data_3B9F
# 
_entry.id   3B9F 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.292 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
PDB   3B9F         
RCSB  RCSB045244   
WWPDB D_1000045244 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.db_id 
_pdbx_database_related.details 
_pdbx_database_related.content_type 
PDB 2OL2 'native PCI' unspecified 
PDB 2HI9 'native PCI' unspecified 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.entry_id                        3B9F 
_pdbx_database_status.recvd_initial_deposition_date   2007-11-05 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.SG_entry                        ? 
_pdbx_database_status.pdb_format_compatible           Y 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.methods_development_category    ? 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
'Li, W.'           1 
'Adams, T.E.'      2 
'Huntington, J.A.' 3 
# 
_citation.id                        primary 
_citation.title                     
'Molecular basis of thrombin recognition by protein C inhibitor revealed by the 1.6-A structure of the heparin-bridged complex.' 
_citation.journal_abbrev            Proc.Natl.Acad.Sci.Usa 
_citation.journal_volume            105 
_citation.page_first                4661 
_citation.page_last                 4666 
_citation.year                      2008 
_citation.journal_id_ASTM           PNASA6 
_citation.country                   US 
_citation.journal_id_ISSN           0027-8424 
_citation.journal_id_CSD            0040 
_citation.book_publisher            ? 
_citation.pdbx_database_id_PubMed   18362344 
_citation.pdbx_database_id_DOI      10.1073/pnas.0711055105 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
primary 'Li, W.'           1 
primary 'Adams, T.E.'      2 
primary 'Nangalia, J.'     3 
primary 'Esmon, C.T.'      4 
primary 'Huntington, J.A.' 5 
# 
_cell.entry_id           3B9F 
_cell.length_a           44.055 
_cell.length_b           48.825 
_cell.length_c           97.850 
_cell.angle_alpha        78.72 
_cell.angle_beta         81.52 
_cell.angle_gamma        77.69 
_cell.Z_PDB              1 
_cell.pdbx_unique_axis   ? 
_cell.length_a_esd       ? 
_cell.length_b_esd       ? 
_cell.length_c_esd       ? 
_cell.angle_alpha_esd    ? 
_cell.angle_beta_esd     ? 
_cell.angle_gamma_esd    ? 
# 
_symmetry.entry_id                         3B9F 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1  polymer     man Prothrombin                             5641.175  1   3.4.21.5 ?                                
'Thrombin light chain' ? 
2  polymer     man Prothrombin                             29764.219 1   3.4.21.5 'S195A (chymotrypsin numbering)' 
'Thrombin heavy chain' ? 
3  polymer     man 'Plasma serine protease inhibitor'      44529.680 1   ?        ?                                ? ? 
4  non-polymer man N-ACETYL-D-GLUCOSAMINE                  221.208   1   ?        ?                                ? ? 
5  non-polymer man ALPHA-L-FUCOSE                          164.156   1   ?        ?                                ? ? 
6  non-polymer man N,O6-DISULFO-GLUCOSAMINE                339.298   1   ?        ?                                ? ? 
7  non-polymer man '2-O-sulfo-alpha-L-idopyranuronic acid' 274.203   1   ?        ?                                ? ? 
8  non-polymer syn 'SULFATE ION'                           96.063    3   ?        ?                                ? ? 
9  non-polymer syn GLYCEROL                                92.094    5   ?        ?                                ? ? 
10 water       nat water                                   18.015    523 ?        ?                                ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Coagulation factor II'                                                                                         
2 'Coagulation factor II'                                                                                         
3 'Protein C inhibitor, Acrosomal serine protease inhibitor,Plasminogen activator inhibitor 3,PAI3,PCI,Serpin A5' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no TATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR TATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR L ? 
2 'polypeptide(L)' no no 
;IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISM
LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL
QVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFY
THVFRLKKWIQKVIDQFGE
;
;IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISM
LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL
QVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFY
THVFRLKKWIQKVIDQFGE
;
H ? 
3 'polypeptide(L)' no no 
;MGHHHHHHHHHHSSGHIDDDDKHMVGATVAPSSRRDFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQI
LEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQ
INDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLS
CRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHA
DLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP
;
;MGHHHHHHHHHHSSGHIDDDDKHMVGATVAPSSRRDFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQI
LEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQ
INDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLS
CRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHA
DLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP
;
I ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   THR n 
1 2   ALA n 
1 3   THR n 
1 4   SER n 
1 5   GLU n 
1 6   TYR n 
1 7   GLN n 
1 8   THR n 
1 9   PHE n 
1 10  PHE n 
1 11  ASN n 
1 12  PRO n 
1 13  ARG n 
1 14  THR n 
1 15  PHE n 
1 16  GLY n 
1 17  SER n 
1 18  GLY n 
1 19  GLU n 
1 20  ALA n 
1 21  ASP n 
1 22  CYS n 
1 23  GLY n 
1 24  LEU n 
1 25  ARG n 
1 26  PRO n 
1 27  LEU n 
1 28  PHE n 
1 29  GLU n 
1 30  LYS n 
1 31  LYS n 
1 32  SER n 
1 33  LEU n 
1 34  GLU n 
1 35  ASP n 
1 36  LYS n 
1 37  THR n 
1 38  GLU n 
1 39  ARG n 
1 40  GLU n 
1 41  LEU n 
1 42  LEU n 
1 43  GLU n 
1 44  SER n 
1 45  TYR n 
1 46  ILE n 
1 47  ASP n 
1 48  GLY n 
1 49  ARG n 
2 1   ILE n 
2 2   VAL n 
2 3   GLU n 
2 4   GLY n 
2 5   SER n 
2 6   ASP n 
2 7   ALA n 
2 8   GLU n 
2 9   ILE n 
2 10  GLY n 
2 11  MET n 
2 12  SER n 
2 13  PRO n 
2 14  TRP n 
2 15  GLN n 
2 16  VAL n 
2 17  MET n 
2 18  LEU n 
2 19  PHE n 
2 20  ARG n 
2 21  LYS n 
2 22  SER n 
2 23  PRO n 
2 24  GLN n 
2 25  GLU n 
2 26  LEU n 
2 27  LEU n 
2 28  CYS n 
2 29  GLY n 
2 30  ALA n 
2 31  SER n 
2 32  LEU n 
2 33  ILE n 
2 34  SER n 
2 35  ASP n 
2 36  ARG n 
2 37  TRP n 
2 38  VAL n 
2 39  LEU n 
2 40  THR n 
2 41  ALA n 
2 42  ALA n 
2 43  HIS n 
2 44  CYS n 
2 45  LEU n 
2 46  LEU n 
2 47  TYR n 
2 48  PRO n 
2 49  PRO n 
2 50  TRP n 
2 51  ASP n 
2 52  LYS n 
2 53  ASN n 
2 54  PHE n 
2 55  THR n 
2 56  GLU n 
2 57  ASN n 
2 58  ASP n 
2 59  LEU n 
2 60  LEU n 
2 61  VAL n 
2 62  ARG n 
2 63  ILE n 
2 64  GLY n 
2 65  LYS n 
2 66  HIS n 
2 67  SER n 
2 68  ARG n 
2 69  THR n 
2 70  ARG n 
2 71  TYR n 
2 72  GLU n 
2 73  ARG n 
2 74  ASN n 
2 75  ILE n 
2 76  GLU n 
2 77  LYS n 
2 78  ILE n 
2 79  SER n 
2 80  MET n 
2 81  LEU n 
2 82  GLU n 
2 83  LYS n 
2 84  ILE n 
2 85  TYR n 
2 86  ILE n 
2 87  HIS n 
2 88  PRO n 
2 89  ARG n 
2 90  TYR n 
2 91  ASN n 
2 92  TRP n 
2 93  ARG n 
2 94  GLU n 
2 95  ASN n 
2 96  LEU n 
2 97  ASP n 
2 98  ARG n 
2 99  ASP n 
2 100 ILE n 
2 101 ALA n 
2 102 LEU n 
2 103 MET n 
2 104 LYS n 
2 105 LEU n 
2 106 LYS n 
2 107 LYS n 
2 108 PRO n 
2 109 VAL n 
2 110 ALA n 
2 111 PHE n 
2 112 SER n 
2 113 ASP n 
2 114 TYR n 
2 115 ILE n 
2 116 HIS n 
2 117 PRO n 
2 118 VAL n 
2 119 CYS n 
2 120 LEU n 
2 121 PRO n 
2 122 ASP n 
2 123 ARG n 
2 124 GLU n 
2 125 THR n 
2 126 ALA n 
2 127 ALA n 
2 128 SER n 
2 129 LEU n 
2 130 LEU n 
2 131 GLN n 
2 132 ALA n 
2 133 GLY n 
2 134 TYR n 
2 135 LYS n 
2 136 GLY n 
2 137 ARG n 
2 138 VAL n 
2 139 THR n 
2 140 GLY n 
2 141 TRP n 
2 142 GLY n 
2 143 ASN n 
2 144 LEU n 
2 145 LYS n 
2 146 GLU n 
2 147 THR n 
2 148 TRP n 
2 149 THR n 
2 150 ALA n 
2 151 ASN n 
2 152 VAL n 
2 153 GLY n 
2 154 LYS n 
2 155 GLY n 
2 156 GLN n 
2 157 PRO n 
2 158 SER n 
2 159 VAL n 
2 160 LEU n 
2 161 GLN n 
2 162 VAL n 
2 163 VAL n 
2 164 ASN n 
2 165 LEU n 
2 166 PRO n 
2 167 ILE n 
2 168 VAL n 
2 169 GLU n 
2 170 ARG n 
2 171 PRO n 
2 172 VAL n 
2 173 CYS n 
2 174 LYS n 
2 175 ASP n 
2 176 SER n 
2 177 THR n 
2 178 ARG n 
2 179 ILE n 
2 180 ARG n 
2 181 ILE n 
2 182 THR n 
2 183 ASP n 
2 184 ASN n 
2 185 MET n 
2 186 PHE n 
2 187 CYS n 
2 188 ALA n 
2 189 GLY n 
2 190 TYR n 
2 191 LYS n 
2 192 PRO n 
2 193 ASP n 
2 194 GLU n 
2 195 GLY n 
2 196 LYS n 
2 197 ARG n 
2 198 GLY n 
2 199 ASP n 
2 200 ALA n 
2 201 CYS n 
2 202 GLU n 
2 203 GLY n 
2 204 ASP n 
2 205 ALA n 
2 206 GLY n 
2 207 GLY n 
2 208 PRO n 
2 209 PHE n 
2 210 VAL n 
2 211 MET n 
2 212 LYS n 
2 213 SER n 
2 214 PRO n 
2 215 PHE n 
2 216 ASN n 
2 217 ASN n 
2 218 ARG n 
2 219 TRP n 
2 220 TYR n 
2 221 GLN n 
2 222 MET n 
2 223 GLY n 
2 224 ILE n 
2 225 VAL n 
2 226 SER n 
2 227 TRP n 
2 228 GLY n 
2 229 GLU n 
2 230 GLY n 
2 231 CYS n 
2 232 ASP n 
2 233 ARG n 
2 234 ASP n 
2 235 GLY n 
2 236 LYS n 
2 237 TYR n 
2 238 GLY n 
2 239 PHE n 
2 240 TYR n 
2 241 THR n 
2 242 HIS n 
2 243 VAL n 
2 244 PHE n 
2 245 ARG n 
2 246 LEU n 
2 247 LYS n 
2 248 LYS n 
2 249 TRP n 
2 250 ILE n 
2 251 GLN n 
2 252 LYS n 
2 253 VAL n 
2 254 ILE n 
2 255 ASP n 
2 256 GLN n 
2 257 PHE n 
2 258 GLY n 
2 259 GLU n 
3 1   MET n 
3 2   GLY n 
3 3   HIS n 
3 4   HIS n 
3 5   HIS n 
3 6   HIS n 
3 7   HIS n 
3 8   HIS n 
3 9   HIS n 
3 10  HIS n 
3 11  HIS n 
3 12  HIS n 
3 13  SER n 
3 14  SER n 
3 15  GLY n 
3 16  HIS n 
3 17  ILE n 
3 18  ASP n 
3 19  ASP n 
3 20  ASP n 
3 21  ASP n 
3 22  LYS n 
3 23  HIS n 
3 24  MET n 
3 25  VAL n 
3 26  GLY n 
3 27  ALA n 
3 28  THR n 
3 29  VAL n 
3 30  ALA n 
3 31  PRO n 
3 32  SER n 
3 33  SER n 
3 34  ARG n 
3 35  ARG n 
3 36  ASP n 
3 37  PHE n 
3 38  THR n 
3 39  PHE n 
3 40  ASP n 
3 41  LEU n 
3 42  TYR n 
3 43  ARG n 
3 44  ALA n 
3 45  LEU n 
3 46  ALA n 
3 47  SER n 
3 48  ALA n 
3 49  ALA n 
3 50  PRO n 
3 51  SER n 
3 52  GLN n 
3 53  ASN n 
3 54  ILE n 
3 55  PHE n 
3 56  PHE n 
3 57  SER n 
3 58  PRO n 
3 59  VAL n 
3 60  SER n 
3 61  ILE n 
3 62  SER n 
3 63  MET n 
3 64  SER n 
3 65  LEU n 
3 66  ALA n 
3 67  MET n 
3 68  LEU n 
3 69  SER n 
3 70  LEU n 
3 71  GLY n 
3 72  ALA n 
3 73  GLY n 
3 74  SER n 
3 75  SER n 
3 76  THR n 
3 77  LYS n 
3 78  MET n 
3 79  GLN n 
3 80  ILE n 
3 81  LEU n 
3 82  GLU n 
3 83  GLY n 
3 84  LEU n 
3 85  GLY n 
3 86  LEU n 
3 87  ASN n 
3 88  LEU n 
3 89  GLN n 
3 90  LYS n 
3 91  SER n 
3 92  SER n 
3 93  GLU n 
3 94  LYS n 
3 95  GLU n 
3 96  LEU n 
3 97  HIS n 
3 98  ARG n 
3 99  GLY n 
3 100 PHE n 
3 101 GLN n 
3 102 GLN n 
3 103 LEU n 
3 104 LEU n 
3 105 GLN n 
3 106 GLU n 
3 107 LEU n 
3 108 ASN n 
3 109 GLN n 
3 110 PRO n 
3 111 ARG n 
3 112 ASP n 
3 113 GLY n 
3 114 PHE n 
3 115 GLN n 
3 116 LEU n 
3 117 SER n 
3 118 LEU n 
3 119 GLY n 
3 120 ASN n 
3 121 ALA n 
3 122 LEU n 
3 123 PHE n 
3 124 THR n 
3 125 ASP n 
3 126 LEU n 
3 127 VAL n 
3 128 VAL n 
3 129 ASP n 
3 130 LEU n 
3 131 GLN n 
3 132 ASP n 
3 133 THR n 
3 134 PHE n 
3 135 VAL n 
3 136 SER n 
3 137 ALA n 
3 138 MET n 
3 139 LYS n 
3 140 THR n 
3 141 LEU n 
3 142 TYR n 
3 143 LEU n 
3 144 ALA n 
3 145 ASP n 
3 146 THR n 
3 147 PHE n 
3 148 PRO n 
3 149 THR n 
3 150 ASN n 
3 151 PHE n 
3 152 ARG n 
3 153 ASP n 
3 154 SER n 
3 155 ALA n 
3 156 GLY n 
3 157 ALA n 
3 158 MET n 
3 159 LYS n 
3 160 GLN n 
3 161 ILE n 
3 162 ASN n 
3 163 ASP n 
3 164 TYR n 
3 165 VAL n 
3 166 ALA n 
3 167 LYS n 
3 168 GLN n 
3 169 THR n 
3 170 LYS n 
3 171 GLY n 
3 172 LYS n 
3 173 ILE n 
3 174 VAL n 
3 175 ASP n 
3 176 LEU n 
3 177 LEU n 
3 178 LYS n 
3 179 ASN n 
3 180 LEU n 
3 181 ASP n 
3 182 SER n 
3 183 ASN n 
3 184 ALA n 
3 185 VAL n 
3 186 VAL n 
3 187 ILE n 
3 188 MET n 
3 189 VAL n 
3 190 ASN n 
3 191 TYR n 
3 192 ILE n 
3 193 PHE n 
3 194 PHE n 
3 195 LYS n 
3 196 ALA n 
3 197 LYS n 
3 198 TRP n 
3 199 GLU n 
3 200 THR n 
3 201 SER n 
3 202 PHE n 
3 203 ASN n 
3 204 HIS n 
3 205 LYS n 
3 206 GLY n 
3 207 THR n 
3 208 GLN n 
3 209 GLU n 
3 210 GLN n 
3 211 ASP n 
3 212 PHE n 
3 213 TYR n 
3 214 VAL n 
3 215 THR n 
3 216 SER n 
3 217 GLU n 
3 218 THR n 
3 219 VAL n 
3 220 VAL n 
3 221 ARG n 
3 222 VAL n 
3 223 PRO n 
3 224 MET n 
3 225 MET n 
3 226 SER n 
3 227 ARG n 
3 228 GLU n 
3 229 ASP n 
3 230 GLN n 
3 231 TYR n 
3 232 HIS n 
3 233 TYR n 
3 234 LEU n 
3 235 LEU n 
3 236 ASP n 
3 237 ARG n 
3 238 ASN n 
3 239 LEU n 
3 240 SER n 
3 241 CYS n 
3 242 ARG n 
3 243 VAL n 
3 244 VAL n 
3 245 GLY n 
3 246 VAL n 
3 247 PRO n 
3 248 TYR n 
3 249 GLN n 
3 250 GLY n 
3 251 ASN n 
3 252 ALA n 
3 253 THR n 
3 254 ALA n 
3 255 LEU n 
3 256 PHE n 
3 257 ILE n 
3 258 LEU n 
3 259 PRO n 
3 260 SER n 
3 261 GLU n 
3 262 GLY n 
3 263 LYS n 
3 264 MET n 
3 265 GLN n 
3 266 GLN n 
3 267 VAL n 
3 268 GLU n 
3 269 ASN n 
3 270 GLY n 
3 271 LEU n 
3 272 SER n 
3 273 GLU n 
3 274 LYS n 
3 275 THR n 
3 276 LEU n 
3 277 ARG n 
3 278 LYS n 
3 279 TRP n 
3 280 LEU n 
3 281 LYS n 
3 282 MET n 
3 283 PHE n 
3 284 LYS n 
3 285 LYS n 
3 286 ARG n 
3 287 GLN n 
3 288 LEU n 
3 289 GLU n 
3 290 LEU n 
3 291 TYR n 
3 292 LEU n 
3 293 PRO n 
3 294 LYS n 
3 295 PHE n 
3 296 SER n 
3 297 ILE n 
3 298 GLU n 
3 299 GLY n 
3 300 SER n 
3 301 TYR n 
3 302 GLN n 
3 303 LEU n 
3 304 GLU n 
3 305 LYS n 
3 306 VAL n 
3 307 LEU n 
3 308 PRO n 
3 309 SER n 
3 310 LEU n 
3 311 GLY n 
3 312 ILE n 
3 313 SER n 
3 314 ASN n 
3 315 VAL n 
3 316 PHE n 
3 317 THR n 
3 318 SER n 
3 319 HIS n 
3 320 ALA n 
3 321 ASP n 
3 322 LEU n 
3 323 SER n 
3 324 GLY n 
3 325 ILE n 
3 326 SER n 
3 327 ASN n 
3 328 HIS n 
3 329 SER n 
3 330 ASN n 
3 331 ILE n 
3 332 GLN n 
3 333 VAL n 
3 334 SER n 
3 335 GLU n 
3 336 MET n 
3 337 VAL n 
3 338 HIS n 
3 339 LYS n 
3 340 ALA n 
3 341 VAL n 
3 342 VAL n 
3 343 GLU n 
3 344 VAL n 
3 345 ASP n 
3 346 GLU n 
3 347 SER n 
3 348 GLY n 
3 349 THR n 
3 350 ARG n 
3 351 ALA n 
3 352 ALA n 
3 353 ALA n 
3 354 ALA n 
3 355 THR n 
3 356 GLY n 
3 357 THR n 
3 358 ILE n 
3 359 PHE n 
3 360 THR n 
3 361 PHE n 
3 362 ARG n 
3 363 SER n 
3 364 ALA n 
3 365 ARG n 
3 366 LEU n 
3 367 ASN n 
3 368 SER n 
3 369 GLN n 
3 370 ARG n 
3 371 LEU n 
3 372 VAL n 
3 373 PHE n 
3 374 ASN n 
3 375 ARG n 
3 376 PRO n 
3 377 PHE n 
3 378 LEU n 
3 379 MET n 
3 380 PHE n 
3 381 ILE n 
3 382 VAL n 
3 383 ASP n 
3 384 ASN n 
3 385 ASN n 
3 386 ILE n 
3 387 LEU n 
3 388 PHE n 
3 389 LEU n 
3 390 GLY n 
3 391 LYS n 
3 392 VAL n 
3 393 ASN n 
3 394 ARG n 
3 395 PRO n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 49  Human Homo F2                             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 Escherichia ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 259 Human Homo F2                             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 Escherichia ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 395 Human ?    'SERPINA5, PCI, PLANH3, PROCI' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562 ?           ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP THRB_HUMAN P00734 ? 1 TATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGR 315 
2 UNP THRB_HUMAN P00734 ? 2 
;IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISM
LEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVL
QVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFY
THVFRLKKWIQKVIDQFGE
;
364 
3 UNP IPSP_HUMAN P05154 ? 3 
;VGATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLL
QELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNA
VVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKM
QQVENGLSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV
DESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP
;
36  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 3B9F L 1  ? 49  ? P00734 315 ? 363 ? -2 16  
2 2 3B9F H 1  ? 259 ? P00734 364 ? 622 ? 16 247 
3 3 3B9F I 25 ? 395 ? P05154 36  ? 406 ? 17 387 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 3B9F ALA H 205 ? UNP P00734 SER 568 'engineered mutation'  195 1  
3 3B9F MET I 1   ? UNP P05154 ?   ?   'expression tag'       -7  2  
3 3B9F GLY I 2   ? UNP P05154 ?   ?   'expression tag'       -6  3  
3 3B9F HIS I 3   ? UNP P05154 ?   ?   'expression tag'       -5  4  
3 3B9F HIS I 4   ? UNP P05154 ?   ?   'expression tag'       -4  5  
3 3B9F HIS I 5   ? UNP P05154 ?   ?   'expression tag'       -3  6  
3 3B9F HIS I 6   ? UNP P05154 ?   ?   'expression tag'       -2  7  
3 3B9F HIS I 7   ? UNP P05154 ?   ?   'expression tag'       -1  8  
3 3B9F HIS I 8   ? UNP P05154 ?   ?   'expression tag'       0   9  
3 3B9F HIS I 9   ? UNP P05154 ?   ?   'expression tag'       1   10 
3 3B9F HIS I 10  ? UNP P05154 ?   ?   'expression tag'       2   11 
3 3B9F HIS I 11  ? UNP P05154 ?   ?   'expression tag'       3   12 
3 3B9F HIS I 12  ? UNP P05154 ?   ?   'expression tag'       4   13 
3 3B9F SER I 13  ? UNP P05154 ?   ?   'expression tag'       5   14 
3 3B9F SER I 14  ? UNP P05154 ?   ?   'expression tag'       6   15 
3 3B9F GLY I 15  ? UNP P05154 ?   ?   'expression tag'       7   16 
3 3B9F HIS I 16  ? UNP P05154 ?   ?   'expression tag'       8   17 
3 3B9F ILE I 17  ? UNP P05154 ?   ?   'expression tag'       9   18 
3 3B9F ASP I 18  ? UNP P05154 ?   ?   'expression tag'       10  19 
3 3B9F ASP I 19  ? UNP P05154 ?   ?   'expression tag'       11  20 
3 3B9F ASP I 20  ? UNP P05154 ?   ?   'expression tag'       12  21 
3 3B9F ASP I 21  ? UNP P05154 ?   ?   'expression tag'       13  22 
3 3B9F LYS I 22  ? UNP P05154 ?   ?   'expression tag'       14  23 
3 3B9F HIS I 23  ? UNP P05154 ?   ?   'expression tag'       15  24 
3 3B9F MET I 24  ? UNP P05154 ?   ?   'expression tag'       16  25 
3 3B9F ASN I 53  ? UNP P05154 SER 64  'see sequence details' 45  26 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                 ?                               'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                                ?                               'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                              ?                               'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                         ?                               'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                                ?                               'C3 H7 N O2 S'    121.158 
FUC saccharide          . ALPHA-L-FUCOSE                          ?                               'C6 H12 O5'       164.156 
GLN 'L-peptide linking' y GLUTAMINE                               ?                               'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                         ?                               'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                                 ?                               'C2 H5 N O2'      75.067  
GOL non-polymer         . GLYCEROL                                'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'        92.094  
HIS 'L-peptide linking' y HISTIDINE                               ?                               'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                   ?                               'H2 O'            18.015  
IDS saccharide          . '2-O-sulfo-alpha-L-idopyranuronic acid' 'O2-SULFO-GLUCURONIC ACID'      'C6 H10 O10 S'    274.203 
ILE 'L-peptide linking' y ISOLEUCINE                              ?                               'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                                 ?                               'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                                  ?                               'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                              ?                               'C5 H11 N O2 S'   149.211 
NAG D-saccharide        . N-ACETYL-D-GLUCOSAMINE                  ?                               'C8 H15 N O6'     221.208 
PHE 'L-peptide linking' y PHENYLALANINE                           ?                               'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                                 ?                               'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                                  ?                               'C3 H7 N O3'      105.093 
SGN saccharide          . N,O6-DISULFO-GLUCOSAMINE                ?                               'C6 H13 N O11 S2' 339.298 
SO4 non-polymer         . 'SULFATE ION'                           ?                               'O4 S -2'         96.063  
THR 'L-peptide linking' y THREONINE                               ?                               'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                              ?                               'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                                ?                               'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                                  ?                               'C5 H11 N O2'     117.146 
# 
_exptl.entry_id          3B9F 
_exptl.method            'X-RAY DIFFRACTION' 
_exptl.crystals_number   1 
# 
_exptl_crystal.id                    1 
_exptl_crystal.density_meas          ? 
_exptl_crystal.density_Matthews      2.51 
_exptl_crystal.density_percent_sol   50.95 
_exptl_crystal.description           ? 
_exptl_crystal.F_000                 ? 
_exptl_crystal.preparation           ? 
# 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.temp            295 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.pH              7.4 
_exptl_crystal_grow.pdbx_details    '11% PEG 3350, 0.12M MgSO4, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 295K' 
_exptl_crystal_grow.pdbx_pH_range   . 
# 
_diffrn.id                     1 
_diffrn.ambient_temp           100 
_diffrn.ambient_temp_details   ? 
_diffrn.crystal_id             1 
# 
_diffrn_detector.diffrn_id              1 
_diffrn_detector.detector               CCD 
_diffrn_detector.type                   'ADSC QUANTUM 4' 
_diffrn_detector.pdbx_collection_date   2007-08-02 
_diffrn_detector.details                ? 
# 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.monochromator                    'Si (111) double crystal monochromator' 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.06 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.diffrn_id                   1 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.type                        'DIAMOND BEAMLINE I03' 
_diffrn_source.pdbx_synchrotron_site       Diamond 
_diffrn_source.pdbx_synchrotron_beamline   I03 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_wavelength_list        1.06 
# 
_reflns.entry_id                     3B9F 
_reflns.observed_criterion_sigma_I   0 
_reflns.observed_criterion_sigma_F   0 
_reflns.d_resolution_low             37.50 
_reflns.d_resolution_high            1.60 
_reflns.number_obs                   95914 
_reflns.number_all                   102472 
_reflns.percent_possible_obs         93.6 
_reflns.pdbx_Rmerge_I_obs            0.052 
_reflns.pdbx_Rsym_value              0.052 
_reflns.pdbx_netI_over_sigmaI        9.1 
_reflns.B_iso_Wilson_estimate        20.4 
_reflns.pdbx_redundancy              3.2 
_reflns.R_free_details               ? 
_reflns.limit_h_max                  ? 
_reflns.limit_h_min                  ? 
_reflns.limit_k_max                  ? 
_reflns.limit_k_min                  ? 
_reflns.limit_l_max                  ? 
_reflns.limit_l_min                  ? 
_reflns.observed_criterion_F_max     ? 
_reflns.observed_criterion_F_min     ? 
_reflns.pdbx_chi_squared             ? 
_reflns.pdbx_scaling_rejects         ? 
_reflns.pdbx_ordinal                 1 
_reflns.pdbx_diffrn_id               1 
# 
_reflns_shell.d_res_high             1.60 
_reflns_shell.d_res_low              1.69 
_reflns_shell.percent_possible_all   90.3 
_reflns_shell.Rmerge_I_obs           0.445 
_reflns_shell.pdbx_Rsym_value        0.445 
_reflns_shell.meanI_over_sigI_obs    1.8 
_reflns_shell.pdbx_redundancy        1.9 
_reflns_shell.percent_possible_obs   ? 
_reflns_shell.number_unique_all      13603 
_reflns_shell.number_measured_all    ? 
_reflns_shell.number_measured_obs    ? 
_reflns_shell.number_unique_obs      ? 
_reflns_shell.pdbx_chi_squared       ? 
_reflns_shell.pdbx_ordinal           1 
_reflns_shell.pdbx_diffrn_id         1 
# 
_refine.entry_id                                 3B9F 
_refine.ls_number_reflns_obs                     95905 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          .0 
_refine.pdbx_data_cutoff_high_absF               1049755.16 
_refine.pdbx_data_cutoff_low_absF                .000000 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             30.95 
_refine.ls_d_res_high                            1.60 
_refine.ls_percent_reflns_obs                    93.4 
_refine.ls_R_factor_obs                          0.208 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       0.208 
_refine.ls_R_factor_R_free                       0.234 
_refine.ls_R_factor_R_free_error                 .004 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 3.1 
_refine.ls_number_reflns_R_free                  2928 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               30.2 
_refine.aniso_B[1][1]                            1.76 
_refine.aniso_B[2][2]                            -.68 
_refine.aniso_B[3][3]                            -1.08 
_refine.aniso_B[1][2]                            -1.98 
_refine.aniso_B[1][3]                            -2.66 
_refine.aniso_B[2][3]                            4.78 
_refine.solvent_model_details                    'FLAT MODEL' 
_refine.solvent_model_param_ksol                 .358332 
_refine.solvent_model_param_bsol                 53.1506 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.details                                  ? 
_refine.pdbx_starting_model                      2OL2 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_isotropic_thermal_model             RESTRAINED 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_B                             ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.B_iso_min                                ? 
_refine.B_iso_max                                ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.pdbx_diffrn_id                           1 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
_refine_analyze.entry_id                        3B9F 
_refine_analyze.Luzzati_coordinate_error_obs    .21 
_refine_analyze.Luzzati_sigma_a_obs             .24 
_refine_analyze.Luzzati_d_res_low_obs           5.00 
_refine_analyze.Luzzati_coordinate_error_free   .23 
_refine_analyze.Luzzati_sigma_a_free            .24 
_refine_analyze.Luzzati_d_res_low_free          ? 
_refine_analyze.number_disordered_residues      ? 
_refine_analyze.occupancy_sum_hydrogen          ? 
_refine_analyze.occupancy_sum_non_hydrogen      ? 
_refine_analyze.pdbx_Luzzati_d_res_high_obs     ? 
_refine_analyze.pdbx_refine_id                  'X-RAY DIFFRACTION' 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        5113 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         100 
_refine_hist.number_atoms_solvent             523 
_refine_hist.number_atoms_total               5736 
_refine_hist.d_res_high                       1.60 
_refine_hist.d_res_low                        30.95 
# 
loop_
_refine_ls_restr.type 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.weight 
_refine_ls_restr.number 
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.pdbx_restraint_function 
c_bond_d           .005 ?    ? ? 'X-RAY DIFFRACTION' ? 
c_angle_deg        1.3  ?    ? ? 'X-RAY DIFFRACTION' ? 
c_dihedral_angle_d 23.8 ?    ? ? 'X-RAY DIFFRACTION' ? 
c_improper_angle_d .74  ?    ? ? 'X-RAY DIFFRACTION' ? 
c_mcbond_it        1.21 1.50 ? ? 'X-RAY DIFFRACTION' ? 
c_mcangle_it       1.93 2.00 ? ? 'X-RAY DIFFRACTION' ? 
c_scbond_it        1.58 2.00 ? ? 'X-RAY DIFFRACTION' ? 
c_scangle_it       2.39 2.50 ? ? 'X-RAY DIFFRACTION' ? 
# 
_refine_ls_shell.pdbx_total_number_of_bins_used   6 
_refine_ls_shell.d_res_high                       1.60 
_refine_ls_shell.d_res_low                        1.70 
_refine_ls_shell.number_reflns_R_work             15020 
_refine_ls_shell.R_factor_R_work                  0.325 
_refine_ls_shell.percent_reflns_obs               90.5 
_refine_ls_shell.R_factor_R_free                  0.337 
_refine_ls_shell.R_factor_R_free_error            .016 
_refine_ls_shell.percent_reflns_R_free            3.0 
_refine_ls_shell.number_reflns_R_free             460 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.number_reflns_obs                15480 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
# 
loop_
_pdbx_xplor_file.serial_no 
_pdbx_xplor_file.param_file 
_pdbx_xplor_file.topol_file 
_pdbx_xplor_file.pdbx_refine_id 
1 protein_rep.param  protein.top      'X-RAY DIFFRACTION' 
2 carbohydrate.param carbohydrate.top 'X-RAY DIFFRACTION' 
3 water_rep.param    water.top        'X-RAY DIFFRACTION' 
4 ion.param          ion.top          'X-RAY DIFFRACTION' 
5 ligand.param       ligand.top       'X-RAY DIFFRACTION' 
# 
_struct.entry_id                  3B9F 
_struct.title                     '1.6 A structure of the PCI-thrombin-heparin complex' 
_struct.pdbx_descriptor           'Prothrombin (E.C.3.4.21.5), protein C inhibitor' 
_struct.pdbx_model_details        ? 
_struct.pdbx_CASP_flag            ? 
_struct.pdbx_model_type_details   ? 
# 
_struct_keywords.entry_id        3B9F 
_struct_keywords.pdbx_keywords   'HYDROLASE/HYDROLASE INHIBITOR' 
_struct_keywords.text            
;Michaelis complex, Acute phase, Blood coagulation, Cleavage on pair of basic residues, Disease mutation, Gamma-carboxyglutamic acid, Glycoprotein, Hydrolase, Kringle, Protease, Secreted, Serine protease, Zymogen, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
;
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1  ? 
B N N 2  ? 
C N N 3  ? 
D N N 4  ? 
E N N 5  ? 
F N N 6  ? 
G N N 7  ? 
H N N 8  ? 
I N N 9  ? 
J N N 9  ? 
K N N 9  ? 
L N N 8  ? 
M N N 8  ? 
N N N 9  ? 
O N N 9  ? 
P N N 10 ? 
Q N N 10 ? 
R N N 10 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  1  ASN A 11  K GLY A 16  F ASN L 1   GLY L 1   1 ? 6  
HELX_P HELX_P2  2  PHE A 28  ? SER A 32  ? PHE L 7   SER L 11  5 ? 5  
HELX_P HELX_P3  3  THR A 37  B TYR A 45  J THR L 14  TYR L 14  1 ? 9  
HELX_P HELX_P4  4  ALA B 41  ? CYS B 44  ? ALA H 55  CYS H 58  5 ? 4  
HELX_P HELX_P5  5  PRO B 48  B ASP B 51  E PRO H 60  ASP H 60  5 ? 4  
HELX_P HELX_P6  6  THR B 55  I ASN B 57  ? THR H 60  ASN H 62  5 ? 3  
HELX_P HELX_P7  7  ASP B 122 ? LEU B 130 ? ASP H 125 LEU H 130 1 ? 9  
HELX_P HELX_P8  8  GLU B 169 ? SER B 176 ? GLU H 164 SER H 171 1 ? 8  
HELX_P HELX_P9  9  LEU B 246 ? GLY B 258 ? LEU H 234 GLY H 246 1 ? 13 
HELX_P HELX_P10 10 ASP C 36  ? ALA C 49  ? ASP I 28  ALA I 41  1 ? 14 
HELX_P HELX_P11 11 SER C 57  ? SER C 69  ? SER I 49  SER I 61  1 ? 13 
HELX_P HELX_P12 12 LEU C 70  ? ALA C 72  ? LEU I 62  ALA I 64  5 ? 3  
HELX_P HELX_P13 13 GLY C 73  ? LEU C 84  ? GLY I 65  LEU I 76  1 ? 12 
HELX_P HELX_P14 14 SER C 92  ? LEU C 107 ? SER I 84  LEU I 99  1 ? 16 
HELX_P HELX_P15 15 GLN C 131 ? LEU C 143 ? GLN I 123 LEU I 135 1 ? 13 
HELX_P HELX_P16 16 ASP C 153 ? THR C 169 ? ASP I 145 THR I 161 1 ? 17 
HELX_P HELX_P17 17 LYS C 263 ? LEU C 271 ? LYS I 255 LEU I 263 1 ? 9  
HELX_P HELX_P18 18 SER C 272 ? PHE C 283 ? SER I 264 PHE I 275 1 ? 12 
HELX_P HELX_P19 19 GLU C 304 ? GLY C 311 ? GLU I 296 GLY I 303 5 ? 8  
HELX_P HELX_P20 20 SER C 313 ? THR C 317 ? SER I 305 THR I 309 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
disulf1 disulf ? ? A CYS 22  SG  ? ? ? 1_555 B CYS 119 SG ? ? L CYS 1   H CYS 122 1_555 ? ? ? ? ? ? ? 2.029 ? 
disulf2 disulf ? ? B CYS 28  SG  ? ? ? 1_555 B CYS 44  SG ? ? H CYS 42  H CYS 58  1_555 ? ? ? ? ? ? ? 2.022 ? 
disulf3 disulf ? ? B CYS 173 SG  ? ? ? 1_555 B CYS 187 SG ? ? H CYS 168 H CYS 182 1_555 ? ? ? ? ? ? ? 2.031 ? 
disulf4 disulf ? ? B CYS 201 SG  ? ? ? 1_555 B CYS 231 SG ? ? H CYS 191 H CYS 220 1_555 ? ? ? ? ? ? ? 2.032 ? 
covale1 covale ? ? B ASN 53  ND2 ? G ? 1_555 D NAG .   C1 ? ? H ASN 60  H NAG 778 1_555 ? ? ? ? ? ? ? 1.451 ? 
covale2 covale ? ? D NAG .   O6  ? ? ? 1_555 E FUC .   C1 ? ? H NAG 778 H FUC 780 1_555 ? ? ? ? ? ? ? 1.400 ? 
covale3 covale ? ? F SGN .   C4  ? ? ? 1_555 G IDS .   O1 ? ? H SGN 1   H IDS 2   1_555 ? ? ? ? ? ? ? 1.436 ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 22  B . A SER 36  H PRO 23  B ? PRO 37  H 1 0.01 
2 LYS 191 B . ? LYS 185 H PRO 192 B ? PRO 186 H 1 0.28 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
A ? 7 ? 
B ? 7 ? 
C ? 2 ? 
D ? 7 ? 
E ? 8 ? 
F ? 5 ? 
G ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
A 1 2 ? anti-parallel 
A 2 3 ? anti-parallel 
A 3 4 ? anti-parallel 
A 4 5 ? anti-parallel 
A 5 6 ? anti-parallel 
A 6 7 ? anti-parallel 
B 1 2 ? anti-parallel 
B 2 3 ? anti-parallel 
B 3 4 ? anti-parallel 
B 4 5 ? anti-parallel 
B 5 6 ? anti-parallel 
B 6 7 ? anti-parallel 
C 1 2 ? anti-parallel 
D 1 2 ? anti-parallel 
D 2 3 ? anti-parallel 
D 3 4 ? anti-parallel 
D 4 5 ? anti-parallel 
D 5 6 ? anti-parallel 
D 6 7 ? anti-parallel 
E 1 2 ? anti-parallel 
E 2 3 ? anti-parallel 
E 3 4 ? anti-parallel 
E 4 5 ? anti-parallel 
E 5 6 ? anti-parallel 
E 6 7 ? anti-parallel 
E 7 8 ? parallel      
F 1 2 ? parallel      
F 2 3 ? anti-parallel 
F 3 4 ? parallel      
F 4 5 ? anti-parallel 
G 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
A 1 SER B 5   ? ASP B 6   ? SER H 20  ASP H 21  
A 2 GLN B 161 ? PRO B 166 ? GLN H 156 PRO H 161 
A 3 LYS B 135 ? GLY B 140 ? LYS H 135 GLY H 140 
A 4 PRO B 208 ? LYS B 212 ? PRO H 198 LYS H 202 
A 5 TRP B 219 ? VAL B 225 ? TRP H 207 VAL H 213 
A 6 GLY B 238 ? HIS B 242 ? GLY H 226 HIS H 230 
A 7 MET B 185 ? ALA B 188 ? MET H 180 ALA H 183 
B 1 LYS B 77  ? SER B 79  ? LYS H 81  SER H 83  
B 2 LEU B 59  ? ILE B 63  ? LEU H 64  ILE H 68  
B 3 GLN B 15  ? ARG B 20  ? GLN H 30  ARG H 35  
B 4 GLU B 25  ? LEU B 32  ? GLU H 39  LEU H 46  
B 5 TRP B 37  ? THR B 40  ? TRP H 51  THR H 54  
B 6 ALA B 101 ? LEU B 105 ? ALA H 104 LEU H 108 
B 7 LEU B 81  ? ILE B 86  ? LEU H 85  ILE H 90  
C 1 LEU B 46  ? TYR B 47  A LEU H 60  TYR H 60  
C 2 LYS B 52  F ASN B 53  G LYS H 60  ASN H 60  
D 1 ILE C 54  ? PHE C 56  ? ILE I 46  PHE I 48  
D 2 ILE C 386 ? VAL C 392 ? ILE I 378 VAL I 384 
D 3 PHE C 377 ? VAL C 382 ? PHE I 369 VAL I 374 
D 4 THR C 253 ? PRO C 259 ? THR I 245 PRO I 251 
D 5 CYS C 241 ? PRO C 247 ? CYS I 233 PRO I 239 
D 6 VAL C 219 ? ASP C 236 ? VAL I 211 ASP I 228 
D 7 GLN C 208 ? TYR C 213 ? GLN I 200 TYR I 205 
E 1 ILE C 54  ? PHE C 56  ? ILE I 46  PHE I 48  
E 2 ILE C 386 ? VAL C 392 ? ILE I 378 VAL I 384 
E 3 PHE C 377 ? VAL C 382 ? PHE I 369 VAL I 374 
E 4 THR C 253 ? PRO C 259 ? THR I 245 PRO I 251 
E 5 CYS C 241 ? PRO C 247 ? CYS I 233 PRO I 239 
E 6 VAL C 219 ? ASP C 236 ? VAL I 211 ASP I 228 
E 7 LYS C 284 ? PRO C 293 ? LYS I 276 PRO I 285 
E 8 GLN C 369 ? VAL C 372 ? GLN I 361 VAL I 364 
F 1 ASP C 145 ? THR C 149 ? ASP I 137 THR I 141 
F 2 LEU C 116 ? ASP C 125 ? LEU I 108 ASP I 117 
F 3 VAL C 186 ? PHE C 194 ? VAL I 178 PHE I 186 
F 4 GLU C 335 ? VAL C 344 ? GLU I 327 VAL I 336 
F 5 PHE C 295 ? GLN C 302 ? PHE I 287 GLN I 294 
G 1 TRP C 198 ? THR C 200 ? TRP I 190 THR I 192 
G 2 GLY C 348 ? ARG C 350 ? GLY I 340 ARG I 342 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
A 1 2 N SER B 5   ? N SER H 20  O VAL B 162 ? O VAL H 157 
A 2 3 O VAL B 163 ? O VAL H 158 N VAL B 138 ? N VAL H 138 
A 3 4 N ARG B 137 ? N ARG H 137 O VAL B 210 ? O VAL H 200 
A 4 5 N MET B 211 ? N MET H 201 O TYR B 220 ? O TYR H 208 
A 5 6 N ILE B 224 ? N ILE H 212 O THR B 241 ? O THR H 229 
A 6 7 O TYR B 240 ? O TYR H 228 N PHE B 186 ? N PHE H 181 
B 1 2 O LYS B 77  ? O LYS H 81  N ILE B 63  ? N ILE H 68  
B 2 3 O LEU B 60  ? O LEU H 65  N PHE B 19  ? N PHE H 34  
B 3 4 N LEU B 18  ? N LEU H 33  O LEU B 27  ? O LEU H 41  
B 4 5 N SER B 31  ? N SER H 45  O LEU B 39  ? O LEU H 53  
B 5 6 N VAL B 38  ? N VAL H 52  O MET B 103 ? O MET H 106 
B 6 7 O LEU B 102 ? O LEU H 105 N TYR B 85  ? N TYR H 89  
C 1 2 N TYR B 47  A N TYR H 60  O LYS B 52  F O LYS H 60  
D 1 2 N ILE C 54  ? N ILE I 46  O LYS C 391 ? O LYS I 383 
D 2 3 O VAL C 392 ? O VAL I 384 N PHE C 377 ? N PHE I 369 
D 3 4 O PHE C 380 ? O PHE I 372 N LEU C 255 ? N LEU I 247 
D 4 5 O ALA C 254 ? O ALA I 246 N VAL C 246 ? N VAL I 238 
D 5 6 O VAL C 243 ? O VAL I 235 N LEU C 234 ? N LEU I 226 
D 6 7 O VAL C 222 ? O VAL I 214 N GLN C 210 ? N GLN I 202 
E 1 2 N ILE C 54  ? N ILE I 46  O LYS C 391 ? O LYS I 383 
E 2 3 O VAL C 392 ? O VAL I 384 N PHE C 377 ? N PHE I 369 
E 3 4 O PHE C 380 ? O PHE I 372 N LEU C 255 ? N LEU I 247 
E 4 5 O ALA C 254 ? O ALA I 246 N VAL C 246 ? N VAL I 238 
E 5 6 O VAL C 243 ? O VAL I 235 N LEU C 234 ? N LEU I 226 
E 6 7 N ASP C 229 ? N ASP I 221 O LEU C 288 ? O LEU I 280 
E 7 8 N GLU C 289 ? N GLU I 281 O GLN C 369 ? O GLN I 361 
F 1 2 O THR C 149 ? O THR I 141 N THR C 124 ? N THR I 116 
F 2 3 N PHE C 123 ? N PHE I 115 O ILE C 187 ? O ILE I 179 
F 3 4 N ASN C 190 ? N ASN I 182 O VAL C 337 ? O VAL I 329 
F 4 5 O VAL C 344 ? O VAL I 336 N PHE C 295 ? N PHE I 287 
G 1 2 N TRP C 198 ? N TRP I 190 O THR C 349 ? O THR I 341 
# 
loop_
_struct_site.id 
_struct_site.pdbx_evidence_code 
_struct_site.pdbx_auth_asym_id 
_struct_site.pdbx_auth_comp_id 
_struct_site.pdbx_auth_seq_id 
_struct_site.pdbx_auth_ins_code 
_struct_site.pdbx_num_residues 
_struct_site.details 
AC1 Software ? ? ? ? 4  'BINDING SITE FOR RESIDUE NAG H 778' 
AC2 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE SGN H 1'   
AC3 Software ? ? ? ? 6  'BINDING SITE FOR RESIDUE IDS H 2'   
AC4 Software ? ? ? ? 4  'BINDING SITE FOR RESIDUE SO4 H 781' 
AC5 Software ? ? ? ? 3  'BINDING SITE FOR RESIDUE SO4 I 388' 
AC6 Software ? ? ? ? 5  'BINDING SITE FOR RESIDUE GOL H 782' 
AC7 Software ? ? ? ? 5  'BINDING SITE FOR RESIDUE GOL I 390' 
AC8 Software ? ? ? ? 8  'BINDING SITE FOR RESIDUE GOL H 3'   
AC9 Software ? ? ? ? 6  'BINDING SITE FOR RESIDUE GOL H 4'   
BC1 Software ? ? ? ? 3  'BINDING SITE FOR RESIDUE GOL I 391' 
# 
loop_
_struct_site_gen.id 
_struct_site_gen.site_id 
_struct_site_gen.pdbx_num_res 
_struct_site_gen.label_comp_id 
_struct_site_gen.label_asym_id 
_struct_site_gen.label_seq_id 
_struct_site_gen.pdbx_auth_ins_code 
_struct_site_gen.auth_comp_id 
_struct_site_gen.auth_asym_id 
_struct_site_gen.auth_seq_id 
_struct_site_gen.label_atom_id 
_struct_site_gen.label_alt_id 
_struct_site_gen.symmetry 
_struct_site_gen.details 
1  AC1 4  ASN B 53  G ASN H 60   . ? 1_555 ? 
2  AC1 4  HOH Q .   ? HOH H 1013 . ? 1_555 ? 
3  AC1 4  HOH Q .   ? HOH H 1014 . ? 1_555 ? 
4  AC1 4  HOH Q .   ? HOH H 1035 . ? 1_555 ? 
5  AC2 10 HIS B 87  ? HIS H 91   . ? 1_555 ? 
6  AC2 10 ARG B 89  ? ARG H 93   . ? 1_555 ? 
7  AC2 10 ARG B 98  ? ARG H 101  . ? 1_555 ? 
8  AC2 10 ASN B 184 ? ASN H 179  . ? 1_555 ? 
9  AC2 10 ARG B 245 ? ARG H 233  . ? 1_555 ? 
10 AC2 10 LEU B 246 ? LEU H 234  . ? 1_555 ? 
11 AC2 10 LYS B 248 ? LYS H 236  . ? 1_555 ? 
12 AC2 10 TRP B 249 ? TRP H 237  . ? 1_555 ? 
13 AC2 10 HOH Q .   ? HOH H 824  . ? 1_555 ? 
14 AC2 10 HOH Q .   ? HOH H 981  . ? 1_555 ? 
15 AC3 6  HIS B 87  ? HIS H 91   . ? 1_555 ? 
16 AC3 6  PRO B 88  ? PRO H 92   . ? 1_555 ? 
17 AC3 6  ARG B 89  ? ARG H 93   . ? 1_555 ? 
18 AC3 6  LYS B 248 ? LYS H 236  . ? 1_555 ? 
19 AC3 6  TRP B 249 ? TRP H 237  . ? 1_555 ? 
20 AC3 6  LYS B 252 ? LYS H 240  . ? 1_555 ? 
21 AC4 4  GLN B 24  ? GLN H 38   . ? 1_455 ? 
22 AC4 4  ARG B 170 ? ARG H 165  . ? 1_555 ? 
23 AC4 4  ASP B 183 ? ASP H 178  . ? 1_555 ? 
24 AC4 4  ARG B 245 ? ARG H 233  . ? 1_555 ? 
25 AC5 3  LYS B 174 ? LYS H 169  . ? 1_655 ? 
26 AC5 3  HOH Q .   ? HOH H 854  . ? 1_655 ? 
27 AC5 3  ARG C 370 ? ARG I 362  . ? 1_555 ? 
28 AC6 5  ARG B 170 ? ARG H 165  . ? 1_555 ? 
29 AC6 5  CYS B 173 ? CYS H 168  . ? 1_555 ? 
30 AC6 5  PHE B 186 ? PHE H 181  . ? 1_555 ? 
31 AC6 5  CYS B 187 ? CYS H 182  . ? 1_555 ? 
32 AC6 5  HOH Q .   ? HOH H 894  . ? 1_555 ? 
33 AC7 5  TRP B 50  D TRP H 60   . ? 1_555 ? 
34 AC7 5  THR C 357 ? THR I 349  . ? 1_555 ? 
35 AC7 5  THR C 360 ? THR I 352  . ? 1_555 ? 
36 AC7 5  PHE C 361 ? PHE I 353  . ? 1_555 ? 
37 AC7 5  HOH R .   ? HOH I 402  . ? 1_555 ? 
38 AC8 8  ARG B 70  ? ARG H 75   . ? 1_555 ? 
39 AC8 8  TYR B 71  ? TYR H 76   . ? 1_555 ? 
40 AC8 8  GLU B 72  ? GLU H 77   . ? 1_555 ? 
41 AC8 8  ARG B 73  A ARG H 77   . ? 1_555 ? 
42 AC8 8  GLN B 131 ? GLN H 131  . ? 1_655 ? 
43 AC8 8  TYR B 134 ? TYR H 134  . ? 1_655 ? 
44 AC8 8  PHE B 215 A PHE H 204  . ? 1_655 ? 
45 AC8 8  HOH R .   ? HOH I 486  . ? 1_564 ? 
46 AC9 6  ARG B 36  ? ARG H 50   . ? 1_555 ? 
47 AC9 6  LYS B 104 ? LYS H 107  . ? 1_555 ? 
48 AC9 6  PRO B 108 ? PRO H 111  . ? 1_555 ? 
49 AC9 6  GLY B 258 ? GLY H 246  . ? 1_555 ? 
50 AC9 6  GLU B 259 ? GLU H 247  . ? 1_555 ? 
51 AC9 6  HOH Q .   ? HOH H 999  . ? 1_555 ? 
52 BC1 3  PHE C 37  ? PHE I 29   . ? 1_555 ? 
53 BC1 3  THR C 38  ? THR I 30   . ? 1_555 ? 
54 BC1 3  GLY C 83  ? GLY I 75   . ? 1_555 ? 
# 
_database_PDB_matrix.entry_id          3B9F 
_database_PDB_matrix.origx[1][1]       1.000000 
_database_PDB_matrix.origx[1][2]       .000000 
_database_PDB_matrix.origx[1][3]       .000000 
_database_PDB_matrix.origx[2][1]       .000000 
_database_PDB_matrix.origx[2][2]       1.000000 
_database_PDB_matrix.origx[2][3]       .000000 
_database_PDB_matrix.origx[3][1]       .000000 
_database_PDB_matrix.origx[3][2]       .000000 
_database_PDB_matrix.origx[3][3]       1.000000 
_database_PDB_matrix.origx_vector[1]   .00000 
_database_PDB_matrix.origx_vector[2]   .00000 
_database_PDB_matrix.origx_vector[3]   .00000 
# 
_atom_sites.entry_id                    3B9F 
_atom_sites.fract_transf_matrix[1][1]   .022699 
_atom_sites.fract_transf_matrix[1][2]   -.004951 
_atom_sites.fract_transf_matrix[1][3]   -.002582 
_atom_sites.fract_transf_matrix[2][1]   .000000 
_atom_sites.fract_transf_matrix[2][2]   .020963 
_atom_sites.fract_transf_matrix[2][3]   -.003616 
_atom_sites.fract_transf_matrix[3][1]   .000000 
_atom_sites.fract_transf_matrix[3][2]   .000000 
_atom_sites.fract_transf_matrix[3][3]   .010485 
_atom_sites.fract_transf_vector[1]      .00000 
_atom_sites.fract_transf_vector[2]      .00000 
_atom_sites.fract_transf_vector[3]      .00000 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . SER A 1  4   R -34.407 34.815  -63.204 1.00 32.04 ? 1    SER L N   1 
ATOM   2    C CA  . SER A 1  4   R -34.478 34.039  -61.928 1.00 29.63 ? 1    SER L CA  1 
ATOM   3    C C   . SER A 1  4   R -34.909 34.931  -60.771 1.00 30.25 ? 1    SER L C   1 
ATOM   4    O O   . SER A 1  4   R -34.085 35.625  -60.167 1.00 30.37 ? 1    SER L O   1 
ATOM   5    C CB  . SER A 1  4   R -33.117 33.414  -61.613 1.00 31.06 ? 1    SER L CB  1 
ATOM   6    O OG  . SER A 1  4   R -33.170 32.694  -60.394 1.00 24.65 ? 1    SER L OG  1 
ATOM   7    N N   . GLU A 1  5   Q -36.200 34.899  -60.456 1.00 29.35 ? 1    GLU L N   1 
ATOM   8    C CA  . GLU A 1  5   Q -36.747 35.722  -59.382 1.00 29.58 ? 1    GLU L CA  1 
ATOM   9    C C   . GLU A 1  5   Q -36.408 35.187  -57.993 1.00 27.19 ? 1    GLU L C   1 
ATOM   10   O O   . GLU A 1  5   Q -36.603 34.009  -57.697 1.00 25.98 ? 1    GLU L O   1 
ATOM   11   C CB  . GLU A 1  5   Q -38.268 35.843  -59.525 1.00 32.27 ? 1    GLU L CB  1 
ATOM   12   C CG  . GLU A 1  5   Q -39.022 34.550  -59.270 1.00 39.28 ? 1    GLU L CG  1 
ATOM   13   C CD  . GLU A 1  5   Q -40.524 34.704  -59.424 1.00 42.90 ? 1    GLU L CD  1 
ATOM   14   O OE1 . GLU A 1  5   Q -41.092 35.645  -58.825 1.00 45.81 ? 1    GLU L OE1 1 
ATOM   15   O OE2 . GLU A 1  5   Q -41.136 33.879  -60.137 1.00 45.28 ? 1    GLU L OE2 1 
ATOM   16   N N   . TYR A 1  6   P -35.899 36.071  -57.146 1.00 24.40 ? 1    TYR L N   1 
ATOM   17   C CA  . TYR A 1  6   P -35.533 35.711  -55.782 1.00 22.98 ? 1    TYR L CA  1 
ATOM   18   C C   . TYR A 1  6   P -35.689 36.923  -54.879 1.00 22.73 ? 1    TYR L C   1 
ATOM   19   O O   . TYR A 1  6   P -35.212 38.013  -55.199 1.00 24.86 ? 1    TYR L O   1 
ATOM   20   C CB  . TYR A 1  6   P -34.077 35.227  -55.717 1.00 21.07 ? 1    TYR L CB  1 
ATOM   21   C CG  . TYR A 1  6   P -33.639 34.832  -54.320 1.00 18.46 ? 1    TYR L CG  1 
ATOM   22   C CD1 . TYR A 1  6   P -33.972 33.589  -53.791 1.00 17.61 ? 1    TYR L CD1 1 
ATOM   23   C CD2 . TYR A 1  6   P -32.951 35.729  -53.502 1.00 19.01 ? 1    TYR L CD2 1 
ATOM   24   C CE1 . TYR A 1  6   P -33.639 33.249  -52.482 1.00 15.32 ? 1    TYR L CE1 1 
ATOM   25   C CE2 . TYR A 1  6   P -32.613 35.400  -52.190 1.00 15.69 ? 1    TYR L CE2 1 
ATOM   26   C CZ  . TYR A 1  6   P -32.964 34.155  -51.686 1.00 16.26 ? 1    TYR L CZ  1 
ATOM   27   O OH  . TYR A 1  6   P -32.670 33.824  -50.385 1.00 14.19 ? 1    TYR L OH  1 
ATOM   28   N N   A GLN A 1  7   O -36.361 36.722  -53.750 0.20 22.43 ? 1    GLN L N   1 
ATOM   29   N N   B GLN A 1  7   O -36.368 36.734  -53.754 0.80 21.82 ? 1    GLN L N   1 
ATOM   30   C CA  A GLN A 1  7   O -36.584 37.781  -52.773 0.23 21.92 ? 1    GLN L CA  1 
ATOM   31   C CA  B GLN A 1  7   O -36.567 37.813  -52.796 0.77 21.45 ? 1    GLN L CA  1 
ATOM   32   C C   A GLN A 1  7   O -35.689 37.523  -51.567 0.25 21.18 ? 1    GLN L C   1 
ATOM   33   C C   B GLN A 1  7   O -35.688 37.528  -51.586 0.65 20.57 ? 1    GLN L C   1 
ATOM   34   O O   A GLN A 1  7   O -35.816 36.492  -50.908 0.23 20.76 ? 1    GLN L O   1 
ATOM   35   O O   B GLN A 1  7   O -35.820 36.482  -50.950 0.77 19.47 ? 1    GLN L O   1 
ATOM   36   C CB  A GLN A 1  7   O -38.050 37.789  -52.332 0.08 22.62 ? 1    GLN L CB  1 
ATOM   37   C CB  B GLN A 1  7   O -38.035 37.884  -52.369 0.92 22.54 ? 1    GLN L CB  1 
ATOM   38   C CG  A GLN A 1  7   O -38.352 38.721  -51.166 0.57 23.72 ? 1    GLN L CG  1 
ATOM   39   C CG  B GLN A 1  7   O -39.001 38.235  -53.495 0.43 23.25 ? 1    GLN L CG  1 
ATOM   40   C CD  A GLN A 1  7   O -39.806 38.669  -50.735 0.37 24.15 ? 1    GLN L CD  1 
ATOM   41   C CD  B GLN A 1  7   O -38.844 39.664  -53.992 0.63 24.00 ? 1    GLN L CD  1 
ATOM   42   O OE1 A GLN A 1  7   O -40.205 39.333  -49.778 0.17 24.60 ? 1    GLN L OE1 1 
ATOM   43   O OE1 B GLN A 1  7   O -39.497 40.072  -54.952 0.21 23.86 ? 1    GLN L OE1 1 
ATOM   44   N NE2 A GLN A 1  7   O -40.608 37.878  -51.442 0.33 24.65 ? 1    GLN L NE2 1 
ATOM   45   N NE2 B GLN A 1  7   O -37.979 40.431  -53.337 0.32 24.02 ? 1    GLN L NE2 1 
ATOM   46   N N   . THR A 1  8   N -34.783 38.453  -51.279 1.00 20.45 ? 1    THR L N   1 
ATOM   47   C CA  . THR A 1  8   N -33.885 38.283  -50.143 1.00 20.33 ? 1    THR L CA  1 
ATOM   48   C C   . THR A 1  8   N -34.665 38.284  -48.834 1.00 20.94 ? 1    THR L C   1 
ATOM   49   O O   . THR A 1  8   N -35.715 38.926  -48.718 1.00 20.47 ? 1    THR L O   1 
ATOM   50   C CB  . THR A 1  8   N -32.800 39.377  -50.107 1.00 21.58 ? 1    THR L CB  1 
ATOM   51   O OG1 . THR A 1  8   N -33.420 40.668  -50.090 1.00 23.76 ? 1    THR L OG1 1 
ATOM   52   C CG2 . THR A 1  8   N -31.889 39.260  -51.327 1.00 22.09 ? 1    THR L CG2 1 
ATOM   53   N N   . PHE A 1  9   M -34.144 37.551  -47.857 1.00 17.82 ? 1    PHE L N   1 
ATOM   54   C CA  . PHE A 1  9   M -34.779 37.412  -46.553 1.00 18.47 ? 1    PHE L CA  1 
ATOM   55   C C   . PHE A 1  9   M -33.918 37.982  -45.432 1.00 18.99 ? 1    PHE L C   1 
ATOM   56   O O   . PHE A 1  9   M -34.435 38.483  -44.431 1.00 19.46 ? 1    PHE L O   1 
ATOM   57   C CB  . PHE A 1  9   M -35.036 35.923  -46.287 1.00 19.12 ? 1    PHE L CB  1 
ATOM   58   C CG  . PHE A 1  9   M -35.582 35.621  -44.919 1.00 18.57 ? 1    PHE L CG  1 
ATOM   59   C CD1 . PHE A 1  9   M -36.952 35.627  -44.683 1.00 21.76 ? 1    PHE L CD1 1 
ATOM   60   C CD2 . PHE A 1  9   M -34.725 35.299  -43.872 1.00 19.92 ? 1    PHE L CD2 1 
ATOM   61   C CE1 . PHE A 1  9   M -37.461 35.309  -43.416 1.00 21.20 ? 1    PHE L CE1 1 
ATOM   62   C CE2 . PHE A 1  9   M -35.222 34.983  -42.608 1.00 21.53 ? 1    PHE L CE2 1 
ATOM   63   C CZ  . PHE A 1  9   M -36.596 34.988  -42.383 1.00 21.25 ? 1    PHE L CZ  1 
ATOM   64   N N   . PHE A 1  10  L -32.603 37.901  -45.603 1.00 16.23 ? 1    PHE L N   1 
ATOM   65   C CA  . PHE A 1  10  L -31.672 38.370  -44.589 1.00 17.29 ? 1    PHE L CA  1 
ATOM   66   C C   . PHE A 1  10  L -31.159 39.776  -44.850 1.00 17.31 ? 1    PHE L C   1 
ATOM   67   O O   . PHE A 1  10  L -31.388 40.341  -45.911 1.00 19.58 ? 1    PHE L O   1 
ATOM   68   C CB  . PHE A 1  10  L -30.486 37.406  -44.482 1.00 15.46 ? 1    PHE L CB  1 
ATOM   69   C CG  . PHE A 1  10  L -30.883 35.997  -44.112 1.00 15.62 ? 1    PHE L CG  1 
ATOM   70   C CD1 . PHE A 1  10  L -31.114 35.037  -45.097 1.00 18.47 ? 1    PHE L CD1 1 
ATOM   71   C CD2 . PHE A 1  10  L -31.043 35.639  -42.774 1.00 15.58 ? 1    PHE L CD2 1 
ATOM   72   C CE1 . PHE A 1  10  L -31.500 33.739  -44.747 1.00 16.68 ? 1    PHE L CE1 1 
ATOM   73   C CE2 . PHE A 1  10  L -31.428 34.347  -42.417 1.00 17.67 ? 1    PHE L CE2 1 
ATOM   74   C CZ  . PHE A 1  10  L -31.657 33.395  -43.407 1.00 18.27 ? 1    PHE L CZ  1 
ATOM   75   N N   . ASN A 1  11  K -30.463 40.325  -43.863 1.00 17.00 ? 1    ASN L N   1 
ATOM   76   C CA  . ASN A 1  11  K -29.894 41.670  -43.963 1.00 17.81 ? 1    ASN L CA  1 
ATOM   77   C C   . ASN A 1  11  K -28.378 41.546  -44.063 1.00 16.36 ? 1    ASN L C   1 
ATOM   78   O O   . ASN A 1  11  K -27.724 41.069  -43.139 1.00 16.83 ? 1    ASN L O   1 
ATOM   79   C CB  . ASN A 1  11  K -30.254 42.491  -42.729 1.00 19.68 ? 1    ASN L CB  1 
ATOM   80   C CG  . ASN A 1  11  K -29.756 43.925  -42.820 1.00 20.18 ? 1    ASN L CG  1 
ATOM   81   O OD1 . ASN A 1  11  K -28.824 44.223  -43.562 1.00 22.56 ? 1    ASN L OD1 1 
ATOM   82   N ND2 . ASN A 1  11  K -30.370 44.814  -42.052 1.00 24.86 ? 1    ASN L ND2 1 
ATOM   83   N N   . PRO A 1  12  J -27.797 41.979  -45.187 1.00 16.18 ? 1    PRO L N   1 
ATOM   84   C CA  . PRO A 1  12  J -26.349 41.902  -45.389 1.00 17.03 ? 1    PRO L CA  1 
ATOM   85   C C   . PRO A 1  12  J -25.510 42.441  -44.222 1.00 16.79 ? 1    PRO L C   1 
ATOM   86   O O   . PRO A 1  12  J -24.386 42.000  -44.001 1.00 16.47 ? 1    PRO L O   1 
ATOM   87   C CB  . PRO A 1  12  J -26.143 42.695  -46.680 1.00 20.20 ? 1    PRO L CB  1 
ATOM   88   C CG  . PRO A 1  12  J -27.418 42.432  -47.426 1.00 17.80 ? 1    PRO L CG  1 
ATOM   89   C CD  . PRO A 1  12  J -28.461 42.584  -46.357 1.00 19.46 ? 1    PRO L CD  1 
ATOM   90   N N   . ARG A 1  13  I -26.058 43.387  -43.468 1.00 17.89 ? 1    ARG L N   1 
ATOM   91   C CA  . ARG A 1  13  I -25.310 43.944  -42.343 1.00 16.15 ? 1    ARG L CA  1 
ATOM   92   C C   . ARG A 1  13  I -24.870 42.849  -41.379 1.00 13.86 ? 1    ARG L C   1 
ATOM   93   O O   . ARG A 1  13  I -23.788 42.915  -40.794 1.00 13.47 ? 1    ARG L O   1 
ATOM   94   C CB  . ARG A 1  13  I -26.159 44.972  -41.586 1.00 19.00 ? 1    ARG L CB  1 
ATOM   95   C CG  . ARG A 1  13  I -25.518 45.464  -40.292 1.00 16.40 ? 1    ARG L CG  1 
ATOM   96   C CD  . ARG A 1  13  I -26.296 46.624  -39.699 1.00 17.81 ? 1    ARG L CD  1 
ATOM   97   N NE  . ARG A 1  13  I -27.673 46.253  -39.388 1.00 18.59 ? 1    ARG L NE  1 
ATOM   98   C CZ  . ARG A 1  13  I -28.038 45.512  -38.348 1.00 16.77 ? 1    ARG L CZ  1 
ATOM   99   N NH1 . ARG A 1  13  I -27.131 45.055  -37.494 1.00 17.82 ? 1    ARG L NH1 1 
ATOM   100  N NH2 . ARG A 1  13  I -29.322 45.221  -38.168 1.00 21.92 ? 1    ARG L NH2 1 
ATOM   101  N N   . THR A 1  14  H -25.711 41.829  -41.231 1.00 16.46 ? 1    THR L N   1 
ATOM   102  C CA  . THR A 1  14  H -25.418 40.733  -40.321 1.00 14.66 ? 1    THR L CA  1 
ATOM   103  C C   . THR A 1  14  H -25.179 39.417  -41.051 1.00 15.08 ? 1    THR L C   1 
ATOM   104  O O   . THR A 1  14  H -24.467 38.557  -40.552 1.00 14.35 ? 1    THR L O   1 
ATOM   105  C CB  . THR A 1  14  H -26.574 40.530  -39.329 1.00 15.04 ? 1    THR L CB  1 
ATOM   106  O OG1 . THR A 1  14  H -27.796 40.334  -40.050 1.00 16.17 ? 1    THR L OG1 1 
ATOM   107  C CG2 . THR A 1  14  H -26.724 41.763  -38.422 1.00 17.76 ? 1    THR L CG2 1 
ATOM   108  N N   . PHE A 1  15  G -25.762 39.294  -42.239 1.00 13.71 ? 1    PHE L N   1 
ATOM   109  C CA  . PHE A 1  15  G -25.661 38.076  -43.054 1.00 14.09 ? 1    PHE L CA  1 
ATOM   110  C C   . PHE A 1  15  G -24.431 38.037  -43.946 1.00 15.81 ? 1    PHE L C   1 
ATOM   111  O O   . PHE A 1  15  G -23.927 36.965  -44.296 1.00 16.72 ? 1    PHE L O   1 
ATOM   112  C CB  . PHE A 1  15  G -26.900 37.969  -43.940 1.00 14.80 ? 1    PHE L CB  1 
ATOM   113  C CG  . PHE A 1  15  G -27.090 36.616  -44.576 1.00 15.19 ? 1    PHE L CG  1 
ATOM   114  C CD1 . PHE A 1  15  G -27.354 35.501  -43.792 1.00 17.53 ? 1    PHE L CD1 1 
ATOM   115  C CD2 . PHE A 1  15  G -27.050 36.472  -45.956 1.00 15.77 ? 1    PHE L CD2 1 
ATOM   116  C CE1 . PHE A 1  15  G -27.583 34.255  -44.380 1.00 15.87 ? 1    PHE L CE1 1 
ATOM   117  C CE2 . PHE A 1  15  G -27.279 35.232  -46.550 1.00 13.68 ? 1    PHE L CE2 1 
ATOM   118  C CZ  . PHE A 1  15  G -27.545 34.129  -45.760 1.00 15.23 ? 1    PHE L CZ  1 
ATOM   119  N N   . GLY A 1  16  F -23.938 39.208  -44.324 1.00 16.54 ? 1    GLY L N   1 
ATOM   120  C CA  . GLY A 1  16  F -22.811 39.229  -45.230 1.00 15.27 ? 1    GLY L CA  1 
ATOM   121  C C   . GLY A 1  16  F -23.396 39.302  -46.634 1.00 14.88 ? 1    GLY L C   1 
ATOM   122  O O   . GLY A 1  16  F -24.604 39.513  -46.801 1.00 15.02 ? 1    GLY L O   1 
ATOM   123  N N   A SER A 1  17  E -22.556 39.135  -47.649 0.10 14.32 ? 1    SER L N   1 
ATOM   124  N N   B SER A 1  17  E -22.558 39.094  -47.639 0.85 13.30 ? 1    SER L N   1 
ATOM   125  C CA  A SER A 1  17  E -23.019 39.209  -49.032 0.16 13.53 ? 1    SER L CA  1 
ATOM   126  C CA  B SER A 1  17  E -23.010 39.174  -49.023 0.84 12.40 ? 1    SER L CA  1 
ATOM   127  C C   A SER A 1  17  E -23.259 37.839  -49.653 0.10 13.43 ? 1    SER L C   1 
ATOM   128  C C   B SER A 1  17  E -23.296 37.813  -49.635 0.82 12.51 ? 1    SER L C   1 
ATOM   129  O O   A SER A 1  17  E -22.829 36.818  -49.115 0.34 12.37 ? 1    SER L O   1 
ATOM   130  O O   B SER A 1  17  E -22.933 36.779  -49.072 0.42 11.68 ? 1    SER L O   1 
ATOM   131  C CB  A SER A 1  17  E -22.005 39.972  -49.885 0.12 14.46 ? 1    SER L CB  1 
ATOM   132  C CB  B SER A 1  17  E -21.955 39.876  -49.877 0.55 14.97 ? 1    SER L CB  1 
ATOM   133  O OG  A SER A 1  17  E -20.778 39.269  -49.954 0.31 14.33 ? 1    SER L OG  1 
ATOM   134  O OG  B SER A 1  17  E -21.609 41.126  -49.317 0.46 13.88 ? 1    SER L OG  1 
ATOM   135  N N   . GLY A 1  18  D -23.949 37.835  -50.793 1.00 13.00 ? 1    GLY L N   1 
ATOM   136  C CA  . GLY A 1  18  D -24.235 36.599  -51.498 1.00 14.51 ? 1    GLY L CA  1 
ATOM   137  C C   . GLY A 1  18  D -25.658 36.081  -51.579 1.00 14.79 ? 1    GLY L C   1 
ATOM   138  O O   . GLY A 1  18  D -25.960 35.248  -52.438 1.00 14.14 ? 1    GLY L O   1 
ATOM   139  N N   . GLU A 1  19  C -26.551 36.548  -50.721 1.00 14.40 ? 1    GLU L N   1 
ATOM   140  C CA  . GLU A 1  19  C -27.903 36.006  -50.784 1.00 14.74 ? 1    GLU L CA  1 
ATOM   141  C C   . GLU A 1  19  C -28.635 36.273  -52.096 1.00 15.49 ? 1    GLU L C   1 
ATOM   142  O O   . GLU A 1  19  C -29.251 35.375  -52.654 1.00 15.00 ? 1    GLU L O   1 
ATOM   143  C CB  . GLU A 1  19  C -28.771 36.502  -49.623 1.00 15.17 ? 1    GLU L CB  1 
ATOM   144  C CG  . GLU A 1  19  C -30.092 35.728  -49.567 1.00 15.88 ? 1    GLU L CG  1 
ATOM   145  C CD  . GLU A 1  19  C -31.125 36.296  -48.615 1.00 18.16 ? 1    GLU L CD  1 
ATOM   146  O OE1 . GLU A 1  19  C -32.265 35.780  -48.642 1.00 15.51 ? 1    GLU L OE1 1 
ATOM   147  O OE2 . GLU A 1  19  C -30.809 37.240  -47.848 1.00 16.57 ? 1    GLU L OE2 1 
ATOM   148  N N   . ALA A 1  20  B -28.565 37.502  -52.602 1.00 16.09 ? 1    ALA L N   1 
ATOM   149  C CA  . ALA A 1  20  B -29.273 37.838  -53.834 1.00 14.85 ? 1    ALA L CA  1 
ATOM   150  C C   . ALA A 1  20  B -28.977 36.932  -55.019 1.00 14.38 ? 1    ALA L C   1 
ATOM   151  O O   . ALA A 1  20  B -29.865 36.669  -55.830 1.00 15.15 ? 1    ALA L O   1 
ATOM   152  C CB  . ALA A 1  20  B -28.999 39.294  -54.217 1.00 15.70 ? 1    ALA L CB  1 
ATOM   153  N N   . ASP A 1  21  A -27.738 36.457  -55.127 1.00 12.99 ? 1    ASP L N   1 
ATOM   154  C CA  . ASP A 1  21  A -27.359 35.595  -56.242 1.00 15.04 ? 1    ASP L CA  1 
ATOM   155  C C   . ASP A 1  21  A -27.196 34.143  -55.804 1.00 13.44 ? 1    ASP L C   1 
ATOM   156  O O   . ASP A 1  21  A -26.569 33.349  -56.502 1.00 14.98 ? 1    ASP L O   1 
ATOM   157  C CB  . ASP A 1  21  A -26.048 36.095  -56.856 1.00 14.74 ? 1    ASP L CB  1 
ATOM   158  C CG  . ASP A 1  21  A -25.798 35.532  -58.248 1.00 17.73 ? 1    ASP L CG  1 
ATOM   159  O OD1 . ASP A 1  21  A -26.770 35.412  -59.028 1.00 19.01 ? 1    ASP L OD1 1 
ATOM   160  O OD2 . ASP A 1  21  A -24.630 35.226  -58.569 1.00 20.94 ? 1    ASP L OD2 1 
ATOM   161  N N   . CYS A 1  22  ? -27.779 33.791  -54.663 1.00 11.36 ? 1    CYS L N   1 
ATOM   162  C CA  . CYS A 1  22  ? -27.645 32.429  -54.138 1.00 11.72 ? 1    CYS L CA  1 
ATOM   163  C C   . CYS A 1  22  ? -28.184 31.351  -55.065 1.00 12.46 ? 1    CYS L C   1 
ATOM   164  O O   . CYS A 1  22  ? -29.066 31.597  -55.887 1.00 11.13 ? 1    CYS L O   1 
ATOM   165  C CB  . CYS A 1  22  ? -28.357 32.304  -52.778 1.00 12.67 ? 1    CYS L CB  1 
ATOM   166  S SG  . CYS A 1  22  ? -30.171 32.459  -52.875 1.00 11.75 ? 1    CYS L SG  1 
ATOM   167  N N   . GLY A 1  23  ? -27.618 30.155  -54.931 1.00 11.94 ? 2    GLY L N   1 
ATOM   168  C CA  . GLY A 1  23  ? -28.093 29.010  -55.681 1.00 13.42 ? 2    GLY L CA  1 
ATOM   169  C C   . GLY A 1  23  ? -27.920 28.936  -57.179 1.00 13.71 ? 2    GLY L C   1 
ATOM   170  O O   . GLY A 1  23  ? -28.452 28.010  -57.799 1.00 12.21 ? 2    GLY L O   1 
ATOM   171  N N   . LEU A 1  24  ? -27.207 29.893  -57.766 1.00 11.48 ? 3    LEU L N   1 
ATOM   172  C CA  . LEU A 1  24  ? -26.960 29.891  -59.207 1.00 12.60 ? 3    LEU L CA  1 
ATOM   173  C C   . LEU A 1  24  ? -25.462 29.636  -59.346 1.00 13.82 ? 3    LEU L C   1 
ATOM   174  O O   . LEU A 1  24  ? -24.649 30.462  -58.944 1.00 14.29 ? 3    LEU L O   1 
ATOM   175  C CB  . LEU A 1  24  ? -27.338 31.241  -59.823 1.00 11.91 ? 3    LEU L CB  1 
ATOM   176  C CG  . LEU A 1  24  ? -28.829 31.591  -59.751 1.00 13.26 ? 3    LEU L CG  1 
ATOM   177  C CD1 . LEU A 1  24  ? -29.035 33.022  -60.249 1.00 14.61 ? 3    LEU L CD1 1 
ATOM   178  C CD2 . LEU A 1  24  ? -29.646 30.608  -60.592 1.00 14.63 ? 3    LEU L CD2 1 
ATOM   179  N N   . ARG A 1  25  ? -25.112 28.482  -59.906 1.00 12.52 ? 4    ARG L N   1 
ATOM   180  C CA  . ARG A 1  25  ? -23.718 28.076  -60.044 1.00 12.69 ? 4    ARG L CA  1 
ATOM   181  C C   . ARG A 1  25  ? -22.998 28.687  -61.232 1.00 13.53 ? 4    ARG L C   1 
ATOM   182  O O   . ARG A 1  25  ? -23.488 28.641  -62.360 1.00 14.01 ? 4    ARG L O   1 
ATOM   183  C CB  . ARG A 1  25  ? -23.637 26.547  -60.121 1.00 13.49 ? 4    ARG L CB  1 
ATOM   184  C CG  . ARG A 1  25  ? -24.174 25.857  -58.871 1.00 13.24 ? 4    ARG L CG  1 
ATOM   185  C CD  . ARG A 1  25  ? -24.323 24.364  -59.094 1.00 12.86 ? 4    ARG L CD  1 
ATOM   186  N NE  . ARG A 1  25  ? -25.252 24.082  -60.179 1.00 12.30 ? 4    ARG L NE  1 
ATOM   187  C CZ  . ARG A 1  25  ? -25.493 22.858  -60.636 1.00 12.28 ? 4    ARG L CZ  1 
ATOM   188  N NH1 . ARG A 1  25  ? -24.862 21.832  -60.090 1.00 12.74 ? 4    ARG L NH1 1 
ATOM   189  N NH2 . ARG A 1  25  ? -26.368 22.664  -61.617 1.00 14.99 ? 4    ARG L NH2 1 
ATOM   190  N N   . PRO A 1  26  ? -21.817 29.271  -60.984 1.00 15.33 ? 5    PRO L N   1 
ATOM   191  C CA  . PRO A 1  26  ? -20.998 29.905  -62.020 1.00 15.74 ? 5    PRO L CA  1 
ATOM   192  C C   . PRO A 1  26  ? -20.696 28.992  -63.203 1.00 17.42 ? 5    PRO L C   1 
ATOM   193  O O   . PRO A 1  26  ? -20.682 29.442  -64.351 1.00 18.03 ? 5    PRO L O   1 
ATOM   194  C CB  . PRO A 1  26  ? -19.730 30.287  -61.266 1.00 17.22 ? 5    PRO L CB  1 
ATOM   195  C CG  . PRO A 1  26  ? -20.243 30.625  -59.906 1.00 15.79 ? 5    PRO L CG  1 
ATOM   196  C CD  . PRO A 1  26  ? -21.226 29.486  -59.650 1.00 15.15 ? 5    PRO L CD  1 
ATOM   197  N N   . LEU A 1  27  ? -20.462 27.713  -62.927 1.00 15.80 ? 6    LEU L N   1 
ATOM   198  C CA  . LEU A 1  27  ? -20.136 26.766  -63.990 1.00 18.28 ? 6    LEU L CA  1 
ATOM   199  C C   . LEU A 1  27  ? -21.313 25.991  -64.569 1.00 19.71 ? 6    LEU L C   1 
ATOM   200  O O   . LEU A 1  27  ? -21.129 25.129  -65.431 1.00 18.72 ? 6    LEU L O   1 
ATOM   201  C CB  . LEU A 1  27  ? -19.057 25.785  -63.509 1.00 17.98 ? 6    LEU L CB  1 
ATOM   202  C CG  . LEU A 1  27  ? -17.703 26.416  -63.180 1.00 20.61 ? 6    LEU L CG  1 
ATOM   203  C CD1 . LEU A 1  27  ? -16.721 25.341  -62.776 1.00 19.96 ? 6    LEU L CD1 1 
ATOM   204  C CD2 . LEU A 1  27  ? -17.180 27.181  -64.398 1.00 22.51 ? 6    LEU L CD2 1 
ATOM   205  N N   . PHE A 1  28  ? -22.523 26.290  -64.107 1.00 16.42 ? 7    PHE L N   1 
ATOM   206  C CA  . PHE A 1  28  ? -23.689 25.604  -64.625 1.00 16.69 ? 7    PHE L CA  1 
ATOM   207  C C   . PHE A 1  28  ? -24.803 26.573  -64.994 1.00 16.90 ? 7    PHE L C   1 
ATOM   208  O O   . PHE A 1  28  ? -24.865 27.013  -66.137 1.00 17.26 ? 7    PHE L O   1 
ATOM   209  C CB  . PHE A 1  28  ? -24.143 24.531  -63.624 1.00 17.41 ? 7    PHE L CB  1 
ATOM   210  C CG  . PHE A 1  28  ? -23.188 23.369  -63.538 1.00 15.48 ? 7    PHE L CG  1 
ATOM   211  C CD1 . PHE A 1  28  ? -23.219 22.356  -64.495 1.00 16.72 ? 7    PHE L CD1 1 
ATOM   212  C CD2 . PHE A 1  28  ? -22.193 23.339  -62.564 1.00 16.19 ? 7    PHE L CD2 1 
ATOM   213  C CE1 . PHE A 1  28  ? -22.267 21.332  -64.489 1.00 17.28 ? 7    PHE L CE1 1 
ATOM   214  C CE2 . PHE A 1  28  ? -21.235 22.321  -62.545 1.00 15.78 ? 7    PHE L CE2 1 
ATOM   215  C CZ  . PHE A 1  28  ? -21.271 21.314  -63.513 1.00 16.80 ? 7    PHE L CZ  1 
ATOM   216  N N   . GLU A 1  29  ? -25.670 26.926  -64.050 1.00 14.60 ? 8    GLU L N   1 
ATOM   217  C CA  . GLU A 1  29  ? -26.761 27.851  -64.357 1.00 16.37 ? 8    GLU L CA  1 
ATOM   218  C C   . GLU A 1  29  ? -26.307 29.123  -65.073 1.00 18.34 ? 8    GLU L C   1 
ATOM   219  O O   . GLU A 1  29  ? -26.938 29.559  -66.040 1.00 19.66 ? 8    GLU L O   1 
ATOM   220  C CB  . GLU A 1  29  ? -27.513 28.256  -63.082 1.00 17.19 ? 8    GLU L CB  1 
ATOM   221  C CG  . GLU A 1  29  ? -28.412 27.173  -62.491 1.00 15.18 ? 8    GLU L CG  1 
ATOM   222  C CD  . GLU A 1  29  ? -27.632 26.077  -61.796 1.00 13.90 ? 8    GLU L CD  1 
ATOM   223  O OE1 . GLU A 1  29  ? -26.498 26.344  -61.353 1.00 14.86 ? 8    GLU L OE1 1 
ATOM   224  O OE2 . GLU A 1  29  ? -28.162 24.951  -61.683 1.00 13.40 ? 8    GLU L OE2 1 
ATOM   225  N N   . LYS A 1  30  ? -25.218 29.716  -64.598 1.00 18.97 ? 9    LYS L N   1 
ATOM   226  C CA  . LYS A 1  30  ? -24.725 30.953  -65.193 1.00 21.11 ? 9    LYS L CA  1 
ATOM   227  C C   . LYS A 1  30  ? -24.129 30.784  -66.585 1.00 21.84 ? 9    LYS L C   1 
ATOM   228  O O   . LYS A 1  30  ? -23.925 31.768  -67.296 1.00 22.45 ? 9    LYS L O   1 
ATOM   229  C CB  . LYS A 1  30  ? -23.724 31.619  -64.250 1.00 22.48 ? 9    LYS L CB  1 
ATOM   230  C CG  . LYS A 1  30  ? -24.382 32.114  -62.969 1.00 26.08 ? 9    LYS L CG  1 
ATOM   231  C CD  . LYS A 1  30  ? -23.419 32.873  -62.086 1.00 30.65 ? 9    LYS L CD  1 
ATOM   232  C CE  . LYS A 1  30  ? -24.144 33.492  -60.902 1.00 33.64 ? 9    LYS L CE  1 
ATOM   233  N NZ  . LYS A 1  30  ? -25.170 34.486  -61.336 1.00 36.13 ? 9    LYS L NZ  1 
ATOM   234  N N   . LYS A 1  31  ? -23.866 29.540  -66.976 1.00 21.42 ? 10   LYS L N   1 
ATOM   235  C CA  . LYS A 1  31  ? -23.314 29.245  -68.296 1.00 23.10 ? 10   LYS L CA  1 
ATOM   236  C C   . LYS A 1  31  ? -24.335 28.467  -69.120 1.00 24.10 ? 10   LYS L C   1 
ATOM   237  O O   . LYS A 1  31  ? -24.025 27.974  -70.207 1.00 25.29 ? 10   LYS L O   1 
ATOM   238  C CB  . LYS A 1  31  ? -22.035 28.413  -68.174 1.00 24.83 ? 10   LYS L CB  1 
ATOM   239  C CG  . LYS A 1  31  ? -20.870 29.145  -67.547 1.00 27.36 ? 10   LYS L CG  1 
ATOM   240  C CD  . LYS A 1  31  ? -19.632 28.264  -67.482 1.00 26.28 ? 10   LYS L CD  1 
ATOM   241  C CE  . LYS A 1  31  ? -19.124 27.922  -68.863 1.00 28.92 ? 10   LYS L CE  1 
ATOM   242  N NZ  . LYS A 1  31  ? -17.875 27.113  -68.810 1.00 29.82 ? 10   LYS L NZ  1 
ATOM   243  N N   . SER A 1  32  ? -25.549 28.351  -68.593 1.00 22.33 ? 11   SER L N   1 
ATOM   244  C CA  . SER A 1  32  ? -26.614 27.625  -69.269 1.00 22.52 ? 11   SER L CA  1 
ATOM   245  C C   . SER A 1  32  ? -26.195 26.180  -69.533 1.00 22.82 ? 11   SER L C   1 
ATOM   246  O O   . SER A 1  32  ? -26.468 25.622  -70.597 1.00 23.99 ? 11   SER L O   1 
ATOM   247  C CB  . SER A 1  32  ? -26.981 28.321  -70.585 1.00 25.29 ? 11   SER L CB  1 
ATOM   248  O OG  . SER A 1  32  ? -27.433 29.646  -70.345 1.00 27.27 ? 11   SER L OG  1 
ATOM   249  N N   . LEU A 1  33  ? -25.513 25.588  -68.557 1.00 21.05 ? 12   LEU L N   1 
ATOM   250  C CA  . LEU A 1  33  ? -25.065 24.203  -68.643 1.00 20.77 ? 12   LEU L CA  1 
ATOM   251  C C   . LEU A 1  33  ? -25.722 23.431  -67.506 1.00 21.03 ? 12   LEU L C   1 
ATOM   252  O O   . LEU A 1  33  ? -25.873 23.956  -66.410 1.00 19.01 ? 12   LEU L O   1 
ATOM   253  C CB  . LEU A 1  33  ? -23.543 24.110  -68.493 1.00 21.18 ? 12   LEU L CB  1 
ATOM   254  C CG  . LEU A 1  33  ? -22.665 24.685  -69.610 1.00 21.14 ? 12   LEU L CG  1 
ATOM   255  C CD1 . LEU A 1  33  ? -21.196 24.459  -69.275 1.00 22.87 ? 12   LEU L CD1 1 
ATOM   256  C CD2 . LEU A 1  33  ? -23.012 24.010  -70.928 1.00 23.34 ? 12   LEU L CD2 1 
ATOM   257  N N   . GLU A 1  34  ? -26.111 22.190  -67.775 1.00 20.83 ? 13   GLU L N   1 
ATOM   258  C CA  . GLU A 1  34  ? -26.740 21.332  -66.771 1.00 21.21 ? 13   GLU L CA  1 
ATOM   259  C C   . GLU A 1  34  ? -25.712 20.339  -66.269 1.00 20.62 ? 13   GLU L C   1 
ATOM   260  O O   . GLU A 1  34  ? -24.819 19.944  -67.025 1.00 19.53 ? 13   GLU L O   1 
ATOM   261  C CB  . GLU A 1  34  ? -27.883 20.527  -67.391 1.00 23.42 ? 13   GLU L CB  1 
ATOM   262  C CG  . GLU A 1  34  ? -29.244 21.176  -67.374 1.00 28.91 ? 13   GLU L CG  1 
ATOM   263  C CD  . GLU A 1  34  ? -30.271 20.332  -68.102 1.00 30.01 ? 13   GLU L CD  1 
ATOM   264  O OE1 . GLU A 1  34  ? -30.294 19.099  -67.882 1.00 31.37 ? 13   GLU L OE1 1 
ATOM   265  O OE2 . GLU A 1  34  ? -31.058 20.900  -68.888 1.00 31.68 ? 13   GLU L OE2 1 
ATOM   266  N N   . ASP A 1  35  ? -25.807 19.933  -65.004 1.00 17.72 ? 14   ASP L N   1 
ATOM   267  C CA  . ASP A 1  35  ? -24.871 18.929  -64.537 1.00 15.90 ? 14   ASP L CA  1 
ATOM   268  C C   . ASP A 1  35  ? -25.460 17.589  -64.974 1.00 15.69 ? 14   ASP L C   1 
ATOM   269  O O   . ASP A 1  35  ? -26.583 17.540  -65.481 1.00 16.34 ? 14   ASP L O   1 
ATOM   270  C CB  . ASP A 1  35  ? -24.620 19.007  -63.015 1.00 15.19 ? 14   ASP L CB  1 
ATOM   271  C CG  . ASP A 1  35  ? -25.858 18.744  -62.177 1.00 17.32 ? 14   ASP L CG  1 
ATOM   272  O OD1 . ASP A 1  35  ? -26.500 17.693  -62.351 1.00 16.19 ? 14   ASP L OD1 1 
ATOM   273  O OD2 . ASP A 1  35  ? -26.166 19.587  -61.309 1.00 15.09 ? 14   ASP L OD2 1 
ATOM   274  N N   . LYS A 1  36  A -24.703 16.516  -64.801 1.00 16.87 ? 14   LYS L N   1 
ATOM   275  C CA  . LYS A 1  36  A -25.127 15.192  -65.251 1.00 20.20 ? 14   LYS L CA  1 
ATOM   276  C C   . LYS A 1  36  A -26.404 14.572  -64.705 1.00 19.39 ? 14   LYS L C   1 
ATOM   277  O O   . LYS A 1  36  A -27.042 13.775  -65.394 1.00 19.20 ? 14   LYS L O   1 
ATOM   278  C CB  . LYS A 1  36  A -23.982 14.200  -65.050 1.00 23.13 ? 14   LYS L CB  1 
ATOM   279  C CG  . LYS A 1  36  A -22.802 14.438  -65.975 1.00 29.76 ? 14   LYS L CG  1 
ATOM   280  C CD  . LYS A 1  36  A -21.636 13.522  -65.632 1.00 33.06 ? 14   LYS L CD  1 
ATOM   281  C CE  . LYS A 1  36  A -20.462 13.761  -66.576 1.00 35.75 ? 14   LYS L CE  1 
ATOM   282  N NZ  . LYS A 1  36  A -19.291 12.914  -66.224 1.00 38.60 ? 14   LYS L NZ  1 
ATOM   283  N N   . THR A 1  37  B -26.791 14.917  -63.485 1.00 19.40 ? 14   THR L N   1 
ATOM   284  C CA  . THR A 1  37  B -27.982 14.299  -62.918 1.00 17.35 ? 14   THR L CA  1 
ATOM   285  C C   . THR A 1  37  B -29.115 15.212  -62.461 1.00 16.24 ? 14   THR L C   1 
ATOM   286  O O   . THR A 1  37  B -30.100 14.726  -61.905 1.00 16.02 ? 14   THR L O   1 
ATOM   287  C CB  . THR A 1  37  B -27.603 13.386  -61.731 1.00 17.83 ? 14   THR L CB  1 
ATOM   288  O OG1 . THR A 1  37  B -27.071 14.177  -60.665 1.00 17.83 ? 14   THR L OG1 1 
ATOM   289  C CG2 . THR A 1  37  B -26.550 12.356  -62.163 1.00 21.60 ? 14   THR L CG2 1 
ATOM   290  N N   . GLU A 1  38  C -29.014 16.518  -62.690 1.00 15.40 ? 14   GLU L N   1 
ATOM   291  C CA  . GLU A 1  38  C -30.102 17.379  -62.244 1.00 15.21 ? 14   GLU L CA  1 
ATOM   292  C C   . GLU A 1  38  C -31.419 17.092  -62.955 1.00 16.56 ? 14   GLU L C   1 
ATOM   293  O O   . GLU A 1  38  C -32.486 17.362  -62.408 1.00 17.56 ? 14   GLU L O   1 
ATOM   294  C CB  . GLU A 1  38  C -29.739 18.865  -62.364 1.00 13.74 ? 14   GLU L CB  1 
ATOM   295  C CG  . GLU A 1  38  C -29.372 19.371  -63.744 1.00 13.23 ? 14   GLU L CG  1 
ATOM   296  C CD  . GLU A 1  38  C -29.143 20.877  -63.740 1.00 15.88 ? 14   GLU L CD  1 
ATOM   297  O OE1 . GLU A 1  38  C -30.135 21.634  -63.698 1.00 16.90 ? 14   GLU L OE1 1 
ATOM   298  O OE2 . GLU A 1  38  C -27.973 21.305  -63.763 1.00 15.91 ? 14   GLU L OE2 1 
ATOM   299  N N   . ARG A 1  39  D -31.355 16.521  -64.158 1.00 16.70 ? 14   ARG L N   1 
ATOM   300  C CA  . ARG A 1  39  D -32.579 16.190  -64.884 1.00 17.83 ? 14   ARG L CA  1 
ATOM   301  C C   . ARG A 1  39  D -33.397 15.184  -64.069 1.00 16.83 ? 14   ARG L C   1 
ATOM   302  O O   . ARG A 1  39  D -34.631 15.224  -64.070 1.00 16.16 ? 14   ARG L O   1 
ATOM   303  C CB  . ARG A 1  39  D -32.247 15.592  -66.255 1.00 17.15 ? 14   ARG L CB  1 
ATOM   304  C CG  . ARG A 1  39  D -33.462 15.085  -67.024 1.00 20.48 ? 14   ARG L CG  1 
ATOM   305  C CD  . ARG A 1  39  D -34.366 16.218  -67.475 1.00 24.23 ? 14   ARG L CD  1 
ATOM   306  N NE  . ARG A 1  39  D -35.553 15.720  -68.166 1.00 27.00 ? 14   ARG L NE  1 
ATOM   307  C CZ  . ARG A 1  39  D -36.330 16.467  -68.944 1.00 27.40 ? 14   ARG L CZ  1 
ATOM   308  N NH1 . ARG A 1  39  D -36.045 17.747  -69.133 1.00 24.13 ? 14   ARG L NH1 1 
ATOM   309  N NH2 . ARG A 1  39  D -37.394 15.932  -69.533 1.00 29.09 ? 14   ARG L NH2 1 
ATOM   310  N N   . GLU A 1  40  E -32.702 14.296  -63.363 1.00 16.69 ? 14   GLU L N   1 
ATOM   311  C CA  . GLU A 1  40  E -33.357 13.283  -62.538 1.00 17.08 ? 14   GLU L CA  1 
ATOM   312  C C   . GLU A 1  40  E -34.189 13.950  -61.444 1.00 15.97 ? 14   GLU L C   1 
ATOM   313  O O   . GLU A 1  40  E -35.279 13.486  -61.102 1.00 15.47 ? 14   GLU L O   1 
ATOM   314  C CB  . GLU A 1  40  E -32.310 12.354  -61.909 1.00 19.01 ? 14   GLU L CB  1 
ATOM   315  C CG  . GLU A 1  40  E -32.871 11.383  -60.867 1.00 19.95 ? 14   GLU L CG  1 
ATOM   316  C CD  . GLU A 1  40  E -31.802 10.504  -60.233 1.00 21.68 ? 14   GLU L CD  1 
ATOM   317  O OE1 . GLU A 1  40  E -30.599 10.805  -60.396 1.00 19.83 ? 14   GLU L OE1 1 
ATOM   318  O OE2 . GLU A 1  40  E -32.166 9.516   -59.558 1.00 21.04 ? 14   GLU L OE2 1 
ATOM   319  N N   . LEU A 1  41  F -33.668 15.045  -60.902 1.00 15.29 ? 14   LEU L N   1 
ATOM   320  C CA  . LEU A 1  41  F -34.374 15.774  -59.857 1.00 15.73 ? 14   LEU L CA  1 
ATOM   321  C C   . LEU A 1  41  F -35.622 16.427  -60.440 1.00 14.56 ? 14   LEU L C   1 
ATOM   322  O O   . LEU A 1  41  F -36.705 16.312  -59.879 1.00 15.09 ? 14   LEU L O   1 
ATOM   323  C CB  . LEU A 1  41  F -33.468 16.848  -59.250 1.00 14.86 ? 14   LEU L CB  1 
ATOM   324  C CG  . LEU A 1  41  F -32.141 16.344  -58.680 1.00 15.84 ? 14   LEU L CG  1 
ATOM   325  C CD1 . LEU A 1  41  F -31.368 17.508  -58.068 1.00 15.35 ? 14   LEU L CD1 1 
ATOM   326  C CD2 . LEU A 1  41  F -32.408 15.281  -57.625 1.00 16.34 ? 14   LEU L CD2 1 
ATOM   327  N N   . LEU A 1  42  G -35.464 17.115  -61.566 1.00 14.26 ? 14   LEU L N   1 
ATOM   328  C CA  . LEU A 1  42  G -36.597 17.778  -62.201 1.00 15.98 ? 14   LEU L CA  1 
ATOM   329  C C   . LEU A 1  42  G -37.671 16.771  -62.597 1.00 15.55 ? 14   LEU L C   1 
ATOM   330  O O   . LEU A 1  42  G -38.869 17.047  -62.483 1.00 16.87 ? 14   LEU L O   1 
ATOM   331  C CB  . LEU A 1  42  G -36.125 18.571  -63.427 1.00 17.46 ? 14   LEU L CB  1 
ATOM   332  C CG  . LEU A 1  42  G -35.415 19.915  -63.181 1.00 23.01 ? 14   LEU L CG  1 
ATOM   333  C CD1 . LEU A 1  42  G -36.422 20.920  -62.652 1.00 25.19 ? 14   LEU L CD1 1 
ATOM   334  C CD2 . LEU A 1  42  G -34.246 19.756  -62.207 1.00 26.38 ? 14   LEU L CD2 1 
ATOM   335  N N   . GLU A 1  43  H -37.250 15.595  -63.051 1.00 16.35 ? 14   GLU L N   1 
ATOM   336  C CA  . GLU A 1  43  H -38.221 14.573  -63.438 1.00 16.72 ? 14   GLU L CA  1 
ATOM   337  C C   . GLU A 1  43  H -38.995 14.021  -62.242 1.00 16.82 ? 14   GLU L C   1 
ATOM   338  O O   . GLU A 1  43  H -40.137 13.567  -62.385 1.00 15.82 ? 14   GLU L O   1 
ATOM   339  C CB  . GLU A 1  43  H -37.522 13.433  -64.174 1.00 17.86 ? 14   GLU L CB  1 
ATOM   340  C CG  . GLU A 1  43  H -36.955 13.859  -65.511 1.00 20.69 ? 14   GLU L CG  1 
ATOM   341  C CD  . GLU A 1  43  H -36.272 12.728  -66.240 1.00 24.03 ? 14   GLU L CD  1 
ATOM   342  O OE1 . GLU A 1  43  H -35.903 11.736  -65.580 1.00 26.84 ? 14   GLU L OE1 1 
ATOM   343  O OE2 . GLU A 1  43  H -36.089 12.843  -67.469 1.00 23.42 ? 14   GLU L OE2 1 
ATOM   344  N N   . SER A 1  44  I -38.390 14.073  -61.057 1.00 15.89 ? 14   SER L N   1 
ATOM   345  C CA  . SER A 1  44  I -39.056 13.566  -59.864 1.00 16.42 ? 14   SER L CA  1 
ATOM   346  C C   . SER A 1  44  I -40.258 14.437  -59.484 1.00 17.51 ? 14   SER L C   1 
ATOM   347  O O   . SER A 1  44  I -41.112 14.016  -58.700 1.00 18.52 ? 14   SER L O   1 
ATOM   348  C CB  . SER A 1  44  I -38.077 13.495  -58.684 1.00 14.51 ? 14   SER L CB  1 
ATOM   349  O OG  . SER A 1  44  I -37.840 14.786  -58.137 1.00 14.85 ? 14   SER L OG  1 
ATOM   350  N N   . TYR A 1  45  J -40.325 15.648  -60.033 1.00 17.02 ? 14   TYR L N   1 
ATOM   351  C CA  . TYR A 1  45  J -41.443 16.544  -59.731 1.00 19.82 ? 14   TYR L CA  1 
ATOM   352  C C   . TYR A 1  45  J -42.684 16.221  -60.554 1.00 22.48 ? 14   TYR L C   1 
ATOM   353  O O   . TYR A 1  45  J -43.767 16.731  -60.267 1.00 24.42 ? 14   TYR L O   1 
ATOM   354  C CB  . TYR A 1  45  J -41.067 18.004  -59.988 1.00 18.75 ? 14   TYR L CB  1 
ATOM   355  C CG  . TYR A 1  45  J -39.871 18.503  -59.215 1.00 17.64 ? 14   TYR L CG  1 
ATOM   356  C CD1 . TYR A 1  45  J -39.617 18.063  -57.914 1.00 18.52 ? 14   TYR L CD1 1 
ATOM   357  C CD2 . TYR A 1  45  J -39.031 19.471  -59.759 1.00 17.19 ? 14   TYR L CD2 1 
ATOM   358  C CE1 . TYR A 1  45  J -38.554 18.585  -57.172 1.00 17.70 ? 14   TYR L CE1 1 
ATOM   359  C CE2 . TYR A 1  45  J -37.968 19.997  -59.030 1.00 18.49 ? 14   TYR L CE2 1 
ATOM   360  C CZ  . TYR A 1  45  J -37.737 19.553  -57.740 1.00 17.37 ? 14   TYR L CZ  1 
ATOM   361  O OH  . TYR A 1  45  J -36.697 20.080  -57.011 1.00 17.47 ? 14   TYR L OH  1 
ATOM   362  N N   . ILE A 1  46  K -42.528 15.390  -61.580 1.00 23.64 ? 14   ILE L N   1 
ATOM   363  C CA  . ILE A 1  46  K -43.656 15.022  -62.436 1.00 28.70 ? 14   ILE L CA  1 
ATOM   364  C C   . ILE A 1  46  K -44.557 14.012  -61.732 1.00 31.59 ? 14   ILE L C   1 
ATOM   365  O O   . ILE A 1  46  K -44.090 12.974  -61.272 1.00 32.34 ? 14   ILE L O   1 
ATOM   366  C CB  . ILE A 1  46  K -43.177 14.384  -63.755 1.00 27.80 ? 14   ILE L CB  1 
ATOM   367  C CG1 . ILE A 1  46  K -42.200 15.314  -64.472 1.00 27.48 ? 14   ILE L CG1 1 
ATOM   368  C CG2 . ILE A 1  46  K -44.371 14.089  -64.651 1.00 28.40 ? 14   ILE L CG2 1 
ATOM   369  C CD1 . ILE A 1  46  K -41.520 14.664  -65.656 1.00 27.86 ? 14   ILE L CD1 1 
ATOM   370  N N   . ASP A 1  47  L -45.849 14.305  -61.657 1.00 36.92 ? 14   ASP L N   1 
ATOM   371  C CA  . ASP A 1  47  L -46.771 13.386  -61.003 1.00 41.35 ? 14   ASP L CA  1 
ATOM   372  C C   . ASP A 1  47  L -48.192 13.551  -61.531 1.00 43.22 ? 14   ASP L C   1 
ATOM   373  O O   . ASP A 1  47  L -48.973 12.588  -61.367 1.00 44.43 ? 14   ASP L O   1 
ATOM   374  C CB  . ASP A 1  47  L -46.749 13.611  -59.490 1.00 44.54 ? 14   ASP L CB  1 
ATOM   375  C CG  . ASP A 1  47  L -47.168 12.378  -58.710 1.00 47.35 ? 14   ASP L CG  1 
ATOM   376  O OD1 . ASP A 1  47  L -48.238 11.810  -59.016 1.00 50.24 ? 14   ASP L OD1 1 
ATOM   377  O OD2 . ASP A 1  47  L -46.426 11.980  -57.786 1.00 49.32 ? 14   ASP L OD2 1 
ATOM   378  N N   . ILE B 2  1   ? -20.577 9.065   -48.594 1.00 12.33 ? 16   ILE H N   1 
ATOM   379  C CA  . ILE B 2  1   ? -21.772 8.855   -49.460 1.00 13.91 ? 16   ILE H CA  1 
ATOM   380  C C   . ILE B 2  1   ? -21.716 7.446   -50.036 1.00 16.79 ? 16   ILE H C   1 
ATOM   381  O O   . ILE B 2  1   ? -20.706 7.054   -50.628 1.00 16.46 ? 16   ILE H O   1 
ATOM   382  C CB  . ILE B 2  1   ? -21.799 9.852   -50.641 1.00 14.11 ? 16   ILE H CB  1 
ATOM   383  C CG1 . ILE B 2  1   ? -21.830 11.289  -50.112 1.00 16.63 ? 16   ILE H CG1 1 
ATOM   384  C CG2 . ILE B 2  1   ? -23.002 9.577   -51.532 1.00 14.95 ? 16   ILE H CG2 1 
ATOM   385  C CD1 . ILE B 2  1   ? -23.092 11.638  -49.356 1.00 15.82 ? 16   ILE H CD1 1 
ATOM   386  N N   . VAL B 2  2   ? -22.804 6.701   -49.868 1.00 15.24 ? 17   VAL H N   1 
ATOM   387  C CA  . VAL B 2  2   ? -22.896 5.331   -50.371 1.00 15.95 ? 17   VAL H CA  1 
ATOM   388  C C   . VAL B 2  2   ? -23.659 5.292   -51.694 1.00 17.85 ? 17   VAL H C   1 
ATOM   389  O O   . VAL B 2  2   ? -24.738 5.885   -51.822 1.00 16.49 ? 17   VAL H O   1 
ATOM   390  C CB  . VAL B 2  2   ? -23.637 4.417   -49.363 1.00 17.40 ? 17   VAL H CB  1 
ATOM   391  C CG1 . VAL B 2  2   ? -23.672 2.979   -49.893 1.00 17.37 ? 17   VAL H CG1 1 
ATOM   392  C CG2 . VAL B 2  2   ? -22.967 4.477   -48.008 1.00 19.28 ? 17   VAL H CG2 1 
ATOM   393  N N   . GLU B 2  3   ? -23.095 4.595   -52.679 1.00 17.63 ? 18   GLU H N   1 
ATOM   394  C CA  . GLU B 2  3   ? -23.729 4.444   -53.989 1.00 20.57 ? 18   GLU H CA  1 
ATOM   395  C C   . GLU B 2  3   ? -23.925 5.751   -54.748 1.00 20.43 ? 18   GLU H C   1 
ATOM   396  O O   . GLU B 2  3   ? -24.888 5.908   -55.500 1.00 20.63 ? 18   GLU H O   1 
ATOM   397  C CB  . GLU B 2  3   ? -25.081 3.732   -53.836 1.00 24.11 ? 18   GLU H CB  1 
ATOM   398  C CG  . GLU B 2  3   ? -24.995 2.292   -53.341 1.00 29.75 ? 18   GLU H CG  1 
ATOM   399  C CD  . GLU B 2  3   ? -24.391 1.352   -54.369 1.00 32.71 ? 18   GLU H CD  1 
ATOM   400  O OE1 . GLU B 2  3   ? -24.847 1.370   -55.531 1.00 33.91 ? 18   GLU H OE1 1 
ATOM   401  O OE2 . GLU B 2  3   ? -23.467 0.589   -54.013 1.00 37.45 ? 18   GLU H OE2 1 
ATOM   402  N N   . GLY B 2  4   ? -23.006 6.688   -54.546 1.00 19.04 ? 19   GLY H N   1 
ATOM   403  C CA  . GLY B 2  4   ? -23.082 7.955   -55.242 1.00 19.70 ? 19   GLY H CA  1 
ATOM   404  C C   . GLY B 2  4   ? -22.100 7.927   -56.399 1.00 21.21 ? 19   GLY H C   1 
ATOM   405  O O   . GLY B 2  4   ? -21.649 6.855   -56.820 1.00 20.67 ? 19   GLY H O   1 
ATOM   406  N N   . SER B 2  5   ? -21.768 9.101   -56.920 1.00 20.49 ? 20   SER H N   1 
ATOM   407  C CA  . SER B 2  5   ? -20.823 9.200   -58.026 1.00 21.67 ? 20   SER H CA  1 
ATOM   408  C C   . SER B 2  5   ? -19.952 10.428  -57.814 1.00 21.85 ? 20   SER H C   1 
ATOM   409  O O   . SER B 2  5   ? -20.225 11.244  -56.930 1.00 18.47 ? 20   SER H O   1 
ATOM   410  C CB  . SER B 2  5   ? -21.568 9.323   -59.358 1.00 24.47 ? 20   SER H CB  1 
ATOM   411  O OG  . SER B 2  5   ? -22.348 10.509  -59.399 1.00 28.39 ? 20   SER H OG  1 
ATOM   412  N N   . ASP B 2  6   ? -18.897 10.553  -58.614 1.00 20.09 ? 21   ASP H N   1 
ATOM   413  C CA  . ASP B 2  6   ? -18.011 11.703  -58.503 1.00 21.04 ? 21   ASP H CA  1 
ATOM   414  C C   . ASP B 2  6   ? -18.760 12.962  -58.902 1.00 19.64 ? 21   ASP H C   1 
ATOM   415  O O   . ASP B 2  6   ? -19.464 12.984  -59.915 1.00 19.18 ? 21   ASP H O   1 
ATOM   416  C CB  . ASP B 2  6   ? -16.802 11.570  -59.434 1.00 21.21 ? 21   ASP H CB  1 
ATOM   417  C CG  . ASP B 2  6   ? -15.858 10.460  -59.028 1.00 23.43 ? 21   ASP H CG  1 
ATOM   418  O OD1 . ASP B 2  6   ? -16.047 9.848   -57.956 1.00 20.32 ? 21   ASP H OD1 1 
ATOM   419  O OD2 . ASP B 2  6   ? -14.905 10.210  -59.796 1.00 24.42 ? 21   ASP H OD2 1 
ATOM   420  N N   . ALA B 2  7   ? -18.602 14.012  -58.107 1.00 19.34 ? 22   ALA H N   1 
ATOM   421  C CA  . ALA B 2  7   ? -19.237 15.282  -58.407 1.00 18.96 ? 22   ALA H CA  1 
ATOM   422  C C   . ALA B 2  7   ? -18.468 15.899  -59.565 1.00 19.64 ? 22   ALA H C   1 
ATOM   423  O O   . ALA B 2  7   ? -17.307 15.569  -59.792 1.00 19.75 ? 22   ALA H O   1 
ATOM   424  C CB  . ALA B 2  7   ? -19.166 16.204  -57.196 1.00 18.45 ? 22   ALA H CB  1 
ATOM   425  N N   . GLU B 2  8   ? -19.120 16.779  -60.310 1.00 19.35 ? 23   GLU H N   1 
ATOM   426  C CA  . GLU B 2  8   ? -18.454 17.462  -61.400 1.00 18.80 ? 23   GLU H CA  1 
ATOM   427  C C   . GLU B 2  8   ? -17.844 18.709  -60.779 1.00 18.66 ? 23   GLU H C   1 
ATOM   428  O O   . GLU B 2  8   ? -18.270 19.141  -59.712 1.00 18.39 ? 23   GLU H O   1 
ATOM   429  C CB  . GLU B 2  8   ? -19.459 17.852  -62.475 1.00 18.08 ? 23   GLU H CB  1 
ATOM   430  C CG  . GLU B 2  8   ? -20.041 16.664  -63.206 1.00 21.25 ? 23   GLU H CG  1 
ATOM   431  C CD  . GLU B 2  8   ? -21.298 17.019  -63.960 1.00 22.83 ? 23   GLU H CD  1 
ATOM   432  O OE1 . GLU B 2  8   ? -21.216 17.788  -64.939 1.00 23.07 ? 23   GLU H OE1 1 
ATOM   433  O OE2 . GLU B 2  8   ? -22.373 16.530  -63.559 1.00 25.22 ? 23   GLU H OE2 1 
ATOM   434  N N   . ILE B 2  9   ? -16.837 19.275  -61.431 1.00 19.40 ? 24   ILE H N   1 
ATOM   435  C CA  . ILE B 2  9   ? -16.198 20.474  -60.909 1.00 19.60 ? 24   ILE H CA  1 
ATOM   436  C C   . ILE B 2  9   ? -17.217 21.610  -60.786 1.00 18.79 ? 24   ILE H C   1 
ATOM   437  O O   . ILE B 2  9   ? -17.980 21.878  -61.717 1.00 17.89 ? 24   ILE H O   1 
ATOM   438  C CB  . ILE B 2  9   ? -15.029 20.913  -61.828 1.00 20.83 ? 24   ILE H CB  1 
ATOM   439  C CG1 . ILE B 2  9   ? -13.970 19.807  -61.875 1.00 22.82 ? 24   ILE H CG1 1 
ATOM   440  C CG2 . ILE B 2  9   ? -14.420 22.212  -61.337 1.00 22.34 ? 24   ILE H CG2 1 
ATOM   441  C CD1 . ILE B 2  9   ? -13.365 19.468  -60.532 1.00 26.55 ? 24   ILE H CD1 1 
ATOM   442  N N   . GLY B 2  10  ? -17.229 22.255  -59.619 1.00 19.19 ? 25   GLY H N   1 
ATOM   443  C CA  . GLY B 2  10  ? -18.135 23.365  -59.372 1.00 17.99 ? 25   GLY H CA  1 
ATOM   444  C C   . GLY B 2  10  ? -19.602 22.992  -59.288 1.00 16.81 ? 25   GLY H C   1 
ATOM   445  O O   . GLY B 2  10  ? -20.469 23.866  -59.330 1.00 16.12 ? 25   GLY H O   1 
ATOM   446  N N   . MET B 2  11  ? -19.884 21.700  -59.161 1.00 16.16 ? 26   MET H N   1 
ATOM   447  C CA  . MET B 2  11  ? -21.260 21.221  -59.090 1.00 14.80 ? 26   MET H CA  1 
ATOM   448  C C   . MET B 2  11  ? -21.956 21.572  -57.771 1.00 14.69 ? 26   MET H C   1 
ATOM   449  O O   . MET B 2  11  ? -23.182 21.711  -57.725 1.00 14.33 ? 26   MET H O   1 
ATOM   450  C CB  . MET B 2  11  ? -21.271 19.704  -59.305 1.00 16.50 ? 26   MET H CB  1 
ATOM   451  C CG  . MET B 2  11  ? -22.612 19.040  -59.187 1.00 19.62 ? 26   MET H CG  1 
ATOM   452  S SD  . MET B 2  11  ? -22.411 17.248  -59.337 1.00 21.23 ? 26   MET H SD  1 
ATOM   453  C CE  . MET B 2  11  ? -23.799 16.842  -60.382 1.00 25.07 ? 26   MET H CE  1 
ATOM   454  N N   . SER B 2  12  ? -21.170 21.726  -56.710 1.00 13.99 ? 27   SER H N   1 
ATOM   455  C CA  . SER B 2  12  ? -21.695 22.042  -55.379 1.00 14.12 ? 27   SER H CA  1 
ATOM   456  C C   . SER B 2  12  ? -20.757 23.087  -54.784 1.00 12.83 ? 27   SER H C   1 
ATOM   457  O O   . SER B 2  12  ? -20.043 22.825  -53.813 1.00 13.93 ? 27   SER H O   1 
ATOM   458  C CB  . SER B 2  12  ? -21.691 20.764  -54.528 1.00 16.04 ? 27   SER H CB  1 
ATOM   459  O OG  . SER B 2  12  ? -22.345 20.944  -53.286 1.00 15.32 ? 27   SER H OG  1 
ATOM   460  N N   . PRO B 2  13  ? -20.766 24.303  -55.350 1.00 13.68 ? 28   PRO H N   1 
ATOM   461  C CA  . PRO B 2  13  ? -19.891 25.385  -54.878 1.00 12.93 ? 28   PRO H CA  1 
ATOM   462  C C   . PRO B 2  13  ? -20.096 25.885  -53.455 1.00 13.02 ? 28   PRO H C   1 
ATOM   463  O O   . PRO B 2  13  ? -19.286 26.672  -52.943 1.00 12.01 ? 28   PRO H O   1 
ATOM   464  C CB  . PRO B 2  13  ? -20.089 26.465  -55.940 1.00 13.75 ? 28   PRO H CB  1 
ATOM   465  C CG  . PRO B 2  13  ? -21.514 26.292  -56.329 1.00 12.73 ? 28   PRO H CG  1 
ATOM   466  C CD  . PRO B 2  13  ? -21.645 24.773  -56.437 1.00 12.95 ? 28   PRO H CD  1 
ATOM   467  N N   . TRP B 2  14  ? -21.166 25.419  -52.817 1.00 12.64 ? 29   TRP H N   1 
ATOM   468  C CA  . TRP B 2  14  ? -21.474 25.776  -51.434 1.00 10.40 ? 29   TRP H CA  1 
ATOM   469  C C   . TRP B 2  14  ? -20.944 24.705  -50.478 1.00 9.80  ? 29   TRP H C   1 
ATOM   470  O O   . TRP B 2  14  ? -21.097 24.809  -49.261 1.00 10.15 ? 29   TRP H O   1 
ATOM   471  C CB  . TRP B 2  14  ? -22.993 25.929  -51.262 1.00 10.80 ? 29   TRP H CB  1 
ATOM   472  C CG  . TRP B 2  14  ? -23.791 24.999  -52.130 1.00 12.13 ? 29   TRP H CG  1 
ATOM   473  C CD1 . TRP B 2  14  ? -24.061 23.672  -51.898 1.00 10.96 ? 29   TRP H CD1 1 
ATOM   474  C CD2 . TRP B 2  14  ? -24.383 25.314  -53.396 1.00 12.02 ? 29   TRP H CD2 1 
ATOM   475  N NE1 . TRP B 2  14  ? -24.783 23.152  -52.947 1.00 12.97 ? 29   TRP H NE1 1 
ATOM   476  C CE2 . TRP B 2  14  ? -24.996 24.134  -53.879 1.00 12.61 ? 29   TRP H CE2 1 
ATOM   477  C CE3 . TRP B 2  14  ? -24.456 26.479  -54.169 1.00 11.55 ? 29   TRP H CE3 1 
ATOM   478  C CZ2 . TRP B 2  14  ? -25.675 24.088  -55.106 1.00 12.21 ? 29   TRP H CZ2 1 
ATOM   479  C CZ3 . TRP B 2  14  ? -25.135 26.434  -55.397 1.00 11.69 ? 29   TRP H CZ3 1 
ATOM   480  C CH2 . TRP B 2  14  ? -25.735 25.241  -55.848 1.00 12.00 ? 29   TRP H CH2 1 
ATOM   481  N N   . GLN B 2  15  ? -20.319 23.669  -51.034 1.00 11.26 ? 30   GLN H N   1 
ATOM   482  C CA  . GLN B 2  15  ? -19.785 22.587  -50.216 1.00 13.49 ? 30   GLN H CA  1 
ATOM   483  C C   . GLN B 2  15  ? -18.665 23.077  -49.313 1.00 13.14 ? 30   GLN H C   1 
ATOM   484  O O   . GLN B 2  15  ? -17.732 23.743  -49.766 1.00 12.35 ? 30   GLN H O   1 
ATOM   485  C CB  . GLN B 2  15  ? -19.237 21.466  -51.103 1.00 13.94 ? 30   GLN H CB  1 
ATOM   486  C CG  . GLN B 2  15  ? -19.125 20.117  -50.396 1.00 11.82 ? 30   GLN H CG  1 
ATOM   487  C CD  . GLN B 2  15  ? -20.486 19.499  -50.159 1.00 15.48 ? 30   GLN H CD  1 
ATOM   488  O OE1 . GLN B 2  15  ? -21.396 19.677  -50.964 1.00 18.76 ? 30   GLN H OE1 1 
ATOM   489  N NE2 . GLN B 2  15  ? -20.626 18.760  -49.066 1.00 16.54 ? 30   GLN H NE2 1 
ATOM   490  N N   . VAL B 2  16  ? -18.755 22.748  -48.031 1.00 11.95 ? 31   VAL H N   1 
ATOM   491  C CA  . VAL B 2  16  ? -17.715 23.136  -47.100 1.00 13.19 ? 31   VAL H CA  1 
ATOM   492  C C   . VAL B 2  16  ? -17.198 21.919  -46.345 1.00 14.62 ? 31   VAL H C   1 
ATOM   493  O O   . VAL B 2  16  ? -17.967 21.025  -45.968 1.00 13.75 ? 31   VAL H O   1 
ATOM   494  C CB  . VAL B 2  16  ? -18.226 24.201  -46.096 1.00 13.53 ? 31   VAL H CB  1 
ATOM   495  C CG1 . VAL B 2  16  ? -17.136 24.521  -45.069 1.00 16.92 ? 31   VAL H CG1 1 
ATOM   496  C CG2 . VAL B 2  16  ? -18.630 25.458  -46.851 1.00 13.47 ? 31   VAL H CG2 1 
ATOM   497  N N   A MET B 2  17  ? -15.884 21.898  -46.134 0.03 13.63 ? 32   MET H N   1 
ATOM   498  N N   B MET B 2  17  ? -15.886 21.863  -46.147 0.84 13.45 ? 32   MET H N   1 
ATOM   499  C CA  A MET B 2  17  ? -15.223 20.827  -45.399 0.10 13.62 ? 32   MET H CA  1 
ATOM   500  C CA  B MET B 2  17  ? -15.262 20.752  -45.438 0.90 14.92 ? 32   MET H CA  1 
ATOM   501  C C   A MET B 2  17  ? -14.910 21.331  -44.004 0.01 14.47 ? 32   MET H C   1 
ATOM   502  C C   B MET B 2  17  ? -14.862 21.255  -44.046 0.99 15.40 ? 32   MET H C   1 
ATOM   503  O O   A MET B 2  17  ? -14.280 22.376  -43.844 0.10 14.26 ? 32   MET H O   1 
ATOM   504  O O   B MET B 2  17  ? -14.125 22.236  -43.935 0.67 14.61 ? 32   MET H O   1 
ATOM   505  C CB  A MET B 2  17  ? -13.900 20.432  -46.054 0.10 11.99 ? 32   MET H CB  1 
ATOM   506  C CB  B MET B 2  17  ? -14.032 20.299  -46.228 0.88 14.49 ? 32   MET H CB  1 
ATOM   507  C CG  A MET B 2  17  ? -14.016 19.698  -47.359 0.41 10.14 ? 32   MET H CG  1 
ATOM   508  C CG  B MET B 2  17  ? -13.555 18.895  -45.950 0.53 15.78 ? 32   MET H CG  1 
ATOM   509  S SD  A MET B 2  17  ? -12.420 19.057  -47.893 0.14 6.95  ? 32   MET H SD  1 
ATOM   510  S SD  B MET B 2  17  ? -12.060 18.558  -46.916 0.55 16.39 ? 32   MET H SD  1 
ATOM   511  C CE  A MET B 2  17  ? -12.505 17.378  -47.304 0.22 6.81  ? 32   MET H CE  1 
ATOM   512  C CE  B MET B 2  17  ? -12.704 17.727  -48.300 0.78 17.68 ? 32   MET H CE  1 
ATOM   513  N N   . LEU B 2  18  ? -15.346 20.594  -42.992 1.00 15.12 ? 33   LEU H N   1 
ATOM   514  C CA  . LEU B 2  18  ? -15.057 20.994  -41.613 1.00 17.37 ? 33   LEU H CA  1 
ATOM   515  C C   . LEU B 2  18  ? -13.966 20.110  -41.025 1.00 21.15 ? 33   LEU H C   1 
ATOM   516  O O   . LEU B 2  18  ? -14.053 18.878  -41.092 1.00 21.77 ? 33   LEU H O   1 
ATOM   517  C CB  . LEU B 2  18  ? -16.322 20.909  -40.742 1.00 17.17 ? 33   LEU H CB  1 
ATOM   518  C CG  . LEU B 2  18  ? -16.190 21.281  -39.255 1.00 19.10 ? 33   LEU H CG  1 
ATOM   519  C CD1 . LEU B 2  18  ? -15.682 22.715  -39.115 1.00 19.50 ? 33   LEU H CD1 1 
ATOM   520  C CD2 . LEU B 2  18  ? -17.538 21.138  -38.561 1.00 19.13 ? 33   LEU H CD2 1 
ATOM   521  N N   . PHE B 2  19  ? -12.940 20.746  -40.460 1.00 24.63 ? 34   PHE H N   1 
ATOM   522  C CA  . PHE B 2  19  ? -11.817 20.030  -39.857 1.00 28.95 ? 34   PHE H CA  1 
ATOM   523  C C   . PHE B 2  19  ? -11.590 20.319  -38.390 1.00 32.21 ? 34   PHE H C   1 
ATOM   524  O O   . PHE B 2  19  ? -11.983 21.365  -37.871 1.00 31.61 ? 34   PHE H O   1 
ATOM   525  C CB  . PHE B 2  19  ? -10.507 20.376  -40.552 1.00 28.75 ? 34   PHE H CB  1 
ATOM   526  C CG  . PHE B 2  19  ? -10.385 19.830  -41.923 1.00 28.43 ? 34   PHE H CG  1 
ATOM   527  C CD1 . PHE B 2  19  ? -11.109 20.378  -42.970 1.00 29.35 ? 34   PHE H CD1 1 
ATOM   528  C CD2 . PHE B 2  19  ? -9.538  18.758  -42.175 1.00 28.57 ? 34   PHE H CD2 1 
ATOM   529  C CE1 . PHE B 2  19  ? -10.987 19.862  -44.247 1.00 30.25 ? 34   PHE H CE1 1 
ATOM   530  C CE2 . PHE B 2  19  ? -9.412  18.237  -43.448 1.00 28.64 ? 34   PHE H CE2 1 
ATOM   531  C CZ  . PHE B 2  19  ? -10.134 18.786  -44.486 1.00 29.17 ? 34   PHE H CZ  1 
ATOM   532  N N   . ARG B 2  20  ? -10.926 19.372  -37.738 1.00 36.32 ? 35   ARG H N   1 
ATOM   533  C CA  . ARG B 2  20  ? -10.543 19.502  -36.345 1.00 41.17 ? 35   ARG H CA  1 
ATOM   534  C C   . ARG B 2  20  ? -9.051  19.776  -36.496 1.00 43.91 ? 35   ARG H C   1 
ATOM   535  O O   . ARG B 2  20  ? -8.512  19.626  -37.596 1.00 42.90 ? 35   ARG H O   1 
ATOM   536  C CB  . ARG B 2  20  ? -10.778 18.190  -35.592 1.00 42.88 ? 35   ARG H CB  1 
ATOM   537  C CG  . ARG B 2  20  ? -9.978  17.006  -36.107 1.00 46.58 ? 35   ARG H CG  1 
ATOM   538  C CD  . ARG B 2  20  ? -9.047  16.481  -35.026 1.00 49.85 ? 35   ARG H CD  1 
ATOM   539  N NE  . ARG B 2  20  ? -9.770  16.135  -33.806 1.00 51.75 ? 35   ARG H NE  1 
ATOM   540  C CZ  . ARG B 2  20  ? -9.187  15.753  -32.676 1.00 52.79 ? 35   ARG H CZ  1 
ATOM   541  N NH1 . ARG B 2  20  ? -7.865  15.666  -32.605 1.00 54.72 ? 35   ARG H NH1 1 
ATOM   542  N NH2 . ARG B 2  20  ? -9.925  15.457  -31.615 1.00 52.67 ? 35   ARG H NH2 1 
ATOM   543  N N   . LYS B 2  21  ? -8.375  20.177  -35.426 1.00 47.23 ? 36   LYS H N   1 
ATOM   544  C CA  . LYS B 2  21  ? -6.948  20.457  -35.546 1.00 49.79 ? 36   LYS H CA  1 
ATOM   545  C C   . LYS B 2  21  ? -6.046  19.727  -34.564 1.00 51.19 ? 36   LYS H C   1 
ATOM   546  O O   . LYS B 2  21  ? -6.501  19.201  -33.546 1.00 51.77 ? 36   LYS H O   1 
ATOM   547  C CB  . LYS B 2  21  ? -6.694  21.963  -35.443 1.00 50.50 ? 36   LYS H CB  1 
ATOM   548  C CG  . LYS B 2  21  ? -7.147  22.741  -36.665 1.00 50.94 ? 36   LYS H CG  1 
ATOM   549  C CD  . LYS B 2  21  ? -6.755  24.204  -36.571 1.00 51.70 ? 36   LYS H CD  1 
ATOM   550  C CE  . LYS B 2  21  ? -7.439  24.890  -35.401 1.00 52.09 ? 36   LYS H CE  1 
ATOM   551  N NZ  . LYS B 2  21  ? -7.095  26.336  -35.339 1.00 53.02 ? 36   LYS H NZ  1 
ATOM   552  N N   . SER B 2  22  A -4.757  19.702  -34.898 1.00 52.14 ? 36   SER H N   1 
ATOM   553  C CA  . SER B 2  22  A -3.731  19.057  -34.087 1.00 52.58 ? 36   SER H CA  1 
ATOM   554  C C   . SER B 2  22  A -4.254  17.826  -33.356 1.00 52.69 ? 36   SER H C   1 
ATOM   555  O O   . SER B 2  22  A -4.508  17.868  -32.151 1.00 54.21 ? 36   SER H O   1 
ATOM   556  C CB  . SER B 2  22  A -3.159  20.057  -33.078 1.00 52.76 ? 36   SER H CB  1 
ATOM   557  N N   . PRO B 2  23  ? -4.428  16.710  -34.080 1.00 51.63 ? 37   PRO H N   1 
ATOM   558  C CA  . PRO B 2  23  ? -4.158  16.572  -35.515 1.00 50.22 ? 37   PRO H CA  1 
ATOM   559  C C   . PRO B 2  23  ? -5.325  17.106  -36.338 1.00 49.01 ? 37   PRO H C   1 
ATOM   560  O O   . PRO B 2  23  ? -6.451  17.171  -35.851 1.00 48.85 ? 37   PRO H O   1 
ATOM   561  C CB  . PRO B 2  23  ? -3.994  15.070  -35.679 1.00 50.61 ? 37   PRO H CB  1 
ATOM   562  C CG  . PRO B 2  23  ? -5.032  14.549  -34.734 1.00 51.34 ? 37   PRO H CG  1 
ATOM   563  C CD  . PRO B 2  23  ? -4.822  15.414  -33.500 1.00 51.38 ? 37   PRO H CD  1 
ATOM   564  N N   . GLN B 2  24  ? -5.061  17.490  -37.581 1.00 47.51 ? 38   GLN H N   1 
ATOM   565  C CA  . GLN B 2  24  ? -6.128  17.996  -38.432 1.00 45.35 ? 38   GLN H CA  1 
ATOM   566  C C   . GLN B 2  24  ? -6.647  16.897  -39.346 1.00 42.70 ? 38   GLN H C   1 
ATOM   567  O O   . GLN B 2  24  ? -5.889  16.300  -40.115 1.00 42.85 ? 38   GLN H O   1 
ATOM   568  C CB  . GLN B 2  24  ? -5.646  19.181  -39.274 1.00 46.90 ? 38   GLN H CB  1 
ATOM   569  C CG  . GLN B 2  24  ? -4.531  18.862  -40.254 1.00 48.96 ? 38   GLN H CG  1 
ATOM   570  C CD  . GLN B 2  24  ? -4.346  19.955  -41.293 1.00 50.58 ? 38   GLN H CD  1 
ATOM   571  O OE1 . GLN B 2  24  ? -3.394  19.930  -42.073 1.00 51.09 ? 38   GLN H OE1 1 
ATOM   572  N NE2 . GLN B 2  24  ? -5.265  20.915  -41.314 1.00 50.29 ? 38   GLN H NE2 1 
ATOM   573  N N   . GLU B 2  25  ? -7.942  16.619  -39.248 1.00 38.38 ? 39   GLU H N   1 
ATOM   574  C CA  . GLU B 2  25  ? -8.557  15.600  -40.087 1.00 34.24 ? 39   GLU H CA  1 
ATOM   575  C C   . GLU B 2  25  ? -10.010 15.960  -40.359 1.00 29.97 ? 39   GLU H C   1 
ATOM   576  O O   . GLU B 2  25  ? -10.613 16.740  -39.619 1.00 29.70 ? 39   GLU H O   1 
ATOM   577  C CB  . GLU B 2  25  ? -8.473  14.216  -39.427 1.00 36.27 ? 39   GLU H CB  1 
ATOM   578  C CG  . GLU B 2  25  ? -9.272  14.056  -38.143 1.00 37.48 ? 39   GLU H CG  1 
ATOM   579  C CD  . GLU B 2  25  ? -9.288  12.612  -37.647 1.00 39.02 ? 39   GLU H CD  1 
ATOM   580  O OE1 . GLU B 2  25  ? -9.934  12.341  -36.614 1.00 39.48 ? 39   GLU H OE1 1 
ATOM   581  O OE2 . GLU B 2  25  ? -8.655  11.748  -38.291 1.00 40.07 ? 39   GLU H OE2 1 
ATOM   582  N N   A LEU B 2  26  ? -10.561 15.413  -41.434 0.48 28.25 ? 40   LEU H N   1 
ATOM   583  N N   B LEU B 2  26  ? -10.564 15.370  -41.413 0.48 28.64 ? 40   LEU H N   1 
ATOM   584  C CA  A LEU B 2  26  ? -11.939 15.701  -41.811 0.03 25.33 ? 40   LEU H CA  1 
ATOM   585  C CA  B LEU B 2  26  ? -11.952 15.605  -41.789 0.97 26.04 ? 40   LEU H CA  1 
ATOM   586  C C   A LEU B 2  26  ? -12.927 15.248  -40.743 0.13 23.56 ? 40   LEU H C   1 
ATOM   587  C C   B LEU B 2  26  ? -12.860 15.301  -40.605 0.61 24.27 ? 40   LEU H C   1 
ATOM   588  O O   A LEU B 2  26  ? -12.964 14.075  -40.371 0.11 23.23 ? 40   LEU H O   1 
ATOM   589  O O   B LEU B 2  26  ? -12.739 14.255  -39.969 0.89 22.89 ? 40   LEU H O   1 
ATOM   590  C CB  A LEU B 2  26  ? -12.266 15.034  -43.151 0.43 25.36 ? 40   LEU H CB  1 
ATOM   591  C CB  B LEU B 2  26  ? -12.345 14.716  -42.971 0.57 26.72 ? 40   LEU H CB  1 
ATOM   592  C CG  A LEU B 2  26  ? -13.618 15.365  -43.795 0.35 24.82 ? 40   LEU H CG  1 
ATOM   593  C CG  B LEU B 2  26  ? -13.811 14.820  -43.402 0.50 26.40 ? 40   LEU H CG  1 
ATOM   594  C CD1 A LEU B 2  26  ? -13.585 14.972  -45.259 0.32 24.16 ? 40   LEU H CD1 1 
ATOM   595  C CD1 B LEU B 2  26  ? -14.101 16.238  -43.867 0.68 27.09 ? 40   LEU H CD1 1 
ATOM   596  C CD2 A LEU B 2  26  ? -14.746 14.649  -43.069 0.27 24.68 ? 40   LEU H CD2 1 
ATOM   597  C CD2 B LEU B 2  26  ? -14.104 13.820  -44.509 0.37 26.70 ? 40   LEU H CD2 1 
ATOM   598  N N   A LEU B 2  27  ? -13.727 16.191  -40.255 0.44 21.23 ? 41   LEU H N   1 
ATOM   599  N N   B LEU B 2  27  ? -13.774 16.219  -40.316 0.53 22.16 ? 41   LEU H N   1 
ATOM   600  C CA  A LEU B 2  27  ? -14.727 15.903  -39.235 0.04 18.81 ? 41   LEU H CA  1 
ATOM   601  C CA  B LEU B 2  27  ? -14.696 16.049  -39.204 0.96 19.96 ? 41   LEU H CA  1 
ATOM   602  C C   A LEU B 2  27  ? -16.114 15.742  -39.829 0.60 17.12 ? 41   LEU H C   1 
ATOM   603  C C   B LEU B 2  27  ? -16.124 15.865  -39.697 0.40 18.03 ? 41   LEU H C   1 
ATOM   604  O O   A LEU B 2  27  ? -16.804 14.756  -39.572 0.25 16.40 ? 41   LEU H O   1 
ATOM   605  O O   B LEU B 2  27  ? -16.844 14.976  -39.247 0.61 16.77 ? 41   LEU H O   1 
ATOM   606  C CB  A LEU B 2  27  ? -14.803 17.034  -38.205 0.36 19.56 ? 41   LEU H CB  1 
ATOM   607  C CB  B LEU B 2  27  ? -14.638 17.276  -38.294 0.64 22.04 ? 41   LEU H CB  1 
ATOM   608  C CG  A LEU B 2  27  ? -13.703 17.246  -37.169 0.21 19.23 ? 41   LEU H CG  1 
ATOM   609  C CG  B LEU B 2  27  ? -15.486 17.224  -37.025 0.79 23.36 ? 41   LEU H CG  1 
ATOM   610  C CD1 A LEU B 2  27  ? -14.051 18.464  -36.334 0.31 19.60 ? 41   LEU H CD1 1 
ATOM   611  C CD1 B LEU B 2  27  ? -14.949 16.146  -36.094 0.22 23.34 ? 41   LEU H CD1 1 
ATOM   612  C CD2 A LEU B 2  27  ? -13.569 16.022  -36.286 0.35 19.42 ? 41   LEU H CD2 1 
ATOM   613  C CD2 B LEU B 2  27  ? -15.453 18.580  -36.338 0.65 23.51 ? 41   LEU H CD2 1 
ATOM   614  N N   . CYS B 2  28  ? -16.515 16.722  -40.632 1.00 15.17 ? 42   CYS H N   1 
ATOM   615  C CA  . CYS B 2  28  ? -17.854 16.716  -41.198 1.00 14.43 ? 42   CYS H CA  1 
ATOM   616  C C   . CYS B 2  28  ? -17.965 17.557  -42.446 1.00 13.79 ? 42   CYS H C   1 
ATOM   617  O O   . CYS B 2  28  ? -17.003 18.181  -42.892 1.00 13.66 ? 42   CYS H O   1 
ATOM   618  C CB  . CYS B 2  28  ? -18.819 17.332  -40.194 1.00 15.51 ? 42   CYS H CB  1 
ATOM   619  S SG  . CYS B 2  28  ? -19.464 16.256  -38.889 1.00 16.58 ? 42   CYS H SG  1 
ATOM   620  N N   . GLY B 2  29  ? -19.183 17.574  -42.976 1.00 12.50 ? 43   GLY H N   1 
ATOM   621  C CA  . GLY B 2  29  ? -19.506 18.388  -44.128 1.00 13.66 ? 43   GLY H CA  1 
ATOM   622  C C   . GLY B 2  29  ? -20.155 19.637  -43.546 1.00 12.41 ? 43   GLY H C   1 
ATOM   623  O O   . GLY B 2  29  ? -20.400 19.711  -42.333 1.00 11.38 ? 43   GLY H O   1 
ATOM   624  N N   . ALA B 2  30  ? -20.433 20.608  -44.408 1.00 12.66 ? 44   ALA H N   1 
ATOM   625  C CA  . ALA B 2  30  ? -21.043 21.876  -44.015 1.00 12.16 ? 44   ALA H CA  1 
ATOM   626  C C   . ALA B 2  30  ? -21.446 22.558  -45.312 1.00 11.20 ? 44   ALA H C   1 
ATOM   627  O O   . ALA B 2  30  ? -21.152 22.052  -46.394 1.00 11.04 ? 44   ALA H O   1 
ATOM   628  C CB  . ALA B 2  30  ? -20.032 22.732  -43.247 1.00 12.56 ? 44   ALA H CB  1 
ATOM   629  N N   A SER B 2  31  ? -22.099 23.709  -45.216 0.29 9.76  ? 45   SER H N   1 
ATOM   630  N N   B SER B 2  31  ? -22.115 23.705  -45.206 0.63 10.55 ? 45   SER H N   1 
ATOM   631  C CA  A SER B 2  31  ? -22.517 24.420  -46.414 0.15 8.73  ? 45   SER H CA  1 
ATOM   632  C CA  B SER B 2  31  ? -22.574 24.423  -46.389 0.85 10.58 ? 45   SER H CA  1 
ATOM   633  C C   A SER B 2  31  ? -22.320 25.918  -46.251 0.12 9.23  ? 45   SER H C   1 
ATOM   634  C C   B SER B 2  31  ? -22.397 25.939  -46.253 0.88 10.88 ? 45   SER H C   1 
ATOM   635  O O   A SER B 2  31  ? -22.350 26.436  -45.138 0.39 7.38  ? 45   SER H O   1 
ATOM   636  O O   B SER B 2  31  ? -22.515 26.486  -45.159 0.37 9.28  ? 45   SER H O   1 
ATOM   637  C CB  A SER B 2  31  ? -23.985 24.129  -46.711 0.15 8.70  ? 45   SER H CB  1 
ATOM   638  C CB  B SER B 2  31  ? -24.047 24.087  -46.648 0.85 13.91 ? 45   SER H CB  1 
ATOM   639  O OG  A SER B 2  31  ? -24.800 24.595  -45.655 0.46 3.86  ? 45   SER H OG  1 
ATOM   640  O OG  B SER B 2  31  ? -24.482 24.602  -47.894 0.17 12.13 ? 45   SER H OG  1 
ATOM   641  N N   . LEU B 2  32  ? -22.119 26.602  -47.372 1.00 10.38 ? 46   LEU H N   1 
ATOM   642  C CA  . LEU B 2  32  ? -21.914 28.050  -47.379 1.00 10.48 ? 46   LEU H CA  1 
ATOM   643  C C   . LEU B 2  32  ? -23.223 28.752  -47.722 1.00 10.85 ? 46   LEU H C   1 
ATOM   644  O O   . LEU B 2  32  ? -23.788 28.511  -48.784 1.00 10.88 ? 46   LEU H O   1 
ATOM   645  C CB  . LEU B 2  32  ? -20.862 28.407  -48.433 1.00 11.82 ? 46   LEU H CB  1 
ATOM   646  C CG  . LEU B 2  32  ? -20.364 29.852  -48.424 1.00 12.86 ? 46   LEU H CG  1 
ATOM   647  C CD1 . LEU B 2  32  ? -19.520 30.062  -47.194 1.00 14.04 ? 46   LEU H CD1 1 
ATOM   648  C CD2 . LEU B 2  32  ? -19.564 30.135  -49.691 1.00 14.22 ? 46   LEU H CD2 1 
ATOM   649  N N   . ILE B 2  33  ? -23.696 29.639  -46.847 1.00 11.16 ? 47   ILE H N   1 
ATOM   650  C CA  . ILE B 2  33  ? -24.942 30.346  -47.128 1.00 10.95 ? 47   ILE H CA  1 
ATOM   651  C C   . ILE B 2  33  ? -24.737 31.838  -47.406 1.00 11.29 ? 47   ILE H C   1 
ATOM   652  O O   . ILE B 2  33  ? -25.675 32.533  -47.788 1.00 11.90 ? 47   ILE H O   1 
ATOM   653  C CB  . ILE B 2  33  ? -25.986 30.157  -45.993 1.00 10.38 ? 47   ILE H CB  1 
ATOM   654  C CG1 . ILE B 2  33  ? -25.473 30.731  -44.670 1.00 12.74 ? 47   ILE H CG1 1 
ATOM   655  C CG2 . ILE B 2  33  ? -26.301 28.657  -45.829 1.00 11.91 ? 47   ILE H CG2 1 
ATOM   656  C CD1 . ILE B 2  33  ? -26.509 30.681  -43.545 1.00 13.69 ? 47   ILE H CD1 1 
ATOM   657  N N   . SER B 2  34  ? -23.506 32.313  -47.215 1.00 11.97 ? 48   SER H N   1 
ATOM   658  C CA  . SER B 2  34  ? -23.140 33.712  -47.498 1.00 11.79 ? 48   SER H CA  1 
ATOM   659  C C   . SER B 2  34  ? -21.628 33.759  -47.434 1.00 12.00 ? 48   SER H C   1 
ATOM   660  O O   . SER B 2  34  ? -20.990 32.732  -47.223 1.00 15.86 ? 48   SER H O   1 
ATOM   661  C CB  . SER B 2  34  ? -23.724 34.682  -46.464 1.00 10.79 ? 48   SER H CB  1 
ATOM   662  O OG  . SER B 2  34  ? -23.044 34.621  -45.226 1.00 12.11 ? 48   SER H OG  1 
ATOM   663  N N   . ASP B 2  35  ? -21.026 34.930  -47.611 1.00 12.77 ? 49   ASP H N   1 
ATOM   664  C CA  . ASP B 2  35  ? -19.577 34.951  -47.527 1.00 14.00 ? 49   ASP H CA  1 
ATOM   665  C C   . ASP B 2  35  ? -19.074 34.982  -46.083 1.00 12.73 ? 49   ASP H C   1 
ATOM   666  O O   . ASP B 2  35  ? -17.870 34.974  -45.848 1.00 14.99 ? 49   ASP H O   1 
ATOM   667  C CB  . ASP B 2  35  ? -18.994 36.119  -48.347 1.00 16.13 ? 49   ASP H CB  1 
ATOM   668  C CG  . ASP B 2  35  ? -19.285 37.483  -47.756 1.00 17.63 ? 49   ASP H CG  1 
ATOM   669  O OD1 . ASP B 2  35  ? -20.124 37.607  -46.847 1.00 17.50 ? 49   ASP H OD1 1 
ATOM   670  O OD2 . ASP B 2  35  ? -18.659 38.454  -48.239 1.00 21.54 ? 49   ASP H OD2 1 
ATOM   671  N N   A ARG B 2  36  ? -20.017 35.014  -45.142 0.12 13.02 ? 50   ARG H N   1 
ATOM   672  N N   B ARG B 2  36  ? -19.974 34.966  -45.100 0.88 13.65 ? 50   ARG H N   1 
ATOM   673  C CA  A ARG B 2  36  ? -19.712 35.116  -43.720 0.48 11.96 ? 50   ARG H CA  1 
ATOM   674  C CA  B ARG B 2  36  ? -19.513 34.950  -43.717 0.52 12.97 ? 50   ARG H CA  1 
ATOM   675  C C   A ARG B 2  36  ? -20.333 34.034  -42.827 0.01 12.18 ? 50   ARG H C   1 
ATOM   676  C C   B ARG B 2  36  ? -20.160 33.855  -42.868 0.99 12.60 ? 50   ARG H C   1 
ATOM   677  O O   A ARG B 2  36  ? -20.030 33.960  -41.636 0.10 11.95 ? 50   ARG H O   1 
ATOM   678  O O   B ARG B 2  36  ? -19.716 33.601  -41.747 0.83 11.30 ? 50   ARG H O   1 
ATOM   679  C CB  A ARG B 2  36  ? -20.172 36.500  -43.240 0.45 12.70 ? 50   ARG H CB  1 
ATOM   680  C CB  B ARG B 2  36  ? -19.722 36.319  -43.050 0.35 15.02 ? 50   ARG H CB  1 
ATOM   681  C CG  A ARG B 2  36  ? -19.789 36.875  -41.829 0.33 12.06 ? 50   ARG H CG  1 
ATOM   682  C CG  B ARG B 2  36  ? -21.163 36.668  -42.765 0.52 16.52 ? 50   ARG H CG  1 
ATOM   683  C CD  A ARG B 2  36  ? -20.544 38.128  -41.398 0.35 10.38 ? 50   ARG H CD  1 
ATOM   684  C CD  B ARG B 2  36  ? -21.287 37.993  -42.019 0.65 17.35 ? 50   ARG H CD  1 
ATOM   685  N NE  A ARG B 2  36  ? -20.451 39.203  -42.383 0.31 9.74  ? 50   ARG H NE  1 
ATOM   686  N NE  B ARG B 2  36  ? -20.765 39.120  -42.788 0.55 17.61 ? 50   ARG H NE  1 
ATOM   687  C CZ  A ARG B 2  36  ? -21.128 40.347  -42.304 0.10 9.47  ? 50   ARG H CZ  1 
ATOM   688  C CZ  B ARG B 2  36  ? -21.036 40.393  -42.516 0.81 18.01 ? 50   ARG H CZ  1 
ATOM   689  N NH1 A ARG B 2  36  ? -20.989 41.274  -43.244 0.35 9.05  ? 50   ARG H NH1 1 
ATOM   690  N NH1 B ARG B 2  36  ? -20.520 41.360  -43.263 0.29 17.85 ? 50   ARG H NH1 1 
ATOM   691  N NH2 A ARG B 2  36  ? -21.949 40.564  -41.284 0.21 8.82  ? 50   ARG H NH2 1 
ATOM   692  N NH2 B ARG B 2  36  ? -21.836 40.698  -41.500 0.67 17.51 ? 50   ARG H NH2 1 
ATOM   693  N N   . TRP B 2  37  ? -21.193 33.196  -43.396 1.00 11.58 ? 51   TRP H N   1 
ATOM   694  C CA  . TRP B 2  37  ? -21.871 32.143  -42.628 1.00 12.11 ? 51   TRP H CA  1 
ATOM   695  C C   . TRP B 2  37  ? -21.880 30.745  -43.244 1.00 11.16 ? 51   TRP H C   1 
ATOM   696  O O   . TRP B 2  37  ? -22.103 30.579  -44.445 1.00 11.61 ? 51   TRP H O   1 
ATOM   697  C CB  . TRP B 2  37  ? -23.317 32.548  -42.335 1.00 11.11 ? 51   TRP H CB  1 
ATOM   698  C CG  . TRP B 2  37  ? -23.450 33.614  -41.289 1.00 11.34 ? 51   TRP H CG  1 
ATOM   699  C CD1 . TRP B 2  37  ? -23.698 34.940  -41.498 1.00 14.40 ? 51   TRP H CD1 1 
ATOM   700  C CD2 . TRP B 2  37  ? -23.345 33.444  -39.866 1.00 12.20 ? 51   TRP H CD2 1 
ATOM   701  N NE1 . TRP B 2  37  ? -23.761 35.604  -40.295 1.00 13.38 ? 51   TRP H NE1 1 
ATOM   702  C CE2 . TRP B 2  37  ? -23.547 34.714  -39.278 1.00 13.86 ? 51   TRP H CE2 1 
ATOM   703  C CE3 . TRP B 2  37  ? -23.101 32.345  -39.031 1.00 11.17 ? 51   TRP H CE3 1 
ATOM   704  C CZ2 . TRP B 2  37  ? -23.512 34.915  -37.892 1.00 13.49 ? 51   TRP H CZ2 1 
ATOM   705  C CZ3 . TRP B 2  37  ? -23.064 32.545  -37.650 1.00 12.35 ? 51   TRP H CZ3 1 
ATOM   706  C CH2 . TRP B 2  37  ? -23.270 33.824  -37.096 1.00 15.39 ? 51   TRP H CH2 1 
ATOM   707  N N   . VAL B 2  38  ? -21.665 29.756  -42.381 1.00 11.49 ? 52   VAL H N   1 
ATOM   708  C CA  . VAL B 2  38  ? -21.632 28.347  -42.766 1.00 11.91 ? 52   VAL H CA  1 
ATOM   709  C C   . VAL B 2  38  ? -22.560 27.548  -41.857 1.00 12.26 ? 52   VAL H C   1 
ATOM   710  O O   . VAL B 2  38  ? -22.606 27.772  -40.648 1.00 12.30 ? 52   VAL H O   1 
ATOM   711  C CB  . VAL B 2  38  ? -20.195 27.775  -42.632 1.00 13.96 ? 52   VAL H CB  1 
ATOM   712  C CG1 . VAL B 2  38  ? -20.196 26.258  -42.873 1.00 12.35 ? 52   VAL H CG1 1 
ATOM   713  C CG2 . VAL B 2  38  ? -19.265 28.460  -43.629 1.00 14.10 ? 52   VAL H CG2 1 
ATOM   714  N N   . LEU B 2  39  ? -23.297 26.610  -42.446 1.00 12.85 ? 53   LEU H N   1 
ATOM   715  C CA  . LEU B 2  39  ? -24.212 25.750  -41.698 1.00 12.86 ? 53   LEU H CA  1 
ATOM   716  C C   . LEU B 2  39  ? -23.625 24.353  -41.576 1.00 12.68 ? 53   LEU H C   1 
ATOM   717  O O   . LEU B 2  39  ? -22.955 23.883  -42.493 1.00 12.11 ? 53   LEU H O   1 
ATOM   718  C CB  . LEU B 2  39  ? -25.543 25.603  -42.434 1.00 12.80 ? 53   LEU H CB  1 
ATOM   719  C CG  . LEU B 2  39  ? -26.710 26.554  -42.209 1.00 17.10 ? 53   LEU H CG  1 
ATOM   720  C CD1 . LEU B 2  39  ? -27.854 26.155  -43.138 1.00 16.27 ? 53   LEU H CD1 1 
ATOM   721  C CD2 . LEU B 2  39  ? -27.150 26.485  -40.751 1.00 14.96 ? 53   LEU H CD2 1 
ATOM   722  N N   . THR B 2  40  ? -23.871 23.702  -40.445 1.00 11.74 ? 54   THR H N   1 
ATOM   723  C CA  . THR B 2  40  ? -23.424 22.323  -40.258 1.00 10.40 ? 54   THR H CA  1 
ATOM   724  C C   . THR B 2  40  ? -24.337 21.663  -39.228 1.00 12.37 ? 54   THR H C   1 
ATOM   725  O O   . THR B 2  40  ? -25.353 22.239  -38.843 1.00 12.12 ? 54   THR H O   1 
ATOM   726  C CB  . THR B 2  40  ? -21.941 22.254  -39.808 1.00 12.17 ? 54   THR H CB  1 
ATOM   727  O OG1 . THR B 2  40  ? -21.486 20.891  -39.886 1.00 12.56 ? 54   THR H OG1 1 
ATOM   728  C CG2 . THR B 2  40  ? -21.790 22.740  -38.374 1.00 10.22 ? 54   THR H CG2 1 
ATOM   729  N N   . ALA B 2  41  ? -24.009 20.438  -38.821 1.00 12.16 ? 55   ALA H N   1 
ATOM   730  C CA  . ALA B 2  41  ? -24.815 19.732  -37.836 1.00 11.96 ? 55   ALA H CA  1 
ATOM   731  C C   . ALA B 2  41  ? -24.249 19.917  -36.436 1.00 12.24 ? 55   ALA H C   1 
ATOM   732  O O   . ALA B 2  41  ? -23.035 19.948  -36.247 1.00 12.94 ? 55   ALA H O   1 
ATOM   733  C CB  . ALA B 2  41  ? -24.869 18.241  -38.169 1.00 12.40 ? 55   ALA H CB  1 
ATOM   734  N N   . ALA B 2  42  ? -25.138 20.022  -35.456 1.00 11.97 ? 56   ALA H N   1 
ATOM   735  C CA  . ALA B 2  42  ? -24.724 20.176  -34.070 1.00 12.94 ? 56   ALA H CA  1 
ATOM   736  C C   . ALA B 2  42  ? -23.910 18.970  -33.596 1.00 13.35 ? 56   ALA H C   1 
ATOM   737  O O   . ALA B 2  42  ? -22.932 19.138  -32.870 1.00 14.47 ? 56   ALA H O   1 
ATOM   738  C CB  . ALA B 2  42  ? -25.946 20.365  -33.174 1.00 14.45 ? 56   ALA H CB  1 
ATOM   739  N N   . HIS B 2  43  ? -24.285 17.757  -34.007 1.00 15.71 ? 57   HIS H N   1 
ATOM   740  C CA  . HIS B 2  43  ? -23.539 16.600  -33.529 1.00 15.90 ? 57   HIS H CA  1 
ATOM   741  C C   . HIS B 2  43  ? -22.119 16.489  -34.075 1.00 16.78 ? 57   HIS H C   1 
ATOM   742  O O   . HIS B 2  43  ? -21.345 15.641  -33.636 1.00 16.47 ? 57   HIS H O   1 
ATOM   743  C CB  . HIS B 2  43  ? -24.337 15.278  -33.707 1.00 14.86 ? 57   HIS H CB  1 
ATOM   744  C CG  . HIS B 2  43  ? -24.220 14.631  -35.054 1.00 15.59 ? 57   HIS H CG  1 
ATOM   745  N ND1 . HIS B 2  43  ? -25.141 14.830  -36.059 1.00 15.87 ? 57   HIS H ND1 1 
ATOM   746  C CD2 . HIS B 2  43  ? -23.355 13.697  -35.519 1.00 15.28 ? 57   HIS H CD2 1 
ATOM   747  C CE1 . HIS B 2  43  ? -24.855 14.041  -37.081 1.00 17.13 ? 57   HIS H CE1 1 
ATOM   748  N NE2 . HIS B 2  43  ? -23.776 13.342  -36.777 1.00 17.45 ? 57   HIS H NE2 1 
ATOM   749  N N   . CYS B 2  44  ? -21.769 17.362  -35.017 1.00 15.40 ? 58   CYS H N   1 
ATOM   750  C CA  . CYS B 2  44  ? -20.414 17.386  -35.541 1.00 15.90 ? 58   CYS H CA  1 
ATOM   751  C C   . CYS B 2  44  ? -19.522 18.070  -34.513 1.00 16.82 ? 58   CYS H C   1 
ATOM   752  O O   . CYS B 2  44  ? -18.316 17.832  -34.456 1.00 18.36 ? 58   CYS H O   1 
ATOM   753  C CB  . CYS B 2  44  ? -20.350 18.209  -36.821 1.00 17.26 ? 58   CYS H CB  1 
ATOM   754  S SG  . CYS B 2  44  ? -21.048 17.324  -38.227 1.00 15.02 ? 58   CYS H SG  1 
ATOM   755  N N   . LEU B 2  45  ? -20.133 18.920  -33.699 1.00 16.89 ? 59   LEU H N   1 
ATOM   756  C CA  . LEU B 2  45  ? -19.398 19.714  -32.721 1.00 17.80 ? 59   LEU H CA  1 
ATOM   757  C C   . LEU B 2  45  ? -19.568 19.388  -31.251 1.00 18.48 ? 59   LEU H C   1 
ATOM   758  O O   . LEU B 2  45  ? -18.641 19.567  -30.463 1.00 20.27 ? 59   LEU H O   1 
ATOM   759  C CB  . LEU B 2  45  ? -19.778 21.185  -32.893 1.00 18.11 ? 59   LEU H CB  1 
ATOM   760  C CG  . LEU B 2  45  ? -19.720 21.764  -34.305 1.00 16.92 ? 59   LEU H CG  1 
ATOM   761  C CD1 . LEU B 2  45  ? -20.372 23.147  -34.322 1.00 19.42 ? 59   LEU H CD1 1 
ATOM   762  C CD2 . LEU B 2  45  ? -18.281 21.827  -34.752 1.00 18.92 ? 59   LEU H CD2 1 
ATOM   763  N N   . LEU B 2  46  ? -20.749 18.919  -30.878 1.00 17.75 ? 60   LEU H N   1 
ATOM   764  C CA  . LEU B 2  46  ? -21.030 18.697  -29.472 1.00 18.25 ? 60   LEU H CA  1 
ATOM   765  C C   . LEU B 2  46  ? -21.746 17.414  -29.105 1.00 18.57 ? 60   LEU H C   1 
ATOM   766  O O   . LEU B 2  46  ? -22.766 17.067  -29.689 1.00 17.41 ? 60   LEU H O   1 
ATOM   767  C CB  . LEU B 2  46  ? -21.852 19.885  -28.963 1.00 18.84 ? 60   LEU H CB  1 
ATOM   768  C CG  . LEU B 2  46  ? -22.393 19.920  -27.533 1.00 20.60 ? 60   LEU H CG  1 
ATOM   769  C CD1 . LEU B 2  46  ? -21.250 20.139  -26.561 1.00 22.50 ? 60   LEU H CD1 1 
ATOM   770  C CD2 . LEU B 2  46  ? -23.416 21.041  -27.401 1.00 19.94 ? 60   LEU H CD2 1 
ATOM   771  N N   . TYR B 2  47  A -21.191 16.717  -28.119 1.00 18.73 ? 60   TYR H N   1 
ATOM   772  C CA  . TYR B 2  47  A -21.791 15.502  -27.595 1.00 20.35 ? 60   TYR H CA  1 
ATOM   773  C C   . TYR B 2  47  A -21.184 15.265  -26.215 1.00 21.21 ? 60   TYR H C   1 
ATOM   774  O O   . TYR B 2  47  A -20.142 14.626  -26.080 1.00 23.75 ? 60   TYR H O   1 
ATOM   775  C CB  . TYR B 2  47  A -21.534 14.295  -28.493 1.00 20.90 ? 60   TYR H CB  1 
ATOM   776  C CG  . TYR B 2  47  A -22.390 13.117  -28.085 1.00 19.73 ? 60   TYR H CG  1 
ATOM   777  C CD1 . TYR B 2  47  A -23.777 13.229  -28.044 1.00 20.08 ? 60   TYR H CD1 1 
ATOM   778  C CD2 . TYR B 2  47  A -21.816 11.908  -27.690 1.00 24.03 ? 60   TYR H CD2 1 
ATOM   779  C CE1 . TYR B 2  47  A -24.577 12.172  -27.616 1.00 22.43 ? 60   TYR H CE1 1 
ATOM   780  C CE2 . TYR B 2  47  A -22.611 10.840  -27.258 1.00 23.47 ? 60   TYR H CE2 1 
ATOM   781  C CZ  . TYR B 2  47  A -23.987 10.981  -27.223 1.00 23.70 ? 60   TYR H CZ  1 
ATOM   782  O OH  . TYR B 2  47  A -24.784 9.941   -26.791 1.00 25.33 ? 60   TYR H OH  1 
ATOM   783  N N   . PRO B 2  48  B -21.835 15.799  -25.172 1.00 22.40 ? 60   PRO H N   1 
ATOM   784  C CA  . PRO B 2  48  B -21.413 15.691  -23.772 1.00 23.47 ? 60   PRO H CA  1 
ATOM   785  C C   . PRO B 2  48  B -20.974 14.307  -23.284 1.00 24.21 ? 60   PRO H C   1 
ATOM   786  O O   . PRO B 2  48  B -19.950 14.184  -22.616 1.00 26.52 ? 60   PRO H O   1 
ATOM   787  C CB  . PRO B 2  48  B -22.620 16.232  -23.014 1.00 24.17 ? 60   PRO H CB  1 
ATOM   788  C CG  . PRO B 2  48  B -23.103 17.320  -23.938 1.00 23.26 ? 60   PRO H CG  1 
ATOM   789  C CD  . PRO B 2  48  B -23.050 16.628  -25.288 1.00 22.21 ? 60   PRO H CD  1 
ATOM   790  N N   . PRO B 2  49  C -21.738 13.250  -23.607 1.00 24.41 ? 60   PRO H N   1 
ATOM   791  C CA  . PRO B 2  49  C -21.344 11.911  -23.152 1.00 25.76 ? 60   PRO H CA  1 
ATOM   792  C C   . PRO B 2  49  C -19.923 11.497  -23.544 1.00 27.29 ? 60   PRO H C   1 
ATOM   793  O O   . PRO B 2  49  C -19.280 10.723  -22.832 1.00 27.77 ? 60   PRO H O   1 
ATOM   794  C CB  . PRO B 2  49  C -22.405 11.012  -23.778 1.00 25.07 ? 60   PRO H CB  1 
ATOM   795  C CG  . PRO B 2  49  C -23.611 11.881  -23.761 1.00 24.96 ? 60   PRO H CG  1 
ATOM   796  C CD  . PRO B 2  49  C -23.062 13.208  -24.249 1.00 23.66 ? 60   PRO H CD  1 
ATOM   797  N N   . TRP B 2  50  D -19.439 12.004  -24.675 1.00 26.38 ? 60   TRP H N   1 
ATOM   798  C CA  . TRP B 2  50  D -18.092 11.686  -25.151 1.00 26.60 ? 60   TRP H CA  1 
ATOM   799  C C   . TRP B 2  50  D -17.147 12.860  -24.909 1.00 25.15 ? 60   TRP H C   1 
ATOM   800  O O   . TRP B 2  50  D -16.014 12.861  -25.387 1.00 26.20 ? 60   TRP H O   1 
ATOM   801  C CB  . TRP B 2  50  D -18.106 11.392  -26.656 1.00 26.57 ? 60   TRP H CB  1 
ATOM   802  C CG  . TRP B 2  50  D -18.834 10.148  -27.076 1.00 29.70 ? 60   TRP H CG  1 
ATOM   803  C CD1 . TRP B 2  50  D -19.570 9.312   -26.286 1.00 29.98 ? 60   TRP H CD1 1 
ATOM   804  C CD2 . TRP B 2  50  D -18.915 9.619   -28.405 1.00 29.27 ? 60   TRP H CD2 1 
ATOM   805  N NE1 . TRP B 2  50  D -20.108 8.295   -27.043 1.00 30.00 ? 60   TRP H NE1 1 
ATOM   806  C CE2 . TRP B 2  50  D -19.721 8.461   -28.347 1.00 30.20 ? 60   TRP H CE2 1 
ATOM   807  C CE3 . TRP B 2  50  D -18.387 10.013  -29.642 1.00 30.78 ? 60   TRP H CE3 1 
ATOM   808  C CZ2 . TRP B 2  50  D -20.013 7.690   -29.480 1.00 29.97 ? 60   TRP H CZ2 1 
ATOM   809  C CZ3 . TRP B 2  50  D -18.677 9.245   -30.770 1.00 30.09 ? 60   TRP H CZ3 1 
ATOM   810  C CH2 . TRP B 2  50  D -19.483 8.098   -30.678 1.00 28.48 ? 60   TRP H CH2 1 
ATOM   811  N N   . ASP B 2  51  E -17.609 13.852  -24.158 1.00 25.71 ? 60   ASP H N   1 
ATOM   812  C CA  . ASP B 2  51  E -16.811 15.043  -23.910 1.00 25.58 ? 60   ASP H CA  1 
ATOM   813  C C   . ASP B 2  51  E -16.389 15.679  -25.231 1.00 24.91 ? 60   ASP H C   1 
ATOM   814  O O   . ASP B 2  51  E -15.291 16.226  -25.346 1.00 24.39 ? 60   ASP H O   1 
ATOM   815  C CB  . ASP B 2  51  E -15.569 14.725  -23.073 1.00 27.99 ? 60   ASP H CB  1 
ATOM   816  C CG  . ASP B 2  51  E -15.838 14.813  -21.586 1.00 30.51 ? 60   ASP H CG  1 
ATOM   817  O OD1 . ASP B 2  51  E -16.397 15.841  -21.147 1.00 33.86 ? 60   ASP H OD1 1 
ATOM   818  O OD2 . ASP B 2  51  E -15.489 13.863  -20.855 1.00 30.23 ? 60   ASP H OD2 1 
ATOM   819  N N   . LYS B 2  52  F -17.258 15.587  -26.236 1.00 23.28 ? 60   LYS H N   1 
ATOM   820  C CA  . LYS B 2  52  F -16.969 16.199  -27.527 1.00 23.22 ? 60   LYS H CA  1 
ATOM   821  C C   . LYS B 2  52  F -17.504 17.622  -27.464 1.00 23.37 ? 60   LYS H C   1 
ATOM   822  O O   . LYS B 2  52  F -18.698 17.839  -27.246 1.00 21.33 ? 60   LYS H O   1 
ATOM   823  C CB  . LYS B 2  52  F -17.657 15.453  -28.677 1.00 23.51 ? 60   LYS H CB  1 
ATOM   824  C CG  . LYS B 2  52  F -17.428 16.132  -30.038 1.00 22.48 ? 60   LYS H CG  1 
ATOM   825  C CD  . LYS B 2  52  F -18.303 15.557  -31.147 1.00 24.40 ? 60   LYS H CD  1 
ATOM   826  C CE  . LYS B 2  52  F -17.942 14.120  -31.474 1.00 24.64 ? 60   LYS H CE  1 
ATOM   827  N NZ  . LYS B 2  52  F -18.708 13.637  -32.664 1.00 28.17 ? 60   LYS H NZ  1 
ATOM   828  N N   . ASN B 2  53  G -16.618 18.591  -27.646 1.00 26.52 ? 60   ASN H N   1 
ATOM   829  C CA  . ASN B 2  53  G -17.015 19.988  -27.596 1.00 29.01 ? 60   ASN H CA  1 
ATOM   830  C C   . ASN B 2  53  G -16.034 20.844  -28.380 1.00 30.47 ? 60   ASN H C   1 
ATOM   831  O O   . ASN B 2  53  G -15.202 21.547  -27.804 1.00 29.77 ? 60   ASN H O   1 
ATOM   832  C CB  . ASN B 2  53  G -17.093 20.447  -26.138 1.00 33.82 ? 60   ASN H CB  1 
ATOM   833  C CG  . ASN B 2  53  G -17.366 21.931  -26.003 1.00 39.39 ? 60   ASN H CG  1 
ATOM   834  O OD1 . ASN B 2  53  G -18.201 22.488  -26.717 1.00 37.93 ? 60   ASN H OD1 1 
ATOM   835  N ND2 . ASN B 2  53  G -16.665 22.565  -25.068 1.00 45.31 ? 60   ASN H ND2 1 
ATOM   836  N N   . PHE B 2  54  H -16.142 20.774  -29.705 1.00 29.21 ? 60   PHE H N   1 
ATOM   837  C CA  . PHE B 2  54  H -15.274 21.532  -30.595 1.00 31.81 ? 60   PHE H CA  1 
ATOM   838  C C   . PHE B 2  54  H -15.693 22.993  -30.655 1.00 32.92 ? 60   PHE H C   1 
ATOM   839  O O   . PHE B 2  54  H -16.844 23.308  -30.963 1.00 32.23 ? 60   PHE H O   1 
ATOM   840  C CB  . PHE B 2  54  H -15.315 20.942  -32.004 1.00 31.41 ? 60   PHE H CB  1 
ATOM   841  C CG  . PHE B 2  54  H -14.714 19.572  -32.108 1.00 32.41 ? 60   PHE H CG  1 
ATOM   842  C CD1 . PHE B 2  54  H -13.364 19.367  -31.834 1.00 33.44 ? 60   PHE H CD1 1 
ATOM   843  C CD2 . PHE B 2  54  H -15.492 18.485  -32.492 1.00 32.66 ? 60   PHE H CD2 1 
ATOM   844  C CE1 . PHE B 2  54  H -12.798 18.098  -31.943 1.00 33.71 ? 60   PHE H CE1 1 
ATOM   845  C CE2 . PHE B 2  54  H -14.935 17.211  -32.604 1.00 31.01 ? 60   PHE H CE2 1 
ATOM   846  C CZ  . PHE B 2  54  H -13.586 17.019  -32.330 1.00 33.72 ? 60   PHE H CZ  1 
ATOM   847  N N   . THR B 2  55  I -14.750 23.881  -30.361 1.00 33.70 ? 60   THR H N   1 
ATOM   848  C CA  . THR B 2  55  I -15.009 25.313  -30.385 1.00 34.77 ? 60   THR H CA  1 
ATOM   849  C C   . THR B 2  55  I -14.296 25.929  -31.580 1.00 34.46 ? 60   THR H C   1 
ATOM   850  O O   . THR B 2  55  I -13.654 25.228  -32.360 1.00 33.78 ? 60   THR H O   1 
ATOM   851  C CB  . THR B 2  55  I -14.494 25.995  -29.107 1.00 35.55 ? 60   THR H CB  1 
ATOM   852  O OG1 . THR B 2  55  I -13.082 25.775  -28.989 1.00 37.02 ? 60   THR H OG1 1 
ATOM   853  C CG2 . THR B 2  55  I -15.200 25.434  -27.882 1.00 36.75 ? 60   THR H CG2 1 
ATOM   854  N N   . GLU B 2  56  ? -14.403 27.246  -31.707 1.00 36.02 ? 61   GLU H N   1 
ATOM   855  C CA  . GLU B 2  56  ? -13.777 27.968  -32.807 1.00 38.12 ? 61   GLU H CA  1 
ATOM   856  C C   . GLU B 2  56  ? -12.299 27.636  -32.953 1.00 38.16 ? 61   GLU H C   1 
ATOM   857  O O   . GLU B 2  56  ? -11.814 27.396  -34.054 1.00 38.53 ? 61   GLU H O   1 
ATOM   858  C CB  . GLU B 2  56  ? -13.908 29.479  -32.599 1.00 39.35 ? 61   GLU H CB  1 
ATOM   859  C CG  . GLU B 2  56  ? -15.298 29.962  -32.258 1.00 41.71 ? 61   GLU H CG  1 
ATOM   860  C CD  . GLU B 2  56  ? -15.709 29.624  -30.841 1.00 42.25 ? 61   GLU H CD  1 
ATOM   861  O OE1 . GLU B 2  56  ? -14.965 29.981  -29.904 1.00 44.60 ? 61   GLU H OE1 1 
ATOM   862  O OE2 . GLU B 2  56  ? -16.779 29.008  -30.663 1.00 43.53 ? 61   GLU H OE2 1 
ATOM   863  N N   . ASN B 2  57  ? -11.590 27.624  -31.830 1.00 39.16 ? 62   ASN H N   1 
ATOM   864  C CA  . ASN B 2  57  ? -10.155 27.364  -31.822 1.00 40.59 ? 62   ASN H CA  1 
ATOM   865  C C   . ASN B 2  57  ? -9.727  25.943  -32.161 1.00 39.72 ? 62   ASN H C   1 
ATOM   866  O O   . ASN B 2  57  ? -8.541  25.690  -32.368 1.00 39.83 ? 62   ASN H O   1 
ATOM   867  C CB  . ASN B 2  57  ? -9.573  27.754  -30.462 1.00 42.89 ? 62   ASN H CB  1 
ATOM   868  C CG  . ASN B 2  57  ? -9.810  29.212  -30.128 1.00 44.52 ? 62   ASN H CG  1 
ATOM   869  O OD1 . ASN B 2  57  ? -9.343  30.106  -30.833 1.00 46.23 ? 62   ASN H OD1 1 
ATOM   870  N ND2 . ASN B 2  57  ? -10.542 29.460  -29.049 1.00 46.52 ? 62   ASN H ND2 1 
ATOM   871  N N   . ASP B 2  58  ? -10.678 25.019  -32.223 1.00 37.96 ? 63   ASP H N   1 
ATOM   872  C CA  . ASP B 2  58  ? -10.349 23.632  -32.534 1.00 36.61 ? 63   ASP H CA  1 
ATOM   873  C C   . ASP B 2  58  ? -10.685 23.287  -33.972 1.00 35.21 ? 63   ASP H C   1 
ATOM   874  O O   . ASP B 2  58  ? -10.360 22.198  -34.444 1.00 36.53 ? 63   ASP H O   1 
ATOM   875  C CB  . ASP B 2  58  ? -11.128 22.680  -31.626 1.00 36.68 ? 63   ASP H CB  1 
ATOM   876  C CG  . ASP B 2  58  ? -11.074 23.084  -30.175 1.00 37.34 ? 63   ASP H CG  1 
ATOM   877  O OD1 . ASP B 2  58  ? -9.956  23.275  -29.654 1.00 39.84 ? 63   ASP H OD1 1 
ATOM   878  O OD2 . ASP B 2  58  ? -12.152 23.208  -29.557 1.00 36.38 ? 63   ASP H OD2 1 
ATOM   879  N N   . LEU B 2  59  ? -11.319 24.221  -34.673 1.00 33.65 ? 64   LEU H N   1 
ATOM   880  C CA  . LEU B 2  59  ? -11.745 23.966  -36.040 1.00 31.80 ? 64   LEU H CA  1 
ATOM   881  C C   . LEU B 2  59  ? -11.241 24.913  -37.115 1.00 31.37 ? 64   LEU H C   1 
ATOM   882  O O   . LEU B 2  59  ? -10.711 25.991  -36.845 1.00 30.55 ? 64   LEU H O   1 
ATOM   883  C CB  . LEU B 2  59  ? -13.273 23.961  -36.090 1.00 31.30 ? 64   LEU H CB  1 
ATOM   884  C CG  . LEU B 2  59  ? -13.986 23.095  -35.050 1.00 31.37 ? 64   LEU H CG  1 
ATOM   885  C CD1 . LEU B 2  59  ? -15.410 23.575  -34.877 1.00 30.05 ? 64   LEU H CD1 1 
ATOM   886  C CD2 . LEU B 2  59  ? -13.951 21.644  -35.476 1.00 31.37 ? 64   LEU H CD2 1 
ATOM   887  N N   . LEU B 2  60  ? -11.455 24.485  -38.351 1.00 29.08 ? 65   LEU H N   1 
ATOM   888  C CA  . LEU B 2  60  ? -11.081 25.233  -39.534 1.00 28.16 ? 65   LEU H CA  1 
ATOM   889  C C   . LEU B 2  60  ? -11.961 24.701  -40.667 1.00 25.92 ? 65   LEU H C   1 
ATOM   890  O O   . LEU B 2  60  ? -12.421 23.556  -40.619 1.00 23.67 ? 65   LEU H O   1 
ATOM   891  C CB  . LEU B 2  60  ? -9.588  25.022  -39.814 1.00 31.80 ? 65   LEU H CB  1 
ATOM   892  C CG  . LEU B 2  60  ? -9.042  24.685  -41.200 1.00 34.52 ? 65   LEU H CG  1 
ATOM   893  C CD1 . LEU B 2  60  ? -7.521  24.775  -41.157 1.00 36.48 ? 65   LEU H CD1 1 
ATOM   894  C CD2 . LEU B 2  60  ? -9.470  23.289  -41.616 1.00 35.75 ? 65   LEU H CD2 1 
ATOM   895  N N   . VAL B 2  61  ? -12.232 25.532  -41.665 1.00 22.27 ? 66   VAL H N   1 
ATOM   896  C CA  . VAL B 2  61  ? -13.059 25.091  -42.781 1.00 20.72 ? 66   VAL H CA  1 
ATOM   897  C C   . VAL B 2  61  ? -12.373 25.328  -44.110 1.00 20.45 ? 66   VAL H C   1 
ATOM   898  O O   . VAL B 2  61  ? -11.695 26.340  -44.303 1.00 21.80 ? 66   VAL H O   1 
ATOM   899  C CB  . VAL B 2  61  ? -14.436 25.804  -42.812 1.00 21.94 ? 66   VAL H CB  1 
ATOM   900  C CG1 . VAL B 2  61  ? -15.287 25.355  -41.631 1.00 20.36 ? 66   VAL H CG1 1 
ATOM   901  C CG2 . VAL B 2  61  ? -14.248 27.315  -42.794 1.00 21.55 ? 66   VAL H CG2 1 
ATOM   902  N N   A ARG B 2  62  ? -12.540 24.381  -45.028 0.08 18.64 ? 67   ARG H N   1 
ATOM   903  N N   B ARG B 2  62  ? -12.547 24.381  -45.023 0.92 18.09 ? 67   ARG H N   1 
ATOM   904  C CA  A ARG B 2  62  ? -11.954 24.481  -46.360 0.18 17.07 ? 67   ARG H CA  1 
ATOM   905  C CA  B ARG B 2  62  ? -11.966 24.478  -46.357 0.82 16.87 ? 67   ARG H CA  1 
ATOM   906  C C   A ARG B 2  62  ? -13.100 24.603  -47.357 0.27 16.06 ? 67   ARG H C   1 
ATOM   907  C C   B ARG B 2  62  ? -13.117 24.615  -47.343 0.60 15.74 ? 67   ARG H C   1 
ATOM   908  O O   A ARG B 2  62  ? -14.001 23.764  -47.394 0.24 15.66 ? 67   ARG H O   1 
ATOM   909  O O   B ARG B 2  62  ? -14.042 23.799  -47.357 0.68 14.63 ? 67   ARG H O   1 
ATOM   910  C CB  A ARG B 2  62  ? -11.090 23.248  -46.646 0.12 17.07 ? 67   ARG H CB  1 
ATOM   911  C CB  B ARG B 2  62  ? -11.124 23.234  -46.662 0.88 17.91 ? 67   ARG H CB  1 
ATOM   912  C CG  A ARG B 2  62  ? -9.911  23.130  -45.686 0.33 17.07 ? 67   ARG H CG  1 
ATOM   913  C CG  B ARG B 2  62  ? -9.909  23.104  -45.749 0.55 19.46 ? 67   ARG H CG  1 
ATOM   914  C CD  A ARG B 2  62  ? -9.145  21.822  -45.830 0.10 16.99 ? 67   ARG H CD  1 
ATOM   915  C CD  B ARG B 2  62  ? -9.085  21.854  -46.037 0.65 20.70 ? 67   ARG H CD  1 
ATOM   916  N NE  A ARG B 2  62  ? -8.339  21.744  -47.043 0.27 17.19 ? 67   ARG H NE  1 
ATOM   917  N NE  B ARG B 2  62  ? -7.947  21.737  -45.127 0.20 22.39 ? 67   ARG H NE  1 
ATOM   918  C CZ  A ARG B 2  62  ? -7.528  20.729  -47.329 0.39 16.86 ? 67   ARG H CZ  1 
ATOM   919  C CZ  B ARG B 2  62  ? -6.836  22.462  -45.222 0.44 22.84 ? 67   ARG H CZ  1 
ATOM   920  N NH1 A ARG B 2  62  ? -7.420  19.708  -46.489 0.35 17.63 ? 67   ARG H NH1 1 
ATOM   921  N NH1 B ARG B 2  62  ? -6.707  23.353  -46.192 0.51 22.55 ? 67   ARG H NH1 1 
ATOM   922  N NH2 A ARG B 2  62  ? -6.816  20.735  -48.448 0.55 16.75 ? 67   ARG H NH2 1 
ATOM   923  N NH2 B ARG B 2  62  ? -5.856  22.305  -44.340 0.45 23.36 ? 67   ARG H NH2 1 
ATOM   924  N N   . ILE B 2  63  ? -13.056 25.660  -48.161 1.00 15.22 ? 68   ILE H N   1 
ATOM   925  C CA  . ILE B 2  63  ? -14.108 25.948  -49.129 1.00 13.55 ? 68   ILE H CA  1 
ATOM   926  C C   . ILE B 2  63  ? -13.628 25.898  -50.572 1.00 15.73 ? 68   ILE H C   1 
ATOM   927  O O   . ILE B 2  63  ? -12.484 26.236  -50.858 1.00 17.32 ? 68   ILE H O   1 
ATOM   928  C CB  . ILE B 2  63  ? -14.680 27.357  -48.801 1.00 13.45 ? 68   ILE H CB  1 
ATOM   929  C CG1 . ILE B 2  63  ? -14.930 27.433  -47.288 1.00 13.16 ? 68   ILE H CG1 1 
ATOM   930  C CG2 . ILE B 2  63  ? -15.966 27.631  -49.581 1.00 14.42 ? 68   ILE H CG2 1 
ATOM   931  C CD1 . ILE B 2  63  ? -15.280 28.821  -46.763 1.00 16.87 ? 68   ILE H CD1 1 
ATOM   932  N N   . GLY B 2  64  ? -14.510 25.459  -51.470 1.00 15.22 ? 69   GLY H N   1 
ATOM   933  C CA  . GLY B 2  64  ? -14.180 25.385  -52.881 1.00 17.01 ? 69   GLY H CA  1 
ATOM   934  C C   . GLY B 2  64  ? -13.459 24.122  -53.308 1.00 18.67 ? 69   GLY H C   1 
ATOM   935  O O   . GLY B 2  64  ? -12.949 24.053  -54.429 1.00 20.18 ? 69   GLY H O   1 
ATOM   936  N N   . LYS B 2  65  ? -13.447 23.111  -52.442 1.00 19.53 ? 70   LYS H N   1 
ATOM   937  C CA  . LYS B 2  65  ? -12.750 21.865  -52.736 1.00 20.66 ? 70   LYS H CA  1 
ATOM   938  C C   . LYS B 2  65  ? -13.499 20.820  -53.557 1.00 21.51 ? 70   LYS H C   1 
ATOM   939  O O   . LYS B 2  65  ? -14.734 20.787  -53.604 1.00 20.42 ? 70   LYS H O   1 
ATOM   940  C CB  . LYS B 2  65  ? -12.282 21.205  -51.435 1.00 21.45 ? 70   LYS H CB  1 
ATOM   941  C CG  . LYS B 2  65  ? -11.229 21.986  -50.683 1.00 21.86 ? 70   LYS H CG  1 
ATOM   942  C CD  . LYS B 2  65  ? -10.587 21.138  -49.593 1.00 23.56 ? 70   LYS H CD  1 
ATOM   943  C CE  . LYS B 2  65  ? -9.944  19.893  -50.178 1.00 23.34 ? 70   LYS H CE  1 
ATOM   944  N NZ  . LYS B 2  65  ? -8.999  20.219  -51.282 1.00 21.72 ? 70   LYS H NZ  1 
ATOM   945  N N   . HIS B 2  66  ? -12.713 19.963  -54.204 1.00 19.05 ? 71   HIS H N   1 
ATOM   946  C CA  . HIS B 2  66  ? -13.231 18.870  -55.014 1.00 19.22 ? 71   HIS H CA  1 
ATOM   947  C C   . HIS B 2  66  ? -12.539 17.597  -54.529 1.00 19.01 ? 71   HIS H C   1 
ATOM   948  O O   . HIS B 2  66  ? -13.188 16.600  -54.221 1.00 19.28 ? 71   HIS H O   1 
ATOM   949  C CB  . HIS B 2  66  ? -12.921 19.095  -56.496 1.00 19.21 ? 71   HIS H CB  1 
ATOM   950  C CG  . HIS B 2  66  ? -13.417 18.000  -57.388 1.00 22.09 ? 71   HIS H CG  1 
ATOM   951  N ND1 . HIS B 2  66  ? -14.756 17.795  -57.642 1.00 22.40 ? 71   HIS H ND1 1 
ATOM   952  C CD2 . HIS B 2  66  ? -12.752 17.044  -58.081 1.00 22.31 ? 71   HIS H CD2 1 
ATOM   953  C CE1 . HIS B 2  66  ? -14.895 16.760  -58.454 1.00 23.32 ? 71   HIS H CE1 1 
ATOM   954  N NE2 . HIS B 2  66  ? -13.694 16.287  -58.734 1.00 22.61 ? 71   HIS H NE2 1 
ATOM   955  N N   . SER B 2  67  ? -11.213 17.640  -54.456 1.00 19.55 ? 72   SER H N   1 
ATOM   956  C CA  . SER B 2  67  ? -10.451 16.488  -53.995 1.00 20.20 ? 72   SER H CA  1 
ATOM   957  C C   . SER B 2  67  ? -10.541 16.379  -52.478 1.00 22.25 ? 72   SER H C   1 
ATOM   958  O O   . SER B 2  67  ? -10.541 17.387  -51.773 1.00 23.59 ? 72   SER H O   1 
ATOM   959  C CB  . SER B 2  67  ? -8.987  16.609  -54.411 1.00 20.41 ? 72   SER H CB  1 
ATOM   960  O OG  . SER B 2  67  ? -8.241  15.530  -53.879 1.00 21.48 ? 72   SER H OG  1 
ATOM   961  N N   A ARG B 2  68  ? -10.613 15.145  -51.991 0.16 22.41 ? 73   ARG H N   1 
ATOM   962  N N   B ARG B 2  68  ? -10.616 15.150  -51.977 0.84 22.01 ? 73   ARG H N   1 
ATOM   963  C CA  A ARG B 2  68  ? -10.722 14.868  -50.564 0.10 22.88 ? 73   ARG H CA  1 
ATOM   964  C CA  B ARG B 2  68  ? -10.714 14.920  -50.543 0.71 22.53 ? 73   ARG H CA  1 
ATOM   965  C C   A ARG B 2  68  ? -9.385  15.066  -49.854 0.10 23.63 ? 73   ARG H C   1 
ATOM   966  C C   B ARG B 2  68  ? -9.373  15.127  -49.858 0.79 23.19 ? 73   ARG H C   1 
ATOM   967  O O   A ARG B 2  68  ? -9.344  15.466  -48.690 0.11 23.44 ? 73   ARG H O   1 
ATOM   968  O O   B ARG B 2  68  ? -9.320  15.581  -48.716 0.51 22.98 ? 73   ARG H O   1 
ATOM   969  C CB  A ARG B 2  68  ? -11.209 13.425  -50.370 0.44 22.34 ? 73   ARG H CB  1 
ATOM   970  C CB  B ARG B 2  68  ? -11.203 13.492  -50.263 0.43 22.24 ? 73   ARG H CB  1 
ATOM   971  C CG  A ARG B 2  68  ? -11.844 13.110  -49.020 0.10 22.34 ? 73   ARG H CG  1 
ATOM   972  C CG  B ARG B 2  68  ? -11.314 13.147  -48.777 0.53 22.02 ? 73   ARG H CG  1 
ATOM   973  C CD  A ARG B 2  68  ? -10.854 13.185  -47.873 0.38 22.11 ? 73   ARG H CD  1 
ATOM   974  C CD  B ARG B 2  68  ? -11.798 11.712  -48.566 0.62 22.64 ? 73   ARG H CD  1 
ATOM   975  N NE  A ARG B 2  68  ? -11.378 12.544  -46.671 0.26 22.16 ? 73   ARG H NE  1 
ATOM   976  N NE  B ARG B 2  68  ? -10.812 10.720  -48.990 0.62 22.85 ? 73   ARG H NE  1 
ATOM   977  C CZ  A ARG B 2  68  ? -10.742 12.508  -45.506 0.50 22.28 ? 73   ARG H CZ  1 
ATOM   978  C CZ  B ARG B 2  68  ? -9.740  10.370  -48.284 0.50 24.05 ? 73   ARG H CZ  1 
ATOM   979  N NH1 A ARG B 2  68  ? -9.554  13.081  -45.378 0.33 22.59 ? 73   ARG H NH1 1 
ATOM   980  N NH1 B ARG B 2  68  ? -9.502  10.926  -47.106 0.67 24.52 ? 73   ARG H NH1 1 
ATOM   981  N NH2 A ARG B 2  68  ? -11.294 11.896  -44.467 0.25 22.49 ? 73   ARG H NH2 1 
ATOM   982  N NH2 B ARG B 2  68  ? -8.901  9.462   -48.760 0.75 25.02 ? 73   ARG H NH2 1 
ATOM   983  N N   . THR B 2  69  ? -8.293  14.799  -50.564 1.00 23.90 ? 74   THR H N   1 
ATOM   984  C CA  . THR B 2  69  ? -6.956  14.917  -49.995 1.00 27.38 ? 74   THR H CA  1 
ATOM   985  C C   . THR B 2  69  ? -5.989  15.929  -50.598 1.00 27.61 ? 74   THR H C   1 
ATOM   986  O O   . THR B 2  69  ? -5.100  16.421  -49.902 1.00 30.29 ? 74   THR H O   1 
ATOM   987  C CB  . THR B 2  69  ? -6.247  13.554  -50.035 1.00 28.10 ? 74   THR H CB  1 
ATOM   988  O OG1 . THR B 2  69  ? -6.135  13.122  -51.397 1.00 28.56 ? 74   THR H OG1 1 
ATOM   989  C CG2 . THR B 2  69  ? -7.032  12.518  -49.244 1.00 30.63 ? 74   THR H CG2 1 
ATOM   990  N N   A ARG B 2  70  ? -6.163  16.241  -51.878 0.20 28.17 ? 75   ARG H N   1 
ATOM   991  N N   B ARG B 2  70  ? -6.146  16.229  -51.883 0.80 28.25 ? 75   ARG H N   1 
ATOM   992  C CA  A ARG B 2  70  ? -5.274  17.174  -52.565 0.27 28.15 ? 75   ARG H CA  1 
ATOM   993  C CA  B ARG B 2  70  ? -5.253  17.174  -52.545 0.73 28.26 ? 75   ARG H CA  1 
ATOM   994  C C   A ARG B 2  70  ? -5.630  18.646  -52.369 0.27 28.06 ? 75   ARG H C   1 
ATOM   995  C C   B ARG B 2  70  ? -5.628  18.638  -52.352 0.39 28.08 ? 75   ARG H C   1 
ATOM   996  O O   A ARG B 2  70  ? -6.778  19.047  -52.557 0.24 27.97 ? 75   ARG H O   1 
ATOM   997  O O   B ARG B 2  70  ? -6.784  19.025  -52.518 0.76 27.63 ? 75   ARG H O   1 
ATOM   998  C CB  A ARG B 2  70  ? -5.249  16.849  -54.060 0.50 28.36 ? 75   ARG H CB  1 
ATOM   999  C CB  B ARG B 2  70  ? -5.166  16.864  -54.043 0.50 28.90 ? 75   ARG H CB  1 
ATOM   1000 C CG  A ARG B 2  70  ? -4.134  17.533  -54.827 0.33 28.99 ? 75   ARG H CG  1 
ATOM   1001 C CG  B ARG B 2  70  ? -4.372  15.602  -54.371 0.25 29.75 ? 75   ARG H CG  1 
ATOM   1002 C CD  A ARG B 2  70  ? -4.017  16.982  -56.240 0.53 29.34 ? 75   ARG H CD  1 
ATOM   1003 C CD  B ARG B 2  70  ? -3.345  15.875  -55.463 0.31 30.39 ? 75   ARG H CD  1 
ATOM   1004 N NE  A ARG B 2  70  ? -5.089  17.442  -57.120 0.50 29.93 ? 75   ARG H NE  1 
ATOM   1005 N NE  B ARG B 2  70  ? -2.501  14.718  -55.762 0.50 31.05 ? 75   ARG H NE  1 
ATOM   1006 C CZ  A ARG B 2  70  ? -5.275  18.712  -57.468 0.30 29.75 ? 75   ARG H CZ  1 
ATOM   1007 C CZ  B ARG B 2  70  ? -1.745  14.084  -54.871 0.41 31.00 ? 75   ARG H CZ  1 
ATOM   1008 N NH1 A ARG B 2  70  ? -4.463  19.654  -57.009 0.36 29.97 ? 75   ARG H NH1 1 
ATOM   1009 N NH1 B ARG B 2  70  ? -1.723  14.486  -53.607 0.64 31.35 ? 75   ARG H NH1 1 
ATOM   1010 N NH2 A ARG B 2  70  ? -6.263  19.040  -58.288 0.36 29.77 ? 75   ARG H NH2 1 
ATOM   1011 N NH2 B ARG B 2  70  ? -0.999  13.052  -55.246 0.64 31.15 ? 75   ARG H NH2 1 
ATOM   1012 N N   . TYR B 2  71  ? -4.635  19.445  -51.990 1.00 28.50 ? 76   TYR H N   1 
ATOM   1013 C CA  . TYR B 2  71  ? -4.832  20.875  -51.790 1.00 26.69 ? 76   TYR H CA  1 
ATOM   1014 C C   . TYR B 2  71  ? -4.966  21.445  -53.190 1.00 26.33 ? 76   TYR H C   1 
ATOM   1015 O O   . TYR B 2  71  ? -4.171  21.128  -54.074 1.00 26.63 ? 76   TYR H O   1 
ATOM   1016 C CB  . TYR B 2  71  ? -3.623  21.509  -51.109 1.00 25.50 ? 76   TYR H CB  1 
ATOM   1017 C CG  . TYR B 2  71  ? -3.708  23.021  -51.032 1.00 24.24 ? 76   TYR H CG  1 
ATOM   1018 C CD1 . TYR B 2  71  ? -4.488  23.647  -50.062 1.00 25.07 ? 76   TYR H CD1 1 
ATOM   1019 C CD2 . TYR B 2  71  ? -3.024  23.823  -51.943 1.00 24.91 ? 76   TYR H CD2 1 
ATOM   1020 C CE1 . TYR B 2  71  ? -4.582  25.039  -49.997 1.00 24.10 ? 76   TYR H CE1 1 
ATOM   1021 C CE2 . TYR B 2  71  ? -3.115  25.218  -51.888 1.00 24.52 ? 76   TYR H CE2 1 
ATOM   1022 C CZ  . TYR B 2  71  ? -3.893  25.815  -50.911 1.00 23.86 ? 76   TYR H CZ  1 
ATOM   1023 O OH  . TYR B 2  71  ? -3.971  27.187  -50.835 1.00 23.02 ? 76   TYR H OH  1 
ATOM   1024 N N   . GLU B 2  72  ? -5.964  22.296  -53.391 1.00 24.80 ? 77   GLU H N   1 
ATOM   1025 C CA  . GLU B 2  72  ? -6.216  22.870  -54.701 1.00 21.61 ? 77   GLU H CA  1 
ATOM   1026 C C   . GLU B 2  72  ? -5.867  24.367  -54.760 1.00 22.28 ? 77   GLU H C   1 
ATOM   1027 O O   . GLU B 2  72  ? -6.672  25.229  -54.413 1.00 22.45 ? 77   GLU H O   1 
ATOM   1028 C CB  . GLU B 2  72  ? -7.679  22.561  -55.054 1.00 24.30 ? 77   GLU H CB  1 
ATOM   1029 C CG  . GLU B 2  72  ? -7.901  21.031  -55.028 1.00 22.91 ? 77   GLU H CG  1 
ATOM   1030 C CD  . GLU B 2  72  ? -9.346  20.576  -54.908 1.00 25.55 ? 77   GLU H CD  1 
ATOM   1031 O OE1 . GLU B 2  72  ? -10.019 20.931  -53.916 1.00 23.43 ? 77   GLU H OE1 1 
ATOM   1032 O OE2 . GLU B 2  72  ? -9.804  19.834  -55.805 1.00 25.54 ? 77   GLU H OE2 1 
ATOM   1033 N N   A ARG B 2  73  A -4.657  24.646  -55.236 0.11 20.46 ? 77   ARG H N   1 
ATOM   1034 N N   B ARG B 2  73  A -4.641  24.646  -55.195 0.82 22.07 ? 77   ARG H N   1 
ATOM   1035 C CA  A ARG B 2  73  A -4.110  25.998  -55.355 0.20 19.01 ? 77   ARG H CA  1 
ATOM   1036 C CA  B ARG B 2  73  A -4.119  26.009  -55.287 0.77 21.53 ? 77   ARG H CA  1 
ATOM   1037 C C   A ARG B 2  73  A -5.002  27.065  -55.998 0.10 19.35 ? 77   ARG H C   1 
ATOM   1038 C C   B ARG B 2  73  A -4.931  26.971  -56.149 0.73 21.44 ? 77   ARG H C   1 
ATOM   1039 O O   A ARG B 2  73  A -5.535  26.878  -57.092 0.23 18.89 ? 77   ARG H O   1 
ATOM   1040 O O   B ARG B 2  73  A -5.346  26.644  -57.262 0.70 20.51 ? 77   ARG H O   1 
ATOM   1041 C CB  A ARG B 2  73  A -2.779  25.927  -56.110 0.58 17.05 ? 77   ARG H CB  1 
ATOM   1042 C CB  B ARG B 2  73  A -2.662  25.972  -55.768 0.42 22.11 ? 77   ARG H CB  1 
ATOM   1043 C CG  A ARG B 2  73  A -1.956  27.209  -56.100 0.10 14.29 ? 77   ARG H CG  1 
ATOM   1044 C CG  B ARG B 2  73  A -2.011  27.342  -55.929 0.90 22.45 ? 77   ARG H CG  1 
ATOM   1045 C CD  A ARG B 2  73  A -0.549  26.913  -56.598 0.54 10.95 ? 77   ARG H CD  1 
ATOM   1046 C CD  B ARG B 2  73  A -0.493  27.255  -55.849 0.13 23.43 ? 77   ARG H CD  1 
ATOM   1047 N NE  A ARG B 2  73  A 0.355   28.058  -56.530 0.29 9.57  ? 77   ARG H NE  1 
ATOM   1048 N NE  B ARG B 2  73  A 0.144   28.508  -56.243 0.63 24.45 ? 77   ARG H NE  1 
ATOM   1049 C CZ  A ARG B 2  73  A 0.330   29.095  -57.360 0.42 9.24  ? 77   ARG H CZ  1 
ATOM   1050 C CZ  B ARG B 2  73  A 1.322   28.932  -55.794 0.45 24.36 ? 77   ARG H CZ  1 
ATOM   1051 N NH1 A ARG B 2  73  A -0.561  29.151  -58.340 0.28 7.99  ? 77   ARG H NH1 1 
ATOM   1052 N NH1 B ARG B 2  73  A 2.014   28.209  -54.919 0.72 24.69 ? 77   ARG H NH1 1 
ATOM   1053 N NH2 A ARG B 2  73  A 1.211   30.076  -57.218 0.26 7.54  ? 77   ARG H NH2 1 
ATOM   1054 N NH2 B ARG B 2  73  A 1.811   30.085  -56.227 0.57 24.42 ? 77   ARG H NH2 1 
ATOM   1055 N N   A ASN B 2  74  ? -5.135  28.190  -55.299 0.10 19.86 ? 78   ASN H N   1 
ATOM   1056 N N   B ASN B 2  74  ? -5.136  28.172  -55.616 0.83 21.34 ? 78   ASN H N   1 
ATOM   1057 C CA  A ASN B 2  74  ? -5.923  29.341  -55.742 0.35 20.71 ? 78   ASN H CA  1 
ATOM   1058 C CA  B ASN B 2  74  ? -5.898  29.211  -56.292 0.45 22.08 ? 78   ASN H CA  1 
ATOM   1059 C C   A ASN B 2  74  ? -7.406  29.049  -55.967 0.37 20.70 ? 78   ASN H C   1 
ATOM   1060 C C   B ASN B 2  74  ? -7.333  28.769  -56.547 0.48 21.41 ? 78   ASN H C   1 
ATOM   1061 O O   A ASN B 2  74  ? -8.172  29.945  -56.309 0.30 20.57 ? 78   ASN H O   1 
ATOM   1062 O O   B ASN B 2  74  ? -8.014  29.294  -57.432 0.67 21.09 ? 78   ASN H O   1 
ATOM   1063 C CB  A ASN B 2  74  ? -5.317  29.935  -57.017 0.44 21.52 ? 78   ASN H CB  1 
ATOM   1064 C CB  B ASN B 2  74  ? -5.214  29.608  -57.604 0.46 24.03 ? 78   ASN H CB  1 
ATOM   1065 C CG  A ASN B 2  74  ? -5.793  31.350  -57.283 0.31 22.58 ? 78   ASN H CG  1 
ATOM   1066 C CG  B ASN B 2  74  ? -3.964  30.449  -57.378 0.69 25.75 ? 78   ASN H CG  1 
ATOM   1067 O OD1 A ASN B 2  74  ? -5.619  32.241  -56.451 0.33 23.45 ? 78   ASN H OD1 1 
ATOM   1068 O OD1 B ASN B 2  74  ? -3.209  30.721  -58.311 0.17 26.65 ? 78   ASN H OD1 1 
ATOM   1069 N ND2 A ASN B 2  74  ? -6.393  31.565  -58.447 0.14 22.74 ? 78   ASN H ND2 1 
ATOM   1070 N ND2 B ASN B 2  74  ? -3.750  30.872  -56.139 0.86 28.06 ? 78   ASN H ND2 1 
ATOM   1071 N N   . ILE B 2  75  ? -7.794  27.793  -55.773 1.00 20.69 ? 79   ILE H N   1 
ATOM   1072 C CA  . ILE B 2  75  ? -9.173  27.341  -55.927 1.00 21.60 ? 79   ILE H CA  1 
ATOM   1073 C C   . ILE B 2  75  ? -9.811  27.192  -54.551 1.00 22.75 ? 79   ILE H C   1 
ATOM   1074 O O   . ILE B 2  75  ? -10.841 27.806  -54.260 1.00 22.67 ? 79   ILE H O   1 
ATOM   1075 C CB  . ILE B 2  75  ? -9.261  25.990  -56.662 1.00 23.73 ? 79   ILE H CB  1 
ATOM   1076 C CG1 . ILE B 2  75  ? -8.858  26.169  -58.127 1.00 25.69 ? 79   ILE H CG1 1 
ATOM   1077 C CG2 . ILE B 2  75  ? -10.688 25.434  -56.572 1.00 24.94 ? 79   ILE H CG2 1 
ATOM   1078 C CD1 . ILE B 2  75  ? -8.963  24.902  -58.946 1.00 26.92 ? 79   ILE H CD1 1 
ATOM   1079 N N   . GLU B 2  76  ? -9.200  26.389  -53.690 1.00 21.68 ? 80   GLU H N   1 
ATOM   1080 C CA  . GLU B 2  76  ? -9.770  26.215  -52.365 1.00 21.98 ? 80   GLU H CA  1 
ATOM   1081 C C   . GLU B 2  76  ? -9.328  27.338  -51.442 1.00 22.82 ? 80   GLU H C   1 
ATOM   1082 O O   . GLU B 2  76  ? -8.261  27.939  -51.624 1.00 23.16 ? 80   GLU H O   1 
ATOM   1083 C CB  . GLU B 2  76  ? -9.381  24.862  -51.770 1.00 24.07 ? 80   GLU H CB  1 
ATOM   1084 C CG  . GLU B 2  76  ? -8.035  24.813  -51.088 1.00 25.70 ? 80   GLU H CG  1 
ATOM   1085 C CD  . GLU B 2  76  ? -7.808  23.484  -50.386 1.00 25.86 ? 80   GLU H CD  1 
ATOM   1086 O OE1 . GLU B 2  76  ? -7.687  22.457  -51.086 1.00 23.70 ? 80   GLU H OE1 1 
ATOM   1087 O OE2 . GLU B 2  76  ? -7.760  23.464  -49.139 1.00 27.04 ? 80   GLU H OE2 1 
ATOM   1088 N N   . LYS B 2  77  ? -10.175 27.634  -50.466 1.00 20.85 ? 81   LYS H N   1 
ATOM   1089 C CA  . LYS B 2  77  ? -9.890  28.674  -49.497 1.00 20.50 ? 81   LYS H CA  1 
ATOM   1090 C C   . LYS B 2  77  ? -10.067 28.121  -48.096 1.00 21.55 ? 81   LYS H C   1 
ATOM   1091 O O   . LYS B 2  77  ? -11.021 27.388  -47.811 1.00 22.14 ? 81   LYS H O   1 
ATOM   1092 C CB  . LYS B 2  77  ? -10.820 29.869  -49.704 1.00 21.52 ? 81   LYS H CB  1 
ATOM   1093 C CG  . LYS B 2  77  ? -10.662 30.543  -51.053 1.00 22.54 ? 81   LYS H CG  1 
ATOM   1094 C CD  . LYS B 2  77  ? -9.272  31.154  -51.204 1.00 24.39 ? 81   LYS H CD  1 
ATOM   1095 C CE  . LYS B 2  77  ? -9.116  31.830  -52.556 1.00 27.10 ? 81   LYS H CE  1 
ATOM   1096 N NZ  . LYS B 2  77  ? -7.760  32.434  -52.716 1.00 27.24 ? 81   LYS H NZ  1 
ATOM   1097 N N   A ILE B 2  78  ? -9.113  28.427  -47.226 0.10 20.58 ? 82   ILE H N   1 
ATOM   1098 N N   B ILE B 2  78  ? -9.163  28.514  -47.211 0.90 22.36 ? 82   ILE H N   1 
ATOM   1099 C CA  A ILE B 2  78  ? -9.161  27.948  -45.853 0.10 19.87 ? 82   ILE H CA  1 
ATOM   1100 C CA  B ILE B 2  78  ? -9.216  28.082  -45.826 0.90 23.51 ? 82   ILE H CA  1 
ATOM   1101 C C   A ILE B 2  78  ? -9.469  29.106  -44.919 0.12 19.05 ? 82   ILE H C   1 
ATOM   1102 C C   B ILE B 2  78  ? -9.692  29.258  -44.991 0.74 23.83 ? 82   ILE H C   1 
ATOM   1103 O O   A ILE B 2  78  ? -9.034  30.234  -45.150 0.12 18.97 ? 82   ILE H O   1 
ATOM   1104 O O   B ILE B 2  78  ? -9.134  30.350  -45.069 0.53 24.16 ? 82   ILE H O   1 
ATOM   1105 C CB  A ILE B 2  78  ? -7.823  27.296  -45.448 0.48 20.38 ? 82   ILE H CB  1 
ATOM   1106 C CB  B ILE B 2  78  ? -7.831  27.632  -45.329 0.10 24.23 ? 82   ILE H CB  1 
ATOM   1107 C CG1 A ILE B 2  78  ? -7.530  26.111  -46.372 0.21 20.57 ? 82   ILE H CG1 1 
ATOM   1108 C CG1 B ILE B 2  78  ? -7.171  26.744  -46.385 0.21 24.83 ? 82   ILE H CG1 1 
ATOM   1109 C CG2 A ILE B 2  78  ? -7.883  26.833  -43.999 0.10 20.29 ? 82   ILE H CG2 1 
ATOM   1110 C CG2 B ILE B 2  78  ? -7.968  26.878  -44.017 0.61 24.93 ? 82   ILE H CG2 1 
ATOM   1111 C CD1 A ILE B 2  78  ? -6.205  25.431  -46.107 0.33 20.78 ? 82   ILE H CD1 1 
ATOM   1112 C CD1 B ILE B 2  78  ? -8.074  25.651  -46.920 0.47 25.83 ? 82   ILE H CD1 1 
ATOM   1113 N N   A SER B 2  79  ? -10.224 28.825  -43.863 0.33 17.86 ? 83   SER H N   1 
ATOM   1114 N N   B SER B 2  79  ? -10.734 29.035  -44.200 0.67 23.90 ? 83   SER H N   1 
ATOM   1115 C CA  A SER B 2  79  ? -10.601 29.860  -42.913 0.54 17.03 ? 83   SER H CA  1 
ATOM   1116 C CA  B SER B 2  79  ? -11.281 30.090  -43.362 0.35 23.61 ? 83   SER H CA  1 
ATOM   1117 C C   A SER B 2  79  ? -10.871 29.323  -41.518 0.56 16.93 ? 83   SER H C   1 
ATOM   1118 C C   B SER B 2  79  ? -11.349 29.664  -41.907 0.44 23.82 ? 83   SER H C   1 
ATOM   1119 O O   A SER B 2  79  ? -11.246 28.163  -41.348 0.55 15.96 ? 83   SER H O   1 
ATOM   1120 O O   B SER B 2  79  ? -11.891 28.607  -41.585 0.26 23.56 ? 83   SER H O   1 
ATOM   1121 C CB  A SER B 2  79  ? -11.844 30.593  -43.420 0.28 17.08 ? 83   SER H CB  1 
ATOM   1122 C CB  B SER B 2  79  ? -12.688 30.470  -43.836 0.68 23.53 ? 83   SER H CB  1 
ATOM   1123 O OG  A SER B 2  79  ? -12.420 31.389  -42.402 0.35 17.25 ? 83   SER H OG  1 
ATOM   1124 O OG  B SER B 2  79  ? -12.679 30.918  -45.180 0.42 22.53 ? 83   SER H OG  1 
ATOM   1125 N N   A MET B 2  80  ? -10.668 30.183  -40.523 0.43 17.32 ? 84   MET H N   1 
ATOM   1126 N N   B MET B 2  80  ? -10.788 30.483  -41.026 0.55 23.61 ? 84   MET H N   1 
ATOM   1127 C CA  A MET B 2  80  ? -10.911 29.842  -39.128 0.41 17.90 ? 84   MET H CA  1 
ATOM   1128 C CA  B MET B 2  80  ? -10.840 30.185  -39.606 0.59 23.34 ? 84   MET H CA  1 
ATOM   1129 C C   A MET B 2  80  ? -12.303 30.367  -38.791 0.30 18.14 ? 84   MET H C   1 
ATOM   1130 C C   B MET B 2  80  ? -12.238 30.596  -39.173 0.70 22.20 ? 84   MET H C   1 
ATOM   1131 O O   A MET B 2  80  ? -12.884 31.126  -39.567 0.11 18.00 ? 84   MET H O   1 
ATOM   1132 O O   B MET B 2  80  ? -12.969 31.209  -39.950 0.83 21.07 ? 84   MET H O   1 
ATOM   1133 C CB  A MET B 2  80  ? -9.871  30.513  -38.225 0.36 18.58 ? 84   MET H CB  1 
ATOM   1134 C CB  B MET B 2  80  ? -9.792  30.995  -38.840 0.45 25.31 ? 84   MET H CB  1 
ATOM   1135 C CG  A MET B 2  80  ? -8.443  30.051  -38.469 0.28 19.42 ? 84   MET H CG  1 
ATOM   1136 C CG  B MET B 2  80  ? -8.366  30.537  -39.086 0.59 27.92 ? 84   MET H CG  1 
ATOM   1137 S SD  A MET B 2  80  ? -7.233  30.938  -37.467 0.18 20.86 ? 84   MET H SD  1 
ATOM   1138 S SD  B MET B 2  80  ? -8.140  28.812  -38.621 0.50 30.10 ? 84   MET H SD  1 
ATOM   1139 C CE  A MET B 2  80  ? -6.853  32.300  -38.546 0.44 21.72 ? 84   MET H CE  1 
ATOM   1140 C CE  B MET B 2  80  ? -7.916  28.967  -36.855 0.56 31.94 ? 84   MET H CE  1 
ATOM   1141 N N   A LEU B 2  81  ? -12.840 29.968  -37.643 0.25 18.68 ? 85   LEU H N   1 
ATOM   1142 N N   B LEU B 2  81  ? -12.614 30.254  -37.947 0.67 21.88 ? 85   LEU H N   1 
ATOM   1143 C CA  A LEU B 2  81  ? -14.168 30.419  -37.241 0.16 19.49 ? 85   LEU H CA  1 
ATOM   1144 C CA  B LEU B 2  81  ? -13.935 30.600  -37.442 0.84 21.72 ? 85   LEU H CA  1 
ATOM   1145 C C   A LEU B 2  81  ? -14.106 31.452  -36.126 0.11 20.09 ? 85   LEU H C   1 
ATOM   1146 C C   B LEU B 2  81  ? -13.841 31.634  -36.330 0.89 21.69 ? 85   LEU H C   1 
ATOM   1147 O O   A LEU B 2  81  ? -13.467 31.230  -35.097 0.29 20.09 ? 85   LEU H O   1 
ATOM   1148 O O   B LEU B 2  81  ? -12.944 31.573  -35.489 0.61 21.34 ? 85   LEU H O   1 
ATOM   1149 C CB  A LEU B 2  81  ? -15.025 29.237  -36.773 0.37 19.58 ? 85   LEU H CB  1 
ATOM   1150 C CB  B LEU B 2  81  ? -14.641 29.346  -36.923 0.63 22.43 ? 85   LEU H CB  1 
ATOM   1151 C CG  A LEU B 2  81  ? -15.352 28.120  -37.768 0.46 19.64 ? 85   LEU H CG  1 
ATOM   1152 C CG  B LEU B 2  81  ? -14.928 28.274  -37.979 0.34 22.66 ? 85   LEU H CG  1 
ATOM   1153 C CD1 A LEU B 2  81  ? -15.993 28.709  -39.017 0.15 19.39 ? 85   LEU H CD1 1 
ATOM   1154 C CD1 B LEU B 2  81  ? -15.434 27.016  -37.302 0.63 23.32 ? 85   LEU H CD1 1 
ATOM   1155 C CD2 A LEU B 2  81  ? -14.085 27.364  -38.121 0.50 19.42 ? 85   LEU H CD2 1 
ATOM   1156 C CD2 B LEU B 2  81  ? -15.948 28.795  -38.986 0.50 22.73 ? 85   LEU H CD2 1 
ATOM   1157 N N   . GLU B 2  82  ? -14.770 32.585  -36.336 1.00 20.78 ? 86   GLU H N   1 
ATOM   1158 C CA  . GLU B 2  82  ? -14.802 33.632  -35.325 1.00 21.84 ? 86   GLU H CA  1 
ATOM   1159 C C   . GLU B 2  82  ? -15.563 33.070  -34.136 1.00 22.66 ? 86   GLU H C   1 
ATOM   1160 O O   . GLU B 2  82  ? -15.128 33.192  -32.990 1.00 23.69 ? 86   GLU H O   1 
ATOM   1161 C CB  . GLU B 2  82  ? -15.528 34.874  -35.844 1.00 23.46 ? 86   GLU H CB  1 
ATOM   1162 C CG  . GLU B 2  82  ? -15.652 35.987  -34.806 1.00 26.37 ? 86   GLU H CG  1 
ATOM   1163 C CD  . GLU B 2  82  ? -16.424 37.193  -35.319 1.00 27.97 ? 86   GLU H CD  1 
ATOM   1164 O OE1 . GLU B 2  82  ? -16.035 37.743  -36.370 1.00 31.26 ? 86   GLU H OE1 1 
ATOM   1165 O OE2 . GLU B 2  82  ? -17.418 37.592  -34.669 1.00 28.47 ? 86   GLU H OE2 1 
ATOM   1166 N N   . LYS B 2  83  ? -16.703 32.445  -34.417 1.00 21.03 ? 87   LYS H N   1 
ATOM   1167 C CA  . LYS B 2  83  ? -17.523 31.864  -33.365 1.00 21.36 ? 87   LYS H CA  1 
ATOM   1168 C C   . LYS B 2  83  ? -18.470 30.803  -33.917 1.00 20.17 ? 87   LYS H C   1 
ATOM   1169 O O   . LYS B 2  83  ? -18.820 30.819  -35.099 1.00 19.16 ? 87   LYS H O   1 
ATOM   1170 C CB  . LYS B 2  83  ? -18.335 32.958  -32.676 1.00 24.69 ? 87   LYS H CB  1 
ATOM   1171 C CG  . LYS B 2  83  ? -18.849 32.580  -31.293 1.00 27.47 ? 87   LYS H CG  1 
ATOM   1172 C CD  . LYS B 2  83  ? -17.693 32.373  -30.320 1.00 29.66 ? 87   LYS H CD  1 
ATOM   1173 N N   A ILE B 2  84  ? -18.869 29.869  -33.059 0.15 19.41 ? 88   ILE H N   1 
ATOM   1174 N N   B ILE B 2  84  ? -18.874 29.881  -33.052 0.85 20.29 ? 88   ILE H N   1 
ATOM   1175 C CA  A ILE B 2  84  ? -19.791 28.812  -33.458 0.19 18.49 ? 88   ILE H CA  1 
ATOM   1176 C CA  B ILE B 2  84  ? -19.795 28.820  -33.433 0.81 19.51 ? 88   ILE H CA  1 
ATOM   1177 C C   A ILE B 2  84  ? -21.023 28.892  -32.564 0.45 17.93 ? 88   ILE H C   1 
ATOM   1178 C C   B ILE B 2  84  ? -21.033 28.922  -32.558 0.55 18.66 ? 88   ILE H C   1 
ATOM   1179 O O   A ILE B 2  84  ? -20.917 29.173  -31.370 0.10 17.61 ? 88   ILE H O   1 
ATOM   1180 O O   B ILE B 2  84  ? -20.940 29.250  -31.372 0.90 18.25 ? 88   ILE H O   1 
ATOM   1181 C CB  A ILE B 2  84  ? -19.130 27.407  -33.349 0.50 18.83 ? 88   ILE H CB  1 
ATOM   1182 C CB  B ILE B 2  84  ? -19.153 27.429  -33.251 0.50 20.73 ? 88   ILE H CB  1 
ATOM   1183 C CG1 A ILE B 2  84  ? -18.854 27.043  -31.889 0.47 18.95 ? 88   ILE H CG1 1 
ATOM   1184 C CG1 B ILE B 2  84  ? -17.988 27.271  -34.227 0.53 22.12 ? 88   ILE H CG1 1 
ATOM   1185 C CG2 A ILE B 2  84  ? -17.832 27.389  -34.140 0.10 19.02 ? 88   ILE H CG2 1 
ATOM   1186 C CG2 B ILE B 2  84  ? -20.189 26.339  -33.476 0.40 21.32 ? 88   ILE H CG2 1 
ATOM   1187 C CD1 A ILE B 2  84  ? -20.021 26.363  -31.189 0.37 19.91 ? 88   ILE H CD1 1 
ATOM   1188 C CD1 B ILE B 2  84  ? -17.206 26.003  -34.026 0.49 22.70 ? 88   ILE H CD1 1 
ATOM   1189 N N   . TYR B 2  85  ? -22.192 28.654  -33.148 1.00 16.02 ? 89   TYR H N   1 
ATOM   1190 C CA  . TYR B 2  85  ? -23.449 28.725  -32.412 1.00 17.39 ? 89   TYR H CA  1 
ATOM   1191 C C   . TYR B 2  85  ? -24.288 27.475  -32.621 1.00 16.05 ? 89   TYR H C   1 
ATOM   1192 O O   . TYR B 2  85  ? -24.773 27.222  -33.719 1.00 16.60 ? 89   TYR H O   1 
ATOM   1193 C CB  . TYR B 2  85  ? -24.232 29.955  -32.874 1.00 18.06 ? 89   TYR H CB  1 
ATOM   1194 C CG  . TYR B 2  85  ? -23.445 31.238  -32.712 1.00 21.74 ? 89   TYR H CG  1 
ATOM   1195 C CD1 . TYR B 2  85  ? -23.379 31.883  -31.477 1.00 24.01 ? 89   TYR H CD1 1 
ATOM   1196 C CD2 . TYR B 2  85  ? -22.724 31.779  -33.780 1.00 22.61 ? 89   TYR H CD2 1 
ATOM   1197 C CE1 . TYR B 2  85  ? -22.610 33.035  -31.306 1.00 26.44 ? 89   TYR H CE1 1 
ATOM   1198 C CE2 . TYR B 2  85  ? -21.950 32.932  -33.619 1.00 25.49 ? 89   TYR H CE2 1 
ATOM   1199 C CZ  . TYR B 2  85  ? -21.901 33.550  -32.378 1.00 26.86 ? 89   TYR H CZ  1 
ATOM   1200 O OH  . TYR B 2  85  ? -21.142 34.685  -32.199 1.00 29.75 ? 89   TYR H OH  1 
ATOM   1201 N N   . ILE B 2  86  ? -24.467 26.709  -31.552 1.00 15.79 ? 90   ILE H N   1 
ATOM   1202 C CA  . ILE B 2  86  ? -25.248 25.481  -31.607 1.00 16.50 ? 90   ILE H CA  1 
ATOM   1203 C C   . ILE B 2  86  ? -26.651 25.746  -31.071 1.00 17.32 ? 90   ILE H C   1 
ATOM   1204 O O   . ILE B 2  86  ? -26.826 26.523  -30.127 1.00 17.60 ? 90   ILE H O   1 
ATOM   1205 C CB  . ILE B 2  86  ? -24.564 24.379  -30.767 1.00 18.65 ? 90   ILE H CB  1 
ATOM   1206 C CG1 . ILE B 2  86  ? -23.127 24.179  -31.263 1.00 20.28 ? 90   ILE H CG1 1 
ATOM   1207 C CG2 . ILE B 2  86  ? -25.351 23.074  -30.869 1.00 17.18 ? 90   ILE H CG2 1 
ATOM   1208 C CD1 . ILE B 2  86  ? -22.296 23.251  -30.405 1.00 23.88 ? 90   ILE H CD1 1 
ATOM   1209 N N   . HIS B 2  87  ? -27.657 25.117  -31.669 1.00 17.21 ? 91   HIS H N   1 
ATOM   1210 C CA  . HIS B 2  87  ? -29.021 25.331  -31.207 1.00 16.65 ? 91   HIS H CA  1 
ATOM   1211 C C   . HIS B 2  87  ? -29.083 24.953  -29.730 1.00 18.29 ? 91   HIS H C   1 
ATOM   1212 O O   . HIS B 2  87  ? -28.696 23.848  -29.348 1.00 17.20 ? 91   HIS H O   1 
ATOM   1213 C CB  . HIS B 2  87  ? -30.016 24.491  -32.010 1.00 16.85 ? 91   HIS H CB  1 
ATOM   1214 C CG  . HIS B 2  87  ? -31.434 24.938  -31.843 1.00 17.25 ? 91   HIS H CG  1 
ATOM   1215 N ND1 . HIS B 2  87  ? -32.073 24.935  -30.621 1.00 18.22 ? 91   HIS H ND1 1 
ATOM   1216 C CD2 . HIS B 2  87  ? -32.311 25.473  -32.725 1.00 16.50 ? 91   HIS H CD2 1 
ATOM   1217 C CE1 . HIS B 2  87  ? -33.280 25.453  -30.757 1.00 18.05 ? 91   HIS H CE1 1 
ATOM   1218 N NE2 . HIS B 2  87  ? -33.450 25.789  -32.023 1.00 17.81 ? 91   HIS H NE2 1 
ATOM   1219 N N   . PRO B 2  88  ? -29.569 25.873  -28.878 1.00 19.14 ? 92   PRO H N   1 
ATOM   1220 C CA  . PRO B 2  88  ? -29.664 25.614  -27.437 1.00 21.10 ? 92   PRO H CA  1 
ATOM   1221 C C   . PRO B 2  88  ? -30.512 24.417  -27.026 1.00 20.94 ? 92   PRO H C   1 
ATOM   1222 O O   . PRO B 2  88  ? -30.313 23.855  -25.945 1.00 22.77 ? 92   PRO H O   1 
ATOM   1223 C CB  . PRO B 2  88  ? -30.194 26.938  -26.880 1.00 21.17 ? 92   PRO H CB  1 
ATOM   1224 C CG  . PRO B 2  88  ? -30.986 27.498  -28.007 1.00 23.57 ? 92   PRO H CG  1 
ATOM   1225 C CD  . PRO B 2  88  ? -30.115 27.200  -29.212 1.00 20.04 ? 92   PRO H CD  1 
ATOM   1226 N N   A ARG B 2  89  ? -31.456 24.016  -27.869 0.22 20.74 ? 93   ARG H N   1 
ATOM   1227 N N   B ARG B 2  89  ? -31.455 24.037  -27.886 0.78 20.73 ? 93   ARG H N   1 
ATOM   1228 C CA  A ARG B 2  89  ? -32.287 22.871  -27.529 0.23 20.42 ? 93   ARG H CA  1 
ATOM   1229 C CA  B ARG B 2  89  ? -32.334 22.905  -27.616 0.70 21.27 ? 93   ARG H CA  1 
ATOM   1230 C C   A ARG B 2  89  ? -31.943 21.634  -28.350 0.10 19.81 ? 93   ARG H C   1 
ATOM   1231 C C   B ARG B 2  89  ? -31.976 21.678  -28.450 0.82 20.61 ? 93   ARG H C   1 
ATOM   1232 O O   A ARG B 2  89  ? -32.764 20.731  -28.509 0.28 19.69 ? 93   ARG H O   1 
ATOM   1233 O O   B ARG B 2  89  ? -32.819 20.822  -28.710 0.72 20.47 ? 93   ARG H O   1 
ATOM   1234 C CB  A ARG B 2  89  ? -33.771 23.219  -27.668 0.24 20.87 ? 93   ARG H CB  1 
ATOM   1235 C CB  B ARG B 2  89  ? -33.794 23.296  -27.859 0.76 22.90 ? 93   ARG H CB  1 
ATOM   1236 C CG  A ARG B 2  89  ? -34.231 24.274  -26.666 0.50 21.50 ? 93   ARG H CG  1 
ATOM   1237 C CG  B ARG B 2  89  ? -34.337 24.288  -26.836 0.50 23.97 ? 93   ARG H CG  1 
ATOM   1238 C CD  A ARG B 2  89  ? -35.713 24.155  -26.348 0.40 21.60 ? 93   ARG H CD  1 
ATOM   1239 C CD  B ARG B 2  89  ? -35.761 24.722  -27.157 0.60 25.35 ? 93   ARG H CD  1 
ATOM   1240 N NE  A ARG B 2  89  ? -36.558 24.301  -27.528 0.10 22.07 ? 93   ARG H NE  1 
ATOM   1241 N NE  B ARG B 2  89  ? -36.711 23.614  -27.107 0.29 25.99 ? 93   ARG H NE  1 
ATOM   1242 C CZ  A ARG B 2  89  ? -37.885 24.226  -27.506 0.36 22.26 ? 93   ARG H CZ  1 
ATOM   1243 C CZ  B ARG B 2  89  ? -38.011 23.735  -27.358 0.16 26.42 ? 93   ARG H CZ  1 
ATOM   1244 N NH1 A ARG B 2  89  ? -38.520 24.007  -26.362 0.24 22.48 ? 93   ARG H NH1 1 
ATOM   1245 N NH1 B ARG B 2  89  ? -38.519 24.918  -27.677 0.11 26.69 ? 93   ARG H NH1 1 
ATOM   1246 N NH2 A ARG B 2  89  ? -38.580 24.368  -28.625 0.18 22.41 ? 93   ARG H NH2 1 
ATOM   1247 N NH2 B ARG B 2  89  ? -38.804 22.674  -27.290 0.33 27.00 ? 93   ARG H NH2 1 
ATOM   1248 N N   . TYR B 2  90  ? -30.718 21.601  -28.869 1.00 19.33 ? 94   TYR H N   1 
ATOM   1249 C CA  . TYR B 2  90  ? -30.245 20.455  -29.642 1.00 17.55 ? 94   TYR H CA  1 
ATOM   1250 C C   . TYR B 2  90  ? -30.350 19.305  -28.631 1.00 19.29 ? 94   TYR H C   1 
ATOM   1251 O O   . TYR B 2  90  ? -29.716 19.339  -27.573 1.00 17.67 ? 94   TYR H O   1 
ATOM   1252 C CB  . TYR B 2  90  ? -28.804 20.731  -30.089 1.00 17.61 ? 94   TYR H CB  1 
ATOM   1253 C CG  . TYR B 2  90  ? -27.889 19.542  -30.247 1.00 17.90 ? 94   TYR H CG  1 
ATOM   1254 C CD1 . TYR B 2  90  ? -28.212 18.474  -31.087 1.00 17.65 ? 94   TYR H CD1 1 
ATOM   1255 C CD2 . TYR B 2  90  ? -26.666 19.509  -29.582 1.00 15.87 ? 94   TYR H CD2 1 
ATOM   1256 C CE1 . TYR B 2  90  ? -27.324 17.403  -31.252 1.00 17.35 ? 94   TYR H CE1 1 
ATOM   1257 C CE2 . TYR B 2  90  ? -25.780 18.453  -29.737 1.00 16.02 ? 94   TYR H CE2 1 
ATOM   1258 C CZ  . TYR B 2  90  ? -26.113 17.405  -30.571 1.00 15.23 ? 94   TYR H CZ  1 
ATOM   1259 O OH  . TYR B 2  90  ? -25.218 16.375  -30.705 1.00 16.96 ? 94   TYR H OH  1 
ATOM   1260 N N   . ASN B 2  91  ? -31.173 18.307  -28.947 1.00 17.69 ? 95   ASN H N   1 
ATOM   1261 C CA  . ASN B 2  91  ? -31.426 17.182  -28.033 1.00 17.61 ? 95   ASN H CA  1 
ATOM   1262 C C   . ASN B 2  91  ? -30.462 16.006  -28.176 1.00 18.90 ? 95   ASN H C   1 
ATOM   1263 O O   . ASN B 2  91  ? -30.817 14.965  -28.734 1.00 20.86 ? 95   ASN H O   1 
ATOM   1264 C CB  . ASN B 2  91  ? -32.867 16.691  -28.232 1.00 18.91 ? 95   ASN H CB  1 
ATOM   1265 C CG  . ASN B 2  91  ? -33.363 15.830  -27.078 1.00 20.74 ? 95   ASN H CG  1 
ATOM   1266 O OD1 . ASN B 2  91  ? -32.573 15.296  -26.303 1.00 20.74 ? 95   ASN H OD1 1 
ATOM   1267 N ND2 . ASN B 2  91  ? -34.679 15.685  -26.973 1.00 21.14 ? 95   ASN H ND2 1 
ATOM   1268 N N   . TRP B 2  92  ? -29.252 16.164  -27.648 1.00 18.31 ? 96   TRP H N   1 
ATOM   1269 C CA  . TRP B 2  92  ? -28.240 15.117  -27.734 1.00 19.78 ? 96   TRP H CA  1 
ATOM   1270 C C   . TRP B 2  92  ? -28.537 13.920  -26.839 1.00 22.21 ? 96   TRP H C   1 
ATOM   1271 O O   . TRP B 2  92  ? -27.991 12.837  -27.046 1.00 22.35 ? 96   TRP H O   1 
ATOM   1272 C CB  . TRP B 2  92  ? -26.859 15.676  -27.379 1.00 22.12 ? 96   TRP H CB  1 
ATOM   1273 C CG  . TRP B 2  92  ? -26.811 16.397  -26.066 1.00 23.97 ? 96   TRP H CG  1 
ATOM   1274 C CD1 . TRP B 2  92  ? -26.990 17.736  -25.855 1.00 24.41 ? 96   TRP H CD1 1 
ATOM   1275 C CD2 . TRP B 2  92  ? -26.573 15.818  -24.778 1.00 24.84 ? 96   TRP H CD2 1 
ATOM   1276 N NE1 . TRP B 2  92  ? -26.876 18.025  -24.518 1.00 25.34 ? 96   TRP H NE1 1 
ATOM   1277 C CE2 . TRP B 2  92  ? -26.620 16.867  -23.833 1.00 26.14 ? 96   TRP H CE2 1 
ATOM   1278 C CE3 . TRP B 2  92  ? -26.324 14.514  -24.331 1.00 26.62 ? 96   TRP H CE3 1 
ATOM   1279 C CZ2 . TRP B 2  92  ? -26.427 16.653  -22.463 1.00 27.87 ? 96   TRP H CZ2 1 
ATOM   1280 C CZ3 . TRP B 2  92  ? -26.133 14.299  -22.966 1.00 27.33 ? 96   TRP H CZ3 1 
ATOM   1281 C CH2 . TRP B 2  92  ? -26.185 15.365  -22.050 1.00 27.28 ? 96   TRP H CH2 1 
ATOM   1282 N N   . ARG B 2  93  ? -29.399 14.121  -25.847 1.00 23.18 ? 97   ARG H N   1 
ATOM   1283 C CA  . ARG B 2  93  ? -29.762 13.057  -24.915 1.00 24.59 ? 97   ARG H CA  1 
ATOM   1284 C C   . ARG B 2  93  ? -30.715 12.025  -25.511 1.00 24.30 ? 97   ARG H C   1 
ATOM   1285 O O   . ARG B 2  93  ? -30.732 10.870  -25.077 1.00 24.42 ? 97   ARG H O   1 
ATOM   1286 C CB  . ARG B 2  93  ? -30.427 13.640  -23.661 1.00 26.67 ? 97   ARG H CB  1 
ATOM   1287 C CG  . ARG B 2  93  ? -29.526 14.443  -22.730 1.00 28.27 ? 97   ARG H CG  1 
ATOM   1288 C CD  . ARG B 2  93  ? -30.355 15.035  -21.589 1.00 32.67 ? 97   ARG H CD  1 
ATOM   1289 N NE  . ARG B 2  93  ? -29.581 15.905  -20.705 1.00 34.76 ? 97   ARG H NE  1 
ATOM   1290 C CZ  . ARG B 2  93  ? -28.737 15.472  -19.774 1.00 36.63 ? 97   ARG H CZ  1 
ATOM   1291 N NH1 . ARG B 2  93  ? -28.552 14.170  -19.590 1.00 36.33 ? 97   ARG H NH1 1 
ATOM   1292 N NH2 . ARG B 2  93  ? -28.072 16.346  -19.027 1.00 37.64 ? 97   ARG H NH2 1 
ATOM   1293 N N   . GLU B 2  94  A -31.502 12.421  -26.507 1.00 21.84 ? 97   GLU H N   1 
ATOM   1294 C CA  . GLU B 2  94  A -32.467 11.486  -27.061 1.00 22.68 ? 97   GLU H CA  1 
ATOM   1295 C C   . GLU B 2  94  A -32.421 11.146  -28.545 1.00 21.87 ? 97   GLU H C   1 
ATOM   1296 O O   . GLU B 2  94  A -32.076 10.028  -28.927 1.00 24.37 ? 97   GLU H O   1 
ATOM   1297 C CB  . GLU B 2  94  A -33.888 11.962  -26.733 1.00 24.00 ? 97   GLU H CB  1 
ATOM   1298 C CG  . GLU B 2  94  A -34.987 11.007  -27.211 1.00 27.06 ? 97   GLU H CG  1 
ATOM   1299 C CD  . GLU B 2  94  A -36.364 11.657  -27.295 1.00 28.61 ? 97   GLU H CD  1 
ATOM   1300 O OE1 . GLU B 2  94  A -37.310 10.985  -27.763 1.00 29.12 ? 97   GLU H OE1 1 
ATOM   1301 O OE2 . GLU B 2  94  A -36.505 12.835  -26.898 1.00 31.01 ? 97   GLU H OE2 1 
ATOM   1302 N N   . ASN B 2  95  ? -32.767 12.119  -29.378 1.00 19.91 ? 98   ASN H N   1 
ATOM   1303 C CA  . ASN B 2  95  ? -32.876 11.892  -30.814 1.00 17.57 ? 98   ASN H CA  1 
ATOM   1304 C C   . ASN B 2  95  ? -32.158 12.880  -31.734 1.00 17.29 ? 98   ASN H C   1 
ATOM   1305 O O   . ASN B 2  95  ? -32.418 12.898  -32.937 1.00 17.38 ? 98   ASN H O   1 
ATOM   1306 C CB  . ASN B 2  95  ? -34.357 11.901  -31.165 1.00 16.12 ? 98   ASN H CB  1 
ATOM   1307 C CG  . ASN B 2  95  ? -35.041 13.181  -30.712 1.00 16.29 ? 98   ASN H CG  1 
ATOM   1308 O OD1 . ASN B 2  95  ? -34.381 14.115  -30.239 1.00 16.03 ? 98   ASN H OD1 1 
ATOM   1309 N ND2 . ASN B 2  95  ? -36.355 13.238  -30.862 1.00 17.70 ? 98   ASN H ND2 1 
ATOM   1310 N N   . LEU B 2  96  ? -31.273 13.697  -31.176 1.00 16.68 ? 99   LEU H N   1 
ATOM   1311 C CA  . LEU B 2  96  ? -30.547 14.697  -31.960 1.00 17.16 ? 99   LEU H CA  1 
ATOM   1312 C C   . LEU B 2  96  ? -31.502 15.690  -32.632 1.00 17.57 ? 99   LEU H C   1 
ATOM   1313 O O   . LEU B 2  96  ? -31.247 16.180  -33.738 1.00 16.65 ? 99   LEU H O   1 
ATOM   1314 C CB  . LEU B 2  96  ? -29.661 14.015  -33.015 1.00 18.48 ? 99   LEU H CB  1 
ATOM   1315 C CG  . LEU B 2  96  ? -28.670 12.959  -32.508 1.00 19.36 ? 99   LEU H CG  1 
ATOM   1316 C CD1 . LEU B 2  96  ? -27.785 12.507  -33.665 1.00 18.99 ? 99   LEU H CD1 1 
ATOM   1317 C CD2 . LEU B 2  96  ? -27.813 13.528  -31.384 1.00 19.55 ? 99   LEU H CD2 1 
ATOM   1318 N N   . ASP B 2  97  ? -32.611 15.980  -31.960 1.00 16.34 ? 100  ASP H N   1 
ATOM   1319 C CA  . ASP B 2  97  ? -33.597 16.936  -32.467 1.00 16.14 ? 100  ASP H CA  1 
ATOM   1320 C C   . ASP B 2  97  ? -32.892 18.292  -32.564 1.00 13.69 ? 100  ASP H C   1 
ATOM   1321 O O   . ASP B 2  97  ? -32.067 18.623  -31.706 1.00 13.54 ? 100  ASP H O   1 
ATOM   1322 C CB  . ASP B 2  97  ? -34.783 17.012  -31.495 1.00 16.88 ? 100  ASP H CB  1 
ATOM   1323 C CG  . ASP B 2  97  ? -35.924 17.869  -32.010 1.00 18.72 ? 100  ASP H CG  1 
ATOM   1324 O OD1 . ASP B 2  97  ? -36.063 18.034  -33.239 1.00 16.00 ? 100  ASP H OD1 1 
ATOM   1325 O OD2 . ASP B 2  97  ? -36.709 18.368  -31.172 1.00 21.55 ? 100  ASP H OD2 1 
ATOM   1326 N N   . ARG B 2  98  ? -33.209 19.052  -33.611 1.00 13.73 ? 101  ARG H N   1 
ATOM   1327 C CA  . ARG B 2  98  ? -32.602 20.364  -33.853 1.00 13.80 ? 101  ARG H CA  1 
ATOM   1328 C C   . ARG B 2  98  ? -31.082 20.230  -33.984 1.00 14.04 ? 101  ARG H C   1 
ATOM   1329 O O   . ARG B 2  98  ? -30.317 20.915  -33.309 1.00 15.07 ? 101  ARG H O   1 
ATOM   1330 C CB  . ARG B 2  98  ? -32.955 21.332  -32.718 1.00 17.33 ? 101  ARG H CB  1 
ATOM   1331 C CG  . ARG B 2  98  ? -34.447 21.404  -32.425 1.00 20.33 ? 101  ARG H CG  1 
ATOM   1332 C CD  . ARG B 2  98  ? -34.775 22.493  -31.412 1.00 25.35 ? 101  ARG H CD  1 
ATOM   1333 N NE  . ARG B 2  98  ? -36.120 22.340  -30.861 1.00 29.76 ? 101  ARG H NE  1 
ATOM   1334 C CZ  . ARG B 2  98  ? -36.445 21.456  -29.920 1.00 31.00 ? 101  ARG H CZ  1 
ATOM   1335 N NH1 . ARG B 2  98  ? -35.523 20.645  -29.415 1.00 31.73 ? 101  ARG H NH1 1 
ATOM   1336 N NH2 . ARG B 2  98  ? -37.695 21.378  -29.485 1.00 32.77 ? 101  ARG H NH2 1 
ATOM   1337 N N   . ASP B 2  99  ? -30.659 19.332  -34.870 1.00 11.98 ? 102  ASP H N   1 
ATOM   1338 C CA  . ASP B 2  99  ? -29.247 19.056  -35.107 1.00 12.79 ? 102  ASP H CA  1 
ATOM   1339 C C   . ASP B 2  99  ? -28.727 20.105  -36.072 1.00 13.85 ? 102  ASP H C   1 
ATOM   1340 O O   . ASP B 2  99  ? -28.583 19.862  -37.271 1.00 12.22 ? 102  ASP H O   1 
ATOM   1341 C CB  . ASP B 2  99  ? -29.106 17.651  -35.701 1.00 12.23 ? 102  ASP H CB  1 
ATOM   1342 C CG  . ASP B 2  99  ? -27.666 17.168  -35.741 1.00 13.93 ? 102  ASP H CG  1 
ATOM   1343 O OD1 . ASP B 2  99  ? -26.783 17.817  -35.141 1.00 13.75 ? 102  ASP H OD1 1 
ATOM   1344 O OD2 . ASP B 2  99  ? -27.425 16.117  -36.373 1.00 13.31 ? 102  ASP H OD2 1 
ATOM   1345 N N   . ILE B 2  100 ? -28.446 21.287  -35.539 1.00 12.90 ? 103  ILE H N   1 
ATOM   1346 C CA  . ILE B 2  100 ? -27.995 22.375  -36.383 1.00 11.82 ? 103  ILE H CA  1 
ATOM   1347 C C   . ILE B 2  100 ? -27.052 23.304  -35.641 1.00 12.71 ? 103  ILE H C   1 
ATOM   1348 O O   . ILE B 2  100 ? -27.177 23.505  -34.427 1.00 11.96 ? 103  ILE H O   1 
ATOM   1349 C CB  . ILE B 2  100 ? -29.218 23.176  -36.897 1.00 11.49 ? 103  ILE H CB  1 
ATOM   1350 C CG1 . ILE B 2  100 ? -28.784 24.270  -37.874 1.00 12.20 ? 103  ILE H CG1 1 
ATOM   1351 C CG2 . ILE B 2  100 ? -29.967 23.786  -35.713 1.00 12.18 ? 103  ILE H CG2 1 
ATOM   1352 C CD1 . ILE B 2  100 ? -29.951 24.922  -38.614 1.00 14.76 ? 103  ILE H CD1 1 
ATOM   1353 N N   . ALA B 2  101 ? -26.094 23.847  -36.382 1.00 12.90 ? 104  ALA H N   1 
ATOM   1354 C CA  . ALA B 2  101 ? -25.128 24.794  -35.833 1.00 12.55 ? 104  ALA H CA  1 
ATOM   1355 C C   . ALA B 2  101 ? -24.720 25.774  -36.916 1.00 13.61 ? 104  ALA H C   1 
ATOM   1356 O O   . ALA B 2  101 ? -24.648 25.431  -38.096 1.00 11.87 ? 104  ALA H O   1 
ATOM   1357 C CB  . ALA B 2  101 ? -23.899 24.067  -35.309 1.00 13.88 ? 104  ALA H CB  1 
ATOM   1358 N N   . LEU B 2  102 ? -24.480 27.016  -36.511 1.00 11.53 ? 105  LEU H N   1 
ATOM   1359 C CA  . LEU B 2  102 ? -24.036 28.044  -37.439 1.00 13.22 ? 105  LEU H CA  1 
ATOM   1360 C C   . LEU B 2  102 ? -22.608 28.396  -37.075 1.00 12.79 ? 105  LEU H C   1 
ATOM   1361 O O   . LEU B 2  102 ? -22.246 28.411  -35.899 1.00 13.67 ? 105  LEU H O   1 
ATOM   1362 C CB  . LEU B 2  102 ? -24.911 29.290  -37.331 1.00 12.02 ? 105  LEU H CB  1 
ATOM   1363 C CG  . LEU B 2  102 ? -26.189 29.259  -38.171 1.00 13.63 ? 105  LEU H CG  1 
ATOM   1364 C CD1 . LEU B 2  102 ? -27.169 30.320  -37.663 1.00 15.65 ? 105  LEU H CD1 1 
ATOM   1365 C CD2 . LEU B 2  102 ? -25.839 29.494  -39.641 1.00 15.55 ? 105  LEU H CD2 1 
ATOM   1366 N N   . MET B 2  103 ? -21.798 28.659  -38.091 1.00 12.15 ? 106  MET H N   1 
ATOM   1367 C CA  . MET B 2  103 ? -20.409 29.018  -37.876 1.00 13.51 ? 106  MET H CA  1 
ATOM   1368 C C   . MET B 2  103 ? -20.107 30.286  -38.665 1.00 12.18 ? 106  MET H C   1 
ATOM   1369 O O   . MET B 2  103 ? -20.374 30.375  -39.865 1.00 12.32 ? 106  MET H O   1 
ATOM   1370 C CB  . MET B 2  103 ? -19.495 27.870  -38.315 1.00 14.24 ? 106  MET H CB  1 
ATOM   1371 C CG  . MET B 2  103 ? -19.771 26.574  -37.568 1.00 16.63 ? 106  MET H CG  1 
ATOM   1372 S SD  . MET B 2  103 ? -18.629 25.246  -37.993 1.00 19.09 ? 106  MET H SD  1 
ATOM   1373 C CE  . MET B 2  103 ? -19.022 25.047  -39.699 1.00 16.96 ? 106  MET H CE  1 
ATOM   1374 N N   . LYS B 2  104 ? -19.560 31.273  -37.967 1.00 14.62 ? 107  LYS H N   1 
ATOM   1375 C CA  . LYS B 2  104 ? -19.223 32.552  -38.578 1.00 15.33 ? 107  LYS H CA  1 
ATOM   1376 C C   . LYS B 2  104 ? -17.741 32.563  -38.932 1.00 15.84 ? 107  LYS H C   1 
ATOM   1377 O O   . LYS B 2  104 ? -16.894 32.279  -38.088 1.00 16.87 ? 107  LYS H O   1 
ATOM   1378 C CB  . LYS B 2  104 ? -19.542 33.685  -37.594 1.00 14.82 ? 107  LYS H CB  1 
ATOM   1379 C CG  . LYS B 2  104 ? -19.295 35.079  -38.131 1.00 16.83 ? 107  LYS H CG  1 
ATOM   1380 C CD  . LYS B 2  104 ? -19.643 36.124  -37.079 1.00 17.16 ? 107  LYS H CD  1 
ATOM   1381 C CE  . LYS B 2  104 ? -19.332 37.515  -37.582 1.00 19.30 ? 107  LYS H CE  1 
ATOM   1382 N NZ  . LYS B 2  104 ? -19.550 38.535  -36.517 1.00 19.86 ? 107  LYS H NZ  1 
ATOM   1383 N N   . LEU B 2  105 ? -17.436 32.886  -40.185 1.00 14.88 ? 108  LEU H N   1 
ATOM   1384 C CA  . LEU B 2  105 ? -16.053 32.920  -40.649 1.00 16.32 ? 108  LEU H CA  1 
ATOM   1385 C C   . LEU B 2  105 ? -15.312 34.109  -40.064 1.00 18.80 ? 108  LEU H C   1 
ATOM   1386 O O   . LEU B 2  105 ? -15.874 35.199  -39.938 1.00 20.98 ? 108  LEU H O   1 
ATOM   1387 C CB  . LEU B 2  105 ? -16.015 32.991  -42.175 1.00 17.45 ? 108  LEU H CB  1 
ATOM   1388 C CG  . LEU B 2  105 ? -16.770 31.866  -42.890 1.00 14.43 ? 108  LEU H CG  1 
ATOM   1389 C CD1 . LEU B 2  105 ? -16.657 32.053  -44.390 1.00 16.31 ? 108  LEU H CD1 1 
ATOM   1390 C CD2 . LEU B 2  105 ? -16.209 30.519  -42.471 1.00 18.73 ? 108  LEU H CD2 1 
ATOM   1391 N N   . LYS B 2  106 ? -14.049 33.892  -39.705 1.00 21.60 ? 109  LYS H N   1 
ATOM   1392 C CA  . LYS B 2  106 ? -13.222 34.944  -39.127 1.00 25.28 ? 109  LYS H CA  1 
ATOM   1393 C C   . LYS B 2  106 ? -13.063 36.076  -40.135 1.00 27.10 ? 109  LYS H C   1 
ATOM   1394 O O   . LYS B 2  106 ? -12.986 37.249  -39.770 1.00 29.51 ? 109  LYS H O   1 
ATOM   1395 C CB  . LYS B 2  106 ? -11.859 34.376  -38.731 1.00 25.87 ? 109  LYS H CB  1 
ATOM   1396 C CG  . LYS B 2  106 ? -11.032 35.298  -37.854 1.00 29.13 ? 109  LYS H CG  1 
ATOM   1397 C CD  . LYS B 2  106 ? -9.877  34.537  -37.217 1.00 32.41 ? 109  LYS H CD  1 
ATOM   1398 C CE  . LYS B 2  106 ? -9.051  35.432  -36.307 1.00 34.68 ? 109  LYS H CE  1 
ATOM   1399 N NZ  . LYS B 2  106 ? -7.980  34.668  -35.608 1.00 37.34 ? 109  LYS H NZ  1 
ATOM   1400 N N   . LYS B 2  107 ? -13.015 35.712  -41.410 1.00 27.68 ? 110  LYS H N   1 
ATOM   1401 C CA  . LYS B 2  107 ? -12.903 36.687  -42.482 1.00 28.83 ? 110  LYS H CA  1 
ATOM   1402 C C   . LYS B 2  107 ? -13.755 36.191  -43.648 1.00 27.26 ? 110  LYS H C   1 
ATOM   1403 O O   . LYS B 2  107 ? -13.716 35.015  -44.002 1.00 27.91 ? 110  LYS H O   1 
ATOM   1404 C CB  . LYS B 2  107 ? -11.442 36.846  -42.918 1.00 29.24 ? 110  LYS H CB  1 
ATOM   1405 C CG  . LYS B 2  107 ? -10.802 35.573  -43.451 1.00 30.55 ? 110  LYS H CG  1 
ATOM   1406 N N   . PRO B 2  108 ? -14.542 37.085  -44.254 1.00 27.17 ? 111  PRO H N   1 
ATOM   1407 C CA  . PRO B 2  108 ? -15.389 36.680  -45.379 1.00 25.24 ? 111  PRO H CA  1 
ATOM   1408 C C   . PRO B 2  108 ? -14.607 35.994  -46.494 1.00 23.63 ? 111  PRO H C   1 
ATOM   1409 O O   . PRO B 2  108 ? -13.468 36.365  -46.782 1.00 22.13 ? 111  PRO H O   1 
ATOM   1410 C CB  . PRO B 2  108 ? -16.011 37.999  -45.831 1.00 26.65 ? 111  PRO H CB  1 
ATOM   1411 C CG  . PRO B 2  108 ? -14.953 39.014  -45.457 1.00 28.62 ? 111  PRO H CG  1 
ATOM   1412 C CD  . PRO B 2  108 ? -14.560 38.548  -44.083 1.00 27.99 ? 111  PRO H CD  1 
ATOM   1413 N N   A VAL B 2  109 ? -15.213 34.984  -47.110 0.34 21.93 ? 112  VAL H N   1 
ATOM   1414 N N   B VAL B 2  109 ? -15.223 34.989  -47.110 0.66 21.26 ? 112  VAL H N   1 
ATOM   1415 C CA  A VAL B 2  109 ? -14.566 34.264  -48.200 0.34 20.62 ? 112  VAL H CA  1 
ATOM   1416 C CA  B VAL B 2  109 ? -14.591 34.256  -48.199 0.66 19.51 ? 112  VAL H CA  1 
ATOM   1417 C C   A VAL B 2  109 ? -14.992 34.866  -49.534 0.28 19.95 ? 112  VAL H C   1 
ATOM   1418 C C   B VAL B 2  109 ? -14.999 34.873  -49.538 0.64 18.70 ? 112  VAL H C   1 
ATOM   1419 O O   A VAL B 2  109 ? -16.151 35.242  -49.714 0.15 19.67 ? 112  VAL H O   1 
ATOM   1420 O O   B VAL B 2  109 ? -16.148 35.282  -49.725 0.85 16.99 ? 112  VAL H O   1 
ATOM   1421 C CB  A VAL B 2  109 ? -14.935 32.764  -48.186 0.34 19.97 ? 112  VAL H CB  1 
ATOM   1422 C CB  B VAL B 2  109 ? -14.997 32.756  -48.166 0.66 18.26 ? 112  VAL H CB  1 
ATOM   1423 C CG1 A VAL B 2  109 ? -14.297 32.057  -49.373 0.10 20.19 ? 112  VAL H CG1 1 
ATOM   1424 C CG1 B VAL B 2  109 ? -16.484 32.604  -48.497 0.90 17.38 ? 112  VAL H CG1 1 
ATOM   1425 C CG2 A VAL B 2  109 ? -14.472 32.131  -46.888 0.42 19.53 ? 112  VAL H CG2 1 
ATOM   1426 C CG2 B VAL B 2  109 ? -14.132 31.952  -49.128 0.58 18.90 ? 112  VAL H CG2 1 
ATOM   1427 N N   . ALA B 2  110 ? -14.050 34.957  -50.466 1.00 19.38 ? 113  ALA H N   1 
ATOM   1428 C CA  . ALA B 2  110 ? -14.331 35.521  -51.781 1.00 19.15 ? 113  ALA H CA  1 
ATOM   1429 C C   . ALA B 2  110 ? -14.993 34.464  -52.653 1.00 16.89 ? 113  ALA H C   1 
ATOM   1430 O O   . ALA B 2  110 ? -14.570 33.309  -52.655 1.00 16.92 ? 113  ALA H O   1 
ATOM   1431 C CB  . ALA B 2  110 ? -13.032 36.002  -52.440 1.00 21.00 ? 113  ALA H CB  1 
ATOM   1432 N N   . PHE B 2  111 ? -16.030 34.853  -53.387 1.00 17.32 ? 114  PHE H N   1 
ATOM   1433 C CA  . PHE B 2  111 ? -16.702 33.903  -54.261 1.00 16.65 ? 114  PHE H CA  1 
ATOM   1434 C C   . PHE B 2  111 ? -15.899 33.731  -55.539 1.00 17.10 ? 114  PHE H C   1 
ATOM   1435 O O   . PHE B 2  111 ? -15.082 34.583  -55.902 1.00 18.75 ? 114  PHE H O   1 
ATOM   1436 C CB  . PHE B 2  111 ? -18.124 34.360  -54.605 1.00 17.10 ? 114  PHE H CB  1 
ATOM   1437 C CG  . PHE B 2  111 ? -19.002 34.554  -53.405 1.00 16.25 ? 114  PHE H CG  1 
ATOM   1438 C CD1 . PHE B 2  111 ? -18.866 33.739  -52.283 1.00 15.04 ? 114  PHE H CD1 1 
ATOM   1439 C CD2 . PHE B 2  111 ? -19.981 35.546  -53.398 1.00 17.14 ? 114  PHE H CD2 1 
ATOM   1440 C CE1 . PHE B 2  111 ? -19.691 33.913  -51.173 1.00 15.95 ? 114  PHE H CE1 1 
ATOM   1441 C CE2 . PHE B 2  111 ? -20.811 35.723  -52.291 1.00 18.41 ? 114  PHE H CE2 1 
ATOM   1442 C CZ  . PHE B 2  111 ? -20.665 34.904  -51.178 1.00 17.13 ? 114  PHE H CZ  1 
ATOM   1443 N N   . SER B 2  112 ? -16.133 32.615  -56.211 1.00 16.16 ? 115  SER H N   1 
ATOM   1444 C CA  . SER B 2  112 ? -15.439 32.296  -57.448 1.00 15.68 ? 115  SER H CA  1 
ATOM   1445 C C   . SER B 2  112 ? -16.283 31.272  -58.194 1.00 17.26 ? 115  SER H C   1 
ATOM   1446 O O   . SER B 2  112 ? -17.434 31.015  -57.832 1.00 16.58 ? 115  SER H O   1 
ATOM   1447 C CB  . SER B 2  112 ? -14.073 31.678  -57.133 1.00 17.16 ? 115  SER H CB  1 
ATOM   1448 O OG  . SER B 2  112 ? -14.230 30.397  -56.524 1.00 18.13 ? 115  SER H OG  1 
ATOM   1449 N N   . ASP B 2  113 ? -15.710 30.686  -59.237 1.00 17.21 ? 116  ASP H N   1 
ATOM   1450 C CA  . ASP B 2  113 ? -16.422 29.666  -59.992 1.00 18.33 ? 116  ASP H CA  1 
ATOM   1451 C C   . ASP B 2  113 ? -16.623 28.428  -59.122 1.00 16.90 ? 116  ASP H C   1 
ATOM   1452 O O   . ASP B 2  113 ? -17.498 27.614  -59.401 1.00 16.77 ? 116  ASP H O   1 
ATOM   1453 C CB  . ASP B 2  113 ? -15.632 29.253  -61.239 1.00 20.11 ? 116  ASP H CB  1 
ATOM   1454 C CG  . ASP B 2  113 ? -15.686 30.292  -62.342 1.00 23.63 ? 116  ASP H CG  1 
ATOM   1455 O OD1 . ASP B 2  113 ? -16.456 31.267  -62.220 1.00 23.43 ? 116  ASP H OD1 1 
ATOM   1456 O OD2 . ASP B 2  113 ? -14.958 30.125  -63.341 1.00 23.80 ? 116  ASP H OD2 1 
ATOM   1457 N N   . TYR B 2  114 ? -15.821 28.306  -58.066 1.00 14.78 ? 117  TYR H N   1 
ATOM   1458 C CA  . TYR B 2  114 ? -15.870 27.144  -57.178 1.00 14.42 ? 117  TYR H CA  1 
ATOM   1459 C C   . TYR B 2  114 ? -16.465 27.382  -55.800 1.00 13.75 ? 117  TYR H C   1 
ATOM   1460 O O   . TYR B 2  114 ? -16.696 26.431  -55.053 1.00 14.35 ? 117  TYR H O   1 
ATOM   1461 C CB  . TYR B 2  114 ? -14.460 26.600  -56.992 1.00 15.80 ? 117  TYR H CB  1 
ATOM   1462 C CG  . TYR B 2  114 ? -13.695 26.527  -58.286 1.00 18.32 ? 117  TYR H CG  1 
ATOM   1463 C CD1 . TYR B 2  114 ? -13.884 25.467  -59.170 1.00 19.31 ? 117  TYR H CD1 1 
ATOM   1464 C CD2 . TYR B 2  114 ? -12.818 27.545  -58.649 1.00 20.57 ? 117  TYR H CD2 1 
ATOM   1465 C CE1 . TYR B 2  114 ? -13.211 25.422  -60.393 1.00 22.71 ? 117  TYR H CE1 1 
ATOM   1466 C CE2 . TYR B 2  114 ? -12.146 27.512  -59.864 1.00 21.71 ? 117  TYR H CE2 1 
ATOM   1467 C CZ  . TYR B 2  114 ? -12.345 26.451  -60.730 1.00 24.52 ? 117  TYR H CZ  1 
ATOM   1468 O OH  . TYR B 2  114 ? -11.673 26.421  -61.931 1.00 26.22 ? 117  TYR H OH  1 
ATOM   1469 N N   . ILE B 2  115 ? -16.693 28.646  -55.465 1.00 14.40 ? 118  ILE H N   1 
ATOM   1470 C CA  . ILE B 2  115 ? -17.230 29.025  -54.162 1.00 15.71 ? 118  ILE H CA  1 
ATOM   1471 C C   . ILE B 2  115 ? -18.416 29.946  -54.393 1.00 15.95 ? 118  ILE H C   1 
ATOM   1472 O O   . ILE B 2  115 ? -18.265 31.036  -54.940 1.00 15.84 ? 118  ILE H O   1 
ATOM   1473 C CB  . ILE B 2  115 ? -16.157 29.765  -53.335 1.00 14.75 ? 118  ILE H CB  1 
ATOM   1474 C CG1 . ILE B 2  115 ? -14.942 28.850  -53.143 1.00 15.33 ? 118  ILE H CG1 1 
ATOM   1475 C CG2 . ILE B 2  115 ? -16.738 30.210  -51.997 1.00 15.37 ? 118  ILE H CG2 1 
ATOM   1476 C CD1 . ILE B 2  115 ? -13.818 29.444  -52.299 1.00 13.64 ? 118  ILE H CD1 1 
ATOM   1477 N N   . HIS B 2  116 ? -19.597 29.506  -53.976 1.00 12.20 ? 119  HIS H N   1 
ATOM   1478 C CA  . HIS B 2  116 ? -20.817 30.281  -54.184 1.00 12.93 ? 119  HIS H CA  1 
ATOM   1479 C C   . HIS B 2  116 ? -21.845 29.766  -53.185 1.00 12.95 ? 119  HIS H C   1 
ATOM   1480 O O   . HIS B 2  116 ? -21.983 28.552  -52.998 1.00 11.37 ? 119  HIS H O   1 
ATOM   1481 C CB  . HIS B 2  116 ? -21.327 30.067  -55.617 1.00 13.33 ? 119  HIS H CB  1 
ATOM   1482 C CG  . HIS B 2  116 ? -22.329 31.085  -56.065 1.00 17.07 ? 119  HIS H CG  1 
ATOM   1483 N ND1 . HIS B 2  116 ? -21.969 32.256  -56.699 1.00 16.96 ? 119  HIS H ND1 1 
ATOM   1484 C CD2 . HIS B 2  116 ? -23.678 31.121  -55.947 1.00 16.33 ? 119  HIS H CD2 1 
ATOM   1485 C CE1 . HIS B 2  116 ? -23.052 32.969  -56.952 1.00 17.81 ? 119  HIS H CE1 1 
ATOM   1486 N NE2 . HIS B 2  116 ? -24.103 32.304  -56.506 1.00 16.92 ? 119  HIS H NE2 1 
ATOM   1487 N N   . PRO B 2  117 ? -22.600 30.671  -52.547 1.00 10.17 ? 120  PRO H N   1 
ATOM   1488 C CA  . PRO B 2  117 ? -23.588 30.206  -51.573 1.00 11.68 ? 120  PRO H CA  1 
ATOM   1489 C C   . PRO B 2  117 ? -24.859 29.596  -52.126 1.00 9.69  ? 120  PRO H C   1 
ATOM   1490 O O   . PRO B 2  117 ? -25.305 29.908  -53.245 1.00 10.24 ? 120  PRO H O   1 
ATOM   1491 C CB  . PRO B 2  117 ? -23.867 31.460  -50.745 1.00 12.59 ? 120  PRO H CB  1 
ATOM   1492 C CG  . PRO B 2  117 ? -23.761 32.546  -51.778 1.00 13.61 ? 120  PRO H CG  1 
ATOM   1493 C CD  . PRO B 2  117 ? -22.532 32.145  -52.575 1.00 12.63 ? 120  PRO H CD  1 
ATOM   1494 N N   . VAL B 2  118 ? -25.438 28.712  -51.319 1.00 11.00 ? 121  VAL H N   1 
ATOM   1495 C CA  . VAL B 2  118 ? -26.682 28.046  -51.661 1.00 10.25 ? 121  VAL H CA  1 
ATOM   1496 C C   . VAL B 2  118 ? -27.800 28.895  -51.042 1.00 11.81 ? 121  VAL H C   1 
ATOM   1497 O O   . VAL B 2  118 ? -27.549 29.703  -50.137 1.00 13.01 ? 121  VAL H O   1 
ATOM   1498 C CB  . VAL B 2  118 ? -26.698 26.606  -51.062 1.00 10.79 ? 121  VAL H CB  1 
ATOM   1499 C CG1 . VAL B 2  118 ? -26.782 26.673  -49.539 1.00 10.48 ? 121  VAL H CG1 1 
ATOM   1500 C CG2 . VAL B 2  118 ? -27.838 25.784  -51.667 1.00 11.82 ? 121  VAL H CG2 1 
ATOM   1501 N N   . CYS B 2  119 ? -29.024 28.740  -51.534 1.00 9.83  ? 122  CYS H N   1 
ATOM   1502 C CA  . CYS B 2  119 ? -30.140 29.499  -50.970 1.00 9.89  ? 122  CYS H CA  1 
ATOM   1503 C C   . CYS B 2  119 ? -30.819 28.748  -49.841 1.00 10.17 ? 122  CYS H C   1 
ATOM   1504 O O   . CYS B 2  119 ? -30.826 27.520  -49.819 1.00 10.68 ? 122  CYS H O   1 
ATOM   1505 C CB  . CYS B 2  119 ? -31.228 29.752  -52.006 1.00 10.64 ? 122  CYS H CB  1 
ATOM   1506 S SG  . CYS B 2  119 ? -30.778 30.633  -53.517 1.00 10.63 ? 122  CYS H SG  1 
ATOM   1507 N N   . LEU B 2  120 ? -31.400 29.495  -48.906 1.00 11.68 ? 123  LEU H N   1 
ATOM   1508 C CA  . LEU B 2  120 ? -32.186 28.891  -47.835 1.00 11.80 ? 123  LEU H CA  1 
ATOM   1509 C C   . LEU B 2  120 ? -33.619 29.146  -48.290 1.00 11.78 ? 123  LEU H C   1 
ATOM   1510 O O   . LEU B 2  120 ? -33.942 30.226  -48.802 1.00 12.91 ? 123  LEU H O   1 
ATOM   1511 C CB  . LEU B 2  120 ? -31.925 29.549  -46.483 1.00 11.62 ? 123  LEU H CB  1 
ATOM   1512 C CG  . LEU B 2  120 ? -30.528 29.312  -45.919 1.00 14.16 ? 123  LEU H CG  1 
ATOM   1513 C CD1 . LEU B 2  120 ? -30.469 29.799  -44.478 1.00 17.27 ? 123  LEU H CD1 1 
ATOM   1514 C CD2 . LEU B 2  120 ? -30.201 27.829  -45.986 1.00 16.18 ? 123  LEU H CD2 1 
ATOM   1515 N N   . PRO B 2  121 ? -34.502 28.159  -48.109 1.00 11.73 ? 124  PRO H N   1 
ATOM   1516 C CA  . PRO B 2  121 ? -35.897 28.272  -48.523 1.00 13.65 ? 124  PRO H CA  1 
ATOM   1517 C C   . PRO B 2  121 ? -36.837 29.205  -47.790 1.00 14.67 ? 124  PRO H C   1 
ATOM   1518 O O   . PRO B 2  121 ? -36.727 29.426  -46.583 1.00 16.13 ? 124  PRO H O   1 
ATOM   1519 C CB  . PRO B 2  121 ? -36.388 26.832  -48.433 1.00 11.75 ? 124  PRO H CB  1 
ATOM   1520 C CG  . PRO B 2  121 ? -35.680 26.340  -47.237 1.00 11.81 ? 124  PRO H CG  1 
ATOM   1521 C CD  . PRO B 2  121 ? -34.261 26.845  -47.487 1.00 11.13 ? 124  PRO H CD  1 
ATOM   1522 N N   . ASP B 2  122 ? -37.765 29.741  -48.575 1.00 16.53 ? 125  ASP H N   1 
ATOM   1523 C CA  . ASP B 2  122 ? -38.832 30.597  -48.083 1.00 18.03 ? 125  ASP H CA  1 
ATOM   1524 C C   . ASP B 2  122 ? -39.942 29.575  -47.857 1.00 19.13 ? 125  ASP H C   1 
ATOM   1525 O O   . ASP B 2  122 ? -39.834 28.429  -48.314 1.00 17.60 ? 125  ASP H O   1 
ATOM   1526 C CB  . ASP B 2  122 ? -39.231 31.614  -49.153 1.00 17.94 ? 125  ASP H CB  1 
ATOM   1527 C CG  . ASP B 2  122 ? -39.592 30.962  -50.473 1.00 18.70 ? 125  ASP H CG  1 
ATOM   1528 O OD1 . ASP B 2  122 ? -40.796 30.732  -50.720 1.00 21.09 ? 125  ASP H OD1 1 
ATOM   1529 O OD2 . ASP B 2  122 ? -38.670 30.670  -51.268 1.00 19.62 ? 125  ASP H OD2 1 
ATOM   1530 N N   . ARG B 2  123 ? -41.007 29.973  -47.173 1.00 17.40 ? 126  ARG H N   1 
ATOM   1531 C CA  . ARG B 2  123 ? -42.100 29.055  -46.875 1.00 19.17 ? 126  ARG H CA  1 
ATOM   1532 C C   . ARG B 2  123 ? -42.703 28.353  -48.083 1.00 17.17 ? 126  ARG H C   1 
ATOM   1533 O O   . ARG B 2  123 ? -42.949 27.142  -48.040 1.00 17.30 ? 126  ARG H O   1 
ATOM   1534 C CB  . ARG B 2  123 ? -43.207 29.788  -46.112 1.00 20.28 ? 126  ARG H CB  1 
ATOM   1535 C CG  . ARG B 2  123 ? -44.319 28.877  -45.618 1.00 23.78 ? 126  ARG H CG  1 
ATOM   1536 C CD  . ARG B 2  123 ? -45.376 29.670  -44.858 1.00 29.03 ? 126  ARG H CD  1 
ATOM   1537 N NE  . ARG B 2  123 ? -44.817 30.341  -43.685 1.00 32.36 ? 126  ARG H NE  1 
ATOM   1538 C CZ  . ARG B 2  123 ? -44.464 29.720  -42.563 1.00 32.34 ? 126  ARG H CZ  1 
ATOM   1539 N NH1 . ARG B 2  123 ? -44.613 28.408  -42.450 1.00 34.09 ? 126  ARG H NH1 1 
ATOM   1540 N NH2 . ARG B 2  123 ? -43.957 30.413  -41.554 1.00 35.97 ? 126  ARG H NH2 1 
ATOM   1541 N N   . GLU B 2  124 ? -42.949 29.104  -49.152 1.00 16.65 ? 127  GLU H N   1 
ATOM   1542 C CA  . GLU B 2  124 ? -43.541 28.541  -50.356 1.00 17.11 ? 127  GLU H CA  1 
ATOM   1543 C C   . GLU B 2  124 ? -42.625 27.526  -51.027 1.00 16.75 ? 127  GLU H C   1 
ATOM   1544 O O   . GLU B 2  124 ? -43.067 26.456  -51.445 1.00 15.83 ? 127  GLU H O   1 
ATOM   1545 C CB  . GLU B 2  124 ? -43.890 29.653  -51.345 1.00 21.18 ? 127  GLU H CB  1 
ATOM   1546 C CG  . GLU B 2  124 ? -44.605 29.163  -52.585 1.00 23.29 ? 127  GLU H CG  1 
ATOM   1547 C CD  . GLU B 2  124 ? -44.932 30.286  -53.541 1.00 27.83 ? 127  GLU H CD  1 
ATOM   1548 O OE1 . GLU B 2  124 ? -43.992 30.969  -53.999 1.00 30.02 ? 127  GLU H OE1 1 
ATOM   1549 O OE2 . GLU B 2  124 ? -46.130 30.489  -53.832 1.00 29.04 ? 127  GLU H OE2 1 
ATOM   1550 N N   . THR B 2  125 ? -41.346 27.854  -51.135 1.00 16.69 ? 128  THR H N   1 
ATOM   1551 C CA  . THR B 2  125 ? -40.410 26.926  -51.759 1.00 17.34 ? 128  THR H CA  1 
ATOM   1552 C C   . THR B 2  125 ? -40.312 25.623  -50.960 1.00 17.48 ? 128  THR H C   1 
ATOM   1553 O O   . THR B 2  125 ? -40.281 24.526  -51.534 1.00 18.13 ? 128  THR H O   1 
ATOM   1554 C CB  . THR B 2  125 ? -39.018 27.566  -51.896 1.00 17.81 ? 128  THR H CB  1 
ATOM   1555 O OG1 . THR B 2  125 ? -39.100 28.677  -52.798 1.00 16.55 ? 128  THR H OG1 1 
ATOM   1556 C CG2 . THR B 2  125 ? -38.012 26.546  -52.432 1.00 17.39 ? 128  THR H CG2 1 
ATOM   1557 N N   . ALA B 2  126 ? -40.281 25.735  -49.636 1.00 16.42 ? 129  ALA H N   1 
ATOM   1558 C CA  . ALA B 2  126 ? -40.193 24.554  -48.783 1.00 16.68 ? 129  ALA H CA  1 
ATOM   1559 C C   . ALA B 2  126 ? -41.441 23.692  -48.934 1.00 17.76 ? 129  ALA H C   1 
ATOM   1560 O O   . ALA B 2  126 ? -41.352 22.467  -49.048 1.00 15.69 ? 129  ALA H O   1 
ATOM   1561 C CB  . ALA B 2  126 ? -40.012 24.963  -47.327 1.00 17.74 ? 129  ALA H CB  1 
ATOM   1562 N N   . ALA B 2  127 A -42.608 24.333  -48.944 1.00 15.74 ? 129  ALA H N   1 
ATOM   1563 C CA  . ALA B 2  127 A -43.863 23.603  -49.084 1.00 16.69 ? 129  ALA H CA  1 
ATOM   1564 C C   . ALA B 2  127 A -43.937 22.931  -50.449 1.00 15.30 ? 129  ALA H C   1 
ATOM   1565 O O   . ALA B 2  127 A -44.410 21.797  -50.574 1.00 15.59 ? 129  ALA H O   1 
ATOM   1566 C CB  . ALA B 2  127 A -45.048 24.558  -48.903 1.00 16.02 ? 129  ALA H CB  1 
ATOM   1567 N N   . SER B 2  128 B -43.440 23.632  -51.462 1.00 15.48 ? 129  SER H N   1 
ATOM   1568 C CA  . SER B 2  128 B -43.454 23.149  -52.835 1.00 16.72 ? 129  SER H CA  1 
ATOM   1569 C C   . SER B 2  128 B -42.457 22.040  -53.140 1.00 16.60 ? 129  SER H C   1 
ATOM   1570 O O   . SER B 2  128 B -42.767 21.115  -53.893 1.00 18.38 ? 129  SER H O   1 
ATOM   1571 C CB  . SER B 2  128 B -43.193 24.316  -53.793 1.00 17.89 ? 129  SER H CB  1 
ATOM   1572 O OG  . SER B 2  128 B -44.236 25.271  -53.730 1.00 21.55 ? 129  SER H OG  1 
ATOM   1573 N N   . LEU B 2  129 C -41.264 22.133  -52.563 1.00 13.93 ? 129  LEU H N   1 
ATOM   1574 C CA  . LEU B 2  129 C -40.224 21.148  -52.838 1.00 15.95 ? 129  LEU H CA  1 
ATOM   1575 C C   . LEU B 2  129 C -40.067 19.991  -51.859 1.00 15.17 ? 129  LEU H C   1 
ATOM   1576 O O   . LEU B 2  129 C -39.807 18.857  -52.276 1.00 13.62 ? 129  LEU H O   1 
ATOM   1577 C CB  . LEU B 2  129 C -38.871 21.849  -52.983 1.00 14.07 ? 129  LEU H CB  1 
ATOM   1578 C CG  . LEU B 2  129 C -38.749 22.966  -54.023 1.00 16.44 ? 129  LEU H CG  1 
ATOM   1579 C CD1 . LEU B 2  129 C -37.291 23.398  -54.094 1.00 17.34 ? 129  LEU H CD1 1 
ATOM   1580 C CD2 . LEU B 2  129 C -39.225 22.493  -55.388 1.00 16.35 ? 129  LEU H CD2 1 
ATOM   1581 N N   . LEU B 2  130 ? -40.206 20.253  -50.565 1.00 15.33 ? 130  LEU H N   1 
ATOM   1582 C CA  . LEU B 2  130 ? -40.029 19.179  -49.597 1.00 14.38 ? 130  LEU H CA  1 
ATOM   1583 C C   . LEU B 2  130 ? -41.259 18.282  -49.504 1.00 15.41 ? 130  LEU H C   1 
ATOM   1584 O O   . LEU B 2  130 ? -42.002 18.321  -48.520 1.00 18.18 ? 130  LEU H O   1 
ATOM   1585 C CB  . LEU B 2  130 ? -39.686 19.747  -48.217 1.00 15.55 ? 130  LEU H CB  1 
ATOM   1586 C CG  . LEU B 2  130 ? -39.000 18.740  -47.294 1.00 17.67 ? 130  LEU H CG  1 
ATOM   1587 C CD1 . LEU B 2  130 ? -37.586 18.470  -47.805 1.00 18.45 ? 130  LEU H CD1 1 
ATOM   1588 C CD2 . LEU B 2  130 ? -38.955 19.275  -45.868 1.00 19.13 ? 130  LEU H CD2 1 
ATOM   1589 N N   . GLN B 2  131 ? -41.450 17.454  -50.530 1.00 15.63 ? 131  GLN H N   1 
ATOM   1590 C CA  . GLN B 2  131 ? -42.587 16.541  -50.587 1.00 17.42 ? 131  GLN H CA  1 
ATOM   1591 C C   . GLN B 2  131 ? -42.151 15.118  -50.911 1.00 17.92 ? 131  GLN H C   1 
ATOM   1592 O O   . GLN B 2  131 ? -41.223 14.903  -51.690 1.00 14.62 ? 131  GLN H O   1 
ATOM   1593 C CB  . GLN B 2  131 ? -43.586 17.019  -51.639 1.00 17.70 ? 131  GLN H CB  1 
ATOM   1594 C CG  . GLN B 2  131 ? -43.943 18.495  -51.504 1.00 20.17 ? 131  GLN H CG  1 
ATOM   1595 C CD  . GLN B 2  131 ? -45.274 18.826  -52.154 1.00 22.87 ? 131  GLN H CD  1 
ATOM   1596 O OE1 . GLN B 2  131 ? -46.311 18.288  -51.766 1.00 24.52 ? 131  GLN H OE1 1 
ATOM   1597 N NE2 . GLN B 2  131 ? -45.251 19.711  -53.141 1.00 19.85 ? 131  GLN H NE2 1 
ATOM   1598 N N   . ALA B 2  132 ? -42.837 14.153  -50.306 1.00 16.99 ? 132  ALA H N   1 
ATOM   1599 C CA  . ALA B 2  132 ? -42.540 12.743  -50.523 1.00 16.83 ? 132  ALA H CA  1 
ATOM   1600 C C   . ALA B 2  132 ? -42.483 12.420  -52.012 1.00 16.62 ? 132  ALA H C   1 
ATOM   1601 O O   . ALA B 2  132 ? -43.367 12.816  -52.778 1.00 16.62 ? 132  ALA H O   1 
ATOM   1602 C CB  . ALA B 2  132 ? -43.598 11.889  -49.845 1.00 15.54 ? 132  ALA H CB  1 
ATOM   1603 N N   . GLY B 2  133 ? -41.442 11.697  -52.423 1.00 14.38 ? 133  GLY H N   1 
ATOM   1604 C CA  . GLY B 2  133 ? -41.311 11.338  -53.822 1.00 17.09 ? 133  GLY H CA  1 
ATOM   1605 C C   . GLY B 2  133 ? -40.369 12.240  -54.593 1.00 15.54 ? 133  GLY H C   1 
ATOM   1606 O O   . GLY B 2  133 ? -39.705 11.793  -55.524 1.00 19.04 ? 133  GLY H O   1 
ATOM   1607 N N   . TYR B 2  134 ? -40.306 13.514  -54.219 1.00 13.64 ? 134  TYR H N   1 
ATOM   1608 C CA  . TYR B 2  134 ? -39.412 14.435  -54.904 1.00 11.83 ? 134  TYR H CA  1 
ATOM   1609 C C   . TYR B 2  134 ? -37.992 14.118  -54.465 1.00 10.51 ? 134  TYR H C   1 
ATOM   1610 O O   . TYR B 2  134 ? -37.756 13.763  -53.304 1.00 10.61 ? 134  TYR H O   1 
ATOM   1611 C CB  . TYR B 2  134 ? -39.740 15.894  -54.549 1.00 12.98 ? 134  TYR H CB  1 
ATOM   1612 C CG  . TYR B 2  134 ? -41.053 16.402  -55.105 1.00 14.43 ? 134  TYR H CG  1 
ATOM   1613 C CD1 . TYR B 2  134 ? -41.905 15.565  -55.825 1.00 17.12 ? 134  TYR H CD1 1 
ATOM   1614 C CD2 . TYR B 2  134 ? -41.440 17.729  -54.916 1.00 17.58 ? 134  TYR H CD2 1 
ATOM   1615 C CE1 . TYR B 2  134 ? -43.108 16.031  -56.343 1.00 18.29 ? 134  TYR H CE1 1 
ATOM   1616 C CE2 . TYR B 2  134 ? -42.645 18.209  -55.434 1.00 20.98 ? 134  TYR H CE2 1 
ATOM   1617 C CZ  . TYR B 2  134 ? -43.473 17.351  -56.145 1.00 21.83 ? 134  TYR H CZ  1 
ATOM   1618 O OH  . TYR B 2  134 ? -44.668 17.811  -56.649 1.00 22.83 ? 134  TYR H OH  1 
ATOM   1619 N N   . LYS B 2  135 ? -37.052 14.255  -55.392 1.00 11.90 ? 135  LYS H N   1 
ATOM   1620 C CA  . LYS B 2  135 ? -35.662 13.969  -55.089 1.00 12.20 ? 135  LYS H CA  1 
ATOM   1621 C C   . LYS B 2  135 ? -34.827 15.201  -54.803 1.00 11.63 ? 135  LYS H C   1 
ATOM   1622 O O   . LYS B 2  135 ? -34.981 16.245  -55.451 1.00 12.31 ? 135  LYS H O   1 
ATOM   1623 C CB  . LYS B 2  135 ? -35.006 13.204  -56.241 1.00 13.48 ? 135  LYS H CB  1 
ATOM   1624 C CG  . LYS B 2  135 ? -35.527 11.784  -56.414 1.00 13.87 ? 135  LYS H CG  1 
ATOM   1625 C CD  . LYS B 2  135 ? -34.952 11.156  -57.670 1.00 14.61 ? 135  LYS H CD  1 
ATOM   1626 C CE  . LYS B 2  135 ? -35.478 9.736   -57.858 1.00 15.61 ? 135  LYS H CE  1 
ATOM   1627 N NZ  . LYS B 2  135 ? -34.986 9.139   -59.135 1.00 16.21 ? 135  LYS H NZ  1 
ATOM   1628 N N   . GLY B 2  136 ? -33.945 15.041  -53.824 1.00 12.31 ? 136  GLY H N   1 
ATOM   1629 C CA  . GLY B 2  136 ? -33.013 16.078  -53.437 1.00 13.14 ? 136  GLY H CA  1 
ATOM   1630 C C   . GLY B 2  136 ? -31.641 15.470  -53.664 1.00 14.62 ? 136  GLY H C   1 
ATOM   1631 O O   . GLY B 2  136 ? -31.535 14.316  -54.097 1.00 13.09 ? 136  GLY H O   1 
ATOM   1632 N N   . ARG B 2  137 ? -30.598 16.222  -53.344 1.00 13.66 ? 137  ARG H N   1 
ATOM   1633 C CA  . ARG B 2  137 ? -29.229 15.780  -53.566 1.00 12.02 ? 137  ARG H CA  1 
ATOM   1634 C C   . ARG B 2  137 ? -28.363 15.952  -52.329 1.00 12.79 ? 137  ARG H C   1 
ATOM   1635 O O   . ARG B 2  137 ? -28.406 16.993  -51.670 1.00 13.26 ? 137  ARG H O   1 
ATOM   1636 C CB  . ARG B 2  137 ? -28.644 16.581  -54.732 1.00 11.27 ? 137  ARG H CB  1 
ATOM   1637 C CG  . ARG B 2  137 ? -27.165 16.374  -54.980 1.00 11.79 ? 137  ARG H CG  1 
ATOM   1638 C CD  . ARG B 2  137 ? -26.699 17.217  -56.160 1.00 14.17 ? 137  ARG H CD  1 
ATOM   1639 N NE  . ARG B 2  137 ? -27.249 16.769  -57.438 1.00 13.67 ? 137  ARG H NE  1 
ATOM   1640 C CZ  . ARG B 2  137 ? -27.102 17.433  -58.583 1.00 14.03 ? 137  ARG H CZ  1 
ATOM   1641 N NH1 . ARG B 2  137 ? -26.425 18.581  -58.601 1.00 13.30 ? 137  ARG H NH1 1 
ATOM   1642 N NH2 . ARG B 2  137 ? -27.605 16.946  -59.710 1.00 13.80 ? 137  ARG H NH2 1 
ATOM   1643 N N   . VAL B 2  138 ? -27.569 14.930  -52.023 1.00 8.99  ? 138  VAL H N   1 
ATOM   1644 C CA  . VAL B 2  138 ? -26.674 14.967  -50.877 1.00 9.78  ? 138  VAL H CA  1 
ATOM   1645 C C   . VAL B 2  138 ? -25.242 14.825  -51.375 1.00 13.03 ? 138  VAL H C   1 
ATOM   1646 O O   . VAL B 2  138 ? -24.965 14.054  -52.293 1.00 12.89 ? 138  VAL H O   1 
ATOM   1647 C CB  . VAL B 2  138 ? -26.982 13.833  -49.875 1.00 10.61 ? 138  VAL H CB  1 
ATOM   1648 C CG1 . VAL B 2  138 ? -26.103 13.969  -48.645 1.00 12.14 ? 138  VAL H CG1 1 
ATOM   1649 C CG2 . VAL B 2  138 ? -28.457 13.877  -49.485 1.00 14.32 ? 138  VAL H CG2 1 
ATOM   1650 N N   . THR B 2  139 ? -24.341 15.590  -50.777 1.00 10.98 ? 139  THR H N   1 
ATOM   1651 C CA  . THR B 2  139 ? -22.933 15.577  -51.170 1.00 11.76 ? 139  THR H CA  1 
ATOM   1652 C C   . THR B 2  139 ? -22.034 15.454  -49.952 1.00 12.06 ? 139  THR H C   1 
ATOM   1653 O O   . THR B 2  139 ? -22.396 15.890  -48.860 1.00 13.01 ? 139  THR H O   1 
ATOM   1654 C CB  . THR B 2  139 ? -22.574 16.876  -51.883 1.00 12.64 ? 139  THR H CB  1 
ATOM   1655 O OG1 . THR B 2  139 ? -23.177 17.971  -51.183 1.00 13.29 ? 139  THR H OG1 1 
ATOM   1656 C CG2 . THR B 2  139 ? -23.048 16.856  -53.314 1.00 11.65 ? 139  THR H CG2 1 
ATOM   1657 N N   . GLY B 2  140 ? -20.854 14.869  -50.139 1.00 13.12 ? 140  GLY H N   1 
ATOM   1658 C CA  . GLY B 2  140 ? -19.934 14.732  -49.034 1.00 11.01 ? 140  GLY H CA  1 
ATOM   1659 C C   . GLY B 2  140 ? -18.712 13.897  -49.354 1.00 12.92 ? 140  GLY H C   1 
ATOM   1660 O O   . GLY B 2  140 ? -18.644 13.254  -50.405 1.00 14.70 ? 140  GLY H O   1 
ATOM   1661 N N   . TRP B 2  141 ? -17.759 13.912  -48.429 1.00 15.01 ? 141  TRP H N   1 
ATOM   1662 C CA  . TRP B 2  141 ? -16.514 13.171  -48.563 1.00 16.75 ? 141  TRP H CA  1 
ATOM   1663 C C   . TRP B 2  141 ? -16.483 12.056  -47.522 1.00 17.48 ? 141  TRP H C   1 
ATOM   1664 O O   . TRP B 2  141 ? -15.410 11.579  -47.151 1.00 17.60 ? 141  TRP H O   1 
ATOM   1665 C CB  . TRP B 2  141 ? -15.319 14.110  -48.344 1.00 17.89 ? 141  TRP H CB  1 
ATOM   1666 C CG  . TRP B 2  141 ? -15.014 15.039  -49.496 1.00 16.30 ? 141  TRP H CG  1 
ATOM   1667 C CD1 . TRP B 2  141 ? -14.316 14.742  -50.639 1.00 17.95 ? 141  TRP H CD1 1 
ATOM   1668 C CD2 . TRP B 2  141 ? -15.352 16.427  -49.586 1.00 17.11 ? 141  TRP H CD2 1 
ATOM   1669 N NE1 . TRP B 2  141 ? -14.193 15.864  -51.426 1.00 17.16 ? 141  TRP H NE1 1 
ATOM   1670 C CE2 . TRP B 2  141 ? -14.821 16.911  -50.804 1.00 17.70 ? 141  TRP H CE2 1 
ATOM   1671 C CE3 . TRP B 2  141 ? -16.053 17.310  -48.755 1.00 17.66 ? 141  TRP H CE3 1 
ATOM   1672 C CZ2 . TRP B 2  141 ? -14.969 18.240  -51.208 1.00 19.68 ? 141  TRP H CZ2 1 
ATOM   1673 C CZ3 . TRP B 2  141 ? -16.199 18.633  -49.160 1.00 16.10 ? 141  TRP H CZ3 1 
ATOM   1674 C CH2 . TRP B 2  141 ? -15.659 19.083  -50.374 1.00 17.16 ? 141  TRP H CH2 1 
ATOM   1675 N N   . GLY B 2  142 ? -17.662 11.652  -47.050 1.00 16.38 ? 142  GLY H N   1 
ATOM   1676 C CA  . GLY B 2  142 ? -17.753 10.601  -46.051 1.00 15.55 ? 142  GLY H CA  1 
ATOM   1677 C C   . GLY B 2  142 ? -17.506 9.233   -46.657 1.00 16.99 ? 142  GLY H C   1 
ATOM   1678 O O   . GLY B 2  142 ? -17.294 9.117   -47.856 1.00 15.88 ? 142  GLY H O   1 
ATOM   1679 N N   . ASN B 2  143 ? -17.555 8.195   -45.827 1.00 18.17 ? 143  ASN H N   1 
ATOM   1680 C CA  . ASN B 2  143 ? -17.307 6.832   -46.291 1.00 18.97 ? 143  ASN H CA  1 
ATOM   1681 C C   . ASN B 2  143 ? -18.258 6.321   -47.369 1.00 19.50 ? 143  ASN H C   1 
ATOM   1682 O O   . ASN B 2  143 ? -19.429 6.708   -47.434 1.00 16.94 ? 143  ASN H O   1 
ATOM   1683 C CB  . ASN B 2  143 ? -17.292 5.883   -45.089 1.00 22.19 ? 143  ASN H CB  1 
ATOM   1684 C CG  . ASN B 2  143 ? -16.239 6.272   -44.071 1.00 22.68 ? 143  ASN H CG  1 
ATOM   1685 O OD1 . ASN B 2  143 ? -15.297 7.006   -44.393 1.00 26.49 ? 143  ASN H OD1 1 
ATOM   1686 N ND2 . ASN B 2  143 ? -16.382 5.786   -42.845 1.00 25.67 ? 143  ASN H ND2 1 
ATOM   1687 N N   . LEU B 2  144 ? -17.732 5.439   -48.216 1.00 18.48 ? 144  LEU H N   1 
ATOM   1688 C CA  . LEU B 2  144 ? -18.481 4.856   -49.323 1.00 18.33 ? 144  LEU H CA  1 
ATOM   1689 C C   . LEU B 2  144 ? -19.336 3.665   -48.905 1.00 19.39 ? 144  LEU H C   1 
ATOM   1690 O O   . LEU B 2  144 ? -20.211 3.232   -49.649 1.00 20.23 ? 144  LEU H O   1 
ATOM   1691 C CB  . LEU B 2  144 ? -17.508 4.416   -50.419 1.00 19.36 ? 144  LEU H CB  1 
ATOM   1692 C CG  . LEU B 2  144 ? -16.640 5.536   -50.997 1.00 20.01 ? 144  LEU H CG  1 
ATOM   1693 C CD1 . LEU B 2  144 ? -15.614 4.944   -51.960 1.00 21.33 ? 144  LEU H CD1 1 
ATOM   1694 C CD2 . LEU B 2  144 ? -17.528 6.549   -51.702 1.00 19.97 ? 144  LEU H CD2 1 
ATOM   1695 N N   . LYS B 2  145 ? -19.066 3.132   -47.722 1.00 20.53 ? 145  LYS H N   1 
ATOM   1696 C CA  . LYS B 2  145 ? -19.816 1.991   -47.207 1.00 23.23 ? 145  LYS H CA  1 
ATOM   1697 C C   . LYS B 2  145 ? -19.834 2.042   -45.687 1.00 23.03 ? 145  LYS H C   1 
ATOM   1698 O O   . LYS B 2  145 ? -18.947 2.628   -45.067 1.00 22.62 ? 145  LYS H O   1 
ATOM   1699 C CB  . LYS B 2  145 ? -19.170 0.676   -47.662 1.00 24.78 ? 145  LYS H CB  1 
ATOM   1700 C CG  . LYS B 2  145 ? -19.149 0.459   -49.168 1.00 27.96 ? 145  LYS H CG  1 
ATOM   1701 N N   . GLU B 2  146 ? -20.840 1.414   -45.088 1.00 24.13 ? 146  GLU H N   1 
ATOM   1702 C CA  . GLU B 2  146 ? -20.955 1.391   -43.637 1.00 26.52 ? 146  GLU H CA  1 
ATOM   1703 C C   . GLU B 2  146 ? -19.762 0.680   -43.004 1.00 29.11 ? 146  GLU H C   1 
ATOM   1704 O O   . GLU B 2  146 ? -19.255 1.105   -41.968 1.00 30.80 ? 146  GLU H O   1 
ATOM   1705 C CB  . GLU B 2  146 ? -22.241 0.678   -43.217 1.00 24.53 ? 146  GLU H CB  1 
ATOM   1706 C CG  . GLU B 2  146 ? -22.506 0.735   -41.725 1.00 26.00 ? 146  GLU H CG  1 
ATOM   1707 C CD  . GLU B 2  146 ? -23.675 -0.134  -41.305 1.00 24.00 ? 146  GLU H CD  1 
ATOM   1708 O OE1 . GLU B 2  146 ? -24.727 -0.092  -41.980 1.00 23.49 ? 146  GLU H OE1 1 
ATOM   1709 O OE2 . GLU B 2  146 ? -23.541 -0.854  -40.292 1.00 29.57 ? 146  GLU H OE2 1 
ATOM   1710 N N   . THR B 2  147 ? -19.324 -0.409  -43.627 1.00 31.74 ? 147  THR H N   1 
ATOM   1711 C CA  . THR B 2  147 ? -18.196 -1.177  -43.111 1.00 35.74 ? 147  THR H CA  1 
ATOM   1712 C C   . THR B 2  147 ? -17.323 -1.731  -44.235 1.00 37.12 ? 147  THR H C   1 
ATOM   1713 O O   . THR B 2  147 ? -17.767 -1.865  -45.378 1.00 39.20 ? 147  THR H O   1 
ATOM   1714 C CB  . THR B 2  147 ? -18.680 -2.355  -42.237 1.00 36.82 ? 147  THR H CB  1 
ATOM   1715 O OG1 . THR B 2  147 ? -19.579 -3.177  -42.993 1.00 39.45 ? 147  THR H OG1 1 
ATOM   1716 C CG2 . THR B 2  147 ? -19.397 -1.839  -40.997 1.00 37.18 ? 147  THR H CG2 1 
ATOM   1717 N N   A LYS B 2  154 ? -15.812 0.604   -49.969 0.54 36.08 ? 149  LYS H N   1 
ATOM   1718 N N   B LYS B 2  154 ? -9.752  2.433   -46.109 0.46 39.70 ? 149  LYS H N   1 
ATOM   1719 C CA  A LYS B 2  154 ? -14.675 0.895   -50.832 0.50 36.17 ? 149  LYS H CA  1 
ATOM   1720 C CA  B LYS B 2  154 ? -10.872 2.629   -45.195 0.50 39.24 ? 149  LYS H CA  1 
ATOM   1721 C C   A LYS B 2  154 ? -13.688 1.814   -50.120 0.50 36.06 ? 149  LYS H C   1 
ATOM   1722 C C   B LYS B 2  154 ? -12.152 2.945   -45.960 0.50 38.76 ? 149  LYS H C   1 
ATOM   1723 O O   A LYS B 2  154 ? -12.630 2.140   -50.657 0.50 36.52 ? 149  LYS H O   1 
ATOM   1724 O O   B LYS B 2  154 ? -13.175 3.284   -45.363 0.50 39.07 ? 149  LYS H O   1 
ATOM   1725 C CB  A LYS B 2  154 ? -15.152 1.554   -52.129 0.34 36.27 ? 149  LYS H CB  1 
ATOM   1726 C CB  B LYS B 2  154 ? -10.564 3.767   -44.219 0.63 39.99 ? 149  LYS H CB  1 
ATOM   1727 N N   A GLY B 2  155 ? -14.047 2.225   -48.908 0.39 35.73 ? 150  GLY H N   1 
ATOM   1728 N N   B GLY B 2  155 ? -12.086 2.837   -47.283 0.61 37.76 ? 150  GLY H N   1 
ATOM   1729 C CA  A GLY B 2  155 ? -13.185 3.098   -48.132 0.19 35.25 ? 150  GLY H CA  1 
ATOM   1730 C CA  B GLY B 2  155 ? -13.249 3.108   -48.107 0.81 36.52 ? 150  GLY H CA  1 
ATOM   1731 C C   A GLY B 2  155 ? -13.608 4.553   -48.189 0.10 34.83 ? 150  GLY H C   1 
ATOM   1732 C C   B GLY B 2  155 ? -13.621 4.576   -48.161 0.40 35.46 ? 150  GLY H C   1 
ATOM   1733 O O   A GLY B 2  155 ? -14.767 4.886   -47.939 0.19 34.77 ? 150  GLY H O   1 
ATOM   1734 O O   B GLY B 2  155 ? -14.763 4.945   -47.881 0.81 34.86 ? 150  GLY H O   1 
ATOM   1735 N N   . GLN B 2  156 ? -12.658 5.421   -48.516 1.00 34.90 ? 151  GLN H N   1 
ATOM   1736 C CA  . GLN B 2  156 ? -12.913 6.854   -48.612 1.00 33.45 ? 151  GLN H CA  1 
ATOM   1737 C C   . GLN B 2  156 ? -12.761 7.273   -50.071 1.00 31.18 ? 151  GLN H C   1 
ATOM   1738 O O   . GLN B 2  156 ? -11.915 6.745   -50.791 1.00 32.29 ? 151  GLN H O   1 
ATOM   1739 C CB  . GLN B 2  156 ? -11.933 7.625   -47.729 1.00 35.54 ? 151  GLN H CB  1 
ATOM   1740 C CG  . GLN B 2  156 ? -11.913 7.145   -46.287 1.00 37.83 ? 151  GLN H CG  1 
ATOM   1741 C CD  . GLN B 2  156 ? -11.055 8.015   -45.394 1.00 41.06 ? 151  GLN H CD  1 
ATOM   1742 O OE1 . GLN B 2  156 ? -11.408 9.158   -45.093 1.00 43.71 ? 151  GLN H OE1 1 
ATOM   1743 N NE2 . GLN B 2  156 ? -9.914  7.483   -44.971 1.00 42.46 ? 151  GLN H NE2 1 
ATOM   1744 N N   . PRO B 2  157 ? -13.587 8.225   -50.529 1.00 27.19 ? 152  PRO H N   1 
ATOM   1745 C CA  . PRO B 2  157 ? -13.554 8.716   -51.908 1.00 24.96 ? 152  PRO H CA  1 
ATOM   1746 C C   . PRO B 2  157 ? -12.380 9.641   -52.233 1.00 23.68 ? 152  PRO H C   1 
ATOM   1747 O O   . PRO B 2  157 ? -11.869 10.338  -51.363 1.00 23.95 ? 152  PRO H O   1 
ATOM   1748 C CB  . PRO B 2  157 ? -14.894 9.431   -52.037 1.00 23.48 ? 152  PRO H CB  1 
ATOM   1749 C CG  . PRO B 2  157 ? -15.060 10.022  -50.670 1.00 23.72 ? 152  PRO H CG  1 
ATOM   1750 C CD  . PRO B 2  157 ? -14.681 8.866   -49.774 1.00 24.60 ? 152  PRO H CD  1 
ATOM   1751 N N   A SER B 2  158 ? -11.963 9.638   -53.494 0.18 22.93 ? 153  SER H N   1 
ATOM   1752 N N   B SER B 2  158 ? -11.959 9.641   -53.493 0.65 22.84 ? 153  SER H N   1 
ATOM   1753 C CA  A SER B 2  158 ? -10.864 10.485  -53.935 0.14 22.00 ? 153  SER H CA  1 
ATOM   1754 C CA  B SER B 2  158 ? -10.857 10.492  -53.921 0.47 22.05 ? 153  SER H CA  1 
ATOM   1755 C C   A SER B 2  158 ? -11.365 11.912  -54.115 0.10 20.98 ? 153  SER H C   1 
ATOM   1756 C C   B SER B 2  158 ? -11.366 11.918  -54.112 0.70 20.95 ? 153  SER H C   1 
ATOM   1757 O O   A SER B 2  158 ? -10.635 12.875  -53.882 0.16 20.97 ? 153  SER H O   1 
ATOM   1758 O O   B SER B 2  158 ? -10.644 12.886  -53.879 0.54 21.30 ? 153  SER H O   1 
ATOM   1759 C CB  A SER B 2  158 ? -10.294 9.972   -55.258 0.15 22.52 ? 153  SER H CB  1 
ATOM   1760 C CB  B SER B 2  158 ? -10.263 9.971   -55.232 0.28 22.57 ? 153  SER H CB  1 
ATOM   1761 O OG  A SER B 2  158 ? -9.305  10.855  -55.759 0.37 23.37 ? 153  SER H OG  1 
ATOM   1762 O OG  B SER B 2  158 ? -11.245 9.918   -56.251 0.40 22.81 ? 153  SER H OG  1 
ATOM   1763 N N   . VAL B 2  159 ? -12.621 12.038  -54.532 1.00 19.61 ? 154  VAL H N   1 
ATOM   1764 C CA  . VAL B 2  159 ? -13.228 13.345  -54.751 1.00 18.80 ? 154  VAL H CA  1 
ATOM   1765 C C   . VAL B 2  159 ? -14.645 13.388  -54.196 1.00 16.60 ? 154  VAL H C   1 
ATOM   1766 O O   . VAL B 2  159 ? -15.237 12.351  -53.884 1.00 14.61 ? 154  VAL H O   1 
ATOM   1767 C CB  . VAL B 2  159 ? -13.280 13.703  -56.249 1.00 18.98 ? 154  VAL H CB  1 
ATOM   1768 C CG1 . VAL B 2  159 ? -11.882 13.590  -56.857 1.00 19.55 ? 154  VAL H CG1 1 
ATOM   1769 C CG2 . VAL B 2  159 ? -14.250 12.796  -56.976 1.00 21.53 ? 154  VAL H CG2 1 
ATOM   1770 N N   . LEU B 2  160 ? -15.173 14.602  -54.075 1.00 14.26 ? 155  LEU H N   1 
ATOM   1771 C CA  . LEU B 2  160 ? -16.521 14.822  -53.562 1.00 14.47 ? 155  LEU H CA  1 
ATOM   1772 C C   . LEU B 2  160 ? -17.536 13.893  -54.215 1.00 13.20 ? 155  LEU H C   1 
ATOM   1773 O O   . LEU B 2  160 ? -17.592 13.784  -55.442 1.00 14.37 ? 155  LEU H O   1 
ATOM   1774 C CB  . LEU B 2  160 ? -16.930 16.277  -53.810 1.00 12.31 ? 155  LEU H CB  1 
ATOM   1775 C CG  . LEU B 2  160 ? -18.316 16.685  -53.305 1.00 14.82 ? 155  LEU H CG  1 
ATOM   1776 C CD1 . LEU B 2  160 ? -18.339 16.645  -51.794 1.00 11.51 ? 155  LEU H CD1 1 
ATOM   1777 C CD2 . LEU B 2  160 ? -18.646 18.080  -53.804 1.00 16.35 ? 155  LEU H CD2 1 
ATOM   1778 N N   . GLN B 2  161 ? -18.357 13.247  -53.389 1.00 14.76 ? 156  GLN H N   1 
ATOM   1779 C CA  . GLN B 2  161 ? -19.378 12.338  -53.889 1.00 15.36 ? 156  GLN H CA  1 
ATOM   1780 C C   . GLN B 2  161 ? -20.757 12.986  -53.881 1.00 15.31 ? 156  GLN H C   1 
ATOM   1781 O O   . GLN B 2  161 ? -21.045 13.861  -53.053 1.00 14.83 ? 156  GLN H O   1 
ATOM   1782 C CB  . GLN B 2  161 ? -19.411 11.059  -53.049 1.00 14.99 ? 156  GLN H CB  1 
ATOM   1783 C CG  . GLN B 2  161 ? -18.133 10.231  -53.153 1.00 17.02 ? 156  GLN H CG  1 
ATOM   1784 C CD  . GLN B 2  161 ? -17.916 9.696   -54.552 1.00 18.88 ? 156  GLN H CD  1 
ATOM   1785 O OE1 . GLN B 2  161 ? -18.656 8.824   -55.015 1.00 19.51 ? 156  GLN H OE1 1 
ATOM   1786 N NE2 . GLN B 2  161 ? -16.906 10.222  -55.241 1.00 16.74 ? 156  GLN H NE2 1 
ATOM   1787 N N   A VAL B 2  162 ? -21.608 12.540  -54.798 0.13 14.31 ? 157  VAL H N   1 
ATOM   1788 N N   B VAL B 2  162 ? -21.603 12.552  -54.808 0.87 14.59 ? 157  VAL H N   1 
ATOM   1789 C CA  A VAL B 2  162 ? -22.961 13.064  -54.917 0.20 13.59 ? 157  VAL H CA  1 
ATOM   1790 C CA  B VAL B 2  162 ? -22.960 13.075  -54.927 0.80 14.69 ? 157  VAL H CA  1 
ATOM   1791 C C   A VAL B 2  162 ? -23.964 11.937  -55.121 0.32 13.20 ? 157  VAL H C   1 
ATOM   1792 C C   B VAL B 2  162 ? -23.970 11.951  -55.141 0.58 14.03 ? 157  VAL H C   1 
ATOM   1793 O O   A VAL B 2  162 ? -23.678 10.952  -55.795 0.37 11.09 ? 157  VAL H O   1 
ATOM   1794 O O   B VAL B 2  162 ? -23.692 10.981  -55.841 0.32 12.24 ? 157  VAL H O   1 
ATOM   1795 C CB  A VAL B 2  162 ? -23.078 14.027  -56.119 0.37 13.89 ? 157  VAL H CB  1 
ATOM   1796 C CB  B VAL B 2  162 ? -23.061 14.070  -56.112 0.63 15.69 ? 157  VAL H CB  1 
ATOM   1797 C CG1 A VAL B 2  162 ? -24.481 14.603  -56.192 0.11 14.00 ? 157  VAL H CG1 1 
ATOM   1798 C CG1 B VAL B 2  162 ? -22.710 13.371  -57.414 0.72 17.00 ? 157  VAL H CG1 1 
ATOM   1799 C CG2 A VAL B 2  162 ? -22.053 15.136  -55.998 0.24 13.80 ? 157  VAL H CG2 1 
ATOM   1800 C CG2 B VAL B 2  162 ? -24.458 14.657  -56.185 0.76 16.70 ? 157  VAL H CG2 1 
ATOM   1801 N N   . VAL B 2  163 ? -25.143 12.081  -54.525 1.00 12.96 ? 158  VAL H N   1 
ATOM   1802 C CA  . VAL B 2  163 ? -26.185 11.087  -54.687 1.00 14.07 ? 158  VAL H CA  1 
ATOM   1803 C C   . VAL B 2  163 ? -27.535 11.793  -54.615 1.00 15.50 ? 158  VAL H C   1 
ATOM   1804 O O   . VAL B 2  163 ? -27.718 12.716  -53.813 1.00 14.04 ? 158  VAL H O   1 
ATOM   1805 C CB  . VAL B 2  163 ? -26.089 9.967   -53.615 1.00 14.01 ? 158  VAL H CB  1 
ATOM   1806 C CG1 . VAL B 2  163 ? -26.398 10.512  -52.231 1.00 15.47 ? 158  VAL H CG1 1 
ATOM   1807 C CG2 . VAL B 2  163 ? -27.027 8.831   -53.981 1.00 15.79 ? 158  VAL H CG2 1 
ATOM   1808 N N   . ASN B 2  164 ? -28.450 11.397  -55.497 1.00 13.68 ? 159  ASN H N   1 
ATOM   1809 C CA  . ASN B 2  164 ? -29.798 11.974  -55.516 1.00 12.61 ? 159  ASN H CA  1 
ATOM   1810 C C   . ASN B 2  164 ? -30.707 10.989  -54.796 1.00 14.10 ? 159  ASN H C   1 
ATOM   1811 O O   . ASN B 2  164 ? -30.679 9.785   -55.084 1.00 13.88 ? 159  ASN H O   1 
ATOM   1812 C CB  . ASN B 2  164 ? -30.271 12.204  -56.954 1.00 13.53 ? 159  ASN H CB  1 
ATOM   1813 C CG  . ASN B 2  164 ? -29.436 13.242  -57.674 1.00 17.25 ? 159  ASN H CG  1 
ATOM   1814 O OD1 . ASN B 2  164 ? -28.818 14.099  -57.039 1.00 14.44 ? 159  ASN H OD1 1 
ATOM   1815 N ND2 . ASN B 2  164 ? -29.424 13.185  -59.003 1.00 19.31 ? 159  ASN H ND2 1 
ATOM   1816 N N   . LEU B 2  165 ? -31.511 11.493  -53.862 1.00 11.86 ? 160  LEU H N   1 
ATOM   1817 C CA  . LEU B 2  165 ? -32.390 10.632  -53.068 1.00 13.01 ? 160  LEU H CA  1 
ATOM   1818 C C   . LEU B 2  165 ? -33.792 11.196  -52.919 1.00 13.39 ? 160  LEU H C   1 
ATOM   1819 O O   . LEU B 2  165 ? -33.970 12.407  -52.802 1.00 13.19 ? 160  LEU H O   1 
ATOM   1820 C CB  . LEU B 2  165 ? -31.795 10.439  -51.672 1.00 12.11 ? 160  LEU H CB  1 
ATOM   1821 C CG  . LEU B 2  165 ? -30.369 9.887   -51.557 1.00 13.27 ? 160  LEU H CG  1 
ATOM   1822 C CD1 . LEU B 2  165 ? -29.895 9.940   -50.110 1.00 14.50 ? 160  LEU H CD1 1 
ATOM   1823 C CD2 . LEU B 2  165 ? -30.351 8.459   -52.088 1.00 13.98 ? 160  LEU H CD2 1 
ATOM   1824 N N   . PRO B 2  166 ? -34.810 10.323  -52.916 1.00 12.44 ? 161  PRO H N   1 
ATOM   1825 C CA  . PRO B 2  166 ? -36.191 10.789  -52.772 1.00 12.63 ? 161  PRO H CA  1 
ATOM   1826 C C   . PRO B 2  166 ? -36.587 11.013  -51.320 1.00 12.54 ? 161  PRO H C   1 
ATOM   1827 O O   . PRO B 2  166 ? -36.176 10.269  -50.423 1.00 11.68 ? 161  PRO H O   1 
ATOM   1828 C CB  . PRO B 2  166 ? -37.001 9.659   -53.402 1.00 14.65 ? 161  PRO H CB  1 
ATOM   1829 C CG  . PRO B 2  166 ? -36.212 8.460   -53.000 1.00 13.31 ? 161  PRO H CG  1 
ATOM   1830 C CD  . PRO B 2  166 ? -34.779 8.880   -53.244 1.00 13.65 ? 161  PRO H CD  1 
ATOM   1831 N N   . ILE B 2  167 ? -37.387 12.052  -51.093 1.00 11.39 ? 162  ILE H N   1 
ATOM   1832 C CA  . ILE B 2  167 ? -37.894 12.356  -49.770 1.00 12.88 ? 162  ILE H CA  1 
ATOM   1833 C C   . ILE B 2  167 ? -38.944 11.283  -49.472 1.00 12.43 ? 162  ILE H C   1 
ATOM   1834 O O   . ILE B 2  167 ? -39.688 10.868  -50.365 1.00 13.33 ? 162  ILE H O   1 
ATOM   1835 C CB  . ILE B 2  167 ? -38.530 13.759  -49.757 1.00 13.56 ? 162  ILE H CB  1 
ATOM   1836 C CG1 . ILE B 2  167 ? -37.433 14.799  -50.011 1.00 14.29 ? 162  ILE H CG1 1 
ATOM   1837 C CG2 . ILE B 2  167 ? -39.232 14.014  -48.425 1.00 14.93 ? 162  ILE H CG2 1 
ATOM   1838 C CD1 . ILE B 2  167 ? -37.949 16.165  -50.369 1.00 15.57 ? 162  ILE H CD1 1 
ATOM   1839 N N   . VAL B 2  168 ? -38.986 10.835  -48.223 1.00 14.15 ? 163  VAL H N   1 
ATOM   1840 C CA  . VAL B 2  168 ? -39.898 9.782   -47.796 1.00 14.02 ? 163  VAL H CA  1 
ATOM   1841 C C   . VAL B 2  168 ? -41.031 10.326  -46.930 1.00 14.90 ? 163  VAL H C   1 
ATOM   1842 O O   . VAL B 2  168 ? -40.831 11.269  -46.162 1.00 13.04 ? 163  VAL H O   1 
ATOM   1843 C CB  . VAL B 2  168 ? -39.102 8.701   -47.015 1.00 13.75 ? 163  VAL H CB  1 
ATOM   1844 C CG1 . VAL B 2  168 ? -40.026 7.594   -46.506 1.00 15.39 ? 163  VAL H CG1 1 
ATOM   1845 C CG2 . VAL B 2  168 ? -38.028 8.110   -47.933 1.00 14.94 ? 163  VAL H CG2 1 
ATOM   1846 N N   . GLU B 2  169 ? -42.218 9.744   -47.081 1.00 14.58 ? 164  GLU H N   1 
ATOM   1847 C CA  . GLU B 2  169 ? -43.389 10.143  -46.302 1.00 18.04 ? 164  GLU H CA  1 
ATOM   1848 C C   . GLU B 2  169 ? -43.087 10.019  -44.810 1.00 16.50 ? 164  GLU H C   1 
ATOM   1849 O O   . GLU B 2  169 ? -42.466 9.051   -44.375 1.00 14.35 ? 164  GLU H O   1 
ATOM   1850 C CB  . GLU B 2  169 ? -44.594 9.258   -46.656 1.00 20.56 ? 164  GLU H CB  1 
ATOM   1851 C CG  . GLU B 2  169 ? -45.074 9.389   -48.096 1.00 24.99 ? 164  GLU H CG  1 
ATOM   1852 C CD  . GLU B 2  169 ? -44.343 8.473   -49.065 1.00 28.35 ? 164  GLU H CD  1 
ATOM   1853 O OE1 . GLU B 2  169 ? -43.272 7.932   -48.708 1.00 30.38 ? 164  GLU H OE1 1 
ATOM   1854 O OE2 . GLU B 2  169 ? -44.841 8.303   -50.200 1.00 29.92 ? 164  GLU H OE2 1 
ATOM   1855 N N   . ARG B 2  170 ? -43.539 10.987  -44.017 1.00 16.14 ? 165  ARG H N   1 
ATOM   1856 C CA  . ARG B 2  170 ? -43.275 10.960  -42.583 1.00 17.02 ? 165  ARG H CA  1 
ATOM   1857 C C   . ARG B 2  170 ? -43.691 9.658   -41.878 1.00 17.17 ? 165  ARG H C   1 
ATOM   1858 O O   . ARG B 2  170 ? -42.952 9.146   -41.045 1.00 16.26 ? 165  ARG H O   1 
ATOM   1859 C CB  . ARG B 2  170 ? -43.920 12.180  -41.905 1.00 18.52 ? 165  ARG H CB  1 
ATOM   1860 C CG  . ARG B 2  170 ? -43.485 12.390  -40.458 1.00 21.18 ? 165  ARG H CG  1 
ATOM   1861 C CD  . ARG B 2  170 ? -43.755 13.828  -40.004 1.00 24.09 ? 165  ARG H CD  1 
ATOM   1862 N NE  . ARG B 2  170 ? -42.948 14.791  -40.753 1.00 23.59 ? 165  ARG H NE  1 
ATOM   1863 C CZ  . ARG B 2  170 ? -41.690 15.114  -40.458 1.00 24.42 ? 165  ARG H CZ  1 
ATOM   1864 N NH1 . ARG B 2  170 ? -41.085 14.557  -39.416 1.00 21.86 ? 165  ARG H NH1 1 
ATOM   1865 N NH2 . ARG B 2  170 ? -41.029 15.983  -41.221 1.00 21.37 ? 165  ARG H NH2 1 
ATOM   1866 N N   . PRO B 2  171 ? -44.876 9.105   -42.201 1.00 17.47 ? 166  PRO H N   1 
ATOM   1867 C CA  . PRO B 2  171 ? -45.278 7.856   -41.536 1.00 17.67 ? 166  PRO H CA  1 
ATOM   1868 C C   . PRO B 2  171 ? -44.290 6.714   -41.791 1.00 16.22 ? 166  PRO H C   1 
ATOM   1869 O O   . PRO B 2  171 ? -44.041 5.886   -40.910 1.00 15.33 ? 166  PRO H O   1 
ATOM   1870 C CB  . PRO B 2  171 ? -46.651 7.576   -42.138 1.00 19.06 ? 166  PRO H CB  1 
ATOM   1871 C CG  . PRO B 2  171 ? -47.191 8.952   -42.364 1.00 20.22 ? 166  PRO H CG  1 
ATOM   1872 C CD  . PRO B 2  171 ? -46.001 9.674   -42.963 1.00 18.67 ? 166  PRO H CD  1 
ATOM   1873 N N   . VAL B 2  172 ? -43.732 6.671   -42.999 1.00 15.68 ? 167  VAL H N   1 
ATOM   1874 C CA  . VAL B 2  172 ? -42.766 5.631   -43.347 1.00 15.39 ? 167  VAL H CA  1 
ATOM   1875 C C   . VAL B 2  172 ? -41.460 5.878   -42.595 1.00 15.82 ? 167  VAL H C   1 
ATOM   1876 O O   . VAL B 2  172 ? -40.829 4.941   -42.105 1.00 14.27 ? 167  VAL H O   1 
ATOM   1877 C CB  . VAL B 2  172 ? -42.513 5.599   -44.868 1.00 14.61 ? 167  VAL H CB  1 
ATOM   1878 C CG1 . VAL B 2  172 ? -41.448 4.559   -45.208 1.00 17.37 ? 167  VAL H CG1 1 
ATOM   1879 C CG2 . VAL B 2  172 ? -43.809 5.273   -45.591 1.00 16.16 ? 167  VAL H CG2 1 
ATOM   1880 N N   . CYS B 2  173 ? -41.057 7.144   -42.495 1.00 14.35 ? 168  CYS H N   1 
ATOM   1881 C CA  . CYS B 2  173 ? -39.847 7.478   -41.758 1.00 13.42 ? 168  CYS H CA  1 
ATOM   1882 C C   . CYS B 2  173 ? -40.009 7.027   -40.308 1.00 12.84 ? 168  CYS H C   1 
ATOM   1883 O O   . CYS B 2  173 ? -39.098 6.452   -39.712 1.00 12.15 ? 168  CYS H O   1 
ATOM   1884 C CB  . CYS B 2  173 ? -39.602 8.994   -41.755 1.00 14.68 ? 168  CYS H CB  1 
ATOM   1885 S SG  . CYS B 2  173 ? -39.233 9.727   -43.375 1.00 15.01 ? 168  CYS H SG  1 
ATOM   1886 N N   . LYS B 2  174 ? -41.177 7.315   -39.741 1.00 13.27 ? 169  LYS H N   1 
ATOM   1887 C CA  . LYS B 2  174 ? -41.449 6.981   -38.350 1.00 14.65 ? 169  LYS H CA  1 
ATOM   1888 C C   . LYS B 2  174 ? -41.421 5.481   -38.102 1.00 13.96 ? 169  LYS H C   1 
ATOM   1889 O O   . LYS B 2  174 ? -40.837 5.018   -37.127 1.00 15.73 ? 169  LYS H O   1 
ATOM   1890 C CB  . LYS B 2  174 ? -42.809 7.539   -37.931 1.00 18.77 ? 169  LYS H CB  1 
ATOM   1891 C CG  . LYS B 2  174 ? -43.174 7.230   -36.489 1.00 24.94 ? 169  LYS H CG  1 
ATOM   1892 C CD  . LYS B 2  174 ? -44.577 7.709   -36.152 1.00 30.71 ? 169  LYS H CD  1 
ATOM   1893 C CE  . LYS B 2  174 ? -45.008 7.207   -34.783 1.00 33.22 ? 169  LYS H CE  1 
ATOM   1894 N NZ  . LYS B 2  174 ? -45.019 5.717   -34.735 1.00 36.94 ? 169  LYS H NZ  1 
ATOM   1895 N N   A ASP B 2  175 ? -42.040 4.742   -39.014 0.53 13.61 ? 170  ASP H N   1 
ATOM   1896 N N   B ASP B 2  175 ? -42.055 4.714   -38.980 0.47 14.84 ? 170  ASP H N   1 
ATOM   1897 C CA  A ASP B 2  175 ? -42.119 3.290   -38.925 0.10 13.82 ? 170  ASP H CA  1 
ATOM   1898 C CA  B ASP B 2  175 ? -42.078 3.266   -38.800 0.79 15.61 ? 170  ASP H CA  1 
ATOM   1899 C C   A ASP B 2  175 ? -40.781 2.593   -39.160 0.25 13.87 ? 170  ASP H C   1 
ATOM   1900 C C   B ASP B 2  175 ? -40.733 2.603   -39.068 0.33 14.93 ? 170  ASP H C   1 
ATOM   1901 O O   A ASP B 2  175 ? -40.627 1.414   -38.842 0.10 13.90 ? 170  ASP H O   1 
ATOM   1902 O O   B ASP B 2  175 ? -40.520 1.458   -38.680 0.73 14.32 ? 170  ASP H O   1 
ATOM   1903 C CB  A ASP B 2  175 ? -43.128 2.773   -39.946 0.69 13.21 ? 170  ASP H CB  1 
ATOM   1904 C CB  B ASP B 2  175 ? -43.151 2.630   -39.686 0.16 16.91 ? 170  ASP H CB  1 
ATOM   1905 C CG  A ASP B 2  175 ? -43.342 1.280   -39.846 0.29 13.34 ? 170  ASP H CG  1 
ATOM   1906 C CG  B ASP B 2  175 ? -44.554 2.995   -39.247 0.50 18.32 ? 170  ASP H CG  1 
ATOM   1907 O OD1 A ASP B 2  175 ? -43.928 0.830   -38.840 0.15 13.52 ? 170  ASP H OD1 1 
ATOM   1908 O OD1 B ASP B 2  175 ? -44.787 3.078   -38.022 0.35 20.08 ? 170  ASP H OD1 1 
ATOM   1909 O OD2 A ASP B 2  175 ? -42.918 0.558   -40.772 0.11 13.59 ? 170  ASP H OD2 1 
ATOM   1910 O OD2 B ASP B 2  175 ? -45.424 3.184   -40.124 0.46 19.55 ? 170  ASP H OD2 1 
ATOM   1911 N N   . SER B 2  176 ? -39.818 3.319   -39.716 1.00 14.54 ? 171  SER H N   1 
ATOM   1912 C CA  . SER B 2  176 ? -38.508 2.748   -40.016 1.00 13.75 ? 171  SER H CA  1 
ATOM   1913 C C   . SER B 2  176 ? -37.528 2.747   -38.853 1.00 14.46 ? 171  SER H C   1 
ATOM   1914 O O   . SER B 2  176 ? -36.465 2.142   -38.950 1.00 13.94 ? 171  SER H O   1 
ATOM   1915 C CB  . SER B 2  176 ? -37.857 3.502   -41.177 1.00 13.63 ? 171  SER H CB  1 
ATOM   1916 O OG  . SER B 2  176 ? -37.330 4.739   -40.714 1.00 15.58 ? 171  SER H OG  1 
ATOM   1917 N N   . THR B 2  177 ? -37.871 3.426   -37.759 1.00 15.23 ? 172  THR H N   1 
ATOM   1918 C CA  . THR B 2  177 ? -36.966 3.531   -36.620 1.00 16.02 ? 172  THR H CA  1 
ATOM   1919 C C   . THR B 2  177 ? -37.684 3.605   -35.272 1.00 15.72 ? 172  THR H C   1 
ATOM   1920 O O   . THR B 2  177 ? -38.840 4.024   -35.192 1.00 15.32 ? 172  THR H O   1 
ATOM   1921 C CB  . THR B 2  177 ? -36.096 4.801   -36.764 1.00 15.56 ? 172  THR H CB  1 
ATOM   1922 O OG1 . THR B 2  177 ? -35.188 4.905   -35.663 1.00 16.57 ? 172  THR H OG1 1 
ATOM   1923 C CG2 . THR B 2  177 ? -36.994 6.034   -36.806 1.00 16.53 ? 172  THR H CG2 1 
ATOM   1924 N N   . ARG B 2  178 ? -36.978 3.207   -34.217 1.00 17.52 ? 173  ARG H N   1 
ATOM   1925 C CA  . ARG B 2  178 ? -37.514 3.236   -32.857 1.00 19.56 ? 173  ARG H CA  1 
ATOM   1926 C C   . ARG B 2  178 ? -37.332 4.634   -32.277 1.00 19.48 ? 173  ARG H C   1 
ATOM   1927 O O   . ARG B 2  178 ? -37.955 4.994   -31.273 1.00 20.88 ? 173  ARG H O   1 
ATOM   1928 C CB  . ARG B 2  178 ? -36.769 2.231   -31.974 1.00 22.60 ? 173  ARG H CB  1 
ATOM   1929 C CG  . ARG B 2  178 ? -36.905 0.782   -32.412 1.00 28.62 ? 173  ARG H CG  1 
ATOM   1930 C CD  . ARG B 2  178 ? -35.860 -0.090  -31.727 1.00 32.73 ? 173  ARG H CD  1 
ATOM   1931 N NE  . ARG B 2  178 ? -34.509 0.191   -32.216 1.00 35.20 ? 173  ARG H NE  1 
ATOM   1932 C CZ  . ARG B 2  178 ? -33.401 -0.316  -31.685 1.00 38.84 ? 173  ARG H CZ  1 
ATOM   1933 N NH1 . ARG B 2  178 ? -33.477 -1.133  -30.641 1.00 41.12 ? 173  ARG H NH1 1 
ATOM   1934 N NH2 . ARG B 2  178 ? -32.215 -0.014  -32.198 1.00 40.62 ? 173  ARG H NH2 1 
ATOM   1935 N N   A ILE B 2  179 ? -36.470 5.415   -32.921 0.28 18.48 ? 174  ILE H N   1 
ATOM   1936 N N   B ILE B 2  179 ? -36.453 5.412   -32.898 0.72 18.28 ? 174  ILE H N   1 
ATOM   1937 C CA  A ILE B 2  179 ? -36.191 6.781   -32.493 0.10 17.62 ? 174  ILE H CA  1 
ATOM   1938 C CA  B ILE B 2  179 ? -36.186 6.770   -32.438 0.90 17.84 ? 174  ILE H CA  1 
ATOM   1939 C C   A ILE B 2  179 ? -37.412 7.667   -32.712 0.16 17.28 ? 174  ILE H C   1 
ATOM   1940 C C   B ILE B 2  179 ? -37.393 7.661   -32.703 0.82 17.96 ? 174  ILE H C   1 
ATOM   1941 O O   A ILE B 2  179 ? -38.101 7.549   -33.725 0.45 14.11 ? 174  ILE H O   1 
ATOM   1942 O O   B ILE B 2  179 ? -38.048 7.547   -33.739 0.23 16.53 ? 174  ILE H O   1 
ATOM   1943 C CB  A ILE B 2  179 ? -34.998 7.383   -33.284 0.34 17.71 ? 174  ILE H CB  1 
ATOM   1944 C CB  B ILE B 2  179 ? -34.938 7.348   -33.143 0.61 18.21 ? 174  ILE H CB  1 
ATOM   1945 C CG1 A ILE B 2  179 ? -33.718 6.605   -32.973 0.30 18.04 ? 174  ILE H CG1 1 
ATOM   1946 C CG1 B ILE B 2  179 ? -33.710 6.538   -32.727 0.48 18.80 ? 174  ILE H CG1 1 
ATOM   1947 C CG2 A ILE B 2  179 ? -34.823 8.858   -32.937 0.38 17.92 ? 174  ILE H CG2 1 
ATOM   1948 C CG2 B ILE B 2  179 ? -34.754 8.820   -32.786 0.57 18.66 ? 174  ILE H CG2 1 
ATOM   1949 C CD1 A ILE B 2  179 ? -33.325 6.624   -31.510 0.47 17.96 ? 174  ILE H CD1 1 
ATOM   1950 C CD1 B ILE B 2  179 ? -32.455 6.918   -33.445 0.39 18.56 ? 174  ILE H CD1 1 
ATOM   1951 N N   . ARG B 2  180 ? -37.683 8.548   -31.756 1.00 18.13 ? 175  ARG H N   1 
ATOM   1952 C CA  . ARG B 2  180 ? -38.811 9.460   -31.871 1.00 19.09 ? 175  ARG H CA  1 
ATOM   1953 C C   . ARG B 2  180 ? -38.452 10.526  -32.901 1.00 19.54 ? 175  ARG H C   1 
ATOM   1954 O O   . ARG B 2  180 ? -37.525 11.314  -32.693 1.00 19.82 ? 175  ARG H O   1 
ATOM   1955 C CB  . ARG B 2  180 ? -39.099 10.121  -30.518 1.00 22.41 ? 175  ARG H CB  1 
ATOM   1956 C CG  . ARG B 2  180 ? -40.290 11.078  -30.515 1.00 25.98 ? 175  ARG H CG  1 
ATOM   1957 C CD  . ARG B 2  180 ? -40.522 11.660  -29.121 1.00 29.96 ? 175  ARG H CD  1 
ATOM   1958 N NE  . ARG B 2  180 ? -39.457 12.578  -28.724 1.00 32.82 ? 175  ARG H NE  1 
ATOM   1959 C CZ  . ARG B 2  180 ? -39.422 13.871  -29.037 1.00 33.13 ? 175  ARG H CZ  1 
ATOM   1960 N NH1 . ARG B 2  180 ? -38.406 14.624  -28.638 1.00 32.89 ? 175  ARG H NH1 1 
ATOM   1961 N NH2 . ARG B 2  180 ? -40.412 14.417  -29.730 1.00 35.75 ? 175  ARG H NH2 1 
ATOM   1962 N N   . ILE B 2  181 ? -39.174 10.541  -34.016 1.00 18.84 ? 176  ILE H N   1 
ATOM   1963 C CA  . ILE B 2  181 ? -38.923 11.523  -35.069 1.00 20.70 ? 176  ILE H CA  1 
ATOM   1964 C C   . ILE B 2  181 ? -39.720 12.790  -34.780 1.00 19.95 ? 176  ILE H C   1 
ATOM   1965 O O   . ILE B 2  181 ? -40.862 12.717  -34.326 1.00 21.91 ? 176  ILE H O   1 
ATOM   1966 C CB  . ILE B 2  181 ? -39.338 10.971  -36.456 1.00 19.92 ? 176  ILE H CB  1 
ATOM   1967 C CG1 . ILE B 2  181 ? -38.655 9.621   -36.699 1.00 21.12 ? 176  ILE H CG1 1 
ATOM   1968 C CG2 . ILE B 2  181 ? -38.945 11.954  -37.560 1.00 23.95 ? 176  ILE H CG2 1 
ATOM   1969 C CD1 . ILE B 2  181 ? -37.174 9.623   -36.436 1.00 24.10 ? 176  ILE H CD1 1 
ATOM   1970 N N   . THR B 2  182 ? -39.119 13.951  -35.027 1.00 18.00 ? 177  THR H N   1 
ATOM   1971 C CA  . THR B 2  182 ? -39.800 15.222  -34.792 1.00 17.80 ? 177  THR H CA  1 
ATOM   1972 C C   . THR B 2  182 ? -40.008 15.965  -36.105 1.00 18.07 ? 177  THR H C   1 
ATOM   1973 O O   . THR B 2  182 ? -39.479 15.571  -37.144 1.00 15.43 ? 177  THR H O   1 
ATOM   1974 C CB  . THR B 2  182 ? -38.986 16.160  -33.875 1.00 17.29 ? 177  THR H CB  1 
ATOM   1975 O OG1 . THR B 2  182 ? -37.834 16.632  -34.585 1.00 15.56 ? 177  THR H OG1 1 
ATOM   1976 C CG2 . THR B 2  182 ? -38.533 15.437  -32.618 1.00 18.00 ? 177  THR H CG2 1 
ATOM   1977 N N   . ASP B 2  183 ? -40.757 17.061  -36.046 1.00 17.17 ? 178  ASP H N   1 
ATOM   1978 C CA  . ASP B 2  183 ? -41.019 17.860  -37.233 1.00 19.16 ? 178  ASP H CA  1 
ATOM   1979 C C   . ASP B 2  183 ? -39.787 18.640  -37.687 1.00 16.46 ? 178  ASP H C   1 
ATOM   1980 O O   . ASP B 2  183 ? -39.818 19.285  -38.725 1.00 18.81 ? 178  ASP H O   1 
ATOM   1981 C CB  . ASP B 2  183 ? -42.177 18.833  -36.985 1.00 23.58 ? 178  ASP H CB  1 
ATOM   1982 C CG  . ASP B 2  183 ? -43.487 18.121  -36.713 1.00 26.83 ? 178  ASP H CG  1 
ATOM   1983 O OD1 . ASP B 2  183 ? -43.695 17.019  -37.267 1.00 31.36 ? 178  ASP H OD1 1 
ATOM   1984 O OD2 . ASP B 2  183 ? -44.314 18.670  -35.960 1.00 31.69 ? 178  ASP H OD2 1 
ATOM   1985 N N   . ASN B 2  184 ? -38.707 18.584  -36.913 1.00 15.37 ? 179  ASN H N   1 
ATOM   1986 C CA  . ASN B 2  184 ? -37.479 19.288  -37.287 1.00 14.21 ? 179  ASN H CA  1 
ATOM   1987 C C   . ASN B 2  184 ? -36.571 18.346  -38.046 1.00 14.34 ? 179  ASN H C   1 
ATOM   1988 O O   . ASN B 2  184 ? -35.391 18.637  -38.250 1.00 12.75 ? 179  ASN H O   1 
ATOM   1989 C CB  . ASN B 2  184 ? -36.748 19.790  -36.053 1.00 15.51 ? 179  ASN H CB  1 
ATOM   1990 C CG  . ASN B 2  184 ? -37.589 20.732  -35.243 1.00 15.31 ? 179  ASN H CG  1 
ATOM   1991 O OD1 . ASN B 2  184 ? -38.109 21.717  -35.768 1.00 19.42 ? 179  ASN H OD1 1 
ATOM   1992 N ND2 . ASN B 2  184 ? -37.742 20.432  -33.958 1.00 16.54 ? 179  ASN H ND2 1 
ATOM   1993 N N   . MET B 2  185 ? -37.128 17.204  -38.440 1.00 12.99 ? 180  MET H N   1 
ATOM   1994 C CA  . MET B 2  185 ? -36.374 16.200  -39.182 1.00 13.69 ? 180  MET H CA  1 
ATOM   1995 C C   . MET B 2  185 ? -37.204 15.687  -40.346 1.00 13.72 ? 180  MET H C   1 
ATOM   1996 O O   . MET B 2  185 ? -38.432 15.718  -40.303 1.00 13.97 ? 180  MET H O   1 
ATOM   1997 C CB  . MET B 2  185 ? -36.100 14.957  -38.327 1.00 13.84 ? 180  MET H CB  1 
ATOM   1998 C CG  . MET B 2  185 ? -35.505 15.156  -36.959 1.00 15.80 ? 180  MET H CG  1 
ATOM   1999 S SD  . MET B 2  185 ? -35.565 13.551  -36.097 1.00 15.32 ? 180  MET H SD  1 
ATOM   2000 C CE  . MET B 2  185 ? -35.131 14.066  -34.474 1.00 16.91 ? 180  MET H CE  1 
ATOM   2001 N N   . PHE B 2  186 ? -36.530 15.223  -41.391 1.00 12.64 ? 181  PHE H N   1 
ATOM   2002 C CA  . PHE B 2  186 ? -37.230 14.552  -42.477 1.00 12.72 ? 181  PHE H CA  1 
ATOM   2003 C C   . PHE B 2  186 ? -36.278 13.440  -42.869 1.00 11.59 ? 181  PHE H C   1 
ATOM   2004 O O   . PHE B 2  186 ? -35.110 13.465  -42.500 1.00 11.82 ? 181  PHE H O   1 
ATOM   2005 C CB  . PHE B 2  186 ? -37.581 15.477  -43.660 1.00 13.03 ? 181  PHE H CB  1 
ATOM   2006 C CG  . PHE B 2  186 ? -36.399 16.004  -44.433 1.00 11.72 ? 181  PHE H CG  1 
ATOM   2007 C CD1 . PHE B 2  186 ? -35.830 15.263  -45.469 1.00 12.50 ? 181  PHE H CD1 1 
ATOM   2008 C CD2 . PHE B 2  186 ? -35.906 17.280  -44.172 1.00 12.97 ? 181  PHE H CD2 1 
ATOM   2009 C CE1 . PHE B 2  186 ? -34.790 15.786  -46.239 1.00 12.87 ? 181  PHE H CE1 1 
ATOM   2010 C CE2 . PHE B 2  186 ? -34.865 17.814  -44.938 1.00 13.38 ? 181  PHE H CE2 1 
ATOM   2011 C CZ  . PHE B 2  186 ? -34.308 17.072  -45.969 1.00 13.01 ? 181  PHE H CZ  1 
ATOM   2012 N N   . CYS B 2  187 ? -36.773 12.422  -43.557 1.00 12.00 ? 182  CYS H N   1 
ATOM   2013 C CA  . CYS B 2  187 ? -35.878 11.349  -43.955 1.00 11.89 ? 182  CYS H CA  1 
ATOM   2014 C C   . CYS B 2  187 ? -35.953 11.162  -45.463 1.00 10.53 ? 182  CYS H C   1 
ATOM   2015 O O   . CYS B 2  187 ? -36.930 11.553  -46.106 1.00 11.88 ? 182  CYS H O   1 
ATOM   2016 C CB  . CYS B 2  187 ? -36.201 10.059  -43.179 1.00 13.18 ? 182  CYS H CB  1 
ATOM   2017 S SG  . CYS B 2  187 ? -37.440 8.909   -43.866 1.00 13.64 ? 182  CYS H SG  1 
ATOM   2018 N N   . ALA B 2  188 ? -34.895 10.598  -46.034 1.00 11.28 ? 183  ALA H N   1 
ATOM   2019 C CA  . ALA B 2  188 ? -34.848 10.396  -47.471 1.00 11.09 ? 183  ALA H CA  1 
ATOM   2020 C C   . ALA B 2  188 ? -34.080 9.124   -47.796 1.00 11.03 ? 183  ALA H C   1 
ATOM   2021 O O   . ALA B 2  188 ? -33.257 8.651   -47.005 1.00 11.11 ? 183  ALA H O   1 
ATOM   2022 C CB  . ALA B 2  188 ? -34.203 11.596  -48.149 1.00 13.64 ? 183  ALA H CB  1 
ATOM   2023 N N   . GLY B 2  189 ? -34.367 8.579   -48.966 1.00 12.62 ? 184  GLY H N   1 
ATOM   2024 C CA  . GLY B 2  189 ? -33.711 7.362   -49.382 1.00 12.75 ? 184  GLY H CA  1 
ATOM   2025 C C   . GLY B 2  189 ? -34.688 6.502   -50.142 1.00 14.14 ? 184  GLY H C   1 
ATOM   2026 O O   . GLY B 2  189 ? -35.908 6.697   -50.098 1.00 12.47 ? 184  GLY H O   1 
ATOM   2027 N N   . TYR B 2  190 A -34.140 5.526   -50.845 1.00 14.67 ? 184  TYR H N   1 
ATOM   2028 C CA  . TYR B 2  190 A -34.962 4.633   -51.623 1.00 15.55 ? 184  TYR H CA  1 
ATOM   2029 C C   . TYR B 2  190 A -35.521 3.465   -50.845 1.00 17.28 ? 184  TYR H C   1 
ATOM   2030 O O   . TYR B 2  190 A -35.016 3.048   -49.806 1.00 15.19 ? 184  TYR H O   1 
ATOM   2031 C CB  . TYR B 2  190 A -34.155 4.054   -52.781 1.00 16.62 ? 184  TYR H CB  1 
ATOM   2032 C CG  . TYR B 2  190 A -33.854 5.032   -53.878 1.00 14.37 ? 184  TYR H CG  1 
ATOM   2033 C CD1 . TYR B 2  190 A -34.837 5.400   -54.793 1.00 16.17 ? 184  TYR H CD1 1 
ATOM   2034 C CD2 . TYR B 2  190 A -32.588 5.599   -53.998 1.00 16.40 ? 184  TYR H CD2 1 
ATOM   2035 C CE1 . TYR B 2  190 A -34.573 6.312   -55.806 1.00 17.10 ? 184  TYR H CE1 1 
ATOM   2036 C CE2 . TYR B 2  190 A -32.313 6.517   -55.011 1.00 17.19 ? 184  TYR H CE2 1 
ATOM   2037 C CZ  . TYR B 2  190 A -33.308 6.866   -55.909 1.00 18.54 ? 184  TYR H CZ  1 
ATOM   2038 O OH  . TYR B 2  190 A -33.045 7.772   -56.916 1.00 21.95 ? 184  TYR H OH  1 
ATOM   2039 N N   A LYS B 2  191 ? -36.346 2.783   -51.636 0.10 17.74 ? 185  LYS H N   1 
ATOM   2040 N N   B LYS B 2  191 ? -36.739 3.102   -51.233 0.85 18.39 ? 185  LYS H N   1 
ATOM   2041 C CA  A LYS B 2  191 ? -37.014 1.520   -51.374 0.13 19.11 ? 185  LYS H CA  1 
ATOM   2042 C CA  B LYS B 2  191 ? -37.449 2.024   -50.566 0.69 20.80 ? 185  LYS H CA  1 
ATOM   2043 C C   A LYS B 2  191 ? -37.002 0.950   -49.946 0.10 20.26 ? 185  LYS H C   1 
ATOM   2044 C C   B LYS B 2  191 ? -36.986 0.722   -51.175 0.90 21.31 ? 185  LYS H C   1 
ATOM   2045 O O   A LYS B 2  191 ? -37.276 1.691   -49.001 0.10 20.59 ? 185  LYS H O   1 
ATOM   2046 O O   B LYS B 2  191 ? -36.570 0.686   -52.330 0.59 21.35 ? 185  LYS H O   1 
ATOM   2047 C CB  A LYS B 2  191 ? -36.420 0.549   -52.388 0.10 18.73 ? 185  LYS H CB  1 
ATOM   2048 C CB  B LYS B 2  191 ? -38.964 2.191   -50.734 0.90 21.62 ? 185  LYS H CB  1 
ATOM   2049 C CG  A LYS B 2  191 ? -34.899 0.460   -52.347 0.61 17.61 ? 185  LYS H CG  1 
ATOM   2050 C CG  B LYS B 2  191 ? -39.517 3.482   -50.132 0.38 22.92 ? 185  LYS H CG  1 
ATOM   2051 C CD  A LYS B 2  191 ? -34.349 -0.113  -53.634 0.51 18.33 ? 185  LYS H CD  1 
ATOM   2052 C CD  B LYS B 2  191 ? -41.004 3.660   -50.424 0.49 24.26 ? 185  LYS H CD  1 
ATOM   2053 C CE  A LYS B 2  191 ? -32.842 -0.202  -53.588 0.52 16.60 ? 185  LYS H CE  1 
ATOM   2054 C CE  B LYS B 2  191 ? -41.536 4.944   -49.793 0.48 25.70 ? 185  LYS H CE  1 
ATOM   2055 N NZ  A LYS B 2  191 ? -32.274 -0.583  -54.908 0.10 17.69 ? 185  LYS H NZ  1 
ATOM   2056 N NZ  B LYS B 2  191 ? -42.991 5.149   -50.039 0.54 27.26 ? 185  LYS H NZ  1 
ATOM   2057 N N   A PRO B 2  192 ? -36.691 -0.359  -49.747 0.10 21.48 ? 186  PRO H N   1 
ATOM   2058 N N   B PRO B 2  192 ? -37.045 -0.368  -50.399 0.59 22.85 ? 186  PRO H N   1 
ATOM   2059 C CA  A PRO B 2  192 ? -36.311 -1.581  -50.485 0.31 22.27 ? 186  PRO H CA  1 
ATOM   2060 C CA  B PRO B 2  192 ? -36.626 -1.695  -50.851 0.40 24.15 ? 186  PRO H CA  1 
ATOM   2061 C C   A PRO B 2  192 ? -37.056 -2.018  -51.754 0.10 23.01 ? 186  PRO H C   1 
ATOM   2062 C C   B PRO B 2  192 ? -37.159 -2.076  -52.228 0.42 25.08 ? 186  PRO H C   1 
ATOM   2063 O O   A PRO B 2  192 ? -36.613 -2.943  -52.434 0.28 22.52 ? 186  PRO H O   1 
ATOM   2064 O O   B PRO B 2  192 ? -36.468 -2.727  -53.008 0.63 25.26 ? 186  PRO H O   1 
ATOM   2065 C CB  A PRO B 2  192 ? -36.370 -2.659  -49.409 0.22 22.22 ? 186  PRO H CB  1 
ATOM   2066 C CB  B PRO B 2  192 ? -37.155 -2.609  -49.751 0.40 24.02 ? 186  PRO H CB  1 
ATOM   2067 C CG  A PRO B 2  192 ? -35.906 -1.938  -48.228 0.45 21.81 ? 186  PRO H CG  1 
ATOM   2068 C CG  B PRO B 2  192 ? -37.018 -1.750  -48.528 0.55 23.18 ? 186  PRO H CG  1 
ATOM   2069 C CD  A PRO B 2  192 ? -36.709 -0.659  -48.304 0.10 21.67 ? 186  PRO H CD  1 
ATOM   2070 C CD  B PRO B 2  192 ? -37.555 -0.422  -49.017 0.70 22.90 ? 186  PRO H CD  1 
ATOM   2071 N N   A ASP B 2  193 A -38.166 -1.364  -52.080 0.49 23.83 ? 186  ASP H N   1 
ATOM   2072 N N   B ASP B 2  193 A -38.382 -1.650  -52.527 0.40 26.17 ? 186  ASP H N   1 
ATOM   2073 C CA  A ASP B 2  193 A -38.918 -1.714  -53.282 0.10 25.08 ? 186  ASP H CA  1 
ATOM   2074 C CA  B ASP B 2  193 A -39.017 -1.973  -53.801 0.37 26.86 ? 186  ASP H CA  1 
ATOM   2075 C C   A ASP B 2  193 A -38.887 -0.607  -54.344 0.45 25.81 ? 186  ASP H C   1 
ATOM   2076 C C   B ASP B 2  193 A -38.742 -0.996  -54.943 0.55 27.22 ? 186  ASP H C   1 
ATOM   2077 O O   A ASP B 2  193 A -39.924 -0.028  -54.669 0.31 26.39 ? 186  ASP H O   1 
ATOM   2078 O O   B ASP B 2  193 A -39.188 -1.219  -56.068 0.65 26.94 ? 186  ASP H O   1 
ATOM   2079 C CB  A ASP B 2  193 A -40.371 -2.031  -52.915 0.28 25.01 ? 186  ASP H CB  1 
ATOM   2080 C CB  B ASP B 2  193 A -40.531 -2.103  -53.603 0.58 28.42 ? 186  ASP H CB  1 
ATOM   2081 N N   A GLU B 2  194 B -37.704 -0.321  -54.888 0.29 26.60 ? 186  GLU H N   1 
ATOM   2082 N N   B GLU B 2  194 B -38.012 0.081   -54.670 0.55 26.68 ? 186  GLU H N   1 
ATOM   2083 C CA  A GLU B 2  194 B -37.564 0.717   -55.911 0.33 26.95 ? 186  GLU H CA  1 
ATOM   2084 C CA  B GLU B 2  194 B -37.725 1.056   -55.714 0.67 26.23 ? 186  GLU H CA  1 
ATOM   2085 C C   A GLU B 2  194 B -36.464 0.456   -56.942 0.11 26.82 ? 186  GLU H C   1 
ATOM   2086 C C   B GLU B 2  194 B -36.544 0.695   -56.617 0.83 26.08 ? 186  GLU H C   1 
ATOM   2087 O O   A GLU B 2  194 B -36.505 0.999   -58.047 0.10 26.93 ? 186  GLU H O   1 
ATOM   2088 O O   B GLU B 2  194 B -36.287 1.372   -57.613 0.45 26.46 ? 186  GLU H O   1 
ATOM   2089 C CB  A GLU B 2  194 B -37.338 2.087   -55.259 0.10 27.64 ? 186  GLU H CB  1 
ATOM   2090 C CB  B GLU B 2  194 B -37.547 2.449   -55.095 0.90 24.93 ? 186  GLU H CB  1 
ATOM   2091 C CG  A GLU B 2  194 B -38.591 2.684   -54.633 0.42 28.75 ? 186  GLU H CG  1 
ATOM   2092 C CG  B GLU B 2  194 B -38.869 2.996   -54.565 0.24 24.92 ? 186  GLU H CG  1 
ATOM   2093 C CD  A GLU B 2  194 B -38.388 4.108   -54.150 0.10 29.16 ? 186  GLU H CD  1 
ATOM   2094 C CD  B GLU B 2  194 B -38.807 4.458   -54.186 0.84 24.48 ? 186  GLU H CD  1 
ATOM   2095 O OE1 A GLU B 2  194 B -37.580 4.317   -53.222 0.10 29.82 ? 186  GLU H OE1 1 
ATOM   2096 O OE1 B GLU B 2  194 B -38.071 4.796   -53.243 0.90 23.14 ? 186  GLU H OE1 1 
ATOM   2097 O OE2 A GLU B 2  194 B -39.037 5.022   -54.700 0.14 29.60 ? 186  GLU H OE2 1 
ATOM   2098 O OE2 B GLU B 2  194 B -39.501 5.268   -54.837 0.38 24.84 ? 186  GLU H OE2 1 
ATOM   2099 N N   A GLY B 2  195 C -35.478 -0.361  -56.583 0.10 26.62 ? 186  GLY H N   1 
ATOM   2100 N N   B GLY B 2  195 C -35.832 -0.372  -56.268 0.53 26.37 ? 186  GLY H N   1 
ATOM   2101 C CA  A GLY B 2  195 C -34.409 -0.677  -57.516 0.68 26.46 ? 186  GLY H CA  1 
ATOM   2102 C CA  B GLY B 2  195 C -34.721 -0.831  -57.089 0.32 26.10 ? 186  GLY H CA  1 
ATOM   2103 C C   A GLY B 2  195 C -33.193 0.233   -57.511 0.10 25.54 ? 186  GLY H C   1 
ATOM   2104 C C   B GLY B 2  195 C -33.411 -0.062  -57.136 0.10 25.26 ? 186  GLY H C   1 
ATOM   2105 O O   A GLY B 2  195 C -32.253 0.011   -58.275 0.15 25.74 ? 186  GLY H O   1 
ATOM   2106 O O   B GLY B 2  195 C -32.463 -0.522  -57.771 0.26 25.57 ? 186  GLY H O   1 
ATOM   2107 N N   A LYS B 2  196 D -33.200 1.255   -56.662 0.10 24.49 ? 186  LYS H N   1 
ATOM   2108 N N   B LYS B 2  196 D -33.341 1.098   -56.490 0.64 24.11 ? 186  LYS H N   1 
ATOM   2109 C CA  A LYS B 2  196 D -32.074 2.181   -56.583 0.28 23.31 ? 186  LYS H CA  1 
ATOM   2110 C CA  B LYS B 2  196 D -32.108 1.886   -56.485 0.28 22.86 ? 186  LYS H CA  1 
ATOM   2111 C C   A LYS B 2  196 D -31.656 2.388   -55.130 0.26 22.14 ? 186  LYS H C   1 
ATOM   2112 C C   B LYS B 2  196 D -31.602 2.041   -55.056 0.74 21.04 ? 186  LYS H C   1 
ATOM   2113 O O   A LYS B 2  196 D -32.498 2.467   -54.243 0.10 22.43 ? 186  LYS H O   1 
ATOM   2114 O O   B LYS B 2  196 D -32.338 1.767   -54.108 0.75 20.46 ? 186  LYS H O   1 
ATOM   2115 C CB  A LYS B 2  196 D -32.452 3.521   -57.224 0.46 23.53 ? 186  LYS H CB  1 
ATOM   2116 C CB  B LYS B 2  196 D -32.349 3.270   -57.095 0.46 23.61 ? 186  LYS H CB  1 
ATOM   2117 C CG  A LYS B 2  196 D -32.836 3.408   -58.693 0.12 23.68 ? 186  LYS H CG  1 
ATOM   2118 C CG  B LYS B 2  196 D -32.774 3.256   -58.553 0.76 24.42 ? 186  LYS H CG  1 
ATOM   2119 C CD  A LYS B 2  196 D -33.261 4.747   -59.277 0.18 23.90 ? 186  LYS H CD  1 
ATOM   2120 C CD  B LYS B 2  196 D -32.841 4.666   -59.122 0.38 24.64 ? 186  LYS H CD  1 
ATOM   2121 C CE  A LYS B 2  196 D -33.673 4.597   -60.736 0.53 23.95 ? 186  LYS H CE  1 
ATOM   2122 C CE  B LYS B 2  196 D -31.469 5.328   -59.123 0.47 25.13 ? 186  LYS H CE  1 
ATOM   2123 N NZ  A LYS B 2  196 D -34.128 5.880   -61.343 0.42 24.99 ? 186  LYS H NZ  1 
ATOM   2124 N NZ  B LYS B 2  196 D -31.519 6.731   -59.617 0.39 25.35 ? 186  LYS H NZ  1 
ATOM   2125 N N   . ARG B 2  197 ? -30.350 2.469   -54.895 1.00 20.73 ? 187  ARG H N   1 
ATOM   2126 C CA  . ARG B 2  197 ? -29.801 2.652   -53.548 1.00 20.07 ? 187  ARG H CA  1 
ATOM   2127 C C   . ARG B 2  197 ? -29.106 4.000   -53.367 1.00 17.14 ? 187  ARG H C   1 
ATOM   2128 O O   . ARG B 2  197 ? -29.052 4.813   -54.286 1.00 18.07 ? 187  ARG H O   1 
ATOM   2129 C CB  . ARG B 2  197 ? -28.799 1.543   -53.221 1.00 24.48 ? 187  ARG H CB  1 
ATOM   2130 C CG  . ARG B 2  197 ? -29.275 0.129   -53.535 1.00 27.17 ? 187  ARG H CG  1 
ATOM   2131 C CD  . ARG B 2  197 ? -28.308 -0.885  -52.939 1.00 29.30 ? 187  ARG H CD  1 
ATOM   2132 N NE  . ARG B 2  197 ? -28.390 -0.904  -51.482 1.00 31.14 ? 187  ARG H NE  1 
ATOM   2133 C CZ  . ARG B 2  197 ? -29.419 -1.397  -50.799 1.00 32.06 ? 187  ARG H CZ  1 
ATOM   2134 N NH1 . ARG B 2  197 ? -30.454 -1.922  -51.445 1.00 34.76 ? 187  ARG H NH1 1 
ATOM   2135 N NH2 . ARG B 2  197 ? -29.423 -1.358  -49.474 1.00 30.58 ? 187  ARG H NH2 1 
ATOM   2136 N N   . GLY B 2  198 ? -28.567 4.222   -52.171 1.00 16.16 ? 188  GLY H N   1 
ATOM   2137 C CA  . GLY B 2  198 ? -27.876 5.470   -51.901 1.00 14.96 ? 188  GLY H CA  1 
ATOM   2138 C C   . GLY B 2  198 ? -28.179 6.016   -50.522 1.00 14.21 ? 188  GLY H C   1 
ATOM   2139 O O   . GLY B 2  198 ? -29.311 5.912   -50.041 1.00 13.10 ? 188  GLY H O   1 
ATOM   2140 N N   . ASP B 2  199 ? -27.174 6.615   -49.888 1.00 12.62 ? 189  ASP H N   1 
ATOM   2141 C CA  . ASP B 2  199 ? -27.353 7.164   -48.550 1.00 12.73 ? 189  ASP H CA  1 
ATOM   2142 C C   . ASP B 2  199 ? -26.115 7.963   -48.159 1.00 13.44 ? 189  ASP H C   1 
ATOM   2143 O O   . ASP B 2  199 ? -25.078 7.896   -48.826 1.00 13.80 ? 189  ASP H O   1 
ATOM   2144 C CB  . ASP B 2  199 ? -27.567 6.001   -47.569 1.00 12.70 ? 189  ASP H CB  1 
ATOM   2145 C CG  . ASP B 2  199 ? -28.036 6.439   -46.184 1.00 13.78 ? 189  ASP H CG  1 
ATOM   2146 O OD1 . ASP B 2  199 ? -28.439 7.608   -45.984 1.00 13.06 ? 189  ASP H OD1 1 
ATOM   2147 O OD2 . ASP B 2  199 ? -28.020 5.574   -45.279 1.00 14.07 ? 189  ASP H OD2 1 
ATOM   2148 N N   . ALA B 2  200 ? -26.233 8.744   -47.094 1.00 13.27 ? 190  ALA H N   1 
ATOM   2149 C CA  . ALA B 2  200 ? -25.084 9.480   -46.588 1.00 13.81 ? 190  ALA H CA  1 
ATOM   2150 C C   . ALA B 2  200 ? -24.465 8.495   -45.596 1.00 14.99 ? 190  ALA H C   1 
ATOM   2151 O O   . ALA B 2  200 ? -25.072 7.463   -45.292 1.00 15.78 ? 190  ALA H O   1 
ATOM   2152 C CB  . ALA B 2  200 ? -25.530 10.747  -45.873 1.00 13.20 ? 190  ALA H CB  1 
ATOM   2153 N N   . CYS B 2  201 ? -23.271 8.795   -45.096 1.00 14.22 ? 191  CYS H N   1 
ATOM   2154 C CA  . CYS B 2  201 ? -22.613 7.905   -44.148 1.00 15.39 ? 191  CYS H CA  1 
ATOM   2155 C C   . CYS B 2  201 ? -21.602 8.654   -43.285 1.00 16.47 ? 191  CYS H C   1 
ATOM   2156 O O   . CYS B 2  201 ? -21.569 9.887   -43.283 1.00 13.90 ? 191  CYS H O   1 
ATOM   2157 C CB  . CYS B 2  201 ? -21.936 6.754   -44.905 1.00 17.46 ? 191  CYS H CB  1 
ATOM   2158 S SG  . CYS B 2  201 ? -21.618 5.253   -43.911 1.00 19.33 ? 191  CYS H SG  1 
ATOM   2159 N N   . GLU B 2  202 ? -20.788 7.910   -42.542 1.00 16.19 ? 192  GLU H N   1 
ATOM   2160 C CA  . GLU B 2  202 ? -19.784 8.496   -41.657 1.00 17.13 ? 192  GLU H CA  1 
ATOM   2161 C C   . GLU B 2  202 ? -18.913 9.542   -42.349 1.00 16.23 ? 192  GLU H C   1 
ATOM   2162 O O   . GLU B 2  202 ? -18.226 9.247   -43.323 1.00 17.80 ? 192  GLU H O   1 
ATOM   2163 C CB  . GLU B 2  202 ? -18.898 7.388   -41.083 1.00 20.85 ? 192  GLU H CB  1 
ATOM   2164 C CG  . GLU B 2  202 ? -17.927 7.854   -40.031 1.00 24.11 ? 192  GLU H CG  1 
ATOM   2165 C CD  . GLU B 2  202 ? -17.060 6.722   -39.525 1.00 28.79 ? 192  GLU H CD  1 
ATOM   2166 O OE1 . GLU B 2  202 ? -17.614 5.640   -39.247 1.00 29.42 ? 192  GLU H OE1 1 
ATOM   2167 O OE2 . GLU B 2  202 ? -15.835 6.917   -39.402 1.00 31.33 ? 192  GLU H OE2 1 
ATOM   2168 N N   . GLY B 2  203 ? -18.940 10.768  -41.830 1.00 15.89 ? 193  GLY H N   1 
ATOM   2169 C CA  . GLY B 2  203 ? -18.155 11.831  -42.426 1.00 15.90 ? 193  GLY H CA  1 
ATOM   2170 C C   . GLY B 2  203 ? -18.978 12.793  -43.269 1.00 16.46 ? 193  GLY H C   1 
ATOM   2171 O O   . GLY B 2  203 ? -18.493 13.863  -43.644 1.00 15.80 ? 193  GLY H O   1 
ATOM   2172 N N   . ASP B 2  204 ? -20.228 12.431  -43.553 1.00 14.08 ? 194  ASP H N   1 
ATOM   2173 C CA  . ASP B 2  204 ? -21.098 13.287  -44.366 1.00 14.60 ? 194  ASP H CA  1 
ATOM   2174 C C   . ASP B 2  204 ? -21.994 14.202  -43.543 1.00 13.45 ? 194  ASP H C   1 
ATOM   2175 O O   . ASP B 2  204 ? -22.608 15.112  -44.096 1.00 12.96 ? 194  ASP H O   1 
ATOM   2176 C CB  . ASP B 2  204 ? -22.012 12.456  -45.271 1.00 12.79 ? 194  ASP H CB  1 
ATOM   2177 C CG  . ASP B 2  204 ? -21.260 11.724  -46.359 1.00 14.15 ? 194  ASP H CG  1 
ATOM   2178 O OD1 . ASP B 2  204 ? -20.368 12.328  -46.983 1.00 12.42 ? 194  ASP H OD1 1 
ATOM   2179 O OD2 . ASP B 2  204 ? -21.573 10.535  -46.599 1.00 14.62 ? 194  ASP H OD2 1 
ATOM   2180 N N   . ALA B 2  205 ? -22.085 13.956  -42.239 1.00 12.29 ? 195  ALA H N   1 
ATOM   2181 C CA  . ALA B 2  205 ? -22.944 14.770  -41.383 1.00 10.74 ? 195  ALA H CA  1 
ATOM   2182 C C   . ALA B 2  205 ? -22.584 16.231  -41.542 1.00 12.45 ? 195  ALA H C   1 
ATOM   2183 O O   . ALA B 2  205 ? -21.426 16.568  -41.755 1.00 12.42 ? 195  ALA H O   1 
ATOM   2184 C CB  . ALA B 2  205 ? -22.787 14.363  -39.928 1.00 12.50 ? 195  ALA H CB  1 
ATOM   2185 N N   . GLY B 2  206 ? -23.585 17.095  -41.436 1.00 11.36 ? 196  GLY H N   1 
ATOM   2186 C CA  . GLY B 2  206 ? -23.320 18.519  -41.566 1.00 11.09 ? 196  GLY H CA  1 
ATOM   2187 C C   . GLY B 2  206 ? -23.415 19.023  -42.995 1.00 12.03 ? 196  GLY H C   1 
ATOM   2188 O O   . GLY B 2  206 ? -23.574 20.225  -43.226 1.00 11.56 ? 196  GLY H O   1 
ATOM   2189 N N   . GLY B 2  207 ? -23.306 18.106  -43.955 1.00 9.98  ? 197  GLY H N   1 
ATOM   2190 C CA  . GLY B 2  207 ? -23.402 18.464  -45.359 1.00 11.54 ? 197  GLY H CA  1 
ATOM   2191 C C   . GLY B 2  207 ? -24.818 18.843  -45.762 1.00 10.78 ? 197  GLY H C   1 
ATOM   2192 O O   . GLY B 2  207 ? -25.776 18.592  -45.026 1.00 12.06 ? 197  GLY H O   1 
ATOM   2193 N N   . PRO B 2  208 ? -24.991 19.417  -46.951 1.00 11.43 ? 198  PRO H N   1 
ATOM   2194 C CA  . PRO B 2  208 ? -26.323 19.821  -47.394 1.00 10.41 ? 198  PRO H CA  1 
ATOM   2195 C C   . PRO B 2  208 ? -27.132 18.823  -48.213 1.00 13.35 ? 198  PRO H C   1 
ATOM   2196 O O   . PRO B 2  208 ? -26.577 18.027  -48.965 1.00 14.09 ? 198  PRO H O   1 
ATOM   2197 C CB  . PRO B 2  208 ? -26.023 21.073  -48.201 1.00 12.50 ? 198  PRO H CB  1 
ATOM   2198 C CG  . PRO B 2  208 ? -24.765 20.632  -48.952 1.00 10.66 ? 198  PRO H CG  1 
ATOM   2199 C CD  . PRO B 2  208 ? -23.951 19.915  -47.877 1.00 10.75 ? 198  PRO H CD  1 
ATOM   2200 N N   . PHE B 2  209 ? -28.449 18.867  -48.015 1.00 11.50 ? 199  PHE H N   1 
ATOM   2201 C CA  . PHE B 2  209 ? -29.409 18.099  -48.797 1.00 11.40 ? 199  PHE H CA  1 
ATOM   2202 C C   . PHE B 2  209 ? -30.035 19.261  -49.574 1.00 11.26 ? 199  PHE H C   1 
ATOM   2203 O O   . PHE B 2  209 ? -30.716 20.119  -48.991 1.00 10.62 ? 199  PHE H O   1 
ATOM   2204 C CB  . PHE B 2  209 ? -30.457 17.425  -47.904 1.00 10.96 ? 199  PHE H CB  1 
ATOM   2205 C CG  . PHE B 2  209 ? -31.545 16.709  -48.669 1.00 11.77 ? 199  PHE H CG  1 
ATOM   2206 C CD1 . PHE B 2  209 ? -32.575 17.419  -49.279 1.00 12.09 ? 199  PHE H CD1 1 
ATOM   2207 C CD2 . PHE B 2  209 ? -31.536 15.320  -48.781 1.00 13.74 ? 199  PHE H CD2 1 
ATOM   2208 C CE1 . PHE B 2  209 ? -33.584 16.767  -49.987 1.00 12.32 ? 199  PHE H CE1 1 
ATOM   2209 C CE2 . PHE B 2  209 ? -32.540 14.658  -49.491 1.00 11.68 ? 199  PHE H CE2 1 
ATOM   2210 C CZ  . PHE B 2  209 ? -33.566 15.382  -50.095 1.00 11.97 ? 199  PHE H CZ  1 
ATOM   2211 N N   . VAL B 2  210 ? -29.779 19.322  -50.874 1.00 7.85  ? 200  VAL H N   1 
ATOM   2212 C CA  . VAL B 2  210 ? -30.300 20.422  -51.679 1.00 10.18 ? 200  VAL H CA  1 
ATOM   2213 C C   . VAL B 2  210 ? -31.310 19.985  -52.722 1.00 11.56 ? 200  VAL H C   1 
ATOM   2214 O O   . VAL B 2  210 ? -31.382 18.813  -53.089 1.00 11.03 ? 200  VAL H O   1 
ATOM   2215 C CB  . VAL B 2  210 ? -29.160 21.168  -52.407 1.00 11.45 ? 200  VAL H CB  1 
ATOM   2216 C CG1 . VAL B 2  210 ? -28.122 21.636  -51.399 1.00 13.88 ? 200  VAL H CG1 1 
ATOM   2217 C CG2 . VAL B 2  210 ? -28.523 20.252  -53.463 1.00 12.30 ? 200  VAL H CG2 1 
ATOM   2218 N N   . MET B 2  211 ? -32.107 20.944  -53.176 1.00 10.27 ? 201  MET H N   1 
ATOM   2219 C CA  . MET B 2  211 ? -33.101 20.686  -54.199 1.00 9.51  ? 201  MET H CA  1 
ATOM   2220 C C   . MET B 2  211 ? -33.087 21.859  -55.149 1.00 13.04 ? 201  MET H C   1 
ATOM   2221 O O   . MET B 2  211 ? -32.867 22.997  -54.729 1.00 13.75 ? 201  MET H O   1 
ATOM   2222 C CB  . MET B 2  211 ? -34.491 20.538  -53.574 1.00 10.80 ? 201  MET H CB  1 
ATOM   2223 C CG  . MET B 2  211 ? -34.586 19.374  -52.590 1.00 11.45 ? 201  MET H CG  1 
ATOM   2224 S SD  . MET B 2  211 ? -36.274 19.091  -52.035 1.00 12.96 ? 201  MET H SD  1 
ATOM   2225 C CE  . MET B 2  211 ? -36.917 18.077  -53.372 1.00 14.96 ? 201  MET H CE  1 
ATOM   2226 N N   . LYS B 2  212 ? -33.298 21.584  -56.430 1.00 13.08 ? 202  LYS H N   1 
ATOM   2227 C CA  . LYS B 2  212 ? -33.329 22.649  -57.413 1.00 14.22 ? 202  LYS H CA  1 
ATOM   2228 C C   . LYS B 2  212 ? -34.762 23.082  -57.650 1.00 14.68 ? 202  LYS H C   1 
ATOM   2229 O O   . LYS B 2  212 ? -35.637 22.265  -57.951 1.00 15.55 ? 202  LYS H O   1 
ATOM   2230 C CB  . LYS B 2  212 ? -32.685 22.205  -58.727 1.00 15.38 ? 202  LYS H CB  1 
ATOM   2231 C CG  . LYS B 2  212 ? -32.688 23.292  -59.788 1.00 20.16 ? 202  LYS H CG  1 
ATOM   2232 C CD  . LYS B 2  212 ? -31.549 23.108  -60.783 1.00 18.37 ? 202  LYS H CD  1 
ATOM   2233 C CE  . LYS B 2  212 ? -31.580 24.196  -61.829 1.00 20.93 ? 202  LYS H CE  1 
ATOM   2234 N NZ  . LYS B 2  212 ? -30.474 24.095  -62.811 1.00 18.04 ? 202  LYS H NZ  1 
ATOM   2235 N N   . SER B 2  213 ? -35.007 24.377  -57.485 1.00 12.09 ? 203  SER H N   1 
ATOM   2236 C CA  . SER B 2  213 ? -36.337 24.915  -57.696 1.00 13.26 ? 203  SER H CA  1 
ATOM   2237 C C   . SER B 2  213 ? -36.591 25.115  -59.185 1.00 14.63 ? 203  SER H C   1 
ATOM   2238 O O   . SER B 2  213 ? -35.824 25.784  -59.873 1.00 13.63 ? 203  SER H O   1 
ATOM   2239 C CB  . SER B 2  213 ? -36.492 26.262  -56.993 1.00 15.59 ? 203  SER H CB  1 
ATOM   2240 O OG  . SER B 2  213 ? -37.706 26.883  -57.389 1.00 16.18 ? 203  SER H OG  1 
ATOM   2241 N N   . PRO B 2  214 ? -37.676 24.531  -59.701 1.00 15.54 ? 204  PRO H N   1 
ATOM   2242 C CA  . PRO B 2  214 ? -37.994 24.681  -61.122 1.00 16.74 ? 204  PRO H CA  1 
ATOM   2243 C C   . PRO B 2  214 ? -38.628 26.046  -61.377 1.00 17.09 ? 204  PRO H C   1 
ATOM   2244 O O   . PRO B 2  214 ? -38.786 26.472  -62.527 1.00 20.08 ? 204  PRO H O   1 
ATOM   2245 C CB  . PRO B 2  214 ? -38.960 23.528  -61.373 1.00 16.79 ? 204  PRO H CB  1 
ATOM   2246 C CG  . PRO B 2  214 ? -39.714 23.451  -60.074 1.00 17.43 ? 204  PRO H CG  1 
ATOM   2247 C CD  . PRO B 2  214 ? -38.611 23.603  -59.037 1.00 14.91 ? 204  PRO H CD  1 
ATOM   2248 N N   . PHE B 2  215 A -38.960 26.740  -60.291 1.00 15.19 ? 204  PHE H N   1 
ATOM   2249 C CA  . PHE B 2  215 A -39.604 28.050  -60.368 1.00 15.82 ? 204  PHE H CA  1 
ATOM   2250 C C   . PHE B 2  215 A -38.638 29.212  -60.585 1.00 16.83 ? 204  PHE H C   1 
ATOM   2251 O O   . PHE B 2  215 A -39.016 30.237  -61.157 1.00 17.44 ? 204  PHE H O   1 
ATOM   2252 C CB  . PHE B 2  215 A -40.447 28.256  -59.110 1.00 15.82 ? 204  PHE H CB  1 
ATOM   2253 C CG  . PHE B 2  215 A -41.304 27.074  -58.789 1.00 17.21 ? 204  PHE H CG  1 
ATOM   2254 C CD1 . PHE B 2  215 A -42.308 26.673  -59.667 1.00 19.91 ? 204  PHE H CD1 1 
ATOM   2255 C CD2 . PHE B 2  215 A -41.059 26.307  -57.656 1.00 17.54 ? 204  PHE H CD2 1 
ATOM   2256 C CE1 . PHE B 2  215 A -43.052 25.518  -59.424 1.00 22.02 ? 204  PHE H CE1 1 
ATOM   2257 C CE2 . PHE B 2  215 A -41.793 25.153  -57.404 1.00 18.16 ? 204  PHE H CE2 1 
ATOM   2258 C CZ  . PHE B 2  215 A -42.791 24.756  -58.289 1.00 19.49 ? 204  PHE H CZ  1 
ATOM   2259 N N   . ASN B 2  216 B -37.396 29.073  -60.132 1.00 15.39 ? 204  ASN H N   1 
ATOM   2260 C CA  . ASN B 2  216 B -36.416 30.128  -60.361 1.00 15.65 ? 204  ASN H CA  1 
ATOM   2261 C C   . ASN B 2  216 B -35.033 29.583  -60.710 1.00 15.41 ? 204  ASN H C   1 
ATOM   2262 O O   . ASN B 2  216 B -34.058 30.332  -60.795 1.00 16.89 ? 204  ASN H O   1 
ATOM   2263 C CB  . ASN B 2  216 B -36.341 31.100  -59.176 1.00 14.83 ? 204  ASN H CB  1 
ATOM   2264 C CG  . ASN B 2  216 B -35.889 30.439  -57.891 1.00 15.50 ? 204  ASN H CG  1 
ATOM   2265 O OD1 . ASN B 2  216 B -35.483 29.274  -57.874 1.00 13.61 ? 204  ASN H OD1 1 
ATOM   2266 N ND2 . ASN B 2  216 B -35.955 31.192  -56.800 1.00 13.64 ? 204  ASN H ND2 1 
ATOM   2267 N N   . ASN B 2  217 ? -34.969 28.270  -60.933 1.00 15.31 ? 205  ASN H N   1 
ATOM   2268 C CA  . ASN B 2  217 ? -33.743 27.592  -61.328 1.00 14.85 ? 205  ASN H CA  1 
ATOM   2269 C C   . ASN B 2  217 ? -32.622 27.637  -60.290 1.00 14.41 ? 205  ASN H C   1 
ATOM   2270 O O   . ASN B 2  217 ? -31.468 27.385  -60.620 1.00 15.49 ? 205  ASN H O   1 
ATOM   2271 C CB  . ASN B 2  217 ? -33.246 28.193  -62.650 1.00 17.23 ? 205  ASN H CB  1 
ATOM   2272 C CG  . ASN B 2  217 ? -32.375 27.239  -63.432 1.00 18.52 ? 205  ASN H CG  1 
ATOM   2273 O OD1 . ASN B 2  217 ? -32.685 26.057  -63.534 1.00 20.86 ? 205  ASN H OD1 1 
ATOM   2274 N ND2 . ASN B 2  217 ? -31.286 27.751  -64.005 1.00 23.32 ? 205  ASN H ND2 1 
ATOM   2275 N N   . ARG B 2  218 ? -32.957 27.940  -59.038 1.00 14.70 ? 206  ARG H N   1 
ATOM   2276 C CA  . ARG B 2  218 ? -31.949 28.017  -57.981 1.00 13.14 ? 206  ARG H CA  1 
ATOM   2277 C C   . ARG B 2  218 ? -31.910 26.819  -57.044 1.00 12.31 ? 206  ARG H C   1 
ATOM   2278 O O   . ARG B 2  218 ? -32.930 26.178  -56.792 1.00 13.28 ? 206  ARG H O   1 
ATOM   2279 C CB  . ARG B 2  218 ? -32.165 29.268  -57.129 1.00 12.72 ? 206  ARG H CB  1 
ATOM   2280 C CG  . ARG B 2  218 ? -32.003 30.552  -57.896 1.00 13.88 ? 206  ARG H CG  1 
ATOM   2281 C CD  . ARG B 2  218 ? -32.171 31.748  -57.000 1.00 13.25 ? 206  ARG H CD  1 
ATOM   2282 N NE  . ARG B 2  218 ? -32.183 32.978  -57.790 1.00 15.56 ? 206  ARG H NE  1 
ATOM   2283 C CZ  . ARG B 2  218 ? -31.390 34.024  -57.580 1.00 16.14 ? 206  ARG H CZ  1 
ATOM   2284 N NH1 . ARG B 2  218 ? -30.495 34.012  -56.604 1.00 16.44 ? 206  ARG H NH1 1 
ATOM   2285 N NH2 . ARG B 2  218 ? -31.521 35.104  -58.339 1.00 15.39 ? 206  ARG H NH2 1 
ATOM   2286 N N   . TRP B 2  219 ? -30.722 26.539  -56.517 1.00 11.57 ? 207  TRP H N   1 
ATOM   2287 C CA  . TRP B 2  219 ? -30.547 25.449  -55.565 1.00 10.41 ? 207  TRP H CA  1 
ATOM   2288 C C   . TRP B 2  219 ? -30.823 25.941  -54.154 1.00 11.41 ? 207  TRP H C   1 
ATOM   2289 O O   . TRP B 2  219 ? -30.286 26.969  -53.724 1.00 10.56 ? 207  TRP H O   1 
ATOM   2290 C CB  . TRP B 2  219 ? -29.125 24.899  -55.635 1.00 11.20 ? 207  TRP H CB  1 
ATOM   2291 C CG  . TRP B 2  219 ? -28.864 24.217  -56.917 1.00 11.10 ? 207  TRP H CG  1 
ATOM   2292 C CD1 . TRP B 2  219 ? -28.435 24.791  -58.079 1.00 11.97 ? 207  TRP H CD1 1 
ATOM   2293 C CD2 . TRP B 2  219 ? -29.076 22.831  -57.202 1.00 11.46 ? 207  TRP H CD2 1 
ATOM   2294 N NE1 . TRP B 2  219 ? -28.363 23.845  -59.072 1.00 13.31 ? 207  TRP H NE1 1 
ATOM   2295 C CE2 . TRP B 2  219 ? -28.752 22.634  -58.562 1.00 12.15 ? 207  TRP H CE2 1 
ATOM   2296 C CE3 . TRP B 2  219 ? -29.509 21.738  -56.440 1.00 12.92 ? 207  TRP H CE3 1 
ATOM   2297 C CZ2 . TRP B 2  219 ? -28.846 21.384  -59.181 1.00 14.12 ? 207  TRP H CZ2 1 
ATOM   2298 C CZ3 . TRP B 2  219 ? -29.602 20.492  -57.054 1.00 11.58 ? 207  TRP H CZ3 1 
ATOM   2299 C CH2 . TRP B 2  219 ? -29.271 20.329  -58.413 1.00 13.89 ? 207  TRP H CH2 1 
ATOM   2300 N N   . TYR B 2  220 ? -31.664 25.196  -53.443 1.00 9.93  ? 208  TYR H N   1 
ATOM   2301 C CA  . TYR B 2  220 ? -32.042 25.502  -52.072 1.00 8.80  ? 208  TYR H CA  1 
ATOM   2302 C C   . TYR B 2  220 ? -31.611 24.389  -51.136 1.00 9.87  ? 208  TYR H C   1 
ATOM   2303 O O   . TYR B 2  220 ? -31.779 23.206  -51.459 1.00 12.20 ? 208  TYR H O   1 
ATOM   2304 C CB  . TYR B 2  220 ? -33.565 25.631  -51.968 1.00 9.91  ? 208  TYR H CB  1 
ATOM   2305 C CG  . TYR B 2  220 ? -34.126 26.920  -52.503 1.00 10.69 ? 208  TYR H CG  1 
ATOM   2306 C CD1 . TYR B 2  220 ? -34.319 28.012  -51.659 1.00 11.03 ? 208  TYR H CD1 1 
ATOM   2307 C CD2 . TYR B 2  220 ? -34.447 27.057  -53.852 1.00 10.79 ? 208  TYR H CD2 1 
ATOM   2308 C CE1 . TYR B 2  220 ? -34.820 29.215  -52.141 1.00 9.44  ? 208  TYR H CE1 1 
ATOM   2309 C CE2 . TYR B 2  220 ? -34.946 28.266  -54.354 1.00 10.90 ? 208  TYR H CE2 1 
ATOM   2310 C CZ  . TYR B 2  220 ? -35.127 29.336  -53.487 1.00 12.53 ? 208  TYR H CZ  1 
ATOM   2311 O OH  . TYR B 2  220 ? -35.602 30.532  -53.971 1.00 13.48 ? 208  TYR H OH  1 
ATOM   2312 N N   . GLN B 2  221 ? -31.076 24.747  -49.975 1.00 10.55 ? 209  GLN H N   1 
ATOM   2313 C CA  . GLN B 2  221 ? -30.690 23.731  -49.011 1.00 8.95  ? 209  GLN H CA  1 
ATOM   2314 C C   . GLN B 2  221 ? -31.896 23.460  -48.125 1.00 10.80 ? 209  GLN H C   1 
ATOM   2315 O O   . GLN B 2  221 ? -32.282 24.293  -47.297 1.00 10.67 ? 209  GLN H O   1 
ATOM   2316 C CB  . GLN B 2  221 ? -29.518 24.162  -48.135 1.00 10.39 ? 209  GLN H CB  1 
ATOM   2317 C CG  . GLN B 2  221 ? -29.180 23.080  -47.132 1.00 11.54 ? 209  GLN H CG  1 
ATOM   2318 C CD  . GLN B 2  221 ? -27.928 23.359  -46.346 1.00 12.04 ? 209  GLN H CD  1 
ATOM   2319 O OE1 . GLN B 2  221 ? -27.225 24.346  -46.598 1.00 12.26 ? 209  GLN H OE1 1 
ATOM   2320 N NE2 . GLN B 2  221 ? -27.634 22.489  -45.379 1.00 11.26 ? 209  GLN H NE2 1 
ATOM   2321 N N   . MET B 2  222 ? -32.489 22.289  -48.310 1.00 8.63  ? 210  MET H N   1 
ATOM   2322 C CA  . MET B 2  222 ? -33.677 21.889  -47.552 1.00 10.81 ? 210  MET H CA  1 
ATOM   2323 C C   . MET B 2  222 ? -33.319 21.152  -46.269 1.00 10.60 ? 210  MET H C   1 
ATOM   2324 O O   . MET B 2  222 ? -34.100 21.130  -45.313 1.00 11.07 ? 210  MET H O   1 
ATOM   2325 C CB  . MET B 2  222 ? -34.586 21.002  -48.418 1.00 10.76 ? 210  MET H CB  1 
ATOM   2326 C CG  . MET B 2  222 ? -34.979 21.627  -49.760 1.00 10.47 ? 210  MET H CG  1 
ATOM   2327 S SD  . MET B 2  222 ? -35.580 23.337  -49.601 1.00 15.96 ? 210  MET H SD  1 
ATOM   2328 C CE  . MET B 2  222 ? -37.082 23.070  -48.693 1.00 16.31 ? 210  MET H CE  1 
ATOM   2329 N N   . GLY B 2  223 ? -32.143 20.538  -46.245 1.00 8.70  ? 211  GLY H N   1 
ATOM   2330 C CA  . GLY B 2  223 ? -31.741 19.814  -45.055 1.00 8.97  ? 211  GLY H CA  1 
ATOM   2331 C C   . GLY B 2  223 ? -30.253 19.769  -44.793 1.00 7.70  ? 211  GLY H C   1 
ATOM   2332 O O   . GLY B 2  223 ? -29.448 20.191  -45.621 1.00 10.31 ? 211  GLY H O   1 
ATOM   2333 N N   . ILE B 2  224 ? -29.909 19.286  -43.606 1.00 8.04  ? 212  ILE H N   1 
ATOM   2334 C CA  . ILE B 2  224 ? -28.526 19.108  -43.175 1.00 9.50  ? 212  ILE H CA  1 
ATOM   2335 C C   . ILE B 2  224 ? -28.405 17.623  -42.859 1.00 10.33 ? 212  ILE H C   1 
ATOM   2336 O O   . ILE B 2  224 ? -29.256 17.075  -42.160 1.00 10.90 ? 212  ILE H O   1 
ATOM   2337 C CB  . ILE B 2  224 ? -28.221 19.889  -41.886 1.00 10.02 ? 212  ILE H CB  1 
ATOM   2338 C CG1 . ILE B 2  224 ? -28.424 21.383  -42.141 1.00 11.70 ? 212  ILE H CG1 1 
ATOM   2339 C CG2 . ILE B 2  224 ? -26.795 19.591  -41.422 1.00 12.11 ? 212  ILE H CG2 1 
ATOM   2340 C CD1 . ILE B 2  224 ? -28.435 22.231  -40.870 1.00 10.95 ? 212  ILE H CD1 1 
ATOM   2341 N N   . VAL B 2  225 ? -27.375 16.970  -43.386 1.00 10.62 ? 213  VAL H N   1 
ATOM   2342 C CA  . VAL B 2  225 ? -27.195 15.544  -43.107 1.00 11.45 ? 213  VAL H CA  1 
ATOM   2343 C C   . VAL B 2  225 ? -27.089 15.402  -41.591 1.00 11.39 ? 213  VAL H C   1 
ATOM   2344 O O   . VAL B 2  225 ? -26.213 15.990  -40.957 1.00 11.42 ? 213  VAL H O   1 
ATOM   2345 C CB  . VAL B 2  225 ? -25.906 14.982  -43.755 1.00 11.13 ? 213  VAL H CB  1 
ATOM   2346 C CG1 . VAL B 2  225 ? -25.718 13.524  -43.351 1.00 10.79 ? 213  VAL H CG1 1 
ATOM   2347 C CG2 . VAL B 2  225 ? -25.978 15.105  -45.275 1.00 11.12 ? 213  VAL H CG2 1 
ATOM   2348 N N   . SER B 2  226 ? -27.990 14.620  -41.015 1.00 11.27 ? 214  SER H N   1 
ATOM   2349 C CA  . SER B 2  226 ? -28.021 14.417  -39.584 1.00 11.20 ? 214  SER H CA  1 
ATOM   2350 C C   . SER B 2  226 ? -27.662 12.968  -39.264 1.00 14.85 ? 214  SER H C   1 
ATOM   2351 O O   . SER B 2  226 ? -26.646 12.461  -39.737 1.00 17.35 ? 214  SER H O   1 
ATOM   2352 C CB  . SER B 2  226 ? -29.413 14.780  -39.057 1.00 12.73 ? 214  SER H CB  1 
ATOM   2353 O OG  . SER B 2  226 ? -29.484 14.712  -37.651 1.00 12.74 ? 214  SER H OG  1 
ATOM   2354 N N   . TRP B 2  227 ? -28.492 12.301  -38.474 1.00 15.60 ? 215  TRP H N   1 
ATOM   2355 C CA  . TRP B 2  227 ? -28.205 10.922  -38.086 1.00 14.35 ? 215  TRP H CA  1 
ATOM   2356 C C   . TRP B 2  227 ? -28.819 9.841   -38.970 1.00 15.34 ? 215  TRP H C   1 
ATOM   2357 O O   . TRP B 2  227 ? -29.587 10.107  -39.897 1.00 14.77 ? 215  TRP H O   1 
ATOM   2358 C CB  . TRP B 2  227 ? -28.666 10.685  -36.649 1.00 15.23 ? 215  TRP H CB  1 
ATOM   2359 C CG  . TRP B 2  227 ? -30.132 10.906  -36.487 1.00 15.70 ? 215  TRP H CG  1 
ATOM   2360 C CD1 . TRP B 2  227 ? -30.771 12.103  -36.331 1.00 15.06 ? 215  TRP H CD1 1 
ATOM   2361 C CD2 . TRP B 2  227 ? -31.157 9.905   -36.504 1.00 15.44 ? 215  TRP H CD2 1 
ATOM   2362 N NE1 . TRP B 2  227 ? -32.128 11.912  -36.249 1.00 16.08 ? 215  TRP H NE1 1 
ATOM   2363 C CE2 . TRP B 2  227 ? -32.393 10.571  -36.352 1.00 15.51 ? 215  TRP H CE2 1 
ATOM   2364 C CE3 . TRP B 2  227 ? -31.150 8.510   -36.634 1.00 15.84 ? 215  TRP H CE3 1 
ATOM   2365 C CZ2 . TRP B 2  227 ? -33.612 9.894   -36.327 1.00 13.70 ? 215  TRP H CZ2 1 
ATOM   2366 C CZ3 . TRP B 2  227 ? -32.359 7.838   -36.610 1.00 12.74 ? 215  TRP H CZ3 1 
ATOM   2367 C CH2 . TRP B 2  227 ? -33.576 8.527   -36.457 1.00 14.79 ? 215  TRP H CH2 1 
ATOM   2368 N N   . GLY B 2  228 ? -28.459 8.605   -38.649 1.00 15.49 ? 216  GLY H N   1 
ATOM   2369 C CA  . GLY B 2  228 ? -28.979 7.460   -39.364 1.00 16.13 ? 216  GLY H CA  1 
ATOM   2370 C C   . GLY B 2  228 ? -28.735 6.263   -38.468 1.00 15.71 ? 216  GLY H C   1 
ATOM   2371 O O   . GLY B 2  228 ? -28.425 6.418   -37.290 1.00 16.39 ? 216  GLY H O   1 
ATOM   2372 N N   . GLU B 2  229 ? -28.895 5.069   -39.020 1.00 16.40 ? 217  GLU H N   1 
ATOM   2373 C CA  . GLU B 2  229 ? -28.644 3.839   -38.280 1.00 17.26 ? 217  GLU H CA  1 
ATOM   2374 C C   . GLU B 2  229 ? -27.898 2.999   -39.296 1.00 17.59 ? 217  GLU H C   1 
ATOM   2375 O O   . GLU B 2  229 ? -28.498 2.352   -40.154 1.00 18.64 ? 217  GLU H O   1 
ATOM   2376 C CB  . GLU B 2  229 ? -29.962 3.194   -37.847 1.00 15.69 ? 217  GLU H CB  1 
ATOM   2377 C CG  . GLU B 2  229 ? -30.580 3.880   -36.628 1.00 17.90 ? 217  GLU H CG  1 
ATOM   2378 C CD  . GLU B 2  229 ? -31.976 3.388   -36.318 1.00 18.30 ? 217  GLU H CD  1 
ATOM   2379 O OE1 . GLU B 2  229 ? -32.933 3.881   -36.940 1.00 16.86 ? 217  GLU H OE1 1 
ATOM   2380 O OE2 . GLU B 2  229 ? -32.115 2.495   -35.455 1.00 20.43 ? 217  GLU H OE2 1 
ATOM   2381 N N   . GLY B 2  230 ? -26.574 3.039   -39.205 1.00 17.12 ? 219  GLY H N   1 
ATOM   2382 C CA  . GLY B 2  230 ? -25.760 2.339   -40.175 1.00 17.18 ? 219  GLY H CA  1 
ATOM   2383 C C   . GLY B 2  230 ? -25.847 3.188   -41.431 1.00 17.50 ? 219  GLY H C   1 
ATOM   2384 O O   . GLY B 2  230 ? -26.185 4.375   -41.350 1.00 18.79 ? 219  GLY H O   1 
ATOM   2385 N N   . CYS B 2  231 ? -25.552 2.601   -42.584 1.00 16.76 ? 220  CYS H N   1 
ATOM   2386 C CA  . CYS B 2  231 ? -25.618 3.325   -43.850 1.00 16.75 ? 220  CYS H CA  1 
ATOM   2387 C C   . CYS B 2  231 ? -26.154 2.425   -44.949 1.00 17.71 ? 220  CYS H C   1 
ATOM   2388 O O   . CYS B 2  231 ? -25.713 1.283   -45.092 1.00 19.47 ? 220  CYS H O   1 
ATOM   2389 C CB  . CYS B 2  231 ? -24.233 3.815   -44.267 1.00 16.93 ? 220  CYS H CB  1 
ATOM   2390 S SG  . CYS B 2  231 ? -23.401 4.844   -43.027 1.00 19.24 ? 220  CYS H SG  1 
ATOM   2391 N N   . ASP B 2  232 ? -27.104 2.955   -45.716 1.00 16.83 ? 221  ASP H N   1 
ATOM   2392 C CA  . ASP B 2  232 ? -27.715 2.253   -46.835 1.00 18.07 ? 221  ASP H CA  1 
ATOM   2393 C C   . ASP B 2  232 ? -28.293 0.883   -46.478 1.00 19.91 ? 221  ASP H C   1 
ATOM   2394 O O   . ASP B 2  232 ? -28.290 -0.025  -47.311 1.00 20.05 ? 221  ASP H O   1 
ATOM   2395 C CB  . ASP B 2  232 ? -26.691 2.112   -47.976 1.00 20.07 ? 221  ASP H CB  1 
ATOM   2396 C CG  . ASP B 2  232 ? -27.344 1.825   -49.321 1.00 22.78 ? 221  ASP H CG  1 
ATOM   2397 O OD1 . ASP B 2  232 ? -28.263 2.576   -49.718 1.00 21.69 ? 221  ASP H OD1 1 
ATOM   2398 O OD2 . ASP B 2  232 ? -26.932 0.852   -49.989 1.00 21.89 ? 221  ASP H OD2 1 
ATOM   2399 N N   . ARG B 2  233 A -28.794 0.736   -45.253 1.00 18.11 ? 221  ARG H N   1 
ATOM   2400 C CA  . ARG B 2  233 A -29.392 -0.537  -44.828 1.00 18.80 ? 221  ARG H CA  1 
ATOM   2401 C C   . ARG B 2  233 A -30.797 -0.665  -45.410 1.00 19.20 ? 221  ARG H C   1 
ATOM   2402 O O   . ARG B 2  233 A -31.481 0.336   -45.627 1.00 17.02 ? 221  ARG H O   1 
ATOM   2403 C CB  . ARG B 2  233 A -29.470 -0.617  -43.304 1.00 18.37 ? 221  ARG H CB  1 
ATOM   2404 C CG  . ARG B 2  233 A -28.123 -0.692  -42.601 1.00 19.40 ? 221  ARG H CG  1 
ATOM   2405 C CD  . ARG B 2  233 A -28.308 -0.799  -41.095 1.00 19.99 ? 221  ARG H CD  1 
ATOM   2406 N NE  . ARG B 2  233 A -27.035 -0.832  -40.379 1.00 21.99 ? 221  ARG H NE  1 
ATOM   2407 C CZ  . ARG B 2  233 A -26.918 -0.714  -39.060 1.00 24.24 ? 221  ARG H CZ  1 
ATOM   2408 N NH1 . ARG B 2  233 A -27.998 -0.556  -38.303 1.00 27.10 ? 221  ARG H NH1 1 
ATOM   2409 N NH2 . ARG B 2  233 A -25.717 -0.736  -38.496 1.00 26.52 ? 221  ARG H NH2 1 
ATOM   2410 N N   A ASP B 2  234 ? -31.222 -1.891  -45.689 0.10 18.51 ? 222  ASP H N   1 
ATOM   2411 N N   B ASP B 2  234 ? -31.228 -1.908  -45.642 0.77 16.87 ? 222  ASP H N   1 
ATOM   2412 C CA  A ASP B 2  234 ? -32.546 -2.097  -46.255 0.69 18.95 ? 222  ASP H CA  1 
ATOM   2413 C CA  B ASP B 2  234 ? -32.553 -2.170  -46.194 0.10 17.34 ? 222  ASP H CA  1 
ATOM   2414 C C   A ASP B 2  234 ? -33.636 -1.693  -45.273 0.21 17.86 ? 222  ASP H C   1 
ATOM   2415 C C   B ASP B 2  234 ? -33.645 -1.692  -45.243 0.79 15.91 ? 222  ASP H C   1 
ATOM   2416 O O   A ASP B 2  234 ? -33.584 -2.028  -44.089 0.10 17.92 ? 222  ASP H O   1 
ATOM   2417 O O   B ASP B 2  234 ? -33.596 -1.971  -44.041 0.74 14.87 ? 222  ASP H O   1 
ATOM   2418 C CB  A ASP B 2  234 ? -32.730 -3.561  -46.665 0.14 19.41 ? 222  ASP H CB  1 
ATOM   2419 C CB  B ASP B 2  234 ? -32.761 -3.672  -46.442 0.40 18.10 ? 222  ASP H CB  1 
ATOM   2420 C CG  A ASP B 2  234 ? -31.798 -3.971  -47.787 0.39 20.08 ? 222  ASP H CG  1 
ATOM   2421 C CG  B ASP B 2  234 ? -31.550 -4.344  -47.052 0.26 18.88 ? 222  ASP H CG  1 
ATOM   2422 O OD1 A ASP B 2  234 ? -31.780 -3.277  -48.826 0.35 20.23 ? 222  ASP H OD1 1 
ATOM   2423 O OD1 B ASP B 2  234 ? -30.866 -3.700  -47.874 0.38 17.99 ? 222  ASP H OD1 1 
ATOM   2424 O OD2 A ASP B 2  234 ? -31.088 -4.987  -47.633 0.10 21.06 ? 222  ASP H OD2 1 
ATOM   2425 O OD2 B ASP B 2  234 ? -31.295 -5.527  -46.718 0.72 21.48 ? 222  ASP H OD2 1 
ATOM   2426 N N   . GLY B 2  235 ? -34.623 -0.965  -45.781 1.00 17.96 ? 223  GLY H N   1 
ATOM   2427 C CA  . GLY B 2  235 ? -35.724 -0.505  -44.956 1.00 14.90 ? 223  GLY H CA  1 
ATOM   2428 C C   . GLY B 2  235 ? -35.393 0.594   -43.961 1.00 15.13 ? 223  GLY H C   1 
ATOM   2429 O O   . GLY B 2  235 ? -36.176 0.861   -43.051 1.00 14.85 ? 223  GLY H O   1 
ATOM   2430 N N   . LYS B 2  236 ? -34.231 1.217   -44.119 1.00 14.33 ? 224  LYS H N   1 
ATOM   2431 C CA  . LYS B 2  236 ? -33.831 2.306   -43.229 1.00 13.08 ? 224  LYS H CA  1 
ATOM   2432 C C   . LYS B 2  236 ? -33.658 3.538   -44.098 1.00 13.31 ? 224  LYS H C   1 
ATOM   2433 O O   . LYS B 2  236 ? -33.501 3.424   -45.311 1.00 13.73 ? 224  LYS H O   1 
ATOM   2434 C CB  . LYS B 2  236 ? -32.509 1.983   -42.524 1.00 14.27 ? 224  LYS H CB  1 
ATOM   2435 C CG  . LYS B 2  236 ? -32.527 0.686   -41.707 1.00 15.28 ? 224  LYS H CG  1 
ATOM   2436 C CD  . LYS B 2  236 ? -33.510 0.739   -40.535 1.00 14.51 ? 224  LYS H CD  1 
ATOM   2437 C CE  . LYS B 2  236 ? -33.033 1.679   -39.425 1.00 14.19 ? 224  LYS H CE  1 
ATOM   2438 N NZ  . LYS B 2  236 ? -33.910 1.627   -38.215 1.00 15.10 ? 224  LYS H NZ  1 
ATOM   2439 N N   . TYR B 2  237 ? -33.694 4.714   -43.478 1.00 12.20 ? 225  TYR H N   1 
ATOM   2440 C CA  . TYR B 2  237 ? -33.541 5.954   -44.224 1.00 13.16 ? 225  TYR H CA  1 
ATOM   2441 C C   . TYR B 2  237 ? -32.657 6.915   -43.465 1.00 12.95 ? 225  TYR H C   1 
ATOM   2442 O O   . TYR B 2  237 ? -32.586 6.868   -42.234 1.00 13.78 ? 225  TYR H O   1 
ATOM   2443 C CB  . TYR B 2  237 ? -34.904 6.612   -44.463 1.00 12.37 ? 225  TYR H CB  1 
ATOM   2444 C CG  . TYR B 2  237 ? -35.881 5.679   -45.125 1.00 12.49 ? 225  TYR H CG  1 
ATOM   2445 C CD1 . TYR B 2  237 ? -36.720 4.867   -44.364 1.00 14.92 ? 225  TYR H CD1 1 
ATOM   2446 C CD2 . TYR B 2  237 ? -35.922 5.559   -46.513 1.00 14.32 ? 225  TYR H CD2 1 
ATOM   2447 C CE1 . TYR B 2  237 ? -37.572 3.955   -44.974 1.00 16.50 ? 225  TYR H CE1 1 
ATOM   2448 C CE2 . TYR B 2  237 ? -36.764 4.656   -47.130 1.00 14.71 ? 225  TYR H CE2 1 
ATOM   2449 C CZ  . TYR B 2  237 ? -37.586 3.854   -46.358 1.00 17.83 ? 225  TYR H CZ  1 
ATOM   2450 O OH  . TYR B 2  237 ? -38.408 2.936   -46.966 1.00 19.86 ? 225  TYR H OH  1 
ATOM   2451 N N   . GLY B 2  238 ? -31.973 7.775   -44.208 1.00 12.41 ? 226  GLY H N   1 
ATOM   2452 C CA  . GLY B 2  238 ? -31.119 8.755   -43.573 1.00 12.00 ? 226  GLY H CA  1 
ATOM   2453 C C   . GLY B 2  238 ? -31.997 9.893   -43.100 1.00 12.74 ? 226  GLY H C   1 
ATOM   2454 O O   . GLY B 2  238 ? -33.022 10.184  -43.722 1.00 10.78 ? 226  GLY H O   1 
ATOM   2455 N N   . PHE B 2  239 ? -31.618 10.524  -41.992 1.00 12.88 ? 227  PHE H N   1 
ATOM   2456 C CA  . PHE B 2  239 ? -32.395 11.636  -41.481 1.00 12.38 ? 227  PHE H CA  1 
ATOM   2457 C C   . PHE B 2  239 ? -31.668 12.945  -41.663 1.00 12.29 ? 227  PHE H C   1 
ATOM   2458 O O   . PHE B 2  239 ? -30.437 12.998  -41.649 1.00 11.02 ? 227  PHE H O   1 
ATOM   2459 C CB  . PHE B 2  239 ? -32.790 11.390  -40.029 1.00 14.06 ? 227  PHE H CB  1 
ATOM   2460 C CG  . PHE B 2  239 ? -33.927 10.416  -39.893 1.00 14.08 ? 227  PHE H CG  1 
ATOM   2461 C CD1 . PHE B 2  239 ? -33.724 9.053   -40.112 1.00 14.52 ? 227  PHE H CD1 1 
ATOM   2462 C CD2 . PHE B 2  239 ? -35.216 10.866  -39.628 1.00 14.36 ? 227  PHE H CD2 1 
ATOM   2463 C CE1 . PHE B 2  239 ? -34.792 8.165   -40.068 1.00 15.83 ? 227  PHE H CE1 1 
ATOM   2464 C CE2 . PHE B 2  239 ? -36.292 9.982   -39.585 1.00 15.22 ? 227  PHE H CE2 1 
ATOM   2465 C CZ  . PHE B 2  239 ? -36.078 8.629   -39.805 1.00 15.29 ? 227  PHE H CZ  1 
ATOM   2466 N N   . TYR B 2  240 ? -32.455 13.998  -41.851 1.00 10.23 ? 228  TYR H N   1 
ATOM   2467 C CA  . TYR B 2  240 ? -31.911 15.320  -42.127 1.00 10.24 ? 228  TYR H CA  1 
ATOM   2468 C C   . TYR B 2  240 ? -32.601 16.372  -41.299 1.00 10.97 ? 228  TYR H C   1 
ATOM   2469 O O   . TYR B 2  240 ? -33.786 16.258  -41.006 1.00 12.25 ? 228  TYR H O   1 
ATOM   2470 C CB  . TYR B 2  240 ? -32.109 15.653  -43.609 1.00 8.38  ? 228  TYR H CB  1 
ATOM   2471 C CG  . TYR B 2  240 ? -31.470 14.648  -44.540 1.00 9.10  ? 228  TYR H CG  1 
ATOM   2472 C CD1 . TYR B 2  240 ? -32.065 13.414  -44.784 1.00 11.45 ? 228  TYR H CD1 1 
ATOM   2473 C CD2 . TYR B 2  240 ? -30.218 14.896  -45.093 1.00 10.44 ? 228  TYR H CD2 1 
ATOM   2474 C CE1 . TYR B 2  240 ? -31.414 12.442  -45.549 1.00 11.47 ? 228  TYR H CE1 1 
ATOM   2475 C CE2 . TYR B 2  240 ? -29.563 13.938  -45.860 1.00 11.18 ? 228  TYR H CE2 1 
ATOM   2476 C CZ  . TYR B 2  240 ? -30.162 12.713  -46.077 1.00 12.87 ? 228  TYR H CZ  1 
ATOM   2477 O OH  . TYR B 2  240 ? -29.482 11.746  -46.789 1.00 14.36 ? 228  TYR H OH  1 
ATOM   2478 N N   . THR B 2  241 ? -31.844 17.400  -40.925 1.00 9.66  ? 229  THR H N   1 
ATOM   2479 C CA  . THR B 2  241 ? -32.400 18.505  -40.160 1.00 11.97 ? 229  THR H CA  1 
ATOM   2480 C C   . THR B 2  241 ? -33.232 19.331  -41.133 1.00 10.78 ? 229  THR H C   1 
ATOM   2481 O O   . THR B 2  241 ? -32.778 19.675  -42.227 1.00 11.38 ? 229  THR H O   1 
ATOM   2482 C CB  . THR B 2  241 ? -31.290 19.373  -39.582 1.00 10.38 ? 229  THR H CB  1 
ATOM   2483 O OG1 . THR B 2  241 ? -30.406 18.553  -38.815 1.00 11.19 ? 229  THR H OG1 1 
ATOM   2484 C CG2 . THR B 2  241 ? -31.867 20.450  -38.693 1.00 11.97 ? 229  THR H CG2 1 
ATOM   2485 N N   . HIS B 2  242 ? -34.460 19.633  -40.727 1.00 10.58 ? 230  HIS H N   1 
ATOM   2486 C CA  . HIS B 2  242 ? -35.409 20.386  -41.540 1.00 10.37 ? 230  HIS H CA  1 
ATOM   2487 C C   . HIS B 2  242 ? -35.015 21.859  -41.475 1.00 12.22 ? 230  HIS H C   1 
ATOM   2488 O O   . HIS B 2  242 ? -35.393 22.561  -40.548 1.00 12.57 ? 230  HIS H O   1 
ATOM   2489 C CB  . HIS B 2  242 ? -36.805 20.172  -40.952 1.00 14.17 ? 230  HIS H CB  1 
ATOM   2490 C CG  . HIS B 2  242 ? -37.923 20.510  -41.885 1.00 14.76 ? 230  HIS H CG  1 
ATOM   2491 N ND1 . HIS B 2  242 ? -38.043 21.740  -42.495 1.00 13.84 ? 230  HIS H ND1 1 
ATOM   2492 C CD2 . HIS B 2  242 ? -39.006 19.792  -42.266 1.00 13.82 ? 230  HIS H CD2 1 
ATOM   2493 C CE1 . HIS B 2  242 ? -39.155 21.765  -43.210 1.00 14.55 ? 230  HIS H CE1 1 
ATOM   2494 N NE2 . HIS B 2  242 ? -39.756 20.593  -43.089 1.00 14.90 ? 230  HIS H NE2 1 
ATOM   2495 N N   . VAL B 2  243 ? -34.254 22.319  -42.462 1.00 11.16 ? 231  VAL H N   1 
ATOM   2496 C CA  . VAL B 2  243 ? -33.764 23.699  -42.465 1.00 12.18 ? 231  VAL H CA  1 
ATOM   2497 C C   . VAL B 2  243 ? -34.835 24.776  -42.369 1.00 12.06 ? 231  VAL H C   1 
ATOM   2498 O O   . VAL B 2  243 ? -34.690 25.730  -41.596 1.00 14.72 ? 231  VAL H O   1 
ATOM   2499 C CB  . VAL B 2  243 ? -32.880 23.961  -43.715 1.00 11.53 ? 231  VAL H CB  1 
ATOM   2500 C CG1 . VAL B 2  243 ? -32.510 25.441  -43.813 1.00 12.11 ? 231  VAL H CG1 1 
ATOM   2501 C CG2 . VAL B 2  243 ? -31.603 23.121  -43.616 1.00 12.39 ? 231  VAL H CG2 1 
ATOM   2502 N N   . PHE B 2  244 ? -35.902 24.654  -43.146 1.00 11.59 ? 232  PHE H N   1 
ATOM   2503 C CA  . PHE B 2  244 ? -36.930 25.675  -43.075 1.00 13.63 ? 232  PHE H CA  1 
ATOM   2504 C C   . PHE B 2  244 ? -37.552 25.795  -41.688 1.00 13.73 ? 232  PHE H C   1 
ATOM   2505 O O   . PHE B 2  244 ? -37.823 26.902  -41.211 1.00 13.70 ? 232  PHE H O   1 
ATOM   2506 C CB  . PHE B 2  244 ? -38.047 25.427  -44.079 1.00 13.34 ? 232  PHE H CB  1 
ATOM   2507 C CG  . PHE B 2  244 ? -39.105 26.479  -44.032 1.00 14.45 ? 232  PHE H CG  1 
ATOM   2508 C CD1 . PHE B 2  244 ? -38.803 27.791  -44.382 1.00 18.05 ? 232  PHE H CD1 1 
ATOM   2509 C CD2 . PHE B 2  244 ? -40.372 26.188  -43.540 1.00 17.48 ? 232  PHE H CD2 1 
ATOM   2510 C CE1 . PHE B 2  244 ? -39.749 28.805  -44.238 1.00 18.41 ? 232  PHE H CE1 1 
ATOM   2511 C CE2 . PHE B 2  244 ? -41.317 27.190  -43.391 1.00 18.38 ? 232  PHE H CE2 1 
ATOM   2512 C CZ  . PHE B 2  244 ? -41.007 28.502  -43.739 1.00 18.33 ? 232  PHE H CZ  1 
ATOM   2513 N N   . ARG B 2  245 ? -37.806 24.671  -41.038 1.00 13.09 ? 233  ARG H N   1 
ATOM   2514 C CA  . ARG B 2  245 ? -38.417 24.748  -39.719 1.00 14.11 ? 233  ARG H CA  1 
ATOM   2515 C C   . ARG B 2  245 ? -37.540 25.393  -38.656 1.00 15.68 ? 233  ARG H C   1 
ATOM   2516 O O   . ARG B 2  245 ? -38.031 25.789  -37.597 1.00 18.00 ? 233  ARG H O   1 
ATOM   2517 C CB  . ARG B 2  245 ? -38.905 23.364  -39.288 1.00 17.10 ? 233  ARG H CB  1 
ATOM   2518 C CG  . ARG B 2  245 ? -40.250 23.068  -39.935 1.00 21.87 ? 233  ARG H CG  1 
ATOM   2519 C CD  . ARG B 2  245 ? -40.784 21.685  -39.680 1.00 26.43 ? 233  ARG H CD  1 
ATOM   2520 N NE  . ARG B 2  245 ? -42.094 21.537  -40.311 1.00 29.35 ? 233  ARG H NE  1 
ATOM   2521 C CZ  . ARG B 2  245 ? -42.645 20.375  -40.641 1.00 30.84 ? 233  ARG H CZ  1 
ATOM   2522 N NH1 . ARG B 2  245 ? -43.843 20.353  -41.210 1.00 32.72 ? 233  ARG H NH1 1 
ATOM   2523 N NH2 . ARG B 2  245 ? -41.997 19.239  -40.414 1.00 30.11 ? 233  ARG H NH2 1 
ATOM   2524 N N   A LEU B 2  246 ? -36.247 25.508  -38.945 0.25 15.49 ? 234  LEU H N   1 
ATOM   2525 N N   B LEU B 2  246 ? -36.248 25.522  -38.942 0.75 15.01 ? 234  LEU H N   1 
ATOM   2526 C CA  A LEU B 2  246 ? -35.304 26.117  -38.014 0.21 15.31 ? 234  LEU H CA  1 
ATOM   2527 C CA  B LEU B 2  246 ? -35.333 26.132  -37.989 0.71 14.87 ? 234  LEU H CA  1 
ATOM   2528 C C   A LEU B 2  246 ? -34.802 27.459  -38.539 0.10 15.05 ? 234  LEU H C   1 
ATOM   2529 C C   B LEU B 2  246 ? -34.836 27.486  -38.502 0.90 14.11 ? 234  LEU H C   1 
ATOM   2530 O O   A LEU B 2  246 ? -33.828 28.011  -38.026 0.14 14.67 ? 234  LEU H O   1 
ATOM   2531 O O   B LEU B 2  246 ? -33.901 28.068  -37.948 0.66 12.76 ? 234  LEU H O   1 
ATOM   2532 C CB  A LEU B 2  246 ? -34.117 25.180  -37.775 0.25 15.99 ? 234  LEU H CB  1 
ATOM   2533 C CB  B LEU B 2  246 ? -34.154 25.184  -37.728 0.54 16.77 ? 234  LEU H CB  1 
ATOM   2534 C CG  A LEU B 2  246 ? -34.411 23.902  -36.984 0.12 16.30 ? 234  LEU H CG  1 
ATOM   2535 C CG  B LEU B 2  246 ? -34.547 23.776  -37.251 0.88 17.74 ? 234  LEU H CG  1 
ATOM   2536 C CD1 A LEU B 2  246 ? -33.176 23.021  -36.953 0.10 16.62 ? 234  LEU H CD1 1 
ATOM   2537 C CD1 B LEU B 2  246 ? -33.304 22.982  -36.904 0.51 18.55 ? 234  LEU H CD1 1 
ATOM   2538 C CD2 A LEU B 2  246 ? -34.847 24.263  -35.570 0.26 16.70 ? 234  LEU H CD2 1 
ATOM   2539 C CD2 B LEU B 2  246 ? -35.465 23.875  -36.043 0.26 18.25 ? 234  LEU H CD2 1 
ATOM   2540 N N   . LYS B 2  247 ? -35.474 27.980  -39.560 1.00 14.77 ? 235  LYS H N   1 
ATOM   2541 C CA  . LYS B 2  247 ? -35.091 29.255  -40.156 1.00 14.92 ? 235  LYS H CA  1 
ATOM   2542 C C   . LYS B 2  247 ? -35.228 30.433  -39.195 1.00 16.94 ? 235  LYS H C   1 
ATOM   2543 O O   . LYS B 2  247 ? -34.423 31.367  -39.241 1.00 13.57 ? 235  LYS H O   1 
ATOM   2544 C CB  . LYS B 2  247 ? -35.902 29.517  -41.424 1.00 14.71 ? 235  LYS H CB  1 
ATOM   2545 C CG  . LYS B 2  247 ? -35.341 30.657  -42.272 1.00 16.00 ? 235  LYS H CG  1 
ATOM   2546 C CD  . LYS B 2  247 ? -36.069 30.795  -43.592 1.00 16.36 ? 235  LYS H CD  1 
ATOM   2547 C CE  . LYS B 2  247 ? -35.301 31.706  -44.536 1.00 17.97 ? 235  LYS H CE  1 
ATOM   2548 N NZ  . LYS B 2  247 ? -36.028 31.903  -45.816 1.00 20.58 ? 235  LYS H NZ  1 
ATOM   2549 N N   . LYS B 2  248 ? -36.240 30.402  -38.332 1.00 17.48 ? 236  LYS H N   1 
ATOM   2550 C CA  . LYS B 2  248 ? -36.408 31.484  -37.367 1.00 19.10 ? 236  LYS H CA  1 
ATOM   2551 C C   . LYS B 2  248 ? -35.207 31.535  -36.431 1.00 18.03 ? 236  LYS H C   1 
ATOM   2552 O O   . LYS B 2  248 ? -34.733 32.616  -36.080 1.00 18.38 ? 236  LYS H O   1 
ATOM   2553 C CB  . LYS B 2  248 ? -37.701 31.303  -36.567 1.00 20.37 ? 236  LYS H CB  1 
ATOM   2554 C CG  . LYS B 2  248 ? -38.953 31.583  -37.377 1.00 23.41 ? 236  LYS H CG  1 
ATOM   2555 N N   . TRP B 2  249 ? -34.703 30.367  -36.039 1.00 16.36 ? 237  TRP H N   1 
ATOM   2556 C CA  . TRP B 2  249 ? -33.540 30.296  -35.166 1.00 16.72 ? 237  TRP H CA  1 
ATOM   2557 C C   . TRP B 2  249 ? -32.319 30.823  -35.923 1.00 16.18 ? 237  TRP H C   1 
ATOM   2558 O O   . TRP B 2  249 ? -31.526 31.590  -35.380 1.00 17.83 ? 237  TRP H O   1 
ATOM   2559 C CB  . TRP B 2  249 ? -33.279 28.854  -34.726 1.00 16.50 ? 237  TRP H CB  1 
ATOM   2560 C CG  . TRP B 2  249 ? -32.006 28.707  -33.955 1.00 15.57 ? 237  TRP H CG  1 
ATOM   2561 C CD1 . TRP B 2  249 ? -31.793 29.024  -32.638 1.00 16.87 ? 237  TRP H CD1 1 
ATOM   2562 C CD2 . TRP B 2  249 ? -30.749 28.259  -34.468 1.00 14.92 ? 237  TRP H CD2 1 
ATOM   2563 N NE1 . TRP B 2  249 ? -30.482 28.799  -32.305 1.00 16.95 ? 237  TRP H NE1 1 
ATOM   2564 C CE2 . TRP B 2  249 ? -29.817 28.332  -33.410 1.00 16.30 ? 237  TRP H CE2 1 
ATOM   2565 C CE3 . TRP B 2  249 ? -30.318 27.807  -35.724 1.00 14.12 ? 237  TRP H CE3 1 
ATOM   2566 C CZ2 . TRP B 2  249 ? -28.476 27.969  -33.567 1.00 16.15 ? 237  TRP H CZ2 1 
ATOM   2567 C CZ3 . TRP B 2  249 ? -28.986 27.449  -35.880 1.00 14.08 ? 237  TRP H CZ3 1 
ATOM   2568 C CH2 . TRP B 2  249 ? -28.081 27.532  -34.808 1.00 16.25 ? 237  TRP H CH2 1 
ATOM   2569 N N   . ILE B 2  250 ? -32.164 30.394  -37.174 1.00 14.96 ? 238  ILE H N   1 
ATOM   2570 C CA  . ILE B 2  250 ? -31.049 30.846  -38.004 1.00 13.64 ? 238  ILE H CA  1 
ATOM   2571 C C   . ILE B 2  250 ? -31.062 32.377  -38.080 1.00 13.16 ? 238  ILE H C   1 
ATOM   2572 O O   . ILE B 2  250 ? -30.037 33.028  -37.879 1.00 14.86 ? 238  ILE H O   1 
ATOM   2573 C CB  . ILE B 2  250 ? -31.153 30.248  -39.422 1.00 14.39 ? 238  ILE H CB  1 
ATOM   2574 C CG1 . ILE B 2  250 ? -30.863 28.744  -39.354 1.00 13.49 ? 238  ILE H CG1 1 
ATOM   2575 C CG2 . ILE B 2  250 ? -30.206 30.965  -40.384 1.00 15.47 ? 238  ILE H CG2 1 
ATOM   2576 C CD1 . ILE B 2  250 ? -31.057 28.023  -40.665 1.00 13.45 ? 238  ILE H CD1 1 
ATOM   2577 N N   . GLN B 2  251 ? -32.234 32.939  -38.361 1.00 13.97 ? 239  GLN H N   1 
ATOM   2578 C CA  . GLN B 2  251 ? -32.383 34.394  -38.451 1.00 15.76 ? 239  GLN H CA  1 
ATOM   2579 C C   . GLN B 2  251 ? -31.977 35.086  -37.152 1.00 16.52 ? 239  GLN H C   1 
ATOM   2580 O O   . GLN B 2  251 ? -31.263 36.098  -37.169 1.00 16.53 ? 239  GLN H O   1 
ATOM   2581 C CB  . GLN B 2  251 ? -33.833 34.742  -38.774 1.00 14.99 ? 239  GLN H CB  1 
ATOM   2582 C CG  . GLN B 2  251 ? -34.124 36.228  -38.840 1.00 20.99 ? 239  GLN H CG  1 
ATOM   2583 C CD  . GLN B 2  251 ? -35.556 36.504  -39.239 1.00 21.21 ? 239  GLN H CD  1 
ATOM   2584 O OE1 . GLN B 2  251 ? -36.487 35.906  -38.696 1.00 24.99 ? 239  GLN H OE1 1 
ATOM   2585 N NE2 . GLN B 2  251 ? -35.745 37.414  -40.189 1.00 24.14 ? 239  GLN H NE2 1 
ATOM   2586 N N   A LYS B 2  252 ? -32.431 34.556  -36.020 0.10 15.83 ? 240  LYS H N   1 
ATOM   2587 N N   B LYS B 2  252 ? -32.439 34.537  -36.034 0.90 16.21 ? 240  LYS H N   1 
ATOM   2588 C CA  A LYS B 2  252 ? -32.103 35.151  -34.726 0.10 15.33 ? 240  LYS H CA  1 
ATOM   2589 C CA  B LYS B 2  252 ? -32.135 35.086  -34.716 0.84 15.80 ? 240  LYS H CA  1 
ATOM   2590 C C   A LYS B 2  252 ? -30.606 35.129  -34.438 0.11 15.06 ? 240  LYS H C   1 
ATOM   2591 C C   B LYS B 2  252 ? -30.634 35.110  -34.427 0.62 15.59 ? 240  LYS H C   1 
ATOM   2592 O O   A LYS B 2  252 ? -30.039 36.125  -33.986 0.34 14.36 ? 240  LYS H O   1 
ATOM   2593 O O   B LYS B 2  252 ? -30.095 36.118  -33.969 0.36 14.72 ? 240  LYS H O   1 
ATOM   2594 C CB  A LYS B 2  252 ? -32.852 34.433  -33.601 0.60 15.46 ? 240  LYS H CB  1 
ATOM   2595 C CB  B LYS B 2  252 ? -32.851 34.269  -33.639 0.17 16.11 ? 240  LYS H CB  1 
ATOM   2596 C CG  A LYS B 2  252 ? -34.360 34.599  -33.654 0.34 15.07 ? 240  LYS H CG  1 
ATOM   2597 C CG  B LYS B 2  252 ? -32.536 34.703  -32.223 0.51 16.34 ? 240  LYS H CG  1 
ATOM   2598 N N   . VAL B 2  253 ? -29.966 33.992  -34.693 1.00 14.86 ? 241  VAL H N   1 
ATOM   2599 C CA  . VAL B 2  253 ? -28.535 33.872  -34.458 1.00 14.79 ? 241  VAL H CA  1 
ATOM   2600 C C   . VAL B 2  253 ? -27.758 34.840  -35.340 1.00 17.31 ? 241  VAL H C   1 
ATOM   2601 O O   . VAL B 2  253 ? -26.848 35.530  -34.878 1.00 17.85 ? 241  VAL H O   1 
ATOM   2602 C CB  . VAL B 2  253 ? -28.048 32.434  -34.730 1.00 16.52 ? 241  VAL H CB  1 
ATOM   2603 C CG1 . VAL B 2  253 ? -26.521 32.387  -34.736 1.00 16.73 ? 241  VAL H CG1 1 
ATOM   2604 C CG2 . VAL B 2  253 ? -28.610 31.501  -33.672 1.00 15.91 ? 241  VAL H CG2 1 
ATOM   2605 N N   . ILE B 2  254 ? -28.126 34.901  -36.614 1.00 16.12 ? 242  ILE H N   1 
ATOM   2606 C CA  . ILE B 2  254 ? -27.438 35.791  -37.532 1.00 16.72 ? 242  ILE H CA  1 
ATOM   2607 C C   . ILE B 2  254 ? -27.629 37.244  -37.116 1.00 16.71 ? 242  ILE H C   1 
ATOM   2608 O O   . ILE B 2  254 ? -26.694 38.034  -37.172 1.00 17.67 ? 242  ILE H O   1 
ATOM   2609 C CB  . ILE B 2  254 ? -27.922 35.558  -38.976 1.00 17.62 ? 242  ILE H CB  1 
ATOM   2610 C CG1 . ILE B 2  254 ? -27.415 34.184  -39.440 1.00 18.41 ? 242  ILE H CG1 1 
ATOM   2611 C CG2 . ILE B 2  254 ? -27.411 36.663  -39.906 1.00 17.05 ? 242  ILE H CG2 1 
ATOM   2612 C CD1 . ILE B 2  254 ? -27.874 33.770  -40.811 1.00 19.98 ? 242  ILE H CD1 1 
ATOM   2613 N N   A ASP B 2  255 ? -28.834 37.594  -36.677 0.13 17.45 ? 243  ASP H N   1 
ATOM   2614 N N   B ASP B 2  255 ? -28.843 37.583  -36.701 0.87 16.66 ? 243  ASP H N   1 
ATOM   2615 C CA  A ASP B 2  255 ? -29.112 38.965  -36.252 0.34 17.75 ? 243  ASP H CA  1 
ATOM   2616 C CA  B ASP B 2  255 ? -29.124 38.951  -36.284 0.66 16.49 ? 243  ASP H CA  1 
ATOM   2617 C C   A ASP B 2  255 ? -28.246 39.393  -35.071 0.17 18.11 ? 243  ASP H C   1 
ATOM   2618 C C   B ASP B 2  255 ? -28.342 39.352  -35.036 0.67 16.83 ? 243  ASP H C   1 
ATOM   2619 O O   A ASP B 2  255 ? -27.662 40.478  -35.077 0.46 17.72 ? 243  ASP H O   1 
ATOM   2620 O O   B ASP B 2  255 ? -27.909 40.499  -34.913 0.47 16.08 ? 243  ASP H O   1 
ATOM   2621 C CB  A ASP B 2  255 ? -30.584 39.124  -35.856 0.19 18.16 ? 243  ASP H CB  1 
ATOM   2622 C CB  B ASP B 2  255 ? -30.617 39.123  -36.013 0.66 16.35 ? 243  ASP H CB  1 
ATOM   2623 C CG  A ASP B 2  255 ? -31.526 38.918  -37.018 0.38 18.54 ? 243  ASP H CG  1 
ATOM   2624 C CG  B ASP B 2  255 ? -30.958 40.515  -35.533 0.53 16.52 ? 243  ASP H CG  1 
ATOM   2625 O OD1 A ASP B 2  255 ? -31.237 39.446  -38.108 0.21 19.08 ? 243  ASP H OD1 1 
ATOM   2626 O OD1 B ASP B 2  255 ? -30.683 41.474  -36.281 0.63 16.32 ? 243  ASP H OD1 1 
ATOM   2627 O OD2 A ASP B 2  255 ? -32.558 38.239  -36.841 0.10 19.15 ? 243  ASP H OD2 1 
ATOM   2628 O OD2 B ASP B 2  255 ? -31.492 40.644  -34.412 0.49 16.52 ? 243  ASP H OD2 1 
ATOM   2629 N N   A GLN B 2  256 ? -28.168 38.535  -34.060 0.10 18.60 ? 244  GLN H N   1 
ATOM   2630 N N   B GLN B 2  256 ? -28.157 38.412  -34.114 0.83 17.55 ? 244  GLN H N   1 
ATOM   2631 C CA  A GLN B 2  256 ? -27.403 38.833  -32.856 0.32 19.15 ? 244  GLN H CA  1 
ATOM   2632 C CA  B GLN B 2  256 ? -27.449 38.701  -32.868 0.62 18.76 ? 244  GLN H CA  1 
ATOM   2633 C C   A GLN B 2  256 ? -25.886 38.760  -32.982 0.28 18.92 ? 244  GLN H C   1 
ATOM   2634 C C   B GLN B 2  256 ? -25.928 38.719  -32.968 0.54 18.73 ? 244  GLN H C   1 
ATOM   2635 O O   A GLN B 2  256 ? -25.178 39.513  -32.315 0.27 18.88 ? 244  GLN H O   1 
ATOM   2636 O O   B GLN B 2  256 ? -25.267 39.492  -32.280 0.64 18.66 ? 244  GLN H O   1 
ATOM   2637 C CB  A GLN B 2  256 ? -27.852 37.918  -31.714 0.20 20.14 ? 244  GLN H CB  1 
ATOM   2638 C CB  B GLN B 2  256 ? -27.829 37.683  -31.788 0.71 20.13 ? 244  GLN H CB  1 
ATOM   2639 C CG  A GLN B 2  256 ? -29.269 38.177  -31.231 0.17 21.54 ? 244  GLN H CG  1 
ATOM   2640 C CG  B GLN B 2  256 ? -29.297 37.647  -31.408 0.63 22.06 ? 244  GLN H CG  1 
ATOM   2641 C CD  A GLN B 2  256 ? -29.463 39.596  -30.732 0.56 22.53 ? 244  GLN H CD  1 
ATOM   2642 C CD  B GLN B 2  256 ? -29.561 36.682  -30.266 0.44 23.27 ? 244  GLN H CD  1 
ATOM   2643 O OE1 A GLN B 2  256 ? -29.365 40.555  -31.497 0.10 22.98 ? 244  GLN H OE1 1 
ATOM   2644 O OE1 B GLN B 2  256 ? -29.054 36.860  -29.158 0.24 24.05 ? 244  GLN H OE1 1 
ATOM   2645 N NE2 A GLN B 2  256 ? -29.738 39.736  -29.442 0.10 22.81 ? 244  GLN H NE2 1 
ATOM   2646 N NE2 B GLN B 2  256 ? -30.350 35.650  -30.533 0.49 24.51 ? 244  GLN H NE2 1 
ATOM   2647 N N   . PHE B 2  257 ? -25.377 37.867  -33.825 1.00 18.72 ? 245  PHE H N   1 
ATOM   2648 C CA  . PHE B 2  257 ? -23.932 37.742  -33.954 1.00 17.99 ? 245  PHE H CA  1 
ATOM   2649 C C   . PHE B 2  257 ? -23.292 37.996  -35.310 1.00 16.91 ? 245  PHE H C   1 
ATOM   2650 O O   . PHE B 2  257 ? -22.067 37.971  -35.422 1.00 17.10 ? 245  PHE H O   1 
ATOM   2651 C CB  . PHE B 2  257 ? -23.535 36.341  -33.480 1.00 19.91 ? 245  PHE H CB  1 
ATOM   2652 C CG  . PHE B 2  257 ? -24.123 35.969  -32.146 1.00 20.51 ? 245  PHE H CG  1 
ATOM   2653 C CD1 . PHE B 2  257 ? -23.675 36.582  -30.983 1.00 22.07 ? 245  PHE H CD1 1 
ATOM   2654 C CD2 . PHE B 2  257 ? -25.140 35.021  -32.055 1.00 21.92 ? 245  PHE H CD2 1 
ATOM   2655 C CE1 . PHE B 2  257 ? -24.230 36.258  -29.745 1.00 23.78 ? 245  PHE H CE1 1 
ATOM   2656 C CE2 . PHE B 2  257 ? -25.701 34.691  -30.821 1.00 23.42 ? 245  PHE H CE2 1 
ATOM   2657 C CZ  . PHE B 2  257 ? -25.244 35.311  -29.665 1.00 23.33 ? 245  PHE H CZ  1 
ATOM   2658 N N   . GLY B 2  258 ? -24.109 38.250  -36.323 1.00 16.81 ? 246  GLY H N   1 
ATOM   2659 C CA  . GLY B 2  258 ? -23.595 38.447  -37.665 1.00 16.65 ? 246  GLY H CA  1 
ATOM   2660 C C   . GLY B 2  258 ? -22.739 39.663  -37.941 1.00 17.06 ? 246  GLY H C   1 
ATOM   2661 O O   . GLY B 2  258 ? -21.767 39.573  -38.687 1.00 16.47 ? 246  GLY H O   1 
ATOM   2662 N N   . GLU B 2  259 ? -23.083 40.803  -37.356 1.00 18.99 ? 247  GLU H N   1 
ATOM   2663 C CA  . GLU B 2  259 ? -22.306 42.005  -37.621 1.00 19.99 ? 247  GLU H CA  1 
ATOM   2664 C C   . GLU B 2  259 ? -20.909 41.949  -37.020 1.00 20.96 ? 247  GLU H C   1 
ATOM   2665 O O   . GLU B 2  259 ? -20.740 41.312  -35.961 1.00 21.32 ? 247  GLU H O   1 
ATOM   2666 C CB  . GLU B 2  259 ? -23.043 43.245  -37.105 1.00 20.53 ? 247  GLU H CB  1 
ATOM   2667 C CG  . GLU B 2  259 ? -22.473 44.534  -37.670 1.00 20.35 ? 247  GLU H CG  1 
ATOM   2668 C CD  . GLU B 2  259 ? -23.272 45.760  -37.285 1.00 20.90 ? 247  GLU H CD  1 
ATOM   2669 O OE1 . GLU B 2  259 ? -24.434 45.613  -36.851 1.00 20.47 ? 247  GLU H OE1 1 
ATOM   2670 O OE2 . GLU B 2  259 ? -22.734 46.878  -37.435 1.00 20.08 ? 247  GLU H OE2 1 
ATOM   2671 O OXT . GLU B 2  259 ? -19.995 42.562  -37.616 1.00 24.19 ? 247  GLU H OXT 1 
ATOM   2672 N N   . ASP C 3  36  ? 1.528   15.010  1.207   1.00 46.39 ? 28   ASP I N   1 
ATOM   2673 C CA  . ASP C 3  36  ? 1.096   14.506  2.542   1.00 45.50 ? 28   ASP I CA  1 
ATOM   2674 C C   . ASP C 3  36  ? 1.958   13.331  3.002   1.00 44.12 ? 28   ASP I C   1 
ATOM   2675 O O   . ASP C 3  36  ? 2.907   12.938  2.322   1.00 44.38 ? 28   ASP I O   1 
ATOM   2676 C CB  . ASP C 3  36  ? -0.373  14.076  2.489   1.00 45.98 ? 28   ASP I CB  1 
ATOM   2677 N N   . PHE C 3  37  ? 1.617   12.778  4.163   1.00 42.40 ? 29   PHE I N   1 
ATOM   2678 C CA  . PHE C 3  37  ? 2.345   11.648  4.736   1.00 41.08 ? 29   PHE I CA  1 
ATOM   2679 C C   . PHE C 3  37  ? 2.457   10.475  3.763   1.00 38.83 ? 29   PHE I C   1 
ATOM   2680 O O   . PHE C 3  37  ? 3.529   9.888   3.601   1.00 37.14 ? 29   PHE I O   1 
ATOM   2681 C CB  . PHE C 3  37  ? 1.658   11.205  6.035   1.00 42.44 ? 29   PHE I CB  1 
ATOM   2682 C CG  . PHE C 3  37  ? 2.030   9.820   6.485   1.00 44.25 ? 29   PHE I CG  1 
ATOM   2683 C CD1 . PHE C 3  37  ? 1.305   8.715   6.045   1.00 45.38 ? 29   PHE I CD1 1 
ATOM   2684 C CD2 . PHE C 3  37  ? 3.104   9.616   7.343   1.00 45.20 ? 29   PHE I CD2 1 
ATOM   2685 C CE1 . PHE C 3  37  ? 1.644   7.428   6.454   1.00 45.75 ? 29   PHE I CE1 1 
ATOM   2686 C CE2 . PHE C 3  37  ? 3.452   8.332   7.758   1.00 45.66 ? 29   PHE I CE2 1 
ATOM   2687 C CZ  . PHE C 3  37  ? 2.720   7.237   7.312   1.00 45.87 ? 29   PHE I CZ  1 
ATOM   2688 N N   . THR C 3  38  ? 1.345   10.137  3.122   1.00 36.82 ? 30   THR I N   1 
ATOM   2689 C CA  . THR C 3  38  ? 1.313   9.039   2.164   1.00 35.03 ? 30   THR I CA  1 
ATOM   2690 C C   . THR C 3  38  ? 2.370   9.204   1.078   1.00 33.90 ? 30   THR I C   1 
ATOM   2691 O O   . THR C 3  38  ? 3.052   8.248   0.707   1.00 32.58 ? 30   THR I O   1 
ATOM   2692 C CB  . THR C 3  38  ? -0.063  8.946   1.480   1.00 35.02 ? 30   THR I CB  1 
ATOM   2693 O OG1 . THR C 3  38  ? -1.039  8.502   2.429   1.00 34.13 ? 30   THR I OG1 1 
ATOM   2694 C CG2 . THR C 3  38  ? -0.016  7.976   0.301   1.00 34.87 ? 30   THR I CG2 1 
ATOM   2695 N N   . PHE C 3  39  ? 2.502   10.425  0.574   1.00 33.18 ? 31   PHE I N   1 
ATOM   2696 C CA  . PHE C 3  39  ? 3.453   10.710  -0.486  1.00 32.86 ? 31   PHE I CA  1 
ATOM   2697 C C   . PHE C 3  39  ? 4.885   10.861  0.006   1.00 32.49 ? 31   PHE I C   1 
ATOM   2698 O O   . PHE C 3  39  ? 5.827   10.552  -0.722  1.00 31.90 ? 31   PHE I O   1 
ATOM   2699 C CB  . PHE C 3  39  ? 2.974   11.939  -1.256  1.00 33.55 ? 31   PHE I CB  1 
ATOM   2700 C CG  . PHE C 3  39  ? 1.607   11.754  -1.849  1.00 34.13 ? 31   PHE I CG  1 
ATOM   2701 C CD1 . PHE C 3  39  ? 1.414   10.874  -2.912  1.00 33.86 ? 31   PHE I CD1 1 
ATOM   2702 C CD2 . PHE C 3  39  ? 0.500   12.379  -1.287  1.00 34.49 ? 31   PHE I CD2 1 
ATOM   2703 C CE1 . PHE C 3  39  ? 0.137   10.614  -3.402  1.00 34.62 ? 31   PHE I CE1 1 
ATOM   2704 C CE2 . PHE C 3  39  ? -0.783  12.126  -1.768  1.00 35.95 ? 31   PHE I CE2 1 
ATOM   2705 C CZ  . PHE C 3  39  ? -0.965  11.239  -2.828  1.00 35.04 ? 31   PHE I CZ  1 
ATOM   2706 N N   . ASP C 3  40  ? 5.051   11.325  1.241   1.00 33.32 ? 32   ASP I N   1 
ATOM   2707 C CA  . ASP C 3  40  ? 6.384   11.453  1.819   1.00 33.58 ? 32   ASP I CA  1 
ATOM   2708 C C   . ASP C 3  40  ? 6.927   10.036  1.989   1.00 33.21 ? 32   ASP I C   1 
ATOM   2709 O O   . ASP C 3  40  ? 8.116   9.780   1.786   1.00 33.15 ? 32   ASP I O   1 
ATOM   2710 C CB  . ASP C 3  40  ? 6.317   12.152  3.181   1.00 36.04 ? 32   ASP I CB  1 
ATOM   2711 C CG  . ASP C 3  40  ? 6.143   13.654  3.060   1.00 37.36 ? 32   ASP I CG  1 
ATOM   2712 O OD1 . ASP C 3  40  ? 5.891   14.310  4.093   1.00 38.70 ? 32   ASP I OD1 1 
ATOM   2713 O OD2 . ASP C 3  40  ? 6.270   14.181  1.936   1.00 38.40 ? 32   ASP I OD2 1 
ATOM   2714 N N   . LEU C 3  41  ? 6.042   9.114   2.358   1.00 31.33 ? 33   LEU I N   1 
ATOM   2715 C CA  . LEU C 3  41  ? 6.430   7.722   2.535   1.00 30.89 ? 33   LEU I CA  1 
ATOM   2716 C C   . LEU C 3  41  ? 6.776   7.128   1.177   1.00 29.90 ? 33   LEU I C   1 
ATOM   2717 O O   . LEU C 3  41  ? 7.793   6.449   1.027   1.00 28.68 ? 33   LEU I O   1 
ATOM   2718 C CB  . LEU C 3  41  ? 5.293   6.920   3.177   1.00 30.54 ? 33   LEU I CB  1 
ATOM   2719 C CG  . LEU C 3  41  ? 5.535   5.412   3.306   1.00 30.43 ? 33   LEU I CG  1 
ATOM   2720 C CD1 . LEU C 3  41  ? 6.809   5.149   4.104   1.00 31.67 ? 33   LEU I CD1 1 
ATOM   2721 C CD2 . LEU C 3  41  ? 4.337   4.761   3.977   1.00 30.27 ? 33   LEU I CD2 1 
ATOM   2722 N N   . TYR C 3  42  ? 5.932   7.386   0.182   1.00 29.32 ? 34   TYR I N   1 
ATOM   2723 C CA  . TYR C 3  42  ? 6.201   6.863   -1.150  1.00 28.11 ? 34   TYR I CA  1 
ATOM   2724 C C   . TYR C 3  42  ? 7.620   7.223   -1.572  1.00 27.87 ? 34   TYR I C   1 
ATOM   2725 O O   . TYR C 3  42  ? 8.413   6.352   -1.926  1.00 27.37 ? 34   TYR I O   1 
ATOM   2726 C CB  . TYR C 3  42  ? 5.235   7.434   -2.192  1.00 28.35 ? 34   TYR I CB  1 
ATOM   2727 C CG  . TYR C 3  42  ? 5.685   7.071   -3.587  1.00 26.03 ? 34   TYR I CG  1 
ATOM   2728 C CD1 . TYR C 3  42  ? 5.440   5.802   -4.109  1.00 26.71 ? 34   TYR I CD1 1 
ATOM   2729 C CD2 . TYR C 3  42  ? 6.487   7.943   -4.326  1.00 26.81 ? 34   TYR I CD2 1 
ATOM   2730 C CE1 . TYR C 3  42  ? 5.992   5.404   -5.323  1.00 27.74 ? 34   TYR I CE1 1 
ATOM   2731 C CE2 . TYR C 3  42  ? 7.044   7.553   -5.538  1.00 26.59 ? 34   TYR I CE2 1 
ATOM   2732 C CZ  . TYR C 3  42  ? 6.795   6.282   -6.028  1.00 27.62 ? 34   TYR I CZ  1 
ATOM   2733 O OH  . TYR C 3  42  ? 7.371   5.875   -7.208  1.00 28.66 ? 34   TYR I OH  1 
ATOM   2734 N N   . ARG C 3  43  ? 7.929   8.515   -1.544  1.00 29.62 ? 35   ARG I N   1 
ATOM   2735 C CA  . ARG C 3  43  ? 9.248   8.988   -1.941  1.00 31.81 ? 35   ARG I CA  1 
ATOM   2736 C C   . ARG C 3  43  ? 10.360  8.354   -1.111  1.00 32.87 ? 35   ARG I C   1 
ATOM   2737 O O   . ARG C 3  43  ? 11.421  8.015   -1.637  1.00 33.31 ? 35   ARG I O   1 
ATOM   2738 C CB  . ARG C 3  43  ? 9.307   10.517  -1.848  1.00 32.00 ? 35   ARG I CB  1 
ATOM   2739 C CG  . ARG C 3  43  ? 8.602   11.229  -3.008  1.00 34.16 ? 35   ARG I CG  1 
ATOM   2740 C CD  . ARG C 3  43  ? 8.734   12.744  -2.906  1.00 34.22 ? 35   ARG I CD  1 
ATOM   2741 N NE  . ARG C 3  43  ? 7.829   13.305  -1.908  1.00 33.58 ? 35   ARG I NE  1 
ATOM   2742 C CZ  . ARG C 3  43  ? 6.554   13.602  -2.136  1.00 34.27 ? 35   ARG I CZ  1 
ATOM   2743 N NH1 . ARG C 3  43  ? 6.023   13.400  -3.335  1.00 33.55 ? 35   ARG I NH1 1 
ATOM   2744 N NH2 . ARG C 3  43  ? 5.803   14.091  -1.158  1.00 34.63 ? 35   ARG I NH2 1 
ATOM   2745 N N   . ALA C 3  44  ? 10.111  8.184   0.183   1.00 33.91 ? 36   ALA I N   1 
ATOM   2746 C CA  . ALA C 3  44  ? 11.096  7.580   1.069   1.00 34.51 ? 36   ALA I CA  1 
ATOM   2747 C C   . ALA C 3  44  ? 11.397  6.150   0.627   1.00 34.29 ? 36   ALA I C   1 
ATOM   2748 O O   . ALA C 3  44  ? 12.547  5.720   0.639   1.00 35.03 ? 36   ALA I O   1 
ATOM   2749 C CB  . ALA C 3  44  ? 10.584  7.592   2.506   1.00 34.72 ? 36   ALA I CB  1 
ATOM   2750 N N   . LEU C 3  45  ? 10.359  5.418   0.233   1.00 34.24 ? 37   LEU I N   1 
ATOM   2751 C CA  . LEU C 3  45  ? 10.526  4.039   -0.210  1.00 34.47 ? 37   LEU I CA  1 
ATOM   2752 C C   . LEU C 3  45  ? 11.232  3.965   -1.559  1.00 36.39 ? 37   LEU I C   1 
ATOM   2753 O O   . LEU C 3  45  ? 12.090  3.109   -1.773  1.00 35.41 ? 37   LEU I O   1 
ATOM   2754 C CB  . LEU C 3  45  ? 9.166   3.342   -0.306  1.00 33.92 ? 37   LEU I CB  1 
ATOM   2755 C CG  . LEU C 3  45  ? 8.364   3.234   0.992   1.00 33.90 ? 37   LEU I CG  1 
ATOM   2756 C CD1 . LEU C 3  45  ? 7.047   2.524   0.721   1.00 34.21 ? 37   LEU I CD1 1 
ATOM   2757 C CD2 . LEU C 3  45  ? 9.176   2.474   2.034   1.00 34.68 ? 37   LEU I CD2 1 
ATOM   2758 N N   . ALA C 3  46  ? 10.865  4.862   -2.469  1.00 37.36 ? 38   ALA I N   1 
ATOM   2759 C CA  . ALA C 3  46  ? 11.476  4.891   -3.791  1.00 39.77 ? 38   ALA I CA  1 
ATOM   2760 C C   . ALA C 3  46  ? 12.951  5.267   -3.681  1.00 41.35 ? 38   ALA I C   1 
ATOM   2761 O O   . ALA C 3  46  ? 13.792  4.741   -4.409  1.00 41.97 ? 38   ALA I O   1 
ATOM   2762 C CB  . ALA C 3  46  ? 10.744  5.889   -4.685  1.00 39.67 ? 38   ALA I CB  1 
ATOM   2763 N N   . SER C 3  47  ? 13.257  6.181   -2.766  1.00 43.39 ? 39   SER I N   1 
ATOM   2764 C CA  . SER C 3  47  ? 14.630  6.624   -2.559  1.00 45.45 ? 39   SER I CA  1 
ATOM   2765 C C   . SER C 3  47  ? 15.490  5.484   -2.023  1.00 46.31 ? 39   SER I C   1 
ATOM   2766 O O   . SER C 3  47  ? 16.624  5.287   -2.462  1.00 46.45 ? 39   SER I O   1 
ATOM   2767 C CB  . SER C 3  47  ? 14.665  7.794   -1.574  1.00 46.17 ? 39   SER I CB  1 
ATOM   2768 O OG  . SER C 3  47  ? 13.941  8.906   -2.074  1.00 47.54 ? 39   SER I OG  1 
ATOM   2769 N N   . ALA C 3  48  ? 14.937  4.733   -1.077  1.00 46.64 ? 40   ALA I N   1 
ATOM   2770 C CA  . ALA C 3  48  ? 15.647  3.619   -0.465  1.00 46.54 ? 40   ALA I CA  1 
ATOM   2771 C C   . ALA C 3  48  ? 15.868  2.464   -1.434  1.00 46.92 ? 40   ALA I C   1 
ATOM   2772 O O   . ALA C 3  48  ? 16.814  1.691   -1.279  1.00 48.05 ? 40   ALA I O   1 
ATOM   2773 C CB  . ALA C 3  48  ? 14.883  3.132   0.762   1.00 46.18 ? 40   ALA I CB  1 
ATOM   2774 N N   . ALA C 3  49  ? 14.998  2.344   -2.433  1.00 46.86 ? 41   ALA I N   1 
ATOM   2775 C CA  . ALA C 3  49  ? 15.111  1.269   -3.416  1.00 46.21 ? 41   ALA I CA  1 
ATOM   2776 C C   . ALA C 3  49  ? 14.888  1.777   -4.840  1.00 46.39 ? 41   ALA I C   1 
ATOM   2777 O O   . ALA C 3  49  ? 13.876  1.466   -5.468  1.00 46.58 ? 41   ALA I O   1 
ATOM   2778 C CB  . ALA C 3  49  ? 14.114  0.163   -3.094  1.00 45.69 ? 41   ALA I CB  1 
ATOM   2779 N N   . PRO C 3  50  ? 15.840  2.563   -5.367  1.00 46.65 ? 42   PRO I N   1 
ATOM   2780 C CA  . PRO C 3  50  ? 15.766  3.127   -6.720  1.00 46.10 ? 42   PRO I CA  1 
ATOM   2781 C C   . PRO C 3  50  ? 15.635  2.073   -7.817  1.00 45.70 ? 42   PRO I C   1 
ATOM   2782 O O   . PRO C 3  50  ? 16.100  0.944   -7.667  1.00 45.54 ? 42   PRO I O   1 
ATOM   2783 C CB  . PRO C 3  50  ? 17.070  3.913   -6.834  1.00 46.84 ? 42   PRO I CB  1 
ATOM   2784 C CG  . PRO C 3  50  ? 17.328  4.341   -5.420  1.00 47.66 ? 42   PRO I CG  1 
ATOM   2785 C CD  . PRO C 3  50  ? 17.026  3.074   -4.657  1.00 46.86 ? 42   PRO I CD  1 
ATOM   2786 N N   . SER C 3  51  ? 14.998  2.456   -8.920  1.00 45.03 ? 43   SER I N   1 
ATOM   2787 C CA  . SER C 3  51  ? 14.803  1.566   -10.059 1.00 44.17 ? 43   SER I CA  1 
ATOM   2788 C C   . SER C 3  51  ? 14.163  0.242   -9.662  1.00 43.43 ? 43   SER I C   1 
ATOM   2789 O O   . SER C 3  51  ? 14.365  -0.779  -10.319 1.00 43.24 ? 43   SER I O   1 
ATOM   2790 C CB  . SER C 3  51  ? 16.141  1.300   -10.757 1.00 45.41 ? 43   SER I CB  1 
ATOM   2791 N N   . GLN C 3  52  ? 13.387  0.266   -8.584  1.00 42.61 ? 44   GLN I N   1 
ATOM   2792 C CA  . GLN C 3  52  ? 12.709  -0.931  -8.106  1.00 40.91 ? 44   GLN I CA  1 
ATOM   2793 C C   . GLN C 3  52  ? 11.215  -0.675  -7.984  1.00 37.94 ? 44   GLN I C   1 
ATOM   2794 O O   . GLN C 3  52  ? 10.785  0.465   -7.805  1.00 37.85 ? 44   GLN I O   1 
ATOM   2795 C CB  . GLN C 3  52  ? 13.260  -1.348  -6.739  1.00 43.24 ? 44   GLN I CB  1 
ATOM   2796 C CG  . GLN C 3  52  ? 14.691  -1.854  -6.765  1.00 46.34 ? 44   GLN I CG  1 
ATOM   2797 C CD  . GLN C 3  52  ? 14.834  -3.140  -7.549  1.00 48.42 ? 44   GLN I CD  1 
ATOM   2798 O OE1 . GLN C 3  52  ? 14.235  -4.161  -7.205  1.00 49.53 ? 44   GLN I OE1 1 
ATOM   2799 N NE2 . GLN C 3  52  ? 15.628  -3.100  -8.614  1.00 49.65 ? 44   GLN I NE2 1 
ATOM   2800 N N   . ASN C 3  53  ? 10.429  -1.739  -8.089  1.00 35.13 ? 45   ASN I N   1 
ATOM   2801 C CA  . ASN C 3  53  ? 8.985   -1.623  -7.955  1.00 33.15 ? 45   ASN I CA  1 
ATOM   2802 C C   . ASN C 3  53  ? 8.660   -1.157  -6.544  1.00 31.52 ? 45   ASN I C   1 
ATOM   2803 O O   . ASN C 3  53  ? 9.290   -1.591  -5.580  1.00 31.47 ? 45   ASN I O   1 
ATOM   2804 C CB  . ASN C 3  53  ? 8.311   -2.974  -8.201  1.00 32.37 ? 45   ASN I CB  1 
ATOM   2805 C CG  . ASN C 3  53  ? 8.144   -3.286  -9.670  1.00 33.56 ? 45   ASN I CG  1 
ATOM   2806 O OD1 . ASN C 3  53  ? 8.615   -2.546  -10.531 1.00 32.04 ? 45   ASN I OD1 1 
ATOM   2807 N ND2 . ASN C 3  53  ? 7.465   -4.389  -9.966  1.00 34.18 ? 45   ASN I ND2 1 
ATOM   2808 N N   . ILE C 3  54  ? 7.686   -0.263  -6.431  1.00 29.80 ? 46   ILE I N   1 
ATOM   2809 C CA  . ILE C 3  54  ? 7.248   0.242   -5.137  1.00 27.06 ? 46   ILE I CA  1 
ATOM   2810 C C   . ILE C 3  54  ? 5.743   0.022   -5.114  1.00 26.90 ? 46   ILE I C   1 
ATOM   2811 O O   . ILE C 3  54  ? 5.054   0.353   -6.077  1.00 24.92 ? 46   ILE I O   1 
ATOM   2812 C CB  . ILE C 3  54  ? 7.542   1.748   -4.972  1.00 28.15 ? 46   ILE I CB  1 
ATOM   2813 C CG1 . ILE C 3  54  ? 9.045   2.010   -5.088  1.00 27.53 ? 46   ILE I CG1 1 
ATOM   2814 C CG2 . ILE C 3  54  ? 7.029   2.231   -3.618  1.00 28.21 ? 46   ILE I CG2 1 
ATOM   2815 C CD1 . ILE C 3  54  ? 9.884   1.308   -4.031  1.00 29.11 ? 46   ILE I CD1 1 
ATOM   2816 N N   . PHE C 3  55  ? 5.227   -0.554  -4.035  1.00 25.52 ? 47   PHE I N   1 
ATOM   2817 C CA  . PHE C 3  55  ? 3.795   -0.800  -3.965  1.00 24.19 ? 47   PHE I CA  1 
ATOM   2818 C C   . PHE C 3  55  ? 3.307   -1.021  -2.541  1.00 25.08 ? 47   PHE I C   1 
ATOM   2819 O O   . PHE C 3  55  ? 3.748   -1.950  -1.860  1.00 24.53 ? 47   PHE I O   1 
ATOM   2820 C CB  . PHE C 3  55  ? 3.432   -2.020  -4.810  1.00 25.05 ? 47   PHE I CB  1 
ATOM   2821 C CG  . PHE C 3  55  ? 1.962   -2.150  -5.079  1.00 25.89 ? 47   PHE I CG  1 
ATOM   2822 C CD1 . PHE C 3  55  ? 1.325   -1.271  -5.951  1.00 26.58 ? 47   PHE I CD1 1 
ATOM   2823 C CD2 . PHE C 3  55  ? 1.206   -3.127  -4.442  1.00 25.58 ? 47   PHE I CD2 1 
ATOM   2824 C CE1 . PHE C 3  55  ? -0.044  -1.363  -6.180  1.00 26.07 ? 47   PHE I CE1 1 
ATOM   2825 C CE2 . PHE C 3  55  ? -0.168  -3.226  -4.667  1.00 26.00 ? 47   PHE I CE2 1 
ATOM   2826 C CZ  . PHE C 3  55  ? -0.791  -2.341  -5.538  1.00 26.50 ? 47   PHE I CZ  1 
ATOM   2827 N N   . PHE C 3  56  ? 2.392   -0.166  -2.095  1.00 23.30 ? 48   PHE I N   1 
ATOM   2828 C CA  . PHE C 3  56  ? 1.840   -0.298  -0.756  1.00 24.46 ? 48   PHE I CA  1 
ATOM   2829 C C   . PHE C 3  56  ? 0.431   0.277   -0.669  1.00 24.82 ? 48   PHE I C   1 
ATOM   2830 O O   . PHE C 3  56  ? -0.058  0.911   -1.609  1.00 24.22 ? 48   PHE I O   1 
ATOM   2831 C CB  . PHE C 3  56  ? 2.743   0.392   0.272   1.00 24.75 ? 48   PHE I CB  1 
ATOM   2832 C CG  . PHE C 3  56  ? 2.799   1.889   0.136   1.00 24.66 ? 48   PHE I CG  1 
ATOM   2833 C CD1 . PHE C 3  56  ? 3.570   2.488   -0.857  1.00 25.77 ? 48   PHE I CD1 1 
ATOM   2834 C CD2 . PHE C 3  56  ? 2.094   2.702   1.017   1.00 23.90 ? 48   PHE I CD2 1 
ATOM   2835 C CE1 . PHE C 3  56  ? 3.639   3.877   -0.967  1.00 25.57 ? 48   PHE I CE1 1 
ATOM   2836 C CE2 . PHE C 3  56  ? 2.155   4.091   0.917   1.00 24.19 ? 48   PHE I CE2 1 
ATOM   2837 C CZ  . PHE C 3  56  ? 2.929   4.681   -0.076  1.00 25.59 ? 48   PHE I CZ  1 
ATOM   2838 N N   . SER C 3  57  ? -0.218  0.039   0.465   1.00 23.90 ? 49   SER I N   1 
ATOM   2839 C CA  . SER C 3  57  ? -1.568  0.535   0.701   1.00 22.86 ? 49   SER I CA  1 
ATOM   2840 C C   . SER C 3  57  ? -1.510  1.641   1.748   1.00 23.41 ? 49   SER I C   1 
ATOM   2841 O O   . SER C 3  57  ? -1.287  1.376   2.931   1.00 24.04 ? 49   SER I O   1 
ATOM   2842 C CB  . SER C 3  57  ? -2.470  -0.598  1.191   1.00 23.77 ? 49   SER I CB  1 
ATOM   2843 O OG  . SER C 3  57  ? -3.744  -0.104  1.567   1.00 23.35 ? 49   SER I OG  1 
ATOM   2844 N N   . PRO C 3  58  ? -1.698  2.898   1.323   1.00 23.38 ? 50   PRO I N   1 
ATOM   2845 C CA  . PRO C 3  58  ? -1.665  4.048   2.230   1.00 26.12 ? 50   PRO I CA  1 
ATOM   2846 C C   . PRO C 3  58  ? -2.686  3.964   3.362   1.00 27.94 ? 50   PRO I C   1 
ATOM   2847 O O   . PRO C 3  58  ? -2.359  4.222   4.522   1.00 29.14 ? 50   PRO I O   1 
ATOM   2848 C CB  . PRO C 3  58  ? -1.932  5.225   1.298   1.00 26.34 ? 50   PRO I CB  1 
ATOM   2849 C CG  . PRO C 3  58  ? -1.292  4.776   0.020   1.00 25.43 ? 50   PRO I CG  1 
ATOM   2850 C CD  . PRO C 3  58  ? -1.777  3.346   -0.079  1.00 23.89 ? 50   PRO I CD  1 
ATOM   2851 N N   . VAL C 3  59  ? -3.919  3.593   3.030   1.00 27.78 ? 51   VAL I N   1 
ATOM   2852 C CA  . VAL C 3  59  ? -4.960  3.498   4.045   1.00 28.13 ? 51   VAL I CA  1 
ATOM   2853 C C   . VAL C 3  59  ? -4.687  2.348   5.013   1.00 28.46 ? 51   VAL I C   1 
ATOM   2854 O O   . VAL C 3  59  ? -4.990  2.441   6.204   1.00 28.00 ? 51   VAL I O   1 
ATOM   2855 C CB  . VAL C 3  59  ? -6.361  3.325   3.404   1.00 28.92 ? 51   VAL I CB  1 
ATOM   2856 C CG1 . VAL C 3  59  ? -6.483  1.962   2.749   1.00 28.05 ? 51   VAL I CG1 1 
ATOM   2857 C CG2 . VAL C 3  59  ? -7.439  3.524   4.462   1.00 29.77 ? 51   VAL I CG2 1 
ATOM   2858 N N   . SER C 3  60  ? -4.103  1.269   4.504   1.00 27.76 ? 52   SER I N   1 
ATOM   2859 C CA  . SER C 3  60  ? -3.789  0.118   5.340   1.00 29.23 ? 52   SER I CA  1 
ATOM   2860 C C   . SER C 3  60  ? -2.698  0.468   6.355   1.00 29.29 ? 52   SER I C   1 
ATOM   2861 O O   . SER C 3  60  ? -2.742  0.024   7.504   1.00 29.47 ? 52   SER I O   1 
ATOM   2862 C CB  . SER C 3  60  ? -3.338  -1.057  4.475   1.00 29.32 ? 52   SER I CB  1 
ATOM   2863 O OG  . SER C 3  60  ? -3.116  -2.206  5.268   1.00 35.85 ? 52   SER I OG  1 
ATOM   2864 N N   . ILE C 3  61  ? -1.716  1.259   5.932   1.00 28.69 ? 53   ILE I N   1 
ATOM   2865 C CA  . ILE C 3  61  ? -0.645  1.653   6.837   1.00 27.65 ? 53   ILE I CA  1 
ATOM   2866 C C   . ILE C 3  61  ? -1.182  2.656   7.852   1.00 28.89 ? 53   ILE I C   1 
ATOM   2867 O O   . ILE C 3  61  ? -0.782  2.643   9.017   1.00 28.62 ? 53   ILE I O   1 
ATOM   2868 C CB  . ILE C 3  61  ? 0.548   2.271   6.075   1.00 28.47 ? 53   ILE I CB  1 
ATOM   2869 C CG1 . ILE C 3  61  ? 1.203   1.201   5.195   1.00 27.55 ? 53   ILE I CG1 1 
ATOM   2870 C CG2 . ILE C 3  61  ? 1.566   2.832   7.061   1.00 28.32 ? 53   ILE I CG2 1 
ATOM   2871 C CD1 . ILE C 3  61  ? 2.437   1.680   4.442   1.00 25.53 ? 53   ILE I CD1 1 
ATOM   2872 N N   . SER C 3  62  ? -2.091  3.521   7.412   1.00 28.42 ? 54   SER I N   1 
ATOM   2873 C CA  . SER C 3  62  ? -2.685  4.504   8.311   1.00 30.01 ? 54   SER I CA  1 
ATOM   2874 C C   . SER C 3  62  ? -3.456  3.764   9.398   1.00 29.25 ? 54   SER I C   1 
ATOM   2875 O O   . SER C 3  62  ? -3.420  4.146   10.567  1.00 30.21 ? 54   SER I O   1 
ATOM   2876 C CB  . SER C 3  62  ? -3.628  5.435   7.547   1.00 29.80 ? 54   SER I CB  1 
ATOM   2877 O OG  . SER C 3  62  ? -2.899  6.309   6.705   1.00 34.09 ? 54   SER I OG  1 
ATOM   2878 N N   A MET C 3  63  ? -4.151  2.705   8.995   0.25 29.19 ? 55   MET I N   1 
ATOM   2879 N N   B MET C 3  63  ? -4.151  2.697   9.015   0.75 29.77 ? 55   MET I N   1 
ATOM   2880 C CA  A MET C 3  63  ? -4.938  1.897   9.916   0.37 28.74 ? 55   MET I CA  1 
ATOM   2881 C CA  B MET C 3  63  ? -4.904  1.911   9.986   0.63 29.62 ? 55   MET I CA  1 
ATOM   2882 C C   A MET C 3  63  ? -4.029  1.233   10.945  0.14 28.21 ? 55   MET I C   1 
ATOM   2883 C C   B MET C 3  63  ? -3.943  1.295   10.996  0.42 28.67 ? 55   MET I C   1 
ATOM   2884 O O   A MET C 3  63  ? -4.369  1.153   12.126  0.21 28.06 ? 55   MET I O   1 
ATOM   2885 O O   B MET C 3  63  ? -4.180  1.343   12.204  0.79 28.66 ? 55   MET I O   1 
ATOM   2886 C CB  A MET C 3  63  ? -5.713  0.830   9.140   0.28 29.06 ? 55   MET I CB  1 
ATOM   2887 C CB  B MET C 3  63  ? -5.688  0.794   9.293   0.72 30.84 ? 55   MET I CB  1 
ATOM   2888 C CG  A MET C 3  63  ? -6.678  0.018   9.983   0.56 29.43 ? 55   MET I CG  1 
ATOM   2889 C CG  B MET C 3  63  ? -6.841  1.273   8.432   0.44 31.93 ? 55   MET I CG  1 
ATOM   2890 S SD  A MET C 3  63  ? -7.599  -1.180  9.001   0.40 29.18 ? 55   MET I SD  1 
ATOM   2891 S SD  B MET C 3  63  ? -7.873  -0.090  7.858   0.38 32.74 ? 55   MET I SD  1 
ATOM   2892 C CE  A MET C 3  63  ? -8.878  -0.138  8.308   0.33 29.46 ? 55   MET I CE  1 
ATOM   2893 C CE  B MET C 3  63  ? -8.866  -0.392  9.315   0.36 32.92 ? 55   MET I CE  1 
ATOM   2894 N N   A SER C 3  64  ? -2.874  0.757   10.490  0.28 27.66 ? 56   SER I N   1 
ATOM   2895 N N   B SER C 3  64  ? -2.856  0.718   10.489  0.72 27.56 ? 56   SER I N   1 
ATOM   2896 C CA  A SER C 3  64  ? -1.915  0.105   11.374  0.27 27.33 ? 56   SER I CA  1 
ATOM   2897 C CA  B SER C 3  64  ? -1.848  0.085   11.333  0.66 27.03 ? 56   SER I CA  1 
ATOM   2898 C C   A SER C 3  64  ? -1.377  1.095   12.396  0.21 27.08 ? 56   SER I C   1 
ATOM   2899 C C   B SER C 3  64  ? -1.303  1.066   12.367  0.79 26.91 ? 56   SER I C   1 
ATOM   2900 O O   A SER C 3  64  ? -1.273  0.782   13.582  0.22 26.89 ? 56   SER I O   1 
ATOM   2901 O O   B SER C 3  64  ? -1.135  0.720   13.536  0.75 26.42 ? 56   SER I O   1 
ATOM   2902 C CB  A SER C 3  64  ? -0.753  -0.474  10.565  0.20 27.63 ? 56   SER I CB  1 
ATOM   2903 C CB  B SER C 3  64  ? -0.699  -0.448  10.470  0.80 27.16 ? 56   SER I CB  1 
ATOM   2904 O OG  A SER C 3  64  ? -1.198  -1.510  9.711   0.41 28.07 ? 56   SER I OG  1 
ATOM   2905 O OG  B SER C 3  64  ? 0.272   -1.105  11.265  0.37 26.60 ? 56   SER I OG  1 
ATOM   2906 N N   . LEU C 3  65  ? -1.033  2.292   11.931  1.00 26.47 ? 57   LEU I N   1 
ATOM   2907 C CA  . LEU C 3  65  ? -0.511  3.320   12.819  1.00 26.91 ? 57   LEU I CA  1 
ATOM   2908 C C   . LEU C 3  65  ? -1.564  3.732   13.844  1.00 27.93 ? 57   LEU I C   1 
ATOM   2909 O O   . LEU C 3  65  ? -1.261  3.869   15.030  1.00 27.19 ? 57   LEU I O   1 
ATOM   2910 C CB  . LEU C 3  65  ? -0.055  4.537   12.010  1.00 28.05 ? 57   LEU I CB  1 
ATOM   2911 C CG  . LEU C 3  65  ? 1.220   4.327   11.185  1.00 28.17 ? 57   LEU I CG  1 
ATOM   2912 C CD1 . LEU C 3  65  ? 1.504   5.561   10.347  1.00 29.65 ? 57   LEU I CD1 1 
ATOM   2913 C CD2 . LEU C 3  65  ? 2.386   4.032   12.120  1.00 27.92 ? 57   LEU I CD2 1 
ATOM   2914 N N   . ALA C 3  66  ? -2.799  3.922   13.389  1.00 27.46 ? 58   ALA I N   1 
ATOM   2915 C CA  . ALA C 3  66  ? -3.887  4.310   14.285  1.00 29.12 ? 58   ALA I CA  1 
ATOM   2916 C C   . ALA C 3  66  ? -4.034  3.253   15.373  1.00 28.82 ? 58   ALA I C   1 
ATOM   2917 O O   . ALA C 3  66  ? -4.169  3.566   16.556  1.00 29.07 ? 58   ALA I O   1 
ATOM   2918 C CB  . ALA C 3  66  ? -5.191  4.443   13.503  1.00 29.86 ? 58   ALA I CB  1 
ATOM   2919 N N   . MET C 3  67  ? -3.997  1.995   14.954  1.00 29.03 ? 59   MET I N   1 
ATOM   2920 C CA  . MET C 3  67  ? -4.118  0.864   15.861  1.00 30.69 ? 59   MET I CA  1 
ATOM   2921 C C   . MET C 3  67  ? -2.990  0.904   16.890  1.00 30.16 ? 59   MET I C   1 
ATOM   2922 O O   . MET C 3  67  ? -3.214  0.741   18.089  1.00 29.94 ? 59   MET I O   1 
ATOM   2923 C CB  . MET C 3  67  ? -4.034  -0.429  15.058  1.00 32.36 ? 59   MET I CB  1 
ATOM   2924 C CG  . MET C 3  67  ? -4.537  -1.654  15.771  1.00 35.69 ? 59   MET I CG  1 
ATOM   2925 S SD  . MET C 3  67  ? -4.146  -3.144  14.844  1.00 40.40 ? 59   MET I SD  1 
ATOM   2926 C CE  . MET C 3  67  ? -4.624  -2.634  13.207  1.00 39.20 ? 59   MET I CE  1 
ATOM   2927 N N   . LEU C 3  68  ? -1.774  1.129   16.412  1.00 29.71 ? 60   LEU I N   1 
ATOM   2928 C CA  . LEU C 3  68  ? -0.615  1.183   17.291  1.00 29.53 ? 60   LEU I CA  1 
ATOM   2929 C C   . LEU C 3  68  ? -0.761  2.302   18.319  1.00 28.77 ? 60   LEU I C   1 
ATOM   2930 O O   . LEU C 3  68  ? -0.394  2.135   19.483  1.00 29.12 ? 60   LEU I O   1 
ATOM   2931 C CB  . LEU C 3  68  ? 0.655   1.407   16.467  1.00 30.74 ? 60   LEU I CB  1 
ATOM   2932 C CG  . LEU C 3  68  ? 2.006   0.971   17.045  1.00 33.49 ? 60   LEU I CG  1 
ATOM   2933 C CD1 . LEU C 3  68  ? 3.103   1.389   16.081  1.00 31.72 ? 60   LEU I CD1 1 
ATOM   2934 C CD2 . LEU C 3  68  ? 2.243   1.590   18.414  1.00 35.92 ? 60   LEU I CD2 1 
ATOM   2935 N N   . SER C 3  69  ? -1.299  3.441   17.896  1.00 27.02 ? 61   SER I N   1 
ATOM   2936 C CA  . SER C 3  69  ? -1.456  4.574   18.803  1.00 27.05 ? 61   SER I CA  1 
ATOM   2937 C C   . SER C 3  69  ? -2.337  4.244   20.004  1.00 27.11 ? 61   SER I C   1 
ATOM   2938 O O   . SER C 3  69  ? -2.343  4.979   20.988  1.00 27.79 ? 61   SER I O   1 
ATOM   2939 C CB  . SER C 3  69  ? -2.041  5.783   18.067  1.00 27.44 ? 61   SER I CB  1 
ATOM   2940 O OG  . SER C 3  69  ? -3.425  5.612   17.833  1.00 28.09 ? 61   SER I OG  1 
ATOM   2941 N N   . LEU C 3  70  ? -3.081  3.146   19.921  1.00 26.52 ? 62   LEU I N   1 
ATOM   2942 C CA  . LEU C 3  70  ? -3.958  2.742   21.017  1.00 27.18 ? 62   LEU I CA  1 
ATOM   2943 C C   . LEU C 3  70  ? -3.152  2.351   22.251  1.00 29.21 ? 62   LEU I C   1 
ATOM   2944 O O   . LEU C 3  70  ? -3.620  2.502   23.379  1.00 29.06 ? 62   LEU I O   1 
ATOM   2945 C CB  . LEU C 3  70  ? -4.830  1.556   20.599  1.00 27.09 ? 62   LEU I CB  1 
ATOM   2946 C CG  . LEU C 3  70  ? -5.915  1.790   19.543  1.00 29.53 ? 62   LEU I CG  1 
ATOM   2947 C CD1 . LEU C 3  70  ? -6.516  0.456   19.126  1.00 28.91 ? 62   LEU I CD1 1 
ATOM   2948 C CD2 . LEU C 3  70  ? -6.989  2.709   20.106  1.00 30.27 ? 62   LEU I CD2 1 
ATOM   2949 N N   . GLY C 3  71  ? -1.944  1.842   22.033  1.00 29.08 ? 63   GLY I N   1 
ATOM   2950 C CA  . GLY C 3  71  ? -1.118  1.431   23.153  1.00 30.99 ? 63   GLY I CA  1 
ATOM   2951 C C   . GLY C 3  71  ? 0.069   2.336   23.409  1.00 31.81 ? 63   GLY I C   1 
ATOM   2952 O O   . GLY C 3  71  ? 0.928   2.015   24.231  1.00 32.11 ? 63   GLY I O   1 
ATOM   2953 N N   . ALA C 3  72  ? 0.119   3.469   22.718  1.00 31.59 ? 64   ALA I N   1 
ATOM   2954 C CA  . ALA C 3  72  ? 1.225   4.402   22.878  1.00 33.19 ? 64   ALA I CA  1 
ATOM   2955 C C   . ALA C 3  72  ? 0.877   5.560   23.806  1.00 34.28 ? 64   ALA I C   1 
ATOM   2956 O O   . ALA C 3  72  ? -0.294  5.816   24.088  1.00 35.55 ? 64   ALA I O   1 
ATOM   2957 C CB  . ALA C 3  72  ? 1.654   4.935   21.516  1.00 31.26 ? 64   ALA I CB  1 
ATOM   2958 N N   . GLY C 3  73  ? 1.908   6.254   24.277  1.00 34.93 ? 65   GLY I N   1 
ATOM   2959 C CA  . GLY C 3  73  ? 1.705   7.386   25.162  1.00 35.68 ? 65   GLY I CA  1 
ATOM   2960 C C   . GLY C 3  73  ? 2.776   8.443   24.969  1.00 36.76 ? 65   GLY I C   1 
ATOM   2961 O O   . GLY C 3  73  ? 3.687   8.270   24.159  1.00 35.31 ? 65   GLY I O   1 
ATOM   2962 N N   . SER C 3  74  ? 2.663   9.542   25.709  1.00 37.88 ? 66   SER I N   1 
ATOM   2963 C CA  . SER C 3  74  ? 3.632   10.633  25.632  1.00 39.90 ? 66   SER I CA  1 
ATOM   2964 C C   . SER C 3  74  ? 3.942   11.051  24.197  1.00 39.67 ? 66   SER I C   1 
ATOM   2965 O O   . SER C 3  74  ? 3.054   11.098  23.345  1.00 40.67 ? 66   SER I O   1 
ATOM   2966 C CB  . SER C 3  74  ? 4.933   10.232  26.333  1.00 40.20 ? 66   SER I CB  1 
ATOM   2967 O OG  . SER C 3  74  ? 4.704   9.918   27.694  1.00 44.53 ? 66   SER I OG  1 
ATOM   2968 N N   . SER C 3  75  ? 5.213   11.354  23.944  1.00 39.29 ? 67   SER I N   1 
ATOM   2969 C CA  . SER C 3  75  ? 5.665   11.777  22.623  1.00 39.15 ? 67   SER I CA  1 
ATOM   2970 C C   . SER C 3  75  ? 5.580   10.645  21.604  1.00 38.92 ? 67   SER I C   1 
ATOM   2971 O O   . SER C 3  75  ? 5.405   10.891  20.409  1.00 38.88 ? 67   SER I O   1 
ATOM   2972 C CB  . SER C 3  75  ? 7.105   12.296  22.699  1.00 39.61 ? 67   SER I CB  1 
ATOM   2973 O OG  . SER C 3  75  ? 7.979   11.311  23.222  1.00 40.41 ? 67   SER I OG  1 
ATOM   2974 N N   . THR C 3  76  ? 5.710   9.408   22.075  1.00 37.24 ? 68   THR I N   1 
ATOM   2975 C CA  . THR C 3  76  ? 5.632   8.252   21.192  1.00 36.59 ? 68   THR I CA  1 
ATOM   2976 C C   . THR C 3  76  ? 4.297   8.279   20.458  1.00 37.08 ? 68   THR I C   1 
ATOM   2977 O O   . THR C 3  76  ? 4.232   8.053   19.249  1.00 35.74 ? 68   THR I O   1 
ATOM   2978 C CB  . THR C 3  76  ? 5.742   6.931   21.983  1.00 35.50 ? 68   THR I CB  1 
ATOM   2979 O OG1 . THR C 3  76  ? 7.055   6.817   22.542  1.00 33.26 ? 68   THR I OG1 1 
ATOM   2980 C CG2 . THR C 3  76  ? 5.479   5.736   21.074  1.00 35.92 ? 68   THR I CG2 1 
ATOM   2981 N N   . LYS C 3  77  ? 3.236   8.569   21.202  1.00 38.10 ? 69   LYS I N   1 
ATOM   2982 C CA  . LYS C 3  77  ? 1.895   8.634   20.636  1.00 39.72 ? 69   LYS I CA  1 
ATOM   2983 C C   . LYS C 3  77  ? 1.741   9.856   19.733  1.00 40.98 ? 69   LYS I C   1 
ATOM   2984 O O   . LYS C 3  77  ? 1.174   9.766   18.643  1.00 41.00 ? 69   LYS I O   1 
ATOM   2985 C CB  . LYS C 3  77  ? 0.861   8.688   21.762  1.00 40.16 ? 69   LYS I CB  1 
ATOM   2986 C CG  . LYS C 3  77  ? -0.583  8.704   21.292  1.00 40.89 ? 69   LYS I CG  1 
ATOM   2987 C CD  . LYS C 3  77  ? -1.532  8.697   22.478  1.00 41.37 ? 69   LYS I CD  1 
ATOM   2988 C CE  . LYS C 3  77  ? -2.979  8.638   22.028  1.00 43.13 ? 69   LYS I CE  1 
ATOM   2989 N NZ  . LYS C 3  77  ? -3.911  8.593   23.189  1.00 43.91 ? 69   LYS I NZ  1 
ATOM   2990 N N   . MET C 3  78  ? 2.254   10.993  20.191  1.00 41.17 ? 70   MET I N   1 
ATOM   2991 C CA  . MET C 3  78  ? 2.169   12.237  19.434  1.00 42.31 ? 70   MET I CA  1 
ATOM   2992 C C   . MET C 3  78  ? 2.761   12.115  18.031  1.00 41.75 ? 70   MET I C   1 
ATOM   2993 O O   . MET C 3  78  ? 2.165   12.583  17.059  1.00 41.45 ? 70   MET I O   1 
ATOM   2994 C CB  . MET C 3  78  ? 2.876   13.363  20.192  1.00 44.34 ? 70   MET I CB  1 
ATOM   2995 C CG  . MET C 3  78  ? 2.388   13.542  21.618  1.00 47.56 ? 70   MET I CG  1 
ATOM   2996 S SD  . MET C 3  78  ? 3.144   14.953  22.453  1.00 51.94 ? 70   MET I SD  1 
ATOM   2997 C CE  . MET C 3  78  ? 1.730   15.602  23.355  1.00 49.85 ? 70   MET I CE  1 
ATOM   2998 N N   . GLN C 3  79  ? 3.930   11.490  17.926  1.00 40.21 ? 71   GLN I N   1 
ATOM   2999 C CA  . GLN C 3  79  ? 4.583   11.323  16.631  1.00 39.89 ? 71   GLN I CA  1 
ATOM   3000 C C   . GLN C 3  79  ? 3.694   10.541  15.675  1.00 39.76 ? 71   GLN I C   1 
ATOM   3001 O O   . GLN C 3  79  ? 3.614   10.860  14.488  1.00 38.78 ? 71   GLN I O   1 
ATOM   3002 C CB  . GLN C 3  79  ? 5.918   10.590  16.785  1.00 40.10 ? 71   GLN I CB  1 
ATOM   3003 C CG  . GLN C 3  79  ? 6.878   11.229  17.769  1.00 39.75 ? 71   GLN I CG  1 
ATOM   3004 C CD  . GLN C 3  79  ? 8.242   10.571  17.750  1.00 39.91 ? 71   GLN I CD  1 
ATOM   3005 O OE1 . GLN C 3  79  ? 8.354   9.344   17.713  1.00 39.03 ? 71   GLN I OE1 1 
ATOM   3006 N NE2 . GLN C 3  79  ? 9.291   11.383  17.786  1.00 39.08 ? 71   GLN I NE2 1 
ATOM   3007 N N   . ILE C 3  80  ? 3.030   9.515   16.198  1.00 39.11 ? 72   ILE I N   1 
ATOM   3008 C CA  . ILE C 3  80  ? 2.148   8.682   15.390  1.00 39.21 ? 72   ILE I CA  1 
ATOM   3009 C C   . ILE C 3  80  ? 0.949   9.482   14.891  1.00 41.21 ? 72   ILE I C   1 
ATOM   3010 O O   . ILE C 3  80  ? 0.608   9.430   13.707  1.00 41.11 ? 72   ILE I O   1 
ATOM   3011 C CB  . ILE C 3  80  ? 1.641   7.463   16.193  1.00 37.67 ? 72   ILE I CB  1 
ATOM   3012 C CG1 . ILE C 3  80  ? 2.827   6.594   16.622  1.00 36.27 ? 72   ILE I CG1 1 
ATOM   3013 C CG2 . ILE C 3  80  ? 0.674   6.646   15.349  1.00 36.66 ? 72   ILE I CG2 1 
ATOM   3014 C CD1 . ILE C 3  80  ? 2.443   5.401   17.482  1.00 34.25 ? 72   ILE I CD1 1 
ATOM   3015 N N   . LEU C 3  81  ? 0.314   10.222  15.794  1.00 42.82 ? 73   LEU I N   1 
ATOM   3016 C CA  . LEU C 3  81  ? -0.845  11.028  15.433  1.00 44.75 ? 73   LEU I CA  1 
ATOM   3017 C C   . LEU C 3  81  ? -0.459  12.099  14.416  1.00 46.38 ? 73   LEU I C   1 
ATOM   3018 O O   . LEU C 3  81  ? -1.156  12.294  13.419  1.00 46.65 ? 73   LEU I O   1 
ATOM   3019 C CB  . LEU C 3  81  ? -1.449  11.677  16.681  1.00 44.87 ? 73   LEU I CB  1 
ATOM   3020 C CG  . LEU C 3  81  ? -1.933  10.712  17.768  1.00 44.93 ? 73   LEU I CG  1 
ATOM   3021 C CD1 . LEU C 3  81  ? -2.556  11.502  18.910  1.00 45.17 ? 73   LEU I CD1 1 
ATOM   3022 C CD2 . LEU C 3  81  ? -2.945  9.735   17.185  1.00 43.89 ? 73   LEU I CD2 1 
ATOM   3023 N N   . GLU C 3  82  ? 0.651   12.787  14.667  1.00 47.89 ? 74   GLU I N   1 
ATOM   3024 C CA  . GLU C 3  82  ? 1.121   13.822  13.752  1.00 49.99 ? 74   GLU I CA  1 
ATOM   3025 C C   . GLU C 3  82  ? 1.358   13.213  12.375  1.00 50.34 ? 74   GLU I C   1 
ATOM   3026 O O   . GLU C 3  82  ? 1.086   13.841  11.353  1.00 50.58 ? 74   GLU I O   1 
ATOM   3027 C CB  . GLU C 3  82  ? 2.421   14.450  14.263  1.00 51.34 ? 74   GLU I CB  1 
ATOM   3028 C CG  . GLU C 3  82  ? 2.259   15.305  15.510  1.00 54.41 ? 74   GLU I CG  1 
ATOM   3029 C CD  . GLU C 3  82  ? 3.568   15.928  15.961  1.00 55.90 ? 74   GLU I CD  1 
ATOM   3030 O OE1 . GLU C 3  82  ? 4.192   16.653  15.156  1.00 57.61 ? 74   GLU I OE1 1 
ATOM   3031 O OE2 . GLU C 3  82  ? 3.974   15.694  17.119  1.00 56.67 ? 74   GLU I OE2 1 
ATOM   3032 N N   . GLY C 3  83  ? 1.869   11.986  12.359  1.00 50.85 ? 75   GLY I N   1 
ATOM   3033 C CA  . GLY C 3  83  ? 2.128   11.307  11.104  1.00 51.72 ? 75   GLY I CA  1 
ATOM   3034 C C   . GLY C 3  83  ? 0.845   11.065  10.336  1.00 52.65 ? 75   GLY I C   1 
ATOM   3035 O O   . GLY C 3  83  ? 0.809   11.193  9.112   1.00 53.01 ? 75   GLY I O   1 
ATOM   3036 N N   . LEU C 3  84  ? -0.213  10.707  11.057  1.00 53.00 ? 76   LEU I N   1 
ATOM   3037 C CA  . LEU C 3  84  ? -1.509  10.459  10.439  1.00 54.10 ? 76   LEU I CA  1 
ATOM   3038 C C   . LEU C 3  84  ? -2.216  11.786  10.192  1.00 54.88 ? 76   LEU I C   1 
ATOM   3039 O O   . LEU C 3  84  ? -3.341  11.819  9.693   1.00 54.82 ? 76   LEU I O   1 
ATOM   3040 C CB  . LEU C 3  84  ? -2.377  9.583   11.348  1.00 53.26 ? 76   LEU I CB  1 
ATOM   3041 C CG  . LEU C 3  84  ? -1.890  8.161   11.629  1.00 53.03 ? 76   LEU I CG  1 
ATOM   3042 C CD1 . LEU C 3  84  ? -2.842  7.485   12.602  1.00 53.16 ? 76   LEU I CD1 1 
ATOM   3043 C CD2 . LEU C 3  84  ? -1.804  7.375   10.331  1.00 52.48 ? 76   LEU I CD2 1 
ATOM   3044 N N   . GLY C 3  85  ? -1.546  12.878  10.548  1.00 55.79 ? 77   GLY I N   1 
ATOM   3045 C CA  . GLY C 3  85  ? -2.125  14.195  10.365  1.00 56.82 ? 77   GLY I CA  1 
ATOM   3046 C C   . GLY C 3  85  ? -3.483  14.301  11.027  1.00 57.83 ? 77   GLY I C   1 
ATOM   3047 O O   . GLY C 3  85  ? -4.469  14.657  10.381  1.00 58.20 ? 77   GLY I O   1 
ATOM   3048 N N   . LEU C 3  86  ? -3.537  13.989  12.319  1.00 58.39 ? 78   LEU I N   1 
ATOM   3049 C CA  . LEU C 3  86  ? -4.786  14.046  13.069  1.00 58.91 ? 78   LEU I CA  1 
ATOM   3050 C C   . LEU C 3  86  ? -4.742  15.196  14.070  1.00 58.91 ? 78   LEU I C   1 
ATOM   3051 O O   . LEU C 3  86  ? -5.053  16.338  13.732  1.00 59.39 ? 78   LEU I O   1 
ATOM   3052 C CB  . LEU C 3  86  ? -5.015  12.723  13.807  1.00 59.46 ? 78   LEU I CB  1 
ATOM   3053 C CG  . LEU C 3  86  ? -6.438  12.367  14.256  1.00 60.52 ? 78   LEU I CG  1 
ATOM   3054 C CD1 . LEU C 3  86  ? -6.968  13.403  15.234  1.00 61.00 ? 78   LEU I CD1 1 
ATOM   3055 C CD2 . LEU C 3  86  ? -7.338  12.273  13.034  1.00 61.15 ? 78   LEU I CD2 1 
ATOM   3056 N N   . SER C 3  91  ? -9.157  16.461  14.567  1.00 65.46 ? 83   SER I N   1 
ATOM   3057 C CA  . SER C 3  91  ? -10.545 16.087  14.810  1.00 65.45 ? 83   SER I CA  1 
ATOM   3058 C C   . SER C 3  91  ? -10.709 15.465  16.192  1.00 65.39 ? 83   SER I C   1 
ATOM   3059 O O   . SER C 3  91  ? -11.019 16.157  17.162  1.00 65.57 ? 83   SER I O   1 
ATOM   3060 C CB  . SER C 3  91  ? -11.020 15.100  13.740  1.00 65.45 ? 83   SER I CB  1 
ATOM   3061 N N   . SER C 3  92  ? -10.496 14.156  16.277  1.00 65.03 ? 84   SER I N   1 
ATOM   3062 C CA  . SER C 3  92  ? -10.622 13.437  17.539  1.00 64.68 ? 84   SER I CA  1 
ATOM   3063 C C   . SER C 3  92  ? -10.152 11.995  17.396  1.00 64.13 ? 84   SER I C   1 
ATOM   3064 O O   . SER C 3  92  ? -10.335 11.374  16.348  1.00 64.20 ? 84   SER I O   1 
ATOM   3065 C CB  . SER C 3  92  ? -12.079 13.451  18.009  1.00 64.72 ? 84   SER I CB  1 
ATOM   3066 O OG  . SER C 3  92  ? -12.244 12.672  19.181  1.00 65.29 ? 84   SER I OG  1 
ATOM   3067 N N   . GLU C 3  93  ? -9.544  11.465  18.453  1.00 63.23 ? 85   GLU I N   1 
ATOM   3068 C CA  . GLU C 3  93  ? -9.062  10.091  18.436  1.00 62.19 ? 85   GLU I CA  1 
ATOM   3069 C C   . GLU C 3  93  ? -10.236 9.132   18.290  1.00 61.06 ? 85   GLU I C   1 
ATOM   3070 O O   . GLU C 3  93  ? -10.225 8.247   17.433  1.00 60.60 ? 85   GLU I O   1 
ATOM   3071 C CB  . GLU C 3  93  ? -8.295  9.775   19.722  1.00 62.81 ? 85   GLU I CB  1 
ATOM   3072 C CG  . GLU C 3  93  ? -6.960  10.488  19.844  1.00 63.56 ? 85   GLU I CG  1 
ATOM   3073 C CD  . GLU C 3  93  ? -6.209  10.100  21.102  1.00 64.22 ? 85   GLU I CD  1 
ATOM   3074 O OE1 . GLU C 3  93  ? -5.979  8.889   21.308  1.00 64.29 ? 85   GLU I OE1 1 
ATOM   3075 O OE2 . GLU C 3  93  ? -5.846  11.005  21.884  1.00 64.97 ? 85   GLU I OE2 1 
ATOM   3076 N N   . LYS C 3  94  ? -11.248 9.314   19.133  1.00 59.59 ? 86   LYS I N   1 
ATOM   3077 C CA  . LYS C 3  94  ? -12.433 8.468   19.099  1.00 58.20 ? 86   LYS I CA  1 
ATOM   3078 C C   . LYS C 3  94  ? -13.006 8.425   17.688  1.00 56.95 ? 86   LYS I C   1 
ATOM   3079 O O   . LYS C 3  94  ? -13.462 7.380   17.225  1.00 57.43 ? 86   LYS I O   1 
ATOM   3080 C CB  . LYS C 3  94  ? -13.491 8.998   20.071  1.00 58.05 ? 86   LYS I CB  1 
ATOM   3081 N N   . GLU C 3  95  ? -12.976 9.568   17.009  1.00 55.25 ? 87   GLU I N   1 
ATOM   3082 C CA  . GLU C 3  95  ? -13.486 9.661   15.647  1.00 53.45 ? 87   GLU I CA  1 
ATOM   3083 C C   . GLU C 3  95  ? -12.561 8.915   14.692  1.00 52.04 ? 87   GLU I C   1 
ATOM   3084 O O   . GLU C 3  95  ? -13.016 8.194   13.803  1.00 52.11 ? 87   GLU I O   1 
ATOM   3085 C CB  . GLU C 3  95  ? -13.595 11.128  15.222  1.00 54.38 ? 87   GLU I CB  1 
ATOM   3086 N N   . LEU C 3  96  ? -11.259 9.094   14.884  1.00 50.15 ? 88   LEU I N   1 
ATOM   3087 C CA  . LEU C 3  96  ? -10.262 8.439   14.047  1.00 48.52 ? 88   LEU I CA  1 
ATOM   3088 C C   . LEU C 3  96  ? -10.467 6.928   14.043  1.00 46.68 ? 88   LEU I C   1 
ATOM   3089 O O   . LEU C 3  96  ? -10.589 6.310   12.985  1.00 46.32 ? 88   LEU I O   1 
ATOM   3090 C CB  . LEU C 3  96  ? -8.853  8.762   14.555  1.00 48.93 ? 88   LEU I CB  1 
ATOM   3091 C CG  . LEU C 3  96  ? -7.683  8.112   13.810  1.00 49.55 ? 88   LEU I CG  1 
ATOM   3092 C CD1 . LEU C 3  96  ? -7.628  8.628   12.380  1.00 49.55 ? 88   LEU I CD1 1 
ATOM   3093 C CD2 . LEU C 3  96  ? -6.385  8.420   14.535  1.00 49.54 ? 88   LEU I CD2 1 
ATOM   3094 N N   . HIS C 3  97  ? -10.508 6.340   15.235  1.00 45.07 ? 89   HIS I N   1 
ATOM   3095 C CA  . HIS C 3  97  ? -10.686 4.900   15.377  1.00 43.75 ? 89   HIS I CA  1 
ATOM   3096 C C   . HIS C 3  97  ? -12.054 4.437   14.885  1.00 43.55 ? 89   HIS I C   1 
ATOM   3097 O O   . HIS C 3  97  ? -12.183 3.353   14.313  1.00 42.29 ? 89   HIS I O   1 
ATOM   3098 C CB  . HIS C 3  97  ? -10.487 4.496   16.840  1.00 42.61 ? 89   HIS I CB  1 
ATOM   3099 C CG  . HIS C 3  97  ? -9.136  4.848   17.381  1.00 41.19 ? 89   HIS I CG  1 
ATOM   3100 N ND1 . HIS C 3  97  ? -7.971  4.310   16.878  1.00 40.54 ? 89   HIS I ND1 1 
ATOM   3101 C CD2 . HIS C 3  97  ? -8.761  5.709   18.356  1.00 40.74 ? 89   HIS I CD2 1 
ATOM   3102 C CE1 . HIS C 3  97  ? -6.937  4.825   17.518  1.00 40.12 ? 89   HIS I CE1 1 
ATOM   3103 N NE2 . HIS C 3  97  ? -7.389  5.677   18.421  1.00 39.54 ? 89   HIS I NE2 1 
ATOM   3104 N N   . ARG C 3  98  ? -13.073 5.259   15.109  1.00 43.95 ? 90   ARG I N   1 
ATOM   3105 C CA  . ARG C 3  98  ? -14.422 4.921   14.672  1.00 44.26 ? 90   ARG I CA  1 
ATOM   3106 C C   . ARG C 3  98  ? -14.429 4.790   13.153  1.00 43.55 ? 90   ARG I C   1 
ATOM   3107 O O   . ARG C 3  98  ? -14.977 3.835   12.601  1.00 44.30 ? 90   ARG I O   1 
ATOM   3108 C CB  . ARG C 3  98  ? -15.409 6.008   15.106  1.00 44.70 ? 90   ARG I CB  1 
ATOM   3109 N N   . GLY C 3  99  ? -13.805 5.756   12.486  1.00 43.54 ? 91   GLY I N   1 
ATOM   3110 C CA  . GLY C 3  99  ? -13.739 5.740   11.037  1.00 42.25 ? 91   GLY I CA  1 
ATOM   3111 C C   . GLY C 3  99  ? -13.135 4.457   10.500  1.00 41.82 ? 91   GLY I C   1 
ATOM   3112 O O   . GLY C 3  99  ? -13.730 3.797   9.647   1.00 41.39 ? 91   GLY I O   1 
ATOM   3113 N N   . PHE C 3  100 ? -11.955 4.098   10.999  1.00 40.75 ? 92   PHE I N   1 
ATOM   3114 C CA  . PHE C 3  100 ? -11.280 2.882   10.556  1.00 39.81 ? 92   PHE I CA  1 
ATOM   3115 C C   . PHE C 3  100 ? -12.073 1.632   10.902  1.00 39.16 ? 92   PHE I C   1 
ATOM   3116 O O   . PHE C 3  100 ? -12.082 0.668   10.137  1.00 39.40 ? 92   PHE I O   1 
ATOM   3117 C CB  . PHE C 3  100 ? -9.878  2.789   11.168  1.00 39.11 ? 92   PHE I CB  1 
ATOM   3118 C CG  . PHE C 3  100 ? -8.898  3.774   10.593  1.00 39.45 ? 92   PHE I CG  1 
ATOM   3119 C CD1 . PHE C 3  100 ? -8.668  3.825   9.222   1.00 39.93 ? 92   PHE I CD1 1 
ATOM   3120 C CD2 . PHE C 3  100 ? -8.195  4.643   11.422  1.00 39.45 ? 92   PHE I CD2 1 
ATOM   3121 C CE1 . PHE C 3  100 ? -7.750  4.727   8.684   1.00 40.69 ? 92   PHE I CE1 1 
ATOM   3122 C CE2 . PHE C 3  100 ? -7.276  5.548   10.894  1.00 39.33 ? 92   PHE I CE2 1 
ATOM   3123 C CZ  . PHE C 3  100 ? -7.053  5.590   9.522   1.00 39.93 ? 92   PHE I CZ  1 
ATOM   3124 N N   . GLN C 3  101 ? -12.734 1.643   12.056  1.00 38.98 ? 93   GLN I N   1 
ATOM   3125 C CA  . GLN C 3  101 ? -13.533 0.496   12.466  1.00 39.15 ? 93   GLN I CA  1 
ATOM   3126 C C   . GLN C 3  101 ? -14.604 0.248   11.414  1.00 39.19 ? 93   GLN I C   1 
ATOM   3127 O O   . GLN C 3  101 ? -14.768 -0.869  10.928  1.00 38.05 ? 93   GLN I O   1 
ATOM   3128 C CB  . GLN C 3  101 ? -14.197 0.756   13.821  1.00 38.67 ? 93   GLN I CB  1 
ATOM   3129 C CG  . GLN C 3  101 ? -15.201 -0.318  14.221  1.00 38.89 ? 93   GLN I CG  1 
ATOM   3130 C CD  . GLN C 3  101 ? -15.806 -0.078  15.588  1.00 39.89 ? 93   GLN I CD  1 
ATOM   3131 O OE1 . GLN C 3  101 ? -16.333 1.000   15.867  1.00 39.62 ? 93   GLN I OE1 1 
ATOM   3132 N NE2 . GLN C 3  101 ? -15.738 -1.086  16.450  1.00 39.48 ? 93   GLN I NE2 1 
ATOM   3133 N N   . GLN C 3  102 ? -15.328 1.306   11.066  1.00 40.38 ? 94   GLN I N   1 
ATOM   3134 C CA  . GLN C 3  102 ? -16.385 1.219   10.068  1.00 42.49 ? 94   GLN I CA  1 
ATOM   3135 C C   . GLN C 3  102 ? -15.799 0.851   8.710   1.00 42.94 ? 94   GLN I C   1 
ATOM   3136 O O   . GLN C 3  102 ? -16.259 -0.083  8.053   1.00 42.82 ? 94   GLN I O   1 
ATOM   3137 C CB  . GLN C 3  102 ? -17.115 2.558   9.969   1.00 43.81 ? 94   GLN I CB  1 
ATOM   3138 C CG  . GLN C 3  102 ? -18.228 2.582   8.939   1.00 46.92 ? 94   GLN I CG  1 
ATOM   3139 C CD  . GLN C 3  102 ? -18.886 3.941   8.835   1.00 48.40 ? 94   GLN I CD  1 
ATOM   3140 O OE1 . GLN C 3  102 ? -19.383 4.481   9.825   1.00 50.14 ? 94   GLN I OE1 1 
ATOM   3141 N NE2 . GLN C 3  102 ? -18.894 4.505   7.632   1.00 49.22 ? 94   GLN I NE2 1 
ATOM   3142 N N   . LEU C 3  103 ? -14.777 1.596   8.301   1.00 44.05 ? 95   LEU I N   1 
ATOM   3143 C CA  . LEU C 3  103 ? -14.112 1.368   7.024   1.00 45.31 ? 95   LEU I CA  1 
ATOM   3144 C C   . LEU C 3  103 ? -13.663 -0.084  6.907   1.00 46.35 ? 95   LEU I C   1 
ATOM   3145 O O   . LEU C 3  103 ? -13.763 -0.692  5.841   1.00 46.42 ? 95   LEU I O   1 
ATOM   3146 C CB  . LEU C 3  103 ? -12.907 2.308   6.897   1.00 45.89 ? 95   LEU I CB  1 
ATOM   3147 C CG  . LEU C 3  103 ? -12.099 2.333   5.595   1.00 47.10 ? 95   LEU I CG  1 
ATOM   3148 C CD1 . LEU C 3  103 ? -11.216 3.572   5.573   1.00 47.37 ? 95   LEU I CD1 1 
ATOM   3149 C CD2 . LEU C 3  103 ? -11.257 1.076   5.470   1.00 47.13 ? 95   LEU I CD2 1 
ATOM   3150 N N   . LEU C 3  104 ? -13.172 -0.635  8.011   1.00 47.36 ? 96   LEU I N   1 
ATOM   3151 C CA  . LEU C 3  104 ? -12.699 -2.012  8.037   1.00 48.32 ? 96   LEU I CA  1 
ATOM   3152 C C   . LEU C 3  104 ? -13.872 -2.980  7.936   1.00 50.01 ? 96   LEU I C   1 
ATOM   3153 O O   . LEU C 3  104 ? -13.723 -4.105  7.456   1.00 50.33 ? 96   LEU I O   1 
ATOM   3154 C CB  . LEU C 3  104 ? -11.914 -2.268  9.327   1.00 48.13 ? 96   LEU I CB  1 
ATOM   3155 C CG  . LEU C 3  104 ? -11.140 -3.582  9.432   1.00 47.79 ? 96   LEU I CG  1 
ATOM   3156 C CD1 . LEU C 3  104 ? -10.130 -3.683  8.297   1.00 46.63 ? 96   LEU I CD1 1 
ATOM   3157 C CD2 . LEU C 3  104 ? -10.435 -3.643  10.778  1.00 47.33 ? 96   LEU I CD2 1 
ATOM   3158 N N   . GLN C 3  105 ? -15.039 -2.537  8.394   1.00 51.93 ? 97   GLN I N   1 
ATOM   3159 C CA  . GLN C 3  105 ? -16.245 -3.356  8.342   1.00 53.72 ? 97   GLN I CA  1 
ATOM   3160 C C   . GLN C 3  105 ? -16.739 -3.414  6.903   1.00 54.68 ? 97   GLN I C   1 
ATOM   3161 O O   . GLN C 3  105 ? -17.111 -4.475  6.401   1.00 54.61 ? 97   GLN I O   1 
ATOM   3162 C CB  . GLN C 3  105 ? -17.334 -2.756  9.236   1.00 53.48 ? 97   GLN I CB  1 
ATOM   3163 C CG  . GLN C 3  105 ? -16.999 -2.765  10.719  1.00 54.76 ? 97   GLN I CG  1 
ATOM   3164 C CD  . GLN C 3  105 ? -18.032 -2.037  11.561  1.00 54.83 ? 97   GLN I CD  1 
ATOM   3165 O OE1 . GLN C 3  105 ? -17.923 -1.982  12.786  1.00 54.55 ? 97   GLN I OE1 1 
ATOM   3166 N NE2 . GLN C 3  105 ? -19.040 -1.471  10.905  1.00 55.39 ? 97   GLN I NE2 1 
ATOM   3167 N N   . GLU C 3  106 ? -16.734 -2.259  6.246   1.00 56.06 ? 98   GLU I N   1 
ATOM   3168 C CA  . GLU C 3  106 ? -17.177 -2.153  4.861   1.00 57.68 ? 98   GLU I CA  1 
ATOM   3169 C C   . GLU C 3  106 ? -16.308 -3.005  3.942   1.00 58.50 ? 98   GLU I C   1 
ATOM   3170 O O   . GLU C 3  106 ? -16.819 -3.798  3.152   1.00 58.69 ? 98   GLU I O   1 
ATOM   3171 C CB  . GLU C 3  106 ? -17.129 -0.692  4.414   1.00 57.94 ? 98   GLU I CB  1 
ATOM   3172 C CG  . GLU C 3  106 ? -18.039 0.220   5.219   1.00 58.71 ? 98   GLU I CG  1 
ATOM   3173 C CD  . GLU C 3  106 ? -17.821 1.686   4.906   1.00 58.97 ? 98   GLU I CD  1 
ATOM   3174 O OE1 . GLU C 3  106 ? -18.565 2.529   5.450   1.00 59.34 ? 98   GLU I OE1 1 
ATOM   3175 O OE2 . GLU C 3  106 ? -16.901 1.995   4.120   1.00 59.56 ? 98   GLU I OE2 1 
ATOM   3176 N N   . LEU C 3  107 ? -14.992 -2.839  4.052   1.00 59.31 ? 99   LEU I N   1 
ATOM   3177 C CA  . LEU C 3  107 ? -14.060 -3.601  3.229   1.00 60.06 ? 99   LEU I CA  1 
ATOM   3178 C C   . LEU C 3  107 ? -14.162 -5.089  3.547   1.00 61.12 ? 99   LEU I C   1 
ATOM   3179 O O   . LEU C 3  107 ? -13.578 -5.924  2.855   1.00 61.22 ? 99   LEU I O   1 
ATOM   3180 C CB  . LEU C 3  107 ? -12.624 -3.124  3.468   1.00 59.33 ? 99   LEU I CB  1 
ATOM   3181 C CG  . LEU C 3  107 ? -12.302 -1.660  3.158   1.00 58.79 ? 99   LEU I CG  1 
ATOM   3182 C CD1 . LEU C 3  107 ? -10.820 -1.418  3.384   1.00 58.65 ? 99   LEU I CD1 1 
ATOM   3183 C CD2 . LEU C 3  107 ? -12.675 -1.332  1.721   1.00 59.00 ? 99   LEU I CD2 1 
ATOM   3184 N N   . ASN C 3  108 ? -14.907 -5.412  4.600   1.00 62.24 ? 100  ASN I N   1 
ATOM   3185 C CA  . ASN C 3  108 ? -15.094 -6.797  5.017   1.00 63.25 ? 100  ASN I CA  1 
ATOM   3186 C C   . ASN C 3  108 ? -16.327 -7.399  4.351   1.00 63.88 ? 100  ASN I C   1 
ATOM   3187 O O   . ASN C 3  108 ? -16.489 -8.620  4.315   1.00 63.94 ? 100  ASN I O   1 
ATOM   3188 C CB  . ASN C 3  108 ? -15.241 -6.876  6.538   1.00 63.78 ? 100  ASN I CB  1 
ATOM   3189 N N   . GLN C 3  109 ? -17.198 -6.538  3.834   1.00 64.38 ? 101  GLN I N   1 
ATOM   3190 C CA  . GLN C 3  109 ? -18.408 -6.993  3.160   1.00 65.14 ? 101  GLN I CA  1 
ATOM   3191 C C   . GLN C 3  109 ? -18.011 -7.588  1.813   1.00 65.67 ? 101  GLN I C   1 
ATOM   3192 O O   . GLN C 3  109 ? -17.623 -6.863  0.896   1.00 65.77 ? 101  GLN I O   1 
ATOM   3193 C CB  . GLN C 3  109 ? -19.372 -5.823  2.950   1.00 64.85 ? 101  GLN I CB  1 
ATOM   3194 N N   . PRO C 3  110 ? -18.104 -8.920  1.678   1.00 66.10 ? 102  PRO I N   1 
ATOM   3195 C CA  . PRO C 3  110 ? -17.749 -9.616  0.437   1.00 66.69 ? 102  PRO I CA  1 
ATOM   3196 C C   . PRO C 3  110 ? -18.506 -9.134  -0.799  1.00 67.35 ? 102  PRO I C   1 
ATOM   3197 O O   . PRO C 3  110 ? -19.476 -9.758  -1.230  1.00 68.00 ? 102  PRO I O   1 
ATOM   3198 C CB  . PRO C 3  110 ? -18.039 -11.079 0.769   1.00 66.32 ? 102  PRO I CB  1 
ATOM   3199 C CG  . PRO C 3  110 ? -19.160 -10.981 1.752   1.00 66.15 ? 102  PRO I CG  1 
ATOM   3200 C CD  . PRO C 3  110 ? -18.696 -9.859  2.647   1.00 65.95 ? 102  PRO I CD  1 
ATOM   3201 N N   . ARG C 3  111 ? -18.050 -8.021  -1.365  1.00 67.67 ? 103  ARG I N   1 
ATOM   3202 C CA  . ARG C 3  111 ? -18.666 -7.452  -2.557  1.00 68.10 ? 103  ARG I CA  1 
ATOM   3203 C C   . ARG C 3  111 ? -18.264 -8.312  -3.754  1.00 68.29 ? 103  ARG I C   1 
ATOM   3204 O O   . ARG C 3  111 ? -17.175 -8.145  -4.302  1.00 68.64 ? 103  ARG I O   1 
ATOM   3205 C CB  . ARG C 3  111 ? -18.181 -6.011  -2.752  1.00 67.96 ? 103  ARG I CB  1 
ATOM   3206 C CG  . ARG C 3  111 ? -18.836 -5.267  -3.905  1.00 68.37 ? 103  ARG I CG  1 
ATOM   3207 C CD  . ARG C 3  111 ? -18.345 -3.827  -3.979  1.00 68.18 ? 103  ARG I CD  1 
ATOM   3208 N N   . ASP C 3  112 ? -19.142 -9.233  -4.145  1.00 68.22 ? 104  ASP I N   1 
ATOM   3209 C CA  . ASP C 3  112 ? -18.871 -10.132 -5.266  1.00 68.22 ? 104  ASP I CA  1 
ATOM   3210 C C   . ASP C 3  112 ? -18.551 -9.403  -6.568  1.00 67.56 ? 104  ASP I C   1 
ATOM   3211 O O   . ASP C 3  112 ? -19.349 -9.371  -7.503  1.00 68.10 ? 104  ASP I O   1 
ATOM   3212 C CB  . ASP C 3  112 ? -20.047 -11.096 -5.474  1.00 68.87 ? 104  ASP I CB  1 
ATOM   3213 C CG  . ASP C 3  112 ? -21.390 -10.395 -5.467  1.00 69.50 ? 104  ASP I CG  1 
ATOM   3214 O OD1 . ASP C 3  112 ? -21.599 -9.490  -6.303  1.00 70.30 ? 104  ASP I OD1 1 
ATOM   3215 O OD2 . ASP C 3  112 ? -22.241 -10.753 -4.625  1.00 69.81 ? 104  ASP I OD2 1 
ATOM   3216 N N   . GLY C 3  113 ? -17.355 -8.829  -6.605  1.00 66.75 ? 105  GLY I N   1 
ATOM   3217 C CA  . GLY C 3  113 ? -16.879 -8.094  -7.759  1.00 65.14 ? 105  GLY I CA  1 
ATOM   3218 C C   . GLY C 3  113 ? -15.463 -7.684  -7.416  1.00 64.25 ? 105  GLY I C   1 
ATOM   3219 O O   . GLY C 3  113 ? -14.733 -7.124  -8.236  1.00 63.86 ? 105  GLY I O   1 
ATOM   3220 N N   . PHE C 3  114 ? -15.087 -7.975  -6.173  1.00 63.11 ? 106  PHE I N   1 
ATOM   3221 C CA  . PHE C 3  114 ? -13.763 -7.666  -5.652  1.00 62.10 ? 106  PHE I CA  1 
ATOM   3222 C C   . PHE C 3  114 ? -13.182 -8.856  -4.897  1.00 61.16 ? 106  PHE I C   1 
ATOM   3223 O O   . PHE C 3  114 ? -13.897 -9.781  -4.513  1.00 61.34 ? 106  PHE I O   1 
ATOM   3224 C CB  . PHE C 3  114 ? -13.820 -6.481  -4.680  1.00 62.28 ? 106  PHE I CB  1 
ATOM   3225 C CG  . PHE C 3  114 ? -14.159 -5.169  -5.323  1.00 62.60 ? 106  PHE I CG  1 
ATOM   3226 C CD1 . PHE C 3  114 ? -15.419 -4.945  -5.864  1.00 62.78 ? 106  PHE I CD1 1 
ATOM   3227 C CD2 . PHE C 3  114 ? -13.218 -4.144  -5.368  1.00 62.66 ? 106  PHE I CD2 1 
ATOM   3228 C CE1 . PHE C 3  114 ? -15.738 -3.720  -6.440  1.00 62.93 ? 106  PHE I CE1 1 
ATOM   3229 C CE2 . PHE C 3  114 ? -13.526 -2.914  -5.943  1.00 62.41 ? 106  PHE I CE2 1 
ATOM   3230 C CZ  . PHE C 3  114 ? -14.789 -2.701  -6.480  1.00 62.84 ? 106  PHE I CZ  1 
ATOM   3231 N N   . GLN C 3  115 ? -11.872 -8.812  -4.695  1.00 59.99 ? 107  GLN I N   1 
ATOM   3232 C CA  . GLN C 3  115 ? -11.148 -9.832  -3.949  1.00 59.01 ? 107  GLN I CA  1 
ATOM   3233 C C   . GLN C 3  115 ? -10.240 -9.031  -3.029  1.00 57.49 ? 107  GLN I C   1 
ATOM   3234 O O   . GLN C 3  115 ? -9.107  -8.709  -3.390  1.00 57.69 ? 107  GLN I O   1 
ATOM   3235 C CB  . GLN C 3  115 ? -10.308 -10.710 -4.879  1.00 60.00 ? 107  GLN I CB  1 
ATOM   3236 C CG  . GLN C 3  115 ? -11.113 -11.658 -5.751  1.00 61.72 ? 107  GLN I CG  1 
ATOM   3237 C CD  . GLN C 3  115 ? -10.232 -12.630 -6.514  1.00 62.74 ? 107  GLN I CD  1 
ATOM   3238 O OE1 . GLN C 3  115 ? -9.418  -12.227 -7.345  1.00 63.58 ? 107  GLN I OE1 1 
ATOM   3239 N NE2 . GLN C 3  115 ? -10.388 -13.918 -6.230  1.00 63.60 ? 107  GLN I NE2 1 
ATOM   3240 N N   . LEU C 3  116 ? -10.749 -8.695  -1.848  1.00 55.48 ? 108  LEU I N   1 
ATOM   3241 C CA  . LEU C 3  116 ? -9.989  -7.901  -0.894  1.00 53.45 ? 108  LEU I CA  1 
ATOM   3242 C C   . LEU C 3  116 ? -9.794  -8.580  0.455   1.00 51.99 ? 108  LEU I C   1 
ATOM   3243 O O   . LEU C 3  116 ? -10.757 -8.880  1.161   1.00 51.71 ? 108  LEU I O   1 
ATOM   3244 C CB  . LEU C 3  116 ? -10.674 -6.543  -0.702  1.00 53.91 ? 108  LEU I CB  1 
ATOM   3245 C CG  . LEU C 3  116 ? -10.046 -5.512  0.241   1.00 54.59 ? 108  LEU I CG  1 
ATOM   3246 C CD1 . LEU C 3  116 ? -10.622 -4.139  -0.066  1.00 54.52 ? 108  LEU I CD1 1 
ATOM   3247 C CD2 . LEU C 3  116 ? -10.304 -5.891  1.692   1.00 54.95 ? 108  LEU I CD2 1 
ATOM   3248 N N   . SER C 3  117 ? -8.533  -8.812  0.804   1.00 49.93 ? 109  SER I N   1 
ATOM   3249 C CA  . SER C 3  117 ? -8.181  -9.435  2.072   1.00 47.82 ? 109  SER I CA  1 
ATOM   3250 C C   . SER C 3  117 ? -7.279  -8.480  2.841   1.00 46.20 ? 109  SER I C   1 
ATOM   3251 O O   . SER C 3  117 ? -6.104  -8.323  2.511   1.00 45.51 ? 109  SER I O   1 
ATOM   3252 C CB  . SER C 3  117 ? -7.448  -10.757 1.837   1.00 48.09 ? 109  SER I CB  1 
ATOM   3253 O OG  . SER C 3  117 ? -8.261  -11.671 1.126   1.00 50.43 ? 109  SER I OG  1 
ATOM   3254 N N   . LEU C 3  118 ? -7.842  -7.835  3.857   1.00 44.10 ? 110  LEU I N   1 
ATOM   3255 C CA  . LEU C 3  118 ? -7.099  -6.892  4.682   1.00 41.75 ? 110  LEU I CA  1 
ATOM   3256 C C   . LEU C 3  118 ? -6.988  -7.444  6.099   1.00 40.36 ? 110  LEU I C   1 
ATOM   3257 O O   . LEU C 3  118 ? -7.975  -7.910  6.668   1.00 40.07 ? 110  LEU I O   1 
ATOM   3258 C CB  . LEU C 3  118 ? -7.814  -5.539  4.697   1.00 42.34 ? 110  LEU I CB  1 
ATOM   3259 C CG  . LEU C 3  118 ? -7.241  -4.438  5.591   1.00 43.78 ? 110  LEU I CG  1 
ATOM   3260 C CD1 . LEU C 3  118 ? -5.767  -4.211  5.273   1.00 44.58 ? 110  LEU I CD1 1 
ATOM   3261 C CD2 . LEU C 3  118 ? -8.041  -3.163  5.380   1.00 44.40 ? 110  LEU I CD2 1 
ATOM   3262 N N   . GLY C 3  119 ? -5.785  -7.395  6.666   1.00 37.83 ? 111  GLY I N   1 
ATOM   3263 C CA  . GLY C 3  119 ? -5.596  -7.912  8.008   1.00 35.21 ? 111  GLY I CA  1 
ATOM   3264 C C   . GLY C 3  119 ? -4.527  -7.216  8.827   1.00 33.61 ? 111  GLY I C   1 
ATOM   3265 O O   . GLY C 3  119 ? -3.613  -6.586  8.292   1.00 30.91 ? 111  GLY I O   1 
ATOM   3266 N N   . ASN C 3  120 ? -4.651  -7.347  10.143  1.00 32.42 ? 112  ASN I N   1 
ATOM   3267 C CA  . ASN C 3  120 ? -3.721  -6.747  11.090  1.00 31.69 ? 112  ASN I CA  1 
ATOM   3268 C C   . ASN C 3  120 ? -3.555  -7.701  12.264  1.00 31.27 ? 112  ASN I C   1 
ATOM   3269 O O   . ASN C 3  120 ? -4.523  -8.313  12.712  1.00 30.09 ? 112  ASN I O   1 
ATOM   3270 C CB  . ASN C 3  120 ? -4.276  -5.419  11.602  1.00 32.20 ? 112  ASN I CB  1 
ATOM   3271 C CG  . ASN C 3  120 ? -4.247  -4.330  10.552  1.00 35.25 ? 112  ASN I CG  1 
ATOM   3272 O OD1 . ASN C 3  120 ? -3.192  -3.767  10.255  1.00 36.17 ? 112  ASN I OD1 1 
ATOM   3273 N ND2 . ASN C 3  120 ? -5.407  -4.029  9.980   1.00 34.52 ? 112  ASN I ND2 1 
ATOM   3274 N N   . ALA C 3  121 ? -2.330  -7.830  12.759  1.00 30.61 ? 113  ALA I N   1 
ATOM   3275 C CA  . ALA C 3  121 ? -2.072  -8.713  13.888  1.00 29.48 ? 113  ALA I CA  1 
ATOM   3276 C C   . ALA C 3  121 ? -0.772  -8.350  14.585  1.00 29.12 ? 113  ALA I C   1 
ATOM   3277 O O   . ALA C 3  121 ? 0.178   -7.894  13.953  1.00 28.03 ? 113  ALA I O   1 
ATOM   3278 C CB  . ALA C 3  121 ? -2.021  -10.160 13.419  1.00 28.52 ? 113  ALA I CB  1 
ATOM   3279 N N   . LEU C 3  122 ? -0.741  -8.552  15.896  1.00 27.71 ? 114  LEU I N   1 
ATOM   3280 C CA  . LEU C 3  122 ? 0.451   -8.268  16.682  1.00 29.36 ? 114  LEU I CA  1 
ATOM   3281 C C   . LEU C 3  122 ? 0.951   -9.556  17.304  1.00 28.00 ? 114  LEU I C   1 
ATOM   3282 O O   . LEU C 3  122 ? 0.175   -10.322 17.872  1.00 29.91 ? 114  LEU I O   1 
ATOM   3283 C CB  . LEU C 3  122 ? 0.148   -7.260  17.795  1.00 30.52 ? 114  LEU I CB  1 
ATOM   3284 C CG  . LEU C 3  122 ? 0.585   -5.810  17.573  1.00 34.02 ? 114  LEU I CG  1 
ATOM   3285 C CD1 . LEU C 3  122 ? -0.112  -5.239  16.351  1.00 36.21 ? 114  LEU I CD1 1 
ATOM   3286 C CD2 . LEU C 3  122 ? 0.255   -4.984  18.811  1.00 37.08 ? 114  LEU I CD2 1 
ATOM   3287 N N   . PHE C 3  123 ? 2.248   -9.803  17.171  1.00 27.47 ? 115  PHE I N   1 
ATOM   3288 C CA  . PHE C 3  123 ? 2.859   -10.986 17.753  1.00 27.12 ? 115  PHE I CA  1 
ATOM   3289 C C   . PHE C 3  123 ? 3.783   -10.481 18.842  1.00 25.72 ? 115  PHE I C   1 
ATOM   3290 O O   . PHE C 3  123 ? 4.722   -9.732  18.580  1.00 25.72 ? 115  PHE I O   1 
ATOM   3291 C CB  . PHE C 3  123 ? 3.630   -11.773 16.696  1.00 27.76 ? 115  PHE I CB  1 
ATOM   3292 C CG  . PHE C 3  123 ? 2.750   -12.353 15.632  1.00 29.82 ? 115  PHE I CG  1 
ATOM   3293 C CD1 . PHE C 3  123 ? 2.230   -11.544 14.626  1.00 30.00 ? 115  PHE I CD1 1 
ATOM   3294 C CD2 . PHE C 3  123 ? 2.393   -13.697 15.664  1.00 31.14 ? 115  PHE I CD2 1 
ATOM   3295 C CE1 . PHE C 3  123 ? 1.363   -12.065 13.668  1.00 30.85 ? 115  PHE I CE1 1 
ATOM   3296 C CE2 . PHE C 3  123 ? 1.526   -14.228 14.711  1.00 32.09 ? 115  PHE I CE2 1 
ATOM   3297 C CZ  . PHE C 3  123 ? 1.011   -13.408 13.711  1.00 30.81 ? 115  PHE I CZ  1 
ATOM   3298 N N   . THR C 3  124 ? 3.503   -10.891 20.073  1.00 25.94 ? 116  THR I N   1 
ATOM   3299 C CA  . THR C 3  124 ? 4.275   -10.436 21.217  1.00 25.89 ? 116  THR I CA  1 
ATOM   3300 C C   . THR C 3  124 ? 5.030   -11.561 21.913  1.00 26.12 ? 116  THR I C   1 
ATOM   3301 O O   . THR C 3  124 ? 4.492   -12.650 22.107  1.00 25.91 ? 116  THR I O   1 
ATOM   3302 C CB  . THR C 3  124 ? 3.339   -9.742  22.231  1.00 26.15 ? 116  THR I CB  1 
ATOM   3303 O OG1 . THR C 3  124 ? 2.292   -10.647 22.609  1.00 26.90 ? 116  THR I OG1 1 
ATOM   3304 C CG2 . THR C 3  124 ? 2.706   -8.504  21.605  1.00 25.01 ? 116  THR I CG2 1 
ATOM   3305 N N   . ASP C 3  125 ? 6.279   -11.293 22.286  1.00 25.87 ? 117  ASP I N   1 
ATOM   3306 C CA  . ASP C 3  125 ? 7.100   -12.291 22.964  1.00 27.57 ? 117  ASP I CA  1 
ATOM   3307 C C   . ASP C 3  125 ? 6.336   -12.835 24.170  1.00 27.08 ? 117  ASP I C   1 
ATOM   3308 O O   . ASP C 3  125 ? 5.608   -12.102 24.841  1.00 25.69 ? 117  ASP I O   1 
ATOM   3309 C CB  . ASP C 3  125 ? 8.422   -11.671 23.426  1.00 29.46 ? 117  ASP I CB  1 
ATOM   3310 C CG  . ASP C 3  125 ? 9.511   -12.710 23.651  1.00 32.09 ? 117  ASP I CG  1 
ATOM   3311 O OD1 . ASP C 3  125 ? 10.559  -12.351 24.224  1.00 34.89 ? 117  ASP I OD1 1 
ATOM   3312 O OD2 . ASP C 3  125 ? 9.330   -13.879 23.248  1.00 33.58 ? 117  ASP I OD2 1 
ATOM   3313 N N   . LEU C 3  126 ? 6.508   -14.126 24.431  1.00 28.34 ? 118  LEU I N   1 
ATOM   3314 C CA  . LEU C 3  126 ? 5.841   -14.801 25.538  1.00 29.45 ? 118  LEU I CA  1 
ATOM   3315 C C   . LEU C 3  126 ? 5.955   -14.081 26.881  1.00 29.07 ? 118  LEU I C   1 
ATOM   3316 O O   . LEU C 3  126 ? 5.000   -14.049 27.659  1.00 28.49 ? 118  LEU I O   1 
ATOM   3317 C CB  . LEU C 3  126 ? 6.402   -16.219 25.687  1.00 30.73 ? 118  LEU I CB  1 
ATOM   3318 C CG  . LEU C 3  126 ? 6.271   -17.160 24.488  1.00 32.23 ? 118  LEU I CG  1 
ATOM   3319 C CD1 . LEU C 3  126 ? 7.013   -18.456 24.777  1.00 32.40 ? 118  LEU I CD1 1 
ATOM   3320 C CD2 . LEU C 3  126 ? 4.801   -17.438 24.207  1.00 33.43 ? 118  LEU I CD2 1 
ATOM   3321 N N   . VAL C 3  127 ? 7.120   -13.507 27.150  1.00 28.03 ? 119  VAL I N   1 
ATOM   3322 C CA  . VAL C 3  127 ? 7.356   -12.820 28.418  1.00 29.40 ? 119  VAL I CA  1 
ATOM   3323 C C   . VAL C 3  127 ? 6.670   -11.466 28.575  1.00 29.76 ? 119  VAL I C   1 
ATOM   3324 O O   . VAL C 3  127 ? 6.611   -10.928 29.680  1.00 28.67 ? 119  VAL I O   1 
ATOM   3325 C CB  . VAL C 3  127 ? 8.870   -12.622 28.663  1.00 29.23 ? 119  VAL I CB  1 
ATOM   3326 C CG1 . VAL C 3  127 ? 9.562   -13.978 28.738  1.00 28.80 ? 119  VAL I CG1 1 
ATOM   3327 C CG2 . VAL C 3  127 ? 9.474   -11.777 27.545  1.00 29.70 ? 119  VAL I CG2 1 
ATOM   3328 N N   . VAL C 3  128 ? 6.147   -10.915 27.484  1.00 29.80 ? 120  VAL I N   1 
ATOM   3329 C CA  . VAL C 3  128 ? 5.492   -9.612  27.545  1.00 30.67 ? 120  VAL I CA  1 
ATOM   3330 C C   . VAL C 3  128 ? 4.055   -9.684  28.054  1.00 32.07 ? 120  VAL I C   1 
ATOM   3331 O O   . VAL C 3  128 ? 3.202   -10.340 27.455  1.00 31.52 ? 120  VAL I O   1 
ATOM   3332 C CB  . VAL C 3  128 ? 5.489   -8.925  26.163  1.00 31.17 ? 120  VAL I CB  1 
ATOM   3333 C CG1 . VAL C 3  128 ? 4.785   -7.579  26.255  1.00 31.06 ? 120  VAL I CG1 1 
ATOM   3334 C CG2 . VAL C 3  128 ? 6.916   -8.742  25.673  1.00 31.94 ? 120  VAL I CG2 1 
ATOM   3335 N N   . ASP C 3  129 ? 3.797   -8.996  29.161  1.00 33.59 ? 121  ASP I N   1 
ATOM   3336 C CA  . ASP C 3  129 ? 2.467   -8.969  29.764  1.00 35.49 ? 121  ASP I CA  1 
ATOM   3337 C C   . ASP C 3  129 ? 1.602   -7.943  29.038  1.00 35.01 ? 121  ASP I C   1 
ATOM   3338 O O   . ASP C 3  129 ? 1.922   -6.758  29.011  1.00 36.42 ? 121  ASP I O   1 
ATOM   3339 C CB  . ASP C 3  129 ? 2.584   -8.617  31.251  1.00 38.41 ? 121  ASP I CB  1 
ATOM   3340 C CG  . ASP C 3  129 ? 1.247   -8.631  31.964  1.00 41.21 ? 121  ASP I CG  1 
ATOM   3341 O OD1 . ASP C 3  129 ? 0.450   -7.693  31.757  1.00 43.08 ? 121  ASP I OD1 1 
ATOM   3342 O OD2 . ASP C 3  129 ? 0.995   -9.584  32.731  1.00 42.76 ? 121  ASP I OD2 1 
ATOM   3343 N N   . LEU C 3  130 ? 0.498   -8.405  28.460  1.00 34.32 ? 122  LEU I N   1 
ATOM   3344 C CA  . LEU C 3  130 ? -0.394  -7.534  27.698  1.00 34.11 ? 122  LEU I CA  1 
ATOM   3345 C C   . LEU C 3  130 ? -1.521  -6.900  28.510  1.00 32.32 ? 122  LEU I C   1 
ATOM   3346 O O   . LEU C 3  130 ? -2.101  -7.533  29.389  1.00 33.42 ? 122  LEU I O   1 
ATOM   3347 C CB  . LEU C 3  130 ? -0.989  -8.324  26.529  1.00 33.39 ? 122  LEU I CB  1 
ATOM   3348 C CG  . LEU C 3  130 ? 0.041   -9.018  25.631  1.00 34.41 ? 122  LEU I CG  1 
ATOM   3349 C CD1 . LEU C 3  130 ? -0.664  -9.956  24.662  1.00 34.03 ? 122  LEU I CD1 1 
ATOM   3350 C CD2 . LEU C 3  130 ? 0.858   -7.974  24.886  1.00 32.72 ? 122  LEU I CD2 1 
ATOM   3351 N N   . GLN C 3  131 ? -1.824  -5.641  28.204  1.00 31.63 ? 123  GLN I N   1 
ATOM   3352 C CA  . GLN C 3  131 ? -2.891  -4.912  28.883  1.00 30.93 ? 123  GLN I CA  1 
ATOM   3353 C C   . GLN C 3  131 ? -4.238  -5.240  28.249  1.00 30.88 ? 123  GLN I C   1 
ATOM   3354 O O   . GLN C 3  131 ? -4.395  -5.154  27.030  1.00 29.82 ? 123  GLN I O   1 
ATOM   3355 C CB  . GLN C 3  131 ? -2.644  -3.406  28.796  1.00 32.09 ? 123  GLN I CB  1 
ATOM   3356 C CG  . GLN C 3  131 ? -1.471  -2.915  29.623  1.00 35.18 ? 123  GLN I CG  1 
ATOM   3357 C CD  . GLN C 3  131 ? -1.740  -3.005  31.112  1.00 36.57 ? 123  GLN I CD  1 
ATOM   3358 O OE1 . GLN C 3  131 ? -2.654  -2.361  31.625  1.00 37.87 ? 123  GLN I OE1 1 
ATOM   3359 N NE2 . GLN C 3  131 ? -0.948  -3.808  31.812  1.00 37.58 ? 123  GLN I NE2 1 
ATOM   3360 N N   . ASP C 3  132 ? -5.204  -5.613  29.083  1.00 30.28 ? 124  ASP I N   1 
ATOM   3361 C CA  . ASP C 3  132 ? -6.551  -5.962  28.627  1.00 30.10 ? 124  ASP I CA  1 
ATOM   3362 C C   . ASP C 3  132 ? -7.179  -4.885  27.747  1.00 28.75 ? 124  ASP I C   1 
ATOM   3363 O O   . ASP C 3  132 ? -7.762  -5.185  26.704  1.00 27.63 ? 124  ASP I O   1 
ATOM   3364 C CB  . ASP C 3  132 ? -7.467  -6.195  29.831  1.00 31.97 ? 124  ASP I CB  1 
ATOM   3365 C CG  . ASP C 3  132 ? -7.101  -7.434  30.620  1.00 34.86 ? 124  ASP I CG  1 
ATOM   3366 O OD1 . ASP C 3  132 ? -7.487  -7.510  31.809  1.00 35.47 ? 124  ASP I OD1 1 
ATOM   3367 O OD2 . ASP C 3  132 ? -6.445  -8.334  30.054  1.00 35.47 ? 124  ASP I OD2 1 
ATOM   3368 N N   A THR C 3  133 ? -7.065  -3.634  28.182  0.25 28.39 ? 125  THR I N   1 
ATOM   3369 N N   B THR C 3  133 ? -7.063  -3.633  28.177  0.75 28.13 ? 125  THR I N   1 
ATOM   3370 C CA  A THR C 3  133 ? -7.626  -2.505  27.450  0.32 28.06 ? 125  THR I CA  1 
ATOM   3371 C CA  B THR C 3  133 ? -7.630  -2.514  27.435  0.68 27.86 ? 125  THR I CA  1 
ATOM   3372 C C   A THR C 3  133 ? -7.102  -2.421  26.019  0.18 28.08 ? 125  THR I C   1 
ATOM   3373 C C   B THR C 3  133 ? -7.110  -2.457  26.006  0.48 28.12 ? 125  THR I C   1 
ATOM   3374 O O   A THR C 3  133 ? -7.854  -2.113  25.094  0.15 28.10 ? 125  THR I O   1 
ATOM   3375 O O   B THR C 3  133 ? -7.869  -2.209  25.068  0.85 28.78 ? 125  THR I O   1 
ATOM   3376 C CB  A THR C 3  133 ? -7.330  -1.176  28.177  0.12 28.00 ? 125  THR I CB  1 
ATOM   3377 C CB  B THR C 3  133 ? -7.318  -1.173  28.126  0.81 27.65 ? 125  THR I CB  1 
ATOM   3378 O OG1 A THR C 3  133 ? -7.713  -0.074  27.344  0.37 27.91 ? 125  THR I OG1 1 
ATOM   3379 O OG1 B THR C 3  133 ? -5.912  -1.086  28.391  0.51 27.19 ? 125  THR I OG1 1 
ATOM   3380 C CG2 A THR C 3  133 ? -5.856  -1.074  28.518  0.28 27.77 ? 125  THR I CG2 1 
ATOM   3381 C CG2 B THR C 3  133 ? -8.091  -1.054  29.431  0.61 27.70 ? 125  THR I CG2 1 
ATOM   3382 N N   . PHE C 3  134 ? -5.813  -2.693  25.841  1.00 27.86 ? 126  PHE I N   1 
ATOM   3383 C CA  . PHE C 3  134 ? -5.206  -2.653  24.515  1.00 28.12 ? 126  PHE I CA  1 
ATOM   3384 C C   . PHE C 3  134 ? -5.661  -3.818  23.649  1.00 27.43 ? 126  PHE I C   1 
ATOM   3385 O O   . PHE C 3  134 ? -6.064  -3.630  22.499  1.00 28.01 ? 126  PHE I O   1 
ATOM   3386 C CB  . PHE C 3  134 ? -3.682  -2.670  24.618  1.00 27.74 ? 126  PHE I CB  1 
ATOM   3387 C CG  . PHE C 3  134 ? -2.993  -2.630  23.283  1.00 26.40 ? 126  PHE I CG  1 
ATOM   3388 C CD1 . PHE C 3  134 ? -3.027  -1.477  22.504  1.00 26.91 ? 126  PHE I CD1 1 
ATOM   3389 C CD2 . PHE C 3  134 ? -2.346  -3.756  22.787  1.00 25.84 ? 126  PHE I CD2 1 
ATOM   3390 C CE1 . PHE C 3  134 ? -2.429  -1.445  21.247  1.00 24.68 ? 126  PHE I CE1 1 
ATOM   3391 C CE2 . PHE C 3  134 ? -1.745  -3.735  21.529  1.00 27.33 ? 126  PHE I CE2 1 
ATOM   3392 C CZ  . PHE C 3  134 ? -1.787  -2.579  20.759  1.00 24.32 ? 126  PHE I CZ  1 
ATOM   3393 N N   . VAL C 3  135 ? -5.589  -5.026  24.197  1.00 26.94 ? 127  VAL I N   1 
ATOM   3394 C CA  . VAL C 3  135 ? -5.997  -6.211  23.454  1.00 26.97 ? 127  VAL I CA  1 
ATOM   3395 C C   . VAL C 3  135 ? -7.460  -6.085  23.031  1.00 27.57 ? 127  VAL I C   1 
ATOM   3396 O O   . VAL C 3  135 ? -7.826  -6.449  21.911  1.00 27.89 ? 127  VAL I O   1 
ATOM   3397 C CB  . VAL C 3  135 ? -5.813  -7.491  24.299  1.00 27.39 ? 127  VAL I CB  1 
ATOM   3398 C CG1 . VAL C 3  135 ? -6.313  -8.706  23.528  1.00 27.45 ? 127  VAL I CG1 1 
ATOM   3399 C CG2 . VAL C 3  135 ? -4.340  -7.672  24.652  1.00 27.93 ? 127  VAL I CG2 1 
ATOM   3400 N N   . SER C 3  136 ? -8.288  -5.557  23.927  1.00 27.56 ? 128  SER I N   1 
ATOM   3401 C CA  . SER C 3  136 ? -9.709  -5.383  23.650  1.00 28.27 ? 128  SER I CA  1 
ATOM   3402 C C   . SER C 3  136 ? -9.950  -4.375  22.533  1.00 27.85 ? 128  SER I C   1 
ATOM   3403 O O   . SER C 3  136 ? -10.709 -4.638  21.603  1.00 28.30 ? 128  SER I O   1 
ATOM   3404 C CB  . SER C 3  136 ? -10.442 -4.924  24.913  1.00 29.00 ? 128  SER I CB  1 
ATOM   3405 O OG  . SER C 3  136 ? -11.790 -4.597  24.619  1.00 32.31 ? 128  SER I OG  1 
ATOM   3406 N N   . ALA C 3  137 ? -9.311  -3.216  22.637  1.00 29.13 ? 129  ALA I N   1 
ATOM   3407 C CA  . ALA C 3  137 ? -9.465  -2.173  21.633  1.00 30.16 ? 129  ALA I CA  1 
ATOM   3408 C C   . ALA C 3  137 ? -9.048  -2.682  20.257  1.00 30.81 ? 129  ALA I C   1 
ATOM   3409 O O   . ALA C 3  137 ? -9.687  -2.367  19.255  1.00 31.41 ? 129  ALA I O   1 
ATOM   3410 C CB  . ALA C 3  137 ? -8.642  -0.950  22.018  1.00 29.28 ? 129  ALA I CB  1 
ATOM   3411 N N   A MET C 3  138 ? -7.979  -3.473  20.229  0.26 31.36 ? 130  MET I N   1 
ATOM   3412 N N   B MET C 3  138 ? -7.974  -3.465  20.205  0.67 31.55 ? 130  MET I N   1 
ATOM   3413 C CA  A MET C 3  138 ? -7.454  -4.047  18.995  0.22 31.89 ? 130  MET I CA  1 
ATOM   3414 C CA  B MET C 3  138 ? -7.494  -4.008  18.934  0.78 32.24 ? 130  MET I CA  1 
ATOM   3415 C C   A MET C 3  138 ? -8.476  -4.942  18.304  0.22 32.58 ? 130  MET I C   1 
ATOM   3416 C C   B MET C 3  138 ? -8.507  -4.939  18.284  0.47 32.85 ? 130  MET I C   1 
ATOM   3417 O O   A MET C 3  138 ? -8.702  -4.835  17.099  0.26 32.46 ? 130  MET I O   1 
ATOM   3418 O O   B MET C 3  138 ? -8.751  -4.865  17.079  0.74 32.48 ? 130  MET I O   1 
ATOM   3419 C CB  A MET C 3  138 ? -6.202  -4.874  19.300  0.10 31.50 ? 130  MET I CB  1 
ATOM   3420 C CB  B MET C 3  138 ? -6.186  -4.773  19.130  0.83 32.25 ? 130  MET I CB  1 
ATOM   3421 C CG  A MET C 3  138 ? -4.989  -4.061  19.702  0.28 30.80 ? 130  MET I CG  1 
ATOM   3422 C CG  B MET C 3  138 ? -4.951  -3.908  19.171  0.64 31.90 ? 130  MET I CG  1 
ATOM   3423 S SD  A MET C 3  138 ? -4.238  -3.246  18.290  0.45 30.47 ? 130  MET I SD  1 
ATOM   3424 S SD  B MET C 3  138 ? -3.477  -4.932  19.138  0.43 31.68 ? 130  MET I SD  1 
ATOM   3425 C CE  A MET C 3  138 ? -3.130  -4.528  17.726  0.16 30.32 ? 130  MET I CE  1 
ATOM   3426 C CE  B MET C 3  138 ? -3.650  -5.707  17.544  0.84 31.73 ? 130  MET I CE  1 
ATOM   3427 N N   . LYS C 3  139 ? -9.085  -5.828  19.083  1.00 33.10 ? 131  LYS I N   1 
ATOM   3428 C CA  . LYS C 3  139 ? -10.068 -6.768  18.569  1.00 34.43 ? 131  LYS I CA  1 
ATOM   3429 C C   . LYS C 3  139 ? -11.381 -6.080  18.219  1.00 34.75 ? 131  LYS I C   1 
ATOM   3430 O O   . LYS C 3  139 ? -11.993 -6.374  17.194  1.00 36.25 ? 131  LYS I O   1 
ATOM   3431 C CB  . LYS C 3  139 ? -10.320 -7.868  19.603  1.00 36.19 ? 131  LYS I CB  1 
ATOM   3432 C CG  . LYS C 3  139 ? -11.205 -9.006  19.120  1.00 38.43 ? 131  LYS I CG  1 
ATOM   3433 C CD  . LYS C 3  139 ? -10.552 -9.775  17.982  1.00 41.12 ? 131  LYS I CD  1 
ATOM   3434 C CE  . LYS C 3  139 ? -11.364 -11.009 17.618  1.00 42.05 ? 131  LYS I CE  1 
ATOM   3435 N NZ  . LYS C 3  139 ? -10.728 -11.792 16.522  1.00 43.87 ? 131  LYS I NZ  1 
ATOM   3436 N N   . THR C 3  140 ? -11.799 -5.149  19.070  1.00 34.07 ? 132  THR I N   1 
ATOM   3437 C CA  . THR C 3  140 ? -13.054 -4.432  18.876  1.00 34.27 ? 132  THR I CA  1 
ATOM   3438 C C   . THR C 3  140 ? -13.025 -3.374  17.773  1.00 33.89 ? 132  THR I C   1 
ATOM   3439 O O   . THR C 3  140 ? -13.885 -3.364  16.892  1.00 33.48 ? 132  THR I O   1 
ATOM   3440 C CB  . THR C 3  140 ? -13.494 -3.755  20.191  1.00 34.03 ? 132  THR I CB  1 
ATOM   3441 O OG1 . THR C 3  140 ? -13.578 -4.742  21.227  1.00 34.89 ? 132  THR I OG1 1 
ATOM   3442 C CG2 . THR C 3  140 ? -14.854 -3.089  20.026  1.00 34.67 ? 132  THR I CG2 1 
ATOM   3443 N N   . LEU C 3  141 ? -12.035 -2.488  17.822  1.00 33.45 ? 133  LEU I N   1 
ATOM   3444 C CA  . LEU C 3  141 ? -11.923 -1.414  16.842  1.00 33.51 ? 133  LEU I CA  1 
ATOM   3445 C C   . LEU C 3  141 ? -11.280 -1.797  15.514  1.00 33.25 ? 133  LEU I C   1 
ATOM   3446 O O   . LEU C 3  141 ? -11.717 -1.336  14.455  1.00 33.49 ? 133  LEU I O   1 
ATOM   3447 C CB  . LEU C 3  141 ? -11.150 -0.239  17.444  1.00 34.52 ? 133  LEU I CB  1 
ATOM   3448 C CG  . LEU C 3  141 ? -11.781 0.489   18.633  1.00 36.38 ? 133  LEU I CG  1 
ATOM   3449 C CD1 . LEU C 3  141 ? -10.806 1.525   19.171  1.00 35.81 ? 133  LEU I CD1 1 
ATOM   3450 C CD2 . LEU C 3  141 ? -13.081 1.149   18.202  1.00 36.75 ? 133  LEU I CD2 1 
ATOM   3451 N N   . TYR C 3  142 ? -10.247 -2.632  15.560  1.00 31.13 ? 134  TYR I N   1 
ATOM   3452 C CA  . TYR C 3  142 ? -9.553  -3.018  14.340  1.00 30.26 ? 134  TYR I CA  1 
ATOM   3453 C C   . TYR C 3  142 ? -9.620  -4.490  13.972  1.00 30.17 ? 134  TYR I C   1 
ATOM   3454 O O   . TYR C 3  142 ? -8.896  -4.939  13.086  1.00 30.64 ? 134  TYR I O   1 
ATOM   3455 C CB  . TYR C 3  142 ? -8.091  -2.573  14.416  1.00 26.92 ? 134  TYR I CB  1 
ATOM   3456 C CG  . TYR C 3  142 ? -7.936  -1.072  14.482  1.00 27.12 ? 134  TYR I CG  1 
ATOM   3457 C CD1 . TYR C 3  142 ? -8.101  -0.383  15.682  1.00 24.45 ? 134  TYR I CD1 1 
ATOM   3458 C CD2 . TYR C 3  142 ? -7.682  -0.332  13.327  1.00 25.05 ? 134  TYR I CD2 1 
ATOM   3459 C CE1 . TYR C 3  142 ? -8.022  1.007   15.732  1.00 26.36 ? 134  TYR I CE1 1 
ATOM   3460 C CE2 . TYR C 3  142 ? -7.603  1.056   13.365  1.00 27.64 ? 134  TYR I CE2 1 
ATOM   3461 C CZ  . TYR C 3  142 ? -7.775  1.719   14.566  1.00 25.86 ? 134  TYR I CZ  1 
ATOM   3462 O OH  . TYR C 3  142 ? -7.713  3.091   14.591  1.00 27.72 ? 134  TYR I OH  1 
ATOM   3463 N N   . LEU C 3  143 ? -10.485 -5.241  14.646  1.00 30.88 ? 135  LEU I N   1 
ATOM   3464 C CA  . LEU C 3  143 ? -10.637 -6.663  14.356  1.00 32.39 ? 135  LEU I CA  1 
ATOM   3465 C C   . LEU C 3  143 ? -9.279  -7.357  14.263  1.00 33.05 ? 135  LEU I C   1 
ATOM   3466 O O   . LEU C 3  143 ? -9.094  -8.277  13.465  1.00 33.24 ? 135  LEU I O   1 
ATOM   3467 C CB  . LEU C 3  143 ? -11.404 -6.841  13.038  1.00 34.32 ? 135  LEU I CB  1 
ATOM   3468 C CG  . LEU C 3  143 ? -12.900 -6.496  13.001  1.00 36.28 ? 135  LEU I CG  1 
ATOM   3469 C CD1 . LEU C 3  143 ? -13.160 -5.132  13.624  1.00 37.76 ? 135  LEU I CD1 1 
ATOM   3470 C CD2 . LEU C 3  143 ? -13.377 -6.518  11.554  1.00 37.50 ? 135  LEU I CD2 1 
ATOM   3471 N N   . ALA C 3  144 ? -8.333  -6.915  15.088  1.00 32.79 ? 136  ALA I N   1 
ATOM   3472 C CA  . ALA C 3  144 ? -6.988  -7.483  15.090  1.00 33.25 ? 136  ALA I CA  1 
ATOM   3473 C C   . ALA C 3  144 ? -6.691  -8.253  16.372  1.00 33.96 ? 136  ALA I C   1 
ATOM   3474 O O   . ALA C 3  144 ? -6.964  -7.774  17.471  1.00 34.42 ? 136  ALA I O   1 
ATOM   3475 C CB  . ALA C 3  144 ? -5.960  -6.374  14.904  1.00 32.64 ? 136  ALA I CB  1 
ATOM   3476 N N   . ASP C 3  145 ? -6.122  -9.444  16.224  1.00 34.38 ? 137  ASP I N   1 
ATOM   3477 C CA  . ASP C 3  145 ? -5.779  -10.272 17.373  1.00 35.30 ? 137  ASP I CA  1 
ATOM   3478 C C   . ASP C 3  145 ? -4.311  -10.125 17.755  1.00 34.65 ? 137  ASP I C   1 
ATOM   3479 O O   . ASP C 3  145 ? -3.483  -9.719  16.940  1.00 34.07 ? 137  ASP I O   1 
ATOM   3480 C CB  . ASP C 3  145 ? -6.075  -11.746 17.079  1.00 37.81 ? 137  ASP I CB  1 
ATOM   3481 C CG  . ASP C 3  145 ? -7.559  -12.056 17.072  1.00 40.38 ? 137  ASP I CG  1 
ATOM   3482 O OD1 . ASP C 3  145 ? -8.231  -11.783 18.091  1.00 42.73 ? 137  ASP I OD1 1 
ATOM   3483 O OD2 . ASP C 3  145 ? -8.054  -12.580 16.053  1.00 43.10 ? 137  ASP I OD2 1 
ATOM   3484 N N   . THR C 3  146 ? -4.003  -10.454 19.006  1.00 33.39 ? 138  THR I N   1 
ATOM   3485 C CA  . THR C 3  146 ? -2.641  -10.389 19.520  1.00 34.22 ? 138  THR I CA  1 
ATOM   3486 C C   . THR C 3  146 ? -2.240  -11.818 19.870  1.00 33.89 ? 138  THR I C   1 
ATOM   3487 O O   . THR C 3  146 ? -2.985  -12.527 20.548  1.00 34.28 ? 138  THR I O   1 
ATOM   3488 C CB  . THR C 3  146 ? -2.561  -9.508  20.778  1.00 35.12 ? 138  THR I CB  1 
ATOM   3489 O OG1 . THR C 3  146 ? -3.070  -8.202  20.479  1.00 35.63 ? 138  THR I OG1 1 
ATOM   3490 C CG2 . THR C 3  146 ? -1.121  -9.380  21.248  1.00 35.71 ? 138  THR I CG2 1 
ATOM   3491 N N   . PHE C 3  147 ? -1.066  -12.240 19.413  1.00 33.37 ? 139  PHE I N   1 
ATOM   3492 C CA  . PHE C 3  147 ? -0.612  -13.604 19.656  1.00 34.27 ? 139  PHE I CA  1 
ATOM   3493 C C   . PHE C 3  147 ? 0.723   -13.739 20.376  1.00 34.50 ? 139  PHE I C   1 
ATOM   3494 O O   . PHE C 3  147 ? 1.756   -13.299 19.872  1.00 34.23 ? 139  PHE I O   1 
ATOM   3495 C CB  . PHE C 3  147 ? -0.511  -14.358 18.329  1.00 35.27 ? 139  PHE I CB  1 
ATOM   3496 C CG  . PHE C 3  147 ? -1.807  -14.456 17.584  1.00 37.00 ? 139  PHE I CG  1 
ATOM   3497 C CD1 . PHE C 3  147 ? -2.799  -15.338 17.999  1.00 37.73 ? 139  PHE I CD1 1 
ATOM   3498 C CD2 . PHE C 3  147 ? -2.041  -13.659 16.468  1.00 36.88 ? 139  PHE I CD2 1 
ATOM   3499 C CE1 . PHE C 3  147 ? -4.007  -15.428 17.313  1.00 37.63 ? 139  PHE I CE1 1 
ATOM   3500 C CE2 . PHE C 3  147 ? -3.244  -13.739 15.774  1.00 37.68 ? 139  PHE I CE2 1 
ATOM   3501 C CZ  . PHE C 3  147 ? -4.230  -14.626 16.198  1.00 37.88 ? 139  PHE I CZ  1 
ATOM   3502 N N   . PRO C 3  148 ? 0.718   -14.345 21.574  1.00 34.91 ? 140  PRO I N   1 
ATOM   3503 C CA  . PRO C 3  148 ? 1.973   -14.519 22.306  1.00 34.54 ? 140  PRO I CA  1 
ATOM   3504 C C   . PRO C 3  148 ? 2.859   -15.417 21.447  1.00 34.76 ? 140  PRO I C   1 
ATOM   3505 O O   . PRO C 3  148 ? 2.393   -16.421 20.906  1.00 35.79 ? 140  PRO I O   1 
ATOM   3506 C CB  . PRO C 3  148 ? 1.523   -15.193 23.596  1.00 35.47 ? 140  PRO I CB  1 
ATOM   3507 C CG  . PRO C 3  148 ? 0.175   -14.578 23.822  1.00 35.29 ? 140  PRO I CG  1 
ATOM   3508 C CD  . PRO C 3  148 ? -0.436  -14.654 22.436  1.00 34.97 ? 140  PRO I CD  1 
ATOM   3509 N N   . THR C 3  149 ? 4.130   -15.059 21.318  1.00 33.66 ? 141  THR I N   1 
ATOM   3510 C CA  . THR C 3  149 ? 5.038   -15.826 20.481  1.00 34.65 ? 141  THR I CA  1 
ATOM   3511 C C   . THR C 3  149 ? 6.418   -15.986 21.106  1.00 35.14 ? 141  THR I C   1 
ATOM   3512 O O   . THR C 3  149 ? 6.915   -15.080 21.776  1.00 34.58 ? 141  THR I O   1 
ATOM   3513 C CB  . THR C 3  149 ? 5.205   -15.134 19.110  1.00 34.41 ? 141  THR I CB  1 
ATOM   3514 O OG1 . THR C 3  149 ? 3.913   -14.859 18.554  1.00 34.70 ? 141  THR I OG1 1 
ATOM   3515 C CG2 . THR C 3  149 ? 5.988   -16.013 18.156  1.00 34.76 ? 141  THR I CG2 1 
ATOM   3516 N N   . ASN C 3  150 ? 7.034   -17.142 20.883  1.00 35.47 ? 142  ASN I N   1 
ATOM   3517 C CA  . ASN C 3  150 ? 8.367   -17.389 21.412  1.00 35.83 ? 142  ASN I CA  1 
ATOM   3518 C C   . ASN C 3  150 ? 9.409   -16.925 20.402  1.00 35.09 ? 142  ASN I C   1 
ATOM   3519 O O   . ASN C 3  150 ? 9.893   -17.710 19.588  1.00 33.99 ? 142  ASN I O   1 
ATOM   3520 C CB  . ASN C 3  150 ? 8.568   -18.874 21.711  1.00 37.91 ? 142  ASN I CB  1 
ATOM   3521 C CG  . ASN C 3  150 ? 9.991   -19.188 22.114  1.00 39.44 ? 142  ASN I CG  1 
ATOM   3522 O OD1 . ASN C 3  150 ? 10.595  -18.461 22.901  1.00 39.94 ? 142  ASN I OD1 1 
ATOM   3523 N ND2 . ASN C 3  150 ? 10.536  -20.275 21.579  1.00 41.38 ? 142  ASN I ND2 1 
ATOM   3524 N N   . PHE C 3  151 ? 9.753   -15.643 20.466  1.00 34.59 ? 143  PHE I N   1 
ATOM   3525 C CA  . PHE C 3  151 ? 10.723  -15.066 19.546  1.00 35.27 ? 143  PHE I CA  1 
ATOM   3526 C C   . PHE C 3  151 ? 12.158  -15.547 19.746  1.00 36.51 ? 143  PHE I C   1 
ATOM   3527 O O   . PHE C 3  151 ? 13.029  -15.266 18.921  1.00 36.65 ? 143  PHE I O   1 
ATOM   3528 C CB  . PHE C 3  151 ? 10.663  -13.537 19.615  1.00 34.42 ? 143  PHE I CB  1 
ATOM   3529 C CG  . PHE C 3  151 ? 9.454   -12.950 18.938  1.00 33.86 ? 143  PHE I CG  1 
ATOM   3530 C CD1 . PHE C 3  151 ? 9.208   -13.202 17.590  1.00 34.32 ? 143  PHE I CD1 1 
ATOM   3531 C CD2 . PHE C 3  151 ? 8.563   -12.147 19.641  1.00 33.28 ? 143  PHE I CD2 1 
ATOM   3532 C CE1 . PHE C 3  151 ? 8.092   -12.664 16.953  1.00 33.22 ? 143  PHE I CE1 1 
ATOM   3533 C CE2 . PHE C 3  151 ? 7.441   -11.603 19.013  1.00 34.00 ? 143  PHE I CE2 1 
ATOM   3534 C CZ  . PHE C 3  151 ? 7.207   -11.863 17.666  1.00 33.17 ? 143  PHE I CZ  1 
ATOM   3535 N N   . ARG C 3  152 ? 12.408  -16.270 20.834  1.00 37.38 ? 144  ARG I N   1 
ATOM   3536 C CA  . ARG C 3  152 ? 13.747  -16.791 21.080  1.00 38.45 ? 144  ARG I CA  1 
ATOM   3537 C C   . ARG C 3  152 ? 13.958  -18.025 20.204  1.00 40.25 ? 144  ARG I C   1 
ATOM   3538 O O   . ARG C 3  152 ? 14.998  -18.683 20.255  1.00 40.53 ? 144  ARG I O   1 
ATOM   3539 C CB  . ARG C 3  152 ? 13.936  -17.117 22.566  1.00 37.66 ? 144  ARG I CB  1 
ATOM   3540 C CG  . ARG C 3  152 ? 13.965  -15.868 23.453  1.00 36.39 ? 144  ARG I CG  1 
ATOM   3541 C CD  . ARG C 3  152 ? 15.011  -14.873 22.948  1.00 36.80 ? 144  ARG I CD  1 
ATOM   3542 N NE  . ARG C 3  152 ? 14.869  -13.532 23.518  1.00 35.62 ? 144  ARG I NE  1 
ATOM   3543 C CZ  . ARG C 3  152 ? 15.425  -13.127 24.656  1.00 36.00 ? 144  ARG I CZ  1 
ATOM   3544 N NH1 . ARG C 3  152 ? 15.229  -11.885 25.083  1.00 36.03 ? 144  ARG I NH1 1 
ATOM   3545 N NH2 . ARG C 3  152 ? 16.182  -13.953 25.365  1.00 33.51 ? 144  ARG I NH2 1 
ATOM   3546 N N   . ASP C 3  153 ? 12.943  -18.319 19.397  1.00 41.54 ? 145  ASP I N   1 
ATOM   3547 C CA  . ASP C 3  153 ? 12.964  -19.425 18.448  1.00 42.98 ? 145  ASP I CA  1 
ATOM   3548 C C   . ASP C 3  153 ? 12.504  -18.831 17.119  1.00 42.94 ? 145  ASP I C   1 
ATOM   3549 O O   . ASP C 3  153 ? 11.378  -19.056 16.674  1.00 42.71 ? 145  ASP I O   1 
ATOM   3550 C CB  . ASP C 3  153 ? 12.013  -20.543 18.890  1.00 44.30 ? 145  ASP I CB  1 
ATOM   3551 C CG  . ASP C 3  153 ? 11.860  -21.634 17.837  1.00 46.57 ? 145  ASP I CG  1 
ATOM   3552 O OD1 . ASP C 3  153 ? 12.874  -22.014 17.215  1.00 47.58 ? 145  ASP I OD1 1 
ATOM   3553 O OD2 . ASP C 3  153 ? 10.725  -22.119 17.640  1.00 47.02 ? 145  ASP I OD2 1 
ATOM   3554 N N   . SER C 3  154 ? 13.389  -18.051 16.507  1.00 43.99 ? 146  SER I N   1 
ATOM   3555 C CA  . SER C 3  154 ? 13.117  -17.383 15.239  1.00 45.12 ? 146  SER I CA  1 
ATOM   3556 C C   . SER C 3  154 ? 12.368  -18.247 14.231  1.00 45.23 ? 146  SER I C   1 
ATOM   3557 O O   . SER C 3  154 ? 11.188  -18.019 13.965  1.00 45.30 ? 146  SER I O   1 
ATOM   3558 C CB  . SER C 3  154 ? 14.429  -16.901 14.617  1.00 45.85 ? 146  SER I CB  1 
ATOM   3559 O OG  . SER C 3  154 ? 15.109  -16.018 15.490  1.00 47.97 ? 146  SER I OG  1 
ATOM   3560 N N   . ALA C 3  155 ? 13.061  -19.234 13.671  1.00 45.11 ? 147  ALA I N   1 
ATOM   3561 C CA  . ALA C 3  155 ? 12.470  -20.128 12.679  1.00 44.97 ? 147  ALA I CA  1 
ATOM   3562 C C   . ALA C 3  155 ? 11.038  -20.513 13.031  1.00 44.37 ? 147  ALA I C   1 
ATOM   3563 O O   . ALA C 3  155 ? 10.142  -20.439 12.189  1.00 44.18 ? 147  ALA I O   1 
ATOM   3564 C CB  . ALA C 3  155 ? 13.327  -21.381 12.532  1.00 45.38 ? 147  ALA I CB  1 
ATOM   3565 N N   . GLY C 3  156 ? 10.828  -20.921 14.277  1.00 43.62 ? 148  GLY I N   1 
ATOM   3566 C CA  . GLY C 3  156 ? 9.500   -21.312 14.716  1.00 43.51 ? 148  GLY I CA  1 
ATOM   3567 C C   . GLY C 3  156 ? 8.498   -20.172 14.691  1.00 43.30 ? 148  GLY I C   1 
ATOM   3568 O O   . GLY C 3  156 ? 7.372   -20.338 14.221  1.00 43.61 ? 148  GLY I O   1 
ATOM   3569 N N   . ALA C 3  157 ? 8.904   -19.013 15.198  1.00 42.25 ? 149  ALA I N   1 
ATOM   3570 C CA  . ALA C 3  157 ? 8.029   -17.848 15.233  1.00 41.60 ? 149  ALA I CA  1 
ATOM   3571 C C   . ALA C 3  157 ? 7.727   -17.366 13.820  1.00 41.39 ? 149  ALA I C   1 
ATOM   3572 O O   . ALA C 3  157 ? 6.601   -16.974 13.513  1.00 40.77 ? 149  ALA I O   1 
ATOM   3573 C CB  . ALA C 3  157 ? 8.679   -16.728 16.039  1.00 41.56 ? 149  ALA I CB  1 
ATOM   3574 N N   . MET C 3  158 ? 8.740   -17.396 12.962  1.00 41.51 ? 150  MET I N   1 
ATOM   3575 C CA  . MET C 3  158 ? 8.575   -16.955 11.586  1.00 42.40 ? 150  MET I CA  1 
ATOM   3576 C C   . MET C 3  158 ? 7.540   -17.812 10.865  1.00 42.03 ? 150  MET I C   1 
ATOM   3577 O O   . MET C 3  158 ? 6.703   -17.294 10.126  1.00 41.45 ? 150  MET I O   1 
ATOM   3578 C CB  . MET C 3  158 ? 9.913   -17.017 10.848  1.00 43.64 ? 150  MET I CB  1 
ATOM   3579 C CG  . MET C 3  158 ? 9.892   -16.339 9.490   1.00 46.31 ? 150  MET I CG  1 
ATOM   3580 S SD  . MET C 3  158 ? 11.501  -16.343 8.684   1.00 50.01 ? 150  MET I SD  1 
ATOM   3581 C CE  . MET C 3  158 ? 11.426  -17.912 7.811   1.00 49.10 ? 150  MET I CE  1 
ATOM   3582 N N   . LYS C 3  159 ? 7.592   -19.123 11.082  1.00 42.21 ? 151  LYS I N   1 
ATOM   3583 C CA  . LYS C 3  159 ? 6.639   -20.022 10.445  1.00 42.50 ? 151  LYS I CA  1 
ATOM   3584 C C   . LYS C 3  159 ? 5.249   -19.804 11.024  1.00 42.35 ? 151  LYS I C   1 
ATOM   3585 O O   . LYS C 3  159 ? 4.246   -19.894 10.316  1.00 42.60 ? 151  LYS I O   1 
ATOM   3586 C CB  . LYS C 3  159 ? 7.056   -21.481 10.639  1.00 44.48 ? 151  LYS I CB  1 
ATOM   3587 C CG  . LYS C 3  159 ? 6.087   -22.466 10.002  1.00 46.12 ? 151  LYS I CG  1 
ATOM   3588 C CD  . LYS C 3  159 ? 6.627   -23.883 9.992   1.00 48.39 ? 151  LYS I CD  1 
ATOM   3589 C CE  . LYS C 3  159 ? 5.675   -24.808 9.244   1.00 49.38 ? 151  LYS I CE  1 
ATOM   3590 N NZ  . LYS C 3  159 ? 6.223   -26.182 9.080   1.00 51.11 ? 151  LYS I NZ  1 
ATOM   3591 N N   . GLN C 3  160 ? 5.195   -19.517 12.319  1.00 41.36 ? 152  GLN I N   1 
ATOM   3592 C CA  . GLN C 3  160 ? 3.928   -19.276 12.996  1.00 41.32 ? 152  GLN I CA  1 
ATOM   3593 C C   . GLN C 3  160 ? 3.247   -18.059 12.376  1.00 41.05 ? 152  GLN I C   1 
ATOM   3594 O O   . GLN C 3  160 ? 2.047   -18.075 12.091  1.00 40.73 ? 152  GLN I O   1 
ATOM   3595 C CB  . GLN C 3  160 ? 4.178   -19.025 14.483  1.00 42.75 ? 152  GLN I CB  1 
ATOM   3596 C CG  . GLN C 3  160 ? 2.928   -18.767 15.306  1.00 44.96 ? 152  GLN I CG  1 
ATOM   3597 C CD  . GLN C 3  160 ? 3.257   -18.400 16.740  1.00 46.96 ? 152  GLN I CD  1 
ATOM   3598 O OE1 . GLN C 3  160 ? 3.980   -19.123 17.426  1.00 47.74 ? 152  GLN I OE1 1 
ATOM   3599 N NE2 . GLN C 3  160 ? 2.726   -17.271 17.202  1.00 46.89 ? 152  GLN I NE2 1 
ATOM   3600 N N   . ILE C 3  161 ? 4.029   -17.006 12.165  1.00 39.82 ? 153  ILE I N   1 
ATOM   3601 C CA  . ILE C 3  161 ? 3.519   -15.771 11.585  1.00 38.65 ? 153  ILE I CA  1 
ATOM   3602 C C   . ILE C 3  161 ? 3.130   -15.948 10.120  1.00 38.72 ? 153  ILE I C   1 
ATOM   3603 O O   . ILE C 3  161 ? 2.014   -15.608 9.728   1.00 38.12 ? 153  ILE I O   1 
ATOM   3604 C CB  . ILE C 3  161 ? 4.562   -14.638 11.704  1.00 37.61 ? 153  ILE I CB  1 
ATOM   3605 C CG1 . ILE C 3  161 ? 4.815   -14.330 13.183  1.00 36.92 ? 153  ILE I CG1 1 
ATOM   3606 C CG2 . ILE C 3  161 ? 4.074   -13.394 10.972  1.00 36.91 ? 153  ILE I CG2 1 
ATOM   3607 C CD1 . ILE C 3  161 ? 5.887   -13.285 13.428  1.00 36.16 ? 153  ILE I CD1 1 
ATOM   3608 N N   . ASN C 3  162 ? 4.043   -16.484 9.316   1.00 39.21 ? 154  ASN I N   1 
ATOM   3609 C CA  . ASN C 3  162 ? 3.762   -16.689 7.899   1.00 40.79 ? 154  ASN I CA  1 
ATOM   3610 C C   . ASN C 3  162 ? 2.553   -17.594 7.695   1.00 41.67 ? 154  ASN I C   1 
ATOM   3611 O O   . ASN C 3  162 ? 1.707   -17.329 6.840   1.00 41.40 ? 154  ASN I O   1 
ATOM   3612 C CB  . ASN C 3  162 ? 4.978   -17.284 7.185   1.00 40.81 ? 154  ASN I CB  1 
ATOM   3613 C CG  . ASN C 3  162 ? 6.173   -16.353 7.198   1.00 41.94 ? 154  ASN I CG  1 
ATOM   3614 O OD1 . ASN C 3  162 ? 6.022   -15.130 7.157   1.00 41.76 ? 154  ASN I OD1 1 
ATOM   3615 N ND2 . ASN C 3  162 ? 7.371   -16.926 7.237   1.00 42.48 ? 154  ASN I ND2 1 
ATOM   3616 N N   . ASP C 3  163 ? 2.474   -18.662 8.480   1.00 42.23 ? 155  ASP I N   1 
ATOM   3617 C CA  . ASP C 3  163 ? 1.356   -19.590 8.379   1.00 43.51 ? 155  ASP I CA  1 
ATOM   3618 C C   . ASP C 3  163 ? 0.040   -18.882 8.673   1.00 43.31 ? 155  ASP I C   1 
ATOM   3619 O O   . ASP C 3  163 ? -0.961  -19.106 7.992   1.00 44.24 ? 155  ASP I O   1 
ATOM   3620 C CB  . ASP C 3  163 ? 1.550   -20.758 9.350   1.00 45.22 ? 155  ASP I CB  1 
ATOM   3621 C CG  . ASP C 3  163 ? 2.513   -21.804 8.818   1.00 47.07 ? 155  ASP I CG  1 
ATOM   3622 O OD1 . ASP C 3  163 ? 3.594   -21.428 8.316   1.00 48.62 ? 155  ASP I OD1 1 
ATOM   3623 O OD2 . ASP C 3  163 ? 2.191   -23.008 8.908   1.00 48.30 ? 155  ASP I OD2 1 
ATOM   3624 N N   . TYR C 3  164 ? 0.046   -18.021 9.685   1.00 41.87 ? 156  TYR I N   1 
ATOM   3625 C CA  . TYR C 3  164 ? -1.153  -17.284 10.057  1.00 40.97 ? 156  TYR I CA  1 
ATOM   3626 C C   . TYR C 3  164 ? -1.589  -16.347 8.936   1.00 41.24 ? 156  TYR I C   1 
ATOM   3627 O O   . TYR C 3  164 ? -2.766  -16.299 8.580   1.00 40.68 ? 156  TYR I O   1 
ATOM   3628 C CB  . TYR C 3  164 ? -0.902  -16.469 11.326  1.00 39.88 ? 156  TYR I CB  1 
ATOM   3629 C CG  . TYR C 3  164 ? -2.051  -15.561 11.698  1.00 38.25 ? 156  TYR I CG  1 
ATOM   3630 C CD1 . TYR C 3  164 ? -3.238  -16.079 12.215  1.00 37.44 ? 156  TYR I CD1 1 
ATOM   3631 C CD2 . TYR C 3  164 ? -1.956  -14.182 11.519  1.00 37.75 ? 156  TYR I CD2 1 
ATOM   3632 C CE1 . TYR C 3  164 ? -4.303  -15.242 12.547  1.00 37.97 ? 156  TYR I CE1 1 
ATOM   3633 C CE2 . TYR C 3  164 ? -3.013  -13.338 11.846  1.00 37.37 ? 156  TYR I CE2 1 
ATOM   3634 C CZ  . TYR C 3  164 ? -4.182  -13.872 12.360  1.00 37.13 ? 156  TYR I CZ  1 
ATOM   3635 O OH  . TYR C 3  164 ? -5.220  -13.033 12.692  1.00 37.86 ? 156  TYR I OH  1 
ATOM   3636 N N   . VAL C 3  165 ? -0.636  -15.598 8.389   1.00 41.80 ? 157  VAL I N   1 
ATOM   3637 C CA  . VAL C 3  165 ? -0.928  -14.659 7.311   1.00 42.88 ? 157  VAL I CA  1 
ATOM   3638 C C   . VAL C 3  165 ? -1.460  -15.395 6.086   1.00 44.07 ? 157  VAL I C   1 
ATOM   3639 O O   . VAL C 3  165 ? -2.462  -14.989 5.498   1.00 44.27 ? 157  VAL I O   1 
ATOM   3640 C CB  . VAL C 3  165 ? 0.332   -13.854 6.913   1.00 42.59 ? 157  VAL I CB  1 
ATOM   3641 C CG1 . VAL C 3  165 ? 0.019   -12.932 5.739   1.00 41.80 ? 157  VAL I CG1 1 
ATOM   3642 C CG2 . VAL C 3  165 ? 0.818   -13.038 8.100   1.00 42.08 ? 157  VAL I CG2 1 
ATOM   3643 N N   . ALA C 3  166 ? -0.790  -16.478 5.708   1.00 45.34 ? 158  ALA I N   1 
ATOM   3644 C CA  . ALA C 3  166 ? -1.210  -17.265 4.556   1.00 47.19 ? 158  ALA I CA  1 
ATOM   3645 C C   . ALA C 3  166 ? -2.656  -17.711 4.741   1.00 48.49 ? 158  ALA I C   1 
ATOM   3646 O O   . ALA C 3  166 ? -3.462  -17.640 3.815   1.00 48.83 ? 158  ALA I O   1 
ATOM   3647 C CB  . ALA C 3  166 ? -0.304  -18.477 4.388   1.00 46.56 ? 158  ALA I CB  1 
ATOM   3648 N N   . LYS C 3  167 ? -2.977  -18.166 5.947   1.00 49.74 ? 159  LYS I N   1 
ATOM   3649 C CA  . LYS C 3  167 ? -4.327  -18.616 6.265   1.00 51.14 ? 159  LYS I CA  1 
ATOM   3650 C C   . LYS C 3  167 ? -5.332  -17.479 6.107   1.00 51.49 ? 159  LYS I C   1 
ATOM   3651 O O   . LYS C 3  167 ? -6.369  -17.636 5.463   1.00 51.68 ? 159  LYS I O   1 
ATOM   3652 C CB  . LYS C 3  167 ? -4.379  -19.140 7.703   1.00 52.28 ? 159  LYS I CB  1 
ATOM   3653 C CG  . LYS C 3  167 ? -5.784  -19.413 8.217   1.00 53.67 ? 159  LYS I CG  1 
ATOM   3654 C CD  . LYS C 3  167 ? -5.792  -19.581 9.728   1.00 54.92 ? 159  LYS I CD  1 
ATOM   3655 C CE  . LYS C 3  167 ? -7.210  -19.674 10.268  1.00 55.65 ? 159  LYS I CE  1 
ATOM   3656 N NZ  . LYS C 3  167 ? -7.235  -19.721 11.758  1.00 56.55 ? 159  LYS I NZ  1 
ATOM   3657 N N   . GLN C 3  168 ? -5.010  -16.334 6.701   1.00 51.64 ? 160  GLN I N   1 
ATOM   3658 C CA  . GLN C 3  168 ? -5.873  -15.159 6.659   1.00 51.77 ? 160  GLN I CA  1 
ATOM   3659 C C   . GLN C 3  168 ? -6.061  -14.580 5.260   1.00 51.85 ? 160  GLN I C   1 
ATOM   3660 O O   . GLN C 3  168 ? -7.106  -14.000 4.959   1.00 52.28 ? 160  GLN I O   1 
ATOM   3661 C CB  . GLN C 3  168 ? -5.317  -14.075 7.585   1.00 51.60 ? 160  GLN I CB  1 
ATOM   3662 C CG  . GLN C 3  168 ? -5.253  -14.486 9.046   1.00 51.53 ? 160  GLN I CG  1 
ATOM   3663 C CD  . GLN C 3  168 ? -6.624  -14.747 9.636   1.00 51.21 ? 160  GLN I CD  1 
ATOM   3664 O OE1 . GLN C 3  168 ? -7.453  -13.841 9.735   1.00 50.46 ? 160  GLN I OE1 1 
ATOM   3665 N NE2 . GLN C 3  168 ? -6.872  -15.991 10.031  1.00 51.56 ? 160  GLN I NE2 1 
ATOM   3666 N N   . THR C 3  169 ? -5.052  -14.728 4.409   1.00 51.92 ? 161  THR I N   1 
ATOM   3667 C CA  . THR C 3  169 ? -5.128  -14.201 3.051   1.00 51.84 ? 161  THR I CA  1 
ATOM   3668 C C   . THR C 3  169 ? -5.520  -15.274 2.042   1.00 52.13 ? 161  THR I C   1 
ATOM   3669 O O   . THR C 3  169 ? -5.366  -15.089 0.835   1.00 52.18 ? 161  THR I O   1 
ATOM   3670 C CB  . THR C 3  169 ? -3.785  -13.581 2.618   1.00 51.55 ? 161  THR I CB  1 
ATOM   3671 O OG1 . THR C 3  169 ? -2.764  -14.584 2.636   1.00 51.38 ? 161  THR I OG1 1 
ATOM   3672 C CG2 . THR C 3  169 ? -3.397  -12.451 3.556   1.00 51.70 ? 161  THR I CG2 1 
ATOM   3673 N N   . LYS C 3  170 ? -6.027  -16.395 2.546   1.00 52.28 ? 162  LYS I N   1 
ATOM   3674 C CA  . LYS C 3  170 ? -6.451  -17.502 1.696   1.00 52.21 ? 162  LYS I CA  1 
ATOM   3675 C C   . LYS C 3  170 ? -5.323  -18.000 0.796   1.00 51.85 ? 162  LYS I C   1 
ATOM   3676 O O   . LYS C 3  170 ? -5.572  -18.617 -0.239  1.00 52.29 ? 162  LYS I O   1 
ATOM   3677 C CB  . LYS C 3  170 ? -7.644  -17.075 0.836   1.00 52.25 ? 162  LYS I CB  1 
ATOM   3678 N N   . GLY C 3  171 ? -4.085  -17.728 1.195   1.00 51.19 ? 163  GLY I N   1 
ATOM   3679 C CA  . GLY C 3  171 ? -2.943  -18.169 0.415   1.00 50.34 ? 163  GLY I CA  1 
ATOM   3680 C C   . GLY C 3  171 ? -2.400  -17.118 -0.533  1.00 50.22 ? 163  GLY I C   1 
ATOM   3681 O O   . GLY C 3  171 ? -1.406  -17.350 -1.222  1.00 50.20 ? 163  GLY I O   1 
ATOM   3682 N N   . LYS C 3  172 ? -3.045  -15.957 -0.567  1.00 49.86 ? 164  LYS I N   1 
ATOM   3683 C CA  . LYS C 3  172 ? -2.617  -14.876 -1.446  1.00 50.36 ? 164  LYS I CA  1 
ATOM   3684 C C   . LYS C 3  172 ? -1.330  -14.218 -0.955  1.00 50.97 ? 164  LYS I C   1 
ATOM   3685 O O   . LYS C 3  172 ? -0.459  -13.866 -1.752  1.00 50.97 ? 164  LYS I O   1 
ATOM   3686 C CB  . LYS C 3  172 ? -3.724  -13.825 -1.563  1.00 50.29 ? 164  LYS I CB  1 
ATOM   3687 C CG  . LYS C 3  172 ? -5.014  -14.350 -2.177  1.00 50.09 ? 164  LYS I CG  1 
ATOM   3688 N N   . ILE C 3  173 ? -1.213  -14.054 0.358   1.00 51.10 ? 165  ILE I N   1 
ATOM   3689 C CA  . ILE C 3  173 ? -0.029  -13.436 0.942   1.00 51.21 ? 165  ILE I CA  1 
ATOM   3690 C C   . ILE C 3  173 ? 0.758   -14.458 1.755   1.00 51.44 ? 165  ILE I C   1 
ATOM   3691 O O   . ILE C 3  173 ? 0.479   -14.681 2.933   1.00 51.62 ? 165  ILE I O   1 
ATOM   3692 C CB  . ILE C 3  173 ? -0.417  -12.249 1.848   1.00 51.30 ? 165  ILE I CB  1 
ATOM   3693 C CG1 . ILE C 3  173 ? -1.213  -11.222 1.035   1.00 51.45 ? 165  ILE I CG1 1 
ATOM   3694 C CG2 . ILE C 3  173 ? 0.833   -11.605 2.431   1.00 51.19 ? 165  ILE I CG2 1 
ATOM   3695 C CD1 . ILE C 3  173 ? -1.684  -10.026 1.833   1.00 52.03 ? 165  ILE I CD1 1 
ATOM   3696 N N   . VAL C 3  174 ? 1.743   -15.076 1.112   1.00 51.50 ? 166  VAL I N   1 
ATOM   3697 C CA  . VAL C 3  174 ? 2.572   -16.084 1.760   1.00 51.52 ? 166  VAL I CA  1 
ATOM   3698 C C   . VAL C 3  174 ? 4.001   -15.596 1.964   1.00 51.52 ? 166  VAL I C   1 
ATOM   3699 O O   . VAL C 3  174 ? 4.456   -14.670 1.292   1.00 51.53 ? 166  VAL I O   1 
ATOM   3700 C CB  . VAL C 3  174 ? 2.612   -17.384 0.930   1.00 51.64 ? 166  VAL I CB  1 
ATOM   3701 C CG1 . VAL C 3  174 ? 1.210   -17.956 0.790   1.00 51.32 ? 166  VAL I CG1 1 
ATOM   3702 C CG2 . VAL C 3  174 ? 3.213   -17.108 -0.440  1.00 51.44 ? 166  VAL I CG2 1 
ATOM   3703 N N   . ASP C 3  175 ? 4.702   -16.232 2.898   1.00 51.88 ? 167  ASP I N   1 
ATOM   3704 C CA  . ASP C 3  175 ? 6.083   -15.882 3.208   1.00 52.24 ? 167  ASP I CA  1 
ATOM   3705 C C   . ASP C 3  175 ? 6.233   -14.398 3.518   1.00 51.67 ? 167  ASP I C   1 
ATOM   3706 O O   . ASP C 3  175 ? 7.112   -13.725 2.979   1.00 51.78 ? 167  ASP I O   1 
ATOM   3707 C CB  . ASP C 3  175 ? 6.997   -16.265 2.042   1.00 53.92 ? 167  ASP I CB  1 
ATOM   3708 C CG  . ASP C 3  175 ? 6.999   -17.757 1.772   1.00 55.56 ? 167  ASP I CG  1 
ATOM   3709 O OD1 . ASP C 3  175 ? 7.351   -18.528 2.690   1.00 57.03 ? 167  ASP I OD1 1 
ATOM   3710 O OD2 . ASP C 3  175 ? 6.647   -18.160 0.643   1.00 56.81 ? 167  ASP I OD2 1 
ATOM   3711 N N   . LEU C 3  176 ? 5.368   -13.894 4.391   1.00 51.04 ? 168  LEU I N   1 
ATOM   3712 C CA  . LEU C 3  176 ? 5.404   -12.491 4.781   1.00 50.59 ? 168  LEU I CA  1 
ATOM   3713 C C   . LEU C 3  176 ? 6.796   -12.134 5.289   1.00 51.05 ? 168  LEU I C   1 
ATOM   3714 O O   . LEU C 3  176 ? 7.397   -11.154 4.851   1.00 50.58 ? 168  LEU I O   1 
ATOM   3715 C CB  . LEU C 3  176 ? 4.371   -12.224 5.878   1.00 49.86 ? 168  LEU I CB  1 
ATOM   3716 C CG  . LEU C 3  176 ? 4.251   -10.778 6.364   1.00 49.33 ? 168  LEU I CG  1 
ATOM   3717 C CD1 . LEU C 3  176 ? 3.743   -9.902  5.232   1.00 49.15 ? 168  LEU I CD1 1 
ATOM   3718 C CD2 . LEU C 3  176 ? 3.308   -10.710 7.551   1.00 49.45 ? 168  LEU I CD2 1 
ATOM   3719 N N   . LEU C 3  177 ? 7.302   -12.942 6.216   1.00 51.67 ? 169  LEU I N   1 
ATOM   3720 C CA  . LEU C 3  177 ? 8.624   -12.721 6.791   1.00 52.70 ? 169  LEU I CA  1 
ATOM   3721 C C   . LEU C 3  177 ? 9.652   -13.624 6.121   1.00 53.90 ? 169  LEU I C   1 
ATOM   3722 O O   . LEU C 3  177 ? 9.397   -14.807 5.893   1.00 53.82 ? 169  LEU I O   1 
ATOM   3723 C CB  . LEU C 3  177 ? 8.600   -13.000 8.297   1.00 50.94 ? 169  LEU I CB  1 
ATOM   3724 C CG  . LEU C 3  177 ? 7.605   -12.188 9.130   1.00 50.37 ? 169  LEU I CG  1 
ATOM   3725 C CD1 . LEU C 3  177 ? 7.731   -12.577 10.593  1.00 50.06 ? 169  LEU I CD1 1 
ATOM   3726 C CD2 . LEU C 3  177 ? 7.871   -10.702 8.950   1.00 50.04 ? 169  LEU I CD2 1 
ATOM   3727 N N   . LYS C 3  178 ? 10.815  -13.060 5.808   1.00 55.67 ? 170  LYS I N   1 
ATOM   3728 C CA  . LYS C 3  178 ? 11.881  -13.816 5.163   1.00 57.45 ? 170  LYS I CA  1 
ATOM   3729 C C   . LYS C 3  178 ? 13.095  -13.959 6.074   1.00 58.20 ? 170  LYS I C   1 
ATOM   3730 O O   . LYS C 3  178 ? 13.902  -14.875 5.909   1.00 58.83 ? 170  LYS I O   1 
ATOM   3731 C CB  . LYS C 3  178 ? 12.288  -13.134 3.854   1.00 58.03 ? 170  LYS I CB  1 
ATOM   3732 C CG  . LYS C 3  178 ? 11.189  -13.118 2.799   1.00 58.84 ? 170  LYS I CG  1 
ATOM   3733 C CD  . LYS C 3  178 ? 11.640  -12.398 1.538   1.00 59.57 ? 170  LYS I CD  1 
ATOM   3734 C CE  . LYS C 3  178 ? 10.588  -12.486 0.442   1.00 60.37 ? 170  LYS I CE  1 
ATOM   3735 N NZ  . LYS C 3  178 ? 9.288   -11.894 0.857   1.00 60.50 ? 170  LYS I NZ  1 
ATOM   3736 N N   . ASN C 3  179 ? 13.217  -13.049 7.035   1.00 58.66 ? 171  ASN I N   1 
ATOM   3737 C CA  . ASN C 3  179 ? 14.327  -13.063 7.983   1.00 59.14 ? 171  ASN I CA  1 
ATOM   3738 C C   . ASN C 3  179 ? 13.894  -12.414 9.294   1.00 59.00 ? 171  ASN I C   1 
ATOM   3739 O O   . ASN C 3  179 ? 13.828  -11.189 9.398   1.00 59.56 ? 171  ASN I O   1 
ATOM   3740 C CB  . ASN C 3  179 ? 15.525  -12.304 7.408   1.00 60.00 ? 171  ASN I CB  1 
ATOM   3741 C CG  . ASN C 3  179 ? 16.034  -12.910 6.116   1.00 61.01 ? 171  ASN I CG  1 
ATOM   3742 O OD1 . ASN C 3  179 ? 16.492  -14.053 6.090   1.00 61.50 ? 171  ASN I OD1 1 
ATOM   3743 N ND2 . ASN C 3  179 ? 15.953  -12.145 5.033   1.00 61.68 ? 171  ASN I ND2 1 
ATOM   3744 N N   . LEU C 3  180 ? 13.602  -13.238 10.295  1.00 58.24 ? 172  LEU I N   1 
ATOM   3745 C CA  . LEU C 3  180 ? 13.166  -12.729 11.589  1.00 57.14 ? 172  LEU I CA  1 
ATOM   3746 C C   . LEU C 3  180 ? 14.345  -12.550 12.540  1.00 56.45 ? 172  LEU I C   1 
ATOM   3747 O O   . LEU C 3  180 ? 14.934  -13.526 13.003  1.00 56.66 ? 172  LEU I O   1 
ATOM   3748 C CB  . LEU C 3  180 ? 12.141  -13.686 12.210  1.00 57.09 ? 172  LEU I CB  1 
ATOM   3749 C CG  . LEU C 3  180 ? 11.203  -13.139 13.293  1.00 56.95 ? 172  LEU I CG  1 
ATOM   3750 C CD1 . LEU C 3  180 ? 10.255  -14.240 13.733  1.00 56.54 ? 172  LEU I CD1 1 
ATOM   3751 C CD2 . LEU C 3  180 ? 11.995  -12.619 14.476  1.00 57.43 ? 172  LEU I CD2 1 
ATOM   3752 N N   . ASP C 3  181 ? 14.682  -11.296 12.826  1.00 55.62 ? 173  ASP I N   1 
ATOM   3753 C CA  . ASP C 3  181 ? 15.784  -10.988 13.731  1.00 54.36 ? 173  ASP I CA  1 
ATOM   3754 C C   . ASP C 3  181 ? 15.473  -11.552 15.114  1.00 53.18 ? 173  ASP I C   1 
ATOM   3755 O O   . ASP C 3  181 ? 14.377  -11.360 15.639  1.00 53.60 ? 173  ASP I O   1 
ATOM   3756 C CB  . ASP C 3  181 ? 15.984  -9.473  13.822  1.00 54.75 ? 173  ASP I CB  1 
ATOM   3757 N N   . SER C 3  182 ? 16.441  -12.248 15.701  1.00 51.24 ? 174  SER I N   1 
ATOM   3758 C CA  . SER C 3  182 ? 16.256  -12.848 17.017  1.00 49.13 ? 174  SER I CA  1 
ATOM   3759 C C   . SER C 3  182 ? 15.985  -11.816 18.110  1.00 46.76 ? 174  SER I C   1 
ATOM   3760 O O   . SER C 3  182 ? 16.237  -10.623 17.935  1.00 46.37 ? 174  SER I O   1 
ATOM   3761 C CB  . SER C 3  182 ? 17.488  -13.679 17.393  1.00 50.61 ? 174  SER I CB  1 
ATOM   3762 O OG  . SER C 3  182 ? 18.654  -12.874 17.450  1.00 52.21 ? 174  SER I OG  1 
ATOM   3763 N N   . ASN C 3  183 ? 15.462  -12.297 19.235  1.00 43.65 ? 175  ASN I N   1 
ATOM   3764 C CA  . ASN C 3  183 ? 15.152  -11.462 20.391  1.00 40.87 ? 175  ASN I CA  1 
ATOM   3765 C C   . ASN C 3  183 ? 14.107  -10.375 20.145  1.00 37.95 ? 175  ASN I C   1 
ATOM   3766 O O   . ASN C 3  183 ? 14.124  -9.330  20.799  1.00 36.06 ? 175  ASN I O   1 
ATOM   3767 C CB  . ASN C 3  183 ? 16.432  -10.822 20.936  1.00 43.61 ? 175  ASN I CB  1 
ATOM   3768 C CG  . ASN C 3  183 ? 17.426  -11.848 21.450  1.00 44.96 ? 175  ASN I CG  1 
ATOM   3769 O OD1 . ASN C 3  183 ? 18.457  -11.495 22.023  1.00 47.36 ? 175  ASN I OD1 1 
ATOM   3770 N ND2 . ASN C 3  183 ? 17.123  -13.125 21.244  1.00 45.80 ? 175  ASN I ND2 1 
ATOM   3771 N N   . ALA C 3  184 ? 13.193  -10.619 19.211  1.00 34.12 ? 176  ALA I N   1 
ATOM   3772 C CA  . ALA C 3  184 ? 12.146  -9.645  18.923  1.00 31.54 ? 176  ALA I CA  1 
ATOM   3773 C C   . ALA C 3  184 ? 11.227  -9.526  20.138  1.00 29.34 ? 176  ALA I C   1 
ATOM   3774 O O   . ALA C 3  184 ? 11.078  -10.474 20.913  1.00 27.88 ? 176  ALA I O   1 
ATOM   3775 C CB  . ALA C 3  184 ? 11.345  -10.078 17.696  1.00 30.75 ? 176  ALA I CB  1 
ATOM   3776 N N   . VAL C 3  185 ? 10.615  -8.359  20.301  1.00 25.87 ? 177  VAL I N   1 
ATOM   3777 C CA  . VAL C 3  185 ? 9.714   -8.119  21.421  1.00 24.97 ? 177  VAL I CA  1 
ATOM   3778 C C   . VAL C 3  185 ? 8.283   -8.091  20.910  1.00 23.14 ? 177  VAL I C   1 
ATOM   3779 O O   . VAL C 3  185 ? 7.418   -8.817  21.396  1.00 24.06 ? 177  VAL I O   1 
ATOM   3780 C CB  . VAL C 3  185 ? 10.033  -6.779  22.102  1.00 25.15 ? 177  VAL I CB  1 
ATOM   3781 C CG1 . VAL C 3  185 ? 9.122   -6.573  23.299  1.00 25.39 ? 177  VAL I CG1 1 
ATOM   3782 C CG2 . VAL C 3  185 ? 11.494  -6.756  22.530  1.00 26.08 ? 177  VAL I CG2 1 
ATOM   3783 N N   . VAL C 3  186 ? 8.045   -7.244  19.916  1.00 23.42 ? 178  VAL I N   1 
ATOM   3784 C CA  . VAL C 3  186 ? 6.728   -7.120  19.317  1.00 22.12 ? 178  VAL I CA  1 
ATOM   3785 C C   . VAL C 3  186 ? 6.868   -6.973  17.813  1.00 22.16 ? 178  VAL I C   1 
ATOM   3786 O O   . VAL C 3  186 ? 7.673   -6.180  17.336  1.00 19.84 ? 178  VAL I O   1 
ATOM   3787 C CB  . VAL C 3  186 ? 5.975   -5.890  19.872  1.00 24.76 ? 178  VAL I CB  1 
ATOM   3788 C CG1 . VAL C 3  186 ? 4.741   -5.600  19.040  1.00 25.35 ? 178  VAL I CG1 1 
ATOM   3789 C CG2 . VAL C 3  186 ? 5.575   -6.147  21.313  1.00 26.33 ? 178  VAL I CG2 1 
ATOM   3790 N N   . ILE C 3  187 ? 6.095   -7.760  17.077  1.00 22.05 ? 179  ILE I N   1 
ATOM   3791 C CA  . ILE C 3  187 ? 6.106   -7.693  15.622  1.00 24.94 ? 179  ILE I CA  1 
ATOM   3792 C C   . ILE C 3  187 ? 4.686   -7.418  15.160  1.00 25.40 ? 179  ILE I C   1 
ATOM   3793 O O   . ILE C 3  187 ? 3.775   -8.206  15.411  1.00 23.91 ? 179  ILE I O   1 
ATOM   3794 C CB  . ILE C 3  187 ? 6.574   -9.014  14.972  1.00 25.69 ? 179  ILE I CB  1 
ATOM   3795 C CG1 . ILE C 3  187 ? 8.014   -9.330  15.383  1.00 29.23 ? 179  ILE I CG1 1 
ATOM   3796 C CG2 . ILE C 3  187 ? 6.462   -8.910  13.449  1.00 27.39 ? 179  ILE I CG2 1 
ATOM   3797 C CD1 . ILE C 3  187 ? 9.023   -8.279  14.986  1.00 32.29 ? 179  ILE I CD1 1 
ATOM   3798 N N   . MET C 3  188 ? 4.497   -6.285  14.499  1.00 26.18 ? 180  MET I N   1 
ATOM   3799 C CA  . MET C 3  188 ? 3.188   -5.929  13.991  1.00 27.54 ? 180  MET I CA  1 
ATOM   3800 C C   . MET C 3  188 ? 3.175   -6.225  12.500  1.00 27.74 ? 180  MET I C   1 
ATOM   3801 O O   . MET C 3  188 ? 4.119   -5.888  11.786  1.00 26.06 ? 180  MET I O   1 
ATOM   3802 C CB  . MET C 3  188 ? 2.904   -4.448  14.244  1.00 31.13 ? 180  MET I CB  1 
ATOM   3803 C CG  . MET C 3  188 ? 1.607   -3.950  13.636  1.00 36.30 ? 180  MET I CG  1 
ATOM   3804 S SD  . MET C 3  188 ? 1.110   -2.343  14.287  1.00 43.22 ? 180  MET I SD  1 
ATOM   3805 C CE  . MET C 3  188 ? 2.640   -1.430  14.176  1.00 41.88 ? 180  MET I CE  1 
ATOM   3806 N N   . VAL C 3  189 ? 2.121   -6.886  12.038  1.00 26.11 ? 181  VAL I N   1 
ATOM   3807 C CA  . VAL C 3  189 ? 2.013   -7.204  10.623  1.00 27.35 ? 181  VAL I CA  1 
ATOM   3808 C C   . VAL C 3  189 ? 0.725   -6.639  10.052  1.00 27.74 ? 181  VAL I C   1 
ATOM   3809 O O   . VAL C 3  189 ? -0.332  -6.681  10.688  1.00 28.17 ? 181  VAL I O   1 
ATOM   3810 C CB  . VAL C 3  189 ? 2.058   -8.731  10.371  1.00 27.24 ? 181  VAL I CB  1 
ATOM   3811 C CG1 . VAL C 3  189 ? 3.368   -9.299  10.889  1.00 28.37 ? 181  VAL I CG1 1 
ATOM   3812 C CG2 . VAL C 3  189 ? 0.874   -9.411  11.037  1.00 27.87 ? 181  VAL I CG2 1 
ATOM   3813 N N   . ASN C 3  190 ? 0.832   -6.086  8.851   1.00 27.63 ? 182  ASN I N   1 
ATOM   3814 C CA  . ASN C 3  190 ? -0.307  -5.510  8.158   1.00 28.53 ? 182  ASN I CA  1 
ATOM   3815 C C   . ASN C 3  190 ? -0.215  -6.018  6.727   1.00 28.35 ? 182  ASN I C   1 
ATOM   3816 O O   . ASN C 3  190 ? 0.791   -5.819  6.053   1.00 26.90 ? 182  ASN I O   1 
ATOM   3817 C CB  . ASN C 3  190 ? -0.232  -3.982  8.212   1.00 29.96 ? 182  ASN I CB  1 
ATOM   3818 C CG  . ASN C 3  190 ? -1.280  -3.314  7.350   1.00 33.21 ? 182  ASN I CG  1 
ATOM   3819 O OD1 . ASN C 3  190 ? -1.091  -3.144  6.146   1.00 33.94 ? 182  ASN I OD1 1 
ATOM   3820 N ND2 . ASN C 3  190 ? -2.399  -2.939  7.959   1.00 34.67 ? 182  ASN I ND2 1 
ATOM   3821 N N   . TYR C 3  191 ? -1.261  -6.699  6.275   1.00 29.34 ? 183  TYR I N   1 
ATOM   3822 C CA  . TYR C 3  191 ? -1.264  -7.263  4.935   1.00 29.19 ? 183  TYR I CA  1 
ATOM   3823 C C   . TYR C 3  191 ? -2.572  -6.995  4.211   1.00 29.09 ? 183  TYR I C   1 
ATOM   3824 O O   . TYR C 3  191 ? -3.629  -6.883  4.829   1.00 27.46 ? 183  TYR I O   1 
ATOM   3825 C CB  . TYR C 3  191 ? -1.002  -8.766  5.021   1.00 30.91 ? 183  TYR I CB  1 
ATOM   3826 C CG  . TYR C 3  191 ? -1.833  -9.456  6.079   1.00 34.92 ? 183  TYR I CG  1 
ATOM   3827 C CD1 . TYR C 3  191 ? -3.157  -9.820  5.832   1.00 36.54 ? 183  TYR I CD1 1 
ATOM   3828 C CD2 . TYR C 3  191 ? -1.308  -9.704  7.347   1.00 36.43 ? 183  TYR I CD2 1 
ATOM   3829 C CE1 . TYR C 3  191 ? -3.939  -10.413 6.822   1.00 37.91 ? 183  TYR I CE1 1 
ATOM   3830 C CE2 . TYR C 3  191 ? -2.080  -10.292 8.345   1.00 38.41 ? 183  TYR I CE2 1 
ATOM   3831 C CZ  . TYR C 3  191 ? -3.393  -10.643 8.076   1.00 39.37 ? 183  TYR I CZ  1 
ATOM   3832 O OH  . TYR C 3  191 ? -4.160  -11.216 9.066   1.00 41.13 ? 183  TYR I OH  1 
ATOM   3833 N N   . ILE C 3  192 ? -2.496  -6.885  2.891   1.00 28.25 ? 184  ILE I N   1 
ATOM   3834 C CA  . ILE C 3  192 ? -3.691  -6.626  2.111   1.00 29.25 ? 184  ILE I CA  1 
ATOM   3835 C C   . ILE C 3  192 ? -3.536  -7.111  0.678   1.00 30.28 ? 184  ILE I C   1 
ATOM   3836 O O   . ILE C 3  192 ? -2.545  -6.810  0.011   1.00 29.74 ? 184  ILE I O   1 
ATOM   3837 C CB  . ILE C 3  192 ? -4.035  -5.115  2.117   1.00 29.57 ? 184  ILE I CB  1 
ATOM   3838 C CG1 . ILE C 3  192 ? -5.305  -4.863  1.304   1.00 29.31 ? 184  ILE I CG1 1 
ATOM   3839 C CG2 . ILE C 3  192 ? -2.866  -4.307  1.564   1.00 29.81 ? 184  ILE I CG2 1 
ATOM   3840 C CD1 . ILE C 3  192 ? -5.791  -3.429  1.358   1.00 28.86 ? 184  ILE I CD1 1 
ATOM   3841 N N   . PHE C 3  193 ? -4.509  -7.898  0.229   1.00 32.16 ? 185  PHE I N   1 
ATOM   3842 C CA  . PHE C 3  193 ? -4.518  -8.414  -1.132  1.00 34.09 ? 185  PHE I CA  1 
ATOM   3843 C C   . PHE C 3  193 ? -5.726  -7.807  -1.827  1.00 34.71 ? 185  PHE I C   1 
ATOM   3844 O O   . PHE C 3  193 ? -6.767  -7.599  -1.203  1.00 34.65 ? 185  PHE I O   1 
ATOM   3845 C CB  . PHE C 3  193 ? -4.646  -9.937  -1.151  1.00 35.12 ? 185  PHE I CB  1 
ATOM   3846 C CG  . PHE C 3  193 ? -4.860  -10.501 -2.531  1.00 37.16 ? 185  PHE I CG  1 
ATOM   3847 C CD1 . PHE C 3  193 ? -3.801  -10.606 -3.426  1.00 37.94 ? 185  PHE I CD1 1 
ATOM   3848 C CD2 . PHE C 3  193 ? -6.133  -10.876 -2.952  1.00 38.19 ? 185  PHE I CD2 1 
ATOM   3849 C CE1 . PHE C 3  193 ? -4.006  -11.075 -4.724  1.00 38.73 ? 185  PHE I CE1 1 
ATOM   3850 C CE2 . PHE C 3  193 ? -6.349  -11.345 -4.248  1.00 38.88 ? 185  PHE I CE2 1 
ATOM   3851 C CZ  . PHE C 3  193 ? -5.283  -11.444 -5.134  1.00 38.47 ? 185  PHE I CZ  1 
ATOM   3852 N N   . PHE C 3  194 ? -5.591  -7.526  -3.118  1.00 35.63 ? 186  PHE I N   1 
ATOM   3853 C CA  . PHE C 3  194 ? -6.686  -6.931  -3.867  1.00 36.33 ? 186  PHE I CA  1 
ATOM   3854 C C   . PHE C 3  194 ? -6.676  -7.336  -5.334  1.00 36.92 ? 186  PHE I C   1 
ATOM   3855 O O   . PHE C 3  194 ? -5.625  -7.414  -5.971  1.00 36.20 ? 186  PHE I O   1 
ATOM   3856 C CB  . PHE C 3  194 ? -6.624  -5.406  -3.732  1.00 36.73 ? 186  PHE I CB  1 
ATOM   3857 C CG  . PHE C 3  194 ? -7.650  -4.670  -4.549  1.00 37.12 ? 186  PHE I CG  1 
ATOM   3858 C CD1 . PHE C 3  194 ? -7.449  -4.444  -5.908  1.00 36.94 ? 186  PHE I CD1 1 
ATOM   3859 C CD2 . PHE C 3  194 ? -8.807  -4.177  -3.953  1.00 37.86 ? 186  PHE I CD2 1 
ATOM   3860 C CE1 . PHE C 3  194 ? -8.382  -3.734  -6.662  1.00 37.06 ? 186  PHE I CE1 1 
ATOM   3861 C CE2 . PHE C 3  194 ? -9.750  -3.465  -4.700  1.00 37.88 ? 186  PHE I CE2 1 
ATOM   3862 C CZ  . PHE C 3  194 ? -9.535  -3.243  -6.056  1.00 37.34 ? 186  PHE I CZ  1 
ATOM   3863 N N   . LYS C 3  195 ? -7.868  -7.601  -5.853  1.00 38.11 ? 187  LYS I N   1 
ATOM   3864 C CA  . LYS C 3  195 ? -8.056  -7.987  -7.244  1.00 39.39 ? 187  LYS I CA  1 
ATOM   3865 C C   . LYS C 3  195 ? -9.541  -7.860  -7.541  1.00 39.60 ? 187  LYS I C   1 
ATOM   3866 O O   . LYS C 3  195 ? -10.351 -8.641  -7.042  1.00 40.32 ? 187  LYS I O   1 
ATOM   3867 C CB  . LYS C 3  195 ? -7.598  -9.429  -7.475  1.00 40.09 ? 187  LYS I CB  1 
ATOM   3868 C CG  . LYS C 3  195 ? -7.779  -9.911  -8.909  1.00 40.44 ? 187  LYS I CG  1 
ATOM   3869 C CD  . LYS C 3  195 ? -7.225  -11.316 -9.101  1.00 41.31 ? 187  LYS I CD  1 
ATOM   3870 N N   . ALA C 3  196 ? -9.896  -6.865  -8.345  1.00 39.71 ? 188  ALA I N   1 
ATOM   3871 C CA  . ALA C 3  196 ? -11.289 -6.634  -8.691  1.00 38.64 ? 188  ALA I CA  1 
ATOM   3872 C C   . ALA C 3  196 ? -11.502 -6.646  -10.197 1.00 39.38 ? 188  ALA I C   1 
ATOM   3873 O O   . ALA C 3  196 ? -10.564 -6.455  -10.972 1.00 38.13 ? 188  ALA I O   1 
ATOM   3874 C CB  . ALA C 3  196 ? -11.750 -5.306  -8.113  1.00 37.88 ? 188  ALA I CB  1 
ATOM   3875 N N   . LYS C 3  197 ? -12.746 -6.873  -10.602 1.00 39.10 ? 189  LYS I N   1 
ATOM   3876 C CA  . LYS C 3  197 ? -13.095 -6.897  -12.014 1.00 40.15 ? 189  LYS I CA  1 
ATOM   3877 C C   . LYS C 3  197 ? -13.231 -5.471  -12.525 1.00 38.99 ? 189  LYS I C   1 
ATOM   3878 O O   . LYS C 3  197 ? -13.767 -4.604  -11.833 1.00 39.17 ? 189  LYS I O   1 
ATOM   3879 C CB  . LYS C 3  197 ? -14.420 -7.634  -12.222 1.00 41.38 ? 189  LYS I CB  1 
ATOM   3880 C CG  . LYS C 3  197 ? -14.403 -9.094  -11.811 1.00 43.80 ? 189  LYS I CG  1 
ATOM   3881 C CD  . LYS C 3  197 ? -15.749 -9.752  -12.074 1.00 45.96 ? 189  LYS I CD  1 
ATOM   3882 C CE  . LYS C 3  197 ? -15.703 -11.242 -11.767 1.00 46.93 ? 189  LYS I CE  1 
ATOM   3883 N NZ  . LYS C 3  197 ? -14.664 -11.933 -12.584 1.00 47.50 ? 189  LYS I NZ  1 
ATOM   3884 N N   . TRP C 3  198 ? -12.732 -5.223  -13.730 1.00 39.68 ? 190  TRP I N   1 
ATOM   3885 C CA  . TRP C 3  198 ? -12.840 -3.899  -14.326 1.00 39.40 ? 190  TRP I CA  1 
ATOM   3886 C C   . TRP C 3  198 ? -14.309 -3.680  -14.649 1.00 41.15 ? 190  TRP I C   1 
ATOM   3887 O O   . TRP C 3  198 ? -15.066 -4.638  -14.785 1.00 41.51 ? 190  TRP I O   1 
ATOM   3888 C CB  . TRP C 3  198 ? -12.035 -3.816  -15.625 1.00 37.19 ? 190  TRP I CB  1 
ATOM   3889 C CG  . TRP C 3  198 ? -10.554 -3.902  -15.450 1.00 34.69 ? 190  TRP I CG  1 
ATOM   3890 C CD1 . TRP C 3  198 ? -9.723  -4.856  -15.962 1.00 33.97 ? 190  TRP I CD1 1 
ATOM   3891 C CD2 . TRP C 3  198 ? -9.720  -2.980  -14.743 1.00 33.03 ? 190  TRP I CD2 1 
ATOM   3892 N NE1 . TRP C 3  198 ? -8.422  -4.583  -15.619 1.00 33.04 ? 190  TRP I NE1 1 
ATOM   3893 C CE2 . TRP C 3  198 ? -8.392  -3.436  -14.870 1.00 33.56 ? 190  TRP I CE2 1 
ATOM   3894 C CE3 . TRP C 3  198 ? -9.967  -1.809  -14.014 1.00 32.44 ? 190  TRP I CE3 1 
ATOM   3895 C CZ2 . TRP C 3  198 ? -7.309  -2.762  -14.294 1.00 32.59 ? 190  TRP I CZ2 1 
ATOM   3896 C CZ3 . TRP C 3  198 ? -8.890  -1.139  -13.441 1.00 32.65 ? 190  TRP I CZ3 1 
ATOM   3897 C CH2 . TRP C 3  198 ? -7.578  -1.619  -13.586 1.00 32.49 ? 190  TRP I CH2 1 
ATOM   3898 N N   . GLU C 3  199 ? -14.715 -2.421  -14.759 1.00 42.55 ? 191  GLU I N   1 
ATOM   3899 C CA  . GLU C 3  199 ? -16.095 -2.108  -15.099 1.00 43.85 ? 191  GLU I CA  1 
ATOM   3900 C C   . GLU C 3  199 ? -16.311 -2.694  -16.491 1.00 43.66 ? 191  GLU I C   1 
ATOM   3901 O O   . GLU C 3  199 ? -17.314 -3.353  -16.765 1.00 43.88 ? 191  GLU I O   1 
ATOM   3902 C CB  . GLU C 3  199 ? -16.289 -0.593  -15.133 1.00 45.53 ? 191  GLU I CB  1 
ATOM   3903 C CG  . GLU C 3  199 ? -17.716 -0.136  -15.357 1.00 49.12 ? 191  GLU I CG  1 
ATOM   3904 C CD  . GLU C 3  199 ? -17.815 1.369   -15.505 1.00 50.72 ? 191  GLU I CD  1 
ATOM   3905 O OE1 . GLU C 3  199 ? -17.329 1.899   -16.526 1.00 52.65 ? 191  GLU I OE1 1 
ATOM   3906 O OE2 . GLU C 3  199 ? -18.370 2.025   -14.598 1.00 52.35 ? 191  GLU I OE2 1 
ATOM   3907 N N   . THR C 3  200 ? -15.334 -2.451  -17.358 1.00 43.00 ? 192  THR I N   1 
ATOM   3908 C CA  . THR C 3  200 ? -15.356 -2.934  -18.729 1.00 43.40 ? 192  THR I CA  1 
ATOM   3909 C C   . THR C 3  200 ? -14.145 -3.838  -18.965 1.00 43.18 ? 192  THR I C   1 
ATOM   3910 O O   . THR C 3  200 ? -13.003 -3.438  -18.745 1.00 42.58 ? 192  THR I O   1 
ATOM   3911 C CB  . THR C 3  200 ? -15.356 -1.745  -19.722 1.00 43.65 ? 192  THR I CB  1 
ATOM   3912 O OG1 . THR C 3  200 ? -14.893 -2.183  -21.000 1.00 45.24 ? 192  THR I OG1 1 
ATOM   3913 C CG2 . THR C 3  200 ? -14.471 -0.621  -19.221 1.00 44.95 ? 192  THR I CG2 1 
ATOM   3914 N N   . SER C 3  201 ? -14.410 -5.062  -19.410 1.00 44.23 ? 193  SER I N   1 
ATOM   3915 C CA  . SER C 3  201 ? -13.368 -6.057  -19.651 1.00 44.81 ? 193  SER I CA  1 
ATOM   3916 C C   . SER C 3  201 ? -12.396 -5.769  -20.787 1.00 45.30 ? 193  SER I C   1 
ATOM   3917 O O   . SER C 3  201 ? -12.668 -4.969  -21.683 1.00 45.56 ? 193  SER I O   1 
ATOM   3918 C CB  . SER C 3  201 ? -14.007 -7.425  -19.913 1.00 45.68 ? 193  SER I CB  1 
ATOM   3919 O OG  . SER C 3  201 ? -14.879 -7.802  -18.866 1.00 47.35 ? 193  SER I OG  1 
ATOM   3920 N N   . PHE C 3  202 ? -11.253 -6.445  -20.726 1.00 45.77 ? 194  PHE I N   1 
ATOM   3921 C CA  . PHE C 3  202 ? -10.210 -6.357  -21.741 1.00 46.37 ? 194  PHE I CA  1 
ATOM   3922 C C   . PHE C 3  202 ? -10.314 -7.687  -22.479 1.00 48.10 ? 194  PHE I C   1 
ATOM   3923 O O   . PHE C 3  202 ? -10.266 -8.744  -21.852 1.00 47.84 ? 194  PHE I O   1 
ATOM   3924 C CB  . PHE C 3  202 ? -8.823  -6.258  -21.095 1.00 45.37 ? 194  PHE I CB  1 
ATOM   3925 C CG  . PHE C 3  202 ? -8.407  -4.859  -20.731 1.00 43.58 ? 194  PHE I CG  1 
ATOM   3926 C CD1 . PHE C 3  202 ? -8.006  -3.960  -21.713 1.00 42.70 ? 194  PHE I CD1 1 
ATOM   3927 C CD2 . PHE C 3  202 ? -8.395  -4.446  -19.402 1.00 43.55 ? 194  PHE I CD2 1 
ATOM   3928 C CE1 . PHE C 3  202 ? -7.597  -2.672  -21.379 1.00 41.83 ? 194  PHE I CE1 1 
ATOM   3929 C CE2 . PHE C 3  202 ? -7.988  -3.160  -19.058 1.00 42.33 ? 194  PHE I CE2 1 
ATOM   3930 C CZ  . PHE C 3  202 ? -7.588  -2.271  -20.048 1.00 42.59 ? 194  PHE I CZ  1 
ATOM   3931 N N   . ASN C 3  203 ? -10.471 -7.646  -23.797 1.00 50.11 ? 195  ASN I N   1 
ATOM   3932 C CA  . ASN C 3  203 ? -10.576 -8.882  -24.565 1.00 52.41 ? 195  ASN I CA  1 
ATOM   3933 C C   . ASN C 3  203 ? -9.293  -9.688  -24.391 1.00 53.23 ? 195  ASN I C   1 
ATOM   3934 O O   . ASN C 3  203 ? -8.233  -9.276  -24.858 1.00 52.33 ? 195  ASN I O   1 
ATOM   3935 C CB  . ASN C 3  203 ? -10.789 -8.572  -26.048 1.00 53.55 ? 195  ASN I CB  1 
ATOM   3936 C CG  . ASN C 3  203 ? -11.055 -9.819  -26.871 1.00 54.49 ? 195  ASN I CG  1 
ATOM   3937 O OD1 . ASN C 3  203 ? -11.079 -9.770  -28.101 1.00 55.27 ? 195  ASN I OD1 1 
ATOM   3938 N ND2 . ASN C 3  203 ? -11.264 -10.943 -26.194 1.00 54.13 ? 195  ASN I ND2 1 
ATOM   3939 N N   . HIS C 3  204 ? -9.388  -10.835 -23.722 1.00 55.10 ? 196  HIS I N   1 
ATOM   3940 C CA  . HIS C 3  204 ? -8.210  -11.667 -23.499 1.00 57.33 ? 196  HIS I CA  1 
ATOM   3941 C C   . HIS C 3  204 ? -7.602  -12.119 -24.822 1.00 57.95 ? 196  HIS I C   1 
ATOM   3942 O O   . HIS C 3  204 ? -6.516  -12.697 -24.855 1.00 58.76 ? 196  HIS I O   1 
ATOM   3943 C CB  . HIS C 3  204 ? -8.554  -12.881 -22.620 1.00 58.51 ? 196  HIS I CB  1 
ATOM   3944 C CG  . HIS C 3  204 ? -9.474  -13.874 -23.265 1.00 60.20 ? 196  HIS I CG  1 
ATOM   3945 N ND1 . HIS C 3  204 ? -9.897  -15.016 -22.619 1.00 60.74 ? 196  HIS I ND1 1 
ATOM   3946 C CD2 . HIS C 3  204 ? -10.040 -13.908 -24.495 1.00 60.96 ? 196  HIS I CD2 1 
ATOM   3947 C CE1 . HIS C 3  204 ? -10.682 -15.711 -23.423 1.00 60.95 ? 196  HIS I CE1 1 
ATOM   3948 N NE2 . HIS C 3  204 ? -10.785 -15.060 -24.568 1.00 61.23 ? 196  HIS I NE2 1 
ATOM   3949 N N   . LYS C 3  205 ? -8.314  -11.848 -25.911 1.00 58.74 ? 197  LYS I N   1 
ATOM   3950 C CA  . LYS C 3  205 ? -7.852  -12.203 -27.247 1.00 59.25 ? 197  LYS I CA  1 
ATOM   3951 C C   . LYS C 3  205 ? -7.084  -11.018 -27.820 1.00 59.20 ? 197  LYS I C   1 
ATOM   3952 O O   . LYS C 3  205 ? -6.497  -11.101 -28.899 1.00 59.87 ? 197  LYS I O   1 
ATOM   3953 C CB  . LYS C 3  205 ? -9.043  -12.541 -28.149 1.00 59.30 ? 197  LYS I CB  1 
ATOM   3954 N N   . GLY C 3  206 ? -7.103  -9.911  -27.084 1.00 59.30 ? 198  GLY I N   1 
ATOM   3955 C CA  . GLY C 3  206 ? -6.400  -8.715  -27.510 1.00 58.83 ? 198  GLY I CA  1 
ATOM   3956 C C   . GLY C 3  206 ? -5.097  -8.578  -26.746 1.00 58.56 ? 198  GLY I C   1 
ATOM   3957 O O   . GLY C 3  206 ? -4.225  -7.788  -27.111 1.00 58.73 ? 198  GLY I O   1 
ATOM   3958 N N   . THR C 3  207 ? -4.969  -9.356  -25.676 1.00 58.07 ? 199  THR I N   1 
ATOM   3959 C CA  . THR C 3  207 ? -3.768  -9.335  -24.853 1.00 57.49 ? 199  THR I CA  1 
ATOM   3960 C C   . THR C 3  207 ? -2.648  -10.046 -25.601 1.00 57.26 ? 199  THR I C   1 
ATOM   3961 O O   . THR C 3  207 ? -2.790  -11.204 -25.993 1.00 56.94 ? 199  THR I O   1 
ATOM   3962 C CB  . THR C 3  207 ? -4.001  -10.049 -23.507 1.00 57.38 ? 199  THR I CB  1 
ATOM   3963 O OG1 . THR C 3  207 ? -5.113  -9.447  -22.834 1.00 56.79 ? 199  THR I OG1 1 
ATOM   3964 C CG2 . THR C 3  207 ? -2.765  -9.940  -22.627 1.00 57.16 ? 199  THR I CG2 1 
ATOM   3965 N N   . GLN C 3  208 ? -1.536  -9.347  -25.799 1.00 56.99 ? 200  GLN I N   1 
ATOM   3966 C CA  . GLN C 3  208 ? -0.402  -9.915  -26.512 1.00 57.21 ? 200  GLN I CA  1 
ATOM   3967 C C   . GLN C 3  208 ? 0.898   -9.434  -25.877 1.00 56.50 ? 200  GLN I C   1 
ATOM   3968 O O   . GLN C 3  208 ? 1.014   -8.274  -25.482 1.00 56.78 ? 200  GLN I O   1 
ATOM   3969 C CB  . GLN C 3  208 ? -0.461  -9.495  -27.983 1.00 57.94 ? 200  GLN I CB  1 
ATOM   3970 C CG  . GLN C 3  208 ? 0.332   -10.377 -28.925 1.00 59.86 ? 200  GLN I CG  1 
ATOM   3971 C CD  . GLN C 3  208 ? 0.145   -9.981  -30.376 1.00 60.56 ? 200  GLN I CD  1 
ATOM   3972 O OE1 . GLN C 3  208 ? 0.617   -8.931  -30.813 1.00 61.37 ? 200  GLN I OE1 1 
ATOM   3973 N NE2 . GLN C 3  208 ? -0.557  -10.818 -31.131 1.00 61.70 ? 200  GLN I NE2 1 
ATOM   3974 N N   . GLU C 3  209 ? 1.876   -10.328 -25.782 1.00 55.50 ? 201  GLU I N   1 
ATOM   3975 C CA  . GLU C 3  209 ? 3.160   -9.993  -25.181 1.00 54.51 ? 201  GLU I CA  1 
ATOM   3976 C C   . GLU C 3  209 ? 3.897   -8.928  -25.989 1.00 53.24 ? 201  GLU I C   1 
ATOM   3977 O O   . GLU C 3  209 ? 4.079   -9.067  -27.196 1.00 52.85 ? 201  GLU I O   1 
ATOM   3978 C CB  . GLU C 3  209 ? 4.014   -11.257 -25.053 1.00 55.81 ? 201  GLU I CB  1 
ATOM   3979 C CG  . GLU C 3  209 ? 5.211   -11.108 -24.133 1.00 57.07 ? 201  GLU I CG  1 
ATOM   3980 C CD  . GLU C 3  209 ? 5.646   -12.430 -23.532 1.00 57.90 ? 201  GLU I CD  1 
ATOM   3981 O OE1 . GLU C 3  209 ? 6.029   -13.340 -24.297 1.00 58.47 ? 201  GLU I OE1 1 
ATOM   3982 O OE2 . GLU C 3  209 ? 5.601   -12.560 -22.291 1.00 58.77 ? 201  GLU I OE2 1 
ATOM   3983 N N   . GLN C 3  210 ? 4.315   -7.863  -25.310 1.00 51.80 ? 202  GLN I N   1 
ATOM   3984 C CA  . GLN C 3  210 ? 5.024   -6.755  -25.944 1.00 50.29 ? 202  GLN I CA  1 
ATOM   3985 C C   . GLN C 3  210 ? 6.326   -6.407  -25.232 1.00 48.58 ? 202  GLN I C   1 
ATOM   3986 O O   . GLN C 3  210 ? 6.656   -6.975  -24.193 1.00 48.16 ? 202  GLN I O   1 
ATOM   3987 C CB  . GLN C 3  210 ? 4.143   -5.503  -25.963 1.00 51.62 ? 202  GLN I CB  1 
ATOM   3988 C CG  . GLN C 3  210 ? 3.540   -5.153  -27.309 1.00 52.70 ? 202  GLN I CG  1 
ATOM   3989 C CD  . GLN C 3  210 ? 2.854   -3.797  -27.292 1.00 52.59 ? 202  GLN I CD  1 
ATOM   3990 O OE1 . GLN C 3  210 ? 3.472   -2.779  -26.977 1.00 52.61 ? 202  GLN I OE1 1 
ATOM   3991 N NE2 . GLN C 3  210 ? 1.571   -3.778  -27.632 1.00 53.25 ? 202  GLN I NE2 1 
ATOM   3992 N N   . ASP C 3  211 ? 7.052   -5.453  -25.804 1.00 46.89 ? 203  ASP I N   1 
ATOM   3993 C CA  . ASP C 3  211 ? 8.315   -4.985  -25.247 1.00 46.00 ? 203  ASP I CA  1 
ATOM   3994 C C   . ASP C 3  211 ? 8.061   -3.949  -24.154 1.00 44.96 ? 203  ASP I C   1 
ATOM   3995 O O   . ASP C 3  211 ? 7.225   -3.061  -24.313 1.00 44.96 ? 203  ASP I O   1 
ATOM   3996 C CB  . ASP C 3  211 ? 9.166   -4.338  -26.345 1.00 47.15 ? 203  ASP I CB  1 
ATOM   3997 C CG  . ASP C 3  211 ? 10.379  -5.170  -26.723 1.00 48.90 ? 203  ASP I CG  1 
ATOM   3998 O OD1 . ASP C 3  211 ? 11.164  -4.708  -27.578 1.00 49.07 ? 203  ASP I OD1 1 
ATOM   3999 O OD2 . ASP C 3  211 ? 10.553  -6.277  -26.170 1.00 50.05 ? 203  ASP I OD2 1 
ATOM   4000 N N   . PHE C 3  212 ? 8.778   -4.070  -23.043 1.00 43.59 ? 204  PHE I N   1 
ATOM   4001 C CA  . PHE C 3  212 ? 8.649   -3.119  -21.946 1.00 41.79 ? 204  PHE I CA  1 
ATOM   4002 C C   . PHE C 3  212 ? 10.040  -2.579  -21.654 1.00 41.29 ? 204  PHE I C   1 
ATOM   4003 O O   . PHE C 3  212 ? 10.966  -3.344  -21.382 1.00 41.96 ? 204  PHE I O   1 
ATOM   4004 C CB  . PHE C 3  212 ? 8.092   -3.790  -20.688 1.00 41.02 ? 204  PHE I CB  1 
ATOM   4005 C CG  . PHE C 3  212 ? 7.747   -2.819  -19.593 1.00 38.55 ? 204  PHE I CG  1 
ATOM   4006 C CD1 . PHE C 3  212 ? 6.483   -2.241  -19.531 1.00 38.83 ? 204  PHE I CD1 1 
ATOM   4007 C CD2 . PHE C 3  212 ? 8.697   -2.451  -18.645 1.00 38.74 ? 204  PHE I CD2 1 
ATOM   4008 C CE1 . PHE C 3  212 ? 6.170   -1.307  -18.540 1.00 36.82 ? 204  PHE I CE1 1 
ATOM   4009 C CE2 . PHE C 3  212 ? 8.396   -1.518  -17.651 1.00 38.00 ? 204  PHE I CE2 1 
ATOM   4010 C CZ  . PHE C 3  212 ? 7.128   -0.946  -17.600 1.00 36.73 ? 204  PHE I CZ  1 
ATOM   4011 N N   . TYR C 3  213 ? 10.185  -1.260  -21.707 1.00 40.78 ? 205  TYR I N   1 
ATOM   4012 C CA  . TYR C 3  213 ? 11.476  -0.632  -21.468 1.00 40.97 ? 205  TYR I CA  1 
ATOM   4013 C C   . TYR C 3  213 ? 11.696  -0.209  -20.019 1.00 40.94 ? 205  TYR I C   1 
ATOM   4014 O O   . TYR C 3  213 ? 11.407  0.928   -19.651 1.00 39.97 ? 205  TYR I O   1 
ATOM   4015 C CB  . TYR C 3  213 ? 11.643  0.590   -22.379 1.00 42.32 ? 205  TYR I CB  1 
ATOM   4016 C CG  . TYR C 3  213 ? 11.524  0.287   -23.859 1.00 44.65 ? 205  TYR I CG  1 
ATOM   4017 C CD1 . TYR C 3  213 ? 10.300  -0.079  -24.423 1.00 44.97 ? 205  TYR I CD1 1 
ATOM   4018 C CD2 . TYR C 3  213 ? 12.637  0.365   -24.697 1.00 45.40 ? 205  TYR I CD2 1 
ATOM   4019 C CE1 . TYR C 3  213 ? 10.186  -0.360  -25.783 1.00 45.38 ? 205  TYR I CE1 1 
ATOM   4020 C CE2 . TYR C 3  213 ? 12.535  0.086   -26.059 1.00 45.84 ? 205  TYR I CE2 1 
ATOM   4021 C CZ  . TYR C 3  213 ? 11.307  -0.275  -26.595 1.00 46.73 ? 205  TYR I CZ  1 
ATOM   4022 O OH  . TYR C 3  213 ? 11.200  -0.552  -27.940 1.00 46.86 ? 205  TYR I OH  1 
ATOM   4023 N N   . VAL C 3  214 ? 12.211  -1.123  -19.199 1.00 40.16 ? 206  VAL I N   1 
ATOM   4024 C CA  . VAL C 3  214 ? 12.486  -0.808  -17.801 1.00 40.16 ? 206  VAL I CA  1 
ATOM   4025 C C   . VAL C 3  214 ? 13.377  0.429   -17.804 1.00 40.49 ? 206  VAL I C   1 
ATOM   4026 O O   . VAL C 3  214 ? 13.285  1.289   -16.928 1.00 39.73 ? 206  VAL I O   1 
ATOM   4027 C CB  . VAL C 3  214 ? 13.226  -1.967  -17.101 1.00 39.37 ? 206  VAL I CB  1 
ATOM   4028 C CG1 . VAL C 3  214 ? 13.486  -1.617  -15.646 1.00 39.81 ? 206  VAL I CG1 1 
ATOM   4029 C CG2 . VAL C 3  214 ? 12.405  -3.242  -17.203 1.00 39.40 ? 206  VAL I CG2 1 
ATOM   4030 N N   . THR C 3  215 ? 14.242  0.497   -18.811 1.00 41.97 ? 207  THR I N   1 
ATOM   4031 C CA  . THR C 3  215 ? 15.153  1.621   -19.003 1.00 43.41 ? 207  THR I CA  1 
ATOM   4032 C C   . THR C 3  215 ? 15.341  1.756   -20.508 1.00 44.11 ? 207  THR I C   1 
ATOM   4033 O O   . THR C 3  215 ? 14.865  0.917   -21.272 1.00 43.29 ? 207  THR I O   1 
ATOM   4034 C CB  . THR C 3  215 ? 16.535  1.370   -18.362 1.00 43.96 ? 207  THR I CB  1 
ATOM   4035 O OG1 . THR C 3  215 ? 17.175  0.270   -19.020 1.00 44.71 ? 207  THR I OG1 1 
ATOM   4036 C CG2 . THR C 3  215 ? 16.389  1.058   -16.882 1.00 44.48 ? 207  THR I CG2 1 
ATOM   4037 N N   . SER C 3  216 ? 16.030  2.806   -20.935 1.00 45.67 ? 208  SER I N   1 
ATOM   4038 C CA  . SER C 3  216 ? 16.266  3.013   -22.357 1.00 47.62 ? 208  SER I CA  1 
ATOM   4039 C C   . SER C 3  216 ? 17.128  1.889   -22.924 1.00 48.84 ? 208  SER I C   1 
ATOM   4040 O O   . SER C 3  216 ? 17.152  1.662   -24.134 1.00 49.35 ? 208  SER I O   1 
ATOM   4041 C CB  . SER C 3  216 ? 16.957  4.359   -22.587 1.00 47.68 ? 208  SER I CB  1 
ATOM   4042 N N   . GLU C 3  217 ? 17.826  1.177   -22.042 1.00 49.84 ? 209  GLU I N   1 
ATOM   4043 C CA  . GLU C 3  217 ? 18.702  0.089   -22.465 1.00 50.54 ? 209  GLU I CA  1 
ATOM   4044 C C   . GLU C 3  217 ? 18.195  -1.307  -22.111 1.00 51.07 ? 209  GLU I C   1 
ATOM   4045 O O   . GLU C 3  217 ? 18.499  -2.277  -22.808 1.00 51.26 ? 209  GLU I O   1 
ATOM   4046 C CB  . GLU C 3  217 ? 20.098  0.285   -21.868 1.00 50.14 ? 209  GLU I CB  1 
ATOM   4047 N N   . THR C 3  218 ? 17.425  -1.411  -21.032 1.00 51.07 ? 210  THR I N   1 
ATOM   4048 C CA  . THR C 3  218 ? 16.899  -2.702  -20.598 1.00 51.10 ? 210  THR I CA  1 
ATOM   4049 C C   . THR C 3  218 ? 15.467  -2.926  -21.072 1.00 51.09 ? 210  THR I C   1 
ATOM   4050 O O   . THR C 3  218 ? 14.564  -2.158  -20.738 1.00 51.72 ? 210  THR I O   1 
ATOM   4051 C CB  . THR C 3  218 ? 16.938  -2.823  -19.063 1.00 51.22 ? 210  THR I CB  1 
ATOM   4052 O OG1 . THR C 3  218 ? 18.273  -2.588  -18.600 1.00 52.13 ? 210  THR I OG1 1 
ATOM   4053 C CG2 . THR C 3  218 ? 16.497  -4.213  -18.627 1.00 51.52 ? 210  THR I CG2 1 
ATOM   4054 N N   . VAL C 3  219 ? 15.267  -3.987  -21.849 1.00 50.59 ? 211  VAL I N   1 
ATOM   4055 C CA  . VAL C 3  219 ? 13.948  -4.318  -22.375 1.00 50.22 ? 211  VAL I CA  1 
ATOM   4056 C C   . VAL C 3  219 ? 13.484  -5.687  -21.886 1.00 50.25 ? 211  VAL I C   1 
ATOM   4057 O O   . VAL C 3  219 ? 14.284  -6.615  -21.761 1.00 50.42 ? 211  VAL I O   1 
ATOM   4058 C CB  . VAL C 3  219 ? 13.953  -4.321  -23.921 1.00 50.48 ? 211  VAL I CB  1 
ATOM   4059 C CG1 . VAL C 3  219 ? 12.578  -4.695  -24.447 1.00 50.43 ? 211  VAL I CG1 1 
ATOM   4060 C CG2 . VAL C 3  219 ? 14.366  -2.954  -24.443 1.00 49.93 ? 211  VAL I CG2 1 
ATOM   4061 N N   . VAL C 3  220 ? 12.188  -5.806  -21.613 1.00 49.19 ? 212  VAL I N   1 
ATOM   4062 C CA  . VAL C 3  220 ? 11.609  -7.058  -21.139 1.00 48.87 ? 212  VAL I CA  1 
ATOM   4063 C C   . VAL C 3  220 ? 10.286  -7.339  -21.847 1.00 48.05 ? 212  VAL I C   1 
ATOM   4064 O O   . VAL C 3  220 ? 9.582   -6.416  -22.253 1.00 48.39 ? 212  VAL I O   1 
ATOM   4065 C CB  . VAL C 3  220 ? 11.352  -7.007  -19.613 1.00 49.52 ? 212  VAL I CB  1 
ATOM   4066 C CG1 . VAL C 3  220 ? 10.780  -8.332  -19.132 1.00 50.19 ? 212  VAL I CG1 1 
ATOM   4067 C CG2 . VAL C 3  220 ? 12.645  -6.686  -18.880 1.00 49.73 ? 212  VAL I CG2 1 
ATOM   4068 N N   . ARG C 3  221 ? 9.956   -8.618  -21.997 1.00 47.11 ? 213  ARG I N   1 
ATOM   4069 C CA  . ARG C 3  221 ? 8.711   -9.017  -22.647 1.00 46.86 ? 213  ARG I CA  1 
ATOM   4070 C C   . ARG C 3  221 ? 7.625   -9.160  -21.591 1.00 46.74 ? 213  ARG I C   1 
ATOM   4071 O O   . ARG C 3  221 ? 7.797   -9.888  -20.613 1.00 47.05 ? 213  ARG I O   1 
ATOM   4072 C CB  . ARG C 3  221 ? 8.891   -10.353 -23.374 1.00 47.05 ? 213  ARG I CB  1 
ATOM   4073 C CG  . ARG C 3  221 ? 9.992   -10.354 -24.419 1.00 47.28 ? 213  ARG I CG  1 
ATOM   4074 C CD  . ARG C 3  221 ? 9.688   -9.381  -25.544 1.00 47.65 ? 213  ARG I CD  1 
ATOM   4075 N NE  . ARG C 3  221 ? 8.488   -9.755  -26.286 1.00 47.58 ? 213  ARG I NE  1 
ATOM   4076 C CZ  . ARG C 3  221 ? 7.988   -9.048  -27.295 1.00 48.61 ? 213  ARG I CZ  1 
ATOM   4077 N NH1 . ARG C 3  221 ? 6.891   -9.459  -27.918 1.00 47.18 ? 213  ARG I NH1 1 
ATOM   4078 N NH2 . ARG C 3  221 ? 8.585   -7.926  -27.678 1.00 48.65 ? 213  ARG I NH2 1 
ATOM   4079 N N   . VAL C 3  222 ? 6.508   -8.467  -21.787 1.00 45.58 ? 214  VAL I N   1 
ATOM   4080 C CA  . VAL C 3  222 ? 5.408   -8.526  -20.833 1.00 45.33 ? 214  VAL I CA  1 
ATOM   4081 C C   . VAL C 3  222 ? 4.061   -8.609  -21.540 1.00 44.73 ? 214  VAL I C   1 
ATOM   4082 O O   . VAL C 3  222 ? 3.872   -8.014  -22.600 1.00 45.92 ? 214  VAL I O   1 
ATOM   4083 C CB  . VAL C 3  222 ? 5.395   -7.279  -19.920 1.00 45.52 ? 214  VAL I CB  1 
ATOM   4084 C CG1 . VAL C 3  222 ? 6.765   -7.077  -19.293 1.00 45.83 ? 214  VAL I CG1 1 
ATOM   4085 C CG2 . VAL C 3  222 ? 4.989   -6.048  -20.719 1.00 45.31 ? 214  VAL I CG2 1 
ATOM   4086 N N   . PRO C 3  223 ? 3.107   -9.359  -20.967 1.00 43.92 ? 215  PRO I N   1 
ATOM   4087 C CA  . PRO C 3  223 ? 1.788   -9.471  -21.594 1.00 42.65 ? 215  PRO I CA  1 
ATOM   4088 C C   . PRO C 3  223 ? 1.086   -8.113  -21.564 1.00 42.19 ? 215  PRO I C   1 
ATOM   4089 O O   . PRO C 3  223 ? 0.706   -7.620  -20.502 1.00 41.02 ? 215  PRO I O   1 
ATOM   4090 C CB  . PRO C 3  223 ? 1.087   -10.523 -20.737 1.00 43.37 ? 215  PRO I CB  1 
ATOM   4091 C CG  . PRO C 3  223 ? 1.716   -10.337 -19.389 1.00 43.56 ? 215  PRO I CG  1 
ATOM   4092 C CD  . PRO C 3  223 ? 3.175   -10.168 -19.737 1.00 43.75 ? 215  PRO I CD  1 
ATOM   4093 N N   A MET C 3  224 ? 0.923   -7.514  -22.739 0.14 41.31 ? 216  MET I N   1 
ATOM   4094 N N   B MET C 3  224 ? 0.924   -7.515  -22.740 0.35 41.49 ? 216  MET I N   1 
ATOM   4095 C CA  A MET C 3  224 ? 0.286   -6.208  -22.851 0.44 40.74 ? 216  MET I CA  1 
ATOM   4096 C CA  B MET C 3  224 ? 0.278   -6.213  -22.864 0.56 41.12 ? 216  MET I CA  1 
ATOM   4097 C C   A MET C 3  224 ? -1.182  -6.307  -23.253 0.25 40.52 ? 216  MET I C   1 
ATOM   4098 C C   B MET C 3  224 ? -1.190  -6.316  -23.255 0.72 40.71 ? 216  MET I C   1 
ATOM   4099 O O   A MET C 3  224 ? -1.503  -6.724  -24.366 0.13 40.52 ? 216  MET I O   1 
ATOM   4100 O O   B MET C 3  224 ? -1.519  -6.745  -24.362 0.66 40.59 ? 216  MET I O   1 
ATOM   4101 C CB  A MET C 3  224 ? 1.038   -5.354  -23.875 0.12 40.17 ? 216  MET I CB  1 
ATOM   4102 C CB  B MET C 3  224 ? 1.017   -5.362  -23.900 0.50 41.08 ? 216  MET I CB  1 
ATOM   4103 C CG  A MET C 3  224 ? 0.522   -3.932  -24.001 0.46 39.32 ? 216  MET I CG  1 
ATOM   4104 C CG  B MET C 3  224 ? 2.225   -4.623  -23.356 0.54 41.10 ? 216  MET I CG  1 
ATOM   4105 S SD  A MET C 3  224 ? 0.769   -2.980  -22.494 0.33 38.17 ? 216  MET I SD  1 
ATOM   4106 S SD  B MET C 3  224 ? 1.762   -3.104  -22.508 0.67 40.75 ? 216  MET I SD  1 
ATOM   4107 C CE  A MET C 3  224 ? 2.353   -2.213  -22.837 0.76 36.92 ? 216  MET I CE  1 
ATOM   4108 C CE  B MET C 3  224 ? 2.177   -1.895  -23.745 0.10 41.11 ? 216  MET I CE  1 
ATOM   4109 N N   . MET C 3  225 ? -2.070  -5.922  -22.341 1.00 40.41 ? 217  MET I N   1 
ATOM   4110 C CA  . MET C 3  225 ? -3.500  -5.950  -22.612 1.00 39.58 ? 217  MET I CA  1 
ATOM   4111 C C   . MET C 3  225 ? -3.752  -4.706  -23.451 1.00 39.37 ? 217  MET I C   1 
ATOM   4112 O O   . MET C 3  225 ? -2.920  -3.798  -23.486 1.00 38.60 ? 217  MET I O   1 
ATOM   4113 C CB  . MET C 3  225 ? -4.316  -5.841  -21.322 1.00 39.25 ? 217  MET I CB  1 
ATOM   4114 C CG  . MET C 3  225 ? -3.968  -6.846  -20.238 1.00 38.34 ? 217  MET I CG  1 
ATOM   4115 S SD  . MET C 3  225 ? -5.107  -6.692  -18.846 1.00 39.57 ? 217  MET I SD  1 
ATOM   4116 C CE  . MET C 3  225 ? -4.562  -5.130  -18.138 1.00 38.12 ? 217  MET I CE  1 
ATOM   4117 N N   . SER C 3  226 ? -4.892  -4.655  -24.126 1.00 40.39 ? 218  SER I N   1 
ATOM   4118 C CA  . SER C 3  226 ? -5.206  -3.492  -24.940 1.00 40.52 ? 218  SER I CA  1 
ATOM   4119 C C   . SER C 3  226 ? -6.686  -3.404  -25.240 1.00 40.02 ? 218  SER I C   1 
ATOM   4120 O O   . SER C 3  226 ? -7.406  -4.401  -25.201 1.00 39.28 ? 218  SER I O   1 
ATOM   4121 C CB  . SER C 3  226 ? -4.426  -3.528  -26.257 1.00 42.18 ? 218  SER I CB  1 
ATOM   4122 O OG  . SER C 3  226 ? -4.904  -4.557  -27.105 1.00 43.35 ? 218  SER I OG  1 
ATOM   4123 N N   . ARG C 3  227 ? -7.133  -2.191  -25.536 1.00 39.99 ? 219  ARG I N   1 
ATOM   4124 C CA  . ARG C 3  227 ? -8.525  -1.951  -25.859 1.00 39.85 ? 219  ARG I CA  1 
ATOM   4125 C C   . ARG C 3  227 ? -8.718  -0.504  -26.262 1.00 39.99 ? 219  ARG I C   1 
ATOM   4126 O O   . ARG C 3  227 ? -8.445  0.410   -25.482 1.00 37.76 ? 219  ARG I O   1 
ATOM   4127 C CB  . ARG C 3  227 ? -9.424  -2.261  -24.662 1.00 41.39 ? 219  ARG I CB  1 
ATOM   4128 C CG  . ARG C 3  227 ? -10.909 -2.128  -24.969 1.00 43.25 ? 219  ARG I CG  1 
ATOM   4129 C CD  . ARG C 3  227 ? -11.739 -2.302  -23.717 1.00 45.51 ? 219  ARG I CD  1 
ATOM   4130 N NE  . ARG C 3  227 ? -11.583 -1.172  -22.808 1.00 47.50 ? 219  ARG I NE  1 
ATOM   4131 C CZ  . ARG C 3  227 ? -11.886 -1.210  -21.515 1.00 47.67 ? 219  ARG I CZ  1 
ATOM   4132 N NH1 . ARG C 3  227 ? -12.358 -2.326  -20.979 1.00 48.30 ? 219  ARG I NH1 1 
ATOM   4133 N NH2 . ARG C 3  227 ? -11.723 -0.133  -20.760 1.00 47.34 ? 219  ARG I NH2 1 
ATOM   4134 N N   . GLU C 3  228 ? -9.169  -0.297  -27.492 1.00 39.99 ? 220  GLU I N   1 
ATOM   4135 C CA  . GLU C 3  228 ? -9.427  1.049   -27.965 1.00 39.85 ? 220  GLU I CA  1 
ATOM   4136 C C   . GLU C 3  228 ? -10.807 1.394   -27.433 1.00 39.28 ? 220  GLU I C   1 
ATOM   4137 O O   . GLU C 3  228 ? -11.764 0.645   -27.632 1.00 39.89 ? 220  GLU I O   1 
ATOM   4138 C CB  . GLU C 3  228 ? -9.422  1.104   -29.494 1.00 40.85 ? 220  GLU I CB  1 
ATOM   4139 C CG  . GLU C 3  228 ? -9.768  2.477   -30.046 1.00 43.27 ? 220  GLU I CG  1 
ATOM   4140 C CD  . GLU C 3  228 ? -9.659  2.551   -31.553 1.00 43.89 ? 220  GLU I CD  1 
ATOM   4141 O OE1 . GLU C 3  228 ? -9.983  3.615   -32.116 1.00 44.68 ? 220  GLU I OE1 1 
ATOM   4142 O OE2 . GLU C 3  228 ? -9.247  1.549   -32.176 1.00 46.50 ? 220  GLU I OE2 1 
ATOM   4143 N N   . ASP C 3  229 ? -10.903 2.520   -26.740 1.00 38.05 ? 221  ASP I N   1 
ATOM   4144 C CA  . ASP C 3  229 ? -12.169 2.947   -26.169 1.00 37.19 ? 221  ASP I CA  1 
ATOM   4145 C C   . ASP C 3  229 ? -11.973 4.325   -25.562 1.00 34.55 ? 221  ASP I C   1 
ATOM   4146 O O   . ASP C 3  229 ? -10.893 4.903   -25.667 1.00 34.52 ? 221  ASP I O   1 
ATOM   4147 C CB  . ASP C 3  229 ? -12.611 1.942   -25.099 1.00 39.57 ? 221  ASP I CB  1 
ATOM   4148 C CG  . ASP C 3  229 ? -13.968 2.268   -24.512 1.00 41.78 ? 221  ASP I CG  1 
ATOM   4149 O OD1 . ASP C 3  229 ? -14.825 2.789   -25.255 1.00 44.04 ? 221  ASP I OD1 1 
ATOM   4150 O OD2 . ASP C 3  229 ? -14.183 1.988   -23.314 1.00 42.57 ? 221  ASP I OD2 1 
ATOM   4151 N N   . GLN C 3  230 ? -13.020 4.863   -24.949 1.00 34.02 ? 222  GLN I N   1 
ATOM   4152 C CA  . GLN C 3  230 ? -12.918 6.167   -24.316 1.00 33.45 ? 222  GLN I CA  1 
ATOM   4153 C C   . GLN C 3  230 ? -12.541 5.978   -22.857 1.00 32.24 ? 222  GLN I C   1 
ATOM   4154 O O   . GLN C 3  230 ? -13.090 5.112   -22.173 1.00 32.73 ? 222  GLN I O   1 
ATOM   4155 C CB  . GLN C 3  230 ? -14.237 6.930   -24.412 1.00 34.66 ? 222  GLN I CB  1 
ATOM   4156 C CG  . GLN C 3  230 ? -14.538 7.456   -25.800 1.00 37.35 ? 222  GLN I CG  1 
ATOM   4157 C CD  . GLN C 3  230 ? -15.217 8.806   -25.755 1.00 40.04 ? 222  GLN I CD  1 
ATOM   4158 O OE1 . GLN C 3  230 ? -16.316 8.942   -25.216 1.00 41.65 ? 222  GLN I OE1 1 
ATOM   4159 N NE2 . GLN C 3  230 ? -14.560 9.818   -26.315 1.00 40.04 ? 222  GLN I NE2 1 
ATOM   4160 N N   . TYR C 3  231 ? -11.602 6.793   -22.391 1.00 31.07 ? 223  TYR I N   1 
ATOM   4161 C CA  . TYR C 3  231 ? -11.128 6.724   -21.012 1.00 29.40 ? 223  TYR I CA  1 
ATOM   4162 C C   . TYR C 3  231 ? -10.997 8.118   -20.420 1.00 29.01 ? 223  TYR I C   1 
ATOM   4163 O O   . TYR C 3  231 ? -10.762 9.085   -21.142 1.00 27.77 ? 223  TYR I O   1 
ATOM   4164 C CB  . TYR C 3  231 ? -9.738  6.085   -20.957 1.00 28.79 ? 223  TYR I CB  1 
ATOM   4165 C CG  . TYR C 3  231 ? -9.647  4.672   -21.475 1.00 28.51 ? 223  TYR I CG  1 
ATOM   4166 C CD1 . TYR C 3  231 ? -9.944  3.588   -20.652 1.00 28.06 ? 223  TYR I CD1 1 
ATOM   4167 C CD2 . TYR C 3  231 ? -9.226  4.415   -22.780 1.00 27.84 ? 223  TYR I CD2 1 
ATOM   4168 C CE1 . TYR C 3  231 ? -9.819  2.279   -21.114 1.00 29.28 ? 223  TYR I CE1 1 
ATOM   4169 C CE2 . TYR C 3  231 ? -9.100  3.112   -23.251 1.00 27.70 ? 223  TYR I CE2 1 
ATOM   4170 C CZ  . TYR C 3  231 ? -9.397  2.051   -22.413 1.00 28.90 ? 223  TYR I CZ  1 
ATOM   4171 O OH  . TYR C 3  231 ? -9.263  0.763   -22.868 1.00 31.76 ? 223  TYR I OH  1 
ATOM   4172 N N   . HIS C 3  232 ? -11.145 8.218   -19.102 1.00 28.46 ? 224  HIS I N   1 
ATOM   4173 C CA  . HIS C 3  232 ? -10.953 9.495   -18.439 1.00 29.81 ? 224  HIS I CA  1 
ATOM   4174 C C   . HIS C 3  232 ? -9.464  9.723   -18.660 1.00 29.45 ? 224  HIS I C   1 
ATOM   4175 O O   . HIS C 3  232 ? -8.637  8.899   -18.263 1.00 28.56 ? 224  HIS I O   1 
ATOM   4176 C CB  . HIS C 3  232 ? -11.275 9.376   -16.949 1.00 32.90 ? 224  HIS I CB  1 
ATOM   4177 C CG  . HIS C 3  232 ? -12.740 9.435   -16.647 1.00 37.20 ? 224  HIS I CG  1 
ATOM   4178 N ND1 . HIS C 3  232 ? -13.286 8.911   -15.495 1.00 39.47 ? 224  HIS I ND1 1 
ATOM   4179 C CD2 . HIS C 3  232 ? -13.771 9.971   -17.341 1.00 39.03 ? 224  HIS I CD2 1 
ATOM   4180 C CE1 . HIS C 3  232 ? -14.590 9.120   -15.493 1.00 40.05 ? 224  HIS I CE1 1 
ATOM   4181 N NE2 . HIS C 3  232 ? -14.911 9.761   -16.603 1.00 40.48 ? 224  HIS I NE2 1 
ATOM   4182 N N   . TYR C 3  233 ? -9.123  10.826  -19.310 1.00 28.92 ? 225  TYR I N   1 
ATOM   4183 C CA  . TYR C 3  233 ? -7.733  11.112  -19.629 1.00 30.21 ? 225  TYR I CA  1 
ATOM   4184 C C   . TYR C 3  233 ? -7.349  12.542  -19.296 1.00 31.73 ? 225  TYR I C   1 
ATOM   4185 O O   . TYR C 3  233 ? -8.198  13.431  -19.272 1.00 31.59 ? 225  TYR I O   1 
ATOM   4186 C CB  . TYR C 3  233 ? -7.501  10.841  -21.119 1.00 29.16 ? 225  TYR I CB  1 
ATOM   4187 C CG  . TYR C 3  233 ? -6.141  11.245  -21.642 1.00 28.78 ? 225  TYR I CG  1 
ATOM   4188 C CD1 . TYR C 3  233 ? -5.034  10.412  -21.488 1.00 27.51 ? 225  TYR I CD1 1 
ATOM   4189 C CD2 . TYR C 3  233 ? -5.963  12.466  -22.289 1.00 28.58 ? 225  TYR I CD2 1 
ATOM   4190 C CE1 . TYR C 3  233 ? -3.779  10.785  -21.971 1.00 28.48 ? 225  TYR I CE1 1 
ATOM   4191 C CE2 . TYR C 3  233 ? -4.714  12.851  -22.775 1.00 30.22 ? 225  TYR I CE2 1 
ATOM   4192 C CZ  . TYR C 3  233 ? -3.628  12.006  -22.614 1.00 28.97 ? 225  TYR I CZ  1 
ATOM   4193 O OH  . TYR C 3  233 ? -2.397  12.384  -23.099 1.00 28.90 ? 225  TYR I OH  1 
ATOM   4194 N N   A LEU C 3  234 ? -6.064  12.761  -19.033 0.36 32.50 ? 226  LEU I N   1 
ATOM   4195 N N   B LEU C 3  234 ? -6.063  12.753  -19.043 0.64 32.30 ? 226  LEU I N   1 
ATOM   4196 C CA  A LEU C 3  234 ? -5.569  14.090  -18.695 0.20 33.87 ? 226  LEU I CA  1 
ATOM   4197 C CA  B LEU C 3  234 ? -5.559  14.079  -18.725 0.80 33.90 ? 226  LEU I CA  1 
ATOM   4198 C C   A LEU C 3  234 ? -4.072  14.210  -18.968 0.18 34.69 ? 226  LEU I C   1 
ATOM   4199 C C   B LEU C 3  234 ? -4.074  14.182  -19.031 0.67 34.80 ? 226  LEU I C   1 
ATOM   4200 O O   A LEU C 3  234 ? -3.296  13.315  -18.634 0.13 34.71 ? 226  LEU I O   1 
ATOM   4201 O O   B LEU C 3  234 ? -3.310  13.247  -18.787 0.87 34.81 ? 226  LEU I O   1 
ATOM   4202 C CB  A LEU C 3  234 ? -5.865  14.392  -17.219 0.12 34.07 ? 226  LEU I CB  1 
ATOM   4203 C CB  B LEU C 3  234 ? -5.792  14.400  -17.246 0.88 34.27 ? 226  LEU I CB  1 
ATOM   4204 C CG  A LEU C 3  234 ? -5.469  15.745  -16.614 0.10 34.42 ? 226  LEU I CG  1 
ATOM   4205 C CG  B LEU C 3  234 ? -5.299  15.777  -16.791 0.47 34.81 ? 226  LEU I CG  1 
ATOM   4206 C CD1 A LEU C 3  234 ? -3.974  15.787  -16.344 0.50 35.26 ? 226  LEU I CD1 1 
ATOM   4207 C CD1 B LEU C 3  234 ? -6.102  16.863  -17.493 0.50 35.22 ? 226  LEU I CD1 1 
ATOM   4208 C CD2 A LEU C 3  234 ? -5.895  16.869  -17.546 0.10 34.50 ? 226  LEU I CD2 1 
ATOM   4209 C CD2 B LEU C 3  234 ? -5.438  15.901  -15.283 0.75 35.10 ? 226  LEU I CD2 1 
ATOM   4210 N N   . LEU C 3  235 ? -3.677  15.323  -19.579 1.00 35.73 ? 227  LEU I N   1 
ATOM   4211 C CA  . LEU C 3  235 ? -2.279  15.574  -19.901 1.00 36.74 ? 227  LEU I CA  1 
ATOM   4212 C C   . LEU C 3  235 ? -1.775  16.663  -18.966 1.00 38.79 ? 227  LEU I C   1 
ATOM   4213 O O   . LEU C 3  235 ? -2.006  17.850  -19.200 1.00 39.14 ? 227  LEU I O   1 
ATOM   4214 C CB  . LEU C 3  235 ? -2.131  16.035  -21.353 1.00 37.23 ? 227  LEU I CB  1 
ATOM   4215 C CG  . LEU C 3  235 ? -0.750  16.557  -21.765 1.00 38.17 ? 227  LEU I CG  1 
ATOM   4216 C CD1 . LEU C 3  235 ? 0.322   15.511  -21.478 1.00 38.41 ? 227  LEU I CD1 1 
ATOM   4217 C CD2 . LEU C 3  235 ? -0.772  16.913  -23.244 1.00 37.95 ? 227  LEU I CD2 1 
ATOM   4218 N N   . ASP C 3  236 ? -1.100  16.255  -17.898 1.00 39.55 ? 228  ASP I N   1 
ATOM   4219 C CA  . ASP C 3  236 ? -0.567  17.203  -16.934 1.00 40.84 ? 228  ASP I CA  1 
ATOM   4220 C C   . ASP C 3  236 ? 0.729   17.798  -17.478 1.00 41.54 ? 228  ASP I C   1 
ATOM   4221 O O   . ASP C 3  236 ? 1.786   17.171  -17.423 1.00 41.48 ? 228  ASP I O   1 
ATOM   4222 C CB  . ASP C 3  236 ? -0.318  16.501  -15.596 1.00 41.01 ? 228  ASP I CB  1 
ATOM   4223 C CG  . ASP C 3  236 ? 0.089   17.464  -14.498 1.00 42.01 ? 228  ASP I CG  1 
ATOM   4224 O OD1 . ASP C 3  236 ? 0.090   17.051  -13.320 1.00 41.74 ? 228  ASP I OD1 1 
ATOM   4225 O OD2 . ASP C 3  236 ? 0.412   18.629  -14.811 1.00 42.18 ? 228  ASP I OD2 1 
ATOM   4226 N N   . ARG C 3  237 ? 0.632   19.010  -18.015 1.00 42.54 ? 229  ARG I N   1 
ATOM   4227 C CA  . ARG C 3  237 ? 1.786   19.697  -18.581 1.00 43.21 ? 229  ARG I CA  1 
ATOM   4228 C C   . ARG C 3  237 ? 2.741   20.165  -17.491 1.00 43.81 ? 229  ARG I C   1 
ATOM   4229 O O   . ARG C 3  237 ? 3.946   20.279  -17.715 1.00 44.11 ? 229  ARG I O   1 
ATOM   4230 C CB  . ARG C 3  237 ? 1.328   20.897  -19.413 1.00 43.26 ? 229  ARG I CB  1 
ATOM   4231 N N   . ASN C 3  238 ? 2.195   20.434  -16.310 1.00 44.20 ? 230  ASN I N   1 
ATOM   4232 C CA  . ASN C 3  238 ? 2.997   20.894  -15.184 1.00 45.25 ? 230  ASN I CA  1 
ATOM   4233 C C   . ASN C 3  238 ? 4.020   19.840  -14.766 1.00 44.37 ? 230  ASN I C   1 
ATOM   4234 O O   . ASN C 3  238 ? 5.218   20.117  -14.713 1.00 45.90 ? 230  ASN I O   1 
ATOM   4235 C CB  . ASN C 3  238 ? 2.089   21.235  -13.999 1.00 46.68 ? 230  ASN I CB  1 
ATOM   4236 C CG  . ASN C 3  238 ? 2.856   21.803  -12.823 1.00 48.61 ? 230  ASN I CG  1 
ATOM   4237 O OD1 . ASN C 3  238 ? 3.510   22.841  -12.937 1.00 49.73 ? 230  ASN I OD1 1 
ATOM   4238 N ND2 . ASN C 3  238 ? 2.782   21.125  -11.684 1.00 49.74 ? 230  ASN I ND2 1 
ATOM   4239 N N   . LEU C 3  239 ? 3.543   18.633  -14.475 1.00 42.71 ? 231  LEU I N   1 
ATOM   4240 C CA  . LEU C 3  239 ? 4.423   17.543  -14.064 1.00 40.91 ? 231  LEU I CA  1 
ATOM   4241 C C   . LEU C 3  239 ? 4.947   16.769  -15.267 1.00 39.72 ? 231  LEU I C   1 
ATOM   4242 O O   . LEU C 3  239 ? 5.875   15.968  -15.147 1.00 39.34 ? 231  LEU I O   1 
ATOM   4243 C CB  . LEU C 3  239 ? 3.681   16.588  -13.127 1.00 40.92 ? 231  LEU I CB  1 
ATOM   4244 C CG  . LEU C 3  239 ? 3.191   17.170  -11.799 1.00 41.58 ? 231  LEU I CG  1 
ATOM   4245 C CD1 . LEU C 3  239 ? 2.466   16.090  -11.010 1.00 41.04 ? 231  LEU I CD1 1 
ATOM   4246 C CD2 . LEU C 3  239 ? 4.370   17.712  -11.005 1.00 41.61 ? 231  LEU I CD2 1 
ATOM   4247 N N   . SER C 3  240 ? 4.342   17.015  -16.425 1.00 37.19 ? 232  SER I N   1 
ATOM   4248 C CA  . SER C 3  240 ? 4.729   16.358  -17.669 1.00 35.29 ? 232  SER I CA  1 
ATOM   4249 C C   . SER C 3  240 ? 4.450   14.856  -17.648 1.00 33.86 ? 232  SER I C   1 
ATOM   4250 O O   . SER C 3  240 ? 5.366   14.037  -17.740 1.00 33.60 ? 232  SER I O   1 
ATOM   4251 C CB  . SER C 3  240 ? 6.211   16.607  -17.959 1.00 35.26 ? 232  SER I CB  1 
ATOM   4252 O OG  . SER C 3  240 ? 6.565   16.106  -19.235 1.00 36.14 ? 232  SER I OG  1 
ATOM   4253 N N   . CYS C 3  241 ? 3.175   14.500  -17.533 1.00 31.73 ? 233  CYS I N   1 
ATOM   4254 C CA  . CYS C 3  241 ? 2.776   13.099  -17.505 1.00 30.76 ? 233  CYS I CA  1 
ATOM   4255 C C   . CYS C 3  241 ? 1.349   12.934  -18.003 1.00 30.27 ? 233  CYS I C   1 
ATOM   4256 O O   . CYS C 3  241 ? 0.547   13.864  -17.933 1.00 30.69 ? 233  CYS I O   1 
ATOM   4257 C CB  . CYS C 3  241 ? 2.887   12.543  -16.079 1.00 29.07 ? 233  CYS I CB  1 
ATOM   4258 S SG  . CYS C 3  241 ? 1.867   13.402  -14.849 1.00 28.87 ? 233  CYS I SG  1 
ATOM   4259 N N   . ARG C 3  242 ? 1.046   11.744  -18.512 1.00 28.87 ? 234  ARG I N   1 
ATOM   4260 C CA  . ARG C 3  242 ? -0.287  11.430  -19.008 1.00 29.30 ? 234  ARG I CA  1 
ATOM   4261 C C   . ARG C 3  242 ? -0.975  10.547  -17.969 1.00 28.23 ? 234  ARG I C   1 
ATOM   4262 O O   . ARG C 3  242 ? -0.399  9.570   -17.486 1.00 27.23 ? 234  ARG I O   1 
ATOM   4263 C CB  . ARG C 3  242 ? -0.186  10.711  -20.358 1.00 31.37 ? 234  ARG I CB  1 
ATOM   4264 C CG  . ARG C 3  242 ? 0.487   11.565  -21.437 1.00 34.26 ? 234  ARG I CG  1 
ATOM   4265 C CD  . ARG C 3  242 ? 0.863   10.760  -22.672 1.00 37.94 ? 234  ARG I CD  1 
ATOM   4266 N NE  . ARG C 3  242 ? -0.297  10.312  -23.436 1.00 41.13 ? 234  ARG I NE  1 
ATOM   4267 C CZ  . ARG C 3  242 ? -0.225  9.532   -24.511 1.00 42.70 ? 234  ARG I CZ  1 
ATOM   4268 N NH1 . ARG C 3  242 ? 0.955   9.111   -24.949 1.00 43.67 ? 234  ARG I NH1 1 
ATOM   4269 N NH2 . ARG C 3  242 ? -1.333  9.167   -25.146 1.00 42.72 ? 234  ARG I NH2 1 
ATOM   4270 N N   . VAL C 3  243 ? -2.206  10.902  -17.624 1.00 26.46 ? 235  VAL I N   1 
ATOM   4271 C CA  . VAL C 3  243 ? -2.960  10.164  -16.620 1.00 25.04 ? 235  VAL I CA  1 
ATOM   4272 C C   . VAL C 3  243 ? -4.236  9.574   -17.195 1.00 24.97 ? 235  VAL I C   1 
ATOM   4273 O O   . VAL C 3  243 ? -5.039  10.286  -17.801 1.00 23.98 ? 235  VAL I O   1 
ATOM   4274 C CB  . VAL C 3  243 ? -3.343  11.086  -15.448 1.00 25.23 ? 235  VAL I CB  1 
ATOM   4275 C CG1 . VAL C 3  243 ? -3.949  10.271  -14.320 1.00 24.86 ? 235  VAL I CG1 1 
ATOM   4276 C CG2 . VAL C 3  243 ? -2.123  11.848  -14.970 1.00 26.80 ? 235  VAL I CG2 1 
ATOM   4277 N N   . VAL C 3  244 ? -4.419  8.271   -17.007 1.00 23.51 ? 236  VAL I N   1 
ATOM   4278 C CA  . VAL C 3  244 ? -5.616  7.601   -17.496 1.00 24.31 ? 236  VAL I CA  1 
ATOM   4279 C C   . VAL C 3  244 ? -6.338  6.909   -16.348 1.00 24.59 ? 236  VAL I C   1 
ATOM   4280 O O   . VAL C 3  244 ? -5.713  6.299   -15.480 1.00 22.64 ? 236  VAL I O   1 
ATOM   4281 C CB  . VAL C 3  244 ? -5.283  6.552   -18.583 1.00 25.34 ? 236  VAL I CB  1 
ATOM   4282 C CG1 . VAL C 3  244 ? -4.414  5.443   -18.002 1.00 26.36 ? 236  VAL I CG1 1 
ATOM   4283 C CG2 . VAL C 3  244 ? -6.572  5.971   -19.151 1.00 26.32 ? 236  VAL I CG2 1 
ATOM   4284 N N   . GLY C 3  245 ? -7.660  7.025   -16.336 1.00 24.13 ? 237  GLY I N   1 
ATOM   4285 C CA  . GLY C 3  245 ? -8.441  6.389   -15.296 1.00 24.20 ? 237  GLY I CA  1 
ATOM   4286 C C   . GLY C 3  245 ? -9.168  5.174   -15.842 1.00 26.11 ? 237  GLY I C   1 
ATOM   4287 O O   . GLY C 3  245 ? -9.834  5.251   -16.874 1.00 26.17 ? 237  GLY I O   1 
ATOM   4288 N N   . VAL C 3  246 ? -9.022  4.043   -15.160 1.00 26.68 ? 238  VAL I N   1 
ATOM   4289 C CA  . VAL C 3  246 ? -9.681  2.806   -15.562 1.00 27.47 ? 238  VAL I CA  1 
ATOM   4290 C C   . VAL C 3  246 ? -10.497 2.365   -14.348 1.00 29.82 ? 238  VAL I C   1 
ATOM   4291 O O   . VAL C 3  246 ? -9.950  1.839   -13.378 1.00 28.52 ? 238  VAL I O   1 
ATOM   4292 C CB  . VAL C 3  246 ? -8.653  1.712   -15.927 1.00 27.65 ? 238  VAL I CB  1 
ATOM   4293 C CG1 . VAL C 3  246 ? -9.365  0.509   -16.530 1.00 28.65 ? 238  VAL I CG1 1 
ATOM   4294 C CG2 . VAL C 3  246 ? -7.621  2.269   -16.901 1.00 28.13 ? 238  VAL I CG2 1 
ATOM   4295 N N   . PRO C 3  247 ? -11.822 2.581   -14.388 1.00 30.26 ? 239  PRO I N   1 
ATOM   4296 C CA  . PRO C 3  247 ? -12.728 2.222   -13.294 1.00 31.59 ? 239  PRO I CA  1 
ATOM   4297 C C   . PRO C 3  247 ? -12.957 0.736   -13.036 1.00 32.30 ? 239  PRO I C   1 
ATOM   4298 O O   . PRO C 3  247 ? -12.968 -0.081  -13.958 1.00 32.46 ? 239  PRO I O   1 
ATOM   4299 C CB  . PRO C 3  247 ? -14.018 2.934   -13.681 1.00 32.18 ? 239  PRO I CB  1 
ATOM   4300 C CG  . PRO C 3  247 ? -14.005 2.806   -15.174 1.00 31.64 ? 239  PRO I CG  1 
ATOM   4301 C CD  . PRO C 3  247 ? -12.574 3.176   -15.510 1.00 31.42 ? 239  PRO I CD  1 
ATOM   4302 N N   . TYR C 3  248 ? -13.133 0.403   -11.761 1.00 32.95 ? 240  TYR I N   1 
ATOM   4303 C CA  . TYR C 3  248 ? -13.411 -0.961  -11.335 1.00 34.71 ? 240  TYR I CA  1 
ATOM   4304 C C   . TYR C 3  248 ? -14.923 -1.032  -11.169 1.00 37.05 ? 240  TYR I C   1 
ATOM   4305 O O   . TYR C 3  248 ? -15.592 0.000   -11.161 1.00 37.34 ? 240  TYR I O   1 
ATOM   4306 C CB  . TYR C 3  248 ? -12.747 -1.257  -9.985  1.00 32.96 ? 240  TYR I CB  1 
ATOM   4307 C CG  . TYR C 3  248 ? -11.292 -1.649  -10.065 1.00 30.59 ? 240  TYR I CG  1 
ATOM   4308 C CD1 . TYR C 3  248 ? -10.906 -2.850  -10.656 1.00 30.02 ? 240  TYR I CD1 1 
ATOM   4309 C CD2 . TYR C 3  248 ? -10.299 -0.827  -9.535  1.00 31.15 ? 240  TYR I CD2 1 
ATOM   4310 C CE1 . TYR C 3  248 ? -9.566  -3.227  -10.717 1.00 29.60 ? 240  TYR I CE1 1 
ATOM   4311 C CE2 . TYR C 3  248 ? -8.955  -1.193  -9.592  1.00 28.79 ? 240  TYR I CE2 1 
ATOM   4312 C CZ  . TYR C 3  248 ? -8.596  -2.393  -10.182 1.00 29.68 ? 240  TYR I CZ  1 
ATOM   4313 O OH  . TYR C 3  248 ? -7.271  -2.762  -10.237 1.00 29.13 ? 240  TYR I OH  1 
ATOM   4314 N N   . GLN C 3  249 ? -15.460 -2.239  -11.035 1.00 39.99 ? 241  GLN I N   1 
ATOM   4315 C CA  . GLN C 3  249 ? -16.896 -2.398  -10.852 1.00 43.08 ? 241  GLN I CA  1 
ATOM   4316 C C   . GLN C 3  249 ? -17.295 -1.733  -9.539  1.00 44.31 ? 241  GLN I C   1 
ATOM   4317 O O   . GLN C 3  249 ? -17.123 -2.312  -8.469  1.00 46.17 ? 241  GLN I O   1 
ATOM   4318 C CB  . GLN C 3  249 ? -17.267 -3.883  -10.817 1.00 43.56 ? 241  GLN I CB  1 
ATOM   4319 N N   . GLY C 3  250 ? -17.815 -0.513  -9.623  1.00 45.59 ? 242  GLY I N   1 
ATOM   4320 C CA  . GLY C 3  250 ? -18.224 0.196   -8.423  1.00 46.10 ? 242  GLY I CA  1 
ATOM   4321 C C   . GLY C 3  250 ? -17.785 1.648   -8.403  1.00 46.39 ? 242  GLY I C   1 
ATOM   4322 O O   . GLY C 3  250 ? -17.935 2.364   -9.394  1.00 47.64 ? 242  GLY I O   1 
ATOM   4323 N N   . ASN C 3  251 ? -17.244 2.088   -7.271  1.00 45.79 ? 243  ASN I N   1 
ATOM   4324 C CA  . ASN C 3  251 ? -16.781 3.465   -7.129  1.00 43.78 ? 243  ASN I CA  1 
ATOM   4325 C C   . ASN C 3  251 ? -15.257 3.515   -7.088  1.00 42.15 ? 243  ASN I C   1 
ATOM   4326 O O   . ASN C 3  251 ? -14.662 4.589   -6.998  1.00 42.10 ? 243  ASN I O   1 
ATOM   4327 C CB  . ASN C 3  251 ? -17.352 4.088   -5.853  1.00 44.80 ? 243  ASN I CB  1 
ATOM   4328 N N   . ALA C 3  252 ? -14.632 2.345   -7.148  1.00 40.07 ? 244  ALA I N   1 
ATOM   4329 C CA  . ALA C 3  252 ? -13.180 2.254   -7.124  1.00 37.35 ? 244  ALA I CA  1 
ATOM   4330 C C   . ALA C 3  252 ? -12.639 2.397   -8.539  1.00 35.16 ? 244  ALA I C   1 
ATOM   4331 O O   . ALA C 3  252 ? -13.224 1.888   -9.493  1.00 33.91 ? 244  ALA I O   1 
ATOM   4332 C CB  . ALA C 3  252 ? -12.747 0.922   -6.534  1.00 38.42 ? 244  ALA I CB  1 
ATOM   4333 N N   . THR C 3  253 ? -11.520 3.096   -8.673  1.00 32.89 ? 245  THR I N   1 
ATOM   4334 C CA  . THR C 3  253 ? -10.916 3.289   -9.981  1.00 31.20 ? 245  THR I CA  1 
ATOM   4335 C C   . THR C 3  253 ? -9.402  3.233   -9.889  1.00 29.85 ? 245  THR I C   1 
ATOM   4336 O O   . THR C 3  253 ? -8.815  3.594   -8.868  1.00 28.63 ? 245  THR I O   1 
ATOM   4337 C CB  . THR C 3  253 ? -11.316 4.649   -10.594 1.00 32.19 ? 245  THR I CB  1 
ATOM   4338 O OG1 . THR C 3  253 ? -10.779 4.752   -11.921 1.00 33.56 ? 245  THR I OG1 1 
ATOM   4339 C CG2 . THR C 3  253 ? -10.775 5.790   -9.754  1.00 31.80 ? 245  THR I CG2 1 
ATOM   4340 N N   . ALA C 3  254 ? -8.777  2.765   -10.960 1.00 28.07 ? 246  ALA I N   1 
ATOM   4341 C CA  . ALA C 3  254 ? -7.330  2.682   -11.018 1.00 26.76 ? 246  ALA I CA  1 
ATOM   4342 C C   . ALA C 3  254 ? -6.838  3.836   -11.868 1.00 26.14 ? 246  ALA I C   1 
ATOM   4343 O O   . ALA C 3  254 ? -7.435  4.157   -12.897 1.00 26.98 ? 246  ALA I O   1 
ATOM   4344 C CB  . ALA C 3  254 ? -6.897  1.360   -11.637 1.00 26.22 ? 246  ALA I CB  1 
ATOM   4345 N N   . LEU C 3  255 ? -5.761  4.472   -11.427 1.00 24.10 ? 247  LEU I N   1 
ATOM   4346 C CA  . LEU C 3  255 ? -5.179  5.572   -12.173 1.00 23.49 ? 247  LEU I CA  1 
ATOM   4347 C C   . LEU C 3  255 ? -3.783  5.140   -12.582 1.00 23.10 ? 247  LEU I C   1 
ATOM   4348 O O   . LEU C 3  255 ? -3.005  4.670   -11.749 1.00 20.37 ? 247  LEU I O   1 
ATOM   4349 C CB  . LEU C 3  255 ? -5.080  6.829   -11.309 1.00 24.44 ? 247  LEU I CB  1 
ATOM   4350 C CG  . LEU C 3  255 ? -6.355  7.399   -10.688 1.00 25.75 ? 247  LEU I CG  1 
ATOM   4351 C CD1 . LEU C 3  255 ? -6.003  8.676   -9.937  1.00 28.31 ? 247  LEU I CD1 1 
ATOM   4352 C CD2 . LEU C 3  255 ? -7.390  7.685   -11.766 1.00 26.60 ? 247  LEU I CD2 1 
ATOM   4353 N N   . PHE C 3  256 ? -3.476  5.277   -13.867 1.00 22.57 ? 248  PHE I N   1 
ATOM   4354 C CA  . PHE C 3  256 ? -2.158  4.925   -14.370 1.00 22.65 ? 248  PHE I CA  1 
ATOM   4355 C C   . PHE C 3  256 ? -1.517  6.193   -14.920 1.00 22.98 ? 248  PHE I C   1 
ATOM   4356 O O   . PHE C 3  256 ? -2.090  6.877   -15.770 1.00 22.37 ? 248  PHE I O   1 
ATOM   4357 C CB  . PHE C 3  256 ? -2.268  3.844   -15.444 1.00 23.98 ? 248  PHE I CB  1 
ATOM   4358 C CG  . PHE C 3  256 ? -2.814  2.542   -14.928 1.00 24.50 ? 248  PHE I CG  1 
ATOM   4359 C CD1 . PHE C 3  256 ? -4.138  2.185   -15.156 1.00 24.76 ? 248  PHE I CD1 1 
ATOM   4360 C CD2 . PHE C 3  256 ? -2.010  1.685   -14.179 1.00 23.88 ? 248  PHE I CD2 1 
ATOM   4361 C CE1 . PHE C 3  256 ? -4.658  0.993   -14.648 1.00 26.07 ? 248  PHE I CE1 1 
ATOM   4362 C CE2 . PHE C 3  256 ? -2.521  0.491   -13.666 1.00 24.66 ? 248  PHE I CE2 1 
ATOM   4363 C CZ  . PHE C 3  256 ? -3.848  0.146   -13.902 1.00 24.99 ? 248  PHE I CZ  1 
ATOM   4364 N N   . ILE C 3  257 ? -0.334  6.509   -14.406 1.00 22.42 ? 249  ILE I N   1 
ATOM   4365 C CA  . ILE C 3  257 ? 0.382   7.711   -14.799 1.00 23.59 ? 249  ILE I CA  1 
ATOM   4366 C C   . ILE C 3  257 ? 1.673   7.385   -15.537 1.00 24.06 ? 249  ILE I C   1 
ATOM   4367 O O   . ILE C 3  257 ? 2.564   6.732   -14.995 1.00 22.50 ? 249  ILE I O   1 
ATOM   4368 C CB  . ILE C 3  257 ? 0.732   8.577   -13.563 1.00 24.35 ? 249  ILE I CB  1 
ATOM   4369 C CG1 . ILE C 3  257 ? -0.536  8.918   -12.772 1.00 25.96 ? 249  ILE I CG1 1 
ATOM   4370 C CG2 . ILE C 3  257 ? 1.429   9.854   -14.001 1.00 25.28 ? 249  ILE I CG2 1 
ATOM   4371 C CD1 . ILE C 3  257 ? -1.001  7.813   -11.839 1.00 28.58 ? 249  ILE I CD1 1 
ATOM   4372 N N   . LEU C 3  258 ? 1.767   7.847   -16.779 1.00 23.74 ? 250  LEU I N   1 
ATOM   4373 C CA  . LEU C 3  258 ? 2.953   7.615   -17.593 1.00 24.77 ? 250  LEU I CA  1 
ATOM   4374 C C   . LEU C 3  258 ? 3.740   8.908   -17.738 1.00 25.54 ? 250  LEU I C   1 
ATOM   4375 O O   . LEU C 3  258 ? 3.377   9.779   -18.528 1.00 25.64 ? 250  LEU I O   1 
ATOM   4376 C CB  . LEU C 3  258 ? 2.559   7.109   -18.983 1.00 23.91 ? 250  LEU I CB  1 
ATOM   4377 C CG  . LEU C 3  258 ? 3.711   6.754   -19.930 1.00 25.03 ? 250  LEU I CG  1 
ATOM   4378 C CD1 . LEU C 3  258 ? 4.425   5.514   -19.423 1.00 23.19 ? 250  LEU I CD1 1 
ATOM   4379 C CD2 . LEU C 3  258 ? 3.168   6.505   -21.328 1.00 23.40 ? 250  LEU I CD2 1 
ATOM   4380 N N   . PRO C 3  259 ? 4.830   9.057   -16.973 1.00 26.93 ? 251  PRO I N   1 
ATOM   4381 C CA  . PRO C 3  259 ? 5.618   10.288  -17.088 1.00 26.94 ? 251  PRO I CA  1 
ATOM   4382 C C   . PRO C 3  259 ? 6.225   10.387  -18.488 1.00 28.29 ? 251  PRO I C   1 
ATOM   4383 O O   . PRO C 3  259 ? 6.382   9.376   -19.176 1.00 26.78 ? 251  PRO I O   1 
ATOM   4384 C CB  . PRO C 3  259 ? 6.700   10.111  -16.022 1.00 27.72 ? 251  PRO I CB  1 
ATOM   4385 C CG  . PRO C 3  259 ? 6.061   9.182   -15.021 1.00 26.98 ? 251  PRO I CG  1 
ATOM   4386 C CD  . PRO C 3  259 ? 5.360   8.188   -15.908 1.00 26.14 ? 251  PRO I CD  1 
ATOM   4387 N N   . SER C 3  260 ? 6.554   11.599  -18.915 1.00 30.39 ? 252  SER I N   1 
ATOM   4388 C CA  . SER C 3  260 ? 7.179   11.765  -20.219 1.00 32.25 ? 252  SER I CA  1 
ATOM   4389 C C   . SER C 3  260 ? 8.626   11.330  -20.017 1.00 34.55 ? 252  SER I C   1 
ATOM   4390 O O   . SER C 3  260 ? 9.095   11.244  -18.881 1.00 33.48 ? 252  SER I O   1 
ATOM   4391 C CB  . SER C 3  260 ? 7.118   13.227  -20.670 1.00 31.99 ? 252  SER I CB  1 
ATOM   4392 O OG  . SER C 3  260 ? 7.839   14.068  -19.790 1.00 33.98 ? 252  SER I OG  1 
ATOM   4393 N N   . GLU C 3  261 ? 9.327   11.046  -21.110 1.00 35.75 ? 253  GLU I N   1 
ATOM   4394 C CA  . GLU C 3  261 ? 10.717  10.603  -21.040 1.00 37.50 ? 253  GLU I CA  1 
ATOM   4395 C C   . GLU C 3  261 ? 11.556  11.356  -20.012 1.00 37.65 ? 253  GLU I C   1 
ATOM   4396 O O   . GLU C 3  261 ? 11.611  12.587  -20.018 1.00 36.73 ? 253  GLU I O   1 
ATOM   4397 C CB  . GLU C 3  261 ? 11.370  10.728  -22.418 1.00 39.69 ? 253  GLU I CB  1 
ATOM   4398 C CG  . GLU C 3  261 ? 10.788  9.794   -23.470 1.00 42.78 ? 253  GLU I CG  1 
ATOM   4399 C CD  . GLU C 3  261 ? 11.127  8.338   -23.213 1.00 45.29 ? 253  GLU I CD  1 
ATOM   4400 O OE1 . GLU C 3  261 ? 10.702  7.479   -24.014 1.00 47.62 ? 253  GLU I OE1 1 
ATOM   4401 O OE2 . GLU C 3  261 ? 11.821  8.051   -22.214 1.00 46.97 ? 253  GLU I OE2 1 
ATOM   4402 N N   . GLY C 3  262 ? 12.200  10.598  -19.126 1.00 37.92 ? 254  GLY I N   1 
ATOM   4403 C CA  . GLY C 3  262 ? 13.055  11.174  -18.101 1.00 37.87 ? 254  GLY I CA  1 
ATOM   4404 C C   . GLY C 3  262 ? 12.402  12.071  -17.066 1.00 38.69 ? 254  GLY I C   1 
ATOM   4405 O O   . GLY C 3  262 ? 13.091  12.841  -16.393 1.00 39.61 ? 254  GLY I O   1 
ATOM   4406 N N   . LYS C 3  263 ? 11.085  11.975  -16.913 1.00 37.85 ? 255  LYS I N   1 
ATOM   4407 C CA  . LYS C 3  263 ? 10.396  12.819  -15.944 1.00 37.39 ? 255  LYS I CA  1 
ATOM   4408 C C   . LYS C 3  263 ? 9.772   12.072  -14.769 1.00 36.79 ? 255  LYS I C   1 
ATOM   4409 O O   . LYS C 3  263 ? 8.994   12.652  -14.013 1.00 37.06 ? 255  LYS I O   1 
ATOM   4410 C CB  . LYS C 3  263 ? 9.321   13.655  -16.647 1.00 37.88 ? 255  LYS I CB  1 
ATOM   4411 C CG  . LYS C 3  263 ? 9.874   14.617  -17.686 1.00 38.34 ? 255  LYS I CG  1 
ATOM   4412 C CD  . LYS C 3  263 ? 10.905  15.552  -17.070 1.00 40.01 ? 255  LYS I CD  1 
ATOM   4413 C CE  . LYS C 3  263 ? 11.524  16.461  -18.120 1.00 39.80 ? 255  LYS I CE  1 
ATOM   4414 N NZ  . LYS C 3  263 ? 12.559  17.352  -17.531 1.00 39.54 ? 255  LYS I NZ  1 
ATOM   4415 N N   . MET C 3  264 ? 10.112  10.796  -14.608 1.00 37.05 ? 256  MET I N   1 
ATOM   4416 C CA  . MET C 3  264 ? 9.568   10.008  -13.502 1.00 36.08 ? 256  MET I CA  1 
ATOM   4417 C C   . MET C 3  264 ? 9.871   10.678  -12.168 1.00 37.04 ? 256  MET I C   1 
ATOM   4418 O O   . MET C 3  264 ? 8.978   10.879  -11.345 1.00 36.78 ? 256  MET I O   1 
ATOM   4419 C CB  . MET C 3  264 ? 10.155  8.595   -13.504 1.00 34.06 ? 256  MET I CB  1 
ATOM   4420 C CG  . MET C 3  264 ? 9.785   7.766   -12.271 1.00 30.62 ? 256  MET I CG  1 
ATOM   4421 S SD  . MET C 3  264 ? 8.001   7.528   -12.054 1.00 28.41 ? 256  MET I SD  1 
ATOM   4422 C CE  . MET C 3  264 ? 7.748   6.079   -13.034 1.00 28.10 ? 256  MET I CE  1 
ATOM   4423 N N   . GLN C 3  265 ? 11.137  11.025  -11.959 1.00 37.78 ? 257  GLN I N   1 
ATOM   4424 C CA  . GLN C 3  265 ? 11.548  11.672  -10.721 1.00 39.01 ? 257  GLN I CA  1 
ATOM   4425 C C   . GLN C 3  265 ? 10.775  12.967  -10.508 1.00 38.87 ? 257  GLN I C   1 
ATOM   4426 O O   . GLN C 3  265 ? 10.384  13.290  -9.388  1.00 38.96 ? 257  GLN I O   1 
ATOM   4427 C CB  . GLN C 3  265 ? 13.052  11.956  -10.748 1.00 41.19 ? 257  GLN I CB  1 
ATOM   4428 C CG  . GLN C 3  265 ? 13.563  12.716  -9.537  1.00 44.48 ? 257  GLN I CG  1 
ATOM   4429 C CD  . GLN C 3  265 ? 13.191  12.046  -8.229  1.00 47.25 ? 257  GLN I CD  1 
ATOM   4430 O OE1 . GLN C 3  265 ? 13.540  10.890  -7.984  1.00 48.80 ? 257  GLN I OE1 1 
ATOM   4431 N NE2 . GLN C 3  265 ? 12.477  12.773  -7.378  1.00 48.00 ? 257  GLN I NE2 1 
ATOM   4432 N N   . GLN C 3  266 ? 10.551  13.706  -11.590 1.00 39.24 ? 258  GLN I N   1 
ATOM   4433 C CA  . GLN C 3  266 ? 9.820   14.965  -11.511 1.00 38.48 ? 258  GLN I CA  1 
ATOM   4434 C C   . GLN C 3  266 ? 8.369   14.742  -11.092 1.00 36.84 ? 258  GLN I C   1 
ATOM   4435 O O   . GLN C 3  266 ? 7.809   15.527  -10.325 1.00 37.53 ? 258  GLN I O   1 
ATOM   4436 C CB  . GLN C 3  266 ? 9.870   15.685  -12.861 1.00 40.92 ? 258  GLN I CB  1 
ATOM   4437 C CG  . GLN C 3  266 ? 9.062   16.969  -12.913 1.00 42.60 ? 258  GLN I CG  1 
ATOM   4438 C CD  . GLN C 3  266 ? 9.320   17.762  -14.178 1.00 44.18 ? 258  GLN I CD  1 
ATOM   4439 O OE1 . GLN C 3  266 ? 10.410  18.304  -14.373 1.00 45.40 ? 258  GLN I OE1 1 
ATOM   4440 N NE2 . GLN C 3  266 ? 8.320   17.828  -15.051 1.00 44.68 ? 258  GLN I NE2 1 
ATOM   4441 N N   . VAL C 3  267 ? 7.763   13.672  -11.593 1.00 35.31 ? 259  VAL I N   1 
ATOM   4442 C CA  . VAL C 3  267 ? 6.378   13.359  -11.251 1.00 34.05 ? 259  VAL I CA  1 
ATOM   4443 C C   . VAL C 3  267 ? 6.274   12.883  -9.804  1.00 33.73 ? 259  VAL I C   1 
ATOM   4444 O O   . VAL C 3  267 ? 5.353   13.262  -9.079  1.00 33.46 ? 259  VAL I O   1 
ATOM   4445 C CB  . VAL C 3  267 ? 5.804   12.267  -12.177 1.00 33.72 ? 259  VAL I CB  1 
ATOM   4446 C CG1 . VAL C 3  267 ? 4.395   11.889  -11.729 1.00 33.62 ? 259  VAL I CG1 1 
ATOM   4447 C CG2 . VAL C 3  267 ? 5.781   12.766  -13.618 1.00 33.16 ? 259  VAL I CG2 1 
ATOM   4448 N N   . GLU C 3  268 ? 7.222   12.051  -9.388  1.00 34.03 ? 260  GLU I N   1 
ATOM   4449 C CA  . GLU C 3  268 ? 7.231   11.534  -8.024  1.00 34.53 ? 260  GLU I CA  1 
ATOM   4450 C C   . GLU C 3  268 ? 7.281   12.679  -7.022  1.00 35.66 ? 260  GLU I C   1 
ATOM   4451 O O   . GLU C 3  268 ? 6.534   12.691  -6.045  1.00 35.78 ? 260  GLU I O   1 
ATOM   4452 C CB  . GLU C 3  268 ? 8.432   10.613  -7.814  1.00 33.31 ? 260  GLU I CB  1 
ATOM   4453 C CG  . GLU C 3  268 ? 8.388   9.342   -8.638  1.00 32.76 ? 260  GLU I CG  1 
ATOM   4454 C CD  . GLU C 3  268 ? 9.605   8.468   -8.420  1.00 33.71 ? 260  GLU I CD  1 
ATOM   4455 O OE1 . GLU C 3  268 ? 10.733  8.973   -8.592  1.00 35.64 ? 260  GLU I OE1 1 
ATOM   4456 O OE2 . GLU C 3  268 ? 9.436   7.276   -8.084  1.00 32.69 ? 260  GLU I OE2 1 
ATOM   4457 N N   . ASN C 3  269 ? 8.163   13.642  -7.268  1.00 36.80 ? 261  ASN I N   1 
ATOM   4458 C CA  . ASN C 3  269 ? 8.298   14.789  -6.379  1.00 39.32 ? 261  ASN I CA  1 
ATOM   4459 C C   . ASN C 3  269 ? 7.016   15.613  -6.346  1.00 39.06 ? 261  ASN I C   1 
ATOM   4460 O O   . ASN C 3  269 ? 6.711   16.260  -5.344  1.00 40.37 ? 261  ASN I O   1 
ATOM   4461 C CB  . ASN C 3  269 ? 9.472   15.665  -6.825  1.00 41.36 ? 261  ASN I CB  1 
ATOM   4462 C CG  . ASN C 3  269 ? 10.816  15.019  -6.551  1.00 43.52 ? 261  ASN I CG  1 
ATOM   4463 O OD1 . ASN C 3  269 ? 11.849  15.472  -7.044  1.00 45.51 ? 261  ASN I OD1 1 
ATOM   4464 N ND2 . ASN C 3  269 ? 10.810  13.958  -5.750  1.00 43.69 ? 261  ASN I ND2 1 
ATOM   4465 N N   . GLY C 3  270 ? 6.264   15.575  -7.441  1.00 39.07 ? 262  GLY I N   1 
ATOM   4466 C CA  . GLY C 3  270 ? 5.026   16.327  -7.518  1.00 38.27 ? 262  GLY I CA  1 
ATOM   4467 C C   . GLY C 3  270 ? 3.828   15.616  -6.918  1.00 37.77 ? 262  GLY I C   1 
ATOM   4468 O O   . GLY C 3  270 ? 2.766   16.217  -6.756  1.00 38.40 ? 262  GLY I O   1 
ATOM   4469 N N   . LEU C 3  271 ? 3.987   14.336  -6.590  1.00 37.01 ? 263  LEU I N   1 
ATOM   4470 C CA  . LEU C 3  271 ? 2.896   13.565  -6.002  1.00 36.50 ? 263  LEU I CA  1 
ATOM   4471 C C   . LEU C 3  271 ? 2.438   14.182  -4.684  1.00 37.85 ? 263  LEU I C   1 
ATOM   4472 O O   . LEU C 3  271 ? 3.243   14.424  -3.784  1.00 37.87 ? 263  LEU I O   1 
ATOM   4473 C CB  . LEU C 3  271 ? 3.329   12.114  -5.768  1.00 35.40 ? 263  LEU I CB  1 
ATOM   4474 C CG  . LEU C 3  271 ? 3.626   11.261  -7.004  1.00 34.67 ? 263  LEU I CG  1 
ATOM   4475 C CD1 . LEU C 3  271 ? 4.075   9.879   -6.564  1.00 33.49 ? 263  LEU I CD1 1 
ATOM   4476 C CD2 . LEU C 3  271 ? 2.382   11.165  -7.884  1.00 34.61 ? 263  LEU I CD2 1 
ATOM   4477 N N   . SER C 3  272 ? 1.138   14.433  -4.579  1.00 38.18 ? 264  SER I N   1 
ATOM   4478 C CA  . SER C 3  272 ? 0.560   15.025  -3.380  1.00 39.36 ? 264  SER I CA  1 
ATOM   4479 C C   . SER C 3  272 ? -0.955  14.898  -3.431  1.00 40.63 ? 264  SER I C   1 
ATOM   4480 O O   . SER C 3  272 ? -1.520  14.543  -4.466  1.00 40.09 ? 264  SER I O   1 
ATOM   4481 C CB  . SER C 3  272 ? 0.945   16.503  -3.284  1.00 39.99 ? 264  SER I CB  1 
ATOM   4482 O OG  . SER C 3  272 ? 0.415   17.238  -4.377  1.00 40.49 ? 264  SER I OG  1 
ATOM   4483 N N   . GLU C 3  273 ? -1.611  15.187  -2.311  1.00 41.74 ? 265  GLU I N   1 
ATOM   4484 C CA  . GLU C 3  273 ? -3.066  15.114  -2.243  1.00 43.52 ? 265  GLU I CA  1 
ATOM   4485 C C   . GLU C 3  273 ? -3.648  16.133  -3.212  1.00 43.67 ? 265  GLU I C   1 
ATOM   4486 O O   . GLU C 3  273 ? -4.658  15.878  -3.873  1.00 44.05 ? 265  GLU I O   1 
ATOM   4487 C CB  . GLU C 3  273 ? -3.549  15.415  -0.820  1.00 45.01 ? 265  GLU I CB  1 
ATOM   4488 C CG  . GLU C 3  273 ? -3.112  14.390  0.223   1.00 47.94 ? 265  GLU I CG  1 
ATOM   4489 C CD  . GLU C 3  273 ? -3.840  13.060  0.091   1.00 49.50 ? 265  GLU I CD  1 
ATOM   4490 O OE1 . GLU C 3  273 ? -3.515  12.124  0.854   1.00 50.31 ? 265  GLU I OE1 1 
ATOM   4491 O OE2 . GLU C 3  273 ? -4.741  12.952  -0.768  1.00 50.44 ? 265  GLU I OE2 1 
ATOM   4492 N N   . LYS C 3  274 ? -2.997  17.289  -3.292  1.00 43.33 ? 266  LYS I N   1 
ATOM   4493 C CA  . LYS C 3  274 ? -3.427  18.363  -4.179  1.00 43.54 ? 266  LYS I CA  1 
ATOM   4494 C C   . LYS C 3  274 ? -3.387  17.903  -5.632  1.00 43.17 ? 266  LYS I C   1 
ATOM   4495 O O   . LYS C 3  274 ? -4.340  18.108  -6.385  1.00 43.81 ? 266  LYS I O   1 
ATOM   4496 C CB  . LYS C 3  274 ? -2.521  19.585  -4.000  1.00 43.12 ? 266  LYS I CB  1 
ATOM   4497 C CG  . LYS C 3  274 ? -2.871  20.759  -4.900  1.00 44.06 ? 266  LYS I CG  1 
ATOM   4498 N N   . THR C 3  275 ? -2.278  17.280  -6.020  1.00 43.01 ? 267  THR I N   1 
ATOM   4499 C CA  . THR C 3  275 ? -2.110  16.791  -7.381  1.00 42.48 ? 267  THR I CA  1 
ATOM   4500 C C   . THR C 3  275 ? -3.148  15.727  -7.717  1.00 42.52 ? 267  THR I C   1 
ATOM   4501 O O   . THR C 3  275 ? -3.714  15.726  -8.811  1.00 42.36 ? 267  THR I O   1 
ATOM   4502 C CB  . THR C 3  275 ? -0.700  16.202  -7.588  1.00 42.37 ? 267  THR I CB  1 
ATOM   4503 O OG1 . THR C 3  275 ? 0.273   17.245  -7.463  1.00 42.48 ? 267  THR I OG1 1 
ATOM   4504 C CG2 . THR C 3  275 ? -0.577  15.575  -8.966  1.00 41.37 ? 267  THR I CG2 1 
ATOM   4505 N N   . LEU C 3  276 ? -3.397  14.824  -6.776  1.00 42.57 ? 268  LEU I N   1 
ATOM   4506 C CA  . LEU C 3  276 ? -4.374  13.765  -6.986  1.00 42.83 ? 268  LEU I CA  1 
ATOM   4507 C C   . LEU C 3  276 ? -5.754  14.369  -7.217  1.00 43.85 ? 268  LEU I C   1 
ATOM   4508 O O   . LEU C 3  276 ? -6.446  14.018  -8.175  1.00 43.36 ? 268  LEU I O   1 
ATOM   4509 C CB  . LEU C 3  276 ? -4.413  12.828  -5.777  1.00 42.67 ? 268  LEU I CB  1 
ATOM   4510 C CG  . LEU C 3  276 ? -5.412  11.670  -5.861  1.00 42.69 ? 268  LEU I CG  1 
ATOM   4511 C CD1 . LEU C 3  276 ? -5.154  10.854  -7.120  1.00 42.86 ? 268  LEU I CD1 1 
ATOM   4512 C CD2 . LEU C 3  276 ? -5.287  10.799  -4.625  1.00 42.06 ? 268  LEU I CD2 1 
ATOM   4513 N N   . ARG C 3  277 ? -6.147  15.283  -6.334  1.00 44.28 ? 269  ARG I N   1 
ATOM   4514 C CA  . ARG C 3  277 ? -7.440  15.944  -6.441  1.00 44.60 ? 269  ARG I CA  1 
ATOM   4515 C C   . ARG C 3  277 ? -7.569  16.605  -7.810  1.00 44.77 ? 269  ARG I C   1 
ATOM   4516 O O   . ARG C 3  277 ? -8.617  16.530  -8.452  1.00 44.83 ? 269  ARG I O   1 
ATOM   4517 C CB  . ARG C 3  277 ? -7.585  16.999  -5.340  1.00 44.66 ? 269  ARG I CB  1 
ATOM   4518 N N   . LYS C 3  278 ? -6.491  17.246  -8.248  1.00 45.33 ? 270  LYS I N   1 
ATOM   4519 C CA  . LYS C 3  278 ? -6.464  17.922  -9.539  1.00 46.25 ? 270  LYS I CA  1 
ATOM   4520 C C   . LYS C 3  278 ? -6.769  16.958  -10.682 1.00 46.32 ? 270  LYS I C   1 
ATOM   4521 O O   . LYS C 3  278 ? -7.683  17.189  -11.474 1.00 47.15 ? 270  LYS I O   1 
ATOM   4522 C CB  . LYS C 3  278 ? -5.093  18.563  -9.769  1.00 46.92 ? 270  LYS I CB  1 
ATOM   4523 C CG  . LYS C 3  278 ? -4.903  19.134  -11.166 1.00 48.05 ? 270  LYS I CG  1 
ATOM   4524 C CD  . LYS C 3  278 ? -3.490  19.656  -11.371 1.00 49.14 ? 270  LYS I CD  1 
ATOM   4525 C CE  . LYS C 3  278 ? -3.283  20.132  -12.800 1.00 50.32 ? 270  LYS I CE  1 
ATOM   4526 N NZ  . LYS C 3  278 ? -1.910  20.667  -13.021 1.00 51.45 ? 270  LYS I NZ  1 
ATOM   4527 N N   . TRP C 3  279 ? -5.997  15.880  -10.765 1.00 45.60 ? 271  TRP I N   1 
ATOM   4528 C CA  . TRP C 3  279 ? -6.185  14.891  -11.817 1.00 44.87 ? 271  TRP I CA  1 
ATOM   4529 C C   . TRP C 3  279 ? -7.638  14.451  -11.934 1.00 45.28 ? 271  TRP I C   1 
ATOM   4530 O O   . TRP C 3  279 ? -8.214  14.461  -13.022 1.00 45.24 ? 271  TRP I O   1 
ATOM   4531 C CB  . TRP C 3  279 ? -5.305  13.663  -11.566 1.00 42.61 ? 271  TRP I CB  1 
ATOM   4532 C CG  . TRP C 3  279 ? -3.832  13.917  -11.699 1.00 40.97 ? 271  TRP I CG  1 
ATOM   4533 C CD1 . TRP C 3  279 ? -3.231  14.941  -12.379 1.00 41.17 ? 271  TRP I CD1 1 
ATOM   4534 C CD2 . TRP C 3  279 ? -2.771  13.095  -11.197 1.00 40.35 ? 271  TRP I CD2 1 
ATOM   4535 N NE1 . TRP C 3  279 ? -1.864  14.804  -12.332 1.00 40.31 ? 271  TRP I NE1 1 
ATOM   4536 C CE2 . TRP C 3  279 ? -1.555  13.680  -11.614 1.00 40.34 ? 271  TRP I CE2 1 
ATOM   4537 C CE3 . TRP C 3  279 ? -2.731  11.919  -10.436 1.00 40.04 ? 271  TRP I CE3 1 
ATOM   4538 C CZ2 . TRP C 3  279 ? -0.310  13.127  -11.296 1.00 40.14 ? 271  TRP I CZ2 1 
ATOM   4539 C CZ3 . TRP C 3  279 ? -1.492  11.370  -10.120 1.00 39.94 ? 271  TRP I CZ3 1 
ATOM   4540 C CH2 . TRP C 3  279 ? -0.299  11.976  -10.550 1.00 39.93 ? 271  TRP I CH2 1 
ATOM   4541 N N   . LEU C 3  280 ? -8.224  14.067  -10.806 1.00 46.23 ? 272  LEU I N   1 
ATOM   4542 C CA  . LEU C 3  280 ? -9.606  13.607  -10.771 1.00 47.36 ? 272  LEU I CA  1 
ATOM   4543 C C   . LEU C 3  280 ? -10.586 14.659  -11.276 1.00 48.19 ? 272  LEU I C   1 
ATOM   4544 O O   . LEU C 3  280 ? -11.630 14.327  -11.837 1.00 49.11 ? 272  LEU I O   1 
ATOM   4545 C CB  . LEU C 3  280 ? -9.983  13.206  -9.344  1.00 47.33 ? 272  LEU I CB  1 
ATOM   4546 C CG  . LEU C 3  280 ? -9.116  12.127  -8.693  1.00 47.43 ? 272  LEU I CG  1 
ATOM   4547 C CD1 . LEU C 3  280 ? -9.548  11.924  -7.253  1.00 48.42 ? 272  LEU I CD1 1 
ATOM   4548 C CD2 . LEU C 3  280 ? -9.236  10.831  -9.476  1.00 48.36 ? 272  LEU I CD2 1 
ATOM   4549 N N   . LYS C 3  281 ? -10.242 15.927  -11.081 1.00 48.67 ? 273  LYS I N   1 
ATOM   4550 C CA  . LYS C 3  281 ? -11.104 17.027  -11.500 1.00 48.78 ? 273  LYS I CA  1 
ATOM   4551 C C   . LYS C 3  281 ? -10.939 17.442  -12.960 1.00 48.85 ? 273  LYS I C   1 
ATOM   4552 O O   . LYS C 3  281 ? -11.896 17.895  -13.590 1.00 49.55 ? 273  LYS I O   1 
ATOM   4553 C CB  . LYS C 3  281 ? -10.865 18.241  -10.597 1.00 48.80 ? 273  LYS I CB  1 
ATOM   4554 C CG  . LYS C 3  281 ? -11.693 19.465  -10.957 1.00 49.32 ? 273  LYS I CG  1 
ATOM   4555 N N   . MET C 3  282 ? -9.736  17.289  -13.503 1.00 48.05 ? 274  MET I N   1 
ATOM   4556 C CA  . MET C 3  282 ? -9.486  17.688  -14.885 1.00 47.67 ? 274  MET I CA  1 
ATOM   4557 C C   . MET C 3  282 ? -9.663  16.571  -15.911 1.00 45.93 ? 274  MET I C   1 
ATOM   4558 O O   . MET C 3  282 ? -9.404  16.766  -17.099 1.00 46.52 ? 274  MET I O   1 
ATOM   4559 C CB  . MET C 3  282 ? -8.082  18.285  -15.008 1.00 49.23 ? 274  MET I CB  1 
ATOM   4560 C CG  . MET C 3  282 ? -7.827  19.432  -14.045 1.00 52.37 ? 274  MET I CG  1 
ATOM   4561 S SD  . MET C 3  282 ? -6.296  20.316  -14.378 1.00 55.85 ? 274  MET I SD  1 
ATOM   4562 C CE  . MET C 3  282 ? -6.930  21.824  -15.113 1.00 56.36 ? 274  MET I CE  1 
ATOM   4563 N N   . PHE C 3  283 ? -10.108 15.406  -15.455 1.00 43.57 ? 275  PHE I N   1 
ATOM   4564 C CA  . PHE C 3  283 ? -10.318 14.267  -16.343 1.00 40.97 ? 275  PHE I CA  1 
ATOM   4565 C C   . PHE C 3  283 ? -11.374 14.538  -17.411 1.00 40.04 ? 275  PHE I C   1 
ATOM   4566 O O   . PHE C 3  283 ? -12.433 15.098  -17.127 1.00 39.41 ? 275  PHE I O   1 
ATOM   4567 C CB  . PHE C 3  283 ? -10.737 13.036  -15.532 1.00 40.28 ? 275  PHE I CB  1 
ATOM   4568 C CG  . PHE C 3  283 ? -9.591  12.149  -15.125 1.00 39.85 ? 275  PHE I CG  1 
ATOM   4569 C CD1 . PHE C 3  283 ? -9.753  11.215  -14.106 1.00 39.75 ? 275  PHE I CD1 1 
ATOM   4570 C CD2 . PHE C 3  283 ? -8.361  12.224  -15.773 1.00 39.77 ? 275  PHE I CD2 1 
ATOM   4571 C CE1 . PHE C 3  283 ? -8.710  10.369  -13.738 1.00 38.88 ? 275  PHE I CE1 1 
ATOM   4572 C CE2 . PHE C 3  283 ? -7.312  11.383  -15.414 1.00 38.86 ? 275  PHE I CE2 1 
ATOM   4573 C CZ  . PHE C 3  283 ? -7.487  10.453  -14.394 1.00 39.49 ? 275  PHE I CZ  1 
ATOM   4574 N N   . LYS C 3  284 ? -11.071 14.132  -18.639 1.00 38.89 ? 276  LYS I N   1 
ATOM   4575 C CA  . LYS C 3  284 ? -11.986 14.284  -19.765 1.00 38.14 ? 276  LYS I CA  1 
ATOM   4576 C C   . LYS C 3  284 ? -11.997 12.975  -20.539 1.00 36.32 ? 276  LYS I C   1 
ATOM   4577 O O   . LYS C 3  284 ? -10.953 12.345  -20.707 1.00 35.19 ? 276  LYS I O   1 
ATOM   4578 C CB  . LYS C 3  284 ? -11.531 15.412  -20.692 1.00 39.70 ? 276  LYS I CB  1 
ATOM   4579 C CG  . LYS C 3  284 ? -11.731 16.809  -20.135 1.00 42.35 ? 276  LYS I CG  1 
ATOM   4580 C CD  . LYS C 3  284 ? -13.201 17.097  -19.888 1.00 45.01 ? 276  LYS I CD  1 
ATOM   4581 C CE  . LYS C 3  284 ? -13.421 18.559  -19.534 1.00 45.88 ? 276  LYS I CE  1 
ATOM   4582 N NZ  . LYS C 3  284 ? -13.007 19.454  -20.649 1.00 46.47 ? 276  LYS I NZ  1 
ATOM   4583 N N   . LYS C 3  285 ? -13.173 12.555  -20.995 1.00 34.91 ? 277  LYS I N   1 
ATOM   4584 C CA  . LYS C 3  285 ? -13.277 11.319  -21.760 1.00 34.48 ? 277  LYS I CA  1 
ATOM   4585 C C   . LYS C 3  285 ? -12.563 11.507  -23.093 1.00 34.39 ? 277  LYS I C   1 
ATOM   4586 O O   . LYS C 3  285 ? -12.833 12.461  -23.822 1.00 34.23 ? 277  LYS I O   1 
ATOM   4587 C CB  . LYS C 3  285 ? -14.743 10.959  -22.004 1.00 36.08 ? 277  LYS I CB  1 
ATOM   4588 C CG  . LYS C 3  285 ? -15.545 10.742  -20.736 1.00 38.20 ? 277  LYS I CG  1 
ATOM   4589 C CD  . LYS C 3  285 ? -16.959 10.302  -21.061 1.00 40.40 ? 277  LYS I CD  1 
ATOM   4590 C CE  . LYS C 3  285 ? -17.801 10.161  -19.805 1.00 41.43 ? 277  LYS I CE  1 
ATOM   4591 N NZ  . LYS C 3  285 ? -19.191 9.734   -20.125 1.00 41.89 ? 277  LYS I NZ  1 
ATOM   4592 N N   A ARG C 3  286 ? -11.650 10.596  -23.410 0.20 33.71 ? 278  ARG I N   1 
ATOM   4593 N N   B ARG C 3  286 ? -11.653 10.590  -23.406 0.72 33.23 ? 278  ARG I N   1 
ATOM   4594 C CA  A ARG C 3  286 ? -10.903 10.674  -24.658 0.21 33.34 ? 278  ARG I CA  1 
ATOM   4595 C CA  B ARG C 3  286 ? -10.889 10.659  -24.643 0.73 33.12 ? 278  ARG I CA  1 
ATOM   4596 C C   A ARG C 3  286 ? -10.716 9.305   -25.298 0.27 32.85 ? 278  ARG I C   1 
ATOM   4597 C C   B ARG C 3  286 ? -10.733 9.293   -25.296 0.63 32.45 ? 278  ARG I C   1 
ATOM   4598 O O   A ARG C 3  286 ? -10.476 8.311   -24.612 0.10 32.57 ? 278  ARG I O   1 
ATOM   4599 O O   B ARG C 3  286 ? -10.536 8.286   -24.614 0.90 31.03 ? 278  ARG I O   1 
ATOM   4600 C CB  A ARG C 3  286 ? -9.542  11.328  -24.412 0.28 33.57 ? 278  ARG I CB  1 
ATOM   4601 C CB  B ARG C 3  286 ? -9.509  11.253  -24.358 0.72 33.53 ? 278  ARG I CB  1 
ATOM   4602 C CG  A ARG C 3  286 ? -9.615  12.832  -24.185 0.13 34.04 ? 278  ARG I CG  1 
ATOM   4603 C CG  B ARG C 3  286 ? -9.543  12.720  -23.966 0.77 34.22 ? 278  ARG I CG  1 
ATOM   4604 C CD  A ARG C 3  286 ? -9.912  13.566  -25.486 0.18 34.49 ? 278  ARG I CD  1 
ATOM   4605 C CD  B ARG C 3  286 ? -9.538  13.603  -25.201 0.27 34.66 ? 278  ARG I CD  1 
ATOM   4606 N NE  A ARG C 3  286 ? -10.067 15.005  -25.292 0.54 35.25 ? 278  ARG I NE  1 
ATOM   4607 N NE  B ARG C 3  286 ? -8.207  13.661  -25.799 0.44 35.27 ? 278  ARG I NE  1 
ATOM   4608 C CZ  A ARG C 3  286 ? -11.167 15.586  -24.823 0.47 35.62 ? 278  ARG I CZ  1 
ATOM   4609 C CZ  B ARG C 3  286 ? -7.195  14.359  -25.293 0.53 35.59 ? 278  ARG I CZ  1 
ATOM   4610 N NH1 A ARG C 3  286 ? -12.222 14.853  -24.499 0.50 35.97 ? 278  ARG I NH1 1 
ATOM   4611 N NH1 B ARG C 3  286 ? -7.363  15.062  -24.181 0.50 36.18 ? 278  ARG I NH1 1 
ATOM   4612 N NH2 A ARG C 3  286 ? -11.214 16.903  -24.680 0.50 35.60 ? 278  ARG I NH2 1 
ATOM   4613 N NH2 B ARG C 3  286 ? -6.013  14.350  -25.890 0.50 35.52 ? 278  ARG I NH2 1 
ATOM   4614 N N   . GLN C 3  287 ? -10.828 9.266   -26.622 1.00 32.16 ? 279  GLN I N   1 
ATOM   4615 C CA  . GLN C 3  287 ? -10.681 8.029   -27.377 1.00 32.15 ? 279  GLN I CA  1 
ATOM   4616 C C   . GLN C 3  287 ? -9.210  7.633   -27.365 1.00 31.17 ? 279  GLN I C   1 
ATOM   4617 O O   . GLN C 3  287 ? -8.362  8.348   -27.900 1.00 31.22 ? 279  GLN I O   1 
ATOM   4618 C CB  . GLN C 3  287 ? -11.148 8.245   -28.819 1.00 32.84 ? 279  GLN I CB  1 
ATOM   4619 C CG  . GLN C 3  287 ? -11.257 6.983   -29.653 1.00 34.18 ? 279  GLN I CG  1 
ATOM   4620 C CD  . GLN C 3  287 ? -12.288 6.018   -29.109 1.00 34.05 ? 279  GLN I CD  1 
ATOM   4621 O OE1 . GLN C 3  287 ? -13.277 6.427   -28.501 1.00 35.87 ? 279  GLN I OE1 1 
ATOM   4622 N NE2 . GLN C 3  287 ? -12.071 4.728   -29.340 1.00 36.45 ? 279  GLN I NE2 1 
ATOM   4623 N N   . LEU C 3  288 ? -8.909  6.491   -26.758 1.00 31.08 ? 280  LEU I N   1 
ATOM   4624 C CA  . LEU C 3  288 ? -7.532  6.030   -26.672 1.00 30.84 ? 280  LEU I CA  1 
ATOM   4625 C C   . LEU C 3  288 ? -7.346  4.583   -27.095 1.00 31.09 ? 280  LEU I C   1 
ATOM   4626 O O   . LEU C 3  288 ? -8.225  3.745   -26.909 1.00 30.15 ? 280  LEU I O   1 
ATOM   4627 C CB  . LEU C 3  288 ? -7.017  6.165   -25.235 1.00 32.00 ? 280  LEU I CB  1 
ATOM   4628 C CG  . LEU C 3  288 ? -7.065  7.527   -24.545 1.00 32.19 ? 280  LEU I CG  1 
ATOM   4629 C CD1 . LEU C 3  288 ? -6.614  7.367   -23.101 1.00 33.30 ? 280  LEU I CD1 1 
ATOM   4630 C CD2 . LEU C 3  288 ? -6.176  8.519   -25.280 1.00 33.29 ? 280  LEU I CD2 1 
ATOM   4631 N N   . GLU C 3  289 ? -6.186  4.306   -27.677 1.00 32.17 ? 281  GLU I N   1 
ATOM   4632 C CA  . GLU C 3  289 ? -5.825  2.954   -28.064 1.00 33.57 ? 281  GLU I CA  1 
ATOM   4633 C C   . GLU C 3  289 ? -4.911  2.594   -26.895 1.00 32.74 ? 281  GLU I C   1 
ATOM   4634 O O   . GLU C 3  289 ? -3.689  2.721   -26.982 1.00 33.51 ? 281  GLU I O   1 
ATOM   4635 C CB  . GLU C 3  289 ? -5.048  2.957   -29.381 1.00 36.22 ? 281  GLU I CB  1 
ATOM   4636 C CG  . GLU C 3  289 ? -4.734  1.569   -29.909 1.00 40.70 ? 281  GLU I CG  1 
ATOM   4637 C CD  . GLU C 3  289 ? -4.085  1.595   -31.281 1.00 43.24 ? 281  GLU I CD  1 
ATOM   4638 O OE1 . GLU C 3  289 ? -3.728  0.510   -31.784 1.00 44.93 ? 281  GLU I OE1 1 
ATOM   4639 O OE2 . GLU C 3  289 ? -3.934  2.696   -31.857 1.00 44.70 ? 281  GLU I OE2 1 
ATOM   4640 N N   . LEU C 3  290 ? -5.526  2.184   -25.790 1.00 31.52 ? 282  LEU I N   1 
ATOM   4641 C CA  . LEU C 3  290 ? -4.798  1.856   -24.568 1.00 30.42 ? 282  LEU I CA  1 
ATOM   4642 C C   . LEU C 3  290 ? -4.096  0.508   -24.515 1.00 30.20 ? 282  LEU I C   1 
ATOM   4643 O O   . LEU C 3  290 ? -4.689  -0.539  -24.779 1.00 29.72 ? 282  LEU I O   1 
ATOM   4644 C CB  . LEU C 3  290 ? -5.733  1.964   -23.358 1.00 29.13 ? 282  LEU I CB  1 
ATOM   4645 C CG  . LEU C 3  290 ? -5.095  1.676   -21.992 1.00 29.52 ? 282  LEU I CG  1 
ATOM   4646 C CD1 . LEU C 3  290 ? -4.077  2.758   -21.662 1.00 30.76 ? 282  LEU I CD1 1 
ATOM   4647 C CD2 . LEU C 3  290 ? -6.172  1.617   -20.922 1.00 29.49 ? 282  LEU I CD2 1 
ATOM   4648 N N   . TYR C 3  291 ? -2.821  0.557   -24.150 1.00 30.15 ? 283  TYR I N   1 
ATOM   4649 C CA  . TYR C 3  291 ? -2.001  -0.636  -24.004 1.00 31.42 ? 283  TYR I CA  1 
ATOM   4650 C C   . TYR C 3  291 ? -1.525  -0.654  -22.555 1.00 30.03 ? 283  TYR I C   1 
ATOM   4651 O O   . TYR C 3  291 ? -0.717  0.178   -22.149 1.00 29.02 ? 283  TYR I O   1 
ATOM   4652 C CB  . TYR C 3  291 ? -0.815  -0.580  -24.966 1.00 33.69 ? 283  TYR I CB  1 
ATOM   4653 C CG  . TYR C 3  291 ? -1.211  -0.785  -26.411 1.00 36.79 ? 283  TYR I CG  1 
ATOM   4654 C CD1 . TYR C 3  291 ? -1.526  -2.055  -26.894 1.00 38.18 ? 283  TYR I CD1 1 
ATOM   4655 C CD2 . TYR C 3  291 ? -1.302  0.294   -27.290 1.00 38.19 ? 283  TYR I CD2 1 
ATOM   4656 C CE1 . TYR C 3  291 ? -1.924  -2.246  -28.218 1.00 39.06 ? 283  TYR I CE1 1 
ATOM   4657 C CE2 . TYR C 3  291 ? -1.699  0.115   -28.614 1.00 39.06 ? 283  TYR I CE2 1 
ATOM   4658 C CZ  . TYR C 3  291 ? -2.009  -1.157  -29.070 1.00 39.91 ? 283  TYR I CZ  1 
ATOM   4659 O OH  . TYR C 3  291 ? -2.411  -1.336  -30.374 1.00 40.59 ? 283  TYR I OH  1 
ATOM   4660 N N   . LEU C 3  292 ? -2.048  -1.597  -21.779 1.00 30.46 ? 284  LEU I N   1 
ATOM   4661 C CA  . LEU C 3  292 ? -1.698  -1.714  -20.367 1.00 30.63 ? 284  LEU I CA  1 
ATOM   4662 C C   . LEU C 3  292 ? -1.220  -3.124  -20.031 1.00 30.49 ? 284  LEU I C   1 
ATOM   4663 O O   . LEU C 3  292 ? -1.877  -4.109  -20.361 1.00 31.28 ? 284  LEU I O   1 
ATOM   4664 C CB  . LEU C 3  292 ? -2.912  -1.365  -19.504 1.00 30.21 ? 284  LEU I CB  1 
ATOM   4665 C CG  . LEU C 3  292 ? -2.716  -1.337  -17.988 1.00 28.89 ? 284  LEU I CG  1 
ATOM   4666 C CD1 . LEU C 3  292 ? -1.792  -0.190  -17.612 1.00 29.84 ? 284  LEU I CD1 1 
ATOM   4667 C CD2 . LEU C 3  292 ? -4.063  -1.177  -17.306 1.00 30.28 ? 284  LEU I CD2 1 
ATOM   4668 N N   . PRO C 3  293 ? -0.066  -3.234  -19.356 1.00 31.05 ? 285  PRO I N   1 
ATOM   4669 C CA  . PRO C 3  293 ? 0.484   -4.540  -18.985 1.00 31.46 ? 285  PRO I CA  1 
ATOM   4670 C C   . PRO C 3  293 ? -0.408  -5.340  -18.037 1.00 33.11 ? 285  PRO I C   1 
ATOM   4671 O O   . PRO C 3  293 ? -1.097  -4.776  -17.187 1.00 32.93 ? 285  PRO I O   1 
ATOM   4672 C CB  . PRO C 3  293 ? 1.819   -4.181  -18.333 1.00 31.16 ? 285  PRO I CB  1 
ATOM   4673 C CG  . PRO C 3  293 ? 2.184   -2.874  -18.975 1.00 31.71 ? 285  PRO I CG  1 
ATOM   4674 C CD  . PRO C 3  293 ? 0.867   -2.152  -18.999 1.00 29.81 ? 285  PRO I CD  1 
ATOM   4675 N N   . LYS C 3  294 ? -0.401  -6.658  -18.208 1.00 33.63 ? 286  LYS I N   1 
ATOM   4676 C CA  . LYS C 3  294 ? -1.152  -7.563  -17.346 1.00 34.87 ? 286  LYS I CA  1 
ATOM   4677 C C   . LYS C 3  294 ? -0.087  -7.961  -16.338 1.00 35.15 ? 286  LYS I C   1 
ATOM   4678 O O   . LYS C 3  294 ? 0.997   -8.387  -16.732 1.00 35.46 ? 286  LYS I O   1 
ATOM   4679 C CB  . LYS C 3  294 ? -1.614  -8.793  -18.129 1.00 36.48 ? 286  LYS I CB  1 
ATOM   4680 C CG  . LYS C 3  294 ? -2.337  -9.830  -17.283 1.00 37.58 ? 286  LYS I CG  1 
ATOM   4681 C CD  . LYS C 3  294 ? -2.715  -11.051 -18.106 1.00 38.86 ? 286  LYS I CD  1 
ATOM   4682 N N   . PHE C 3  295 ? -0.368  -7.827  -15.046 1.00 35.49 ? 287  PHE I N   1 
ATOM   4683 C CA  . PHE C 3  295 ? 0.660   -8.154  -14.068 1.00 34.93 ? 287  PHE I CA  1 
ATOM   4684 C C   . PHE C 3  295 ? 0.178   -8.286  -12.633 1.00 35.35 ? 287  PHE I C   1 
ATOM   4685 O O   . PHE C 3  295 ? -0.960  -7.958  -12.301 1.00 35.19 ? 287  PHE I O   1 
ATOM   4686 C CB  . PHE C 3  295 ? 1.740   -7.074  -14.117 1.00 34.94 ? 287  PHE I CB  1 
ATOM   4687 C CG  . PHE C 3  295 ? 1.243   -5.713  -13.707 1.00 34.21 ? 287  PHE I CG  1 
ATOM   4688 C CD1 . PHE C 3  295 ? 1.317   -5.298  -12.380 1.00 34.00 ? 287  PHE I CD1 1 
ATOM   4689 C CD2 . PHE C 3  295 ? 0.649   -4.868  -14.638 1.00 34.76 ? 287  PHE I CD2 1 
ATOM   4690 C CE1 . PHE C 3  295 ? 0.803   -4.061  -11.987 1.00 34.18 ? 287  PHE I CE1 1 
ATOM   4691 C CE2 . PHE C 3  295 ? 0.132   -3.630  -14.255 1.00 34.45 ? 287  PHE I CE2 1 
ATOM   4692 C CZ  . PHE C 3  295 ? 0.209   -3.226  -12.926 1.00 34.26 ? 287  PHE I CZ  1 
ATOM   4693 N N   . SER C 3  296 ? 1.082   -8.773  -11.791 1.00 36.18 ? 288  SER I N   1 
ATOM   4694 C CA  . SER C 3  296 ? 0.844   -8.930  -10.365 1.00 36.49 ? 288  SER I CA  1 
ATOM   4695 C C   . SER C 3  296 ? 1.977   -8.141  -9.726  1.00 35.41 ? 288  SER I C   1 
ATOM   4696 O O   . SER C 3  296 ? 3.142   -8.344  -10.059 1.00 35.65 ? 288  SER I O   1 
ATOM   4697 C CB  . SER C 3  296 ? 0.932   -10.401 -9.954  1.00 38.13 ? 288  SER I CB  1 
ATOM   4698 O OG  . SER C 3  296 ? -0.095  -11.163 -10.567 1.00 40.60 ? 288  SER I OG  1 
ATOM   4699 N N   . ILE C 3  297 ? 1.640   -7.226  -8.827  1.00 34.11 ? 289  ILE I N   1 
ATOM   4700 C CA  . ILE C 3  297 ? 2.657   -6.415  -8.180  1.00 32.35 ? 289  ILE I CA  1 
ATOM   4701 C C   . ILE C 3  297 ? 2.530   -6.508  -6.666  1.00 32.52 ? 289  ILE I C   1 
ATOM   4702 O O   . ILE C 3  297 ? 1.428   -6.486  -6.119  1.00 32.36 ? 289  ILE I O   1 
ATOM   4703 C CB  . ILE C 3  297 ? 2.541   -4.937  -8.621  1.00 32.35 ? 289  ILE I CB  1 
ATOM   4704 C CG1 . ILE C 3  297 ? 3.670   -4.113  -8.003  1.00 32.62 ? 289  ILE I CG1 1 
ATOM   4705 C CG2 . ILE C 3  297 ? 1.175   -4.382  -8.235  1.00 30.71 ? 289  ILE I CG2 1 
ATOM   4706 C CD1 . ILE C 3  297 ? 3.683   -2.662  -8.445  1.00 32.19 ? 289  ILE I CD1 1 
ATOM   4707 N N   . GLU C 3  298 ? 3.665   -6.631  -5.991  1.00 32.75 ? 290  GLU I N   1 
ATOM   4708 C CA  . GLU C 3  298 ? 3.656   -6.724  -4.543  1.00 32.85 ? 290  GLU I CA  1 
ATOM   4709 C C   . GLU C 3  298 ? 4.764   -5.880  -3.939  1.00 31.55 ? 290  GLU I C   1 
ATOM   4710 O O   . GLU C 3  298 ? 5.760   -5.571  -4.593  1.00 31.79 ? 290  GLU I O   1 
ATOM   4711 C CB  . GLU C 3  298 ? 3.822   -8.180  -4.098  1.00 35.01 ? 290  GLU I CB  1 
ATOM   4712 C CG  . GLU C 3  298 ? 5.204   -8.757  -4.340  1.00 39.05 ? 290  GLU I CG  1 
ATOM   4713 C CD  . GLU C 3  298 ? 5.389   -10.106 -3.672  1.00 41.60 ? 290  GLU I CD  1 
ATOM   4714 O OE1 . GLU C 3  298 ? 4.686   -11.065 -4.054  1.00 43.91 ? 290  GLU I OE1 1 
ATOM   4715 O OE2 . GLU C 3  298 ? 6.236   -10.207 -2.758  1.00 43.77 ? 290  GLU I OE2 1 
ATOM   4716 N N   . GLY C 3  299 ? 4.570   -5.505  -2.682  1.00 29.58 ? 291  GLY I N   1 
ATOM   4717 C CA  . GLY C 3  299 ? 5.556   -4.715  -1.978  1.00 29.17 ? 291  GLY I CA  1 
ATOM   4718 C C   . GLY C 3  299 ? 5.570   -5.165  -0.531  1.00 28.45 ? 291  GLY I C   1 
ATOM   4719 O O   . GLY C 3  299 ? 4.511   -5.329  0.073   1.00 28.06 ? 291  GLY I O   1 
ATOM   4720 N N   . SER C 3  300 ? 6.763   -5.390  0.011   1.00 28.65 ? 292  SER I N   1 
ATOM   4721 C CA  . SER C 3  300 ? 6.923   -5.813  1.404   1.00 27.75 ? 292  SER I CA  1 
ATOM   4722 C C   . SER C 3  300 ? 7.885   -4.836  2.060   1.00 26.85 ? 292  SER I C   1 
ATOM   4723 O O   . SER C 3  300 ? 8.996   -4.636  1.570   1.00 26.42 ? 292  SER I O   1 
ATOM   4724 C CB  . SER C 3  300 ? 7.500   -7.228  1.480   1.00 29.35 ? 292  SER I CB  1 
ATOM   4725 O OG  . SER C 3  300 ? 6.618   -8.171  0.901   1.00 34.03 ? 292  SER I OG  1 
ATOM   4726 N N   . TYR C 3  301 ? 7.473   -4.231  3.170   1.00 25.55 ? 293  TYR I N   1 
ATOM   4727 C CA  . TYR C 3  301 ? 8.339   -3.264  3.825   1.00 26.06 ? 293  TYR I CA  1 
ATOM   4728 C C   . TYR C 3  301 ? 8.474   -3.375  5.333   1.00 26.06 ? 293  TYR I C   1 
ATOM   4729 O O   . TYR C 3  301 ? 7.524   -3.718  6.033   1.00 25.73 ? 293  TYR I O   1 
ATOM   4730 C CB  . TYR C 3  301 ? 7.878   -1.849  3.488   1.00 25.88 ? 293  TYR I CB  1 
ATOM   4731 C CG  . TYR C 3  301 ? 7.733   -1.619  2.007   1.00 27.14 ? 293  TYR I CG  1 
ATOM   4732 C CD1 . TYR C 3  301 ? 6.522   -1.867  1.359   1.00 28.21 ? 293  TYR I CD1 1 
ATOM   4733 C CD2 . TYR C 3  301 ? 8.822   -1.209  1.241   1.00 28.66 ? 293  TYR I CD2 1 
ATOM   4734 C CE1 . TYR C 3  301 ? 6.402   -1.712  -0.019  1.00 28.29 ? 293  TYR I CE1 1 
ATOM   4735 C CE2 . TYR C 3  301 ? 8.713   -1.054  -0.133  1.00 29.06 ? 293  TYR I CE2 1 
ATOM   4736 C CZ  . TYR C 3  301 ? 7.503   -1.307  -0.756  1.00 28.75 ? 293  TYR I CZ  1 
ATOM   4737 O OH  . TYR C 3  301 ? 7.403   -1.166  -2.119  1.00 29.20 ? 293  TYR I OH  1 
ATOM   4738 N N   . GLN C 3  302 ? 9.678   -3.075  5.808   1.00 27.20 ? 294  GLN I N   1 
ATOM   4739 C CA  . GLN C 3  302 ? 9.993   -3.059  7.231   1.00 27.70 ? 294  GLN I CA  1 
ATOM   4740 C C   . GLN C 3  302 ? 9.875   -1.573  7.549   1.00 27.22 ? 294  GLN I C   1 
ATOM   4741 O O   . GLN C 3  302 ? 10.851  -0.825  7.449   1.00 27.62 ? 294  GLN I O   1 
ATOM   4742 C CB  . GLN C 3  302 ? 11.431  -3.525  7.470   1.00 30.75 ? 294  GLN I CB  1 
ATOM   4743 C CG  . GLN C 3  302 ? 11.755  -4.883  6.870   1.00 34.81 ? 294  GLN I CG  1 
ATOM   4744 C CD  . GLN C 3  302 ? 11.114  -6.027  7.623   1.00 37.98 ? 294  GLN I CD  1 
ATOM   4745 O OE1 . GLN C 3  302 ? 11.076  -7.160  7.139   1.00 41.04 ? 294  GLN I OE1 1 
ATOM   4746 N NE2 . GLN C 3  302 ? 10.619  -5.744  8.822   1.00 40.72 ? 294  GLN I NE2 1 
ATOM   4747 N N   . LEU C 3  303 ? 8.669   -1.146  7.905   1.00 24.96 ? 295  LEU I N   1 
ATOM   4748 C CA  . LEU C 3  303 ? 8.408   0.256   8.194   1.00 25.80 ? 295  LEU I CA  1 
ATOM   4749 C C   . LEU C 3  303 ? 9.230   0.855   9.329   1.00 25.99 ? 295  LEU I C   1 
ATOM   4750 O O   . LEU C 3  303 ? 9.373   2.074   9.410   1.00 26.36 ? 295  LEU I O   1 
ATOM   4751 C CB  . LEU C 3  303 ? 6.915   0.459   8.463   1.00 25.74 ? 295  LEU I CB  1 
ATOM   4752 C CG  . LEU C 3  303 ? 5.994   0.128   7.284   1.00 26.79 ? 295  LEU I CG  1 
ATOM   4753 C CD1 . LEU C 3  303 ? 4.547   0.330   7.698   1.00 26.10 ? 295  LEU I CD1 1 
ATOM   4754 C CD2 . LEU C 3  303 ? 6.340   1.012   6.086   1.00 26.39 ? 295  LEU I CD2 1 
ATOM   4755 N N   . GLU C 3  304 ? 9.775   0.015   10.204  1.00 27.33 ? 296  GLU I N   1 
ATOM   4756 C CA  . GLU C 3  304 ? 10.575  0.539   11.306  1.00 28.57 ? 296  GLU I CA  1 
ATOM   4757 C C   . GLU C 3  304 ? 11.858  1.158   10.758  1.00 30.13 ? 296  GLU I C   1 
ATOM   4758 O O   . GLU C 3  304 ? 12.497  1.979   11.420  1.00 30.06 ? 296  GLU I O   1 
ATOM   4759 C CB  . GLU C 3  304 ? 10.917  -0.565  12.315  1.00 27.61 ? 296  GLU I CB  1 
ATOM   4760 C CG  . GLU C 3  304 ? 11.904  -1.621  11.832  1.00 26.11 ? 296  GLU I CG  1 
ATOM   4761 C CD  . GLU C 3  304 ? 11.251  -2.746  11.059  1.00 26.07 ? 296  GLU I CD  1 
ATOM   4762 O OE1 . GLU C 3  304 ? 11.952  -3.731  10.749  1.00 26.91 ? 296  GLU I OE1 1 
ATOM   4763 O OE2 . GLU C 3  304 ? 10.042  -2.654  10.757  1.00 26.68 ? 296  GLU I OE2 1 
ATOM   4764 N N   . LYS C 3  305 ? 12.216  0.771   9.537   1.00 30.66 ? 297  LYS I N   1 
ATOM   4765 C CA  . LYS C 3  305 ? 13.423  1.272   8.888   1.00 33.29 ? 297  LYS I CA  1 
ATOM   4766 C C   . LYS C 3  305 ? 13.212  2.560   8.094   1.00 33.04 ? 297  LYS I C   1 
ATOM   4767 O O   . LYS C 3  305 ? 14.180  3.206   7.693   1.00 34.43 ? 297  LYS I O   1 
ATOM   4768 C CB  . LYS C 3  305 ? 13.996  0.207   7.950   1.00 34.40 ? 297  LYS I CB  1 
ATOM   4769 C CG  . LYS C 3  305 ? 14.446  -1.071  8.633   1.00 37.32 ? 297  LYS I CG  1 
ATOM   4770 C CD  . LYS C 3  305 ? 14.975  -2.057  7.605   1.00 39.90 ? 297  LYS I CD  1 
ATOM   4771 C CE  . LYS C 3  305 ? 15.500  -3.326  8.252   1.00 41.83 ? 297  LYS I CE  1 
ATOM   4772 N NZ  . LYS C 3  305 ? 16.032  -4.275  7.231   1.00 43.95 ? 297  LYS I NZ  1 
ATOM   4773 N N   . VAL C 3  306 ? 11.960  2.940   7.861   1.00 32.27 ? 298  VAL I N   1 
ATOM   4774 C CA  . VAL C 3  306 ? 11.690  4.150   7.093   1.00 31.51 ? 298  VAL I CA  1 
ATOM   4775 C C   . VAL C 3  306 ? 10.881  5.210   7.833   1.00 30.47 ? 298  VAL I C   1 
ATOM   4776 O O   . VAL C 3  306 ? 11.145  6.404   7.696   1.00 30.90 ? 298  VAL I O   1 
ATOM   4777 C CB  . VAL C 3  306 ? 10.965  3.812   5.770   1.00 31.69 ? 298  VAL I CB  1 
ATOM   4778 C CG1 . VAL C 3  306 ? 11.820  2.869   4.939   1.00 34.12 ? 298  VAL I CG1 1 
ATOM   4779 C CG2 . VAL C 3  306 ? 9.619   3.181   6.056   1.00 31.73 ? 298  VAL I CG2 1 
ATOM   4780 N N   . LEU C 3  307 ? 9.899   4.779   8.616   1.00 29.24 ? 299  LEU I N   1 
ATOM   4781 C CA  . LEU C 3  307 ? 9.060   5.718   9.351   1.00 29.48 ? 299  LEU I CA  1 
ATOM   4782 C C   . LEU C 3  307 ? 9.813   6.683   10.266  1.00 30.02 ? 299  LEU I C   1 
ATOM   4783 O O   . LEU C 3  307 ? 9.407   7.833   10.419  1.00 29.33 ? 299  LEU I O   1 
ATOM   4784 C CB  . LEU C 3  307 ? 7.997   4.962   10.153  1.00 28.38 ? 299  LEU I CB  1 
ATOM   4785 C CG  . LEU C 3  307 ? 6.935   4.259   9.301   1.00 29.54 ? 299  LEU I CG  1 
ATOM   4786 C CD1 . LEU C 3  307 ? 5.832   3.723   10.196  1.00 27.59 ? 299  LEU I CD1 1 
ATOM   4787 C CD2 . LEU C 3  307 ? 6.354   5.239   8.293   1.00 29.05 ? 299  LEU I CD2 1 
ATOM   4788 N N   . PRO C 3  308 ? 10.916  6.233   10.892  1.00 32.04 ? 300  PRO I N   1 
ATOM   4789 C CA  . PRO C 3  308 ? 11.651  7.149   11.771  1.00 32.37 ? 300  PRO I CA  1 
ATOM   4790 C C   . PRO C 3  308 ? 12.067  8.437   11.059  1.00 33.92 ? 300  PRO I C   1 
ATOM   4791 O O   . PRO C 3  308 ? 11.961  9.528   11.621  1.00 34.39 ? 300  PRO I O   1 
ATOM   4792 C CB  . PRO C 3  308 ? 12.849  6.312   12.210  1.00 32.30 ? 300  PRO I CB  1 
ATOM   4793 C CG  . PRO C 3  308 ? 12.275  4.928   12.261  1.00 32.66 ? 300  PRO I CG  1 
ATOM   4794 C CD  . PRO C 3  308 ? 11.470  4.869   10.978  1.00 31.43 ? 300  PRO I CD  1 
ATOM   4795 N N   . SER C 3  309 ? 12.531  8.307   9.819   1.00 34.77 ? 301  SER I N   1 
ATOM   4796 C CA  . SER C 3  309 ? 12.962  9.466   9.043   1.00 36.73 ? 301  SER I CA  1 
ATOM   4797 C C   . SER C 3  309 ? 11.790  10.381  8.695   1.00 37.34 ? 301  SER I C   1 
ATOM   4798 O O   . SER C 3  309 ? 11.986  11.512  8.247   1.00 38.13 ? 301  SER I O   1 
ATOM   4799 C CB  . SER C 3  309 ? 13.666  9.017   7.756   1.00 37.16 ? 301  SER I CB  1 
ATOM   4800 O OG  . SER C 3  309 ? 12.784  8.306   6.903   1.00 38.90 ? 301  SER I OG  1 
ATOM   4801 N N   . LEU C 3  310 ? 10.572  9.890   8.904   1.00 36.77 ? 302  LEU I N   1 
ATOM   4802 C CA  . LEU C 3  310 ? 9.375   10.669  8.613   1.00 36.51 ? 302  LEU I CA  1 
ATOM   4803 C C   . LEU C 3  310 ? 8.768   11.286  9.869   1.00 36.77 ? 302  LEU I C   1 
ATOM   4804 O O   . LEU C 3  310 ? 7.722   11.936  9.804   1.00 36.95 ? 302  LEU I O   1 
ATOM   4805 C CB  . LEU C 3  310 ? 8.330   9.797   7.914   1.00 37.23 ? 302  LEU I CB  1 
ATOM   4806 C CG  . LEU C 3  310 ? 8.737   9.215   6.559   1.00 37.79 ? 302  LEU I CG  1 
ATOM   4807 C CD1 . LEU C 3  310 ? 7.569   8.442   5.972   1.00 37.79 ? 302  LEU I CD1 1 
ATOM   4808 C CD2 . LEU C 3  310 ? 9.159   10.337  5.619   1.00 38.02 ? 302  LEU I CD2 1 
ATOM   4809 N N   . GLY C 3  311 ? 9.420   11.080  11.011  1.00 35.76 ? 303  GLY I N   1 
ATOM   4810 C CA  . GLY C 3  311 ? 8.920   11.645  12.252  1.00 35.28 ? 303  GLY I CA  1 
ATOM   4811 C C   . GLY C 3  311 ? 8.437   10.640  13.283  1.00 35.29 ? 303  GLY I C   1 
ATOM   4812 O O   . GLY C 3  311 ? 8.338   10.960  14.465  1.00 35.44 ? 303  GLY I O   1 
ATOM   4813 N N   . ILE C 3  312 ? 8.132   9.425   12.843  1.00 34.04 ? 304  ILE I N   1 
ATOM   4814 C CA  . ILE C 3  312 ? 7.656   8.387   13.751  1.00 33.46 ? 304  ILE I CA  1 
ATOM   4815 C C   . ILE C 3  312 ? 8.834   7.483   14.103  1.00 32.55 ? 304  ILE I C   1 
ATOM   4816 O O   . ILE C 3  312 ? 9.096   6.495   13.418  1.00 31.60 ? 304  ILE I O   1 
ATOM   4817 C CB  . ILE C 3  312 ? 6.542   7.555   13.088  1.00 34.64 ? 304  ILE I CB  1 
ATOM   4818 C CG1 . ILE C 3  312 ? 5.458   8.490   12.541  1.00 35.51 ? 304  ILE I CG1 1 
ATOM   4819 C CG2 . ILE C 3  312 ? 5.941   6.594   14.096  1.00 34.04 ? 304  ILE I CG2 1 
ATOM   4820 C CD1 . ILE C 3  312 ? 4.360   7.784   11.762  1.00 36.30 ? 304  ILE I CD1 1 
ATOM   4821 N N   . SER C 3  313 ? 9.535   7.821   15.181  1.00 31.92 ? 305  SER I N   1 
ATOM   4822 C CA  . SER C 3  313 ? 10.713  7.062   15.592  1.00 32.12 ? 305  SER I CA  1 
ATOM   4823 C C   . SER C 3  313 ? 10.663  6.400   16.969  1.00 31.62 ? 305  SER I C   1 
ATOM   4824 O O   . SER C 3  313 ? 11.049  5.241   17.115  1.00 30.82 ? 305  SER I O   1 
ATOM   4825 C CB  . SER C 3  313 ? 11.939  7.973   15.521  1.00 32.56 ? 305  SER I CB  1 
ATOM   4826 O OG  . SER C 3  313 ? 11.692  9.186   16.212  1.00 35.25 ? 305  SER I OG  1 
ATOM   4827 N N   . ASN C 3  314 ? 10.203  7.141   17.971  1.00 31.74 ? 306  ASN I N   1 
ATOM   4828 C CA  . ASN C 3  314 ? 10.126  6.643   19.345  1.00 31.96 ? 306  ASN I CA  1 
ATOM   4829 C C   . ASN C 3  314 ? 9.610   5.214   19.513  1.00 30.96 ? 306  ASN I C   1 
ATOM   4830 O O   . ASN C 3  314 ? 10.245  4.392   20.180  1.00 29.96 ? 306  ASN I O   1 
ATOM   4831 C CB  . ASN C 3  314 ? 9.268   7.593   20.184  1.00 33.77 ? 306  ASN I CB  1 
ATOM   4832 C CG  . ASN C 3  314 ? 9.954   8.919   20.448  1.00 34.50 ? 306  ASN I CG  1 
ATOM   4833 O OD1 . ASN C 3  314 ? 10.735  9.402   19.629  1.00 37.52 ? 306  ASN I OD1 1 
ATOM   4834 N ND2 . ASN C 3  314 ? 9.652   9.522   21.589  1.00 37.81 ? 306  ASN I ND2 1 
ATOM   4835 N N   . VAL C 3  315 ? 8.461   4.921   18.913  1.00 29.40 ? 307  VAL I N   1 
ATOM   4836 C CA  . VAL C 3  315 ? 7.847   3.600   19.020  1.00 27.63 ? 307  VAL I CA  1 
ATOM   4837 C C   . VAL C 3  315 ? 8.754   2.450   18.583  1.00 27.51 ? 307  VAL I C   1 
ATOM   4838 O O   . VAL C 3  315 ? 8.510   1.294   18.927  1.00 26.53 ? 307  VAL I O   1 
ATOM   4839 C CB  . VAL C 3  315 ? 6.526   3.541   18.206  1.00 28.27 ? 307  VAL I CB  1 
ATOM   4840 C CG1 . VAL C 3  315 ? 6.816   3.709   16.719  1.00 28.70 ? 307  VAL I CG1 1 
ATOM   4841 C CG2 . VAL C 3  315 ? 5.802   2.229   18.471  1.00 29.43 ? 307  VAL I CG2 1 
ATOM   4842 N N   . PHE C 3  316 ? 9.804   2.762   17.832  1.00 27.92 ? 308  PHE I N   1 
ATOM   4843 C CA  . PHE C 3  316 ? 10.722  1.732   17.358  1.00 28.90 ? 308  PHE I CA  1 
ATOM   4844 C C   . PHE C 3  316 ? 12.024  1.702   18.151  1.00 30.88 ? 308  PHE I C   1 
ATOM   4845 O O   . PHE C 3  316 ? 12.979  1.036   17.754  1.00 31.70 ? 308  PHE I O   1 
ATOM   4846 C CB  . PHE C 3  316 ? 11.037  1.957   15.877  1.00 27.83 ? 308  PHE I CB  1 
ATOM   4847 C CG  . PHE C 3  316 ? 9.819   2.002   15.002  1.00 26.87 ? 308  PHE I CG  1 
ATOM   4848 C CD1 . PHE C 3  316 ? 9.033   0.871   14.825  1.00 26.80 ? 308  PHE I CD1 1 
ATOM   4849 C CD2 . PHE C 3  316 ? 9.448   3.184   14.368  1.00 27.87 ? 308  PHE I CD2 1 
ATOM   4850 C CE1 . PHE C 3  316 ? 7.893   0.914   14.030  1.00 26.84 ? 308  PHE I CE1 1 
ATOM   4851 C CE2 . PHE C 3  316 ? 8.311   3.238   13.571  1.00 26.86 ? 308  PHE I CE2 1 
ATOM   4852 C CZ  . PHE C 3  316 ? 7.531   2.101   13.402  1.00 27.59 ? 308  PHE I CZ  1 
ATOM   4853 N N   . THR C 3  317 ? 12.061  2.417   19.271  1.00 32.67 ? 309  THR I N   1 
ATOM   4854 C CA  . THR C 3  317 ? 13.264  2.470   20.100  1.00 34.08 ? 309  THR I CA  1 
ATOM   4855 C C   . THR C 3  317 ? 13.015  1.970   21.517  1.00 34.98 ? 309  THR I C   1 
ATOM   4856 O O   . THR C 3  317 ? 11.877  1.699   21.903  1.00 34.66 ? 309  THR I O   1 
ATOM   4857 C CB  . THR C 3  317 ? 13.802  3.901   20.215  1.00 34.63 ? 309  THR I CB  1 
ATOM   4858 O OG1 . THR C 3  317 ? 12.897  4.683   21.004  1.00 34.32 ? 309  THR I OG1 1 
ATOM   4859 C CG2 . THR C 3  317 ? 13.948  4.532   18.837  1.00 34.83 ? 309  THR I CG2 1 
ATOM   4860 N N   . SER C 3  318 ? 14.093  1.864   22.291  1.00 35.46 ? 310  SER I N   1 
ATOM   4861 C CA  . SER C 3  318 ? 14.009  1.399   23.669  1.00 36.06 ? 310  SER I CA  1 
ATOM   4862 C C   . SER C 3  318 ? 13.357  2.435   24.583  1.00 36.20 ? 310  SER I C   1 
ATOM   4863 O O   . SER C 3  318 ? 12.984  2.121   25.713  1.00 37.78 ? 310  SER I O   1 
ATOM   4864 C CB  . SER C 3  318 ? 15.403  1.047   24.196  1.00 36.31 ? 310  SER I CB  1 
ATOM   4865 O OG  . SER C 3  318 ? 16.261  2.173   24.163  1.00 38.01 ? 310  SER I OG  1 
ATOM   4866 N N   . HIS C 3  319 ? 13.229  3.671   24.107  1.00 35.68 ? 311  HIS I N   1 
ATOM   4867 C CA  . HIS C 3  319 ? 12.590  4.702   24.914  1.00 36.12 ? 311  HIS I CA  1 
ATOM   4868 C C   . HIS C 3  319 ? 11.167  4.933   24.424  1.00 35.77 ? 311  HIS I C   1 
ATOM   4869 O O   . HIS C 3  319 ? 10.595  6.009   24.597  1.00 35.36 ? 311  HIS I O   1 
ATOM   4870 C CB  . HIS C 3  319 ? 13.388  6.015   24.893  1.00 38.55 ? 311  HIS I CB  1 
ATOM   4871 C CG  . HIS C 3  319 ? 13.551  6.620   23.533  1.00 40.59 ? 311  HIS I CG  1 
ATOM   4872 N ND1 . HIS C 3  319 ? 14.515  6.203   22.641  1.00 41.87 ? 311  HIS I ND1 1 
ATOM   4873 C CD2 . HIS C 3  319 ? 12.894  7.638   22.928  1.00 42.00 ? 311  HIS I CD2 1 
ATOM   4874 C CE1 . HIS C 3  319 ? 14.448  6.941   21.546  1.00 42.83 ? 311  HIS I CE1 1 
ATOM   4875 N NE2 . HIS C 3  319 ? 13.472  7.819   21.695  1.00 42.70 ? 311  HIS I NE2 1 
ATOM   4876 N N   . ALA C 3  320 ? 10.602  3.900   23.810  1.00 34.62 ? 312  ALA I N   1 
ATOM   4877 C CA  . ALA C 3  320 ? 9.242   3.959   23.299  1.00 33.91 ? 312  ALA I CA  1 
ATOM   4878 C C   . ALA C 3  320 ? 8.261   3.920   24.461  1.00 33.59 ? 312  ALA I C   1 
ATOM   4879 O O   . ALA C 3  320 ? 8.437   3.152   25.409  1.00 34.25 ? 312  ALA I O   1 
ATOM   4880 C CB  . ALA C 3  320 ? 8.986   2.782   22.373  1.00 33.71 ? 312  ALA I CB  1 
ATOM   4881 N N   . ASP C 3  321 ? 7.236   4.759   24.402  1.00 31.44 ? 313  ASP I N   1 
ATOM   4882 C CA  . ASP C 3  321 ? 6.235   4.765   25.454  1.00 31.60 ? 313  ASP I CA  1 
ATOM   4883 C C   . ASP C 3  321 ? 5.040   3.969   24.956  1.00 30.07 ? 313  ASP I C   1 
ATOM   4884 O O   . ASP C 3  321 ? 4.153   4.508   24.292  1.00 30.67 ? 313  ASP I O   1 
ATOM   4885 C CB  . ASP C 3  321 ? 5.798   6.190   25.797  1.00 31.89 ? 313  ASP I CB  1 
ATOM   4886 C CG  . ASP C 3  321 ? 4.758   6.228   26.904  1.00 32.23 ? 313  ASP I CG  1 
ATOM   4887 O OD1 . ASP C 3  321 ? 4.250   5.153   27.286  1.00 32.68 ? 313  ASP I OD1 1 
ATOM   4888 O OD2 . ASP C 3  321 ? 4.440   7.334   27.388  1.00 34.39 ? 313  ASP I OD2 1 
ATOM   4889 N N   . LEU C 3  322 ? 5.037   2.678   25.264  1.00 28.65 ? 314  LEU I N   1 
ATOM   4890 C CA  . LEU C 3  322 ? 3.954   1.791   24.868  1.00 26.31 ? 314  LEU I CA  1 
ATOM   4891 C C   . LEU C 3  322 ? 3.292   1.260   26.127  1.00 25.69 ? 314  LEU I C   1 
ATOM   4892 O O   . LEU C 3  322 ? 2.908   0.091   26.202  1.00 24.84 ? 314  LEU I O   1 
ATOM   4893 C CB  . LEU C 3  322 ? 4.493   0.634   24.023  1.00 26.05 ? 314  LEU I CB  1 
ATOM   4894 C CG  . LEU C 3  322 ? 4.924   1.036   22.609  1.00 27.47 ? 314  LEU I CG  1 
ATOM   4895 C CD1 . LEU C 3  322 ? 5.555   -0.144  21.892  1.00 27.52 ? 314  LEU I CD1 1 
ATOM   4896 C CD2 . LEU C 3  322 ? 3.707   1.543   21.850  1.00 27.32 ? 314  LEU I CD2 1 
ATOM   4897 N N   . SER C 3  323 ? 3.163   2.144   27.113  1.00 25.81 ? 315  SER I N   1 
ATOM   4898 C CA  . SER C 3  323 ? 2.555   1.800   28.391  1.00 26.16 ? 315  SER I CA  1 
ATOM   4899 C C   . SER C 3  323 ? 1.128   1.305   28.207  1.00 25.89 ? 315  SER I C   1 
ATOM   4900 O O   . SER C 3  323 ? 0.590   0.608   29.064  1.00 24.90 ? 315  SER I O   1 
ATOM   4901 C CB  . SER C 3  323 ? 2.583   3.015   29.326  1.00 26.27 ? 315  SER I CB  1 
ATOM   4902 O OG  . SER C 3  323 ? 2.008   4.157   28.714  1.00 29.92 ? 315  SER I OG  1 
ATOM   4903 N N   . GLY C 3  324 ? 0.520   1.666   27.079  1.00 25.23 ? 316  GLY I N   1 
ATOM   4904 C CA  . GLY C 3  324 ? -0.837  1.232   26.803  1.00 24.93 ? 316  GLY I CA  1 
ATOM   4905 C C   . GLY C 3  324 ? -0.879  -0.234  26.420  1.00 24.41 ? 316  GLY I C   1 
ATOM   4906 O O   . GLY C 3  324 ? -1.876  -0.915  26.639  1.00 26.47 ? 316  GLY I O   1 
ATOM   4907 N N   . ILE C 3  325 ? 0.212   -0.728  25.847  1.00 23.69 ? 317  ILE I N   1 
ATOM   4908 C CA  . ILE C 3  325 ? 0.282   -2.125  25.436  1.00 24.08 ? 317  ILE I CA  1 
ATOM   4909 C C   . ILE C 3  325 ? 0.702   -3.054  26.572  1.00 24.10 ? 317  ILE I C   1 
ATOM   4910 O O   . ILE C 3  325 ? 0.150   -4.140  26.729  1.00 23.27 ? 317  ILE I O   1 
ATOM   4911 C CB  . ILE C 3  325 ? 1.290   -2.322  24.281  1.00 24.30 ? 317  ILE I CB  1 
ATOM   4912 C CG1 . ILE C 3  325 ? 0.833   -1.541  23.050  1.00 26.09 ? 317  ILE I CG1 1 
ATOM   4913 C CG2 . ILE C 3  325 ? 1.427   -3.800  23.961  1.00 23.30 ? 317  ILE I CG2 1 
ATOM   4914 C CD1 . ILE C 3  325 ? 1.783   -1.646  21.873  1.00 26.96 ? 317  ILE I CD1 1 
ATOM   4915 N N   . SER C 3  326 ? 1.685   -2.627  27.357  1.00 23.86 ? 318  SER I N   1 
ATOM   4916 C CA  . SER C 3  326 ? 2.188   -3.453  28.451  1.00 25.15 ? 318  SER I CA  1 
ATOM   4917 C C   . SER C 3  326 ? 2.805   -2.614  29.557  1.00 25.24 ? 318  SER I C   1 
ATOM   4918 O O   . SER C 3  326 ? 3.246   -1.490  29.320  1.00 25.20 ? 318  SER I O   1 
ATOM   4919 C CB  . SER C 3  326 ? 3.238   -4.431  27.908  1.00 26.89 ? 318  SER I CB  1 
ATOM   4920 O OG  . SER C 3  326 ? 3.876   -5.146  28.951  1.00 29.26 ? 318  SER I OG  1 
ATOM   4921 N N   . ASN C 3  327 ? 2.826   -3.156  30.771  1.00 26.35 ? 319  ASN I N   1 
ATOM   4922 C CA  . ASN C 3  327 ? 3.423   -2.431  31.882  1.00 26.57 ? 319  ASN I CA  1 
ATOM   4923 C C   . ASN C 3  327 ? 4.907   -2.779  32.011  1.00 26.75 ? 319  ASN I C   1 
ATOM   4924 O O   . ASN C 3  327 ? 5.581   -2.324  32.932  1.00 25.57 ? 319  ASN I O   1 
ATOM   4925 C CB  . ASN C 3  327 ? 2.674   -2.717  33.194  1.00 28.48 ? 319  ASN I CB  1 
ATOM   4926 C CG  . ASN C 3  327 ? 2.711   -4.177  33.595  1.00 29.27 ? 319  ASN I CG  1 
ATOM   4927 O OD1 . ASN C 3  327 ? 2.081   -4.572  34.577  1.00 34.11 ? 319  ASN I OD1 1 
ATOM   4928 N ND2 . ASN C 3  327 ? 3.448   -4.986  32.847  1.00 32.15 ? 319  ASN I ND2 1 
ATOM   4929 N N   . HIS C 3  328 ? 5.410   -3.591  31.081  1.00 26.51 ? 320  HIS I N   1 
ATOM   4930 C CA  . HIS C 3  328 ? 6.830   -3.954  31.080  1.00 26.83 ? 320  HIS I CA  1 
ATOM   4931 C C   . HIS C 3  328 ? 7.606   -2.824  30.408  1.00 27.20 ? 320  HIS I C   1 
ATOM   4932 O O   . HIS C 3  328 ? 7.130   -2.230  29.445  1.00 27.12 ? 320  HIS I O   1 
ATOM   4933 C CB  . HIS C 3  328 ? 7.060   -5.269  30.335  1.00 26.36 ? 320  HIS I CB  1 
ATOM   4934 C CG  . HIS C 3  328 ? 6.652   -6.481  31.112  1.00 26.06 ? 320  HIS I CG  1 
ATOM   4935 N ND1 . HIS C 3  328 ? 6.986   -7.761  30.726  1.00 26.42 ? 320  HIS I ND1 1 
ATOM   4936 C CD2 . HIS C 3  328 ? 5.931   -6.608  32.251  1.00 26.80 ? 320  HIS I CD2 1 
ATOM   4937 C CE1 . HIS C 3  328 ? 6.488   -8.625  31.594  1.00 27.19 ? 320  HIS I CE1 1 
ATOM   4938 N NE2 . HIS C 3  328 ? 5.842   -7.950  32.528  1.00 26.79 ? 320  HIS I NE2 1 
ATOM   4939 N N   . SER C 3  329 ? 8.806   -2.542  30.907  1.00 26.86 ? 321  SER I N   1 
ATOM   4940 C CA  . SER C 3  329 ? 9.626   -1.444  30.389  1.00 27.94 ? 321  SER I CA  1 
ATOM   4941 C C   . SER C 3  329 ? 10.341  -1.623  29.048  1.00 30.68 ? 321  SER I C   1 
ATOM   4942 O O   . SER C 3  329 ? 10.517  -0.656  28.308  1.00 31.12 ? 321  SER I O   1 
ATOM   4943 C CB  . SER C 3  329 ? 10.665  -1.051  31.435  1.00 26.83 ? 321  SER I CB  1 
ATOM   4944 O OG  . SER C 3  329 ? 11.493  -2.158  31.724  1.00 25.78 ? 321  SER I OG  1 
ATOM   4945 N N   . ASN C 3  330 ? 10.767  -2.835  28.725  1.00 31.60 ? 322  ASN I N   1 
ATOM   4946 C CA  . ASN C 3  330 ? 11.475  -3.024  27.464  1.00 35.62 ? 322  ASN I CA  1 
ATOM   4947 C C   . ASN C 3  330 ? 10.570  -3.419  26.307  1.00 35.32 ? 322  ASN I C   1 
ATOM   4948 O O   . ASN C 3  330 ? 10.854  -4.363  25.570  1.00 37.47 ? 322  ASN I O   1 
ATOM   4949 C CB  . ASN C 3  330 ? 12.598  -4.046  27.645  1.00 38.75 ? 322  ASN I CB  1 
ATOM   4950 C CG  . ASN C 3  330 ? 13.796  -3.459  28.367  1.00 41.70 ? 322  ASN I CG  1 
ATOM   4951 O OD1 . ASN C 3  330 ? 13.656  -2.842  29.425  1.00 43.14 ? 322  ASN I OD1 1 
ATOM   4952 N ND2 . ASN C 3  330 ? 14.983  -3.645  27.796  1.00 43.20 ? 322  ASN I ND2 1 
ATOM   4953 N N   . ILE C 3  331 ? 9.484   -2.671  26.149  1.00 34.49 ? 323  ILE I N   1 
ATOM   4954 C CA  . ILE C 3  331 ? 8.521   -2.919  25.088  1.00 32.25 ? 323  ILE I CA  1 
ATOM   4955 C C   . ILE C 3  331 ? 8.709   -1.904  23.961  1.00 31.45 ? 323  ILE I C   1 
ATOM   4956 O O   . ILE C 3  331 ? 8.774   -0.700  24.197  1.00 30.53 ? 323  ILE I O   1 
ATOM   4957 C CB  . ILE C 3  331 ? 7.072   -2.824  25.624  1.00 33.63 ? 323  ILE I CB  1 
ATOM   4958 C CG1 . ILE C 3  331 ? 6.082   -3.201  24.524  1.00 34.87 ? 323  ILE I CG1 1 
ATOM   4959 C CG2 . ILE C 3  331 ? 6.792   -1.422  26.136  1.00 33.84 ? 323  ILE I CG2 1 
ATOM   4960 C CD1 . ILE C 3  331 ? 6.231   -4.622  24.055  1.00 37.06 ? 323  ILE I CD1 1 
ATOM   4961 N N   . GLN C 3  332 ? 8.805   -2.404  22.735  1.00 29.95 ? 324  GLN I N   1 
ATOM   4962 C CA  . GLN C 3  332 ? 8.982   -1.548  21.570  1.00 29.01 ? 324  GLN I CA  1 
ATOM   4963 C C   . GLN C 3  332 ? 8.556   -2.348  20.352  1.00 26.76 ? 324  GLN I C   1 
ATOM   4964 O O   . GLN C 3  332 ? 8.468   -3.575  20.413  1.00 24.91 ? 324  GLN I O   1 
ATOM   4965 C CB  . GLN C 3  332 ? 10.450  -1.154  21.416  1.00 31.72 ? 324  GLN I CB  1 
ATOM   4966 C CG  . GLN C 3  332 ? 11.334  -2.300  20.949  1.00 36.68 ? 324  GLN I CG  1 
ATOM   4967 C CD  . GLN C 3  332 ? 12.797  -1.917  20.853  1.00 40.12 ? 324  GLN I CD  1 
ATOM   4968 O OE1 . GLN C 3  332 ? 13.611  -2.665  20.313  1.00 44.21 ? 324  GLN I OE1 1 
ATOM   4969 N NE2 . GLN C 3  332 ? 13.140  -0.752  21.385  1.00 43.04 ? 324  GLN I NE2 1 
ATOM   4970 N N   . VAL C 3  333 ? 8.277   -1.663  19.249  1.00 25.47 ? 325  VAL I N   1 
ATOM   4971 C CA  . VAL C 3  333 ? 7.903   -2.372  18.038  1.00 24.41 ? 325  VAL I CA  1 
ATOM   4972 C C   . VAL C 3  333 ? 9.212   -2.757  17.359  1.00 22.84 ? 325  VAL I C   1 
ATOM   4973 O O   . VAL C 3  333 ? 9.931   -1.900  16.843  1.00 24.20 ? 325  VAL I O   1 
ATOM   4974 C CB  . VAL C 3  333 ? 7.056   -1.494  17.093  1.00 23.55 ? 325  VAL I CB  1 
ATOM   4975 C CG1 . VAL C 3  333 ? 6.769   -2.252  15.804  1.00 24.92 ? 325  VAL I CG1 1 
ATOM   4976 C CG2 . VAL C 3  333 ? 5.749   -1.112  17.776  1.00 23.31 ? 325  VAL I CG2 1 
ATOM   4977 N N   . SER C 3  334 ? 9.526   -4.049  17.391  1.00 22.50 ? 326  SER I N   1 
ATOM   4978 C CA  . SER C 3  334 ? 10.754  -4.565  16.803  1.00 22.24 ? 326  SER I CA  1 
ATOM   4979 C C   . SER C 3  334 ? 10.693  -4.452  15.288  1.00 23.28 ? 326  SER I C   1 
ATOM   4980 O O   . SER C 3  334 ? 11.650  -4.031  14.642  1.00 25.28 ? 326  SER I O   1 
ATOM   4981 C CB  . SER C 3  334 ? 10.949  -6.027  17.208  1.00 23.29 ? 326  SER I CB  1 
ATOM   4982 O OG  . SER C 3  334 ? 10.909  -6.167  18.622  1.00 22.48 ? 326  SER I OG  1 
ATOM   4983 N N   . GLU C 3  335 ? 9.554   -4.842  14.733  1.00 22.69 ? 327  GLU I N   1 
ATOM   4984 C CA  . GLU C 3  335 ? 9.335   -4.778  13.298  1.00 24.50 ? 327  GLU I CA  1 
ATOM   4985 C C   . GLU C 3  335 ? 7.875   -4.466  13.031  1.00 23.71 ? 327  GLU I C   1 
ATOM   4986 O O   . GLU C 3  335 ? 6.988   -4.902  13.762  1.00 22.67 ? 327  GLU I O   1 
ATOM   4987 C CB  . GLU C 3  335 ? 9.679   -6.112  12.627  1.00 26.24 ? 327  GLU I CB  1 
ATOM   4988 C CG  . GLU C 3  335 ? 11.158  -6.421  12.513  1.00 30.09 ? 327  GLU I CG  1 
ATOM   4989 C CD  . GLU C 3  335 ? 11.413  -7.726  11.781  1.00 32.70 ? 327  GLU I CD  1 
ATOM   4990 O OE1 . GLU C 3  335 ? 10.839  -7.915  10.687  1.00 33.67 ? 327  GLU I OE1 1 
ATOM   4991 O OE2 . GLU C 3  335 ? 12.187  -8.562  12.294  1.00 34.03 ? 327  GLU I OE2 1 
ATOM   4992 N N   . MET C 3  336 ? 7.639   -3.697  11.977  1.00 24.26 ? 328  MET I N   1 
ATOM   4993 C CA  . MET C 3  336 ? 6.295   -3.344  11.560  1.00 23.40 ? 328  MET I CA  1 
ATOM   4994 C C   . MET C 3  336 ? 6.311   -3.666  10.076  1.00 23.14 ? 328  MET I C   1 
ATOM   4995 O O   . MET C 3  336 ? 6.783   -2.872  9.267   1.00 23.87 ? 328  MET I O   1 
ATOM   4996 C CB  . MET C 3  336 ? 6.032   -1.859  11.783  1.00 24.69 ? 328  MET I CB  1 
ATOM   4997 C CG  . MET C 3  336 ? 4.633   -1.425  11.395  1.00 26.00 ? 328  MET I CG  1 
ATOM   4998 S SD  . MET C 3  336 ? 4.356   0.312   11.743  1.00 30.04 ? 328  MET I SD  1 
ATOM   4999 C CE  . MET C 3  336 ? 2.805   0.589   10.877  1.00 28.38 ? 328  MET I CE  1 
ATOM   5000 N N   . VAL C 3  337 ? 5.819   -4.851  9.734   1.00 23.86 ? 329  VAL I N   1 
ATOM   5001 C CA  . VAL C 3  337 ? 5.817   -5.301  8.351   1.00 26.13 ? 329  VAL I CA  1 
ATOM   5002 C C   . VAL C 3  337 ? 4.508   -5.048  7.630   1.00 25.82 ? 329  VAL I C   1 
ATOM   5003 O O   . VAL C 3  337 ? 3.431   -5.332  8.146   1.00 26.04 ? 329  VAL I O   1 
ATOM   5004 C CB  . VAL C 3  337 ? 6.143   -6.805  8.264   1.00 26.76 ? 329  VAL I CB  1 
ATOM   5005 C CG1 . VAL C 3  337 ? 6.275   -7.229  6.805   1.00 28.53 ? 329  VAL I CG1 1 
ATOM   5006 C CG2 . VAL C 3  337 ? 7.423   -7.100  9.019   1.00 26.99 ? 329  VAL I CG2 1 
ATOM   5007 N N   . HIS C 3  338 ? 4.622   -4.498  6.427   1.00 24.54 ? 330  HIS I N   1 
ATOM   5008 C CA  . HIS C 3  338 ? 3.470   -4.214  5.590   1.00 24.12 ? 330  HIS I CA  1 
ATOM   5009 C C   . HIS C 3  338 ? 3.700   -4.889  4.247   1.00 23.53 ? 330  HIS I C   1 
ATOM   5010 O O   . HIS C 3  338 ? 4.760   -4.732  3.641   1.00 24.72 ? 330  HIS I O   1 
ATOM   5011 C CB  . HIS C 3  338 ? 3.312   -2.705  5.376   1.00 24.34 ? 330  HIS I CB  1 
ATOM   5012 C CG  . HIS C 3  338 ? 2.267   -2.345  4.364   1.00 24.55 ? 330  HIS I CG  1 
ATOM   5013 N ND1 . HIS C 3  338 ? 0.921   -2.564  4.571   1.00 25.14 ? 330  HIS I ND1 1 
ATOM   5014 C CD2 . HIS C 3  338 ? 2.374   -1.810  3.123   1.00 24.49 ? 330  HIS I CD2 1 
ATOM   5015 C CE1 . HIS C 3  338 ? 0.245   -2.181  3.501   1.00 27.20 ? 330  HIS I CE1 1 
ATOM   5016 N NE2 . HIS C 3  338 ? 1.103   -1.721  2.608   1.00 23.45 ? 330  HIS I NE2 1 
ATOM   5017 N N   . LYS C 3  339 ? 2.718   -5.659  3.797   1.00 24.80 ? 331  LYS I N   1 
ATOM   5018 C CA  . LYS C 3  339 ? 2.820   -6.321  2.508   1.00 26.37 ? 331  LYS I CA  1 
ATOM   5019 C C   . LYS C 3  339 ? 1.536   -6.098  1.728   1.00 25.79 ? 331  LYS I C   1 
ATOM   5020 O O   . LYS C 3  339 ? 0.444   -6.387  2.214   1.00 25.73 ? 331  LYS I O   1 
ATOM   5021 C CB  . LYS C 3  339 ? 3.074   -7.822  2.665   1.00 27.43 ? 331  LYS I CB  1 
ATOM   5022 C CG  . LYS C 3  339 ? 3.293   -8.516  1.323   1.00 29.19 ? 331  LYS I CG  1 
ATOM   5023 C CD  . LYS C 3  339 ? 3.817   -9.934  1.471   1.00 32.87 ? 331  LYS I CD  1 
ATOM   5024 C CE  . LYS C 3  339 ? 4.165   -10.524 0.105   1.00 34.35 ? 331  LYS I CE  1 
ATOM   5025 N NZ  . LYS C 3  339 ? 4.771   -11.885 0.202   1.00 36.77 ? 331  LYS I NZ  1 
ATOM   5026 N N   . ALA C 3  340 ? 1.680   -5.562  0.522   1.00 25.67 ? 332  ALA I N   1 
ATOM   5027 C CA  . ALA C 3  340 ? 0.544   -5.291  -0.348  1.00 25.80 ? 332  ALA I CA  1 
ATOM   5028 C C   . ALA C 3  340 ? 0.741   -6.039  -1.659  1.00 25.36 ? 332  ALA I C   1 
ATOM   5029 O O   . ALA C 3  340 ? 1.833   -6.028  -2.228  1.00 24.30 ? 332  ALA I O   1 
ATOM   5030 C CB  . ALA C 3  340 ? 0.432   -3.799  -0.611  1.00 24.38 ? 332  ALA I CB  1 
ATOM   5031 N N   . VAL C 3  341 ? -0.317  -6.697  -2.119  1.00 26.89 ? 333  VAL I N   1 
ATOM   5032 C CA  . VAL C 3  341 ? -0.284  -7.460  -3.359  1.00 28.84 ? 333  VAL I CA  1 
ATOM   5033 C C   . VAL C 3  341 ? -1.545  -7.182  -4.171  1.00 28.83 ? 333  VAL I C   1 
ATOM   5034 O O   . VAL C 3  341 ? -2.660  -7.300  -3.665  1.00 28.92 ? 333  VAL I O   1 
ATOM   5035 C CB  . VAL C 3  341 ? -0.210  -8.978  -3.083  1.00 29.31 ? 333  VAL I CB  1 
ATOM   5036 C CG1 . VAL C 3  341 ? -0.245  -9.752  -4.396  1.00 29.48 ? 333  VAL I CG1 1 
ATOM   5037 C CG2 . VAL C 3  341 ? 1.057   -9.305  -2.311  1.00 29.76 ? 333  VAL I CG2 1 
ATOM   5038 N N   . VAL C 3  342 ? -1.361  -6.798  -5.428  1.00 29.50 ? 334  VAL I N   1 
ATOM   5039 C CA  . VAL C 3  342 ? -2.486  -6.522  -6.310  1.00 29.99 ? 334  VAL I CA  1 
ATOM   5040 C C   . VAL C 3  342 ? -2.245  -7.202  -7.648  1.00 30.32 ? 334  VAL I C   1 
ATOM   5041 O O   . VAL C 3  342 ? -1.117  -7.242  -8.145  1.00 29.61 ? 334  VAL I O   1 
ATOM   5042 C CB  . VAL C 3  342 ? -2.679  -5.000  -6.542  1.00 30.93 ? 334  VAL I CB  1 
ATOM   5043 C CG1 . VAL C 3  342 ? -3.558  -4.758  -7.768  1.00 30.58 ? 334  VAL I CG1 1 
ATOM   5044 C CG2 . VAL C 3  342 ? -3.334  -4.370  -5.322  1.00 29.67 ? 334  VAL I CG2 1 
ATOM   5045 N N   . GLU C 3  343 ? -3.305  -7.756  -8.218  1.00 31.51 ? 335  GLU I N   1 
ATOM   5046 C CA  . GLU C 3  343 ? -3.197  -8.419  -9.505  1.00 33.87 ? 335  GLU I CA  1 
ATOM   5047 C C   . GLU C 3  343 ? -4.043  -7.674  -10.528 1.00 33.69 ? 335  GLU I C   1 
ATOM   5048 O O   . GLU C 3  343 ? -5.193  -7.330  -10.261 1.00 33.72 ? 335  GLU I O   1 
ATOM   5049 C CB  . GLU C 3  343 ? -3.656  -9.875  -9.393  1.00 35.87 ? 335  GLU I CB  1 
ATOM   5050 C CG  . GLU C 3  343 ? -2.818  -10.704 -8.431  1.00 39.66 ? 335  GLU I CG  1 
ATOM   5051 C CD  . GLU C 3  343 ? -3.162  -12.181 -8.471  1.00 42.53 ? 335  GLU I CD  1 
ATOM   5052 O OE1 . GLU C 3  343 ? -4.331  -12.531 -8.208  1.00 44.85 ? 335  GLU I OE1 1 
ATOM   5053 O OE2 . GLU C 3  343 ? -2.260  -12.992 -8.767  1.00 45.60 ? 335  GLU I OE2 1 
ATOM   5054 N N   . VAL C 3  344 ? -3.451  -7.403  -11.686 1.00 33.87 ? 336  VAL I N   1 
ATOM   5055 C CA  . VAL C 3  344 ? -4.142  -6.710  -12.769 1.00 34.83 ? 336  VAL I CA  1 
ATOM   5056 C C   . VAL C 3  344 ? -4.312  -7.690  -13.925 1.00 35.64 ? 336  VAL I C   1 
ATOM   5057 O O   . VAL C 3  344 ? -3.330  -8.173  -14.485 1.00 34.93 ? 336  VAL I O   1 
ATOM   5058 C CB  . VAL C 3  344 ? -3.335  -5.491  -13.269 1.00 34.68 ? 336  VAL I CB  1 
ATOM   5059 C CG1 . VAL C 3  344 ? -4.020  -4.877  -14.485 1.00 33.93 ? 336  VAL I CG1 1 
ATOM   5060 C CG2 . VAL C 3  344 ? -3.215  -4.457  -12.166 1.00 34.26 ? 336  VAL I CG2 1 
ATOM   5061 N N   A ASP C 3  345 ? -5.563  -7.982  -14.268 0.20 36.82 ? 337  ASP I N   1 
ATOM   5062 N N   B ASP C 3  345 ? -5.560  -7.979  -14.277 0.80 36.83 ? 337  ASP I N   1 
ATOM   5063 C CA  A ASP C 3  345 ? -5.864  -8.909  -15.353 0.15 38.18 ? 337  ASP I CA  1 
ATOM   5064 C CA  B ASP C 3  345 ? -5.852  -8.899  -15.371 0.51 38.10 ? 337  ASP I CA  1 
ATOM   5065 C C   A ASP C 3  345 ? -6.896  -8.287  -16.293 0.10 39.07 ? 337  ASP I C   1 
ATOM   5066 C C   B ASP C 3  345 ? -6.879  -8.278  -16.312 0.25 38.86 ? 337  ASP I C   1 
ATOM   5067 O O   A ASP C 3  345 ? -7.215  -7.104  -16.176 0.41 38.60 ? 337  ASP I O   1 
ATOM   5068 O O   B ASP C 3  345 ? -7.183  -7.091  -16.209 0.59 37.79 ? 337  ASP I O   1 
ATOM   5069 C CB  A ASP C 3  345 ? -6.399  -10.224 -14.778 0.60 38.48 ? 337  ASP I CB  1 
ATOM   5070 C CB  B ASP C 3  345 ? -6.389  -10.220 -14.821 0.40 38.47 ? 337  ASP I CB  1 
ATOM   5071 C CG  A ASP C 3  345 ? -6.354  -11.360 -15.778 0.49 38.84 ? 337  ASP I CG  1 
ATOM   5072 C CG  B ASP C 3  345 ? -7.719  -10.057 -14.118 0.51 38.55 ? 337  ASP I CG  1 
ATOM   5073 O OD1 A ASP C 3  345 ? -5.242  -11.710 -16.229 0.14 38.87 ? 337  ASP I OD1 1 
ATOM   5074 O OD1 B ASP C 3  345 ? -7.799  -9.245  -13.172 0.10 38.86 ? 337  ASP I OD1 1 
ATOM   5075 O OD2 A ASP C 3  345 ? -7.427  -11.904 -16.114 0.10 38.79 ? 337  ASP I OD2 1 
ATOM   5076 O OD2 B ASP C 3  345 ? -8.684  -10.744 -14.507 0.44 38.84 ? 337  ASP I OD2 1 
ATOM   5077 N N   . GLU C 3  346 ? -7.418  -9.085  -17.221 1.00 40.07 ? 338  GLU I N   1 
ATOM   5078 C CA  . GLU C 3  346 ? -8.406  -8.596  -18.180 1.00 42.76 ? 338  GLU I CA  1 
ATOM   5079 C C   . GLU C 3  346 ? -9.853  -8.648  -17.686 1.00 44.46 ? 338  GLU I C   1 
ATOM   5080 O O   . GLU C 3  346 ? -10.690 -7.855  -18.121 1.00 44.90 ? 338  GLU I O   1 
ATOM   5081 C CB  . GLU C 3  346 ? -8.301  -9.377  -19.495 1.00 43.76 ? 338  GLU I CB  1 
ATOM   5082 C CG  . GLU C 3  346 ? -6.922  -9.346  -20.141 1.00 45.09 ? 338  GLU I CG  1 
ATOM   5083 C CD  . GLU C 3  346 ? -6.101  -10.588 -19.844 1.00 46.19 ? 338  GLU I CD  1 
ATOM   5084 O OE1 . GLU C 3  346 ? -5.955  -10.942 -18.655 1.00 46.61 ? 338  GLU I OE1 1 
ATOM   5085 O OE2 . GLU C 3  346 ? -5.598  -11.209 -20.805 1.00 46.93 ? 338  GLU I OE2 1 
ATOM   5086 N N   . SER C 3  347 ? -10.145 -9.575  -16.780 1.00 45.76 ? 339  SER I N   1 
ATOM   5087 C CA  . SER C 3  347 ? -11.497 -9.739  -16.249 1.00 47.52 ? 339  SER I CA  1 
ATOM   5088 C C   . SER C 3  347 ? -12.224 -8.434  -15.930 1.00 48.27 ? 339  SER I C   1 
ATOM   5089 O O   . SER C 3  347 ? -11.699 -7.561  -15.237 1.00 47.64 ? 339  SER I O   1 
ATOM   5090 C CB  . SER C 3  347 ? -11.470 -10.620 -14.996 1.00 48.20 ? 339  SER I CB  1 
ATOM   5091 O OG  . SER C 3  347 ? -10.969 -11.911 -15.296 1.00 50.07 ? 339  SER I OG  1 
ATOM   5092 N N   . GLY C 3  348 ? -13.445 -8.321  -16.443 1.00 49.44 ? 340  GLY I N   1 
ATOM   5093 C CA  . GLY C 3  348 ? -14.256 -7.141  -16.213 1.00 50.74 ? 340  GLY I CA  1 
ATOM   5094 C C   . GLY C 3  348 ? -15.716 -7.530  -16.087 1.00 52.14 ? 340  GLY I C   1 
ATOM   5095 O O   . GLY C 3  348 ? -16.079 -8.678  -16.335 1.00 52.12 ? 340  GLY I O   1 
ATOM   5096 N N   . THR C 3  349 ? -16.558 -6.576  -15.707 1.00 54.22 ? 341  THR I N   1 
ATOM   5097 C CA  . THR C 3  349 ? -17.982 -6.836  -15.541 1.00 56.48 ? 341  THR I CA  1 
ATOM   5098 C C   . THR C 3  349 ? -18.665 -7.218  -16.851 1.00 57.96 ? 341  THR I C   1 
ATOM   5099 O O   . THR C 3  349 ? -19.173 -8.331  -16.990 1.00 58.56 ? 341  THR I O   1 
ATOM   5100 C CB  . THR C 3  349 ? -18.709 -5.608  -14.949 1.00 56.95 ? 341  THR I CB  1 
ATOM   5101 O OG1 . THR C 3  349 ? -18.151 -5.293  -13.666 1.00 57.59 ? 341  THR I OG1 1 
ATOM   5102 C CG2 . THR C 3  349 ? -20.195 -5.893  -14.789 1.00 57.01 ? 341  THR I CG2 1 
ATOM   5103 N N   . ARG C 3  350 ? -18.674 -6.296  -17.808 1.00 59.45 ? 342  ARG I N   1 
ATOM   5104 C CA  . ARG C 3  350 ? -19.314 -6.541  -19.097 1.00 60.71 ? 342  ARG I CA  1 
ATOM   5105 C C   . ARG C 3  350 ? -18.323 -6.887  -20.202 1.00 61.96 ? 342  ARG I C   1 
ATOM   5106 O O   . ARG C 3  350 ? -17.115 -6.704  -20.049 1.00 62.13 ? 342  ARG I O   1 
ATOM   5107 C CB  . ARG C 3  350 ? -20.133 -5.316  -19.512 1.00 60.69 ? 342  ARG I CB  1 
ATOM   5108 N N   . ALA C 3  351 ? -18.851 -7.385  -21.317 1.00 63.31 ? 343  ALA I N   1 
ATOM   5109 C CA  . ALA C 3  351 ? -18.034 -7.764  -22.465 1.00 64.34 ? 343  ALA I CA  1 
ATOM   5110 C C   . ALA C 3  351 ? -17.305 -6.553  -23.036 1.00 64.89 ? 343  ALA I C   1 
ATOM   5111 O O   . ALA C 3  351 ? -16.430 -6.691  -23.893 1.00 65.58 ? 343  ALA I O   1 
ATOM   5112 C CB  . ALA C 3  351 ? -18.906 -8.406  -23.538 1.00 64.52 ? 343  ALA I CB  1 
ATOM   5113 N N   . ALA C 3  352 ? -17.683 -5.368  -22.567 1.00 65.02 ? 344  ALA I N   1 
ATOM   5114 C CA  . ALA C 3  352 ? -17.052 -4.129  -23.004 1.00 65.28 ? 344  ALA I CA  1 
ATOM   5115 C C   . ALA C 3  352 ? -17.141 -3.894  -24.506 1.00 65.47 ? 344  ALA I C   1 
ATOM   5116 O O   . ALA C 3  352 ? -16.213 -4.231  -25.243 1.00 65.88 ? 344  ALA I O   1 
ATOM   5117 C CB  . ALA C 3  352 ? -15.597 -4.129  -22.577 1.00 65.63 ? 344  ALA I CB  1 
ATOM   5118 N N   . ALA C 3  353 ? -18.247 -3.305  -24.957 1.00 65.37 ? 345  ALA I N   1 
ATOM   5119 C CA  . ALA C 3  353 ? -18.435 -3.023  -26.379 1.00 64.69 ? 345  ALA I CA  1 
ATOM   5120 C C   . ALA C 3  353 ? -19.824 -2.485  -26.711 1.00 64.02 ? 345  ALA I C   1 
ATOM   5121 O O   . ALA C 3  353 ? -20.693 -2.384  -25.843 1.00 64.33 ? 345  ALA I O   1 
ATOM   5122 C CB  . ALA C 3  353 ? -18.163 -4.281  -27.205 1.00 64.94 ? 345  ALA I CB  1 
ATOM   5123 N N   . ALA C 3  354 ? -20.010 -2.145  -27.983 0.00 62.61 ? 346  ALA I N   1 
ATOM   5124 C CA  . ALA C 3  354 ? -21.272 -1.627  -28.501 0.00 61.14 ? 346  ALA I CA  1 
ATOM   5125 C C   . ALA C 3  354 ? -22.015 -0.716  -27.531 0.00 60.02 ? 346  ALA I C   1 
ATOM   5126 O O   . ALA C 3  354 ? -21.408 -0.048  -26.693 0.00 59.96 ? 346  ALA I O   1 
ATOM   5127 C CB  . ALA C 3  354 ? -22.171 -2.787  -28.915 0.00 61.23 ? 346  ALA I CB  1 
ATOM   5128 N N   . THR C 3  355 ? -23.338 -0.694  -27.667 1.00 58.71 ? 347  THR I N   1 
ATOM   5129 C CA  . THR C 3  355 ? -24.202 0.119   -26.821 1.00 56.97 ? 347  THR I CA  1 
ATOM   5130 C C   . THR C 3  355 ? -24.029 1.608   -27.098 1.00 55.44 ? 347  THR I C   1 
ATOM   5131 O O   . THR C 3  355 ? -23.494 2.002   -28.136 1.00 56.35 ? 347  THR I O   1 
ATOM   5132 C CB  . THR C 3  355 ? -23.918 -0.176  -25.354 1.00 57.37 ? 347  THR I CB  1 
ATOM   5133 N N   . GLY C 3  356 ? -24.496 2.430   -26.164 1.00 53.32 ? 348  GLY I N   1 
ATOM   5134 C CA  . GLY C 3  356 ? -24.383 3.867   -26.318 1.00 49.50 ? 348  GLY I CA  1 
ATOM   5135 C C   . GLY C 3  356 ? -25.673 4.520   -26.771 1.00 47.35 ? 348  GLY I C   1 
ATOM   5136 O O   . GLY C 3  356 ? -26.374 5.145   -25.975 1.00 47.25 ? 348  GLY I O   1 
ATOM   5137 N N   . THR C 3  357 ? -25.991 4.372   -28.054 1.00 44.17 ? 349  THR I N   1 
ATOM   5138 C CA  . THR C 3  357 ? -27.199 4.967   -28.614 1.00 41.22 ? 349  THR I CA  1 
ATOM   5139 C C   . THR C 3  357 ? -27.787 4.113   -29.728 1.00 38.66 ? 349  THR I C   1 
ATOM   5140 O O   . THR C 3  357 ? -27.094 3.289   -30.324 1.00 38.58 ? 349  THR I O   1 
ATOM   5141 C CB  . THR C 3  357 ? -26.903 6.362   -29.190 1.00 40.92 ? 349  THR I CB  1 
ATOM   5142 O OG1 . THR C 3  357 ? -25.868 6.254   -30.174 1.00 40.32 ? 349  THR I OG1 1 
ATOM   5143 C CG2 . THR C 3  357 ? -26.449 7.314   -28.093 1.00 41.96 ? 349  THR I CG2 1 
ATOM   5144 N N   . ILE C 3  358 ? -29.071 4.314   -30.005 1.00 35.74 ? 350  ILE I N   1 
ATOM   5145 C CA  . ILE C 3  358 ? -29.747 3.570   -31.061 1.00 34.76 ? 350  ILE I CA  1 
ATOM   5146 C C   . ILE C 3  358 ? -29.313 4.148   -32.401 1.00 33.51 ? 350  ILE I C   1 
ATOM   5147 O O   . ILE C 3  358 ? -29.032 3.415   -33.350 1.00 33.17 ? 350  ILE I O   1 
ATOM   5148 C CB  . ILE C 3  358 ? -31.283 3.684   -30.937 1.00 35.11 ? 350  ILE I CB  1 
ATOM   5149 C CG1 . ILE C 3  358 ? -31.754 2.997   -29.650 1.00 37.02 ? 350  ILE I CG1 1 
ATOM   5150 C CG2 . ILE C 3  358 ? -31.952 3.061   -32.154 1.00 35.04 ? 350  ILE I CG2 1 
ATOM   5151 C CD1 . ILE C 3  358 ? -33.245 3.114   -29.397 1.00 37.85 ? 350  ILE I CD1 1 
ATOM   5152 N N   . PHE C 3  359 ? -29.259 5.474   -32.466 1.00 31.21 ? 351  PHE I N   1 
ATOM   5153 C CA  . PHE C 3  359 ? -28.852 6.157   -33.681 1.00 27.81 ? 351  PHE I CA  1 
ATOM   5154 C C   . PHE C 3  359 ? -27.342 6.128   -33.791 1.00 27.33 ? 351  PHE I C   1 
ATOM   5155 O O   . PHE C 3  359 ? -26.638 5.828   -32.824 1.00 26.61 ? 351  PHE I O   1 
ATOM   5156 C CB  . PHE C 3  359 ? -29.329 7.614   -33.661 1.00 29.38 ? 351  PHE I CB  1 
ATOM   5157 C CG  . PHE C 3  359 ? -28.826 8.403   -32.484 1.00 28.31 ? 351  PHE I CG  1 
ATOM   5158 C CD1 . PHE C 3  359 ? -27.489 8.784   -32.400 1.00 29.40 ? 351  PHE I CD1 1 
ATOM   5159 C CD2 . PHE C 3  359 ? -29.685 8.742   -31.442 1.00 29.33 ? 351  PHE I CD2 1 
ATOM   5160 C CE1 . PHE C 3  359 ? -27.015 9.488   -31.295 1.00 29.51 ? 351  PHE I CE1 1 
ATOM   5161 C CE2 . PHE C 3  359 ? -29.221 9.447   -30.332 1.00 29.00 ? 351  PHE I CE2 1 
ATOM   5162 C CZ  . PHE C 3  359 ? -27.884 9.819   -30.258 1.00 29.22 ? 351  PHE I CZ  1 
ATOM   5163 N N   . THR C 3  360 ? -26.844 6.427   -34.980 1.00 24.89 ? 352  THR I N   1 
ATOM   5164 C CA  . THR C 3  360 ? -25.416 6.476   -35.179 1.00 23.42 ? 352  THR I CA  1 
ATOM   5165 C C   . THR C 3  360 ? -25.101 7.831   -35.776 1.00 20.17 ? 352  THR I C   1 
ATOM   5166 O O   . THR C 3  360 ? -25.829 8.339   -36.631 1.00 20.95 ? 352  THR I O   1 
ATOM   5167 C CB  . THR C 3  360 ? -24.906 5.347   -36.104 1.00 25.13 ? 352  THR I CB  1 
ATOM   5168 O OG1 . THR C 3  360 ? -25.653 5.335   -37.325 1.00 24.64 ? 352  THR I OG1 1 
ATOM   5169 C CG2 . THR C 3  360 ? -25.044 4.003   -35.410 1.00 24.52 ? 352  THR I CG2 1 
ATOM   5170 N N   . PHE C 3  361 ? -24.035 8.433   -35.277 1.00 18.46 ? 353  PHE I N   1 
ATOM   5171 C CA  . PHE C 3  361 ? -23.603 9.728   -35.766 1.00 16.76 ? 353  PHE I CA  1 
ATOM   5172 C C   . PHE C 3  361 ? -23.110 9.555   -37.190 1.00 17.37 ? 353  PHE I C   1 
ATOM   5173 O O   . PHE C 3  361 ? -22.700 8.460   -37.586 1.00 17.51 ? 353  PHE I O   1 
ATOM   5174 C CB  . PHE C 3  361 ? -22.443 10.248  -34.917 1.00 18.26 ? 353  PHE I CB  1 
ATOM   5175 C CG  . PHE C 3  361 ? -22.810 10.544  -33.493 1.00 20.28 ? 353  PHE I CG  1 
ATOM   5176 C CD1 . PHE C 3  361 ? -21.925 10.238  -32.461 1.00 21.18 ? 353  PHE I CD1 1 
ATOM   5177 C CD2 . PHE C 3  361 ? -24.009 11.172  -33.184 1.00 20.34 ? 353  PHE I CD2 1 
ATOM   5178 C CE1 . PHE C 3  361 ? -22.231 10.555  -31.143 1.00 22.66 ? 353  PHE I CE1 1 
ATOM   5179 C CE2 . PHE C 3  361 ? -24.324 11.495  -31.867 1.00 21.84 ? 353  PHE I CE2 1 
ATOM   5180 C CZ  . PHE C 3  361 ? -23.435 11.186  -30.847 1.00 23.42 ? 353  PHE I CZ  1 
ATOM   5181 N N   . ARG C 3  362 ? -23.159 10.631  -37.966 1.00 13.64 ? 354  ARG I N   1 
ATOM   5182 C CA  . ARG C 3  362 ? -22.646 10.593  -39.320 1.00 12.86 ? 354  ARG I CA  1 
ATOM   5183 C C   . ARG C 3  362 ? -21.450 11.519  -39.436 1.00 13.96 ? 354  ARG I C   1 
ATOM   5184 O O   . ARG C 3  362 ? -20.971 11.815  -40.523 1.00 12.89 ? 354  ARG I O   1 
ATOM   5185 C CB  . ARG C 3  362 ? -23.739 10.907  -40.337 1.00 13.25 ? 354  ARG I CB  1 
ATOM   5186 C CG  . ARG C 3  362 ? -24.585 9.658   -40.530 1.00 13.72 ? 354  ARG I CG  1 
ATOM   5187 C CD  . ARG C 3  362 ? -25.673 9.751   -41.559 1.00 12.91 ? 354  ARG I CD  1 
ATOM   5188 N NE  . ARG C 3  362 ? -26.213 8.400   -41.731 1.00 14.65 ? 354  ARG I NE  1 
ATOM   5189 C CZ  . ARG C 3  362 ? -27.099 8.044   -42.649 1.00 16.48 ? 354  ARG I CZ  1 
ATOM   5190 N NH1 . ARG C 3  362 ? -27.582 8.939   -43.504 1.00 14.19 ? 354  ARG I NH1 1 
ATOM   5191 N NH2 . ARG C 3  362 ? -27.466 6.769   -42.736 1.00 14.88 ? 354  ARG I NH2 1 
ATOM   5192 N N   . SER C 3  363 ? -20.970 11.950  -38.275 1.00 14.64 ? 355  SER I N   1 
ATOM   5193 C CA  . SER C 3  363 ? -19.769 12.767  -38.192 1.00 17.99 ? 355  SER I CA  1 
ATOM   5194 C C   . SER C 3  363 ? -18.632 11.745  -38.293 1.00 20.29 ? 355  SER I C   1 
ATOM   5195 O O   . SER C 3  363 ? -18.865 10.542  -38.126 1.00 20.32 ? 355  SER I O   1 
ATOM   5196 C CB  . SER C 3  363 ? -19.716 13.483  -36.840 1.00 18.01 ? 355  SER I CB  1 
ATOM   5197 O OG  . SER C 3  363 ? -19.998 12.586  -35.779 1.00 17.00 ? 355  SER I OG  1 
ATOM   5198 N N   . ALA C 3  364 ? -17.416 12.198  -38.580 1.00 20.94 ? 356  ALA I N   1 
ATOM   5199 C CA  . ALA C 3  364 ? -16.289 11.273  -38.668 1.00 23.86 ? 356  ALA I CA  1 
ATOM   5200 C C   . ALA C 3  364 ? -16.039 10.674  -37.281 1.00 25.40 ? 356  ALA I C   1 
ATOM   5201 O O   . ALA C 3  364 ? -16.319 11.308  -36.266 1.00 24.66 ? 356  ALA I O   1 
ATOM   5202 C CB  . ALA C 3  364 ? -15.045 12.003  -39.168 1.00 23.71 ? 356  ALA I CB  1 
ATOM   5203 N N   . ARG C 3  365 ? -15.526 9.448   -37.234 1.00 29.61 ? 357  ARG I N   1 
ATOM   5204 C CA  . ARG C 3  365 ? -15.265 8.795   -35.953 1.00 32.85 ? 357  ARG I CA  1 
ATOM   5205 C C   . ARG C 3  365 ? -14.185 9.515   -35.152 1.00 34.70 ? 357  ARG I C   1 
ATOM   5206 O O   . ARG C 3  365 ? -13.253 10.089  -35.720 1.00 34.63 ? 357  ARG I O   1 
ATOM   5207 C CB  . ARG C 3  365 ? -14.857 7.336   -36.171 1.00 34.28 ? 357  ARG I CB  1 
ATOM   5208 C CG  . ARG C 3  365 ? -13.526 7.150   -36.884 1.00 36.64 ? 357  ARG I CG  1 
ATOM   5209 C CD  . ARG C 3  365 ? -13.278 5.677   -37.187 1.00 39.00 ? 357  ARG I CD  1 
ATOM   5210 N NE  . ARG C 3  365 ? -14.328 5.129   -38.043 1.00 40.69 ? 357  ARG I NE  1 
ATOM   5211 C CZ  . ARG C 3  365 ? -14.394 3.862   -38.441 1.00 42.10 ? 357  ARG I CZ  1 
ATOM   5212 N NH1 . ARG C 3  365 ? -15.391 3.466   -39.221 1.00 41.70 ? 357  ARG I NH1 1 
ATOM   5213 N NH2 . ARG C 3  365 ? -13.467 2.991   -38.059 1.00 41.80 ? 357  ARG I NH2 1 
ATOM   5214 N N   . LEU C 3  366 ? -14.317 9.478   -33.829 1.00 35.58 ? 358  LEU I N   1 
ATOM   5215 C CA  . LEU C 3  366 ? -13.357 10.126  -32.945 1.00 37.94 ? 358  LEU I CA  1 
ATOM   5216 C C   . LEU C 3  366 ? -11.924 9.732   -33.282 1.00 38.65 ? 358  LEU I C   1 
ATOM   5217 O O   . LEU C 3  366 ? -11.642 8.570   -33.580 1.00 37.96 ? 358  LEU I O   1 
ATOM   5218 C CB  . LEU C 3  366 ? -13.642 9.759   -31.484 1.00 38.13 ? 358  LEU I CB  1 
ATOM   5219 C CG  . LEU C 3  366 ? -15.009 10.103  -30.886 1.00 38.83 ? 358  LEU I CG  1 
ATOM   5220 C CD1 . LEU C 3  366 ? -15.021 9.713   -29.415 1.00 38.54 ? 358  LEU I CD1 1 
ATOM   5221 C CD2 . LEU C 3  366 ? -15.291 11.589  -31.039 1.00 39.63 ? 358  LEU I CD2 1 
ATOM   5222 N N   . ASN C 3  367 ? -11.024 10.710  -33.243 1.00 39.30 ? 359  ASN I N   1 
ATOM   5223 C CA  . ASN C 3  367 ? -9.612  10.466  -33.512 1.00 40.90 ? 359  ASN I CA  1 
ATOM   5224 C C   . ASN C 3  367 ? -9.060  9.688   -32.321 1.00 40.29 ? 359  ASN I C   1 
ATOM   5225 O O   . ASN C 3  367 ? -9.295  10.063  -31.173 1.00 40.24 ? 359  ASN I O   1 
ATOM   5226 C CB  . ASN C 3  367 ? -8.864  11.794  -33.654 1.00 43.54 ? 359  ASN I CB  1 
ATOM   5227 C CG  . ASN C 3  367 ? -7.358  11.621  -33.633 1.00 45.91 ? 359  ASN I CG  1 
ATOM   5228 O OD1 . ASN C 3  367 ? -6.671  12.141  -32.753 1.00 48.52 ? 359  ASN I OD1 1 
ATOM   5229 N ND2 . ASN C 3  367 ? -6.835  10.889  -34.610 1.00 47.24 ? 359  ASN I ND2 1 
ATOM   5230 N N   . SER C 3  368 ? -8.339  8.605   -32.589 1.00 40.65 ? 360  SER I N   1 
ATOM   5231 C CA  . SER C 3  368 ? -7.780  7.793   -31.512 1.00 41.39 ? 360  SER I CA  1 
ATOM   5232 C C   . SER C 3  368 ? -6.319  8.096   -31.219 1.00 41.28 ? 360  SER I C   1 
ATOM   5233 O O   . SER C 3  368 ? -5.476  8.120   -32.118 1.00 40.60 ? 360  SER I O   1 
ATOM   5234 C CB  . SER C 3  368 ? -7.940  6.307   -31.828 1.00 42.34 ? 360  SER I CB  1 
ATOM   5235 O OG  . SER C 3  368 ? -9.304  5.932   -31.771 1.00 46.06 ? 360  SER I OG  1 
ATOM   5236 N N   . GLN C 3  369 ? -6.034  8.327   -29.942 1.00 40.35 ? 361  GLN I N   1 
ATOM   5237 C CA  . GLN C 3  369 ? -4.688  8.630   -29.482 1.00 39.91 ? 361  GLN I CA  1 
ATOM   5238 C C   . GLN C 3  369 ? -4.080  7.349   -28.918 1.00 38.72 ? 361  GLN I C   1 
ATOM   5239 O O   . GLN C 3  369 ? -4.777  6.526   -28.328 1.00 37.57 ? 361  GLN I O   1 
ATOM   5240 C CB  . GLN C 3  369 ? -4.748  9.706   -28.398 1.00 41.43 ? 361  GLN I CB  1 
ATOM   5241 C CG  . GLN C 3  369 ? -3.414  10.319  -28.026 1.00 43.81 ? 361  GLN I CG  1 
ATOM   5242 C CD  . GLN C 3  369 ? -3.565  11.395  -26.965 1.00 45.66 ? 361  GLN I CD  1 
ATOM   5243 O OE1 . GLN C 3  369 ? -4.333  12.345  -27.134 1.00 47.20 ? 361  GLN I OE1 1 
ATOM   5244 N NE2 . GLN C 3  369 ? -2.836  11.251  -25.865 1.00 45.03 ? 361  GLN I NE2 1 
ATOM   5245 N N   . ARG C 3  370 ? -2.777  7.188   -29.103 1.00 37.86 ? 362  ARG I N   1 
ATOM   5246 C CA  . ARG C 3  370 ? -2.082  6.002   -28.629 1.00 37.33 ? 362  ARG I CA  1 
ATOM   5247 C C   . ARG C 3  370 ? -1.445  6.251   -27.264 1.00 34.67 ? 362  ARG I C   1 
ATOM   5248 O O   . ARG C 3  370 ? -0.682  7.198   -27.093 1.00 35.52 ? 362  ARG I O   1 
ATOM   5249 C CB  . ARG C 3  370 ? -1.012  5.614   -29.651 1.00 39.69 ? 362  ARG I CB  1 
ATOM   5250 C CG  . ARG C 3  370 ? -0.608  4.158   -29.652 1.00 42.75 ? 362  ARG I CG  1 
ATOM   5251 C CD  . ARG C 3  370 ? 0.149   3.847   -30.932 1.00 45.05 ? 362  ARG I CD  1 
ATOM   5252 N NE  . ARG C 3  370 ? 1.294   4.737   -31.106 1.00 47.47 ? 362  ARG I NE  1 
ATOM   5253 C CZ  . ARG C 3  370 ? 1.997   4.843   -32.229 1.00 48.93 ? 362  ARG I CZ  1 
ATOM   5254 N NH1 . ARG C 3  370 ? 3.025   5.679   -32.292 1.00 49.04 ? 362  ARG I NH1 1 
ATOM   5255 N NH2 . ARG C 3  370 ? 1.669   4.121   -33.291 1.00 49.50 ? 362  ARG I NH2 1 
ATOM   5256 N N   . LEU C 3  371 ? -1.780  5.407   -26.292 1.00 33.07 ? 363  LEU I N   1 
ATOM   5257 C CA  . LEU C 3  371 ? -1.225  5.517   -24.944 1.00 30.49 ? 363  LEU I CA  1 
ATOM   5258 C C   . LEU C 3  371 ? -0.664  4.145   -24.592 1.00 29.72 ? 363  LEU I C   1 
ATOM   5259 O O   . LEU C 3  371 ? -1.413  3.209   -24.310 1.00 28.17 ? 363  LEU I O   1 
ATOM   5260 C CB  . LEU C 3  371 ? -2.307  5.919   -23.936 1.00 30.60 ? 363  LEU I CB  1 
ATOM   5261 C CG  . LEU C 3  371 ? -1.835  6.090   -22.487 1.00 31.51 ? 363  LEU I CG  1 
ATOM   5262 C CD1 . LEU C 3  371 ? -0.702  7.104   -22.431 1.00 31.84 ? 363  LEU I CD1 1 
ATOM   5263 C CD2 . LEU C 3  371 ? -2.998  6.538   -21.614 1.00 31.06 ? 363  LEU I CD2 1 
ATOM   5264 N N   . VAL C 3  372 ? 0.658   4.030   -24.621 1.00 28.46 ? 364  VAL I N   1 
ATOM   5265 C CA  . VAL C 3  372 ? 1.309   2.758   -24.344 1.00 28.54 ? 364  VAL I CA  1 
ATOM   5266 C C   . VAL C 3  372 ? 2.142   2.781   -23.072 1.00 27.67 ? 364  VAL I C   1 
ATOM   5267 O O   . VAL C 3  372 ? 3.117   3.526   -22.972 1.00 28.36 ? 364  VAL I O   1 
ATOM   5268 C CB  . VAL C 3  372 ? 2.229   2.355   -25.514 1.00 28.87 ? 364  VAL I CB  1 
ATOM   5269 C CG1 . VAL C 3  372 ? 2.697   0.922   -25.336 1.00 29.72 ? 364  VAL I CG1 1 
ATOM   5270 C CG2 . VAL C 3  372 ? 1.496   2.530   -26.839 1.00 28.32 ? 364  VAL I CG2 1 
ATOM   5271 N N   . PHE C 3  373 ? 1.755   1.967   -22.096 1.00 27.93 ? 365  PHE I N   1 
ATOM   5272 C CA  . PHE C 3  373 ? 2.508   1.900   -20.851 1.00 28.61 ? 365  PHE I CA  1 
ATOM   5273 C C   . PHE C 3  373 ? 3.595   0.849   -21.011 1.00 29.45 ? 365  PHE I C   1 
ATOM   5274 O O   . PHE C 3  373 ? 3.458   -0.282  -20.543 1.00 29.36 ? 365  PHE I O   1 
ATOM   5275 C CB  . PHE C 3  373 ? 1.593   1.555   -19.672 1.00 28.14 ? 365  PHE I CB  1 
ATOM   5276 C CG  . PHE C 3  373 ? 0.717   2.697   -19.236 1.00 27.45 ? 365  PHE I CG  1 
ATOM   5277 C CD1 . PHE C 3  373 ? -0.460  2.992   -19.917 1.00 27.33 ? 365  PHE I CD1 1 
ATOM   5278 C CD2 . PHE C 3  373 ? 1.098   3.511   -18.175 1.00 26.97 ? 365  PHE I CD2 1 
ATOM   5279 C CE1 . PHE C 3  373 ? -1.245  4.086   -19.548 1.00 26.56 ? 365  PHE I CE1 1 
ATOM   5280 C CE2 . PHE C 3  373 ? 0.322   4.607   -17.797 1.00 26.61 ? 365  PHE I CE2 1 
ATOM   5281 C CZ  . PHE C 3  373 ? -0.852  4.895   -18.487 1.00 26.24 ? 365  PHE I CZ  1 
ATOM   5282 N N   . ASN C 3  374 ? 4.669   1.236   -21.696 1.00 29.45 ? 366  ASN I N   1 
ATOM   5283 C CA  . ASN C 3  374 ? 5.791   0.337   -21.941 1.00 29.67 ? 366  ASN I CA  1 
ATOM   5284 C C   . ASN C 3  374 ? 7.080   0.808   -21.280 1.00 29.93 ? 366  ASN I C   1 
ATOM   5285 O O   . ASN C 3  374 ? 8.179   0.463   -21.716 1.00 29.02 ? 366  ASN I O   1 
ATOM   5286 C CB  . ASN C 3  374 ? 6.019   0.152   -23.444 1.00 30.66 ? 366  ASN I CB  1 
ATOM   5287 C CG  . ASN C 3  374 ? 6.142   1.464   -24.186 1.00 30.92 ? 366  ASN I CG  1 
ATOM   5288 O OD1 . ASN C 3  374 ? 6.515   2.491   -23.613 1.00 30.82 ? 366  ASN I OD1 1 
ATOM   5289 N ND2 . ASN C 3  374 ? 5.847   1.433   -25.481 1.00 34.02 ? 366  ASN I ND2 1 
ATOM   5290 N N   . ARG C 3  375 ? 6.937   1.627   -20.244 1.00 29.35 ? 367  ARG I N   1 
ATOM   5291 C CA  . ARG C 3  375 ? 8.077   2.100   -19.472 1.00 30.02 ? 367  ARG I CA  1 
ATOM   5292 C C   . ARG C 3  375 ? 7.550   2.366   -18.067 1.00 28.92 ? 367  ARG I C   1 
ATOM   5293 O O   . ARG C 3  375 ? 6.337   2.385   -17.857 1.00 27.74 ? 367  ARG I O   1 
ATOM   5294 C CB  . ARG C 3  375 ? 8.721   3.349   -20.095 1.00 31.52 ? 367  ARG I CB  1 
ATOM   5295 C CG  . ARG C 3  375 ? 7.909   4.625   -20.102 1.00 33.31 ? 367  ARG I CG  1 
ATOM   5296 C CD  . ARG C 3  375 ? 8.819   5.779   -20.528 1.00 35.21 ? 367  ARG I CD  1 
ATOM   5297 N NE  . ARG C 3  375 ? 8.098   7.032   -20.727 1.00 33.72 ? 367  ARG I NE  1 
ATOM   5298 C CZ  . ARG C 3  375 ? 7.259   7.261   -21.731 1.00 32.20 ? 367  ARG I CZ  1 
ATOM   5299 N NH1 . ARG C 3  375 ? 7.034   6.321   -22.640 1.00 33.86 ? 367  ARG I NH1 1 
ATOM   5300 N NH2 . ARG C 3  375 ? 6.640   8.429   -21.821 1.00 30.93 ? 367  ARG I NH2 1 
ATOM   5301 N N   . PRO C 3  376 ? 8.445   2.553   -17.084 1.00 29.43 ? 368  PRO I N   1 
ATOM   5302 C CA  . PRO C 3  376 ? 8.011   2.803   -15.704 1.00 28.43 ? 368  PRO I CA  1 
ATOM   5303 C C   . PRO C 3  376 ? 6.845   3.776   -15.548 1.00 27.86 ? 368  PRO I C   1 
ATOM   5304 O O   . PRO C 3  376 ? 6.904   4.917   -16.012 1.00 27.24 ? 368  PRO I O   1 
ATOM   5305 C CB  . PRO C 3  376 ? 9.286   3.303   -15.032 1.00 29.09 ? 368  PRO I CB  1 
ATOM   5306 C CG  . PRO C 3  376 ? 10.346  2.505   -15.736 1.00 29.94 ? 368  PRO I CG  1 
ATOM   5307 C CD  . PRO C 3  376 ? 9.914   2.627   -17.188 1.00 29.65 ? 368  PRO I CD  1 
ATOM   5308 N N   . PHE C 3  377 ? 5.782   3.311   -14.894 1.00 25.11 ? 369  PHE I N   1 
ATOM   5309 C CA  . PHE C 3  377 ? 4.613   4.146   -14.663 1.00 23.40 ? 369  PHE I CA  1 
ATOM   5310 C C   . PHE C 3  377 ? 4.159   4.068   -13.213 1.00 22.77 ? 369  PHE I C   1 
ATOM   5311 O O   . PHE C 3  377 ? 4.550   3.165   -12.475 1.00 23.69 ? 369  PHE I O   1 
ATOM   5312 C CB  . PHE C 3  377 ? 3.453   3.742   -15.587 1.00 23.87 ? 369  PHE I CB  1 
ATOM   5313 C CG  . PHE C 3  377 ? 3.020   2.303   -15.451 1.00 23.14 ? 369  PHE I CG  1 
ATOM   5314 C CD1 . PHE C 3  377 ? 3.683   1.290   -16.139 1.00 24.50 ? 369  PHE I CD1 1 
ATOM   5315 C CD2 . PHE C 3  377 ? 1.933   1.965   -14.652 1.00 23.40 ? 369  PHE I CD2 1 
ATOM   5316 C CE1 . PHE C 3  377 ? 3.267   -0.037  -16.036 1.00 22.76 ? 369  PHE I CE1 1 
ATOM   5317 C CE2 . PHE C 3  377 ? 1.509   0.641   -14.541 1.00 23.56 ? 369  PHE I CE2 1 
ATOM   5318 C CZ  . PHE C 3  377 ? 2.177   -0.361  -15.235 1.00 24.64 ? 369  PHE I CZ  1 
ATOM   5319 N N   . LEU C 3  378 ? 3.345   5.035   -12.809 1.00 21.58 ? 370  LEU I N   1 
ATOM   5320 C CA  . LEU C 3  378 ? 2.819   5.075   -11.454 1.00 20.47 ? 370  LEU I CA  1 
ATOM   5321 C C   . LEU C 3  378 ? 1.381   4.579   -11.487 1.00 21.52 ? 370  LEU I C   1 
ATOM   5322 O O   . LEU C 3  378 ? 0.712   4.644   -12.524 1.00 19.55 ? 370  LEU I O   1 
ATOM   5323 C CB  . LEU C 3  378 ? 2.874   6.505   -10.909 1.00 22.23 ? 370  LEU I CB  1 
ATOM   5324 C CG  . LEU C 3  378 ? 4.281   7.099   -10.815 1.00 23.27 ? 370  LEU I CG  1 
ATOM   5325 C CD1 . LEU C 3  378 ? 4.207   8.545   -10.347 1.00 25.64 ? 370  LEU I CD1 1 
ATOM   5326 C CD2 . LEU C 3  378 ? 5.121   6.262   -9.858  1.00 25.43 ? 370  LEU I CD2 1 
ATOM   5327 N N   A MET C 3  379 ? 0.895   4.092   -10.356 0.10 19.36 ? 371  MET I N   1 
ATOM   5328 N N   B MET C 3  379 ? 0.913   4.066   -10.351 0.77 20.95 ? 371  MET I N   1 
ATOM   5329 C CA  A MET C 3  379 ? -0.476  3.631   -10.304 0.10 18.45 ? 371  MET I CA  1 
ATOM   5330 C CA  B MET C 3  379 ? -0.435  3.519   -10.254 0.90 22.08 ? 371  MET I CA  1 
ATOM   5331 C C   A MET C 3  379 ? -1.095  3.918   -8.951  0.41 19.20 ? 371  MET I C   1 
ATOM   5332 C C   B MET C 3  379 ? -1.119  3.815   -8.919  0.37 21.86 ? 371  MET I C   1 
ATOM   5333 O O   A MET C 3  379 ? -0.429  3.872   -7.917  0.70 17.50 ? 371  MET I O   1 
ATOM   5334 O O   B MET C 3  379 ? -0.517  3.662   -7.856  0.11 21.41 ? 371  MET I O   1 
ATOM   5335 C CB  A MET C 3  379 ? -0.564  2.135   -10.621 0.22 16.12 ? 371  MET I CB  1 
ATOM   5336 C CB  B MET C 3  379 ? -0.365  2.004   -10.486 0.78 23.99 ? 371  MET I CB  1 
ATOM   5337 C CG  A MET C 3  379 ? 0.018   1.216   -9.568  0.29 13.32 ? 371  MET I CG  1 
ATOM   5338 C CG  B MET C 3  379 ? -1.585  1.207   -10.056 0.57 25.97 ? 371  MET I CG  1 
ATOM   5339 S SD  A MET C 3  379 ? -0.179  -0.508  -10.047 0.19 7.90  ? 371  MET I SD  1 
ATOM   5340 S SD  B MET C 3  379 ? -1.353  -0.574  -10.314 0.53 29.47 ? 371  MET I SD  1 
ATOM   5341 C CE  A MET C 3  379 ? -1.871  -0.818  -9.536  0.18 10.35 ? 371  MET I CE  1 
ATOM   5342 C CE  B MET C 3  379 ? 0.146   -0.860  -9.391  0.14 28.15 ? 371  MET I CE  1 
ATOM   5343 N N   . PHE C 3  380 ? -2.379  4.241   -8.984  1.00 20.79 ? 372  PHE I N   1 
ATOM   5344 C CA  . PHE C 3  380 ? -3.154  4.536   -7.785  1.00 22.32 ? 372  PHE I CA  1 
ATOM   5345 C C   . PHE C 3  380 ? -4.408  3.692   -7.905  1.00 23.48 ? 372  PHE I C   1 
ATOM   5346 O O   . PHE C 3  380 ? -4.861  3.395   -9.007  1.00 24.35 ? 372  PHE I O   1 
ATOM   5347 C CB  . PHE C 3  380 ? -3.648  5.990   -7.743  1.00 24.18 ? 372  PHE I CB  1 
ATOM   5348 C CG  . PHE C 3  380 ? -2.591  7.021   -7.464  1.00 26.63 ? 372  PHE I CG  1 
ATOM   5349 C CD1 . PHE C 3  380 ? -1.548  7.242   -8.356  1.00 27.78 ? 372  PHE I CD1 1 
ATOM   5350 C CD2 . PHE C 3  380 ? -2.702  7.845   -6.347  1.00 27.31 ? 372  PHE I CD2 1 
ATOM   5351 C CE1 . PHE C 3  380 ? -0.633  8.278   -8.142  1.00 27.63 ? 372  PHE I CE1 1 
ATOM   5352 C CE2 . PHE C 3  380 ? -1.793  8.882   -6.124  1.00 28.32 ? 372  PHE I CE2 1 
ATOM   5353 C CZ  . PHE C 3  380 ? -0.758  9.099   -7.025  1.00 26.37 ? 372  PHE I CZ  1 
ATOM   5354 N N   . ILE C 3  381 ? -4.959  3.287   -6.771  1.00 23.44 ? 373  ILE I N   1 
ATOM   5355 C CA  . ILE C 3  381 ? -6.227  2.576   -6.773  1.00 24.81 ? 373  ILE I CA  1 
ATOM   5356 C C   . ILE C 3  381 ? -6.959  3.342   -5.701  1.00 26.80 ? 373  ILE I C   1 
ATOM   5357 O O   . ILE C 3  381 ? -6.534  3.369   -4.544  1.00 25.59 ? 373  ILE I O   1 
ATOM   5358 C CB  . ILE C 3  381 ? -6.112  1.097   -6.395  1.00 24.96 ? 373  ILE I CB  1 
ATOM   5359 C CG1 . ILE C 3  381 ? -5.428  0.337   -7.532  1.00 24.03 ? 373  ILE I CG1 1 
ATOM   5360 C CG2 . ILE C 3  381 ? -7.511  0.514   -6.159  1.00 25.38 ? 373  ILE I CG2 1 
ATOM   5361 C CD1 . ILE C 3  381 ? -5.405  -1.167  -7.355  1.00 25.97 ? 373  ILE I CD1 1 
ATOM   5362 N N   . VAL C 3  382 ? -8.043  3.996   -6.098  1.00 28.08 ? 374  VAL I N   1 
ATOM   5363 C CA  . VAL C 3  382 ? -8.782  4.811   -5.160  1.00 31.70 ? 374  VAL I CA  1 
ATOM   5364 C C   . VAL C 3  382 ? -10.272 4.568   -5.122  1.00 34.04 ? 374  VAL I C   1 
ATOM   5365 O O   . VAL C 3  382 ? -10.902 4.244   -6.125  1.00 33.22 ? 374  VAL I O   1 
ATOM   5366 C CB  . VAL C 3  382 ? -8.588  6.305   -5.458  1.00 31.80 ? 374  VAL I CB  1 
ATOM   5367 C CG1 . VAL C 3  382 ? -7.114  6.632   -5.519  1.00 32.87 ? 374  VAL I CG1 1 
ATOM   5368 C CG2 . VAL C 3  382 ? -9.269  6.664   -6.770  1.00 32.76 ? 374  VAL I CG2 1 
ATOM   5369 N N   . ASP C 3  383 ? -10.821 4.720   -3.930  1.00 37.31 ? 375  ASP I N   1 
ATOM   5370 C CA  . ASP C 3  383 ? -12.248 4.600   -3.681  1.00 40.85 ? 375  ASP I CA  1 
ATOM   5371 C C   . ASP C 3  383 ? -12.462 5.973   -3.054  1.00 42.90 ? 375  ASP I C   1 
ATOM   5372 O O   . ASP C 3  383 ? -12.258 6.992   -3.699  1.00 44.18 ? 375  ASP I O   1 
ATOM   5373 C CB  . ASP C 3  383 ? -12.524 3.502   -2.658  1.00 42.86 ? 375  ASP I CB  1 
ATOM   5374 C CG  . ASP C 3  383 ? -13.741 2.673   -3.009  1.00 45.03 ? 375  ASP I CG  1 
ATOM   5375 O OD1 . ASP C 3  383 ? -14.713 3.263   -3.531  1.00 44.86 ? 375  ASP I OD1 1 
ATOM   5376 O OD2 . ASP C 3  383 ? -13.741 1.447   -2.757  1.00 46.80 ? 375  ASP I OD2 1 
ATOM   5377 N N   . ASN C 3  384 ? -12.857 6.023   -1.786  1.00 43.25 ? 376  ASN I N   1 
ATOM   5378 C CA  . ASN C 3  384 ? -12.985 7.302   -1.108  1.00 44.72 ? 376  ASN I CA  1 
ATOM   5379 C C   . ASN C 3  384 ? -11.589 7.578   -0.575  1.00 43.75 ? 376  ASN I C   1 
ATOM   5380 O O   . ASN C 3  384 ? -11.200 8.722   -0.356  1.00 45.45 ? 376  ASN I O   1 
ATOM   5381 C CB  . ASN C 3  384 ? -13.975 7.199   0.052   1.00 47.48 ? 376  ASN I CB  1 
ATOM   5382 C CG  . ASN C 3  384 ? -15.410 7.235   -0.419  1.00 49.92 ? 376  ASN I CG  1 
ATOM   5383 O OD1 . ASN C 3  384 ? -15.827 8.174   -1.100  1.00 50.94 ? 376  ASN I OD1 1 
ATOM   5384 N ND2 . ASN C 3  384 ? -16.179 6.214   -0.053  1.00 50.78 ? 376  ASN I ND2 1 
ATOM   5385 N N   . ASN C 3  385 ? -10.816 6.515   -0.397  1.00 41.54 ? 377  ASN I N   1 
ATOM   5386 C CA  . ASN C 3  385 ? -9.457  6.605   0.114   1.00 38.70 ? 377  ASN I CA  1 
ATOM   5387 C C   . ASN C 3  385 ? -8.485  6.035   -0.913  1.00 35.95 ? 377  ASN I C   1 
ATOM   5388 O O   . ASN C 3  385 ? -8.889  5.408   -1.898  1.00 36.15 ? 377  ASN I O   1 
ATOM   5389 C CB  . ASN C 3  385 ? -9.308  5.796   1.407   1.00 40.24 ? 377  ASN I CB  1 
ATOM   5390 C CG  . ASN C 3  385 ? -10.347 6.143   2.440   1.00 41.42 ? 377  ASN I CG  1 
ATOM   5391 O OD1 . ASN C 3  385 ? -11.506 5.753   2.322   1.00 43.36 ? 377  ASN I OD1 1 
ATOM   5392 N ND2 . ASN C 3  385 ? -9.937  6.878   3.467   1.00 41.98 ? 377  ASN I ND2 1 
ATOM   5393 N N   . ILE C 3  386 ? -7.198  6.259   -0.665  1.00 32.39 ? 378  ILE I N   1 
ATOM   5394 C CA  . ILE C 3  386 ? -6.139  5.751   -1.523  1.00 29.49 ? 378  ILE I CA  1 
ATOM   5395 C C   . ILE C 3  386 ? -5.837  4.341   -1.031  1.00 27.75 ? 378  ILE I C   1 
ATOM   5396 O O   . ILE C 3  386 ? -5.111  4.151   -0.051  1.00 27.60 ? 378  ILE I O   1 
ATOM   5397 C CB  . ILE C 3  386 ? -4.842  6.587   -1.404  1.00 29.93 ? 378  ILE I CB  1 
ATOM   5398 C CG1 . ILE C 3  386 ? -5.094  8.046   -1.789  1.00 30.09 ? 378  ILE I CG1 1 
ATOM   5399 C CG2 . ILE C 3  386 ? -3.779  6.003   -2.306  1.00 28.84 ? 378  ILE I CG2 1 
ATOM   5400 C CD1 . ILE C 3  386 ? -3.839  8.918   -1.740  1.00 30.41 ? 378  ILE I CD1 1 
ATOM   5401 N N   . LEU C 3  387 ? -6.406  3.357   -1.712  1.00 26.64 ? 379  LEU I N   1 
ATOM   5402 C CA  . LEU C 3  387 ? -6.218  1.965   -1.348  1.00 25.48 ? 379  LEU I CA  1 
ATOM   5403 C C   . LEU C 3  387 ? -4.813  1.471   -1.670  1.00 25.78 ? 379  LEU I C   1 
ATOM   5404 O O   . LEU C 3  387 ? -4.215  0.738   -0.887  1.00 24.65 ? 379  LEU I O   1 
ATOM   5405 C CB  . LEU C 3  387 ? -7.256  1.102   -2.067  1.00 27.39 ? 379  LEU I CB  1 
ATOM   5406 C CG  . LEU C 3  387 ? -8.714  1.511   -1.834  1.00 28.45 ? 379  LEU I CG  1 
ATOM   5407 C CD1 . LEU C 3  387 ? -9.626  0.585   -2.617  1.00 31.05 ? 379  LEU I CD1 1 
ATOM   5408 C CD2 . LEU C 3  387 ? -9.044  1.453   -0.342  1.00 29.47 ? 379  LEU I CD2 1 
ATOM   5409 N N   . PHE C 3  388 ? -4.289  1.874   -2.824  1.00 22.47 ? 380  PHE I N   1 
ATOM   5410 C CA  . PHE C 3  388 ? -2.953  1.462   -3.240  1.00 22.86 ? 380  PHE I CA  1 
ATOM   5411 C C   . PHE C 3  388 ? -2.230  2.562   -3.996  1.00 22.72 ? 380  PHE I C   1 
ATOM   5412 O O   . PHE C 3  388 ? -2.849  3.367   -4.693  1.00 21.26 ? 380  PHE I O   1 
ATOM   5413 C CB  . PHE C 3  388 ? -3.029  0.230   -4.140  1.00 22.92 ? 380  PHE I CB  1 
ATOM   5414 C CG  . PHE C 3  388 ? -3.576  -0.986  -3.460  1.00 24.07 ? 380  PHE I CG  1 
ATOM   5415 C CD1 . PHE C 3  388 ? -2.763  -1.765  -2.640  1.00 23.57 ? 380  PHE I CD1 1 
ATOM   5416 C CD2 . PHE C 3  388 ? -4.906  -1.354  -3.633  1.00 23.87 ? 380  PHE I CD2 1 
ATOM   5417 C CE1 . PHE C 3  388 ? -3.268  -2.893  -2.004  1.00 23.29 ? 380  PHE I CE1 1 
ATOM   5418 C CE2 . PHE C 3  388 ? -5.422  -2.482  -3.000  1.00 25.96 ? 380  PHE I CE2 1 
ATOM   5419 C CZ  . PHE C 3  388 ? -4.601  -3.253  -2.183  1.00 25.88 ? 380  PHE I CZ  1 
ATOM   5420 N N   . LEU C 3  389 ? -0.911  2.581   -3.850  1.00 22.61 ? 381  LEU I N   1 
ATOM   5421 C CA  . LEU C 3  389 ? -0.061  3.551   -4.525  1.00 23.66 ? 381  LEU I CA  1 
ATOM   5422 C C   . LEU C 3  389 ? 1.272   2.874   -4.794  1.00 23.70 ? 381  LEU I C   1 
ATOM   5423 O O   . LEU C 3  389 ? 1.840   2.231   -3.911  1.00 23.24 ? 381  LEU I O   1 
ATOM   5424 C CB  . LEU C 3  389 ? 0.168   4.785   -3.653  1.00 23.03 ? 381  LEU I CB  1 
ATOM   5425 C CG  . LEU C 3  389 ? 1.258   5.740   -4.154  1.00 24.62 ? 381  LEU I CG  1 
ATOM   5426 C CD1 . LEU C 3  389 ? 0.870   6.315   -5.517  1.00 23.98 ? 381  LEU I CD1 1 
ATOM   5427 C CD2 . LEU C 3  389 ? 1.459   6.851   -3.142  1.00 25.43 ? 381  LEU I CD2 1 
ATOM   5428 N N   . GLY C 3  390 ? 1.774   3.008   -6.012  1.00 23.86 ? 382  GLY I N   1 
ATOM   5429 C CA  . GLY C 3  390 ? 3.043   2.379   -6.311  1.00 24.97 ? 382  GLY I CA  1 
ATOM   5430 C C   . GLY C 3  390 ? 3.626   2.774   -7.645  1.00 26.06 ? 382  GLY I C   1 
ATOM   5431 O O   . GLY C 3  390 ? 3.040   3.561   -8.389  1.00 24.11 ? 382  GLY I O   1 
ATOM   5432 N N   . LYS C 3  391 ? 4.799   2.221   -7.932  1.00 25.43 ? 383  LYS I N   1 
ATOM   5433 C CA  . LYS C 3  391 ? 5.497   2.474   -9.177  1.00 25.00 ? 383  LYS I CA  1 
ATOM   5434 C C   . LYS C 3  391 ? 5.827   1.132   -9.807  1.00 26.80 ? 383  LYS I C   1 
ATOM   5435 O O   . LYS C 3  391 ? 6.491   0.291   -9.194  1.00 25.72 ? 383  LYS I O   1 
ATOM   5436 C CB  . LYS C 3  391 ? 6.786   3.260   -8.923  1.00 25.64 ? 383  LYS I CB  1 
ATOM   5437 C CG  . LYS C 3  391 ? 7.594   3.532   -10.189 1.00 27.07 ? 383  LYS I CG  1 
ATOM   5438 C CD  . LYS C 3  391 ? 8.774   4.447   -9.928  1.00 26.42 ? 383  LYS I CD  1 
ATOM   5439 C CE  . LYS C 3  391 ? 9.786   3.814   -8.983  1.00 28.72 ? 383  LYS I CE  1 
ATOM   5440 N NZ  . LYS C 3  391 ? 10.932  4.732   -8.737  1.00 26.90 ? 383  LYS I NZ  1 
ATOM   5441 N N   . VAL C 3  392 ? 5.340   0.921   -11.023 1.00 27.45 ? 384  VAL I N   1 
ATOM   5442 C CA  . VAL C 3  392 ? 5.598   -0.320  -11.731 1.00 27.47 ? 384  VAL I CA  1 
ATOM   5443 C C   . VAL C 3  392 ? 6.836   -0.095  -12.585 1.00 30.26 ? 384  VAL I C   1 
ATOM   5444 O O   . VAL C 3  392 ? 6.756   0.430   -13.697 1.00 29.01 ? 384  VAL I O   1 
ATOM   5445 C CB  . VAL C 3  392 ? 4.407   -0.715  -12.625 1.00 27.78 ? 384  VAL I CB  1 
ATOM   5446 C CG1 . VAL C 3  392 ? 4.679   -2.050  -13.301 1.00 27.08 ? 384  VAL I CG1 1 
ATOM   5447 C CG2 . VAL C 3  392 ? 3.140   -0.798  -11.789 1.00 27.33 ? 384  VAL I CG2 1 
ATOM   5448 N N   . ASN C 3  393 ? 7.984   -0.479  -12.039 1.00 31.05 ? 385  ASN I N   1 
ATOM   5449 C CA  . ASN C 3  393 ? 9.257   -0.322  -12.722 1.00 33.69 ? 385  ASN I CA  1 
ATOM   5450 C C   . ASN C 3  393 ? 9.492   -1.515  -13.637 1.00 33.90 ? 385  ASN I C   1 
ATOM   5451 O O   . ASN C 3  393 ? 10.189  -1.413  -14.646 1.00 33.90 ? 385  ASN I O   1 
ATOM   5452 C CB  . ASN C 3  393 ? 10.388  -0.230  -11.699 1.00 36.08 ? 385  ASN I CB  1 
ATOM   5453 C CG  . ASN C 3  393 ? 11.613  0.454   -12.251 1.00 38.49 ? 385  ASN I CG  1 
ATOM   5454 O OD1 . ASN C 3  393 ? 11.602  1.660   -12.500 1.00 40.67 ? 385  ASN I OD1 1 
ATOM   5455 N ND2 . ASN C 3  393 ? 12.682  -0.312  -12.452 1.00 40.71 ? 385  ASN I ND2 1 
ATOM   5456 N N   . ARG C 3  394 ? 8.901   -2.648  -13.273 1.00 35.13 ? 386  ARG I N   1 
ATOM   5457 C CA  . ARG C 3  394 ? 9.034   -3.867  -14.054 1.00 36.09 ? 386  ARG I CA  1 
ATOM   5458 C C   . ARG C 3  394 ? 7.863   -4.801  -13.765 1.00 37.02 ? 386  ARG I C   1 
ATOM   5459 O O   . ARG C 3  394 ? 7.825   -5.463  -12.726 1.00 36.98 ? 386  ARG I O   1 
ATOM   5460 C CB  . ARG C 3  394 ? 10.354  -4.566  -13.722 1.00 36.81 ? 386  ARG I CB  1 
ATOM   5461 C CG  . ARG C 3  394 ? 10.640  -5.787  -14.580 1.00 38.18 ? 386  ARG I CG  1 
ATOM   5462 N N   . PRO C 3  395 ? 6.885   -4.857  -14.682 1.00 37.15 ? 387  PRO I N   1 
ATOM   5463 C CA  . PRO C 3  395 ? 5.690   -5.698  -14.567 1.00 37.76 ? 387  PRO I CA  1 
ATOM   5464 C C   . PRO C 3  395 ? 6.008   -7.158  -14.254 1.00 39.08 ? 387  PRO I C   1 
ATOM   5465 O O   . PRO C 3  395 ? 5.406   -7.693  -13.301 1.00 39.57 ? 387  PRO I O   1 
ATOM   5466 C CB  . PRO C 3  395 ? 5.023   -5.530  -15.930 1.00 37.77 ? 387  PRO I CB  1 
ATOM   5467 C CG  . PRO C 3  395 ? 5.376   -4.125  -16.288 1.00 37.09 ? 387  PRO I CG  1 
ATOM   5468 C CD  . PRO C 3  395 ? 6.839   -4.062  -15.923 1.00 36.74 ? 387  PRO I CD  1 
ATOM   5469 O OXT . PRO C 3  395 ? 6.846   -7.748  -14.970 1.00 39.99 ? 387  PRO I OXT 1 
HETATM 5470 C C1  . NAG D 4  .   ? -17.025 23.908  -24.654 1.00 50.92 ? 778  NAG H C1  1 
HETATM 5471 C C2  . NAG D 4  .   ? -18.162 23.857  -23.627 1.00 52.98 ? 778  NAG H C2  1 
HETATM 5472 C C3  . NAG D 4  .   ? -18.521 25.278  -23.176 1.00 54.78 ? 778  NAG H C3  1 
HETATM 5473 C C4  . NAG D 4  .   ? -17.273 26.012  -22.681 1.00 55.85 ? 778  NAG H C4  1 
HETATM 5474 C C5  . NAG D 4  .   ? -16.155 25.945  -23.728 1.00 56.62 ? 778  NAG H C5  1 
HETATM 5475 C C6  . NAG D 4  .   ? -14.856 26.522  -23.200 1.00 59.56 ? 778  NAG H C6  1 
HETATM 5476 C C7  . NAG D 4  .   ? -20.404 22.988  -23.466 1.00 54.25 ? 778  NAG H C7  1 
HETATM 5477 C C8  . NAG D 4  .   ? -21.649 23.789  -23.809 1.00 54.03 ? 778  NAG H C8  1 
HETATM 5478 N N2  . NAG D 4  .   ? -19.321 23.204  -24.205 1.00 54.27 ? 778  NAG H N2  1 
HETATM 5479 O O3  . NAG D 4  .   ? -19.479 25.222  -22.129 1.00 54.82 ? 778  NAG H O3  1 
HETATM 5480 O O4  . NAG D 4  .   ? -17.591 27.369  -22.412 1.00 57.06 ? 778  NAG H O4  1 
HETATM 5481 O O5  . NAG D 4  .   ? -15.887 24.571  -24.089 1.00 53.98 ? 778  NAG H O5  1 
HETATM 5482 O O6  . NAG D 4  .   ? -14.302 25.632  -22.209 1.00 63.97 ? 778  NAG H O6  1 
HETATM 5483 O O7  . NAG D 4  .   ? -20.426 22.187  -22.531 1.00 54.76 ? 778  NAG H O7  1 
HETATM 5484 C C1  . FUC E 5  .   ? -13.186 26.175  -21.562 1.00 66.20 ? 780  FUC H C1  1 
HETATM 5485 C C2  . FUC E 5  .   ? -12.791 25.282  -20.378 1.00 67.32 ? 780  FUC H C2  1 
HETATM 5486 C C3  . FUC E 5  .   ? -12.213 23.956  -20.880 1.00 68.13 ? 780  FUC H C3  1 
HETATM 5487 C C4  . FUC E 5  .   ? -11.060 24.215  -21.852 1.00 68.46 ? 780  FUC H C4  1 
HETATM 5488 C C5  . FUC E 5  .   ? -11.532 25.129  -22.986 1.00 68.14 ? 780  FUC H C5  1 
HETATM 5489 C C6  . FUC E 5  .   ? -10.407 25.517  -23.926 1.00 68.22 ? 780  FUC H C6  1 
HETATM 5490 O O2  . FUC E 5  .   ? -13.930 25.029  -19.568 1.00 67.96 ? 780  FUC H O2  1 
HETATM 5491 O O3  . FUC E 5  .   ? -11.750 23.188  -19.779 1.00 68.74 ? 780  FUC H O3  1 
HETATM 5492 O O4  . FUC E 5  .   ? -9.981  24.828  -21.161 1.00 69.25 ? 780  FUC H O4  1 
HETATM 5493 O O5  . FUC E 5  .   ? -12.074 26.354  -22.442 1.00 67.30 ? 780  FUC H O5  1 
HETATM 5494 C C1  . SGN F 6  .   ? -38.492 25.158  -33.443 1.00 73.13 ? 1    SGN H C1  1 
HETATM 5495 C C2  . SGN F 6  .   ? -38.091 24.971  -31.989 1.00 73.40 ? 1    SGN H C2  1 
HETATM 5496 C C3  . SGN F 6  .   ? -37.860 26.333  -31.355 1.00 72.62 ? 1    SGN H C3  1 
HETATM 5497 C C4  . SGN F 6  .   ? -36.846 27.118  -32.171 1.00 71.78 ? 1    SGN H C4  1 
HETATM 5498 C C5  . SGN F 6  .   ? -37.299 27.179  -33.621 1.00 71.03 ? 1    SGN H C5  1 
HETATM 5499 C C6  . SGN F 6  .   ? -36.275 27.935  -34.450 1.00 69.41 ? 1    SGN H C6  1 
HETATM 5500 N N   . SGN F 6  .   ? -39.120 24.230  -31.244 1.00 75.50 ? 1    SGN H N   1 
HETATM 5501 O O1  . SGN F 6  .   ? -39.706 25.922  -33.512 1.00 73.34 ? 1    SGN H O1  1 
HETATM 5502 O O3  . SGN F 6  .   ? -37.362 26.160  -30.020 1.00 72.24 ? 1    SGN H O3  1 
HETATM 5503 O O5  . SGN F 6  .   ? -37.448 25.850  -34.144 1.00 72.28 ? 1    SGN H O5  1 
HETATM 5504 O O6  . SGN F 6  .   ? -36.706 27.989  -35.813 1.00 65.60 ? 1    SGN H O6  1 
HETATM 5505 S S1  . SGN F 6  .   ? -39.612 22.928  -32.094 1.00 76.77 ? 1    SGN H S1  1 
HETATM 5506 O O1S . SGN F 6  .   ? -40.296 21.936  -31.152 1.00 76.55 ? 1    SGN H O1S 1 
HETATM 5507 O O2S . SGN F 6  .   ? -40.602 23.361  -33.178 1.00 76.81 ? 1    SGN H O2S 1 
HETATM 5508 O O3S . SGN F 6  .   ? -38.397 22.258  -32.738 1.00 76.93 ? 1    SGN H O3S 1 
HETATM 5509 C C1  . IDS G 7  .   ? -35.384 28.800  -31.376 1.00 72.57 ? 2    IDS H C1  1 
HETATM 5510 C C2  . IDS G 7  .   ? -35.311 30.284  -31.052 1.00 73.05 ? 2    IDS H C2  1 
HETATM 5511 C C3  . IDS G 7  .   ? -33.994 30.580  -30.355 1.00 72.67 ? 2    IDS H C3  1 
HETATM 5512 C C4  . IDS G 7  .   ? -33.997 29.876  -29.008 1.00 71.93 ? 2    IDS H C4  1 
HETATM 5513 C C5  . IDS G 7  .   ? -34.989 28.724  -29.049 1.00 72.03 ? 2    IDS H C5  1 
HETATM 5514 C C6  . IDS G 7  .   ? -34.700 27.768  -27.890 1.00 72.14 ? 2    IDS H C6  1 
HETATM 5515 O O1  . IDS G 7  .   ? -36.749 28.449  -31.642 1.00 72.50 ? 2    IDS H O1  1 
HETATM 5516 O O2  . IDS G 7  .   ? -35.437 31.049  -32.260 1.00 74.56 ? 2    IDS H O2  1 
HETATM 5517 O O3  . IDS G 7  .   ? -33.870 31.996  -30.151 1.00 72.33 ? 2    IDS H O3  1 
HETATM 5518 O O5  . IDS G 7  .   ? -34.849 28.022  -30.292 1.00 72.51 ? 2    IDS H O5  1 
HETATM 5519 O O61 . IDS G 7  .   ? -33.855 26.872  -28.095 1.00 72.42 ? 2    IDS H O61 1 
HETATM 5520 O O62 . IDS G 7  .   ? -35.312 27.972  -26.818 1.00 72.14 ? 2    IDS H O62 1 
HETATM 5521 S S   . IDS G 7  .   ? -36.727 31.520  -32.677 1.00 76.62 ? 2    IDS H S   1 
HETATM 5522 O O1S . IDS G 7  .   ? -36.561 32.483  -33.854 1.00 76.32 ? 2    IDS H O1S 1 
HETATM 5523 O O2S . IDS G 7  .   ? -37.591 30.334  -33.108 1.00 75.85 ? 2    IDS H O2S 1 
HETATM 5524 O O3S . IDS G 7  .   ? -37.403 32.248  -31.513 1.00 76.15 ? 2    IDS H O3S 1 
HETATM 5525 S S   . SO4 H 8  .   ? -44.949 17.143  -42.164 0.87 77.55 ? 781  SO4 H S   1 
HETATM 5526 O O1  . SO4 H 8  .   ? -44.093 16.157  -42.849 1.00 77.36 ? 781  SO4 H O1  1 
HETATM 5527 O O2  . SO4 H 8  .   ? -44.356 17.494  -40.859 1.00 77.41 ? 781  SO4 H O2  1 
HETATM 5528 O O3  . SO4 H 8  .   ? -45.060 18.355  -42.997 0.86 77.74 ? 781  SO4 H O3  1 
HETATM 5529 O O4  . SO4 H 8  .   ? -46.289 16.563  -41.953 0.74 77.68 ? 781  SO4 H O4  1 
HETATM 5530 C C1  . GOL I 9  .   ? -40.823 15.653  -45.406 1.00 25.11 ? 782  GOL H C1  1 
HETATM 5531 O O1  . GOL I 9  .   ? -40.859 16.494  -44.249 1.00 24.85 ? 782  GOL H O1  1 
HETATM 5532 C C2  . GOL I 9  .   ? -41.557 14.341  -45.121 0.74 25.37 ? 782  GOL H C2  1 
HETATM 5533 O O2  . GOL I 9  .   ? -42.888 14.628  -44.687 0.70 27.31 ? 782  GOL H O2  1 
HETATM 5534 C C3  . GOL I 9  .   ? -40.827 13.543  -44.037 0.76 24.71 ? 782  GOL H C3  1 
HETATM 5535 O O3  . GOL I 9  .   ? -39.548 13.117  -44.517 1.00 20.87 ? 782  GOL H O3  1 
HETATM 5536 C C1  . GOL J 9  .   ? -1.843  22.604  -56.364 1.00 49.19 ? 3    GOL H C1  1 
HETATM 5537 O O1  . GOL J 9  .   ? -3.210  22.468  -55.967 0.75 50.82 ? 3    GOL H O1  1 
HETATM 5538 C C2  . GOL J 9  .   ? -1.405  21.344  -57.113 0.55 49.80 ? 3    GOL H C2  1 
HETATM 5539 O O2  . GOL J 9  .   ? -1.540  20.210  -56.252 1.00 48.33 ? 3    GOL H O2  1 
HETATM 5540 C C3  . GOL J 9  .   ? 0.055   21.489  -57.548 0.95 49.57 ? 3    GOL H C3  1 
HETATM 5541 O O3  . GOL J 9  .   ? 0.454   20.324  -58.275 0.60 49.64 ? 3    GOL H O3  1 
HETATM 5542 C C1  . GOL K 9  .   ? -17.536 40.906  -39.659 0.82 55.88 ? 4    GOL H C1  1 
HETATM 5543 O O1  . GOL K 9  .   ? -18.765 40.463  -39.077 1.00 55.24 ? 4    GOL H O1  1 
HETATM 5544 C C2  . GOL K 9  .   ? -17.367 40.272  -41.042 1.00 55.42 ? 4    GOL H C2  1 
HETATM 5545 O O2  . GOL K 9  .   ? -17.356 38.848  -40.917 0.96 55.31 ? 4    GOL H O2  1 
HETATM 5546 C C3  . GOL K 9  .   ? -16.053 40.742  -41.671 0.99 55.44 ? 4    GOL H C3  1 
HETATM 5547 O O3  . GOL K 9  .   ? -14.952 40.334  -40.854 0.83 55.15 ? 4    GOL H O3  1 
HETATM 5548 S S   . SO4 L 8  .   ? -0.070  9.018   -31.640 0.76 70.55 ? 388  SO4 I S   1 
HETATM 5549 O O1  . SO4 L 8  .   ? -1.187  8.054   -31.636 1.00 70.65 ? 388  SO4 I O1  1 
HETATM 5550 O O2  . SO4 L 8  .   ? -0.035  9.725   -32.934 0.70 70.97 ? 388  SO4 I O2  1 
HETATM 5551 O O3  . SO4 L 8  .   ? -0.261  9.996   -30.552 0.71 71.15 ? 388  SO4 I O3  1 
HETATM 5552 O O4  . SO4 L 8  .   ? 1.202   8.298   -31.437 1.00 70.75 ? 388  SO4 I O4  1 
HETATM 5553 S S   . SO4 M 8  .   ? -2.051  -18.886 15.712  0.34 76.50 ? 389  SO4 I S   1 
HETATM 5554 O O1  . SO4 M 8  .   ? -1.529  -20.112 15.078  0.71 76.51 ? 389  SO4 I O1  1 
HETATM 5555 O O2  . SO4 M 8  .   ? -3.448  -18.673 15.291  0.94 76.27 ? 389  SO4 I O2  1 
HETATM 5556 O O3  . SO4 M 8  .   ? -1.995  -19.030 17.179  0.96 76.29 ? 389  SO4 I O3  1 
HETATM 5557 O O4  . SO4 M 8  .   ? -1.230  -17.732 15.301  1.00 76.27 ? 389  SO4 I O4  1 
HETATM 5558 C C1  . GOL N 9  .   ? -22.349 6.986   -33.409 1.00 44.08 ? 390  GOL I C1  1 
HETATM 5559 O O1  . GOL N 9  .   ? -21.231 6.398   -34.079 1.00 44.31 ? 390  GOL I O1  1 
HETATM 5560 C C2  . GOL N 9  .   ? -22.277 6.661   -31.916 0.93 45.24 ? 390  GOL I C2  1 
HETATM 5561 O O2  . GOL N 9  .   ? -22.329 5.244   -31.732 0.68 45.35 ? 390  GOL I O2  1 
HETATM 5562 C C3  . GOL N 9  .   ? -23.456 7.316   -31.193 0.72 45.86 ? 390  GOL I C3  1 
HETATM 5563 O O3  . GOL N 9  .   ? -23.385 7.018   -29.796 0.92 46.39 ? 390  GOL I O3  1 
HETATM 5564 C C1  . GOL O 9  .   ? -2.452  11.583  6.030   1.00 60.91 ? 391  GOL I C1  1 
HETATM 5565 O O1  . GOL O 9  .   ? -1.184  12.009  6.536   1.00 61.17 ? 391  GOL I O1  1 
HETATM 5566 C C2  . GOL O 9  .   ? -2.258  10.359  5.132   1.00 60.78 ? 391  GOL I C2  1 
HETATM 5567 O O2  . GOL O 9  .   ? -1.384  10.693  4.051   1.00 60.80 ? 391  GOL I O2  1 
HETATM 5568 C C3  . GOL O 9  .   ? -3.613  9.912   4.579   1.00 60.91 ? 391  GOL I C3  1 
HETATM 5569 O O3  . GOL O 9  .   ? -3.432  8.776   3.728   0.95 61.46 ? 391  GOL I O3  1 
HETATM 5570 O O   . HOH P 10 .   ? -34.451 18.796  -56.434 1.00 13.70 ? 17   HOH L O   1 
HETATM 5571 O O   . HOH P 10 .   ? -27.745 23.943  -64.533 1.00 16.80 ? 18   HOH L O   1 
HETATM 5572 O O   . HOH P 10 .   ? -29.098 39.361  -47.596 0.95 18.11 ? 19   HOH L O   1 
HETATM 5573 O O   . HOH P 10 .   ? -26.628 38.840  -48.709 1.00 13.91 ? 20   HOH L O   1 
HETATM 5574 O O   . HOH P 10 .   ? -30.846 32.319  -48.869 0.98 13.68 ? 21   HOH L O   1 
HETATM 5575 O O   . HOH P 10 .   ? -29.495 38.850  -41.651 1.00 17.00 ? 22   HOH L O   1 
HETATM 5576 O O   . HOH P 10 .   ? -24.172 34.584  -54.382 0.98 19.10 ? 24   HOH L O   1 
HETATM 5577 O O   . HOH P 10 .   ? -25.550 38.263  -54.370 0.98 16.85 ? 25   HOH L O   1 
HETATM 5578 O O   . HOH P 10 .   ? -29.221 36.629  -59.185 0.99 18.84 ? 26   HOH L O   1 
HETATM 5579 O O   . HOH P 10 .   ? -27.407 39.857  -51.210 0.93 16.94 ? 27   HOH L O   1 
HETATM 5580 O O   . HOH P 10 .   ? -36.442 10.935  -61.018 0.96 21.36 ? 28   HOH L O   1 
HETATM 5581 O O   . HOH P 10 .   ? -25.019 40.060  -52.238 1.00 23.13 ? 29   HOH L O   1 
HETATM 5582 O O   . HOH P 10 .   ? -19.423 23.290  -66.331 1.00 22.06 ? 30   HOH L O   1 
HETATM 5583 O O   . HOH P 10 .   ? -29.153 16.389  -66.130 0.99 21.34 ? 31   HOH L O   1 
HETATM 5584 O O   . HOH P 10 .   ? -31.725 38.485  -56.655 0.95 21.23 ? 32   HOH L O   1 
HETATM 5585 O O   . HOH P 10 .   ? -15.702 28.815  -67.641 0.99 26.88 ? 33   HOH L O   1 
HETATM 5586 O O   . HOH P 10 .   ? -30.251 12.873  -64.973 1.00 31.11 ? 34   HOH L O   1 
HETATM 5587 O O   . HOH P 10 .   ? -22.977 37.271  -54.932 0.99 20.26 ? 35   HOH L O   1 
HETATM 5588 O O   . HOH P 10 .   ? -26.262 39.782  -56.513 0.89 19.75 ? 36   HOH L O   1 
HETATM 5589 O O   . HOH P 10 .   ? -17.642 24.631  -67.869 1.00 23.86 ? 37   HOH L O   1 
HETATM 5590 O O   . HOH P 10 .   ? -29.671 10.573  -62.892 0.95 33.03 ? 38   HOH L O   1 
HETATM 5591 O O   . HOH P 10 .   ? -19.653 31.778  -65.096 1.00 28.49 ? 39   HOH L O   1 
HETATM 5592 O O   . HOH P 10 .   ? -32.574 21.110  -64.402 0.93 30.87 ? 40   HOH L O   1 
HETATM 5593 O O   . HOH P 10 .   ? -20.311 21.085  -67.827 0.96 24.83 ? 41   HOH L O   1 
HETATM 5594 O O   . HOH P 10 .   ? -40.786 18.813  -63.311 0.83 26.00 ? 42   HOH L O   1 
HETATM 5595 O O   . HOH P 10 .   ? -35.086 40.885  -52.787 0.92 29.41 ? 43   HOH L O   1 
HETATM 5596 O O   . HOH P 10 .   ? -22.644 36.729  -57.559 1.00 28.35 ? 44   HOH L O   1 
HETATM 5597 O O   . HOH P 10 .   ? -29.143 14.888  -68.088 0.97 29.98 ? 46   HOH L O   1 
HETATM 5598 O O   . HOH P 10 .   ? -37.055 39.167  -44.106 0.90 25.53 ? 47   HOH L O   1 
HETATM 5599 O O   . HOH P 10 .   ? -32.607 19.073  -66.404 0.94 30.83 ? 48   HOH L O   1 
HETATM 5600 O O   . HOH P 10 .   ? -43.520 12.901  -58.221 0.89 35.22 ? 49   HOH L O   1 
HETATM 5601 O O   . HOH P 10 .   ? -35.671 34.237  -49.746 0.92 30.75 ? 50   HOH L O   1 
HETATM 5602 O O   . HOH P 10 .   ? -38.375 37.807  -48.050 0.90 33.22 ? 51   HOH L O   1 
HETATM 5603 O O   . HOH P 10 .   ? -21.445 38.895  -53.368 0.87 27.14 ? 52   HOH L O   1 
HETATM 5604 O O   . HOH P 10 .   ? -28.880 46.352  -45.553 0.97 29.45 ? 53   HOH L O   1 
HETATM 5605 O O   . HOH P 10 .   ? -33.548 38.143  -58.679 0.93 29.00 ? 54   HOH L O   1 
HETATM 5606 O O   . HOH P 10 .   ? -37.990 33.204  -61.637 1.00 37.17 ? 55   HOH L O   1 
HETATM 5607 O O   . HOH P 10 .   ? -28.039 39.078  -58.366 0.85 30.65 ? 56   HOH L O   1 
HETATM 5608 O O   . HOH P 10 .   ? -21.569 27.815  -71.935 1.00 43.06 ? 57   HOH L O   1 
HETATM 5609 O O   . HOH P 10 .   ? -31.910 43.412  -40.284 0.88 33.78 ? 58   HOH L O   1 
HETATM 5610 O O   . HOH P 10 .   ? -32.953 40.021  -54.688 1.00 40.72 ? 59   HOH L O   1 
HETATM 5611 O O   . HOH P 10 .   ? -33.863 38.918  -41.872 0.95 41.20 ? 60   HOH L O   1 
HETATM 5612 O O   . HOH P 10 .   ? -36.831 41.320  -50.494 1.00 53.06 ? 61   HOH L O   1 
HETATM 5613 O O   . HOH P 10 .   ? -30.398 41.422  -48.965 0.75 33.72 ? 62   HOH L O   1 
HETATM 5614 O O   . HOH P 10 .   ? -25.667 31.528  -70.084 1.00 38.10 ? 63   HOH L O   1 
HETATM 5615 O O   . HOH P 10 .   ? -22.664 20.351  -68.793 0.86 29.50 ? 64   HOH L O   1 
HETATM 5616 O O   . HOH P 10 .   ? -34.873 19.683  -67.577 1.00 40.70 ? 65   HOH L O   1 
HETATM 5617 O O   . HOH P 10 .   ? -20.653 30.527  -71.522 1.00 48.95 ? 66   HOH L O   1 
HETATM 5618 O O   . HOH P 10 .   ? -18.550 31.291  -70.000 1.00 46.23 ? 67   HOH L O   1 
HETATM 5619 O O   . HOH P 10 .   ? -30.563 40.427  -58.027 0.94 36.75 ? 68   HOH L O   1 
HETATM 5620 O O   . HOH P 10 .   ? -33.039 11.370  -65.941 1.00 48.51 ? 69   HOH L O   1 
HETATM 5621 O O   . HOH P 10 .   ? -23.964 30.930  -72.323 0.97 53.84 ? 70   HOH L O   1 
HETATM 5622 O O   . HOH P 10 .   ? -27.735 32.708  -66.743 1.00 43.74 ? 71   HOH L O   1 
HETATM 5623 O O   . HOH P 10 .   ? -36.303 10.098  -63.569 0.90 34.62 ? 72   HOH L O   1 
HETATM 5624 O O   . HOH P 10 .   ? -38.839 10.202  -59.811 0.93 44.69 ? 73   HOH L O   1 
HETATM 5625 O O   . HOH P 10 .   ? -39.249 38.480  -45.511 0.81 37.23 ? 74   HOH L O   1 
HETATM 5626 O O   . HOH P 10 .   ? -29.085 8.941   -59.354 0.82 43.06 ? 75   HOH L O   1 
HETATM 5627 O O   . HOH P 10 .   ? -18.988 39.073  -52.557 0.70 37.92 ? 76   HOH L O   1 
HETATM 5628 O O   . HOH P 10 .   ? -33.995 42.064  -41.400 0.84 52.45 ? 77   HOH L O   1 
HETATM 5629 O O   . HOH P 10 .   ? -32.102 37.817  -60.970 1.00 59.66 ? 78   HOH L O   1 
HETATM 5630 O O   . HOH P 10 .   ? -32.564 9.163   -64.290 1.00 63.10 ? 79   HOH L O   1 
HETATM 5631 O O   . HOH P 10 .   ? -30.563 35.239  -67.884 1.00 50.99 ? 80   HOH L O   1 
HETATM 5632 O O   . HOH P 10 .   ? -30.045 36.295  -61.990 0.94 32.53 ? 81   HOH L O   1 
HETATM 5633 O O   . HOH P 10 .   ? -39.569 34.637  -50.798 0.95 38.61 ? 82   HOH L O   1 
HETATM 5634 O O   . HOH P 10 .   ? -33.791 41.142  -47.262 0.99 26.62 ? 83   HOH L O   1 
HETATM 5635 O O   . HOH P 10 .   ? -26.417 21.301  -70.574 0.98 31.51 ? 84   HOH L O   1 
HETATM 5636 O O   . HOH P 10 .   ? -25.562 16.872  -68.713 1.00 42.96 ? 85   HOH L O   1 
HETATM 5637 O O   . HOH P 10 .   ? -27.778 17.597  -69.753 1.00 43.30 ? 86   HOH L O   1 
HETATM 5638 O O   . HOH P 10 .   ? -21.739 44.348  -41.498 0.97 25.29 ? 87   HOH L O   1 
HETATM 5639 O O   . HOH P 10 .   ? -28.981 42.066  -51.303 1.00 28.01 ? 89   HOH L O   1 
HETATM 5640 O O   . HOH P 10 .   ? -25.744 39.096  -60.825 1.00 49.11 ? 91   HOH L O   1 
HETATM 5641 O O   . HOH P 10 .   ? -23.740 36.905  -62.862 1.00 48.09 ? 92   HOH L O   1 
HETATM 5642 O O   . HOH P 10 .   ? -20.926 33.296  -67.255 1.00 49.86 ? 93   HOH L O   1 
HETATM 5643 O O   . HOH P 10 .   ? -22.496 26.480  -74.007 1.00 46.62 ? 94   HOH L O   1 
HETATM 5644 O O   . HOH P 10 .   ? -31.567 43.888  -47.952 1.00 33.44 ? 95   HOH L O   1 
HETATM 5645 O O   . HOH P 10 .   ? -23.220 41.270  -53.263 0.96 30.60 ? 96   HOH L O   1 
HETATM 5646 O O   . HOH P 10 .   ? -20.200 41.213  -53.232 0.28 70.92 ? 97   HOH L O   1 
HETATM 5647 O O   . HOH P 10 .   ? -25.149 10.314  -65.488 1.00 46.54 ? 98   HOH L O   1 
HETATM 5648 O O   . HOH P 10 .   ? -43.385 19.499  -62.701 0.89 50.83 ? 99   HOH L O   1 
HETATM 5649 O O   . HOH P 10 .   ? -21.386 42.676  -51.598 0.88 29.32 ? 100  HOH L O   1 
HETATM 5650 O O   . HOH P 10 .   ? -28.814 22.720  -70.950 1.00 58.34 ? 101  HOH L O   1 
HETATM 5651 O O   . HOH P 10 .   ? -41.910 11.346  -61.301 0.98 47.08 ? 102  HOH L O   1 
HETATM 5652 O O   . HOH P 10 .   ? -19.503 31.556  -74.193 0.92 41.94 ? 488  HOH L O   1 
HETATM 5653 O O   . HOH Q 10 .   ? -34.526 4.429   -40.826 1.00 12.54 ? 783  HOH H O   1 
HETATM 5654 O O   . HOH Q 10 .   ? -30.536 9.270   -46.828 1.00 12.96 ? 784  HOH H O   1 
HETATM 5655 O O   . HOH Q 10 .   ? -18.457 10.392  -49.946 0.99 13.68 ? 785  HOH H O   1 
HETATM 5656 O O   . HOH Q 10 .   ? -19.968 26.525  -60.247 1.00 15.41 ? 786  HOH H O   1 
HETATM 5657 O O   . HOH Q 10 .   ? -25.832 18.404  -51.957 0.99 11.01 ? 787  HOH H O   1 
HETATM 5658 O O   . HOH Q 10 .   ? -33.230 18.041  -36.283 1.00 14.03 ? 788  HOH H O   1 
HETATM 5659 O O   . HOH Q 10 .   ? -36.424 22.517  -45.146 1.00 15.24 ? 789  HOH H O   1 
HETATM 5660 O O   . HOH Q 10 .   ? -31.973 15.533  -36.313 1.00 15.04 ? 790  HOH H O   1 
HETATM 5661 O O   . HOH Q 10 .   ? -15.119 22.685  -50.013 1.00 15.09 ? 791  HOH H O   1 
HETATM 5662 O O   . HOH Q 10 .   ? -30.372 4.643   -44.035 1.00 16.12 ? 792  HOH H O   1 
HETATM 5663 O O   . HOH Q 10 .   ? -17.213 24.805  -52.242 1.00 15.42 ? 793  HOH H O   1 
HETATM 5664 O O   . HOH Q 10 .   ? -25.172 22.268  -44.032 0.97 15.02 ? 794  HOH H O   1 
HETATM 5665 O O   . HOH Q 10 .   ? -25.039 20.371  -53.717 1.00 13.47 ? 795  HOH H O   1 
HETATM 5666 O O   . HOH Q 10 .   ? -25.245 20.226  -56.457 1.00 16.87 ? 796  HOH H O   1 
HETATM 5667 O O   . HOH Q 10 .   ? -25.050 41.335  -35.177 1.00 18.87 ? 797  HOH H O   1 
HETATM 5668 O O   . HOH Q 10 .   ? -38.450 6.397   -51.271 1.00 15.65 ? 798  HOH H O   1 
HETATM 5669 O O   . HOH Q 10 .   ? -21.152 16.194  -46.281 1.00 12.93 ? 799  HOH H O   1 
HETATM 5670 O O   . HOH Q 10 .   ? -28.727 2.627   -43.091 1.00 17.30 ? 800  HOH H O   1 
HETATM 5671 O O   . HOH Q 10 .   ? -20.402 7.355   -53.452 1.00 18.99 ? 801  HOH H O   1 
HETATM 5672 O O   . HOH Q 10 .   ? -19.398 32.897  -57.426 1.00 17.18 ? 802  HOH H O   1 
HETATM 5673 O O   . HOH Q 10 .   ? -40.146 8.483   -51.516 1.00 19.19 ? 803  HOH H O   1 
HETATM 5674 O O   . HOH Q 10 .   ? -38.808 0.065   -42.487 1.00 20.32 ? 804  HOH H O   1 
HETATM 5675 O O   . HOH Q 10 .   ? -32.711 5.616   -39.034 1.00 15.99 ? 805  HOH H O   1 
HETATM 5676 O O   . HOH Q 10 .   ? -36.694 32.067  -52.069 1.00 16.44 ? 806  HOH H O   1 
HETATM 5677 O O   . HOH Q 10 .   ? -18.492 15.574  -46.096 1.00 17.18 ? 807  HOH H O   1 
HETATM 5678 O O   . HOH Q 10 .   ? -28.117 32.210  -49.041 0.97 14.70 ? 808  HOH H O   1 
HETATM 5679 O O   . HOH Q 10 .   ? -33.162 4.411   -47.876 0.98 15.36 ? 809  HOH H O   1 
HETATM 5680 O O   . HOH Q 10 .   ? -11.926 30.033  -55.289 1.00 18.68 ? 810  HOH H O   1 
HETATM 5681 O O   . HOH Q 10 .   ? -34.316 1.691   -34.467 0.99 21.11 ? 811  HOH H O   1 
HETATM 5682 O O   . HOH Q 10 .   ? -16.779 23.938  -56.217 1.00 20.41 ? 812  HOH H O   1 
HETATM 5683 O O   . HOH Q 10 .   ? -31.519 4.503   -50.745 0.97 15.23 ? 813  HOH H O   1 
HETATM 5684 O O   . HOH Q 10 .   ? -20.591 3.053   -52.287 1.00 21.42 ? 814  HOH H O   1 
HETATM 5685 O O   . HOH Q 10 .   ? -40.815 2.275   -42.814 1.00 17.40 ? 815  HOH H O   1 
HETATM 5686 O O   . HOH Q 10 .   ? -30.833 6.174   -47.634 1.00 18.65 ? 816  HOH H O   1 
HETATM 5687 O O   . HOH Q 10 .   ? -17.719 21.885  -64.422 1.00 20.77 ? 817  HOH H O   1 
HETATM 5688 O O   . HOH Q 10 .   ? -30.670 5.007   -41.218 1.00 19.89 ? 818  HOH H O   1 
HETATM 5689 O O   . HOH Q 10 .   ? -40.395 6.737   -34.898 1.00 18.88 ? 819  HOH H O   1 
HETATM 5690 O O   . HOH Q 10 .   ? -30.177 41.384  -39.055 1.00 22.32 ? 820  HOH H O   1 
HETATM 5691 O O   . HOH Q 10 .   ? -16.958 22.388  -53.788 0.97 19.55 ? 821  HOH H O   1 
HETATM 5692 O O   . HOH Q 10 .   ? -12.201 32.412  -53.965 0.90 24.55 ? 822  HOH H O   1 
HETATM 5693 O O   . HOH Q 10 .   ? -30.807 2.232   -49.312 1.00 22.48 ? 823  HOH H O   1 
HETATM 5694 O O   . HOH Q 10 .   ? -39.382 19.017  -31.264 0.99 25.91 ? 824  HOH H O   1 
HETATM 5695 O O   . HOH Q 10 .   ? -38.572 28.712  -55.734 1.00 20.28 ? 825  HOH H O   1 
HETATM 5696 O O   . HOH Q 10 .   ? -30.884 2.917   -46.464 1.00 26.78 ? 826  HOH H O   1 
HETATM 5697 O O   . HOH Q 10 .   ? -18.536 21.159  -55.865 0.95 19.56 ? 827  HOH H O   1 
HETATM 5698 O O   . HOH Q 10 .   ? -19.114 39.568  -45.107 0.94 27.72 ? 828  HOH H O   1 
HETATM 5699 O O   . HOH Q 10 .   ? -21.272 13.559  -32.005 0.98 29.20 ? 829  HOH H O   1 
HETATM 5700 O O   . HOH Q 10 .   ? -13.123 22.668  -56.832 1.00 27.13 ? 830  HOH H O   1 
HETATM 5701 O O   . HOH Q 10 .   ? -29.440 -3.977  -45.021 1.00 27.02 ? 831  HOH H O   1 
HETATM 5702 O O   . HOH Q 10 .   ? -45.892 16.492  -58.627 1.00 25.92 ? 832  HOH H O   1 
HETATM 5703 O O   . HOH Q 10 .   ? -26.824 22.777  -27.564 1.00 26.36 ? 833  HOH H O   1 
HETATM 5704 O O   . HOH Q 10 .   ? -20.433 46.697  -38.990 0.98 27.08 ? 834  HOH H O   1 
HETATM 5705 O O   . HOH Q 10 .   ? -36.732 17.227  -28.647 1.00 24.57 ? 835  HOH H O   1 
HETATM 5706 O O   . HOH Q 10 .   ? -36.121 35.002  -35.973 0.96 24.34 ? 836  HOH H O   1 
HETATM 5707 O O   . HOH Q 10 .   ? -30.325 16.980  -24.701 0.95 29.39 ? 837  HOH H O   1 
HETATM 5708 O O   . HOH Q 10 .   ? -17.559 15.275  -34.664 1.00 27.77 ? 838  HOH H O   1 
HETATM 5709 O O   . HOH Q 10 .   ? -10.312 30.867  -57.104 0.93 25.47 ? 839  HOH H O   1 
HETATM 5710 O O   . HOH Q 10 .   ? -11.121 28.473  -36.270 1.00 29.44 ? 840  HOH H O   1 
HETATM 5711 O O   . HOH Q 10 .   ? -38.720 0.447   -36.413 0.95 24.98 ? 841  HOH H O   1 
HETATM 5712 O O   . HOH Q 10 .   ? -39.416 28.755  -40.137 1.00 31.75 ? 842  HOH H O   1 
HETATM 5713 O O   . HOH Q 10 .   ? -36.230 8.731   -29.186 0.90 25.59 ? 843  HOH H O   1 
HETATM 5714 O O   . HOH Q 10 .   ? -30.408 8.132   -57.296 0.96 22.69 ? 844  HOH H O   1 
HETATM 5715 O O   . HOH Q 10 .   ? -28.653 21.203  -26.112 0.99 29.26 ? 845  HOH H O   1 
HETATM 5716 O O   . HOH Q 10 .   ? -18.724 18.770  -47.156 0.91 22.39 ? 846  HOH H O   1 
HETATM 5717 O O   . HOH Q 10 .   ? -27.394 9.745   -57.507 1.00 32.34 ? 847  HOH H O   1 
HETATM 5718 O O   . HOH Q 10 .   ? -16.522 18.443  -22.956 1.00 31.74 ? 848  HOH H O   1 
HETATM 5719 O O   . HOH Q 10 .   ? -48.101 28.966  -53.075 1.00 29.68 ? 849  HOH H O   1 
HETATM 5720 O O   . HOH Q 10 .   ? -29.943 25.422  -65.498 1.00 26.80 ? 850  HOH H O   1 
HETATM 5721 O O   . HOH Q 10 .   ? -16.839 37.875  -50.186 0.95 26.69 ? 851  HOH H O   1 
HETATM 5722 O O   . HOH Q 10 .   ? -16.808 37.686  -53.282 0.94 22.15 ? 852  HOH H O   1 
HETATM 5723 O O   . HOH Q 10 .   ? -15.521 22.034  -57.535 0.93 22.44 ? 853  HOH H O   1 
HETATM 5724 O O   . HOH Q 10 .   ? -41.527 8.963   -34.215 0.92 21.70 ? 854  HOH H O   1 
HETATM 5725 O O   . HOH Q 10 .   ? -39.899 1.230   -45.420 0.86 18.99 ? 855  HOH H O   1 
HETATM 5726 O O   . HOH Q 10 .   ? -42.261 19.364  -44.069 0.96 29.31 ? 856  HOH H O   1 
HETATM 5727 O O   . HOH Q 10 .   ? -11.255 34.320  -49.828 0.95 27.59 ? 857  HOH H O   1 
HETATM 5728 O O   . HOH Q 10 .   ? -42.527 14.025  -36.899 1.00 28.22 ? 858  HOH H O   1 
HETATM 5729 O O   . HOH Q 10 .   ? -35.219 25.242  -63.482 0.96 27.83 ? 859  HOH H O   1 
HETATM 5730 O O   . HOH Q 10 .   ? -30.870 30.862  -64.216 1.00 31.76 ? 860  HOH H O   1 
HETATM 5731 O O   . HOH Q 10 .   ? -13.352 31.714  -60.478 0.95 22.73 ? 861  HOH H O   1 
HETATM 5732 O O   . HOH Q 10 .   ? -38.027 7.394   -56.246 1.00 36.54 ? 862  HOH H O   1 
HETATM 5733 O O   . HOH Q 10 .   ? -19.176 23.132  -29.165 1.00 30.54 ? 863  HOH H O   1 
HETATM 5734 O O   . HOH Q 10 .   ? -15.178 22.577  -65.121 0.86 23.90 ? 864  HOH H O   1 
HETATM 5735 O O   . HOH Q 10 .   ? -23.190 0.748   -46.481 1.00 29.85 ? 865  HOH H O   1 
HETATM 5736 O O   . HOH Q 10 .   ? -40.287 7.653   -54.258 0.99 30.34 ? 866  HOH H O   1 
HETATM 5737 O O   . HOH Q 10 .   ? -27.235 10.527  -26.102 0.92 25.64 ? 867  HOH H O   1 
HETATM 5738 O O   . HOH Q 10 .   ? -24.886 -1.797  -43.937 1.00 30.63 ? 868  HOH H O   1 
HETATM 5739 O O   . HOH Q 10 .   ? -23.368 27.372  -29.060 0.94 25.83 ? 869  HOH H O   1 
HETATM 5740 O O   . HOH Q 10 .   ? -19.026 18.020  -24.238 0.94 27.16 ? 870  HOH H O   1 
HETATM 5741 O O   . HOH Q 10 .   ? -24.866 24.413  -26.548 0.90 29.53 ? 871  HOH H O   1 
HETATM 5742 O O   . HOH Q 10 .   ? -43.031 20.360  -46.794 1.00 37.69 ? 872  HOH H O   1 
HETATM 5743 O O   . HOH Q 10 .   ? -31.040 37.459  -39.801 0.94 24.48 ? 873  HOH H O   1 
HETATM 5744 O O   . HOH Q 10 .   ? -6.484  29.849  -52.822 0.92 31.69 ? 874  HOH H O   1 
HETATM 5745 O O   . HOH Q 10 .   ? -45.364 20.443  -48.467 1.00 33.43 ? 875  HOH H O   1 
HETATM 5746 O O   . HOH Q 10 .   ? -19.186 18.950  -65.812 0.98 30.44 ? 876  HOH H O   1 
HETATM 5747 O O   . HOH Q 10 .   ? -42.464 17.306  -33.894 1.00 35.25 ? 877  HOH H O   1 
HETATM 5748 O O   . HOH Q 10 .   ? -34.014 32.815  -47.796 0.86 25.52 ? 878  HOH H O   1 
HETATM 5749 O O   . HOH Q 10 .   ? -42.981 32.120  -49.358 1.00 30.90 ? 879  HOH H O   1 
HETATM 5750 O O   . HOH Q 10 .   ? -18.265 4.033   -42.599 0.98 35.23 ? 880  HOH H O   1 
HETATM 5751 O O   . HOH Q 10 .   ? -34.777 1.612   -47.308 0.91 31.59 ? 881  HOH H O   1 
HETATM 5752 O O   . HOH Q 10 .   ? -21.667 29.661  -28.921 0.99 35.09 ? 882  HOH H O   1 
HETATM 5753 O O   . HOH Q 10 .   ? -16.152 18.145  -63.938 0.97 29.15 ? 883  HOH H O   1 
HETATM 5754 O O   . HOH Q 10 .   ? -6.082  28.086  -49.374 0.92 35.29 ? 884  HOH H O   1 
HETATM 5755 O O   . HOH Q 10 .   ? -22.541 17.803  -67.350 1.00 33.38 ? 885  HOH H O   1 
HETATM 5756 O O   . HOH Q 10 .   ? -43.641 25.704  -45.807 0.99 30.88 ? 886  HOH H O   1 
HETATM 5757 O O   . HOH Q 10 .   ? -13.759 9.540   -55.911 1.00 34.51 ? 887  HOH H O   1 
HETATM 5758 O O   . HOH Q 10 .   ? -45.309 2.992   -42.968 0.88 37.24 ? 888  HOH H O   1 
HETATM 5759 O O   . HOH Q 10 .   ? -16.484 19.806  -56.870 1.00 32.99 ? 889  HOH H O   1 
HETATM 5760 O O   . HOH Q 10 .   ? -13.403 27.961  -63.945 0.94 35.01 ? 890  HOH H O   1 
HETATM 5761 O O   . HOH Q 10 .   ? -10.839 34.402  -55.086 0.78 36.69 ? 891  HOH H O   1 
HETATM 5762 O O   . HOH Q 10 .   ? -39.037 9.690   -56.913 1.00 34.79 ? 892  HOH H O   1 
HETATM 5763 O O   . HOH Q 10 .   ? -22.512 41.030  -34.024 1.00 28.92 ? 893  HOH H O   1 
HETATM 5764 O O   . HOH Q 10 .   ? -45.127 12.992  -45.350 1.00 30.52 ? 894  HOH H O   1 
HETATM 5765 O O   . HOH Q 10 .   ? -32.600 -0.018  -50.153 0.89 32.78 ? 895  HOH H O   1 
HETATM 5766 O O   . HOH Q 10 .   ? -29.440 26.046  -68.179 1.00 38.12 ? 896  HOH H O   1 
HETATM 5767 O O   . HOH Q 10 .   ? -21.354 4.103   -56.681 0.86 34.00 ? 897  HOH H O   1 
HETATM 5768 O O   . HOH Q 10 .   ? -12.834 35.146  -57.419 0.75 32.45 ? 898  HOH H O   1 
HETATM 5769 O O   . HOH Q 10 .   ? -38.451 35.230  -48.326 0.97 37.53 ? 899  HOH H O   1 
HETATM 5770 O O   . HOH Q 10 .   ? -24.936 10.032  -58.585 1.00 43.18 ? 900  HOH H O   1 
HETATM 5771 O O   . HOH Q 10 .   ? -28.664 43.309  -35.421 1.00 40.09 ? 901  HOH H O   1 
HETATM 5772 O O   . HOH Q 10 .   ? -16.616 17.272  -45.359 0.79 27.52 ? 902  HOH H O   1 
HETATM 5773 O O   . HOH Q 10 .   ? -32.640 39.660  -39.913 0.88 34.17 ? 903  HOH H O   1 
HETATM 5774 O O   . HOH Q 10 .   ? -14.312 12.310  -61.535 0.88 31.99 ? 904  HOH H O   1 
HETATM 5775 O O   . HOH Q 10 .   ? -8.606  13.717  -42.453 1.00 44.74 ? 905  HOH H O   1 
HETATM 5776 O O   . HOH Q 10 .   ? -17.084 33.310  -60.856 1.00 34.41 ? 906  HOH H O   1 
HETATM 5777 O O   . HOH Q 10 .   ? -22.056 14.395  -61.614 0.87 40.72 ? 907  HOH H O   1 
HETATM 5778 O O   . HOH Q 10 .   ? -41.731 22.278  -45.489 0.99 42.20 ? 908  HOH H O   1 
HETATM 5779 O O   . HOH Q 10 .   ? -11.962 11.632  -40.761 1.00 37.70 ? 909  HOH H O   1 
HETATM 5780 O O   . HOH Q 10 .   ? -8.028  13.661  -55.966 0.93 34.60 ? 910  HOH H O   1 
HETATM 5781 O O   . HOH Q 10 .   ? -3.400  21.596  -47.158 1.00 40.19 ? 911  HOH H O   1 
HETATM 5782 O O   . HOH Q 10 .   ? -42.853 8.230   -52.116 0.82 28.61 ? 912  HOH H O   1 
HETATM 5783 O O   . HOH Q 10 .   ? -26.894 -2.555  -46.812 1.00 43.58 ? 913  HOH H O   1 
HETATM 5784 O O   . HOH Q 10 .   ? -28.723 11.506  -20.726 1.00 40.38 ? 914  HOH H O   1 
HETATM 5785 O O   . HOH Q 10 .   ? -41.302 31.067  -53.433 0.96 30.23 ? 915  HOH H O   1 
HETATM 5786 O O   . HOH Q 10 .   ? -25.503 43.916  -34.731 1.00 31.29 ? 916  HOH H O   1 
HETATM 5787 O O   . HOH Q 10 .   ? -45.218 32.204  -55.932 0.98 34.79 ? 917  HOH H O   1 
HETATM 5788 O O   . HOH Q 10 .   ? -10.942 21.632  -58.197 0.92 33.50 ? 918  HOH H O   1 
HETATM 5789 O O   . HOH Q 10 .   ? -28.553 32.074  -64.179 1.00 33.80 ? 919  HOH H O   1 
HETATM 5790 O O   . HOH Q 10 .   ? -18.271 40.939  -47.878 1.00 35.88 ? 920  HOH H O   1 
HETATM 5791 O O   . HOH Q 10 .   ? -32.327 24.671  -66.149 1.00 40.97 ? 921  HOH H O   1 
HETATM 5792 O O   . HOH Q 10 .   ? -14.627 7.143   -54.894 0.92 46.42 ? 922  HOH H O   1 
HETATM 5793 O O   . HOH Q 10 .   ? -18.532 41.475  -34.428 1.00 44.15 ? 923  HOH H O   1 
HETATM 5794 O O   . HOH Q 10 .   ? -41.934 26.576  -39.342 1.00 38.70 ? 924  HOH H O   1 
HETATM 5795 O O   . HOH Q 10 .   ? -25.808 26.870  -27.475 0.87 33.26 ? 925  HOH H O   1 
HETATM 5796 O O   . HOH Q 10 .   ? -44.313 3.236   -48.714 0.76 34.94 ? 926  HOH H O   1 
HETATM 5797 O O   . HOH Q 10 .   ? -28.965 5.757   -56.699 0.91 39.56 ? 927  HOH H O   1 
HETATM 5798 O O   . HOH Q 10 .   ? -42.609 5.508   -52.700 0.98 42.50 ? 928  HOH H O   1 
HETATM 5799 O O   . HOH Q 10 .   ? -3.508  14.956  -39.455 1.00 43.00 ? 929  HOH H O   1 
HETATM 5800 O O   . HOH Q 10 .   ? -7.108  30.444  -47.947 0.91 44.99 ? 930  HOH H O   1 
HETATM 5801 O O   . HOH Q 10 .   ? -19.333 4.591   -54.447 0.90 40.48 ? 931  HOH H O   1 
HETATM 5802 O O   . HOH Q 10 .   ? -14.616 39.348  -53.676 0.82 35.75 ? 932  HOH H O   1 
HETATM 5803 O O   . HOH Q 10 .   ? -8.190  29.277  -60.694 1.00 45.87 ? 933  HOH H O   1 
HETATM 5804 O O   . HOH Q 10 .   ? -13.372 37.646  -36.744 0.83 33.97 ? 934  HOH H O   1 
HETATM 5805 O O   . HOH Q 10 .   ? -3.255  23.906  -45.881 1.00 54.32 ? 935  HOH H O   1 
HETATM 5806 O O   . HOH Q 10 .   ? -40.561 25.420  -36.742 0.87 35.75 ? 936  HOH H O   1 
HETATM 5807 O O   . HOH Q 10 .   ? -11.878 20.040  -28.296 1.00 43.01 ? 937  HOH H O   1 
HETATM 5808 O O   . HOH Q 10 .   ? -5.027  24.422  -58.767 0.85 34.24 ? 938  HOH H O   1 
HETATM 5809 O O   . HOH Q 10 .   ? -23.675 7.884   -25.271 0.96 39.55 ? 939  HOH H O   1 
HETATM 5810 O O   . HOH Q 10 .   ? -40.348 17.141  -29.587 0.92 43.15 ? 940  HOH H O   1 
HETATM 5811 O O   . HOH Q 10 .   ? -20.674 35.629  -29.541 0.93 34.08 ? 941  HOH H O   1 
HETATM 5812 O O   . HOH Q 10 .   ? -22.259 -0.011  -51.548 1.00 51.94 ? 942  HOH H O   1 
HETATM 5813 O O   . HOH Q 10 .   ? -41.935 8.301   -56.143 0.98 41.75 ? 943  HOH H O   1 
HETATM 5814 O O   . HOH Q 10 .   ? -45.888 5.766   -38.663 0.90 32.79 ? 944  HOH H O   1 
HETATM 5815 O O   . HOH Q 10 .   ? -13.822 18.255  -27.748 1.00 42.94 ? 945  HOH H O   1 
HETATM 5816 O O   . HOH Q 10 .   ? -5.839  21.792  -58.252 1.00 42.84 ? 946  HOH H O   1 
HETATM 5817 O O   . HOH Q 10 .   ? -43.164 1.147   -43.286 0.88 36.83 ? 947  HOH H O   1 
HETATM 5818 O O   . HOH Q 10 .   ? -27.320 1.722   -56.195 1.00 52.73 ? 948  HOH H O   1 
HETATM 5819 O O   . HOH Q 10 .   ? -32.342 18.529  -24.458 1.00 51.21 ? 949  HOH H O   1 
HETATM 5820 O O   . HOH Q 10 .   ? -29.624 8.554   -26.661 0.82 38.44 ? 950  HOH H O   1 
HETATM 5821 O O   . HOH Q 10 .   ? -36.900 33.263  -47.774 0.81 33.85 ? 951  HOH H O   1 
HETATM 5822 O O   . HOH Q 10 .   ? -14.526 39.184  -50.092 1.00 47.80 ? 952  HOH H O   1 
HETATM 5823 O O   . HOH Q 10 .   ? -12.927 14.483  -60.793 0.96 40.84 ? 953  HOH H O   1 
HETATM 5824 O O   . HOH Q 10 .   ? -8.650  8.980   -51.662 0.90 45.23 ? 954  HOH H O   1 
HETATM 5825 O O   . HOH Q 10 .   ? -29.317 9.796   -22.940 1.00 43.20 ? 955  HOH H O   1 
HETATM 5826 O O   . HOH Q 10 .   ? -18.004 43.894  -36.201 1.00 58.94 ? 956  HOH H O   1 
HETATM 5827 O O   . HOH Q 10 .   ? -16.133 14.488  -62.133 0.94 40.86 ? 957  HOH H O   1 
HETATM 5828 O O   . HOH Q 10 .   ? -16.481 30.661  -65.770 1.00 46.65 ? 958  HOH H O   1 
HETATM 5829 O O   . HOH Q 10 .   ? -19.411 3.965   -40.176 1.00 48.26 ? 959  HOH H O   1 
HETATM 5830 O O   . HOH Q 10 .   ? -46.598 30.665  -48.704 1.00 40.33 ? 960  HOH H O   1 
HETATM 5831 O O   . HOH Q 10 .   ? -46.009 10.670  -38.923 1.00 44.71 ? 961  HOH H O   1 
HETATM 5832 O O   . HOH Q 10 .   ? -14.074 19.395  -24.170 1.00 60.84 ? 962  HOH H O   1 
HETATM 5833 O O   . HOH Q 10 .   ? -13.271 34.677  -31.907 0.69 46.17 ? 963  HOH H O   1 
HETATM 5834 O O   . HOH Q 10 .   ? -40.826 19.117  -33.553 0.87 37.25 ? 964  HOH H O   1 
HETATM 5835 O O   . HOH Q 10 .   ? -42.515 0.112   -36.901 0.83 38.22 ? 965  HOH H O   1 
HETATM 5836 O O   . HOH Q 10 .   ? -8.117  32.886  -55.769 0.99 54.09 ? 966  HOH H O   1 
HETATM 5837 O O   . HOH Q 10 .   ? -47.041 10.356  -50.827 0.79 42.05 ? 967  HOH H O   1 
HETATM 5838 O O   . HOH Q 10 .   ? -20.812 38.932  -32.558 1.00 53.62 ? 968  HOH H O   1 
HETATM 5839 O O   . HOH Q 10 .   ? -9.810  15.892  -28.948 1.00 45.09 ? 969  HOH H O   1 
HETATM 5840 O O   . HOH Q 10 .   ? -26.101 41.844  -31.181 1.00 45.64 ? 970  HOH H O   1 
HETATM 5841 O O   . HOH Q 10 .   ? -22.512 25.438  -27.216 0.81 38.12 ? 971  HOH H O   1 
HETATM 5842 O O   . HOH Q 10 .   ? -14.383 8.604   -40.374 0.88 36.76 ? 972  HOH H O   1 
HETATM 5843 O O   . HOH Q 10 .   ? -46.815 5.484   -47.747 0.98 45.10 ? 973  HOH H O   1 
HETATM 5844 O O   . HOH Q 10 .   ? -43.945 23.353  -44.906 1.00 51.51 ? 974  HOH H O   1 
HETATM 5845 O O   . HOH Q 10 .   ? -24.152 -0.515  -49.053 1.00 42.41 ? 975  HOH H O   1 
HETATM 5846 O O   . HOH Q 10 .   ? -47.453 7.105   -45.582 0.79 41.88 ? 976  HOH H O   1 
HETATM 5847 O O   . HOH Q 10 .   ? -14.899 10.307  -42.310 1.00 38.66 ? 977  HOH H O   1 
HETATM 5848 O O   . HOH Q 10 .   ? -9.374  35.608  -51.669 0.92 45.10 ? 978  HOH H O   1 
HETATM 5849 O O   . HOH Q 10 .   ? -18.991 16.578  -20.574 0.94 51.34 ? 979  HOH H O   1 
HETATM 5850 O O   . HOH Q 10 .   ? -35.481 31.874  -49.863 0.79 33.00 ? 980  HOH H O   1 
HETATM 5851 O O   . HOH Q 10 .   ? -38.367 28.550  -37.888 0.86 27.83 ? 981  HOH H O   1 
HETATM 5852 O O   . HOH Q 10 .   ? -27.006 44.252  -32.609 1.00 45.05 ? 982  HOH H O   1 
HETATM 5853 O O   . HOH Q 10 .   ? -25.110 -0.962  -46.267 1.00 46.99 ? 983  HOH H O   1 
HETATM 5854 O O   . HOH Q 10 .   ? -38.606 32.672  -44.998 1.00 45.93 ? 984  HOH H O   1 
HETATM 5855 O O   . HOH Q 10 .   ? -40.972 32.933  -46.116 1.00 34.92 ? 985  HOH H O   1 
HETATM 5856 O O   . HOH Q 10 .   ? -17.724 6.867   -56.465 1.00 35.00 ? 986  HOH H O   1 
HETATM 5857 O O   . HOH Q 10 .   ? -18.384 8.206   -60.230 0.89 33.54 ? 987  HOH H O   1 
HETATM 5858 O O   . HOH Q 10 .   ? -19.644 43.995  -40.006 0.98 27.86 ? 988  HOH H O   1 
HETATM 5859 O O   . HOH Q 10 .   ? -21.284 43.920  -43.706 0.87 32.49 ? 989  HOH H O   1 
HETATM 5860 O O   . HOH Q 10 .   ? -14.584 21.793  -22.644 1.00 65.52 ? 990  HOH H O   1 
HETATM 5861 O O   . HOH Q 10 .   ? -20.594 34.976  -58.532 1.00 58.88 ? 991  HOH H O   1 
HETATM 5862 O O   . HOH Q 10 .   ? -46.536 26.331  -45.903 0.82 27.68 ? 992  HOH H O   1 
HETATM 5863 O O   . HOH Q 10 .   ? -48.383 32.389  -53.085 1.00 43.92 ? 993  HOH H O   1 
HETATM 5864 O O   . HOH Q 10 .   ? -36.293 6.661   -59.253 0.98 31.11 ? 994  HOH H O   1 
HETATM 5865 O O   . HOH Q 10 .   ? -44.009 -1.288  -42.033 0.94 50.92 ? 995  HOH H O   1 
HETATM 5866 O O   . HOH Q 10 .   ? -40.545 -0.640  -40.735 0.94 30.13 ? 996  HOH H O   1 
HETATM 5867 O O   . HOH Q 10 .   ? -35.908 0.290   -36.043 1.00 16.69 ? 997  HOH H O   1 
HETATM 5868 O O   . HOH Q 10 .   ? -37.387 25.721  -64.873 0.89 25.77 ? 998  HOH H O   1 
HETATM 5869 O O   . HOH Q 10 .   ? -17.774 43.276  -41.868 0.95 27.85 ? 999  HOH H O   1 
HETATM 5870 O O   . HOH Q 10 .   ? -15.982 13.655  -18.127 0.97 43.23 ? 1000 HOH H O   1 
HETATM 5871 O O   . HOH Q 10 .   ? -21.245 15.575  -68.957 1.00 49.58 ? 1001 HOH H O   1 
HETATM 5872 O O   . HOH Q 10 .   ? -25.291 7.051   -58.211 1.00 51.39 ? 1002 HOH H O   1 
HETATM 5873 O O   . HOH Q 10 .   ? -13.224 15.670  -28.156 1.00 43.60 ? 1003 HOH H O   1 
HETATM 5874 O O   . HOH Q 10 .   ? -13.479 12.901  -26.719 0.96 45.26 ? 1004 HOH H O   1 
HETATM 5875 O O   . HOH Q 10 .   ? -13.351 32.123  -29.649 1.00 48.93 ? 1005 HOH H O   1 
HETATM 5876 O O   . HOH Q 10 .   ? -9.273  32.918  -41.022 0.90 38.48 ? 1006 HOH H O   1 
HETATM 5877 O O   . HOH Q 10 .   ? -7.684  34.934  -39.978 1.00 62.12 ? 1007 HOH H O   1 
HETATM 5878 O O   . HOH Q 10 .   ? -38.259 38.317  -41.126 0.96 37.58 ? 1008 HOH H O   1 
HETATM 5879 O O   . HOH Q 10 .   ? -22.130 43.298  -32.576 1.00 47.68 ? 1009 HOH H O   1 
HETATM 5880 O O   . HOH Q 10 .   ? -23.635 10.369  -63.291 1.00 44.71 ? 1010 HOH H O   1 
HETATM 5881 O O   . HOH Q 10 .   ? -26.584 10.348  -23.410 0.98 41.80 ? 1011 HOH H O   1 
HETATM 5882 O O   . HOH Q 10 .   ? -16.173 17.273  -18.872 1.00 54.06 ? 1012 HOH H O   1 
HETATM 5883 O O   . HOH Q 10 .   ? -13.979 23.194  -25.571 0.90 47.66 ? 1013 HOH H O   1 
HETATM 5884 O O   . HOH Q 10 .   ? -15.065 28.714  -21.221 1.00 62.35 ? 1014 HOH H O   1 
HETATM 5885 O O   . HOH Q 10 .   ? -5.129  18.659  -48.608 1.00 56.47 ? 1015 HOH H O   1 
HETATM 5886 O O   . HOH Q 10 .   ? -8.512  18.244  -57.529 0.83 35.70 ? 1016 HOH H O   1 
HETATM 5887 O O   . HOH Q 10 .   ? -7.969  20.734  -59.417 1.00 63.99 ? 1017 HOH H O   1 
HETATM 5888 O O   . HOH Q 10 .   ? -11.678 33.543  -41.603 0.98 64.45 ? 1018 HOH H O   1 
HETATM 5889 O O   . HOH Q 10 .   ? -11.326 32.704  -46.397 1.00 47.21 ? 1019 HOH H O   1 
HETATM 5890 O O   . HOH Q 10 .   ? -37.682 19.242  -26.657 1.00 50.45 ? 1020 HOH H O   1 
HETATM 5891 O O   . HOH Q 10 .   ? -39.851 17.876  -27.051 1.00 57.55 ? 1021 HOH H O   1 
HETATM 5892 O O   . HOH Q 10 .   ? -29.808 19.750  -19.624 1.00 57.47 ? 1022 HOH H O   1 
HETATM 5893 O O   . HOH Q 10 .   ? -28.127 13.372  -16.479 1.00 54.50 ? 1023 HOH H O   1 
HETATM 5894 O O   . HOH Q 10 .   ? -32.180 7.799   -27.345 0.97 50.28 ? 1024 HOH H O   1 
HETATM 5895 O O   . HOH Q 10 .   ? -10.750 35.137  -46.851 0.83 49.56 ? 1025 HOH H O   1 
HETATM 5896 O O   . HOH Q 10 .   ? -31.556 -2.729  -53.877 0.93 33.23 ? 1026 HOH H O   1 
HETATM 5897 O O   . HOH Q 10 .   ? -30.257 -0.679  -56.599 0.99 53.78 ? 1027 HOH H O   1 
HETATM 5898 O O   . HOH Q 10 .   ? -28.841 2.995   -57.608 0.92 41.45 ? 1028 HOH H O   1 
HETATM 5899 O O   . HOH Q 10 .   ? -31.986 7.507   -61.992 1.00 64.69 ? 1029 HOH H O   1 
HETATM 5900 O O   . HOH Q 10 .   ? -29.061 6.664   -60.736 1.00 52.24 ? 1030 HOH H O   1 
HETATM 5901 O O   . HOH Q 10 .   ? -39.723 30.928  -56.252 1.00 27.42 ? 1031 HOH H O   1 
HETATM 5902 O O   . HOH Q 10 .   ? -34.770 37.649  -35.732 0.90 40.43 ? 1032 HOH H O   1 
HETATM 5903 O O   . HOH Q 10 .   ? -16.150 43.699  -38.052 1.00 50.86 ? 1033 HOH H O   1 
HETATM 5904 O O   . HOH Q 10 .   ? -42.548 10.871  -57.008 1.00 57.40 ? 1034 HOH H O   1 
HETATM 5905 O O   . HOH Q 10 .   ? -20.412 19.736  -22.890 0.93 48.65 ? 1035 HOH H O   1 
HETATM 5906 O O   . HOH Q 10 .   ? -2.627  14.442  -50.504 0.93 42.88 ? 1036 HOH H O   1 
HETATM 5907 O O   . HOH Q 10 .   ? -0.984  15.130  -48.600 0.87 32.56 ? 1037 HOH H O   1 
HETATM 5908 O O   . HOH Q 10 .   ? -3.216  12.375  -49.067 0.93 43.58 ? 1038 HOH H O   1 
HETATM 5909 O O   . HOH Q 10 .   ? -3.621  28.860  -59.986 1.00 58.38 ? 1039 HOH H O   1 
HETATM 5910 O O   . HOH Q 10 .   ? -35.048 13.959  -24.372 0.97 40.76 ? 1040 HOH H O   1 
HETATM 5911 O O   . HOH Q 10 .   ? -22.708 -3.339  -44.381 1.00 42.10 ? 1041 HOH H O   1 
HETATM 5912 O O   . HOH Q 10 .   ? -20.626 -2.025  -45.303 0.90 36.76 ? 1042 HOH H O   1 
HETATM 5913 O O   . HOH Q 10 .   ? -10.266 1.785   -49.046 1.00 52.26 ? 1043 HOH H O   1 
HETATM 5914 O O   . HOH Q 10 .   ? -12.165 4.213   -52.164 1.00 47.91 ? 1044 HOH H O   1 
HETATM 5915 O O   . HOH Q 10 .   ? -47.121 0.023   -41.238 0.89 50.98 ? 1045 HOH H O   1 
HETATM 5916 O O   . HOH Q 10 .   ? -30.627 32.868  -30.112 1.00 46.13 ? 1046 HOH H O   1 
HETATM 5917 O O   . HOH Q 10 .   ? -29.659 30.512  -29.911 1.00 41.90 ? 1047 HOH H O   1 
HETATM 5918 O O   . HOH Q 10 .   ? -19.687 36.792  -33.524 0.79 41.93 ? 1048 HOH H O   1 
HETATM 5919 O O   . HOH Q 10 .   ? -7.437  8.846   -37.627 1.00 45.46 ? 1049 HOH H O   1 
HETATM 5920 O O   . HOH Q 10 .   ? -13.777 20.448  -65.537 0.77 36.28 ? 1050 HOH H O   1 
HETATM 5921 O O   . HOH Q 10 .   ? -37.820 34.157  -53.441 1.00 20.90 ? 1051 HOH H O   1 
HETATM 5922 O O   . HOH Q 10 .   ? -29.394 28.856  -66.522 1.00 31.84 ? 1052 HOH H O   1 
HETATM 5923 O O   . HOH Q 10 .   ? -21.102 33.961  -60.803 1.00 41.41 ? 1053 HOH H O   1 
HETATM 5924 O O   . HOH Q 10 .   ? -20.022 33.606  -63.058 1.00 43.88 ? 1054 HOH H O   1 
HETATM 5925 O O   . HOH R 10 .   ? -25.470 6.421   -39.768 1.00 16.87 ? 392  HOH I O   1 
HETATM 5926 O O   . HOH R 10 .   ? -28.561 11.521  -43.145 1.00 17.00 ? 393  HOH I O   1 
HETATM 5927 O O   . HOH R 10 .   ? 1.083   -5.349  31.091  0.93 28.17 ? 394  HOH I O   1 
HETATM 5928 O O   . HOH R 10 .   ? -22.715 6.570   -40.084 0.97 22.61 ? 395  HOH I O   1 
HETATM 5929 O O   . HOH R 10 .   ? -18.150 11.097  -34.296 1.00 25.99 ? 396  HOH I O   1 
HETATM 5930 O O   . HOH R 10 .   ? 2.849   -11.761 25.009  0.98 27.83 ? 397  HOH I O   1 
HETATM 5931 O O   . HOH R 10 .   ? 12.954  -4.916  19.493  0.97 30.90 ? 398  HOH I O   1 
HETATM 5932 O O   . HOH R 10 .   ? 8.961   6.409   -16.510 1.00 33.12 ? 399  HOH I O   1 
HETATM 5933 O O   . HOH R 10 .   ? 6.649   7.126   17.986  0.94 26.94 ? 400  HOH I O   1 
HETATM 5934 O O   . HOH R 10 .   ? -10.122 -4.263  28.918  1.00 30.23 ? 401  HOH I O   1 
HETATM 5935 O O   . HOH R 10 .   ? -19.306 8.360   -34.315 1.00 28.70 ? 402  HOH I O   1 
HETATM 5936 O O   . HOH R 10 .   ? -10.905 -6.819  28.361  1.00 31.47 ? 403  HOH I O   1 
HETATM 5937 O O   . HOH R 10 .   ? -19.382 8.208   -36.956 1.00 30.04 ? 404  HOH I O   1 
HETATM 5938 O O   . HOH R 10 .   ? 12.508  -12.272 22.361  0.97 32.12 ? 405  HOH I O   1 
HETATM 5939 O O   . HOH R 10 .   ? 6.654   1.411   27.316  0.87 30.88 ? 406  HOH I O   1 
HETATM 5940 O O   . HOH R 10 .   ? 13.046  -12.966 17.261  1.00 46.15 ? 407  HOH I O   1 
HETATM 5941 O O   . HOH R 10 .   ? -5.442  0.990   24.727  0.97 33.23 ? 408  HOH I O   1 
HETATM 5942 O O   . HOH R 10 .   ? -5.855  -10.266 13.592  0.94 32.21 ? 409  HOH I O   1 
HETATM 5943 O O   . HOH R 10 .   ? 14.208  5.794   9.082   1.00 36.09 ? 410  HOH I O   1 
HETATM 5944 O O   . HOH R 10 .   ? 2.321   -15.094 4.896   1.00 36.78 ? 411  HOH I O   1 
HETATM 5945 O O   . HOH R 10 .   ? -13.147 -0.460  -16.649 1.00 32.38 ? 412  HOH I O   1 
HETATM 5946 O O   . HOH R 10 .   ? 12.286  3.408   -19.886 0.99 36.94 ? 413  HOH I O   1 
HETATM 5947 O O   . HOH R 10 .   ? -10.497 -1.235  25.635  1.00 29.13 ? 414  HOH I O   1 
HETATM 5948 O O   . HOH R 10 .   ? 17.005  -16.413 25.261  1.00 38.70 ? 415  HOH I O   1 
HETATM 5949 O O   . HOH R 10 .   ? 10.317  14.174  -21.761 0.86 41.50 ? 416  HOH I O   1 
HETATM 5950 O O   . HOH R 10 .   ? -13.291 12.972  -35.491 0.88 31.37 ? 417  HOH I O   1 
HETATM 5951 O O   . HOH R 10 .   ? -12.011 5.785   -17.918 0.86 30.40 ? 418  HOH I O   1 
HETATM 5952 O O   . HOH R 10 .   ? 9.500   -7.648  29.206  1.00 36.56 ? 419  HOH I O   1 
HETATM 5953 O O   . HOH R 10 .   ? 3.740   -9.558  -13.342 0.99 37.36 ? 420  HOH I O   1 
HETATM 5954 O O   . HOH R 10 .   ? -7.173  -8.871  10.822  1.00 34.22 ? 421  HOH I O   1 
HETATM 5955 O O   . HOH R 10 .   ? -25.118 3.282   -32.310 0.96 35.47 ? 422  HOH I O   1 
HETATM 5956 O O   . HOH R 10 .   ? 13.660  -9.721  23.470  0.94 34.51 ? 423  HOH I O   1 
HETATM 5957 O O   . HOH R 10 .   ? 1.172   -0.004  31.645  0.98 35.76 ? 424  HOH I O   1 
HETATM 5958 O O   . HOH R 10 .   ? 9.273   -4.884  -1.881  1.00 36.63 ? 425  HOH I O   1 
HETATM 5959 O O   . HOH R 10 .   ? -7.632  -6.129  -12.953 1.00 33.86 ? 426  HOH I O   1 
HETATM 5960 O O   . HOH R 10 .   ? 13.632  8.273   18.664  0.86 44.48 ? 427  HOH I O   1 
HETATM 5961 O O   . HOH R 10 .   ? 9.702   -2.006  -3.132  0.90 37.16 ? 428  HOH I O   1 
HETATM 5962 O O   . HOH R 10 .   ? -6.451  -8.068  20.165  1.00 35.23 ? 429  HOH I O   1 
HETATM 5963 O O   . HOH R 10 .   ? -11.056 -1.510  -18.533 0.93 41.29 ? 430  HOH I O   1 
HETATM 5964 O O   . HOH R 10 .   ? -12.385 -1.754  23.957  1.00 36.03 ? 431  HOH I O   1 
HETATM 5965 O O   . HOH R 10 .   ? -6.561  -10.724 20.525  1.00 38.52 ? 432  HOH I O   1 
HETATM 5966 O O   . HOH R 10 .   ? 12.079  0.733   -0.161  1.00 40.74 ? 433  HOH I O   1 
HETATM 5967 O O   . HOH R 10 .   ? 11.844  -1.965  3.851   1.00 31.89 ? 434  HOH I O   1 
HETATM 5968 O O   . HOH R 10 .   ? -11.642 11.580  -28.040 1.00 34.49 ? 435  HOH I O   1 
HETATM 5969 O O   . HOH R 10 .   ? 2.283   6.363   -25.627 1.00 35.24 ? 436  HOH I O   1 
HETATM 5970 O O   . HOH R 10 .   ? 6.391   -6.775  -7.731  0.93 38.39 ? 437  HOH I O   1 
HETATM 5971 O O   . HOH R 10 .   ? 12.650  13.470  -13.709 0.95 39.59 ? 438  HOH I O   1 
HETATM 5972 O O   . HOH R 10 .   ? -4.474  -5.949  31.840  0.99 41.75 ? 439  HOH I O   1 
HETATM 5973 O O   . HOH R 10 .   ? 12.596  8.945   -16.092 1.00 37.18 ? 440  HOH I O   1 
HETATM 5974 O O   . HOH R 10 .   ? 7.367   -10.490 2.104   1.00 41.32 ? 441  HOH I O   1 
HETATM 5975 O O   . HOH R 10 .   ? -8.029  11.017  -28.169 1.00 44.89 ? 442  HOH I O   1 
HETATM 5976 O O   . HOH R 10 .   ? 11.492  -3.258  1.154   0.97 37.79 ? 443  HOH I O   1 
HETATM 5977 O O   . HOH R 10 .   ? 11.946  2.766   -6.839  1.00 39.71 ? 444  HOH I O   1 
HETATM 5978 O O   . HOH R 10 .   ? 12.640  -1.388  16.507  1.00 39.43 ? 445  HOH I O   1 
HETATM 5979 O O   . HOH R 10 .   ? 11.719  -1.438  -1.567  1.00 43.09 ? 446  HOH I O   1 
HETATM 5980 O O   . HOH R 10 .   ? -5.795  -2.837  30.939  0.94 35.79 ? 447  HOH I O   1 
HETATM 5981 O O   . HOH R 10 .   ? -1.170  18.466  -1.241  0.97 40.63 ? 448  HOH I O   1 
HETATM 5982 O O   . HOH R 10 .   ? -13.281 3.782   -19.465 0.94 40.18 ? 449  HOH I O   1 
HETATM 5983 O O   . HOH R 10 .   ? 2.819   -8.102  34.222  0.88 55.60 ? 450  HOH I O   1 
HETATM 5984 O O   . HOH R 10 .   ? 1.588   -6.780  35.991  0.84 43.44 ? 451  HOH I O   1 
HETATM 5985 O O   . HOH R 10 .   ? -7.073  -14.136 14.013  0.98 39.65 ? 452  HOH I O   1 
HETATM 5986 O O   . HOH R 10 .   ? 5.546   -0.218  29.408  1.00 41.84 ? 453  HOH I O   1 
HETATM 5987 O O   . HOH R 10 .   ? -1.640  -6.232  -26.967 0.88 50.72 ? 454  HOH I O   1 
HETATM 5988 O O   . HOH R 10 .   ? 0.852   -6.255  -28.267 1.00 47.54 ? 455  HOH I O   1 
HETATM 5989 O O   . HOH R 10 .   ? 3.784   10.481  -21.080 0.92 36.92 ? 456  HOH I O   1 
HETATM 5990 O O   . HOH R 10 .   ? -11.856 9.522   -38.653 1.00 43.15 ? 457  HOH I O   1 
HETATM 5991 O O   . HOH R 10 .   ? 9.380   8.190   -18.308 0.82 31.55 ? 458  HOH I O   1 
HETATM 5992 O O   . HOH R 10 .   ? 5.078   -0.214  34.908  1.00 39.47 ? 459  HOH I O   1 
HETATM 5993 O O   . HOH R 10 .   ? -7.293  -5.488  -10.228 0.92 39.97 ? 460  HOH I O   1 
HETATM 5994 O O   . HOH R 10 .   ? 2.620   -16.195 27.008  0.96 39.35 ? 461  HOH I O   1 
HETATM 5995 O O   . HOH R 10 .   ? -7.991  15.976  -20.479 0.97 42.67 ? 462  HOH I O   1 
HETATM 5996 O O   . HOH R 10 .   ? -8.897  -7.681  26.793  0.93 39.24 ? 463  HOH I O   1 
HETATM 5997 O O   . HOH R 10 .   ? -7.550  -6.166  10.954  1.00 44.98 ? 464  HOH I O   1 
HETATM 5998 O O   . HOH R 10 .   ? 5.906   -1.929  -26.466 0.93 36.26 ? 465  HOH I O   1 
HETATM 5999 O O   . HOH R 10 .   ? 11.217  -9.930  24.854  0.84 37.25 ? 466  HOH I O   1 
HETATM 6000 O O   . HOH R 10 .   ? 9.325   0.822   26.341  0.72 30.74 ? 467  HOH I O   1 
HETATM 6001 O O   . HOH R 10 .   ? 6.979   -0.080  33.019  1.00 47.70 ? 468  HOH I O   1 
HETATM 6002 O O   . HOH R 10 .   ? -21.913 4.183   -39.137 0.99 41.20 ? 469  HOH I O   1 
HETATM 6003 O O   . HOH R 10 .   ? 14.307  -8.008  17.026  0.99 43.79 ? 470  HOH I O   1 
HETATM 6004 O O   . HOH R 10 .   ? -6.752  -11.238 9.075   0.96 41.28 ? 471  HOH I O   1 
HETATM 6005 O O   . HOH R 10 .   ? 3.105   1.590   32.633  1.00 40.43 ? 472  HOH I O   1 
HETATM 6006 O O   . HOH R 10 .   ? 12.576  7.573   -9.886  1.00 44.02 ? 473  HOH I O   1 
HETATM 6007 O O   . HOH R 10 .   ? 9.458   14.066  0.359   0.97 48.29 ? 474  HOH I O   1 
HETATM 6008 O O   . HOH R 10 .   ? 8.715   -8.621  -16.634 1.00 60.48 ? 475  HOH I O   1 
HETATM 6009 O O   . HOH R 10 .   ? -6.297  7.085   2.328   1.00 45.60 ? 476  HOH I O   1 
HETATM 6010 O O   . HOH R 10 .   ? -5.433  16.886  -21.030 0.85 38.77 ? 477  HOH I O   1 
HETATM 6011 O O   . HOH R 10 .   ? 11.876  7.905   -19.196 0.77 34.10 ? 478  HOH I O   1 
HETATM 6012 O O   . HOH R 10 .   ? -16.090 -4.647  16.174  0.89 37.33 ? 479  HOH I O   1 
HETATM 6013 O O   . HOH R 10 .   ? 7.793   2.283   -28.055 1.00 42.88 ? 480  HOH I O   1 
HETATM 6014 O O   . HOH R 10 .   ? 5.321   1.191   31.501  1.00 46.23 ? 481  HOH I O   1 
HETATM 6015 O O   . HOH R 10 .   ? 7.224   -12.652 -26.373 1.00 46.83 ? 482  HOH I O   1 
HETATM 6016 O O   . HOH R 10 .   ? 2.841   7.358   29.804  0.88 39.51 ? 483  HOH I O   1 
HETATM 6017 O O   . HOH R 10 .   ? -7.701  -10.962 6.097   0.84 40.86 ? 484  HOH I O   1 
HETATM 6018 O O   . HOH R 10 .   ? 4.670   5.603   -24.365 0.78 35.72 ? 485  HOH I O   1 
HETATM 6019 O O   . HOH R 10 .   ? 4.903   -9.485  34.739  0.85 35.55 ? 486  HOH I O   1 
HETATM 6020 O O   . HOH R 10 .   ? 14.544  -3.974  11.902  0.89 41.29 ? 487  HOH I O   1 
HETATM 6021 O O   . HOH R 10 .   ? 3.493   15.590  -1.188  0.88 46.25 ? 489  HOH I O   1 
HETATM 6022 O O   . HOH R 10 .   ? -4.075  0.384   26.919  0.88 43.30 ? 490  HOH I O   1 
HETATM 6023 O O   . HOH R 10 .   ? -4.785  -8.741  28.213  1.00 48.42 ? 491  HOH I O   1 
HETATM 6024 O O   . HOH R 10 .   ? -10.133 12.655  -29.914 1.00 46.60 ? 492  HOH I O   1 
HETATM 6025 O O   . HOH R 10 .   ? -11.782 13.701  -33.507 1.00 41.57 ? 493  HOH I O   1 
HETATM 6026 O O   . HOH R 10 .   ? -5.211  6.685   19.964  0.90 38.01 ? 494  HOH I O   1 
HETATM 6027 O O   . HOH R 10 .   ? 11.366  5.593   -15.721 0.88 45.13 ? 495  HOH I O   1 
HETATM 6028 O O   . HOH R 10 .   ? 12.382  5.257   -13.306 1.00 46.52 ? 496  HOH I O   1 
HETATM 6029 O O   . HOH R 10 .   ? -4.437  16.415  -24.055 1.00 54.85 ? 497  HOH I O   1 
HETATM 6030 O O   . HOH R 10 .   ? -1.978  4.187   25.457  1.00 58.98 ? 498  HOH I O   1 
HETATM 6031 O O   . HOH R 10 .   ? -13.688 5.037   18.475  1.00 46.39 ? 499  HOH I O   1 
HETATM 6032 O O   . HOH R 10 .   ? 9.310   13.361  15.143  1.00 46.49 ? 500  HOH I O   1 
HETATM 6033 O O   . HOH R 10 .   ? -7.244  13.363  -30.128 1.00 58.64 ? 501  HOH I O   1 
HETATM 6034 O O   . HOH R 10 .   ? 14.258  1.410   13.730  0.80 44.23 ? 502  HOH I O   1 
HETATM 6035 O O   . HOH R 10 .   ? -14.056 -7.858  16.898  1.00 47.73 ? 503  HOH I O   1 
HETATM 6036 O O   . HOH R 10 .   ? 10.157  11.506  1.993   1.00 43.88 ? 504  HOH I O   1 
HETATM 6037 O O   . HOH R 10 .   ? -14.841 -4.201  23.633  1.00 40.76 ? 505  HOH I O   1 
HETATM 6038 O O   . HOH R 10 .   ? -9.292  -11.864 12.644  1.00 60.76 ? 506  HOH I O   1 
HETATM 6039 O O   . HOH R 10 .   ? 5.408   -19.473 19.739  1.00 44.51 ? 507  HOH I O   1 
HETATM 6040 O O   . HOH R 10 .   ? 17.403  -17.546 21.003  1.00 52.98 ? 508  HOH I O   1 
HETATM 6041 O O   . HOH R 10 .   ? 15.536  -18.570 25.632  0.98 40.79 ? 509  HOH I O   1 
HETATM 6042 O O   . HOH R 10 .   ? 3.943   -18.561 3.900   1.00 44.58 ? 510  HOH I O   1 
HETATM 6043 O O   . HOH R 10 .   ? 10.398  -10.006 5.266   1.00 59.12 ? 511  HOH I O   1 
HETATM 6044 O O   . HOH R 10 .   ? 14.613  -6.596  12.894  1.00 43.99 ? 512  HOH I O   1 
HETATM 6045 O O   . HOH R 10 .   ? -9.898  -7.478  -13.335 0.98 59.43 ? 513  HOH I O   1 
HETATM 6046 O O   . HOH R 10 .   ? 17.869  -5.029  -23.086 1.00 47.70 ? 514  HOH I O   1 
HETATM 6047 O O   . HOH R 10 .   ? -17.541 2.711   -23.476 1.00 47.24 ? 515  HOH I O   1 
HETATM 6048 O O   . HOH R 10 .   ? 0.109   19.083  -11.758 1.00 48.56 ? 516  HOH I O   1 
HETATM 6049 O O   . HOH R 10 .   ? 3.544   8.906   -24.017 0.97 42.98 ? 517  HOH I O   1 
HETATM 6050 O O   . HOH R 10 .   ? 3.949   13.142  -21.620 1.00 44.92 ? 518  HOH I O   1 
HETATM 6051 O O   . HOH R 10 .   ? -15.713 3.501   -10.551 1.00 44.66 ? 519  HOH I O   1 
HETATM 6052 O O   . HOH R 10 .   ? 8.055   11.030  -23.755 1.00 45.32 ? 520  HOH I O   1 
HETATM 6053 O O   . HOH R 10 .   ? 2.203   19.154  -5.227  0.99 54.18 ? 521  HOH I O   1 
HETATM 6054 O O   . HOH R 10 .   ? 2.986   -10.972 -6.726  1.00 48.63 ? 522  HOH I O   1 
HETATM 6055 O O   . HOH R 10 .   ? 5.876   -9.525  -8.250  1.00 52.46 ? 523  HOH I O   1 
HETATM 6056 O O   . HOH R 10 .   ? 10.139  8.467   24.028  1.00 53.04 ? 524  HOH I O   1 
HETATM 6057 O O   . HOH R 10 .   ? 16.959  1.976   20.670  1.00 48.34 ? 525  HOH I O   1 
HETATM 6058 O O   . HOH R 10 .   ? 12.827  -2.818  23.688  1.00 48.86 ? 526  HOH I O   1 
HETATM 6059 O O   . HOH R 10 .   ? 14.705  -3.622  17.227  1.00 44.34 ? 527  HOH I O   1 
HETATM 6060 O O   . HOH R 10 .   ? -13.796 -5.520  -24.414 1.00 39.80 ? 528  HOH I O   1 
HETATM 6061 O O   . HOH R 10 .   ? 2.768   2.653   -35.047 0.98 35.86 ? 529  HOH I O   1 
HETATM 6062 O O   . HOH R 10 .   ? 8.384   4.430   -24.006 1.00 48.98 ? 530  HOH I O   1 
HETATM 6063 O O   . HOH R 10 .   ? -12.261 3.319   1.228   1.00 51.10 ? 531  HOH I O   1 
HETATM 6064 O O   . HOH R 10 .   ? 13.888  2.292   -14.114 0.91 44.48 ? 532  HOH I O   1 
HETATM 6065 O O   . HOH R 10 .   ? 5.795   -9.783  -16.914 1.00 54.33 ? 533  HOH I O   1 
HETATM 6066 O O   . HOH R 10 .   ? -4.561  -19.552 12.446  1.00 54.17 ? 534  HOH I O   1 
HETATM 6067 O O   . HOH R 10 .   ? -2.447  14.958  -25.227 1.00 46.16 ? 535  HOH I O   1 
HETATM 6068 O O   . HOH R 10 .   ? 8.384   17.870  -9.333  0.94 45.67 ? 536  HOH I O   1 
HETATM 6069 O O   . HOH R 10 .   ? 14.079  -3.431  4.812   1.00 54.87 ? 537  HOH I O   1 
HETATM 6070 O O   . HOH R 10 .   ? 13.455  4.907   15.514  0.73 39.87 ? 538  HOH I O   1 
HETATM 6071 O O   . HOH R 10 .   ? 3.374   -9.567  -15.935 0.99 49.08 ? 539  HOH I O   1 
HETATM 6072 O O   . HOH R 10 .   ? -30.378 6.224   -28.402 1.00 48.60 ? 540  HOH I O   1 
HETATM 6073 O O   . HOH R 10 .   ? 12.016  9.274   -4.048  0.95 49.81 ? 541  HOH I O   1 
HETATM 6074 O O   . HOH R 10 .   ? 7.288   12.357  26.332  1.00 46.43 ? 542  HOH I O   1 
HETATM 6075 O O   . HOH R 10 .   ? -9.409  12.864  21.563  1.00 56.99 ? 543  HOH I O   1 
HETATM 6076 O O   . HOH R 10 .   ? -2.263  20.467  -16.985 1.00 59.23 ? 545  HOH I O   1 
HETATM 6077 O O   . HOH R 10 .   ? 6.568   8.591   -25.145 0.99 48.45 ? 546  HOH I O   1 
HETATM 6078 O O   . HOH R 10 .   ? 13.317  15.829  -12.182 0.95 53.87 ? 547  HOH I O   1 
HETATM 6079 O O   . HOH R 10 .   ? 8.756   16.632  -3.057  0.90 45.20 ? 548  HOH I O   1 
HETATM 6080 O O   . HOH R 10 .   ? 9.873   -7.195  4.280   1.00 48.03 ? 549  HOH I O   1 
HETATM 6081 O O   . HOH R 10 .   ? 15.843  -1.560  12.704  0.98 42.15 ? 550  HOH I O   1 
HETATM 6082 O O   . HOH R 10 .   ? -17.533 6.159   -33.685 1.00 48.21 ? 551  HOH I O   1 
HETATM 6083 O O   . HOH R 10 .   ? 11.435  11.093  -5.715  0.92 55.13 ? 552  HOH I O   1 
HETATM 6084 O O   . HOH R 10 .   ? -14.623 5.220   7.491   1.00 53.51 ? 553  HOH I O   1 
HETATM 6085 O O   . HOH R 10 .   ? 16.258  -15.700 3.276   1.00 51.73 ? 554  HOH I O   1 
HETATM 6086 O O   . HOH R 10 .   ? 1.903   -13.422 -27.105 1.00 51.78 ? 555  HOH I O   1 
HETATM 6087 O O   . HOH R 10 .   ? -10.263 -2.612  -28.619 0.90 48.44 ? 556  HOH I O   1 
HETATM 6088 O O   . HOH R 10 .   ? 8.841   7.369   -25.741 1.00 60.50 ? 557  HOH I O   1 
HETATM 6089 O O   . HOH R 10 .   ? 14.387  -4.034  14.742  1.00 50.47 ? 558  HOH I O   1 
HETATM 6090 O O   . HOH R 10 .   ? 14.651  3.974   4.273   0.98 48.00 ? 559  HOH I O   1 
HETATM 6091 O O   . HOH R 10 .   ? 12.058  11.536  13.962  1.00 52.63 ? 560  HOH I O   1 
HETATM 6092 O O   . HOH R 10 .   ? 2.831   -12.843 -1.531  1.00 55.25 ? 561  HOH I O   1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   THR 1   -2  ?   ?   ?   L . n 
A 1 2   ALA 2   -1  ?   ?   ?   L . n 
A 1 3   THR 3   0   ?   ?   ?   L . n 
A 1 4   SER 4   1   1   SER SER L R n 
A 1 5   GLU 5   1   1   GLU GLU L Q n 
A 1 6   TYR 6   1   1   TYR TYR L P n 
A 1 7   GLN 7   1   1   GLN GLN L O n 
A 1 8   THR 8   1   1   THR THR L N n 
A 1 9   PHE 9   1   1   PHE PHE L M n 
A 1 10  PHE 10  1   1   PHE PHE L L n 
A 1 11  ASN 11  1   1   ASN ASN L K n 
A 1 12  PRO 12  1   1   PRO PRO L J n 
A 1 13  ARG 13  1   1   ARG ARG L I n 
A 1 14  THR 14  1   1   THR THR L H n 
A 1 15  PHE 15  1   1   PHE PHE L G n 
A 1 16  GLY 16  1   1   GLY GLY L F n 
A 1 17  SER 17  1   1   SER SER L E n 
A 1 18  GLY 18  1   1   GLY GLY L D n 
A 1 19  GLU 19  1   1   GLU GLU L C n 
A 1 20  ALA 20  1   1   ALA ALA L B n 
A 1 21  ASP 21  1   1   ASP ASP L A n 
A 1 22  CYS 22  1   1   CYS CYS L . n 
A 1 23  GLY 23  2   2   GLY GLY L . n 
A 1 24  LEU 24  3   3   LEU LEU L . n 
A 1 25  ARG 25  4   4   ARG ARG L . n 
A 1 26  PRO 26  5   5   PRO PRO L . n 
A 1 27  LEU 27  6   6   LEU LEU L . n 
A 1 28  PHE 28  7   7   PHE PHE L . n 
A 1 29  GLU 29  8   8   GLU GLU L . n 
A 1 30  LYS 30  9   9   LYS LYS L . n 
A 1 31  LYS 31  10  10  LYS LYS L . n 
A 1 32  SER 32  11  11  SER SER L . n 
A 1 33  LEU 33  12  12  LEU LEU L . n 
A 1 34  GLU 34  13  13  GLU GLU L . n 
A 1 35  ASP 35  14  14  ASP ASP L . n 
A 1 36  LYS 36  14  14  LYS LYS L A n 
A 1 37  THR 37  14  14  THR THR L B n 
A 1 38  GLU 38  14  14  GLU GLU L C n 
A 1 39  ARG 39  14  14  ARG ARG L D n 
A 1 40  GLU 40  14  14  GLU GLU L E n 
A 1 41  LEU 41  14  14  LEU LEU L F n 
A 1 42  LEU 42  14  14  LEU LEU L G n 
A 1 43  GLU 43  14  14  GLU GLU L H n 
A 1 44  SER 44  14  14  SER SER L I n 
A 1 45  TYR 45  14  14  TYR TYR L J n 
A 1 46  ILE 46  14  14  ILE ILE L K n 
A 1 47  ASP 47  14  14  ASP ASP L L n 
A 1 48  GLY 48  15  ?   ?   ?   L . n 
A 1 49  ARG 49  16  ?   ?   ?   L . n 
B 2 1   ILE 1   16  16  ILE ILE H . n 
B 2 2   VAL 2   17  17  VAL VAL H . n 
B 2 3   GLU 3   18  18  GLU GLU H . n 
B 2 4   GLY 4   19  19  GLY GLY H . n 
B 2 5   SER 5   20  20  SER SER H . n 
B 2 6   ASP 6   21  21  ASP ASP H . n 
B 2 7   ALA 7   22  22  ALA ALA H . n 
B 2 8   GLU 8   23  23  GLU GLU H . n 
B 2 9   ILE 9   24  24  ILE ILE H . n 
B 2 10  GLY 10  25  25  GLY GLY H . n 
B 2 11  MET 11  26  26  MET MET H . n 
B 2 12  SER 12  27  27  SER SER H . n 
B 2 13  PRO 13  28  28  PRO PRO H . n 
B 2 14  TRP 14  29  29  TRP TRP H . n 
B 2 15  GLN 15  30  30  GLN GLN H . n 
B 2 16  VAL 16  31  31  VAL VAL H . n 
B 2 17  MET 17  32  32  MET MET H . n 
B 2 18  LEU 18  33  33  LEU LEU H . n 
B 2 19  PHE 19  34  34  PHE PHE H . n 
B 2 20  ARG 20  35  35  ARG ARG H . n 
B 2 21  LYS 21  36  36  LYS LYS H . n 
B 2 22  SER 22  36  36  SER SER H A n 
B 2 23  PRO 23  37  37  PRO PRO H . n 
B 2 24  GLN 24  38  38  GLN GLN H . n 
B 2 25  GLU 25  39  39  GLU GLU H . n 
B 2 26  LEU 26  40  40  LEU LEU H . n 
B 2 27  LEU 27  41  41  LEU LEU H . n 
B 2 28  CYS 28  42  42  CYS CYS H . n 
B 2 29  GLY 29  43  43  GLY GLY H . n 
B 2 30  ALA 30  44  44  ALA ALA H . n 
B 2 31  SER 31  45  45  SER SER H . n 
B 2 32  LEU 32  46  46  LEU LEU H . n 
B 2 33  ILE 33  47  47  ILE ILE H . n 
B 2 34  SER 34  48  48  SER SER H . n 
B 2 35  ASP 35  49  49  ASP ASP H . n 
B 2 36  ARG 36  50  50  ARG ARG H . n 
B 2 37  TRP 37  51  51  TRP TRP H . n 
B 2 38  VAL 38  52  52  VAL VAL H . n 
B 2 39  LEU 39  53  53  LEU LEU H . n 
B 2 40  THR 40  54  54  THR THR H . n 
B 2 41  ALA 41  55  55  ALA ALA H . n 
B 2 42  ALA 42  56  56  ALA ALA H . n 
B 2 43  HIS 43  57  57  HIS HIS H . n 
B 2 44  CYS 44  58  58  CYS CYS H . n 
B 2 45  LEU 45  59  59  LEU LEU H . n 
B 2 46  LEU 46  60  60  LEU LEU H . n 
B 2 47  TYR 47  60  60  TYR TYR H A n 
B 2 48  PRO 48  60  60  PRO PRO H B n 
B 2 49  PRO 49  60  60  PRO PRO H C n 
B 2 50  TRP 50  60  60  TRP TRP H D n 
B 2 51  ASP 51  60  60  ASP ASP H E n 
B 2 52  LYS 52  60  60  LYS LYS H F n 
B 2 53  ASN 53  60  60  ASN ASN H G n 
B 2 54  PHE 54  60  60  PHE PHE H H n 
B 2 55  THR 55  60  60  THR THR H I n 
B 2 56  GLU 56  61  61  GLU GLU H . n 
B 2 57  ASN 57  62  62  ASN ASN H . n 
B 2 58  ASP 58  63  63  ASP ASP H . n 
B 2 59  LEU 59  64  64  LEU LEU H . n 
B 2 60  LEU 60  65  65  LEU LEU H . n 
B 2 61  VAL 61  66  66  VAL VAL H . n 
B 2 62  ARG 62  67  67  ARG ARG H . n 
B 2 63  ILE 63  68  68  ILE ILE H . n 
B 2 64  GLY 64  69  69  GLY GLY H . n 
B 2 65  LYS 65  70  70  LYS LYS H . n 
B 2 66  HIS 66  71  71  HIS HIS H . n 
B 2 67  SER 67  72  72  SER SER H . n 
B 2 68  ARG 68  73  73  ARG ARG H . n 
B 2 69  THR 69  74  74  THR THR H . n 
B 2 70  ARG 70  75  75  ARG ARG H . n 
B 2 71  TYR 71  76  76  TYR TYR H . n 
B 2 72  GLU 72  77  77  GLU GLU H . n 
B 2 73  ARG 73  77  77  ARG ARG H A n 
B 2 74  ASN 74  78  78  ASN ASN H . n 
B 2 75  ILE 75  79  79  ILE ILE H . n 
B 2 76  GLU 76  80  80  GLU GLU H . n 
B 2 77  LYS 77  81  81  LYS LYS H . n 
B 2 78  ILE 78  82  82  ILE ILE H . n 
B 2 79  SER 79  83  83  SER SER H . n 
B 2 80  MET 80  84  84  MET MET H . n 
B 2 81  LEU 81  85  85  LEU LEU H . n 
B 2 82  GLU 82  86  86  GLU GLU H . n 
B 2 83  LYS 83  87  87  LYS LYS H . n 
B 2 84  ILE 84  88  88  ILE ILE H . n 
B 2 85  TYR 85  89  89  TYR TYR H . n 
B 2 86  ILE 86  90  90  ILE ILE H . n 
B 2 87  HIS 87  91  91  HIS HIS H . n 
B 2 88  PRO 88  92  92  PRO PRO H . n 
B 2 89  ARG 89  93  93  ARG ARG H . n 
B 2 90  TYR 90  94  94  TYR TYR H . n 
B 2 91  ASN 91  95  95  ASN ASN H . n 
B 2 92  TRP 92  96  96  TRP TRP H . n 
B 2 93  ARG 93  97  97  ARG ARG H . n 
B 2 94  GLU 94  97  97  GLU GLU H A n 
B 2 95  ASN 95  98  98  ASN ASN H . n 
B 2 96  LEU 96  99  99  LEU LEU H . n 
B 2 97  ASP 97  100 100 ASP ASP H . n 
B 2 98  ARG 98  101 101 ARG ARG H . n 
B 2 99  ASP 99  102 102 ASP ASP H . n 
B 2 100 ILE 100 103 103 ILE ILE H . n 
B 2 101 ALA 101 104 104 ALA ALA H . n 
B 2 102 LEU 102 105 105 LEU LEU H . n 
B 2 103 MET 103 106 106 MET MET H . n 
B 2 104 LYS 104 107 107 LYS LYS H . n 
B 2 105 LEU 105 108 108 LEU LEU H . n 
B 2 106 LYS 106 109 109 LYS LYS H . n 
B 2 107 LYS 107 110 110 LYS LYS H . n 
B 2 108 PRO 108 111 111 PRO PRO H . n 
B 2 109 VAL 109 112 112 VAL VAL H . n 
B 2 110 ALA 110 113 113 ALA ALA H . n 
B 2 111 PHE 111 114 114 PHE PHE H . n 
B 2 112 SER 112 115 115 SER SER H . n 
B 2 113 ASP 113 116 116 ASP ASP H . n 
B 2 114 TYR 114 117 117 TYR TYR H . n 
B 2 115 ILE 115 118 118 ILE ILE H . n 
B 2 116 HIS 116 119 119 HIS HIS H . n 
B 2 117 PRO 117 120 120 PRO PRO H . n 
B 2 118 VAL 118 121 121 VAL VAL H . n 
B 2 119 CYS 119 122 122 CYS CYS H . n 
B 2 120 LEU 120 123 123 LEU LEU H . n 
B 2 121 PRO 121 124 124 PRO PRO H . n 
B 2 122 ASP 122 125 125 ASP ASP H . n 
B 2 123 ARG 123 126 126 ARG ARG H . n 
B 2 124 GLU 124 127 127 GLU GLU H . n 
B 2 125 THR 125 128 128 THR THR H . n 
B 2 126 ALA 126 129 129 ALA ALA H . n 
B 2 127 ALA 127 129 129 ALA ALA H A n 
B 2 128 SER 128 129 129 SER SER H B n 
B 2 129 LEU 129 129 129 LEU LEU H C n 
B 2 130 LEU 130 130 130 LEU LEU H . n 
B 2 131 GLN 131 131 131 GLN GLN H . n 
B 2 132 ALA 132 132 132 ALA ALA H . n 
B 2 133 GLY 133 133 133 GLY GLY H . n 
B 2 134 TYR 134 134 134 TYR TYR H . n 
B 2 135 LYS 135 135 135 LYS LYS H . n 
B 2 136 GLY 136 136 136 GLY GLY H . n 
B 2 137 ARG 137 137 137 ARG ARG H . n 
B 2 138 VAL 138 138 138 VAL VAL H . n 
B 2 139 THR 139 139 139 THR THR H . n 
B 2 140 GLY 140 140 140 GLY GLY H . n 
B 2 141 TRP 141 141 141 TRP TRP H . n 
B 2 142 GLY 142 142 142 GLY GLY H . n 
B 2 143 ASN 143 143 143 ASN ASN H . n 
B 2 144 LEU 144 144 144 LEU LEU H . n 
B 2 145 LYS 145 145 145 LYS LYS H . n 
B 2 146 GLU 146 146 146 GLU GLU H . n 
B 2 147 THR 147 147 147 THR THR H . n 
B 2 148 TRP 148 147 ?   ?   ?   H A n 
B 2 149 THR 149 147 ?   ?   ?   H B n 
B 2 150 ALA 150 147 ?   ?   ?   H C n 
B 2 151 ASN 151 147 ?   ?   ?   H D n 
B 2 152 VAL 152 147 ?   ?   ?   H E n 
B 2 153 GLY 153 147 ?   ?   ?   H F n 
B 2 154 LYS 154 149 149 LYS LYS H . n 
B 2 155 GLY 155 150 150 GLY GLY H . n 
B 2 156 GLN 156 151 151 GLN GLN H . n 
B 2 157 PRO 157 152 152 PRO PRO H . n 
B 2 158 SER 158 153 153 SER SER H . n 
B 2 159 VAL 159 154 154 VAL VAL H . n 
B 2 160 LEU 160 155 155 LEU LEU H . n 
B 2 161 GLN 161 156 156 GLN GLN H . n 
B 2 162 VAL 162 157 157 VAL VAL H . n 
B 2 163 VAL 163 158 158 VAL VAL H . n 
B 2 164 ASN 164 159 159 ASN ASN H . n 
B 2 165 LEU 165 160 160 LEU LEU H . n 
B 2 166 PRO 166 161 161 PRO PRO H . n 
B 2 167 ILE 167 162 162 ILE ILE H . n 
B 2 168 VAL 168 163 163 VAL VAL H . n 
B 2 169 GLU 169 164 164 GLU GLU H . n 
B 2 170 ARG 170 165 165 ARG ARG H . n 
B 2 171 PRO 171 166 166 PRO PRO H . n 
B 2 172 VAL 172 167 167 VAL VAL H . n 
B 2 173 CYS 173 168 168 CYS CYS H . n 
B 2 174 LYS 174 169 169 LYS LYS H . n 
B 2 175 ASP 175 170 170 ASP ASP H . n 
B 2 176 SER 176 171 171 SER SER H . n 
B 2 177 THR 177 172 172 THR THR H . n 
B 2 178 ARG 178 173 173 ARG ARG H . n 
B 2 179 ILE 179 174 174 ILE ILE H . n 
B 2 180 ARG 180 175 175 ARG ARG H . n 
B 2 181 ILE 181 176 176 ILE ILE H . n 
B 2 182 THR 182 177 177 THR THR H . n 
B 2 183 ASP 183 178 178 ASP ASP H . n 
B 2 184 ASN 184 179 179 ASN ASN H . n 
B 2 185 MET 185 180 180 MET MET H . n 
B 2 186 PHE 186 181 181 PHE PHE H . n 
B 2 187 CYS 187 182 182 CYS CYS H . n 
B 2 188 ALA 188 183 183 ALA ALA H . n 
B 2 189 GLY 189 184 184 GLY GLY H . n 
B 2 190 TYR 190 184 184 TYR TYR H A n 
B 2 191 LYS 191 185 185 LYS LYS H . n 
B 2 192 PRO 192 186 186 PRO PRO H . n 
B 2 193 ASP 193 186 186 ASP ASP H A n 
B 2 194 GLU 194 186 186 GLU GLU H B n 
B 2 195 GLY 195 186 186 GLY GLY H C n 
B 2 196 LYS 196 186 186 LYS LYS H D n 
B 2 197 ARG 197 187 187 ARG ARG H . n 
B 2 198 GLY 198 188 188 GLY GLY H . n 
B 2 199 ASP 199 189 189 ASP ASP H . n 
B 2 200 ALA 200 190 190 ALA ALA H . n 
B 2 201 CYS 201 191 191 CYS CYS H . n 
B 2 202 GLU 202 192 192 GLU GLU H . n 
B 2 203 GLY 203 193 193 GLY GLY H . n 
B 2 204 ASP 204 194 194 ASP ASP H . n 
B 2 205 ALA 205 195 195 ALA ALA H . n 
B 2 206 GLY 206 196 196 GLY GLY H . n 
B 2 207 GLY 207 197 197 GLY GLY H . n 
B 2 208 PRO 208 198 198 PRO PRO H . n 
B 2 209 PHE 209 199 199 PHE PHE H . n 
B 2 210 VAL 210 200 200 VAL VAL H . n 
B 2 211 MET 211 201 201 MET MET H . n 
B 2 212 LYS 212 202 202 LYS LYS H . n 
B 2 213 SER 213 203 203 SER SER H . n 
B 2 214 PRO 214 204 204 PRO PRO H . n 
B 2 215 PHE 215 204 204 PHE PHE H A n 
B 2 216 ASN 216 204 204 ASN ASN H B n 
B 2 217 ASN 217 205 205 ASN ASN H . n 
B 2 218 ARG 218 206 206 ARG ARG H . n 
B 2 219 TRP 219 207 207 TRP TRP H . n 
B 2 220 TYR 220 208 208 TYR TYR H . n 
B 2 221 GLN 221 209 209 GLN GLN H . n 
B 2 222 MET 222 210 210 MET MET H . n 
B 2 223 GLY 223 211 211 GLY GLY H . n 
B 2 224 ILE 224 212 212 ILE ILE H . n 
B 2 225 VAL 225 213 213 VAL VAL H . n 
B 2 226 SER 226 214 214 SER SER H . n 
B 2 227 TRP 227 215 215 TRP TRP H . n 
B 2 228 GLY 228 216 216 GLY GLY H . n 
B 2 229 GLU 229 217 217 GLU GLU H . n 
B 2 230 GLY 230 219 219 GLY GLY H . n 
B 2 231 CYS 231 220 220 CYS CYS H . n 
B 2 232 ASP 232 221 221 ASP ASP H . n 
B 2 233 ARG 233 221 221 ARG ARG H A n 
B 2 234 ASP 234 222 222 ASP ASP H . n 
B 2 235 GLY 235 223 223 GLY GLY H . n 
B 2 236 LYS 236 224 224 LYS LYS H . n 
B 2 237 TYR 237 225 225 TYR TYR H . n 
B 2 238 GLY 238 226 226 GLY GLY H . n 
B 2 239 PHE 239 227 227 PHE PHE H . n 
B 2 240 TYR 240 228 228 TYR TYR H . n 
B 2 241 THR 241 229 229 THR THR H . n 
B 2 242 HIS 242 230 230 HIS HIS H . n 
B 2 243 VAL 243 231 231 VAL VAL H . n 
B 2 244 PHE 244 232 232 PHE PHE H . n 
B 2 245 ARG 245 233 233 ARG ARG H . n 
B 2 246 LEU 246 234 234 LEU LEU H . n 
B 2 247 LYS 247 235 235 LYS LYS H . n 
B 2 248 LYS 248 236 236 LYS LYS H . n 
B 2 249 TRP 249 237 237 TRP TRP H . n 
B 2 250 ILE 250 238 238 ILE ILE H . n 
B 2 251 GLN 251 239 239 GLN GLN H . n 
B 2 252 LYS 252 240 240 LYS LYS H . n 
B 2 253 VAL 253 241 241 VAL VAL H . n 
B 2 254 ILE 254 242 242 ILE ILE H . n 
B 2 255 ASP 255 243 243 ASP ASP H . n 
B 2 256 GLN 256 244 244 GLN GLN H . n 
B 2 257 PHE 257 245 245 PHE PHE H . n 
B 2 258 GLY 258 246 246 GLY GLY H . n 
B 2 259 GLU 259 247 247 GLU GLU H . n 
C 3 1   MET 1   -7  ?   ?   ?   I . n 
C 3 2   GLY 2   -6  ?   ?   ?   I . n 
C 3 3   HIS 3   -5  ?   ?   ?   I . n 
C 3 4   HIS 4   -4  ?   ?   ?   I . n 
C 3 5   HIS 5   -3  ?   ?   ?   I . n 
C 3 6   HIS 6   -2  ?   ?   ?   I . n 
C 3 7   HIS 7   -1  ?   ?   ?   I . n 
C 3 8   HIS 8   0   ?   ?   ?   I . n 
C 3 9   HIS 9   1   ?   ?   ?   I . n 
C 3 10  HIS 10  2   ?   ?   ?   I . n 
C 3 11  HIS 11  3   ?   ?   ?   I . n 
C 3 12  HIS 12  4   ?   ?   ?   I . n 
C 3 13  SER 13  5   ?   ?   ?   I . n 
C 3 14  SER 14  6   ?   ?   ?   I . n 
C 3 15  GLY 15  7   ?   ?   ?   I . n 
C 3 16  HIS 16  8   ?   ?   ?   I . n 
C 3 17  ILE 17  9   ?   ?   ?   I . n 
C 3 18  ASP 18  10  ?   ?   ?   I . n 
C 3 19  ASP 19  11  ?   ?   ?   I . n 
C 3 20  ASP 20  12  ?   ?   ?   I . n 
C 3 21  ASP 21  13  ?   ?   ?   I . n 
C 3 22  LYS 22  14  ?   ?   ?   I . n 
C 3 23  HIS 23  15  ?   ?   ?   I . n 
C 3 24  MET 24  16  ?   ?   ?   I . n 
C 3 25  VAL 25  17  ?   ?   ?   I . n 
C 3 26  GLY 26  18  ?   ?   ?   I . n 
C 3 27  ALA 27  19  ?   ?   ?   I . n 
C 3 28  THR 28  20  ?   ?   ?   I . n 
C 3 29  VAL 29  21  ?   ?   ?   I . n 
C 3 30  ALA 30  22  ?   ?   ?   I . n 
C 3 31  PRO 31  23  ?   ?   ?   I . n 
C 3 32  SER 32  24  ?   ?   ?   I . n 
C 3 33  SER 33  25  ?   ?   ?   I . n 
C 3 34  ARG 34  26  ?   ?   ?   I . n 
C 3 35  ARG 35  27  ?   ?   ?   I . n 
C 3 36  ASP 36  28  28  ASP ASP I . n 
C 3 37  PHE 37  29  29  PHE PHE I . n 
C 3 38  THR 38  30  30  THR THR I . n 
C 3 39  PHE 39  31  31  PHE PHE I . n 
C 3 40  ASP 40  32  32  ASP ASP I . n 
C 3 41  LEU 41  33  33  LEU LEU I . n 
C 3 42  TYR 42  34  34  TYR TYR I . n 
C 3 43  ARG 43  35  35  ARG ARG I . n 
C 3 44  ALA 44  36  36  ALA ALA I . n 
C 3 45  LEU 45  37  37  LEU LEU I . n 
C 3 46  ALA 46  38  38  ALA ALA I . n 
C 3 47  SER 47  39  39  SER SER I . n 
C 3 48  ALA 48  40  40  ALA ALA I . n 
C 3 49  ALA 49  41  41  ALA ALA I . n 
C 3 50  PRO 50  42  42  PRO PRO I . n 
C 3 51  SER 51  43  43  SER SER I . n 
C 3 52  GLN 52  44  44  GLN GLN I . n 
C 3 53  ASN 53  45  45  ASN ASN I . n 
C 3 54  ILE 54  46  46  ILE ILE I . n 
C 3 55  PHE 55  47  47  PHE PHE I . n 
C 3 56  PHE 56  48  48  PHE PHE I . n 
C 3 57  SER 57  49  49  SER SER I . n 
C 3 58  PRO 58  50  50  PRO PRO I . n 
C 3 59  VAL 59  51  51  VAL VAL I . n 
C 3 60  SER 60  52  52  SER SER I . n 
C 3 61  ILE 61  53  53  ILE ILE I . n 
C 3 62  SER 62  54  54  SER SER I . n 
C 3 63  MET 63  55  55  MET MET I . n 
C 3 64  SER 64  56  56  SER SER I . n 
C 3 65  LEU 65  57  57  LEU LEU I . n 
C 3 66  ALA 66  58  58  ALA ALA I . n 
C 3 67  MET 67  59  59  MET MET I . n 
C 3 68  LEU 68  60  60  LEU LEU I . n 
C 3 69  SER 69  61  61  SER SER I . n 
C 3 70  LEU 70  62  62  LEU LEU I . n 
C 3 71  GLY 71  63  63  GLY GLY I . n 
C 3 72  ALA 72  64  64  ALA ALA I . n 
C 3 73  GLY 73  65  65  GLY GLY I . n 
C 3 74  SER 74  66  66  SER SER I . n 
C 3 75  SER 75  67  67  SER SER I . n 
C 3 76  THR 76  68  68  THR THR I . n 
C 3 77  LYS 77  69  69  LYS LYS I . n 
C 3 78  MET 78  70  70  MET MET I . n 
C 3 79  GLN 79  71  71  GLN GLN I . n 
C 3 80  ILE 80  72  72  ILE ILE I . n 
C 3 81  LEU 81  73  73  LEU LEU I . n 
C 3 82  GLU 82  74  74  GLU GLU I . n 
C 3 83  GLY 83  75  75  GLY GLY I . n 
C 3 84  LEU 84  76  76  LEU LEU I . n 
C 3 85  GLY 85  77  77  GLY GLY I . n 
C 3 86  LEU 86  78  78  LEU LEU I . n 
C 3 87  ASN 87  79  ?   ?   ?   I . n 
C 3 88  LEU 88  80  ?   ?   ?   I . n 
C 3 89  GLN 89  81  ?   ?   ?   I . n 
C 3 90  LYS 90  82  ?   ?   ?   I . n 
C 3 91  SER 91  83  83  SER SER I . n 
C 3 92  SER 92  84  84  SER SER I . n 
C 3 93  GLU 93  85  85  GLU GLU I . n 
C 3 94  LYS 94  86  86  LYS LYS I . n 
C 3 95  GLU 95  87  87  GLU GLU I . n 
C 3 96  LEU 96  88  88  LEU LEU I . n 
C 3 97  HIS 97  89  89  HIS HIS I . n 
C 3 98  ARG 98  90  90  ARG ARG I . n 
C 3 99  GLY 99  91  91  GLY GLY I . n 
C 3 100 PHE 100 92  92  PHE PHE I . n 
C 3 101 GLN 101 93  93  GLN GLN I . n 
C 3 102 GLN 102 94  94  GLN GLN I . n 
C 3 103 LEU 103 95  95  LEU LEU I . n 
C 3 104 LEU 104 96  96  LEU LEU I . n 
C 3 105 GLN 105 97  97  GLN GLN I . n 
C 3 106 GLU 106 98  98  GLU GLU I . n 
C 3 107 LEU 107 99  99  LEU LEU I . n 
C 3 108 ASN 108 100 100 ASN ASN I . n 
C 3 109 GLN 109 101 101 GLN GLN I . n 
C 3 110 PRO 110 102 102 PRO PRO I . n 
C 3 111 ARG 111 103 103 ARG ARG I . n 
C 3 112 ASP 112 104 104 ASP ASP I . n 
C 3 113 GLY 113 105 105 GLY GLY I . n 
C 3 114 PHE 114 106 106 PHE PHE I . n 
C 3 115 GLN 115 107 107 GLN GLN I . n 
C 3 116 LEU 116 108 108 LEU LEU I . n 
C 3 117 SER 117 109 109 SER SER I . n 
C 3 118 LEU 118 110 110 LEU LEU I . n 
C 3 119 GLY 119 111 111 GLY GLY I . n 
C 3 120 ASN 120 112 112 ASN ASN I . n 
C 3 121 ALA 121 113 113 ALA ALA I . n 
C 3 122 LEU 122 114 114 LEU LEU I . n 
C 3 123 PHE 123 115 115 PHE PHE I . n 
C 3 124 THR 124 116 116 THR THR I . n 
C 3 125 ASP 125 117 117 ASP ASP I . n 
C 3 126 LEU 126 118 118 LEU LEU I . n 
C 3 127 VAL 127 119 119 VAL VAL I . n 
C 3 128 VAL 128 120 120 VAL VAL I . n 
C 3 129 ASP 129 121 121 ASP ASP I . n 
C 3 130 LEU 130 122 122 LEU LEU I . n 
C 3 131 GLN 131 123 123 GLN GLN I . n 
C 3 132 ASP 132 124 124 ASP ASP I . n 
C 3 133 THR 133 125 125 THR THR I . n 
C 3 134 PHE 134 126 126 PHE PHE I . n 
C 3 135 VAL 135 127 127 VAL VAL I . n 
C 3 136 SER 136 128 128 SER SER I . n 
C 3 137 ALA 137 129 129 ALA ALA I . n 
C 3 138 MET 138 130 130 MET MET I . n 
C 3 139 LYS 139 131 131 LYS LYS I . n 
C 3 140 THR 140 132 132 THR THR I . n 
C 3 141 LEU 141 133 133 LEU LEU I . n 
C 3 142 TYR 142 134 134 TYR TYR I . n 
C 3 143 LEU 143 135 135 LEU LEU I . n 
C 3 144 ALA 144 136 136 ALA ALA I . n 
C 3 145 ASP 145 137 137 ASP ASP I . n 
C 3 146 THR 146 138 138 THR THR I . n 
C 3 147 PHE 147 139 139 PHE PHE I . n 
C 3 148 PRO 148 140 140 PRO PRO I . n 
C 3 149 THR 149 141 141 THR THR I . n 
C 3 150 ASN 150 142 142 ASN ASN I . n 
C 3 151 PHE 151 143 143 PHE PHE I . n 
C 3 152 ARG 152 144 144 ARG ARG I . n 
C 3 153 ASP 153 145 145 ASP ASP I . n 
C 3 154 SER 154 146 146 SER SER I . n 
C 3 155 ALA 155 147 147 ALA ALA I . n 
C 3 156 GLY 156 148 148 GLY GLY I . n 
C 3 157 ALA 157 149 149 ALA ALA I . n 
C 3 158 MET 158 150 150 MET MET I . n 
C 3 159 LYS 159 151 151 LYS LYS I . n 
C 3 160 GLN 160 152 152 GLN GLN I . n 
C 3 161 ILE 161 153 153 ILE ILE I . n 
C 3 162 ASN 162 154 154 ASN ASN I . n 
C 3 163 ASP 163 155 155 ASP ASP I . n 
C 3 164 TYR 164 156 156 TYR TYR I . n 
C 3 165 VAL 165 157 157 VAL VAL I . n 
C 3 166 ALA 166 158 158 ALA ALA I . n 
C 3 167 LYS 167 159 159 LYS LYS I . n 
C 3 168 GLN 168 160 160 GLN GLN I . n 
C 3 169 THR 169 161 161 THR THR I . n 
C 3 170 LYS 170 162 162 LYS LYS I . n 
C 3 171 GLY 171 163 163 GLY GLY I . n 
C 3 172 LYS 172 164 164 LYS LYS I . n 
C 3 173 ILE 173 165 165 ILE ILE I . n 
C 3 174 VAL 174 166 166 VAL VAL I . n 
C 3 175 ASP 175 167 167 ASP ASP I . n 
C 3 176 LEU 176 168 168 LEU LEU I . n 
C 3 177 LEU 177 169 169 LEU LEU I . n 
C 3 178 LYS 178 170 170 LYS LYS I . n 
C 3 179 ASN 179 171 171 ASN ASN I . n 
C 3 180 LEU 180 172 172 LEU LEU I . n 
C 3 181 ASP 181 173 173 ASP ASP I . n 
C 3 182 SER 182 174 174 SER SER I . n 
C 3 183 ASN 183 175 175 ASN ASN I . n 
C 3 184 ALA 184 176 176 ALA ALA I . n 
C 3 185 VAL 185 177 177 VAL VAL I . n 
C 3 186 VAL 186 178 178 VAL VAL I . n 
C 3 187 ILE 187 179 179 ILE ILE I . n 
C 3 188 MET 188 180 180 MET MET I . n 
C 3 189 VAL 189 181 181 VAL VAL I . n 
C 3 190 ASN 190 182 182 ASN ASN I . n 
C 3 191 TYR 191 183 183 TYR TYR I . n 
C 3 192 ILE 192 184 184 ILE ILE I . n 
C 3 193 PHE 193 185 185 PHE PHE I . n 
C 3 194 PHE 194 186 186 PHE PHE I . n 
C 3 195 LYS 195 187 187 LYS LYS I . n 
C 3 196 ALA 196 188 188 ALA ALA I . n 
C 3 197 LYS 197 189 189 LYS LYS I . n 
C 3 198 TRP 198 190 190 TRP TRP I . n 
C 3 199 GLU 199 191 191 GLU GLU I . n 
C 3 200 THR 200 192 192 THR THR I . n 
C 3 201 SER 201 193 193 SER SER I . n 
C 3 202 PHE 202 194 194 PHE PHE I . n 
C 3 203 ASN 203 195 195 ASN ASN I . n 
C 3 204 HIS 204 196 196 HIS HIS I . n 
C 3 205 LYS 205 197 197 LYS LYS I . n 
C 3 206 GLY 206 198 198 GLY GLY I . n 
C 3 207 THR 207 199 199 THR THR I . n 
C 3 208 GLN 208 200 200 GLN GLN I . n 
C 3 209 GLU 209 201 201 GLU GLU I . n 
C 3 210 GLN 210 202 202 GLN GLN I . n 
C 3 211 ASP 211 203 203 ASP ASP I . n 
C 3 212 PHE 212 204 204 PHE PHE I . n 
C 3 213 TYR 213 205 205 TYR TYR I . n 
C 3 214 VAL 214 206 206 VAL VAL I . n 
C 3 215 THR 215 207 207 THR THR I . n 
C 3 216 SER 216 208 208 SER SER I . n 
C 3 217 GLU 217 209 209 GLU GLU I . n 
C 3 218 THR 218 210 210 THR THR I . n 
C 3 219 VAL 219 211 211 VAL VAL I . n 
C 3 220 VAL 220 212 212 VAL VAL I . n 
C 3 221 ARG 221 213 213 ARG ARG I . n 
C 3 222 VAL 222 214 214 VAL VAL I . n 
C 3 223 PRO 223 215 215 PRO PRO I . n 
C 3 224 MET 224 216 216 MET MET I . n 
C 3 225 MET 225 217 217 MET MET I . n 
C 3 226 SER 226 218 218 SER SER I . n 
C 3 227 ARG 227 219 219 ARG ARG I . n 
C 3 228 GLU 228 220 220 GLU GLU I . n 
C 3 229 ASP 229 221 221 ASP ASP I . n 
C 3 230 GLN 230 222 222 GLN GLN I . n 
C 3 231 TYR 231 223 223 TYR TYR I . n 
C 3 232 HIS 232 224 224 HIS HIS I . n 
C 3 233 TYR 233 225 225 TYR TYR I . n 
C 3 234 LEU 234 226 226 LEU LEU I . n 
C 3 235 LEU 235 227 227 LEU LEU I . n 
C 3 236 ASP 236 228 228 ASP ASP I . n 
C 3 237 ARG 237 229 229 ARG ARG I . n 
C 3 238 ASN 238 230 230 ASN ASN I . n 
C 3 239 LEU 239 231 231 LEU LEU I . n 
C 3 240 SER 240 232 232 SER SER I . n 
C 3 241 CYS 241 233 233 CYS CYS I . n 
C 3 242 ARG 242 234 234 ARG ARG I . n 
C 3 243 VAL 243 235 235 VAL VAL I . n 
C 3 244 VAL 244 236 236 VAL VAL I . n 
C 3 245 GLY 245 237 237 GLY GLY I . n 
C 3 246 VAL 246 238 238 VAL VAL I . n 
C 3 247 PRO 247 239 239 PRO PRO I . n 
C 3 248 TYR 248 240 240 TYR TYR I . n 
C 3 249 GLN 249 241 241 GLN GLN I . n 
C 3 250 GLY 250 242 242 GLY GLY I . n 
C 3 251 ASN 251 243 243 ASN ASN I . n 
C 3 252 ALA 252 244 244 ALA ALA I . n 
C 3 253 THR 253 245 245 THR THR I . n 
C 3 254 ALA 254 246 246 ALA ALA I . n 
C 3 255 LEU 255 247 247 LEU LEU I . n 
C 3 256 PHE 256 248 248 PHE PHE I . n 
C 3 257 ILE 257 249 249 ILE ILE I . n 
C 3 258 LEU 258 250 250 LEU LEU I . n 
C 3 259 PRO 259 251 251 PRO PRO I . n 
C 3 260 SER 260 252 252 SER SER I . n 
C 3 261 GLU 261 253 253 GLU GLU I . n 
C 3 262 GLY 262 254 254 GLY GLY I . n 
C 3 263 LYS 263 255 255 LYS LYS I . n 
C 3 264 MET 264 256 256 MET MET I . n 
C 3 265 GLN 265 257 257 GLN GLN I . n 
C 3 266 GLN 266 258 258 GLN GLN I . n 
C 3 267 VAL 267 259 259 VAL VAL I . n 
C 3 268 GLU 268 260 260 GLU GLU I . n 
C 3 269 ASN 269 261 261 ASN ASN I . n 
C 3 270 GLY 270 262 262 GLY GLY I . n 
C 3 271 LEU 271 263 263 LEU LEU I . n 
C 3 272 SER 272 264 264 SER SER I . n 
C 3 273 GLU 273 265 265 GLU GLU I . n 
C 3 274 LYS 274 266 266 LYS LYS I . n 
C 3 275 THR 275 267 267 THR THR I . n 
C 3 276 LEU 276 268 268 LEU LEU I . n 
C 3 277 ARG 277 269 269 ARG ARG I . n 
C 3 278 LYS 278 270 270 LYS LYS I . n 
C 3 279 TRP 279 271 271 TRP TRP I . n 
C 3 280 LEU 280 272 272 LEU LEU I . n 
C 3 281 LYS 281 273 273 LYS LYS I . n 
C 3 282 MET 282 274 274 MET MET I . n 
C 3 283 PHE 283 275 275 PHE PHE I . n 
C 3 284 LYS 284 276 276 LYS LYS I . n 
C 3 285 LYS 285 277 277 LYS LYS I . n 
C 3 286 ARG 286 278 278 ARG ARG I . n 
C 3 287 GLN 287 279 279 GLN GLN I . n 
C 3 288 LEU 288 280 280 LEU LEU I . n 
C 3 289 GLU 289 281 281 GLU GLU I . n 
C 3 290 LEU 290 282 282 LEU LEU I . n 
C 3 291 TYR 291 283 283 TYR TYR I . n 
C 3 292 LEU 292 284 284 LEU LEU I . n 
C 3 293 PRO 293 285 285 PRO PRO I . n 
C 3 294 LYS 294 286 286 LYS LYS I . n 
C 3 295 PHE 295 287 287 PHE PHE I . n 
C 3 296 SER 296 288 288 SER SER I . n 
C 3 297 ILE 297 289 289 ILE ILE I . n 
C 3 298 GLU 298 290 290 GLU GLU I . n 
C 3 299 GLY 299 291 291 GLY GLY I . n 
C 3 300 SER 300 292 292 SER SER I . n 
C 3 301 TYR 301 293 293 TYR TYR I . n 
C 3 302 GLN 302 294 294 GLN GLN I . n 
C 3 303 LEU 303 295 295 LEU LEU I . n 
C 3 304 GLU 304 296 296 GLU GLU I . n 
C 3 305 LYS 305 297 297 LYS LYS I . n 
C 3 306 VAL 306 298 298 VAL VAL I . n 
C 3 307 LEU 307 299 299 LEU LEU I . n 
C 3 308 PRO 308 300 300 PRO PRO I . n 
C 3 309 SER 309 301 301 SER SER I . n 
C 3 310 LEU 310 302 302 LEU LEU I . n 
C 3 311 GLY 311 303 303 GLY GLY I . n 
C 3 312 ILE 312 304 304 ILE ILE I . n 
C 3 313 SER 313 305 305 SER SER I . n 
C 3 314 ASN 314 306 306 ASN ASN I . n 
C 3 315 VAL 315 307 307 VAL VAL I . n 
C 3 316 PHE 316 308 308 PHE PHE I . n 
C 3 317 THR 317 309 309 THR THR I . n 
C 3 318 SER 318 310 310 SER SER I . n 
C 3 319 HIS 319 311 311 HIS HIS I . n 
C 3 320 ALA 320 312 312 ALA ALA I . n 
C 3 321 ASP 321 313 313 ASP ASP I . n 
C 3 322 LEU 322 314 314 LEU LEU I . n 
C 3 323 SER 323 315 315 SER SER I . n 
C 3 324 GLY 324 316 316 GLY GLY I . n 
C 3 325 ILE 325 317 317 ILE ILE I . n 
C 3 326 SER 326 318 318 SER SER I . n 
C 3 327 ASN 327 319 319 ASN ASN I . n 
C 3 328 HIS 328 320 320 HIS HIS I . n 
C 3 329 SER 329 321 321 SER SER I . n 
C 3 330 ASN 330 322 322 ASN ASN I . n 
C 3 331 ILE 331 323 323 ILE ILE I . n 
C 3 332 GLN 332 324 324 GLN GLN I . n 
C 3 333 VAL 333 325 325 VAL VAL I . n 
C 3 334 SER 334 326 326 SER SER I . n 
C 3 335 GLU 335 327 327 GLU GLU I . n 
C 3 336 MET 336 328 328 MET MET I . n 
C 3 337 VAL 337 329 329 VAL VAL I . n 
C 3 338 HIS 338 330 330 HIS HIS I . n 
C 3 339 LYS 339 331 331 LYS LYS I . n 
C 3 340 ALA 340 332 332 ALA ALA I . n 
C 3 341 VAL 341 333 333 VAL VAL I . n 
C 3 342 VAL 342 334 334 VAL VAL I . n 
C 3 343 GLU 343 335 335 GLU GLU I . n 
C 3 344 VAL 344 336 336 VAL VAL I . n 
C 3 345 ASP 345 337 337 ASP ASP I . n 
C 3 346 GLU 346 338 338 GLU GLU I . n 
C 3 347 SER 347 339 339 SER SER I . n 
C 3 348 GLY 348 340 340 GLY GLY I . n 
C 3 349 THR 349 341 341 THR THR I . n 
C 3 350 ARG 350 342 342 ARG ARG I . n 
C 3 351 ALA 351 343 343 ALA ALA I . n 
C 3 352 ALA 352 344 344 ALA ALA I . n 
C 3 353 ALA 353 345 345 ALA ALA I . n 
C 3 354 ALA 354 346 346 ALA ALA I . n 
C 3 355 THR 355 347 347 THR ALA I . n 
C 3 356 GLY 356 348 348 GLY GLY I . n 
C 3 357 THR 357 349 349 THR THR I . n 
C 3 358 ILE 358 350 350 ILE ILE I . n 
C 3 359 PHE 359 351 351 PHE PHE I . n 
C 3 360 THR 360 352 352 THR THR I . n 
C 3 361 PHE 361 353 353 PHE PHE I . n 
C 3 362 ARG 362 354 354 ARG ARG I . n 
C 3 363 SER 363 355 355 SER SER I . n 
C 3 364 ALA 364 356 356 ALA ALA I . n 
C 3 365 ARG 365 357 357 ARG ARG I . n 
C 3 366 LEU 366 358 358 LEU LEU I . n 
C 3 367 ASN 367 359 359 ASN ASN I . n 
C 3 368 SER 368 360 360 SER SER I . n 
C 3 369 GLN 369 361 361 GLN GLN I . n 
C 3 370 ARG 370 362 362 ARG ARG I . n 
C 3 371 LEU 371 363 363 LEU LEU I . n 
C 3 372 VAL 372 364 364 VAL VAL I . n 
C 3 373 PHE 373 365 365 PHE PHE I . n 
C 3 374 ASN 374 366 366 ASN ASN I . n 
C 3 375 ARG 375 367 367 ARG ARG I . n 
C 3 376 PRO 376 368 368 PRO PRO I . n 
C 3 377 PHE 377 369 369 PHE PHE I . n 
C 3 378 LEU 378 370 370 LEU LEU I . n 
C 3 379 MET 379 371 371 MET MET I . n 
C 3 380 PHE 380 372 372 PHE PHE I . n 
C 3 381 ILE 381 373 373 ILE ILE I . n 
C 3 382 VAL 382 374 374 VAL VAL I . n 
C 3 383 ASP 383 375 375 ASP ASP I . n 
C 3 384 ASN 384 376 376 ASN ASN I . n 
C 3 385 ASN 385 377 377 ASN ASN I . n 
C 3 386 ILE 386 378 378 ILE ILE I . n 
C 3 387 LEU 387 379 379 LEU LEU I . n 
C 3 388 PHE 388 380 380 PHE PHE I . n 
C 3 389 LEU 389 381 381 LEU LEU I . n 
C 3 390 GLY 390 382 382 GLY GLY I . n 
C 3 391 LYS 391 383 383 LYS LYS I . n 
C 3 392 VAL 392 384 384 VAL VAL I . n 
C 3 393 ASN 393 385 385 ASN ASN I . n 
C 3 394 ARG 394 386 386 ARG ARG I . n 
C 3 395 PRO 395 387 387 PRO PRO I . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4  NAG 1   778  778 NAG NAG H . 
E 5  FUC 2   780  780 FUC FUC H . 
F 6  SGN 1   1    1   SGN SGN H . 
G 7  IDS 2   2    2   IDS IDS H . 
H 8  SO4 1   781  1   SO4 SO4 H . 
I 9  GOL 1   782  1   GOL GOL H . 
J 9  GOL 1   3    3   GOL GOL H . 
K 9  GOL 1   4    4   GOL GOL H . 
L 8  SO4 1   388  2   SO4 SO4 I . 
M 8  SO4 1   389  3   SO4 SO4 I . 
N 9  GOL 1   390  2   GOL GOL I . 
O 9  GOL 1   391  5   GOL GOL I . 
P 10 HOH 1   17   4   HOH HOH L . 
P 10 HOH 2   18   16  HOH HOH L . 
P 10 HOH 3   19   24  HOH HOH L . 
P 10 HOH 4   20   31  HOH HOH L . 
P 10 HOH 5   21   35  HOH HOH L . 
P 10 HOH 6   22   36  HOH HOH L . 
P 10 HOH 7   24   42  HOH HOH L . 
P 10 HOH 8   25   45  HOH HOH L . 
P 10 HOH 9   26   48  HOH HOH L . 
P 10 HOH 10  27   49  HOH HOH L . 
P 10 HOH 11  28   57  HOH HOH L . 
P 10 HOH 12  29   62  HOH HOH L . 
P 10 HOH 13  30   63  HOH HOH L . 
P 10 HOH 14  31   65  HOH HOH L . 
P 10 HOH 15  32   73  HOH HOH L . 
P 10 HOH 16  33   80  HOH HOH L . 
P 10 HOH 17  34   91  HOH HOH L . 
P 10 HOH 18  35   97  HOH HOH L . 
P 10 HOH 19  36   102 HOH HOH L . 
P 10 HOH 20  37   113 HOH HOH L . 
P 10 HOH 21  38   120 HOH HOH L . 
P 10 HOH 22  39   121 HOH HOH L . 
P 10 HOH 23  40   125 HOH HOH L . 
P 10 HOH 24  41   135 HOH HOH L . 
P 10 HOH 25  42   137 HOH HOH L . 
P 10 HOH 26  43   141 HOH HOH L . 
P 10 HOH 27  44   144 HOH HOH L . 
P 10 HOH 28  46   151 HOH HOH L . 
P 10 HOH 29  47   152 HOH HOH L . 
P 10 HOH 30  48   156 HOH HOH L . 
P 10 HOH 31  49   163 HOH HOH L . 
P 10 HOH 32  50   165 HOH HOH L . 
P 10 HOH 33  51   171 HOH HOH L . 
P 10 HOH 34  52   182 HOH HOH L . 
P 10 HOH 35  53   188 HOH HOH L . 
P 10 HOH 36  54   192 HOH HOH L . 
P 10 HOH 37  55   195 HOH HOH L . 
P 10 HOH 38  56   204 HOH HOH L . 
P 10 HOH 39  57   216 HOH HOH L . 
P 10 HOH 40  58   219 HOH HOH L . 
P 10 HOH 41  59   224 HOH HOH L . 
P 10 HOH 42  60   229 HOH HOH L . 
P 10 HOH 43  61   233 HOH HOH L . 
P 10 HOH 44  62   241 HOH HOH L . 
P 10 HOH 45  63   244 HOH HOH L . 
P 10 HOH 46  64   253 HOH HOH L . 
P 10 HOH 47  65   269 HOH HOH L . 
P 10 HOH 48  66   274 HOH HOH L . 
P 10 HOH 49  67   276 HOH HOH L . 
P 10 HOH 50  68   279 HOH HOH L . 
P 10 HOH 51  69   280 HOH HOH L . 
P 10 HOH 52  70   302 HOH HOH L . 
P 10 HOH 53  71   313 HOH HOH L . 
P 10 HOH 54  72   316 HOH HOH L . 
P 10 HOH 55  73   318 HOH HOH L . 
P 10 HOH 56  74   328 HOH HOH L . 
P 10 HOH 57  75   334 HOH HOH L . 
P 10 HOH 58  76   345 HOH HOH L . 
P 10 HOH 59  77   347 HOH HOH L . 
P 10 HOH 60  78   371 HOH HOH L . 
P 10 HOH 61  79   372 HOH HOH L . 
P 10 HOH 62  80   377 HOH HOH L . 
P 10 HOH 63  81   378 HOH HOH L . 
P 10 HOH 64  82   379 HOH HOH L . 
P 10 HOH 65  83   380 HOH HOH L . 
P 10 HOH 66  84   383 HOH HOH L . 
P 10 HOH 67  85   384 HOH HOH L . 
P 10 HOH 68  86   385 HOH HOH L . 
P 10 HOH 69  87   389 HOH HOH L . 
P 10 HOH 70  89   433 HOH HOH L . 
P 10 HOH 71  91   435 HOH HOH L . 
P 10 HOH 72  92   436 HOH HOH L . 
P 10 HOH 73  93   437 HOH HOH L . 
P 10 HOH 74  94   438 HOH HOH L . 
P 10 HOH 75  95   454 HOH HOH L . 
P 10 HOH 76  96   455 HOH HOH L . 
P 10 HOH 77  97   456 HOH HOH L . 
P 10 HOH 78  98   458 HOH HOH L . 
P 10 HOH 79  99   459 HOH HOH L . 
P 10 HOH 80  100  495 HOH HOH L . 
P 10 HOH 81  101  496 HOH HOH L . 
P 10 HOH 82  102  497 HOH HOH L . 
P 10 HOH 83  488  329 HOH HOH L . 
Q 10 HOH 1   783  1   HOH HOH H . 
Q 10 HOH 2   784  2   HOH HOH H . 
Q 10 HOH 3   785  3   HOH HOH H . 
Q 10 HOH 4   786  5   HOH HOH H . 
Q 10 HOH 5   787  6   HOH HOH H . 
Q 10 HOH 6   788  7   HOH HOH H . 
Q 10 HOH 7   789  8   HOH HOH H . 
Q 10 HOH 8   790  9   HOH HOH H . 
Q 10 HOH 9   791  10  HOH HOH H . 
Q 10 HOH 10  792  11  HOH HOH H . 
Q 10 HOH 11  793  12  HOH HOH H . 
Q 10 HOH 12  794  13  HOH HOH H . 
Q 10 HOH 13  795  15  HOH HOH H . 
Q 10 HOH 14  796  17  HOH HOH H . 
Q 10 HOH 15  797  18  HOH HOH H . 
Q 10 HOH 16  798  20  HOH HOH H . 
Q 10 HOH 17  799  21  HOH HOH H . 
Q 10 HOH 18  800  22  HOH HOH H . 
Q 10 HOH 19  801  23  HOH HOH H . 
Q 10 HOH 20  802  25  HOH HOH H . 
Q 10 HOH 21  803  26  HOH HOH H . 
Q 10 HOH 22  804  27  HOH HOH H . 
Q 10 HOH 23  805  28  HOH HOH H . 
Q 10 HOH 24  806  29  HOH HOH H . 
Q 10 HOH 25  807  30  HOH HOH H . 
Q 10 HOH 26  808  32  HOH HOH H . 
Q 10 HOH 27  809  33  HOH HOH H . 
Q 10 HOH 28  810  34  HOH HOH H . 
Q 10 HOH 29  811  37  HOH HOH H . 
Q 10 HOH 30  812  39  HOH HOH H . 
Q 10 HOH 31  813  40  HOH HOH H . 
Q 10 HOH 32  814  41  HOH HOH H . 
Q 10 HOH 33  815  43  HOH HOH H . 
Q 10 HOH 34  816  44  HOH HOH H . 
Q 10 HOH 35  817  46  HOH HOH H . 
Q 10 HOH 36  818  47  HOH HOH H . 
Q 10 HOH 37  819  50  HOH HOH H . 
Q 10 HOH 38  820  51  HOH HOH H . 
Q 10 HOH 39  821  52  HOH HOH H . 
Q 10 HOH 40  822  53  HOH HOH H . 
Q 10 HOH 41  823  54  HOH HOH H . 
Q 10 HOH 42  824  56  HOH HOH H . 
Q 10 HOH 43  825  58  HOH HOH H . 
Q 10 HOH 44  826  59  HOH HOH H . 
Q 10 HOH 45  827  60  HOH HOH H . 
Q 10 HOH 46  828  66  HOH HOH H . 
Q 10 HOH 47  829  67  HOH HOH H . 
Q 10 HOH 48  830  69  HOH HOH H . 
Q 10 HOH 49  831  70  HOH HOH H . 
Q 10 HOH 50  832  71  HOH HOH H . 
Q 10 HOH 51  833  72  HOH HOH H . 
Q 10 HOH 52  834  74  HOH HOH H . 
Q 10 HOH 53  835  75  HOH HOH H . 
Q 10 HOH 54  836  76  HOH HOH H . 
Q 10 HOH 55  837  77  HOH HOH H . 
Q 10 HOH 56  838  78  HOH HOH H . 
Q 10 HOH 57  839  79  HOH HOH H . 
Q 10 HOH 58  840  83  HOH HOH H . 
Q 10 HOH 59  841  84  HOH HOH H . 
Q 10 HOH 60  842  85  HOH HOH H . 
Q 10 HOH 61  843  87  HOH HOH H . 
Q 10 HOH 62  844  88  HOH HOH H . 
Q 10 HOH 63  845  89  HOH HOH H . 
Q 10 HOH 64  846  90  HOH HOH H . 
Q 10 HOH 65  847  93  HOH HOH H . 
Q 10 HOH 66  848  94  HOH HOH H . 
Q 10 HOH 67  849  95  HOH HOH H . 
Q 10 HOH 68  850  96  HOH HOH H . 
Q 10 HOH 69  851  99  HOH HOH H . 
Q 10 HOH 70  852  101 HOH HOH H . 
Q 10 HOH 71  853  103 HOH HOH H . 
Q 10 HOH 72  854  104 HOH HOH H . 
Q 10 HOH 73  855  105 HOH HOH H . 
Q 10 HOH 74  856  106 HOH HOH H . 
Q 10 HOH 75  857  107 HOH HOH H . 
Q 10 HOH 76  858  109 HOH HOH H . 
Q 10 HOH 77  859  110 HOH HOH H . 
Q 10 HOH 78  860  111 HOH HOH H . 
Q 10 HOH 79  861  112 HOH HOH H . 
Q 10 HOH 80  862  115 HOH HOH H . 
Q 10 HOH 81  863  117 HOH HOH H . 
Q 10 HOH 82  864  118 HOH HOH H . 
Q 10 HOH 83  865  119 HOH HOH H . 
Q 10 HOH 84  866  123 HOH HOH H . 
Q 10 HOH 85  867  124 HOH HOH H . 
Q 10 HOH 86  868  126 HOH HOH H . 
Q 10 HOH 87  869  127 HOH HOH H . 
Q 10 HOH 88  870  128 HOH HOH H . 
Q 10 HOH 89  871  131 HOH HOH H . 
Q 10 HOH 90  872  133 HOH HOH H . 
Q 10 HOH 91  873  136 HOH HOH H . 
Q 10 HOH 92  874  139 HOH HOH H . 
Q 10 HOH 93  875  140 HOH HOH H . 
Q 10 HOH 94  876  142 HOH HOH H . 
Q 10 HOH 95  877  143 HOH HOH H . 
Q 10 HOH 96  878  145 HOH HOH H . 
Q 10 HOH 97  879  153 HOH HOH H . 
Q 10 HOH 98  880  155 HOH HOH H . 
Q 10 HOH 99  881  158 HOH HOH H . 
Q 10 HOH 100 882  159 HOH HOH H . 
Q 10 HOH 101 883  160 HOH HOH H . 
Q 10 HOH 102 884  161 HOH HOH H . 
Q 10 HOH 103 885  162 HOH HOH H . 
Q 10 HOH 104 886  164 HOH HOH H . 
Q 10 HOH 105 887  169 HOH HOH H . 
Q 10 HOH 106 888  172 HOH HOH H . 
Q 10 HOH 107 889  176 HOH HOH H . 
Q 10 HOH 108 890  178 HOH HOH H . 
Q 10 HOH 109 891  181 HOH HOH H . 
Q 10 HOH 110 892  185 HOH HOH H . 
Q 10 HOH 111 893  186 HOH HOH H . 
Q 10 HOH 112 894  187 HOH HOH H . 
Q 10 HOH 113 895  189 HOH HOH H . 
Q 10 HOH 114 896  191 HOH HOH H . 
Q 10 HOH 115 897  199 HOH HOH H . 
Q 10 HOH 116 898  200 HOH HOH H . 
Q 10 HOH 117 899  201 HOH HOH H . 
Q 10 HOH 118 900  202 HOH HOH H . 
Q 10 HOH 119 901  206 HOH HOH H . 
Q 10 HOH 120 902  207 HOH HOH H . 
Q 10 HOH 121 903  208 HOH HOH H . 
Q 10 HOH 122 904  209 HOH HOH H . 
Q 10 HOH 123 905  212 HOH HOH H . 
Q 10 HOH 124 906  213 HOH HOH H . 
Q 10 HOH 125 907  214 HOH HOH H . 
Q 10 HOH 126 908  215 HOH HOH H . 
Q 10 HOH 127 909  218 HOH HOH H . 
Q 10 HOH 128 910  223 HOH HOH H . 
Q 10 HOH 129 911  225 HOH HOH H . 
Q 10 HOH 130 912  226 HOH HOH H . 
Q 10 HOH 131 913  230 HOH HOH H . 
Q 10 HOH 132 914  232 HOH HOH H . 
Q 10 HOH 133 915  234 HOH HOH H . 
Q 10 HOH 134 916  235 HOH HOH H . 
Q 10 HOH 135 917  237 HOH HOH H . 
Q 10 HOH 136 918  239 HOH HOH H . 
Q 10 HOH 137 919  240 HOH HOH H . 
Q 10 HOH 138 920  242 HOH HOH H . 
Q 10 HOH 139 921  243 HOH HOH H . 
Q 10 HOH 140 922  246 HOH HOH H . 
Q 10 HOH 141 923  250 HOH HOH H . 
Q 10 HOH 142 924  251 HOH HOH H . 
Q 10 HOH 143 925  252 HOH HOH H . 
Q 10 HOH 144 926  255 HOH HOH H . 
Q 10 HOH 145 927  259 HOH HOH H . 
Q 10 HOH 146 928  260 HOH HOH H . 
Q 10 HOH 147 929  261 HOH HOH H . 
Q 10 HOH 148 930  262 HOH HOH H . 
Q 10 HOH 149 931  263 HOH HOH H . 
Q 10 HOH 150 932  264 HOH HOH H . 
Q 10 HOH 151 933  266 HOH HOH H . 
Q 10 HOH 152 934  278 HOH HOH H . 
Q 10 HOH 153 935  283 HOH HOH H . 
Q 10 HOH 154 936  284 HOH HOH H . 
Q 10 HOH 155 937  286 HOH HOH H . 
Q 10 HOH 156 938  287 HOH HOH H . 
Q 10 HOH 157 939  290 HOH HOH H . 
Q 10 HOH 158 940  292 HOH HOH H . 
Q 10 HOH 159 941  295 HOH HOH H . 
Q 10 HOH 160 942  296 HOH HOH H . 
Q 10 HOH 161 943  297 HOH HOH H . 
Q 10 HOH 162 944  299 HOH HOH H . 
Q 10 HOH 163 945  300 HOH HOH H . 
Q 10 HOH 164 946  303 HOH HOH H . 
Q 10 HOH 165 947  304 HOH HOH H . 
Q 10 HOH 166 948  305 HOH HOH H . 
Q 10 HOH 167 949  308 HOH HOH H . 
Q 10 HOH 168 950  315 HOH HOH H . 
Q 10 HOH 169 951  317 HOH HOH H . 
Q 10 HOH 170 952  319 HOH HOH H . 
Q 10 HOH 171 953  321 HOH HOH H . 
Q 10 HOH 172 954  323 HOH HOH H . 
Q 10 HOH 173 955  325 HOH HOH H . 
Q 10 HOH 174 956  327 HOH HOH H . 
Q 10 HOH 175 957  330 HOH HOH H . 
Q 10 HOH 176 958  332 HOH HOH H . 
Q 10 HOH 177 959  335 HOH HOH H . 
Q 10 HOH 178 960  336 HOH HOH H . 
Q 10 HOH 179 961  337 HOH HOH H . 
Q 10 HOH 180 962  338 HOH HOH H . 
Q 10 HOH 181 963  340 HOH HOH H . 
Q 10 HOH 182 964  341 HOH HOH H . 
Q 10 HOH 183 965  343 HOH HOH H . 
Q 10 HOH 184 966  344 HOH HOH H . 
Q 10 HOH 185 967  348 HOH HOH H . 
Q 10 HOH 186 968  349 HOH HOH H . 
Q 10 HOH 187 969  352 HOH HOH H . 
Q 10 HOH 188 970  353 HOH HOH H . 
Q 10 HOH 189 971  354 HOH HOH H . 
Q 10 HOH 190 972  355 HOH HOH H . 
Q 10 HOH 191 973  356 HOH HOH H . 
Q 10 HOH 192 974  358 HOH HOH H . 
Q 10 HOH 193 975  360 HOH HOH H . 
Q 10 HOH 194 976  364 HOH HOH H . 
Q 10 HOH 195 977  365 HOH HOH H . 
Q 10 HOH 196 978  367 HOH HOH H . 
Q 10 HOH 197 979  369 HOH HOH H . 
Q 10 HOH 198 980  373 HOH HOH H . 
Q 10 HOH 199 981  374 HOH HOH H . 
Q 10 HOH 200 982  375 HOH HOH H . 
Q 10 HOH 201 983  376 HOH HOH H . 
Q 10 HOH 202 984  381 HOH HOH H . 
Q 10 HOH 203 985  382 HOH HOH H . 
Q 10 HOH 204 986  386 HOH HOH H . 
Q 10 HOH 205 987  387 HOH HOH H . 
Q 10 HOH 206 988  388 HOH HOH H . 
Q 10 HOH 207 989  390 HOH HOH H . 
Q 10 HOH 208 990  391 HOH HOH H . 
Q 10 HOH 209 991  393 HOH HOH H . 
Q 10 HOH 210 992  394 HOH HOH H . 
Q 10 HOH 211 993  395 HOH HOH H . 
Q 10 HOH 212 994  396 HOH HOH H . 
Q 10 HOH 213 995  397 HOH HOH H . 
Q 10 HOH 214 996  398 HOH HOH H . 
Q 10 HOH 215 997  399 HOH HOH H . 
Q 10 HOH 216 998  400 HOH HOH H . 
Q 10 HOH 217 999  401 HOH HOH H . 
Q 10 HOH 218 1000 420 HOH HOH H . 
Q 10 HOH 219 1001 439 HOH HOH H . 
Q 10 HOH 220 1002 440 HOH HOH H . 
Q 10 HOH 221 1003 441 HOH HOH H . 
Q 10 HOH 222 1004 442 HOH HOH H . 
Q 10 HOH 223 1005 443 HOH HOH H . 
Q 10 HOH 224 1006 444 HOH HOH H . 
Q 10 HOH 225 1007 445 HOH HOH H . 
Q 10 HOH 226 1008 446 HOH HOH H . 
Q 10 HOH 227 1009 447 HOH HOH H . 
Q 10 HOH 228 1010 457 HOH HOH H . 
Q 10 HOH 229 1011 460 HOH HOH H . 
Q 10 HOH 230 1012 461 HOH HOH H . 
Q 10 HOH 231 1013 462 HOH HOH H . 
Q 10 HOH 232 1014 463 HOH HOH H . 
Q 10 HOH 233 1015 464 HOH HOH H . 
Q 10 HOH 234 1016 465 HOH HOH H . 
Q 10 HOH 235 1017 466 HOH HOH H . 
Q 10 HOH 236 1018 467 HOH HOH H . 
Q 10 HOH 237 1019 468 HOH HOH H . 
Q 10 HOH 238 1020 469 HOH HOH H . 
Q 10 HOH 239 1021 470 HOH HOH H . 
Q 10 HOH 240 1022 471 HOH HOH H . 
Q 10 HOH 241 1023 472 HOH HOH H . 
Q 10 HOH 242 1024 473 HOH HOH H . 
Q 10 HOH 243 1025 475 HOH HOH H . 
Q 10 HOH 244 1026 476 HOH HOH H . 
Q 10 HOH 245 1027 477 HOH HOH H . 
Q 10 HOH 246 1028 478 HOH HOH H . 
Q 10 HOH 247 1029 479 HOH HOH H . 
Q 10 HOH 248 1030 480 HOH HOH H . 
Q 10 HOH 249 1031 481 HOH HOH H . 
Q 10 HOH 250 1032 482 HOH HOH H . 
Q 10 HOH 251 1033 483 HOH HOH H . 
Q 10 HOH 252 1034 498 HOH HOH H . 
Q 10 HOH 253 1035 499 HOH HOH H . 
Q 10 HOH 254 1036 500 HOH HOH H . 
Q 10 HOH 255 1037 501 HOH HOH H . 
Q 10 HOH 256 1038 502 HOH HOH H . 
Q 10 HOH 257 1039 503 HOH HOH H . 
Q 10 HOH 258 1040 504 HOH HOH H . 
Q 10 HOH 259 1041 505 HOH HOH H . 
Q 10 HOH 260 1042 506 HOH HOH H . 
Q 10 HOH 261 1043 507 HOH HOH H . 
Q 10 HOH 262 1044 508 HOH HOH H . 
Q 10 HOH 263 1045 509 HOH HOH H . 
Q 10 HOH 264 1046 510 HOH HOH H . 
Q 10 HOH 265 1047 511 HOH HOH H . 
Q 10 HOH 266 1048 512 HOH HOH H . 
Q 10 HOH 267 1049 523 HOH HOH H . 
Q 10 HOH 268 1050 487 HOH HOH H . 
Q 10 HOH 269 1051 38  HOH HOH H . 
Q 10 HOH 270 1052 148 HOH HOH H . 
Q 10 HOH 271 1053 392 HOH HOH H . 
Q 10 HOH 272 1054 434 HOH HOH H . 
R 10 HOH 1   392  14  HOH HOH I . 
R 10 HOH 2   393  19  HOH HOH I . 
R 10 HOH 3   394  55  HOH HOH I . 
R 10 HOH 4   395  61  HOH HOH I . 
R 10 HOH 5   396  64  HOH HOH I . 
R 10 HOH 6   397  68  HOH HOH I . 
R 10 HOH 7   398  81  HOH HOH I . 
R 10 HOH 8   399  82  HOH HOH I . 
R 10 HOH 9   400  86  HOH HOH I . 
R 10 HOH 10  401  92  HOH HOH I . 
R 10 HOH 11  402  98  HOH HOH I . 
R 10 HOH 12  403  100 HOH HOH I . 
R 10 HOH 13  404  108 HOH HOH I . 
R 10 HOH 14  405  114 HOH HOH I . 
R 10 HOH 15  406  116 HOH HOH I . 
R 10 HOH 16  407  122 HOH HOH I . 
R 10 HOH 17  408  129 HOH HOH I . 
R 10 HOH 18  409  130 HOH HOH I . 
R 10 HOH 19  410  132 HOH HOH I . 
R 10 HOH 20  411  134 HOH HOH I . 
R 10 HOH 21  412  138 HOH HOH I . 
R 10 HOH 22  413  146 HOH HOH I . 
R 10 HOH 23  414  147 HOH HOH I . 
R 10 HOH 24  415  149 HOH HOH I . 
R 10 HOH 25  416  150 HOH HOH I . 
R 10 HOH 26  417  154 HOH HOH I . 
R 10 HOH 27  418  157 HOH HOH I . 
R 10 HOH 28  419  166 HOH HOH I . 
R 10 HOH 29  420  167 HOH HOH I . 
R 10 HOH 30  421  168 HOH HOH I . 
R 10 HOH 31  422  170 HOH HOH I . 
R 10 HOH 32  423  173 HOH HOH I . 
R 10 HOH 33  424  174 HOH HOH I . 
R 10 HOH 34  425  175 HOH HOH I . 
R 10 HOH 35  426  177 HOH HOH I . 
R 10 HOH 36  427  179 HOH HOH I . 
R 10 HOH 37  428  180 HOH HOH I . 
R 10 HOH 38  429  183 HOH HOH I . 
R 10 HOH 39  430  184 HOH HOH I . 
R 10 HOH 40  431  190 HOH HOH I . 
R 10 HOH 41  432  193 HOH HOH I . 
R 10 HOH 42  433  194 HOH HOH I . 
R 10 HOH 43  434  196 HOH HOH I . 
R 10 HOH 44  435  197 HOH HOH I . 
R 10 HOH 45  436  198 HOH HOH I . 
R 10 HOH 46  437  203 HOH HOH I . 
R 10 HOH 47  438  205 HOH HOH I . 
R 10 HOH 48  439  210 HOH HOH I . 
R 10 HOH 49  440  211 HOH HOH I . 
R 10 HOH 50  441  217 HOH HOH I . 
R 10 HOH 51  442  220 HOH HOH I . 
R 10 HOH 52  443  221 HOH HOH I . 
R 10 HOH 53  444  222 HOH HOH I . 
R 10 HOH 54  445  227 HOH HOH I . 
R 10 HOH 55  446  228 HOH HOH I . 
R 10 HOH 56  447  231 HOH HOH I . 
R 10 HOH 57  448  236 HOH HOH I . 
R 10 HOH 58  449  238 HOH HOH I . 
R 10 HOH 59  450  245 HOH HOH I . 
R 10 HOH 60  451  247 HOH HOH I . 
R 10 HOH 61  452  248 HOH HOH I . 
R 10 HOH 62  453  249 HOH HOH I . 
R 10 HOH 63  454  254 HOH HOH I . 
R 10 HOH 64  455  256 HOH HOH I . 
R 10 HOH 65  456  257 HOH HOH I . 
R 10 HOH 66  457  258 HOH HOH I . 
R 10 HOH 67  458  265 HOH HOH I . 
R 10 HOH 68  459  267 HOH HOH I . 
R 10 HOH 69  460  268 HOH HOH I . 
R 10 HOH 70  461  270 HOH HOH I . 
R 10 HOH 71  462  271 HOH HOH I . 
R 10 HOH 72  463  272 HOH HOH I . 
R 10 HOH 73  464  273 HOH HOH I . 
R 10 HOH 74  465  275 HOH HOH I . 
R 10 HOH 75  466  277 HOH HOH I . 
R 10 HOH 76  467  281 HOH HOH I . 
R 10 HOH 77  468  282 HOH HOH I . 
R 10 HOH 78  469  285 HOH HOH I . 
R 10 HOH 79  470  288 HOH HOH I . 
R 10 HOH 80  471  289 HOH HOH I . 
R 10 HOH 81  472  291 HOH HOH I . 
R 10 HOH 82  473  293 HOH HOH I . 
R 10 HOH 83  474  294 HOH HOH I . 
R 10 HOH 84  475  298 HOH HOH I . 
R 10 HOH 85  476  301 HOH HOH I . 
R 10 HOH 86  477  306 HOH HOH I . 
R 10 HOH 87  478  307 HOH HOH I . 
R 10 HOH 88  479  309 HOH HOH I . 
R 10 HOH 89  480  310 HOH HOH I . 
R 10 HOH 90  481  311 HOH HOH I . 
R 10 HOH 91  482  312 HOH HOH I . 
R 10 HOH 92  483  314 HOH HOH I . 
R 10 HOH 93  484  320 HOH HOH I . 
R 10 HOH 94  485  322 HOH HOH I . 
R 10 HOH 95  486  324 HOH HOH I . 
R 10 HOH 96  487  326 HOH HOH I . 
R 10 HOH 97  489  331 HOH HOH I . 
R 10 HOH 98  490  333 HOH HOH I . 
R 10 HOH 99  491  339 HOH HOH I . 
R 10 HOH 100 492  342 HOH HOH I . 
R 10 HOH 101 493  346 HOH HOH I . 
R 10 HOH 102 494  350 HOH HOH I . 
R 10 HOH 103 495  351 HOH HOH I . 
R 10 HOH 104 496  357 HOH HOH I . 
R 10 HOH 105 497  359 HOH HOH I . 
R 10 HOH 106 498  361 HOH HOH I . 
R 10 HOH 107 499  362 HOH HOH I . 
R 10 HOH 108 500  363 HOH HOH I . 
R 10 HOH 109 501  366 HOH HOH I . 
R 10 HOH 110 502  368 HOH HOH I . 
R 10 HOH 111 503  370 HOH HOH I . 
R 10 HOH 112 504  402 HOH HOH I . 
R 10 HOH 113 505  403 HOH HOH I . 
R 10 HOH 114 506  404 HOH HOH I . 
R 10 HOH 115 507  405 HOH HOH I . 
R 10 HOH 116 508  406 HOH HOH I . 
R 10 HOH 117 509  407 HOH HOH I . 
R 10 HOH 118 510  408 HOH HOH I . 
R 10 HOH 119 511  409 HOH HOH I . 
R 10 HOH 120 512  410 HOH HOH I . 
R 10 HOH 121 513  411 HOH HOH I . 
R 10 HOH 122 514  412 HOH HOH I . 
R 10 HOH 123 515  413 HOH HOH I . 
R 10 HOH 124 516  414 HOH HOH I . 
R 10 HOH 125 517  415 HOH HOH I . 
R 10 HOH 126 518  416 HOH HOH I . 
R 10 HOH 127 519  417 HOH HOH I . 
R 10 HOH 128 520  418 HOH HOH I . 
R 10 HOH 129 521  419 HOH HOH I . 
R 10 HOH 130 522  421 HOH HOH I . 
R 10 HOH 131 523  422 HOH HOH I . 
R 10 HOH 132 524  423 HOH HOH I . 
R 10 HOH 133 525  424 HOH HOH I . 
R 10 HOH 134 526  425 HOH HOH I . 
R 10 HOH 135 527  426 HOH HOH I . 
R 10 HOH 136 528  427 HOH HOH I . 
R 10 HOH 137 529  428 HOH HOH I . 
R 10 HOH 138 530  429 HOH HOH I . 
R 10 HOH 139 531  430 HOH HOH I . 
R 10 HOH 140 532  431 HOH HOH I . 
R 10 HOH 141 533  432 HOH HOH I . 
R 10 HOH 142 534  448 HOH HOH I . 
R 10 HOH 143 535  449 HOH HOH I . 
R 10 HOH 144 536  450 HOH HOH I . 
R 10 HOH 145 537  451 HOH HOH I . 
R 10 HOH 146 538  452 HOH HOH I . 
R 10 HOH 147 539  453 HOH HOH I . 
R 10 HOH 148 540  474 HOH HOH I . 
R 10 HOH 149 541  484 HOH HOH I . 
R 10 HOH 150 542  485 HOH HOH I . 
R 10 HOH 151 543  486 HOH HOH I . 
R 10 HOH 152 545  488 HOH HOH I . 
R 10 HOH 153 546  489 HOH HOH I . 
R 10 HOH 154 547  490 HOH HOH I . 
R 10 HOH 155 548  491 HOH HOH I . 
R 10 HOH 156 549  492 HOH HOH I . 
R 10 HOH 157 550  493 HOH HOH I . 
R 10 HOH 158 551  494 HOH HOH I . 
R 10 HOH 159 552  513 HOH HOH I . 
R 10 HOH 160 553  514 HOH HOH I . 
R 10 HOH 161 554  515 HOH HOH I . 
R 10 HOH 162 555  516 HOH HOH I . 
R 10 HOH 163 556  517 HOH HOH I . 
R 10 HOH 164 557  518 HOH HOH I . 
R 10 HOH 165 558  519 HOH HOH I . 
R 10 HOH 166 559  520 HOH HOH I . 
R 10 HOH 167 560  521 HOH HOH I . 
R 10 HOH 168 561  522 HOH HOH I . 
# 
_pdbx_struct_mod_residue.id               1 
_pdbx_struct_mod_residue.label_asym_id    B 
_pdbx_struct_mod_residue.label_comp_id    ASN 
_pdbx_struct_mod_residue.label_seq_id     53 
_pdbx_struct_mod_residue.auth_asym_id     H 
_pdbx_struct_mod_residue.auth_comp_id     ASN 
_pdbx_struct_mod_residue.auth_seq_id      60 
_pdbx_struct_mod_residue.PDB_ins_code     G 
_pdbx_struct_mod_residue.parent_comp_id   ASN 
_pdbx_struct_mod_residue.details          'GLYCOSYLATION SITE' 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 8420  ? 
1 MORE         -46.2 ? 
1 'SSA (A^2)'  27630 ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2008-04-22 
2 'Structure model' 1 1 2011-07-13 
3 'Structure model' 1 2 2018-04-11 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Non-polymer description'   
2 2 'Structure model' 'Version format compliance' 
3 3 'Structure model' Advisory                    
4 3 'Structure model' 'Data collection'           
5 3 'Structure model' 'Database references'       
6 3 'Structure model' 'Source and taxonomy'       
7 3 'Structure model' 'Structure summary'         
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1  3 'Structure model' entity                          
2  3 'Structure model' entity_name_com                 
3  3 'Structure model' entity_src_gen                  
4  3 'Structure model' pdbx_distant_solvent_atoms      
5  3 'Structure model' pdbx_entry_details              
6  3 'Structure model' pdbx_unobs_or_zero_occ_atoms    
7  3 'Structure model' pdbx_unobs_or_zero_occ_residues 
8  3 'Structure model' struct_ref                      
9  3 'Structure model' struct_ref_seq                  
10 3 'Structure model' struct_ref_seq_dif              
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  3 'Structure model' '_entity.pdbx_description'                    
2  3 'Structure model' '_entity.src_method'                          
3  3 'Structure model' '_pdbx_entry_details.sequence_details'        
4  3 'Structure model' '_pdbx_unobs_or_zero_occ_atoms.label_asym_id' 
5  3 'Structure model' '_struct_ref.db_code'                         
6  3 'Structure model' '_struct_ref.db_name'                         
7  3 'Structure model' '_struct_ref.pdbx_align_begin'                
8  3 'Structure model' '_struct_ref.pdbx_db_accession'               
9  3 'Structure model' '_struct_ref.pdbx_seq_one_letter_code'        
10 3 'Structure model' '_struct_ref_seq.db_align_beg'                
11 3 'Structure model' '_struct_ref_seq.db_align_end'                
12 3 'Structure model' '_struct_ref_seq.pdbx_auth_seq_align_beg'     
13 3 'Structure model' '_struct_ref_seq.pdbx_db_accession'           
14 3 'Structure model' '_struct_ref_seq.seq_align_beg'               
# 
loop_
_software.name 
_software.classification 
_software.version 
_software.citation_id 
_software.pdbx_ordinal 
CNS    refinement        1.0     ? 1 
ADSC   'data collection' Quantum ? 2 
MOSFLM 'data reduction'  .       ? 3 
SCALA  'data scaling'    .       ? 4 
PHASER phasing           .       ? 5 
# 
_pdbx_entry_details.sequence_details     'Natural variant at this position' 
_pdbx_entry_details.entry_id             3B9F 
_pdbx_entry_details.compound_details     ? 
_pdbx_entry_details.source_details       ? 
_pdbx_entry_details.nonpolymer_details   ? 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             C 
_pdbx_validate_rmsd_angle.auth_asym_id_1             H 
_pdbx_validate_rmsd_angle.auth_comp_id_1             LYS 
_pdbx_validate_rmsd_angle.auth_seq_id_1              185 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             A 
_pdbx_validate_rmsd_angle.auth_atom_id_2             N 
_pdbx_validate_rmsd_angle.auth_asym_id_2             H 
_pdbx_validate_rmsd_angle.auth_comp_id_2             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_2              186 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             A 
_pdbx_validate_rmsd_angle.auth_atom_id_3             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_3             H 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PRO 
_pdbx_validate_rmsd_angle.auth_seq_id_3              186 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             A 
_pdbx_validate_rmsd_angle.angle_value                141.43 
_pdbx_validate_rmsd_angle.angle_target_value         127.00 
_pdbx_validate_rmsd_angle.angle_deviation            14.43 
_pdbx_validate_rmsd_angle.angle_standard_deviation   2.40 
_pdbx_validate_rmsd_angle.linker_flag                Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE L 7   ? ? -132.07 -87.73  
2  1 SER H 36  A ? 32.96   76.02   
3  1 TYR H 60  A ? -160.56 91.15   
4  1 ASN H 60  G ? -156.15 75.45   
5  1 HIS H 71  ? ? -127.86 -51.27  
6  1 ASN H 78  ? A 60.14   -1.80   
7  1 ILE H 79  ? ? -134.97 -56.40  
8  1 GLU H 97  A ? -122.20 -69.19  
9  1 LYS H 185 ? A 11.33   -132.96 
10 1 PRO H 186 ? A -46.24  -8.55   
11 1 ASP H 186 A A -113.02 64.90   
12 1 GLU H 186 B A -148.13 -22.98  
13 1 SER H 214 ? ? -113.13 -128.41 
14 1 SER I 66  ? ? 48.16   -140.94 
15 1 SER I 84  ? ? -172.66 145.09  
16 1 PRO I 102 ? ? -56.63  80.42   
17 1 ASP I 104 ? ? -56.55  72.89   
18 1 SER I 146 ? ? -41.12  -72.13  
19 1 LYS I 187 ? ? -166.02 109.46  
20 1 ARG I 219 ? ? -175.37 119.02  
21 1 ASP I 221 ? ? -174.57 -177.82 
22 1 SER I 232 ? ? 65.99   63.06   
23 1 GLN I 241 ? ? -63.28  99.16   
24 1 ASN I 322 ? ? -92.60  49.14   
25 1 ALA I 344 ? ? 58.49   85.57   
26 1 ALA I 345 ? ? 173.76  176.37  
27 1 ALA I 346 ? ? 36.46   -151.88 
28 1 THR I 347 ? ? 69.08   -163.12 
29 1 ASP I 375 ? ? -123.77 -116.40 
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? L HOH 80  ? 6.07 . 
2 1 O ? L HOH 488 ? 7.01 . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 H SER 36  A OG  ? B SER 22  OG  
2   1 Y 1 H LYS 87  ? CE  ? B LYS 83  CE  
3   1 Y 1 H LYS 87  ? NZ  ? B LYS 83  NZ  
4   1 Y 1 H LYS 110 ? CD  ? B LYS 107 CD  
5   1 Y 1 H LYS 110 ? CE  ? B LYS 107 CE  
6   1 Y 1 H LYS 110 ? NZ  ? B LYS 107 NZ  
7   1 Y 1 H LYS 145 ? CD  ? B LYS 145 CD  
8   1 Y 1 H LYS 145 ? CE  ? B LYS 145 CE  
9   1 Y 1 H LYS 145 ? NZ  ? B LYS 145 NZ  
10  1 Y 1 H LYS 149 ? CG  ? B LYS 154 CG  
11  1 Y 1 H LYS 149 ? CD  ? B LYS 154 CD  
12  1 Y 1 H LYS 149 ? CE  ? B LYS 154 CE  
13  1 Y 1 H LYS 149 ? NZ  ? B LYS 154 NZ  
14  1 Y 1 H ASP 186 A CG  ? B ASP 193 CG  
15  1 Y 1 H ASP 186 A OD1 ? B ASP 193 OD1 
16  1 Y 1 H ASP 186 A OD2 ? B ASP 193 OD2 
17  1 Y 1 H LYS 236 ? CD  ? B LYS 248 CD  
18  1 Y 1 H LYS 236 ? CE  ? B LYS 248 CE  
19  1 Y 1 H LYS 236 ? NZ  ? B LYS 248 NZ  
20  1 Y 1 H LYS 240 ? CD  ? B LYS 252 CD  
21  1 Y 1 H LYS 240 ? CE  ? B LYS 252 CE  
22  1 Y 1 H LYS 240 ? NZ  ? B LYS 252 NZ  
23  1 Y 1 I ASP 28  ? CG  ? C ASP 36  CG  
24  1 Y 1 I ASP 28  ? OD1 ? C ASP 36  OD1 
25  1 Y 1 I ASP 28  ? OD2 ? C ASP 36  OD2 
26  1 Y 1 I SER 43  ? OG  ? C SER 51  OG  
27  1 Y 1 I SER 83  ? OG  ? C SER 91  OG  
28  1 Y 1 I LYS 86  ? CG  ? C LYS 94  CG  
29  1 Y 1 I LYS 86  ? CD  ? C LYS 94  CD  
30  1 Y 1 I LYS 86  ? CE  ? C LYS 94  CE  
31  1 Y 1 I LYS 86  ? NZ  ? C LYS 94  NZ  
32  1 Y 1 I GLU 87  ? CG  ? C GLU 95  CG  
33  1 Y 1 I GLU 87  ? CD  ? C GLU 95  CD  
34  1 Y 1 I GLU 87  ? OE1 ? C GLU 95  OE1 
35  1 Y 1 I GLU 87  ? OE2 ? C GLU 95  OE2 
36  1 Y 1 I ARG 90  ? CG  ? C ARG 98  CG  
37  1 Y 1 I ARG 90  ? CD  ? C ARG 98  CD  
38  1 Y 1 I ARG 90  ? NE  ? C ARG 98  NE  
39  1 Y 1 I ARG 90  ? CZ  ? C ARG 98  CZ  
40  1 Y 1 I ARG 90  ? NH1 ? C ARG 98  NH1 
41  1 Y 1 I ARG 90  ? NH2 ? C ARG 98  NH2 
42  1 Y 1 I ASN 100 ? CG  ? C ASN 108 CG  
43  1 Y 1 I ASN 100 ? OD1 ? C ASN 108 OD1 
44  1 Y 1 I ASN 100 ? ND2 ? C ASN 108 ND2 
45  1 Y 1 I GLN 101 ? CG  ? C GLN 109 CG  
46  1 Y 1 I GLN 101 ? CD  ? C GLN 109 CD  
47  1 Y 1 I GLN 101 ? OE1 ? C GLN 109 OE1 
48  1 Y 1 I GLN 101 ? NE2 ? C GLN 109 NE2 
49  1 Y 1 I ARG 103 ? NE  ? C ARG 111 NE  
50  1 Y 1 I ARG 103 ? CZ  ? C ARG 111 CZ  
51  1 Y 1 I ARG 103 ? NH1 ? C ARG 111 NH1 
52  1 Y 1 I ARG 103 ? NH2 ? C ARG 111 NH2 
53  1 Y 1 I LYS 162 ? CG  ? C LYS 170 CG  
54  1 Y 1 I LYS 162 ? CD  ? C LYS 170 CD  
55  1 Y 1 I LYS 162 ? CE  ? C LYS 170 CE  
56  1 Y 1 I LYS 162 ? NZ  ? C LYS 170 NZ  
57  1 Y 1 I LYS 164 ? CD  ? C LYS 172 CD  
58  1 Y 1 I LYS 164 ? CE  ? C LYS 172 CE  
59  1 Y 1 I LYS 164 ? NZ  ? C LYS 172 NZ  
60  1 Y 1 I ASP 173 ? CG  ? C ASP 181 CG  
61  1 Y 1 I ASP 173 ? OD1 ? C ASP 181 OD1 
62  1 Y 1 I ASP 173 ? OD2 ? C ASP 181 OD2 
63  1 Y 1 I LYS 187 ? CE  ? C LYS 195 CE  
64  1 Y 1 I LYS 187 ? NZ  ? C LYS 195 NZ  
65  1 Y 1 I LYS 197 ? CG  ? C LYS 205 CG  
66  1 Y 1 I LYS 197 ? CD  ? C LYS 205 CD  
67  1 Y 1 I LYS 197 ? CE  ? C LYS 205 CE  
68  1 Y 1 I LYS 197 ? NZ  ? C LYS 205 NZ  
69  1 Y 1 I SER 208 ? OG  ? C SER 216 OG  
70  1 Y 1 I GLU 209 ? CG  ? C GLU 217 CG  
71  1 Y 1 I GLU 209 ? CD  ? C GLU 217 CD  
72  1 Y 1 I GLU 209 ? OE1 ? C GLU 217 OE1 
73  1 Y 1 I GLU 209 ? OE2 ? C GLU 217 OE2 
74  1 Y 1 I ARG 229 ? CG  ? C ARG 237 CG  
75  1 Y 1 I ARG 229 ? CD  ? C ARG 237 CD  
76  1 Y 1 I ARG 229 ? NE  ? C ARG 237 NE  
77  1 Y 1 I ARG 229 ? CZ  ? C ARG 237 CZ  
78  1 Y 1 I ARG 229 ? NH1 ? C ARG 237 NH1 
79  1 Y 1 I ARG 229 ? NH2 ? C ARG 237 NH2 
80  1 Y 1 I GLN 241 ? CG  ? C GLN 249 CG  
81  1 Y 1 I GLN 241 ? CD  ? C GLN 249 CD  
82  1 Y 1 I GLN 241 ? OE1 ? C GLN 249 OE1 
83  1 Y 1 I GLN 241 ? NE2 ? C GLN 249 NE2 
84  1 Y 1 I ASN 243 ? CG  ? C ASN 251 CG  
85  1 Y 1 I ASN 243 ? OD1 ? C ASN 251 OD1 
86  1 Y 1 I ASN 243 ? ND2 ? C ASN 251 ND2 
87  1 Y 1 I LYS 266 ? CD  ? C LYS 274 CD  
88  1 Y 1 I LYS 266 ? CE  ? C LYS 274 CE  
89  1 Y 1 I LYS 266 ? NZ  ? C LYS 274 NZ  
90  1 Y 1 I ARG 269 ? CG  ? C ARG 277 CG  
91  1 Y 1 I ARG 269 ? CD  ? C ARG 277 CD  
92  1 Y 1 I ARG 269 ? NE  ? C ARG 277 NE  
93  1 Y 1 I ARG 269 ? CZ  ? C ARG 277 CZ  
94  1 Y 1 I ARG 269 ? NH1 ? C ARG 277 NH1 
95  1 Y 1 I ARG 269 ? NH2 ? C ARG 277 NH2 
96  1 Y 1 I LYS 273 ? CD  ? C LYS 281 CD  
97  1 Y 1 I LYS 273 ? CE  ? C LYS 281 CE  
98  1 Y 1 I LYS 273 ? NZ  ? C LYS 281 NZ  
99  1 Y 1 I LYS 286 ? CE  ? C LYS 294 CE  
100 1 Y 1 I LYS 286 ? NZ  ? C LYS 294 NZ  
101 1 Y 1 I ARG 342 ? CG  ? C ARG 350 CG  
102 1 Y 1 I ARG 342 ? CD  ? C ARG 350 CD  
103 1 Y 1 I ARG 342 ? NE  ? C ARG 350 NE  
104 1 Y 1 I ARG 342 ? CZ  ? C ARG 350 CZ  
105 1 Y 1 I ARG 342 ? NH1 ? C ARG 350 NH1 
106 1 Y 1 I ARG 342 ? NH2 ? C ARG 350 NH2 
107 1 Y 1 I THR 347 ? OG1 ? C THR 355 OG1 
108 1 Y 1 I THR 347 ? CG2 ? C THR 355 CG2 
109 1 Y 1 I ARG 386 ? CD  ? C ARG 394 CD  
110 1 Y 1 I ARG 386 ? NE  ? C ARG 394 NE  
111 1 Y 1 I ARG 386 ? CZ  ? C ARG 394 CZ  
112 1 Y 1 I ARG 386 ? NH1 ? C ARG 394 NH1 
113 1 Y 1 I ARG 386 ? NH2 ? C ARG 394 NH2 
114 1 N 1 H SGN 1   ? S2  ? F SGN 1   S2  
115 1 N 1 H SGN 1   ? O4S ? F SGN 1   O4S 
116 1 N 1 H SGN 1   ? O5S ? F SGN 1   O5S 
117 1 N 1 H SGN 1   ? O6S ? F SGN 1   O6S 
118 1 N 1 H IDS 2   ? O4  ? F IDS 2   O4  
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 L THR -2  ? A THR 1   
2  1 Y 1 L ALA -1  ? A ALA 2   
3  1 Y 1 L THR 0   ? A THR 3   
4  1 Y 1 L GLY 15  ? A GLY 48  
5  1 Y 1 L ARG 16  ? A ARG 49  
6  1 Y 1 H TRP 147 A B TRP 148 
7  1 Y 1 H THR 147 B B THR 149 
8  1 Y 1 H ALA 147 C B ALA 150 
9  1 Y 1 H ASN 147 D B ASN 151 
10 1 Y 1 H VAL 147 E B VAL 152 
11 1 Y 1 H GLY 147 F B GLY 153 
12 1 Y 1 I MET -7  ? C MET 1   
13 1 Y 1 I GLY -6  ? C GLY 2   
14 1 Y 1 I HIS -5  ? C HIS 3   
15 1 Y 1 I HIS -4  ? C HIS 4   
16 1 Y 1 I HIS -3  ? C HIS 5   
17 1 Y 1 I HIS -2  ? C HIS 6   
18 1 Y 1 I HIS -1  ? C HIS 7   
19 1 Y 1 I HIS 0   ? C HIS 8   
20 1 Y 1 I HIS 1   ? C HIS 9   
21 1 Y 1 I HIS 2   ? C HIS 10  
22 1 Y 1 I HIS 3   ? C HIS 11  
23 1 Y 1 I HIS 4   ? C HIS 12  
24 1 Y 1 I SER 5   ? C SER 13  
25 1 Y 1 I SER 6   ? C SER 14  
26 1 Y 1 I GLY 7   ? C GLY 15  
27 1 Y 1 I HIS 8   ? C HIS 16  
28 1 Y 1 I ILE 9   ? C ILE 17  
29 1 Y 1 I ASP 10  ? C ASP 18  
30 1 Y 1 I ASP 11  ? C ASP 19  
31 1 Y 1 I ASP 12  ? C ASP 20  
32 1 Y 1 I ASP 13  ? C ASP 21  
33 1 Y 1 I LYS 14  ? C LYS 22  
34 1 Y 1 I HIS 15  ? C HIS 23  
35 1 Y 1 I MET 16  ? C MET 24  
36 1 Y 1 I VAL 17  ? C VAL 25  
37 1 Y 1 I GLY 18  ? C GLY 26  
38 1 Y 1 I ALA 19  ? C ALA 27  
39 1 Y 1 I THR 20  ? C THR 28  
40 1 Y 1 I VAL 21  ? C VAL 29  
41 1 Y 1 I ALA 22  ? C ALA 30  
42 1 Y 1 I PRO 23  ? C PRO 31  
43 1 Y 1 I SER 24  ? C SER 32  
44 1 Y 1 I SER 25  ? C SER 33  
45 1 Y 1 I ARG 26  ? C ARG 34  
46 1 Y 1 I ARG 27  ? C ARG 35  
47 1 Y 1 I ASN 79  ? C ASN 87  
48 1 Y 1 I LEU 80  ? C LEU 88  
49 1 Y 1 I GLN 81  ? C GLN 89  
50 1 Y 1 I LYS 82  ? C LYS 90  
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4  N-ACETYL-D-GLUCOSAMINE                  NAG 
5  ALPHA-L-FUCOSE                          FUC 
6  N,O6-DISULFO-GLUCOSAMINE                SGN 
7  '2-O-sulfo-alpha-L-idopyranuronic acid' IDS 
8  'SULFATE ION'                           SO4 
9  GLYCEROL                                GOL 
10 water                                   HOH 
#