data_2QQW # _entry.id 2QQW # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.287 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2QQW RCSB RCSB043942 WWPDB D_1000043942 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 2AC1 'Crystal structure of a cell-wall invertase from Arabidopsis thaliana' unspecified PDB 2OXB 'Crystal structure of a cell-wall invertase (E203Q) from Arabidopsis thaliana in complex with sucrose' unspecified PDB 2QQV . unspecified # _pdbx_database_status.entry_id 2QQW _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2007-07-27 _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Lammens, W.' 1 'Le Roy, K.' 2 'Van Laere, A.' 3 'Rabijns, A.' 4 'Van den Ende, W.' 5 # _citation.id primary _citation.title 'Crystal structures of Arabidopsis thaliana cell-wall invertase mutants in complex with sucrose.' _citation.journal_abbrev J.Mol.Biol. _citation.journal_volume 377 _citation.page_first 378 _citation.page_last 385 _citation.year 2008 _citation.journal_id_ASTM JMOBAK _citation.country UK _citation.journal_id_ISSN 0022-2836 _citation.journal_id_CSD 0070 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 18258263 _citation.pdbx_database_id_DOI 10.1016/j.jmb.2007.12.074 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Lammens, W.' 1 primary 'Le Roy, K.' 2 primary 'Van Laere, A.' 3 primary 'Rabijns, A.' 4 primary 'Van den Ende, W.' 5 # _cell.entry_id 2QQW _cell.length_a 105.877 _cell.length_b 105.877 _cell.length_c 50.479 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 120.00 _cell.Z_PDB 3 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2QQW _symmetry.space_group_name_H-M 'P 32' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 145 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man Beta-fructofuranosidase 61059.023 1 3.2.1.26 D23A ? ? 2 non-polymer syn N-ACETYL-D-GLUCOSAMINE 221.208 5 ? ? ? ? 3 non-polymer man ALPHA-D-MANNOSE 180.156 4 ? ? ? ? 4 non-polymer man SUCROSE 342.296 1 ? ? ? ? 5 non-polymer syn 'ZINC ION' 65.409 4 ? ? ? ? 6 water nat water 18.015 19 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Putative beta-fructofuranosidase 1' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;NQPYRTGFHFQPPKNWMNAPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAPFDINGCWSG SATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVI IGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHD YYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWL DRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNV SVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLRALID HSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQIS ; _entity_poly.pdbx_seq_one_letter_code_can ;NQPYRTGFHFQPPKNWMNAPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAPFDINGCWSG SATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVI IGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHD YYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWL DRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNV SVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLRALID HSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQIS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ASN n 1 2 GLN n 1 3 PRO n 1 4 TYR n 1 5 ARG n 1 6 THR n 1 7 GLY n 1 8 PHE n 1 9 HIS n 1 10 PHE n 1 11 GLN n 1 12 PRO n 1 13 PRO n 1 14 LYS n 1 15 ASN n 1 16 TRP n 1 17 MET n 1 18 ASN n 1 19 ALA n 1 20 PRO n 1 21 ASN n 1 22 GLY n 1 23 PRO n 1 24 MET n 1 25 ILE n 1 26 TYR n 1 27 LYS n 1 28 GLY n 1 29 ILE n 1 30 TYR n 1 31 HIS n 1 32 LEU n 1 33 PHE n 1 34 TYR n 1 35 GLN n 1 36 TRP n 1 37 ASN n 1 38 PRO n 1 39 LYS n 1 40 GLY n 1 41 ALA n 1 42 VAL n 1 43 TRP n 1 44 GLY n 1 45 ASN n 1 46 ILE n 1 47 VAL n 1 48 TRP n 1 49 ALA n 1 50 HIS n 1 51 SER n 1 52 THR n 1 53 SER n 1 54 THR n 1 55 ASP n 1 56 LEU n 1 57 ILE n 1 58 ASN n 1 59 TRP n 1 60 ASP n 1 61 PRO n 1 62 HIS n 1 63 PRO n 1 64 PRO n 1 65 ALA n 1 66 ILE n 1 67 PHE n 1 68 PRO n 1 69 SER n 1 70 ALA n 1 71 PRO n 1 72 PHE n 1 73 ASP n 1 74 ILE n 1 75 ASN n 1 76 GLY n 1 77 CYS n 1 78 TRP n 1 79 SER n 1 80 GLY n 1 81 SER n 1 82 ALA n 1 83 THR n 1 84 ILE n 1 85 LEU n 1 86 PRO n 1 87 ASN n 1 88 GLY n 1 89 LYS n 1 90 PRO n 1 91 VAL n 1 92 ILE n 1 93 LEU n 1 94 TYR n 1 95 THR n 1 96 GLY n 1 97 ILE n 1 98 ASP n 1 99 PRO n 1 100 LYS n 1 101 ASN n 1 102 GLN n 1 103 GLN n 1 104 VAL n 1 105 GLN n 1 106 ASN n 1 107 ILE n 1 108 ALA n 1 109 GLU n 1 110 PRO n 1 111 LYS n 1 112 ASN n 1 113 LEU n 1 114 SER n 1 115 ASP n 1 116 PRO n 1 117 TYR n 1 118 LEU n 1 119 ARG n 1 120 GLU n 1 121 TRP n 1 122 LYS n 1 123 LYS n 1 124 SER n 1 125 PRO n 1 126 LEU n 1 127 ASN n 1 128 PRO n 1 129 LEU n 1 130 MET n 1 131 ALA n 1 132 PRO n 1 133 ASP n 1 134 ALA n 1 135 VAL n 1 136 ASN n 1 137 GLY n 1 138 ILE n 1 139 ASN n 1 140 ALA n 1 141 SER n 1 142 SER n 1 143 PHE n 1 144 ARG n 1 145 ASP n 1 146 PRO n 1 147 THR n 1 148 THR n 1 149 ALA n 1 150 TRP n 1 151 LEU n 1 152 GLY n 1 153 GLN n 1 154 ASP n 1 155 LYS n 1 156 LYS n 1 157 TRP n 1 158 ARG n 1 159 VAL n 1 160 ILE n 1 161 ILE n 1 162 GLY n 1 163 SER n 1 164 LYS n 1 165 ILE n 1 166 HIS n 1 167 ARG n 1 168 ARG n 1 169 GLY n 1 170 LEU n 1 171 ALA n 1 172 ILE n 1 173 THR n 1 174 TYR n 1 175 THR n 1 176 SER n 1 177 LYS n 1 178 ASP n 1 179 PHE n 1 180 LEU n 1 181 LYS n 1 182 TRP n 1 183 GLU n 1 184 LYS n 1 185 SER n 1 186 PRO n 1 187 GLU n 1 188 PRO n 1 189 LEU n 1 190 HIS n 1 191 TYR n 1 192 ASP n 1 193 ASP n 1 194 GLY n 1 195 SER n 1 196 GLY n 1 197 MET n 1 198 TRP n 1 199 GLU n 1 200 CYS n 1 201 PRO n 1 202 ASP n 1 203 PHE n 1 204 PHE n 1 205 PRO n 1 206 VAL n 1 207 THR n 1 208 ARG n 1 209 PHE n 1 210 GLY n 1 211 SER n 1 212 ASN n 1 213 GLY n 1 214 VAL n 1 215 GLU n 1 216 THR n 1 217 SER n 1 218 SER n 1 219 PHE n 1 220 GLY n 1 221 GLU n 1 222 PRO n 1 223 ASN n 1 224 GLU n 1 225 ILE n 1 226 LEU n 1 227 LYS n 1 228 HIS n 1 229 VAL n 1 230 LEU n 1 231 LYS n 1 232 ILE n 1 233 SER n 1 234 LEU n 1 235 ASP n 1 236 ASP n 1 237 THR n 1 238 LYS n 1 239 HIS n 1 240 ASP n 1 241 TYR n 1 242 TYR n 1 243 THR n 1 244 ILE n 1 245 GLY n 1 246 THR n 1 247 TYR n 1 248 ASP n 1 249 ARG n 1 250 VAL n 1 251 LYS n 1 252 ASP n 1 253 LYS n 1 254 PHE n 1 255 VAL n 1 256 PRO n 1 257 ASP n 1 258 ASN n 1 259 GLY n 1 260 PHE n 1 261 LYS n 1 262 MET n 1 263 ASP n 1 264 GLY n 1 265 THR n 1 266 ALA n 1 267 PRO n 1 268 ARG n 1 269 TYR n 1 270 ASP n 1 271 TYR n 1 272 GLY n 1 273 LYS n 1 274 TYR n 1 275 TYR n 1 276 ALA n 1 277 SER n 1 278 LYS n 1 279 THR n 1 280 PHE n 1 281 PHE n 1 282 ASP n 1 283 SER n 1 284 ALA n 1 285 LYS n 1 286 ASN n 1 287 ARG n 1 288 ARG n 1 289 ILE n 1 290 LEU n 1 291 TRP n 1 292 GLY n 1 293 TRP n 1 294 THR n 1 295 ASN n 1 296 GLU n 1 297 SER n 1 298 SER n 1 299 SER n 1 300 VAL n 1 301 GLU n 1 302 ASP n 1 303 ASP n 1 304 VAL n 1 305 GLU n 1 306 LYS n 1 307 GLY n 1 308 TRP n 1 309 SER n 1 310 GLY n 1 311 ILE n 1 312 GLN n 1 313 THR n 1 314 ILE n 1 315 PRO n 1 316 ARG n 1 317 LYS n 1 318 ILE n 1 319 TRP n 1 320 LEU n 1 321 ASP n 1 322 ARG n 1 323 SER n 1 324 GLY n 1 325 LYS n 1 326 GLN n 1 327 LEU n 1 328 ILE n 1 329 GLN n 1 330 TRP n 1 331 PRO n 1 332 VAL n 1 333 ARG n 1 334 GLU n 1 335 VAL n 1 336 GLU n 1 337 ARG n 1 338 LEU n 1 339 ARG n 1 340 THR n 1 341 LYS n 1 342 GLN n 1 343 VAL n 1 344 LYS n 1 345 ASN n 1 346 LEU n 1 347 ARG n 1 348 ASN n 1 349 LYS n 1 350 VAL n 1 351 LEU n 1 352 LYS n 1 353 SER n 1 354 GLY n 1 355 SER n 1 356 ARG n 1 357 LEU n 1 358 GLU n 1 359 VAL n 1 360 TYR n 1 361 GLY n 1 362 VAL n 1 363 THR n 1 364 ALA n 1 365 ALA n 1 366 GLN n 1 367 ALA n 1 368 ASP n 1 369 VAL n 1 370 GLU n 1 371 VAL n 1 372 LEU n 1 373 PHE n 1 374 LYS n 1 375 VAL n 1 376 ARG n 1 377 ASP n 1 378 LEU n 1 379 GLU n 1 380 LYS n 1 381 ALA n 1 382 ASP n 1 383 VAL n 1 384 ILE n 1 385 GLU n 1 386 PRO n 1 387 SER n 1 388 TRP n 1 389 THR n 1 390 ASP n 1 391 PRO n 1 392 GLN n 1 393 LEU n 1 394 ILE n 1 395 CYS n 1 396 SER n 1 397 LYS n 1 398 MET n 1 399 ASN n 1 400 VAL n 1 401 SER n 1 402 VAL n 1 403 LYS n 1 404 SER n 1 405 GLY n 1 406 LEU n 1 407 GLY n 1 408 PRO n 1 409 PHE n 1 410 GLY n 1 411 LEU n 1 412 MET n 1 413 VAL n 1 414 LEU n 1 415 ALA n 1 416 SER n 1 417 LYS n 1 418 ASN n 1 419 LEU n 1 420 GLU n 1 421 GLU n 1 422 TYR n 1 423 THR n 1 424 SER n 1 425 VAL n 1 426 TYR n 1 427 PHE n 1 428 ARG n 1 429 ILE n 1 430 PHE n 1 431 LYS n 1 432 ALA n 1 433 ARG n 1 434 GLN n 1 435 ASN n 1 436 SER n 1 437 ASN n 1 438 LYS n 1 439 TYR n 1 440 VAL n 1 441 VAL n 1 442 LEU n 1 443 MET n 1 444 CYS n 1 445 SER n 1 446 ASP n 1 447 GLN n 1 448 SER n 1 449 ARG n 1 450 SER n 1 451 SER n 1 452 LEU n 1 453 LYS n 1 454 GLU n 1 455 ASP n 1 456 ASN n 1 457 ASP n 1 458 LYS n 1 459 THR n 1 460 THR n 1 461 TYR n 1 462 GLY n 1 463 ALA n 1 464 PHE n 1 465 VAL n 1 466 ASP n 1 467 ILE n 1 468 ASN n 1 469 PRO n 1 470 HIS n 1 471 GLN n 1 472 PRO n 1 473 LEU n 1 474 SER n 1 475 LEU n 1 476 ARG n 1 477 ALA n 1 478 LEU n 1 479 ILE n 1 480 ASP n 1 481 HIS n 1 482 SER n 1 483 VAL n 1 484 VAL n 1 485 GLU n 1 486 SER n 1 487 PHE n 1 488 GLY n 1 489 GLY n 1 490 LYS n 1 491 GLY n 1 492 ARG n 1 493 ALA n 1 494 CYS n 1 495 ILE n 1 496 THR n 1 497 SER n 1 498 ARG n 1 499 VAL n 1 500 TYR n 1 501 PRO n 1 502 LYS n 1 503 LEU n 1 504 ALA n 1 505 ILE n 1 506 GLY n 1 507 LYS n 1 508 SER n 1 509 SER n 1 510 HIS n 1 511 LEU n 1 512 PHE n 1 513 ALA n 1 514 PHE n 1 515 ASN n 1 516 TYR n 1 517 GLY n 1 518 TYR n 1 519 GLN n 1 520 SER n 1 521 VAL n 1 522 ASP n 1 523 VAL n 1 524 LEU n 1 525 ASN n 1 526 LEU n 1 527 ASN n 1 528 ALA n 1 529 TRP n 1 530 SER n 1 531 MET n 1 532 ASN n 1 533 SER n 1 534 ALA n 1 535 GLN n 1 536 ILE n 1 537 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'thale cress' _entity_src_gen.gene_src_genus Arabidopsis _entity_src_gen.pdbx_gene_src_gene ATBFRUCT1 _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Arabidopsis thaliana' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 3702 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name ? _entity_src_gen.pdbx_host_org_scientific_name 'Pichia pastoris' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 4922 _entity_src_gen.host_org_genus Pichia _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain ? _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type ? _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name ? _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code Q43866_ARATH _struct_ref.pdbx_db_accession Q43866 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;NQPYRTGFHFQPPKNWMNDPNGPMIYKGIYHLFYQWNPKGAVWGNIVWAHSTSTDLINWDPHPPAIFPSAPFDINGCWSG SATILPNGKPVILYTGIDPKNQQVQNIAEPKNLSDPYLREWKKSPLNPLMAPDAVNGINASSFRDPTTAWLGQDKKWRVI IGSKIHRRGLAITYTSKDFLKWEKSPEPLHYDDGSGMWECPDFFPVTRFGSNGVETSSFGEPNEILKHVLKISLDDTKHD YYTIGTYDRVKDKFVPDNGFKMDGTAPRYDYGKYYASKTFFDSAKNRRILWGWTNESSSVEDDVEKGWSGIQTIPRKIWL DRSGKQLIQWPVREVERLRTKQVKNLRNKVLKSGSRLEVYGVTAAQADVEVLFKVRDLEKADVIEPSWTDPQLICSKMNV SVKSGLGPFGLMVLASKNLEEYTSVYFRIFKARQNSNKYVVLMCSDQSRSSLKEDNDKTTYGAFVDINPHQPLSLRALID HSVVESFGGKGRACITSRVYPKLAIGKSSHLFAFNYGYQSVDVLNLNAWSMNSAQIS ; _struct_ref.pdbx_align_begin 48 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 2QQW _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 537 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q43866 _struct_ref_seq.db_align_beg 48 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 584 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 5 _struct_ref_seq.pdbx_auth_seq_align_end 541 # _struct_ref_seq_dif.align_id 1 _struct_ref_seq_dif.pdbx_pdb_id_code 2QQW _struct_ref_seq_dif.mon_id ALA _struct_ref_seq_dif.pdbx_pdb_strand_id A _struct_ref_seq_dif.seq_num 19 _struct_ref_seq_dif.pdbx_pdb_ins_code ? _struct_ref_seq_dif.pdbx_seq_db_name UNP _struct_ref_seq_dif.pdbx_seq_db_accession_code Q43866 _struct_ref_seq_dif.db_mon_id ASP _struct_ref_seq_dif.pdbx_seq_db_seq_num 66 _struct_ref_seq_dif.details ENGINEERED _struct_ref_seq_dif.pdbx_auth_seq_num 23 _struct_ref_seq_dif.pdbx_ordinal 1 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SUC saccharide . SUCROSE ? 'C12 H22 O11' 342.296 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.entry_id 2QQW _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.68 _exptl_crystal.density_percent_sol 54.02 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 277 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_details '0.1M sodium cacodylate, 0.1M zinc acetate, 22.5% PEG 8000, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'MAR CCD 165 mm' _diffrn_detector.pdbx_collection_date 2006-11-22 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator 'Fixed exit double crystal Si [111], horizontally focussing' _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.0332 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'EMBL/DESY, HAMBURG BEAMLINE BW7A' _diffrn_source.pdbx_synchrotron_site 'EMBL/DESY, Hamburg' _diffrn_source.pdbx_synchrotron_beamline BW7A _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.0332 # _reflns.entry_id 2QQW _reflns.observed_criterion_sigma_I 1.41 _reflns.observed_criterion_sigma_F 2.0 _reflns.d_resolution_low 30.0 _reflns.d_resolution_high 2.80 _reflns.number_obs 12825 _reflns.number_all 15532 _reflns.percent_possible_obs 99.4 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 3.4 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 2.80 _reflns_shell.d_res_low 2.85 _reflns_shell.percent_possible_all 100 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy 3.3 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2QQW _refine.ls_number_reflns_obs 12825 _refine.ls_number_reflns_all ? _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 28.57 _refine.ls_d_res_high 2.80 _refine.ls_percent_reflns_obs 99.40 _refine.ls_R_factor_obs 0.19153 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.18831 _refine.ls_R_factor_R_free 0.25231 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.0 _refine.ls_number_reflns_R_free 776 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.942 _refine.correlation_coeff_Fo_to_Fc_free 0.898 _refine.B_iso_mean 45.498 _refine.aniso_B[1][1] 0.00 _refine.aniso_B[2][2] 0.00 _refine.aniso_B[3][3] 0.01 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.20 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model 'pdb entry 2AC1' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free 0.395 _refine.overall_SU_ML 0.300 _refine.overall_SU_B 15.384 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 4287 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 141 _refine_hist.number_atoms_solvent 19 _refine_hist.number_atoms_total 4447 _refine_hist.d_res_high 2.80 _refine_hist.d_res_low 28.57 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.009 0.022 ? 4561 'X-RAY DIFFRACTION' ? r_bond_other_d ? ? ? ? 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.333 1.977 ? 6212 'X-RAY DIFFRACTION' ? r_angle_other_deg ? ? ? ? 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.065 5.000 ? 532 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 37.206 23.873 ? 204 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 17.367 15.000 ? 731 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 14.211 15.000 ? 25 'X-RAY DIFFRACTION' ? r_chiral_restr 0.085 0.200 ? 676 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.003 0.020 ? 3420 'X-RAY DIFFRACTION' ? r_gen_planes_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbd_refined 0.206 0.200 ? 2027 'X-RAY DIFFRACTION' ? r_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_nbtor_refined 0.312 0.200 ? 3059 'X-RAY DIFFRACTION' ? r_nbtor_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.149 0.200 ? 164 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_refined ? ? ? ? 'X-RAY DIFFRACTION' ? r_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.209 0.200 ? 21 'X-RAY DIFFRACTION' ? r_symmetry_vdw_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.163 0.200 ? 3 'X-RAY DIFFRACTION' ? r_symmetry_hbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_refined 0.020 0.200 ? 1 'X-RAY DIFFRACTION' ? r_symmetry_metal_ion_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcbond_it 0.495 1.500 ? 2719 'X-RAY DIFFRACTION' ? r_mcbond_other ? ? ? ? 'X-RAY DIFFRACTION' ? r_mcangle_it 0.894 2.000 ? 4323 'X-RAY DIFFRACTION' ? r_scbond_it 0.905 3.000 ? 2121 'X-RAY DIFFRACTION' ? r_scangle_it 1.533 4.500 ? 1889 'X-RAY DIFFRACTION' ? r_rigid_bond_restr ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_free ? ? ? ? 'X-RAY DIFFRACTION' ? r_sphericity_bonded ? ? ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 2.80 _refine_ls_shell.d_res_low 2.870 _refine_ls_shell.number_reflns_R_work 1093 _refine_ls_shell.R_factor_R_work 0.351 _refine_ls_shell.percent_reflns_obs 100.00 _refine_ls_shell.R_factor_R_free 0.422 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 61 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 2QQW _struct.title 'Crystal structure of a cell-wall invertase (D23A) from Arabidopsis thaliana in complex with sucrose' _struct.pdbx_descriptor 'Beta-fructofuranosidase (E.C.3.2.1.26)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2QQW _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text 'hydrolase, invertase, Glycosidase' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 2 ? D N N 3 ? E N N 3 ? F N N 3 ? G N N 3 ? H N N 2 ? I N N 2 ? J N N 2 ? K N N 4 ? L N N 5 ? M N N 5 ? N N N 5 ? O N N 5 ? P N N 6 ? # _struct_biol.id 1 _struct_biol.details ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 SER A 299 ? GLY A 307 ? SER A 303 GLY A 311 1 ? 9 HELX_P HELX_P2 2 ARG A 333 ? ARG A 339 ? ARG A 337 ARG A 343 5 ? 7 HELX_P HELX_P3 3 ASP A 377 ? ALA A 381 ? ASP A 381 ALA A 385 5 ? 5 HELX_P HELX_P4 4 ASP A 390 ? MET A 398 ? ASP A 394 MET A 402 1 ? 9 HELX_P HELX_P5 5 ILE A 505 ? SER A 509 ? ILE A 509 SER A 513 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 395 SG ? ? ? 1_555 A CYS 444 SG ? ? A CYS 399 A CYS 448 1_555 ? ? ? ? ? ? ? 2.039 ? metalc1 metalc ? ? A ASP 60 OD2 ? ? ? 1_555 O ZN . ZN ? ? A ASP 64 A ZN 1104 1_555 ? ? ? ? ? ? ? 2.261 ? covale1 covale ? ? A ASN 112 ND2 ? ? ? 1_555 J NAG . C1 ? ? A ASN 116 A NAG 770 1_555 ? ? ? ? ? ? ? 1.444 ? covale2 covale ? ? A ASN 139 ND2 ? ? ? 1_555 H NAG . C1 ? ? A ASN 143 A NAG 790 1_555 ? ? ? ? ? ? ? 1.451 ? metalc2 metalc ? ? A HIS 190 NE2 ? ? ? 1_555 M ZN . ZN ? ? A HIS 194 A ZN 1102 1_555 ? ? ? ? ? ? ? 2.287 ? metalc3 metalc ? ? A ASP 192 OD1 ? ? ? 1_555 M ZN . ZN ? ? A ASP 196 A ZN 1102 1_555 ? ? ? ? ? ? ? 2.313 ? metalc4 metalc ? ? A ASP 192 OD2 ? ? ? 1_555 M ZN . ZN ? ? A ASP 196 A ZN 1102 1_555 ? ? ? ? ? ? ? 2.355 ? covale3 covale ? ? A ASN 295 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 299 A NAG 750 1_555 ? ? ? ? ? ? ? 1.433 ? metalc5 metalc ? ? A HIS 470 NE2 ? ? ? 1_555 L ZN . ZN ? ? A HIS 474 A ZN 1101 1_555 ? ? ? ? ? ? ? 2.190 ? covale4 covale ? ? B NAG . O4 ? ? ? 1_555 C NAG . C1 ? ? A NAG 750 A NAG 751 1_555 ? ? ? ? ? ? ? 1.432 ? covale5 covale ? ? C NAG . O4 ? ? ? 1_555 D MAN . C1 ? ? A NAG 751 A MAN 752 1_555 ? ? ? ? ? ? ? 1.451 ? covale6 covale ? ? D MAN . O3 ? ? ? 1_555 G MAN . C1 ? ? A MAN 752 A MAN 755 1_555 ? ? ? ? ? ? ? 1.458 ? covale7 covale ? ? D MAN . O6 ? ? ? 1_555 E MAN . C1 ? ? A MAN 752 A MAN 753 1_555 ? ? ? ? ? ? ? 1.429 ? covale8 covale ? ? E MAN . O2 ? ? ? 1_555 F MAN . C1 ? ? A MAN 753 A MAN 754 1_555 ? ? ? ? ? ? ? 1.441 ? covale9 covale ? ? H NAG . O4 ? ? ? 1_555 I NAG . C1 ? ? A NAG 790 A NAG 791 1_555 ? ? ? ? ? ? ? 1.459 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 ASN 127 A . ? ASN 131 A PRO 128 A ? PRO 132 A 1 -1.66 2 ASN 258 A . ? ASN 262 A GLY 259 A ? GLY 263 A 1 0.56 3 GLY 259 A . ? GLY 263 A PHE 260 A ? PHE 264 A 1 -12.49 4 GLY 264 A . ? GLY 268 A THR 265 A ? THR 269 A 1 3.20 5 GLY 407 A . ? GLY 411 A PRO 408 A ? PRO 412 A 1 3.14 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 5 ? B ? 4 ? C ? 4 ? D ? 4 ? E ? 4 ? F ? 3 ? G ? 4 ? H ? 6 ? I ? 5 ? J ? 6 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel A 2 3 ? anti-parallel A 3 4 ? anti-parallel A 4 5 ? parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel C 3 4 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel G 1 2 ? anti-parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 ASP A 60 ? ILE A 66 ? ASP A 64 ILE A 70 A 2 VAL A 47 ? SER A 53 ? VAL A 51 SER A 57 A 3 ILE A 29 ? ASN A 37 ? ILE A 33 ASN A 41 A 4 ASN A 15 ? TYR A 26 ? ASN A 19 TYR A 30 A 5 TRP A 308 ? SER A 309 ? TRP A 312 SER A 313 B 1 CYS A 77 ? ILE A 84 ? CYS A 81 ILE A 88 B 2 PRO A 90 ? ILE A 97 ? PRO A 94 ILE A 101 B 3 GLN A 103 ? PRO A 110 ? GLN A 107 PRO A 114 B 4 TRP A 121 ? LYS A 123 ? TRP A 125 LYS A 127 C 1 PHE A 143 ? PRO A 146 ? PHE A 147 PRO A 150 C 2 TRP A 157 ? LYS A 164 ? TRP A 161 LYS A 168 C 3 GLY A 169 ? SER A 176 ? GLY A 173 SER A 180 C 4 TRP A 182 ? LYS A 184 ? TRP A 186 LYS A 188 D 1 TRP A 150 ? LEU A 151 ? TRP A 154 LEU A 155 D 2 TRP A 157 ? LYS A 164 ? TRP A 161 LYS A 168 D 3 GLY A 169 ? SER A 176 ? GLY A 173 SER A 180 D 4 TYR A 191 ? ASP A 192 ? TYR A 195 ASP A 196 E 1 TRP A 198 ? THR A 207 ? TRP A 202 THR A 211 E 2 LEU A 226 ? LEU A 234 ? LEU A 230 LEU A 238 E 3 HIS A 239 ? ASP A 248 ? HIS A 243 ASP A 252 E 4 LYS A 253 ? PRO A 256 ? LYS A 257 PRO A 260 F 1 TYR A 275 ? ASP A 282 ? TYR A 279 ASP A 286 F 2 ARG A 287 ? THR A 294 ? ARG A 291 THR A 298 F 3 ILE A 311 ? GLN A 312 ? ILE A 315 GLN A 316 G 1 TYR A 275 ? ASP A 282 ? TYR A 279 ASP A 286 G 2 ARG A 287 ? THR A 294 ? ARG A 291 THR A 298 G 3 ARG A 316 ? LEU A 320 ? ARG A 320 LEU A 324 G 4 LEU A 327 ? PRO A 331 ? LEU A 331 PRO A 335 H 1 LYS A 344 ? LEU A 351 ? LYS A 348 LEU A 355 H 2 VAL A 521 ? SER A 530 ? VAL A 525 SER A 534 H 3 GLN A 366 ? LYS A 374 ? GLN A 370 LYS A 378 H 4 LEU A 473 ? ASP A 480 ? LEU A 477 ASP A 484 H 5 VAL A 483 ? GLY A 488 ? VAL A 487 GLY A 492 H 6 ALA A 493 ? ARG A 498 ? ALA A 497 ARG A 502 I 1 SER A 355 ? VAL A 359 ? SER A 359 VAL A 363 I 2 HIS A 510 ? ASN A 515 ? HIS A 514 ASN A 519 I 3 LEU A 406 ? ALA A 415 ? LEU A 410 ALA A 419 I 4 THR A 423 ? LYS A 431 ? THR A 427 LYS A 435 I 5 ASP A 382 ? VAL A 383 ? ASP A 386 VAL A 387 J 1 SER A 355 ? VAL A 359 ? SER A 359 VAL A 363 J 2 HIS A 510 ? ASN A 515 ? HIS A 514 ASN A 519 J 3 LEU A 406 ? ALA A 415 ? LEU A 410 ALA A 419 J 4 THR A 423 ? LYS A 431 ? THR A 427 LYS A 435 J 5 TYR A 439 ? ASP A 446 ? TYR A 443 ASP A 450 J 6 TYR A 461 ? VAL A 465 ? TYR A 465 VAL A 469 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 O ASP A 60 ? O ASP A 64 N THR A 52 ? N THR A 56 A 2 3 O VAL A 47 ? O VAL A 51 N TRP A 36 ? N TRP A 40 A 3 4 O PHE A 33 ? O PHE A 37 N ASN A 21 ? N ASN A 25 A 4 5 N MET A 17 ? N MET A 21 O SER A 309 ? O SER A 313 B 1 2 N THR A 83 ? N THR A 87 O VAL A 91 ? O VAL A 95 B 2 3 N TYR A 94 ? N TYR A 98 O ASN A 106 ? O ASN A 110 B 3 4 N GLU A 109 ? N GLU A 113 O LYS A 122 ? O LYS A 126 C 1 2 N ARG A 144 ? N ARG A 148 O GLY A 162 ? O GLY A 166 C 2 3 N TRP A 157 ? N TRP A 161 O SER A 176 ? O SER A 180 C 3 4 N THR A 175 ? N THR A 179 O GLU A 183 ? O GLU A 187 D 1 2 N TRP A 150 ? N TRP A 154 O ARG A 158 ? O ARG A 162 D 2 3 N TRP A 157 ? N TRP A 161 O SER A 176 ? O SER A 180 D 3 4 N GLY A 169 ? N GLY A 173 O ASP A 192 ? O ASP A 196 E 1 2 N GLU A 199 ? N GLU A 203 O SER A 233 ? O SER A 237 E 2 3 N HIS A 228 ? N HIS A 232 O GLY A 245 ? O GLY A 249 E 3 4 N THR A 246 ? N THR A 250 O VAL A 255 ? O VAL A 259 F 1 2 N LYS A 278 ? N LYS A 282 O TRP A 291 ? O TRP A 295 F 2 3 N THR A 294 ? N THR A 298 O ILE A 311 ? O ILE A 315 G 1 2 N LYS A 278 ? N LYS A 282 O TRP A 291 ? O TRP A 295 G 2 3 N LEU A 290 ? N LEU A 294 O ARG A 316 ? O ARG A 320 G 3 4 N LYS A 317 ? N LYS A 321 O TRP A 330 ? O TRP A 334 H 1 2 N LYS A 349 ? N LYS A 353 O VAL A 523 ? O VAL A 527 H 2 3 O TRP A 529 ? O TRP A 533 N ASP A 368 ? N ASP A 372 H 3 4 N ALA A 367 ? N ALA A 371 O ILE A 479 ? O ILE A 483 H 4 5 N ARG A 476 ? N ARG A 480 O PHE A 487 ? O PHE A 491 H 5 6 N SER A 486 ? N SER A 490 O ILE A 495 ? O ILE A 499 I 1 2 N VAL A 359 ? N VAL A 363 O LEU A 511 ? O LEU A 515 I 2 3 O PHE A 512 ? O PHE A 516 N MET A 412 ? N MET A 416 I 3 4 N VAL A 413 ? N VAL A 417 O THR A 423 ? O THR A 427 I 4 5 O LYS A 431 ? O LYS A 435 N ASP A 382 ? N ASP A 386 J 1 2 N VAL A 359 ? N VAL A 363 O LEU A 511 ? O LEU A 515 J 2 3 O PHE A 512 ? O PHE A 516 N MET A 412 ? N MET A 416 J 3 4 N VAL A 413 ? N VAL A 417 O THR A 423 ? O THR A 427 J 4 5 N SER A 424 ? N SER A 428 O ASP A 446 ? O ASP A 450 J 5 6 N SER A 445 ? N SER A 449 O TYR A 461 ? O TYR A 465 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE NAG A 750' AC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 751' AC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE MAN A 752' AC4 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE MAN A 753' AC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 790' AC7 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 770' AC8 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE SUC A 800' AC9 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE ZN A 1101' BC1 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE ZN A 1102' BC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE ZN A 1104' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 8 LYS A 238 ? LYS A 242 . ? 1_555 ? 2 AC1 8 LYS A 273 ? LYS A 277 . ? 1_555 ? 3 AC1 8 TYR A 275 ? TYR A 279 . ? 1_555 ? 4 AC1 8 TRP A 293 ? TRP A 297 . ? 1_555 ? 5 AC1 8 ASN A 295 ? ASN A 299 . ? 1_555 ? 6 AC1 8 GLU A 296 ? GLU A 300 . ? 1_555 ? 7 AC1 8 SER A 297 ? SER A 301 . ? 1_555 ? 8 AC1 8 ASP A 457 ? ASP A 461 . ? 1_555 ? 9 AC2 3 ASP A 457 ? ASP A 461 . ? 1_555 ? 10 AC2 3 THR A 459 ? THR A 463 . ? 1_555 ? 11 AC2 3 HOH P . ? HOH A 1002 . ? 1_555 ? 12 AC3 1 THR A 459 ? THR A 463 . ? 1_555 ? 13 AC4 1 SER A 396 ? SER A 400 . ? 1_555 ? 14 AC6 5 ASN A 139 ? ASN A 143 . ? 1_555 ? 15 AC6 5 SER A 142 ? SER A 146 . ? 1_555 ? 16 AC6 5 LYS A 164 ? LYS A 168 . ? 1_555 ? 17 AC6 5 ILE A 165 ? ILE A 169 . ? 1_555 ? 18 AC6 5 GLN A 535 ? GLN A 539 . ? 1_554 ? 19 AC7 2 ASN A 112 ? ASN A 116 . ? 1_555 ? 20 AC7 2 SER A 114 ? SER A 118 . ? 1_555 ? 21 AC8 10 ASN A 18 ? ASN A 22 . ? 1_555 ? 22 AC8 10 GLN A 35 ? GLN A 39 . ? 1_555 ? 23 AC8 10 TRP A 43 ? TRP A 47 . ? 1_555 ? 24 AC8 10 TRP A 78 ? TRP A 82 . ? 1_555 ? 25 AC8 10 SER A 79 ? SER A 83 . ? 1_555 ? 26 AC8 10 ARG A 144 ? ARG A 148 . ? 1_555 ? 27 AC8 10 ASP A 145 ? ASP A 149 . ? 1_555 ? 28 AC8 10 GLU A 199 ? GLU A 203 . ? 1_555 ? 29 AC8 10 ASP A 235 ? ASP A 239 . ? 1_555 ? 30 AC8 10 LYS A 238 ? LYS A 242 . ? 1_555 ? 31 AC9 2 GLU A 385 ? GLU A 389 . ? 3_565 ? 32 AC9 2 HIS A 470 ? HIS A 474 . ? 1_555 ? 33 BC1 2 HIS A 190 ? HIS A 194 . ? 1_555 ? 34 BC1 2 ASP A 192 ? ASP A 196 . ? 1_555 ? 35 BC2 2 ASP A 60 ? ASP A 64 . ? 1_555 ? 36 BC2 2 HIS A 166 ? HIS A 170 . ? 1_556 ? # _atom_sites.entry_id 2QQW _atom_sites.fract_transf_matrix[1][1] 0.009445 _atom_sites.fract_transf_matrix[1][2] 0.005453 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.010906 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.019810 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . ASN A 1 1 ? 1.463 12.187 13.252 1.00 52.00 ? 5 ASN A N 1 ATOM 2 C CA . ASN A 1 1 ? 1.026 13.563 13.637 1.00 51.93 ? 5 ASN A CA 1 ATOM 3 C C . ASN A 1 1 ? 0.425 14.311 12.440 1.00 51.45 ? 5 ASN A C 1 ATOM 4 O O . ASN A 1 1 ? 0.811 14.068 11.286 1.00 51.47 ? 5 ASN A O 1 ATOM 5 C CB . ASN A 1 1 ? 2.190 14.361 14.241 1.00 52.22 ? 5 ASN A CB 1 ATOM 6 C CG . ASN A 1 1 ? 1.722 15.396 15.268 1.00 53.44 ? 5 ASN A CG 1 ATOM 7 O OD1 . ASN A 1 1 ? 0.912 16.293 14.967 1.00 54.07 ? 5 ASN A OD1 1 ATOM 8 N ND2 . ASN A 1 1 ? 2.232 15.272 16.492 1.00 53.56 ? 5 ASN A ND2 1 ATOM 9 N N . GLN A 1 2 ? -0.513 15.219 12.719 1.00 50.38 ? 6 GLN A N 1 ATOM 10 C CA . GLN A 1 2 ? -1.292 15.862 11.665 1.00 49.31 ? 6 GLN A CA 1 ATOM 11 C C . GLN A 1 2 ? -1.294 17.403 11.768 1.00 48.78 ? 6 GLN A C 1 ATOM 12 O O . GLN A 1 2 ? -2.318 18.021 12.120 1.00 48.66 ? 6 GLN A O 1 ATOM 13 C CB . GLN A 1 2 ? -2.717 15.288 11.650 1.00 49.27 ? 6 GLN A CB 1 ATOM 14 C CG . GLN A 1 2 ? -2.808 13.830 11.193 1.00 48.38 ? 6 GLN A CG 1 ATOM 15 C CD . GLN A 1 2 ? -2.816 13.665 9.676 1.00 47.56 ? 6 GLN A CD 1 ATOM 16 O OE1 . GLN A 1 2 ? -2.749 14.637 8.927 1.00 47.76 ? 6 GLN A OE1 1 ATOM 17 N NE2 . GLN A 1 2 ? -2.912 12.423 9.222 1.00 46.80 ? 6 GLN A NE2 1 ATOM 18 N N . PRO A 1 3 ? -0.149 18.033 11.433 1.00 47.95 ? 7 PRO A N 1 ATOM 19 C CA . PRO A 1 3 ? 0.019 19.481 11.578 1.00 47.14 ? 7 PRO A CA 1 ATOM 20 C C . PRO A 1 3 ? -0.860 20.299 10.634 1.00 46.50 ? 7 PRO A C 1 ATOM 21 O O . PRO A 1 3 ? -1.035 21.506 10.856 1.00 46.84 ? 7 PRO A O 1 ATOM 22 C CB . PRO A 1 3 ? 1.493 19.698 11.224 1.00 47.17 ? 7 PRO A CB 1 ATOM 23 C CG . PRO A 1 3 ? 1.856 18.554 10.355 1.00 47.33 ? 7 PRO A CG 1 ATOM 24 C CD . PRO A 1 3 ? 1.059 17.395 10.869 1.00 47.85 ? 7 PRO A CD 1 ATOM 25 N N . TYR A 1 4 ? -1.402 19.656 9.597 1.00 45.41 ? 8 TYR A N 1 ATOM 26 C CA . TYR A 1 4 ? -2.207 20.350 8.586 1.00 44.29 ? 8 TYR A CA 1 ATOM 27 C C . TYR A 1 4 ? -3.729 20.200 8.766 1.00 43.69 ? 8 TYR A C 1 ATOM 28 O O . TYR A 1 4 ? -4.509 20.931 8.152 1.00 43.37 ? 8 TYR A O 1 ATOM 29 C CB . TYR A 1 4 ? -1.778 19.919 7.190 1.00 43.95 ? 8 TYR A CB 1 ATOM 30 C CG . TYR A 1 4 ? -0.313 20.137 6.938 1.00 43.99 ? 8 TYR A CG 1 ATOM 31 C CD1 . TYR A 1 4 ? 0.286 21.368 7.217 1.00 44.14 ? 8 TYR A CD1 1 ATOM 32 C CD2 . TYR A 1 4 ? 0.483 19.123 6.411 1.00 44.12 ? 8 TYR A CD2 1 ATOM 33 C CE1 . TYR A 1 4 ? 1.648 21.578 6.991 1.00 43.63 ? 8 TYR A CE1 1 ATOM 34 C CE2 . TYR A 1 4 ? 1.842 19.326 6.176 1.00 43.87 ? 8 TYR A CE2 1 ATOM 35 C CZ . TYR A 1 4 ? 2.415 20.556 6.469 1.00 43.67 ? 8 TYR A CZ 1 ATOM 36 O OH . TYR A 1 4 ? 3.755 20.763 6.235 1.00 44.09 ? 8 TYR A OH 1 ATOM 37 N N . ARG A 1 5 ? -4.140 19.249 9.603 1.00 42.89 ? 9 ARG A N 1 ATOM 38 C CA . ARG A 1 5 ? -5.541 19.110 9.980 1.00 42.24 ? 9 ARG A CA 1 ATOM 39 C C . ARG A 1 5 ? -6.021 20.348 10.725 1.00 41.94 ? 9 ARG A C 1 ATOM 40 O O . ARG A 1 5 ? -5.321 20.886 11.590 1.00 42.05 ? 9 ARG A O 1 ATOM 41 C CB . ARG A 1 5 ? -5.770 17.855 10.827 1.00 41.99 ? 9 ARG A CB 1 ATOM 42 C CG . ARG A 1 5 ? -5.903 16.592 10.002 1.00 41.31 ? 9 ARG A CG 1 ATOM 43 C CD . ARG A 1 5 ? -6.447 15.428 10.812 1.00 39.34 ? 9 ARG A CD 1 ATOM 44 N NE . ARG A 1 5 ? -7.910 15.403 10.874 1.00 37.20 ? 9 ARG A NE 1 ATOM 45 C CZ . ARG A 1 5 ? -8.716 15.010 9.884 1.00 35.71 ? 9 ARG A CZ 1 ATOM 46 N NH1 . ARG A 1 5 ? -8.227 14.618 8.708 1.00 34.81 ? 9 ARG A NH1 1 ATOM 47 N NH2 . ARG A 1 5 ? -10.029 15.020 10.069 1.00 34.82 ? 9 ARG A NH2 1 ATOM 48 N N . THR A 1 6 ? -7.219 20.795 10.375 1.00 41.49 ? 10 THR A N 1 ATOM 49 C CA . THR A 1 6 ? -7.772 22.017 10.933 1.00 40.90 ? 10 THR A CA 1 ATOM 50 C C . THR A 1 6 ? -8.425 21.737 12.284 1.00 40.77 ? 10 THR A C 1 ATOM 51 O O . THR A 1 6 ? -8.929 20.644 12.531 1.00 40.61 ? 10 THR A O 1 ATOM 52 C CB . THR A 1 6 ? -8.771 22.666 9.955 1.00 40.86 ? 10 THR A CB 1 ATOM 53 O OG1 . THR A 1 6 ? -9.840 21.753 9.673 1.00 40.07 ? 10 THR A OG1 1 ATOM 54 C CG2 . THR A 1 6 ? -8.070 23.021 8.654 1.00 40.67 ? 10 THR A CG2 1 ATOM 55 N N . GLY A 1 7 ? -8.399 22.731 13.159 1.00 40.62 ? 11 GLY A N 1 ATOM 56 C CA . GLY A 1 7 ? -9.021 22.606 14.463 1.00 40.32 ? 11 GLY A CA 1 ATOM 57 C C . GLY A 1 7 ? -10.466 23.062 14.514 1.00 40.43 ? 11 GLY A C 1 ATOM 58 O O . GLY A 1 7 ? -11.159 22.751 15.475 1.00 40.80 ? 11 GLY A O 1 ATOM 59 N N . PHE A 1 8 ? -10.930 23.807 13.505 1.00 40.38 ? 12 PHE A N 1 ATOM 60 C CA . PHE A 1 8 ? -12.317 24.312 13.513 1.00 40.19 ? 12 PHE A CA 1 ATOM 61 C C . PHE A 1 8 ? -12.998 24.444 12.139 1.00 39.95 ? 12 PHE A C 1 ATOM 62 O O . PHE A 1 8 ? -14.049 25.086 12.019 1.00 40.06 ? 12 PHE A O 1 ATOM 63 C CB . PHE A 1 8 ? -12.457 25.604 14.347 1.00 40.12 ? 12 PHE A CB 1 ATOM 64 C CG . PHE A 1 8 ? -11.741 26.802 13.768 1.00 40.70 ? 12 PHE A CG 1 ATOM 65 C CD1 . PHE A 1 8 ? -12.414 27.704 12.937 1.00 41.39 ? 12 PHE A CD1 1 ATOM 66 C CD2 . PHE A 1 8 ? -10.405 27.051 14.074 1.00 40.48 ? 12 PHE A CD2 1 ATOM 67 C CE1 . PHE A 1 8 ? -11.762 28.823 12.400 1.00 40.99 ? 12 PHE A CE1 1 ATOM 68 C CE2 . PHE A 1 8 ? -9.747 28.165 13.543 1.00 41.31 ? 12 PHE A CE2 1 ATOM 69 C CZ . PHE A 1 8 ? -10.429 29.051 12.704 1.00 41.18 ? 12 PHE A CZ 1 ATOM 70 N N . HIS A 1 9 ? -12.415 23.822 11.117 1.00 39.51 ? 13 HIS A N 1 ATOM 71 C CA . HIS A 1 9 ? -13.091 23.688 9.815 1.00 39.17 ? 13 HIS A CA 1 ATOM 72 C C . HIS A 1 9 ? -13.709 22.309 9.639 1.00 38.86 ? 13 HIS A C 1 ATOM 73 O O . HIS A 1 9 ? -13.197 21.326 10.163 1.00 39.10 ? 13 HIS A O 1 ATOM 74 C CB . HIS A 1 9 ? -12.129 23.966 8.663 1.00 38.92 ? 13 HIS A CB 1 ATOM 75 C CG . HIS A 1 9 ? -11.926 25.421 8.397 1.00 38.28 ? 13 HIS A CG 1 ATOM 76 N ND1 . HIS A 1 9 ? -11.143 26.220 9.201 1.00 37.19 ? 13 HIS A ND1 1 ATOM 77 C CD2 . HIS A 1 9 ? -12.410 26.223 7.421 1.00 37.82 ? 13 HIS A CD2 1 ATOM 78 C CE1 . HIS A 1 9 ? -11.152 27.453 8.732 1.00 37.63 ? 13 HIS A CE1 1 ATOM 79 N NE2 . HIS A 1 9 ? -11.912 27.482 7.652 1.00 38.07 ? 13 HIS A NE2 1 ATOM 80 N N . PHE A 1 10 ? -14.803 22.232 8.894 1.00 38.46 ? 14 PHE A N 1 ATOM 81 C CA . PHE A 1 10 ? -15.384 20.939 8.624 1.00 38.34 ? 14 PHE A CA 1 ATOM 82 C C . PHE A 1 10 ? -14.527 20.052 7.708 1.00 38.68 ? 14 PHE A C 1 ATOM 83 O O . PHE A 1 10 ? -14.187 20.424 6.576 1.00 38.76 ? 14 PHE A O 1 ATOM 84 C CB . PHE A 1 10 ? -16.793 21.032 8.055 1.00 38.17 ? 14 PHE A CB 1 ATOM 85 C CG . PHE A 1 10 ? -17.428 19.704 7.907 1.00 37.51 ? 14 PHE A CG 1 ATOM 86 C CD1 . PHE A 1 10 ? -18.182 19.171 8.941 1.00 38.11 ? 14 PHE A CD1 1 ATOM 87 C CD2 . PHE A 1 10 ? -17.202 18.941 6.776 1.00 37.28 ? 14 PHE A CD2 1 ATOM 88 C CE1 . PHE A 1 10 ? -18.735 17.906 8.835 1.00 38.43 ? 14 PHE A CE1 1 ATOM 89 C CE2 . PHE A 1 10 ? -17.749 17.682 6.660 1.00 38.24 ? 14 PHE A CE2 1 ATOM 90 C CZ . PHE A 1 10 ? -18.518 17.162 7.694 1.00 38.22 ? 14 PHE A CZ 1 ATOM 91 N N . GLN A 1 11 ? -14.198 18.871 8.220 1.00 38.80 ? 15 GLN A N 1 ATOM 92 C CA . GLN A 1 11 ? -13.598 17.805 7.426 1.00 38.65 ? 15 GLN A CA 1 ATOM 93 C C . GLN A 1 11 ? -13.907 16.472 8.104 1.00 39.02 ? 15 GLN A C 1 ATOM 94 O O . GLN A 1 11 ? -13.999 16.421 9.340 1.00 38.93 ? 15 GLN A O 1 ATOM 95 C CB . GLN A 1 11 ? -12.082 18.006 7.260 1.00 38.63 ? 15 GLN A CB 1 ATOM 96 C CG . GLN A 1 11 ? -11.312 18.227 8.551 1.00 37.72 ? 15 GLN A CG 1 ATOM 97 C CD . GLN A 1 11 ? -9.867 18.596 8.312 1.00 37.91 ? 15 GLN A CD 1 ATOM 98 O OE1 . GLN A 1 11 ? -9.378 19.608 8.816 1.00 37.18 ? 15 GLN A OE1 1 ATOM 99 N NE2 . GLN A 1 11 ? -9.169 17.776 7.539 1.00 37.60 ? 15 GLN A NE2 1 ATOM 100 N N . PRO A 1 12 ? -14.093 15.399 7.304 1.00 39.06 ? 16 PRO A N 1 ATOM 101 C CA . PRO A 1 12 ? -14.266 14.061 7.856 1.00 39.24 ? 16 PRO A CA 1 ATOM 102 C C . PRO A 1 12 ? -13.050 13.640 8.684 1.00 39.48 ? 16 PRO A C 1 ATOM 103 O O . PRO A 1 12 ? -11.955 14.151 8.455 1.00 39.57 ? 16 PRO A O 1 ATOM 104 C CB . PRO A 1 12 ? -14.388 13.176 6.607 1.00 38.93 ? 16 PRO A CB 1 ATOM 105 C CG . PRO A 1 12 ? -13.842 13.975 5.494 1.00 38.74 ? 16 PRO A CG 1 ATOM 106 C CD . PRO A 1 12 ? -14.160 15.385 5.833 1.00 39.13 ? 16 PRO A CD 1 ATOM 107 N N . PRO A 1 13 ? -13.239 12.716 9.644 1.00 39.83 ? 17 PRO A N 1 ATOM 108 C CA . PRO A 1 13 ? -12.112 12.171 10.416 1.00 39.92 ? 17 PRO A CA 1 ATOM 109 C C . PRO A 1 13 ? -10.955 11.675 9.539 1.00 39.96 ? 17 PRO A C 1 ATOM 110 O O . PRO A 1 13 ? -9.819 11.646 9.996 1.00 39.99 ? 17 PRO A O 1 ATOM 111 C CB . PRO A 1 13 ? -12.729 10.986 11.166 1.00 39.69 ? 17 PRO A CB 1 ATOM 112 C CG . PRO A 1 13 ? -14.166 11.237 11.201 1.00 39.60 ? 17 PRO A CG 1 ATOM 113 C CD . PRO A 1 13 ? -14.531 12.133 10.057 1.00 39.82 ? 17 PRO A CD 1 ATOM 114 N N . LYS A 1 14 ? -11.251 11.289 8.300 1.00 40.13 ? 18 LYS A N 1 ATOM 115 C CA . LYS A 1 14 ? -10.231 10.834 7.353 1.00 40.65 ? 18 LYS A CA 1 ATOM 116 C C . LYS A 1 14 ? -10.760 10.839 5.917 1.00 40.55 ? 18 LYS A C 1 ATOM 117 O O . LYS A 1 14 ? -11.961 11.008 5.704 1.00 40.71 ? 18 LYS A O 1 ATOM 118 C CB . LYS A 1 14 ? -9.776 9.416 7.709 1.00 41.10 ? 18 LYS A CB 1 ATOM 119 C CG . LYS A 1 14 ? -10.890 8.367 7.664 1.00 42.30 ? 18 LYS A CG 1 ATOM 120 C CD . LYS A 1 14 ? -10.323 6.957 7.712 1.00 44.27 ? 18 LYS A CD 1 ATOM 121 C CE . LYS A 1 14 ? -11.440 5.917 7.776 1.00 45.39 ? 18 LYS A CE 1 ATOM 122 N NZ . LYS A 1 14 ? -10.913 4.555 7.486 1.00 45.64 ? 18 LYS A NZ 1 ATOM 123 N N . ASN A 1 15 ? -9.865 10.648 4.944 1.00 40.21 ? 19 ASN A N 1 ATOM 124 C CA . ASN A 1 15 ? -10.246 10.367 3.541 1.00 40.07 ? 19 ASN A CA 1 ATOM 125 C C . ASN A 1 15 ? -10.696 11.554 2.698 1.00 39.40 ? 19 ASN A C 1 ATOM 126 O O . ASN A 1 15 ? -10.654 12.693 3.153 1.00 39.80 ? 19 ASN A O 1 ATOM 127 C CB . ASN A 1 15 ? -11.296 9.250 3.455 1.00 40.21 ? 19 ASN A CB 1 ATOM 128 C CG . ASN A 1 15 ? -10.704 7.885 3.666 1.00 40.76 ? 19 ASN A CG 1 ATOM 129 O OD1 . ASN A 1 15 ? -9.633 7.559 3.136 1.00 40.63 ? 19 ASN A OD1 1 ATOM 130 N ND2 . ASN A 1 15 ? -11.398 7.066 4.445 1.00 41.51 ? 19 ASN A ND2 1 ATOM 131 N N . TRP A 1 16 ? -11.131 11.259 1.473 1.00 38.38 ? 20 TRP A N 1 ATOM 132 C CA . TRP A 1 16 ? -11.413 12.270 0.465 1.00 37.59 ? 20 TRP A CA 1 ATOM 133 C C . TRP A 1 16 ? -12.756 12.963 0.645 1.00 37.60 ? 20 TRP A C 1 ATOM 134 O O . TRP A 1 16 ? -13.776 12.306 0.856 1.00 37.69 ? 20 TRP A O 1 ATOM 135 C CB . TRP A 1 16 ? -11.365 11.641 -0.925 1.00 36.84 ? 20 TRP A CB 1 ATOM 136 C CG . TRP A 1 16 ? -11.952 12.524 -1.993 1.00 36.56 ? 20 TRP A CG 1 ATOM 137 C CD1 . TRP A 1 16 ? -13.274 12.627 -2.347 1.00 35.68 ? 20 TRP A CD1 1 ATOM 138 C CD2 . TRP A 1 16 ? -11.242 13.445 -2.834 1.00 36.00 ? 20 TRP A CD2 1 ATOM 139 N NE1 . TRP A 1 16 ? -13.423 13.551 -3.355 1.00 35.64 ? 20 TRP A NE1 1 ATOM 140 C CE2 . TRP A 1 16 ? -12.194 14.066 -3.672 1.00 35.46 ? 20 TRP A CE2 1 ATOM 141 C CE3 . TRP A 1 16 ? -9.895 13.805 -2.958 1.00 35.19 ? 20 TRP A CE3 1 ATOM 142 C CZ2 . TRP A 1 16 ? -11.840 15.018 -4.622 1.00 35.44 ? 20 TRP A CZ2 1 ATOM 143 C CZ3 . TRP A 1 16 ? -9.545 14.756 -3.906 1.00 35.12 ? 20 TRP A CZ3 1 ATOM 144 C CH2 . TRP A 1 16 ? -10.512 15.348 -4.724 1.00 35.36 ? 20 TRP A CH2 1 ATOM 145 N N . MET A 1 17 ? -12.754 14.287 0.521 1.00 37.51 ? 21 MET A N 1 ATOM 146 C CA . MET A 1 17 ? -13.998 15.051 0.446 1.00 37.52 ? 21 MET A CA 1 ATOM 147 C C . MET A 1 17 ? -13.988 16.085 -0.692 1.00 37.89 ? 21 MET A C 1 ATOM 148 O O . MET A 1 17 ? -12.973 16.758 -0.929 1.00 38.34 ? 21 MET A O 1 ATOM 149 C CB . MET A 1 17 ? -14.292 15.739 1.781 1.00 37.66 ? 21 MET A CB 1 ATOM 150 C CG . MET A 1 17 ? -15.580 16.569 1.778 1.00 37.16 ? 21 MET A CG 1 ATOM 151 S SD . MET A 1 17 ? -16.059 17.257 3.379 1.00 36.50 ? 21 MET A SD 1 ATOM 152 C CE . MET A 1 17 ? -14.758 18.461 3.628 1.00 36.09 ? 21 MET A CE 1 ATOM 153 N N . ASN A 1 18 ? -15.108 16.187 -1.409 1.00 37.73 ? 22 ASN A N 1 ATOM 154 C CA . ASN A 1 18 ? -15.335 17.314 -2.303 1.00 37.51 ? 22 ASN A CA 1 ATOM 155 C C . ASN A 1 18 ? -16.664 18.008 -2.008 1.00 37.66 ? 22 ASN A C 1 ATOM 156 O O . ASN A 1 18 ? -16.936 18.301 -0.853 1.00 37.66 ? 22 ASN A O 1 ATOM 157 C CB . ASN A 1 18 ? -15.075 17.001 -3.804 1.00 37.33 ? 22 ASN A CB 1 ATOM 158 C CG . ASN A 1 18 ? -15.963 15.905 -4.367 1.00 37.23 ? 22 ASN A CG 1 ATOM 159 O OD1 . ASN A 1 18 ? -15.868 14.754 -3.965 1.00 38.20 ? 22 ASN A OD1 1 ATOM 160 N ND2 . ASN A 1 18 ? -16.801 16.255 -5.342 1.00 36.51 ? 22 ASN A ND2 1 ATOM 161 N N . ALA A 1 19 ? -17.476 18.258 -3.033 1.00 38.10 ? 23 ALA A N 1 ATOM 162 C CA . ALA A 1 19 ? -18.670 19.102 -2.946 1.00 38.55 ? 23 ALA A CA 1 ATOM 163 C C . ALA A 1 19 ? -19.532 18.895 -1.700 1.00 39.20 ? 23 ALA A C 1 ATOM 164 O O . ALA A 1 19 ? -19.806 17.754 -1.321 1.00 39.55 ? 23 ALA A O 1 ATOM 165 C CB . ALA A 1 19 ? -19.516 18.906 -4.182 1.00 38.40 ? 23 ALA A CB 1 ATOM 166 N N . PRO A 1 20 ? -19.963 19.998 -1.057 1.00 39.59 ? 24 PRO A N 1 ATOM 167 C CA . PRO A 1 20 ? -21.030 19.917 -0.051 1.00 39.88 ? 24 PRO A CA 1 ATOM 168 C C . PRO A 1 20 ? -22.356 19.521 -0.703 1.00 40.12 ? 24 PRO A C 1 ATOM 169 O O . PRO A 1 20 ? -22.688 20.012 -1.783 1.00 40.22 ? 24 PRO A O 1 ATOM 170 C CB . PRO A 1 20 ? -21.120 21.352 0.486 1.00 39.94 ? 24 PRO A CB 1 ATOM 171 C CG . PRO A 1 20 ? -20.559 22.204 -0.603 1.00 39.88 ? 24 PRO A CG 1 ATOM 172 C CD . PRO A 1 20 ? -19.468 21.376 -1.226 1.00 39.60 ? 24 PRO A CD 1 ATOM 173 N N . ASN A 1 21 ? -23.104 18.640 -0.054 1.00 40.43 ? 25 ASN A N 1 ATOM 174 C CA . ASN A 1 21 ? -24.372 18.176 -0.608 1.00 40.60 ? 25 ASN A CA 1 ATOM 175 C C . ASN A 1 21 ? -25.567 18.481 0.293 1.00 40.63 ? 25 ASN A C 1 ATOM 176 O O . ASN A 1 21 ? -25.443 18.499 1.522 1.00 40.66 ? 25 ASN A O 1 ATOM 177 C CB . ASN A 1 21 ? -24.322 16.673 -0.884 1.00 40.56 ? 25 ASN A CB 1 ATOM 178 C CG . ASN A 1 21 ? -23.240 16.289 -1.871 1.00 41.03 ? 25 ASN A CG 1 ATOM 179 O OD1 . ASN A 1 21 ? -22.495 15.341 -1.627 1.00 42.77 ? 25 ASN A OD1 1 ATOM 180 N ND2 . ASN A 1 21 ? -23.144 17.011 -2.986 1.00 39.68 ? 25 ASN A ND2 1 ATOM 181 N N . GLY A 1 22 ? -26.717 18.711 -0.342 1.00 40.41 ? 26 GLY A N 1 ATOM 182 C CA . GLY A 1 22 ? -27.999 18.894 0.329 1.00 40.18 ? 26 GLY A CA 1 ATOM 183 C C . GLY A 1 22 ? -28.017 19.606 1.675 1.00 40.17 ? 26 GLY A C 1 ATOM 184 O O . GLY A 1 22 ? -28.639 19.111 2.613 1.00 40.48 ? 26 GLY A O 1 ATOM 185 N N . PRO A 1 23 ? -27.359 20.776 1.791 1.00 39.87 ? 27 PRO A N 1 ATOM 186 C CA . PRO A 1 23 ? -27.474 21.388 3.102 1.00 39.79 ? 27 PRO A CA 1 ATOM 187 C C . PRO A 1 23 ? -28.897 21.903 3.299 1.00 40.10 ? 27 PRO A C 1 ATOM 188 O O . PRO A 1 23 ? -29.574 22.223 2.312 1.00 40.00 ? 27 PRO A O 1 ATOM 189 C CB . PRO A 1 23 ? -26.467 22.531 3.040 1.00 39.82 ? 27 PRO A CB 1 ATOM 190 C CG . PRO A 1 23 ? -26.367 22.868 1.587 1.00 39.58 ? 27 PRO A CG 1 ATOM 191 C CD . PRO A 1 23 ? -26.548 21.587 0.862 1.00 39.66 ? 27 PRO A CD 1 ATOM 192 N N . MET A 1 24 ? -29.342 21.960 4.558 1.00 40.39 ? 28 MET A N 1 ATOM 193 C CA . MET A 1 24 ? -30.733 22.295 4.919 1.00 40.77 ? 28 MET A CA 1 ATOM 194 C C . MET A 1 24 ? -30.898 22.515 6.430 1.00 40.92 ? 28 MET A C 1 ATOM 195 O O . MET A 1 24 ? -29.978 22.274 7.205 1.00 40.72 ? 28 MET A O 1 ATOM 196 C CB . MET A 1 24 ? -31.677 21.171 4.477 1.00 40.42 ? 28 MET A CB 1 ATOM 197 C CG . MET A 1 24 ? -31.216 19.794 4.934 1.00 40.73 ? 28 MET A CG 1 ATOM 198 S SD . MET A 1 24 ? -32.318 18.436 4.508 1.00 41.26 ? 28 MET A SD 1 ATOM 199 C CE . MET A 1 24 ? -33.513 18.617 5.817 1.00 43.18 ? 28 MET A CE 1 ATOM 200 N N . ILE A 1 25 ? -32.076 22.983 6.833 1.00 41.37 ? 29 ILE A N 1 ATOM 201 C CA . ILE A 1 25 ? -32.486 22.957 8.235 1.00 41.97 ? 29 ILE A CA 1 ATOM 202 C C . ILE A 1 25 ? -33.828 22.236 8.351 1.00 42.68 ? 29 ILE A C 1 ATOM 203 O O . ILE A 1 25 ? -34.754 22.512 7.591 1.00 42.63 ? 29 ILE A O 1 ATOM 204 C CB . ILE A 1 25 ? -32.552 24.379 8.895 1.00 41.93 ? 29 ILE A CB 1 ATOM 205 C CG1 . ILE A 1 25 ? -32.833 24.261 10.400 1.00 41.47 ? 29 ILE A CG1 1 ATOM 206 C CG2 . ILE A 1 25 ? -33.588 25.280 8.217 1.00 41.00 ? 29 ILE A CG2 1 ATOM 207 C CD1 . ILE A 1 25 ? -32.296 25.423 11.230 1.00 40.79 ? 29 ILE A CD1 1 ATOM 208 N N . TYR A 1 26 ? -33.915 21.292 9.286 1.00 43.44 ? 30 TYR A N 1 ATOM 209 C CA . TYR A 1 26 ? -35.174 20.601 9.570 1.00 44.17 ? 30 TYR A CA 1 ATOM 210 C C . TYR A 1 26 ? -35.337 20.399 11.073 1.00 44.62 ? 30 TYR A C 1 ATOM 211 O O . TYR A 1 26 ? -34.439 19.888 11.746 1.00 44.63 ? 30 TYR A O 1 ATOM 212 C CB . TYR A 1 26 ? -35.237 19.271 8.822 1.00 44.36 ? 30 TYR A CB 1 ATOM 213 C CG . TYR A 1 26 ? -36.488 18.454 9.048 1.00 44.34 ? 30 TYR A CG 1 ATOM 214 C CD1 . TYR A 1 26 ? -37.717 18.853 8.515 1.00 44.72 ? 30 TYR A CD1 1 ATOM 215 C CD2 . TYR A 1 26 ? -36.435 17.264 9.761 1.00 43.82 ? 30 TYR A CD2 1 ATOM 216 C CE1 . TYR A 1 26 ? -38.871 18.090 8.709 1.00 44.02 ? 30 TYR A CE1 1 ATOM 217 C CE2 . TYR A 1 26 ? -37.571 16.496 9.957 1.00 44.45 ? 30 TYR A CE2 1 ATOM 218 C CZ . TYR A 1 26 ? -38.785 16.915 9.433 1.00 44.59 ? 30 TYR A CZ 1 ATOM 219 O OH . TYR A 1 26 ? -39.908 16.145 9.637 1.00 45.42 ? 30 TYR A OH 1 ATOM 220 N N . LYS A 1 27 ? -36.486 20.830 11.589 1.00 45.25 ? 31 LYS A N 1 ATOM 221 C CA . LYS A 1 27 ? -36.777 20.790 13.022 1.00 45.97 ? 31 LYS A CA 1 ATOM 222 C C . LYS A 1 27 ? -35.650 21.437 13.831 1.00 45.77 ? 31 LYS A C 1 ATOM 223 O O . LYS A 1 27 ? -35.144 20.851 14.797 1.00 46.09 ? 31 LYS A O 1 ATOM 224 C CB . LYS A 1 27 ? -37.063 19.347 13.482 1.00 46.03 ? 31 LYS A CB 1 ATOM 225 C CG . LYS A 1 27 ? -38.298 18.737 12.809 1.00 46.93 ? 31 LYS A CG 1 ATOM 226 C CD . LYS A 1 27 ? -38.578 17.322 13.271 1.00 47.02 ? 31 LYS A CD 1 ATOM 227 C CE . LYS A 1 27 ? -39.978 16.914 12.860 1.00 49.30 ? 31 LYS A CE 1 ATOM 228 N NZ . LYS A 1 27 ? -40.403 15.671 13.565 1.00 51.87 ? 31 LYS A NZ 1 ATOM 229 N N . GLY A 1 28 ? -35.259 22.643 13.413 1.00 45.47 ? 32 GLY A N 1 ATOM 230 C CA . GLY A 1 28 ? -34.194 23.407 14.064 1.00 44.95 ? 32 GLY A CA 1 ATOM 231 C C . GLY A 1 28 ? -32.848 22.708 14.109 1.00 44.64 ? 32 GLY A C 1 ATOM 232 O O . GLY A 1 28 ? -32.051 22.972 15.001 1.00 44.54 ? 32 GLY A O 1 ATOM 233 N N . ILE A 1 29 ? -32.605 21.812 13.149 1.00 44.64 ? 33 ILE A N 1 ATOM 234 C CA . ILE A 1 29 ? -31.332 21.072 13.029 1.00 44.38 ? 33 ILE A CA 1 ATOM 235 C C . ILE A 1 29 ? -30.674 21.225 11.645 1.00 43.98 ? 33 ILE A C 1 ATOM 236 O O . ILE A 1 29 ? -31.288 20.944 10.608 1.00 43.69 ? 33 ILE A O 1 ATOM 237 C CB . ILE A 1 29 ? -31.512 19.575 13.360 1.00 44.46 ? 33 ILE A CB 1 ATOM 238 C CG1 . ILE A 1 29 ? -31.698 19.386 14.869 1.00 44.57 ? 33 ILE A CG1 1 ATOM 239 C CG2 . ILE A 1 29 ? -30.311 18.754 12.862 1.00 44.94 ? 33 ILE A CG2 1 ATOM 240 C CD1 . ILE A 1 29 ? -32.800 18.403 15.230 1.00 44.61 ? 33 ILE A CD1 1 ATOM 241 N N . TYR A 1 30 ? -29.418 21.670 11.653 1.00 43.53 ? 34 TYR A N 1 ATOM 242 C CA . TYR A 1 30 ? -28.642 21.856 10.428 1.00 43.06 ? 34 TYR A CA 1 ATOM 243 C C . TYR A 1 30 ? -28.030 20.556 9.925 1.00 42.93 ? 34 TYR A C 1 ATOM 244 O O . TYR A 1 30 ? -27.381 19.825 10.683 1.00 42.98 ? 34 TYR A O 1 ATOM 245 C CB . TYR A 1 30 ? -27.532 22.882 10.638 1.00 42.65 ? 34 TYR A CB 1 ATOM 246 C CG . TYR A 1 30 ? -28.018 24.271 10.961 1.00 42.08 ? 34 TYR A CG 1 ATOM 247 C CD1 . TYR A 1 30 ? -28.459 25.117 9.956 1.00 41.59 ? 34 TYR A CD1 1 ATOM 248 C CD2 . TYR A 1 30 ? -28.009 24.751 12.276 1.00 41.68 ? 34 TYR A CD2 1 ATOM 249 C CE1 . TYR A 1 30 ? -28.891 26.401 10.243 1.00 42.31 ? 34 TYR A CE1 1 ATOM 250 C CE2 . TYR A 1 30 ? -28.440 26.035 12.577 1.00 40.78 ? 34 TYR A CE2 1 ATOM 251 C CZ . TYR A 1 30 ? -28.882 26.853 11.550 1.00 41.85 ? 34 TYR A CZ 1 ATOM 252 O OH . TYR A 1 30 ? -29.315 28.128 11.808 1.00 42.01 ? 34 TYR A OH 1 ATOM 253 N N . HIS A 1 31 ? -28.228 20.288 8.637 1.00 42.77 ? 35 HIS A N 1 ATOM 254 C CA . HIS A 1 31 ? -27.622 19.130 7.986 1.00 42.65 ? 35 HIS A CA 1 ATOM 255 C C . HIS A 1 31 ? -26.573 19.499 6.942 1.00 42.31 ? 35 HIS A C 1 ATOM 256 O O . HIS A 1 31 ? -26.724 20.472 6.199 1.00 42.48 ? 35 HIS A O 1 ATOM 257 C CB . HIS A 1 31 ? -28.697 18.272 7.340 1.00 42.67 ? 35 HIS A CB 1 ATOM 258 C CG . HIS A 1 31 ? -29.685 17.725 8.314 1.00 43.16 ? 35 HIS A CG 1 ATOM 259 N ND1 . HIS A 1 31 ? -29.683 16.407 8.712 1.00 42.86 ? 35 HIS A ND1 1 ATOM 260 C CD2 . HIS A 1 31 ? -30.700 18.322 8.984 1.00 43.65 ? 35 HIS A CD2 1 ATOM 261 C CE1 . HIS A 1 31 ? -30.664 16.212 9.575 1.00 43.82 ? 35 HIS A CE1 1 ATOM 262 N NE2 . HIS A 1 31 ? -31.292 17.360 9.761 1.00 44.05 ? 35 HIS A NE2 1 ATOM 263 N N . LEU A 1 32 ? -25.501 18.719 6.911 1.00 41.92 ? 36 LEU A N 1 ATOM 264 C CA . LEU A 1 32 ? -24.568 18.739 5.795 1.00 41.49 ? 36 LEU A CA 1 ATOM 265 C C . LEU A 1 32 ? -24.334 17.313 5.323 1.00 41.45 ? 36 LEU A C 1 ATOM 266 O O . LEU A 1 32 ? -23.997 16.428 6.109 1.00 41.36 ? 36 LEU A O 1 ATOM 267 C CB . LEU A 1 32 ? -23.242 19.400 6.179 1.00 41.40 ? 36 LEU A CB 1 ATOM 268 C CG . LEU A 1 32 ? -22.150 19.411 5.109 1.00 40.83 ? 36 LEU A CG 1 ATOM 269 C CD1 . LEU A 1 32 ? -22.400 20.495 4.099 1.00 41.03 ? 36 LEU A CD1 1 ATOM 270 C CD2 . LEU A 1 32 ? -20.811 19.623 5.754 1.00 41.21 ? 36 LEU A CD2 1 ATOM 271 N N . PHE A 1 33 ? -24.562 17.093 4.038 1.00 41.28 ? 37 PHE A N 1 ATOM 272 C CA . PHE A 1 33 ? -24.100 15.892 3.387 1.00 41.11 ? 37 PHE A CA 1 ATOM 273 C C . PHE A 1 33 ? -22.905 16.308 2.532 1.00 41.19 ? 37 PHE A C 1 ATOM 274 O O . PHE A 1 33 ? -22.696 17.498 2.278 1.00 41.23 ? 37 PHE A O 1 ATOM 275 C CB . PHE A 1 33 ? -25.198 15.280 2.523 1.00 40.83 ? 37 PHE A CB 1 ATOM 276 C CG . PHE A 1 33 ? -26.512 15.077 3.240 1.00 40.86 ? 37 PHE A CG 1 ATOM 277 C CD1 . PHE A 1 33 ? -26.852 13.829 3.764 1.00 40.30 ? 37 PHE A CD1 1 ATOM 278 C CD2 . PHE A 1 33 ? -27.429 16.128 3.363 1.00 39.62 ? 37 PHE A CD2 1 ATOM 279 C CE1 . PHE A 1 33 ? -28.074 13.639 4.405 1.00 39.49 ? 37 PHE A CE1 1 ATOM 280 C CE2 . PHE A 1 33 ? -28.646 15.945 4.006 1.00 38.30 ? 37 PHE A CE2 1 ATOM 281 C CZ . PHE A 1 33 ? -28.972 14.705 4.526 1.00 39.37 ? 37 PHE A CZ 1 ATOM 282 N N . TYR A 1 34 ? -22.108 15.339 2.104 1.00 41.06 ? 38 TYR A N 1 ATOM 283 C CA . TYR A 1 34 ? -20.946 15.645 1.302 1.00 40.84 ? 38 TYR A CA 1 ATOM 284 C C . TYR A 1 34 ? -20.385 14.454 0.561 1.00 41.16 ? 38 TYR A C 1 ATOM 285 O O . TYR A 1 34 ? -20.386 13.317 1.052 1.00 41.17 ? 38 TYR A O 1 ATOM 286 C CB . TYR A 1 34 ? -19.852 16.296 2.147 1.00 40.50 ? 38 TYR A CB 1 ATOM 287 C CG . TYR A 1 34 ? -19.385 15.492 3.335 1.00 40.43 ? 38 TYR A CG 1 ATOM 288 C CD1 . TYR A 1 34 ? -20.020 15.608 4.565 1.00 40.63 ? 38 TYR A CD1 1 ATOM 289 C CD2 . TYR A 1 34 ? -18.282 14.639 3.241 1.00 40.05 ? 38 TYR A CD2 1 ATOM 290 C CE1 . TYR A 1 34 ? -19.585 14.883 5.666 1.00 40.17 ? 38 TYR A CE1 1 ATOM 291 C CE2 . TYR A 1 34 ? -17.829 13.925 4.338 1.00 39.23 ? 38 TYR A CE2 1 ATOM 292 C CZ . TYR A 1 34 ? -18.487 14.054 5.552 1.00 39.94 ? 38 TYR A CZ 1 ATOM 293 O OH . TYR A 1 34 ? -18.073 13.340 6.654 1.00 39.73 ? 38 TYR A OH 1 ATOM 294 N N . GLN A 1 35 ? -19.893 14.743 -0.635 1.00 41.47 ? 39 GLN A N 1 ATOM 295 C CA . GLN A 1 35 ? -19.190 13.774 -1.447 1.00 41.89 ? 39 GLN A CA 1 ATOM 296 C C . GLN A 1 35 ? -18.007 13.184 -0.674 1.00 42.09 ? 39 GLN A C 1 ATOM 297 O O . GLN A 1 35 ? -17.044 13.882 -0.370 1.00 41.72 ? 39 GLN A O 1 ATOM 298 C CB . GLN A 1 35 ? -18.727 14.452 -2.735 1.00 41.80 ? 39 GLN A CB 1 ATOM 299 C CG . GLN A 1 35 ? -19.846 15.047 -3.564 1.00 41.56 ? 39 GLN A CG 1 ATOM 300 C CD . GLN A 1 35 ? -20.659 13.989 -4.271 1.00 42.22 ? 39 GLN A CD 1 ATOM 301 O OE1 . GLN A 1 35 ? -20.160 13.296 -5.151 1.00 43.20 ? 39 GLN A OE1 1 ATOM 302 N NE2 . GLN A 1 35 ? -21.919 13.857 -3.889 1.00 42.75 ? 39 GLN A NE2 1 ATOM 303 N N . TRP A 1 36 ? -18.097 11.900 -0.342 1.00 43.02 ? 40 TRP A N 1 ATOM 304 C CA . TRP A 1 36 ? -17.033 11.235 0.422 1.00 44.33 ? 40 TRP A CA 1 ATOM 305 C C . TRP A 1 36 ? -16.537 9.932 -0.207 1.00 45.14 ? 40 TRP A C 1 ATOM 306 O O . TRP A 1 36 ? -17.305 9.191 -0.823 1.00 45.23 ? 40 TRP A O 1 ATOM 307 C CB . TRP A 1 36 ? -17.499 10.976 1.853 1.00 44.39 ? 40 TRP A CB 1 ATOM 308 C CG . TRP A 1 36 ? -16.408 10.661 2.834 1.00 44.53 ? 40 TRP A CG 1 ATOM 309 C CD1 . TRP A 1 36 ? -15.337 11.442 3.143 1.00 44.75 ? 40 TRP A CD1 1 ATOM 310 C CD2 . TRP A 1 36 ? -16.307 9.496 3.668 1.00 45.32 ? 40 TRP A CD2 1 ATOM 311 N NE1 . TRP A 1 36 ? -14.564 10.836 4.101 1.00 44.56 ? 40 TRP A NE1 1 ATOM 312 C CE2 . TRP A 1 36 ? -15.138 9.642 4.446 1.00 45.02 ? 40 TRP A CE2 1 ATOM 313 C CE3 . TRP A 1 36 ? -17.092 8.341 3.831 1.00 45.70 ? 40 TRP A CE3 1 ATOM 314 C CZ2 . TRP A 1 36 ? -14.723 8.674 5.369 1.00 45.00 ? 40 TRP A CZ2 1 ATOM 315 C CZ3 . TRP A 1 36 ? -16.684 7.382 4.754 1.00 45.05 ? 40 TRP A CZ3 1 ATOM 316 C CH2 . TRP A 1 36 ? -15.506 7.554 5.508 1.00 44.99 ? 40 TRP A CH2 1 ATOM 317 N N . ASN A 1 37 ? -15.240 9.675 -0.055 1.00 46.25 ? 41 ASN A N 1 ATOM 318 C CA . ASN A 1 37 ? -14.634 8.393 -0.425 1.00 47.21 ? 41 ASN A CA 1 ATOM 319 C C . ASN A 1 37 ? -14.305 7.572 0.828 1.00 47.86 ? 41 ASN A C 1 ATOM 320 O O . ASN A 1 37 ? -13.278 7.808 1.481 1.00 47.82 ? 41 ASN A O 1 ATOM 321 C CB . ASN A 1 37 ? -13.369 8.603 -1.277 1.00 47.05 ? 41 ASN A CB 1 ATOM 322 C CG . ASN A 1 37 ? -12.705 7.290 -1.695 1.00 47.03 ? 41 ASN A CG 1 ATOM 323 O OD1 . ASN A 1 37 ? -12.922 6.235 -1.099 1.00 46.91 ? 41 ASN A OD1 1 ATOM 324 N ND2 . ASN A 1 37 ? -11.883 7.360 -2.728 1.00 47.82 ? 41 ASN A ND2 1 ATOM 325 N N . PRO A 1 38 ? -15.159 6.586 1.150 1.00 48.59 ? 42 PRO A N 1 ATOM 326 C CA . PRO A 1 38 ? -14.930 5.740 2.329 1.00 49.12 ? 42 PRO A CA 1 ATOM 327 C C . PRO A 1 38 ? -13.643 4.917 2.251 1.00 49.55 ? 42 PRO A C 1 ATOM 328 O O . PRO A 1 38 ? -13.089 4.569 3.290 1.00 49.59 ? 42 PRO A O 1 ATOM 329 C CB . PRO A 1 38 ? -16.159 4.827 2.363 1.00 48.99 ? 42 PRO A CB 1 ATOM 330 C CG . PRO A 1 38 ? -16.730 4.880 0.999 1.00 49.21 ? 42 PRO A CG 1 ATOM 331 C CD . PRO A 1 38 ? -16.376 6.204 0.415 1.00 48.60 ? 42 PRO A CD 1 ATOM 332 N N . LYS A 1 39 ? -13.161 4.636 1.040 1.00 50.17 ? 43 LYS A N 1 ATOM 333 C CA . LYS A 1 39 ? -11.963 3.801 0.865 1.00 50.81 ? 43 LYS A CA 1 ATOM 334 C C . LYS A 1 39 ? -10.626 4.573 0.851 1.00 50.81 ? 43 LYS A C 1 ATOM 335 O O . LYS A 1 39 ? -9.739 4.288 1.661 1.00 51.16 ? 43 LYS A O 1 ATOM 336 C CB . LYS A 1 39 ? -12.083 2.882 -0.365 1.00 50.95 ? 43 LYS A CB 1 ATOM 337 C CG . LYS A 1 39 ? -13.250 1.859 -0.345 1.00 52.13 ? 43 LYS A CG 1 ATOM 338 C CD . LYS A 1 39 ? -13.540 1.247 1.043 1.00 54.23 ? 43 LYS A CD 1 ATOM 339 C CE . LYS A 1 39 ? -12.444 0.283 1.537 1.00 55.88 ? 43 LYS A CE 1 ATOM 340 N NZ . LYS A 1 39 ? -12.213 -0.871 0.619 1.00 55.97 ? 43 LYS A NZ 1 ATOM 341 N N . GLY A 1 40 ? -10.480 5.542 -0.049 1.00 50.48 ? 44 GLY A N 1 ATOM 342 C CA . GLY A 1 40 ? -9.220 6.280 -0.160 1.00 49.89 ? 44 GLY A CA 1 ATOM 343 C C . GLY A 1 40 ? -9.281 7.785 0.060 1.00 49.58 ? 44 GLY A C 1 ATOM 344 O O . GLY A 1 40 ? -10.303 8.333 0.512 1.00 49.61 ? 44 GLY A O 1 ATOM 345 N N . ALA A 1 41 ? -8.168 8.448 -0.267 1.00 48.92 ? 45 ALA A N 1 ATOM 346 C CA . ALA A 1 41 ? -8.024 9.899 -0.130 1.00 48.17 ? 45 ALA A CA 1 ATOM 347 C C . ALA A 1 41 ? -7.863 10.597 -1.486 1.00 47.79 ? 45 ALA A C 1 ATOM 348 O O . ALA A 1 41 ? -7.333 11.706 -1.571 1.00 47.60 ? 45 ALA A O 1 ATOM 349 C CB . ALA A 1 41 ? -6.866 10.235 0.796 1.00 48.07 ? 45 ALA A CB 1 ATOM 350 N N . VAL A 1 42 ? -8.311 9.925 -2.544 1.00 47.34 ? 46 VAL A N 1 ATOM 351 C CA . VAL A 1 42 ? -8.511 10.553 -3.848 1.00 46.88 ? 46 VAL A CA 1 ATOM 352 C C . VAL A 1 42 ? -10.007 10.456 -4.151 1.00 46.77 ? 46 VAL A C 1 ATOM 353 O O . VAL A 1 42 ? -10.741 9.813 -3.404 1.00 47.00 ? 46 VAL A O 1 ATOM 354 C CB . VAL A 1 42 ? -7.642 9.901 -4.977 1.00 46.81 ? 46 VAL A CB 1 ATOM 355 C CG1 . VAL A 1 42 ? -6.167 10.143 -4.725 1.00 46.61 ? 46 VAL A CG1 1 ATOM 356 C CG2 . VAL A 1 42 ? -7.917 8.407 -5.122 1.00 46.40 ? 46 VAL A CG2 1 ATOM 357 N N . TRP A 1 43 ? -10.471 11.085 -5.225 1.00 46.41 ? 47 TRP A N 1 ATOM 358 C CA . TRP A 1 43 ? -11.866 10.919 -5.626 1.00 46.23 ? 47 TRP A CA 1 ATOM 359 C C . TRP A 1 43 ? -12.185 9.454 -5.993 1.00 46.18 ? 47 TRP A C 1 ATOM 360 O O . TRP A 1 43 ? -11.420 8.808 -6.712 1.00 46.21 ? 47 TRP A O 1 ATOM 361 C CB . TRP A 1 43 ? -12.192 11.844 -6.796 1.00 46.11 ? 47 TRP A CB 1 ATOM 362 C CG . TRP A 1 43 ? -13.655 11.980 -7.050 1.00 46.18 ? 47 TRP A CG 1 ATOM 363 C CD1 . TRP A 1 43 ? -14.488 12.921 -6.523 1.00 46.30 ? 47 TRP A CD1 1 ATOM 364 C CD2 . TRP A 1 43 ? -14.469 11.140 -7.882 1.00 46.73 ? 47 TRP A CD2 1 ATOM 365 N NE1 . TRP A 1 43 ? -15.771 12.727 -6.978 1.00 46.77 ? 47 TRP A NE1 1 ATOM 366 C CE2 . TRP A 1 43 ? -15.788 11.642 -7.815 1.00 46.71 ? 47 TRP A CE2 1 ATOM 367 C CE3 . TRP A 1 43 ? -14.212 10.014 -8.682 1.00 46.37 ? 47 TRP A CE3 1 ATOM 368 C CZ2 . TRP A 1 43 ? -16.850 11.057 -8.518 1.00 45.87 ? 47 TRP A CZ2 1 ATOM 369 C CZ3 . TRP A 1 43 ? -15.265 9.438 -9.379 1.00 45.80 ? 47 TRP A CZ3 1 ATOM 370 C CH2 . TRP A 1 43 ? -16.567 9.961 -9.290 1.00 45.82 ? 47 TRP A CH2 1 ATOM 371 N N . GLY A 1 44 ? -13.309 8.939 -5.499 1.00 45.99 ? 48 GLY A N 1 ATOM 372 C CA . GLY A 1 44 ? -13.749 7.587 -5.844 1.00 46.17 ? 48 GLY A CA 1 ATOM 373 C C . GLY A 1 44 ? -14.720 6.974 -4.847 1.00 46.44 ? 48 GLY A C 1 ATOM 374 O O . GLY A 1 44 ? -14.725 7.355 -3.673 1.00 46.71 ? 48 GLY A O 1 ATOM 375 N N . ASN A 1 45 ? -15.531 6.016 -5.320 1.00 46.37 ? 49 ASN A N 1 ATOM 376 C CA . ASN A 1 45 ? -16.565 5.330 -4.520 1.00 46.08 ? 49 ASN A CA 1 ATOM 377 C C . ASN A 1 45 ? -17.461 6.339 -3.826 1.00 46.14 ? 49 ASN A C 1 ATOM 378 O O . ASN A 1 45 ? -17.710 6.247 -2.619 1.00 46.27 ? 49 ASN A O 1 ATOM 379 C CB . ASN A 1 45 ? -15.958 4.384 -3.467 1.00 46.07 ? 49 ASN A CB 1 ATOM 380 C CG . ASN A 1 45 ? -14.672 3.729 -3.922 1.00 45.77 ? 49 ASN A CG 1 ATOM 381 O OD1 . ASN A 1 45 ? -13.648 3.837 -3.243 1.00 45.02 ? 49 ASN A OD1 1 ATOM 382 N ND2 . ASN A 1 45 ? -14.710 3.049 -5.072 1.00 45.03 ? 49 ASN A ND2 1 ATOM 383 N N . ILE A 1 46 ? -17.947 7.304 -4.592 1.00 46.10 ? 50 ILE A N 1 ATOM 384 C CA . ILE A 1 46 ? -18.492 8.505 -3.989 1.00 46.01 ? 50 ILE A CA 1 ATOM 385 C C . ILE A 1 46 ? -19.883 8.328 -3.367 1.00 45.69 ? 50 ILE A C 1 ATOM 386 O O . ILE A 1 46 ? -20.851 7.991 -4.056 1.00 46.09 ? 50 ILE A O 1 ATOM 387 C CB . ILE A 1 46 ? -18.363 9.726 -4.952 1.00 46.10 ? 50 ILE A CB 1 ATOM 388 C CG1 . ILE A 1 46 ? -17.857 10.951 -4.188 1.00 46.87 ? 50 ILE A CG1 1 ATOM 389 C CG2 . ILE A 1 46 ? -19.633 9.992 -5.746 1.00 46.24 ? 50 ILE A CG2 1 ATOM 390 C CD1 . ILE A 1 46 ? -16.371 10.830 -3.739 1.00 47.19 ? 50 ILE A CD1 1 ATOM 391 N N . VAL A 1 47 ? -19.943 8.523 -2.046 1.00 45.17 ? 51 VAL A N 1 ATOM 392 C CA . VAL A 1 47 ? -21.194 8.487 -1.263 1.00 44.26 ? 51 VAL A CA 1 ATOM 393 C C . VAL A 1 47 ? -21.476 9.820 -0.541 1.00 43.89 ? 51 VAL A C 1 ATOM 394 O O . VAL A 1 47 ? -20.585 10.666 -0.376 1.00 43.92 ? 51 VAL A O 1 ATOM 395 C CB . VAL A 1 47 ? -21.191 7.331 -0.217 1.00 44.26 ? 51 VAL A CB 1 ATOM 396 C CG1 . VAL A 1 47 ? -20.799 6.006 -0.871 1.00 43.79 ? 51 VAL A CG1 1 ATOM 397 C CG2 . VAL A 1 47 ? -20.276 7.658 0.976 1.00 43.46 ? 51 VAL A CG2 1 ATOM 398 N N . TRP A 1 48 ? -22.718 9.995 -0.107 1.00 43.34 ? 52 TRP A N 1 ATOM 399 C CA . TRP A 1 48 ? -23.115 11.164 0.685 1.00 42.77 ? 52 TRP A CA 1 ATOM 400 C C . TRP A 1 48 ? -22.881 10.937 2.183 1.00 42.66 ? 52 TRP A C 1 ATOM 401 O O . TRP A 1 48 ? -23.748 10.411 2.875 1.00 42.85 ? 52 TRP A O 1 ATOM 402 C CB . TRP A 1 48 ? -24.598 11.453 0.460 1.00 42.21 ? 52 TRP A CB 1 ATOM 403 C CG . TRP A 1 48 ? -24.916 12.166 -0.792 1.00 41.72 ? 52 TRP A CG 1 ATOM 404 C CD1 . TRP A 1 48 ? -24.377 11.951 -2.030 1.00 41.43 ? 52 TRP A CD1 1 ATOM 405 C CD2 . TRP A 1 48 ? -25.883 13.206 -0.947 1.00 41.76 ? 52 TRP A CD2 1 ATOM 406 N NE1 . TRP A 1 48 ? -24.942 12.804 -2.945 1.00 41.34 ? 52 TRP A NE1 1 ATOM 407 C CE2 . TRP A 1 48 ? -25.870 13.587 -2.305 1.00 41.81 ? 52 TRP A CE2 1 ATOM 408 C CE3 . TRP A 1 48 ? -26.759 13.859 -0.067 1.00 40.95 ? 52 TRP A CE3 1 ATOM 409 C CZ2 . TRP A 1 48 ? -26.697 14.600 -2.803 1.00 41.69 ? 52 TRP A CZ2 1 ATOM 410 C CZ3 . TRP A 1 48 ? -27.579 14.853 -0.561 1.00 41.11 ? 52 TRP A CZ3 1 ATOM 411 C CH2 . TRP A 1 48 ? -27.543 15.217 -1.917 1.00 41.33 ? 52 TRP A CH2 1 ATOM 412 N N . ALA A 1 49 ? -21.722 11.323 2.700 1.00 42.50 ? 53 ALA A N 1 ATOM 413 C CA . ALA A 1 49 ? -21.537 11.273 4.144 1.00 42.42 ? 53 ALA A CA 1 ATOM 414 C C . ALA A 1 49 ? -22.453 12.323 4.780 1.00 42.52 ? 53 ALA A C 1 ATOM 415 O O . ALA A 1 49 ? -22.975 13.197 4.088 1.00 42.61 ? 53 ALA A O 1 ATOM 416 C CB . ALA A 1 49 ? -20.100 11.489 4.512 1.00 42.27 ? 53 ALA A CB 1 ATOM 417 N N . HIS A 1 50 ? -22.669 12.226 6.086 1.00 42.57 ? 54 HIS A N 1 ATOM 418 C CA . HIS A 1 50 ? -23.743 12.975 6.722 1.00 42.38 ? 54 HIS A CA 1 ATOM 419 C C . HIS A 1 50 ? -23.359 13.397 8.124 1.00 42.53 ? 54 HIS A C 1 ATOM 420 O O . HIS A 1 50 ? -22.795 12.619 8.882 1.00 42.89 ? 54 HIS A O 1 ATOM 421 C CB . HIS A 1 50 ? -25.008 12.123 6.729 1.00 42.33 ? 54 HIS A CB 1 ATOM 422 C CG . HIS A 1 50 ? -26.232 12.828 7.225 1.00 42.38 ? 54 HIS A CG 1 ATOM 423 N ND1 . HIS A 1 50 ? -27.340 12.146 7.683 1.00 41.52 ? 54 HIS A ND1 1 ATOM 424 C CD2 . HIS A 1 50 ? -26.531 14.145 7.329 1.00 42.39 ? 54 HIS A CD2 1 ATOM 425 C CE1 . HIS A 1 50 ? -28.267 13.013 8.045 1.00 41.53 ? 54 HIS A CE1 1 ATOM 426 N NE2 . HIS A 1 50 ? -27.802 14.232 7.844 1.00 41.63 ? 54 HIS A NE2 1 ATOM 427 N N . SER A 1 51 ? -23.644 14.654 8.442 1.00 42.71 ? 55 SER A N 1 ATOM 428 C CA . SER A 1 51 ? -23.369 15.234 9.750 1.00 42.72 ? 55 SER A CA 1 ATOM 429 C C . SER A 1 51 ? -24.480 16.207 10.094 1.00 42.66 ? 55 SER A C 1 ATOM 430 O O . SER A 1 51 ? -25.173 16.701 9.200 1.00 42.59 ? 55 SER A O 1 ATOM 431 C CB . SER A 1 51 ? -22.026 15.963 9.754 1.00 42.57 ? 55 SER A CB 1 ATOM 432 O OG . SER A 1 51 ? -20.972 15.094 10.114 1.00 43.48 ? 55 SER A OG 1 ATOM 433 N N . THR A 1 52 ? -24.649 16.473 11.388 1.00 42.69 ? 56 THR A N 1 ATOM 434 C CA . THR A 1 52 ? -25.646 17.434 11.863 1.00 42.69 ? 56 THR A CA 1 ATOM 435 C C . THR A 1 52 ? -25.042 18.384 12.872 1.00 42.57 ? 56 THR A C 1 ATOM 436 O O . THR A 1 52 ? -24.002 18.093 13.468 1.00 42.48 ? 56 THR A O 1 ATOM 437 C CB . THR A 1 52 ? -26.847 16.748 12.536 1.00 42.75 ? 56 THR A CB 1 ATOM 438 O OG1 . THR A 1 52 ? -26.375 15.824 13.527 1.00 43.00 ? 56 THR A OG1 1 ATOM 439 C CG2 . THR A 1 52 ? -27.706 16.019 11.505 1.00 42.72 ? 56 THR A CG2 1 ATOM 440 N N . SER A 1 53 ? -25.716 19.513 13.065 1.00 42.54 ? 57 SER A N 1 ATOM 441 C CA . SER A 1 53 ? -25.257 20.548 13.987 1.00 42.67 ? 57 SER A CA 1 ATOM 442 C C . SER A 1 53 ? -26.414 21.406 14.473 1.00 42.72 ? 57 SER A C 1 ATOM 443 O O . SER A 1 53 ? -27.449 21.515 13.802 1.00 42.71 ? 57 SER A O 1 ATOM 444 C CB . SER A 1 53 ? -24.235 21.453 13.303 1.00 42.50 ? 57 SER A CB 1 ATOM 445 O OG . SER A 1 53 ? -23.860 22.516 14.155 1.00 42.48 ? 57 SER A OG 1 ATOM 446 N N . THR A 1 54 ? -26.227 22.027 15.634 1.00 42.58 ? 58 THR A N 1 ATOM 447 C CA . THR A 1 54 ? -27.186 23.014 16.122 1.00 42.66 ? 58 THR A CA 1 ATOM 448 C C . THR A 1 54 ? -26.665 24.446 15.914 1.00 42.32 ? 58 THR A C 1 ATOM 449 O O . THR A 1 54 ? -27.400 25.415 16.134 1.00 42.35 ? 58 THR A O 1 ATOM 450 C CB . THR A 1 54 ? -27.585 22.760 17.610 1.00 42.94 ? 58 THR A CB 1 ATOM 451 O OG1 . THR A 1 54 ? -26.482 23.057 18.487 1.00 43.40 ? 58 THR A OG1 1 ATOM 452 C CG2 . THR A 1 54 ? -28.025 21.299 17.802 1.00 43.01 ? 58 THR A CG2 1 ATOM 453 N N . ASP A 1 55 ? -25.413 24.570 15.461 1.00 41.73 ? 59 ASP A N 1 ATOM 454 C CA . ASP A 1 55 ? -24.752 25.870 15.366 1.00 41.16 ? 59 ASP A CA 1 ATOM 455 C C . ASP A 1 55 ? -23.889 26.101 14.102 1.00 40.82 ? 59 ASP A C 1 ATOM 456 O O . ASP A 1 55 ? -23.288 27.172 13.938 1.00 40.79 ? 59 ASP A O 1 ATOM 457 C CB . ASP A 1 55 ? -23.908 26.086 16.623 1.00 41.40 ? 59 ASP A CB 1 ATOM 458 C CG . ASP A 1 55 ? -22.789 25.060 16.765 1.00 41.63 ? 59 ASP A CG 1 ATOM 459 O OD1 . ASP A 1 55 ? -22.466 24.383 15.769 1.00 41.45 ? 59 ASP A OD1 1 ATOM 460 O OD2 . ASP A 1 55 ? -22.224 24.937 17.875 1.00 42.53 ? 59 ASP A OD2 1 ATOM 461 N N . LEU A 1 56 ? -23.815 25.103 13.223 1.00 40.03 ? 60 LEU A N 1 ATOM 462 C CA . LEU A 1 56 ? -23.014 25.185 11.980 1.00 39.25 ? 60 LEU A CA 1 ATOM 463 C C . LEU A 1 56 ? -21.489 25.111 12.187 1.00 38.85 ? 60 LEU A C 1 ATOM 464 O O . LEU A 1 56 ? -20.721 25.110 11.222 1.00 38.33 ? 60 LEU A O 1 ATOM 465 C CB . LEU A 1 56 ? -23.421 26.401 11.119 1.00 39.04 ? 60 LEU A CB 1 ATOM 466 C CG . LEU A 1 56 ? -24.815 26.317 10.477 1.00 38.78 ? 60 LEU A CG 1 ATOM 467 C CD1 . LEU A 1 56 ? -25.319 27.684 10.040 1.00 39.45 ? 60 LEU A CD1 1 ATOM 468 C CD2 . LEU A 1 56 ? -24.845 25.335 9.312 1.00 37.62 ? 60 LEU A CD2 1 ATOM 469 N N . ILE A 1 57 ? -21.066 25.036 13.448 1.00 38.75 ? 61 ILE A N 1 ATOM 470 C CA . ILE A 1 57 ? -19.647 24.955 13.794 1.00 38.68 ? 61 ILE A CA 1 ATOM 471 C C . ILE A 1 57 ? -19.253 23.577 14.333 1.00 39.02 ? 61 ILE A C 1 ATOM 472 O O . ILE A 1 57 ? -18.213 23.027 13.946 1.00 39.51 ? 61 ILE A O 1 ATOM 473 C CB . ILE A 1 57 ? -19.238 26.079 14.784 1.00 38.60 ? 61 ILE A CB 1 ATOM 474 C CG1 . ILE A 1 57 ? -19.522 27.466 14.182 1.00 38.39 ? 61 ILE A CG1 1 ATOM 475 C CG2 . ILE A 1 57 ? -17.778 25.952 15.203 1.00 37.82 ? 61 ILE A CG2 1 ATOM 476 C CD1 . ILE A 1 57 ? -19.043 27.673 12.743 1.00 37.21 ? 61 ILE A CD1 1 ATOM 477 N N . ASN A 1 58 ? -20.079 23.018 15.214 1.00 39.17 ? 62 ASN A N 1 ATOM 478 C CA . ASN A 1 58 ? -19.834 21.678 15.762 1.00 39.35 ? 62 ASN A CA 1 ATOM 479 C C . ASN A 1 58 ? -20.715 20.632 15.094 1.00 39.82 ? 62 ASN A C 1 ATOM 480 O O . ASN A 1 58 ? -21.930 20.831 14.974 1.00 40.12 ? 62 ASN A O 1 ATOM 481 C CB . ASN A 1 58 ? -20.053 21.673 17.269 1.00 39.17 ? 62 ASN A CB 1 ATOM 482 C CG . ASN A 1 58 ? -19.163 22.668 17.987 1.00 38.51 ? 62 ASN A CG 1 ATOM 483 O OD1 . ASN A 1 58 ? -17.960 22.457 18.116 1.00 36.98 ? 62 ASN A OD1 1 ATOM 484 N ND2 . ASN A 1 58 ? -19.754 23.767 18.452 1.00 37.21 ? 62 ASN A ND2 1 ATOM 485 N N . TRP A 1 59 ? -20.108 19.520 14.670 1.00 40.12 ? 63 TRP A N 1 ATOM 486 C CA . TRP A 1 59 ? -20.790 18.529 13.817 1.00 40.23 ? 63 TRP A CA 1 ATOM 487 C C . TRP A 1 59 ? -20.717 17.091 14.336 1.00 40.70 ? 63 TRP A C 1 ATOM 488 O O . TRP A 1 59 ? -19.638 16.598 14.673 1.00 40.88 ? 63 TRP A O 1 ATOM 489 C CB . TRP A 1 59 ? -20.249 18.605 12.379 1.00 39.92 ? 63 TRP A CB 1 ATOM 490 C CG . TRP A 1 59 ? -20.484 19.940 11.768 1.00 39.51 ? 63 TRP A CG 1 ATOM 491 C CD1 . TRP A 1 59 ? -19.674 21.042 11.860 1.00 39.08 ? 63 TRP A CD1 1 ATOM 492 C CD2 . TRP A 1 59 ? -21.623 20.338 11.005 1.00 38.76 ? 63 TRP A CD2 1 ATOM 493 N NE1 . TRP A 1 59 ? -20.241 22.097 11.195 1.00 39.42 ? 63 TRP A NE1 1 ATOM 494 C CE2 . TRP A 1 59 ? -21.440 21.695 10.662 1.00 39.13 ? 63 TRP A CE2 1 ATOM 495 C CE3 . TRP A 1 59 ? -22.784 19.680 10.577 1.00 38.11 ? 63 TRP A CE3 1 ATOM 496 C CZ2 . TRP A 1 59 ? -22.375 22.408 9.909 1.00 38.91 ? 63 TRP A CZ2 1 ATOM 497 C CZ3 . TRP A 1 59 ? -23.710 20.384 9.830 1.00 38.55 ? 63 TRP A CZ3 1 ATOM 498 C CH2 . TRP A 1 59 ? -23.502 21.735 9.503 1.00 39.14 ? 63 TRP A CH2 1 ATOM 499 N N . ASP A 1 60 ? -21.869 16.422 14.375 1.00 41.03 ? 64 ASP A N 1 ATOM 500 C CA . ASP A 1 60 ? -21.943 15.030 14.817 1.00 41.31 ? 64 ASP A CA 1 ATOM 501 C C . ASP A 1 60 ? -22.072 14.093 13.626 1.00 41.48 ? 64 ASP A C 1 ATOM 502 O O . ASP A 1 60 ? -22.877 14.348 12.725 1.00 41.61 ? 64 ASP A O 1 ATOM 503 C CB . ASP A 1 60 ? -23.124 14.816 15.770 1.00 41.44 ? 64 ASP A CB 1 ATOM 504 C CG . ASP A 1 60 ? -23.083 15.739 16.980 1.00 41.62 ? 64 ASP A CG 1 ATOM 505 O OD1 . ASP A 1 60 ? -22.089 15.702 17.755 1.00 41.42 ? 64 ASP A OD1 1 ATOM 506 O OD2 . ASP A 1 60 ? -24.065 16.498 17.145 1.00 41.07 ? 64 ASP A OD2 1 ATOM 507 N N . PRO A 1 61 ? -21.293 12.992 13.622 1.00 41.69 ? 65 PRO A N 1 ATOM 508 C CA . PRO A 1 61 ? -21.333 12.074 12.487 1.00 41.87 ? 65 PRO A CA 1 ATOM 509 C C . PRO A 1 61 ? -22.596 11.231 12.472 1.00 42.14 ? 65 PRO A C 1 ATOM 510 O O . PRO A 1 61 ? -23.294 11.116 13.484 1.00 42.29 ? 65 PRO A O 1 ATOM 511 C CB . PRO A 1 61 ? -20.108 11.186 12.707 1.00 41.55 ? 65 PRO A CB 1 ATOM 512 C CG . PRO A 1 61 ? -19.900 11.198 14.163 1.00 41.63 ? 65 PRO A CG 1 ATOM 513 C CD . PRO A 1 61 ? -20.344 12.538 14.658 1.00 41.82 ? 65 PRO A CD 1 ATOM 514 N N . HIS A 1 62 ? -22.872 10.660 11.310 1.00 42.36 ? 66 HIS A N 1 ATOM 515 C CA . HIS A 1 62 ? -23.981 9.754 11.093 1.00 42.56 ? 66 HIS A CA 1 ATOM 516 C C . HIS A 1 62 ? -23.550 8.908 9.899 1.00 42.48 ? 66 HIS A C 1 ATOM 517 O O . HIS A 1 62 ? -22.748 9.368 9.071 1.00 42.56 ? 66 HIS A O 1 ATOM 518 C CB . HIS A 1 62 ? -25.269 10.527 10.759 1.00 42.71 ? 66 HIS A CB 1 ATOM 519 C CG . HIS A 1 62 ? -25.752 11.428 11.857 1.00 43.91 ? 66 HIS A CG 1 ATOM 520 N ND1 . HIS A 1 62 ? -25.920 11.000 13.159 1.00 45.53 ? 66 HIS A ND1 1 ATOM 521 C CD2 . HIS A 1 62 ? -26.126 12.731 11.842 1.00 44.96 ? 66 HIS A CD2 1 ATOM 522 C CE1 . HIS A 1 62 ? -26.357 12.005 13.900 1.00 45.21 ? 66 HIS A CE1 1 ATOM 523 N NE2 . HIS A 1 62 ? -26.493 13.066 13.125 1.00 44.74 ? 66 HIS A NE2 1 ATOM 524 N N . PRO A 1 63 ? -24.074 7.673 9.793 1.00 42.40 ? 67 PRO A N 1 ATOM 525 C CA . PRO A 1 63 ? -23.742 6.810 8.646 1.00 42.10 ? 67 PRO A CA 1 ATOM 526 C C . PRO A 1 63 ? -24.113 7.459 7.297 1.00 41.90 ? 67 PRO A C 1 ATOM 527 O O . PRO A 1 63 ? -25.056 8.253 7.245 1.00 41.65 ? 67 PRO A O 1 ATOM 528 C CB . PRO A 1 63 ? -24.602 5.560 8.890 1.00 42.38 ? 67 PRO A CB 1 ATOM 529 C CG . PRO A 1 63 ? -25.671 5.989 9.886 1.00 42.18 ? 67 PRO A CG 1 ATOM 530 C CD . PRO A 1 63 ? -25.018 7.025 10.727 1.00 42.30 ? 67 PRO A CD 1 ATOM 531 N N . PRO A 1 64 ? -23.366 7.148 6.213 1.00 41.90 ? 68 PRO A N 1 ATOM 532 C CA . PRO A 1 64 ? -23.713 7.668 4.878 1.00 41.98 ? 68 PRO A CA 1 ATOM 533 C C . PRO A 1 64 ? -25.212 7.579 4.604 1.00 42.19 ? 68 PRO A C 1 ATOM 534 O O . PRO A 1 64 ? -25.819 6.567 4.922 1.00 42.81 ? 68 PRO A O 1 ATOM 535 C CB . PRO A 1 64 ? -22.959 6.728 3.934 1.00 41.81 ? 68 PRO A CB 1 ATOM 536 C CG . PRO A 1 64 ? -21.770 6.289 4.718 1.00 41.58 ? 68 PRO A CG 1 ATOM 537 C CD . PRO A 1 64 ? -22.148 6.312 6.177 1.00 41.71 ? 68 PRO A CD 1 ATOM 538 N N . ALA A 1 65 ? -25.805 8.622 4.033 1.00 42.40 ? 69 ALA A N 1 ATOM 539 C CA . ALA A 1 65 ? -27.245 8.632 3.775 1.00 42.70 ? 69 ALA A CA 1 ATOM 540 C C . ALA A 1 65 ? -27.636 8.124 2.383 1.00 43.25 ? 69 ALA A C 1 ATOM 541 O O . ALA A 1 65 ? -28.672 7.463 2.228 1.00 43.45 ? 69 ALA A O 1 ATOM 542 C CB . ALA A 1 65 ? -27.816 10.005 4.010 1.00 42.50 ? 69 ALA A CB 1 ATOM 543 N N . ILE A 1 66 ? -26.823 8.444 1.376 1.00 43.75 ? 70 ILE A N 1 ATOM 544 C CA . ILE A 1 66 ? -27.122 8.093 -0.021 1.00 43.96 ? 70 ILE A CA 1 ATOM 545 C C . ILE A 1 66 ? -25.888 7.481 -0.681 1.00 44.22 ? 70 ILE A C 1 ATOM 546 O O . ILE A 1 66 ? -24.871 8.155 -0.880 1.00 44.45 ? 70 ILE A O 1 ATOM 547 C CB . ILE A 1 66 ? -27.664 9.309 -0.836 1.00 43.71 ? 70 ILE A CB 1 ATOM 548 C CG1 . ILE A 1 66 ? -29.031 9.744 -0.304 1.00 43.98 ? 70 ILE A CG1 1 ATOM 549 C CG2 . ILE A 1 66 ? -27.821 8.948 -2.298 1.00 43.82 ? 70 ILE A CG2 1 ATOM 550 C CD1 . ILE A 1 66 ? -29.341 11.226 -0.488 1.00 44.31 ? 70 ILE A CD1 1 ATOM 551 N N . PHE A 1 67 ? -25.995 6.194 -1.002 1.00 44.40 ? 71 PHE A N 1 ATOM 552 C CA . PHE A 1 67 ? -24.909 5.410 -1.583 1.00 44.67 ? 71 PHE A CA 1 ATOM 553 C C . PHE A 1 67 ? -25.556 4.509 -2.629 1.00 45.05 ? 71 PHE A C 1 ATOM 554 O O . PHE A 1 67 ? -26.766 4.287 -2.552 1.00 45.56 ? 71 PHE A O 1 ATOM 555 C CB . PHE A 1 67 ? -24.198 4.583 -0.497 1.00 44.34 ? 71 PHE A CB 1 ATOM 556 C CG . PHE A 1 67 ? -25.141 3.942 0.488 1.00 44.68 ? 71 PHE A CG 1 ATOM 557 C CD1 . PHE A 1 67 ? -25.687 2.679 0.234 1.00 44.26 ? 71 PHE A CD1 1 ATOM 558 C CD2 . PHE A 1 67 ? -25.501 4.608 1.663 1.00 44.18 ? 71 PHE A CD2 1 ATOM 559 C CE1 . PHE A 1 67 ? -26.578 2.092 1.130 1.00 43.12 ? 71 PHE A CE1 1 ATOM 560 C CE2 . PHE A 1 67 ? -26.391 4.029 2.562 1.00 43.93 ? 71 PHE A CE2 1 ATOM 561 C CZ . PHE A 1 67 ? -26.935 2.767 2.290 1.00 43.79 ? 71 PHE A CZ 1 ATOM 562 N N . PRO A 1 68 ? -24.780 4.029 -3.633 1.00 45.26 ? 72 PRO A N 1 ATOM 563 C CA . PRO A 1 68 ? -25.262 3.104 -4.686 1.00 45.33 ? 72 PRO A CA 1 ATOM 564 C C . PRO A 1 68 ? -26.037 1.857 -4.207 1.00 45.35 ? 72 PRO A C 1 ATOM 565 O O . PRO A 1 68 ? -25.519 1.069 -3.414 1.00 45.23 ? 72 PRO A O 1 ATOM 566 C CB . PRO A 1 68 ? -23.967 2.693 -5.409 1.00 45.48 ? 72 PRO A CB 1 ATOM 567 C CG . PRO A 1 68 ? -22.838 3.217 -4.566 1.00 44.97 ? 72 PRO A CG 1 ATOM 568 C CD . PRO A 1 68 ? -23.371 4.399 -3.863 1.00 45.04 ? 72 PRO A CD 1 ATOM 569 N N . SER A 1 69 ? -27.265 1.691 -4.705 1.00 45.50 ? 73 SER A N 1 ATOM 570 C CA . SER A 1 69 ? -28.165 0.606 -4.276 1.00 45.73 ? 73 SER A CA 1 ATOM 571 C C . SER A 1 69 ? -29.171 0.149 -5.334 1.00 45.80 ? 73 SER A C 1 ATOM 572 O O . SER A 1 69 ? -29.865 -0.855 -5.141 1.00 45.92 ? 73 SER A O 1 ATOM 573 C CB . SER A 1 69 ? -28.969 1.047 -3.064 1.00 45.55 ? 73 SER A CB 1 ATOM 574 O OG . SER A 1 69 ? -28.109 1.475 -2.043 1.00 46.22 ? 73 SER A OG 1 ATOM 575 N N . ALA A 1 70 ? -29.267 0.892 -6.431 1.00 45.59 ? 74 ALA A N 1 ATOM 576 C CA . ALA A 1 70 ? -30.296 0.655 -7.431 1.00 45.57 ? 74 ALA A CA 1 ATOM 577 C C . ALA A 1 70 ? -29.796 0.978 -8.840 1.00 45.59 ? 74 ALA A C 1 ATOM 578 O O . ALA A 1 70 ? -28.725 1.556 -8.996 1.00 45.57 ? 74 ALA A O 1 ATOM 579 C CB . ALA A 1 70 ? -31.537 1.474 -7.093 1.00 45.79 ? 74 ALA A CB 1 ATOM 580 N N . PRO A 1 71 ? -30.558 0.583 -9.880 1.00 45.73 ? 75 PRO A N 1 ATOM 581 C CA . PRO A 1 71 ? -30.106 0.877 -11.235 1.00 45.79 ? 75 PRO A CA 1 ATOM 582 C C . PRO A 1 71 ? -29.759 2.345 -11.433 1.00 45.89 ? 75 PRO A C 1 ATOM 583 O O . PRO A 1 71 ? -28.764 2.652 -12.075 1.00 46.00 ? 75 PRO A O 1 ATOM 584 C CB . PRO A 1 71 ? -31.311 0.488 -12.093 1.00 45.79 ? 75 PRO A CB 1 ATOM 585 C CG . PRO A 1 71 ? -31.964 -0.587 -11.319 1.00 45.57 ? 75 PRO A CG 1 ATOM 586 C CD . PRO A 1 71 ? -31.827 -0.172 -9.887 1.00 45.57 ? 75 PRO A CD 1 ATOM 587 N N . PHE A 1 72 ? -30.551 3.234 -10.849 1.00 46.07 ? 76 PHE A N 1 ATOM 588 C CA . PHE A 1 72 ? -30.394 4.676 -11.059 1.00 46.32 ? 76 PHE A CA 1 ATOM 589 C C . PHE A 1 72 ? -29.197 5.368 -10.354 1.00 46.29 ? 76 PHE A C 1 ATOM 590 O O . PHE A 1 72 ? -28.932 6.544 -10.613 1.00 46.25 ? 76 PHE A O 1 ATOM 591 C CB . PHE A 1 72 ? -31.709 5.403 -10.745 1.00 46.54 ? 76 PHE A CB 1 ATOM 592 C CG . PHE A 1 72 ? -32.306 5.035 -9.421 1.00 46.48 ? 76 PHE A CG 1 ATOM 593 C CD1 . PHE A 1 72 ? -31.809 5.572 -8.245 1.00 47.21 ? 76 PHE A CD1 1 ATOM 594 C CD2 . PHE A 1 72 ? -33.374 4.155 -9.353 1.00 47.14 ? 76 PHE A CD2 1 ATOM 595 C CE1 . PHE A 1 72 ? -32.369 5.237 -7.011 1.00 48.57 ? 76 PHE A CE1 1 ATOM 596 C CE2 . PHE A 1 72 ? -33.942 3.813 -8.132 1.00 47.80 ? 76 PHE A CE2 1 ATOM 597 C CZ . PHE A 1 72 ? -33.438 4.356 -6.956 1.00 48.02 ? 76 PHE A CZ 1 ATOM 598 N N . ASP A 1 73 ? -28.483 4.659 -9.478 1.00 46.14 ? 77 ASP A N 1 ATOM 599 C CA . ASP A 1 73 ? -27.275 5.224 -8.863 1.00 46.07 ? 77 ASP A CA 1 ATOM 600 C C . ASP A 1 73 ? -26.157 4.212 -8.555 1.00 46.04 ? 77 ASP A C 1 ATOM 601 O O . ASP A 1 73 ? -25.247 4.500 -7.758 1.00 46.23 ? 77 ASP A O 1 ATOM 602 C CB . ASP A 1 73 ? -27.621 6.089 -7.629 1.00 46.09 ? 77 ASP A CB 1 ATOM 603 C CG . ASP A 1 73 ? -28.068 5.276 -6.422 1.00 46.25 ? 77 ASP A CG 1 ATOM 604 O OD1 . ASP A 1 73 ? -28.079 4.029 -6.477 1.00 46.04 ? 77 ASP A OD1 1 ATOM 605 O OD2 . ASP A 1 73 ? -28.411 5.902 -5.396 1.00 46.95 ? 77 ASP A OD2 1 ATOM 606 N N . ILE A 1 74 ? -26.219 3.050 -9.205 1.00 45.65 ? 78 ILE A N 1 ATOM 607 C CA . ILE A 1 74 ? -25.288 1.937 -8.952 1.00 45.34 ? 78 ILE A CA 1 ATOM 608 C C . ILE A 1 74 ? -23.806 2.316 -9.107 1.00 45.09 ? 78 ILE A C 1 ATOM 609 O O . ILE A 1 74 ? -22.944 1.781 -8.403 1.00 44.72 ? 78 ILE A O 1 ATOM 610 C CB . ILE A 1 74 ? -25.639 0.668 -9.819 1.00 45.35 ? 78 ILE A CB 1 ATOM 611 C CG1 . ILE A 1 74 ? -24.871 -0.570 -9.344 1.00 44.99 ? 78 ILE A CG1 1 ATOM 612 C CG2 . ILE A 1 74 ? -25.392 0.909 -11.321 1.00 45.50 ? 78 ILE A CG2 1 ATOM 613 C CD1 . ILE A 1 74 ? -25.269 -1.050 -7.962 1.00 45.43 ? 78 ILE A CD1 1 ATOM 614 N N . ASN A 1 75 ? -23.523 3.240 -10.020 1.00 44.84 ? 79 ASN A N 1 ATOM 615 C CA . ASN A 1 75 ? -22.147 3.629 -10.298 1.00 45.11 ? 79 ASN A CA 1 ATOM 616 C C . ASN A 1 75 ? -21.693 4.905 -9.578 1.00 44.93 ? 79 ASN A C 1 ATOM 617 O O . ASN A 1 75 ? -20.564 5.364 -9.773 1.00 45.12 ? 79 ASN A O 1 ATOM 618 C CB . ASN A 1 75 ? -21.904 3.741 -11.808 1.00 45.23 ? 79 ASN A CB 1 ATOM 619 C CG . ASN A 1 75 ? -22.015 2.408 -12.520 1.00 46.10 ? 79 ASN A CG 1 ATOM 620 O OD1 . ASN A 1 75 ? -21.485 1.390 -12.054 1.00 47.02 ? 79 ASN A OD1 1 ATOM 621 N ND2 . ASN A 1 75 ? -22.705 2.405 -13.664 1.00 46.41 ? 79 ASN A ND2 1 ATOM 622 N N . GLY A 1 76 ? -22.562 5.470 -8.746 1.00 44.62 ? 80 GLY A N 1 ATOM 623 C CA . GLY A 1 76 ? -22.183 6.627 -7.944 1.00 44.34 ? 80 GLY A CA 1 ATOM 624 C C . GLY A 1 76 ? -23.323 7.540 -7.546 1.00 44.09 ? 80 GLY A C 1 ATOM 625 O O . GLY A 1 76 ? -24.385 7.552 -8.192 1.00 44.12 ? 80 GLY A O 1 ATOM 626 N N . CYS A 1 77 ? -23.084 8.307 -6.479 1.00 43.47 ? 81 CYS A N 1 ATOM 627 C CA . CYS A 1 77 ? -24.058 9.247 -5.945 1.00 43.12 ? 81 CYS A CA 1 ATOM 628 C C . CYS A 1 77 ? -23.470 10.653 -5.868 1.00 42.76 ? 81 CYS A C 1 ATOM 629 O O . CYS A 1 77 ? -22.929 11.072 -4.831 1.00 42.63 ? 81 CYS A O 1 ATOM 630 C CB . CYS A 1 77 ? -24.547 8.783 -4.577 1.00 43.23 ? 81 CYS A CB 1 ATOM 631 S SG . CYS A 1 77 ? -25.479 7.256 -4.643 1.00 44.10 ? 81 CYS A SG 1 ATOM 632 N N . TRP A 1 78 ? -23.599 11.375 -6.980 1.00 42.14 ? 82 TRP A N 1 ATOM 633 C CA . TRP A 1 78 ? -22.989 12.698 -7.149 1.00 41.65 ? 82 TRP A CA 1 ATOM 634 C C . TRP A 1 78 ? -23.801 13.814 -6.477 1.00 41.43 ? 82 TRP A C 1 ATOM 635 O O . TRP A 1 78 ? -24.706 13.539 -5.687 1.00 41.17 ? 82 TRP A O 1 ATOM 636 C CB . TRP A 1 78 ? -22.765 12.972 -8.640 1.00 41.22 ? 82 TRP A CB 1 ATOM 637 C CG . TRP A 1 78 ? -21.734 12.078 -9.250 1.00 41.03 ? 82 TRP A CG 1 ATOM 638 C CD1 . TRP A 1 78 ? -21.232 10.918 -8.719 1.00 40.88 ? 82 TRP A CD1 1 ATOM 639 C CD2 . TRP A 1 78 ? -21.088 12.246 -10.518 1.00 40.93 ? 82 TRP A CD2 1 ATOM 640 N NE1 . TRP A 1 78 ? -20.306 10.367 -9.566 1.00 40.77 ? 82 TRP A NE1 1 ATOM 641 C CE2 . TRP A 1 78 ? -20.199 11.156 -10.682 1.00 40.70 ? 82 TRP A CE2 1 ATOM 642 C CE3 . TRP A 1 78 ? -21.172 13.211 -11.531 1.00 40.34 ? 82 TRP A CE3 1 ATOM 643 C CZ2 . TRP A 1 78 ? -19.396 11.006 -11.815 1.00 40.21 ? 82 TRP A CZ2 1 ATOM 644 C CZ3 . TRP A 1 78 ? -20.373 13.063 -12.658 1.00 40.91 ? 82 TRP A CZ3 1 ATOM 645 C CH2 . TRP A 1 78 ? -19.495 11.965 -12.791 1.00 40.79 ? 82 TRP A CH2 1 ATOM 646 N N . SER A 1 79 ? -23.473 15.066 -6.785 1.00 41.28 ? 83 SER A N 1 ATOM 647 C CA . SER A 1 79 ? -24.068 16.209 -6.082 1.00 41.27 ? 83 SER A CA 1 ATOM 648 C C . SER A 1 79 ? -25.575 16.329 -6.219 1.00 40.99 ? 83 SER A C 1 ATOM 649 O O . SER A 1 79 ? -26.189 15.686 -7.067 1.00 40.88 ? 83 SER A O 1 ATOM 650 C CB . SER A 1 79 ? -23.410 17.521 -6.500 1.00 41.08 ? 83 SER A CB 1 ATOM 651 O OG . SER A 1 79 ? -22.132 17.615 -5.922 1.00 41.60 ? 83 SER A OG 1 ATOM 652 N N . GLY A 1 80 ? -26.145 17.174 -5.368 1.00 40.81 ? 84 GLY A N 1 ATOM 653 C CA . GLY A 1 80 ? -27.578 17.370 -5.299 1.00 40.88 ? 84 GLY A CA 1 ATOM 654 C C . GLY A 1 80 ? -27.939 18.306 -4.168 1.00 40.90 ? 84 GLY A C 1 ATOM 655 O O . GLY A 1 80 ? -27.069 18.781 -3.435 1.00 41.13 ? 84 GLY A O 1 ATOM 656 N N . SER A 1 81 ? -29.230 18.568 -4.022 1.00 40.86 ? 85 SER A N 1 ATOM 657 C CA . SER A 1 81 ? -29.693 19.595 -3.107 1.00 40.97 ? 85 SER A CA 1 ATOM 658 C C . SER A 1 81 ? -30.940 19.141 -2.382 1.00 41.29 ? 85 SER A C 1 ATOM 659 O O . SER A 1 81 ? -31.669 18.287 -2.871 1.00 41.52 ? 85 SER A O 1 ATOM 660 C CB . SER A 1 81 ? -30.014 20.868 -3.885 1.00 40.92 ? 85 SER A CB 1 ATOM 661 O OG . SER A 1 81 ? -29.006 21.161 -4.833 1.00 40.13 ? 85 SER A OG 1 ATOM 662 N N . ALA A 1 82 ? -31.191 19.719 -1.217 1.00 41.59 ? 86 ALA A N 1 ATOM 663 C CA . ALA A 1 82 ? -32.430 19.458 -0.512 1.00 41.99 ? 86 ALA A CA 1 ATOM 664 C C . ALA A 1 82 ? -33.401 20.611 -0.730 1.00 42.42 ? 86 ALA A C 1 ATOM 665 O O . ALA A 1 82 ? -33.008 21.780 -0.723 1.00 42.46 ? 86 ALA A O 1 ATOM 666 C CB . ALA A 1 82 ? -32.169 19.243 0.953 1.00 41.86 ? 86 ALA A CB 1 ATOM 667 N N . THR A 1 83 ? -34.663 20.269 -0.961 1.00 42.83 ? 87 THR A N 1 ATOM 668 C CA . THR A 1 83 ? -35.736 21.244 -1.044 1.00 43.43 ? 87 THR A CA 1 ATOM 669 C C . THR A 1 83 ? -36.662 20.959 0.114 1.00 43.87 ? 87 THR A C 1 ATOM 670 O O . THR A 1 83 ? -36.911 19.799 0.422 1.00 44.16 ? 87 THR A O 1 ATOM 671 C CB . THR A 1 83 ? -36.542 21.104 -2.354 1.00 43.42 ? 87 THR A CB 1 ATOM 672 O OG1 . THR A 1 83 ? -35.670 21.214 -3.488 1.00 43.97 ? 87 THR A OG1 1 ATOM 673 C CG2 . THR A 1 83 ? -37.614 22.180 -2.449 1.00 43.44 ? 87 THR A CG2 1 ATOM 674 N N . ILE A 1 84 ? -37.173 22.005 0.756 1.00 44.56 ? 88 ILE A N 1 ATOM 675 C CA . ILE A 1 84 ? -38.170 21.825 1.808 1.00 45.39 ? 88 ILE A CA 1 ATOM 676 C C . ILE A 1 84 ? -39.587 22.063 1.274 1.00 46.02 ? 88 ILE A C 1 ATOM 677 O O . ILE A 1 84 ? -39.973 23.205 1.007 1.00 46.16 ? 88 ILE A O 1 ATOM 678 C CB . ILE A 1 84 ? -37.894 22.735 3.020 1.00 45.32 ? 88 ILE A CB 1 ATOM 679 C CG1 . ILE A 1 84 ? -36.432 22.604 3.487 1.00 45.76 ? 88 ILE A CG1 1 ATOM 680 C CG2 . ILE A 1 84 ? -38.885 22.452 4.150 1.00 45.38 ? 88 ILE A CG2 1 ATOM 681 C CD1 . ILE A 1 84 ? -36.017 21.214 3.972 1.00 45.62 ? 88 ILE A CD1 1 ATOM 682 N N . LEU A 1 85 ? -40.352 20.981 1.116 1.00 46.67 ? 89 LEU A N 1 ATOM 683 C CA . LEU A 1 85 ? -41.730 21.061 0.616 1.00 47.57 ? 89 LEU A CA 1 ATOM 684 C C . LEU A 1 85 ? -42.622 21.872 1.575 1.00 48.23 ? 89 LEU A C 1 ATOM 685 O O . LEU A 1 85 ? -42.383 21.865 2.788 1.00 48.48 ? 89 LEU A O 1 ATOM 686 C CB . LEU A 1 85 ? -42.300 19.661 0.365 1.00 47.47 ? 89 LEU A CB 1 ATOM 687 C CG . LEU A 1 85 ? -41.491 18.779 -0.590 1.00 47.87 ? 89 LEU A CG 1 ATOM 688 C CD1 . LEU A 1 85 ? -42.251 17.509 -0.939 1.00 48.17 ? 89 LEU A CD1 1 ATOM 689 C CD2 . LEU A 1 85 ? -41.131 19.531 -1.862 1.00 48.43 ? 89 LEU A CD2 1 ATOM 690 N N . PRO A 1 86 ? -43.650 22.572 1.042 1.00 48.68 ? 90 PRO A N 1 ATOM 691 C CA . PRO A 1 86 ? -44.320 23.599 1.850 1.00 48.95 ? 90 PRO A CA 1 ATOM 692 C C . PRO A 1 86 ? -44.956 23.059 3.130 1.00 49.36 ? 90 PRO A C 1 ATOM 693 O O . PRO A 1 86 ? -45.300 23.846 4.016 1.00 49.61 ? 90 PRO A O 1 ATOM 694 C CB . PRO A 1 86 ? -45.392 24.157 0.908 1.00 49.14 ? 90 PRO A CB 1 ATOM 695 C CG . PRO A 1 86 ? -44.967 23.755 -0.457 1.00 49.06 ? 90 PRO A CG 1 ATOM 696 C CD . PRO A 1 86 ? -44.259 22.449 -0.295 1.00 48.73 ? 90 PRO A CD 1 ATOM 697 N N . ASN A 1 87 ? -45.093 21.734 3.225 1.00 49.51 ? 91 ASN A N 1 ATOM 698 C CA . ASN A 1 87 ? -45.574 21.071 4.445 1.00 49.51 ? 91 ASN A CA 1 ATOM 699 C C . ASN A 1 87 ? -44.444 20.754 5.439 1.00 49.26 ? 91 ASN A C 1 ATOM 700 O O . ASN A 1 87 ? -44.640 20.003 6.400 1.00 49.55 ? 91 ASN A O 1 ATOM 701 C CB . ASN A 1 87 ? -46.368 19.796 4.100 1.00 49.50 ? 91 ASN A CB 1 ATOM 702 C CG . ASN A 1 87 ? -45.507 18.717 3.451 1.00 50.01 ? 91 ASN A CG 1 ATOM 703 O OD1 . ASN A 1 87 ? -44.377 18.964 3.029 1.00 51.06 ? 91 ASN A OD1 1 ATOM 704 N ND2 . ASN A 1 87 ? -46.048 17.514 3.365 1.00 50.67 ? 91 ASN A ND2 1 ATOM 705 N N . GLY A 1 88 ? -43.262 21.319 5.200 1.00 48.75 ? 92 GLY A N 1 ATOM 706 C CA . GLY A 1 88 ? -42.116 21.117 6.088 1.00 48.20 ? 92 GLY A CA 1 ATOM 707 C C . GLY A 1 88 ? -41.233 19.934 5.726 1.00 47.73 ? 92 GLY A C 1 ATOM 708 O O . GLY A 1 88 ? -40.077 19.870 6.161 1.00 47.67 ? 92 GLY A O 1 ATOM 709 N N . LYS A 1 89 ? -41.776 19.006 4.932 1.00 47.32 ? 93 LYS A N 1 ATOM 710 C CA . LYS A 1 89 ? -41.068 17.784 4.509 1.00 46.92 ? 93 LYS A CA 1 ATOM 711 C C . LYS A 1 89 ? -39.888 18.068 3.575 1.00 46.19 ? 93 LYS A C 1 ATOM 712 O O . LYS A 1 89 ? -40.057 18.720 2.545 1.00 46.06 ? 93 LYS A O 1 ATOM 713 C CB . LYS A 1 89 ? -42.033 16.793 3.840 1.00 46.98 ? 93 LYS A CB 1 ATOM 714 C CG . LYS A 1 89 ? -41.367 15.485 3.402 1.00 47.33 ? 93 LYS A CG 1 ATOM 715 C CD . LYS A 1 89 ? -42.286 14.641 2.541 1.00 47.35 ? 93 LYS A CD 1 ATOM 716 C CE . LYS A 1 89 ? -41.597 13.353 2.141 1.00 48.86 ? 93 LYS A CE 1 ATOM 717 N NZ . LYS A 1 89 ? -42.492 12.473 1.342 1.00 49.75 ? 93 LYS A NZ 1 ATOM 718 N N . PRO A 1 90 ? -38.689 17.582 3.944 1.00 45.68 ? 94 PRO A N 1 ATOM 719 C CA . PRO A 1 90 ? -37.468 17.762 3.153 1.00 45.22 ? 94 PRO A CA 1 ATOM 720 C C . PRO A 1 90 ? -37.256 16.662 2.132 1.00 44.80 ? 94 PRO A C 1 ATOM 721 O O . PRO A 1 90 ? -37.397 15.489 2.475 1.00 45.14 ? 94 PRO A O 1 ATOM 722 C CB . PRO A 1 90 ? -36.361 17.675 4.204 1.00 45.32 ? 94 PRO A CB 1 ATOM 723 C CG . PRO A 1 90 ? -36.944 16.906 5.360 1.00 45.20 ? 94 PRO A CG 1 ATOM 724 C CD . PRO A 1 90 ? -38.437 16.848 5.200 1.00 45.47 ? 94 PRO A CD 1 ATOM 725 N N . VAL A 1 91 ? -36.911 17.028 0.898 1.00 44.09 ? 95 VAL A N 1 ATOM 726 C CA . VAL A 1 91 ? -36.513 16.032 -0.112 1.00 43.64 ? 95 VAL A CA 1 ATOM 727 C C . VAL A 1 91 ? -35.190 16.371 -0.807 1.00 43.21 ? 95 VAL A C 1 ATOM 728 O O . VAL A 1 91 ? -34.822 17.536 -0.929 1.00 43.15 ? 95 VAL A O 1 ATOM 729 C CB . VAL A 1 91 ? -37.609 15.776 -1.175 1.00 43.80 ? 95 VAL A CB 1 ATOM 730 C CG1 . VAL A 1 91 ? -38.763 14.976 -0.582 1.00 43.71 ? 95 VAL A CG1 1 ATOM 731 C CG2 . VAL A 1 91 ? -38.095 17.088 -1.799 1.00 43.99 ? 95 VAL A CG2 1 ATOM 732 N N . ILE A 1 92 ? -34.480 15.343 -1.255 1.00 42.62 ? 96 ILE A N 1 ATOM 733 C CA . ILE A 1 92 ? -33.215 15.533 -1.944 1.00 42.08 ? 96 ILE A CA 1 ATOM 734 C C . ILE A 1 92 ? -33.283 15.103 -3.407 1.00 41.92 ? 96 ILE A C 1 ATOM 735 O O . ILE A 1 92 ? -33.652 13.968 -3.722 1.00 41.98 ? 96 ILE A O 1 ATOM 736 C CB . ILE A 1 92 ? -32.082 14.766 -1.254 1.00 42.10 ? 96 ILE A CB 1 ATOM 737 C CG1 . ILE A 1 92 ? -31.760 15.410 0.096 1.00 42.17 ? 96 ILE A CG1 1 ATOM 738 C CG2 . ILE A 1 92 ? -30.842 14.708 -2.160 1.00 41.93 ? 96 ILE A CG2 1 ATOM 739 C CD1 . ILE A 1 92 ? -30.776 14.613 0.960 1.00 42.07 ? 96 ILE A CD1 1 ATOM 740 N N . LEU A 1 93 ? -32.928 16.025 -4.293 1.00 41.62 ? 97 LEU A N 1 ATOM 741 C CA . LEU A 1 93 ? -32.675 15.699 -5.686 1.00 41.41 ? 97 LEU A CA 1 ATOM 742 C C . LEU A 1 93 ? -31.171 15.558 -5.881 1.00 41.50 ? 97 LEU A C 1 ATOM 743 O O . LEU A 1 93 ? -30.399 16.437 -5.478 1.00 41.29 ? 97 LEU A O 1 ATOM 744 C CB . LEU A 1 93 ? -33.243 16.774 -6.606 1.00 41.16 ? 97 LEU A CB 1 ATOM 745 C CG . LEU A 1 93 ? -34.749 16.705 -6.838 1.00 40.89 ? 97 LEU A CG 1 ATOM 746 C CD1 . LEU A 1 93 ? -35.218 17.940 -7.575 1.00 39.42 ? 97 LEU A CD1 1 ATOM 747 C CD2 . LEU A 1 93 ? -35.110 15.428 -7.605 1.00 41.05 ? 97 LEU A CD2 1 ATOM 748 N N . TYR A 1 94 ? -30.763 14.441 -6.480 1.00 41.52 ? 98 TYR A N 1 ATOM 749 C CA . TYR A 1 94 ? -29.350 14.146 -6.688 1.00 41.69 ? 98 TYR A CA 1 ATOM 750 C C . TYR A 1 94 ? -29.122 13.409 -8.001 1.00 42.06 ? 98 TYR A C 1 ATOM 751 O O . TYR A 1 94 ? -30.035 12.783 -8.542 1.00 42.20 ? 98 TYR A O 1 ATOM 752 C CB . TYR A 1 94 ? -28.781 13.345 -5.512 1.00 41.43 ? 98 TYR A CB 1 ATOM 753 C CG . TYR A 1 94 ? -29.152 11.879 -5.491 1.00 41.43 ? 98 TYR A CG 1 ATOM 754 C CD1 . TYR A 1 94 ? -28.230 10.903 -5.878 1.00 41.45 ? 98 TYR A CD1 1 ATOM 755 C CD2 . TYR A 1 94 ? -30.418 11.462 -5.071 1.00 40.93 ? 98 TYR A CD2 1 ATOM 756 C CE1 . TYR A 1 94 ? -28.557 9.547 -5.853 1.00 41.64 ? 98 TYR A CE1 1 ATOM 757 C CE2 . TYR A 1 94 ? -30.760 10.110 -5.044 1.00 41.04 ? 98 TYR A CE2 1 ATOM 758 C CZ . TYR A 1 94 ? -29.827 9.156 -5.436 1.00 41.81 ? 98 TYR A CZ 1 ATOM 759 O OH . TYR A 1 94 ? -30.161 7.816 -5.423 1.00 41.59 ? 98 TYR A OH 1 ATOM 760 N N . THR A 1 95 ? -27.894 13.500 -8.503 1.00 42.50 ? 99 THR A N 1 ATOM 761 C CA . THR A 1 95 ? -27.493 12.855 -9.746 1.00 42.90 ? 99 THR A CA 1 ATOM 762 C C . THR A 1 95 ? -26.980 11.457 -9.430 1.00 43.21 ? 99 THR A C 1 ATOM 763 O O . THR A 1 95 ? -26.171 11.272 -8.521 1.00 43.52 ? 99 THR A O 1 ATOM 764 C CB . THR A 1 95 ? -26.398 13.684 -10.480 1.00 42.93 ? 99 THR A CB 1 ATOM 765 O OG1 . THR A 1 95 ? -26.925 14.966 -10.856 1.00 42.86 ? 99 THR A OG1 1 ATOM 766 C CG2 . THR A 1 95 ? -25.903 12.968 -11.726 1.00 43.21 ? 99 THR A CG2 1 ATOM 767 N N . GLY A 1 96 ? -27.467 10.466 -10.158 1.00 43.38 ? 100 GLY A N 1 ATOM 768 C CA . GLY A 1 96 ? -26.928 9.126 -10.027 1.00 43.94 ? 100 GLY A CA 1 ATOM 769 C C . GLY A 1 96 ? -26.257 8.712 -11.320 1.00 44.49 ? 100 GLY A C 1 ATOM 770 O O . GLY A 1 96 ? -26.572 9.242 -12.390 1.00 44.39 ? 100 GLY A O 1 ATOM 771 N N . ILE A 1 97 ? -25.325 7.770 -11.227 1.00 44.86 ? 101 ILE A N 1 ATOM 772 C CA . ILE A 1 97 ? -24.732 7.191 -12.424 1.00 45.44 ? 101 ILE A CA 1 ATOM 773 C C . ILE A 1 97 ? -25.348 5.810 -12.667 1.00 45.91 ? 101 ILE A C 1 ATOM 774 O O . ILE A 1 97 ? -25.129 4.872 -11.895 1.00 45.92 ? 101 ILE A O 1 ATOM 775 C CB . ILE A 1 97 ? -23.195 7.102 -12.314 1.00 45.40 ? 101 ILE A CB 1 ATOM 776 C CG1 . ILE A 1 97 ? -22.609 8.400 -11.742 1.00 45.47 ? 101 ILE A CG1 1 ATOM 777 C CG2 . ILE A 1 97 ? -22.583 6.763 -13.658 1.00 45.34 ? 101 ILE A CG2 1 ATOM 778 C CD1 . ILE A 1 97 ? -22.829 9.650 -12.611 1.00 45.01 ? 101 ILE A CD1 1 ATOM 779 N N . ASP A 1 98 ? -26.139 5.703 -13.731 1.00 46.56 ? 102 ASP A N 1 ATOM 780 C CA . ASP A 1 98 ? -26.821 4.452 -14.058 1.00 47.25 ? 102 ASP A CA 1 ATOM 781 C C . ASP A 1 98 ? -25.844 3.411 -14.660 1.00 47.96 ? 102 ASP A C 1 ATOM 782 O O . ASP A 1 98 ? -24.678 3.742 -14.903 1.00 48.17 ? 102 ASP A O 1 ATOM 783 C CB . ASP A 1 98 ? -28.089 4.715 -14.911 1.00 47.00 ? 102 ASP A CB 1 ATOM 784 C CG . ASP A 1 98 ? -27.799 4.940 -16.392 1.00 46.77 ? 102 ASP A CG 1 ATOM 785 O OD1 . ASP A 1 98 ? -26.658 4.710 -16.852 1.00 45.58 ? 102 ASP A OD1 1 ATOM 786 O OD2 . ASP A 1 98 ? -28.745 5.347 -17.107 1.00 46.32 ? 102 ASP A OD2 1 ATOM 787 N N . PRO A 1 99 ? -26.302 2.157 -14.891 1.00 48.57 ? 103 PRO A N 1 ATOM 788 C CA . PRO A 1 99 ? -25.383 1.107 -15.352 1.00 48.83 ? 103 PRO A CA 1 ATOM 789 C C . PRO A 1 99 ? -24.733 1.375 -16.714 1.00 49.14 ? 103 PRO A C 1 ATOM 790 O O . PRO A 1 99 ? -23.709 0.770 -17.019 1.00 49.65 ? 103 PRO A O 1 ATOM 791 C CB . PRO A 1 99 ? -26.282 -0.124 -15.442 1.00 49.07 ? 103 PRO A CB 1 ATOM 792 C CG . PRO A 1 99 ? -27.672 0.432 -15.636 1.00 49.12 ? 103 PRO A CG 1 ATOM 793 C CD . PRO A 1 99 ? -27.681 1.642 -14.763 1.00 48.64 ? 103 PRO A CD 1 ATOM 794 N N . LYS A 1 100 ? -25.322 2.261 -17.518 1.00 49.24 ? 104 LYS A N 1 ATOM 795 C CA . LYS A 1 100 ? -24.731 2.696 -18.794 1.00 49.22 ? 104 LYS A CA 1 ATOM 796 C C . LYS A 1 100 ? -23.901 3.991 -18.658 1.00 48.84 ? 104 LYS A C 1 ATOM 797 O O . LYS A 1 100 ? -23.644 4.673 -19.651 1.00 48.76 ? 104 LYS A O 1 ATOM 798 C CB . LYS A 1 100 ? -25.825 2.854 -19.870 1.00 49.59 ? 104 LYS A CB 1 ATOM 799 C CG . LYS A 1 100 ? -26.273 1.535 -20.541 1.00 50.98 ? 104 LYS A CG 1 ATOM 800 C CD . LYS A 1 100 ? -27.803 1.469 -20.764 1.00 53.17 ? 104 LYS A CD 1 ATOM 801 C CE . LYS A 1 100 ? -28.255 2.149 -22.068 1.00 54.64 ? 104 LYS A CE 1 ATOM 802 N NZ . LYS A 1 100 ? -28.154 1.244 -23.263 1.00 54.85 ? 104 LYS A NZ 1 ATOM 803 N N . ASN A 1 101 ? -23.475 4.309 -17.432 1.00 48.38 ? 105 ASN A N 1 ATOM 804 C CA . ASN A 1 101 ? -22.671 5.514 -17.119 1.00 47.98 ? 105 ASN A CA 1 ATOM 805 C C . ASN A 1 101 ? -23.292 6.836 -17.557 1.00 47.37 ? 105 ASN A C 1 ATOM 806 O O . ASN A 1 101 ? -22.622 7.718 -18.081 1.00 47.23 ? 105 ASN A O 1 ATOM 807 C CB . ASN A 1 101 ? -21.218 5.373 -17.602 1.00 48.20 ? 105 ASN A CB 1 ATOM 808 C CG . ASN A 1 101 ? -20.479 4.255 -16.879 1.00 49.53 ? 105 ASN A CG 1 ATOM 809 O OD1 . ASN A 1 101 ? -19.739 4.499 -15.918 1.00 49.86 ? 105 ASN A OD1 1 ATOM 810 N ND2 . ASN A 1 101 ? -20.719 3.009 -17.308 1.00 49.94 ? 105 ASN A ND2 1 ATOM 811 N N . GLN A 1 102 ? -24.590 6.956 -17.315 1.00 47.03 ? 106 GLN A N 1 ATOM 812 C CA . GLN A 1 102 ? -25.359 8.138 -17.680 1.00 46.45 ? 106 GLN A CA 1 ATOM 813 C C . GLN A 1 102 ? -25.717 8.917 -16.431 1.00 46.06 ? 106 GLN A C 1 ATOM 814 O O . GLN A 1 102 ? -26.039 8.325 -15.392 1.00 45.90 ? 106 GLN A O 1 ATOM 815 C CB . GLN A 1 102 ? -26.641 7.735 -18.397 1.00 46.44 ? 106 GLN A CB 1 ATOM 816 C CG . GLN A 1 102 ? -26.417 6.918 -19.653 1.00 46.80 ? 106 GLN A CG 1 ATOM 817 C CD . GLN A 1 102 ? -27.563 7.051 -20.628 1.00 46.99 ? 106 GLN A CD 1 ATOM 818 O OE1 . GLN A 1 102 ? -28.728 6.849 -20.261 1.00 45.60 ? 106 GLN A OE1 1 ATOM 819 N NE2 . GLN A 1 102 ? -27.243 7.403 -21.884 1.00 45.66 ? 106 GLN A NE2 1 ATOM 820 N N . GLN A 1 103 ? -25.660 10.243 -16.537 1.00 45.30 ? 107 GLN A N 1 ATOM 821 C CA . GLN A 1 103 ? -25.947 11.103 -15.401 1.00 44.71 ? 107 GLN A CA 1 ATOM 822 C C . GLN A 1 103 ? -27.443 11.400 -15.314 1.00 44.51 ? 107 GLN A C 1 ATOM 823 O O . GLN A 1 103 ? -27.988 12.183 -16.093 1.00 44.67 ? 107 GLN A O 1 ATOM 824 C CB . GLN A 1 103 ? -25.101 12.375 -15.458 1.00 44.61 ? 107 GLN A CB 1 ATOM 825 C CG . GLN A 1 103 ? -23.618 12.135 -15.190 1.00 44.11 ? 107 GLN A CG 1 ATOM 826 C CD . GLN A 1 103 ? -22.716 13.258 -15.688 1.00 43.82 ? 107 GLN A CD 1 ATOM 827 O OE1 . GLN A 1 103 ? -23.184 14.338 -16.071 1.00 44.45 ? 107 GLN A OE1 1 ATOM 828 N NE2 . GLN A 1 103 ? -21.414 13.005 -15.680 1.00 42.53 ? 107 GLN A NE2 1 ATOM 829 N N . VAL A 1 104 ? -28.101 10.745 -14.365 1.00 44.08 ? 108 VAL A N 1 ATOM 830 C CA . VAL A 1 104 ? -29.546 10.843 -14.221 1.00 43.91 ? 108 VAL A CA 1 ATOM 831 C C . VAL A 1 104 ? -29.916 11.495 -12.897 1.00 44.07 ? 108 VAL A C 1 ATOM 832 O O . VAL A 1 104 ? -29.113 11.517 -11.954 1.00 43.85 ? 108 VAL A O 1 ATOM 833 C CB . VAL A 1 104 ? -30.254 9.458 -14.365 1.00 44.00 ? 108 VAL A CB 1 ATOM 834 C CG1 . VAL A 1 104 ? -29.889 8.801 -15.696 1.00 43.21 ? 108 VAL A CG1 1 ATOM 835 C CG2 . VAL A 1 104 ? -29.945 8.523 -13.169 1.00 43.48 ? 108 VAL A CG2 1 ATOM 836 N N . GLN A 1 105 ? -31.136 12.021 -12.838 1.00 44.24 ? 109 GLN A N 1 ATOM 837 C CA . GLN A 1 105 ? -31.602 12.754 -11.665 1.00 44.58 ? 109 GLN A CA 1 ATOM 838 C C . GLN A 1 105 ? -32.542 11.901 -10.820 1.00 44.92 ? 109 GLN A C 1 ATOM 839 O O . GLN A 1 105 ? -33.537 11.370 -11.324 1.00 44.95 ? 109 GLN A O 1 ATOM 840 C CB . GLN A 1 105 ? -32.262 14.082 -12.064 1.00 44.22 ? 109 GLN A CB 1 ATOM 841 C CG . GLN A 1 105 ? -31.470 14.935 -13.071 1.00 43.66 ? 109 GLN A CG 1 ATOM 842 C CD . GLN A 1 105 ? -29.964 14.941 -12.832 1.00 43.36 ? 109 GLN A CD 1 ATOM 843 O OE1 . GLN A 1 105 ? -29.492 15.061 -11.701 1.00 43.77 ? 109 GLN A OE1 1 ATOM 844 N NE2 . GLN A 1 105 ? -29.203 14.809 -13.908 1.00 42.89 ? 109 GLN A NE2 1 ATOM 845 N N . ASN A 1 106 ? -32.207 11.777 -9.538 1.00 45.12 ? 110 ASN A N 1 ATOM 846 C CA . ASN A 1 106 ? -32.927 10.915 -8.616 1.00 45.56 ? 110 ASN A CA 1 ATOM 847 C C . ASN A 1 106 ? -33.450 11.652 -7.387 1.00 46.02 ? 110 ASN A C 1 ATOM 848 O O . ASN A 1 106 ? -32.827 12.604 -6.921 1.00 46.28 ? 110 ASN A O 1 ATOM 849 C CB . ASN A 1 106 ? -32.014 9.771 -8.165 1.00 45.50 ? 110 ASN A CB 1 ATOM 850 C CG . ASN A 1 106 ? -31.559 8.891 -9.310 1.00 44.91 ? 110 ASN A CG 1 ATOM 851 O OD1 . ASN A 1 106 ? -32.298 8.661 -10.267 1.00 44.25 ? 110 ASN A OD1 1 ATOM 852 N ND2 . ASN A 1 106 ? -30.340 8.371 -9.203 1.00 44.23 ? 110 ASN A ND2 1 ATOM 853 N N . ILE A 1 107 ? -34.583 11.195 -6.856 1.00 46.57 ? 111 ILE A N 1 ATOM 854 C CA . ILE A 1 107 ? -35.140 11.755 -5.627 1.00 47.26 ? 111 ILE A CA 1 ATOM 855 C C . ILE A 1 107 ? -34.921 10.817 -4.434 1.00 47.89 ? 111 ILE A C 1 ATOM 856 O O . ILE A 1 107 ? -34.936 9.594 -4.589 1.00 47.56 ? 111 ILE A O 1 ATOM 857 C CB . ILE A 1 107 ? -36.653 12.136 -5.777 1.00 47.17 ? 111 ILE A CB 1 ATOM 858 C CG1 . ILE A 1 107 ? -37.103 13.065 -4.637 1.00 47.22 ? 111 ILE A CG1 1 ATOM 859 C CG2 . ILE A 1 107 ? -37.538 10.891 -5.872 1.00 47.15 ? 111 ILE A CG2 1 ATOM 860 C CD1 . ILE A 1 107 ? -38.477 13.715 -4.840 1.00 47.21 ? 111 ILE A CD1 1 ATOM 861 N N . ALA A 1 108 ? -34.695 11.410 -3.258 1.00 48.78 ? 112 ALA A N 1 ATOM 862 C CA . ALA A 1 108 ? -34.673 10.683 -1.984 1.00 49.61 ? 112 ALA A CA 1 ATOM 863 C C . ALA A 1 108 ? -35.596 11.336 -0.955 1.00 50.33 ? 112 ALA A C 1 ATOM 864 O O . ALA A 1 108 ? -35.667 12.564 -0.858 1.00 50.52 ? 112 ALA A O 1 ATOM 865 C CB . ALA A 1 108 ? -33.267 10.592 -1.446 1.00 49.36 ? 112 ALA A CB 1 ATOM 866 N N . GLU A 1 109 ? -36.317 10.504 -0.212 1.00 51.25 ? 113 GLU A N 1 ATOM 867 C CA . GLU A 1 109 ? -37.171 10.954 0.878 1.00 52.56 ? 113 GLU A CA 1 ATOM 868 C C . GLU A 1 109 ? -36.607 10.381 2.168 1.00 52.98 ? 113 GLU A C 1 ATOM 869 O O . GLU A 1 109 ? -35.983 9.311 2.140 1.00 52.90 ? 113 GLU A O 1 ATOM 870 C CB . GLU A 1 109 ? -38.596 10.430 0.709 1.00 52.58 ? 113 GLU A CB 1 ATOM 871 C CG . GLU A 1 109 ? -39.475 11.161 -0.296 1.00 53.42 ? 113 GLU A CG 1 ATOM 872 C CD . GLU A 1 109 ? -40.814 10.458 -0.494 1.00 53.92 ? 113 GLU A CD 1 ATOM 873 O OE1 . GLU A 1 109 ? -40.979 9.325 0.018 1.00 56.11 ? 113 GLU A OE1 1 ATOM 874 O OE2 . GLU A 1 109 ? -41.709 11.031 -1.157 1.00 56.09 ? 113 GLU A OE2 1 ATOM 875 N N . PRO A 1 110 ? -36.824 11.077 3.308 1.00 53.46 ? 114 PRO A N 1 ATOM 876 C CA . PRO A 1 110 ? -36.402 10.485 4.574 1.00 53.84 ? 114 PRO A CA 1 ATOM 877 C C . PRO A 1 110 ? -37.336 9.325 4.916 1.00 54.53 ? 114 PRO A C 1 ATOM 878 O O . PRO A 1 110 ? -38.526 9.377 4.577 1.00 54.18 ? 114 PRO A O 1 ATOM 879 C CB . PRO A 1 110 ? -36.566 11.634 5.577 1.00 53.70 ? 114 PRO A CB 1 ATOM 880 C CG . PRO A 1 110 ? -36.780 12.866 4.752 1.00 53.45 ? 114 PRO A CG 1 ATOM 881 C CD . PRO A 1 110 ? -37.448 12.395 3.511 1.00 53.19 ? 114 PRO A CD 1 ATOM 882 N N . LYS A 1 111 ? -36.795 8.287 5.558 1.00 55.34 ? 115 LYS A N 1 ATOM 883 C CA . LYS A 1 111 ? -37.565 7.086 5.909 1.00 55.96 ? 115 LYS A CA 1 ATOM 884 C C . LYS A 1 111 ? -38.467 7.321 7.119 1.00 56.42 ? 115 LYS A C 1 ATOM 885 O O . LYS A 1 111 ? -39.568 6.784 7.194 1.00 56.49 ? 115 LYS A O 1 ATOM 886 C CB . LYS A 1 111 ? -36.624 5.915 6.184 1.00 55.86 ? 115 LYS A CB 1 ATOM 887 C CG . LYS A 1 111 ? -37.278 4.537 6.113 1.00 56.31 ? 115 LYS A CG 1 ATOM 888 C CD . LYS A 1 111 ? -36.224 3.453 5.909 1.00 56.85 ? 115 LYS A CD 1 ATOM 889 C CE . LYS A 1 111 ? -35.712 3.454 4.466 1.00 56.87 ? 115 LYS A CE 1 ATOM 890 N NZ . LYS A 1 111 ? -34.299 3.012 4.359 1.00 56.27 ? 115 LYS A NZ 1 ATOM 891 N N . ASN A 1 112 ? -37.988 8.130 8.058 1.00 57.10 ? 116 ASN A N 1 ATOM 892 C CA . ASN A 1 112 ? -38.695 8.408 9.304 1.00 57.72 ? 116 ASN A CA 1 ATOM 893 C C . ASN A 1 112 ? -38.700 9.919 9.588 1.00 57.80 ? 116 ASN A C 1 ATOM 894 O O . ASN A 1 112 ? -37.773 10.455 10.209 1.00 57.92 ? 116 ASN A O 1 ATOM 895 C CB . ASN A 1 112 ? -38.036 7.608 10.439 1.00 57.89 ? 116 ASN A CB 1 ATOM 896 C CG . ASN A 1 112 ? -38.625 7.905 11.807 1.00 59.45 ? 116 ASN A CG 1 ATOM 897 O OD1 . ASN A 1 112 ? -39.620 8.626 11.939 1.00 59.93 ? 116 ASN A OD1 1 ATOM 898 N ND2 . ASN A 1 112 ? -37.992 7.352 12.842 1.00 61.84 ? 116 ASN A ND2 1 ATOM 899 N N . LEU A 1 113 ? -39.746 10.601 9.125 1.00 57.88 ? 117 LEU A N 1 ATOM 900 C CA . LEU A 1 113 ? -39.855 12.063 9.262 1.00 58.01 ? 117 LEU A CA 1 ATOM 901 C C . LEU A 1 113 ? -39.867 12.562 10.708 1.00 58.20 ? 117 LEU A C 1 ATOM 902 O O . LEU A 1 113 ? -39.902 13.777 10.951 1.00 58.20 ? 117 LEU A O 1 ATOM 903 C CB . LEU A 1 113 ? -41.087 12.583 8.520 1.00 57.92 ? 117 LEU A CB 1 ATOM 904 C CG . LEU A 1 113 ? -40.905 12.706 7.013 1.00 57.72 ? 117 LEU A CG 1 ATOM 905 C CD1 . LEU A 1 113 ? -42.238 12.578 6.283 1.00 57.29 ? 117 LEU A CD1 1 ATOM 906 C CD2 . LEU A 1 113 ? -40.206 14.017 6.700 1.00 56.82 ? 117 LEU A CD2 1 ATOM 907 N N . SER A 1 114 ? -39.840 11.613 11.649 1.00 58.33 ? 118 SER A N 1 ATOM 908 C CA . SER A 1 114 ? -39.782 11.898 13.085 1.00 58.28 ? 118 SER A CA 1 ATOM 909 C C . SER A 1 114 ? -38.346 11.839 13.603 1.00 58.16 ? 118 SER A C 1 ATOM 910 O O . SER A 1 114 ? -38.054 12.338 14.692 1.00 58.32 ? 118 SER A O 1 ATOM 911 C CB . SER A 1 114 ? -40.671 10.926 13.871 1.00 58.18 ? 118 SER A CB 1 ATOM 912 O OG . SER A 1 114 ? -42.022 11.040 13.469 1.00 58.13 ? 118 SER A OG 1 ATOM 913 N N . ASP A 1 115 ? -37.457 11.214 12.835 1.00 58.02 ? 119 ASP A N 1 ATOM 914 C CA . ASP A 1 115 ? -36.036 11.266 13.147 1.00 57.90 ? 119 ASP A CA 1 ATOM 915 C C . ASP A 1 115 ? -35.573 12.690 12.883 1.00 58.00 ? 119 ASP A C 1 ATOM 916 O O . ASP A 1 115 ? -35.690 13.181 11.755 1.00 58.29 ? 119 ASP A O 1 ATOM 917 C CB . ASP A 1 115 ? -35.229 10.277 12.304 1.00 57.59 ? 119 ASP A CB 1 ATOM 918 C CG . ASP A 1 115 ? -33.809 10.081 12.823 1.00 57.00 ? 119 ASP A CG 1 ATOM 919 O OD1 . ASP A 1 115 ? -33.414 10.733 13.816 1.00 56.02 ? 119 ASP A OD1 1 ATOM 920 O OD2 . ASP A 1 115 ? -33.085 9.255 12.231 1.00 56.38 ? 119 ASP A OD2 1 ATOM 921 N N . PRO A 1 116 ? -35.073 13.372 13.927 1.00 57.88 ? 120 PRO A N 1 ATOM 922 C CA . PRO A 1 116 ? -34.651 14.754 13.713 1.00 57.62 ? 120 PRO A CA 1 ATOM 923 C C . PRO A 1 116 ? -33.226 14.826 13.145 1.00 57.26 ? 120 PRO A C 1 ATOM 924 O O . PRO A 1 116 ? -32.820 15.875 12.621 1.00 57.29 ? 120 PRO A O 1 ATOM 925 C CB . PRO A 1 116 ? -34.735 15.363 15.113 1.00 57.60 ? 120 PRO A CB 1 ATOM 926 C CG . PRO A 1 116 ? -34.488 14.200 16.044 1.00 58.17 ? 120 PRO A CG 1 ATOM 927 C CD . PRO A 1 116 ? -34.869 12.928 15.320 1.00 57.85 ? 120 PRO A CD 1 ATOM 928 N N . TYR A 1 117 ? -32.491 13.714 13.244 1.00 56.48 ? 121 TYR A N 1 ATOM 929 C CA . TYR A 1 117 ? -31.168 13.596 12.650 1.00 55.76 ? 121 TYR A CA 1 ATOM 930 C C . TYR A 1 117 ? -31.223 13.022 11.226 1.00 55.04 ? 121 TYR A C 1 ATOM 931 O O . TYR A 1 117 ? -30.179 12.778 10.620 1.00 55.06 ? 121 TYR A O 1 ATOM 932 C CB . TYR A 1 117 ? -30.258 12.723 13.521 1.00 56.32 ? 121 TYR A CB 1 ATOM 933 C CG . TYR A 1 117 ? -29.994 13.229 14.927 1.00 57.21 ? 121 TYR A CG 1 ATOM 934 C CD1 . TYR A 1 117 ? -30.399 12.486 16.043 1.00 58.36 ? 121 TYR A CD1 1 ATOM 935 C CD2 . TYR A 1 117 ? -29.322 14.436 15.149 1.00 58.00 ? 121 TYR A CD2 1 ATOM 936 C CE1 . TYR A 1 117 ? -30.155 12.936 17.350 1.00 58.39 ? 121 TYR A CE1 1 ATOM 937 C CE2 . TYR A 1 117 ? -29.074 14.899 16.450 1.00 58.59 ? 121 TYR A CE2 1 ATOM 938 C CZ . TYR A 1 117 ? -29.492 14.143 17.545 1.00 58.49 ? 121 TYR A CZ 1 ATOM 939 O OH . TYR A 1 117 ? -29.244 14.592 18.829 1.00 58.37 ? 121 TYR A OH 1 ATOM 940 N N . LEU A 1 118 ? -32.437 12.802 10.709 1.00 54.13 ? 122 LEU A N 1 ATOM 941 C CA . LEU A 1 118 ? -32.689 12.232 9.361 1.00 53.12 ? 122 LEU A CA 1 ATOM 942 C C . LEU A 1 118 ? -31.663 11.197 8.900 1.00 52.43 ? 122 LEU A C 1 ATOM 943 O O . LEU A 1 118 ? -31.069 11.334 7.831 1.00 52.10 ? 122 LEU A O 1 ATOM 944 C CB . LEU A 1 118 ? -32.828 13.331 8.299 1.00 53.02 ? 122 LEU A CB 1 ATOM 945 C CG . LEU A 1 118 ? -33.916 14.399 8.397 1.00 52.87 ? 122 LEU A CG 1 ATOM 946 C CD1 . LEU A 1 118 ? -33.790 15.295 7.194 1.00 53.33 ? 122 LEU A CD1 1 ATOM 947 C CD2 . LEU A 1 118 ? -35.331 13.827 8.479 1.00 52.70 ? 122 LEU A CD2 1 ATOM 948 N N . ARG A 1 119 ? -31.493 10.161 9.714 1.00 51.89 ? 123 ARG A N 1 ATOM 949 C CA . ARG A 1 119 ? -30.467 9.123 9.537 1.00 51.72 ? 123 ARG A CA 1 ATOM 950 C C . ARG A 1 119 ? -30.589 8.287 8.245 1.00 50.56 ? 123 ARG A C 1 ATOM 951 O O . ARG A 1 119 ? -29.582 8.001 7.598 1.00 50.41 ? 123 ARG A O 1 ATOM 952 C CB . ARG A 1 119 ? -30.453 8.224 10.792 1.00 51.82 ? 123 ARG A CB 1 ATOM 953 C CG . ARG A 1 119 ? -29.373 7.145 10.877 1.00 52.69 ? 123 ARG A CG 1 ATOM 954 C CD . ARG A 1 119 ? -29.276 6.579 12.310 1.00 53.11 ? 123 ARG A CD 1 ATOM 955 N NE . ARG A 1 119 ? -28.320 7.335 13.125 1.00 57.03 ? 123 ARG A NE 1 ATOM 956 C CZ . ARG A 1 119 ? -28.626 8.344 13.947 1.00 58.50 ? 123 ARG A CZ 1 ATOM 957 N NH1 . ARG A 1 119 ? -29.889 8.745 14.113 1.00 58.98 ? 123 ARG A NH1 1 ATOM 958 N NH2 . ARG A 1 119 ? -27.655 8.953 14.622 1.00 58.67 ? 123 ARG A NH2 1 ATOM 959 N N . GLU A 1 120 ? -31.813 7.912 7.872 1.00 49.50 ? 124 GLU A N 1 ATOM 960 C CA . GLU A 1 120 ? -32.037 6.993 6.748 1.00 48.42 ? 124 GLU A CA 1 ATOM 961 C C . GLU A 1 120 ? -32.988 7.515 5.678 1.00 47.68 ? 124 GLU A C 1 ATOM 962 O O . GLU A 1 120 ? -34.049 8.076 5.978 1.00 47.64 ? 124 GLU A O 1 ATOM 963 C CB . GLU A 1 120 ? -32.584 5.672 7.252 1.00 48.57 ? 124 GLU A CB 1 ATOM 964 C CG . GLU A 1 120 ? -31.657 4.889 8.134 1.00 48.71 ? 124 GLU A CG 1 ATOM 965 C CD . GLU A 1 120 ? -32.243 3.540 8.442 1.00 49.42 ? 124 GLU A CD 1 ATOM 966 O OE1 . GLU A 1 120 ? -32.815 3.394 9.545 1.00 49.74 ? 124 GLU A OE1 1 ATOM 967 O OE2 . GLU A 1 120 ? -32.173 2.646 7.563 1.00 48.51 ? 124 GLU A OE2 1 ATOM 968 N N . TRP A 1 121 ? -32.617 7.279 4.424 1.00 46.69 ? 125 TRP A N 1 ATOM 969 C CA . TRP A 1 121 ? -33.324 7.858 3.296 1.00 45.94 ? 125 TRP A CA 1 ATOM 970 C C . TRP A 1 121 ? -33.809 6.774 2.364 1.00 46.11 ? 125 TRP A C 1 ATOM 971 O O . TRP A 1 121 ? -33.143 5.757 2.198 1.00 45.91 ? 125 TRP A O 1 ATOM 972 C CB . TRP A 1 121 ? -32.421 8.858 2.560 1.00 45.13 ? 125 TRP A CB 1 ATOM 973 C CG . TRP A 1 121 ? -32.176 10.104 3.366 1.00 44.33 ? 125 TRP A CG 1 ATOM 974 C CD1 . TRP A 1 121 ? -31.408 10.216 4.497 1.00 43.61 ? 125 TRP A CD1 1 ATOM 975 C CD2 . TRP A 1 121 ? -32.719 11.409 3.122 1.00 43.54 ? 125 TRP A CD2 1 ATOM 976 N NE1 . TRP A 1 121 ? -31.444 11.505 4.969 1.00 43.67 ? 125 TRP A NE1 1 ATOM 977 C CE2 . TRP A 1 121 ? -32.234 12.261 4.141 1.00 43.34 ? 125 TRP A CE2 1 ATOM 978 C CE3 . TRP A 1 121 ? -33.567 11.942 2.141 1.00 43.24 ? 125 TRP A CE3 1 ATOM 979 C CZ2 . TRP A 1 121 ? -32.565 13.615 4.206 1.00 43.15 ? 125 TRP A CZ2 1 ATOM 980 C CZ3 . TRP A 1 121 ? -33.899 13.288 2.210 1.00 43.63 ? 125 TRP A CZ3 1 ATOM 981 C CH2 . TRP A 1 121 ? -33.395 14.109 3.237 1.00 43.62 ? 125 TRP A CH2 1 ATOM 982 N N . LYS A 1 122 ? -34.981 6.994 1.769 1.00 46.46 ? 126 LYS A N 1 ATOM 983 C CA . LYS A 1 122 ? -35.563 6.037 0.841 1.00 46.71 ? 126 LYS A CA 1 ATOM 984 C C . LYS A 1 122 ? -35.681 6.598 -0.585 1.00 47.37 ? 126 LYS A C 1 ATOM 985 O O . LYS A 1 122 ? -36.137 7.724 -0.789 1.00 47.77 ? 126 LYS A O 1 ATOM 986 C CB . LYS A 1 122 ? -36.892 5.471 1.378 1.00 46.58 ? 126 LYS A CB 1 ATOM 987 C CG . LYS A 1 122 ? -38.137 6.342 1.273 1.00 46.38 ? 126 LYS A CG 1 ATOM 988 C CD . LYS A 1 122 ? -39.387 5.474 1.482 1.00 46.29 ? 126 LYS A CD 1 ATOM 989 C CE . LYS A 1 122 ? -40.681 6.284 1.588 1.00 44.86 ? 126 LYS A CE 1 ATOM 990 N NZ . LYS A 1 122 ? -40.932 6.815 2.953 1.00 42.98 ? 126 LYS A NZ 1 ATOM 991 N N . LYS A 1 123 ? -35.248 5.812 -1.566 1.00 47.76 ? 127 LYS A N 1 ATOM 992 C CA . LYS A 1 123 ? -35.226 6.263 -2.951 1.00 48.10 ? 127 LYS A CA 1 ATOM 993 C C . LYS A 1 123 ? -36.387 5.645 -3.715 1.00 48.44 ? 127 LYS A C 1 ATOM 994 O O . LYS A 1 123 ? -36.568 4.434 -3.697 1.00 48.54 ? 127 LYS A O 1 ATOM 995 C CB . LYS A 1 123 ? -33.899 5.887 -3.629 1.00 48.11 ? 127 LYS A CB 1 ATOM 996 C CG . LYS A 1 123 ? -32.647 6.134 -2.798 1.00 47.53 ? 127 LYS A CG 1 ATOM 997 C CD . LYS A 1 123 ? -31.472 5.431 -3.427 1.00 47.37 ? 127 LYS A CD 1 ATOM 998 C CE . LYS A 1 123 ? -30.383 5.153 -2.414 1.00 47.82 ? 127 LYS A CE 1 ATOM 999 N NZ . LYS A 1 123 ? -29.368 4.247 -3.015 1.00 48.09 ? 127 LYS A NZ 1 ATOM 1000 N N . SER A 1 124 ? -37.168 6.482 -4.390 1.00 48.94 ? 128 SER A N 1 ATOM 1001 C CA . SER A 1 124 ? -38.298 6.015 -5.175 1.00 49.60 ? 128 SER A CA 1 ATOM 1002 C C . SER A 1 124 ? -37.874 4.995 -6.239 1.00 49.93 ? 128 SER A C 1 ATOM 1003 O O . SER A 1 124 ? -36.833 5.155 -6.870 1.00 50.35 ? 128 SER A O 1 ATOM 1004 C CB . SER A 1 124 ? -38.999 7.194 -5.841 1.00 49.53 ? 128 SER A CB 1 ATOM 1005 O OG . SER A 1 124 ? -39.798 6.739 -6.922 1.00 50.42 ? 128 SER A OG 1 ATOM 1006 N N . PRO A 1 125 ? -38.687 3.949 -6.450 1.00 50.12 ? 129 PRO A N 1 ATOM 1007 C CA . PRO A 1 125 ? -38.416 3.014 -7.537 1.00 50.19 ? 129 PRO A CA 1 ATOM 1008 C C . PRO A 1 125 ? -38.638 3.659 -8.903 1.00 50.27 ? 129 PRO A C 1 ATOM 1009 O O . PRO A 1 125 ? -38.158 3.132 -9.907 1.00 50.26 ? 129 PRO A O 1 ATOM 1010 C CB . PRO A 1 125 ? -39.456 1.916 -7.317 1.00 50.28 ? 129 PRO A CB 1 ATOM 1011 C CG . PRO A 1 125 ? -40.595 2.619 -6.632 1.00 50.39 ? 129 PRO A CG 1 ATOM 1012 C CD . PRO A 1 125 ? -39.905 3.583 -5.704 1.00 50.35 ? 129 PRO A CD 1 ATOM 1013 N N . LEU A 1 126 ? -39.356 4.785 -8.932 1.00 50.17 ? 130 LEU A N 1 ATOM 1014 C CA . LEU A 1 126 ? -39.612 5.518 -10.177 1.00 50.28 ? 130 LEU A CA 1 ATOM 1015 C C . LEU A 1 126 ? -38.406 6.311 -10.707 1.00 50.14 ? 130 LEU A C 1 ATOM 1016 O O . LEU A 1 126 ? -38.460 6.844 -11.817 1.00 50.02 ? 130 LEU A O 1 ATOM 1017 C CB . LEU A 1 126 ? -40.845 6.420 -10.046 1.00 50.34 ? 130 LEU A CB 1 ATOM 1018 C CG . LEU A 1 126 ? -42.189 5.750 -9.700 1.00 51.57 ? 130 LEU A CG 1 ATOM 1019 C CD1 . LEU A 1 126 ? -43.323 6.782 -9.701 1.00 51.77 ? 130 LEU A CD1 1 ATOM 1020 C CD2 . LEU A 1 126 ? -42.540 4.553 -10.624 1.00 51.86 ? 130 LEU A CD2 1 ATOM 1021 N N . ASN A 1 127 ? -37.331 6.388 -9.918 1.00 50.01 ? 131 ASN A N 1 ATOM 1022 C CA . ASN A 1 127 ? -36.076 7.011 -10.354 1.00 49.82 ? 131 ASN A CA 1 ATOM 1023 C C . ASN A 1 127 ? -35.434 6.226 -11.495 1.00 49.85 ? 131 ASN A C 1 ATOM 1024 O O . ASN A 1 127 ? -35.519 4.997 -11.517 1.00 49.92 ? 131 ASN A O 1 ATOM 1025 C CB . ASN A 1 127 ? -35.076 7.099 -9.193 1.00 49.79 ? 131 ASN A CB 1 ATOM 1026 C CG . ASN A 1 127 ? -35.442 8.146 -8.174 1.00 49.18 ? 131 ASN A CG 1 ATOM 1027 O OD1 . ASN A 1 127 ? -35.740 9.286 -8.515 1.00 48.40 ? 131 ASN A OD1 1 ATOM 1028 N ND2 . ASN A 1 127 ? -35.396 7.769 -6.905 1.00 49.43 ? 131 ASN A ND2 1 ATOM 1029 N N . PRO A 1 128 ? -34.771 6.920 -12.438 1.00 49.81 ? 132 PRO A N 1 ATOM 1030 C CA . PRO A 1 128 ? -34.619 8.368 -12.516 1.00 49.70 ? 132 PRO A CA 1 ATOM 1031 C C . PRO A 1 128 ? -35.922 9.088 -12.799 1.00 49.42 ? 132 PRO A C 1 ATOM 1032 O O . PRO A 1 128 ? -36.724 8.617 -13.599 1.00 49.83 ? 132 PRO A O 1 ATOM 1033 C CB . PRO A 1 128 ? -33.651 8.562 -13.698 1.00 49.70 ? 132 PRO A CB 1 ATOM 1034 C CG . PRO A 1 128 ? -33.791 7.351 -14.520 1.00 49.69 ? 132 PRO A CG 1 ATOM 1035 C CD . PRO A 1 128 ? -34.061 6.240 -13.541 1.00 50.07 ? 132 PRO A CD 1 ATOM 1036 N N . LEU A 1 129 ? -36.117 10.219 -12.127 1.00 49.06 ? 133 LEU A N 1 ATOM 1037 C CA . LEU A 1 129 ? -37.180 11.160 -12.444 1.00 48.40 ? 133 LEU A CA 1 ATOM 1038 C C . LEU A 1 129 ? -36.793 11.993 -13.656 1.00 48.27 ? 133 LEU A C 1 ATOM 1039 O O . LEU A 1 129 ? -37.660 12.516 -14.355 1.00 48.42 ? 133 LEU A O 1 ATOM 1040 C CB . LEU A 1 129 ? -37.431 12.084 -11.257 1.00 48.30 ? 133 LEU A CB 1 ATOM 1041 C CG . LEU A 1 129 ? -38.507 11.725 -10.228 1.00 48.50 ? 133 LEU A CG 1 ATOM 1042 C CD1 . LEU A 1 129 ? -38.415 10.285 -9.752 1.00 48.07 ? 133 LEU A CD1 1 ATOM 1043 C CD2 . LEU A 1 129 ? -38.450 12.678 -9.042 1.00 48.40 ? 133 LEU A CD2 1 ATOM 1044 N N . MET A 1 130 ? -35.488 12.119 -13.899 1.00 48.01 ? 134 MET A N 1 ATOM 1045 C CA . MET A 1 130 ? -34.972 12.924 -15.008 1.00 47.87 ? 134 MET A CA 1 ATOM 1046 C C . MET A 1 130 ? -33.690 12.332 -15.603 1.00 47.85 ? 134 MET A C 1 ATOM 1047 O O . MET A 1 130 ? -32.692 12.163 -14.904 1.00 48.01 ? 134 MET A O 1 ATOM 1048 C CB . MET A 1 130 ? -34.726 14.362 -14.551 1.00 47.86 ? 134 MET A CB 1 ATOM 1049 C CG . MET A 1 130 ? -35.979 15.157 -14.251 1.00 47.53 ? 134 MET A CG 1 ATOM 1050 S SD . MET A 1 130 ? -35.627 16.682 -13.371 1.00 47.80 ? 134 MET A SD 1 ATOM 1051 C CE . MET A 1 130 ? -35.502 16.117 -11.678 1.00 46.98 ? 134 MET A CE 1 ATOM 1052 N N . ALA A 1 131 ? -33.722 12.028 -16.896 1.00 47.78 ? 135 ALA A N 1 ATOM 1053 C CA . ALA A 1 131 ? -32.612 11.355 -17.561 1.00 47.87 ? 135 ALA A CA 1 ATOM 1054 C C . ALA A 1 131 ? -32.399 11.850 -18.992 1.00 48.02 ? 135 ALA A C 1 ATOM 1055 O O . ALA A 1 131 ? -33.359 12.225 -19.674 1.00 47.79 ? 135 ALA A O 1 ATOM 1056 C CB . ALA A 1 131 ? -32.835 9.839 -17.554 1.00 47.77 ? 135 ALA A CB 1 ATOM 1057 N N . PRO A 1 132 ? -31.135 11.855 -19.457 1.00 48.26 ? 136 PRO A N 1 ATOM 1058 C CA . PRO A 1 132 ? -30.933 12.142 -20.866 1.00 48.73 ? 136 PRO A CA 1 ATOM 1059 C C . PRO A 1 132 ? -31.518 11.019 -21.720 1.00 49.43 ? 136 PRO A C 1 ATOM 1060 O O . PRO A 1 132 ? -31.526 9.854 -21.300 1.00 49.50 ? 136 PRO A O 1 ATOM 1061 C CB . PRO A 1 132 ? -29.407 12.189 -21.001 1.00 48.47 ? 136 PRO A CB 1 ATOM 1062 C CG . PRO A 1 132 ? -28.896 11.408 -19.862 1.00 48.14 ? 136 PRO A CG 1 ATOM 1063 C CD . PRO A 1 132 ? -29.862 11.616 -18.754 1.00 48.16 ? 136 PRO A CD 1 ATOM 1064 N N . ASP A 1 133 ? -32.031 11.375 -22.893 1.00 50.13 ? 137 ASP A N 1 ATOM 1065 C CA . ASP A 1 133 ? -32.480 10.379 -23.859 1.00 50.70 ? 137 ASP A CA 1 ATOM 1066 C C . ASP A 1 133 ? -32.305 10.869 -25.301 1.00 51.12 ? 137 ASP A C 1 ATOM 1067 O O . ASP A 1 133 ? -31.672 11.909 -25.538 1.00 51.10 ? 137 ASP A O 1 ATOM 1068 C CB . ASP A 1 133 ? -33.922 9.940 -23.570 1.00 50.49 ? 137 ASP A CB 1 ATOM 1069 C CG . ASP A 1 133 ? -34.918 11.070 -23.697 1.00 51.08 ? 137 ASP A CG 1 ATOM 1070 O OD1 . ASP A 1 133 ? -34.802 11.863 -24.654 1.00 50.48 ? 137 ASP A OD1 1 ATOM 1071 O OD2 . ASP A 1 133 ? -35.834 11.156 -22.843 1.00 51.64 ? 137 ASP A OD2 1 ATOM 1072 N N . ALA A 1 134 ? -32.858 10.107 -26.248 1.00 51.60 ? 138 ALA A N 1 ATOM 1073 C CA . ALA A 1 134 ? -32.778 10.425 -27.676 1.00 51.96 ? 138 ALA A CA 1 ATOM 1074 C C . ALA A 1 134 ? -33.780 11.517 -28.090 1.00 52.32 ? 138 ALA A C 1 ATOM 1075 O O . ALA A 1 134 ? -33.533 12.261 -29.039 1.00 52.31 ? 138 ALA A O 1 ATOM 1076 C CB . ALA A 1 134 ? -32.980 9.177 -28.494 1.00 51.86 ? 138 ALA A CB 1 ATOM 1077 N N . VAL A 1 135 ? -34.903 11.601 -27.376 1.00 52.60 ? 139 VAL A N 1 ATOM 1078 C CA . VAL A 1 135 ? -35.859 12.690 -27.556 1.00 52.87 ? 139 VAL A CA 1 ATOM 1079 C C . VAL A 1 135 ? -35.223 14.027 -27.140 1.00 52.89 ? 139 VAL A C 1 ATOM 1080 O O . VAL A 1 135 ? -35.111 14.929 -27.966 1.00 53.25 ? 139 VAL A O 1 ATOM 1081 C CB . VAL A 1 135 ? -37.178 12.470 -26.740 1.00 53.27 ? 139 VAL A CB 1 ATOM 1082 C CG1 . VAL A 1 135 ? -38.237 13.530 -27.102 1.00 53.23 ? 139 VAL A CG1 1 ATOM 1083 C CG2 . VAL A 1 135 ? -37.731 11.051 -26.930 1.00 53.29 ? 139 VAL A CG2 1 ATOM 1084 N N . ASN A 1 136 ? -34.806 14.154 -25.874 1.00 52.57 ? 140 ASN A N 1 ATOM 1085 C CA . ASN A 1 136 ? -34.236 15.417 -25.370 1.00 52.14 ? 140 ASN A CA 1 ATOM 1086 C C . ASN A 1 136 ? -32.827 15.728 -25.889 1.00 52.09 ? 140 ASN A C 1 ATOM 1087 O O . ASN A 1 136 ? -32.427 16.893 -25.951 1.00 52.17 ? 140 ASN A O 1 ATOM 1088 C CB . ASN A 1 136 ? -34.316 15.523 -23.830 1.00 51.82 ? 140 ASN A CB 1 ATOM 1089 C CG . ASN A 1 136 ? -33.488 14.463 -23.103 1.00 51.84 ? 140 ASN A CG 1 ATOM 1090 O OD1 . ASN A 1 136 ? -32.410 14.070 -23.544 1.00 52.64 ? 140 ASN A OD1 1 ATOM 1091 N ND2 . ASN A 1 136 ? -33.986 14.020 -21.959 1.00 51.43 ? 140 ASN A ND2 1 ATOM 1092 N N . GLY A 1 137 ? -32.085 14.682 -26.259 1.00 51.96 ? 141 GLY A N 1 ATOM 1093 C CA . GLY A 1 137 ? -30.744 14.825 -26.832 1.00 51.86 ? 141 GLY A CA 1 ATOM 1094 C C . GLY A 1 137 ? -29.719 15.467 -25.913 1.00 51.90 ? 141 GLY A C 1 ATOM 1095 O O . GLY A 1 137 ? -28.741 16.048 -26.376 1.00 51.99 ? 141 GLY A O 1 ATOM 1096 N N . ILE A 1 138 ? -29.958 15.366 -24.607 1.00 51.80 ? 142 ILE A N 1 ATOM 1097 C CA . ILE A 1 138 ? -29.047 15.853 -23.579 1.00 51.33 ? 142 ILE A CA 1 ATOM 1098 C C . ILE A 1 138 ? -27.804 14.955 -23.521 1.00 51.24 ? 142 ILE A C 1 ATOM 1099 O O . ILE A 1 138 ? -27.921 13.729 -23.615 1.00 50.95 ? 142 ILE A O 1 ATOM 1100 C CB . ILE A 1 138 ? -29.766 15.868 -22.209 1.00 51.33 ? 142 ILE A CB 1 ATOM 1101 C CG1 . ILE A 1 138 ? -30.931 16.873 -22.228 1.00 51.45 ? 142 ILE A CG1 1 ATOM 1102 C CG2 . ILE A 1 138 ? -28.782 16.130 -21.068 1.00 51.22 ? 142 ILE A CG2 1 ATOM 1103 C CD1 . ILE A 1 138 ? -31.788 16.892 -20.950 1.00 51.39 ? 142 ILE A CD1 1 ATOM 1104 N N . ASN A 1 139 ? -26.624 15.568 -23.391 1.00 51.16 ? 143 ASN A N 1 ATOM 1105 C CA . ASN A 1 139 ? -25.373 14.822 -23.240 1.00 51.21 ? 143 ASN A CA 1 ATOM 1106 C C . ASN A 1 139 ? -25.377 14.065 -21.922 1.00 50.56 ? 143 ASN A C 1 ATOM 1107 O O . ASN A 1 139 ? -25.467 14.664 -20.843 1.00 50.47 ? 143 ASN A O 1 ATOM 1108 C CB . ASN A 1 139 ? -24.159 15.754 -23.318 1.00 51.88 ? 143 ASN A CB 1 ATOM 1109 C CG . ASN A 1 139 ? -22.820 15.002 -23.373 1.00 54.42 ? 143 ASN A CG 1 ATOM 1110 O OD1 . ASN A 1 139 ? -22.676 13.903 -22.825 1.00 54.10 ? 143 ASN A OD1 1 ATOM 1111 N ND2 . ASN A 1 139 ? -21.825 15.627 -24.028 1.00 59.44 ? 143 ASN A ND2 1 ATOM 1112 N N . ALA A 1 140 ? -25.280 12.743 -22.022 1.00 49.60 ? 144 ALA A N 1 ATOM 1113 C CA . ALA A 1 140 ? -25.383 11.867 -20.861 1.00 48.44 ? 144 ALA A CA 1 ATOM 1114 C C . ALA A 1 140 ? -24.211 11.998 -19.890 1.00 47.65 ? 144 ALA A C 1 ATOM 1115 O O . ALA A 1 140 ? -24.324 11.624 -18.725 1.00 47.63 ? 144 ALA A O 1 ATOM 1116 C CB . ALA A 1 140 ? -25.553 10.425 -21.308 1.00 48.48 ? 144 ALA A CB 1 ATOM 1117 N N . SER A 1 141 ? -23.089 12.524 -20.365 1.00 46.69 ? 145 SER A N 1 ATOM 1118 C CA . SER A 1 141 ? -21.936 12.726 -19.495 1.00 45.89 ? 145 SER A CA 1 ATOM 1119 C C . SER A 1 141 ? -21.876 14.149 -18.961 1.00 45.15 ? 145 SER A C 1 ATOM 1120 O O . SER A 1 141 ? -20.860 14.557 -18.404 1.00 45.20 ? 145 SER A O 1 ATOM 1121 C CB . SER A 1 141 ? -20.644 12.399 -20.237 1.00 45.83 ? 145 SER A CB 1 ATOM 1122 O OG . SER A 1 141 ? -20.624 11.039 -20.597 1.00 46.21 ? 145 SER A OG 1 ATOM 1123 N N . SER A 1 142 ? -22.961 14.898 -19.139 1.00 44.06 ? 146 SER A N 1 ATOM 1124 C CA . SER A 1 142 ? -22.986 16.313 -18.807 1.00 43.13 ? 146 SER A CA 1 ATOM 1125 C C . SER A 1 142 ? -24.390 16.752 -18.432 1.00 42.03 ? 146 SER A C 1 ATOM 1126 O O . SER A 1 142 ? -24.975 17.629 -19.073 1.00 41.85 ? 146 SER A O 1 ATOM 1127 C CB . SER A 1 142 ? -22.461 17.140 -19.984 1.00 43.56 ? 146 SER A CB 1 ATOM 1128 O OG . SER A 1 142 ? -21.050 17.008 -20.103 1.00 45.23 ? 146 SER A OG 1 ATOM 1129 N N . PHE A 1 143 ? -24.924 16.132 -17.384 1.00 40.68 ? 147 PHE A N 1 ATOM 1130 C CA . PHE A 1 143 ? -26.291 16.385 -16.936 1.00 39.24 ? 147 PHE A CA 1 ATOM 1131 C C . PHE A 1 143 ? -26.333 16.128 -15.442 1.00 38.69 ? 147 PHE A C 1 ATOM 1132 O O . PHE A 1 143 ? -26.788 15.070 -15.008 1.00 38.61 ? 147 PHE A O 1 ATOM 1133 C CB . PHE A 1 143 ? -27.261 15.453 -17.684 1.00 38.79 ? 147 PHE A CB 1 ATOM 1134 C CG . PHE A 1 143 ? -28.719 15.751 -17.453 1.00 37.34 ? 147 PHE A CG 1 ATOM 1135 C CD1 . PHE A 1 143 ? -29.221 17.034 -17.600 1.00 36.54 ? 147 PHE A CD1 1 ATOM 1136 C CD2 . PHE A 1 143 ? -29.594 14.729 -17.119 1.00 36.08 ? 147 PHE A CD2 1 ATOM 1137 C CE1 . PHE A 1 143 ? -30.571 17.294 -17.391 1.00 36.77 ? 147 PHE A CE1 1 ATOM 1138 C CE2 . PHE A 1 143 ? -30.940 14.981 -16.912 1.00 35.79 ? 147 PHE A CE2 1 ATOM 1139 C CZ . PHE A 1 143 ? -31.431 16.262 -17.048 1.00 36.16 ? 147 PHE A CZ 1 ATOM 1140 N N . ARG A 1 144 ? -25.835 17.085 -14.661 1.00 37.98 ? 148 ARG A N 1 ATOM 1141 C CA . ARG A 1 144 ? -25.679 16.872 -13.219 1.00 37.70 ? 148 ARG A CA 1 ATOM 1142 C C . ARG A 1 144 ? -25.949 18.053 -12.285 1.00 37.29 ? 148 ARG A C 1 ATOM 1143 O O . ARG A 1 144 ? -26.034 19.199 -12.717 1.00 37.01 ? 148 ARG A O 1 ATOM 1144 C CB . ARG A 1 144 ? -24.322 16.211 -12.896 1.00 37.53 ? 148 ARG A CB 1 ATOM 1145 C CG . ARG A 1 144 ? -23.084 17.064 -13.159 1.00 37.83 ? 148 ARG A CG 1 ATOM 1146 C CD . ARG A 1 144 ? -21.825 16.225 -12.980 1.00 37.72 ? 148 ARG A CD 1 ATOM 1147 N NE . ARG A 1 144 ? -20.614 16.879 -13.476 1.00 37.80 ? 148 ARG A NE 1 ATOM 1148 C CZ . ARG A 1 144 ? -20.182 16.818 -14.733 1.00 37.56 ? 148 ARG A CZ 1 ATOM 1149 N NH1 . ARG A 1 144 ? -20.865 16.136 -15.636 1.00 37.48 ? 148 ARG A NH1 1 ATOM 1150 N NH2 . ARG A 1 144 ? -19.069 17.449 -15.090 1.00 37.00 ? 148 ARG A NH2 1 ATOM 1151 N N . ASP A 1 145 ? -26.093 17.725 -11.000 1.00 37.12 ? 149 ASP A N 1 ATOM 1152 C CA . ASP A 1 145 ? -26.209 18.677 -9.888 1.00 37.14 ? 149 ASP A CA 1 ATOM 1153 C C . ASP A 1 145 ? -27.498 19.494 -9.918 1.00 37.04 ? 149 ASP A C 1 ATOM 1154 O O . ASP A 1 145 ? -27.465 20.702 -10.171 1.00 37.02 ? 149 ASP A O 1 ATOM 1155 C CB . ASP A 1 145 ? -24.995 19.615 -9.783 1.00 37.24 ? 149 ASP A CB 1 ATOM 1156 C CG . ASP A 1 145 ? -23.672 18.907 -9.994 1.00 37.34 ? 149 ASP A CG 1 ATOM 1157 O OD1 . ASP A 1 145 ? -23.577 17.691 -9.743 1.00 37.34 ? 149 ASP A OD1 1 ATOM 1158 O OD2 . ASP A 1 145 ? -22.712 19.587 -10.417 1.00 38.52 ? 149 ASP A OD2 1 ATOM 1159 N N . PRO A 1 146 ? -28.639 18.844 -9.624 1.00 36.98 ? 150 PRO A N 1 ATOM 1160 C CA . PRO A 1 146 ? -29.898 19.575 -9.509 1.00 36.67 ? 150 PRO A CA 1 ATOM 1161 C C . PRO A 1 146 ? -29.840 20.564 -8.350 1.00 36.49 ? 150 PRO A C 1 ATOM 1162 O O . PRO A 1 146 ? -29.120 20.340 -7.378 1.00 36.10 ? 150 PRO A O 1 ATOM 1163 C CB . PRO A 1 146 ? -30.919 18.473 -9.219 1.00 36.61 ? 150 PRO A CB 1 ATOM 1164 C CG . PRO A 1 146 ? -30.125 17.350 -8.664 1.00 36.52 ? 150 PRO A CG 1 ATOM 1165 C CD . PRO A 1 146 ? -28.815 17.402 -9.363 1.00 36.98 ? 150 PRO A CD 1 ATOM 1166 N N . THR A 1 147 ? -30.581 21.657 -8.470 1.00 36.58 ? 151 THR A N 1 ATOM 1167 C CA . THR A 1 147 ? -30.614 22.672 -7.432 1.00 36.66 ? 151 THR A CA 1 ATOM 1168 C C . THR A 1 147 ? -31.698 22.367 -6.401 1.00 37.15 ? 151 THR A C 1 ATOM 1169 O O . THR A 1 147 ? -32.395 21.348 -6.480 1.00 36.98 ? 151 THR A O 1 ATOM 1170 C CB . THR A 1 147 ? -30.869 24.063 -8.025 1.00 36.45 ? 151 THR A CB 1 ATOM 1171 O OG1 . THR A 1 147 ? -32.073 24.043 -8.792 1.00 35.99 ? 151 THR A OG1 1 ATOM 1172 C CG2 . THR A 1 147 ? -29.734 24.478 -8.926 1.00 36.57 ? 151 THR A CG2 1 ATOM 1173 N N . THR A 1 148 ? -31.809 23.242 -5.410 1.00 37.71 ? 152 THR A N 1 ATOM 1174 C CA . THR A 1 148 ? -33.010 23.303 -4.602 1.00 38.39 ? 152 THR A CA 1 ATOM 1175 C C . THR A 1 148 ? -34.100 23.780 -5.561 1.00 39.04 ? 152 THR A C 1 ATOM 1176 O O . THR A 1 148 ? -33.814 24.540 -6.490 1.00 39.18 ? 152 THR A O 1 ATOM 1177 C CB . THR A 1 148 ? -32.815 24.262 -3.413 1.00 38.26 ? 152 THR A CB 1 ATOM 1178 O OG1 . THR A 1 148 ? -31.892 23.673 -2.486 1.00 38.16 ? 152 THR A OG1 1 ATOM 1179 C CG2 . THR A 1 148 ? -34.118 24.549 -2.705 1.00 37.70 ? 152 THR A CG2 1 ATOM 1180 N N . ALA A 1 149 ? -35.328 23.306 -5.375 1.00 39.68 ? 153 ALA A N 1 ATOM 1181 C CA . ALA A 1 149 ? -36.410 23.667 -6.281 1.00 40.48 ? 153 ALA A CA 1 ATOM 1182 C C . ALA A 1 149 ? -37.260 24.831 -5.749 1.00 41.13 ? 153 ALA A C 1 ATOM 1183 O O . ALA A 1 149 ? -37.368 25.028 -4.543 1.00 41.37 ? 153 ALA A O 1 ATOM 1184 C CB . ALA A 1 149 ? -37.265 22.454 -6.581 1.00 40.46 ? 153 ALA A CB 1 ATOM 1185 N N . TRP A 1 150 ? -37.850 25.606 -6.657 1.00 42.00 ? 154 TRP A N 1 ATOM 1186 C CA . TRP A 1 150 ? -38.703 26.730 -6.270 1.00 42.67 ? 154 TRP A CA 1 ATOM 1187 C C . TRP A 1 150 ? -40.089 26.651 -6.892 1.00 43.87 ? 154 TRP A C 1 ATOM 1188 O O . TRP A 1 150 ? -40.224 26.395 -8.087 1.00 44.25 ? 154 TRP A O 1 ATOM 1189 C CB . TRP A 1 150 ? -38.040 28.073 -6.592 1.00 41.87 ? 154 TRP A CB 1 ATOM 1190 C CG . TRP A 1 150 ? -37.771 28.346 -8.051 1.00 40.99 ? 154 TRP A CG 1 ATOM 1191 C CD1 . TRP A 1 150 ? -38.529 29.109 -8.891 1.00 40.03 ? 154 TRP A CD1 1 ATOM 1192 C CD2 . TRP A 1 150 ? -36.646 27.890 -8.828 1.00 40.71 ? 154 TRP A CD2 1 ATOM 1193 N NE1 . TRP A 1 150 ? -37.961 29.146 -10.146 1.00 40.17 ? 154 TRP A NE1 1 ATOM 1194 C CE2 . TRP A 1 150 ? -36.803 28.413 -10.135 1.00 40.58 ? 154 TRP A CE2 1 ATOM 1195 C CE3 . TRP A 1 150 ? -35.520 27.099 -8.547 1.00 39.58 ? 154 TRP A CE3 1 ATOM 1196 C CZ2 . TRP A 1 150 ? -35.877 28.164 -11.159 1.00 40.32 ? 154 TRP A CZ2 1 ATOM 1197 C CZ3 . TRP A 1 150 ? -34.600 26.852 -9.570 1.00 39.89 ? 154 TRP A CZ3 1 ATOM 1198 C CH2 . TRP A 1 150 ? -34.789 27.379 -10.858 1.00 40.30 ? 154 TRP A CH2 1 ATOM 1199 N N . LEU A 1 151 ? -41.111 26.872 -6.070 1.00 45.28 ? 155 LEU A N 1 ATOM 1200 C CA . LEU A 1 151 ? -42.493 26.804 -6.511 1.00 46.70 ? 155 LEU A CA 1 ATOM 1201 C C . LEU A 1 151 ? -42.917 28.110 -7.170 1.00 47.89 ? 155 LEU A C 1 ATOM 1202 O O . LEU A 1 151 ? -42.769 29.181 -6.581 1.00 48.36 ? 155 LEU A O 1 ATOM 1203 C CB . LEU A 1 151 ? -43.389 26.481 -5.317 1.00 46.73 ? 155 LEU A CB 1 ATOM 1204 C CG . LEU A 1 151 ? -44.809 25.922 -5.510 1.00 47.26 ? 155 LEU A CG 1 ATOM 1205 C CD1 . LEU A 1 151 ? -44.964 24.994 -6.733 1.00 46.94 ? 155 LEU A CD1 1 ATOM 1206 C CD2 . LEU A 1 151 ? -45.252 25.219 -4.231 1.00 46.43 ? 155 LEU A CD2 1 ATOM 1207 N N . GLY A 1 152 ? -43.439 28.023 -8.391 1.00 49.14 ? 156 GLY A N 1 ATOM 1208 C CA . GLY A 1 152 ? -43.879 29.211 -9.135 1.00 50.93 ? 156 GLY A CA 1 ATOM 1209 C C . GLY A 1 152 ? -45.306 29.707 -8.867 1.00 52.33 ? 156 GLY A C 1 ATOM 1210 O O . GLY A 1 152 ? -46.094 29.061 -8.149 1.00 52.43 ? 156 GLY A O 1 ATOM 1211 N N . GLN A 1 153 ? -45.638 30.860 -9.458 1.00 53.35 ? 157 GLN A N 1 ATOM 1212 C CA . GLN A 1 153 ? -46.976 31.459 -9.355 1.00 54.15 ? 157 GLN A CA 1 ATOM 1213 C C . GLN A 1 153 ? -48.066 30.498 -9.854 1.00 54.10 ? 157 GLN A C 1 ATOM 1214 O O . GLN A 1 153 ? -49.155 30.449 -9.291 1.00 54.30 ? 157 GLN A O 1 ATOM 1215 C CB . GLN A 1 153 ? -47.030 32.785 -10.138 1.00 54.61 ? 157 GLN A CB 1 ATOM 1216 C CG . GLN A 1 153 ? -48.219 33.718 -9.793 1.00 56.11 ? 157 GLN A CG 1 ATOM 1217 C CD . GLN A 1 153 ? -47.911 34.720 -8.664 1.00 57.84 ? 157 GLN A CD 1 ATOM 1218 O OE1 . GLN A 1 153 ? -46.796 35.253 -8.564 1.00 58.15 ? 157 GLN A OE1 1 ATOM 1219 N NE2 . GLN A 1 153 ? -48.909 34.980 -7.818 1.00 57.39 ? 157 GLN A NE2 1 ATOM 1220 N N . ASP A 1 154 ? -47.759 29.731 -10.901 1.00 53.98 ? 158 ASP A N 1 ATOM 1221 C CA . ASP A 1 154 ? -48.718 28.780 -11.481 1.00 53.88 ? 158 ASP A CA 1 ATOM 1222 C C . ASP A 1 154 ? -48.814 27.463 -10.699 1.00 53.64 ? 158 ASP A C 1 ATOM 1223 O O . ASP A 1 154 ? -49.290 26.460 -11.232 1.00 53.46 ? 158 ASP A O 1 ATOM 1224 C CB . ASP A 1 154 ? -48.405 28.512 -12.970 1.00 53.93 ? 158 ASP A CB 1 ATOM 1225 C CG . ASP A 1 154 ? -46.922 28.282 -13.233 1.00 54.47 ? 158 ASP A CG 1 ATOM 1226 O OD1 . ASP A 1 154 ? -46.433 28.692 -14.309 1.00 53.96 ? 158 ASP A OD1 1 ATOM 1227 O OD2 . ASP A 1 154 ? -46.242 27.704 -12.358 1.00 55.40 ? 158 ASP A OD2 1 ATOM 1228 N N . LYS A 1 155 ? -48.374 27.484 -9.438 1.00 53.40 ? 159 LYS A N 1 ATOM 1229 C CA . LYS A 1 155 ? -48.290 26.282 -8.586 1.00 53.15 ? 159 LYS A CA 1 ATOM 1230 C C . LYS A 1 155 ? -47.545 25.117 -9.245 1.00 52.41 ? 159 LYS A C 1 ATOM 1231 O O . LYS A 1 155 ? -47.972 23.962 -9.165 1.00 52.70 ? 159 LYS A O 1 ATOM 1232 C CB . LYS A 1 155 ? -49.674 25.858 -8.070 1.00 53.01 ? 159 LYS A CB 1 ATOM 1233 C CG . LYS A 1 155 ? -50.124 26.681 -6.851 1.00 54.13 ? 159 LYS A CG 1 ATOM 1234 C CD . LYS A 1 155 ? -51.566 26.395 -6.420 1.00 53.94 ? 159 LYS A CD 1 ATOM 1235 C CE . LYS A 1 155 ? -52.559 27.275 -7.168 1.00 54.81 ? 159 LYS A CE 1 ATOM 1236 N NZ . LYS A 1 155 ? -53.944 26.974 -6.725 1.00 55.29 ? 159 LYS A NZ 1 ATOM 1237 N N . LYS A 1 156 ? -46.417 25.440 -9.877 1.00 51.48 ? 160 LYS A N 1 ATOM 1238 C CA . LYS A 1 156 ? -45.632 24.476 -10.648 1.00 50.37 ? 160 LYS A CA 1 ATOM 1239 C C . LYS A 1 156 ? -44.142 24.597 -10.285 1.00 49.40 ? 160 LYS A C 1 ATOM 1240 O O . LYS A 1 156 ? -43.570 25.697 -10.283 1.00 49.17 ? 160 LYS A O 1 ATOM 1241 C CB . LYS A 1 156 ? -45.855 24.723 -12.145 1.00 50.55 ? 160 LYS A CB 1 ATOM 1242 C CG . LYS A 1 156 ? -45.888 23.481 -13.023 1.00 51.06 ? 160 LYS A CG 1 ATOM 1243 C CD . LYS A 1 156 ? -46.666 23.735 -14.322 1.00 51.62 ? 160 LYS A CD 1 ATOM 1244 C CE . LYS A 1 156 ? -45.926 24.690 -15.256 1.00 52.64 ? 160 LYS A CE 1 ATOM 1245 N NZ . LYS A 1 156 ? -46.574 24.831 -16.598 1.00 52.32 ? 160 LYS A NZ 1 ATOM 1246 N N . TRP A 1 157 ? -43.526 23.461 -9.973 1.00 48.00 ? 161 TRP A N 1 ATOM 1247 C CA . TRP A 1 157 ? -42.148 23.424 -9.499 1.00 46.67 ? 161 TRP A CA 1 ATOM 1248 C C . TRP A 1 157 ? -41.151 23.634 -10.605 1.00 45.95 ? 161 TRP A C 1 ATOM 1249 O O . TRP A 1 157 ? -41.309 23.104 -11.707 1.00 45.84 ? 161 TRP A O 1 ATOM 1250 C CB . TRP A 1 157 ? -41.852 22.097 -8.799 1.00 46.68 ? 161 TRP A CB 1 ATOM 1251 C CG . TRP A 1 157 ? -42.429 22.036 -7.429 1.00 46.33 ? 161 TRP A CG 1 ATOM 1252 C CD1 . TRP A 1 157 ? -43.585 21.427 -7.056 1.00 45.57 ? 161 TRP A CD1 1 ATOM 1253 C CD2 . TRP A 1 157 ? -41.889 22.639 -6.249 1.00 45.99 ? 161 TRP A CD2 1 ATOM 1254 N NE1 . TRP A 1 157 ? -43.798 21.606 -5.713 1.00 45.67 ? 161 TRP A NE1 1 ATOM 1255 C CE2 . TRP A 1 157 ? -42.773 22.348 -5.193 1.00 45.64 ? 161 TRP A CE2 1 ATOM 1256 C CE3 . TRP A 1 157 ? -40.741 23.396 -5.983 1.00 46.26 ? 161 TRP A CE3 1 ATOM 1257 C CZ2 . TRP A 1 157 ? -42.547 22.780 -3.887 1.00 46.14 ? 161 TRP A CZ2 1 ATOM 1258 C CZ3 . TRP A 1 157 ? -40.512 23.828 -4.683 1.00 46.23 ? 161 TRP A CZ3 1 ATOM 1259 C CH2 . TRP A 1 157 ? -41.413 23.517 -3.650 1.00 46.41 ? 161 TRP A CH2 1 ATOM 1260 N N . ARG A 1 158 ? -40.126 24.424 -10.294 1.00 45.04 ? 162 ARG A N 1 ATOM 1261 C CA . ARG A 1 158 ? -38.958 24.592 -11.160 1.00 44.01 ? 162 ARG A CA 1 ATOM 1262 C C . ARG A 1 158 ? -37.677 24.083 -10.489 1.00 43.09 ? 162 ARG A C 1 ATOM 1263 O O . ARG A 1 158 ? -37.513 24.176 -9.267 1.00 42.69 ? 162 ARG A O 1 ATOM 1264 C CB . ARG A 1 158 ? -38.778 26.053 -11.570 1.00 43.85 ? 162 ARG A CB 1 ATOM 1265 C CG . ARG A 1 158 ? -39.531 26.456 -12.806 1.00 44.40 ? 162 ARG A CG 1 ATOM 1266 C CD . ARG A 1 158 ? -40.972 26.800 -12.472 1.00 45.78 ? 162 ARG A CD 1 ATOM 1267 N NE . ARG A 1 158 ? -41.702 27.407 -13.590 1.00 45.73 ? 162 ARG A NE 1 ATOM 1268 C CZ . ARG A 1 158 ? -42.995 27.713 -13.539 1.00 45.99 ? 162 ARG A CZ 1 ATOM 1269 N NH1 . ARG A 1 158 ? -43.686 27.462 -12.434 1.00 46.41 ? 162 ARG A NH1 1 ATOM 1270 N NH2 . ARG A 1 158 ? -43.599 28.265 -14.581 1.00 46.19 ? 162 ARG A NH2 1 ATOM 1271 N N . VAL A 1 159 ? -36.788 23.532 -11.310 1.00 41.92 ? 163 VAL A N 1 ATOM 1272 C CA . VAL A 1 159 ? -35.466 23.110 -10.883 1.00 40.97 ? 163 VAL A CA 1 ATOM 1273 C C . VAL A 1 159 ? -34.577 23.212 -12.103 1.00 40.68 ? 163 VAL A C 1 ATOM 1274 O O . VAL A 1 159 ? -35.049 23.057 -13.235 1.00 40.39 ? 163 VAL A O 1 ATOM 1275 C CB . VAL A 1 159 ? -35.461 21.666 -10.305 1.00 40.78 ? 163 VAL A CB 1 ATOM 1276 C CG1 . VAL A 1 159 ? -35.604 20.621 -11.403 1.00 41.06 ? 163 VAL A CG1 1 ATOM 1277 C CG2 . VAL A 1 159 ? -34.207 21.402 -9.506 1.00 40.36 ? 163 VAL A CG2 1 ATOM 1278 N N . ILE A 1 160 ? -33.300 23.501 -11.880 1.00 40.40 ? 164 ILE A N 1 ATOM 1279 C CA . ILE A 1 160 ? -32.344 23.566 -12.977 1.00 40.28 ? 164 ILE A CA 1 ATOM 1280 C C . ILE A 1 160 ? -31.227 22.556 -12.768 1.00 40.59 ? 164 ILE A C 1 ATOM 1281 O O . ILE A 1 160 ? -30.953 22.141 -11.640 1.00 40.67 ? 164 ILE A O 1 ATOM 1282 C CB . ILE A 1 160 ? -31.780 24.988 -13.206 1.00 40.06 ? 164 ILE A CB 1 ATOM 1283 C CG1 . ILE A 1 160 ? -31.319 25.602 -11.883 1.00 40.44 ? 164 ILE A CG1 1 ATOM 1284 C CG2 . ILE A 1 160 ? -32.818 25.871 -13.903 1.00 39.07 ? 164 ILE A CG2 1 ATOM 1285 C CD1 . ILE A 1 160 ? -30.212 26.609 -12.033 1.00 41.57 ? 164 ILE A CD1 1 ATOM 1286 N N . ILE A 1 161 ? -30.603 22.148 -13.865 1.00 40.83 ? 165 ILE A N 1 ATOM 1287 C CA . ILE A 1 161 ? -29.559 21.147 -13.818 1.00 41.44 ? 165 ILE A CA 1 ATOM 1288 C C . ILE A 1 161 ? -28.393 21.606 -14.680 1.00 41.81 ? 165 ILE A C 1 ATOM 1289 O O . ILE A 1 161 ? -28.596 22.074 -15.809 1.00 42.21 ? 165 ILE A O 1 ATOM 1290 C CB . ILE A 1 161 ? -30.085 19.790 -14.316 1.00 41.53 ? 165 ILE A CB 1 ATOM 1291 C CG1 . ILE A 1 161 ? -31.315 19.369 -13.510 1.00 41.96 ? 165 ILE A CG1 1 ATOM 1292 C CG2 . ILE A 1 161 ? -29.002 18.719 -14.221 1.00 41.53 ? 165 ILE A CG2 1 ATOM 1293 C CD1 . ILE A 1 161 ? -32.279 18.528 -14.290 1.00 43.28 ? 165 ILE A CD1 1 ATOM 1294 N N . GLY A 1 162 ? -27.178 21.477 -14.153 1.00 41.88 ? 166 GLY A N 1 ATOM 1295 C CA . GLY A 1 162 ? -25.992 21.919 -14.875 1.00 42.47 ? 166 GLY A CA 1 ATOM 1296 C C . GLY A 1 162 ? -25.673 21.043 -16.071 1.00 42.83 ? 166 GLY A C 1 ATOM 1297 O O . GLY A 1 162 ? -25.649 19.817 -15.956 1.00 42.63 ? 166 GLY A O 1 ATOM 1298 N N . SER A 1 163 ? -25.410 21.671 -17.216 1.00 43.48 ? 167 SER A N 1 ATOM 1299 C CA . SER A 1 163 ? -25.151 20.931 -18.464 1.00 44.09 ? 167 SER A CA 1 ATOM 1300 C C . SER A 1 163 ? -24.276 21.680 -19.477 1.00 44.66 ? 167 SER A C 1 ATOM 1301 O O . SER A 1 163 ? -23.733 22.748 -19.180 1.00 44.67 ? 167 SER A O 1 ATOM 1302 C CB . SER A 1 163 ? -26.479 20.540 -19.125 1.00 43.93 ? 167 SER A CB 1 ATOM 1303 O OG . SER A 1 163 ? -26.301 19.501 -20.068 1.00 43.25 ? 167 SER A OG 1 ATOM 1304 N N . LYS A 1 164 ? -24.140 21.088 -20.667 1.00 45.44 ? 168 LYS A N 1 ATOM 1305 C CA . LYS A 1 164 ? -23.504 21.723 -21.824 1.00 46.09 ? 168 LYS A CA 1 ATOM 1306 C C . LYS A 1 164 ? -23.865 21.022 -23.135 1.00 46.68 ? 168 LYS A C 1 ATOM 1307 O O . LYS A 1 164 ? -23.945 19.788 -23.187 1.00 46.53 ? 168 LYS A O 1 ATOM 1308 C CB . LYS A 1 164 ? -21.986 21.769 -21.665 1.00 45.93 ? 168 LYS A CB 1 ATOM 1309 C CG . LYS A 1 164 ? -21.338 20.418 -21.492 1.00 46.27 ? 168 LYS A CG 1 ATOM 1310 C CD . LYS A 1 164 ? -19.869 20.469 -21.860 1.00 46.44 ? 168 LYS A CD 1 ATOM 1311 C CE . LYS A 1 164 ? -19.347 19.076 -22.095 1.00 47.06 ? 168 LYS A CE 1 ATOM 1312 N NZ . LYS A 1 164 ? -17.912 19.017 -21.790 1.00 48.70 ? 168 LYS A NZ 1 ATOM 1313 N N . ILE A 1 165 ? -24.080 21.805 -24.192 1.00 47.49 ? 169 ILE A N 1 ATOM 1314 C CA . ILE A 1 165 ? -24.237 21.214 -25.521 1.00 48.74 ? 169 ILE A CA 1 ATOM 1315 C C . ILE A 1 165 ? -22.861 20.905 -26.156 1.00 49.19 ? 169 ILE A C 1 ATOM 1316 O O . ILE A 1 165 ? -22.518 19.727 -26.371 1.00 49.66 ? 169 ILE A O 1 ATOM 1317 C CB . ILE A 1 165 ? -25.200 22.004 -26.482 1.00 48.80 ? 169 ILE A CB 1 ATOM 1318 C CG1 . ILE A 1 165 ? -24.537 23.275 -27.028 1.00 49.31 ? 169 ILE A CG1 1 ATOM 1319 C CG2 . ILE A 1 165 ? -26.570 22.275 -25.814 1.00 48.44 ? 169 ILE A CG2 1 ATOM 1320 C CD1 . ILE A 1 165 ? -25.117 23.774 -28.372 1.00 49.41 ? 169 ILE A CD1 1 ATOM 1321 N N . HIS A 1 166 ? -22.072 21.945 -26.434 1.00 49.24 ? 170 HIS A N 1 ATOM 1322 C CA . HIS A 1 166 ? -20.712 21.739 -26.940 1.00 49.50 ? 170 HIS A CA 1 ATOM 1323 C C . HIS A 1 166 ? -19.708 22.476 -26.073 1.00 49.56 ? 170 HIS A C 1 ATOM 1324 O O . HIS A 1 166 ? -19.175 21.900 -25.132 1.00 49.91 ? 170 HIS A O 1 ATOM 1325 C CB . HIS A 1 166 ? -20.592 22.129 -28.418 1.00 49.67 ? 170 HIS A CB 1 ATOM 1326 C CG . HIS A 1 166 ? -21.178 21.116 -29.356 1.00 49.87 ? 170 HIS A CG 1 ATOM 1327 N ND1 . HIS A 1 166 ? -20.647 19.852 -29.510 1.00 50.06 ? 170 HIS A ND1 1 ATOM 1328 C CD2 . HIS A 1 166 ? -22.248 21.180 -30.185 1.00 49.04 ? 170 HIS A CD2 1 ATOM 1329 C CE1 . HIS A 1 166 ? -21.369 19.181 -30.390 1.00 49.87 ? 170 HIS A CE1 1 ATOM 1330 N NE2 . HIS A 1 166 ? -22.346 19.964 -30.814 1.00 49.06 ? 170 HIS A NE2 1 ATOM 1331 N N . ARG A 1 167 ? -19.445 23.740 -26.390 1.00 49.58 ? 171 ARG A N 1 ATOM 1332 C CA . ARG A 1 167 ? -18.713 24.623 -25.488 1.00 49.50 ? 171 ARG A CA 1 ATOM 1333 C C . ARG A 1 167 ? -19.722 25.498 -24.741 1.00 48.98 ? 171 ARG A C 1 ATOM 1334 O O . ARG A 1 167 ? -19.352 26.335 -23.924 1.00 49.03 ? 171 ARG A O 1 ATOM 1335 C CB . ARG A 1 167 ? -17.710 25.486 -26.266 1.00 49.96 ? 171 ARG A CB 1 ATOM 1336 C CG . ARG A 1 167 ? -16.536 24.715 -26.902 1.00 52.04 ? 171 ARG A CG 1 ATOM 1337 C CD . ARG A 1 167 ? -15.657 24.002 -25.851 1.00 55.28 ? 171 ARG A CD 1 ATOM 1338 N NE . ARG A 1 167 ? -14.602 24.861 -25.298 1.00 57.30 ? 171 ARG A NE 1 ATOM 1339 C CZ . ARG A 1 167 ? -14.070 24.716 -24.082 1.00 58.12 ? 171 ARG A CZ 1 ATOM 1340 N NH1 . ARG A 1 167 ? -13.108 25.543 -23.675 1.00 58.47 ? 171 ARG A NH1 1 ATOM 1341 N NH2 . ARG A 1 167 ? -14.498 23.749 -23.267 1.00 57.25 ? 171 ARG A NH2 1 ATOM 1342 N N . ARG A 1 168 ? -21.003 25.268 -25.027 1.00 48.44 ? 172 ARG A N 1 ATOM 1343 C CA . ARG A 1 168 ? -22.120 26.052 -24.508 1.00 47.90 ? 172 ARG A CA 1 ATOM 1344 C C . ARG A 1 168 ? -22.617 25.455 -23.204 1.00 47.39 ? 172 ARG A C 1 ATOM 1345 O O . ARG A 1 168 ? -23.217 24.386 -23.196 1.00 47.28 ? 172 ARG A O 1 ATOM 1346 C CB . ARG A 1 168 ? -23.254 26.036 -25.533 1.00 47.92 ? 172 ARG A CB 1 ATOM 1347 C CG . ARG A 1 168 ? -24.568 26.654 -25.104 1.00 48.33 ? 172 ARG A CG 1 ATOM 1348 C CD . ARG A 1 168 ? -24.812 27.926 -25.887 1.00 49.88 ? 172 ARG A CD 1 ATOM 1349 N NE . ARG A 1 168 ? -26.185 28.034 -26.386 1.00 51.04 ? 172 ARG A NE 1 ATOM 1350 C CZ . ARG A 1 168 ? -26.561 28.813 -27.400 1.00 51.25 ? 172 ARG A CZ 1 ATOM 1351 N NH1 . ARG A 1 168 ? -25.676 29.566 -28.051 1.00 51.39 ? 172 ARG A NH1 1 ATOM 1352 N NH2 . ARG A 1 168 ? -27.832 28.845 -27.764 1.00 50.98 ? 172 ARG A NH2 1 ATOM 1353 N N . GLY A 1 169 ? -22.355 26.142 -22.101 1.00 46.84 ? 173 GLY A N 1 ATOM 1354 C CA . GLY A 1 169 ? -22.880 25.718 -20.813 1.00 46.05 ? 173 GLY A CA 1 ATOM 1355 C C . GLY A 1 169 ? -24.272 26.276 -20.651 1.00 45.49 ? 173 GLY A C 1 ATOM 1356 O O . GLY A 1 169 ? -24.540 27.402 -21.061 1.00 45.54 ? 173 GLY A O 1 ATOM 1357 N N . LEU A 1 170 ? -25.163 25.490 -20.060 1.00 44.93 ? 174 LEU A N 1 ATOM 1358 C CA . LEU A 1 170 ? -26.535 25.929 -19.873 1.00 44.55 ? 174 LEU A CA 1 ATOM 1359 C C . LEU A 1 170 ? -27.163 25.313 -18.626 1.00 44.48 ? 174 LEU A C 1 ATOM 1360 O O . LEU A 1 170 ? -26.652 24.334 -18.081 1.00 44.53 ? 174 LEU A O 1 ATOM 1361 C CB . LEU A 1 170 ? -27.366 25.657 -21.137 1.00 44.47 ? 174 LEU A CB 1 ATOM 1362 C CG . LEU A 1 170 ? -27.798 24.258 -21.600 1.00 44.30 ? 174 LEU A CG 1 ATOM 1363 C CD1 . LEU A 1 170 ? -28.677 24.395 -22.823 1.00 45.29 ? 174 LEU A CD1 1 ATOM 1364 C CD2 . LEU A 1 170 ? -26.652 23.314 -21.903 1.00 43.75 ? 174 LEU A CD2 1 ATOM 1365 N N . ALA A 1 171 ? -28.249 25.919 -18.156 1.00 44.39 ? 175 ALA A N 1 ATOM 1366 C CA . ALA A 1 171 ? -28.974 25.409 -17.003 1.00 44.30 ? 175 ALA A CA 1 ATOM 1367 C C . ALA A 1 171 ? -30.322 24.908 -17.476 1.00 44.37 ? 175 ALA A C 1 ATOM 1368 O O . ALA A 1 171 ? -31.237 25.700 -17.702 1.00 44.41 ? 175 ALA A O 1 ATOM 1369 C CB . ALA A 1 171 ? -29.138 26.493 -15.949 1.00 44.03 ? 175 ALA A CB 1 ATOM 1370 N N . ILE A 1 172 ? -30.432 23.595 -17.645 1.00 44.52 ? 176 ILE A N 1 ATOM 1371 C CA . ILE A 1 172 ? -31.659 22.995 -18.152 1.00 44.93 ? 176 ILE A CA 1 ATOM 1372 C C . ILE A 1 172 ? -32.745 23.053 -17.074 1.00 45.25 ? 176 ILE A C 1 ATOM 1373 O O . ILE A 1 172 ? -32.558 22.549 -15.973 1.00 45.50 ? 176 ILE A O 1 ATOM 1374 C CB . ILE A 1 172 ? -31.434 21.538 -18.610 1.00 44.78 ? 176 ILE A CB 1 ATOM 1375 C CG1 . ILE A 1 172 ? -30.232 21.442 -19.555 1.00 44.87 ? 176 ILE A CG1 1 ATOM 1376 C CG2 . ILE A 1 172 ? -32.693 20.984 -19.268 1.00 44.92 ? 176 ILE A CG2 1 ATOM 1377 C CD1 . ILE A 1 172 ? -29.783 20.000 -19.837 1.00 45.05 ? 176 ILE A CD1 1 ATOM 1378 N N . THR A 1 173 ? -33.869 23.677 -17.397 1.00 45.67 ? 177 THR A N 1 ATOM 1379 C CA . THR A 1 173 ? -34.957 23.845 -16.445 1.00 46.26 ? 177 THR A CA 1 ATOM 1380 C C . THR A 1 173 ? -35.986 22.740 -16.619 1.00 46.83 ? 177 THR A C 1 ATOM 1381 O O . THR A 1 173 ? -36.354 22.378 -17.745 1.00 47.10 ? 177 THR A O 1 ATOM 1382 C CB . THR A 1 173 ? -35.656 25.215 -16.617 1.00 46.21 ? 177 THR A CB 1 ATOM 1383 O OG1 . THR A 1 173 ? -34.669 26.232 -16.800 1.00 47.14 ? 177 THR A OG1 1 ATOM 1384 C CG2 . THR A 1 173 ? -36.504 25.569 -15.401 1.00 45.83 ? 177 THR A CG2 1 ATOM 1385 N N . TYR A 1 174 ? -36.451 22.208 -15.494 1.00 47.25 ? 178 TYR A N 1 ATOM 1386 C CA . TYR A 1 174 ? -37.523 21.226 -15.492 1.00 47.48 ? 178 TYR A CA 1 ATOM 1387 C C . TYR A 1 174 ? -38.660 21.734 -14.623 1.00 47.81 ? 178 TYR A C 1 ATOM 1388 O O . TYR A 1 174 ? -38.432 22.361 -13.588 1.00 47.76 ? 178 TYR A O 1 ATOM 1389 C CB . TYR A 1 174 ? -37.014 19.887 -14.968 1.00 47.42 ? 178 TYR A CB 1 ATOM 1390 C CG . TYR A 1 174 ? -36.361 18.982 -15.999 1.00 47.21 ? 178 TYR A CG 1 ATOM 1391 C CD1 . TYR A 1 174 ? -35.074 19.244 -16.485 1.00 46.63 ? 178 TYR A CD1 1 ATOM 1392 C CD2 . TYR A 1 174 ? -37.020 17.837 -16.458 1.00 46.32 ? 178 TYR A CD2 1 ATOM 1393 C CE1 . TYR A 1 174 ? -34.467 18.398 -17.412 1.00 46.46 ? 178 TYR A CE1 1 ATOM 1394 C CE2 . TYR A 1 174 ? -36.426 16.987 -17.381 1.00 46.51 ? 178 TYR A CE2 1 ATOM 1395 C CZ . TYR A 1 174 ? -35.152 17.270 -17.855 1.00 47.14 ? 178 TYR A CZ 1 ATOM 1396 O OH . TYR A 1 174 ? -34.572 16.419 -18.768 1.00 46.98 ? 178 TYR A OH 1 ATOM 1397 N N . THR A 1 175 ? -39.885 21.465 -15.057 1.00 48.46 ? 179 THR A N 1 ATOM 1398 C CA . THR A 1 175 ? -41.084 21.921 -14.356 1.00 49.17 ? 179 THR A CA 1 ATOM 1399 C C . THR A 1 175 ? -41.894 20.711 -13.922 1.00 49.64 ? 179 THR A C 1 ATOM 1400 O O . THR A 1 175 ? -41.907 19.695 -14.613 1.00 49.92 ? 179 THR A O 1 ATOM 1401 C CB . THR A 1 175 ? -41.961 22.872 -15.235 1.00 49.40 ? 179 THR A CB 1 ATOM 1402 O OG1 . THR A 1 175 ? -42.026 22.385 -16.589 1.00 49.44 ? 179 THR A OG1 1 ATOM 1403 C CG2 . THR A 1 175 ? -41.388 24.292 -15.241 1.00 48.98 ? 179 THR A CG2 1 ATOM 1404 N N . SER A 1 176 ? -42.551 20.807 -12.773 1.00 50.14 ? 180 SER A N 1 ATOM 1405 C CA . SER A 1 176 ? -43.378 19.711 -12.282 1.00 50.79 ? 180 SER A CA 1 ATOM 1406 C C . SER A 1 176 ? -44.595 20.245 -11.551 1.00 51.39 ? 180 SER A C 1 ATOM 1407 O O . SER A 1 176 ? -44.536 21.316 -10.949 1.00 51.83 ? 180 SER A O 1 ATOM 1408 C CB . SER A 1 176 ? -42.578 18.813 -11.346 1.00 50.67 ? 180 SER A CB 1 ATOM 1409 O OG . SER A 1 176 ? -43.340 17.694 -10.940 1.00 50.81 ? 180 SER A OG 1 ATOM 1410 N N . LYS A 1 177 ? -45.697 19.501 -11.601 1.00 51.86 ? 181 LYS A N 1 ATOM 1411 C CA . LYS A 1 177 ? -46.919 19.909 -10.912 1.00 52.37 ? 181 LYS A CA 1 ATOM 1412 C C . LYS A 1 177 ? -47.020 19.243 -9.557 1.00 52.37 ? 181 LYS A C 1 ATOM 1413 O O . LYS A 1 177 ? -47.743 19.714 -8.686 1.00 52.72 ? 181 LYS A O 1 ATOM 1414 C CB . LYS A 1 177 ? -48.162 19.601 -11.756 1.00 52.15 ? 181 LYS A CB 1 ATOM 1415 C CG . LYS A 1 177 ? -48.295 20.490 -12.986 1.00 52.92 ? 181 LYS A CG 1 ATOM 1416 C CD . LYS A 1 177 ? -49.539 20.177 -13.810 1.00 53.17 ? 181 LYS A CD 1 ATOM 1417 C CE . LYS A 1 177 ? -49.656 21.139 -14.989 1.00 54.76 ? 181 LYS A CE 1 ATOM 1418 N NZ . LYS A 1 177 ? -50.804 20.813 -15.883 1.00 56.03 ? 181 LYS A NZ 1 ATOM 1419 N N . ASP A 1 178 ? -46.267 18.161 -9.379 1.00 52.62 ? 182 ASP A N 1 ATOM 1420 C CA . ASP A 1 178 ? -46.434 17.284 -8.228 1.00 52.71 ? 182 ASP A CA 1 ATOM 1421 C C . ASP A 1 178 ? -45.118 16.807 -7.623 1.00 52.72 ? 182 ASP A C 1 ATOM 1422 O O . ASP A 1 178 ? -45.127 16.090 -6.619 1.00 53.00 ? 182 ASP A O 1 ATOM 1423 C CB . ASP A 1 178 ? -47.297 16.075 -8.620 1.00 52.86 ? 182 ASP A CB 1 ATOM 1424 C CG . ASP A 1 178 ? -46.517 15.013 -9.388 1.00 52.94 ? 182 ASP A CG 1 ATOM 1425 O OD1 . ASP A 1 178 ? -45.846 15.351 -10.388 1.00 52.54 ? 182 ASP A OD1 1 ATOM 1426 O OD2 . ASP A 1 178 ? -46.587 13.832 -8.987 1.00 53.48 ? 182 ASP A OD2 1 ATOM 1427 N N . PHE A 1 179 ? -43.999 17.189 -8.244 1.00 52.56 ? 183 PHE A N 1 ATOM 1428 C CA . PHE A 1 179 ? -42.653 16.835 -7.770 1.00 52.47 ? 183 PHE A CA 1 ATOM 1429 C C . PHE A 1 179 ? -42.357 15.334 -7.960 1.00 52.61 ? 183 PHE A C 1 ATOM 1430 O O . PHE A 1 179 ? -41.541 14.756 -7.233 1.00 52.74 ? 183 PHE A O 1 ATOM 1431 C CB . PHE A 1 179 ? -42.462 17.256 -6.298 1.00 52.18 ? 183 PHE A CB 1 ATOM 1432 C CG . PHE A 1 179 ? -41.084 17.789 -5.973 1.00 52.21 ? 183 PHE A CG 1 ATOM 1433 C CD1 . PHE A 1 179 ? -40.832 19.159 -5.986 1.00 52.38 ? 183 PHE A CD1 1 ATOM 1434 C CD2 . PHE A 1 179 ? -40.045 16.928 -5.624 1.00 52.33 ? 183 PHE A CD2 1 ATOM 1435 C CE1 . PHE A 1 179 ? -39.565 19.662 -5.673 1.00 52.00 ? 183 PHE A CE1 1 ATOM 1436 C CE2 . PHE A 1 179 ? -38.774 17.425 -5.314 1.00 51.98 ? 183 PHE A CE2 1 ATOM 1437 C CZ . PHE A 1 179 ? -38.538 18.793 -5.337 1.00 51.72 ? 183 PHE A CZ 1 ATOM 1438 N N . LEU A 1 180 ? -43.032 14.706 -8.924 1.00 52.54 ? 184 LEU A N 1 ATOM 1439 C CA . LEU A 1 180 ? -42.742 13.316 -9.288 1.00 52.67 ? 184 LEU A CA 1 ATOM 1440 C C . LEU A 1 180 ? -42.631 13.131 -10.800 1.00 52.53 ? 184 LEU A C 1 ATOM 1441 O O . LEU A 1 180 ? -41.887 12.269 -11.272 1.00 52.56 ? 184 LEU A O 1 ATOM 1442 C CB . LEU A 1 180 ? -43.779 12.347 -8.702 1.00 52.99 ? 184 LEU A CB 1 ATOM 1443 C CG . LEU A 1 180 ? -43.868 12.205 -7.174 1.00 53.86 ? 184 LEU A CG 1 ATOM 1444 C CD1 . LEU A 1 180 ? -45.158 11.491 -6.767 1.00 53.79 ? 184 LEU A CD1 1 ATOM 1445 C CD2 . LEU A 1 180 ? -42.631 11.508 -6.573 1.00 54.22 ? 184 LEU A CD2 1 ATOM 1446 N N . LYS A 1 181 ? -43.372 13.944 -11.546 1.00 52.24 ? 185 LYS A N 1 ATOM 1447 C CA . LYS A 1 181 ? -43.346 13.917 -13.003 1.00 52.12 ? 185 LYS A CA 1 ATOM 1448 C C . LYS A 1 181 ? -42.736 15.232 -13.473 1.00 51.61 ? 185 LYS A C 1 ATOM 1449 O O . LYS A 1 181 ? -43.390 16.275 -13.411 1.00 51.76 ? 185 LYS A O 1 ATOM 1450 C CB . LYS A 1 181 ? -44.776 13.781 -13.538 1.00 52.45 ? 185 LYS A CB 1 ATOM 1451 C CG . LYS A 1 181 ? -44.943 12.905 -14.774 1.00 53.85 ? 185 LYS A CG 1 ATOM 1452 C CD . LYS A 1 181 ? -44.920 13.706 -16.076 1.00 55.89 ? 185 LYS A CD 1 ATOM 1453 C CE . LYS A 1 181 ? -45.324 12.821 -17.262 1.00 56.65 ? 185 LYS A CE 1 ATOM 1454 N NZ . LYS A 1 181 ? -44.868 13.367 -18.567 1.00 57.24 ? 185 LYS A NZ 1 ATOM 1455 N N . TRP A 1 182 ? -41.477 15.188 -13.910 1.00 50.90 ? 186 TRP A N 1 ATOM 1456 C CA . TRP A 1 182 ? -40.776 16.398 -14.355 1.00 50.10 ? 186 TRP A CA 1 ATOM 1457 C C . TRP A 1 182 ? -40.667 16.428 -15.867 1.00 50.47 ? 186 TRP A C 1 ATOM 1458 O O . TRP A 1 182 ? -40.287 15.438 -16.485 1.00 50.21 ? 186 TRP A O 1 ATOM 1459 C CB . TRP A 1 182 ? -39.384 16.505 -13.723 1.00 49.05 ? 186 TRP A CB 1 ATOM 1460 C CG . TRP A 1 182 ? -39.410 16.659 -12.244 1.00 47.72 ? 186 TRP A CG 1 ATOM 1461 C CD1 . TRP A 1 182 ? -39.548 15.666 -11.321 1.00 47.06 ? 186 TRP A CD1 1 ATOM 1462 C CD2 . TRP A 1 182 ? -39.298 17.877 -11.508 1.00 46.77 ? 186 TRP A CD2 1 ATOM 1463 N NE1 . TRP A 1 182 ? -39.533 16.188 -10.053 1.00 46.42 ? 186 TRP A NE1 1 ATOM 1464 C CE2 . TRP A 1 182 ? -39.380 17.546 -10.138 1.00 46.52 ? 186 TRP A CE2 1 ATOM 1465 C CE3 . TRP A 1 182 ? -39.140 19.221 -11.871 1.00 46.72 ? 186 TRP A CE3 1 ATOM 1466 C CZ2 . TRP A 1 182 ? -39.307 18.508 -9.126 1.00 46.94 ? 186 TRP A CZ2 1 ATOM 1467 C CZ3 . TRP A 1 182 ? -39.073 20.180 -10.865 1.00 47.01 ? 186 TRP A CZ3 1 ATOM 1468 C CH2 . TRP A 1 182 ? -39.151 19.814 -9.507 1.00 47.24 ? 186 TRP A CH2 1 ATOM 1469 N N . GLU A 1 183 ? -41.016 17.563 -16.463 1.00 51.09 ? 187 GLU A N 1 ATOM 1470 C CA . GLU A 1 183 ? -40.893 17.716 -17.900 1.00 52.09 ? 187 GLU A CA 1 ATOM 1471 C C . GLU A 1 183 ? -39.953 18.868 -18.236 1.00 51.90 ? 187 GLU A C 1 ATOM 1472 O O . GLU A 1 183 ? -40.067 19.968 -17.684 1.00 51.88 ? 187 GLU A O 1 ATOM 1473 C CB . GLU A 1 183 ? -42.264 17.883 -18.561 1.00 52.08 ? 187 GLU A CB 1 ATOM 1474 C CG . GLU A 1 183 ? -42.346 17.250 -19.963 1.00 53.77 ? 187 GLU A CG 1 ATOM 1475 C CD . GLU A 1 183 ? -43.628 17.609 -20.726 1.00 53.85 ? 187 GLU A CD 1 ATOM 1476 O OE1 . GLU A 1 183 ? -43.530 18.091 -21.886 1.00 55.22 ? 187 GLU A OE1 1 ATOM 1477 O OE2 . GLU A 1 183 ? -44.732 17.412 -20.164 1.00 56.42 ? 187 GLU A OE2 1 ATOM 1478 N N . LYS A 1 184 ? -39.013 18.583 -19.136 1.00 52.01 ? 188 LYS A N 1 ATOM 1479 C CA . LYS A 1 184 ? -37.975 19.517 -19.549 1.00 52.03 ? 188 LYS A CA 1 ATOM 1480 C C . LYS A 1 184 ? -38.570 20.723 -20.264 1.00 51.95 ? 188 LYS A C 1 ATOM 1481 O O . LYS A 1 184 ? -39.271 20.560 -21.255 1.00 52.03 ? 188 LYS A O 1 ATOM 1482 C CB . LYS A 1 184 ? -36.994 18.798 -20.476 1.00 51.96 ? 188 LYS A CB 1 ATOM 1483 C CG . LYS A 1 184 ? -35.846 19.652 -21.002 1.00 52.86 ? 188 LYS A CG 1 ATOM 1484 C CD . LYS A 1 184 ? -35.141 18.948 -22.156 1.00 54.54 ? 188 LYS A CD 1 ATOM 1485 C CE . LYS A 1 184 ? -34.003 19.777 -22.732 1.00 55.81 ? 188 LYS A CE 1 ATOM 1486 N NZ . LYS A 1 184 ? -34.488 20.993 -23.454 1.00 56.51 ? 188 LYS A NZ 1 ATOM 1487 N N . SER A 1 185 ? -38.294 21.926 -19.764 1.00 51.84 ? 189 SER A N 1 ATOM 1488 C CA . SER A 1 185 ? -38.661 23.141 -20.483 1.00 51.93 ? 189 SER A CA 1 ATOM 1489 C C . SER A 1 185 ? -37.896 23.221 -21.799 1.00 51.92 ? 189 SER A C 1 ATOM 1490 O O . SER A 1 185 ? -36.726 22.841 -21.855 1.00 52.02 ? 189 SER A O 1 ATOM 1491 C CB . SER A 1 185 ? -38.363 24.378 -19.646 1.00 51.88 ? 189 SER A CB 1 ATOM 1492 O OG . SER A 1 185 ? -39.247 24.462 -18.548 1.00 52.77 ? 189 SER A OG 1 ATOM 1493 N N . PRO A 1 186 ? -38.548 23.721 -22.869 1.00 51.96 ? 190 PRO A N 1 ATOM 1494 C CA . PRO A 1 186 ? -37.836 23.801 -24.154 1.00 51.80 ? 190 PRO A CA 1 ATOM 1495 C C . PRO A 1 186 ? -36.617 24.714 -24.049 1.00 51.57 ? 190 PRO A C 1 ATOM 1496 O O . PRO A 1 186 ? -35.631 24.531 -24.763 1.00 51.54 ? 190 PRO A O 1 ATOM 1497 C CB . PRO A 1 186 ? -38.884 24.402 -25.109 1.00 51.75 ? 190 PRO A CB 1 ATOM 1498 C CG . PRO A 1 186 ? -39.908 25.038 -24.234 1.00 51.64 ? 190 PRO A CG 1 ATOM 1499 C CD . PRO A 1 186 ? -39.927 24.241 -22.965 1.00 51.93 ? 190 PRO A CD 1 ATOM 1500 N N . GLU A 1 187 ? -36.693 25.662 -23.122 1.00 51.33 ? 191 GLU A N 1 ATOM 1501 C CA . GLU A 1 187 ? -35.700 26.700 -22.985 1.00 51.02 ? 191 GLU A CA 1 ATOM 1502 C C . GLU A 1 187 ? -34.869 26.546 -21.714 1.00 50.20 ? 191 GLU A C 1 ATOM 1503 O O . GLU A 1 187 ? -35.409 26.241 -20.650 1.00 50.39 ? 191 GLU A O 1 ATOM 1504 C CB . GLU A 1 187 ? -36.406 28.055 -22.970 1.00 51.67 ? 191 GLU A CB 1 ATOM 1505 C CG . GLU A 1 187 ? -37.176 28.391 -24.251 1.00 53.18 ? 191 GLU A CG 1 ATOM 1506 C CD . GLU A 1 187 ? -36.257 28.779 -25.401 1.00 54.85 ? 191 GLU A CD 1 ATOM 1507 O OE1 . GLU A 1 187 ? -35.309 28.015 -25.692 1.00 55.13 ? 191 GLU A OE1 1 ATOM 1508 O OE2 . GLU A 1 187 ? -36.488 29.846 -26.014 1.00 55.55 ? 191 GLU A OE2 1 ATOM 1509 N N . PRO A 1 188 ? -33.547 26.753 -21.824 1.00 49.24 ? 192 PRO A N 1 ATOM 1510 C CA . PRO A 1 188 ? -32.667 26.934 -20.668 1.00 48.45 ? 192 PRO A CA 1 ATOM 1511 C C . PRO A 1 188 ? -33.014 28.201 -19.897 1.00 47.83 ? 192 PRO A C 1 ATOM 1512 O O . PRO A 1 188 ? -33.464 29.185 -20.487 1.00 47.72 ? 192 PRO A O 1 ATOM 1513 C CB . PRO A 1 188 ? -31.280 27.099 -21.300 1.00 48.47 ? 192 PRO A CB 1 ATOM 1514 C CG . PRO A 1 188 ? -31.398 26.562 -22.665 1.00 48.84 ? 192 PRO A CG 1 ATOM 1515 C CD . PRO A 1 188 ? -32.807 26.798 -23.094 1.00 49.17 ? 192 PRO A CD 1 ATOM 1516 N N . LEU A 1 189 ? -32.805 28.182 -18.586 1.00 47.38 ? 193 LEU A N 1 ATOM 1517 C CA . LEU A 1 189 ? -33.015 29.379 -17.773 1.00 47.03 ? 193 LEU A CA 1 ATOM 1518 C C . LEU A 1 189 ? -31.988 30.425 -18.190 1.00 46.90 ? 193 LEU A C 1 ATOM 1519 O O . LEU A 1 189 ? -32.276 31.619 -18.207 1.00 46.68 ? 193 LEU A O 1 ATOM 1520 C CB . LEU A 1 189 ? -32.891 29.057 -16.278 1.00 46.89 ? 193 LEU A CB 1 ATOM 1521 C CG . LEU A 1 189 ? -33.165 30.154 -15.239 1.00 46.86 ? 193 LEU A CG 1 ATOM 1522 C CD1 . LEU A 1 189 ? -34.651 30.300 -14.991 1.00 46.30 ? 193 LEU A CD1 1 ATOM 1523 C CD2 . LEU A 1 189 ? -32.460 29.848 -13.936 1.00 46.57 ? 193 LEU A CD2 1 ATOM 1524 N N . HIS A 1 190 ? -30.791 29.948 -18.522 1.00 46.93 ? 194 HIS A N 1 ATOM 1525 C CA . HIS A 1 190 ? -29.704 30.778 -19.025 1.00 47.39 ? 194 HIS A CA 1 ATOM 1526 C C . HIS A 1 190 ? -28.646 29.894 -19.685 1.00 47.42 ? 194 HIS A C 1 ATOM 1527 O O . HIS A 1 190 ? -28.597 28.680 -19.452 1.00 47.45 ? 194 HIS A O 1 ATOM 1528 C CB . HIS A 1 190 ? -29.078 31.607 -17.896 1.00 47.52 ? 194 HIS A CB 1 ATOM 1529 C CG . HIS A 1 190 ? -28.310 32.799 -18.377 1.00 48.40 ? 194 HIS A CG 1 ATOM 1530 N ND1 . HIS A 1 190 ? -28.903 33.842 -19.056 1.00 49.20 ? 194 HIS A ND1 1 ATOM 1531 C CD2 . HIS A 1 190 ? -26.999 33.121 -18.263 1.00 49.28 ? 194 HIS A CD2 1 ATOM 1532 C CE1 . HIS A 1 190 ? -27.988 34.751 -19.349 1.00 49.35 ? 194 HIS A CE1 1 ATOM 1533 N NE2 . HIS A 1 190 ? -26.825 34.340 -18.877 1.00 49.39 ? 194 HIS A NE2 1 ATOM 1534 N N . TYR A 1 191 ? -27.817 30.503 -20.524 1.00 47.41 ? 195 TYR A N 1 ATOM 1535 C CA . TYR A 1 191 ? -26.700 29.811 -21.154 1.00 47.64 ? 195 TYR A CA 1 ATOM 1536 C C . TYR A 1 191 ? -25.607 30.826 -21.470 1.00 47.96 ? 195 TYR A C 1 ATOM 1537 O O . TYR A 1 191 ? -25.885 32.016 -21.669 1.00 48.21 ? 195 TYR A O 1 ATOM 1538 C CB . TYR A 1 191 ? -27.136 29.091 -22.439 1.00 47.54 ? 195 TYR A CB 1 ATOM 1539 C CG . TYR A 1 191 ? -27.613 30.022 -23.542 1.00 47.70 ? 195 TYR A CG 1 ATOM 1540 C CD1 . TYR A 1 191 ? -26.721 30.559 -24.476 1.00 47.45 ? 195 TYR A CD1 1 ATOM 1541 C CD2 . TYR A 1 191 ? -28.956 30.375 -23.642 1.00 47.89 ? 195 TYR A CD2 1 ATOM 1542 C CE1 . TYR A 1 191 ? -27.158 31.412 -25.476 1.00 47.40 ? 195 TYR A CE1 1 ATOM 1543 C CE2 . TYR A 1 191 ? -29.404 31.226 -24.637 1.00 47.81 ? 195 TYR A CE2 1 ATOM 1544 C CZ . TYR A 1 191 ? -28.506 31.737 -25.549 1.00 47.97 ? 195 TYR A CZ 1 ATOM 1545 O OH . TYR A 1 191 ? -28.973 32.582 -26.528 1.00 48.30 ? 195 TYR A OH 1 ATOM 1546 N N . ASP A 1 192 ? -24.369 30.350 -21.513 1.00 48.08 ? 196 ASP A N 1 ATOM 1547 C CA . ASP A 1 192 ? -23.239 31.170 -21.925 1.00 48.26 ? 196 ASP A CA 1 ATOM 1548 C C . ASP A 1 192 ? -22.370 30.371 -22.894 1.00 48.40 ? 196 ASP A C 1 ATOM 1549 O O . ASP A 1 192 ? -21.986 29.228 -22.608 1.00 48.70 ? 196 ASP A O 1 ATOM 1550 C CB . ASP A 1 192 ? -22.451 31.677 -20.704 1.00 48.17 ? 196 ASP A CB 1 ATOM 1551 C CG . ASP A 1 192 ? -23.195 32.792 -19.947 1.00 48.64 ? 196 ASP A CG 1 ATOM 1552 O OD1 . ASP A 1 192 ? -23.429 33.868 -20.543 1.00 48.85 ? 196 ASP A OD1 1 ATOM 1553 O OD2 . ASP A 1 192 ? -23.554 32.606 -18.756 1.00 48.60 ? 196 ASP A OD2 1 ATOM 1554 N N . ASP A 1 193 ? -22.106 30.964 -24.059 1.00 48.25 ? 197 ASP A N 1 ATOM 1555 C CA . ASP A 1 193 ? -21.286 30.338 -25.094 1.00 48.10 ? 197 ASP A CA 1 ATOM 1556 C C . ASP A 1 193 ? -19.803 30.322 -24.721 1.00 48.03 ? 197 ASP A C 1 ATOM 1557 O O . ASP A 1 193 ? -19.273 31.312 -24.217 1.00 48.15 ? 197 ASP A O 1 ATOM 1558 C CB . ASP A 1 193 ? -21.502 31.040 -26.444 1.00 48.02 ? 197 ASP A CB 1 ATOM 1559 C CG . ASP A 1 193 ? -22.564 30.356 -27.295 1.00 48.18 ? 197 ASP A CG 1 ATOM 1560 O OD1 . ASP A 1 193 ? -23.502 31.039 -27.770 1.00 47.76 ? 197 ASP A OD1 1 ATOM 1561 O OD2 . ASP A 1 193 ? -22.457 29.123 -27.487 1.00 48.07 ? 197 ASP A OD2 1 ATOM 1562 N N . GLY A 1 194 ? -19.146 29.188 -24.953 1.00 47.94 ? 198 GLY A N 1 ATOM 1563 C CA . GLY A 1 194 ? -17.702 29.066 -24.741 1.00 47.82 ? 198 GLY A CA 1 ATOM 1564 C C . GLY A 1 194 ? -17.254 28.972 -23.291 1.00 47.81 ? 198 GLY A C 1 ATOM 1565 O O . GLY A 1 194 ? -16.064 29.109 -23.000 1.00 48.22 ? 198 GLY A O 1 ATOM 1566 N N . SER A 1 195 ? -18.202 28.751 -22.382 1.00 47.44 ? 199 SER A N 1 ATOM 1567 C CA . SER A 1 195 ? -17.902 28.590 -20.963 1.00 47.06 ? 199 SER A CA 1 ATOM 1568 C C . SER A 1 195 ? -17.517 27.151 -20.635 1.00 46.71 ? 199 SER A C 1 ATOM 1569 O O . SER A 1 195 ? -16.621 26.919 -19.833 1.00 47.09 ? 199 SER A O 1 ATOM 1570 C CB . SER A 1 195 ? -19.105 28.992 -20.117 1.00 47.16 ? 199 SER A CB 1 ATOM 1571 O OG . SER A 1 195 ? -20.116 28.006 -20.204 1.00 47.36 ? 199 SER A OG 1 ATOM 1572 N N . GLY A 1 196 ? -18.195 26.190 -21.255 1.00 46.11 ? 200 GLY A N 1 ATOM 1573 C CA . GLY A 1 196 ? -17.983 24.783 -20.938 1.00 45.34 ? 200 GLY A CA 1 ATOM 1574 C C . GLY A 1 196 ? -19.009 24.322 -19.921 1.00 44.99 ? 200 GLY A C 1 ATOM 1575 O O . GLY A 1 196 ? -20.025 24.989 -19.708 1.00 45.02 ? 200 GLY A O 1 ATOM 1576 N N . MET A 1 197 ? -18.742 23.187 -19.285 1.00 44.37 ? 201 MET A N 1 ATOM 1577 C CA . MET A 1 197 ? -19.696 22.565 -18.370 1.00 43.94 ? 201 MET A CA 1 ATOM 1578 C C . MET A 1 197 ? -20.059 23.459 -17.177 1.00 43.55 ? 201 MET A C 1 ATOM 1579 O O . MET A 1 197 ? -19.169 24.012 -16.513 1.00 43.78 ? 201 MET A O 1 ATOM 1580 C CB . MET A 1 197 ? -19.142 21.225 -17.873 1.00 44.21 ? 201 MET A CB 1 ATOM 1581 C CG . MET A 1 197 ? -20.017 20.510 -16.863 1.00 44.44 ? 201 MET A CG 1 ATOM 1582 S SD . MET A 1 197 ? -21.526 19.903 -17.616 1.00 45.97 ? 201 MET A SD 1 ATOM 1583 C CE . MET A 1 197 ? -22.445 19.530 -16.134 1.00 45.14 ? 201 MET A CE 1 ATOM 1584 N N . TRP A 1 198 ? -21.365 23.589 -16.925 1.00 42.42 ? 202 TRP A N 1 ATOM 1585 C CA . TRP A 1 198 ? -21.901 24.251 -15.735 1.00 41.30 ? 202 TRP A CA 1 ATOM 1586 C C . TRP A 1 198 ? -22.151 23.219 -14.624 1.00 40.98 ? 202 TRP A C 1 ATOM 1587 O O . TRP A 1 198 ? -23.084 22.423 -14.703 1.00 40.74 ? 202 TRP A O 1 ATOM 1588 C CB . TRP A 1 198 ? -23.218 24.945 -16.083 1.00 40.85 ? 202 TRP A CB 1 ATOM 1589 C CG . TRP A 1 198 ? -23.076 26.276 -16.779 1.00 40.39 ? 202 TRP A CG 1 ATOM 1590 C CD1 . TRP A 1 198 ? -21.953 26.790 -17.362 1.00 39.37 ? 202 TRP A CD1 1 ATOM 1591 C CD2 . TRP A 1 198 ? -24.115 27.241 -16.995 1.00 39.44 ? 202 TRP A CD2 1 ATOM 1592 N NE1 . TRP A 1 198 ? -22.222 28.021 -17.902 1.00 38.80 ? 202 TRP A NE1 1 ATOM 1593 C CE2 . TRP A 1 198 ? -23.541 28.323 -17.691 1.00 39.02 ? 202 TRP A CE2 1 ATOM 1594 C CE3 . TRP A 1 198 ? -25.473 27.299 -16.656 1.00 39.50 ? 202 TRP A CE3 1 ATOM 1595 C CZ2 . TRP A 1 198 ? -24.278 29.454 -18.059 1.00 39.74 ? 202 TRP A CZ2 1 ATOM 1596 C CZ3 . TRP A 1 198 ? -26.209 28.427 -17.023 1.00 39.58 ? 202 TRP A CZ3 1 ATOM 1597 C CH2 . TRP A 1 198 ? -25.607 29.487 -17.715 1.00 39.85 ? 202 TRP A CH2 1 ATOM 1598 N N . GLU A 1 199 ? -21.311 23.232 -13.595 1.00 40.45 ? 203 GLU A N 1 ATOM 1599 C CA . GLU A 1 199 ? -21.481 22.336 -12.450 1.00 39.81 ? 203 GLU A CA 1 ATOM 1600 C C . GLU A 1 199 ? -22.106 23.103 -11.295 1.00 39.37 ? 203 GLU A C 1 ATOM 1601 O O . GLU A 1 199 ? -22.064 24.336 -11.263 1.00 39.01 ? 203 GLU A O 1 ATOM 1602 C CB . GLU A 1 199 ? -20.145 21.726 -12.005 1.00 39.55 ? 203 GLU A CB 1 ATOM 1603 C CG . GLU A 1 199 ? -19.337 21.081 -13.110 1.00 39.56 ? 203 GLU A CG 1 ATOM 1604 C CD . GLU A 1 199 ? -18.113 20.328 -12.602 1.00 40.13 ? 203 GLU A CD 1 ATOM 1605 O OE1 . GLU A 1 199 ? -17.774 19.289 -13.212 1.00 40.67 ? 203 GLU A OE1 1 ATOM 1606 O OE2 . GLU A 1 199 ? -17.490 20.756 -11.602 1.00 40.39 ? 203 GLU A OE2 1 ATOM 1607 N N . CYS A 1 200 ? -22.685 22.359 -10.356 1.00 39.05 ? 204 CYS A N 1 ATOM 1608 C CA . CYS A 1 200 ? -23.274 22.917 -9.132 1.00 39.11 ? 204 CYS A CA 1 ATOM 1609 C C . CYS A 1 200 ? -23.995 24.235 -9.342 1.00 38.22 ? 204 CYS A C 1 ATOM 1610 O O . CYS A 1 200 ? -23.637 25.236 -8.731 1.00 38.12 ? 204 CYS A O 1 ATOM 1611 C CB . CYS A 1 200 ? -22.216 23.094 -8.047 1.00 39.15 ? 204 CYS A CB 1 ATOM 1612 S SG . CYS A 1 200 ? -21.363 21.590 -7.664 1.00 42.33 ? 204 CYS A SG 1 ATOM 1613 N N . PRO A 1 201 ? -25.017 24.241 -10.208 1.00 37.71 ? 205 PRO A N 1 ATOM 1614 C CA . PRO A 1 201 ? -25.788 25.466 -10.321 1.00 37.25 ? 205 PRO A CA 1 ATOM 1615 C C . PRO A 1 201 ? -26.540 25.735 -9.019 1.00 36.85 ? 205 PRO A C 1 ATOM 1616 O O . PRO A 1 201 ? -26.895 24.788 -8.308 1.00 36.79 ? 205 PRO A O 1 ATOM 1617 C CB . PRO A 1 201 ? -26.770 25.158 -11.448 1.00 37.24 ? 205 PRO A CB 1 ATOM 1618 C CG . PRO A 1 201 ? -26.888 23.667 -11.449 1.00 37.76 ? 205 PRO A CG 1 ATOM 1619 C CD . PRO A 1 201 ? -25.527 23.173 -11.088 1.00 37.62 ? 205 PRO A CD 1 ATOM 1620 N N . ASP A 1 202 ? -26.749 27.016 -8.717 1.00 36.28 ? 206 ASP A N 1 ATOM 1621 C CA . ASP A 1 202 ? -27.531 27.469 -7.567 1.00 35.46 ? 206 ASP A CA 1 ATOM 1622 C C . ASP A 1 202 ? -28.388 28.651 -8.023 1.00 35.30 ? 206 ASP A C 1 ATOM 1623 O O . ASP A 1 202 ? -27.955 29.444 -8.848 1.00 35.25 ? 206 ASP A O 1 ATOM 1624 C CB . ASP A 1 202 ? -26.593 27.891 -6.433 1.00 35.20 ? 206 ASP A CB 1 ATOM 1625 C CG . ASP A 1 202 ? -27.263 27.864 -5.068 1.00 34.05 ? 206 ASP A CG 1 ATOM 1626 O OD1 . ASP A 1 202 ? -28.439 27.483 -4.988 1.00 33.50 ? 206 ASP A OD1 1 ATOM 1627 O OD2 . ASP A 1 202 ? -26.609 28.212 -4.063 1.00 32.56 ? 206 ASP A OD2 1 ATOM 1628 N N . PHE A 1 203 ? -29.606 28.764 -7.514 1.00 35.25 ? 207 PHE A N 1 ATOM 1629 C CA . PHE A 1 203 ? -30.505 29.828 -7.961 1.00 35.50 ? 207 PHE A CA 1 ATOM 1630 C C . PHE A 1 203 ? -31.439 30.195 -6.832 1.00 35.90 ? 207 PHE A C 1 ATOM 1631 O O . PHE A 1 203 ? -32.250 29.379 -6.397 1.00 36.30 ? 207 PHE A O 1 ATOM 1632 C CB . PHE A 1 203 ? -31.286 29.405 -9.215 1.00 35.18 ? 207 PHE A CB 1 ATOM 1633 C CG . PHE A 1 203 ? -32.134 30.498 -9.821 1.00 34.94 ? 207 PHE A CG 1 ATOM 1634 C CD1 . PHE A 1 203 ? -31.545 31.566 -10.515 1.00 34.58 ? 207 PHE A CD1 1 ATOM 1635 C CD2 . PHE A 1 203 ? -33.528 30.444 -9.733 1.00 34.41 ? 207 PHE A CD2 1 ATOM 1636 C CE1 . PHE A 1 203 ? -32.331 32.573 -11.094 1.00 34.08 ? 207 PHE A CE1 1 ATOM 1637 C CE2 . PHE A 1 203 ? -34.330 31.447 -10.308 1.00 34.07 ? 207 PHE A CE2 1 ATOM 1638 C CZ . PHE A 1 203 ? -33.729 32.513 -10.991 1.00 34.28 ? 207 PHE A CZ 1 ATOM 1639 N N . PHE A 1 204 ? -31.308 31.429 -6.363 1.00 36.36 ? 208 PHE A N 1 ATOM 1640 C CA . PHE A 1 204 ? -31.990 31.897 -5.167 1.00 36.94 ? 208 PHE A CA 1 ATOM 1641 C C . PHE A 1 204 ? -32.271 33.413 -5.214 1.00 37.64 ? 208 PHE A C 1 ATOM 1642 O O . PHE A 1 204 ? -31.474 34.187 -5.756 1.00 37.40 ? 208 PHE A O 1 ATOM 1643 C CB . PHE A 1 204 ? -31.172 31.533 -3.918 1.00 36.44 ? 208 PHE A CB 1 ATOM 1644 C CG . PHE A 1 204 ? -29.743 32.008 -3.961 1.00 36.57 ? 208 PHE A CG 1 ATOM 1645 C CD1 . PHE A 1 204 ? -29.389 33.250 -3.443 1.00 35.27 ? 208 PHE A CD1 1 ATOM 1646 C CD2 . PHE A 1 204 ? -28.743 31.211 -4.525 1.00 36.39 ? 208 PHE A CD2 1 ATOM 1647 C CE1 . PHE A 1 204 ? -28.063 33.690 -3.483 1.00 35.00 ? 208 PHE A CE1 1 ATOM 1648 C CE2 . PHE A 1 204 ? -27.412 31.652 -4.568 1.00 35.74 ? 208 PHE A CE2 1 ATOM 1649 C CZ . PHE A 1 204 ? -27.076 32.890 -4.042 1.00 35.02 ? 208 PHE A CZ 1 ATOM 1650 N N . PRO A 1 205 ? -33.421 33.835 -4.662 1.00 38.48 ? 209 PRO A N 1 ATOM 1651 C CA . PRO A 1 205 ? -33.706 35.252 -4.534 1.00 39.43 ? 209 PRO A CA 1 ATOM 1652 C C . PRO A 1 205 ? -32.899 35.871 -3.407 1.00 40.50 ? 209 PRO A C 1 ATOM 1653 O O . PRO A 1 205 ? -32.457 35.173 -2.480 1.00 40.56 ? 209 PRO A O 1 ATOM 1654 C CB . PRO A 1 205 ? -35.184 35.274 -4.161 1.00 39.29 ? 209 PRO A CB 1 ATOM 1655 C CG . PRO A 1 205 ? -35.397 34.008 -3.446 1.00 38.75 ? 209 PRO A CG 1 ATOM 1656 C CD . PRO A 1 205 ? -34.524 33.013 -4.138 1.00 38.44 ? 209 PRO A CD 1 ATOM 1657 N N . VAL A 1 206 ? -32.730 37.183 -3.492 1.00 41.49 ? 210 VAL A N 1 ATOM 1658 C CA . VAL A 1 206 ? -31.972 37.929 -2.507 1.00 42.41 ? 210 VAL A CA 1 ATOM 1659 C C . VAL A 1 206 ? -32.614 39.319 -2.367 1.00 43.23 ? 210 VAL A C 1 ATOM 1660 O O . VAL A 1 206 ? -33.140 39.873 -3.341 1.00 43.22 ? 210 VAL A O 1 ATOM 1661 C CB . VAL A 1 206 ? -30.453 37.940 -2.885 1.00 42.16 ? 210 VAL A CB 1 ATOM 1662 C CG1 . VAL A 1 206 ? -30.072 39.135 -3.768 1.00 41.59 ? 210 VAL A CG1 1 ATOM 1663 C CG2 . VAL A 1 206 ? -29.605 37.876 -1.642 1.00 42.82 ? 210 VAL A CG2 1 ATOM 1664 N N . THR A 1 207 ? -32.616 39.862 -1.155 1.00 44.35 ? 211 THR A N 1 ATOM 1665 C CA . THR A 1 207 ? -33.298 41.136 -0.908 1.00 45.62 ? 211 THR A CA 1 ATOM 1666 C C . THR A 1 207 ? -32.446 42.324 -1.379 1.00 46.69 ? 211 THR A C 1 ATOM 1667 O O . THR A 1 207 ? -31.214 42.293 -1.279 1.00 46.95 ? 211 THR A O 1 ATOM 1668 C CB . THR A 1 207 ? -33.761 41.278 0.571 1.00 45.34 ? 211 THR A CB 1 ATOM 1669 O OG1 . THR A 1 207 ? -34.858 42.187 0.640 1.00 45.83 ? 211 THR A OG1 1 ATOM 1670 C CG2 . THR A 1 207 ? -32.647 41.760 1.477 1.00 45.06 ? 211 THR A CG2 1 ATOM 1671 N N . ARG A 1 208 ? -33.108 43.351 -1.909 1.00 47.95 ? 212 ARG A N 1 ATOM 1672 C CA . ARG A 1 208 ? -32.412 44.497 -2.508 1.00 49.04 ? 212 ARG A CA 1 ATOM 1673 C C . ARG A 1 208 ? -31.763 45.395 -1.447 1.00 49.44 ? 212 ARG A C 1 ATOM 1674 O O . ARG A 1 208 ? -30.682 45.950 -1.672 1.00 49.65 ? 212 ARG A O 1 ATOM 1675 C CB . ARG A 1 208 ? -33.347 45.285 -3.446 1.00 49.05 ? 212 ARG A CB 1 ATOM 1676 C CG . ARG A 1 208 ? -32.819 46.647 -3.924 1.00 50.84 ? 212 ARG A CG 1 ATOM 1677 C CD . ARG A 1 208 ? -31.594 46.565 -4.860 1.00 53.95 ? 212 ARG A CD 1 ATOM 1678 N NE . ARG A 1 208 ? -30.636 47.663 -4.640 1.00 55.26 ? 212 ARG A NE 1 ATOM 1679 C CZ . ARG A 1 208 ? -29.896 48.226 -5.595 1.00 55.85 ? 212 ARG A CZ 1 ATOM 1680 N NH1 . ARG A 1 208 ? -29.998 47.820 -6.859 1.00 56.34 ? 212 ARG A NH1 1 ATOM 1681 N NH2 . ARG A 1 208 ? -29.059 49.210 -5.295 1.00 55.78 ? 212 ARG A NH2 1 ATOM 1682 N N . PHE A 1 209 ? -32.416 45.518 -0.293 1.00 49.91 ? 213 PHE A N 1 ATOM 1683 C CA . PHE A 1 209 ? -31.893 46.310 0.820 1.00 50.23 ? 213 PHE A CA 1 ATOM 1684 C C . PHE A 1 209 ? -32.131 45.564 2.115 1.00 50.04 ? 213 PHE A C 1 ATOM 1685 O O . PHE A 1 209 ? -33.270 45.466 2.583 1.00 50.29 ? 213 PHE A O 1 ATOM 1686 C CB . PHE A 1 209 ? -32.556 47.694 0.880 1.00 50.59 ? 213 PHE A CB 1 ATOM 1687 C CG . PHE A 1 209 ? -32.370 48.519 -0.369 1.00 51.59 ? 213 PHE A CG 1 ATOM 1688 C CD1 . PHE A 1 209 ? -33.456 48.803 -1.198 1.00 52.30 ? 213 PHE A CD1 1 ATOM 1689 C CD2 . PHE A 1 209 ? -31.109 49.015 -0.719 1.00 52.75 ? 213 PHE A CD2 1 ATOM 1690 C CE1 . PHE A 1 209 ? -33.290 49.569 -2.362 1.00 53.11 ? 213 PHE A CE1 1 ATOM 1691 C CE2 . PHE A 1 209 ? -30.927 49.776 -1.883 1.00 53.09 ? 213 PHE A CE2 1 ATOM 1692 C CZ . PHE A 1 209 ? -32.020 50.055 -2.705 1.00 52.75 ? 213 PHE A CZ 1 ATOM 1693 N N . GLY A 1 210 ? -31.054 45.037 2.689 1.00 49.66 ? 214 GLY A N 1 ATOM 1694 C CA . GLY A 1 210 ? -31.138 44.255 3.917 1.00 49.56 ? 214 GLY A CA 1 ATOM 1695 C C . GLY A 1 210 ? -30.122 43.139 3.924 1.00 49.43 ? 214 GLY A C 1 ATOM 1696 O O . GLY A 1 210 ? -29.627 42.733 2.869 1.00 49.46 ? 214 GLY A O 1 ATOM 1697 N N . SER A 1 211 ? -29.807 42.648 5.118 1.00 49.46 ? 215 SER A N 1 ATOM 1698 C CA . SER A 1 211 ? -28.817 41.585 5.281 1.00 49.71 ? 215 SER A CA 1 ATOM 1699 C C . SER A 1 211 ? -29.490 40.205 5.378 1.00 49.95 ? 215 SER A C 1 ATOM 1700 O O . SER A 1 211 ? -28.828 39.168 5.289 1.00 50.03 ? 215 SER A O 1 ATOM 1701 C CB . SER A 1 211 ? -27.954 41.847 6.517 1.00 49.58 ? 215 SER A CB 1 ATOM 1702 O OG . SER A 1 211 ? -28.602 41.384 7.692 1.00 49.71 ? 215 SER A OG 1 ATOM 1703 N N . ASN A 1 212 ? -30.809 40.204 5.547 1.00 50.04 ? 216 ASN A N 1 ATOM 1704 C CA . ASN A 1 212 ? -31.541 38.974 5.771 1.00 50.14 ? 216 ASN A CA 1 ATOM 1705 C C . ASN A 1 212 ? -31.803 38.185 4.504 1.00 50.10 ? 216 ASN A C 1 ATOM 1706 O O . ASN A 1 212 ? -31.985 38.757 3.431 1.00 50.02 ? 216 ASN A O 1 ATOM 1707 C CB . ASN A 1 212 ? -32.820 39.242 6.562 1.00 50.23 ? 216 ASN A CB 1 ATOM 1708 C CG . ASN A 1 212 ? -32.536 39.512 8.042 1.00 51.23 ? 216 ASN A CG 1 ATOM 1709 O OD1 . ASN A 1 212 ? -31.497 39.099 8.582 1.00 52.15 ? 216 ASN A OD1 1 ATOM 1710 N ND2 . ASN A 1 212 ? -33.449 40.213 8.700 1.00 51.10 ? 216 ASN A ND2 1 ATOM 1711 N N . GLY A 1 213 ? -31.784 36.863 4.643 1.00 49.99 ? 217 GLY A N 1 ATOM 1712 C CA . GLY A 1 213 ? -31.978 35.963 3.521 1.00 50.18 ? 217 GLY A CA 1 ATOM 1713 C C . GLY A 1 213 ? -33.430 35.901 3.110 1.00 50.33 ? 217 GLY A C 1 ATOM 1714 O O . GLY A 1 213 ? -34.307 36.317 3.869 1.00 50.64 ? 217 GLY A O 1 ATOM 1715 N N . VAL A 1 214 ? -33.682 35.383 1.908 1.00 50.39 ? 218 VAL A N 1 ATOM 1716 C CA . VAL A 1 214 ? -35.035 35.270 1.379 1.00 50.51 ? 218 VAL A CA 1 ATOM 1717 C C . VAL A 1 214 ? -35.383 33.821 1.099 1.00 50.77 ? 218 VAL A C 1 ATOM 1718 O O . VAL A 1 214 ? -34.608 33.108 0.468 1.00 50.93 ? 218 VAL A O 1 ATOM 1719 C CB . VAL A 1 214 ? -35.216 36.088 0.082 1.00 50.51 ? 218 VAL A CB 1 ATOM 1720 C CG1 . VAL A 1 214 ? -36.673 36.097 -0.340 1.00 50.46 ? 218 VAL A CG1 1 ATOM 1721 C CG2 . VAL A 1 214 ? -34.730 37.519 0.272 1.00 50.51 ? 218 VAL A CG2 1 ATOM 1722 N N . GLU A 1 215 ? -36.552 33.394 1.575 1.00 51.14 ? 219 GLU A N 1 ATOM 1723 C CA . GLU A 1 215 ? -37.109 32.088 1.247 1.00 51.41 ? 219 GLU A CA 1 ATOM 1724 C C . GLU A 1 215 ? -37.008 31.895 -0.266 1.00 51.53 ? 219 GLU A C 1 ATOM 1725 O O . GLU A 1 215 ? -37.370 32.787 -1.021 1.00 51.60 ? 219 GLU A O 1 ATOM 1726 C CB . GLU A 1 215 ? -38.572 32.023 1.698 1.00 51.40 ? 219 GLU A CB 1 ATOM 1727 C CG . GLU A 1 215 ? -39.079 30.625 2.062 1.00 52.01 ? 219 GLU A CG 1 ATOM 1728 C CD . GLU A 1 215 ? -38.997 29.622 0.907 1.00 53.13 ? 219 GLU A CD 1 ATOM 1729 O OE1 . GLU A 1 215 ? -39.618 29.866 -0.150 1.00 53.17 ? 219 GLU A OE1 1 ATOM 1730 O OE2 . GLU A 1 215 ? -38.305 28.588 1.056 1.00 53.57 ? 219 GLU A OE2 1 ATOM 1731 N N . THR A 1 216 ? -36.513 30.738 -0.702 1.00 51.98 ? 220 THR A N 1 ATOM 1732 C CA . THR A 1 216 ? -36.203 30.488 -2.120 1.00 52.46 ? 220 THR A CA 1 ATOM 1733 C C . THR A 1 216 ? -37.367 30.697 -3.113 1.00 53.33 ? 220 THR A C 1 ATOM 1734 O O . THR A 1 216 ? -37.143 31.016 -4.283 1.00 53.32 ? 220 THR A O 1 ATOM 1735 C CB . THR A 1 216 ? -35.562 29.100 -2.317 1.00 52.12 ? 220 THR A CB 1 ATOM 1736 O OG1 . THR A 1 216 ? -34.481 28.949 -1.392 1.00 51.66 ? 220 THR A OG1 1 ATOM 1737 C CG2 . THR A 1 216 ? -35.027 28.938 -3.730 1.00 51.62 ? 220 THR A CG2 1 ATOM 1738 N N . SER A 1 217 ? -38.600 30.524 -2.649 1.00 54.44 ? 221 SER A N 1 ATOM 1739 C CA . SER A 1 217 ? -39.760 30.631 -3.524 1.00 55.53 ? 221 SER A CA 1 ATOM 1740 C C . SER A 1 217 ? -40.451 31.994 -3.465 1.00 56.73 ? 221 SER A C 1 ATOM 1741 O O . SER A 1 217 ? -41.243 32.307 -4.354 1.00 56.94 ? 221 SER A O 1 ATOM 1742 C CB . SER A 1 217 ? -40.757 29.511 -3.229 1.00 55.40 ? 221 SER A CB 1 ATOM 1743 O OG . SER A 1 217 ? -40.194 28.240 -3.498 1.00 54.96 ? 221 SER A OG 1 ATOM 1744 N N . SER A 1 218 ? -40.144 32.794 -2.435 1.00 58.21 ? 222 SER A N 1 ATOM 1745 C CA . SER A 1 218 ? -40.746 34.131 -2.220 1.00 59.71 ? 222 SER A CA 1 ATOM 1746 C C . SER A 1 218 ? -40.939 34.963 -3.470 1.00 60.87 ? 222 SER A C 1 ATOM 1747 O O . SER A 1 218 ? -40.076 34.986 -4.356 1.00 61.02 ? 222 SER A O 1 ATOM 1748 C CB . SER A 1 218 ? -39.931 34.958 -1.231 1.00 59.51 ? 222 SER A CB 1 ATOM 1749 O OG . SER A 1 218 ? -40.618 35.105 -0.004 1.00 60.29 ? 222 SER A OG 1 ATOM 1750 N N . PHE A 1 219 ? -42.069 35.665 -3.520 1.00 62.40 ? 223 PHE A N 1 ATOM 1751 C CA . PHE A 1 219 ? -42.405 36.487 -4.679 1.00 63.87 ? 223 PHE A CA 1 ATOM 1752 C C . PHE A 1 219 ? -42.082 37.966 -4.489 1.00 64.75 ? 223 PHE A C 1 ATOM 1753 O O . PHE A 1 219 ? -42.137 38.504 -3.378 1.00 64.08 ? 223 PHE A O 1 ATOM 1754 C CB . PHE A 1 219 ? -43.864 36.285 -5.103 1.00 63.96 ? 223 PHE A CB 1 ATOM 1755 C CG . PHE A 1 219 ? -44.211 34.857 -5.425 1.00 64.71 ? 223 PHE A CG 1 ATOM 1756 C CD1 . PHE A 1 219 ? -43.637 34.213 -6.524 1.00 65.20 ? 223 PHE A CD1 1 ATOM 1757 C CD2 . PHE A 1 219 ? -45.122 34.151 -4.631 1.00 65.44 ? 223 PHE A CD2 1 ATOM 1758 C CE1 . PHE A 1 219 ? -43.958 32.879 -6.823 1.00 65.68 ? 223 PHE A CE1 1 ATOM 1759 C CE2 . PHE A 1 219 ? -45.458 32.822 -4.921 1.00 65.17 ? 223 PHE A CE2 1 ATOM 1760 C CZ . PHE A 1 219 ? -44.872 32.183 -6.018 1.00 65.26 ? 223 PHE A CZ 1 ATOM 1761 N N . GLY A 1 220 ? -41.730 38.598 -5.608 1.00 66.36 ? 224 GLY A N 1 ATOM 1762 C CA . GLY A 1 220 ? -41.333 40.005 -5.648 1.00 68.32 ? 224 GLY A CA 1 ATOM 1763 C C . GLY A 1 220 ? -42.517 40.946 -5.511 1.00 69.53 ? 224 GLY A C 1 ATOM 1764 O O . GLY A 1 220 ? -43.108 41.383 -6.519 1.00 69.67 ? 224 GLY A O 1 ATOM 1765 N N . GLU A 1 221 ? -42.862 41.244 -4.255 1.00 70.50 ? 225 GLU A N 1 ATOM 1766 C CA . GLU A 1 221 ? -43.905 42.218 -3.919 1.00 71.31 ? 225 GLU A CA 1 ATOM 1767 C C . GLU A 1 221 ? -43.665 43.565 -4.634 1.00 71.60 ? 225 GLU A C 1 ATOM 1768 O O . GLU A 1 221 ? -42.509 44.003 -4.765 1.00 71.99 ? 225 GLU A O 1 ATOM 1769 C CB . GLU A 1 221 ? -43.976 42.430 -2.394 1.00 71.31 ? 225 GLU A CB 1 ATOM 1770 C CG . GLU A 1 221 ? -44.703 41.325 -1.607 1.00 71.96 ? 225 GLU A CG 1 ATOM 1771 C CD . GLU A 1 221 ? -43.775 40.205 -1.136 1.00 72.61 ? 225 GLU A CD 1 ATOM 1772 O OE1 . GLU A 1 221 ? -44.017 39.033 -1.498 1.00 72.45 ? 225 GLU A OE1 1 ATOM 1773 O OE2 . GLU A 1 221 ? -42.806 40.489 -0.402 1.00 72.40 ? 225 GLU A OE2 1 ATOM 1774 N N . PRO A 1 222 ? -44.746 44.210 -5.129 1.00 71.58 ? 226 PRO A N 1 ATOM 1775 C CA . PRO A 1 222 ? -44.651 45.625 -5.534 1.00 71.31 ? 226 PRO A CA 1 ATOM 1776 C C . PRO A 1 222 ? -44.152 46.559 -4.402 1.00 70.90 ? 226 PRO A C 1 ATOM 1777 O O . PRO A 1 222 ? -43.817 47.722 -4.673 1.00 71.08 ? 226 PRO A O 1 ATOM 1778 C CB . PRO A 1 222 ? -46.094 45.974 -5.927 1.00 71.51 ? 226 PRO A CB 1 ATOM 1779 C CG . PRO A 1 222 ? -46.712 44.650 -6.322 1.00 71.82 ? 226 PRO A CG 1 ATOM 1780 C CD . PRO A 1 222 ? -46.091 43.649 -5.381 1.00 71.64 ? 226 PRO A CD 1 ATOM 1781 N N . ASN A 1 223 ? -44.100 46.044 -3.163 1.00 70.00 ? 227 ASN A N 1 ATOM 1782 C CA . ASN A 1 223 ? -43.627 46.791 -1.977 1.00 68.98 ? 227 ASN A CA 1 ATOM 1783 C C . ASN A 1 223 ? -42.397 46.189 -1.269 1.00 67.88 ? 227 ASN A C 1 ATOM 1784 O O . ASN A 1 223 ? -42.010 46.658 -0.199 1.00 67.86 ? 227 ASN A O 1 ATOM 1785 C CB . ASN A 1 223 ? -44.756 46.942 -0.948 1.00 69.20 ? 227 ASN A CB 1 ATOM 1786 C CG . ASN A 1 223 ? -44.935 45.690 -0.098 1.00 69.63 ? 227 ASN A CG 1 ATOM 1787 O OD1 . ASN A 1 223 ? -45.444 44.664 -0.566 1.00 70.00 ? 227 ASN A OD1 1 ATOM 1788 N ND2 . ASN A 1 223 ? -44.503 45.767 1.155 1.00 69.83 ? 227 ASN A ND2 1 ATOM 1789 N N . GLU A 1 224 ? -41.816 45.138 -1.845 1.00 66.57 ? 228 GLU A N 1 ATOM 1790 C CA . GLU A 1 224 ? -40.596 44.492 -1.324 1.00 65.19 ? 228 GLU A CA 1 ATOM 1791 C C . GLU A 1 224 ? -39.814 43.965 -2.532 1.00 63.61 ? 228 GLU A C 1 ATOM 1792 O O . GLU A 1 224 ? -40.257 43.021 -3.197 1.00 63.70 ? 228 GLU A O 1 ATOM 1793 C CB . GLU A 1 224 ? -40.939 43.349 -0.343 1.00 65.67 ? 228 GLU A CB 1 ATOM 1794 C CG . GLU A 1 224 ? -41.617 43.784 0.988 1.00 66.67 ? 228 GLU A CG 1 ATOM 1795 C CD . GLU A 1 224 ? -42.686 42.793 1.480 1.00 67.93 ? 228 GLU A CD 1 ATOM 1796 O OE1 . GLU A 1 224 ? -42.342 41.802 2.169 1.00 67.76 ? 228 GLU A OE1 1 ATOM 1797 O OE2 . GLU A 1 224 ? -43.880 43.012 1.178 1.00 68.69 ? 228 GLU A OE2 1 ATOM 1798 N N . ILE A 1 225 ? -38.670 44.588 -2.827 1.00 61.33 ? 229 ILE A N 1 ATOM 1799 C CA . ILE A 1 225 ? -37.990 44.401 -4.118 1.00 59.03 ? 229 ILE A CA 1 ATOM 1800 C C . ILE A 1 225 ? -36.917 43.318 -4.067 1.00 57.20 ? 229 ILE A C 1 ATOM 1801 O O . ILE A 1 225 ? -36.069 43.320 -3.178 1.00 57.04 ? 229 ILE A O 1 ATOM 1802 C CB . ILE A 1 225 ? -37.413 45.743 -4.659 1.00 59.37 ? 229 ILE A CB 1 ATOM 1803 C CG1 . ILE A 1 225 ? -38.535 46.792 -4.761 1.00 59.94 ? 229 ILE A CG1 1 ATOM 1804 C CG2 . ILE A 1 225 ? -36.697 45.548 -6.019 1.00 58.87 ? 229 ILE A CG2 1 ATOM 1805 C CD1 . ILE A 1 225 ? -38.070 48.257 -4.613 1.00 61.23 ? 229 ILE A CD1 1 ATOM 1806 N N . LEU A 1 226 ? -36.970 42.403 -5.032 1.00 54.98 ? 230 LEU A N 1 ATOM 1807 C CA . LEU A 1 226 ? -36.087 41.239 -5.066 1.00 53.05 ? 230 LEU A CA 1 ATOM 1808 C C . LEU A 1 226 ? -35.199 41.214 -6.293 1.00 51.91 ? 230 LEU A C 1 ATOM 1809 O O . LEU A 1 226 ? -35.584 41.694 -7.356 1.00 52.03 ? 230 LEU A O 1 ATOM 1810 C CB . LEU A 1 226 ? -36.896 39.935 -5.050 1.00 52.89 ? 230 LEU A CB 1 ATOM 1811 C CG . LEU A 1 226 ? -37.793 39.545 -3.872 1.00 52.11 ? 230 LEU A CG 1 ATOM 1812 C CD1 . LEU A 1 226 ? -38.262 38.123 -4.085 1.00 51.09 ? 230 LEU A CD1 1 ATOM 1813 C CD2 . LEU A 1 226 ? -37.093 39.686 -2.523 1.00 50.97 ? 230 LEU A CD2 1 ATOM 1814 N N . LYS A 1 227 ? -34.008 40.639 -6.136 1.00 50.40 ? 231 LYS A N 1 ATOM 1815 C CA . LYS A 1 227 ? -33.144 40.306 -7.268 1.00 48.55 ? 231 LYS A CA 1 ATOM 1816 C C . LYS A 1 227 ? -32.826 38.817 -7.221 1.00 47.20 ? 231 LYS A C 1 ATOM 1817 O O . LYS A 1 227 ? -32.891 38.199 -6.157 1.00 46.87 ? 231 LYS A O 1 ATOM 1818 C CB . LYS A 1 227 ? -31.856 41.142 -7.255 1.00 48.75 ? 231 LYS A CB 1 ATOM 1819 C CG . LYS A 1 227 ? -32.082 42.666 -7.232 1.00 48.78 ? 231 LYS A CG 1 ATOM 1820 C CD . LYS A 1 227 ? -31.405 43.366 -8.403 1.00 48.52 ? 231 LYS A CD 1 ATOM 1821 C CE . LYS A 1 227 ? -32.197 43.130 -9.674 1.00 48.75 ? 231 LYS A CE 1 ATOM 1822 N NZ . LYS A 1 227 ? -31.526 43.691 -10.860 1.00 49.72 ? 231 LYS A NZ 1 ATOM 1823 N N . HIS A 1 228 ? -32.497 38.239 -8.371 1.00 45.67 ? 232 HIS A N 1 ATOM 1824 C CA . HIS A 1 228 ? -32.116 36.833 -8.413 1.00 44.63 ? 232 HIS A CA 1 ATOM 1825 C C . HIS A 1 228 ? -30.651 36.576 -8.751 1.00 43.91 ? 232 HIS A C 1 ATOM 1826 O O . HIS A 1 228 ? -30.044 37.286 -9.552 1.00 43.88 ? 232 HIS A O 1 ATOM 1827 C CB . HIS A 1 228 ? -33.047 36.043 -9.325 1.00 44.71 ? 232 HIS A CB 1 ATOM 1828 C CG . HIS A 1 228 ? -34.342 35.685 -8.671 1.00 44.75 ? 232 HIS A CG 1 ATOM 1829 N ND1 . HIS A 1 228 ? -35.456 36.494 -8.734 1.00 45.30 ? 232 HIS A ND1 1 ATOM 1830 C CD2 . HIS A 1 228 ? -34.690 34.622 -7.910 1.00 45.17 ? 232 HIS A CD2 1 ATOM 1831 C CE1 . HIS A 1 228 ? -36.441 35.936 -8.053 1.00 45.36 ? 232 HIS A CE1 1 ATOM 1832 N NE2 . HIS A 1 228 ? -36.000 34.801 -7.539 1.00 45.56 ? 232 HIS A NE2 1 ATOM 1833 N N . VAL A 1 229 ? -30.091 35.553 -8.116 1.00 42.90 ? 233 VAL A N 1 ATOM 1834 C CA . VAL A 1 229 ? -28.690 35.203 -8.299 1.00 42.20 ? 233 VAL A CA 1 ATOM 1835 C C . VAL A 1 229 ? -28.590 33.833 -8.967 1.00 41.69 ? 233 VAL A C 1 ATOM 1836 O O . VAL A 1 229 ? -29.249 32.888 -8.542 1.00 41.91 ? 233 VAL A O 1 ATOM 1837 C CB . VAL A 1 229 ? -27.937 35.207 -6.932 1.00 42.33 ? 233 VAL A CB 1 ATOM 1838 C CG1 . VAL A 1 229 ? -26.496 34.744 -7.087 1.00 41.85 ? 233 VAL A CG1 1 ATOM 1839 C CG2 . VAL A 1 229 ? -27.990 36.607 -6.283 1.00 42.13 ? 233 VAL A CG2 1 ATOM 1840 N N . LEU A 1 230 ? -27.797 33.733 -10.028 1.00 40.94 ? 234 LEU A N 1 ATOM 1841 C CA . LEU A 1 230 ? -27.475 32.436 -10.617 1.00 40.46 ? 234 LEU A CA 1 ATOM 1842 C C . LEU A 1 230 ? -26.003 32.153 -10.421 1.00 40.33 ? 234 LEU A C 1 ATOM 1843 O O . LEU A 1 230 ? -25.156 32.935 -10.854 1.00 40.43 ? 234 LEU A O 1 ATOM 1844 C CB . LEU A 1 230 ? -27.814 32.393 -12.108 1.00 40.46 ? 234 LEU A CB 1 ATOM 1845 C CG . LEU A 1 230 ? -27.444 31.109 -12.865 1.00 39.48 ? 234 LEU A CG 1 ATOM 1846 C CD1 . LEU A 1 230 ? -28.480 30.007 -12.650 1.00 38.26 ? 234 LEU A CD1 1 ATOM 1847 C CD2 . LEU A 1 230 ? -27.283 31.408 -14.341 1.00 38.49 ? 234 LEU A CD2 1 ATOM 1848 N N . LYS A 1 231 ? -25.708 31.038 -9.763 1.00 40.28 ? 235 LYS A N 1 ATOM 1849 C CA . LYS A 1 231 ? -24.332 30.642 -9.476 1.00 40.31 ? 235 LYS A CA 1 ATOM 1850 C C . LYS A 1 231 ? -23.955 29.371 -10.236 1.00 40.46 ? 235 LYS A C 1 ATOM 1851 O O . LYS A 1 231 ? -24.727 28.411 -10.285 1.00 40.52 ? 235 LYS A O 1 ATOM 1852 C CB . LYS A 1 231 ? -24.132 30.457 -7.968 1.00 40.09 ? 235 LYS A CB 1 ATOM 1853 C CG . LYS A 1 231 ? -22.787 29.857 -7.571 1.00 39.25 ? 235 LYS A CG 1 ATOM 1854 C CD . LYS A 1 231 ? -22.847 28.331 -7.474 1.00 37.84 ? 235 LYS A CD 1 ATOM 1855 C CE . LYS A 1 231 ? -21.458 27.747 -7.246 1.00 36.90 ? 235 LYS A CE 1 ATOM 1856 N NZ . LYS A 1 231 ? -21.375 26.267 -7.357 1.00 35.45 ? 235 LYS A NZ 1 ATOM 1857 N N . ILE A 1 232 ? -22.763 29.372 -10.821 1.00 40.29 ? 236 ILE A N 1 ATOM 1858 C CA . ILE A 1 232 ? -22.289 28.233 -11.593 1.00 40.42 ? 236 ILE A CA 1 ATOM 1859 C C . ILE A 1 232 ? -20.862 27.873 -11.212 1.00 40.40 ? 236 ILE A C 1 ATOM 1860 O O . ILE A 1 232 ? -20.081 28.737 -10.808 1.00 40.62 ? 236 ILE A O 1 ATOM 1861 C CB . ILE A 1 232 ? -22.377 28.494 -13.124 1.00 40.52 ? 236 ILE A CB 1 ATOM 1862 C CG1 . ILE A 1 232 ? -21.570 29.748 -13.529 1.00 40.72 ? 236 ILE A CG1 1 ATOM 1863 C CG2 . ILE A 1 232 ? -23.853 28.581 -13.565 1.00 40.79 ? 236 ILE A CG2 1 ATOM 1864 C CD1 . ILE A 1 232 ? -21.567 30.078 -15.046 1.00 40.52 ? 236 ILE A CD1 1 ATOM 1865 N N . SER A 1 233 ? -20.528 26.594 -11.315 1.00 40.29 ? 237 SER A N 1 ATOM 1866 C CA . SER A 1 233 ? -19.150 26.176 -11.172 1.00 40.35 ? 237 SER A CA 1 ATOM 1867 C C . SER A 1 233 ? -18.648 25.800 -12.553 1.00 40.78 ? 237 SER A C 1 ATOM 1868 O O . SER A 1 233 ? -19.158 24.860 -13.171 1.00 40.82 ? 237 SER A O 1 ATOM 1869 C CB . SER A 1 233 ? -19.027 24.998 -10.208 1.00 40.11 ? 237 SER A CB 1 ATOM 1870 O OG . SER A 1 233 ? -19.109 25.424 -8.868 1.00 39.21 ? 237 SER A OG 1 ATOM 1871 N N . LEU A 1 234 ? -17.660 26.539 -13.050 1.00 41.14 ? 238 LEU A N 1 ATOM 1872 C CA . LEU A 1 234 ? -17.124 26.253 -14.374 1.00 41.52 ? 238 LEU A CA 1 ATOM 1873 C C . LEU A 1 234 ? -16.054 25.173 -14.338 1.00 41.81 ? 238 LEU A C 1 ATOM 1874 O O . LEU A 1 234 ? -14.933 25.408 -13.879 1.00 42.22 ? 238 LEU A O 1 ATOM 1875 C CB . LEU A 1 234 ? -16.632 27.526 -15.055 1.00 41.48 ? 238 LEU A CB 1 ATOM 1876 C CG . LEU A 1 234 ? -17.823 28.297 -15.624 1.00 42.23 ? 238 LEU A CG 1 ATOM 1877 C CD1 . LEU A 1 234 ? -17.399 29.640 -16.179 1.00 42.67 ? 238 LEU A CD1 1 ATOM 1878 C CD2 . LEU A 1 234 ? -18.535 27.468 -16.692 1.00 42.76 ? 238 LEU A CD2 1 ATOM 1879 N N . ASP A 1 235 ? -16.416 23.990 -14.834 1.00 41.86 ? 239 ASP A N 1 ATOM 1880 C CA . ASP A 1 235 ? -15.536 22.822 -14.834 1.00 41.86 ? 239 ASP A CA 1 ATOM 1881 C C . ASP A 1 235 ? -14.160 23.115 -15.433 1.00 41.66 ? 239 ASP A C 1 ATOM 1882 O O . ASP A 1 235 ? -13.159 22.574 -14.972 1.00 41.94 ? 239 ASP A O 1 ATOM 1883 C CB . ASP A 1 235 ? -16.205 21.644 -15.565 1.00 41.91 ? 239 ASP A CB 1 ATOM 1884 C CG . ASP A 1 235 ? -15.506 20.304 -15.308 1.00 42.52 ? 239 ASP A CG 1 ATOM 1885 O OD1 . ASP A 1 235 ? -15.767 19.346 -16.066 1.00 43.59 ? 239 ASP A OD1 1 ATOM 1886 O OD2 . ASP A 1 235 ? -14.707 20.188 -14.352 1.00 43.17 ? 239 ASP A OD2 1 ATOM 1887 N N . ASP A 1 236 ? -14.113 23.975 -16.445 1.00 41.39 ? 240 ASP A N 1 ATOM 1888 C CA . ASP A 1 236 ? -12.851 24.306 -17.112 1.00 41.31 ? 240 ASP A CA 1 ATOM 1889 C C . ASP A 1 236 ? -11.915 25.175 -16.247 1.00 41.09 ? 240 ASP A C 1 ATOM 1890 O O . ASP A 1 236 ? -10.758 24.818 -16.036 1.00 41.19 ? 240 ASP A O 1 ATOM 1891 C CB . ASP A 1 236 ? -13.110 24.996 -18.463 1.00 41.49 ? 240 ASP A CB 1 ATOM 1892 C CG . ASP A 1 236 ? -13.833 24.102 -19.473 1.00 41.18 ? 240 ASP A CG 1 ATOM 1893 O OD1 . ASP A 1 236 ? -14.348 24.663 -20.467 1.00 40.82 ? 240 ASP A OD1 1 ATOM 1894 O OD2 . ASP A 1 236 ? -13.887 22.863 -19.289 1.00 40.44 ? 240 ASP A OD2 1 ATOM 1895 N N . THR A 1 237 ? -12.422 26.301 -15.745 1.00 40.65 ? 241 THR A N 1 ATOM 1896 C CA . THR A 1 237 ? -11.612 27.259 -14.983 1.00 40.22 ? 241 THR A CA 1 ATOM 1897 C C . THR A 1 237 ? -11.441 26.853 -13.521 1.00 39.89 ? 241 THR A C 1 ATOM 1898 O O . THR A 1 237 ? -10.554 27.351 -12.821 1.00 39.91 ? 241 THR A O 1 ATOM 1899 C CB . THR A 1 237 ? -12.228 28.669 -15.013 1.00 40.36 ? 241 THR A CB 1 ATOM 1900 O OG1 . THR A 1 237 ? -13.419 28.691 -14.210 1.00 41.18 ? 241 THR A OG1 1 ATOM 1901 C CG2 . THR A 1 237 ? -12.555 29.102 -16.445 1.00 39.63 ? 241 THR A CG2 1 ATOM 1902 N N . LYS A 1 238 ? -12.301 25.943 -13.072 1.00 39.55 ? 242 LYS A N 1 ATOM 1903 C CA . LYS A 1 238 ? -12.375 25.512 -11.666 1.00 38.90 ? 242 LYS A CA 1 ATOM 1904 C C . LYS A 1 238 ? -12.691 26.644 -10.689 1.00 38.12 ? 242 LYS A C 1 ATOM 1905 O O . LYS A 1 238 ? -12.077 26.736 -9.631 1.00 38.20 ? 242 LYS A O 1 ATOM 1906 C CB . LYS A 1 238 ? -11.123 24.728 -11.236 1.00 39.01 ? 242 LYS A CB 1 ATOM 1907 C CG . LYS A 1 238 ? -11.296 23.193 -11.259 1.00 40.28 ? 242 LYS A CG 1 ATOM 1908 C CD . LYS A 1 238 ? -10.987 22.563 -12.646 1.00 41.96 ? 242 LYS A CD 1 ATOM 1909 C CE . LYS A 1 238 ? -11.296 21.059 -12.706 1.00 40.43 ? 242 LYS A CE 1 ATOM 1910 N NZ . LYS A 1 238 ? -12.739 20.786 -12.443 1.00 39.49 ? 242 LYS A NZ 1 ATOM 1911 N N . HIS A 1 239 ? -13.654 27.497 -11.051 1.00 37.13 ? 243 HIS A N 1 ATOM 1912 C CA . HIS A 1 239 ? -14.106 28.580 -10.180 1.00 36.15 ? 243 HIS A CA 1 ATOM 1913 C C . HIS A 1 239 ? -15.615 28.688 -10.117 1.00 36.05 ? 243 HIS A C 1 ATOM 1914 O O . HIS A 1 239 ? -16.324 28.246 -11.021 1.00 36.18 ? 243 HIS A O 1 ATOM 1915 C CB . HIS A 1 239 ? -13.558 29.931 -10.643 1.00 35.95 ? 243 HIS A CB 1 ATOM 1916 C CG . HIS A 1 239 ? -12.069 29.986 -10.732 1.00 34.96 ? 243 HIS A CG 1 ATOM 1917 N ND1 . HIS A 1 239 ? -11.413 30.532 -11.814 1.00 33.31 ? 243 HIS A ND1 1 ATOM 1918 C CD2 . HIS A 1 239 ? -11.105 29.558 -9.880 1.00 33.08 ? 243 HIS A CD2 1 ATOM 1919 C CE1 . HIS A 1 239 ? -10.111 30.442 -11.622 1.00 32.72 ? 243 HIS A CE1 1 ATOM 1920 N NE2 . HIS A 1 239 ? -9.898 29.852 -10.460 1.00 32.04 ? 243 HIS A NE2 1 ATOM 1921 N N . ASP A 1 240 ? -16.095 29.310 -9.049 1.00 35.96 ? 244 ASP A N 1 ATOM 1922 C CA . ASP A 1 240 ? -17.509 29.615 -8.899 1.00 35.99 ? 244 ASP A CA 1 ATOM 1923 C C . ASP A 1 240 ? -17.760 31.075 -9.223 1.00 35.90 ? 244 ASP A C 1 ATOM 1924 O O . ASP A 1 240 ? -17.060 31.955 -8.724 1.00 35.89 ? 244 ASP A O 1 ATOM 1925 C CB . ASP A 1 240 ? -17.981 29.307 -7.474 1.00 35.97 ? 244 ASP A CB 1 ATOM 1926 C CG . ASP A 1 240 ? -18.004 27.832 -7.180 1.00 35.62 ? 244 ASP A CG 1 ATOM 1927 O OD1 . ASP A 1 240 ? -17.538 27.049 -8.027 1.00 36.49 ? 244 ASP A OD1 1 ATOM 1928 O OD2 . ASP A 1 240 ? -18.489 27.446 -6.103 1.00 35.73 ? 244 ASP A OD2 1 ATOM 1929 N N . TYR A 1 241 ? -18.768 31.317 -10.053 1.00 35.77 ? 245 TYR A N 1 ATOM 1930 C CA . TYR A 1 241 ? -19.143 32.662 -10.475 1.00 35.56 ? 245 TYR A CA 1 ATOM 1931 C C . TYR A 1 241 ? -20.621 32.857 -10.181 1.00 36.08 ? 245 TYR A C 1 ATOM 1932 O O . TYR A 1 241 ? -21.399 31.902 -10.190 1.00 36.26 ? 245 TYR A O 1 ATOM 1933 C CB . TYR A 1 241 ? -18.904 32.841 -11.980 1.00 34.94 ? 245 TYR A CB 1 ATOM 1934 C CG . TYR A 1 241 ? -17.492 32.556 -12.462 1.00 34.26 ? 245 TYR A CG 1 ATOM 1935 C CD1 . TYR A 1 241 ? -17.078 31.253 -12.765 1.00 33.86 ? 245 TYR A CD1 1 ATOM 1936 C CD2 . TYR A 1 241 ? -16.571 33.593 -12.634 1.00 33.80 ? 245 TYR A CD2 1 ATOM 1937 C CE1 . TYR A 1 241 ? -15.775 30.998 -13.217 1.00 33.93 ? 245 TYR A CE1 1 ATOM 1938 C CE2 . TYR A 1 241 ? -15.261 33.347 -13.081 1.00 33.23 ? 245 TYR A CE2 1 ATOM 1939 C CZ . TYR A 1 241 ? -14.873 32.054 -13.370 1.00 33.97 ? 245 TYR A CZ 1 ATOM 1940 O OH . TYR A 1 241 ? -13.592 31.819 -13.813 1.00 34.12 ? 245 TYR A OH 1 ATOM 1941 N N . TYR A 1 242 ? -21.019 34.090 -9.916 1.00 36.75 ? 246 TYR A N 1 ATOM 1942 C CA . TYR A 1 242 ? -22.441 34.402 -9.816 1.00 37.74 ? 246 TYR A CA 1 ATOM 1943 C C . TYR A 1 242 ? -22.760 35.635 -10.655 1.00 38.44 ? 246 TYR A C 1 ATOM 1944 O O . TYR A 1 242 ? -21.847 36.380 -11.048 1.00 38.44 ? 246 TYR A O 1 ATOM 1945 C CB . TYR A 1 242 ? -22.872 34.605 -8.354 1.00 37.55 ? 246 TYR A CB 1 ATOM 1946 C CG . TYR A 1 242 ? -22.224 35.789 -7.689 1.00 37.63 ? 246 TYR A CG 1 ATOM 1947 C CD1 . TYR A 1 242 ? -22.774 37.064 -7.800 1.00 37.34 ? 246 TYR A CD1 1 ATOM 1948 C CD2 . TYR A 1 242 ? -21.044 35.639 -6.957 1.00 37.59 ? 246 TYR A CD2 1 ATOM 1949 C CE1 . TYR A 1 242 ? -22.167 38.163 -7.190 1.00 38.11 ? 246 TYR A CE1 1 ATOM 1950 C CE2 . TYR A 1 242 ? -20.432 36.729 -6.346 1.00 37.62 ? 246 TYR A CE2 1 ATOM 1951 C CZ . TYR A 1 242 ? -20.996 37.987 -6.466 1.00 37.49 ? 246 TYR A CZ 1 ATOM 1952 O OH . TYR A 1 242 ? -20.387 39.064 -5.864 1.00 37.11 ? 246 TYR A OH 1 ATOM 1953 N N . THR A 1 243 ? -24.047 35.836 -10.942 1.00 39.10 ? 247 THR A N 1 ATOM 1954 C CA . THR A 1 243 ? -24.494 37.053 -11.617 1.00 40.08 ? 247 THR A CA 1 ATOM 1955 C C . THR A 1 243 ? -25.840 37.492 -11.056 1.00 40.44 ? 247 THR A C 1 ATOM 1956 O O . THR A 1 243 ? -26.745 36.675 -10.896 1.00 40.71 ? 247 THR A O 1 ATOM 1957 C CB . THR A 1 243 ? -24.614 36.888 -13.161 1.00 40.25 ? 247 THR A CB 1 ATOM 1958 O OG1 . THR A 1 243 ? -25.665 35.970 -13.469 1.00 40.92 ? 247 THR A OG1 1 ATOM 1959 C CG2 . THR A 1 243 ? -23.314 36.389 -13.790 1.00 40.45 ? 247 THR A CG2 1 ATOM 1960 N N . ILE A 1 244 ? -25.962 38.784 -10.758 1.00 40.85 ? 248 ILE A N 1 ATOM 1961 C CA . ILE A 1 244 ? -27.200 39.365 -10.228 1.00 40.90 ? 248 ILE A CA 1 ATOM 1962 C C . ILE A 1 244 ? -28.124 39.804 -11.363 1.00 41.27 ? 248 ILE A C 1 ATOM 1963 O O . ILE A 1 244 ? -27.678 40.381 -12.349 1.00 41.05 ? 248 ILE A O 1 ATOM 1964 C CB . ILE A 1 244 ? -26.893 40.540 -9.293 1.00 40.64 ? 248 ILE A CB 1 ATOM 1965 C CG1 . ILE A 1 244 ? -25.816 40.126 -8.296 1.00 40.50 ? 248 ILE A CG1 1 ATOM 1966 C CG2 . ILE A 1 244 ? -28.136 40.961 -8.543 1.00 40.55 ? 248 ILE A CG2 1 ATOM 1967 C CD1 . ILE A 1 244 ? -24.953 41.248 -7.836 1.00 40.43 ? 248 ILE A CD1 1 ATOM 1968 N N . GLY A 1 245 ? -29.412 39.507 -11.223 1.00 42.20 ? 249 GLY A N 1 ATOM 1969 C CA . GLY A 1 245 ? -30.378 39.756 -12.287 1.00 43.46 ? 249 GLY A CA 1 ATOM 1970 C C . GLY A 1 245 ? -31.840 39.555 -11.931 1.00 44.35 ? 249 GLY A C 1 ATOM 1971 O O . GLY A 1 245 ? -32.191 39.249 -10.792 1.00 44.52 ? 249 GLY A O 1 ATOM 1972 N N . THR A 1 246 ? -32.697 39.752 -12.923 1.00 45.24 ? 250 THR A N 1 ATOM 1973 C CA . THR A 1 246 ? -34.126 39.601 -12.734 1.00 46.43 ? 250 THR A CA 1 ATOM 1974 C C . THR A 1 246 ? -34.559 38.242 -13.245 1.00 46.96 ? 250 THR A C 1 ATOM 1975 O O . THR A 1 246 ? -34.005 37.715 -14.210 1.00 46.81 ? 250 THR A O 1 ATOM 1976 C CB . THR A 1 246 ? -34.940 40.719 -13.443 1.00 46.40 ? 250 THR A CB 1 ATOM 1977 O OG1 . THR A 1 246 ? -34.187 41.233 -14.548 1.00 47.38 ? 250 THR A OG1 1 ATOM 1978 C CG2 . THR A 1 246 ? -35.237 41.861 -12.484 1.00 46.52 ? 250 THR A CG2 1 ATOM 1979 N N . TYR A 1 247 ? -35.549 37.676 -12.571 1.00 47.74 ? 251 TYR A N 1 ATOM 1980 C CA . TYR A 1 247 ? -36.114 36.412 -12.971 1.00 48.39 ? 251 TYR A CA 1 ATOM 1981 C C . TYR A 1 247 ? -37.474 36.732 -13.574 1.00 49.62 ? 251 TYR A C 1 ATOM 1982 O O . TYR A 1 247 ? -38.366 37.228 -12.890 1.00 49.90 ? 251 TYR A O 1 ATOM 1983 C CB . TYR A 1 247 ? -36.185 35.474 -11.756 1.00 47.49 ? 251 TYR A CB 1 ATOM 1984 C CG . TYR A 1 247 ? -36.904 34.157 -11.943 1.00 46.48 ? 251 TYR A CG 1 ATOM 1985 C CD1 . TYR A 1 247 ? -36.844 33.453 -13.144 1.00 45.41 ? 251 TYR A CD1 1 ATOM 1986 C CD2 . TYR A 1 247 ? -37.621 33.598 -10.894 1.00 45.76 ? 251 TYR A CD2 1 ATOM 1987 C CE1 . TYR A 1 247 ? -37.510 32.245 -13.299 1.00 44.73 ? 251 TYR A CE1 1 ATOM 1988 C CE2 . TYR A 1 247 ? -38.287 32.388 -11.041 1.00 45.38 ? 251 TYR A CE2 1 ATOM 1989 C CZ . TYR A 1 247 ? -38.229 31.719 -12.242 1.00 45.08 ? 251 TYR A CZ 1 ATOM 1990 O OH . TYR A 1 247 ? -38.889 30.520 -12.375 1.00 45.22 ? 251 TYR A OH 1 ATOM 1991 N N . ASP A 1 248 ? -37.586 36.504 -14.881 1.00 51.19 ? 252 ASP A N 1 ATOM 1992 C CA . ASP A 1 248 ? -38.833 36.648 -15.623 1.00 52.61 ? 252 ASP A CA 1 ATOM 1993 C C . ASP A 1 248 ? -39.626 35.354 -15.476 1.00 53.52 ? 252 ASP A C 1 ATOM 1994 O O . ASP A 1 248 ? -39.256 34.315 -16.045 1.00 53.62 ? 252 ASP A O 1 ATOM 1995 C CB . ASP A 1 248 ? -38.533 36.946 -17.104 1.00 52.85 ? 252 ASP A CB 1 ATOM 1996 C CG . ASP A 1 248 ? -39.793 37.010 -17.981 1.00 53.53 ? 252 ASP A CG 1 ATOM 1997 O OD1 . ASP A 1 248 ? -40.901 36.706 -17.484 1.00 54.23 ? 252 ASP A OD1 1 ATOM 1998 O OD2 . ASP A 1 248 ? -39.668 37.365 -19.180 1.00 53.21 ? 252 ASP A OD2 1 ATOM 1999 N N . ARG A 1 249 ? -40.714 35.435 -14.711 1.00 54.60 ? 253 ARG A N 1 ATOM 2000 C CA . ARG A 1 249 ? -41.595 34.292 -14.437 1.00 55.58 ? 253 ARG A CA 1 ATOM 2001 C C . ARG A 1 249 ? -42.358 33.833 -15.690 1.00 56.13 ? 253 ARG A C 1 ATOM 2002 O O . ARG A 1 249 ? -42.608 32.643 -15.867 1.00 56.40 ? 253 ARG A O 1 ATOM 2003 C CB . ARG A 1 249 ? -42.590 34.634 -13.320 1.00 55.55 ? 253 ARG A CB 1 ATOM 2004 C CG . ARG A 1 249 ? -41.987 35.396 -12.132 1.00 56.08 ? 253 ARG A CG 1 ATOM 2005 C CD . ARG A 1 249 ? -41.752 34.495 -10.927 1.00 56.51 ? 253 ARG A CD 1 ATOM 2006 N NE . ARG A 1 249 ? -41.015 35.176 -9.861 1.00 56.46 ? 253 ARG A NE 1 ATOM 2007 C CZ . ARG A 1 249 ? -40.590 34.598 -8.735 1.00 56.51 ? 253 ARG A CZ 1 ATOM 2008 N NH1 . ARG A 1 249 ? -40.830 33.310 -8.501 1.00 55.75 ? 253 ARG A NH1 1 ATOM 2009 N NH2 . ARG A 1 249 ? -39.920 35.314 -7.833 1.00 56.55 ? 253 ARG A NH2 1 ATOM 2010 N N . VAL A 1 250 ? -42.725 34.780 -16.550 1.00 56.92 ? 254 VAL A N 1 ATOM 2011 C CA . VAL A 1 250 ? -43.477 34.479 -17.772 1.00 57.45 ? 254 VAL A CA 1 ATOM 2012 C C . VAL A 1 250 ? -42.637 33.572 -18.670 1.00 57.92 ? 254 VAL A C 1 ATOM 2013 O O . VAL A 1 250 ? -42.957 32.384 -18.819 1.00 58.16 ? 254 VAL A O 1 ATOM 2014 C CB . VAL A 1 250 ? -43.935 35.776 -18.511 1.00 57.53 ? 254 VAL A CB 1 ATOM 2015 C CG1 . VAL A 1 250 ? -44.552 35.463 -19.883 1.00 57.14 ? 254 VAL A CG1 1 ATOM 2016 C CG2 . VAL A 1 250 ? -44.913 36.579 -17.633 1.00 57.54 ? 254 VAL A CG2 1 ATOM 2017 N N . LYS A 1 251 ? -41.557 34.119 -19.232 1.00 58.19 ? 255 LYS A N 1 ATOM 2018 C CA . LYS A 1 251 ? -40.633 33.338 -20.060 1.00 58.53 ? 255 LYS A CA 1 ATOM 2019 C C . LYS A 1 251 ? -40.031 32.146 -19.300 1.00 58.43 ? 255 LYS A C 1 ATOM 2020 O O . LYS A 1 251 ? -39.697 31.128 -19.912 1.00 58.46 ? 255 LYS A O 1 ATOM 2021 C CB . LYS A 1 251 ? -39.496 34.216 -20.603 1.00 58.85 ? 255 LYS A CB 1 ATOM 2022 C CG . LYS A 1 251 ? -39.831 35.058 -21.842 1.00 59.92 ? 255 LYS A CG 1 ATOM 2023 C CD . LYS A 1 251 ? -38.560 35.315 -22.688 1.00 61.35 ? 255 LYS A CD 1 ATOM 2024 C CE . LYS A 1 251 ? -38.757 36.381 -23.781 1.00 60.78 ? 255 LYS A CE 1 ATOM 2025 N NZ . LYS A 1 251 ? -38.744 37.783 -23.257 1.00 60.21 ? 255 LYS A NZ 1 ATOM 2026 N N . ASP A 1 252 ? -39.909 32.273 -17.974 1.00 58.22 ? 256 ASP A N 1 ATOM 2027 C CA . ASP A 1 252 ? -39.134 31.329 -17.159 1.00 57.85 ? 256 ASP A CA 1 ATOM 2028 C C . ASP A 1 252 ? -37.642 31.480 -17.513 1.00 57.42 ? 256 ASP A C 1 ATOM 2029 O O . ASP A 1 252 ? -36.931 30.493 -17.683 1.00 57.30 ? 256 ASP A O 1 ATOM 2030 C CB . ASP A 1 252 ? -39.624 29.886 -17.389 1.00 57.99 ? 256 ASP A CB 1 ATOM 2031 C CG . ASP A 1 252 ? -39.599 29.027 -16.125 1.00 58.33 ? 256 ASP A CG 1 ATOM 2032 O OD1 . ASP A 1 252 ? -39.471 27.793 -16.270 1.00 58.66 ? 256 ASP A OD1 1 ATOM 2033 O OD2 . ASP A 1 252 ? -39.729 29.565 -15.001 1.00 58.27 ? 256 ASP A OD2 1 ATOM 2034 N N . LYS A 1 253 ? -37.177 32.723 -17.641 1.00 56.94 ? 257 LYS A N 1 ATOM 2035 C CA . LYS A 1 253 ? -35.783 32.985 -18.025 1.00 56.71 ? 257 LYS A CA 1 ATOM 2036 C C . LYS A 1 253 ? -35.057 33.901 -17.053 1.00 55.93 ? 257 LYS A C 1 ATOM 2037 O O . LYS A 1 253 ? -35.637 34.850 -16.524 1.00 55.71 ? 257 LYS A O 1 ATOM 2038 C CB . LYS A 1 253 ? -35.683 33.565 -19.447 1.00 56.83 ? 257 LYS A CB 1 ATOM 2039 C CG . LYS A 1 253 ? -35.882 32.533 -20.563 1.00 57.73 ? 257 LYS A CG 1 ATOM 2040 C CD . LYS A 1 253 ? -35.442 33.053 -21.930 1.00 57.48 ? 257 LYS A CD 1 ATOM 2041 C CE . LYS A 1 253 ? -35.487 31.921 -22.971 1.00 59.12 ? 257 LYS A CE 1 ATOM 2042 N NZ . LYS A 1 253 ? -34.999 32.346 -24.323 1.00 58.84 ? 257 LYS A NZ 1 ATOM 2043 N N . PHE A 1 254 ? -33.782 33.607 -16.824 1.00 55.22 ? 258 PHE A N 1 ATOM 2044 C CA . PHE A 1 254 ? -32.949 34.495 -16.044 1.00 54.74 ? 258 PHE A CA 1 ATOM 2045 C C . PHE A 1 254 ? -32.240 35.487 -16.946 1.00 54.97 ? 258 PHE A C 1 ATOM 2046 O O . PHE A 1 254 ? -31.540 35.102 -17.888 1.00 54.99 ? 258 PHE A O 1 ATOM 2047 C CB . PHE A 1 254 ? -31.933 33.731 -15.198 1.00 54.23 ? 258 PHE A CB 1 ATOM 2048 C CG . PHE A 1 254 ? -31.029 34.628 -14.406 1.00 53.26 ? 258 PHE A CG 1 ATOM 2049 C CD1 . PHE A 1 254 ? -31.517 35.325 -13.300 1.00 52.12 ? 258 PHE A CD1 1 ATOM 2050 C CD2 . PHE A 1 254 ? -29.699 34.806 -14.784 1.00 51.98 ? 258 PHE A CD2 1 ATOM 2051 C CE1 . PHE A 1 254 ? -30.697 36.172 -12.577 1.00 51.29 ? 258 PHE A CE1 1 ATOM 2052 C CE2 . PHE A 1 254 ? -28.873 35.648 -14.071 1.00 51.24 ? 258 PHE A CE2 1 ATOM 2053 C CZ . PHE A 1 254 ? -29.373 36.333 -12.959 1.00 52.00 ? 258 PHE A CZ 1 ATOM 2054 N N . VAL A 1 255 ? -32.429 36.766 -16.641 1.00 55.29 ? 259 VAL A N 1 ATOM 2055 C CA . VAL A 1 255 ? -31.800 37.851 -17.375 1.00 55.97 ? 259 VAL A CA 1 ATOM 2056 C C . VAL A 1 255 ? -30.849 38.617 -16.448 1.00 56.48 ? 259 VAL A C 1 ATOM 2057 O O . VAL A 1 255 ? -31.298 39.323 -15.540 1.00 56.59 ? 259 VAL A O 1 ATOM 2058 C CB . VAL A 1 255 ? -32.856 38.820 -17.970 1.00 56.06 ? 259 VAL A CB 1 ATOM 2059 C CG1 . VAL A 1 255 ? -32.182 39.921 -18.805 1.00 56.08 ? 259 VAL A CG1 1 ATOM 2060 C CG2 . VAL A 1 255 ? -33.886 38.056 -18.807 1.00 55.91 ? 259 VAL A CG2 1 ATOM 2061 N N . PRO A 1 256 ? -29.530 38.482 -16.674 1.00 57.00 ? 260 PRO A N 1 ATOM 2062 C CA . PRO A 1 256 ? -28.554 39.190 -15.850 1.00 57.59 ? 260 PRO A CA 1 ATOM 2063 C C . PRO A 1 256 ? -28.604 40.661 -16.185 1.00 58.29 ? 260 PRO A C 1 ATOM 2064 O O . PRO A 1 256 ? -28.593 41.010 -17.367 1.00 58.40 ? 260 PRO A O 1 ATOM 2065 C CB . PRO A 1 256 ? -27.209 38.613 -16.311 1.00 57.48 ? 260 PRO A CB 1 ATOM 2066 C CG . PRO A 1 256 ? -27.547 37.408 -17.134 1.00 57.48 ? 260 PRO A CG 1 ATOM 2067 C CD . PRO A 1 256 ? -28.882 37.677 -17.719 1.00 56.95 ? 260 PRO A CD 1 ATOM 2068 N N . ASP A 1 257 ? -28.692 41.525 -15.178 1.00 59.24 ? 261 ASP A N 1 ATOM 2069 C CA . ASP A 1 257 ? -28.651 42.951 -15.476 1.00 60.14 ? 261 ASP A CA 1 ATOM 2070 C C . ASP A 1 257 ? -27.235 43.305 -15.878 1.00 61.02 ? 261 ASP A C 1 ATOM 2071 O O . ASP A 1 257 ? -26.356 43.422 -15.043 1.00 61.26 ? 261 ASP A O 1 ATOM 2072 C CB . ASP A 1 257 ? -29.212 43.853 -14.354 1.00 59.95 ? 261 ASP A CB 1 ATOM 2073 C CG . ASP A 1 257 ? -28.836 43.397 -12.960 1.00 58.51 ? 261 ASP A CG 1 ATOM 2074 O OD1 . ASP A 1 257 ? -27.675 43.561 -12.544 1.00 57.25 ? 261 ASP A OD1 1 ATOM 2075 O OD2 . ASP A 1 257 ? -29.735 42.922 -12.254 1.00 57.27 ? 261 ASP A OD2 1 ATOM 2076 N N . ASN A 1 258 ? -27.016 43.423 -17.180 1.00 62.22 ? 262 ASN A N 1 ATOM 2077 C CA . ASN A 1 258 ? -25.667 43.616 -17.693 1.00 63.41 ? 262 ASN A CA 1 ATOM 2078 C C . ASN A 1 258 ? -25.093 45.007 -17.345 1.00 63.72 ? 262 ASN A C 1 ATOM 2079 O O . ASN A 1 258 ? -25.844 45.964 -17.164 1.00 63.84 ? 262 ASN A O 1 ATOM 2080 C CB . ASN A 1 258 ? -25.553 43.215 -19.196 1.00 63.70 ? 262 ASN A CB 1 ATOM 2081 C CG . ASN A 1 258 ? -25.899 44.346 -20.171 1.00 64.50 ? 262 ASN A CG 1 ATOM 2082 O OD1 . ASN A 1 258 ? -26.925 45.022 -20.038 1.00 65.67 ? 262 ASN A OD1 1 ATOM 2083 N ND2 . ASN A 1 258 ? -25.051 44.522 -21.189 1.00 64.40 ? 262 ASN A ND2 1 ATOM 2084 N N . GLY A 1 259 ? -23.774 45.098 -17.196 1.00 64.08 ? 263 GLY A N 1 ATOM 2085 C CA . GLY A 1 259 ? -22.880 43.954 -17.360 1.00 64.43 ? 263 GLY A CA 1 ATOM 2086 C C . GLY A 1 259 ? -22.125 43.600 -16.095 1.00 64.60 ? 263 GLY A C 1 ATOM 2087 O O . GLY A 1 259 ? -21.640 44.495 -15.404 1.00 64.63 ? 263 GLY A O 1 ATOM 2088 N N . PHE A 1 260 ? -22.037 42.314 -15.744 1.00 64.77 ? 264 PHE A N 1 ATOM 2089 C CA . PHE A 1 260 ? -22.813 41.200 -16.316 1.00 64.70 ? 264 PHE A CA 1 ATOM 2090 C C . PHE A 1 260 ? -23.180 41.295 -17.797 1.00 64.69 ? 264 PHE A C 1 ATOM 2091 O O . PHE A 1 260 ? -22.484 40.752 -18.654 1.00 64.76 ? 264 PHE A O 1 ATOM 2092 C CB . PHE A 1 260 ? -24.065 40.956 -15.465 1.00 64.70 ? 264 PHE A CB 1 ATOM 2093 C CG . PHE A 1 260 ? -23.813 41.033 -13.978 1.00 64.42 ? 264 PHE A CG 1 ATOM 2094 C CD1 . PHE A 1 260 ? -22.845 40.235 -13.377 1.00 64.71 ? 264 PHE A CD1 1 ATOM 2095 C CD2 . PHE A 1 260 ? -24.541 41.908 -13.182 1.00 64.29 ? 264 PHE A CD2 1 ATOM 2096 C CE1 . PHE A 1 260 ? -22.611 40.316 -12.006 1.00 65.09 ? 264 PHE A CE1 1 ATOM 2097 C CE2 . PHE A 1 260 ? -24.312 41.997 -11.813 1.00 64.48 ? 264 PHE A CE2 1 ATOM 2098 C CZ . PHE A 1 260 ? -23.345 41.201 -11.224 1.00 64.69 ? 264 PHE A CZ 1 ATOM 2099 N N . GLY A 1 264 ? -18.074 39.414 -19.596 1.00 52.35 ? 268 GLY A N 1 ATOM 2100 C CA . GLY A 1 264 ? -17.947 38.729 -18.314 1.00 52.24 ? 268 GLY A CA 1 ATOM 2101 C C . GLY A 1 264 ? -16.526 38.219 -18.145 1.00 52.16 ? 268 GLY A C 1 ATOM 2102 O O . GLY A 1 264 ? -16.144 37.259 -18.831 1.00 52.27 ? 268 GLY A O 1 ATOM 2103 N N . THR A 1 265 ? -15.718 38.821 -17.259 1.00 51.83 ? 269 THR A N 1 ATOM 2104 C CA . THR A 1 265 ? -16.055 39.933 -16.329 1.00 51.37 ? 269 THR A CA 1 ATOM 2105 C C . THR A 1 265 ? -17.119 39.617 -15.241 1.00 50.52 ? 269 THR A C 1 ATOM 2106 O O . THR A 1 265 ? -17.830 40.522 -14.769 1.00 50.66 ? 269 THR A O 1 ATOM 2107 C CB . THR A 1 265 ? -16.341 41.325 -17.052 1.00 51.77 ? 269 THR A CB 1 ATOM 2108 O OG1 . THR A 1 265 ? -17.752 41.500 -17.290 1.00 52.29 ? 269 THR A OG1 1 ATOM 2109 C CG2 . THR A 1 265 ? -15.536 41.475 -18.375 1.00 51.96 ? 269 THR A CG2 1 ATOM 2110 N N . ALA A 1 266 ? -17.197 38.342 -14.837 1.00 48.94 ? 270 ALA A N 1 ATOM 2111 C CA . ALA A 1 266 ? -18.132 37.901 -13.781 1.00 47.05 ? 270 ALA A CA 1 ATOM 2112 C C . ALA A 1 266 ? -17.476 37.746 -12.392 1.00 45.34 ? 270 ALA A C 1 ATOM 2113 O O . ALA A 1 266 ? -16.381 37.186 -12.283 1.00 45.30 ? 270 ALA A O 1 ATOM 2114 C CB . ALA A 1 266 ? -18.842 36.601 -14.193 1.00 47.06 ? 270 ALA A CB 1 ATOM 2115 N N . PRO A 1 267 ? -18.149 38.245 -11.331 1.00 43.41 ? 271 PRO A N 1 ATOM 2116 C CA . PRO A 1 267 ? -17.721 38.117 -9.937 1.00 41.89 ? 271 PRO A CA 1 ATOM 2117 C C . PRO A 1 267 ? -17.643 36.676 -9.446 1.00 40.49 ? 271 PRO A C 1 ATOM 2118 O O . PRO A 1 267 ? -18.427 35.835 -9.879 1.00 40.63 ? 271 PRO A O 1 ATOM 2119 C CB . PRO A 1 267 ? -18.834 38.837 -9.166 1.00 41.66 ? 271 PRO A CB 1 ATOM 2120 C CG . PRO A 1 267 ? -19.448 39.736 -10.124 1.00 42.09 ? 271 PRO A CG 1 ATOM 2121 C CD . PRO A 1 267 ? -19.398 39.016 -11.427 1.00 43.35 ? 271 PRO A CD 1 ATOM 2122 N N . ARG A 1 268 ? -16.706 36.401 -8.545 1.00 38.75 ? 272 ARG A N 1 ATOM 2123 C CA . ARG A 1 268 ? -16.672 35.129 -7.839 1.00 37.30 ? 272 ARG A CA 1 ATOM 2124 C C . ARG A 1 268 ? -17.092 35.382 -6.405 1.00 36.64 ? 272 ARG A C 1 ATOM 2125 O O . ARG A 1 268 ? -16.915 36.491 -5.898 1.00 37.09 ? 272 ARG A O 1 ATOM 2126 C CB . ARG A 1 268 ? -15.267 34.549 -7.821 1.00 37.05 ? 272 ARG A CB 1 ATOM 2127 C CG . ARG A 1 268 ? -14.654 34.262 -9.157 1.00 36.64 ? 272 ARG A CG 1 ATOM 2128 C CD . ARG A 1 268 ? -13.229 33.822 -8.927 1.00 36.41 ? 272 ARG A CD 1 ATOM 2129 N NE . ARG A 1 268 ? -12.345 34.078 -10.062 1.00 35.58 ? 272 ARG A NE 1 ATOM 2130 C CZ . ARG A 1 268 ? -11.101 33.619 -10.144 1.00 34.79 ? 272 ARG A CZ 1 ATOM 2131 N NH1 . ARG A 1 268 ? -10.595 32.876 -9.170 1.00 36.04 ? 272 ARG A NH1 1 ATOM 2132 N NH2 . ARG A 1 268 ? -10.364 33.883 -11.203 1.00 34.97 ? 272 ARG A NH2 1 ATOM 2133 N N . TYR A 1 269 ? -17.639 34.368 -5.737 1.00 35.42 ? 273 TYR A N 1 ATOM 2134 C CA . TYR A 1 269 ? -17.805 34.454 -4.295 1.00 34.11 ? 273 TYR A CA 1 ATOM 2135 C C . TYR A 1 269 ? -16.425 34.645 -3.693 1.00 33.42 ? 273 TYR A C 1 ATOM 2136 O O . TYR A 1 269 ? -16.236 35.477 -2.827 1.00 33.38 ? 273 TYR A O 1 ATOM 2137 C CB . TYR A 1 269 ? -18.381 33.168 -3.704 1.00 33.86 ? 273 TYR A CB 1 ATOM 2138 C CG . TYR A 1 269 ? -19.807 32.850 -4.036 1.00 32.91 ? 273 TYR A CG 1 ATOM 2139 C CD1 . TYR A 1 269 ? -20.802 33.809 -3.941 1.00 33.02 ? 273 TYR A CD1 1 ATOM 2140 C CD2 . TYR A 1 269 ? -20.171 31.557 -4.391 1.00 33.35 ? 273 TYR A CD2 1 ATOM 2141 C CE1 . TYR A 1 269 ? -22.133 33.497 -4.223 1.00 33.22 ? 273 TYR A CE1 1 ATOM 2142 C CE2 . TYR A 1 269 ? -21.494 31.230 -4.679 1.00 33.59 ? 273 TYR A CE2 1 ATOM 2143 C CZ . TYR A 1 269 ? -22.470 32.204 -4.594 1.00 33.37 ? 273 TYR A CZ 1 ATOM 2144 O OH . TYR A 1 269 ? -23.775 31.882 -4.882 1.00 32.84 ? 273 TYR A OH 1 ATOM 2145 N N . ASP A 1 270 ? -15.466 33.858 -4.175 1.00 32.87 ? 274 ASP A N 1 ATOM 2146 C CA . ASP A 1 270 ? -14.141 33.741 -3.552 1.00 32.57 ? 274 ASP A CA 1 ATOM 2147 C C . ASP A 1 270 ? -13.027 33.746 -4.621 1.00 32.29 ? 274 ASP A C 1 ATOM 2148 O O . ASP A 1 270 ? -13.091 33.014 -5.610 1.00 32.03 ? 274 ASP A O 1 ATOM 2149 C CB . ASP A 1 270 ? -14.111 32.465 -2.687 1.00 32.22 ? 274 ASP A CB 1 ATOM 2150 C CG . ASP A 1 270 ? -12.858 32.331 -1.838 1.00 31.14 ? 274 ASP A CG 1 ATOM 2151 O OD1 . ASP A 1 270 ? -13.014 32.112 -0.621 1.00 28.73 ? 274 ASP A OD1 1 ATOM 2152 O OD2 . ASP A 1 270 ? -11.728 32.406 -2.378 1.00 30.83 ? 274 ASP A OD2 1 ATOM 2153 N N . TYR A 1 271 ? -12.013 34.579 -4.423 1.00 32.12 ? 275 TYR A N 1 ATOM 2154 C CA . TYR A 1 271 ? -10.989 34.752 -5.457 1.00 32.35 ? 275 TYR A CA 1 ATOM 2155 C C . TYR A 1 271 ? -9.736 33.886 -5.282 1.00 32.58 ? 275 TYR A C 1 ATOM 2156 O O . TYR A 1 271 ? -8.706 34.145 -5.903 1.00 32.76 ? 275 TYR A O 1 ATOM 2157 C CB . TYR A 1 271 ? -10.662 36.235 -5.650 1.00 31.95 ? 275 TYR A CB 1 ATOM 2158 C CG . TYR A 1 271 ? -11.799 36.954 -6.337 1.00 31.67 ? 275 TYR A CG 1 ATOM 2159 C CD1 . TYR A 1 271 ? -11.827 37.077 -7.727 1.00 30.93 ? 275 TYR A CD1 1 ATOM 2160 C CD2 . TYR A 1 271 ? -12.872 37.471 -5.603 1.00 31.78 ? 275 TYR A CD2 1 ATOM 2161 C CE1 . TYR A 1 271 ? -12.880 37.716 -8.378 1.00 31.23 ? 275 TYR A CE1 1 ATOM 2162 C CE2 . TYR A 1 271 ? -13.937 38.118 -6.246 1.00 32.60 ? 275 TYR A CE2 1 ATOM 2163 C CZ . TYR A 1 271 ? -13.935 38.235 -7.635 1.00 32.15 ? 275 TYR A CZ 1 ATOM 2164 O OH . TYR A 1 271 ? -14.978 38.866 -8.280 1.00 31.54 ? 275 TYR A OH 1 ATOM 2165 N N . GLY A 1 272 ? -9.853 32.853 -4.447 1.00 32.80 ? 276 GLY A N 1 ATOM 2166 C CA . GLY A 1 272 ? -8.782 31.892 -4.202 1.00 32.54 ? 276 GLY A CA 1 ATOM 2167 C C . GLY A 1 272 ? -9.291 30.482 -4.424 1.00 32.80 ? 276 GLY A C 1 ATOM 2168 O O . GLY A 1 272 ? -10.111 30.253 -5.320 1.00 33.14 ? 276 GLY A O 1 ATOM 2169 N N . LYS A 1 273 ? -8.825 29.536 -3.609 1.00 32.36 ? 277 LYS A N 1 ATOM 2170 C CA . LYS A 1 273 ? -9.197 28.133 -3.772 1.00 31.99 ? 277 LYS A CA 1 ATOM 2171 C C . LYS A 1 273 ? -10.565 27.846 -3.176 1.00 31.76 ? 277 LYS A C 1 ATOM 2172 O O . LYS A 1 273 ? -10.697 27.672 -1.972 1.00 31.98 ? 277 LYS A O 1 ATOM 2173 C CB . LYS A 1 273 ? -8.150 27.228 -3.130 1.00 32.08 ? 277 LYS A CB 1 ATOM 2174 C CG . LYS A 1 273 ? -8.278 25.774 -3.525 1.00 32.58 ? 277 LYS A CG 1 ATOM 2175 C CD . LYS A 1 273 ? -7.881 25.556 -4.985 1.00 32.63 ? 277 LYS A CD 1 ATOM 2176 C CE . LYS A 1 273 ? -6.374 25.385 -5.122 1.00 34.27 ? 277 LYS A CE 1 ATOM 2177 N NZ . LYS A 1 273 ? -5.839 24.240 -4.307 1.00 34.91 ? 277 LYS A NZ 1 ATOM 2178 N N . TYR A 1 274 ? -11.578 27.772 -4.031 1.00 31.64 ? 278 TYR A N 1 ATOM 2179 C CA . TYR A 1 274 ? -12.972 27.695 -3.598 1.00 31.39 ? 278 TYR A CA 1 ATOM 2180 C C . TYR A 1 274 ? -13.800 27.146 -4.751 1.00 31.49 ? 278 TYR A C 1 ATOM 2181 O O . TYR A 1 274 ? -13.757 27.682 -5.853 1.00 31.60 ? 278 TYR A O 1 ATOM 2182 C CB . TYR A 1 274 ? -13.455 29.102 -3.222 1.00 31.22 ? 278 TYR A CB 1 ATOM 2183 C CG . TYR A 1 274 ? -14.798 29.165 -2.545 1.00 30.74 ? 278 TYR A CG 1 ATOM 2184 C CD1 . TYR A 1 274 ? -14.901 29.118 -1.156 1.00 30.19 ? 278 TYR A CD1 1 ATOM 2185 C CD2 . TYR A 1 274 ? -15.969 29.284 -3.290 1.00 30.37 ? 278 TYR A CD2 1 ATOM 2186 C CE1 . TYR A 1 274 ? -16.141 29.170 -0.522 1.00 29.55 ? 278 TYR A CE1 1 ATOM 2187 C CE2 . TYR A 1 274 ? -17.214 29.334 -2.670 1.00 29.96 ? 278 TYR A CE2 1 ATOM 2188 C CZ . TYR A 1 274 ? -17.293 29.276 -1.288 1.00 30.47 ? 278 TYR A CZ 1 ATOM 2189 O OH . TYR A 1 274 ? -18.526 29.333 -0.670 1.00 30.88 ? 278 TYR A OH 1 ATOM 2190 N N . TYR A 1 275 ? -14.562 26.088 -4.504 1.00 32.00 ? 279 TYR A N 1 ATOM 2191 C CA . TYR A 1 275 ? -15.317 25.431 -5.581 1.00 32.41 ? 279 TYR A CA 1 ATOM 2192 C C . TYR A 1 275 ? -16.525 24.628 -5.107 1.00 32.53 ? 279 TYR A C 1 ATOM 2193 O O . TYR A 1 275 ? -16.635 24.290 -3.927 1.00 32.61 ? 279 TYR A O 1 ATOM 2194 C CB . TYR A 1 275 ? -14.396 24.522 -6.391 1.00 32.29 ? 279 TYR A CB 1 ATOM 2195 C CG . TYR A 1 275 ? -14.963 24.118 -7.730 1.00 32.61 ? 279 TYR A CG 1 ATOM 2196 C CD1 . TYR A 1 275 ? -15.015 25.024 -8.788 1.00 33.01 ? 279 TYR A CD1 1 ATOM 2197 C CD2 . TYR A 1 275 ? -15.443 22.827 -7.947 1.00 31.92 ? 279 TYR A CD2 1 ATOM 2198 C CE1 . TYR A 1 275 ? -15.533 24.645 -10.034 1.00 32.19 ? 279 TYR A CE1 1 ATOM 2199 C CE2 . TYR A 1 275 ? -15.962 22.449 -9.178 1.00 30.97 ? 279 TYR A CE2 1 ATOM 2200 C CZ . TYR A 1 275 ? -16.002 23.361 -10.210 1.00 31.58 ? 279 TYR A CZ 1 ATOM 2201 O OH . TYR A 1 275 ? -16.513 22.988 -11.426 1.00 32.55 ? 279 TYR A OH 1 ATOM 2202 N N . ALA A 1 276 ? -17.416 24.332 -6.056 1.00 32.72 ? 280 ALA A N 1 ATOM 2203 C CA . ALA A 1 276 ? -18.630 23.527 -5.852 1.00 33.02 ? 280 ALA A CA 1 ATOM 2204 C C . ALA A 1 276 ? -19.532 24.038 -4.716 1.00 33.39 ? 280 ALA A C 1 ATOM 2205 O O . ALA A 1 276 ? -20.129 23.255 -3.980 1.00 33.59 ? 280 ALA A O 1 ATOM 2206 C CB . ALA A 1 276 ? -18.272 22.062 -5.661 1.00 32.55 ? 280 ALA A CB 1 ATOM 2207 N N . SER A 1 277 ? -19.643 25.358 -4.593 1.00 33.62 ? 281 SER A N 1 ATOM 2208 C CA . SER A 1 277 ? -20.363 25.946 -3.479 1.00 33.90 ? 281 SER A CA 1 ATOM 2209 C C . SER A 1 277 ? -21.874 25.883 -3.653 1.00 34.08 ? 281 SER A C 1 ATOM 2210 O O . SER A 1 277 ? -22.382 25.790 -4.769 1.00 34.42 ? 281 SER A O 1 ATOM 2211 C CB . SER A 1 277 ? -19.903 27.379 -3.247 1.00 33.99 ? 281 SER A CB 1 ATOM 2212 O OG . SER A 1 277 ? -20.441 28.249 -4.217 1.00 34.91 ? 281 SER A OG 1 ATOM 2213 N N . LYS A 1 278 ? -22.589 25.922 -2.533 1.00 34.34 ? 282 LYS A N 1 ATOM 2214 C CA . LYS A 1 278 ? -24.040 25.745 -2.521 1.00 34.27 ? 282 LYS A CA 1 ATOM 2215 C C . LYS A 1 278 ? -24.617 26.463 -1.320 1.00 34.74 ? 282 LYS A C 1 ATOM 2216 O O . LYS A 1 278 ? -24.007 26.483 -0.236 1.00 34.87 ? 282 LYS A O 1 ATOM 2217 C CB . LYS A 1 278 ? -24.415 24.256 -2.457 1.00 34.49 ? 282 LYS A CB 1 ATOM 2218 C CG . LYS A 1 278 ? -25.905 23.968 -2.637 1.00 34.01 ? 282 LYS A CG 1 ATOM 2219 C CD . LYS A 1 278 ? -26.209 22.477 -2.681 1.00 33.65 ? 282 LYS A CD 1 ATOM 2220 C CE . LYS A 1 278 ? -25.928 21.861 -4.044 1.00 31.29 ? 282 LYS A CE 1 ATOM 2221 N NZ . LYS A 1 278 ? -26.666 22.552 -5.110 1.00 29.58 ? 282 LYS A NZ 1 ATOM 2222 N N . THR A 1 279 ? -25.796 27.045 -1.519 1.00 34.95 ? 283 THR A N 1 ATOM 2223 C CA . THR A 1 279 ? -26.481 27.783 -0.471 1.00 35.09 ? 283 THR A CA 1 ATOM 2224 C C . THR A 1 279 ? -27.674 26.991 0.035 1.00 35.10 ? 283 THR A C 1 ATOM 2225 O O . THR A 1 279 ? -28.115 26.049 -0.609 1.00 35.06 ? 283 THR A O 1 ATOM 2226 C CB . THR A 1 279 ? -26.994 29.131 -0.999 1.00 35.15 ? 283 THR A CB 1 ATOM 2227 O OG1 . THR A 1 279 ? -27.795 28.891 -2.154 1.00 34.85 ? 283 THR A OG1 1 ATOM 2228 C CG2 . THR A 1 279 ? -25.837 30.055 -1.373 1.00 34.49 ? 283 THR A CG2 1 ATOM 2229 N N . PHE A 1 280 ? -28.178 27.370 1.203 1.00 35.44 ? 284 PHE A N 1 ATOM 2230 C CA . PHE A 1 280 ? -29.504 26.944 1.650 1.00 35.74 ? 284 PHE A CA 1 ATOM 2231 C C . PHE A 1 280 ? -30.146 28.064 2.462 1.00 36.11 ? 284 PHE A C 1 ATOM 2232 O O . PHE A 1 280 ? -29.469 29.004 2.900 1.00 35.98 ? 284 PHE A O 1 ATOM 2233 C CB . PHE A 1 280 ? -29.435 25.642 2.456 1.00 35.49 ? 284 PHE A CB 1 ATOM 2234 C CG . PHE A 1 280 ? -28.911 25.818 3.853 1.00 35.20 ? 284 PHE A CG 1 ATOM 2235 C CD1 . PHE A 1 280 ? -29.786 25.916 4.928 1.00 33.84 ? 284 PHE A CD1 1 ATOM 2236 C CD2 . PHE A 1 280 ? -27.542 25.887 4.094 1.00 35.17 ? 284 PHE A CD2 1 ATOM 2237 C CE1 . PHE A 1 280 ? -29.306 26.078 6.222 1.00 33.69 ? 284 PHE A CE1 1 ATOM 2238 C CE2 . PHE A 1 280 ? -27.053 26.048 5.392 1.00 35.12 ? 284 PHE A CE2 1 ATOM 2239 C CZ . PHE A 1 280 ? -27.938 26.150 6.455 1.00 34.15 ? 284 PHE A CZ 1 ATOM 2240 N N . PHE A 1 281 ? -31.455 27.979 2.645 1.00 36.70 ? 285 PHE A N 1 ATOM 2241 C CA . PHE A 1 281 ? -32.144 28.983 3.441 1.00 37.49 ? 285 PHE A CA 1 ATOM 2242 C C . PHE A 1 281 ? -32.206 28.569 4.909 1.00 38.08 ? 285 PHE A C 1 ATOM 2243 O O . PHE A 1 281 ? -32.755 27.513 5.258 1.00 38.17 ? 285 PHE A O 1 ATOM 2244 C CB . PHE A 1 281 ? -33.541 29.281 2.897 1.00 37.03 ? 285 PHE A CB 1 ATOM 2245 C CG . PHE A 1 281 ? -34.261 30.354 3.656 1.00 37.73 ? 285 PHE A CG 1 ATOM 2246 C CD1 . PHE A 1 281 ? -33.668 31.607 3.856 1.00 37.64 ? 285 PHE A CD1 1 ATOM 2247 C CD2 . PHE A 1 281 ? -35.537 30.121 4.184 1.00 37.81 ? 285 PHE A CD2 1 ATOM 2248 C CE1 . PHE A 1 281 ? -34.340 32.606 4.566 1.00 37.15 ? 285 PHE A CE1 1 ATOM 2249 C CE2 . PHE A 1 281 ? -36.213 31.114 4.896 1.00 36.35 ? 285 PHE A CE2 1 ATOM 2250 C CZ . PHE A 1 281 ? -35.616 32.353 5.087 1.00 36.61 ? 285 PHE A CZ 1 ATOM 2251 N N . ASP A 1 282 ? -31.625 29.399 5.765 1.00 38.53 ? 286 ASP A N 1 ATOM 2252 C CA . ASP A 1 282 ? -31.697 29.163 7.192 1.00 39.20 ? 286 ASP A CA 1 ATOM 2253 C C . ASP A 1 282 ? -32.960 29.840 7.718 1.00 39.44 ? 286 ASP A C 1 ATOM 2254 O O . ASP A 1 282 ? -32.948 31.032 8.050 1.00 39.75 ? 286 ASP A O 1 ATOM 2255 C CB . ASP A 1 282 ? -30.442 29.709 7.867 1.00 39.41 ? 286 ASP A CB 1 ATOM 2256 C CG . ASP A 1 282 ? -30.442 29.502 9.354 1.00 40.55 ? 286 ASP A CG 1 ATOM 2257 O OD1 . ASP A 1 282 ? -31.463 29.045 9.898 1.00 42.29 ? 286 ASP A OD1 1 ATOM 2258 O OD2 . ASP A 1 282 ? -29.413 29.804 9.990 1.00 42.80 ? 286 ASP A OD2 1 ATOM 2259 N N . SER A 1 283 ? -34.049 29.074 7.777 1.00 39.68 ? 287 SER A N 1 ATOM 2260 C CA . SER A 1 283 ? -35.362 29.593 8.173 1.00 39.71 ? 287 SER A CA 1 ATOM 2261 C C . SER A 1 283 ? -35.422 29.963 9.659 1.00 40.48 ? 287 SER A C 1 ATOM 2262 O O . SER A 1 283 ? -36.211 30.836 10.055 1.00 40.86 ? 287 SER A O 1 ATOM 2263 C CB . SER A 1 283 ? -36.477 28.615 7.807 1.00 39.23 ? 287 SER A CB 1 ATOM 2264 O OG . SER A 1 283 ? -36.191 27.314 8.276 1.00 37.94 ? 287 SER A OG 1 ATOM 2265 N N . ALA A 1 284 ? -34.576 29.321 10.467 1.00 40.79 ? 288 ALA A N 1 ATOM 2266 C CA . ALA A 1 284 ? -34.461 29.643 11.889 1.00 41.23 ? 288 ALA A CA 1 ATOM 2267 C C . ALA A 1 284 ? -34.061 31.094 12.132 1.00 41.69 ? 288 ALA A C 1 ATOM 2268 O O . ALA A 1 284 ? -34.657 31.754 12.975 1.00 42.11 ? 288 ALA A O 1 ATOM 2269 C CB . ALA A 1 284 ? -33.492 28.708 12.578 1.00 41.17 ? 288 ALA A CB 1 ATOM 2270 N N . LYS A 1 285 ? -33.075 31.594 11.386 1.00 42.21 ? 289 LYS A N 1 ATOM 2271 C CA . LYS A 1 285 ? -32.560 32.960 11.589 1.00 42.51 ? 289 LYS A CA 1 ATOM 2272 C C . LYS A 1 285 ? -32.653 33.900 10.374 1.00 42.43 ? 289 LYS A C 1 ATOM 2273 O O . LYS A 1 285 ? -32.045 34.966 10.381 1.00 42.24 ? 289 LYS A O 1 ATOM 2274 C CB . LYS A 1 285 ? -31.111 32.914 12.087 1.00 42.79 ? 289 LYS A CB 1 ATOM 2275 C CG . LYS A 1 285 ? -30.939 32.288 13.463 1.00 44.07 ? 289 LYS A CG 1 ATOM 2276 C CD . LYS A 1 285 ? -29.497 32.381 13.921 1.00 45.36 ? 289 LYS A CD 1 ATOM 2277 C CE . LYS A 1 285 ? -29.320 31.829 15.324 1.00 46.70 ? 289 LYS A CE 1 ATOM 2278 N NZ . LYS A 1 285 ? -28.061 32.365 15.925 1.00 47.42 ? 289 LYS A NZ 1 ATOM 2279 N N . ASN A 1 286 ? -33.409 33.514 9.344 1.00 42.60 ? 290 ASN A N 1 ATOM 2280 C CA . ASN A 1 286 ? -33.597 34.346 8.140 1.00 42.44 ? 290 ASN A CA 1 ATOM 2281 C C . ASN A 1 286 ? -32.297 34.865 7.532 1.00 41.90 ? 290 ASN A C 1 ATOM 2282 O O . ASN A 1 286 ? -32.127 36.074 7.337 1.00 42.30 ? 290 ASN A O 1 ATOM 2283 C CB . ASN A 1 286 ? -34.514 35.532 8.432 1.00 42.76 ? 290 ASN A CB 1 ATOM 2284 C CG . ASN A 1 286 ? -35.911 35.108 8.780 1.00 44.56 ? 290 ASN A CG 1 ATOM 2285 O OD1 . ASN A 1 286 ? -36.627 34.540 7.946 1.00 47.06 ? 290 ASN A OD1 1 ATOM 2286 N ND2 . ASN A 1 286 ? -36.323 35.389 10.017 1.00 45.63 ? 290 ASN A ND2 1 ATOM 2287 N N . ARG A 1 287 ? -31.376 33.952 7.258 1.00 40.78 ? 291 ARG A N 1 ATOM 2288 C CA . ARG A 1 287 ? -30.147 34.279 6.550 1.00 39.53 ? 291 ARG A CA 1 ATOM 2289 C C . ARG A 1 287 ? -29.960 33.200 5.495 1.00 39.48 ? 291 ARG A C 1 ATOM 2290 O O . ARG A 1 287 ? -30.430 32.062 5.678 1.00 39.75 ? 291 ARG A O 1 ATOM 2291 C CB . ARG A 1 287 ? -28.956 34.306 7.509 1.00 39.31 ? 291 ARG A CB 1 ATOM 2292 C CG . ARG A 1 287 ? -28.965 33.151 8.500 1.00 39.00 ? 291 ARG A CG 1 ATOM 2293 C CD . ARG A 1 287 ? -27.847 33.207 9.520 1.00 38.14 ? 291 ARG A CD 1 ATOM 2294 N NE . ARG A 1 287 ? -27.810 31.947 10.244 1.00 35.58 ? 291 ARG A NE 1 ATOM 2295 C CZ . ARG A 1 287 ? -26.848 31.574 11.081 1.00 36.25 ? 291 ARG A CZ 1 ATOM 2296 N NH1 . ARG A 1 287 ? -25.810 32.370 11.320 1.00 36.23 ? 291 ARG A NH1 1 ATOM 2297 N NH2 . ARG A 1 287 ? -26.929 30.395 11.689 1.00 35.25 ? 291 ARG A NH2 1 ATOM 2298 N N . ARG A 1 288 ? -29.316 33.554 4.383 1.00 38.48 ? 292 ARG A N 1 ATOM 2299 C CA . ARG A 1 288 ? -28.882 32.545 3.439 1.00 37.62 ? 292 ARG A CA 1 ATOM 2300 C C . ARG A 1 288 ? -27.437 32.176 3.752 1.00 37.06 ? 292 ARG A C 1 ATOM 2301 O O . ARG A 1 288 ? -26.582 33.057 3.857 1.00 37.63 ? 292 ARG A O 1 ATOM 2302 C CB . ARG A 1 288 ? -29.043 33.027 1.995 1.00 37.85 ? 292 ARG A CB 1 ATOM 2303 C CG . ARG A 1 288 ? -28.608 31.982 0.947 1.00 37.24 ? 292 ARG A CG 1 ATOM 2304 C CD . ARG A 1 288 ? -29.184 32.282 -0.410 1.00 35.79 ? 292 ARG A CD 1 ATOM 2305 N NE . ARG A 1 288 ? -30.628 32.096 -0.416 1.00 35.87 ? 292 ARG A NE 1 ATOM 2306 C CZ . ARG A 1 288 ? -31.237 30.942 -0.673 1.00 35.44 ? 292 ARG A CZ 1 ATOM 2307 N NH1 . ARG A 1 288 ? -30.525 29.860 -0.964 1.00 35.89 ? 292 ARG A NH1 1 ATOM 2308 N NH2 . ARG A 1 288 ? -32.564 30.871 -0.644 1.00 34.87 ? 292 ARG A NH2 1 ATOM 2309 N N . ILE A 1 289 ? -27.172 30.881 3.911 1.00 36.08 ? 293 ILE A N 1 ATOM 2310 C CA . ILE A 1 289 ? -25.819 30.399 4.183 1.00 35.24 ? 293 ILE A CA 1 ATOM 2311 C C . ILE A 1 289 ? -25.189 29.736 2.968 1.00 34.71 ? 293 ILE A C 1 ATOM 2312 O O . ILE A 1 289 ? -25.830 28.928 2.289 1.00 34.72 ? 293 ILE A O 1 ATOM 2313 C CB . ILE A 1 289 ? -25.788 29.443 5.400 1.00 35.44 ? 293 ILE A CB 1 ATOM 2314 C CG1 . ILE A 1 289 ? -25.715 30.259 6.681 1.00 35.64 ? 293 ILE A CG1 1 ATOM 2315 C CG2 . ILE A 1 289 ? -24.588 28.489 5.365 1.00 34.64 ? 293 ILE A CG2 1 ATOM 2316 C CD1 . ILE A 1 289 ? -27.010 30.851 7.066 1.00 36.15 ? 293 ILE A CD1 1 ATOM 2317 N N . LEU A 1 290 ? -23.927 30.084 2.721 1.00 33.90 ? 294 LEU A N 1 ATOM 2318 C CA . LEU A 1 290 ? -23.136 29.524 1.633 1.00 33.20 ? 294 LEU A CA 1 ATOM 2319 C C . LEU A 1 290 ? -22.073 28.556 2.167 1.00 33.17 ? 294 LEU A C 1 ATOM 2320 O O . LEU A 1 290 ? -21.315 28.903 3.066 1.00 33.16 ? 294 LEU A O 1 ATOM 2321 C CB . LEU A 1 290 ? -22.492 30.659 0.826 1.00 33.11 ? 294 LEU A CB 1 ATOM 2322 C CG . LEU A 1 290 ? -21.508 30.391 -0.322 1.00 32.89 ? 294 LEU A CG 1 ATOM 2323 C CD1 . LEU A 1 290 ? -22.172 29.780 -1.546 1.00 32.16 ? 294 LEU A CD1 1 ATOM 2324 C CD2 . LEU A 1 290 ? -20.797 31.674 -0.699 1.00 32.57 ? 294 LEU A CD2 1 ATOM 2325 N N . TRP A 1 291 ? -22.061 27.339 1.611 1.00 33.04 ? 295 TRP A N 1 ATOM 2326 C CA . TRP A 1 291 ? -21.051 26.311 1.858 1.00 32.64 ? 295 TRP A CA 1 ATOM 2327 C C . TRP A 1 291 ? -20.121 26.253 0.669 1.00 32.72 ? 295 TRP A C 1 ATOM 2328 O O . TRP A 1 291 ? -20.583 26.338 -0.466 1.00 32.70 ? 295 TRP A O 1 ATOM 2329 C CB . TRP A 1 291 ? -21.718 24.947 1.940 1.00 32.87 ? 295 TRP A CB 1 ATOM 2330 C CG . TRP A 1 291 ? -22.343 24.645 3.236 1.00 32.86 ? 295 TRP A CG 1 ATOM 2331 C CD1 . TRP A 1 291 ? -23.670 24.702 3.538 1.00 32.77 ? 295 TRP A CD1 1 ATOM 2332 C CD2 . TRP A 1 291 ? -21.674 24.228 4.423 1.00 32.68 ? 295 TRP A CD2 1 ATOM 2333 N NE1 . TRP A 1 291 ? -23.870 24.345 4.845 1.00 33.08 ? 295 TRP A NE1 1 ATOM 2334 C CE2 . TRP A 1 291 ? -22.656 24.056 5.414 1.00 32.92 ? 295 TRP A CE2 1 ATOM 2335 C CE3 . TRP A 1 291 ? -20.332 23.987 4.748 1.00 33.67 ? 295 TRP A CE3 1 ATOM 2336 C CZ2 . TRP A 1 291 ? -22.345 23.646 6.711 1.00 32.96 ? 295 TRP A CZ2 1 ATOM 2337 C CZ3 . TRP A 1 291 ? -20.021 23.578 6.038 1.00 33.38 ? 295 TRP A CZ3 1 ATOM 2338 C CH2 . TRP A 1 291 ? -21.026 23.406 7.002 1.00 33.24 ? 295 TRP A CH2 1 ATOM 2339 N N . GLY A 1 292 ? -18.828 26.063 0.911 1.00 32.62 ? 296 GLY A N 1 ATOM 2340 C CA . GLY A 1 292 ? -17.860 25.974 -0.177 1.00 32.84 ? 296 GLY A CA 1 ATOM 2341 C C . GLY A 1 292 ? -16.736 24.977 0.053 1.00 33.24 ? 296 GLY A C 1 ATOM 2342 O O . GLY A 1 292 ? -16.184 24.900 1.144 1.00 33.85 ? 296 GLY A O 1 ATOM 2343 N N . TRP A 1 293 ? -16.390 24.222 -0.984 1.00 33.03 ? 297 TRP A N 1 ATOM 2344 C CA . TRP A 1 293 ? -15.327 23.241 -0.919 1.00 32.75 ? 297 TRP A CA 1 ATOM 2345 C C . TRP A 1 293 ? -13.983 23.861 -1.302 1.00 32.84 ? 297 TRP A C 1 ATOM 2346 O O . TRP A 1 293 ? -13.841 24.441 -2.361 1.00 33.35 ? 297 TRP A O 1 ATOM 2347 C CB . TRP A 1 293 ? -15.675 22.052 -1.827 1.00 32.48 ? 297 TRP A CB 1 ATOM 2348 C CG . TRP A 1 293 ? -14.548 21.087 -2.094 1.00 32.47 ? 297 TRP A CG 1 ATOM 2349 C CD1 . TRP A 1 293 ? -13.726 20.493 -1.171 1.00 31.79 ? 297 TRP A CD1 1 ATOM 2350 C CD2 . TRP A 1 293 ? -14.134 20.589 -3.376 1.00 32.67 ? 297 TRP A CD2 1 ATOM 2351 N NE1 . TRP A 1 293 ? -12.822 19.673 -1.802 1.00 31.95 ? 297 TRP A NE1 1 ATOM 2352 C CE2 . TRP A 1 293 ? -13.047 19.714 -3.152 1.00 31.94 ? 297 TRP A CE2 1 ATOM 2353 C CE3 . TRP A 1 293 ? -14.578 20.797 -4.693 1.00 32.86 ? 297 TRP A CE3 1 ATOM 2354 C CZ2 . TRP A 1 293 ? -12.403 19.042 -4.192 1.00 32.36 ? 297 TRP A CZ2 1 ATOM 2355 C CZ3 . TRP A 1 293 ? -13.934 20.129 -5.731 1.00 32.32 ? 297 TRP A CZ3 1 ATOM 2356 C CH2 . TRP A 1 293 ? -12.855 19.264 -5.472 1.00 32.64 ? 297 TRP A CH2 1 ATOM 2357 N N . THR A 1 294 ? -13.002 23.731 -0.421 1.00 33.04 ? 298 THR A N 1 ATOM 2358 C CA . THR A 1 294 ? -11.625 24.117 -0.695 1.00 33.32 ? 298 THR A CA 1 ATOM 2359 C C . THR A 1 294 ? -10.781 22.852 -0.754 1.00 33.65 ? 298 THR A C 1 ATOM 2360 O O . THR A 1 294 ? -10.572 22.192 0.268 1.00 33.75 ? 298 THR A O 1 ATOM 2361 C CB . THR A 1 294 ? -11.058 25.013 0.429 1.00 33.09 ? 298 THR A CB 1 ATOM 2362 O OG1 . THR A 1 294 ? -11.968 26.080 0.694 1.00 33.81 ? 298 THR A OG1 1 ATOM 2363 C CG2 . THR A 1 294 ? -9.740 25.602 0.023 1.00 32.74 ? 298 THR A CG2 1 ATOM 2364 N N . ASN A 1 295 ? -10.298 22.503 -1.938 1.00 33.88 ? 299 ASN A N 1 ATOM 2365 C CA . ASN A 1 295 ? -9.495 21.299 -2.058 1.00 34.44 ? 299 ASN A CA 1 ATOM 2366 C C . ASN A 1 295 ? -8.039 21.544 -1.650 1.00 35.04 ? 299 ASN A C 1 ATOM 2367 O O . ASN A 1 295 ? -7.669 22.663 -1.301 1.00 35.35 ? 299 ASN A O 1 ATOM 2368 C CB . ASN A 1 295 ? -9.619 20.690 -3.461 1.00 34.37 ? 299 ASN A CB 1 ATOM 2369 C CG . ASN A 1 295 ? -8.685 21.324 -4.475 1.00 34.06 ? 299 ASN A CG 1 ATOM 2370 O OD1 . ASN A 1 295 ? -8.259 22.466 -4.332 1.00 34.26 ? 299 ASN A OD1 1 ATOM 2371 N ND2 . ASN A 1 295 ? -8.351 20.559 -5.503 1.00 34.72 ? 299 ASN A ND2 1 ATOM 2372 N N . GLU A 1 296 ? -7.220 20.498 -1.693 1.00 35.62 ? 300 GLU A N 1 ATOM 2373 C CA . GLU A 1 296 ? -5.842 20.595 -1.248 1.00 36.11 ? 300 GLU A CA 1 ATOM 2374 C C . GLU A 1 296 ? -4.975 21.291 -2.282 1.00 37.04 ? 300 GLU A C 1 ATOM 2375 O O . GLU A 1 296 ? -5.222 21.192 -3.485 1.00 36.95 ? 300 GLU A O 1 ATOM 2376 C CB . GLU A 1 296 ? -5.268 19.213 -0.936 1.00 35.69 ? 300 GLU A CB 1 ATOM 2377 C CG . GLU A 1 296 ? -6.038 18.432 0.094 1.00 34.59 ? 300 GLU A CG 1 ATOM 2378 C CD . GLU A 1 296 ? -6.092 19.118 1.440 1.00 34.34 ? 300 GLU A CD 1 ATOM 2379 O OE1 . GLU A 1 296 ? -5.032 19.233 2.103 1.00 33.08 ? 300 GLU A OE1 1 ATOM 2380 O OE2 . GLU A 1 296 ? -7.206 19.526 1.839 1.00 33.90 ? 300 GLU A OE2 1 ATOM 2381 N N . SER A 1 297 ? -3.966 22.007 -1.794 1.00 38.13 ? 301 SER A N 1 ATOM 2382 C CA . SER A 1 297 ? -2.957 22.610 -2.648 1.00 39.07 ? 301 SER A CA 1 ATOM 2383 C C . SER A 1 297 ? -1.672 21.793 -2.566 1.00 40.15 ? 301 SER A C 1 ATOM 2384 O O . SER A 1 297 ? -0.739 22.001 -3.334 1.00 40.18 ? 301 SER A O 1 ATOM 2385 C CB . SER A 1 297 ? -2.730 24.059 -2.245 1.00 38.84 ? 301 SER A CB 1 ATOM 2386 O OG . SER A 1 297 ? -3.893 24.817 -2.505 1.00 38.11 ? 301 SER A OG 1 ATOM 2387 N N . SER A 1 298 ? -1.644 20.847 -1.633 1.00 41.55 ? 302 SER A N 1 ATOM 2388 C CA . SER A 1 298 ? -0.562 19.879 -1.538 1.00 42.95 ? 302 SER A CA 1 ATOM 2389 C C . SER A 1 298 ? -0.608 18.910 -2.720 1.00 43.99 ? 302 SER A C 1 ATOM 2390 O O . SER A 1 298 ? -1.585 18.881 -3.475 1.00 43.86 ? 302 SER A O 1 ATOM 2391 C CB . SER A 1 298 ? -0.669 19.108 -0.228 1.00 42.71 ? 302 SER A CB 1 ATOM 2392 O OG . SER A 1 298 ? -1.925 18.468 -0.149 1.00 43.30 ? 302 SER A OG 1 ATOM 2393 N N . SER A 1 299 ? 0.457 18.128 -2.883 1.00 45.37 ? 303 SER A N 1 ATOM 2394 C CA . SER A 1 299 ? 0.510 17.112 -3.928 1.00 46.62 ? 303 SER A CA 1 ATOM 2395 C C . SER A 1 299 ? -0.468 15.984 -3.608 1.00 47.44 ? 303 SER A C 1 ATOM 2396 O O . SER A 1 299 ? -0.869 15.814 -2.456 1.00 47.30 ? 303 SER A O 1 ATOM 2397 C CB . SER A 1 299 ? 1.924 16.552 -4.048 1.00 46.65 ? 303 SER A CB 1 ATOM 2398 O OG . SER A 1 299 ? 2.258 15.805 -2.888 1.00 47.24 ? 303 SER A OG 1 ATOM 2399 N N . VAL A 1 300 ? -0.855 15.222 -4.629 1.00 48.67 ? 304 VAL A N 1 ATOM 2400 C CA . VAL A 1 300 ? -1.694 14.048 -4.416 1.00 50.04 ? 304 VAL A CA 1 ATOM 2401 C C . VAL A 1 300 ? -0.903 12.997 -3.624 1.00 51.02 ? 304 VAL A C 1 ATOM 2402 O O . VAL A 1 300 ? -1.479 12.243 -2.838 1.00 51.18 ? 304 VAL A O 1 ATOM 2403 C CB . VAL A 1 300 ? -2.262 13.481 -5.746 1.00 49.96 ? 304 VAL A CB 1 ATOM 2404 C CG1 . VAL A 1 300 ? -1.272 12.525 -6.425 1.00 50.26 ? 304 VAL A CG1 1 ATOM 2405 C CG2 . VAL A 1 300 ? -3.580 12.782 -5.500 1.00 50.30 ? 304 VAL A CG2 1 ATOM 2406 N N . GLU A 1 301 ? 0.419 12.983 -3.818 1.00 52.16 ? 305 GLU A N 1 ATOM 2407 C CA . GLU A 1 301 ? 1.321 12.106 -3.073 1.00 53.42 ? 305 GLU A CA 1 ATOM 2408 C C . GLU A 1 301 ? 1.151 12.304 -1.558 1.00 53.46 ? 305 GLU A C 1 ATOM 2409 O O . GLU A 1 301 ? 1.053 11.325 -0.812 1.00 53.85 ? 305 GLU A O 1 ATOM 2410 C CB . GLU A 1 301 ? 2.783 12.334 -3.505 1.00 53.45 ? 305 GLU A CB 1 ATOM 2411 C CG . GLU A 1 301 ? 3.784 11.299 -2.940 1.00 54.69 ? 305 GLU A CG 1 ATOM 2412 C CD . GLU A 1 301 ? 5.265 11.730 -3.034 1.00 54.96 ? 305 GLU A CD 1 ATOM 2413 O OE1 . GLU A 1 301 ? 5.653 12.400 -4.025 1.00 56.68 ? 305 GLU A OE1 1 ATOM 2414 O OE2 . GLU A 1 301 ? 6.047 11.379 -2.111 1.00 56.36 ? 305 GLU A OE2 1 ATOM 2415 N N . ASP A 1 302 ? 1.096 13.568 -1.120 1.00 53.59 ? 306 ASP A N 1 ATOM 2416 C CA . ASP A 1 302 ? 0.932 13.923 0.301 1.00 53.39 ? 306 ASP A CA 1 ATOM 2417 C C . ASP A 1 302 ? -0.462 13.621 0.852 1.00 53.24 ? 306 ASP A C 1 ATOM 2418 O O . ASP A 1 302 ? -0.605 13.207 2.004 1.00 53.26 ? 306 ASP A O 1 ATOM 2419 C CB . ASP A 1 302 ? 1.260 15.398 0.532 1.00 53.34 ? 306 ASP A CB 1 ATOM 2420 C CG . ASP A 1 302 ? 2.723 15.714 0.306 1.00 54.18 ? 306 ASP A CG 1 ATOM 2421 O OD1 . ASP A 1 302 ? 3.212 16.692 0.908 1.00 54.82 ? 306 ASP A OD1 1 ATOM 2422 O OD2 . ASP A 1 302 ? 3.394 14.998 -0.474 1.00 55.15 ? 306 ASP A OD2 1 ATOM 2423 N N . ASP A 1 303 ? -1.490 13.845 0.040 1.00 53.02 ? 307 ASP A N 1 ATOM 2424 C CA . ASP A 1 303 ? -2.845 13.519 0.455 1.00 52.88 ? 307 ASP A CA 1 ATOM 2425 C C . ASP A 1 303 ? -2.872 12.050 0.858 1.00 52.79 ? 307 ASP A C 1 ATOM 2426 O O . ASP A 1 303 ? -3.261 11.715 1.982 1.00 52.94 ? 307 ASP A O 1 ATOM 2427 C CB . ASP A 1 303 ? -3.864 13.796 -0.663 1.00 52.83 ? 307 ASP A CB 1 ATOM 2428 C CG . ASP A 1 303 ? -4.023 15.287 -0.978 1.00 52.70 ? 307 ASP A CG 1 ATOM 2429 O OD1 . ASP A 1 303 ? -3.538 16.141 -0.198 1.00 51.83 ? 307 ASP A OD1 1 ATOM 2430 O OD2 . ASP A 1 303 ? -4.645 15.599 -2.022 1.00 52.12 ? 307 ASP A OD2 1 ATOM 2431 N N . VAL A 1 304 ? -2.414 11.184 -0.044 1.00 52.56 ? 308 VAL A N 1 ATOM 2432 C CA . VAL A 1 304 ? -2.415 9.748 0.211 1.00 52.45 ? 308 VAL A CA 1 ATOM 2433 C C . VAL A 1 304 ? -1.691 9.413 1.524 1.00 52.49 ? 308 VAL A C 1 ATOM 2434 O O . VAL A 1 304 ? -2.152 8.557 2.288 1.00 52.44 ? 308 VAL A O 1 ATOM 2435 C CB . VAL A 1 304 ? -1.826 8.943 -0.973 1.00 52.37 ? 308 VAL A CB 1 ATOM 2436 C CG1 . VAL A 1 304 ? -1.745 7.452 -0.629 1.00 52.16 ? 308 VAL A CG1 1 ATOM 2437 C CG2 . VAL A 1 304 ? -2.661 9.149 -2.227 1.00 51.79 ? 308 VAL A CG2 1 ATOM 2438 N N . GLU A 1 305 ? -0.586 10.108 1.796 1.00 52.20 ? 309 GLU A N 1 ATOM 2439 C CA . GLU A 1 305 ? 0.193 9.836 3.000 1.00 52.18 ? 309 GLU A CA 1 ATOM 2440 C C . GLU A 1 305 ? -0.486 10.312 4.279 1.00 51.71 ? 309 GLU A C 1 ATOM 2441 O O . GLU A 1 305 ? -0.505 9.583 5.267 1.00 52.12 ? 309 GLU A O 1 ATOM 2442 C CB . GLU A 1 305 ? 1.611 10.403 2.912 1.00 52.45 ? 309 GLU A CB 1 ATOM 2443 C CG . GLU A 1 305 ? 2.553 9.782 3.953 1.00 53.98 ? 309 GLU A CG 1 ATOM 2444 C CD . GLU A 1 305 ? 3.674 10.714 4.403 1.00 56.02 ? 309 GLU A CD 1 ATOM 2445 O OE1 . GLU A 1 305 ? 4.087 10.613 5.590 1.00 56.07 ? 309 GLU A OE1 1 ATOM 2446 O OE2 . GLU A 1 305 ? 4.140 11.538 3.576 1.00 56.53 ? 309 GLU A OE2 1 ATOM 2447 N N . LYS A 1 306 ? -1.037 11.525 4.267 1.00 51.00 ? 310 LYS A N 1 ATOM 2448 C CA . LYS A 1 306 ? -1.724 12.059 5.447 1.00 49.95 ? 310 LYS A CA 1 ATOM 2449 C C . LYS A 1 306 ? -3.092 11.410 5.662 1.00 49.14 ? 310 LYS A C 1 ATOM 2450 O O . LYS A 1 306 ? -3.633 11.452 6.770 1.00 49.07 ? 310 LYS A O 1 ATOM 2451 C CB . LYS A 1 306 ? -1.820 13.595 5.407 1.00 50.14 ? 310 LYS A CB 1 ATOM 2452 C CG . LYS A 1 306 ? -2.721 14.183 4.323 1.00 50.19 ? 310 LYS A CG 1 ATOM 2453 C CD . LYS A 1 306 ? -2.574 15.701 4.243 1.00 50.10 ? 310 LYS A CD 1 ATOM 2454 C CE . LYS A 1 306 ? -3.447 16.280 3.130 1.00 50.85 ? 310 LYS A CE 1 ATOM 2455 N NZ . LYS A 1 306 ? -2.898 17.531 2.528 1.00 50.24 ? 310 LYS A NZ 1 ATOM 2456 N N . GLY A 1 307 ? -3.634 10.804 4.604 1.00 48.10 ? 311 GLY A N 1 ATOM 2457 C CA . GLY A 1 307 ? -4.851 9.992 4.702 1.00 47.00 ? 311 GLY A CA 1 ATOM 2458 C C . GLY A 1 307 ? -6.175 10.718 4.521 1.00 46.22 ? 311 GLY A C 1 ATOM 2459 O O . GLY A 1 307 ? -7.244 10.150 4.773 1.00 46.18 ? 311 GLY A O 1 ATOM 2460 N N . TRP A 1 308 ? -6.109 11.976 4.084 1.00 45.34 ? 312 TRP A N 1 ATOM 2461 C CA . TRP A 1 308 ? -7.307 12.795 3.858 1.00 44.10 ? 312 TRP A CA 1 ATOM 2462 C C . TRP A 1 308 ? -7.062 13.845 2.771 1.00 43.36 ? 312 TRP A C 1 ATOM 2463 O O . TRP A 1 308 ? -5.914 14.097 2.373 1.00 42.89 ? 312 TRP A O 1 ATOM 2464 C CB . TRP A 1 308 ? -7.778 13.449 5.166 1.00 43.89 ? 312 TRP A CB 1 ATOM 2465 C CG . TRP A 1 308 ? -6.731 14.288 5.806 1.00 43.51 ? 312 TRP A CG 1 ATOM 2466 C CD1 . TRP A 1 308 ? -5.742 13.867 6.640 1.00 43.38 ? 312 TRP A CD1 1 ATOM 2467 C CD2 . TRP A 1 308 ? -6.547 15.700 5.646 1.00 43.65 ? 312 TRP A CD2 1 ATOM 2468 N NE1 . TRP A 1 308 ? -4.954 14.927 7.024 1.00 43.41 ? 312 TRP A NE1 1 ATOM 2469 C CE2 . TRP A 1 308 ? -5.425 16.065 6.426 1.00 43.76 ? 312 TRP A CE2 1 ATOM 2470 C CE3 . TRP A 1 308 ? -7.226 16.693 4.927 1.00 42.59 ? 312 TRP A CE3 1 ATOM 2471 C CZ2 . TRP A 1 308 ? -4.967 17.382 6.510 1.00 44.03 ? 312 TRP A CZ2 1 ATOM 2472 C CZ3 . TRP A 1 308 ? -6.776 17.998 5.009 1.00 43.37 ? 312 TRP A CZ3 1 ATOM 2473 C CH2 . TRP A 1 308 ? -5.653 18.334 5.796 1.00 44.06 ? 312 TRP A CH2 1 ATOM 2474 N N . SER A 1 309 ? -8.150 14.434 2.283 1.00 42.51 ? 313 SER A N 1 ATOM 2475 C CA . SER A 1 309 ? -8.086 15.472 1.259 1.00 41.94 ? 313 SER A CA 1 ATOM 2476 C C . SER A 1 309 ? -9.369 16.282 1.267 1.00 41.64 ? 313 SER A C 1 ATOM 2477 O O . SER A 1 309 ? -10.469 15.710 1.186 1.00 41.92 ? 313 SER A O 1 ATOM 2478 C CB . SER A 1 309 ? -7.881 14.856 -0.126 1.00 41.85 ? 313 SER A CB 1 ATOM 2479 O OG . SER A 1 309 ? -7.592 15.850 -1.096 1.00 41.72 ? 313 SER A OG 1 ATOM 2480 N N . GLY A 1 310 ? -9.234 17.602 1.386 1.00 40.76 ? 314 GLY A N 1 ATOM 2481 C CA . GLY A 1 310 ? -10.374 18.496 1.236 1.00 40.19 ? 314 GLY A CA 1 ATOM 2482 C C . GLY A 1 310 ? -11.092 18.859 2.519 1.00 39.88 ? 314 GLY A C 1 ATOM 2483 O O . GLY A 1 310 ? -11.296 18.016 3.397 1.00 39.98 ? 314 GLY A O 1 ATOM 2484 N N . ILE A 1 311 ? -11.467 20.135 2.608 1.00 39.49 ? 315 ILE A N 1 ATOM 2485 C CA . ILE A 1 311 ? -12.187 20.712 3.744 1.00 38.99 ? 315 ILE A CA 1 ATOM 2486 C C . ILE A 1 311 ? -13.309 21.621 3.219 1.00 38.78 ? 315 ILE A C 1 ATOM 2487 O O . ILE A 1 311 ? -13.349 21.947 2.030 1.00 38.85 ? 315 ILE A O 1 ATOM 2488 C CB . ILE A 1 311 ? -11.249 21.528 4.670 1.00 38.99 ? 315 ILE A CB 1 ATOM 2489 C CG1 . ILE A 1 311 ? -10.600 22.688 3.915 1.00 38.95 ? 315 ILE A CG1 1 ATOM 2490 C CG2 . ILE A 1 311 ? -10.162 20.644 5.278 1.00 39.07 ? 315 ILE A CG2 1 ATOM 2491 C CD1 . ILE A 1 311 ? -10.087 23.778 4.823 1.00 39.33 ? 315 ILE A CD1 1 ATOM 2492 N N . GLN A 1 312 ? -14.236 22.003 4.085 1.00 38.16 ? 316 GLN A N 1 ATOM 2493 C CA . GLN A 1 312 ? -15.196 23.027 3.727 1.00 37.60 ? 316 GLN A CA 1 ATOM 2494 C C . GLN A 1 312 ? -14.714 24.259 4.451 1.00 37.33 ? 316 GLN A C 1 ATOM 2495 O O . GLN A 1 312 ? -14.186 24.147 5.560 1.00 37.59 ? 316 GLN A O 1 ATOM 2496 C CB . GLN A 1 312 ? -16.616 22.685 4.207 1.00 37.57 ? 316 GLN A CB 1 ATOM 2497 C CG . GLN A 1 312 ? -17.206 21.362 3.704 1.00 38.07 ? 316 GLN A CG 1 ATOM 2498 C CD . GLN A 1 312 ? -17.568 21.363 2.217 1.00 39.06 ? 316 GLN A CD 1 ATOM 2499 O OE1 . GLN A 1 312 ? -17.872 22.410 1.628 1.00 38.80 ? 316 GLN A OE1 1 ATOM 2500 N NE2 . GLN A 1 312 ? -17.544 20.173 1.605 1.00 37.62 ? 316 GLN A NE2 1 ATOM 2501 N N . THR A 1 313 ? -14.888 25.429 3.841 1.00 36.69 ? 317 THR A N 1 ATOM 2502 C CA . THR A 1 313 ? -14.714 26.691 4.554 1.00 36.21 ? 317 THR A CA 1 ATOM 2503 C C . THR A 1 313 ? -15.754 26.810 5.678 1.00 35.98 ? 317 THR A C 1 ATOM 2504 O O . THR A 1 313 ? -16.707 26.018 5.753 1.00 36.02 ? 317 THR A O 1 ATOM 2505 C CB . THR A 1 313 ? -14.895 27.900 3.615 1.00 36.20 ? 317 THR A CB 1 ATOM 2506 O OG1 . THR A 1 313 ? -16.154 27.799 2.952 1.00 36.23 ? 317 THR A OG1 1 ATOM 2507 C CG2 . THR A 1 313 ? -13.795 27.967 2.582 1.00 35.97 ? 317 THR A CG2 1 ATOM 2508 N N . ILE A 1 314 ? -15.574 27.801 6.547 1.00 35.48 ? 318 ILE A N 1 ATOM 2509 C CA . ILE A 1 314 ? -16.616 28.175 7.493 1.00 35.05 ? 318 ILE A CA 1 ATOM 2510 C C . ILE A 1 314 ? -17.799 28.698 6.672 1.00 35.05 ? 318 ILE A C 1 ATOM 2511 O O . ILE A 1 314 ? -17.601 29.476 5.747 1.00 34.86 ? 318 ILE A O 1 ATOM 2512 C CB . ILE A 1 314 ? -16.105 29.251 8.486 1.00 35.21 ? 318 ILE A CB 1 ATOM 2513 C CG1 . ILE A 1 314 ? -14.752 28.839 9.107 1.00 34.58 ? 318 ILE A CG1 1 ATOM 2514 C CG2 . ILE A 1 314 ? -17.180 29.621 9.537 1.00 34.53 ? 318 ILE A CG2 1 ATOM 2515 C CD1 . ILE A 1 314 ? -14.727 27.474 9.823 1.00 34.23 ? 318 ILE A CD1 1 ATOM 2516 N N . PRO A 1 315 ? -19.027 28.240 6.975 1.00 35.27 ? 319 PRO A N 1 ATOM 2517 C CA . PRO A 1 315 ? -20.185 28.637 6.171 1.00 35.43 ? 319 PRO A CA 1 ATOM 2518 C C . PRO A 1 315 ? -20.469 30.113 6.316 1.00 35.59 ? 319 PRO A C 1 ATOM 2519 O O . PRO A 1 315 ? -20.433 30.636 7.426 1.00 35.65 ? 319 PRO A O 1 ATOM 2520 C CB . PRO A 1 315 ? -21.335 27.828 6.780 1.00 35.68 ? 319 PRO A CB 1 ATOM 2521 C CG . PRO A 1 315 ? -20.680 26.750 7.591 1.00 35.55 ? 319 PRO A CG 1 ATOM 2522 C CD . PRO A 1 315 ? -19.407 27.329 8.070 1.00 35.32 ? 319 PRO A CD 1 ATOM 2523 N N . ARG A 1 316 ? -20.739 30.796 5.211 1.00 35.92 ? 320 ARG A N 1 ATOM 2524 C CA . ARG A 1 316 ? -20.935 32.240 5.308 1.00 36.35 ? 320 ARG A CA 1 ATOM 2525 C C . ARG A 1 316 ? -22.350 32.724 5.099 1.00 36.70 ? 320 ARG A C 1 ATOM 2526 O O . ARG A 1 316 ? -23.109 32.158 4.321 1.00 36.64 ? 320 ARG A O 1 ATOM 2527 C CB . ARG A 1 316 ? -19.939 33.049 4.461 1.00 36.19 ? 320 ARG A CB 1 ATOM 2528 C CG . ARG A 1 316 ? -19.227 32.326 3.361 1.00 35.73 ? 320 ARG A CG 1 ATOM 2529 C CD . ARG A 1 316 ? -17.735 32.541 3.516 1.00 35.00 ? 320 ARG A CD 1 ATOM 2530 N NE . ARG A 1 316 ? -17.060 32.708 2.233 1.00 37.35 ? 320 ARG A NE 1 ATOM 2531 C CZ . ARG A 1 316 ? -15.782 32.415 1.999 1.00 37.97 ? 320 ARG A CZ 1 ATOM 2532 N NH1 . ARG A 1 316 ? -15.015 31.913 2.956 1.00 38.68 ? 320 ARG A NH1 1 ATOM 2533 N NH2 . ARG A 1 316 ? -15.265 32.619 0.797 1.00 38.58 ? 320 ARG A NH2 1 ATOM 2534 N N . LYS A 1 317 ? -22.697 33.766 5.846 1.00 37.46 ? 321 LYS A N 1 ATOM 2535 C CA . LYS A 1 317 ? -23.920 34.510 5.607 1.00 38.06 ? 321 LYS A CA 1 ATOM 2536 C C . LYS A 1 317 ? -23.669 35.308 4.345 1.00 38.37 ? 321 LYS A C 1 ATOM 2537 O O . LYS A 1 317 ? -22.566 35.847 4.142 1.00 37.98 ? 321 LYS A O 1 ATOM 2538 C CB . LYS A 1 317 ? -24.244 35.441 6.783 1.00 38.17 ? 321 LYS A CB 1 ATOM 2539 C CG . LYS A 1 317 ? -25.654 36.011 6.747 1.00 38.24 ? 321 LYS A CG 1 ATOM 2540 C CD . LYS A 1 317 ? -25.900 36.991 7.877 1.00 38.17 ? 321 LYS A CD 1 ATOM 2541 C CE . LYS A 1 317 ? -27.137 37.831 7.579 1.00 39.16 ? 321 LYS A CE 1 ATOM 2542 N NZ . LYS A 1 317 ? -27.572 38.744 8.682 1.00 39.58 ? 321 LYS A NZ 1 ATOM 2543 N N . ILE A 1 318 ? -24.688 35.365 3.498 1.00 38.88 ? 322 ILE A N 1 ATOM 2544 C CA . ILE A 1 318 ? -24.559 35.995 2.202 1.00 39.77 ? 322 ILE A CA 1 ATOM 2545 C C . ILE A 1 318 ? -25.761 36.894 1.925 1.00 40.13 ? 322 ILE A C 1 ATOM 2546 O O . ILE A 1 318 ? -26.904 36.465 2.085 1.00 40.54 ? 322 ILE A O 1 ATOM 2547 C CB . ILE A 1 318 ? -24.359 34.921 1.095 1.00 39.88 ? 322 ILE A CB 1 ATOM 2548 C CG1 . ILE A 1 318 ? -23.764 35.541 -0.159 1.00 40.19 ? 322 ILE A CG1 1 ATOM 2549 C CG2 . ILE A 1 318 ? -25.665 34.166 0.785 1.00 39.95 ? 322 ILE A CG2 1 ATOM 2550 C CD1 . ILE A 1 318 ? -23.338 34.521 -1.173 1.00 40.84 ? 322 ILE A CD1 1 ATOM 2551 N N . TRP A 1 319 ? -25.499 38.140 1.530 1.00 40.66 ? 323 TRP A N 1 ATOM 2552 C CA . TRP A 1 319 ? -26.562 39.100 1.170 1.00 41.06 ? 323 TRP A CA 1 ATOM 2553 C C . TRP A 1 319 ? -26.119 40.065 0.056 1.00 41.19 ? 323 TRP A C 1 ATOM 2554 O O . TRP A 1 319 ? -24.955 40.062 -0.330 1.00 41.48 ? 323 TRP A O 1 ATOM 2555 C CB . TRP A 1 319 ? -27.040 39.865 2.411 1.00 41.18 ? 323 TRP A CB 1 ATOM 2556 C CG . TRP A 1 319 ? -26.003 40.776 3.025 1.00 42.07 ? 323 TRP A CG 1 ATOM 2557 C CD1 . TRP A 1 319 ? -25.858 42.124 2.808 1.00 42.23 ? 323 TRP A CD1 1 ATOM 2558 C CD2 . TRP A 1 319 ? -24.966 40.408 3.948 1.00 41.97 ? 323 TRP A CD2 1 ATOM 2559 N NE1 . TRP A 1 319 ? -24.793 42.609 3.534 1.00 41.99 ? 323 TRP A NE1 1 ATOM 2560 C CE2 . TRP A 1 319 ? -24.234 41.583 4.248 1.00 41.76 ? 323 TRP A CE2 1 ATOM 2561 C CE3 . TRP A 1 319 ? -24.578 39.200 4.542 1.00 41.81 ? 323 TRP A CE3 1 ATOM 2562 C CZ2 . TRP A 1 319 ? -23.146 41.588 5.123 1.00 41.83 ? 323 TRP A CZ2 1 ATOM 2563 C CZ3 . TRP A 1 319 ? -23.487 39.205 5.418 1.00 42.07 ? 323 TRP A CZ3 1 ATOM 2564 C CH2 . TRP A 1 319 ? -22.784 40.393 5.694 1.00 41.97 ? 323 TRP A CH2 1 ATOM 2565 N N . LEU A 1 320 ? -27.040 40.880 -0.459 1.00 41.58 ? 324 LEU A N 1 ATOM 2566 C CA . LEU A 1 320 ? -26.719 41.862 -1.510 1.00 41.98 ? 324 LEU A CA 1 ATOM 2567 C C . LEU A 1 320 ? -26.111 43.149 -0.930 1.00 42.76 ? 324 LEU A C 1 ATOM 2568 O O . LEU A 1 320 ? -26.614 43.695 0.058 1.00 43.07 ? 324 LEU A O 1 ATOM 2569 C CB . LEU A 1 320 ? -27.976 42.228 -2.304 1.00 41.74 ? 324 LEU A CB 1 ATOM 2570 C CG . LEU A 1 320 ? -28.054 42.412 -3.833 1.00 40.65 ? 324 LEU A CG 1 ATOM 2571 C CD1 . LEU A 1 320 ? -28.687 43.748 -4.148 1.00 39.54 ? 324 LEU A CD1 1 ATOM 2572 C CD2 . LEU A 1 320 ? -26.734 42.265 -4.566 1.00 39.72 ? 324 LEU A CD2 1 ATOM 2573 N N . ASP A 1 321 ? -25.036 43.632 -1.546 1.00 43.47 ? 325 ASP A N 1 ATOM 2574 C CA . ASP A 1 321 ? -24.416 44.896 -1.154 1.00 44.35 ? 325 ASP A CA 1 ATOM 2575 C C . ASP A 1 321 ? -25.339 46.062 -1.561 1.00 44.67 ? 325 ASP A C 1 ATOM 2576 O O . ASP A 1 321 ? -26.115 45.929 -2.508 1.00 44.44 ? 325 ASP A O 1 ATOM 2577 C CB . ASP A 1 321 ? -23.024 44.982 -1.799 1.00 44.65 ? 325 ASP A CB 1 ATOM 2578 C CG . ASP A 1 321 ? -22.391 46.357 -1.685 1.00 46.04 ? 325 ASP A CG 1 ATOM 2579 O OD1 . ASP A 1 321 ? -22.729 47.229 -2.517 1.00 46.70 ? 325 ASP A OD1 1 ATOM 2580 O OD2 . ASP A 1 321 ? -21.537 46.562 -0.786 1.00 47.93 ? 325 ASP A OD2 1 ATOM 2581 N N . ARG A 1 322 ? -25.265 47.186 -0.846 1.00 45.32 ? 326 ARG A N 1 ATOM 2582 C CA . ARG A 1 322 ? -26.139 48.347 -1.120 1.00 46.38 ? 326 ARG A CA 1 ATOM 2583 C C . ARG A 1 322 ? -26.110 48.865 -2.559 1.00 46.15 ? 326 ARG A C 1 ATOM 2584 O O . ARG A 1 322 ? -27.138 49.263 -3.096 1.00 46.09 ? 326 ARG A O 1 ATOM 2585 C CB . ARG A 1 322 ? -25.850 49.512 -0.173 1.00 46.91 ? 326 ARG A CB 1 ATOM 2586 C CG . ARG A 1 322 ? -26.798 49.599 1.020 1.00 49.81 ? 326 ARG A CG 1 ATOM 2587 C CD . ARG A 1 322 ? -27.441 51.002 1.139 1.00 54.39 ? 326 ARG A CD 1 ATOM 2588 N NE . ARG A 1 322 ? -28.901 50.951 0.969 1.00 57.21 ? 326 ARG A NE 1 ATOM 2589 C CZ . ARG A 1 322 ? -29.754 51.904 1.351 1.00 58.58 ? 326 ARG A CZ 1 ATOM 2590 N NH1 . ARG A 1 322 ? -29.315 53.023 1.930 1.00 59.26 ? 326 ARG A NH1 1 ATOM 2591 N NH2 . ARG A 1 322 ? -31.058 51.736 1.157 1.00 58.97 ? 326 ARG A NH2 1 ATOM 2592 N N . SER A 1 323 ? -24.930 48.875 -3.166 1.00 46.13 ? 327 SER A N 1 ATOM 2593 C CA . SER A 1 323 ? -24.777 49.257 -4.566 1.00 46.27 ? 327 SER A CA 1 ATOM 2594 C C . SER A 1 323 ? -25.571 48.320 -5.488 1.00 45.87 ? 327 SER A C 1 ATOM 2595 O O . SER A 1 323 ? -26.023 48.716 -6.567 1.00 45.90 ? 327 SER A O 1 ATOM 2596 C CB . SER A 1 323 ? -23.287 49.264 -4.964 1.00 46.45 ? 327 SER A CB 1 ATOM 2597 O OG . SER A 1 323 ? -22.830 47.956 -5.325 1.00 47.84 ? 327 SER A OG 1 ATOM 2598 N N . GLY A 1 324 ? -25.723 47.072 -5.060 1.00 45.45 ? 328 GLY A N 1 ATOM 2599 C CA . GLY A 1 324 ? -26.457 46.082 -5.837 1.00 44.91 ? 328 GLY A CA 1 ATOM 2600 C C . GLY A 1 324 ? -25.647 45.460 -6.957 1.00 44.32 ? 328 GLY A C 1 ATOM 2601 O O . GLY A 1 324 ? -26.198 44.759 -7.800 1.00 44.23 ? 328 GLY A O 1 ATOM 2602 N N . LYS A 1 325 ? -24.341 45.710 -6.966 1.00 43.74 ? 329 LYS A N 1 ATOM 2603 C CA . LYS A 1 325 ? -23.476 45.170 -8.012 1.00 43.41 ? 329 LYS A CA 1 ATOM 2604 C C . LYS A 1 325 ? -22.783 43.863 -7.598 1.00 41.95 ? 329 LYS A C 1 ATOM 2605 O O . LYS A 1 325 ? -22.253 43.150 -8.452 1.00 42.14 ? 329 LYS A O 1 ATOM 2606 C CB . LYS A 1 325 ? -22.441 46.211 -8.466 1.00 43.37 ? 329 LYS A CB 1 ATOM 2607 C CG . LYS A 1 325 ? -23.041 47.472 -9.084 1.00 44.86 ? 329 LYS A CG 1 ATOM 2608 C CD . LYS A 1 325 ? -21.998 48.598 -9.264 1.00 45.37 ? 329 LYS A CD 1 ATOM 2609 C CE . LYS A 1 325 ? -21.360 49.038 -7.915 1.00 48.18 ? 329 LYS A CE 1 ATOM 2610 N NZ . LYS A 1 325 ? -21.043 50.511 -7.813 1.00 48.82 ? 329 LYS A NZ 1 ATOM 2611 N N . GLN A 1 326 ? -22.799 43.544 -6.306 1.00 40.20 ? 330 GLN A N 1 ATOM 2612 C CA . GLN A 1 326 ? -22.111 42.356 -5.806 1.00 38.62 ? 330 GLN A CA 1 ATOM 2613 C C . GLN A 1 326 ? -22.725 41.825 -4.519 1.00 37.96 ? 330 GLN A C 1 ATOM 2614 O O . GLN A 1 326 ? -23.485 42.525 -3.841 1.00 37.39 ? 330 GLN A O 1 ATOM 2615 C CB . GLN A 1 326 ? -20.625 42.644 -5.572 1.00 38.49 ? 330 GLN A CB 1 ATOM 2616 C CG . GLN A 1 326 ? -20.324 43.362 -4.254 1.00 37.04 ? 330 GLN A CG 1 ATOM 2617 C CD . GLN A 1 326 ? -18.862 43.327 -3.893 1.00 35.33 ? 330 GLN A CD 1 ATOM 2618 O OE1 . GLN A 1 326 ? -18.064 44.108 -4.408 1.00 34.73 ? 330 GLN A OE1 1 ATOM 2619 N NE2 . GLN A 1 326 ? -18.499 42.425 -2.989 1.00 34.72 ? 330 GLN A NE2 1 ATOM 2620 N N . LEU A 1 327 ? -22.371 40.582 -4.191 1.00 37.30 ? 331 LEU A N 1 ATOM 2621 C CA . LEU A 1 327 ? -22.781 39.953 -2.936 1.00 36.57 ? 331 LEU A CA 1 ATOM 2622 C C . LEU A 1 327 ? -21.739 40.165 -1.854 1.00 36.58 ? 331 LEU A C 1 ATOM 2623 O O . LEU A 1 327 ? -20.540 40.279 -2.136 1.00 36.43 ? 331 LEU A O 1 ATOM 2624 C CB . LEU A 1 327 ? -23.025 38.453 -3.123 1.00 36.08 ? 331 LEU A CB 1 ATOM 2625 C CG . LEU A 1 327 ? -24.156 38.033 -4.059 1.00 34.56 ? 331 LEU A CG 1 ATOM 2626 C CD1 . LEU A 1 327 ? -24.140 36.536 -4.224 1.00 33.36 ? 331 LEU A CD1 1 ATOM 2627 C CD2 . LEU A 1 327 ? -25.489 38.489 -3.522 1.00 33.44 ? 331 LEU A CD2 1 ATOM 2628 N N . ILE A 1 328 ? -22.210 40.222 -0.614 1.00 36.58 ? 332 ILE A N 1 ATOM 2629 C CA . ILE A 1 328 ? -21.331 40.268 0.551 1.00 36.53 ? 332 ILE A CA 1 ATOM 2630 C C . ILE A 1 328 ? -21.409 38.949 1.329 1.00 36.23 ? 332 ILE A C 1 ATOM 2631 O O . ILE A 1 328 ? -22.502 38.432 1.578 1.00 36.04 ? 332 ILE A O 1 ATOM 2632 C CB . ILE A 1 328 ? -21.678 41.452 1.476 1.00 36.65 ? 332 ILE A CB 1 ATOM 2633 C CG1 . ILE A 1 328 ? -21.707 42.752 0.668 1.00 36.67 ? 332 ILE A CG1 1 ATOM 2634 C CG2 . ILE A 1 328 ? -20.682 41.530 2.640 1.00 36.93 ? 332 ILE A CG2 1 ATOM 2635 C CD1 . ILE A 1 328 ? -21.805 44.006 1.513 1.00 38.78 ? 332 ILE A CD1 1 ATOM 2636 N N . GLN A 1 329 ? -20.243 38.412 1.686 1.00 35.94 ? 333 GLN A N 1 ATOM 2637 C CA . GLN A 1 329 ? -20.151 37.212 2.519 1.00 35.81 ? 333 GLN A CA 1 ATOM 2638 C C . GLN A 1 329 ? -19.458 37.507 3.839 1.00 35.90 ? 333 GLN A C 1 ATOM 2639 O O . GLN A 1 329 ? -18.573 38.368 3.921 1.00 35.95 ? 333 GLN A O 1 ATOM 2640 C CB . GLN A 1 329 ? -19.386 36.111 1.804 1.00 35.72 ? 333 GLN A CB 1 ATOM 2641 C CG . GLN A 1 329 ? -19.996 35.685 0.491 1.00 35.70 ? 333 GLN A CG 1 ATOM 2642 C CD . GLN A 1 329 ? -18.956 35.103 -0.424 1.00 36.31 ? 333 GLN A CD 1 ATOM 2643 O OE1 . GLN A 1 329 ? -18.444 33.994 -0.197 1.00 36.02 ? 333 GLN A OE1 1 ATOM 2644 N NE2 . GLN A 1 329 ? -18.609 35.858 -1.462 1.00 35.77 ? 333 GLN A NE2 1 ATOM 2645 N N . TRP A 1 330 ? -19.861 36.780 4.874 1.00 35.73 ? 334 TRP A N 1 ATOM 2646 C CA . TRP A 1 330 ? -19.272 36.929 6.195 1.00 35.47 ? 334 TRP A CA 1 ATOM 2647 C C . TRP A 1 330 ? -19.499 35.635 6.958 1.00 35.94 ? 334 TRP A C 1 ATOM 2648 O O . TRP A 1 330 ? -20.637 35.144 7.016 1.00 35.94 ? 334 TRP A O 1 ATOM 2649 C CB . TRP A 1 330 ? -19.918 38.098 6.933 1.00 34.75 ? 334 TRP A CB 1 ATOM 2650 C CG . TRP A 1 330 ? -19.118 38.622 8.088 1.00 34.46 ? 334 TRP A CG 1 ATOM 2651 C CD1 . TRP A 1 330 ? -19.448 38.560 9.412 1.00 33.32 ? 334 TRP A CD1 1 ATOM 2652 C CD2 . TRP A 1 330 ? -17.857 39.309 8.021 1.00 34.39 ? 334 TRP A CD2 1 ATOM 2653 N NE1 . TRP A 1 330 ? -18.477 39.164 10.172 1.00 32.40 ? 334 TRP A NE1 1 ATOM 2654 C CE2 . TRP A 1 330 ? -17.487 39.629 9.346 1.00 33.43 ? 334 TRP A CE2 1 ATOM 2655 C CE3 . TRP A 1 330 ? -17.003 39.684 6.968 1.00 33.64 ? 334 TRP A CE3 1 ATOM 2656 C CZ2 . TRP A 1 330 ? -16.303 40.300 9.649 1.00 33.25 ? 334 TRP A CZ2 1 ATOM 2657 C CZ3 . TRP A 1 330 ? -15.833 40.346 7.271 1.00 33.08 ? 334 TRP A CZ3 1 ATOM 2658 C CH2 . TRP A 1 330 ? -15.494 40.649 8.600 1.00 33.75 ? 334 TRP A CH2 1 ATOM 2659 N N . PRO A 1 331 ? -18.419 35.065 7.531 1.00 36.29 ? 335 PRO A N 1 ATOM 2660 C CA . PRO A 1 331 ? -18.496 33.818 8.289 1.00 36.79 ? 335 PRO A CA 1 ATOM 2661 C C . PRO A 1 331 ? -19.656 33.850 9.283 1.00 37.16 ? 335 PRO A C 1 ATOM 2662 O O . PRO A 1 331 ? -19.821 34.853 9.989 1.00 37.33 ? 335 PRO A O 1 ATOM 2663 C CB . PRO A 1 331 ? -17.162 33.795 9.033 1.00 36.62 ? 335 PRO A CB 1 ATOM 2664 C CG . PRO A 1 331 ? -16.247 34.504 8.133 1.00 36.20 ? 335 PRO A CG 1 ATOM 2665 C CD . PRO A 1 331 ? -17.043 35.586 7.488 1.00 36.17 ? 335 PRO A CD 1 ATOM 2666 N N . VAL A 1 332 ? -20.465 32.788 9.329 1.00 37.60 ? 336 VAL A N 1 ATOM 2667 C CA . VAL A 1 332 ? -21.602 32.760 10.257 1.00 38.13 ? 336 VAL A CA 1 ATOM 2668 C C . VAL A 1 332 ? -21.132 33.275 11.602 1.00 38.94 ? 336 VAL A C 1 ATOM 2669 O O . VAL A 1 332 ? -20.008 32.995 12.026 1.00 39.26 ? 336 VAL A O 1 ATOM 2670 C CB . VAL A 1 332 ? -22.237 31.362 10.438 1.00 37.81 ? 336 VAL A CB 1 ATOM 2671 C CG1 . VAL A 1 332 ? -23.226 31.069 9.324 1.00 37.02 ? 336 VAL A CG1 1 ATOM 2672 C CG2 . VAL A 1 332 ? -21.164 30.273 10.565 1.00 37.69 ? 336 VAL A CG2 1 ATOM 2673 N N . ARG A 1 333 ? -21.976 34.040 12.275 1.00 39.65 ? 337 ARG A N 1 ATOM 2674 C CA . ARG A 1 333 ? -21.555 34.633 13.538 1.00 40.47 ? 337 ARG A CA 1 ATOM 2675 C C . ARG A 1 333 ? -21.248 33.613 14.647 1.00 40.31 ? 337 ARG A C 1 ATOM 2676 O O . ARG A 1 333 ? -20.484 33.912 15.568 1.00 40.30 ? 337 ARG A O 1 ATOM 2677 C CB . ARG A 1 333 ? -22.528 35.737 13.971 1.00 40.71 ? 337 ARG A CB 1 ATOM 2678 C CG . ARG A 1 333 ? -22.573 36.879 12.931 1.00 43.21 ? 337 ARG A CG 1 ATOM 2679 C CD . ARG A 1 333 ? -22.785 38.254 13.542 1.00 46.28 ? 337 ARG A CD 1 ATOM 2680 N NE . ARG A 1 333 ? -21.805 38.570 14.585 1.00 48.02 ? 337 ARG A NE 1 ATOM 2681 C CZ . ARG A 1 333 ? -21.916 39.593 15.433 1.00 48.55 ? 337 ARG A CZ 1 ATOM 2682 N NH1 . ARG A 1 333 ? -22.959 40.421 15.363 1.00 48.48 ? 337 ARG A NH1 1 ATOM 2683 N NH2 . ARG A 1 333 ? -20.977 39.798 16.351 1.00 47.97 ? 337 ARG A NH2 1 ATOM 2684 N N . GLU A 1 334 ? -21.802 32.401 14.522 1.00 40.17 ? 338 GLU A N 1 ATOM 2685 C CA . GLU A 1 334 ? -21.545 31.317 15.478 1.00 40.13 ? 338 GLU A CA 1 ATOM 2686 C C . GLU A 1 334 ? -20.064 30.971 15.634 1.00 40.03 ? 338 GLU A C 1 ATOM 2687 O O . GLU A 1 334 ? -19.649 30.584 16.717 1.00 40.41 ? 338 GLU A O 1 ATOM 2688 C CB . GLU A 1 334 ? -22.319 30.039 15.127 1.00 40.06 ? 338 GLU A CB 1 ATOM 2689 C CG . GLU A 1 334 ? -23.798 30.055 15.453 1.00 40.32 ? 338 GLU A CG 1 ATOM 2690 C CD . GLU A 1 334 ? -24.648 30.684 14.351 1.00 41.24 ? 338 GLU A CD 1 ATOM 2691 O OE1 . GLU A 1 334 ? -24.070 31.194 13.363 1.00 40.93 ? 338 GLU A OE1 1 ATOM 2692 O OE2 . GLU A 1 334 ? -25.900 30.670 14.474 1.00 41.31 ? 338 GLU A OE2 1 ATOM 2693 N N . VAL A 1 335 ? -19.265 31.101 14.575 1.00 39.59 ? 339 VAL A N 1 ATOM 2694 C CA . VAL A 1 335 ? -17.851 30.743 14.680 1.00 39.30 ? 339 VAL A CA 1 ATOM 2695 C C . VAL A 1 335 ? -17.141 31.626 15.700 1.00 39.69 ? 339 VAL A C 1 ATOM 2696 O O . VAL A 1 335 ? -16.040 31.312 16.147 1.00 39.68 ? 339 VAL A O 1 ATOM 2697 C CB . VAL A 1 335 ? -17.115 30.736 13.301 1.00 39.11 ? 339 VAL A CB 1 ATOM 2698 C CG1 . VAL A 1 335 ? -16.715 32.139 12.859 1.00 38.67 ? 339 VAL A CG1 1 ATOM 2699 C CG2 . VAL A 1 335 ? -15.901 29.812 13.345 1.00 38.14 ? 339 VAL A CG2 1 ATOM 2700 N N . GLU A 1 336 ? -17.786 32.726 16.074 1.00 40.30 ? 340 GLU A N 1 ATOM 2701 C CA . GLU A 1 336 ? -17.185 33.687 16.999 1.00 41.24 ? 340 GLU A CA 1 ATOM 2702 C C . GLU A 1 336 ? -17.176 33.148 18.431 1.00 41.25 ? 340 GLU A C 1 ATOM 2703 O O . GLU A 1 336 ? -16.394 33.584 19.267 1.00 41.31 ? 340 GLU A O 1 ATOM 2704 C CB . GLU A 1 336 ? -17.857 35.061 16.882 1.00 40.73 ? 340 GLU A CB 1 ATOM 2705 C CG . GLU A 1 336 ? -17.581 35.736 15.531 1.00 41.72 ? 340 GLU A CG 1 ATOM 2706 C CD . GLU A 1 336 ? -18.317 37.055 15.331 1.00 42.49 ? 340 GLU A CD 1 ATOM 2707 O OE1 . GLU A 1 336 ? -18.691 37.697 16.336 1.00 45.60 ? 340 GLU A OE1 1 ATOM 2708 O OE2 . GLU A 1 336 ? -18.525 37.459 14.163 1.00 43.94 ? 340 GLU A OE2 1 ATOM 2709 N N . ARG A 1 337 ? -18.016 32.151 18.673 1.00 41.73 ? 341 ARG A N 1 ATOM 2710 C CA . ARG A 1 337 ? -18.078 31.453 19.951 1.00 42.23 ? 341 ARG A CA 1 ATOM 2711 C C . ARG A 1 337 ? -16.795 30.698 20.282 1.00 43.07 ? 341 ARG A C 1 ATOM 2712 O O . ARG A 1 337 ? -16.502 30.464 21.452 1.00 43.24 ? 341 ARG A O 1 ATOM 2713 C CB . ARG A 1 337 ? -19.251 30.473 19.953 1.00 41.86 ? 341 ARG A CB 1 ATOM 2714 C CG . ARG A 1 337 ? -20.595 31.129 19.798 1.00 40.49 ? 341 ARG A CG 1 ATOM 2715 C CD . ARG A 1 337 ? -21.676 30.102 19.703 1.00 39.05 ? 341 ARG A CD 1 ATOM 2716 N NE . ARG A 1 337 ? -22.970 30.753 19.571 1.00 39.40 ? 341 ARG A NE 1 ATOM 2717 C CZ . ARG A 1 337 ? -24.098 30.128 19.263 1.00 39.45 ? 341 ARG A CZ 1 ATOM 2718 N NH1 . ARG A 1 337 ? -24.095 28.816 19.054 1.00 40.48 ? 341 ARG A NH1 1 ATOM 2719 N NH2 . ARG A 1 337 ? -25.226 30.817 19.156 1.00 38.60 ? 341 ARG A NH2 1 ATOM 2720 N N . LEU A 1 338 ? -16.049 30.309 19.249 1.00 44.10 ? 342 LEU A N 1 ATOM 2721 C CA . LEU A 1 338 ? -14.804 29.572 19.411 1.00 45.11 ? 342 LEU A CA 1 ATOM 2722 C C . LEU A 1 338 ? -13.681 30.465 19.897 1.00 46.38 ? 342 LEU A C 1 ATOM 2723 O O . LEU A 1 338 ? -12.596 29.978 20.236 1.00 46.70 ? 342 LEU A O 1 ATOM 2724 C CB . LEU A 1 338 ? -14.382 28.942 18.091 1.00 44.73 ? 342 LEU A CB 1 ATOM 2725 C CG . LEU A 1 338 ? -15.208 27.786 17.543 1.00 44.57 ? 342 LEU A CG 1 ATOM 2726 C CD1 . LEU A 1 338 ? -14.828 27.560 16.102 1.00 44.60 ? 342 LEU A CD1 1 ATOM 2727 C CD2 . LEU A 1 338 ? -14.991 26.531 18.348 1.00 44.17 ? 342 LEU A CD2 1 ATOM 2728 N N . ARG A 1 339 ? -13.928 31.773 19.910 1.00 47.73 ? 343 ARG A N 1 ATOM 2729 C CA . ARG A 1 339 ? -12.915 32.732 20.329 1.00 49.13 ? 343 ARG A CA 1 ATOM 2730 C C . ARG A 1 339 ? -12.575 32.529 21.799 1.00 50.00 ? 343 ARG A C 1 ATOM 2731 O O . ARG A 1 339 ? -13.467 32.284 22.614 1.00 50.20 ? 343 ARG A O 1 ATOM 2732 C CB . ARG A 1 339 ? -13.408 34.162 20.100 1.00 49.15 ? 343 ARG A CB 1 ATOM 2733 C CG . ARG A 1 339 ? -13.360 34.622 18.657 1.00 49.82 ? 343 ARG A CG 1 ATOM 2734 C CD . ARG A 1 339 ? -14.057 35.958 18.484 1.00 50.36 ? 343 ARG A CD 1 ATOM 2735 N NE . ARG A 1 339 ? -13.841 36.490 17.141 1.00 51.96 ? 343 ARG A NE 1 ATOM 2736 C CZ . ARG A 1 339 ? -14.456 37.559 16.636 1.00 52.65 ? 343 ARG A CZ 1 ATOM 2737 N NH1 . ARG A 1 339 ? -15.344 38.230 17.356 1.00 52.85 ? 343 ARG A NH1 1 ATOM 2738 N NH2 . ARG A 1 339 ? -14.184 37.961 15.400 1.00 52.41 ? 343 ARG A NH2 1 ATOM 2739 N N . THR A 1 340 ? -11.292 32.619 22.134 1.00 51.09 ? 344 THR A N 1 ATOM 2740 C CA . THR A 1 340 ? -10.878 32.677 23.531 1.00 52.63 ? 344 THR A CA 1 ATOM 2741 C C . THR A 1 340 ? -11.439 33.937 24.203 1.00 53.71 ? 344 THR A C 1 ATOM 2742 O O . THR A 1 340 ? -11.912 34.843 23.513 1.00 54.01 ? 344 THR A O 1 ATOM 2743 C CB . THR A 1 340 ? -9.360 32.677 23.675 1.00 52.53 ? 344 THR A CB 1 ATOM 2744 O OG1 . THR A 1 340 ? -9.041 32.641 25.065 1.00 53.80 ? 344 THR A OG1 1 ATOM 2745 C CG2 . THR A 1 340 ? -8.742 33.945 23.070 1.00 52.42 ? 344 THR A CG2 1 ATOM 2746 N N . LYS A 1 341 ? -11.389 33.995 25.535 1.00 55.08 ? 345 LYS A N 1 ATOM 2747 C CA . LYS A 1 341 ? -11.848 35.189 26.276 1.00 56.42 ? 345 LYS A CA 1 ATOM 2748 C C . LYS A 1 341 ? -10.829 36.334 26.165 1.00 56.77 ? 345 LYS A C 1 ATOM 2749 O O . LYS A 1 341 ? -11.193 37.471 25.844 1.00 56.58 ? 345 LYS A O 1 ATOM 2750 C CB . LYS A 1 341 ? -12.098 34.885 27.761 1.00 56.83 ? 345 LYS A CB 1 ATOM 2751 C CG . LYS A 1 341 ? -12.330 33.414 28.127 1.00 58.40 ? 345 LYS A CG 1 ATOM 2752 C CD . LYS A 1 341 ? -13.758 33.142 28.581 1.00 60.03 ? 345 LYS A CD 1 ATOM 2753 C CE . LYS A 1 341 ? -13.807 31.871 29.440 1.00 61.33 ? 345 LYS A CE 1 ATOM 2754 N NZ . LYS A 1 341 ? -15.165 31.231 29.457 1.00 62.36 ? 345 LYS A NZ 1 ATOM 2755 N N . GLN A 1 342 ? -9.559 36.023 26.432 1.00 57.45 ? 346 GLN A N 1 ATOM 2756 C CA . GLN A 1 342 ? -8.480 37.017 26.362 1.00 58.35 ? 346 GLN A CA 1 ATOM 2757 C C . GLN A 1 342 ? -8.139 37.439 24.933 1.00 58.33 ? 346 GLN A C 1 ATOM 2758 O O . GLN A 1 342 ? -7.441 36.728 24.205 1.00 58.55 ? 346 GLN A O 1 ATOM 2759 C CB . GLN A 1 342 ? -7.221 36.548 27.117 1.00 58.59 ? 346 GLN A CB 1 ATOM 2760 C CG . GLN A 1 342 ? -6.969 37.284 28.458 1.00 60.21 ? 346 GLN A CG 1 ATOM 2761 C CD . GLN A 1 342 ? -8.104 37.103 29.495 1.00 62.15 ? 346 GLN A CD 1 ATOM 2762 O OE1 . GLN A 1 342 ? -8.400 35.978 29.932 1.00 62.40 ? 346 GLN A OE1 1 ATOM 2763 N NE2 . GLN A 1 342 ? -8.730 38.220 29.895 1.00 61.56 ? 346 GLN A NE2 1 ATOM 2764 N N . VAL A 1 343 ? -8.648 38.603 24.545 1.00 58.36 ? 347 VAL A N 1 ATOM 2765 C CA . VAL A 1 343 ? -8.399 39.163 23.219 1.00 58.39 ? 347 VAL A CA 1 ATOM 2766 C C . VAL A 1 343 ? -7.091 39.946 23.201 1.00 58.30 ? 347 VAL A C 1 ATOM 2767 O O . VAL A 1 343 ? -6.871 40.809 24.047 1.00 58.49 ? 347 VAL A O 1 ATOM 2768 C CB . VAL A 1 343 ? -9.583 40.055 22.745 1.00 58.38 ? 347 VAL A CB 1 ATOM 2769 C CG1 . VAL A 1 343 ? -10.091 40.953 23.876 1.00 58.78 ? 347 VAL A CG1 1 ATOM 2770 C CG2 . VAL A 1 343 ? -9.205 40.872 21.517 1.00 58.44 ? 347 VAL A CG2 1 ATOM 2771 N N . LYS A 1 344 ? -6.222 39.630 22.246 1.00 58.13 ? 348 LYS A N 1 ATOM 2772 C CA . LYS A 1 344 ? -4.994 40.387 22.059 1.00 58.01 ? 348 LYS A CA 1 ATOM 2773 C C . LYS A 1 344 ? -5.262 41.610 21.166 1.00 57.61 ? 348 LYS A C 1 ATOM 2774 O O . LYS A 1 344 ? -5.664 41.473 20.009 1.00 57.54 ? 348 LYS A O 1 ATOM 2775 C CB . LYS A 1 344 ? -3.887 39.493 21.496 1.00 58.05 ? 348 LYS A CB 1 ATOM 2776 C CG . LYS A 1 344 ? -2.550 40.198 21.304 1.00 59.75 ? 348 LYS A CG 1 ATOM 2777 C CD . LYS A 1 344 ? -2.005 40.752 22.623 1.00 62.01 ? 348 LYS A CD 1 ATOM 2778 C CE . LYS A 1 344 ? -0.741 41.578 22.421 1.00 62.23 ? 348 LYS A CE 1 ATOM 2779 N NZ . LYS A 1 344 ? -0.480 42.401 23.640 1.00 62.40 ? 348 LYS A NZ 1 ATOM 2780 N N . ASN A 1 345 ? -5.046 42.799 21.725 1.00 57.20 ? 349 ASN A N 1 ATOM 2781 C CA . ASN A 1 345 ? -5.408 44.054 21.065 1.00 56.76 ? 349 ASN A CA 1 ATOM 2782 C C . ASN A 1 345 ? -4.237 45.006 20.839 1.00 56.40 ? 349 ASN A C 1 ATOM 2783 O O . ASN A 1 345 ? -3.347 45.110 21.678 1.00 56.45 ? 349 ASN A O 1 ATOM 2784 C CB . ASN A 1 345 ? -6.503 44.775 21.854 1.00 56.75 ? 349 ASN A CB 1 ATOM 2785 C CG . ASN A 1 345 ? -6.912 46.087 21.212 1.00 57.14 ? 349 ASN A CG 1 ATOM 2786 O OD1 . ASN A 1 345 ? -6.880 47.139 21.846 1.00 58.07 ? 349 ASN A OD1 1 ATOM 2787 N ND2 . ASN A 1 345 ? -7.278 46.034 19.937 1.00 57.54 ? 349 ASN A ND2 1 ATOM 2788 N N . LEU A 1 346 ? -4.251 45.697 19.700 1.00 55.95 ? 350 LEU A N 1 ATOM 2789 C CA . LEU A 1 346 ? -3.246 46.705 19.391 1.00 55.74 ? 350 LEU A CA 1 ATOM 2790 C C . LEU A 1 346 ? -3.865 47.937 18.734 1.00 55.76 ? 350 LEU A C 1 ATOM 2791 O O . LEU A 1 346 ? -4.455 47.843 17.656 1.00 55.87 ? 350 LEU A O 1 ATOM 2792 C CB . LEU A 1 346 ? -2.153 46.122 18.500 1.00 55.68 ? 350 LEU A CB 1 ATOM 2793 C CG . LEU A 1 346 ? -1.184 45.125 19.135 1.00 55.30 ? 350 LEU A CG 1 ATOM 2794 C CD1 . LEU A 1 346 ? -0.273 44.532 18.070 1.00 54.32 ? 350 LEU A CD1 1 ATOM 2795 C CD2 . LEU A 1 346 ? -0.376 45.787 20.248 1.00 55.41 ? 350 LEU A CD2 1 ATOM 2796 N N . ARG A 1 347 ? -3.722 49.088 19.394 1.00 55.59 ? 351 ARG A N 1 ATOM 2797 C CA . ARG A 1 347 ? -4.293 50.347 18.909 1.00 55.37 ? 351 ARG A CA 1 ATOM 2798 C C . ARG A 1 347 ? -3.241 51.309 18.401 1.00 55.12 ? 351 ARG A C 1 ATOM 2799 O O . ARG A 1 347 ? -2.071 51.222 18.776 1.00 55.13 ? 351 ARG A O 1 ATOM 2800 C CB . ARG A 1 347 ? -5.099 51.049 19.998 1.00 55.35 ? 351 ARG A CB 1 ATOM 2801 C CG . ARG A 1 347 ? -6.325 50.295 20.408 1.00 56.11 ? 351 ARG A CG 1 ATOM 2802 C CD . ARG A 1 347 ? -7.393 51.208 20.950 1.00 56.57 ? 351 ARG A CD 1 ATOM 2803 N NE . ARG A 1 347 ? -8.612 50.443 21.191 1.00 58.05 ? 351 ARG A NE 1 ATOM 2804 C CZ . ARG A 1 347 ? -9.541 50.185 20.268 1.00 58.70 ? 351 ARG A CZ 1 ATOM 2805 N NH1 . ARG A 1 347 ? -9.412 50.634 19.019 1.00 58.34 ? 351 ARG A NH1 1 ATOM 2806 N NH2 . ARG A 1 347 ? -10.614 49.479 20.601 1.00 58.86 ? 351 ARG A NH2 1 ATOM 2807 N N . ASN A 1 348 ? -3.679 52.215 17.532 1.00 54.71 ? 352 ASN A N 1 ATOM 2808 C CA . ASN A 1 348 ? -2.883 53.352 17.089 1.00 54.46 ? 352 ASN A CA 1 ATOM 2809 C C . ASN A 1 348 ? -1.391 53.078 17.020 1.00 54.16 ? 352 ASN A C 1 ATOM 2810 O O . ASN A 1 348 ? -0.603 53.781 17.637 1.00 54.31 ? 352 ASN A O 1 ATOM 2811 C CB . ASN A 1 348 ? -3.165 54.557 17.988 1.00 54.42 ? 352 ASN A CB 1 ATOM 2812 C CG . ASN A 1 348 ? -4.647 54.799 18.171 1.00 54.72 ? 352 ASN A CG 1 ATOM 2813 O OD1 . ASN A 1 348 ? -5.206 54.477 19.220 1.00 55.16 ? 352 ASN A OD1 1 ATOM 2814 N ND2 . ASN A 1 348 ? -5.304 55.331 17.135 1.00 54.22 ? 352 ASN A ND2 1 ATOM 2815 N N . LYS A 1 349 ? -1.014 52.042 16.285 1.00 53.89 ? 353 LYS A N 1 ATOM 2816 C CA . LYS A 1 349 ? 0.389 51.760 16.031 1.00 53.99 ? 353 LYS A CA 1 ATOM 2817 C C . LYS A 1 349 ? 0.730 52.250 14.629 1.00 54.04 ? 353 LYS A C 1 ATOM 2818 O O . LYS A 1 349 ? -0.144 52.386 13.768 1.00 53.99 ? 353 LYS A O 1 ATOM 2819 C CB . LYS A 1 349 ? 0.701 50.265 16.179 1.00 54.03 ? 353 LYS A CB 1 ATOM 2820 C CG . LYS A 1 349 ? 0.346 49.653 17.541 1.00 54.31 ? 353 LYS A CG 1 ATOM 2821 C CD . LYS A 1 349 ? 1.463 49.818 18.567 1.00 54.71 ? 353 LYS A CD 1 ATOM 2822 C CE . LYS A 1 349 ? 1.055 49.302 19.955 1.00 54.34 ? 353 LYS A CE 1 ATOM 2823 N NZ . LYS A 1 349 ? 0.475 50.378 20.811 1.00 53.27 ? 353 LYS A NZ 1 ATOM 2824 N N . VAL A 1 350 ? 2.006 52.533 14.412 1.00 54.13 ? 354 VAL A N 1 ATOM 2825 C CA . VAL A 1 350 ? 2.464 53.072 13.146 1.00 54.16 ? 354 VAL A CA 1 ATOM 2826 C C . VAL A 1 350 ? 3.407 52.058 12.511 1.00 54.33 ? 354 VAL A C 1 ATOM 2827 O O . VAL A 1 350 ? 4.453 51.722 13.082 1.00 54.43 ? 354 VAL A O 1 ATOM 2828 C CB . VAL A 1 350 ? 3.182 54.445 13.326 1.00 54.10 ? 354 VAL A CB 1 ATOM 2829 C CG1 . VAL A 1 350 ? 3.303 55.166 11.986 1.00 54.03 ? 354 VAL A CG1 1 ATOM 2830 C CG2 . VAL A 1 350 ? 2.450 55.327 14.342 1.00 53.59 ? 354 VAL A CG2 1 ATOM 2831 N N . LEU A 1 351 ? 3.016 51.550 11.347 1.00 54.32 ? 355 LEU A N 1 ATOM 2832 C CA . LEU A 1 351 ? 3.875 50.672 10.572 1.00 54.46 ? 355 LEU A CA 1 ATOM 2833 C C . LEU A 1 351 ? 4.628 51.511 9.558 1.00 54.70 ? 355 LEU A C 1 ATOM 2834 O O . LEU A 1 351 ? 4.089 51.826 8.491 1.00 54.96 ? 355 LEU A O 1 ATOM 2835 C CB . LEU A 1 351 ? 3.056 49.604 9.841 1.00 54.48 ? 355 LEU A CB 1 ATOM 2836 C CG . LEU A 1 351 ? 2.127 48.649 10.590 1.00 54.05 ? 355 LEU A CG 1 ATOM 2837 C CD1 . LEU A 1 351 ? 1.519 47.691 9.590 1.00 54.00 ? 355 LEU A CD1 1 ATOM 2838 C CD2 . LEU A 1 351 ? 2.862 47.879 11.676 1.00 54.01 ? 355 LEU A CD2 1 ATOM 2839 N N . LYS A 1 352 ? 5.860 51.892 9.891 1.00 54.75 ? 356 LYS A N 1 ATOM 2840 C CA . LYS A 1 352 ? 6.688 52.688 8.976 1.00 54.76 ? 356 LYS A CA 1 ATOM 2841 C C . LYS A 1 352 ? 7.094 51.868 7.752 1.00 54.53 ? 356 LYS A C 1 ATOM 2842 O O . LYS A 1 352 ? 6.961 50.641 7.747 1.00 54.54 ? 356 LYS A O 1 ATOM 2843 C CB . LYS A 1 352 ? 7.919 53.266 9.689 1.00 54.77 ? 356 LYS A CB 1 ATOM 2844 C CG . LYS A 1 352 ? 7.616 54.522 10.496 1.00 55.49 ? 356 LYS A CG 1 ATOM 2845 C CD . LYS A 1 352 ? 8.874 55.335 10.800 1.00 57.15 ? 356 LYS A CD 1 ATOM 2846 C CE . LYS A 1 352 ? 9.725 54.705 11.916 1.00 58.07 ? 356 LYS A CE 1 ATOM 2847 N NZ . LYS A 1 352 ? 10.938 55.523 12.253 1.00 57.84 ? 356 LYS A NZ 1 ATOM 2848 N N . SER A 1 353 ? 7.569 52.544 6.708 1.00 54.24 ? 357 SER A N 1 ATOM 2849 C CA . SER A 1 353 ? 8.055 51.844 5.528 1.00 53.79 ? 357 SER A CA 1 ATOM 2850 C C . SER A 1 353 ? 8.999 50.713 5.937 1.00 53.77 ? 357 SER A C 1 ATOM 2851 O O . SER A 1 353 ? 9.899 50.908 6.756 1.00 53.52 ? 357 SER A O 1 ATOM 2852 C CB . SER A 1 353 ? 8.760 52.801 4.573 1.00 53.63 ? 357 SER A CB 1 ATOM 2853 O OG . SER A 1 353 ? 9.369 52.081 3.514 1.00 53.10 ? 357 SER A OG 1 ATOM 2854 N N . GLY A 1 354 ? 8.754 49.528 5.384 1.00 53.82 ? 358 GLY A N 1 ATOM 2855 C CA . GLY A 1 354 ? 9.607 48.360 5.589 1.00 53.58 ? 358 GLY A CA 1 ATOM 2856 C C . GLY A 1 354 ? 9.532 47.726 6.969 1.00 53.50 ? 358 GLY A C 1 ATOM 2857 O O . GLY A 1 354 ? 10.406 46.945 7.329 1.00 53.78 ? 358 GLY A O 1 ATOM 2858 N N . SER A 1 355 ? 8.495 48.037 7.741 1.00 53.21 ? 359 SER A N 1 ATOM 2859 C CA . SER A 1 355 ? 8.389 47.497 9.093 1.00 53.08 ? 359 SER A CA 1 ATOM 2860 C C . SER A 1 355 ? 7.406 46.327 9.238 1.00 52.87 ? 359 SER A C 1 ATOM 2861 O O . SER A 1 355 ? 6.587 46.067 8.352 1.00 52.63 ? 359 SER A O 1 ATOM 2862 C CB . SER A 1 355 ? 8.073 48.615 10.097 1.00 53.22 ? 359 SER A CB 1 ATOM 2863 O OG . SER A 1 355 ? 6.813 49.207 9.835 1.00 53.80 ? 359 SER A OG 1 ATOM 2864 N N . ARG A 1 356 ? 7.541 45.612 10.358 1.00 52.74 ? 360 ARG A N 1 ATOM 2865 C CA . ARG A 1 356 ? 6.649 44.521 10.769 1.00 52.62 ? 360 ARG A CA 1 ATOM 2866 C C . ARG A 1 356 ? 6.369 44.632 12.256 1.00 52.26 ? 360 ARG A C 1 ATOM 2867 O O . ARG A 1 356 ? 7.201 45.123 13.018 1.00 52.33 ? 360 ARG A O 1 ATOM 2868 C CB . ARG A 1 356 ? 7.282 43.158 10.515 1.00 52.71 ? 360 ARG A CB 1 ATOM 2869 C CG . ARG A 1 356 ? 7.613 42.872 9.067 1.00 54.04 ? 360 ARG A CG 1 ATOM 2870 C CD . ARG A 1 356 ? 8.133 41.465 8.900 1.00 55.44 ? 360 ARG A CD 1 ATOM 2871 N NE . ARG A 1 356 ? 9.124 41.107 9.914 1.00 57.26 ? 360 ARG A NE 1 ATOM 2872 C CZ . ARG A 1 356 ? 10.422 41.397 9.842 1.00 57.61 ? 360 ARG A CZ 1 ATOM 2873 N NH1 . ARG A 1 356 ? 10.911 42.069 8.801 1.00 56.94 ? 360 ARG A NH1 1 ATOM 2874 N NH2 . ARG A 1 356 ? 11.231 41.011 10.823 1.00 57.64 ? 360 ARG A NH2 1 ATOM 2875 N N . LEU A 1 357 ? 5.208 44.153 12.674 1.00 51.86 ? 361 LEU A N 1 ATOM 2876 C CA . LEU A 1 357 ? 4.816 44.235 14.069 1.00 51.62 ? 361 LEU A CA 1 ATOM 2877 C C . LEU A 1 357 ? 4.197 42.899 14.490 1.00 51.38 ? 361 LEU A C 1 ATOM 2878 O O . LEU A 1 357 ? 3.063 42.594 14.090 1.00 51.31 ? 361 LEU A O 1 ATOM 2879 C CB . LEU A 1 357 ? 3.872 45.436 14.265 1.00 51.54 ? 361 LEU A CB 1 ATOM 2880 C CG . LEU A 1 357 ? 2.765 45.533 15.325 1.00 52.16 ? 361 LEU A CG 1 ATOM 2881 C CD1 . LEU A 1 357 ? 3.272 45.356 16.763 1.00 53.23 ? 361 LEU A CD1 1 ATOM 2882 C CD2 . LEU A 1 357 ? 2.047 46.858 15.179 1.00 51.74 ? 361 LEU A CD2 1 ATOM 2883 N N . GLU A 1 358 ? 4.957 42.100 15.261 1.00 50.89 ? 362 GLU A N 1 ATOM 2884 C CA . GLU A 1 358 ? 4.486 40.773 15.702 1.00 50.61 ? 362 GLU A CA 1 ATOM 2885 C C . GLU A 1 358 ? 3.308 40.908 16.657 1.00 50.30 ? 362 GLU A C 1 ATOM 2886 O O . GLU A 1 358 ? 3.340 41.732 17.574 1.00 50.29 ? 362 GLU A O 1 ATOM 2887 C CB . GLU A 1 358 ? 5.594 39.880 16.321 1.00 50.29 ? 362 GLU A CB 1 ATOM 2888 C CG . GLU A 1 358 ? 5.029 38.511 16.841 1.00 50.76 ? 362 GLU A CG 1 ATOM 2889 C CD . GLU A 1 358 ? 6.037 37.338 16.990 1.00 50.66 ? 362 GLU A CD 1 ATOM 2890 O OE1 . GLU A 1 358 ? 7.250 37.522 16.730 1.00 49.85 ? 362 GLU A OE1 1 ATOM 2891 O OE2 . GLU A 1 358 ? 5.590 36.220 17.375 1.00 48.44 ? 362 GLU A OE2 1 ATOM 2892 N N . VAL A 1 359 ? 2.257 40.131 16.401 1.00 49.93 ? 363 VAL A N 1 ATOM 2893 C CA . VAL A 1 359 ? 1.190 39.950 17.375 1.00 49.95 ? 363 VAL A CA 1 ATOM 2894 C C . VAL A 1 359 ? 1.605 38.788 18.295 1.00 50.10 ? 363 VAL A C 1 ATOM 2895 O O . VAL A 1 359 ? 1.905 37.686 17.815 1.00 50.35 ? 363 VAL A O 1 ATOM 2896 C CB . VAL A 1 359 ? -0.171 39.653 16.710 1.00 49.80 ? 363 VAL A CB 1 ATOM 2897 C CG1 . VAL A 1 359 ? -1.247 39.538 17.760 1.00 49.78 ? 363 VAL A CG1 1 ATOM 2898 C CG2 . VAL A 1 359 ? -0.540 40.737 15.713 1.00 49.54 ? 363 VAL A CG2 1 ATOM 2899 N N . TYR A 1 360 ? 1.650 39.051 19.605 1.00 49.91 ? 364 TYR A N 1 ATOM 2900 C CA . TYR A 1 360 ? 2.082 38.064 20.598 1.00 49.42 ? 364 TYR A CA 1 ATOM 2901 C C . TYR A 1 360 ? 0.891 37.551 21.386 1.00 49.16 ? 364 TYR A C 1 ATOM 2902 O O . TYR A 1 360 ? -0.146 38.212 21.449 1.00 49.15 ? 364 TYR A O 1 ATOM 2903 C CB . TYR A 1 360 ? 3.059 38.684 21.603 1.00 49.53 ? 364 TYR A CB 1 ATOM 2904 C CG . TYR A 1 360 ? 4.423 39.068 21.080 1.00 49.52 ? 364 TYR A CG 1 ATOM 2905 C CD1 . TYR A 1 360 ? 4.791 40.415 20.975 1.00 49.16 ? 364 TYR A CD1 1 ATOM 2906 C CD2 . TYR A 1 360 ? 5.365 38.089 20.724 1.00 49.69 ? 364 TYR A CD2 1 ATOM 2907 C CE1 . TYR A 1 360 ? 6.056 40.791 20.508 1.00 49.35 ? 364 TYR A CE1 1 ATOM 2908 C CE2 . TYR A 1 360 ? 6.643 38.450 20.256 1.00 50.10 ? 364 TYR A CE2 1 ATOM 2909 C CZ . TYR A 1 360 ? 6.977 39.808 20.148 1.00 50.08 ? 364 TYR A CZ 1 ATOM 2910 O OH . TYR A 1 360 ? 8.222 40.183 19.685 1.00 49.94 ? 364 TYR A OH 1 ATOM 2911 N N . GLY A 1 361 ? 1.062 36.381 22.000 1.00 48.70 ? 365 GLY A N 1 ATOM 2912 C CA . GLY A 1 361 ? 0.115 35.864 22.984 1.00 48.11 ? 365 GLY A CA 1 ATOM 2913 C C . GLY A 1 361 ? -1.186 35.384 22.384 1.00 47.82 ? 365 GLY A C 1 ATOM 2914 O O . GLY A 1 361 ? -2.257 35.621 22.941 1.00 48.07 ? 365 GLY A O 1 ATOM 2915 N N . VAL A 1 362 ? -1.086 34.706 21.244 1.00 47.38 ? 366 VAL A N 1 ATOM 2916 C CA . VAL A 1 362 ? -2.240 34.156 20.530 1.00 46.66 ? 366 VAL A CA 1 ATOM 2917 C C . VAL A 1 362 ? -1.759 32.887 19.837 1.00 46.09 ? 366 VAL A C 1 ATOM 2918 O O . VAL A 1 362 ? -0.644 32.861 19.310 1.00 46.33 ? 366 VAL A O 1 ATOM 2919 C CB . VAL A 1 362 ? -2.834 35.209 19.519 1.00 46.67 ? 366 VAL A CB 1 ATOM 2920 C CG1 . VAL A 1 362 ? -3.266 34.584 18.208 1.00 46.70 ? 366 VAL A CG1 1 ATOM 2921 C CG2 . VAL A 1 362 ? -3.992 35.972 20.149 1.00 46.60 ? 366 VAL A CG2 1 ATOM 2922 N N . THR A 1 363 ? -2.562 31.824 19.874 1.00 45.24 ? 367 THR A N 1 ATOM 2923 C CA . THR A 1 363 ? -2.229 30.609 19.129 1.00 44.16 ? 367 THR A CA 1 ATOM 2924 C C . THR A 1 363 ? -2.348 30.945 17.644 1.00 43.81 ? 367 THR A C 1 ATOM 2925 O O . THR A 1 363 ? -3.455 31.009 17.093 1.00 43.93 ? 367 THR A O 1 ATOM 2926 C CB . THR A 1 363 ? -3.110 29.378 19.520 1.00 44.15 ? 367 THR A CB 1 ATOM 2927 O OG1 . THR A 1 363 ? -4.484 29.613 19.177 1.00 44.32 ? 367 THR A OG1 1 ATOM 2928 C CG2 . THR A 1 363 ? -2.998 29.080 21.004 1.00 42.98 ? 367 THR A CG2 1 ATOM 2929 N N . ALA A 1 364 ? -1.192 31.176 17.022 1.00 43.00 ? 368 ALA A N 1 ATOM 2930 C CA . ALA A 1 364 ? -1.085 31.747 15.673 1.00 42.06 ? 368 ALA A CA 1 ATOM 2931 C C . ALA A 1 364 ? -1.504 30.850 14.495 1.00 41.47 ? 368 ALA A C 1 ATOM 2932 O O . ALA A 1 364 ? -1.788 31.355 13.403 1.00 41.62 ? 368 ALA A O 1 ATOM 2933 C CB . ALA A 1 364 ? 0.317 32.288 15.450 1.00 42.00 ? 368 ALA A CB 1 ATOM 2934 N N . ALA A 1 365 ? -1.543 29.538 14.701 1.00 40.65 ? 369 ALA A N 1 ATOM 2935 C CA . ALA A 1 365 ? -1.992 28.629 13.646 1.00 40.08 ? 369 ALA A CA 1 ATOM 2936 C C . ALA A 1 365 ? -3.495 28.355 13.726 1.00 39.89 ? 369 ALA A C 1 ATOM 2937 O O . ALA A 1 365 ? -4.062 27.686 12.857 1.00 39.72 ? 369 ALA A O 1 ATOM 2938 C CB . ALA A 1 365 ? -1.215 27.341 13.694 1.00 40.00 ? 369 ALA A CB 1 ATOM 2939 N N . GLN A 1 366 ? -4.134 28.870 14.776 1.00 39.47 ? 370 GLN A N 1 ATOM 2940 C CA . GLN A 1 366 ? -5.556 28.662 14.994 1.00 39.19 ? 370 GLN A CA 1 ATOM 2941 C C . GLN A 1 366 ? -6.172 29.918 15.623 1.00 39.30 ? 370 GLN A C 1 ATOM 2942 O O . GLN A 1 366 ? -6.430 29.969 16.830 1.00 39.20 ? 370 GLN A O 1 ATOM 2943 C CB . GLN A 1 366 ? -5.780 27.406 15.846 1.00 38.92 ? 370 GLN A CB 1 ATOM 2944 C CG . GLN A 1 366 ? -7.199 26.870 15.808 1.00 38.41 ? 370 GLN A CG 1 ATOM 2945 C CD . GLN A 1 366 ? -7.321 25.479 16.392 1.00 37.79 ? 370 GLN A CD 1 ATOM 2946 O OE1 . GLN A 1 366 ? -6.596 24.559 16.000 1.00 37.11 ? 370 GLN A OE1 1 ATOM 2947 N NE2 . GLN A 1 366 ? -8.260 25.310 17.327 1.00 36.81 ? 370 GLN A NE2 1 ATOM 2948 N N . ALA A 1 367 ? -6.394 30.934 14.788 1.00 39.53 ? 371 ALA A N 1 ATOM 2949 C CA . ALA A 1 367 ? -6.780 32.263 15.269 1.00 39.99 ? 371 ALA A CA 1 ATOM 2950 C C . ALA A 1 367 ? -7.737 32.987 14.343 1.00 40.40 ? 371 ALA A C 1 ATOM 2951 O O . ALA A 1 367 ? -7.858 32.658 13.170 1.00 40.37 ? 371 ALA A O 1 ATOM 2952 C CB . ALA A 1 367 ? -5.548 33.123 15.507 1.00 39.84 ? 371 ALA A CB 1 ATOM 2953 N N . ASP A 1 368 ? -8.418 33.979 14.899 1.00 41.18 ? 372 ASP A N 1 ATOM 2954 C CA . ASP A 1 368 ? -9.262 34.874 14.136 1.00 41.93 ? 372 ASP A CA 1 ATOM 2955 C C . ASP A 1 368 ? -8.689 36.254 14.360 1.00 42.34 ? 372 ASP A C 1 ATOM 2956 O O . ASP A 1 368 ? -8.473 36.640 15.499 1.00 42.77 ? 372 ASP A O 1 ATOM 2957 C CB . ASP A 1 368 ? -10.697 34.803 14.656 1.00 42.05 ? 372 ASP A CB 1 ATOM 2958 C CG . ASP A 1 368 ? -11.674 35.609 13.816 1.00 42.54 ? 372 ASP A CG 1 ATOM 2959 O OD1 . ASP A 1 368 ? -11.281 36.122 12.744 1.00 43.81 ? 372 ASP A OD1 1 ATOM 2960 O OD2 . ASP A 1 368 ? -12.847 35.728 14.235 1.00 41.99 ? 372 ASP A OD2 1 ATOM 2961 N N . VAL A 1 369 ? -8.412 36.987 13.287 1.00 42.94 ? 373 VAL A N 1 ATOM 2962 C CA . VAL A 1 369 ? -7.757 38.299 13.414 1.00 43.49 ? 373 VAL A CA 1 ATOM 2963 C C . VAL A 1 369 ? -8.371 39.365 12.490 1.00 44.08 ? 373 VAL A C 1 ATOM 2964 O O . VAL A 1 369 ? -8.716 39.070 11.340 1.00 44.27 ? 373 VAL A O 1 ATOM 2965 C CB . VAL A 1 369 ? -6.185 38.198 13.297 1.00 43.31 ? 373 VAL A CB 1 ATOM 2966 C CG1 . VAL A 1 369 ? -5.768 37.029 12.451 1.00 43.06 ? 373 VAL A CG1 1 ATOM 2967 C CG2 . VAL A 1 369 ? -5.559 39.488 12.779 1.00 43.18 ? 373 VAL A CG2 1 ATOM 2968 N N . GLU A 1 370 ? -8.516 40.588 13.021 1.00 44.40 ? 374 GLU A N 1 ATOM 2969 C CA . GLU A 1 370 ? -9.138 41.722 12.320 1.00 44.44 ? 374 GLU A CA 1 ATOM 2970 C C . GLU A 1 370 ? -8.312 42.987 12.459 1.00 44.14 ? 374 GLU A C 1 ATOM 2971 O O . GLU A 1 370 ? -8.009 43.405 13.567 1.00 44.36 ? 374 GLU A O 1 ATOM 2972 C CB . GLU A 1 370 ? -10.501 42.019 12.917 1.00 44.70 ? 374 GLU A CB 1 ATOM 2973 C CG . GLU A 1 370 ? -11.600 41.044 12.576 1.00 46.37 ? 374 GLU A CG 1 ATOM 2974 C CD . GLU A 1 370 ? -12.896 41.398 13.289 1.00 48.62 ? 374 GLU A CD 1 ATOM 2975 O OE1 . GLU A 1 370 ? -12.856 42.253 14.213 1.00 48.32 ? 374 GLU A OE1 1 ATOM 2976 O OE2 . GLU A 1 370 ? -13.949 40.818 12.929 1.00 49.82 ? 374 GLU A OE2 1 ATOM 2977 N N . VAL A 1 371 ? -7.971 43.612 11.342 1.00 43.89 ? 375 VAL A N 1 ATOM 2978 C CA . VAL A 1 371 ? -7.166 44.823 11.365 1.00 43.87 ? 375 VAL A CA 1 ATOM 2979 C C . VAL A 1 371 ? -7.963 45.978 10.774 1.00 44.21 ? 375 VAL A C 1 ATOM 2980 O O . VAL A 1 371 ? -8.758 45.778 9.857 1.00 44.77 ? 375 VAL A O 1 ATOM 2981 C CB . VAL A 1 371 ? -5.892 44.675 10.509 1.00 43.85 ? 375 VAL A CB 1 ATOM 2982 C CG1 . VAL A 1 371 ? -4.742 45.450 11.127 1.00 43.47 ? 375 VAL A CG1 1 ATOM 2983 C CG2 . VAL A 1 371 ? -5.518 43.222 10.333 1.00 44.03 ? 375 VAL A CG2 1 ATOM 2984 N N . LEU A 1 372 ? -7.755 47.184 11.287 1.00 44.11 ? 376 LEU A N 1 ATOM 2985 C CA . LEU A 1 372 ? -8.234 48.372 10.604 1.00 44.27 ? 376 LEU A CA 1 ATOM 2986 C C . LEU A 1 372 ? -7.042 49.237 10.234 1.00 44.60 ? 376 LEU A C 1 ATOM 2987 O O . LEU A 1 372 ? -6.426 49.865 11.088 1.00 44.70 ? 376 LEU A O 1 ATOM 2988 C CB . LEU A 1 372 ? -9.223 49.148 11.470 1.00 44.27 ? 376 LEU A CB 1 ATOM 2989 C CG . LEU A 1 372 ? -10.703 48.771 11.364 1.00 44.48 ? 376 LEU A CG 1 ATOM 2990 C CD1 . LEU A 1 372 ? -11.461 49.366 12.525 1.00 44.26 ? 376 LEU A CD1 1 ATOM 2991 C CD2 . LEU A 1 372 ? -11.332 49.205 10.031 1.00 43.87 ? 376 LEU A CD2 1 ATOM 2992 N N . PHE A 1 373 ? -6.690 49.233 8.957 1.00 44.95 ? 377 PHE A N 1 ATOM 2993 C CA . PHE A 1 373 ? -5.640 50.107 8.471 1.00 45.12 ? 377 PHE A CA 1 ATOM 2994 C C . PHE A 1 373 ? -6.231 51.463 8.115 1.00 45.72 ? 377 PHE A C 1 ATOM 2995 O O . PHE A 1 373 ? -7.416 51.578 7.785 1.00 45.71 ? 377 PHE A O 1 ATOM 2996 C CB . PHE A 1 373 ? -4.977 49.520 7.233 1.00 44.86 ? 377 PHE A CB 1 ATOM 2997 C CG . PHE A 1 373 ? -4.346 48.180 7.451 1.00 44.45 ? 377 PHE A CG 1 ATOM 2998 C CD1 . PHE A 1 373 ? -3.076 48.076 8.008 1.00 44.03 ? 377 PHE A CD1 1 ATOM 2999 C CD2 . PHE A 1 373 ? -5.003 47.020 7.063 1.00 44.28 ? 377 PHE A CD2 1 ATOM 3000 C CE1 . PHE A 1 373 ? -2.481 46.840 8.200 1.00 43.52 ? 377 PHE A CE1 1 ATOM 3001 C CE2 . PHE A 1 373 ? -4.413 45.781 7.246 1.00 44.16 ? 377 PHE A CE2 1 ATOM 3002 C CZ . PHE A 1 373 ? -3.148 45.693 7.816 1.00 44.30 ? 377 PHE A CZ 1 ATOM 3003 N N . LYS A 1 374 ? -5.398 52.491 8.189 1.00 46.27 ? 378 LYS A N 1 ATOM 3004 C CA . LYS A 1 374 ? -5.774 53.806 7.713 1.00 46.86 ? 378 LYS A CA 1 ATOM 3005 C C . LYS A 1 374 ? -4.597 54.380 6.954 1.00 46.78 ? 378 LYS A C 1 ATOM 3006 O O . LYS A 1 374 ? -3.473 54.376 7.451 1.00 46.55 ? 378 LYS A O 1 ATOM 3007 C CB . LYS A 1 374 ? -6.149 54.706 8.879 1.00 47.24 ? 378 LYS A CB 1 ATOM 3008 C CG . LYS A 1 374 ? -6.725 56.048 8.463 1.00 49.09 ? 378 LYS A CG 1 ATOM 3009 C CD . LYS A 1 374 ? -6.615 57.077 9.593 1.00 52.56 ? 378 LYS A CD 1 ATOM 3010 C CE . LYS A 1 374 ? -7.754 56.960 10.632 1.00 54.12 ? 378 LYS A CE 1 ATOM 3011 N NZ . LYS A 1 374 ? -7.976 58.256 11.383 1.00 54.84 ? 378 LYS A NZ 1 ATOM 3012 N N . VAL A 1 375 ? -4.856 54.842 5.736 1.00 47.01 ? 379 VAL A N 1 ATOM 3013 C CA . VAL A 1 375 ? -3.828 55.500 4.938 1.00 47.30 ? 379 VAL A CA 1 ATOM 3014 C C . VAL A 1 375 ? -3.821 56.990 5.244 1.00 47.37 ? 379 VAL A C 1 ATOM 3015 O O . VAL A 1 375 ? -4.867 57.579 5.530 1.00 47.27 ? 379 VAL A O 1 ATOM 3016 C CB . VAL A 1 375 ? -4.029 55.282 3.431 1.00 47.38 ? 379 VAL A CB 1 ATOM 3017 C CG1 . VAL A 1 375 ? -3.948 53.803 3.100 1.00 47.58 ? 379 VAL A CG1 1 ATOM 3018 C CG2 . VAL A 1 375 ? -5.356 55.870 2.972 1.00 47.86 ? 379 VAL A CG2 1 ATOM 3019 N N . ARG A 1 376 ? -2.637 57.589 5.183 1.00 47.50 ? 380 ARG A N 1 ATOM 3020 C CA . ARG A 1 376 ? -2.465 58.990 5.553 1.00 47.73 ? 380 ARG A CA 1 ATOM 3021 C C . ARG A 1 376 ? -2.842 59.967 4.436 1.00 47.56 ? 380 ARG A C 1 ATOM 3022 O O . ARG A 1 376 ? -3.565 60.934 4.680 1.00 47.13 ? 380 ARG A O 1 ATOM 3023 C CB . ARG A 1 376 ? -1.033 59.247 6.051 1.00 47.62 ? 380 ARG A CB 1 ATOM 3024 C CG . ARG A 1 376 ? -0.730 58.594 7.400 1.00 48.44 ? 380 ARG A CG 1 ATOM 3025 C CD . ARG A 1 376 ? 0.638 58.978 7.971 1.00 48.59 ? 380 ARG A CD 1 ATOM 3026 N NE . ARG A 1 376 ? 0.688 58.691 9.407 1.00 51.02 ? 380 ARG A NE 1 ATOM 3027 C CZ . ARG A 1 376 ? 1.799 58.523 10.124 1.00 52.00 ? 380 ARG A CZ 1 ATOM 3028 N NH1 . ARG A 1 376 ? 2.998 58.601 9.553 1.00 51.74 ? 380 ARG A NH1 1 ATOM 3029 N NH2 . ARG A 1 376 ? 1.708 58.261 11.427 1.00 52.72 ? 380 ARG A NH2 1 ATOM 3030 N N . ASP A 1 377 ? -2.361 59.709 3.219 1.00 47.62 ? 381 ASP A N 1 ATOM 3031 C CA . ASP A 1 377 ? -2.438 60.689 2.136 1.00 47.92 ? 381 ASP A CA 1 ATOM 3032 C C . ASP A 1 377 ? -2.589 59.997 0.795 1.00 47.94 ? 381 ASP A C 1 ATOM 3033 O O . ASP A 1 377 ? -1.617 59.521 0.215 1.00 47.91 ? 381 ASP A O 1 ATOM 3034 C CB . ASP A 1 377 ? -1.191 61.594 2.146 1.00 48.19 ? 381 ASP A CB 1 ATOM 3035 C CG . ASP A 1 377 ? -1.191 62.638 1.023 1.00 48.93 ? 381 ASP A CG 1 ATOM 3036 O OD1 . ASP A 1 377 ? -2.268 62.967 0.484 1.00 49.62 ? 381 ASP A OD1 1 ATOM 3037 O OD2 . ASP A 1 377 ? -0.096 63.142 0.682 1.00 49.87 ? 381 ASP A OD2 1 ATOM 3038 N N . LEU A 1 378 ? -3.820 59.980 0.298 1.00 48.19 ? 382 LEU A N 1 ATOM 3039 C CA . LEU A 1 378 ? -4.180 59.223 -0.895 1.00 48.55 ? 382 LEU A CA 1 ATOM 3040 C C . LEU A 1 378 ? -3.480 59.670 -2.175 1.00 48.81 ? 382 LEU A C 1 ATOM 3041 O O . LEU A 1 378 ? -3.355 58.893 -3.124 1.00 48.83 ? 382 LEU A O 1 ATOM 3042 C CB . LEU A 1 378 ? -5.700 59.223 -1.078 1.00 48.45 ? 382 LEU A CB 1 ATOM 3043 C CG . LEU A 1 378 ? -6.441 58.315 -0.098 1.00 48.52 ? 382 LEU A CG 1 ATOM 3044 C CD1 . LEU A 1 378 ? -7.896 58.723 0.022 1.00 48.87 ? 382 LEU A CD1 1 ATOM 3045 C CD2 . LEU A 1 378 ? -6.310 56.852 -0.512 1.00 48.12 ? 382 LEU A CD2 1 ATOM 3046 N N . GLU A 1 379 ? -3.013 60.913 -2.188 1.00 49.25 ? 383 GLU A N 1 ATOM 3047 C CA . GLU A 1 379 ? -2.335 61.469 -3.351 1.00 49.92 ? 383 GLU A CA 1 ATOM 3048 C C . GLU A 1 379 ? -0.951 60.856 -3.570 1.00 49.71 ? 383 GLU A C 1 ATOM 3049 O O . GLU A 1 379 ? -0.327 61.086 -4.603 1.00 49.98 ? 383 GLU A O 1 ATOM 3050 C CB . GLU A 1 379 ? -2.230 62.988 -3.232 1.00 50.35 ? 383 GLU A CB 1 ATOM 3051 C CG . GLU A 1 379 ? -2.361 63.708 -4.570 1.00 52.92 ? 383 GLU A CG 1 ATOM 3052 C CD . GLU A 1 379 ? -1.920 65.168 -4.511 1.00 56.08 ? 383 GLU A CD 1 ATOM 3053 O OE1 . GLU A 1 379 ? -0.728 65.422 -4.191 1.00 56.31 ? 383 GLU A OE1 1 ATOM 3054 O OE2 . GLU A 1 379 ? -2.765 66.054 -4.808 1.00 57.10 ? 383 GLU A OE2 1 ATOM 3055 N N . LYS A 1 380 ? -0.477 60.077 -2.599 1.00 49.47 ? 384 LYS A N 1 ATOM 3056 C CA . LYS A 1 380 ? 0.791 59.359 -2.728 1.00 49.03 ? 384 LYS A CA 1 ATOM 3057 C C . LYS A 1 380 ? 0.634 58.012 -3.451 1.00 48.66 ? 384 LYS A C 1 ATOM 3058 O O . LYS A 1 380 ? 1.626 57.318 -3.690 1.00 48.67 ? 384 LYS A O 1 ATOM 3059 C CB . LYS A 1 380 ? 1.464 59.163 -1.356 1.00 49.15 ? 384 LYS A CB 1 ATOM 3060 C CG . LYS A 1 380 ? 1.850 60.457 -0.628 1.00 49.88 ? 384 LYS A CG 1 ATOM 3061 C CD . LYS A 1 380 ? 2.496 61.464 -1.577 1.00 51.34 ? 384 LYS A CD 1 ATOM 3062 C CE . LYS A 1 380 ? 2.493 62.874 -1.008 1.00 51.67 ? 384 LYS A CE 1 ATOM 3063 N NZ . LYS A 1 380 ? 3.685 63.097 -0.152 1.00 52.79 ? 384 LYS A NZ 1 ATOM 3064 N N . ALA A 1 381 ? -0.604 57.657 -3.803 1.00 47.99 ? 385 ALA A N 1 ATOM 3065 C CA . ALA A 1 381 ? -0.901 56.405 -4.508 1.00 47.49 ? 385 ALA A CA 1 ATOM 3066 C C . ALA A 1 381 ? -0.414 56.420 -5.960 1.00 47.18 ? 385 ALA A C 1 ATOM 3067 O O . ALA A 1 381 ? -0.640 57.392 -6.677 1.00 47.22 ? 385 ALA A O 1 ATOM 3068 C CB . ALA A 1 381 ? -2.394 56.135 -4.467 1.00 47.33 ? 385 ALA A CB 1 ATOM 3069 N N . ASP A 1 382 ? 0.246 55.350 -6.397 1.00 46.81 ? 386 ASP A N 1 ATOM 3070 C CA . ASP A 1 382 ? 0.613 55.223 -7.807 1.00 46.69 ? 386 ASP A CA 1 ATOM 3071 C C . ASP A 1 382 ? -0.646 55.106 -8.659 1.00 46.36 ? 386 ASP A C 1 ATOM 3072 O O . ASP A 1 382 ? -1.616 54.467 -8.252 1.00 46.27 ? 386 ASP A O 1 ATOM 3073 C CB . ASP A 1 382 ? 1.476 53.983 -8.082 1.00 46.98 ? 386 ASP A CB 1 ATOM 3074 C CG . ASP A 1 382 ? 2.398 53.620 -6.932 1.00 47.94 ? 386 ASP A CG 1 ATOM 3075 O OD1 . ASP A 1 382 ? 3.302 54.422 -6.585 1.00 48.64 ? 386 ASP A OD1 1 ATOM 3076 O OD2 . ASP A 1 382 ? 2.227 52.500 -6.396 1.00 48.78 ? 386 ASP A OD2 1 ATOM 3077 N N . VAL A 1 383 ? -0.621 55.722 -9.839 1.00 45.93 ? 387 VAL A N 1 ATOM 3078 C CA . VAL A 1 383 ? -1.689 55.563 -10.820 1.00 45.60 ? 387 VAL A CA 1 ATOM 3079 C C . VAL A 1 383 ? -1.535 54.171 -11.439 1.00 45.70 ? 387 VAL A C 1 ATOM 3080 O O . VAL A 1 383 ? -0.427 53.784 -11.825 1.00 45.79 ? 387 VAL A O 1 ATOM 3081 C CB . VAL A 1 383 ? -1.627 56.665 -11.920 1.00 45.52 ? 387 VAL A CB 1 ATOM 3082 C CG1 . VAL A 1 383 ? -2.739 56.489 -12.959 1.00 44.62 ? 387 VAL A CG1 1 ATOM 3083 C CG2 . VAL A 1 383 ? -1.690 58.060 -11.296 1.00 45.52 ? 387 VAL A CG2 1 ATOM 3084 N N . ILE A 1 384 ? -2.634 53.420 -11.510 1.00 45.57 ? 388 ILE A N 1 ATOM 3085 C CA . ILE A 1 384 ? -2.622 52.076 -12.092 1.00 45.68 ? 388 ILE A CA 1 ATOM 3086 C C . ILE A 1 384 ? -2.192 52.073 -13.569 1.00 45.97 ? 388 ILE A C 1 ATOM 3087 O O . ILE A 1 384 ? -2.624 52.928 -14.342 1.00 45.78 ? 388 ILE A O 1 ATOM 3088 C CB . ILE A 1 384 ? -3.988 51.350 -11.897 1.00 45.45 ? 388 ILE A CB 1 ATOM 3089 C CG1 . ILE A 1 384 ? -3.799 49.838 -12.023 1.00 45.70 ? 388 ILE A CG1 1 ATOM 3090 C CG2 . ILE A 1 384 ? -5.051 51.870 -12.868 1.00 44.60 ? 388 ILE A CG2 1 ATOM 3091 C CD1 . ILE A 1 384 ? -4.837 49.013 -11.300 1.00 46.04 ? 388 ILE A CD1 1 ATOM 3092 N N . GLU A 1 385 ? -1.322 51.130 -13.941 1.00 46.49 ? 389 GLU A N 1 ATOM 3093 C CA . GLU A 1 385 ? -0.937 50.950 -15.337 1.00 47.34 ? 389 GLU A CA 1 ATOM 3094 C C . GLU A 1 385 ? -2.198 50.632 -16.126 1.00 48.21 ? 389 GLU A C 1 ATOM 3095 O O . GLU A 1 385 ? -3.043 49.855 -15.662 1.00 48.28 ? 389 GLU A O 1 ATOM 3096 C CB . GLU A 1 385 ? 0.066 49.804 -15.527 1.00 47.28 ? 389 GLU A CB 1 ATOM 3097 C CG . GLU A 1 385 ? 1.425 49.965 -14.839 1.00 47.64 ? 389 GLU A CG 1 ATOM 3098 C CD . GLU A 1 385 ? 2.278 51.098 -15.394 1.00 46.97 ? 389 GLU A CD 1 ATOM 3099 O OE1 . GLU A 1 385 ? 2.724 51.022 -16.559 1.00 46.08 ? 389 GLU A OE1 1 ATOM 3100 O OE2 . GLU A 1 385 ? 2.522 52.055 -14.636 1.00 46.77 ? 389 GLU A OE2 1 ATOM 3101 N N . PRO A 1 386 ? -2.328 51.220 -17.330 1.00 48.86 ? 390 PRO A N 1 ATOM 3102 C CA . PRO A 1 386 ? -3.555 51.097 -18.119 1.00 49.24 ? 390 PRO A CA 1 ATOM 3103 C C . PRO A 1 386 ? -3.927 49.640 -18.404 1.00 49.73 ? 390 PRO A C 1 ATOM 3104 O O . PRO A 1 386 ? -5.110 49.312 -18.498 1.00 50.03 ? 390 PRO A O 1 ATOM 3105 C CB . PRO A 1 386 ? -3.203 51.827 -19.425 1.00 49.29 ? 390 PRO A CB 1 ATOM 3106 C CG . PRO A 1 386 ? -1.697 51.841 -19.465 1.00 48.87 ? 390 PRO A CG 1 ATOM 3107 C CD . PRO A 1 386 ? -1.306 52.012 -18.037 1.00 48.76 ? 390 PRO A CD 1 ATOM 3108 N N . SER A 1 387 ? -2.920 48.780 -18.519 1.00 50.09 ? 391 SER A N 1 ATOM 3109 C CA . SER A 1 387 ? -3.127 47.396 -18.908 1.00 50.64 ? 391 SER A CA 1 ATOM 3110 C C . SER A 1 387 ? -3.516 46.481 -17.737 1.00 50.88 ? 391 SER A C 1 ATOM 3111 O O . SER A 1 387 ? -3.970 45.357 -17.964 1.00 51.11 ? 391 SER A O 1 ATOM 3112 C CB . SER A 1 387 ? -1.864 46.856 -19.588 1.00 50.81 ? 391 SER A CB 1 ATOM 3113 O OG . SER A 1 387 ? -0.884 46.489 -18.625 1.00 51.20 ? 391 SER A OG 1 ATOM 3114 N N . TRP A 1 388 ? -3.327 46.949 -16.500 1.00 50.90 ? 392 TRP A N 1 ATOM 3115 C CA . TRP A 1 388 ? -3.556 46.115 -15.303 1.00 50.75 ? 392 TRP A CA 1 ATOM 3116 C C . TRP A 1 388 ? -5.034 45.933 -14.932 1.00 49.92 ? 392 TRP A C 1 ATOM 3117 O O . TRP A 1 388 ? -5.588 46.702 -14.142 1.00 50.00 ? 392 TRP A O 1 ATOM 3118 C CB . TRP A 1 388 ? -2.758 46.636 -14.096 1.00 51.55 ? 392 TRP A CB 1 ATOM 3119 C CG . TRP A 1 388 ? -1.268 46.503 -14.242 1.00 52.66 ? 392 TRP A CG 1 ATOM 3120 C CD1 . TRP A 1 388 ? -0.589 45.916 -15.280 1.00 53.82 ? 392 TRP A CD1 1 ATOM 3121 C CD2 . TRP A 1 388 ? -0.269 46.935 -13.306 1.00 53.58 ? 392 TRP A CD2 1 ATOM 3122 N NE1 . TRP A 1 388 ? 0.770 45.977 -15.056 1.00 54.44 ? 392 TRP A NE1 1 ATOM 3123 C CE2 . TRP A 1 388 ? 0.996 46.591 -13.852 1.00 53.90 ? 392 TRP A CE2 1 ATOM 3124 C CE3 . TRP A 1 388 ? -0.316 47.588 -12.064 1.00 53.98 ? 392 TRP A CE3 1 ATOM 3125 C CZ2 . TRP A 1 388 ? 2.204 46.869 -13.197 1.00 53.51 ? 392 TRP A CZ2 1 ATOM 3126 C CZ3 . TRP A 1 388 ? 0.891 47.871 -11.409 1.00 53.93 ? 392 TRP A CZ3 1 ATOM 3127 C CH2 . TRP A 1 388 ? 2.134 47.510 -11.983 1.00 53.60 ? 392 TRP A CH2 1 ATOM 3128 N N . THR A 1 389 ? -5.650 44.890 -15.481 1.00 48.66 ? 393 THR A N 1 ATOM 3129 C CA . THR A 1 389 ? -7.074 44.651 -15.290 1.00 47.61 ? 393 THR A CA 1 ATOM 3130 C C . THR A 1 389 ? -7.396 43.330 -14.597 1.00 46.83 ? 393 THR A C 1 ATOM 3131 O O . THR A 1 389 ? -8.508 43.149 -14.091 1.00 46.52 ? 393 THR A O 1 ATOM 3132 C CB . THR A 1 389 ? -7.807 44.652 -16.628 1.00 47.89 ? 393 THR A CB 1 ATOM 3133 O OG1 . THR A 1 389 ? -7.133 43.767 -17.533 1.00 47.45 ? 393 THR A OG1 1 ATOM 3134 C CG2 . THR A 1 389 ? -7.858 46.057 -17.215 1.00 48.08 ? 393 THR A CG2 1 ATOM 3135 N N . ASP A 1 390 ? -6.439 42.403 -14.602 1.00 45.82 ? 394 ASP A N 1 ATOM 3136 C CA . ASP A 1 390 ? -6.596 41.120 -13.922 1.00 44.82 ? 394 ASP A CA 1 ATOM 3137 C C . ASP A 1 390 ? -5.925 41.181 -12.547 1.00 44.28 ? 394 ASP A C 1 ATOM 3138 O O . ASP A 1 390 ? -4.697 41.148 -12.458 1.00 44.40 ? 394 ASP A O 1 ATOM 3139 C CB . ASP A 1 390 ? -5.984 40.008 -14.776 1.00 44.76 ? 394 ASP A CB 1 ATOM 3140 C CG . ASP A 1 390 ? -6.317 38.601 -14.270 1.00 44.59 ? 394 ASP A CG 1 ATOM 3141 O OD1 . ASP A 1 390 ? -6.301 38.345 -13.044 1.00 43.47 ? 394 ASP A OD1 1 ATOM 3142 O OD2 . ASP A 1 390 ? -6.570 37.732 -15.129 1.00 44.80 ? 394 ASP A OD2 1 ATOM 3143 N N . PRO A 1 391 ? -6.723 41.263 -11.466 1.00 43.64 ? 395 PRO A N 1 ATOM 3144 C CA . PRO A 1 391 ? -6.132 41.403 -10.135 1.00 43.36 ? 395 PRO A CA 1 ATOM 3145 C C . PRO A 1 391 ? -5.184 40.269 -9.746 1.00 43.17 ? 395 PRO A C 1 ATOM 3146 O O . PRO A 1 391 ? -4.195 40.513 -9.054 1.00 43.17 ? 395 PRO A O 1 ATOM 3147 C CB . PRO A 1 391 ? -7.346 41.454 -9.195 1.00 43.31 ? 395 PRO A CB 1 ATOM 3148 C CG . PRO A 1 391 ? -8.485 40.973 -9.981 1.00 43.44 ? 395 PRO A CG 1 ATOM 3149 C CD . PRO A 1 391 ? -8.193 41.242 -11.418 1.00 43.57 ? 395 PRO A CD 1 ATOM 3150 N N . GLN A 1 392 ? -5.466 39.046 -10.189 1.00 43.02 ? 396 GLN A N 1 ATOM 3151 C CA . GLN A 1 392 ? -4.578 37.925 -9.882 1.00 42.84 ? 396 GLN A CA 1 ATOM 3152 C C . GLN A 1 392 ? -3.182 38.098 -10.498 1.00 43.36 ? 396 GLN A C 1 ATOM 3153 O O . GLN A 1 392 ? -2.176 37.838 -9.833 1.00 43.27 ? 396 GLN A O 1 ATOM 3154 C CB . GLN A 1 392 ? -5.189 36.590 -10.290 1.00 42.19 ? 396 GLN A CB 1 ATOM 3155 C CG . GLN A 1 392 ? -4.268 35.423 -10.009 1.00 40.75 ? 396 GLN A CG 1 ATOM 3156 C CD . GLN A 1 392 ? -4.919 34.086 -10.257 1.00 39.39 ? 396 GLN A CD 1 ATOM 3157 O OE1 . GLN A 1 392 ? -5.781 33.952 -11.123 1.00 38.55 ? 396 GLN A OE1 1 ATOM 3158 N NE2 . GLN A 1 392 ? -4.502 33.078 -9.500 1.00 38.24 ? 396 GLN A NE2 1 ATOM 3159 N N . LEU A 1 393 ? -3.129 38.545 -11.754 1.00 44.00 ? 397 LEU A N 1 ATOM 3160 C CA . LEU A 1 393 ? -1.852 38.767 -12.448 1.00 44.74 ? 397 LEU A CA 1 ATOM 3161 C C . LEU A 1 393 ? -1.029 39.897 -11.824 1.00 44.93 ? 397 LEU A C 1 ATOM 3162 O O . LEU A 1 393 ? 0.199 39.826 -11.801 1.00 45.07 ? 397 LEU A O 1 ATOM 3163 C CB . LEU A 1 393 ? -2.062 39.023 -13.947 1.00 44.86 ? 397 LEU A CB 1 ATOM 3164 C CG . LEU A 1 393 ? -2.493 37.831 -14.818 1.00 45.80 ? 397 LEU A CG 1 ATOM 3165 C CD1 . LEU A 1 393 ? -2.936 38.312 -16.205 1.00 46.40 ? 397 LEU A CD1 1 ATOM 3166 C CD2 . LEU A 1 393 ? -1.394 36.760 -14.940 1.00 46.15 ? 397 LEU A CD2 1 ATOM 3167 N N . ILE A 1 394 ? -1.707 40.929 -11.317 1.00 45.11 ? 398 ILE A N 1 ATOM 3168 C CA . ILE A 1 394 ? -1.035 42.035 -10.630 1.00 45.09 ? 398 ILE A CA 1 ATOM 3169 C C . ILE A 1 394 ? -0.300 41.533 -9.389 1.00 45.30 ? 398 ILE A C 1 ATOM 3170 O O . ILE A 1 394 ? 0.893 41.757 -9.246 1.00 45.54 ? 398 ILE A O 1 ATOM 3171 C CB . ILE A 1 394 ? -2.010 43.183 -10.252 1.00 45.08 ? 398 ILE A CB 1 ATOM 3172 C CG1 . ILE A 1 394 ? -2.817 43.637 -11.475 1.00 44.45 ? 398 ILE A CG1 1 ATOM 3173 C CG2 . ILE A 1 394 ? -1.244 44.357 -9.628 1.00 44.60 ? 398 ILE A CG2 1 ATOM 3174 C CD1 . ILE A 1 394 ? -4.042 44.451 -11.120 1.00 44.68 ? 398 ILE A CD1 1 ATOM 3175 N N . CYS A 1 395 ? -1.010 40.837 -8.509 1.00 45.74 ? 399 CYS A N 1 ATOM 3176 C CA . CYS A 1 395 ? -0.392 40.234 -7.327 1.00 46.25 ? 399 CYS A CA 1 ATOM 3177 C C . CYS A 1 395 ? 0.744 39.277 -7.689 1.00 47.16 ? 399 CYS A C 1 ATOM 3178 O O . CYS A 1 395 ? 1.761 39.248 -6.999 1.00 47.29 ? 399 CYS A O 1 ATOM 3179 C CB . CYS A 1 395 ? -1.438 39.501 -6.495 1.00 45.84 ? 399 CYS A CB 1 ATOM 3180 S SG . CYS A 1 395 ? -2.817 40.533 -6.029 1.00 44.33 ? 399 CYS A SG 1 ATOM 3181 N N . SER A 1 396 ? 0.559 38.506 -8.766 1.00 48.10 ? 400 SER A N 1 ATOM 3182 C CA . SER A 1 396 ? 1.577 37.585 -9.289 1.00 49.03 ? 400 SER A CA 1 ATOM 3183 C C . SER A 1 396 ? 2.900 38.250 -9.668 1.00 49.82 ? 400 SER A C 1 ATOM 3184 O O . SER A 1 396 ? 3.964 37.744 -9.321 1.00 49.69 ? 400 SER A O 1 ATOM 3185 C CB . SER A 1 396 ? 1.052 36.849 -10.515 1.00 48.81 ? 400 SER A CB 1 ATOM 3186 O OG . SER A 1 396 ? 0.088 35.901 -10.147 1.00 49.15 ? 400 SER A OG 1 ATOM 3187 N N . LYS A 1 397 ? 2.833 39.366 -10.390 1.00 50.96 ? 401 LYS A N 1 ATOM 3188 C CA . LYS A 1 397 ? 4.044 40.017 -10.866 1.00 52.33 ? 401 LYS A CA 1 ATOM 3189 C C . LYS A 1 397 ? 4.726 40.832 -9.763 1.00 52.74 ? 401 LYS A C 1 ATOM 3190 O O . LYS A 1 397 ? 5.955 40.820 -9.649 1.00 53.23 ? 401 LYS A O 1 ATOM 3191 C CB . LYS A 1 397 ? 3.780 40.875 -12.116 1.00 52.67 ? 401 LYS A CB 1 ATOM 3192 C CG . LYS A 1 397 ? 4.770 40.609 -13.296 1.00 54.68 ? 401 LYS A CG 1 ATOM 3193 C CD . LYS A 1 397 ? 6.289 40.692 -12.898 1.00 56.05 ? 401 LYS A CD 1 ATOM 3194 C CE . LYS A 1 397 ? 7.044 41.842 -13.589 1.00 56.78 ? 401 LYS A CE 1 ATOM 3195 N NZ . LYS A 1 397 ? 6.489 43.212 -13.324 1.00 56.51 ? 401 LYS A NZ 1 ATOM 3196 N N . MET A 1 398 ? 3.937 41.516 -8.941 1.00 52.89 ? 402 MET A N 1 ATOM 3197 C CA . MET A 1 398 ? 4.493 42.336 -7.870 1.00 53.45 ? 402 MET A CA 1 ATOM 3198 C C . MET A 1 398 ? 4.375 41.672 -6.491 1.00 52.85 ? 402 MET A C 1 ATOM 3199 O O . MET A 1 398 ? 3.418 41.938 -5.753 1.00 53.03 ? 402 MET A O 1 ATOM 3200 C CB . MET A 1 398 ? 3.795 43.700 -7.835 1.00 53.42 ? 402 MET A CB 1 ATOM 3201 C CG . MET A 1 398 ? 4.050 44.606 -9.024 1.00 54.20 ? 402 MET A CG 1 ATOM 3202 S SD . MET A 1 398 ? 2.740 45.851 -9.154 1.00 55.81 ? 402 MET A SD 1 ATOM 3203 C CE . MET A 1 398 ? 3.206 47.071 -7.921 1.00 55.47 ? 402 MET A CE 1 ATOM 3204 N N . ASN A 1 399 ? 5.344 40.830 -6.130 1.00 52.27 ? 403 ASN A N 1 ATOM 3205 C CA . ASN A 1 399 ? 5.380 40.243 -4.781 1.00 51.77 ? 403 ASN A CA 1 ATOM 3206 C C . ASN A 1 399 ? 5.563 41.303 -3.692 1.00 51.53 ? 403 ASN A C 1 ATOM 3207 O O . ASN A 1 399 ? 5.718 42.483 -4.009 1.00 51.55 ? 403 ASN A O 1 ATOM 3208 C CB . ASN A 1 399 ? 6.450 39.147 -4.668 1.00 51.86 ? 403 ASN A CB 1 ATOM 3209 C CG . ASN A 1 399 ? 7.838 39.608 -5.118 1.00 51.90 ? 403 ASN A CG 1 ATOM 3210 O OD1 . ASN A 1 399 ? 8.356 40.641 -4.678 1.00 51.89 ? 403 ASN A OD1 1 ATOM 3211 N ND2 . ASN A 1 399 ? 8.455 38.815 -5.985 1.00 52.06 ? 403 ASN A ND2 1 ATOM 3212 N N . VAL A 1 400 ? 5.553 40.894 -2.420 1.00 51.13 ? 404 VAL A N 1 ATOM 3213 C CA . VAL A 1 400 ? 5.662 41.852 -1.308 1.00 50.88 ? 404 VAL A CA 1 ATOM 3214 C C . VAL A 1 400 ? 6.951 42.670 -1.334 1.00 51.00 ? 404 VAL A C 1 ATOM 3215 O O . VAL A 1 400 ? 7.025 43.748 -0.727 1.00 51.42 ? 404 VAL A O 1 ATOM 3216 C CB . VAL A 1 400 ? 5.531 41.199 0.086 1.00 50.79 ? 404 VAL A CB 1 ATOM 3217 C CG1 . VAL A 1 400 ? 4.099 40.932 0.404 1.00 50.60 ? 404 VAL A CG1 1 ATOM 3218 C CG2 . VAL A 1 400 ? 6.388 39.937 0.211 1.00 50.90 ? 404 VAL A CG2 1 ATOM 3219 N N . SER A 1 401 ? 7.958 42.156 -2.032 1.00 50.64 ? 405 SER A N 1 ATOM 3220 C CA . SER A 1 401 ? 9.231 42.844 -2.167 1.00 50.47 ? 405 SER A CA 1 ATOM 3221 C C . SER A 1 401 ? 9.175 44.036 -3.141 1.00 50.14 ? 405 SER A C 1 ATOM 3222 O O . SER A 1 401 ? 10.083 44.864 -3.153 1.00 50.19 ? 405 SER A O 1 ATOM 3223 C CB . SER A 1 401 ? 10.314 41.849 -2.576 1.00 50.57 ? 405 SER A CB 1 ATOM 3224 O OG . SER A 1 401 ? 11.350 42.497 -3.288 1.00 51.52 ? 405 SER A OG 1 ATOM 3225 N N . VAL A 1 402 ? 8.120 44.124 -3.949 1.00 49.66 ? 406 VAL A N 1 ATOM 3226 C CA . VAL A 1 402 ? 7.940 45.265 -4.854 1.00 49.12 ? 406 VAL A CA 1 ATOM 3227 C C . VAL A 1 402 ? 7.110 46.376 -4.199 1.00 48.83 ? 406 VAL A C 1 ATOM 3228 O O . VAL A 1 402 ? 5.920 46.194 -3.929 1.00 48.88 ? 406 VAL A O 1 ATOM 3229 C CB . VAL A 1 402 ? 7.321 44.842 -6.213 1.00 49.13 ? 406 VAL A CB 1 ATOM 3230 C CG1 . VAL A 1 402 ? 7.065 46.054 -7.094 1.00 48.64 ? 406 VAL A CG1 1 ATOM 3231 C CG2 . VAL A 1 402 ? 8.231 43.856 -6.935 1.00 49.01 ? 406 VAL A CG2 1 ATOM 3232 N N . LYS A 1 403 ? 7.752 47.521 -3.963 1.00 48.33 ? 407 LYS A N 1 ATOM 3233 C CA . LYS A 1 403 ? 7.133 48.668 -3.286 1.00 47.87 ? 407 LYS A CA 1 ATOM 3234 C C . LYS A 1 403 ? 6.118 49.443 -4.139 1.00 47.49 ? 407 LYS A C 1 ATOM 3235 O O . LYS A 1 403 ? 6.347 49.716 -5.317 1.00 47.29 ? 407 LYS A O 1 ATOM 3236 C CB . LYS A 1 403 ? 8.202 49.650 -2.807 1.00 47.90 ? 407 LYS A CB 1 ATOM 3237 C CG . LYS A 1 403 ? 9.120 49.144 -1.719 1.00 48.47 ? 407 LYS A CG 1 ATOM 3238 C CD . LYS A 1 403 ? 9.657 50.318 -0.895 1.00 48.63 ? 407 LYS A CD 1 ATOM 3239 C CE . LYS A 1 403 ? 10.970 49.980 -0.203 1.00 48.48 ? 407 LYS A CE 1 ATOM 3240 N NZ . LYS A 1 403 ? 12.141 50.025 -1.137 1.00 48.48 ? 407 LYS A NZ 1 ATOM 3241 N N . SER A 1 404 ? 4.999 49.802 -3.523 1.00 47.02 ? 408 SER A N 1 ATOM 3242 C CA . SER A 1 404 ? 4.060 50.747 -4.114 1.00 46.50 ? 408 SER A CA 1 ATOM 3243 C C . SER A 1 404 ? 3.998 52.004 -3.242 1.00 46.18 ? 408 SER A C 1 ATOM 3244 O O . SER A 1 404 ? 4.397 51.976 -2.060 1.00 46.05 ? 408 SER A O 1 ATOM 3245 C CB . SER A 1 404 ? 2.663 50.123 -4.245 1.00 46.58 ? 408 SER A CB 1 ATOM 3246 O OG . SER A 1 404 ? 2.584 49.276 -5.380 1.00 46.86 ? 408 SER A OG 1 ATOM 3247 N N . GLY A 1 405 ? 3.512 53.104 -3.823 1.00 45.35 ? 409 GLY A N 1 ATOM 3248 C CA . GLY A 1 405 ? 3.252 54.308 -3.056 1.00 44.45 ? 409 GLY A CA 1 ATOM 3249 C C . GLY A 1 405 ? 2.511 53.907 -1.794 1.00 43.98 ? 409 GLY A C 1 ATOM 3250 O O . GLY A 1 405 ? 2.978 54.152 -0.676 1.00 44.01 ? 409 GLY A O 1 ATOM 3251 N N . LEU A 1 406 ? 1.370 53.253 -1.989 1.00 43.37 ? 410 LEU A N 1 ATOM 3252 C CA . LEU A 1 406 ? 0.552 52.750 -0.892 1.00 42.75 ? 410 LEU A CA 1 ATOM 3253 C C . LEU A 1 406 ? 0.463 51.228 -0.935 1.00 42.30 ? 410 LEU A C 1 ATOM 3254 O O . LEU A 1 406 ? -0.320 50.661 -1.704 1.00 42.75 ? 410 LEU A O 1 ATOM 3255 C CB . LEU A 1 406 ? -0.844 53.375 -0.949 1.00 42.59 ? 410 LEU A CB 1 ATOM 3256 C CG . LEU A 1 406 ? -1.127 54.594 -0.069 1.00 42.84 ? 410 LEU A CG 1 ATOM 3257 C CD1 . LEU A 1 406 ? 0.126 55.177 0.554 1.00 43.05 ? 410 LEU A CD1 1 ATOM 3258 C CD2 . LEU A 1 406 ? -1.890 55.648 -0.841 1.00 42.64 ? 410 LEU A CD2 1 ATOM 3259 N N . GLY A 1 407 ? 1.278 50.568 -0.119 1.00 41.43 ? 411 GLY A N 1 ATOM 3260 C CA . GLY A 1 407 ? 1.282 49.120 -0.065 1.00 40.48 ? 411 GLY A CA 1 ATOM 3261 C C . GLY A 1 407 ? 2.553 48.487 -0.596 1.00 40.17 ? 411 GLY A C 1 ATOM 3262 O O . GLY A 1 407 ? 3.360 49.150 -1.248 1.00 39.98 ? 411 GLY A O 1 ATOM 3263 N N . PRO A 1 408 ? 2.738 47.181 -0.327 1.00 40.00 ? 412 PRO A N 1 ATOM 3264 C CA . PRO A 1 408 ? 1.806 46.297 0.371 1.00 39.70 ? 412 PRO A CA 1 ATOM 3265 C C . PRO A 1 408 ? 1.721 46.558 1.871 1.00 39.47 ? 412 PRO A C 1 ATOM 3266 O O . PRO A 1 408 ? 2.736 46.825 2.503 1.00 39.66 ? 412 PRO A O 1 ATOM 3267 C CB . PRO A 1 408 ? 2.425 44.925 0.146 1.00 39.52 ? 412 PRO A CB 1 ATOM 3268 C CG . PRO A 1 408 ? 3.871 45.198 0.071 1.00 39.75 ? 412 PRO A CG 1 ATOM 3269 C CD . PRO A 1 408 ? 3.960 46.458 -0.720 1.00 40.04 ? 412 PRO A CD 1 ATOM 3270 N N . PHE A 1 409 ? 0.518 46.490 2.426 1.00 39.05 ? 413 PHE A N 1 ATOM 3271 C CA . PHE A 1 409 ? 0.358 46.407 3.875 1.00 39.19 ? 413 PHE A CA 1 ATOM 3272 C C . PHE A 1 409 ? -0.767 45.432 4.218 1.00 39.53 ? 413 PHE A C 1 ATOM 3273 O O . PHE A 1 409 ? -1.802 45.395 3.544 1.00 39.86 ? 413 PHE A O 1 ATOM 3274 C CB . PHE A 1 409 ? 0.134 47.789 4.526 1.00 38.77 ? 413 PHE A CB 1 ATOM 3275 C CG . PHE A 1 409 ? -1.073 48.528 4.011 1.00 38.29 ? 413 PHE A CG 1 ATOM 3276 C CD1 . PHE A 1 409 ? -2.340 48.277 4.529 1.00 37.53 ? 413 PHE A CD1 1 ATOM 3277 C CD2 . PHE A 1 409 ? -0.939 49.489 3.014 1.00 37.87 ? 413 PHE A CD2 1 ATOM 3278 C CE1 . PHE A 1 409 ? -3.457 48.958 4.049 1.00 37.40 ? 413 PHE A CE1 1 ATOM 3279 C CE2 . PHE A 1 409 ? -2.046 50.174 2.532 1.00 37.35 ? 413 PHE A CE2 1 ATOM 3280 C CZ . PHE A 1 409 ? -3.310 49.908 3.056 1.00 37.80 ? 413 PHE A CZ 1 ATOM 3281 N N . GLY A 1 410 ? -0.562 44.639 5.262 1.00 39.61 ? 414 GLY A N 1 ATOM 3282 C CA . GLY A 1 410 ? -1.549 43.649 5.650 1.00 39.56 ? 414 GLY A CA 1 ATOM 3283 C C . GLY A 1 410 ? -0.978 42.749 6.706 1.00 39.68 ? 414 GLY A C 1 ATOM 3284 O O . GLY A 1 410 ? -0.435 43.234 7.693 1.00 39.66 ? 414 GLY A O 1 ATOM 3285 N N . LEU A 1 411 ? -1.081 41.439 6.486 1.00 39.78 ? 415 LEU A N 1 ATOM 3286 C CA . LEU A 1 411 ? -0.677 40.449 7.484 1.00 39.84 ? 415 LEU A CA 1 ATOM 3287 C C . LEU A 1 411 ? 0.256 39.358 6.946 1.00 40.31 ? 415 LEU A C 1 ATOM 3288 O O . LEU A 1 411 ? -0.018 38.774 5.903 1.00 40.64 ? 415 LEU A O 1 ATOM 3289 C CB . LEU A 1 411 ? -1.920 39.796 8.097 1.00 39.43 ? 415 LEU A CB 1 ATOM 3290 C CG . LEU A 1 411 ? -2.983 40.696 8.737 1.00 39.02 ? 415 LEU A CG 1 ATOM 3291 C CD1 . LEU A 1 411 ? -4.237 39.907 9.101 1.00 37.54 ? 415 LEU A CD1 1 ATOM 3292 C CD2 . LEU A 1 411 ? -2.419 41.418 9.955 1.00 38.80 ? 415 LEU A CD2 1 ATOM 3293 N N . MET A 1 412 ? 1.363 39.097 7.643 1.00 40.72 ? 416 MET A N 1 ATOM 3294 C CA . MET A 1 412 ? 2.070 37.828 7.476 1.00 40.93 ? 416 MET A CA 1 ATOM 3295 C C . MET A 1 412 ? 1.357 36.875 8.407 1.00 40.59 ? 416 MET A C 1 ATOM 3296 O O . MET A 1 412 ? 1.263 37.135 9.603 1.00 40.62 ? 416 MET A O 1 ATOM 3297 C CB . MET A 1 412 ? 3.536 37.904 7.913 1.00 41.85 ? 416 MET A CB 1 ATOM 3298 C CG . MET A 1 412 ? 4.340 39.116 7.460 1.00 43.12 ? 416 MET A CG 1 ATOM 3299 S SD . MET A 1 412 ? 4.745 39.093 5.714 1.00 48.85 ? 416 MET A SD 1 ATOM 3300 C CE . MET A 1 412 ? 6.221 40.100 5.724 1.00 45.52 ? 416 MET A CE 1 ATOM 3301 N N . VAL A 1 413 ? 0.827 35.791 7.864 1.00 40.48 ? 417 VAL A N 1 ATOM 3302 C CA . VAL A 1 413 ? 0.195 34.754 8.686 1.00 40.35 ? 417 VAL A CA 1 ATOM 3303 C C . VAL A 1 413 ? 0.951 33.450 8.478 1.00 40.40 ? 417 VAL A C 1 ATOM 3304 O O . VAL A 1 413 ? 1.738 33.338 7.539 1.00 40.06 ? 417 VAL A O 1 ATOM 3305 C CB . VAL A 1 413 ? -1.323 34.585 8.384 1.00 40.18 ? 417 VAL A CB 1 ATOM 3306 C CG1 . VAL A 1 413 ? -2.055 35.906 8.565 1.00 40.16 ? 417 VAL A CG1 1 ATOM 3307 C CG2 . VAL A 1 413 ? -1.556 34.052 6.977 1.00 40.23 ? 417 VAL A CG2 1 ATOM 3308 N N . LEU A 1 414 ? 0.719 32.483 9.359 1.00 40.83 ? 418 LEU A N 1 ATOM 3309 C CA . LEU A 1 414 ? 1.423 31.199 9.330 1.00 41.56 ? 418 LEU A CA 1 ATOM 3310 C C . LEU A 1 414 ? 2.899 31.391 8.970 1.00 42.51 ? 418 LEU A C 1 ATOM 3311 O O . LEU A 1 414 ? 3.417 30.797 8.014 1.00 42.63 ? 418 LEU A O 1 ATOM 3312 C CB . LEU A 1 414 ? 0.721 30.200 8.401 1.00 41.06 ? 418 LEU A CB 1 ATOM 3313 C CG . LEU A 1 414 ? -0.725 29.840 8.772 1.00 40.77 ? 418 LEU A CG 1 ATOM 3314 C CD1 . LEU A 1 414 ? -1.361 28.993 7.693 1.00 40.91 ? 418 LEU A CD1 1 ATOM 3315 C CD2 . LEU A 1 414 ? -0.832 29.139 10.116 1.00 39.01 ? 418 LEU A CD2 1 ATOM 3316 N N . ALA A 1 415 ? 3.558 32.238 9.760 1.00 43.52 ? 419 ALA A N 1 ATOM 3317 C CA . ALA A 1 415 ? 4.917 32.677 9.496 1.00 44.50 ? 419 ALA A CA 1 ATOM 3318 C C . ALA A 1 415 ? 5.896 32.052 10.473 1.00 45.49 ? 419 ALA A C 1 ATOM 3319 O O . ALA A 1 415 ? 5.564 31.810 11.636 1.00 45.47 ? 419 ALA A O 1 ATOM 3320 C CB . ALA A 1 415 ? 4.997 34.190 9.565 1.00 44.20 ? 419 ALA A CB 1 ATOM 3321 N N . SER A 1 416 ? 7.103 31.786 9.983 1.00 46.95 ? 420 SER A N 1 ATOM 3322 C CA . SER A 1 416 ? 8.193 31.257 10.801 1.00 48.23 ? 420 SER A CA 1 ATOM 3323 C C . SER A 1 416 ? 8.888 32.395 11.555 1.00 49.40 ? 420 SER A C 1 ATOM 3324 O O . SER A 1 416 ? 8.881 33.549 11.109 1.00 49.31 ? 420 SER A O 1 ATOM 3325 C CB . SER A 1 416 ? 9.196 30.521 9.921 1.00 47.94 ? 420 SER A CB 1 ATOM 3326 O OG . SER A 1 416 ? 9.736 31.404 8.957 1.00 47.92 ? 420 SER A OG 1 ATOM 3327 N N . LYS A 1 417 ? 9.486 32.055 12.697 1.00 51.05 ? 421 LYS A N 1 ATOM 3328 C CA . LYS A 1 417 ? 10.135 33.033 13.581 1.00 52.41 ? 421 LYS A CA 1 ATOM 3329 C C . LYS A 1 417 ? 10.873 34.096 12.767 1.00 52.89 ? 421 LYS A C 1 ATOM 3330 O O . LYS A 1 417 ? 10.640 35.295 12.935 1.00 53.05 ? 421 LYS A O 1 ATOM 3331 C CB . LYS A 1 417 ? 11.113 32.334 14.544 1.00 52.97 ? 421 LYS A CB 1 ATOM 3332 C CG . LYS A 1 417 ? 10.600 31.012 15.180 1.00 54.34 ? 421 LYS A CG 1 ATOM 3333 C CD . LYS A 1 417 ? 10.235 31.163 16.670 1.00 55.38 ? 421 LYS A CD 1 ATOM 3334 C CE . LYS A 1 417 ? 9.622 29.872 17.235 1.00 54.66 ? 421 LYS A CE 1 ATOM 3335 N NZ . LYS A 1 417 ? 8.867 30.102 18.506 1.00 54.69 ? 421 LYS A NZ 1 ATOM 3336 N N . ASN A 1 418 ? 11.730 33.637 11.855 1.00 53.46 ? 422 ASN A N 1 ATOM 3337 C CA . ASN A 1 418 ? 12.589 34.514 11.055 1.00 53.69 ? 422 ASN A CA 1 ATOM 3338 C C . ASN A 1 418 ? 12.110 34.703 9.615 1.00 53.37 ? 422 ASN A C 1 ATOM 3339 O O . ASN A 1 418 ? 12.904 35.026 8.727 1.00 53.47 ? 422 ASN A O 1 ATOM 3340 C CB . ASN A 1 418 ? 14.023 33.975 11.067 1.00 54.07 ? 422 ASN A CB 1 ATOM 3341 C CG . ASN A 1 418 ? 14.550 33.767 12.474 1.00 55.18 ? 422 ASN A CG 1 ATOM 3342 O OD1 . ASN A 1 418 ? 14.964 34.723 13.147 1.00 56.52 ? 422 ASN A OD1 1 ATOM 3343 N ND2 . ASN A 1 418 ? 14.529 32.514 12.933 1.00 55.35 ? 422 ASN A ND2 1 ATOM 3344 N N . LEU A 1 419 ? 10.816 34.486 9.391 1.00 52.85 ? 423 LEU A N 1 ATOM 3345 C CA . LEU A 1 419 ? 10.173 34.749 8.097 1.00 52.34 ? 423 LEU A CA 1 ATOM 3346 C C . LEU A 1 419 ? 10.758 33.988 6.908 1.00 51.71 ? 423 LEU A C 1 ATOM 3347 O O . LEU A 1 419 ? 10.763 34.490 5.782 1.00 51.69 ? 423 LEU A O 1 ATOM 3348 C CB . LEU A 1 419 ? 10.109 36.254 7.806 1.00 52.41 ? 423 LEU A CB 1 ATOM 3349 C CG . LEU A 1 419 ? 9.012 36.981 8.591 1.00 53.10 ? 423 LEU A CG 1 ATOM 3350 C CD1 . LEU A 1 419 ? 9.546 37.604 9.878 1.00 53.52 ? 423 LEU A CD1 1 ATOM 3351 C CD2 . LEU A 1 419 ? 8.390 38.036 7.711 1.00 53.72 ? 423 LEU A CD2 1 ATOM 3352 N N . GLU A 1 420 ? 11.249 32.780 7.162 1.00 51.02 ? 424 GLU A N 1 ATOM 3353 C CA . GLU A 1 420 ? 11.600 31.863 6.082 1.00 50.60 ? 424 GLU A CA 1 ATOM 3354 C C . GLU A 1 420 ? 10.305 31.434 5.381 1.00 49.78 ? 424 GLU A C 1 ATOM 3355 O O . GLU A 1 420 ? 10.247 31.356 4.147 1.00 49.75 ? 424 GLU A O 1 ATOM 3356 C CB . GLU A 1 420 ? 12.353 30.633 6.609 1.00 50.91 ? 424 GLU A CB 1 ATOM 3357 C CG . GLU A 1 420 ? 13.612 30.934 7.425 1.00 52.75 ? 424 GLU A CG 1 ATOM 3358 C CD . GLU A 1 420 ? 13.373 30.913 8.935 1.00 55.43 ? 424 GLU A CD 1 ATOM 3359 O OE1 . GLU A 1 420 ? 14.146 30.231 9.644 1.00 56.97 ? 424 GLU A OE1 1 ATOM 3360 O OE2 . GLU A 1 420 ? 12.423 31.571 9.420 1.00 56.57 ? 424 GLU A OE2 1 ATOM 3361 N N . GLU A 1 421 ? 9.271 31.174 6.183 1.00 48.45 ? 425 GLU A N 1 ATOM 3362 C CA . GLU A 1 421 ? 7.935 30.895 5.679 1.00 47.22 ? 425 GLU A CA 1 ATOM 3363 C C . GLU A 1 421 ? 6.964 31.956 6.156 1.00 46.30 ? 425 GLU A C 1 ATOM 3364 O O . GLU A 1 421 ? 6.979 32.316 7.335 1.00 46.31 ? 425 GLU A O 1 ATOM 3365 C CB . GLU A 1 421 ? 7.438 29.546 6.183 1.00 47.34 ? 425 GLU A CB 1 ATOM 3366 C CG . GLU A 1 421 ? 8.098 28.342 5.565 1.00 47.48 ? 425 GLU A CG 1 ATOM 3367 C CD . GLU A 1 421 ? 7.572 27.045 6.144 1.00 47.88 ? 425 GLU A CD 1 ATOM 3368 O OE1 . GLU A 1 421 ? 7.146 27.026 7.320 1.00 46.99 ? 425 GLU A OE1 1 ATOM 3369 O OE2 . GLU A 1 421 ? 7.585 26.038 5.414 1.00 49.13 ? 425 GLU A OE2 1 ATOM 3370 N N . TYR A 1 422 ? 6.129 32.446 5.239 1.00 45.01 ? 426 TYR A N 1 ATOM 3371 C CA . TYR A 1 422 ? 5.003 33.323 5.568 1.00 43.89 ? 426 TYR A CA 1 ATOM 3372 C C . TYR A 1 422 ? 4.002 33.402 4.424 1.00 43.10 ? 426 TYR A C 1 ATOM 3373 O O . TYR A 1 422 ? 4.365 33.278 3.248 1.00 42.95 ? 426 TYR A O 1 ATOM 3374 C CB . TYR A 1 422 ? 5.466 34.739 5.948 1.00 43.97 ? 426 TYR A CB 1 ATOM 3375 C CG . TYR A 1 422 ? 6.303 35.408 4.892 1.00 44.42 ? 426 TYR A CG 1 ATOM 3376 C CD1 . TYR A 1 422 ? 5.711 36.083 3.822 1.00 44.70 ? 426 TYR A CD1 1 ATOM 3377 C CD2 . TYR A 1 422 ? 7.696 35.365 4.957 1.00 44.97 ? 426 TYR A CD2 1 ATOM 3378 C CE1 . TYR A 1 422 ? 6.489 36.689 2.840 1.00 45.20 ? 426 TYR A CE1 1 ATOM 3379 C CE2 . TYR A 1 422 ? 8.481 35.974 3.985 1.00 44.88 ? 426 TYR A CE2 1 ATOM 3380 C CZ . TYR A 1 422 ? 7.874 36.629 2.931 1.00 44.82 ? 426 TYR A CZ 1 ATOM 3381 O OH . TYR A 1 422 ? 8.654 37.223 1.971 1.00 44.86 ? 426 TYR A OH 1 ATOM 3382 N N . THR A 1 423 ? 2.744 33.632 4.788 1.00 42.10 ? 427 THR A N 1 ATOM 3383 C CA . THR A 1 423 ? 1.672 33.877 3.833 1.00 41.04 ? 427 THR A CA 1 ATOM 3384 C C . THR A 1 423 ? 1.229 35.324 4.005 1.00 40.31 ? 427 THR A C 1 ATOM 3385 O O . THR A 1 423 ? 0.847 35.711 5.103 1.00 40.40 ? 427 THR A O 1 ATOM 3386 C CB . THR A 1 423 ? 0.499 32.895 4.066 1.00 40.83 ? 427 THR A CB 1 ATOM 3387 O OG1 . THR A 1 423 ? 0.929 31.569 3.745 1.00 40.82 ? 427 THR A OG1 1 ATOM 3388 C CG2 . THR A 1 423 ? -0.693 33.237 3.193 1.00 40.82 ? 427 THR A CG2 1 ATOM 3389 N N . SER A 1 424 ? 1.300 36.119 2.935 1.00 39.46 ? 428 SER A N 1 ATOM 3390 C CA . SER A 1 424 ? 0.963 37.549 3.014 1.00 39.14 ? 428 SER A CA 1 ATOM 3391 C C . SER A 1 424 ? -0.442 37.791 2.518 1.00 39.04 ? 428 SER A C 1 ATOM 3392 O O . SER A 1 424 ? -0.786 37.417 1.396 1.00 39.22 ? 428 SER A O 1 ATOM 3393 C CB . SER A 1 424 ? 1.908 38.443 2.192 1.00 38.87 ? 428 SER A CB 1 ATOM 3394 O OG . SER A 1 424 ? 3.187 37.878 1.986 1.00 39.57 ? 428 SER A OG 1 ATOM 3395 N N . VAL A 1 425 ? -1.255 38.428 3.346 1.00 38.84 ? 429 VAL A N 1 ATOM 3396 C CA . VAL A 1 425 ? -2.572 38.858 2.912 1.00 38.76 ? 429 VAL A CA 1 ATOM 3397 C C . VAL A 1 425 ? -2.601 40.371 3.035 1.00 38.92 ? 429 VAL A C 1 ATOM 3398 O O . VAL A 1 425 ? -2.655 40.909 4.146 1.00 39.26 ? 429 VAL A O 1 ATOM 3399 C CB . VAL A 1 425 ? -3.691 38.213 3.741 1.00 38.83 ? 429 VAL A CB 1 ATOM 3400 C CG1 . VAL A 1 425 ? -5.041 38.659 3.210 1.00 38.98 ? 429 VAL A CG1 1 ATOM 3401 C CG2 . VAL A 1 425 ? -3.572 36.680 3.718 1.00 38.07 ? 429 VAL A CG2 1 ATOM 3402 N N . TYR A 1 426 ? -2.544 41.055 1.893 1.00 38.80 ? 430 TYR A N 1 ATOM 3403 C CA . TYR A 1 426 ? -2.268 42.491 1.891 1.00 38.48 ? 430 TYR A CA 1 ATOM 3404 C C . TYR A 1 426 ? -3.067 43.322 0.886 1.00 38.29 ? 430 TYR A C 1 ATOM 3405 O O . TYR A 1 426 ? -3.771 42.775 0.044 1.00 37.97 ? 430 TYR A O 1 ATOM 3406 C CB . TYR A 1 426 ? -0.765 42.740 1.709 1.00 38.19 ? 430 TYR A CB 1 ATOM 3407 C CG . TYR A 1 426 ? -0.199 42.408 0.342 1.00 38.22 ? 430 TYR A CG 1 ATOM 3408 C CD1 . TYR A 1 426 ? -0.443 43.228 -0.764 1.00 38.06 ? 430 TYR A CD1 1 ATOM 3409 C CD2 . TYR A 1 426 ? 0.621 41.293 0.162 1.00 37.59 ? 430 TYR A CD2 1 ATOM 3410 C CE1 . TYR A 1 426 ? 0.100 42.931 -2.010 1.00 37.55 ? 430 TYR A CE1 1 ATOM 3411 C CE2 . TYR A 1 426 ? 1.171 40.991 -1.078 1.00 36.26 ? 430 TYR A CE2 1 ATOM 3412 C CZ . TYR A 1 426 ? 0.908 41.813 -2.153 1.00 37.74 ? 430 TYR A CZ 1 ATOM 3413 O OH . TYR A 1 426 ? 1.447 41.507 -3.381 1.00 38.98 ? 430 TYR A OH 1 ATOM 3414 N N . PHE A 1 427 ? -2.932 44.647 1.005 1.00 38.25 ? 431 PHE A N 1 ATOM 3415 C CA . PHE A 1 427 ? -3.531 45.619 0.104 1.00 38.08 ? 431 PHE A CA 1 ATOM 3416 C C . PHE A 1 427 ? -2.471 46.411 -0.639 1.00 38.52 ? 431 PHE A C 1 ATOM 3417 O O . PHE A 1 427 ? -1.356 46.568 -0.158 1.00 38.56 ? 431 PHE A O 1 ATOM 3418 C CB . PHE A 1 427 ? -4.383 46.622 0.881 1.00 37.82 ? 431 PHE A CB 1 ATOM 3419 C CG . PHE A 1 427 ? -5.625 46.040 1.498 1.00 37.19 ? 431 PHE A CG 1 ATOM 3420 C CD1 . PHE A 1 427 ? -6.623 45.472 0.706 1.00 36.71 ? 431 PHE A CD1 1 ATOM 3421 C CD2 . PHE A 1 427 ? -5.817 46.099 2.869 1.00 36.57 ? 431 PHE A CD2 1 ATOM 3422 C CE1 . PHE A 1 427 ? -7.777 44.943 1.274 1.00 35.98 ? 431 PHE A CE1 1 ATOM 3423 C CE2 . PHE A 1 427 ? -6.976 45.582 3.447 1.00 37.04 ? 431 PHE A CE2 1 ATOM 3424 C CZ . PHE A 1 427 ? -7.958 45.001 2.643 1.00 36.85 ? 431 PHE A CZ 1 ATOM 3425 N N . ARG A 1 428 ? -2.835 46.892 -1.825 1.00 39.14 ? 432 ARG A N 1 ATOM 3426 C CA . ARG A 1 428 ? -2.162 48.015 -2.482 1.00 39.51 ? 432 ARG A CA 1 ATOM 3427 C C . ARG A 1 428 ? -3.256 49.003 -2.887 1.00 39.92 ? 432 ARG A C 1 ATOM 3428 O O . ARG A 1 428 ? -4.376 48.580 -3.192 1.00 40.07 ? 432 ARG A O 1 ATOM 3429 C CB . ARG A 1 428 ? -1.445 47.556 -3.744 1.00 39.62 ? 432 ARG A CB 1 ATOM 3430 C CG . ARG A 1 428 ? -0.358 46.524 -3.563 1.00 39.55 ? 432 ARG A CG 1 ATOM 3431 C CD . ARG A 1 428 ? 0.452 46.435 -4.846 1.00 39.58 ? 432 ARG A CD 1 ATOM 3432 N NE . ARG A 1 428 ? 1.433 45.356 -4.818 1.00 40.60 ? 432 ARG A NE 1 ATOM 3433 C CZ . ARG A 1 428 ? 2.714 45.499 -4.481 1.00 40.89 ? 432 ARG A CZ 1 ATOM 3434 N NH1 . ARG A 1 428 ? 3.204 46.687 -4.130 1.00 40.48 ? 432 ARG A NH1 1 ATOM 3435 N NH2 . ARG A 1 428 ? 3.511 44.440 -4.500 1.00 41.55 ? 432 ARG A NH2 1 ATOM 3436 N N . ILE A 1 429 ? -2.953 50.302 -2.900 1.00 40.08 ? 433 ILE A N 1 ATOM 3437 C CA . ILE A 1 429 ? -3.927 51.311 -3.364 1.00 40.54 ? 433 ILE A CA 1 ATOM 3438 C C . ILE A 1 429 ? -3.428 52.006 -4.625 1.00 40.82 ? 433 ILE A C 1 ATOM 3439 O O . ILE A 1 429 ? -2.277 52.392 -4.698 1.00 40.90 ? 433 ILE A O 1 ATOM 3440 C CB . ILE A 1 429 ? -4.217 52.411 -2.298 1.00 40.64 ? 433 ILE A CB 1 ATOM 3441 C CG1 . ILE A 1 429 ? -4.422 51.819 -0.901 1.00 40.52 ? 433 ILE A CG1 1 ATOM 3442 C CG2 . ILE A 1 429 ? -5.421 53.269 -2.700 1.00 40.22 ? 433 ILE A CG2 1 ATOM 3443 C CD1 . ILE A 1 429 ? -5.838 51.544 -0.568 1.00 40.61 ? 433 ILE A CD1 1 ATOM 3444 N N . PHE A 1 430 ? -4.301 52.167 -5.612 1.00 41.63 ? 434 PHE A N 1 ATOM 3445 C CA . PHE A 1 430 ? -3.963 52.903 -6.825 1.00 42.37 ? 434 PHE A CA 1 ATOM 3446 C C . PHE A 1 430 ? -4.947 54.046 -7.077 1.00 43.21 ? 434 PHE A C 1 ATOM 3447 O O . PHE A 1 430 ? -6.051 54.072 -6.516 1.00 43.25 ? 434 PHE A O 1 ATOM 3448 C CB . PHE A 1 430 ? -3.942 51.974 -8.037 1.00 42.08 ? 434 PHE A CB 1 ATOM 3449 C CG . PHE A 1 430 ? -2.983 50.823 -7.914 1.00 42.51 ? 434 PHE A CG 1 ATOM 3450 C CD1 . PHE A 1 430 ? -1.628 50.997 -8.159 1.00 42.20 ? 434 PHE A CD1 1 ATOM 3451 C CD2 . PHE A 1 430 ? -3.441 49.550 -7.573 1.00 43.04 ? 434 PHE A CD2 1 ATOM 3452 C CE1 . PHE A 1 430 ? -0.742 49.930 -8.059 1.00 41.49 ? 434 PHE A CE1 1 ATOM 3453 C CE2 . PHE A 1 430 ? -2.555 48.477 -7.463 1.00 41.90 ? 434 PHE A CE2 1 ATOM 3454 C CZ . PHE A 1 430 ? -1.205 48.671 -7.712 1.00 41.61 ? 434 PHE A CZ 1 ATOM 3455 N N . LYS A 1 431 ? -4.535 55.001 -7.909 1.00 44.13 ? 435 LYS A N 1 ATOM 3456 C CA . LYS A 1 431 ? -5.454 56.005 -8.421 1.00 45.23 ? 435 LYS A CA 1 ATOM 3457 C C . LYS A 1 431 ? -5.960 55.478 -9.759 1.00 45.17 ? 435 LYS A C 1 ATOM 3458 O O . LYS A 1 431 ? -5.177 54.989 -10.571 1.00 44.70 ? 435 LYS A O 1 ATOM 3459 C CB . LYS A 1 431 ? -4.767 57.368 -8.572 1.00 45.10 ? 435 LYS A CB 1 ATOM 3460 C CG . LYS A 1 431 ? -5.751 58.554 -8.715 1.00 47.01 ? 435 LYS A CG 1 ATOM 3461 C CD . LYS A 1 431 ? -5.072 59.885 -9.145 1.00 46.93 ? 435 LYS A CD 1 ATOM 3462 C CE . LYS A 1 431 ? -4.289 60.568 -7.981 1.00 49.85 ? 435 LYS A CE 1 ATOM 3463 N NZ . LYS A 1 431 ? -3.705 61.914 -8.351 1.00 49.25 ? 435 LYS A NZ 1 ATOM 3464 N N . ALA A 1 432 ? -7.272 55.550 -9.966 1.00 45.84 ? 436 ALA A N 1 ATOM 3465 C CA . ALA A 1 432 ? -7.899 55.012 -11.172 1.00 46.70 ? 436 ALA A CA 1 ATOM 3466 C C . ALA A 1 432 ? -7.630 55.869 -12.412 1.00 47.43 ? 436 ALA A C 1 ATOM 3467 O O . ALA A 1 432 ? -7.454 57.090 -12.314 1.00 47.48 ? 436 ALA A O 1 ATOM 3468 C CB . ALA A 1 432 ? -9.390 54.832 -10.957 1.00 46.66 ? 436 ALA A CB 1 ATOM 3469 N N . ARG A 1 433 ? -7.614 55.222 -13.578 1.00 48.29 ? 437 ARG A N 1 ATOM 3470 C CA . ARG A 1 433 ? -7.256 55.876 -14.850 1.00 49.21 ? 437 ARG A CA 1 ATOM 3471 C C . ARG A 1 433 ? -8.347 56.773 -15.461 1.00 49.98 ? 437 ARG A C 1 ATOM 3472 O O . ARG A 1 433 ? -8.481 56.831 -16.685 1.00 50.12 ? 437 ARG A O 1 ATOM 3473 C CB . ARG A 1 433 ? -6.875 54.812 -15.893 1.00 49.22 ? 437 ARG A CB 1 ATOM 3474 C CG . ARG A 1 433 ? -5.448 54.358 -15.871 1.00 47.99 ? 437 ARG A CG 1 ATOM 3475 C CD . ARG A 1 433 ? -4.560 55.290 -16.632 1.00 46.28 ? 437 ARG A CD 1 ATOM 3476 N NE . ARG A 1 433 ? -3.177 55.022 -16.267 1.00 46.79 ? 437 ARG A NE 1 ATOM 3477 C CZ . ARG A 1 433 ? -2.137 55.760 -16.631 1.00 46.54 ? 437 ARG A CZ 1 ATOM 3478 N NH1 . ARG A 1 433 ? -2.304 56.837 -17.391 1.00 46.72 ? 437 ARG A NH1 1 ATOM 3479 N NH2 . ARG A 1 433 ? -0.923 55.415 -16.226 1.00 46.19 ? 437 ARG A NH2 1 ATOM 3480 N N . GLN A 1 434 ? -9.118 57.475 -14.637 1.00 50.80 ? 438 GLN A N 1 ATOM 3481 C CA . GLN A 1 434 ? -10.255 58.236 -15.158 1.00 51.66 ? 438 GLN A CA 1 ATOM 3482 C C . GLN A 1 434 ? -10.391 59.628 -14.540 1.00 51.99 ? 438 GLN A C 1 ATOM 3483 O O . GLN A 1 434 ? -9.735 59.940 -13.551 1.00 52.11 ? 438 GLN A O 1 ATOM 3484 C CB . GLN A 1 434 ? -11.543 57.434 -14.982 1.00 51.80 ? 438 GLN A CB 1 ATOM 3485 C CG . GLN A 1 434 ? -11.927 57.212 -13.527 1.00 52.61 ? 438 GLN A CG 1 ATOM 3486 C CD . GLN A 1 434 ? -12.945 56.115 -13.363 1.00 53.78 ? 438 GLN A CD 1 ATOM 3487 O OE1 . GLN A 1 434 ? -13.332 55.781 -12.242 1.00 55.11 ? 438 GLN A OE1 1 ATOM 3488 N NE2 . GLN A 1 434 ? -13.384 55.536 -14.480 1.00 53.32 ? 438 GLN A NE2 1 ATOM 3489 N N . ASN A 1 435 ? -11.263 60.448 -15.121 1.00 52.46 ? 439 ASN A N 1 ATOM 3490 C CA . ASN A 1 435 ? -11.370 61.867 -14.761 1.00 53.02 ? 439 ASN A CA 1 ATOM 3491 C C . ASN A 1 435 ? -11.782 62.170 -13.317 1.00 53.17 ? 439 ASN A C 1 ATOM 3492 O O . ASN A 1 435 ? -11.340 63.167 -12.733 1.00 52.92 ? 439 ASN A O 1 ATOM 3493 C CB . ASN A 1 435 ? -12.280 62.591 -15.753 1.00 53.09 ? 439 ASN A CB 1 ATOM 3494 C CG . ASN A 1 435 ? -11.716 62.583 -17.159 1.00 53.40 ? 439 ASN A CG 1 ATOM 3495 O OD1 . ASN A 1 435 ? -10.500 62.670 -17.358 1.00 53.48 ? 439 ASN A OD1 1 ATOM 3496 N ND2 . ASN A 1 435 ? -12.596 62.475 -18.143 1.00 53.73 ? 439 ASN A ND2 1 ATOM 3497 N N . SER A 1 436 ? -12.619 61.297 -12.758 1.00 53.38 ? 440 SER A N 1 ATOM 3498 C CA . SER A 1 436 ? -13.011 61.352 -11.348 1.00 53.47 ? 440 SER A CA 1 ATOM 3499 C C . SER A 1 436 ? -11.826 61.030 -10.426 1.00 53.29 ? 440 SER A C 1 ATOM 3500 O O . SER A 1 436 ? -10.791 60.534 -10.876 1.00 53.72 ? 440 SER A O 1 ATOM 3501 C CB . SER A 1 436 ? -14.136 60.344 -11.100 1.00 53.58 ? 440 SER A CB 1 ATOM 3502 O OG . SER A 1 436 ? -13.665 59.020 -11.308 1.00 54.01 ? 440 SER A OG 1 ATOM 3503 N N . ASN A 1 437 ? -11.973 61.291 -9.134 1.00 52.83 ? 441 ASN A N 1 ATOM 3504 C CA . ASN A 1 437 ? -10.927 60.912 -8.195 1.00 52.50 ? 441 ASN A CA 1 ATOM 3505 C C . ASN A 1 437 ? -11.146 59.499 -7.627 1.00 51.72 ? 441 ASN A C 1 ATOM 3506 O O . ASN A 1 437 ? -10.948 59.257 -6.439 1.00 51.94 ? 441 ASN A O 1 ATOM 3507 C CB . ASN A 1 437 ? -10.777 61.970 -7.082 1.00 52.90 ? 441 ASN A CB 1 ATOM 3508 C CG . ASN A 1 437 ? -11.848 61.847 -5.991 1.00 54.02 ? 441 ASN A CG 1 ATOM 3509 O OD1 . ASN A 1 437 ? -12.998 61.465 -6.264 1.00 54.92 ? 441 ASN A OD1 1 ATOM 3510 N ND2 . ASN A 1 437 ? -11.469 62.168 -4.746 1.00 54.85 ? 441 ASN A ND2 1 ATOM 3511 N N . LYS A 1 438 ? -11.557 58.567 -8.479 1.00 50.59 ? 442 LYS A N 1 ATOM 3512 C CA . LYS A 1 438 ? -11.836 57.200 -8.045 1.00 49.69 ? 442 LYS A CA 1 ATOM 3513 C C . LYS A 1 438 ? -10.540 56.475 -7.663 1.00 48.57 ? 442 LYS A C 1 ATOM 3514 O O . LYS A 1 438 ? -9.478 56.761 -8.210 1.00 48.39 ? 442 LYS A O 1 ATOM 3515 C CB . LYS A 1 438 ? -12.612 56.461 -9.152 1.00 50.18 ? 442 LYS A CB 1 ATOM 3516 C CG . LYS A 1 438 ? -12.705 54.934 -9.048 1.00 51.47 ? 442 LYS A CG 1 ATOM 3517 C CD . LYS A 1 438 ? -13.772 54.485 -8.059 1.00 54.23 ? 442 LYS A CD 1 ATOM 3518 C CE . LYS A 1 438 ? -13.947 52.970 -8.078 1.00 55.07 ? 442 LYS A CE 1 ATOM 3519 N NZ . LYS A 1 438 ? -15.139 52.579 -7.265 1.00 56.06 ? 442 LYS A NZ 1 ATOM 3520 N N . TYR A 1 439 ? -10.626 55.557 -6.705 1.00 47.45 ? 443 TYR A N 1 ATOM 3521 C CA . TYR A 1 439 ? -9.465 54.735 -6.328 1.00 46.33 ? 443 TYR A CA 1 ATOM 3522 C C . TYR A 1 439 ? -9.670 53.243 -6.592 1.00 45.34 ? 443 TYR A C 1 ATOM 3523 O O . TYR A 1 439 ? -10.805 52.777 -6.763 1.00 45.58 ? 443 TYR A O 1 ATOM 3524 C CB . TYR A 1 439 ? -9.050 54.992 -4.875 1.00 46.28 ? 443 TYR A CB 1 ATOM 3525 C CG . TYR A 1 439 ? -8.389 56.329 -4.719 1.00 46.38 ? 443 TYR A CG 1 ATOM 3526 C CD1 . TYR A 1 439 ? -7.018 56.470 -4.897 1.00 47.02 ? 443 TYR A CD1 1 ATOM 3527 C CD2 . TYR A 1 439 ? -9.141 57.467 -4.438 1.00 46.20 ? 443 TYR A CD2 1 ATOM 3528 C CE1 . TYR A 1 439 ? -6.402 57.723 -4.782 1.00 47.12 ? 443 TYR A CE1 1 ATOM 3529 C CE2 . TYR A 1 439 ? -8.542 58.714 -4.322 1.00 46.38 ? 443 TYR A CE2 1 ATOM 3530 C CZ . TYR A 1 439 ? -7.176 58.837 -4.494 1.00 46.45 ? 443 TYR A CZ 1 ATOM 3531 O OH . TYR A 1 439 ? -6.586 60.071 -4.378 1.00 46.37 ? 443 TYR A OH 1 ATOM 3532 N N . VAL A 1 440 ? -8.561 52.509 -6.651 1.00 43.80 ? 444 VAL A N 1 ATOM 3533 C CA . VAL A 1 440 ? -8.594 51.069 -6.855 1.00 42.39 ? 444 VAL A CA 1 ATOM 3534 C C . VAL A 1 440 ? -7.887 50.389 -5.691 1.00 41.63 ? 444 VAL A C 1 ATOM 3535 O O . VAL A 1 440 ? -6.696 50.618 -5.461 1.00 41.11 ? 444 VAL A O 1 ATOM 3536 C CB . VAL A 1 440 ? -7.913 50.658 -8.180 1.00 42.24 ? 444 VAL A CB 1 ATOM 3537 C CG1 . VAL A 1 440 ? -7.996 49.170 -8.368 1.00 41.88 ? 444 VAL A CG1 1 ATOM 3538 C CG2 . VAL A 1 440 ? -8.542 51.370 -9.363 1.00 41.95 ? 444 VAL A CG2 1 ATOM 3539 N N . VAL A 1 441 ? -8.628 49.560 -4.960 1.00 40.76 ? 445 VAL A N 1 ATOM 3540 C CA . VAL A 1 441 ? -8.047 48.783 -3.863 1.00 39.95 ? 445 VAL A CA 1 ATOM 3541 C C . VAL A 1 441 ? -7.770 47.333 -4.281 1.00 39.32 ? 445 VAL A C 1 ATOM 3542 O O . VAL A 1 441 ? -8.657 46.615 -4.721 1.00 39.17 ? 445 VAL A O 1 ATOM 3543 C CB . VAL A 1 441 ? -8.901 48.858 -2.567 1.00 39.85 ? 445 VAL A CB 1 ATOM 3544 C CG1 . VAL A 1 441 ? -8.287 48.012 -1.477 1.00 39.77 ? 445 VAL A CG1 1 ATOM 3545 C CG2 . VAL A 1 441 ? -9.023 50.301 -2.080 1.00 39.36 ? 445 VAL A CG2 1 ATOM 3546 N N . LEU A 1 442 ? -6.517 46.927 -4.144 1.00 39.06 ? 446 LEU A N 1 ATOM 3547 C CA . LEU A 1 442 ? -6.096 45.579 -4.476 1.00 39.01 ? 446 LEU A CA 1 ATOM 3548 C C . LEU A 1 442 ? -5.883 44.754 -3.212 1.00 39.06 ? 446 LEU A C 1 ATOM 3549 O O . LEU A 1 442 ? -5.255 45.206 -2.261 1.00 38.84 ? 446 LEU A O 1 ATOM 3550 C CB . LEU A 1 442 ? -4.805 45.617 -5.296 1.00 39.11 ? 446 LEU A CB 1 ATOM 3551 C CG . LEU A 1 442 ? -4.269 44.308 -5.886 1.00 39.40 ? 446 LEU A CG 1 ATOM 3552 C CD1 . LEU A 1 442 ? -5.246 43.734 -6.908 1.00 40.03 ? 446 LEU A CD1 1 ATOM 3553 C CD2 . LEU A 1 442 ? -2.893 44.510 -6.503 1.00 38.59 ? 446 LEU A CD2 1 ATOM 3554 N N . MET A 1 443 ? -6.430 43.546 -3.220 1.00 39.28 ? 447 MET A N 1 ATOM 3555 C CA . MET A 1 443 ? -6.238 42.586 -2.150 1.00 39.54 ? 447 MET A CA 1 ATOM 3556 C C . MET A 1 443 ? -5.605 41.336 -2.745 1.00 39.91 ? 447 MET A C 1 ATOM 3557 O O . MET A 1 443 ? -6.094 40.793 -3.726 1.00 39.94 ? 447 MET A O 1 ATOM 3558 C CB . MET A 1 443 ? -7.567 42.246 -1.485 1.00 39.56 ? 447 MET A CB 1 ATOM 3559 C CG . MET A 1 443 ? -7.468 41.165 -0.431 1.00 39.63 ? 447 MET A CG 1 ATOM 3560 S SD . MET A 1 443 ? -9.060 40.733 0.291 1.00 39.15 ? 447 MET A SD 1 ATOM 3561 C CE . MET A 1 443 ? -8.614 39.219 1.109 1.00 39.77 ? 447 MET A CE 1 ATOM 3562 N N . CYS A 1 444 ? -4.498 40.910 -2.153 1.00 40.46 ? 448 CYS A N 1 ATOM 3563 C CA . CYS A 1 444 ? -3.741 39.768 -2.631 1.00 41.06 ? 448 CYS A CA 1 ATOM 3564 C C . CYS A 1 444 ? -3.629 38.768 -1.516 1.00 41.07 ? 448 CYS A C 1 ATOM 3565 O O . CYS A 1 444 ? -3.561 39.135 -0.342 1.00 41.19 ? 448 CYS A O 1 ATOM 3566 C CB . CYS A 1 444 ? -2.318 40.171 -3.044 1.00 41.13 ? 448 CYS A CB 1 ATOM 3567 S SG . CYS A 1 444 ? -2.200 41.443 -4.312 1.00 42.97 ? 448 CYS A SG 1 ATOM 3568 N N . SER A 1 445 ? -3.609 37.500 -1.891 1.00 41.28 ? 449 SER A N 1 ATOM 3569 C CA . SER A 1 445 ? -3.237 36.456 -0.973 1.00 41.61 ? 449 SER A CA 1 ATOM 3570 C C . SER A 1 445 ? -2.004 35.796 -1.588 1.00 42.08 ? 449 SER A C 1 ATOM 3571 O O . SER A 1 445 ? -2.105 35.085 -2.587 1.00 42.34 ? 449 SER A O 1 ATOM 3572 C CB . SER A 1 445 ? -4.391 35.481 -0.784 1.00 41.36 ? 449 SER A CB 1 ATOM 3573 O OG . SER A 1 445 ? -4.317 34.838 0.471 1.00 41.26 ? 449 SER A OG 1 ATOM 3574 N N . ASP A 1 446 ? -0.835 36.083 -1.019 1.00 42.42 ? 450 ASP A N 1 ATOM 3575 C CA . ASP A 1 446 ? 0.420 35.576 -1.549 1.00 42.84 ? 450 ASP A CA 1 ATOM 3576 C C . ASP A 1 446 ? 0.946 34.375 -0.752 1.00 42.92 ? 450 ASP A C 1 ATOM 3577 O O . ASP A 1 446 ? 1.284 34.480 0.438 1.00 42.54 ? 450 ASP A O 1 ATOM 3578 C CB . ASP A 1 446 ? 1.475 36.687 -1.637 1.00 42.85 ? 450 ASP A CB 1 ATOM 3579 C CG . ASP A 1 446 ? 2.730 36.247 -2.397 1.00 44.40 ? 450 ASP A CG 1 ATOM 3580 O OD1 . ASP A 1 446 ? 3.432 37.124 -2.952 1.00 46.01 ? 450 ASP A OD1 1 ATOM 3581 O OD2 . ASP A 1 446 ? 3.023 35.025 -2.443 1.00 45.42 ? 450 ASP A OD2 1 ATOM 3582 N N . GLN A 1 447 ? 1.019 33.237 -1.436 1.00 43.10 ? 451 GLN A N 1 ATOM 3583 C CA . GLN A 1 447 ? 1.530 32.007 -0.837 1.00 43.45 ? 451 GLN A CA 1 ATOM 3584 C C . GLN A 1 447 ? 2.743 31.429 -1.568 1.00 43.77 ? 451 GLN A C 1 ATOM 3585 O O . GLN A 1 447 ? 3.004 30.234 -1.512 1.00 43.77 ? 451 GLN A O 1 ATOM 3586 C CB . GLN A 1 447 ? 0.424 30.954 -0.642 1.00 43.26 ? 451 GLN A CB 1 ATOM 3587 C CG . GLN A 1 447 ? -0.684 30.934 -1.670 1.00 42.82 ? 451 GLN A CG 1 ATOM 3588 C CD . GLN A 1 447 ? -1.742 32.013 -1.446 1.00 42.35 ? 451 GLN A CD 1 ATOM 3589 O OE1 . GLN A 1 447 ? -1.975 32.475 -0.320 1.00 40.92 ? 451 GLN A OE1 1 ATOM 3590 N NE2 . GLN A 1 447 ? -2.389 32.418 -2.533 1.00 41.85 ? 451 GLN A NE2 1 ATOM 3591 N N . SER A 1 448 ? 3.497 32.298 -2.229 1.00 44.42 ? 452 SER A N 1 ATOM 3592 C CA . SER A 1 448 ? 4.738 31.898 -2.871 1.00 45.03 ? 452 SER A CA 1 ATOM 3593 C C . SER A 1 448 ? 5.796 31.490 -1.840 1.00 45.54 ? 452 SER A C 1 ATOM 3594 O O . SER A 1 448 ? 6.590 30.590 -2.089 1.00 45.45 ? 452 SER A O 1 ATOM 3595 C CB . SER A 1 448 ? 5.269 33.032 -3.745 1.00 44.85 ? 452 SER A CB 1 ATOM 3596 O OG . SER A 1 448 ? 5.617 34.144 -2.943 1.00 44.89 ? 452 SER A OG 1 ATOM 3597 N N . ARG A 1 449 ? 5.802 32.145 -0.686 1.00 46.33 ? 453 ARG A N 1 ATOM 3598 C CA . ARG A 1 449 ? 6.819 31.864 0.326 1.00 47.49 ? 453 ARG A CA 1 ATOM 3599 C C . ARG A 1 449 ? 6.201 31.242 1.574 1.00 47.09 ? 453 ARG A C 1 ATOM 3600 O O . ARG A 1 449 ? 6.788 31.273 2.655 1.00 47.11 ? 453 ARG A O 1 ATOM 3601 C CB . ARG A 1 449 ? 7.645 33.124 0.643 1.00 47.34 ? 453 ARG A CB 1 ATOM 3602 C CG . ARG A 1 449 ? 8.317 33.729 -0.616 1.00 49.10 ? 453 ARG A CG 1 ATOM 3603 C CD . ARG A 1 449 ? 9.578 34.554 -0.328 1.00 49.70 ? 453 ARG A CD 1 ATOM 3604 N NE . ARG A 1 449 ? 10.663 33.728 0.204 1.00 54.42 ? 453 ARG A NE 1 ATOM 3605 C CZ . ARG A 1 449 ? 10.981 33.642 1.500 1.00 56.49 ? 453 ARG A CZ 1 ATOM 3606 N NH1 . ARG A 1 449 ? 10.308 34.342 2.415 1.00 56.93 ? 453 ARG A NH1 1 ATOM 3607 N NH2 . ARG A 1 449 ? 11.977 32.852 1.890 1.00 57.16 ? 453 ARG A NH2 1 ATOM 3608 N N . SER A 1 450 ? 5.030 30.636 1.388 1.00 47.05 ? 454 SER A N 1 ATOM 3609 C CA . SER A 1 450 ? 4.217 30.100 2.482 1.00 46.90 ? 454 SER A CA 1 ATOM 3610 C C . SER A 1 450 ? 4.725 28.791 3.066 1.00 47.11 ? 454 SER A C 1 ATOM 3611 O O . SER A 1 450 ? 4.377 28.436 4.197 1.00 47.09 ? 454 SER A O 1 ATOM 3612 C CB . SER A 1 450 ? 2.795 29.886 1.991 1.00 46.75 ? 454 SER A CB 1 ATOM 3613 O OG . SER A 1 450 ? 2.774 28.906 0.973 1.00 45.84 ? 454 SER A OG 1 ATOM 3614 N N . SER A 1 451 ? 5.513 28.062 2.279 1.00 47.42 ? 455 SER A N 1 ATOM 3615 C CA . SER A 1 451 ? 6.036 26.761 2.681 1.00 47.70 ? 455 SER A CA 1 ATOM 3616 C C . SER A 1 451 ? 7.360 26.479 2.003 1.00 47.96 ? 455 SER A C 1 ATOM 3617 O O . SER A 1 451 ? 7.512 26.714 0.803 1.00 47.81 ? 455 SER A O 1 ATOM 3618 C CB . SER A 1 451 ? 5.048 25.644 2.335 1.00 47.83 ? 455 SER A CB 1 ATOM 3619 O OG . SER A 1 451 ? 5.602 24.362 2.608 1.00 47.91 ? 455 SER A OG 1 ATOM 3620 N N . LEU A 1 452 ? 8.307 25.955 2.776 1.00 48.29 ? 456 LEU A N 1 ATOM 3621 C CA . LEU A 1 452 ? 9.618 25.593 2.244 1.00 48.69 ? 456 LEU A CA 1 ATOM 3622 C C . LEU A 1 452 ? 9.572 24.421 1.253 1.00 49.26 ? 456 LEU A C 1 ATOM 3623 O O . LEU A 1 452 ? 10.449 24.324 0.393 1.00 49.75 ? 456 LEU A O 1 ATOM 3624 C CB . LEU A 1 452 ? 10.620 25.327 3.375 1.00 48.55 ? 456 LEU A CB 1 ATOM 3625 C CG . LEU A 1 452 ? 11.183 26.547 4.122 1.00 47.89 ? 456 LEU A CG 1 ATOM 3626 C CD1 . LEU A 1 452 ? 11.892 26.125 5.399 1.00 47.33 ? 456 LEU A CD1 1 ATOM 3627 C CD2 . LEU A 1 452 ? 12.113 27.375 3.246 1.00 46.87 ? 456 LEU A CD2 1 ATOM 3628 N N . LYS A 1 453 ? 8.561 23.549 1.359 1.00 49.54 ? 457 LYS A N 1 ATOM 3629 C CA . LYS A 1 453 ? 8.373 22.457 0.391 1.00 49.89 ? 457 LYS A CA 1 ATOM 3630 C C . LYS A 1 453 ? 7.821 22.973 -0.941 1.00 50.14 ? 457 LYS A C 1 ATOM 3631 O O . LYS A 1 453 ? 6.739 23.553 -0.980 1.00 50.28 ? 457 LYS A O 1 ATOM 3632 C CB . LYS A 1 453 ? 7.445 21.376 0.952 1.00 50.06 ? 457 LYS A CB 1 ATOM 3633 C CG . LYS A 1 453 ? 7.240 20.193 -0.001 1.00 50.22 ? 457 LYS A CG 1 ATOM 3634 C CD . LYS A 1 453 ? 6.264 19.148 0.536 1.00 50.10 ? 457 LYS A CD 1 ATOM 3635 C CE . LYS A 1 453 ? 6.584 17.777 -0.059 1.00 50.51 ? 457 LYS A CE 1 ATOM 3636 N NZ . LYS A 1 453 ? 5.381 16.945 -0.321 1.00 49.92 ? 457 LYS A NZ 1 ATOM 3637 N N . GLU A 1 454 ? 8.558 22.744 -2.026 1.00 50.56 ? 458 GLU A N 1 ATOM 3638 C CA . GLU A 1 454 ? 8.209 23.290 -3.348 1.00 51.07 ? 458 GLU A CA 1 ATOM 3639 C C . GLU A 1 454 ? 7.010 22.606 -4.002 1.00 50.61 ? 458 GLU A C 1 ATOM 3640 O O . GLU A 1 454 ? 6.301 23.232 -4.787 1.00 50.85 ? 458 GLU A O 1 ATOM 3641 C CB . GLU A 1 454 ? 9.408 23.230 -4.299 1.00 51.27 ? 458 GLU A CB 1 ATOM 3642 C CG . GLU A 1 454 ? 10.727 23.761 -3.718 1.00 52.39 ? 458 GLU A CG 1 ATOM 3643 C CD . GLU A 1 454 ? 11.711 24.235 -4.798 1.00 52.67 ? 458 GLU A CD 1 ATOM 3644 O OE1 . GLU A 1 454 ? 12.196 25.390 -4.673 1.00 55.23 ? 458 GLU A OE1 1 ATOM 3645 O OE2 . GLU A 1 454 ? 11.996 23.472 -5.762 1.00 52.97 ? 458 GLU A OE2 1 ATOM 3646 N N . ASP A 1 455 ? 6.807 21.325 -3.676 1.00 50.27 ? 459 ASP A N 1 ATOM 3647 C CA . ASP A 1 455 ? 5.683 20.482 -4.140 1.00 49.64 ? 459 ASP A CA 1 ATOM 3648 C C . ASP A 1 455 ? 4.269 21.066 -4.063 1.00 48.82 ? 459 ASP A C 1 ATOM 3649 O O . ASP A 1 455 ? 3.425 20.728 -4.883 1.00 49.01 ? 459 ASP A O 1 ATOM 3650 C CB . ASP A 1 455 ? 5.665 19.191 -3.337 1.00 50.11 ? 459 ASP A CB 1 ATOM 3651 C CG . ASP A 1 455 ? 6.488 18.108 -3.964 1.00 51.75 ? 459 ASP A CG 1 ATOM 3652 O OD1 . ASP A 1 455 ? 5.877 17.224 -4.607 1.00 54.02 ? 459 ASP A OD1 1 ATOM 3653 O OD2 . ASP A 1 455 ? 7.733 18.133 -3.816 1.00 52.93 ? 459 ASP A OD2 1 ATOM 3654 N N . ASN A 1 456 ? 3.998 21.891 -3.055 1.00 47.68 ? 460 ASN A N 1 ATOM 3655 C CA . ASN A 1 456 ? 2.692 22.531 -2.893 1.00 46.56 ? 460 ASN A CA 1 ATOM 3656 C C . ASN A 1 456 ? 2.349 23.501 -4.024 1.00 45.72 ? 460 ASN A C 1 ATOM 3657 O O . ASN A 1 456 ? 3.246 24.079 -4.628 1.00 45.88 ? 460 ASN A O 1 ATOM 3658 C CB . ASN A 1 456 ? 2.646 23.289 -1.567 1.00 46.67 ? 460 ASN A CB 1 ATOM 3659 C CG . ASN A 1 456 ? 2.991 22.417 -0.384 1.00 46.55 ? 460 ASN A CG 1 ATOM 3660 O OD1 . ASN A 1 456 ? 2.228 21.533 -0.006 1.00 46.98 ? 460 ASN A OD1 1 ATOM 3661 N ND2 . ASN A 1 456 ? 4.143 22.672 0.218 1.00 46.78 ? 460 ASN A ND2 1 ATOM 3662 N N . ASP A 1 457 ? 1.051 23.667 -4.293 1.00 44.65 ? 461 ASP A N 1 ATOM 3663 C CA . ASP A 1 457 ? 0.525 24.703 -5.189 1.00 43.54 ? 461 ASP A CA 1 ATOM 3664 C C . ASP A 1 457 ? 0.630 26.081 -4.538 1.00 42.84 ? 461 ASP A C 1 ATOM 3665 O O . ASP A 1 457 ? -0.153 26.431 -3.648 1.00 42.42 ? 461 ASP A O 1 ATOM 3666 C CB . ASP A 1 457 ? -0.937 24.417 -5.544 1.00 43.69 ? 461 ASP A CB 1 ATOM 3667 C CG . ASP A 1 457 ? -1.510 25.408 -6.560 1.00 44.75 ? 461 ASP A CG 1 ATOM 3668 O OD1 . ASP A 1 457 ? -0.805 26.372 -6.947 1.00 44.83 ? 461 ASP A OD1 1 ATOM 3669 O OD2 . ASP A 1 457 ? -2.678 25.215 -6.976 1.00 45.40 ? 461 ASP A OD2 1 ATOM 3670 N N . LYS A 1 458 ? 1.594 26.860 -5.016 1.00 42.01 ? 462 LYS A N 1 ATOM 3671 C CA . LYS A 1 458 ? 1.906 28.173 -4.465 1.00 41.42 ? 462 LYS A CA 1 ATOM 3672 C C . LYS A 1 458 ? 1.274 29.332 -5.244 1.00 40.02 ? 462 LYS A C 1 ATOM 3673 O O . LYS A 1 458 ? 1.694 30.472 -5.110 1.00 40.08 ? 462 LYS A O 1 ATOM 3674 C CB . LYS A 1 458 ? 3.426 28.343 -4.382 1.00 41.57 ? 462 LYS A CB 1 ATOM 3675 C CG . LYS A 1 458 ? 4.081 27.449 -3.320 1.00 42.83 ? 462 LYS A CG 1 ATOM 3676 C CD . LYS A 1 458 ? 5.581 27.693 -3.252 1.00 42.79 ? 462 LYS A CD 1 ATOM 3677 C CE . LYS A 1 458 ? 6.196 26.921 -2.104 1.00 45.13 ? 462 LYS A CE 1 ATOM 3678 N NZ . LYS A 1 458 ? 7.359 27.657 -1.513 1.00 45.81 ? 462 LYS A NZ 1 ATOM 3679 N N . THR A 1 459 ? 0.256 29.032 -6.044 1.00 38.54 ? 463 THR A N 1 ATOM 3680 C CA . THR A 1 459 ? -0.467 30.046 -6.804 1.00 37.06 ? 463 THR A CA 1 ATOM 3681 C C . THR A 1 459 ? -0.972 31.189 -5.914 1.00 36.49 ? 463 THR A C 1 ATOM 3682 O O . THR A 1 459 ? -1.580 30.962 -4.850 1.00 36.42 ? 463 THR A O 1 ATOM 3683 C CB . THR A 1 459 ? -1.637 29.404 -7.594 1.00 37.00 ? 463 THR A CB 1 ATOM 3684 O OG1 . THR A 1 459 ? -1.113 28.384 -8.451 1.00 37.03 ? 463 THR A OG1 1 ATOM 3685 C CG2 . THR A 1 459 ? -2.380 30.425 -8.442 1.00 35.50 ? 463 THR A CG2 1 ATOM 3686 N N . THR A 1 460 ? -0.700 32.413 -6.356 1.00 35.36 ? 464 THR A N 1 ATOM 3687 C CA . THR A 1 460 ? -1.145 33.614 -5.666 1.00 34.70 ? 464 THR A CA 1 ATOM 3688 C C . THR A 1 460 ? -2.516 34.042 -6.163 1.00 34.23 ? 464 THR A C 1 ATOM 3689 O O . THR A 1 460 ? -2.807 33.945 -7.356 1.00 34.19 ? 464 THR A O 1 ATOM 3690 C CB . THR A 1 460 ? -0.129 34.757 -5.847 1.00 34.77 ? 464 THR A CB 1 ATOM 3691 O OG1 . THR A 1 460 ? 1.067 34.437 -5.122 1.00 35.30 ? 464 THR A OG1 1 ATOM 3692 C CG2 . THR A 1 460 ? -0.687 36.077 -5.342 1.00 34.24 ? 464 THR A CG2 1 ATOM 3693 N N . TYR A 1 461 ? -3.354 34.510 -5.239 1.00 33.89 ? 465 TYR A N 1 ATOM 3694 C CA . TYR A 1 461 ? -4.720 34.943 -5.563 1.00 33.19 ? 465 TYR A CA 1 ATOM 3695 C C . TYR A 1 461 ? -4.875 36.444 -5.404 1.00 32.91 ? 465 TYR A C 1 ATOM 3696 O O . TYR A 1 461 ? -4.188 37.063 -4.587 1.00 32.69 ? 465 TYR A O 1 ATOM 3697 C CB . TYR A 1 461 ? -5.741 34.214 -4.697 1.00 32.46 ? 465 TYR A CB 1 ATOM 3698 C CG . TYR A 1 461 ? -5.546 32.721 -4.670 1.00 32.33 ? 465 TYR A CG 1 ATOM 3699 C CD1 . TYR A 1 461 ? -5.533 31.975 -5.841 1.00 30.88 ? 465 TYR A CD1 1 ATOM 3700 C CD2 . TYR A 1 461 ? -5.371 32.044 -3.461 1.00 32.73 ? 465 TYR A CD2 1 ATOM 3701 C CE1 . TYR A 1 461 ? -5.342 30.597 -5.809 1.00 30.76 ? 465 TYR A CE1 1 ATOM 3702 C CE2 . TYR A 1 461 ? -5.187 30.668 -3.423 1.00 31.01 ? 465 TYR A CE2 1 ATOM 3703 C CZ . TYR A 1 461 ? -5.172 29.957 -4.597 1.00 31.38 ? 465 TYR A CZ 1 ATOM 3704 O OH . TYR A 1 461 ? -5.008 28.593 -4.551 1.00 32.76 ? 465 TYR A OH 1 ATOM 3705 N N . GLY A 1 462 ? -5.781 37.014 -6.195 1.00 32.74 ? 466 GLY A N 1 ATOM 3706 C CA . GLY A 1 462 ? -6.035 38.450 -6.181 1.00 32.43 ? 466 GLY A CA 1 ATOM 3707 C C . GLY A 1 462 ? -7.482 38.822 -6.437 1.00 32.35 ? 466 GLY A C 1 ATOM 3708 O O . GLY A 1 462 ? -8.197 38.139 -7.179 1.00 32.22 ? 466 GLY A O 1 ATOM 3709 N N . ALA A 1 463 ? -7.900 39.925 -5.818 1.00 32.50 ? 467 ALA A N 1 ATOM 3710 C CA . ALA A 1 463 ? -9.240 40.479 -5.979 1.00 32.46 ? 467 ALA A CA 1 ATOM 3711 C C . ALA A 1 463 ? -9.227 42.002 -5.843 1.00 32.52 ? 467 ALA A C 1 ATOM 3712 O O . ALA A 1 463 ? -8.376 42.563 -5.146 1.00 32.52 ? 467 ALA A O 1 ATOM 3713 C CB . ALA A 1 463 ? -10.183 39.871 -4.959 1.00 32.32 ? 467 ALA A CB 1 ATOM 3714 N N . PHE A 1 464 ? -10.163 42.659 -6.527 1.00 32.54 ? 468 PHE A N 1 ATOM 3715 C CA . PHE A 1 464 ? -10.431 44.080 -6.316 1.00 32.44 ? 468 PHE A CA 1 ATOM 3716 C C . PHE A 1 464 ? -11.473 44.234 -5.222 1.00 33.15 ? 468 PHE A C 1 ATOM 3717 O O . PHE A 1 464 ? -12.338 43.382 -5.052 1.00 33.39 ? 468 PHE A O 1 ATOM 3718 C CB . PHE A 1 464 ? -10.927 44.752 -7.599 1.00 31.75 ? 468 PHE A CB 1 ATOM 3719 C CG . PHE A 1 464 ? -9.875 44.896 -8.652 1.00 30.50 ? 468 PHE A CG 1 ATOM 3720 C CD1 . PHE A 1 464 ? -10.069 44.362 -9.914 1.00 28.93 ? 468 PHE A CD1 1 ATOM 3721 C CD2 . PHE A 1 464 ? -8.678 45.559 -8.377 1.00 30.06 ? 468 PHE A CD2 1 ATOM 3722 C CE1 . PHE A 1 464 ? -9.097 44.483 -10.893 1.00 28.81 ? 468 PHE A CE1 1 ATOM 3723 C CE2 . PHE A 1 464 ? -7.691 45.688 -9.353 1.00 29.33 ? 468 PHE A CE2 1 ATOM 3724 C CZ . PHE A 1 464 ? -7.902 45.147 -10.614 1.00 29.82 ? 468 PHE A CZ 1 ATOM 3725 N N . VAL A 1 465 ? -11.384 45.319 -4.468 1.00 33.96 ? 469 VAL A N 1 ATOM 3726 C CA . VAL A 1 465 ? -12.303 45.555 -3.367 1.00 34.41 ? 469 VAL A CA 1 ATOM 3727 C C . VAL A 1 465 ? -13.015 46.883 -3.618 1.00 35.21 ? 469 VAL A C 1 ATOM 3728 O O . VAL A 1 465 ? -12.376 47.914 -3.834 1.00 35.24 ? 469 VAL A O 1 ATOM 3729 C CB . VAL A 1 465 ? -11.562 45.598 -2.012 1.00 34.38 ? 469 VAL A CB 1 ATOM 3730 C CG1 . VAL A 1 465 ? -12.538 45.397 -0.870 1.00 34.41 ? 469 VAL A CG1 1 ATOM 3731 C CG2 . VAL A 1 465 ? -10.440 44.544 -1.954 1.00 33.61 ? 469 VAL A CG2 1 ATOM 3732 N N . ASP A 1 466 ? -14.340 46.847 -3.615 1.00 35.83 ? 470 ASP A N 1 ATOM 3733 C CA . ASP A 1 466 ? -15.121 48.049 -3.809 1.00 36.26 ? 470 ASP A CA 1 ATOM 3734 C C . ASP A 1 466 ? -15.330 48.735 -2.461 1.00 36.62 ? 470 ASP A C 1 ATOM 3735 O O . ASP A 1 466 ? -16.414 48.676 -1.860 1.00 36.85 ? 470 ASP A O 1 ATOM 3736 C CB . ASP A 1 466 ? -16.452 47.712 -4.486 1.00 36.53 ? 470 ASP A CB 1 ATOM 3737 C CG . ASP A 1 466 ? -17.276 48.943 -4.818 1.00 37.78 ? 470 ASP A CG 1 ATOM 3738 O OD1 . ASP A 1 466 ? -16.711 50.064 -4.804 1.00 39.51 ? 470 ASP A OD1 1 ATOM 3739 O OD2 . ASP A 1 466 ? -18.489 48.787 -5.099 1.00 38.76 ? 470 ASP A OD2 1 ATOM 3740 N N . ILE A 1 467 ? -14.270 49.368 -1.976 1.00 36.71 ? 471 ILE A N 1 ATOM 3741 C CA . ILE A 1 467 ? -14.364 50.229 -0.808 1.00 36.84 ? 471 ILE A CA 1 ATOM 3742 C C . ILE A 1 467 ? -13.604 51.530 -1.051 1.00 37.41 ? 471 ILE A C 1 ATOM 3743 O O . ILE A 1 467 ? -12.720 51.589 -1.915 1.00 37.43 ? 471 ILE A O 1 ATOM 3744 C CB . ILE A 1 467 ? -13.865 49.535 0.486 1.00 36.85 ? 471 ILE A CB 1 ATOM 3745 C CG1 . ILE A 1 467 ? -12.444 48.982 0.311 1.00 36.45 ? 471 ILE A CG1 1 ATOM 3746 C CG2 . ILE A 1 467 ? -14.857 48.471 0.927 1.00 36.54 ? 471 ILE A CG2 1 ATOM 3747 C CD1 . ILE A 1 467 ? -11.887 48.302 1.536 1.00 36.37 ? 471 ILE A CD1 1 ATOM 3748 N N . ASN A 1 468 ? -13.958 52.561 -0.283 1.00 37.77 ? 472 ASN A N 1 ATOM 3749 C CA . ASN A 1 468 ? -13.353 53.882 -0.391 1.00 38.11 ? 472 ASN A CA 1 ATOM 3750 C C . ASN A 1 468 ? -12.183 54.028 0.579 1.00 38.41 ? 472 ASN A C 1 ATOM 3751 O O . ASN A 1 468 ? -12.379 54.033 1.789 1.00 38.57 ? 472 ASN A O 1 ATOM 3752 C CB . ASN A 1 468 ? -14.412 54.952 -0.110 1.00 38.33 ? 472 ASN A CB 1 ATOM 3753 C CG . ASN A 1 468 ? -13.974 56.346 -0.532 1.00 38.98 ? 472 ASN A CG 1 ATOM 3754 O OD1 . ASN A 1 468 ? -12.789 56.676 -0.527 1.00 40.13 ? 472 ASN A OD1 1 ATOM 3755 N ND2 . ASN A 1 468 ? -14.939 57.171 -0.899 1.00 39.77 ? 472 ASN A ND2 1 ATOM 3756 N N . PRO A 1 469 ? -10.955 54.158 0.057 1.00 38.81 ? 473 PRO A N 1 ATOM 3757 C CA . PRO A 1 469 ? -9.793 54.197 0.954 1.00 39.13 ? 473 PRO A CA 1 ATOM 3758 C C . PRO A 1 469 ? -9.614 55.509 1.739 1.00 39.73 ? 473 PRO A C 1 ATOM 3759 O O . PRO A 1 469 ? -8.642 55.651 2.487 1.00 39.83 ? 473 PRO A O 1 ATOM 3760 C CB . PRO A 1 469 ? -8.617 53.955 0.011 1.00 39.16 ? 473 PRO A CB 1 ATOM 3761 C CG . PRO A 1 469 ? -9.087 54.434 -1.322 1.00 38.88 ? 473 PRO A CG 1 ATOM 3762 C CD . PRO A 1 469 ? -10.576 54.257 -1.365 1.00 38.72 ? 473 PRO A CD 1 ATOM 3763 N N . HIS A 1 470 ? -10.530 56.460 1.558 1.00 40.39 ? 474 HIS A N 1 ATOM 3764 C CA . HIS A 1 470 ? -10.619 57.616 2.448 1.00 40.85 ? 474 HIS A CA 1 ATOM 3765 C C . HIS A 1 470 ? -10.967 57.084 3.826 1.00 41.17 ? 474 HIS A C 1 ATOM 3766 O O . HIS A 1 470 ? -10.386 57.513 4.816 1.00 41.56 ? 474 HIS A O 1 ATOM 3767 C CB . HIS A 1 470 ? -11.687 58.610 1.978 1.00 40.84 ? 474 HIS A CB 1 ATOM 3768 C CG . HIS A 1 470 ? -11.242 59.493 0.853 1.00 41.04 ? 474 HIS A CG 1 ATOM 3769 N ND1 . HIS A 1 470 ? -11.376 59.139 -0.473 1.00 41.57 ? 474 HIS A ND1 1 ATOM 3770 C CD2 . HIS A 1 470 ? -10.667 60.718 0.856 1.00 41.12 ? 474 HIS A CD2 1 ATOM 3771 C CE1 . HIS A 1 470 ? -10.907 60.107 -1.238 1.00 40.73 ? 474 HIS A CE1 1 ATOM 3772 N NE2 . HIS A 1 470 ? -10.468 61.076 -0.456 1.00 41.92 ? 474 HIS A NE2 1 ATOM 3773 N N . GLN A 1 471 ? -11.906 56.136 3.864 1.00 41.49 ? 475 GLN A N 1 ATOM 3774 C CA . GLN A 1 471 ? -12.259 55.372 5.067 1.00 41.77 ? 475 GLN A CA 1 ATOM 3775 C C . GLN A 1 471 ? -11.157 54.375 5.446 1.00 41.34 ? 475 GLN A C 1 ATOM 3776 O O . GLN A 1 471 ? -10.292 54.067 4.630 1.00 41.40 ? 475 GLN A O 1 ATOM 3777 C CB . GLN A 1 471 ? -13.573 54.618 4.827 1.00 42.10 ? 475 GLN A CB 1 ATOM 3778 C CG . GLN A 1 471 ? -14.792 55.216 5.498 1.00 44.27 ? 475 GLN A CG 1 ATOM 3779 C CD . GLN A 1 471 ? -14.916 56.712 5.273 1.00 46.78 ? 475 GLN A CD 1 ATOM 3780 O OE1 . GLN A 1 471 ? -14.713 57.498 6.200 1.00 47.01 ? 475 GLN A OE1 1 ATOM 3781 N NE2 . GLN A 1 471 ? -15.236 57.115 4.035 1.00 46.66 ? 475 GLN A NE2 1 ATOM 3782 N N . PRO A 1 472 ? -11.187 53.853 6.685 1.00 41.09 ? 476 PRO A N 1 ATOM 3783 C CA . PRO A 1 472 ? -10.160 52.860 7.037 1.00 40.76 ? 476 PRO A CA 1 ATOM 3784 C C . PRO A 1 472 ? -10.385 51.487 6.360 1.00 40.44 ? 476 PRO A C 1 ATOM 3785 O O . PRO A 1 472 ? -11.533 51.034 6.216 1.00 40.30 ? 476 PRO A O 1 ATOM 3786 C CB . PRO A 1 472 ? -10.280 52.743 8.564 1.00 40.84 ? 476 PRO A CB 1 ATOM 3787 C CG . PRO A 1 472 ? -11.337 53.738 8.988 1.00 40.90 ? 476 PRO A CG 1 ATOM 3788 C CD . PRO A 1 472 ? -12.126 54.107 7.792 1.00 40.78 ? 476 PRO A CD 1 ATOM 3789 N N . LEU A 1 473 ? -9.290 50.840 5.957 1.00 39.95 ? 477 LEU A N 1 ATOM 3790 C CA . LEU A 1 473 ? -9.341 49.558 5.240 1.00 39.09 ? 477 LEU A CA 1 ATOM 3791 C C . LEU A 1 473 ? -9.415 48.387 6.191 1.00 38.55 ? 477 LEU A C 1 ATOM 3792 O O . LEU A 1 473 ? -8.547 48.202 7.057 1.00 38.45 ? 477 LEU A O 1 ATOM 3793 C CB . LEU A 1 473 ? -8.131 49.383 4.337 1.00 39.15 ? 477 LEU A CB 1 ATOM 3794 C CG . LEU A 1 473 ? -8.057 50.149 3.021 1.00 39.40 ? 477 LEU A CG 1 ATOM 3795 C CD1 . LEU A 1 473 ? -7.852 51.637 3.253 1.00 39.16 ? 477 LEU A CD1 1 ATOM 3796 C CD2 . LEU A 1 473 ? -6.893 49.578 2.234 1.00 39.73 ? 477 LEU A CD2 1 ATOM 3797 N N . SER A 1 474 ? -10.457 47.587 6.004 1.00 37.89 ? 478 SER A N 1 ATOM 3798 C CA . SER A 1 474 ? -10.779 46.502 6.912 1.00 37.13 ? 478 SER A CA 1 ATOM 3799 C C . SER A 1 474 ? -10.273 45.165 6.373 1.00 36.68 ? 478 SER A C 1 ATOM 3800 O O . SER A 1 474 ? -10.468 44.854 5.202 1.00 37.00 ? 478 SER A O 1 ATOM 3801 C CB . SER A 1 474 ? -12.286 46.475 7.149 1.00 36.82 ? 478 SER A CB 1 ATOM 3802 O OG . SER A 1 474 ? -12.681 45.236 7.687 1.00 37.78 ? 478 SER A OG 1 ATOM 3803 N N . LEU A 1 475 ? -9.600 44.392 7.223 1.00 36.09 ? 479 LEU A N 1 ATOM 3804 C CA . LEU A 1 475 ? -9.130 43.053 6.851 1.00 35.69 ? 479 LEU A CA 1 ATOM 3805 C C . LEU A 1 475 ? -9.352 42.053 7.982 1.00 35.48 ? 479 LEU A C 1 ATOM 3806 O O . LEU A 1 475 ? -8.979 42.300 9.123 1.00 35.51 ? 479 LEU A O 1 ATOM 3807 C CB . LEU A 1 475 ? -7.650 43.068 6.418 1.00 35.63 ? 479 LEU A CB 1 ATOM 3808 C CG . LEU A 1 475 ? -6.938 41.769 5.986 1.00 35.59 ? 479 LEU A CG 1 ATOM 3809 C CD1 . LEU A 1 475 ? -7.671 41.003 4.892 1.00 35.30 ? 479 LEU A CD1 1 ATOM 3810 C CD2 . LEU A 1 475 ? -5.528 42.050 5.533 1.00 35.27 ? 479 LEU A CD2 1 ATOM 3811 N N . ARG A 1 476 ? -9.979 40.930 7.650 1.00 35.28 ? 480 ARG A N 1 ATOM 3812 C CA . ARG A 1 476 ? -10.125 39.817 8.579 1.00 34.87 ? 480 ARG A CA 1 ATOM 3813 C C . ARG A 1 476 ? -9.475 38.567 7.992 1.00 34.75 ? 480 ARG A C 1 ATOM 3814 O O . ARG A 1 476 ? -9.433 38.391 6.771 1.00 34.90 ? 480 ARG A O 1 ATOM 3815 C CB . ARG A 1 476 ? -11.597 39.557 8.888 1.00 34.75 ? 480 ARG A CB 1 ATOM 3816 C CG . ARG A 1 476 ? -11.847 38.406 9.844 1.00 34.40 ? 480 ARG A CG 1 ATOM 3817 C CD . ARG A 1 476 ? -13.332 38.186 10.041 1.00 34.72 ? 480 ARG A CD 1 ATOM 3818 N NE . ARG A 1 476 ? -13.600 37.126 11.006 1.00 35.36 ? 480 ARG A NE 1 ATOM 3819 C CZ . ARG A 1 476 ? -14.808 36.667 11.304 1.00 35.50 ? 480 ARG A CZ 1 ATOM 3820 N NH1 . ARG A 1 476 ? -15.882 37.162 10.713 1.00 36.29 ? 480 ARG A NH1 1 ATOM 3821 N NH2 . ARG A 1 476 ? -14.941 35.699 12.188 1.00 36.42 ? 480 ARG A NH2 1 ATOM 3822 N N . ALA A 1 477 ? -8.971 37.711 8.877 1.00 34.42 ? 481 ALA A N 1 ATOM 3823 C CA . ALA A 1 477 ? -8.346 36.454 8.502 1.00 33.85 ? 481 ALA A CA 1 ATOM 3824 C C . ALA A 1 477 ? -8.653 35.379 9.546 1.00 33.62 ? 481 ALA A C 1 ATOM 3825 O O . ALA A 1 477 ? -8.385 35.573 10.736 1.00 33.33 ? 481 ALA A O 1 ATOM 3826 C CB . ALA A 1 477 ? -6.854 36.647 8.370 1.00 33.80 ? 481 ALA A CB 1 ATOM 3827 N N . LEU A 1 478 ? -9.245 34.270 9.097 1.00 33.34 ? 482 LEU A N 1 ATOM 3828 C CA . LEU A 1 478 ? -9.389 33.062 9.915 1.00 32.97 ? 482 LEU A CA 1 ATOM 3829 C C . LEU A 1 478 ? -8.234 32.152 9.568 1.00 33.06 ? 482 LEU A C 1 ATOM 3830 O O . LEU A 1 478 ? -8.074 31.755 8.409 1.00 33.15 ? 482 LEU A O 1 ATOM 3831 C CB . LEU A 1 478 ? -10.710 32.342 9.638 1.00 32.84 ? 482 LEU A CB 1 ATOM 3832 C CG . LEU A 1 478 ? -12.006 32.941 10.188 1.00 32.58 ? 482 LEU A CG 1 ATOM 3833 C CD1 . LEU A 1 478 ? -13.188 32.653 9.266 1.00 31.22 ? 482 LEU A CD1 1 ATOM 3834 C CD2 . LEU A 1 478 ? -12.263 32.421 11.581 1.00 32.43 ? 482 LEU A CD2 1 ATOM 3835 N N . ILE A 1 479 ? -7.422 31.837 10.570 1.00 33.17 ? 483 ILE A N 1 ATOM 3836 C CA . ILE A 1 479 ? -6.180 31.103 10.372 1.00 33.32 ? 483 ILE A CA 1 ATOM 3837 C C . ILE A 1 479 ? -6.364 29.734 10.996 1.00 33.60 ? 483 ILE A C 1 ATOM 3838 O O . ILE A 1 479 ? -6.676 29.656 12.180 1.00 34.07 ? 483 ILE A O 1 ATOM 3839 C CB . ILE A 1 479 ? -5.001 31.862 11.036 1.00 33.33 ? 483 ILE A CB 1 ATOM 3840 C CG1 . ILE A 1 479 ? -4.981 33.324 10.580 1.00 32.99 ? 483 ILE A CG1 1 ATOM 3841 C CG2 . ILE A 1 479 ? -3.667 31.213 10.702 1.00 34.00 ? 483 ILE A CG2 1 ATOM 3842 C CD1 . ILE A 1 479 ? -3.921 34.161 11.243 1.00 33.05 ? 483 ILE A CD1 1 ATOM 3843 N N . ASP A 1 480 ? -6.198 28.659 10.217 1.00 33.91 ? 484 ASP A N 1 ATOM 3844 C CA . ASP A 1 480 ? -6.499 27.295 10.720 1.00 34.26 ? 484 ASP A CA 1 ATOM 3845 C C . ASP A 1 480 ? -5.576 26.191 10.179 1.00 34.34 ? 484 ASP A C 1 ATOM 3846 O O . ASP A 1 480 ? -5.988 25.320 9.411 1.00 34.21 ? 484 ASP A O 1 ATOM 3847 C CB . ASP A 1 480 ? -7.982 26.941 10.507 1.00 34.18 ? 484 ASP A CB 1 ATOM 3848 C CG . ASP A 1 480 ? -8.463 25.807 11.418 1.00 35.36 ? 484 ASP A CG 1 ATOM 3849 O OD1 . ASP A 1 480 ? -9.656 25.416 11.317 1.00 36.21 ? 484 ASP A OD1 1 ATOM 3850 O OD2 . ASP A 1 480 ? -7.661 25.304 12.240 1.00 35.74 ? 484 ASP A OD2 1 ATOM 3851 N N . HIS A 1 481 ? -4.324 26.243 10.617 1.00 34.78 ? 485 HIS A N 1 ATOM 3852 C CA . HIS A 1 481 ? -3.272 25.274 10.269 1.00 35.10 ? 485 HIS A CA 1 ATOM 3853 C C . HIS A 1 481 ? -2.864 25.213 8.801 1.00 34.86 ? 485 HIS A C 1 ATOM 3854 O O . HIS A 1 481 ? -1.732 25.579 8.481 1.00 35.09 ? 485 HIS A O 1 ATOM 3855 C CB . HIS A 1 481 ? -3.546 23.896 10.878 1.00 35.61 ? 485 HIS A CB 1 ATOM 3856 C CG . HIS A 1 481 ? -3.655 23.939 12.365 1.00 36.92 ? 485 HIS A CG 1 ATOM 3857 N ND1 . HIS A 1 481 ? -2.550 23.942 13.188 1.00 39.25 ? 485 HIS A ND1 1 ATOM 3858 C CD2 . HIS A 1 481 ? -4.732 24.062 13.176 1.00 37.67 ? 485 HIS A CD2 1 ATOM 3859 C CE1 . HIS A 1 481 ? -2.942 24.036 14.447 1.00 38.81 ? 485 HIS A CE1 1 ATOM 3860 N NE2 . HIS A 1 481 ? -4.261 24.110 14.466 1.00 38.90 ? 485 HIS A NE2 1 ATOM 3861 N N . SER A 1 482 ? -3.754 24.767 7.917 1.00 34.48 ? 486 SER A N 1 ATOM 3862 C CA . SER A 1 482 ? -3.415 24.712 6.489 1.00 34.28 ? 486 SER A CA 1 ATOM 3863 C C . SER A 1 482 ? -4.420 25.437 5.595 1.00 34.53 ? 486 SER A C 1 ATOM 3864 O O . SER A 1 482 ? -4.445 25.238 4.374 1.00 34.49 ? 486 SER A O 1 ATOM 3865 C CB . SER A 1 482 ? -3.211 23.269 6.022 1.00 34.16 ? 486 SER A CB 1 ATOM 3866 O OG . SER A 1 482 ? -4.416 22.526 6.085 1.00 34.00 ? 486 SER A OG 1 ATOM 3867 N N . VAL A 1 483 ? -5.250 26.274 6.210 1.00 34.60 ? 487 VAL A N 1 ATOM 3868 C CA . VAL A 1 483 ? -6.202 27.086 5.466 1.00 34.86 ? 487 VAL A CA 1 ATOM 3869 C C . VAL A 1 483 ? -6.245 28.500 6.029 1.00 34.90 ? 487 VAL A C 1 ATOM 3870 O O . VAL A 1 483 ? -6.235 28.685 7.244 1.00 35.58 ? 487 VAL A O 1 ATOM 3871 C CB . VAL A 1 483 ? -7.616 26.454 5.459 1.00 34.99 ? 487 VAL A CB 1 ATOM 3872 C CG1 . VAL A 1 483 ? -8.125 26.214 6.876 1.00 35.13 ? 487 VAL A CG1 1 ATOM 3873 C CG2 . VAL A 1 483 ? -8.595 27.324 4.676 1.00 34.94 ? 487 VAL A CG2 1 ATOM 3874 N N . VAL A 1 484 ? -6.269 29.488 5.138 1.00 34.65 ? 488 VAL A N 1 ATOM 3875 C CA . VAL A 1 484 ? -6.439 30.888 5.511 1.00 34.19 ? 488 VAL A CA 1 ATOM 3876 C C . VAL A 1 484 ? -7.652 31.379 4.754 1.00 33.74 ? 488 VAL A C 1 ATOM 3877 O O . VAL A 1 484 ? -7.760 31.163 3.544 1.00 33.45 ? 488 VAL A O 1 ATOM 3878 C CB . VAL A 1 484 ? -5.201 31.762 5.114 1.00 34.65 ? 488 VAL A CB 1 ATOM 3879 C CG1 . VAL A 1 484 ? -5.330 33.190 5.654 1.00 34.33 ? 488 VAL A CG1 1 ATOM 3880 C CG2 . VAL A 1 484 ? -3.889 31.125 5.593 1.00 34.85 ? 488 VAL A CG2 1 ATOM 3881 N N . GLU A 1 485 ? -8.575 32.009 5.471 1.00 33.51 ? 489 GLU A N 1 ATOM 3882 C CA . GLU A 1 485 ? -9.754 32.629 4.865 1.00 33.49 ? 489 GLU A CA 1 ATOM 3883 C C . GLU A 1 485 ? -9.708 34.145 5.081 1.00 33.53 ? 489 GLU A C 1 ATOM 3884 O O . GLU A 1 485 ? -9.930 34.649 6.201 1.00 33.44 ? 489 GLU A O 1 ATOM 3885 C CB . GLU A 1 485 ? -11.047 32.027 5.419 1.00 33.04 ? 489 GLU A CB 1 ATOM 3886 C CG . GLU A 1 485 ? -11.354 30.624 4.924 1.00 33.16 ? 489 GLU A CG 1 ATOM 3887 C CD . GLU A 1 485 ? -12.740 30.148 5.343 1.00 34.36 ? 489 GLU A CD 1 ATOM 3888 O OE1 . GLU A 1 485 ? -13.738 30.698 4.834 1.00 36.43 ? 489 GLU A OE1 1 ATOM 3889 O OE2 . GLU A 1 485 ? -12.850 29.221 6.177 1.00 35.34 ? 489 GLU A OE2 1 ATOM 3890 N N . SER A 1 486 ? -9.401 34.869 4.007 1.00 33.48 ? 490 SER A N 1 ATOM 3891 C CA . SER A 1 486 ? -9.198 36.311 4.093 1.00 33.61 ? 490 SER A CA 1 ATOM 3892 C C . SER A 1 486 ? -10.397 37.095 3.582 1.00 33.68 ? 490 SER A C 1 ATOM 3893 O O . SER A 1 486 ? -10.944 36.796 2.512 1.00 33.74 ? 490 SER A O 1 ATOM 3894 C CB . SER A 1 486 ? -7.940 36.715 3.339 1.00 33.57 ? 490 SER A CB 1 ATOM 3895 O OG . SER A 1 486 ? -6.844 35.882 3.691 1.00 34.80 ? 490 SER A OG 1 ATOM 3896 N N . PHE A 1 487 ? -10.807 38.090 4.371 1.00 33.68 ? 491 PHE A N 1 ATOM 3897 C CA . PHE A 1 487 ? -11.918 38.983 4.020 1.00 33.18 ? 491 PHE A CA 1 ATOM 3898 C C . PHE A 1 487 ? -11.475 40.446 4.087 1.00 32.98 ? 491 PHE A C 1 ATOM 3899 O O . PHE A 1 487 ? -11.127 40.967 5.156 1.00 32.72 ? 491 PHE A O 1 ATOM 3900 C CB . PHE A 1 487 ? -13.128 38.752 4.938 1.00 33.05 ? 491 PHE A CB 1 ATOM 3901 C CG . PHE A 1 487 ? -13.562 37.317 5.031 1.00 32.48 ? 491 PHE A CG 1 ATOM 3902 C CD1 . PHE A 1 487 ? -14.639 36.862 4.298 1.00 32.16 ? 491 PHE A CD1 1 ATOM 3903 C CD2 . PHE A 1 487 ? -12.900 36.424 5.866 1.00 32.75 ? 491 PHE A CD2 1 ATOM 3904 C CE1 . PHE A 1 487 ? -15.048 35.538 4.384 1.00 32.06 ? 491 PHE A CE1 1 ATOM 3905 C CE2 . PHE A 1 487 ? -13.305 35.092 5.955 1.00 32.51 ? 491 PHE A CE2 1 ATOM 3906 C CZ . PHE A 1 487 ? -14.378 34.653 5.209 1.00 32.17 ? 491 PHE A CZ 1 ATOM 3907 N N . GLY A 1 488 ? -11.466 41.090 2.927 1.00 32.84 ? 492 GLY A N 1 ATOM 3908 C CA . GLY A 1 488 ? -11.195 42.517 2.840 1.00 32.95 ? 492 GLY A CA 1 ATOM 3909 C C . GLY A 1 488 ? -12.509 43.248 2.696 1.00 33.13 ? 492 GLY A C 1 ATOM 3910 O O . GLY A 1 488 ? -13.491 42.674 2.227 1.00 33.45 ? 492 GLY A O 1 ATOM 3911 N N . GLY A 1 489 ? -12.536 44.507 3.116 1.00 33.16 ? 493 GLY A N 1 ATOM 3912 C CA . GLY A 1 489 ? -13.732 45.340 3.001 1.00 33.23 ? 493 GLY A CA 1 ATOM 3913 C C . GLY A 1 489 ? -14.983 44.793 3.675 1.00 33.18 ? 493 GLY A C 1 ATOM 3914 O O . GLY A 1 489 ? -16.085 44.903 3.123 1.00 33.31 ? 493 GLY A O 1 ATOM 3915 N N . LYS A 1 490 ? -14.812 44.228 4.871 1.00 32.84 ? 494 LYS A N 1 ATOM 3916 C CA . LYS A 1 490 ? -15.901 43.615 5.635 1.00 32.70 ? 494 LYS A CA 1 ATOM 3917 C C . LYS A 1 490 ? -16.739 42.675 4.773 1.00 32.41 ? 494 LYS A C 1 ATOM 3918 O O . LYS A 1 490 ? -17.963 42.748 4.761 1.00 32.37 ? 494 LYS A O 1 ATOM 3919 C CB . LYS A 1 490 ? -16.800 44.657 6.317 1.00 32.46 ? 494 LYS A CB 1 ATOM 3920 C CG . LYS A 1 490 ? -16.122 45.649 7.286 1.00 34.49 ? 494 LYS A CG 1 ATOM 3921 C CD . LYS A 1 490 ? -15.491 45.071 8.603 1.00 37.93 ? 494 LYS A CD 1 ATOM 3922 C CE . LYS A 1 490 ? -16.319 44.005 9.369 1.00 39.92 ? 494 LYS A CE 1 ATOM 3923 N NZ . LYS A 1 490 ? -17.685 44.417 9.798 1.00 40.30 ? 494 LYS A NZ 1 ATOM 3924 N N . GLY A 1 491 ? -16.068 41.795 4.040 1.00 32.37 ? 495 GLY A N 1 ATOM 3925 C CA . GLY A 1 491 ? -16.762 40.753 3.284 1.00 32.34 ? 495 GLY A CA 1 ATOM 3926 C C . GLY A 1 491 ? -16.987 41.027 1.809 1.00 32.07 ? 495 GLY A C 1 ATOM 3927 O O . GLY A 1 491 ? -17.580 40.212 1.108 1.00 31.86 ? 495 GLY A O 1 ATOM 3928 N N . ARG A 1 492 ? -16.515 42.176 1.341 1.00 32.09 ? 496 ARG A N 1 ATOM 3929 C CA . ARG A 1 492 ? -16.654 42.551 -0.065 1.00 32.19 ? 496 ARG A CA 1 ATOM 3930 C C . ARG A 1 492 ? -15.705 41.791 -0.972 1.00 32.16 ? 496 ARG A C 1 ATOM 3931 O O . ARG A 1 492 ? -15.985 41.632 -2.154 1.00 32.13 ? 496 ARG A O 1 ATOM 3932 C CB . ARG A 1 492 ? -16.494 44.054 -0.250 1.00 31.96 ? 496 ARG A CB 1 ATOM 3933 C CG . ARG A 1 492 ? -17.749 44.776 0.119 1.00 32.47 ? 496 ARG A CG 1 ATOM 3934 C CD . ARG A 1 492 ? -17.579 46.267 0.139 1.00 33.39 ? 496 ARG A CD 1 ATOM 3935 N NE . ARG A 1 492 ? -18.812 46.887 0.594 1.00 34.16 ? 496 ARG A NE 1 ATOM 3936 C CZ . ARG A 1 492 ? -19.140 47.027 1.871 1.00 35.67 ? 496 ARG A CZ 1 ATOM 3937 N NH1 . ARG A 1 492 ? -18.325 46.610 2.831 1.00 36.90 ? 496 ARG A NH1 1 ATOM 3938 N NH2 . ARG A 1 492 ? -20.285 47.589 2.190 1.00 37.12 ? 496 ARG A NH2 1 ATOM 3939 N N . ALA A 1 493 ? -14.581 41.341 -0.421 1.00 32.15 ? 497 ALA A N 1 ATOM 3940 C CA . ALA A 1 493 ? -13.685 40.473 -1.154 1.00 32.42 ? 497 ALA A CA 1 ATOM 3941 C C . ALA A 1 493 ? -13.185 39.340 -0.267 1.00 32.60 ? 497 ALA A C 1 ATOM 3942 O O . ALA A 1 493 ? -12.644 39.574 0.812 1.00 32.70 ? 497 ALA A O 1 ATOM 3943 C CB . ALA A 1 493 ? -12.533 41.258 -1.765 1.00 32.16 ? 497 ALA A CB 1 ATOM 3944 N N . CYS A 1 494 ? -13.394 38.112 -0.741 1.00 32.88 ? 498 CYS A N 1 ATOM 3945 C CA . CYS A 1 494 ? -13.013 36.906 -0.022 1.00 32.88 ? 498 CYS A CA 1 ATOM 3946 C C . CYS A 1 494 ? -11.972 36.129 -0.796 1.00 33.18 ? 498 CYS A C 1 ATOM 3947 O O . CYS A 1 494 ? -12.090 35.958 -2.012 1.00 33.13 ? 498 CYS A O 1 ATOM 3948 C CB . CYS A 1 494 ? -14.235 36.022 0.201 1.00 32.79 ? 498 CYS A CB 1 ATOM 3949 S SG . CYS A 1 494 ? -15.637 36.899 0.928 1.00 32.41 ? 498 CYS A SG 1 ATOM 3950 N N . ILE A 1 495 ? -10.943 35.672 -0.091 1.00 33.69 ? 499 ILE A N 1 ATOM 3951 C CA . ILE A 1 495 ? -9.963 34.760 -0.678 1.00 34.37 ? 499 ILE A CA 1 ATOM 3952 C C . ILE A 1 495 ? -9.610 33.644 0.307 1.00 35.03 ? 499 ILE A C 1 ATOM 3953 O O . ILE A 1 495 ? -9.175 33.901 1.440 1.00 35.36 ? 499 ILE A O 1 ATOM 3954 C CB . ILE A 1 495 ? -8.660 35.468 -1.128 1.00 34.20 ? 499 ILE A CB 1 ATOM 3955 C CG1 . ILE A 1 495 ? -8.941 36.584 -2.138 1.00 34.15 ? 499 ILE A CG1 1 ATOM 3956 C CG2 . ILE A 1 495 ? -7.713 34.456 -1.747 1.00 34.13 ? 499 ILE A CG2 1 ATOM 3957 C CD1 . ILE A 1 495 ? -7.829 37.604 -2.249 1.00 32.62 ? 499 ILE A CD1 1 ATOM 3958 N N . THR A 1 496 ? -9.810 32.410 -0.140 1.00 35.43 ? 500 THR A N 1 ATOM 3959 C CA . THR A 1 496 ? -9.367 31.230 0.584 1.00 35.74 ? 500 THR A CA 1 ATOM 3960 C C . THR A 1 496 ? -8.104 30.675 -0.082 1.00 36.23 ? 500 THR A C 1 ATOM 3961 O O . THR A 1 496 ? -7.991 30.650 -1.315 1.00 36.42 ? 500 THR A O 1 ATOM 3962 C CB . THR A 1 496 ? -10.470 30.168 0.576 1.00 35.68 ? 500 THR A CB 1 ATOM 3963 O OG1 . THR A 1 496 ? -11.717 30.792 0.916 1.00 36.14 ? 500 THR A OG1 1 ATOM 3964 C CG2 . THR A 1 496 ? -10.167 29.041 1.559 1.00 34.78 ? 500 THR A CG2 1 ATOM 3965 N N . SER A 1 497 ? -7.155 30.235 0.735 1.00 36.51 ? 501 SER A N 1 ATOM 3966 C CA . SER A 1 497 ? -5.930 29.630 0.233 1.00 36.68 ? 501 SER A CA 1 ATOM 3967 C C . SER A 1 497 ? -5.542 28.464 1.107 1.00 36.78 ? 501 SER A C 1 ATOM 3968 O O . SER A 1 497 ? -5.941 28.393 2.276 1.00 36.91 ? 501 SER A O 1 ATOM 3969 C CB . SER A 1 497 ? -4.807 30.636 0.285 1.00 36.60 ? 501 SER A CB 1 ATOM 3970 O OG . SER A 1 497 ? -4.528 30.910 1.640 1.00 37.46 ? 501 SER A OG 1 ATOM 3971 N N . ARG A 1 498 ? -4.735 27.567 0.551 1.00 36.90 ? 502 ARG A N 1 ATOM 3972 C CA . ARG A 1 498 ? -4.314 26.376 1.275 1.00 36.88 ? 502 ARG A CA 1 ATOM 3973 C C . ARG A 1 498 ? -2.800 26.292 1.294 1.00 37.11 ? 502 ARG A C 1 ATOM 3974 O O . ARG A 1 498 ? -2.176 26.075 0.262 1.00 37.25 ? 502 ARG A O 1 ATOM 3975 C CB . ARG A 1 498 ? -4.930 25.109 0.660 1.00 36.66 ? 502 ARG A CB 1 ATOM 3976 C CG . ARG A 1 498 ? -6.458 25.028 0.705 1.00 35.48 ? 502 ARG A CG 1 ATOM 3977 C CD . ARG A 1 498 ? -7.020 24.967 2.121 1.00 36.66 ? 502 ARG A CD 1 ATOM 3978 N NE . ARG A 1 498 ? -6.367 23.959 2.959 1.00 38.70 ? 502 ARG A NE 1 ATOM 3979 C CZ . ARG A 1 498 ? -6.625 22.650 2.910 1.00 39.95 ? 502 ARG A CZ 1 ATOM 3980 N NH1 . ARG A 1 498 ? -7.530 22.168 2.056 1.00 39.56 ? 502 ARG A NH1 1 ATOM 3981 N NH2 . ARG A 1 498 ? -5.969 21.815 3.711 1.00 39.74 ? 502 ARG A NH2 1 ATOM 3982 N N . VAL A 1 499 ? -2.215 26.477 2.471 1.00 37.38 ? 503 VAL A N 1 ATOM 3983 C CA . VAL A 1 499 ? -0.761 26.439 2.614 1.00 37.85 ? 503 VAL A CA 1 ATOM 3984 C C . VAL A 1 499 ? -0.319 25.365 3.611 1.00 38.33 ? 503 VAL A C 1 ATOM 3985 O O . VAL A 1 499 ? -1.066 25.008 4.516 1.00 38.67 ? 503 VAL A O 1 ATOM 3986 C CB . VAL A 1 499 ? -0.160 27.838 2.955 1.00 37.89 ? 503 VAL A CB 1 ATOM 3987 C CG1 . VAL A 1 499 ? -0.556 28.849 1.899 1.00 37.63 ? 503 VAL A CG1 1 ATOM 3988 C CG2 . VAL A 1 499 ? -0.575 28.322 4.343 1.00 37.09 ? 503 VAL A CG2 1 ATOM 3989 N N . TYR A 1 500 ? 0.886 24.835 3.423 1.00 38.97 ? 504 TYR A N 1 ATOM 3990 C CA . TYR A 1 500 ? 1.360 23.697 4.210 1.00 39.58 ? 504 TYR A CA 1 ATOM 3991 C C . TYR A 1 500 ? 2.789 23.942 4.685 1.00 40.53 ? 504 TYR A C 1 ATOM 3992 O O . TYR A 1 500 ? 3.741 23.376 4.142 1.00 40.52 ? 504 TYR A O 1 ATOM 3993 C CB . TYR A 1 500 ? 1.272 22.397 3.396 1.00 38.96 ? 504 TYR A CB 1 ATOM 3994 C CG . TYR A 1 500 ? -0.104 22.114 2.858 1.00 38.25 ? 504 TYR A CG 1 ATOM 3995 C CD1 . TYR A 1 500 ? -1.033 21.403 3.611 1.00 37.66 ? 504 TYR A CD1 1 ATOM 3996 C CD2 . TYR A 1 500 ? -0.485 22.571 1.601 1.00 37.63 ? 504 TYR A CD2 1 ATOM 3997 C CE1 . TYR A 1 500 ? -2.304 21.143 3.123 1.00 37.46 ? 504 TYR A CE1 1 ATOM 3998 C CE2 . TYR A 1 500 ? -1.754 22.325 1.105 1.00 37.99 ? 504 TYR A CE2 1 ATOM 3999 C CZ . TYR A 1 500 ? -2.660 21.607 1.869 1.00 38.29 ? 504 TYR A CZ 1 ATOM 4000 O OH . TYR A 1 500 ? -3.923 21.364 1.378 1.00 38.03 ? 504 TYR A OH 1 ATOM 4001 N N . PRO A 1 501 ? 2.945 24.793 5.707 1.00 41.49 ? 505 PRO A N 1 ATOM 4002 C CA . PRO A 1 501 ? 4.287 25.178 6.143 1.00 42.45 ? 505 PRO A CA 1 ATOM 4003 C C . PRO A 1 501 ? 5.065 24.008 6.749 1.00 43.36 ? 505 PRO A C 1 ATOM 4004 O O . PRO A 1 501 ? 4.481 23.157 7.423 1.00 43.38 ? 505 PRO A O 1 ATOM 4005 C CB . PRO A 1 501 ? 4.016 26.255 7.211 1.00 42.38 ? 505 PRO A CB 1 ATOM 4006 C CG . PRO A 1 501 ? 2.590 26.666 7.003 1.00 41.93 ? 505 PRO A CG 1 ATOM 4007 C CD . PRO A 1 501 ? 1.898 25.441 6.512 1.00 41.46 ? 505 PRO A CD 1 ATOM 4008 N N . LYS A 1 502 ? 6.368 23.971 6.482 1.00 44.47 ? 506 LYS A N 1 ATOM 4009 C CA . LYS A 1 502 ? 7.280 23.014 7.106 1.00 45.61 ? 506 LYS A CA 1 ATOM 4010 C C . LYS A 1 502 ? 7.766 23.498 8.476 1.00 46.18 ? 506 LYS A C 1 ATOM 4011 O O . LYS A 1 502 ? 7.902 22.702 9.404 1.00 46.43 ? 506 LYS A O 1 ATOM 4012 C CB . LYS A 1 502 ? 8.473 22.725 6.188 1.00 45.76 ? 506 LYS A CB 1 ATOM 4013 C CG . LYS A 1 502 ? 8.325 21.480 5.306 1.00 47.13 ? 506 LYS A CG 1 ATOM 4014 C CD . LYS A 1 502 ? 8.456 20.185 6.130 1.00 49.49 ? 506 LYS A CD 1 ATOM 4015 C CE . LYS A 1 502 ? 8.166 18.944 5.290 1.00 50.91 ? 506 LYS A CE 1 ATOM 4016 N NZ . LYS A 1 502 ? 9.283 18.656 4.333 1.00 52.20 ? 506 LYS A NZ 1 ATOM 4017 N N . LEU A 1 503 ? 8.013 24.800 8.595 1.00 46.85 ? 507 LEU A N 1 ATOM 4018 C CA . LEU A 1 503 ? 8.476 25.408 9.843 1.00 47.49 ? 507 LEU A CA 1 ATOM 4019 C C . LEU A 1 503 ? 7.367 26.000 10.710 1.00 47.92 ? 507 LEU A C 1 ATOM 4020 O O . LEU A 1 503 ? 7.273 25.673 11.892 1.00 48.12 ? 507 LEU A O 1 ATOM 4021 C CB . LEU A 1 503 ? 9.493 26.501 9.542 1.00 47.61 ? 507 LEU A CB 1 ATOM 4022 C CG . LEU A 1 503 ? 10.949 26.245 9.891 1.00 47.83 ? 507 LEU A CG 1 ATOM 4023 C CD1 . LEU A 1 503 ? 11.822 27.131 9.028 1.00 48.17 ? 507 LEU A CD1 1 ATOM 4024 C CD2 . LEU A 1 503 ? 11.172 26.526 11.379 1.00 47.84 ? 507 LEU A CD2 1 ATOM 4025 N N . ALA A 1 504 ? 6.555 26.887 10.130 1.00 48.53 ? 508 ALA A N 1 ATOM 4026 C CA . ALA A 1 504 ? 5.464 27.570 10.850 1.00 49.04 ? 508 ALA A CA 1 ATOM 4027 C C . ALA A 1 504 ? 4.313 26.634 11.208 1.00 49.52 ? 508 ALA A C 1 ATOM 4028 O O . ALA A 1 504 ? 3.268 26.632 10.557 1.00 49.65 ? 508 ALA A O 1 ATOM 4029 C CB . ALA A 1 504 ? 4.948 28.736 10.033 1.00 48.95 ? 508 ALA A CB 1 ATOM 4030 N N . ILE A 1 505 ? 4.512 25.838 12.249 1.00 50.14 ? 509 ILE A N 1 ATOM 4031 C CA . ILE A 1 505 ? 3.533 24.834 12.641 1.00 50.77 ? 509 ILE A CA 1 ATOM 4032 C C . ILE A 1 505 ? 3.207 24.922 14.141 1.00 51.34 ? 509 ILE A C 1 ATOM 4033 O O . ILE A 1 505 ? 4.116 25.081 14.978 1.00 51.16 ? 509 ILE A O 1 ATOM 4034 C CB . ILE A 1 505 ? 4.018 23.419 12.263 1.00 50.58 ? 509 ILE A CB 1 ATOM 4035 C CG1 . ILE A 1 505 ? 3.922 23.219 10.754 1.00 50.77 ? 509 ILE A CG1 1 ATOM 4036 C CG2 . ILE A 1 505 ? 3.209 22.347 12.985 1.00 51.01 ? 509 ILE A CG2 1 ATOM 4037 C CD1 . ILE A 1 505 ? 4.312 21.832 10.294 1.00 51.63 ? 509 ILE A CD1 1 ATOM 4038 N N . GLY A 1 506 ? 1.907 24.828 14.457 1.00 51.86 ? 510 GLY A N 1 ATOM 4039 C CA . GLY A 1 506 ? 1.395 24.856 15.837 1.00 52.22 ? 510 GLY A CA 1 ATOM 4040 C C . GLY A 1 506 ? 1.963 25.988 16.676 1.00 52.61 ? 510 GLY A C 1 ATOM 4041 O O . GLY A 1 506 ? 1.768 27.170 16.367 1.00 52.81 ? 510 GLY A O 1 ATOM 4042 N N . LYS A 1 507 ? 2.693 25.620 17.724 1.00 52.78 ? 511 LYS A N 1 ATOM 4043 C CA . LYS A 1 507 ? 3.319 26.594 18.623 1.00 53.11 ? 511 LYS A CA 1 ATOM 4044 C C . LYS A 1 507 ? 4.447 27.408 17.968 1.00 52.72 ? 511 LYS A C 1 ATOM 4045 O O . LYS A 1 507 ? 4.821 28.469 18.469 1.00 52.66 ? 511 LYS A O 1 ATOM 4046 C CB . LYS A 1 507 ? 3.818 25.901 19.906 1.00 53.22 ? 511 LYS A CB 1 ATOM 4047 C CG . LYS A 1 507 ? 4.861 24.776 19.682 1.00 54.10 ? 511 LYS A CG 1 ATOM 4048 C CD . LYS A 1 507 ? 4.877 23.743 20.829 1.00 53.97 ? 511 LYS A CD 1 ATOM 4049 C CE . LYS A 1 507 ? 5.301 24.358 22.175 1.00 55.69 ? 511 LYS A CE 1 ATOM 4050 N NZ . LYS A 1 507 ? 6.733 24.817 22.209 1.00 55.72 ? 511 LYS A NZ 1 ATOM 4051 N N . SER A 1 508 ? 4.979 26.922 16.850 1.00 52.38 ? 512 SER A N 1 ATOM 4052 C CA . SER A 1 508 ? 6.095 27.604 16.192 1.00 52.14 ? 512 SER A CA 1 ATOM 4053 C C . SER A 1 508 ? 5.698 28.625 15.109 1.00 52.10 ? 512 SER A C 1 ATOM 4054 O O . SER A 1 508 ? 6.564 29.140 14.384 1.00 52.48 ? 512 SER A O 1 ATOM 4055 C CB . SER A 1 508 ? 7.090 26.587 15.644 1.00 51.83 ? 512 SER A CB 1 ATOM 4056 O OG . SER A 1 508 ? 7.727 25.937 16.718 1.00 51.25 ? 512 SER A OG 1 ATOM 4057 N N . SER A 1 509 ? 4.403 28.922 15.012 1.00 51.58 ? 513 SER A N 1 ATOM 4058 C CA . SER A 1 509 ? 3.904 29.859 14.013 1.00 51.17 ? 513 SER A CA 1 ATOM 4059 C C . SER A 1 509 ? 3.702 31.245 14.606 1.00 50.84 ? 513 SER A C 1 ATOM 4060 O O . SER A 1 509 ? 3.311 31.383 15.764 1.00 50.75 ? 513 SER A O 1 ATOM 4061 C CB . SER A 1 509 ? 2.589 29.358 13.422 1.00 51.22 ? 513 SER A CB 1 ATOM 4062 O OG . SER A 1 509 ? 1.559 29.405 14.392 1.00 51.62 ? 513 SER A OG 1 ATOM 4063 N N . HIS A 1 510 ? 3.956 32.267 13.798 1.00 50.48 ? 514 HIS A N 1 ATOM 4064 C CA . HIS A 1 510 ? 3.780 33.648 14.231 1.00 50.12 ? 514 HIS A CA 1 ATOM 4065 C C . HIS A 1 510 ? 2.807 34.445 13.354 1.00 49.76 ? 514 HIS A C 1 ATOM 4066 O O . HIS A 1 510 ? 2.396 34.001 12.277 1.00 49.74 ? 514 HIS A O 1 ATOM 4067 C CB . HIS A 1 510 ? 5.137 34.346 14.349 1.00 50.25 ? 514 HIS A CB 1 ATOM 4068 C CG . HIS A 1 510 ? 6.043 33.710 15.352 1.00 50.92 ? 514 HIS A CG 1 ATOM 4069 N ND1 . HIS A 1 510 ? 6.213 34.212 16.625 1.00 51.30 ? 514 HIS A ND1 1 ATOM 4070 C CD2 . HIS A 1 510 ? 6.803 32.591 15.281 1.00 51.13 ? 514 HIS A CD2 1 ATOM 4071 C CE1 . HIS A 1 510 ? 7.049 33.436 17.291 1.00 52.14 ? 514 HIS A CE1 1 ATOM 4072 N NE2 . HIS A 1 510 ? 7.417 32.442 16.499 1.00 51.78 ? 514 HIS A NE2 1 ATOM 4073 N N . LEU A 1 511 ? 2.438 35.623 13.848 1.00 49.40 ? 515 LEU A N 1 ATOM 4074 C CA . LEU A 1 511 ? 1.467 36.488 13.212 1.00 48.78 ? 515 LEU A CA 1 ATOM 4075 C C . LEU A 1 511 ? 2.043 37.893 13.157 1.00 48.86 ? 515 LEU A C 1 ATOM 4076 O O . LEU A 1 511 ? 2.443 38.459 14.180 1.00 49.08 ? 515 LEU A O 1 ATOM 4077 C CB . LEU A 1 511 ? 0.169 36.470 14.018 1.00 48.60 ? 515 LEU A CB 1 ATOM 4078 C CG . LEU A 1 511 ? -1.049 37.289 13.589 1.00 48.40 ? 515 LEU A CG 1 ATOM 4079 C CD1 . LEU A 1 511 ? -1.580 36.868 12.227 1.00 47.67 ? 515 LEU A CD1 1 ATOM 4080 C CD2 . LEU A 1 511 ? -2.139 37.164 14.647 1.00 48.62 ? 515 LEU A CD2 1 ATOM 4081 N N . PHE A 1 512 ? 2.102 38.460 11.960 1.00 48.74 ? 516 PHE A N 1 ATOM 4082 C CA . PHE A 1 512 ? 2.589 39.824 11.820 1.00 48.38 ? 516 PHE A CA 1 ATOM 4083 C C . PHE A 1 512 ? 1.580 40.713 11.128 1.00 48.11 ? 516 PHE A C 1 ATOM 4084 O O . PHE A 1 512 ? 0.696 40.234 10.417 1.00 47.94 ? 516 PHE A O 1 ATOM 4085 C CB . PHE A 1 512 ? 3.898 39.846 11.045 1.00 48.29 ? 516 PHE A CB 1 ATOM 4086 C CG . PHE A 1 512 ? 5.030 39.182 11.757 1.00 48.56 ? 516 PHE A CG 1 ATOM 4087 C CD1 . PHE A 1 512 ? 5.899 39.927 12.550 1.00 48.63 ? 516 PHE A CD1 1 ATOM 4088 C CD2 . PHE A 1 512 ? 5.242 37.812 11.628 1.00 48.89 ? 516 PHE A CD2 1 ATOM 4089 C CE1 . PHE A 1 512 ? 6.959 39.319 13.203 1.00 48.87 ? 516 PHE A CE1 1 ATOM 4090 C CE2 . PHE A 1 512 ? 6.305 37.188 12.281 1.00 48.83 ? 516 PHE A CE2 1 ATOM 4091 C CZ . PHE A 1 512 ? 7.165 37.943 13.070 1.00 48.80 ? 516 PHE A CZ 1 ATOM 4092 N N . ALA A 1 513 ? 1.706 42.011 11.387 1.00 47.83 ? 517 ALA A N 1 ATOM 4093 C CA . ALA A 1 513 ? 1.136 43.043 10.528 1.00 47.38 ? 517 ALA A CA 1 ATOM 4094 C C . ALA A 1 513 ? 2.343 43.736 9.927 1.00 46.98 ? 517 ALA A C 1 ATOM 4095 O O . ALA A 1 513 ? 3.319 43.983 10.630 1.00 47.16 ? 517 ALA A O 1 ATOM 4096 C CB . ALA A 1 513 ? 0.295 44.013 11.322 1.00 47.19 ? 517 ALA A CB 1 ATOM 4097 N N . PHE A 1 514 ? 2.307 44.002 8.626 1.00 46.49 ? 518 PHE A N 1 ATOM 4098 C CA . PHE A 1 514 ? 3.479 44.537 7.945 1.00 46.00 ? 518 PHE A CA 1 ATOM 4099 C C . PHE A 1 514 ? 3.137 45.696 7.014 1.00 45.91 ? 518 PHE A C 1 ATOM 4100 O O . PHE A 1 514 ? 1.963 46.042 6.830 1.00 45.47 ? 518 PHE A O 1 ATOM 4101 C CB . PHE A 1 514 ? 4.220 43.426 7.191 1.00 45.92 ? 518 PHE A CB 1 ATOM 4102 C CG . PHE A 1 514 ? 3.523 42.974 5.938 1.00 45.94 ? 518 PHE A CG 1 ATOM 4103 C CD1 . PHE A 1 514 ? 3.943 43.430 4.694 1.00 45.53 ? 518 PHE A CD1 1 ATOM 4104 C CD2 . PHE A 1 514 ? 2.437 42.106 5.999 1.00 45.95 ? 518 PHE A CD2 1 ATOM 4105 C CE1 . PHE A 1 514 ? 3.296 43.031 3.537 1.00 45.11 ? 518 PHE A CE1 1 ATOM 4106 C CE2 . PHE A 1 514 ? 1.784 41.703 4.846 1.00 45.54 ? 518 PHE A CE2 1 ATOM 4107 C CZ . PHE A 1 514 ? 2.219 42.163 3.613 1.00 45.57 ? 518 PHE A CZ 1 ATOM 4108 N N . ASN A 1 515 ? 4.188 46.291 6.451 1.00 45.91 ? 519 ASN A N 1 ATOM 4109 C CA . ASN A 1 515 ? 4.083 47.395 5.510 1.00 46.08 ? 519 ASN A CA 1 ATOM 4110 C C . ASN A 1 515 ? 5.387 47.612 4.766 1.00 46.45 ? 519 ASN A C 1 ATOM 4111 O O . ASN A 1 515 ? 6.360 48.106 5.334 1.00 46.58 ? 519 ASN A O 1 ATOM 4112 C CB . ASN A 1 515 ? 3.679 48.692 6.213 1.00 45.90 ? 519 ASN A CB 1 ATOM 4113 C CG . ASN A 1 515 ? 3.572 49.862 5.252 1.00 45.65 ? 519 ASN A CG 1 ATOM 4114 O OD1 . ASN A 1 515 ? 3.422 49.684 4.046 1.00 45.56 ? 519 ASN A OD1 1 ATOM 4115 N ND2 . ASN A 1 515 ? 3.658 51.067 5.784 1.00 46.79 ? 519 ASN A ND2 1 ATOM 4116 N N . TYR A 1 516 ? 5.400 47.254 3.489 1.00 46.92 ? 520 TYR A N 1 ATOM 4117 C CA . TYR A 1 516 ? 6.584 47.434 2.658 1.00 47.47 ? 520 TYR A CA 1 ATOM 4118 C C . TYR A 1 516 ? 6.390 48.525 1.595 1.00 48.07 ? 520 TYR A C 1 ATOM 4119 O O . TYR A 1 516 ? 7.152 48.612 0.624 1.00 48.18 ? 520 TYR A O 1 ATOM 4120 C CB . TYR A 1 516 ? 7.010 46.102 2.028 1.00 47.31 ? 520 TYR A CB 1 ATOM 4121 C CG . TYR A 1 516 ? 7.396 45.036 3.034 1.00 47.22 ? 520 TYR A CG 1 ATOM 4122 C CD1 . TYR A 1 516 ? 7.374 43.689 2.685 1.00 46.69 ? 520 TYR A CD1 1 ATOM 4123 C CD2 . TYR A 1 516 ? 7.786 45.373 4.339 1.00 46.77 ? 520 TYR A CD2 1 ATOM 4124 C CE1 . TYR A 1 516 ? 7.731 42.708 3.600 1.00 46.07 ? 520 TYR A CE1 1 ATOM 4125 C CE2 . TYR A 1 516 ? 8.137 44.403 5.259 1.00 45.90 ? 520 TYR A CE2 1 ATOM 4126 C CZ . TYR A 1 516 ? 8.108 43.074 4.878 1.00 46.75 ? 520 TYR A CZ 1 ATOM 4127 O OH . TYR A 1 516 ? 8.466 42.104 5.779 1.00 48.05 ? 520 TYR A OH 1 ATOM 4128 N N . GLY A 1 517 ? 5.373 49.361 1.790 1.00 48.60 ? 521 GLY A N 1 ATOM 4129 C CA . GLY A 1 517 ? 5.163 50.517 0.928 1.00 49.56 ? 521 GLY A CA 1 ATOM 4130 C C . GLY A 1 517 ? 6.195 51.611 1.156 1.00 50.06 ? 521 GLY A C 1 ATOM 4131 O O . GLY A 1 517 ? 7.036 51.517 2.059 1.00 50.15 ? 521 GLY A O 1 ATOM 4132 N N . TYR A 1 518 ? 6.135 52.651 0.330 1.00 50.43 ? 522 TYR A N 1 ATOM 4133 C CA . TYR A 1 518 ? 6.979 53.820 0.514 1.00 50.55 ? 522 TYR A CA 1 ATOM 4134 C C . TYR A 1 518 ? 6.473 54.688 1.666 1.00 50.74 ? 522 TYR A C 1 ATOM 4135 O O . TYR A 1 518 ? 7.255 55.378 2.323 1.00 50.70 ? 522 TYR A O 1 ATOM 4136 C CB . TYR A 1 518 ? 7.001 54.648 -0.757 1.00 50.67 ? 522 TYR A CB 1 ATOM 4137 C CG . TYR A 1 518 ? 7.887 54.122 -1.861 1.00 50.98 ? 522 TYR A CG 1 ATOM 4138 C CD1 . TYR A 1 518 ? 7.347 53.768 -3.094 1.00 51.06 ? 522 TYR A CD1 1 ATOM 4139 C CD2 . TYR A 1 518 ? 9.271 54.013 -1.688 1.00 51.37 ? 522 TYR A CD2 1 ATOM 4140 C CE1 . TYR A 1 518 ? 8.158 53.307 -4.134 1.00 52.04 ? 522 TYR A CE1 1 ATOM 4141 C CE2 . TYR A 1 518 ? 10.097 53.550 -2.720 1.00 51.81 ? 522 TYR A CE2 1 ATOM 4142 C CZ . TYR A 1 518 ? 9.533 53.197 -3.943 1.00 51.98 ? 522 TYR A CZ 1 ATOM 4143 O OH . TYR A 1 518 ? 10.329 52.739 -4.979 1.00 51.51 ? 522 TYR A OH 1 ATOM 4144 N N . GLN A 1 519 ? 5.160 54.659 1.889 1.00 50.97 ? 523 GLN A N 1 ATOM 4145 C CA . GLN A 1 519 ? 4.510 55.502 2.889 1.00 51.14 ? 523 GLN A CA 1 ATOM 4146 C C . GLN A 1 519 ? 4.144 54.676 4.098 1.00 51.05 ? 523 GLN A C 1 ATOM 4147 O O . GLN A 1 519 ? 3.764 53.515 3.970 1.00 51.21 ? 523 GLN A O 1 ATOM 4148 C CB . GLN A 1 519 ? 3.231 56.131 2.329 1.00 51.36 ? 523 GLN A CB 1 ATOM 4149 C CG . GLN A 1 519 ? 3.370 56.833 0.980 1.00 52.33 ? 523 GLN A CG 1 ATOM 4150 C CD . GLN A 1 519 ? 4.359 57.989 1.003 1.00 53.65 ? 523 GLN A CD 1 ATOM 4151 O OE1 . GLN A 1 519 ? 4.434 58.745 1.978 1.00 53.87 ? 523 GLN A OE1 1 ATOM 4152 N NE2 . GLN A 1 519 ? 5.125 58.134 -0.081 1.00 53.86 ? 523 GLN A NE2 1 ATOM 4153 N N . SER A 1 520 ? 4.250 55.276 5.274 1.00 51.13 ? 524 SER A N 1 ATOM 4154 C CA . SER A 1 520 ? 3.859 54.583 6.488 1.00 51.38 ? 524 SER A CA 1 ATOM 4155 C C . SER A 1 520 ? 2.335 54.615 6.616 1.00 51.33 ? 524 SER A C 1 ATOM 4156 O O . SER A 1 520 ? 1.685 55.577 6.192 1.00 51.55 ? 524 SER A O 1 ATOM 4157 C CB . SER A 1 520 ? 4.545 55.189 7.712 1.00 51.42 ? 524 SER A CB 1 ATOM 4158 O OG . SER A 1 520 ? 4.054 56.486 7.992 1.00 52.35 ? 524 SER A OG 1 ATOM 4159 N N . VAL A 1 521 ? 1.772 53.548 7.171 1.00 50.91 ? 525 VAL A N 1 ATOM 4160 C CA . VAL A 1 521 ? 0.330 53.428 7.318 1.00 50.49 ? 525 VAL A CA 1 ATOM 4161 C C . VAL A 1 521 ? 0.016 53.144 8.768 1.00 50.35 ? 525 VAL A C 1 ATOM 4162 O O . VAL A 1 521 ? 0.827 52.549 9.479 1.00 50.48 ? 525 VAL A O 1 ATOM 4163 C CB . VAL A 1 521 ? -0.268 52.311 6.414 1.00 50.47 ? 525 VAL A CB 1 ATOM 4164 C CG1 . VAL A 1 521 ? -0.228 52.720 4.952 1.00 50.42 ? 525 VAL A CG1 1 ATOM 4165 C CG2 . VAL A 1 521 ? 0.464 50.981 6.616 1.00 50.61 ? 525 VAL A CG2 1 ATOM 4166 N N . ASP A 1 522 ? -1.167 53.563 9.198 1.00 50.21 ? 526 ASP A N 1 ATOM 4167 C CA . ASP A 1 522 ? -1.569 53.434 10.589 1.00 50.06 ? 526 ASP A CA 1 ATOM 4168 C C . ASP A 1 522 ? -2.436 52.203 10.823 1.00 49.79 ? 526 ASP A C 1 ATOM 4169 O O . ASP A 1 522 ? -3.392 51.956 10.087 1.00 49.89 ? 526 ASP A O 1 ATOM 4170 C CB . ASP A 1 522 ? -2.297 54.703 11.050 1.00 50.09 ? 526 ASP A CB 1 ATOM 4171 C CG . ASP A 1 522 ? -1.380 55.927 11.100 1.00 50.91 ? 526 ASP A CG 1 ATOM 4172 O OD1 . ASP A 1 522 ? -0.238 55.865 10.593 1.00 51.98 ? 526 ASP A OD1 1 ATOM 4173 O OD2 . ASP A 1 522 ? -1.803 56.964 11.651 1.00 51.56 ? 526 ASP A OD2 1 ATOM 4174 N N . VAL A 1 523 ? -2.075 51.423 11.838 1.00 49.34 ? 527 VAL A N 1 ATOM 4175 C CA . VAL A 1 523 ? -2.946 50.377 12.340 1.00 48.93 ? 527 VAL A CA 1 ATOM 4176 C C . VAL A 1 523 ? -3.807 51.040 13.400 1.00 48.68 ? 527 VAL A C 1 ATOM 4177 O O . VAL A 1 523 ? -3.358 51.251 14.522 1.00 48.73 ? 527 VAL A O 1 ATOM 4178 C CB . VAL A 1 523 ? -2.162 49.171 12.946 1.00 49.06 ? 527 VAL A CB 1 ATOM 4179 C CG1 . VAL A 1 523 ? -3.112 48.190 13.654 1.00 49.02 ? 527 VAL A CG1 1 ATOM 4180 C CG2 . VAL A 1 523 ? -1.360 48.438 11.872 1.00 48.76 ? 527 VAL A CG2 1 ATOM 4181 N N . LEU A 1 524 ? -5.032 51.397 13.017 1.00 48.45 ? 528 LEU A N 1 ATOM 4182 C CA . LEU A 1 524 ? -6.030 51.945 13.935 1.00 48.23 ? 528 LEU A CA 1 ATOM 4183 C C . LEU A 1 524 ? -6.316 50.988 15.070 1.00 47.95 ? 528 LEU A C 1 ATOM 4184 O O . LEU A 1 524 ? -6.276 51.367 16.240 1.00 48.04 ? 528 LEU A O 1 ATOM 4185 C CB . LEU A 1 524 ? -7.347 52.181 13.208 1.00 48.31 ? 528 LEU A CB 1 ATOM 4186 C CG . LEU A 1 524 ? -7.857 53.577 12.902 1.00 49.05 ? 528 LEU A CG 1 ATOM 4187 C CD1 . LEU A 1 524 ? -9.196 53.432 12.181 1.00 49.66 ? 528 LEU A CD1 1 ATOM 4188 C CD2 . LEU A 1 524 ? -8.016 54.398 14.177 1.00 49.33 ? 528 LEU A CD2 1 ATOM 4189 N N . ASN A 1 525 ? -6.625 49.747 14.703 1.00 47.52 ? 529 ASN A N 1 ATOM 4190 C CA . ASN A 1 525 ? -7.047 48.732 15.652 1.00 47.02 ? 529 ASN A CA 1 ATOM 4191 C C . ASN A 1 525 ? -6.781 47.348 15.104 1.00 46.77 ? 529 ASN A C 1 ATOM 4192 O O . ASN A 1 525 ? -6.991 47.098 13.921 1.00 47.15 ? 529 ASN A O 1 ATOM 4193 C CB . ASN A 1 525 ? -8.535 48.874 15.954 1.00 46.75 ? 529 ASN A CB 1 ATOM 4194 C CG . ASN A 1 525 ? -8.960 48.053 17.137 1.00 46.52 ? 529 ASN A CG 1 ATOM 4195 O OD1 . ASN A 1 525 ? -8.248 47.974 18.134 1.00 47.07 ? 529 ASN A OD1 1 ATOM 4196 N ND2 . ASN A 1 525 ? -10.122 47.433 17.042 1.00 46.56 ? 529 ASN A ND2 1 ATOM 4197 N N . LEU A 1 526 ? -6.311 46.453 15.961 1.00 46.19 ? 530 LEU A N 1 ATOM 4198 C CA . LEU A 1 526 ? -6.079 45.081 15.562 1.00 45.93 ? 530 LEU A CA 1 ATOM 4199 C C . LEU A 1 526 ? -6.470 44.188 16.710 1.00 45.90 ? 530 LEU A C 1 ATOM 4200 O O . LEU A 1 526 ? -6.045 44.401 17.840 1.00 45.96 ? 530 LEU A O 1 ATOM 4201 C CB . LEU A 1 526 ? -4.623 44.880 15.106 1.00 46.06 ? 530 LEU A CB 1 ATOM 4202 C CG . LEU A 1 526 ? -3.690 43.644 15.155 1.00 46.09 ? 530 LEU A CG 1 ATOM 4203 C CD1 . LEU A 1 526 ? -4.334 42.271 15.317 1.00 45.27 ? 530 LEU A CD1 1 ATOM 4204 C CD2 . LEU A 1 526 ? -2.774 43.654 13.925 1.00 45.95 ? 530 LEU A CD2 1 ATOM 4205 N N . ASN A 1 527 ? -7.323 43.214 16.406 1.00 45.76 ? 531 ASN A N 1 ATOM 4206 C CA . ASN A 1 527 ? -7.766 42.227 17.369 1.00 45.63 ? 531 ASN A CA 1 ATOM 4207 C C . ASN A 1 527 ? -7.380 40.847 16.896 1.00 45.27 ? 531 ASN A C 1 ATOM 4208 O O . ASN A 1 527 ? -7.642 40.478 15.748 1.00 45.34 ? 531 ASN A O 1 ATOM 4209 C CB . ASN A 1 527 ? -9.286 42.288 17.552 1.00 45.94 ? 531 ASN A CB 1 ATOM 4210 C CG . ASN A 1 527 ? -9.734 43.435 18.446 1.00 46.82 ? 531 ASN A CG 1 ATOM 4211 O OD1 . ASN A 1 527 ? -9.069 43.786 19.425 1.00 48.38 ? 531 ASN A OD1 1 ATOM 4212 N ND2 . ASN A 1 527 ? -10.876 44.016 18.117 1.00 47.26 ? 531 ASN A ND2 1 ATOM 4213 N N . ALA A 1 528 ? -6.750 40.089 17.783 1.00 44.86 ? 532 ALA A N 1 ATOM 4214 C CA . ALA A 1 528 ? -6.428 38.699 17.513 1.00 44.37 ? 532 ALA A CA 1 ATOM 4215 C C . ALA A 1 528 ? -7.004 37.849 18.631 1.00 44.08 ? 532 ALA A C 1 ATOM 4216 O O . ALA A 1 528 ? -6.715 38.087 19.800 1.00 44.25 ? 532 ALA A O 1 ATOM 4217 C CB . ALA A 1 528 ? -4.924 38.514 17.412 1.00 44.23 ? 532 ALA A CB 1 ATOM 4218 N N . TRP A 1 529 ? -7.846 36.888 18.267 1.00 43.81 ? 533 TRP A N 1 ATOM 4219 C CA . TRP A 1 529 ? -8.378 35.908 19.211 1.00 43.65 ? 533 TRP A CA 1 ATOM 4220 C C . TRP A 1 529 ? -7.817 34.547 18.894 1.00 43.41 ? 533 TRP A C 1 ATOM 4221 O O . TRP A 1 529 ? -7.853 34.115 17.737 1.00 43.81 ? 533 TRP A O 1 ATOM 4222 C CB . TRP A 1 529 ? -9.894 35.792 19.094 1.00 43.67 ? 533 TRP A CB 1 ATOM 4223 C CG . TRP A 1 529 ? -10.641 37.002 19.491 1.00 43.88 ? 533 TRP A CG 1 ATOM 4224 C CD1 . TRP A 1 529 ? -11.079 37.315 20.739 1.00 43.95 ? 533 TRP A CD1 1 ATOM 4225 C CD2 . TRP A 1 529 ? -11.072 38.064 18.631 1.00 43.75 ? 533 TRP A CD2 1 ATOM 4226 N NE1 . TRP A 1 529 ? -11.750 38.515 20.720 1.00 44.06 ? 533 TRP A NE1 1 ATOM 4227 C CE2 . TRP A 1 529 ? -11.764 38.997 19.437 1.00 43.97 ? 533 TRP A CE2 1 ATOM 4228 C CE3 . TRP A 1 529 ? -10.939 38.322 17.261 1.00 43.35 ? 533 TRP A CE3 1 ATOM 4229 C CZ2 . TRP A 1 529 ? -12.321 40.176 18.917 1.00 43.53 ? 533 TRP A CZ2 1 ATOM 4230 C CZ3 . TRP A 1 529 ? -11.496 39.494 16.743 1.00 44.04 ? 533 TRP A CZ3 1 ATOM 4231 C CH2 . TRP A 1 529 ? -12.177 40.407 17.576 1.00 43.85 ? 533 TRP A CH2 1 ATOM 4232 N N . SER A 1 530 ? -7.319 33.857 19.914 1.00 42.98 ? 534 SER A N 1 ATOM 4233 C CA . SER A 1 530 ? -7.024 32.434 19.773 1.00 42.48 ? 534 SER A CA 1 ATOM 4234 C C . SER A 1 530 ? -8.339 31.708 19.547 1.00 42.27 ? 534 SER A C 1 ATOM 4235 O O . SER A 1 530 ? -9.352 32.031 20.160 1.00 42.08 ? 534 SER A O 1 ATOM 4236 C CB . SER A 1 530 ? -6.299 31.886 21.001 1.00 42.32 ? 534 SER A CB 1 ATOM 4237 O OG . SER A 1 530 ? -4.927 32.260 20.993 1.00 41.66 ? 534 SER A OG 1 ATOM 4238 N N . MET A 1 531 ? -8.336 30.754 18.632 1.00 42.51 ? 535 MET A N 1 ATOM 4239 C CA . MET A 1 531 ? -9.552 30.017 18.332 1.00 42.69 ? 535 MET A CA 1 ATOM 4240 C C . MET A 1 531 ? -9.518 28.626 18.943 1.00 43.07 ? 535 MET A C 1 ATOM 4241 O O . MET A 1 531 ? -8.586 27.858 18.719 1.00 43.03 ? 535 MET A O 1 ATOM 4242 C CB . MET A 1 531 ? -9.778 29.951 16.821 1.00 42.64 ? 535 MET A CB 1 ATOM 4243 C CG . MET A 1 531 ? -10.149 31.286 16.193 1.00 41.55 ? 535 MET A CG 1 ATOM 4244 S SD . MET A 1 531 ? -11.834 31.764 16.579 1.00 40.90 ? 535 MET A SD 1 ATOM 4245 C CE . MET A 1 531 ? -12.753 30.794 15.380 1.00 41.87 ? 535 MET A CE 1 ATOM 4246 N N . ASN A 1 532 ? -10.535 28.320 19.734 1.00 43.64 ? 536 ASN A N 1 ATOM 4247 C CA . ASN A 1 532 ? -10.709 26.987 20.279 1.00 44.48 ? 536 ASN A CA 1 ATOM 4248 C C . ASN A 1 532 ? -11.118 26.001 19.202 1.00 45.02 ? 536 ASN A C 1 ATOM 4249 O O . ASN A 1 532 ? -11.716 26.384 18.196 1.00 44.86 ? 536 ASN A O 1 ATOM 4250 C CB . ASN A 1 532 ? -11.762 27.006 21.380 1.00 44.60 ? 536 ASN A CB 1 ATOM 4251 C CG . ASN A 1 532 ? -11.204 27.476 22.706 1.00 45.13 ? 536 ASN A CG 1 ATOM 4252 O OD1 . ASN A 1 532 ? -10.353 26.811 23.304 1.00 46.50 ? 536 ASN A OD1 1 ATOM 4253 N ND2 . ASN A 1 532 ? -11.681 28.621 23.178 1.00 44.69 ? 536 ASN A ND2 1 ATOM 4254 N N . SER A 1 533 ? -10.798 24.730 19.418 1.00 45.92 ? 537 SER A N 1 ATOM 4255 C CA . SER A 1 533 ? -11.178 23.679 18.478 1.00 46.68 ? 537 SER A CA 1 ATOM 4256 C C . SER A 1 533 ? -12.678 23.410 18.488 1.00 47.34 ? 537 SER A C 1 ATOM 4257 O O . SER A 1 533 ? -13.355 23.661 19.483 1.00 47.62 ? 537 SER A O 1 ATOM 4258 C CB . SER A 1 533 ? -10.424 22.397 18.783 1.00 46.51 ? 537 SER A CB 1 ATOM 4259 O OG . SER A 1 533 ? -9.098 22.498 18.324 1.00 46.91 ? 537 SER A OG 1 ATOM 4260 N N . ALA A 1 534 ? -13.191 22.907 17.371 1.00 48.22 ? 538 ALA A N 1 ATOM 4261 C CA . ALA A 1 534 ? -14.592 22.543 17.273 1.00 48.96 ? 538 ALA A CA 1 ATOM 4262 C C . ALA A 1 534 ? -14.747 21.043 17.454 1.00 49.70 ? 538 ALA A C 1 ATOM 4263 O O . ALA A 1 534 ? -13.784 20.290 17.319 1.00 49.87 ? 538 ALA A O 1 ATOM 4264 C CB . ALA A 1 534 ? -15.157 22.981 15.941 1.00 48.88 ? 538 ALA A CB 1 ATOM 4265 N N . GLN A 1 535 ? -15.963 20.626 17.783 1.00 50.69 ? 539 GLN A N 1 ATOM 4266 C CA . GLN A 1 535 ? -16.323 19.225 17.896 1.00 51.87 ? 539 GLN A CA 1 ATOM 4267 C C . GLN A 1 535 ? -16.875 18.805 16.531 1.00 52.23 ? 539 GLN A C 1 ATOM 4268 O O . GLN A 1 535 ? -18.047 19.041 16.216 1.00 52.50 ? 539 GLN A O 1 ATOM 4269 C CB . GLN A 1 535 ? -17.357 19.050 19.031 1.00 52.35 ? 539 GLN A CB 1 ATOM 4270 C CG . GLN A 1 535 ? -18.077 17.685 19.125 1.00 53.94 ? 539 GLN A CG 1 ATOM 4271 C CD . GLN A 1 535 ? -17.333 16.658 19.980 1.00 55.46 ? 539 GLN A CD 1 ATOM 4272 O OE1 . GLN A 1 535 ? -16.179 16.304 19.700 1.00 55.75 ? 539 GLN A OE1 1 ATOM 4273 N NE2 . GLN A 1 535 ? -18.004 16.162 21.020 1.00 55.54 ? 539 GLN A NE2 1 ATOM 4274 N N . ILE A 1 536 ? -16.009 18.224 15.707 1.00 52.60 ? 540 ILE A N 1 ATOM 4275 C CA . ILE A 1 536 ? -16.378 17.793 14.358 1.00 53.16 ? 540 ILE A CA 1 ATOM 4276 C C . ILE A 1 536 ? -15.921 16.353 14.180 1.00 53.77 ? 540 ILE A C 1 ATOM 4277 O O . ILE A 1 536 ? -14.805 16.023 14.578 1.00 54.19 ? 540 ILE A O 1 ATOM 4278 C CB . ILE A 1 536 ? -15.695 18.661 13.285 1.00 52.90 ? 540 ILE A CB 1 ATOM 4279 C CG1 . ILE A 1 536 ? -16.013 20.144 13.499 1.00 52.53 ? 540 ILE A CG1 1 ATOM 4280 C CG2 . ILE A 1 536 ? -16.122 18.214 11.895 1.00 53.09 ? 540 ILE A CG2 1 ATOM 4281 C CD1 . ILE A 1 536 ? -14.982 21.083 12.912 1.00 51.88 ? 540 ILE A CD1 1 ATOM 4282 N N . SER A 1 537 ? -16.770 15.509 13.582 1.00 54.39 ? 541 SER A N 1 ATOM 4283 C CA . SER A 1 537 ? -16.518 14.049 13.442 1.00 54.62 ? 541 SER A CA 1 ATOM 4284 C C . SER A 1 537 ? -15.052 13.623 13.215 1.00 54.96 ? 541 SER A C 1 ATOM 4285 O O . SER A 1 537 ? -14.295 14.245 12.450 1.00 55.38 ? 541 SER A O 1 ATOM 4286 C CB . SER A 1 537 ? -17.435 13.412 12.377 1.00 54.67 ? 541 SER A CB 1 ATOM 4287 O OG . SER A 1 537 ? -18.078 14.373 11.545 1.00 54.44 ? 541 SER A OG 1 HETATM 4288 C C1 . NAG B 2 . ? -7.596 21.222 -6.525 1.00 35.31 ? 750 NAG A C1 1 HETATM 4289 C C2 . NAG B 2 . ? -8.190 22.310 -7.392 1.00 36.19 ? 750 NAG A C2 1 HETATM 4290 C C3 . NAG B 2 . ? -7.349 22.422 -8.646 1.00 36.54 ? 750 NAG A C3 1 HETATM 4291 C C4 . NAG B 2 . ? -5.889 22.648 -8.277 1.00 39.01 ? 750 NAG A C4 1 HETATM 4292 C C5 . NAG B 2 . ? -5.384 21.600 -7.283 1.00 37.73 ? 750 NAG A C5 1 HETATM 4293 C C6 . NAG B 2 . ? -3.989 21.954 -6.773 1.00 38.06 ? 750 NAG A C6 1 HETATM 4294 C C7 . NAG B 2 . ? -10.618 22.726 -7.334 1.00 37.67 ? 750 NAG A C7 1 HETATM 4295 C C8 . NAG B 2 . ? -11.936 22.187 -7.801 1.00 37.25 ? 750 NAG A C8 1 HETATM 4296 N N2 . NAG B 2 . ? -9.570 21.966 -7.666 1.00 37.09 ? 750 NAG A N2 1 HETATM 4297 O O3 . NAG B 2 . ? -7.773 23.515 -9.410 1.00 34.89 ? 750 NAG A O3 1 HETATM 4298 O O4 . NAG B 2 . ? -5.154 22.596 -9.473 1.00 43.51 ? 750 NAG A O4 1 HETATM 4299 O O5 . NAG B 2 . ? -6.262 21.512 -6.180 1.00 36.06 ? 750 NAG A O5 1 HETATM 4300 O O6 . NAG B 2 . ? -4.065 22.850 -5.682 1.00 38.76 ? 750 NAG A O6 1 HETATM 4301 O O7 . NAG B 2 . ? -10.563 23.796 -6.712 1.00 37.86 ? 750 NAG A O7 1 HETATM 4302 C C1 . NAG C 2 . ? -4.226 23.685 -9.532 1.00 47.36 ? 751 NAG A C1 1 HETATM 4303 C C2 . NAG C 2 . ? -3.107 23.261 -10.462 1.00 49.16 ? 751 NAG A C2 1 HETATM 4304 C C3 . NAG C 2 . ? -2.072 24.368 -10.556 1.00 51.16 ? 751 NAG A C3 1 HETATM 4305 C C4 . NAG C 2 . ? -2.724 25.698 -10.982 1.00 53.04 ? 751 NAG A C4 1 HETATM 4306 C C5 . NAG C 2 . ? -3.905 25.987 -10.047 1.00 51.59 ? 751 NAG A C5 1 HETATM 4307 C C6 . NAG C 2 . ? -4.657 27.251 -10.455 1.00 50.91 ? 751 NAG A C6 1 HETATM 4308 C C7 . NAG C 2 . ? -2.801 20.839 -10.653 1.00 48.94 ? 751 NAG A C7 1 HETATM 4309 C C8 . NAG C 2 . ? -2.101 19.616 -10.142 1.00 47.89 ? 751 NAG A C8 1 HETATM 4310 N N2 . NAG C 2 . ? -2.516 21.996 -10.043 1.00 49.38 ? 751 NAG A N2 1 HETATM 4311 O O3 . NAG C 2 . ? -1.187 23.922 -11.542 1.00 50.48 ? 751 NAG A O3 1 HETATM 4312 O O4 . NAG C 2 . ? -1.904 26.874 -10.978 1.00 57.34 ? 751 NAG A O4 1 HETATM 4313 O O5 . NAG C 2 . ? -4.800 24.883 -10.007 1.00 49.78 ? 751 NAG A O5 1 HETATM 4314 O O6 . NAG C 2 . ? -5.642 27.520 -9.482 1.00 51.41 ? 751 NAG A O6 1 HETATM 4315 O O7 . NAG C 2 . ? -3.599 20.742 -11.586 1.00 48.70 ? 751 NAG A O7 1 HETATM 4316 C C1 . MAN D 3 . ? -0.542 26.851 -11.478 1.00 60.20 ? 752 MAN A C1 1 HETATM 4317 C C2 . MAN D 3 . ? -0.358 25.840 -12.603 1.00 61.65 ? 752 MAN A C2 1 HETATM 4318 C C3 . MAN D 3 . ? 1.122 25.767 -12.958 1.00 63.39 ? 752 MAN A C3 1 HETATM 4319 C C4 . MAN D 3 . ? 1.565 27.116 -13.524 1.00 63.12 ? 752 MAN A C4 1 HETATM 4320 C C5 . MAN D 3 . ? 0.896 28.337 -12.860 1.00 62.65 ? 752 MAN A C5 1 HETATM 4321 C C6 . MAN D 3 . ? 0.286 29.203 -13.945 1.00 62.59 ? 752 MAN A C6 1 HETATM 4322 O O2 . MAN D 3 . ? -1.180 26.174 -13.698 1.00 62.98 ? 752 MAN A O2 1 HETATM 4323 O O3 . MAN D 3 . ? 1.423 24.654 -13.799 1.00 64.47 ? 752 MAN A O3 1 HETATM 4324 O O4 . MAN D 3 . ? 2.956 27.244 -13.343 1.00 64.52 ? 752 MAN A O4 1 HETATM 4325 O O5 . MAN D 3 . ? -0.100 28.154 -11.841 1.00 60.72 ? 752 MAN A O5 1 HETATM 4326 O O6 . MAN D 3 . ? 0.273 30.480 -13.378 1.00 63.35 ? 752 MAN A O6 1 HETATM 4327 C C1 . MAN E 3 . ? 0.298 31.456 -14.421 1.00 64.29 ? 753 MAN A C1 1 HETATM 4328 C C2 . MAN E 3 . ? 1.368 32.497 -14.137 1.00 64.75 ? 753 MAN A C2 1 HETATM 4329 C C3 . MAN E 3 . ? 1.085 33.195 -12.804 1.00 64.17 ? 753 MAN A C3 1 HETATM 4330 C C4 . MAN E 3 . ? -0.399 33.527 -12.561 1.00 64.79 ? 753 MAN A C4 1 HETATM 4331 C C5 . MAN E 3 . ? -1.380 32.541 -13.210 1.00 65.13 ? 753 MAN A C5 1 HETATM 4332 C C6 . MAN E 3 . ? -2.784 33.122 -13.351 1.00 65.28 ? 753 MAN A C6 1 HETATM 4333 O O2 . MAN E 3 . ? 1.354 33.466 -15.159 1.00 66.39 ? 753 MAN A O2 1 HETATM 4334 O O3 . MAN E 3 . ? 1.851 34.380 -12.742 1.00 63.51 ? 753 MAN A O3 1 HETATM 4335 O O4 . MAN E 3 . ? -0.658 33.544 -11.171 1.00 64.53 ? 753 MAN A O4 1 HETATM 4336 O O5 . MAN E 3 . ? -0.927 32.140 -14.490 1.00 65.19 ? 753 MAN A O5 1 HETATM 4337 O O6 . MAN E 3 . ? -3.659 32.093 -13.762 1.00 65.49 ? 753 MAN A O6 1 HETATM 4338 C C1 . MAN F 3 . ? 2.190 33.137 -16.286 1.00 67.89 ? 754 MAN A C1 1 HETATM 4339 C C2 . MAN F 3 . ? 2.939 34.406 -16.710 1.00 69.14 ? 754 MAN A C2 1 HETATM 4340 C C3 . MAN F 3 . ? 1.986 35.467 -17.289 1.00 69.89 ? 754 MAN A C3 1 HETATM 4341 C C4 . MAN F 3 . ? 0.934 34.875 -18.240 1.00 69.80 ? 754 MAN A C4 1 HETATM 4342 C C5 . MAN F 3 . ? 0.372 33.541 -17.728 1.00 69.26 ? 754 MAN A C5 1 HETATM 4343 C C6 . MAN F 3 . ? -0.587 32.919 -18.740 1.00 69.10 ? 754 MAN A C6 1 HETATM 4344 O O2 . MAN F 3 . ? 3.925 34.087 -17.667 1.00 69.84 ? 754 MAN A O2 1 HETATM 4345 O O3 . MAN F 3 . ? 2.708 36.482 -17.959 1.00 69.71 ? 754 MAN A O3 1 HETATM 4346 O O4 . MAN F 3 . ? -0.115 35.810 -18.394 1.00 70.16 ? 754 MAN A O4 1 HETATM 4347 O O5 . MAN F 3 . ? 1.429 32.650 -17.374 1.00 68.24 ? 754 MAN A O5 1 HETATM 4348 O O6 . MAN F 3 . ? -0.046 31.713 -19.221 1.00 69.85 ? 754 MAN A O6 1 HETATM 4349 C C1 . MAN G 3 . ? 1.749 23.529 -12.931 1.00 66.17 ? 755 MAN A C1 1 HETATM 4350 C C2 . MAN G 3 . ? 3.165 22.999 -13.181 1.00 66.29 ? 755 MAN A C2 1 HETATM 4351 C C3 . MAN G 3 . ? 3.149 21.475 -13.291 1.00 66.79 ? 755 MAN A C3 1 HETATM 4352 C C4 . MAN G 3 . ? 2.055 20.991 -14.263 1.00 66.48 ? 755 MAN A C4 1 HETATM 4353 C C5 . MAN G 3 . ? 0.671 21.517 -13.882 1.00 65.78 ? 755 MAN A C5 1 HETATM 4354 C C6 . MAN G 3 . ? -0.228 20.368 -13.431 1.00 64.97 ? 755 MAN A C6 1 HETATM 4355 O O2 . MAN G 3 . ? 3.998 23.394 -12.112 1.00 65.78 ? 755 MAN A O2 1 HETATM 4356 O O3 . MAN G 3 . ? 2.958 20.928 -11.995 1.00 66.37 ? 755 MAN A O3 1 HETATM 4357 O O4 . MAN G 3 . ? 2.339 21.406 -15.586 1.00 65.88 ? 755 MAN A O4 1 HETATM 4358 O O5 . MAN G 3 . ? 0.770 22.475 -12.835 1.00 66.48 ? 755 MAN A O5 1 HETATM 4359 O O6 . MAN G 3 . ? -1.039 19.935 -14.500 1.00 64.54 ? 755 MAN A O6 1 HETATM 4360 C C1 . NAG H 2 . ? -20.520 15.007 -23.899 1.00 65.94 ? 790 NAG A C1 1 HETATM 4361 C C2 . NAG H 2 . ? -19.677 15.126 -25.171 1.00 69.42 ? 790 NAG A C2 1 HETATM 4362 C C3 . NAG H 2 . ? -18.330 14.424 -25.032 1.00 70.48 ? 790 NAG A C3 1 HETATM 4363 C C4 . NAG H 2 . ? -17.600 14.761 -23.729 1.00 71.66 ? 790 NAG A C4 1 HETATM 4364 C C5 . NAG H 2 . ? -18.607 14.670 -22.567 1.00 70.09 ? 790 NAG A C5 1 HETATM 4365 C C6 . NAG H 2 . ? -18.010 14.968 -21.184 1.00 70.21 ? 790 NAG A C6 1 HETATM 4366 C C7 . NAG H 2 . ? -21.007 15.350 -27.194 1.00 70.66 ? 790 NAG A C7 1 HETATM 4367 C C8 . NAG H 2 . ? -21.316 14.737 -28.536 1.00 70.23 ? 790 NAG A C8 1 HETATM 4368 N N2 . NAG H 2 . ? -20.375 14.572 -26.317 1.00 70.17 ? 790 NAG A N2 1 HETATM 4369 O O3 . NAG H 2 . ? -17.554 14.827 -26.129 1.00 71.02 ? 790 NAG A O3 1 HETATM 4370 O O4 . NAG H 2 . ? -16.493 13.878 -23.561 1.00 74.92 ? 790 NAG A O4 1 HETATM 4371 O O5 . NAG H 2 . ? -19.739 15.497 -22.821 1.00 67.61 ? 790 NAG A O5 1 HETATM 4372 O O6 . NAG H 2 . ? -17.265 16.170 -21.167 1.00 69.97 ? 790 NAG A O6 1 HETATM 4373 O O7 . NAG H 2 . ? -21.332 16.511 -26.926 1.00 70.49 ? 790 NAG A O7 1 HETATM 4374 C C1 . NAG I 2 . ? -15.213 14.575 -23.491 1.00 77.63 ? 791 NAG A C1 1 HETATM 4375 C C2 . NAG I 2 . ? -14.124 13.650 -22.908 1.00 79.27 ? 791 NAG A C2 1 HETATM 4376 C C3 . NAG I 2 . ? -12.806 13.577 -23.708 1.00 80.05 ? 791 NAG A C3 1 HETATM 4377 C C4 . NAG I 2 . ? -12.897 13.774 -25.231 1.00 79.86 ? 791 NAG A C4 1 HETATM 4378 C C5 . NAG I 2 . ? -14.160 14.480 -25.723 1.00 79.55 ? 791 NAG A C5 1 HETATM 4379 C C6 . NAG I 2 . ? -15.050 13.459 -26.446 1.00 79.56 ? 791 NAG A C6 1 HETATM 4380 C C7 . NAG I 2 . ? -13.435 13.243 -20.556 1.00 81.46 ? 791 NAG A C7 1 HETATM 4381 C C8 . NAG I 2 . ? -11.968 13.220 -20.196 1.00 81.33 ? 791 NAG A C8 1 HETATM 4382 N N2 . NAG I 2 . ? -13.815 14.068 -21.544 1.00 80.57 ? 791 NAG A N2 1 HETATM 4383 O O3 . NAG I 2 . ? -12.201 12.317 -23.469 1.00 80.37 ? 791 NAG A O3 1 HETATM 4384 O O4 . NAG I 2 . ? -11.768 14.481 -25.703 1.00 80.20 ? 791 NAG A O4 1 HETATM 4385 O O5 . NAG I 2 . ? -14.815 15.234 -24.694 1.00 78.06 ? 791 NAG A O5 1 HETATM 4386 O O6 . NAG I 2 . ? -15.307 13.887 -27.766 1.00 79.67 ? 791 NAG A O6 1 HETATM 4387 O O7 . NAG I 2 . ? -14.234 12.533 -19.939 1.00 81.58 ? 791 NAG A O7 1 HETATM 4388 C C1 . NAG J 2 . ? -38.931 6.821 13.802 1.00 64.48 ? 770 NAG A C1 1 HETATM 4389 C C2 . NAG J 2 . ? -38.983 5.387 14.325 1.00 65.29 ? 770 NAG A C2 1 HETATM 4390 C C3 . NAG J 2 . ? -39.206 5.308 15.841 1.00 65.90 ? 770 NAG A C3 1 HETATM 4391 C C4 . NAG J 2 . ? -38.436 6.374 16.635 1.00 65.92 ? 770 NAG A C4 1 HETATM 4392 C C5 . NAG J 2 . ? -38.529 7.768 16.005 1.00 65.83 ? 770 NAG A C5 1 HETATM 4393 C C6 . NAG J 2 . ? -37.141 8.360 15.756 1.00 66.00 ? 770 NAG A C6 1 HETATM 4394 C C7 . NAG J 2 . ? -39.775 3.501 13.019 1.00 64.21 ? 770 NAG A C7 1 HETATM 4395 C C8 . NAG J 2 . ? -40.502 2.302 13.561 1.00 64.33 ? 770 NAG A C8 1 HETATM 4396 N N2 . NAG J 2 . ? -40.020 4.665 13.617 1.00 64.37 ? 770 NAG A N2 1 HETATM 4397 O O3 . NAG J 2 . ? -38.807 4.026 16.277 1.00 66.60 ? 770 NAG A O3 1 HETATM 4398 O O4 . NAG J 2 . ? -38.923 6.442 17.959 1.00 66.12 ? 770 NAG A O4 1 HETATM 4399 O O5 . NAG J 2 . ? -39.301 7.762 14.805 1.00 66.03 ? 770 NAG A O5 1 HETATM 4400 O O6 . NAG J 2 . ? -36.697 9.023 16.914 1.00 66.33 ? 770 NAG A O6 1 HETATM 4401 O O7 . NAG J 2 . ? -39.001 3.383 12.070 1.00 63.85 ? 770 NAG A O7 1 HETATM 4402 C C1 . SUC K 4 . ? -16.435 16.982 -9.976 1.00 40.44 ? 800 SUC A C1 1 HETATM 4403 C C2 . SUC K 4 . ? -15.444 17.651 -10.942 1.00 39.81 ? 800 SUC A C2 1 HETATM 4404 C C3 . SUC K 4 . ? -15.716 17.223 -12.390 1.00 40.21 ? 800 SUC A C3 1 HETATM 4405 C C4 . SUC K 4 . ? -15.775 15.698 -12.491 1.00 40.27 ? 800 SUC A C4 1 HETATM 4406 C C5 . SUC K 4 . ? -16.763 15.155 -11.463 1.00 40.64 ? 800 SUC A C5 1 HETATM 4407 C C6 . SUC K 4 . ? -16.862 13.636 -11.537 1.00 41.04 ? 800 SUC A C6 1 HETATM 4408 O O1 . SUC K 4 . ? -17.758 17.474 -10.199 1.00 40.36 ? 800 SUC A O1 1 HETATM 4409 O O2 . SUC K 4 . ? -15.562 19.048 -10.826 1.00 39.09 ? 800 SUC A O2 1 HETATM 4410 O O3 . SUC K 4 . ? -14.770 17.756 -13.295 1.00 39.68 ? 800 SUC A O3 1 HETATM 4411 O O4 . SUC K 4 . ? -16.202 15.279 -13.767 1.00 40.69 ? 800 SUC A O4 1 HETATM 4412 O O5 . SUC K 4 . ? -16.404 15.574 -10.149 1.00 40.57 ? 800 SUC A O5 1 HETATM 4413 O O6 . SUC K 4 . ? -15.617 13.070 -11.885 1.00 41.84 ? 800 SUC A O6 1 HETATM 4414 C "C1'" . SUC K 4 . ? -18.289 19.151 -8.542 1.00 40.38 ? 800 SUC A "C1'" 1 HETATM 4415 C "C2'" . SUC K 4 . ? -18.570 17.751 -9.067 1.00 39.37 ? 800 SUC A "C2'" 1 HETATM 4416 C "C3'" . SUC K 4 . ? -20.025 17.648 -9.468 1.00 38.48 ? 800 SUC A "C3'" 1 HETATM 4417 C "C4'" . SUC K 4 . ? -20.331 16.192 -9.286 1.00 37.80 ? 800 SUC A "C4'" 1 HETATM 4418 C "C5'" . SUC K 4 . ? -19.462 15.835 -8.088 1.00 38.32 ? 800 SUC A "C5'" 1 HETATM 4419 C "C6'" . SUC K 4 . ? -18.889 14.421 -8.132 1.00 37.99 ? 800 SUC A "C6'" 1 HETATM 4420 O "O1'" . SUC K 4 . ? -17.234 19.072 -7.609 1.00 43.33 ? 800 SUC A "O1'" 1 HETATM 4421 O "O2'" . SUC K 4 . ? -18.400 16.773 -8.060 1.00 38.35 ? 800 SUC A "O2'" 1 HETATM 4422 O "O3'" . SUC K 4 . ? -20.221 18.015 -10.804 1.00 39.56 ? 800 SUC A "O3'" 1 HETATM 4423 O "O4'" . SUC K 4 . ? -21.708 16.053 -9.048 1.00 36.74 ? 800 SUC A "O4'" 1 HETATM 4424 O "O6'" . SUC K 4 . ? -18.179 14.194 -6.930 1.00 38.01 ? 800 SUC A "O6'" 1 HETATM 4425 ZN ZN . ZN L 5 . ? -9.389 62.792 -1.286 1.00 65.71 ? 1101 ZN A ZN 1 HETATM 4426 ZN ZN . ZN M 5 . ? -24.576 34.728 -18.728 1.00 71.00 ? 1102 ZN A ZN 1 HETATM 4427 ZN ZN . ZN N 5 . ? -8.132 30.634 -12.946 1.00 75.69 ? 1103 ZN A ZN 1 HETATM 4428 ZN ZN . ZN O 5 . ? -23.711 17.918 18.869 1.00 83.92 ? 1104 ZN A ZN 1 HETATM 4429 O O . HOH P 6 . ? -11.433 48.926 -5.822 1.00 20.39 ? 1001 HOH A O 1 HETATM 4430 O O . HOH P 6 . ? -4.377 27.528 -6.700 1.00 31.30 ? 1002 HOH A O 1 HETATM 4431 O O . HOH P 6 . ? -32.379 27.342 -1.562 1.00 28.90 ? 1003 HOH A O 1 HETATM 4432 O O . HOH P 6 . ? -45.584 40.535 -6.086 1.00 59.29 ? 1004 HOH A O 1 HETATM 4433 O O . HOH P 6 . ? -21.936 49.534 -0.920 1.00 32.32 ? 1005 HOH A O 1 HETATM 4434 O O . HOH P 6 . ? -18.491 24.360 9.653 1.00 30.49 ? 1006 HOH A O 1 HETATM 4435 O O . HOH P 6 . ? -1.841 28.741 -3.363 1.00 31.07 ? 1007 HOH A O 1 HETATM 4436 O O . HOH P 6 . ? -6.594 58.873 7.091 1.00 38.72 ? 1008 HOH A O 1 HETATM 4437 O O . HOH P 6 . ? 2.259 56.575 -10.005 1.00 30.89 ? 1009 HOH A O 1 HETATM 4438 O O . HOH P 6 . ? -15.724 31.508 -6.070 1.00 34.51 ? 1010 HOH A O 1 HETATM 4439 O O . HOH P 6 . ? -29.489 21.715 -0.600 1.00 36.71 ? 1011 HOH A O 1 HETATM 4440 O O . HOH P 6 . ? -12.071 31.213 -7.210 1.00 37.52 ? 1012 HOH A O 1 HETATM 4441 O O . HOH P 6 . ? -17.917 39.404 -1.162 1.00 29.93 ? 1013 HOH A O 1 HETATM 4442 O O . HOH P 6 . ? -32.848 25.884 0.996 1.00 15.80 ? 1014 HOH A O 1 HETATM 4443 O O . HOH P 6 . ? -33.619 19.921 -4.471 1.00 40.19 ? 1015 HOH A O 1 HETATM 4444 O O . HOH P 6 . ? -30.982 38.740 1.087 1.00 33.16 ? 1016 HOH A O 1 HETATM 4445 O O . HOH P 6 . ? -15.842 31.767 5.782 1.00 29.57 ? 1017 HOH A O 1 HETATM 4446 O O . HOH P 6 . ? -24.684 35.089 10.909 1.00 4.75 ? 1018 HOH A O 1 HETATM 4447 O O . HOH P 6 . ? -16.433 24.347 8.008 1.00 24.55 ? 1019 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ASN 1 5 5 ASN ASN A . n A 1 2 GLN 2 6 6 GLN GLN A . n A 1 3 PRO 3 7 7 PRO PRO A . n A 1 4 TYR 4 8 8 TYR TYR A . n A 1 5 ARG 5 9 9 ARG ARG A . n A 1 6 THR 6 10 10 THR THR A . n A 1 7 GLY 7 11 11 GLY GLY A . n A 1 8 PHE 8 12 12 PHE PHE A . n A 1 9 HIS 9 13 13 HIS HIS A . n A 1 10 PHE 10 14 14 PHE PHE A . n A 1 11 GLN 11 15 15 GLN GLN A . n A 1 12 PRO 12 16 16 PRO PRO A . n A 1 13 PRO 13 17 17 PRO PRO A . n A 1 14 LYS 14 18 18 LYS LYS A . n A 1 15 ASN 15 19 19 ASN ASN A . n A 1 16 TRP 16 20 20 TRP TRP A . n A 1 17 MET 17 21 21 MET MET A . n A 1 18 ASN 18 22 22 ASN ASN A . n A 1 19 ALA 19 23 23 ALA ALA A . n A 1 20 PRO 20 24 24 PRO PRO A . n A 1 21 ASN 21 25 25 ASN ASN A . n A 1 22 GLY 22 26 26 GLY GLY A . n A 1 23 PRO 23 27 27 PRO PRO A . n A 1 24 MET 24 28 28 MET MET A . n A 1 25 ILE 25 29 29 ILE ILE A . n A 1 26 TYR 26 30 30 TYR TYR A . n A 1 27 LYS 27 31 31 LYS LYS A . n A 1 28 GLY 28 32 32 GLY GLY A . n A 1 29 ILE 29 33 33 ILE ILE A . n A 1 30 TYR 30 34 34 TYR TYR A . n A 1 31 HIS 31 35 35 HIS HIS A . n A 1 32 LEU 32 36 36 LEU LEU A . n A 1 33 PHE 33 37 37 PHE PHE A . n A 1 34 TYR 34 38 38 TYR TYR A . n A 1 35 GLN 35 39 39 GLN GLN A . n A 1 36 TRP 36 40 40 TRP TRP A . n A 1 37 ASN 37 41 41 ASN ASN A . n A 1 38 PRO 38 42 42 PRO PRO A . n A 1 39 LYS 39 43 43 LYS LYS A . n A 1 40 GLY 40 44 44 GLY GLY A . n A 1 41 ALA 41 45 45 ALA ALA A . n A 1 42 VAL 42 46 46 VAL VAL A . n A 1 43 TRP 43 47 47 TRP TRP A . n A 1 44 GLY 44 48 48 GLY GLY A . n A 1 45 ASN 45 49 49 ASN ASN A . n A 1 46 ILE 46 50 50 ILE ILE A . n A 1 47 VAL 47 51 51 VAL VAL A . n A 1 48 TRP 48 52 52 TRP TRP A . n A 1 49 ALA 49 53 53 ALA ALA A . n A 1 50 HIS 50 54 54 HIS HIS A . n A 1 51 SER 51 55 55 SER SER A . n A 1 52 THR 52 56 56 THR THR A . n A 1 53 SER 53 57 57 SER SER A . n A 1 54 THR 54 58 58 THR THR A . n A 1 55 ASP 55 59 59 ASP ASP A . n A 1 56 LEU 56 60 60 LEU LEU A . n A 1 57 ILE 57 61 61 ILE ILE A . n A 1 58 ASN 58 62 62 ASN ASN A . n A 1 59 TRP 59 63 63 TRP TRP A . n A 1 60 ASP 60 64 64 ASP ASP A . n A 1 61 PRO 61 65 65 PRO PRO A . n A 1 62 HIS 62 66 66 HIS HIS A . n A 1 63 PRO 63 67 67 PRO PRO A . n A 1 64 PRO 64 68 68 PRO PRO A . n A 1 65 ALA 65 69 69 ALA ALA A . n A 1 66 ILE 66 70 70 ILE ILE A . n A 1 67 PHE 67 71 71 PHE PHE A . n A 1 68 PRO 68 72 72 PRO PRO A . n A 1 69 SER 69 73 73 SER SER A . n A 1 70 ALA 70 74 74 ALA ALA A . n A 1 71 PRO 71 75 75 PRO PRO A . n A 1 72 PHE 72 76 76 PHE PHE A . n A 1 73 ASP 73 77 77 ASP ASP A . n A 1 74 ILE 74 78 78 ILE ILE A . n A 1 75 ASN 75 79 79 ASN ASN A . n A 1 76 GLY 76 80 80 GLY GLY A . n A 1 77 CYS 77 81 81 CYS CYS A . n A 1 78 TRP 78 82 82 TRP TRP A . n A 1 79 SER 79 83 83 SER SER A . n A 1 80 GLY 80 84 84 GLY GLY A . n A 1 81 SER 81 85 85 SER SER A . n A 1 82 ALA 82 86 86 ALA ALA A . n A 1 83 THR 83 87 87 THR THR A . n A 1 84 ILE 84 88 88 ILE ILE A . n A 1 85 LEU 85 89 89 LEU LEU A . n A 1 86 PRO 86 90 90 PRO PRO A . n A 1 87 ASN 87 91 91 ASN ASN A . n A 1 88 GLY 88 92 92 GLY GLY A . n A 1 89 LYS 89 93 93 LYS LYS A . n A 1 90 PRO 90 94 94 PRO PRO A . n A 1 91 VAL 91 95 95 VAL VAL A . n A 1 92 ILE 92 96 96 ILE ILE A . n A 1 93 LEU 93 97 97 LEU LEU A . n A 1 94 TYR 94 98 98 TYR TYR A . n A 1 95 THR 95 99 99 THR THR A . n A 1 96 GLY 96 100 100 GLY GLY A . n A 1 97 ILE 97 101 101 ILE ILE A . n A 1 98 ASP 98 102 102 ASP ASP A . n A 1 99 PRO 99 103 103 PRO PRO A . n A 1 100 LYS 100 104 104 LYS LYS A . n A 1 101 ASN 101 105 105 ASN ASN A . n A 1 102 GLN 102 106 106 GLN GLN A . n A 1 103 GLN 103 107 107 GLN GLN A . n A 1 104 VAL 104 108 108 VAL VAL A . n A 1 105 GLN 105 109 109 GLN GLN A . n A 1 106 ASN 106 110 110 ASN ASN A . n A 1 107 ILE 107 111 111 ILE ILE A . n A 1 108 ALA 108 112 112 ALA ALA A . n A 1 109 GLU 109 113 113 GLU GLU A . n A 1 110 PRO 110 114 114 PRO PRO A . n A 1 111 LYS 111 115 115 LYS LYS A . n A 1 112 ASN 112 116 116 ASN ASN A . n A 1 113 LEU 113 117 117 LEU LEU A . n A 1 114 SER 114 118 118 SER SER A . n A 1 115 ASP 115 119 119 ASP ASP A . n A 1 116 PRO 116 120 120 PRO PRO A . n A 1 117 TYR 117 121 121 TYR TYR A . n A 1 118 LEU 118 122 122 LEU LEU A . n A 1 119 ARG 119 123 123 ARG ARG A . n A 1 120 GLU 120 124 124 GLU GLU A . n A 1 121 TRP 121 125 125 TRP TRP A . n A 1 122 LYS 122 126 126 LYS LYS A . n A 1 123 LYS 123 127 127 LYS LYS A . n A 1 124 SER 124 128 128 SER SER A . n A 1 125 PRO 125 129 129 PRO PRO A . n A 1 126 LEU 126 130 130 LEU LEU A . n A 1 127 ASN 127 131 131 ASN ASN A . n A 1 128 PRO 128 132 132 PRO PRO A . n A 1 129 LEU 129 133 133 LEU LEU A . n A 1 130 MET 130 134 134 MET MET A . n A 1 131 ALA 131 135 135 ALA ALA A . n A 1 132 PRO 132 136 136 PRO PRO A . n A 1 133 ASP 133 137 137 ASP ASP A . n A 1 134 ALA 134 138 138 ALA ALA A . n A 1 135 VAL 135 139 139 VAL VAL A . n A 1 136 ASN 136 140 140 ASN ASN A . n A 1 137 GLY 137 141 141 GLY GLY A . n A 1 138 ILE 138 142 142 ILE ILE A . n A 1 139 ASN 139 143 143 ASN ASN A . n A 1 140 ALA 140 144 144 ALA ALA A . n A 1 141 SER 141 145 145 SER SER A . n A 1 142 SER 142 146 146 SER SER A . n A 1 143 PHE 143 147 147 PHE PHE A . n A 1 144 ARG 144 148 148 ARG ARG A . n A 1 145 ASP 145 149 149 ASP ASP A . n A 1 146 PRO 146 150 150 PRO PRO A . n A 1 147 THR 147 151 151 THR THR A . n A 1 148 THR 148 152 152 THR THR A . n A 1 149 ALA 149 153 153 ALA ALA A . n A 1 150 TRP 150 154 154 TRP TRP A . n A 1 151 LEU 151 155 155 LEU LEU A . n A 1 152 GLY 152 156 156 GLY GLY A . n A 1 153 GLN 153 157 157 GLN GLN A . n A 1 154 ASP 154 158 158 ASP ASP A . n A 1 155 LYS 155 159 159 LYS LYS A . n A 1 156 LYS 156 160 160 LYS LYS A . n A 1 157 TRP 157 161 161 TRP TRP A . n A 1 158 ARG 158 162 162 ARG ARG A . n A 1 159 VAL 159 163 163 VAL VAL A . n A 1 160 ILE 160 164 164 ILE ILE A . n A 1 161 ILE 161 165 165 ILE ILE A . n A 1 162 GLY 162 166 166 GLY GLY A . n A 1 163 SER 163 167 167 SER SER A . n A 1 164 LYS 164 168 168 LYS LYS A . n A 1 165 ILE 165 169 169 ILE ILE A . n A 1 166 HIS 166 170 170 HIS HIS A . n A 1 167 ARG 167 171 171 ARG ARG A . n A 1 168 ARG 168 172 172 ARG ARG A . n A 1 169 GLY 169 173 173 GLY GLY A . n A 1 170 LEU 170 174 174 LEU LEU A . n A 1 171 ALA 171 175 175 ALA ALA A . n A 1 172 ILE 172 176 176 ILE ILE A . n A 1 173 THR 173 177 177 THR THR A . n A 1 174 TYR 174 178 178 TYR TYR A . n A 1 175 THR 175 179 179 THR THR A . n A 1 176 SER 176 180 180 SER SER A . n A 1 177 LYS 177 181 181 LYS LYS A . n A 1 178 ASP 178 182 182 ASP ASP A . n A 1 179 PHE 179 183 183 PHE PHE A . n A 1 180 LEU 180 184 184 LEU LEU A . n A 1 181 LYS 181 185 185 LYS LYS A . n A 1 182 TRP 182 186 186 TRP TRP A . n A 1 183 GLU 183 187 187 GLU GLU A . n A 1 184 LYS 184 188 188 LYS LYS A . n A 1 185 SER 185 189 189 SER SER A . n A 1 186 PRO 186 190 190 PRO PRO A . n A 1 187 GLU 187 191 191 GLU GLU A . n A 1 188 PRO 188 192 192 PRO PRO A . n A 1 189 LEU 189 193 193 LEU LEU A . n A 1 190 HIS 190 194 194 HIS HIS A . n A 1 191 TYR 191 195 195 TYR TYR A . n A 1 192 ASP 192 196 196 ASP ASP A . n A 1 193 ASP 193 197 197 ASP ASP A . n A 1 194 GLY 194 198 198 GLY GLY A . n A 1 195 SER 195 199 199 SER SER A . n A 1 196 GLY 196 200 200 GLY GLY A . n A 1 197 MET 197 201 201 MET MET A . n A 1 198 TRP 198 202 202 TRP TRP A . n A 1 199 GLU 199 203 203 GLU GLU A . n A 1 200 CYS 200 204 204 CYS CYS A . n A 1 201 PRO 201 205 205 PRO PRO A . n A 1 202 ASP 202 206 206 ASP ASP A . n A 1 203 PHE 203 207 207 PHE PHE A . n A 1 204 PHE 204 208 208 PHE PHE A . n A 1 205 PRO 205 209 209 PRO PRO A . n A 1 206 VAL 206 210 210 VAL VAL A . n A 1 207 THR 207 211 211 THR THR A . n A 1 208 ARG 208 212 212 ARG ARG A . n A 1 209 PHE 209 213 213 PHE PHE A . n A 1 210 GLY 210 214 214 GLY GLY A . n A 1 211 SER 211 215 215 SER SER A . n A 1 212 ASN 212 216 216 ASN ASN A . n A 1 213 GLY 213 217 217 GLY GLY A . n A 1 214 VAL 214 218 218 VAL VAL A . n A 1 215 GLU 215 219 219 GLU GLU A . n A 1 216 THR 216 220 220 THR THR A . n A 1 217 SER 217 221 221 SER SER A . n A 1 218 SER 218 222 222 SER SER A . n A 1 219 PHE 219 223 223 PHE PHE A . n A 1 220 GLY 220 224 224 GLY GLY A . n A 1 221 GLU 221 225 225 GLU GLU A . n A 1 222 PRO 222 226 226 PRO PRO A . n A 1 223 ASN 223 227 227 ASN ASN A . n A 1 224 GLU 224 228 228 GLU GLU A . n A 1 225 ILE 225 229 229 ILE ILE A . n A 1 226 LEU 226 230 230 LEU LEU A . n A 1 227 LYS 227 231 231 LYS LYS A . n A 1 228 HIS 228 232 232 HIS HIS A . n A 1 229 VAL 229 233 233 VAL VAL A . n A 1 230 LEU 230 234 234 LEU LEU A . n A 1 231 LYS 231 235 235 LYS LYS A . n A 1 232 ILE 232 236 236 ILE ILE A . n A 1 233 SER 233 237 237 SER SER A . n A 1 234 LEU 234 238 238 LEU LEU A . n A 1 235 ASP 235 239 239 ASP ASP A . n A 1 236 ASP 236 240 240 ASP ASP A . n A 1 237 THR 237 241 241 THR THR A . n A 1 238 LYS 238 242 242 LYS LYS A . n A 1 239 HIS 239 243 243 HIS HIS A . n A 1 240 ASP 240 244 244 ASP ASP A . n A 1 241 TYR 241 245 245 TYR TYR A . n A 1 242 TYR 242 246 246 TYR TYR A . n A 1 243 THR 243 247 247 THR THR A . n A 1 244 ILE 244 248 248 ILE ILE A . n A 1 245 GLY 245 249 249 GLY GLY A . n A 1 246 THR 246 250 250 THR THR A . n A 1 247 TYR 247 251 251 TYR TYR A . n A 1 248 ASP 248 252 252 ASP ASP A . n A 1 249 ARG 249 253 253 ARG ARG A . n A 1 250 VAL 250 254 254 VAL VAL A . n A 1 251 LYS 251 255 255 LYS LYS A . n A 1 252 ASP 252 256 256 ASP ASP A . n A 1 253 LYS 253 257 257 LYS LYS A . n A 1 254 PHE 254 258 258 PHE PHE A . n A 1 255 VAL 255 259 259 VAL VAL A . n A 1 256 PRO 256 260 260 PRO PRO A . n A 1 257 ASP 257 261 261 ASP ASP A . n A 1 258 ASN 258 262 262 ASN ASN A . n A 1 259 GLY 259 263 263 GLY GLY A . n A 1 260 PHE 260 264 264 PHE PHE A . n A 1 261 LYS 261 265 ? ? ? A . n A 1 262 MET 262 266 ? ? ? A . n A 1 263 ASP 263 267 ? ? ? A . n A 1 264 GLY 264 268 268 GLY GLY A . n A 1 265 THR 265 269 269 THR THR A . n A 1 266 ALA 266 270 270 ALA ALA A . n A 1 267 PRO 267 271 271 PRO PRO A . n A 1 268 ARG 268 272 272 ARG ARG A . n A 1 269 TYR 269 273 273 TYR TYR A . n A 1 270 ASP 270 274 274 ASP ASP A . n A 1 271 TYR 271 275 275 TYR TYR A . n A 1 272 GLY 272 276 276 GLY GLY A . n A 1 273 LYS 273 277 277 LYS LYS A . n A 1 274 TYR 274 278 278 TYR TYR A . n A 1 275 TYR 275 279 279 TYR TYR A . n A 1 276 ALA 276 280 280 ALA ALA A . n A 1 277 SER 277 281 281 SER SER A . n A 1 278 LYS 278 282 282 LYS LYS A . n A 1 279 THR 279 283 283 THR THR A . n A 1 280 PHE 280 284 284 PHE PHE A . n A 1 281 PHE 281 285 285 PHE PHE A . n A 1 282 ASP 282 286 286 ASP ASP A . n A 1 283 SER 283 287 287 SER SER A . n A 1 284 ALA 284 288 288 ALA ALA A . n A 1 285 LYS 285 289 289 LYS LYS A . n A 1 286 ASN 286 290 290 ASN ASN A . n A 1 287 ARG 287 291 291 ARG ARG A . n A 1 288 ARG 288 292 292 ARG ARG A . n A 1 289 ILE 289 293 293 ILE ILE A . n A 1 290 LEU 290 294 294 LEU LEU A . n A 1 291 TRP 291 295 295 TRP TRP A . n A 1 292 GLY 292 296 296 GLY GLY A . n A 1 293 TRP 293 297 297 TRP TRP A . n A 1 294 THR 294 298 298 THR THR A . n A 1 295 ASN 295 299 299 ASN ASN A . n A 1 296 GLU 296 300 300 GLU GLU A . n A 1 297 SER 297 301 301 SER SER A . n A 1 298 SER 298 302 302 SER SER A . n A 1 299 SER 299 303 303 SER SER A . n A 1 300 VAL 300 304 304 VAL VAL A . n A 1 301 GLU 301 305 305 GLU GLU A . n A 1 302 ASP 302 306 306 ASP ASP A . n A 1 303 ASP 303 307 307 ASP ASP A . n A 1 304 VAL 304 308 308 VAL VAL A . n A 1 305 GLU 305 309 309 GLU GLU A . n A 1 306 LYS 306 310 310 LYS LYS A . n A 1 307 GLY 307 311 311 GLY GLY A . n A 1 308 TRP 308 312 312 TRP TRP A . n A 1 309 SER 309 313 313 SER SER A . n A 1 310 GLY 310 314 314 GLY GLY A . n A 1 311 ILE 311 315 315 ILE ILE A . n A 1 312 GLN 312 316 316 GLN GLN A . n A 1 313 THR 313 317 317 THR THR A . n A 1 314 ILE 314 318 318 ILE ILE A . n A 1 315 PRO 315 319 319 PRO PRO A . n A 1 316 ARG 316 320 320 ARG ARG A . n A 1 317 LYS 317 321 321 LYS LYS A . n A 1 318 ILE 318 322 322 ILE ILE A . n A 1 319 TRP 319 323 323 TRP TRP A . n A 1 320 LEU 320 324 324 LEU LEU A . n A 1 321 ASP 321 325 325 ASP ASP A . n A 1 322 ARG 322 326 326 ARG ARG A . n A 1 323 SER 323 327 327 SER SER A . n A 1 324 GLY 324 328 328 GLY GLY A . n A 1 325 LYS 325 329 329 LYS LYS A . n A 1 326 GLN 326 330 330 GLN GLN A . n A 1 327 LEU 327 331 331 LEU LEU A . n A 1 328 ILE 328 332 332 ILE ILE A . n A 1 329 GLN 329 333 333 GLN GLN A . n A 1 330 TRP 330 334 334 TRP TRP A . n A 1 331 PRO 331 335 335 PRO PRO A . n A 1 332 VAL 332 336 336 VAL VAL A . n A 1 333 ARG 333 337 337 ARG ARG A . n A 1 334 GLU 334 338 338 GLU GLU A . n A 1 335 VAL 335 339 339 VAL VAL A . n A 1 336 GLU 336 340 340 GLU GLU A . n A 1 337 ARG 337 341 341 ARG ARG A . n A 1 338 LEU 338 342 342 LEU LEU A . n A 1 339 ARG 339 343 343 ARG ARG A . n A 1 340 THR 340 344 344 THR THR A . n A 1 341 LYS 341 345 345 LYS LYS A . n A 1 342 GLN 342 346 346 GLN GLN A . n A 1 343 VAL 343 347 347 VAL VAL A . n A 1 344 LYS 344 348 348 LYS LYS A . n A 1 345 ASN 345 349 349 ASN ASN A . n A 1 346 LEU 346 350 350 LEU LEU A . n A 1 347 ARG 347 351 351 ARG ARG A . n A 1 348 ASN 348 352 352 ASN ASN A . n A 1 349 LYS 349 353 353 LYS LYS A . n A 1 350 VAL 350 354 354 VAL VAL A . n A 1 351 LEU 351 355 355 LEU LEU A . n A 1 352 LYS 352 356 356 LYS LYS A . n A 1 353 SER 353 357 357 SER SER A . n A 1 354 GLY 354 358 358 GLY GLY A . n A 1 355 SER 355 359 359 SER SER A . n A 1 356 ARG 356 360 360 ARG ARG A . n A 1 357 LEU 357 361 361 LEU LEU A . n A 1 358 GLU 358 362 362 GLU GLU A . n A 1 359 VAL 359 363 363 VAL VAL A . n A 1 360 TYR 360 364 364 TYR TYR A . n A 1 361 GLY 361 365 365 GLY GLY A . n A 1 362 VAL 362 366 366 VAL VAL A . n A 1 363 THR 363 367 367 THR THR A . n A 1 364 ALA 364 368 368 ALA ALA A . n A 1 365 ALA 365 369 369 ALA ALA A . n A 1 366 GLN 366 370 370 GLN GLN A . n A 1 367 ALA 367 371 371 ALA ALA A . n A 1 368 ASP 368 372 372 ASP ASP A . n A 1 369 VAL 369 373 373 VAL VAL A . n A 1 370 GLU 370 374 374 GLU GLU A . n A 1 371 VAL 371 375 375 VAL VAL A . n A 1 372 LEU 372 376 376 LEU LEU A . n A 1 373 PHE 373 377 377 PHE PHE A . n A 1 374 LYS 374 378 378 LYS LYS A . n A 1 375 VAL 375 379 379 VAL VAL A . n A 1 376 ARG 376 380 380 ARG ARG A . n A 1 377 ASP 377 381 381 ASP ASP A . n A 1 378 LEU 378 382 382 LEU LEU A . n A 1 379 GLU 379 383 383 GLU GLU A . n A 1 380 LYS 380 384 384 LYS LYS A . n A 1 381 ALA 381 385 385 ALA ALA A . n A 1 382 ASP 382 386 386 ASP ASP A . n A 1 383 VAL 383 387 387 VAL VAL A . n A 1 384 ILE 384 388 388 ILE ILE A . n A 1 385 GLU 385 389 389 GLU GLU A . n A 1 386 PRO 386 390 390 PRO PRO A . n A 1 387 SER 387 391 391 SER SER A . n A 1 388 TRP 388 392 392 TRP TRP A . n A 1 389 THR 389 393 393 THR THR A . n A 1 390 ASP 390 394 394 ASP ASP A . n A 1 391 PRO 391 395 395 PRO PRO A . n A 1 392 GLN 392 396 396 GLN GLN A . n A 1 393 LEU 393 397 397 LEU LEU A . n A 1 394 ILE 394 398 398 ILE ILE A . n A 1 395 CYS 395 399 399 CYS CYS A . n A 1 396 SER 396 400 400 SER SER A . n A 1 397 LYS 397 401 401 LYS LYS A . n A 1 398 MET 398 402 402 MET MET A . n A 1 399 ASN 399 403 403 ASN ASN A . n A 1 400 VAL 400 404 404 VAL VAL A . n A 1 401 SER 401 405 405 SER SER A . n A 1 402 VAL 402 406 406 VAL VAL A . n A 1 403 LYS 403 407 407 LYS LYS A . n A 1 404 SER 404 408 408 SER SER A . n A 1 405 GLY 405 409 409 GLY GLY A . n A 1 406 LEU 406 410 410 LEU LEU A . n A 1 407 GLY 407 411 411 GLY GLY A . n A 1 408 PRO 408 412 412 PRO PRO A . n A 1 409 PHE 409 413 413 PHE PHE A . n A 1 410 GLY 410 414 414 GLY GLY A . n A 1 411 LEU 411 415 415 LEU LEU A . n A 1 412 MET 412 416 416 MET MET A . n A 1 413 VAL 413 417 417 VAL VAL A . n A 1 414 LEU 414 418 418 LEU LEU A . n A 1 415 ALA 415 419 419 ALA ALA A . n A 1 416 SER 416 420 420 SER SER A . n A 1 417 LYS 417 421 421 LYS LYS A . n A 1 418 ASN 418 422 422 ASN ASN A . n A 1 419 LEU 419 423 423 LEU LEU A . n A 1 420 GLU 420 424 424 GLU GLU A . n A 1 421 GLU 421 425 425 GLU GLU A . n A 1 422 TYR 422 426 426 TYR TYR A . n A 1 423 THR 423 427 427 THR THR A . n A 1 424 SER 424 428 428 SER SER A . n A 1 425 VAL 425 429 429 VAL VAL A . n A 1 426 TYR 426 430 430 TYR TYR A . n A 1 427 PHE 427 431 431 PHE PHE A . n A 1 428 ARG 428 432 432 ARG ARG A . n A 1 429 ILE 429 433 433 ILE ILE A . n A 1 430 PHE 430 434 434 PHE PHE A . n A 1 431 LYS 431 435 435 LYS LYS A . n A 1 432 ALA 432 436 436 ALA ALA A . n A 1 433 ARG 433 437 437 ARG ARG A . n A 1 434 GLN 434 438 438 GLN GLN A . n A 1 435 ASN 435 439 439 ASN ASN A . n A 1 436 SER 436 440 440 SER SER A . n A 1 437 ASN 437 441 441 ASN ASN A . n A 1 438 LYS 438 442 442 LYS LYS A . n A 1 439 TYR 439 443 443 TYR TYR A . n A 1 440 VAL 440 444 444 VAL VAL A . n A 1 441 VAL 441 445 445 VAL VAL A . n A 1 442 LEU 442 446 446 LEU LEU A . n A 1 443 MET 443 447 447 MET MET A . n A 1 444 CYS 444 448 448 CYS CYS A . n A 1 445 SER 445 449 449 SER SER A . n A 1 446 ASP 446 450 450 ASP ASP A . n A 1 447 GLN 447 451 451 GLN GLN A . n A 1 448 SER 448 452 452 SER SER A . n A 1 449 ARG 449 453 453 ARG ARG A . n A 1 450 SER 450 454 454 SER SER A . n A 1 451 SER 451 455 455 SER SER A . n A 1 452 LEU 452 456 456 LEU LEU A . n A 1 453 LYS 453 457 457 LYS LYS A . n A 1 454 GLU 454 458 458 GLU GLU A . n A 1 455 ASP 455 459 459 ASP ASP A . n A 1 456 ASN 456 460 460 ASN ASN A . n A 1 457 ASP 457 461 461 ASP ASP A . n A 1 458 LYS 458 462 462 LYS LYS A . n A 1 459 THR 459 463 463 THR THR A . n A 1 460 THR 460 464 464 THR THR A . n A 1 461 TYR 461 465 465 TYR TYR A . n A 1 462 GLY 462 466 466 GLY GLY A . n A 1 463 ALA 463 467 467 ALA ALA A . n A 1 464 PHE 464 468 468 PHE PHE A . n A 1 465 VAL 465 469 469 VAL VAL A . n A 1 466 ASP 466 470 470 ASP ASP A . n A 1 467 ILE 467 471 471 ILE ILE A . n A 1 468 ASN 468 472 472 ASN ASN A . n A 1 469 PRO 469 473 473 PRO PRO A . n A 1 470 HIS 470 474 474 HIS HIS A . n A 1 471 GLN 471 475 475 GLN GLN A . n A 1 472 PRO 472 476 476 PRO PRO A . n A 1 473 LEU 473 477 477 LEU LEU A . n A 1 474 SER 474 478 478 SER SER A . n A 1 475 LEU 475 479 479 LEU LEU A . n A 1 476 ARG 476 480 480 ARG ARG A . n A 1 477 ALA 477 481 481 ALA ALA A . n A 1 478 LEU 478 482 482 LEU LEU A . n A 1 479 ILE 479 483 483 ILE ILE A . n A 1 480 ASP 480 484 484 ASP ASP A . n A 1 481 HIS 481 485 485 HIS HIS A . n A 1 482 SER 482 486 486 SER SER A . n A 1 483 VAL 483 487 487 VAL VAL A . n A 1 484 VAL 484 488 488 VAL VAL A . n A 1 485 GLU 485 489 489 GLU GLU A . n A 1 486 SER 486 490 490 SER SER A . n A 1 487 PHE 487 491 491 PHE PHE A . n A 1 488 GLY 488 492 492 GLY GLY A . n A 1 489 GLY 489 493 493 GLY GLY A . n A 1 490 LYS 490 494 494 LYS LYS A . n A 1 491 GLY 491 495 495 GLY GLY A . n A 1 492 ARG 492 496 496 ARG ARG A . n A 1 493 ALA 493 497 497 ALA ALA A . n A 1 494 CYS 494 498 498 CYS CYS A . n A 1 495 ILE 495 499 499 ILE ILE A . n A 1 496 THR 496 500 500 THR THR A . n A 1 497 SER 497 501 501 SER SER A . n A 1 498 ARG 498 502 502 ARG ARG A . n A 1 499 VAL 499 503 503 VAL VAL A . n A 1 500 TYR 500 504 504 TYR TYR A . n A 1 501 PRO 501 505 505 PRO PRO A . n A 1 502 LYS 502 506 506 LYS LYS A . n A 1 503 LEU 503 507 507 LEU LEU A . n A 1 504 ALA 504 508 508 ALA ALA A . n A 1 505 ILE 505 509 509 ILE ILE A . n A 1 506 GLY 506 510 510 GLY GLY A . n A 1 507 LYS 507 511 511 LYS LYS A . n A 1 508 SER 508 512 512 SER SER A . n A 1 509 SER 509 513 513 SER SER A . n A 1 510 HIS 510 514 514 HIS HIS A . n A 1 511 LEU 511 515 515 LEU LEU A . n A 1 512 PHE 512 516 516 PHE PHE A . n A 1 513 ALA 513 517 517 ALA ALA A . n A 1 514 PHE 514 518 518 PHE PHE A . n A 1 515 ASN 515 519 519 ASN ASN A . n A 1 516 TYR 516 520 520 TYR TYR A . n A 1 517 GLY 517 521 521 GLY GLY A . n A 1 518 TYR 518 522 522 TYR TYR A . n A 1 519 GLN 519 523 523 GLN GLN A . n A 1 520 SER 520 524 524 SER SER A . n A 1 521 VAL 521 525 525 VAL VAL A . n A 1 522 ASP 522 526 526 ASP ASP A . n A 1 523 VAL 523 527 527 VAL VAL A . n A 1 524 LEU 524 528 528 LEU LEU A . n A 1 525 ASN 525 529 529 ASN ASN A . n A 1 526 LEU 526 530 530 LEU LEU A . n A 1 527 ASN 527 531 531 ASN ASN A . n A 1 528 ALA 528 532 532 ALA ALA A . n A 1 529 TRP 529 533 533 TRP TRP A . n A 1 530 SER 530 534 534 SER SER A . n A 1 531 MET 531 535 535 MET MET A . n A 1 532 ASN 532 536 536 ASN ASN A . n A 1 533 SER 533 537 537 SER SER A . n A 1 534 ALA 534 538 538 ALA ALA A . n A 1 535 GLN 535 539 539 GLN GLN A . n A 1 536 ILE 536 540 540 ILE ILE A . n A 1 537 SER 537 541 541 SER SER A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 750 750 NAG NAG A . C 2 NAG 2 751 751 NAG NAG A . D 3 MAN 3 752 752 MAN MAN A . E 3 MAN 4 753 753 MAN MAN A . F 3 MAN 5 754 754 MAN MAN A . G 3 MAN 6 755 755 MAN MAN A . H 2 NAG 1 790 790 NAG NAG A . I 2 NAG 2 791 791 NAG NAG A . J 2 NAG 1 770 770 NAG NAG A . K 4 SUC 1 800 800 SUC SUC A . L 5 ZN 1 1101 1101 ZN ZN A . M 5 ZN 1 1102 1102 ZN ZN A . N 5 ZN 1 1103 1103 ZN ZN A . O 5 ZN 1 1104 1104 ZN ZN A . P 6 HOH 1 1001 1001 HOH HOH A . P 6 HOH 2 1002 1002 HOH HOH A . P 6 HOH 3 1003 1003 HOH HOH A . P 6 HOH 4 1004 1004 HOH HOH A . P 6 HOH 5 1005 1005 HOH HOH A . P 6 HOH 6 1006 1006 HOH HOH A . P 6 HOH 7 1007 1007 HOH HOH A . P 6 HOH 8 1008 1008 HOH HOH A . P 6 HOH 9 1009 1009 HOH HOH A . P 6 HOH 10 1010 1010 HOH HOH A . P 6 HOH 11 1011 1011 HOH HOH A . P 6 HOH 12 1012 1012 HOH HOH A . P 6 HOH 13 1013 1013 HOH HOH A . P 6 HOH 14 1014 1014 HOH HOH A . P 6 HOH 15 1015 1015 HOH HOH A . P 6 HOH 16 1016 1016 HOH HOH A . P 6 HOH 17 1017 1017 HOH HOH A . P 6 HOH 18 1018 1018 HOH HOH A . P 6 HOH 19 1019 1019 HOH HOH A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 112 A ASN 116 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 139 A ASN 143 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 295 A ASN 299 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 190 ? A HIS 194 ? 1_555 ZN ? M ZN . ? A ZN 1102 ? 1_555 OD1 ? A ASP 192 ? A ASP 196 ? 1_555 111.9 ? 2 NE2 ? A HIS 190 ? A HIS 194 ? 1_555 ZN ? M ZN . ? A ZN 1102 ? 1_555 OD2 ? A ASP 192 ? A ASP 196 ? 1_555 105.8 ? 3 OD1 ? A ASP 192 ? A ASP 196 ? 1_555 ZN ? M ZN . ? A ZN 1102 ? 1_555 OD2 ? A ASP 192 ? A ASP 196 ? 1_555 56.0 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2008-04-22 2 'Structure model' 1 1 2011-07-13 3 'Structure model' 1 2 2017-10-25 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' 3 3 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 3 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _phasing.method MR # loop_ _software.name _software.version _software.date _software.type _software.contact_author _software.contact_author_email _software.classification _software.location _software.language _software.citation_id _software.pdbx_ordinal DENZO . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data reduction' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 1 SCALEPACK . ? package 'Zbyszek Otwinowski' zbyszek@mix.swmed.edu 'data scaling' http://www.lnls.br/infra/linhasluz/denzo-hkl.htm ? ? 2 MOLREP . ? other 'A. Vagin' alexei@ysbl.york.ac.uk phasing http://www.ccp4.ac.uk/dist/html/molrep.html Fortran_77 ? 3 REFMAC 5.2.0019 ? program 'Murshudov, G.N.' ccp4@dl.ac.uk refinement http://www.ccp4.ac.uk/main.html Fortran_77 ? 4 PDB_EXTRACT 3.000 'July 2, 2007' package PDB sw-help@rcsb.rutgers.edu 'data extraction' http://pdb.rutgers.edu/software/ C++ ? 5 MAR345dtb . ? ? ? ? 'data collection' ? ? ? 6 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 CA _pdbx_validate_rmsd_angle.auth_asym_id_1 A _pdbx_validate_rmsd_angle.auth_comp_id_1 LEU _pdbx_validate_rmsd_angle.auth_seq_id_1 530 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CB _pdbx_validate_rmsd_angle.auth_asym_id_2 A _pdbx_validate_rmsd_angle.auth_comp_id_2 LEU _pdbx_validate_rmsd_angle.auth_seq_id_2 530 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 CG _pdbx_validate_rmsd_angle.auth_asym_id_3 A _pdbx_validate_rmsd_angle.auth_comp_id_3 LEU _pdbx_validate_rmsd_angle.auth_seq_id_3 530 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 131.65 _pdbx_validate_rmsd_angle.angle_target_value 115.30 _pdbx_validate_rmsd_angle.angle_deviation 16.35 _pdbx_validate_rmsd_angle.angle_standard_deviation 2.30 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PHE A 12 ? ? -147.35 14.81 2 1 ASN A 19 ? ? 78.21 -175.02 3 1 ASN A 22 ? ? -126.26 -131.15 4 1 LEU A 60 ? ? 72.80 -2.54 5 1 SER A 73 ? ? -151.82 -9.76 6 1 ASP A 77 ? ? -146.90 18.85 7 1 LEU A 122 ? ? 33.96 55.98 8 1 SER A 146 ? ? -151.46 60.18 9 1 PHE A 147 ? ? -151.30 77.92 10 1 ASP A 149 ? ? 67.18 71.35 11 1 HIS A 170 ? ? -125.90 -88.16 12 1 LEU A 184 ? ? -133.07 -30.56 13 1 CYS A 204 ? ? 38.21 59.25 14 1 ASN A 352 ? ? 32.46 54.96 15 1 LEU A 418 ? ? 39.13 55.51 16 1 ARG A 437 ? ? -76.54 35.94 17 1 ASN A 441 ? ? -90.58 41.14 18 1 HIS A 485 ? ? 64.15 -66.76 19 1 ASN A 519 ? ? -164.67 107.88 # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C1 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id A _pdbx_validate_chiral.auth_comp_id MAN _pdbx_validate_chiral.auth_seq_id 752 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A LYS 265 ? A LYS 261 2 1 Y 1 A MET 266 ? A MET 262 3 1 Y 1 A ASP 267 ? A ASP 263 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 ALPHA-D-MANNOSE MAN 4 SUCROSE SUC 5 'ZINC ION' ZN 6 water HOH #