00 16.89 ? 391 ARG A N 1 ATOM 3040 C CA . ARG A 1 391 ? 35.177 29.549 8.633 1.00 20.28 ? 391 ARG A CA 1 ATOM 3041 C C . ARG A 1 391 ? 34.565 28.394 9.434 1.00 21.36 ? 391 ARG A C 1 ATOM 3042 O O . ARG A 1 391 ? 34.682 27.210 9.017 1.00 26.05 ? 391 ARG A O 1 ATOM 3043 C CB . ARG A 1 391 ? 36.647 29.745 9.017 1.00 22.31 ? 391 ARG A CB 1 ATOM 3044 C CG . ARG A 1 391 ? 37.426 30.657 8.069 1.00 28.52 ? 391 ARG A CG 1 ATOM 3045 C CD . ARG A 1 391 ? 38.922 30.498 8.308 1.00 30.52 ? 391 ARG A CD 1 ATOM 3046 N NE . ARG A 1 391 ? 39.353 30.997 9.611 1.00 32.59 ? 391 ARG A NE 1 ATOM 3047 C CZ . ARG A 1 391 ? 39.530 32.291 9.891 1.00 28.15 ? 391 ARG A CZ 1 ATOM 3048 N NH1 . ARG A 1 391 ? 39.317 33.211 8.955 1.00 29.66 ? 391 ARG A NH1 1 ATOM 3049 N NH2 . ARG A 1 391 ? 39.912 32.645 11.101 1.00 32.73 ? 391 ARG A NH2 1 ATOM 3050 N N . ALA A 1 392 ? 33.902 28.690 10.538 1.00 19.61 ? 392 ALA A N 1 ATOM 3051 C CA . ALA A 1 392 ? 33.267 27.613 11.320 1.00 22.19 ? 392 ALA A CA 1 ATOM 3052 C C . ALA A 1 392 ? 31.917 27.229 10.657 1.00 24.72 ? 392 ALA A C 1 ATOM 3053 O O . ALA A 1 392 ? 31.146 26.415 11.212 1.00 27.28 ? 392 ALA A O 1 ATOM 3054 C CB . ALA A 1 392 ? 33.041 28.058 12.741 1.00 20.69 ? 392 ALA A CB 1 ATOM 3055 N N . GLY A 1 393 ? 31.606 27.817 9.493 1.00 22.33 ? 393 GLY A N 1 ATOM 3056 C CA . GLY A 1 393 ? 30.360 27.470 8.827 1.00 23.72 ? 393 GLY A CA 1 ATOM 3057 C C . GLY A 1 393 ? 29.130 28.109 9.421 1.00 18.56 ? 393 GLY A C 1 ATOM 3058 O O . GLY A 1 393 ? 27.995 27.729 9.107 1.00 22.74 ? 393 GLY A O 1 ATOM 3059 N N . GLN A 1 394 ? 29.347 29.152 10.204 1.00 19.23 ? 394 GLN A N 1 ATOM 3060 C CA . GLN A 1 394 ? 28.269 29.854 10.873 1.00 20.99 ? 394 GLN A CA 1 ATOM 3061 C C . GLN A 1 394 ? 27.509 30.874 10.003 1.00 17.77 ? 394 GLN A C 1 ATOM 3062 O O . GLN A 1 394 ? 26.444 31.285 10.355 1.00 22.73 ? 394 GLN A O 1 ATOM 3063 C CB . GLN A 1 394 ? 28.839 30.538 12.125 1.00 24.63 ? 394 GLN A CB 1 ATOM 3064 C CG . GLN A 1 394 ? 27.850 30.957 13.157 1.00 34.84 ? 394 GLN A CG 1 ATOM 3065 C CD . GLN A 1 394 ? 28.338 32.087 14.025 1.00 33.62 ? 394 GLN A CD 1 ATOM 3066 O OE1 . GLN A 1 394 ? 28.005 33.247 13.801 1.00 36.02 ? 394 GLN A OE1 1 ATOM 3067 N NE2 . GLN A 1 394 ? 29.111 31.748 15.042 1.00 18.21 ? 394 GLN A NE2 1 ATOM 3068 N N . ALA A 1 395 ? 28.076 31.279 8.873 1.00 17.93 ? 395 ALA A N 1 ATOM 3069 C CA . ALA A 1 395 ? 27.499 32.298 8.008 1.00 16.54 ? 395 ALA A CA 1 ATOM 3070 C C . ALA A 1 395 ? 28.193 32.248 6.631 1.00 14.79 ? 395 ALA A C 1 ATOM 3071 O O . ALA A 1 395 ? 29.334 31.823 6.518 1.00 17.67 ? 395 ALA A O 1 ATOM 3072 C CB . ALA A 1 395 ? 27.718 33.695 8.670 1.00 20.96 ? 395 ALA A CB 1 ATOM 3073 N N . GLU A 1 396 ? 27.472 32.645 5.578 1.00 16.85 ? 396 GLU A N 1 ATOM 3074 C CA . GLU A 1 396 ? 28.051 32.762 4.224 1.00 15.21 ? 396 GLU A CA 1 ATOM 3075 C C . GLU A 1 396 ? 27.588 34.161 3.801 1.00 14.49 ? 396 GLU A C 1 ATOM 3076 O O . GLU A 1 396 ? 26.494 34.604 4.197 1.00 17.46 ? 396 GLU A O 1 ATOM 3077 C CB . GLU A 1 396 ? 27.499 31.685 3.290 1.00 22.24 ? 396 GLU A CB 1 ATOM 3078 C CG . GLU A 1 396 ? 26.006 31.697 3.143 1.00 30.83 ? 396 GLU A CG 1 ATOM 3079 C CD . GLU A 1 396 ? 25.521 30.546 2.274 1.00 38.98 ? 396 GLU A CD 1 ATOM 3080 O OE1 . GLU A 1 396 ? 26.361 29.680 1.924 1.00 39.93 ? 396 GLU A OE1 1 ATOM 3081 O OE2 . GLU A 1 396 ? 24.312 30.510 1.944 1.00 44.58 ? 396 GLU A OE2 1 ATOM 3082 N N . PHE A 1 397 ? 28.431 34.824 3.021 1.00 12.81 ? 397 PHE A N 1 ATOM 3083 C CA . PHE A 1 397 ? 28.137 36.194 2.664 1.00 9.68 ? 397 PHE A CA 1 ATOM 3084 C C . PHE A 1 397 ? 27.829 36.355 1.195 1.00 9.78 ? 397 PHE A C 1 ATOM 3085 O O . PHE A 1 397 ? 28.387 35.661 0.360 1.00 12.84 ? 397 PHE A O 1 ATOM 3086 C CB . PHE A 1 397 ? 29.352 37.059 3.029 1.00 11.53 ? 397 PHE A CB 1 ATOM 3087 C CG . PHE A 1 397 ? 29.662 37.081 4.517 1.00 11.98 ? 397 PHE A CG 1 ATOM 3088 C CD1 . PHE A 1 397 ? 28.824 37.746 5.381 1.00 9.35 ? 397 PHE A CD1 1 ATOM 3089 C CD2 . PHE A 1 397 ? 30.756 36.397 5.018 1.00 13.31 ? 397 PHE A CD2 1 ATOM 3090 C CE1 . PHE A 1 397 ? 29.057 37.719 6.748 1.00 11.33 ? 397 PHE A CE1 1 ATOM 3091 C CE2 . PHE A 1 397 ? 30.989 36.366 6.429 1.00 12.89 ? 397 PHE A CE2 1 ATOM 3092 C CZ . PHE A 1 397 ? 30.146 37.015 7.235 1.00 10.76 ? 397 PHE A CZ 1 ATOM 3093 N N . PRO A 1 398 ? 26.940 37.258 0.902 1.00 8.97 ? 398 PRO A N 1 ATOM 3094 C CA . PRO A 1 398 ? 26.564 37.533 -0.473 1.00 9.07 ? 398 PRO A CA 1 ATOM 3095 C C . PRO A 1 398 ? 27.631 38.290 -1.227 1.00 9.39 ? 398 PRO A C 1 ATOM 3096 O O . PRO A 1 398 ? 28.469 38.988 -0.612 1.00 10.25 ? 398 PRO A O 1 ATOM 3097 C CB . PRO A 1 398 ? 25.327 38.365 -0.305 1.00 11.53 ? 398 PRO A CB 1 ATOM 3098 C CG . PRO A 1 398 ? 25.558 39.168 0.962 1.00 11.87 ? 398 PRO A CG 1 ATOM 3099 C CD . PRO A 1 398 ? 26.217 38.110 1.842 1.00 10.50 ? 398 PRO A CD 1 ATOM 3100 N N . THR A 1 399 ? 27.607 38.150 -2.532 1.00 8.92 ? 399 THR A N 1 ATOM 3101 C CA . THR A 1 399 ? 28.523 38.891 -3.427 1.00 8.10 ? 399 THR A CA 1 ATOM 3102 C C . THR A 1 399 ? 27.743 40.109 -3.939 1.00 8.45 ? 399 THR A C 1 ATOM 3103 O O . THR A 1 399 ? 26.532 40.096 -4.106 1.00 9.03 ? 399 THR A O 1 ATOM 3104 C CB . THR A 1 399 ? 28.937 38.009 -4.565 1.00 9.29 ? 399 THR A CB 1 ATOM 3105 O OG1 . THR A 1 399 ? 27.765 37.585 -5.288 1.00 10.72 ? 399 THR A OG1 1 ATOM 3106 C CG2 . THR A 1 399 ? 29.756 36.796 -4.028 1.00 10.11 ? 399 THR A CG2 1 ATOM 3107 N N . LEU A 1 400 ? 28.495 41.192 -4.202 1.00 8.09 ? 400 LEU A N 1 ATOM 3108 C CA . LEU A 1 400 ? 27.888 42.453 -4.638 1.00 7.15 ? 400 LEU A CA 1 ATOM 3109 C C . LEU A 1 400 ? 28.826 43.175 -5.591 1.00 6.60 ? 400 LEU A C 1 ATOM 3110 O O . LEU A 1 400 ? 30.056 43.129 -5.446 1.00 7.11 ? 400 LEU A O 1 ATOM 3111 C CB . LEU A 1 400 ? 27.626 43.364 -3.415 1.00 8.10 ? 400 LEU A CB 1 ATOM 3112 C CG . LEU A 1 400 ? 26.955 44.748 -3.631 1.00 7.36 ? 400 LEU A CG 1 ATOM 3113 C CD1 . LEU A 1 400 ? 26.096 45.139 -2.393 1.00 9.91 ? 400 LEU A CD1 1 ATOM 3114 C CD2 . LEU A 1 400 ? 27.993 45.825 -3.970 1.00 8.16 ? 400 LEU A CD2 1 ATOM 3115 N N . SER A 1 401 ? 28.212 43.804 -6.615 1.00 7.08 ? 401 SER A N 1 ATOM 3116 C CA . SER A 1 401 ? 28.973 44.750 -7.449 1.00 6.88 ? 401 SER A CA 1 ATOM 3117 C C . SER A 1 401 ? 28.103 45.982 -7.647 1.00 6.50 ? 401 SER A C 1 ATOM 3118 O O . SER A 1 401 ? 26.895 45.962 -7.451 1.00 6.61 ? 401 SER A O 1 ATOM 3119 C CB . SER A 1 401 ? 29.372 44.153 -8.797 1.00 8.19 ? 401 SER A CB 1 ATOM 3120 O OG . SER A 1 401 ? 28.259 44.129 -9.694 1.00 7.60 ? 401 SER A OG 1 ATOM 3121 N N . GLY A 1 402 ? 28.780 47.082 -7.984 1.00 7.01 ? 402 GLY A N 1 ATOM 3122 C CA . GLY A 1 402 ? 28.128 48.371 -8.226 1.00 6.60 ? 402 GLY A CA 1 ATOM 3123 C C . GLY A 1 402 ? 28.722 49.455 -7.319 1.00 6.45 ? 402 GLY A C 1 ATOM 3124 O O . GLY A 1 402 ? 29.795 49.251 -6.694 1.00 8.49 ? 402 GLY A O 1 ATOM 3125 N N . ASP A 1 403 ? 28.110 50.627 -7.297 1.00 6.10 ? 403 ASP A N 1 ATOM 3126 C CA . ASP A 1 403 ? 28.586 51.733 -6.455 1.00 6.32 ? 403 ASP A CA 1 ATOM 3127 C C . ASP A 1 403 ? 27.464 52.185 -5.556 1.00 7.34 ? 403 ASP A C 1 ATOM 3128 O O . ASP A 1 403 ? 26.335 51.640 -5.567 1.00 8.22 ? 403 ASP A O 1 ATOM 3129 C CB . ASP A 1 403 ? 29.105 52.902 -7.342 1.00 7.27 ? 403 ASP A CB 1 ATOM 3130 C CG . ASP A 1 403 ? 28.023 53.629 -8.065 1.00 9.14 ? 403 ASP A CG 1 ATOM 3131 O OD1 . ASP A 1 403 ? 26.891 53.186 -8.132 1.00 12.07 ? 403 ASP A OD1 1 ATOM 3132 O OD2 . ASP A 1 403 ? 28.378 54.708 -8.566 1.00 11.87 ? 403 ASP A OD2 1 ATOM 3133 N N . PHE A 1 404 ? 27.765 53.213 -4.768 1.00 6.05 ? 404 PHE A N 1 ATOM 3134 C CA . PHE A 1 404 ? 26.812 53.782 -3.810 1.00 6.35 ? 404 PHE A CA 1 ATOM 3135 C C . PHE A 1 404 ? 26.705 55.273 -3.986 1.00 6.32 ? 404 PHE A C 1 ATOM 3136 O O . PHE A 1 404 ? 26.820 56.039 -3.056 1.00 7.33 ? 404 PHE A O 1 ATOM 3137 C CB . PHE A 1 404 ? 27.156 53.354 -2.341 1.00 6.86 ? 404 PHE A CB 1 ATOM 3138 C CG . PHE A 1 404 ? 27.121 51.843 -2.149 1.00 6.20 ? 404 PHE A CG 1 ATOM 3139 C CD1 . PHE A 1 404 ? 25.874 51.221 -2.052 1.00 6.68 ? 404 PHE A CD1 1 ATOM 3140 C CD2 . PHE A 1 404 ? 28.279 51.100 -2.111 1.00 7.09 ? 404 PHE A CD2 1 ATOM 3141 C CE1 . PHE A 1 404 ? 25.815 49.804 -1.909 1.00 6.56 ? 404 PHE A CE1 1 ATOM 3142 C CE2 . PHE A 1 404 ? 28.204 49.685 -1.973 1.00 7.65 ? 404 PHE A CE2 1 ATOM 3143 C CZ . PHE A 1 404 ? 26.968 49.076 -1.872 1.00 7.50 ? 404 PHE A CZ 1 ATOM 3144 N N . PHE A 1 405 ? 26.423 55.664 -5.235 1.00 6.99 ? 405 PHE A N 1 ATOM 3145 C CA . PHE A 1 405 ? 26.096 57.069 -5.546 1.00 5.94 ? 405 PHE A CA 1 ATOM 3146 C C . PHE A 1 405 ? 24.734 57.048 -6.255 1.00 7.26 ? 405 PHE A C 1 ATOM 3147 O O . PHE A 1 405 ? 24.408 56.048 -6.950 1.00 8.17 ? 405 PHE A O 1 ATOM 3148 C CB . PHE A 1 405 ? 27.130 57.685 -6.519 1.00 7.28 ? 405 PHE A CB 1 ATOM 3149 C CG . PHE A 1 405 ? 28.514 57.785 -5.976 1.00 6.38 ? 405 PHE A CG 1 ATOM 3150 C CD1 . PHE A 1 405 ? 28.754 58.591 -4.871 1.00 7.63 ? 405 PHE A CD1 1 ATOM 3151 C CD2 . PHE A 1 405 ? 29.554 57.080 -6.567 1.00 7.63 ? 405 PHE A CD2 1 ATOM 3152 C CE1 . PHE A 1 405 ? 30.095 58.689 -4.324 1.00 7.38 ? 405 PHE A CE1 1 ATOM 3153 C CE2 . PHE A 1 405 ? 30.873 57.156 -6.024 1.00 7.23 ? 405 PHE A CE2 1 ATOM 3154 C CZ . PHE A 1 405 ? 31.111 57.969 -4.899 1.00 6.12 ? 405 PHE A CZ 1 ATOM 3155 N N . THR A 1 406 ? 23.930 58.096 -6.157 1.00 7.62 ? 406 THR A N 1 ATOM 3156 C CA . THR A 1 406 ? 24.161 59.308 -5.381 1.00 6.82 ? 406 THR A CA 1 ATOM 3157 C C . THR A 1 406 ? 23.510 59.168 -4.014 1.00 6.78 ? 406 THR A C 1 ATOM 3158 O O . THR A 1 406 ? 22.342 58.776 -3.858 1.00 8.27 ? 406 THR A O 1 ATOM 3159 C CB . THR A 1 406 ? 23.620 60.541 -6.151 1.00 6.36 ? 406 THR A CB 1 ATOM 3160 O OG1 . THR A 1 406 ? 24.538 60.703 -7.224 1.00 8.22 ? 406 THR A OG1 1 ATOM 3161 C CG2 . THR A 1 406 ? 23.501 61.817 -5.336 1.00 6.95 ? 406 THR A CG2 1 ATOM 3162 N N . TYR A 1 407 ? 24.259 59.533 -2.993 1.00 6.40 ? 407 TYR A N 1 ATOM 3163 C CA . TYR A 1 407 ? 23.848 59.442 -1.602 1.00 6.06 ? 407 TYR A CA 1 ATOM 3164 C C . TYR A 1 407 ? 22.727 60.426 -1.280 1.00 7.85 ? 407 TYR A C 1 ATOM 3165 O O . TYR A 1 407 ? 22.758 61.560 -1.718 1.00 8.06 ? 407 TYR A O 1 ATOM 3166 C CB . TYR A 1 407 ? 25.062 59.784 -0.736 1.00 7.36 ? 407 TYR A CB 1 ATOM 3167 C CG . TYR A 1 407 ? 24.862 59.880 0.765 1.00 6.38 ? 407 TYR A CG 1 ATOM 3168 C CD1 . TYR A 1 407 ? 24.400 58.801 1.519 1.00 7.52 ? 407 TYR A CD1 1 ATOM 3169 C CD2 . TYR A 1 407 ? 25.174 61.042 1.427 1.00 8.11 ? 407 TYR A CD2 1 ATOM 3170 C CE1 . TYR A 1 407 ? 24.245 58.914 2.879 1.00 7.81 ? 407 TYR A CE1 1 ATOM 3171 C CE2 . TYR A 1 407 ? 25.035 61.147 2.770 1.00 8.13 ? 407 TYR A CE2 1 ATOM 3172 C CZ . TYR A 1 407 ? 24.569 60.080 3.492 1.00 7.84 ? 407 TYR A CZ 1 ATOM 3173 O OH . TYR A 1 407 ? 24.471 60.234 4.837 1.00 9.05 ? 407 TYR A OH 1 ATOM 3174 N N . ALA A 1 408 ? 21.755 59.958 -0.491 1.00 8.77 ? 408 ALA A N 1 ATOM 3175 C CA . ALA A 1 408 ? 20.828 60.850 0.203 1.00 7.65 ? 408 ALA A CA 1 ATOM 3176 C C . ALA A 1 408 ? 20.752 60.386 1.649 1.00 7.07 ? 408 ALA A C 1 ATOM 3177 O O . ALA A 1 408 ? 20.637 59.193 1.884 1.00 8.42 ? 408 ALA A O 1 ATOM 3178 C CB . ALA A 1 408 ? 19.403 60.809 -0.452 1.00 8.78 ? 408 ALA A CB 1 ATOM 3179 N N . ASP A 1 409 ? 20.856 61.328 2.586 1.00 7.94 ? 409 ASP A N 1 ATOM 3180 C CA . ASP A 1 409 ? 20.772 60.970 4.012 1.00 9.30 ? 409 ASP A CA 1 ATOM 3181 C C . ASP A 1 409 ? 19.352 61.034 4.532 1.00 10.38 ? 409 ASP A C 1 ATOM 3182 O O . ASP A 1 409 ? 19.051 60.374 5.555 1.00 11.12 ? 409 ASP A O 1 ATOM 3183 C CB . ASP A 1 409 ? 21.673 61.866 4.890 1.00 8.05 ? 409 ASP A CB 1 ATOM 3184 C CG . ASP A 1 409 ? 21.397 63.358 4.800 1.00 7.55 ? 409 ASP A CG 1 ATOM 3185 O OD1 . ASP A 1 409 ? 20.809 63.870 3.806 1.00 8.45 ? 409 ASP A OD1 1 ATOM 3186 O OD2 . ASP A 1 409 ? 21.871 64.088 5.732 1.00 11.28 ? 409 ASP A OD2 1 ATOM 3187 N N . ARG A 1 410 ? 18.447 61.739 3.846 1.00 9.18 ? 410 ARG A N 1 ATOM 3188 C CA . ARG A 1 410 ? 17.025 61.831 4.291 1.00 9.42 ? 410 ARG A CA 1 ATOM 3189 C C . ARG A 1 410 ? 16.224 62.466 3.166 1.00 9.99 ? 410 ARG A C 1 ATOM 3190 O O . ARG A 1 410 ? 16.785 63.220 2.300 1.00 10.38 ? 410 ARG A O 1 ATOM 3191 C CB . ARG A 1 410 ? 16.865 62.679 5.553 1.00 11.53 ? 410 ARG A CB 1 ATOM 3192 C CG . ARG A 1 410 ? 17.246 64.142 5.386 1.00 13.47 ? 410 ARG A CG 1 ATOM 3193 C CD . ARG A 1 410 ? 17.076 64.773 6.769 1.00 22.81 ? 410 ARG A CD 1 ATOM 3194 N NE . ARG A 1 410 ? 17.821 66.000 7.010 1.00 26.18 ? 410 ARG A NE 1 ATOM 3195 C CZ . ARG A 1 410 ? 17.378 67.223 6.778 1.00 32.06 ? 410 ARG A CZ 1 ATOM 3196 N NH1 . ARG A 1 410 ? 16.150 67.411 6.263 1.00 31.30 ? 410 ARG A NH1 1 ATOM 3197 N NH2 . ARG A 1 410 ? 18.165 68.253 7.102 1.00 25.06 ? 410 ARG A NH2 1 ATOM 3198 N N . SER A 1 411 ? 14.945 62.111 3.095 1.00 10.99 ? 411 SER A N 1 ATOM 3199 C CA . SER A 1 411 ? 13.984 62.726 2.168 1.00 10.22 ? 411 SER A CA 1 ATOM 3200 C C . SER A 1 411 ? 14.495 62.762 0.734 1.00 9.56 ? 411 SER A C 1 ATOM 3201 O O . SER A 1 411 ? 14.934 61.749 0.203 1.00 11.40 ? 411 SER A O 1 ATOM 3202 C CB A SER A 1 411 ? 13.359 63.936 2.668 0.50 19.03 ? 411 SER A CB 1 ATOM 3203 C CB B SER A 1 411 ? 13.646 64.155 2.713 0.50 18.60 ? 411 SER A CB 1 ATOM 3204 O OG A SER A 1 411 ? 14.308 64.946 2.893 0.50 25.20 ? 411 SER A OG 1 ATOM 3205 O OG B SER A 1 411 ? 12.512 64.647 2.025 0.50 25.78 ? 411 SER A OG 1 ATOM 3206 N N . ASP A 1 412 ? 14.455 63.951 0.141 1.00 10.01 ? 412 ASP A N 1 ATOM 3207 C CA . ASP A 1 412 ? 14.931 64.176 -1.219 1.00 9.55 ? 412 ASP A CA 1 ATOM 3208 C C . ASP A 1 412 ? 16.268 64.915 -1.212 1.00 8.49 ? 412 ASP A C 1 ATOM 3209 O O . ASP A 1 412 ? 16.639 65.540 -2.188 1.00 9.68 ? 412 ASP A O 1 ATOM 3210 C CB . ASP A 1 412 ? 13.883 64.965 -2.026 1.00 11.28 ? 412 ASP A CB 1 ATOM 3211 C CG . ASP A 1 412 ? 13.707 66.388 -1.524 1.00 10.53 ? 412 ASP A CG 1 ATOM 3212 O OD1 . ASP A 1 412 ? 14.188 66.707 -0.427 1.00 11.25 ? 412 ASP A OD1 1 ATOM 3213 O OD2 . ASP A 1 412 ? 13.078 67.188 -2.237 1.00 13.67 ? 412 ASP A OD2 1 ATOM 3214 N N . ASN A 1 413 ? 16.971 64.852 -0.088 1.00 8.70 ? 413 ASN A N 1 ATOM 3215 C CA . ASN A 1 413 ? 18.226 65.617 0.075 1.00 8.43 ? 413 ASN A CA 1 ATOM 3216 C C . ASN A 1 413 ? 19.381 64.755 -0.481 1.00 7.50 ? 413 ASN A C 1 ATOM 3217 O O . ASN A 1 413 ? 20.077 64.051 0.307 1.00 8.11 ? 413 ASN A O 1 ATOM 3218 C CB . ASN A 1 413 ? 18.475 65.913 1.540 1.00 8.80 ? 413 ASN A CB 1 ATOM 3219 C CG . ASN A 1 413 ? 17.565 67.005 2.138 1.00 9.30 ? 413 ASN A CG 1 ATOM 3220 O OD1 . ASN A 1 413 ? 17.845 67.477 3.223 1.00 11.79 ? 413 ASN A OD1 1 ATOM 3221 N ND2 . ASN A 1 413 ? 16.488 67.393 1.459 1.00 10.31 ? 413 ASN A ND2 1 ATOM 3222 N N . TYR A 1 414 ? 19.558 64.802 -1.798 1.00 7.66 ? 414 TYR A N 1 ATOM 3223 C CA . TYR A 1 414 ? 20.649 64.073 -2.521 1.00 8.32 ? 414 TYR A CA 1 ATOM 3224 C C . TYR A 1 414 ? 21.871 64.983 -2.579 1.00 7.83 ? 414 TYR A C 1 ATOM 3225 O O . TYR A 1 414 ? 21.791 66.154 -2.927 1.00 8.37 ? 414 TYR A O 1 ATOM 3226 C CB . TYR A 1 414 ? 20.186 63.735 -3.945 1.00 7.91 ? 414 TYR A CB 1 ATOM 3227 C CG . TYR A 1 414 ? 19.181 62.597 -3.968 1.00 7.39 ? 414 TYR A CG 1 ATOM 3228 C CD1 . TYR A 1 414 ? 17.816 62.851 -3.734 1.00 9.00 ? 414 TYR A CD1 1 ATOM 3229 C CD2 . TYR A 1 414 ? 19.601 61.275 -4.166 1.00 7.98 ? 414 TYR A CD2 1 ATOM 3230 C CE1 . TYR A 1 414 ? 16.904 61.760 -3.696 1.00 8.73 ? 414 TYR A CE1 1 ATOM 3231 C CE2 . TYR A 1 414 ? 18.712 60.188 -4.119 1.00 8.62 ? 414 TYR A CE2 1 ATOM 3232 C CZ . TYR A 1 414 ? 17.373 60.466 -3.887 1.00 8.83 ? 414 TYR A CZ 1 ATOM 3233 O OH . TYR A 1 414 ? 16.526 59.348 -3.852 1.00 8.95 ? 414 TYR A OH 1 ATOM 3234 N N . TRP A 1 415 ? 22.998 64.349 -2.274 1.00 6.98 ? 415 TRP A N 1 ATOM 3235 C CA . TRP A 1 415 ? 24.259 65.067 -2.167 1.00 7.09 ? 415 TRP A CA 1 ATOM 3236 C C . TRP A 1 415 ? 24.992 65.125 -3.505 1.00 7.10 ? 415 TRP A C 1 ATOM 3237 O O . TRP A 1 415 ? 26.111 64.654 -3.605 1.00 10.16 ? 415 TRP A O 1 ATOM 3238 C CB . TRP A 1 415 ? 25.118 64.414 -1.074 1.00 7.52 ? 415 TRP A CB 1 ATOM 3239 C CG . TRP A 1 415 ? 24.542 64.507 0.310 1.00 7.46 ? 415 TRP A CG 1 ATOM 3240 C CD1 . TRP A 1 415 ? 23.212 64.255 0.716 1.00 7.12 ? 415 TRP A CD1 1 ATOM 3241 C CD2 . TRP A 1 415 ? 25.278 64.742 1.496 1.00 7.42 ? 415 TRP A CD2 1 ATOM 3242 N NE1 . TRP A 1 415 ? 23.131 64.343 2.086 1.00 7.32 ? 415 TRP A NE1 1 ATOM 3243 C CE2 . TRP A 1 415 ? 24.378 64.630 2.584 1.00 8.27 ? 415 TRP A CE2 1 ATOM 3244 C CE3 . TRP A 1 415 ? 26.638 65.022 1.768 1.00 8.29 ? 415 TRP A CE3 1 ATOM 3245 C CZ2 . TRP A 1 415 ? 24.789 64.780 3.934 1.00 9.22 ? 415 TRP A CZ2 1 ATOM 3246 C CZ3 . TRP A 1 415 ? 27.053 65.175 3.086 1.00 8.56 ? 415 TRP A CZ3 1 ATOM 3247 C CH2 . TRP A 1 415 ? 26.136 65.047 4.157 1.00 9.34 ? 415 TRP A CH2 1 ATOM 3248 N N . SER A 1 416 ? 24.364 65.666 -4.534 1.00 7.16 ? 416 SER A N 1 ATOM 3249 C CA . SER A 1 416 ? 25.014 65.801 -5.815 1.00 7.46 ? 416 SER A CA 1 ATOM 3250 C C . SER A 1 416 ? 25.601 67.217 -6.018 1.00 6.28 ? 416 SER A C 1 ATOM 3251 O O . SER A 1 416 ? 26.282 67.425 -6.991 1.00 7.45 ? 416 SER A O 1 ATOM 3252 C CB . SER A 1 416 ? 24.034 65.430 -6.945 1.00 6.82 ? 416 SER A CB 1 ATOM 3253 O OG . SER A 1 416 ? 22.746 65.989 -6.754 1.00 8.27 ? 416 SER A OG 1 ATOM 3254 N N . GLY A 1 417 ? 25.368 68.141 -5.098 1.00 5.84 ? 417 GLY A N 1 ATOM 3255 C CA . GLY A 1 417 ? 25.949 69.492 -5.250 1.00 7.17 ? 417 GLY A CA 1 ATOM 3256 C C . GLY A 1 417 ? 27.475 69.480 -5.164 1.00 5.85 ? 417 GLY A C 1 ATOM 3257 O O . GLY A 1 417 ? 28.159 70.205 -5.906 1.00 6.47 ? 417 GLY A O 1 ATOM 3258 N N . TYR A 1 418 ? 28.019 68.647 -4.268 1.00 6.12 ? 418 TYR A N 1 ATOM 3259 C CA . TYR A 1 418 ? 29.479 68.665 -4.064 1.00 5.03 ? 418 TYR A CA 1 ATOM 3260 C C . TYR A 1 418 ? 30.242 68.054 -5.250 1.00 5.66 ? 418 TYR A C 1 ATOM 3261 O O . TYR A 1 418 ? 31.476 68.058 -5.281 1.00 6.28 ? 418 TYR A O 1 ATOM 3262 C CB . TYR A 1 418 ? 29.856 67.972 -2.728 1.00 5.91 ? 418 TYR A CB 1 ATOM 3263 C CG . TYR A 1 418 ? 29.976 66.450 -2.785 1.00 6.05 ? 418 TYR A CG 1 ATOM 3264 C CD1 . TYR A 1 418 ? 28.866 65.638 -2.657 1.00 7.27 ? 418 TYR A CD1 1 ATOM 3265 C CD2 . TYR A 1 418 ? 31.240 65.857 -2.941 1.00 5.94 ? 418 TYR A CD2 1 ATOM 3266 C CE1 . TYR A 1 418 ? 28.969 64.215 -2.671 1.00 6.41 ? 418 TYR A CE1 1 ATOM 3267 C CE2 . TYR A 1 418 ? 31.366 64.473 -2.952 1.00 6.35 ? 418 TYR A CE2 1 ATOM 3268 C CZ . TYR A 1 418 ? 30.223 63.695 -2.819 1.00 5.68 ? 418 TYR A CZ 1 ATOM 3269 O OH . TYR A 1 418 ? 30.409 62.322 -2.793 1.00 6.99 ? 418 TYR A OH 1 ATOM 3270 N N . TYR A 1 419 ? 29.531 67.463 -6.227 1.00 5.94 ? 419 TYR A N 1 ATOM 3271 C CA . TYR A 1 419 ? 30.214 67.015 -7.450 1.00 5.97 ? 419 TYR A CA 1 ATOM 3272 C C . TYR A 1 419 ? 30.739 68.233 -8.244 1.00 6.07 ? 419 TYR A C 1 ATOM 3273 O O . TYR A 1 419 ? 31.567 68.059 -9.109 1.00 6.18 ? 419 TYR A O 1 ATOM 3274 C CB . TYR A 1 419 ? 29.279 66.216 -8.339 1.00 5.60 ? 419 TYR A CB 1 ATOM 3275 C CG . TYR A 1 419 ? 28.628 65.032 -7.698 1.00 5.29 ? 419 TYR A CG 1 ATOM 3276 C CD1 . TYR A 1 419 ? 29.209 64.349 -6.599 1.00 5.54 ? 419 TYR A CD1 1 ATOM 3277 C CD2 . TYR A 1 419 ? 27.450 64.529 -8.260 1.00 5.61 ? 419 TYR A CD2 1 ATOM 3278 C CE1 . TYR A 1 419 ? 28.631 63.183 -6.080 1.00 6.13 ? 419 TYR A CE1 1 ATOM 3279 C CE2 . TYR A 1 419 ? 26.845 63.374 -7.734 1.00 5.69 ? 419 TYR A CE2 1 ATOM 3280 C CZ . TYR A 1 419 ? 27.473 62.716 -6.644 1.00 6.53 ? 419 TYR A CZ 1 ATOM 3281 O OH . TYR A 1 419 ? 26.889 61.547 -6.115 1.00 7.12 ? 419 TYR A OH 1 ATOM 3282 N N . THR A 1 420 ? 30.273 69.438 -7.916 1.00 5.64 ? 420 THR A N 1 ATOM 3283 C CA . THR A 1 420 ? 30.647 70.671 -8.621 1.00 6.02 ? 420 THR A CA 1 ATOM 3284 C C . THR A 1 420 ? 31.169 71.765 -7.720 1.00 6.79 ? 420 THR A C 1 ATOM 3285 O O . THR A 1 420 ? 31.953 72.595 -8.198 1.00 7.38 ? 420 THR A O 1 ATOM 3286 C CB . THR A 1 420 ? 29.402 71.190 -9.404 1.00 5.99 ? 420 THR A CB 1 ATOM 3287 O OG1 . THR A 1 420 ? 28.970 70.137 -10.270 1.00 6.81 ? 420 THR A OG1 1 ATOM 3288 C CG2 . THR A 1 420 ? 29.729 72.433 -10.317 1.00 9.56 ? 420 THR A CG2 1 ATOM 3289 N N . SER A 1 421 ? 30.803 71.791 -6.430 1.00 5.88 ? 421 SER A N 1 ATOM 3290 C CA . SER A 1 421 ? 31.183 72.911 -5.565 1.00 5.69 ? 421 SER A CA 1 ATOM 3291 C C . SER A 1 421 ? 32.665 73.248 -5.598 1.00 5.86 ? 421 SER A C 1 ATOM 3292 O O . SER A 1 421 ? 33.528 72.355 -5.543 1.00 6.67 ? 421 SER A O 1 ATOM 3293 C CB . SER A 1 421 ? 30.814 72.565 -4.119 1.00 5.88 ? 421 SER A CB 1 ATOM 3294 O OG . SER A 1 421 ? 29.423 72.439 -4.029 1.00 7.00 ? 421 SER A OG 1 ATOM 3295 N N . ARG A 1 422 ? 32.979 74.537 -5.623 1.00 5.84 ? 422 ARG A N 1 ATOM 3296 C CA . ARG A 1 422 ? 34.371 75.016 -5.711 1.00 5.83 ? 422 ARG A CA 1 ATOM 3297 C C . ARG A 1 422 ? 35.126 74.388 -6.904 1.00 6.46 ? 422 ARG A C 1 ATOM 3298 O O . ARG A 1 422 ? 36.117 73.692 -6.747 1.00 6.15 ? 422 ARG A O 1 ATOM 3299 C CB . ARG A 1 422 ? 35.115 74.822 -4.376 1.00 7.52 ? 422 ARG A CB 1 ATOM 3300 C CG . ARG A 1 422 ? 34.875 75.933 -3.357 1.00 8.12 ? 422 ARG A CG 1 ATOM 3301 C CD . ARG A 1 422 ? 33.436 76.027 -2.815 1.00 7.59 ? 422 ARG A CD 1 ATOM 3302 N NE . ARG A 1 422 ? 33.459 76.999 -1.721 1.00 8.24 ? 422 ARG A NE 1 ATOM 3303 C CZ . ARG A 1 422 ? 33.526 76.679 -0.437 1.00 8.17 ? 422 ARG A CZ 1 ATOM 3304 N NH1 . ARG A 1 422 ? 33.486 75.425 -0.035 1.00 8.51 ? 422 ARG A NH1 1 ATOM 3305 N NH2 . ARG A 1 422 ? 33.637 77.630 0.457 1.00 9.01 ? 422 ARG A NH2 1 ATOM 3306 N N . PRO A 1 423 ? 34.622 74.610 -8.104 1.00 5.63 ? 423 PRO A N 1 ATOM 3307 C CA . PRO A 1 423 ? 35.230 73.972 -9.276 1.00 5.65 ? 423 PRO A CA 1 ATOM 3308 C C . PRO A 1 423 ? 36.634 74.433 -9.609 1.00 6.01 ? 423 PRO A C 1 ATOM 3309 O O . PRO A 1 423 ? 37.355 73.705 -10.280 1.00 6.57 ? 423 PRO A O 1 ATOM 3310 C CB . PRO A 1 423 ? 34.184 74.232 -10.388 1.00 7.27 ? 423 PRO A CB 1 ATOM 3311 C CG . PRO A 1 423 ? 33.635 75.608 -10.007 1.00 7.03 ? 423 PRO A CG 1 ATOM 3312 C CD . PRO A 1 423 ? 33.468 75.465 -8.478 1.00 6.88 ? 423 PRO A CD 1 ATOM 3313 N N . TYR A 1 424 ? 37.029 75.636 -9.196 1.00 6.37 ? 424 TYR A N 1 ATOM 3314 C CA . TYR A 1 424 ? 38.407 76.058 -9.478 1.00 6.54 ? 424 TYR A CA 1 ATOM 3315 C C . TYR A 1 424 ? 39.374 75.035 -8.864 1.00 6.47 ? 424 TYR A C 1 ATOM 3316 O O . TYR A 1 424 ? 40.371 74.675 -9.489 1.00 6.69 ? 424 TYR A O 1 ATOM 3317 C CB . TYR A 1 424 ? 38.655 77.454 -8.828 1.00 6.56 ? 424 TYR A CB 1 ATOM 3318 C CG . TYR A 1 424 ? 40.027 77.972 -9.059 1.00 6.62 ? 424 TYR A CG 1 ATOM 3319 C CD1 . TYR A 1 424 ? 40.280 78.744 -10.180 1.00 9.04 ? 424 TYR A CD1 1 ATOM 3320 C CD2 . TYR A 1 424 ? 41.062 77.716 -8.180 1.00 7.67 ? 424 TYR A CD2 1 ATOM 3321 C CE1 . TYR A 1 424 ? 41.533 79.251 -10.433 1.00 9.53 ? 424 TYR A CE1 1 ATOM 3322 C CE2 . TYR A 1 424 ? 42.361 78.228 -8.463 1.00 10.24 ? 424 TYR A CE2 1 ATOM 3323 C CZ . TYR A 1 424 ? 42.564 79.002 -9.606 1.00 8.34 ? 424 TYR A CZ 1 ATOM 3324 O OH . TYR A 1 424 ? 43.801 79.573 -9.923 1.00 11.96 ? 424 TYR A OH 1 ATOM 3325 N N . HIS A 1 425 ? 39.106 74.613 -7.638 1.00 6.47 ? 425 HIS A N 1 ATOM 3326 C CA . HIS A 1 425 ? 40.023 73.726 -6.910 1.00 5.45 ? 425 HIS A CA 1 ATOM 3327 C C . HIS A 1 425 ? 39.910 72.291 -7.371 1.00 6.29 ? 425 HIS A C 1 ATOM 3328 O O . HIS A 1 425 ? 40.868 71.544 -7.310 1.00 5.56 ? 425 HIS A O 1 ATOM 3329 C CB . HIS A 1 425 ? 39.808 73.891 -5.410 1.00 7.06 ? 425 HIS A CB 1 ATOM 3330 C CG . HIS A 1 425 ? 39.867 75.320 -4.993 1.00 8.16 ? 425 HIS A CG 1 ATOM 3331 N ND1 . HIS A 1 425 ? 38.765 76.146 -5.009 1.00 11.64 ? 425 HIS A ND1 1 ATOM 3332 C CD2 . HIS A 1 425 ? 40.920 76.098 -4.664 1.00 6.49 ? 425 HIS A CD2 1 ATOM 3333 C CE1 . HIS A 1 425 ? 39.134 77.365 -4.659 1.00 7.50 ? 425 HIS A CE1 1 ATOM 3334 N NE2 . HIS A 1 425 ? 40.433 77.358 -4.436 1.00 12.23 ? 425 HIS A NE2 1 ATOM 3335 N N . LYS A 1 426 ? 38.734 71.923 -7.880 1.00 5.32 ? 426 LYS A N 1 ATOM 3336 C CA . LYS A 1 426 ? 38.581 70.610 -8.502 1.00 6.37 ? 426 LYS A CA 1 ATOM 3337 C C . LYS A 1 426 ? 39.488 70.547 -9.756 1.00 5.41 ? 426 LYS A C 1 ATOM 3338 O O . LYS A 1 426 ? 40.094 69.500 -10.028 1.00 6.08 ? 426 LYS A O 1 ATOM 3339 C CB . LYS A 1 426 ? 37.103 70.425 -8.891 1.00 6.03 ? 426 LYS A CB 1 ATOM 3340 C CG . LYS A 1 426 ? 36.215 70.029 -7.720 1.00 5.76 ? 426 LYS A CG 1 ATOM 3341 C CD . LYS A 1 426 ? 34.716 70.063 -8.068 1.00 7.30 ? 426 LYS A CD 1 ATOM 3342 C CE . LYS A 1 426 ? 33.816 69.151 -7.189 1.00 5.71 ? 426 LYS A CE 1 ATOM 3343 N NZ . LYS A 1 426 ? 33.838 69.612 -5.734 1.00 6.73 ? 426 LYS A NZ 1 ATOM 3344 N N . ARG A 1 427 ? 39.524 71.607 -10.547 1.00 5.31 ? 427 ARG A N 1 ATOM 3345 C CA . ARG A 1 427 ? 40.395 71.634 -11.710 1.00 5.43 ? 427 ARG A CA 1 ATOM 3346 C C . ARG A 1 427 ? 41.860 71.686 -11.276 1.00 6.10 ? 427 ARG A C 1 ATOM 3347 O O . ARG A 1 427 ? 42.683 70.994 -11.843 1.00 6.17 ? 427 ARG A O 1 ATOM 3348 C CB . ARG A 1 427 ? 40.016 72.818 -12.610 1.00 7.10 ? 427 ARG A CB 1 ATOM 3349 C CG . ARG A 1 427 ? 41.015 73.138 -13.706 1.00 7.96 ? 427 ARG A CG 1 ATOM 3350 C CD . ARG A 1 427 ? 41.152 72.028 -14.743 1.00 8.54 ? 427 ARG A CD 1 ATOM 3351 N NE . ARG A 1 427 ? 42.170 72.419 -15.715 1.00 9.74 ? 427 ARG A NE 1 ATOM 3352 C CZ . ARG A 1 427 ? 42.996 71.593 -16.339 1.00 9.10 ? 427 ARG A CZ 1 ATOM 3353 N NH1 . ARG A 1 427 ? 42.943 70.289 -16.154 1.00 9.33 ? 427 ARG A NH1 1 ATOM 3354 N NH2 . ARG A 1 427 ? 43.889 72.101 -17.167 1.00 10.33 ? 427 ARG A NH2 1 ATOM 3355 N N . MET A 1 428 ? 42.163 72.473 -10.244 1.00 5.64 ? 428 MET A N 1 ATOM 3356 C CA . MET A 1 428 ? 43.538 72.536 -9.742 1.00 5.71 ? 428 MET A CA 1 ATOM 3357 C C . MET A 1 428 ? 44.030 71.111 -9.320 1.00 5.11 ? 428 MET A C 1 ATOM 3358 O O . MET A 1 428 ? 45.209 70.789 -9.509 1.00 5.87 ? 428 MET A O 1 ATOM 3359 C CB . MET A 1 428 ? 43.613 73.509 -8.560 1.00 7.51 ? 428 MET A CB 1 ATOM 3360 C CG . MET A 1 428 ? 45.048 73.885 -8.189 1.00 7.04 ? 428 MET A CG 1 ATOM 3361 S SD . MET A 1 428 ? 44.960 75.189 -6.915 1.00 8.94 ? 428 MET A SD 1 ATOM 3362 C CE . MET A 1 428 ? 46.701 75.683 -6.843 1.00 10.30 ? 428 MET A CE 1 ATOM 3363 N N . ASP A 1 429 ? 43.151 70.324 -8.693 1.00 6.16 ? 429 ASP A N 1 ATOM 3364 C CA . ASP A 1 429 ? 43.504 68.936 -8.318 1.00 5.55 ? 429 ASP A CA 1 ATOM 3365 C C . ASP A 1 429 ? 44.082 68.139 -9.496 1.00 6.38 ? 429 ASP A C 1 ATOM 3366 O O . ASP A 1 429 ? 45.076 67.441 -9.333 1.00 5.42 ? 429 ASP A O 1 ATOM 3367 C CB . ASP A 1 429 ? 42.247 68.229 -7.784 1.00 7.12 ? 429 ASP A CB 1 ATOM 3368 C CG . ASP A 1 429 ? 42.514 66.750 -7.478 1.00 6.82 ? 429 ASP A CG 1 ATOM 3369 O OD1 . ASP A 1 429 ? 43.030 66.528 -6.360 1.00 7.43 ? 429 ASP A OD1 1 ATOM 3370 O OD2 . ASP A 1 429 ? 42.215 65.877 -8.346 1.00 7.02 ? 429 ASP A OD2 1 ATOM 3371 N N . ARG A 1 430 ? 43.434 68.238 -10.658 1.00 4.96 ? 430 ARG A N 1 ATOM 3372 C CA . ARG A 1 430 ? 43.876 67.474 -11.811 1.00 5.60 ? 430 ARG A CA 1 ATOM 3373 C C . ARG A 1 430 ? 45.186 68.008 -12.375 1.00 4.78 ? 430 ARG A C 1 ATOM 3374 O O . ARG A 1 430 ? 46.026 67.206 -12.864 1.00 6.05 ? 430 ARG A O 1 ATOM 3375 C CB . ARG A 1 430 ? 42.805 67.487 -12.900 1.00 5.14 ? 430 ARG A CB 1 ATOM 3376 C CG . ARG A 1 430 ? 41.544 66.777 -12.500 1.00 6.80 ? 430 ARG A CG 1 ATOM 3377 C CD . ARG A 1 430 ? 41.795 65.303 -12.032 1.00 5.80 ? 430 ARG A CD 1 ATOM 3378 N NE . ARG A 1 430 ? 40.557 64.547 -12.041 1.00 6.83 ? 430 ARG A NE 1 ATOM 3379 C CZ . ARG A 1 430 ? 39.833 64.201 -10.967 1.00 5.45 ? 430 ARG A CZ 1 ATOM 3380 N NH1 . ARG A 1 430 ? 40.216 64.533 -9.746 1.00 6.29 ? 430 ARG A NH1 1 ATOM 3381 N NH2 . ARG A 1 430 ? 38.714 63.521 -11.132 1.00 6.62 ? 430 ARG A NH2 1 ATOM 3382 N N . VAL A 1 431 ? 45.387 69.325 -12.313 1.00 5.18 ? 431 VAL A N 1 ATOM 3383 C CA . VAL A 1 431 ? 46.664 69.915 -12.787 1.00 5.44 ? 431 VAL A CA 1 ATOM 3384 C C . VAL A 1 431 ? 47.792 69.391 -11.844 1.00 6.46 ? 431 VAL A C 1 ATOM 3385 O O . VAL A 1 431 ? 48.822 68.901 -12.314 1.00 5.78 ? 431 VAL A O 1 ATOM 3386 C CB . VAL A 1 431 ? 46.533 71.430 -12.752 1.00 5.20 ? 431 VAL A CB 1 ATOM 3387 C CG1 . VAL A 1 431 ? 47.899 72.047 -13.085 1.00 7.16 ? 431 VAL A CG1 1 ATOM 3388 C CG2 . VAL A 1 431 ? 45.508 71.868 -13.813 1.00 6.72 ? 431 VAL A CG2 1 ATOM 3389 N N . LEU A 1 432 ? 47.599 69.514 -10.529 1.00 5.45 ? 432 LEU A N 1 ATOM 3390 C CA . LEU A 1 432 ? 48.639 69.065 -9.596 1.00 5.75 ? 432 LEU A CA 1 ATOM 3391 C C . LEU A 1 432 ? 48.828 67.546 -9.691 1.00 5.27 ? 432 LEU A C 1 ATOM 3392 O O . LEU A 1 432 ? 49.968 67.070 -9.573 1.00 6.07 ? 432 LEU A O 1 ATOM 3393 C CB . LEU A 1 432 ? 48.307 69.540 -8.191 1.00 6.74 ? 432 LEU A CB 1 ATOM 3394 C CG . LEU A 1 432 ? 49.309 69.147 -7.092 1.00 6.66 ? 432 LEU A CG 1 ATOM 3395 C CD1 . LEU A 1 432 ? 50.729 69.662 -7.402 1.00 6.74 ? 432 LEU A CD1 1 ATOM 3396 C CD2 . LEU A 1 432 ? 48.821 69.748 -5.776 1.00 7.40 ? 432 LEU A CD2 1 ATOM 3397 N N . MET A 1 433 ? 47.750 66.777 -9.931 1.00 4.78 ? 433 MET A N 1 ATOM 3398 C CA . MET A 1 433 ? 47.921 65.326 -10.116 1.00 5.57 ? 433 MET A CA 1 ATOM 3399 C C . MET A 1 433 ? 49.006 65.028 -11.144 1.00 5.63 ? 433 MET A C 1 ATOM 3400 O O . MET A 1 433 ? 49.869 64.175 -10.986 1.00 5.47 ? 433 MET A O 1 ATOM 3401 C CB . MET A 1 433 ? 46.577 64.729 -10.630 1.00 5.65 ? 433 MET A CB 1 ATOM 3402 C CG . MET A 1 433 ? 46.669 63.235 -10.870 1.00 6.04 ? 433 MET A CG 1 ATOM 3403 S SD . MET A 1 433 ? 45.099 62.570 -11.570 1.00 8.49 ? 433 MET A SD 1 ATOM 3404 C CE . MET A 1 433 ? 45.122 63.232 -13.252 1.00 10.54 ? 433 MET A CE 1 ATOM 3405 N N . HIS A 1 434 ? 48.867 65.698 -12.293 1.00 5.24 ? 434 HIS A N 1 ATOM 3406 C CA . HIS A 1 434 ? 49.781 65.516 -13.420 1.00 5.55 ? 434 HIS A CA 1 ATOM 3407 C C . HIS A 1 434 ? 51.177 66.030 -13.112 1.00 5.55 ? 434 HIS A C 1 ATOM 3408 O O . HIS A 1 434 ? 52.122 65.372 -13.435 1.00 5.98 ? 434 HIS A O 1 ATOM 3409 C CB . HIS A 1 434 ? 49.260 66.194 -14.683 1.00 7.13 ? 434 HIS A CB 1 ATOM 3410 C CG . HIS A 1 434 ? 50.289 66.229 -15.766 1.00 5.55 ? 434 HIS A CG 1 ATOM 3411 N ND1 . HIS A 1 434 ? 50.661 65.101 -16.458 1.00 10.47 ? 434 HIS A ND1 1 ATOM 3412 C CD2 . HIS A 1 434 ? 51.099 67.224 -16.194 1.00 4.52 ? 434 HIS A CD2 1 ATOM 3413 C CE1 . HIS A 1 434 ? 51.626 65.415 -17.304 1.00 5.31 ? 434 HIS A CE1 1 ATOM 3414 N NE2 . HIS A 1 434 ? 51.916 66.693 -17.157 1.00 9.62 ? 434 HIS A NE2 1 ATOM 3415 N N A TYR A 1 435 ? 51.277 67.189 -12.471 0.50 20.00 ? 435 TYR A N 1 ATOM 3416 N N B TYR A 1 435 ? 51.274 67.179 -12.466 0.50 20.00 ? 435 TYR A N 1 ATOM 3417 C CA A TYR A 1 435 ? 52.586 67.744 -12.134 0.50 20.00 ? 435 TYR A CA 1 ATOM 3418 C CA B TYR A 1 435 ? 52.584 67.702 -12.144 0.50 20.00 ? 435 TYR A CA 1 ATOM 3419 C C A TYR A 1 435 ? 53.338 66.852 -11.136 0.50 20.00 ? 435 TYR A C 1 ATOM 3420 C C B TYR A 1 435 ? 53.341 66.863 -11.122 0.50 20.00 ? 435 TYR A C 1 ATOM 3421 O O A TYR A 1 435 ? 54.551 66.734 -11.220 0.50 6.10 ? 435 TYR A O 1 ATOM 3422 O O B TYR A 1 435 ? 54.555 66.751 -11.202 0.50 6.10 ? 435 TYR A O 1 ATOM 3423 C CB A TYR A 1 435 ? 52.456 69.155 -11.552 0.50 20.00 ? 435 TYR A CB 1 ATOM 3424 C CB B TYR A 1 435 ? 52.516 69.184 -11.802 0.50 20.00 ? 435 TYR A CB 1 ATOM 3425 C CG A TYR A 1 435 ? 52.347 70.306 -12.532 0.50 20.00 ? 435 TYR A CG 1 ATOM 3426 C CG B TYR A 1 435 ? 52.414 70.024 -13.060 0.50 20.00 ? 435 TYR A CG 1 ATOM 3427 C CD1 A TYR A 1 435 ? 51.326 70.362 -13.473 0.50 20.00 ? 435 TYR A CD1 1 ATOM 3428 C CD1 B TYR A 1 435 ? 53.415 69.989 -14.038 0.50 20.00 ? 435 TYR A CD1 1 ATOM 3429 C CD2 A TYR A 1 435 ? 53.210 71.388 -12.447 0.50 20.00 ? 435 TYR A CD2 1 ATOM 3430 C CD2 B TYR A 1 435 ? 51.293 70.782 -13.318 0.50 20.00 ? 435 TYR A CD2 1 ATOM 3431 C CE1 A TYR A 1 435 ? 51.204 71.430 -14.344 0.50 20.00 ? 435 TYR A CE1 1 ATOM 3432 C CE1 B TYR A 1 435 ? 53.308 70.743 -15.205 0.50 20.00 ? 435 TYR A CE1 1 ATOM 3433 C CE2 A TYR A 1 435 ? 53.098 72.459 -13.319 0.50 20.00 ? 435 TYR A CE2 1 ATOM 3434 C CE2 B TYR A 1 435 ? 51.185 71.543 -14.464 0.50 20.00 ? 435 TYR A CE2 1 ATOM 3435 C CZ A TYR A 1 435 ? 52.090 72.473 -14.264 0.50 20.00 ? 435 TYR A CZ 1 ATOM 3436 C CZ B TYR A 1 435 ? 52.193 71.523 -15.408 0.50 20.00 ? 435 TYR A CZ 1 ATOM 3437 O OH A TYR A 1 435 ? 51.963 73.541 -15.128 0.50 20.00 ? 435 TYR A OH 1 ATOM 3438 O OH B TYR A 1 435 ? 52.092 72.271 -16.563 0.50 20.00 ? 435 TYR A OH 1 ATOM 3439 N N . VAL A 1 436 ? 52.626 66.240 -10.191 1.00 4.92 ? 436 VAL A N 1 ATOM 3440 C CA . VAL A 1 436 ? 53.302 65.349 -9.260 1.00 5.59 ? 436 VAL A CA 1 ATOM 3441 C C . VAL A 1 436 ? 53.805 64.111 -10.047 1.00 5.57 ? 436 VAL A C 1 ATOM 3442 O O . VAL A 1 436 ? 54.967 63.658 -9.875 1.00 5.78 ? 436 VAL A O 1 ATOM 3443 C CB . VAL A 1 436 ? 52.360 64.892 -8.131 1.00 5.99 ? 436 VAL A CB 1 ATOM 3444 C CG1 . VAL A 1 436 ? 52.878 63.659 -7.371 1.00 7.69 ? 436 VAL A CG1 1 ATOM 3445 C CG2 . VAL A 1 436 ? 52.182 66.050 -7.132 1.00 6.52 ? 436 VAL A CG2 1 ATOM 3446 N N . ARG A 1 437 ? 52.953 63.543 -10.917 1.00 5.03 ? 437 ARG A N 1 ATOM 3447 C CA . ARG A 1 437 ? 53.422 62.388 -11.671 1.00 6.43 ? 437 ARG A CA 1 ATOM 3448 C C . ARG A 1 437 ? 54.658 62.761 -12.511 1.00 6.37 ? 437 ARG A C 1 ATOM 3449 O O . ARG A 1 437 ? 55.659 61.991 -12.584 1.00 6.15 ? 437 ARG A O 1 ATOM 3450 C CB . ARG A 1 437 ? 52.322 61.889 -12.618 1.00 6.94 ? 437 ARG A CB 1 ATOM 3451 C CG . ARG A 1 437 ? 52.844 60.880 -13.680 1.00 7.63 ? 437 ARG A CG 1 ATOM 3452 C CD . ARG A 1 437 ? 51.671 60.417 -14.556 1.00 7.46 ? 437 ARG A CD 1 ATOM 3453 N NE . ARG A 1 437 ? 52.231 59.699 -15.719 1.00 7.15 ? 437 ARG A NE 1 ATOM 3454 C CZ . ARG A 1 437 ? 51.466 58.880 -16.446 1.00 6.90 ? 437 ARG A CZ 1 ATOM 3455 N NH1 . ARG A 1 437 ? 50.202 58.652 -16.138 1.00 8.13 ? 437 ARG A NH1 1 ATOM 3456 N NH2 . ARG A 1 437 ? 51.974 58.321 -17.556 1.00 7.91 ? 437 ARG A NH2 1 ATOM 3457 N N . ALA A 1 438 ? 54.596 63.923 -13.218 1.00 5.44 ? 438 ALA A N 1 ATOM 3458 C CA . ALA A 1 438 ? 55.721 64.282 -14.092 1.00 5.63 ? 438 ALA A CA 1 ATOM 3459 C C . ALA A 1 438 ? 57.004 64.576 -13.303 1.00 5.69 ? 438 ALA A C 1 ATOM 3460 O O . ALA A 1 438 ? 58.112 64.230 -13.739 1.00 6.26 ? 438 ALA A O 1 ATOM 3461 C CB . ALA A 1 438 ? 55.323 65.508 -14.973 1.00 7.53 ? 438 ALA A CB 1 ATOM 3462 N N . ALA A 1 439 ? 56.875 65.265 -12.139 1.00 6.37 ? 439 ALA A N 1 ATOM 3463 C CA . ALA A 1 439 ? 58.039 65.530 -11.314 1.00 6.11 ? 439 ALA A CA 1 ATOM 3464 C C . ALA A 1 439 ? 58.650 64.240 -10.776 1.00 5.66 ? 439 ALA A C 1 ATOM 3465 O O . ALA A 1 439 ? 59.896 64.113 -10.753 1.00 6.35 ? 439 ALA A O 1 ATOM 3466 C CB . ALA A 1 439 ? 57.680 66.471 -10.200 1.00 6.87 ? 439 ALA A CB 1 ATOM 3467 N N . GLU A 1 440 ? 57.831 63.317 -10.293 1.00 5.79 ? 440 GLU A N 1 ATOM 3468 C CA . GLU A 1 440 ? 58.401 62.075 -9.765 1.00 6.14 ? 440 GLU A CA 1 ATOM 3469 C C . GLU A 1 440 ? 59.035 61.267 -10.915 1.00 5.67 ? 440 GLU A C 1 ATOM 3470 O O . GLU A 1 440 ? 60.135 60.676 -10.708 1.00 6.49 ? 440 GLU A O 1 ATOM 3471 C CB . GLU A 1 440 ? 57.328 61.236 -9.050 1.00 6.93 ? 440 GLU A CB 1 ATOM 3472 C CG . GLU A 1 440 ? 56.775 61.889 -7.788 1.00 7.91 ? 440 GLU A CG 1 ATOM 3473 C CD . GLU A 1 440 ? 56.110 60.878 -6.870 1.00 9.52 ? 440 GLU A CD 1 ATOM 3474 O OE1 . GLU A 1 440 ? 55.002 60.411 -7.161 1.00 10.92 ? 440 GLU A OE1 1 ATOM 3475 O OE2 . GLU A 1 440 ? 56.761 60.587 -5.848 1.00 11.17 ? 440 GLU A OE2 1 ATOM 3476 N N . MET A 1 441 ? 58.436 61.245 -12.113 1.00 5.74 ? 441 MET A N 1 ATOM 3477 C CA . MET A 1 441 ? 58.996 60.477 -13.205 1.00 5.71 ? 441 MET A CA 1 ATOM 3478 C C . MET A 1 441 ? 60.301 61.082 -13.757 1.00 6.35 ? 441 MET A C 1 ATOM 3479 O O . MET A 1 441 ? 61.311 60.385 -13.877 1.00 7.11 ? 441 MET A O 1 ATOM 3480 C CB . MET A 1 441 ? 57.941 60.352 -14.305 1.00 6.66 ? 441 MET A CB 1 ATOM 3481 C CG . MET A 1 441 ? 58.433 59.598 -15.533 1.00 6.31 ? 441 MET A CG 1 ATOM 3482 S SD . MET A 1 441 ? 57.186 59.343 -16.814 1.00 7.14 ? 441 MET A SD 1 ATOM 3483 C CE . MET A 1 441 ? 56.045 58.158 -15.972 1.00 8.89 ? 441 MET A CE 1 ATOM 3484 N N . LEU A 1 442 ? 60.292 62.403 -13.993 1.00 6.16 ? 442 LEU A N 1 ATOM 3485 C CA . LEU A 1 442 ? 61.484 63.068 -14.548 1.00 6.43 ? 442 LEU A CA 1 ATOM 3486 C C . LEU A 1 442 ? 62.662 62.950 -13.640 1.00 7.01 ? 442 LEU A C 1 ATOM 3487 O O . LEU A 1 442 ? 63.785 62.771 -14.133 1.00 7.69 ? 442 LEU A O 1 ATOM 3488 C CB . LEU A 1 442 ? 61.191 64.562 -14.860 1.00 7.05 ? 442 LEU A CB 1 ATOM 3489 C CG . LEU A 1 442 ? 60.528 64.764 -16.229 1.00 6.79 ? 442 LEU A CG 1 ATOM 3490 C CD1 . LEU A 1 442 ? 59.939 66.165 -16.283 1.00 8.29 ? 442 LEU A CD1 1 ATOM 3491 C CD2 . LEU A 1 442 ? 61.583 64.610 -17.353 1.00 9.95 ? 442 LEU A CD2 1 ATOM 3492 N N . SER A 1 443 ? 62.433 63.024 -12.316 1.00 5.91 ? 443 SER A N 1 ATOM 3493 C CA . SER A 1 443 ? 63.560 62.979 -11.385 1.00 6.95 ? 443 SER A CA 1 ATOM 3494 C C . SER A 1 443 ? 63.949 61.554 -11.030 1.00 7.23 ? 443 SER A C 1 ATOM 3495 O O . SER A 1 443 ? 65.056 61.369 -10.529 1.00 8.43 ? 443 SER A O 1 ATOM 3496 C CB . SER A 1 443 ? 63.278 63.783 -10.139 1.00 6.74 ? 443 SER A CB 1 ATOM 3497 O OG . SER A 1 443 ? 62.181 63.241 -9.387 1.00 8.04 ? 443 SER A OG 1 ATOM 3498 N N . ALA A 1 444 ? 63.137 60.563 -11.337 1.00 6.56 ? 444 ALA A N 1 ATOM 3499 C CA . ALA A 1 444 ? 63.448 59.175 -10.986 1.00 6.92 ? 444 ALA A CA 1 ATOM 3500 C C . ALA A 1 444 ? 64.592 58.638 -11.803 1.00 7.62 ? 444 ALA A C 1 ATOM 3501 O O . ALA A 1 444 ? 65.226 57.628 -11.371 1.00 8.50 ? 444 ALA A O 1 ATOM 3502 C CB . ALA A 1 444 ? 62.229 58.259 -11.228 1.00 8.04 ? 444 ALA A CB 1 ATOM 3503 N N . TRP A 1 445 ? 64.855 59.173 -12.988 1.00 7.96 ? 445 TRP A N 1 ATOM 3504 C CA . TRP A 1 445 ? 65.892 58.601 -13.870 1.00 9.31 ? 445 TRP A CA 1 ATOM 3505 C C . TRP A 1 445 ? 67.289 58.649 -13.264 1.00 9.48 ? 445 TRP A C 1 ATOM 3506 O O . TRP A 1 445 ? 68.142 57.880 -13.629 1.00 11.33 ? 445 TRP A O 1 ATOM 3507 C CB . TRP A 1 445 ? 65.893 59.353 -15.208 1.00 8.55 ? 445 TRP A CB 1 ATOM 3508 C CG . TRP A 1 445 ? 64.618 59.196 -15.975 1.00 6.86 ? 445 TRP A CG 1 ATOM 3509 C CD1 . TRP A 1 445 ? 63.645 60.144 -16.116 1.00 7.96 ? 445 TRP A CD1 1 ATOM 3510 C CD2 . TRP A 1 445 ? 64.135 58.024 -16.655 1.00 6.28 ? 445 TRP A CD2 1 ATOM 3511 N NE1 . TRP A 1 445 ? 62.585 59.638 -16.831 1.00 7.30 ? 445 TRP A NE1 1 ATOM 3512 C CE2 . TRP A 1 445 ? 62.865 58.340 -17.177 1.00 6.17 ? 445 TRP A CE2 1 ATOM 3513 C CE3 . TRP A 1 445 ? 64.664 56.727 -16.891 1.00 7.46 ? 445 TRP A CE3 1 ATOM 3514 C CZ2 . TRP A 1 445 ? 62.115 57.427 -17.916 1.00 7.46 ? 445 TRP A CZ2 1 ATOM 3515 C CZ3 . TRP A 1 445 ? 63.933 55.819 -17.631 1.00 8.58 ? 445 TRP A CZ3 1 ATOM 3516 C CH2 . TRP A 1 445 ? 62.657 56.153 -18.141 1.00 8.51 ? 445 TRP A CH2 1 ATOM 3517 N N . HIS A 1 446 ? 67.533 59.588 -12.376 1.00 9.41 ? 446 HIS A N 1 ATOM 3518 C CA . HIS A 1 446 ? 68.823 59.746 -11.727 1.00 10.56 ? 446 HIS A CA 1 ATOM 3519 C C . HIS A 1 446 ? 68.678 59.666 -10.236 1.00 9.90 ? 446 HIS A C 1 ATOM 3520 O O . HIS A 1 446 ? 67.639 59.885 -9.646 1.00 10.08 ? 446 HIS A O 1 ATOM 3521 C CB . HIS A 1 446 ? 69.416 61.138 -11.956 1.00 11.63 ? 446 HIS A CB 1 ATOM 3522 C CG . HIS A 1 446 ? 69.848 61.402 -13.367 1.00 14.63 ? 446 HIS A CG 1 ATOM 3523 N ND1 . HIS A 1 446 ? 69.077 62.124 -14.261 1.00 16.48 ? 446 HIS A ND1 1 ATOM 3524 C CD2 . HIS A 1 446 ? 70.980 61.065 -14.031 1.00 19.38 ? 446 HIS A CD2 1 ATOM 3525 C CE1 . HIS A 1 446 ? 69.712 62.222 -15.412 1.00 22.91 ? 446 HIS A CE1 1 ATOM 3526 N NE2 . HIS A 1 446 ? 70.862 61.596 -15.305 1.00 19.16 ? 446 HIS A NE2 1 ATOM 3527 N N . SER A 1 447 ? 69.820 59.401 -9.605 1.00 11.46 ? 447 SER A N 1 ATOM 3528 C CA . SER A 1 447 ? 69.964 59.487 -8.167 1.00 10.10 ? 447 SER A CA 1 ATOM 3529 C C . SER A 1 447 ? 70.430 60.963 -7.907 1.00 10.64 ? 447 SER A C 1 ATOM 3530 O O . SER A 1 447 ? 71.295 61.493 -8.674 1.00 13.51 ? 447 SER A O 1 ATOM 3531 C CB . SER A 1 447 ? 71.064 58.532 -7.778 1.00 17.62 ? 447 SER A CB 1 ATOM 3532 O OG . SER A 1 447 ? 71.029 58.397 -6.412 1.00 21.06 ? 447 SER A OG 1 ATOM 3533 N N . TRP A 1 448 ? 69.936 61.641 -6.893 1.00 9.65 ? 448 TRP A N 1 ATOM 3534 C CA . TRP A 1 448 ? 70.292 63.035 -6.670 1.00 10.97 ? 448 TRP A CA 1 ATOM 3535 C C . TRP A 1 448 ? 70.989 63.230 -5.349 1.00 11.98 ? 448 TRP A C 1 ATOM 3536 O O . TRP A 1 448 ? 70.611 62.609 -4.355 1.00 13.41 ? 448 TRP A O 1 ATOM 3537 C CB . TRP A 1 448 ? 69.030 63.923 -6.663 1.00 10.99 ? 448 TRP A CB 1 ATOM 3538 C CG . TRP A 1 448 ? 68.356 63.956 -8.051 1.00 8.97 ? 448 TRP A CG 1 ATOM 3539 C CD1 . TRP A 1 448 ? 67.512 63.042 -8.553 1.00 10.01 ? 448 TRP A CD1 1 ATOM 3540 C CD2 . TRP A 1 448 ? 68.521 64.966 -9.060 1.00 8.79 ? 448 TRP A CD2 1 ATOM 3541 N NE1 . TRP A 1 448 ? 67.106 63.383 -9.825 1.00 9.46 ? 448 TRP A NE1 1 ATOM 3542 C CE2 . TRP A 1 448 ? 67.710 64.573 -10.158 1.00 8.33 ? 448 TRP A CE2 1 ATOM 3543 C CE3 . TRP A 1 448 ? 69.266 66.169 -9.142 1.00 10.96 ? 448 TRP A CE3 1 ATOM 3544 C CZ2 . TRP A 1 448 ? 67.602 65.345 -11.314 1.00 10.29 ? 448 TRP A CZ2 1 ATOM 3545 C CZ3 . TRP A 1 448 ? 69.154 66.936 -10.291 1.00 9.71 ? 448 TRP A CZ3 1 ATOM 3546 C CH2 . TRP A 1 448 ? 68.328 66.519 -11.356 1.00 10.08 ? 448 TRP A CH2 1 ATOM 3547 N N . ASP A 1 449 ? 71.968 64.138 -5.329 1.00 13.51 ? 449 ASP A N 1 ATOM 3548 C CA . ASP A 1 449 ? 72.624 64.481 -4.098 1.00 16.03 ? 449 ASP A CA 1 ATOM 3549 C C . ASP A 1 449 ? 71.603 65.118 -3.166 1.00 16.26 ? 449 ASP A C 1 ATOM 3550 O O . ASP A 1 449 ? 70.685 65.812 -3.616 1.00 14.79 ? 449 ASP A O 1 ATOM 3551 C CB . ASP A 1 449 ? 73.755 65.475 -4.386 1.00 22.62 ? 449 ASP A CB 1 ATOM 3552 C CG . ASP A 1 449 ? 74.547 65.812 -3.116 1.00 27.74 ? 449 ASP A CG 1 ATOM 3553 O OD1 . ASP A 1 449 ? 75.406 64.981 -2.702 1.00 35.46 ? 449 ASP A OD1 1 ATOM 3554 O OD2 . ASP A 1 449 ? 74.283 66.845 -2.498 1.00 27.69 ? 449 ASP A OD2 1 ATOM 3555 N N . GLY A 1 450 ? 71.755 64.918 -1.856 1.00 15.17 ? 450 GLY A N 1 ATOM 3556 C CA . GLY A 1 450 ? 70.803 65.519 -0.932 1.00 17.00 ? 450 GLY A CA 1 ATOM 3557 C C . GLY A 1 450 ? 70.733 67.046 -1.023 1.00 16.94 ? 450 GLY A C 1 ATOM 3558 O O . GLY A 1 450 ? 69.698 67.675 -0.684 1.00 17.18 ? 450 GLY A O 1 ATOM 3559 N N . MET A 1 451 ? 71.808 67.688 -1.452 1.00 16.22 ? 451 MET A N 1 ATOM 3560 C CA . MET A 1 451 ? 71.800 69.139 -1.554 1.00 17.85 ? 451 MET A CA 1 ATOM 3561 C C . MET A 1 451 ? 70.843 69.653 -2.627 1.00 13.73 ? 451 MET A C 1 ATOM 3562 O O . MET A 1 451 ? 70.512 70.827 -2.653 1.00 17.40 ? 451 MET A O 1 ATOM 3563 C CB . MET A 1 451 ? 73.227 69.673 -1.845 1.00 24.64 ? 451 MET A CB 1 ATOM 3564 C CG . MET A 1 451 ? 74.213 69.454 -0.690 1.00 34.04 ? 451 MET A CG 1 ATOM 3565 S SD . MET A 1 451 ? 73.762 70.291 0.851 1.00 49.10 ? 451 MET A SD 1 ATOM 3566 C CE . MET A 1 451 ? 72.892 69.060 1.848 1.00 39.89 ? 451 MET A CE 1 ATOM 3567 N N . ALA A 1 452 ? 70.425 68.767 -3.535 1.00 12.94 ? 452 ALA A N 1 ATOM 3568 C CA . ALA A 1 452 ? 69.486 69.159 -4.588 1.00 12.87 ? 452 ALA A CA 1 ATOM 3569 C C . ALA A 1 452 ? 68.042 69.275 -4.054 1.00 12.74 ? 452 ALA A C 1 ATOM 3570 O O . ALA A 1 452 ? 67.195 69.798 -4.768 1.00 13.69 ? 452 ALA A O 1 ATOM 3571 C CB . ALA A 1 452 ? 69.526 68.185 -5.702 1.00 13.52 ? 452 ALA A CB 1 ATOM 3572 N N . ARG A 1 453 ? 67.766 68.758 -2.846 1.00 11.35 ? 453 ARG A N 1 ATOM 3573 C CA . ARG A 1 453 ? 66.450 68.870 -2.186 1.00 12.01 ? 453 ARG A CA 1 ATOM 3574 C C . ARG A 1 453 ? 65.322 68.289 -3.051 1.00 10.92 ? 453 ARG A C 1 ATOM 3575 O O . ARG A 1 453 ? 64.184 68.753 -2.960 1.00 12.60 ? 453 ARG A O 1 ATOM 3576 C CB . ARG A 1 453 ? 66.140 70.330 -1.837 1.00 13.91 ? 453 ARG A CB 1 ATOM 3577 C CG . ARG A 1 453 ? 67.244 70.933 -0.977 1.00 14.33 ? 453 ARG A CG 1 ATOM 3578 C CD . ARG A 1 453 ? 67.088 72.442 -0.818 1.00 22.98 ? 453 ARG A CD 1 ATOM 3579 N NE . ARG A 1 453 ? 65.933 72.706 0.016 1.00 20.54 ? 453 ARG A NE 1 ATOM 3580 C CZ . ARG A 1 453 ? 65.430 73.920 0.233 1.00 28.13 ? 453 ARG A CZ 1 ATOM 3581 N NH1 . ARG A 1 453 ? 65.984 75.008 -0.335 1.00 24.30 ? 453 ARG A NH1 1 ATOM 3582 N NH2 . ARG A 1 453 ? 64.368 74.046 1.019 1.00 23.65 ? 453 ARG A NH2 1 ATOM 3583 N N . ILE A 1 454 ? 65.608 67.260 -3.827 1.00 9.35 ? 454 ILE A N 1 ATOM 3584 C CA . ILE A 1 454 ? 64.606 66.667 -4.699 1.00 9.11 ? 454 ILE A CA 1 ATOM 3585 C C . ILE A 1 454 ? 63.601 65.907 -3.845 1.00 10.11 ? 454 ILE A C 1 ATOM 3586 O O . ILE A 1 454 ? 62.380 66.113 -3.972 1.00 9.24 ? 454 ILE A O 1 ATOM 3587 C CB . ILE A 1 454 ? 65.284 65.710 -5.705 1.00 9.19 ? 454 ILE A CB 1 ATOM 3588 C CG1 . ILE A 1 454 ? 66.219 66.510 -6.640 1.00 11.26 ? 454 ILE A CG1 1 ATOM 3589 C CG2 . ILE A 1 454 ? 64.227 64.899 -6.475 1.00 10.73 ? 454 ILE A CG2 1 ATOM 3590 C CD1 . ILE A 1 454 ? 65.559 67.560 -7.513 1.00 13.52 ? 454 ILE A CD1 1 ATOM 3591 N N . GLU A 1 455 ? 64.054 65.035 -2.969 1.00 10.26 ? 455 GLU A N 1 ATOM 3592 C CA . GLU A 1 455 ? 63.121 64.243 -2.134 1.00 9.49 ? 455 GLU A CA 1 ATOM 3593 C C . GLU A 1 455 ? 62.316 65.193 -1.245 1.00 9.53 ? 455 GLU A C 1 ATOM 3594 O O . GLU A 1 455 ? 61.106 64.937 -1.034 1.00 9.70 ? 455 GLU A O 1 ATOM 3595 C CB . GLU A 1 455 ? 63.876 63.251 -1.224 1.00 13.02 ? 455 GLU A CB 1 ATOM 3596 C CG . GLU A 1 455 ? 64.484 62.052 -1.932 1.00 13.39 ? 455 GLU A CG 1 ATOM 3597 C CD . GLU A 1 455 ? 65.897 62.332 -2.536 1.00 13.09 ? 455 GLU A CD 1 ATOM 3598 O OE1 . GLU A 1 455 ? 66.396 63.499 -2.400 1.00 14.38 ? 455 GLU A OE1 1 ATOM 3599 O OE2 . GLU A 1 455 ? 66.447 61.373 -3.110 1.00 12.52 ? 455 GLU A OE2 1 ATOM 3600 N N . GLU A 1 456 ? 62.889 66.260 -0.706 1.00 10.23 ? 456 GLU A N 1 ATOM 3601 C CA . GLU A 1 456 ? 62.174 67.186 0.114 1.00 8.68 ? 456 GLU A CA 1 ATOM 3602 C C . GLU A 1 456 ? 61.024 67.822 -0.668 1.00 9.48 ? 456 GLU A C 1 ATOM 3603 O O . GLU A 1 456 ? 59.878 67.922 -0.196 1.00 9.34 ? 456 GLU A O 1 ATOM 3604 C CB . GLU A 1 456 ? 63.163 68.298 0.550 1.00 12.40 ? 456 GLU A CB 1 ATOM 3605 C CG . GLU A 1 456 ? 62.535 69.391 1.340 1.00 15.59 ? 456 GLU A CG 1 ATOM 3606 C CD . GLU A 1 456 ? 63.458 70.591 1.566 1.00 21.92 ? 456 GLU A CD 1 ATOM 3607 O OE1 . GLU A 1 456 ? 64.683 70.457 1.319 1.00 20.68 ? 456 GLU A OE1 1 ATOM 3608 O OE2 . GLU A 1 456 ? 62.954 71.676 1.983 1.00 23.30 ? 456 GLU A OE2 1 ATOM 3609 N N . ARG A 1 457 ? 61.312 68.312 -1.873 1.00 8.04 ? 457 ARG A N 1 ATOM 3610 C CA . ARG A 1 457 ? 60.235 68.974 -2.638 1.00 8.50 ? 457 ARG A CA 1 ATOM 3611 C C . ARG A 1 457 ? 59.140 67.997 -3.109 1.00 6.83 ? 457 ARG A C 1 ATOM 3612 O O . ARG A 1 457 ? 57.970 68.359 -3.063 1.00 7.76 ? 457 ARG A O 1 ATOM 3613 C CB . ARG A 1 457 ? 60.861 69.744 -3.843 1.00 8.12 ? 457 ARG A CB 1 ATOM 3614 C CG . ARG A 1 457 ? 61.188 71.205 -3.583 1.00 11.22 ? 457 ARG A CG 1 ATOM 3615 C CD . ARG A 1 457 ? 62.145 71.398 -2.475 1.00 14.29 ? 457 ARG A CD 1 ATOM 3616 N NE . ARG A 1 457 ? 62.449 72.834 -2.216 1.00 14.98 ? 457 ARG A NE 1 ATOM 3617 C CZ . ARG A 1 457 ? 63.376 73.571 -2.855 1.00 18.64 ? 457 ARG A CZ 1 ATOM 3618 N NH1 . ARG A 1 457 ? 64.137 73.062 -3.836 1.00 14.36 ? 457 ARG A NH1 1 ATOM 3619 N NH2 . ARG A 1 457 ? 63.546 74.855 -2.494 1.00 18.50 ? 457 ARG A NH2 1 ATOM 3620 N N . LEU A 1 458 ? 59.536 66.779 -3.485 1.00 7.21 ? 458 LEU A N 1 ATOM 3621 C CA . LEU A 1 458 ? 58.544 65.794 -3.900 1.00 7.85 ? 458 LEU A CA 1 ATOM 3622 C C . LEU A 1 458 ? 57.692 65.382 -2.702 1.00 8.44 ? 458 LEU A C 1 ATOM 3623 O O . LEU A 1 458 ? 56.467 65.182 -2.896 1.00 8.58 ? 458 LEU A O 1 ATOM 3624 C CB . LEU A 1 458 ? 59.250 64.567 -4.490 1.00 8.41 ? 458 LEU A CB 1 ATOM 3625 C CG . LEU A 1 458 ? 59.919 64.895 -5.875 1.00 7.38 ? 458 LEU A CG 1 ATOM 3626 C CD1 . LEU A 1 458 ? 60.647 63.657 -6.321 1.00 10.09 ? 458 LEU A CD1 1 ATOM 3627 C CD2 . LEU A 1 458 ? 58.864 65.290 -6.957 1.00 9.57 ? 458 LEU A CD2 1 ATOM 3628 N N . GLU A 1 459 ? 58.281 65.244 -1.497 1.00 7.74 ? 459 GLU A N 1 ATOM 3629 C CA . GLU A 1 459 ? 57.457 64.862 -0.352 1.00 7.72 ? 459 GLU A CA 1 ATOM 3630 C C . GLU A 1 459 ? 56.451 65.981 -0.054 1.00 7.40 ? 459 GLU A C 1 ATOM 3631 O O . GLU A 1 459 ? 55.265 65.697 0.203 1.00 7.90 ? 459 GLU A O 1 ATOM 3632 C CB . GLU A 1 459 ? 58.345 64.598 0.847 1.00 9.78 ? 459 GLU A CB 1 ATOM 3633 C CG . GLU A 1 459 ? 57.543 64.292 2.139 1.00 11.67 ? 459 GLU A CG 1 ATOM 3634 C CD . GLU A 1 459 ? 58.425 63.637 3.200 1.00 16.34 ? 459 GLU A CD 1 ATOM 3635 O OE1 . GLU A 1 459 ? 59.058 64.400 3.952 1.00 21.90 ? 459 GLU A OE1 1 ATOM 3636 O OE2 . GLU A 1 459 ? 58.503 62.380 3.269 1.00 20.09 ? 459 GLU A OE2 1 ATOM 3637 N N . GLN A 1 460 ? 56.876 67.230 -0.103 1.00 7.58 ? 460 GLN A N 1 ATOM 3638 C CA . GLN A 1 460 ? 55.945 68.326 0.061 1.00 8.09 ? 460 GLN A CA 1 ATOM 3639 C C . GLN A 1 460 ? 54.809 68.261 -0.952 1.00 7.32 ? 460 GLN A C 1 ATOM 3640 O O . GLN A 1 460 ? 53.657 68.382 -0.574 1.00 8.61 ? 460 GLN A O 1 ATOM 3641 C CB . GLN A 1 460 ? 56.699 69.654 -0.035 1.00 11.63 ? 460 GLN A CB 1 ATOM 3642 C CG . GLN A 1 460 ? 55.814 70.857 0.028 1.00 15.47 ? 460 GLN A CG 1 ATOM 3643 C CD . GLN A 1 460 ? 56.552 72.106 -0.347 1.00 21.72 ? 460 GLN A CD 1 ATOM 3644 O OE1 . GLN A 1 460 ? 57.572 72.053 -1.015 1.00 31.57 ? 460 GLN A OE1 1 ATOM 3645 N NE2 . GLN A 1 460 ? 56.050 73.227 0.085 1.00 24.80 ? 460 GLN A NE2 1 ATOM 3646 N N . ALA A 1 461 ? 55.143 68.069 -2.224 1.00 6.87 ? 461 ALA A N 1 ATOM 3647 C CA . ALA A 1 461 ? 54.097 68.065 -3.247 1.00 7.97 ? 461 ALA A CA 1 ATOM 3648 C C . ALA A 1 461 ? 53.133 66.903 -3.050 1.00 7.24 ? 461 ALA A C 1 ATOM 3649 O O . ALA A 1 461 ? 51.904 67.088 -3.148 1.00 7.54 ? 461 ALA A O 1 ATOM 3650 C CB . ALA A 1 461 ? 54.756 68.002 -4.612 1.00 7.80 ? 461 ALA A CB 1 ATOM 3651 N N . ARG A 1 462 ? 53.655 65.706 -2.756 1.00 6.88 ? 462 ARG A N 1 ATOM 3652 C CA . ARG A 1 462 ? 52.771 64.565 -2.554 1.00 6.31 ? 462 ARG A CA 1 ATOM 3653 C C . ARG A 1 462 ? 51.858 64.792 -1.360 1.00 7.09 ? 462 ARG A C 1 ATOM 3654 O O . ARG A 1 462 ? 50.676 64.424 -1.408 1.00 7.00 ? 462 ARG A O 1 ATOM 3655 C CB . ARG A 1 462 ? 53.547 63.254 -2.286 1.00 7.71 ? 462 ARG A CB 1 ATOM 3656 C CG . ARG A 1 462 ? 54.317 62.702 -3.549 1.00 7.21 ? 462 ARG A CG 1 ATOM 3657 C CD . ARG A 1 462 ? 54.767 61.268 -3.269 1.00 8.04 ? 462 ARG A CD 1 ATOM 3658 N NE . ARG A 1 462 ? 55.657 61.178 -2.077 1.00 8.03 ? 462 ARG A NE 1 ATOM 3659 C CZ . ARG A 1 462 ? 56.972 61.326 -2.167 1.00 10.09 ? 462 ARG A CZ 1 ATOM 3660 N NH1 . ARG A 1 462 ? 57.576 61.531 -3.340 1.00 9.04 ? 462 ARG A NH1 1 ATOM 3661 N NH2 . ARG A 1 462 ? 57.735 61.327 -1.073 1.00 11.80 ? 462 ARG A NH2 1 ATOM 3662 N N . ARG A 1 463 ? 52.384 65.389 -0.282 1.00 6.81 ? 463 ARG A N 1 ATOM 3663 C CA . ARG A 1 463 ? 51.558 65.532 0.916 1.00 6.12 ? 463 ARG A CA 1 ATOM 3664 C C . ARG A 1 463 ? 50.501 66.606 0.744 1.00 7.21 ? 463 ARG A C 1 ATOM 3665 O O . ARG A 1 463 ? 49.402 66.434 1.266 1.00 7.60 ? 463 ARG A O 1 ATOM 3666 C CB . ARG A 1 463 ? 52.461 65.808 2.121 1.00 6.96 ? 463 ARG A CB 1 ATOM 3667 C CG . ARG A 1 463 ? 53.119 64.511 2.552 1.00 8.45 ? 463 ARG A CG 1 ATOM 3668 C CD . ARG A 1 463 ? 54.188 64.749 3.633 1.00 9.69 ? 463 ARG A CD 1 ATOM 3669 N NE . ARG A 1 463 ? 54.688 63.400 3.960 1.00 11.43 ? 463 ARG A NE 1 ATOM 3670 C CZ . ARG A 1 463 ? 55.463 63.129 5.019 1.00 14.38 ? 463 ARG A CZ 1 ATOM 3671 N NH1 . ARG A 1 463 ? 55.826 64.136 5.800 1.00 13.95 ? 463 ARG A NH1 1 ATOM 3672 N NH2 . ARG A 1 463 ? 55.778 61.867 5.287 1.00 15.53 ? 463 ARG A NH2 1 ATOM 3673 N N . GLU A 1 464 ? 50.755 67.705 0.019 1.00 6.73 ? 464 GLU A N 1 ATOM 3674 C CA . GLU A 1 464 ? 49.726 68.727 -0.167 1.00 7.40 ? 464 GLU A CA 1 ATOM 3675 C C . GLU A 1 464 ? 48.626 68.201 -1.091 1.00 7.43 ? 464 GLU A C 1 ATOM 3676 O O . GLU A 1 464 ? 47.450 68.448 -0.842 1.00 7.79 ? 464 GLU A O 1 ATOM 3677 C CB . GLU A 1 464 ? 50.277 70.015 -0.776 1.00 9.60 ? 464 GLU A CB 1 ATOM 3678 C CG . GLU A 1 464 ? 51.427 70.698 0.056 1.00 11.08 ? 464 GLU A CG 1 ATOM 3679 C CD . GLU A 1 464 ? 51.121 71.136 1.458 1.00 16.91 ? 464 GLU A CD 1 ATOM 3680 O OE1 . GLU A 1 464 ? 50.133 70.757 2.079 1.00 15.33 ? 464 GLU A OE1 1 ATOM 3681 O OE2 . GLU A 1 464 ? 51.970 71.903 1.976 1.00 21.49 ? 464 GLU A OE2 1 ATOM 3682 N N . LEU A 1 465 ? 49.008 67.464 -2.148 1.00 6.17 ? 465 LEU A N 1 ATOM 3683 C CA . LEU A 1 465 ? 47.973 66.908 -3.039 1.00 6.12 ? 465 LEU A CA 1 ATOM 3684 C C . LEU A 1 465 ? 47.181 65.817 -2.252 1.00 5.76 ? 465 LEU A C 1 ATOM 3685 O O . LEU A 1 465 ? 45.959 65.723 -2.366 1.00 6.23 ? 465 LEU A O 1 ATOM 3686 C CB . LEU A 1 465 ? 48.622 66.270 -4.284 1.00 7.05 ? 465 LEU A CB 1 ATOM 3687 C CG . LEU A 1 465 ? 47.638 65.615 -5.273 1.00 6.62 ? 465 LEU A CG 1 ATOM 3688 C CD1 . LEU A 1 465 ? 46.560 66.590 -5.714 1.00 7.17 ? 465 LEU A CD1 1 ATOM 3689 C CD2 . LEU A 1 465 ? 48.450 65.053 -6.448 1.00 7.95 ? 465 LEU A CD2 1 ATOM 3690 N N . SER A 1 466 ? 47.886 65.012 -1.449 1.00 5.71 ? 466 SER A N 1 ATOM 3691 C CA . SER A 1 466 ? 47.213 63.975 -0.658 1.00 6.33 ? 466 SER A CA 1 ATOM 3692 C C . SER A 1 466 ? 46.210 64.590 0.350 1.00 5.48 ? 466 SER A C 1 ATOM 3693 O O . SER A 1 466 ? 45.089 64.084 0.484 1.00 5.81 ? 466 SER A O 1 ATOM 3694 C CB . SER A 1 466 ? 48.228 63.142 0.093 1.00 6.09 ? 466 SER A CB 1 ATOM 3695 O OG . SER A 1 466 ? 49.008 62.331 -0.752 1.00 6.72 ? 466 SER A OG 1 ATOM 3696 N N . LEU A 1 467 ? 46.606 65.690 0.998 1.00 5.29 ? 467 LEU A N 1 ATOM 3697 C CA . LEU A 1 467 ? 45.715 66.349 1.955 1.00 5.24 ? 467 LEU A CA 1 ATOM 3698 C C . LEU A 1 467 ? 44.405 66.774 1.256 1.00 5.64 ? 467 LEU A C 1 ATOM 3699 O O . LEU A 1 467 ? 43.323 66.676 1.826 1.00 5.82 ? 467 LEU A O 1 ATOM 3700 C CB . LEU A 1 467 ? 46.456 67.575 2.524 1.00 6.37 ? 467 LEU A CB 1 ATOM 3701 C CG . LEU A 1 467 ? 45.675 68.212 3.659 1.00 10.44 ? 467 LEU A CG 1 ATOM 3702 C CD1 . LEU A 1 467 ? 45.836 67.325 4.898 1.00 16.46 ? 467 LEU A CD1 1 ATOM 3703 C CD2 . LEU A 1 467 ? 46.310 69.616 3.946 1.00 12.56 ? 467 LEU A CD2 1 ATOM 3704 N N . PHE A 1 468 ? 44.545 67.284 0.026 1.00 5.33 ? 468 PHE A N 1 ATOM 3705 C CA . PHE A 1 468 ? 43.361 67.791 -0.682 1.00 6.00 ? 468 PHE A CA 1 ATOM 3706 C C . PHE A 1 468 ? 42.373 66.687 -1.089 1.00 5.56 ? 468 PHE A C 1 ATOM 3707 O O . PHE A 1 468 ? 41.210 67.004 -1.387 1.00 6.59 ? 468 PHE A O 1 ATOM 3708 C CB . PHE A 1 468 ? 43.776 68.612 -1.923 1.00 6.47 ? 468 PHE A CB 1 ATOM 3709 C CG . PHE A 1 468 ? 42.659 69.439 -2.472 1.00 5.05 ? 468 PHE A CG 1 ATOM 3710 C CD1 . PHE A 1 468 ? 42.044 70.398 -1.689 1.00 6.98 ? 468 PHE A CD1 1 ATOM 3711 C CD2 . PHE A 1 468 ? 42.215 69.233 -3.802 1.00 6.63 ? 468 PHE A CD2 1 ATOM 3712 C CE1 . PHE A 1 468 ? 41.001 71.145 -2.182 1.00 6.15 ? 468 PHE A CE1 1 ATOM 3713 C CE2 . PHE A 1 468 ? 41.141 70.013 -4.302 1.00 6.35 ? 468 PHE A CE2 1 ATOM 3714 C CZ . PHE A 1 468 ? 40.555 70.954 -3.488 1.00 6.43 ? 468 PHE A CZ 1 ATOM 3715 N N . GLN A 1 469 ? 42.769 65.425 -1.068 1.00 4.77 ? 469 GLN A N 1 ATOM 3716 C CA . GLN A 1 469 ? 41.839 64.324 -1.316 1.00 5.53 ? 469 GLN A CA 1 ATOM 3717 C C . GLN A 1 469 ? 40.826 64.144 -0.200 1.00 5.53 ? 469 GLN A C 1 ATOM 3718 O O . GLN A 1 469 ? 39.895 63.395 -0.376 1.00 5.80 ? 469 GLN A O 1 ATOM 3719 C CB . GLN A 1 469 ? 42.603 63.012 -1.523 1.00 5.27 ? 469 GLN A CB 1 ATOM 3720 C CG . GLN A 1 469 ? 43.688 63.068 -2.627 1.00 5.36 ? 469 GLN A CG 1 ATOM 3721 C CD . GLN A 1 469 ? 43.169 63.729 -3.892 1.00 6.10 ? 469 GLN A CD 1 ATOM 3722 O OE1 . GLN A 1 469 ? 42.189 63.282 -4.486 1.00 8.82 ? 469 GLN A OE1 1 ATOM 3723 N NE2 . GLN A 1 469 ? 43.824 64.786 -4.300 1.00 4.09 ? 469 GLN A NE2 1 ATOM 3724 N N . HIS A 1 470 ? 41.028 64.793 0.931 1.00 5.29 ? 470 HIS A N 1 ATOM 3725 C CA . HIS A 1 470 ? 40.106 64.747 2.062 1.00 4.85 ? 470 HIS A CA 1 ATOM 3726 C C . HIS A 1 470 ? 38.688 65.056 1.595 1.00 5.68 ? 470 HIS A C 1 ATOM 3727 O O . HIS A 1 470 ? 38.474 65.810 0.666 1.00 6.36 ? 470 HIS A O 1 ATOM 3728 C CB . HIS A 1 470 ? 40.564 65.776 3.100 1.00 5.77 ? 470 HIS A CB 1 ATOM 3729 C CG . HIS A 1 470 ? 39.581 66.023 4.197 1.00 5.34 ? 470 HIS A CG 1 ATOM 3730 N ND1 . HIS A 1 470 ? 38.978 65.011 4.907 1.00 9.13 ? 470 HIS A ND1 1 ATOM 3731 C CD2 . HIS A 1 470 ? 39.103 67.179 4.710 1.00 4.29 ? 470 HIS A CD2 1 ATOM 3732 C CE1 . HIS A 1 470 ? 38.157 65.533 5.797 1.00 5.27 ? 470 HIS A CE1 1 ATOM 3733 N NE2 . HIS A 1 470 ? 38.217 66.844 5.701 1.00 9.83 ? 470 HIS A NE2 1 ATOM 3734 N N . HIS A 1 471 ? 37.733 64.454 2.290 1.00 5.97 ? 471 HIS A N 1 ATOM 3735 C CA . HIS A 1 471 ? 36.300 64.600 1.938 1.00 6.19 ? 471 HIS A CA 1 ATOM 3736 C C . HIS A 1 471 ? 35.715 65.981 2.260 1.00 6.02 ? 471 HIS A C 1 ATOM 3737 O O . HIS A 1 471 ? 34.539 66.157 2.004 1.00 7.08 ? 471 HIS A O 1 ATOM 3738 C CB . HIS A 1 471 ? 35.453 63.450 2.572 1.00 6.17 ? 471 HIS A CB 1 ATOM 3739 C CG . HIS A 1 471 ? 35.528 63.384 4.085 1.00 5.25 ? 471 HIS A CG 1 ATOM 3740 N ND1 . HIS A 1 471 ? 36.471 62.635 4.776 1.00 5.96 ? 471 HIS A ND1 1 ATOM 3741 C CD2 . HIS A 1 471 ? 34.789 64.010 5.038 1.00 5.10 ? 471 HIS A CD2 1 ATOM 3742 C CE1 . HIS A 1 471 ? 36.306 62.812 6.097 1.00 5.48 ? 471 HIS A CE1 1 ATOM 3743 N NE2 . HIS A 1 471 ? 35.293 63.643 6.293 1.00 5.60 ? 471 HIS A NE2 1 ATOM 3744 N N . ASP A 1 472 ? 36.545 66.941 2.721 1.00 6.47 ? 472 ASP A N 1 ATOM 3745 C CA . ASP A 1 472 ? 36.129 68.361 2.722 1.00 6.12 ? 472 ASP A CA 1 ATOM 3746 C C . ASP A 1 472 ? 37.088 69.199 1.872 1.00 6.56 ? 472 ASP A C 1 ATOM 3747 O O . ASP A 1 472 ? 36.999 70.442 1.891 1.00 7.60 ? 472 ASP A O 1 ATOM 3748 C CB . ASP A 1 472 ? 36.008 68.969 4.134 1.00 6.10 ? 472 ASP A CB 1 ATOM 3749 C CG . ASP A 1 472 ? 34.952 68.248 4.942 1.00 6.81 ? 472 ASP A CG 1 ATOM 3750 O OD1 . ASP A 1 472 ? 33.785 68.243 4.480 1.00 6.67 ? 472 ASP A OD1 1 ATOM 3751 O OD2 . ASP A 1 472 ? 35.311 67.670 6.007 1.00 6.86 ? 472 ASP A OD2 1 ATOM 3752 N N . GLY A 1 473 ? 38.005 68.565 1.135 1.00 6.15 ? 473 GLY A N 1 ATOM 3753 C CA . GLY A 1 473 ? 38.964 69.274 0.287 1.00 6.90 ? 473 GLY A CA 1 ATOM 3754 C C . GLY A 1 473 ? 38.413 69.375 -1.135 1.00 5.98 ? 473 GLY A C 1 ATOM 3755 O O . GLY A 1 473 ? 37.698 70.311 -1.475 1.00 5.77 ? 473 GLY A O 1 ATOM 3756 N N . ILE A 1 474 ? 38.734 68.363 -1.942 1.00 6.12 ? 474 ILE A N 1 ATOM 3757 C CA . ILE A 1 474 ? 38.297 68.362 -3.335 1.00 5.79 ? 474 ILE A CA 1 ATOM 3758 C C . ILE A 1 474 ? 36.793 68.463 -3.488 1.00 6.70 ? 474 ILE A C 1 ATOM 3759 O O . ILE A 1 474 ? 36.287 68.958 -4.527 1.00 7.65 ? 474 ILE A O 1 ATOM 3760 C CB . ILE A 1 474 ? 38.879 67.083 -4.045 1.00 5.54 ? 474 ILE A CB 1 ATOM 3761 C CG1 . ILE A 1 474 ? 38.615 67.149 -5.535 1.00 6.91 ? 474 ILE A CG1 1 ATOM 3762 C CG2 . ILE A 1 474 ? 38.336 65.770 -3.391 1.00 7.11 ? 474 ILE A CG2 1 ATOM 3763 C CD1 . ILE A 1 474 ? 39.380 66.016 -6.302 1.00 7.66 ? 474 ILE A CD1 1 ATOM 3764 N N . THR A 1 475 ? 36.048 68.028 -2.473 1.00 5.52 ? 475 THR A N 1 ATOM 3765 C CA . THR A 1 475 ? 34.574 68.105 -2.483 1.00 6.23 ? 475 THR A CA 1 ATOM 3766 C C . THR A 1 475 ? 34.059 69.569 -2.494 1.00 5.46 ? 475 THR A C 1 ATOM 3767 O O . THR A 1 475 ? 32.880 69.779 -2.812 1.00 5.96 ? 475 THR A O 1 ATOM 3768 C CB . THR A 1 475 ? 34.024 67.463 -1.218 1.00 6.23 ? 475 THR A CB 1 ATOM 3769 O OG1 . THR A 1 475 ? 34.578 68.213 -0.112 1.00 6.55 ? 475 THR A OG1 1 ATOM 3770 C CG2 . THR A 1 475 ? 34.355 65.989 -1.123 1.00 7.41 ? 475 THR A CG2 1 ATOM 3771 N N . GLY A 1 476 ? 34.878 70.562 -2.104 1.00 5.48 ? 476 GLY A N 1 ATOM 3772 C CA . GLY A 1 476 ? 34.366 71.917 -2.084 1.00 6.07 ? 476 GLY A CA 1 ATOM 3773 C C . GLY A 1 476 ? 33.384 72.168 -0.946 1.00 6.54 ? 476 GLY A C 1 ATOM 3774 O O . GLY A 1 476 ? 32.515 73.004 -1.086 1.00 6.88 ? 476 GLY A O 1 ATOM 3775 N N . THR A 1 477 ? 33.543 71.439 0.175 1.00 6.23 ? 477 THR A N 1 ATOM 3776 C CA . THR A 1 477 ? 32.629 71.562 1.291 1.00 6.33 ? 477 THR A CA 1 ATOM 3777 C C . THR A 1 477 ? 33.304 72.174 2.508 1.00 6.49 ? 477 THR A C 1 ATOM 3778 O O . THR A 1 477 ? 32.747 72.041 3.639 1.00 9.15 ? 477 THR A O 1 ATOM 3779 C CB . THR A 1 477 ? 31.972 70.208 1.650 1.00 6.19 ? 477 THR A CB 1 ATOM 3780 O OG1 . THR A 1 477 ? 32.988 69.219 1.930 1.00 7.25 ? 477 THR A OG1 1 ATOM 3781 C CG2 . THR A 1 477 ? 31.131 69.722 0.441 1.00 7.03 ? 477 THR A CG2 1 ATOM 3782 N N . ALA A 1 478 ? 34.405 72.906 2.374 1.00 6.45 ? 478 ALA A N 1 ATOM 3783 C CA . ALA A 1 478 ? 35.030 73.560 3.556 1.00 6.67 ? 478 ALA A CA 1 ATOM 3784 C C . ALA A 1 478 ? 34.713 75.046 3.606 1.00 7.05 ? 478 ALA A C 1 ATOM 3785 O O . ALA A 1 478 ? 34.213 75.691 2.664 1.00 7.86 ? 478 ALA A O 1 ATOM 3786 C CB . ALA A 1 478 ? 36.559 73.339 3.502 1.00 8.18 ? 478 ALA A CB 1 ATOM 3787 N N . LYS A 1 479 ? 34.961 75.658 4.764 1.00 6.88 ? 479 LYS A N 1 ATOM 3788 C CA . LYS A 1 479 ? 34.753 77.121 4.892 1.00 7.71 ? 479 LYS A CA 1 ATOM 3789 C C . LYS A 1 479 ? 35.709 77.827 3.949 1.00 7.46 ? 479 LYS A C 1 ATOM 3790 O O . LYS A 1 479 ? 36.803 77.338 3.623 1.00 7.37 ? 479 LYS A O 1 ATOM 3791 C CB . LYS A 1 479 ? 35.015 77.586 6.328 1.00 9.02 ? 479 LYS A CB 1 ATOM 3792 C CG . LYS A 1 479 ? 33.766 77.246 7.216 1.00 12.63 ? 479 LYS A CG 1 ATOM 3793 C CD . LYS A 1 479 ? 33.791 78.074 8.519 1.00 18.71 ? 479 LYS A CD 1 ATOM 3794 C CE . LYS A 1 479 ? 32.513 77.944 9.350 1.00 16.69 ? 479 LYS A CE 1 ATOM 3795 N NZ . LYS A 1 479 ? 31.242 78.531 8.778 1.00 17.13 ? 479 LYS A NZ 1 ATOM 3796 N N . THR A 1 480 ? 35.356 79.067 3.592 1.00 8.65 ? 480 THR A N 1 ATOM 3797 C CA . THR A 1 480 ? 36.178 79.830 2.664 1.00 8.45 ? 480 THR A CA 1 ATOM 3798 C C . THR A 1 480 ? 37.644 79.957 3.064 1.00 7.71 ? 480 THR A C 1 ATOM 3799 O O . THR A 1 480 ? 38.532 79.766 2.248 1.00 9.44 ? 480 THR A O 1 ATOM 3800 C CB . THR A 1 480 ? 35.604 81.237 2.488 1.00 11.21 ? 480 THR A CB 1 ATOM 3801 O OG1 . THR A 1 480 ? 34.282 81.117 1.966 1.00 14.17 ? 480 THR A OG1 1 ATOM 3802 C CG2 . THR A 1 480 ? 36.462 82.117 1.523 1.00 13.88 ? 480 THR A CG2 1 ATOM 3803 N N . HIS A 1 481 ? 37.948 80.239 4.353 1.00 8.75 ? 481 HIS A N 1 ATOM 3804 C CA . HIS A 1 481 ? 39.362 80.376 4.703 1.00 9.01 ? 481 HIS A CA 1 ATOM 3805 C C . HIS A 1 481 ? 40.122 79.063 4.647 1.00 8.35 ? 481 HIS A C 1 ATOM 3806 O O . HIS A 1 481 ? 41.321 79.057 4.472 1.00 9.52 ? 481 HIS A O 1 ATOM 3807 C CB . HIS A 1 481 ? 39.571 81.076 6.080 1.00 12.47 ? 481 HIS A CB 1 ATOM 3808 C CG . HIS A 1 481 ? 39.442 80.188 7.283 1.00 11.62 ? 481 HIS A CG 1 ATOM 3809 N ND1 . HIS A 1 481 ? 38.233 79.681 7.736 1.00 14.30 ? 481 HIS A ND1 1 ATOM 3810 C CD2 . HIS A 1 481 ? 40.393 79.707 8.121 1.00 10.56 ? 481 HIS A CD2 1 ATOM 3811 C CE1 . HIS A 1 481 ? 38.461 78.938 8.813 1.00 13.75 ? 481 HIS A CE1 1 ATOM 3812 N NE2 . HIS A 1 481 ? 39.766 78.939 9.058 1.00 11.89 ? 481 HIS A NE2 1 ATOM 3813 N N . VAL A 1 482 ? 39.401 77.941 4.750 1.00 8.23 ? 482 VAL A N 1 ATOM 3814 C CA . VAL A 1 482 ? 40.019 76.606 4.644 1.00 8.25 ? 482 VAL A CA 1 ATOM 3815 C C . VAL A 1 482 ? 40.292 76.287 3.172 1.00 6.07 ? 482 VAL A C 1 ATOM 3816 O O . VAL A 1 482 ? 41.353 75.778 2.849 1.00 7.50 ? 482 VAL A O 1 ATOM 3817 C CB . VAL A 1 482 ? 39.063 75.582 5.305 1.00 6.30 ? 482 VAL A CB 1 ATOM 3818 C CG1 . VAL A 1 482 ? 39.739 74.173 5.250 1.00 7.34 ? 482 VAL A CG1 1 ATOM 3819 C CG2 . VAL A 1 482 ? 38.867 75.916 6.818 1.00 8.06 ? 482 VAL A CG2 1 ATOM 3820 N N . VAL A 1 483 ? 39.350 76.612 2.296 1.00 6.77 ? 483 VAL A N 1 ATOM 3821 C CA . VAL A 1 483 ? 39.596 76.484 0.879 1.00 7.11 ? 483 VAL A CA 1 ATOM 3822 C C . VAL A 1 483 ? 40.838 77.284 0.476 1.00 6.76 ? 483 VAL A C 1 ATOM 3823 O O . VAL A 1 483 ? 41.683 76.786 -0.297 1.00 7.79 ? 483 VAL A O 1 ATOM 3824 C CB . VAL A 1 483 ? 38.364 76.992 0.044 1.00 7.19 ? 483 VAL A CB 1 ATOM 3825 C CG1 . VAL A 1 483 ? 38.662 76.979 -1.460 1.00 9.58 ? 483 VAL A CG1 1 ATOM 3826 C CG2 . VAL A 1 483 ? 37.135 76.087 0.345 1.00 9.25 ? 483 VAL A CG2 1 ATOM 3827 N N . VAL A 1 484 ? 40.984 78.507 1.027 1.00 8.38 ? 484 VAL A N 1 ATOM 3828 C CA . VAL A 1 484 ? 42.177 79.292 0.719 1.00 9.49 ? 484 VAL A CA 1 ATOM 3829 C C . VAL A 1 484 ? 43.448 78.589 1.193 1.00 9.82 ? 484 VAL A C 1 ATOM 3830 O O . VAL A 1 484 ? 44.460 78.579 0.451 1.00 9.08 ? 484 VAL A O 1 ATOM 3831 C CB . VAL A 1 484 ? 42.046 80.704 1.314 1.00 10.41 ? 484 VAL A CB 1 ATOM 3832 C CG1 . VAL A 1 484 ? 43.424 81.433 1.234 1.00 13.22 ? 484 VAL A CG1 1 ATOM 3833 C CG2 . VAL A 1 484 ? 40.935 81.469 0.577 1.00 14.05 ? 484 VAL A CG2 1 ATOM 3834 N N . ASP A 1 485 ? 43.406 77.960 2.367 1.00 8.30 ? 485 ASP A N 1 ATOM 3835 C CA . ASP A 1 485 ? 44.568 77.230 2.824 1.00 7.40 ? 485 ASP A CA 1 ATOM 3836 C C . ASP A 1 485 ? 44.919 76.072 1.882 1.00 7.74 ? 485 ASP A C 1 ATOM 3837 O O . ASP A 1 485 ? 46.098 75.854 1.588 1.00 7.55 ? 485 ASP A O 1 ATOM 3838 C CB . ASP A 1 485 ? 44.311 76.700 4.269 1.00 8.99 ? 485 ASP A CB 1 ATOM 3839 C CG . ASP A 1 485 ? 45.550 76.070 4.889 1.00 9.52 ? 485 ASP A CG 1 ATOM 3840 O OD1 . ASP A 1 485 ? 46.565 76.794 4.988 1.00 14.12 ? 485 ASP A OD1 1 ATOM 3841 O OD2 . ASP A 1 485 ? 45.525 74.912 5.256 1.00 10.13 ? 485 ASP A OD2 1 ATOM 3842 N N . TYR A 1 486 ? 43.917 75.301 1.465 1.00 7.25 ? 486 TYR A N 1 ATOM 3843 C CA . TYR A 1 486 ? 44.200 74.208 0.518 1.00 6.44 ? 486 TYR A CA 1 ATOM 3844 C C . TYR A 1 486 ? 44.782 74.770 -0.778 1.00 7.49 ? 486 TYR A C 1 ATOM 3845 O O . TYR A 1 486 ? 45.699 74.147 -1.340 1.00 7.68 ? 486 TYR A O 1 ATOM 3846 C CB . TYR A 1 486 ? 42.937 73.416 0.155 1.00 7.64 ? 486 TYR A CB 1 ATOM 3847 C CG . TYR A 1 486 ? 42.332 72.560 1.283 1.00 7.07 ? 486 TYR A CG 1 ATOM 3848 C CD1 . TYR A 1 486 ? 43.139 71.688 2.055 1.00 10.01 ? 486 TYR A CD1 1 ATOM 3849 C CD2 . TYR A 1 486 ? 40.970 72.600 1.503 1.00 7.12 ? 486 TYR A CD2 1 ATOM 3850 C CE1 . TYR A 1 486 ? 42.528 70.873 3.046 1.00 8.94 ? 486 TYR A CE1 1 ATOM 3851 C CE2 . TYR A 1 486 ? 40.343 71.780 2.489 1.00 7.62 ? 486 TYR A CE2 1 ATOM 3852 C CZ . TYR A 1 486 ? 41.144 70.959 3.217 1.00 8.01 ? 486 TYR A CZ 1 ATOM 3853 O OH . TYR A 1 486 ? 40.528 70.140 4.178 1.00 9.33 ? 486 TYR A OH 1 ATOM 3854 N N . GLU A 1 487 ? 44.252 75.908 -1.262 1.00 7.01 ? 487 GLU A N 1 ATOM 3855 C CA . GLU A 1 487 ? 44.751 76.473 -2.508 1.00 8.23 ? 487 GLU A CA 1 ATOM 3856 C C . GLU A 1 487 ? 46.231 76.887 -2.347 1.00 9.05 ? 487 GLU A C 1 ATOM 3857 O O . GLU A 1 487 ? 47.070 76.624 -3.232 1.00 8.91 ? 487 GLU A O 1 ATOM 3858 C CB . GLU A 1 487 ? 43.903 77.682 -2.910 1.00 8.61 ? 487 GLU A CB 1 ATOM 3859 C CG . GLU A 1 487 ? 44.292 78.205 -4.306 1.00 10.08 ? 487 GLU A CG 1 ATOM 3860 C CD . GLU A 1 487 ? 43.440 79.366 -4.773 1.00 16.70 ? 487 GLU A CD 1 ATOM 3861 O OE1 . GLU A 1 487 ? 42.317 79.549 -4.297 1.00 16.65 ? 487 GLU A OE1 1 ATOM 3862 O OE2 . GLU A 1 487 ? 43.947 80.118 -5.644 1.00 18.84 ? 487 GLU A OE2 1 ATOM 3863 N N . GLN A 1 488 ? 46.535 77.541 -1.237 1.00 8.01 ? 488 GLN A N 1 ATOM 3864 C CA . GLN A 1 488 ? 47.917 77.970 -0.946 1.00 8.40 ? 488 GLN A CA 1 ATOM 3865 C C . GLN A 1 488 ? 48.859 76.777 -0.903 1.00 8.15 ? 488 GLN A C 1 ATOM 3866 O O . GLN A 1 488 ? 49.927 76.825 -1.476 1.00 9.24 ? 488 GLN A O 1 ATOM 3867 C CB . GLN A 1 488 ? 47.991 78.704 0.398 1.00 11.70 ? 488 GLN A CB 1 ATOM 3868 C CG . GLN A 1 488 ? 47.356 80.069 0.436 1.00 23.14 ? 488 GLN A CG 1 ATOM 3869 C CD . GLN A 1 488 ? 47.483 80.721 1.808 1.00 29.84 ? 488 GLN A CD 1 ATOM 3870 O OE1 . GLN A 1 488 ? 47.712 80.050 2.815 1.00 41.29 ? 488 GLN A OE1 1 ATOM 3871 N NE2 . GLN A 1 488 ? 47.316 82.031 1.848 1.00 37.06 ? 488 GLN A NE2 1 ATOM 3872 N N . ARG A 1 489 ? 48.446 75.704 -0.234 1.00 6.71 ? 489 ARG A N 1 ATOM 3873 C CA . ARG A 1 489 ? 49.260 74.495 -0.135 1.00 7.79 ? 489 ARG A CA 1 ATOM 3874 C C . ARG A 1 489 ? 49.469 73.897 -1.528 1.00 7.74 ? 489 ARG A C 1 ATOM 3875 O O . ARG A 1 489 ? 50.584 73.502 -1.880 1.00 7.13 ? 489 ARG A O 1 ATOM 3876 C CB . ARG A 1 489 ? 48.547 73.495 0.787 1.00 7.30 ? 489 ARG A CB 1 ATOM 3877 C CG . ARG A 1 489 ? 48.651 73.896 2.222 1.00 8.44 ? 489 ARG A CG 1 ATOM 3878 C CD . ARG A 1 489 ? 47.676 72.977 3.024 1.00 10.80 ? 489 ARG A CD 1 ATOM 3879 N NE . ARG A 1 489 ? 47.753 73.140 4.498 1.00 10.03 ? 489 ARG A NE 1 ATOM 3880 C CZ . ARG A 1 489 ? 48.624 72.494 5.268 1.00 12.05 ? 489 ARG A CZ 1 ATOM 3881 N NH1 . ARG A 1 489 ? 49.509 71.639 4.780 1.00 13.53 ? 489 ARG A NH1 1 ATOM 3882 N NH2 . ARG A 1 489 ? 48.601 72.709 6.590 1.00 12.14 ? 489 ARG A NH2 1 ATOM 3883 N N . MET A 1 490 ? 48.411 73.829 -2.353 1.00 7.60 ? 490 MET A N 1 ATOM 3884 C CA . MET A 1 490 ? 48.588 73.292 -3.693 1.00 7.16 ? 490 MET A CA 1 ATOM 3885 C C . MET A 1 490 ? 49.469 74.187 -4.580 1.00 7.42 ? 490 MET A C 1 ATOM 3886 O O . MET A 1 490 ? 50.199 73.674 -5.428 1.00 7.96 ? 490 MET A O 1 ATOM 3887 C CB . MET A 1 490 ? 47.242 73.013 -4.390 1.00 7.90 ? 490 MET A CB 1 ATOM 3888 C CG . MET A 1 490 ? 46.529 71.837 -3.701 1.00 8.55 ? 490 MET A CG 1 ATOM 3889 S SD . MET A 1 490 ? 45.175 71.147 -4.810 1.00 11.20 ? 490 MET A SD 1 ATOM 3890 C CE . MET A 1 490 ? 43.882 72.365 -4.456 1.00 13.23 ? 490 MET A CE 1 ATOM 3891 N N . GLN A 1 491 ? 49.409 75.504 -4.401 1.00 7.09 ? 491 GLN A N 1 ATOM 3892 C CA . GLN A 1 491 ? 50.290 76.397 -5.170 1.00 7.90 ? 491 GLN A CA 1 ATOM 3893 C C . GLN A 1 491 ? 51.747 76.142 -4.817 1.00 8.10 ? 491 GLN A C 1 ATOM 3894 O O . GLN A 1 491 ? 52.625 76.079 -5.690 1.00 9.13 ? 491 GLN A O 1 ATOM 3895 C CB . GLN A 1 491 ? 49.959 77.865 -4.859 1.00 10.56 ? 491 GLN A CB 1 ATOM 3896 C CG . GLN A 1 491 ? 50.784 78.779 -5.774 1.00 17.24 ? 491 GLN A CG 1 ATOM 3897 C CD . GLN A 1 491 ? 50.568 78.486 -7.264 1.00 28.37 ? 491 GLN A CD 1 ATOM 3898 O OE1 . GLN A 1 491 ? 49.445 78.338 -7.696 1.00 32.73 ? 491 GLN A OE1 1 ATOM 3899 N NE2 . GLN A 1 491 ? 51.654 78.381 -8.038 1.00 35.86 ? 491 GLN A NE2 1 ATOM 3900 N N . GLU A 1 492 ? 52.038 75.952 -3.527 1.00 8.04 ? 492 GLU A N 1 ATOM 3901 C CA . GLU A 1 492 ? 53.405 75.630 -3.130 1.00 8.68 ? 492 GLU A CA 1 ATOM 3902 C C . GLU A 1 492 ? 53.800 74.280 -3.715 1.00 8.61 ? 492 GLU A C 1 ATOM 3903 O O . GLU A 1 492 ? 54.945 74.101 -4.143 1.00 9.60 ? 492 GLU A O 1 ATOM 3904 C CB . GLU A 1 492 ? 53.520 75.565 -1.596 1.00 11.70 ? 492 GLU A CB 1 ATOM 3905 C CG . GLU A 1 492 ? 53.445 76.984 -0.923 1.00 17.17 ? 492 GLU A CG 1 ATOM 3906 C CD . GLU A 1 492 ? 54.425 78.010 -1.555 1.00 24.87 ? 492 GLU A CD 1 ATOM 3907 O OE1 . GLU A 1 492 ? 55.681 77.783 -1.548 1.00 28.14 ? 492 GLU A OE1 1 ATOM 3908 O OE2 . GLU A 1 492 ? 53.933 79.051 -2.066 1.00 28.14 ? 492 GLU A OE2 1 ATOM 3909 N N . ALA A 1 493 ? 52.870 73.313 -3.728 1.00 7.60 ? 493 ALA A N 1 ATOM 3910 C CA . ALA A 1 493 ? 53.182 72.018 -4.322 1.00 6.04 ? 493 ALA A CA 1 ATOM 3911 C C . ALA A 1 493 ? 53.499 72.163 -5.828 1.00 6.97 ? 493 ALA A C 1 ATOM 3912 O O . ALA A 1 493 ? 54.401 71.490 -6.338 1.00 6.96 ? 493 ALA A O 1 ATOM 3913 C CB . ALA A 1 493 ? 51.998 71.077 -4.083 1.00 6.80 ? 493 ALA A CB 1 ATOM 3914 N N . LEU A 1 494 ? 52.725 72.976 -6.564 1.00 6.42 ? 494 LEU A N 1 ATOM 3915 C CA . LEU A 1 494 ? 53.016 73.181 -7.988 1.00 7.36 ? 494 LEU A CA 1 ATOM 3916 C C . LEU A 1 494 ? 54.405 73.790 -8.158 1.00 7.41 ? 494 LEU A C 1 ATOM 3917 O O . LEU A 1 494 ? 55.137 73.369 -9.076 1.00 8.06 ? 494 LEU A O 1 ATOM 3918 C CB . LEU A 1 494 ? 51.953 74.097 -8.610 1.00 8.23 ? 494 LEU A CB 1 ATOM 3919 C CG . LEU A 1 494 ? 50.602 73.428 -8.808 1.00 8.08 ? 494 LEU A CG 1 ATOM 3920 C CD1 . LEU A 1 494 ? 49.583 74.555 -9.142 1.00 10.10 ? 494 LEU A CD1 1 ATOM 3921 C CD2 . LEU A 1 494 ? 50.639 72.383 -9.929 1.00 9.24 ? 494 LEU A CD2 1 ATOM 3922 N N . LYS A 1 495 ? 54.790 74.754 -7.322 1.00 7.93 ? 495 LYS A N 1 ATOM 3923 C CA . LYS A 1 495 ? 56.145 75.362 -7.420 1.00 7.87 ? 495 LYS A CA 1 ATOM 3924 C C . LYS A 1 495 ? 57.206 74.296 -7.121 1.00 8.14 ? 495 LYS A C 1 ATOM 3925 O O . LYS A 1 495 ? 58.266 74.249 -7.795 1.00 7.92 ? 495 LYS A O 1 ATOM 3926 C CB . LYS A 1 495 ? 56.288 76.523 -6.419 1.00 11.18 ? 495 LYS A CB 1 ATOM 3927 C CG . LYS A 1 495 ? 55.429 77.702 -6.834 1.00 15.00 ? 495 LYS A CG 1 ATOM 3928 C CD . LYS A 1 495 ? 55.600 78.931 -5.970 1.00 23.45 ? 495 LYS A CD 1 ATOM 3929 C CE . LYS A 1 495 ? 55.254 78.733 -4.545 1.00 28.89 ? 495 LYS A CE 1 ATOM 3930 N NZ . LYS A 1 495 ? 55.562 80.037 -3.795 1.00 35.29 ? 495 LYS A NZ 1 ATOM 3931 N N . ALA A 1 496 ? 56.981 73.430 -6.147 1.00 6.35 ? 496 ALA A N 1 ATOM 3932 C CA . ALA A 1 496 ? 57.907 72.330 -5.887 1.00 7.04 ? 496 ALA A CA 1 ATOM 3933 C C . ALA A 1 496 ? 58.073 71.398 -7.082 1.00 6.92 ? 496 ALA A C 1 ATOM 3934 O O . ALA A 1 496 ? 59.164 71.018 -7.421 1.00 7.19 ? 496 ALA A O 1 ATOM 3935 C CB . ALA A 1 496 ? 57.446 71.539 -4.669 1.00 7.80 ? 496 ALA A CB 1 ATOM 3936 N N . CYS A 1 497 ? 56.965 71.026 -7.711 1.00 5.94 ? 497 CYS A N 1 ATOM 3937 C CA . CYS A 1 497 ? 56.997 70.164 -8.899 1.00 7.42 ? 497 CYS A CA 1 ATOM 3938 C C . CYS A 1 497 ? 57.761 70.852 -10.037 1.00 7.12 ? 497 CYS A C 1 ATOM 3939 O O . CYS A 1 497 ? 58.582 70.220 -10.693 1.00 6.89 ? 497 CYS A O 1 ATOM 3940 C CB . CYS A 1 497 ? 55.577 69.832 -9.378 1.00 6.91 ? 497 CYS A CB 1 ATOM 3941 S SG . CYS A 1 497 ? 54.711 68.685 -8.306 1.00 8.45 ? 497 CYS A SG 1 ATOM 3942 N N . GLN A 1 498 ? 57.524 72.135 -10.249 1.00 6.59 ? 498 GLN A N 1 ATOM 3943 C CA . GLN A 1 498 ? 58.230 72.866 -11.295 1.00 6.75 ? 498 GLN A CA 1 ATOM 3944 C C . GLN A 1 498 ? 59.733 72.831 -11.048 1.00 7.06 ? 498 GLN A C 1 ATOM 3945 O O . GLN A 1 498 ? 60.498 72.566 -11.969 1.00 8.17 ? 498 GLN A O 1 ATOM 3946 C CB . GLN A 1 498 ? 57.756 74.317 -11.400 1.00 7.69 ? 498 GLN A CB 1 ATOM 3947 C CG . GLN A 1 498 ? 58.593 75.111 -12.393 1.00 12.75 ? 498 GLN A CG 1 ATOM 3948 C CD . GLN A 1 498 ? 58.136 76.533 -12.579 1.00 14.67 ? 498 GLN A CD 1 ATOM 3949 O OE1 . GLN A 1 498 ? 57.878 76.975 -13.694 1.00 18.66 ? 498 GLN A OE1 1 ATOM 3950 N NE2 . GLN A 1 498 ? 58.067 77.274 -11.483 1.00 13.61 ? 498 GLN A NE2 1 ATOM 3951 N N . MET A 1 499 ? 60.150 73.094 -9.810 1.00 6.94 ? 499 MET A N 1 ATOM 3952 C CA . MET A 1 499 ? 61.568 73.089 -9.516 1.00 8.31 ? 499 MET A CA 1 ATOM 3953 C C . MET A 1 499 ? 62.200 71.753 -9.842 1.00 7.29 ? 499 MET A C 1 ATOM 3954 O O . MET A 1 499 ? 63.244 71.672 -10.495 1.00 8.16 ? 499 MET A O 1 ATOM 3955 C CB . MET A 1 499 ? 61.760 73.440 -8.032 1.00 8.90 ? 499 MET A CB 1 ATOM 3956 C CG . MET A 1 499 ? 63.213 73.295 -7.504 1.00 11.52 ? 499 MET A CG 1 ATOM 3957 S SD . MET A 1 499 ? 64.520 74.214 -8.381 1.00 16.37 ? 499 MET A SD 1 ATOM 3958 C CE . MET A 1 499 ? 63.844 75.723 -7.867 1.00 15.04 ? 499 MET A CE 1 ATOM 3959 N N . VAL A 1 500 ? 61.588 70.659 -9.383 1.00 7.10 ? 500 VAL A N 1 ATOM 3960 C CA . VAL A 1 500 ? 62.131 69.341 -9.602 1.00 5.81 ? 500 VAL A CA 1 ATOM 3961 C C . VAL A 1 500 ? 62.127 69.011 -11.089 1.00 6.76 ? 500 VAL A C 1 ATOM 3962 O O . VAL A 1 500 ? 63.131 68.471 -11.614 1.00 6.90 ? 500 VAL A O 1 ATOM 3963 C CB . VAL A 1 500 ? 61.316 68.297 -8.815 1.00 6.85 ? 500 VAL A CB 1 ATOM 3964 C CG1 . VAL A 1 500 ? 61.753 66.869 -9.222 1.00 7.79 ? 500 VAL A CG1 1 ATOM 3965 C CG2 . VAL A 1 500 ? 61.559 68.507 -7.298 1.00 8.21 ? 500 VAL A CG2 1 ATOM 3966 N N . MET A 1 501 ? 61.032 69.305 -11.792 1.00 6.50 ? 501 MET A N 1 ATOM 3967 C CA . MET A 1 501 ? 60.970 69.012 -13.226 1.00 7.13 ? 501 MET A CA 1 ATOM 3968 C C . MET A 1 501 ? 62.066 69.760 -13.985 1.00 7.59 ? 501 MET A C 1 ATOM 3969 O O . MET A 1 501 ? 62.711 69.143 -14.831 1.00 7.29 ? 501 MET A O 1 ATOM 3970 C CB . MET A 1 501 ? 59.604 69.432 -13.773 1.00 7.32 ? 501 MET A CB 1 ATOM 3971 C CG . MET A 1 501 ? 58.494 68.495 -13.276 1.00 7.66 ? 501 MET A CG 1 ATOM 3972 S SD . MET A 1 501 ? 56.802 69.143 -13.535 1.00 12.49 ? 501 MET A SD 1 ATOM 3973 C CE . MET A 1 501 ? 56.758 68.863 -15.238 1.00 14.05 ? 501 MET A CE 1 ATOM 3974 N N . GLN A 1 502 ? 62.239 71.062 -13.733 1.00 7.60 ? 502 GLN A N 1 ATOM 3975 C CA . GLN A 1 502 ? 63.201 71.824 -14.552 1.00 6.91 ? 502 GLN A CA 1 ATOM 3976 C C . GLN A 1 502 ? 64.631 71.444 -14.222 1.00 9.09 ? 502 GLN A C 1 ATOM 3977 O O . GLN A 1 502 ? 65.454 71.368 -15.149 1.00 8.37 ? 502 GLN A O 1 ATOM 3978 C CB . GLN A 1 502 ? 62.919 73.320 -14.446 1.00 9.08 ? 502 GLN A CB 1 ATOM 3979 C CG . GLN A 1 502 ? 63.135 73.937 -13.080 1.00 9.35 ? 502 GLN A CG 1 ATOM 3980 C CD . GLN A 1 502 ? 64.560 74.443 -12.885 1.00 12.45 ? 502 GLN A CD 1 ATOM 3981 O OE1 . GLN A 1 502 ? 65.341 74.577 -13.861 1.00 10.91 ? 502 GLN A OE1 1 ATOM 3982 N NE2 . GLN A 1 502 ? 64.923 74.738 -11.638 1.00 11.83 ? 502 GLN A NE2 1 ATOM 3983 N N . GLN A 1 503 ? 64.949 71.112 -12.959 1.00 7.18 ? 503 GLN A N 1 ATOM 3984 C CA . GLN A 1 503 ? 66.300 70.610 -12.681 1.00 8.14 ? 503 GLN A CA 1 ATOM 3985 C C . GLN A 1 503 ? 66.507 69.291 -13.415 1.00 8.14 ? 503 GLN A C 1 ATOM 3986 O O . GLN A 1 503 ? 67.619 69.000 -13.930 1.00 8.47 ? 503 GLN A O 1 ATOM 3987 C CB . GLN A 1 503 ? 66.507 70.347 -11.170 1.00 9.11 ? 503 GLN A CB 1 ATOM 3988 C CG . GLN A 1 503 ? 66.611 71.632 -10.340 1.00 11.09 ? 503 GLN A CG 1 ATOM 3989 C CD . GLN A 1 503 ? 67.991 72.299 -10.481 1.00 11.39 ? 503 GLN A CD 1 ATOM 3990 O OE1 . GLN A 1 503 ? 68.973 71.653 -10.796 1.00 13.42 ? 503 GLN A OE1 1 ATOM 3991 N NE2 . GLN A 1 503 ? 68.062 73.593 -10.196 1.00 13.01 ? 503 GLN A NE2 1 ATOM 3992 N N . SER A 1 504 ? 65.467 68.439 -13.505 1.00 6.61 ? 504 SER A N 1 ATOM 3993 C CA . SER A 1 504 ? 65.627 67.128 -14.131 1.00 6.83 ? 504 SER A CA 1 ATOM 3994 C C . SER A 1 504 ? 65.819 67.265 -15.648 1.00 7.91 ? 504 SER A C 1 ATOM 3995 O O . SER A 1 504 ? 66.655 66.552 -16.229 1.00 7.46 ? 504 SER A O 1 ATOM 3996 C CB . SER A 1 504 ? 64.364 66.253 -13.869 1.00 7.70 ? 504 SER A CB 1 ATOM 3997 O OG . SER A 1 504 ? 64.222 65.982 -12.461 1.00 8.31 ? 504 SER A OG 1 ATOM 3998 N N . VAL A 1 505 ? 65.066 68.164 -16.291 1.00 6.57 ? 505 VAL A N 1 ATOM 3999 C CA . VAL A 1 505 ? 65.221 68.384 -17.738 1.00 7.95 ? 505 VAL A CA 1 ATOM 4000 C C . VAL A 1 505 ? 66.657 68.883 -18.027 1.00 7.52 ? 505 VAL A C 1 ATOM 4001 O O . VAL A 1 505 ? 67.316 68.398 -18.981 1.00 8.58 ? 505 VAL A O 1 ATOM 4002 C CB . VAL A 1 505 ? 64.178 69.400 -18.240 1.00 7.97 ? 505 VAL A CB 1 ATOM 4003 C CG1 . VAL A 1 505 ? 64.533 69.873 -19.658 1.00 10.16 ? 505 VAL A CG1 1 ATOM 4004 C CG2 . VAL A 1 505 ? 62.750 68.800 -18.182 1.00 9.92 ? 505 VAL A CG2 1 ATOM 4005 N N . TYR A 1 506 ? 67.148 69.817 -17.232 1.00 7.69 ? 506 TYR A N 1 ATOM 4006 C CA . TYR A 1 506 ? 68.518 70.301 -17.448 1.00 8.29 ? 506 TYR A CA 1 ATOM 4007 C C . TYR A 1 506 ? 69.539 69.135 -17.359 1.00 9.12 ? 506 TYR A C 1 ATOM 4008 O O . TYR A 1 506 ? 70.426 69.015 -18.183 1.00 9.83 ? 506 TYR A O 1 ATOM 4009 C CB . TYR A 1 506 ? 68.846 71.475 -16.498 1.00 8.28 ? 506 TYR A CB 1 ATOM 4010 C CG . TYR A 1 506 ? 70.288 71.968 -16.605 1.00 9.31 ? 506 TYR A CG 1 ATOM 4011 C CD1 . TYR A 1 506 ? 70.822 72.398 -17.814 1.00 13.77 ? 506 TYR A CD1 1 ATOM 4012 C CD2 . TYR A 1 506 ? 71.116 71.967 -15.492 1.00 10.36 ? 506 TYR A CD2 1 ATOM 4013 C CE1 . TYR A 1 506 ? 72.159 72.828 -17.905 1.00 12.54 ? 506 TYR A CE1 1 ATOM 4014 C CE2 . TYR A 1 506 ? 72.470 72.392 -15.579 1.00 14.39 ? 506 TYR A CE2 1 ATOM 4015 C CZ . TYR A 1 506 ? 72.964 72.813 -16.785 1.00 11.88 ? 506 TYR A CZ 1 ATOM 4016 O OH . TYR A 1 506 ? 74.292 73.216 -16.892 1.00 14.51 ? 506 TYR A OH 1 ATOM 4017 N N . ARG A 1 507 ? 69.389 68.263 -16.385 1.00 8.45 ? 507 ARG A N 1 ATOM 4018 C CA . ARG A 1 507 ? 70.293 67.128 -16.272 1.00 7.85 ? 507 ARG A CA 1 ATOM 4019 C C . ARG A 1 507 ? 70.141 66.115 -17.408 1.00 9.39 ? 507 ARG A C 1 ATOM 4020 O O . ARG A 1 507 ? 71.102 65.578 -17.900 1.00 9.59 ? 507 ARG A O 1 ATOM 4021 C CB . ARG A 1 507 ? 70.096 66.452 -14.920 1.00 9.11 ? 507 ARG A CB 1 ATOM 4022 C CG . ARG A 1 507 ? 71.213 65.463 -14.578 1.00 11.12 ? 507 ARG A CG 1 ATOM 4023 C CD . ARG A 1 507 ? 71.091 65.013 -13.149 1.00 11.50 ? 507 ARG A CD 1 ATOM 4024 N NE . ARG A 1 507 ? 72.081 63.991 -12.795 1.00 14.04 ? 507 ARG A NE 1 ATOM 4025 C CZ . ARG A 1 507 ? 72.138 63.412 -11.602 1.00 12.82 ? 507 ARG A CZ 1 ATOM 4026 N NH1 . ARG A 1 507 ? 71.307 63.765 -10.656 1.00 14.89 ? 507 ARG A NH1 1 ATOM 4027 N NH2 . ARG A 1 507 ? 73.043 62.488 -11.348 1.00 18.98 ? 507 ARG A NH2 1 ATOM 4028 N N . LEU A 1 508 ? 68.913 65.841 -17.806 1.00 7.71 ? 508 LEU A N 1 ATOM 4029 C CA . LEU A 1 508 ? 68.676 64.837 -18.826 1.00 7.96 ? 508 LEU A CA 1 ATOM 4030 C C . LEU A 1 508 ? 69.075 65.243 -20.235 1.00 7.25 ? 508 LEU A C 1 ATOM 4031 O O . LEU A 1 508 ? 69.289 64.357 -21.082 1.00 9.94 ? 508 LEU A O 1 ATOM 4032 C CB . LEU A 1 508 ? 67.168 64.475 -18.845 1.00 7.42 ? 508 LEU A CB 1 ATOM 4033 C CG . LEU A 1 508 ? 66.740 63.599 -17.612 1.00 7.50 ? 508 LEU A CG 1 ATOM 4034 C CD1 . LEU A 1 508 ? 65.204 63.676 -17.500 1.00 8.53 ? 508 LEU A CD1 1 ATOM 4035 C CD2 . LEU A 1 508 ? 67.182 62.153 -17.759 1.00 9.67 ? 508 LEU A CD2 1 ATOM 4036 N N . LEU A 1 509 ? 69.164 66.546 -20.502 1.00 7.87 ? 509 LEU A N 1 ATOM 4037 C CA . LEU A 1 509 ? 69.434 67.039 -21.855 1.00 8.19 ? 509 LEU A CA 1 ATOM 4038 C C . LEU A 1 509 ? 70.707 67.829 -21.967 1.00 8.05 ? 509 LEU A C 1 ATOM 4039 O O . LEU A 1 509 ? 70.872 68.565 -22.956 1.00 10.08 ? 509 LEU A O 1 ATOM 4040 C CB . LEU A 1 509 ? 68.198 67.844 -22.372 1.00 8.17 ? 509 LEU A CB 1 ATOM 4041 C CG . LEU A 1 509 ? 66.981 66.976 -22.671 1.00 7.67 ? 509 LEU A CG 1 ATOM 4042 C CD1 . LEU A 1 509 ? 65.857 67.956 -23.087 1.00 7.40 ? 509 LEU A CD1 1 ATOM 4043 C CD2 . LEU A 1 509 ? 67.234 65.967 -23.783 1.00 10.20 ? 509 LEU A CD2 1 ATOM 4044 N N . THR A 1 510 ? 71.625 67.746 -20.999 1.00 8.13 ? 510 THR A N 1 ATOM 4045 C CA . THR A 1 510 ? 72.906 68.468 -21.137 1.00 8.16 ? 510 THR A CA 1 ATOM 4046 C C . THR A 1 510 ? 74.037 67.429 -21.146 1.00 9.39 ? 510 THR A C 1 ATOM 4047 O O . THR A 1 510 ? 74.016 66.472 -20.364 1.00 10.15 ? 510 THR A O 1 ATOM 4048 C CB . THR A 1 510 ? 73.076 69.425 -19.964 1.00 9.14 ? 510 THR A CB 1 ATOM 4049 O OG1 . THR A 1 510 ? 71.960 70.353 -19.957 1.00 9.88 ? 510 THR A OG1 1 ATOM 4050 C CG2 . THR A 1 510 ? 74.383 70.283 -20.081 1.00 10.02 ? 510 THR A CG2 1 ATOM 4051 N N . LYS A 1 511 ? 75.027 67.651 -22.017 1.00 9.71 ? 511 LYS A N 1 ATOM 4052 C CA . LYS A 1 511 ? 76.202 66.741 -22.085 1.00 10.90 ? 511 LYS A CA 1 ATOM 4053 C C . LYS A 1 511 ? 76.699 66.615 -20.662 1.00 10.80 ? 511 LYS A C 1 ATOM 4054 O O . LYS A 1 511 ? 76.963 67.601 -19.979 1.00 9.71 ? 511 LYS A O 1 ATOM 4055 C CB . LYS A 1 511 ? 77.239 67.384 -22.999 1.00 13.62 ? 511 LYS A CB 1 ATOM 4056 C CG . LYS A 1 511 ? 78.431 66.414 -23.153 1.00 18.99 ? 511 LYS A CG 1 ATOM 4057 C CD . LYS A 1 511 ? 79.568 66.883 -24.055 1.00 21.46 ? 511 LYS A CD 1 ATOM 4058 C CE . LYS A 1 511 ? 80.717 65.782 -24.047 1.00 25.01 ? 511 LYS A CE 1 ATOM 4059 N NZ . LYS A 1 511 ? 81.991 66.051 -24.822 1.00 30.19 ? 511 LYS A NZ 1 ATOM 4060 N N . PRO A 1 512 ? 76.941 65.361 -20.193 1.00 11.35 ? 512 PRO A N 1 ATOM 4061 C CA . PRO A 1 512 ? 77.351 65.206 -18.789 1.00 12.18 ? 512 PRO A CA 1 ATOM 4062 C C . PRO A 1 512 ? 78.582 65.933 -18.300 1.00 11.32 ? 512 PRO A C 1 ATOM 4063 O O . PRO A 1 512 ? 78.608 66.416 -17.174 1.00 13.07 ? 512 PRO A O 1 ATOM 4064 C CB . PRO A 1 512 ? 77.477 63.695 -18.621 1.00 15.14 ? 512 PRO A CB 1 ATOM 4065 C CG . PRO A 1 512 ? 76.482 63.169 -19.617 1.00 19.04 ? 512 PRO A CG 1 ATOM 4066 C CD . PRO A 1 512 ? 76.562 64.064 -20.809 1.00 14.65 ? 512 PRO A CD 1 ATOM 4067 N N . SER A 1 513 ? 79.568 66.032 -19.177 1.00 11.37 ? 513 SER A N 1 ATOM 4068 C CA . SER A 1 513 ? 80.825 66.730 -18.789 1.00 11.41 ? 513 SER A CA 1 ATOM 4069 C C . SER A 1 513 ? 80.678 68.239 -18.800 1.00 11.42 ? 513 SER A C 1 ATOM 4070 O O . SER A 1 513 ? 81.610 68.951 -18.411 1.00 13.32 ? 513 SER A O 1 ATOM 4071 C CB . SER A 1 513 ? 81.987 66.292 -19.725 1.00 12.06 ? 513 SER A CB 1 ATOM 4072 O OG . SER A 1 513 ? 81.675 66.635 -21.052 1.00 13.29 ? 513 SER A OG 1 ATOM 4073 N N . ILE A 1 514 ? 79.525 68.763 -19.251 1.00 11.28 ? 514 ILE A N 1 ATOM 4074 C CA . ILE A 1 514 ? 79.242 70.192 -19.282 1.00 11.78 ? 514 ILE A CA 1 ATOM 4075 C C . ILE A 1 514 ? 78.233 70.559 -18.178 1.00 11.28 ? 514 ILE A C 1 ATOM 4076 O O . ILE A 1 514 ? 78.294 71.635 -17.647 1.00 12.59 ? 514 ILE A O 1 ATOM 4077 C CB . ILE A 1 514 ? 78.680 70.599 -20.711 1.00 13.20 ? 514 ILE A CB 1 ATOM 4078 C CG1 . ILE A 1 514 ? 79.816 70.520 -21.741 1.00 17.17 ? 514 ILE A CG1 1 ATOM 4079 C CG2 . ILE A 1 514 ? 78.033 71.980 -20.643 1.00 15.58 ? 514 ILE A CG2 1 ATOM 4080 C CD1 . ILE A 1 514 ? 79.356 70.742 -23.191 1.00 21.73 ? 514 ILE A CD1 1 ATOM 4081 N N . TYR A 1 515 ? 77.358 69.616 -17.801 1.00 10.92 ? 515 TYR A N 1 ATOM 4082 C CA . TYR A 1 515 ? 76.315 69.825 -16.779 1.00 9.98 ? 515 TYR A CA 1 ATOM 4083 C C . TYR A 1 515 ? 76.902 70.458 -15.531 1.00 10.48 ? 515 TYR A C 1 ATOM 4084 O O . TYR A 1 515 ? 77.789 69.853 -14.897 1.00 11.87 ? 515 TYR A O 1 ATOM 4085 C CB . TYR A 1 515 ? 75.711 68.456 -16.518 1.00 11.13 ? 515 TYR A CB 1 ATOM 4086 C CG . TYR A 1 515 ? 74.709 68.414 -15.416 1.00 11.16 ? 515 TYR A CG 1 ATOM 4087 C CD1 . TYR A 1 515 ? 73.532 69.144 -15.465 1.00 9.78 ? 515 TYR A CD1 1 ATOM 4088 C CD2 . TYR A 1 515 ? 74.951 67.613 -14.324 1.00 10.68 ? 515 TYR A CD2 1 ATOM 4089 C CE1 . TYR A 1 515 ? 72.576 69.072 -14.399 1.00 9.06 ? 515 TYR A CE1 1 ATOM 4090 C CE2 . TYR A 1 515 ? 74.023 67.514 -13.253 1.00 10.43 ? 515 TYR A CE2 1 ATOM 4091 C CZ . TYR A 1 515 ? 72.865 68.249 -13.318 1.00 11.34 ? 515 TYR A CZ 1 ATOM 4092 O OH . TYR A 1 515 ? 71.965 68.168 -12.278 1.00 10.85 ? 515 TYR A OH 1 ATOM 4093 N N . SER A 1 516 ? 76.399 71.618 -15.143 1.00 11.37 ? 516 SER A N 1 ATOM 4094 C CA . SER A 1 516 ? 76.938 72.329 -13.996 1.00 12.33 ? 516 SER A CA 1 ATOM 4095 C C . SER A 1 516 ? 75.815 72.910 -13.158 1.00 14.52 ? 516 SER A C 1 ATOM 4096 O O . SER A 1 516 ? 75.546 74.098 -13.236 1.00 14.91 ? 516 SER A O 1 ATOM 4097 C CB . SER A 1 516 ? 77.864 73.452 -14.461 1.00 12.35 ? 516 SER A CB 1 ATOM 4098 O OG . SER A 1 516 ? 78.623 73.950 -13.372 1.00 19.41 ? 516 SER A OG 1 ATOM 4099 N N . PRO A 1 517 ? 75.158 72.069 -12.365 1.00 14.38 ? 517 PRO A N 1 ATOM 4100 C CA . PRO A 1 517 ? 73.927 72.488 -11.698 1.00 14.73 ? 517 PRO A CA 1 ATOM 4101 C C . PRO A 1 517 ? 74.192 73.413 -10.534 1.00 13.67 ? 517 PRO A C 1 ATOM 4102 O O . PRO A 1 517 ? 75.103 73.190 -9.753 1.00 17.74 ? 517 PRO A O 1 ATOM 4103 C CB . PRO A 1 517 ? 73.323 71.175 -11.203 1.00 17.37 ? 517 PRO A CB 1 ATOM 4104 C CG . PRO A 1 517 ? 74.428 70.251 -11.114 1.00 15.61 ? 517 PRO A CG 1 ATOM 4105 C CD . PRO A 1 517 ? 75.373 70.624 -12.222 1.00 13.97 ? 517 PRO A CD 1 ATOM 4106 N N . ASP A 1 518 ? 73.393 74.459 -10.454 1.00 14.73 ? 518 ASP A N 1 ATOM 4107 C CA . ASP A 1 518 ? 73.080 75.128 -9.210 1.00 15.41 ? 518 ASP A CA 1 ATOM 4108 C C . ASP A 1 518 ? 71.663 74.730 -8.827 1.00 12.52 ? 518 ASP A C 1 ATOM 4109 O O . ASP A 1 518 ? 70.720 75.073 -9.512 1.00 13.11 ? 518 ASP A O 1 ATOM 4110 C CB . ASP A 1 518 ? 73.154 76.639 -9.451 1.00 17.93 ? 518 ASP A CB 1 ATOM 4111 C CG . ASP A 1 518 ? 72.755 77.456 -8.248 1.00 23.25 ? 518 ASP A CG 1 ATOM 4112 O OD1 . ASP A 1 518 ? 72.088 76.938 -7.346 1.00 19.06 ? 518 ASP A OD1 1 ATOM 4113 O OD2 . ASP A 1 518 ? 73.099 78.650 -8.227 1.00 27.19 ? 518 ASP A OD2 1 ATOM 4114 N N . PHE A 1 519 ? 71.525 73.984 -7.744 1.00 14.51 ? 519 PHE A N 1 ATOM 4115 C CA . PHE A 1 519 ? 70.226 73.432 -7.385 1.00 13.43 ? 519 PHE A CA 1 ATOM 4116 C C . PHE A 1 519 ? 69.166 74.409 -6.977 1.00 14.61 ? 519 PHE A C 1 ATOM 4117 O O . PHE A 1 519 ? 68.010 74.004 -6.794 1.00 15.82 ? 519 PHE A O 1 ATOM 4118 C CB . PHE A 1 519 ? 70.407 72.333 -6.351 1.00 14.09 ? 519 PHE A CB 1 ATOM 4119 C CG . PHE A 1 519 ? 71.258 71.177 -6.855 1.00 13.22 ? 519 PHE A CG 1 ATOM 4120 C CD1 . PHE A 1 519 ? 70.963 70.499 -8.068 1.00 13.70 ? 519 PHE A CD1 1 ATOM 4121 C CD2 . PHE A 1 519 ? 72.340 70.756 -6.079 1.00 15.75 ? 519 PHE A CD2 1 ATOM 4122 C CE1 . PHE A 1 519 ? 71.734 69.431 -8.491 1.00 14.61 ? 519 PHE A CE1 1 ATOM 4123 C CE2 . PHE A 1 519 ? 73.117 69.690 -6.479 1.00 14.67 ? 519 PHE A CE2 1 ATOM 4124 C CZ . PHE A 1 519 ? 72.829 69.017 -7.689 1.00 15.65 ? 519 PHE A CZ 1 ATOM 4125 N N . SER A 1 520 ? 69.497 75.694 -6.854 1.00 14.39 ? 520 SER A N 1 ATOM 4126 C CA . SER A 1 520 ? 68.471 76.715 -6.513 1.00 16.91 ? 520 SER A CA 1 ATOM 4127 C C . SER A 1 520 ? 68.113 77.538 -7.771 1.00 14.76 ? 520 SER A C 1 ATOM 4128 O O . SER A 1 520 ? 67.201 78.349 -7.718 1.00 16.35 ? 520 SER A O 1 ATOM 4129 C CB . SER A 1 520 ? 69.019 77.732 -5.496 1.00 17.70 ? 520 SER A CB 1 ATOM 4130 O OG . SER A 1 520 ? 70.111 78.437 -6.108 1.00 22.20 ? 520 SER A OG 1 ATOM 4131 N N . PHE A 1 521 ? 68.813 77.283 -8.887 1.00 14.10 ? 521 PHE A N 1 ATOM 4132 C CA . PHE A 1 521 ? 68.626 78.083 -10.104 1.00 14.38 ? 521 PHE A CA 1 ATOM 4133 C C . PHE A 1 521 ? 67.518 77.582 -11.000 1.00 12.47 ? 521 PHE A C 1 ATOM 4134 O O . PHE A 1 521 ? 67.261 76.385 -11.044 1.00 15.39 ? 521 PHE A O 1 ATOM 4135 C CB . PHE A 1 521 ? 69.961 78.086 -10.896 1.00 14.61 ? 521 PHE A CB 1 ATOM 4136 C CG . PHE A 1 521 ? 69.986 79.073 -12.036 1.00 16.23 ? 521 PHE A CG 1 ATOM 4137 C CD1 . PHE A 1 521 ? 70.146 80.449 -11.771 1.00 20.17 ? 521 PHE A CD1 1 ATOM 4138 C CD2 . PHE A 1 521 ? 69.800 78.659 -13.365 1.00 16.63 ? 521 PHE A CD2 1 ATOM 4139 C CE1 . PHE A 1 521 ? 70.105 81.397 -12.812 1.00 25.11 ? 521 PHE A CE1 1 ATOM 4140 C CE2 . PHE A 1 521 ? 69.754 79.580 -14.412 1.00 20.03 ? 521 PHE A CE2 1 ATOM 4141 C CZ . PHE A 1 521 ? 69.904 80.957 -14.146 1.00 25.65 ? 521 PHE A CZ 1 ATOM 4142 N N . SER A 1 522 ? 66.872 78.495 -11.696 1.00 14.60 ? 522 SER A N 1 ATOM 4143 C CA . SER A 1 522 ? 65.817 78.160 -12.655 1.00 14.38 ? 522 SER A CA 1 ATOM 4144 C C . SER A 1 522 ? 66.383 78.113 -14.069 1.00 12.76 ? 522 SER A C 1 ATOM 4145 O O . SER A 1 522 ? 66.512 79.152 -14.747 1.00 16.78 ? 522 SER A O 1 ATOM 4146 C CB . SER A 1 522 ? 64.695 79.205 -12.591 1.00 20.83 ? 522 SER A CB 1 ATOM 4147 O OG . SER A 1 522 ? 63.916 78.977 -11.417 1.00 30.03 ? 522 SER A OG 1 ATOM 4148 N N . TYR A 1 523 ? 66.707 76.911 -14.527 1.00 9.48 ? 523 TYR A N 1 ATOM 4149 C CA . TYR A 1 523 ? 67.161 76.677 -15.898 1.00 8.92 ? 523 TYR A CA 1 ATOM 4150 C C . TYR A 1 523 ? 66.047 76.768 -16.925 1.00 10.25 ? 523 TYR A C 1 ATOM 4151 O O . TYR A 1 523 ? 66.240 77.167 -18.046 1.00 10.26 ? 523 TYR A O 1 ATOM 4152 C CB . TYR A 1 523 ? 67.857 75.305 -16.001 1.00 10.56 ? 523 TYR A CB 1 ATOM 4153 C CG . TYR A 1 523 ? 69.131 75.293 -15.199 1.00 9.67 ? 523 TYR A CG 1 ATOM 4154 C CD1 . TYR A 1 523 ? 70.288 75.871 -15.707 1.00 12.93 ? 523 TYR A CD1 1 ATOM 4155 C CD2 . TYR A 1 523 ? 69.159 74.777 -13.918 1.00 11.15 ? 523 TYR A CD2 1 ATOM 4156 C CE1 . TYR A 1 523 ? 71.446 75.890 -14.976 1.00 13.81 ? 523 TYR A CE1 1 ATOM 4157 C CE2 . TYR A 1 523 ? 70.311 74.791 -13.185 1.00 12.77 ? 523 TYR A CE2 1 ATOM 4158 C CZ . TYR A 1 523 ? 71.448 75.358 -13.715 1.00 16.98 ? 523 TYR A CZ 1 ATOM 4159 O OH . TYR A 1 523 ? 72.582 75.380 -12.938 1.00 16.37 ? 523 TYR A OH 1 ATOM 4160 N N . PHE A 1 524 ? 64.862 76.360 -16.509 1.00 8.78 ? 524 PHE A N 1 ATOM 4161 C CA . PHE A 1 524 ? 63.681 76.424 -17.372 1.00 7.95 ? 524 PHE A CA 1 ATOM 4162 C C . PHE A 1 524 ? 62.487 76.877 -16.540 1.00 10.96 ? 524 PHE A C 1 ATOM 4163 O O . PHE A 1 524 ? 62.415 76.632 -15.321 1.00 11.72 ? 524 PHE A O 1 ATOM 4164 C CB . PHE A 1 524 ? 63.250 75.032 -17.942 1.00 8.86 ? 524 PHE A CB 1 ATOM 4165 C CG . PHE A 1 524 ? 64.292 74.375 -18.802 1.00 8.33 ? 524 PHE A CG 1 ATOM 4166 C CD1 . PHE A 1 524 ? 65.310 73.614 -18.218 1.00 9.70 ? 524 PHE A CD1 1 ATOM 4167 C CD2 . PHE A 1 524 ? 64.253 74.535 -20.197 1.00 9.10 ? 524 PHE A CD2 1 ATOM 4168 C CE1 . PHE A 1 524 ? 66.283 73.024 -19.035 1.00 10.56 ? 524 PHE A CE1 1 ATOM 4169 C CE2 . PHE A 1 524 ? 65.238 73.926 -21.019 1.00 9.21 ? 524 PHE A CE2 1 ATOM 4170 C CZ . PHE A 1 524 ? 66.235 73.190 -20.438 1.00 9.36 ? 524 PHE A CZ 1 ATOM 4171 N N . THR A 1 525 ? 61.546 77.500 -17.234 1.00 10.54 ? 525 THR A N 1 ATOM 4172 C CA . THR A 1 525 ? 60.266 77.779 -16.599 1.00 14.84 ? 525 THR A CA 1 ATOM 4173 C C . THR A 1 525 ? 59.204 76.992 -17.356 1.00 10.83 ? 525 THR A C 1 ATOM 4174 O O . THR A 1 525 ? 59.273 76.828 -18.609 1.00 12.56 ? 525 THR A O 1 ATOM 4175 C CB . THR A 1 525 ? 59.894 79.229 -16.583 1.00 17.19 ? 525 THR A CB 1 ATOM 4176 O OG1 . THR A 1 525 ? 59.831 79.683 -17.897 1.00 20.35 ? 525 THR A OG1 1 ATOM 4177 C CG2 . THR A 1 525 ? 60.976 80.066 -15.861 1.00 20.59 ? 525 THR A CG2 1 ATOM 4178 N N . LEU A 1 526 ? 58.212 76.509 -16.627 1.00 10.59 ? 526 LEU A N 1 ATOM 4179 C CA . LEU A 1 526 ? 57.144 75.787 -17.230 1.00 11.59 ? 526 LEU A CA 1 ATOM 4180 C C . LEU A 1 526 ? 56.198 76.762 -17.904 1.00 11.77 ? 526 LEU A C 1 ATOM 4181 O O . LEU A 1 526 ? 55.977 77.892 -17.419 1.00 14.95 ? 526 LEU A O 1 ATOM 4182 C CB . LEU A 1 526 ? 56.341 75.002 -16.159 1.00 14.56 ? 526 LEU A CB 1 ATOM 4183 C CG . LEU A 1 526 ? 56.822 73.609 -15.773 1.00 15.80 ? 526 LEU A CG 1 ATOM 4184 C CD1 . LEU A 1 526 ? 55.988 73.102 -14.555 1.00 20.64 ? 526 LEU A CD1 1 ATOM 4185 C CD2 . LEU A 1 526 ? 56.653 72.674 -16.963 1.00 16.44 ? 526 LEU A CD2 1 ATOM 4186 N N . ASP A 1 527 ? 55.614 76.338 -18.999 1.00 8.62 ? 527 ASP A N 1 ATOM 4187 C CA . ASP A 1 527 ? 54.633 77.132 -19.671 1.00 10.19 ? 527 ASP A CA 1 ATOM 4188 C C . ASP A 1 527 ? 53.382 76.257 -19.717 1.00 9.54 ? 527 ASP A C 1 ATOM 4189 O O . ASP A 1 527 ? 53.424 75.155 -20.245 1.00 15.32 ? 527 ASP A O 1 ATOM 4190 C CB . ASP A 1 527 ? 55.102 77.521 -21.095 1.00 10.77 ? 527 ASP A CB 1 ATOM 4191 C CG . ASP A 1 527 ? 54.086 78.388 -21.817 1.00 15.66 ? 527 ASP A CG 1 ATOM 4192 O OD1 . ASP A 1 527 ? 53.771 79.490 -21.322 1.00 16.21 ? 527 ASP A OD1 1 ATOM 4193 O OD2 . ASP A 1 527 ? 53.582 77.973 -22.885 1.00 17.92 ? 527 ASP A OD2 1 ATOM 4194 N N . ASP A 1 528 ? 52.281 76.690 -19.157 1.00 9.98 ? 528 ASP A N 1 ATOM 4195 C CA . ASP A 1 528 ? 51.067 75.875 -19.151 1.00 9.44 ? 528 ASP A CA 1 ATOM 4196 C C . ASP A 1 528 ? 49.973 76.717 -19.760 1.00 10.13 ? 528 ASP A C 1 ATOM 4197 O O . ASP A 1 528 ? 49.624 77.763 -19.241 1.00 11.39 ? 528 ASP A O 1 ATOM 4198 C CB . ASP A 1 528 ? 50.736 75.465 -17.711 1.00 10.07 ? 528 ASP A CB 1 ATOM 4199 C CG . ASP A 1 528 ? 49.657 74.417 -17.635 1.00 10.38 ? 528 ASP A CG 1 ATOM 4200 O OD1 . ASP A 1 528 ? 48.656 74.487 -18.354 1.00 11.71 ? 528 ASP A OD1 1 ATOM 4201 O OD2 . ASP A 1 528 ? 49.853 73.469 -16.815 1.00 13.22 ? 528 ASP A OD2 1 ATOM 4202 N N . SER A 1 529 ? 49.435 76.267 -20.892 1.00 10.36 ? 529 SER A N 1 ATOM 4203 C CA . SER A 1 529 ? 48.408 77.045 -21.589 1.00 11.00 ? 529 SER A CA 1 ATOM 4204 C C . SER A 1 529 ? 47.032 76.922 -20.996 1.00 10.44 ? 529 SER A C 1 ATOM 4205 O O . SER A 1 529 ? 46.159 77.685 -21.334 1.00 14.15 ? 529 SER A O 1 ATOM 4206 C CB . SER A 1 529 ? 48.227 76.599 -23.049 1.00 13.42 ? 529 SER A CB 1 ATOM 4207 O OG . SER A 1 529 ? 49.469 76.567 -23.702 1.00 17.80 ? 529 SER A OG 1 ATOM 4208 N N . ARG A 1 530 ? 46.790 75.956 -20.084 1.00 8.44 ? 530 ARG A N 1 ATOM 4209 C CA . ARG A 1 530 ? 45.446 75.769 -19.576 1.00 9.51 ? 530 ARG A CA 1 ATOM 4210 C C . ARG A 1 530 ? 45.328 75.876 -18.083 1.00 10.66 ? 530 ARG A C 1 ATOM 4211 O O . ARG A 1 530 ? 44.261 75.532 -17.553 1.00 15.49 ? 530 ARG A O 1 ATOM 4212 C CB . ARG A 1 530 ? 44.899 74.409 -20.091 1.00 8.65 ? 530 ARG A CB 1 ATOM 4213 C CG . ARG A 1 530 ? 44.946 74.349 -21.642 1.00 10.11 ? 530 ARG A CG 1 ATOM 4214 C CD . ARG A 1 530 ? 44.258 73.103 -22.259 1.00 9.88 ? 530 ARG A CD 1 ATOM 4215 N NE . ARG A 1 530 ? 44.933 71.907 -21.810 1.00 10.30 ? 530 ARG A NE 1 ATOM 4216 C CZ . ARG A 1 530 ? 44.722 70.689 -22.327 1.00 10.83 ? 530 ARG A CZ 1 ATOM 4217 N NH1 . ARG A 1 530 ? 43.872 70.535 -23.314 1.00 12.60 ? 530 ARG A NH1 1 ATOM 4218 N NH2 . ARG A 1 530 ? 45.365 69.645 -21.826 1.00 13.87 ? 530 ARG A NH2 1 ATOM 4219 N N . TRP A 1 531 ? 46.372 76.265 -17.379 1.00 8.68 ? 531 TRP A N 1 ATOM 4220 C CA . TRP A 1 531 ? 46.224 76.520 -15.947 1.00 9.27 ? 531 TRP A CA 1 ATOM 4221 C C . TRP A 1 531 ? 47.147 77.621 -15.521 1.00 9.01 ? 531 TRP A C 1 ATOM 4222 O O . TRP A 1 531 ? 48.308 77.545 -15.812 1.00 10.88 ? 531 TRP A O 1 ATOM 4223 C CB . TRP A 1 531 ? 46.557 75.296 -15.105 1.00 10.42 ? 531 TRP A CB 1 ATOM 4224 C CG . TRP A 1 531 ? 46.459 75.651 -13.671 1.00 11.18 ? 531 TRP A CG 1 ATOM 4225 C CD1 . TRP A 1 531 ? 47.472 76.042 -12.841 1.00 15.36 ? 531 TRP A CD1 1 ATOM 4226 C CD2 . TRP A 1 531 ? 45.266 75.719 -12.909 1.00 13.49 ? 531 TRP A CD2 1 ATOM 4227 N NE1 . TRP A 1 531 ? 46.974 76.313 -11.599 1.00 19.29 ? 531 TRP A NE1 1 ATOM 4228 C CE2 . TRP A 1 531 ? 45.620 76.135 -11.614 1.00 11.62 ? 531 TRP A CE2 1 ATOM 4229 C CE3 . TRP A 1 531 ? 43.941 75.440 -13.185 1.00 11.63 ? 531 TRP A CE3 1 ATOM 4230 C CZ2 . TRP A 1 531 ? 44.685 76.291 -10.602 1.00 17.51 ? 531 TRP A CZ2 1 ATOM 4231 C CZ3 . TRP A 1 531 ? 43.011 75.604 -12.186 1.00 14.69 ? 531 TRP A CZ3 1 ATOM 4232 C CH2 . TRP A 1 531 ? 43.388 76.017 -10.910 1.00 16.45 ? 531 TRP A CH2 1 ATOM 4233 N N . PRO A 1 532 ? 46.633 78.633 -14.831 1.00 9.85 ? 532 PRO A N 1 ATOM 4234 C CA . PRO A 1 532 ? 45.233 78.827 -14.437 1.00 10.18 ? 532 PRO A CA 1 ATOM 4235 C C . PRO A 1 532 ? 44.356 79.095 -15.656 1.00 11.95 ? 532 PRO A C 1 ATOM 4236 O O . PRO A 1 532 ? 43.132 78.952 -15.607 1.00 13.17 ? 532 PRO A O 1 ATOM 4237 C CB . PRO A 1 532 ? 45.280 80.061 -13.471 1.00 12.58 ? 532 PRO A CB 1 ATOM 4238 C CG . PRO A 1 532 ? 46.678 79.932 -12.851 1.00 14.18 ? 532 PRO A CG 1 ATOM 4239 C CD . PRO A 1 532 ? 47.544 79.547 -14.076 1.00 11.61 ? 532 PRO A CD 1 ATOM 4240 N N . GLY A 1 533 ? 44.990 79.470 -16.767 1.00 11.21 ? 533 GLY A N 1 ATOM 4241 C CA . GLY A 1 533 ? 44.247 79.671 -18.001 1.00 13.54 ? 533 GLY A CA 1 ATOM 4242 C C . GLY A 1 533 ? 44.045 81.129 -18.376 1.00 18.37 ? 533 GLY A C 1 ATOM 4243 O O . GLY A 1 533 ? 44.050 82.047 -17.535 1.00 18.08 ? 533 GLY A O 1 ATOM 4244 N N . SER A 1 534 ? 43.936 81.315 -19.694 1.00 20.99 ? 534 SER A N 1 ATOM 4245 C CA . SER A 1 534 ? 43.741 82.632 -20.290 1.00 21.31 ? 534 SER A CA 1 ATOM 4246 C C . SER A 1 534 ? 42.472 83.181 -19.670 1.00 21.40 ? 534 SER A C 1 ATOM 4247 O O . SER A 1 534 ? 41.420 82.507 -19.661 1.00 24.57 ? 534 SER A O 1 ATOM 4248 C CB . SER A 1 534 ? 43.602 82.476 -21.802 1.00 28.92 ? 534 SER A CB 1 ATOM 4249 O OG . SER A 1 534 ? 43.632 83.736 -22.450 1.00 34.63 ? 534 SER A OG 1 ATOM 4250 N N . GLY A 1 535 ? 42.543 84.402 -19.141 1.00 23.98 ? 535 GLY A N 1 ATOM 4251 C CA . GLY A 1 535 ? 41.370 84.977 -18.514 1.00 24.06 ? 535 GLY A CA 1 ATOM 4252 C C . GLY A 1 535 ? 41.239 84.694 -17.032 1.00 24.86 ? 535 GLY A C 1 ATOM 4253 O O . GLY A 1 535 ? 40.347 85.249 -16.323 1.00 27.27 ? 535 GLY A O 1 ATOM 4254 N N . VAL A 1 536 ? 42.112 83.823 -16.520 1.00 23.08 ? 536 VAL A N 1 ATOM 4255 C CA . VAL A 1 536 ? 42.060 83.478 -15.096 1.00 21.62 ? 536 VAL A CA 1 ATOM 4256 C C . VAL A 1 536 ? 43.247 84.167 -14.407 1.00 21.79 ? 536 VAL A C 1 ATOM 4257 O O . VAL A 1 536 ? 43.058 84.865 -13.404 1.00 21.03 ? 536 VAL A O 1 ATOM 4258 C CB . VAL A 1 536 ? 42.064 81.912 -14.937 1.00 20.97 ? 536 VAL A CB 1 ATOM 4259 C CG1 . VAL A 1 536 ? 41.898 81.482 -13.473 1.00 21.13 ? 536 VAL A CG1 1 ATOM 4260 C CG2 . VAL A 1 536 ? 40.865 81.343 -15.706 1.00 20.32 ? 536 VAL A CG2 1 ATOM 4261 N N . GLU A 1 537 ? 44.449 83.954 -14.924 1.00 20.50 ? 537 GLU A N 1 ATOM 4262 C CA . GLU A 1 537 ? 45.622 84.686 -14.454 1.00 21.21 ? 537 GLU A CA 1 ATOM 4263 C C . GLU A 1 537 ? 46.528 84.979 -15.645 1.00 21.23 ? 537 GLU A C 1 ATOM 4264 O O . GLU A 1 537 ? 46.616 84.182 -16.574 1.00 24.00 ? 537 GLU A O 1 ATOM 4265 C CB . GLU A 1 537 ? 46.372 83.871 -13.391 1.00 23.09 ? 537 GLU A CB 1 ATOM 4266 C CG . GLU A 1 537 ? 45.511 83.436 -12.204 1.00 26.84 ? 537 GLU A CG 1 ATOM 4267 C CD . GLU A 1 537 ? 45.220 84.556 -11.225 1.00 36.64 ? 537 GLU A CD 1 ATOM 4268 O OE1 . GLU A 1 537 ? 45.570 85.715 -11.508 1.00 38.91 ? 537 GLU A OE1 1 ATOM 4269 O OE2 . GLU A 1 537 ? 44.635 84.277 -10.165 1.00 34.25 ? 537 GLU A OE2 1 ATOM 4270 N N . ASP A 1 538 ? 47.202 86.123 -15.625 1.00 24.65 ? 538 ASP A N 1 ATOM 4271 C CA . ASP A 1 538 ? 48.314 86.309 -16.549 1.00 30.94 ? 538 ASP A CA 1 ATOM 4272 C C . ASP A 1 538 ? 49.595 85.778 -15.951 1.00 30.37 ? 538 ASP A C 1 ATOM 4273 O O . ASP A 1 538 ? 50.292 86.468 -15.225 1.00 31.57 ? 538 ASP A O 1 ATOM 4274 C CB . ASP A 1 538 ? 48.487 87.760 -17.003 1.00 35.50 ? 538 ASP A CB 1 ATOM 4275 C CG . ASP A 1 538 ? 49.612 87.915 -18.027 1.00 42.84 ? 538 ASP A CG 1 ATOM 4276 O OD1 . ASP A 1 538 ? 50.773 87.643 -17.675 1.00 41.45 ? 538 ASP A OD1 1 ATOM 4277 O OD2 . ASP A 1 538 ? 49.342 88.304 -19.182 1.00 43.19 ? 538 ASP A OD2 1 ATOM 4278 N N . SER A 1 539 ? 49.881 84.522 -16.251 1.00 26.81 ? 539 SER A N 1 ATOM 4279 C CA . SER A 1 539 ? 50.991 83.817 -15.587 1.00 24.70 ? 539 SER A CA 1 ATOM 4280 C C . SER A 1 539 ? 52.099 83.365 -16.527 1.00 24.22 ? 539 SER A C 1 ATOM 4281 O O . SER A 1 539 ? 53.227 83.090 -16.083 1.00 26.16 ? 539 SER A O 1 ATOM 4282 C CB . SER A 1 539 ? 50.432 82.563 -14.874 1.00 25.73 ? 539 SER A CB 1 ATOM 4283 O OG . SER A 1 539 ? 49.824 81.679 -15.825 1.00 30.70 ? 539 SER A OG 1 ATOM 4284 N N . ARG A 1 540 ? 51.755 83.283 -17.807 1.00 22.49 ? 540 ARG A N 1 ATOM 4285 C CA . ARG A 1 540 ? 52.632 82.801 -18.862 1.00 24.05 ? 540 ARG A CA 1 ATOM 4286 C C . ARG A 1 540 ? 53.644 83.805 -19.309 1.00 20.19 ? 540 ARG A C 1 ATOM 4287 O O . ARG A 1 540 ? 53.322 84.974 -19.512 1.00 24.47 ? 540 ARG A O 1 ATOM 4288 C CB . ARG A 1 540 ? 51.811 82.405 -20.066 1.00 23.54 ? 540 ARG A CB 1 ATOM 4289 C CG . ARG A 1 540 ? 51.012 81.101 -19.837 1.00 19.49 ? 540 ARG A CG 1 ATOM 4290 C CD . ARG A 1 540 ? 50.194 80.792 -21.076 1.00 16.84 ? 540 ARG A CD 1 ATOM 4291 N NE . ARG A 1 540 ? 51.010 80.136 -22.116 1.00 14.70 ? 540 ARG A NE 1 ATOM 4292 C CZ . ARG A 1 540 ? 50.566 79.776 -23.318 1.00 14.74 ? 540 ARG A CZ 1 ATOM 4293 N NH1 . ARG A 1 540 ? 49.319 79.970 -23.716 1.00 15.74 ? 540 ARG A NH1 1 ATOM 4294 N NH2 . ARG A 1 540 ? 51.407 79.209 -24.156 1.00 13.30 ? 540 ARG A NH2 1 ATOM 4295 N N . THR A 1 541 ? 54.842 83.318 -19.502 1.00 20.08 ? 541 THR A N 1 ATOM 4296 C CA . THR A 1 541 ? 55.890 84.207 -19.925 1.00 20.48 ? 541 THR A CA 1 ATOM 4297 C C . THR A 1 541 ? 55.920 84.250 -21.447 1.00 18.62 ? 541 THR A C 1 ATOM 4298 O O . THR A 1 541 ? 55.617 83.297 -22.159 1.00 22.46 ? 541 THR A O 1 ATOM 4299 C CB . THR A 1 541 ? 57.238 83.763 -19.398 1.00 28.05 ? 541 THR A CB 1 ATOM 4300 O OG1 . THR A 1 541 ? 57.667 82.674 -20.175 1.00 31.20 ? 541 THR A OG1 1 ATOM 4301 C CG2 . THR A 1 541 ? 57.168 83.316 -17.916 1.00 22.93 ? 541 THR A CG2 1 ATOM 4302 N N . THR A 1 542 ? 56.229 85.432 -21.935 1.00 15.67 ? 542 THR A N 1 ATOM 4303 C CA . THR A 1 542 ? 56.371 85.627 -23.354 1.00 12.84 ? 542 THR A CA 1 ATOM 4304 C C . THR A 1 542 ? 57.849 85.416 -23.653 1.00 10.54 ? 542 THR A C 1 ATOM 4305 O O . THR A 1 542 ? 58.740 85.879 -22.901 1.00 14.04 ? 542 THR A O 1 ATOM 4306 C CB . THR A 1 542 ? 56.050 87.072 -23.717 1.00 13.68 ? 542 THR A CB 1 ATOM 4307 O OG1 . THR A 1 542 ? 54.681 87.308 -23.414 1.00 19.29 ? 542 THR A OG1 1 ATOM 4308 C CG2 . THR A 1 542 ? 56.318 87.374 -25.172 1.00 13.91 ? 542 THR A CG2 1 ATOM 4309 N N . ILE A 1 543 ? 58.111 84.640 -24.702 1.00 9.95 ? 543 ILE A N 1 ATOM 4310 C CA . ILE A 1 543 ? 59.495 84.440 -25.147 1.00 9.77 ? 543 ILE A CA 1 ATOM 4311 C C . ILE A 1 543 ? 59.867 85.742 -25.914 1.00 10.16 ? 543 ILE A C 1 ATOM 4312 O O . ILE A 1 543 ? 59.224 86.052 -26.927 1.00 11.44 ? 543 ILE A O 1 ATOM 4313 C CB . ILE A 1 543 ? 59.565 83.217 -26.044 1.00 10.28 ? 543 ILE A CB 1 ATOM 4314 C CG1 . ILE A 1 543 ? 59.266 81.939 -25.178 1.00 9.73 ? 543 ILE A CG1 1 ATOM 4315 C CG2 . ILE A 1 543 ? 60.936 83.142 -26.756 1.00 10.72 ? 543 ILE A CG2 1 ATOM 4316 C CD1 . ILE A 1 543 ? 59.134 80.691 -26.035 1.00 9.57 ? 543 ILE A CD1 1 ATOM 4317 N N . ILE A 1 544 ? 60.853 86.447 -25.381 1.00 10.63 ? 544 ILE A N 1 ATOM 4318 C CA . ILE A 1 544 ? 61.270 87.743 -25.964 1.00 10.45 ? 544 ILE A CA 1 ATOM 4319 C C . ILE A 1 544 ? 62.452 87.555 -26.898 1.00 11.96 ? 544 ILE A C 1 ATOM 4320 O O . ILE A 1 544 ? 63.584 87.176 -26.473 1.00 12.77 ? 544 ILE A O 1 ATOM 4321 C CB . ILE A 1 544 ? 61.605 88.696 -24.819 1.00 13.00 ? 544 ILE A CB 1 ATOM 4322 C CG1 . ILE A 1 544 ? 60.335 88.871 -23.991 1.00 16.68 ? 544 ILE A CG1 1 ATOM 4323 C CG2 . ILE A 1 544 ? 62.110 90.033 -25.362 1.00 16.76 ? 544 ILE A CG2 1 ATOM 4324 C CD1 . ILE A 1 544 ? 60.412 89.904 -22.876 1.00 25.38 ? 544 ILE A CD1 1 ATOM 4325 N N . LEU A 1 545 ? 62.173 87.783 -28.172 1.00 10.79 ? 545 LEU A N 1 ATOM 4326 C CA . LEU A 1 545 ? 63.170 87.642 -29.222 1.00 10.52 ? 545 LEU A CA 1 ATOM 4327 C C . LEU A 1 545 ? 63.283 89.003 -29.910 1.00 12.90 ? 545 LEU A C 1 ATOM 4328 O O . LEU A 1 545 ? 62.328 89.781 -29.941 1.00 14.41 ? 545 LEU A O 1 ATOM 4329 C CB . LEU A 1 545 ? 62.745 86.582 -30.239 1.00 9.92 ? 545 LEU A CB 1 ATOM 4330 C CG . LEU A 1 545 ? 62.558 85.162 -29.662 1.00 9.87 ? 545 LEU A CG 1 ATOM 4331 C CD1 . LEU A 1 545 ? 62.080 84.227 -30.794 1.00 14.66 ? 545 LEU A CD1 1 ATOM 4332 C CD2 . LEU A 1 545 ? 63.819 84.674 -29.021 1.00 11.76 ? 545 LEU A CD2 1 ATOM 4333 N N . GLY A 1 546 ? 64.434 89.276 -30.493 1.00 11.47 ? 546 GLY A N 1 ATOM 4334 C CA . GLY A 1 546 ? 64.598 90.548 -31.203 1.00 11.61 ? 546 GLY A CA 1 ATOM 4335 C C . GLY A 1 546 ? 65.989 90.564 -31.761 1.00 11.34 ? 546 GLY A C 1 ATOM 4336 O O . GLY A 1 546 ? 66.932 90.052 -31.144 1.00 11.21 ? 546 GLY A O 1 ATOM 4337 N N . GLU A 1 547 ? 66.134 91.260 -32.891 1.00 13.67 ? 547 GLU A N 1 ATOM 4338 C CA . GLU A 1 547 ? 67.450 91.348 -33.546 1.00 17.73 ? 547 GLU A CA 1 ATOM 4339 C C . GLU A 1 547 ? 68.502 92.021 -32.665 1.00 18.27 ? 547 GLU A C 1 ATOM 4340 O O . GLU A 1 547 ? 69.701 91.692 -32.751 1.00 20.78 ? 547 GLU A O 1 ATOM 4341 C CB . GLU A 1 547 ? 67.273 92.120 -34.854 1.00 23.06 ? 547 GLU A CB 1 ATOM 4342 C CG . GLU A 1 547 ? 68.527 92.359 -35.699 1.00 36.38 ? 547 GLU A CG 1 ATOM 4343 C CD . GLU A 1 547 ? 68.190 93.173 -36.967 1.00 39.82 ? 547 GLU A CD 1 ATOM 4344 O OE1 . GLU A 1 547 ? 67.208 92.803 -37.668 1.00 43.82 ? 547 GLU A OE1 1 ATOM 4345 O OE2 . GLU A 1 547 ? 68.900 94.173 -37.272 1.00 43.10 ? 547 GLU A OE2 1 ATOM 4346 N N . ASP A 1 548 ? 68.043 92.909 -31.783 1.00 14.49 ? 548 ASP A N 1 ATOM 4347 C CA . ASP A 1 548 ? 68.959 93.609 -30.894 1.00 14.52 ? 548 ASP A CA 1 ATOM 4348 C C . ASP A 1 548 ? 68.933 93.054 -29.481 1.00 16.99 ? 548 ASP A C 1 ATOM 4349 O O . ASP A 1 548 ? 69.347 93.744 -28.537 1.00 21.15 ? 548 ASP A O 1 ATOM 4350 C CB . ASP A 1 548 ? 68.604 95.113 -30.870 1.00 17.26 ? 548 ASP A CB 1 ATOM 4351 C CG . ASP A 1 548 ? 68.758 95.759 -32.224 1.00 20.06 ? 548 ASP A CG 1 ATOM 4352 O OD1 . ASP A 1 548 ? 69.899 95.780 -32.727 1.00 25.52 ? 548 ASP A OD1 1 ATOM 4353 O OD2 . ASP A 1 548 ? 67.763 96.235 -32.819 1.00 22.18 ? 548 ASP A OD2 1 ATOM 4354 N N . ILE A 1 549 ? 68.433 91.832 -29.288 1.00 14.36 ? 549 ILE A N 1 ATOM 4355 C CA . ILE A 1 549 ? 68.387 91.247 -27.945 1.00 13.82 ? 549 ILE A CA 1 ATOM 4356 C C . ILE A 1 549 ? 68.689 89.743 -27.869 1.00 14.61 ? 549 ILE A C 1 ATOM 4357 O O . ILE A 1 549 ? 69.504 89.333 -27.064 1.00 15.07 ? 549 ILE A O 1 ATOM 4358 C CB . ILE A 1 549 ? 67.090 91.627 -27.150 1.00 14.93 ? 549 ILE A CB 1 ATOM 4359 C CG1 . ILE A 1 549 ? 67.115 91.051 -25.733 1.00 17.93 ? 549 ILE A CG1 1 ATOM 4360 C CG2 . ILE A 1 549 ? 65.825 91.193 -27.865 1.00 13.72 ? 549 ILE A CG2 1 ATOM 4361 C CD1 . ILE A 1 549 ? 67.673 91.952 -24.705 1.00 29.22 ? 549 ILE A CD1 1 ATOM 4362 N N . LEU A 1 550 ? 68.015 88.952 -28.701 1.00 12.92 ? 550 LEU A N 1 ATOM 4363 C CA . LEU A 1 550 ? 68.152 87.484 -28.610 1.00 11.67 ? 550 LEU A CA 1 ATOM 4364 C C . LEU A 1 550 ? 67.498 86.930 -29.856 1.00 10.32 ? 550 LEU A C 1 ATOM 4365 O O . LEU A 1 550 ? 66.312 87.118 -30.073 1.00 12.41 ? 550 LEU A O 1 ATOM 4366 C CB . LEU A 1 550 ? 67.391 87.023 -27.350 1.00 13.06 ? 550 LEU A CB 1 ATOM 4367 C CG . LEU A 1 550 ? 67.462 85.505 -27.169 1.00 12.42 ? 550 LEU A CG 1 ATOM 4368 C CD1 . LEU A 1 550 ? 68.897 85.117 -26.969 1.00 14.97 ? 550 LEU A CD1 1 ATOM 4369 C CD2 . LEU A 1 550 ? 66.662 85.118 -25.954 1.00 14.57 ? 550 LEU A CD2 1 ATOM 4370 N N . PRO A 1 551 ? 68.266 86.235 -30.694 1.00 10.56 ? 551 PRO A N 1 ATOM 4371 C CA . PRO A 1 551 ? 67.652 85.723 -31.907 1.00 11.44 ? 551 PRO A CA 1 ATOM 4372 C C . PRO A 1 551 ? 66.826 84.449 -31.794 1.00 10.34 ? 551 PRO A C 1 ATOM 4373 O O . PRO A 1 551 ? 65.955 84.221 -32.633 1.00 12.00 ? 551 PRO A O 1 ATOM 4374 C CB . PRO A 1 551 ? 68.833 85.499 -32.882 1.00 15.26 ? 551 PRO A CB 1 ATOM 4375 C CG . PRO A 1 551 ? 69.982 85.392 -32.102 1.00 19.12 ? 551 PRO A CG 1 ATOM 4376 C CD . PRO A 1 551 ? 69.742 86.167 -30.747 1.00 14.27 ? 551 PRO A CD 1 ATOM 4377 N N . SER A 1 552 ? 67.076 83.646 -30.749 1.00 9.81 ? 552 SER A N 1 ATOM 4378 C CA . SER A 1 552 ? 66.390 82.353 -30.680 1.00 8.45 ? 552 SER A CA 1 ATOM 4379 C C . SER A 1 552 ? 66.263 81.868 -29.250 1.00 8.52 ? 552 SER A C 1 ATOM 4380 O O . SER A 1 552 ? 66.942 82.354 -28.350 1.00 9.58 ? 552 SER A O 1 ATOM 4381 C CB . SER A 1 552 ? 67.112 81.301 -31.529 1.00 9.94 ? 552 SER A CB 1 ATOM 4382 O OG . SER A 1 552 ? 68.339 80.931 -30.970 1.00 12.32 ? 552 SER A OG 1 ATOM 4383 N N . LYS A 1 553 ? 65.413 80.842 -29.096 1.00 8.48 ? 553 LYS A N 1 ATOM 4384 C CA . LYS A 1 553 ? 65.140 80.264 -27.795 1.00 7.82 ? 553 LYS A CA 1 ATOM 4385 C C . LYS A 1 553 ? 64.864 78.750 -27.908 1.00 7.05 ? 553 LYS A C 1 ATOM 4386 O O . LYS A 1 553 ? 64.046 78.334 -28.747 1.00 8.14 ? 553 LYS A O 1 ATOM 4387 C CB . LYS A 1 553 ? 63.850 80.925 -27.227 1.00 8.72 ? 553 LYS A CB 1 ATOM 4388 C CG . LYS A 1 553 ? 63.371 80.342 -25.816 1.00 8.59 ? 553 LYS A CG 1 ATOM 4389 C CD . LYS A 1 553 ? 64.409 80.505 -24.784 1.00 9.07 ? 553 LYS A CD 1 ATOM 4390 C CE . LYS A 1 553 ? 64.614 81.962 -24.391 1.00 10.35 ? 553 LYS A CE 1 ATOM 4391 N NZ . LYS A 1 553 ? 65.800 82.078 -23.460 1.00 12.32 ? 553 LYS A NZ 1 ATOM 4392 N N . HIS A 1 554 ? 65.503 77.984 -27.036 1.00 7.88 ? 554 HIS A N 1 ATOM 4393 C CA . HIS A 1 554 ? 65.235 76.564 -26.907 1.00 7.50 ? 554 HIS A CA 1 ATOM 4394 C C . HIS A 1 554 ? 64.031 76.328 -25.994 1.00 6.48 ? 554 HIS A C 1 ATOM 4395 O O . HIS A 1 554 ? 63.899 76.938 -24.953 1.00 8.98 ? 554 HIS A O 1 ATOM 4396 C CB . HIS A 1 554 ? 66.439 75.857 -26.302 1.00 9.53 ? 554 HIS A CB 1 ATOM 4397 C CG . HIS A 1 554 ? 67.581 75.666 -27.249 1.00 10.90 ? 554 HIS A CG 1 ATOM 4398 N ND1 . HIS A 1 554 ? 68.113 76.683 -28.013 1.00 16.81 ? 554 HIS A ND1 1 ATOM 4399 C CD2 . HIS A 1 554 ? 68.305 74.562 -27.536 1.00 10.60 ? 554 HIS A CD2 1 ATOM 4400 C CE1 . HIS A 1 554 ? 69.117 76.211 -28.729 1.00 10.53 ? 554 HIS A CE1 1 ATOM 4401 N NE2 . HIS A 1 554 ? 69.248 74.925 -28.460 1.00 19.01 ? 554 HIS A NE2 1 ATOM 4402 N N . VAL A 1 555 ? 63.173 75.412 -26.408 1.00 6.65 ? 555 VAL A N 1 ATOM 4403 C CA . VAL A 1 555 ? 62.046 74.952 -25.609 1.00 7.65 ? 555 VAL A CA 1 ATOM 4404 C C . VAL A 1 555 ? 62.114 73.414 -25.606 1.00 8.00 ? 555 VAL A C 1 ATOM 4405 O O . VAL A 1 555 ? 62.644 72.781 -26.541 1.00 7.92 ? 555 VAL A O 1 ATOM 4406 C CB . VAL A 1 555 ? 60.681 75.417 -26.143 1.00 6.50 ? 555 VAL A CB 1 ATOM 4407 C CG1 . VAL A 1 555 ? 60.571 76.940 -26.069 1.00 8.87 ? 555 VAL A CG1 1 ATOM 4408 C CG2 . VAL A 1 555 ? 60.433 74.979 -27.571 1.00 7.70 ? 555 VAL A CG2 1 ATOM 4409 N N . VAL A 1 556 ? 61.558 72.800 -24.547 1.00 6.75 ? 556 VAL A N 1 ATOM 4410 C CA . VAL A 1 556 ? 61.612 71.346 -24.439 1.00 6.33 ? 556 VAL A CA 1 ATOM 4411 C C . VAL A 1 556 ? 60.219 70.840 -24.033 1.00 6.11 ? 556 VAL A C 1 ATOM 4412 O O . VAL A 1 556 ? 59.568 71.427 -23.149 1.00 6.60 ? 556 VAL A O 1 ATOM 4413 C CB . VAL A 1 556 ? 62.604 70.938 -23.308 1.00 6.40 ? 556 VAL A CB 1 ATOM 4414 C CG1 . VAL A 1 556 ? 62.530 69.416 -23.064 1.00 7.46 ? 556 VAL A CG1 1 ATOM 4415 C CG2 . VAL A 1 556 ? 64.050 71.320 -23.648 1.00 8.78 ? 556 VAL A CG2 1 ATOM 4416 N N . MET A 1 557 ? 59.776 69.744 -24.653 1.00 6.18 ? 557 MET A N 1 ATOM 4417 C CA . MET A 1 557 ? 58.528 69.090 -24.257 1.00 6.27 ? 557 MET A CA 1 ATOM 4418 C C . MET A 1 557 ? 58.806 67.746 -23.608 1.00 7.21 ? 557 MET A C 1 ATOM 4419 O O . MET A 1 557 ? 59.701 67.020 -24.027 1.00 7.75 ? 557 MET A O 1 ATOM 4420 C CB . MET A 1 557 ? 57.620 68.809 -25.469 1.00 6.01 ? 557 MET A CB 1 ATOM 4421 C CG . MET A 1 557 ? 56.644 69.974 -25.807 1.00 7.34 ? 557 MET A CG 1 ATOM 4422 S SD . MET A 1 557 ? 57.300 71.616 -25.976 1.00 8.78 ? 557 MET A SD 1 ATOM 4423 C CE . MET A 1 557 ? 58.255 71.629 -27.492 1.00 28.99 ? 557 MET A CE 1 ATOM 4424 N N . HIS A 1 558 ? 58.031 67.458 -22.556 1.00 6.01 ? 558 HIS A N 1 ATOM 4425 C CA . HIS A 1 558 ? 58.077 66.164 -21.888 1.00 5.31 ? 558 HIS A CA 1 ATOM 4426 C C . HIS A 1 558 ? 56.773 65.429 -22.102 1.00 5.76 ? 558 HIS A C 1 ATOM 4427 O O . HIS A 1 558 ? 55.681 66.003 -22.085 1.00 6.71 ? 558 HIS A O 1 ATOM 4428 C CB . HIS A 1 558 ? 58.265 66.355 -20.376 1.00 6.78 ? 558 HIS A CB 1 ATOM 4429 C CG . HIS A 1 558 ? 58.194 65.076 -19.584 1.00 6.02 ? 558 HIS A CG 1 ATOM 4430 N ND1 . HIS A 1 558 ? 57.248 64.909 -18.579 1.00 6.93 ? 558 HIS A ND1 1 ATOM 4431 C CD2 . HIS A 1 558 ? 58.934 63.934 -19.613 1.00 6.74 ? 558 HIS A CD2 1 ATOM 4432 C CE1 . HIS A 1 558 ? 57.442 63.719 -18.011 1.00 6.30 ? 558 HIS A CE1 1 ATOM 4433 N NE2 . HIS A 1 558 ? 58.449 63.096 -18.620 1.00 7.36 ? 558 HIS A NE2 1 ATOM 4434 N N . ASN A 1 559 ? 56.915 64.102 -22.350 1.00 5.26 ? 559 ASN A N 1 ATOM 4435 C CA . ASN A 1 559 ? 55.756 63.215 -22.525 1.00 5.69 ? 559 ASN A CA 1 ATOM 4436 C C . ASN A 1 559 ? 55.778 62.129 -21.438 1.00 5.46 ? 559 ASN A C 1 ATOM 4437 O O . ASN A 1 559 ? 56.540 61.176 -21.562 1.00 6.90 ? 559 ASN A O 1 ATOM 4438 C CB . ASN A 1 559 ? 55.838 62.577 -23.914 1.00 6.07 ? 559 ASN A CB 1 ATOM 4439 C CG . ASN A 1 559 ? 54.842 61.484 -24.117 1.00 6.07 ? 559 ASN A CG 1 ATOM 4440 O OD1 . ASN A 1 559 ? 53.750 61.488 -23.549 1.00 7.47 ? 559 ASN A OD1 1 ATOM 4441 N ND2 . ASN A 1 559 ? 55.213 60.507 -24.984 1.00 7.38 ? 559 ASN A ND2 1 ATOM 4442 N N . THR A 1 560 ? 54.907 62.246 -20.437 1.00 5.51 ? 560 THR A N 1 ATOM 4443 C CA . THR A 1 560 ? 54.924 61.252 -19.353 1.00 5.87 ? 560 THR A CA 1 ATOM 4444 C C . THR A 1 560 ? 54.345 59.886 -19.749 1.00 7.00 ? 560 THR A C 1 ATOM 4445 O O . THR A 1 560 ? 54.527 58.908 -19.018 1.00 7.33 ? 560 THR A O 1 ATOM 4446 C CB . THR A 1 560 ? 54.181 61.864 -18.168 1.00 5.44 ? 560 THR A CB 1 ATOM 4447 O OG1 . THR A 1 560 ? 54.467 61.128 -16.935 1.00 6.62 ? 560 THR A OG1 1 ATOM 4448 C CG2 . THR A 1 560 ? 52.676 61.916 -18.362 1.00 6.83 ? 560 THR A CG2 1 ATOM 4449 N N . LEU A 1 561 ? 53.606 59.826 -20.843 1.00 6.49 ? 561 LEU A N 1 ATOM 4450 C CA . LEU A 1 561 ? 52.992 58.545 -21.270 1.00 6.69 ? 561 LEU A CA 1 ATOM 4451 C C . LEU A 1 561 ? 53.996 57.638 -21.953 1.00 5.90 ? 561 LEU A C 1 ATOM 4452 O O . LEU A 1 561 ? 54.889 58.090 -22.670 1.00 6.90 ? 561 LEU A O 1 ATOM 4453 C CB . LEU A 1 561 ? 51.885 58.853 -22.265 1.00 6.53 ? 561 LEU A CB 1 ATOM 4454 C CG . LEU A 1 561 ? 50.761 59.756 -21.697 1.00 7.31 ? 561 LEU A CG 1 ATOM 4455 C CD1 . LEU A 1 561 ? 49.712 59.935 -22.822 1.00 9.41 ? 561 LEU A CD1 1 ATOM 4456 C CD2 . LEU A 1 561 ? 50.075 59.161 -20.437 1.00 8.58 ? 561 LEU A CD2 1 ATOM 4457 N N . PRO A 1 562 ? 53.855 56.329 -21.791 1.00 6.45 ? 562 PRO A N 1 ATOM 4458 C CA . PRO A 1 562 ? 54.805 55.369 -22.376 1.00 6.58 ? 562 PRO A CA 1 ATOM 4459 C C . PRO A 1 562 ? 54.633 54.990 -23.834 1.00 6.70 ? 562 PRO A C 1 ATOM 4460 O O . PRO A 1 562 ? 54.782 53.818 -24.182 1.00 8.10 ? 562 PRO A O 1 ATOM 4461 C CB . PRO A 1 562 ? 54.696 54.168 -21.396 1.00 7.59 ? 562 PRO A CB 1 ATOM 4462 C CG . PRO A 1 562 ? 53.173 54.173 -21.150 1.00 7.14 ? 562 PRO A CG 1 ATOM 4463 C CD . PRO A 1 562 ? 52.882 55.654 -20.886 1.00 6.39 ? 562 PRO A CD 1 ATOM 4464 N N . HIS A 1 563 ? 54.280 55.963 -24.672 1.00 7.35 ? 563 HIS A N 1 ATOM 4465 C CA . HIS A 1 563 ? 54.225 55.713 -26.107 1.00 7.26 ? 563 HIS A CA 1 ATOM 4466 C C . HIS A 1 563 ? 54.616 56.999 -26.784 1.00 7.79 ? 563 HIS A C 1 ATOM 4467 O O . HIS A 1 563 ? 54.468 58.092 -26.204 1.00 8.08 ? 563 HIS A O 1 ATOM 4468 C CB . HIS A 1 563 ? 52.813 55.249 -26.578 1.00 8.44 ? 563 HIS A CB 1 ATOM 4469 C CG . HIS A 1 563 ? 51.682 56.120 -26.130 1.00 8.41 ? 563 HIS A CG 1 ATOM 4470 N ND1 . HIS A 1 563 ? 50.874 55.788 -25.061 1.00 8.34 ? 563 HIS A ND1 1 ATOM 4471 C CD2 . HIS A 1 563 ? 51.176 57.282 -26.628 1.00 9.29 ? 563 HIS A CD2 1 ATOM 4472 C CE1 . HIS A 1 563 ? 49.923 56.693 -24.917 1.00 9.20 ? 563 HIS A CE1 1 ATOM 4473 N NE2 . HIS A 1 563 ? 50.090 57.624 -25.846 1.00 9.81 ? 563 HIS A NE2 1 ATOM 4474 N N . TRP A 1 564 ? 55.131 56.904 -27.997 1.00 8.27 ? 564 TRP A N 1 ATOM 4475 C CA . TRP A 1 564 ? 55.463 58.106 -28.776 1.00 6.67 ? 564 TRP A CA 1 ATOM 4476 C C . TRP A 1 564 ? 54.190 58.927 -28.908 1.00 8.85 ? 564 TRP A C 1 ATOM 4477 O O . TRP A 1 564 ? 53.062 58.413 -29.095 1.00 8.72 ? 564 TRP A O 1 ATOM 4478 C CB . TRP A 1 564 ? 55.927 57.701 -30.195 1.00 9.24 ? 564 TRP A CB 1 ATOM 4479 C CG . TRP A 1 564 ? 57.356 57.304 -30.271 1.00 8.64 ? 564 TRP A CG 1 ATOM 4480 C CD1 . TRP A 1 564 ? 57.869 56.023 -30.122 1.00 10.47 ? 564 TRP A CD1 1 ATOM 4481 C CD2 . TRP A 1 564 ? 58.481 58.174 -30.439 1.00 10.11 ? 564 TRP A CD2 1 ATOM 4482 N NE1 . TRP A 1 564 ? 59.228 56.080 -30.187 1.00 11.99 ? 564 TRP A NE1 1 ATOM 4483 C CE2 . TRP A 1 564 ? 59.643 57.377 -30.376 1.00 10.42 ? 564 TRP A CE2 1 ATOM 4484 C CE3 . TRP A 1 564 ? 58.617 59.566 -30.631 1.00 11.75 ? 564 TRP A CE3 1 ATOM 4485 C CZ2 . TRP A 1 564 ? 60.953 57.921 -30.503 1.00 12.44 ? 564 TRP A CZ2 1 ATOM 4486 C CZ3 . TRP A 1 564 ? 59.929 60.106 -30.769 1.00 11.46 ? 564 TRP A CZ3 1 ATOM 4487 C CH2 . TRP A 1 564 ? 61.054 59.281 -30.699 1.00 13.78 ? 564 TRP A CH2 1 ATOM 4488 N N . ARG A 1 565 ? 54.332 60.246 -28.820 1.00 8.33 ? 565 ARG A N 1 ATOM 4489 C CA . ARG A 1 565 ? 53.128 61.066 -28.882 1.00 9.29 ? 565 ARG A CA 1 ATOM 4490 C C . ARG A 1 565 ? 53.404 62.359 -29.604 1.00 7.88 ? 565 ARG A C 1 ATOM 4491 O O . ARG A 1 565 ? 54.449 62.997 -29.388 1.00 9.30 ? 565 ARG A O 1 ATOM 4492 C CB . ARG A 1 565 ? 52.601 61.382 -27.428 1.00 10.15 ? 565 ARG A CB 1 ATOM 4493 C CG . ARG A 1 565 ? 51.309 62.222 -27.467 1.00 10.67 ? 565 ARG A CG 1 ATOM 4494 C CD . ARG A 1 565 ? 50.458 62.213 -26.141 1.00 14.69 ? 565 ARG A CD 1 ATOM 4495 N NE . ARG A 1 565 ? 51.251 62.495 -24.971 1.00 14.15 ? 565 ARG A NE 1 ATOM 4496 C CZ . ARG A 1 565 ? 50.724 63.040 -23.859 1.00 10.71 ? 565 ARG A CZ 1 ATOM 4497 N NH1 . ARG A 1 565 ? 49.416 63.400 -23.802 1.00 10.89 ? 565 ARG A NH1 1 ATOM 4498 N NH2 . ARG A 1 565 ? 51.516 63.172 -22.816 1.00 10.33 ? 565 ARG A NH2 1 ATOM 4499 N N . GLU A 1 566 ? 52.475 62.722 -30.475 1.00 9.02 ? 566 GLU A N 1 ATOM 4500 C CA . GLU A 1 566 ? 52.463 64.067 -31.100 1.00 10.28 ? 566 GLU A CA 1 ATOM 4501 C C . GLU A 1 566 ? 51.323 64.869 -30.502 1.00 10.15 ? 566 GLU A C 1 ATOM 4502 O O . GLU A 1 566 ? 50.262 64.356 -30.231 1.00 11.28 ? 566 GLU A O 1 ATOM 4503 C CB . GLU A 1 566 ? 52.201 63.958 -32.592 1.00 12.42 ? 566 GLU A CB 1 ATOM 4504 C CG . GLU A 1 566 ? 53.309 63.352 -33.352 1.00 13.92 ? 566 GLU A CG 1 ATOM 4505 C CD . GLU A 1 566 ? 52.993 63.309 -34.867 1.00 16.59 ? 566 GLU A CD 1 ATOM 4506 O OE1 . GLU A 1 566 ? 51.816 63.081 -35.257 1.00 21.77 ? 566 GLU A OE1 1 ATOM 4507 O OE2 . GLU A 1 566 ? 53.961 63.500 -35.612 1.00 23.07 ? 566 GLU A OE2 1 ATOM 4508 N N . GLN A 1 567 ? 51.561 66.155 -30.266 1.00 8.59 ? 567 GLN A N 1 ATOM 4509 C CA . GLN A 1 567 ? 50.508 67.037 -29.752 1.00 8.23 ? 567 GLN A CA 1 ATOM 4510 C C . GLN A 1 567 ? 50.875 68.450 -30.170 1.00 8.11 ? 567 GLN A C 1 ATOM 4511 O O . GLN A 1 567 ? 52.086 68.806 -30.212 1.00 8.19 ? 567 GLN A O 1 ATOM 4512 C CB . GLN A 1 567 ? 50.471 66.986 -28.231 1.00 9.46 ? 567 GLN A CB 1 ATOM 4513 C CG . GLN A 1 567 ? 49.310 67.790 -27.624 1.00 9.58 ? 567 GLN A CG 1 ATOM 4514 C CD . GLN A 1 567 ? 49.715 68.249 -26.228 1.00 14.24 ? 567 GLN A CD 1 ATOM 4515 O OE1 . GLN A 1 567 ? 49.715 67.452 -25.276 1.00 11.67 ? 567 GLN A OE1 1 ATOM 4516 N NE2 . GLN A 1 567 ? 50.155 69.518 -26.099 1.00 15.42 ? 567 GLN A NE2 1 ATOM 4517 N N . LEU A 1 568 ? 49.893 69.241 -30.587 1.00 9.39 ? 568 LEU A N 1 ATOM 4518 C CA . LEU A 1 568 ? 50.234 70.658 -30.838 1.00 8.17 ? 568 LEU A CA 1 ATOM 4519 C C . LEU A 1 568 ? 50.551 71.354 -29.531 1.00 8.18 ? 568 LEU A C 1 ATOM 4520 O O . LEU A 1 568 ? 49.899 71.104 -28.465 1.00 9.24 ? 568 LEU A O 1 ATOM 4521 C CB . LEU A 1 568 ? 49.068 71.441 -31.458 1.00 11.00 ? 568 LEU A CB 1 ATOM 4522 C CG . LEU A 1 568 ? 48.574 71.008 -32.837 1.00 11.61 ? 568 LEU A CG 1 ATOM 4523 C CD1 . LEU A 1 568 ? 47.664 72.121 -33.415 1.00 13.67 ? 568 LEU A CD1 1 ATOM 4524 C CD2 . LEU A 1 568 ? 49.725 70.858 -33.768 1.00 14.06 ? 568 LEU A CD2 1 ATOM 4525 N N . VAL A 1 569 ? 51.538 72.209 -29.551 1.00 7.59 ? 569 VAL A N 1 ATOM 4526 C CA . VAL A 1 569 ? 51.926 72.999 -28.389 1.00 8.30 ? 569 VAL A CA 1 ATOM 4527 C C . VAL A 1 569 ? 52.005 74.451 -28.811 1.00 8.41 ? 569 VAL A C 1 ATOM 4528 O O . VAL A 1 569 ? 52.264 74.774 -29.988 1.00 9.70 ? 569 VAL A O 1 ATOM 4529 C CB . VAL A 1 569 ? 53.319 72.593 -27.800 1.00 7.33 ? 569 VAL A CB 1 ATOM 4530 C CG1 . VAL A 1 569 ? 53.200 71.175 -27.157 1.00 10.19 ? 569 VAL A CG1 1 ATOM 4531 C CG2 . VAL A 1 569 ? 54.424 72.597 -28.919 1.00 8.67 ? 569 VAL A CG2 1 ATOM 4532 N N . ASP A 1 570 ? 51.745 75.341 -27.877 1.00 8.23 ? 570 ASP A N 1 ATOM 4533 C CA . ASP A 1 570 ? 51.812 76.770 -28.200 1.00 9.42 ? 570 ASP A CA 1 ATOM 4534 C C . ASP A 1 570 ? 52.634 77.519 -27.185 1.00 10.59 ? 570 ASP A C 1 ATOM 4535 O O . ASP A 1 570 ? 52.715 77.160 -25.989 1.00 11.44 ? 570 ASP A O 1 ATOM 4536 C CB . ASP A 1 570 ? 50.416 77.386 -28.348 1.00 10.76 ? 570 ASP A CB 1 ATOM 4537 C CG . ASP A 1 570 ? 49.694 77.503 -27.043 1.00 16.84 ? 570 ASP A CG 1 ATOM 4538 O OD1 . ASP A 1 570 ? 49.610 76.512 -26.306 1.00 22.55 ? 570 ASP A OD1 1 ATOM 4539 O OD2 . ASP A 1 570 ? 49.201 78.588 -26.724 1.00 24.60 ? 570 ASP A OD2 1 ATOM 4540 N N . PHE A 1 571 ? 53.261 78.597 -27.652 1.00 8.01 ? 571 PHE A N 1 ATOM 4541 C CA . PHE A 1 571 ? 54.055 79.485 -26.790 1.00 9.00 ? 571 PHE A CA 1 ATOM 4542 C C . PHE A 1 571 ? 53.706 80.941 -27.186 1.00 8.54 ? 571 PHE A C 1 ATOM 4543 O O . PHE A 1 571 ? 53.369 81.195 -28.338 1.00 10.12 ? 571 PHE A O 1 ATOM 4544 C CB . PHE A 1 571 ? 55.577 79.309 -27.036 1.00 9.32 ? 571 PHE A CB 1 ATOM 4545 C CG . PHE A 1 571 ? 56.080 77.944 -26.644 1.00 6.90 ? 571 PHE A CG 1 ATOM 4546 C CD1 . PHE A 1 571 ? 56.067 76.871 -27.525 1.00 8.36 ? 571 PHE A CD1 1 ATOM 4547 C CD2 . PHE A 1 571 ? 56.525 77.783 -25.347 1.00 8.75 ? 571 PHE A CD2 1 ATOM 4548 C CE1 . PHE A 1 571 ? 56.510 75.603 -27.077 1.00 9.08 ? 571 PHE A CE1 1 ATOM 4549 C CE2 . PHE A 1 571 ? 56.957 76.529 -24.892 1.00 8.53 ? 571 PHE A CE2 1 ATOM 4550 C CZ . PHE A 1 571 ? 56.949 75.436 -25.774 1.00 9.16 ? 571 PHE A CZ 1 ATOM 4551 N N . TYR A 1 572 ? 53.824 81.838 -26.221 1.00 7.75 ? 572 TYR A N 1 ATOM 4552 C CA . TYR A 1 572 ? 53.694 83.273 -26.523 1.00 8.31 ? 572 TYR A CA 1 ATOM 4553 C C . TYR A 1 572 ? 55.086 83.746 -26.927 1.00 10.20 ? 572 TYR A C 1 ATOM 4554 O O . TYR A 1 572 ? 56.075 83.449 -26.262 1.00 9.18 ? 572 TYR A O 1 ATOM 4555 C CB . TYR A 1 572 ? 53.254 84.054 -25.282 1.00 10.64 ? 572 TYR A CB 1 ATOM 4556 C CG . TYR A 1 572 ? 51.818 83.912 -24.855 1.00 12.23 ? 572 TYR A CG 1 ATOM 4557 C CD1 . TYR A 1 572 ? 50.867 83.249 -25.613 1.00 11.64 ? 572 TYR A CD1 1 ATOM 4558 C CD2 . TYR A 1 572 ? 51.423 84.473 -23.653 1.00 22.54 ? 572 TYR A CD2 1 ATOM 4559 C CE1 . TYR A 1 572 ? 49.529 83.148 -25.189 1.00 13.12 ? 572 TYR A CE1 1 ATOM 4560 C CE2 . TYR A 1 572 ? 50.107 84.391 -23.229 1.00 22.07 ? 572 TYR A CE2 1 ATOM 4561 C CZ . TYR A 1 572 ? 49.182 83.742 -24.000 1.00 18.76 ? 572 TYR A CZ 1 ATOM 4562 O OH . TYR A 1 572 ? 47.856 83.741 -23.560 1.00 19.38 ? 572 TYR A OH 1 ATOM 4563 N N . VAL A 1 573 ? 55.130 84.574 -27.959 1.00 9.30 ? 573 VAL A N 1 ATOM 4564 C CA . VAL A 1 573 ? 56.384 85.145 -28.515 1.00 9.33 ? 573 VAL A CA 1 ATOM 4565 C C . VAL A 1 573 ? 56.166 86.618 -28.815 1.00 8.97 ? 573 VAL A C 1 ATOM 4566 O O . VAL A 1 573 ? 55.038 87.052 -29.109 1.00 10.51 ? 573 VAL A O 1 ATOM 4567 C CB . VAL A 1 573 ? 56.843 84.415 -29.772 1.00 9.52 ? 573 VAL A CB 1 ATOM 4568 C CG1 . VAL A 1 573 ? 57.340 83.013 -29.443 1.00 12.83 ? 573 VAL A CG1 1 ATOM 4569 C CG2 . VAL A 1 573 ? 55.748 84.305 -30.790 1.00 12.82 ? 573 VAL A CG2 1 ATOM 4570 N N . SER A 1 574 ? 57.268 87.376 -28.765 1.00 9.66 ? 574 SER A N 1 ATOM 4571 C CA . SER A 1 574 ? 57.158 88.842 -28.943 1.00 9.93 ? 574 SER A CA 1 ATOM 4572 C C . SER A 1 574 ? 57.186 89.326 -30.375 1.00 11.74 ? 574 SER A C 1 ATOM 4573 O O . SER A 1 574 ? 57.184 90.564 -30.581 1.00 16.10 ? 574 SER A O 1 ATOM 4574 C CB . SER A 1 574 ? 58.258 89.513 -28.164 1.00 12.93 ? 574 SER A CB 1 ATOM 4575 O OG . SER A 1 574 ? 59.552 89.170 -28.651 1.00 11.90 ? 574 SER A OG 1 ATOM 4576 N N . SER A 1 575 ? 57.179 88.436 -31.352 1.00 12.13 ? 575 SER A N 1 ATOM 4577 C CA . SER A 1 575 ? 57.105 88.767 -32.763 1.00 13.36 ? 575 SER A CA 1 ATOM 4578 C C . SER A 1 575 ? 56.310 87.729 -33.487 1.00 13.91 ? 575 SER A C 1 ATOM 4579 O O . SER A 1 575 ? 56.332 86.547 -33.091 1.00 12.58 ? 575 SER A O 1 ATOM 4580 C CB . SER A 1 575 ? 58.523 88.737 -33.369 1.00 15.68 ? 575 SER A CB 1 ATOM 4581 O OG . SER A 1 575 ? 58.521 88.840 -34.788 1.00 14.34 ? 575 SER A OG 1 ATOM 4582 N N . PRO A 1 576 ? 55.603 88.108 -34.552 1.00 13.33 ? 576 PRO A N 1 ATOM 4583 C CA . PRO A 1 576 ? 54.861 87.098 -35.297 1.00 11.58 ? 576 PRO A CA 1 ATOM 4584 C C . PRO A 1 576 ? 55.791 86.373 -36.297 1.00 10.81 ? 576 PRO A C 1 ATOM 4585 O O . PRO A 1 576 ? 55.410 85.370 -36.905 1.00 12.77 ? 576 PRO A O 1 ATOM 4586 C CB . PRO A 1 576 ? 53.783 87.892 -36.044 1.00 14.57 ? 576 PRO A CB 1 ATOM 4587 C CG . PRO A 1 576 ? 54.482 89.269 -36.234 1.00 17.91 ? 576 PRO A CG 1 ATOM 4588 C CD . PRO A 1 576 ? 55.357 89.485 -35.046 1.00 14.08 ? 576 PRO A CD 1 ATOM 4589 N N . PHE A 1 577 ? 57.029 86.883 -36.496 1.00 11.60 ? 577 PHE A N 1 ATOM 4590 C CA . PHE A 1 577 ? 57.913 86.320 -37.513 1.00 11.70 ? 577 PHE A CA 1 ATOM 4591 C C . PHE A 1 577 ? 58.888 85.369 -36.855 1.00 12.85 ? 577 PHE A C 1 ATOM 4592 O O . PHE A 1 577 ? 60.036 85.684 -36.626 1.00 13.32 ? 577 PHE A O 1 ATOM 4593 C CB . PHE A 1 577 ? 58.650 87.461 -38.244 1.00 13.41 ? 577 PHE A CB 1 ATOM 4594 C CG . PHE A 1 577 ? 57.722 88.471 -38.837 1.00 16.80 ? 577 PHE A CG 1 ATOM 4595 C CD1 . PHE A 1 577 ? 56.686 88.053 -39.635 1.00 14.77 ? 577 PHE A CD1 1 ATOM 4596 C CD2 . PHE A 1 577 ? 57.924 89.821 -38.616 1.00 22.01 ? 577 PHE A CD2 1 ATOM 4597 C CE1 . PHE A 1 577 ? 55.830 88.981 -40.242 1.00 20.35 ? 577 PHE A CE1 1 ATOM 4598 C CE2 . PHE A 1 577 ? 57.073 90.764 -39.215 1.00 24.74 ? 577 PHE A CE2 1 ATOM 4599 C CZ . PHE A 1 577 ? 56.046 90.335 -40.016 1.00 21.01 ? 577 PHE A CZ 1 ATOM 4600 N N . VAL A 1 578 ? 58.363 84.182 -36.563 1.00 11.17 ? 578 VAL A N 1 ATOM 4601 C CA . VAL A 1 578 ? 59.135 83.166 -35.821 1.00 11.87 ? 578 VAL A CA 1 ATOM 4602 C C . VAL A 1 578 ? 58.988 81.830 -36.523 1.00 11.88 ? 578 VAL A C 1 ATOM 4603 O O . VAL A 1 578 ? 57.951 81.513 -37.060 1.00 12.05 ? 578 VAL A O 1 ATOM 4604 C CB . VAL A 1 578 ? 58.585 83.064 -34.361 1.00 12.37 ? 578 VAL A CB 1 ATOM 4605 C CG1 . VAL A 1 578 ? 59.320 81.926 -33.573 1.00 12.63 ? 578 VAL A CG1 1 ATOM 4606 C CG2 . VAL A 1 578 ? 58.827 84.333 -33.630 1.00 12.49 ? 578 VAL A CG2 1 ATOM 4607 N N . SER A 1 579 ? 60.113 81.131 -36.597 1.00 12.99 ? 579 SER A N 1 ATOM 4608 C CA . SER A 1 579 ? 60.065 79.810 -37.181 1.00 13.66 ? 579 SER A CA 1 ATOM 4609 C C . SER A 1 579 ? 60.610 78.779 -36.197 1.00 10.01 ? 579 SER A C 1 ATOM 4610 O O . SER A 1 579 ? 61.394 79.092 -35.302 1.00 11.28 ? 579 SER A O 1 ATOM 4611 C CB . SER A 1 579 ? 60.734 79.725 -38.534 1.00 21.06 ? 579 SER A CB 1 ATOM 4612 O OG . SER A 1 579 ? 61.971 80.280 -38.467 1.00 23.97 ? 579 SER A OG 1 ATOM 4613 N N . VAL A 1 580 ? 60.194 77.564 -36.431 1.00 8.45 ? 580 VAL A N 1 ATOM 4614 C CA . VAL A 1 580 ? 60.545 76.470 -35.533 1.00 8.17 ? 580 VAL A CA 1 ATOM 4615 C C . VAL A 1 580 ? 61.421 75.451 -36.254 1.00 8.96 ? 580 VAL A C 1 ATOM 4616 O O . VAL A 1 580 ? 61.160 75.081 -37.413 1.00 10.28 ? 580 VAL A O 1 ATOM 4617 C CB . VAL A 1 580 ? 59.277 75.777 -35.049 1.00 8.06 ? 580 VAL A CB 1 ATOM 4618 C CG1 . VAL A 1 580 ? 59.610 74.633 -34.064 1.00 9.95 ? 580 VAL A CG1 1 ATOM 4619 C CG2 . VAL A 1 580 ? 58.310 76.802 -34.386 1.00 10.14 ? 580 VAL A CG2 1 ATOM 4620 N N . THR A 1 581 ? 62.396 74.963 -35.510 1.00 8.35 ? 581 THR A N 1 ATOM 4621 C CA . THR A 1 581 ? 63.261 73.864 -35.981 1.00 8.57 ? 581 THR A CA 1 ATOM 4622 C C . THR A 1 581 ? 63.448 72.844 -34.841 1.00 9.71 ? 581 THR A C 1 ATOM 4623 O O . THR A 1 581 ? 63.243 73.143 -33.637 1.00 9.56 ? 581 THR A O 1 ATOM 4624 C CB . THR A 1 581 ? 64.679 74.357 -36.384 1.00 9.89 ? 581 THR A CB 1 ATOM 4625 O OG1 . THR A 1 581 ? 65.220 75.244 -35.402 1.00 12.60 ? 581 THR A OG1 1 ATOM 4626 C CG2 . THR A 1 581 ? 64.589 75.150 -37.732 1.00 11.14 ? 581 THR A CG2 1 ATOM 4627 N N . ASP A 1 582 ? 63.738 71.595 -35.206 1.00 10.94 ? 582 ASP A N 1 ATOM 4628 C CA . ASP A 1 582 ? 64.177 70.567 -34.230 1.00 12.58 ? 582 ASP A CA 1 ATOM 4629 C C . ASP A 1 582 ? 65.689 70.687 -33.977 1.00 11.93 ? 582 ASP A C 1 ATOM 4630 O O . ASP A 1 582 ? 66.296 71.569 -34.526 1.00 14.36 ? 582 ASP A O 1 ATOM 4631 C CB . ASP A 1 582 ? 63.728 69.139 -34.598 1.00 17.09 ? 582 ASP A CB 1 ATOM 4632 C CG . ASP A 1 582 ? 64.360 68.603 -35.878 1.00 14.45 ? 582 ASP A CG 1 ATOM 4633 O OD1 . ASP A 1 582 ? 65.403 69.098 -36.298 1.00 15.23 ? 582 ASP A OD1 1 ATOM 4634 O OD2 . ASP A 1 582 ? 63.782 67.672 -36.430 1.00 19.01 ? 582 ASP A OD2 1 ATOM 4635 N N . LEU A 1 583 ? 66.303 69.872 -33.109 1.00 21.15 ? 583 LEU A N 1 ATOM 4636 C CA . LEU A 1 583 ? 67.726 70.168 -32.896 1.00 23.25 ? 583 LEU A CA 1 ATOM 4637 C C . LEU A 1 583 ? 68.659 69.620 -33.981 1.00 23.88 ? 583 LEU A C 1 ATOM 4638 O O . LEU A 1 583 ? 69.876 69.740 -33.839 1.00 26.87 ? 583 LEU A O 1 ATOM 4639 C CB . LEU A 1 583 ? 68.203 69.773 -31.458 1.00 22.20 ? 583 LEU A CB 1 ATOM 4640 C CG . LEU A 1 583 ? 69.083 70.806 -30.698 1.00 20.05 ? 583 LEU A CG 1 ATOM 4641 C CD1 . LEU A 1 583 ? 68.352 72.104 -30.654 1.00 25.91 ? 583 LEU A CD1 1 ATOM 4642 C CD2 . LEU A 1 583 ? 69.475 70.401 -29.232 1.00 22.06 ? 583 LEU A CD2 1 ATOM 4643 N N . ALA A 1 584 ? 68.088 69.047 -35.066 1.00 18.47 ? 584 ALA A N 1 ATOM 4644 C CA . ALA A 1 584 ? 68.928 68.675 -36.219 1.00 13.93 ? 584 ALA A CA 1 ATOM 4645 C C . ALA A 1 584 ? 68.705 69.775 -37.217 1.00 12.96 ? 584 ALA A C 1 ATOM 4646 O O . ALA A 1 584 ? 69.105 69.696 -38.395 1.00 12.86 ? 584 ALA A O 1 ATOM 4647 C CB . ALA A 1 584 ? 68.518 67.377 -36.834 1.00 15.94 ? 584 ALA A CB 1 ATOM 4648 N N . ASN A 1 585 ? 68.065 70.858 -36.775 1.00 12.74 ? 585 ASN A N 1 ATOM 4649 C CA . ASN A 1 585 ? 67.798 71.978 -37.636 1.00 12.06 ? 585 ASN A CA 1 ATOM 4650 C C . ASN A 1 585 ? 66.832 71.770 -38.771 1.00 12.07 ? 585 ASN A C 1 ATOM 4651 O O . ASN A 1 585 ? 66.820 72.559 -39.758 1.00 16.53 ? 585 ASN A O 1 ATOM 4652 C CB . ASN A 1 585 ? 69.072 72.621 -38.160 1.00 16.74 ? 585 ASN A CB 1 ATOM 4653 C CG . ASN A 1 585 ? 69.270 73.940 -37.550 1.00 30.86 ? 585 ASN A CG 1 ATOM 4654 O OD1 . ASN A 1 585 ? 68.549 74.929 -37.872 1.00 24.03 ? 585 ASN A OD1 1 ATOM 4655 N ND2 . ASN A 1 585 ? 70.174 73.983 -36.575 1.00 31.49 ? 585 ASN A ND2 1 ATOM 4656 N N . ASN A 1 586 ? 66.000 70.749 -38.672 1.00 9.50 ? 586 ASN A N 1 ATOM 4657 C CA . ASN A 1 586 ? 64.966 70.465 -39.673 1.00 12.24 ? 586 ASN A CA 1 ATOM 4658 C C . ASN A 1 586 ? 63.791 71.431 -39.366 1.00 12.92 ? 586 ASN A C 1 ATOM 4659 O O . ASN A 1 586 ? 63.364 71.582 -38.213 1.00 11.82 ? 586 ASN A O 1 ATOM 4660 C CB . ASN A 1 586 ? 64.383 69.070 -39.518 1.00 14.34 ? 586 ASN A CB 1 ATOM 4661 C CG . ASN A 1 586 ? 65.433 67.962 -39.581 1.00 17.38 ? 586 ASN A CG 1 ATOM 4662 O OD1 . ASN A 1 586 ? 66.277 67.999 -40.456 1.00 18.36 ? 586 ASN A OD1 1 ATOM 4663 N ND2 . ASN A 1 586 ? 65.375 66.977 -38.659 1.00 16.06 ? 586 ASN A ND2 1 ATOM 4664 N N . PRO A 1 587 ? 63.249 72.081 -40.377 1.00 11.98 ? 587 PRO A N 1 ATOM 4665 C CA . PRO A 1 587 ? 62.114 72.991 -40.176 1.00 11.00 ? 587 PRO A CA 1 ATOM 4666 C C . PRO A 1 587 ? 60.899 72.200 -39.727 1.00 11.00 ? 587 PRO A C 1 ATOM 4667 O O . PRO A 1 587 ? 60.671 71.029 -40.103 1.00 13.20 ? 587 PRO A O 1 ATOM 4668 C CB . PRO A 1 587 ? 61.897 73.640 -41.561 1.00 14.60 ? 587 PRO A CB 1 ATOM 4669 C CG . PRO A 1 587 ? 62.562 72.678 -42.523 1.00 22.14 ? 587 PRO A CG 1 ATOM 4670 C CD . PRO A 1 587 ? 63.768 72.097 -41.765 1.00 14.20 ? 587 PRO A CD 1 ATOM 4671 N N . VAL A 1 588 ? 60.086 72.855 -38.882 1.00 10.15 ? 588 VAL A N 1 ATOM 4672 C CA . VAL A 1 588 ? 58.857 72.265 -38.370 1.00 10.11 ? 588 VAL A CA 1 ATOM 4673 C C . VAL A 1 588 ? 57.739 73.266 -38.744 1.00 10.25 ? 588 VAL A C 1 ATOM 4674 O O . VAL A 1 588 ? 57.884 74.472 -38.507 1.00 11.13 ? 588 VAL A O 1 ATOM 4675 C CB . VAL A 1 588 ? 58.917 72.159 -36.825 1.00 10.54 ? 588 VAL A CB 1 ATOM 4676 C CG1 . VAL A 1 588 ? 57.619 71.654 -36.298 1.00 12.63 ? 588 VAL A CG1 1 ATOM 4677 C CG2 . VAL A 1 588 ? 60.061 71.161 -36.403 1.00 12.28 ? 588 VAL A CG2 1 ATOM 4678 N N . GLU A 1 589 ? 56.692 72.757 -39.370 1.00 10.75 ? 589 GLU A N 1 ATOM 4679 C CA . GLU A 1 589 ? 55.570 73.625 -39.781 1.00 10.55 ? 589 GLU A CA 1 ATOM 4680 C C . GLU A 1 589 ? 54.923 74.284 -38.556 1.00 10.61 ? 589 GLU A C 1 ATOM 4681 O O . GLU A 1 589 ? 54.689 73.584 -37.514 1.00 11.84 ? 589 GLU A O 1 ATOM 4682 C CB . GLU A 1 589 ? 54.519 72.804 -40.515 1.00 13.44 ? 589 GLU A CB 1 ATOM 4683 C CG . GLU A 1 589 ? 53.414 73.728 -41.073 1.00 22.90 ? 589 GLU A CG 1 ATOM 4684 C CD . GLU A 1 589 ? 52.267 73.018 -41.793 1.00 31.63 ? 589 GLU A CD 1 ATOM 4685 O OE1 . GLU A 1 589 ? 52.391 71.804 -42.060 1.00 32.46 ? 589 GLU A OE1 1 ATOM 4686 O OE2 . GLU A 1 589 ? 51.222 73.691 -42.088 1.00 29.23 ? 589 GLU A OE2 1 ATOM 4687 N N . ALA A 1 590 ? 54.664 75.573 -38.613 1.00 9.17 ? 590 ALA A N 1 ATOM 4688 C CA . ALA A 1 590 ? 54.109 76.273 -37.469 1.00 9.01 ? 590 ALA A CA 1 ATOM 4689 C C . ALA A 1 590 ? 52.990 77.195 -37.917 1.00 10.69 ? 590 ALA A C 1 ATOM 4690 O O . ALA A 1 590 ? 52.900 77.524 -39.140 1.00 10.77 ? 590 ALA A O 1 ATOM 4691 C CB . ALA A 1 590 ? 55.173 77.102 -36.764 1.00 10.65 ? 590 ALA A CB 1 ATOM 4692 N N . GLN A 1 591 ? 52.165 77.621 -36.979 1.00 9.78 ? 591 GLN A N 1 ATOM 4693 C CA . GLN A 1 591 ? 51.080 78.575 -37.239 1.00 8.15 ? 591 GLN A CA 1 ATOM 4694 C C . GLN A 1 591 ? 51.174 79.648 -36.187 1.00 8.93 ? 591 GLN A C 1 ATOM 4695 O O . GLN A 1 591 ? 51.411 79.371 -34.995 1.00 10.38 ? 591 GLN A O 1 ATOM 4696 C CB . GLN A 1 591 ? 49.716 77.886 -37.128 1.00 8.95 ? 591 GLN A CB 1 ATOM 4697 C CG . GLN A 1 591 ? 48.550 78.909 -37.180 1.00 9.40 ? 591 GLN A CG 1 ATOM 4698 C CD . GLN A 1 591 ? 47.212 78.184 -36.989 1.00 9.76 ? 591 GLN A CD 1 ATOM 4699 O OE1 . GLN A 1 591 ? 46.983 77.108 -37.550 1.00 10.41 ? 591 GLN A OE1 1 ATOM 4700 N NE2 . GLN A 1 591 ? 46.332 78.745 -36.162 1.00 10.97 ? 591 GLN A NE2 1 ATOM 4701 N N . VAL A 1 592 ? 51.036 80.929 -36.559 1.00 9.08 ? 592 VAL A N 1 ATOM 4702 C CA . VAL A 1 592 ? 50.989 82.033 -35.603 1.00 9.50 ? 592 VAL A CA 1 ATOM 4703 C C . VAL A 1 592 ? 49.569 82.566 -35.634 1.00 8.33 ? 592 VAL A C 1 ATOM 4704 O O . VAL A 1 592 ? 48.939 82.646 -36.708 1.00 10.79 ? 592 VAL A O 1 ATOM 4705 C CB . VAL A 1 592 ? 52.047 83.111 -35.985 1.00 9.02 ? 592 VAL A CB 1 ATOM 4706 C CG1 . VAL A 1 592 ? 51.848 84.375 -35.169 1.00 11.57 ? 592 VAL A CG1 1 ATOM 4707 C CG2 . VAL A 1 592 ? 53.442 82.581 -35.678 1.00 10.72 ? 592 VAL A CG2 1 ATOM 4708 N N . SER A 1 593 ? 49.040 82.803 -34.440 1.00 11.05 ? 593 SER A N 1 ATOM 4709 C CA . SER A 1 593 ? 47.699 83.345 -34.203 1.00 10.74 ? 593 SER A CA 1 ATOM 4710 C C . SER A 1 593 ? 47.852 84.521 -33.262 1.00 10.37 ? 593 SER A C 1 ATOM 4711 O O . SER A 1 593 ? 48.845 84.621 -32.558 1.00 12.15 ? 593 SER A O 1 ATOM 4712 C CB . SER A 1 593 ? 46.825 82.289 -33.510 1.00 12.31 ? 593 SER A CB 1 ATOM 4713 O OG . SER A 1 593 ? 46.505 81.208 -34.368 1.00 13.07 ? 593 SER A OG 1 ATOM 4714 N N . PRO A 1 594 ? 46.871 85.414 -33.207 1.00 10.50 ? 594 PRO A N 1 ATOM 4715 C CA . PRO A 1 594 ? 46.975 86.492 -32.215 1.00 10.02 ? 594 PRO A CA 1 ATOM 4716 C C . PRO A 1 594 ? 46.735 86.029 -30.767 1.00 9.58 ? 594 PRO A C 1 ATOM 4717 O O . PRO A 1 594 ? 46.291 84.868 -30.530 1.00 10.50 ? 594 PRO A O 1 ATOM 4718 C CB . PRO A 1 594 ? 45.833 87.458 -32.605 1.00 11.29 ? 594 PRO A CB 1 ATOM 4719 C CG . PRO A 1 594 ? 45.425 87.010 -34.007 1.00 11.06 ? 594 PRO A CG 1 ATOM 4720 C CD . PRO A 1 594 ? 45.664 85.558 -34.056 1.00 9.63 ? 594 PRO A CD 1 ATOM 4721 N N . VAL A 1 595 ? 47.048 86.873 -29.781 1.00 9.74 ? 595 VAL A N 1 ATOM 4722 C CA . VAL A 1 595 ? 46.702 86.558 -28.415 1.00 10.55 ? 595 VAL A CA 1 ATOM 4723 C C . VAL A 1 595 ? 45.433 87.371 -28.149 1.00 10.19 ? 595 VAL A C 1 ATOM 4724 O O . VAL A 1 595 ? 45.441 88.616 -28.225 1.00 12.13 ? 595 VAL A O 1 ATOM 4725 C CB . VAL A 1 595 ? 47.800 86.959 -27.408 1.00 11.09 ? 595 VAL A CB 1 ATOM 4726 C CG1 . VAL A 1 595 ? 47.257 86.820 -25.987 1.00 12.64 ? 595 VAL A CG1 1 ATOM 4727 C CG2 . VAL A 1 595 ? 49.025 86.067 -27.650 1.00 11.66 ? 595 VAL A CG2 1 ATOM 4728 N N . TRP A 1 596 ? 44.337 86.662 -27.906 1.00 10.68 ? 596 TRP A N 1 ATOM 4729 C CA . TRP A 1 596 ? 43.021 87.267 -27.741 1.00 10.81 ? 596 TRP A CA 1 ATOM 4730 C C . TRP A 1 596 ? 42.623 87.172 -26.271 1.00 11.38 ? 596 TRP A C 1 ATOM 4731 O O . TRP A 1 596 ? 42.659 86.103 -25.689 1.00 15.12 ? 596 TRP A O 1 ATOM 4732 C CB . TRP A 1 596 ? 41.990 86.499 -28.577 1.00 10.47 ? 596 TRP A CB 1 ATOM 4733 C CG . TRP A 1 596 ? 42.102 86.691 -30.055 1.00 10.78 ? 596 TRP A CG 1 ATOM 4734 C CD1 . TRP A 1 596 ? 42.503 85.771 -30.975 1.00 9.59 ? 596 TRP A CD1 1 ATOM 4735 C CD2 . TRP A 1 596 ? 41.782 87.875 -30.786 1.00 10.07 ? 596 TRP A CD2 1 ATOM 4736 N NE1 . TRP A 1 596 ? 42.458 86.311 -32.233 1.00 11.70 ? 596 TRP A NE1 1 ATOM 4737 C CE2 . TRP A 1 596 ? 42.021 87.604 -32.141 1.00 11.42 ? 596 TRP A CE2 1 ATOM 4738 C CE3 . TRP A 1 596 ? 41.321 89.141 -30.422 1.00 10.67 ? 596 TRP A CE3 1 ATOM 4739 C CZ2 . TRP A 1 596 ? 41.813 88.550 -33.132 1.00 12.34 ? 596 TRP A CZ2 1 ATOM 4740 C CZ3 . TRP A 1 596 ? 41.122 90.077 -31.407 1.00 11.42 ? 596 TRP A CZ3 1 ATOM 4741 C CH2 . TRP A 1 596 ? 41.362 89.776 -32.744 1.00 13.44 ? 596 TRP A CH2 1 ATOM 4742 N N . SER A 1 597 ? 42.228 88.289 -25.683 1.00 12.02 ? 597 SER A N 1 ATOM 4743 C CA . SER A 1 597 ? 41.725 88.298 -24.320 1.00 14.59 ? 597 SER A CA 1 ATOM 4744 C C . SER A 1 597 ? 40.326 88.894 -24.273 1.00 17.49 ? 597 SER A C 1 ATOM 4745 O O . SER A 1 597 ? 40.048 89.904 -24.917 1.00 19.44 ? 597 SER A O 1 ATOM 4746 C CB A SER A 1 597 ? 42.644 88.993 -23.317 0.50 21.03 ? 597 SER A CB 1 ATOM 4747 C CB B SER A 1 597 ? 42.542 89.254 -23.450 0.50 22.19 ? 597 SER A CB 1 ATOM 4748 O OG A SER A 1 597 ? 42.605 90.359 -23.631 0.50 25.45 ? 597 SER A OG 1 ATOM 4749 O OG B SER A 1 597 ? 43.925 89.086 -23.677 0.50 34.87 ? 597 SER A OG 1 ATOM 4750 N N . TRP A 1 598 ? 39.451 88.266 -23.503 1.00 13.13 ? 598 TRP A N 1 ATOM 4751 C CA . TRP A 1 598 ? 38.057 88.681 -23.450 1.00 11.75 ? 598 TRP A CA 1 ATOM 4752 C C . TRP A 1 598 ? 37.811 89.578 -22.256 1.00 13.52 ? 598 TRP A C 1 ATOM 4753 O O . TRP A 1 598 ? 38.342 89.361 -21.181 1.00 18.25 ? 598 TRP A O 1 ATOM 4754 C CB . TRP A 1 598 ? 37.124 87.470 -23.388 1.00 13.42 ? 598 TRP A CB 1 ATOM 4755 C CG . TRP A 1 598 ? 37.053 86.731 -24.671 1.00 11.20 ? 598 TRP A CG 1 ATOM 4756 C CD1 . TRP A 1 598 ? 37.957 85.839 -25.145 1.00 12.01 ? 598 TRP A CD1 1 ATOM 4757 C CD2 . TRP A 1 598 ? 36.030 86.831 -25.659 1.00 10.50 ? 598 TRP A CD2 1 ATOM 4758 N NE1 . TRP A 1 598 ? 37.562 85.366 -26.365 1.00 11.50 ? 598 TRP A NE1 1 ATOM 4759 C CE2 . TRP A 1 598 ? 36.377 85.958 -26.704 1.00 9.69 ? 598 TRP A CE2 1 ATOM 4760 C CE3 . TRP A 1 598 ? 34.842 87.560 -25.755 1.00 11.46 ? 598 TRP A CE3 1 ATOM 4761 C CZ2 . TRP A 1 598 ? 35.587 85.798 -27.835 1.00 10.83 ? 598 TRP A CZ2 1 ATOM 4762 C CZ3 . TRP A 1 598 ? 34.054 87.400 -26.878 1.00 10.12 ? 598 TRP A CZ3 1 ATOM 4763 C CH2 . TRP A 1 598 ? 34.432 86.529 -27.905 1.00 12.65 ? 598 TRP A CH2 1 ATOM 4764 N N . HIS A 1 599 ? 36.987 90.587 -22.461 1.00 15.58 ? 599 HIS A N 1 ATOM 4765 C CA . HIS A 1 599 ? 36.751 91.571 -21.448 1.00 19.86 ? 599 HIS A CA 1 ATOM 4766 C C . HIS A 1 599 ? 35.290 91.783 -21.271 1.00 19.14 ? 599 HIS A C 1 ATOM 4767 O O . HIS A 1 599 ? 34.556 91.881 -22.231 1.00 18.43 ? 599 HIS A O 1 ATOM 4768 C CB . HIS A 1 599 ? 37.507 92.832 -21.799 1.00 23.45 ? 599 HIS A CB 1 ATOM 4769 C CG . HIS A 1 599 ? 38.981 92.600 -21.830 1.00 30.32 ? 599 HIS A CG 1 ATOM 4770 N ND1 . HIS A 1 599 ? 39.713 92.318 -20.695 1.00 34.65 ? 599 HIS A ND1 1 ATOM 4771 C CD2 . HIS A 1 599 ? 39.843 92.511 -22.864 1.00 34.85 ? 599 HIS A CD2 1 ATOM 4772 C CE1 . HIS A 1 599 ? 40.972 92.107 -21.031 1.00 33.80 ? 599 HIS A CE1 1 ATOM 4773 N NE2 . HIS A 1 599 ? 41.075 92.217 -22.340 1.00 32.49 ? 599 HIS A NE2 1 ATOM 4774 N N . HIS A 1 600 ? 34.847 91.765 -20.024 1.00 21.83 ? 600 HIS A N 1 ATOM 4775 C CA . HIS A 1 600 ? 33.515 92.237 -19.732 1.00 23.27 ? 600 HIS A CA 1 ATOM 4776 C C . HIS A 1 600 ? 33.546 93.745 -19.647 1.00 20.45 ? 600 HIS A C 1 ATOM 4777 O O . HIS A 1 600 ? 33.981 94.309 -18.650 1.00 25.96 ? 600 HIS A O 1 ATOM 4778 C CB . HIS A 1 600 ? 32.950 91.656 -18.447 1.00 27.82 ? 600 HIS A CB 1 ATOM 4779 C CG . HIS A 1 600 ? 31.620 92.233 -18.080 1.00 38.86 ? 600 HIS A CG 1 ATOM 4780 N ND1 . HIS A 1 600 ? 31.068 92.103 -16.824 1.00 41.92 ? 600 HIS A ND1 1 ATOM 4781 C CD2 . HIS A 1 600 ? 30.742 92.967 -18.804 1.00 40.96 ? 600 HIS A CD2 1 ATOM 4782 C CE1 . HIS A 1 600 ? 29.902 92.721 -16.794 1.00 41.03 ? 600 HIS A CE1 1 ATOM 4783 N NE2 . HIS A 1 600 ? 29.680 93.253 -17.983 1.00 45.58 ? 600 HIS A NE2 1 ATOM 4784 N N . ASP A 1 601 ? 33.098 94.380 -20.715 1.00 19.57 ? 601 ASP A N 1 ATOM 4785 C CA . ASP A 1 601 ? 33.217 95.816 -20.853 1.00 21.02 ? 601 ASP A CA 1 ATOM 4786 C C . ASP A 1 601 ? 32.079 96.505 -20.083 1.00 22.70 ? 601 ASP A C 1 ATOM 4787 O O . ASP A 1 601 ? 30.948 96.488 -20.539 1.00 22.03 ? 601 ASP A O 1 ATOM 4788 C CB . ASP A 1 601 ? 33.212 96.139 -22.343 1.00 22.61 ? 601 ASP A CB 1 ATOM 4789 C CG . ASP A 1 601 ? 33.574 97.568 -22.641 1.00 28.33 ? 601 ASP A CG 1 ATOM 4790 O OD1 . ASP A 1 601 ? 33.355 98.429 -21.761 1.00 26.05 ? 601 ASP A OD1 1 ATOM 4791 O OD2 . ASP A 1 601 ? 34.058 97.835 -23.766 1.00 30.47 ? 601 ASP A OD2 1 ATOM 4792 N N . THR A 1 602 ? 32.394 97.099 -18.921 1.00 25.57 ? 602 THR A N 1 ATOM 4793 C CA . THR A 1 602 ? 31.352 97.736 -18.114 1.00 27.47 ? 602 THR A CA 1 ATOM 4794 C C . THR A 1 602 ? 30.863 99.052 -18.675 1.00 26.14 ? 602 THR A C 1 ATOM 4795 O O . THR A 1 602 ? 29.879 99.596 -18.167 1.00 26.83 ? 602 THR A O 1 ATOM 4796 C CB . THR A 1 602 ? 31.756 97.967 -16.621 1.00 29.94 ? 602 THR A CB 1 ATOM 4797 O OG1 . THR A 1 602 ? 32.899 98.843 -16.542 1.00 32.52 ? 602 THR A OG1 1 ATOM 4798 C CG2 . THR A 1 602 ? 32.045 96.633 -15.925 1.00 32.36 ? 602 THR A CG2 1 ATOM 4799 N N . LEU A 1 603 ? 31.521 99.564 -19.704 1.00 21.51 ? 603 LEU A N 1 ATOM 4800 C CA . LEU A 1 603 ? 31.080 100.776 -20.368 1.00 23.37 ? 603 LEU A CA 1 ATOM 4801 C C . LEU A 1 603 ? 30.077 100.452 -21.502 1.00 24.72 ? 603 LEU A C 1 ATOM 4802 O O . LEU A 1 603 ? 28.967 100.963 -21.515 1.00 21.67 ? 603 LEU A O 1 ATOM 4803 C CB . LEU A 1 603 ? 32.271 101.560 -20.913 1.00 29.68 ? 603 LEU A CB 1 ATOM 4804 C CG . LEU A 1 603 ? 32.991 102.425 -19.873 1.00 34.37 ? 603 LEU A CG 1 ATOM 4805 C CD1 . LEU A 1 603 ? 31.988 103.442 -19.279 1.00 36.15 ? 603 LEU A CD1 1 ATOM 4806 C CD2 . LEU A 1 603 ? 33.582 101.552 -18.782 1.00 38.99 ? 603 LEU A CD2 1 ATOM 4807 N N . THR A 1 604 ? 30.434 99.575 -22.445 1.00 22.05 ? 604 THR A N 1 ATOM 4808 C CA . THR A 1 604 ? 29.526 99.215 -23.515 1.00 18.56 ? 604 THR A CA 1 ATOM 4809 C C . THR A 1 604 ? 28.539 98.091 -23.100 1.00 13.23 ? 604 THR A C 1 ATOM 4810 O O . THR A 1 604 ? 27.594 97.830 -23.860 1.00 16.63 ? 604 THR A O 1 ATOM 4811 C CB . THR A 1 604 ? 30.300 98.653 -24.757 1.00 20.51 ? 604 THR A CB 1 ATOM 4812 O OG1 . THR A 1 604 ? 31.077 97.508 -24.317 1.00 21.81 ? 604 THR A OG1 1 ATOM 4813 C CG2 . THR A 1 604 ? 31.216 99.739 -25.382 1.00 22.81 ? 604 THR A CG2 1 ATOM 4814 N N . LYS A 1 605 ? 28.812 97.427 -21.973 1.00 15.62 ? 605 LYS A N 1 ATOM 4815 C CA . LYS A 1 605 ? 27.961 96.315 -21.503 1.00 17.95 ? 605 LYS A CA 1 ATOM 4816 C C . LYS A 1 605 ? 27.960 95.175 -22.514 1.00 19.68 ? 605 LYS A C 1 ATOM 4817 O O . LYS A 1 605 ? 26.915 94.635 -22.892 1.00 21.66 ? 605 LYS A O 1 ATOM 4818 C CB . LYS A 1 605 ? 26.525 96.782 -21.296 1.00 19.55 ? 605 LYS A CB 1 ATOM 4819 C CG . LYS A 1 605 ? 26.428 97.984 -20.369 1.00 20.29 ? 605 LYS A CG 1 ATOM 4820 C CD . LYS A 1 605 ? 26.745 97.593 -18.941 1.00 20.01 ? 605 LYS A CD 1 ATOM 4821 C CE . LYS A 1 605 ? 26.760 98.847 -18.034 1.00 21.22 ? 605 LYS A CE 1 ATOM 4822 N NZ . LYS A 1 605 ? 26.926 98.395 -16.635 1.00 29.21 ? 605 LYS A NZ 1 ATOM 4823 N N . THR A 1 606 ? 29.142 94.889 -23.029 1.00 15.57 ? 606 THR A N 1 ATOM 4824 C CA . THR A 1 606 ? 29.308 93.745 -23.939 1.00 16.40 ? 606 THR A CA 1 ATOM 4825 C C . THR A 1 606 ? 30.537 92.998 -23.475 1.00 14.61 ? 606 THR A C 1 ATOM 4826 O O . THR A 1 606 ? 31.342 93.487 -22.687 1.00 16.79 ? 606 THR A O 1 ATOM 4827 C CB . THR A 1 606 ? 29.554 94.191 -25.378 1.00 20.36 ? 606 THR A CB 1 ATOM 4828 O OG1 . THR A 1 606 ? 30.725 95.030 -25.399 1.00 22.50 ? 606 THR A OG1 1 ATOM 4829 C CG2 . THR A 1 606 ? 28.271 94.872 -25.975 1.00 21.54 ? 606 THR A CG2 1 ATOM 4830 N N . ILE A 1 607 ? 30.618 91.724 -23.894 1.00 14.83 ? 607 ILE A N 1 ATOM 4831 C CA . ILE A 1 607 ? 31.750 90.854 -23.598 1.00 12.73 ? 607 ILE A CA 1 ATOM 4832 C C . ILE A 1 607 ? 32.433 90.670 -24.956 1.00 11.92 ? 607 ILE A C 1 ATOM 4833 O O . ILE A 1 607 ? 31.836 90.092 -25.891 1.00 12.08 ? 607 ILE A O 1 ATOM 4834 C CB . ILE A 1 607 ? 31.245 89.540 -23.080 1.00 12.33 ? 607 ILE A CB 1 ATOM 4835 C CG1 . ILE A 1 607 ? 30.402 89.797 -21.823 1.00 16.19 ? 607 ILE A CG1 1 ATOM 4836 C CG2 . ILE A 1 607 ? 32.449 88.620 -22.769 1.00 14.77 ? 607 ILE A CG2 1 ATOM 4837 C CD1 . ILE A 1 607 ? 29.613 88.593 -21.401 1.00 17.93 ? 607 ILE A CD1 1 ATOM 4838 N N . HIS A 1 608 ? 33.641 91.176 -25.122 1.00 12.63 ? 608 HIS A N 1 ATOM 4839 C CA . HIS A 1 608 ? 34.238 91.171 -26.444 1.00 12.99 ? 608 HIS A CA 1 ATOM 4840 C C . HIS A 1 608 ? 35.754 91.016 -26.311 1.00 11.95 ? 608 HIS A C 1 ATOM 4841 O O . HIS A 1 608 ? 36.316 91.289 -25.275 1.00 15.49 ? 608 HIS A O 1 ATOM 4842 C CB . HIS A 1 608 ? 33.904 92.451 -27.197 1.00 15.75 ? 608 HIS A CB 1 ATOM 4843 C CG . HIS A 1 608 ? 34.390 93.681 -26.521 1.00 17.54 ? 608 HIS A CG 1 ATOM 4844 N ND1 . HIS A 1 608 ? 35.567 94.304 -26.870 1.00 22.23 ? 608 HIS A ND1 1 ATOM 4845 C CD2 . HIS A 1 608 ? 33.852 94.422 -25.531 1.00 21.38 ? 608 HIS A CD2 1 ATOM 4846 C CE1 . HIS A 1 608 ? 35.728 95.380 -26.123 1.00 22.68 ? 608 HIS A CE1 1 ATOM 4847 N NE2 . HIS A 1 608 ? 34.702 95.472 -25.299 1.00 26.37 ? 608 HIS A NE2 1 ATOM 4848 N N . PRO A 1 609 ? 36.400 90.542 -27.358 1.00 11.73 ? 609 PRO A N 1 ATOM 4849 C CA . PRO A 1 609 ? 37.829 90.299 -27.321 1.00 12.37 ? 609 PRO A CA 1 ATOM 4850 C C . PRO A 1 609 ? 38.719 91.401 -27.778 1.00 14.85 ? 609 PRO A C 1 ATOM 4851 O O . PRO A 1 609 ? 38.377 92.153 -28.699 1.00 18.80 ? 609 PRO A O 1 ATOM 4852 C CB . PRO A 1 609 ? 37.974 89.089 -28.243 1.00 13.68 ? 609 PRO A CB 1 ATOM 4853 C CG . PRO A 1 609 ? 36.982 89.356 -29.309 1.00 16.27 ? 609 PRO A CG 1 ATOM 4854 C CD . PRO A 1 609 ? 35.814 90.035 -28.631 1.00 12.33 ? 609 PRO A CD 1 ATOM 4855 N N . GLN A 1 610 ? 39.873 91.452 -27.150 1.00 12.63 ? 610 GLN A N 1 ATOM 4856 C CA . GLN A 1 610 ? 40.874 92.431 -27.531 1.00 15.06 ? 610 GLN A CA 1 ATOM 4857 C C . GLN A 1 610 ? 42.115 91.670 -27.967 1.00 11.43 ? 610 GLN A C 1 ATOM 4858 O O . GLN A 1 610 ? 42.446 90.685 -27.290 1.00 13.13 ? 610 GLN A O 1 ATOM 4859 C CB . GLN A 1 610 ? 41.238 93.322 -26.353 1.00 17.97 ? 610 GLN A CB 1 ATOM 4860 C CG . GLN A 1 610 ? 40.046 93.966 -25.737 1.00 32.63 ? 610 GLN A CG 1 ATOM 4861 C CD . GLN A 1 610 ? 39.626 95.214 -26.472 1.00 37.58 ? 610 GLN A CD 1 ATOM 4862 O OE1 . GLN A 1 610 ? 39.383 95.193 -27.690 1.00 41.32 ? 610 GLN A OE1 1 ATOM 4863 N NE2 . GLN A 1 610 ? 39.533 96.325 -25.733 1.00 41.45 ? 610 GLN A NE2 1 ATOM 4864 N N . GLY A 1 611 ? 42.771 92.108 -29.027 1.00 12.16 ? 611 GLY A N 1 ATOM 4865 C CA . GLY A 1 611 ? 43.983 91.414 -29.450 1.00 13.79 ? 611 GLY A CA 1 ATOM 4866 C C . GLY A 1 611 ? 45.245 92.169 -29.033 1.00 13.91 ? 611 GLY A C 1 ATOM 4867 O O . GLY A 1 611 ? 45.285 93.397 -28.908 1.00 17.11 ? 611 GLY A O 1 ATOM 4868 N N . SER A 1 612 ? 46.319 91.438 -28.807 1.00 14.58 ? 612 SER A N 1 ATOM 4869 C CA . SER A 1 612 ? 47.592 92.075 -28.467 1.00 12.66 ? 612 SER A CA 1 ATOM 4870 C C . SER A 1 612 ? 48.274 92.523 -29.718 1.00 11.08 ? 612 SER A C 1 ATOM 4871 O O . SER A 1 612 ? 48.179 91.931 -30.771 1.00 15.94 ? 612 SER A O 1 ATOM 4872 C CB . SER A 1 612 ? 48.431 91.014 -27.765 1.00 13.63 ? 612 SER A CB 1 ATOM 4873 O OG . SER A 1 612 ? 49.716 91.578 -27.445 1.00 15.58 ? 612 SER A OG 1 ATOM 4874 N N . THR A 1 613 ? 48.995 93.688 -29.631 1.00 18.20 ? 613 THR A N 1 ATOM 4875 C CA . THR A 1 613 ? 49.724 94.191 -30.799 1.00 18.82 ? 613 THR A CA 1 ATOM 4876 C C . THR A 1 613 ? 51.238 93.979 -30.620 1.00 22.11 ? 613 THR A C 1 ATOM 4877 O O . THR A 1 613 ? 52.042 94.473 -31.428 1.00 21.05 ? 613 THR A O 1 ATOM 4878 C CB . THR A 1 613 ? 49.506 95.684 -31.001 1.00 20.52 ? 613 THR A CB 1 ATOM 4879 O OG1 . THR A 1 613 ? 49.982 96.341 -29.810 1.00 18.07 ? 613 THR A OG1 1 ATOM 4880 C CG2 . THR A 1 613 ? 47.991 96.006 -31.107 1.00 22.16 ? 613 THR A CG2 1 ATOM 4881 N N . THR A 1 614 ? 51.607 93.248 -29.565 1.00 18.39 ? 614 THR A N 1 ATOM 4882 C CA . THR A 1 614 ? 53.009 92.901 -29.258 1.00 20.30 ? 614 THR A CA 1 ATOM 4883 C C . THR A 1 614 ? 53.318 91.463 -28.786 1.00 22.21 ? 614 THR A C 1 ATOM 4884 O O . THR A 1 614 ? 54.483 91.128 -28.677 1.00 23.72 ? 614 THR A O 1 ATOM 4885 C CB . THR A 1 614 ? 53.590 93.785 -28.170 1.00 18.90 ? 614 THR A CB 1 ATOM 4886 O OG1 . THR A 1 614 ? 52.832 93.612 -26.979 1.00 18.99 ? 614 THR A OG1 1 ATOM 4887 C CG2 . THR A 1 614 ? 53.618 95.252 -28.592 1.00 19.59 ? 614 THR A CG2 1 ATOM 4888 N N . LYS A 1 615 ? 52.305 90.668 -28.442 1.00 17.44 ? 615 LYS A N 1 ATOM 4889 C CA . LYS A 1 615 ? 52.437 89.240 -28.072 1.00 15.05 ? 615 LYS A CA 1 ATOM 4890 C C . LYS A 1 615 ? 51.686 88.452 -29.143 1.00 14.47 ? 615 LYS A C 1 ATOM 4891 O O . LYS A 1 615 ? 50.626 88.860 -29.561 1.00 14.70 ? 615 LYS A O 1 ATOM 4892 C CB . LYS A 1 615 ? 51.661 88.910 -26.775 1.00 21.37 ? 615 LYS A CB 1 ATOM 4893 C CG . LYS A 1 615 ? 52.153 89.443 -25.436 1.00 29.57 ? 615 LYS A CG 1 ATOM 4894 C CD . LYS A 1 615 ? 52.075 88.364 -24.322 1.00 29.96 ? 615 LYS A CD 1 ATOM 4895 C CE . LYS A 1 615 ? 50.691 87.986 -23.816 1.00 24.21 ? 615 LYS A CE 1 ATOM 4896 N NZ . LYS A 1 615 ? 50.653 87.844 -22.318 1.00 24.75 ? 615 LYS A NZ 1 ATOM 4897 N N . TYR A 1 616 ? 52.207 87.294 -29.531 1.00 11.74 ? 616 TYR A N 1 ATOM 4898 C CA . TYR A 1 616 ? 51.570 86.416 -30.495 1.00 12.32 ? 616 TYR A CA 1 ATOM 4899 C C . TYR A 1 616 ? 51.688 84.978 -30.017 1.00 9.76 ? 616 TYR A C 1 ATOM 4900 O O . TYR A 1 616 ? 52.532 84.685 -29.191 1.00 11.91 ? 616 TYR A O 1 ATOM 4901 C CB . TYR A 1 616 ? 52.243 86.599 -31.855 1.00 12.01 ? 616 TYR A CB 1 ATOM 4902 C CG . TYR A 1 616 ? 52.193 88.047 -32.260 1.00 15.88 ? 616 TYR A CG 1 ATOM 4903 C CD1 . TYR A 1 616 ? 51.046 88.557 -32.843 1.00 14.80 ? 616 TYR A CD1 1 ATOM 4904 C CD2 . TYR A 1 616 ? 53.229 88.909 -31.972 1.00 16.04 ? 616 TYR A CD2 1 ATOM 4905 C CE1 . TYR A 1 616 ? 50.949 89.861 -33.175 1.00 21.28 ? 616 TYR A CE1 1 ATOM 4906 C CE2 . TYR A 1 616 ? 53.138 90.253 -32.306 1.00 19.47 ? 616 TYR A CE2 1 ATOM 4907 C CZ . TYR A 1 616 ? 51.974 90.712 -32.899 1.00 17.95 ? 616 TYR A CZ 1 ATOM 4908 O OH . TYR A 1 616 ? 51.801 92.027 -33.259 1.00 20.37 ? 616 TYR A OH 1 ATOM 4909 N N . ARG A 1 617 ? 50.839 84.098 -30.533 1.00 10.49 ? 617 ARG A N 1 ATOM 4910 C CA . ARG A 1 617 ? 50.952 82.663 -30.203 1.00 9.98 ? 617 ARG A CA 1 ATOM 4911 C C . ARG A 1 617 ? 51.577 81.918 -31.348 1.00 11.32 ? 617 ARG A C 1 ATOM 4912 O O . ARG A 1 617 ? 51.094 82.040 -32.486 1.00 12.32 ? 617 ARG A O 1 ATOM 4913 C CB . ARG A 1 617 ? 49.577 82.038 -29.982 1.00 13.54 ? 617 ARG A CB 1 ATOM 4914 C CG . ARG A 1 617 ? 48.899 82.423 -28.718 1.00 18.17 ? 617 ARG A CG 1 ATOM 4915 C CD . ARG A 1 617 ? 47.496 81.740 -28.645 1.00 17.38 ? 617 ARG A CD 1 ATOM 4916 N NE . ARG A 1 617 ? 47.486 80.273 -28.639 1.00 16.78 ? 617 ARG A NE 1 ATOM 4917 C CZ . ARG A 1 617 ? 46.786 79.525 -29.497 1.00 20.30 ? 617 ARG A CZ 1 ATOM 4918 N NH1 . ARG A 1 617 ? 46.013 80.084 -30.452 1.00 17.17 ? 617 ARG A NH1 1 ATOM 4919 N NH2 . ARG A 1 617 ? 46.862 78.214 -29.432 1.00 16.63 ? 617 ARG A NH2 1 ATOM 4920 N N . ILE A 1 618 ? 52.615 81.124 -31.102 1.00 9.92 ? 618 ILE A N 1 ATOM 4921 C CA . ILE A 1 618 ? 53.171 80.268 -32.151 1.00 10.48 ? 618 ILE A CA 1 ATOM 4922 C C . ILE A 1 618 ? 52.775 78.819 -31.756 1.00 9.38 ? 618 ILE A C 1 ATOM 4923 O O . ILE A 1 618 ? 52.924 78.434 -30.563 1.00 10.63 ? 618 ILE A O 1 ATOM 4924 C CB . ILE A 1 618 ? 54.644 80.449 -32.373 1.00 11.57 ? 618 ILE A CB 1 ATOM 4925 C CG1 . ILE A 1 618 ? 55.017 79.537 -33.547 1.00 15.44 ? 618 ILE A CG1 1 ATOM 4926 C CG2 . ILE A 1 618 ? 55.428 80.186 -31.156 1.00 13.81 ? 618 ILE A CG2 1 ATOM 4927 C CD1 . ILE A 1 618 ? 56.168 79.987 -34.346 1.00 15.44 ? 618 ILE A CD1 1 ATOM 4928 N N . ILE A 1 619 ? 52.313 78.046 -32.708 1.00 9.15 ? 619 ILE A N 1 ATOM 4929 C CA . ILE A 1 619 ? 51.766 76.706 -32.492 1.00 8.58 ? 619 ILE A CA 1 ATOM 4930 C C . ILE A 1 619 ? 52.472 75.756 -33.433 1.00 7.98 ? 619 ILE A C 1 ATOM 4931 O O . ILE A 1 619 ? 52.639 76.048 -34.653 1.00 9.62 ? 619 ILE A O 1 ATOM 4932 C CB . ILE A 1 619 ? 50.249 76.712 -32.881 1.00 11.80 ? 619 ILE A CB 1 ATOM 4933 C CG1 . ILE A 1 619 ? 49.529 77.772 -32.036 1.00 13.44 ? 619 ILE A CG1 1 ATOM 4934 C CG2 . ILE A 1 619 ? 49.604 75.316 -32.800 1.00 12.82 ? 619 ILE A CG2 1 ATOM 4935 C CD1 . ILE A 1 619 ? 48.258 78.346 -32.822 1.00 14.31 ? 619 ILE A CD1 1 ATOM 4936 N N . PHE A 1 620 ? 52.897 74.578 -32.967 1.00 8.24 ? 620 PHE A N 1 ATOM 4937 C CA . PHE A 1 620 ? 53.494 73.603 -33.859 1.00 7.91 ? 620 PHE A CA 1 ATOM 4938 C C . PHE A 1 620 ? 53.297 72.225 -33.254 1.00 7.68 ? 620 PHE A C 1 ATOM 4939 O O . PHE A 1 620 ? 53.001 72.118 -32.034 1.00 8.52 ? 620 PHE A O 1 ATOM 4940 C CB . PHE A 1 620 ? 54.990 73.836 -34.088 1.00 8.78 ? 620 PHE A CB 1 ATOM 4941 C CG . PHE A 1 620 ? 55.833 73.770 -32.819 1.00 7.38 ? 620 PHE A CG 1 ATOM 4942 C CD1 . PHE A 1 620 ? 56.019 74.880 -32.015 1.00 8.04 ? 620 PHE A CD1 1 ATOM 4943 C CD2 . PHE A 1 620 ? 56.494 72.580 -32.489 1.00 9.75 ? 620 PHE A CD2 1 ATOM 4944 C CE1 . PHE A 1 620 ? 56.873 74.829 -30.900 1.00 9.11 ? 620 PHE A CE1 1 ATOM 4945 C CE2 . PHE A 1 620 ? 57.348 72.511 -31.363 1.00 9.04 ? 620 PHE A CE2 1 ATOM 4946 C CZ . PHE A 1 620 ? 57.539 73.634 -30.589 1.00 9.31 ? 620 PHE A CZ 1 ATOM 4947 N N . LYS A 1 621 ? 53.473 71.195 -34.053 1.00 8.17 ? 621 LYS A N 1 ATOM 4948 C CA . LYS A 1 621 ? 53.331 69.826 -33.575 1.00 9.50 ? 621 LYS A CA 1 ATOM 4949 C C . LYS A 1 621 ? 54.621 69.306 -32.989 1.00 10.07 ? 621 LYS A C 1 ATOM 4950 O O . LYS A 1 621 ? 55.667 69.255 -33.657 1.00 11.27 ? 621 LYS A O 1 ATOM 4951 C CB . LYS A 1 621 ? 52.908 68.960 -34.764 1.00 10.07 ? 621 LYS A CB 1 ATOM 4952 C CG . LYS A 1 621 ? 52.584 67.507 -34.351 1.00 12.51 ? 621 LYS A CG 1 ATOM 4953 C CD . LYS A 1 621 ? 51.778 66.790 -35.492 1.00 16.32 ? 621 LYS A CD 1 ATOM 4954 C CE . LYS A 1 621 ? 52.468 66.840 -36.790 1.00 20.85 ? 621 LYS A CE 1 ATOM 4955 N NZ . LYS A 1 621 ? 51.638 66.126 -37.872 1.00 25.70 ? 621 LYS A NZ 1 ATOM 4956 N N . ALA A 1 622 ? 54.589 69.019 -31.696 1.00 9.35 ? 622 ALA A N 1 ATOM 4957 C CA . ALA A 1 622 ? 55.760 68.389 -31.045 1.00 8.49 ? 622 ALA A CA 1 ATOM 4958 C C . ALA A 1 622 ? 55.637 66.862 -31.090 1.00 9.18 ? 622 ALA A C 1 ATOM 4959 O O . ALA A 1 622 ? 54.519 66.339 -30.960 1.00 11.20 ? 622 ALA A O 1 ATOM 4960 C CB . ALA A 1 622 ? 55.875 68.810 -29.571 1.00 8.59 ? 622 ALA A CB 1 ATOM 4961 N N . ARG A 1 623 ? 56.747 66.179 -31.310 1.00 8.04 ? 623 ARG A N 1 ATOM 4962 C CA . ARG A 1 623 ? 56.739 64.684 -31.336 1.00 8.55 ? 623 ARG A CA 1 ATOM 4963 C C . ARG A 1 623 ? 57.762 64.282 -30.299 1.00 7.54 ? 623 ARG A C 1 ATOM 4964 O O . ARG A 1 623 ? 58.930 64.659 -30.375 1.00 9.31 ? 623 ARG A O 1 ATOM 4965 C CB . ARG A 1 623 ? 57.117 64.188 -32.747 1.00 9.76 ? 623 ARG A CB 1 ATOM 4966 C CG . ARG A 1 623 ? 57.145 62.663 -32.759 1.00 11.97 ? 623 ARG A CG 1 ATOM 4967 C CD . ARG A 1 623 ? 57.068 62.054 -34.233 1.00 15.98 ? 623 ARG A CD 1 ATOM 4968 N NE . ARG A 1 623 ? 57.151 60.567 -34.220 1.00 16.36 ? 623 ARG A NE 1 ATOM 4969 C CZ . ARG A 1 623 ? 58.314 59.946 -34.173 1.00 19.96 ? 623 ARG A CZ 1 ATOM 4970 N NH1 . ARG A 1 623 ? 59.458 60.616 -34.158 1.00 21.54 ? 623 ARG A NH1 1 ATOM 4971 N NH2 . ARG A 1 623 ? 58.335 58.639 -34.045 1.00 20.04 ? 623 ARG A NH2 1 ATOM 4972 N N . VAL A 1 624 ? 57.273 63.511 -29.307 1.00 7.13 ? 624 VAL A N 1 ATOM 4973 C CA . VAL A 1 624 ? 58.095 63.221 -28.116 1.00 7.56 ? 624 VAL A CA 1 ATOM 4974 C C . VAL A 1 624 ? 58.138 61.739 -27.847 1.00 6.10 ? 624 VAL A C 1 ATOM 4975 O O . VAL A 1 624 ? 57.116 61.057 -27.902 1.00 7.54 ? 624 VAL A O 1 ATOM 4976 C CB . VAL A 1 624 ? 57.479 64.017 -26.907 1.00 7.56 ? 624 VAL A CB 1 ATOM 4977 C CG1 . VAL A 1 624 ? 58.465 63.966 -25.726 1.00 8.71 ? 624 VAL A CG1 1 ATOM 4978 C CG2 . VAL A 1 624 ? 57.130 65.519 -27.324 1.00 8.55 ? 624 VAL A CG2 1 ATOM 4979 N N . PRO A 1 625 ? 59.347 61.254 -27.439 1.00 6.33 ? 625 PRO A N 1 ATOM 4980 C CA . PRO A 1 625 ? 59.466 59.808 -27.180 1.00 7.00 ? 625 PRO A CA 1 ATOM 4981 C C . PRO A 1 625 ? 58.643 59.351 -25.965 1.00 7.20 ? 625 PRO A C 1 ATOM 4982 O O . PRO A 1 625 ? 58.215 60.158 -25.133 1.00 7.21 ? 625 PRO A O 1 ATOM 4983 C CB . PRO A 1 625 ? 60.945 59.624 -26.812 1.00 8.70 ? 625 PRO A CB 1 ATOM 4984 C CG . PRO A 1 625 ? 61.689 60.818 -27.488 1.00 9.27 ? 625 PRO A CG 1 ATOM 4985 C CD . PRO A 1 625 ? 60.656 61.936 -27.337 1.00 8.28 ? 625 PRO A CD 1 ATOM 4986 N N . PRO A 1 626 ? 58.437 58.054 -25.828 1.00 7.23 ? 626 PRO A N 1 ATOM 4987 C CA . PRO A 1 626 ? 57.716 57.505 -24.655 1.00 6.75 ? 626 PRO A CA 1 ATOM 4988 C C . PRO A 1 626 ? 58.524 57.930 -23.395 1.00 6.39 ? 626 PRO A C 1 ATOM 4989 O O . PRO A 1 626 ? 59.742 57.763 -23.327 1.00 6.72 ? 626 PRO A O 1 ATOM 4990 C CB . PRO A 1 626 ? 57.883 55.988 -24.819 1.00 7.82 ? 626 PRO A CB 1 ATOM 4991 C CG . PRO A 1 626 ? 58.169 55.797 -26.343 1.00 7.23 ? 626 PRO A CG 1 ATOM 4992 C CD . PRO A 1 626 ? 59.035 56.984 -26.675 1.00 8.30 ? 626 PRO A CD 1 ATOM 4993 N N . MET A 1 627 ? 57.813 58.474 -22.391 1.00 5.60 ? 627 MET A N 1 ATOM 4994 C CA . MET A 1 627 ? 58.437 58.893 -21.102 1.00 5.66 ? 627 MET A CA 1 ATOM 4995 C C . MET A 1 627 ? 59.707 59.667 -21.374 1.00 6.46 ? 627 MET A C 1 ATOM 4996 O O . MET A 1 627 ? 60.745 59.506 -20.701 1.00 7.60 ? 627 MET A O 1 ATOM 4997 C CB . MET A 1 627 ? 58.757 57.649 -20.249 1.00 7.44 ? 627 MET A CB 1 ATOM 4998 C CG . MET A 1 627 ? 57.468 56.901 -19.885 1.00 7.16 ? 627 MET A CG 1 ATOM 4999 S SD . MET A 1 627 ? 57.649 55.270 -19.166 1.00 9.85 ? 627 MET A SD 1 ATOM 5000 C CE . MET A 1 627 ? 58.482 55.552 -17.677 1.00 9.91 ? 627 MET A CE 1 ATOM 5001 N N . GLY A 1 628 ? 59.610 60.578 -22.359 1.00 6.99 ? 628 GLY A N 1 ATOM 5002 C CA . GLY A 1 628 ? 60.812 61.251 -22.869 1.00 7.35 ? 628 GLY A CA 1 ATOM 5003 C C . GLY A 1 628 ? 60.711 62.741 -23.082 1.00 6.00 ? 628 GLY A C 1 ATOM 5004 O O . GLY A 1 628 ? 59.724 63.381 -22.669 1.00 6.85 ? 628 GLY A O 1 ATOM 5005 N N . LEU A 1 629 ? 61.751 63.289 -23.716 1.00 6.60 ? 629 LEU A N 1 ATOM 5006 C CA . LEU A 1 629 ? 61.863 64.760 -23.936 1.00 6.32 ? 629 LEU A CA 1 ATOM 5007 C C . LEU A 1 629 ? 62.278 65.031 -25.355 1.00 7.07 ? 629 LEU A C 1 ATOM 5008 O O . LEU A 1 629 ? 63.037 64.238 -25.969 1.00 7.32 ? 629 LEU A O 1 ATOM 5009 C CB . LEU A 1 629 ? 62.964 65.330 -23.022 1.00 6.64 ? 629 LEU A CB 1 ATOM 5010 C CG . LEU A 1 629 ? 62.725 65.173 -21.516 1.00 7.13 ? 629 LEU A CG 1 ATOM 5011 C CD1 . LEU A 1 629 ? 64.008 65.392 -20.699 1.00 8.59 ? 629 LEU A CD1 1 ATOM 5012 C CD2 . LEU A 1 629 ? 61.670 66.194 -21.086 1.00 7.89 ? 629 LEU A CD2 1 ATOM 5013 N N . ALA A 1 630 ? 61.842 66.164 -25.874 1.00 6.80 ? 630 ALA A N 1 ATOM 5014 C CA . ALA A 1 630 ? 62.238 66.596 -27.249 1.00 7.01 ? 630 ALA A CA 1 ATOM 5015 C C . ALA A 1 630 ? 62.453 68.100 -27.218 1.00 6.72 ? 630 ALA A C 1 ATOM 5016 O O . ALA A 1 630 ? 61.632 68.867 -26.671 1.00 7.89 ? 630 ALA A O 1 ATOM 5017 C CB . ALA A 1 630 ? 61.131 66.236 -28.252 1.00 9.47 ? 630 ALA A CB 1 ATOM 5018 N N . THR A 1 631 ? 63.551 68.542 -27.828 1.00 7.71 ? 631 THR A N 1 ATOM 5019 C CA . THR A 1 631 ? 63.955 69.955 -27.836 1.00 7.03 ? 631 THR A CA 1 ATOM 5020 C C . THR A 1 631 ? 63.675 70.601 -29.189 1.00 7.23 ? 631 THR A C 1 ATOM 5021 O O . THR A 1 631 ? 63.935 69.999 -30.224 1.00 8.65 ? 631 THR A O 1 ATOM 5022 C CB . THR A 1 631 ? 65.467 70.077 -27.522 1.00 7.71 ? 631 THR A CB 1 ATOM 5023 O OG1 . THR A 1 631 ? 65.750 69.343 -26.331 1.00 8.31 ? 631 THR A OG1 1 ATOM 5024 C CG2 . THR A 1 631 ? 65.911 71.524 -27.355 1.00 8.51 ? 631 THR A CG2 1 ATOM 5025 N N . TYR A 1 632 ? 63.176 71.831 -29.168 1.00 6.65 ? 632 TYR A N 1 ATOM 5026 C CA . TYR A 1 632 ? 62.948 72.601 -30.407 1.00 6.88 ? 632 TYR A CA 1 ATOM 5027 C C . TYR A 1 632 ? 63.523 73.977 -30.181 1.00 8.19 ? 632 TYR A C 1 ATOM 5028 O O . TYR A 1 632 ? 63.820 74.431 -29.053 1.00 7.95 ? 632 TYR A O 1 ATOM 5029 C CB . TYR A 1 632 ? 61.464 72.712 -30.742 1.00 8.62 ? 632 TYR A CB 1 ATOM 5030 C CG . TYR A 1 632 ? 60.821 71.396 -31.087 1.00 7.73 ? 632 TYR A CG 1 ATOM 5031 C CD1 . TYR A 1 632 ? 60.404 70.476 -30.103 1.00 8.66 ? 632 TYR A CD1 1 ATOM 5032 C CD2 . TYR A 1 632 ? 60.632 71.044 -32.417 1.00 8.90 ? 632 TYR A CD2 1 ATOM 5033 C CE1 . TYR A 1 632 ? 59.842 69.262 -30.463 1.00 9.32 ? 632 TYR A CE1 1 ATOM 5034 C CE2 . TYR A 1 632 ? 60.054 69.813 -32.793 1.00 9.52 ? 632 TYR A CE2 1 ATOM 5035 C CZ . TYR A 1 632 ? 59.671 68.935 -31.801 1.00 8.08 ? 632 TYR A CZ 1 ATOM 5036 O OH . TYR A 1 632 ? 59.125 67.698 -32.156 1.00 12.19 ? 632 TYR A OH 1 ATOM 5037 N N . VAL A 1 633 ? 63.668 74.693 -31.294 1.00 7.96 ? 633 VAL A N 1 ATOM 5038 C CA . VAL A 1 633 ? 64.210 76.046 -31.276 1.00 8.20 ? 633 VAL A CA 1 ATOM 5039 C C . VAL A 1 633 ? 63.259 77.013 -32.021 1.00 7.72 ? 633 VAL A C 1 ATOM 5040 O O . VAL A 1 633 ? 62.765 76.677 -33.118 1.00 8.42 ? 633 VAL A O 1 ATOM 5041 C CB . VAL A 1 633 ? 65.617 76.091 -31.971 1.00 8.56 ? 633 VAL A CB 1 ATOM 5042 C CG1 . VAL A 1 633 ? 66.232 77.511 -31.886 1.00 12.19 ? 633 VAL A CG1 1 ATOM 5043 C CG2 . VAL A 1 633 ? 66.549 75.118 -31.260 1.00 10.44 ? 633 VAL A CG2 1 ATOM 5044 N N . LEU A 1 634 ? 62.995 78.143 -31.401 1.00 8.55 ? 634 LEU A N 1 ATOM 5045 C CA . LEU A 1 634 ? 62.156 79.223 -32.020 1.00 8.86 ? 634 LEU A CA 1 ATOM 5046 C C . LEU A 1 634 ? 63.136 80.349 -32.371 1.00 9.11 ? 634 LEU A C 1 ATOM 5047 O O . LEU A 1 634 ? 63.917 80.808 -31.533 1.00 10.42 ? 634 LEU A O 1 ATOM 5048 C CB . LEU A 1 634 ? 61.138 79.764 -31.002 1.00 9.90 ? 634 LEU A CB 1 ATOM 5049 C CG . LEU A 1 634 ? 60.299 78.750 -30.213 1.00 17.52 ? 634 LEU A CG 1 ATOM 5050 C CD1 . LEU A 1 634 ? 59.154 79.559 -29.523 1.00 17.56 ? 634 LEU A CD1 1 ATOM 5051 C CD2 . LEU A 1 634 ? 59.786 77.616 -31.019 1.00 19.43 ? 634 LEU A CD2 1 ATOM 5052 N N . THR A 1 635 ? 63.098 80.754 -33.670 1.00 9.00 ? 635 THR A N 1 ATOM 5053 C CA . THR A 1 635 ? 64.043 81.792 -34.171 1.00 9.18 ? 635 THR A CA 1 ATOM 5054 C C . THR A 1 635 ? 63.278 82.921 -34.833 1.00 10.34 ? 635 THR A C 1 ATOM 5055 O O . THR A 1 635 ? 62.347 82.689 -35.613 1.00 11.27 ? 635 THR A O 1 ATOM 5056 C CB . THR A 1 635 ? 64.956 81.137 -35.221 1.00 10.46 ? 635 THR A CB 1 ATOM 5057 O OG1 . THR A 1 635 ? 65.636 80.004 -34.615 1.00 11.28 ? 635 THR A OG1 1 ATOM 5058 C CG2 . THR A 1 635 ? 65.990 82.142 -35.733 1.00 11.01 ? 635 THR A CG2 1 ATOM 5059 N N . ILE A 1 636 ? 63.725 84.139 -34.549 1.00 11.03 ? 636 ILE A N 1 ATOM 5060 C CA . ILE A 1 636 ? 63.005 85.283 -35.156 1.00 12.92 ? 636 ILE A CA 1 ATOM 5061 C C . ILE A 1 636 ? 63.630 85.608 -36.517 1.00 13.66 ? 636 ILE A C 1 ATOM 5062 O O . ILE A 1 636 ? 64.775 85.250 -36.793 1.00 13.87 ? 636 ILE A O 1 ATOM 5063 C CB . ILE A 1 636 ? 63.121 86.501 -34.235 1.00 12.27 ? 636 ILE A CB 1 ATOM 5064 C CG1 . ILE A 1 636 ? 62.168 87.639 -34.678 1.00 12.91 ? 636 ILE A CG1 1 ATOM 5065 C CG2 . ILE A 1 636 ? 64.568 86.985 -34.181 1.00 14.19 ? 636 ILE A CG2 1 ATOM 5066 C CD1 . ILE A 1 636 ? 62.123 88.801 -33.653 1.00 16.54 ? 636 ILE A CD1 1 ATOM 5067 N N . SER A 1 637 ? 62.791 86.129 -37.422 1.00 14.18 ? 637 SER A N 1 ATOM 5068 C CA . SER A 1 637 ? 63.307 86.620 -38.730 1.00 16.87 ? 637 SER A CA 1 ATOM 5069 C C . SER A 1 637 ? 62.688 87.990 -38.944 1.00 18.35 ? 637 SER A C 1 ATOM 5070 O O . SER A 1 637 ? 61.840 88.412 -38.202 1.00 16.70 ? 637 SER A O 1 ATOM 5071 C CB . SER A 1 637 ? 62.995 85.694 -39.919 1.00 25.09 ? 637 SER A CB 1 ATOM 5072 O OG . SER A 1 637 ? 61.661 85.290 -39.926 1.00 29.14 ? 637 SER A OG 1 ATOM 5073 N N . ASP A 1 638 ? 63.153 88.700 -39.963 1.00 22.64 ? 638 ASP A N 1 ATOM 5074 C CA . ASP A 1 638 ? 62.613 90.038 -40.171 1.00 27.41 ? 638 ASP A CA 1 ATOM 5075 C C . ASP A 1 638 ? 61.319 90.080 -40.997 1.00 27.46 ? 638 ASP A C 1 ATOM 5076 O O . ASP A 1 638 ? 60.705 91.151 -41.139 1.00 33.42 ? 638 ASP A O 1 ATOM 5077 C CB . ASP A 1 638 ? 63.687 90.916 -40.804 1.00 32.77 ? 638 ASP A CB 1 ATOM 5078 C CG . ASP A 1 638 ? 63.804 90.673 -42.270 1.00 38.99 ? 638 ASP A CG 1 ATOM 5079 O OD1 . ASP A 1 638 ? 63.913 89.479 -42.673 1.00 43.06 ? 638 ASP A OD1 1 ATOM 5080 O OD2 . ASP A 1 638 ? 63.767 91.678 -43.021 1.00 46.36 ? 638 ASP A OD2 1 ATOM 5081 N N . SER A 1 639 ? 60.885 88.933 -41.529 1.00 23.88 ? 639 SER A N 1 ATOM 5082 C CA . SER A 1 639 ? 59.667 88.879 -42.305 1.00 24.31 ? 639 SER A CA 1 ATOM 5083 C C . SER A 1 639 ? 59.104 87.467 -42.243 1.00 24.73 ? 639 SER A C 1 ATOM 5084 O O . SER A 1 639 ? 59.714 86.576 -41.610 1.00 21.34 ? 639 SER A O 1 ATOM 5085 C CB . SER A 1 639 ? 59.954 89.297 -43.759 1.00 24.59 ? 639 SER A CB 1 ATOM 5086 O OG . SER A 1 639 ? 60.970 88.474 -44.302 1.00 30.57 ? 639 SER A OG 1 ATOM 5087 N N . LYS A 1 640 ? 57.965 87.248 -42.882 1.00 21.71 ? 640 LYS A N 1 ATOM 5088 C CA . LYS A 1 640 ? 57.309 85.930 -42.847 1.00 23.60 ? 640 LYS A CA 1 ATOM 5089 C C . LYS A 1 640 ? 58.239 84.772 -43.215 1.00 21.44 ? 640 LYS A C 1 ATOM 5090 O O . LYS A 1 640 ? 58.780 84.704 -44.305 1.00 24.37 ? 640 LYS A O 1 ATOM 5091 C CB . LYS A 1 640 ? 56.073 85.859 -43.772 1.00 23.89 ? 640 LYS A CB 1 ATOM 5092 C CG . LYS A 1 640 ? 54.895 86.786 -43.386 1.00 33.97 ? 640 LYS A CG 1 ATOM 5093 C CD . LYS A 1 640 ? 53.537 86.367 -44.037 1.00 36.11 ? 640 LYS A CD 1 ATOM 5094 C CE . LYS A 1 640 ? 53.489 86.486 -45.549 1.00 40.21 ? 640 LYS A CE 1 ATOM 5095 N NZ . LYS A 1 640 ? 53.587 87.885 -46.080 1.00 40.79 ? 640 LYS A NZ 1 ATOM 5096 N N . PRO A 1 641 ? 58.404 83.806 -42.306 1.00 18.37 ? 641 PRO A N 1 ATOM 5097 C CA . PRO A 1 641 ? 59.245 82.629 -42.487 1.00 19.35 ? 641 PRO A CA 1 ATOM 5098 C C . PRO A 1 641 ? 58.581 81.666 -43.446 1.00 15.60 ? 641 PRO A C 1 ATOM 5099 O O . PRO A 1 641 ? 57.355 81.537 -43.489 1.00 17.78 ? 641 PRO A O 1 ATOM 5100 C CB . PRO A 1 641 ? 59.263 81.983 -41.081 1.00 21.88 ? 641 PRO A CB 1 ATOM 5101 C CG . PRO A 1 641 ? 58.942 83.038 -40.189 1.00 18.87 ? 641 PRO A CG 1 ATOM 5102 C CD . PRO A 1 641 ? 57.980 83.941 -40.900 1.00 18.68 ? 641 PRO A CD 1 ATOM 5103 N N . GLU A 1 642 ? 59.372 80.897 -44.169 1.00 15.67 ? 642 GLU A N 1 ATOM 5104 C CA . GLU A 1 642 ? 58.821 79.947 -45.111 1.00 16.27 ? 642 GLU A CA 1 ATOM 5105 C C . GLU A 1 642 ? 57.881 78.855 -44.570 1.00 17.02 ? 642 GLU A C 1 ATOM 5106 O O . GLU A 1 642 ? 56.943 78.403 -45.222 1.00 20.72 ? 642 GLU A O 1 ATOM 5107 C CB . GLU A 1 642 ? 59.981 79.229 -45.821 1.00 21.26 ? 642 GLU A CB 1 ATOM 5108 C CG . GLU A 1 642 ? 59.570 78.105 -46.736 1.00 24.98 ? 642 GLU A CG 1 ATOM 5109 C CD . GLU A 1 642 ? 60.790 77.480 -47.438 1.00 34.13 ? 642 GLU A CD 1 ATOM 5110 O OE1 . GLU A 1 642 ? 61.860 78.141 -47.504 1.00 35.61 ? 642 GLU A OE1 1 ATOM 5111 O OE2 . GLU A 1 642 ? 60.671 76.324 -47.914 1.00 40.67 ? 642 GLU A OE2 1 ATOM 5112 N N . HIS A 1 643 ? 58.156 78.408 -43.351 1.00 14.17 ? 643 HIS A N 1 ATOM 5113 C CA . HIS A 1 643 ? 57.395 77.303 -42.769 1.00 13.57 ? 643 HIS A CA 1 ATOM 5114 C C . HIS A 1 643 ? 56.422 77.707 -41.664 1.00 13.48 ? 643 HIS A C 1 ATOM 5115 O O . HIS A 1 643 ? 56.005 76.831 -40.907 1.00 13.74 ? 643 HIS A O 1 ATOM 5116 C CB . HIS A 1 643 ? 58.361 76.256 -42.210 1.00 14.00 ? 643 HIS A CB 1 ATOM 5117 C CG . HIS A 1 643 ? 59.242 75.655 -43.253 1.00 16.99 ? 643 HIS A CG 1 ATOM 5118 N ND1 . HIS A 1 643 ? 58.813 74.642 -44.069 1.00 23.23 ? 643 HIS A ND1 1 ATOM 5119 C CD2 . HIS A 1 643 ? 60.482 75.990 -43.670 1.00 18.06 ? 643 HIS A CD2 1 ATOM 5120 C CE1 . HIS A 1 643 ? 59.749 74.382 -44.971 1.00 20.29 ? 643 HIS A CE1 1 ATOM 5121 N NE2 . HIS A 1 643 ? 60.765 75.190 -44.751 1.00 19.51 ? 643 HIS A NE2 1 ATOM 5122 N N . THR A 1 644 ? 56.074 78.978 -41.598 1.00 11.04 ? 644 THR A N 1 ATOM 5123 C CA . THR A 1 644 ? 55.088 79.494 -40.641 1.00 11.08 ? 644 THR A CA 1 ATOM 5124 C C . THR A 1 644 ? 53.934 80.147 -41.380 1.00 13.01 ? 644 THR A C 1 ATOM 5125 O O . THR A 1 644 ? 54.152 80.977 -42.260 1.00 15.11 ? 644 THR A O 1 ATOM 5126 C CB . THR A 1 644 ? 55.740 80.490 -39.695 1.00 12.66 ? 644 THR A CB 1 ATOM 5127 O OG1 . THR A 1 644 ? 56.778 79.823 -38.969 1.00 12.38 ? 644 THR A OG1 1 ATOM 5128 C CG2 . THR A 1 644 ? 54.747 81.042 -38.687 1.00 12.20 ? 644 THR A CG2 1 ATOM 5129 N N . SER A 1 645 ? 52.717 79.729 -41.053 1.00 10.92 ? 645 SER A N 1 ATOM 5130 C CA . SER A 1 645 ? 51.510 80.323 -41.663 1.00 11.05 ? 645 SER A CA 1 ATOM 5131 C C . SER A 1 645 ? 50.821 81.166 -40.618 1.00 10.38 ? 645 SER A C 1 ATOM 5132 O O . SER A 1 645 ? 51.169 81.124 -39.441 1.00 11.58 ? 645 SER A O 1 ATOM 5133 C CB . SER A 1 645 ? 50.541 79.285 -42.171 1.00 12.70 ? 645 SER A CB 1 ATOM 5134 O OG . SER A 1 645 ? 50.066 78.521 -41.046 1.00 13.25 ? 645 SER A OG 1 ATOM 5135 N N . TYR A 1 646 ? 49.873 81.986 -41.058 1.00 10.02 ? 646 TYR A N 1 ATOM 5136 C CA . TYR A 1 646 ? 49.185 82.926 -40.173 1.00 9.84 ? 646 TYR A CA 1 ATOM 5137 C C . TYR A 1 646 ? 47.678 82.711 -40.229 1.00 11.32 ? 646 TYR A C 1 ATOM 5138 O O . TYR A 1 646 ? 47.116 82.641 -41.300 1.00 14.52 ? 646 TYR A O 1 ATOM 5139 C CB . TYR A 1 646 ? 49.546 84.377 -40.545 1.00 13.52 ? 646 TYR A CB 1 ATOM 5140 C CG . TYR A 1 646 ? 51.019 84.585 -40.309 1.00 12.00 ? 646 TYR A CG 1 ATOM 5141 C CD1 . TYR A 1 646 ? 51.942 84.283 -41.294 1.00 12.97 ? 646 TYR A CD1 1 ATOM 5142 C CD2 . TYR A 1 646 ? 51.488 84.951 -39.072 1.00 11.20 ? 646 TYR A CD2 1 ATOM 5143 C CE1 . TYR A 1 646 ? 53.277 84.397 -41.060 1.00 14.45 ? 646 TYR A CE1 1 ATOM 5144 C CE2 . TYR A 1 646 ? 52.824 85.072 -38.834 1.00 14.09 ? 646 TYR A CE2 1 ATOM 5145 C CZ . TYR A 1 646 ? 53.707 84.795 -39.835 1.00 12.93 ? 646 TYR A CZ 1 ATOM 5146 O OH . TYR A 1 646 ? 55.039 84.905 -39.569 1.00 16.57 ? 646 TYR A OH 1 ATOM 5147 N N . ALA A 1 647 ? 47.030 82.632 -39.072 1.00 9.57 ? 647 ALA A N 1 ATOM 5148 C CA . ALA A 1 647 ? 45.576 82.439 -39.006 1.00 9.89 ? 647 ALA A CA 1 ATOM 5149 C C . ALA A 1 647 ? 44.814 83.664 -39.525 1.00 10.89 ? 647 ALA A C 1 ATOM 5150 O O . ALA A 1 647 ? 45.211 84.782 -39.302 1.00 11.03 ? 647 ALA A O 1 ATOM 5151 C CB . ALA A 1 647 ? 45.148 82.135 -37.569 1.00 11.20 ? 647 ALA A CB 1 ATOM 5152 N N . SER A 1 648 ? 43.709 83.432 -40.212 1.00 10.75 ? 648 SER A N 1 ATOM 5153 C CA . SER A 1 648 ? 42.719 84.492 -40.416 1.00 10.35 ? 648 SER A CA 1 ATOM 5154 C C . SER A 1 648 ? 41.843 84.656 -39.171 1.00 9.20 ? 648 SER A C 1 ATOM 5155 O O . SER A 1 648 ? 41.692 83.724 -38.402 1.00 9.88 ? 648 SER A O 1 ATOM 5156 C CB A SER A 1 648 ? 41.983 84.221 -41.661 0.50 14.79 ? 648 SER A CB 1 ATOM 5157 C CB B SER A 1 648 ? 41.835 83.991 -41.561 0.50 15.90 ? 648 SER A CB 1 ATOM 5158 O OG A SER A 1 648 ? 41.204 83.065 -41.541 0.50 19.06 ? 648 SER A OG 1 ATOM 5159 O OG B SER A 1 648 ? 42.546 83.946 -42.784 0.50 28.03 ? 648 SER A OG 1 ATOM 5160 N N . ASN A 1 649 ? 41.272 85.838 -38.986 1.00 9.90 ? 649 ASN A N 1 ATOM 5161 C CA . ASN A 1 649 ? 40.403 86.117 -37.845 1.00 9.45 ? 649 ASN A CA 1 ATOM 5162 C C . ASN A 1 649 ? 39.188 86.892 -38.286 1.00 9.55 ? 649 ASN A C 1 ATOM 5163 O O . ASN A 1 649 ? 39.297 87.855 -39.030 1.00 10.79 ? 649 ASN A O 1 ATOM 5164 C CB . ASN A 1 649 ? 41.140 86.902 -36.767 1.00 9.51 ? 649 ASN A CB 1 ATOM 5165 C CG . ASN A 1 649 ? 42.320 86.129 -36.194 1.00 11.29 ? 649 ASN A CG 1 ATOM 5166 O OD1 . ASN A 1 649 ? 42.188 85.415 -35.213 1.00 11.56 ? 649 ASN A OD1 1 ATOM 5167 N ND2 . ASN A 1 649 ? 43.458 86.259 -36.826 1.00 11.56 ? 649 ASN A ND2 1 ATOM 5168 N N . LEU A 1 650 ? 38.036 86.449 -37.820 1.00 9.40 ? 650 LEU A N 1 ATOM 5169 C CA . LEU A 1 650 ? 36.739 87.065 -38.204 1.00 9.08 ? 650 LEU A CA 1 ATOM 5170 C C . LEU A 1 650 ? 35.957 87.327 -36.959 1.00 9.47 ? 650 LEU A C 1 ATOM 5171 O O . LEU A 1 650 ? 35.671 86.404 -36.172 1.00 10.43 ? 650 LEU A O 1 ATOM 5172 C CB . LEU A 1 650 ? 36.010 86.107 -39.120 1.00 10.33 ? 650 LEU A CB 1 ATOM 5173 C CG . LEU A 1 650 ? 34.557 86.423 -39.478 1.00 10.55 ? 650 LEU A CG 1 ATOM 5174 C CD1 . LEU A 1 650 ? 34.509 87.758 -40.309 1.00 12.07 ? 650 LEU A CD1 1 ATOM 5175 C CD2 . LEU A 1 650 ? 33.957 85.283 -40.291 1.00 15.20 ? 650 LEU A CD2 1 ATOM 5176 N N . LEU A 1 651 ? 35.587 88.577 -36.719 1.00 11.02 ? 651 LEU A N 1 ATOM 5177 C CA . LEU A 1 651 ? 34.783 88.978 -35.567 1.00 10.51 ? 651 LEU A CA 1 ATOM 5178 C C . LEU A 1 651 ? 33.336 89.190 -36.026 1.00 9.51 ? 651 LEU A C 1 ATOM 5179 O O . LEU A 1 651 ? 33.088 90.073 -36.886 1.00 12.75 ? 651 LEU A O 1 ATOM 5180 C CB . LEU A 1 651 ? 35.384 90.261 -34.994 1.00 13.66 ? 651 LEU A CB 1 ATOM 5181 C CG . LEU A 1 651 ? 34.943 90.716 -33.596 1.00 21.99 ? 651 LEU A CG 1 ATOM 5182 C CD1 . LEU A 1 651 ? 33.582 91.310 -33.649 1.00 27.86 ? 651 LEU A CD1 1 ATOM 5183 C CD2 . LEU A 1 651 ? 35.076 89.551 -32.606 1.00 19.42 ? 651 LEU A CD2 1 ATOM 5184 N N . LEU A 1 652 ? 32.395 88.418 -35.538 1.00 9.76 ? 652 LEU A N 1 ATOM 5185 C CA . LEU A 1 652 ? 31.003 88.496 -35.914 1.00 10.22 ? 652 LEU A CA 1 ATOM 5186 C C . LEU A 1 652 ? 30.216 89.174 -34.821 1.00 12.58 ? 652 LEU A C 1 ATOM 5187 O O . LEU A 1 652 ? 30.105 88.707 -33.667 1.00 12.17 ? 652 LEU A O 1 ATOM 5188 C CB . LEU A 1 652 ? 30.482 87.088 -36.219 1.00 9.78 ? 652 LEU A CB 1 ATOM 5189 C CG . LEU A 1 652 ? 31.199 86.369 -37.330 1.00 10.95 ? 652 LEU A CG 1 ATOM 5190 C CD1 . LEU A 1 652 ? 30.669 84.894 -37.499 1.00 11.60 ? 652 LEU A CD1 1 ATOM 5191 C CD2 . LEU A 1 652 ? 31.067 87.124 -38.682 1.00 12.53 ? 652 LEU A CD2 1 ATOM 5192 N N . ARG A 1 653 ? 29.712 90.349 -35.163 1.00 12.75 ? 653 ARG A N 1 ATOM 5193 C CA . ARG A 1 653 ? 28.939 91.152 -34.239 1.00 14.39 ? 653 ARG A CA 1 ATOM 5194 C C . ARG A 1 653 ? 28.327 92.335 -34.963 1.00 15.16 ? 653 ARG A C 1 ATOM 5195 O O . ARG A 1 653 ? 28.818 92.777 -35.987 1.00 17.00 ? 653 ARG A O 1 ATOM 5196 C CB . ARG A 1 653 ? 29.788 91.635 -33.069 1.00 15.08 ? 653 ARG A CB 1 ATOM 5197 C CG . ARG A 1 653 ? 30.794 92.703 -33.442 1.00 18.23 ? 653 ARG A CG 1 ATOM 5198 C CD . ARG A 1 653 ? 31.423 93.294 -32.200 1.00 33.60 ? 653 ARG A CD 1 ATOM 5199 N NE . ARG A 1 653 ? 30.456 94.084 -31.457 1.00 27.95 ? 653 ARG A NE 1 ATOM 5200 C CZ . ARG A 1 653 ? 30.719 94.695 -30.314 1.00 28.19 ? 653 ARG A CZ 1 ATOM 5201 N NH1 . ARG A 1 653 ? 31.922 94.607 -29.787 1.00 31.10 ? 653 ARG A NH1 1 ATOM 5202 N NH2 . ARG A 1 653 ? 29.781 95.400 -29.706 1.00 31.02 ? 653 ARG A NH2 1 ATOM 5203 N N . LYS A 1 654 ? 27.234 92.823 -34.405 1.00 20.09 ? 654 LYS A N 1 ATOM 5204 C CA . LYS A 1 654 ? 26.701 94.140 -34.756 1.00 23.43 ? 654 LYS A CA 1 ATOM 5205 C C . LYS A 1 654 ? 27.632 95.208 -34.212 1.00 20.85 ? 654 LYS A C 1 ATOM 5206 O O . LYS A 1 654 ? 28.213 95.042 -33.155 1.00 23.11 ? 654 LYS A O 1 ATOM 5207 C CB . LYS A 1 654 ? 25.332 94.352 -34.101 1.00 29.24 ? 654 LYS A CB 1 ATOM 5208 C CG . LYS A 1 654 ? 24.416 93.157 -34.114 1.00 29.56 ? 654 LYS A CG 1 ATOM 5209 C CD . LYS A 1 654 ? 23.962 92.856 -35.505 1.00 35.16 ? 654 LYS A CD 1 ATOM 5210 C CE . LYS A 1 654 ? 24.403 93.915 -36.460 1.00 37.30 ? 654 LYS A CE 1 ATOM 5211 N NZ . LYS A 1 654 ? 23.636 93.849 -37.725 1.00 39.33 ? 654 LYS A NZ 1 ATOM 5212 N N . ASN A 1 655 ? 27.737 96.321 -34.915 1.00 22.15 ? 655 ASN A N 1 ATOM 5213 C CA . ASN A 1 655 ? 28.463 97.444 -34.346 1.00 22.48 ? 655 ASN A CA 1 ATOM 5214 C C . ASN A 1 655 ? 29.924 97.128 -34.074 1.00 20.09 ? 655 ASN A C 1 ATOM 5215 O O . ASN A 1 655 ? 30.377 97.335 -32.974 1.00 22.05 ? 655 ASN A O 1 ATOM 5216 C CB . ASN A 1 655 ? 27.829 97.887 -33.021 1.00 25.51 ? 655 ASN A CB 1 ATOM 5217 C CG . ASN A 1 655 ? 28.271 99.285 -32.586 1.00 31.22 ? 655 ASN A CG 1 ATOM 5218 O OD1 . ASN A 1 655 ? 28.800 100.062 -33.375 1.00 34.25 ? 655 ASN A OD1 1 ATOM 5219 N ND2 . ASN A 1 655 ? 28.017 99.616 -31.329 1.00 26.84 ? 655 ASN A ND2 1 ATOM 5220 N N . PRO A 1 656 ? 30.658 96.621 -35.063 1.00 18.03 ? 656 PRO A N 1 ATOM 5221 C CA . PRO A 1 656 ? 32.058 96.326 -34.755 1.00 16.92 ? 656 PRO A CA 1 ATOM 5222 C C . PRO A 1 656 ? 32.929 97.590 -34.757 1.00 15.78 ? 656 PRO A C 1 ATOM 5223 O O . PRO A 1 656 ? 32.587 98.642 -35.320 1.00 15.23 ? 656 PRO A O 1 ATOM 5224 C CB . PRO A 1 656 ? 32.479 95.434 -35.913 1.00 15.37 ? 656 PRO A CB 1 ATOM 5225 C CG . PRO A 1 656 ? 31.695 96.066 -37.078 1.00 15.98 ? 656 PRO A CG 1 ATOM 5226 C CD . PRO A 1 656 ? 30.312 96.224 -36.448 1.00 18.68 ? 656 PRO A CD 1 ATOM 5227 N N . THR A 1 657 ? 34.069 97.464 -34.102 1.00 14.23 ? 657 THR A N 1 ATOM 5228 C CA . THR A 1 657 ? 35.089 98.501 -34.121 1.00 14.68 ? 657 THR A CA 1 ATOM 5229 C C . THR A 1 657 ? 36.397 97.779 -34.504 1.00 14.38 ? 657 THR A C 1 ATOM 5230 O O . THR A 1 657 ? 36.504 96.531 -34.382 1.00 16.45 ? 657 THR A O 1 ATOM 5231 C CB . THR A 1 657 ? 35.278 99.190 -32.787 1.00 16.11 ? 657 THR A CB 1 ATOM 5232 O OG1 . THR A 1 657 ? 35.395 98.188 -31.755 1.00 20.53 ? 657 THR A OG1 1 ATOM 5233 C CG2 . THR A 1 657 ? 34.063 100.104 -32.474 1.00 19.31 ? 657 THR A CG2 1 ATOM 5234 N N . SER A 1 658 ? 37.391 98.536 -34.937 1.00 13.71 ? 658 SER A N 1 ATOM 5235 C CA . SER A 1 658 ? 38.652 98.000 -35.393 1.00 14.39 ? 658 SER A CA 1 ATOM 5236 C C . SER A 1 658 ? 39.400 97.210 -34.301 1.00 16.77 ? 658 SER A C 1 ATOM 5237 O O . SER A 1 658 ? 39.234 97.436 -33.103 1.00 17.74 ? 658 SER A O 1 ATOM 5238 C CB . SER A 1 658 ? 39.511 99.149 -35.864 1.00 18.52 ? 658 SER A CB 1 ATOM 5239 O OG . SER A 1 658 ? 39.816 99.903 -34.712 1.00 22.27 ? 658 SER A OG 1 ATOM 5240 N N . LEU A 1 659 ? 40.232 96.274 -34.767 1.00 15.18 ? 659 LEU A N 1 ATOM 5241 C CA . LEU A 1 659 ? 41.030 95.404 -33.845 1.00 16.27 ? 659 LEU A CA 1 ATOM 5242 C C . LEU A 1 659 ? 42.432 95.257 -34.467 1.00 17.09 ? 659 LEU A C 1 ATOM 5243 O O . LEU A 1 659 ? 42.740 94.302 -35.184 1.00 18.05 ? 659 LEU A O 1 ATOM 5244 C CB . LEU A 1 659 ? 40.395 94.001 -33.718 1.00 16.85 ? 659 LEU A CB 1 ATOM 5245 C CG . LEU A 1 659 ? 39.031 93.869 -33.044 1.00 18.77 ? 659 LEU A CG 1 ATOM 5246 C CD1 . LEU A 1 659 ? 38.480 92.434 -33.216 1.00 23.31 ? 659 LEU A CD1 1 ATOM 5247 C CD2 . LEU A 1 659 ? 39.131 94.180 -31.605 1.00 21.59 ? 659 LEU A CD2 1 ATOM 5248 N N . PRO A 1 660 ? 43.264 96.263 -34.298 1.00 17.17 ? 660 PRO A N 1 ATOM 5249 C CA . PRO A 1 660 ? 44.633 96.228 -34.845 1.00 17.56 ? 660 PRO A CA 1 ATOM 5250 C C . PRO A 1 660 ? 45.490 95.151 -34.099 1.00 15.99 ? 660 PRO A C 1 ATOM 5251 O O . PRO A 1 660 ? 45.262 94.894 -32.923 1.00 16.99 ? 660 PRO A O 1 ATOM 5252 C CB . PRO A 1 660 ? 45.128 97.664 -34.643 1.00 19.39 ? 660 PRO A CB 1 ATOM 5253 C CG . PRO A 1 660 ? 44.393 98.146 -33.459 1.00 21.01 ? 660 PRO A CG 1 ATOM 5254 C CD . PRO A 1 660 ? 43.008 97.452 -33.472 1.00 21.23 ? 660 PRO A CD 1 ATOM 5255 N N . LEU A 1 661 ? 46.416 94.570 -34.836 1.00 16.58 ? 661 LEU A N 1 ATOM 5256 C CA . LEU A 1 661 ? 47.234 93.493 -34.235 1.00 17.52 ? 661 LEU A CA 1 ATOM 5257 C C . LEU A 1 661 ? 48.741 93.714 -34.469 1.00 22.68 ? 661 LEU A C 1 ATOM 5258 O O . LEU A 1 661 ? 49.503 92.740 -34.574 1.00 18.43 ? 661 LEU A O 1 ATOM 5259 C CB . LEU A 1 661 ? 46.824 92.157 -34.874 1.00 15.76 ? 661 LEU A CB 1 ATOM 5260 C CG . LEU A 1 661 ? 45.373 91.713 -34.629 1.00 13.71 ? 661 LEU A CG 1 ATOM 5261 C CD1 . LEU A 1 661 ? 45.118 90.427 -35.435 1.00 13.86 ? 661 LEU A CD1 1 ATOM 5262 C CD2 . LEU A 1 661 ? 45.169 91.475 -33.122 1.00 13.34 ? 661 LEU A CD2 1 ATOM 5263 N N . GLY A 1 662 ? 49.180 94.975 -34.584 1.00 20.70 ? 662 GLY A N 1 ATOM 5264 C CA . GLY A 1 662 ? 50.621 95.256 -34.821 1.00 17.41 ? 662 GLY A CA 1 ATOM 5265 C C . GLY A 1 662 ? 51.197 94.653 -36.071 1.00 19.05 ? 662 GLY A C 1 ATOM 5266 O O . GLY A 1 662 ? 50.619 94.796 -37.181 1.00 21.73 ? 662 GLY A O 1 ATOM 5267 N N . GLN A 1 663 ? 52.283 93.862 -35.884 1.00 20.67 ? 663 GLN A N 1 ATOM 5268 C CA . GLN A 1 663 ? 52.989 93.248 -36.991 1.00 23.63 ? 663 GLN A CA 1 ATOM 5269 C C . GLN A 1 663 ? 52.310 92.062 -37.603 1.00 14.47 ? 663 GLN A C 1 ATOM 5270 O O . GLN A 1 663 ? 52.675 91.629 -38.713 1.00 20.10 ? 663 GLN A O 1 ATOM 5271 C CB . GLN A 1 663 ? 54.392 92.807 -36.564 1.00 25.41 ? 663 GLN A CB 1 ATOM 5272 C CG . GLN A 1 663 ? 55.018 93.601 -35.393 1.00 33.81 ? 663 GLN A CG 1 ATOM 5273 C CD . GLN A 1 663 ? 56.394 93.039 -34.994 1.00 34.83 ? 663 GLN A CD 1 ATOM 5274 O OE1 . GLN A 1 663 ? 57.254 92.814 -35.873 1.00 27.90 ? 663 GLN A OE1 1 ATOM 5275 N NE2 . GLN A 1 663 ? 56.606 92.804 -33.680 1.00 35.44 ? 663 GLN A NE2 1 ATOM 5276 N N . TYR A 1 664 ? 51.266 91.561 -36.937 1.00 18.68 ? 664 TYR A N 1 ATOM 5277 C CA . TYR A 1 664 ? 50.536 90.396 -37.443 1.00 18.85 ? 664 TYR A CA 1 ATOM 5278 C C . TYR A 1 664 ? 50.187 90.653 -38.890 1.00 13.61 ? 664 TYR A C 1 ATOM 5279 O O . TYR A 1 664 ? 49.519 91.672 -39.202 1.00 20.12 ? 664 TYR A O 1 ATOM 5280 C CB . TYR A 1 664 ? 49.319 90.186 -36.549 1.00 17.63 ? 664 TYR A CB 1 ATOM 5281 C CG . TYR A 1 664 ? 48.675 88.845 -36.744 1.00 14.07 ? 664 TYR A CG 1 ATOM 5282 C CD1 . TYR A 1 664 ? 49.203 87.683 -36.126 1.00 12.58 ? 664 TYR A CD1 1 ATOM 5283 C CD2 . TYR A 1 664 ? 47.575 88.704 -37.592 1.00 13.17 ? 664 TYR A CD2 1 ATOM 5284 C CE1 . TYR A 1 664 ? 48.640 86.460 -36.352 1.00 13.47 ? 664 TYR A CE1 1 ATOM 5285 C CE2 . TYR A 1 664 ? 46.990 87.450 -37.847 1.00 12.78 ? 664 TYR A CE2 1 ATOM 5286 C CZ . TYR A 1 664 ? 47.552 86.318 -37.182 1.00 12.69 ? 664 TYR A CZ 1 ATOM 5287 O OH . TYR A 1 664 ? 46.903 85.117 -37.333 1.00 12.84 ? 664 TYR A OH 1 ATOM 5288 N N . PRO A 1 665 ? 50.411 89.744 -39.803 1.00 19.99 ? 665 PRO A N 1 ATOM 5289 C CA . PRO A 1 665 ? 50.303 90.093 -41.218 1.00 21.09 ? 665 PRO A CA 1 ATOM 5290 C C . PRO A 1 665 ? 48.932 89.958 -41.899 1.00 24.00 ? 665 PRO A C 1 ATOM 5291 O O . PRO A 1 665 ? 48.847 90.324 -43.060 1.00 26.55 ? 665 PRO A O 1 ATOM 5292 C CB . PRO A 1 665 ? 51.318 89.173 -41.880 1.00 20.89 ? 665 PRO A CB 1 ATOM 5293 C CG . PRO A 1 665 ? 51.486 88.068 -40.920 1.00 21.74 ? 665 PRO A CG 1 ATOM 5294 C CD . PRO A 1 665 ? 51.290 88.592 -39.585 1.00 17.08 ? 665 PRO A CD 1 ATOM 5295 N N . GLU A 1 666 ? 47.902 89.441 -41.217 1.00 19.41 ? 666 GLU A N 1 ATOM 5296 C CA . GLU A 1 666 ? 46.545 89.357 -41.782 1.00 17.93 ? 666 GLU A CA 1 ATOM 5297 C C . GLU A 1 666 ? 45.655 90.289 -40.980 1.00 18.59 ? 666 GLU A C 1 ATOM 5298 O O . GLU A 1 666 ? 45.618 90.253 -39.745 1.00 16.93 ? 666 GLU A O 1 ATOM 5299 C CB . GLU A 1 666 ? 45.985 87.943 -41.682 1.00 21.22 ? 666 GLU A CB 1 ATOM 5300 C CG A GLU A 1 666 ? 44.490 87.871 -42.018 0.50 36.03 ? 666 GLU A CG 1 ATOM 5301 C CG B GLU A 1 666 ? 46.641 86.875 -42.481 0.50 32.93 ? 666 GLU A CG 1 ATOM 5302 C CD A GLU A 1 666 ? 44.122 86.835 -43.079 0.50 34.07 ? 666 GLU A CD 1 ATOM 5303 C CD B GLU A 1 666 ? 46.595 87.281 -43.941 0.50 34.00 ? 666 GLU A CD 1 ATOM 5304 O OE1 A GLU A 1 666 ? 44.994 86.037 -43.478 0.50 42.84 ? 666 GLU A OE1 1 ATOM 5305 O OE1 B GLU A 1 666 ? 45.513 87.656 -44.430 0.50 41.45 ? 666 GLU A OE1 1 ATOM 5306 O OE2 A GLU A 1 666 ? 42.956 86.815 -43.512 0.50 31.25 ? 666 GLU A OE2 1 ATOM 5307 O OE2 B GLU A 1 666 ? 47.651 87.211 -44.597 0.50 39.36 ? 666 GLU A OE2 1 ATOM 5308 N N . ASP A 1 667 ? 44.928 91.153 -41.684 1.00 16.75 ? 667 ASP A N 1 ATOM 5309 C CA . ASP A 1 667 ? 43.982 92.057 -41.033 1.00 17.18 ? 667 ASP A CA 1 ATOM 5310 C C . ASP A 1 667 ? 42.717 91.292 -40.544 1.00 9.93 ? 667 ASP A C 1 ATOM 5311 O O . ASP A 1 667 ? 42.196 90.443 -41.222 1.00 13.67 ? 667 ASP A O 1 ATOM 5312 C CB . ASP A 1 667 ? 43.524 93.159 -42.006 1.00 18.77 ? 667 ASP A CB 1 ATOM 5313 C CG . ASP A 1 667 ? 44.648 94.074 -42.458 1.00 27.03 ? 667 ASP A CG 1 ATOM 5314 O OD1 . ASP A 1 667 ? 45.676 94.192 -41.771 1.00 25.63 ? 667 ASP A OD1 1 ATOM 5315 O OD2 . ASP A 1 667 ? 44.455 94.713 -43.501 1.00 28.46 ? 667 ASP A OD2 1 ATOM 5316 N N . VAL A 1 668 ? 42.241 91.661 -39.374 1.00 12.23 ? 668 VAL A N 1 ATOM 5317 C CA . VAL A 1 668 ? 40.987 91.084 -38.828 1.00 13.15 ? 668 VAL A CA 1 ATOM 5318 C C . VAL A 1 668 ? 39.829 91.472 -39.740 1.00 12.90 ? 668 VAL A C 1 ATOM 5319 O O . VAL A 1 668 ? 39.802 92.641 -40.222 1.00 13.70 ? 668 VAL A O 1 ATOM 5320 C CB . VAL A 1 668 ? 40.668 91.551 -37.410 1.00 13.64 ? 668 VAL A CB 1 ATOM 5321 C CG1 . VAL A 1 668 ? 39.348 90.949 -36.903 1.00 14.10 ? 668 VAL A CG1 1 ATOM 5322 C CG2 . VAL A 1 668 ? 41.834 91.143 -36.426 1.00 13.16 ? 668 VAL A CG2 1 ATOM 5323 N N . LYS A 1 669 ? 38.942 90.525 -40.028 1.00 10.77 ? 669 LYS A N 1 ATOM 5324 C CA . LYS A 1 669 ? 37.727 90.776 -40.804 1.00 10.82 ? 669 LYS A CA 1 ATOM 5325 C C . LYS A 1 669 ? 36.505 90.822 -39.896 1.00 11.22 ? 669 LYS A C 1 ATOM 5326 O O . LYS A 1 669 ? 36.525 90.288 -38.787 1.00 11.11 ? 669 LYS A O 1 ATOM 5327 C CB . LYS A 1 669 ? 37.527 89.694 -41.872 1.00 15.01 ? 669 LYS A CB 1 ATOM 5328 C CG . LYS A 1 669 ? 38.735 89.459 -42.770 1.00 26.97 ? 669 LYS A CG 1 ATOM 5329 C CD . LYS A 1 669 ? 38.721 90.311 -44.022 1.00 36.23 ? 669 LYS A CD 1 ATOM 5330 C CE . LYS A 1 669 ? 40.140 90.613 -44.503 1.00 31.09 ? 669 LYS A CE 1 ATOM 5331 N NZ . LYS A 1 669 ? 40.260 92.041 -44.917 1.00 35.66 ? 669 LYS A NZ 1 ATOM 5332 N N . PHE A 1 670 ? 35.443 91.462 -40.379 1.00 11.74 ? 670 PHE A N 1 ATOM 5333 C CA . PHE A 1 670 ? 34.240 91.667 -39.577 1.00 11.34 ? 670 PHE A CA 1 ATOM 5334 C C . PHE A 1 670 ? 33.009 91.255 -40.361 1.00 11.81 ? 670 PHE A C 1 ATOM 5335 O O . PHE A 1 670 ? 33.007 91.184 -41.571 1.00 13.57 ? 670 PHE A O 1 ATOM 5336 C CB . PHE A 1 670 ? 34.091 93.173 -39.131 1.00 13.14 ? 670 PHE A CB 1 ATOM 5337 C CG . PHE A 1 670 ? 35.238 93.651 -38.328 1.00 11.20 ? 670 PHE A CG 1 ATOM 5338 C CD1 . PHE A 1 670 ? 36.390 94.133 -38.993 1.00 14.59 ? 670 PHE A CD1 1 ATOM 5339 C CD2 . PHE A 1 670 ? 35.269 93.541 -36.956 1.00 13.73 ? 670 PHE A CD2 1 ATOM 5340 C CE1 . PHE A 1 670 ? 37.531 94.486 -38.282 1.00 15.36 ? 670 PHE A CE1 1 ATOM 5341 C CE2 . PHE A 1 670 ? 36.421 93.896 -36.240 1.00 16.57 ? 670 PHE A CE2 1 ATOM 5342 C CZ . PHE A 1 670 ? 37.559 94.377 -36.942 1.00 14.53 ? 670 PHE A CZ 1 ATOM 5343 N N . GLY A 1 671 ? 31.933 90.943 -39.632 1.00 12.93 ? 671 GLY A N 1 ATOM 5344 C CA . GLY A 1 671 ? 30.663 90.603 -40.278 1.00 13.41 ? 671 GLY A CA 1 ATOM 5345 C C . GLY A 1 671 ? 29.537 90.540 -39.289 1.00 12.93 ? 671 GLY A C 1 ATOM 5346 O O . GLY A 1 671 ? 29.757 90.512 -38.076 1.00 11.41 ? 671 GLY A O 1 ATOM 5347 N N . ASP A 1 672 ? 28.317 90.564 -39.805 1.00 12.32 ? 672 ASP A N 1 ATOM 5348 C CA . ASP A 1 672 ? 27.170 90.405 -38.927 1.00 13.24 ? 672 ASP A CA 1 ATOM 5349 C C . ASP A 1 672 ? 27.136 88.893 -38.503 1.00 12.54 ? 672 ASP A C 1 ATOM 5350 O O . ASP A 1 672 ? 27.626 88.013 -39.216 1.00 12.68 ? 672 ASP A O 1 ATOM 5351 C CB . ASP A 1 672 ? 25.851 90.646 -39.694 1.00 15.80 ? 672 ASP A CB 1 ATOM 5352 C CG . ASP A 1 672 ? 25.543 92.106 -39.937 1.00 23.82 ? 672 ASP A CG 1 ATOM 5353 O OD1 . ASP A 1 672 ? 26.204 92.988 -39.404 1.00 22.91 ? 672 ASP A OD1 1 ATOM 5354 O OD2 . ASP A 1 672 ? 24.564 92.353 -40.674 1.00 27.23 ? 672 ASP A OD2 1 ATOM 5355 N N . PRO A 1 673 ? 26.536 88.601 -37.329 1.00 12.58 ? 673 PRO A N 1 ATOM 5356 C CA . PRO A 1 673 ? 26.445 87.195 -36.874 1.00 12.63 ? 673 PRO A CA 1 ATOM 5357 C C . PRO A 1 673 ? 25.846 86.340 -37.986 1.00 12.99 ? 673 PRO A C 1 ATOM 5358 O O . PRO A 1 673 ? 24.925 86.779 -38.706 1.00 13.54 ? 673 PRO A O 1 ATOM 5359 C CB . PRO A 1 673 ? 25.501 87.292 -35.692 1.00 14.20 ? 673 PRO A CB 1 ATOM 5360 C CG . PRO A 1 673 ? 25.871 88.621 -35.077 1.00 16.48 ? 673 PRO A CG 1 ATOM 5361 C CD . PRO A 1 673 ? 25.965 89.527 -36.327 1.00 15.18 ? 673 PRO A CD 1 ATOM 5362 N N . ARG A 1 674 ? 26.358 85.130 -38.123 1.00 11.99 ? 674 ARG A N 1 ATOM 5363 C CA . ARG A 1 674 ? 25.888 84.197 -39.159 1.00 12.21 ? 674 ARG A CA 1 ATOM 5364 C C . ARG A 1 674 ? 26.368 82.806 -38.796 1.00 12.46 ? 674 ARG A C 1 ATOM 5365 O O . ARG A 1 674 ? 27.341 82.664 -38.020 1.00 12.66 ? 674 ARG A O 1 ATOM 5366 C CB . ARG A 1 674 ? 26.451 84.577 -40.552 1.00 12.51 ? 674 ARG A CB 1 ATOM 5367 C CG . ARG A 1 674 ? 27.986 84.547 -40.682 1.00 15.81 ? 674 ARG A CG 1 ATOM 5368 C CD . ARG A 1 674 ? 28.373 84.626 -42.178 1.00 18.45 ? 674 ARG A CD 1 ATOM 5369 N NE . ARG A 1 674 ? 29.751 84.298 -42.526 1.00 22.29 ? 674 ARG A NE 1 ATOM 5370 C CZ . ARG A 1 674 ? 30.744 85.181 -42.666 1.00 22.18 ? 674 ARG A CZ 1 ATOM 5371 N NH1 . ARG A 1 674 ? 30.552 86.509 -42.470 1.00 22.64 ? 674 ARG A NH1 1 ATOM 5372 N NH2 . ARG A 1 674 ? 31.945 84.721 -43.055 1.00 24.90 ? 674 ARG A NH2 1 ATOM 5373 N N . GLU A 1 675 ? 25.725 81.793 -39.355 1.00 12.38 ? 675 GLU A N 1 ATOM 5374 C CA . GLU A 1 675 ? 26.174 80.428 -39.181 1.00 11.73 ? 675 GLU A CA 1 ATOM 5375 C C . GLU A 1 675 ? 27.512 80.240 -39.912 1.00 13.35 ? 675 GLU A C 1 ATOM 5376 O O . GLU A 1 675 ? 27.809 80.892 -40.961 1.00 15.85 ? 675 GLU A O 1 ATOM 5377 C CB . GLU A 1 675 ? 25.118 79.459 -39.710 1.00 16.84 ? 675 GLU A CB 1 ATOM 5378 C CG . GLU A 1 675 ? 23.865 79.589 -38.905 1.00 18.46 ? 675 GLU A CG 1 ATOM 5379 C CD . GLU A 1 675 ? 23.013 78.317 -38.849 1.00 26.92 ? 675 GLU A CD 1 ATOM 5380 O OE1 . GLU A 1 675 ? 23.126 77.493 -39.799 1.00 29.85 ? 675 GLU A OE1 1 ATOM 5381 O OE2 . GLU A 1 675 ? 22.242 78.166 -37.852 1.00 30.99 ? 675 GLU A OE2 1 ATOM 5382 N N . ILE A 1 676 ? 28.368 79.402 -39.350 1.00 12.98 ? 676 ILE A N 1 ATOM 5383 C CA . ILE A 1 676 ? 29.657 79.137 -39.965 1.00 13.27 ? 676 ILE A CA 1 ATOM 5384 C C . ILE A 1 676 ? 30.031 77.673 -39.832 1.00 12.80 ? 676 ILE A C 1 ATOM 5385 O O . ILE A 1 676 ? 29.547 76.988 -38.942 1.00 14.65 ? 676 ILE A O 1 ATOM 5386 C CB . ILE A 1 676 ? 30.768 79.980 -39.352 1.00 21.16 ? 676 ILE A CB 1 ATOM 5387 C CG1 . ILE A 1 676 ? 30.866 79.726 -37.863 1.00 18.38 ? 676 ILE A CG1 1 ATOM 5388 C CG2 . ILE A 1 676 ? 30.593 81.473 -39.669 1.00 25.15 ? 676 ILE A CG2 1 ATOM 5389 C CD1 . ILE A 1 676 ? 32.275 79.601 -37.398 1.00 31.26 ? 676 ILE A CD1 1 ATOM 5390 N N . SER A 1 677 ? 30.891 77.215 -40.728 1.00 11.55 ? 677 SER A N 1 ATOM 5391 C CA . SER A 1 677 ? 31.417 75.860 -40.676 1.00 13.30 ? 677 SER A CA 1 ATOM 5392 C C . SER A 1 677 ? 32.937 75.875 -40.821 1.00 14.41 ? 677 SER A C 1 ATOM 5393 O O . SER A 1 677 ? 33.496 76.704 -41.519 1.00 15.86 ? 677 SER A O 1 ATOM 5394 C CB A SER A 1 677 ? 30.461 75.072 -41.581 0.50 16.77 ? 677 SER A CB 1 ATOM 5395 C CB B SER A 1 677 ? 30.867 74.983 -41.816 0.50 17.27 ? 677 SER A CB 1 ATOM 5396 O OG A SER A 1 677 ? 31.108 73.975 -42.181 0.50 30.40 ? 677 SER A OG 1 ATOM 5397 O OG B SER A 1 677 ? 29.500 74.719 -41.598 0.50 30.47 ? 677 SER A OG 1 ATOM 5398 N N . LEU A 1 678 ? 33.590 74.943 -40.143 1.00 11.87 ? 678 LEU A N 1 ATOM 5399 C CA . LEU A 1 678 ? 35.044 74.840 -40.161 1.00 11.28 ? 678 LEU A CA 1 ATOM 5400 C C . LEU A 1 678 ? 35.447 73.380 -40.282 1.00 10.70 ? 678 LEU A C 1 ATOM 5401 O O . LEU A 1 678 ? 34.774 72.495 -39.782 1.00 12.37 ? 678 LEU A O 1 ATOM 5402 C CB . LEU A 1 678 ? 35.644 75.412 -38.877 1.00 13.46 ? 678 LEU A CB 1 ATOM 5403 C CG . LEU A 1 678 ? 35.553 76.922 -38.671 1.00 16.24 ? 678 LEU A CG 1 ATOM 5404 C CD1 . LEU A 1 678 ? 35.855 77.245 -37.215 1.00 17.66 ? 678 LEU A CD1 1 ATOM 5405 C CD2 . LEU A 1 678 ? 36.540 77.599 -39.587 1.00 23.33 ? 678 LEU A CD2 1 ATOM 5406 N N . ARG A 1 679 ? 36.569 73.162 -40.945 1.00 10.59 ? 679 ARG A N 1 ATOM 5407 C CA . ARG A 1 679 ? 37.216 71.859 -40.979 1.00 12.06 ? 679 ARG A CA 1 ATOM 5408 C C . ARG A 1 679 ? 38.721 72.073 -40.886 1.00 15.72 ? 679 ARG A C 1 ATOM 5409 O O . ARG A 1 679 ? 39.286 72.821 -41.667 1.00 16.84 ? 679 ARG A O 1 ATOM 5410 C CB . ARG A 1 679 ? 36.889 71.141 -42.293 1.00 14.65 ? 679 ARG A CB 1 ATOM 5411 C CG . ARG A 1 679 ? 37.472 69.754 -42.392 1.00 17.78 ? 679 ARG A CG 1 ATOM 5412 C CD . ARG A 1 679 ? 37.107 69.092 -43.702 1.00 21.07 ? 679 ARG A CD 1 ATOM 5413 N NE . ARG A 1 679 ? 37.326 67.651 -43.632 1.00 24.93 ? 679 ARG A NE 1 ATOM 5414 C CZ . ARG A 1 679 ? 37.298 66.830 -44.675 1.00 31.06 ? 679 ARG A CZ 1 ATOM 5415 N NH1 . ARG A 1 679 ? 37.054 67.297 -45.886 1.00 34.05 ? 679 ARG A NH1 1 ATOM 5416 N NH2 . ARG A 1 679 ? 37.505 65.534 -44.500 1.00 30.36 ? 679 ARG A NH2 1 ATOM 5417 N N . VAL A 1 680 ? 39.364 71.419 -39.926 1.00 11.76 ? 680 VAL A N 1 ATOM 5418 C CA . VAL A 1 680 ? 40.821 71.357 -39.893 1.00 12.55 ? 680 VAL A CA 1 ATOM 5419 C C . VAL A 1 680 ? 41.346 69.996 -40.345 1.00 14.22 ? 680 VAL A C 1 ATOM 5420 O O . VAL A 1 680 ? 40.861 68.964 -39.920 1.00 15.43 ? 680 VAL A O 1 ATOM 5421 C CB . VAL A 1 680 ? 41.376 71.687 -38.491 1.00 11.48 ? 680 VAL A CB 1 ATOM 5422 C CG1 . VAL A 1 680 ? 42.896 71.485 -38.437 1.00 13.08 ? 680 VAL A CG1 1 ATOM 5423 C CG2 . VAL A 1 680 ? 41.021 73.124 -38.110 1.00 12.06 ? 680 VAL A CG2 1 ATOM 5424 N N . GLY A 1 681 ? 42.341 70.023 -41.221 1.00 15.81 ? 681 GLY A N 1 ATOM 5425 C CA . GLY A 1 681 ? 42.938 68.801 -41.729 1.00 19.97 ? 681 GLY A CA 1 ATOM 5426 C C . GLY A 1 681 ? 41.939 67.897 -42.427 1.00 19.02 ? 681 GLY A C 1 ATOM 5427 O O . GLY A 1 681 ? 41.132 68.358 -43.222 1.00 20.35 ? 681 GLY A O 1 ATOM 5428 N N . ASN A 1 682 ? 42.006 66.606 -42.111 1.00 25.83 ? 682 ASN A N 1 ATOM 5429 C CA . ASN A 1 682 ? 41.102 65.603 -42.666 1.00 26.13 ? 682 ASN A CA 1 ATOM 5430 C C . ASN A 1 682 ? 39.885 65.422 -41.777 1.00 27.66 ? 682 ASN A C 1 ATOM 5431 O O . ASN A 1 682 ? 39.029 64.590 -42.058 1.00 30.51 ? 682 ASN A O 1 ATOM 5432 C CB . ASN A 1 682 ? 41.794 64.245 -42.778 1.00 30.76 ? 682 ASN A CB 1 ATOM 5433 C CG . ASN A 1 682 ? 42.928 64.242 -43.767 1.00 35.30 ? 682 ASN A CG 1 ATOM 5434 O OD1 . ASN A 1 682 ? 42.942 65.017 -44.713 1.00 44.05 ? 682 ASN A OD1 1 ATOM 5435 N ND2 . ASN A 1 682 ? 43.888 63.355 -43.558 1.00 39.77 ? 682 ASN A ND2 1 ATOM 5436 N N . GLY A 1 683 ? 39.832 66.181 -40.692 1.00 22.69 ? 683 GLY A N 1 ATOM 5437 C CA . GLY A 1 683 ? 39.100 65.782 -39.506 1.00 21.43 ? 683 GLY A CA 1 ATOM 5438 C C . GLY A 1 683 ? 37.648 66.136 -39.705 1.00 16.07 ? 683 GLY A C 1 ATOM 5439 O O . GLY A 1 683 ? 37.244 66.363 -40.826 1.00 17.92 ? 683 GLY A O 1 ATOM 5440 N N . PRO A 1 684 ? 36.871 66.209 -38.631 1.00 14.59 ? 684 PRO A N 1 ATOM 5441 C CA . PRO A 1 684 ? 35.440 66.481 -38.787 1.00 13.32 ? 684 PRO A CA 1 ATOM 5442 C C . PRO A 1 684 ? 35.165 67.918 -39.229 1.00 11.79 ? 684 PRO A C 1 ATOM 5443 O O . PRO A 1 684 ? 35.972 68.810 -39.025 1.00 13.28 ? 684 PRO A O 1 ATOM 5444 C CB . PRO A 1 684 ? 34.881 66.230 -37.385 1.00 15.70 ? 684 PRO A CB 1 ATOM 5445 C CG . PRO A 1 684 ? 36.042 66.463 -36.476 1.00 20.38 ? 684 PRO A CG 1 ATOM 5446 C CD . PRO A 1 684 ? 37.230 65.972 -37.223 1.00 16.67 ? 684 PRO A CD 1 ATOM 5447 N N . THR A 1 685 ? 34.013 68.117 -39.848 1.00 11.55 ? 685 THR A N 1 ATOM 5448 C CA . THR A 1 685 ? 33.524 69.447 -40.156 1.00 11.11 ? 685 THR A CA 1 ATOM 5449 C C . THR A 1 685 ? 32.486 69.819 -39.108 1.00 11.74 ? 685 THR A C 1 ATOM 5450 O O . THR A 1 685 ? 31.538 69.082 -38.891 1.00 12.50 ? 685 THR A O 1 ATOM 5451 C CB . THR A 1 685 ? 32.888 69.476 -41.550 1.00 12.94 ? 685 THR A CB 1 ATOM 5452 O OG1 . THR A 1 685 ? 33.863 69.087 -42.517 1.00 15.65 ? 685 THR A OG1 1 ATOM 5453 C CG2 . THR A 1 685 ? 32.372 70.866 -41.886 1.00 14.92 ? 685 THR A CG2 1 ATOM 5454 N N . LEU A 1 686 ? 32.691 70.951 -38.448 1.00 9.48 ? 686 LEU A N 1 ATOM 5455 C CA . LEU A 1 686 ? 31.802 71.398 -37.385 1.00 10.25 ? 686 LEU A CA 1 ATOM 5456 C C . LEU A 1 686 ? 31.008 72.610 -37.867 1.00 10.40 ? 686 LEU A C 1 ATOM 5457 O O . LEU A 1 686 ? 31.575 73.535 -38.452 1.00 11.32 ? 686 LEU A O 1 ATOM 5458 C CB . LEU A 1 686 ? 32.608 71.782 -36.139 1.00 10.26 ? 686 LEU A CB 1 ATOM 5459 C CG . LEU A 1 686 ? 33.570 70.792 -35.467 1.00 16.50 ? 686 LEU A CG 1 ATOM 5460 C CD1 . LEU A 1 686 ? 33.765 71.121 -33.994 1.00 15.37 ? 686 LEU A CD1 1 ATOM 5461 C CD2 . LEU A 1 686 ? 33.230 69.348 -35.652 1.00 17.63 ? 686 LEU A CD2 1 ATOM 5462 N N . ALA A 1 687 ? 29.704 72.608 -37.614 1.00 9.23 ? 687 ALA A N 1 ATOM 5463 C CA . ALA A 1 687 ? 28.889 73.757 -37.967 1.00 10.17 ? 687 ALA A CA 1 ATOM 5464 C C . ALA A 1 687 ? 28.429 74.430 -36.689 1.00 10.73 ? 687 ALA A C 1 ATOM 5465 O O . ALA A 1 687 ? 28.098 73.741 -35.693 1.00 10.34 ? 687 ALA A O 1 ATOM 5466 C CB . ALA A 1 687 ? 27.653 73.297 -38.815 1.00 11.44 ? 687 ALA A CB 1 ATOM 5467 N N . PHE A 1 688 ? 28.386 75.763 -36.704 1.00 10.52 ? 688 PHE A N 1 ATOM 5468 C CA . PHE A 1 688 ? 28.030 76.570 -35.552 1.00 8.86 ? 688 PHE A CA 1 ATOM 5469 C C . PHE A 1 688 ? 26.857 77.490 -35.818 1.00 10.20 ? 688 PHE A C 1 ATOM 5470 O O . PHE A 1 688 ? 26.710 77.973 -36.959 1.00 11.89 ? 688 PHE A O 1 ATOM 5471 C CB . PHE A 1 688 ? 29.207 77.472 -35.152 1.00 10.19 ? 688 PHE A CB 1 ATOM 5472 C CG . PHE A 1 688 ? 30.422 76.699 -34.776 1.00 8.90 ? 688 PHE A CG 1 ATOM 5473 C CD1 . PHE A 1 688 ? 31.268 76.208 -35.741 1.00 9.96 ? 688 PHE A CD1 1 ATOM 5474 C CD2 . PHE A 1 688 ? 30.693 76.406 -33.444 1.00 8.69 ? 688 PHE A CD2 1 ATOM 5475 C CE1 . PHE A 1 688 ? 32.394 75.392 -35.437 1.00 8.73 ? 688 PHE A CE1 1 ATOM 5476 C CE2 . PHE A 1 688 ? 31.817 75.599 -33.146 1.00 8.48 ? 688 PHE A CE2 1 ATOM 5477 C CZ . PHE A 1 688 ? 32.655 75.096 -34.125 1.00 8.50 ? 688 PHE A CZ 1 ATOM 5478 N N . SER A 1 689 ? 26.041 77.756 -34.834 1.00 10.68 ? 689 SER A N 1 ATOM 5479 C CA . SER A 1 689 ? 24.917 78.688 -34.935 1.00 11.68 ? 689 SER A CA 1 ATOM 5480 C C . SER A 1 689 ? 25.498 80.129 -34.969 1.00 11.49 ? 689 SER A C 1 ATOM 5481 O O . SER A 1 689 ? 26.683 80.377 -34.729 1.00 10.77 ? 689 SER A O 1 ATOM 5482 C CB . SER A 1 689 ? 24.023 78.570 -33.689 1.00 10.85 ? 689 SER A CB 1 ATOM 5483 O OG . SER A 1 689 ? 24.638 79.144 -32.549 1.00 12.01 ? 689 SER A OG 1 ATOM 5484 N N . GLU A 1 690 ? 24.621 81.092 -35.261 1.00 12.15 ? 690 GLU A N 1 ATOM 5485 C CA . GLU A 1 690 ? 25.040 82.489 -35.225 1.00 11.45 ? 690 GLU A CA 1 ATOM 5486 C C . GLU A 1 690 ? 25.416 82.960 -33.839 1.00 11.48 ? 690 GLU A C 1 ATOM 5487 O O . GLU A 1 690 ? 25.986 84.049 -33.685 1.00 12.25 ? 690 GLU A O 1 ATOM 5488 C CB . GLU A 1 690 ? 23.961 83.388 -35.829 1.00 17.18 ? 690 GLU A CB 1 ATOM 5489 C CG . GLU A 1 690 ? 22.735 83.613 -35.080 1.00 19.62 ? 690 GLU A CG 1 ATOM 5490 C CD . GLU A 1 690 ? 21.939 84.723 -35.765 1.00 26.73 ? 690 GLU A CD 1 ATOM 5491 O OE1 . GLU A 1 690 ? 21.472 84.453 -36.902 1.00 30.30 ? 690 GLU A OE1 1 ATOM 5492 O OE2 . GLU A 1 690 ? 21.811 85.860 -35.201 1.00 35.05 ? 690 GLU A OE2 1 ATOM 5493 N N . GLN A 1 691 ? 25.064 82.172 -32.818 1.00 12.07 ? 691 GLN A N 1 ATOM 5494 C CA . GLN A 1 691 ? 25.516 82.522 -31.461 1.00 12.17 ? 691 GLN A CA 1 ATOM 5495 C C . GLN A 1 691 ? 26.861 81.842 -31.113 1.00 9.37 ? 691 GLN A C 1 ATOM 5496 O O . GLN A 1 691 ? 27.272 81.920 -29.935 1.00 14.15 ? 691 GLN A O 1 ATOM 5497 C CB . GLN A 1 691 ? 24.502 82.134 -30.377 1.00 13.31 ? 691 GLN A CB 1 ATOM 5498 C CG . GLN A 1 691 ? 23.217 82.881 -30.457 1.00 19.08 ? 691 GLN A CG 1 ATOM 5499 C CD . GLN A 1 691 ? 22.211 81.870 -30.623 1.00 32.90 ? 691 GLN A CD 1 ATOM 5500 O OE1 . GLN A 1 691 ? 21.759 81.227 -29.635 1.00 30.15 ? 691 GLN A OE1 1 ATOM 5501 N NE2 . GLN A 1 691 ? 21.889 81.606 -31.885 1.00 29.83 ? 691 GLN A NE2 1 ATOM 5502 N N . GLY A 1 692 ? 27.509 81.185 -32.052 1.00 9.42 ? 692 GLY A N 1 ATOM 5503 C CA . GLY A 1 692 ? 28.835 80.649 -31.792 1.00 11.23 ? 692 GLY A CA 1 ATOM 5504 C C . GLY A 1 692 ? 28.839 79.299 -31.121 1.00 9.15 ? 692 GLY A C 1 ATOM 5505 O O . GLY A 1 692 ? 29.875 78.870 -30.653 1.00 11.10 ? 692 GLY A O 1 ATOM 5506 N N . LEU A 1 693 ? 27.703 78.613 -31.110 1.00 9.00 ? 693 LEU A N 1 ATOM 5507 C CA . LEU A 1 693 ? 27.592 77.302 -30.444 1.00 9.73 ? 693 LEU A CA 1 ATOM 5508 C C . LEU A 1 693 ? 27.459 76.210 -31.445 1.00 10.19 ? 693 LEU A C 1 ATOM 5509 O O . LEU A 1 693 ? 26.733 76.332 -32.461 1.00 9.66 ? 693 LEU A O 1 ATOM 5510 C CB . LEU A 1 693 ? 26.387 77.311 -29.529 1.00 11.45 ? 693 LEU A CB 1 ATOM 5511 C CG . LEU A 1 693 ? 26.536 78.278 -28.349 1.00 12.91 ? 693 LEU A CG 1 ATOM 5512 C CD1 . LEU A 1 693 ? 25.136 78.772 -27.970 1.00 19.21 ? 693 LEU A CD1 1 ATOM 5513 C CD2 . LEU A 1 693 ? 27.145 77.613 -27.160 1.00 15.87 ? 693 LEU A CD2 1 ATOM 5514 N N . LEU A 1 694 ? 28.133 75.093 -31.187 1.00 9.01 ? 694 LEU A N 1 ATOM 5515 C CA . LEU A 1 694 ? 28.052 73.958 -32.091 1.00 8.36 ? 694 LEU A CA 1 ATOM 5516 C C . LEU A 1 694 ? 26.619 73.557 -32.357 1.00 7.49 ? 694 LEU A C 1 ATOM 5517 O O . LEU A 1 694 ? 25.776 73.544 -31.435 1.00 8.36 ? 694 LEU A O 1 ATOM 5518 C CB . LEU A 1 694 ? 28.757 72.748 -31.390 1.00 10.88 ? 694 LEU A CB 1 ATOM 5519 C CG . LEU A 1 694 ? 28.959 71.488 -32.239 1.00 10.83 ? 694 LEU A CG 1 ATOM 5520 C CD1 . LEU A 1 694 ? 29.947 71.753 -33.372 1.00 11.23 ? 694 LEU A CD1 1 ATOM 5521 C CD2 . LEU A 1 694 ? 29.502 70.352 -31.334 1.00 11.85 ? 694 LEU A CD2 1 ATOM 5522 N N . LYS A 1 695 ? 26.345 73.210 -33.639 1.00 9.16 ? 695 LYS A N 1 ATOM 5523 C CA . LYS A 1 695 ? 25.039 72.652 -33.995 1.00 9.77 ? 695 LYS A CA 1 ATOM 5524 C C . LYS A 1 695 ? 25.159 71.325 -34.701 1.00 9.62 ? 695 LYS A C 1 ATOM 5525 O O . LYS A 1 695 ? 24.173 70.571 -34.635 1.00 11.04 ? 695 LYS A O 1 ATOM 5526 C CB . LYS A 1 695 ? 24.171 73.638 -34.813 1.00 14.80 ? 695 LYS A CB 1 ATOM 5527 C CG . LYS A 1 695 ? 24.751 74.009 -36.101 1.00 23.52 ? 695 LYS A CG 1 ATOM 5528 C CD . LYS A 1 695 ? 23.933 75.212 -36.685 1.00 29.86 ? 695 LYS A CD 1 ATOM 5529 C CE . LYS A 1 695 ? 22.440 75.044 -36.478 1.00 35.26 ? 695 LYS A CE 1 ATOM 5530 N NZ . LYS A 1 695 ? 21.908 74.251 -37.628 1.00 39.70 ? 695 LYS A NZ 1 ATOM 5531 N N . SER A 1 696 ? 26.272 70.989 -35.312 1.00 8.97 ? 696 SER A N 1 ATOM 5532 C CA . SER A 1 696 ? 26.389 69.650 -35.967 1.00 10.51 ? 696 SER A CA 1 ATOM 5533 C C . SER A 1 696 ? 27.817 69.262 -36.180 1.00 11.51 ? 696 SER A C 1 ATOM 5534 O O . SER A 1 696 ? 28.729 70.151 -36.241 1.00 10.61 ? 696 SER A O 1 ATOM 5535 C CB . SER A 1 696 ? 25.639 69.617 -37.337 1.00 11.02 ? 696 SER A CB 1 ATOM 5536 O OG . SER A 1 696 ? 26.244 70.411 -38.333 1.00 13.72 ? 696 SER A OG 1 ATOM 5537 N N . ILE A 1 697 ? 28.062 67.939 -36.334 1.00 10.23 ? 697 ILE A N 1 ATOM 5538 C CA . ILE A 1 697 ? 29.378 67.399 -36.601 1.00 11.96 ? 697 ILE A CA 1 ATOM 5539 C C . ILE A 1 697 ? 29.243 66.453 -37.780 1.00 12.97 ? 697 ILE A C 1 ATOM 5540 O O . ILE A 1 697 ? 28.362 65.571 -37.749 1.00 12.98 ? 697 ILE A O 1 ATOM 5541 C CB . ILE A 1 697 ? 29.937 66.595 -35.369 1.00 11.63 ? 697 ILE A CB 1 ATOM 5542 C CG1 . ILE A 1 697 ? 30.034 67.519 -34.158 1.00 10.93 ? 697 ILE A CG1 1 ATOM 5543 C CG2 . ILE A 1 697 ? 31.283 65.932 -35.702 1.00 11.76 ? 697 ILE A CG2 1 ATOM 5544 C CD1 . ILE A 1 697 ? 30.527 66.750 -32.864 1.00 11.84 ? 697 ILE A CD1 1 ATOM 5545 N N . GLN A 1 698 ? 30.060 66.662 -38.786 1.00 11.32 ? 698 GLN A N 1 ATOM 5546 C CA . GLN A 1 698 ? 30.083 65.773 -39.911 1.00 12.14 ? 698 GLN A CA 1 ATOM 5547 C C . GLN A 1 698 ? 31.409 65.052 -39.923 1.00 13.28 ? 698 GLN A C 1 ATOM 5548 O O . GLN A 1 698 ? 32.415 65.673 -40.137 1.00 13.91 ? 698 GLN A O 1 ATOM 5549 C CB . GLN A 1 698 ? 29.911 66.570 -41.198 1.00 14.40 ? 698 GLN A CB 1 ATOM 5550 C CG . GLN A 1 698 ? 29.926 65.675 -42.436 1.00 18.06 ? 698 GLN A CG 1 ATOM 5551 C CD . GLN A 1 698 ? 30.071 66.454 -43.719 1.00 19.44 ? 698 GLN A CD 1 ATOM 5552 O OE1 . GLN A 1 698 ? 30.726 67.477 -43.761 1.00 25.75 ? 698 GLN A OE1 1 ATOM 5553 N NE2 . GLN A 1 698 ? 29.438 65.973 -44.768 1.00 21.36 ? 698 GLN A NE2 1 ATOM 5554 N N . LEU A 1 699 ? 31.413 63.741 -39.716 1.00 14.21 ? 699 LEU A N 1 ATOM 5555 C CA . LEU A 1 699 ? 32.686 63.054 -39.560 1.00 15.57 ? 699 LEU A CA 1 ATOM 5556 C C . LEU A 1 699 ? 33.594 63.006 -40.801 1.00 19.75 ? 699 LEU A C 1 ATOM 5557 O O . LEU A 1 699 ? 34.811 63.186 -40.684 1.00 22.18 ? 699 LEU A O 1 ATOM 5558 C CB . LEU A 1 699 ? 32.427 61.640 -38.991 1.00 18.76 ? 699 LEU A CB 1 ATOM 5559 C CG . LEU A 1 699 ? 31.809 61.644 -37.578 1.00 17.28 ? 699 LEU A CG 1 ATOM 5560 C CD1 . LEU A 1 699 ? 31.598 60.186 -37.122 1.00 20.15 ? 699 LEU A CD1 1 ATOM 5561 C CD2 . LEU A 1 699 ? 32.694 62.359 -36.585 1.00 19.52 ? 699 LEU A CD2 1 ATOM 5562 N N . THR A 1 700 ? 32.987 62.836 -41.975 1.00 20.25 ? 700 THR A N 1 ATOM 5563 C CA . THR A 1 700 ? 33.777 62.807 -43.204 1.00 27.44 ? 700 THR A CA 1 ATOM 5564 C C . THR A 1 700 ? 33.031 63.527 -44.305 1.00 27.59 ? 700 THR A C 1 ATOM 5565 O O . THR A 1 700 ? 31.890 63.949 -44.119 1.00 28.16 ? 700 THR A O 1 ATOM 5566 C CB . THR A 1 700 ? 34.079 61.350 -43.654 1.00 28.06 ? 700 THR A CB 1 ATOM 5567 O OG1 . THR A 1 700 ? 32.846 60.630 -43.811 1.00 33.82 ? 700 THR A OG1 1 ATOM 5568 C CG2 . THR A 1 700 ? 34.953 60.648 -42.618 1.00 28.65 ? 700 THR A CG2 1 ATOM 5569 N N . GLN A 1 701 ? 33.683 63.664 -45.458 1.00 33.69 ? 701 GLN A N 1 ATOM 5570 C CA . GLN A 1 701 ? 33.126 64.370 -46.620 1.00 36.45 ? 701 GLN A CA 1 ATOM 5571 C C . GLN A 1 701 ? 31.756 63.830 -47.039 1.00 36.02 ? 701 GLN A C 1 ATOM 5572 O O . GLN A 1 701 ? 30.856 64.598 -47.329 1.00 38.67 ? 701 GLN A O 1 ATOM 5573 C CB . GLN A 1 701 ? 34.105 64.357 -47.810 1.00 39.82 ? 701 GLN A CB 1 ATOM 5574 C CG . GLN A 1 701 ? 35.343 65.213 -47.632 1.00 42.97 ? 701 GLN A CG 1 ATOM 5575 C CD . GLN A 1 701 ? 35.122 66.661 -48.002 1.00 46.11 ? 701 GLN A CD 1 ATOM 5576 O OE1 . GLN A 1 701 ? 34.081 67.245 -47.705 1.00 46.00 ? 701 GLN A OE1 1 ATOM 5577 N NE2 . GLN A 1 701 ? 36.111 67.256 -48.635 1.00 46.69 ? 701 GLN A NE2 1 ATOM 5578 N N . ASP A 1 702 ? 31.592 62.515 -47.021 1.00 36.96 ? 702 ASP A N 1 ATOM 5579 C CA . ASP A 1 702 ? 30.334 61.885 -47.436 1.00 41.32 ? 702 ASP A CA 1 ATOM 5580 C C . ASP A 1 702 ? 29.204 61.837 -46.419 1.00 41.01 ? 702 ASP A C 1 ATOM 5581 O O . ASP A 1 702 ? 28.020 61.856 -46.774 1.00 41.01 ? 702 ASP A O 1 ATOM 5582 C CB . ASP A 1 702 ? 30.608 60.438 -47.903 1.00 43.85 ? 702 ASP A CB 1 ATOM 5583 C CG . ASP A 1 702 ? 31.108 59.524 -46.768 1.00 47.43 ? 702 ASP A CG 1 ATOM 5584 O OD1 . ASP A 1 702 ? 32.190 59.813 -46.193 1.00 49.18 ? 702 ASP A OD1 1 ATOM 5585 O OD2 . ASP A 1 702 ? 30.420 58.513 -46.463 1.00 49.67 ? 702 ASP A OD2 1 ATOM 5586 N N . SER A 1 703 ? 29.546 62.006 -45.144 1.00 36.88 ? 703 SER A N 1 ATOM 5587 C CA . SER A 1 703 ? 28.645 61.643 -44.068 1.00 30.36 ? 703 SER A CA 1 ATOM 5588 C C . SER A 1 703 ? 27.625 62.711 -43.664 1.00 24.00 ? 703 SER A C 1 ATOM 5589 O O . SER A 1 703 ? 27.744 63.863 -44.039 1.00 24.46 ? 703 SER A O 1 ATOM 5590 C CB . SER A 1 703 ? 29.441 61.135 -42.870 1.00 31.98 ? 703 SER A CB 1 ATOM 5591 O OG . SER A 1 703 ? 30.216 62.173 -42.312 1.00 28.34 ? 703 SER A OG 1 ATOM 5592 N N . PRO A 1 704 ? 26.622 62.289 -42.906 1.00 23.53 ? 704 PRO A N 1 ATOM 5593 C CA . PRO A 1 704 ? 25.563 63.151 -42.405 1.00 22.20 ? 704 PRO A CA 1 ATOM 5594 C C . PRO A 1 704 ? 26.095 64.238 -41.435 1.00 18.71 ? 704 PRO A C 1 ATOM 5595 O O . PRO A 1 704 ? 27.121 64.036 -40.722 1.00 20.54 ? 704 PRO A O 1 ATOM 5596 C CB . PRO A 1 704 ? 24.669 62.185 -41.629 1.00 25.44 ? 704 PRO A CB 1 ATOM 5597 C CG . PRO A 1 704 ? 24.923 60.878 -42.323 1.00 23.86 ? 704 PRO A CG 1 ATOM 5598 C CD . PRO A 1 704 ? 26.365 60.873 -42.566 1.00 26.03 ? 704 PRO A CD 1 ATOM 5599 N N . HIS A 1 705 ? 25.447 65.402 -41.493 1.00 18.67 ? 705 HIS A N 1 ATOM 5600 C CA . HIS A 1 705 ? 25.739 66.442 -40.498 1.00 16.69 ? 705 HIS A CA 1 ATOM 5601 C C . HIS A 1 705 ? 24.895 66.010 -39.293 1.00 17.91 ? 705 HIS A C 1 ATOM 5602 O O . HIS A 1 705 ? 23.699 66.262 -39.213 1.00 19.35 ? 705 HIS A O 1 ATOM 5603 C CB . HIS A 1 705 ? 25.323 67.816 -41.033 1.00 19.91 ? 705 HIS A CB 1 ATOM 5604 C CG . HIS A 1 705 ? 26.190 68.294 -42.159 1.00 23.20 ? 705 HIS A CG 1 ATOM 5605 N ND1 . HIS A 1 705 ? 27.313 69.076 -41.966 1.00 24.30 ? 705 HIS A ND1 1 ATOM 5606 C CD2 . HIS A 1 705 ? 26.129 68.047 -43.490 1.00 29.26 ? 705 HIS A CD2 1 ATOM 5607 C CE1 . HIS A 1 705 ? 27.908 69.286 -43.130 1.00 31.19 ? 705 HIS A CE1 1 ATOM 5608 N NE2 . HIS A 1 705 ? 27.207 68.673 -44.072 1.00 28.54 ? 705 HIS A NE2 1 ATOM 5609 N N . VAL A 1 706 ? 25.546 65.375 -38.300 1.00 13.26 ? 706 VAL A N 1 ATOM 5610 C CA . VAL A 1 706 ? 24.821 64.860 -37.143 1.00 12.92 ? 706 VAL A CA 1 ATOM 5611 C C . VAL A 1 706 ? 24.484 65.962 -36.154 1.00 10.95 ? 706 VAL A C 1 ATOM 5612 O O . VAL A 1 706 ? 25.407 66.674 -35.763 1.00 11.82 ? 706 VAL A O 1 ATOM 5613 C CB . VAL A 1 706 ? 25.719 63.792 -36.408 1.00 12.09 ? 706 VAL A CB 1 ATOM 5614 C CG1 . VAL A 1 706 ? 24.971 63.271 -35.161 1.00 12.35 ? 706 VAL A CG1 1 ATOM 5615 C CG2 . VAL A 1 706 ? 26.164 62.663 -37.404 1.00 14.07 ? 706 VAL A CG2 1 ATOM 5616 N N . PRO A 1 707 ? 23.219 66.168 -35.779 1.00 10.04 ? 707 PRO A N 1 ATOM 5617 C CA . PRO A 1 707 ? 22.861 67.221 -34.821 1.00 12.04 ? 707 PRO A CA 1 ATOM 5618 C C . PRO A 1 707 ? 23.516 66.996 -33.470 1.00 11.36 ? 707 PRO A C 1 ATOM 5619 O O . PRO A 1 707 ? 23.355 65.941 -32.850 1.00 12.24 ? 707 PRO A O 1 ATOM 5620 C CB . PRO A 1 707 ? 21.336 67.134 -34.706 1.00 12.03 ? 707 PRO A CB 1 ATOM 5621 C CG . PRO A 1 707 ? 20.919 66.431 -36.008 1.00 16.20 ? 707 PRO A CG 1 ATOM 5622 C CD . PRO A 1 707 ? 22.019 65.437 -36.269 1.00 12.31 ? 707 PRO A CD 1 ATOM 5623 N N . VAL A 1 708 ? 24.328 67.985 -33.073 1.00 10.63 ? 708 VAL A N 1 ATOM 5624 C CA . VAL A 1 708 ? 25.034 67.956 -31.759 1.00 9.99 ? 708 VAL A CA 1 ATOM 5625 C C . VAL A 1 708 ? 25.012 69.435 -31.377 1.00 9.43 ? 708 VAL A C 1 ATOM 5626 O O . VAL A 1 708 ? 25.759 70.266 -31.976 1.00 10.55 ? 708 VAL A O 1 ATOM 5627 C CB . VAL A 1 708 ? 26.480 67.430 -31.878 1.00 10.48 ? 708 VAL A CB 1 ATOM 5628 C CG1 . VAL A 1 708 ? 27.154 67.445 -30.449 1.00 12.08 ? 708 VAL A CG1 1 ATOM 5629 C CG2 . VAL A 1 708 ? 26.490 65.954 -32.432 1.00 12.86 ? 708 VAL A CG2 1 ATOM 5630 N N . HIS A 1 709 ? 24.182 69.801 -30.417 1.00 9.25 ? 709 HIS A N 1 ATOM 5631 C CA . HIS A 1 709 ? 24.077 71.208 -30.073 1.00 10.46 ? 709 HIS A CA 1 ATOM 5632 C C . HIS A 1 709 ? 24.480 71.496 -28.636 1.00 11.67 ? 709 HIS A C 1 ATOM 5633 O O . HIS A 1 709 ? 23.989 70.843 -27.736 1.00 11.04 ? 709 HIS A O 1 ATOM 5634 C CB A HIS A 1 709 ? 22.651 71.635 -30.364 0.50 14.05 ? 709 HIS A CB 1 ATOM 5635 C CB B HIS A 1 709 ? 22.567 71.527 -30.258 0.50 14.10 ? 709 HIS A CB 1 ATOM 5636 C CG A HIS A 1 709 ? 22.392 73.084 -30.077 0.50 24.00 ? 709 HIS A CG 1 ATOM 5637 C CG B HIS A 1 709 ? 22.039 71.805 -31.669 0.50 26.91 ? 709 HIS A CG 1 ATOM 5638 N ND1 A HIS A 1 709 ? 23.202 74.097 -30.546 0.50 32.24 ? 709 HIS A ND1 1 ATOM 5639 N ND1 B HIS A 1 709 ? 21.850 70.801 -32.592 0.50 36.18 ? 709 HIS A ND1 1 ATOM 5640 C CD2 A HIS A 1 709 ? 21.422 73.687 -29.356 0.50 28.07 ? 709 HIS A CD2 1 ATOM 5641 C CD2 B HIS A 1 709 ? 21.652 72.951 -32.282 0.50 34.76 ? 709 HIS A CD2 1 ATOM 5642 C CE1 A HIS A 1 709 ? 22.728 75.261 -30.145 0.50 25.05 ? 709 HIS A CE1 1 ATOM 5643 C CE1 B HIS A 1 709 ? 21.406 71.315 -33.723 0.50 33.34 ? 709 HIS A CE1 1 ATOM 5644 N NE2 A HIS A 1 709 ? 21.657 75.037 -29.411 0.50 31.39 ? 709 HIS A NE2 1 ATOM 5645 N NE2 B HIS A 1 709 ? 21.255 72.619 -33.555 0.50 28.82 ? 709 HIS A NE2 1 ATOM 5646 N N . PHE A 1 710 ? 25.343 72.491 -28.434 1.00 9.30 ? 710 PHE A N 1 ATOM 5647 C CA . PHE A 1 710 ? 25.667 72.939 -27.079 1.00 7.34 ? 710 PHE A CA 1 ATOM 5648 C C . PHE A 1 710 ? 24.635 74.019 -26.672 1.00 9.33 ? 710 PHE A C 1 ATOM 5649 O O . PHE A 1 710 ? 24.264 74.909 -27.506 1.00 10.09 ? 710 PHE A O 1 ATOM 5650 C CB . PHE A 1 710 ? 27.065 73.583 -26.995 1.00 10.49 ? 710 PHE A CB 1 ATOM 5651 C CG . PHE A 1 710 ? 28.174 72.604 -26.662 1.00 10.45 ? 710 PHE A CG 1 ATOM 5652 C CD1 . PHE A 1 710 ? 28.134 71.891 -25.462 1.00 12.19 ? 710 PHE A CD1 1 ATOM 5653 C CD2 . PHE A 1 710 ? 29.253 72.408 -27.526 1.00 12.81 ? 710 PHE A CD2 1 ATOM 5654 C CE1 . PHE A 1 710 ? 29.155 70.974 -25.078 1.00 13.36 ? 710 PHE A CE1 1 ATOM 5655 C CE2 . PHE A 1 710 ? 30.293 71.485 -27.133 1.00 12.15 ? 710 PHE A CE2 1 ATOM 5656 C CZ . PHE A 1 710 ? 30.206 70.794 -25.896 1.00 13.77 ? 710 PHE A CZ 1 ATOM 5657 N N . LYS A 1 711 ? 24.214 73.993 -25.419 1.00 8.15 ? 711 LYS A N 1 ATOM 5658 C CA . LYS A 1 711 ? 23.298 74.959 -24.869 1.00 10.32 ? 711 LYS A CA 1 ATOM 5659 C C . LYS A 1 711 ? 23.661 75.202 -23.427 1.00 10.22 ? 711 LYS A C 1 ATOM 5660 O O . LYS A 1 711 ? 23.942 74.246 -22.705 1.00 12.34 ? 711 LYS A O 1 ATOM 5661 C CB . LYS A 1 711 ? 21.851 74.400 -24.952 1.00 11.52 ? 711 LYS A CB 1 ATOM 5662 C CG . LYS A 1 711 ? 20.784 75.387 -24.423 1.00 15.37 ? 711 LYS A CG 1 ATOM 5663 C CD . LYS A 1 711 ? 19.377 74.836 -24.529 1.00 18.36 ? 711 LYS A CD 1 ATOM 5664 C CE . LYS A 1 711 ? 18.986 74.755 -26.006 1.00 18.60 ? 711 LYS A CE 1 ATOM 5665 N NZ . LYS A 1 711 ? 17.618 74.114 -26.052 1.00 21.23 ? 711 LYS A NZ 1 ATOM 5666 N N . PHE A 1 712 ? 23.628 76.430 -22.961 1.00 8.45 ? 712 PHE A N 1 ATOM 5667 C CA . PHE A 1 712 ? 23.842 76.753 -21.572 1.00 7.70 ? 712 PHE A CA 1 ATOM 5668 C C . PHE A 1 712 ? 22.543 77.091 -20.891 1.00 7.67 ? 712 PHE A C 1 ATOM 5669 O O . PHE A 1 712 ? 21.698 77.856 -21.442 1.00 9.58 ? 712 PHE A O 1 ATOM 5670 C CB . PHE A 1 712 ? 24.836 77.933 -21.432 1.00 9.80 ? 712 PHE A CB 1 ATOM 5671 C CG . PHE A 1 712 ? 26.253 77.527 -21.737 1.00 8.59 ? 712 PHE A CG 1 ATOM 5672 C CD1 . PHE A 1 712 ? 26.738 77.539 -23.039 1.00 9.47 ? 712 PHE A CD1 1 ATOM 5673 C CD2 . PHE A 1 712 ? 27.093 77.058 -20.709 1.00 9.25 ? 712 PHE A CD2 1 ATOM 5674 C CE1 . PHE A 1 712 ? 28.028 77.079 -23.338 1.00 9.09 ? 712 PHE A CE1 1 ATOM 5675 C CE2 . PHE A 1 712 ? 28.357 76.616 -20.990 1.00 8.28 ? 712 PHE A CE2 1 ATOM 5676 C CZ . PHE A 1 712 ? 28.835 76.614 -22.285 1.00 8.87 ? 712 PHE A CZ 1 ATOM 5677 N N . LEU A 1 713 ? 22.335 76.553 -19.707 1.00 7.59 ? 713 LEU A N 1 ATOM 5678 C CA . LEU A 1 713 ? 21.106 76.763 -18.952 1.00 8.11 ? 713 LEU A CA 1 ATOM 5679 C C . LEU A 1 713 ? 21.420 77.048 -17.506 1.00 9.06 ? 713 LEU A C 1 ATOM 5680 O O . LEU A 1 713 ? 22.598 76.937 -17.058 1.00 8.56 ? 713 LEU A O 1 ATOM 5681 C CB . LEU A 1 713 ? 20.175 75.525 -19.046 1.00 9.12 ? 713 LEU A CB 1 ATOM 5682 C CG . LEU A 1 713 ? 19.834 75.078 -20.468 1.00 8.40 ? 713 LEU A CG 1 ATOM 5683 C CD1 . LEU A 1 713 ? 20.704 73.882 -20.854 1.00 11.96 ? 713 LEU A CD1 1 ATOM 5684 C CD2 . LEU A 1 713 ? 18.343 74.638 -20.544 1.00 12.10 ? 713 LEU A CD2 1 ATOM 5685 N N . LYS A 1 714 ? 20.411 77.463 -16.762 1.00 8.84 ? 714 LYS A N 1 ATOM 5686 C CA . LYS A 1 714 ? 20.586 77.727 -15.354 1.00 8.87 ? 714 LYS A CA 1 ATOM 5687 C C . LYS A 1 714 ? 19.546 77.039 -14.492 1.00 9.86 ? 714 LYS A C 1 ATOM 5688 O O . LYS A 1 714 ? 18.344 76.992 -14.850 1.00 11.33 ? 714 LYS A O 1 ATOM 5689 C CB . LYS A 1 714 ? 20.508 79.243 -15.071 1.00 14.00 ? 714 LYS A CB 1 ATOM 5690 C CG . LYS A 1 714 ? 19.390 79.935 -15.718 1.00 23.87 ? 714 LYS A CG 1 ATOM 5691 C CD . LYS A 1 714 ? 19.347 81.415 -15.266 1.00 30.15 ? 714 LYS A CD 1 ATOM 5692 C CE . LYS A 1 714 ? 20.634 82.182 -15.547 1.00 33.06 ? 714 LYS A CE 1 ATOM 5693 N NZ . LYS A 1 714 ? 20.594 83.669 -15.113 1.00 39.20 ? 714 LYS A NZ 1 ATOM 5694 N N . TYR A 1 715 ? 20.003 76.498 -13.368 1.00 8.63 ? 715 TYR A N 1 ATOM 5695 C CA . TYR A 1 715 ? 19.130 75.989 -12.343 1.00 7.82 ? 715 TYR A CA 1 ATOM 5696 C C . TYR A 1 715 ? 19.077 77.048 -11.240 1.00 10.01 ? 715 TYR A C 1 ATOM 5697 O O . TYR A 1 715 ? 20.050 77.754 -10.975 1.00 10.28 ? 715 TYR A O 1 ATOM 5698 C CB . TYR A 1 715 ? 19.666 74.684 -11.714 1.00 7.36 ? 715 TYR A CB 1 ATOM 5699 C CG . TYR A 1 715 ? 19.598 73.475 -12.557 1.00 7.59 ? 715 TYR A CG 1 ATOM 5700 C CD1 . TYR A 1 715 ? 18.413 72.752 -12.635 1.00 7.85 ? 715 TYR A CD1 1 ATOM 5701 C CD2 . TYR A 1 715 ? 20.717 73.034 -13.288 1.00 8.49 ? 715 TYR A CD2 1 ATOM 5702 C CE1 . TYR A 1 715 ? 18.326 71.595 -13.404 1.00 7.94 ? 715 TYR A CE1 1 ATOM 5703 C CE2 . TYR A 1 715 ? 20.644 71.899 -14.090 1.00 8.31 ? 715 TYR A CE2 1 ATOM 5704 C CZ . TYR A 1 715 ? 19.427 71.168 -14.130 1.00 7.95 ? 715 TYR A CZ 1 ATOM 5705 O OH . TYR A 1 715 ? 19.350 69.994 -14.878 1.00 8.52 ? 715 TYR A OH 1 ATOM 5706 N N . GLY A 1 716 ? 17.920 77.113 -10.558 1.00 9.57 ? 716 GLY A N 1 ATOM 5707 C CA . GLY A 1 716 ? 17.753 78.010 -9.419 1.00 9.77 ? 716 GLY A CA 1 ATOM 5708 C C . GLY A 1 716 ? 17.609 77.220 -8.124 1.00 11.65 ? 716 GLY A C 1 ATOM 5709 O O . GLY A 1 716 ? 17.947 75.993 -8.047 1.00 12.19 ? 716 GLY A O 1 ATOM 5710 N N . VAL A 1 717 ? 17.121 77.885 -7.091 1.00 11.30 ? 717 VAL A N 1 ATOM 5711 C CA . VAL A 1 717 ? 16.976 77.312 -5.746 1.00 12.25 ? 717 VAL A CA 1 ATOM 5712 C C . VAL A 1 717 ? 15.527 77.470 -5.313 1.00 13.32 ? 717 VAL A C 1 ATOM 5713 O O . VAL A 1 717 ? 14.823 78.415 -5.761 1.00 16.84 ? 717 VAL A O 1 ATOM 5714 C CB . VAL A 1 717 ? 17.899 78.073 -4.786 1.00 12.66 ? 717 VAL A CB 1 ATOM 5715 C CG1 . VAL A 1 717 ? 17.721 77.677 -3.332 1.00 17.94 ? 717 VAL A CG1 1 ATOM 5716 C CG2 . VAL A 1 717 ? 19.363 77.828 -5.197 1.00 12.66 ? 717 VAL A CG2 1 ATOM 5717 N N . ARG A 1 718 ? 15.080 76.606 -4.416 1.00 11.17 ? 718 ARG A N 1 ATOM 5718 C CA . ARG A 1 718 ? 13.673 76.619 -3.939 1.00 12.81 ? 718 ARG A CA 1 ATOM 5719 C C . ARG A 1 718 ? 13.416 77.799 -3.056 1.00 18.65 ? 718 ARG A C 1 ATOM 5720 O O . ARG A 1 718 ? 14.249 78.179 -2.275 1.00 20.30 ? 718 ARG A O 1 ATOM 5721 C CB . ARG A 1 718 ? 13.343 75.295 -3.228 1.00 12.84 ? 718 ARG A CB 1 ATOM 5722 C CG . ARG A 1 718 ? 13.417 74.187 -4.233 1.00 12.44 ? 718 ARG A CG 1 ATOM 5723 C CD . ARG A 1 718 ? 13.443 72.813 -3.523 1.00 13.59 ? 718 ARG A CD 1 ATOM 5724 N NE . ARG A 1 718 ? 13.647 71.810 -4.542 1.00 13.01 ? 718 ARG A NE 1 ATOM 5725 C CZ . ARG A 1 718 ? 13.609 70.488 -4.337 1.00 12.91 ? 718 ARG A CZ 1 ATOM 5726 N NH1 . ARG A 1 718 ? 13.340 70.017 -3.121 1.00 14.24 ? 718 ARG A NH1 1 ATOM 5727 N NH2 . ARG A 1 718 ? 13.938 69.641 -5.296 1.00 16.23 ? 718 ARG A NH2 1 ATOM 5728 N N . SER A 1 719 ? 12.244 78.413 -3.212 1.00 20.64 ? 719 SER A N 1 ATOM 5729 C CA . SER A 1 719 ? 11.941 79.596 -2.411 1.00 25.62 ? 719 SER A CA 1 ATOM 5730 C C . SER A 1 719 ? 11.342 79.288 -1.042 1.00 27.14 ? 719 SER A C 1 ATOM 5731 O O . SER A 1 719 ? 11.180 80.174 -0.234 1.00 32.07 ? 719 SER A O 1 ATOM 5732 C CB . SER A 1 719 ? 11.029 80.530 -3.200 1.00 23.96 ? 719 SER A CB 1 ATOM 5733 O OG . SER A 1 719 ? 9.862 79.825 -3.531 1.00 29.67 ? 719 SER A OG 1 ATOM 5734 N N . HIS A 1 720 ? 10.994 78.030 -0.806 1.00 30.23 ? 720 HIS A N 1 ATOM 5735 C CA . HIS A 1 720 ? 10.530 77.579 0.495 1.00 33.10 ? 720 HIS A CA 1 ATOM 5736 C C . HIS A 1 720 ? 10.999 76.106 0.594 1.00 33.12 ? 720 HIS A C 1 ATOM 5737 O O . HIS A 1 720 ? 11.264 75.438 -0.426 1.00 33.64 ? 720 HIS A O 1 ATOM 5738 C CB . HIS A 1 720 ? 9.009 77.749 0.631 1.00 35.40 ? 720 HIS A CB 1 ATOM 5739 C CG . HIS A 1 720 ? 8.251 77.313 -0.574 1.00 38.04 ? 720 HIS A CG 1 ATOM 5740 N ND1 . HIS A 1 720 ? 8.103 75.983 -0.910 1.00 37.95 ? 720 HIS A ND1 1 ATOM 5741 C CD2 . HIS A 1 720 ? 7.692 78.027 -1.583 1.00 38.64 ? 720 HIS A CD2 1 ATOM 5742 C CE1 . HIS A 1 720 ? 7.491 75.897 -2.081 1.00 38.21 ? 720 HIS A CE1 1 ATOM 5743 N NE2 . HIS A 1 720 ? 7.233 77.122 -2.511 1.00 38.91 ? 720 HIS A NE2 1 ATOM 5744 N N . GLY A 1 721 ? 11.157 75.611 1.816 1.00 29.85 ? 721 GLY A N 1 ATOM 5745 C CA . GLY A 1 721 ? 11.634 74.246 1.958 1.00 27.92 ? 721 GLY A CA 1 ATOM 5746 C C . GLY A 1 721 ? 13.164 74.257 1.917 1.00 26.24 ? 721 GLY A C 1 ATOM 5747 O O . GLY A 1 721 ? 13.790 75.315 1.982 1.00 23.54 ? 721 GLY A O 1 ATOM 5748 N N . ASP A 1 722 ? 13.753 73.076 1.733 1.00 22.36 ? 722 ASP A N 1 ATOM 5749 C CA . ASP A 1 722 ? 15.207 72.928 1.779 1.00 17.87 ? 722 ASP A CA 1 ATOM 5750 C C . ASP A 1 722 ? 15.924 73.626 0.609 1.00 14.06 ? 722 ASP A C 1 ATOM 5751 O O . ASP A 1 722 ? 15.549 73.536 -0.540 1.00 15.22 ? 722 ASP A O 1 ATOM 5752 C CB . ASP A 1 722 ? 15.550 71.452 1.808 1.00 15.55 ? 722 ASP A CB 1 ATOM 5753 C CG . ASP A 1 722 ? 15.000 70.723 3.059 1.00 18.75 ? 722 ASP A CG 1 ATOM 5754 O OD1 . ASP A 1 722 ? 14.760 71.349 4.142 1.00 19.84 ? 722 ASP A OD1 1 ATOM 5755 O OD2 . ASP A 1 722 ? 14.825 69.489 2.965 1.00 16.77 ? 722 ASP A OD2 1 ATOM 5756 N N . ARG A 1 723 ? 17.001 74.321 0.975 1.00 13.20 ? 723 ARG A N 1 ATOM 5757 C CA . ARG A 1 723 ? 17.833 75.069 0.039 1.00 12.54 ? 723 ARG A CA 1 ATOM 5758 C C . ARG A 1 723 ? 19.104 74.317 -0.353 1.00 13.04 ? 723 ARG A C 1 ATOM 5759 O O . ARG A 1 723 ? 19.736 73.650 0.461 1.00 13.13 ? 723 ARG A O 1 ATOM 5760 C CB . ARG A 1 723 ? 18.196 76.437 0.610 1.00 14.82 ? 723 ARG A CB 1 ATOM 5761 C CG . ARG A 1 723 ? 16.993 77.358 0.825 1.00 27.65 ? 723 ARG A CG 1 ATOM 5762 C CD . ARG A 1 723 ? 17.393 78.650 1.507 1.00 37.70 ? 723 ARG A CD 1 ATOM 5763 N NE . ARG A 1 723 ? 16.248 79.523 1.713 1.00 40.06 ? 723 ARG A NE 1 ATOM 5764 C CZ . ARG A 1 723 ? 16.332 80.743 2.219 1.00 42.28 ? 723 ARG A CZ 1 ATOM 5765 N NH1 . ARG A 1 723 ? 15.236 81.471 2.366 1.00 41.50 ? 723 ARG A NH1 1 ATOM 5766 N NH2 . ARG A 1 723 ? 17.512 81.238 2.582 1.00 42.10 ? 723 ARG A NH2 1 ATOM 5767 N N . SER A 1 724 ? 19.459 74.447 -1.623 1.00 10.44 ? 724 SER A N 1 ATOM 5768 C CA . SER A 1 724 ? 20.723 73.958 -2.142 1.00 9.45 ? 724 SER A CA 1 ATOM 5769 C C . SER A 1 724 ? 21.836 74.650 -1.362 1.00 9.96 ? 724 SER A C 1 ATOM 5770 O O . SER A 1 724 ? 21.750 75.855 -1.015 1.00 12.41 ? 724 SER A O 1 ATOM 5771 C CB . SER A 1 724 ? 20.888 74.335 -3.627 1.00 10.02 ? 724 SER A CB 1 ATOM 5772 O OG . SER A 1 724 ? 19.877 73.691 -4.355 1.00 10.57 ? 724 SER A OG 1 ATOM 5773 N N . GLY A 1 725 ? 22.959 73.933 -1.187 1.00 9.06 ? 725 GLY A N 1 ATOM 5774 C CA . GLY A 1 725 ? 24.148 74.478 -0.526 1.00 8.31 ? 725 GLY A CA 1 ATOM 5775 C C . GLY A 1 725 ? 25.381 73.738 -1.072 1.00 8.03 ? 725 GLY A C 1 ATOM 5776 O O . GLY A 1 725 ? 25.290 73.108 -2.161 1.00 8.58 ? 725 GLY A O 1 ATOM 5777 N N . ALA A 1 726 ? 26.510 73.813 -0.367 1.00 8.19 ? 726 ALA A N 1 ATOM 5778 C CA . ALA A 1 726 ? 27.697 73.144 -0.856 1.00 6.88 ? 726 ALA A CA 1 ATOM 5779 C C . ALA A 1 726 ? 27.529 71.650 -1.107 1.00 7.78 ? 726 ALA A C 1 ATOM 5780 O O . ALA A 1 726 ? 28.225 71.085 -1.988 1.00 7.74 ? 726 ALA A O 1 ATOM 5781 C CB . ALA A 1 726 ? 28.892 73.346 0.119 1.00 8.16 ? 726 ALA A CB 1 ATOM 5782 N N . TYR A 1 727 ? 26.712 70.973 -0.298 1.00 7.05 ? 727 TYR A N 1 ATOM 5783 C CA . TYR A 1 727 ? 26.486 69.533 -0.444 1.00 7.05 ? 727 TYR A CA 1 ATOM 5784 C C . TYR A 1 727 ? 25.329 69.166 -1.341 1.00 6.96 ? 727 TYR A C 1 ATOM 5785 O O . TYR A 1 727 ? 25.434 68.319 -2.220 1.00 8.26 ? 727 TYR A O 1 ATOM 5786 C CB . TYR A 1 727 ? 26.206 68.897 0.926 1.00 7.23 ? 727 TYR A CB 1 ATOM 5787 C CG . TYR A 1 727 ? 27.262 69.204 1.989 1.00 7.40 ? 727 TYR A CG 1 ATOM 5788 C CD1 . TYR A 1 727 ? 27.142 70.344 2.775 1.00 7.96 ? 727 TYR A CD1 1 ATOM 5789 C CD2 . TYR A 1 727 ? 28.368 68.358 2.194 1.00 7.67 ? 727 TYR A CD2 1 ATOM 5790 C CE1 . TYR A 1 727 ? 28.108 70.642 3.759 1.00 8.21 ? 727 TYR A CE1 1 ATOM 5791 C CE2 . TYR A 1 727 ? 29.323 68.649 3.166 1.00 6.52 ? 727 TYR A CE2 1 ATOM 5792 C CZ . TYR A 1 727 ? 29.171 69.782 3.932 1.00 6.76 ? 727 TYR A CZ 1 ATOM 5793 O OH . TYR A 1 727 ? 30.056 70.051 4.980 1.00 7.61 ? 727 TYR A OH 1 ATOM 5794 N N . LEU A 1 728 ? 24.191 69.829 -1.088 1.00 7.44 ? 728 LEU A N 1 ATOM 5795 C CA . LEU A 1 728 ? 22.923 69.439 -1.706 1.00 8.10 ? 728 LEU A CA 1 ATOM 5796 C C . LEU A 1 728 ? 22.563 70.208 -2.943 1.00 7.27 ? 728 LEU A C 1 ATOM 5797 O O . LEU A 1 728 ? 22.738 71.405 -2.987 1.00 8.58 ? 728 LEU A O 1 ATOM 5798 C CB . LEU A 1 728 ? 21.734 69.642 -0.702 1.00 9.50 ? 728 LEU A CB 1 ATOM 5799 C CG . LEU A 1 728 ? 21.912 69.002 0.698 1.00 7.72 ? 728 LEU A CG 1 ATOM 5800 C CD1 . LEU A 1 728 ? 20.623 69.283 1.501 1.00 11.88 ? 728 LEU A CD1 1 ATOM 5801 C CD2 . LEU A 1 728 ? 22.235 67.534 0.627 1.00 9.45 ? 728 LEU A CD2 1 ATOM 5802 N N . PHE A 1 729 ? 22.022 69.478 -3.923 1.00 7.49 ? 729 PHE A N 1 ATOM 5803 C CA . PHE A 1 729 ? 21.479 70.084 -5.146 1.00 7.82 ? 729 PHE A CA 1 ATOM 5804 C C . PHE A 1 729 ? 19.949 69.866 -5.043 1.00 8.51 ? 729 PHE A C 1 ATOM 5805 O O . PHE A 1 729 ? 19.465 68.729 -5.154 1.00 8.79 ? 729 PHE A O 1 ATOM 5806 C CB . PHE A 1 729 ? 22.086 69.353 -6.346 1.00 8.47 ? 729 PHE A CB 1 ATOM 5807 C CG . PHE A 1 729 ? 21.537 69.784 -7.694 1.00 7.58 ? 729 PHE A CG 1 ATOM 5808 C CD1 . PHE A 1 729 ? 21.223 71.120 -7.944 1.00 9.04 ? 729 PHE A CD1 1 ATOM 5809 C CD2 . PHE A 1 729 ? 21.447 68.863 -8.721 1.00 7.43 ? 729 PHE A CD2 1 ATOM 5810 C CE1 . PHE A 1 729 ? 20.815 71.534 -9.249 1.00 7.89 ? 729 PHE A CE1 1 ATOM 5811 C CE2 . PHE A 1 729 ? 21.043 69.269 -10.021 1.00 9.22 ? 729 PHE A CE2 1 ATOM 5812 C CZ . PHE A 1 729 ? 20.728 70.603 -10.280 1.00 8.64 ? 729 PHE A CZ 1 ATOM 5813 N N . LEU A 1 730 ? 19.242 70.986 -4.863 1.00 9.12 ? 730 LEU A N 1 ATOM 5814 C CA . LEU A 1 730 ? 17.757 70.978 -4.669 1.00 9.78 ? 730 LEU A CA 1 ATOM 5815 C C . LEU A 1 730 ? 17.170 72.000 -5.642 1.00 9.58 ? 730 LEU A C 1 ATOM 5816 O O . LEU A 1 730 ? 16.743 73.089 -5.255 1.00 9.78 ? 730 LEU A O 1 ATOM 5817 C CB . LEU A 1 730 ? 17.438 71.336 -3.190 1.00 10.65 ? 730 LEU A CB 1 ATOM 5818 C CG . LEU A 1 730 ? 17.827 70.204 -2.210 1.00 10.96 ? 730 LEU A CG 1 ATOM 5819 C CD1 . LEU A 1 730 ? 17.862 70.748 -0.808 1.00 11.19 ? 730 LEU A CD1 1 ATOM 5820 C CD2 . LEU A 1 730 ? 16.832 69.050 -2.311 1.00 14.04 ? 730 LEU A CD2 1 ATOM 5821 N N . PRO A 1 731 ? 17.209 71.686 -6.930 1.00 10.10 ? 731 PRO A N 1 ATOM 5822 C CA . PRO A 1 731 ? 16.714 72.632 -7.933 1.00 10.11 ? 731 PRO A CA 1 ATOM 5823 C C . PRO A 1 731 ? 15.254 72.926 -7.830 1.00 10.03 ? 731 PRO A C 1 ATOM 5824 O O . PRO A 1 731 ? 14.459 72.092 -7.376 1.00 11.46 ? 731 PRO A O 1 ATOM 5825 C CB . PRO A 1 731 ? 17.073 71.941 -9.232 1.00 11.12 ? 731 PRO A CB 1 ATOM 5826 C CG . PRO A 1 731 ? 16.991 70.465 -8.941 1.00 9.88 ? 731 PRO A CG 1 ATOM 5827 C CD . PRO A 1 731 ? 17.609 70.396 -7.536 1.00 8.59 ? 731 PRO A CD 1 ATOM 5828 N N . ASN A 1 732 ? 14.938 74.137 -8.298 1.00 11.63 ? 732 ASN A N 1 ATOM 5829 C CA . ASN A 1 732 ? 13.505 74.541 -8.357 1.00 12.19 ? 732 ASN A CA 1 ATOM 5830 C C . ASN A 1 732 ? 13.012 74.144 -9.744 1.00 13.04 ? 732 ASN A C 1 ATOM 5831 O O . ASN A 1 732 ? 12.611 75.019 -10.542 1.00 18.52 ? 732 ASN A O 1 ATOM 5832 C CB . ASN A 1 732 ? 13.357 76.059 -8.102 1.00 14.51 ? 732 ASN A CB 1 ATOM 5833 C CG . ASN A 1 732 ? 14.103 76.922 -9.106 1.00 20.62 ? 732 ASN A CG 1 ATOM 5834 O OD1 . ASN A 1 732 ? 15.060 76.517 -9.714 1.00 18.84 ? 732 ASN A OD1 1 ATOM 5835 N ND2 . ASN A 1 732 ? 13.638 78.173 -9.261 1.00 22.61 ? 732 ASN A ND2 1 ATOM 5836 N N . GLY A 1 733 ? 13.114 72.886 -10.101 1.00 11.34 ? 733 GLY A N 1 ATOM 5837 C CA . GLY A 1 733 ? 12.658 72.404 -11.401 1.00 12.87 ? 733 GLY A CA 1 ATOM 5838 C C . GLY A 1 733 ? 13.754 72.340 -12.474 1.00 10.45 ? 733 GLY A C 1 ATOM 5839 O O . GLY A 1 733 ? 14.923 72.721 -12.213 1.00 10.78 ? 733 GLY A O 1 ATOM 5840 N N . PRO A 1 734 ? 13.419 71.849 -13.670 1.00 9.47 ? 734 PRO A N 1 ATOM 5841 C CA . PRO A 1 734 ? 14.371 71.756 -14.778 1.00 10.28 ? 734 PRO A CA 1 ATOM 5842 C C . PRO A 1 734 ? 14.987 73.134 -15.077 1.00 10.10 ? 734 PRO A C 1 ATOM 5843 O O . PRO A 1 734 ? 14.425 74.194 -14.827 1.00 10.47 ? 734 PRO A O 1 ATOM 5844 C CB . PRO A 1 734 ? 13.532 71.284 -15.954 1.00 11.33 ? 734 PRO A CB 1 ATOM 5845 C CG . PRO A 1 734 ? 12.452 70.420 -15.265 1.00 16.90 ? 734 PRO A CG 1 ATOM 5846 C CD . PRO A 1 734 ? 12.110 71.264 -14.039 1.00 12.19 ? 734 PRO A CD 1 ATOM 5847 N N . ALA A 1 735 ? 16.189 73.076 -15.642 1.00 9.30 ? 735 ALA A N 1 ATOM 5848 C CA . ALA A 1 735 ? 16.914 74.298 -15.981 1.00 9.17 ? 735 ALA A CA 1 ATOM 5849 C C . ALA A 1 735 ? 16.245 75.134 -17.072 1.00 9.22 ? 735 ALA A C 1 ATOM 5850 O O . ALA A 1 735 ? 15.558 74.588 -17.925 1.00 11.66 ? 735 ALA A O 1 ATOM 5851 C CB . ALA A 1 735 ? 18.308 73.873 -16.392 1.00 10.01 ? 735 ALA A CB 1 ATOM 5852 N N . SER A 1 736 ? 16.494 76.438 -17.001 1.00 10.53 ? 736 SER A N 1 ATOM 5853 C CA . SER A 1 736 ? 15.957 77.402 -17.978 1.00 11.24 ? 736 SER A CA 1 ATOM 5854 C C . SER A 1 736 ? 17.117 77.894 -18.830 1.00 11.63 ? 736 SER A C 1 ATOM 5855 O O . SER A 1 736 ? 18.190 78.140 -18.312 1.00 11.22 ? 736 SER A O 1 ATOM 5856 C CB . SER A 1 736 ? 15.365 78.570 -17.233 1.00 14.31 ? 736 SER A CB 1 ATOM 5857 O OG . SER A 1 736 ? 14.444 78.121 -16.258 1.00 26.24 ? 736 SER A OG 1 ATOM 5858 N N . PRO A 1 737 ? 16.910 78.108 -20.127 1.00 13.37 ? 737 PRO A N 1 ATOM 5859 C CA . PRO A 1 737 ? 18.026 78.568 -20.976 1.00 14.80 ? 737 PRO A CA 1 ATOM 5860 C C . PRO A 1 737 ? 18.585 79.909 -20.519 1.00 14.80 ? 737 PRO A C 1 ATOM 5861 O O . PRO A 1 737 ? 17.832 80.822 -20.105 1.00 16.16 ? 737 PRO A O 1 ATOM 5862 C CB . PRO A 1 737 ? 17.396 78.730 -22.378 1.00 18.39 ? 737 PRO A CB 1 ATOM 5863 C CG . PRO A 1 737 ? 16.206 77.814 -22.330 1.00 20.01 ? 737 PRO A CG 1 ATOM 5864 C CD . PRO A 1 737 ? 15.665 77.960 -20.903 1.00 15.45 ? 737 PRO A CD 1 ATOM 5865 N N . VAL A 1 738 ? 19.915 80.060 -20.573 1.00 13.77 ? 738 VAL A N 1 ATOM 5866 C CA . VAL A 1 738 ? 20.528 81.372 -20.311 1.00 11.12 ? 738 VAL A CA 1 ATOM 5867 C C . VAL A 1 738 ? 20.124 82.259 -21.539 1.00 12.12 ? 738 VAL A C 1 ATOM 5868 O O . VAL A 1 738 ? 20.222 81.836 -22.689 1.00 14.78 ? 738 VAL A O 1 ATOM 5869 C CB . VAL A 1 738 ? 22.075 81.230 -20.241 1.00 12.85 ? 738 VAL A CB 1 ATOM 5870 C CG1 . VAL A 1 738 ? 22.733 82.646 -20.212 1.00 16.45 ? 738 VAL A CG1 1 ATOM 5871 C CG2 . VAL A 1 738 ? 22.526 80.434 -18.964 1.00 14.82 ? 738 VAL A CG2 1 ATOM 5872 N N . GLU A 1 739 ? 19.667 83.474 -21.262 1.00 14.63 ? 739 GLU A N 1 ATOM 5873 C CA . GLU A 1 739 ? 19.272 84.427 -22.320 1.00 16.61 ? 739 GLU A CA 1 ATOM 5874 C C . GLU A 1 739 ? 20.610 84.953 -22.872 1.00 13.93 ? 739 GLU A C 1 ATOM 5875 O O . GLU A 1 739 ? 21.376 85.576 -22.139 1.00 16.49 ? 739 GLU A O 1 ATOM 5876 C CB . GLU A 1 739 ? 18.495 85.573 -21.689 1.00 20.71 ? 739 GLU A CB 1 ATOM 5877 C CG . GLU A 1 739 ? 17.157 85.164 -21.195 1.00 31.74 ? 739 GLU A CG 1 ATOM 5878 C CD . GLU A 1 739 ? 16.223 86.359 -20.938 1.00 40.12 ? 739 GLU A CD 1 ATOM 5879 O OE1 . GLU A 1 739 ? 16.555 87.497 -21.330 1.00 39.86 ? 739 GLU A OE1 1 ATOM 5880 O OE2 . GLU A 1 739 ? 15.147 86.135 -20.346 1.00 44.78 ? 739 GLU A OE2 1 ATOM 5881 N N . LEU A 1 740 ? 20.855 84.704 -24.146 1.00 16.55 ? 740 LEU A N 1 ATOM 5882 C CA . LEU A 1 740 ? 22.168 85.021 -24.730 1.00 17.03 ? 740 LEU A CA 1 ATOM 5883 C C . LEU A 1 740 ? 22.355 86.407 -25.318 1.00 19.80 ? 740 LEU A C 1 ATOM 5884 O O . LEU A 1 740 ? 23.483 86.853 -25.484 1.00 21.82 ? 740 LEU A O 1 ATOM 5885 C CB . LEU A 1 740 ? 22.495 84.000 -25.820 1.00 18.98 ? 740 LEU A CB 1 ATOM 5886 C CG . LEU A 1 740 ? 22.521 82.537 -25.345 1.00 14.78 ? 740 LEU A CG 1 ATOM 5887 C CD1 . LEU A 1 740 ? 22.993 81.642 -26.465 1.00 16.49 ? 740 LEU A CD1 1 ATOM 5888 C CD2 . LEU A 1 740 ? 23.499 82.377 -24.117 1.00 18.14 ? 740 LEU A CD2 1 ATOM 5889 N N . GLY A 1 741 ? 21.255 87.068 -25.632 1.00 21.12 ? 741 GLY A N 1 ATOM 5890 C CA . GLY A 1 741 ? 21.379 88.372 -26.289 1.00 19.57 ? 741 GLY A CA 1 ATOM 5891 C C . GLY A 1 741 ? 21.939 88.170 -27.713 1.00 20.01 ? 741 GLY A C 1 ATOM 5892 O O . GLY A 1 741 ? 21.587 87.213 -28.374 1.00 21.82 ? 741 GLY A O 1 ATOM 5893 N N . GLN A 1 742 ? 22.735 89.108 -28.212 1.00 21.15 ? 742 GLN A N 1 ATOM 5894 C CA . GLN A 1 742 ? 23.412 88.888 -29.482 1.00 17.81 ? 742 GLN A CA 1 ATOM 5895 C C . GLN A 1 742 ? 24.907 88.862 -29.178 1.00 17.74 ? 742 GLN A C 1 ATOM 5896 O O . GLN A 1 742 ? 25.569 89.884 -29.229 1.00 18.45 ? 742 GLN A O 1 ATOM 5897 C CB . GLN A 1 742 ? 23.114 89.997 -30.513 1.00 23.57 ? 742 GLN A CB 1 ATOM 5898 C CG . GLN A 1 742 ? 23.336 89.577 -31.965 1.00 31.46 ? 742 GLN A CG 1 ATOM 5899 C CD . GLN A 1 742 ? 22.603 90.450 -32.990 1.00 40.05 ? 742 GLN A CD 1 ATOM 5900 O OE1 . GLN A 1 742 ? 22.891 90.381 -34.177 1.00 40.30 ? 742 GLN A OE1 1 ATOM 5901 N NE2 . GLN A 1 742 ? 21.635 91.248 -32.530 1.00 39.36 ? 742 GLN A NE2 1 ATOM 5902 N N . PRO A 1 743 ? 25.416 87.696 -28.802 1.00 15.09 ? 743 PRO A N 1 ATOM 5903 C CA . PRO A 1 743 ? 26.831 87.656 -28.414 1.00 11.57 ? 743 PRO A CA 1 ATOM 5904 C C . PRO A 1 743 ? 27.892 87.838 -29.501 1.00 12.20 ? 743 PRO A C 1 ATOM 5905 O O . PRO A 1 743 ? 27.662 87.602 -30.678 1.00 13.92 ? 743 PRO A O 1 ATOM 5906 C CB . PRO A 1 743 ? 26.940 86.315 -27.674 1.00 14.69 ? 743 PRO A CB 1 ATOM 5907 C CG . PRO A 1 743 ? 25.957 85.432 -28.397 1.00 13.85 ? 743 PRO A CG 1 ATOM 5908 C CD . PRO A 1 743 ? 24.787 86.359 -28.777 1.00 12.80 ? 743 PRO A CD 1 ATOM 5909 N N . VAL A 1 744 ? 29.047 88.335 -29.067 1.00 10.44 ? 744 VAL A N 1 ATOM 5910 C CA . VAL A 1 744 ? 30.186 88.532 -29.988 1.00 10.06 ? 744 VAL A CA 1 ATOM 5911 C C . VAL A 1 744 ? 30.866 87.188 -30.211 1.00 8.31 ? 744 VAL A C 1 ATOM 5912 O O . VAL A 1 744 ? 31.204 86.470 -29.239 1.00 9.81 ? 744 VAL A O 1 ATOM 5913 C CB . VAL A 1 744 ? 31.185 89.519 -29.360 1.00 9.55 ? 744 VAL A CB 1 ATOM 5914 C CG1 . VAL A 1 744 ? 32.380 89.705 -30.285 1.00 11.55 ? 744 VAL A CG1 1 ATOM 5915 C CG2 . VAL A 1 744 ? 30.488 90.941 -29.156 1.00 12.62 ? 744 VAL A CG2 1 ATOM 5916 N N . VAL A 1 745 ? 31.066 86.825 -31.446 1.00 7.67 ? 745 VAL A N 1 ATOM 5917 C CA . VAL A 1 745 ? 31.681 85.539 -31.851 1.00 8.09 ? 745 VAL A CA 1 ATOM 5918 C C . VAL A 1 745 ? 32.981 85.765 -32.568 1.00 7.91 ? 745 VAL A C 1 ATOM 5919 O O . VAL A 1 745 ? 33.054 86.595 -33.509 1.00 9.78 ? 745 VAL A O 1 ATOM 5920 C CB . VAL A 1 745 ? 30.711 84.749 -32.763 1.00 8.65 ? 745 VAL A CB 1 ATOM 5921 C CG1 . VAL A 1 745 ? 31.367 83.413 -33.197 1.00 10.38 ? 745 VAL A CG1 1 ATOM 5922 C CG2 . VAL A 1 745 ? 29.401 84.522 -32.031 1.00 9.13 ? 745 VAL A CG2 1 ATOM 5923 N N . LEU A 1 746 ? 34.086 85.126 -32.171 1.00 7.75 ? 746 LEU A N 1 ATOM 5924 C CA . LEU A 1 746 ? 35.372 85.271 -32.803 1.00 7.84 ? 746 LEU A CA 1 ATOM 5925 C C . LEU A 1 746 ? 35.781 83.987 -33.455 1.00 8.37 ? 746 LEU A C 1 ATOM 5926 O O . LEU A 1 746 ? 35.831 82.927 -32.780 1.00 8.41 ? 746 LEU A O 1 ATOM 5927 C CB . LEU A 1 746 ? 36.400 85.654 -31.723 1.00 9.47 ? 746 LEU A CB 1 ATOM 5928 C CG . LEU A 1 746 ? 37.852 85.615 -32.225 1.00 11.53 ? 746 LEU A CG 1 ATOM 5929 C CD1 . LEU A 1 746 ? 38.160 86.729 -33.278 1.00 14.00 ? 746 LEU A CD1 1 ATOM 5930 C CD2 . LEU A 1 746 ? 38.759 85.773 -30.950 1.00 15.15 ? 746 LEU A CD2 1 ATOM 5931 N N . VAL A 1 747 ? 36.046 84.009 -34.731 1.00 7.81 ? 747 VAL A N 1 ATOM 5932 C CA . VAL A 1 747 ? 36.450 82.820 -35.486 1.00 7.93 ? 747 VAL A CA 1 ATOM 5933 C C . VAL A 1 747 ? 37.883 82.950 -35.919 1.00 9.48 ? 747 VAL A C 1 ATOM 5934 O O . VAL A 1 747 ? 38.265 83.924 -36.596 1.00 10.40 ? 747 VAL A O 1 ATOM 5935 C CB . VAL A 1 747 ? 35.559 82.667 -36.747 1.00 10.04 ? 747 VAL A CB 1 ATOM 5936 C CG1 . VAL A 1 747 ? 35.923 81.347 -37.502 1.00 11.25 ? 747 VAL A CG1 1 ATOM 5937 C CG2 . VAL A 1 747 ? 34.113 82.706 -36.371 1.00 10.32 ? 747 VAL A CG2 1 ATOM 5938 N N . THR A 1 748 ? 38.747 82.014 -35.557 1.00 8.70 ? 748 THR A N 1 ATOM 5939 C CA . THR A 1 748 ? 40.117 82.014 -35.999 1.00 9.83 ? 748 THR A CA 1 ATOM 5940 C C . THR A 1 748 ? 40.316 80.806 -36.857 1.00 9.65 ? 748 THR A C 1 ATOM 5941 O O . THR A 1 748 ? 39.994 79.674 -36.433 1.00 12.09 ? 748 THR A O 1 ATOM 5942 C CB . THR A 1 748 ? 41.058 82.033 -34.767 1.00 11.44 ? 748 THR A CB 1 ATOM 5943 O OG1 . THR A 1 748 ? 40.828 83.250 -34.006 1.00 13.13 ? 748 THR A OG1 1 ATOM 5944 C CG2 . THR A 1 748 ? 42.497 81.945 -35.195 1.00 12.65 ? 748 THR A CG2 1 ATOM 5945 N N . LYS A 1 749 ? 40.804 80.965 -38.086 1.00 9.28 ? 749 LYS A N 1 ATOM 5946 C CA . LYS A 1 749 ? 40.967 79.847 -39.009 1.00 9.63 ? 749 LYS A CA 1 ATOM 5947 C C . LYS A 1 749 ? 42.412 79.709 -39.387 1.00 10.87 ? 749 LYS A C 1 ATOM 5948 O O . LYS A 1 749 ? 43.044 80.646 -39.946 1.00 10.55 ? 749 LYS A O 1 ATOM 5949 C CB . LYS A 1 749 ? 40.145 80.047 -40.286 1.00 12.42 ? 749 LYS A CB 1 ATOM 5950 C CG . LYS A 1 749 ? 40.335 78.879 -41.298 1.00 14.63 ? 749 LYS A CG 1 ATOM 5951 C CD . LYS A 1 749 ? 39.399 79.100 -42.540 1.00 17.67 ? 749 LYS A CD 1 ATOM 5952 C CE . LYS A 1 749 ? 39.762 78.264 -43.733 1.00 24.26 ? 749 LYS A CE 1 ATOM 5953 N NZ . LYS A 1 749 ? 38.879 78.835 -44.817 1.00 33.26 ? 749 LYS A NZ 1 ATOM 5954 N N . GLY A 1 750 ? 42.986 78.554 -39.069 1.00 10.10 ? 750 GLY A N 1 ATOM 5955 C CA . GLY A 1 750 ? 44.368 78.287 -39.387 1.00 11.14 ? 750 GLY A CA 1 ATOM 5956 C C . GLY A 1 750 ? 44.563 76.899 -39.964 1.00 11.09 ? 750 GLY A C 1 ATOM 5957 O O . GLY A 1 750 ? 43.679 76.022 -39.880 1.00 12.54 ? 750 GLY A O 1 ATOM 5958 N N . LYS A 1 751 ? 45.747 76.702 -40.545 1.00 11.88 ? 751 LYS A N 1 ATOM 5959 C CA . LYS A 1 751 ? 46.067 75.415 -41.133 1.00 11.88 ? 751 LYS A CA 1 ATOM 5960 C C . LYS A 1 751 ? 46.199 74.325 -40.047 1.00 10.90 ? 751 LYS A C 1 ATOM 5961 O O . LYS A 1 751 ? 45.807 73.169 -40.287 1.00 12.07 ? 751 LYS A O 1 ATOM 5962 C CB . LYS A 1 751 ? 47.374 75.491 -41.901 1.00 15.43 ? 751 LYS A CB 1 ATOM 5963 C CG . LYS A 1 751 ? 47.685 74.165 -42.617 1.00 24.91 ? 751 LYS A CG 1 ATOM 5964 C CD . LYS A 1 751 ? 48.709 74.335 -43.751 1.00 32.07 ? 751 LYS A CD 1 ATOM 5965 C CE . LYS A 1 751 ? 48.908 72.985 -44.436 1.00 34.98 ? 751 LYS A CE 1 ATOM 5966 N NZ . LYS A 1 751 ? 47.583 72.344 -44.790 1.00 42.34 ? 751 LYS A NZ 1 ATOM 5967 N N . LEU A 1 752 ? 46.772 74.670 -38.896 1.00 9.75 ? 752 LEU A N 1 ATOM 5968 C CA . LEU A 1 752 ? 46.971 73.670 -37.814 1.00 9.57 ? 752 LEU A CA 1 ATOM 5969 C C . LEU A 1 752 ? 45.890 73.709 -36.745 1.00 10.83 ? 752 LEU A C 1 ATOM 5970 O O . LEU A 1 752 ? 45.579 72.696 -36.133 1.00 10.07 ? 752 LEU A O 1 ATOM 5971 C CB . LEU A 1 752 ? 48.318 73.892 -37.132 1.00 10.04 ? 752 LEU A CB 1 ATOM 5972 C CG . LEU A 1 752 ? 49.549 73.820 -38.059 1.00 11.66 ? 752 LEU A CG 1 ATOM 5973 C CD1 . LEU A 1 752 ? 50.815 73.921 -37.209 1.00 13.31 ? 752 LEU A CD1 1 ATOM 5974 C CD2 . LEU A 1 752 ? 49.503 72.632 -38.982 1.00 16.08 ? 752 LEU A CD2 1 ATOM 5975 N N . GLU A 1 753 ? 45.288 74.873 -36.507 1.00 10.50 ? 753 GLU A N 1 ATOM 5976 C CA . GLU A 1 753 ? 44.313 75.014 -35.437 1.00 9.44 ? 753 GLU A CA 1 ATOM 5977 C C . GLU A 1 753 ? 43.323 76.102 -35.806 1.00 9.36 ? 753 GLU A C 1 ATOM 5978 O O . GLU A 1 753 ? 43.736 77.212 -36.235 1.00 10.08 ? 753 GLU A O 1 ATOM 5979 C CB . GLU A 1 753 ? 45.038 75.384 -34.133 1.00 9.43 ? 753 GLU A CB 1 ATOM 5980 C CG . GLU A 1 753 ? 44.087 75.595 -32.914 1.00 12.67 ? 753 GLU A CG 1 ATOM 5981 C CD . GLU A 1 753 ? 44.829 76.016 -31.641 1.00 17.57 ? 753 GLU A CD 1 ATOM 5982 O OE1 . GLU A 1 753 ? 45.150 77.215 -31.532 1.00 22.80 ? 753 GLU A OE1 1 ATOM 5983 O OE2 . GLU A 1 753 ? 45.063 75.125 -30.807 1.00 21.13 ? 753 GLU A OE2 1 ATOM 5984 N N . SER A 1 754 ? 42.060 75.816 -35.591 1.00 8.80 ? 754 SER A N 1 ATOM 5985 C CA . SER A 1 754 ? 40.994 76.817 -35.808 1.00 8.15 ? 754 SER A CA 1 ATOM 5986 C C . SER A 1 754 ? 40.130 76.822 -34.567 1.00 8.74 ? 754 SER A C 1 ATOM 5987 O O . SER A 1 754 ? 40.132 75.864 -33.748 1.00 9.29 ? 754 SER A O 1 ATOM 5988 C CB . SER A 1 754 ? 40.167 76.458 -37.013 1.00 8.47 ? 754 SER A CB 1 ATOM 5989 O OG . SER A 1 754 ? 40.940 76.583 -38.208 1.00 9.17 ? 754 SER A OG 1 ATOM 5990 N N . SER A 1 755 ? 39.355 77.877 -34.363 1.00 7.94 ? 755 SER A N 1 ATOM 5991 C CA . SER A 1 755 ? 38.486 77.907 -33.197 1.00 9.67 ? 755 SER A CA 1 ATOM 5992 C C . SER A 1 755 ? 37.371 78.911 -33.338 1.00 8.39 ? 755 SER A C 1 ATOM 5993 O O . SER A 1 755 ? 37.491 79.886 -34.121 1.00 9.12 ? 755 SER A O 1 ATOM 5994 C CB A SER A 1 755 ? 39.282 78.270 -31.959 0.50 13.92 ? 755 SER A CB 1 ATOM 5995 C CB B SER A 1 755 ? 39.453 78.357 -32.036 0.50 16.75 ? 755 SER A CB 1 ATOM 5996 O OG A SER A 1 755 ? 39.793 79.584 -32.087 0.50 14.76 ? 755 SER A OG 1 ATOM 5997 O OG B SER A 1 755 ? 38.910 79.286 -31.123 0.50 37.39 ? 755 SER A OG 1 ATOM 5998 N N . VAL A 1 756 ? 36.295 78.691 -32.604 1.00 7.09 ? 756 VAL A N 1 ATOM 5999 C CA . VAL A 1 756 ? 35.144 79.590 -32.527 1.00 8.06 ? 756 VAL A CA 1 ATOM 6000 C C . VAL A 1 756 ? 34.996 79.902 -31.034 1.00 8.05 ? 756 VAL A C 1 ATOM 6001 O O . VAL A 1 756 ? 34.831 78.952 -30.208 1.00 9.50 ? 756 VAL A O 1 ATOM 6002 C CB . VAL A 1 756 ? 33.855 78.950 -33.054 1.00 8.10 ? 756 VAL A CB 1 ATOM 6003 C CG1 . VAL A 1 756 ? 32.651 79.920 -32.824 1.00 10.01 ? 756 VAL A CG1 1 ATOM 6004 C CG2 . VAL A 1 756 ? 34.084 78.615 -34.557 1.00 10.40 ? 756 VAL A CG2 1 ATOM 6005 N N . SER A 1 757 ? 35.007 81.170 -30.657 1.00 7.82 ? 757 SER A N 1 ATOM 6006 C CA . SER A 1 757 ? 34.861 81.556 -29.255 1.00 8.81 ? 757 SER A CA 1 ATOM 6007 C C . SER A 1 757 ? 33.733 82.538 -29.127 1.00 9.63 ? 757 SER A C 1 ATOM 6008 O O . SER A 1 757 ? 33.612 83.422 -30.013 1.00 11.02 ? 757 SER A O 1 ATOM 6009 C CB . SER A 1 757 ? 36.153 82.243 -28.759 1.00 10.56 ? 757 SER A CB 1 ATOM 6010 O OG . SER A 1 757 ? 37.288 81.387 -28.907 1.00 12.46 ? 757 SER A OG 1 ATOM 6011 N N . VAL A 1 758 ? 32.932 82.466 -28.079 1.00 7.84 ? 758 VAL A N 1 ATOM 6012 C CA . VAL A 1 758 ? 31.788 83.403 -27.930 1.00 7.45 ? 758 VAL A CA 1 ATOM 6013 C C . VAL A 1 758 ? 31.683 83.862 -26.507 1.00 7.82 ? 758 VAL A C 1 ATOM 6014 O O . VAL A 1 758 ? 31.845 83.041 -25.561 1.00 8.36 ? 758 VAL A O 1 ATOM 6015 C CB . VAL A 1 758 ? 30.474 82.754 -28.458 1.00 8.81 ? 758 VAL A CB 1 ATOM 6016 C CG1 . VAL A 1 758 ? 30.148 81.408 -27.731 1.00 10.16 ? 758 VAL A CG1 1 ATOM 6017 C CG2 . VAL A 1 758 ? 29.332 83.727 -28.272 1.00 9.49 ? 758 VAL A CG2 1 ATOM 6018 N N . GLY A 1 759 ? 31.419 85.140 -26.322 1.00 8.20 ? 759 GLY A N 1 ATOM 6019 C CA . GLY A 1 759 ? 31.276 85.702 -24.971 1.00 9.72 ? 759 GLY A CA 1 ATOM 6020 C C . GLY A 1 759 ? 29.856 85.670 -24.519 1.00 9.72 ? 759 GLY A C 1 ATOM 6021 O O . GLY A 1 759 ? 29.052 86.547 -24.846 1.00 10.66 ? 759 GLY A O 1 ATOM 6022 N N . LEU A 1 760 ? 29.462 84.646 -23.796 1.00 9.79 ? 760 LEU A N 1 ATOM 6023 C CA . LEU A 1 760 ? 28.119 84.502 -23.259 1.00 9.58 ? 760 LEU A CA 1 ATOM 6024 C C . LEU A 1 760 ? 28.062 85.002 -21.863 1.00 9.52 ? 760 LEU A C 1 ATOM 6025 O O . LEU A 1 760 ? 29.109 85.150 -21.212 1.00 11.12 ? 760 LEU A O 1 ATOM 6026 C CB . LEU A 1 760 ? 27.762 82.986 -23.246 1.00 11.50 ? 760 LEU A CB 1 ATOM 6027 C CG . LEU A 1 760 ? 27.925 82.290 -24.596 1.00 12.12 ? 760 LEU A CG 1 ATOM 6028 C CD1 . LEU A 1 760 ? 27.674 80.775 -24.473 1.00 14.42 ? 760 LEU A CD1 1 ATOM 6029 C CD2 . LEU A 1 760 ? 26.976 82.881 -25.633 1.00 14.82 ? 760 LEU A CD2 1 ATOM 6030 N N . PRO A 1 761 ? 26.879 85.244 -21.321 1.00 11.10 ? 761 PRO A N 1 ATOM 6031 C CA . PRO A 1 761 ? 26.815 85.697 -19.925 1.00 11.47 ? 761 PRO A CA 1 ATOM 6032 C C . PRO A 1 761 ? 27.375 84.553 -19.039 1.00 13.32 ? 761 PRO A C 1 ATOM 6033 O O . PRO A 1 761 ? 26.939 83.387 -19.133 1.00 14.02 ? 761 PRO A O 1 ATOM 6034 C CB . PRO A 1 761 ? 25.305 85.913 -19.681 1.00 13.80 ? 761 PRO A CB 1 ATOM 6035 C CG . PRO A 1 761 ? 24.754 86.161 -21.100 1.00 14.86 ? 761 PRO A CG 1 ATOM 6036 C CD . PRO A 1 761 ? 25.568 85.260 -21.989 1.00 12.88 ? 761 PRO A CD 1 ATOM 6037 N N . SER A 1 762 ? 28.345 84.924 -18.222 1.00 10.66 ? 762 SER A N 1 ATOM 6038 C CA . SER A 1 762 ? 29.085 84.062 -17.298 1.00 10.58 ? 762 SER A CA 1 ATOM 6039 C C . SER A 1 762 ? 30.026 83.066 -17.944 1.00 9.74 ? 762 SER A C 1 ATOM 6040 O O . SER A 1 762 ? 30.716 82.361 -17.191 1.00 9.89 ? 762 SER A O 1 ATOM 6041 C CB . SER A 1 762 ? 28.162 83.220 -16.401 1.00 13.13 ? 762 SER A CB 1 ATOM 6042 O OG . SER A 1 762 ? 27.197 83.993 -15.714 1.00 15.62 ? 762 SER A OG 1 ATOM 6043 N N . VAL A 1 763 ? 30.100 82.971 -19.260 1.00 8.92 ? 763 VAL A N 1 ATOM 6044 C CA . VAL A 1 763 ? 30.976 81.986 -19.847 1.00 8.74 ? 763 VAL A CA 1 ATOM 6045 C C . VAL A 1 763 ? 31.571 82.413 -21.182 1.00 8.95 ? 763 VAL A C 1 ATOM 6046 O O . VAL A 1 763 ? 30.805 82.745 -22.122 1.00 10.05 ? 763 VAL A O 1 ATOM 6047 C CB . VAL A 1 763 ? 30.231 80.640 -20.142 1.00 10.69 ? 763 VAL A CB 1 ATOM 6048 C CG1 . VAL A 1 763 ? 31.220 79.582 -20.699 1.00 10.52 ? 763 VAL A CG1 1 ATOM 6049 C CG2 . VAL A 1 763 ? 29.602 80.090 -18.900 1.00 14.78 ? 763 VAL A CG2 1 ATOM 6050 N N . VAL A 1 764 ? 32.886 82.390 -21.305 1.00 7.30 ? 764 VAL A N 1 ATOM 6051 C CA . VAL A 1 764 ? 33.479 82.523 -22.635 1.00 7.11 ? 764 VAL A CA 1 ATOM 6052 C C . VAL A 1 764 ? 33.662 81.071 -23.092 1.00 8.10 ? 764 VAL A C 1 ATOM 6053 O O . VAL A 1 764 ? 34.464 80.298 -22.499 1.00 7.28 ? 764 VAL A O 1 ATOM 6054 C CB . VAL A 1 764 ? 34.834 83.260 -22.665 1.00 7.90 ? 764 VAL A CB 1 ATOM 6055 C CG1 . VAL A 1 764 ? 35.372 83.329 -24.132 1.00 10.54 ? 764 VAL A CG1 1 ATOM 6056 C CG2 . VAL A 1 764 ? 34.617 84.695 -22.101 1.00 10.71 ? 764 VAL A CG2 1 ATOM 6057 N N . HIS A 1 765 ? 32.944 80.682 -24.124 1.00 7.19 ? 765 HIS A N 1 ATOM 6058 C CA . HIS A 1 765 ? 32.864 79.280 -24.557 1.00 6.91 ? 765 HIS A CA 1 ATOM 6059 C C . HIS A 1 765 ? 33.669 79.175 -25.842 1.00 7.65 ? 765 HIS A C 1 ATOM 6060 O O . HIS A 1 765 ? 33.498 79.980 -26.727 1.00 8.17 ? 765 HIS A O 1 ATOM 6061 C CB . HIS A 1 765 ? 31.383 78.921 -24.784 1.00 8.35 ? 765 HIS A CB 1 ATOM 6062 C CG . HIS A 1 765 ? 31.138 77.616 -25.479 1.00 7.22 ? 765 HIS A CG 1 ATOM 6063 N ND1 . HIS A 1 765 ? 31.321 76.385 -24.886 1.00 11.16 ? 765 HIS A ND1 1 ATOM 6064 C CD2 . HIS A 1 765 ? 30.656 77.365 -26.717 1.00 5.48 ? 765 HIS A CD2 1 ATOM 6065 C CE1 . HIS A 1 765 ? 30.986 75.434 -25.741 1.00 6.59 ? 765 HIS A CE1 1 ATOM 6066 N NE2 . HIS A 1 765 ? 30.579 76.002 -26.860 1.00 11.70 ? 765 HIS A NE2 1 ATOM 6067 N N . GLN A 1 766 ? 34.580 78.214 -25.911 1.00 7.60 ? 766 GLN A N 1 ATOM 6068 C CA . GLN A 1 766 ? 35.502 78.085 -27.024 1.00 7.72 ? 766 GLN A CA 1 ATOM 6069 C C . GLN A 1 766 ? 35.564 76.659 -27.555 1.00 8.02 ? 766 GLN A C 1 ATOM 6070 O O . GLN A 1 766 ? 35.739 75.701 -26.802 1.00 8.81 ? 766 GLN A O 1 ATOM 6071 C CB . GLN A 1 766 ? 36.908 78.489 -26.548 1.00 9.35 ? 766 GLN A CB 1 ATOM 6072 C CG A GLN A 1 766 ? 36.967 79.817 -25.768 0.50 19.37 ? 766 GLN A CG 1 ATOM 6073 C CG B GLN A 1 766 ? 37.861 78.306 -27.813 0.50 18.20 ? 766 GLN A CG 1 ATOM 6074 C CD A GLN A 1 766 ? 38.067 79.833 -24.671 0.50 29.04 ? 766 GLN A CD 1 ATOM 6075 C CD B GLN A 1 766 ? 39.274 78.725 -27.410 0.50 22.91 ? 766 GLN A CD 1 ATOM 6076 O OE1 A GLN A 1 766 ? 39.215 79.505 -24.960 0.50 26.71 ? 766 GLN A OE1 1 ATOM 6077 O OE1 B GLN A 1 766 ? 39.672 78.546 -26.267 0.50 27.14 ? 766 GLN A OE1 1 ATOM 6078 N NE2 A GLN A 1 766 ? 37.709 80.219 -23.411 0.50 19.72 ? 766 GLN A NE2 1 ATOM 6079 N NE2 B GLN A 1 766 ? 40.033 79.276 -28.360 0.50 26.40 ? 766 GLN A NE2 1 ATOM 6080 N N . THR A 1 767 ? 35.380 76.498 -28.862 1.00 6.65 ? 767 THR A N 1 ATOM 6081 C CA . THR A 1 767 ? 35.496 75.198 -29.525 1.00 7.23 ? 767 THR A CA 1 ATOM 6082 C C . THR A 1 767 ? 36.746 75.241 -30.375 1.00 7.58 ? 767 THR A C 1 ATOM 6083 O O . THR A 1 767 ? 36.848 76.122 -31.277 1.00 9.17 ? 767 THR A O 1 ATOM 6084 C CB . THR A 1 767 ? 34.286 74.898 -30.426 1.00 8.16 ? 767 THR A CB 1 ATOM 6085 O OG1 . THR A 1 767 ? 33.113 74.978 -29.638 1.00 10.96 ? 767 THR A OG1 1 ATOM 6086 C CG2 . THR A 1 767 ? 34.400 73.491 -31.037 1.00 9.20 ? 767 THR A CG2 1 ATOM 6087 N N . ILE A 1 768 ? 37.713 74.375 -30.126 1.00 7.88 ? 768 ILE A N 1 ATOM 6088 C CA . ILE A 1 768 ? 39.011 74.352 -30.796 1.00 7.93 ? 768 ILE A CA 1 ATOM 6089 C C . ILE A 1 768 ? 39.169 73.112 -31.613 1.00 9.57 ? 768 ILE A C 1 ATOM 6090 O O . ILE A 1 768 ? 38.871 72.003 -31.129 1.00 9.95 ? 768 ILE A O 1 ATOM 6091 C CB . ILE A 1 768 ? 40.134 74.436 -29.759 1.00 9.04 ? 768 ILE A CB 1 ATOM 6092 C CG1 . ILE A 1 768 ? 39.956 75.695 -28.937 1.00 11.05 ? 768 ILE A CG1 1 ATOM 6093 C CG2 . ILE A 1 768 ? 41.468 74.549 -30.482 1.00 11.88 ? 768 ILE A CG2 1 ATOM 6094 C CD1 . ILE A 1 768 ? 40.807 75.687 -27.567 1.00 14.91 ? 768 ILE A CD1 1 ATOM 6095 N N . MET A 1 769 ? 39.618 73.261 -32.853 1.00 8.88 ? 769 MET A N 1 ATOM 6096 C CA . MET A 1 769 ? 39.789 72.150 -33.803 1.00 8.43 ? 769 MET A CA 1 ATOM 6097 C C . MET A 1 769 ? 41.232 72.022 -34.225 1.00 9.67 ? 769 MET A C 1 ATOM 6098 O O . MET A 1 769 ? 41.843 72.994 -34.680 1.00 9.42 ? 769 MET A O 1 ATOM 6099 C CB . MET A 1 769 ? 38.974 72.426 -35.054 1.00 10.60 ? 769 MET A CB 1 ATOM 6100 C CG A MET A 1 769 ? 37.489 72.307 -34.821 0.50 11.54 ? 769 MET A CG 1 ATOM 6101 C CG B MET A 1 769 ? 37.472 72.690 -34.544 0.50 11.61 ? 769 MET A CG 1 ATOM 6102 S SD A MET A 1 769 ? 36.499 73.382 -35.934 0.50 15.15 ? 769 MET A SD 1 ATOM 6103 S SD B MET A 1 769 ? 36.398 73.005 -35.966 0.50 15.03 ? 769 MET A SD 1 ATOM 6104 C CE A MET A 1 769 ? 36.528 74.978 -35.024 0.50 25.62 ? 769 MET A CE 1 ATOM 6105 C CE B MET A 1 769 ? 36.830 71.676 -37.083 0.50 20.62 ? 769 MET A CE 1 ATOM 6106 N N . ARG A 1 770 ? 41.776 70.813 -34.138 1.00 9.77 ? 770 ARG A N 1 ATOM 6107 C CA . ARG A 1 770 ? 43.140 70.566 -34.536 1.00 10.23 ? 770 ARG A CA 1 ATOM 6108 C C . ARG A 1 770 ? 43.233 69.373 -35.462 1.00 11.33 ? 770 ARG A C 1 ATOM 6109 O O . ARG A 1 770 ? 44.330 68.888 -35.739 1.00 15.30 ? 770 ARG A O 1 ATOM 6110 C CB . ARG A 1 770 ? 44.034 70.344 -33.320 1.00 11.61 ? 770 ARG A CB 1 ATOM 6111 C CG . ARG A 1 770 ? 44.192 71.577 -32.476 1.00 13.66 ? 770 ARG A CG 1 ATOM 6112 C CD . ARG A 1 770 ? 44.952 71.282 -31.190 1.00 16.77 ? 770 ARG A CD 1 ATOM 6113 N NE A ARG A 1 770 ? 45.044 72.505 -30.418 0.50 22.09 ? 770 ARG A NE 1 ATOM 6114 N NE B ARG A 1 770 ? 44.908 72.414 -30.223 0.50 24.05 ? 770 ARG A NE 1 ATOM 6115 C CZ A ARG A 1 770 ? 45.563 72.594 -29.199 0.50 35.39 ? 770 ARG A CZ 1 ATOM 6116 C CZ B ARG A 1 770 ? 44.098 72.336 -29.168 0.50 32.65 ? 770 ARG A CZ 1 ATOM 6117 N NH1 A ARG A 1 770 ? 46.053 71.515 -28.601 0.50 37.63 ? 770 ARG A NH1 1 ATOM 6118 N NH1 B ARG A 1 770 ? 43.390 71.240 -28.960 0.50 36.15 ? 770 ARG A NH1 1 ATOM 6119 N NH2 A ARG A 1 770 ? 45.574 73.766 -28.572 0.50 37.82 ? 770 ARG A NH2 1 ATOM 6120 N NH2 B ARG A 1 770 ? 43.994 73.352 -28.322 0.50 39.95 ? 770 ARG A NH2 1 ATOM 6121 N N . GLY A 1 771 ? 42.103 68.901 -35.937 1.00 11.32 ? 771 GLY A N 1 ATOM 6122 C CA . GLY A 1 771 ? 42.161 67.783 -36.841 1.00 14.68 ? 771 GLY A CA 1 ATOM 6123 C C . GLY A 1 771 ? 41.491 66.548 -36.389 1.00 18.13 ? 771 GLY A C 1 ATOM 6124 O O . GLY A 1 771 ? 41.286 65.663 -37.237 1.00 19.32 ? 771 GLY A O 1 ATOM 6125 N N . GLY A 1 772 ? 41.163 66.475 -35.095 1.00 14.86 ? 772 GLY A N 1 ATOM 6126 C CA . GLY A 1 772 ? 40.443 65.310 -34.547 1.00 16.89 ? 772 GLY A CA 1 ATOM 6127 C C . GLY A 1 772 ? 39.234 65.813 -33.763 1.00 14.63 ? 772 GLY A C 1 ATOM 6128 O O . GLY A 1 772 ? 38.630 66.834 -34.100 1.00 13.12 ? 772 GLY A O 1 ATOM 6129 N N . ALA A 1 773 ? 38.849 65.097 -32.708 1.00 11.26 ? 773 ALA A N 1 ATOM 6130 C CA . ALA A 1 773 ? 37.730 65.545 -31.887 1.00 10.40 ? 773 ALA A CA 1 ATOM 6131 C C . ALA A 1 773 ? 38.034 66.929 -31.328 1.00 9.18 ? 773 ALA A C 1 ATOM 6132 O O . ALA A 1 773 ? 39.162 67.198 -30.923 1.00 9.19 ? 773 ALA A O 1 ATOM 6133 C CB . ALA A 1 773 ? 37.528 64.580 -30.750 1.00 12.40 ? 773 ALA A CB 1 ATOM 6134 N N . PRO A 1 774 ? 37.058 67.806 -31.345 1.00 7.98 ? 774 PRO A N 1 ATOM 6135 C CA . PRO A 1 774 ? 37.347 69.151 -30.813 1.00 8.57 ? 774 PRO A CA 1 ATOM 6136 C C . PRO A 1 774 ? 37.648 69.192 -29.324 1.00 7.99 ? 774 PRO A C 1 ATOM 6137 O O . PRO A 1 774 ? 37.293 68.274 -28.547 1.00 8.16 ? 774 PRO A O 1 ATOM 6138 C CB . PRO A 1 774 ? 36.068 69.952 -31.101 1.00 10.90 ? 774 PRO A CB 1 ATOM 6139 C CG . PRO A 1 774 ? 35.016 68.937 -31.131 1.00 13.58 ? 774 PRO A CG 1 ATOM 6140 C CD . PRO A 1 774 ? 35.700 67.694 -31.852 1.00 9.04 ? 774 PRO A CD 1 ATOM 6141 N N . GLU A 1 775 ? 38.291 70.264 -28.943 1.00 8.49 ? 775 GLU A N 1 ATOM 6142 C CA . GLU A 1 775 ? 38.542 70.568 -27.533 1.00 6.95 ? 775 GLU A CA 1 ATOM 6143 C C . GLU A 1 775 ? 37.585 71.691 -27.175 1.00 7.35 ? 775 GLU A C 1 ATOM 6144 O O . GLU A 1 775 ? 37.359 72.637 -28.000 1.00 9.98 ? 775 GLU A O 1 ATOM 6145 C CB . GLU A 1 775 ? 39.959 71.042 -27.317 1.00 8.64 ? 775 GLU A CB 1 ATOM 6146 C CG . GLU A 1 775 ? 40.236 71.455 -25.826 1.00 8.85 ? 775 GLU A CG 1 ATOM 6147 C CD . GLU A 1 775 ? 41.670 71.977 -25.546 1.00 16.22 ? 775 GLU A CD 1 ATOM 6148 O OE1 . GLU A 1 775 ? 42.512 71.989 -26.454 1.00 24.03 ? 775 GLU A OE1 1 ATOM 6149 O OE2 . GLU A 1 775 ? 41.956 72.388 -24.402 1.00 15.85 ? 775 GLU A OE2 1 ATOM 6150 N N . ILE A 1 776 ? 36.914 71.628 -26.053 1.00 7.15 ? 776 ILE A N 1 ATOM 6151 C CA . ILE A 1 776 ? 36.037 72.709 -25.603 1.00 7.40 ? 776 ILE A CA 1 ATOM 6152 C C . ILE A 1 776 ? 36.675 73.347 -24.379 1.00 6.93 ? 776 ILE A C 1 ATOM 6153 O O . ILE A 1 776 ? 37.152 72.612 -23.460 1.00 7.31 ? 776 ILE A O 1 ATOM 6154 C CB . ILE A 1 776 ? 34.649 72.161 -25.186 1.00 8.91 ? 776 ILE A CB 1 ATOM 6155 C CG1 . ILE A 1 776 ? 34.088 71.210 -26.239 1.00 11.05 ? 776 ILE A CG1 1 ATOM 6156 C CG2 . ILE A 1 776 ? 33.725 73.328 -24.745 1.00 11.34 ? 776 ILE A CG2 1 ATOM 6157 C CD1 . ILE A 1 776 ? 34.026 71.758 -27.686 1.00 14.51 ? 776 ILE A CD1 1 ATOM 6158 N N . ARG A 1 777 ? 36.720 74.670 -24.330 1.00 7.44 ? 777 ARG A N 1 ATOM 6159 C CA . ARG A 1 777 ? 37.200 75.357 -23.123 1.00 7.89 ? 777 ARG A CA 1 ATOM 6160 C C . ARG A 1 777 ? 36.143 76.353 -22.692 1.00 8.20 ? 777 ARG A C 1 ATOM 6161 O O . ARG A 1 777 ? 35.612 77.119 -23.543 1.00 8.76 ? 777 ARG A O 1 ATOM 6162 C CB . ARG A 1 777 ? 38.496 76.111 -23.374 1.00 9.53 ? 777 ARG A CB 1 ATOM 6163 C CG . ARG A 1 777 ? 39.615 75.234 -23.758 1.00 8.28 ? 777 ARG A CG 1 ATOM 6164 C CD . ARG A 1 777 ? 40.949 76.002 -23.868 1.00 9.84 ? 777 ARG A CD 1 ATOM 6165 N NE . ARG A 1 777 ? 42.020 75.146 -24.366 1.00 12.15 ? 777 ARG A NE 1 ATOM 6166 C CZ . ARG A 1 777 ? 43.200 75.566 -24.813 1.00 13.37 ? 777 ARG A CZ 1 ATOM 6167 N NH1 . ARG A 1 777 ? 43.459 76.880 -24.765 1.00 15.38 ? 777 ARG A NH1 1 ATOM 6168 N NH2 . ARG A 1 777 ? 44.059 74.720 -25.381 1.00 15.68 ? 777 ARG A NH2 1 ATOM 6169 N N . ASN A 1 778 ? 35.775 76.365 -21.418 1.00 6.08 ? 778 ASN A N 1 ATOM 6170 C CA . ASN A 1 778 ? 34.845 77.355 -20.930 1.00 6.66 ? 778 ASN A CA 1 ATOM 6171 C C . ASN A 1 778 ? 35.528 78.173 -19.832 1.00 6.69 ? 778 ASN A C 1 ATOM 6172 O O . ASN A 1 778 ? 35.962 77.587 -18.795 1.00 7.42 ? 778 ASN A O 1 ATOM 6173 C CB . ASN A 1 778 ? 33.631 76.679 -20.245 1.00 8.16 ? 778 ASN A CB 1 ATOM 6174 C CG . ASN A 1 778 ? 32.690 75.984 -21.186 1.00 8.32 ? 778 ASN A CG 1 ATOM 6175 O OD1 . ASN A 1 778 ? 32.635 76.353 -22.375 1.00 9.27 ? 778 ASN A OD1 1 ATOM 6176 N ND2 . ASN A 1 778 ? 31.913 75.037 -20.677 1.00 7.91 ? 778 ASN A ND2 1 ATOM 6177 N N . LEU A 1 779 ? 35.591 79.494 -20.007 1.00 7.34 ? 779 LEU A N 1 ATOM 6178 C CA . LEU A 1 779 ? 36.110 80.366 -18.910 1.00 7.61 ? 779 LEU A CA 1 ATOM 6179 C C . LEU A 1 779 ? 34.859 80.797 -18.188 1.00 6.67 ? 779 LEU A C 1 ATOM 6180 O O . LEU A 1 779 ? 34.054 81.593 -18.719 1.00 7.85 ? 779 LEU A O 1 ATOM 6181 C CB . LEU A 1 779 ? 36.844 81.548 -19.537 1.00 8.90 ? 779 LEU A CB 1 ATOM 6182 C CG . LEU A 1 779 ? 37.381 82.547 -18.493 1.00 11.76 ? 779 LEU A CG 1 ATOM 6183 C CD1 . LEU A 1 779 ? 38.344 81.929 -17.601 1.00 16.56 ? 779 LEU A CD1 1 ATOM 6184 C CD2 . LEU A 1 779 ? 37.973 83.768 -19.294 1.00 19.02 ? 779 LEU A CD2 1 ATOM 6185 N N . VAL A 1 780 ? 34.643 80.192 -17.019 1.00 7.61 ? 780 VAL A N 1 ATOM 6186 C CA . VAL A 1 780 ? 33.385 80.380 -16.285 1.00 8.46 ? 780 VAL A CA 1 ATOM 6187 C C . VAL A 1 780 ? 33.523 81.378 -15.148 1.00 8.12 ? 780 VAL A C 1 ATOM 6188 O O . VAL A 1 780 ? 34.339 81.173 -14.223 1.00 9.41 ? 780 VAL A O 1 ATOM 6189 C CB . VAL A 1 780 ? 32.916 78.992 -15.728 1.00 7.83 ? 780 VAL A CB 1 ATOM 6190 C CG1 . VAL A 1 780 ? 31.589 79.135 -15.004 1.00 10.37 ? 780 VAL A CG1 1 ATOM 6191 C CG2 . VAL A 1 780 ? 32.829 77.964 -16.854 1.00 8.77 ? 780 VAL A CG2 1 ATOM 6192 N N . ASP A 1 781 ? 32.758 82.473 -15.231 1.00 7.99 ? 781 ASP A N 1 ATOM 6193 C CA . ASP A 1 781 ? 32.756 83.483 -14.155 1.00 9.80 ? 781 ASP A CA 1 ATOM 6194 C C . ASP A 1 781 ? 31.331 83.787 -13.786 1.00 9.33 ? 781 ASP A C 1 ATOM 6195 O O . ASP A 1 781 ? 30.664 84.635 -14.444 1.00 9.99 ? 781 ASP A O 1 ATOM 6196 C CB . ASP A 1 781 ? 33.458 84.757 -14.635 1.00 11.42 ? 781 ASP A CB 1 ATOM 6197 C CG . ASP A 1 781 ? 33.518 85.796 -13.549 1.00 14.20 ? 781 ASP A CG 1 ATOM 6198 O OD1 . ASP A 1 781 ? 33.087 85.571 -12.395 1.00 13.54 ? 781 ASP A OD1 1 ATOM 6199 O OD2 . ASP A 1 781 ? 34.036 86.909 -13.868 1.00 20.77 ? 781 ASP A OD2 1 ATOM 6200 N N . ILE A 1 782 ? 30.790 83.075 -12.809 1.00 9.64 ? 782 ILE A N 1 ATOM 6201 C CA . ILE A 1 782 ? 29.388 83.219 -12.399 1.00 11.03 ? 782 ILE A CA 1 ATOM 6202 C C . ILE A 1 782 ? 29.140 84.562 -11.738 1.00 14.80 ? 782 ILE A C 1 ATOM 6203 O O . ILE A 1 782 ? 27.988 84.941 -11.481 1.00 15.99 ? 782 ILE A O 1 ATOM 6204 C CB . ILE A 1 782 ? 29.022 82.016 -11.508 1.00 11.47 ? 782 ILE A CB 1 ATOM 6205 C CG1 . ILE A 1 782 ? 27.537 81.860 -11.356 1.00 12.47 ? 782 ILE A CG1 1 ATOM 6206 C CG2 . ILE A 1 782 ? 29.723 82.171 -10.130 1.00 13.80 ? 782 ILE A CG2 1 ATOM 6207 C CD1 . ILE A 1 782 ? 27.229 80.390 -10.902 1.00 14.98 ? 782 ILE A CD1 1 ATOM 6208 N N . GLY A 1 783 ? 30.207 85.294 -11.455 1.00 13.09 ? 783 GLY A N 1 ATOM 6209 C CA . GLY A 1 783 ? 30.032 86.678 -11.006 1.00 15.88 ? 783 GLY A CA 1 ATOM 6210 C C . GLY A 1 783 ? 29.200 86.795 -9.760 1.00 16.13 ? 783 GLY A C 1 ATOM 6211 O O . GLY A 1 783 ? 29.422 86.034 -8.794 1.00 18.55 ? 783 GLY A O 1 ATOM 6212 N N . SER A 1 784 ? 28.230 87.690 -9.788 1.00 18.87 ? 784 SER A N 1 ATOM 6213 C CA . SER A 1 784 ? 27.397 87.868 -8.597 1.00 18.78 ? 784 SER A CA 1 ATOM 6214 C C . SER A 1 784 ? 26.027 87.219 -8.742 1.00 20.64 ? 784 SER A C 1 ATOM 6215 O O . SER A 1 784 ? 25.086 87.629 -8.034 1.00 21.13 ? 784 SER A O 1 ATOM 6216 C CB . SER A 1 784 ? 27.241 89.363 -8.283 1.00 23.50 ? 784 SER A CB 1 ATOM 6217 O OG . SER A 1 784 ? 26.667 90.034 -9.382 1.00 31.45 ? 784 SER A OG 1 ATOM 6218 N N . LEU A 1 785 ? 25.881 86.225 -9.629 1.00 18.32 ? 785 LEU A N 1 ATOM 6219 C CA . LEU A 1 785 ? 24.578 85.581 -9.808 1.00 16.55 ? 785 LEU A CA 1 ATOM 6220 C C . LEU A 1 785 ? 24.222 84.621 -8.661 1.00 18.60 ? 785 LEU A C 1 ATOM 6221 O O . LEU A 1 785 ? 24.396 83.367 -8.758 1.00 18.68 ? 785 LEU A O 1 ATOM 6222 C CB . LEU A 1 785 ? 24.559 84.795 -11.129 1.00 16.14 ? 785 LEU A CB 1 ATOM 6223 C CG . LEU A 1 785 ? 24.779 85.626 -12.421 1.00 18.08 ? 785 LEU A CG 1 ATOM 6224 C CD1 . LEU A 1 785 ? 24.729 84.755 -13.626 1.00 21.25 ? 785 LEU A CD1 1 ATOM 6225 C CD2 . LEU A 1 785 ? 23.726 86.751 -12.538 1.00 21.50 ? 785 LEU A CD2 1 ATOM 6226 N N . ASP A 1 786 ? 23.636 85.150 -7.585 1.00 18.03 ? 786 ASP A N 1 ATOM 6227 C CA . ASP A 1 786 ? 23.313 84.322 -6.436 1.00 15.92 ? 786 ASP A CA 1 ATOM 6228 C C . ASP A 1 786 ? 22.194 83.295 -6.812 1.00 12.07 ? 786 ASP A C 1 ATOM 6229 O O . ASP A 1 786 ? 21.370 83.486 -7.707 1.00 14.36 ? 786 ASP A O 1 ATOM 6230 C CB . ASP A 1 786 ? 22.815 85.157 -5.235 1.00 19.37 ? 786 ASP A CB 1 ATOM 6231 C CG . ASP A 1 786 ? 23.936 85.892 -4.501 1.00 23.83 ? 786 ASP A CG 1 ATOM 6232 O OD1 . ASP A 1 786 ? 25.104 86.038 -4.980 1.00 20.58 ? 786 ASP A OD1 1 ATOM 6233 O OD2 . ASP A 1 786 ? 23.618 86.349 -3.385 1.00 27.35 ? 786 ASP A OD2 1 ATOM 6234 N N . ASN A 1 787 ? 22.280 82.204 -6.088 1.00 13.73 ? 787 ASN A N 1 ATOM 6235 C CA . ASN A 1 787 ? 21.345 81.098 -6.211 1.00 11.79 ? 787 ASN A CA 1 ATOM 6236 C C . ASN A 1 787 ? 21.142 80.645 -7.639 1.00 11.07 ? 787 ASN A C 1 ATOM 6237 O O . ASN A 1 787 ? 20.025 80.470 -8.121 1.00 11.27 ? 787 ASN A O 1 ATOM 6238 C CB . ASN A 1 787 ? 20.007 81.478 -5.545 1.00 11.53 ? 787 ASN A CB 1 ATOM 6239 C CG . ASN A 1 787 ? 20.195 81.706 -4.099 1.00 17.13 ? 787 ASN A CG 1 ATOM 6240 O OD1 . ASN A 1 787 ? 20.973 80.972 -3.448 1.00 18.25 ? 787 ASN A OD1 1 ATOM 6241 N ND2 . ASN A 1 787 ? 19.536 82.744 -3.561 1.00 24.18 ? 787 ASN A ND2 1 ATOM 6242 N N . THR A 1 788 ? 22.281 80.426 -8.296 1.00 9.55 ? 788 THR A N 1 ATOM 6243 C CA . THR A 1 788 ? 22.280 79.987 -9.680 1.00 10.51 ? 788 THR A CA 1 ATOM 6244 C C . THR A 1 788 ? 23.330 78.864 -9.902 1.00 8.84 ? 788 THR A C 1 ATOM 6245 O O . THR A 1 788 ? 24.442 78.964 -9.342 1.00 9.09 ? 788 THR A O 1 ATOM 6246 C CB . THR A 1 788 ? 22.711 81.184 -10.594 1.00 12.81 ? 788 THR A CB 1 ATOM 6247 O OG1 . THR A 1 788 ? 21.763 82.267 -10.452 1.00 13.82 ? 788 THR A OG1 1 ATOM 6248 C CG2 . THR A 1 788 ? 22.679 80.795 -12.089 1.00 14.19 ? 788 THR A CG2 1 ATOM 6249 N N . GLU A 1 789 ? 22.968 77.857 -10.683 1.00 8.55 ? 789 GLU A N 1 ATOM 6250 C CA . GLU A 1 789 ? 23.927 76.808 -11.067 1.00 7.38 ? 789 GLU A CA 1 ATOM 6251 C C . GLU A 1 789 ? 23.927 76.838 -12.589 1.00 7.50 ? 789 GLU A C 1 ATOM 6252 O O . GLU A 1 789 ? 22.835 76.754 -13.207 1.00 9.33 ? 789 GLU A O 1 ATOM 6253 C CB . GLU A 1 789 ? 23.548 75.408 -10.519 1.00 8.28 ? 789 GLU A CB 1 ATOM 6254 C CG . GLU A 1 789 ? 23.117 75.447 -9.053 1.00 9.39 ? 789 GLU A CG 1 ATOM 6255 C CD . GLU A 1 789 ? 23.316 74.169 -8.280 1.00 8.67 ? 789 GLU A CD 1 ATOM 6256 O OE1 . GLU A 1 789 ? 24.159 73.344 -8.754 1.00 9.34 ? 789 GLU A OE1 1 ATOM 6257 O OE2 . GLU A 1 789 ? 22.684 74.042 -7.202 1.00 8.81 ? 789 GLU A OE2 1 ATOM 6258 N N . ILE A 1 790 ? 25.085 77.014 -13.214 1.00 6.79 ? 790 ILE A N 1 ATOM 6259 C CA . ILE A 1 790 ? 25.181 77.076 -14.664 1.00 8.10 ? 790 ILE A CA 1 ATOM 6260 C C . ILE A 1 790 ? 25.535 75.695 -15.208 1.00 7.50 ? 790 ILE A C 1 ATOM 6261 O O . ILE A 1 790 ? 26.530 75.094 -14.764 1.00 8.23 ? 790 ILE A O 1 ATOM 6262 C CB . ILE A 1 790 ? 26.256 78.071 -15.096 1.00 9.67 ? 790 ILE A CB 1 ATOM 6263 C CG1 . ILE A 1 790 ? 25.860 79.516 -14.693 1.00 14.02 ? 790 ILE A CG1 1 ATOM 6264 C CG2 . ILE A 1 790 ? 26.491 77.981 -16.622 1.00 11.66 ? 790 ILE A CG2 1 ATOM 6265 C CD1 . ILE A 1 790 ? 27.064 80.469 -14.795 1.00 23.94 ? 790 ILE A CD1 1 ATOM 6266 N N . VAL A 1 791 ? 24.741 75.185 -16.131 1.00 6.98 ? 791 VAL A N 1 ATOM 6267 C CA . VAL A 1 791 ? 24.976 73.887 -16.732 1.00 7.31 ? 791 VAL A CA 1 ATOM 6268 C C . VAL A 1 791 ? 25.234 73.971 -18.211 1.00 7.58 ? 791 VAL A C 1 ATOM 6269 O O . VAL A 1 791 ? 24.647 74.859 -18.922 1.00 7.69 ? 791 VAL A O 1 ATOM 6270 C CB . VAL A 1 791 ? 23.755 72.940 -16.440 1.00 7.52 ? 791 VAL A CB 1 ATOM 6271 C CG1 . VAL A 1 791 ? 22.498 73.412 -17.241 1.00 10.00 ? 791 VAL A CG1 1 ATOM 6272 C CG2 . VAL A 1 791 ? 24.102 71.468 -16.778 1.00 9.22 ? 791 VAL A CG2 1 ATOM 6273 N N . MET A 1 792 ? 26.129 73.136 -18.708 1.00 6.68 ? 792 MET A N 1 ATOM 6274 C CA . MET A 1 792 ? 26.387 73.019 -20.145 1.00 6.48 ? 792 MET A CA 1 ATOM 6275 C C . MET A 1 792 ? 25.725 71.727 -20.601 1.00 6.88 ? 792 MET A C 1 ATOM 6276 O O . MET A 1 792 ? 26.051 70.618 -20.092 1.00 8.16 ? 792 MET A O 1 ATOM 6277 C CB . MET A 1 792 ? 27.893 72.997 -20.446 1.00 7.60 ? 792 MET A CB 1 ATOM 6278 C CG . MET A 1 792 ? 28.188 72.837 -21.982 1.00 8.20 ? 792 MET A CG 1 ATOM 6279 S SD . MET A 1 792 ? 29.964 72.873 -22.300 1.00 8.99 ? 792 MET A SD 1 ATOM 6280 C CE . MET A 1 792 ? 30.497 71.373 -21.500 1.00 10.64 ? 792 MET A CE 1 ATOM 6281 N N . ARG A 1 793 ? 24.791 71.812 -21.546 1.00 7.08 ? 793 ARG A N 1 ATOM 6282 C CA . ARG A 1 793 ? 24.080 70.630 -22.050 1.00 8.02 ? 793 ARG A CA 1 ATOM 6283 C C . ARG A 1 793 ? 24.406 70.413 -23.508 1.00 6.94 ? 793 ARG A C 1 ATOM 6284 O O . ARG A 1 793 ? 24.624 71.363 -24.298 1.00 8.17 ? 793 ARG A O 1 ATOM 6285 C CB . ARG A 1 793 ? 22.567 70.854 -21.888 1.00 7.91 ? 793 ARG A CB 1 ATOM 6286 C CG . ARG A 1 793 ? 21.695 69.635 -22.322 1.00 7.65 ? 793 ARG A CG 1 ATOM 6287 C CD . ARG A 1 793 ? 20.206 69.880 -22.059 1.00 8.63 ? 793 ARG A CD 1 ATOM 6288 N NE . ARG A 1 793 ? 19.957 69.934 -20.614 1.00 8.88 ? 793 ARG A NE 1 ATOM 6289 C CZ . ARG A 1 793 ? 18.899 70.524 -20.066 1.00 9.39 ? 793 ARG A CZ 1 ATOM 6290 N NH1 . ARG A 1 793 ? 17.975 71.104 -20.856 1.00 10.52 ? 793 ARG A NH1 1 ATOM 6291 N NH2 . ARG A 1 793 ? 18.760 70.585 -18.769 1.00 9.31 ? 793 ARG A NH2 1 ATOM 6292 N N . LEU A 1 794 ? 24.475 69.154 -23.888 1.00 7.41 ? 794 LEU A N 1 ATOM 6293 C CA . LEU A 1 794 ? 24.590 68.701 -25.287 1.00 8.05 ? 794 LEU A CA 1 ATOM 6294 C C . LEU A 1 794 ? 23.274 68.028 -25.671 1.00 8.93 ? 794 LEU A C 1 ATOM 6295 O O . LEU A 1 794 ? 22.785 67.112 -24.967 1.00 9.37 ? 794 LEU A O 1 ATOM 6296 C CB . LEU A 1 794 ? 25.701 67.672 -25.448 1.00 10.05 ? 794 LEU A CB 1 ATOM 6297 C CG . LEU A 1 794 ? 27.061 68.333 -25.526 1.00 10.10 ? 794 LEU A CG 1 ATOM 6298 C CD1 . LEU A 1 794 ? 28.178 67.380 -25.086 1.00 11.19 ? 794 LEU A CD1 1 ATOM 6299 C CD2 . LEU A 1 794 ? 27.247 68.792 -26.969 1.00 13.62 ? 794 LEU A CD2 1 ATOM 6300 N N . GLU A 1 795 ? 22.679 68.489 -26.769 1.00 9.33 ? 795 GLU A N 1 ATOM 6301 C CA . GLU A 1 795 ? 21.407 67.930 -27.265 1.00 9.06 ? 795 GLU A CA 1 ATOM 6302 C C . GLU A 1 795 ? 21.691 67.221 -28.567 1.00 9.38 ? 795 GLU A C 1 ATOM 6303 O O . GLU A 1 795 ? 22.261 67.798 -29.499 1.00 11.53 ? 795 GLU A O 1 ATOM 6304 C CB . GLU A 1 795 ? 20.389 69.051 -27.517 1.00 10.76 ? 795 GLU A CB 1 ATOM 6305 C CG . GLU A 1 795 ? 19.962 69.778 -26.261 1.00 13.78 ? 795 GLU A CG 1 ATOM 6306 C CD . GLU A 1 795 ? 19.087 71.031 -26.516 1.00 18.24 ? 795 GLU A CD 1 ATOM 6307 O OE1 . GLU A 1 795 ? 19.159 71.640 -27.622 1.00 22.49 ? 795 GLU A OE1 1 ATOM 6308 O OE2 . GLU A 1 795 ? 18.368 71.458 -25.593 1.00 19.64 ? 795 GLU A OE2 1 ATOM 6309 N N . THR A 1 796 ? 21.349 65.918 -28.621 1.00 8.95 ? 796 THR A N 1 ATOM 6310 C CA . THR A 1 796 ? 21.537 65.135 -29.829 1.00 9.00 ? 796 THR A CA 1 ATOM 6311 C C . THR A 1 796 ? 20.210 64.385 -30.035 1.00 8.60 ? 796 THR A C 1 ATOM 6312 O O . THR A 1 796 ? 19.272 64.454 -29.233 1.00 11.24 ? 796 THR A O 1 ATOM 6313 C CB . THR A 1 796 ? 22.690 64.070 -29.723 1.00 9.50 ? 796 THR A CB 1 ATOM 6314 O OG1 . THR A 1 796 ? 22.244 62.917 -28.977 1.00 8.90 ? 796 THR A OG1 1 ATOM 6315 C CG2 . THR A 1 796 ? 23.906 64.671 -29.016 1.00 11.82 ? 796 THR A CG2 1 ATOM 6316 N N . HIS A 1 797 ? 20.223 63.651 -31.138 1.00 10.21 ? 797 HIS A N 1 ATOM 6317 C CA . HIS A 1 797 ? 19.041 62.791 -31.452 1.00 9.20 ? 797 HIS A CA 1 ATOM 6318 C C . HIS A 1 797 ? 19.406 61.335 -31.247 1.00 10.89 ? 797 HIS A C 1 ATOM 6319 O O . HIS A 1 797 ? 18.635 60.445 -31.660 1.00 12.74 ? 797 HIS A O 1 ATOM 6320 C CB . HIS A 1 797 ? 18.530 63.102 -32.880 1.00 10.02 ? 797 HIS A CB 1 ATOM 6321 C CG . HIS A 1 797 ? 18.072 64.519 -33.015 1.00 9.41 ? 797 HIS A CG 1 ATOM 6322 N ND1 . HIS A 1 797 ? 17.808 65.135 -34.225 1.00 12.20 ? 797 HIS A ND1 1 ATOM 6323 C CD2 . HIS A 1 797 ? 17.809 65.440 -32.060 1.00 12.11 ? 797 HIS A CD2 1 ATOM 6324 C CE1 . HIS A 1 797 ? 17.403 66.368 -33.996 1.00 14.26 ? 797 HIS A CE1 1 ATOM 6325 N NE2 . HIS A 1 797 ? 17.396 66.586 -32.694 1.00 16.58 ? 797 HIS A NE2 1 ATOM 6326 N N . ILE A 1 798 ? 20.537 61.021 -30.571 1.00 10.25 ? 798 ILE A N 1 ATOM 6327 C CA . ILE A 1 798 ? 20.930 59.636 -30.275 1.00 8.61 ? 798 ILE A CA 1 ATOM 6328 C C . ILE A 1 798 ? 19.827 59.034 -29.398 1.00 8.83 ? 798 ILE A C 1 ATOM 6329 O O . ILE A 1 798 ? 19.315 59.633 -28.457 1.00 9.43 ? 798 ILE A O 1 ATOM 6330 C CB . ILE A 1 798 ? 22.264 59.661 -29.497 1.00 8.91 ? 798 ILE A CB 1 ATOM 6331 C CG1 . ILE A 1 798 ? 23.352 60.183 -30.413 1.00 10.85 ? 798 ILE A CG1 1 ATOM 6332 C CG2 . ILE A 1 798 ? 22.592 58.231 -28.936 1.00 10.59 ? 798 ILE A CG2 1 ATOM 6333 C CD1 . ILE A 1 798 ? 24.804 60.373 -29.726 1.00 13.94 ? 798 ILE A CD1 1 ATOM 6334 N N . ASP A 1 799 ? 19.392 57.802 -29.783 1.00 10.22 ? 799 ASP A N 1 ATOM 6335 C CA . ASP A 1 799 ? 18.310 57.136 -29.059 1.00 9.64 ? 799 ASP A CA 1 ATOM 6336 C C . ASP A 1 799 ? 18.824 56.340 -27.861 1.00 10.69 ? 799 ASP A C 1 ATOM 6337 O O . ASP A 1 799 ? 18.857 55.129 -27.858 1.00 11.13 ? 799 ASP A O 1 ATOM 6338 C CB . ASP A 1 799 ? 17.495 56.240 -30.033 1.00 12.22 ? 799 ASP A CB 1 ATOM 6339 C CG . ASP A 1 799 ? 16.254 55.638 -29.357 1.00 13.43 ? 799 ASP A CG 1 ATOM 6340 O OD1 . ASP A 1 799 ? 15.877 55.967 -28.209 1.00 18.56 ? 799 ASP A OD1 1 ATOM 6341 O OD2 . ASP A 1 799 ? 15.717 54.711 -29.981 1.00 20.94 ? 799 ASP A OD2 1 ATOM 6342 N N . SER A 1 800 ? 19.294 57.087 -26.860 1.00 10.08 ? 800 SER A N 1 ATOM 6343 C CA . SER A 1 800 ? 19.873 56.483 -25.657 1.00 9.61 ? 800 SER A CA 1 ATOM 6344 C C . SER A 1 800 ? 18.825 56.088 -24.666 1.00 10.43 ? 800 SER A C 1 ATOM 6345 O O . SER A 1 800 ? 19.139 55.311 -23.731 1.00 9.62 ? 800 SER A O 1 ATOM 6346 C CB . SER A 1 800 ? 20.886 57.501 -25.024 1.00 9.80 ? 800 SER A CB 1 ATOM 6347 O OG . SER A 1 800 ? 20.271 58.726 -24.713 1.00 9.39 ? 800 SER A OG 1 ATOM 6348 N N . GLY A 1 801 ? 17.605 56.598 -24.768 1.00 9.15 ? 801 GLY A N 1 ATOM 6349 C CA . GLY A 1 801 ? 16.572 56.227 -23.821 1.00 9.96 ? 801 GLY A CA 1 ATOM 6350 C C . GLY A 1 801 ? 16.869 56.742 -22.439 1.00 9.84 ? 801 GLY A C 1 ATOM 6351 O O . GLY A 1 801 ? 16.974 57.956 -22.262 1.00 11.22 ? 801 GLY A O 1 ATOM 6352 N N . ASP A 1 802 ? 16.947 55.861 -21.456 1.00 9.38 ? 802 ASP A N 1 ATOM 6353 C CA . ASP A 1 802 ? 17.243 56.217 -20.074 1.00 9.08 ? 802 ASP A CA 1 ATOM 6354 C C . ASP A 1 802 ? 18.636 55.765 -19.665 1.00 8.23 ? 802 ASP A C 1 ATOM 6355 O O . ASP A 1 802 ? 18.940 55.807 -18.467 1.00 9.94 ? 802 ASP A O 1 ATOM 6356 C CB . ASP A 1 802 ? 16.167 55.587 -19.126 1.00 11.12 ? 802 ASP A CB 1 ATOM 6357 C CG . ASP A 1 802 ? 16.050 54.074 -19.260 1.00 11.75 ? 802 ASP A CG 1 ATOM 6358 O OD1 . ASP A 1 802 ? 16.801 53.417 -19.982 1.00 14.31 ? 802 ASP A OD1 1 ATOM 6359 O OD2 . ASP A 1 802 ? 15.142 53.571 -18.542 1.00 16.10 ? 802 ASP A OD2 1 ATOM 6360 N N . ILE A 1 803 ? 19.504 55.410 -20.588 1.00 6.73 ? 803 ILE A N 1 ATOM 6361 C CA . ILE A 1 803 ? 20.827 54.884 -20.244 1.00 7.62 ? 803 ILE A CA 1 ATOM 6362 C C . ILE A 1 803 ? 21.920 55.910 -20.547 1.00 7.47 ? 803 ILE A C 1 ATOM 6363 O O . ILE A 1 803 ? 21.884 56.595 -21.576 1.00 7.26 ? 803 ILE A O 1 ATOM 6364 C CB . ILE A 1 803 ? 21.122 53.594 -21.082 1.00 7.53 ? 803 ILE A CB 1 ATOM 6365 C CG1 . ILE A 1 803 ? 20.092 52.467 -20.709 1.00 10.42 ? 803 ILE A CG1 1 ATOM 6366 C CG2 . ILE A 1 803 ? 22.567 53.082 -20.813 1.00 9.53 ? 803 ILE A CG2 1 ATOM 6367 C CD1 . ILE A 1 803 ? 20.064 52.122 -19.213 1.00 12.96 ? 803 ILE A CD1 1 ATOM 6368 N N . PHE A 1 804 ? 22.917 56.008 -19.655 1.00 7.46 ? 804 PHE A N 1 ATOM 6369 C CA . PHE A 1 804 ? 24.094 56.809 -19.923 1.00 6.54 ? 804 PHE A CA 1 ATOM 6370 C C . PHE A 1 804 ? 25.240 56.187 -19.093 1.00 6.73 ? 804 PHE A C 1 ATOM 6371 O O . PHE A 1 804 ? 24.978 55.298 -18.283 1.00 7.84 ? 804 PHE A O 1 ATOM 6372 C CB . PHE A 1 804 ? 23.863 58.323 -19.595 1.00 6.53 ? 804 PHE A CB 1 ATOM 6373 C CG . PHE A 1 804 ? 23.435 58.631 -18.190 1.00 6.33 ? 804 PHE A CG 1 ATOM 6374 C CD1 . PHE A 1 804 ? 22.164 58.432 -17.710 1.00 7.13 ? 804 PHE A CD1 1 ATOM 6375 C CD2 . PHE A 1 804 ? 24.384 59.250 -17.323 1.00 6.21 ? 804 PHE A CD2 1 ATOM 6376 C CE1 . PHE A 1 804 ? 21.803 58.815 -16.424 1.00 7.24 ? 804 PHE A CE1 1 ATOM 6377 C CE2 . PHE A 1 804 ? 24.043 59.650 -16.051 1.00 6.57 ? 804 PHE A CE2 1 ATOM 6378 C CZ . PHE A 1 804 ? 22.759 59.449 -15.574 1.00 7.05 ? 804 PHE A CZ 1 ATOM 6379 N N . TYR A 1 805 ? 26.442 56.634 -19.332 1.00 6.42 ? 805 TYR A N 1 ATOM 6380 C CA . TYR A 1 805 ? 27.612 56.068 -18.649 1.00 5.91 ? 805 TYR A CA 1 ATOM 6381 C C . TYR A 1 805 ? 28.445 57.195 -18.084 1.00 6.79 ? 805 TYR A C 1 ATOM 6382 O O . TYR A 1 805 ? 28.587 58.235 -18.727 1.00 6.78 ? 805 TYR A O 1 ATOM 6383 C CB . TYR A 1 805 ? 28.473 55.276 -19.646 1.00 7.25 ? 805 TYR A CB 1 ATOM 6384 C CG . TYR A 1 805 ? 27.766 54.063 -20.219 1.00 6.02 ? 805 TYR A CG 1 ATOM 6385 C CD1 . TYR A 1 805 ? 26.817 54.189 -21.221 1.00 8.67 ? 805 TYR A CD1 1 ATOM 6386 C CD2 . TYR A 1 805 ? 28.045 52.800 -19.716 1.00 7.50 ? 805 TYR A CD2 1 ATOM 6387 C CE1 . TYR A 1 805 ? 26.173 53.033 -21.705 1.00 8.40 ? 805 TYR A CE1 1 ATOM 6388 C CE2 . TYR A 1 805 ? 27.404 51.639 -20.214 1.00 9.35 ? 805 TYR A CE2 1 ATOM 6389 C CZ . TYR A 1 805 ? 26.487 51.821 -21.192 1.00 8.32 ? 805 TYR A CZ 1 ATOM 6390 O OH . TYR A 1 805 ? 25.851 50.697 -21.742 1.00 10.75 ? 805 TYR A OH 1 ATOM 6391 N N . THR A 1 806 ? 28.933 56.980 -16.862 1.00 6.63 ? 806 THR A N 1 ATOM 6392 C CA . THR A 1 806 ? 29.822 57.969 -16.201 1.00 5.94 ? 806 THR A CA 1 ATOM 6393 C C . THR A 1 806 ? 30.994 57.230 -15.632 1.00 6.68 ? 806 THR A C 1 ATOM 6394 O O . THR A 1 806 ? 30.923 56.016 -15.410 1.00 7.72 ? 806 THR A O 1 ATOM 6395 C CB . THR A 1 806 ? 29.100 58.784 -15.119 1.00 7.12 ? 806 THR A CB 1 ATOM 6396 O OG1 . THR A 1 806 ? 28.721 57.889 -14.075 1.00 7.35 ? 806 THR A OG1 1 ATOM 6397 C CG2 . THR A 1 806 ? 27.837 59.470 -15.656 1.00 7.22 ? 806 THR A CG2 1 ATOM 6398 N N . ASP A 1 807 ? 32.122 57.894 -15.443 1.00 6.13 ? 807 ASP A N 1 ATOM 6399 C CA . ASP A 1 807 ? 33.244 57.168 -14.859 1.00 6.77 ? 807 ASP A CA 1 ATOM 6400 C C . ASP A 1 807 ? 33.306 57.248 -13.333 1.00 6.41 ? 807 ASP A C 1 ATOM 6401 O O . ASP A 1 807 ? 32.652 58.078 -12.682 1.00 6.88 ? 807 ASP A O 1 ATOM 6402 C CB . ASP A 1 807 ? 34.546 57.633 -15.451 1.00 9.22 ? 807 ASP A CB 1 ATOM 6403 C CG . ASP A 1 807 ? 34.982 58.914 -14.943 1.00 8.64 ? 807 ASP A CG 1 ATOM 6404 O OD1 . ASP A 1 807 ? 34.239 59.916 -15.032 1.00 9.86 ? 807 ASP A OD1 1 ATOM 6405 O OD2 . ASP A 1 807 ? 36.151 58.974 -14.449 1.00 11.05 ? 807 ASP A OD2 1 ATOM 6406 N N . LEU A 1 808 ? 34.052 56.301 -12.779 1.00 5.94 ? 808 LEU A N 1 ATOM 6407 C CA . LEU A 1 808 ? 34.348 56.306 -11.319 1.00 5.55 ? 808 LEU A CA 1 ATOM 6408 C C . LEU A 1 808 ? 35.844 56.504 -11.139 1.00 5.44 ? 808 LEU A C 1 ATOM 6409 O O . LEU A 1 808 ? 36.637 55.684 -11.616 1.00 6.02 ? 808 LEU A O 1 ATOM 6410 C CB . LEU A 1 808 ? 33.893 54.973 -10.692 1.00 6.40 ? 808 LEU A CB 1 ATOM 6411 C CG . LEU A 1 808 ? 32.359 54.822 -10.604 1.00 6.96 ? 808 LEU A CG 1 ATOM 6412 C CD1 . LEU A 1 808 ? 32.046 53.357 -10.367 1.00 8.64 ? 808 LEU A CD1 1 ATOM 6413 C CD2 . LEU A 1 808 ? 31.799 55.646 -9.442 1.00 9.12 ? 808 LEU A CD2 1 ATOM 6414 N N . ASN A 1 809 ? 36.201 57.671 -10.627 1.00 4.87 ? 809 ASN A N 1 ATOM 6415 C CA . ASN A 1 809 ? 37.577 57.981 -10.256 1.00 5.56 ? 809 ASN A CA 1 ATOM 6416 C C . ASN A 1 809 ? 38.546 57.890 -11.419 1.00 4.80 ? 809 ASN A C 1 ATOM 6417 O O . ASN A 1 809 ? 39.714 57.644 -11.196 1.00 5.86 ? 809 ASN A O 1 ATOM 6418 C CB . ASN A 1 809 ? 38.031 57.075 -9.092 1.00 4.70 ? 809 ASN A CB 1 ATOM 6419 C CG . ASN A 1 809 ? 36.989 56.983 -8.014 1.00 5.58 ? 809 ASN A CG 1 ATOM 6420 O OD1 . ASN A 1 809 ? 36.153 56.105 -8.043 1.00 8.62 ? 809 ASN A OD1 1 ATOM 6421 N ND2 . ASN A 1 809 ? 37.009 57.918 -7.091 1.00 4.05 ? 809 ASN A ND2 1 ATOM 6422 N N . GLY A 1 810 ? 38.072 58.076 -12.650 1.00 5.33 ? 810 GLY A N 1 ATOM 6423 C CA . GLY A 1 810 ? 39.001 58.004 -13.794 1.00 6.73 ? 810 GLY A CA 1 ATOM 6424 C C . GLY A 1 810 ? 39.471 56.574 -14.056 1.00 7.12 ? 810 GLY A C 1 ATOM 6425 O O . GLY A 1 810 ? 40.446 56.399 -14.835 1.00 9.66 ? 810 GLY A O 1 ATOM 6426 N N . LEU A 1 811 ? 38.861 55.581 -13.421 1.00 6.38 ? 811 LEU A N 1 ATOM 6427 C CA . LEU A 1 811 ? 39.308 54.196 -13.535 1.00 6.48 ? 811 LEU A CA 1 ATOM 6428 C C . LEU A 1 811 ? 38.407 53.294 -14.390 1.00 7.54 ? 811 LEU A C 1 ATOM 6429 O O . LEU A 1 811 ? 38.938 52.388 -15.043 1.00 10.37 ? 811 LEU A O 1 ATOM 6430 C CB . LEU A 1 811 ? 39.363 53.601 -12.113 1.00 8.04 ? 811 LEU A CB 1 ATOM 6431 C CG . LEU A 1 811 ? 39.840 52.155 -11.933 1.00 9.49 ? 811 LEU A CG 1 ATOM 6432 C CD1 . LEU A 1 811 ? 41.285 52.020 -12.422 1.00 10.66 ? 811 LEU A CD1 1 ATOM 6433 C CD2 . LEU A 1 811 ? 39.713 51.697 -10.447 1.00 11.01 ? 811 LEU A CD2 1 ATOM 6434 N N . GLN A 1 812 ? 37.113 53.516 -14.371 1.00 6.17 ? 812 GLN A N 1 ATOM 6435 C CA . GLN A 1 812 ? 36.149 52.624 -15.032 1.00 7.18 ? 812 GLN A CA 1 ATOM 6436 C C . GLN A 1 812 ? 34.903 53.357 -15.345 1.00 6.84 ? 812 GLN A C 1 ATOM 6437 O O . GLN A 1 812 ? 34.642 54.421 -14.722 1.00 8.41 ? 812 GLN A O 1 ATOM 6438 C CB . GLN A 1 812 ? 35.801 51.460 -14.062 1.00 7.91 ? 812 GLN A CB 1 ATOM 6439 C CG . GLN A 1 812 ? 35.206 51.997 -12.710 1.00 10.23 ? 812 GLN A CG 1 ATOM 6440 C CD . GLN A 1 812 ? 34.911 50.856 -11.731 1.00 11.95 ? 812 GLN A CD 1 ATOM 6441 O OE1 . GLN A 1 812 ? 33.983 50.114 -11.915 1.00 11.85 ? 812 GLN A OE1 1 ATOM 6442 N NE2 . GLN A 1 812 ? 35.751 50.738 -10.677 1.00 14.43 ? 812 GLN A NE2 1 ATOM 6443 N N . PHE A 1 813 ? 34.161 52.900 -16.364 1.00 6.62 ? 813 PHE A N 1 ATOM 6444 C CA . PHE A 1 813 ? 32.875 53.488 -16.705 1.00 6.03 ? 813 PHE A CA 1 ATOM 6445 C C . PHE A 1 813 ? 31.759 52.594 -16.267 1.00 7.02 ? 813 PHE A C 1 ATOM 6446 O O . PHE A 1 813 ? 31.775 51.363 -16.551 1.00 8.57 ? 813 PHE A O 1 ATOM 6447 C CB . PHE A 1 813 ? 32.820 53.788 -18.208 1.00 7.03 ? 813 PHE A CB 1 ATOM 6448 C CG . PHE A 1 813 ? 33.590 55.035 -18.590 1.00 6.97 ? 813 PHE A CG 1 ATOM 6449 C CD1 . PHE A 1 813 ? 34.971 54.988 -18.675 1.00 7.40 ? 813 PHE A CD1 1 ATOM 6450 C CD2 . PHE A 1 813 ? 32.915 56.255 -18.814 1.00 7.63 ? 813 PHE A CD2 1 ATOM 6451 C CE1 . PHE A 1 813 ? 35.707 56.178 -18.952 1.00 9.37 ? 813 PHE A CE1 1 ATOM 6452 C CE2 . PHE A 1 813 ? 33.642 57.416 -19.086 1.00 10.20 ? 813 PHE A CE2 1 ATOM 6453 C CZ . PHE A 1 813 ? 35.010 57.338 -19.135 1.00 9.07 ? 813 PHE A CZ 1 ATOM 6454 N N . ILE A 1 814 ? 30.796 53.165 -15.590 1.00 6.69 ? 814 ILE A N 1 ATOM 6455 C CA . ILE A 1 814 ? 29.685 52.405 -15.066 1.00 6.01 ? 814 ILE A CA 1 ATOM 6456 C C . ILE A 1 814 ? 28.384 52.835 -15.737 1.00 6.26 ? 814 ILE A C 1 ATOM 6457 O O . ILE A 1 814 ? 28.134 54.041 -15.976 1.00 6.25 ? 814 ILE A O 1 ATOM 6458 C CB . ILE A 1 814 ? 29.639 52.568 -13.512 1.00 6.22 ? 814 ILE A CB 1 ATOM 6459 C CG1 . ILE A 1 814 ? 28.561 51.647 -12.940 1.00 6.88 ? 814 ILE A CG1 1 ATOM 6460 C CG2 . ILE A 1 814 ? 29.365 54.044 -13.053 1.00 6.79 ? 814 ILE A CG2 1 ATOM 6461 C CD1 . ILE A 1 814 ? 28.714 51.462 -11.378 1.00 8.93 ? 814 ILE A CD1 1 ATOM 6462 N N . LYS A 1 815 ? 27.531 51.842 -16.028 1.00 6.38 ? 815 LYS A N 1 ATOM 6463 C CA . LYS A 1 815 ? 26.223 52.129 -16.618 1.00 6.62 ? 815 LYS A CA 1 ATOM 6464 C C . LYS A 1 815 ? 25.288 52.753 -15.583 1.00 6.06 ? 815 LYS A C 1 ATOM 6465 O O . LYS A 1 815 ? 25.133 52.275 -14.453 1.00 7.28 ? 815 LYS A O 1 ATOM 6466 C CB . LYS A 1 815 ? 25.630 50.818 -17.116 1.00 7.86 ? 815 LYS A CB 1 ATOM 6467 C CG . LYS A 1 815 ? 24.318 50.991 -17.902 1.00 9.27 ? 815 LYS A CG 1 ATOM 6468 C CD . LYS A 1 815 ? 23.883 49.572 -18.437 1.00 13.06 ? 815 LYS A CD 1 ATOM 6469 C CE . LYS A 1 815 ? 22.683 49.614 -19.324 1.00 19.59 ? 815 LYS A CE 1 ATOM 6470 N NZ . LYS A 1 815 ? 22.483 48.162 -19.811 1.00 24.06 ? 815 LYS A NZ 1 ATOM 6471 N N . ARG A 1 816 ? 24.642 53.844 -15.980 1.00 6.72 ? 816 ARG A N 1 ATOM 6472 C CA . ARG A 1 816 ? 23.653 54.531 -15.213 1.00 6.21 ? 816 ARG A CA 1 ATOM 6473 C C . ARG A 1 816 ? 22.287 54.424 -15.910 1.00 7.14 ? 816 ARG A C 1 ATOM 6474 O O . ARG A 1 816 ? 22.211 54.375 -17.157 1.00 7.94 ? 816 ARG A O 1 ATOM 6475 C CB . ARG A 1 816 ? 23.936 56.067 -15.083 1.00 7.57 ? 816 ARG A CB 1 ATOM 6476 C CG . ARG A 1 816 ? 25.352 56.432 -14.564 1.00 7.76 ? 816 ARG A CG 1 ATOM 6477 C CD . ARG A 1 816 ? 25.537 55.789 -13.217 1.00 7.42 ? 816 ARG A CD 1 ATOM 6478 N NE . ARG A 1 816 ? 26.748 56.370 -12.582 1.00 6.78 ? 816 ARG A NE 1 ATOM 6479 C CZ . ARG A 1 816 ? 27.136 55.979 -11.369 1.00 6.75 ? 816 ARG A CZ 1 ATOM 6480 N NH1 . ARG A 1 816 ? 26.445 55.042 -10.723 1.00 7.44 ? 816 ARG A NH1 1 ATOM 6481 N NH2 . ARG A 1 816 ? 28.185 56.554 -10.750 1.00 7.61 ? 816 ARG A NH2 1 ATOM 6482 N N . ARG A 1 817 ? 21.241 54.373 -15.091 1.00 7.39 ? 817 ARG A N 1 ATOM 6483 C CA . ARG A 1 817 ? 19.901 54.413 -15.674 1.00 7.05 ? 817 ARG A CA 1 ATOM 6484 C C . ARG A 1 817 ? 19.162 55.558 -14.999 1.00 7.92 ? 817 ARG A C 1 ATOM 6485 O O . ARG A 1 817 ? 19.035 55.612 -13.762 1.00 8.69 ? 817 ARG A O 1 ATOM 6486 C CB . ARG A 1 817 ? 19.174 53.047 -15.432 1.00 8.75 ? 817 ARG A CB 1 ATOM 6487 C CG . ARG A 1 817 ? 17.718 53.109 -15.922 1.00 10.44 ? 817 ARG A CG 1 ATOM 6488 C CD . ARG A 1 817 ? 16.974 51.737 -15.723 1.00 11.04 ? 817 ARG A CD 1 ATOM 6489 N NE . ARG A 1 817 ? 17.555 50.707 -16.561 1.00 11.84 ? 817 ARG A NE 1 ATOM 6490 C CZ . ARG A 1 817 ? 18.286 49.672 -16.147 1.00 14.41 ? 817 ARG A CZ 1 ATOM 6491 N NH1 . ARG A 1 817 ? 18.554 49.534 -14.867 1.00 13.64 ? 817 ARG A NH1 1 ATOM 6492 N NH2 . ARG A 1 817 ? 18.734 48.757 -16.997 1.00 16.96 ? 817 ARG A NH2 1 ATOM 6493 N N . ARG A 1 818 ? 18.687 56.501 -15.815 1.00 7.36 ? 818 ARG A N 1 ATOM 6494 C CA . ARG A 1 818 ? 17.902 57.611 -15.313 1.00 8.99 ? 818 ARG A CA 1 ATOM 6495 C C . ARG A 1 818 ? 16.589 57.016 -14.761 1.00 10.68 ? 818 ARG A C 1 ATOM 6496 O O . ARG A 1 818 ? 15.951 56.222 -15.453 1.00 11.29 ? 818 ARG A O 1 ATOM 6497 C CB . ARG A 1 818 ? 17.595 58.565 -16.481 1.00 8.48 ? 818 ARG A CB 1 ATOM 6498 C CG A ARG A 1 818 ? 16.971 59.873 -16.018 0.50 9.75 ? 818 ARG A CG 1 ATOM 6499 C CG B ARG A 1 818 ? 16.669 59.750 -15.998 0.50 10.35 ? 818 ARG A CG 1 ATOM 6500 C CD . ARG A 1 818 ? 16.227 60.607 -17.178 1.00 10.32 ? 818 ARG A CD 1 ATOM 6501 N NE A ARG A 1 818 ? 14.967 59.914 -17.517 0.50 14.40 ? 818 ARG A NE 1 ATOM 6502 N NE B ARG A 1 818 ? 17.150 60.571 -18.253 0.50 27.14 ? 818 ARG A NE 1 ATOM 6503 C CZ A ARG A 1 818 ? 14.679 59.335 -18.685 0.50 13.86 ? 818 ARG A CZ 1 ATOM 6504 C CZ B ARG A 1 818 ? 16.985 59.977 -19.434 0.50 28.20 ? 818 ARG A CZ 1 ATOM 6505 N NH1 A ARG A 1 818 ? 15.536 59.318 -19.708 0.50 12.91 ? 818 ARG A NH1 1 ATOM 6506 N NH1 B ARG A 1 818 ? 15.829 59.390 -19.768 0.50 26.34 ? 818 ARG A NH1 1 ATOM 6507 N NH2 A ARG A 1 818 ? 13.476 58.760 -18.838 0.50 15.43 ? 818 ARG A NH2 1 ATOM 6508 N NH2 B ARG A 1 818 ? 18.038 59.857 -20.229 0.50 26.62 ? 818 ARG A NH2 1 ATOM 6509 N N . LEU A 1 819 ? 16.211 57.388 -13.542 1.00 8.98 ? 819 LEU A N 1 ATOM 6510 C CA . LEU A 1 819 ? 14.986 56.873 -12.889 1.00 10.60 ? 819 LEU A CA 1 ATOM 6511 C C . LEU A 1 819 ? 14.009 57.994 -12.633 1.00 9.35 ? 819 LEU A C 1 ATOM 6512 O O . LEU A 1 819 ? 14.259 58.869 -11.816 1.00 10.58 ? 819 LEU A O 1 ATOM 6513 C CB . LEU A 1 819 ? 15.355 56.193 -11.564 1.00 11.80 ? 819 LEU A CB 1 ATOM 6514 C CG . LEU A 1 819 ? 16.265 54.927 -11.732 1.00 11.98 ? 819 LEU A CG 1 ATOM 6515 C CD1 . LEU A 1 819 ? 16.759 54.469 -10.316 1.00 14.11 ? 819 LEU A CD1 1 ATOM 6516 C CD2 . LEU A 1 819 ? 15.648 53.795 -12.495 1.00 14.13 ? 819 LEU A CD2 1 ATOM 6517 N N . ASP A 1 820 ? 12.887 57.948 -13.361 1.00 11.26 ? 820 ASP A N 1 ATOM 6518 C CA . ASP A 1 820 ? 11.920 59.003 -13.148 1.00 12.88 ? 820 ASP A CA 1 ATOM 6519 C C . ASP A 1 820 ? 11.186 58.869 -11.818 1.00 11.00 ? 820 ASP A C 1 ATOM 6520 O O . ASP A 1 820 ? 10.551 59.824 -11.405 1.00 13.96 ? 820 ASP A O 1 ATOM 6521 C CB . ASP A 1 820 ? 10.990 59.115 -14.367 1.00 15.50 ? 820 ASP A CB 1 ATOM 6522 C CG . ASP A 1 820 ? 11.776 59.404 -15.668 1.00 18.32 ? 820 ASP A CG 1 ATOM 6523 O OD1 . ASP A 1 820 ? 12.853 60.059 -15.648 1.00 17.45 ? 820 ASP A OD1 1 ATOM 6524 O OD2 . ASP A 1 820 ? 11.334 58.978 -16.747 1.00 22.16 ? 820 ASP A OD2 1 ATOM 6525 N N . LYS A 1 821 ? 11.343 57.734 -11.112 1.00 12.04 ? 821 LYS A N 1 ATOM 6526 C CA . LYS A 1 821 ? 10.761 57.618 -9.777 1.00 12.05 ? 821 LYS A CA 1 ATOM 6527 C C . LYS A 1 821 ? 11.600 58.399 -8.736 1.00 12.88 ? 821 LYS A C 1 ATOM 6528 O O . LYS A 1 821 ? 11.126 58.625 -7.601 1.00 14.84 ? 821 LYS A O 1 ATOM 6529 C CB . LYS A 1 821 ? 10.659 56.138 -9.397 1.00 11.20 ? 821 LYS A CB 1 ATOM 6530 C CG . LYS A 1 821 ? 11.990 55.423 -9.165 1.00 11.19 ? 821 LYS A CG 1 ATOM 6531 C CD . LYS A 1 821 ? 11.803 53.931 -9.055 1.00 11.20 ? 821 LYS A CD 1 ATOM 6532 C CE . LYS A 1 821 ? 13.146 53.228 -8.963 1.00 13.77 ? 821 LYS A CE 1 ATOM 6533 N NZ . LYS A 1 821 ? 13.071 51.759 -9.138 1.00 13.34 ? 821 LYS A NZ 1 ATOM 6534 N N . LEU A 1 822 ? 12.791 58.878 -9.153 1.00 11.62 ? 822 LEU A N 1 ATOM 6535 C CA . LEU A 1 822 ? 13.659 59.672 -8.242 1.00 12.20 ? 822 LEU A CA 1 ATOM 6536 C C . LEU A 1 822 ? 13.677 61.119 -8.767 1.00 11.79 ? 822 LEU A C 1 ATOM 6537 O O . LEU A 1 822 ? 13.487 61.345 -9.968 1.00 11.98 ? 822 LEU A O 1 ATOM 6538 C CB . LEU A 1 822 ? 15.083 59.141 -8.255 1.00 12.13 ? 822 LEU A CB 1 ATOM 6539 C CG . LEU A 1 822 ? 15.230 57.674 -7.752 1.00 12.11 ? 822 LEU A CG 1 ATOM 6540 C CD1 . LEU A 1 822 ? 16.690 57.302 -7.671 1.00 15.09 ? 822 LEU A CD1 1 ATOM 6541 C CD2 . LEU A 1 822 ? 14.515 57.453 -6.395 1.00 13.33 ? 822 LEU A CD2 1 ATOM 6542 N N . PRO A 1 823 ? 13.905 62.093 -7.893 1.00 11.02 ? 823 PRO A N 1 ATOM 6543 C CA . PRO A 1 823 ? 13.943 63.503 -8.335 1.00 10.48 ? 823 PRO A CA 1 ATOM 6544 C C . PRO A 1 823 ? 15.186 63.779 -9.211 1.00 9.91 ? 823 PRO A C 1 ATOM 6545 O O . PRO A 1 823 ? 16.180 63.007 -9.223 1.00 10.46 ? 823 PRO A O 1 ATOM 6546 C CB . PRO A 1 823 ? 13.918 64.286 -7.041 1.00 13.43 ? 823 PRO A CB 1 ATOM 6547 C CG . PRO A 1 823 ? 14.585 63.364 -6.030 1.00 13.34 ? 823 PRO A CG 1 ATOM 6548 C CD . PRO A 1 823 ? 14.052 61.952 -6.434 1.00 11.51 ? 823 PRO A CD 1 ATOM 6549 N N . LEU A 1 824 ? 15.141 64.915 -9.916 1.00 9.71 ? 824 LEU A N 1 ATOM 6550 C CA . LEU A 1 824 ? 16.195 65.299 -10.829 1.00 9.97 ? 824 LEU A CA 1 ATOM 6551 C C . LEU A 1 824 ? 17.611 65.177 -10.200 1.00 8.96 ? 824 LEU A C 1 ATOM 6552 O O . LEU A 1 824 ? 18.496 64.585 -10.805 1.00 8.31 ? 824 LEU A O 1 ATOM 6553 C CB . LEU A 1 824 ? 15.886 66.740 -11.262 1.00 11.88 ? 824 LEU A CB 1 ATOM 6554 C CG . LEU A 1 824 ? 16.683 67.340 -12.384 1.00 10.40 ? 824 LEU A CG 1 ATOM 6555 C CD1 . LEU A 1 824 ? 15.915 68.586 -12.889 1.00 11.48 ? 824 LEU A CD1 1 ATOM 6556 C CD2 . LEU A 1 824 ? 18.134 67.766 -11.922 1.00 8.79 ? 824 LEU A CD2 1 ATOM 6557 N N . GLN A 1 825 ? 17.747 65.720 -8.989 1.00 8.27 ? 825 GLN A N 1 ATOM 6558 C CA . GLN A 1 825 ? 19.068 65.736 -8.320 1.00 7.49 ? 825 GLN A CA 1 ATOM 6559 C C . GLN A 1 825 ? 19.610 64.342 -8.009 1.00 7.48 ? 825 GLN A C 1 ATOM 6560 O O . GLN A 1 825 ? 20.864 64.197 -7.832 1.00 7.95 ? 825 GLN A O 1 ATOM 6561 C CB . GLN A 1 825 ? 19.050 66.606 -7.076 1.00 8.57 ? 825 GLN A CB 1 ATOM 6562 C CG . GLN A 1 825 ? 18.126 66.107 -5.966 1.00 8.15 ? 825 GLN A CG 1 ATOM 6563 C CD . GLN A 1 825 ? 16.664 66.581 -6.067 1.00 9.82 ? 825 GLN A CD 1 ATOM 6564 O OE1 . GLN A 1 825 ? 16.228 67.052 -7.132 1.00 10.29 ? 825 GLN A OE1 1 ATOM 6565 N NE2 . GLN A 1 825 ? 15.933 66.485 -4.967 1.00 8.57 ? 825 GLN A NE2 1 ATOM 6566 N N . ALA A 1 826 ? 18.732 63.316 -7.896 1.00 7.73 ? 826 ALA A N 1 ATOM 6567 C CA . ALA A 1 826 ? 19.200 61.950 -7.649 1.00 7.51 ? 826 ALA A CA 1 ATOM 6568 C C . ALA A 1 826 ? 19.769 61.359 -8.920 1.00 7.13 ? 826 ALA A C 1 ATOM 6569 O O . ALA A 1 826 ? 20.514 60.361 -8.870 1.00 8.95 ? 826 ALA A O 1 ATOM 6570 C CB . ALA A 1 826 ? 17.970 61.114 -7.180 1.00 9.39 ? 826 ALA A CB 1 ATOM 6571 N N . ASN A 1 827 ? 19.433 61.907 -10.107 1.00 7.76 ? 827 ASN A N 1 ATOM 6572 C CA . ASN A 1 827 ? 19.926 61.393 -11.383 1.00 7.85 ? 827 ASN A CA 1 ATOM 6573 C C . ASN A 1 827 ? 21.243 62.044 -11.816 1.00 7.15 ? 827 ASN A C 1 ATOM 6574 O O . ASN A 1 827 ? 21.743 61.739 -12.863 1.00 8.29 ? 827 ASN A O 1 ATOM 6575 C CB . ASN A 1 827 ? 18.807 61.560 -12.456 1.00 8.53 ? 827 ASN A CB 1 ATOM 6576 C CG . ASN A 1 827 ? 17.684 60.552 -12.214 1.00 9.69 ? 827 ASN A CG 1 ATOM 6577 O OD1 . ASN A 1 827 ? 17.926 59.361 -12.278 1.00 9.90 ? 827 ASN A OD1 1 ATOM 6578 N ND2 . ASN A 1 827 ? 16.475 60.999 -11.881 1.00 12.64 ? 827 ASN A ND2 1 ATOM 6579 N N . TYR A 1 828 ? 21.741 62.958 -10.987 1.00 7.88 ? 828 TYR A N 1 ATOM 6580 C CA . TYR A 1 828 ? 23.095 63.507 -11.127 1.00 6.95 ? 828 TYR A CA 1 ATOM 6581 C C . TYR A 1 828 ? 24.135 62.576 -10.492 1.00 6.84 ? 828 TYR A C 1 ATOM 6582 O O . TYR A 1 828 ? 23.937 62.072 -9.402 1.00 8.43 ? 828 TYR A O 1 ATOM 6583 C CB . TYR A 1 828 ? 23.157 64.909 -10.480 1.00 7.21 ? 828 TYR A CB 1 ATOM 6584 C CG . TYR A 1 828 ? 23.181 66.052 -11.488 1.00 6.53 ? 828 TYR A CG 1 ATOM 6585 C CD1 . TYR A 1 828 ? 22.132 66.274 -12.369 1.00 7.91 ? 828 TYR A CD1 1 ATOM 6586 C CD2 . TYR A 1 828 ? 24.259 66.906 -11.549 1.00 8.03 ? 828 TYR A CD2 1 ATOM 6587 C CE1 . TYR A 1 828 ? 22.178 67.301 -13.285 1.00 9.04 ? 828 TYR A CE1 1 ATOM 6588 C CE2 . TYR A 1 828 ? 24.304 67.939 -12.454 1.00 9.03 ? 828 TYR A CE2 1 ATOM 6589 C CZ . TYR A 1 828 ? 23.269 68.129 -13.314 1.00 7.25 ? 828 TYR A CZ 1 ATOM 6590 O OH . TYR A 1 828 ? 23.357 69.142 -14.211 1.00 9.31 ? 828 TYR A OH 1 ATOM 6591 N N . TYR A 1 829 ? 25.247 62.399 -11.198 1.00 6.71 ? 829 TYR A N 1 ATOM 6592 C CA . TYR A 1 829 ? 26.332 61.547 -10.748 1.00 6.54 ? 829 TYR A CA 1 ATOM 6593 C C . TYR A 1 829 ? 27.642 62.271 -10.914 1.00 7.50 ? 829 TYR A C 1 ATOM 6594 O O . TYR A 1 829 ? 27.730 63.279 -11.607 1.00 7.03 ? 829 TYR A O 1 ATOM 6595 C CB . TYR A 1 829 ? 26.363 60.285 -11.628 1.00 6.61 ? 829 TYR A CB 1 ATOM 6596 C CG . TYR A 1 829 ? 25.186 59.361 -11.346 1.00 7.24 ? 829 TYR A CG 1 ATOM 6597 C CD1 . TYR A 1 829 ? 25.214 58.469 -10.289 1.00 6.46 ? 829 TYR A CD1 1 ATOM 6598 C CD2 . TYR A 1 829 ? 24.029 59.418 -12.152 1.00 7.76 ? 829 TYR A CD2 1 ATOM 6599 C CE1 . TYR A 1 829 ? 24.141 57.651 -10.011 1.00 7.62 ? 829 TYR A CE1 1 ATOM 6600 C CE2 . TYR A 1 829 ? 22.945 58.594 -11.870 1.00 8.26 ? 829 TYR A CE2 1 ATOM 6601 C CZ . TYR A 1 829 ? 23.003 57.716 -10.796 1.00 7.11 ? 829 TYR A CZ 1 ATOM 6602 O OH . TYR A 1 829 ? 21.915 56.897 -10.480 1.00 9.21 ? 829 TYR A OH 1 ATOM 6603 N N . PRO A 1 830 ? 28.713 61.795 -10.231 1.00 6.81 ? 830 PRO A N 1 ATOM 6604 C CA . PRO A 1 830 ? 29.999 62.457 -10.419 1.00 7.12 ? 830 PRO A CA 1 ATOM 6605 C C . PRO A 1 830 ? 30.460 62.169 -11.847 1.00 7.44 ? 830 PRO A C 1 ATOM 6606 O O . PRO A 1 830 ? 30.255 61.066 -12.428 1.00 7.62 ? 830 PRO A O 1 ATOM 6607 C CB . PRO A 1 830 ? 30.940 61.769 -9.398 1.00 10.83 ? 830 PRO A CB 1 ATOM 6608 C CG . PRO A 1 830 ? 30.048 60.821 -8.573 1.00 10.68 ? 830 PRO A CG 1 ATOM 6609 C CD . PRO A 1 830 ? 28.726 60.655 -9.289 1.00 6.98 ? 830 PRO A CD 1 ATOM 6610 N N . ILE A 1 831 ? 31.114 63.156 -12.454 1.00 6.09 ? 831 ILE A N 1 ATOM 6611 C CA . ILE A 1 831 ? 31.754 63.018 -13.784 1.00 6.53 ? 831 ILE A CA 1 ATOM 6612 C C . ILE A 1 831 ? 33.224 63.321 -13.504 1.00 6.87 ? 831 ILE A C 1 ATOM 6613 O O . ILE A 1 831 ? 33.723 64.410 -13.832 1.00 7.08 ? 831 ILE A O 1 ATOM 6614 C CB . ILE A 1 831 ? 31.180 63.986 -14.842 1.00 6.39 ? 831 ILE A CB 1 ATOM 6615 C CG1 . ILE A 1 831 ? 29.657 64.041 -14.821 1.00 6.51 ? 831 ILE A CG1 1 ATOM 6616 C CG2 . ILE A 1 831 ? 31.739 63.545 -16.225 1.00 6.94 ? 831 ILE A CG2 1 ATOM 6617 C CD1 . ILE A 1 831 ? 28.909 62.683 -15.116 1.00 6.72 ? 831 ILE A CD1 1 ATOM 6618 N N . PRO A 1 832 ? 33.955 62.370 -12.899 1.00 6.12 ? 832 PRO A N 1 ATOM 6619 C CA . PRO A 1 832 ? 35.353 62.663 -12.591 1.00 6.83 ? 832 PRO A CA 1 ATOM 6620 C C . PRO A 1 832 ? 36.221 62.796 -13.777 1.00 8.13 ? 832 PRO A C 1 ATOM 6621 O O . PRO A 1 832 ? 37.192 63.553 -13.646 1.00 10.67 ? 832 PRO A O 1 ATOM 6622 C CB . PRO A 1 832 ? 35.782 61.547 -11.588 1.00 6.34 ? 832 PRO A CB 1 ATOM 6623 C CG . PRO A 1 832 ? 34.711 60.507 -11.762 1.00 8.94 ? 832 PRO A CG 1 ATOM 6624 C CD . PRO A 1 832 ? 33.442 61.138 -12.252 1.00 6.85 ? 832 PRO A CD 1 ATOM 6625 N N . SER A 1 833 ? 35.928 62.137 -14.895 1.00 6.81 ? 833 SER A N 1 ATOM 6626 C CA . SER A 1 833 ? 36.746 62.250 -16.103 1.00 6.87 ? 833 SER A CA 1 ATOM 6627 C C . SER A 1 833 ? 35.965 62.079 -17.420 1.00 6.29 ? 833 SER A C 1 ATOM 6628 O O . SER A 1 833 ? 36.506 62.428 -18.471 1.00 5.98 ? 833 SER A O 1 ATOM 6629 C CB . SER A 1 833 ? 37.946 61.330 -16.101 1.00 10.55 ? 833 SER A CB 1 ATOM 6630 O OG . SER A 1 833 ? 37.603 60.046 -16.364 1.00 12.23 ? 833 SER A OG 1 ATOM 6631 N N . GLY A 1 834 ? 34.741 61.550 -17.389 1.00 6.56 ? 834 GLY A N 1 ATOM 6632 C CA . GLY A 1 834 ? 34.025 61.465 -18.666 1.00 5.88 ? 834 GLY A CA 1 ATOM 6633 C C . GLY A 1 834 ? 32.678 60.837 -18.532 1.00 5.85 ? 834 GLY A C 1 ATOM 6634 O O . GLY A 1 834 ? 32.284 60.281 -17.501 1.00 6.77 ? 834 GLY A O 1 ATOM 6635 N N . MET A 1 835 ? 31.901 61.007 -19.606 1.00 6.08 ? 835 MET A N 1 ATOM 6636 C CA . MET A 1 835 ? 30.537 60.461 -19.669 1.00 6.46 ? 835 MET A CA 1 ATOM 6637 C C . MET A 1 835 ? 30.183 60.241 -21.127 1.00 5.34 ? 835 MET A C 1 ATOM 6638 O O . MET A 1 835 ? 30.764 60.879 -22.022 1.00 6.42 ? 835 MET A O 1 ATOM 6639 C CB . MET A 1 835 ? 29.535 61.431 -19.016 1.00 6.84 ? 835 MET A CB 1 ATOM 6640 C CG . MET A 1 835 ? 29.444 62.791 -19.788 1.00 7.49 ? 835 MET A CG 1 ATOM 6641 S SD . MET A 1 835 ? 28.572 64.089 -18.890 1.00 10.78 ? 835 MET A SD 1 ATOM 6642 C CE . MET A 1 835 ? 27.046 63.381 -18.397 1.00 12.95 ? 835 MET A CE 1 ATOM 6643 N N . PHE A 1 836 ? 29.228 59.327 -21.373 1.00 6.23 ? 836 PHE A N 1 ATOM 6644 C CA . PHE A 1 836 ? 28.784 59.124 -22.758 1.00 6.02 ? 836 PHE A CA 1 ATOM 6645 C C . PHE A 1 836 ? 27.397 58.585 -22.802 1.00 7.16 ? 836 PHE A C 1 ATOM 6646 O O . PHE A 1 836 ? 26.856 58.017 -21.844 1.00 7.01 ? 836 PHE A O 1 ATOM 6647 C CB . PHE A 1 836 ? 29.767 58.235 -23.580 1.00 7.14 ? 836 PHE A CB 1 ATOM 6648 C CG . PHE A 1 836 ? 29.961 56.797 -23.130 1.00 7.69 ? 836 PHE A CG 1 ATOM 6649 C CD1 . PHE A 1 836 ? 29.105 55.765 -23.601 1.00 7.78 ? 836 PHE A CD1 1 ATOM 6650 C CD2 . PHE A 1 836 ? 31.069 56.444 -22.317 1.00 8.78 ? 836 PHE A CD2 1 ATOM 6651 C CE1 . PHE A 1 836 ? 29.367 54.420 -23.252 1.00 9.86 ? 836 PHE A CE1 1 ATOM 6652 C CE2 . PHE A 1 836 ? 31.316 55.110 -21.996 1.00 8.43 ? 836 PHE A CE2 1 ATOM 6653 C CZ . PHE A 1 836 ? 30.474 54.113 -22.464 1.00 10.42 ? 836 PHE A CZ 1 ATOM 6654 N N . ILE A 1 837 ? 26.788 58.801 -23.980 1.00 6.69 ? 837 ILE A N 1 ATOM 6655 C CA . ILE A 1 837 ? 25.480 58.197 -24.365 1.00 7.45 ? 837 ILE A CA 1 ATOM 6656 C C . ILE A 1 837 ? 25.680 57.541 -25.704 1.00 7.42 ? 837 ILE A C 1 ATOM 6657 O O . ILE A 1 837 ? 26.539 57.938 -26.519 1.00 7.30 ? 837 ILE A O 1 ATOM 6658 C CB . ILE A 1 837 ? 24.331 59.232 -24.425 1.00 8.16 ? 837 ILE A CB 1 ATOM 6659 C CG1 . ILE A 1 837 ? 24.741 60.448 -25.235 1.00 7.71 ? 837 ILE A CG1 1 ATOM 6660 C CG2 . ILE A 1 837 ? 23.840 59.557 -23.042 1.00 8.64 ? 837 ILE A CG2 1 ATOM 6661 C CD1 . ILE A 1 837 ? 23.508 61.323 -25.710 1.00 10.16 ? 837 ILE A CD1 1 ATOM 6662 N N . GLU A 1 838 ? 24.884 56.476 -25.934 1.00 7.06 ? 838 GLU A N 1 ATOM 6663 C CA . GLU A 1 838 ? 24.980 55.795 -27.217 1.00 7.19 ? 838 GLU A CA 1 ATOM 6664 C C . GLU A 1 838 ? 23.668 55.042 -27.540 1.00 7.28 ? 838 GLU A C 1 ATOM 6665 O O . GLU A 1 838 ? 22.815 54.811 -26.694 1.00 8.50 ? 838 GLU A O 1 ATOM 6666 C CB . GLU A 1 838 ? 26.122 54.755 -27.250 1.00 8.34 ? 838 GLU A CB 1 ATOM 6667 C CG . GLU A 1 838 ? 25.906 53.610 -26.262 1.00 10.31 ? 838 GLU A CG 1 ATOM 6668 C CD . GLU A 1 838 ? 27.054 52.600 -26.217 1.00 10.43 ? 838 GLU A CD 1 ATOM 6669 O OE1 . GLU A 1 838 ? 28.048 52.706 -26.931 1.00 12.79 ? 838 GLU A OE1 1 ATOM 6670 O OE2 . GLU A 1 838 ? 26.866 51.607 -25.448 1.00 13.60 ? 838 GLU A OE2 1 ATOM 6671 N N . ASP A 1 839 ? 23.532 54.793 -28.846 1.00 8.61 ? 839 ASP A N 1 ATOM 6672 C CA . ASP A 1 839 ? 22.460 53.876 -29.304 1.00 8.27 ? 839 ASP A CA 1 ATOM 6673 C C . ASP A 1 839 ? 23.187 52.774 -30.098 1.00 9.30 ? 839 ASP A C 1 ATOM 6674 O O . ASP A 1 839 ? 24.372 52.570 -29.983 1.00 11.23 ? 839 ASP A O 1 ATOM 6675 C CB . ASP A 1 839 ? 21.343 54.604 -30.099 1.00 9.26 ? 839 ASP A CB 1 ATOM 6676 C CG . ASP A 1 839 ? 21.810 55.334 -31.345 1.00 10.87 ? 839 ASP A CG 1 ATOM 6677 O OD1 . ASP A 1 839 ? 22.826 54.992 -31.932 1.00 11.00 ? 839 ASP A OD1 1 ATOM 6678 O OD2 . ASP A 1 839 ? 21.061 56.316 -31.733 1.00 14.73 ? 839 ASP A OD2 1 ATOM 6679 N N . ALA A 1 840 ? 22.429 52.055 -30.945 1.00 11.61 ? 840 ALA A N 1 ATOM 6680 C CA . ALA A 1 840 ? 23.066 50.981 -31.687 1.00 12.61 ? 840 ALA A CA 1 ATOM 6681 C C . ALA A 1 840 ? 24.152 51.445 -32.621 1.00 11.61 ? 840 ALA A C 1 ATOM 6682 O O . ALA A 1 840 ? 25.129 50.720 -32.851 1.00 14.13 ? 840 ALA A O 1 ATOM 6683 C CB . ALA A 1 840 ? 22.023 50.198 -32.478 1.00 13.91 ? 840 ALA A CB 1 ATOM 6684 N N . ASN A 1 841 ? 24.028 52.689 -33.114 1.00 10.87 ? 841 ASN A N 1 ATOM 6685 C CA . ASN A 1 841 ? 24.982 53.160 -34.120 1.00 9.94 ? 841 ASN A CA 1 ATOM 6686 C C . ASN A 1 841 ? 25.966 54.260 -33.801 1.00 8.96 ? 841 ASN A C 1 ATOM 6687 O O . ASN A 1 841 ? 26.990 54.340 -34.431 1.00 10.52 ? 841 ASN A O 1 ATOM 6688 C CB . ASN A 1 841 ? 24.178 53.579 -35.408 1.00 12.22 ? 841 ASN A CB 1 ATOM 6689 C CG . ASN A 1 841 ? 23.430 52.368 -36.003 1.00 13.44 ? 841 ASN A CG 1 ATOM 6690 O OD1 . ASN A 1 841 ? 24.010 51.308 -36.124 1.00 17.33 ? 841 ASN A OD1 1 ATOM 6691 N ND2 . ASN A 1 841 ? 22.158 52.530 -36.260 1.00 20.60 ? 841 ASN A ND2 1 ATOM 6692 N N . THR A 1 842 ? 25.559 55.108 -32.873 1.00 9.14 ? 842 THR A N 1 ATOM 6693 C CA . THR A 1 842 ? 26.270 56.341 -32.567 1.00 8.82 ? 842 THR A CA 1 ATOM 6694 C C . THR A 1 842 ? 26.506 56.518 -31.074 1.00 8.10 ? 842 THR A C 1 ATOM 6695 O O . THR A 1 842 ? 25.623 56.263 -30.257 1.00 9.21 ? 842 THR A O 1 ATOM 6696 C CB . THR A 1 842 ? 25.398 57.551 -33.055 1.00 9.59 ? 842 THR A CB 1 ATOM 6697 O OG1 . THR A 1 842 ? 25.014 57.326 -34.458 1.00 12.28 ? 842 THR A OG1 1 ATOM 6698 C CG2 . THR A 1 842 ? 26.156 58.856 -33.057 1.00 11.12 ? 842 THR A CG2 1 ATOM 6699 N N . ARG A 1 843 ? 27.680 57.074 -30.793 1.00 7.48 ? 843 ARG A N 1 ATOM 6700 C CA . ARG A 1 843 ? 28.053 57.421 -29.398 1.00 7.74 ? 843 ARG A CA 1 ATOM 6701 C C . ARG A 1 843 ? 28.589 58.866 -29.332 1.00 7.08 ? 843 ARG A C 1 ATOM 6702 O O . ARG A 1 843 ? 29.276 59.309 -30.272 1.00 7.81 ? 843 ARG A O 1 ATOM 6703 C CB . ARG A 1 843 ? 29.114 56.458 -28.879 1.00 7.85 ? 843 ARG A CB 1 ATOM 6704 C CG . ARG A 1 843 ? 29.547 56.749 -27.422 1.00 7.92 ? 843 ARG A CG 1 ATOM 6705 C CD . ARG A 1 843 ? 30.707 55.901 -26.942 1.00 6.98 ? 843 ARG A CD 1 ATOM 6706 N NE . ARG A 1 843 ? 30.301 54.513 -26.706 1.00 7.97 ? 843 ARG A NE 1 ATOM 6707 C CZ . ARG A 1 843 ? 31.112 53.670 -26.108 1.00 8.39 ? 843 ARG A CZ 1 ATOM 6708 N NH1 . ARG A 1 843 ? 32.334 54.007 -25.731 1.00 8.02 ? 843 ARG A NH1 1 ATOM 6709 N NH2 . ARG A 1 843 ? 30.651 52.454 -25.773 1.00 8.52 ? 843 ARG A NH2 1 ATOM 6710 N N . LEU A 1 844 ? 28.218 59.565 -28.274 1.00 7.32 ? 844 LEU A N 1 ATOM 6711 C CA . LEU A 1 844 ? 28.809 60.884 -27.997 1.00 6.50 ? 844 LEU A CA 1 ATOM 6712 C C . LEU A 1 844 ? 29.457 60.784 -26.597 1.00 6.69 ? 844 LEU A C 1 ATOM 6713 O O . LEU A 1 844 ? 28.759 60.479 -25.625 1.00 6.86 ? 844 LEU A O 1 ATOM 6714 C CB . LEU A 1 844 ? 27.761 62.005 -28.019 1.00 8.21 ? 844 LEU A CB 1 ATOM 6715 C CG . LEU A 1 844 ? 28.398 63.409 -27.881 1.00 8.56 ? 844 LEU A CG 1 ATOM 6716 C CD1 . LEU A 1 844 ? 29.253 63.729 -29.105 1.00 11.05 ? 844 LEU A CD1 1 ATOM 6717 C CD2 . LEU A 1 844 ? 27.285 64.426 -27.727 1.00 11.64 ? 844 LEU A CD2 1 ATOM 6718 N N . THR A 1 845 ? 30.770 61.014 -26.584 1.00 6.83 ? 845 THR A N 1 ATOM 6719 C CA . THR A 1 845 ? 31.532 60.965 -25.310 1.00 6.53 ? 845 THR A CA 1 ATOM 6720 C C . THR A 1 845 ? 32.082 62.387 -25.033 1.00 7.20 ? 845 THR A C 1 ATOM 6721 O O . THR A 1 845 ? 32.685 63.010 -25.919 1.00 7.55 ? 845 THR A O 1 ATOM 6722 C CB . THR A 1 845 ? 32.738 60.020 -25.428 1.00 7.19 ? 845 THR A CB 1 ATOM 6723 O OG1 . THR A 1 845 ? 32.273 58.711 -25.829 1.00 7.85 ? 845 THR A OG1 1 ATOM 6724 C CG2 . THR A 1 845 ? 33.457 59.840 -24.094 1.00 7.39 ? 845 THR A CG2 1 ATOM 6725 N N . LEU A 1 846 ? 31.897 62.838 -23.800 1.00 6.77 ? 846 LEU A N 1 ATOM 6726 C CA . LEU A 1 846 ? 32.450 64.116 -23.337 1.00 5.81 ? 846 LEU A CA 1 ATOM 6727 C C . LEU A 1 846 ? 33.520 63.769 -22.280 1.00 5.80 ? 846 LEU A C 1 ATOM 6728 O O . LEU A 1 846 ? 33.152 63.164 -21.225 1.00 6.56 ? 846 LEU A O 1 ATOM 6729 C CB . LEU A 1 846 ? 31.363 65.004 -22.733 1.00 8.15 ? 846 LEU A CB 1 ATOM 6730 C CG . LEU A 1 846 ? 31.865 66.371 -22.233 1.00 8.02 ? 846 LEU A CG 1 ATOM 6731 C CD1 . LEU A 1 846 ? 32.277 67.272 -23.393 1.00 9.14 ? 846 LEU A CD1 1 ATOM 6732 C CD2 . LEU A 1 846 ? 30.775 67.072 -21.422 1.00 14.08 ? 846 LEU A CD2 1 ATOM 6733 N N . LEU A 1 847 ? 34.789 64.049 -22.547 1.00 5.71 ? 847 LEU A N 1 ATOM 6734 C CA . LEU A 1 847 ? 35.886 63.815 -21.582 1.00 5.19 ? 847 LEU A CA 1 ATOM 6735 C C . LEU A 1 847 ? 36.133 65.140 -20.866 1.00 5.99 ? 847 LEU A C 1 ATOM 6736 O O . LEU A 1 847 ? 35.997 66.228 -21.464 1.00 6.73 ? 847 LEU A O 1 ATOM 6737 C CB . LEU A 1 847 ? 37.172 63.347 -22.256 1.00 6.77 ? 847 LEU A CB 1 ATOM 6738 C CG . LEU A 1 847 ? 37.127 61.994 -22.969 1.00 6.34 ? 847 LEU A CG 1 ATOM 6739 C CD1 . LEU A 1 847 ? 36.465 60.893 -22.111 1.00 6.96 ? 847 LEU A CD1 1 ATOM 6740 C CD2 . LEU A 1 847 ? 36.424 62.095 -24.370 1.00 7.26 ? 847 LEU A CD2 1 ATOM 6741 N N . THR A 1 848 ? 36.482 65.070 -19.582 1.00 5.85 ? 848 THR A N 1 ATOM 6742 C CA . THR A 1 848 ? 36.708 66.296 -18.777 1.00 6.08 ? 848 THR A CA 1 ATOM 6743 C C . THR A 1 848 ? 38.104 66.369 -18.171 1.00 7.47 ? 848 THR A C 1 ATOM 6744 O O . THR A 1 848 ? 38.776 65.347 -17.914 1.00 8.99 ? 848 THR A O 1 ATOM 6745 C CB . THR A 1 848 ? 35.745 66.399 -17.612 1.00 8.31 ? 848 THR A CB 1 ATOM 6746 O OG1 . THR A 1 848 ? 36.182 65.469 -16.569 1.00 12.85 ? 848 THR A OG1 1 ATOM 6747 C CG2 . THR A 1 848 ? 34.371 66.113 -17.984 1.00 10.33 ? 848 THR A CG2 1 ATOM 6748 N N . GLY A 1 849 ? 38.580 67.604 -18.031 1.00 6.17 ? 849 GLY A N 1 ATOM 6749 C CA . GLY A 1 849 ? 39.849 67.873 -17.368 1.00 5.88 ? 849 GLY A CA 1 ATOM 6750 C C . GLY A 1 849 ? 39.655 68.205 -15.884 1.00 5.28 ? 849 GLY A C 1 ATOM 6751 O O . GLY A 1 849 ? 40.624 68.629 -15.233 1.00 6.21 ? 849 GLY A O 1 ATOM 6752 N N . GLN A 1 850 ? 38.469 68.024 -15.337 1.00 5.19 ? 850 GLN A N 1 ATOM 6753 C CA . GLN A 1 850 ? 38.156 68.333 -13.938 1.00 5.62 ? 850 GLN A CA 1 ATOM 6754 C C . GLN A 1 850 ? 36.892 67.603 -13.556 1.00 6.14 ? 850 GLN A C 1 ATOM 6755 O O . GLN A 1 850 ? 35.987 67.402 -14.395 1.00 6.56 ? 850 GLN A O 1 ATOM 6756 C CB . GLN A 1 850 ? 37.927 69.875 -13.766 1.00 6.38 ? 850 GLN A CB 1 ATOM 6757 C CG . GLN A 1 850 ? 36.803 70.463 -14.702 1.00 5.96 ? 850 GLN A CG 1 ATOM 6758 C CD . GLN A 1 850 ? 37.193 70.567 -16.148 1.00 6.25 ? 850 GLN A CD 1 ATOM 6759 O OE1 . GLN A 1 850 ? 38.310 70.966 -16.530 1.00 6.77 ? 850 GLN A OE1 1 ATOM 6760 N NE2 . GLN A 1 850 ? 36.242 70.203 -17.022 1.00 5.98 ? 850 GLN A NE2 1 ATOM 6761 N N . PRO A 1 851 ? 36.763 67.194 -12.296 1.00 5.54 ? 851 PRO A N 1 ATOM 6762 C CA . PRO A 1 851 ? 35.526 66.487 -11.883 1.00 5.12 ? 851 PRO A CA 1 ATOM 6763 C C . PRO A 1 851 ? 34.427 67.496 -11.684 1.00 5.21 ? 851 PRO A C 1 ATOM 6764 O O . PRO A 1 851 ? 34.622 68.562 -11.051 1.00 6.51 ? 851 PRO A O 1 ATOM 6765 C CB . PRO A 1 851 ? 35.912 65.819 -10.528 1.00 5.89 ? 851 PRO A CB 1 ATOM 6766 C CG . PRO A 1 851 ? 37.040 66.789 -9.973 1.00 5.55 ? 851 PRO A CG 1 ATOM 6767 C CD . PRO A 1 851 ? 37.784 67.247 -11.220 1.00 5.24 ? 851 PRO A CD 1 ATOM 6768 N N . LEU A 1 852 ? 33.241 67.194 -12.234 1.00 5.69 ? 852 LEU A N 1 ATOM 6769 C CA . LEU A 1 852 ? 32.054 68.027 -12.128 1.00 7.18 ? 852 LEU A CA 1 ATOM 6770 C C . LEU A 1 852 ? 30.828 67.108 -12.046 1.00 7.55 ? 852 LEU A C 1 ATOM 6771 O O . LEU A 1 852 ? 30.939 65.909 -12.303 1.00 11.70 ? 852 LEU A O 1 ATOM 6772 C CB . LEU A 1 852 ? 31.937 68.924 -13.389 1.00 7.33 ? 852 LEU A CB 1 ATOM 6773 C CG . LEU A 1 852 ? 33.062 69.957 -13.519 1.00 6.35 ? 852 LEU A CG 1 ATOM 6774 C CD1 . LEU A 1 852 ? 33.033 70.548 -14.976 1.00 7.52 ? 852 LEU A CD1 1 ATOM 6775 C CD2 . LEU A 1 852 ? 32.940 71.068 -12.501 1.00 8.04 ? 852 LEU A CD2 1 ATOM 6776 N N . GLY A 1 853 ? 29.669 67.618 -11.707 1.00 5.75 ? 853 GLY A N 1 ATOM 6777 C CA . GLY A 1 853 ? 28.480 66.800 -11.694 1.00 6.73 ? 853 GLY A CA 1 ATOM 6778 C C . GLY A 1 853 ? 27.730 66.780 -13.004 1.00 6.11 ? 853 GLY A C 1 ATOM 6779 O O . GLY A 1 853 ? 27.775 67.787 -13.749 1.00 6.19 ? 853 GLY A O 1 ATOM 6780 N N . GLY A 1 854 ? 27.043 65.693 -13.310 1.00 5.42 ? 854 GLY A N 1 ATOM 6781 C CA . GLY A 1 854 ? 26.331 65.684 -14.584 1.00 7.02 ? 854 GLY A CA 1 ATOM 6782 C C . GLY A 1 854 ? 25.343 64.558 -14.677 1.00 5.22 ? 854 GLY A C 1 ATOM 6783 O O . GLY A 1 854 ? 25.170 63.729 -13.768 1.00 6.65 ? 854 GLY A O 1 ATOM 6784 N N . SER A 1 855 ? 24.641 64.542 -15.814 1.00 6.86 ? 855 SER A N 1 ATOM 6785 C CA . SER A 1 855 ? 23.586 63.564 -15.995 1.00 7.19 ? 855 SER A CA 1 ATOM 6786 C C . SER A 1 855 ? 23.182 63.527 -17.459 1.00 7.07 ? 855 SER A C 1 ATOM 6787 O O . SER A 1 855 ? 23.708 64.212 -18.339 1.00 7.93 ? 855 SER A O 1 ATOM 6788 C CB . SER A 1 855 ? 22.322 64.021 -15.216 1.00 8.03 ? 855 SER A CB 1 ATOM 6789 O OG . SER A 1 855 ? 21.315 62.980 -15.179 1.00 9.10 ? 855 SER A OG 1 ATOM 6790 N N . SER A 1 856 ? 22.212 62.628 -17.724 1.00 7.49 ? 856 SER A N 1 ATOM 6791 C CA . SER A 1 856 ? 21.476 62.591 -19.030 1.00 7.99 ? 856 SER A CA 1 ATOM 6792 C C . SER A 1 856 ? 20.005 62.614 -18.594 1.00 8.55 ? 856 SER A C 1 ATOM 6793 O O . SER A 1 856 ? 19.458 61.584 -18.182 1.00 9.38 ? 856 SER A O 1 ATOM 6794 C CB . SER A 1 856 ? 21.807 61.341 -19.776 1.00 6.98 ? 856 SER A CB 1 ATOM 6795 O OG . SER A 1 856 ? 20.972 61.279 -20.959 1.00 8.68 ? 856 SER A OG 1 ATOM 6796 N N . LEU A 1 857 ? 19.353 63.773 -18.613 1.00 8.37 ? 857 LEU A N 1 ATOM 6797 C CA . LEU A 1 857 ? 17.981 63.877 -18.097 1.00 7.94 ? 857 LEU A CA 1 ATOM 6798 C C . LEU A 1 857 ? 16.896 63.549 -19.134 1.00 8.79 ? 857 LEU A C 1 ATOM 6799 O O . LEU A 1 857 ? 15.719 63.514 -18.787 1.00 9.18 ? 857 LEU A O 1 ATOM 6800 C CB . LEU A 1 857 ? 17.751 65.304 -17.503 1.00 9.08 ? 857 LEU A CB 1 ATOM 6801 C CG . LEU A 1 857 ? 18.605 65.564 -16.278 1.00 9.71 ? 857 LEU A CG 1 ATOM 6802 C CD1 . LEU A 1 857 ? 18.477 67.066 -15.808 1.00 11.04 ? 857 LEU A CD1 1 ATOM 6803 C CD2 . LEU A 1 857 ? 18.199 64.599 -15.134 1.00 12.19 ? 857 LEU A CD2 1 ATOM 6804 N N . ALA A 1 858 ? 17.313 63.354 -20.368 1.00 7.89 ? 858 ALA A N 1 ATOM 6805 C CA . ALA A 1 858 ? 16.422 62.934 -21.430 1.00 8.25 ? 858 ALA A CA 1 ATOM 6806 C C . ALA A 1 858 ? 17.231 62.218 -22.496 1.00 9.47 ? 858 ALA A C 1 ATOM 6807 O O . ALA A 1 858 ? 18.412 62.481 -22.675 1.00 8.57 ? 858 ALA A O 1 ATOM 6808 C CB . ALA A 1 858 ? 15.697 64.167 -22.040 1.00 9.57 ? 858 ALA A CB 1 ATOM 6809 N N . SER A 1 859 ? 16.567 61.324 -23.215 1.00 9.70 ? 859 SER A N 1 ATOM 6810 C CA . SER A 1 859 ? 17.198 60.617 -24.286 1.00 8.83 ? 859 SER A CA 1 ATOM 6811 C C . SER A 1 859 ? 17.911 61.566 -25.222 1.00 7.60 ? 859 SER A C 1 ATOM 6812 O O . SER A 1 859 ? 17.370 62.645 -25.536 1.00 9.70 ? 859 SER A O 1 ATOM 6813 C CB . SER A 1 859 ? 16.099 59.802 -25.029 1.00 10.65 ? 859 SER A CB 1 ATOM 6814 O OG . SER A 1 859 ? 16.638 59.054 -26.055 1.00 10.32 ? 859 SER A OG 1 ATOM 6815 N N . GLY A 1 860 ? 19.122 61.226 -25.585 1.00 8.01 ? 860 GLY A N 1 ATOM 6816 C CA . GLY A 1 860 ? 19.890 62.050 -26.488 1.00 9.19 ? 860 GLY A CA 1 ATOM 6817 C C . GLY A 1 860 ? 20.666 63.208 -25.830 1.00 7.77 ? 860 GLY A C 1 ATOM 6818 O O . GLY A 1 860 ? 21.434 63.886 -26.530 1.00 8.36 ? 860 GLY A O 1 ATOM 6819 N N . GLU A 1 861 ? 20.520 63.403 -24.516 1.00 7.51 ? 861 GLU A N 1 ATOM 6820 C CA . GLU A 1 861 ? 21.216 64.531 -23.865 1.00 8.20 ? 861 GLU A CA 1 ATOM 6821 C C . GLU A 1 861 ? 22.345 64.145 -22.962 1.00 9.45 ? 861 GLU A C 1 ATOM 6822 O O . GLU A 1 861 ? 22.365 63.023 -22.399 1.00 9.79 ? 861 GLU A O 1 ATOM 6823 C CB . GLU A 1 861 ? 20.279 65.329 -22.969 1.00 11.05 ? 861 GLU A CB 1 ATOM 6824 C CG . GLU A 1 861 ? 19.155 65.938 -23.686 1.00 11.46 ? 861 GLU A CG 1 ATOM 6825 C CD . GLU A 1 861 ? 18.228 66.783 -22.791 1.00 12.95 ? 861 GLU A CD 1 ATOM 6826 O OE1 . GLU A 1 861 ? 18.345 66.864 -21.526 1.00 12.95 ? 861 GLU A OE1 1 ATOM 6827 O OE2 . GLU A 1 861 ? 17.278 67.423 -23.373 1.00 15.99 ? 861 GLU A OE2 1 ATOM 6828 N N . LEU A 1 862 ? 23.289 65.055 -22.828 1.00 8.39 ? 862 LEU A N 1 ATOM 6829 C CA . LEU A 1 862 ? 24.347 64.924 -21.775 1.00 8.68 ? 862 LEU A CA 1 ATOM 6830 C C . LEU A 1 862 ? 24.367 66.314 -21.143 1.00 6.95 ? 862 LEU A C 1 ATOM 6831 O O . LEU A 1 862 ? 24.207 67.330 -21.850 1.00 8.09 ? 862 LEU A O 1 ATOM 6832 C CB . LEU A 1 862 ? 25.748 64.666 -22.381 1.00 9.30 ? 862 LEU A CB 1 ATOM 6833 C CG . LEU A 1 862 ? 26.043 63.308 -22.983 1.00 9.96 ? 862 LEU A CG 1 ATOM 6834 C CD1 . LEU A 1 862 ? 27.373 63.327 -23.704 1.00 11.02 ? 862 LEU A CD1 1 ATOM 6835 C CD2 . LEU A 1 862 ? 26.006 62.254 -21.889 1.00 11.75 ? 862 LEU A CD2 1 ATOM 6836 N N . GLU A 1 863 ? 24.636 66.437 -19.850 1.00 6.38 ? 863 GLU A N 1 ATOM 6837 C CA . GLU A 1 863 ? 24.829 67.772 -19.295 1.00 6.66 ? 863 GLU A CA 1 ATOM 6838 C C . GLU A 1 863 ? 25.822 67.687 -18.152 1.00 7.21 ? 863 GLU A C 1 ATOM 6839 O O . GLU A 1 863 ? 25.951 66.666 -17.474 1.00 6.66 ? 863 GLU A O 1 ATOM 6840 C CB . GLU A 1 863 ? 23.550 68.426 -18.831 1.00 8.20 ? 863 GLU A CB 1 ATOM 6841 C CG . GLU A 1 863 ? 22.922 67.808 -17.580 1.00 8.79 ? 863 GLU A CG 1 ATOM 6842 C CD . GLU A 1 863 ? 21.631 68.538 -17.210 1.00 8.58 ? 863 GLU A CD 1 ATOM 6843 O OE1 . GLU A 1 863 ? 20.695 68.584 -18.088 1.00 9.93 ? 863 GLU A OE1 1 ATOM 6844 O OE2 . GLU A 1 863 ? 21.508 69.099 -16.087 1.00 8.72 ? 863 GLU A OE2 1 ATOM 6845 N N . ILE A 1 864 ? 26.533 68.786 -17.948 1.00 6.50 ? 864 ILE A N 1 ATOM 6846 C CA . ILE A 1 864 ? 27.577 68.837 -16.889 1.00 6.87 ? 864 ILE A CA 1 ATOM 6847 C C . ILE A 1 864 ? 27.587 70.227 -16.285 1.00 6.15 ? 864 ILE A C 1 ATOM 6848 O O . ILE A 1 864 ? 27.609 71.251 -17.030 1.00 6.20 ? 864 ILE A O 1 ATOM 6849 C CB . ILE A 1 864 ? 28.952 68.405 -17.498 1.00 8.48 ? 864 ILE A CB 1 ATOM 6850 C CG1 . ILE A 1 864 ? 30.026 68.334 -16.403 1.00 9.87 ? 864 ILE A CG1 1 ATOM 6851 C CG2 . ILE A 1 864 ? 29.348 69.247 -18.696 1.00 11.04 ? 864 ILE A CG2 1 ATOM 6852 C CD1 . ILE A 1 864 ? 31.143 67.377 -16.926 1.00 9.85 ? 864 ILE A CD1 1 ATOM 6853 N N . MET A 1 865 ? 27.537 70.283 -14.953 1.00 6.50 ? 865 MET A N 1 ATOM 6854 C CA . MET A 1 865 ? 27.479 71.549 -14.243 1.00 6.41 ? 865 MET A CA 1 ATOM 6855 C C . MET A 1 865 ? 28.837 72.233 -14.295 1.00 7.00 ? 865 MET A C 1 ATOM 6856 O O . MET A 1 865 ? 29.893 71.602 -14.121 1.00 8.08 ? 865 MET A O 1 ATOM 6857 C CB . MET A 1 865 ? 27.021 71.287 -12.803 1.00 7.06 ? 865 MET A CB 1 ATOM 6858 C CG . MET A 1 865 ? 26.427 72.562 -12.134 1.00 7.24 ? 865 MET A CG 1 ATOM 6859 S SD . MET A 1 865 ? 24.808 72.994 -12.879 1.00 9.14 ? 865 MET A SD 1 ATOM 6860 C CE . MET A 1 865 ? 23.829 71.731 -11.954 1.00 9.51 ? 865 MET A CE 1 ATOM 6861 N N . GLN A 1 866 ? 28.815 73.564 -14.495 1.00 6.93 ? 866 GLN A N 1 ATOM 6862 C CA . GLN A 1 866 ? 30.043 74.357 -14.613 1.00 6.32 ? 866 GLN A CA 1 ATOM 6863 C C . GLN A 1 866 ? 30.437 75.048 -13.313 1.00 7.10 ? 866 GLN A C 1 ATOM 6864 O O . GLN A 1 866 ? 31.613 75.078 -12.940 1.00 7.59 ? 866 GLN A O 1 ATOM 6865 C CB . GLN A 1 866 ? 29.865 75.415 -15.718 1.00 7.24 ? 866 GLN A CB 1 ATOM 6866 C CG . GLN A 1 866 ? 29.541 74.778 -17.095 1.00 7.72 ? 866 GLN A CG 1 ATOM 6867 C CD . GLN A 1 866 ? 30.581 73.801 -17.518 1.00 6.62 ? 866 GLN A CD 1 ATOM 6868 O OE1 . GLN A 1 866 ? 31.696 74.175 -17.861 1.00 8.50 ? 866 GLN A OE1 1 ATOM 6869 N NE2 . GLN A 1 866 ? 30.233 72.521 -17.490 1.00 8.28 ? 866 GLN A NE2 1 ATOM 6870 N N . ASP A 1 867 ? 29.443 75.686 -12.655 1.00 7.41 ? 867 ASP A N 1 ATOM 6871 C CA . ASP A 1 867 ? 29.673 76.323 -11.349 1.00 6.74 ? 867 ASP A CA 1 ATOM 6872 C C . ASP A 1 867 ? 28.341 76.535 -10.679 1.00 5.94 ? 867 ASP A C 1 ATOM 6873 O O . ASP A 1 867 ? 27.285 76.454 -11.347 1.00 7.42 ? 867 ASP A O 1 ATOM 6874 C CB . ASP A 1 867 ? 30.494 77.652 -11.475 1.00 8.74 ? 867 ASP A CB 1 ATOM 6875 C CG . ASP A 1 867 ? 31.180 78.048 -10.145 1.00 8.05 ? 867 ASP A CG 1 ATOM 6876 O OD1 . ASP A 1 867 ? 31.046 77.367 -9.123 1.00 8.41 ? 867 ASP A OD1 1 ATOM 6877 O OD2 . ASP A 1 867 ? 31.914 79.052 -10.188 1.00 8.64 ? 867 ASP A OD2 1 ATOM 6878 N N . ARG A 1 868 ? 28.372 76.798 -9.388 1.00 7.14 ? 868 ARG A N 1 ATOM 6879 C CA . ARG A 1 868 ? 27.158 77.054 -8.628 1.00 6.96 ? 868 ARG A CA 1 ATOM 6880 C C . ARG A 1 868 ? 27.458 78.063 -7.530 1.00 7.12 ? 868 ARG A C 1 ATOM 6881 O O . ARG A 1 868 ? 28.482 77.983 -6.872 1.00 7.89 ? 868 ARG A O 1 ATOM 6882 C CB . ARG A 1 868 ? 26.622 75.739 -8.037 1.00 7.48 ? 868 ARG A CB 1 ATOM 6883 C CG . ARG A 1 868 ? 27.651 74.925 -7.243 1.00 8.32 ? 868 ARG A CG 1 ATOM 6884 C CD . ARG A 1 868 ? 27.341 73.411 -7.255 1.00 8.10 ? 868 ARG A CD 1 ATOM 6885 N NE . ARG A 1 868 ? 25.979 73.180 -6.781 1.00 6.75 ? 868 ARG A NE 1 ATOM 6886 C CZ . ARG A 1 868 ? 25.662 72.923 -5.520 1.00 6.70 ? 868 ARG A CZ 1 ATOM 6887 N NH1 . ARG A 1 868 ? 26.601 72.821 -4.587 1.00 7.87 ? 868 ARG A NH1 1 ATOM 6888 N NH2 . ARG A 1 868 ? 24.397 72.764 -5.188 1.00 8.16 ? 868 ARG A NH2 1 ATOM 6889 N N . ARG A 1 869 ? 26.555 79.020 -7.353 1.00 8.17 ? 869 ARG A N 1 ATOM 6890 C CA . ARG A 1 869 ? 26.729 80.104 -6.351 1.00 8.20 ? 869 ARG A CA 1 ATOM 6891 C C . ARG A 1 869 ? 25.453 80.099 -5.551 1.00 8.64 ? 869 ARG A C 1 ATOM 6892 O O . ARG A 1 869 ? 24.365 80.300 -6.096 1.00 9.58 ? 869 ARG A O 1 ATOM 6893 C CB . ARG A 1 869 ? 26.980 81.425 -7.086 1.00 9.53 ? 869 ARG A CB 1 ATOM 6894 C CG . ARG A 1 869 ? 27.187 82.566 -6.099 1.00 9.20 ? 869 ARG A CG 1 ATOM 6895 C CD . ARG A 1 869 ? 27.478 83.848 -6.905 1.00 11.81 ? 869 ARG A CD 1 ATOM 6896 N NE . ARG A 1 869 ? 27.608 85.026 -6.015 1.00 15.38 ? 869 ARG A NE 1 ATOM 6897 C CZ . ARG A 1 869 ? 28.745 85.354 -5.417 1.00 13.26 ? 869 ARG A CZ 1 ATOM 6898 N NH1 . ARG A 1 869 ? 29.811 84.643 -5.577 1.00 13.08 ? 869 ARG A NH1 1 ATOM 6899 N NH2 . ARG A 1 869 ? 28.803 86.481 -4.665 1.00 16.73 ? 869 ARG A NH2 1 ATOM 6900 N N . LEU A 1 870 ? 25.585 79.832 -4.261 1.00 10.02 ? 870 LEU A N 1 ATOM 6901 C CA . LEU A 1 870 ? 24.427 79.593 -3.354 1.00 9.88 ? 870 LEU A CA 1 ATOM 6902 C C . LEU A 1 870 ? 24.495 80.461 -2.137 1.00 10.89 ? 870 LEU A C 1 ATOM 6903 O O . LEU A 1 870 ? 25.471 80.416 -1.403 1.00 12.36 ? 870 LEU A O 1 ATOM 6904 C CB . LEU A 1 870 ? 24.436 78.100 -2.976 1.00 11.79 ? 870 LEU A CB 1 ATOM 6905 C CG . LEU A 1 870 ? 24.410 77.296 -4.277 1.00 18.77 ? 870 LEU A CG 1 ATOM 6906 C CD1 . LEU A 1 870 ? 25.024 76.013 -4.045 1.00 20.08 ? 870 LEU A CD1 1 ATOM 6907 C CD2 . LEU A 1 870 ? 23.067 77.266 -4.934 1.00 14.17 ? 870 LEU A CD2 1 ATOM 6908 N N . ALA A 1 871 ? 23.416 81.201 -1.889 1.00 12.29 ? 871 ALA A N 1 ATOM 6909 C CA . ALA A 1 871 ? 23.472 82.107 -0.745 1.00 14.56 ? 871 ALA A CA 1 ATOM 6910 C C . ALA A 1 871 ? 23.150 81.450 0.602 1.00 17.69 ? 871 ALA A C 1 ATOM 6911 O O . ALA A 1 871 ? 23.498 81.984 1.648 1.00 20.99 ? 871 ALA A O 1 ATOM 6912 C CB . ALA A 1 871 ? 22.515 83.285 -0.976 1.00 18.40 ? 871 ALA A CB 1 ATOM 6913 N N . SER A 1 872 ? 22.509 80.307 0.573 1.00 14.24 ? 872 SER A N 1 ATOM 6914 C CA . SER A 1 872 ? 22.107 79.651 1.823 1.00 16.03 ? 872 SER A CA 1 ATOM 6915 C C . SER A 1 872 ? 22.965 78.463 2.200 1.00 13.46 ? 872 SER A C 1 ATOM 6916 O O . SER A 1 872 ? 23.607 77.848 1.351 1.00 13.74 ? 872 SER A O 1 ATOM 6917 C CB . SER A 1 872 ? 20.645 79.179 1.671 1.00 19.50 ? 872 SER A CB 1 ATOM 6918 O OG . SER A 1 872 ? 19.791 80.321 1.659 1.00 26.31 ? 872 SER A OG 1 ATOM 6919 N N . ASP A 1 873 ? 23.003 78.204 3.501 1.00 14.61 ? 873 ASP A N 1 ATOM 6920 C CA . ASP A 1 873 ? 23.657 77.035 4.083 1.00 14.17 ? 873 ASP A CA 1 ATOM 6921 C C . ASP A 1 873 ? 22.646 75.881 3.949 1.00 14.03 ? 873 ASP A C 1 ATOM 6922 O O . ASP A 1 873 ? 21.408 76.101 4.059 1.00 15.53 ? 873 ASP A O 1 ATOM 6923 C CB . ASP A 1 873 ? 23.957 77.259 5.574 1.00 13.24 ? 873 ASP A CB 1 ATOM 6924 C CG . ASP A 1 873 ? 24.446 75.989 6.244 1.00 15.30 ? 873 ASP A CG 1 ATOM 6925 O OD1 . ASP A 1 873 ? 25.545 75.530 5.842 1.00 15.63 ? 873 ASP A OD1 1 ATOM 6926 O OD2 . ASP A 1 873 ? 23.731 75.444 7.120 1.00 16.10 ? 873 ASP A OD2 1 ATOM 6927 N N . ASP A 1 874 ? 23.139 74.657 3.740 1.00 12.75 ? 874 ASP A N 1 ATOM 6928 C CA . ASP A 1 874 ? 22.263 73.480 3.586 1.00 10.68 ? 874 ASP A CA 1 ATOM 6929 C C . ASP A 1 874 ? 22.216 72.557 4.794 1.00 10.59 ? 874 ASP A C 1 ATOM 6930 O O . ASP A 1 874 ? 21.944 71.342 4.683 1.00 13.96 ? 874 ASP A O 1 ATOM 6931 C CB . ASP A 1 874 ? 22.575 72.694 2.311 1.00 10.52 ? 874 ASP A CB 1 ATOM 6932 C CG . ASP A 1 874 ? 24.056 72.379 2.165 1.00 9.43 ? 874 ASP A CG 1 ATOM 6933 O OD1 . ASP A 1 874 ? 24.883 72.773 3.052 1.00 12.07 ? 874 ASP A OD1 1 ATOM 6934 O OD2 . ASP A 1 874 ? 24.352 71.751 1.127 1.00 9.37 ? 874 ASP A OD2 1 ATOM 6935 N N . GLU A 1 875 ? 22.548 73.118 5.951 1.00 12.12 ? 875 GLU A N 1 ATOM 6936 C CA . GLU A 1 875 ? 22.291 72.404 7.199 1.00 13.72 ? 875 GLU A CA 1 ATOM 6937 C C . GLU A 1 875 ? 22.999 71.112 7.452 1.00 13.57 ? 875 GLU A C 1 ATOM 6938 O O . GLU A 1 875 ? 22.452 70.193 8.080 1.00 14.35 ? 875 GLU A O 1 ATOM 6939 C CB . GLU A 1 875 ? 20.762 72.200 7.394 1.00 19.74 ? 875 GLU A CB 1 ATOM 6940 C CG . GLU A 1 875 ? 19.924 73.494 7.439 1.00 24.22 ? 875 GLU A CG 1 ATOM 6941 C CD . GLU A 1 875 ? 18.424 73.148 7.608 1.00 31.38 ? 875 GLU A CD 1 ATOM 6942 O OE1 . GLU A 1 875 ? 18.055 72.497 8.604 1.00 39.92 ? 875 GLU A OE1 1 ATOM 6943 O OE2 . GLU A 1 875 ? 17.621 73.505 6.716 1.00 42.63 ? 875 GLU A OE2 1 ATOM 6944 N N . ARG A 1 876 ? 24.229 71.010 6.947 1.00 10.86 ? 876 ARG A N 1 ATOM 6945 C CA . ARG A 1 876 ? 25.051 69.828 7.228 1.00 12.51 ? 876 ARG A CA 1 ATOM 6946 C C . ARG A 1 876 ? 26.279 70.189 8.055 1.00 12.01 ? 876 ARG A C 1 ATOM 6947 O O . ARG A 1 876 ? 27.151 69.333 8.221 1.00 13.07 ? 876 ARG A O 1 ATOM 6948 C CB . ARG A 1 876 ? 25.440 69.090 5.933 1.00 11.68 ? 876 ARG A CB 1 ATOM 6949 C CG . ARG A 1 876 ? 24.220 68.544 5.178 1.00 11.42 ? 876 ARG A CG 1 ATOM 6950 C CD . ARG A 1 876 ? 23.358 67.602 6.049 1.00 12.07 ? 876 ARG A CD 1 ATOM 6951 N NE . ARG A 1 876 ? 22.314 66.870 5.295 1.00 11.02 ? 876 ARG A NE 1 ATOM 6952 C CZ . ARG A 1 876 ? 21.144 67.420 4.943 1.00 11.38 ? 876 ARG A CZ 1 ATOM 6953 N NH1 . ARG A 1 876 ? 20.904 68.706 5.210 1.00 10.38 ? 876 ARG A NH1 1 ATOM 6954 N NH2 . ARG A 1 876 ? 20.213 66.655 4.403 1.00 9.79 ? 876 ARG A NH2 1 ATOM 6955 N N . GLY A 1 877 ? 26.358 71.422 8.557 1.00 11.63 ? 877 GLY A N 1 ATOM 6956 C CA . GLY A 1 877 ? 27.440 71.812 9.458 1.00 11.78 ? 877 GLY A CA 1 ATOM 6957 C C . GLY A 1 877 ? 28.427 72.805 8.910 1.00 10.72 ? 877 GLY A C 1 ATOM 6958 O O . GLY A 1 877 ? 29.243 73.319 9.700 1.00 12.98 ? 877 GLY A O 1 ATOM 6959 N N . LEU A 1 878 ? 28.382 73.102 7.608 1.00 10.35 ? 878 LEU A N 1 ATOM 6960 C CA . LEU A 1 878 ? 29.365 74.026 7.047 1.00 11.62 ? 878 LEU A CA 1 ATOM 6961 C C . LEU A 1 878 ? 29.112 75.462 7.523 1.00 12.36 ? 878 LEU A C 1 ATOM 6962 O O . LEU A 1 878 ? 30.070 76.227 7.717 1.00 13.67 ? 878 LEU A O 1 ATOM 6963 C CB . LEU A 1 878 ? 29.345 73.910 5.517 1.00 10.42 ? 878 LEU A CB 1 ATOM 6964 C CG . LEU A 1 878 ? 30.147 74.931 4.716 1.00 11.67 ? 878 LEU A CG 1 ATOM 6965 C CD1 . LEU A 1 878 ? 31.651 74.931 5.150 1.00 11.77 ? 878 LEU A CD1 1 ATOM 6966 C CD2 . LEU A 1 878 ? 30.004 74.601 3.207 1.00 14.55 ? 878 LEU A CD2 1 ATOM 6967 N N . GLY A 1 879 ? 27.836 75.802 7.705 1.00 10.96 ? 879 GLY A N 1 ATOM 6968 C CA . GLY A 1 879 ? 27.472 77.126 8.235 1.00 12.62 ? 879 GLY A CA 1 ATOM 6969 C C . GLY A 1 879 ? 27.711 78.291 7.283 1.00 14.88 ? 879 GLY A C 1 ATOM 6970 O O . GLY A 1 879 ? 27.977 79.399 7.731 1.00 15.70 ? 879 GLY A O 1 ATOM 6971 N N . GLN A 1 880 ? 27.751 78.026 5.988 1.00 13.54 ? 880 GLN A N 1 ATOM 6972 C CA . GLN A 1 880 ? 27.858 79.095 5.006 1.00 13.58 ? 880 GLN A CA 1 ATOM 6973 C C . GLN A 1 880 ? 27.329 78.585 3.677 1.00 12.59 ? 880 GLN A C 1 ATOM 6974 O O . GLN A 1 880 ? 27.239 77.393 3.474 1.00 14.58 ? 880 GLN A O 1 ATOM 6975 C CB . GLN A 1 880 ? 29.299 79.628 4.873 1.00 12.53 ? 880 GLN A CB 1 ATOM 6976 C CG . GLN A 1 880 ? 30.337 78.605 4.359 1.00 13.08 ? 880 GLN A CG 1 ATOM 6977 C CD . GLN A 1 880 ? 31.623 79.252 3.849 1.00 13.78 ? 880 GLN A CD 1 ATOM 6978 O OE1 . GLN A 1 880 ? 32.533 79.516 4.604 1.00 18.47 ? 880 GLN A OE1 1 ATOM 6979 N NE2 . GLN A 1 880 ? 31.676 79.496 2.564 1.00 11.18 ? 880 GLN A NE2 1 ATOM 6980 N N . GLY A 1 881 ? 26.983 79.498 2.777 1.00 14.27 ? 881 GLY A N 1 ATOM 6981 C CA . GLY A 1 881 ? 26.637 79.113 1.406 1.00 16.98 ? 881 GLY A CA 1 ATOM 6982 C C . GLY A 1 881 ? 27.958 79.048 0.628 1.00 15.72 ? 881 GLY A C 1 ATOM 6983 O O . GLY A 1 881 ? 29.066 78.858 1.189 1.00 16.05 ? 881 GLY A O 1 ATOM 6984 N N . VAL A 1 882 ? 27.839 79.164 -0.693 1.00 11.38 ? 882 VAL A N 1 ATOM 6985 C CA . VAL A 1 882 ? 29.017 79.124 -1.567 1.00 10.61 ? 882 VAL A CA 1 ATOM 6986 C C . VAL A 1 882 ? 28.934 80.420 -2.342 1.00 10.32 ? 882 VAL A C 1 ATOM 6987 O O . VAL A 1 882 ? 28.200 80.564 -3.342 1.00 9.90 ? 882 VAL A O 1 ATOM 6988 C CB . VAL A 1 882 ? 28.939 77.924 -2.490 1.00 10.73 ? 882 VAL A CB 1 ATOM 6989 C CG1 . VAL A 1 882 ? 30.076 77.982 -3.480 1.00 12.31 ? 882 VAL A CG1 1 ATOM 6990 C CG2 . VAL A 1 882 ? 29.024 76.637 -1.658 1.00 14.49 ? 882 VAL A CG2 1 ATOM 6991 N N . LEU A 1 883 ? 29.705 81.392 -1.860 1.00 10.72 ? 883 LEU A N 1 ATOM 6992 C CA . LEU A 1 883 ? 29.697 82.764 -2.448 1.00 11.38 ? 883 LEU A CA 1 ATOM 6993 C C . LEU A 1 883 ? 31.100 83.230 -2.778 1.00 13.05 ? 883 LEU A C 1 ATOM 6994 O O . LEU A 1 883 ? 31.326 84.450 -2.977 1.00 16.74 ? 883 LEU A O 1 ATOM 6995 C CB . LEU A 1 883 ? 29.026 83.779 -1.464 1.00 12.76 ? 883 LEU A CB 1 ATOM 6996 C CG . LEU A 1 883 ? 27.534 83.467 -1.236 1.00 12.89 ? 883 LEU A CG 1 ATOM 6997 C CD1 . LEU A 1 883 ? 26.908 84.352 -0.080 1.00 15.62 ? 883 LEU A CD1 1 ATOM 6998 C CD2 . LEU A 1 883 ? 26.737 83.689 -2.564 1.00 13.47 ? 883 LEU A CD2 1 ATOM 6999 N N . ASP A 1 884 ? 32.040 82.321 -2.824 1.00 10.29 ? 884 ASP A N 1 ATOM 7000 C CA . ASP A 1 884 ? 33.454 82.572 -3.074 1.00 10.51 ? 884 ASP A CA 1 ATOM 7001 C C . ASP A 1 884 ? 33.953 82.127 -4.441 1.00 10.30 ? 884 ASP A C 1 ATOM 7002 O O . ASP A 1 884 ? 35.141 81.869 -4.641 1.00 11.21 ? 884 ASP A O 1 ATOM 7003 C CB . ASP A 1 884 ? 34.343 81.976 -1.954 1.00 12.44 ? 884 ASP A CB 1 ATOM 7004 C CG . ASP A 1 884 ? 34.118 80.465 -1.733 1.00 14.34 ? 884 ASP A CG 1 ATOM 7005 O OD1 . ASP A 1 884 ? 33.302 79.816 -2.472 1.00 12.58 ? 884 ASP A OD1 1 ATOM 7006 O OD2 . ASP A 1 884 ? 34.774 79.948 -0.779 1.00 16.32 ? 884 ASP A OD2 1 ATOM 7007 N N . ASN A 1 885 ? 33.052 82.108 -5.400 1.00 10.15 ? 885 ASN A N 1 ATOM 7008 C CA . ASN A 1 885 ? 33.390 81.719 -6.749 1.00 9.91 ? 885 ASN A CA 1 ATOM 7009 C C . ASN A 1 885 ? 34.480 82.579 -7.320 1.00 10.72 ? 885 ASN A C 1 ATOM 7010 O O . ASN A 1 885 ? 34.611 83.732 -6.972 1.00 11.79 ? 885 ASN A O 1 ATOM 7011 C CB . ASN A 1 885 ? 32.159 81.830 -7.636 1.00 9.94 ? 885 ASN A CB 1 ATOM 7012 C CG . ASN A 1 885 ? 30.936 81.211 -6.995 1.00 10.87 ? 885 ASN A CG 1 ATOM 7013 O OD1 . ASN A 1 885 ? 30.298 81.785 -6.133 1.00 12.12 ? 885 ASN A OD1 1 ATOM 7014 N ND2 . ASN A 1 885 ? 30.614 80.017 -7.432 1.00 9.57 ? 885 ASN A ND2 1 ATOM 7015 N N . LYS A 1 886 ? 35.252 81.996 -8.217 1.00 10.70 ? 886 LYS A N 1 ATOM 7016 C CA . LYS A 1 886 ? 36.266 82.729 -8.952 1.00 11.99 ? 886 LYS A CA 1 ATOM 7017 C C . LYS A 1 886 ? 36.357 82.151 -10.358 1.00 9.78 ? 886 LYS A C 1 ATOM 7018 O O . LYS A 1 886 ? 35.981 80.982 -10.625 1.00 10.92 ? 886 LYS A O 1 ATOM 7019 C CB . LYS A 1 886 ? 37.618 82.664 -8.227 1.00 16.77 ? 886 LYS A CB 1 ATOM 7020 C CG . LYS A 1 886 ? 38.170 81.265 -8.062 1.00 16.32 ? 886 LYS A CG 1 ATOM 7021 C CD . LYS A 1 886 ? 39.211 81.099 -6.887 1.00 22.38 ? 886 LYS A CD 1 ATOM 7022 C CE . LYS A 1 886 ? 40.566 81.373 -7.421 1.00 17.07 ? 886 LYS A CE 1 ATOM 7023 N NZ . LYS A 1 886 ? 41.683 81.687 -6.495 1.00 20.85 ? 886 LYS A NZ 1 ATOM 7024 N N . PRO A 1 887 ? 36.865 82.922 -11.317 1.00 8.72 ? 887 PRO A N 1 ATOM 7025 C CA . PRO A 1 887 ? 36.953 82.414 -12.689 1.00 9.30 ? 887 PRO A CA 1 ATOM 7026 C C . PRO A 1 887 ? 37.732 81.135 -12.778 1.00 8.86 ? 887 PRO A C 1 ATOM 7027 O O . PRO A 1 887 ? 38.785 80.993 -12.192 1.00 9.88 ? 887 PRO A O 1 ATOM 7028 C CB . PRO A 1 887 ? 37.632 83.547 -13.458 1.00 10.83 ? 887 PRO A CB 1 ATOM 7029 C CG . PRO A 1 887 ? 37.209 84.812 -12.654 1.00 11.57 ? 887 PRO A CG 1 ATOM 7030 C CD . PRO A 1 887 ? 37.164 84.369 -11.231 1.00 10.77 ? 887 PRO A CD 1 ATOM 7031 N N . VAL A 1 888 ? 37.208 80.183 -13.553 1.00 7.49 ? 888 VAL A N 1 ATOM 7032 C CA . VAL A 1 888 ? 37.866 78.894 -13.740 1.00 7.34 ? 888 VAL A CA 1 ATOM 7033 C C . VAL A 1 888 ? 37.816 78.523 -15.196 1.00 7.03 ? 888 VAL A C 1 ATOM 7034 O O . VAL A 1 888 ? 36.783 78.781 -15.875 1.00 8.18 ? 888 VAL A O 1 ATOM 7035 C CB . VAL A 1 888 ? 37.228 77.761 -12.838 1.00 7.67 ? 888 VAL A CB 1 ATOM 7036 C CG1 . VAL A 1 888 ? 35.738 77.650 -13.097 1.00 8.60 ? 888 VAL A CG1 1 ATOM 7037 C CG2 . VAL A 1 888 ? 37.915 76.426 -13.113 1.00 8.29 ? 888 VAL A CG2 1 ATOM 7038 N N . LEU A 1 889 ? 38.879 77.959 -15.728 1.00 6.11 ? 889 LEU A N 1 ATOM 7039 C CA . LEU A 1 889 ? 38.888 77.479 -17.116 1.00 6.55 ? 889 LEU A CA 1 ATOM 7040 C C . LEU A 1 889 ? 38.688 75.943 -17.166 1.00 6.86 ? 889 LEU A C 1 ATOM 7041 O O . LEU A 1 889 ? 39.581 75.157 -16.811 1.00 8.73 ? 889 LEU A O 1 ATOM 7042 C CB . LEU A 1 889 ? 40.221 77.850 -17.798 1.00 8.36 ? 889 LEU A CB 1 ATOM 7043 C CG . LEU A 1 889 ? 40.232 77.403 -19.291 1.00 8.98 ? 889 LEU A CG 1 ATOM 7044 C CD1 . LEU A 1 889 ? 39.391 78.376 -20.143 1.00 9.77 ? 889 LEU A CD1 1 ATOM 7045 C CD2 . LEU A 1 889 ? 41.704 77.328 -19.808 1.00 13.61 ? 889 LEU A CD2 1 ATOM 7046 N N . HIS A 1 890 ? 37.465 75.548 -17.484 1.00 5.72 ? 890 HIS A N 1 ATOM 7047 C CA . HIS A 1 890 ? 37.150 74.119 -17.616 1.00 6.42 ? 890 HIS A CA 1 ATOM 7048 C C . HIS A 1 890 ? 37.539 73.633 -19.009 1.00 6.47 ? 890 HIS A C 1 ATOM 7049 O O . HIS A 1 890 ? 37.293 74.357 -20.009 1.00 7.51 ? 890 HIS A O 1 ATOM 7050 C CB . HIS A 1 890 ? 35.660 73.880 -17.405 1.00 7.01 ? 890 HIS A CB 1 ATOM 7051 C CG . HIS A 1 890 ? 35.222 74.025 -15.996 1.00 6.84 ? 890 HIS A CG 1 ATOM 7052 N ND1 . HIS A 1 890 ? 36.061 73.674 -14.943 1.00 8.80 ? 890 HIS A ND1 1 ATOM 7053 C CD2 . HIS A 1 890 ? 34.050 74.450 -15.468 1.00 7.86 ? 890 HIS A CD2 1 ATOM 7054 C CE1 . HIS A 1 890 ? 35.386 73.884 -13.816 1.00 8.61 ? 890 HIS A CE1 1 ATOM 7055 N NE2 . HIS A 1 890 ? 34.175 74.354 -14.097 1.00 7.79 ? 890 HIS A NE2 1 ATOM 7056 N N . ILE A 1 891 ? 38.054 72.424 -19.115 1.00 5.36 ? 891 ILE A N 1 ATOM 7057 C CA . ILE A 1 891 ? 38.481 71.900 -20.426 1.00 5.82 ? 891 ILE A CA 1 ATOM 7058 C C . ILE A 1 891 ? 37.835 70.548 -20.687 1.00 6.21 ? 891 ILE A C 1 ATOM 7059 O O . ILE A 1 891 ? 37.557 69.765 -19.745 1.00 6.11 ? 891 ILE A O 1 ATOM 7060 C CB . ILE A 1 891 ? 40.026 71.819 -20.537 1.00 5.77 ? 891 ILE A CB 1 ATOM 7061 C CG1 . ILE A 1 891 ? 40.639 70.833 -19.513 1.00 6.85 ? 891 ILE A CG1 1 ATOM 7062 C CG2 . ILE A 1 891 ? 40.588 73.261 -20.344 1.00 7.95 ? 891 ILE A CG2 1 ATOM 7063 C CD1 . ILE A 1 891 ? 42.188 70.635 -19.761 1.00 8.37 ? 891 ILE A CD1 1 ATOM 7064 N N . TYR A 1 892 ? 37.607 70.264 -21.955 1.00 5.44 ? 892 TYR A N 1 ATOM 7065 C CA . TYR A 1 892 ? 36.927 69.036 -22.389 1.00 5.46 ? 892 TYR A CA 1 ATOM 7066 C C . TYR A 1 892 ? 37.351 68.603 -23.768 1.00 5.22 ? 892 TYR A C 1 ATOM 7067 O O . TYR A 1 892 ? 37.951 69.354 -24.543 1.00 5.96 ? 892 TYR A O 1 ATOM 7068 C CB . TYR A 1 892 ? 35.378 69.275 -22.526 1.00 5.76 ? 892 TYR A CB 1 ATOM 7069 C CG . TYR A 1 892 ? 34.744 69.953 -21.370 1.00 4.83 ? 892 TYR A CG 1 ATOM 7070 C CD1 . TYR A 1 892 ? 34.735 71.336 -21.231 1.00 5.66 ? 892 TYR A CD1 1 ATOM 7071 C CD2 . TYR A 1 892 ? 34.126 69.180 -20.354 1.00 6.08 ? 892 TYR A CD2 1 ATOM 7072 C CE1 . TYR A 1 892 ? 34.125 71.926 -20.145 1.00 5.85 ? 892 TYR A CE1 1 ATOM 7073 C CE2 . TYR A 1 892 ? 33.548 69.751 -19.247 1.00 5.79 ? 892 TYR A CE2 1 ATOM 7074 C CZ . TYR A 1 892 ? 33.536 71.124 -19.147 1.00 5.89 ? 892 TYR A CZ 1 ATOM 7075 O OH . TYR A 1 892 ? 32.925 71.669 -18.033 1.00 7.55 ? 892 TYR A OH 1 ATOM 7076 N N . ARG A 1 893 ? 37.042 67.331 -24.082 1.00 6.06 ? 893 ARG A N 1 ATOM 7077 C CA . ARG A 1 893 ? 37.135 66.895 -25.516 1.00 6.27 ? 893 ARG A CA 1 ATOM 7078 C C . ARG A 1 893 ? 35.775 66.269 -25.807 1.00 6.31 ? 893 ARG A C 1 ATOM 7079 O O . ARG A 1 893 ? 35.154 65.630 -24.955 1.00 6.99 ? 893 ARG A O 1 ATOM 7080 C CB . ARG A 1 893 ? 38.213 65.851 -25.726 1.00 6.54 ? 893 ARG A CB 1 ATOM 7081 C CG . ARG A 1 893 ? 39.651 66.318 -25.577 1.00 7.82 ? 893 ARG A CG 1 ATOM 7082 C CD . ARG A 1 893 ? 40.146 67.343 -26.677 1.00 7.89 ? 893 ARG A CD 1 ATOM 7083 N NE . ARG A 1 893 ? 40.177 66.743 -28.010 1.00 8.46 ? 893 ARG A NE 1 ATOM 7084 C CZ . ARG A 1 893 ? 41.113 65.922 -28.471 1.00 7.57 ? 893 ARG A CZ 1 ATOM 7085 N NH1 . ARG A 1 893 ? 42.143 65.525 -27.701 1.00 10.65 ? 893 ARG A NH1 1 ATOM 7086 N NH2 . ARG A 1 893 ? 41.078 65.509 -29.746 1.00 10.74 ? 893 ARG A NH2 1 ATOM 7087 N N . LEU A 1 894 ? 35.290 66.471 -27.045 1.00 6.79 ? 894 LEU A N 1 ATOM 7088 C CA . LEU A 1 894 ? 33.956 65.996 -27.476 1.00 8.41 ? 894 LEU A CA 1 ATOM 7089 C C . LEU A 1 894 ? 34.152 65.043 -28.632 1.00 7.11 ? 894 LEU A C 1 ATOM 7090 O O . LEU A 1 894 ? 34.620 65.451 -29.702 1.00 8.94 ? 894 LEU A O 1 ATOM 7091 C CB . LEU A 1 894 ? 33.123 67.214 -27.876 1.00 8.59 ? 894 LEU A CB 1 ATOM 7092 C CG . LEU A 1 894 ? 31.686 66.830 -28.283 1.00 9.70 ? 894 LEU A CG 1 ATOM 7093 C CD1 . LEU A 1 894 ? 30.933 66.252 -27.083 1.00 13.46 ? 894 LEU A CD1 1 ATOM 7094 C CD2 . LEU A 1 894 ? 30.982 68.082 -28.804 1.00 11.66 ? 894 LEU A CD2 1 ATOM 7095 N N . VAL A 1 895 ? 33.853 63.749 -28.415 1.00 6.87 ? 895 VAL A N 1 ATOM 7096 C CA . VAL A 1 895 ? 34.095 62.715 -29.403 1.00 7.80 ? 895 VAL A CA 1 ATOM 7097 C C . VAL A 1 895 ? 32.802 62.066 -29.866 1.00 8.07 ? 895 VAL A C 1 ATOM 7098 O O . VAL A 1 895 ? 32.117 61.351 -29.104 1.00 8.55 ? 895 VAL A O 1 ATOM 7099 C CB . VAL A 1 895 ? 34.999 61.607 -28.759 1.00 8.65 ? 895 VAL A CB 1 ATOM 7100 C CG1 . VAL A 1 895 ? 35.372 60.620 -29.819 1.00 11.73 ? 895 VAL A CG1 1 ATOM 7101 C CG2 . VAL A 1 895 ? 36.238 62.219 -28.121 1.00 10.94 ? 895 VAL A CG2 1 ATOM 7102 N N . LEU A 1 896 ? 32.412 62.344 -31.117 1.00 9.05 ? 896 LEU A N 1 ATOM 7103 C CA . LEU A 1 896 ? 31.245 61.715 -31.763 1.00 8.93 ? 896 LEU A CA 1 ATOM 7104 C C . LEU A 1 896 ? 31.810 60.574 -32.614 1.00 8.70 ? 896 LEU A C 1 ATOM 7105 O O . LEU A 1 896 ? 32.754 60.773 -33.362 1.00 10.13 ? 896 LEU A O 1 ATOM 7106 C CB . LEU A 1 896 ? 30.537 62.718 -32.679 1.00 9.97 ? 896 LEU A CB 1 ATOM 7107 C CG . LEU A 1 896 ? 29.334 62.072 -33.438 1.00 10.70 ? 896 LEU A CG 1 ATOM 7108 C CD1 . LEU A 1 896 ? 28.192 61.854 -32.546 1.00 11.96 ? 896 LEU A CD1 1 ATOM 7109 C CD2 . LEU A 1 896 ? 28.954 63.026 -34.603 1.00 12.13 ? 896 LEU A CD2 1 ATOM 7110 N N . GLU A 1 897 ? 31.255 59.363 -32.451 1.00 8.84 ? 897 GLU A N 1 ATOM 7111 C CA . GLU A 1 897 ? 31.752 58.201 -33.187 1.00 9.67 ? 897 GLU A CA 1 ATOM 7112 C C . GLU A 1 897 ? 30.662 57.253 -33.580 1.00 9.72 ? 897 GLU A C 1 ATOM 7113 O O . GLU A 1 897 ? 29.617 57.176 -32.949 1.00 10.10 ? 897 GLU A O 1 ATOM 7114 C CB . GLU A 1 897 ? 32.718 57.382 -32.293 1.00 15.04 ? 897 GLU A CB 1 ATOM 7115 C CG . GLU A 1 897 ? 33.847 58.132 -31.615 1.00 17.12 ? 897 GLU A CG 1 ATOM 7116 C CD . GLU A 1 897 ? 34.527 57.260 -30.472 1.00 12.47 ? 897 GLU A CD 1 ATOM 7117 O OE1 . GLU A 1 897 ? 33.895 57.067 -29.379 1.00 17.40 ? 897 GLU A OE1 1 ATOM 7118 O OE2 . GLU A 1 897 ? 35.687 56.911 -30.808 1.00 21.10 ? 897 GLU A OE2 1 ATOM 7119 N N . LYS A 1 898 ? 30.935 56.529 -34.667 1.00 11.52 ? 898 LYS A N 1 ATOM 7120 C CA . LYS A 1 898 ? 30.076 55.413 -35.070 1.00 11.33 ? 898 LYS A CA 1 ATOM 7121 C C . LYS A 1 898 ? 30.518 54.201 -34.269 1.00 14.41 ? 898 LYS A C 1 ATOM 7122 O O . LYS A 1 898 ? 31.710 53.888 -34.196 1.00 17.79 ? 898 LYS A O 1 ATOM 7123 C CB . LYS A 1 898 ? 30.271 55.109 -36.533 1.00 15.46 ? 898 LYS A CB 1 ATOM 7124 C CG . LYS A 1 898 ? 29.829 56.259 -37.423 1.00 19.16 ? 898 LYS A CG 1 ATOM 7125 C CD . LYS A 1 898 ? 28.403 56.855 -37.143 1.00 25.56 ? 898 LYS A CD 1 ATOM 7126 C CE . LYS A 1 898 ? 27.209 55.864 -36.854 1.00 30.71 ? 898 LYS A CE 1 ATOM 7127 N NZ . LYS A 1 898 ? 27.043 54.620 -37.689 1.00 32.29 ? 898 LYS A NZ 1 ATOM 7128 N N . VAL A 1 899 ? 29.571 53.520 -33.656 1.00 11.37 ? 899 VAL A N 1 ATOM 7129 C CA . VAL A 1 899 ? 29.895 52.373 -32.839 1.00 12.11 ? 899 VAL A CA 1 ATOM 7130 C C . VAL A 1 899 ? 29.178 51.067 -33.239 1.00 11.58 ? 899 VAL A C 1 ATOM 7131 O O . VAL A 1 899 ? 29.218 50.077 -32.546 1.00 11.06 ? 899 VAL A O 1 ATOM 7132 C CB . VAL A 1 899 ? 29.583 52.650 -31.324 1.00 12.01 ? 899 VAL A CB 1 ATOM 7133 C CG1 . VAL A 1 899 ? 30.584 53.675 -30.781 1.00 14.86 ? 899 VAL A CG1 1 ATOM 7134 C CG2 . VAL A 1 899 ? 28.178 53.175 -31.145 1.00 12.24 ? 899 VAL A CG2 1 ATOM 7135 N N . ASN A 1 900 ? 28.560 51.078 -34.410 1.00 11.75 ? 900 ASN A N 1 ATOM 7136 C CA . ASN A 1 900 ? 27.808 49.891 -34.850 1.00 13.20 ? 900 ASN A CA 1 ATOM 7137 C C . ASN A 1 900 ? 28.749 48.674 -35.064 1.00 12.59 ? 900 ASN A C 1 ATOM 7138 O O . ASN A 1 900 ? 28.281 47.538 -35.007 1.00 17.20 ? 900 ASN A O 1 ATOM 7139 C CB . ASN A 1 900 ? 27.047 50.198 -36.177 1.00 14.53 ? 900 ASN A CB 1 ATOM 7140 C CG . ASN A 1 900 ? 27.924 50.808 -37.226 1.00 17.96 ? 900 ASN A CG 1 ATOM 7141 O OD1 . ASN A 1 900 ? 28.512 51.878 -37.054 1.00 24.05 ? 900 ASN A OD1 1 ATOM 7142 N ND2 . ASN A 1 900 ? 28.036 50.106 -38.376 1.00 22.29 ? 900 ASN A ND2 1 ATOM 7143 N N . ASN A 1 901 ? 30.027 48.910 -35.289 1.00 10.12 ? 901 ASN A N 1 ATOM 7144 C CA . ASN A 1 901 ? 30.968 47.837 -35.505 1.00 12.01 ? 901 ASN A CA 1 ATOM 7145 C C . ASN A 1 901 ? 31.708 47.421 -34.244 1.00 11.33 ? 901 ASN A C 1 ATOM 7146 O O . ASN A 1 901 ? 32.460 46.477 -34.275 1.00 13.22 ? 901 ASN A O 1 ATOM 7147 C CB . ASN A 1 901 ? 31.970 48.220 -36.588 1.00 15.62 ? 901 ASN A CB 1 ATOM 7148 C CG . ASN A 1 901 ? 31.386 48.144 -37.965 1.00 22.55 ? 901 ASN A CG 1 ATOM 7149 O OD1 . ASN A 1 901 ? 30.707 47.197 -38.290 1.00 26.34 ? 901 ASN A OD1 1 ATOM 7150 N ND2 . ASN A 1 901 ? 31.640 49.154 -38.775 1.00 20.59 ? 901 ASN A ND2 1 ATOM 7151 N N . CYS A 1 902 ? 31.495 48.124 -33.138 1.00 11.29 ? 902 CYS A N 1 ATOM 7152 C CA . CYS A 1 902 ? 32.252 47.819 -31.917 1.00 11.90 ? 902 CYS A CA 1 ATOM 7153 C C . CYS A 1 902 ? 31.708 46.629 -31.175 1.00 12.03 ? 902 CYS A C 1 ATOM 7154 O O . CYS A 1 902 ? 30.493 46.448 -31.069 1.00 13.27 ? 902 CYS A O 1 ATOM 7155 C CB . CYS A 1 902 ? 32.204 48.999 -30.935 1.00 12.39 ? 902 CYS A CB 1 ATOM 7156 S SG . CYS A 1 902 ? 32.914 50.538 -31.554 1.00 14.99 ? 902 CYS A SG 1 ATOM 7157 N N . VAL A 1 903 ? 32.612 45.839 -30.639 1.00 10.79 ? 903 VAL A N 1 ATOM 7158 C CA . VAL A 1 903 ? 32.191 44.696 -29.784 1.00 10.83 ? 903 VAL A CA 1 ATOM 7159 C C . VAL A 1 903 ? 31.921 45.251 -28.346 1.00 12.40 ? 903 VAL A C 1 ATOM 7160 O O . VAL A 1 903 ? 32.839 45.557 -27.566 1.00 12.81 ? 903 VAL A O 1 ATOM 7161 C CB . VAL A 1 903 ? 33.256 43.639 -29.787 1.00 10.04 ? 903 VAL A CB 1 ATOM 7162 C CG1 . VAL A 1 903 ? 32.818 42.487 -28.816 1.00 12.52 ? 903 VAL A CG1 1 ATOM 7163 C CG2 . VAL A 1 903 ? 33.420 43.120 -31.230 1.00 12.46 ? 903 VAL A CG2 1 ATOM 7164 N N . ARG A 1 904 ? 30.667 45.462 -28.030 1.00 11.35 ? 904 ARG A N 1 ATOM 7165 C CA . ARG A 1 904 ? 30.253 46.040 -26.761 1.00 11.09 ? 904 ARG A CA 1 ATOM 7166 C C . ARG A 1 904 ? 29.694 44.982 -25.829 1.00 11.87 ? 904 ARG A C 1 ATOM 7167 O O . ARG A 1 904 ? 29.350 43.850 -26.248 1.00 11.70 ? 904 ARG A O 1 ATOM 7168 C CB . ARG A 1 904 ? 29.161 47.102 -27.012 1.00 11.63 ? 904 ARG A CB 1 ATOM 7169 C CG . ARG A 1 904 ? 29.760 48.365 -27.676 1.00 13.09 ? 904 ARG A CG 1 ATOM 7170 C CD . ARG A 1 904 ? 28.702 49.424 -27.948 1.00 16.67 ? 904 ARG A CD 1 ATOM 7171 N NE . ARG A 1 904 ? 27.951 49.005 -29.114 1.00 15.36 ? 904 ARG A NE 1 ATOM 7172 C CZ . ARG A 1 904 ? 27.007 49.753 -29.678 1.00 16.49 ? 904 ARG A CZ 1 ATOM 7173 N NH1 . ARG A 1 904 ? 26.697 50.933 -29.170 1.00 16.23 ? 904 ARG A NH1 1 ATOM 7174 N NH2 . ARG A 1 904 ? 26.395 49.301 -30.786 1.00 16.68 ? 904 ARG A NH2 1 ATOM 7175 N N . PRO A 1 905 ? 29.636 45.271 -24.524 1.00 9.68 ? 905 PRO A N 1 ATOM 7176 C CA . PRO A 1 905 ? 29.071 44.331 -23.560 1.00 10.08 ? 905 PRO A CA 1 ATOM 7177 C C . PRO A 1 905 ? 27.591 44.109 -23.904 1.00 10.22 ? 905 PRO A C 1 ATOM 7178 O O . PRO A 1 905 ? 26.960 44.957 -24.577 1.00 11.76 ? 905 PRO A O 1 ATOM 7179 C CB . PRO A 1 905 ? 29.200 45.082 -22.219 1.00 10.76 ? 905 PRO A CB 1 ATOM 7180 C CG . PRO A 1 905 ? 30.429 46.010 -22.441 1.00 9.58 ? 905 PRO A CG 1 ATOM 7181 C CD . PRO A 1 905 ? 30.200 46.490 -23.882 1.00 9.20 ? 905 PRO A CD 1 ATOM 7182 N N . SER A 1 906 ? 27.049 42.990 -23.413 1.00 11.53 ? 906 SER A N 1 ATOM 7183 C CA . SER A 1 906 ? 25.632 42.736 -23.599 1.00 14.42 ? 906 SER A CA 1 ATOM 7184 C C . SER A 1 906 ? 24.787 43.729 -22.800 1.00 13.96 ? 906 SER A C 1 ATOM 7185 O O . SER A 1 906 ? 25.286 44.520 -21.971 1.00 14.83 ? 906 SER A O 1 ATOM 7186 C CB . SER A 1 906 ? 25.331 41.323 -23.169 1.00 19.61 ? 906 SER A CB 1 ATOM 7187 O OG . SER A 1 906 ? 25.023 41.324 -21.805 1.00 26.82 ? 906 SER A OG 1 ATOM 7188 N N . LYS A 1 907 ? 23.493 43.721 -23.088 1.00 15.59 ? 907 LYS A N 1 ATOM 7189 C CA . LYS A 1 907 ? 22.571 44.632 -22.422 1.00 17.89 ? 907 LYS A CA 1 ATOM 7190 C C . LYS A 1 907 ? 22.537 44.497 -20.934 1.00 15.86 ? 907 LYS A C 1 ATOM 7191 O O . LYS A 1 907 ? 22.174 45.433 -20.237 1.00 20.10 ? 907 LYS A O 1 ATOM 7192 C CB . LYS A 1 907 ? 21.166 44.411 -22.971 1.00 24.18 ? 907 LYS A CB 1 ATOM 7193 C CG . LYS A 1 907 ? 21.037 44.934 -24.359 1.00 31.10 ? 907 LYS A CG 1 ATOM 7194 C CD . LYS A 1 907 ? 19.590 44.782 -24.809 1.00 37.32 ? 907 LYS A CD 1 ATOM 7195 C CE . LYS A 1 907 ? 19.469 45.065 -26.291 1.00 36.43 ? 907 LYS A CE 1 ATOM 7196 N NZ . LYS A 1 907 ? 18.085 44.759 -26.778 1.00 41.48 ? 907 LYS A NZ 1 ATOM 7197 N N . LEU A 1 908 ? 22.854 43.340 -20.418 1.00 13.72 ? 908 LEU A N 1 ATOM 7198 C CA . LEU A 1 908 ? 22.790 43.175 -18.968 1.00 15.70 ? 908 LEU A CA 1 ATOM 7199 C C . LEU A 1 908 ? 24.109 43.467 -18.246 1.00 14.52 ? 908 LEU A C 1 ATOM 7200 O O . LEU A 1 908 ? 24.190 43.407 -17.017 1.00 16.40 ? 908 LEU A O 1 ATOM 7201 C CB . LEU A 1 908 ? 22.335 41.754 -18.602 1.00 18.87 ? 908 LEU A CB 1 ATOM 7202 C CG . LEU A 1 908 ? 20.946 41.334 -19.130 1.00 22.29 ? 908 LEU A CG 1 ATOM 7203 C CD1 . LEU A 1 908 ? 20.661 39.882 -18.706 1.00 23.88 ? 908 LEU A CD1 1 ATOM 7204 C CD2 . LEU A 1 908 ? 19.855 42.278 -18.575 1.00 24.96 ? 908 LEU A CD2 1 ATOM 7205 N N . HIS A 1 909 ? 25.161 43.777 -18.979 1.00 12.48 ? 909 HIS A N 1 ATOM 7206 C CA . HIS A 1 909 ? 26.461 44.043 -18.345 1.00 11.66 ? 909 HIS A CA 1 ATOM 7207 C C . HIS A 1 909 ? 26.423 45.449 -17.679 1.00 9.87 ? 909 HIS A C 1 ATOM 7208 O O . HIS A 1 909 ? 25.945 46.393 -18.262 1.00 10.64 ? 909 HIS A O 1 ATOM 7209 C CB . HIS A 1 909 ? 27.554 43.984 -19.399 1.00 10.26 ? 909 HIS A CB 1 ATOM 7210 C CG . HIS A 1 909 ? 28.917 43.760 -18.835 1.00 10.15 ? 909 HIS A CG 1 ATOM 7211 N ND1 . HIS A 1 909 ? 29.613 44.735 -18.115 1.00 9.75 ? 909 HIS A ND1 1 ATOM 7212 C CD2 . HIS A 1 909 ? 29.719 42.675 -18.899 1.00 10.57 ? 909 HIS A CD2 1 ATOM 7213 C CE1 . HIS A 1 909 ? 30.785 44.231 -17.765 1.00 10.59 ? 909 HIS A CE1 1 ATOM 7214 N NE2 . HIS A 1 909 ? 30.877 42.973 -18.238 1.00 10.85 ? 909 HIS A NE2 1 ATOM 7215 N N . PRO A 1 910 ? 26.953 45.579 -16.478 1.00 8.82 ? 910 PRO A N 1 ATOM 7216 C CA . PRO A 1 910 ? 26.926 46.889 -15.792 1.00 9.14 ? 910 PRO A CA 1 ATOM 7217 C C . PRO A 1 910 ? 28.003 47.870 -16.167 1.00 7.76 ? 910 PRO A C 1 ATOM 7218 O O . PRO A 1 910 ? 27.967 49.006 -15.630 1.00 8.27 ? 910 PRO A O 1 ATOM 7219 C CB . PRO A 1 910 ? 26.998 46.546 -14.294 1.00 11.81 ? 910 PRO A CB 1 ATOM 7220 C CG . PRO A 1 910 ? 27.416 45.058 -14.234 1.00 12.09 ? 910 PRO A CG 1 ATOM 7221 C CD . PRO A 1 910 ? 27.384 44.463 -15.592 1.00 10.65 ? 910 PRO A CD 1 ATOM 7222 N N . ALA A 1 911 ? 28.971 47.465 -16.984 1.00 7.90 ? 911 ALA A N 1 ATOM 7223 C CA . ALA A 1 911 ? 30.059 48.403 -17.388 1.00 8.41 ? 911 ALA A CA 1 ATOM 7224 C C . ALA A 1 911 ? 29.946 48.873 -18.811 1.00 8.33 ? 911 ALA A C 1 ATOM 7225 O O . ALA A 1 911 ? 29.206 48.300 -19.652 1.00 9.12 ? 911 ALA A O 1 ATOM 7226 C CB . ALA A 1 911 ? 31.411 47.697 -17.246 1.00 9.79 ? 911 ALA A CB 1 ATOM 7227 N N . GLY A 1 912 ? 30.695 49.948 -19.095 1.00 7.78 ? 912 GLY A N 1 ATOM 7228 C CA . GLY A 1 912 ? 30.922 50.410 -20.447 1.00 9.19 ? 912 GLY A CA 1 ATOM 7229 C C . GLY A 1 912 ? 32.408 50.662 -20.646 1.00 6.72 ? 912 GLY A C 1 ATOM 7230 O O . GLY A 1 912 ? 33.139 50.729 -19.659 1.00 7.74 ? 912 GLY A O 1 ATOM 7231 N N . TYR A 1 913 ? 32.858 50.829 -21.881 1.00 7.63 ? 913 TYR A N 1 ATOM 7232 C CA . TYR A 1 913 ? 34.281 50.990 -22.185 1.00 8.06 ? 913 TYR A CA 1 ATOM 7233 C C . TYR A 1 913 ? 34.460 52.034 -23.267 1.00 7.93 ? 913 TYR A C 1 ATOM 7234 O O . TYR A 1 913 ? 33.659 52.134 -24.185 1.00 8.89 ? 913 TYR A O 1 ATOM 7235 C CB . TYR A 1 913 ? 34.897 49.661 -22.624 1.00 8.40 ? 913 TYR A CB 1 ATOM 7236 C CG . TYR A 1 913 ? 34.851 48.646 -21.502 1.00 7.18 ? 913 TYR A CG 1 ATOM 7237 C CD1 . TYR A 1 913 ? 35.738 48.723 -20.451 1.00 8.37 ? 913 TYR A CD1 1 ATOM 7238 C CD2 . TYR A 1 913 ? 33.885 47.648 -21.469 1.00 8.33 ? 913 TYR A CD2 1 ATOM 7239 C CE1 . TYR A 1 913 ? 35.684 47.840 -19.405 1.00 8.43 ? 913 TYR A CE1 1 ATOM 7240 C CE2 . TYR A 1 913 ? 33.828 46.745 -20.419 1.00 8.51 ? 913 TYR A CE2 1 ATOM 7241 C CZ . TYR A 1 913 ? 34.731 46.858 -19.393 1.00 8.79 ? 913 TYR A CZ 1 ATOM 7242 O OH . TYR A 1 913 ? 34.697 45.977 -18.361 1.00 9.76 ? 913 TYR A OH 1 ATOM 7243 N N . LEU A 1 914 ? 35.532 52.803 -23.146 1.00 7.78 ? 914 LEU A N 1 ATOM 7244 C CA . LEU A 1 914 ? 35.845 53.802 -24.157 1.00 7.98 ? 914 LEU A CA 1 ATOM 7245 C C . LEU A 1 914 ? 36.457 53.179 -25.399 1.00 8.93 ? 914 LEU A C 1 ATOM 7246 O O . LEU A 1 914 ? 36.969 52.047 -25.442 1.00 8.46 ? 914 LEU A O 1 ATOM 7247 C CB . LEU A 1 914 ? 36.937 54.768 -23.607 1.00 7.89 ? 914 LEU A CB 1 ATOM 7248 C CG . LEU A 1 914 ? 36.476 55.653 -22.432 1.00 7.86 ? 914 LEU A CG 1 ATOM 7249 C CD1 . LEU A 1 914 ? 37.580 56.675 -22.151 1.00 9.83 ? 914 LEU A CD1 1 ATOM 7250 C CD2 . LEU A 1 914 ? 35.141 56.378 -22.731 1.00 9.06 ? 914 LEU A CD2 1 ATOM 7251 N N . THR A 1 915 ? 36.366 53.934 -26.496 1.00 8.74 ? 915 THR A N 1 ATOM 7252 C CA . THR A 1 915 ? 37.104 53.645 -27.724 1.00 8.26 ? 915 THR A CA 1 ATOM 7253 C C . THR A 1 915 ? 38.519 54.214 -27.591 1.00 8.31 ? 915 THR A C 1 ATOM 7254 O O . THR A 1 915 ? 38.788 55.023 -26.700 1.00 9.45 ? 915 THR A O 1 ATOM 7255 C CB . THR A 1 915 ? 36.456 54.366 -28.913 1.00 10.33 ? 915 THR A CB 1 ATOM 7256 O OG1 . THR A 1 915 ? 36.473 55.762 -28.629 1.00 12.19 ? 915 THR A OG1 1 ATOM 7257 C CG2 . THR A 1 915 ? 35.012 53.897 -29.144 1.00 11.51 ? 915 THR A CG2 1 ATOM 7258 N N . SER A 1 916 ? 39.400 53.815 -28.509 1.00 9.05 ? 916 SER A N 1 ATOM 7259 C CA . SER A 1 916 ? 40.724 54.357 -28.552 1.00 8.91 ? 916 SER A CA 1 ATOM 7260 C C . SER A 1 916 ? 40.742 55.873 -28.647 1.00 9.10 ? 916 SER A C 1 ATOM 7261 O O . SER A 1 916 ? 41.464 56.544 -27.887 1.00 9.15 ? 916 SER A O 1 ATOM 7262 C CB . SER A 1 916 ? 41.443 53.813 -29.792 1.00 11.89 ? 916 SER A CB 1 ATOM 7263 O OG . SER A 1 916 ? 42.660 54.502 -30.061 1.00 19.04 ? 916 SER A OG 1 ATOM 7264 N N . ALA A 1 917 ? 39.929 56.450 -29.525 1.00 8.69 ? 917 ALA A N 1 ATOM 7265 C CA . ALA A 1 917 ? 40.003 57.900 -29.676 1.00 8.58 ? 917 ALA A CA 1 ATOM 7266 C C . ALA A 1 917 ? 39.555 58.593 -28.397 1.00 8.51 ? 917 ALA A C 1 ATOM 7267 O O . ALA A 1 917 ? 40.079 59.680 -28.043 1.00 8.81 ? 917 ALA A O 1 ATOM 7268 C CB . ALA A 1 917 ? 39.115 58.362 -30.848 1.00 10.85 ? 917 ALA A CB 1 ATOM 7269 N N . ALA A 1 918 ? 38.540 58.058 -27.726 1.00 7.94 ? 918 ALA A N 1 ATOM 7270 C CA . ALA A 1 918 ? 38.087 58.725 -26.483 1.00 7.95 ? 918 ALA A CA 1 ATOM 7271 C C . ALA A 1 918 ? 39.117 58.598 -25.366 1.00 6.14 ? 918 ALA A C 1 ATOM 7272 O O . ALA A 1 918 ? 39.289 59.545 -24.574 1.00 7.29 ? 918 ALA A O 1 ATOM 7273 C CB . ALA A 1 918 ? 36.703 58.212 -26.043 1.00 8.74 ? 918 ALA A CB 1 ATOM 7274 N N . HIS A 1 919 ? 39.777 57.451 -25.270 1.00 6.18 ? 919 HIS A N 1 ATOM 7275 C CA . HIS A 1 919 ? 40.773 57.292 -24.234 1.00 6.35 ? 919 HIS A CA 1 ATOM 7276 C C . HIS A 1 919 ? 41.929 58.247 -24.521 1.00 7.02 ? 919 HIS A C 1 ATOM 7277 O O . HIS A 1 919 ? 42.458 58.903 -23.584 1.00 7.21 ? 919 HIS A O 1 ATOM 7278 C CB . HIS A 1 919 ? 41.223 55.824 -24.247 1.00 7.90 ? 919 HIS A CB 1 ATOM 7279 C CG . HIS A 1 919 ? 42.354 55.564 -23.295 1.00 9.55 ? 919 HIS A CG 1 ATOM 7280 N ND1 . HIS A 1 919 ? 43.594 55.171 -23.717 1.00 12.73 ? 919 HIS A ND1 1 ATOM 7281 C CD2 . HIS A 1 919 ? 42.412 55.666 -21.951 1.00 10.40 ? 919 HIS A CD2 1 ATOM 7282 C CE1 . HIS A 1 919 ? 44.394 55.024 -22.674 1.00 10.60 ? 919 HIS A CE1 1 ATOM 7283 N NE2 . HIS A 1 919 ? 43.719 55.324 -21.604 1.00 11.68 ? 919 HIS A NE2 1 ATOM 7284 N N . LYS A 1 920 ? 42.403 58.307 -25.769 1.00 7.83 ? 920 LYS A N 1 ATOM 7285 C CA . LYS A 1 920 ? 43.487 59.254 -26.082 1.00 7.87 ? 920 LYS A CA 1 ATOM 7286 C C . LYS A 1 920 ? 43.046 60.683 -25.798 1.00 7.13 ? 920 LYS A C 1 ATOM 7287 O O . LYS A 1 920 ? 43.858 61.487 -25.304 1.00 7.14 ? 920 LYS A O 1 ATOM 7288 C CB . LYS A 1 920 ? 43.953 59.097 -27.542 1.00 11.52 ? 920 LYS A CB 1 ATOM 7289 C CG . LYS A 1 920 ? 44.859 57.848 -27.654 1.00 13.28 ? 920 LYS A CG 1 ATOM 7290 C CD . LYS A 1 920 ? 45.630 57.803 -28.956 1.00 15.42 ? 920 LYS A CD 1 ATOM 7291 C CE . LYS A 1 920 ? 46.580 56.609 -28.998 1.00 14.09 ? 920 LYS A CE 1 ATOM 7292 N NZ . LYS A 1 920 ? 47.733 56.673 -28.055 1.00 14.69 ? 920 LYS A NZ 1 ATOM 7293 N N . ALA A 1 921 ? 41.787 61.019 -26.084 1.00 6.67 ? 921 ALA A N 1 ATOM 7294 C CA . ALA A 1 921 ? 41.329 62.387 -25.789 1.00 6.75 ? 921 ALA A CA 1 ATOM 7295 C C . ALA A 1 921 ? 41.353 62.659 -24.270 1.00 6.69 ? 921 ALA A C 1 ATOM 7296 O O . ALA A 1 921 ? 41.717 63.745 -23.825 1.00 6.89 ? 921 ALA A O 1 ATOM 7297 C CB . ALA A 1 921 ? 39.904 62.544 -26.379 1.00 7.56 ? 921 ALA A CB 1 ATOM 7298 N N . SER A 1 922 ? 40.983 61.669 -23.454 1.00 6.53 ? 922 SER A N 1 ATOM 7299 C CA . SER A 1 922 ? 41.048 61.843 -21.993 1.00 6.15 ? 922 SER A CA 1 ATOM 7300 C C . SER A 1 922 ? 42.505 62.061 -21.568 1.00 7.30 ? 922 SER A C 1 ATOM 7301 O O . SER A 1 922 ? 42.809 62.969 -20.787 1.00 7.90 ? 922 SER A O 1 ATOM 7302 C CB . SER A 1 922 ? 40.473 60.619 -21.301 1.00 6.86 ? 922 SER A CB 1 ATOM 7303 O OG . SER A 1 922 ? 40.628 60.753 -19.876 1.00 7.58 ? 922 SER A OG 1 ATOM 7304 N N . GLN A 1 923 ? 43.429 61.275 -22.120 1.00 6.47 ? 923 GLN A N 1 ATOM 7305 C CA . GLN A 1 923 ? 44.850 61.457 -21.788 1.00 6.34 ? 923 GLN A CA 1 ATOM 7306 C C . GLN A 1 923 ? 45.336 62.841 -22.203 1.00 6.28 ? 923 GLN A C 1 ATOM 7307 O O . GLN A 1 923 ? 46.229 63.405 -21.524 1.00 7.26 ? 923 GLN A O 1 ATOM 7308 C CB . GLN A 1 923 ? 45.694 60.357 -22.458 1.00 6.87 ? 923 GLN A CB 1 ATOM 7309 C CG . GLN A 1 923 ? 45.407 58.976 -21.885 1.00 6.71 ? 923 GLN A CG 1 ATOM 7310 C CD . GLN A 1 923 ? 46.333 57.935 -22.481 1.00 8.14 ? 923 GLN A CD 1 ATOM 7311 O OE1 . GLN A 1 923 ? 46.477 57.862 -23.723 1.00 9.67 ? 923 GLN A OE1 1 ATOM 7312 N NE2 . GLN A 1 923 ? 46.960 57.096 -21.622 1.00 8.86 ? 923 GLN A NE2 1 ATOM 7313 N N . SER A 1 924 ? 44.827 63.410 -23.303 1.00 6.42 ? 924 SER A N 1 ATOM 7314 C CA . SER A 1 924 ? 45.267 64.728 -23.764 1.00 6.52 ? 924 SER A CA 1 ATOM 7315 C C . SER A 1 924 ? 44.882 65.829 -22.777 1.00 6.72 ? 924 SER A C 1 ATOM 7316 O O . SER A 1 924 ? 45.497 66.900 -22.745 1.00 9.59 ? 924 SER A O 1 ATOM 7317 C CB . SER A 1 924 ? 44.652 65.051 -25.152 1.00 8.50 ? 924 SER A CB 1 ATOM 7318 O OG . SER A 1 924 ? 43.260 65.481 -25.054 1.00 9.56 ? 924 SER A OG 1 ATOM 7319 N N . LEU A 1 925 ? 43.824 65.568 -22.006 1.00 6.71 ? 925 LEU A N 1 ATOM 7320 C CA . LEU A 1 925 ? 43.345 66.526 -21.002 1.00 7.50 ? 925 LEU A CA 1 ATOM 7321 C C . LEU A 1 925 ? 44.067 66.342 -19.666 1.00 7.38 ? 925 LEU A C 1 ATOM 7322 O O . LEU A 1 925 ? 44.460 67.318 -19.006 1.00 9.71 ? 925 LEU A O 1 ATOM 7323 C CB . LEU A 1 925 ? 41.828 66.351 -20.705 1.00 7.25 ? 925 LEU A CB 1 ATOM 7324 C CG . LEU A 1 925 ? 40.943 66.621 -21.935 1.00 6.74 ? 925 LEU A CG 1 ATOM 7325 C CD1 . LEU A 1 925 ? 39.522 66.241 -21.557 1.00 9.13 ? 925 LEU A CD1 1 ATOM 7326 C CD2 . LEU A 1 925 ? 40.978 68.114 -22.372 1.00 9.13 ? 925 LEU A CD2 1 ATOM 7327 N N . LEU A 1 926 ? 44.232 65.092 -19.240 1.00 6.81 ? 926 LEU A N 1 ATOM 7328 C CA . LEU A 1 926 ? 44.800 64.845 -17.912 1.00 6.74 ? 926 LEU A CA 1 ATOM 7329 C C . LEU A 1 926 ? 46.295 64.804 -17.883 1.00 6.56 ? 926 LEU A C 1 ATOM 7330 O O . LEU A 1 926 ? 46.863 65.213 -16.860 1.00 8.45 ? 926 LEU A O 1 ATOM 7331 C CB . LEU A 1 926 ? 44.210 63.541 -17.356 1.00 9.22 ? 926 LEU A CB 1 ATOM 7332 C CG . LEU A 1 926 ? 42.677 63.609 -17.103 1.00 9.93 ? 926 LEU A CG 1 ATOM 7333 C CD1 . LEU A 1 926 ? 42.195 62.214 -16.581 1.00 12.97 ? 926 LEU A CD1 1 ATOM 7334 C CD2 . LEU A 1 926 ? 42.382 64.745 -16.119 1.00 14.43 ? 926 LEU A CD2 1 ATOM 7335 N N . ASP A 1 927 ? 46.935 64.332 -18.940 1.00 6.34 ? 927 ASP A N 1 ATOM 7336 C CA . ASP A 1 927 ? 48.406 64.225 -18.948 1.00 7.08 ? 927 ASP A CA 1 ATOM 7337 C C . ASP A 1 927 ? 48.966 64.758 -20.256 1.00 6.65 ? 927 ASP A C 1 ATOM 7338 O O . ASP A 1 927 ? 49.520 64.026 -21.070 1.00 7.18 ? 927 ASP A O 1 ATOM 7339 C CB . ASP A 1 927 ? 48.847 62.793 -18.700 1.00 7.86 ? 927 ASP A CB 1 ATOM 7340 C CG . ASP A 1 927 ? 48.547 62.355 -17.250 1.00 8.59 ? 927 ASP A CG 1 ATOM 7341 O OD1 . ASP A 1 927 ? 49.251 62.758 -16.271 1.00 8.20 ? 927 ASP A OD1 1 ATOM 7342 O OD2 . ASP A 1 927 ? 47.530 61.662 -17.121 1.00 9.36 ? 927 ASP A OD2 1 ATOM 7343 N N . PRO A 1 928 ? 48.783 66.057 -20.502 1.00 7.31 ? 928 PRO A N 1 ATOM 7344 C CA . PRO A 1 928 ? 49.299 66.685 -21.738 1.00 6.70 ? 928 PRO A CA 1 ATOM 7345 C C . PRO A 1 928 ? 50.809 66.687 -21.738 1.00 6.96 ? 928 PRO A C 1 ATOM 7346 O O . PRO A 1 928 ? 51.454 66.409 -20.714 1.00 7.47 ? 928 PRO A O 1 ATOM 7347 C CB . PRO A 1 928 ? 48.768 68.114 -21.623 1.00 8.96 ? 928 PRO A CB 1 ATOM 7348 C CG . PRO A 1 928 ? 48.735 68.387 -20.152 1.00 10.77 ? 928 PRO A CG 1 ATOM 7349 C CD . PRO A 1 928 ? 48.181 67.049 -19.580 1.00 8.65 ? 928 PRO A CD 1 ATOM 7350 N N . LEU A 1 929 ? 51.430 67.040 -22.871 1.00 7.29 ? 929 LEU A N 1 ATOM 7351 C CA . LEU A 1 929 ? 52.840 67.313 -22.833 1.00 5.98 ? 929 LEU A CA 1 ATOM 7352 C C . LEU A 1 929 ? 53.147 68.468 -21.895 1.00 7.55 ? 929 LEU A C 1 ATOM 7353 O O . LEU A 1 929 ? 52.368 69.403 -21.798 1.00 9.68 ? 929 LEU A O 1 ATOM 7354 C CB . LEU A 1 929 ? 53.371 67.701 -24.243 1.00 7.79 ? 929 LEU A CB 1 ATOM 7355 C CG . LEU A 1 929 ? 53.162 66.684 -25.369 1.00 6.95 ? 929 LEU A CG 1 ATOM 7356 C CD1 . LEU A 1 929 ? 53.768 67.288 -26.649 1.00 7.89 ? 929 LEU A CD1 1 ATOM 7357 C CD2 . LEU A 1 929 ? 53.875 65.364 -25.041 1.00 6.86 ? 929 LEU A CD2 1 ATOM 7358 N N . ASP A 1 930 ? 54.279 68.391 -21.220 1.00 6.74 ? 930 ASP A N 1 ATOM 7359 C CA . ASP A 1 930 ? 54.772 69.529 -20.389 1.00 6.92 ? 930 ASP A CA 1 ATOM 7360 C C . ASP A 1 930 ? 55.685 70.372 -21.260 1.00 8.04 ? 930 ASP A C 1 ATOM 7361 O O . ASP A 1 930 ? 56.428 69.812 -22.099 1.00 8.60 ? 930 ASP A O 1 ATOM 7362 C CB . ASP A 1 930 ? 55.533 69.013 -19.172 1.00 7.03 ? 930 ASP A CB 1 ATOM 7363 C CG . ASP A 1 930 ? 54.752 67.967 -18.457 1.00 8.85 ? 930 ASP A CG 1 ATOM 7364 O OD1 . ASP A 1 930 ? 53.667 68.374 -17.957 1.00 11.13 ? 930 ASP A OD1 1 ATOM 7365 O OD2 . ASP A 1 930 ? 55.101 66.767 -18.423 1.00 9.28 ? 930 ASP A OD2 1 ATOM 7366 N N . LYS A 1 931 ? 55.674 71.679 -21.055 1.00 7.81 ? 931 LYS A N 1 ATOM 7367 C CA . LYS A 1 931 ? 56.454 72.601 -21.879 1.00 7.32 ? 931 LYS A CA 1 ATOM 7368 C C . LYS A 1 931 ? 57.412 73.399 -21.024 1.00 8.08 ? 931 LYS A C 1 ATOM 7369 O O . LYS A 1 931 ? 57.009 74.011 -20.014 1.00 8.78 ? 931 LYS A O 1 ATOM 7370 C CB . LYS A 1 931 ? 55.510 73.558 -22.619 1.00 9.83 ? 931 LYS A CB 1 ATOM 7371 C CG . LYS A 1 931 ? 54.524 72.843 -23.567 1.00 9.36 ? 931 LYS A CG 1 ATOM 7372 C CD . LYS A 1 931 ? 53.587 73.881 -24.257 1.00 15.74 ? 931 LYS A CD 1 ATOM 7373 C CE . LYS A 1 931 ? 52.756 74.682 -23.263 1.00 20.39 ? 931 LYS A CE 1 ATOM 7374 N NZ . LYS A 1 931 ? 51.983 75.680 -23.934 1.00 18.88 ? 931 LYS A NZ 1 ATOM 7375 N N . PHE A 1 932 ? 58.670 73.459 -21.436 1.00 7.28 ? 932 PHE A N 1 ATOM 7376 C CA . PHE A 1 932 ? 59.702 74.175 -20.683 1.00 6.95 ? 932 PHE A CA 1 ATOM 7377 C C . PHE A 1 932 ? 60.371 75.201 -21.577 1.00 7.75 ? 932 PHE A C 1 ATOM 7378 O O . PHE A 1 932 ? 60.723 74.878 -22.741 1.00 8.64 ? 932 PHE A O 1 ATOM 7379 C CB . PHE A 1 932 ? 60.784 73.191 -20.235 1.00 6.86 ? 932 PHE A CB 1 ATOM 7380 C CG . PHE A 1 932 ? 60.287 72.092 -19.324 1.00 7.77 ? 932 PHE A CG 1 ATOM 7381 C CD1 . PHE A 1 932 ? 59.700 70.936 -19.824 1.00 8.58 ? 932 PHE A CD1 1 ATOM 7382 C CD2 . PHE A 1 932 ? 60.438 72.230 -17.953 1.00 8.88 ? 932 PHE A CD2 1 ATOM 7383 C CE1 . PHE A 1 932 ? 59.247 69.869 -18.965 1.00 9.14 ? 932 PHE A CE1 1 ATOM 7384 C CE2 . PHE A 1 932 ? 60.007 71.197 -17.056 1.00 10.69 ? 932 PHE A CE2 1 ATOM 7385 C CZ . PHE A 1 932 ? 59.411 70.028 -17.582 1.00 10.80 ? 932 PHE A CZ 1 ATOM 7386 N N . ILE A 1 933 ? 60.587 76.395 -21.052 1.00 7.83 ? 933 ILE A N 1 ATOM 7387 C CA . ILE A 1 933 ? 61.271 77.443 -21.825 1.00 7.58 ? 933 ILE A CA 1 ATOM 7388 C C . ILE A 1 933 ? 62.634 77.677 -21.188 1.00 7.53 ? 933 ILE A C 1 ATOM 7389 O O . ILE A 1 933 ? 62.692 77.955 -19.975 1.00 8.51 ? 933 ILE A O 1 ATOM 7390 C CB . ILE A 1 933 ? 60.459 78.759 -21.767 1.00 7.86 ? 933 ILE A CB 1 ATOM 7391 C CG1 . ILE A 1 933 ? 59.072 78.553 -22.361 1.00 8.13 ? 933 ILE A CG1 1 ATOM 7392 C CG2 . ILE A 1 933 ? 61.231 79.879 -22.504 1.00 8.48 ? 933 ILE A CG2 1 ATOM 7393 C CD1 . ILE A 1 933 ? 58.123 79.745 -22.067 1.00 9.20 ? 933 ILE A CD1 1 ATOM 7394 N N . PHE A 1 934 ? 63.745 77.570 -21.932 1.00 7.43 ? 934 PHE A N 1 ATOM 7395 C CA . PHE A 1 934 ? 65.061 77.787 -21.318 1.00 8.97 ? 934 PHE A CA 1 ATOM 7396 C C . PHE A 1 934 ? 65.144 79.268 -20.852 1.00 9.64 ? 934 PHE A C 1 ATOM 7397 O O . PHE A 1 934 ? 64.812 80.183 -21.598 1.00 10.07 ? 934 PHE A O 1 ATOM 7398 C CB . PHE A 1 934 ? 66.175 77.432 -22.313 1.00 9.72 ? 934 PHE A CB 1 ATOM 7399 C CG . PHE A 1 934 ? 67.545 77.509 -21.682 1.00 9.26 ? 934 PHE A CG 1 ATOM 7400 C CD1 . PHE A 1 934 ? 67.941 76.553 -20.775 1.00 9.80 ? 934 PHE A CD1 1 ATOM 7401 C CD2 . PHE A 1 934 ? 68.378 78.580 -21.940 1.00 10.73 ? 934 PHE A CD2 1 ATOM 7402 C CE1 . PHE A 1 934 ? 69.185 76.668 -20.100 1.00 13.61 ? 934 PHE A CE1 1 ATOM 7403 C CE2 . PHE A 1 934 ? 69.604 78.716 -21.301 1.00 13.52 ? 934 PHE A CE2 1 ATOM 7404 C CZ . PHE A 1 934 ? 70.020 77.782 -20.380 1.00 15.20 ? 934 PHE A CZ 1 ATOM 7405 N N . ALA A 1 935 ? 65.580 79.477 -19.606 1.00 9.91 ? 935 ALA A N 1 ATOM 7406 C CA . ALA A 1 935 ? 65.476 80.776 -18.994 1.00 11.38 ? 935 ALA A CA 1 ATOM 7407 C C . ALA A 1 935 ? 66.577 81.749 -19.227 1.00 16.78 ? 935 ALA A C 1 ATOM 7408 O O . ALA A 1 935 ? 66.340 82.943 -18.954 1.00 20.38 ? 935 ALA A O 1 ATOM 7409 C CB . ALA A 1 935 ? 65.303 80.577 -17.501 1.00 15.00 ? 935 ALA A CB 1 ATOM 7410 N N . GLU A 1 936 ? 67.728 81.315 -19.710 1.00 14.17 ? 936 GLU A N 1 ATOM 7411 C CA . GLU A 1 936 ? 68.849 82.225 -19.956 1.00 16.81 ? 936 GLU A CA 1 ATOM 7412 C C . GLU A 1 936 ? 69.097 82.325 -21.452 1.00 20.88 ? 936 GLU A C 1 ATOM 7413 O O . GLU A 1 936 ? 68.363 81.763 -22.239 1.00 30.93 ? 936 GLU A O 1 ATOM 7414 C CB A GLU A 1 936 ? 69.997 81.852 -19.023 0.50 22.03 ? 936 GLU A CB 1 ATOM 7415 C CB B GLU A 1 936 ? 70.216 81.639 -19.431 0.50 19.75 ? 936 GLU A CB 1 ATOM 7416 C CG A GLU A 1 936 ? 69.685 82.017 -17.543 0.50 27.82 ? 936 GLU A CG 1 ATOM 7417 C CG B GLU A 1 936 ? 70.389 81.284 -17.939 0.50 30.39 ? 936 GLU A CG 1 ATOM 7418 C CD A GLU A 1 936 ? 69.423 83.462 -17.149 0.50 36.43 ? 936 GLU A CD 1 ATOM 7419 C CD B GLU A 1 936 ? 71.590 80.309 -17.680 0.50 36.89 ? 936 GLU A CD 1 ATOM 7420 O OE1 A GLU A 1 936 ? 68.669 83.688 -16.176 0.50 40.40 ? 936 GLU A OE1 1 ATOM 7421 O OE1 B GLU A 1 936 ? 71.389 79.078 -17.609 0.50 36.81 ? 936 GLU A OE1 1 ATOM 7422 O OE2 A GLU A 1 936 ? 69.951 84.367 -17.820 0.50 41.24 ? 936 GLU A OE2 1 ATOM 7423 O OE2 B GLU A 1 936 ? 72.749 80.774 -17.577 0.50 42.05 ? 936 GLU A OE2 1 ATOM 7424 N N . ASN A 1 937 ? 70.113 83.080 -21.867 1.00 13.72 ? 937 ASN A N 1 ATOM 7425 C CA . ASN A 1 937 ? 70.302 83.266 -23.292 1.00 12.89 ? 937 ASN A CA 1 ATOM 7426 C C . ASN A 1 937 ? 70.829 82.120 -24.079 1.00 10.64 ? 937 ASN A C 1 ATOM 7427 O O . ASN A 1 937 ? 70.412 81.918 -25.233 1.00 12.67 ? 937 ASN A O 1 ATOM 7428 C CB . ASN A 1 937 ? 71.206 84.479 -23.515 1.00 14.30 ? 937 ASN A CB 1 ATOM 7429 C CG . ASN A 1 937 ? 70.505 85.803 -23.189 1.00 17.98 ? 937 ASN A CG 1 ATOM 7430 O OD1 . ASN A 1 937 ? 69.277 85.888 -23.113 1.00 17.84 ? 937 ASN A OD1 1 ATOM 7431 N ND2 . ASN A 1 937 ? 71.302 86.843 -23.012 1.00 23.11 ? 937 ASN A ND2 1 ATOM 7432 N N . GLU A 1 938 ? 71.719 81.349 -23.458 1.00 11.76 ? 938 GLU A N 1 ATOM 7433 C CA . GLU A 1 938 ? 72.376 80.268 -24.142 1.00 13.18 ? 938 GLU A CA 1 ATOM 7434 C C . GLU A 1 938 ? 72.477 79.026 -23.271 1.00 12.18 ? 938 GLU A C 1 ATOM 7435 O O . GLU A 1 938 ? 72.920 79.086 -22.155 1.00 14.77 ? 938 GLU A O 1 ATOM 7436 C CB . GLU A 1 938 ? 73.815 80.672 -24.563 1.00 18.18 ? 938 GLU A CB 1 ATOM 7437 C CG . GLU A 1 938 ? 74.405 79.508 -25.385 1.00 22.86 ? 938 GLU A CG 1 ATOM 7438 C CD . GLU A 1 938 ? 75.654 79.838 -26.193 1.00 33.71 ? 938 GLU A CD 1 ATOM 7439 O OE1 . GLU A 1 938 ? 76.340 80.834 -25.870 1.00 34.13 ? 938 GLU A OE1 1 ATOM 7440 O OE2 . GLU A 1 938 ? 75.947 79.066 -27.151 1.00 37.30 ? 938 GLU A OE2 1 ATOM 7441 N N . TRP A 1 939 ? 72.033 77.910 -23.849 1.00 12.23 ? 939 TRP A N 1 ATOM 7442 C CA . TRP A 1 939 ? 72.116 76.599 -23.130 1.00 11.47 ? 939 TRP A CA 1 ATOM 7443 C C . TRP A 1 939 ? 73.304 75.842 -23.648 1.00 13.73 ? 939 TRP A C 1 ATOM 7444 O O . TRP A 1 939 ? 73.268 75.266 -24.709 1.00 14.83 ? 939 TRP A O 1 ATOM 7445 C CB . TRP A 1 939 ? 70.777 75.878 -23.373 1.00 10.84 ? 939 TRP A CB 1 ATOM 7446 C CG . TRP A 1 939 ? 70.658 74.503 -22.755 1.00 9.02 ? 939 TRP A CG 1 ATOM 7447 C CD1 . TRP A 1 939 ? 71.535 73.844 -21.926 1.00 10.14 ? 939 TRP A CD1 1 ATOM 7448 C CD2 . TRP A 1 939 ? 69.577 73.617 -23.012 1.00 9.35 ? 939 TRP A CD2 1 ATOM 7449 N NE1 . TRP A 1 939 ? 71.043 72.577 -21.661 1.00 9.57 ? 939 TRP A NE1 1 ATOM 7450 C CE2 . TRP A 1 939 ? 69.844 72.417 -22.313 1.00 7.97 ? 939 TRP A CE2 1 ATOM 7451 C CE3 . TRP A 1 939 ? 68.417 73.712 -23.773 1.00 9.88 ? 939 TRP A CE3 1 ATOM 7452 C CZ2 . TRP A 1 939 ? 68.989 71.321 -22.359 1.00 9.56 ? 939 TRP A CZ2 1 ATOM 7453 C CZ3 . TRP A 1 939 ? 67.560 72.638 -23.822 1.00 9.38 ? 939 TRP A CZ3 1 ATOM 7454 C CH2 . TRP A 1 939 ? 67.852 71.431 -23.115 1.00 9.17 ? 939 TRP A CH2 1 ATOM 7455 N N . ILE A 1 940 ? 74.389 75.875 -22.868 1.00 14.61 ? 940 ILE A N 1 ATOM 7456 C CA . ILE A 1 940 ? 75.597 75.165 -23.324 1.00 17.02 ? 940 ILE A CA 1 ATOM 7457 C C . ILE A 1 940 ? 75.477 73.622 -23.147 1.00 12.63 ? 940 ILE A C 1 ATOM 7458 O O . ILE A 1 940 ? 75.052 73.173 -22.073 1.00 14.74 ? 940 ILE A O 1 ATOM 7459 C CB . ILE A 1 940 ? 76.809 75.754 -22.582 1.00 20.58 ? 940 ILE A CB 1 ATOM 7460 C CG1 . ILE A 1 940 ? 76.868 77.268 -22.903 1.00 24.31 ? 940 ILE A CG1 1 ATOM 7461 C CG2 . ILE A 1 940 ? 78.092 75.115 -23.067 1.00 23.56 ? 940 ILE A CG2 1 ATOM 7462 C CD1 . ILE A 1 940 ? 77.886 78.035 -22.093 1.00 29.53 ? 940 ILE A CD1 1 ATOM 7463 N N . GLY A 1 941 ? 75.795 72.870 -24.176 1.00 14.46 ? 941 GLY A N 1 ATOM 7464 C CA . GLY A 1 941 ? 75.711 71.417 -24.040 1.00 12.74 ? 941 GLY A CA 1 ATOM 7465 C C . GLY A 1 941 ? 74.333 70.810 -24.274 1.00 13.45 ? 941 GLY A C 1 ATOM 7466 O O . GLY A 1 941 ? 74.131 69.601 -24.039 1.00 12.54 ? 941 GLY A O 1 ATOM 7467 N N . ALA A 1 942 ? 73.388 71.584 -24.832 1.00 12.89 ? 942 ALA A N 1 ATOM 7468 C CA . ALA A 1 942 ? 72.037 71.112 -25.063 1.00 11.93 ? 942 ALA A CA 1 ATOM 7469 C C . ALA A 1 942 ? 71.953 69.938 -26.000 1.00 12.27 ? 942 ALA A C 1 ATOM 7470 O O . ALA A 1 942 ? 72.673 69.850 -26.997 1.00 14.72 ? 942 ALA A O 1 ATOM 7471 C CB . ALA A 1 942 ? 71.166 72.278 -25.621 1.00 13.56 ? 942 ALA A CB 1 ATOM 7472 N N . GLN A 1 943 ? 71.097 68.972 -25.682 1.00 12.04 ? 943 GLN A N 1 ATOM 7473 C CA . GLN A 1 943 ? 70.858 67.825 -26.490 1.00 12.84 ? 943 GLN A CA 1 ATOM 7474 C C . GLN A 1 943 ? 69.427 67.798 -27.047 1.00 10.66 ? 943 GLN A C 1 ATOM 7475 O O . GLN A 1 943 ? 68.496 68.405 -26.429 1.00 12.68 ? 943 GLN A O 1 ATOM 7476 C CB . GLN A 1 943 ? 71.089 66.527 -25.695 1.00 13.19 ? 943 GLN A CB 1 ATOM 7477 C CG . GLN A 1 943 ? 72.489 66.489 -25.131 1.00 17.85 ? 943 GLN A CG 1 ATOM 7478 C CD . GLN A 1 943 ? 72.744 65.207 -24.319 1.00 23.06 ? 943 GLN A CD 1 ATOM 7479 O OE1 . GLN A 1 943 ? 71.828 64.718 -23.637 1.00 28.33 ? 943 GLN A OE1 1 ATOM 7480 N NE2 . GLN A 1 943 ? 73.988 64.682 -24.369 1.00 26.60 ? 943 GLN A NE2 1 ATOM 7481 N N . GLY A 1 944 ? 69.179 67.063 -28.097 1.00 10.72 ? 944 GLY A N 1 ATOM 7482 C CA . GLY A 1 944 ? 67.934 67.130 -28.784 1.00 9.96 ? 944 GLY A CA 1 ATOM 7483 C C . GLY A 1 944 ? 66.795 66.266 -28.279 1.00 9.45 ? 944 GLY A C 1 ATOM 7484 O O . GLY A 1 944 ? 65.621 66.551 -28.561 1.00 11.67 ? 944 GLY A O 1 ATOM 7485 N N . GLN A 1 945 ? 67.114 65.170 -27.616 1.00 10.92 ? 945 GLN A N 1 ATOM 7486 C CA . GLN A 1 945 ? 66.064 64.233 -27.216 1.00 10.36 ? 945 GLN A CA 1 ATOM 7487 C C . GLN A 1 945 ? 66.554 63.344 -26.101 1.00 10.56 ? 945 GLN A C 1 ATOM 7488 O O . GLN A 1 945 ? 67.770 63.151 -25.924 1.00 12.07 ? 945 GLN A O 1 ATOM 7489 C CB . GLN A 1 945 ? 65.806 63.358 -28.417 1.00 11.18 ? 945 GLN A CB 1 ATOM 7490 C CG . GLN A 1 945 ? 64.615 62.456 -28.383 1.00 15.76 ? 945 GLN A CG 1 ATOM 7491 C CD . GLN A 1 945 ? 64.547 61.547 -29.617 1.00 19.68 ? 945 GLN A CD 1 ATOM 7492 O OE1 . GLN A 1 945 ? 63.759 61.764 -30.519 1.00 21.56 ? 945 GLN A OE1 1 ATOM 7493 N NE2 . GLN A 1 945 ? 65.383 60.550 -29.639 1.00 20.10 ? 945 GLN A NE2 1 ATOM 7494 N N . PHE A 1 946 ? 65.591 62.891 -25.303 1.00 8.66 ? 946 PHE A N 1 ATOM 7495 C CA . PHE A 1 946 ? 65.837 61.859 -24.258 1.00 8.16 ? 946 PHE A CA 1 ATOM 7496 C C . PHE A 1 946 ? 64.722 60.839 -24.381 1.00 7.77 ? 946 PHE A C 1 ATOM 7497 O O . PHE A 1 946 ? 63.580 61.166 -24.579 1.00 8.25 ? 946 PHE A O 1 ATOM 7498 C CB . PHE A 1 946 ? 65.857 62.474 -22.847 1.00 9.17 ? 946 PHE A CB 1 ATOM 7499 C CG . PHE A 1 946 ? 65.724 61.457 -21.737 1.00 9.23 ? 946 PHE A CG 1 ATOM 7500 C CD1 . PHE A 1 946 ? 66.765 60.616 -21.433 1.00 11.34 ? 946 PHE A CD1 1 ATOM 7501 C CD2 . PHE A 1 946 ? 64.488 61.337 -21.071 1.00 8.67 ? 946 PHE A CD2 1 ATOM 7502 C CE1 . PHE A 1 946 ? 66.585 59.587 -20.441 1.00 10.84 ? 946 PHE A CE1 1 ATOM 7503 C CE2 . PHE A 1 946 ? 64.314 60.316 -20.090 1.00 10.24 ? 946 PHE A CE2 1 ATOM 7504 C CZ . PHE A 1 946 ? 65.349 59.456 -19.794 1.00 11.06 ? 946 PHE A CZ 1 ATOM 7505 N N . GLY A 1 947 ? 65.069 59.542 -24.273 1.00 9.08 ? 947 GLY A N 1 ATOM 7506 C CA . GLY A 1 947 ? 64.069 58.490 -24.307 1.00 9.77 ? 947 GLY A CA 1 ATOM 7507 C C . GLY A 1 947 ? 63.760 57.902 -25.651 1.00 9.59 ? 947 GLY A C 1 ATOM 7508 O O . GLY A 1 947 ? 62.836 57.139 -25.754 1.00 10.12 ? 947 GLY A O 1 ATOM 7509 N N . GLY A 1 948 ? 64.509 58.240 -26.723 1.00 11.09 ? 948 GLY A N 1 ATOM 7510 C CA . GLY A 1 948 ? 64.240 57.646 -28.014 1.00 11.57 ? 948 GLY A CA 1 ATOM 7511 C C . GLY A 1 948 ? 64.331 56.134 -28.034 1.00 11.89 ? 948 GLY A C 1 ATOM 7512 O O . GLY A 1 948 ? 63.697 55.530 -28.895 1.00 16.87 ? 948 GLY A O 1 ATOM 7513 N N . ASP A 1 949 ? 65.072 55.540 -27.101 1.00 12.35 ? 949 ASP A N 1 ATOM 7514 C CA . ASP A 1 949 ? 65.156 54.089 -27.018 1.00 16.10 ? 949 ASP A CA 1 ATOM 7515 C C . ASP A 1 949 ? 64.147 53.473 -26.033 1.00 13.82 ? 949 ASP A C 1 ATOM 7516 O O . ASP A 1 949 ? 64.152 52.251 -25.792 1.00 17.06 ? 949 ASP A O 1 ATOM 7517 C CB . ASP A 1 949 ? 66.598 53.657 -26.637 1.00 15.73 ? 949 ASP A CB 1 ATOM 7518 C CG . ASP A 1 949 ? 67.083 54.235 -25.316 1.00 22.81 ? 949 ASP A CG 1 ATOM 7519 O OD1 . ASP A 1 949 ? 66.502 55.186 -24.723 1.00 23.33 ? 949 ASP A OD1 1 ATOM 7520 O OD2 . ASP A 1 949 ? 68.136 53.738 -24.820 1.00 31.06 ? 949 ASP A OD2 1 ATOM 7521 N N . HIS A 1 950 ? 63.271 54.277 -25.420 1.00 11.50 ? 950 HIS A N 1 ATOM 7522 C CA . HIS A 1 950 ? 62.246 53.732 -24.510 1.00 10.11 ? 950 HIS A CA 1 ATOM 7523 C C . HIS A 1 950 ? 61.189 52.979 -25.331 1.00 9.74 ? 950 HIS A C 1 ATOM 7524 O O . HIS A 1 950 ? 60.813 53.452 -26.365 1.00 12.48 ? 950 HIS A O 1 ATOM 7525 C CB . HIS A 1 950 ? 61.531 54.862 -23.742 1.00 10.34 ? 950 HIS A CB 1 ATOM 7526 C CG . HIS A 1 950 ? 62.397 55.577 -22.758 1.00 9.27 ? 950 HIS A CG 1 ATOM 7527 N ND1 . HIS A 1 950 ? 62.013 56.743 -22.136 1.00 11.81 ? 950 HIS A ND1 1 ATOM 7528 C CD2 . HIS A 1 950 ? 63.629 55.291 -22.289 1.00 5.73 ? 950 HIS A CD2 1 ATOM 7529 C CE1 . HIS A 1 950 ? 62.970 57.141 -21.322 1.00 7.97 ? 950 HIS A CE1 1 ATOM 7530 N NE2 . HIS A 1 950 ? 63.967 56.279 -21.402 1.00 12.47 ? 950 HIS A NE2 1 ATOM 7531 N N . PRO A 1 951 ? 60.716 51.820 -24.864 1.00 10.74 ? 951 PRO A N 1 ATOM 7532 C CA . PRO A 1 951 ? 59.685 51.087 -25.590 1.00 10.92 ? 951 PRO A CA 1 ATOM 7533 C C . PRO A 1 951 ? 58.405 51.891 -25.710 1.00 10.78 ? 951 PRO A C 1 ATOM 7534 O O . PRO A 1 951 ? 58.000 52.575 -24.749 1.00 10.99 ? 951 PRO A O 1 ATOM 7535 C CB . PRO A 1 951 ? 59.437 49.830 -24.732 1.00 14.14 ? 951 PRO A CB 1 ATOM 7536 C CG . PRO A 1 951 ? 60.697 49.636 -24.035 1.00 16.52 ? 951 PRO A CG 1 ATOM 7537 C CD . PRO A 1 951 ? 61.185 51.082 -23.688 1.00 14.42 ? 951 PRO A CD 1 ATOM 7538 N N . SER A 1 952 ? 57.739 51.782 -26.842 1.00 10.26 ? 952 SER A N 1 ATOM 7539 C CA . SER A 1 952 ? 56.480 52.457 -27.077 1.00 9.79 ? 952 SER A CA 1 ATOM 7540 C C . SER A 1 952 ? 55.412 51.406 -26.881 1.00 10.08 ? 952 SER A C 1 ATOM 7541 O O . SER A 1 952 ? 55.170 50.563 -27.766 1.00 11.51 ? 952 SER A O 1 ATOM 7542 C CB . SER A 1 952 ? 56.453 53.043 -28.502 1.00 9.93 ? 952 SER A CB 1 ATOM 7543 O OG . SER A 1 952 ? 55.415 54.009 -28.659 1.00 11.06 ? 952 SER A OG 1 ATOM 7544 N N . ALA A 1 953 ? 54.761 51.448 -25.713 1.00 10.59 ? 953 ALA A N 1 ATOM 7545 C CA . ALA A 1 953 ? 53.815 50.424 -25.309 1.00 8.90 ? 953 ALA A CA 1 ATOM 7546 C C . ALA A 1 953 ? 52.446 50.543 -25.946 1.00 10.51 ? 953 ALA A C 1 ATOM 7547 O O . ALA A 1 953 ? 52.027 51.629 -26.388 1.00 10.22 ? 953 ALA A O 1 ATOM 7548 C CB . ALA A 1 953 ? 53.674 50.454 -23.784 1.00 11.68 ? 953 ALA A CB 1 ATOM 7549 N N . ARG A 1 954 ? 51.710 49.436 -25.968 1.00 8.87 ? 954 ARG A N 1 ATOM 7550 C CA . ARG A 1 954 ? 50.376 49.422 -26.526 1.00 9.86 ? 954 ARG A CA 1 ATOM 7551 C C . ARG A 1 954 ? 49.563 50.565 -25.875 1.00 9.00 ? 954 ARG A C 1 ATOM 7552 O O . ARG A 1 954 ? 49.697 50.847 -24.664 1.00 8.61 ? 954 ARG A O 1 ATOM 7553 C CB . ARG A 1 954 ? 49.738 48.057 -26.309 1.00 12.32 ? 954 ARG A CB 1 ATOM 7554 C CG . ARG A 1 954 ? 48.503 47.900 -27.260 1.00 15.83 ? 954 ARG A CG 1 ATOM 7555 C CD . ARG A 1 954 ? 47.981 46.466 -27.399 1.00 20.49 ? 954 ARG A CD 1 ATOM 7556 N NE . ARG A 1 954 ? 47.035 46.173 -26.349 1.00 20.59 ? 954 ARG A NE 1 ATOM 7557 C CZ . ARG A 1 954 ? 46.418 45.016 -26.208 1.00 33.83 ? 954 ARG A CZ 1 ATOM 7558 N NH1 . ARG A 1 954 ? 46.668 44.016 -27.062 1.00 37.82 ? 954 ARG A NH1 1 ATOM 7559 N NH2 . ARG A 1 954 ? 45.516 44.879 -25.249 1.00 26.55 ? 954 ARG A NH2 1 ATOM 7560 N N . GLU A 1 955 ? 48.627 51.127 -26.642 1.00 9.56 ? 955 GLU A N 1 ATOM 7561 C CA . GLU A 1 955 ? 47.930 52.339 -26.230 1.00 9.33 ? 955 GLU A CA 1 ATOM 7562 C C . GLU A 1 955 ? 47.114 52.199 -24.982 1.00 7.83 ? 955 GLU A C 1 ATOM 7563 O O . GLU A 1 955 ? 46.774 53.232 -24.354 1.00 10.14 ? 955 GLU A O 1 ATOM 7564 C CB . GLU A 1 955 ? 47.037 52.830 -27.393 1.00 13.20 ? 955 GLU A CB 1 ATOM 7565 C CG . GLU A 1 955 ? 45.916 51.853 -27.764 1.00 13.27 ? 955 GLU A CG 1 ATOM 7566 C CD . GLU A 1 955 ? 45.006 52.358 -28.838 1.00 19.51 ? 955 GLU A CD 1 ATOM 7567 O OE1 . GLU A 1 955 ? 44.739 53.577 -28.896 1.00 22.57 ? 955 GLU A OE1 1 ATOM 7568 O OE2 . GLU A 1 955 ? 44.503 51.521 -29.601 1.00 20.55 ? 955 GLU A OE2 1 ATOM 7569 N N . ASP A 1 956 ? 46.673 50.992 -24.652 1.00 7.57 ? 956 ASP A N 1 ATOM 7570 C CA . ASP A 1 956 ? 45.839 50.850 -23.432 1.00 9.39 ? 956 ASP A CA 1 ATOM 7571 C C . ASP A 1 956 ? 46.676 50.732 -22.170 1.00 7.35 ? 956 ASP A C 1 ATOM 7572 O O . ASP A 1 956 ? 46.079 50.653 -21.085 1.00 8.99 ? 956 ASP A O 1 ATOM 7573 C CB . ASP A 1 956 ? 44.864 49.645 -23.555 1.00 10.27 ? 956 ASP A CB 1 ATOM 7574 C CG . ASP A 1 956 ? 45.539 48.338 -23.935 1.00 10.78 ? 956 ASP A CG 1 ATOM 7575 O OD1 . ASP A 1 956 ? 46.749 48.243 -24.126 1.00 13.13 ? 956 ASP A OD1 1 ATOM 7576 O OD2 . ASP A 1 956 ? 44.776 47.340 -24.003 1.00 12.26 ? 956 ASP A OD2 1 ATOM 7577 N N . LEU A 1 957 ? 47.996 50.723 -22.270 1.00 7.79 ? 957 LEU A N 1 ATOM 7578 C CA . LEU A 1 957 ? 48.864 50.566 -21.075 1.00 8.51 ? 957 LEU A CA 1 ATOM 7579 C C . LEU A 1 957 ? 49.418 51.923 -20.665 1.00 8.28 ? 957 LEU A C 1 ATOM 7580 O O . LEU A 1 957 ? 49.837 52.723 -21.510 1.00 9.10 ? 957 LEU A O 1 ATOM 7581 C CB . LEU A 1 957 ? 50.044 49.638 -21.436 1.00 9.32 ? 957 LEU A CB 1 ATOM 7582 C CG . LEU A 1 957 ? 50.919 49.141 -20.286 1.00 13.70 ? 957 LEU A CG 1 ATOM 7583 C CD1 . LEU A 1 957 ? 50.064 48.265 -19.306 1.00 17.09 ? 957 LEU A CD1 1 ATOM 7584 C CD2 . LEU A 1 957 ? 52.040 48.241 -20.842 1.00 15.09 ? 957 LEU A CD2 1 ATOM 7585 N N . ASP A 1 958 ? 49.432 52.169 -19.366 1.00 7.29 ? 958 ASP A N 1 ATOM 7586 C CA . ASP A 1 958 ? 50.069 53.384 -18.840 1.00 7.04 ? 958 ASP A CA 1 ATOM 7587 C C . ASP A 1 958 ? 50.990 53.057 -17.698 1.00 6.69 ? 958 ASP A C 1 ATOM 7588 O O . ASP A 1 958 ? 50.755 52.096 -16.924 1.00 8.28 ? 958 ASP A O 1 ATOM 7589 C CB . ASP A 1 958 ? 49.012 54.364 -18.343 1.00 7.22 ? 958 ASP A CB 1 ATOM 7590 C CG . ASP A 1 958 ? 49.553 55.798 -18.150 1.00 8.23 ? 958 ASP A CG 1 ATOM 7591 O OD1 . ASP A 1 958 ? 50.654 56.109 -18.637 1.00 8.60 ? 958 ASP A OD1 1 ATOM 7592 O OD2 . ASP A 1 958 ? 48.827 56.583 -17.494 1.00 9.35 ? 958 ASP A OD2 1 ATOM 7593 N N . VAL A 1 959 ? 52.052 53.843 -17.561 1.00 6.65 ? 959 VAL A N 1 ATOM 7594 C CA . VAL A 1 959 ? 52.919 53.827 -16.367 1.00 6.24 ? 959 VAL A CA 1 ATOM 7595 C C . VAL A 1 959 ? 52.367 54.961 -15.510 1.00 6.54 ? 959 VAL A C 1 ATOM 7596 O O . VAL A 1 959 ? 52.781 56.125 -15.616 1.00 8.05 ? 959 VAL A O 1 ATOM 7597 C CB . VAL A 1 959 ? 54.402 54.055 -16.728 1.00 6.43 ? 959 VAL A CB 1 ATOM 7598 C CG1 . VAL A 1 959 ? 55.255 54.154 -15.425 1.00 7.42 ? 959 VAL A CG1 1 ATOM 7599 C CG2 . VAL A 1 959 ? 54.936 52.861 -17.578 1.00 8.82 ? 959 VAL A CG2 1 ATOM 7600 N N . SER A 1 960 ? 51.405 54.633 -14.663 1.00 7.11 ? 960 SER A N 1 ATOM 7601 C CA . SER A 1 960 ? 50.712 55.596 -13.831 1.00 7.39 ? 960 SER A CA 1 ATOM 7602 C C . SER A 1 960 ? 51.625 56.273 -12.866 1.00 7.62 ? 960 SER A C 1 ATOM 7603 O O . SER A 1 960 ? 51.438 57.489 -12.584 1.00 8.46 ? 960 SER A O 1 ATOM 7604 C CB . SER A 1 960 ? 49.598 54.921 -13.040 1.00 8.03 ? 960 SER A CB 1 ATOM 7605 O OG . SER A 1 960 ? 48.771 54.112 -13.913 1.00 9.56 ? 960 SER A OG 1 ATOM 7606 N N . VAL A 1 961 ? 52.597 55.534 -12.332 1.00 7.41 ? 961 VAL A N 1 ATOM 7607 C CA . VAL A 1 961 ? 53.562 56.076 -11.380 1.00 6.74 ? 961 VAL A CA 1 ATOM 7608 C C . VAL A 1 961 ? 54.944 55.498 -11.702 1.00 7.30 ? 961 VAL A C 1 ATOM 7609 O O . VAL A 1 961 ? 55.089 54.284 -11.977 1.00 6.43 ? 961 VAL A O 1 ATOM 7610 C CB . VAL A 1 961 ? 53.267 55.585 -9.923 1.00 7.37 ? 961 VAL A CB 1 ATOM 7611 C CG1 . VAL A 1 961 ? 54.419 56.037 -8.959 1.00 8.07 ? 961 VAL A CG1 1 ATOM 7612 C CG2 . VAL A 1 961 ? 51.941 56.145 -9.431 1.00 8.91 ? 961 VAL A CG2 1 ATOM 7613 N N . MET A 1 962 ? 55.943 56.376 -11.710 1.00 6.35 ? 962 MET A N 1 ATOM 7614 C CA . MET A 1 962 ? 57.340 55.991 -11.701 1.00 5.88 ? 962 MET A CA 1 ATOM 7615 C C . MET A 1 962 ? 57.943 56.793 -10.544 1.00 6.67 ? 962 MET A C 1 ATOM 7616 O O . MET A 1 962 ? 57.899 58.034 -10.556 1.00 7.83 ? 962 MET A O 1 ATOM 7617 C CB . MET A 1 962 ? 58.082 56.292 -13.018 1.00 7.96 ? 962 MET A CB 1 ATOM 7618 C CG . MET A 1 962 ? 59.583 55.936 -12.926 1.00 7.84 ? 962 MET A CG 1 ATOM 7619 S SD . MET A 1 962 ? 60.291 56.237 -14.570 1.00 8.96 ? 962 MET A SD 1 ATOM 7620 C CE . MET A 1 962 ? 62.070 55.776 -14.260 1.00 9.55 ? 962 MET A CE 1 ATOM 7621 N N . ARG A 1 963 ? 58.497 56.107 -9.549 1.00 6.71 ? 963 ARG A N 1 ATOM 7622 C CA . ARG A 1 963 ? 58.992 56.769 -8.355 1.00 6.17 ? 963 ARG A CA 1 ATOM 7623 C C . ARG A 1 963 ? 60.262 56.101 -7.836 1.00 6.73 ? 963 ARG A C 1 ATOM 7624 O O . ARG A 1 963 ? 60.216 54.925 -7.485 1.00 6.62 ? 963 ARG A O 1 ATOM 7625 C CB . ARG A 1 963 ? 57.924 56.733 -7.241 1.00 7.17 ? 963 ARG A CB 1 ATOM 7626 C CG . ARG A 1 963 ? 58.363 57.394 -5.895 1.00 8.03 ? 963 ARG A CG 1 ATOM 7627 C CD . ARG A 1 963 ? 57.283 57.265 -4.778 1.00 9.35 ? 963 ARG A CD 1 ATOM 7628 N NE . ARG A 1 963 ? 56.054 57.909 -5.224 1.00 8.94 ? 963 ARG A NE 1 ATOM 7629 C CZ . ARG A 1 963 ? 54.838 57.387 -5.180 1.00 8.66 ? 963 ARG A CZ 1 ATOM 7630 N NH1 . ARG A 1 963 ? 54.610 56.212 -4.622 1.00 9.27 ? 963 ARG A NH1 1 ATOM 7631 N NH2 . ARG A 1 963 ? 53.836 58.088 -5.694 1.00 8.88 ? 963 ARG A NH2 1 ATOM 7632 N N . ARG A 1 964 ? 61.369 56.857 -7.749 1.00 7.52 ? 964 ARG A N 1 ATOM 7633 C CA . ARG A 1 964 ? 62.554 56.236 -7.083 1.00 8.05 ? 964 ARG A CA 1 ATOM 7634 C C . ARG A 1 964 ? 62.252 56.209 -5.590 1.00 7.78 ? 964 ARG A C 1 ATOM 7635 O O . ARG A 1 964 ? 61.841 57.175 -4.999 1.00 8.74 ? 964 ARG A O 1 ATOM 7636 C CB . ARG A 1 964 ? 63.774 57.094 -7.408 1.00 7.76 ? 964 ARG A CB 1 ATOM 7637 C CG . ARG A 1 964 ? 65.036 56.423 -6.793 1.00 8.76 ? 964 ARG A CG 1 ATOM 7638 C CD . ARG A 1 964 ? 66.343 57.080 -7.283 1.00 8.78 ? 964 ARG A CD 1 ATOM 7639 N NE . ARG A 1 964 ? 66.559 56.950 -8.701 1.00 9.02 ? 964 ARG A NE 1 ATOM 7640 C CZ . ARG A 1 964 ? 67.419 56.156 -9.292 1.00 8.96 ? 964 ARG A CZ 1 ATOM 7641 N NH1 . ARG A 1 964 ? 68.192 55.362 -8.524 1.00 13.32 ? 964 ARG A NH1 1 ATOM 7642 N NH2 . ARG A 1 964 ? 67.521 56.102 -10.618 1.00 12.56 ? 964 ARG A NH2 1 ATOM 7643 N N . LEU A 1 965 ? 62.504 55.049 -4.992 1.00 7.56 ? 965 LEU A N 1 ATOM 7644 C CA . LEU A 1 965 ? 62.122 54.761 -3.603 1.00 7.08 ? 965 LEU A CA 1 ATOM 7645 C C . LEU A 1 965 ? 63.289 54.891 -2.609 1.00 9.16 ? 965 LEU A C 1 ATOM 7646 O O . LEU A 1 965 ? 63.058 54.849 -1.401 1.00 10.84 ? 965 LEU A O 1 ATOM 7647 C CB . LEU A 1 965 ? 61.590 53.339 -3.514 1.00 9.16 ? 965 LEU A CB 1 ATOM 7648 C CG . LEU A 1 965 ? 60.343 53.109 -4.390 1.00 7.99 ? 965 LEU A CG 1 ATOM 7649 C CD1 . LEU A 1 965 ? 59.960 51.603 -4.340 1.00 9.87 ? 965 LEU A CD1 1 ATOM 7650 C CD2 . LEU A 1 965 ? 59.158 53.997 -3.948 1.00 11.13 ? 965 LEU A CD2 1 ATOM 7651 N N . THR A 1 966 ? 64.504 55.044 -3.145 1.00 9.16 ? 966 THR A N 1 ATOM 7652 C CA . THR A 1 966 ? 65.728 55.150 -2.327 1.00 9.04 ? 966 THR A CA 1 ATOM 7653 C C . THR A 1 966 ? 66.419 56.480 -2.509 1.00 9.18 ? 966 THR A C 1 ATOM 7654 O O . THR A 1 966 ? 66.411 57.042 -3.612 1.00 10.33 ? 966 THR A O 1 ATOM 7655 C CB . THR A 1 966 ? 66.746 54.071 -2.724 1.00 9.65 ? 966 THR A CB 1 ATOM 7656 O OG1 . THR A 1 966 ? 66.783 53.952 -4.130 1.00 9.95 ? 966 THR A OG1 1 ATOM 7657 C CG2 . THR A 1 966 ? 66.348 52.704 -2.113 1.00 11.94 ? 966 THR A CG2 1 ATOM 7658 N N . LYS A 1 967 ? 67.066 56.961 -1.448 1.00 10.10 ? 967 LYS A N 1 ATOM 7659 C CA . LYS A 1 967 ? 67.887 58.172 -1.491 1.00 10.23 ? 967 LYS A CA 1 ATOM 7660 C C . LYS A 1 967 ? 69.276 57.727 -1.996 1.00 10.61 ? 967 LYS A C 1 ATOM 7661 O O . LYS A 1 967 ? 69.564 56.524 -2.153 1.00 10.86 ? 967 LYS A O 1 ATOM 7662 C CB . LYS A 1 967 ? 68.038 58.791 -0.102 1.00 12.60 ? 967 LYS A CB 1 ATOM 7663 C CG . LYS A 1 967 ? 66.670 59.305 0.408 1.00 16.55 ? 967 LYS A CG 1 ATOM 7664 C CD . LYS A 1 967 ? 66.828 60.208 1.633 1.00 21.24 ? 967 LYS A CD 1 ATOM 7665 C CE . LYS A 1 967 ? 65.507 60.907 1.939 1.00 28.66 ? 967 LYS A CE 1 ATOM 7666 N NZ . LYS A 1 967 ? 65.655 61.660 3.216 1.00 35.29 ? 967 LYS A NZ 1 ATOM 7667 N N . SER A 1 968 ? 70.105 58.728 -2.320 1.00 11.51 ? 968 SER A N 1 ATOM 7668 C CA . SER A 1 968 ? 71.404 58.429 -2.977 1.00 11.65 ? 968 SER A CA 1 ATOM 7669 C C . SER A 1 968 ? 72.387 57.636 -2.128 1.00 12.10 ? 968 SER A C 1 ATOM 7670 O O . SER A 1 968 ? 73.235 56.975 -2.727 1.00 16.30 ? 968 SER A O 1 ATOM 7671 C CB . SER A 1 968 ? 72.105 59.731 -3.453 1.00 14.85 ? 968 SER A CB 1 ATOM 7672 O OG . SER A 1 968 ? 72.426 60.545 -2.373 1.00 20.69 ? 968 SER A OG 1 ATOM 7673 N N . SER A 1 969 ? 72.206 57.631 -0.818 1.00 12.93 ? 969 SER A N 1 ATOM 7674 C CA . SER A 1 969 ? 73.146 56.842 0.020 1.00 13.66 ? 969 SER A CA 1 ATOM 7675 C C . SER A 1 969 ? 72.921 55.330 0.009 1.00 14.53 ? 969 SER A C 1 ATOM 7676 O O . SER A 1 969 ? 73.759 54.582 0.524 1.00 14.75 ? 969 SER A O 1 ATOM 7677 C CB . SER A 1 969 ? 73.101 57.387 1.447 1.00 19.92 ? 969 SER A CB 1 ATOM 7678 O OG . SER A 1 969 ? 71.774 57.290 1.932 1.00 29.17 ? 969 SER A OG 1 ATOM 7679 N N . ALA A 1 970 ? 71.814 54.852 -0.553 1.00 11.85 ? 970 ALA A N 1 ATOM 7680 C CA . ALA A 1 970 ? 71.531 53.444 -0.606 1.00 11.12 ? 970 ALA A CA 1 ATOM 7681 C C . ALA A 1 970 ? 72.358 52.735 -1.645 1.00 12.81 ? 970 ALA A C 1 ATOM 7682 O O . ALA A 1 970 ? 72.339 53.052 -2.846 1.00 14.71 ? 970 ALA A O 1 ATOM 7683 C CB . ALA A 1 970 ? 70.026 53.193 -0.883 1.00 13.87 ? 970 ALA A CB 1 ATOM 7684 N N . LYS A 1 971 ? 73.085 51.690 -1.204 1.00 13.60 ? 971 LYS A N 1 ATOM 7685 C CA . LYS A 1 971 ? 73.886 50.905 -2.113 1.00 14.47 ? 971 LYS A CA 1 ATOM 7686 C C . LYS A 1 971 ? 73.032 50.275 -3.202 1.00 14.12 ? 971 LYS A C 1 ATOM 7687 O O . LYS A 1 971 ? 73.428 50.241 -4.366 1.00 16.19 ? 971 LYS A O 1 ATOM 7688 C CB . LYS A 1 971 ? 74.619 49.797 -1.298 1.00 16.69 ? 971 LYS A CB 1 ATOM 7689 C CG . LYS A 1 971 ? 75.489 48.884 -2.098 1.00 22.97 ? 971 LYS A CG 1 ATOM 7690 C CD . LYS A 1 971 ? 76.433 48.088 -1.131 1.00 26.48 ? 971 LYS A CD 1 ATOM 7691 C CE . LYS A 1 971 ? 77.237 47.057 -1.908 1.00 33.40 ? 971 LYS A CE 1 ATOM 7692 N NZ . LYS A 1 971 ? 77.919 47.629 -3.113 1.00 39.04 ? 971 LYS A NZ 1 ATOM 7693 N N . THR A 1 972 ? 71.865 49.752 -2.794 1.00 13.57 ? 972 THR A N 1 ATOM 7694 C CA . THR A 1 972 ? 70.999 49.144 -3.788 1.00 13.06 ? 972 THR A CA 1 ATOM 7695 C C . THR A 1 972 ? 69.841 50.152 -4.043 1.00 11.28 ? 972 THR A C 1 ATOM 7696 O O . THR A 1 972 ? 69.049 50.413 -3.152 1.00 13.13 ? 972 THR A O 1 ATOM 7697 C CB . THR A 1 972 ? 70.430 47.779 -3.328 1.00 17.58 ? 972 THR A CB 1 ATOM 7698 O OG1 . THR A 1 972 ? 71.531 46.865 -3.149 1.00 18.69 ? 972 THR A OG1 1 ATOM 7699 C CG2 . THR A 1 972 ? 69.501 47.151 -4.402 1.00 17.51 ? 972 THR A CG2 1 ATOM 7700 N N . GLN A 1 973 ? 69.794 50.711 -5.233 1.00 10.98 ? 973 GLN A N 1 ATOM 7701 C CA . GLN A 1 973 ? 68.735 51.652 -5.593 1.00 10.27 ? 973 GLN A CA 1 ATOM 7702 C C . GLN A 1 973 ? 67.460 50.891 -5.953 1.00 10.94 ? 973 GLN A C 1 ATOM 7703 O O . GLN A 1 973 ? 67.514 49.810 -6.509 1.00 11.81 ? 973 GLN A O 1 ATOM 7704 C CB . GLN A 1 973 ? 69.189 52.534 -6.757 1.00 10.29 ? 973 GLN A CB 1 ATOM 7705 C CG . GLN A 1 973 ? 70.263 53.543 -6.356 1.00 10.08 ? 973 GLN A CG 1 ATOM 7706 C CD . GLN A 1 973 ? 69.759 54.598 -5.378 1.00 10.89 ? 973 GLN A CD 1 ATOM 7707 O OE1 . GLN A 1 973 ? 68.772 55.270 -5.635 1.00 12.30 ? 973 GLN A OE1 1 ATOM 7708 N NE2 . GLN A 1 973 ? 70.444 54.748 -4.264 1.00 8.11 ? 973 GLN A NE2 1 ATOM 7709 N N . ARG A 1 974 ? 66.317 51.484 -5.610 1.00 10.25 ? 974 ARG A N 1 ATOM 7710 C CA . ARG A 1 974 ? 65.046 50.864 -5.928 1.00 10.30 ? 974 ARG A CA 1 ATOM 7711 C C . ARG A 1 974 ? 64.126 51.858 -6.606 1.00 7.79 ? 974 ARG A C 1 ATOM 7712 O O . ARG A 1 974 ? 64.031 52.997 -6.136 1.00 9.03 ? 974 ARG A O 1 ATOM 7713 C CB . ARG A 1 974 ? 64.356 50.349 -4.691 1.00 10.43 ? 974 ARG A CB 1 ATOM 7714 C CG . ARG A 1 974 ? 65.211 49.258 -3.958 1.00 12.28 ? 974 ARG A CG 1 ATOM 7715 C CD . ARG A 1 974 ? 64.661 49.007 -2.552 1.00 15.50 ? 974 ARG A CD 1 ATOM 7716 N NE . ARG A 1 974 ? 63.469 48.180 -2.614 1.00 21.60 ? 974 ARG A NE 1 ATOM 7717 C CZ . ARG A 1 974 ? 62.274 48.507 -2.128 1.00 18.72 ? 974 ARG A CZ 1 ATOM 7718 N NH1 . ARG A 1 974 ? 62.056 49.650 -1.517 1.00 19.52 ? 974 ARG A NH1 1 ATOM 7719 N NH2 . ARG A 1 974 ? 61.283 47.640 -2.274 1.00 16.90 ? 974 ARG A NH2 1 ATOM 7720 N N . VAL A 1 975 ? 63.471 51.404 -7.660 1.00 9.34 ? 975 VAL A N 1 ATOM 7721 C CA . VAL A 1 975 ? 62.511 52.272 -8.389 1.00 8.06 ? 975 VAL A CA 1 ATOM 7722 C C . VAL A 1 975 ? 61.203 51.518 -8.503 1.00 9.33 ? 975 VAL A C 1 ATOM 7723 O O . VAL A 1 975 ? 61.158 50.341 -8.946 1.00 8.92 ? 975 VAL A O 1 ATOM 7724 C CB . VAL A 1 975 ? 63.014 52.627 -9.814 1.00 9.56 ? 975 VAL A CB 1 ATOM 7725 C CG1 . VAL A 1 975 ? 62.031 53.609 -10.522 1.00 9.07 ? 975 VAL A CG1 1 ATOM 7726 C CG2 . VAL A 1 975 ? 64.376 53.390 -9.693 1.00 12.90 ? 975 VAL A CG2 1 ATOM 7727 N N . GLY A 1 976 ? 60.128 52.208 -8.115 1.00 8.44 ? 976 GLY A N 1 ATOM 7728 C CA . GLY A 1 976 ? 58.786 51.620 -8.168 1.00 7.44 ? 976 GLY A CA 1 ATOM 7729 C C . GLY A 1 976 ? 57.963 52.100 -9.358 1.00 6.80 ? 976 GLY A C 1 ATOM 7730 O O . GLY A 1 976 ? 58.030 53.297 -9.749 1.00 7.59 ? 976 GLY A O 1 ATOM 7731 N N . TYR A 1 977 ? 57.192 51.202 -9.928 1.00 6.74 ? 977 TYR A N 1 ATOM 7732 C CA . TYR A 1 977 ? 56.319 51.516 -11.049 1.00 5.60 ? 977 TYR A CA 1 ATOM 7733 C C . TYR A 1 977 ? 54.922 50.972 -10.773 1.00 6.21 ? 977 TYR A C 1 ATOM 7734 O O . TYR A 1 977 ? 54.769 49.832 -10.272 1.00 7.29 ? 977 TYR A O 1 ATOM 7735 C CB . TYR A 1 977 ? 56.793 50.815 -12.338 1.00 7.98 ? 977 TYR A CB 1 ATOM 7736 C CG . TYR A 1 977 ? 58.175 51.155 -12.747 1.00 6.84 ? 977 TYR A CG 1 ATOM 7737 C CD1 . TYR A 1 977 ? 59.259 50.450 -12.246 1.00 8.70 ? 977 TYR A CD1 1 ATOM 7738 C CD2 . TYR A 1 977 ? 58.408 52.221 -13.625 1.00 9.39 ? 977 TYR A CD2 1 ATOM 7739 C CE1 . TYR A 1 977 ? 60.574 50.821 -12.655 1.00 9.38 ? 977 TYR A CE1 1 ATOM 7740 C CE2 . TYR A 1 977 ? 59.671 52.573 -14.008 1.00 9.03 ? 977 TYR A CE2 1 ATOM 7741 C CZ . TYR A 1 977 ? 60.745 51.870 -13.530 1.00 7.94 ? 977 TYR A CZ 1 ATOM 7742 O OH . TYR A 1 977 ? 62.035 52.252 -13.944 1.00 10.65 ? 977 TYR A OH 1 ATOM 7743 N N . VAL A 1 978 ? 53.901 51.785 -11.071 1.00 6.04 ? 978 VAL A N 1 ATOM 7744 C CA . VAL A 1 978 ? 52.529 51.288 -11.067 1.00 5.82 ? 978 VAL A CA 1 ATOM 7745 C C . VAL A 1 978 ? 52.107 51.235 -12.563 1.00 6.32 ? 978 VAL A C 1 ATOM 7746 O O . VAL A 1 978 ? 52.176 52.269 -13.278 1.00 7.32 ? 978 VAL A O 1 ATOM 7747 C CB . VAL A 1 978 ? 51.546 52.185 -10.248 1.00 7.27 ? 978 VAL A CB 1 ATOM 7748 C CG1 . VAL A 1 978 ? 50.097 51.693 -10.431 1.00 8.39 ? 978 VAL A CG1 1 ATOM 7749 C CG2 . VAL A 1 978 ? 51.938 52.189 -8.793 1.00 7.85 ? 978 VAL A CG2 1 ATOM 7750 N N . LEU A 1 979 ? 51.697 50.055 -13.006 1.00 7.15 ? 979 LEU A N 1 ATOM 7751 C CA . LEU A 1 979 ? 51.291 49.825 -14.390 1.00 8.11 ? 979 LEU A CA 1 ATOM 7752 C C . LEU A 1 979 ? 49.799 49.582 -14.429 1.00 8.61 ? 979 LEU A C 1 ATOM 7753 O O . LEU A 1 979 ? 49.279 48.716 -13.707 1.00 11.30 ? 979 LEU A O 1 ATOM 7754 C CB . LEU A 1 979 ? 52.036 48.590 -14.920 1.00 12.84 ? 979 LEU A CB 1 ATOM 7755 C CG A LEU A 1 979 ? 52.076 48.301 -16.416 0.50 16.01 ? 979 LEU A CG 1 ATOM 7756 C CG B LEU A 1 979 ? 53.324 48.910 -15.801 0.50 29.44 ? 979 LEU A CG 1 ATOM 7757 C CD1 A LEU A 1 979 ? 52.916 49.435 -17.014 0.50 20.85 ? 979 LEU A CD1 1 ATOM 7758 C CD1 B LEU A 1 979 ? 52.995 49.024 -17.269 0.50 27.64 ? 979 LEU A CD1 1 ATOM 7759 C CD2 A LEU A 1 979 ? 52.710 46.931 -16.754 0.50 19.45 ? 979 LEU A CD2 1 ATOM 7760 C CD2 B LEU A 1 979 ? 54.044 50.138 -15.303 0.50 27.74 ? 979 LEU A CD2 1 ATOM 7761 N N . HIS A 1 980 ? 49.068 50.341 -15.236 1.00 8.18 ? 980 HIS A N 1 ATOM 7762 C CA . HIS A 1 980 ? 47.625 50.156 -15.375 1.00 8.79 ? 980 HIS A CA 1 ATOM 7763 C C . HIS A 1 980 ? 47.261 49.898 -16.822 1.00 8.78 ? 980 HIS A C 1 ATOM 7764 O O . HIS A 1 980 ? 47.728 50.594 -17.705 1.00 10.69 ? 980 HIS A O 1 ATOM 7765 C CB . HIS A 1 980 ? 46.866 51.407 -14.913 1.00 8.71 ? 980 HIS A CB 1 ATOM 7766 C CG . HIS A 1 980 ? 45.390 51.287 -15.097 1.00 9.32 ? 980 HIS A CG 1 ATOM 7767 N ND1 . HIS A 1 980 ? 44.628 50.414 -14.359 1.00 12.80 ? 980 HIS A ND1 1 ATOM 7768 C CD2 . HIS A 1 980 ? 44.558 51.852 -15.996 1.00 6.04 ? 980 HIS A CD2 1 ATOM 7769 C CE1 . HIS A 1 980 ? 43.374 50.487 -14.763 1.00 7.34 ? 980 HIS A CE1 1 ATOM 7770 N NE2 . HIS A 1 980 ? 43.309 51.341 -15.766 1.00 13.88 ? 980 HIS A NE2 1 ATOM 7771 N N . ARG A 1 981 ? 46.428 48.893 -17.060 1.00 6.93 ? 981 ARG A N 1 ATOM 7772 C CA . ARG A 1 981 ? 45.926 48.685 -18.415 1.00 7.93 ? 981 ARG A CA 1 ATOM 7773 C C . ARG A 1 981 ? 44.438 48.904 -18.392 1.00 6.32 ? 981 ARG A C 1 ATOM 7774 O O . ARG A 1 981 ? 43.735 48.284 -17.592 1.00 8.56 ? 981 ARG A O 1 ATOM 7775 C CB A ARG A 1 981 ? 46.197 47.268 -18.891 0.50 8.89 ? 981 ARG A CB 1 ATOM 7776 C CB B ARG A 1 981 ? 46.290 47.357 -19.062 0.50 9.11 ? 981 ARG A CB 1 ATOM 7777 C CG A ARG A 1 981 ? 45.843 47.092 -20.367 0.50 12.92 ? 981 ARG A CG 1 ATOM 7778 C CG B ARG A 1 981 ? 46.090 47.372 -20.619 0.50 13.02 ? 981 ARG A CG 1 ATOM 7779 C CD A ARG A 1 981 ? 46.269 45.715 -20.882 0.50 22.77 ? 981 ARG A CD 1 ATOM 7780 C CD B ARG A 1 981 ? 46.059 45.967 -21.282 0.50 24.71 ? 981 ARG A CD 1 ATOM 7781 N NE A ARG A 1 981 ? 46.869 45.899 -22.175 0.50 35.02 ? 981 ARG A NE 1 ATOM 7782 N NE B ARG A 1 981 ? 47.288 45.219 -21.063 0.50 28.35 ? 981 ARG A NE 1 ATOM 7783 C CZ A ARG A 1 981 ? 48.118 45.563 -22.480 0.50 26.33 ? 981 ARG A CZ 1 ATOM 7784 C CZ B ARG A 1 981 ? 48.346 45.261 -21.872 0.50 25.75 ? 981 ARG A CZ 1 ATOM 7785 N NH1 A ARG A 1 981 ? 48.924 44.989 -21.583 0.50 27.33 ? 981 ARG A NH1 1 ATOM 7786 N NH1 B ARG A 1 981 ? 48.334 46.030 -22.969 0.50 28.53 ? 981 ARG A NH1 1 ATOM 7787 N NH2 A ARG A 1 981 ? 48.573 45.856 -23.676 0.50 24.09 ? 981 ARG A NH2 1 ATOM 7788 N NH2 B ARG A 1 981 ? 49.413 44.501 -21.607 0.50 25.05 ? 981 ARG A NH2 1 ATOM 7789 N N . THR A 1 982 ? 43.965 49.830 -19.216 1.00 7.54 ? 982 THR A N 1 ATOM 7790 C CA . THR A 1 982 ? 42.498 50.009 -19.301 1.00 7.08 ? 982 THR A CA 1 ATOM 7791 C C . THR A 1 982 ? 41.971 48.955 -20.326 1.00 8.65 ? 982 THR A C 1 ATOM 7792 O O . THR A 1 982 ? 42.705 48.035 -20.699 1.00 11.44 ? 982 THR A O 1 ATOM 7793 C CB . THR A 1 982 ? 42.189 51.477 -19.749 1.00 8.04 ? 982 THR A CB 1 ATOM 7794 O OG1 . THR A 1 982 ? 40.780 51.731 -19.579 1.00 8.71 ? 982 THR A OG1 1 ATOM 7795 C CG2 . THR A 1 982 ? 42.659 51.776 -21.213 1.00 9.55 ? 982 THR A CG2 1 ATOM 7796 N N . ASN A 1 983 ? 40.696 49.056 -20.665 1.00 7.72 ? 983 ASN A N 1 ATOM 7797 C CA . ASN A 1 983 ? 40.155 48.159 -21.704 1.00 6.99 ? 983 ASN A CA 1 ATOM 7798 C C . ASN A 1 983 ? 39.430 49.054 -22.725 1.00 7.92 ? 983 ASN A C 1 ATOM 7799 O O . ASN A 1 983 ? 38.547 49.812 -22.346 1.00 9.60 ? 983 ASN A O 1 ATOM 7800 C CB . ASN A 1 983 ? 39.160 47.138 -21.106 1.00 7.74 ? 983 ASN A CB 1 ATOM 7801 C CG . ASN A 1 983 ? 38.676 46.171 -22.151 1.00 7.72 ? 983 ASN A CG 1 ATOM 7802 O OD1 . ASN A 1 983 ? 39.408 45.270 -22.546 1.00 10.98 ? 983 ASN A OD1 1 ATOM 7803 N ND2 . ASN A 1 983 ? 37.479 46.416 -22.656 1.00 9.69 ? 983 ASN A ND2 1 ATOM 7804 N N . LEU A 1 984 ? 39.864 48.915 -23.965 1.00 8.26 ? 984 LEU A N 1 ATOM 7805 C CA . LEU A 1 984 ? 39.309 49.710 -25.087 1.00 8.27 ? 984 LEU A CA 1 ATOM 7806 C C . LEU A 1 984 ? 38.511 48.845 -25.991 1.00 11.06 ? 984 LEU A C 1 ATOM 7807 O O . LEU A 1 984 ? 38.822 47.673 -26.186 1.00 11.87 ? 984 LEU A O 1 ATOM 7808 C CB . LEU A 1 984 ? 40.457 50.359 -25.853 1.00 9.88 ? 984 LEU A CB 1 ATOM 7809 C CG . LEU A 1 984 ? 41.357 51.256 -24.985 1.00 10.87 ? 984 LEU A CG 1 ATOM 7810 C CD1 . LEU A 1 984 ? 42.544 51.725 -25.905 1.00 12.50 ? 984 LEU A CD1 1 ATOM 7811 C CD2 . LEU A 1 984 ? 40.577 52.410 -24.357 1.00 10.74 ? 984 LEU A CD2 1 ATOM 7812 N N . MET A 1 985 ? 37.455 49.380 -26.561 1.00 10.76 ? 985 MET A N 1 ATOM 7813 C CA . MET A 1 985 ? 36.627 48.572 -27.439 1.00 13.97 ? 985 MET A CA 1 ATOM 7814 C C . MET A 1 985 ? 37.313 48.194 -28.720 1.00 16.85 ? 985 MET A C 1 ATOM 7815 O O . MET A 1 985 ? 38.065 48.955 -29.271 1.00 17.10 ? 985 MET A O 1 ATOM 7816 C CB . MET A 1 985 ? 35.342 49.299 -27.730 1.00 16.71 ? 985 MET A CB 1 ATOM 7817 C CG . MET A 1 985 ? 34.481 49.412 -26.529 1.00 17.89 ? 985 MET A CG 1 ATOM 7818 S SD . MET A 1 985 ? 32.751 49.477 -27.011 1.00 20.41 ? 985 MET A SD 1 ATOM 7819 C CE . MET A 1 985 ? 32.769 51.086 -27.797 1.00 19.92 ? 985 MET A CE 1 ATOM 7820 N N . GLN A 1 986 ? 37.023 46.989 -29.182 1.00 18.47 ? 986 GLN A N 1 ATOM 7821 C CA . GLN A 1 986 ? 37.433 46.514 -30.491 1.00 18.87 ? 986 GLN A CA 1 ATOM 7822 C C . GLN A 1 986 ? 36.411 47.010 -31.489 1.00 17.91 ? 986 GLN A C 1 ATOM 7823 O O . GLN A 1 986 ? 35.265 46.616 -31.408 1.00 16.98 ? 986 GLN A O 1 ATOM 7824 C CB . GLN A 1 986 ? 37.396 44.989 -30.515 1.00 24.57 ? 986 GLN A CB 1 ATOM 7825 C CG . GLN A 1 986 ? 38.293 44.319 -29.527 1.00 30.09 ? 986 GLN A CG 1 ATOM 7826 C CD . GLN A 1 986 ? 39.716 44.265 -29.992 1.00 36.53 ? 986 GLN A CD 1 ATOM 7827 O OE1 . GLN A 1 986 ? 40.004 44.232 -31.189 1.00 41.15 ? 986 GLN A OE1 1 ATOM 7828 N NE2 . GLN A 1 986 ? 40.624 44.292 -29.049 1.00 35.57 ? 986 GLN A NE2 1 ATOM 7829 N N . CYS A 1 987 ? 36.818 47.870 -32.406 1.00 15.04 ? 987 CYS A N 1 ATOM 7830 C CA . CYS A 1 987 ? 35.859 48.362 -33.403 1.00 16.78 ? 987 CYS A CA 1 ATOM 7831 C C . CYS A 1 987 ? 36.345 48.182 -34.853 1.00 19.06 ? 987 CYS A C 1 ATOM 7832 O O . CYS A 1 987 ? 35.849 48.863 -35.755 1.00 22.26 ? 987 CYS A O 1 ATOM 7833 C CB . CYS A 1 987 ? 35.521 49.829 -33.165 1.00 17.60 ? 987 CYS A CB 1 ATOM 7834 S SG . CYS A 1 987 ? 34.947 50.218 -31.453 1.00 19.69 ? 987 CYS A SG 1 ATOM 7835 N N . GLY A 1 988 ? 37.284 47.285 -35.081 1.00 17.99 ? 988 GLY A N 1 ATOM 7836 C CA . GLY A 1 988 ? 37.689 47.075 -36.473 1.00 23.17 ? 988 GLY A CA 1 ATOM 7837 C C . GLY A 1 988 ? 38.959 47.736 -36.952 1.00 26.77 ? 988 GLY A C 1 ATOM 7838 O O . GLY A 1 988 ? 39.284 47.639 -38.147 1.00 25.47 ? 988 GLY A O 1 ATOM 7839 N N . THR A 1 989 ? 39.671 48.431 -36.073 1.00 23.05 ? 989 THR A N 1 ATOM 7840 C CA . THR A 1 989 ? 40.939 49.033 -36.477 1.00 25.92 ? 989 THR A CA 1 ATOM 7841 C C . THR A 1 989 ? 42.068 48.042 -36.258 1.00 29.34 ? 989 THR A C 1 ATOM 7842 O O . THR A 1 989 ? 42.274 47.554 -35.133 1.00 26.00 ? 989 THR A O 1 ATOM 7843 C CB . THR A 1 989 ? 41.241 50.255 -35.678 1.00 25.10 ? 989 THR A CB 1 ATOM 7844 O OG1 . THR A 1 989 ? 40.117 51.140 -35.742 1.00 32.30 ? 989 THR A OG1 1 ATOM 7845 C CG2 . THR A 1 989 ? 42.469 50.936 -36.264 1.00 26.93 ? 989 THR A CG2 1 ATOM 7846 N N . PRO A 1 990 ? 42.853 47.749 -37.284 1.00 29.99 ? 990 PRO A N 1 ATOM 7847 C CA . PRO A 1 990 ? 44.010 46.878 -37.065 1.00 34.54 ? 990 PRO A CA 1 ATOM 7848 C C . PRO A 1 990 ? 44.912 47.290 -35.890 1.00 37.55 ? 990 PRO A C 1 ATOM 7849 O O . PRO A 1 990 ? 45.442 46.384 -35.259 1.00 38.59 ? 990 PRO A O 1 ATOM 7850 C CB . PRO A 1 990 ? 44.745 46.944 -38.398 1.00 35.01 ? 990 PRO A CB 1 ATOM 7851 C CG . PRO A 1 990 ? 43.658 47.119 -39.389 1.00 35.00 ? 990 PRO A CG 1 ATOM 7852 C CD . PRO A 1 990 ? 42.615 47.986 -38.718 1.00 31.27 ? 990 PRO A CD 1 ATOM 7853 N N . GLU A 1 991 ? 45.049 48.583 -35.578 1.00 39.33 ? 991 GLU A N 1 ATOM 7854 C CA . GLU A 1 991 ? 45.933 49.046 -34.496 1.00 46.72 ? 991 GLU A CA 1 ATOM 7855 C C . GLU A 1 991 ? 46.997 48.029 -34.080 1.00 47.97 ? 991 GLU A C 1 ATOM 7856 O O . GLU A 1 991 ? 46.685 47.027 -33.439 1.00 51.01 ? 991 GLU A O 1 ATOM 7857 C CB . GLU A 1 991 ? 45.159 49.498 -33.240 1.00 47.04 ? 991 GLU A CB 1 ATOM 7858 C CG . GLU A 1 991 ? 43.923 50.357 -33.464 1.00 49.24 ? 991 GLU A CG 1 ATOM 7859 C CD . GLU A 1 991 ? 43.535 51.152 -32.228 1.00 50.47 ? 991 GLU A CD 1 ATOM 7860 O OE1 . GLU A 1 991 ? 42.920 50.575 -31.305 1.00 53.01 ? 991 GLU A OE1 1 ATOM 7861 O OE2 . GLU A 1 991 ? 43.842 52.357 -32.185 1.00 45.84 ? 991 GLU A OE2 1 ATOM 7862 N N . GLU A 1 992 ? 48.254 48.317 -34.409 1.00 45.27 ? 992 GLU A N 1 ATOM 7863 C CA . GLU A 1 992 ? 49.274 47.279 -34.572 1.00 46.21 ? 992 GLU A CA 1 ATOM 7864 C C . GLU A 1 992 ? 50.605 47.594 -33.874 1.00 42.16 ? 992 GLU A C 1 ATOM 7865 O O . GLU A 1 992 ? 50.612 48.059 -32.750 1.00 37.25 ? 992 GLU A O 1 ATOM 7866 C CB . GLU A 1 992 ? 49.499 47.004 -36.053 1.00 49.62 ? 992 GLU A CB 1 ATOM 7867 C CG . GLU A 1 992 ? 48.250 46.508 -36.757 1.00 49.63 ? 992 GLU A CG 1 ATOM 7868 C CD . GLU A 1 992 ? 48.001 45.035 -36.501 1.00 52.45 ? 992 GLU A CD 1 ATOM 7869 O OE1 . GLU A 1 992 ? 48.663 44.468 -35.612 1.00 54.57 ? 992 GLU A OE1 1 ATOM 7870 O OE2 . GLU A 1 992 ? 47.151 44.442 -37.189 1.00 51.84 ? 992 GLU A OE2 1 ATOM 7871 N N . HIS A 1 993 ? 51.719 47.352 -34.570 1.00 41.01 ? 993 HIS A N 1 ATOM 7872 C CA . HIS A 1 993 ? 53.078 47.330 -33.991 1.00 40.43 ? 993 HIS A CA 1 ATOM 7873 C C . HIS A 1 993 ? 53.354 48.236 -32.795 1.00 37.25 ? 993 HIS A C 1 ATOM 7874 O O . HIS A 1 993 ? 53.476 49.457 -32.922 1.00 36.83 ? 993 HIS A O 1 ATOM 7875 C CB . HIS A 1 993 ? 54.108 47.645 -35.073 1.00 41.27 ? 993 HIS A CB 1 ATOM 7876 C CG . HIS A 1 993 ? 53.656 48.698 -36.026 1.00 44.27 ? 993 HIS A CG 1 ATOM 7877 N ND1 . HIS A 1 993 ? 53.380 48.439 -37.349 1.00 47.45 ? 993 HIS A ND1 1 ATOM 7878 C CD2 . HIS A 1 993 ? 53.390 50.011 -35.835 1.00 45.72 ? 993 HIS A CD2 1 ATOM 7879 C CE1 . HIS A 1 993 ? 52.990 49.553 -37.940 1.00 47.81 ? 993 HIS A CE1 1 ATOM 7880 N NE2 . HIS A 1 993 ? 52.976 50.519 -37.039 1.00 44.54 ? 993 HIS A NE2 1 ATOM 7881 N N . THR A 1 994 ? 53.506 47.605 -31.638 1.00 33.76 ? 994 THR A N 1 ATOM 7882 C CA . THR A 1 994 ? 54.060 48.231 -30.449 1.00 27.58 ? 994 THR A CA 1 ATOM 7883 C C . THR A 1 994 ? 55.075 47.287 -29.793 1.00 27.37 ? 994 THR A C 1 ATOM 7884 O O . THR A 1 994 ? 55.177 46.132 -30.159 1.00 25.86 ? 994 THR A O 1 ATOM 7885 C CB . THR A 1 994 ? 52.936 48.534 -29.446 1.00 23.33 ? 994 THR A CB 1 ATOM 7886 O OG1 . THR A 1 994 ? 52.282 47.313 -29.081 1.00 23.91 ? 994 THR A OG1 1 ATOM 7887 C CG2 . THR A 1 994 ? 51.915 49.449 -30.086 1.00 22.36 ? 994 THR A CG2 1 ATOM 7888 N N . GLN A 1 995 ? 55.815 47.779 -28.811 1.00 20.01 ? 995 GLN A N 1 ATOM 7889 C CA . GLN A 1 995 ? 56.844 46.964 -28.183 1.00 18.11 ? 995 GLN A CA 1 ATOM 7890 C C . GLN A 1 995 ? 56.436 46.609 -26.759 1.00 14.73 ? 995 GLN A C 1 ATOM 7891 O O . GLN A 1 995 ? 55.740 47.372 -26.105 1.00 16.62 ? 995 GLN A O 1 ATOM 7892 C CB . GLN A 1 995 ? 58.167 47.724 -28.175 1.00 16.98 ? 995 GLN A CB 1 ATOM 7893 C CG . GLN A 1 995 ? 58.569 48.228 -29.550 1.00 24.64 ? 995 GLN A CG 1 ATOM 7894 C CD . GLN A 1 995 ? 59.373 49.512 -29.517 1.00 31.18 ? 995 GLN A CD 1 ATOM 7895 O OE1 . GLN A 1 995 ? 58.881 50.560 -29.125 1.00 19.78 ? 995 GLN A OE1 1 ATOM 7896 N NE2 . GLN A 1 995 ? 60.620 49.431 -29.952 1.00 35.52 ? 995 GLN A NE2 1 ATOM 7897 N N . LYS A 1 996 ? 56.873 45.454 -26.280 1.00 15.47 ? 996 LYS A N 1 ATOM 7898 C CA . LYS A 1 996 ? 56.564 45.069 -24.918 1.00 15.47 ? 996 LYS A CA 1 ATOM 7899 C C . LYS A 1 996 ? 57.300 46.032 -23.988 1.00 15.08 ? 996 LYS A C 1 ATOM 7900 O O . LYS A 1 996 ? 58.478 46.376 -24.206 1.00 15.89 ? 996 LYS A O 1 ATOM 7901 C CB . LYS A 1 996 ? 57.037 43.596 -24.689 1.00 20.39 ? 996 LYS A CB 1 ATOM 7902 C CG . LYS A 1 996 ? 56.977 43.087 -23.252 1.00 27.61 ? 996 LYS A CG 1 ATOM 7903 C CD . LYS A 1 996 ? 57.261 41.556 -23.265 1.00 30.86 ? 996 LYS A CD 1 ATOM 7904 C CE . LYS A 1 996 ? 57.400 40.969 -21.846 1.00 32.33 ? 996 LYS A CE 1 ATOM 7905 N NZ . LYS A 1 996 ? 57.774 39.519 -22.002 1.00 42.60 ? 996 LYS A NZ 1 ATOM 7906 N N . LEU A 1 997 ? 56.578 46.454 -22.940 1.00 14.12 ? 997 LEU A N 1 ATOM 7907 C CA . LEU A 1 997 ? 57.208 47.312 -21.956 1.00 13.59 ? 997 LEU A CA 1 ATOM 7908 C C . LEU A 1 997 ? 57.517 46.476 -20.732 1.00 11.65 ? 997 LEU A C 1 ATOM 7909 O O . LEU A 1 997 ? 56.594 45.937 -20.113 1.00 15.44 ? 997 LEU A O 1 ATOM 7910 C CB . LEU A 1 997 ? 56.219 48.422 -21.573 1.00 15.49 ? 997 LEU A CB 1 ATOM 7911 C CG . LEU A 1 997 ? 56.675 49.310 -20.412 1.00 16.86 ? 997 LEU A CG 1 ATOM 7912 C CD1 . LEU A 1 997 ? 57.973 50.028 -20.734 1.00 20.06 ? 997 LEU A CD1 1 ATOM 7913 C CD2 . LEU A 1 997 ? 55.587 50.319 -20.131 1.00 19.98 ? 997 LEU A CD2 1 ATOM 7914 N N . ASP A 1 998 ? 58.808 46.424 -20.428 1.00 11.86 ? 998 ASP A N 1 ATOM 7915 C CA . ASP A 1 998 ? 59.303 45.755 -19.203 1.00 13.36 ? 998 ASP A CA 1 ATOM 7916 C C . ASP A 1 998 ? 59.885 46.888 -18.343 1.00 12.31 ? 998 ASP A C 1 ATOM 7917 O O . ASP A 1 998 ? 61.033 47.332 -18.528 1.00 12.53 ? 998 ASP A O 1 ATOM 7918 C CB . ASP A 1 998 ? 60.391 44.708 -19.555 1.00 13.42 ? 998 ASP A CB 1 ATOM 7919 C CG . ASP A 1 998 ? 61.090 44.192 -18.343 1.00 16.97 ? 998 ASP A CG 1 ATOM 7920 O OD1 . ASP A 1 998 ? 60.621 44.442 -17.210 1.00 15.36 ? 998 ASP A OD1 1 ATOM 7921 O OD2 . ASP A 1 998 ? 62.110 43.518 -18.550 1.00 16.93 ? 998 ASP A OD2 1 ATOM 7922 N N . VAL A 1 999 ? 59.089 47.327 -17.358 1.00 12.12 ? 999 VAL A N 1 ATOM 7923 C CA . VAL A 1 999 ? 59.582 48.448 -16.567 1.00 12.03 ? 999 VAL A CA 1 ATOM 7924 C C . VAL A 1 999 ? 60.841 48.133 -15.779 1.00 11.45 ? 999 VAL A C 1 ATOM 7925 O O . VAL A 1 999 ? 61.630 49.020 -15.471 1.00 12.53 ? 999 VAL A O 1 ATOM 7926 C CB . VAL A 1 999 ? 58.497 49.021 -15.569 1.00 11.03 ? 999 VAL A CB 1 ATOM 7927 C CG1 . VAL A 1 999 ? 57.350 49.611 -16.377 1.00 12.98 ? 999 VAL A CG1 1 ATOM 7928 C CG2 . VAL A 1 999 ? 58.014 47.958 -14.607 1.00 12.06 ? 999 VAL A CG2 1 ATOM 7929 N N . CYS A 1 1000 ? 61.090 46.851 -15.489 1.00 11.65 ? 1000 CYS A N 1 ATOM 7930 C CA . CYS A 1 1000 ? 62.281 46.560 -14.718 1.00 13.85 ? 1000 CYS A CA 1 ATOM 7931 C C . CYS A 1 1000 ? 63.584 46.772 -15.445 1.00 12.74 ? 1000 CYS A C 1 ATOM 7932 O O . CYS A 1 1000 ? 64.620 46.816 -14.814 1.00 15.42 ? 1000 CYS A O 1 ATOM 7933 C CB . CYS A 1 1000 ? 62.160 45.158 -14.138 1.00 15.41 ? 1000 CYS A CB 1 ATOM 7934 S SG . CYS A 1 1000 ? 61.178 45.176 -12.540 1.00 18.75 ? 1000 CYS A SG 1 ATOM 7935 N N . HIS A 1 1001 ? 63.516 46.901 -16.788 1.00 13.12 ? 1001 HIS A N 1 ATOM 7936 C CA . HIS A 1 1001 ? 64.733 47.135 -17.562 1.00 14.30 ? 1001 HIS A CA 1 ATOM 7937 C C . HIS A 1 1001 ? 64.797 48.572 -18.084 1.00 15.46 ? 1001 HIS A C 1 ATOM 7938 O O . HIS A 1 1001 ? 65.617 48.893 -18.948 1.00 17.91 ? 1001 HIS A O 1 ATOM 7939 C CB . HIS A 1 1001 ? 64.871 46.079 -18.676 1.00 14.26 ? 1001 HIS A CB 1 ATOM 7940 C CG . HIS A 1 1001 ? 65.419 44.775 -18.180 1.00 15.83 ? 1001 HIS A CG 1 ATOM 7941 N ND1 . HIS A 1 1001 ? 64.619 43.739 -17.766 1.00 17.23 ? 1001 HIS A ND1 1 ATOM 7942 C CD2 . HIS A 1 1001 ? 66.699 44.361 -17.991 1.00 17.83 ? 1001 HIS A CD2 1 ATOM 7943 C CE1 . HIS A 1 1001 ? 65.373 42.728 -17.353 1.00 18.06 ? 1001 HIS A CE1 1 ATOM 7944 N NE2 . HIS A 1 1001 ? 66.640 43.078 -17.473 1.00 18.45 ? 1001 HIS A NE2 1 ATOM 7945 N N . LEU A 1 1002 ? 63.946 49.467 -17.592 1.00 13.71 ? 1002 LEU A N 1 ATOM 7946 C CA . LEU A 1 1002 ? 64.046 50.857 -18.039 1.00 12.99 ? 1002 LEU A CA 1 ATOM 7947 C C . LEU A 1 1002 ? 65.304 51.529 -17.479 1.00 15.55 ? 1002 LEU A C 1 ATOM 7948 O O . LEU A 1 1002 ? 65.805 52.507 -18.070 1.00 17.84 ? 1002 LEU A O 1 ATOM 7949 C CB . LEU A 1 1002 ? 62.830 51.697 -17.561 1.00 13.63 ? 1002 LEU A CB 1 ATOM 7950 C CG . LEU A 1 1002 ? 61.567 51.467 -18.377 1.00 12.01 ? 1002 LEU A CG 1 ATOM 7951 C CD1 . LEU A 1 1002 ? 60.395 52.177 -17.690 1.00 13.36 ? 1002 LEU A CD1 1 ATOM 7952 C CD2 . LEU A 1 1002 ? 61.685 52.037 -19.792 1.00 16.02 ? 1002 LEU A CD2 1 ATOM 7953 N N . LEU A 1 1003 ? 65.805 51.096 -16.327 1.00 14.92 ? 1003 LEU A N 1 ATOM 7954 C CA . LEU A 1 1003 ? 67.041 51.646 -15.771 1.00 14.66 ? 1003 LEU A CA 1 ATOM 7955 C C . LEU A 1 1003 ? 68.107 50.543 -15.901 1.00 16.62 ? 1003 LEU A C 1 ATOM 7956 O O . LEU A 1 1003 ? 67.792 49.354 -15.843 1.00 17.30 ? 1003 LEU A O 1 ATOM 7957 C CB . LEU A 1 1003 ? 66.855 52.047 -14.313 1.00 14.75 ? 1003 LEU A CB 1 ATOM 7958 C CG . LEU A 1 1003 ? 66.076 53.350 -14.257 1.00 20.31 ? 1003 LEU A CG 1 ATOM 7959 C CD1 . LEU A 1 1003 ? 65.562 53.494 -12.852 1.00 20.14 ? 1003 LEU A CD1 1 ATOM 7960 C CD2 . LEU A 1 1003 ? 66.931 54.526 -14.674 1.00 23.67 ? 1003 LEU A CD2 1 ATOM 7961 N N . PRO A 1 1004 ? 69.367 50.934 -16.076 1.00 17.42 ? 1004 PRO A N 1 ATOM 7962 C CA . PRO A 1 1004 ? 70.384 49.895 -16.221 1.00 15.73 ? 1004 PRO A CA 1 ATOM 7963 C C . PRO A 1 1004 ? 70.813 49.232 -14.919 1.00 17.21 ? 1004 PRO A C 1 ATOM 7964 O O . PRO A 1 1004 ? 70.452 49.598 -13.782 1.00 16.53 ? 1004 PRO A O 1 ATOM 7965 C CB . PRO A 1 1004 ? 71.537 50.664 -16.895 1.00 19.61 ? 1004 PRO A CB 1 ATOM 7966 C CG . PRO A 1 1004 ? 71.442 52.002 -16.236 1.00 20.61 ? 1004 PRO A CG 1 ATOM 7967 C CD . PRO A 1 1004 ? 69.933 52.284 -16.093 1.00 18.44 ? 1004 PRO A CD 1 ATOM 7968 N N . ASN A 1 1005 ? 71.557 48.155 -15.128 1.00 18.81 ? 1005 ASN A N 1 ATOM 7969 C CA . ASN A 1 1005 ? 72.125 47.406 -14.017 1.00 18.64 ? 1005 ASN A CA 1 ATOM 7970 C C . ASN A 1 1005 ? 71.091 46.820 -13.066 1.00 16.43 ? 1005 ASN A C 1 ATOM 7971 O O . ASN A 1 1005 ? 71.287 46.859 -11.853 1.00 16.45 ? 1005 ASN A O 1 ATOM 7972 C CB . ASN A 1 1005 ? 73.085 48.304 -13.221 1.00 21.65 ? 1005 ASN A CB 1 ATOM 7973 C CG . ASN A 1 1005 ? 74.121 48.985 -14.119 1.00 27.17 ? 1005 ASN A CG 1 ATOM 7974 O OD1 . ASN A 1 1005 ? 74.309 50.211 -14.052 1.00 35.21 ? 1005 ASN A OD1 1 ATOM 7975 N ND2 . ASN A 1 1005 ? 74.769 48.201 -14.963 1.00 25.13 ? 1005 ASN A ND2 1 ATOM 7976 N N . VAL A 1 1006 ? 70.039 46.253 -13.631 1.00 16.84 ? 1006 VAL A N 1 ATOM 7977 C CA . VAL A 1 1006 ? 69.003 45.678 -12.796 1.00 16.85 ? 1006 VAL A CA 1 ATOM 7978 C C . VAL A 1 1006 ? 69.530 44.374 -12.145 1.00 15.78 ? 1006 VAL A C 1 ATOM 7979 O O . VAL A 1 1006 ? 70.126 43.523 -12.816 1.00 20.15 ? 1006 VAL A O 1 ATOM 7980 C CB . VAL A 1 1006 ? 67.673 45.460 -13.609 1.00 17.53 ? 1006 VAL A CB 1 ATOM 7981 C CG1 . VAL A 1 1006 ? 67.823 44.433 -14.682 1.00 18.82 ? 1006 VAL A CG1 1 ATOM 7982 C CG2 . VAL A 1 1006 ? 66.572 45.000 -12.649 1.00 17.42 ? 1006 VAL A CG2 1 ATOM 7983 N N . ALA A 1 1007 ? 69.296 44.237 -10.853 1.00 12.79 ? 1007 ALA A N 1 ATOM 7984 C CA . ALA A 1 1007 ? 69.736 43.082 -10.054 1.00 14.77 ? 1007 ALA A CA 1 ATOM 7985 C C . ALA A 1 1007 ? 68.555 42.252 -9.576 1.00 18.95 ? 1007 ALA A C 1 ATOM 7986 O O . ALA A 1 1007 ? 68.707 41.052 -9.290 1.00 20.21 ? 1007 ALA A O 1 ATOM 7987 C CB . ALA A 1 1007 ? 70.549 43.605 -8.857 1.00 15.94 ? 1007 ALA A CB 1 ATOM 7988 N N . ARG A 1 1008 ? 67.359 42.849 -9.517 1.00 15.89 ? 1008 ARG A N 1 ATOM 7989 C CA . ARG A 1 1008 ? 66.163 42.135 -9.051 1.00 14.16 ? 1008 ARG A CA 1 ATOM 7990 C C . ARG A 1 1008 ? 64.912 42.864 -9.530 1.00 13.50 ? 1008 ARG A C 1 ATOM 7991 O O . ARG A 1 1008 ? 64.964 44.106 -9.708 1.00 14.32 ? 1008 ARG A O 1 ATOM 7992 C CB . ARG A 1 1008 ? 66.171 42.142 -7.534 1.00 16.35 ? 1008 ARG A CB 1 ATOM 7993 C CG . ARG A 1 1008 ? 65.129 41.280 -6.849 1.00 24.22 ? 1008 ARG A CG 1 ATOM 7994 C CD . ARG A 1 1008 ? 65.314 41.314 -5.333 1.00 29.14 ? 1008 ARG A CD 1 ATOM 7995 N NE . ARG A 1 1008 ? 64.597 40.214 -4.679 1.00 36.65 ? 1008 ARG A NE 1 ATOM 7996 C CZ . ARG A 1 1008 ? 65.055 38.956 -4.553 1.00 40.13 ? 1008 ARG A CZ 1 ATOM 7997 N NH1 . ARG A 1 1008 ? 66.258 38.600 -5.018 1.00 40.83 ? 1008 ARG A NH1 1 ATOM 7998 N NH2 . ARG A 1 1008 ? 64.282 38.023 -3.988 1.00 37.37 ? 1008 ARG A NH2 1 ATOM 7999 N N . CYS A 1 1009 ? 63.838 42.132 -9.775 1.00 11.89 ? 1009 CYS A N 1 ATOM 8000 C CA . CYS A 1 1009 ? 62.551 42.753 -10.161 1.00 11.84 ? 1009 CYS A CA 1 ATOM 8001 C C . CYS A 1 1009 ? 61.520 42.021 -9.297 1.00 13.53 ? 1009 CYS A C 1 ATOM 8002 O O . CYS A 1 1009 ? 61.461 40.766 -9.326 1.00 13.56 ? 1009 CYS A O 1 ATOM 8003 C CB . CYS A 1 1009 ? 62.280 42.515 -11.635 1.00 13.42 ? 1009 CYS A CB 1 ATOM 8004 S SG . CYS A 1 1009 ? 60.698 43.210 -12.283 1.00 19.71 ? 1009 CYS A SG 1 ATOM 8005 N N . GLU A 1 1010 ? 60.696 42.754 -8.522 1.00 11.95 ? 1010 GLU A N 1 ATOM 8006 C CA . GLU A 1 1010 ? 59.684 42.154 -7.679 1.00 10.71 ? 1010 GLU A CA 1 ATOM 8007 C C . GLU A 1 1010 ? 58.312 42.761 -7.985 1.00 9.48 ? 1010 GLU A C 1 ATOM 8008 O O . GLU A 1 1010 ? 58.209 43.989 -8.263 1.00 11.29 ? 1010 GLU A O 1 ATOM 8009 C CB . GLU A 1 1010 ? 59.946 42.509 -6.221 1.00 13.12 ? 1010 GLU A CB 1 ATOM 8010 C CG . GLU A 1 1010 ? 61.155 41.873 -5.561 1.00 19.46 ? 1010 GLU A CG 1 ATOM 8011 C CD . GLU A 1 1010 ? 60.895 40.439 -5.126 1.00 23.31 ? 1010 GLU A CD 1 ATOM 8012 O OE1 . GLU A 1 1010 ? 59.744 40.083 -4.723 1.00 31.06 ? 1010 GLU A OE1 1 ATOM 8013 O OE2 . GLU A 1 1010 ? 61.874 39.659 -5.167 1.00 33.69 ? 1010 GLU A OE2 1 ATOM 8014 N N . ARG A 1 1011 ? 57.275 41.955 -7.995 1.00 10.18 ? 1011 ARG A N 1 ATOM 8015 C CA . ARG A 1 1011 ? 55.892 42.486 -8.049 1.00 8.70 ? 1011 ARG A CA 1 ATOM 8016 C C . ARG A 1 1011 ? 55.549 42.804 -6.589 1.00 9.66 ? 1011 ARG A C 1 ATOM 8017 O O . ARG A 1 1011 ? 55.862 41.995 -5.672 1.00 10.68 ? 1011 ARG A O 1 ATOM 8018 C CB . ARG A 1 1011 ? 54.926 41.457 -8.585 1.00 11.05 ? 1011 ARG A CB 1 ATOM 8019 C CG . ARG A 1 1011 ? 53.540 42.088 -8.813 1.00 13.97 ? 1011 ARG A CG 1 ATOM 8020 C CD . ARG A 1 1011 ? 52.628 41.223 -9.597 1.00 16.30 ? 1011 ARG A CD 1 ATOM 8021 N NE . ARG A 1 1011 ? 52.343 40.041 -8.815 1.00 18.70 ? 1011 ARG A NE 1 ATOM 8022 C CZ . ARG A 1 1011 ? 51.444 39.950 -7.819 1.00 24.51 ? 1011 ARG A CZ 1 ATOM 8023 N NH1 . ARG A 1 1011 ? 50.700 40.999 -7.437 1.00 26.82 ? 1011 ARG A NH1 1 ATOM 8024 N NH2 . ARG A 1 1011 ? 51.253 38.779 -7.210 1.00 25.98 ? 1011 ARG A NH2 1 ATOM 8025 N N . THR A 1 1012 ? 54.946 43.960 -6.309 1.00 8.63 ? 1012 THR A N 1 ATOM 8026 C CA . THR A 1 1012 ? 54.612 44.373 -4.960 1.00 6.90 ? 1012 THR A CA 1 ATOM 8027 C C . THR A 1 1012 ? 53.151 44.812 -4.869 1.00 8.01 ? 1012 THR A C 1 ATOM 8028 O O . THR A 1 1012 ? 52.457 44.952 -5.884 1.00 8.18 ? 1012 THR A O 1 ATOM 8029 C CB . THR A 1 1012 ? 55.504 45.595 -4.549 1.00 8.65 ? 1012 THR A CB 1 ATOM 8030 O OG1 . THR A 1 1012 ? 55.181 46.742 -5.380 1.00 8.87 ? 1012 THR A OG1 1 ATOM 8031 C CG2 . THR A 1 1012 ? 57.000 45.331 -4.747 1.00 9.02 ? 1012 THR A CG2 1 ATOM 8032 N N . THR A 1 1013 ? 52.716 45.029 -3.643 1.00 7.70 ? 1013 THR A N 1 ATOM 8033 C CA . THR A 1 1013 ? 51.451 45.712 -3.440 1.00 7.46 ? 1013 THR A CA 1 ATOM 8034 C C . THR A 1 1013 ? 51.562 47.120 -4.100 1.00 7.49 ? 1013 THR A C 1 ATOM 8035 O O . THR A 1 1013 ? 52.661 47.650 -4.331 1.00 7.19 ? 1013 THR A O 1 ATOM 8036 C CB . THR A 1 1013 ? 51.153 45.867 -1.970 1.00 7.76 ? 1013 THR A CB 1 ATOM 8037 O OG1 . THR A 1 1013 ? 52.331 46.310 -1.293 1.00 8.53 ? 1013 THR A OG1 1 ATOM 8038 C CG2 . THR A 1 1013 ? 50.666 44.505 -1.382 1.00 10.58 ? 1013 THR A CG2 1 ATOM 8039 N N . LEU A 1 1014 ? 50.399 47.750 -4.335 1.00 6.92 ? 1014 LEU A N 1 ATOM 8040 C CA . LEU A 1 1014 ? 50.423 49.052 -5.069 1.00 6.50 ? 1014 LEU A CA 1 ATOM 8041 C C . LEU A 1 1014 ? 51.099 50.196 -4.342 1.00 6.29 ? 1014 LEU A C 1 ATOM 8042 O O . LEU A 1 1014 ? 51.454 51.195 -4.959 1.00 7.60 ? 1014 LEU A O 1 ATOM 8043 C CB . LEU A 1 1014 ? 48.992 49.510 -5.453 1.00 7.75 ? 1014 LEU A CB 1 ATOM 8044 C CG . LEU A 1 1014 ? 48.264 48.536 -6.375 1.00 6.75 ? 1014 LEU A CG 1 ATOM 8045 C CD1 . LEU A 1 1014 ? 46.966 49.249 -6.733 1.00 8.34 ? 1014 LEU A CD1 1 ATOM 8046 C CD2 . LEU A 1 1014 ? 49.070 48.136 -7.655 1.00 8.21 ? 1014 LEU A CD2 1 ATOM 8047 N N . THR A 1 1015 ? 51.267 50.069 -3.018 1.00 6.48 ? 1015 THR A N 1 ATOM 8048 C CA . THR A 1 1015 ? 51.926 51.036 -2.178 1.00 6.28 ? 1015 THR A CA 1 ATOM 8049 C C . THR A 1 1015 ? 53.452 50.797 -2.125 1.00 6.67 ? 1015 THR A C 1 ATOM 8050 O O . THR A 1 1015 ? 54.174 51.570 -1.482 1.00 7.43 ? 1015 THR A O 1 ATOM 8051 C CB . THR A 1 1015 ? 51.414 50.934 -0.746 1.00 6.70 ? 1015 THR A CB 1 ATOM 8052 O OG1 . THR A 1 1015 ? 51.604 49.525 -0.383 1.00 7.20 ? 1015 THR A OG1 1 ATOM 8053 C CG2 . THR A 1 1015 ? 49.954 51.314 -0.611 1.00 7.72 ? 1015 THR A CG2 1 ATOM 8054 N N . PHE A 1 1016 ? 53.916 49.732 -2.800 1.00 6.88 ? 1016 PHE A N 1 ATOM 8055 C CA . PHE A 1 1016 ? 55.338 49.269 -2.839 1.00 7.90 ? 1016 PHE A CA 1 ATOM 8056 C C . PHE A 1 1016 ? 55.796 48.698 -1.500 1.00 8.44 ? 1016 PHE A C 1 ATOM 8057 O O . PHE A 1 1016 ? 57.002 48.394 -1.377 1.00 10.69 ? 1016 PHE A O 1 ATOM 8058 C CB . PHE A 1 1016 ? 56.296 50.392 -3.277 1.00 8.81 ? 1016 PHE A CB 1 ATOM 8059 C CG . PHE A 1 1016 ? 55.927 51.023 -4.581 1.00 7.43 ? 1016 PHE A CG 1 ATOM 8060 C CD1 . PHE A 1 1016 ? 55.798 50.259 -5.736 1.00 8.39 ? 1016 PHE A CD1 1 ATOM 8061 C CD2 . PHE A 1 1016 ? 55.756 52.415 -4.648 1.00 7.93 ? 1016 PHE A CD2 1 ATOM 8062 C CE1 . PHE A 1 1016 ? 55.494 50.906 -6.960 1.00 8.49 ? 1016 PHE A CE1 1 ATOM 8063 C CE2 . PHE A 1 1016 ? 55.453 53.019 -5.878 1.00 7.63 ? 1016 PHE A CE2 1 ATOM 8064 C CZ . PHE A 1 1016 ? 55.325 52.263 -7.011 1.00 8.81 ? 1016 PHE A CZ 1 ATOM 8065 N N . LEU A 1 1017 ? 54.905 48.469 -0.534 1.00 7.56 ? 1017 LEU A N 1 ATOM 8066 C CA . LEU A 1 1017 ? 55.349 48.115 0.825 1.00 8.64 ? 1017 LEU A CA 1 ATOM 8067 C C . LEU A 1 1017 ? 55.512 46.639 1.058 1.00 9.69 ? 1017 LEU A C 1 ATOM 8068 O O . LEU A 1 1017 ? 56.135 46.303 2.085 1.00 14.45 ? 1017 LEU A O 1 ATOM 8069 C CB . LEU A 1 1017 ? 54.399 48.734 1.860 1.00 8.59 ? 1017 LEU A CB 1 ATOM 8070 C CG . LEU A 1 1017 ? 54.382 50.254 1.785 1.00 8.62 ? 1017 LEU A CG 1 ATOM 8071 C CD1 . LEU A 1 1017 ? 53.336 50.785 2.747 1.00 10.01 ? 1017 LEU A CD1 1 ATOM 8072 C CD2 . LEU A 1 1017 ? 55.722 50.892 2.181 1.00 11.33 ? 1017 LEU A CD2 1 ATOM 8073 N N . GLN A 1 1018 ? 55.015 45.765 0.212 1.00 8.44 ? 1018 GLN A N 1 ATOM 8074 C CA . GLN A 1 1018 ? 55.229 44.334 0.412 1.00 10.17 ? 1018 GLN A CA 1 ATOM 8075 C C . GLN A 1 1018 ? 55.579 43.654 -0.897 1.00 10.35 ? 1018 GLN A C 1 ATOM 8076 O O . GLN A 1 1018 ? 54.952 43.878 -1.903 1.00 10.36 ? 1018 GLN A O 1 ATOM 8077 C CB . GLN A 1 1018 ? 53.975 43.692 1.008 1.00 11.59 ? 1018 GLN A CB 1 ATOM 8078 C CG . GLN A 1 1018 ? 54.132 42.198 1.237 1.00 15.69 ? 1018 GLN A CG 1 ATOM 8079 C CD . GLN A 1 1018 ? 52.869 41.490 1.705 1.00 22.43 ? 1018 GLN A CD 1 ATOM 8080 O OE1 . GLN A 1 1018 ? 51.781 42.047 1.729 1.00 24.62 ? 1018 GLN A OE1 1 ATOM 8081 N NE2 . GLN A 1 1018 ? 53.016 40.216 2.030 1.00 18.37 ? 1018 GLN A NE2 1 ATOM 8082 N N . ASN A 1 1019 ? 56.591 42.803 -0.871 1.00 11.16 ? 1019 ASN A N 1 ATOM 8083 C CA . ASN A 1 1019 ? 56.965 42.062 -2.073 1.00 12.49 ? 1019 ASN A CA 1 ATOM 8084 C C . ASN A 1 1019 ? 56.063 40.840 -2.174 1.00 14.32 ? 1019 ASN A C 1 ATOM 8085 O O . ASN A 1 1019 ? 55.898 40.102 -1.162 1.00 16.77 ? 1019 ASN A O 1 ATOM 8086 C CB . ASN A 1 1019 ? 58.432 41.592 -2.002 1.00 15.50 ? 1019 ASN A CB 1 ATOM 8087 C CG . ASN A 1 1019 ? 59.418 42.745 -1.960 1.00 18.76 ? 1019 ASN A CG 1 ATOM 8088 O OD1 . ASN A 1 1019 ? 59.184 43.827 -2.534 1.00 16.17 ? 1019 ASN A OD1 1 ATOM 8089 N ND2 . ASN A 1 1019 ? 60.571 42.527 -1.293 1.00 21.24 ? 1019 ASN A ND2 1 ATOM 8090 N N . LEU A 1 1020 ? 55.459 40.631 -3.336 1.00 12.55 ? 1020 LEU A N 1 ATOM 8091 C CA . LEU A 1 1020 ? 54.547 39.536 -3.559 1.00 14.50 ? 1020 LEU A CA 1 ATOM 8092 C C . LEU A 1 1020 ? 55.108 38.449 -4.471 1.00 15.66 ? 1020 LEU A C 1 ATOM 8093 O O . LEU A 1 1020 ? 54.632 37.299 -4.427 1.00 17.72 ? 1020 LEU A O 1 ATOM 8094 C CB . LEU A 1 1020 ? 53.239 40.041 -4.181 1.00 15.91 ? 1020 LEU A CB 1 ATOM 8095 C CG . LEU A 1 1020 ? 52.518 41.147 -3.369 1.00 14.16 ? 1020 LEU A CG 1 ATOM 8096 C CD1 . LEU A 1 1020 ? 51.321 41.687 -4.184 1.00 17.50 ? 1020 LEU A CD1 1 ATOM 8097 C CD2 . LEU A 1 1020 ? 51.982 40.590 -2.050 1.00 16.49 ? 1020 LEU A CD2 1 ATOM 8098 N N . GLU A 1 1021 ? 56.058 38.781 -5.321 1.00 13.72 ? 1021 GLU A N 1 ATOM 8099 C CA . GLU A 1 1021 ? 56.591 37.779 -6.277 1.00 17.25 ? 1021 GLU A CA 1 ATOM 8100 C C . GLU A 1 1021 ? 57.967 38.187 -6.768 1.00 18.04 ? 1021 GLU A C 1 ATOM 8101 O O . GLU A 1 1021 ? 58.184 39.347 -7.154 1.00 16.51 ? 1021 GLU A O 1 ATOM 8102 C CB . GLU A 1 1021 ? 55.627 37.702 -7.475 1.00 18.79 ? 1021 GLU A CB 1 ATOM 8103 C CG . GLU A 1 1021 ? 55.887 36.619 -8.517 1.00 26.90 ? 1021 GLU A CG 1 ATOM 8104 C CD . GLU A 1 1021 ? 54.911 36.706 -9.706 1.00 28.93 ? 1021 GLU A CD 1 ATOM 8105 O OE1 . GLU A 1 1021 ? 53.998 37.586 -9.740 1.00 29.99 ? 1021 GLU A OE1 1 ATOM 8106 O OE2 . GLU A 1 1021 ? 55.079 35.882 -10.632 1.00 35.93 ? 1021 GLU A OE2 1 ATOM 8107 N N . HIS A 1 1022 ? 58.931 37.263 -6.772 1.00 19.83 ? 1022 HIS A N 1 ATOM 8108 C CA . HIS A 1 1022 ? 60.282 37.505 -7.279 1.00 19.94 ? 1022 HIS A CA 1 ATOM 8109 C C . HIS A 1 1022 ? 60.169 37.084 -8.746 1.00 20.67 ? 1022 HIS A C 1 ATOM 8110 O O . HIS A 1 1022 ? 59.753 35.957 -9.045 1.00 23.10 ? 1022 HIS A O 1 ATOM 8111 C CB . HIS A 1 1022 ? 61.258 36.597 -6.516 1.00 23.48 ? 1022 HIS A CB 1 ATOM 8112 C CG . HIS A 1 1022 ? 62.694 36.871 -6.818 1.00 30.53 ? 1022 HIS A CG 1 ATOM 8113 N ND1 . HIS A 1 1022 ? 63.682 35.925 -6.634 1.00 36.46 ? 1022 HIS A ND1 1 ATOM 8114 C CD2 . HIS A 1 1022 ? 63.318 37.982 -7.290 1.00 33.89 ? 1022 HIS A CD2 1 ATOM 8115 C CE1 . HIS A 1 1022 ? 64.852 36.437 -6.986 1.00 37.31 ? 1022 HIS A CE1 1 ATOM 8116 N NE2 . HIS A 1 1022 ? 64.659 37.685 -7.387 1.00 38.29 ? 1022 HIS A NE2 1 ATOM 8117 N N . LEU A 1 1023 ? 60.532 37.963 -9.668 1.00 14.43 ? 1023 LEU A N 1 ATOM 8118 C CA . LEU A 1 1023 ? 60.306 37.732 -11.078 1.00 17.59 ? 1023 LEU A CA 1 ATOM 8119 C C . LEU A 1 1023 ? 61.459 37.188 -11.868 1.00 16.25 ? 1023 LEU A C 1 ATOM 8120 O O . LEU A 1 1023 ? 62.563 37.755 -11.861 1.00 18.57 ? 1023 LEU A O 1 ATOM 8121 C CB . LEU A 1 1023 ? 59.853 39.054 -11.686 1.00 17.13 ? 1023 LEU A CB 1 ATOM 8122 C CG . LEU A 1 1023 ? 58.514 39.506 -11.073 1.00 18.10 ? 1023 LEU A CG 1 ATOM 8123 C CD1 . LEU A 1 1023 ? 58.289 40.977 -11.312 1.00 21.43 ? 1023 LEU A CD1 1 ATOM 8124 C CD2 . LEU A 1 1023 ? 57.383 38.686 -11.683 1.00 22.59 ? 1023 LEU A CD2 1 ATOM 8125 N N . ASP A 1 1024 ? 61.163 36.099 -12.570 1.00 22.53 ? 1024 ASP A N 1 ATOM 8126 C CA . ASP A 1 1024 ? 62.138 35.425 -13.411 1.00 23.99 ? 1024 ASP A CA 1 ATOM 8127 C C . ASP A 1 1024 ? 62.709 36.358 -14.447 1.00 23.98 ? 1024 ASP A C 1 ATOM 8128 O O . ASP A 1 1024 ? 61.973 37.117 -15.123 1.00 23.98 ? 1024 ASP A O 1 ATOM 8129 C CB . ASP A 1 1024 ? 61.474 34.253 -14.145 1.00 28.99 ? 1024 ASP A CB 1 ATOM 8130 C CG . ASP A 1 1024 ? 61.150 33.091 -13.234 1.00 36.94 ? 1024 ASP A CG 1 ATOM 8131 O OD1 . ASP A 1 1024 ? 61.396 33.206 -11.999 1.00 42.54 ? 1024 ASP A OD1 1 ATOM 8132 O OD2 . ASP A 1 1024 ? 60.656 32.054 -13.766 1.00 40.78 ? 1024 ASP A OD2 1 ATOM 8133 N N . GLY A 1 1025 ? 64.019 36.258 -14.594 1.00 20.24 ? 1025 GLY A N 1 ATOM 8134 C CA . GLY A 1 1025 ? 64.751 37.032 -15.575 1.00 22.54 ? 1025 GLY A CA 1 ATOM 8135 C C . GLY A 1 1025 ? 64.688 38.511 -15.324 1.00 20.06 ? 1025 GLY A C 1 ATOM 8136 O O . GLY A 1 1025 ? 65.079 39.259 -16.207 1.00 21.99 ? 1025 GLY A O 1 ATOM 8137 N N . MET A 1 1026 ? 64.241 38.918 -14.128 1.00 18.30 ? 1026 MET A N 1 ATOM 8138 C CA . MET A 1 1026 ? 64.112 40.333 -13.781 1.00 19.54 ? 1026 MET A CA 1 ATOM 8139 C C . MET A 1 1026 ? 63.195 41.026 -14.776 1.00 16.63 ? 1026 MET A C 1 ATOM 8140 O O . MET A 1 1026 ? 63.369 42.238 -15.019 1.00 18.83 ? 1026 MET A O 1 ATOM 8141 C CB . MET A 1 1026 ? 65.473 41.029 -13.748 1.00 21.63 ? 1026 MET A CB 1 ATOM 8142 C CG . MET A 1 1026 ? 66.428 40.371 -12.729 1.00 26.10 ? 1026 MET A CG 1 ATOM 8143 S SD . MET A 1 1026 ? 68.107 41.018 -12.791 1.00 34.42 ? 1026 MET A SD 1 ATOM 8144 C CE . MET A 1 1026 ? 68.640 40.431 -14.474 1.00 28.67 ? 1026 MET A CE 1 ATOM 8145 N N . VAL A 1 1027 ? 62.211 40.304 -15.280 1.00 16.91 ? 1027 VAL A N 1 ATOM 8146 C CA . VAL A 1 1027 ? 61.259 40.885 -16.234 1.00 17.54 ? 1027 VAL A CA 1 ATOM 8147 C C . VAL A 1 1027 ? 59.902 41.092 -15.584 1.00 18.13 ? 1027 VAL A C 1 ATOM 8148 O O . VAL A 1 1027 ? 59.342 40.218 -14.944 1.00 19.16 ? 1027 VAL A O 1 ATOM 8149 C CB . VAL A 1 1027 ? 61.103 40.008 -17.496 1.00 15.45 ? 1027 VAL A CB 1 ATOM 8150 C CG1 . VAL A 1 1027 ? 59.972 40.533 -18.399 1.00 18.89 ? 1027 VAL A CG1 1 ATOM 8151 C CG2 . VAL A 1 1027 ? 62.438 39.988 -18.277 1.00 19.31 ? 1027 VAL A CG2 1 ATOM 8152 N N . ALA A 1 1028 ? 59.361 42.297 -15.756 1.00 16.50 ? 1028 ALA A N 1 ATOM 8153 C CA . ALA A 1 1028 ? 58.037 42.642 -15.194 1.00 18.85 ? 1028 ALA A CA 1 ATOM 8154 C C . ALA A 1 1028 ? 57.063 42.446 -16.286 1.00 20.21 ? 1028 ALA A C 1 ATOM 8155 O O . ALA A 1 1028 ? 57.089 43.182 -17.291 1.00 22.34 ? 1028 ALA A O 1 ATOM 8156 C CB . ALA A 1 1028 ? 57.995 44.120 -14.769 1.00 17.08 ? 1028 ALA A CB 1 ATOM 8157 N N . PRO A 1 1029 ? 56.156 41.498 -16.120 1.00 17.89 ? 1029 PRO A N 1 ATOM 8158 C CA . PRO A 1 1029 ? 55.148 41.257 -17.176 1.00 18.93 ? 1029 PRO A CA 1 ATOM 8159 C C . PRO A 1 1029 ? 54.116 42.388 -17.275 1.00 19.57 ? 1029 PRO A C 1 ATOM 8160 O O . PRO A 1 1029 ? 53.838 43.063 -16.294 1.00 25.20 ? 1029 PRO A O 1 ATOM 8161 C CB . PRO A 1 1029 ? 54.444 39.991 -16.717 1.00 20.12 ? 1029 PRO A CB 1 ATOM 8162 C CG . PRO A 1 1029 ? 55.303 39.430 -15.584 1.00 23.66 ? 1029 PRO A CG 1 ATOM 8163 C CD . PRO A 1 1029 ? 56.039 40.574 -14.981 1.00 15.89 ? 1029 PRO A CD 1 ATOM 8164 N N . GLU A 1 1030 ? 53.558 42.586 -18.455 1.00 17.74 ? 1030 GLU A N 1 ATOM 8165 C CA . GLU A 1 1030 ? 52.499 43.572 -18.568 1.00 17.55 ? 1030 GLU A CA 1 ATOM 8166 C C . GLU A 1 1030 ? 51.242 42.970 -17.901 1.00 19.48 ? 1030 GLU A C 1 ATOM 8167 O O . GLU A 1 1030 ? 51.099 41.726 -17.686 1.00 24.96 ? 1030 GLU A O 1 ATOM 8168 C CB . GLU A 1 1030 ? 52.205 43.924 -20.038 1.00 19.15 ? 1030 GLU A CB 1 ATOM 8169 C CG . GLU A 1 1030 ? 53.398 44.547 -20.787 1.00 19.19 ? 1030 GLU A CG 1 ATOM 8170 C CD . GLU A 1 1030 ? 53.048 44.876 -22.222 1.00 19.55 ? 1030 GLU A CD 1 ATOM 8171 O OE1 . GLU A 1 1030 ? 52.045 44.317 -22.728 1.00 23.80 ? 1030 GLU A OE1 1 ATOM 8172 O OE2 . GLU A 1 1030 ? 53.804 45.679 -22.847 1.00 16.77 ? 1030 GLU A OE2 1 ATOM 8173 N N . VAL A 1 1031 ? 50.318 43.842 -17.596 1.00 17.72 ? 1031 VAL A N 1 ATOM 8174 C CA . VAL A 1 1031 ? 49.124 43.454 -16.902 1.00 14.18 ? 1031 VAL A CA 1 ATOM 8175 C C . VAL A 1 1031 ? 47.942 43.271 -17.838 1.00 13.94 ? 1031 VAL A C 1 ATOM 8176 O O . VAL A 1 1031 ? 47.989 43.665 -19.012 1.00 14.39 ? 1031 VAL A O 1 ATOM 8177 C CB . VAL A 1 1031 ? 48.801 44.502 -15.820 1.00 17.27 ? 1031 VAL A CB 1 ATOM 8178 C CG1 . VAL A 1 1031 ? 50.011 44.589 -14.860 1.00 20.05 ? 1031 VAL A CG1 1 ATOM 8179 C CG2 . VAL A 1 1031 ? 48.502 45.825 -16.411 1.00 17.12 ? 1031 VAL A CG2 1 ATOM 8180 N N . CYS A 1 1032 ? 46.911 42.602 -17.338 1.00 11.97 ? 1032 CYS A N 1 ATOM 8181 C CA . CYS A 1 1032 ? 45.677 42.352 -18.102 1.00 13.40 ? 1032 CYS A CA 1 ATOM 8182 C C . CYS A 1 1032 ? 44.744 43.569 -18.160 1.00 11.53 ? 1032 CYS A C 1 ATOM 8183 O O . CYS A 1 1032 ? 44.864 44.491 -17.364 1.00 9.99 ? 1032 CYS A O 1 ATOM 8184 C CB . CYS A 1 1032 ? 44.883 41.237 -17.432 1.00 11.53 ? 1032 CYS A CB 1 ATOM 8185 S SG . CYS A 1 1032 ? 45.714 39.613 -17.621 1.00 21.28 ? 1032 CYS A SG 1 ATOM 8186 N N . PRO A 1 1033 ? 43.809 43.600 -19.138 1.00 10.16 ? 1033 PRO A N 1 ATOM 8187 C CA . PRO A 1 1033 ? 42.857 44.727 -19.187 1.00 9.31 ? 1033 PRO A CA 1 ATOM 8188 C C . PRO A 1 1033 ? 42.128 44.855 -17.831 1.00 8.58 ? 1033 PRO A C 1 ATOM 8189 O O . PRO A 1 1033 ? 41.605 43.887 -17.251 1.00 9.86 ? 1033 PRO A O 1 ATOM 8190 C CB . PRO A 1 1033 ? 41.884 44.340 -20.346 1.00 10.12 ? 1033 PRO A CB 1 ATOM 8191 C CG . PRO A 1 1033 ? 42.736 43.431 -21.232 1.00 12.61 ? 1033 PRO A CG 1 ATOM 8192 C CD . PRO A 1 1033 ? 43.573 42.622 -20.226 1.00 11.93 ? 1033 PRO A CD 1 ATOM 8193 N N . MET A 1 1034 ? 42.004 46.114 -17.426 1.00 8.39 ? 1034 MET A N 1 ATOM 8194 C CA . MET A 1 1034 ? 41.404 46.580 -16.194 1.00 9.20 ? 1034 MET A CA 1 ATOM 8195 C C . MET A 1 1034 ? 42.197 46.214 -14.944 1.00 10.29 ? 1034 MET A C 1 ATOM 8196 O O . MET A 1 1034 ? 41.739 46.546 -13.838 1.00 14.55 ? 1034 MET A O 1 ATOM 8197 C CB . MET A 1 1034 ? 39.934 46.146 -16.047 1.00 8.35 ? 1034 MET A CB 1 ATOM 8198 C CG . MET A 1 1034 ? 39.099 46.686 -17.193 1.00 9.57 ? 1034 MET A CG 1 ATOM 8199 S SD . MET A 1 1034 ? 39.087 48.454 -17.424 1.00 11.21 ? 1034 MET A SD 1 ATOM 8200 C CE . MET A 1 1034 ? 38.172 48.985 -15.866 1.00 12.52 ? 1034 MET A CE 1 ATOM 8201 N N . GLU A 1 1035 ? 43.394 45.725 -15.109 1.00 7.92 ? 1035 GLU A N 1 ATOM 8202 C CA . GLU A 1 1035 ? 44.216 45.388 -13.962 1.00 9.30 ? 1035 GLU A CA 1 ATOM 8203 C C . GLU A 1 1035 ? 45.286 46.464 -13.768 1.00 8.78 ? 1035 GLU A C 1 ATOM 8204 O O . GLU A 1 1035 ? 45.660 47.205 -14.686 1.00 8.59 ? 1035 GLU A O 1 ATOM 8205 C CB . GLU A 1 1035 ? 44.803 44.000 -14.150 1.00 13.74 ? 1035 GLU A CB 1 ATOM 8206 C CG . GLU A 1 1035 ? 43.749 42.906 -13.904 1.00 22.06 ? 1035 GLU A CG 1 ATOM 8207 C CD . GLU A 1 1035 ? 43.385 42.763 -12.417 1.00 30.06 ? 1035 GLU A CD 1 ATOM 8208 O OE1 . GLU A 1 1035 ? 42.737 43.679 -11.844 1.00 30.97 ? 1035 GLU A OE1 1 ATOM 8209 O OE2 . GLU A 1 1035 ? 43.782 41.727 -11.831 1.00 38.59 ? 1035 GLU A OE2 1 ATOM 8210 N N . THR A 1 1036 ? 45.777 46.527 -12.522 1.00 8.72 ? 1036 THR A N 1 ATOM 8211 C CA . THR A 1 1036 ? 46.837 47.439 -12.117 1.00 9.10 ? 1036 THR A CA 1 ATOM 8212 C C . THR A 1 1036 ? 47.835 46.620 -11.297 1.00 9.33 ? 1036 THR A C 1 ATOM 8213 O O . THR A 1 1036 ? 47.412 45.854 -10.404 1.00 10.42 ? 1036 THR A O 1 ATOM 8214 C CB . THR A 1 1036 ? 46.267 48.576 -11.249 1.00 7.86 ? 1036 THR A CB 1 ATOM 8215 O OG1 . THR A 1 1036 ? 45.177 49.186 -11.936 1.00 9.54 ? 1036 THR A OG1 1 ATOM 8216 C CG2 . THR A 1 1036 ? 47.314 49.611 -10.877 1.00 9.38 ? 1036 THR A CG2 1 ATOM 8217 N N . ALA A 1 1037 ? 49.137 46.726 -11.587 1.00 8.51 ? 1037 ALA A N 1 ATOM 8218 C CA . ALA A 1 1037 ? 50.162 45.998 -10.838 1.00 8.84 ? 1037 ALA A CA 1 ATOM 8219 C C . ALA A 1 1037 ? 51.258 46.964 -10.488 1.00 7.99 ? 1037 ALA A C 1 ATOM 8220 O O . ALA A 1 1037 ? 51.374 48.046 -11.085 1.00 9.96 ? 1037 ALA A O 1 ATOM 8221 C CB . ALA A 1 1037 ? 50.741 44.864 -11.694 1.00 11.20 ? 1037 ALA A CB 1 ATOM 8222 N N . ALA A 1 1038 ? 52.051 46.620 -9.503 1.00 7.23 ? 1038 ALA A N 1 ATOM 8223 C CA . ALA A 1 1038 ? 53.183 47.431 -9.116 1.00 7.63 ? 1038 ALA A CA 1 ATOM 8224 C C . ALA A 1 1038 ? 54.429 46.562 -9.149 1.00 6.98 ? 1038 ALA A C 1 ATOM 8225 O O . ALA A 1 1038 ? 54.386 45.372 -8.798 1.00 8.16 ? 1038 ALA A O 1 ATOM 8226 C CB . ALA A 1 1038 ? 53.000 48.054 -7.748 1.00 8.39 ? 1038 ALA A CB 1 ATOM 8227 N N . TYR A 1 1039 ? 55.532 47.186 -9.546 1.00 8.06 ? 1039 TYR A N 1 ATOM 8228 C CA . TYR A 1 1039 ? 56.798 46.469 -9.641 1.00 8.45 ? 1039 TYR A CA 1 ATOM 8229 C C . TYR A 1 1039 ? 57.875 47.340 -9.076 1.00 9.64 ? 1039 TYR A C 1 ATOM 8230 O O . TYR A 1 1039 ? 57.825 48.574 -9.216 1.00 9.85 ? 1039 TYR A O 1 ATOM 8231 C CB . TYR A 1 1039 ? 57.155 46.158 -11.102 1.00 9.42 ? 1039 TYR A CB 1 ATOM 8232 C CG . TYR A 1 1039 ? 56.200 45.272 -11.781 1.00 9.38 ? 1039 TYR A CG 1 ATOM 8233 C CD1 . TYR A 1 1039 ? 56.165 43.892 -11.538 1.00 10.28 ? 1039 TYR A CD1 1 ATOM 8234 C CD2 . TYR A 1 1039 ? 55.272 45.798 -12.696 1.00 12.18 ? 1039 TYR A CD2 1 ATOM 8235 C CE1 . TYR A 1 1039 ? 55.263 43.066 -12.188 1.00 13.19 ? 1039 TYR A CE1 1 ATOM 8236 C CE2 . TYR A 1 1039 ? 54.363 44.949 -13.373 1.00 14.57 ? 1039 TYR A CE2 1 ATOM 8237 C CZ . TYR A 1 1039 ? 54.379 43.598 -13.099 1.00 14.07 ? 1039 TYR A CZ 1 ATOM 8238 O OH . TYR A 1 1039 ? 53.498 42.799 -13.828 1.00 17.17 ? 1039 TYR A OH 1 ATOM 8239 N N . VAL A 1 1040 ? 58.881 46.735 -8.442 1.00 10.28 ? 1040 VAL A N 1 ATOM 8240 C CA . VAL A 1 1040 ? 60.039 47.487 -7.946 1.00 9.20 ? 1040 VAL A CA 1 ATOM 8241 C C . VAL A 1 1040 ? 61.282 46.830 -8.561 1.00 10.31 ? 1040 VAL A C 1 ATOM 8242 O O . VAL A 1 1040 ? 61.497 45.593 -8.417 1.00 11.89 ? 1040 VAL A O 1 ATOM 8243 C CB . VAL A 1 1040 ? 60.127 47.465 -6.408 1.00 9.73 ? 1040 VAL A CB 1 ATOM 8244 C CG1 . VAL A 1 1040 ? 61.496 48.137 -5.964 1.00 10.89 ? 1040 VAL A CG1 1 ATOM 8245 C CG2 . VAL A 1 1040 ? 58.956 48.248 -5.824 1.00 11.14 ? 1040 VAL A CG2 1 ATOM 8246 N N . SER A 1 1041 ? 62.097 47.617 -9.261 1.00 9.13 ? 1041 SER A N 1 ATOM 8247 C CA . SER A 1 1041 ? 63.367 47.136 -9.778 1.00 10.21 ? 1041 SER A CA 1 ATOM 8248 C C . SER A 1 1041 ? 64.482 47.621 -8.837 1.00 9.99 ? 1041 SER A C 1 ATOM 8249 O O . SER A 1 1041 ? 64.435 48.730 -8.277 1.00 10.40 ? 1041 SER A O 1 ATOM 8250 C CB . SER A 1 1041 ? 63.556 47.640 -11.216 1.00 11.65 ? 1041 SER A CB 1 ATOM 8251 O OG . SER A 1 1041 ? 63.656 49.058 -11.291 1.00 12.39 ? 1041 SER A OG 1 ATOM 8252 N N . SER A 1 1042 ? 65.452 46.726 -8.596 1.00 10.78 ? 1042 SER A N 1 ATOM 8253 C CA . SER A 1 1042 ? 66.601 47.025 -7.718 1.00 11.84 ? 1042 SER A CA 1 ATOM 8254 C C . SER A 1 1042 ? 67.850 47.061 -8.633 1.00 10.65 ? 1042 SER A C 1 ATOM 8255 O O . SER A 1 1042 ? 67.968 46.280 -9.580 1.00 15.57 ? 1042 SER A O 1 ATOM 8256 C CB . SER A 1 1042 ? 66.758 45.926 -6.646 1.00 11.98 ? 1042 SER A CB 1 ATOM 8257 O OG . SER A 1 1042 ? 65.654 45.933 -5.757 1.00 14.53 ? 1042 SER A OG 1 ATOM 8258 N N . HIS A 1 1043 ? 68.735 47.998 -8.343 1.00 12.94 ? 1043 HIS A N 1 ATOM 8259 C CA . HIS A 1 1043 ? 69.851 48.306 -9.225 1.00 13.18 ? 1043 HIS A CA 1 ATOM 8260 C C . HIS A 1 1043 ? 71.103 48.430 -8.403 1.00 15.36 ? 1043 HIS A C 1 ATOM 8261 O O . HIS A 1 1043 ? 71.112 49.032 -7.355 1.00 14.51 ? 1043 HIS A O 1 ATOM 8262 C CB . HIS A 1 1043 ? 69.601 49.591 -9.997 1.00 14.51 ? 1043 HIS A CB 1 ATOM 8263 C CG . HIS A 1 1043 ? 68.320 49.565 -10.748 1.00 12.69 ? 1043 HIS A CG 1 ATOM 8264 N ND1 . HIS A 1 1043 ? 68.238 49.166 -12.058 1.00 14.52 ? 1043 HIS A ND1 1 ATOM 8265 C CD2 . HIS A 1 1043 ? 67.052 49.779 -10.334 1.00 12.51 ? 1043 HIS A CD2 1 ATOM 8266 C CE1 . HIS A 1 1043 ? 66.973 49.183 -12.436 1.00 14.01 ? 1043 HIS A CE1 1 ATOM 8267 N NE2 . HIS A 1 1043 ? 66.237 49.561 -11.409 1.00 13.27 ? 1043 HIS A NE2 1 ATOM 8268 N N . SER A 1 1044 ? 72.174 47.828 -8.906 1.00 19.83 ? 1044 SER A N 1 ATOM 8269 C CA . SER A 1 1044 ? 73.382 47.863 -8.118 1.00 28.34 ? 1044 SER A CA 1 ATOM 8270 C C . SER A 1 1044 ? 74.298 48.993 -8.474 1.00 32.01 ? 1044 SER A C 1 ATOM 8271 O O . SER A 1 1044 ? 73.857 49.937 -9.171 1.00 29.35 ? 1044 SER A O 1 ATOM 8272 C CB . SER A 1 1044 ? 74.121 46.519 -8.226 1.00 31.30 ? 1044 SER A CB 1 ATOM 8273 O OG . SER A 1 1044 ? 73.777 45.848 -9.437 1.00 37.72 ? 1044 SER A OG 1 HETATM 8274 C C1 . NAG B 2 . ? 58.303 44.815 12.796 1.00 31.48 ? 1046 NAG A C1 1 HETATM 8275 C C2 . NAG B 2 . ? 59.383 44.452 13.811 1.00 36.31 ? 1046 NAG A C2 1 HETATM 8276 C C3 . NAG B 2 . ? 59.885 43.041 13.585 1.00 38.95 ? 1046 NAG A C3 1 HETATM 8277 C C4 . NAG B 2 . ? 58.720 42.070 13.626 1.00 40.01 ? 1046 NAG A C4 1 HETATM 8278 C C5 . NAG B 2 . ? 57.663 42.506 12.609 1.00 40.87 ? 1046 NAG A C5 1 HETATM 8279 C C6 . NAG B 2 . ? 56.422 41.635 12.642 1.00 42.62 ? 1046 NAG A C6 1 HETATM 8280 C C7 . NAG B 2 . ? 60.595 46.354 14.621 1.00 43.06 ? 1046 NAG A C7 1 HETATM 8281 C C8 . NAG B 2 . ? 60.217 46.016 16.068 1.00 44.11 ? 1046 NAG A C8 1 HETATM 8282 N N2 . NAG B 2 . ? 60.494 45.377 13.721 1.00 40.76 ? 1046 NAG A N2 1 HETATM 8283 O O3 . NAG B 2 . ? 60.818 42.729 14.608 1.00 41.37 ? 1046 NAG A O3 1 HETATM 8284 O O4 . NAG B 2 . ? 59.193 40.767 13.304 1.00 43.80 ? 1046 NAG A O4 1 HETATM 8285 O O5 . NAG B 2 . ? 57.235 43.871 12.878 1.00 36.62 ? 1046 NAG A O5 1 HETATM 8286 O O6 . NAG B 2 . ? 55.329 42.271 11.983 1.00 46.78 ? 1046 NAG A O6 1 HETATM 8287 O O7 . NAG B 2 . ? 60.959 47.497 14.327 1.00 47.12 ? 1046 NAG A O7 1 HETATM 8288 ZN ZN . ZN C 3 . ? 34.483 64.248 8.119 1.00 7.04 ? 1047 ZN A ZN 1 HETATM 8289 C C1 . SWA D 4 . ? 31.037 66.706 6.172 1.00 6.81 ? 1048 SWA A C1 1 HETATM 8290 O O1 . SWA D 4 . ? 31.473 67.889 5.510 1.00 8.05 ? 1048 SWA A O1 1 HETATM 8291 C C3 . SWA D 4 . ? 31.334 66.853 7.643 1.00 8.00 ? 1048 SWA A C3 1 HETATM 8292 N N4 . SWA D 4 . ? 30.826 65.639 8.314 1.00 7.06 ? 1048 SWA A N4 1 HETATM 8293 C C5 . SWA D 4 . ? 29.363 65.524 8.189 1.00 7.90 ? 1048 SWA A C5 1 HETATM 8294 C C6 . SWA D 4 . ? 29.088 65.370 6.709 1.00 9.72 ? 1048 SWA A C6 1 HETATM 8295 C C2 . SWA D 4 . ? 29.545 66.567 5.899 1.00 8.54 ? 1048 SWA A C2 1 HETATM 8296 C C9 . SWA D 4 . ? 31.292 65.888 9.690 1.00 9.30 ? 1048 SWA A C9 1 HETATM 8297 C C8 . SWA D 4 . ? 32.701 66.416 9.475 1.00 8.20 ? 1048 SWA A C8 1 HETATM 8298 O O13 . SWA D 4 . ? 33.610 65.328 9.736 1.00 7.96 ? 1048 SWA A O13 1 HETATM 8299 C C7 . SWA D 4 . ? 32.798 66.955 8.052 1.00 6.49 ? 1048 SWA A C7 1 HETATM 8300 O O11 . SWA D 4 . ? 33.664 66.112 7.279 1.00 7.29 ? 1048 SWA A O11 1 HETATM 8301 C C1 . MRD E 5 . ? 14.642 61.209 10.243 1.00 11.40 ? 1049 MRD A C1 1 HETATM 8302 C C2 . MRD E 5 . ? 16.085 61.206 10.540 1.00 13.55 ? 1049 MRD A C2 1 HETATM 8303 O O2 . MRD E 5 . ? 16.733 60.184 9.678 1.00 20.29 ? 1049 MRD A O2 1 HETATM 8304 C CM . MRD E 5 . ? 16.660 62.598 10.174 1.00 18.78 ? 1049 MRD A CM 1 HETATM 8305 C C3 . MRD E 5 . ? 16.224 60.882 12.052 1.00 14.53 ? 1049 MRD A C3 1 HETATM 8306 C C4 . MRD E 5 . ? 17.598 60.719 12.626 1.00 12.81 ? 1049 MRD A C4 1 HETATM 8307 O O4 . MRD E 5 . ? 17.488 59.795 13.740 1.00 11.97 ? 1049 MRD A O4 1 HETATM 8308 C C5 . MRD E 5 . ? 18.124 62.063 13.174 1.00 14.68 ? 1049 MRD A C5 1 HETATM 8309 O O . HOH F 6 . ? 27.863 46.955 -31.410 1.00 25.12 ? 1050 HOH A O 1 HETATM 8310 O O . HOH F 6 . ? 28.213 44.394 -29.544 1.00 25.32 ? 1051 HOH A O 1 HETATM 8311 O O . HOH F 6 . ? 26.116 44.270 -27.219 1.00 27.96 ? 1052 HOH A O 1 HETATM 8312 O O . HOH F 6 . ? 26.777 41.618 -27.546 1.00 31.68 ? 1053 HOH A O 1 HETATM 8313 O O . HOH F 6 . ? 27.618 39.652 -24.673 1.00 40.84 ? 1054 HOH A O 1 HETATM 8314 O O . HOH F 6 . ? 27.384 38.599 -22.259 1.00 28.99 ? 1055 HOH A O 1 HETATM 8315 O O . HOH F 6 . ? 28.426 41.312 -21.674 1.00 11.83 ? 1056 HOH A O 1 HETATM 8316 O O . HOH F 6 . ? 27.431 36.575 -19.744 1.00 25.62 ? 1057 HOH A O 1 HETATM 8317 O O . HOH F 6 . ? 29.378 35.080 -16.441 1.00 32.93 ? 1058 HOH A O 1 HETATM 8318 O O . HOH F 6 . ? 30.155 35.153 -12.396 1.00 21.67 ? 1059 HOH A O 1 HETATM 8319 O O . HOH F 6 . ? 30.492 34.678 -9.682 1.00 31.13 ? 1060 HOH A O 1 HETATM 8320 O O . HOH F 6 . ? 28.077 35.322 -6.782 1.00 19.22 ? 1061 HOH A O 1 HETATM 8321 O O . HOH F 6 . ? 25.255 34.336 -6.807 1.00 42.28 ? 1062 HOH A O 1 HETATM 8322 O O . HOH F 6 . ? 26.943 33.854 -3.255 1.00 29.44 ? 1063 HOH A O 1 HETATM 8323 O O . HOH F 6 . ? 29.872 34.086 -1.506 1.00 24.69 ? 1064 HOH A O 1 HETATM 8324 O O . HOH F 6 . ? 31.912 34.365 -3.217 1.00 21.09 ? 1065 HOH A O 1 HETATM 8325 O O . HOH F 6 . ? 33.122 36.670 -4.358 1.00 14.80 ? 1066 HOH A O 1 HETATM 8326 O O . HOH F 6 . ? 32.169 39.176 -4.883 1.00 10.11 ? 1067 HOH A O 1 HETATM 8327 O O . HOH F 6 . ? 35.826 35.993 -4.469 1.00 19.41 ? 1068 HOH A O 1 HETATM 8328 O O . HOH F 6 . ? 39.751 38.772 -3.445 1.00 21.37 ? 1069 HOH A O 1 HETATM 8329 O O . HOH F 6 . ? 39.820 39.735 -0.287 1.00 25.09 ? 1070 HOH A O 1 HETATM 8330 O O . HOH F 6 . ? 41.835 40.370 0.682 1.00 39.20 ? 1071 HOH A O 1 HETATM 8331 O O . HOH F 6 . ? 42.478 39.428 -1.449 1.00 29.07 ? 1072 HOH A O 1 HETATM 8332 O O . HOH F 6 . ? 44.388 41.822 -0.466 1.00 15.89 ? 1073 HOH A O 1 HETATM 8333 O O . HOH F 6 . ? 45.919 39.759 0.076 1.00 32.38 ? 1074 HOH A O 1 HETATM 8334 O O . HOH F 6 . ? 48.266 40.813 -0.972 1.00 21.50 ? 1075 HOH A O 1 HETATM 8335 O O . HOH F 6 . ? 49.489 40.889 1.443 1.00 26.47 ? 1076 HOH A O 1 HETATM 8336 O O . HOH F 6 . ? 48.009 41.775 3.764 1.00 15.78 ? 1077 HOH A O 1 HETATM 8337 O O . HOH F 6 . ? 47.577 40.101 5.878 1.00 38.49 ? 1078 HOH A O 1 HETATM 8338 O O . HOH F 6 . ? 48.977 41.721 8.293 1.00 29.05 ? 1079 HOH A O 1 HETATM 8339 O O . HOH F 6 . ? 49.917 44.093 7.162 1.00 16.64 ? 1080 HOH A O 1 HETATM 8340 O O . HOH F 6 . ? 49.272 44.150 4.474 1.00 13.48 ? 1081 HOH A O 1 HETATM 8341 O O . HOH F 6 . ? 51.543 44.434 3.118 1.00 19.80 ? 1082 HOH A O 1 HETATM 8342 O O . HOH F 6 . ? 51.777 46.537 1.353 1.00 10.36 ? 1083 HOH A O 1 HETATM 8343 O O . HOH F 6 . ? 49.787 48.431 1.419 1.00 9.06 ? 1084 HOH A O 1 HETATM 8344 O O . HOH F 6 . ? 47.373 45.979 3.748 1.00 10.11 ? 1085 HOH A O 1 HETATM 8345 O O . HOH F 6 . ? 53.790 45.842 4.779 1.00 35.33 ? 1086 HOH A O 1 HETATM 8346 O O . HOH F 6 . ? 52.741 43.710 7.659 1.00 38.29 ? 1087 HOH A O 1 HETATM 8347 O O . HOH F 6 . ? 51.315 45.067 9.911 1.00 28.91 ? 1088 HOH A O 1 HETATM 8348 O O . HOH F 6 . ? 47.066 45.930 11.311 1.00 33.28 ? 1089 HOH A O 1 HETATM 8349 O O . HOH F 6 . ? 46.976 48.528 11.587 1.00 16.49 ? 1090 HOH A O 1 HETATM 8350 O O . HOH F 6 . ? 47.844 49.498 13.869 1.00 12.47 ? 1091 HOH A O 1 HETATM 8351 O O . HOH F 6 . ? 48.001 48.305 16.499 1.00 15.80 ? 1092 HOH A O 1 HETATM 8352 O O . HOH F 6 . ? 46.001 46.045 16.456 1.00 27.84 ? 1093 HOH A O 1 HETATM 8353 O O . HOH F 6 . ? 43.890 44.904 19.355 1.00 38.87 ? 1094 HOH A O 1 HETATM 8354 O O . HOH F 6 . ? 45.758 45.132 23.348 1.00 29.70 ? 1095 HOH A O 1 HETATM 8355 O O . HOH F 6 . ? 46.907 45.757 26.478 1.00 30.17 ? 1096 HOH A O 1 HETATM 8356 O O . HOH F 6 . ? 49.515 46.121 26.740 1.00 32.55 ? 1097 HOH A O 1 HETATM 8357 O O . HOH F 6 . ? 50.926 43.933 26.620 1.00 35.90 ? 1098 HOH A O 1 HETATM 8358 O O . HOH F 6 . ? 49.958 47.457 29.095 1.00 18.57 ? 1099 HOH A O 1 HETATM 8359 O O . HOH F 6 . ? 49.509 45.736 31.172 1.00 23.40 ? 1100 HOH A O 1 HETATM 8360 O O . HOH F 6 . ? 47.762 43.857 30.388 1.00 34.18 ? 1101 HOH A O 1 HETATM 8361 O O . HOH F 6 . ? 49.237 50.042 28.346 1.00 13.26 ? 1102 HOH A O 1 HETATM 8362 O O . HOH F 6 . ? 51.951 50.480 27.430 1.00 24.44 ? 1103 HOH A O 1 HETATM 8363 O O . HOH F 6 . ? 52.324 48.863 25.687 1.00 27.71 ? 1104 HOH A O 1 HETATM 8364 O O . HOH F 6 . ? 53.327 52.601 26.334 1.00 18.48 ? 1105 HOH A O 1 HETATM 8365 O O . HOH F 6 . ? 55.768 52.021 27.490 1.00 25.02 ? 1106 HOH A O 1 HETATM 8366 O O . HOH F 6 . ? 56.111 53.407 29.869 1.00 33.73 ? 1107 HOH A O 1 HETATM 8367 O O . HOH F 6 . ? 57.774 55.457 29.412 1.00 33.49 ? 1108 HOH A O 1 HETATM 8368 O O . HOH F 6 . ? 58.878 56.714 31.337 1.00 33.43 ? 1109 HOH A O 1 HETATM 8369 O O . HOH F 6 . ? 59.076 55.374 27.130 1.00 23.59 ? 1110 HOH A O 1 HETATM 8370 O O . HOH F 6 . ? 58.023 52.824 26.217 1.00 26.16 ? 1111 HOH A O 1 HETATM 8371 O O . HOH F 6 . ? 59.484 50.947 24.800 1.00 25.29 ? 1112 HOH A O 1 HETATM 8372 O O . HOH F 6 . ? 58.559 51.096 22.235 1.00 19.77 ? 1113 HOH A O 1 HETATM 8373 O O . HOH F 6 . ? 60.336 50.954 20.385 1.00 32.69 ? 1114 HOH A O 1 HETATM 8374 O O . HOH F 6 . ? 58.748 48.735 19.155 1.00 27.61 ? 1115 HOH A O 1 HETATM 8375 O O . HOH F 6 . ? 57.229 48.871 21.359 1.00 18.96 ? 1116 HOH A O 1 HETATM 8376 O O . HOH F 6 . ? 56.675 47.149 23.368 1.00 37.30 ? 1117 HOH A O 1 HETATM 8377 O O . HOH F 6 . ? 57.454 49.325 16.642 1.00 28.02 ? 1118 HOH A O 1 HETATM 8378 O O . HOH F 6 . ? 55.129 50.400 16.859 1.00 22.97 ? 1119 HOH A O 1 HETATM 8379 O O . HOH F 6 . ? 54.181 47.606 15.560 1.00 21.65 ? 1120 HOH A O 1 HETATM 8380 O O . HOH F 6 . ? 56.748 46.575 15.765 1.00 26.43 ? 1121 HOH A O 1 HETATM 8381 O O . HOH F 6 . ? 58.786 50.966 14.838 1.00 32.71 ? 1122 HOH A O 1 HETATM 8382 O O . HOH F 6 . ? 60.363 54.253 14.762 1.00 27.58 ? 1123 HOH A O 1 HETATM 8383 O O . HOH F 6 . ? 60.652 56.727 15.907 1.00 26.83 ? 1124 HOH A O 1 HETATM 8384 O O . HOH F 6 . ? 61.607 58.877 14.890 1.00 24.25 ? 1125 HOH A O 1 HETATM 8385 O O . HOH F 6 . ? 60.838 61.211 13.626 1.00 32.91 ? 1126 HOH A O 1 HETATM 8386 O O . HOH F 6 . ? 61.021 63.530 15.146 1.00 22.59 ? 1127 HOH A O 1 HETATM 8387 O O . HOH F 6 . ? 63.512 59.596 16.897 1.00 31.51 ? 1128 HOH A O 1 HETATM 8388 O O . HOH F 6 . ? 65.372 55.840 21.297 1.00 36.57 ? 1129 HOH A O 1 HETATM 8389 O O . HOH F 6 . ? 63.330 57.705 25.790 1.00 40.55 ? 1130 HOH A O 1 HETATM 8390 O O . HOH F 6 . ? 62.189 62.528 25.715 1.00 15.58 ? 1131 HOH A O 1 HETATM 8391 O O . HOH F 6 . ? 59.140 62.303 25.766 1.00 20.92 ? 1132 HOH A O 1 HETATM 8392 O O . HOH F 6 . ? 56.858 64.913 24.323 1.00 21.95 ? 1133 HOH A O 1 HETATM 8393 O O . HOH F 6 . ? 57.181 67.406 22.710 1.00 31.51 ? 1134 HOH A O 1 HETATM 8394 O O . HOH F 6 . ? 52.910 69.684 18.346 1.00 22.39 ? 1135 HOH A O 1 HETATM 8395 O O . HOH F 6 . ? 52.534 72.479 18.315 1.00 22.44 ? 1136 HOH A O 1 HETATM 8396 O O . HOH F 6 . ? 50.885 76.402 14.461 1.00 19.73 ? 1137 HOH A O 1 HETATM 8397 O O . HOH F 6 . ? 47.315 78.512 11.627 1.00 33.25 ? 1138 HOH A O 1 HETATM 8398 O O . HOH F 6 . ? 46.074 77.763 9.491 1.00 20.06 ? 1139 HOH A O 1 HETATM 8399 O O . HOH F 6 . ? 48.172 76.723 8.241 1.00 33.25 ? 1140 HOH A O 1 HETATM 8400 O O . HOH F 6 . ? 46.685 74.556 7.779 1.00 10.62 ? 1141 HOH A O 1 HETATM 8401 O O . HOH F 6 . ? 49.176 76.522 5.496 1.00 31.59 ? 1142 HOH A O 1 HETATM 8402 O O . HOH F 6 . ? 45.928 79.761 4.894 1.00 27.67 ? 1143 HOH A O 1 HETATM 8403 O O . HOH F 6 . ? 43.351 80.725 5.215 1.00 23.40 ? 1144 HOH A O 1 HETATM 8404 O O . HOH F 6 . ? 35.903 81.143 6.424 1.00 16.99 ? 1145 HOH A O 1 HETATM 8405 O O . HOH F 6 . ? 31.813 80.327 7.233 1.00 36.48 ? 1146 HOH A O 1 HETATM 8406 O O . HOH F 6 . ? 27.866 82.106 6.734 1.00 32.37 ? 1147 HOH A O 1 HETATM 8407 O O . HOH F 6 . ? 27.480 82.414 3.329 1.00 27.75 ? 1148 HOH A O 1 HETATM 8408 O O . HOH F 6 . ? 29.749 83.063 2.488 1.00 19.93 ? 1149 HOH A O 1 HETATM 8409 O O . HOH F 6 . ? 31.574 83.609 4.325 1.00 29.86 ? 1150 HOH A O 1 HETATM 8410 O O . HOH F 6 . ? 32.697 84.267 0.292 1.00 27.05 ? 1151 HOH A O 1 HETATM 8411 O O . HOH F 6 . ? 31.250 81.797 0.503 1.00 16.31 ? 1152 HOH A O 1 HETATM 8412 O O . HOH F 6 . ? 37.543 80.553 -0.587 1.00 22.86 ? 1153 HOH A O 1 HETATM 8413 O O . HOH F 6 . ? 37.939 83.243 -1.035 1.00 29.35 ? 1154 HOH A O 1 HETATM 8414 O O . HOH F 6 . ? 37.341 83.525 -4.082 1.00 28.73 ? 1155 HOH A O 1 HETATM 8415 O O . HOH F 6 . ? 38.678 80.408 -3.190 1.00 29.45 ? 1156 HOH A O 1 HETATM 8416 O O . HOH F 6 . ? 41.005 81.830 -3.663 1.00 33.73 ? 1157 HOH A O 1 HETATM 8417 O O . HOH F 6 . ? 41.130 84.096 -2.254 1.00 40.16 ? 1158 HOH A O 1 HETATM 8418 O O . HOH F 6 . ? 36.228 79.222 -5.064 1.00 19.30 ? 1159 HOH A O 1 HETATM 8419 O O . HOH F 6 . ? 35.705 77.631 -7.366 1.00 12.03 ? 1160 HOH A O 1 HETATM 8420 O O . HOH F 6 . ? 34.491 79.214 -9.196 1.00 9.84 ? 1161 HOH A O 1 HETATM 8421 O O . HOH F 6 . ? 32.705 81.108 -11.753 1.00 9.84 ? 1162 HOH A O 1 HETATM 8422 O O . HOH F 6 . ? 33.503 83.616 -10.476 1.00 14.09 ? 1163 HOH A O 1 HETATM 8423 O O . HOH F 6 . ? 31.998 85.279 -8.593 1.00 20.63 ? 1164 HOH A O 1 HETATM 8424 O O . HOH F 6 . ? 32.788 85.448 -5.633 1.00 16.93 ? 1165 HOH A O 1 HETATM 8425 O O . HOH F 6 . ? 35.464 86.150 -8.146 1.00 34.68 ? 1166 HOH A O 1 HETATM 8426 O O . HOH F 6 . ? 34.116 87.185 -10.545 1.00 32.99 ? 1167 HOH A O 1 HETATM 8427 O O . HOH F 6 . ? 30.165 87.200 -15.071 1.00 22.90 ? 1168 HOH A O 1 HETATM 8428 O O . HOH F 6 . ? 27.656 86.412 -14.633 1.00 26.68 ? 1169 HOH A O 1 HETATM 8429 O O . HOH F 6 . ? 27.446 88.699 -12.508 1.00 27.76 ? 1170 HOH A O 1 HETATM 8430 O O . HOH F 6 . ? 29.397 87.450 -17.803 1.00 28.47 ? 1171 HOH A O 1 HETATM 8431 O O . HOH F 6 . ? 31.609 85.925 -19.967 1.00 18.80 ? 1172 HOH A O 1 HETATM 8432 O O . HOH F 6 . ? 33.358 84.404 -18.319 1.00 15.80 ? 1173 HOH A O 1 HETATM 8433 O O . HOH F 6 . ? 35.357 86.341 -18.040 1.00 28.16 ? 1174 HOH A O 1 HETATM 8434 O O . HOH F 6 . ? 34.984 87.882 -19.786 1.00 32.29 ? 1175 HOH A O 1 HETATM 8435 O O . HOH F 6 . ? 38.191 86.854 -17.321 1.00 30.23 ? 1176 HOH A O 1 HETATM 8436 O O . HOH F 6 . ? 40.204 85.918 -22.101 1.00 25.15 ? 1177 HOH A O 1 HETATM 8437 O O . HOH F 6 . ? 39.615 81.702 -22.206 1.00 32.33 ? 1178 HOH A O 1 HETATM 8438 O O . HOH F 6 . ? 41.842 79.371 -23.450 1.00 22.97 ? 1179 HOH A O 1 HETATM 8439 O O . HOH F 6 . ? 44.032 79.220 -21.506 1.00 32.09 ? 1180 HOH A O 1 HETATM 8440 O O . HOH F 6 . ? 46.689 80.363 -22.506 1.00 27.25 ? 1181 HOH A O 1 HETATM 8441 O O . HOH F 6 . ? 45.848 82.812 -25.470 1.00 32.36 ? 1182 HOH A O 1 HETATM 8442 O O . HOH F 6 . ? 43.455 81.057 -25.424 1.00 34.57 ? 1183 HOH A O 1 HETATM 8443 O O . HOH F 6 . ? 44.307 83.757 -27.869 1.00 23.48 ? 1184 HOH A O 1 HETATM 8444 O O . HOH F 6 . ? 44.821 82.628 -30.593 1.00 18.83 ? 1185 HOH A O 1 HETATM 8445 O O . HOH F 6 . ? 41.479 82.770 -28.951 1.00 29.17 ? 1186 HOH A O 1 HETATM 8446 O O . HOH F 6 . ? 40.517 82.946 -31.357 1.00 24.85 ? 1187 HOH A O 1 HETATM 8447 O O . HOH F 6 . ? 38.113 81.749 -31.454 1.00 11.03 ? 1188 HOH A O 1 HETATM 8448 O O . HOH F 6 . ? 39.071 83.128 -27.388 1.00 21.77 ? 1189 HOH A O 1 HETATM 8449 O O . HOH F 6 . ? 42.435 79.985 -31.751 1.00 29.02 ? 1190 HOH A O 1 HETATM 8450 O O . HOH F 6 . ? 42.781 78.424 -29.903 1.00 30.45 ? 1191 HOH A O 1 HETATM 8451 O O . HOH F 6 . ? 44.624 79.300 -33.378 1.00 18.75 ? 1192 HOH A O 1 HETATM 8452 O O . HOH F 6 . ? 47.979 74.490 -28.944 1.00 32.89 ? 1193 HOH A O 1 HETATM 8453 O O . HOH F 6 . ? 47.022 75.023 -26.397 1.00 34.40 ? 1194 HOH A O 1 HETATM 8454 O O . HOH F 6 . ? 47.248 73.107 -24.778 1.00 35.16 ? 1195 HOH A O 1 HETATM 8455 O O . HOH F 6 . ? 48.581 72.213 -26.300 1.00 25.93 ? 1196 HOH A O 1 HETATM 8456 O O . HOH F 6 . ? 50.288 73.519 -25.320 1.00 23.72 ? 1197 HOH A O 1 HETATM 8457 O O . HOH F 6 . ? 50.835 70.811 -23.630 1.00 16.69 ? 1198 HOH A O 1 HETATM 8458 O O . HOH F 6 . ? 49.669 73.399 -21.833 1.00 22.49 ? 1199 HOH A O 1 HETATM 8459 O O . HOH F 6 . ? 51.217 71.403 -20.244 1.00 17.08 ? 1200 HOH A O 1 HETATM 8460 O O . HOH F 6 . ? 53.563 72.601 -19.237 1.00 13.44 ? 1201 HOH A O 1 HETATM 8461 O O . HOH F 6 . ? 49.920 70.786 -17.624 1.00 25.88 ? 1202 HOH A O 1 HETATM 8462 O O . HOH F 6 . ? 47.462 69.927 -16.788 1.00 29.87 ? 1203 HOH A O 1 HETATM 8463 O O . HOH F 6 . ? 45.529 69.810 -18.564 1.00 24.09 ? 1204 HOH A O 1 HETATM 8464 O O . HOH F 6 . ? 46.936 72.502 -17.632 1.00 25.71 ? 1205 HOH A O 1 HETATM 8465 O O . HOH F 6 . ? 47.362 71.803 -20.269 1.00 20.46 ? 1206 HOH A O 1 HETATM 8466 O O . HOH F 6 . ? 46.833 68.138 -24.701 1.00 25.26 ? 1207 HOH A O 1 HETATM 8467 O O . HOH F 6 . ? 45.375 67.775 -27.724 1.00 17.97 ? 1208 HOH A O 1 HETATM 8468 O O . HOH F 6 . ? 45.865 65.454 -28.609 1.00 32.40 ? 1209 HOH A O 1 HETATM 8469 O O . HOH F 6 . ? 48.081 64.350 -28.550 1.00 20.67 ? 1210 HOH A O 1 HETATM 8470 O O . HOH F 6 . ? 48.034 64.816 -25.904 1.00 22.03 ? 1211 HOH A O 1 HETATM 8471 O O . HOH F 6 . ? 46.613 61.717 -25.991 1.00 17.10 ? 1212 HOH A O 1 HETATM 8472 O O . HOH F 6 . ? 47.760 59.250 -25.717 1.00 11.97 ? 1213 HOH A O 1 HETATM 8473 O O . HOH F 6 . ? 49.155 59.238 -28.663 1.00 16.31 ? 1214 HOH A O 1 HETATM 8474 O O . HOH F 6 . ? 49.865 58.370 -31.013 1.00 30.02 ? 1215 HOH A O 1 HETATM 8475 O O . HOH F 6 . ? 50.271 60.979 -31.153 1.00 15.75 ? 1216 HOH A O 1 HETATM 8476 O O . HOH F 6 . ? 49.551 61.908 -33.982 1.00 35.45 ? 1217 HOH A O 1 HETATM 8477 O O . HOH F 6 . ? 46.036 60.143 -30.964 1.00 48.11 ? 1218 HOH A O 1 HETATM 8478 O O . HOH F 6 . ? 47.319 61.326 -28.910 1.00 24.96 ? 1219 HOH A O 1 HETATM 8479 O O . HOH F 6 . ? 43.718 63.009 -28.709 1.00 8.82 ? 1220 HOH A O 1 HETATM 8480 O O . HOH F 6 . ? 41.547 61.241 -29.808 1.00 16.97 ? 1221 HOH A O 1 HETATM 8481 O O . HOH F 6 . ? 42.966 59.558 -31.512 1.00 21.79 ? 1222 HOH A O 1 HETATM 8482 O O . HOH F 6 . ? 42.766 56.771 -31.569 1.00 20.86 ? 1223 HOH A O 1 HETATM 8483 O O . HOH F 6 . ? 40.749 56.045 -33.354 1.00 24.18 ? 1224 HOH A O 1 HETATM 8484 O O . HOH F 6 . ? 38.526 55.184 -31.762 1.00 13.89 ? 1225 HOH A O 1 HETATM 8485 O O . HOH F 6 . ? 36.509 56.505 -32.864 1.00 31.87 ? 1226 HOH A O 1 HETATM 8486 O O . HOH F 6 . ? 36.958 58.961 -33.581 1.00 21.97 ? 1227 HOH A O 1 HETATM 8487 O O . HOH F 6 . ? 37.517 61.385 -32.543 1.00 22.30 ? 1228 HOH A O 1 HETATM 8488 O O . HOH F 6 . ? 40.147 62.471 -32.093 1.00 14.49 ? 1229 HOH A O 1 HETATM 8489 O O . HOH F 6 . ? 43.068 64.373 -31.543 1.00 29.91 ? 1230 HOH A O 1 HETATM 8490 O O . HOH F 6 . ? 42.948 68.450 -30.268 1.00 26.69 ? 1231 HOH A O 1 HETATM 8491 O O . HOH F 6 . ? 43.006 68.963 -28.015 1.00 35.84 ? 1232 HOH A O 1 HETATM 8492 O O . HOH F 6 . ? 43.333 68.246 -25.085 1.00 12.42 ? 1233 HOH A O 1 HETATM 8493 O O . HOH F 6 . ? 45.372 71.637 -25.964 1.00 33.01 ? 1234 HOH A O 1 HETATM 8494 O O . HOH F 6 . ? 47.036 68.466 -30.346 1.00 13.97 ? 1235 HOH A O 1 HETATM 8495 O O . HOH F 6 . ? 41.167 68.359 -32.657 1.00 12.95 ? 1236 HOH A O 1 HETATM 8496 O O . HOH F 6 . ? 39.307 69.116 -35.480 1.00 12.61 ? 1237 HOH A O 1 HETATM 8497 O O . HOH F 6 . ? 38.556 69.189 -38.252 1.00 14.48 ? 1238 HOH A O 1 HETATM 8498 O O . HOH F 6 . ? 34.243 66.273 -42.603 1.00 32.55 ? 1239 HOH A O 1 HETATM 8499 O O . HOH F 6 . ? 33.876 70.006 -45.120 1.00 34.15 ? 1240 HOH A O 1 HETATM 8500 O O . HOH F 6 . ? 31.071 69.171 -45.576 1.00 36.08 ? 1241 HOH A O 1 HETATM 8501 O O . HOH F 6 . ? 27.921 68.779 -46.682 1.00 34.20 ? 1242 HOH A O 1 HETATM 8502 O O . HOH F 6 . ? 23.140 65.892 -43.522 1.00 32.19 ? 1243 HOH A O 1 HETATM 8503 O O . HOH F 6 . ? 20.773 61.025 -40.421 1.00 32.42 ? 1244 HOH A O 1 HETATM 8504 O O . HOH F 6 . ? 18.997 60.481 -38.200 1.00 19.39 ? 1245 HOH A O 1 HETATM 8505 O O . HOH F 6 . ? 19.898 58.207 -36.997 1.00 32.15 ? 1246 HOH A O 1 HETATM 8506 O O . HOH F 6 . ? 20.706 58.876 -34.699 1.00 19.18 ? 1247 HOH A O 1 HETATM 8507 O O . HOH F 6 . ? 18.901 57.908 -32.973 1.00 21.72 ? 1248 HOH A O 1 HETATM 8508 O O . HOH F 6 . ? 19.319 54.883 -33.471 1.00 41.19 ? 1249 HOH A O 1 HETATM 8509 O O . HOH F 6 . ? 20.898 55.103 -35.783 1.00 28.26 ? 1250 HOH A O 1 HETATM 8510 O O . HOH F 6 . ? 22.423 56.802 -34.273 1.00 17.62 ? 1251 HOH A O 1 HETATM 8511 O O . HOH F 6 . ? 21.603 61.450 -34.943 1.00 20.46 ? 1252 HOH A O 1 HETATM 8512 O O . HOH F 6 . ? 22.230 63.449 -33.047 1.00 14.72 ? 1253 HOH A O 1 HETATM 8513 O O . HOH F 6 . ? 18.290 65.065 -26.914 1.00 20.87 ? 1254 HOH A O 1 HETATM 8514 O O . HOH F 6 . ? 17.098 67.376 -25.983 1.00 32.59 ? 1255 HOH A O 1 HETATM 8515 O O . HOH F 6 . ? 17.227 70.212 -23.459 1.00 15.87 ? 1256 HOH A O 1 HETATM 8516 O O . HOH F 6 . ? 14.525 70.477 -23.095 1.00 20.91 ? 1257 HOH A O 1 HETATM 8517 O O . HOH F 6 . ? 15.078 73.817 -22.114 1.00 34.34 ? 1258 HOH A O 1 HETATM 8518 O O . HOH F 6 . ? 15.950 75.208 -24.019 1.00 35.07 ? 1259 HOH A O 1 HETATM 8519 O O . HOH F 6 . ? 16.552 74.634 -28.729 1.00 45.56 ? 1260 HOH A O 1 HETATM 8520 O O . HOH F 6 . ? 18.735 70.514 -30.264 1.00 32.44 ? 1261 HOH A O 1 HETATM 8521 O O . HOH F 6 . ? 20.813 68.864 -31.689 1.00 38.24 ? 1262 HOH A O 1 HETATM 8522 O O . HOH F 6 . ? 22.766 78.680 -30.440 1.00 17.04 ? 1263 HOH A O 1 HETATM 8523 O O . HOH F 6 . ? 22.752 77.385 -27.421 1.00 26.24 ? 1264 HOH A O 1 HETATM 8524 O O . HOH F 6 . ? 23.252 78.503 -24.889 1.00 15.43 ? 1265 HOH A O 1 HETATM 8525 O O . HOH F 6 . ? 21.006 79.477 -23.702 1.00 19.07 ? 1266 HOH A O 1 HETATM 8526 O O . HOH F 6 . ? 19.305 79.209 -25.642 1.00 32.83 ? 1267 HOH A O 1 HETATM 8527 O O . HOH F 6 . ? 19.354 81.839 -27.525 1.00 38.15 ? 1268 HOH A O 1 HETATM 8528 O O . HOH F 6 . ? 19.046 83.398 -25.853 1.00 31.43 ? 1269 HOH A O 1 HETATM 8529 O O . HOH F 6 . ? 21.327 86.088 -31.004 1.00 34.30 ? 1270 HOH A O 1 HETATM 8530 O O . HOH F 6 . ? 23.225 87.008 -32.743 1.00 27.33 ? 1271 HOH A O 1 HETATM 8531 O O . HOH F 6 . ? 25.625 86.260 -32.010 1.00 16.46 ? 1272 HOH A O 1 HETATM 8532 O O . HOH F 6 . ? 27.139 89.787 -31.800 1.00 38.35 ? 1273 HOH A O 1 HETATM 8533 O O . HOH F 6 . ? 25.874 91.786 -32.316 1.00 38.39 ? 1274 HOH A O 1 HETATM 8534 O O . HOH F 6 . ? 26.680 91.747 -27.509 1.00 27.69 ? 1275 HOH A O 1 HETATM 8535 O O . HOH F 6 . ? 28.069 90.924 -25.311 1.00 19.11 ? 1276 HOH A O 1 HETATM 8536 O O . HOH F 6 . ? 29.497 88.805 -26.268 1.00 10.18 ? 1277 HOH A O 1 HETATM 8537 O O . HOH F 6 . ? 26.833 87.916 -23.715 1.00 21.02 ? 1278 HOH A O 1 HETATM 8538 O O . HOH F 6 . ? 25.165 88.862 -25.549 1.00 29.39 ? 1279 HOH A O 1 HETATM 8539 O O . HOH F 6 . ? 23.718 90.983 -26.141 1.00 36.68 ? 1280 HOH A O 1 HETATM 8540 O O . HOH F 6 . ? 21.567 86.263 -19.338 1.00 26.86 ? 1281 HOH A O 1 HETATM 8541 O O . HOH F 6 . ? 22.970 85.307 -17.074 1.00 32.87 ? 1282 HOH A O 1 HETATM 8542 O O . HOH F 6 . ? 24.833 83.182 -17.015 1.00 19.59 ? 1283 HOH A O 1 HETATM 8543 O O . HOH F 6 . ? 19.671 84.309 -18.329 1.00 26.26 ? 1284 HOH A O 1 HETATM 8544 O O . HOH F 6 . ? 17.503 81.518 -17.290 1.00 38.75 ? 1285 HOH A O 1 HETATM 8545 O O . HOH F 6 . ? 18.733 80.758 -11.750 1.00 30.07 ? 1286 HOH A O 1 HETATM 8546 O O . HOH F 6 . ? 15.611 79.857 -11.937 1.00 33.23 ? 1287 HOH A O 1 HETATM 8547 O O . HOH F 6 . ? 15.622 77.427 -13.630 1.00 29.54 ? 1288 HOH A O 1 HETATM 8548 O O . HOH F 6 . ? 15.754 75.377 -11.843 1.00 18.08 ? 1289 HOH A O 1 HETATM 8549 O O . HOH F 6 . ? 12.197 75.200 -13.534 1.00 26.84 ? 1290 HOH A O 1 HETATM 8550 O O . HOH F 6 . ? 12.753 74.873 -19.299 1.00 32.13 ? 1291 HOH A O 1 HETATM 8551 O O . HOH F 6 . ? 16.019 72.119 -19.006 1.00 15.19 ? 1292 HOH A O 1 HETATM 8552 O O . HOH F 6 . ? 17.024 70.391 -16.381 1.00 9.62 ? 1293 HOH A O 1 HETATM 8553 O O . HOH F 6 . ? 16.419 67.948 -19.871 1.00 16.03 ? 1294 HOH A O 1 HETATM 8554 O O . HOH F 6 . ? 20.446 66.235 -19.663 1.00 10.86 ? 1295 HOH A O 1 HETATM 8555 O O . HOH F 6 . ? 14.337 63.920 -16.392 1.00 12.75 ? 1296 HOH A O 1 HETATM 8556 O O . HOH F 6 . ? 14.427 61.961 -14.469 1.00 18.85 ? 1297 HOH A O 1 HETATM 8557 O O . HOH F 6 . ? 14.126 62.961 -12.161 1.00 19.45 ? 1298 HOH A O 1 HETATM 8558 O O . HOH F 6 . ? 12.377 64.750 -12.398 1.00 33.16 ? 1299 HOH A O 1 HETATM 8559 O O . HOH F 6 . ? 10.571 62.570 -12.190 1.00 29.53 ? 1300 HOH A O 1 HETATM 8560 O O . HOH F 6 . ? 10.189 62.864 -14.780 1.00 37.79 ? 1301 HOH A O 1 HETATM 8561 O O . HOH F 6 . ? 8.675 65.081 -14.951 1.00 28.01 ? 1302 HOH A O 1 HETATM 8562 O O . HOH F 6 . ? 11.600 63.524 -16.888 1.00 21.70 ? 1303 HOH A O 1 HETATM 8563 O O . HOH F 6 . ? 11.287 61.232 -18.392 1.00 19.02 ? 1304 HOH A O 1 HETATM 8564 O O . HOH F 6 . ? 13.307 62.352 -19.969 1.00 14.52 ? 1305 HOH A O 1 HETATM 8565 O O . HOH F 6 . ? 13.761 60.787 -22.430 1.00 12.75 ? 1306 HOH A O 1 HETATM 8566 O O . HOH F 6 . ? 12.073 61.272 -24.284 1.00 19.64 ? 1307 HOH A O 1 HETATM 8567 O O . HOH F 6 . ? 14.847 63.728 -25.834 1.00 18.74 ? 1308 HOH A O 1 HETATM 8568 O O . HOH F 6 . ? 16.628 60.638 -28.220 1.00 13.52 ? 1309 HOH A O 1 HETATM 8569 O O . HOH F 6 . ? 14.706 54.565 -26.328 1.00 24.47 ? 1310 HOH A O 1 HETATM 8570 O O . HOH F 6 . ? 16.358 52.916 -22.578 1.00 26.95 ? 1311 HOH A O 1 HETATM 8571 O O . HOH F 6 . ? 16.855 50.743 -19.418 1.00 19.91 ? 1312 HOH A O 1 HETATM 8572 O O . HOH F 6 . ? 18.293 48.709 -19.930 1.00 33.38 ? 1313 HOH A O 1 HETATM 8573 O O . HOH F 6 . ? 21.306 46.713 -17.517 1.00 27.28 ? 1314 HOH A O 1 HETATM 8574 O O . HOH F 6 . ? 23.491 45.988 -15.920 1.00 20.62 ? 1315 HOH A O 1 HETATM 8575 O O . HOH F 6 . ? 22.539 45.307 -13.505 1.00 18.75 ? 1316 HOH A O 1 HETATM 8576 O O . HOH F 6 . ? 21.884 42.684 -13.202 1.00 29.10 ? 1317 HOH A O 1 HETATM 8577 O O . HOH F 6 . ? 24.056 42.149 -14.408 1.00 23.83 ? 1318 HOH A O 1 HETATM 8578 O O . HOH F 6 . ? 26.633 41.583 -13.205 1.00 11.80 ? 1319 HOH A O 1 HETATM 8579 O O . HOH F 6 . ? 28.747 42.737 -11.896 1.00 9.96 ? 1320 HOH A O 1 HETATM 8580 O O . HOH F 6 . ? 24.262 39.049 -11.480 1.00 23.42 ? 1321 HOH A O 1 HETATM 8581 O O . HOH F 6 . ? 22.171 40.690 -11.274 1.00 28.74 ? 1322 HOH A O 1 HETATM 8582 O O . HOH F 6 . ? 21.759 40.380 -8.760 1.00 27.42 ? 1323 HOH A O 1 HETATM 8583 O O . HOH F 6 . ? 20.572 42.679 -7.426 1.00 20.48 ? 1324 HOH A O 1 HETATM 8584 O O . HOH F 6 . ? 19.569 41.581 -4.961 1.00 24.77 ? 1325 HOH A O 1 HETATM 8585 O O . HOH F 6 . ? 19.099 42.792 -2.530 1.00 28.04 ? 1326 HOH A O 1 HETATM 8586 O O . HOH F 6 . ? 16.506 43.049 -2.428 1.00 29.79 ? 1327 HOH A O 1 HETATM 8587 O O . HOH F 6 . ? 13.318 48.334 1.460 1.00 29.01 ? 1328 HOH A O 1 HETATM 8588 O O . HOH F 6 . ? 14.267 50.846 1.027 1.00 26.29 ? 1329 HOH A O 1 HETATM 8589 O O . HOH F 6 . ? 13.330 50.955 -1.670 1.00 21.13 ? 1330 HOH A O 1 HETATM 8590 O O . HOH F 6 . ? 11.522 48.636 -2.450 1.00 30.26 ? 1331 HOH A O 1 HETATM 8591 O O . HOH F 6 . ? 10.267 51.277 -0.597 1.00 21.93 ? 1332 HOH A O 1 HETATM 8592 O O . HOH F 6 . ? 10.360 51.886 2.314 1.00 32.13 ? 1333 HOH A O 1 HETATM 8593 O O . HOH F 6 . ? 13.298 53.603 1.767 1.00 15.56 ? 1334 HOH A O 1 HETATM 8594 O O . HOH F 6 . ? 13.705 54.219 4.371 1.00 13.37 ? 1335 HOH A O 1 HETATM 8595 O O . HOH F 6 . ? 12.282 56.328 5.348 1.00 13.81 ? 1336 HOH A O 1 HETATM 8596 O O . HOH F 6 . ? 11.553 58.789 7.734 1.00 24.06 ? 1337 HOH A O 1 HETATM 8597 O O . HOH F 6 . ? 9.687 59.998 6.581 1.00 39.25 ? 1338 HOH A O 1 HETATM 8598 O O . HOH F 6 . ? 13.594 60.883 7.741 1.00 24.27 ? 1339 HOH A O 1 HETATM 8599 O O . HOH F 6 . ? 14.310 60.133 5.189 1.00 11.83 ? 1340 HOH A O 1 HETATM 8600 O O . HOH F 6 . ? 10.145 62.269 2.141 1.00 30.60 ? 1341 HOH A O 1 HETATM 8601 O O . HOH F 6 . ? 7.538 58.358 -0.079 1.00 27.49 ? 1342 HOH A O 1 HETATM 8602 O O . HOH F 6 . ? 10.124 58.066 -3.342 1.00 27.52 ? 1343 HOH A O 1 HETATM 8603 O O . HOH F 6 . ? 11.604 59.612 -5.031 1.00 17.54 ? 1344 HOH A O 1 HETATM 8604 O O . HOH F 6 . ? 13.945 59.896 -3.440 1.00 13.27 ? 1345 HOH A O 1 HETATM 8605 O O . HOH F 6 . ? 12.676 62.095 -2.440 1.00 24.33 ? 1346 HOH A O 1 HETATM 8606 O O . HOH F 6 . ? 13.878 58.063 -1.399 1.00 18.68 ? 1347 HOH A O 1 HETATM 8607 O O . HOH F 6 . ? 8.688 55.084 -6.086 1.00 20.42 ? 1348 HOH A O 1 HETATM 8608 O O . HOH F 6 . ? 7.974 53.119 -7.699 1.00 29.20 ? 1349 HOH A O 1 HETATM 8609 O O . HOH F 6 . ? 7.308 54.449 -10.090 1.00 31.14 ? 1350 HOH A O 1 HETATM 8610 O O . HOH F 6 . ? 8.482 57.704 -6.840 1.00 20.74 ? 1351 HOH A O 1 HETATM 8611 O O . HOH F 6 . ? 4.266 56.294 -6.568 1.00 23.46 ? 1352 HOH A O 1 HETATM 8612 O O . HOH F 6 . ? 11.726 55.044 -12.395 1.00 15.93 ? 1353 HOH A O 1 HETATM 8613 O O . HOH F 6 . ? 12.130 55.780 -15.111 1.00 18.62 ? 1354 HOH A O 1 HETATM 8614 O O . HOH F 6 . ? 14.184 54.368 -16.192 1.00 15.52 ? 1355 HOH A O 1 HETATM 8615 O O . HOH F 6 . ? 13.256 52.020 -15.167 1.00 29.99 ? 1356 HOH A O 1 HETATM 8616 O O . HOH F 6 . ? 12.603 51.786 -12.029 1.00 28.52 ? 1357 HOH A O 1 HETATM 8617 O O . HOH F 6 . ? 18.486 51.064 -12.466 1.00 10.36 ? 1358 HOH A O 1 HETATM 8618 O O . HOH F 6 . ? 19.548 53.543 -11.806 1.00 10.16 ? 1359 HOH A O 1 HETATM 8619 O O . HOH F 6 . ? 22.190 54.401 -12.034 1.00 9.64 ? 1360 HOH A O 1 HETATM 8620 O O . HOH F 6 . ? 24.613 52.956 -11.779 1.00 7.88 ? 1361 HOH A O 1 HETATM 8621 O O . HOH F 6 . ? 25.476 51.256 -9.517 1.00 10.49 ? 1362 HOH A O 1 HETATM 8622 O O . HOH F 6 . ? 22.859 51.801 -8.622 1.00 15.16 ? 1363 HOH A O 1 HETATM 8623 O O . HOH F 6 . ? 24.038 53.230 -6.275 1.00 17.07 ? 1364 HOH A O 1 HETATM 8624 O O . HOH F 6 . ? 23.217 54.021 -3.652 1.00 11.73 ? 1365 HOH A O 1 HETATM 8625 O O . HOH F 6 . ? 24.234 55.735 -1.800 1.00 11.41 ? 1366 HOH A O 1 HETATM 8626 O O . HOH F 6 . ? 20.473 57.435 -5.304 1.00 8.97 ? 1367 HOH A O 1 HETATM 8627 O O . HOH F 6 . ? 21.420 58.001 -7.852 1.00 8.51 ? 1368 HOH A O 1 HETATM 8628 O O . HOH F 6 . ? 19.715 57.448 -11.827 1.00 12.87 ? 1369 HOH A O 1 HETATM 8629 O O . HOH F 6 . ? 25.986 49.626 -13.704 1.00 8.36 ? 1370 HOH A O 1 HETATM 8630 O O . HOH F 6 . ? 26.159 48.935 -10.977 1.00 9.27 ? 1371 HOH A O 1 HETATM 8631 O O . HOH F 6 . ? 31.637 47.047 -8.071 1.00 7.28 ? 1372 HOH A O 1 HETATM 8632 O O . HOH F 6 . ? 33.372 48.131 -10.126 1.00 7.65 ? 1373 HOH A O 1 HETATM 8633 O O . HOH F 6 . ? 35.024 48.256 -16.418 1.00 32.30 ? 1374 HOH A O 1 HETATM 8634 O O . HOH F 6 . ? 35.075 50.582 -17.603 1.00 12.86 ? 1375 HOH A O 1 HETATM 8635 O O . HOH F 6 . ? 37.478 51.558 -18.542 1.00 16.88 ? 1376 HOH A O 1 HETATM 8636 O O . HOH F 6 . ? 37.515 52.138 -21.154 1.00 10.08 ? 1377 HOH A O 1 HETATM 8637 O O . HOH F 6 . ? 39.574 53.953 -20.803 1.00 12.56 ? 1378 HOH A O 1 HETATM 8638 O O . HOH F 6 . ? 39.958 56.242 -19.148 1.00 23.38 ? 1379 HOH A O 1 HETATM 8639 O O . HOH F 6 . ? 41.400 54.837 -17.248 1.00 27.96 ? 1380 HOH A O 1 HETATM 8640 O O . HOH F 6 . ? 40.944 52.278 -16.909 1.00 12.39 ? 1381 HOH A O 1 HETATM 8641 O O . HOH F 6 . ? 38.436 54.294 -17.546 1.00 29.50 ? 1382 HOH A O 1 HETATM 8642 O O . HOH F 6 . ? 39.577 58.892 -18.089 1.00 20.15 ? 1383 HOH A O 1 HETATM 8643 O O . HOH F 6 . ? 41.618 58.685 -16.054 1.00 13.96 ? 1384 HOH A O 1 HETATM 8644 O O . HOH F 6 . ? 44.450 58.755 -15.997 1.00 14.67 ? 1385 HOH A O 1 HETATM 8645 O O . HOH F 6 . ? 44.412 56.057 -15.391 1.00 15.52 ? 1386 HOH A O 1 HETATM 8646 O O . HOH F 6 . ? 47.223 55.776 -15.366 1.00 14.60 ? 1387 HOH A O 1 HETATM 8647 O O . HOH F 6 . ? 46.518 57.345 -18.750 1.00 12.42 ? 1388 HOH A O 1 HETATM 8648 O O . HOH F 6 . ? 45.621 59.975 -18.321 1.00 11.95 ? 1389 HOH A O 1 HETATM 8649 O O . HOH F 6 . ? 42.896 59.545 -18.876 1.00 21.79 ? 1390 HOH A O 1 HETATM 8650 O O . HOH F 6 . ? 44.628 54.953 -18.043 1.00 17.95 ? 1391 HOH A O 1 HETATM 8651 O O . HOH F 6 . ? 45.879 52.725 -19.153 1.00 18.15 ? 1392 HOH A O 1 HETATM 8652 O O . HOH F 6 . ? 46.548 53.919 -20.925 1.00 26.90 ? 1393 HOH A O 1 HETATM 8653 O O . HOH F 6 . ? 48.507 54.884 -22.769 1.00 14.72 ? 1394 HOH A O 1 HETATM 8654 O O . HOH F 6 . ? 46.809 55.809 -25.495 1.00 13.86 ? 1395 HOH A O 1 HETATM 8655 O O . HOH F 6 . ? 43.813 54.967 -26.818 1.00 26.64 ? 1396 HOH A O 1 HETATM 8656 O O . HOH F 6 . ? 49.727 55.035 -29.105 1.00 14.88 ? 1397 HOH A O 1 HETATM 8657 O O . HOH F 6 . ? 51.062 52.712 -28.719 1.00 16.66 ? 1398 HOH A O 1 HETATM 8658 O O . HOH F 6 . ? 53.365 53.223 -30.191 1.00 25.01 ? 1399 HOH A O 1 HETATM 8659 O O . HOH F 6 . ? 53.088 54.984 -31.974 1.00 32.49 ? 1400 HOH A O 1 HETATM 8660 O O . HOH F 6 . ? 51.959 56.286 -30.364 1.00 19.51 ? 1401 HOH A O 1 HETATM 8661 O O . HOH F 6 . ? 48.819 50.747 -29.605 1.00 19.89 ? 1402 HOH A O 1 HETATM 8662 O O . HOH F 6 . ? 49.862 46.685 -30.700 1.00 28.91 ? 1403 HOH A O 1 HETATM 8663 O O . HOH F 6 . ? 52.474 45.429 -27.279 1.00 27.42 ? 1404 HOH A O 1 HETATM 8664 O O . HOH F 6 . ? 53.167 47.015 -25.082 1.00 16.36 ? 1405 HOH A O 1 HETATM 8665 O O . HOH F 6 . ? 50.385 45.019 -24.826 1.00 23.10 ? 1406 HOH A O 1 HETATM 8666 O O . HOH F 6 . ? 53.782 40.629 -20.498 1.00 33.17 ? 1407 HOH A O 1 HETATM 8667 O O . HOH F 6 . ? 56.838 38.954 -19.337 1.00 32.30 ? 1408 HOH A O 1 HETATM 8668 O O . HOH F 6 . ? 56.870 43.107 -20.000 1.00 20.25 ? 1409 HOH A O 1 HETATM 8669 O O . HOH F 6 . ? 56.436 46.127 -17.333 1.00 13.22 ? 1410 HOH A O 1 HETATM 8670 O O . HOH F 6 . ? 62.069 48.104 -20.969 1.00 36.43 ? 1411 HOH A O 1 HETATM 8671 O O . HOH F 6 . ? 62.828 42.693 -20.968 1.00 27.05 ? 1412 HOH A O 1 HETATM 8672 O O . HOH F 6 . ? 68.922 41.575 -17.017 1.00 34.68 ? 1413 HOH A O 1 HETATM 8673 O O . HOH F 6 . ? 70.901 43.040 -15.264 1.00 29.28 ? 1414 HOH A O 1 HETATM 8674 O O . HOH F 6 . ? 72.863 43.143 -12.453 1.00 46.15 ? 1415 HOH A O 1 HETATM 8675 O O . HOH F 6 . ? 72.089 47.264 -17.893 1.00 32.74 ? 1416 HOH A O 1 HETATM 8676 O O . HOH F 6 . ? 68.543 46.973 -16.633 1.00 31.30 ? 1417 HOH A O 1 HETATM 8677 O O . HOH F 6 . ? 63.722 50.078 -13.975 1.00 11.78 ? 1418 HOH A O 1 HETATM 8678 O O . HOH F 6 . ? 70.483 52.195 -12.518 1.00 20.28 ? 1419 HOH A O 1 HETATM 8679 O O . HOH F 6 . ? 69.845 53.440 -10.377 1.00 33.71 ? 1420 HOH A O 1 HETATM 8680 O O . HOH F 6 . ? 70.091 56.286 -12.491 1.00 33.03 ? 1421 HOH A O 1 HETATM 8681 O O . HOH F 6 . ? 72.144 58.786 -11.326 1.00 20.31 ? 1422 HOH A O 1 HETATM 8682 O O . HOH F 6 . ? 74.269 60.037 -9.605 1.00 33.18 ? 1423 HOH A O 1 HETATM 8683 O O . HOH F 6 . ? 72.971 65.011 -7.747 1.00 18.46 ? 1424 HOH A O 1 HETATM 8684 O O . HOH F 6 . ? 73.067 66.426 -10.124 1.00 18.55 ? 1425 HOH A O 1 HETATM 8685 O O . HOH F 6 . ? 77.514 66.229 -11.946 1.00 34.85 ? 1426 HOH A O 1 HETATM 8686 O O . HOH F 6 . ? 78.581 68.589 -12.505 1.00 31.48 ? 1427 HOH A O 1 HETATM 8687 O O . HOH F 6 . ? 78.998 70.030 -10.405 1.00 35.12 ? 1428 HOH A O 1 HETATM 8688 O O . HOH F 6 . ? 81.013 68.661 -11.451 1.00 24.86 ? 1429 HOH A O 1 HETATM 8689 O O . HOH F 6 . ? 81.412 67.165 -13.556 1.00 19.87 ? 1430 HOH A O 1 HETATM 8690 O O . HOH F 6 . ? 83.250 66.445 -15.380 1.00 16.47 ? 1431 HOH A O 1 HETATM 8691 O O . HOH F 6 . ? 84.119 68.295 -17.301 1.00 12.88 ? 1432 HOH A O 1 HETATM 8692 O O . HOH F 6 . ? 83.341 70.208 -20.277 1.00 19.53 ? 1433 HOH A O 1 HETATM 8693 O O . HOH F 6 . ? 83.340 67.614 -22.940 1.00 20.90 ? 1434 HOH A O 1 HETATM 8694 O O . HOH F 6 . ? 80.251 64.042 -21.359 1.00 16.24 ? 1435 HOH A O 1 HETATM 8695 O O . HOH F 6 . ? 78.747 62.384 -22.961 1.00 29.29 ? 1436 HOH A O 1 HETATM 8696 O O . HOH F 6 . ? 72.723 63.915 -21.155 1.00 24.95 ? 1437 HOH A O 1 HETATM 8697 O O . HOH F 6 . ? 70.155 61.772 -20.486 1.00 31.22 ? 1438 HOH A O 1 HETATM 8698 O O . HOH F 6 . ? 71.707 62.601 -18.107 1.00 28.74 ? 1439 HOH A O 1 HETATM 8699 O O . HOH F 6 . ? 73.877 65.811 -17.660 1.00 13.38 ? 1440 HOH A O 1 HETATM 8700 O O . HOH F 6 . ? 74.608 64.349 -15.496 1.00 31.35 ? 1441 HOH A O 1 HETATM 8701 O O . HOH F 6 . ? 69.977 69.836 -12.592 1.00 11.73 ? 1442 HOH A O 1 HETATM 8702 O O . HOH F 6 . ? 66.472 71.483 -6.851 1.00 18.97 ? 1443 HOH A O 1 HETATM 8703 O O . HOH F 6 . ? 64.066 70.659 -5.336 1.00 14.97 ? 1444 HOH A O 1 HETATM 8704 O O . HOH F 6 . ? 66.708 74.482 -4.461 1.00 24.66 ? 1445 HOH A O 1 HETATM 8705 O O . HOH F 6 . ? 65.344 76.926 -3.654 1.00 26.95 ? 1446 HOH A O 1 HETATM 8706 O O . HOH F 6 . ? 65.437 78.662 -5.740 1.00 27.07 ? 1447 HOH A O 1 HETATM 8707 O O . HOH F 6 . ? 65.209 79.772 -8.963 1.00 32.97 ? 1448 HOH A O 1 HETATM 8708 O O . HOH F 6 . ? 66.942 81.326 -11.396 1.00 29.00 ? 1449 HOH A O 1 HETATM 8709 O O . HOH F 6 . ? 66.396 81.746 -14.295 1.00 26.85 ? 1450 HOH A O 1 HETATM 8710 O O . HOH F 6 . ? 63.538 82.016 -14.380 1.00 36.81 ? 1451 HOH A O 1 HETATM 8711 O O . HOH F 6 . ? 62.220 82.869 -17.409 1.00 40.43 ? 1452 HOH A O 1 HETATM 8712 O O . HOH F 6 . ? 61.982 80.738 -18.901 1.00 23.58 ? 1453 HOH A O 1 HETATM 8713 O O . HOH F 6 . ? 62.860 83.199 -21.175 1.00 41.45 ? 1454 HOH A O 1 HETATM 8714 O O . HOH F 6 . ? 62.430 85.241 -23.094 1.00 26.12 ? 1455 HOH A O 1 HETATM 8715 O O . HOH F 6 . ? 65.662 84.781 -22.659 1.00 30.47 ? 1456 HOH A O 1 HETATM 8716 O O . HOH F 6 . ? 65.160 87.810 -24.152 1.00 22.97 ? 1457 HOH A O 1 HETATM 8717 O O . HOH F 6 . ? 67.801 88.165 -23.553 1.00 23.99 ? 1458 HOH A O 1 HETATM 8718 O O . HOH F 6 . ? 71.687 84.558 -20.162 1.00 28.09 ? 1459 HOH A O 1 HETATM 8719 O O . HOH F 6 . ? 73.310 82.298 -21.191 1.00 25.08 ? 1460 HOH A O 1 HETATM 8720 O O . HOH F 6 . ? 74.408 76.789 -20.200 1.00 29.59 ? 1461 HOH A O 1 HETATM 8721 O O . HOH F 6 . ? 73.044 76.758 -18.262 1.00 33.68 ? 1462 HOH A O 1 HETATM 8722 O O . HOH F 6 . ? 75.207 74.069 -19.402 1.00 16.79 ? 1463 HOH A O 1 HETATM 8723 O O . HOH F 6 . ? 77.680 74.969 -18.629 1.00 39.76 ? 1464 HOH A O 1 HETATM 8724 O O . HOH F 6 . ? 79.728 73.963 -17.853 1.00 23.88 ? 1465 HOH A O 1 HETATM 8725 O O . HOH F 6 . ? 74.634 76.702 -13.937 1.00 25.53 ? 1466 HOH A O 1 HETATM 8726 O O . HOH F 6 . ? 74.039 80.154 -11.023 1.00 40.84 ? 1467 HOH A O 1 HETATM 8727 O O . HOH F 6 . ? 75.342 75.989 -5.853 1.00 38.48 ? 1468 HOH A O 1 HETATM 8728 O O . HOH F 6 . ? 73.714 74.029 -5.710 1.00 21.52 ? 1469 HOH A O 1 HETATM 8729 O O . HOH F 6 . ? 77.846 72.500 -10.479 1.00 25.49 ? 1470 HOH A O 1 HETATM 8730 O O . HOH F 6 . ? 68.533 78.898 -18.030 1.00 23.97 ? 1471 HOH A O 1 HETATM 8731 O O . HOH F 6 . ? 67.745 78.871 -25.372 1.00 10.43 ? 1472 HOH A O 1 HETATM 8732 O O . HOH F 6 . ? 67.748 81.643 -25.722 1.00 10.50 ? 1473 HOH A O 1 HETATM 8733 O O . HOH F 6 . ? 68.306 79.361 -28.610 1.00 14.95 ? 1474 HOH A O 1 HETATM 8734 O O . HOH F 6 . ? 70.770 80.451 -27.732 1.00 35.60 ? 1475 HOH A O 1 HETATM 8735 O O . HOH F 6 . ? 70.530 78.060 -26.240 1.00 18.27 ? 1476 HOH A O 1 HETATM 8736 O O . HOH F 6 . ? 72.232 75.881 -27.077 1.00 30.31 ? 1477 HOH A O 1 HETATM 8737 O O . HOH F 6 . ? 71.688 73.674 -29.207 1.00 24.72 ? 1478 HOH A O 1 HETATM 8738 O O . HOH F 6 . ? 76.589 74.043 -26.755 1.00 28.04 ? 1479 HOH A O 1 HETATM 8739 O O . HOH F 6 . ? 69.273 76.984 -34.113 1.00 26.02 ? 1480 HOH A O 1 HETATM 8740 O O . HOH F 6 . ? 67.937 75.046 -35.147 1.00 27.12 ? 1481 HOH A O 1 HETATM 8741 O O . HOH F 6 . ? 67.914 77.132 -38.612 1.00 39.65 ? 1482 HOH A O 1 HETATM 8742 O O . HOH F 6 . ? 69.931 74.040 -40.021 1.00 60.30 ? 1483 HOH A O 1 HETATM 8743 O O . HOH F 6 . ? 63.995 78.551 -38.027 1.00 26.82 ? 1484 HOH A O 1 HETATM 8744 O O . HOH F 6 . ? 64.249 77.825 -35.417 1.00 12.29 ? 1485 HOH A O 1 HETATM 8745 O O . HOH F 6 . ? 68.298 79.560 -34.864 1.00 23.86 ? 1486 HOH A O 1 HETATM 8746 O O . HOH F 6 . ? 69.671 82.044 -34.133 1.00 32.76 ? 1487 HOH A O 1 HETATM 8747 O O . HOH F 6 . ? 69.407 83.723 -36.138 1.00 29.49 ? 1488 HOH A O 1 HETATM 8748 O O . HOH F 6 . ? 67.361 85.584 -36.481 1.00 30.55 ? 1489 HOH A O 1 HETATM 8749 O O . HOH F 6 . ? 68.077 88.116 -35.332 1.00 31.72 ? 1490 HOH A O 1 HETATM 8750 O O . HOH F 6 . ? 65.478 87.506 -41.427 1.00 39.09 ? 1491 HOH A O 1 HETATM 8751 O O . HOH F 6 . ? 61.745 83.098 -38.399 1.00 25.56 ? 1492 HOH A O 1 HETATM 8752 O O . HOH F 6 . ? 60.620 78.811 -41.665 1.00 27.46 ? 1493 HOH A O 1 HETATM 8753 O O . HOH F 6 . ? 61.304 76.620 -39.888 1.00 18.13 ? 1494 HOH A O 1 HETATM 8754 O O . HOH F 6 . ? 58.353 77.198 -38.636 1.00 12.05 ? 1495 HOH A O 1 HETATM 8755 O O . HOH F 6 . ? 51.308 76.208 -40.946 1.00 22.43 ? 1496 HOH A O 1 HETATM 8756 O O . HOH F 6 . ? 47.453 78.989 -40.624 1.00 16.91 ? 1497 HOH A O 1 HETATM 8757 O O . HOH F 6 . ? 46.489 80.298 -42.759 1.00 28.11 ? 1498 HOH A O 1 HETATM 8758 O O . HOH F 6 . ? 43.865 79.909 -42.640 1.00 29.99 ? 1499 HOH A O 1 HETATM 8759 O O . HOH F 6 . ? 44.825 82.983 -43.422 1.00 38.25 ? 1500 HOH A O 1 HETATM 8760 O O . HOH F 6 . ? 49.845 82.372 -44.061 1.00 16.51 ? 1501 HOH A O 1 HETATM 8761 O O . HOH F 6 . ? 54.269 82.616 -44.792 1.00 45.08 ? 1502 HOH A O 1 HETATM 8762 O O . HOH F 6 . ? 59.208 86.977 -45.913 1.00 38.58 ? 1503 HOH A O 1 HETATM 8763 O O . HOH F 6 . ? 56.623 89.809 -43.797 1.00 32.25 ? 1504 HOH A O 1 HETATM 8764 O O . HOH F 6 . ? 53.638 92.732 -40.936 1.00 37.39 ? 1505 HOH A O 1 HETATM 8765 O O . HOH F 6 . ? 61.082 92.803 -39.034 1.00 49.76 ? 1506 HOH A O 1 HETATM 8766 O O . HOH F 6 . ? 61.503 90.697 -37.136 1.00 47.13 ? 1507 HOH A O 1 HETATM 8767 O O . HOH F 6 . ? 59.568 91.171 -35.504 1.00 23.11 ? 1508 HOH A O 1 HETATM 8768 O O . HOH F 6 . ? 60.286 91.097 -31.389 1.00 25.75 ? 1509 HOH A O 1 HETATM 8769 O O . HOH F 6 . ? 60.514 91.847 -28.432 1.00 25.44 ? 1510 HOH A O 1 HETATM 8770 O O . HOH F 6 . ? 58.434 92.997 -26.851 1.00 28.74 ? 1511 HOH A O 1 HETATM 8771 O O . HOH F 6 . ? 58.154 93.214 -24.587 1.00 24.41 ? 1512 HOH A O 1 HETATM 8772 O O . HOH F 6 . ? 56.330 91.000 -25.748 1.00 21.26 ? 1513 HOH A O 1 HETATM 8773 O O . HOH F 6 . ? 54.949 90.228 -23.467 1.00 32.23 ? 1514 HOH A O 1 HETATM 8774 O O . HOH F 6 . ? 52.688 91.980 -23.384 1.00 30.08 ? 1515 HOH A O 1 HETATM 8775 O O . HOH F 6 . ? 54.240 93.516 -25.037 1.00 35.44 ? 1516 HOH A O 1 HETATM 8776 O O . HOH F 6 . ? 49.522 92.153 -25.017 1.00 30.47 ? 1517 HOH A O 1 HETATM 8777 O O . HOH F 6 . ? 50.835 90.650 -21.574 1.00 35.86 ? 1518 HOH A O 1 HETATM 8778 O O . HOH F 6 . ? 53.118 86.859 -21.370 1.00 25.69 ? 1519 HOH A O 1 HETATM 8779 O O . HOH F 6 . ? 56.615 87.588 -19.931 1.00 30.47 ? 1520 HOH A O 1 HETATM 8780 O O . HOH F 6 . ? 54.884 80.523 -19.327 1.00 26.85 ? 1521 HOH A O 1 HETATM 8781 O O . HOH F 6 . ? 52.541 79.019 -17.503 1.00 19.80 ? 1522 HOH A O 1 HETATM 8782 O O . HOH F 6 . ? 50.548 79.062 -15.638 1.00 21.43 ? 1523 HOH A O 1 HETATM 8783 O O . HOH F 6 . ? 47.416 79.618 -18.475 1.00 19.44 ? 1524 HOH A O 1 HETATM 8784 O O . HOH F 6 . ? 47.279 81.430 -17.077 1.00 24.13 ? 1525 HOH A O 1 HETATM 8785 O O . HOH F 6 . ? 49.656 84.077 -19.002 1.00 29.72 ? 1526 HOH A O 1 HETATM 8786 O O . HOH F 6 . ? 45.714 85.206 -19.036 1.00 34.08 ? 1527 HOH A O 1 HETATM 8787 O O . HOH F 6 . ? 46.986 89.679 -23.463 1.00 37.07 ? 1528 HOH A O 1 HETATM 8788 O O . HOH F 6 . ? 45.238 90.086 -25.630 1.00 18.81 ? 1529 HOH A O 1 HETATM 8789 O O . HOH F 6 . ? 44.880 92.560 -25.286 1.00 34.74 ? 1530 HOH A O 1 HETATM 8790 O O . HOH F 6 . ? 45.683 95.166 -26.838 1.00 33.25 ? 1531 HOH A O 1 HETATM 8791 O O . HOH F 6 . ? 44.404 95.494 -30.672 1.00 27.66 ? 1532 HOH A O 1 HETATM 8792 O O . HOH F 6 . ? 42.142 94.695 -29.930 1.00 32.02 ? 1533 HOH A O 1 HETATM 8793 O O . HOH F 6 . ? 36.385 93.728 -29.484 1.00 37.80 ? 1534 HOH A O 1 HETATM 8794 O O . HOH F 6 . ? 34.266 93.505 -30.470 1.00 28.16 ? 1535 HOH A O 1 HETATM 8795 O O . HOH F 6 . ? 34.985 94.792 -32.806 1.00 29.00 ? 1536 HOH A O 1 HETATM 8796 O O . HOH F 6 . ? 31.689 92.481 -36.931 1.00 21.96 ? 1537 HOH A O 1 HETATM 8797 O O . HOH F 6 . ? 28.575 93.813 -38.507 1.00 21.13 ? 1538 HOH A O 1 HETATM 8798 O O . HOH F 6 . ? 28.408 90.461 -42.929 1.00 28.34 ? 1539 HOH A O 1 HETATM 8799 O O . HOH F 6 . ? 28.176 87.968 -41.794 1.00 22.39 ? 1540 HOH A O 1 HETATM 8800 O O . HOH F 6 . ? 25.677 87.724 -42.965 1.00 35.40 ? 1541 HOH A O 1 HETATM 8801 O O . HOH F 6 . ? 23.110 88.755 -38.030 1.00 29.06 ? 1542 HOH A O 1 HETATM 8802 O O . HOH F 6 . ? 23.278 82.591 -40.734 1.00 21.10 ? 1543 HOH A O 1 HETATM 8803 O O . HOH F 6 . ? 22.182 80.700 -42.458 1.00 30.54 ? 1544 HOH A O 1 HETATM 8804 O O . HOH F 6 . ? 19.512 81.757 -42.515 1.00 38.48 ? 1545 HOH A O 1 HETATM 8805 O O . HOH F 6 . ? 21.260 82.065 -38.153 1.00 32.92 ? 1546 HOH A O 1 HETATM 8806 O O . HOH F 6 . ? 21.936 80.268 -36.098 1.00 21.66 ? 1547 HOH A O 1 HETATM 8807 O O . HOH F 6 . ? 20.437 80.479 -33.793 1.00 41.22 ? 1548 HOH A O 1 HETATM 8808 O O . HOH F 6 . ? 28.886 81.844 -35.771 1.00 15.06 ? 1549 HOH A O 1 HETATM 8809 O O . HOH F 6 . ? 27.991 84.638 -35.577 1.00 13.67 ? 1550 HOH A O 1 HETATM 8810 O O . HOH F 6 . ? 29.880 81.685 -43.118 1.00 40.85 ? 1551 HOH A O 1 HETATM 8811 O O . HOH F 6 . ? 31.293 79.102 -43.028 1.00 24.68 ? 1552 HOH A O 1 HETATM 8812 O O . HOH F 6 . ? 35.620 77.358 -43.101 1.00 30.77 ? 1553 HOH A O 1 HETATM 8813 O O . HOH F 6 . ? 37.565 75.601 -42.543 1.00 17.23 ? 1554 HOH A O 1 HETATM 8814 O O . HOH F 6 . ? 39.558 75.503 -40.394 1.00 15.66 ? 1555 HOH A O 1 HETATM 8815 O O . HOH F 6 . ? 42.160 74.677 -41.557 1.00 20.37 ? 1556 HOH A O 1 HETATM 8816 O O . HOH F 6 . ? 43.716 72.494 -42.028 1.00 17.95 ? 1557 HOH A O 1 HETATM 8817 O O . HOH F 6 . ? 44.625 72.084 -44.704 1.00 38.80 ? 1558 HOH A O 1 HETATM 8818 O O . HOH F 6 . ? 46.130 70.285 -39.851 1.00 27.85 ? 1559 HOH A O 1 HETATM 8819 O O . HOH F 6 . ? 46.484 70.277 -36.804 1.00 15.27 ? 1560 HOH A O 1 HETATM 8820 O O . HOH F 6 . ? 48.978 69.109 -37.110 1.00 23.76 ? 1561 HOH A O 1 HETATM 8821 O O . HOH F 6 . ? 51.596 70.052 -38.118 1.00 19.93 ? 1562 HOH A O 1 HETATM 8822 O O . HOH F 6 . ? 53.886 71.179 -36.925 1.00 11.99 ? 1563 HOH A O 1 HETATM 8823 O O . HOH F 6 . ? 55.245 68.990 -37.820 1.00 27.06 ? 1564 HOH A O 1 HETATM 8824 O O . HOH F 6 . ? 56.536 69.895 -39.967 1.00 25.43 ? 1565 HOH A O 1 HETATM 8825 O O . HOH F 6 . ? 60.139 68.585 -38.815 1.00 31.80 ? 1566 HOH A O 1 HETATM 8826 O O . HOH F 6 . ? 61.526 68.879 -41.756 1.00 33.99 ? 1567 HOH A O 1 HETATM 8827 O O . HOH F 6 . ? 59.280 67.163 -34.740 1.00 24.86 ? 1568 HOH A O 1 HETATM 8828 O O . HOH F 6 . ? 56.691 67.621 -35.578 1.00 20.41 ? 1569 HOH A O 1 HETATM 8829 O O . HOH F 6 . ? 56.046 65.012 -36.236 1.00 18.66 ? 1570 HOH A O 1 HETATM 8830 O O . HOH F 6 . ? 61.533 63.830 -30.970 1.00 28.83 ? 1571 HOH A O 1 HETATM 8831 O O . HOH F 6 . ? 63.757 65.493 -30.534 1.00 33.64 ? 1572 HOH A O 1 HETATM 8832 O O . HOH F 6 . ? 63.087 67.795 -31.784 1.00 25.29 ? 1573 HOH A O 1 HETATM 8833 O O . HOH F 6 . ? 69.599 63.822 -28.811 1.00 24.78 ? 1574 HOH A O 1 HETATM 8834 O O . HOH F 6 . ? 71.275 62.505 -27.142 1.00 42.53 ? 1575 HOH A O 1 HETATM 8835 O O . HOH F 6 . ? 69.763 62.740 -23.924 1.00 29.32 ? 1576 HOH A O 1 HETATM 8836 O O . HOH F 6 . ? 67.897 58.656 -24.162 1.00 17.64 ? 1577 HOH A O 1 HETATM 8837 O O . HOH F 6 . ? 67.889 57.217 -26.946 1.00 34.96 ? 1578 HOH A O 1 HETATM 8838 O O . HOH F 6 . ? 66.799 59.943 -27.192 1.00 18.68 ? 1579 HOH A O 1 HETATM 8839 O O . HOH F 6 . ? 66.490 56.163 -20.294 1.00 15.89 ? 1580 HOH A O 1 HETATM 8840 O O . HOH F 6 . ? 67.488 54.537 -18.313 1.00 24.85 ? 1581 HOH A O 1 HETATM 8841 O O . HOH F 6 . ? 68.648 56.808 -16.288 1.00 31.88 ? 1582 HOH A O 1 HETATM 8842 O O . HOH F 6 . ? 66.437 62.525 -13.218 1.00 18.63 ? 1583 HOH A O 1 HETATM 8843 O O . HOH F 6 . ? 65.599 60.269 -7.706 1.00 9.90 ? 1584 HOH A O 1 HETATM 8844 O O . HOH F 6 . ? 67.426 60.630 -5.694 1.00 11.39 ? 1585 HOH A O 1 HETATM 8845 O O . HOH F 6 . ? 68.811 58.222 -5.065 1.00 12.22 ? 1586 HOH A O 1 HETATM 8846 O O . HOH F 6 . ? 69.108 61.391 -2.367 1.00 13.47 ? 1587 HOH A O 1 HETATM 8847 O O . HOH F 6 . ? 67.947 65.519 -3.418 1.00 13.43 ? 1588 HOH A O 1 HETATM 8848 O O . HOH F 6 . ? 65.915 66.045 -0.511 1.00 21.33 ? 1589 HOH A O 1 HETATM 8849 O O . HOH F 6 . ? 62.390 60.656 0.473 1.00 28.36 ? 1590 HOH A O 1 HETATM 8850 O O . HOH F 6 . ? 63.109 58.587 -1.377 1.00 15.16 ? 1591 HOH A O 1 HETATM 8851 O O . HOH F 6 . ? 63.692 57.102 0.946 1.00 31.19 ? 1592 HOH A O 1 HETATM 8852 O O . HOH F 6 . ? 66.992 55.242 1.067 1.00 15.37 ? 1593 HOH A O 1 HETATM 8853 O O . HOH F 6 . ? 66.006 50.316 0.512 1.00 39.48 ? 1594 HOH A O 1 HETATM 8854 O O . HOH F 6 . ? 68.069 49.340 -0.901 1.00 19.62 ? 1595 HOH A O 1 HETATM 8855 O O . HOH F 6 . ? 67.441 46.559 -1.267 1.00 21.46 ? 1596 HOH A O 1 HETATM 8856 O O . HOH F 6 . ? 65.943 45.493 -3.077 1.00 26.49 ? 1597 HOH A O 1 HETATM 8857 O O . HOH F 6 . ? 63.016 44.941 -3.372 1.00 34.94 ? 1598 HOH A O 1 HETATM 8858 O O . HOH F 6 . ? 63.372 44.661 -6.599 1.00 15.34 ? 1599 HOH A O 1 HETATM 8859 O O . HOH F 6 . ? 64.237 39.271 -10.218 1.00 18.48 ? 1600 HOH A O 1 HETATM 8860 O O . HOH F 6 . ? 66.961 38.474 -9.595 1.00 30.94 ? 1601 HOH A O 1 HETATM 8861 O O . HOH F 6 . ? 59.213 37.660 -15.295 1.00 27.66 ? 1602 HOH A O 1 HETATM 8862 O O . HOH F 6 . ? 57.192 35.915 -14.245 1.00 29.28 ? 1603 HOH A O 1 HETATM 8863 O O . HOH F 6 . ? 58.434 34.831 -12.365 1.00 36.25 ? 1604 HOH A O 1 HETATM 8864 O O . HOH F 6 . ? 58.007 34.629 -5.830 1.00 29.98 ? 1605 HOH A O 1 HETATM 8865 O O . HOH F 6 . ? 56.113 38.714 1.531 1.00 47.39 ? 1606 HOH A O 1 HETATM 8866 O O . HOH F 6 . ? 58.079 42.412 1.594 1.00 26.56 ? 1607 HOH A O 1 HETATM 8867 O O . HOH F 6 . ? 58.809 46.318 -1.334 1.00 18.42 ? 1608 HOH A O 1 HETATM 8868 O O . HOH F 6 . ? 59.208 49.938 -0.529 1.00 14.55 ? 1609 HOH A O 1 HETATM 8869 O O . HOH F 6 . ? 58.691 52.591 -0.151 1.00 12.96 ? 1610 HOH A O 1 HETATM 8870 O O . HOH F 6 . ? 56.068 53.420 -0.634 1.00 7.29 ? 1611 HOH A O 1 HETATM 8871 O O . HOH F 6 . ? 56.286 55.769 -2.090 1.00 9.44 ? 1612 HOH A O 1 HETATM 8872 O O . HOH F 6 . ? 58.812 56.763 -1.361 1.00 11.98 ? 1613 HOH A O 1 HETATM 8873 O O . HOH F 6 . ? 58.851 58.138 1.046 1.00 21.98 ? 1614 HOH A O 1 HETATM 8874 O O . HOH F 6 . ? 56.413 58.623 1.428 1.00 27.78 ? 1615 HOH A O 1 HETATM 8875 O O . HOH F 6 . ? 56.909 61.009 1.625 1.00 16.65 ? 1616 HOH A O 1 HETATM 8876 O O . HOH F 6 . ? 55.202 59.016 3.904 1.00 14.42 ? 1617 HOH A O 1 HETATM 8877 O O . HOH F 6 . ? 57.465 58.571 5.587 1.00 23.13 ? 1618 HOH A O 1 HETATM 8878 O O . HOH F 6 . ? 57.557 62.387 7.873 1.00 27.50 ? 1619 HOH A O 1 HETATM 8879 O O . HOH F 6 . ? 56.348 66.955 5.246 1.00 30.39 ? 1620 HOH A O 1 HETATM 8880 O O . HOH F 6 . ? 59.279 68.186 2.495 1.00 22.01 ? 1621 HOH A O 1 HETATM 8881 O O . HOH F 6 . ? 60.450 73.313 -0.213 1.00 45.31 ? 1622 HOH A O 1 HETATM 8882 O O . HOH F 6 . ? 58.838 77.270 1.172 1.00 35.19 ? 1623 HOH A O 1 HETATM 8883 O O . HOH F 6 . ? 56.767 75.864 0.206 1.00 35.13 ? 1624 HOH A O 1 HETATM 8884 O O . HOH F 6 . ? 57.132 75.435 -2.880 1.00 26.50 ? 1625 HOH A O 1 HETATM 8885 O O . HOH F 6 . ? 59.090 76.854 -4.173 1.00 27.91 ? 1626 HOH A O 1 HETATM 8886 O O . HOH F 6 . ? 60.233 74.959 -4.562 1.00 35.92 ? 1627 HOH A O 1 HETATM 8887 O O . HOH F 6 . ? 59.458 76.526 -9.000 1.00 13.90 ? 1628 HOH A O 1 HETATM 8888 O O . HOH F 6 . ? 61.818 76.404 -10.501 1.00 16.52 ? 1629 HOH A O 1 HETATM 8889 O O . HOH F 6 . ? 61.254 77.502 -12.993 1.00 21.08 ? 1630 HOH A O 1 HETATM 8890 O O . HOH F 6 . ? 56.230 79.113 -14.939 1.00 30.23 ? 1631 HOH A O 1 HETATM 8891 O O . HOH F 6 . ? 49.977 79.879 -11.077 1.00 35.97 ? 1632 HOH A O 1 HETATM 8892 O O . HOH F 6 . ? 48.290 78.137 -9.623 1.00 26.17 ? 1633 HOH A O 1 HETATM 8893 O O . HOH F 6 . ? 45.682 79.239 -7.882 1.00 20.24 ? 1634 HOH A O 1 HETATM 8894 O O . HOH F 6 . ? 42.906 82.314 -9.868 1.00 23.63 ? 1635 HOH A O 1 HETATM 8895 O O . HOH F 6 . ? 40.353 82.870 -10.734 1.00 15.49 ? 1636 HOH A O 1 HETATM 8896 O O . HOH F 6 . ? 40.787 85.171 -12.110 1.00 24.25 ? 1637 HOH A O 1 HETATM 8897 O O . HOH F 6 . ? 41.255 77.626 -14.127 1.00 11.45 ? 1638 HOH A O 1 HETATM 8898 O O . HOH F 6 . ? 42.096 75.289 -16.013 1.00 13.06 ? 1639 HOH A O 1 HETATM 8899 O O . HOH F 6 . ? 46.334 67.710 -15.657 1.00 12.67 ? 1640 HOH A O 1 HETATM 8900 O O . HOH F 6 . ? 39.151 64.795 -14.772 1.00 10.41 ? 1641 HOH A O 1 HETATM 8901 O O . HOH F 6 . ? 39.157 62.870 -19.181 1.00 7.64 ? 1642 HOH A O 1 HETATM 8902 O O . HOH F 6 . ? 34.004 56.323 -26.385 1.00 9.23 ? 1643 HOH A O 1 HETATM 8903 O O . HOH F 6 . ? 31.975 58.618 -28.541 1.00 12.01 ? 1644 HOH A O 1 HETATM 8904 O O . HOH F 6 . ? 34.653 59.498 -35.043 1.00 16.54 ? 1645 HOH A O 1 HETATM 8905 O O . HOH F 6 . ? 33.516 57.108 -36.032 1.00 15.34 ? 1646 HOH A O 1 HETATM 8906 O O . HOH F 6 . ? 33.199 56.747 -38.876 1.00 31.56 ? 1647 HOH A O 1 HETATM 8907 O O . HOH F 6 . ? 30.933 58.176 -40.212 1.00 36.02 ? 1648 HOH A O 1 HETATM 8908 O O . HOH F 6 . ? 28.539 59.771 -39.241 1.00 32.14 ? 1649 HOH A O 1 HETATM 8909 O O . HOH F 6 . ? 28.993 62.249 -39.894 1.00 19.01 ? 1650 HOH A O 1 HETATM 8910 O O . HOH F 6 . ? 26.006 58.772 -39.137 1.00 37.96 ? 1651 HOH A O 1 HETATM 8911 O O . HOH F 6 . ? 17.185 57.080 -36.822 1.00 32.46 ? 1652 HOH A O 1 HETATM 8912 O O . HOH F 6 . ? 19.287 52.441 -31.551 1.00 33.17 ? 1653 HOH A O 1 HETATM 8913 O O . HOH F 6 . ? 19.487 52.589 -27.199 1.00 29.79 ? 1654 HOH A O 1 HETATM 8914 O O . HOH F 6 . ? 20.002 52.655 -24.401 1.00 15.99 ? 1655 HOH A O 1 HETATM 8915 O O . HOH F 6 . ? 22.706 53.089 -24.465 1.00 11.32 ? 1656 HOH A O 1 HETATM 8916 O O . HOH F 6 . ? 24.619 51.101 -24.149 1.00 12.02 ? 1657 HOH A O 1 HETATM 8917 O O . HOH F 6 . ? 23.760 48.437 -24.170 1.00 35.73 ? 1658 HOH A O 1 HETATM 8918 O O . HOH F 6 . ? 26.804 47.631 -23.839 1.00 27.43 ? 1659 HOH A O 1 HETATM 8919 O O . HOH F 6 . ? 27.386 48.488 -21.682 1.00 14.70 ? 1660 HOH A O 1 HETATM 8920 O O . HOH F 6 . ? 25.068 46.983 -20.903 1.00 22.25 ? 1661 HOH A O 1 HETATM 8921 O O . HOH F 6 . ? 28.560 49.722 -24.404 1.00 13.95 ? 1662 HOH A O 1 HETATM 8922 O O . HOH F 6 . ? 31.202 49.939 -24.076 1.00 10.01 ? 1663 HOH A O 1 HETATM 8923 O O . HOH F 6 . ? 35.526 45.221 -27.506 1.00 15.01 ? 1664 HOH A O 1 HETATM 8924 O O . HOH F 6 . ? 37.320 45.265 -25.486 1.00 18.46 ? 1665 HOH A O 1 HETATM 8925 O O . HOH F 6 . ? 36.012 42.070 -26.593 1.00 33.83 ? 1666 HOH A O 1 HETATM 8926 O O . HOH F 6 . ? 36.935 41.261 -24.593 1.00 24.03 ? 1667 HOH A O 1 HETATM 8927 O O . HOH F 6 . ? 38.606 42.161 -22.133 1.00 27.17 ? 1668 HOH A O 1 HETATM 8928 O O . HOH F 6 . ? 40.725 40.628 -21.556 1.00 23.64 ? 1669 HOH A O 1 HETATM 8929 O O . HOH F 6 . ? 43.153 40.596 -22.954 1.00 30.26 ? 1670 HOH A O 1 HETATM 8930 O O . HOH F 6 . ? 43.463 42.806 -24.791 1.00 31.61 ? 1671 HOH A O 1 HETATM 8931 O O . HOH F 6 . ? 41.403 44.597 -24.461 1.00 20.82 ? 1672 HOH A O 1 HETATM 8932 O O . HOH F 6 . ? 42.100 47.305 -24.590 1.00 12.80 ? 1673 HOH A O 1 HETATM 8933 O O . HOH F 6 . ? 42.509 47.190 -27.561 1.00 45.74 ? 1674 HOH A O 1 HETATM 8934 O O . HOH F 6 . ? 41.185 48.184 -29.401 1.00 46.13 ? 1675 HOH A O 1 HETATM 8935 O O . HOH F 6 . ? 39.182 48.855 -32.980 1.00 24.80 ? 1676 HOH A O 1 HETATM 8936 O O . HOH F 6 . ? 38.423 45.181 -33.850 1.00 17.95 ? 1677 HOH A O 1 HETATM 8937 O O . HOH F 6 . ? 38.547 51.388 -29.889 1.00 28.21 ? 1678 HOH A O 1 HETATM 8938 O O . HOH F 6 . ? 34.944 54.910 -34.630 1.00 38.70 ? 1679 HOH A O 1 HETATM 8939 O O . HOH F 6 . ? 31.787 51.242 -35.379 1.00 19.53 ? 1680 HOH A O 1 HETATM 8940 O O . HOH F 6 . ? 22.873 48.798 -36.243 1.00 38.65 ? 1681 HOH A O 1 HETATM 8941 O O . HOH F 6 . ? 21.658 47.042 -34.494 1.00 32.51 ? 1682 HOH A O 1 HETATM 8942 O O . HOH F 6 . ? 21.486 48.811 -39.004 1.00 34.29 ? 1683 HOH A O 1 HETATM 8943 O O . HOH F 6 . ? 23.631 55.553 -23.460 1.00 8.43 ? 1684 HOH A O 1 HETATM 8944 O O . HOH F 6 . ? 20.214 58.819 -22.033 1.00 8.77 ? 1685 HOH A O 1 HETATM 8945 O O . HOH F 6 . ? 13.483 57.791 -21.908 1.00 9.82 ? 1686 HOH A O 1 HETATM 8946 O O . HOH F 6 . ? 10.465 57.928 -21.030 1.00 31.23 ? 1687 HOH A O 1 HETATM 8947 O O . HOH F 6 . ? 9.848 60.251 -20.555 1.00 29.17 ? 1688 HOH A O 1 HETATM 8948 O O . HOH F 6 . ? 12.493 66.396 -9.638 1.00 18.78 ? 1689 HOH A O 1 HETATM 8949 O O . HOH F 6 . ? 13.970 68.319 -8.030 1.00 18.73 ? 1690 HOH A O 1 HETATM 8950 O O . HOH F 6 . ? 13.426 70.252 -9.593 1.00 31.50 ? 1691 HOH A O 1 HETATM 8951 O O . HOH F 6 . ? 13.005 66.846 -4.848 1.00 13.55 ? 1692 HOH A O 1 HETATM 8952 O O . HOH F 6 . ? 13.070 68.865 0.829 1.00 19.05 ? 1693 HOH A O 1 HETATM 8953 O O . HOH F 6 . ? 12.118 67.250 2.760 1.00 47.39 ? 1694 HOH A O 1 HETATM 8954 O O . HOH F 6 . ? 11.709 70.999 2.649 1.00 33.02 ? 1695 HOH A O 1 HETATM 8955 O O . HOH F 6 . ? 12.745 71.258 -0.540 1.00 27.40 ? 1696 HOH A O 1 HETATM 8956 O O . HOH F 6 . ? 16.712 74.685 -3.083 1.00 12.33 ? 1697 HOH A O 1 HETATM 8957 O O . HOH F 6 . ? 19.959 74.411 -6.864 1.00 10.92 ? 1698 HOH A O 1 HETATM 8958 O O . HOH F 6 . ? 24.505 70.577 -8.766 1.00 10.56 ? 1699 HOH A O 1 HETATM 8959 O O . HOH F 6 . ? 26.717 69.017 -9.281 1.00 7.29 ? 1700 HOH A O 1 HETATM 8960 O O . HOH F 6 . ? 32.569 64.681 -10.009 1.00 16.48 ? 1701 HOH A O 1 HETATM 8961 O O . HOH F 6 . ? 34.143 58.580 -8.772 1.00 7.27 ? 1702 HOH A O 1 HETATM 8962 O O . HOH F 6 . ? 30.086 58.490 -11.803 1.00 7.31 ? 1703 HOH A O 1 HETATM 8963 O O . HOH F 6 . ? 26.672 60.968 -3.350 1.00 8.95 ? 1704 HOH A O 1 HETATM 8964 O O . HOH F 6 . ? 32.477 60.149 -1.787 1.00 8.11 ? 1705 HOH A O 1 HETATM 8965 O O . HOH F 6 . ? 32.984 62.819 0.101 1.00 6.47 ? 1706 HOH A O 1 HETATM 8966 O O . HOH F 6 . ? 37.336 57.054 1.813 1.00 9.67 ? 1707 HOH A O 1 HETATM 8967 O O . HOH F 6 . ? 39.507 55.712 3.080 1.00 13.57 ? 1708 HOH A O 1 HETATM 8968 O O . HOH F 6 . ? 40.018 56.291 5.821 1.00 12.29 ? 1709 HOH A O 1 HETATM 8969 O O . HOH F 6 . ? 42.888 56.794 6.212 1.00 10.14 ? 1710 HOH A O 1 HETATM 8970 O O . HOH F 6 . ? 42.600 56.471 2.828 1.00 15.35 ? 1711 HOH A O 1 HETATM 8971 O O . HOH F 6 . ? 38.767 53.054 2.107 1.00 27.63 ? 1712 HOH A O 1 HETATM 8972 O O . HOH F 6 . ? 35.819 53.142 1.345 1.00 11.21 ? 1713 HOH A O 1 HETATM 8973 O O . HOH F 6 . ? 34.138 52.436 -0.942 1.00 7.73 ? 1714 HOH A O 1 HETATM 8974 O O . HOH F 6 . ? 36.621 51.694 3.824 1.00 11.74 ? 1715 HOH A O 1 HETATM 8975 O O . HOH F 6 . ? 30.684 57.275 4.635 1.00 15.11 ? 1716 HOH A O 1 HETATM 8976 O O . HOH F 6 . ? 27.429 59.281 8.652 1.00 21.70 ? 1717 HOH A O 1 HETATM 8977 O O . HOH F 6 . ? 26.901 61.409 10.522 1.00 26.64 ? 1718 HOH A O 1 HETATM 8978 O O . HOH F 6 . ? 28.603 63.548 10.711 1.00 17.54 ? 1719 HOH A O 1 HETATM 8979 O O . HOH F 6 . ? 29.233 65.603 12.463 1.00 18.06 ? 1720 HOH A O 1 HETATM 8980 O O . HOH F 6 . ? 27.768 67.497 11.665 1.00 33.24 ? 1721 HOH A O 1 HETATM 8981 O O . HOH F 6 . ? 28.765 69.669 12.756 1.00 27.78 ? 1722 HOH A O 1 HETATM 8982 O O . HOH F 6 . ? 29.692 72.262 12.302 1.00 16.58 ? 1723 HOH A O 1 HETATM 8983 O O . HOH F 6 . ? 31.867 71.188 13.652 1.00 23.67 ? 1724 HOH A O 1 HETATM 8984 O O . HOH F 6 . ? 34.607 70.518 13.174 1.00 12.57 ? 1725 HOH A O 1 HETATM 8985 O O . HOH F 6 . ? 34.237 67.815 12.513 1.00 9.75 ? 1726 HOH A O 1 HETATM 8986 O O . HOH F 6 . ? 30.949 68.351 14.138 1.00 19.89 ? 1727 HOH A O 1 HETATM 8987 O O . HOH F 6 . ? 29.154 67.099 15.713 1.00 26.09 ? 1728 HOH A O 1 HETATM 8988 O O . HOH F 6 . ? 28.454 64.701 14.825 1.00 20.15 ? 1729 HOH A O 1 HETATM 8989 O O . HOH F 6 . ? 26.357 63.765 17.043 1.00 15.28 ? 1730 HOH A O 1 HETATM 8990 O O . HOH F 6 . ? 25.488 66.164 17.481 1.00 23.19 ? 1731 HOH A O 1 HETATM 8991 O O . HOH F 6 . ? 26.320 66.709 19.896 1.00 24.14 ? 1732 HOH A O 1 HETATM 8992 O O . HOH F 6 . ? 28.648 65.158 19.720 1.00 13.68 ? 1733 HOH A O 1 HETATM 8993 O O . HOH F 6 . ? 29.873 67.196 18.378 1.00 19.82 ? 1734 HOH A O 1 HETATM 8994 O O . HOH F 6 . ? 31.952 65.614 19.088 1.00 11.85 ? 1735 HOH A O 1 HETATM 8995 O O . HOH F 6 . ? 33.089 67.039 21.335 1.00 18.29 ? 1736 HOH A O 1 HETATM 8996 O O . HOH F 6 . ? 32.605 69.562 22.124 1.00 27.18 ? 1737 HOH A O 1 HETATM 8997 O O . HOH F 6 . ? 32.702 69.308 24.564 1.00 22.69 ? 1738 HOH A O 1 HETATM 8998 O O . HOH F 6 . ? 36.024 68.604 24.445 1.00 19.45 ? 1739 HOH A O 1 HETATM 8999 O O . HOH F 6 . ? 36.588 66.752 25.683 1.00 24.99 ? 1740 HOH A O 1 HETATM 9000 O O . HOH F 6 . ? 35.754 68.040 20.642 1.00 29.47 ? 1741 HOH A O 1 HETATM 9001 O O . HOH F 6 . ? 38.208 73.717 18.248 1.00 26.13 ? 1742 HOH A O 1 HETATM 9002 O O . HOH F 6 . ? 46.120 74.352 22.494 1.00 27.12 ? 1743 HOH A O 1 HETATM 9003 O O . HOH F 6 . ? 46.320 68.443 26.523 1.00 31.33 ? 1744 HOH A O 1 HETATM 9004 O O . HOH F 6 . ? 47.778 66.011 27.026 1.00 34.32 ? 1745 HOH A O 1 HETATM 9005 O O . HOH F 6 . ? 50.711 61.882 26.521 1.00 17.93 ? 1746 HOH A O 1 HETATM 9006 O O . HOH F 6 . ? 51.916 60.319 28.244 1.00 28.10 ? 1747 HOH A O 1 HETATM 9007 O O . HOH F 6 . ? 51.971 58.026 29.207 1.00 38.08 ? 1748 HOH A O 1 HETATM 9008 O O . HOH F 6 . ? 45.186 58.261 32.355 1.00 30.16 ? 1749 HOH A O 1 HETATM 9009 O O . HOH F 6 . ? 43.668 56.778 33.765 1.00 24.67 ? 1750 HOH A O 1 HETATM 9010 O O . HOH F 6 . ? 42.683 53.383 35.763 1.00 21.57 ? 1751 HOH A O 1 HETATM 9011 O O . HOH F 6 . ? 39.832 52.719 36.303 1.00 29.09 ? 1752 HOH A O 1 HETATM 9012 O O . HOH F 6 . ? 39.320 49.868 36.555 1.00 35.57 ? 1753 HOH A O 1 HETATM 9013 O O . HOH F 6 . ? 41.743 50.608 33.817 1.00 30.93 ? 1754 HOH A O 1 HETATM 9014 O O . HOH F 6 . ? 48.339 50.931 35.167 1.00 23.21 ? 1755 HOH A O 1 HETATM 9015 O O . HOH F 6 . ? 49.891 50.202 36.902 1.00 28.59 ? 1756 HOH A O 1 HETATM 9016 O O . HOH F 6 . ? 47.558 53.602 35.945 1.00 33.23 ? 1757 HOH A O 1 HETATM 9017 O O . HOH F 6 . ? 49.474 50.790 32.695 1.00 27.20 ? 1758 HOH A O 1 HETATM 9018 O O . HOH F 6 . ? 53.832 49.847 29.547 1.00 36.04 ? 1759 HOH A O 1 HETATM 9019 O O . HOH F 6 . ? 51.821 63.923 24.615 1.00 22.60 ? 1760 HOH A O 1 HETATM 9020 O O . HOH F 6 . ? 42.516 66.979 29.481 1.00 25.91 ? 1761 HOH A O 1 HETATM 9021 O O . HOH F 6 . ? 39.783 66.954 31.395 1.00 29.03 ? 1762 HOH A O 1 HETATM 9022 O O . HOH F 6 . ? 42.066 61.379 33.468 1.00 38.72 ? 1763 HOH A O 1 HETATM 9023 O O . HOH F 6 . ? 37.892 62.228 35.488 1.00 34.28 ? 1764 HOH A O 1 HETATM 9024 O O . HOH F 6 . ? 35.519 61.993 34.218 1.00 28.89 ? 1765 HOH A O 1 HETATM 9025 O O . HOH F 6 . ? 30.908 61.771 35.607 1.00 31.90 ? 1766 HOH A O 1 HETATM 9026 O O . HOH F 6 . ? 30.061 59.334 35.224 1.00 24.91 ? 1767 HOH A O 1 HETATM 9027 O O . HOH F 6 . ? 31.448 57.455 37.524 1.00 29.34 ? 1768 HOH A O 1 HETATM 9028 O O . HOH F 6 . ? 28.303 55.348 40.134 1.00 26.69 ? 1769 HOH A O 1 HETATM 9029 O O . HOH F 6 . ? 25.764 57.563 40.488 1.00 31.69 ? 1770 HOH A O 1 HETATM 9030 O O . HOH F 6 . ? 23.866 57.466 38.751 1.00 31.12 ? 1771 HOH A O 1 HETATM 9031 O O . HOH F 6 . ? 21.594 55.373 40.166 1.00 24.45 ? 1772 HOH A O 1 HETATM 9032 O O . HOH F 6 . ? 17.626 53.455 35.074 1.00 18.87 ? 1773 HOH A O 1 HETATM 9033 O O . HOH F 6 . ? 18.643 48.864 37.609 1.00 12.67 ? 1774 HOH A O 1 HETATM 9034 O O . HOH F 6 . ? 20.908 47.545 39.072 1.00 14.07 ? 1775 HOH A O 1 HETATM 9035 O O . HOH F 6 . ? 18.686 46.483 40.352 1.00 23.99 ? 1776 HOH A O 1 HETATM 9036 O O . HOH F 6 . ? 20.113 41.440 34.925 1.00 40.21 ? 1777 HOH A O 1 HETATM 9037 O O . HOH F 6 . ? 20.012 43.373 33.849 1.00 22.14 ? 1778 HOH A O 1 HETATM 9038 O O . HOH F 6 . ? 16.807 41.846 32.075 1.00 30.53 ? 1779 HOH A O 1 HETATM 9039 O O . HOH F 6 . ? 15.778 39.882 33.907 1.00 35.98 ? 1780 HOH A O 1 HETATM 9040 O O . HOH F 6 . ? 21.154 35.462 34.603 1.00 34.93 ? 1781 HOH A O 1 HETATM 9041 O O . HOH F 6 . ? 24.317 34.572 35.782 1.00 27.81 ? 1782 HOH A O 1 HETATM 9042 O O . HOH F 6 . ? 27.760 34.833 32.239 1.00 32.01 ? 1783 HOH A O 1 HETATM 9043 O O . HOH F 6 . ? 26.911 35.073 29.543 1.00 22.37 ? 1784 HOH A O 1 HETATM 9044 O O . HOH F 6 . ? 25.870 32.747 28.699 1.00 28.41 ? 1785 HOH A O 1 HETATM 9045 O O . HOH F 6 . ? 22.312 31.240 29.516 1.00 27.81 ? 1786 HOH A O 1 HETATM 9046 O O . HOH F 6 . ? 21.420 29.251 27.945 1.00 30.10 ? 1787 HOH A O 1 HETATM 9047 O O . HOH F 6 . ? 18.467 32.082 25.737 1.00 28.80 ? 1788 HOH A O 1 HETATM 9048 O O . HOH F 6 . ? 19.720 35.530 25.539 1.00 24.45 ? 1789 HOH A O 1 HETATM 9049 O O . HOH F 6 . ? 19.095 36.456 22.299 1.00 26.24 ? 1790 HOH A O 1 HETATM 9050 O O . HOH F 6 . ? 18.532 37.597 19.776 1.00 23.23 ? 1791 HOH A O 1 HETATM 9051 O O . HOH F 6 . ? 19.525 39.257 17.524 1.00 16.25 ? 1792 HOH A O 1 HETATM 9052 O O . HOH F 6 . ? 21.426 38.101 15.712 1.00 21.26 ? 1793 HOH A O 1 HETATM 9053 O O . HOH F 6 . ? 23.206 36.948 13.433 1.00 25.14 ? 1794 HOH A O 1 HETATM 9054 O O . HOH F 6 . ? 21.958 34.630 12.642 1.00 37.90 ? 1795 HOH A O 1 HETATM 9055 O O . HOH F 6 . ? 25.149 33.335 13.269 1.00 30.11 ? 1796 HOH A O 1 HETATM 9056 O O . HOH F 6 . ? 24.084 34.372 15.606 1.00 23.54 ? 1797 HOH A O 1 HETATM 9057 O O . HOH F 6 . ? 20.985 30.276 17.740 1.00 33.80 ? 1798 HOH A O 1 HETATM 9058 O O . HOH F 6 . ? 16.185 33.977 15.609 1.00 33.18 ? 1799 HOH A O 1 HETATM 9059 O O . HOH F 6 . ? 16.393 36.502 16.777 1.00 28.52 ? 1800 HOH A O 1 HETATM 9060 O O . HOH F 6 . ? 17.647 35.372 13.375 1.00 35.21 ? 1801 HOH A O 1 HETATM 9061 O O . HOH F 6 . ? 20.331 37.927 12.231 1.00 21.99 ? 1802 HOH A O 1 HETATM 9062 O O . HOH F 6 . ? 24.869 39.989 14.282 1.00 14.94 ? 1803 HOH A O 1 HETATM 9063 O O . HOH F 6 . ? 27.093 41.394 13.344 1.00 12.88 ? 1804 HOH A O 1 HETATM 9064 O O . HOH F 6 . ? 28.171 43.932 13.244 1.00 9.23 ? 1805 HOH A O 1 HETATM 9065 O O . HOH F 6 . ? 27.104 46.400 13.724 1.00 16.67 ? 1806 HOH A O 1 HETATM 9066 O O . HOH F 6 . ? 28.041 48.951 12.307 1.00 14.30 ? 1807 HOH A O 1 HETATM 9067 O O . HOH F 6 . ? 26.381 51.650 13.117 1.00 22.37 ? 1808 HOH A O 1 HETATM 9068 O O . HOH F 6 . ? 25.363 53.698 11.255 1.00 12.39 ? 1809 HOH A O 1 HETATM 9069 O O . HOH F 6 . ? 19.208 55.277 11.488 1.00 10.12 ? 1810 HOH A O 1 HETATM 9070 O O . HOH F 6 . ? 18.179 55.017 14.085 1.00 11.35 ? 1811 HOH A O 1 HETATM 9071 O O . HOH F 6 . ? 19.975 54.822 16.106 1.00 10.23 ? 1812 HOH A O 1 HETATM 9072 O O . HOH F 6 . ? 16.624 57.161 12.931 1.00 11.93 ? 1813 HOH A O 1 HETATM 9073 O O . HOH F 6 . ? 16.905 56.342 10.276 1.00 11.80 ? 1814 HOH A O 1 HETATM 9074 O O . HOH F 6 . ? 19.181 53.593 8.182 1.00 9.24 ? 1815 HOH A O 1 HETATM 9075 O O . HOH F 6 . ? 17.437 52.815 6.312 1.00 9.81 ? 1816 HOH A O 1 HETATM 9076 O O . HOH F 6 . ? 19.951 56.075 7.152 1.00 10.20 ? 1817 HOH A O 1 HETATM 9077 O O . HOH F 6 . ? 21.597 57.159 5.066 1.00 10.32 ? 1818 HOH A O 1 HETATM 9078 O O . HOH F 6 . ? 23.790 58.121 6.313 1.00 10.05 ? 1819 HOH A O 1 HETATM 9079 O O . HOH F 6 . ? 24.495 61.532 9.017 1.00 11.94 ? 1820 HOH A O 1 HETATM 9080 O O . HOH F 6 . ? 23.382 63.806 7.924 1.00 16.97 ? 1821 HOH A O 1 HETATM 9081 O O . HOH F 6 . ? 25.990 64.516 8.497 1.00 17.00 ? 1822 HOH A O 1 HETATM 9082 O O . HOH F 6 . ? 26.319 67.106 9.393 1.00 17.86 ? 1823 HOH A O 1 HETATM 9083 O O . HOH F 6 . ? 23.322 66.307 9.806 1.00 29.73 ? 1824 HOH A O 1 HETATM 9084 O O . HOH F 6 . ? 20.580 68.155 8.556 1.00 29.09 ? 1825 HOH A O 1 HETATM 9085 O O . HOH F 6 . ? 20.402 65.446 7.674 1.00 22.34 ? 1826 HOH A O 1 HETATM 9086 O O . HOH F 6 . ? 18.393 70.014 4.209 1.00 13.14 ? 1827 HOH A O 1 HETATM 9087 O O . HOH F 6 . ? 17.261 70.693 6.427 1.00 41.89 ? 1828 HOH A O 1 HETATM 9088 O O . HOH F 6 . ? 15.425 73.710 5.429 1.00 30.58 ? 1829 HOH A O 1 HETATM 9089 O O . HOH F 6 . ? 17.656 74.514 3.867 1.00 22.17 ? 1830 HOH A O 1 HETATM 9090 O O . HOH F 6 . ? 18.940 76.628 4.669 1.00 27.78 ? 1831 HOH A O 1 HETATM 9091 O O . HOH F 6 . ? 21.291 79.966 5.292 1.00 25.07 ? 1832 HOH A O 1 HETATM 9092 O O . HOH F 6 . ? 22.100 76.895 8.651 1.00 28.95 ? 1833 HOH A O 1 HETATM 9093 O O . HOH F 6 . ? 25.311 74.090 8.697 1.00 17.79 ? 1834 HOH A O 1 HETATM 9094 O O . HOH F 6 . ? 25.946 72.851 5.595 1.00 10.68 ? 1835 HOH A O 1 HETATM 9095 O O . HOH F 6 . ? 26.368 75.048 2.117 1.00 18.64 ? 1836 HOH A O 1 HETATM 9096 O O . HOH F 6 . ? 21.209 78.542 -1.427 1.00 18.00 ? 1837 HOH A O 1 HETATM 9097 O O . HOH F 6 . ? 16.218 80.242 -1.199 1.00 36.88 ? 1838 HOH A O 1 HETATM 9098 O O . HOH F 6 . ? 16.405 82.297 -5.064 1.00 35.26 ? 1839 HOH A O 1 HETATM 9099 O O . HOH F 6 . ? 17.161 80.814 -7.652 1.00 21.62 ? 1840 HOH A O 1 HETATM 9100 O O . HOH F 6 . ? 20.960 84.074 -12.521 1.00 31.21 ? 1841 HOH A O 1 HETATM 9101 O O . HOH F 6 . ? 26.777 88.163 -4.052 1.00 37.00 ? 1842 HOH A O 1 HETATM 9102 O O . HOH F 6 . ? 24.708 83.794 2.642 1.00 30.94 ? 1843 HOH A O 1 HETATM 9103 O O . HOH F 6 . ? 29.578 75.818 10.947 1.00 26.19 ? 1844 HOH A O 1 HETATM 9104 O O . HOH F 6 . ? 29.863 74.995 22.208 1.00 28.07 ? 1845 HOH A O 1 HETATM 9105 O O . HOH F 6 . ? 28.846 72.484 22.320 1.00 27.43 ? 1846 HOH A O 1 HETATM 9106 O O . HOH F 6 . ? 25.366 71.081 22.253 1.00 25.30 ? 1847 HOH A O 1 HETATM 9107 O O . HOH F 6 . ? 24.865 68.337 21.800 1.00 16.88 ? 1848 HOH A O 1 HETATM 9108 O O . HOH F 6 . ? 22.538 68.225 20.353 1.00 20.63 ? 1849 HOH A O 1 HETATM 9109 O O . HOH F 6 . ? 22.739 66.925 17.926 1.00 33.70 ? 1850 HOH A O 1 HETATM 9110 O O . HOH F 6 . ? 22.890 64.108 18.244 1.00 23.15 ? 1851 HOH A O 1 HETATM 9111 O O . HOH F 6 . ? 22.542 62.596 16.076 1.00 17.35 ? 1852 HOH A O 1 HETATM 9112 O O . HOH F 6 . ? 27.900 60.995 19.526 1.00 9.12 ? 1853 HOH A O 1 HETATM 9113 O O . HOH F 6 . ? 30.096 55.799 17.253 1.00 7.54 ? 1854 HOH A O 1 HETATM 9114 O O . HOH F 6 . ? 27.543 53.363 20.112 1.00 13.16 ? 1855 HOH A O 1 HETATM 9115 O O . HOH F 6 . ? 26.818 51.600 22.649 1.00 18.99 ? 1856 HOH A O 1 HETATM 9116 O O . HOH F 6 . ? 22.922 56.212 30.862 1.00 13.24 ? 1857 HOH A O 1 HETATM 9117 O O . HOH F 6 . ? 18.124 59.593 31.749 1.00 28.11 ? 1858 HOH A O 1 HETATM 9118 O O . HOH F 6 . ? 17.370 61.800 33.281 1.00 30.57 ? 1859 HOH A O 1 HETATM 9119 O O . HOH F 6 . ? 19.657 62.764 34.797 1.00 33.06 ? 1860 HOH A O 1 HETATM 9120 O O . HOH F 6 . ? 22.009 62.878 33.731 1.00 24.70 ? 1861 HOH A O 1 HETATM 9121 O O . HOH F 6 . ? 22.108 65.560 32.422 1.00 29.54 ? 1862 HOH A O 1 HETATM 9122 O O . HOH F 6 . ? 22.301 66.793 28.926 1.00 23.08 ? 1863 HOH A O 1 HETATM 9123 O O . HOH F 6 . ? 20.337 65.645 27.175 1.00 21.28 ? 1864 HOH A O 1 HETATM 9124 O O . HOH F 6 . ? 17.788 65.990 27.870 1.00 19.57 ? 1865 HOH A O 1 HETATM 9125 O O . HOH F 6 . ? 17.841 66.512 30.624 1.00 26.06 ? 1866 HOH A O 1 HETATM 9126 O O . HOH F 6 . ? 16.907 68.529 26.672 1.00 26.65 ? 1867 HOH A O 1 HETATM 9127 O O . HOH F 6 . ? 17.862 68.513 24.202 1.00 35.56 ? 1868 HOH A O 1 HETATM 9128 O O . HOH F 6 . ? 15.813 68.747 21.867 1.00 27.86 ? 1869 HOH A O 1 HETATM 9129 O O . HOH F 6 . ? 20.503 68.422 22.220 1.00 21.08 ? 1870 HOH A O 1 HETATM 9130 O O . HOH F 6 . ? 14.144 69.301 27.071 1.00 23.32 ? 1871 HOH A O 1 HETATM 9131 O O . HOH F 6 . ? 14.037 63.216 30.069 1.00 29.55 ? 1872 HOH A O 1 HETATM 9132 O O . HOH F 6 . ? 15.939 57.654 31.587 1.00 31.25 ? 1873 HOH A O 1 HETATM 9133 O O . HOH F 6 . ? 14.474 55.439 27.215 1.00 28.33 ? 1874 HOH A O 1 HETATM 9134 O O . HOH F 6 . ? 13.143 52.795 25.894 1.00 34.60 ? 1875 HOH A O 1 HETATM 9135 O O . HOH F 6 . ? 13.990 50.663 24.244 1.00 17.92 ? 1876 HOH A O 1 HETATM 9136 O O . HOH F 6 . ? 16.322 49.238 24.032 1.00 11.89 ? 1877 HOH A O 1 HETATM 9137 O O . HOH F 6 . ? 14.272 47.352 26.587 1.00 36.91 ? 1878 HOH A O 1 HETATM 9138 O O . HOH F 6 . ? 13.919 44.863 27.084 1.00 29.42 ? 1879 HOH A O 1 HETATM 9139 O O . HOH F 6 . ? 17.130 43.563 27.418 1.00 22.78 ? 1880 HOH A O 1 HETATM 9140 O O . HOH F 6 . ? 17.791 41.870 25.296 1.00 22.35 ? 1881 HOH A O 1 HETATM 9141 O O . HOH F 6 . ? 18.493 39.472 26.161 1.00 32.33 ? 1882 HOH A O 1 HETATM 9142 O O . HOH F 6 . ? 25.884 37.577 29.429 1.00 14.96 ? 1883 HOH A O 1 HETATM 9143 O O . HOH F 6 . ? 29.788 36.563 29.265 1.00 21.68 ? 1884 HOH A O 1 HETATM 9144 O O . HOH F 6 . ? 36.730 37.247 25.239 1.00 35.45 ? 1885 HOH A O 1 HETATM 9145 O O . HOH F 6 . ? 37.029 40.167 26.572 1.00 28.30 ? 1886 HOH A O 1 HETATM 9146 O O . HOH F 6 . ? 34.910 43.519 28.874 1.00 12.86 ? 1887 HOH A O 1 HETATM 9147 O O . HOH F 6 . ? 35.644 45.115 30.903 1.00 16.77 ? 1888 HOH A O 1 HETATM 9148 O O . HOH F 6 . ? 37.356 46.903 29.821 1.00 19.81 ? 1889 HOH A O 1 HETATM 9149 O O . HOH F 6 . ? 36.937 45.610 27.603 1.00 13.68 ? 1890 HOH A O 1 HETATM 9150 O O . HOH F 6 . ? 39.616 45.401 25.991 1.00 30.11 ? 1891 HOH A O 1 HETATM 9151 O O . HOH F 6 . ? 38.869 42.971 22.879 1.00 24.15 ? 1892 HOH A O 1 HETATM 9152 O O . HOH F 6 . ? 39.479 39.584 20.108 1.00 29.66 ? 1893 HOH A O 1 HETATM 9153 O O . HOH F 6 . ? 39.089 38.925 17.329 1.00 16.10 ? 1894 HOH A O 1 HETATM 9154 O O . HOH F 6 . ? 41.764 39.191 16.701 1.00 27.39 ? 1895 HOH A O 1 HETATM 9155 O O . HOH F 6 . ? 38.217 36.300 17.781 1.00 34.71 ? 1896 HOH A O 1 HETATM 9156 O O . HOH F 6 . ? 34.102 34.362 16.244 1.00 20.87 ? 1897 HOH A O 1 HETATM 9157 O O . HOH F 6 . ? 31.826 33.613 17.046 1.00 27.87 ? 1898 HOH A O 1 HETATM 9158 O O . HOH F 6 . ? 29.421 31.534 22.051 1.00 34.41 ? 1899 HOH A O 1 HETATM 9159 O O . HOH F 6 . ? 29.651 30.000 24.526 1.00 38.19 ? 1900 HOH A O 1 HETATM 9160 O O . HOH F 6 . ? 20.710 31.849 31.878 1.00 41.41 ? 1901 HOH A O 1 HETATM 9161 O O . HOH F 6 . ? 11.302 33.350 22.702 1.00 35.89 ? 1902 HOH A O 1 HETATM 9162 O O . HOH F 6 . ? 11.381 41.342 19.623 1.00 25.06 ? 1903 HOH A O 1 HETATM 9163 O O . HOH F 6 . ? 12.218 43.356 20.160 1.00 37.15 ? 1904 HOH A O 1 HETATM 9164 O O . HOH F 6 . ? 10.963 46.805 21.563 1.00 29.31 ? 1905 HOH A O 1 HETATM 9165 O O . HOH F 6 . ? 12.361 45.305 23.583 1.00 28.65 ? 1906 HOH A O 1 HETATM 9166 O O . HOH F 6 . ? 11.321 46.960 17.854 1.00 19.67 ? 1907 HOH A O 1 HETATM 9167 O O . HOH F 6 . ? 12.286 49.584 17.709 1.00 17.04 ? 1908 HOH A O 1 HETATM 9168 O O . HOH F 6 . ? 14.107 49.920 19.724 1.00 13.28 ? 1909 HOH A O 1 HETATM 9169 O O . HOH F 6 . ? 13.222 51.598 21.693 1.00 15.70 ? 1910 HOH A O 1 HETATM 9170 O O . HOH F 6 . ? 10.575 51.661 21.356 1.00 24.21 ? 1911 HOH A O 1 HETATM 9171 O O . HOH F 6 . ? 10.048 50.851 18.845 1.00 22.82 ? 1912 HOH A O 1 HETATM 9172 O O . HOH F 6 . ? 9.161 52.509 16.835 1.00 16.93 ? 1913 HOH A O 1 HETATM 9173 O O . HOH F 6 . ? 7.296 54.548 17.260 1.00 31.22 ? 1914 HOH A O 1 HETATM 9174 O O . HOH F 6 . ? 11.628 51.633 14.303 1.00 12.99 ? 1915 HOH A O 1 HETATM 9175 O O . HOH F 6 . ? 13.829 49.109 15.416 1.00 12.91 ? 1916 HOH A O 1 HETATM 9176 O O . HOH F 6 . ? 8.216 48.490 19.387 1.00 35.84 ? 1917 HOH A O 1 HETATM 9177 O O . HOH F 6 . ? 5.965 46.753 15.968 1.00 30.98 ? 1918 HOH A O 1 HETATM 9178 O O . HOH F 6 . ? 8.486 44.691 12.858 1.00 28.37 ? 1919 HOH A O 1 HETATM 9179 O O . HOH F 6 . ? 7.861 48.210 11.934 1.00 22.38 ? 1920 HOH A O 1 HETATM 9180 O O . HOH F 6 . ? 7.376 50.961 12.423 1.00 35.83 ? 1921 HOH A O 1 HETATM 9181 O O . HOH F 6 . ? 6.871 51.692 9.280 1.00 41.64 ? 1922 HOH A O 1 HETATM 9182 O O . HOH F 6 . ? 8.888 50.468 8.034 1.00 26.15 ? 1923 HOH A O 1 HETATM 9183 O O . HOH F 6 . ? 8.251 49.778 5.751 1.00 32.59 ? 1924 HOH A O 1 HETATM 9184 O O . HOH F 6 . ? 11.217 53.208 6.811 1.00 14.60 ? 1925 HOH A O 1 HETATM 9185 O O . HOH F 6 . ? 5.215 57.619 6.893 1.00 29.80 ? 1926 HOH A O 1 HETATM 9186 O O . HOH F 6 . ? 13.136 62.944 11.896 1.00 24.51 ? 1927 HOH A O 1 HETATM 9187 O O . HOH F 6 . ? 13.705 62.531 14.616 1.00 23.43 ? 1928 HOH A O 1 HETATM 9188 O O . HOH F 6 . ? 15.374 60.440 15.429 1.00 13.32 ? 1929 HOH A O 1 HETATM 9189 O O . HOH F 6 . ? 13.856 58.330 16.275 1.00 13.38 ? 1930 HOH A O 1 HETATM 9190 O O . HOH F 6 . ? 13.818 57.823 18.945 1.00 16.55 ? 1931 HOH A O 1 HETATM 9191 O O . HOH F 6 . ? 11.408 58.470 19.920 1.00 27.01 ? 1932 HOH A O 1 HETATM 9192 O O . HOH F 6 . ? 10.371 57.311 21.824 1.00 45.72 ? 1933 HOH A O 1 HETATM 9193 O O . HOH F 6 . ? 12.003 55.482 22.302 1.00 29.72 ? 1934 HOH A O 1 HETATM 9194 O O . HOH F 6 . ? 11.782 62.317 22.703 1.00 34.02 ? 1935 HOH A O 1 HETATM 9195 O O . HOH F 6 . ? 17.996 60.747 24.324 1.00 14.38 ? 1936 HOH A O 1 HETATM 9196 O O . HOH F 6 . ? 11.383 61.780 16.118 1.00 40.95 ? 1937 HOH A O 1 HETATM 9197 O O . HOH F 6 . ? 19.044 72.478 2.927 1.00 15.73 ? 1938 HOH A O 1 HETATM 9198 O O . HOH F 6 . ? 19.347 67.399 -2.815 1.00 21.10 ? 1939 HOH A O 1 HETATM 9199 O O . HOH F 6 . ? 10.439 77.307 -5.391 1.00 29.16 ? 1940 HOH A O 1 HETATM 9200 O O . HOH F 6 . ? 13.987 88.226 -20.093 1.00 30.58 ? 1941 HOH A O 1 HETATM 9201 O O . HOH F 6 . ? 27.020 98.956 -26.062 1.00 36.60 ? 1942 HOH A O 1 HETATM 9202 O O . HOH F 6 . ? 31.697 96.518 -27.412 1.00 23.81 ? 1943 HOH A O 1 HETATM 9203 O O . HOH F 6 . ? 40.043 100.051 -32.066 1.00 34.18 ? 1944 HOH A O 1 HETATM 9204 O O . HOH F 6 . ? 46.262 99.934 -31.114 1.00 48.16 ? 1945 HOH A O 1 HETATM 9205 O O . HOH F 6 . ? 47.477 99.975 -33.269 1.00 33.87 ? 1946 HOH A O 1 HETATM 9206 O O . HOH F 6 . ? 48.555 97.884 -33.941 1.00 30.65 ? 1947 HOH A O 1 HETATM 9207 O O . HOH F 6 . ? 48.250 98.043 -28.689 1.00 26.01 ? 1948 HOH A O 1 HETATM 9208 O O . HOH F 6 . ? 48.271 89.183 -30.911 1.00 12.80 ? 1949 HOH A O 1 HETATM 9209 O O . HOH F 6 . ? 56.446 92.845 -29.926 1.00 23.99 ? 1950 HOH A O 1 HETATM 9210 O O . HOH F 6 . ? 45.973 94.783 -37.943 1.00 28.26 ? 1951 HOH A O 1 HETATM 9211 O O . HOH F 6 . ? 43.372 93.845 -37.853 1.00 19.36 ? 1952 HOH A O 1 HETATM 9212 O O . HOH F 6 . ? 41.300 94.777 -39.730 1.00 24.11 ? 1953 HOH A O 1 HETATM 9213 O O . HOH F 6 . ? 40.744 96.338 -37.596 1.00 25.79 ? 1954 HOH A O 1 HETATM 9214 O O . HOH F 6 . ? 43.130 98.025 -37.354 1.00 29.46 ? 1955 HOH A O 1 HETATM 9215 O O . HOH F 6 . ? 46.116 96.979 -43.933 1.00 21.64 ? 1956 HOH A O 1 HETATM 9216 O O . HOH F 6 . ? 39.562 95.961 -43.827 1.00 21.25 ? 1957 HOH A O 1 HETATM 9217 O O . HOH F 6 . ? 38.580 93.994 -42.372 1.00 22.67 ? 1958 HOH A O 1 HETATM 9218 O O . HOH F 6 . ? 42.065 87.705 -41.064 1.00 15.35 ? 1959 HOH A O 1 HETATM 9219 O O . HOH F 6 . ? 43.561 88.388 -38.783 1.00 13.79 ? 1960 HOH A O 1 HETATM 9220 O O . HOH F 6 . ? 38.936 86.612 -41.704 1.00 26.22 ? 1961 HOH A O 1 HETATM 9221 O O . HOH F 6 . ? 38.534 83.551 -39.995 1.00 23.83 ? 1962 HOH A O 1 HETATM 9222 O O . HOH F 6 . ? 34.063 86.655 -43.840 1.00 31.17 ? 1963 HOH A O 1 HETATM 9223 O O . HOH F 6 . ? 32.417 89.091 -43.209 1.00 24.40 ? 1964 HOH A O 1 HETATM 9224 O O . HOH F 6 . ? 34.068 73.714 -43.769 1.00 38.09 ? 1965 HOH A O 1 HETATM 9225 O O . HOH F 6 . ? 28.678 69.687 -39.551 1.00 18.24 ? 1966 HOH A O 1 HETATM 9226 O O . HOH F 6 . ? 24.662 71.756 -40.025 1.00 25.52 ? 1967 HOH A O 1 HETATM 9227 O O . HOH F 6 . ? 30.225 74.966 -29.337 1.00 10.82 ? 1968 HOH A O 1 HETATM 9228 O O . HOH F 6 . ? 32.297 77.687 -29.735 1.00 12.10 ? 1969 HOH A O 1 HETATM 9229 O O . HOH F 6 . ? 33.859 64.531 -32.364 1.00 12.80 ? 1970 HOH A O 1 HETATM 9230 O O . HOH F 6 . ? 35.982 63.544 -34.035 1.00 25.78 ? 1971 HOH A O 1 HETATM 9231 O O . HOH F 6 . ? 36.325 62.689 -38.528 1.00 33.64 ? 1972 HOH A O 1 HETATM 9232 O O . HOH F 6 . ? 36.464 63.308 -45.898 1.00 42.58 ? 1973 HOH A O 1 HETATM 9233 O O . HOH F 6 . ? 53.703 60.509 31.070 1.00 46.06 ? 1974 HOH A O 1 HETATM 9234 O O . HOH F 6 . ? 56.213 49.874 -30.074 1.00 41.72 ? 1975 HOH A O 1 HETATM 9235 O O . HOH F 6 . ? 59.999 52.730 -30.558 1.00 28.62 ? 1976 HOH A O 1 HETATM 9236 O O . HOH F 6 . ? 61.242 54.241 -29.034 1.00 20.86 ? 1977 HOH A O 1 HETATM 9237 O O . HOH F 6 . ? 58.681 53.670 -22.209 1.00 18.99 ? 1978 HOH A O 1 HETATM 9238 O O . HOH F 6 . ? 51.172 53.247 -23.942 1.00 9.40 ? 1979 HOH A O 1 HETATM 9239 O O . HOH F 6 . ? 53.565 64.787 -19.870 1.00 7.72 ? 1980 HOH A O 1 HETATM 9240 O O . HOH F 6 . ? 60.350 60.924 -18.158 1.00 8.86 ? 1981 HOH A O 1 HETATM 9241 O O . HOH F 6 . ? 55.519 59.334 -11.454 1.00 8.12 ? 1982 HOH A O 1 HETATM 9242 O O . HOH F 6 . ? 53.589 59.862 -9.375 1.00 10.96 ? 1983 HOH A O 1 HETATM 9243 O O . HOH F 6 . ? 50.799 59.896 -8.955 1.00 11.28 ? 1984 HOH A O 1 HETATM 9244 O O . HOH F 6 . ? 49.473 62.295 -8.627 1.00 10.91 ? 1985 HOH A O 1 HETATM 9245 O O . HOH F 6 . ? 49.903 59.516 -11.519 1.00 11.00 ? 1986 HOH A O 1 HETATM 9246 O O . HOH F 6 . ? 49.715 57.650 -7.543 1.00 10.16 ? 1987 HOH A O 1 HETATM 9247 O O . HOH F 6 . ? 51.365 56.672 -5.592 1.00 8.84 ? 1988 HOH A O 1 HETATM 9248 O O . HOH F 6 . ? 52.097 54.084 -4.826 1.00 7.97 ? 1989 HOH A O 1 HETATM 9249 O O . HOH F 6 . ? 52.675 58.891 -1.750 1.00 13.97 ? 1990 HOH A O 1 HETATM 9250 O O . HOH F 6 . ? 54.927 57.594 -0.407 1.00 14.51 ? 1991 HOH A O 1 HETATM 9251 O O . HOH F 6 . ? 60.461 54.786 -0.315 1.00 13.06 ? 1992 HOH A O 1 HETATM 9252 O O . HOH F 6 . ? 63.305 51.905 -0.506 1.00 26.91 ? 1993 HOH A O 1 HETATM 9253 O O . HOH F 6 . ? 59.430 52.143 2.615 1.00 30.19 ? 1994 HOH A O 1 HETATM 9254 O O . HOH F 6 . ? 58.430 52.732 4.700 1.00 28.63 ? 1995 HOH A O 1 HETATM 9255 O O . HOH F 6 . ? 59.441 48.955 2.259 1.00 29.83 ? 1996 HOH A O 1 HETATM 9256 O O . HOH F 6 . ? 52.068 50.550 6.372 1.00 10.10 ? 1997 HOH A O 1 HETATM 9257 O O . HOH F 6 . ? 44.339 46.063 10.079 1.00 15.06 ? 1998 HOH A O 1 HETATM 9258 O O . HOH F 6 . ? 42.924 48.058 11.328 1.00 13.92 ? 1999 HOH A O 1 HETATM 9259 O O . HOH F 6 . ? 41.542 43.258 8.073 1.00 16.03 ? 2000 HOH A O 1 HETATM 9260 O O . HOH F 6 . ? 40.007 39.344 9.166 1.00 20.96 ? 2001 HOH A O 1 HETATM 9261 O O . HOH F 6 . ? 40.659 36.286 8.589 1.00 27.94 ? 2002 HOH A O 1 HETATM 9262 O O . HOH F 6 . ? 39.930 35.425 11.378 1.00 22.26 ? 2003 HOH A O 1 HETATM 9263 O O . HOH F 6 . ? 37.248 33.662 5.874 1.00 41.12 ? 2004 HOH A O 1 HETATM 9264 O O . HOH F 6 . ? 34.719 36.470 3.411 1.00 30.18 ? 2005 HOH A O 1 HETATM 9265 O O . HOH F 6 . ? 37.135 37.571 2.935 1.00 33.00 ? 2006 HOH A O 1 HETATM 9266 O O . HOH F 6 . ? 38.162 40.081 1.788 1.00 10.75 ? 2007 HOH A O 1 HETATM 9267 O O . HOH F 6 . ? 36.637 44.941 -5.462 1.00 9.68 ? 2008 HOH A O 1 HETATM 9268 O O . HOH F 6 . ? 41.341 44.768 -6.829 1.00 12.82 ? 2009 HOH A O 1 HETATM 9269 O O . HOH F 6 . ? 43.475 41.855 -7.559 1.00 21.03 ? 2010 HOH A O 1 HETATM 9270 O O . HOH F 6 . ? 42.174 40.501 -9.704 1.00 31.50 ? 2011 HOH A O 1 HETATM 9271 O O . HOH F 6 . ? 42.421 39.436 -15.768 1.00 20.20 ? 2012 HOH A O 1 HETATM 9272 O O . HOH F 6 . ? 41.475 41.180 -17.618 1.00 16.50 ? 2013 HOH A O 1 HETATM 9273 O O . HOH F 6 . ? 47.145 41.337 -14.781 1.00 22.38 ? 2014 HOH A O 1 HETATM 9274 O O . HOH F 6 . ? 51.691 40.886 -13.159 1.00 27.37 ? 2015 HOH A O 1 HETATM 9275 O O . HOH F 6 . ? 50.946 44.193 -7.996 1.00 10.28 ? 2016 HOH A O 1 HETATM 9276 O O . HOH F 6 . ? 48.653 44.172 -6.085 1.00 17.14 ? 2017 HOH A O 1 HETATM 9277 O O . HOH F 6 . ? 47.928 43.942 -8.605 1.00 18.64 ? 2018 HOH A O 1 HETATM 9278 O O . HOH F 6 . ? 47.859 41.586 -5.353 1.00 27.40 ? 2019 HOH A O 1 HETATM 9279 O O . HOH F 6 . ? 48.363 39.239 -3.385 1.00 36.35 ? 2020 HOH A O 1 HETATM 9280 O O . HOH F 6 . ? 47.336 42.931 -2.333 1.00 14.45 ? 2021 HOH A O 1 HETATM 9281 O O . HOH F 6 . ? 46.384 43.160 9.769 1.00 33.89 ? 2022 HOH A O 1 HETATM 9282 O O . HOH F 6 . ? 39.313 57.364 14.884 1.00 8.37 ? 2023 HOH A O 1 HETATM 9283 O O . HOH F 6 . ? 41.173 58.986 13.559 1.00 9.29 ? 2024 HOH A O 1 HETATM 9284 O O . HOH F 6 . ? 37.753 59.056 11.126 1.00 9.37 ? 2025 HOH A O 1 HETATM 9285 O O . HOH F 6 . ? 36.858 57.757 13.461 1.00 8.70 ? 2026 HOH A O 1 HETATM 9286 O O . HOH F 6 . ? 38.692 62.360 8.449 1.00 11.21 ? 2027 HOH A O 1 HETATM 9287 O O . HOH F 6 . ? 40.247 62.786 6.171 1.00 7.85 ? 2028 HOH A O 1 HETATM 9288 O O . HOH F 6 . ? 49.296 68.263 6.708 1.00 26.78 ? 2029 HOH A O 1 HETATM 9289 O O . HOH F 6 . ? 49.833 67.458 4.239 1.00 16.80 ? 2030 HOH A O 1 HETATM 9290 O O . HOH F 6 . ? 51.937 68.913 4.241 1.00 34.01 ? 2031 HOH A O 1 HETATM 9291 O O . HOH F 6 . ? 52.294 70.950 5.933 1.00 32.15 ? 2032 HOH A O 1 HETATM 9292 O O . HOH F 6 . ? 52.667 72.992 4.275 1.00 37.16 ? 2033 HOH A O 1 HETATM 9293 O O . HOH F 6 . ? 50.432 72.422 9.208 1.00 21.25 ? 2034 HOH A O 1 HETATM 9294 O O . HOH F 6 . ? 51.222 66.535 8.548 1.00 23.71 ? 2035 HOH A O 1 HETATM 9295 O O . HOH F 6 . ? 43.485 73.148 5.825 1.00 10.27 ? 2036 HOH A O 1 HETATM 9296 O O . HOH F 6 . ? 45.951 70.990 0.050 1.00 14.73 ? 2037 HOH A O 1 HETATM 9297 O O . HOH F 6 . ? 37.814 73.402 -2.262 1.00 9.66 ? 2038 HOH A O 1 HETATM 9298 O O . HOH F 6 . ? 36.979 71.933 -4.569 1.00 7.26 ? 2039 HOH A O 1 HETATM 9299 O O . HOH F 6 . ? 36.541 72.711 0.263 1.00 8.29 ? 2040 HOH A O 1 HETATM 9300 O O . HOH F 6 . ? 33.272 78.665 -5.153 1.00 11.34 ? 2041 HOH A O 1 HETATM 9301 O O . HOH F 6 . ? 31.280 76.810 -6.334 1.00 10.37 ? 2042 HOH A O 1 HETATM 9302 O O . HOH F 6 . ? 41.946 63.504 -7.163 1.00 6.68 ? 2043 HOH A O 1 HETATM 9303 O O . HOH F 6 . ? 59.459 60.610 -6.210 1.00 12.94 ? 2044 HOH A O 1 HETATM 9304 O O . HOH F 6 . ? 60.972 59.664 -8.231 1.00 7.57 ? 2045 HOH A O 1 HETATM 9305 O O . HOH F 6 . ? 63.056 61.311 -7.583 1.00 8.86 ? 2046 HOH A O 1 HETATM 9306 O O . HOH F 6 . ? 63.015 61.051 -4.840 1.00 13.55 ? 2047 HOH A O 1 HETATM 9307 O O . HOH F 6 . ? 60.638 60.864 -3.572 1.00 11.96 ? 2048 HOH A O 1 HETATM 9308 O O . HOH F 6 . ? 60.450 62.210 -1.248 1.00 12.67 ? 2049 HOH A O 1 HETATM 9309 O O . HOH F 6 . ? 60.670 58.241 -2.785 1.00 10.76 ? 2050 HOH A O 1 HETATM 9310 O O . HOH F 6 . ? 64.784 59.247 -3.610 1.00 12.43 ? 2051 HOH A O 1 HETATM 9311 O O . HOH F 6 . ? 71.249 59.775 1.292 1.00 31.04 ? 2052 HOH A O 1 HETATM 9312 O O . HOH F 6 . ? 73.511 62.924 -0.700 1.00 34.28 ? 2053 HOH A O 1 HETATM 9313 O O . HOH F 6 . ? 74.146 52.113 1.524 1.00 32.14 ? 2054 HOH A O 1 HETATM 9314 O O . HOH F 6 . ? 72.340 50.779 2.029 1.00 35.96 ? 2055 HOH A O 1 HETATM 9315 O O . HOH F 6 . ? 70.839 49.427 0.015 1.00 20.67 ? 2056 HOH A O 1 HETATM 9316 O O . HOH F 6 . ? 71.928 46.826 -0.328 1.00 35.68 ? 2057 HOH A O 1 HETATM 9317 O O . HOH F 6 . ? 75.551 48.233 -5.656 1.00 40.21 ? 2058 HOH A O 1 HETATM 9318 O O . HOH F 6 . ? 10.263 50.496 -8.882 1.00 33.29 ? 2059 HOH A O 1 HETATM 9319 O O . HOH F 6 . ? 10.314 50.853 -11.253 1.00 46.98 ? 2060 HOH A O 1 HETATM 9320 O O . HOH F 6 . ? 73.229 51.402 -11.249 1.00 40.71 ? 2061 HOH A O 1 HETATM 9321 O O . HOH F 6 . ? 58.598 43.991 -28.018 1.00 29.93 ? 2062 HOH A O 1 HETATM 9322 O O . HOH F 6 . ? 36.304 36.129 -18.309 1.00 40.14 ? 2063 HOH A O 1 HETATM 9323 O O . HOH F 6 . ? 36.581 35.075 -15.935 1.00 30.48 ? 2064 HOH A O 1 HETATM 9324 O O . HOH F 6 . ? 35.520 38.747 -16.129 1.00 28.83 ? 2065 HOH A O 1 HETATM 9325 O O . HOH F 6 . ? 32.813 40.950 -18.000 1.00 22.73 ? 2066 HOH A O 1 HETATM 9326 O O . HOH F 6 . ? 25.574 36.196 -15.364 1.00 33.28 ? 2067 HOH A O 1 HETATM 9327 O O . HOH F 6 . ? 21.221 35.625 -5.143 1.00 30.77 ? 2068 HOH A O 1 HETATM 9328 O O . HOH F 6 . ? 21.826 36.850 0.146 1.00 19.29 ? 2069 HOH A O 1 HETATM 9329 O O . HOH F 6 . ? 24.763 34.186 0.415 1.00 40.44 ? 2070 HOH A O 1 HETATM 9330 O O . HOH F 6 . ? 24.673 33.125 6.660 1.00 20.55 ? 2071 HOH A O 1 HETATM 9331 O O . HOH F 6 . ? 24.375 33.113 9.585 1.00 24.95 ? 2072 HOH A O 1 HETATM 9332 O O . HOH F 6 . ? 26.115 40.087 7.993 1.00 10.32 ? 2073 HOH A O 1 HETATM 9333 O O . HOH F 6 . ? 25.716 39.779 5.277 1.00 10.36 ? 2074 HOH A O 1 HETATM 9334 O O . HOH F 6 . ? 23.880 41.977 6.943 1.00 9.67 ? 2075 HOH A O 1 HETATM 9335 O O . HOH F 6 . ? 27.995 39.644 11.285 1.00 10.73 ? 2076 HOH A O 1 HETATM 9336 O O . HOH F 6 . ? 31.025 33.580 2.826 1.00 20.40 ? 2077 HOH A O 1 HETATM 9337 O O . HOH F 6 . ? 30.963 29.787 5.629 1.00 33.02 ? 2078 HOH A O 1 HETATM 9338 O O . HOH F 6 . ? 36.691 29.114 12.999 1.00 29.54 ? 2079 HOH A O 1 HETATM 9339 O O . HOH F 6 . ? 18.248 36.682 5.806 1.00 29.70 ? 2080 HOH A O 1 HETATM 9340 O O . HOH F 6 . ? 17.097 41.659 9.261 1.00 32.09 ? 2081 HOH A O 1 HETATM 9341 O O . HOH F 6 . ? 12.720 42.507 12.449 1.00 17.94 ? 2082 HOH A O 1 HETATM 9342 O O . HOH F 6 . ? 12.323 46.721 30.557 1.00 29.62 ? 2083 HOH A O 1 HETATM 9343 O O . HOH F 6 . ? 14.362 47.155 32.511 1.00 20.14 ? 2084 HOH A O 1 HETATM 9344 O O . HOH F 6 . ? 27.713 49.491 38.497 1.00 22.23 ? 2085 HOH A O 1 HETATM 9345 O O . HOH F 6 . ? 28.791 47.076 37.217 1.00 17.25 ? 2086 HOH A O 1 HETATM 9346 O O . HOH F 6 . ? 31.276 47.379 38.093 1.00 32.42 ? 2087 HOH A O 1 HETATM 9347 O O . HOH F 6 . ? 34.110 47.862 36.219 1.00 36.08 ? 2088 HOH A O 1 HETATM 9348 O O . HOH F 6 . ? 34.432 45.735 33.366 1.00 17.26 ? 2089 HOH A O 1 HETATM 9349 O O . HOH F 6 . ? 27.815 44.419 38.271 1.00 30.19 ? 2090 HOH A O 1 HETATM 9350 O O . HOH F 6 . ? 29.908 51.287 39.867 1.00 45.70 ? 2091 HOH A O 1 HETATM 9351 O O . HOH F 6 . ? 27.389 52.234 42.562 1.00 26.28 ? 2092 HOH A O 1 HETATM 9352 O O . HOH F 6 . ? 26.620 50.932 45.335 1.00 32.49 ? 2093 HOH A O 1 HETATM 9353 O O . HOH F 6 . ? 26.964 47.547 45.712 1.00 42.15 ? 2094 HOH A O 1 HETATM 9354 O O . HOH F 6 . ? 28.963 47.598 47.157 1.00 49.54 ? 2095 HOH A O 1 HETATM 9355 O O . HOH F 6 . ? 24.008 61.031 36.074 1.00 25.47 ? 2096 HOH A O 1 HETATM 9356 O O . HOH F 6 . ? 29.483 65.581 32.578 1.00 27.97 ? 2097 HOH A O 1 HETATM 9357 O O . HOH F 6 . ? 28.818 64.388 30.177 1.00 17.53 ? 2098 HOH A O 1 HETATM 9358 O O . HOH F 6 . ? 27.740 67.549 28.230 1.00 17.14 ? 2099 HOH A O 1 HETATM 9359 O O . HOH F 6 . ? 61.396 92.413 -33.930 1.00 31.00 ? 2100 HOH A O 1 HETATM 9360 O O . HOH F 6 . ? 63.787 92.251 -34.394 1.00 22.68 ? 2101 HOH A O 1 HETATM 9361 O O . HOH F 6 . ? 33.601 60.237 23.285 1.00 11.45 ? 2102 HOH A O 1 HETATM 9362 O O . HOH F 6 . ? 51.199 79.403 -1.767 1.00 24.75 ? 2103 HOH A O 1 HETATM 9363 O O . HOH F 6 . ? 64.219 77.002 0.401 1.00 41.73 ? 2104 HOH A O 1 HETATM 9364 O O . HOH F 6 . ? 64.638 78.668 -1.558 1.00 24.30 ? 2105 HOH A O 1 HETATM 9365 O O . HOH F 6 . ? 65.381 77.443 2.912 1.00 35.07 ? 2106 HOH A O 1 HETATM 9366 O O . HOH F 6 . ? 54.876 81.000 -23.641 1.00 13.69 ? 2107 HOH A O 1 HETATM 9367 O O . HOH F 6 . ? 70.008 82.976 -29.948 1.00 20.96 ? 2108 HOH A O 1 HETATM 9368 O O . HOH F 6 . ? 72.254 95.652 -31.503 1.00 25.81 ? 2109 HOH A O 1 HETATM 9369 O O . HOH F 6 . ? 70.384 95.518 -35.281 1.00 40.23 ? 2110 HOH A O 1 HETATM 9370 O O . HOH F 6 . ? 62.086 81.629 -44.469 1.00 34.88 ? 2111 HOH A O 1 HETATM 9371 O O . HOH F 6 . ? 36.381 92.106 -17.688 1.00 34.18 ? 2112 HOH A O 1 HETATM 9372 O O . HOH F 6 . ? 29.552 102.088 -16.476 1.00 30.53 ? 2113 HOH A O 1 HETATM 9373 O O . HOH F 6 . ? 28.078 102.409 -19.169 1.00 24.21 ? 2114 HOH A O 1 HETATM 9374 O O . HOH F 6 . ? 19.808 46.783 -14.405 1.00 18.79 ? 2115 HOH A O 1 HETATM 9375 O O . HOH F 6 . ? 17.320 45.551 -14.170 1.00 37.11 ? 2116 HOH A O 1 HETATM 9376 O O . HOH F 6 . ? 15.870 44.885 -11.770 1.00 37.11 ? 2117 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 ? ? ? A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ASP 204 204 204 ASP ASP A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASP 341 341 341 ASP ASP A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 1046 1 NAG NAG A . C 3 ZN 1 1047 1 ZN ZN A . D 4 SWA 1 1048 1 SWA SWA A . E 5 MRD 1 1049 1 MRD MRD A . F 6 HOH 1 1050 1 HOH HOH A . F 6 HOH 2 1051 2 HOH HOH A . F 6 HOH 3 1052 3 HOH HOH A . F 6 HOH 4 1053 4 HOH HOH A . F 6 HOH 5 1054 5 HOH HOH A . F 6 HOH 6 1055 6 HOH HOH A . F 6 HOH 7 1056 7 HOH HOH A . F 6 HOH 8 1057 8 HOH HOH A . F 6 HOH 9 1058 9 HOH HOH A . F 6 HOH 10 1059 10 HOH HOH A . F 6 HOH 11 1060 11 HOH HOH A . F 6 HOH 12 1061 12 HOH HOH A . F 6 HOH 13 1062 13 HOH HOH A . F 6 HOH 14 1063 14 HOH HOH A . F 6 HOH 15 1064 15 HOH HOH A . F 6 HOH 16 1065 16 HOH HOH A . F 6 HOH 17 1066 17 HOH HOH A . F 6 HOH 18 1067 18 HOH HOH A . F 6 HOH 19 1068 19 HOH HOH A . F 6 HOH 20 1069 20 HOH HOH A . F 6 HOH 21 1070 21 HOH HOH A . F 6 HOH 22 1071 22 HOH HOH A . F 6 HOH 23 1072 23 HOH HOH A . F 6 HOH 24 1073 24 HOH HOH A . F 6 HOH 25 1074 25 HOH HOH A . F 6 HOH 26 1075 26 HOH HOH A . F 6 HOH 27 1076 27 HOH HOH A . F 6 HOH 28 1077 28 HOH HOH A . F 6 HOH 29 1078 29 HOH HOH A . F 6 HOH 30 1079 30 HOH HOH A . F 6 HOH 31 1080 31 HOH HOH A . F 6 HOH 32 1081 32 HOH HOH A . F 6 HOH 33 1082 33 HOH HOH A . F 6 HOH 34 1083 34 HOH HOH A . F 6 HOH 35 1084 35 HOH HOH A . F 6 HOH 36 1085 36 HOH HOH A . F 6 HOH 37 1086 37 HOH HOH A . F 6 HOH 38 1087 38 HOH HOH A . F 6 HOH 39 1088 39 HOH HOH A . F 6 HOH 40 1089 40 HOH HOH A . F 6 HOH 41 1090 41 HOH HOH A . F 6 HOH 42 1091 42 HOH HOH A . F 6 HOH 43 1092 43 HOH HOH A . F 6 HOH 44 1093 44 HOH HOH A . F 6 HOH 45 1094 45 HOH HOH A . F 6 HOH 46 1095 46 HOH HOH A . F 6 HOH 47 1096 47 HOH HOH A . F 6 HOH 48 1097 48 HOH HOH A . F 6 HOH 49 1098 49 HOH HOH A . F 6 HOH 50 1099 50 HOH HOH A . F 6 HOH 51 1100 51 HOH HOH A . F 6 HOH 52 1101 52 HOH HOH A . F 6 HOH 53 1102 53 HOH HOH A . F 6 HOH 54 1103 54 HOH HOH A . F 6 HOH 55 1104 55 HOH HOH A . F 6 HOH 56 1105 56 HOH HOH A . F 6 HOH 57 1106 57 HOH HOH A . F 6 HOH 58 1107 58 HOH HOH A . F 6 HOH 59 1108 59 HOH HOH A . F 6 HOH 60 1109 60 HOH HOH A . F 6 HOH 61 1110 61 HOH HOH A . F 6 HOH 62 1111 62 HOH HOH A . F 6 HOH 63 1112 63 HOH HOH A . F 6 HOH 64 1113 64 HOH HOH A . F 6 HOH 65 1114 65 HOH HOH A . F 6 HOH 66 1115 66 HOH HOH A . F 6 HOH 67 1116 67 HOH HOH A . F 6 HOH 68 1117 68 HOH HOH A . F 6 HOH 69 1118 69 HOH HOH A . F 6 HOH 70 1119 70 HOH HOH A . F 6 HOH 71 1120 71 HOH HOH A . F 6 HOH 72 1121 72 HOH HOH A . F 6 HOH 73 1122 73 HOH HOH A . F 6 HOH 74 1123 74 HOH HOH A . F 6 HOH 75 1124 75 HOH HOH A . F 6 HOH 76 1125 76 HOH HOH A . F 6 HOH 77 1126 77 HOH HOH A . F 6 HOH 78 1127 78 HOH HOH A . F 6 HOH 79 1128 79 HOH HOH A . F 6 HOH 80 1129 80 HOH HOH A . F 6 HOH 81 1130 81 HOH HOH A . F 6 HOH 82 1131 82 HOH HOH A . F 6 HOH 83 1132 83 HOH HOH A . F 6 HOH 84 1133 84 HOH HOH A . F 6 HOH 85 1134 85 HOH HOH A . F 6 HOH 86 1135 86 HOH HOH A . F 6 HOH 87 1136 87 HOH HOH A . F 6 HOH 88 1137 88 HOH HOH A . F 6 HOH 89 1138 89 HOH HOH A . F 6 HOH 90 1139 90 HOH HOH A . F 6 HOH 91 1140 91 HOH HOH A . F 6 HOH 92 1141 92 HOH HOH A . F 6 HOH 93 1142 93 HOH HOH A . F 6 HOH 94 1143 94 HOH HOH A . F 6 HOH 95 1144 95 HOH HOH A . F 6 HOH 96 1145 96 HOH HOH A . F 6 HOH 97 1146 97 HOH HOH A . F 6 HOH 98 1147 98 HOH HOH A . F 6 HOH 99 1148 99 HOH HOH A . F 6 HOH 100 1149 100 HOH HOH A . F 6 HOH 101 1150 101 HOH HOH A . F 6 HOH 102 1151 102 HOH HOH A . F 6 HOH 103 1152 103 HOH HOH A . F 6 HOH 104 1153 104 HOH HOH A . F 6 HOH 105 1154 105 HOH HOH A . F 6 HOH 106 1155 106 HOH HOH A . F 6 HOH 107 1156 107 HOH HOH A . F 6 HOH 108 1157 108 HOH HOH A . F 6 HOH 109 1158 109 HOH HOH A . F 6 HOH 110 1159 110 HOH HOH A . F 6 HOH 111 1160 111 HOH HOH A . F 6 HOH 112 1161 112 HOH HOH A . F 6 HOH 113 1162 113 HOH HOH A . F 6 HOH 114 1163 114 HOH HOH A . F 6 HOH 115 1164 115 HOH HOH A . F 6 HOH 116 1165 116 HOH HOH A . F 6 HOH 117 1166 117 HOH HOH A . F 6 HOH 118 1167 118 HOH HOH A . F 6 HOH 119 1168 119 HOH HOH A . F 6 HOH 120 1169 120 HOH HOH A . F 6 HOH 121 1170 121 HOH HOH A . F 6 HOH 122 1171 122 HOH HOH A . F 6 HOH 123 1172 123 HOH HOH A . F 6 HOH 124 1173 124 HOH HOH A . F 6 HOH 125 1174 125 HOH HOH A . F 6 HOH 126 1175 126 HOH HOH A . F 6 HOH 127 1176 127 HOH HOH A . F 6 HOH 128 1177 128 HOH HOH A . F 6 HOH 129 1178 129 HOH HOH A . F 6 HOH 130 1179 130 HOH HOH A . F 6 HOH 131 1180 131 HOH HOH A . F 6 HOH 132 1181 132 HOH HOH A . F 6 HOH 133 1182 133 HOH HOH A . F 6 HOH 134 1183 134 HOH HOH A . F 6 HOH 135 1184 135 HOH HOH A . F 6 HOH 136 1185 136 HOH HOH A . F 6 HOH 137 1186 137 HOH HOH A . F 6 HOH 138 1187 138 HOH HOH A . F 6 HOH 139 1188 139 HOH HOH A . F 6 HOH 140 1189 140 HOH HOH A . F 6 HOH 141 1190 141 HOH HOH A . F 6 HOH 142 1191 142 HOH HOH A . F 6 HOH 143 1192 143 HOH HOH A . F 6 HOH 144 1193 144 HOH HOH A . F 6 HOH 145 1194 145 HOH HOH A . F 6 HOH 146 1195 146 HOH HOH A . F 6 HOH 147 1196 147 HOH HOH A . F 6 HOH 148 1197 148 HOH HOH A . F 6 HOH 149 1198 149 HOH HOH A . F 6 HOH 150 1199 150 HOH HOH A . F 6 HOH 151 1200 151 HOH HOH A . F 6 HOH 152 1201 152 HOH HOH A . F 6 HOH 153 1202 153 HOH HOH A . F 6 HOH 154 1203 154 HOH HOH A . F 6 HOH 155 1204 155 HOH HOH A . F 6 HOH 156 1205 156 HOH HOH A . F 6 HOH 157 1206 157 HOH HOH A . F 6 HOH 158 1207 158 HOH HOH A . F 6 HOH 159 1208 159 HOH HOH A . F 6 HOH 160 1209 160 HOH HOH A . F 6 HOH 161 1210 161 HOH HOH A . F 6 HOH 162 1211 162 HOH HOH A . F 6 HOH 163 1212 163 HOH HOH A . F 6 HOH 164 1213 164 HOH HOH A . F 6 HOH 165 1214 165 HOH HOH A . F 6 HOH 166 1215 166 HOH HOH A . F 6 HOH 167 1216 167 HOH HOH A . F 6 HOH 168 1217 168 HOH HOH A . F 6 HOH 169 1218 169 HOH HOH A . F 6 HOH 170 1219 170 HOH HOH A . F 6 HOH 171 1220 171 HOH HOH A . F 6 HOH 172 1221 172 HOH HOH A . F 6 HOH 173 1222 173 HOH HOH A . F 6 HOH 174 1223 174 HOH HOH A . F 6 HOH 175 1224 175 HOH HOH A . F 6 HOH 176 1225 176 HOH HOH A . F 6 HOH 177 1226 177 HOH HOH A . F 6 HOH 178 1227 178 HOH HOH A . F 6 HOH 179 1228 179 HOH HOH A . F 6 HOH 180 1229 180 HOH HOH A . F 6 HOH 181 1230 181 HOH HOH A . F 6 HOH 182 1231 182 HOH HOH A . F 6 HOH 183 1232 183 HOH HOH A . F 6 HOH 184 1233 184 HOH HOH A . F 6 HOH 185 1234 185 HOH HOH A . F 6 HOH 186 1235 186 HOH HOH A . F 6 HOH 187 1236 187 HOH HOH A . F 6 HOH 188 1237 188 HOH HOH A . F 6 HOH 189 1238 189 HOH HOH A . F 6 HOH 190 1239 190 HOH HOH A . F 6 HOH 191 1240 191 HOH HOH A . F 6 HOH 192 1241 192 HOH HOH A . F 6 HOH 193 1242 193 HOH HOH A . F 6 HOH 194 1243 194 HOH HOH A . F 6 HOH 195 1244 195 HOH HOH A . F 6 HOH 196 1245 196 HOH HOH A . F 6 HOH 197 1246 197 HOH HOH A . F 6 HOH 198 1247 198 HOH HOH A . F 6 HOH 199 1248 199 HOH HOH A . F 6 HOH 200 1249 200 HOH HOH A . F 6 HOH 201 1250 201 HOH HOH A . F 6 HOH 202 1251 202 HOH HOH A . F 6 HOH 203 1252 203 HOH HOH A . F 6 HOH 204 1253 204 HOH HOH A . F 6 HOH 205 1254 205 HOH HOH A . F 6 HOH 206 1255 206 HOH HOH A . F 6 HOH 207 1256 207 HOH HOH A . F 6 HOH 208 1257 208 HOH HOH A . F 6 HOH 209 1258 209 HOH HOH A . F 6 HOH 210 1259 210 HOH HOH A . F 6 HOH 211 1260 211 HOH HOH A . F 6 HOH 212 1261 212 HOH HOH A . F 6 HOH 213 1262 213 HOH HOH A . F 6 HOH 214 1263 214 HOH HOH A . F 6 HOH 215 1264 215 HOH HOH A . F 6 HOH 216 1265 216 HOH HOH A . F 6 HOH 217 1266 217 HOH HOH A . F 6 HOH 218 1267 218 HOH HOH A . F 6 HOH 219 1268 219 HOH HOH A . F 6 HOH 220 1269 220 HOH HOH A . F 6 HOH 221 1270 221 HOH HOH A . F 6 HOH 222 1271 222 HOH HOH A . F 6 HOH 223 1272 223 HOH HOH A . F 6 HOH 224 1273 224 HOH HOH A . F 6 HOH 225 1274 225 HOH HOH A . F 6 HOH 226 1275 226 HOH HOH A . F 6 HOH 227 1276 227 HOH HOH A . F 6 HOH 228 1277 228 HOH HOH A . F 6 HOH 229 1278 229 HOH HOH A . F 6 HOH 230 1279 230 HOH HOH A . F 6 HOH 231 1280 231 HOH HOH A . F 6 HOH 232 1281 232 HOH HOH A . F 6 HOH 233 1282 233 HOH HOH A . F 6 HOH 234 1283 234 HOH HOH A . F 6 HOH 235 1284 235 HOH HOH A . F 6 HOH 236 1285 236 HOH HOH A . F 6 HOH 237 1286 237 HOH HOH A . F 6 HOH 238 1287 238 HOH HOH A . F 6 HOH 239 1288 239 HOH HOH A . F 6 HOH 240 1289 240 HOH HOH A . F 6 HOH 241 1290 241 HOH HOH A . F 6 HOH 242 1291 242 HOH HOH A . F 6 HOH 243 1292 243 HOH HOH A . F 6 HOH 244 1293 244 HOH HOH A . F 6 HOH 245 1294 245 HOH HOH A . F 6 HOH 246 1295 246 HOH HOH A . F 6 HOH 247 1296 247 HOH HOH A . F 6 HOH 248 1297 248 HOH HOH A . F 6 HOH 249 1298 249 HOH HOH A . F 6 HOH 250 1299 250 HOH HOH A . F 6 HOH 251 1300 251 HOH HOH A . F 6 HOH 252 1301 252 HOH HOH A . F 6 HOH 253 1302 253 HOH HOH A . F 6 HOH 254 1303 254 HOH HOH A . F 6 HOH 255 1304 255 HOH HOH A . F 6 HOH 256 1305 256 HOH HOH A . F 6 HOH 257 1306 257 HOH HOH A . F 6 HOH 258 1307 258 HOH HOH A . F 6 HOH 259 1308 259 HOH HOH A . F 6 HOH 260 1309 260 HOH HOH A . F 6 HOH 261 1310 261 HOH HOH A . F 6 HOH 262 1311 262 HOH HOH A . F 6 HOH 263 1312 263 HOH HOH A . F 6 HOH 264 1313 264 HOH HOH A . F 6 HOH 265 1314 265 HOH HOH A . F 6 HOH 266 1315 266 HOH HOH A . F 6 HOH 267 1316 267 HOH HOH A . F 6 HOH 268 1317 268 HOH HOH A . F 6 HOH 269 1318 269 HOH HOH A . F 6 HOH 270 1319 270 HOH HOH A . F 6 HOH 271 1320 271 HOH HOH A . F 6 HOH 272 1321 272 HOH HOH A . F 6 HOH 273 1322 273 HOH HOH A . F 6 HOH 274 1323 274 HOH HOH A . F 6 HOH 275 1324 275 HOH HOH A . F 6 HOH 276 1325 276 HOH HOH A . F 6 HOH 277 1326 277 HOH HOH A . F 6 HOH 278 1327 278 HOH HOH A . F 6 HOH 279 1328 279 HOH HOH A . F 6 HOH 280 1329 280 HOH HOH A . F 6 HOH 281 1330 281 HOH HOH A . F 6 HOH 282 1331 282 HOH HOH A . F 6 HOH 283 1332 283 HOH HOH A . F 6 HOH 284 1333 284 HOH HOH A . F 6 HOH 285 1334 285 HOH HOH A . F 6 HOH 286 1335 286 HOH HOH A . F 6 HOH 287 1336 287 HOH HOH A . F 6 HOH 288 1337 288 HOH HOH A . F 6 HOH 289 1338 289 HOH HOH A . F 6 HOH 290 1339 290 HOH HOH A . F 6 HOH 291 1340 291 HOH HOH A . F 6 HOH 292 1341 292 HOH HOH A . F 6 HOH 293 1342 293 HOH HOH A . F 6 HOH 294 1343 294 HOH HOH A . F 6 HOH 295 1344 295 HOH HOH A . F 6 HOH 296 1345 296 HOH HOH A . F 6 HOH 297 1346 297 HOH HOH A . F 6 HOH 298 1347 298 HOH HOH A . F 6 HOH 299 1348 299 HOH HOH A . F 6 HOH 300 1349 300 HOH HOH A . F 6 HOH 301 1350 301 HOH HOH A . F 6 HOH 302 1351 302 HOH HOH A . F 6 HOH 303 1352 303 HOH HOH A . F 6 HOH 304 1353 304 HOH HOH A . F 6 HOH 305 1354 305 HOH HOH A . F 6 HOH 306 1355 306 HOH HOH A . F 6 HOH 307 1356 307 HOH HOH A . F 6 HOH 308 1357 308 HOH HOH A . F 6 HOH 309 1358 309 HOH HOH A . F 6 HOH 310 1359 310 HOH HOH A . F 6 HOH 311 1360 311 HOH HOH A . F 6 HOH 312 1361 312 HOH HOH A . F 6 HOH 313 1362 313 HOH HOH A . F 6 HOH 314 1363 314 HOH HOH A . F 6 HOH 315 1364 315 HOH HOH A . F 6 HOH 316 1365 316 HOH HOH A . F 6 HOH 317 1366 317 HOH HOH A . F 6 HOH 318 1367 318 HOH HOH A . F 6 HOH 319 1368 319 HOH HOH A . F 6 HOH 320 1369 320 HOH HOH A . F 6 HOH 321 1370 321 HOH HOH A . F 6 HOH 322 1371 322 HOH HOH A . F 6 HOH 323 1372 323 HOH HOH A . F 6 HOH 324 1373 324 HOH HOH A . F 6 HOH 325 1374 325 HOH HOH A . F 6 HOH 326 1375 326 HOH HOH A . F 6 HOH 327 1376 327 HOH HOH A . F 6 HOH 328 1377 328 HOH HOH A . F 6 HOH 329 1378 329 HOH HOH A . F 6 HOH 330 1379 330 HOH HOH A . F 6 HOH 331 1380 331 HOH HOH A . F 6 HOH 332 1381 332 HOH HOH A . F 6 HOH 333 1382 333 HOH HOH A . F 6 HOH 334 1383 334 HOH HOH A . F 6 HOH 335 1384 335 HOH HOH A . F 6 HOH 336 1385 336 HOH HOH A . F 6 HOH 337 1386 337 HOH HOH A . F 6 HOH 338 1387 338 HOH HOH A . F 6 HOH 339 1388 339 HOH HOH A . F 6 HOH 340 1389 340 HOH HOH A . F 6 HOH 341 1390 341 HOH HOH A . F 6 HOH 342 1391 342 HOH HOH A . F 6 HOH 343 1392 343 HOH HOH A . F 6 HOH 344 1393 344 HOH HOH A . F 6 HOH 345 1394 345 HOH HOH A . F 6 HOH 346 1395 346 HOH HOH A . F 6 HOH 347 1396 347 HOH HOH A . F 6 HOH 348 1397 348 HOH HOH A . F 6 HOH 349 1398 349 HOH HOH A . F 6 HOH 350 1399 350 HOH HOH A . F 6 HOH 351 1400 351 HOH HOH A . F 6 HOH 352 1401 352 HOH HOH A . F 6 HOH 353 1402 353 HOH HOH A . F 6 HOH 354 1403 354 HOH HOH A . F 6 HOH 355 1404 355 HOH HOH A . F 6 HOH 356 1405 356 HOH HOH A . F 6 HOH 357 1406 357 HOH HOH A . F 6 HOH 358 1407 358 HOH HOH A . F 6 HOH 359 1408 359 HOH HOH A . F 6 HOH 360 1409 360 HOH HOH A . F 6 HOH 361 1410 361 HOH HOH A . F 6 HOH 362 1411 362 HOH HOH A . F 6 HOH 363 1412 363 HOH HOH A . F 6 HOH 364 1413 364 HOH HOH A . F 6 HOH 365 1414 365 HOH HOH A . F 6 HOH 366 1415 366 HOH HOH A . F 6 HOH 367 1416 367 HOH HOH A . F 6 HOH 368 1417 368 HOH HOH A . F 6 HOH 369 1418 369 HOH HOH A . F 6 HOH 370 1419 370 HOH HOH A . F 6 HOH 371 1420 371 HOH HOH A . F 6 HOH 372 1421 372 HOH HOH A . F 6 HOH 373 1422 373 HOH HOH A . F 6 HOH 374 1423 374 HOH HOH A . F 6 HOH 375 1424 375 HOH HOH A . F 6 HOH 376 1425 376 HOH HOH A . F 6 HOH 377 1426 377 HOH HOH A . F 6 HOH 378 1427 378 HOH HOH A . F 6 HOH 379 1428 379 HOH HOH A . F 6 HOH 380 1429 380 HOH HOH A . F 6 HOH 381 1430 381 HOH HOH A . F 6 HOH 382 1431 382 HOH HOH A . F 6 HOH 383 1432 383 HOH HOH A . F 6 HOH 384 1433 384 HOH HOH A . F 6 HOH 385 1434 385 HOH HOH A . F 6 HOH 386 1435 386 HOH HOH A . F 6 HOH 387 1436 387 HOH HOH A . F 6 HOH 388 1437 388 HOH HOH A . F 6 HOH 389 1438 389 HOH HOH A . F 6 HOH 390 1439 390 HOH HOH A . F 6 HOH 391 1440 391 HOH HOH A . F 6 HOH 392 1441 392 HOH HOH A . F 6 HOH 393 1442 393 HOH HOH A . F 6 HOH 394 1443 394 HOH HOH A . F 6 HOH 395 1444 395 HOH HOH A . F 6 HOH 396 1445 396 HOH HOH A . F 6 HOH 397 1446 397 HOH HOH A . F 6 HOH 398 1447 398 HOH HOH A . F 6 HOH 399 1448 399 HOH HOH A . F 6 HOH 400 1449 400 HOH HOH A . F 6 HOH 401 1450 401 HOH HOH A . F 6 HOH 402 1451 402 HOH HOH A . F 6 HOH 403 1452 403 HOH HOH A . F 6 HOH 404 1453 404 HOH HOH A . F 6 HOH 405 1454 405 HOH HOH A . F 6 HOH 406 1455 406 HOH HOH A . F 6 HOH 407 1456 407 HOH HOH A . F 6 HOH 408 1457 408 HOH HOH A . F 6 HOH 409 1458 409 HOH HOH A . F 6 HOH 410 1459 410 HOH HOH A . F 6 HOH 411 1460 411 HOH HOH A . F 6 HOH 412 1461 412 HOH HOH A . F 6 HOH 413 1462 413 HOH HOH A . F 6 HOH 414 1463 414 HOH HOH A . F 6 HOH 415 1464 415 HOH HOH A . F 6 HOH 416 1465 416 HOH HOH A . F 6 HOH 417 1466 417 HOH HOH A . F 6 HOH 418 1467 418 HOH HOH A . F 6 HOH 419 1468 419 HOH HOH A . F 6 HOH 420 1469 420 HOH HOH A . F 6 HOH 421 1470 421 HOH HOH A . F 6 HOH 422 1471 422 HOH HOH A . F 6 HOH 423 1472 423 HOH HOH A . F 6 HOH 424 1473 424 HOH HOH A . F 6 HOH 425 1474 425 HOH HOH A . F 6 HOH 426 1475 426 HOH HOH A . F 6 HOH 427 1476 427 HOH HOH A . F 6 HOH 428 1477 428 HOH HOH A . F 6 HOH 429 1478 429 HOH HOH A . F 6 HOH 430 1479 430 HOH HOH A . F 6 HOH 431 1480 431 HOH HOH A . F 6 HOH 432 1481 432 HOH HOH A . F 6 HOH 433 1482 433 HOH HOH A . F 6 HOH 434 1483 434 HOH HOH A . F 6 HOH 435 1484 435 HOH HOH A . F 6 HOH 436 1485 436 HOH HOH A . F 6 HOH 437 1486 437 HOH HOH A . F 6 HOH 438 1487 438 HOH HOH A . F 6 HOH 439 1488 439 HOH HOH A . F 6 HOH 440 1489 440 HOH HOH A . F 6 HOH 441 1490 441 HOH HOH A . F 6 HOH 442 1491 442 HOH HOH A . F 6 HOH 443 1492 443 HOH HOH A . F 6 HOH 444 1493 444 HOH HOH A . F 6 HOH 445 1494 445 HOH HOH A . F 6 HOH 446 1495 446 HOH HOH A . F 6 HOH 447 1496 447 HOH HOH A . F 6 HOH 448 1497 448 HOH HOH A . F 6 HOH 449 1498 449 HOH HOH A . F 6 HOH 450 1499 450 HOH HOH A . F 6 HOH 451 1500 451 HOH HOH A . F 6 HOH 452 1501 452 HOH HOH A . F 6 HOH 453 1502 453 HOH HOH A . F 6 HOH 454 1503 454 HOH HOH A . F 6 HOH 455 1504 455 HOH HOH A . F 6 HOH 456 1505 456 HOH HOH A . F 6 HOH 457 1506 457 HOH HOH A . F 6 HOH 458 1507 458 HOH HOH A . F 6 HOH 459 1508 459 HOH HOH A . F 6 HOH 460 1509 460 HOH HOH A . F 6 HOH 461 1510 461 HOH HOH A . F 6 HOH 462 1511 462 HOH HOH A . F 6 HOH 463 1512 463 HOH HOH A . F 6 HOH 464 1513 464 HOH HOH A . F 6 HOH 465 1514 465 HOH HOH A . F 6 HOH 466 1515 466 HOH HOH A . F 6 HOH 467 1516 467 HOH HOH A . F 6 HOH 468 1517 468 HOH HOH A . F 6 HOH 469 1518 469 HOH HOH A . F 6 HOH 470 1519 470 HOH HOH A . F 6 HOH 471 1520 471 HOH HOH A . F 6 HOH 472 1521 472 HOH HOH A . F 6 HOH 473 1522 473 HOH HOH A . F 6 HOH 474 1523 474 HOH HOH A . F 6 HOH 475 1524 475 HOH HOH A . F 6 HOH 476 1525 476 HOH HOH A . F 6 HOH 477 1526 477 HOH HOH A . F 6 HOH 478 1527 478 HOH HOH A . F 6 HOH 479 1528 479 HOH HOH A . F 6 HOH 480 1529 480 HOH HOH A . F 6 HOH 481 1530 481 HOH HOH A . F 6 HOH 482 1531 482 HOH HOH A . F 6 HOH 483 1532 483 HOH HOH A . F 6 HOH 484 1533 484 HOH HOH A . F 6 HOH 485 1534 485 HOH HOH A . F 6 HOH 486 1535 486 HOH HOH A . F 6 HOH 487 1536 487 HOH HOH A . F 6 HOH 488 1537 488 HOH HOH A . F 6 HOH 489 1538 489 HOH HOH A . F 6 HOH 490 1539 490 HOH HOH A . F 6 HOH 491 1540 491 HOH HOH A . F 6 HOH 492 1541 492 HOH HOH A . F 6 HOH 493 1542 493 HOH HOH A . F 6 HOH 494 1543 494 HOH HOH A . F 6 HOH 495 1544 495 HOH HOH A . F 6 HOH 496 1545 496 HOH HOH A . F 6 HOH 497 1546 497 HOH HOH A . F 6 HOH 498 1547 498 HOH HOH A . F 6 HOH 499 1548 499 HOH HOH A . F 6 HOH 500 1549 500 HOH HOH A . F 6 HOH 501 1550 501 HOH HOH A . F 6 HOH 502 1551 502 HOH HOH A . F 6 HOH 503 1552 503 HOH HOH A . F 6 HOH 504 1553 504 HOH HOH A . F 6 HOH 505 1554 505 HOH HOH A . F 6 HOH 506 1555 506 HOH HOH A . F 6 HOH 507 1556 507 HOH HOH A . F 6 HOH 508 1557 508 HOH HOH A . F 6 HOH 509 1558 509 HOH HOH A . F 6 HOH 510 1559 510 HOH HOH A . F 6 HOH 511 1560 511 HOH HOH A . F 6 HOH 512 1561 512 HOH HOH A . F 6 HOH 513 1562 513 HOH HOH A . F 6 HOH 514 1563 514 HOH HOH A . F 6 HOH 515 1564 515 HOH HOH A . F 6 HOH 516 1565 516 HOH HOH A . F 6 HOH 517 1566 517 HOH HOH A . F 6 HOH 518 1567 518 HOH HOH A . F 6 HOH 519 1568 519 HOH HOH A . F 6 HOH 520 1569 520 HOH HOH A . F 6 HOH 521 1570 521 HOH HOH A . F 6 HOH 522 1571 522 HOH HOH A . F 6 HOH 523 1572 523 HOH HOH A . F 6 HOH 524 1573 524 HOH HOH A . F 6 HOH 525 1574 525 HOH HOH A . F 6 HOH 526 1575 526 HOH HOH A . F 6 HOH 527 1576 527 HOH HOH A . F 6 HOH 528 1577 528 HOH HOH A . F 6 HOH 529 1578 529 HOH HOH A . F 6 HOH 530 1579 530 HOH HOH A . F 6 HOH 531 1580 531 HOH HOH A . F 6 HOH 532 1581 532 HOH HOH A . F 6 HOH 533 1582 533 HOH HOH A . F 6 HOH 534 1583 534 HOH HOH A . F 6 HOH 535 1584 535 HOH HOH A . F 6 HOH 536 1585 536 HOH HOH A . F 6 HOH 537 1586 537 HOH HOH A . F 6 HOH 538 1587 538 HOH HOH A . F 6 HOH 539 1588 539 HOH HOH A . F 6 HOH 540 1589 540 HOH HOH A . F 6 HOH 541 1590 541 HOH HOH A . F 6 HOH 542 1591 542 HOH HOH A . F 6 HOH 543 1592 543 HOH HOH A . F 6 HOH 544 1593 544 HOH HOH A . F 6 HOH 545 1594 545 HOH HOH A . F 6 HOH 546 1595 546 HOH HOH A . F 6 HOH 547 1596 547 HOH HOH A . F 6 HOH 548 1597 548 HOH HOH A . F 6 HOH 549 1598 549 HOH HOH A . F 6 HOH 550 1599 550 HOH HOH A . F 6 HOH 551 1600 551 HOH HOH A . F 6 HOH 552 1601 552 HOH HOH A . F 6 HOH 553 1602 553 HOH HOH A . F 6 HOH 554 1603 554 HOH HOH A . F 6 HOH 555 1604 555 HOH HOH A . F 6 HOH 556 1605 556 HOH HOH A . F 6 HOH 557 1606 557 HOH HOH A . F 6 HOH 558 1607 558 HOH HOH A . F 6 HOH 559 1608 559 HOH HOH A . F 6 HOH 560 1609 560 HOH HOH A . F 6 HOH 561 1610 561 HOH HOH A . F 6 HOH 562 1611 562 HOH HOH A . F 6 HOH 563 1612 563 HOH HOH A . F 6 HOH 564 1613 564 HOH HOH A . F 6 HOH 565 1614 565 HOH HOH A . F 6 HOH 566 1615 566 HOH HOH A . F 6 HOH 567 1616 567 HOH HOH A . F 6 HOH 568 1617 568 HOH HOH A . F 6 HOH 569 1618 569 HOH HOH A . F 6 HOH 570 1619 570 HOH HOH A . F 6 HOH 571 1620 571 HOH HOH A . F 6 HOH 572 1621 572 HOH HOH A . F 6 HOH 573 1622 573 HOH HOH A . F 6 HOH 574 1623 574 HOH HOH A . F 6 HOH 575 1624 575 HOH HOH A . F 6 HOH 576 1625 576 HOH HOH A . F 6 HOH 577 1626 577 HOH HOH A . F 6 HOH 578 1627 578 HOH HOH A . F 6 HOH 579 1628 579 HOH HOH A . F 6 HOH 580 1629 580 HOH HOH A . F 6 HOH 581 1630 581 HOH HOH A . F 6 HOH 582 1631 582 HOH HOH A . F 6 HOH 583 1632 583 HOH HOH A . F 6 HOH 584 1633 584 HOH HOH A . F 6 HOH 585 1634 585 HOH HOH A . F 6 HOH 586 1635 586 HOH HOH A . F 6 HOH 587 1636 587 HOH HOH A . F 6 HOH 588 1637 588 HOH HOH A . F 6 HOH 589 1638 589 HOH HOH A . F 6 HOH 590 1639 590 HOH HOH A . F 6 HOH 591 1640 591 HOH HOH A . F 6 HOH 592 1641 592 HOH HOH A . F 6 HOH 593 1642 593 HOH HOH A . F 6 HOH 594 1643 594 HOH HOH A . F 6 HOH 595 1644 595 HOH HOH A . F 6 HOH 596 1645 596 HOH HOH A . F 6 HOH 597 1646 597 HOH HOH A . F 6 HOH 598 1647 598 HOH HOH A . F 6 HOH 599 1648 599 HOH HOH A . F 6 HOH 600 1649 600 HOH HOH A . F 6 HOH 601 1650 601 HOH HOH A . F 6 HOH 602 1651 602 HOH HOH A . F 6 HOH 603 1652 603 HOH HOH A . F 6 HOH 604 1653 604 HOH HOH A . F 6 HOH 605 1654 605 HOH HOH A . F 6 HOH 606 1655 606 HOH HOH A . F 6 HOH 607 1656 607 HOH HOH A . F 6 HOH 608 1657 608 HOH HOH A . F 6 HOH 609 1658 609 HOH HOH A . F 6 HOH 610 1659 610 HOH HOH A . F 6 HOH 611 1660 611 HOH HOH A . F 6 HOH 612 1661 612 HOH HOH A . F 6 HOH 613 1662 613 HOH HOH A . F 6 HOH 614 1663 614 HOH HOH A . F 6 HOH 615 1664 615 HOH HOH A . F 6 HOH 616 1665 616 HOH HOH A . F 6 HOH 617 1666 617 HOH HOH A . F 6 HOH 618 1667 618 HOH HOH A . F 6 HOH 619 1668 619 HOH HOH A . F 6 HOH 620 1669 620 HOH HOH A . F 6 HOH 621 1670 621 HOH HOH A . F 6 HOH 622 1671 622 HOH HOH A . F 6 HOH 623 1672 623 HOH HOH A . F 6 HOH 624 1673 624 HOH HOH A . F 6 HOH 625 1674 625 HOH HOH A . F 6 HOH 626 1675 626 HOH HOH A . F 6 HOH 627 1676 627 HOH HOH A . F 6 HOH 628 1677 628 HOH HOH A . F 6 HOH 629 1678 629 HOH HOH A . F 6 HOH 630 1679 630 HOH HOH A . F 6 HOH 631 1680 631 HOH HOH A . F 6 HOH 632 1681 632 HOH HOH A . F 6 HOH 633 1682 633 HOH HOH A . F 6 HOH 634 1683 634 HOH HOH A . F 6 HOH 635 1684 635 HOH HOH A . F 6 HOH 636 1685 636 HOH HOH A . F 6 HOH 637 1686 637 HOH HOH A . F 6 HOH 638 1687 638 HOH HOH A . F 6 HOH 639 1688 639 HOH HOH A . F 6 HOH 640 1689 640 HOH HOH A . F 6 HOH 641 1690 641 HOH HOH A . F 6 HOH 642 1691 642 HOH HOH A . F 6 HOH 643 1692 643 HOH HOH A . F 6 HOH 644 1693 644 HOH HOH A . F 6 HOH 645 1694 645 HOH HOH A . F 6 HOH 646 1695 646 HOH HOH A . F 6 HOH 647 1696 647 HOH HOH A . F 6 HOH 648 1697 648 HOH HOH A . F 6 HOH 649 1698 649 HOH HOH A . F 6 HOH 650 1699 650 HOH HOH A . F 6 HOH 651 1700 651 HOH HOH A . F 6 HOH 652 1701 652 HOH HOH A . F 6 HOH 653 1702 653 HOH HOH A . F 6 HOH 654 1703 654 HOH HOH A . F 6 HOH 655 1704 655 HOH HOH A . F 6 HOH 656 1705 656 HOH HOH A . F 6 HOH 657 1706 657 HOH HOH A . F 6 HOH 658 1707 658 HOH HOH A . F 6 HOH 659 1708 659 HOH HOH A . F 6 HOH 660 1709 660 HOH HOH A . F 6 HOH 661 1710 661 HOH HOH A . F 6 HOH 662 1711 662 HOH HOH A . F 6 HOH 663 1712 663 HOH HOH A . F 6 HOH 664 1713 664 HOH HOH A . F 6 HOH 665 1714 665 HOH HOH A . F 6 HOH 666 1715 666 HOH HOH A . F 6 HOH 667 1716 667 HOH HOH A . F 6 HOH 668 1717 668 HOH HOH A . F 6 HOH 669 1718 669 HOH HOH A . F 6 HOH 670 1719 670 HOH HOH A . F 6 HOH 671 1720 671 HOH HOH A . F 6 HOH 672 1721 672 HOH HOH A . F 6 HOH 673 1722 673 HOH HOH A . F 6 HOH 674 1723 674 HOH HOH A . F 6 HOH 675 1724 675 HOH HOH A . F 6 HOH 676 1725 676 HOH HOH A . F 6 HOH 677 1726 677 HOH HOH A . F 6 HOH 678 1727 678 HOH HOH A . F 6 HOH 679 1728 679 HOH HOH A . F 6 HOH 680 1729 680 HOH HOH A . F 6 HOH 681 1730 681 HOH HOH A . F 6 HOH 682 1731 682 HOH HOH A . F 6 HOH 683 1732 683 HOH HOH A . F 6 HOH 684 1733 684 HOH HOH A . F 6 HOH 685 1734 685 HOH HOH A . F 6 HOH 686 1735 686 HOH HOH A . F 6 HOH 687 1736 687 HOH HOH A . F 6 HOH 688 1737 688 HOH HOH A . F 6 HOH 689 1738 689 HOH HOH A . F 6 HOH 690 1739 690 HOH HOH A . F 6 HOH 691 1740 691 HOH HOH A . F 6 HOH 692 1741 692 HOH HOH A . F 6 HOH 693 1742 693 HOH HOH A . F 6 HOH 694 1743 694 HOH HOH A . F 6 HOH 695 1744 695 HOH HOH A . F 6 HOH 696 1745 696 HOH HOH A . F 6 HOH 697 1746 697 HOH HOH A . F 6 HOH 698 1747 698 HOH HOH A . F 6 HOH 699 1748 699 HOH HOH A . F 6 HOH 700 1749 700 HOH HOH A . F 6 HOH 701 1750 701 HOH HOH A . F 6 HOH 702 1751 702 HOH HOH A . F 6 HOH 703 1752 703 HOH HOH A . F 6 HOH 704 1753 704 HOH HOH A . F 6 HOH 705 1754 705 HOH HOH A . F 6 HOH 706 1755 706 HOH HOH A . F 6 HOH 707 1756 707 HOH HOH A . F 6 HOH 708 1757 708 HOH HOH A . F 6 HOH 709 1758 709 HOH HOH A . F 6 HOH 710 1759 710 HOH HOH A . F 6 HOH 711 1760 711 HOH HOH A . F 6 HOH 712 1761 712 HOH HOH A . F 6 HOH 713 1762 713 HOH HOH A . F 6 HOH 714 1763 714 HOH HOH A . F 6 HOH 715 1764 715 HOH HOH A . F 6 HOH 716 1765 716 HOH HOH A . F 6 HOH 717 1766 717 HOH HOH A . F 6 HOH 718 1767 718 HOH HOH A . F 6 HOH 719 1768 719 HOH HOH A . F 6 HOH 720 1769 720 HOH HOH A . F 6 HOH 721 1770 721 HOH HOH A . F 6 HOH 722 1771 722 HOH HOH A . F 6 HOH 723 1772 723 HOH HOH A . F 6 HOH 724 1773 724 HOH HOH A . F 6 HOH 725 1774 725 HOH HOH A . F 6 HOH 726 1775 726 HOH HOH A . F 6 HOH 727 1776 727 HOH HOH A . F 6 HOH 728 1777 728 HOH HOH A . F 6 HOH 729 1778 729 HOH HOH A . F 6 HOH 730 1779 730 HOH HOH A . F 6 HOH 731 1780 731 HOH HOH A . F 6 HOH 732 1781 732 HOH HOH A . F 6 HOH 733 1782 733 HOH HOH A . F 6 HOH 734 1783 734 HOH HOH A . F 6 HOH 735 1784 735 HOH HOH A . F 6 HOH 736 1785 736 HOH HOH A . F 6 HOH 737 1786 737 HOH HOH A . F 6 HOH 738 1787 738 HOH HOH A . F 6 HOH 739 1788 739 HOH HOH A . F 6 HOH 740 1789 740 HOH HOH A . F 6 HOH 741 1790 741 HOH HOH A . F 6 HOH 742 1791 742 HOH HOH A . F 6 HOH 743 1792 743 HOH HOH A . F 6 HOH 744 1793 744 HOH HOH A . F 6 HOH 745 1794 745 HOH HOH A . F 6 HOH 746 1795 746 HOH HOH A . F 6 HOH 747 1796 747 HOH HOH A . F 6 HOH 748 1797 748 HOH HOH A . F 6 HOH 749 1798 749 HOH HOH A . F 6 HOH 750 1799 750 HOH HOH A . F 6 HOH 751 1800 751 HOH HOH A . F 6 HOH 752 1801 752 HOH HOH A . F 6 HOH 753 1802 753 HOH HOH A . F 6 HOH 754 1803 754 HOH HOH A . F 6 HOH 755 1804 755 HOH HOH A . F 6 HOH 756 1805 756 HOH HOH A . F 6 HOH 757 1806 757 HOH HOH A . F 6 HOH 758 1807 758 HOH HOH A . F 6 HOH 759 1808 759 HOH HOH A . F 6 HOH 760 1809 760 HOH HOH A . F 6 HOH 761 1810 761 HOH HOH A . F 6 HOH 762 1811 762 HOH HOH A . F 6 HOH 763 1812 763 HOH HOH A . F 6 HOH 764 1813 764 HOH HOH A . F 6 HOH 765 1814 765 HOH HOH A . F 6 HOH 766 1815 766 HOH HOH A . F 6 HOH 767 1816 767 HOH HOH A . F 6 HOH 768 1817 768 HOH HOH A . F 6 HOH 769 1818 769 HOH HOH A . F 6 HOH 770 1819 770 HOH HOH A . F 6 HOH 771 1820 771 HOH HOH A . F 6 HOH 772 1821 772 HOH HOH A . F 6 HOH 773 1822 773 HOH HOH A . F 6 HOH 774 1823 774 HOH HOH A . F 6 HOH 775 1824 775 HOH HOH A . F 6 HOH 776 1825 776 HOH HOH A . F 6 HOH 777 1826 777 HOH HOH A . F 6 HOH 778 1827 778 HOH HOH A . F 6 HOH 779 1828 779 HOH HOH A . F 6 HOH 780 1829 780 HOH HOH A . F 6 HOH 781 1830 781 HOH HOH A . F 6 HOH 782 1831 782 HOH HOH A . F 6 HOH 783 1832 783 HOH HOH A . F 6 HOH 784 1833 784 HOH HOH A . F 6 HOH 785 1834 785 HOH HOH A . F 6 HOH 786 1835 786 HOH HOH A . F 6 HOH 787 1836 787 HOH HOH A . F 6 HOH 788 1837 788 HOH HOH A . F 6 HOH 789 1838 789 HOH HOH A . F 6 HOH 790 1839 790 HOH HOH A . F 6 HOH 791 1840 791 HOH HOH A . F 6 HOH 792 1841 792 HOH HOH A . F 6 HOH 793 1842 793 HOH HOH A . F 6 HOH 794 1843 794 HOH HOH A . F 6 HOH 795 1844 795 HOH HOH A . F 6 HOH 796 1845 796 HOH HOH A . F 6 HOH 797 1846 797 HOH HOH A . F 6 HOH 798 1847 798 HOH HOH A . F 6 HOH 799 1848 799 HOH HOH A . F 6 HOH 800 1849 800 HOH HOH A . F 6 HOH 801 1850 801 HOH HOH A . F 6 HOH 802 1851 802 HOH HOH A . F 6 HOH 803 1852 803 HOH HOH A . F 6 HOH 804 1853 804 HOH HOH A . F 6 HOH 805 1854 805 HOH HOH A . F 6 HOH 806 1855 806 HOH HOH A . F 6 HOH 807 1856 807 HOH HOH A . F 6 HOH 808 1857 808 HOH HOH A . F 6 HOH 809 1858 809 HOH HOH A . F 6 HOH 810 1859 810 HOH HOH A . F 6 HOH 811 1860 811 HOH HOH A . F 6 HOH 812 1861 812 HOH HOH A . F 6 HOH 813 1862 813 HOH HOH A . F 6 HOH 814 1863 814 HOH HOH A . F 6 HOH 815 1864 815 HOH HOH A . F 6 HOH 816 1865 816 HOH HOH A . F 6 HOH 817 1866 817 HOH HOH A . F 6 HOH 818 1867 818 HOH HOH A . F 6 HOH 819 1868 819 HOH HOH A . F 6 HOH 820 1869 820 HOH HOH A . F 6 HOH 821 1870 821 HOH HOH A . F 6 HOH 822 1871 822 HOH HOH A . F 6 HOH 823 1872 823 HOH HOH A . F 6 HOH 824 1873 824 HOH HOH A . F 6 HOH 825 1874 825 HOH HOH A . F 6 HOH 826 1875 826 HOH HOH A . F 6 HOH 827 1876 827 HOH HOH A . F 6 HOH 828 1877 828 HOH HOH A . F 6 HOH 829 1878 829 HOH HOH A . F 6 HOH 830 1879 830 HOH HOH A . F 6 HOH 831 1880 831 HOH HOH A . F 6 HOH 832 1881 832 HOH HOH A . F 6 HOH 833 1882 833 HOH HOH A . F 6 HOH 834 1883 834 HOH HOH A . F 6 HOH 835 1884 835 HOH HOH A . F 6 HOH 836 1885 836 HOH HOH A . F 6 HOH 837 1886 837 HOH HOH A . F 6 HOH 838 1887 838 HOH HOH A . F 6 HOH 839 1888 839 HOH HOH A . F 6 HOH 840 1889 840 HOH HOH A . F 6 HOH 841 1890 841 HOH HOH A . F 6 HOH 842 1891 842 HOH HOH A . F 6 HOH 843 1892 843 HOH HOH A . F 6 HOH 844 1893 844 HOH HOH A . F 6 HOH 845 1894 845 HOH HOH A . F 6 HOH 846 1895 846 HOH HOH A . F 6 HOH 847 1896 847 HOH HOH A . F 6 HOH 848 1897 848 HOH HOH A . F 6 HOH 849 1898 849 HOH HOH A . F 6 HOH 850 1899 850 HOH HOH A . F 6 HOH 851 1900 851 HOH HOH A . F 6 HOH 852 1901 852 HOH HOH A . F 6 HOH 853 1902 853 HOH HOH A . F 6 HOH 854 1903 854 HOH HOH A . F 6 HOH 855 1904 855 HOH HOH A . F 6 HOH 856 1905 856 HOH HOH A . F 6 HOH 857 1906 857 HOH HOH A . F 6 HOH 858 1907 858 HOH HOH A . F 6 HOH 859 1908 859 HOH HOH A . F 6 HOH 860 1909 860 HOH HOH A . F 6 HOH 861 1910 861 HOH HOH A . F 6 HOH 862 1911 862 HOH HOH A . F 6 HOH 863 1912 863 HOH HOH A . F 6 HOH 864 1913 864 HOH HOH A . F 6 HOH 865 1914 865 HOH HOH A . F 6 HOH 866 1915 866 HOH HOH A . F 6 HOH 867 1916 867 HOH HOH A . F 6 HOH 868 1917 868 HOH HOH A . F 6 HOH 869 1918 869 HOH HOH A . F 6 HOH 870 1919 870 HOH HOH A . F 6 HOH 871 1920 871 HOH HOH A . F 6 HOH 872 1921 872 HOH HOH A . F 6 HOH 873 1922 873 HOH HOH A . F 6 HOH 874 1923 874 HOH HOH A . F 6 HOH 875 1924 875 HOH HOH A . F 6 HOH 876 1925 876 HOH HOH A . F 6 HOH 877 1926 877 HOH HOH A . F 6 HOH 878 1927 878 HOH HOH A . F 6 HOH 879 1928 879 HOH HOH A . F 6 HOH 880 1929 880 HOH HOH A . F 6 HOH 881 1930 881 HOH HOH A . F 6 HOH 882 1931 882 HOH HOH A . F 6 HOH 883 1932 883 HOH HOH A . F 6 HOH 884 1933 884 HOH HOH A . F 6 HOH 885 1934 885 HOH HOH A . F 6 HOH 886 1935 886 HOH HOH A . F 6 HOH 887 1936 887 HOH HOH A . F 6 HOH 888 1937 888 HOH HOH A . F 6 HOH 889 1938 889 HOH HOH A . F 6 HOH 890 1939 890 HOH HOH A . F 6 HOH 891 1940 891 HOH HOH A . F 6 HOH 892 1941 892 HOH HOH A . F 6 HOH 893 1942 893 HOH HOH A . F 6 HOH 894 1943 894 HOH HOH A . F 6 HOH 895 1944 895 HOH HOH A . F 6 HOH 896 1945 896 HOH HOH A . F 6 HOH 897 1946 897 HOH HOH A . F 6 HOH 898 1947 898 HOH HOH A . F 6 HOH 899 1948 899 HOH HOH A . F 6 HOH 900 1949 900 HOH HOH A . F 6 HOH 901 1950 901 HOH HOH A . F 6 HOH 902 1951 902 HOH HOH A . F 6 HOH 903 1952 903 HOH HOH A . F 6 HOH 904 1953 904 HOH HOH A . F 6 HOH 905 1954 905 HOH HOH A . F 6 HOH 906 1955 906 HOH HOH A . F 6 HOH 907 1956 907 HOH HOH A . F 6 HOH 908 1957 908 HOH HOH A . F 6 HOH 909 1958 909 HOH HOH A . F 6 HOH 910 1959 910 HOH HOH A . F 6 HOH 911 1960 911 HOH HOH A . F 6 HOH 912 1961 912 HOH HOH A . F 6 HOH 913 1962 913 HOH HOH A . F 6 HOH 914 1963 914 HOH HOH A . F 6 HOH 915 1964 915 HOH HOH A . F 6 HOH 916 1965 916 HOH HOH A . F 6 HOH 917 1966 917 HOH HOH A . F 6 HOH 918 1967 918 HOH HOH A . F 6 HOH 919 1968 919 HOH HOH A . F 6 HOH 920 1969 920 HOH HOH A . F 6 HOH 921 1970 921 HOH HOH A . F 6 HOH 922 1971 922 HOH HOH A . F 6 HOH 923 1972 923 HOH HOH A . F 6 HOH 924 1973 924 HOH HOH A . F 6 HOH 925 1974 925 HOH HOH A . F 6 HOH 926 1975 926 HOH HOH A . F 6 HOH 927 1976 927 HOH HOH A . F 6 HOH 928 1977 928 HOH HOH A . F 6 HOH 929 1978 929 HOH HOH A . F 6 HOH 930 1979 930 HOH HOH A . F 6 HOH 931 1980 931 HOH HOH A . F 6 HOH 932 1981 932 HOH HOH A . F 6 HOH 933 1982 933 HOH HOH A . F 6 HOH 934 1983 934 HOH HOH A . F 6 HOH 935 1984 935 HOH HOH A . F 6 HOH 936 1985 936 HOH HOH A . F 6 HOH 937 1986 937 HOH HOH A . F 6 HOH 938 1987 938 HOH HOH A . F 6 HOH 939 1988 939 HOH HOH A . F 6 HOH 940 1989 940 HOH HOH A . F 6 HOH 941 1990 941 HOH HOH A . F 6 HOH 942 1991 942 HOH HOH A . F 6 HOH 943 1992 943 HOH HOH A . F 6 HOH 944 1993 944 HOH HOH A . F 6 HOH 945 1994 945 HOH HOH A . F 6 HOH 946 1995 946 HOH HOH A . F 6 HOH 947 1996 947 HOH HOH A . F 6 HOH 948 1997 948 HOH HOH A . F 6 HOH 949 1998 949 HOH HOH A . F 6 HOH 950 1999 950 HOH HOH A . F 6 HOH 951 2000 951 HOH HOH A . F 6 HOH 952 2001 952 HOH HOH A . F 6 HOH 953 2002 953 HOH HOH A . F 6 HOH 954 2003 954 HOH HOH A . F 6 HOH 955 2004 955 HOH HOH A . F 6 HOH 956 2005 956 HOH HOH A . F 6 HOH 957 2006 957 HOH HOH A . F 6 HOH 958 2007 958 HOH HOH A . F 6 HOH 959 2008 959 HOH HOH A . F 6 HOH 960 2009 960 HOH HOH A . F 6 HOH 961 2010 961 HOH HOH A . F 6 HOH 962 2011 962 HOH HOH A . F 6 HOH 963 2012 963 HOH HOH A . F 6 HOH 964 2013 964 HOH HOH A . F 6 HOH 965 2014 965 HOH HOH A . F 6 HOH 966 2015 966 HOH HOH A . F 6 HOH 967 2016 967 HOH HOH A . F 6 HOH 968 2017 968 HOH HOH A . F 6 HOH 969 2018 969 HOH HOH A . F 6 HOH 970 2019 970 HOH HOH A . F 6 HOH 971 2020 971 HOH HOH A . F 6 HOH 972 2021 972 HOH HOH A . F 6 HOH 973 2022 973 HOH HOH A . F 6 HOH 974 2023 974 HOH HOH A . F 6 HOH 975 2024 975 HOH HOH A . F 6 HOH 976 2025 976 HOH HOH A . F 6 HOH 977 2026 977 HOH HOH A . F 6 HOH 978 2027 978 HOH HOH A . F 6 HOH 979 2028 979 HOH HOH A . F 6 HOH 980 2029 980 HOH HOH A . F 6 HOH 981 2030 981 HOH HOH A . F 6 HOH 982 2031 982 HOH HOH A . F 6 HOH 983 2032 983 HOH HOH A . F 6 HOH 984 2033 984 HOH HOH A . F 6 HOH 985 2034 985 HOH HOH A . F 6 HOH 986 2035 986 HOH HOH A . F 6 HOH 987 2036 987 HOH HOH A . F 6 HOH 988 2037 988 HOH HOH A . F 6 HOH 989 2038 989 HOH HOH A . F 6 HOH 990 2039 990 HOH HOH A . F 6 HOH 991 2040 991 HOH HOH A . F 6 HOH 992 2041 992 HOH HOH A . F 6 HOH 993 2042 993 HOH HOH A . F 6 HOH 994 2043 994 HOH HOH A . F 6 HOH 995 2044 995 HOH HOH A . F 6 HOH 996 2045 996 HOH HOH A . F 6 HOH 997 2046 997 HOH HOH A . F 6 HOH 998 2047 998 HOH HOH A . F 6 HOH 999 2048 999 HOH HOH A . F 6 HOH 1000 2049 1000 HOH HOH A . F 6 HOH 1001 2050 1001 HOH HOH A . F 6 HOH 1002 2051 1002 HOH HOH A . F 6 HOH 1003 2052 1003 HOH HOH A . F 6 HOH 1004 2053 1004 HOH HOH A . F 6 HOH 1005 2054 1005 HOH HOH A . F 6 HOH 1006 2055 1006 HOH HOH A . F 6 HOH 1007 2056 1007 HOH HOH A . F 6 HOH 1008 2057 1008 HOH HOH A . F 6 HOH 1009 2058 1009 HOH HOH A . F 6 HOH 1010 2059 1010 HOH HOH A . F 6 HOH 1011 2060 1011 HOH HOH A . F 6 HOH 1012 2061 1012 HOH HOH A . F 6 HOH 1013 2062 1013 HOH HOH A . F 6 HOH 1014 2063 1014 HOH HOH A . F 6 HOH 1015 2064 1015 HOH HOH A . F 6 HOH 1016 2065 1016 HOH HOH A . F 6 HOH 1017 2066 1017 HOH HOH A . F 6 HOH 1018 2067 1018 HOH HOH A . F 6 HOH 1019 2068 1019 HOH HOH A . F 6 HOH 1020 2069 1020 HOH HOH A . F 6 HOH 1021 2070 1021 HOH HOH A . F 6 HOH 1022 2071 1022 HOH HOH A . F 6 HOH 1023 2072 1023 HOH HOH A . F 6 HOH 1024 2073 1024 HOH HOH A . F 6 HOH 1025 2074 1025 HOH HOH A . F 6 HOH 1026 2075 1026 HOH HOH A . F 6 HOH 1027 2076 1027 HOH HOH A . F 6 HOH 1028 2077 1028 HOH HOH A . F 6 HOH 1029 2078 1029 HOH HOH A . F 6 HOH 1030 2079 1030 HOH HOH A . F 6 HOH 1031 2080 1031 HOH HOH A . F 6 HOH 1032 2081 1032 HOH HOH A . F 6 HOH 1033 2082 1033 HOH HOH A . F 6 HOH 1034 2083 1034 HOH HOH A . F 6 HOH 1035 2084 1035 HOH HOH A . F 6 HOH 1036 2085 1036 HOH HOH A . F 6 HOH 1037 2086 1037 HOH HOH A . F 6 HOH 1038 2087 1038 HOH HOH A . F 6 HOH 1039 2088 1039 HOH HOH A . F 6 HOH 1040 2089 1040 HOH HOH A . F 6 HOH 1041 2090 1041 HOH HOH A . F 6 HOH 1042 2091 1042 HOH HOH A . F 6 HOH 1043 2092 1043 HOH HOH A . F 6 HOH 1044 2093 1044 HOH HOH A . F 6 HOH 1045 2094 1045 HOH HOH A . F 6 HOH 1046 2095 1046 HOH HOH A . F 6 HOH 1047 2096 1047 HOH HOH A . F 6 HOH 1048 2097 1048 HOH HOH A . F 6 HOH 1049 2098 1049 HOH HOH A . F 6 HOH 1050 2099 1050 HOH HOH A . F 6 HOH 1051 2100 1051 HOH HOH A . F 6 HOH 1052 2101 1052 HOH HOH A . F 6 HOH 1053 2102 1053 HOH HOH A . F 6 HOH 1054 2103 1054 HOH HOH A . F 6 HOH 1055 2104 1055 HOH HOH A . F 6 HOH 1056 2105 1056 HOH HOH A . F 6 HOH 1057 2106 1057 HOH HOH A . F 6 HOH 1058 2107 1058 HOH HOH A . F 6 HOH 1059 2108 1059 HOH HOH A . F 6 HOH 1060 2109 1060 HOH HOH A . F 6 HOH 1061 2110 1061 HOH HOH A . F 6 HOH 1062 2111 1062 HOH HOH A . F 6 HOH 1063 2112 1063 HOH HOH A . F 6 HOH 1064 2113 1064 HOH HOH A . F 6 HOH 1065 2114 1065 HOH HOH A . F 6 HOH 1066 2115 1066 HOH HOH A . F 6 HOH 1067 2116 1067 HOH HOH A . F 6 HOH 1068 2117 1068 HOH HOH A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 93.0 ? 2 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 98.0 ? 3 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 165.8 ? 4 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 104.9 ? 5 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 91.9 ? 6 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 93.8 ? 7 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O11 ? D SWA . ? A SWA 1048 ? 1_555 161.9 ? 8 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O11 ? D SWA . ? A SWA 1048 ? 1_555 85.9 ? 9 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O11 ? D SWA . ? A SWA 1048 ? 1_555 80.8 ? 10 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O11 ? D SWA . ? A SWA 1048 ? 1_555 93.2 ? 11 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O13 ? D SWA . ? A SWA 1048 ? 1_555 88.8 ? 12 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O13 ? D SWA . ? A SWA 1048 ? 1_555 83.8 ? 13 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O13 ? D SWA . ? A SWA 1048 ? 1_555 87.5 ? 14 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O13 ? D SWA . ? A SWA 1048 ? 1_555 165.8 ? 15 O11 ? D SWA . ? A SWA 1048 ? 1_555 ZN ? C ZN . ? A ZN 1047 ? 1_555 O13 ? D SWA . ? A SWA 1048 ? 1_555 73.0 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2008-01-08 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal CNS 1.1 ? package 'Axel T. Brunger' axel.brunger@yale.edu refinement http://cns.csb.yale.edu/v1.1/ Fortran_77 ? 1 PDB_EXTRACT 2.000 'April. 3, 2006' package PDB sw-help@rcsb.rutgers.edu 'data extraction' http://pdb.rutgers.edu/software/ C++ ? 2 ADSC Quantum ? ? ? ? 'data collection' ? ? ? 3 DENZO . ? ? ? ? 'data reduction' ? ? ? 4 SCALEPACK . ? ? ? ? 'data scaling' ? ? ? 5 CNS . ? ? ? ? phasing ? ? ? 6 # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 CB A ASN 155 ? B CA A ASN 155 ? ? C A ASN 155 ? ? 126.30 110.40 15.90 2.00 N 2 1 CA A MET 264 ? ? CB A MET 264 ? ? CG A MET 264 ? B 103.06 113.30 -10.24 1.70 N 3 1 CB A SER 677 ? A CA A SER 677 ? ? C A SER 677 ? ? 124.70 110.10 14.60 1.90 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 HIS A 79 ? ? -153.87 84.80 2 1 TRP A 95 ? ? -170.08 -87.02 3 1 ASP A 106 ? ? -131.17 -59.41 4 1 THR A 162 ? ? 61.79 -62.92 5 1 GLN A 227 ? ? -136.25 -47.45 6 1 ASP A 340 ? ? -170.29 -169.61 7 1 SER A 411 ? ? 50.44 -127.71 8 1 ILE A 549 ? ? -141.88 -50.38 9 1 LEU A 550 ? ? -168.49 118.49 10 1 PRO A 562 ? ? -81.78 38.98 11 1 ASN A 732 ? ? -91.67 57.55 12 1 SER A 762 ? ? 69.85 -2.92 13 1 SER A 833 ? ? -149.60 -15.44 14 1 ASP A 839 ? ? -123.24 -160.63 15 1 GLU A 991 ? ? 19.04 109.40 16 1 GLU A 992 ? ? -133.66 -135.74 17 1 HIS A 993 ? ? -30.64 108.76 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 30 1 Y 1 A GLN 30 ? A GLN 30 31 1 Y 1 A SER 1045 ? A SER 1045 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL SWA 5 '(4R)-2-METHYLPENTANE-2,4-DIOL' MRD 6 water HOH #