data_2QMJ # _entry.id 2QMJ # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.279 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2QMJ RCSB RCSB043785 WWPDB D_1000043785 # _pdbx_database_related.db_name PDB _pdbx_database_related.db_id 2QLY _pdbx_database_related.details . _pdbx_database_related.content_type unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2QMJ _pdbx_database_status.recvd_initial_deposition_date 2007-07-16 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.status_code_sf REL _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Sim, L.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title ;Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity ; _citation.journal_abbrev J.Mol.Biol. _citation.journal_volume 375 _citation.page_first 782 _citation.page_last 792 _citation.year 2008 _citation.journal_id_ASTM JMOBAK _citation.country UK _citation.journal_id_ISSN 0022-2836 _citation.journal_id_CSD 0070 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 18036614 _citation.pdbx_database_id_DOI 10.1016/j.jmb.2007.10.069 # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Sim, L.' 1 primary 'Quezada-Calvillo, R.' 2 primary 'Sterchi, E.E.' 3 primary 'Nichols, B.L.' 4 primary 'Rose, D.R.' 5 # _cell.entry_id 2QMJ _cell.length_a 86.970 _cell.length_b 109.367 _cell.length_c 109.271 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2QMJ _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'Maltase-glucoamylase, intestinal' 98585.992 1 3.2.1.- ? 'SEQUENCE DATABASE RESIDUES 87-954' ? 2 non-polymer man ALPHA-ACARBOSE 645.605 1 ? ? ? ? 3 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 4 ? ? ? ? 4 non-polymer syn 'SULFATE ION' 96.063 1 ? ? ? ? 5 non-polymer syn GLYCEROL 92.094 9 ? ? ? ? 6 water nat water 18.015 626 ? ? ? ? # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAH ; _entity_poly.pdbx_seq_one_letter_code_can ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEWAH ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 ALA n 1 3 GLU n 1 4 CYS n 1 5 PRO n 1 6 VAL n 1 7 VAL n 1 8 ASN n 1 9 GLU n 1 10 LEU n 1 11 GLU n 1 12 ARG n 1 13 ILE n 1 14 ASN n 1 15 CYS n 1 16 ILE n 1 17 PRO n 1 18 ASP n 1 19 GLN n 1 20 PRO n 1 21 PRO n 1 22 THR n 1 23 LYS n 1 24 ALA n 1 25 THR n 1 26 CYS n 1 27 ASP n 1 28 GLN n 1 29 ARG n 1 30 GLY n 1 31 CYS n 1 32 CYS n 1 33 TRP n 1 34 ASN n 1 35 PRO n 1 36 GLN n 1 37 GLY n 1 38 ALA n 1 39 VAL n 1 40 SER n 1 41 VAL n 1 42 PRO n 1 43 TRP n 1 44 CYS n 1 45 TYR n 1 46 TYR n 1 47 SER n 1 48 LYS n 1 49 ASN n 1 50 HIS n 1 51 SER n 1 52 TYR n 1 53 HIS n 1 54 VAL n 1 55 GLU n 1 56 GLY n 1 57 ASN n 1 58 LEU n 1 59 VAL n 1 60 ASN n 1 61 THR n 1 62 ASN n 1 63 ALA n 1 64 GLY n 1 65 PHE n 1 66 THR n 1 67 ALA n 1 68 ARG n 1 69 LEU n 1 70 LYS n 1 71 ASN n 1 72 LEU n 1 73 PRO n 1 74 SER n 1 75 SER n 1 76 PRO n 1 77 VAL n 1 78 PHE n 1 79 GLY n 1 80 SER n 1 81 ASN n 1 82 VAL n 1 83 ASP n 1 84 ASN n 1 85 VAL n 1 86 LEU n 1 87 LEU n 1 88 THR n 1 89 ALA n 1 90 GLU n 1 91 TYR n 1 92 GLN n 1 93 THR n 1 94 SER n 1 95 ASN n 1 96 ARG n 1 97 PHE n 1 98 HIS n 1 99 PHE n 1 100 LYS n 1 101 LEU n 1 102 THR n 1 103 ASP n 1 104 GLN n 1 105 THR n 1 106 ASN n 1 107 ASN n 1 108 ARG n 1 109 PHE n 1 110 GLU n 1 111 VAL n 1 112 PRO n 1 113 HIS n 1 114 GLU n 1 115 HIS n 1 116 VAL n 1 117 GLN n 1 118 SER n 1 119 PHE n 1 120 SER n 1 121 GLY n 1 122 ASN n 1 123 ALA n 1 124 ALA n 1 125 ALA n 1 126 SER n 1 127 LEU n 1 128 THR n 1 129 TYR n 1 130 GLN n 1 131 VAL n 1 132 GLU n 1 133 ILE n 1 134 SER n 1 135 ARG n 1 136 GLN n 1 137 PRO n 1 138 PHE n 1 139 SER n 1 140 ILE n 1 141 LYS n 1 142 VAL n 1 143 THR n 1 144 ARG n 1 145 ARG n 1 146 SER n 1 147 ASN n 1 148 ASN n 1 149 ARG n 1 150 VAL n 1 151 LEU n 1 152 PHE n 1 153 ASP n 1 154 SER n 1 155 SER n 1 156 ILE n 1 157 GLY n 1 158 PRO n 1 159 LEU n 1 160 LEU n 1 161 PHE n 1 162 ALA n 1 163 ASP n 1 164 GLN n 1 165 PHE n 1 166 LEU n 1 167 GLN n 1 168 LEU n 1 169 SER n 1 170 THR n 1 171 ARG n 1 172 LEU n 1 173 PRO n 1 174 SER n 1 175 THR n 1 176 ASN n 1 177 VAL n 1 178 TYR n 1 179 GLY n 1 180 LEU n 1 181 GLY n 1 182 GLU n 1 183 HIS n 1 184 VAL n 1 185 HIS n 1 186 GLN n 1 187 GLN n 1 188 TYR n 1 189 ARG n 1 190 HIS n 1 191 ASP n 1 192 MET n 1 193 ASN n 1 194 TRP n 1 195 LYS n 1 196 THR n 1 197 TRP n 1 198 PRO n 1 199 ILE n 1 200 PHE n 1 201 ASN n 1 202 ARG n 1 203 ASP n 1 204 THR n 1 205 THR n 1 206 PRO n 1 207 ASN n 1 208 GLY n 1 209 ASN n 1 210 GLY n 1 211 THR n 1 212 ASN n 1 213 LEU n 1 214 TYR n 1 215 GLY n 1 216 ALA n 1 217 GLN n 1 218 THR n 1 219 PHE n 1 220 PHE n 1 221 LEU n 1 222 CYS n 1 223 LEU n 1 224 GLU n 1 225 ASP n 1 226 ALA n 1 227 SER n 1 228 GLY n 1 229 LEU n 1 230 SER n 1 231 PHE n 1 232 GLY n 1 233 VAL n 1 234 PHE n 1 235 LEU n 1 236 MET n 1 237 ASN n 1 238 SER n 1 239 ASN n 1 240 ALA n 1 241 MET n 1 242 GLU n 1 243 VAL n 1 244 VAL n 1 245 LEU n 1 246 GLN n 1 247 PRO n 1 248 ALA n 1 249 PRO n 1 250 ALA n 1 251 ILE n 1 252 THR n 1 253 TYR n 1 254 ARG n 1 255 THR n 1 256 ILE n 1 257 GLY n 1 258 GLY n 1 259 ILE n 1 260 LEU n 1 261 ASP n 1 262 PHE n 1 263 TYR n 1 264 VAL n 1 265 PHE n 1 266 LEU n 1 267 GLY n 1 268 ASN n 1 269 THR n 1 270 PRO n 1 271 GLU n 1 272 GLN n 1 273 VAL n 1 274 VAL n 1 275 GLN n 1 276 GLU n 1 277 TYR n 1 278 LEU n 1 279 GLU n 1 280 LEU n 1 281 ILE n 1 282 GLY n 1 283 ARG n 1 284 PRO n 1 285 ALA n 1 286 LEU n 1 287 PRO n 1 288 SER n 1 289 TYR n 1 290 TRP n 1 291 ALA n 1 292 LEU n 1 293 GLY n 1 294 PHE n 1 295 HIS n 1 296 LEU n 1 297 SER n 1 298 ARG n 1 299 TYR n 1 300 GLU n 1 301 TYR n 1 302 GLY n 1 303 THR n 1 304 LEU n 1 305 ASP n 1 306 ASN n 1 307 MET n 1 308 ARG n 1 309 GLU n 1 310 VAL n 1 311 VAL n 1 312 GLU n 1 313 ARG n 1 314 ASN n 1 315 ARG n 1 316 ALA n 1 317 ALA n 1 318 GLN n 1 319 LEU n 1 320 PRO n 1 321 TYR n 1 322 ASP n 1 323 VAL n 1 324 GLN n 1 325 HIS n 1 326 ALA n 1 327 ASP n 1 328 ILE n 1 329 ASP n 1 330 TYR n 1 331 MET n 1 332 ASP n 1 333 GLU n 1 334 ARG n 1 335 ARG n 1 336 ASP n 1 337 PHE n 1 338 THR n 1 339 TYR n 1 340 ASP n 1 341 SER n 1 342 VAL n 1 343 ASP n 1 344 PHE n 1 345 LYS n 1 346 GLY n 1 347 PHE n 1 348 PRO n 1 349 GLU n 1 350 PHE n 1 351 VAL n 1 352 ASN n 1 353 GLU n 1 354 LEU n 1 355 HIS n 1 356 ASN n 1 357 ASN n 1 358 GLY n 1 359 GLN n 1 360 LYS n 1 361 LEU n 1 362 VAL n 1 363 ILE n 1 364 ILE n 1 365 VAL n 1 366 ASP n 1 367 PRO n 1 368 ALA n 1 369 ILE n 1 370 SER n 1 371 ASN n 1 372 ASN n 1 373 SER n 1 374 SER n 1 375 SER n 1 376 SER n 1 377 LYS n 1 378 PRO n 1 379 TYR n 1 380 GLY n 1 381 PRO n 1 382 TYR n 1 383 ASP n 1 384 ARG n 1 385 GLY n 1 386 SER n 1 387 ASP n 1 388 MET n 1 389 LYS n 1 390 ILE n 1 391 TRP n 1 392 VAL n 1 393 ASN n 1 394 SER n 1 395 SER n 1 396 ASP n 1 397 GLY n 1 398 VAL n 1 399 THR n 1 400 PRO n 1 401 LEU n 1 402 ILE n 1 403 GLY n 1 404 GLU n 1 405 VAL n 1 406 TRP n 1 407 PRO n 1 408 GLY n 1 409 GLN n 1 410 THR n 1 411 VAL n 1 412 PHE n 1 413 PRO n 1 414 ASP n 1 415 TYR n 1 416 THR n 1 417 ASN n 1 418 PRO n 1 419 ASN n 1 420 CYS n 1 421 ALA n 1 422 VAL n 1 423 TRP n 1 424 TRP n 1 425 THR n 1 426 LYS n 1 427 GLU n 1 428 PHE n 1 429 GLU n 1 430 LEU n 1 431 PHE n 1 432 HIS n 1 433 ASN n 1 434 GLN n 1 435 VAL n 1 436 GLU n 1 437 PHE n 1 438 ASP n 1 439 GLY n 1 440 ILE n 1 441 TRP n 1 442 ILE n 1 443 ASP n 1 444 MET n 1 445 ASN n 1 446 GLU n 1 447 VAL n 1 448 SER n 1 449 ASN n 1 450 PHE n 1 451 VAL n 1 452 ASP n 1 453 GLY n 1 454 SER n 1 455 VAL n 1 456 SER n 1 457 GLY n 1 458 CYS n 1 459 SER n 1 460 THR n 1 461 ASN n 1 462 ASN n 1 463 LEU n 1 464 ASN n 1 465 ASN n 1 466 PRO n 1 467 PRO n 1 468 PHE n 1 469 THR n 1 470 PRO n 1 471 ARG n 1 472 ILE n 1 473 LEU n 1 474 ASP n 1 475 GLY n 1 476 TYR n 1 477 LEU n 1 478 PHE n 1 479 CYS n 1 480 LYS n 1 481 THR n 1 482 LEU n 1 483 CYS n 1 484 MET n 1 485 ASP n 1 486 ALA n 1 487 VAL n 1 488 GLN n 1 489 HIS n 1 490 TRP n 1 491 GLY n 1 492 LYS n 1 493 GLN n 1 494 TYR n 1 495 ASP n 1 496 ILE n 1 497 HIS n 1 498 ASN n 1 499 LEU n 1 500 TYR n 1 501 GLY n 1 502 TYR n 1 503 SER n 1 504 MET n 1 505 ALA n 1 506 VAL n 1 507 ALA n 1 508 THR n 1 509 ALA n 1 510 GLU n 1 511 ALA n 1 512 ALA n 1 513 LYS n 1 514 THR n 1 515 VAL n 1 516 PHE n 1 517 PRO n 1 518 ASN n 1 519 LYS n 1 520 ARG n 1 521 SER n 1 522 PHE n 1 523 ILE n 1 524 LEU n 1 525 THR n 1 526 ARG n 1 527 SER n 1 528 THR n 1 529 PHE n 1 530 ALA n 1 531 GLY n 1 532 SER n 1 533 GLY n 1 534 LYS n 1 535 PHE n 1 536 ALA n 1 537 ALA n 1 538 HIS n 1 539 TRP n 1 540 LEU n 1 541 GLY n 1 542 ASP n 1 543 ASN n 1 544 THR n 1 545 ALA n 1 546 THR n 1 547 TRP n 1 548 ASP n 1 549 ASP n 1 550 LEU n 1 551 ARG n 1 552 TRP n 1 553 SER n 1 554 ILE n 1 555 PRO n 1 556 GLY n 1 557 VAL n 1 558 LEU n 1 559 GLU n 1 560 PHE n 1 561 ASN n 1 562 LEU n 1 563 PHE n 1 564 GLY n 1 565 ILE n 1 566 PRO n 1 567 MET n 1 568 VAL n 1 569 GLY n 1 570 PRO n 1 571 ASP n 1 572 ILE n 1 573 CYS n 1 574 GLY n 1 575 PHE n 1 576 ALA n 1 577 LEU n 1 578 ASP n 1 579 THR n 1 580 PRO n 1 581 GLU n 1 582 GLU n 1 583 LEU n 1 584 CYS n 1 585 ARG n 1 586 ARG n 1 587 TRP n 1 588 MET n 1 589 GLN n 1 590 LEU n 1 591 GLY n 1 592 ALA n 1 593 PHE n 1 594 TYR n 1 595 PRO n 1 596 PHE n 1 597 SER n 1 598 ARG n 1 599 ASN n 1 600 HIS n 1 601 ASN n 1 602 GLY n 1 603 GLN n 1 604 GLY n 1 605 TYR n 1 606 LYS n 1 607 ASP n 1 608 GLN n 1 609 ASP n 1 610 PRO n 1 611 ALA n 1 612 SER n 1 613 PHE n 1 614 GLY n 1 615 ALA n 1 616 ASP n 1 617 SER n 1 618 LEU n 1 619 LEU n 1 620 LEU n 1 621 ASN n 1 622 SER n 1 623 SER n 1 624 ARG n 1 625 HIS n 1 626 TYR n 1 627 LEU n 1 628 ASN n 1 629 ILE n 1 630 ARG n 1 631 TYR n 1 632 THR n 1 633 LEU n 1 634 LEU n 1 635 PRO n 1 636 TYR n 1 637 LEU n 1 638 TYR n 1 639 THR n 1 640 LEU n 1 641 PHE n 1 642 PHE n 1 643 ARG n 1 644 ALA n 1 645 HIS n 1 646 SER n 1 647 ARG n 1 648 GLY n 1 649 ASP n 1 650 THR n 1 651 VAL n 1 652 ALA n 1 653 ARG n 1 654 PRO n 1 655 LEU n 1 656 LEU n 1 657 HIS n 1 658 GLU n 1 659 PHE n 1 660 TYR n 1 661 GLU n 1 662 ASP n 1 663 ASN n 1 664 SER n 1 665 THR n 1 666 TRP n 1 667 ASP n 1 668 VAL n 1 669 HIS n 1 670 GLN n 1 671 GLN n 1 672 PHE n 1 673 LEU n 1 674 TRP n 1 675 GLY n 1 676 PRO n 1 677 GLY n 1 678 LEU n 1 679 LEU n 1 680 ILE n 1 681 THR n 1 682 PRO n 1 683 VAL n 1 684 LEU n 1 685 ASP n 1 686 GLU n 1 687 GLY n 1 688 ALA n 1 689 GLU n 1 690 LYS n 1 691 VAL n 1 692 MET n 1 693 ALA n 1 694 TYR n 1 695 VAL n 1 696 PRO n 1 697 ASP n 1 698 ALA n 1 699 VAL n 1 700 TRP n 1 701 TYR n 1 702 ASP n 1 703 TYR n 1 704 GLU n 1 705 THR n 1 706 GLY n 1 707 SER n 1 708 GLN n 1 709 VAL n 1 710 ARG n 1 711 TRP n 1 712 ARG n 1 713 LYS n 1 714 GLN n 1 715 LYS n 1 716 VAL n 1 717 GLU n 1 718 MET n 1 719 GLU n 1 720 LEU n 1 721 PRO n 1 722 GLY n 1 723 ASP n 1 724 LYS n 1 725 ILE n 1 726 GLY n 1 727 LEU n 1 728 HIS n 1 729 LEU n 1 730 ARG n 1 731 GLY n 1 732 GLY n 1 733 TYR n 1 734 ILE n 1 735 PHE n 1 736 PRO n 1 737 THR n 1 738 GLN n 1 739 GLN n 1 740 PRO n 1 741 ASN n 1 742 THR n 1 743 THR n 1 744 THR n 1 745 LEU n 1 746 ALA n 1 747 SER n 1 748 ARG n 1 749 LYS n 1 750 ASN n 1 751 PRO n 1 752 LEU n 1 753 GLY n 1 754 LEU n 1 755 ILE n 1 756 ILE n 1 757 ALA n 1 758 LEU n 1 759 ASP n 1 760 GLU n 1 761 ASN n 1 762 LYS n 1 763 GLU n 1 764 ALA n 1 765 LYS n 1 766 GLY n 1 767 GLU n 1 768 LEU n 1 769 PHE n 1 770 TRP n 1 771 ASP n 1 772 ASP n 1 773 GLY n 1 774 GLU n 1 775 THR n 1 776 LYS n 1 777 ASP n 1 778 THR n 1 779 VAL n 1 780 ALA n 1 781 ASN n 1 782 LYS n 1 783 VAL n 1 784 TYR n 1 785 LEU n 1 786 LEU n 1 787 CYS n 1 788 GLU n 1 789 PHE n 1 790 SER n 1 791 VAL n 1 792 THR n 1 793 GLN n 1 794 ASN n 1 795 ARG n 1 796 LEU n 1 797 GLU n 1 798 VAL n 1 799 ASN n 1 800 ILE n 1 801 SER n 1 802 GLN n 1 803 SER n 1 804 THR n 1 805 TYR n 1 806 LYS n 1 807 ASP n 1 808 PRO n 1 809 ASN n 1 810 ASN n 1 811 LEU n 1 812 ALA n 1 813 PHE n 1 814 ASN n 1 815 GLU n 1 816 ILE n 1 817 LYS n 1 818 ILE n 1 819 LEU n 1 820 GLY n 1 821 THR n 1 822 GLU n 1 823 GLU n 1 824 PRO n 1 825 SER n 1 826 ASN n 1 827 VAL n 1 828 THR n 1 829 VAL n 1 830 LYS n 1 831 HIS n 1 832 ASN n 1 833 GLY n 1 834 VAL n 1 835 PRO n 1 836 SER n 1 837 GLN n 1 838 THR n 1 839 SER n 1 840 PRO n 1 841 THR n 1 842 VAL n 1 843 THR n 1 844 TYR n 1 845 ASP n 1 846 SER n 1 847 ASN n 1 848 LEU n 1 849 LYS n 1 850 VAL n 1 851 ALA n 1 852 ILE n 1 853 ILE n 1 854 THR n 1 855 ASP n 1 856 ILE n 1 857 ASP n 1 858 LEU n 1 859 LEU n 1 860 LEU n 1 861 GLY n 1 862 GLU n 1 863 ALA n 1 864 TYR n 1 865 THR n 1 866 VAL n 1 867 GLU n 1 868 TRP n 1 869 ALA n 1 870 HIS n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name human _entity_src_gen.gene_src_genus Homo _entity_src_gen.pdbx_gene_src_gene 'MGAM, MGA, MGAML' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Homo sapiens' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 9606 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fruit fly' _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus Drosophila _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type Plasmid _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMT-BiP-V5-His _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MGA_HUMAN _struct_ref.pdbx_db_accession O43451 _struct_ref.entity_id 1 _struct_ref.pdbx_seq_one_letter_code ;SAECPVVNELERINCIPDQPPTKATCDQRGCCWNPQGAVSVPWCYYSKNHSYHVEGNLVNTNAGFTARLKNLPSSPVFGS NVDNVLLTAEYQTSNRFHFKLTDQTNNRFEVPHEHVQSFSGNAAASLTYQVEISRQPFSIKVTRRSNNRVLFDSSIGPLL FADQFLQLSTRLPSTNVYGLGEHVHQQYRHDMNWKTWPIFNRDTTPNGNGTNLYGAQTFFLCLEDASGLSFGVFLMNSNA MEVVLQPAPAITYRTIGGILDFYVFLGNTPEQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLP YDVQHADIDYMDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKIWVNSSDGVTP LIGEVWPGQTVFPDYTNPNCAVWWTKEFELFHNQVEFDGIWIDMNEVSNFVDGSVSGCSTNNLNNPPFTPRILDGYLFCK TLCMDAVQHWGKQYDIHNLYGYSMAVATAEAAKTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEF NLFGIPMVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHYLNIRYTLLPYLYTL FFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDEGAEKVMAYVPDAVWYDYETGSQVRWRKQKVEMEL PGDKIGLHLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAKGELFWDDGETKDTVANKVYLLCEFSVTQNRLEVNI SQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGEAYTVEW ; _struct_ref.pdbx_align_begin 87 _struct_ref.pdbx_db_isoform ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 2QMJ _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 1 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 868 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession O43451 _struct_ref_seq.db_align_beg 87 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 954 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 1 _struct_ref_seq.pdbx_auth_seq_align_end 868 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 2QMJ ALA A 869 ? UNP O43451 ? ? 'EXPRESSION TAG' 869 1 1 2QMJ HIS A 870 ? UNP O43451 ? ? 'EXPRESSION TAG' 870 2 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ACR saccharide . ALPHA-ACARBOSE '1,4-DEOXY-4-((5-HYDROXYMETHYL-2,3,4-TRIHYDROXYCYCLOHEX-5,6-ENYL)AMINO)FRUCTOSE' 'C25 H43 N O18' 645.605 ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 GOL non-polymer . GLYCEROL 'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3' 92.094 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 SO4 non-polymer . 'SULFATE ION' ? 'O4 S -2' 96.063 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 2QMJ _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number 1 # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.64 _exptl_crystal.density_percent_sol 53.33 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.temp 293 _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pH 6.5 _exptl_crystal_grow.pdbx_details '20% PEG 3350, 0.2M sodium sulfate, 4% 1,1,1,3,3,3-hexafluoro-2-propanol, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K' _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2007-05-19 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator ? _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.9175 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE F1' _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline F1 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 0.9175 # _reflns.entry_id 2QMJ _reflns.observed_criterion_sigma_F ? _reflns.observed_criterion_sigma_I -3.0 _reflns.d_resolution_high 1.9 _reflns.d_resolution_low 30 _reflns.number_all ? _reflns.number_obs 82234 _reflns.percent_possible_obs 98.7 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value 0.109 _reflns.pdbx_netI_over_sigmaI 15.3 _reflns.B_iso_Wilson_estimate ? _reflns.pdbx_redundancy 7.6 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 1.90 _reflns_shell.d_res_low 1.97 _reflns_shell.percent_possible_all 96.2 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value 0.401 _reflns_shell.meanI_over_sigI_obs 3.4 _reflns_shell.pdbx_redundancy 6.4 _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all 7898 _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2QMJ _refine.ls_number_reflns_obs 77676 _refine.ls_number_reflns_all 77676 _refine.pdbx_ls_sigma_I ? _refine.pdbx_ls_sigma_F ? _refine.pdbx_data_cutoff_high_absF ? _refine.pdbx_data_cutoff_low_absF ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 19.78 _refine.ls_d_res_high 1.9 _refine.ls_percent_reflns_obs 98.16 _refine.ls_R_factor_obs 0.17923 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.17729 _refine.ls_R_factor_R_free 0.21516 _refine.ls_R_factor_R_free_error ? _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 5.0 _refine.ls_number_reflns_R_free 4082 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc 0.954 _refine.correlation_coeff_Fo_to_Fc_free 0.939 _refine.B_iso_mean 24.108 _refine.aniso_B[1][1] 0.00 _refine.aniso_B[2][2] 0.00 _refine.aniso_B[3][3] 0.00 _refine.aniso_B[1][2] 0.00 _refine.aniso_B[1][3] 0.00 _refine.aniso_B[2][3] 0.00 _refine.solvent_model_details MASK _refine.solvent_model_param_ksol ? _refine.solvent_model_param_bsol ? _refine.pdbx_solvent_vdw_probe_radii 1.40 _refine.pdbx_solvent_ion_probe_radii 0.80 _refine.pdbx_solvent_shrinkage_radii 0.80 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details 'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' _refine.pdbx_starting_model 'PDB entry 2QLY' _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model ? _refine.pdbx_stereochemistry_target_values 'MAXIMUM LIKELIHOOD' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R 0.140 _refine.pdbx_overall_ESU_R_Free 0.132 _refine.overall_SU_ML 0.091 _refine.overall_SU_B 3.081 _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 6912 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 159 _refine_hist.number_atoms_solvent 626 _refine_hist.number_atoms_total 7697 _refine_hist.d_res_high 1.9 _refine_hist.d_res_low 19.78 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function r_bond_refined_d 0.016 0.022 ? 7319 'X-RAY DIFFRACTION' ? r_angle_refined_deg 1.672 1.959 ? 9986 'X-RAY DIFFRACTION' ? r_dihedral_angle_1_deg 6.847 5.000 ? 871 'X-RAY DIFFRACTION' ? r_dihedral_angle_2_deg 36.176 24.317 ? 366 'X-RAY DIFFRACTION' ? r_dihedral_angle_3_deg 12.914 15.000 ? 1103 'X-RAY DIFFRACTION' ? r_dihedral_angle_4_deg 18.486 15.000 ? 39 'X-RAY DIFFRACTION' ? r_chiral_restr 0.116 0.200 ? 1080 'X-RAY DIFFRACTION' ? r_gen_planes_refined 0.007 0.020 ? 5660 'X-RAY DIFFRACTION' ? r_nbd_refined 0.209 0.200 ? 3620 'X-RAY DIFFRACTION' ? r_nbtor_refined 0.318 0.200 ? 5025 'X-RAY DIFFRACTION' ? r_xyhbond_nbd_refined 0.162 0.200 ? 662 'X-RAY DIFFRACTION' ? r_symmetry_vdw_refined 0.240 0.200 ? 68 'X-RAY DIFFRACTION' ? r_symmetry_hbond_refined 0.171 0.200 ? 20 'X-RAY DIFFRACTION' ? r_mcbond_it 1.110 1.500 ? 4424 'X-RAY DIFFRACTION' ? r_mcangle_it 1.750 2.000 ? 7006 'X-RAY DIFFRACTION' ? r_scbond_it 2.713 3.000 ? 3328 'X-RAY DIFFRACTION' ? r_scangle_it 4.098 4.500 ? 2971 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 20 _refine_ls_shell.d_res_high 1.9 _refine_ls_shell.d_res_low 1.943 _refine_ls_shell.number_reflns_R_work 5349 _refine_ls_shell.R_factor_R_work 0.259 _refine_ls_shell.percent_reflns_obs 93.15 _refine_ls_shell.R_factor_R_free 0.343 _refine_ls_shell.R_factor_R_free_error ? _refine_ls_shell.percent_reflns_R_free ? _refine_ls_shell.number_reflns_R_free 269 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # _struct.entry_id 2QMJ _struct.title 'Crystral Structure of the N-terminal Subunit of Human Maltase-Glucoamylase in Complex with Acarbose' _struct.pdbx_descriptor 'Maltase-glucoamylase, intestinal' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2QMJ _struct_keywords.pdbx_keywords HYDROLASE _struct_keywords.text ;Hydrolase, Glycosyl Hydrolase Family 31, Glycoprotein, Glycosidase, Membrane, Multifunctional enzyme, Signal-anchor, Sulfation, Transmembrane ; # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 3 ? E N N 4 ? F N N 5 ? G N N 5 ? H N N 5 ? I N N 5 ? J N N 5 ? K N N 5 ? L N N 5 ? M N N 5 ? N N N 5 ? O N N 3 ? P N N 3 ? Q N N 6 ? # loop_ _struct_biol.id _struct_biol.details 1 'The biological assembly is a monomer' 0 ? # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 ASN A 8 ? ARG A 12 ? ASN A 8 ARG A 12 5 ? 5 HELX_P HELX_P2 2 THR A 22 ? GLY A 30 ? THR A 22 GLY A 30 1 ? 9 HELX_P HELX_P3 3 SER A 155 ? GLY A 157 ? SER A 155 GLY A 157 5 ? 3 HELX_P HELX_P4 4 THR A 269 ? GLY A 282 ? THR A 269 GLY A 282 1 ? 14 HELX_P HELX_P5 5 SER A 288 ? LEU A 292 ? SER A 288 LEU A 292 5 ? 5 HELX_P HELX_P6 6 THR A 303 ? ALA A 317 ? THR A 303 ALA A 317 1 ? 15 HELX_P HELX_P7 7 ASP A 327 ? MET A 331 ? ASP A 327 MET A 331 5 ? 5 HELX_P HELX_P8 8 GLY A 346 ? ASN A 357 ? GLY A 346 ASN A 357 1 ? 12 HELX_P HELX_P9 9 TYR A 379 ? LYS A 389 ? TYR A 379 LYS A 389 1 ? 11 HELX_P HELX_P10 10 ASN A 417 ? ASN A 433 ? ASN A 417 ASN A 433 1 ? 17 HELX_P HELX_P11 11 ILE A 472 ? TYR A 476 ? ILE A 472 TYR A 476 5 ? 5 HELX_P HELX_P12 12 GLN A 493 ? HIS A 497 ? GLN A 493 HIS A 497 1 ? 5 HELX_P HELX_P13 13 LEU A 499 ? PHE A 516 ? LEU A 499 PHE A 516 1 ? 18 HELX_P HELX_P14 14 GLY A 531 ? PHE A 535 ? GLY A 531 PHE A 535 5 ? 5 HELX_P HELX_P15 15 THR A 546 ? PHE A 563 ? THR A 546 PHE A 563 1 ? 18 HELX_P HELX_P16 16 PRO A 580 ? ALA A 592 ? PRO A 580 ALA A 592 1 ? 13 HELX_P HELX_P17 17 ASP A 609 ? GLY A 614 ? ASP A 609 GLY A 614 5 ? 6 HELX_P HELX_P18 18 SER A 617 ? LEU A 633 ? SER A 617 LEU A 633 1 ? 17 HELX_P HELX_P19 19 LEU A 633 ? ARG A 647 ? LEU A 633 ARG A 647 1 ? 15 HELX_P HELX_P20 20 PRO A 654 ? PHE A 659 ? PRO A 654 PHE A 659 1 ? 6 HELX_P HELX_P21 21 ASP A 662 ? TRP A 666 ? ASP A 662 TRP A 666 5 ? 5 HELX_P HELX_P22 22 THR A 743 ? ARG A 748 ? THR A 743 ARG A 748 1 ? 6 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 15 SG ? ? ? 1_555 A CYS 31 SG ? ? A CYS 15 A CYS 31 1_555 ? ? ? ? ? ? ? 2.063 ? disulf2 disulf ? ? A CYS 26 SG ? ? ? 1_555 A CYS 44 SG ? ? A CYS 26 A CYS 44 1_555 ? ? ? ? ? ? ? 2.916 ? disulf3 disulf ? ? A CYS 573 SG ? ? ? 1_555 A CYS 584 SG ? ? A CYS 573 A CYS 584 1_555 ? ? ? ? ? ? ? 2.086 ? covale1 covale ? ? A ASN 209 ND2 ? ? ? 1_555 D NAG . C1 ? ? A ASN 209 A NAG 2005 1_555 ? ? ? ? ? ? ? 1.455 ? covale2 covale ? ? A ASN 393 ND2 ? ? ? 1_555 O NAG . C1 ? ? A ASN 393 X NAG 2003 1_555 ? ? ? ? ? ? ? 1.444 ? covale3 covale ? ? A ASN 741 ND2 A ? ? 1_555 C NAG . C1 A ? A ASN 741 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.455 ? covale4 covale ? ? A ASN 741 ND2 B ? ? 1_555 C NAG . C1 B ? A ASN 741 A NAG 2001 1_555 ? ? ? ? ? ? ? 1.449 ? covale5 covale ? ? O NAG . O4 ? ? ? 1_555 P NAG . C1 ? ? X NAG 2003 X NAG 2004 1_555 ? ? ? ? ? ? ? 1.442 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 GLN 136 A . ? GLN 136 A PRO 137 A ? PRO 137 A 1 3.32 2 GLY 181 A . ? GLY 181 A GLU 182 A ? GLU 182 A 1 -3.15 3 ALA 248 A . ? ALA 248 A PRO 249 A ? PRO 249 A 1 -2.67 4 GLU 446 A . ? GLU 446 A VAL 447 A ? VAL 447 A 1 4.87 5 PRO 835 A . ? PRO 835 A SER 836 A ? SER 836 A 1 15.30 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 8 ? C ? 3 ? D ? 5 ? E ? 9 ? F ? 3 ? G ? 2 ? H ? 5 ? I ? 2 ? J ? 10 ? K ? 9 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? anti-parallel B 2 3 ? anti-parallel B 3 4 ? anti-parallel B 4 5 ? anti-parallel B 5 6 ? anti-parallel B 6 7 ? anti-parallel B 7 8 ? anti-parallel C 1 2 ? anti-parallel C 2 3 ? anti-parallel D 1 2 ? anti-parallel D 2 3 ? anti-parallel D 3 4 ? anti-parallel D 4 5 ? anti-parallel E 1 2 ? parallel E 2 3 ? parallel E 3 4 ? parallel E 4 5 ? parallel E 5 6 ? parallel E 6 7 ? parallel E 7 8 ? parallel E 8 9 ? parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? parallel J 6 7 ? anti-parallel J 7 8 ? parallel J 8 9 ? anti-parallel J 9 10 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel K 5 6 ? parallel K 6 7 ? anti-parallel K 7 8 ? parallel K 8 9 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 CYS A 32 ? TRP A 33 ? CYS A 32 TRP A 33 A 2 CYS A 44 ? TYR A 45 ? CYS A 44 TYR A 45 B 1 TYR A 52 ? ASN A 60 ? TYR A 52 ASN A 60 B 2 GLY A 64 ? ASN A 71 ? GLY A 64 ASN A 71 B 3 ASN A 84 ? THR A 93 ? ASN A 84 THR A 93 B 4 ARG A 96 ? ASP A 103 ? ARG A 96 ASP A 103 B 5 LEU A 260 ? GLY A 267 ? LEU A 260 GLY A 267 B 6 SER A 230 ? LEU A 235 ? SER A 230 LEU A 235 B 7 GLN A 217 ? LEU A 223 ? GLN A 217 LEU A 223 B 8 VAL A 177 ? GLY A 181 ? VAL A 177 GLY A 181 C 1 TYR A 129 ? SER A 134 ? TYR A 129 SER A 134 C 2 SER A 139 ? ARG A 144 ? SER A 139 ARG A 144 C 3 VAL A 150 ? ASP A 153 ? VAL A 150 ASP A 153 D 1 LEU A 160 ? ALA A 162 ? LEU A 160 ALA A 162 D 2 PHE A 165 ? ARG A 171 ? PHE A 165 ARG A 171 D 3 ALA A 250 ? THR A 255 ? ALA A 250 THR A 255 D 4 MET A 241 ? GLN A 246 ? MET A 241 GLN A 246 D 5 LYS A 195 ? ILE A 199 ? LYS A 195 ILE A 199 E 1 VAL A 568 ? GLY A 569 ? VAL A 568 GLY A 569 E 2 ALA A 537 ? TRP A 539 ? ALA A 537 TRP A 539 E 3 ILE A 523 ? THR A 525 ? ILE A 523 THR A 525 E 4 GLY A 439 ? ILE A 442 ? GLY A 439 ILE A 442 E 5 LYS A 360 ? VAL A 365 ? LYS A 360 VAL A 365 E 6 VAL A 323 ? ALA A 326 ? VAL A 323 ALA A 326 E 7 PHE A 294 ? LEU A 296 ? PHE A 294 LEU A 296 E 8 SER A 597 ? ASN A 599 ? SER A 597 ASN A 599 E 9 ASP A 571 ? ILE A 572 ? ASP A 571 ILE A 572 F 1 ILE A 369 ? SER A 370 ? ILE A 369 SER A 370 F 2 GLY A 408 ? VAL A 411 ? GLY A 408 VAL A 411 F 3 GLY A 403 ? VAL A 405 ? GLY A 403 VAL A 405 G 1 VAL A 487 ? GLN A 488 ? VAL A 487 GLN A 488 G 2 GLY A 491 ? LYS A 492 ? GLY A 491 LYS A 492 H 1 ALA A 652 ? ARG A 653 ? ALA A 652 ARG A 653 H 2 PHE A 672 ? TRP A 674 ? PHE A 672 TRP A 674 H 3 LEU A 678 ? THR A 681 ? LEU A 678 THR A 681 H 4 GLY A 726 ? ARG A 730 ? GLY A 726 ARG A 730 H 5 TRP A 700 ? ASP A 702 ? TRP A 700 ASP A 702 I 1 LYS A 690 ? VAL A 695 ? LYS A 690 VAL A 695 I 2 GLN A 714 ? GLU A 719 ? GLN A 714 GLU A 719 J 1 SER A 825 ? HIS A 831 ? SER A 825 HIS A 831 J 2 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 J 3 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 J 4 LEU A 785 ? THR A 792 ? LEU A 785 THR A 792 J 5 GLU A 763 ? TRP A 770 ? GLU A 763 TRP A 770 J 6 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 J 7 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 J 8 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 J 9 VAL A 850 ? THR A 854 ? VAL A 850 THR A 854 J 10 THR A 841 ? ASP A 845 ? THR A 841 ASP A 845 K 1 SER A 825 ? HIS A 831 ? SER A 825 HIS A 831 K 2 TYR A 864 ? ALA A 869 ? TYR A 864 ALA A 869 K 3 ARG A 795 ? SER A 803 ? ARG A 795 SER A 803 K 4 LEU A 785 ? THR A 792 ? LEU A 785 THR A 792 K 5 GLU A 763 ? TRP A 770 ? GLU A 763 TRP A 770 K 6 TYR A 733 ? GLN A 738 ? TYR A 733 GLN A 738 K 7 LEU A 752 ? ALA A 757 ? LEU A 752 ALA A 757 K 8 ALA A 812 ? LEU A 819 ? ALA A 812 LEU A 819 K 9 LEU A 858 ? LEU A 859 ? LEU A 858 LEU A 859 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N CYS A 32 ? N CYS A 32 O TYR A 45 ? O TYR A 45 B 1 2 N HIS A 53 ? N HIS A 53 O LYS A 70 ? O LYS A 70 B 2 3 N LEU A 69 ? N LEU A 69 O VAL A 85 ? O VAL A 85 B 3 4 N GLU A 90 ? N GLU A 90 O HIS A 98 ? O HIS A 98 B 4 5 N PHE A 99 ? N PHE A 99 O PHE A 262 ? O PHE A 262 B 5 6 O GLY A 267 ? O GLY A 267 N SER A 230 ? N SER A 230 B 6 7 O PHE A 231 ? O PHE A 231 N CYS A 222 ? N CYS A 222 B 7 8 O LEU A 221 ? O LEU A 221 N TYR A 178 ? N TYR A 178 C 1 2 N GLN A 130 ? N GLN A 130 O THR A 143 ? O THR A 143 C 2 3 N VAL A 142 ? N VAL A 142 O LEU A 151 ? O LEU A 151 D 1 2 N ALA A 162 ? N ALA A 162 O PHE A 165 ? O PHE A 165 D 2 3 N LEU A 166 ? N LEU A 166 O THR A 255 ? O THR A 255 D 3 4 O THR A 252 ? O THR A 252 N VAL A 244 ? N VAL A 244 D 4 5 O LEU A 245 ? O LEU A 245 N LYS A 195 ? N LYS A 195 E 1 2 O GLY A 569 ? O GLY A 569 N HIS A 538 ? N HIS A 538 E 2 3 O ALA A 537 ? O ALA A 537 N ILE A 523 ? N ILE A 523 E 3 4 O LEU A 524 ? O LEU A 524 N ILE A 442 ? N ILE A 442 E 4 5 O TRP A 441 ? O TRP A 441 N ILE A 363 ? N ILE A 363 E 5 6 O LYS A 360 ? O LYS A 360 N GLN A 324 ? N GLN A 324 E 6 7 O HIS A 325 ? O HIS A 325 N LEU A 296 ? N LEU A 296 E 7 8 N HIS A 295 ? N HIS A 295 O SER A 597 ? O SER A 597 E 8 9 O ARG A 598 ? O ARG A 598 N ILE A 572 ? N ILE A 572 F 1 2 N ILE A 369 ? N ILE A 369 O VAL A 411 ? O VAL A 411 F 2 3 O THR A 410 ? O THR A 410 N GLY A 403 ? N GLY A 403 G 1 2 N GLN A 488 ? N GLN A 488 O GLY A 491 ? O GLY A 491 H 1 2 N ARG A 653 ? N ARG A 653 O LEU A 673 ? O LEU A 673 H 2 3 N PHE A 672 ? N PHE A 672 O ILE A 680 ? O ILE A 680 H 3 4 N THR A 681 ? N THR A 681 O GLY A 726 ? O GLY A 726 H 4 5 O LEU A 729 ? O LEU A 729 N TYR A 701 ? N TYR A 701 I 1 2 N VAL A 691 ? N VAL A 691 O MET A 718 ? O MET A 718 J 1 2 N SER A 825 ? N SER A 825 O ALA A 869 ? O ALA A 869 J 2 3 O VAL A 866 ? O VAL A 866 N LEU A 796 ? N LEU A 796 J 3 4 O ASN A 799 ? O ASN A 799 N GLU A 788 ? N GLU A 788 J 4 5 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 J 5 6 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 J 6 7 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 J 7 8 N ILE A 756 ? N ILE A 756 O LYS A 817 ? O LYS A 817 J 8 9 N ILE A 816 ? N ILE A 816 O ILE A 853 ? O ILE A 853 J 9 10 O THR A 854 ? O THR A 854 N THR A 841 ? N THR A 841 K 1 2 N SER A 825 ? N SER A 825 O ALA A 869 ? O ALA A 869 K 2 3 O VAL A 866 ? O VAL A 866 N LEU A 796 ? N LEU A 796 K 3 4 O ASN A 799 ? O ASN A 799 N GLU A 788 ? N GLU A 788 K 4 5 O LEU A 785 ? O LEU A 785 N TRP A 770 ? N TRP A 770 K 5 6 O LYS A 765 ? O LYS A 765 N ILE A 734 ? N ILE A 734 K 6 7 N PHE A 735 ? N PHE A 735 O ILE A 755 ? O ILE A 755 K 7 8 N ILE A 756 ? N ILE A 756 O LYS A 817 ? O LYS A 817 K 8 9 N PHE A 813 ? N PHE A 813 O LEU A 858 ? O LEU A 858 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 19 'BINDING SITE FOR RESIDUE ACR A 1001' AC2 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE NAG A 2001' AC3 Software ? ? ? ? 10 'BINDING SITE FOR RESIDUE NAG X 2003' AC4 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG X 2004' AC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 2005' AC6 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE SO4 A 4001' AC7 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 3001' AC8 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE GOL A 3002' AC9 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE GOL A 3003' BC1 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE GOL A 3004' BC2 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE GOL A 3005' BC3 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE GOL A 3006' BC4 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL A 3007' BC5 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE GOL A 3008' BC6 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE GOL A 3009' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 19 ASP A 203 ? ASP A 203 . ? 1_555 ? 2 AC1 19 THR A 205 ? THR A 205 . ? 1_555 ? 3 AC1 19 ASN A 207 ? ASN A 207 . ? 1_555 ? 4 AC1 19 TYR A 299 ? TYR A 299 . ? 1_555 ? 5 AC1 19 ASP A 327 ? ASP A 327 . ? 1_555 ? 6 AC1 19 ILE A 328 ? ILE A 328 . ? 1_555 ? 7 AC1 19 ILE A 364 ? ILE A 364 . ? 1_555 ? 8 AC1 19 TRP A 441 ? TRP A 441 . ? 1_555 ? 9 AC1 19 ASP A 443 ? ASP A 443 . ? 1_555 ? 10 AC1 19 MET A 444 ? MET A 444 . ? 1_555 ? 11 AC1 19 ARG A 526 ? ARG A 526 . ? 1_555 ? 12 AC1 19 TRP A 539 ? TRP A 539 . ? 1_555 ? 13 AC1 19 ASP A 542 ? ASP A 542 . ? 1_555 ? 14 AC1 19 HIS A 600 ? HIS A 600 . ? 1_555 ? 15 AC1 19 HOH Q . ? HOH A 4081 . ? 1_555 ? 16 AC1 19 HOH Q . ? HOH A 4623 . ? 1_555 ? 17 AC1 19 HOH Q . ? HOH A 4625 . ? 1_555 ? 18 AC1 19 HOH Q . ? HOH A 4626 . ? 1_555 ? 19 AC1 19 HOH Q . ? HOH A 4627 . ? 1_555 ? 20 AC2 9 SER A 146 ? SER A 146 . ? 3_444 ? 21 AC2 9 ASN A 147 ? ASN A 147 . ? 3_444 ? 22 AC2 9 ASN A 148 ? ASN A 148 . ? 3_444 ? 23 AC2 9 GLN A 318 ? GLN A 318 . ? 1_555 ? 24 AC2 9 PRO A 740 ? PRO A 740 . ? 1_555 ? 25 AC2 9 ASN A 741 ? ASN A 741 . ? 1_555 ? 26 AC2 9 THR A 742 ? THR A 742 . ? 1_555 ? 27 AC2 9 ALA A 746 ? ALA A 746 . ? 1_555 ? 28 AC2 9 ASN A 750 ? ASN A 750 . ? 1_555 ? 29 AC3 10 LYS A 389 ? LYS A 389 . ? 1_555 ? 30 AC3 10 ASN A 393 ? ASN A 393 . ? 1_555 ? 31 AC3 10 GLY A 397 ? GLY A 397 . ? 1_555 ? 32 AC3 10 VAL A 398 ? VAL A 398 . ? 1_555 ? 33 AC3 10 VAL A 487 ? VAL A 487 . ? 1_555 ? 34 AC3 10 GLN A 488 ? GLN A 488 . ? 1_555 ? 35 AC3 10 HIS A 489 ? HIS A 489 . ? 1_555 ? 36 AC3 10 HOH Q . ? HOH A 4141 . ? 1_555 ? 37 AC3 10 HOH Q . ? HOH A 4622 . ? 1_555 ? 38 AC3 10 NAG P . ? NAG X 2004 . ? 1_555 ? 39 AC4 3 LYS A 389 ? LYS A 389 . ? 1_555 ? 40 AC4 3 HOH Q . ? HOH A 4518 . ? 1_555 ? 41 AC4 3 NAG O . ? NAG X 2003 . ? 1_555 ? 42 AC5 3 ASN A 207 ? ASN A 207 . ? 1_555 ? 43 AC5 3 GLY A 208 ? GLY A 208 . ? 1_555 ? 44 AC5 3 ASN A 209 ? ASN A 209 . ? 1_555 ? 45 AC6 6 SER A 126 ? SER A 126 . ? 1_555 ? 46 AC6 6 HIS A 625 ? HIS A 625 . ? 3_454 ? 47 AC6 6 ASN A 628 ? ASN A 628 . ? 3_454 ? 48 AC6 6 HOH Q . ? HOH A 4143 . ? 3_454 ? 49 AC6 6 HOH Q . ? HOH A 4151 . ? 3_454 ? 50 AC6 6 HOH Q . ? HOH A 4486 . ? 1_555 ? 51 AC7 5 ARG A 96 ? ARG A 96 . ? 1_555 ? 52 AC7 5 GLN A 117 ? GLN A 117 . ? 1_555 ? 53 AC7 5 PHE A 119 ? PHE A 119 . ? 1_555 ? 54 AC7 5 HOH Q . ? HOH A 4167 . ? 1_555 ? 55 AC7 5 HOH Q . ? HOH A 4352 . ? 1_555 ? 56 AC8 6 ALA A 285 ? ALA A 285 . ? 1_555 ? 57 AC8 6 ALA A 536 ? ALA A 536 . ? 1_555 ? 58 AC8 6 ALA A 537 ? ALA A 537 . ? 1_555 ? 59 AC8 6 HOH Q . ? HOH A 4009 . ? 1_555 ? 60 AC8 6 HOH Q . ? HOH A 4211 . ? 1_555 ? 61 AC8 6 HOH Q . ? HOH A 4621 . ? 1_555 ? 62 AC9 5 ASN A 306 ? ASN A 306 . ? 1_555 ? 63 AC9 5 GLU A 309 ? GLU A 309 . ? 1_555 ? 64 AC9 5 ARG A 313 ? ARG A 313 . ? 1_555 ? 65 AC9 5 ASP A 607 ? ASP A 607 . ? 1_555 ? 66 AC9 5 HOH Q . ? HOH A 4061 . ? 1_555 ? 67 BC1 8 LEU A 286 ? LEU A 286 . ? 1_555 ? 68 BC1 8 ARG A 520 ? ARG A 520 . ? 1_555 ? 69 BC1 8 HIS A 645 ? HIS A 645 . ? 1_555 ? 70 BC1 8 ASP A 777 ? ASP A 777 . ? 1_555 ? 71 BC1 8 THR A 778 ? THR A 778 . ? 1_555 ? 72 BC1 8 VAL A 779 ? VAL A 779 . ? 1_555 ? 73 BC1 8 ALA A 780 ? ALA A 780 . ? 1_555 ? 74 BC1 8 HOH Q . ? HOH A 4169 . ? 1_555 ? 75 BC2 8 TRP A 290 ? TRP A 290 . ? 1_555 ? 76 BC2 8 LYS A 360 ? LYS A 360 . ? 1_555 ? 77 BC2 8 ASP A 438 ? ASP A 438 . ? 1_555 ? 78 BC2 8 PHE A 516 ? PHE A 516 . ? 1_555 ? 79 BC2 8 SER A 521 ? SER A 521 . ? 1_555 ? 80 BC2 8 GLU A 774 ? GLU A 774 . ? 1_555 ? 81 BC2 8 HOH Q . ? HOH A 4069 . ? 1_555 ? 82 BC2 8 HOH Q . ? HOH A 4322 . ? 1_555 ? 83 BC3 7 PHE A 65 ? PHE A 65 . ? 1_555 ? 84 BC3 7 VAL A 131 ? VAL A 131 . ? 1_555 ? 85 BC3 7 GLU A 132 ? GLU A 132 . ? 1_555 ? 86 BC3 7 ILE A 133 ? ILE A 133 . ? 1_555 ? 87 BC3 7 THR A 843 ? THR A 843 . ? 3_454 ? 88 BC3 7 THR A 854 ? THR A 854 . ? 3_454 ? 89 BC3 7 HOH Q . ? HOH A 4174 . ? 3_454 ? 90 BC4 4 GLU A 582 ? GLU A 582 . ? 1_555 ? 91 BC4 4 ARG A 585 ? ARG A 585 . ? 1_555 ? 92 BC4 4 GLU A 689 ? GLU A 689 . ? 1_555 ? 93 BC4 4 GLY A 722 ? GLY A 722 . ? 1_555 ? 94 BC5 7 TYR A 626 ? TYR A 626 . ? 1_555 ? 95 BC5 7 ASP A 702 ? ASP A 702 . ? 1_555 ? 96 BC5 7 TYR A 703 ? TYR A 703 . ? 1_555 ? 97 BC5 7 GLU A 704 ? GLU A 704 . ? 1_555 ? 98 BC5 7 ILE A 725 ? ILE A 725 . ? 1_555 ? 99 BC5 7 GLY A 726 ? GLY A 726 . ? 1_555 ? 100 BC5 7 LEU A 727 ? LEU A 727 . ? 1_555 ? 101 BC6 4 GLU A 689 ? GLU A 689 . ? 1_555 ? 102 BC6 4 GLY A 722 ? GLY A 722 . ? 1_555 ? 103 BC6 4 HOH Q . ? HOH A 4517 . ? 1_555 ? 104 BC6 4 HOH Q . ? HOH A 4542 . ? 1_555 ? # _database_PDB_matrix.entry_id 2QMJ _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2QMJ _atom_sites.fract_transf_matrix[1][1] 0.011498 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009144 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.009152 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . VAL A 1 7 ? -33.555 35.392 9.718 1.00 45.90 ? 7 VAL A N 1 ATOM 2 C CA . VAL A 1 7 ? -34.363 34.832 8.589 1.00 44.85 ? 7 VAL A CA 1 ATOM 3 C C . VAL A 1 7 ? -35.327 33.727 9.040 1.00 43.39 ? 7 VAL A C 1 ATOM 4 O O . VAL A 1 7 ? -35.067 33.042 10.038 1.00 44.40 ? 7 VAL A O 1 ATOM 5 C CB . VAL A 1 7 ? -33.446 34.240 7.468 1.00 45.19 ? 7 VAL A CB 1 ATOM 6 C CG1 . VAL A 1 7 ? -32.987 35.340 6.491 1.00 47.06 ? 7 VAL A CG1 1 ATOM 7 C CG2 . VAL A 1 7 ? -32.259 33.499 8.060 1.00 45.60 ? 7 VAL A CG2 1 ATOM 8 N N . ASN A 1 8 ? -36.432 33.575 8.303 1.00 40.85 ? 8 ASN A N 1 ATOM 9 C CA . ASN A 1 8 ? -37.230 32.347 8.284 1.00 37.30 ? 8 ASN A CA 1 ATOM 10 C C . ASN A 1 8 ? -36.279 31.158 8.396 1.00 34.77 ? 8 ASN A C 1 ATOM 11 O O . ASN A 1 8 ? -35.303 31.070 7.652 1.00 33.35 ? 8 ASN A O 1 ATOM 12 C CB . ASN A 1 8 ? -38.006 32.286 6.970 1.00 38.31 ? 8 ASN A CB 1 ATOM 13 C CG . ASN A 1 8 ? -38.936 31.068 6.871 1.00 40.46 ? 8 ASN A CG 1 ATOM 14 O OD1 . ASN A 1 8 ? -38.489 29.934 6.805 1.00 40.02 ? 8 ASN A OD1 1 ATOM 15 N ND2 . ASN A 1 8 ? -40.246 31.317 6.848 1.00 46.13 ? 8 ASN A ND2 1 ATOM 16 N N . GLU A 1 9 ? -36.534 30.258 9.338 1.00 32.23 ? 9 GLU A N 1 ATOM 17 C CA . GLU A 1 9 ? -35.607 29.158 9.562 1.00 31.17 ? 9 GLU A CA 1 ATOM 18 C C . GLU A 1 9 ? -35.413 28.213 8.362 1.00 28.06 ? 9 GLU A C 1 ATOM 19 O O . GLU A 1 9 ? -34.342 27.623 8.211 1.00 26.66 ? 9 GLU A O 1 ATOM 20 C CB . GLU A 1 9 ? -35.929 28.397 10.860 1.00 32.05 ? 9 GLU A CB 1 ATOM 21 C CG . GLU A 1 9 ? -37.280 27.723 10.936 1.00 33.85 ? 9 GLU A CG 1 ATOM 22 C CD . GLU A 1 9 ? -37.509 27.070 12.306 1.00 35.83 ? 9 GLU A CD 1 ATOM 23 O OE1 . GLU A 1 9 ? -37.419 27.768 13.353 1.00 42.04 ? 9 GLU A OE1 1 ATOM 24 O OE2 . GLU A 1 9 ? -37.779 25.840 12.343 1.00 44.06 ? 9 GLU A OE2 1 ATOM 25 N N . LEU A 1 10 ? -36.417 28.092 7.489 1.00 24.70 ? 10 LEU A N 1 ATOM 26 C CA . LEU A 1 10 ? -36.288 27.220 6.308 1.00 23.22 ? 10 LEU A CA 1 ATOM 27 C C . LEU A 1 10 ? -35.288 27.783 5.308 1.00 21.73 ? 10 LEU A C 1 ATOM 28 O O . LEU A 1 10 ? -34.803 27.058 4.431 1.00 21.53 ? 10 LEU A O 1 ATOM 29 C CB . LEU A 1 10 ? -37.640 27.010 5.609 1.00 22.64 ? 10 LEU A CB 1 ATOM 30 C CG . LEU A 1 10 ? -38.777 26.443 6.454 1.00 23.95 ? 10 LEU A CG 1 ATOM 31 C CD1 . LEU A 1 10 ? -40.014 26.207 5.571 1.00 26.10 ? 10 LEU A CD1 1 ATOM 32 C CD2 . LEU A 1 10 ? -38.374 25.155 7.175 1.00 23.96 ? 10 LEU A CD2 1 ATOM 33 N N . GLU A 1 11 ? -34.978 29.071 5.445 1.00 20.47 ? 11 GLU A N 1 ATOM 34 C CA . GLU A 1 11 ? -34.047 29.746 4.540 1.00 21.54 ? 11 GLU A CA 1 ATOM 35 C C . GLU A 1 11 ? -32.623 29.808 5.082 1.00 20.15 ? 11 GLU A C 1 ATOM 36 O O . GLU A 1 11 ? -31.733 30.358 4.420 1.00 19.05 ? 11 GLU A O 1 ATOM 37 C CB . GLU A 1 11 ? -34.507 31.143 4.182 1.00 21.41 ? 11 GLU A CB 1 ATOM 38 C CG . GLU A 1 11 ? -35.832 31.156 3.371 1.00 25.94 ? 11 GLU A CG 1 ATOM 39 C CD . GLU A 1 11 ? -36.392 32.559 3.109 1.00 28.25 ? 11 GLU A CD 1 ATOM 40 O OE1 . GLU A 1 11 ? -35.638 33.567 3.183 1.00 36.76 ? 11 GLU A OE1 1 ATOM 41 O OE2 . GLU A 1 11 ? -37.628 32.643 2.822 1.00 36.78 ? 11 GLU A OE2 1 ATOM 42 N N . ARG A 1 12 ? -32.402 29.248 6.267 1.00 19.18 ? 12 ARG A N 1 ATOM 43 C CA . ARG A 1 12 ? -31.025 29.281 6.816 1.00 19.60 ? 12 ARG A CA 1 ATOM 44 C C . ARG A 1 12 ? -30.078 28.384 6.047 1.00 18.72 ? 12 ARG A C 1 ATOM 45 O O . ARG A 1 12 ? -30.403 27.235 5.771 1.00 19.34 ? 12 ARG A O 1 ATOM 46 C CB . ARG A 1 12 ? -31.028 28.876 8.273 1.00 19.78 ? 12 ARG A CB 1 ATOM 47 C CG . ARG A 1 12 ? -31.658 29.919 9.146 1.00 23.73 ? 12 ARG A CG 1 ATOM 48 C CD . ARG A 1 12 ? -31.897 29.291 10.474 1.00 28.27 ? 12 ARG A CD 1 ATOM 49 N NE . ARG A 1 12 ? -32.759 30.077 11.329 1.00 33.50 ? 12 ARG A NE 1 ATOM 50 C CZ . ARG A 1 12 ? -32.887 29.847 12.635 1.00 36.79 ? 12 ARG A CZ 1 ATOM 51 N NH1 . ARG A 1 12 ? -32.179 28.881 13.241 1.00 37.33 ? 12 ARG A NH1 1 ATOM 52 N NH2 . ARG A 1 12 ? -33.721 30.591 13.327 1.00 38.58 ? 12 ARG A NH2 1 ATOM 53 N N . ILE A 1 13 ? -28.892 28.890 5.742 1.00 17.60 ? 13 ILE A N 1 ATOM 54 C CA . ILE A 1 13 ? -27.919 28.146 4.951 1.00 17.21 ? 13 ILE A CA 1 ATOM 55 C C . ILE A 1 13 ? -26.823 27.755 5.949 1.00 17.38 ? 13 ILE A C 1 ATOM 56 O O . ILE A 1 13 ? -26.250 28.617 6.595 1.00 16.09 ? 13 ILE A O 1 ATOM 57 C CB . ILE A 1 13 ? -27.342 29.011 3.830 1.00 17.07 ? 13 ILE A CB 1 ATOM 58 C CG1 . ILE A 1 13 ? -28.450 29.438 2.860 1.00 17.02 ? 13 ILE A CG1 1 ATOM 59 C CG2 . ILE A 1 13 ? -26.295 28.263 3.007 1.00 16.78 ? 13 ILE A CG2 1 ATOM 60 C CD1 . ILE A 1 13 ? -29.098 28.266 2.097 1.00 16.52 ? 13 ILE A CD1 1 ATOM 61 N N . ASN A 1 14 ? -26.592 26.458 6.076 1.00 16.54 ? 14 ASN A N 1 ATOM 62 C CA . ASN A 1 14 ? -25.848 25.896 7.173 1.00 16.34 ? 14 ASN A CA 1 ATOM 63 C C . ASN A 1 14 ? -24.382 26.316 7.012 1.00 16.18 ? 14 ASN A C 1 ATOM 64 O O . ASN A 1 14 ? -23.796 26.097 5.968 1.00 15.44 ? 14 ASN A O 1 ATOM 65 C CB . ASN A 1 14 ? -26.000 24.383 7.124 1.00 16.42 ? 14 ASN A CB 1 ATOM 66 C CG . ASN A 1 14 ? -25.188 23.651 8.226 1.00 19.16 ? 14 ASN A CG 1 ATOM 67 O OD1 . ASN A 1 14 ? -24.659 24.268 9.148 1.00 18.97 ? 14 ASN A OD1 1 ATOM 68 N ND2 . ASN A 1 14 ? -25.070 22.336 8.088 1.00 20.07 ? 14 ASN A ND2 1 ATOM 69 N N . CYS A 1 15 ? -23.832 26.931 8.059 1.00 18.20 ? 15 CYS A N 1 ATOM 70 C CA . CYS A 1 15 ? -22.444 27.418 8.111 1.00 19.29 ? 15 CYS A CA 1 ATOM 71 C C . CYS A 1 15 ? -21.483 26.380 8.738 1.00 19.06 ? 15 CYS A C 1 ATOM 72 O O . CYS A 1 15 ? -20.232 26.560 8.768 1.00 18.26 ? 15 CYS A O 1 ATOM 73 C CB . CYS A 1 15 ? -22.435 28.749 8.933 1.00 20.41 ? 15 CYS A CB 1 ATOM 74 S SG . CYS A 1 15 ? -20.788 29.412 9.270 1.00 24.87 ? 15 CYS A SG 1 ATOM 75 N N . ILE A 1 16 ? -22.061 25.307 9.268 1.00 18.34 ? 16 ILE A N 1 ATOM 76 C CA . ILE A 1 16 ? -21.244 24.255 9.878 1.00 18.84 ? 16 ILE A CA 1 ATOM 77 C C . ILE A 1 16 ? -21.647 22.908 9.266 1.00 20.06 ? 16 ILE A C 1 ATOM 78 O O . ILE A 1 16 ? -22.297 22.089 9.918 1.00 20.28 ? 16 ILE A O 1 ATOM 79 C CB . ILE A 1 16 ? -21.298 24.229 11.428 1.00 17.91 ? 16 ILE A CB 1 ATOM 80 C CG1 . ILE A 1 16 ? -20.879 25.555 12.033 1.00 16.77 ? 16 ILE A CG1 1 ATOM 81 C CG2 . ILE A 1 16 ? -20.316 23.188 11.977 1.00 19.32 ? 16 ILE A CG2 1 ATOM 82 C CD1 . ILE A 1 16 ? -21.068 25.611 13.567 1.00 17.43 ? 16 ILE A CD1 1 ATOM 83 N N . PRO A 1 17 ? -21.261 22.687 8.005 1.00 20.86 ? 17 PRO A N 1 ATOM 84 C CA . PRO A 1 17 ? -21.585 21.439 7.329 1.00 22.52 ? 17 PRO A CA 1 ATOM 85 C C . PRO A 1 17 ? -20.701 20.257 7.758 1.00 24.30 ? 17 PRO A C 1 ATOM 86 O O . PRO A 1 17 ? -21.044 19.106 7.453 1.00 25.28 ? 17 PRO A O 1 ATOM 87 C CB . PRO A 1 17 ? -21.293 21.785 5.872 1.00 22.29 ? 17 PRO A CB 1 ATOM 88 C CG . PRO A 1 17 ? -20.109 22.717 5.964 1.00 23.16 ? 17 PRO A CG 1 ATOM 89 C CD . PRO A 1 17 ? -20.504 23.595 7.122 1.00 21.65 ? 17 PRO A CD 1 ATOM 90 N N . ASP A 1 18 ? -19.602 20.547 8.469 1.00 24.03 ? 18 ASP A N 1 ATOM 91 C CA . ASP A 1 18 ? -18.467 19.640 8.639 1.00 26.04 ? 18 ASP A CA 1 ATOM 92 C C . ASP A 1 18 ? -18.344 19.001 10.018 1.00 27.51 ? 18 ASP A C 1 ATOM 93 O O . ASP A 1 18 ? -17.422 18.190 10.237 1.00 28.11 ? 18 ASP A O 1 ATOM 94 C CB . ASP A 1 18 ? -17.159 20.390 8.378 1.00 25.44 ? 18 ASP A CB 1 ATOM 95 C CG . ASP A 1 18 ? -17.049 21.722 9.173 1.00 27.45 ? 18 ASP A CG 1 ATOM 96 O OD1 . ASP A 1 18 ? -18.056 22.455 9.295 1.00 23.39 ? 18 ASP A OD1 1 ATOM 97 O OD2 . ASP A 1 18 ? -15.927 22.067 9.666 1.00 27.19 ? 18 ASP A OD2 1 ATOM 98 N N . GLN A 1 19 ? -19.203 19.408 10.953 1.00 27.82 ? 19 GLN A N 1 ATOM 99 C CA . GLN A 1 19 ? -19.101 18.967 12.353 1.00 29.07 ? 19 GLN A CA 1 ATOM 100 C C . GLN A 1 19 ? -20.396 19.219 13.121 1.00 29.45 ? 19 GLN A C 1 ATOM 101 O O . GLN A 1 19 ? -21.274 19.909 12.607 1.00 28.99 ? 19 GLN A O 1 ATOM 102 C CB . GLN A 1 19 ? -17.892 19.634 13.031 1.00 29.62 ? 19 GLN A CB 1 ATOM 103 C CG . GLN A 1 19 ? -18.008 21.092 13.255 1.00 29.55 ? 19 GLN A CG 1 ATOM 104 C CD . GLN A 1 19 ? -16.666 21.744 13.519 1.00 32.70 ? 19 GLN A CD 1 ATOM 105 O OE1 . GLN A 1 19 ? -15.647 21.378 12.937 1.00 37.04 ? 19 GLN A OE1 1 ATOM 106 N NE2 . GLN A 1 19 ? -16.663 22.729 14.388 1.00 31.45 ? 19 GLN A NE2 1 ATOM 107 N N . PRO A 1 20 ? -20.555 18.622 14.342 1.00 29.83 ? 20 PRO A N 1 ATOM 108 C CA . PRO A 1 20 ? -21.754 19.020 15.116 1.00 29.50 ? 20 PRO A CA 1 ATOM 109 C C . PRO A 1 20 ? -21.661 20.512 15.500 1.00 27.88 ? 20 PRO A C 1 ATOM 110 O O . PRO A 1 20 ? -20.588 20.941 15.912 1.00 28.61 ? 20 PRO A O 1 ATOM 111 C CB . PRO A 1 20 ? -21.708 18.119 16.364 1.00 29.05 ? 20 PRO A CB 1 ATOM 112 C CG . PRO A 1 20 ? -20.242 17.661 16.473 1.00 30.37 ? 20 PRO A CG 1 ATOM 113 C CD . PRO A 1 20 ? -19.746 17.589 15.038 1.00 30.41 ? 20 PRO A CD 1 ATOM 114 N N . PRO A 1 21 ? -22.757 21.277 15.347 1.00 27.16 ? 21 PRO A N 1 ATOM 115 C CA . PRO A 1 21 ? -22.751 22.751 15.473 1.00 26.17 ? 21 PRO A CA 1 ATOM 116 C C . PRO A 1 21 ? -22.415 23.200 16.903 1.00 25.57 ? 21 PRO A C 1 ATOM 117 O O . PRO A 1 21 ? -23.004 22.699 17.868 1.00 25.53 ? 21 PRO A O 1 ATOM 118 C CB . PRO A 1 21 ? -24.191 23.160 15.097 1.00 25.97 ? 21 PRO A CB 1 ATOM 119 C CG . PRO A 1 21 ? -25.003 21.956 15.355 1.00 27.08 ? 21 PRO A CG 1 ATOM 120 C CD . PRO A 1 21 ? -24.106 20.765 15.040 1.00 27.31 ? 21 PRO A CD 1 ATOM 121 N N . THR A 1 22 ? -21.454 24.111 17.042 1.00 24.31 ? 22 THR A N 1 ATOM 122 C CA . THR A 1 22 ? -21.198 24.714 18.335 1.00 23.35 ? 22 THR A CA 1 ATOM 123 C C . THR A 1 22 ? -21.225 26.242 18.204 1.00 23.23 ? 22 THR A C 1 ATOM 124 O O . THR A 1 22 ? -20.873 26.777 17.159 1.00 23.32 ? 22 THR A O 1 ATOM 125 C CB . THR A 1 22 ? -19.835 24.242 18.932 1.00 23.14 ? 22 THR A CB 1 ATOM 126 O OG1 . THR A 1 22 ? -18.768 24.657 18.095 1.00 24.85 ? 22 THR A OG1 1 ATOM 127 C CG2 . THR A 1 22 ? -19.760 22.723 19.045 1.00 22.92 ? 22 THR A CG2 1 ATOM 128 N N . LYS A 1 23 ? -21.610 26.932 19.264 1.00 23.55 ? 23 LYS A N 1 ATOM 129 C CA . LYS A 1 23 ? -21.518 28.388 19.275 1.00 24.57 ? 23 LYS A CA 1 ATOM 130 C C . LYS A 1 23 ? -20.070 28.832 19.072 1.00 23.85 ? 23 LYS A C 1 ATOM 131 O O . LYS A 1 23 ? -19.829 29.813 18.382 1.00 23.01 ? 23 LYS A O 1 ATOM 132 C CB . LYS A 1 23 ? -22.112 29.002 20.558 1.00 25.65 ? 23 LYS A CB 1 ATOM 133 C CG . LYS A 1 23 ? -22.264 30.545 20.470 1.00 27.20 ? 23 LYS A CG 1 ATOM 134 C CD . LYS A 1 23 ? -22.687 31.198 21.784 1.00 28.16 ? 23 LYS A CD 1 ATOM 135 C CE . LYS A 1 23 ? -23.101 32.695 21.563 1.00 31.00 ? 23 LYS A CE 1 ATOM 136 N NZ . LYS A 1 23 ? -22.057 33.561 20.899 1.00 33.62 ? 23 LYS A NZ 1 ATOM 137 N N . ALA A 1 24 ? -19.093 28.124 19.640 1.00 23.50 ? 24 ALA A N 1 ATOM 138 C CA . ALA A 1 24 ? -17.711 28.550 19.504 1.00 24.06 ? 24 ALA A CA 1 ATOM 139 C C . ALA A 1 24 ? -17.272 28.567 18.039 1.00 24.48 ? 24 ALA A C 1 ATOM 140 O O . ALA A 1 24 ? -16.683 29.552 17.561 1.00 25.38 ? 24 ALA A O 1 ATOM 141 C CB . ALA A 1 24 ? -16.758 27.665 20.362 1.00 25.09 ? 24 ALA A CB 1 ATOM 142 N N . THR A 1 25 ? -17.561 27.491 17.305 1.00 23.35 ? 25 THR A N 1 ATOM 143 C CA . THR A 1 25 ? -17.232 27.459 15.875 1.00 23.74 ? 25 THR A CA 1 ATOM 144 C C . THR A 1 25 ? -18.058 28.509 15.109 1.00 22.99 ? 25 THR A C 1 ATOM 145 O O . THR A 1 25 ? -17.549 29.172 14.229 1.00 22.31 ? 25 THR A O 1 ATOM 146 C CB . THR A 1 25 ? -17.457 26.065 15.282 1.00 23.53 ? 25 THR A CB 1 ATOM 147 O OG1 . THR A 1 25 ? -16.501 25.161 15.844 1.00 26.26 ? 25 THR A OG1 1 ATOM 148 C CG2 . THR A 1 25 ? -17.267 26.054 13.762 1.00 22.56 ? 25 THR A CG2 1 ATOM 149 N N . CYS A 1 26 ? -19.325 28.646 15.466 1.00 24.40 ? 26 CYS A N 1 ATOM 150 C CA . CYS A 1 26 ? -20.188 29.628 14.820 1.00 24.80 ? 26 CYS A CA 1 ATOM 151 C C . CYS A 1 26 ? -19.580 31.032 14.925 1.00 25.10 ? 26 CYS A C 1 ATOM 152 O O . CYS A 1 26 ? -19.404 31.737 13.908 1.00 24.09 ? 26 CYS A O 1 ATOM 153 C CB . CYS A 1 26 ? -21.558 29.572 15.468 1.00 25.46 ? 26 CYS A CB 1 ATOM 154 S SG . CYS A 1 26 ? -22.736 30.662 14.641 1.00 30.48 ? 26 CYS A SG 1 ATOM 155 N N . ASP A 1 27 ? -19.191 31.411 16.148 1.00 25.36 ? 27 ASP A N 1 ATOM 156 C CA . ASP A 1 27 ? -18.568 32.726 16.400 1.00 26.02 ? 27 ASP A CA 1 ATOM 157 C C . ASP A 1 27 ? -17.270 32.905 15.619 1.00 26.54 ? 27 ASP A C 1 ATOM 158 O O . ASP A 1 27 ? -17.071 33.946 14.998 1.00 27.52 ? 27 ASP A O 1 ATOM 159 C CB . ASP A 1 27 ? -18.309 32.936 17.888 1.00 25.86 ? 27 ASP A CB 1 ATOM 160 C CG . ASP A 1 27 ? -19.591 33.106 18.702 1.00 29.03 ? 27 ASP A CG 1 ATOM 161 O OD1 . ASP A 1 27 ? -20.692 33.305 18.142 1.00 28.47 ? 27 ASP A OD1 1 ATOM 162 O OD2 . ASP A 1 27 ? -19.507 33.022 19.940 1.00 34.17 ? 27 ASP A OD2 1 ATOM 163 N N . GLN A 1 28 ? -16.387 31.906 15.630 1.00 26.27 ? 28 GLN A N 1 ATOM 164 C CA . GLN A 1 28 ? -15.121 31.993 14.865 1.00 26.01 ? 28 GLN A CA 1 ATOM 165 C C . GLN A 1 28 ? -15.357 32.211 13.364 1.00 25.62 ? 28 GLN A C 1 ATOM 166 O O . GLN A 1 28 ? -14.553 32.859 12.671 1.00 24.40 ? 28 GLN A O 1 ATOM 167 C CB . GLN A 1 28 ? -14.247 30.730 15.097 1.00 26.66 ? 28 GLN A CB 1 ATOM 168 C CG . GLN A 1 28 ? -12.970 30.644 14.218 1.00 28.56 ? 28 GLN A CG 1 ATOM 169 C CD . GLN A 1 28 ? -11.927 31.734 14.551 1.00 35.58 ? 28 GLN A CD 1 ATOM 170 O OE1 . GLN A 1 28 ? -12.023 32.409 15.587 1.00 39.16 ? 28 GLN A OE1 1 ATOM 171 N NE2 . GLN A 1 28 ? -10.929 31.900 13.678 1.00 34.31 ? 28 GLN A NE2 1 ATOM 172 N N . ARG A 1 29 ? -16.471 31.680 12.865 1.00 24.85 ? 29 ARG A N 1 ATOM 173 C CA . ARG A 1 29 ? -16.736 31.727 11.433 1.00 24.70 ? 29 ARG A CA 1 ATOM 174 C C . ARG A 1 29 ? -17.545 32.966 11.046 1.00 24.94 ? 29 ARG A C 1 ATOM 175 O O . ARG A 1 29 ? -17.774 33.222 9.858 1.00 24.08 ? 29 ARG A O 1 ATOM 176 C CB . ARG A 1 29 ? -17.451 30.442 10.997 1.00 24.98 ? 29 ARG A CB 1 ATOM 177 C CG . ARG A 1 29 ? -16.613 29.216 11.130 1.00 24.61 ? 29 ARG A CG 1 ATOM 178 C CD . ARG A 1 29 ? -17.268 27.994 10.513 1.00 26.80 ? 29 ARG A CD 1 ATOM 179 N NE . ARG A 1 29 ? -16.344 26.887 10.703 1.00 26.40 ? 29 ARG A NE 1 ATOM 180 C CZ . ARG A 1 29 ? -16.579 25.634 10.378 1.00 25.07 ? 29 ARG A CZ 1 ATOM 181 N NH1 . ARG A 1 29 ? -17.728 25.281 9.810 1.00 19.27 ? 29 ARG A NH1 1 ATOM 182 N NH2 . ARG A 1 29 ? -15.643 24.736 10.637 1.00 24.66 ? 29 ARG A NH2 1 ATOM 183 N N . GLY A 1 30 ? -17.953 33.744 12.050 1.00 23.95 ? 30 GLY A N 1 ATOM 184 C CA . GLY A 1 30 ? -18.685 34.968 11.814 1.00 24.62 ? 30 GLY A CA 1 ATOM 185 C C . GLY A 1 30 ? -20.110 34.667 11.382 1.00 24.59 ? 30 GLY A C 1 ATOM 186 O O . GLY A 1 30 ? -20.712 35.459 10.662 1.00 25.49 ? 30 GLY A O 1 ATOM 187 N N . CYS A 1 31 ? -20.664 33.546 11.835 1.00 23.75 ? 31 CYS A N 1 ATOM 188 C CA . CYS A 1 31 ? -22.010 33.140 11.431 1.00 23.39 ? 31 CYS A CA 1 ATOM 189 C C . CYS A 1 31 ? -23.043 33.426 12.504 1.00 23.65 ? 31 CYS A C 1 ATOM 190 O O . CYS A 1 31 ? -22.720 34.006 13.537 1.00 23.00 ? 31 CYS A O 1 ATOM 191 C CB . CYS A 1 31 ? -22.010 31.664 11.019 1.00 23.92 ? 31 CYS A CB 1 ATOM 192 S SG . CYS A 1 31 ? -21.146 31.436 9.452 1.00 24.55 ? 31 CYS A SG 1 ATOM 193 N N . CYS A 1 32 ? -24.295 33.075 12.239 1.00 23.41 ? 32 CYS A N 1 ATOM 194 C CA . CYS A 1 32 ? -25.398 33.349 13.147 1.00 24.45 ? 32 CYS A CA 1 ATOM 195 C C . CYS A 1 32 ? -25.719 32.100 13.950 1.00 24.63 ? 32 CYS A C 1 ATOM 196 O O . CYS A 1 32 ? -25.688 31.002 13.399 1.00 23.10 ? 32 CYS A O 1 ATOM 197 C CB . CYS A 1 32 ? -26.630 33.742 12.346 1.00 24.80 ? 32 CYS A CB 1 ATOM 198 S SG . CYS A 1 32 ? -26.335 35.132 11.289 1.00 28.59 ? 32 CYS A SG 1 ATOM 199 N N . TRP A 1 33 ? -26.031 32.264 15.236 1.00 25.81 ? 33 TRP A N 1 ATOM 200 C CA . TRP A 1 33 ? -26.322 31.140 16.144 1.00 27.54 ? 33 TRP A CA 1 ATOM 201 C C . TRP A 1 33 ? -27.762 31.170 16.686 1.00 28.98 ? 33 TRP A C 1 ATOM 202 O O . TRP A 1 33 ? -28.152 32.128 17.341 1.00 28.50 ? 33 TRP A O 1 ATOM 203 C CB . TRP A 1 33 ? -25.331 31.148 17.313 1.00 28.41 ? 33 TRP A CB 1 ATOM 204 C CG . TRP A 1 33 ? -25.524 30.023 18.295 1.00 29.68 ? 33 TRP A CG 1 ATOM 205 C CD1 . TRP A 1 33 ? -26.077 30.114 19.545 1.00 30.33 ? 33 TRP A CD1 1 ATOM 206 C CD2 . TRP A 1 33 ? -25.172 28.636 18.107 1.00 29.66 ? 33 TRP A CD2 1 ATOM 207 N NE1 . TRP A 1 33 ? -26.079 28.874 20.147 1.00 28.97 ? 33 TRP A NE1 1 ATOM 208 C CE2 . TRP A 1 33 ? -25.536 27.950 19.289 1.00 29.80 ? 33 TRP A CE2 1 ATOM 209 C CE3 . TRP A 1 33 ? -24.590 27.912 17.055 1.00 28.19 ? 33 TRP A CE3 1 ATOM 210 C CZ2 . TRP A 1 33 ? -25.334 26.573 19.450 1.00 29.13 ? 33 TRP A CZ2 1 ATOM 211 C CZ3 . TRP A 1 33 ? -24.386 26.556 17.216 1.00 29.65 ? 33 TRP A CZ3 1 ATOM 212 C CH2 . TRP A 1 33 ? -24.763 25.895 18.412 1.00 29.92 ? 33 TRP A CH2 1 ATOM 213 N N . ASN A 1 34 ? -28.546 30.123 16.436 1.00 29.90 ? 34 ASN A N 1 ATOM 214 C CA . ASN A 1 34 ? -29.914 30.050 16.969 1.00 32.60 ? 34 ASN A CA 1 ATOM 215 C C . ASN A 1 34 ? -30.319 28.586 17.045 1.00 34.51 ? 34 ASN A C 1 ATOM 216 O O . ASN A 1 34 ? -30.874 28.047 16.088 1.00 34.13 ? 34 ASN A O 1 ATOM 217 C CB . ASN A 1 34 ? -30.885 30.884 16.108 1.00 32.35 ? 34 ASN A CB 1 ATOM 218 C CG . ASN A 1 34 ? -32.363 30.825 16.598 1.00 35.29 ? 34 ASN A CG 1 ATOM 219 O OD1 . ASN A 1 34 ? -32.759 29.971 17.387 1.00 37.48 ? 34 ASN A OD1 1 ATOM 220 N ND2 . ASN A 1 34 ? -33.167 31.739 16.097 1.00 35.73 ? 34 ASN A ND2 1 ATOM 221 N N . PRO A 1 35 ? -29.999 27.915 18.173 1.00 37.01 ? 35 PRO A N 1 ATOM 222 C CA . PRO A 1 35 ? -30.353 26.511 18.297 1.00 38.90 ? 35 PRO A CA 1 ATOM 223 C C . PRO A 1 35 ? -31.842 26.229 18.402 1.00 41.11 ? 35 PRO A C 1 ATOM 224 O O . PRO A 1 35 ? -32.210 25.073 18.324 1.00 42.91 ? 35 PRO A O 1 ATOM 225 C CB . PRO A 1 35 ? -29.655 26.063 19.600 1.00 38.34 ? 35 PRO A CB 1 ATOM 226 C CG . PRO A 1 35 ? -28.719 27.113 19.926 1.00 37.70 ? 35 PRO A CG 1 ATOM 227 C CD . PRO A 1 35 ? -29.270 28.388 19.361 1.00 37.08 ? 35 PRO A CD 1 ATOM 228 N N . GLN A 1 36 ? -32.699 27.232 18.539 1.00 43.15 ? 36 GLN A N 1 ATOM 229 C CA . GLN A 1 36 ? -34.107 26.947 18.888 1.00 45.88 ? 36 GLN A CA 1 ATOM 230 C C . GLN A 1 36 ? -35.013 26.481 17.723 1.00 46.72 ? 36 GLN A C 1 ATOM 231 O O . GLN A 1 36 ? -36.249 26.470 17.868 1.00 47.41 ? 36 GLN A O 1 ATOM 232 C CB . GLN A 1 36 ? -34.774 28.114 19.661 1.00 46.40 ? 36 GLN A CB 1 ATOM 233 C CG . GLN A 1 36 ? -33.816 29.110 20.366 1.00 49.93 ? 36 GLN A CG 1 ATOM 234 C CD . GLN A 1 36 ? -33.027 28.495 21.514 1.00 53.42 ? 36 GLN A CD 1 ATOM 235 O OE1 . GLN A 1 36 ? -33.531 27.630 22.236 1.00 56.53 ? 36 GLN A OE1 1 ATOM 236 N NE2 . GLN A 1 36 ? -31.783 28.943 21.690 1.00 53.89 ? 36 GLN A NE2 1 ATOM 237 N N . GLY A 1 37 ? -34.419 26.072 16.596 1.00 47.11 ? 37 GLY A N 1 ATOM 238 C CA . GLY A 1 37 ? -35.204 25.587 15.445 1.00 46.90 ? 37 GLY A CA 1 ATOM 239 C C . GLY A 1 37 ? -35.828 24.194 15.601 1.00 46.87 ? 37 GLY A C 1 ATOM 240 O O . GLY A 1 37 ? -35.723 23.559 16.672 1.00 47.88 ? 37 GLY A O 1 ATOM 241 N N . ALA A 1 38 ? -36.484 23.724 14.530 1.00 45.48 ? 38 ALA A N 1 ATOM 242 C CA . ALA A 1 38 ? -36.973 22.334 14.409 1.00 43.60 ? 38 ALA A CA 1 ATOM 243 C C . ALA A 1 38 ? -35.854 21.373 13.982 1.00 42.31 ? 38 ALA A C 1 ATOM 244 O O . ALA A 1 38 ? -34.745 21.814 13.661 1.00 41.54 ? 38 ALA A O 1 ATOM 245 C CB . ALA A 1 38 ? -38.102 22.284 13.412 1.00 43.78 ? 38 ALA A CB 1 ATOM 246 N N . VAL A 1 39 ? -36.141 20.069 13.957 1.00 40.06 ? 39 VAL A N 1 ATOM 247 C CA . VAL A 1 39 ? -35.125 19.085 13.534 1.00 38.42 ? 39 VAL A CA 1 ATOM 248 C C . VAL A 1 39 ? -34.482 19.449 12.174 1.00 36.22 ? 39 VAL A C 1 ATOM 249 O O . VAL A 1 39 ? -35.177 19.857 11.238 1.00 35.60 ? 39 VAL A O 1 ATOM 250 C CB . VAL A 1 39 ? -35.662 17.614 13.539 1.00 38.48 ? 39 VAL A CB 1 ATOM 251 C CG1 . VAL A 1 39 ? -36.879 17.429 12.589 1.00 39.55 ? 39 VAL A CG1 1 ATOM 252 C CG2 . VAL A 1 39 ? -34.533 16.627 13.226 1.00 39.05 ? 39 VAL A CG2 1 ATOM 253 N N . SER A 1 40 ? -33.157 19.356 12.111 1.00 33.67 ? 40 SER A N 1 ATOM 254 C CA . SER A 1 40 ? -32.375 19.560 10.865 1.00 32.23 ? 40 SER A CA 1 ATOM 255 C C . SER A 1 40 ? -32.247 21.019 10.449 1.00 30.04 ? 40 SER A C 1 ATOM 256 O O . SER A 1 40 ? -31.425 21.324 9.593 1.00 30.23 ? 40 SER A O 1 ATOM 257 C CB . SER A 1 40 ? -32.917 18.749 9.669 1.00 32.59 ? 40 SER A CB 1 ATOM 258 O OG . SER A 1 40 ? -33.209 17.415 10.023 1.00 33.29 ? 40 SER A OG 1 ATOM 259 N N . VAL A 1 41 ? -33.016 21.918 11.064 1.00 27.62 ? 41 VAL A N 1 ATOM 260 C CA . VAL A 1 41 ? -32.795 23.362 10.848 1.00 26.13 ? 41 VAL A CA 1 ATOM 261 C C . VAL A 1 41 ? -31.404 23.704 11.414 1.00 25.10 ? 41 VAL A C 1 ATOM 262 O O . VAL A 1 41 ? -31.126 23.399 12.580 1.00 25.31 ? 41 VAL A O 1 ATOM 263 C CB . VAL A 1 41 ? -33.876 24.221 11.512 1.00 26.53 ? 41 VAL A CB 1 ATOM 264 C CG1 . VAL A 1 41 ? -33.540 25.717 11.391 1.00 25.23 ? 41 VAL A CG1 1 ATOM 265 C CG2 . VAL A 1 41 ? -35.215 23.927 10.879 1.00 25.62 ? 41 VAL A CG2 1 ATOM 266 N N . PRO A 1 42 ? -30.520 24.290 10.587 1.00 23.53 ? 42 PRO A N 1 ATOM 267 C CA . PRO A 1 42 ? -29.151 24.511 11.048 1.00 24.03 ? 42 PRO A CA 1 ATOM 268 C C . PRO A 1 42 ? -29.113 25.475 12.224 1.00 24.05 ? 42 PRO A C 1 ATOM 269 O O . PRO A 1 42 ? -29.735 26.527 12.186 1.00 24.16 ? 42 PRO A O 1 ATOM 270 C CB . PRO A 1 42 ? -28.435 25.099 9.825 1.00 23.30 ? 42 PRO A CB 1 ATOM 271 C CG . PRO A 1 42 ? -29.462 25.503 8.909 1.00 24.91 ? 42 PRO A CG 1 ATOM 272 C CD . PRO A 1 42 ? -30.717 24.753 9.205 1.00 23.13 ? 42 PRO A CD 1 ATOM 273 N N . TRP A 1 43 ? -28.410 25.083 13.281 1.00 23.82 ? 43 TRP A N 1 ATOM 274 C CA . TRP A 1 43 ? -28.225 25.951 14.448 1.00 23.59 ? 43 TRP A CA 1 ATOM 275 C C . TRP A 1 43 ? -27.318 27.139 14.111 1.00 22.45 ? 43 TRP A C 1 ATOM 276 O O . TRP A 1 43 ? -27.438 28.231 14.665 1.00 22.52 ? 43 TRP A O 1 ATOM 277 C CB . TRP A 1 43 ? -27.612 25.119 15.576 1.00 24.97 ? 43 TRP A CB 1 ATOM 278 C CG . TRP A 1 43 ? -28.598 24.179 16.213 1.00 26.99 ? 43 TRP A CG 1 ATOM 279 C CD1 . TRP A 1 43 ? -29.881 23.914 15.800 1.00 28.81 ? 43 TRP A CD1 1 ATOM 280 C CD2 . TRP A 1 43 ? -28.374 23.368 17.370 1.00 29.14 ? 43 TRP A CD2 1 ATOM 281 N NE1 . TRP A 1 43 ? -30.467 23.002 16.642 1.00 29.59 ? 43 TRP A NE1 1 ATOM 282 C CE2 . TRP A 1 43 ? -29.565 22.649 17.613 1.00 29.35 ? 43 TRP A CE2 1 ATOM 283 C CE3 . TRP A 1 43 ? -27.286 23.199 18.241 1.00 28.27 ? 43 TRP A CE3 1 ATOM 284 C CZ2 . TRP A 1 43 ? -29.695 21.753 18.676 1.00 28.66 ? 43 TRP A CZ2 1 ATOM 285 C CZ3 . TRP A 1 43 ? -27.406 22.299 19.293 1.00 29.08 ? 43 TRP A CZ3 1 ATOM 286 C CH2 . TRP A 1 43 ? -28.613 21.595 19.509 1.00 29.56 ? 43 TRP A CH2 1 ATOM 287 N N . CYS A 1 44 ? -26.410 26.903 13.184 1.00 21.57 ? 44 CYS A N 1 ATOM 288 C CA . CYS A 1 44 ? -25.468 27.916 12.764 1.00 21.24 ? 44 CYS A CA 1 ATOM 289 C C . CYS A 1 44 ? -25.602 28.132 11.259 1.00 20.57 ? 44 CYS A C 1 ATOM 290 O O . CYS A 1 44 ? -25.411 27.200 10.461 1.00 19.52 ? 44 CYS A O 1 ATOM 291 C CB . CYS A 1 44 ? -24.054 27.487 13.121 1.00 20.20 ? 44 CYS A CB 1 ATOM 292 S SG . CYS A 1 44 ? -22.745 28.617 12.562 1.00 24.56 ? 44 CYS A SG 1 ATOM 293 N N . TYR A 1 45 ? -25.890 29.366 10.876 1.00 20.96 ? 45 TYR A N 1 ATOM 294 C CA . TYR A 1 45 ? -26.178 29.673 9.479 1.00 21.78 ? 45 TYR A CA 1 ATOM 295 C C . TYR A 1 45 ? -25.550 30.986 9.079 1.00 21.48 ? 45 TYR A C 1 ATOM 296 O O . TYR A 1 45 ? -25.215 31.805 9.938 1.00 20.99 ? 45 TYR A O 1 ATOM 297 C CB . TYR A 1 45 ? -27.690 29.711 9.273 1.00 22.45 ? 45 TYR A CB 1 ATOM 298 C CG . TYR A 1 45 ? -28.422 30.687 10.164 1.00 24.06 ? 45 TYR A CG 1 ATOM 299 C CD1 . TYR A 1 45 ? -28.795 31.949 9.689 1.00 24.29 ? 45 TYR A CD1 1 ATOM 300 C CD2 . TYR A 1 45 ? -28.764 30.345 11.477 1.00 24.46 ? 45 TYR A CD2 1 ATOM 301 C CE1 . TYR A 1 45 ? -29.461 32.851 10.508 1.00 25.25 ? 45 TYR A CE1 1 ATOM 302 C CE2 . TYR A 1 45 ? -29.423 31.235 12.297 1.00 23.83 ? 45 TYR A CE2 1 ATOM 303 C CZ . TYR A 1 45 ? -29.769 32.476 11.806 1.00 25.33 ? 45 TYR A CZ 1 ATOM 304 O OH . TYR A 1 45 ? -30.419 33.352 12.640 1.00 29.62 ? 45 TYR A OH 1 ATOM 305 N N . TYR A 1 46 ? -25.349 31.170 7.782 1.00 21.73 ? 46 TYR A N 1 ATOM 306 C CA . TYR A 1 46 ? -24.598 32.297 7.292 1.00 24.06 ? 46 TYR A CA 1 ATOM 307 C C . TYR A 1 46 ? -25.325 33.610 7.534 1.00 25.98 ? 46 TYR A C 1 ATOM 308 O O . TYR A 1 46 ? -26.549 33.682 7.451 1.00 25.41 ? 46 TYR A O 1 ATOM 309 C CB . TYR A 1 46 ? -24.237 32.126 5.823 1.00 22.96 ? 46 TYR A CB 1 ATOM 310 C CG . TYR A 1 46 ? -23.185 31.086 5.585 1.00 23.88 ? 46 TYR A CG 1 ATOM 311 C CD1 . TYR A 1 46 ? -21.832 31.344 5.882 1.00 21.63 ? 46 TYR A CD1 1 ATOM 312 C CD2 . TYR A 1 46 ? -23.517 29.852 5.033 1.00 21.40 ? 46 TYR A CD2 1 ATOM 313 C CE1 . TYR A 1 46 ? -20.843 30.369 5.648 1.00 22.78 ? 46 TYR A CE1 1 ATOM 314 C CE2 . TYR A 1 46 ? -22.527 28.872 4.819 1.00 21.80 ? 46 TYR A CE2 1 ATOM 315 C CZ . TYR A 1 46 ? -21.208 29.149 5.123 1.00 23.82 ? 46 TYR A CZ 1 ATOM 316 O OH . TYR A 1 46 ? -20.267 28.160 4.905 1.00 24.34 ? 46 TYR A OH 1 ATOM 317 N N . SER A 1 47 ? -24.561 34.639 7.887 1.00 29.31 ? 47 SER A N 1 ATOM 318 C CA . SER A 1 47 ? -25.122 35.977 8.077 1.00 33.46 ? 47 SER A CA 1 ATOM 319 C C . SER A 1 47 ? -25.377 36.649 6.736 1.00 36.59 ? 47 SER A C 1 ATOM 320 O O . SER A 1 47 ? -24.857 36.206 5.702 1.00 36.54 ? 47 SER A O 1 ATOM 321 C CB . SER A 1 47 ? -24.189 36.844 8.896 1.00 32.86 ? 47 SER A CB 1 ATOM 322 O OG . SER A 1 47 ? -22.957 36.967 8.218 1.00 33.33 ? 47 SER A OG 1 ATOM 323 N N . LYS A 1 48 ? -26.150 37.735 6.782 1.00 40.55 ? 48 LYS A N 1 ATOM 324 C CA . LYS A 1 48 ? -26.656 38.451 5.588 1.00 44.59 ? 48 LYS A CA 1 ATOM 325 C C . LYS A 1 48 ? -25.616 39.107 4.683 1.00 45.41 ? 48 LYS A C 1 ATOM 326 O O . LYS A 1 48 ? -25.949 39.525 3.570 1.00 46.46 ? 48 LYS A O 1 ATOM 327 C CB . LYS A 1 48 ? -27.704 39.505 5.983 1.00 44.38 ? 48 LYS A CB 1 ATOM 328 C CG . LYS A 1 48 ? -29.145 38.998 5.984 1.00 46.85 ? 48 LYS A CG 1 ATOM 329 C CD . LYS A 1 48 ? -30.097 40.064 6.530 1.00 47.66 ? 48 LYS A CD 1 ATOM 330 C CE . LYS A 1 48 ? -30.669 41.000 5.436 1.00 52.43 ? 48 LYS A CE 1 ATOM 331 N NZ . LYS A 1 48 ? -31.959 40.469 4.878 1.00 53.93 ? 48 LYS A NZ 1 ATOM 332 N N . ASN A 1 49 ? -24.378 39.205 5.145 1.00 46.77 ? 49 ASN A N 1 ATOM 333 C CA . ASN A 1 49 ? -23.343 39.885 4.401 1.00 48.57 ? 49 ASN A CA 1 ATOM 334 C C . ASN A 1 49 ? -22.076 39.260 4.919 1.00 48.94 ? 49 ASN A C 1 ATOM 335 O O . ASN A 1 49 ? -21.692 39.457 6.080 1.00 50.20 ? 49 ASN A O 1 ATOM 336 C CB . ASN A 1 49 ? -23.373 41.402 4.704 1.00 49.45 ? 49 ASN A CB 1 ATOM 337 C CG . ASN A 1 49 ? -23.155 42.289 3.456 1.00 51.49 ? 49 ASN A CG 1 ATOM 338 O OD1 . ASN A 1 49 ? -22.208 42.099 2.675 1.00 54.20 ? 49 ASN A OD1 1 ATOM 339 N ND2 . ASN A 1 49 ? -24.018 43.295 3.301 1.00 53.94 ? 49 ASN A ND2 1 ATOM 340 N N . HIS A 1 50 ? -21.448 38.466 4.070 1.00 48.99 ? 50 HIS A N 1 ATOM 341 C CA . HIS A 1 50 ? -20.381 37.572 4.493 1.00 48.64 ? 50 HIS A CA 1 ATOM 342 C C . HIS A 1 50 ? -19.344 37.524 3.369 1.00 47.05 ? 50 HIS A C 1 ATOM 343 O O . HIS A 1 50 ? -18.127 37.515 3.617 1.00 47.87 ? 50 HIS A O 1 ATOM 344 C CB . HIS A 1 50 ? -20.977 36.151 4.750 1.00 49.83 ? 50 HIS A CB 1 ATOM 345 C CG . HIS A 1 50 ? -19.977 35.113 5.208 1.00 52.36 ? 50 HIS A CG 1 ATOM 346 N ND1 . HIS A 1 50 ? -19.831 34.746 6.532 1.00 54.54 ? 50 HIS A ND1 1 ATOM 347 C CD2 . HIS A 1 50 ? -19.095 34.352 4.511 1.00 53.41 ? 50 HIS A CD2 1 ATOM 348 C CE1 . HIS A 1 50 ? -18.889 33.822 6.633 1.00 54.64 ? 50 HIS A CE1 1 ATOM 349 N NE2 . HIS A 1 50 ? -18.425 33.566 5.421 1.00 53.77 ? 50 HIS A NE2 1 ATOM 350 N N . SER A 1 51 ? -19.844 37.529 2.130 1.00 43.70 ? 51 SER A N 1 ATOM 351 C CA . SER A 1 51 ? -19.143 36.870 1.032 1.00 40.36 ? 51 SER A CA 1 ATOM 352 C C . SER A 1 51 ? -18.377 37.785 0.056 1.00 37.53 ? 51 SER A C 1 ATOM 353 O O . SER A 1 51 ? -17.322 38.321 0.395 1.00 38.90 ? 51 SER A O 1 ATOM 354 C CB . SER A 1 51 ? -20.116 35.942 0.283 1.00 40.74 ? 51 SER A CB 1 ATOM 355 O OG . SER A 1 51 ? -21.158 36.667 -0.343 1.00 39.63 ? 51 SER A OG 1 ATOM 356 N N . TYR A 1 52 ? -18.899 37.937 -1.152 1.00 32.70 ? 52 TYR A N 1 ATOM 357 C CA . TYR A 1 52 ? -18.220 38.686 -2.193 1.00 28.23 ? 52 TYR A CA 1 ATOM 358 C C . TYR A 1 52 ? -19.013 39.930 -2.501 1.00 26.89 ? 52 TYR A C 1 ATOM 359 O O . TYR A 1 52 ? -20.235 39.972 -2.302 1.00 26.24 ? 52 TYR A O 1 ATOM 360 C CB . TYR A 1 52 ? -18.045 37.807 -3.450 1.00 26.68 ? 52 TYR A CB 1 ATOM 361 C CG . TYR A 1 52 ? -16.907 36.821 -3.305 1.00 24.26 ? 52 TYR A CG 1 ATOM 362 C CD1 . TYR A 1 52 ? -17.070 35.622 -2.593 1.00 19.91 ? 52 TYR A CD1 1 ATOM 363 C CD2 . TYR A 1 52 ? -15.663 37.089 -3.864 1.00 22.07 ? 52 TYR A CD2 1 ATOM 364 C CE1 . TYR A 1 52 ? -16.018 34.696 -2.455 1.00 23.33 ? 52 TYR A CE1 1 ATOM 365 C CE2 . TYR A 1 52 ? -14.583 36.168 -3.707 1.00 23.78 ? 52 TYR A CE2 1 ATOM 366 C CZ . TYR A 1 52 ? -14.776 35.000 -3.005 1.00 23.57 ? 52 TYR A CZ 1 ATOM 367 O OH . TYR A 1 52 ? -13.723 34.126 -2.878 1.00 25.46 ? 52 TYR A OH 1 ATOM 368 N N . HIS A 1 53 ? -18.327 40.957 -2.974 1.00 25.73 ? 53 HIS A N 1 ATOM 369 C CA . HIS A 1 53 ? -19.036 42.089 -3.515 1.00 26.12 ? 53 HIS A CA 1 ATOM 370 C C . HIS A 1 53 ? -18.497 42.375 -4.888 1.00 24.46 ? 53 HIS A C 1 ATOM 371 O O . HIS A 1 53 ? -17.347 42.072 -5.205 1.00 24.18 ? 53 HIS A O 1 ATOM 372 C CB . HIS A 1 53 ? -18.973 43.317 -2.587 1.00 27.10 ? 53 HIS A CB 1 ATOM 373 C CG . HIS A 1 53 ? -17.595 43.856 -2.406 1.00 29.71 ? 53 HIS A CG 1 ATOM 374 N ND1 . HIS A 1 53 ? -17.107 44.913 -3.144 1.00 34.73 ? 53 HIS A ND1 1 ATOM 375 C CD2 . HIS A 1 53 ? -16.585 43.462 -1.599 1.00 33.16 ? 53 HIS A CD2 1 ATOM 376 C CE1 . HIS A 1 53 ? -15.854 45.148 -2.798 1.00 33.28 ? 53 HIS A CE1 1 ATOM 377 N NE2 . HIS A 1 53 ? -15.512 44.278 -1.867 1.00 33.33 ? 53 HIS A NE2 1 ATOM 378 N N . VAL A 1 54 ? -19.354 42.944 -5.725 1.00 23.84 ? 54 VAL A N 1 ATOM 379 C CA . VAL A 1 54 ? -18.925 43.377 -7.042 1.00 23.24 ? 54 VAL A CA 1 ATOM 380 C C . VAL A 1 54 ? -18.013 44.604 -6.863 1.00 23.92 ? 54 VAL A C 1 ATOM 381 O O . VAL A 1 54 ? -18.358 45.555 -6.149 1.00 24.54 ? 54 VAL A O 1 ATOM 382 C CB . VAL A 1 54 ? -20.131 43.716 -7.954 1.00 23.14 ? 54 VAL A CB 1 ATOM 383 C CG1 . VAL A 1 54 ? -19.651 44.238 -9.296 1.00 23.25 ? 54 VAL A CG1 1 ATOM 384 C CG2 . VAL A 1 54 ? -20.983 42.455 -8.163 1.00 22.49 ? 54 VAL A CG2 1 ATOM 385 N N . GLU A 1 55 ? -16.868 44.566 -7.526 1.00 23.95 ? 55 GLU A N 1 ATOM 386 C CA . GLU A 1 55 ? -15.951 45.674 -7.536 1.00 26.47 ? 55 GLU A CA 1 ATOM 387 C C . GLU A 1 55 ? -16.077 46.427 -8.871 1.00 26.20 ? 55 GLU A C 1 ATOM 388 O O . GLU A 1 55 ? -15.783 45.887 -9.958 1.00 26.71 ? 55 GLU A O 1 ATOM 389 C CB . GLU A 1 55 ? -14.529 45.169 -7.292 1.00 27.39 ? 55 GLU A CB 1 ATOM 390 C CG . GLU A 1 55 ? -13.441 46.257 -7.269 1.00 34.61 ? 55 GLU A CG 1 ATOM 391 C CD . GLU A 1 55 ? -13.293 46.993 -5.913 1.00 42.76 ? 55 GLU A CD 1 ATOM 392 O OE1 . GLU A 1 55 ? -14.119 46.786 -4.981 1.00 45.39 ? 55 GLU A OE1 1 ATOM 393 O OE2 . GLU A 1 55 ? -12.320 47.783 -5.779 1.00 46.06 ? 55 GLU A OE2 1 ATOM 394 N N . GLY A 1 56 ? -16.561 47.658 -8.787 1.00 25.59 ? 56 GLY A N 1 ATOM 395 C CA . GLY A 1 56 ? -16.633 48.506 -9.962 1.00 25.65 ? 56 GLY A CA 1 ATOM 396 C C . GLY A 1 56 ? -17.787 48.118 -10.866 1.00 24.93 ? 56 GLY A C 1 ATOM 397 O O . GLY A 1 56 ? -18.802 47.581 -10.400 1.00 25.60 ? 56 GLY A O 1 ATOM 398 N N . ASN A 1 57 ? -17.648 48.391 -12.149 1.00 23.52 ? 57 ASN A N 1 ATOM 399 C CA . ASN A 1 57 ? -18.763 48.181 -13.102 1.00 22.14 ? 57 ASN A CA 1 ATOM 400 C C . ASN A 1 57 ? -18.697 46.820 -13.759 1.00 20.90 ? 57 ASN A C 1 ATOM 401 O O . ASN A 1 57 ? -17.609 46.266 -13.978 1.00 20.91 ? 57 ASN A O 1 ATOM 402 C CB . ASN A 1 57 ? -18.749 49.246 -14.208 1.00 22.35 ? 57 ASN A CB 1 ATOM 403 C CG . ASN A 1 57 ? -19.010 50.652 -13.685 1.00 23.28 ? 57 ASN A CG 1 ATOM 404 O OD1 . ASN A 1 57 ? -19.632 50.834 -12.642 1.00 22.73 ? 57 ASN A OD1 1 ATOM 405 N ND2 . ASN A 1 57 ? -18.526 51.652 -14.416 1.00 24.31 ? 57 ASN A ND2 1 ATOM 406 N N . LEU A 1 58 ? -19.861 46.282 -14.089 1.00 19.52 ? 58 LEU A N 1 ATOM 407 C CA . LEU A 1 58 ? -19.966 45.195 -15.046 1.00 19.76 ? 58 LEU A CA 1 ATOM 408 C C . LEU A 1 58 ? -19.568 45.681 -16.418 1.00 19.29 ? 58 LEU A C 1 ATOM 409 O O . LEU A 1 58 ? -19.831 46.834 -16.784 1.00 19.79 ? 58 LEU A O 1 ATOM 410 C CB . LEU A 1 58 ? -21.403 44.625 -15.121 1.00 18.72 ? 58 LEU A CB 1 ATOM 411 C CG . LEU A 1 58 ? -21.832 43.553 -14.113 1.00 20.73 ? 58 LEU A CG 1 ATOM 412 C CD1 . LEU A 1 58 ? -21.456 43.965 -12.726 1.00 20.77 ? 58 LEU A CD1 1 ATOM 413 C CD2 . LEU A 1 58 ? -23.375 43.281 -14.154 1.00 19.80 ? 58 LEU A CD2 1 ATOM 414 N N . VAL A 1 59 ? -18.908 44.805 -17.161 1.00 20.01 ? 59 VAL A N 1 ATOM 415 C CA . VAL A 1 59 ? -18.469 45.105 -18.525 1.00 21.20 ? 59 VAL A CA 1 ATOM 416 C C . VAL A 1 59 ? -19.256 44.271 -19.534 1.00 20.51 ? 59 VAL A C 1 ATOM 417 O O . VAL A 1 59 ? -19.223 43.067 -19.465 1.00 19.64 ? 59 VAL A O 1 ATOM 418 C CB . VAL A 1 59 ? -16.980 44.736 -18.708 1.00 21.55 ? 59 VAL A CB 1 ATOM 419 C CG1 . VAL A 1 59 ? -16.509 45.115 -20.100 1.00 23.57 ? 59 VAL A CG1 1 ATOM 420 C CG2 . VAL A 1 59 ? -16.154 45.400 -17.628 1.00 23.27 ? 59 VAL A CG2 1 ATOM 421 N N . ASN A 1 60 ? -19.918 44.914 -20.494 1.00 21.11 ? 60 ASN A N 1 ATOM 422 C CA . ASN A 1 60 ? -20.491 44.193 -21.636 1.00 21.02 ? 60 ASN A CA 1 ATOM 423 C C . ASN A 1 60 ? -19.462 43.518 -22.499 1.00 22.36 ? 60 ASN A C 1 ATOM 424 O O . ASN A 1 60 ? -18.410 44.104 -22.783 1.00 21.78 ? 60 ASN A O 1 ATOM 425 C CB . ASN A 1 60 ? -21.227 45.152 -22.533 1.00 22.65 ? 60 ASN A CB 1 ATOM 426 C CG . ASN A 1 60 ? -22.492 45.617 -21.910 1.00 22.31 ? 60 ASN A CG 1 ATOM 427 O OD1 . ASN A 1 60 ? -23.490 44.904 -21.902 1.00 27.77 ? 60 ASN A OD1 1 ATOM 428 N ND2 . ASN A 1 60 ? -22.453 46.783 -21.322 1.00 22.99 ? 60 ASN A ND2 1 ATOM 429 N N . THR A 1 61 ? -19.773 42.297 -22.924 1.00 20.89 ? 61 THR A N 1 ATOM 430 C CA . THR A 1 61 ? -18.931 41.545 -23.832 1.00 21.60 ? 61 THR A CA 1 ATOM 431 C C . THR A 1 61 ? -19.880 41.177 -24.970 1.00 21.69 ? 61 THR A C 1 ATOM 432 O O . THR A 1 61 ? -21.104 41.353 -24.842 1.00 21.71 ? 61 THR A O 1 ATOM 433 C CB . THR A 1 61 ? -18.425 40.272 -23.185 1.00 21.67 ? 61 THR A CB 1 ATOM 434 O OG1 . THR A 1 61 ? -19.550 39.457 -22.817 1.00 22.43 ? 61 THR A OG1 1 ATOM 435 C CG2 . THR A 1 61 ? -17.573 40.554 -21.932 1.00 21.65 ? 61 THR A CG2 1 ATOM 436 N N . ASN A 1 62 ? -19.334 40.685 -26.072 1.00 22.18 ? 62 ASN A N 1 ATOM 437 C CA . ASN A 1 62 ? -20.166 40.192 -27.184 1.00 23.52 ? 62 ASN A CA 1 ATOM 438 C C . ASN A 1 62 ? -21.211 39.148 -26.750 1.00 22.41 ? 62 ASN A C 1 ATOM 439 O O . ASN A 1 62 ? -22.339 39.151 -27.254 1.00 23.10 ? 62 ASN A O 1 ATOM 440 C CB . ASN A 1 62 ? -19.272 39.599 -28.292 1.00 24.44 ? 62 ASN A CB 1 ATOM 441 C CG . ASN A 1 62 ? -18.512 40.675 -29.084 1.00 29.26 ? 62 ASN A CG 1 ATOM 442 O OD1 . ASN A 1 62 ? -17.391 40.439 -29.578 1.00 34.78 ? 62 ASN A OD1 1 ATOM 443 N ND2 . ASN A 1 62 ? -19.120 41.839 -29.229 1.00 29.40 ? 62 ASN A ND2 1 ATOM 444 N N . ALA A 1 63 ? -20.813 38.267 -25.828 1.00 21.50 ? 63 ALA A N 1 ATOM 445 C CA . ALA A 1 63 ? -21.622 37.126 -25.357 1.00 20.93 ? 63 ALA A CA 1 ATOM 446 C C . ALA A 1 63 ? -22.569 37.468 -24.204 1.00 20.74 ? 63 ALA A C 1 ATOM 447 O O . ALA A 1 63 ? -23.559 36.771 -23.993 1.00 20.88 ? 63 ALA A O 1 ATOM 448 C CB . ALA A 1 63 ? -20.689 36.004 -24.932 1.00 22.02 ? 63 ALA A CB 1 ATOM 449 N N . GLY A 1 64 ? -22.241 38.507 -23.433 1.00 19.49 ? 64 GLY A N 1 ATOM 450 C CA . GLY A 1 64 ? -22.985 38.880 -22.234 1.00 18.91 ? 64 GLY A CA 1 ATOM 451 C C . GLY A 1 64 ? -22.257 39.953 -21.427 1.00 18.72 ? 64 GLY A C 1 ATOM 452 O O . GLY A 1 64 ? -22.192 41.115 -21.832 1.00 18.41 ? 64 GLY A O 1 ATOM 453 N N . PHE A 1 65 ? -21.699 39.571 -20.292 1.00 18.10 ? 65 PHE A N 1 ATOM 454 C CA . PHE A 1 65 ? -20.965 40.516 -19.442 1.00 18.11 ? 65 PHE A CA 1 ATOM 455 C C . PHE A 1 65 ? -20.000 39.799 -18.532 1.00 19.21 ? 65 PHE A C 1 ATOM 456 O O . PHE A 1 65 ? -20.109 38.570 -18.329 1.00 17.82 ? 65 PHE A O 1 ATOM 457 C CB . PHE A 1 65 ? -21.885 41.384 -18.590 1.00 18.90 ? 65 PHE A CB 1 ATOM 458 C CG . PHE A 1 65 ? -22.766 40.594 -17.634 1.00 20.97 ? 65 PHE A CG 1 ATOM 459 C CD1 . PHE A 1 65 ? -22.337 40.326 -16.328 1.00 20.48 ? 65 PHE A CD1 1 ATOM 460 C CD2 . PHE A 1 65 ? -24.040 40.147 -18.041 1.00 23.67 ? 65 PHE A CD2 1 ATOM 461 C CE1 . PHE A 1 65 ? -23.114 39.597 -15.449 1.00 19.07 ? 65 PHE A CE1 1 ATOM 462 C CE2 . PHE A 1 65 ? -24.858 39.445 -17.172 1.00 19.62 ? 65 PHE A CE2 1 ATOM 463 C CZ . PHE A 1 65 ? -24.413 39.157 -15.876 1.00 20.19 ? 65 PHE A CZ 1 ATOM 464 N N . THR A 1 66 ? -19.039 40.573 -18.006 1.00 18.09 ? 66 THR A N 1 ATOM 465 C CA . THR A 1 66 ? -18.220 40.111 -16.902 1.00 19.04 ? 66 THR A CA 1 ATOM 466 C C . THR A 1 66 ? -18.289 41.059 -15.708 1.00 19.18 ? 66 THR A C 1 ATOM 467 O O . THR A 1 66 ? -18.567 42.256 -15.852 1.00 21.26 ? 66 THR A O 1 ATOM 468 C CB . THR A 1 66 ? -16.748 39.945 -17.344 1.00 19.02 ? 66 THR A CB 1 ATOM 469 O OG1 . THR A 1 66 ? -16.278 41.171 -17.910 1.00 21.49 ? 66 THR A OG1 1 ATOM 470 C CG2 . THR A 1 66 ? -16.608 38.850 -18.400 1.00 18.88 ? 66 THR A CG2 1 ATOM 471 N N . ALA A 1 67 ? -18.026 40.514 -14.523 1.00 19.74 ? 67 ALA A N 1 ATOM 472 C CA . ALA A 1 67 ? -17.911 41.278 -13.313 1.00 20.36 ? 67 ALA A CA 1 ATOM 473 C C . ALA A 1 67 ? -16.705 40.788 -12.532 1.00 21.19 ? 67 ALA A C 1 ATOM 474 O O . ALA A 1 67 ? -16.335 39.604 -12.588 1.00 21.30 ? 67 ALA A O 1 ATOM 475 C CB . ALA A 1 67 ? -19.139 41.093 -12.483 1.00 19.35 ? 67 ALA A CB 1 ATOM 476 N N . ARG A 1 68 ? -16.080 41.715 -11.827 1.00 21.37 ? 68 ARG A N 1 ATOM 477 C CA A ARG A 1 68 ? -15.028 41.365 -10.874 0.50 22.48 ? 68 ARG A CA 1 ATOM 478 C CA B ARG A 1 68 ? -15.019 41.378 -10.866 0.50 22.84 ? 68 ARG A CA 1 ATOM 479 C C . ARG A 1 68 ? -15.654 41.336 -9.494 1.00 22.92 ? 68 ARG A C 1 ATOM 480 O O . ARG A 1 68 ? -16.319 42.299 -9.096 1.00 23.46 ? 68 ARG A O 1 ATOM 481 C CB A ARG A 1 68 ? -13.872 42.370 -10.955 0.50 22.55 ? 68 ARG A CB 1 ATOM 482 C CB B ARG A 1 68 ? -13.875 42.409 -10.905 0.50 22.53 ? 68 ARG A CB 1 ATOM 483 C CG A ARG A 1 68 ? -13.039 42.230 -12.214 0.50 23.40 ? 68 ARG A CG 1 ATOM 484 C CG B ARG A 1 68 ? -12.979 42.394 -9.662 0.50 22.99 ? 68 ARG A CG 1 ATOM 485 C CD A ARG A 1 68 ? -12.223 43.496 -12.504 0.50 27.74 ? 68 ARG A CD 1 ATOM 486 C CD B ARG A 1 68 ? -11.927 43.494 -9.698 0.50 24.95 ? 68 ARG A CD 1 ATOM 487 N NE A ARG A 1 68 ? -10.880 43.181 -12.982 0.50 29.78 ? 68 ARG A NE 1 ATOM 488 N NE B ARG A 1 68 ? -10.931 43.336 -8.639 0.50 27.29 ? 68 ARG A NE 1 ATOM 489 C CZ A ARG A 1 68 ? -10.166 43.945 -13.809 0.50 32.51 ? 68 ARG A CZ 1 ATOM 490 C CZ B ARG A 1 68 ? -10.049 44.276 -8.295 0.50 30.14 ? 68 ARG A CZ 1 ATOM 491 N NH1 A ARG A 1 68 ? -10.661 45.086 -14.281 0.50 32.96 ? 68 ARG A NH1 1 ATOM 492 N NH1 B ARG A 1 68 ? -10.042 45.446 -8.916 0.50 30.24 ? 68 ARG A NH1 1 ATOM 493 N NH2 A ARG A 1 68 ? -8.944 43.560 -14.172 0.50 33.22 ? 68 ARG A NH2 1 ATOM 494 N NH2 B ARG A 1 68 ? -9.166 44.053 -7.326 0.50 30.70 ? 68 ARG A NH2 1 ATOM 495 N N . LEU A 1 69 ? -15.486 40.204 -8.794 1.00 22.60 ? 69 LEU A N 1 ATOM 496 C CA . LEU A 1 69 ? -15.956 40.043 -7.448 1.00 23.65 ? 69 LEU A CA 1 ATOM 497 C C . LEU A 1 69 ? -14.757 40.072 -6.495 1.00 25.58 ? 69 LEU A C 1 ATOM 498 O O . LEU A 1 69 ? -13.697 39.493 -6.776 1.00 24.90 ? 69 LEU A O 1 ATOM 499 C CB . LEU A 1 69 ? -16.721 38.736 -7.296 1.00 23.76 ? 69 LEU A CB 1 ATOM 500 C CG . LEU A 1 69 ? -17.789 38.413 -8.332 1.00 24.01 ? 69 LEU A CG 1 ATOM 501 C CD1 . LEU A 1 69 ? -18.617 37.234 -7.796 1.00 23.13 ? 69 LEU A CD1 1 ATOM 502 C CD2 . LEU A 1 69 ? -18.636 39.617 -8.576 1.00 23.62 ? 69 LEU A CD2 1 ATOM 503 N N . LYS A 1 70 ? -14.910 40.779 -5.395 1.00 27.17 ? 70 LYS A N 1 ATOM 504 C CA . LYS A 1 70 ? -13.825 40.896 -4.453 1.00 31.12 ? 70 LYS A CA 1 ATOM 505 C C . LYS A 1 70 ? -14.289 40.305 -3.143 1.00 31.16 ? 70 LYS A C 1 ATOM 506 O O . LYS A 1 70 ? -15.398 40.557 -2.703 1.00 30.35 ? 70 LYS A O 1 ATOM 507 C CB . LYS A 1 70 ? -13.394 42.370 -4.329 1.00 30.69 ? 70 LYS A CB 1 ATOM 508 C CG . LYS A 1 70 ? -12.055 42.616 -3.628 1.00 34.90 ? 70 LYS A CG 1 ATOM 509 C CD . LYS A 1 70 ? -11.689 44.120 -3.683 1.00 34.75 ? 70 LYS A CD 1 ATOM 510 C CE . LYS A 1 70 ? -10.572 44.464 -2.665 1.00 42.52 ? 70 LYS A CE 1 ATOM 511 N NZ . LYS A 1 70 ? -9.956 45.791 -2.972 1.00 43.30 ? 70 LYS A NZ 1 ATOM 512 N N . ASN A 1 71 ? -13.436 39.486 -2.537 1.00 34.17 ? 71 ASN A N 1 ATOM 513 C CA . ASN A 1 71 ? -13.749 38.858 -1.268 1.00 37.48 ? 71 ASN A CA 1 ATOM 514 C C . ASN A 1 71 ? -13.823 39.903 -0.162 1.00 39.86 ? 71 ASN A C 1 ATOM 515 O O . ASN A 1 71 ? -12.872 40.652 0.062 1.00 40.02 ? 71 ASN A O 1 ATOM 516 C CB . ASN A 1 71 ? -12.704 37.779 -0.933 1.00 37.70 ? 71 ASN A CB 1 ATOM 517 C CG . ASN A 1 71 ? -13.039 36.999 0.322 1.00 38.57 ? 71 ASN A CG 1 ATOM 518 O OD1 . ASN A 1 71 ? -14.158 36.508 0.498 1.00 38.83 ? 71 ASN A OD1 1 ATOM 519 N ND2 . ASN A 1 71 ? -12.054 36.885 1.219 1.00 41.61 ? 71 ASN A ND2 1 ATOM 520 N N . LEU A 1 72 ? -14.972 39.949 0.502 1.00 43.18 ? 72 LEU A N 1 ATOM 521 C CA . LEU A 1 72 ? -15.146 40.700 1.748 1.00 46.65 ? 72 LEU A CA 1 ATOM 522 C C . LEU A 1 72 ? -14.462 39.923 2.884 1.00 48.64 ? 72 LEU A C 1 ATOM 523 O O . LEU A 1 72 ? -14.695 38.720 3.040 1.00 48.79 ? 72 LEU A O 1 ATOM 524 C CB . LEU A 1 72 ? -16.642 40.892 2.061 1.00 46.86 ? 72 LEU A CB 1 ATOM 525 C CG . LEU A 1 72 ? -17.480 41.886 1.247 1.00 47.53 ? 72 LEU A CG 1 ATOM 526 C CD1 . LEU A 1 72 ? -18.968 41.600 1.395 1.00 48.38 ? 72 LEU A CD1 1 ATOM 527 C CD2 . LEU A 1 72 ? -17.172 43.351 1.643 1.00 48.18 ? 72 LEU A CD2 1 ATOM 528 N N . PRO A 1 73 ? -13.644 40.614 3.700 1.00 50.86 ? 73 PRO A N 1 ATOM 529 C CA . PRO A 1 73 ? -12.760 39.916 4.660 1.00 52.29 ? 73 PRO A CA 1 ATOM 530 C C . PRO A 1 73 ? -13.506 38.825 5.455 1.00 52.99 ? 73 PRO A C 1 ATOM 531 O O . PRO A 1 73 ? -14.620 39.049 5.934 1.00 53.03 ? 73 PRO A O 1 ATOM 532 C CB . PRO A 1 73 ? -12.248 41.051 5.572 1.00 52.62 ? 73 PRO A CB 1 ATOM 533 C CG . PRO A 1 73 ? -12.320 42.310 4.695 1.00 52.84 ? 73 PRO A CG 1 ATOM 534 C CD . PRO A 1 73 ? -13.545 42.088 3.801 1.00 51.41 ? 73 PRO A CD 1 ATOM 535 N N . SER A 1 74 ? -12.907 37.645 5.556 1.00 53.83 ? 74 SER A N 1 ATOM 536 C CA . SER A 1 74 ? -13.649 36.475 6.013 1.00 54.66 ? 74 SER A CA 1 ATOM 537 C C . SER A 1 74 ? -12.719 35.420 6.614 1.00 54.83 ? 74 SER A C 1 ATOM 538 O O . SER A 1 74 ? -11.569 35.293 6.188 1.00 54.88 ? 74 SER A O 1 ATOM 539 C CB . SER A 1 74 ? -14.427 35.889 4.830 1.00 54.85 ? 74 SER A CB 1 ATOM 540 O OG . SER A 1 74 ? -15.455 35.034 5.277 1.00 56.60 ? 74 SER A OG 1 ATOM 541 N N . SER A 1 75 ? -13.214 34.664 7.597 1.00 55.07 ? 75 SER A N 1 ATOM 542 C CA . SER A 1 75 ? -12.400 33.627 8.266 1.00 55.22 ? 75 SER A CA 1 ATOM 543 C C . SER A 1 75 ? -12.101 32.439 7.322 1.00 54.68 ? 75 SER A C 1 ATOM 544 O O . SER A 1 75 ? -12.970 32.039 6.553 1.00 55.05 ? 75 SER A O 1 ATOM 545 C CB . SER A 1 75 ? -13.095 33.153 9.549 1.00 55.46 ? 75 SER A CB 1 ATOM 546 O OG . SER A 1 75 ? -14.335 32.537 9.237 1.00 56.82 ? 75 SER A OG 1 ATOM 547 N N . PRO A 1 76 ? -10.872 31.875 7.371 1.00 54.03 ? 76 PRO A N 1 ATOM 548 C CA . PRO A 1 76 ? -10.510 30.869 6.375 1.00 53.31 ? 76 PRO A CA 1 ATOM 549 C C . PRO A 1 76 ? -10.799 29.426 6.831 1.00 52.27 ? 76 PRO A C 1 ATOM 550 O O . PRO A 1 76 ? -9.876 28.695 7.221 1.00 53.02 ? 76 PRO A O 1 ATOM 551 C CB . PRO A 1 76 ? -9.003 31.099 6.194 1.00 53.44 ? 76 PRO A CB 1 ATOM 552 C CG . PRO A 1 76 ? -8.534 31.687 7.515 1.00 53.98 ? 76 PRO A CG 1 ATOM 553 C CD . PRO A 1 76 ? -9.760 32.114 8.311 1.00 54.33 ? 76 PRO A CD 1 ATOM 554 N N . VAL A 1 77 ? -12.065 29.016 6.747 1.00 50.37 ? 77 VAL A N 1 ATOM 555 C CA . VAL A 1 77 ? -12.512 27.728 7.294 1.00 48.31 ? 77 VAL A CA 1 ATOM 556 C C . VAL A 1 77 ? -11.934 26.495 6.592 1.00 47.09 ? 77 VAL A C 1 ATOM 557 O O . VAL A 1 77 ? -11.345 25.618 7.239 1.00 47.13 ? 77 VAL A O 1 ATOM 558 C CB . VAL A 1 77 ? -14.047 27.644 7.323 1.00 48.42 ? 77 VAL A CB 1 ATOM 559 C CG1 . VAL A 1 77 ? -14.484 26.338 7.943 1.00 48.47 ? 77 VAL A CG1 1 ATOM 560 C CG2 . VAL A 1 77 ? -14.619 28.823 8.093 1.00 48.40 ? 77 VAL A CG2 1 ATOM 561 N N . PHE A 1 78 ? -12.110 26.410 5.278 1.00 44.90 ? 78 PHE A N 1 ATOM 562 C CA . PHE A 1 78 ? -11.616 25.251 4.535 1.00 43.24 ? 78 PHE A CA 1 ATOM 563 C C . PHE A 1 78 ? -10.465 25.674 3.676 1.00 43.63 ? 78 PHE A C 1 ATOM 564 O O . PHE A 1 78 ? -10.304 25.235 2.532 1.00 43.40 ? 78 PHE A O 1 ATOM 565 C CB . PHE A 1 78 ? -12.742 24.579 3.769 1.00 41.70 ? 78 PHE A CB 1 ATOM 566 C CG . PHE A 1 78 ? -13.857 24.176 4.653 1.00 39.61 ? 78 PHE A CG 1 ATOM 567 C CD1 . PHE A 1 78 ? -15.090 24.778 4.552 1.00 37.02 ? 78 PHE A CD1 1 ATOM 568 C CD2 . PHE A 1 78 ? -13.644 23.247 5.661 1.00 37.81 ? 78 PHE A CD2 1 ATOM 569 C CE1 . PHE A 1 78 ? -16.120 24.424 5.404 1.00 39.27 ? 78 PHE A CE1 1 ATOM 570 C CE2 . PHE A 1 78 ? -14.668 22.890 6.518 1.00 36.86 ? 78 PHE A CE2 1 ATOM 571 C CZ . PHE A 1 78 ? -15.907 23.479 6.388 1.00 38.60 ? 78 PHE A CZ 1 ATOM 572 N N . GLY A 1 79 ? -9.671 26.551 4.289 1.00 43.94 ? 79 GLY A N 1 ATOM 573 C CA . GLY A 1 79 ? -8.415 27.027 3.761 1.00 44.09 ? 79 GLY A CA 1 ATOM 574 C C . GLY A 1 79 ? -8.488 28.123 2.722 1.00 44.24 ? 79 GLY A C 1 ATOM 575 O O . GLY A 1 79 ? -9.372 29.004 2.765 1.00 43.87 ? 79 GLY A O 1 ATOM 576 N N . SER A 1 80 ? -7.530 28.007 1.793 1.00 44.40 ? 80 SER A N 1 ATOM 577 C CA . SER A 1 80 ? -7.129 28.982 0.768 1.00 44.19 ? 80 SER A CA 1 ATOM 578 C C . SER A 1 80 ? -8.220 29.660 -0.079 1.00 43.24 ? 80 SER A C 1 ATOM 579 O O . SER A 1 80 ? -8.503 29.227 -1.199 1.00 43.26 ? 80 SER A O 1 ATOM 580 C CB . SER A 1 80 ? -6.092 28.331 -0.166 1.00 44.70 ? 80 SER A CB 1 ATOM 581 O OG . SER A 1 80 ? -4.967 27.882 0.573 1.00 46.81 ? 80 SER A OG 1 ATOM 582 N N . ASN A 1 81 ? -8.756 30.751 0.460 1.00 41.18 ? 81 ASN A N 1 ATOM 583 C CA . ASN A 1 81 ? -9.801 31.546 -0.147 1.00 40.21 ? 81 ASN A CA 1 ATOM 584 C C . ASN A 1 81 ? -9.371 32.350 -1.400 1.00 39.34 ? 81 ASN A C 1 ATOM 585 O O . ASN A 1 81 ? -8.186 32.682 -1.564 1.00 39.80 ? 81 ASN A O 1 ATOM 586 C CB . ASN A 1 81 ? -10.351 32.472 0.909 1.00 40.01 ? 81 ASN A CB 1 ATOM 587 C CG . ASN A 1 81 ? -11.702 32.948 0.579 1.00 42.63 ? 81 ASN A CG 1 ATOM 588 O OD1 . ASN A 1 81 ? -11.889 33.659 -0.402 1.00 45.66 ? 81 ASN A OD1 1 ATOM 589 N ND2 . ASN A 1 81 ? -12.683 32.559 1.388 1.00 44.62 ? 81 ASN A ND2 1 ATOM 590 N N . VAL A 1 82 ? -10.322 32.645 -2.293 1.00 36.83 ? 82 VAL A N 1 ATOM 591 C CA . VAL A 1 82 ? -9.976 33.259 -3.575 1.00 34.87 ? 82 VAL A CA 1 ATOM 592 C C . VAL A 1 82 ? -10.382 34.734 -3.527 1.00 34.65 ? 82 VAL A C 1 ATOM 593 O O . VAL A 1 82 ? -11.577 35.059 -3.451 1.00 34.39 ? 82 VAL A O 1 ATOM 594 C CB . VAL A 1 82 ? -10.545 32.436 -4.806 1.00 35.14 ? 82 VAL A CB 1 ATOM 595 C CG1 . VAL A 1 82 ? -10.507 33.219 -6.076 1.00 33.40 ? 82 VAL A CG1 1 ATOM 596 C CG2 . VAL A 1 82 ? -9.750 31.148 -4.996 1.00 33.47 ? 82 VAL A CG2 1 ATOM 597 N N . ASP A 1 83 ? -9.386 35.621 -3.528 1.00 32.88 ? 83 ASP A N 1 ATOM 598 C CA . ASP A 1 83 ? -9.625 37.046 -3.271 1.00 33.75 ? 83 ASP A CA 1 ATOM 599 C C . ASP A 1 83 ? -10.316 37.779 -4.411 1.00 32.05 ? 83 ASP A C 1 ATOM 600 O O . ASP A 1 83 ? -11.192 38.593 -4.161 1.00 33.16 ? 83 ASP A O 1 ATOM 601 C CB . ASP A 1 83 ? -8.336 37.782 -2.918 1.00 34.66 ? 83 ASP A CB 1 ATOM 602 C CG . ASP A 1 83 ? -7.771 37.337 -1.589 1.00 39.49 ? 83 ASP A CG 1 ATOM 603 O OD1 . ASP A 1 83 ? -8.577 36.951 -0.694 1.00 43.77 ? 83 ASP A OD1 1 ATOM 604 O OD2 . ASP A 1 83 ? -6.523 37.357 -1.446 1.00 43.49 ? 83 ASP A OD2 1 ATOM 605 N N . ASN A 1 84 ? -9.928 37.478 -5.645 1.00 29.99 ? 84 ASN A N 1 ATOM 606 C CA . ASN A 1 84 ? -10.530 38.093 -6.819 1.00 28.54 ? 84 ASN A CA 1 ATOM 607 C C . ASN A 1 84 ? -11.126 37.050 -7.706 1.00 26.71 ? 84 ASN A C 1 ATOM 608 O O . ASN A 1 84 ? -10.415 36.226 -8.274 1.00 25.51 ? 84 ASN A O 1 ATOM 609 C CB . ASN A 1 84 ? -9.487 38.862 -7.598 1.00 29.81 ? 84 ASN A CB 1 ATOM 610 C CG . ASN A 1 84 ? -8.927 39.998 -6.810 1.00 32.77 ? 84 ASN A CG 1 ATOM 611 O OD1 . ASN A 1 84 ? -7.856 39.872 -6.230 1.00 39.58 ? 84 ASN A OD1 1 ATOM 612 N ND2 . ASN A 1 84 ? -9.678 41.099 -6.723 1.00 37.32 ? 84 ASN A ND2 1 ATOM 613 N N . VAL A 1 85 ? -12.444 37.104 -7.800 1.00 24.20 ? 85 VAL A N 1 ATOM 614 C CA . VAL A 1 85 ? -13.237 36.147 -8.563 1.00 22.51 ? 85 VAL A CA 1 ATOM 615 C C . VAL A 1 85 ? -13.797 36.866 -9.801 1.00 22.22 ? 85 VAL A C 1 ATOM 616 O O . VAL A 1 85 ? -14.200 38.041 -9.723 1.00 22.76 ? 85 VAL A O 1 ATOM 617 C CB . VAL A 1 85 ? -14.333 35.541 -7.637 1.00 22.07 ? 85 VAL A CB 1 ATOM 618 C CG1 . VAL A 1 85 ? -15.510 34.850 -8.436 1.00 19.56 ? 85 VAL A CG1 1 ATOM 619 C CG2 . VAL A 1 85 ? -13.684 34.549 -6.670 1.00 22.24 ? 85 VAL A CG2 1 ATOM 620 N N . LEU A 1 86 ? -13.786 36.184 -10.941 1.00 20.80 ? 86 LEU A N 1 ATOM 621 C CA . LEU A 1 86 ? -14.316 36.739 -12.148 1.00 20.83 ? 86 LEU A CA 1 ATOM 622 C C . LEU A 1 86 ? -15.613 36.003 -12.412 1.00 20.19 ? 86 LEU A C 1 ATOM 623 O O . LEU A 1 86 ? -15.652 34.778 -12.371 1.00 20.03 ? 86 LEU A O 1 ATOM 624 C CB . LEU A 1 86 ? -13.357 36.542 -13.329 1.00 20.83 ? 86 LEU A CB 1 ATOM 625 C CG . LEU A 1 86 ? -13.801 37.094 -14.701 1.00 21.31 ? 86 LEU A CG 1 ATOM 626 C CD1 . LEU A 1 86 ? -13.685 38.588 -14.756 1.00 23.19 ? 86 LEU A CD1 1 ATOM 627 C CD2 . LEU A 1 86 ? -12.999 36.491 -15.827 1.00 23.03 ? 86 LEU A CD2 1 ATOM 628 N N . LEU A 1 87 ? -16.663 36.778 -12.639 1.00 19.48 ? 87 LEU A N 1 ATOM 629 C CA . LEU A 1 87 ? -17.920 36.285 -13.183 1.00 19.13 ? 87 LEU A CA 1 ATOM 630 C C . LEU A 1 87 ? -17.941 36.540 -14.690 1.00 18.43 ? 87 LEU A C 1 ATOM 631 O O . LEU A 1 87 ? -17.742 37.668 -15.141 1.00 18.09 ? 87 LEU A O 1 ATOM 632 C CB . LEU A 1 87 ? -19.089 37.013 -12.498 1.00 17.62 ? 87 LEU A CB 1 ATOM 633 C CG . LEU A 1 87 ? -20.511 36.720 -13.043 1.00 21.03 ? 87 LEU A CG 1 ATOM 634 C CD1 . LEU A 1 87 ? -20.910 35.275 -12.879 1.00 19.51 ? 87 LEU A CD1 1 ATOM 635 C CD2 . LEU A 1 87 ? -21.521 37.576 -12.330 1.00 20.03 ? 87 LEU A CD2 1 ATOM 636 N N . THR A 1 88 ? -18.170 35.488 -15.475 1.00 19.18 ? 88 THR A N 1 ATOM 637 C CA . THR A 1 88 ? -18.344 35.597 -16.901 1.00 19.09 ? 88 THR A CA 1 ATOM 638 C C . THR A 1 88 ? -19.732 35.023 -17.182 1.00 18.71 ? 88 THR A C 1 ATOM 639 O O . THR A 1 88 ? -20.015 33.887 -16.804 1.00 18.04 ? 88 THR A O 1 ATOM 640 C CB . THR A 1 88 ? -17.314 34.770 -17.625 1.00 20.04 ? 88 THR A CB 1 ATOM 641 O OG1 . THR A 1 88 ? -16.009 35.248 -17.289 1.00 23.44 ? 88 THR A OG1 1 ATOM 642 C CG2 . THR A 1 88 ? -17.488 34.858 -19.151 1.00 21.92 ? 88 THR A CG2 1 ATOM 643 N N . ALA A 1 89 ? -20.577 35.821 -17.831 1.00 17.68 ? 89 ALA A N 1 ATOM 644 C CA . ALA A 1 89 ? -21.965 35.447 -18.136 1.00 17.58 ? 89 ALA A CA 1 ATOM 645 C C . ALA A 1 89 ? -22.178 35.492 -19.628 1.00 17.87 ? 89 ALA A C 1 ATOM 646 O O . ALA A 1 89 ? -21.713 36.441 -20.316 1.00 17.66 ? 89 ALA A O 1 ATOM 647 C CB . ALA A 1 89 ? -22.909 36.420 -17.443 1.00 16.97 ? 89 ALA A CB 1 ATOM 648 N N . GLU A 1 90 ? -22.839 34.462 -20.170 1.00 17.74 ? 90 GLU A N 1 ATOM 649 C CA . GLU A 1 90 ? -23.042 34.390 -21.612 1.00 18.44 ? 90 GLU A CA 1 ATOM 650 C C . GLU A 1 90 ? -24.490 34.051 -21.883 1.00 18.65 ? 90 GLU A C 1 ATOM 651 O O . GLU A 1 90 ? -24.985 33.071 -21.352 1.00 17.59 ? 90 GLU A O 1 ATOM 652 C CB . GLU A 1 90 ? -22.145 33.317 -22.221 1.00 18.61 ? 90 GLU A CB 1 ATOM 653 C CG . GLU A 1 90 ? -20.637 33.586 -21.978 1.00 22.63 ? 90 GLU A CG 1 ATOM 654 C CD . GLU A 1 90 ? -19.779 32.425 -22.393 1.00 26.46 ? 90 GLU A CD 1 ATOM 655 O OE1 . GLU A 1 90 ? -20.276 31.277 -22.370 1.00 25.16 ? 90 GLU A OE1 1 ATOM 656 O OE2 . GLU A 1 90 ? -18.607 32.650 -22.779 1.00 31.15 ? 90 GLU A OE2 1 ATOM 657 N N . TYR A 1 91 ? -25.157 34.899 -22.668 1.00 18.63 ? 91 TYR A N 1 ATOM 658 C CA . TYR A 1 91 ? -26.537 34.656 -23.104 1.00 19.09 ? 91 TYR A CA 1 ATOM 659 C C . TYR A 1 91 ? -26.438 33.772 -24.327 1.00 17.80 ? 91 TYR A C 1 ATOM 660 O O . TYR A 1 91 ? -26.546 34.228 -25.474 1.00 17.71 ? 91 TYR A O 1 ATOM 661 C CB . TYR A 1 91 ? -27.225 35.976 -23.412 1.00 20.92 ? 91 TYR A CB 1 ATOM 662 C CG . TYR A 1 91 ? -27.318 36.951 -22.232 1.00 23.10 ? 91 TYR A CG 1 ATOM 663 C CD1 . TYR A 1 91 ? -28.269 36.781 -21.243 1.00 26.44 ? 91 TYR A CD1 1 ATOM 664 C CD2 . TYR A 1 91 ? -26.486 38.070 -22.135 1.00 25.86 ? 91 TYR A CD2 1 ATOM 665 C CE1 . TYR A 1 91 ? -28.388 37.689 -20.158 1.00 27.13 ? 91 TYR A CE1 1 ATOM 666 C CE2 . TYR A 1 91 ? -26.592 38.996 -21.043 1.00 26.83 ? 91 TYR A CE2 1 ATOM 667 C CZ . TYR A 1 91 ? -27.535 38.784 -20.060 1.00 27.40 ? 91 TYR A CZ 1 ATOM 668 O OH . TYR A 1 91 ? -27.692 39.666 -19.008 1.00 24.30 ? 91 TYR A OH 1 ATOM 669 N N . GLN A 1 92 ? -26.205 32.493 -24.078 1.00 16.40 ? 92 GLN A N 1 ATOM 670 C CA . GLN A 1 92 ? -25.887 31.559 -25.168 1.00 16.38 ? 92 GLN A CA 1 ATOM 671 C C . GLN A 1 92 ? -27.036 31.310 -26.145 1.00 15.42 ? 92 GLN A C 1 ATOM 672 O O . GLN A 1 92 ? -26.816 31.282 -27.351 1.00 15.35 ? 92 GLN A O 1 ATOM 673 C CB . GLN A 1 92 ? -25.400 30.248 -24.611 1.00 15.83 ? 92 GLN A CB 1 ATOM 674 C CG . GLN A 1 92 ? -24.063 30.387 -23.865 1.00 19.69 ? 92 GLN A CG 1 ATOM 675 C CD . GLN A 1 92 ? -23.432 29.028 -23.585 1.00 19.84 ? 92 GLN A CD 1 ATOM 676 O OE1 . GLN A 1 92 ? -24.096 27.990 -23.639 1.00 18.57 ? 92 GLN A OE1 1 ATOM 677 N NE2 . GLN A 1 92 ? -22.146 29.037 -23.291 1.00 18.86 ? 92 GLN A NE2 1 ATOM 678 N N . THR A 1 93 ? -28.239 31.126 -25.630 1.00 14.59 ? 93 THR A N 1 ATOM 679 C CA . THR A 1 93 ? -29.377 30.958 -26.518 1.00 15.42 ? 93 THR A CA 1 ATOM 680 C C . THR A 1 93 ? -30.557 31.585 -25.855 1.00 16.01 ? 93 THR A C 1 ATOM 681 O O . THR A 1 93 ? -30.484 32.016 -24.705 1.00 14.42 ? 93 THR A O 1 ATOM 682 C CB . THR A 1 93 ? -29.765 29.472 -26.772 1.00 16.89 ? 93 THR A CB 1 ATOM 683 O OG1 . THR A 1 93 ? -30.508 28.972 -25.650 1.00 17.93 ? 93 THR A OG1 1 ATOM 684 C CG2 . THR A 1 93 ? -28.617 28.570 -27.085 1.00 18.27 ? 93 THR A CG2 1 ATOM 685 N N . SER A 1 94 ? -31.679 31.646 -26.569 1.00 15.09 ? 94 SER A N 1 ATOM 686 C CA . SER A 1 94 ? -32.885 32.192 -25.966 1.00 16.96 ? 94 SER A CA 1 ATOM 687 C C . SER A 1 94 ? -33.326 31.438 -24.716 1.00 16.35 ? 94 SER A C 1 ATOM 688 O O . SER A 1 94 ? -34.064 32.007 -23.859 1.00 17.22 ? 94 SER A O 1 ATOM 689 C CB . SER A 1 94 ? -34.034 32.109 -26.989 1.00 17.54 ? 94 SER A CB 1 ATOM 690 O OG . SER A 1 94 ? -33.761 32.925 -28.104 1.00 24.23 ? 94 SER A OG 1 ATOM 691 N N . ASN A 1 95 ? -32.948 30.163 -24.628 1.00 15.00 ? 95 ASN A N 1 ATOM 692 C CA . ASN A 1 95 ? -33.378 29.342 -23.521 1.00 16.14 ? 95 ASN A CA 1 ATOM 693 C C . ASN A 1 95 ? -32.278 28.823 -22.614 1.00 15.99 ? 95 ASN A C 1 ATOM 694 O O . ASN A 1 95 ? -32.548 28.021 -21.737 1.00 16.14 ? 95 ASN A O 1 ATOM 695 C CB . ASN A 1 95 ? -34.215 28.162 -24.019 1.00 16.84 ? 95 ASN A CB 1 ATOM 696 C CG . ASN A 1 95 ? -35.459 28.610 -24.729 1.00 21.25 ? 95 ASN A CG 1 ATOM 697 O OD1 . ASN A 1 95 ? -36.555 28.568 -24.163 1.00 29.80 ? 95 ASN A OD1 1 ATOM 698 N ND2 . ASN A 1 95 ? -35.312 29.031 -25.961 1.00 21.91 ? 95 ASN A ND2 1 ATOM 699 N N . ARG A 1 96 ? -31.042 29.283 -22.807 1.00 15.69 ? 96 ARG A N 1 ATOM 700 C CA . ARG A 1 96 ? -29.927 28.713 -22.043 1.00 15.30 ? 96 ARG A CA 1 ATOM 701 C C . ARG A 1 96 ? -28.997 29.849 -21.652 1.00 15.39 ? 96 ARG A C 1 ATOM 702 O O . ARG A 1 96 ? -28.532 30.606 -22.515 1.00 16.81 ? 96 ARG A O 1 ATOM 703 C CB . ARG A 1 96 ? -29.127 27.684 -22.885 1.00 15.14 ? 96 ARG A CB 1 ATOM 704 C CG . ARG A 1 96 ? -27.956 27.095 -22.087 1.00 15.99 ? 96 ARG A CG 1 ATOM 705 C CD . ARG A 1 96 ? -27.232 26.022 -22.853 1.00 19.26 ? 96 ARG A CD 1 ATOM 706 N NE . ARG A 1 96 ? -26.348 26.496 -23.905 1.00 18.43 ? 96 ARG A NE 1 ATOM 707 C CZ . ARG A 1 96 ? -26.409 26.121 -25.179 1.00 21.73 ? 96 ARG A CZ 1 ATOM 708 N NH1 . ARG A 1 96 ? -27.379 25.302 -25.614 1.00 20.98 ? 96 ARG A NH1 1 ATOM 709 N NH2 . ARG A 1 96 ? -25.507 26.586 -26.044 1.00 21.58 ? 96 ARG A NH2 1 ATOM 710 N N . PHE A 1 97 ? -28.760 29.970 -20.353 1.00 14.79 ? 97 PHE A N 1 ATOM 711 C CA . PHE A 1 97 ? -27.878 30.954 -19.812 1.00 14.16 ? 97 PHE A CA 1 ATOM 712 C C . PHE A 1 97 ? -26.674 30.196 -19.262 1.00 15.16 ? 97 PHE A C 1 ATOM 713 O O . PHE A 1 97 ? -26.817 29.141 -18.663 1.00 15.81 ? 97 PHE A O 1 ATOM 714 C CB . PHE A 1 97 ? -28.594 31.741 -18.696 1.00 14.17 ? 97 PHE A CB 1 ATOM 715 C CG . PHE A 1 97 ? -27.722 32.776 -18.010 1.00 15.39 ? 97 PHE A CG 1 ATOM 716 C CD1 . PHE A 1 97 ? -27.147 33.842 -18.747 1.00 13.37 ? 97 PHE A CD1 1 ATOM 717 C CD2 . PHE A 1 97 ? -27.464 32.682 -16.666 1.00 13.70 ? 97 PHE A CD2 1 ATOM 718 C CE1 . PHE A 1 97 ? -26.334 34.775 -18.151 1.00 17.66 ? 97 PHE A CE1 1 ATOM 719 C CE2 . PHE A 1 97 ? -26.647 33.647 -16.039 1.00 16.70 ? 97 PHE A CE2 1 ATOM 720 C CZ . PHE A 1 97 ? -26.068 34.667 -16.781 1.00 15.89 ? 97 PHE A CZ 1 ATOM 721 N N . HIS A 1 98 ? -25.501 30.785 -19.407 1.00 15.78 ? 98 HIS A N 1 ATOM 722 C CA . HIS A 1 98 ? -24.322 30.148 -18.898 1.00 15.89 ? 98 HIS A CA 1 ATOM 723 C C . HIS A 1 98 ? -23.621 31.191 -18.020 1.00 15.33 ? 98 HIS A C 1 ATOM 724 O O . HIS A 1 98 ? -23.418 32.330 -18.441 1.00 14.97 ? 98 HIS A O 1 ATOM 725 C CB . HIS A 1 98 ? -23.500 29.722 -20.102 1.00 16.71 ? 98 HIS A CB 1 ATOM 726 C CG . HIS A 1 98 ? -22.120 29.261 -19.769 1.00 18.36 ? 98 HIS A CG 1 ATOM 727 N ND1 . HIS A 1 98 ? -21.862 28.354 -18.765 1.00 20.51 ? 98 HIS A ND1 1 ATOM 728 C CD2 . HIS A 1 98 ? -20.917 29.574 -20.319 1.00 19.74 ? 98 HIS A CD2 1 ATOM 729 C CE1 . HIS A 1 98 ? -20.553 28.129 -18.705 1.00 16.23 ? 98 HIS A CE1 1 ATOM 730 N NE2 . HIS A 1 98 ? -19.966 28.843 -19.647 1.00 22.45 ? 98 HIS A NE2 1 ATOM 731 N N . PHE A 1 99 ? -23.293 30.849 -16.785 1.00 16.18 ? 99 PHE A N 1 ATOM 732 C CA . PHE A 1 99 ? -22.356 31.715 -16.038 1.00 17.90 ? 99 PHE A CA 1 ATOM 733 C C . PHE A 1 99 ? -21.271 30.917 -15.337 1.00 18.80 ? 99 PHE A C 1 ATOM 734 O O . PHE A 1 99 ? -21.491 29.782 -14.919 1.00 19.07 ? 99 PHE A O 1 ATOM 735 C CB . PHE A 1 99 ? -23.072 32.672 -15.063 1.00 18.56 ? 99 PHE A CB 1 ATOM 736 C CG . PHE A 1 99 ? -23.707 31.999 -13.862 1.00 19.92 ? 99 PHE A CG 1 ATOM 737 C CD1 . PHE A 1 99 ? -23.027 31.923 -12.653 1.00 21.07 ? 99 PHE A CD1 1 ATOM 738 C CD2 . PHE A 1 99 ? -24.990 31.468 -13.942 1.00 20.66 ? 99 PHE A CD2 1 ATOM 739 C CE1 . PHE A 1 99 ? -23.609 31.305 -11.528 1.00 19.26 ? 99 PHE A CE1 1 ATOM 740 C CE2 . PHE A 1 99 ? -25.611 30.879 -12.807 1.00 22.27 ? 99 PHE A CE2 1 ATOM 741 C CZ . PHE A 1 99 ? -24.907 30.790 -11.611 1.00 21.80 ? 99 PHE A CZ 1 ATOM 742 N N . LYS A 1 100 ? -20.095 31.508 -15.219 1.00 19.12 ? 100 LYS A N 1 ATOM 743 C CA . LYS A 1 100 ? -19.010 30.841 -14.531 1.00 20.68 ? 100 LYS A CA 1 ATOM 744 C C . LYS A 1 100 ? -18.218 31.756 -13.616 1.00 20.08 ? 100 LYS A C 1 ATOM 745 O O . LYS A 1 100 ? -18.070 32.955 -13.873 1.00 20.27 ? 100 LYS A O 1 ATOM 746 C CB . LYS A 1 100 ? -18.130 30.048 -15.493 1.00 21.42 ? 100 LYS A CB 1 ATOM 747 C CG . LYS A 1 100 ? -17.239 30.837 -16.377 1.00 24.86 ? 100 LYS A CG 1 ATOM 748 C CD . LYS A 1 100 ? -16.445 29.928 -17.329 1.00 29.44 ? 100 LYS A CD 1 ATOM 749 C CE . LYS A 1 100 ? -15.686 30.832 -18.324 1.00 35.27 ? 100 LYS A CE 1 ATOM 750 N NZ . LYS A 1 100 ? -14.606 30.121 -19.051 1.00 37.51 ? 100 LYS A NZ 1 ATOM 751 N N . LEU A 1 101 ? -17.791 31.189 -12.497 1.00 18.97 ? 101 LEU A N 1 ATOM 752 C CA . LEU A 1 101 ? -17.085 31.970 -11.503 1.00 19.87 ? 101 LEU A CA 1 ATOM 753 C C . LEU A 1 101 ? -15.721 31.316 -11.479 1.00 19.60 ? 101 LEU A C 1 ATOM 754 O O . LEU A 1 101 ? -15.624 30.107 -11.280 1.00 19.63 ? 101 LEU A O 1 ATOM 755 C CB . LEU A 1 101 ? -17.758 31.876 -10.133 1.00 19.70 ? 101 LEU A CB 1 ATOM 756 C CG . LEU A 1 101 ? -19.172 32.502 -10.079 1.00 19.85 ? 101 LEU A CG 1 ATOM 757 C CD1 . LEU A 1 101 ? -19.912 31.992 -8.911 1.00 23.18 ? 101 LEU A CD1 1 ATOM 758 C CD2 . LEU A 1 101 ? -19.113 34.008 -10.014 1.00 20.59 ? 101 LEU A CD2 1 ATOM 759 N N . THR A 1 102 ? -14.695 32.099 -11.743 1.00 20.77 ? 102 THR A N 1 ATOM 760 C CA . THR A 1 102 ? -13.334 31.583 -11.803 1.00 21.63 ? 102 THR A CA 1 ATOM 761 C C . THR A 1 102 ? -12.446 32.447 -10.917 1.00 21.87 ? 102 THR A C 1 ATOM 762 O O . THR A 1 102 ? -12.882 33.475 -10.416 1.00 21.19 ? 102 THR A O 1 ATOM 763 C CB . THR A 1 102 ? -12.812 31.597 -13.267 1.00 22.31 ? 102 THR A CB 1 ATOM 764 O OG1 . THR A 1 102 ? -12.986 32.904 -13.828 1.00 23.06 ? 102 THR A OG1 1 ATOM 765 C CG2 . THR A 1 102 ? -13.598 30.608 -14.129 1.00 23.71 ? 102 THR A CG2 1 ATOM 766 N N . ASP A 1 103 ? -11.202 32.029 -10.729 1.00 22.47 ? 103 ASP A N 1 ATOM 767 C CA . ASP A 1 103 ? -10.197 32.841 -10.044 1.00 24.27 ? 103 ASP A CA 1 ATOM 768 C C . ASP A 1 103 ? -9.632 33.821 -11.071 1.00 25.18 ? 103 ASP A C 1 ATOM 769 O O . ASP A 1 103 ? -9.046 33.426 -12.071 1.00 24.53 ? 103 ASP A O 1 ATOM 770 C CB . ASP A 1 103 ? -9.097 31.936 -9.477 1.00 23.09 ? 103 ASP A CB 1 ATOM 771 C CG . ASP A 1 103 ? -8.050 32.701 -8.631 1.00 28.13 ? 103 ASP A CG 1 ATOM 772 O OD1 . ASP A 1 103 ? -7.912 33.941 -8.750 1.00 28.33 ? 103 ASP A OD1 1 ATOM 773 O OD2 . ASP A 1 103 ? -7.335 32.024 -7.850 1.00 30.17 ? 103 ASP A OD2 1 ATOM 774 N N . GLN A 1 104 ? -9.831 35.099 -10.818 1.00 27.79 ? 104 GLN A N 1 ATOM 775 C CA . GLN A 1 104 ? -9.464 36.155 -11.757 1.00 32.04 ? 104 GLN A CA 1 ATOM 776 C C . GLN A 1 104 ? -7.988 36.047 -12.127 1.00 32.52 ? 104 GLN A C 1 ATOM 777 O O . GLN A 1 104 ? -7.606 36.345 -13.262 1.00 33.27 ? 104 GLN A O 1 ATOM 778 C CB . GLN A 1 104 ? -9.758 37.487 -11.066 1.00 31.65 ? 104 GLN A CB 1 ATOM 779 C CG . GLN A 1 104 ? -10.070 38.706 -11.893 1.00 34.60 ? 104 GLN A CG 1 ATOM 780 C CD . GLN A 1 104 ? -10.423 39.857 -10.945 1.00 35.27 ? 104 GLN A CD 1 ATOM 781 O OE1 . GLN A 1 104 ? -11.551 39.937 -10.421 1.00 40.66 ? 104 GLN A OE1 1 ATOM 782 N NE2 . GLN A 1 104 ? -9.445 40.701 -10.656 1.00 37.91 ? 104 GLN A NE2 1 ATOM 783 N N . THR A 1 105 ? -7.175 35.569 -11.173 1.00 34.35 ? 105 THR A N 1 ATOM 784 C CA . THR A 1 105 ? -5.709 35.614 -11.262 1.00 36.31 ? 105 THR A CA 1 ATOM 785 C C . THR A 1 105 ? -5.036 34.256 -11.471 1.00 36.14 ? 105 THR A C 1 ATOM 786 O O . THR A 1 105 ? -3.831 34.207 -11.671 1.00 37.43 ? 105 THR A O 1 ATOM 787 C CB . THR A 1 105 ? -5.071 36.248 -9.989 1.00 36.68 ? 105 THR A CB 1 ATOM 788 O OG1 . THR A 1 105 ? -5.004 35.263 -8.951 1.00 40.24 ? 105 THR A OG1 1 ATOM 789 C CG2 . THR A 1 105 ? -5.879 37.436 -9.485 1.00 37.98 ? 105 THR A CG2 1 ATOM 790 N N . ASN A 1 106 ? -5.786 33.154 -11.401 1.00 35.37 ? 106 ASN A N 1 ATOM 791 C CA . ASN A 1 106 ? -5.217 31.831 -11.673 1.00 34.76 ? 106 ASN A CA 1 ATOM 792 C C . ASN A 1 106 ? -6.145 30.919 -12.471 1.00 33.04 ? 106 ASN A C 1 ATOM 793 O O . ASN A 1 106 ? -7.354 30.888 -12.247 1.00 32.67 ? 106 ASN A O 1 ATOM 794 C CB . ASN A 1 106 ? -4.843 31.114 -10.375 1.00 35.94 ? 106 ASN A CB 1 ATOM 795 C CG . ASN A 1 106 ? -3.808 31.874 -9.551 1.00 39.47 ? 106 ASN A CG 1 ATOM 796 O OD1 . ASN A 1 106 ? -4.125 32.399 -8.473 1.00 43.75 ? 106 ASN A OD1 1 ATOM 797 N ND2 . ASN A 1 106 ? -2.567 31.924 -10.039 1.00 42.39 ? 106 ASN A ND2 1 ATOM 798 N N . ASN A 1 107 ? -5.565 30.165 -13.385 1.00 31.06 ? 107 ASN A N 1 ATOM 799 C CA . ASN A 1 107 ? -6.281 29.112 -14.064 1.00 29.88 ? 107 ASN A CA 1 ATOM 800 C C . ASN A 1 107 ? -6.602 27.983 -13.086 1.00 27.91 ? 107 ASN A C 1 ATOM 801 O O . ASN A 1 107 ? -5.753 27.580 -12.306 1.00 28.54 ? 107 ASN A O 1 ATOM 802 C CB . ASN A 1 107 ? -5.458 28.589 -15.249 1.00 30.72 ? 107 ASN A CB 1 ATOM 803 C CG . ASN A 1 107 ? -5.359 29.615 -16.392 1.00 34.58 ? 107 ASN A CG 1 ATOM 804 O OD1 . ASN A 1 107 ? -4.276 29.866 -16.910 1.00 41.64 ? 107 ASN A OD1 1 ATOM 805 N ND2 . ASN A 1 107 ? -6.490 30.215 -16.773 1.00 37.06 ? 107 ASN A ND2 1 ATOM 806 N N . ARG A 1 108 ? -7.842 27.508 -13.099 1.00 24.10 ? 108 ARG A N 1 ATOM 807 C CA . ARG A 1 108 ? -8.232 26.385 -12.255 1.00 21.23 ? 108 ARG A CA 1 ATOM 808 C C . ARG A 1 108 ? -8.741 25.239 -13.139 1.00 19.78 ? 108 ARG A C 1 ATOM 809 O O . ARG A 1 108 ? -8.995 25.435 -14.322 1.00 18.91 ? 108 ARG A O 1 ATOM 810 C CB . ARG A 1 108 ? -9.306 26.803 -11.238 1.00 21.13 ? 108 ARG A CB 1 ATOM 811 C CG . ARG A 1 108 ? -8.852 27.854 -10.251 1.00 18.62 ? 108 ARG A CG 1 ATOM 812 C CD . ARG A 1 108 ? -9.971 28.282 -9.345 1.00 17.17 ? 108 ARG A CD 1 ATOM 813 N NE . ARG A 1 108 ? -10.585 27.128 -8.683 1.00 17.24 ? 108 ARG A NE 1 ATOM 814 C CZ . ARG A 1 108 ? -10.087 26.510 -7.615 1.00 21.88 ? 108 ARG A CZ 1 ATOM 815 N NH1 . ARG A 1 108 ? -8.965 26.955 -7.013 1.00 17.92 ? 108 ARG A NH1 1 ATOM 816 N NH2 . ARG A 1 108 ? -10.727 25.450 -7.121 1.00 18.75 ? 108 ARG A NH2 1 ATOM 817 N N . PHE A 1 109 ? -8.889 24.041 -12.566 1.00 18.62 ? 109 PHE A N 1 ATOM 818 C CA . PHE A 1 109 ? -9.268 22.896 -13.359 1.00 17.33 ? 109 PHE A CA 1 ATOM 819 C C . PHE A 1 109 ? -10.703 23.125 -13.899 1.00 17.46 ? 109 PHE A C 1 ATOM 820 O O . PHE A 1 109 ? -11.575 23.509 -13.130 1.00 16.75 ? 109 PHE A O 1 ATOM 821 C CB . PHE A 1 109 ? -9.249 21.601 -12.525 1.00 17.79 ? 109 PHE A CB 1 ATOM 822 C CG . PHE A 1 109 ? -9.856 20.440 -13.256 1.00 16.49 ? 109 PHE A CG 1 ATOM 823 C CD1 . PHE A 1 109 ? -9.104 19.736 -14.192 1.00 19.95 ? 109 PHE A CD1 1 ATOM 824 C CD2 . PHE A 1 109 ? -11.213 20.135 -13.095 1.00 17.09 ? 109 PHE A CD2 1 ATOM 825 C CE1 . PHE A 1 109 ? -9.677 18.697 -14.921 1.00 19.14 ? 109 PHE A CE1 1 ATOM 826 C CE2 . PHE A 1 109 ? -11.806 19.104 -13.819 1.00 16.69 ? 109 PHE A CE2 1 ATOM 827 C CZ . PHE A 1 109 ? -11.025 18.372 -14.721 1.00 17.41 ? 109 PHE A CZ 1 ATOM 828 N N . GLU A 1 110 ? -10.910 22.912 -15.194 1.00 18.21 ? 110 GLU A N 1 ATOM 829 C CA . GLU A 1 110 ? -12.254 23.001 -15.798 1.00 19.00 ? 110 GLU A CA 1 ATOM 830 C C . GLU A 1 110 ? -12.471 21.699 -16.516 1.00 19.64 ? 110 GLU A C 1 ATOM 831 O O . GLU A 1 110 ? -11.522 21.187 -17.116 1.00 19.53 ? 110 GLU A O 1 ATOM 832 C CB . GLU A 1 110 ? -12.266 24.180 -16.773 1.00 19.98 ? 110 GLU A CB 1 ATOM 833 C CG . GLU A 1 110 ? -12.054 25.496 -16.046 1.00 22.13 ? 110 GLU A CG 1 ATOM 834 C CD . GLU A 1 110 ? -12.329 26.715 -16.889 1.00 32.09 ? 110 GLU A CD 1 ATOM 835 O OE1 . GLU A 1 110 ? -13.388 26.762 -17.578 1.00 36.51 ? 110 GLU A OE1 1 ATOM 836 O OE2 . GLU A 1 110 ? -11.505 27.650 -16.805 1.00 32.36 ? 110 GLU A OE2 1 ATOM 837 N N . VAL A 1 111 ? -13.692 21.141 -16.466 1.00 18.55 ? 111 VAL A N 1 ATOM 838 C CA . VAL A 1 111 ? -13.955 19.826 -17.053 1.00 17.79 ? 111 VAL A CA 1 ATOM 839 C C . VAL A 1 111 ? -13.673 19.845 -18.550 1.00 18.89 ? 111 VAL A C 1 ATOM 840 O O . VAL A 1 111 ? -14.261 20.646 -19.278 1.00 19.29 ? 111 VAL A O 1 ATOM 841 C CB . VAL A 1 111 ? -15.427 19.385 -16.815 1.00 18.20 ? 111 VAL A CB 1 ATOM 842 C CG1 . VAL A 1 111 ? -15.722 18.058 -17.505 1.00 16.78 ? 111 VAL A CG1 1 ATOM 843 C CG2 . VAL A 1 111 ? -15.716 19.310 -15.322 1.00 17.85 ? 111 VAL A CG2 1 ATOM 844 N N . PRO A 1 112 ? -12.787 18.958 -19.041 1.00 18.54 ? 112 PRO A N 1 ATOM 845 C CA . PRO A 1 112 ? -12.532 18.936 -20.477 1.00 20.02 ? 112 PRO A CA 1 ATOM 846 C C . PRO A 1 112 ? -13.585 18.115 -21.226 1.00 20.24 ? 112 PRO A C 1 ATOM 847 O O . PRO A 1 112 ? -13.285 17.077 -21.807 1.00 21.17 ? 112 PRO A O 1 ATOM 848 C CB . PRO A 1 112 ? -11.161 18.270 -20.585 1.00 20.22 ? 112 PRO A CB 1 ATOM 849 C CG . PRO A 1 112 ? -11.021 17.486 -19.392 1.00 20.06 ? 112 PRO A CG 1 ATOM 850 C CD . PRO A 1 112 ? -11.941 17.990 -18.314 1.00 19.87 ? 112 PRO A CD 1 ATOM 851 N N . HIS A 1 113 ? -14.823 18.572 -21.178 1.00 20.29 ? 113 HIS A N 1 ATOM 852 C CA . HIS A 1 113 ? -15.902 17.803 -21.780 1.00 19.59 ? 113 HIS A CA 1 ATOM 853 C C . HIS A 1 113 ? -15.700 17.531 -23.273 1.00 20.03 ? 113 HIS A C 1 ATOM 854 O O . HIS A 1 113 ? -15.178 18.379 -23.993 1.00 19.60 ? 113 HIS A O 1 ATOM 855 C CB . HIS A 1 113 ? -17.208 18.524 -21.559 1.00 19.59 ? 113 HIS A CB 1 ATOM 856 C CG . HIS A 1 113 ? -18.371 17.604 -21.571 1.00 21.15 ? 113 HIS A CG 1 ATOM 857 N ND1 . HIS A 1 113 ? -19.188 17.459 -22.673 1.00 20.44 ? 113 HIS A ND1 1 ATOM 858 C CD2 . HIS A 1 113 ? -18.827 16.731 -20.640 1.00 21.37 ? 113 HIS A CD2 1 ATOM 859 C CE1 . HIS A 1 113 ? -20.131 16.572 -22.397 1.00 19.45 ? 113 HIS A CE1 1 ATOM 860 N NE2 . HIS A 1 113 ? -19.930 16.111 -21.175 1.00 19.08 ? 113 HIS A NE2 1 ATOM 861 N N . GLU A 1 114 ? -16.126 16.355 -23.734 1.00 20.07 ? 114 GLU A N 1 ATOM 862 C CA . GLU A 1 114 ? -15.909 15.951 -25.110 1.00 21.24 ? 114 GLU A CA 1 ATOM 863 C C . GLU A 1 114 ? -16.936 16.623 -26.012 1.00 21.55 ? 114 GLU A C 1 ATOM 864 O O . GLU A 1 114 ? -16.638 16.894 -27.155 1.00 22.11 ? 114 GLU A O 1 ATOM 865 C CB . GLU A 1 114 ? -15.973 14.430 -25.248 1.00 21.90 ? 114 GLU A CB 1 ATOM 866 C CG . GLU A 1 114 ? -15.755 13.829 -26.652 1.00 24.87 ? 114 GLU A CG 1 ATOM 867 C CD . GLU A 1 114 ? -16.982 13.929 -27.575 1.00 28.93 ? 114 GLU A CD 1 ATOM 868 O OE1 . GLU A 1 114 ? -18.134 14.081 -27.104 1.00 25.62 ? 114 GLU A OE1 1 ATOM 869 O OE2 . GLU A 1 114 ? -16.788 13.849 -28.796 1.00 31.94 ? 114 GLU A OE2 1 ATOM 870 N N . HIS A 1 115 ? -18.138 16.890 -25.513 1.00 20.20 ? 115 HIS A N 1 ATOM 871 C CA . HIS A 1 115 ? -19.153 17.482 -26.388 1.00 20.97 ? 115 HIS A CA 1 ATOM 872 C C . HIS A 1 115 ? -19.218 19.013 -26.271 1.00 21.24 ? 115 HIS A C 1 ATOM 873 O O . HIS A 1 115 ? -19.293 19.733 -27.279 1.00 21.42 ? 115 HIS A O 1 ATOM 874 C CB . HIS A 1 115 ? -20.527 16.862 -26.089 1.00 20.04 ? 115 HIS A CB 1 ATOM 875 C CG . HIS A 1 115 ? -21.593 17.258 -27.061 1.00 21.67 ? 115 HIS A CG 1 ATOM 876 N ND1 . HIS A 1 115 ? -21.709 16.677 -28.306 1.00 23.40 ? 115 HIS A ND1 1 ATOM 877 C CD2 . HIS A 1 115 ? -22.595 18.165 -26.970 1.00 19.95 ? 115 HIS A CD2 1 ATOM 878 C CE1 . HIS A 1 115 ? -22.733 17.215 -28.948 1.00 23.19 ? 115 HIS A CE1 1 ATOM 879 N NE2 . HIS A 1 115 ? -23.287 18.125 -28.160 1.00 21.04 ? 115 HIS A NE2 1 ATOM 880 N N . VAL A 1 116 ? -19.269 19.511 -25.039 1.00 21.22 ? 116 VAL A N 1 ATOM 881 C CA . VAL A 1 116 ? -19.506 20.917 -24.788 1.00 21.23 ? 116 VAL A CA 1 ATOM 882 C C . VAL A 1 116 ? -18.312 21.698 -25.315 1.00 23.43 ? 116 VAL A C 1 ATOM 883 O O . VAL A 1 116 ? -17.168 21.286 -25.117 1.00 22.94 ? 116 VAL A O 1 ATOM 884 C CB . VAL A 1 116 ? -19.737 21.175 -23.297 1.00 21.30 ? 116 VAL A CB 1 ATOM 885 C CG1 . VAL A 1 116 ? -19.734 22.679 -22.954 1.00 19.51 ? 116 VAL A CG1 1 ATOM 886 C CG2 . VAL A 1 116 ? -21.044 20.504 -22.855 1.00 18.82 ? 116 VAL A CG2 1 ATOM 887 N N . GLN A 1 117 ? -18.602 22.775 -26.037 1.00 24.64 ? 117 GLN A N 1 ATOM 888 C CA . GLN A 1 117 ? -17.569 23.667 -26.572 1.00 28.39 ? 117 GLN A CA 1 ATOM 889 C C . GLN A 1 117 ? -17.626 25.010 -25.908 1.00 28.32 ? 117 GLN A C 1 ATOM 890 O O . GLN A 1 117 ? -18.675 25.406 -25.401 1.00 28.44 ? 117 GLN A O 1 ATOM 891 C CB . GLN A 1 117 ? -17.778 23.875 -28.055 1.00 28.33 ? 117 GLN A CB 1 ATOM 892 C CG . GLN A 1 117 ? -17.492 22.667 -28.894 1.00 33.26 ? 117 GLN A CG 1 ATOM 893 C CD . GLN A 1 117 ? -17.330 23.092 -30.336 1.00 41.26 ? 117 GLN A CD 1 ATOM 894 O OE1 . GLN A 1 117 ? -18.302 23.494 -30.982 1.00 45.47 ? 117 GLN A OE1 1 ATOM 895 N NE2 . GLN A 1 117 ? -16.089 23.074 -30.834 1.00 42.14 ? 117 GLN A NE2 1 ATOM 896 N N . SER A 1 118 ? -16.501 25.722 -25.923 1.00 29.74 ? 118 SER A N 1 ATOM 897 C CA . SER A 1 118 ? -16.526 27.100 -25.465 1.00 30.86 ? 118 SER A CA 1 ATOM 898 C C . SER A 1 118 ? -17.351 27.909 -26.451 1.00 30.24 ? 118 SER A C 1 ATOM 899 O O . SER A 1 118 ? -17.402 27.631 -27.657 1.00 28.81 ? 118 SER A O 1 ATOM 900 C CB . SER A 1 118 ? -15.124 27.677 -25.271 1.00 31.37 ? 118 SER A CB 1 ATOM 901 O OG . SER A 1 118 ? -14.453 27.627 -26.498 1.00 35.55 ? 118 SER A OG 1 ATOM 902 N N . PHE A 1 119 ? -18.060 28.866 -25.894 1.00 30.67 ? 119 PHE A N 1 ATOM 903 C CA . PHE A 1 119 ? -18.892 29.740 -26.651 1.00 32.15 ? 119 PHE A CA 1 ATOM 904 C C . PHE A 1 119 ? -18.073 30.846 -27.292 1.00 33.43 ? 119 PHE A C 1 ATOM 905 O O . PHE A 1 119 ? -17.263 31.497 -26.645 1.00 33.48 ? 119 PHE A O 1 ATOM 906 C CB . PHE A 1 119 ? -19.920 30.338 -25.708 1.00 31.61 ? 119 PHE A CB 1 ATOM 907 C CG . PHE A 1 119 ? -20.955 31.133 -26.384 1.00 30.58 ? 119 PHE A CG 1 ATOM 908 C CD1 . PHE A 1 119 ? -21.882 30.525 -27.223 1.00 30.28 ? 119 PHE A CD1 1 ATOM 909 C CD2 . PHE A 1 119 ? -21.028 32.493 -26.186 1.00 30.03 ? 119 PHE A CD2 1 ATOM 910 C CE1 . PHE A 1 119 ? -22.861 31.270 -27.853 1.00 30.12 ? 119 PHE A CE1 1 ATOM 911 C CE2 . PHE A 1 119 ? -22.018 33.254 -26.827 1.00 30.94 ? 119 PHE A CE2 1 ATOM 912 C CZ . PHE A 1 119 ? -22.934 32.632 -27.656 1.00 30.56 ? 119 PHE A CZ 1 ATOM 913 N N . SER A 1 120 ? -18.284 31.047 -28.580 1.00 35.30 ? 120 SER A N 1 ATOM 914 C CA . SER A 1 120 ? -17.765 32.236 -29.264 1.00 36.88 ? 120 SER A CA 1 ATOM 915 C C . SER A 1 120 ? -18.976 32.814 -29.961 1.00 37.33 ? 120 SER A C 1 ATOM 916 O O . SER A 1 120 ? -19.939 32.097 -30.261 1.00 38.53 ? 120 SER A O 1 ATOM 917 C CB . SER A 1 120 ? -16.679 31.847 -30.272 1.00 37.23 ? 120 SER A CB 1 ATOM 918 O OG . SER A 1 120 ? -17.121 30.740 -31.051 1.00 40.07 ? 120 SER A OG 1 ATOM 919 N N . GLY A 1 121 ? -18.990 34.108 -30.198 1.00 37.51 ? 121 GLY A N 1 ATOM 920 C CA . GLY A 1 121 ? -20.213 34.663 -30.780 1.00 36.76 ? 121 GLY A CA 1 ATOM 921 C C . GLY A 1 121 ? -21.014 35.485 -29.792 1.00 35.43 ? 121 GLY A C 1 ATOM 922 O O . GLY A 1 121 ? -20.542 35.820 -28.708 1.00 34.66 ? 121 GLY A O 1 ATOM 923 N N . ASN A 1 122 ? -22.235 35.822 -30.178 1.00 33.93 ? 122 ASN A N 1 ATOM 924 C CA . ASN A 1 122 ? -22.860 36.973 -29.584 1.00 31.91 ? 122 ASN A CA 1 ATOM 925 C C . ASN A 1 122 ? -24.057 36.585 -28.767 1.00 29.66 ? 122 ASN A C 1 ATOM 926 O O . ASN A 1 122 ? -24.697 35.593 -29.065 1.00 28.92 ? 122 ASN A O 1 ATOM 927 C CB . ASN A 1 122 ? -23.276 37.941 -30.693 1.00 33.11 ? 122 ASN A CB 1 ATOM 928 C CG . ASN A 1 122 ? -22.095 38.424 -31.511 1.00 35.62 ? 122 ASN A CG 1 ATOM 929 O OD1 . ASN A 1 122 ? -21.013 38.687 -30.978 1.00 37.66 ? 122 ASN A OD1 1 ATOM 930 N ND2 . ASN A 1 122 ? -22.293 38.524 -32.814 1.00 36.47 ? 122 ASN A ND2 1 ATOM 931 N N . ALA A 1 123 ? -24.365 37.402 -27.774 1.00 27.43 ? 123 ALA A N 1 ATOM 932 C CA . ALA A 1 123 ? -25.541 37.216 -26.938 1.00 26.25 ? 123 ALA A CA 1 ATOM 933 C C . ALA A 1 123 ? -26.767 36.938 -27.820 1.00 26.54 ? 123 ALA A C 1 ATOM 934 O O . ALA A 1 123 ? -26.926 37.543 -28.896 1.00 25.51 ? 123 ALA A O 1 ATOM 935 C CB . ALA A 1 123 ? -25.750 38.428 -26.084 1.00 26.13 ? 123 ALA A CB 1 ATOM 936 N N . ALA A 1 124 ? -27.630 36.026 -27.381 1.00 25.82 ? 124 ALA A N 1 ATOM 937 C CA . ALA A 1 124 ? -28.774 35.636 -28.187 1.00 25.54 ? 124 ALA A CA 1 ATOM 938 C C . ALA A 1 124 ? -29.847 36.709 -28.130 1.00 26.20 ? 124 ALA A C 1 ATOM 939 O O . ALA A 1 124 ? -29.943 37.431 -27.157 1.00 26.60 ? 124 ALA A O 1 ATOM 940 C CB . ALA A 1 124 ? -29.333 34.321 -27.720 1.00 24.93 ? 124 ALA A CB 1 ATOM 941 N N . ALA A 1 125 ? -30.637 36.794 -29.188 1.00 26.88 ? 125 ALA A N 1 ATOM 942 C CA . ALA A 1 125 ? -31.797 37.671 -29.257 1.00 28.27 ? 125 ALA A CA 1 ATOM 943 C C . ALA A 1 125 ? -33.014 36.963 -28.641 1.00 28.53 ? 125 ALA A C 1 ATOM 944 O O . ALA A 1 125 ? -33.037 35.722 -28.523 1.00 30.11 ? 125 ALA A O 1 ATOM 945 C CB . ALA A 1 125 ? -32.071 38.032 -30.744 1.00 28.72 ? 125 ALA A CB 1 ATOM 946 N N . SER A 1 126 ? -34.024 37.730 -28.234 1.00 28.37 ? 126 SER A N 1 ATOM 947 C CA . SER A 1 126 ? -35.305 37.155 -27.812 1.00 28.04 ? 126 SER A CA 1 ATOM 948 C C . SER A 1 126 ? -35.146 36.197 -26.644 1.00 26.75 ? 126 SER A C 1 ATOM 949 O O . SER A 1 126 ? -35.614 35.050 -26.700 1.00 27.41 ? 126 SER A O 1 ATOM 950 C CB . SER A 1 126 ? -35.991 36.438 -28.976 1.00 28.07 ? 126 SER A CB 1 ATOM 951 O OG . SER A 1 126 ? -36.153 37.325 -30.077 1.00 32.06 ? 126 SER A OG 1 ATOM 952 N N . LEU A 1 127 ? -34.488 36.656 -25.583 1.00 24.70 ? 127 LEU A N 1 ATOM 953 C CA . LEU A 1 127 ? -34.256 35.792 -24.424 1.00 22.70 ? 127 LEU A CA 1 ATOM 954 C C . LEU A 1 127 ? -35.575 35.490 -23.725 1.00 22.50 ? 127 LEU A C 1 ATOM 955 O O . LEU A 1 127 ? -36.416 36.371 -23.602 1.00 23.22 ? 127 LEU A O 1 ATOM 956 C CB . LEU A 1 127 ? -33.336 36.484 -23.450 1.00 22.61 ? 127 LEU A CB 1 ATOM 957 C CG . LEU A 1 127 ? -31.966 36.864 -24.032 1.00 19.91 ? 127 LEU A CG 1 ATOM 958 C CD1 . LEU A 1 127 ? -31.168 37.605 -22.969 1.00 25.73 ? 127 LEU A CD1 1 ATOM 959 C CD2 . LEU A 1 127 ? -31.253 35.643 -24.506 1.00 19.77 ? 127 LEU A CD2 1 ATOM 960 N N . THR A 1 128 ? -35.748 34.262 -23.249 1.00 21.04 ? 128 THR A N 1 ATOM 961 C CA . THR A 1 128 ? -36.921 33.926 -22.421 1.00 20.46 ? 128 THR A CA 1 ATOM 962 C C . THR A 1 128 ? -36.646 34.257 -20.961 1.00 19.31 ? 128 THR A C 1 ATOM 963 O O . THR A 1 128 ? -37.485 34.103 -20.097 1.00 16.98 ? 128 THR A O 1 ATOM 964 C CB . THR A 1 128 ? -37.279 32.437 -22.561 1.00 21.00 ? 128 THR A CB 1 ATOM 965 O OG1 . THR A 1 128 ? -36.197 31.639 -22.081 1.00 22.69 ? 128 THR A OG1 1 ATOM 966 C CG2 . THR A 1 128 ? -37.503 32.098 -23.991 1.00 21.34 ? 128 THR A CG2 1 ATOM 967 N N . TYR A 1 129 ? -35.413 34.672 -20.658 1.00 18.16 ? 129 TYR A N 1 ATOM 968 C CA . TYR A 1 129 ? -35.052 34.942 -19.271 1.00 18.41 ? 129 TYR A CA 1 ATOM 969 C C . TYR A 1 129 ? -34.389 36.337 -19.122 1.00 18.32 ? 129 TYR A C 1 ATOM 970 O O . TYR A 1 129 ? -33.955 36.943 -20.119 1.00 17.14 ? 129 TYR A O 1 ATOM 971 C CB . TYR A 1 129 ? -34.093 33.868 -18.742 1.00 18.04 ? 129 TYR A CB 1 ATOM 972 C CG . TYR A 1 129 ? -32.860 33.738 -19.599 1.00 16.77 ? 129 TYR A CG 1 ATOM 973 C CD1 . TYR A 1 129 ? -31.709 34.477 -19.316 1.00 18.45 ? 129 TYR A CD1 1 ATOM 974 C CD2 . TYR A 1 129 ? -32.841 32.880 -20.694 1.00 16.88 ? 129 TYR A CD2 1 ATOM 975 C CE1 . TYR A 1 129 ? -30.580 34.382 -20.145 1.00 14.58 ? 129 TYR A CE1 1 ATOM 976 C CE2 . TYR A 1 129 ? -31.696 32.765 -21.517 1.00 15.34 ? 129 TYR A CE2 1 ATOM 977 C CZ . TYR A 1 129 ? -30.586 33.506 -21.217 1.00 15.96 ? 129 TYR A CZ 1 ATOM 978 O OH . TYR A 1 129 ? -29.461 33.377 -22.036 1.00 19.66 ? 129 TYR A OH 1 ATOM 979 N N . GLN A 1 130 ? -34.290 36.805 -17.879 1.00 18.13 ? 130 GLN A N 1 ATOM 980 C CA . GLN A 1 130 ? -33.529 38.016 -17.569 1.00 20.81 ? 130 GLN A CA 1 ATOM 981 C C . GLN A 1 130 ? -32.552 37.693 -16.443 1.00 19.81 ? 130 GLN A C 1 ATOM 982 O O . GLN A 1 130 ? -32.838 36.862 -15.592 1.00 21.00 ? 130 GLN A O 1 ATOM 983 C CB . GLN A 1 130 ? -34.481 39.117 -17.124 1.00 21.22 ? 130 GLN A CB 1 ATOM 984 C CG . GLN A 1 130 ? -33.926 40.513 -17.080 1.00 27.53 ? 130 GLN A CG 1 ATOM 985 C CD . GLN A 1 130 ? -35.012 41.517 -16.743 1.00 35.39 ? 130 GLN A CD 1 ATOM 986 O OE1 . GLN A 1 130 ? -36.212 41.265 -16.988 1.00 37.53 ? 130 GLN A OE1 1 ATOM 987 N NE2 . GLN A 1 130 ? -34.612 42.659 -16.176 1.00 37.65 ? 130 GLN A NE2 1 ATOM 988 N N . VAL A 1 131 ? -31.410 38.348 -16.443 1.00 19.10 ? 131 VAL A N 1 ATOM 989 C CA . VAL A 1 131 ? -30.403 38.130 -15.413 1.00 18.50 ? 131 VAL A CA 1 ATOM 990 C C . VAL A 1 131 ? -30.263 39.449 -14.652 1.00 20.08 ? 131 VAL A C 1 ATOM 991 O O . VAL A 1 131 ? -30.328 40.539 -15.246 1.00 19.34 ? 131 VAL A O 1 ATOM 992 C CB . VAL A 1 131 ? -29.105 37.695 -16.043 1.00 17.37 ? 131 VAL A CB 1 ATOM 993 C CG1 . VAL A 1 131 ? -27.966 37.487 -14.957 1.00 17.22 ? 131 VAL A CG1 1 ATOM 994 C CG2 . VAL A 1 131 ? -29.374 36.393 -16.859 1.00 18.50 ? 131 VAL A CG2 1 ATOM 995 N N . GLU A 1 132 ? -30.128 39.350 -13.337 1.00 19.88 ? 132 GLU A N 1 ATOM 996 C CA . GLU A 1 132 ? -29.993 40.519 -12.487 1.00 21.88 ? 132 GLU A CA 1 ATOM 997 C C . GLU A 1 132 ? -28.832 40.241 -11.528 1.00 21.58 ? 132 GLU A C 1 ATOM 998 O O . GLU A 1 132 ? -28.762 39.172 -10.906 1.00 20.97 ? 132 GLU A O 1 ATOM 999 C CB . GLU A 1 132 ? -31.314 40.760 -11.756 1.00 24.05 ? 132 GLU A CB 1 ATOM 1000 C CG . GLU A 1 132 ? -31.220 41.549 -10.478 1.00 32.44 ? 132 GLU A CG 1 ATOM 1001 C CD . GLU A 1 132 ? -31.487 43.050 -10.631 1.00 41.26 ? 132 GLU A CD 1 ATOM 1002 O OE1 . GLU A 1 132 ? -31.788 43.529 -11.774 1.00 45.43 ? 132 GLU A OE1 1 ATOM 1003 O OE2 . GLU A 1 132 ? -31.408 43.739 -9.574 1.00 42.86 ? 132 GLU A OE2 1 ATOM 1004 N N . ILE A 1 133 ? -27.927 41.196 -11.419 1.00 19.03 ? 133 ILE A N 1 ATOM 1005 C CA . ILE A 1 133 ? -26.775 41.065 -10.522 1.00 19.05 ? 133 ILE A CA 1 ATOM 1006 C C . ILE A 1 133 ? -26.916 42.113 -9.422 1.00 19.04 ? 133 ILE A C 1 ATOM 1007 O O . ILE A 1 133 ? -27.149 43.293 -9.715 1.00 17.89 ? 133 ILE A O 1 ATOM 1008 C CB . ILE A 1 133 ? -25.483 41.294 -11.317 1.00 18.79 ? 133 ILE A CB 1 ATOM 1009 C CG1 . ILE A 1 133 ? -25.382 40.323 -12.506 1.00 19.00 ? 133 ILE A CG1 1 ATOM 1010 C CG2 . ILE A 1 133 ? -24.169 41.226 -10.404 1.00 18.13 ? 133 ILE A CG2 1 ATOM 1011 C CD1 . ILE A 1 133 ? -25.193 38.828 -12.114 1.00 22.71 ? 133 ILE A CD1 1 ATOM 1012 N N . SER A 1 134 ? -26.813 41.678 -8.163 1.00 19.25 ? 134 SER A N 1 ATOM 1013 C CA . SER A 1 134 ? -26.719 42.566 -7.017 1.00 21.89 ? 134 SER A CA 1 ATOM 1014 C C . SER A 1 134 ? -25.259 42.634 -6.649 1.00 23.46 ? 134 SER A C 1 ATOM 1015 O O . SER A 1 134 ? -24.567 41.648 -6.760 1.00 22.79 ? 134 SER A O 1 ATOM 1016 C CB . SER A 1 134 ? -27.529 42.029 -5.850 1.00 22.23 ? 134 SER A CB 1 ATOM 1017 O OG . SER A 1 134 ? -28.929 42.145 -6.174 1.00 27.04 ? 134 SER A OG 1 ATOM 1018 N N . ARG A 1 135 ? -24.816 43.794 -6.186 1.00 26.03 ? 135 ARG A N 1 ATOM 1019 C CA . ARG A 1 135 ? -23.416 44.077 -5.986 1.00 28.15 ? 135 ARG A CA 1 ATOM 1020 C C . ARG A 1 135 ? -22.970 43.880 -4.554 1.00 28.29 ? 135 ARG A C 1 ATOM 1021 O O . ARG A 1 135 ? -21.850 43.465 -4.295 1.00 28.39 ? 135 ARG A O 1 ATOM 1022 C CB . ARG A 1 135 ? -23.171 45.569 -6.221 1.00 31.23 ? 135 ARG A CB 1 ATOM 1023 C CG . ARG A 1 135 ? -23.190 46.135 -7.633 1.00 35.45 ? 135 ARG A CG 1 ATOM 1024 C CD . ARG A 1 135 ? -23.055 47.630 -7.439 1.00 41.56 ? 135 ARG A CD 1 ATOM 1025 N NE . ARG A 1 135 ? -21.661 47.997 -7.321 1.00 49.15 ? 135 ARG A NE 1 ATOM 1026 C CZ . ARG A 1 135 ? -20.827 48.086 -8.352 1.00 51.17 ? 135 ARG A CZ 1 ATOM 1027 N NH1 . ARG A 1 135 ? -21.254 47.839 -9.612 1.00 51.95 ? 135 ARG A NH1 1 ATOM 1028 N NH2 . ARG A 1 135 ? -19.562 48.423 -8.107 1.00 52.41 ? 135 ARG A NH2 1 ATOM 1029 N N . GLN A 1 136 ? -23.798 44.311 -3.615 1.00 28.39 ? 136 GLN A N 1 ATOM 1030 C CA . GLN A 1 136 ? -23.312 44.466 -2.231 1.00 29.58 ? 136 GLN A CA 1 ATOM 1031 C C . GLN A 1 136 ? -24.333 43.881 -1.275 1.00 28.51 ? 136 GLN A C 1 ATOM 1032 O O . GLN A 1 136 ? -25.212 44.584 -0.807 1.00 30.69 ? 136 GLN A O 1 ATOM 1033 C CB . GLN A 1 136 ? -23.004 45.939 -1.865 1.00 29.55 ? 136 GLN A CB 1 ATOM 1034 C CG . GLN A 1 136 ? -22.534 46.884 -2.996 1.00 33.72 ? 136 GLN A CG 1 ATOM 1035 C CD . GLN A 1 136 ? -21.071 46.678 -3.420 1.00 40.40 ? 136 GLN A CD 1 ATOM 1036 O OE1 . GLN A 1 136 ? -20.177 46.491 -2.578 1.00 41.90 ? 136 GLN A OE1 1 ATOM 1037 N NE2 . GLN A 1 136 ? -20.821 46.721 -4.739 1.00 40.24 ? 136 GLN A NE2 1 ATOM 1038 N N . PRO A 1 137 ? -24.264 42.579 -1.012 1.00 27.48 ? 137 PRO A N 1 ATOM 1039 C CA . PRO A 1 137 ? -23.311 41.575 -1.443 1.00 25.88 ? 137 PRO A CA 1 ATOM 1040 C C . PRO A 1 137 ? -23.666 40.980 -2.821 1.00 24.93 ? 137 PRO A C 1 ATOM 1041 O O . PRO A 1 137 ? -24.774 41.184 -3.332 1.00 22.83 ? 137 PRO A O 1 ATOM 1042 C CB . PRO A 1 137 ? -23.442 40.517 -0.346 1.00 26.69 ? 137 PRO A CB 1 ATOM 1043 C CG . PRO A 1 137 ? -24.895 40.607 0.083 1.00 27.05 ? 137 PRO A CG 1 ATOM 1044 C CD . PRO A 1 137 ? -25.349 41.999 -0.192 1.00 27.56 ? 137 PRO A CD 1 ATOM 1045 N N . PHE A 1 138 ? -22.712 40.281 -3.430 1.00 23.22 ? 138 PHE A N 1 ATOM 1046 C CA . PHE A 1 138 ? -22.936 39.695 -4.746 1.00 21.92 ? 138 PHE A CA 1 ATOM 1047 C C . PHE A 1 138 ? -24.081 38.701 -4.708 1.00 21.43 ? 138 PHE A C 1 ATOM 1048 O O . PHE A 1 138 ? -24.112 37.793 -3.866 1.00 20.83 ? 138 PHE A O 1 ATOM 1049 C CB . PHE A 1 138 ? -21.694 38.937 -5.228 1.00 21.25 ? 138 PHE A CB 1 ATOM 1050 C CG . PHE A 1 138 ? -21.952 38.065 -6.438 1.00 21.67 ? 138 PHE A CG 1 ATOM 1051 C CD1 . PHE A 1 138 ? -22.053 36.671 -6.315 1.00 20.43 ? 138 PHE A CD1 1 ATOM 1052 C CD2 . PHE A 1 138 ? -22.129 38.641 -7.695 1.00 20.62 ? 138 PHE A CD2 1 ATOM 1053 C CE1 . PHE A 1 138 ? -22.315 35.873 -7.441 1.00 22.49 ? 138 PHE A CE1 1 ATOM 1054 C CE2 . PHE A 1 138 ? -22.381 37.831 -8.831 1.00 21.96 ? 138 PHE A CE2 1 ATOM 1055 C CZ . PHE A 1 138 ? -22.473 36.457 -8.699 1.00 20.42 ? 138 PHE A CZ 1 ATOM 1056 N N . SER A 1 139 ? -25.010 38.845 -5.642 1.00 20.88 ? 139 SER A N 1 ATOM 1057 C CA . SER A 1 139 ? -25.855 37.719 -5.971 1.00 20.45 ? 139 SER A CA 1 ATOM 1058 C C . SER A 1 139 ? -26.265 37.758 -7.433 1.00 19.48 ? 139 SER A C 1 ATOM 1059 O O . SER A 1 139 ? -26.078 38.775 -8.119 1.00 19.05 ? 139 SER A O 1 ATOM 1060 C CB . SER A 1 139 ? -27.041 37.621 -5.035 1.00 20.47 ? 139 SER A CB 1 ATOM 1061 O OG . SER A 1 139 ? -27.904 38.691 -5.267 1.00 22.68 ? 139 SER A OG 1 ATOM 1062 N N . ILE A 1 140 ? -26.724 36.615 -7.932 1.00 17.98 ? 140 ILE A N 1 ATOM 1063 C CA . ILE A 1 140 ? -27.153 36.500 -9.314 1.00 18.84 ? 140 ILE A CA 1 ATOM 1064 C C . ILE A 1 140 ? -28.526 35.868 -9.309 1.00 18.40 ? 140 ILE A C 1 ATOM 1065 O O . ILE A 1 140 ? -28.807 34.932 -8.558 1.00 18.83 ? 140 ILE A O 1 ATOM 1066 C CB . ILE A 1 140 ? -26.171 35.688 -10.194 1.00 18.88 ? 140 ILE A CB 1 ATOM 1067 C CG1 . ILE A 1 140 ? -26.654 35.603 -11.666 1.00 19.59 ? 140 ILE A CG1 1 ATOM 1068 C CG2 . ILE A 1 140 ? -25.885 34.257 -9.600 1.00 18.43 ? 140 ILE A CG2 1 ATOM 1069 C CD1 . ILE A 1 140 ? -25.495 35.111 -12.681 1.00 19.55 ? 140 ILE A CD1 1 ATOM 1070 N N . LYS A 1 141 ? -29.373 36.386 -10.160 1.00 19.37 ? 141 LYS A N 1 ATOM 1071 C CA . LYS A 1 141 ? -30.746 35.952 -10.218 1.00 19.87 ? 141 LYS A CA 1 ATOM 1072 C C . LYS A 1 141 ? -31.118 35.769 -11.689 1.00 20.08 ? 141 LYS A C 1 ATOM 1073 O O . LYS A 1 141 ? -30.704 36.548 -12.550 1.00 20.93 ? 141 LYS A O 1 ATOM 1074 C CB . LYS A 1 141 ? -31.586 37.057 -9.581 1.00 21.94 ? 141 LYS A CB 1 ATOM 1075 C CG . LYS A 1 141 ? -33.065 36.819 -9.578 1.00 27.43 ? 141 LYS A CG 1 ATOM 1076 C CD . LYS A 1 141 ? -33.832 38.116 -9.243 1.00 36.06 ? 141 LYS A CD 1 ATOM 1077 C CE . LYS A 1 141 ? -33.670 38.551 -7.805 1.00 40.62 ? 141 LYS A CE 1 ATOM 1078 N NZ . LYS A 1 141 ? -34.541 39.770 -7.599 1.00 44.33 ? 141 LYS A NZ 1 ATOM 1079 N N . VAL A 1 142 ? -31.865 34.716 -11.998 1.00 19.10 ? 142 VAL A N 1 ATOM 1080 C CA . VAL A 1 142 ? -32.351 34.497 -13.337 1.00 18.38 ? 142 VAL A CA 1 ATOM 1081 C C . VAL A 1 142 ? -33.864 34.357 -13.199 1.00 18.24 ? 142 VAL A C 1 ATOM 1082 O O . VAL A 1 142 ? -34.343 33.560 -12.403 1.00 16.66 ? 142 VAL A O 1 ATOM 1083 C CB . VAL A 1 142 ? -31.795 33.225 -13.955 1.00 19.25 ? 142 VAL A CB 1 ATOM 1084 C CG1 . VAL A 1 142 ? -32.381 33.020 -15.333 1.00 17.94 ? 142 VAL A CG1 1 ATOM 1085 C CG2 . VAL A 1 142 ? -30.257 33.262 -14.063 1.00 19.33 ? 142 VAL A CG2 1 ATOM 1086 N N . THR A 1 143 ? -34.588 35.187 -13.936 1.00 18.49 ? 143 THR A N 1 ATOM 1087 C CA . THR A 1 143 ? -36.031 35.239 -13.850 1.00 20.04 ? 143 THR A CA 1 ATOM 1088 C C . THR A 1 143 ? -36.582 34.934 -15.219 1.00 19.68 ? 143 THR A C 1 ATOM 1089 O O . THR A 1 143 ? -35.959 35.212 -16.236 1.00 20.53 ? 143 THR A O 1 ATOM 1090 C CB . THR A 1 143 ? -36.506 36.638 -13.469 1.00 19.91 ? 143 THR A CB 1 ATOM 1091 O OG1 . THR A 1 143 ? -35.991 37.552 -14.450 1.00 25.71 ? 143 THR A OG1 1 ATOM 1092 C CG2 . THR A 1 143 ? -35.962 37.020 -12.114 1.00 19.60 ? 143 THR A CG2 1 ATOM 1093 N N . ARG A 1 144 ? -37.762 34.360 -15.230 1.00 18.99 ? 144 ARG A N 1 ATOM 1094 C CA . ARG A 1 144 ? -38.442 34.078 -16.472 1.00 19.36 ? 144 ARG A CA 1 ATOM 1095 C C . ARG A 1 144 ? -39.112 35.391 -16.905 1.00 19.07 ? 144 ARG A C 1 ATOM 1096 O O . ARG A 1 144 ? -39.845 36.013 -16.113 1.00 18.64 ? 144 ARG A O 1 ATOM 1097 C CB . ARG A 1 144 ? -39.484 33.000 -16.211 1.00 18.11 ? 144 ARG A CB 1 ATOM 1098 C CG . ARG A 1 144 ? -40.344 32.665 -17.419 1.00 18.29 ? 144 ARG A CG 1 ATOM 1099 C CD . ARG A 1 144 ? -41.299 31.536 -17.076 1.00 16.17 ? 144 ARG A CD 1 ATOM 1100 N NE . ARG A 1 144 ? -40.648 30.230 -16.922 1.00 17.14 ? 144 ARG A NE 1 ATOM 1101 C CZ . ARG A 1 144 ? -40.217 29.472 -17.939 1.00 14.86 ? 144 ARG A CZ 1 ATOM 1102 N NH1 . ARG A 1 144 ? -40.327 29.880 -19.203 1.00 18.13 ? 144 ARG A NH1 1 ATOM 1103 N NH2 . ARG A 1 144 ? -39.668 28.302 -17.687 1.00 13.74 ? 144 ARG A NH2 1 ATOM 1104 N N . ARG A 1 145 ? -38.853 35.821 -18.132 1.00 20.07 ? 145 ARG A N 1 ATOM 1105 C CA . ARG A 1 145 ? -39.343 37.129 -18.596 1.00 23.11 ? 145 ARG A CA 1 ATOM 1106 C C . ARG A 1 145 ? -40.873 37.192 -18.634 1.00 23.20 ? 145 ARG A C 1 ATOM 1107 O O . ARG A 1 145 ? -41.493 38.210 -18.250 1.00 22.14 ? 145 ARG A O 1 ATOM 1108 C CB . ARG A 1 145 ? -38.778 37.460 -19.969 1.00 23.13 ? 145 ARG A CB 1 ATOM 1109 C CG . ARG A 1 145 ? -37.395 38.115 -19.931 1.00 28.35 ? 145 ARG A CG 1 ATOM 1110 C CD . ARG A 1 145 ? -37.047 38.919 -21.207 1.00 28.81 ? 145 ARG A CD 1 ATOM 1111 N NE . ARG A 1 145 ? -38.234 39.226 -22.004 1.00 41.29 ? 145 ARG A NE 1 ATOM 1112 C CZ . ARG A 1 145 ? -38.227 39.587 -23.291 1.00 43.94 ? 145 ARG A CZ 1 ATOM 1113 N NH1 . ARG A 1 145 ? -37.084 39.699 -23.966 1.00 45.86 ? 145 ARG A NH1 1 ATOM 1114 N NH2 . ARG A 1 145 ? -39.380 39.829 -23.912 1.00 46.11 ? 145 ARG A NH2 1 ATOM 1115 N N . SER A 1 146 ? -41.493 36.107 -19.083 1.00 22.61 ? 146 SER A N 1 ATOM 1116 C CA . SER A 1 146 ? -42.952 36.151 -19.289 1.00 22.98 ? 146 SER A CA 1 ATOM 1117 C C . SER A 1 146 ? -43.741 36.449 -18.003 1.00 23.50 ? 146 SER A C 1 ATOM 1118 O O . SER A 1 146 ? -44.666 37.260 -18.014 1.00 24.76 ? 146 SER A O 1 ATOM 1119 C CB . SER A 1 146 ? -43.440 34.864 -19.943 1.00 22.27 ? 146 SER A CB 1 ATOM 1120 O OG . SER A 1 146 ? -43.378 33.795 -19.016 1.00 22.42 ? 146 SER A OG 1 ATOM 1121 N N . ASN A 1 147 ? -43.385 35.822 -16.885 1.00 23.55 ? 147 ASN A N 1 ATOM 1122 C CA . ASN A 1 147 ? -44.154 36.022 -15.645 1.00 23.24 ? 147 ASN A CA 1 ATOM 1123 C C . ASN A 1 147 ? -43.314 36.571 -14.483 1.00 23.02 ? 147 ASN A C 1 ATOM 1124 O O . ASN A 1 147 ? -43.786 36.671 -13.357 1.00 23.93 ? 147 ASN A O 1 ATOM 1125 C CB . ASN A 1 147 ? -44.861 34.727 -15.231 1.00 23.47 ? 147 ASN A CB 1 ATOM 1126 C CG . ASN A 1 147 ? -43.887 33.588 -14.985 1.00 23.49 ? 147 ASN A CG 1 ATOM 1127 O OD1 . ASN A 1 147 ? -42.662 33.755 -15.090 1.00 20.68 ? 147 ASN A OD1 1 ATOM 1128 N ND2 . ASN A 1 147 ? -44.427 32.434 -14.636 1.00 21.25 ? 147 ASN A ND2 1 ATOM 1129 N N . ASN A 1 148 ? -42.080 36.944 -14.785 1.00 21.89 ? 148 ASN A N 1 ATOM 1130 C CA . ASN A 1 148 ? -41.100 37.381 -13.796 1.00 22.13 ? 148 ASN A CA 1 ATOM 1131 C C . ASN A 1 148 ? -40.878 36.398 -12.656 1.00 20.89 ? 148 ASN A C 1 ATOM 1132 O O . ASN A 1 148 ? -40.521 36.805 -11.544 1.00 21.53 ? 148 ASN A O 1 ATOM 1133 C CB . ASN A 1 148 ? -41.415 38.809 -13.288 1.00 23.43 ? 148 ASN A CB 1 ATOM 1134 C CG . ASN A 1 148 ? -41.105 39.887 -14.341 1.00 26.11 ? 148 ASN A CG 1 ATOM 1135 O OD1 . ASN A 1 148 ? -41.770 40.911 -14.385 1.00 32.99 ? 148 ASN A OD1 1 ATOM 1136 N ND2 . ASN A 1 148 ? -40.088 39.658 -15.178 1.00 22.67 ? 148 ASN A ND2 1 ATOM 1137 N N . ARG A 1 149 ? -41.044 35.111 -12.929 1.00 19.09 ? 149 ARG A N 1 ATOM 1138 C CA . ARG A 1 149 ? -40.879 34.101 -11.858 1.00 18.97 ? 149 ARG A CA 1 ATOM 1139 C C . ARG A 1 149 ? -39.384 34.011 -11.622 1.00 18.45 ? 149 ARG A C 1 ATOM 1140 O O . ARG A 1 149 ? -38.626 33.871 -12.573 1.00 18.89 ? 149 ARG A O 1 ATOM 1141 C CB . ARG A 1 149 ? -41.408 32.758 -12.295 1.00 18.84 ? 149 ARG A CB 1 ATOM 1142 C CG . ARG A 1 149 ? -41.048 31.597 -11.358 1.00 23.39 ? 149 ARG A CG 1 ATOM 1143 C CD . ARG A 1 149 ? -42.154 31.359 -10.404 1.00 29.52 ? 149 ARG A CD 1 ATOM 1144 N NE . ARG A 1 149 ? -43.329 30.863 -11.125 1.00 33.34 ? 149 ARG A NE 1 ATOM 1145 C CZ . ARG A 1 149 ? -44.531 30.735 -10.575 1.00 39.94 ? 149 ARG A CZ 1 ATOM 1146 N NH1 . ARG A 1 149 ? -44.726 31.076 -9.290 1.00 40.56 ? 149 ARG A NH1 1 ATOM 1147 N NH2 . ARG A 1 149 ? -45.544 30.275 -11.306 1.00 38.65 ? 149 ARG A NH2 1 ATOM 1148 N N . VAL A 1 150 ? -38.965 34.128 -10.374 1.00 18.50 ? 150 VAL A N 1 ATOM 1149 C CA . VAL A 1 150 ? -37.528 34.000 -10.072 1.00 18.68 ? 150 VAL A CA 1 ATOM 1150 C C . VAL A 1 150 ? -37.184 32.517 -10.093 1.00 17.83 ? 150 VAL A C 1 ATOM 1151 O O . VAL A 1 150 ? -37.795 31.710 -9.357 1.00 17.97 ? 150 VAL A O 1 ATOM 1152 C CB . VAL A 1 150 ? -37.157 34.629 -8.703 1.00 19.66 ? 150 VAL A CB 1 ATOM 1153 C CG1 . VAL A 1 150 ? -35.682 34.386 -8.393 1.00 20.18 ? 150 VAL A CG1 1 ATOM 1154 C CG2 . VAL A 1 150 ? -37.447 36.138 -8.722 1.00 21.30 ? 150 VAL A CG2 1 ATOM 1155 N N . LEU A 1 151 ? -36.209 32.157 -10.928 1.00 16.73 ? 151 LEU A N 1 ATOM 1156 C CA . LEU A 1 151 ? -35.871 30.752 -11.124 1.00 16.94 ? 151 LEU A CA 1 ATOM 1157 C C . LEU A 1 151 ? -34.619 30.399 -10.322 1.00 17.99 ? 151 LEU A C 1 ATOM 1158 O O . LEU A 1 151 ? -34.627 29.517 -9.478 1.00 19.34 ? 151 LEU A O 1 ATOM 1159 C CB . LEU A 1 151 ? -35.650 30.441 -12.613 1.00 16.39 ? 151 LEU A CB 1 ATOM 1160 C CG . LEU A 1 151 ? -36.860 30.792 -13.512 1.00 15.46 ? 151 LEU A CG 1 ATOM 1161 C CD1 . LEU A 1 151 ? -36.525 30.332 -14.915 1.00 15.00 ? 151 LEU A CD1 1 ATOM 1162 C CD2 . LEU A 1 151 ? -38.091 30.151 -12.997 1.00 18.31 ? 151 LEU A CD2 1 ATOM 1163 N N . PHE A 1 152 ? -33.553 31.104 -10.638 1.00 18.18 ? 152 PHE A N 1 ATOM 1164 C CA . PHE A 1 152 ? -32.273 30.964 -9.941 1.00 19.01 ? 152 PHE A CA 1 ATOM 1165 C C . PHE A 1 152 ? -32.085 32.278 -9.152 1.00 19.30 ? 152 PHE A C 1 ATOM 1166 O O . PHE A 1 152 ? -32.346 33.390 -9.671 1.00 20.20 ? 152 PHE A O 1 ATOM 1167 C CB . PHE A 1 152 ? -31.182 30.836 -10.978 1.00 18.77 ? 152 PHE A CB 1 ATOM 1168 C CG . PHE A 1 152 ? -29.872 30.340 -10.424 1.00 20.50 ? 152 PHE A CG 1 ATOM 1169 C CD1 . PHE A 1 152 ? -29.509 28.996 -10.554 1.00 20.40 ? 152 PHE A CD1 1 ATOM 1170 C CD2 . PHE A 1 152 ? -29.014 31.211 -9.772 1.00 20.79 ? 152 PHE A CD2 1 ATOM 1171 C CE1 . PHE A 1 152 ? -28.262 28.524 -10.069 1.00 23.17 ? 152 PHE A CE1 1 ATOM 1172 C CE2 . PHE A 1 152 ? -27.762 30.749 -9.270 1.00 20.42 ? 152 PHE A CE2 1 ATOM 1173 C CZ . PHE A 1 152 ? -27.407 29.413 -9.404 1.00 21.08 ? 152 PHE A CZ 1 ATOM 1174 N N . ASP A 1 153 ? -31.704 32.169 -7.893 1.00 19.18 ? 153 ASP A N 1 ATOM 1175 C CA . ASP A 1 153 ? -31.522 33.352 -7.046 1.00 19.69 ? 153 ASP A CA 1 ATOM 1176 C C . ASP A 1 153 ? -30.532 32.933 -5.991 1.00 18.81 ? 153 ASP A C 1 ATOM 1177 O O . ASP A 1 153 ? -30.905 32.278 -5.016 1.00 19.22 ? 153 ASP A O 1 ATOM 1178 C CB . ASP A 1 153 ? -32.834 33.748 -6.361 1.00 19.77 ? 153 ASP A CB 1 ATOM 1179 C CG . ASP A 1 153 ? -32.688 34.971 -5.451 1.00 22.83 ? 153 ASP A CG 1 ATOM 1180 O OD1 . ASP A 1 153 ? -31.588 35.609 -5.396 1.00 25.21 ? 153 ASP A OD1 1 ATOM 1181 O OD2 . ASP A 1 153 ? -33.694 35.297 -4.769 1.00 27.40 ? 153 ASP A OD2 1 ATOM 1182 N N . SER A 1 154 ? -29.273 33.276 -6.177 1.00 19.07 ? 154 SER A N 1 ATOM 1183 C CA . SER A 1 154 ? -28.258 32.936 -5.181 1.00 18.51 ? 154 SER A CA 1 ATOM 1184 C C . SER A 1 154 ? -28.286 33.777 -3.886 1.00 19.34 ? 154 SER A C 1 ATOM 1185 O O . SER A 1 154 ? -27.507 33.500 -2.950 1.00 19.09 ? 154 SER A O 1 ATOM 1186 C CB . SER A 1 154 ? -26.874 33.038 -5.811 1.00 18.88 ? 154 SER A CB 1 ATOM 1187 O OG . SER A 1 154 ? -26.481 34.415 -5.911 1.00 20.73 ? 154 SER A OG 1 ATOM 1188 N N . SER A 1 155 ? -29.144 34.803 -3.818 1.00 19.15 ? 155 SER A N 1 ATOM 1189 C CA . SER A 1 155 ? -29.116 35.733 -2.686 1.00 19.71 ? 155 SER A CA 1 ATOM 1190 C C . SER A 1 155 ? -29.487 35.084 -1.349 1.00 19.28 ? 155 SER A C 1 ATOM 1191 O O . SER A 1 155 ? -29.292 35.691 -0.308 1.00 18.49 ? 155 SER A O 1 ATOM 1192 C CB . SER A 1 155 ? -30.009 36.964 -2.952 1.00 20.70 ? 155 SER A CB 1 ATOM 1193 O OG . SER A 1 155 ? -31.370 36.561 -2.934 1.00 21.77 ? 155 SER A OG 1 ATOM 1194 N N . ILE A 1 156 ? -29.994 33.851 -1.374 1.00 18.57 ? 156 ILE A N 1 ATOM 1195 C CA . ILE A 1 156 ? -30.313 33.136 -0.122 1.00 18.84 ? 156 ILE A CA 1 ATOM 1196 C C . ILE A 1 156 ? -29.022 32.840 0.685 1.00 18.46 ? 156 ILE A C 1 ATOM 1197 O O . ILE A 1 156 ? -29.044 32.710 1.893 1.00 19.97 ? 156 ILE A O 1 ATOM 1198 C CB . ILE A 1 156 ? -31.122 31.843 -0.390 1.00 19.09 ? 156 ILE A CB 1 ATOM 1199 C CG1 . ILE A 1 156 ? -31.717 31.296 0.920 1.00 18.80 ? 156 ILE A CG1 1 ATOM 1200 C CG2 . ILE A 1 156 ? -30.319 30.804 -1.216 1.00 21.12 ? 156 ILE A CG2 1 ATOM 1201 C CD1 . ILE A 1 156 ? -32.658 30.091 0.748 1.00 18.35 ? 156 ILE A CD1 1 ATOM 1202 N N . GLY A 1 157 ? -27.892 32.758 0.017 1.00 17.53 ? 157 GLY A N 1 ATOM 1203 C CA . GLY A 1 157 ? -26.706 32.374 0.733 1.00 17.00 ? 157 GLY A CA 1 ATOM 1204 C C . GLY A 1 157 ? -25.507 33.045 0.120 1.00 16.89 ? 157 GLY A C 1 ATOM 1205 O O . GLY A 1 157 ? -25.595 33.815 -0.843 1.00 16.26 ? 157 GLY A O 1 ATOM 1206 N N . PRO A 1 158 ? -24.364 32.804 0.726 1.00 16.87 ? 158 PRO A N 1 ATOM 1207 C CA . PRO A 1 158 ? -23.099 33.352 0.248 1.00 17.31 ? 158 PRO A CA 1 ATOM 1208 C C . PRO A 1 158 ? -22.559 32.684 -1.032 1.00 17.47 ? 158 PRO A C 1 ATOM 1209 O O . PRO A 1 158 ? -22.998 31.608 -1.412 1.00 18.40 ? 158 PRO A O 1 ATOM 1210 C CB . PRO A 1 158 ? -22.163 33.062 1.428 1.00 17.77 ? 158 PRO A CB 1 ATOM 1211 C CG . PRO A 1 158 ? -22.642 31.794 1.994 1.00 16.93 ? 158 PRO A CG 1 ATOM 1212 C CD . PRO A 1 158 ? -24.207 31.981 1.934 1.00 16.82 ? 158 PRO A CD 1 ATOM 1213 N N . LEU A 1 159 ? -21.610 33.329 -1.705 1.00 17.47 ? 159 LEU A N 1 ATOM 1214 C CA . LEU A 1 159 ? -20.758 32.618 -2.622 1.00 17.08 ? 159 LEU A CA 1 ATOM 1215 C C . LEU A 1 159 ? -19.544 32.313 -1.785 1.00 18.47 ? 159 LEU A C 1 ATOM 1216 O O . LEU A 1 159 ? -19.010 33.249 -1.163 1.00 17.96 ? 159 LEU A O 1 ATOM 1217 C CB . LEU A 1 159 ? -20.334 33.511 -3.797 1.00 17.09 ? 159 LEU A CB 1 ATOM 1218 C CG . LEU A 1 159 ? -19.065 33.092 -4.576 1.00 15.79 ? 159 LEU A CG 1 ATOM 1219 C CD1 . LEU A 1 159 ? -19.136 31.675 -5.226 1.00 14.23 ? 159 LEU A CD1 1 ATOM 1220 C CD2 . LEU A 1 159 ? -18.721 34.181 -5.621 1.00 17.22 ? 159 LEU A CD2 1 ATOM 1221 N N . LEU A 1 160 ? -19.111 31.038 -1.753 1.00 18.34 ? 160 LEU A N 1 ATOM 1222 C CA . LEU A 1 160 ? -17.853 30.661 -1.074 1.00 18.59 ? 160 LEU A CA 1 ATOM 1223 C C . LEU A 1 160 ? -16.965 30.134 -2.141 1.00 19.61 ? 160 LEU A C 1 ATOM 1224 O O . LEU A 1 160 ? -17.425 29.400 -3.005 1.00 17.69 ? 160 LEU A O 1 ATOM 1225 C CB . LEU A 1 160 ? -18.090 29.605 0.018 1.00 18.54 ? 160 LEU A CB 1 ATOM 1226 C CG . LEU A 1 160 ? -19.172 30.137 0.983 1.00 18.19 ? 160 LEU A CG 1 ATOM 1227 C CD1 . LEU A 1 160 ? -19.750 29.061 1.859 1.00 22.80 ? 160 LEU A CD1 1 ATOM 1228 C CD2 . LEU A 1 160 ? -18.678 31.261 1.860 1.00 19.34 ? 160 LEU A CD2 1 ATOM 1229 N N . PHE A 1 161 ? -15.684 30.524 -2.115 1.00 19.47 ? 161 PHE A N 1 ATOM 1230 C CA . PHE A 1 161 ? -14.785 30.140 -3.173 1.00 20.49 ? 161 PHE A CA 1 ATOM 1231 C C . PHE A 1 161 ? -13.360 30.036 -2.619 1.00 21.37 ? 161 PHE A C 1 ATOM 1232 O O . PHE A 1 161 ? -12.575 30.986 -2.740 1.00 23.14 ? 161 PHE A O 1 ATOM 1233 C CB . PHE A 1 161 ? -14.835 31.186 -4.292 1.00 20.94 ? 161 PHE A CB 1 ATOM 1234 C CG . PHE A 1 161 ? -14.372 30.690 -5.647 1.00 23.05 ? 161 PHE A CG 1 ATOM 1235 C CD1 . PHE A 1 161 ? -15.189 30.834 -6.772 1.00 27.55 ? 161 PHE A CD1 1 ATOM 1236 C CD2 . PHE A 1 161 ? -13.126 30.089 -5.810 1.00 26.89 ? 161 PHE A CD2 1 ATOM 1237 C CE1 . PHE A 1 161 ? -14.762 30.371 -8.019 1.00 27.32 ? 161 PHE A CE1 1 ATOM 1238 C CE2 . PHE A 1 161 ? -12.675 29.640 -7.055 1.00 26.71 ? 161 PHE A CE2 1 ATOM 1239 C CZ . PHE A 1 161 ? -13.476 29.789 -8.158 1.00 27.13 ? 161 PHE A CZ 1 ATOM 1240 N N . ALA A 1 162 ? -13.042 28.901 -2.005 1.00 21.71 ? 162 ALA A N 1 ATOM 1241 C CA . ALA A 1 162 ? -11.671 28.583 -1.621 1.00 21.07 ? 162 ALA A CA 1 ATOM 1242 C C . ALA A 1 162 ? -11.169 27.526 -2.576 1.00 22.13 ? 162 ALA A C 1 ATOM 1243 O O . ALA A 1 162 ? -11.936 26.912 -3.313 1.00 21.03 ? 162 ALA A O 1 ATOM 1244 C CB . ALA A 1 162 ? -11.616 28.098 -0.198 1.00 21.87 ? 162 ALA A CB 1 ATOM 1245 N N . ASP A 1 163 ? -9.867 27.285 -2.564 1.00 21.28 ? 163 ASP A N 1 ATOM 1246 C CA . ASP A 1 163 ? -9.281 26.358 -3.503 1.00 22.37 ? 163 ASP A CA 1 ATOM 1247 C C . ASP A 1 163 ? -9.953 24.976 -3.441 1.00 21.31 ? 163 ASP A C 1 ATOM 1248 O O . ASP A 1 163 ? -10.131 24.314 -4.481 1.00 20.90 ? 163 ASP A O 1 ATOM 1249 C CB . ASP A 1 163 ? -7.772 26.297 -3.241 1.00 23.62 ? 163 ASP A CB 1 ATOM 1250 C CG . ASP A 1 163 ? -7.017 25.447 -4.247 1.00 27.79 ? 163 ASP A CG 1 ATOM 1251 O OD1 . ASP A 1 163 ? -7.208 25.578 -5.481 1.00 32.76 ? 163 ASP A OD1 1 ATOM 1252 O OD2 . ASP A 1 163 ? -6.207 24.629 -3.783 1.00 30.21 ? 163 ASP A OD2 1 ATOM 1253 N N . GLN A 1 164 ? -10.340 24.548 -2.234 1.00 19.26 ? 164 GLN A N 1 ATOM 1254 C CA . GLN A 1 164 ? -10.900 23.215 -2.073 1.00 18.23 ? 164 GLN A CA 1 ATOM 1255 C C . GLN A 1 164 ? -12.234 23.292 -1.396 1.00 18.12 ? 164 GLN A C 1 ATOM 1256 O O . GLN A 1 164 ? -12.647 22.353 -0.706 1.00 17.83 ? 164 GLN A O 1 ATOM 1257 C CB . GLN A 1 164 ? -9.967 22.306 -1.276 1.00 18.42 ? 164 GLN A CB 1 ATOM 1258 C CG . GLN A 1 164 ? -8.618 22.143 -1.980 1.00 17.59 ? 164 GLN A CG 1 ATOM 1259 C CD . GLN A 1 164 ? -7.764 21.099 -1.316 1.00 20.67 ? 164 GLN A CD 1 ATOM 1260 O OE1 . GLN A 1 164 ? -8.017 19.889 -1.434 1.00 21.02 ? 164 GLN A OE1 1 ATOM 1261 N NE2 . GLN A 1 164 ? -6.752 21.544 -0.615 1.00 19.82 ? 164 GLN A NE2 1 ATOM 1262 N N . PHE A 1 165 ? -12.917 24.419 -1.581 1.00 17.72 ? 165 PHE A N 1 ATOM 1263 C CA . PHE A 1 165 ? -14.273 24.543 -1.074 1.00 18.27 ? 165 PHE A CA 1 ATOM 1264 C C . PHE A 1 165 ? -15.016 25.633 -1.809 1.00 17.83 ? 165 PHE A C 1 ATOM 1265 O O . PHE A 1 165 ? -14.723 26.837 -1.627 1.00 17.29 ? 165 PHE A O 1 ATOM 1266 C CB . PHE A 1 165 ? -14.321 24.830 0.418 1.00 19.19 ? 165 PHE A CB 1 ATOM 1267 C CG . PHE A 1 165 ? -15.685 24.674 1.014 1.00 19.99 ? 165 PHE A CG 1 ATOM 1268 C CD1 . PHE A 1 165 ? -16.109 23.438 1.494 1.00 22.83 ? 165 PHE A CD1 1 ATOM 1269 C CD2 . PHE A 1 165 ? -16.548 25.753 1.110 1.00 24.42 ? 165 PHE A CD2 1 ATOM 1270 C CE1 . PHE A 1 165 ? -17.394 23.288 2.074 1.00 24.79 ? 165 PHE A CE1 1 ATOM 1271 C CE2 . PHE A 1 165 ? -17.817 25.612 1.684 1.00 24.68 ? 165 PHE A CE2 1 ATOM 1272 C CZ . PHE A 1 165 ? -18.238 24.390 2.173 1.00 23.90 ? 165 PHE A CZ 1 ATOM 1273 N N . LEU A 1 166 ? -16.009 25.228 -2.612 1.00 16.65 ? 166 LEU A N 1 ATOM 1274 C CA . LEU A 1 166 ? -16.751 26.206 -3.430 1.00 16.63 ? 166 LEU A CA 1 ATOM 1275 C C . LEU A 1 166 ? -18.230 25.926 -3.205 1.00 16.50 ? 166 LEU A C 1 ATOM 1276 O O . LEU A 1 166 ? -18.628 24.779 -3.192 1.00 17.12 ? 166 LEU A O 1 ATOM 1277 C CB . LEU A 1 166 ? -16.413 26.056 -4.909 1.00 16.43 ? 166 LEU A CB 1 ATOM 1278 C CG . LEU A 1 166 ? -14.990 26.335 -5.393 1.00 19.40 ? 166 LEU A CG 1 ATOM 1279 C CD1 . LEU A 1 166 ? -14.120 25.115 -5.195 1.00 20.57 ? 166 LEU A CD1 1 ATOM 1280 C CD2 . LEU A 1 166 ? -15.084 26.694 -6.858 1.00 22.01 ? 166 LEU A CD2 1 ATOM 1281 N N . GLN A 1 167 ? -19.012 26.949 -2.932 1.00 16.10 ? 167 GLN A N 1 ATOM 1282 C CA . GLN A 1 167 ? -20.422 26.731 -2.654 1.00 16.76 ? 167 GLN A CA 1 ATOM 1283 C C . GLN A 1 167 ? -21.269 27.893 -3.226 1.00 16.84 ? 167 GLN A C 1 ATOM 1284 O O . GLN A 1 167 ? -20.888 29.072 -3.140 1.00 16.81 ? 167 GLN A O 1 ATOM 1285 C CB . GLN A 1 167 ? -20.657 26.628 -1.141 1.00 17.01 ? 167 GLN A CB 1 ATOM 1286 C CG . GLN A 1 167 ? -22.125 26.541 -0.753 1.00 17.63 ? 167 GLN A CG 1 ATOM 1287 C CD . GLN A 1 167 ? -22.330 26.330 0.735 1.00 18.40 ? 167 GLN A CD 1 ATOM 1288 O OE1 . GLN A 1 167 ? -23.151 27.025 1.381 1.00 19.77 ? 167 GLN A OE1 1 ATOM 1289 N NE2 . GLN A 1 167 ? -21.599 25.378 1.296 1.00 13.66 ? 167 GLN A NE2 1 ATOM 1290 N N . LEU A 1 168 ? -22.400 27.549 -3.825 1.00 17.36 ? 168 LEU A N 1 ATOM 1291 C CA . LEU A 1 168 ? -23.391 28.557 -4.173 1.00 16.94 ? 168 LEU A CA 1 ATOM 1292 C C . LEU A 1 168 ? -24.757 27.918 -3.975 1.00 17.49 ? 168 LEU A C 1 ATOM 1293 O O . LEU A 1 168 ? -24.929 26.705 -4.155 1.00 16.30 ? 168 LEU A O 1 ATOM 1294 C CB . LEU A 1 168 ? -23.202 29.001 -5.626 1.00 17.92 ? 168 LEU A CB 1 ATOM 1295 C CG . LEU A 1 168 ? -23.952 30.303 -6.014 1.00 18.67 ? 168 LEU A CG 1 ATOM 1296 C CD1 . LEU A 1 168 ? -23.267 31.565 -5.427 1.00 18.44 ? 168 LEU A CD1 1 ATOM 1297 C CD2 . LEU A 1 168 ? -24.104 30.391 -7.532 1.00 21.52 ? 168 LEU A CD2 1 ATOM 1298 N N . SER A 1 169 ? -25.720 28.727 -3.564 1.00 17.83 ? 169 SER A N 1 ATOM 1299 C CA . SER A 1 169 ? -27.054 28.238 -3.333 1.00 17.71 ? 169 SER A CA 1 ATOM 1300 C C . SER A 1 169 ? -27.979 28.933 -4.314 1.00 18.06 ? 169 SER A C 1 ATOM 1301 O O . SER A 1 169 ? -27.620 29.948 -4.891 1.00 18.48 ? 169 SER A O 1 ATOM 1302 C CB . SER A 1 169 ? -27.501 28.579 -1.916 1.00 17.50 ? 169 SER A CB 1 ATOM 1303 O OG . SER A 1 169 ? -26.548 28.126 -0.981 1.00 17.78 ? 169 SER A OG 1 ATOM 1304 N N . THR A 1 170 ? -29.170 28.376 -4.504 1.00 17.82 ? 170 THR A N 1 ATOM 1305 C CA . THR A 1 170 ? -30.207 29.083 -5.214 1.00 18.68 ? 170 THR A CA 1 ATOM 1306 C C . THR A 1 170 ? -31.558 28.770 -4.559 1.00 17.75 ? 170 THR A C 1 ATOM 1307 O O . THR A 1 170 ? -31.833 27.626 -4.190 1.00 17.26 ? 170 THR A O 1 ATOM 1308 C CB . THR A 1 170 ? -30.248 28.710 -6.710 1.00 19.66 ? 170 THR A CB 1 ATOM 1309 O OG1 . THR A 1 170 ? -31.399 29.312 -7.324 1.00 21.21 ? 170 THR A OG1 1 ATOM 1310 C CG2 . THR A 1 170 ? -30.328 27.176 -6.920 1.00 20.48 ? 170 THR A CG2 1 ATOM 1311 N N . ARG A 1 171 ? -32.378 29.788 -4.409 1.00 17.66 ? 171 ARG A N 1 ATOM 1312 C CA . ARG A 1 171 ? -33.800 29.559 -4.141 1.00 18.58 ? 171 ARG A CA 1 ATOM 1313 C C . ARG A 1 171 ? -34.401 28.810 -5.316 1.00 18.55 ? 171 ARG A C 1 ATOM 1314 O O . ARG A 1 171 ? -33.856 28.839 -6.443 1.00 19.15 ? 171 ARG A O 1 ATOM 1315 C CB . ARG A 1 171 ? -34.526 30.882 -3.978 1.00 18.93 ? 171 ARG A CB 1 ATOM 1316 C CG . ARG A 1 171 ? -34.098 31.681 -2.803 1.00 21.26 ? 171 ARG A CG 1 ATOM 1317 C CD . ARG A 1 171 ? -34.948 32.956 -2.708 1.00 25.61 ? 171 ARG A CD 1 ATOM 1318 N NE . ARG A 1 171 ? -34.065 34.079 -2.381 1.00 33.07 ? 171 ARG A NE 1 ATOM 1319 C CZ . ARG A 1 171 ? -33.833 34.493 -1.153 1.00 32.68 ? 171 ARG A CZ 1 ATOM 1320 N NH1 . ARG A 1 171 ? -34.468 33.914 -0.140 1.00 34.15 ? 171 ARG A NH1 1 ATOM 1321 N NH2 . ARG A 1 171 ? -33.008 35.506 -0.952 1.00 36.76 ? 171 ARG A NH2 1 ATOM 1322 N N . LEU A 1 172 ? -35.542 28.167 -5.073 1.00 17.77 ? 172 LEU A N 1 ATOM 1323 C CA . LEU A 1 172 ? -36.265 27.480 -6.126 1.00 18.20 ? 172 LEU A CA 1 ATOM 1324 C C . LEU A 1 172 ? -37.691 27.936 -6.062 1.00 18.45 ? 172 LEU A C 1 ATOM 1325 O O . LEU A 1 172 ? -38.148 28.294 -4.995 1.00 17.30 ? 172 LEU A O 1 ATOM 1326 C CB . LEU A 1 172 ? -36.199 25.960 -5.929 1.00 18.68 ? 172 LEU A CB 1 ATOM 1327 C CG . LEU A 1 172 ? -34.825 25.323 -6.136 1.00 19.93 ? 172 LEU A CG 1 ATOM 1328 C CD1 . LEU A 1 172 ? -34.838 23.866 -5.708 1.00 23.32 ? 172 LEU A CD1 1 ATOM 1329 C CD2 . LEU A 1 172 ? -34.318 25.483 -7.571 1.00 21.99 ? 172 LEU A CD2 1 ATOM 1330 N N . PRO A 1 173 ? -38.384 27.971 -7.213 1.00 19.85 ? 173 PRO A N 1 ATOM 1331 C CA . PRO A 1 173 ? -39.776 28.456 -7.254 1.00 20.71 ? 173 PRO A CA 1 ATOM 1332 C C . PRO A 1 173 ? -40.808 27.431 -6.837 1.00 21.61 ? 173 PRO A C 1 ATOM 1333 O O . PRO A 1 173 ? -41.998 27.789 -6.686 1.00 22.36 ? 173 PRO A O 1 ATOM 1334 C CB . PRO A 1 173 ? -39.959 28.856 -8.730 1.00 20.58 ? 173 PRO A CB 1 ATOM 1335 C CG . PRO A 1 173 ? -39.060 27.942 -9.488 1.00 19.80 ? 173 PRO A CG 1 ATOM 1336 C CD . PRO A 1 173 ? -37.883 27.615 -8.554 1.00 20.68 ? 173 PRO A CD 1 ATOM 1337 N N . SER A 1 174 ? -40.401 26.170 -6.663 1.00 21.53 ? 174 SER A N 1 ATOM 1338 C CA . SER A 1 174 ? -41.323 25.108 -6.266 1.00 21.02 ? 174 SER A CA 1 ATOM 1339 C C . SER A 1 174 ? -40.550 23.951 -5.640 1.00 21.27 ? 174 SER A C 1 ATOM 1340 O O . SER A 1 174 ? -39.311 23.887 -5.701 1.00 21.28 ? 174 SER A O 1 ATOM 1341 C CB . SER A 1 174 ? -42.130 24.584 -7.474 1.00 21.33 ? 174 SER A CB 1 ATOM 1342 O OG . SER A 1 174 ? -41.342 23.691 -8.245 1.00 19.52 ? 174 SER A OG 1 ATOM 1343 N N . THR A 1 175 ? -41.288 23.028 -5.051 1.00 20.29 ? 175 THR A N 1 ATOM 1344 C CA . THR A 1 175 ? -40.681 21.807 -4.539 1.00 20.21 ? 175 THR A CA 1 ATOM 1345 C C . THR A 1 175 ? -40.745 20.637 -5.543 1.00 18.97 ? 175 THR A C 1 ATOM 1346 O O . THR A 1 175 ? -40.454 19.489 -5.175 1.00 18.65 ? 175 THR A O 1 ATOM 1347 C CB . THR A 1 175 ? -41.368 21.401 -3.201 1.00 21.52 ? 175 THR A CB 1 ATOM 1348 O OG1 . THR A 1 175 ? -42.785 21.338 -3.438 1.00 22.70 ? 175 THR A OG1 1 ATOM 1349 C CG2 . THR A 1 175 ? -41.076 22.448 -2.126 1.00 22.06 ? 175 THR A CG2 1 ATOM 1350 N N . ASN A 1 176 ? -41.131 20.907 -6.797 1.00 17.00 ? 176 ASN A N 1 ATOM 1351 C CA . ASN A 1 176 ? -41.225 19.837 -7.788 1.00 16.52 ? 176 ASN A CA 1 ATOM 1352 C C . ASN A 1 176 ? -39.864 19.776 -8.423 1.00 15.63 ? 176 ASN A C 1 ATOM 1353 O O . ASN A 1 176 ? -39.671 20.402 -9.429 1.00 15.26 ? 176 ASN A O 1 ATOM 1354 C CB . ASN A 1 176 ? -42.226 20.190 -8.877 1.00 15.80 ? 176 ASN A CB 1 ATOM 1355 C CG . ASN A 1 176 ? -43.607 20.448 -8.322 1.00 21.10 ? 176 ASN A CG 1 ATOM 1356 O OD1 . ASN A 1 176 ? -44.074 19.717 -7.446 1.00 21.65 ? 176 ASN A OD1 1 ATOM 1357 N ND2 . ASN A 1 176 ? -44.251 21.501 -8.799 1.00 21.63 ? 176 ASN A ND2 1 ATOM 1358 N N . VAL A 1 177 ? -38.939 19.069 -7.781 1.00 15.43 ? 177 VAL A N 1 ATOM 1359 C CA . VAL A 1 177 ? -37.515 19.013 -8.164 1.00 14.56 ? 177 VAL A CA 1 ATOM 1360 C C . VAL A 1 177 ? -37.157 17.553 -8.452 1.00 13.70 ? 177 VAL A C 1 ATOM 1361 O O . VAL A 1 177 ? -37.412 16.655 -7.636 1.00 14.30 ? 177 VAL A O 1 ATOM 1362 C CB . VAL A 1 177 ? -36.601 19.551 -7.033 1.00 14.89 ? 177 VAL A CB 1 ATOM 1363 C CG1 . VAL A 1 177 ? -35.137 19.278 -7.387 1.00 15.11 ? 177 VAL A CG1 1 ATOM 1364 C CG2 . VAL A 1 177 ? -36.834 21.057 -6.849 1.00 17.64 ? 177 VAL A CG2 1 ATOM 1365 N N . TYR A 1 178 ? -36.586 17.307 -9.616 1.00 13.94 ? 178 TYR A N 1 ATOM 1366 C CA . TYR A 1 178 ? -36.338 15.944 -10.067 1.00 13.19 ? 178 TYR A CA 1 ATOM 1367 C C . TYR A 1 178 ? -34.917 15.900 -10.581 1.00 13.25 ? 178 TYR A C 1 ATOM 1368 O O . TYR A 1 178 ? -34.540 16.796 -11.320 1.00 13.79 ? 178 TYR A O 1 ATOM 1369 C CB . TYR A 1 178 ? -37.227 15.635 -11.255 1.00 13.11 ? 178 TYR A CB 1 ATOM 1370 C CG . TYR A 1 178 ? -38.679 15.900 -10.903 1.00 12.85 ? 178 TYR A CG 1 ATOM 1371 C CD1 . TYR A 1 178 ? -39.417 14.977 -10.212 1.00 12.94 ? 178 TYR A CD1 1 ATOM 1372 C CD2 . TYR A 1 178 ? -39.254 17.121 -11.228 1.00 13.70 ? 178 TYR A CD2 1 ATOM 1373 C CE1 . TYR A 1 178 ? -40.789 15.264 -9.881 1.00 9.32 ? 178 TYR A CE1 1 ATOM 1374 C CE2 . TYR A 1 178 ? -40.586 17.432 -10.917 1.00 15.09 ? 178 TYR A CE2 1 ATOM 1375 C CZ . TYR A 1 178 ? -41.320 16.523 -10.197 1.00 12.47 ? 178 TYR A CZ 1 ATOM 1376 O OH . TYR A 1 178 ? -42.689 16.806 -9.889 1.00 16.48 ? 178 TYR A OH 1 ATOM 1377 N N . GLY A 1 179 ? -34.171 14.838 -10.298 1.00 14.01 ? 179 GLY A N 1 ATOM 1378 C CA . GLY A 1 179 ? -32.794 14.788 -10.850 1.00 13.07 ? 179 GLY A CA 1 ATOM 1379 C C . GLY A 1 179 ? -31.713 14.553 -9.818 1.00 14.36 ? 179 GLY A C 1 ATOM 1380 O O . GLY A 1 179 ? -31.987 14.083 -8.727 1.00 16.17 ? 179 GLY A O 1 ATOM 1381 N N . LEU A 1 180 ? -30.476 14.861 -10.183 1.00 14.36 ? 180 LEU A N 1 ATOM 1382 C CA . LEU A 1 180 ? -29.296 14.528 -9.375 1.00 14.50 ? 180 LEU A CA 1 ATOM 1383 C C . LEU A 1 180 ? -28.987 13.043 -9.354 1.00 14.92 ? 180 LEU A C 1 ATOM 1384 O O . LEU A 1 180 ? -29.873 12.191 -9.396 1.00 14.95 ? 180 LEU A O 1 ATOM 1385 C CB . LEU A 1 180 ? -29.395 15.044 -7.936 1.00 14.38 ? 180 LEU A CB 1 ATOM 1386 C CG . LEU A 1 180 ? -29.832 16.492 -7.724 1.00 17.83 ? 180 LEU A CG 1 ATOM 1387 C CD1 . LEU A 1 180 ? -30.123 16.697 -6.248 1.00 19.00 ? 180 LEU A CD1 1 ATOM 1388 C CD2 . LEU A 1 180 ? -28.784 17.516 -8.322 1.00 16.79 ? 180 LEU A CD2 1 ATOM 1389 N N . GLY A 1 181 ? -27.706 12.687 -9.291 1.00 12.82 ? 181 GLY A N 1 ATOM 1390 C CA . GLY A 1 181 ? -27.416 11.290 -9.292 1.00 13.36 ? 181 GLY A CA 1 ATOM 1391 C C . GLY A 1 181 ? -25.902 11.127 -9.184 1.00 13.43 ? 181 GLY A C 1 ATOM 1392 O O . GLY A 1 181 ? -25.215 12.111 -9.174 1.00 15.04 ? 181 GLY A O 1 ATOM 1393 N N . GLU A 1 182 ? -25.408 9.899 -9.133 1.00 15.43 ? 182 GLU A N 1 ATOM 1394 C CA . GLU A 1 182 ? -26.257 8.693 -9.108 1.00 14.32 ? 182 GLU A CA 1 ATOM 1395 C C . GLU A 1 182 ? -26.597 8.239 -7.703 1.00 15.15 ? 182 GLU A C 1 ATOM 1396 O O . GLU A 1 182 ? -25.699 8.056 -6.886 1.00 14.00 ? 182 GLU A O 1 ATOM 1397 C CB . GLU A 1 182 ? -25.588 7.538 -9.834 1.00 15.78 ? 182 GLU A CB 1 ATOM 1398 C CG . GLU A 1 182 ? -26.606 6.400 -10.066 1.00 15.07 ? 182 GLU A CG 1 ATOM 1399 C CD . GLU A 1 182 ? -26.040 5.320 -10.951 1.00 20.55 ? 182 GLU A CD 1 ATOM 1400 O OE1 . GLU A 1 182 ? -24.849 5.439 -11.328 1.00 20.58 ? 182 GLU A OE1 1 ATOM 1401 O OE2 . GLU A 1 182 ? -26.780 4.367 -11.255 1.00 21.90 ? 182 GLU A OE2 1 ATOM 1402 N N . HIS A 1 183 ? -27.901 8.065 -7.402 1.00 14.49 ? 183 HIS A N 1 ATOM 1403 C CA . HIS A 1 183 ? -28.301 7.727 -6.042 1.00 15.59 ? 183 HIS A CA 1 ATOM 1404 C C . HIS A 1 183 ? -29.530 6.848 -6.165 1.00 16.24 ? 183 HIS A C 1 ATOM 1405 O O . HIS A 1 183 ? -30.195 6.805 -7.232 1.00 15.63 ? 183 HIS A O 1 ATOM 1406 C CB . HIS A 1 183 ? -28.749 8.956 -5.172 1.00 16.50 ? 183 HIS A CB 1 ATOM 1407 C CG . HIS A 1 183 ? -27.880 10.166 -5.283 1.00 16.77 ? 183 HIS A CG 1 ATOM 1408 N ND1 . HIS A 1 183 ? -26.588 10.210 -4.793 1.00 19.27 ? 183 HIS A ND1 1 ATOM 1409 C CD2 . HIS A 1 183 ? -28.134 11.391 -5.786 1.00 10.71 ? 183 HIS A CD2 1 ATOM 1410 C CE1 . HIS A 1 183 ? -26.064 11.392 -5.046 1.00 12.98 ? 183 HIS A CE1 1 ATOM 1411 N NE2 . HIS A 1 183 ? -26.973 12.126 -5.660 1.00 17.76 ? 183 HIS A NE2 1 ATOM 1412 N N . VAL A 1 184 ? -29.847 6.186 -5.058 1.00 16.15 ? 184 VAL A N 1 ATOM 1413 C CA . VAL A 1 184 ? -31.180 5.623 -4.883 1.00 15.79 ? 184 VAL A CA 1 ATOM 1414 C C . VAL A 1 184 ? -31.985 6.622 -4.025 1.00 16.97 ? 184 VAL A C 1 ATOM 1415 O O . VAL A 1 184 ? -31.784 6.720 -2.804 1.00 17.93 ? 184 VAL A O 1 ATOM 1416 C CB . VAL A 1 184 ? -31.132 4.185 -4.288 1.00 15.24 ? 184 VAL A CB 1 ATOM 1417 C CG1 . VAL A 1 184 ? -32.583 3.699 -3.863 1.00 12.46 ? 184 VAL A CG1 1 ATOM 1418 C CG2 . VAL A 1 184 ? -30.542 3.242 -5.300 1.00 13.81 ? 184 VAL A CG2 1 ATOM 1419 N N . HIS A 1 185 ? -32.843 7.411 -4.677 1.00 17.12 ? 185 HIS A N 1 ATOM 1420 C CA . HIS A 1 185 ? -33.631 8.454 -3.997 1.00 16.31 ? 185 HIS A CA 1 ATOM 1421 C C . HIS A 1 185 ? -34.876 7.861 -3.375 1.00 17.28 ? 185 HIS A C 1 ATOM 1422 O O . HIS A 1 185 ? -35.486 8.498 -2.498 1.00 16.86 ? 185 HIS A O 1 ATOM 1423 C CB . HIS A 1 185 ? -34.023 9.615 -4.944 1.00 16.02 ? 185 HIS A CB 1 ATOM 1424 C CG . HIS A 1 185 ? -32.836 10.371 -5.509 1.00 16.85 ? 185 HIS A CG 1 ATOM 1425 N ND1 . HIS A 1 185 ? -32.776 10.804 -6.820 1.00 14.86 ? 185 HIS A ND1 1 ATOM 1426 C CD2 . HIS A 1 185 ? -31.660 10.748 -4.937 1.00 17.89 ? 185 HIS A CD2 1 ATOM 1427 C CE1 . HIS A 1 185 ? -31.619 11.416 -7.029 1.00 19.89 ? 185 HIS A CE1 1 ATOM 1428 N NE2 . HIS A 1 185 ? -30.907 11.374 -5.911 1.00 16.39 ? 185 HIS A NE2 1 ATOM 1429 N N . GLN A 1 186 ? -35.242 6.670 -3.832 1.00 18.17 ? 186 GLN A N 1 ATOM 1430 C CA . GLN A 1 186 ? -36.449 5.929 -3.381 1.00 20.28 ? 186 GLN A CA 1 ATOM 1431 C C . GLN A 1 186 ? -37.724 6.569 -3.861 1.00 21.61 ? 186 GLN A C 1 ATOM 1432 O O . GLN A 1 186 ? -38.675 5.877 -4.139 1.00 24.49 ? 186 GLN A O 1 ATOM 1433 C CB . GLN A 1 186 ? -36.476 5.701 -1.873 1.00 19.75 ? 186 GLN A CB 1 ATOM 1434 C CG . GLN A 1 186 ? -35.129 5.180 -1.338 1.00 20.96 ? 186 GLN A CG 1 ATOM 1435 C CD . GLN A 1 186 ? -35.220 4.828 0.121 1.00 24.27 ? 186 GLN A CD 1 ATOM 1436 O OE1 . GLN A 1 186 ? -36.310 4.558 0.646 1.00 24.84 ? 186 GLN A OE1 1 ATOM 1437 N NE2 . GLN A 1 186 ? -34.104 4.837 0.781 1.00 23.70 ? 186 GLN A NE2 1 ATOM 1438 N N . GLN A 1 187 ? -37.747 7.882 -4.025 1.00 21.91 ? 187 GLN A N 1 ATOM 1439 C CA . GLN A 1 187 ? -38.905 8.507 -4.652 1.00 20.81 ? 187 GLN A CA 1 ATOM 1440 C C . GLN A 1 187 ? -38.379 9.331 -5.824 1.00 19.56 ? 187 GLN A C 1 ATOM 1441 O O . GLN A 1 187 ? -37.186 9.501 -5.954 1.00 19.25 ? 187 GLN A O 1 ATOM 1442 C CB . GLN A 1 187 ? -39.675 9.329 -3.633 1.00 21.71 ? 187 GLN A CB 1 ATOM 1443 C CG . GLN A 1 187 ? -38.832 10.473 -3.067 1.00 25.12 ? 187 GLN A CG 1 ATOM 1444 C CD . GLN A 1 187 ? -39.372 11.027 -1.751 1.00 33.05 ? 187 GLN A CD 1 ATOM 1445 O OE1 . GLN A 1 187 ? -39.919 12.140 -1.705 1.00 37.77 ? 187 GLN A OE1 1 ATOM 1446 N NE2 . GLN A 1 187 ? -39.201 10.264 -0.673 1.00 35.31 ? 187 GLN A NE2 1 ATOM 1447 N N . TYR A 1 188 ? -39.253 9.817 -6.692 1.00 18.37 ? 188 TYR A N 1 ATOM 1448 C CA . TYR A 1 188 ? -38.802 10.576 -7.840 1.00 18.09 ? 188 TYR A CA 1 ATOM 1449 C C . TYR A 1 188 ? -38.766 12.103 -7.563 1.00 18.41 ? 188 TYR A C 1 ATOM 1450 O O . TYR A 1 188 ? -37.758 12.779 -7.843 1.00 18.35 ? 188 TYR A O 1 ATOM 1451 C CB . TYR A 1 188 ? -39.672 10.235 -9.082 1.00 18.12 ? 188 TYR A CB 1 ATOM 1452 C CG . TYR A 1 188 ? -39.226 10.928 -10.347 1.00 16.32 ? 188 TYR A CG 1 ATOM 1453 C CD1 . TYR A 1 188 ? -37.925 10.785 -10.832 1.00 17.82 ? 188 TYR A CD1 1 ATOM 1454 C CD2 . TYR A 1 188 ? -40.094 11.764 -11.037 1.00 14.45 ? 188 TYR A CD2 1 ATOM 1455 C CE1 . TYR A 1 188 ? -37.493 11.433 -11.984 1.00 15.63 ? 188 TYR A CE1 1 ATOM 1456 C CE2 . TYR A 1 188 ? -39.670 12.435 -12.214 1.00 14.76 ? 188 TYR A CE2 1 ATOM 1457 C CZ . TYR A 1 188 ? -38.376 12.262 -12.662 1.00 15.68 ? 188 TYR A CZ 1 ATOM 1458 O OH . TYR A 1 188 ? -37.978 12.912 -13.802 1.00 16.43 ? 188 TYR A OH 1 ATOM 1459 N N . ARG A 1 189 ? -39.860 12.658 -7.050 1.00 17.22 ? 189 ARG A N 1 ATOM 1460 C CA . ARG A 1 189 ? -39.855 14.055 -6.649 1.00 17.44 ? 189 ARG A CA 1 ATOM 1461 C C . ARG A 1 189 ? -39.062 14.183 -5.363 1.00 18.65 ? 189 ARG A C 1 ATOM 1462 O O . ARG A 1 189 ? -39.253 13.440 -4.410 1.00 18.74 ? 189 ARG A O 1 ATOM 1463 C CB . ARG A 1 189 ? -41.243 14.606 -6.406 1.00 18.33 ? 189 ARG A CB 1 ATOM 1464 C CG . ARG A 1 189 ? -41.166 16.099 -6.140 1.00 18.20 ? 189 ARG A CG 1 ATOM 1465 C CD . ARG A 1 189 ? -42.504 16.765 -5.994 1.00 21.57 ? 189 ARG A CD 1 ATOM 1466 N NE . ARG A 1 189 ? -43.356 16.213 -4.950 1.00 25.11 ? 189 ARG A NE 1 ATOM 1467 C CZ . ARG A 1 189 ? -44.636 16.585 -4.813 1.00 31.37 ? 189 ARG A CZ 1 ATOM 1468 N NH1 . ARG A 1 189 ? -45.142 17.533 -5.607 1.00 29.51 ? 189 ARG A NH1 1 ATOM 1469 N NH2 . ARG A 1 189 ? -45.415 16.036 -3.880 1.00 31.12 ? 189 ARG A NH2 1 ATOM 1470 N N . HIS A 1 190 ? -38.152 15.123 -5.341 1.00 18.92 ? 190 HIS A N 1 ATOM 1471 C CA . HIS A 1 190 ? -37.277 15.225 -4.183 1.00 21.48 ? 190 HIS A CA 1 ATOM 1472 C C . HIS A 1 190 ? -37.923 15.560 -2.873 1.00 23.95 ? 190 HIS A C 1 ATOM 1473 O O . HIS A 1 190 ? -38.782 16.439 -2.782 1.00 24.87 ? 190 HIS A O 1 ATOM 1474 C CB . HIS A 1 190 ? -36.145 16.172 -4.470 1.00 20.55 ? 190 HIS A CB 1 ATOM 1475 C CG . HIS A 1 190 ? -34.988 15.470 -5.065 1.00 21.66 ? 190 HIS A CG 1 ATOM 1476 N ND1 . HIS A 1 190 ? -34.809 15.349 -6.425 1.00 24.36 ? 190 HIS A ND1 1 ATOM 1477 C CD2 . HIS A 1 190 ? -33.994 14.766 -4.489 1.00 22.56 ? 190 HIS A CD2 1 ATOM 1478 C CE1 . HIS A 1 190 ? -33.700 14.670 -6.662 1.00 19.61 ? 190 HIS A CE1 1 ATOM 1479 N NE2 . HIS A 1 190 ? -33.196 14.293 -5.503 1.00 24.62 ? 190 HIS A NE2 1 ATOM 1480 N N . ASP A 1 191 ? -37.512 14.808 -1.855 1.00 26.34 ? 191 ASP A N 1 ATOM 1481 C CA . ASP A 1 191 ? -37.707 15.229 -0.491 1.00 27.64 ? 191 ASP A CA 1 ATOM 1482 C C . ASP A 1 191 ? -36.842 16.476 -0.263 1.00 27.45 ? 191 ASP A C 1 ATOM 1483 O O . ASP A 1 191 ? -35.588 16.381 -0.178 1.00 25.73 ? 191 ASP A O 1 ATOM 1484 C CB . ASP A 1 191 ? -37.298 14.106 0.442 1.00 29.00 ? 191 ASP A CB 1 ATOM 1485 C CG . ASP A 1 191 ? -37.691 14.384 1.858 1.00 33.46 ? 191 ASP A CG 1 ATOM 1486 O OD1 . ASP A 1 191 ? -37.976 15.570 2.152 1.00 35.00 ? 191 ASP A OD1 1 ATOM 1487 O OD2 . ASP A 1 191 ? -37.733 13.422 2.666 1.00 39.73 ? 191 ASP A OD2 1 ATOM 1488 N N . MET A 1 192 ? -37.514 17.640 -0.203 1.00 26.93 ? 192 MET A N 1 ATOM 1489 C CA . MET A 1 192 ? -36.858 18.946 0.063 1.00 25.98 ? 192 MET A CA 1 ATOM 1490 C C . MET A 1 192 ? -36.640 19.186 1.553 1.00 26.78 ? 192 MET A C 1 ATOM 1491 O O . MET A 1 192 ? -36.235 20.268 1.934 1.00 25.85 ? 192 MET A O 1 ATOM 1492 C CB . MET A 1 192 ? -37.643 20.134 -0.552 1.00 25.47 ? 192 MET A CB 1 ATOM 1493 C CG . MET A 1 192 ? -37.745 20.166 -2.115 1.00 24.98 ? 192 MET A CG 1 ATOM 1494 S SD . MET A 1 192 ? -36.136 20.022 -2.988 1.00 26.24 ? 192 MET A SD 1 ATOM 1495 C CE . MET A 1 192 ? -35.496 21.679 -2.767 1.00 25.02 ? 192 MET A CE 1 ATOM 1496 N N . ASN A 1 193 ? -36.892 18.180 2.391 1.00 26.68 ? 193 ASN A N 1 ATOM 1497 C CA . ASN A 1 193 ? -36.764 18.336 3.830 1.00 27.87 ? 193 ASN A CA 1 ATOM 1498 C C . ASN A 1 193 ? -35.345 18.127 4.419 1.00 26.96 ? 193 ASN A C 1 ATOM 1499 O O . ASN A 1 193 ? -35.073 17.141 5.121 1.00 28.88 ? 193 ASN A O 1 ATOM 1500 C CB . ASN A 1 193 ? -37.800 17.487 4.567 1.00 29.03 ? 193 ASN A CB 1 ATOM 1501 C CG . ASN A 1 193 ? -39.214 18.081 4.488 1.00 33.16 ? 193 ASN A CG 1 ATOM 1502 O OD1 . ASN A 1 193 ? -40.198 17.343 4.412 1.00 41.17 ? 193 ASN A OD1 1 ATOM 1503 N ND2 . ASN A 1 193 ? -39.318 19.408 4.519 1.00 34.65 ? 193 ASN A ND2 1 ATOM 1504 N N . TRP A 1 194 ? -34.462 19.065 4.146 1.00 24.49 ? 194 TRP A N 1 ATOM 1505 C CA . TRP A 1 194 ? -33.094 19.028 4.677 1.00 23.25 ? 194 TRP A CA 1 ATOM 1506 C C . TRP A 1 194 ? -32.441 17.707 4.341 1.00 23.28 ? 194 TRP A C 1 ATOM 1507 O O . TRP A 1 194 ? -32.327 16.825 5.203 1.00 25.90 ? 194 TRP A O 1 ATOM 1508 C CB . TRP A 1 194 ? -33.099 19.234 6.193 1.00 21.70 ? 194 TRP A CB 1 ATOM 1509 C CG . TRP A 1 194 ? -33.818 20.478 6.632 1.00 19.70 ? 194 TRP A CG 1 ATOM 1510 C CD1 . TRP A 1 194 ? -35.094 20.557 7.180 1.00 19.08 ? 194 TRP A CD1 1 ATOM 1511 C CD2 . TRP A 1 194 ? -33.327 21.822 6.551 1.00 17.48 ? 194 TRP A CD2 1 ATOM 1512 N NE1 . TRP A 1 194 ? -35.406 21.872 7.443 1.00 16.62 ? 194 TRP A NE1 1 ATOM 1513 C CE2 . TRP A 1 194 ? -34.342 22.668 7.078 1.00 19.23 ? 194 TRP A CE2 1 ATOM 1514 C CE3 . TRP A 1 194 ? -32.106 22.397 6.106 1.00 17.52 ? 194 TRP A CE3 1 ATOM 1515 C CZ2 . TRP A 1 194 ? -34.186 24.061 7.165 1.00 17.48 ? 194 TRP A CZ2 1 ATOM 1516 C CZ3 . TRP A 1 194 ? -31.947 23.757 6.194 1.00 16.77 ? 194 TRP A CZ3 1 ATOM 1517 C CH2 . TRP A 1 194 ? -32.986 24.590 6.721 1.00 19.75 ? 194 TRP A CH2 1 ATOM 1518 N N . LYS A 1 195 ? -32.045 17.548 3.088 1.00 21.71 ? 195 LYS A N 1 ATOM 1519 C CA . LYS A 1 195 ? -31.401 16.313 2.614 1.00 20.90 ? 195 LYS A CA 1 ATOM 1520 C C . LYS A 1 195 ? -30.121 16.661 1.908 1.00 19.73 ? 195 LYS A C 1 ATOM 1521 O O . LYS A 1 195 ? -30.097 17.630 1.136 1.00 19.49 ? 195 LYS A O 1 ATOM 1522 C CB . LYS A 1 195 ? -32.322 15.558 1.653 1.00 21.47 ? 195 LYS A CB 1 ATOM 1523 C CG . LYS A 1 195 ? -33.332 14.623 2.341 1.00 27.34 ? 195 LYS A CG 1 ATOM 1524 C CD . LYS A 1 195 ? -32.628 13.363 2.948 1.00 32.11 ? 195 LYS A CD 1 ATOM 1525 C CE . LYS A 1 195 ? -31.608 12.700 1.938 1.00 33.79 ? 195 LYS A CE 1 ATOM 1526 N NZ . LYS A 1 195 ? -30.817 11.447 2.368 1.00 34.11 ? 195 LYS A NZ 1 ATOM 1527 N N . THR A 1 196 ? -29.060 15.906 2.180 1.00 17.97 ? 196 THR A N 1 ATOM 1528 C CA . THR A 1 196 ? -27.768 16.123 1.515 1.00 16.74 ? 196 THR A CA 1 ATOM 1529 C C . THR A 1 196 ? -27.381 14.884 0.681 1.00 16.42 ? 196 THR A C 1 ATOM 1530 O O . THR A 1 196 ? -27.342 13.771 1.220 1.00 16.72 ? 196 THR A O 1 ATOM 1531 C CB . THR A 1 196 ? -26.620 16.451 2.544 1.00 17.26 ? 196 THR A CB 1 ATOM 1532 O OG1 . THR A 1 196 ? -26.901 17.673 3.266 1.00 17.76 ? 196 THR A OG1 1 ATOM 1533 C CG2 . THR A 1 196 ? -25.308 16.621 1.837 1.00 18.33 ? 196 THR A CG2 1 ATOM 1534 N N . TRP A 1 197 ? -27.057 15.082 -0.606 1.00 16.40 ? 197 TRP A N 1 ATOM 1535 C CA . TRP A 1 197 ? -26.752 14.005 -1.560 1.00 15.60 ? 197 TRP A CA 1 ATOM 1536 C C . TRP A 1 197 ? -25.326 14.135 -2.035 1.00 15.26 ? 197 TRP A C 1 ATOM 1537 O O . TRP A 1 197 ? -25.009 15.083 -2.761 1.00 15.78 ? 197 TRP A O 1 ATOM 1538 C CB . TRP A 1 197 ? -27.690 14.039 -2.776 1.00 16.19 ? 197 TRP A CB 1 ATOM 1539 C CG . TRP A 1 197 ? -29.129 13.704 -2.377 1.00 15.01 ? 197 TRP A CG 1 ATOM 1540 C CD1 . TRP A 1 197 ? -30.141 14.592 -2.155 1.00 19.14 ? 197 TRP A CD1 1 ATOM 1541 C CD2 . TRP A 1 197 ? -29.663 12.402 -2.090 1.00 17.10 ? 197 TRP A CD2 1 ATOM 1542 N NE1 . TRP A 1 197 ? -31.288 13.918 -1.765 1.00 18.92 ? 197 TRP A NE1 1 ATOM 1543 C CE2 . TRP A 1 197 ? -31.019 12.575 -1.718 1.00 17.67 ? 197 TRP A CE2 1 ATOM 1544 C CE3 . TRP A 1 197 ? -29.126 11.095 -2.110 1.00 17.84 ? 197 TRP A CE3 1 ATOM 1545 C CZ2 . TRP A 1 197 ? -31.846 11.493 -1.398 1.00 16.66 ? 197 TRP A CZ2 1 ATOM 1546 C CZ3 . TRP A 1 197 ? -29.947 10.029 -1.792 1.00 18.65 ? 197 TRP A CZ3 1 ATOM 1547 C CH2 . TRP A 1 197 ? -31.298 10.232 -1.433 1.00 16.94 ? 197 TRP A CH2 1 ATOM 1548 N N . PRO A 1 198 ? -24.458 13.211 -1.608 1.00 15.45 ? 198 PRO A N 1 ATOM 1549 C CA . PRO A 1 198 ? -23.086 13.314 -2.062 1.00 14.84 ? 198 PRO A CA 1 ATOM 1550 C C . PRO A 1 198 ? -22.954 12.741 -3.476 1.00 14.91 ? 198 PRO A C 1 ATOM 1551 O O . PRO A 1 198 ? -23.661 11.802 -3.828 1.00 14.75 ? 198 PRO A O 1 ATOM 1552 C CB . PRO A 1 198 ? -22.347 12.459 -1.037 1.00 15.13 ? 198 PRO A CB 1 ATOM 1553 C CG . PRO A 1 198 ? -23.341 11.364 -0.680 1.00 16.56 ? 198 PRO A CG 1 ATOM 1554 C CD . PRO A 1 198 ? -24.659 12.093 -0.655 1.00 14.36 ? 198 PRO A CD 1 ATOM 1555 N N . ILE A 1 199 ? -22.065 13.301 -4.288 1.00 14.42 ? 199 ILE A N 1 ATOM 1556 C CA . ILE A 1 199 ? -21.868 12.828 -5.632 1.00 14.41 ? 199 ILE A CA 1 ATOM 1557 C C . ILE A 1 199 ? -20.373 12.612 -5.799 1.00 14.63 ? 199 ILE A C 1 ATOM 1558 O O . ILE A 1 199 ? -19.592 13.564 -5.743 1.00 13.91 ? 199 ILE A O 1 ATOM 1559 C CB . ILE A 1 199 ? -22.356 13.876 -6.663 1.00 15.51 ? 199 ILE A CB 1 ATOM 1560 C CG1 . ILE A 1 199 ? -23.866 14.132 -6.440 1.00 16.16 ? 199 ILE A CG1 1 ATOM 1561 C CG2 . ILE A 1 199 ? -22.032 13.400 -8.095 1.00 15.11 ? 199 ILE A CG2 1 ATOM 1562 C CD1 . ILE A 1 199 ? -24.455 15.286 -7.275 1.00 16.36 ? 199 ILE A CD1 1 ATOM 1563 N N . PHE A 1 200 ? -20.002 11.353 -5.977 1.00 14.05 ? 200 PHE A N 1 ATOM 1564 C CA . PHE A 1 200 ? -18.585 10.988 -6.185 1.00 14.98 ? 200 PHE A CA 1 ATOM 1565 C C . PHE A 1 200 ? -18.600 9.533 -6.581 1.00 14.72 ? 200 PHE A C 1 ATOM 1566 O O . PHE A 1 200 ? -19.032 8.655 -5.804 1.00 16.33 ? 200 PHE A O 1 ATOM 1567 C CB . PHE A 1 200 ? -17.819 11.147 -4.888 1.00 15.22 ? 200 PHE A CB 1 ATOM 1568 C CG . PHE A 1 200 ? -16.344 10.969 -5.062 1.00 16.54 ? 200 PHE A CG 1 ATOM 1569 C CD1 . PHE A 1 200 ? -15.627 11.878 -5.804 1.00 16.54 ? 200 PHE A CD1 1 ATOM 1570 C CD2 . PHE A 1 200 ? -15.727 9.877 -4.522 1.00 17.31 ? 200 PHE A CD2 1 ATOM 1571 C CE1 . PHE A 1 200 ? -14.224 11.729 -5.965 1.00 17.76 ? 200 PHE A CE1 1 ATOM 1572 C CE2 . PHE A 1 200 ? -14.348 9.706 -4.697 1.00 21.43 ? 200 PHE A CE2 1 ATOM 1573 C CZ . PHE A 1 200 ? -13.634 10.625 -5.410 1.00 17.29 ? 200 PHE A CZ 1 ATOM 1574 N N . ASN A 1 201 ? -18.154 9.282 -7.801 1.00 15.55 ? 201 ASN A N 1 ATOM 1575 C CA . ASN A 1 201 ? -18.311 7.984 -8.429 1.00 14.86 ? 201 ASN A CA 1 ATOM 1576 C C . ASN A 1 201 ? -17.732 6.891 -7.585 1.00 16.35 ? 201 ASN A C 1 ATOM 1577 O O . ASN A 1 201 ? -16.548 6.906 -7.216 1.00 15.19 ? 201 ASN A O 1 ATOM 1578 C CB . ASN A 1 201 ? -17.703 8.012 -9.802 1.00 16.24 ? 201 ASN A CB 1 ATOM 1579 C CG . ASN A 1 201 ? -18.493 8.893 -10.748 1.00 14.11 ? 201 ASN A CG 1 ATOM 1580 O OD1 . ASN A 1 201 ? -19.529 9.446 -10.358 1.00 21.23 ? 201 ASN A OD1 1 ATOM 1581 N ND2 . ASN A 1 201 ? -18.074 8.963 -12.004 1.00 14.78 ? 201 ASN A ND2 1 ATOM 1582 N N . ARG A 1 202 ? -18.573 5.939 -7.262 1.00 15.11 ? 202 ARG A N 1 ATOM 1583 C CA . ARG A 1 202 ? -18.190 4.937 -6.244 1.00 15.86 ? 202 ARG A CA 1 ATOM 1584 C C . ARG A 1 202 ? -18.909 3.627 -6.467 1.00 16.81 ? 202 ARG A C 1 ATOM 1585 O O . ARG A 1 202 ? -20.162 3.578 -6.694 1.00 14.85 ? 202 ARG A O 1 ATOM 1586 C CB . ARG A 1 202 ? -18.439 5.483 -4.828 1.00 15.46 ? 202 ARG A CB 1 ATOM 1587 C CG . ARG A 1 202 ? -18.432 4.452 -3.700 1.00 15.79 ? 202 ARG A CG 1 ATOM 1588 C CD . ARG A 1 202 ? -17.009 3.923 -3.446 1.00 17.84 ? 202 ARG A CD 1 ATOM 1589 N NE . ARG A 1 202 ? -17.077 2.742 -2.577 1.00 21.06 ? 202 ARG A NE 1 ATOM 1590 C CZ . ARG A 1 202 ? -16.846 2.751 -1.261 1.00 22.83 ? 202 ARG A CZ 1 ATOM 1591 N NH1 . ARG A 1 202 ? -16.507 3.872 -0.634 1.00 20.16 ? 202 ARG A NH1 1 ATOM 1592 N NH2 . ARG A 1 202 ? -16.969 1.626 -0.573 1.00 22.36 ? 202 ARG A NH2 1 ATOM 1593 N N . ASP A 1 203 ? -18.117 2.557 -6.414 1.00 18.55 ? 203 ASP A N 1 ATOM 1594 C CA . ASP A 1 203 ? -18.619 1.204 -6.413 1.00 20.38 ? 203 ASP A CA 1 ATOM 1595 C C . ASP A 1 203 ? -19.244 0.905 -5.061 1.00 20.97 ? 203 ASP A C 1 ATOM 1596 O O . ASP A 1 203 ? -18.532 0.616 -4.084 1.00 20.40 ? 203 ASP A O 1 ATOM 1597 C CB . ASP A 1 203 ? -17.443 0.244 -6.697 1.00 20.93 ? 203 ASP A CB 1 ATOM 1598 C CG . ASP A 1 203 ? -17.862 -1.229 -6.760 1.00 23.62 ? 203 ASP A CG 1 ATOM 1599 O OD1 . ASP A 1 203 ? -19.071 -1.562 -6.607 1.00 24.39 ? 203 ASP A OD1 1 ATOM 1600 O OD2 . ASP A 1 203 ? -16.938 -2.048 -6.996 1.00 27.53 ? 203 ASP A OD2 1 ATOM 1601 N N . THR A 1 204 ? -20.566 1.023 -4.975 1.00 21.12 ? 204 THR A N 1 ATOM 1602 C CA . THR A 1 204 ? -21.256 0.542 -3.807 1.00 23.93 ? 204 THR A CA 1 ATOM 1603 C C . THR A 1 204 ? -22.655 0.183 -4.090 1.00 22.67 ? 204 THR A C 1 ATOM 1604 O O . THR A 1 204 ? -23.163 0.467 -5.157 1.00 23.10 ? 204 THR A O 1 ATOM 1605 C CB . THR A 1 204 ? -21.341 1.505 -2.680 1.00 24.87 ? 204 THR A CB 1 ATOM 1606 O OG1 . THR A 1 204 ? -21.565 2.816 -3.169 1.00 28.30 ? 204 THR A OG1 1 ATOM 1607 C CG2 . THR A 1 204 ? -20.072 1.420 -1.839 1.00 30.85 ? 204 THR A CG2 1 ATOM 1608 N N . THR A 1 205 ? -23.286 -0.430 -3.105 1.00 21.62 ? 205 THR A N 1 ATOM 1609 C CA . THR A 1 205 ? -24.569 -1.041 -3.327 1.00 21.89 ? 205 THR A CA 1 ATOM 1610 C C . THR A 1 205 ? -25.667 0.008 -3.413 1.00 21.14 ? 205 THR A C 1 ATOM 1611 O O . THR A 1 205 ? -25.808 0.834 -2.522 1.00 20.71 ? 205 THR A O 1 ATOM 1612 C CB . THR A 1 205 ? -24.897 -2.025 -2.209 1.00 22.98 ? 205 THR A CB 1 ATOM 1613 O OG1 . THR A 1 205 ? -23.807 -2.931 -2.059 1.00 27.00 ? 205 THR A OG1 1 ATOM 1614 C CG2 . THR A 1 205 ? -26.142 -2.806 -2.551 1.00 20.35 ? 205 THR A CG2 1 ATOM 1615 N N . PRO A 1 206 ? -26.456 -0.034 -4.492 1.00 20.80 ? 206 PRO A N 1 ATOM 1616 C CA . PRO A 1 206 ? -27.635 0.826 -4.545 1.00 20.81 ? 206 PRO A CA 1 ATOM 1617 C C . PRO A 1 206 ? -28.714 0.365 -3.579 1.00 21.58 ? 206 PRO A C 1 ATOM 1618 O O . PRO A 1 206 ? -29.669 -0.321 -3.970 1.00 23.85 ? 206 PRO A O 1 ATOM 1619 C CB . PRO A 1 206 ? -28.131 0.684 -5.979 1.00 20.11 ? 206 PRO A CB 1 ATOM 1620 C CG . PRO A 1 206 ? -27.602 -0.678 -6.441 1.00 21.22 ? 206 PRO A CG 1 ATOM 1621 C CD . PRO A 1 206 ? -26.288 -0.871 -5.700 1.00 20.67 ? 206 PRO A CD 1 ATOM 1622 N N . ASN A 1 207 ? -28.637 0.826 -2.349 1.00 21.66 ? 207 ASN A N 1 ATOM 1623 C CA . ASN A 1 207 ? -29.584 0.358 -1.323 1.00 21.70 ? 207 ASN A CA 1 ATOM 1624 C C . ASN A 1 207 ? -30.321 1.534 -0.686 1.00 21.55 ? 207 ASN A C 1 ATOM 1625 O O . ASN A 1 207 ? -30.323 2.652 -1.223 1.00 21.09 ? 207 ASN A O 1 ATOM 1626 C CB . ASN A 1 207 ? -28.821 -0.489 -0.282 1.00 22.15 ? 207 ASN A CB 1 ATOM 1627 C CG . ASN A 1 207 ? -27.670 0.272 0.337 1.00 23.29 ? 207 ASN A CG 1 ATOM 1628 O OD1 . ASN A 1 207 ? -27.729 1.487 0.425 1.00 26.09 ? 207 ASN A OD1 1 ATOM 1629 N ND2 . ASN A 1 207 ? -26.617 -0.429 0.761 1.00 24.59 ? 207 ASN A ND2 1 ATOM 1630 N N . GLY A 1 208 ? -30.916 1.297 0.475 1.00 21.11 ? 208 GLY A N 1 ATOM 1631 C CA . GLY A 1 208 ? -31.654 2.344 1.192 1.00 22.23 ? 208 GLY A CA 1 ATOM 1632 C C . GLY A 1 208 ? -30.851 3.404 1.913 1.00 22.67 ? 208 GLY A C 1 ATOM 1633 O O . GLY A 1 208 ? -31.436 4.271 2.522 1.00 22.38 ? 208 GLY A O 1 ATOM 1634 N N . ASN A 1 209 ? -29.517 3.344 1.846 1.00 23.35 ? 209 ASN A N 1 ATOM 1635 C CA . ASN A 1 209 ? -28.667 4.266 2.602 1.00 23.76 ? 209 ASN A CA 1 ATOM 1636 C C . ASN A 1 209 ? -28.380 5.612 1.946 1.00 23.19 ? 209 ASN A C 1 ATOM 1637 O O . ASN A 1 209 ? -27.741 6.475 2.560 1.00 23.72 ? 209 ASN A O 1 ATOM 1638 C CB . ASN A 1 209 ? -27.337 3.590 2.982 1.00 24.45 ? 209 ASN A CB 1 ATOM 1639 C CG . ASN A 1 209 ? -27.536 2.503 4.012 1.00 31.07 ? 209 ASN A CG 1 ATOM 1640 O OD1 . ASN A 1 209 ? -28.280 2.696 4.988 1.00 35.58 ? 209 ASN A OD1 1 ATOM 1641 N ND2 . ASN A 1 209 ? -26.947 1.330 3.766 1.00 38.41 ? 209 ASN A ND2 1 ATOM 1642 N N . GLY A 1 210 ? -28.829 5.794 0.713 1.00 21.86 ? 210 GLY A N 1 ATOM 1643 C CA . GLY A 1 210 ? -28.705 7.095 0.051 1.00 20.75 ? 210 GLY A CA 1 ATOM 1644 C C . GLY A 1 210 ? -27.286 7.620 -0.114 1.00 19.55 ? 210 GLY A C 1 ATOM 1645 O O . GLY A 1 210 ? -27.059 8.834 0.003 1.00 20.15 ? 210 GLY A O 1 ATOM 1646 N N . THR A 1 211 ? -26.340 6.718 -0.380 1.00 18.08 ? 211 THR A N 1 ATOM 1647 C CA . THR A 1 211 ? -24.946 7.094 -0.672 1.00 17.21 ? 211 THR A CA 1 ATOM 1648 C C . THR A 1 211 ? -24.699 7.571 -2.107 1.00 16.27 ? 211 THR A C 1 ATOM 1649 O O . THR A 1 211 ? -25.546 7.420 -3.015 1.00 15.30 ? 211 THR A O 1 ATOM 1650 C CB . THR A 1 211 ? -23.948 5.896 -0.371 1.00 16.41 ? 211 THR A CB 1 ATOM 1651 O OG1 . THR A 1 211 ? -24.032 4.903 -1.407 1.00 17.78 ? 211 THR A OG1 1 ATOM 1652 C CG2 . THR A 1 211 ? -24.274 5.226 0.961 1.00 17.73 ? 211 THR A CG2 1 ATOM 1653 N N . ASN A 1 212 ? -23.491 8.092 -2.342 1.00 14.73 ? 212 ASN A N 1 ATOM 1654 C CA . ASN A 1 212 ? -23.026 8.249 -3.697 1.00 14.91 ? 212 ASN A CA 1 ATOM 1655 C C . ASN A 1 212 ? -22.873 6.877 -4.343 1.00 15.01 ? 212 ASN A C 1 ATOM 1656 O O . ASN A 1 212 ? -22.487 5.914 -3.684 1.00 15.19 ? 212 ASN A O 1 ATOM 1657 C CB . ASN A 1 212 ? -21.643 8.935 -3.692 1.00 14.00 ? 212 ASN A CB 1 ATOM 1658 C CG . ASN A 1 212 ? -20.715 8.372 -2.630 1.00 15.52 ? 212 ASN A CG 1 ATOM 1659 O OD1 . ASN A 1 212 ? -21.101 8.202 -1.454 1.00 15.45 ? 212 ASN A OD1 1 ATOM 1660 N ND2 . ASN A 1 212 ? -19.445 8.133 -3.031 1.00 14.23 ? 212 ASN A ND2 1 ATOM 1661 N N . LEU A 1 213 ? -23.194 6.776 -5.625 1.00 14.08 ? 213 LEU A N 1 ATOM 1662 C CA . LEU A 1 213 ? -23.072 5.510 -6.331 1.00 13.62 ? 213 LEU A CA 1 ATOM 1663 C C . LEU A 1 213 ? -22.180 5.701 -7.554 1.00 14.39 ? 213 LEU A C 1 ATOM 1664 O O . LEU A 1 213 ? -21.273 6.527 -7.543 1.00 14.83 ? 213 LEU A O 1 ATOM 1665 C CB . LEU A 1 213 ? -24.482 4.965 -6.696 1.00 12.80 ? 213 LEU A CB 1 ATOM 1666 C CG . LEU A 1 213 ? -25.357 4.738 -5.469 1.00 12.88 ? 213 LEU A CG 1 ATOM 1667 C CD1 . LEU A 1 213 ? -26.774 4.513 -6.068 1.00 10.47 ? 213 LEU A CD1 1 ATOM 1668 C CD2 . LEU A 1 213 ? -24.934 3.595 -4.552 1.00 16.18 ? 213 LEU A CD2 1 ATOM 1669 N N . TYR A 1 214 ? -22.408 4.945 -8.610 1.00 15.32 ? 214 TYR A N 1 ATOM 1670 C CA . TYR A 1 214 ? -21.402 4.773 -9.655 1.00 15.38 ? 214 TYR A CA 1 ATOM 1671 C C . TYR A 1 214 ? -21.136 5.999 -10.531 1.00 17.38 ? 214 TYR A C 1 ATOM 1672 O O . TYR A 1 214 ? -20.018 6.128 -11.050 1.00 16.99 ? 214 TYR A O 1 ATOM 1673 C CB . TYR A 1 214 ? -21.797 3.618 -10.576 1.00 15.43 ? 214 TYR A CB 1 ATOM 1674 C CG . TYR A 1 214 ? -22.317 2.460 -9.834 1.00 16.23 ? 214 TYR A CG 1 ATOM 1675 C CD1 . TYR A 1 214 ? -21.435 1.592 -9.189 1.00 14.96 ? 214 TYR A CD1 1 ATOM 1676 C CD2 . TYR A 1 214 ? -23.682 2.223 -9.736 1.00 12.40 ? 214 TYR A CD2 1 ATOM 1677 C CE1 . TYR A 1 214 ? -21.890 0.492 -8.463 1.00 16.25 ? 214 TYR A CE1 1 ATOM 1678 C CE2 . TYR A 1 214 ? -24.142 1.123 -8.998 1.00 17.44 ? 214 TYR A CE2 1 ATOM 1679 C CZ . TYR A 1 214 ? -23.250 0.271 -8.395 1.00 15.28 ? 214 TYR A CZ 1 ATOM 1680 O OH . TYR A 1 214 ? -23.647 -0.847 -7.721 1.00 17.92 ? 214 TYR A OH 1 ATOM 1681 N N . GLY A 1 215 ? -22.146 6.880 -10.677 1.00 15.88 ? 215 GLY A N 1 ATOM 1682 C CA . GLY A 1 215 ? -22.058 8.011 -11.609 1.00 16.04 ? 215 GLY A CA 1 ATOM 1683 C C . GLY A 1 215 ? -22.208 9.389 -10.985 1.00 14.57 ? 215 GLY A C 1 ATOM 1684 O O . GLY A 1 215 ? -22.538 9.514 -9.830 1.00 16.32 ? 215 GLY A O 1 ATOM 1685 N N . ALA A 1 216 ? -21.985 10.435 -11.762 1.00 14.50 ? 216 ALA A N 1 ATOM 1686 C CA . ALA A 1 216 ? -22.031 11.778 -11.229 1.00 14.60 ? 216 ALA A CA 1 ATOM 1687 C C . ALA A 1 216 ? -22.882 12.623 -12.158 1.00 14.78 ? 216 ALA A C 1 ATOM 1688 O O . ALA A 1 216 ? -22.510 12.842 -13.312 1.00 15.51 ? 216 ALA A O 1 ATOM 1689 C CB . ALA A 1 216 ? -20.584 12.378 -11.142 1.00 15.05 ? 216 ALA A CB 1 ATOM 1690 N N . GLN A 1 217 ? -24.027 13.068 -11.665 1.00 14.89 ? 217 GLN A N 1 ATOM 1691 C CA . GLN A 1 217 ? -25.036 13.747 -12.503 1.00 15.39 ? 217 GLN A CA 1 ATOM 1692 C C . GLN A 1 217 ? -25.602 14.958 -11.713 1.00 16.14 ? 217 GLN A C 1 ATOM 1693 O O . GLN A 1 217 ? -26.369 14.769 -10.756 1.00 15.74 ? 217 GLN A O 1 ATOM 1694 C CB . GLN A 1 217 ? -26.160 12.776 -12.895 1.00 15.22 ? 217 GLN A CB 1 ATOM 1695 C CG . GLN A 1 217 ? -25.724 11.488 -13.708 1.00 13.85 ? 217 GLN A CG 1 ATOM 1696 C CD . GLN A 1 217 ? -25.308 11.819 -15.116 1.00 16.09 ? 217 GLN A CD 1 ATOM 1697 O OE1 . GLN A 1 217 ? -25.608 12.905 -15.644 1.00 14.97 ? 217 GLN A OE1 1 ATOM 1698 N NE2 . GLN A 1 217 ? -24.603 10.909 -15.736 1.00 15.19 ? 217 GLN A NE2 1 ATOM 1699 N N . THR A 1 218 ? -25.162 16.181 -12.055 1.00 15.09 ? 218 THR A N 1 ATOM 1700 C CA . THR A 1 218 ? -25.525 17.347 -11.259 1.00 16.36 ? 218 THR A CA 1 ATOM 1701 C C . THR A 1 218 ? -26.798 18.041 -11.797 1.00 15.56 ? 218 THR A C 1 ATOM 1702 O O . THR A 1 218 ? -27.322 18.980 -11.183 1.00 18.13 ? 218 THR A O 1 ATOM 1703 C CB . THR A 1 218 ? -24.417 18.371 -11.237 1.00 16.88 ? 218 THR A CB 1 ATOM 1704 O OG1 . THR A 1 218 ? -24.202 18.834 -12.568 1.00 17.83 ? 218 THR A OG1 1 ATOM 1705 C CG2 . THR A 1 218 ? -23.094 17.762 -10.720 1.00 15.41 ? 218 THR A CG2 1 ATOM 1706 N N . PHE A 1 219 ? -27.305 17.557 -12.919 1.00 14.96 ? 219 PHE A N 1 ATOM 1707 C CA . PHE A 1 219 ? -28.523 18.126 -13.476 1.00 13.24 ? 219 PHE A CA 1 ATOM 1708 C C . PHE A 1 219 ? -29.761 17.920 -12.587 1.00 14.16 ? 219 PHE A C 1 ATOM 1709 O O . PHE A 1 219 ? -30.045 16.824 -12.096 1.00 13.89 ? 219 PHE A O 1 ATOM 1710 C CB . PHE A 1 219 ? -28.779 17.536 -14.864 1.00 13.90 ? 219 PHE A CB 1 ATOM 1711 C CG . PHE A 1 219 ? -30.081 18.045 -15.515 1.00 12.91 ? 219 PHE A CG 1 ATOM 1712 C CD1 . PHE A 1 219 ? -30.146 19.358 -15.998 1.00 13.51 ? 219 PHE A CD1 1 ATOM 1713 C CD2 . PHE A 1 219 ? -31.207 17.229 -15.597 1.00 16.22 ? 219 PHE A CD2 1 ATOM 1714 C CE1 . PHE A 1 219 ? -31.319 19.868 -16.581 1.00 15.58 ? 219 PHE A CE1 1 ATOM 1715 C CE2 . PHE A 1 219 ? -32.391 17.725 -16.182 1.00 16.14 ? 219 PHE A CE2 1 ATOM 1716 C CZ . PHE A 1 219 ? -32.440 19.038 -16.679 1.00 13.51 ? 219 PHE A CZ 1 ATOM 1717 N N . PHE A 1 220 ? -30.549 18.977 -12.442 1.00 14.61 ? 220 PHE A N 1 ATOM 1718 C CA . PHE A 1 220 ? -31.931 18.787 -11.967 1.00 14.65 ? 220 PHE A CA 1 ATOM 1719 C C . PHE A 1 220 ? -32.913 19.623 -12.763 1.00 14.57 ? 220 PHE A C 1 ATOM 1720 O O . PHE A 1 220 ? -32.534 20.590 -13.371 1.00 13.74 ? 220 PHE A O 1 ATOM 1721 C CB . PHE A 1 220 ? -32.054 19.093 -10.473 1.00 16.48 ? 220 PHE A CB 1 ATOM 1722 C CG . PHE A 1 220 ? -32.021 20.570 -10.135 1.00 18.54 ? 220 PHE A CG 1 ATOM 1723 C CD1 . PHE A 1 220 ? -33.201 21.335 -10.153 1.00 17.88 ? 220 PHE A CD1 1 ATOM 1724 C CD2 . PHE A 1 220 ? -30.807 21.206 -9.808 1.00 20.00 ? 220 PHE A CD2 1 ATOM 1725 C CE1 . PHE A 1 220 ? -33.184 22.689 -9.851 1.00 20.07 ? 220 PHE A CE1 1 ATOM 1726 C CE2 . PHE A 1 220 ? -30.780 22.573 -9.502 1.00 19.25 ? 220 PHE A CE2 1 ATOM 1727 C CZ . PHE A 1 220 ? -31.980 23.310 -9.505 1.00 21.03 ? 220 PHE A CZ 1 ATOM 1728 N N . LEU A 1 221 ? -34.195 19.249 -12.692 1.00 13.63 ? 221 LEU A N 1 ATOM 1729 C CA . LEU A 1 221 ? -35.258 19.900 -13.400 1.00 15.46 ? 221 LEU A CA 1 ATOM 1730 C C . LEU A 1 221 ? -36.280 20.314 -12.346 1.00 14.89 ? 221 LEU A C 1 ATOM 1731 O O . LEU A 1 221 ? -36.545 19.554 -11.413 1.00 13.85 ? 221 LEU A O 1 ATOM 1732 C CB . LEU A 1 221 ? -35.955 18.883 -14.339 1.00 14.55 ? 221 LEU A CB 1 ATOM 1733 C CG . LEU A 1 221 ? -37.039 19.374 -15.282 1.00 17.54 ? 221 LEU A CG 1 ATOM 1734 C CD1 . LEU A 1 221 ? -36.967 18.549 -16.548 1.00 18.10 ? 221 LEU A CD1 1 ATOM 1735 C CD2 . LEU A 1 221 ? -38.381 19.111 -14.591 1.00 17.85 ? 221 LEU A CD2 1 ATOM 1736 N N . CYS A 1 222 ? -36.859 21.494 -12.529 1.00 15.88 ? 222 CYS A N 1 ATOM 1737 C CA . CYS A 1 222 ? -37.910 22.000 -11.647 1.00 15.59 ? 222 CYS A CA 1 ATOM 1738 C C . CYS A 1 222 ? -39.130 22.366 -12.469 1.00 16.21 ? 222 CYS A C 1 ATOM 1739 O O . CYS A 1 222 ? -39.049 23.202 -13.374 1.00 15.60 ? 222 CYS A O 1 ATOM 1740 C CB . CYS A 1 222 ? -37.407 23.224 -10.920 1.00 16.24 ? 222 CYS A CB 1 ATOM 1741 S SG . CYS A 1 222 ? -38.608 23.959 -9.809 1.00 20.11 ? 222 CYS A SG 1 ATOM 1742 N N . LEU A 1 223 ? -40.244 21.741 -12.128 1.00 16.24 ? 223 LEU A N 1 ATOM 1743 C CA . LEU A 1 223 ? -41.542 22.113 -12.701 1.00 16.81 ? 223 LEU A CA 1 ATOM 1744 C C . LEU A 1 223 ? -42.133 23.235 -11.808 1.00 17.50 ? 223 LEU A C 1 ATOM 1745 O O . LEU A 1 223 ? -42.487 23.012 -10.654 1.00 17.86 ? 223 LEU A O 1 ATOM 1746 C CB . LEU A 1 223 ? -42.471 20.911 -12.749 1.00 17.38 ? 223 LEU A CB 1 ATOM 1747 C CG . LEU A 1 223 ? -43.957 21.204 -13.068 1.00 15.70 ? 223 LEU A CG 1 ATOM 1748 C CD1 . LEU A 1 223 ? -44.153 21.715 -14.483 1.00 12.47 ? 223 LEU A CD1 1 ATOM 1749 C CD2 . LEU A 1 223 ? -44.871 20.002 -12.783 1.00 18.07 ? 223 LEU A CD2 1 ATOM 1750 N N . GLU A 1 224 ? -42.244 24.422 -12.391 1.00 18.37 ? 224 GLU A N 1 ATOM 1751 C CA . GLU A 1 224 ? -42.622 25.645 -11.685 1.00 18.46 ? 224 GLU A CA 1 ATOM 1752 C C . GLU A 1 224 ? -44.066 25.634 -11.235 1.00 19.68 ? 224 GLU A C 1 ATOM 1753 O O . GLU A 1 224 ? -44.337 26.039 -10.125 1.00 19.57 ? 224 GLU A O 1 ATOM 1754 C CB . GLU A 1 224 ? -42.352 26.859 -12.585 1.00 18.63 ? 224 GLU A CB 1 ATOM 1755 C CG . GLU A 1 224 ? -40.846 27.022 -12.905 1.00 20.21 ? 224 GLU A CG 1 ATOM 1756 C CD . GLU A 1 224 ? -40.575 27.876 -14.141 1.00 22.64 ? 224 GLU A CD 1 ATOM 1757 O OE1 . GLU A 1 224 ? -41.235 28.938 -14.342 1.00 24.02 ? 224 GLU A OE1 1 ATOM 1758 O OE2 . GLU A 1 224 ? -39.650 27.502 -14.883 1.00 23.99 ? 224 GLU A OE2 1 ATOM 1759 N N . ASP A 1 225 ? -44.981 25.164 -12.085 1.00 20.30 ? 225 ASP A N 1 ATOM 1760 C CA . ASP A 1 225 ? -46.408 25.183 -11.750 1.00 21.69 ? 225 ASP A CA 1 ATOM 1761 C C . ASP A 1 225 ? -47.188 24.363 -12.772 1.00 21.30 ? 225 ASP A C 1 ATOM 1762 O O . ASP A 1 225 ? -46.609 23.844 -13.742 1.00 20.94 ? 225 ASP A O 1 ATOM 1763 C CB . ASP A 1 225 ? -46.924 26.640 -11.694 1.00 22.25 ? 225 ASP A CB 1 ATOM 1764 C CG . ASP A 1 225 ? -46.709 27.420 -13.001 1.00 26.07 ? 225 ASP A CG 1 ATOM 1765 O OD1 . ASP A 1 225 ? -47.113 26.964 -14.116 1.00 28.90 ? 225 ASP A OD1 1 ATOM 1766 O OD2 . ASP A 1 225 ? -46.133 28.542 -12.930 1.00 32.88 ? 225 ASP A OD2 1 ATOM 1767 N N . ALA A 1 226 ? -48.493 24.259 -12.559 1.00 21.16 ? 226 ALA A N 1 ATOM 1768 C CA . ALA A 1 226 ? -49.354 23.444 -13.410 1.00 20.26 ? 226 ALA A CA 1 ATOM 1769 C C . ALA A 1 226 ? -49.417 23.873 -14.872 1.00 20.48 ? 226 ALA A C 1 ATOM 1770 O O . ALA A 1 226 ? -49.930 23.122 -15.698 1.00 21.44 ? 226 ALA A O 1 ATOM 1771 C CB . ALA A 1 226 ? -50.768 23.356 -12.809 1.00 21.18 ? 226 ALA A CB 1 ATOM 1772 N N . SER A 1 227 ? -48.926 25.059 -15.228 1.00 19.36 ? 227 SER A N 1 ATOM 1773 C CA . SER A 1 227 ? -48.913 25.438 -16.631 1.00 20.35 ? 227 SER A CA 1 ATOM 1774 C C . SER A 1 227 ? -47.875 24.650 -17.446 1.00 20.56 ? 227 SER A C 1 ATOM 1775 O O . SER A 1 227 ? -47.960 24.617 -18.680 1.00 20.81 ? 227 SER A O 1 ATOM 1776 C CB . SER A 1 227 ? -48.644 26.929 -16.820 1.00 21.33 ? 227 SER A CB 1 ATOM 1777 O OG . SER A 1 227 ? -47.333 27.224 -16.337 1.00 24.70 ? 227 SER A OG 1 ATOM 1778 N N . GLY A 1 228 ? -46.918 24.021 -16.756 1.00 18.06 ? 228 GLY A N 1 ATOM 1779 C CA . GLY A 1 228 ? -45.904 23.235 -17.443 1.00 16.46 ? 228 GLY A CA 1 ATOM 1780 C C . GLY A 1 228 ? -44.565 23.941 -17.453 1.00 15.70 ? 228 GLY A C 1 ATOM 1781 O O . GLY A 1 228 ? -43.539 23.321 -17.697 1.00 14.46 ? 228 GLY A O 1 ATOM 1782 N N . LEU A 1 229 ? -44.569 25.249 -17.195 1.00 15.49 ? 229 LEU A N 1 ATOM 1783 C CA . LEU A 1 229 ? -43.331 26.035 -17.250 1.00 15.12 ? 229 LEU A CA 1 ATOM 1784 C C . LEU A 1 229 ? -42.320 25.382 -16.291 1.00 15.39 ? 229 LEU A C 1 ATOM 1785 O O . LEU A 1 229 ? -42.673 25.067 -15.153 1.00 14.96 ? 229 LEU A O 1 ATOM 1786 C CB . LEU A 1 229 ? -43.573 27.485 -16.821 1.00 15.37 ? 229 LEU A CB 1 ATOM 1787 C CG . LEU A 1 229 ? -44.405 28.322 -17.834 1.00 13.96 ? 229 LEU A CG 1 ATOM 1788 C CD1 . LEU A 1 229 ? -44.638 29.728 -17.309 1.00 17.25 ? 229 LEU A CD1 1 ATOM 1789 C CD2 . LEU A 1 229 ? -43.861 28.331 -19.227 1.00 14.77 ? 229 LEU A CD2 1 ATOM 1790 N N . SER A 1 230 ? -41.102 25.165 -16.780 1.00 15.74 ? 230 SER A N 1 ATOM 1791 C CA . SER A 1 230 ? -40.116 24.356 -16.053 1.00 15.17 ? 230 SER A CA 1 ATOM 1792 C C . SER A 1 230 ? -38.735 24.942 -16.372 1.00 14.67 ? 230 SER A C 1 ATOM 1793 O O . SER A 1 230 ? -38.538 25.642 -17.381 1.00 12.60 ? 230 SER A O 1 ATOM 1794 C CB . SER A 1 230 ? -40.151 22.879 -16.517 1.00 13.89 ? 230 SER A CB 1 ATOM 1795 O OG . SER A 1 230 ? -41.402 22.246 -16.237 1.00 18.01 ? 230 SER A OG 1 ATOM 1796 N N . PHE A 1 231 ? -37.754 24.643 -15.527 1.00 14.15 ? 231 PHE A N 1 ATOM 1797 C CA . PHE A 1 231 ? -36.373 25.084 -15.880 1.00 13.42 ? 231 PHE A CA 1 ATOM 1798 C C . PHE A 1 231 ? -35.457 24.033 -15.309 1.00 13.65 ? 231 PHE A C 1 ATOM 1799 O O . PHE A 1 231 ? -35.910 23.149 -14.557 1.00 12.75 ? 231 PHE A O 1 ATOM 1800 C CB . PHE A 1 231 ? -36.047 26.493 -15.329 1.00 15.29 ? 231 PHE A CB 1 ATOM 1801 C CG . PHE A 1 231 ? -35.798 26.531 -13.854 1.00 16.62 ? 231 PHE A CG 1 ATOM 1802 C CD1 . PHE A 1 231 ? -34.494 26.633 -13.366 1.00 17.78 ? 231 PHE A CD1 1 ATOM 1803 C CD2 . PHE A 1 231 ? -36.865 26.434 -12.937 1.00 15.72 ? 231 PHE A CD2 1 ATOM 1804 C CE1 . PHE A 1 231 ? -34.242 26.670 -11.983 1.00 19.73 ? 231 PHE A CE1 1 ATOM 1805 C CE2 . PHE A 1 231 ? -36.619 26.488 -11.551 1.00 17.26 ? 231 PHE A CE2 1 ATOM 1806 C CZ . PHE A 1 231 ? -35.282 26.590 -11.074 1.00 18.27 ? 231 PHE A CZ 1 ATOM 1807 N N . GLY A 1 232 ? -34.167 24.098 -15.663 1.00 12.92 ? 232 GLY A N 1 ATOM 1808 C CA . GLY A 1 232 ? -33.287 23.105 -15.131 1.00 12.28 ? 232 GLY A CA 1 ATOM 1809 C C . GLY A 1 232 ? -31.933 23.774 -14.930 1.00 11.53 ? 232 GLY A C 1 ATOM 1810 O O . GLY A 1 232 ? -31.708 24.878 -15.383 1.00 12.11 ? 232 GLY A O 1 ATOM 1811 N N . VAL A 1 233 ? -31.091 23.116 -14.175 1.00 12.70 ? 233 VAL A N 1 ATOM 1812 C CA . VAL A 1 233 ? -29.766 23.670 -13.835 1.00 12.30 ? 233 VAL A CA 1 ATOM 1813 C C . VAL A 1 233 ? -28.737 22.556 -13.931 1.00 13.39 ? 233 VAL A C 1 ATOM 1814 O O . VAL A 1 233 ? -28.996 21.436 -13.495 1.00 13.11 ? 233 VAL A O 1 ATOM 1815 C CB . VAL A 1 233 ? -29.743 24.241 -12.392 1.00 13.04 ? 233 VAL A CB 1 ATOM 1816 C CG1 . VAL A 1 233 ? -28.308 24.741 -12.001 1.00 10.91 ? 233 VAL A CG1 1 ATOM 1817 C CG2 . VAL A 1 233 ? -30.718 25.424 -12.177 1.00 12.72 ? 233 VAL A CG2 1 ATOM 1818 N N . PHE A 1 234 ? -27.547 22.871 -14.468 1.00 12.17 ? 234 PHE A N 1 ATOM 1819 C CA . PHE A 1 234 ? -26.524 21.879 -14.552 1.00 12.84 ? 234 PHE A CA 1 ATOM 1820 C C . PHE A 1 234 ? -25.238 22.579 -14.094 1.00 12.85 ? 234 PHE A C 1 ATOM 1821 O O . PHE A 1 234 ? -25.011 23.728 -14.456 1.00 11.65 ? 234 PHE A O 1 ATOM 1822 C CB . PHE A 1 234 ? -26.379 21.412 -15.983 1.00 13.52 ? 234 PHE A CB 1 ATOM 1823 C CG . PHE A 1 234 ? -25.107 20.648 -16.242 1.00 12.46 ? 234 PHE A CG 1 ATOM 1824 C CD1 . PHE A 1 234 ? -24.879 19.410 -15.613 1.00 13.18 ? 234 PHE A CD1 1 ATOM 1825 C CD2 . PHE A 1 234 ? -24.207 21.117 -17.163 1.00 15.18 ? 234 PHE A CD2 1 ATOM 1826 C CE1 . PHE A 1 234 ? -23.725 18.683 -15.849 1.00 16.59 ? 234 PHE A CE1 1 ATOM 1827 C CE2 . PHE A 1 234 ? -23.012 20.376 -17.428 1.00 17.19 ? 234 PHE A CE2 1 ATOM 1828 C CZ . PHE A 1 234 ? -22.776 19.182 -16.740 1.00 13.46 ? 234 PHE A CZ 1 ATOM 1829 N N . LEU A 1 235 ? -24.471 21.895 -13.242 1.00 13.68 ? 235 LEU A N 1 ATOM 1830 C CA . LEU A 1 235 ? -23.140 22.360 -12.825 1.00 14.69 ? 235 LEU A CA 1 ATOM 1831 C C . LEU A 1 235 ? -22.088 21.499 -13.519 1.00 13.96 ? 235 LEU A C 1 ATOM 1832 O O . LEU A 1 235 ? -22.085 20.291 -13.327 1.00 15.08 ? 235 LEU A O 1 ATOM 1833 C CB . LEU A 1 235 ? -23.011 22.232 -11.302 1.00 14.85 ? 235 LEU A CB 1 ATOM 1834 C CG . LEU A 1 235 ? -21.596 22.473 -10.697 1.00 16.13 ? 235 LEU A CG 1 ATOM 1835 C CD1 . LEU A 1 235 ? -21.089 23.867 -11.020 1.00 15.32 ? 235 LEU A CD1 1 ATOM 1836 C CD2 . LEU A 1 235 ? -21.619 22.204 -9.193 1.00 17.03 ? 235 LEU A CD2 1 ATOM 1837 N N . MET A 1 236 ? -21.222 22.111 -14.336 1.00 13.39 ? 236 MET A N 1 ATOM 1838 C CA . MET A 1 236 ? -20.169 21.423 -15.049 1.00 15.18 ? 236 MET A CA 1 ATOM 1839 C C . MET A 1 236 ? -18.946 21.421 -14.109 1.00 15.26 ? 236 MET A C 1 ATOM 1840 O O . MET A 1 236 ? -18.123 22.343 -14.148 1.00 16.15 ? 236 MET A O 1 ATOM 1841 C CB . MET A 1 236 ? -19.766 22.204 -16.317 1.00 14.81 ? 236 MET A CB 1 ATOM 1842 C CG . MET A 1 236 ? -18.644 21.483 -17.127 1.00 18.22 ? 236 MET A CG 1 ATOM 1843 S SD . MET A 1 236 ? -19.062 19.904 -17.868 1.00 22.75 ? 236 MET A SD 1 ATOM 1844 C CE . MET A 1 236 ? -19.640 20.497 -19.482 1.00 22.11 ? 236 MET A CE 1 ATOM 1845 N N . ASN A 1 237 ? -18.869 20.398 -13.269 1.00 15.65 ? 237 ASN A N 1 ATOM 1846 C CA . ASN A 1 237 ? -17.823 20.269 -12.245 1.00 15.08 ? 237 ASN A CA 1 ATOM 1847 C C . ASN A 1 237 ? -17.726 18.782 -11.961 1.00 15.69 ? 237 ASN A C 1 ATOM 1848 O O . ASN A 1 237 ? -18.742 18.083 -11.781 1.00 13.81 ? 237 ASN A O 1 ATOM 1849 C CB . ASN A 1 237 ? -18.192 21.102 -10.982 1.00 13.33 ? 237 ASN A CB 1 ATOM 1850 C CG . ASN A 1 237 ? -17.099 21.061 -9.870 1.00 16.07 ? 237 ASN A CG 1 ATOM 1851 O OD1 . ASN A 1 237 ? -16.950 20.074 -9.177 1.00 16.08 ? 237 ASN A OD1 1 ATOM 1852 N ND2 . ASN A 1 237 ? -16.471 22.183 -9.632 1.00 14.25 ? 237 ASN A ND2 1 ATOM 1853 N N . SER A 1 238 ? -16.506 18.272 -11.981 1.00 14.93 ? 238 SER A N 1 ATOM 1854 C CA . SER A 1 238 ? -16.285 16.864 -11.725 1.00 16.82 ? 238 SER A CA 1 ATOM 1855 C C . SER A 1 238 ? -15.554 16.492 -10.390 1.00 17.50 ? 238 SER A C 1 ATOM 1856 O O . SER A 1 238 ? -15.084 15.364 -10.258 1.00 19.08 ? 238 SER A O 1 ATOM 1857 C CB . SER A 1 238 ? -15.490 16.306 -12.897 1.00 17.91 ? 238 SER A CB 1 ATOM 1858 O OG . SER A 1 238 ? -14.276 17.010 -13.006 1.00 16.26 ? 238 SER A OG 1 ATOM 1859 N N . ASN A 1 239 ? -15.359 17.454 -9.490 1.00 17.30 ? 239 ASN A N 1 ATOM 1860 C CA . ASN A 1 239 ? -14.822 17.207 -8.141 1.00 17.26 ? 239 ASN A CA 1 ATOM 1861 C C . ASN A 1 239 ? -15.884 16.580 -7.244 1.00 17.13 ? 239 ASN A C 1 ATOM 1862 O O . ASN A 1 239 ? -17.097 16.612 -7.585 1.00 16.11 ? 239 ASN A O 1 ATOM 1863 C CB . ASN A 1 239 ? -14.289 18.513 -7.542 1.00 16.35 ? 239 ASN A CB 1 ATOM 1864 C CG . ASN A 1 239 ? -13.046 18.997 -8.271 1.00 18.06 ? 239 ASN A CG 1 ATOM 1865 O OD1 . ASN A 1 239 ? -11.914 18.665 -7.879 1.00 21.01 ? 239 ASN A OD1 1 ATOM 1866 N ND2 . ASN A 1 239 ? -13.235 19.765 -9.329 1.00 14.42 ? 239 ASN A ND2 1 ATOM 1867 N N . ALA A 1 240 ? -15.453 15.957 -6.144 1.00 15.34 ? 240 ALA A N 1 ATOM 1868 C CA . ALA A 1 240 ? -16.419 15.472 -5.142 1.00 16.66 ? 240 ALA A CA 1 ATOM 1869 C C . ALA A 1 240 ? -17.272 16.619 -4.700 1.00 16.41 ? 240 ALA A C 1 ATOM 1870 O O . ALA A 1 240 ? -16.791 17.726 -4.505 1.00 15.75 ? 240 ALA A O 1 ATOM 1871 C CB . ALA A 1 240 ? -15.716 14.851 -3.915 1.00 17.10 ? 240 ALA A CB 1 ATOM 1872 N N . MET A 1 241 ? -18.563 16.357 -4.561 1.00 16.35 ? 241 MET A N 1 ATOM 1873 C CA . MET A 1 241 ? -19.424 17.415 -4.159 1.00 17.05 ? 241 MET A CA 1 ATOM 1874 C C . MET A 1 241 ? -20.581 16.829 -3.395 1.00 15.86 ? 241 MET A C 1 ATOM 1875 O O . MET A 1 241 ? -20.744 15.611 -3.330 1.00 15.20 ? 241 MET A O 1 ATOM 1876 C CB . MET A 1 241 ? -19.910 18.184 -5.389 1.00 17.52 ? 241 MET A CB 1 ATOM 1877 C CG . MET A 1 241 ? -20.841 17.402 -6.255 1.00 18.70 ? 241 MET A CG 1 ATOM 1878 S SD . MET A 1 241 ? -21.587 18.520 -7.461 1.00 22.43 ? 241 MET A SD 1 ATOM 1879 C CE . MET A 1 241 ? -20.140 18.684 -8.514 1.00 17.18 ? 241 MET A CE 1 ATOM 1880 N N . GLU A 1 242 ? -21.380 17.703 -2.812 1.00 16.19 ? 242 GLU A N 1 ATOM 1881 C CA . GLU A 1 242 ? -22.673 17.282 -2.330 1.00 16.24 ? 242 GLU A CA 1 ATOM 1882 C C . GLU A 1 242 ? -23.720 18.350 -2.602 1.00 16.05 ? 242 GLU A C 1 ATOM 1883 O O . GLU A 1 242 ? -23.416 19.522 -2.824 1.00 16.93 ? 242 GLU A O 1 ATOM 1884 C CB . GLU A 1 242 ? -22.632 16.880 -0.860 1.00 16.48 ? 242 GLU A CB 1 ATOM 1885 C CG . GLU A 1 242 ? -22.300 17.986 0.105 1.00 18.85 ? 242 GLU A CG 1 ATOM 1886 C CD . GLU A 1 242 ? -21.838 17.445 1.456 1.00 26.33 ? 242 GLU A CD 1 ATOM 1887 O OE1 . GLU A 1 242 ? -21.619 16.210 1.588 1.00 25.61 ? 242 GLU A OE1 1 ATOM 1888 O OE2 . GLU A 1 242 ? -21.673 18.265 2.391 1.00 27.60 ? 242 GLU A OE2 1 ATOM 1889 N N . VAL A 1 243 ? -24.974 17.941 -2.602 1.00 16.77 ? 243 VAL A N 1 ATOM 1890 C CA . VAL A 1 243 ? -25.999 18.875 -2.957 1.00 16.33 ? 243 VAL A CA 1 ATOM 1891 C C . VAL A 1 243 ? -26.950 18.849 -1.801 1.00 16.85 ? 243 VAL A C 1 ATOM 1892 O O . VAL A 1 243 ? -27.346 17.767 -1.363 1.00 16.50 ? 243 VAL A O 1 ATOM 1893 C CB . VAL A 1 243 ? -26.702 18.460 -4.294 1.00 17.36 ? 243 VAL A CB 1 ATOM 1894 C CG1 . VAL A 1 243 ? -27.845 19.365 -4.578 1.00 16.81 ? 243 VAL A CG1 1 ATOM 1895 C CG2 . VAL A 1 243 ? -25.720 18.536 -5.464 1.00 17.65 ? 243 VAL A CG2 1 ATOM 1896 N N . VAL A 1 244 ? -27.308 20.034 -1.297 1.00 15.68 ? 244 VAL A N 1 ATOM 1897 C CA . VAL A 1 244 ? -28.087 20.137 -0.082 1.00 15.51 ? 244 VAL A CA 1 ATOM 1898 C C . VAL A 1 244 ? -29.445 20.695 -0.450 1.00 14.70 ? 244 VAL A C 1 ATOM 1899 O O . VAL A 1 244 ? -29.543 21.752 -1.028 1.00 14.67 ? 244 VAL A O 1 ATOM 1900 C CB . VAL A 1 244 ? -27.430 21.068 0.912 1.00 15.53 ? 244 VAL A CB 1 ATOM 1901 C CG1 . VAL A 1 244 ? -28.276 21.173 2.223 1.00 15.80 ? 244 VAL A CG1 1 ATOM 1902 C CG2 . VAL A 1 244 ? -26.015 20.570 1.184 1.00 17.95 ? 244 VAL A CG2 1 ATOM 1903 N N . LEU A 1 245 ? -30.476 19.989 -0.070 1.00 15.64 ? 245 LEU A N 1 ATOM 1904 C CA . LEU A 1 245 ? -31.829 20.413 -0.428 1.00 16.01 ? 245 LEU A CA 1 ATOM 1905 C C . LEU A 1 245 ? -32.500 20.828 0.834 1.00 16.85 ? 245 LEU A C 1 ATOM 1906 O O . LEU A 1 245 ? -32.417 20.113 1.837 1.00 18.44 ? 245 LEU A O 1 ATOM 1907 C CB . LEU A 1 245 ? -32.587 19.240 -1.047 1.00 16.65 ? 245 LEU A CB 1 ATOM 1908 C CG . LEU A 1 245 ? -31.925 18.557 -2.262 1.00 17.41 ? 245 LEU A CG 1 ATOM 1909 C CD1 . LEU A 1 245 ? -32.835 17.423 -2.686 1.00 21.49 ? 245 LEU A CD1 1 ATOM 1910 C CD2 . LEU A 1 245 ? -31.805 19.522 -3.365 1.00 19.18 ? 245 LEU A CD2 1 ATOM 1911 N N . GLN A 1 246 ? -33.187 21.963 0.813 1.00 16.88 ? 246 GLN A N 1 ATOM 1912 C CA . GLN A 1 246 ? -33.917 22.394 2.021 1.00 16.82 ? 246 GLN A CA 1 ATOM 1913 C C . GLN A 1 246 ? -35.278 22.997 1.694 1.00 17.35 ? 246 GLN A C 1 ATOM 1914 O O . GLN A 1 246 ? -35.495 23.385 0.538 1.00 17.30 ? 246 GLN A O 1 ATOM 1915 C CB . GLN A 1 246 ? -33.067 23.355 2.810 1.00 16.26 ? 246 GLN A CB 1 ATOM 1916 C CG . GLN A 1 246 ? -32.897 24.728 2.205 1.00 15.16 ? 246 GLN A CG 1 ATOM 1917 C CD . GLN A 1 246 ? -31.798 25.458 2.956 1.00 17.75 ? 246 GLN A CD 1 ATOM 1918 O OE1 . GLN A 1 246 ? -30.621 25.120 2.822 1.00 17.21 ? 246 GLN A OE1 1 ATOM 1919 N NE2 . GLN A 1 246 ? -32.176 26.461 3.756 1.00 15.12 ? 246 GLN A NE2 1 ATOM 1920 N N . PRO A 1 247 ? -36.197 23.079 2.692 1.00 18.43 ? 247 PRO A N 1 ATOM 1921 C CA . PRO A 1 247 ? -37.587 23.415 2.385 1.00 19.17 ? 247 PRO A CA 1 ATOM 1922 C C . PRO A 1 247 ? -37.929 24.866 2.103 1.00 20.01 ? 247 PRO A C 1 ATOM 1923 O O . PRO A 1 247 ? -39.101 25.156 1.918 1.00 22.21 ? 247 PRO A O 1 ATOM 1924 C CB . PRO A 1 247 ? -38.364 22.967 3.646 1.00 19.28 ? 247 PRO A CB 1 ATOM 1925 C CG . PRO A 1 247 ? -37.374 22.358 4.556 1.00 20.54 ? 247 PRO A CG 1 ATOM 1926 C CD . PRO A 1 247 ? -36.022 22.798 4.118 1.00 19.53 ? 247 PRO A CD 1 ATOM 1927 N N . ALA A 1 248 ? -36.957 25.768 2.066 1.00 20.87 ? 248 ALA A N 1 ATOM 1928 C CA . ALA A 1 248 ? -37.168 27.167 1.641 1.00 20.58 ? 248 ALA A CA 1 ATOM 1929 C C . ALA A 1 248 ? -38.201 27.382 0.506 1.00 22.49 ? 248 ALA A C 1 ATOM 1930 O O . ALA A 1 248 ? -39.077 28.263 0.654 1.00 21.08 ? 248 ALA A O 1 ATOM 1931 C CB . ALA A 1 248 ? -35.829 27.820 1.277 1.00 20.93 ? 248 ALA A CB 1 ATOM 1932 N N . PRO A 1 249 ? -38.116 26.594 -0.651 1.00 20.80 ? 249 PRO A N 1 ATOM 1933 C CA . PRO A 1 249 ? -37.164 25.559 -1.084 1.00 19.56 ? 249 PRO A CA 1 ATOM 1934 C C . PRO A 1 249 ? -35.881 26.125 -1.664 1.00 18.72 ? 249 PRO A C 1 ATOM 1935 O O . PRO A 1 249 ? -35.886 27.201 -2.273 1.00 18.01 ? 249 PRO A O 1 ATOM 1936 C CB . PRO A 1 249 ? -37.924 24.811 -2.183 1.00 19.85 ? 249 PRO A CB 1 ATOM 1937 C CG . PRO A 1 249 ? -38.912 25.751 -2.696 1.00 20.39 ? 249 PRO A CG 1 ATOM 1938 C CD . PRO A 1 249 ? -39.214 26.762 -1.623 1.00 21.18 ? 249 PRO A CD 1 ATOM 1939 N N . ALA A 1 250 ? -34.794 25.389 -1.508 1.00 17.27 ? 250 ALA A N 1 ATOM 1940 C CA . ALA A 1 250 ? -33.525 25.879 -2.032 1.00 16.58 ? 250 ALA A CA 1 ATOM 1941 C C . ALA A 1 250 ? -32.602 24.720 -2.214 1.00 16.06 ? 250 ALA A C 1 ATOM 1942 O O . ALA A 1 250 ? -32.786 23.666 -1.595 1.00 14.57 ? 250 ALA A O 1 ATOM 1943 C CB . ALA A 1 250 ? -32.944 26.862 -1.070 1.00 16.33 ? 250 ALA A CB 1 ATOM 1944 N N . ILE A 1 251 ? -31.581 24.912 -3.049 1.00 15.88 ? 251 ILE A N 1 ATOM 1945 C CA . ILE A 1 251 ? -30.593 23.889 -3.249 1.00 16.90 ? 251 ILE A CA 1 ATOM 1946 C C . ILE A 1 251 ? -29.245 24.555 -3.154 1.00 16.36 ? 251 ILE A C 1 ATOM 1947 O O . ILE A 1 251 ? -29.099 25.677 -3.603 1.00 16.07 ? 251 ILE A O 1 ATOM 1948 C CB . ILE A 1 251 ? -30.781 23.142 -4.612 1.00 17.14 ? 251 ILE A CB 1 ATOM 1949 C CG1 . ILE A 1 251 ? -29.573 22.274 -4.973 1.00 19.68 ? 251 ILE A CG1 1 ATOM 1950 C CG2 . ILE A 1 251 ? -31.082 24.122 -5.755 1.00 21.48 ? 251 ILE A CG2 1 ATOM 1951 C CD1 . ILE A 1 251 ? -29.904 21.192 -6.046 1.00 20.56 ? 251 ILE A CD1 1 ATOM 1952 N N . THR A 1 252 ? -28.290 23.866 -2.542 1.00 15.80 ? 252 THR A N 1 ATOM 1953 C CA . THR A 1 252 ? -26.938 24.365 -2.413 1.00 17.20 ? 252 THR A CA 1 ATOM 1954 C C . THR A 1 252 ? -26.009 23.332 -3.033 1.00 17.12 ? 252 THR A C 1 ATOM 1955 O O . THR A 1 252 ? -26.171 22.133 -2.805 1.00 16.50 ? 252 THR A O 1 ATOM 1956 C CB . THR A 1 252 ? -26.604 24.566 -0.932 1.00 17.66 ? 252 THR A CB 1 ATOM 1957 O OG1 . THR A 1 252 ? -27.468 25.588 -0.400 1.00 17.39 ? 252 THR A OG1 1 ATOM 1958 C CG2 . THR A 1 252 ? -25.154 25.001 -0.739 1.00 18.22 ? 252 THR A CG2 1 ATOM 1959 N N . TYR A 1 253 ? -25.073 23.797 -3.845 1.00 17.33 ? 253 TYR A N 1 ATOM 1960 C CA . TYR A 1 253 ? -24.029 22.949 -4.400 1.00 18.15 ? 253 TYR A CA 1 ATOM 1961 C C . TYR A 1 253 ? -22.773 23.276 -3.626 1.00 18.33 ? 253 TYR A C 1 ATOM 1962 O O . TYR A 1 253 ? -22.465 24.446 -3.443 1.00 17.41 ? 253 TYR A O 1 ATOM 1963 C CB . TYR A 1 253 ? -23.772 23.306 -5.858 1.00 20.12 ? 253 TYR A CB 1 ATOM 1964 C CG . TYR A 1 253 ? -24.803 22.803 -6.859 1.00 21.74 ? 253 TYR A CG 1 ATOM 1965 C CD1 . TYR A 1 253 ? -24.641 21.559 -7.459 1.00 24.60 ? 253 TYR A CD1 1 ATOM 1966 C CD2 . TYR A 1 253 ? -25.904 23.572 -7.214 1.00 24.34 ? 253 TYR A CD2 1 ATOM 1967 C CE1 . TYR A 1 253 ? -25.569 21.068 -8.400 1.00 26.10 ? 253 TYR A CE1 1 ATOM 1968 C CE2 . TYR A 1 253 ? -26.854 23.093 -8.161 1.00 23.29 ? 253 TYR A CE2 1 ATOM 1969 C CZ . TYR A 1 253 ? -26.663 21.844 -8.745 1.00 25.87 ? 253 TYR A CZ 1 ATOM 1970 O OH . TYR A 1 253 ? -27.560 21.348 -9.694 1.00 25.99 ? 253 TYR A OH 1 ATOM 1971 N N . ARG A 1 254 ? -22.035 22.244 -3.232 1.00 18.14 ? 254 ARG A N 1 ATOM 1972 C CA . ARG A 1 254 ? -20.849 22.377 -2.385 1.00 18.93 ? 254 ARG A CA 1 ATOM 1973 C C . ARG A 1 254 ? -19.833 21.441 -3.004 1.00 18.31 ? 254 ARG A C 1 ATOM 1974 O O . ARG A 1 254 ? -20.004 20.247 -2.902 1.00 19.86 ? 254 ARG A O 1 ATOM 1975 C CB . ARG A 1 254 ? -21.263 21.907 -0.981 1.00 19.75 ? 254 ARG A CB 1 ATOM 1976 C CG . ARG A 1 254 ? -20.310 22.192 0.203 1.00 21.04 ? 254 ARG A CG 1 ATOM 1977 C CD . ARG A 1 254 ? -20.930 21.600 1.462 1.00 20.45 ? 254 ARG A CD 1 ATOM 1978 N NE . ARG A 1 254 ? -22.033 22.395 2.038 1.00 20.41 ? 254 ARG A NE 1 ATOM 1979 C CZ . ARG A 1 254 ? -22.987 21.900 2.822 1.00 22.56 ? 254 ARG A CZ 1 ATOM 1980 N NH1 . ARG A 1 254 ? -23.036 20.601 3.094 1.00 23.83 ? 254 ARG A NH1 1 ATOM 1981 N NH2 . ARG A 1 254 ? -23.902 22.694 3.349 1.00 24.28 ? 254 ARG A NH2 1 ATOM 1982 N N . THR A 1 255 ? -18.788 21.951 -3.659 1.00 17.54 ? 255 THR A N 1 ATOM 1983 C CA . THR A 1 255 ? -17.810 21.095 -4.325 1.00 17.33 ? 255 THR A CA 1 ATOM 1984 C C . THR A 1 255 ? -16.395 21.392 -3.761 1.00 17.40 ? 255 THR A C 1 ATOM 1985 O O . THR A 1 255 ? -16.172 22.442 -3.186 1.00 17.46 ? 255 THR A O 1 ATOM 1986 C CB . THR A 1 255 ? -17.845 21.251 -5.861 1.00 17.59 ? 255 THR A CB 1 ATOM 1987 O OG1 . THR A 1 255 ? -16.884 20.375 -6.474 1.00 20.52 ? 255 THR A OG1 1 ATOM 1988 C CG2 . THR A 1 255 ? -17.561 22.672 -6.296 1.00 19.15 ? 255 THR A CG2 1 ATOM 1989 N N . ILE A 1 256 ? -15.460 20.475 -3.945 1.00 17.19 ? 256 ILE A N 1 ATOM 1990 C CA . ILE A 1 256 ? -14.134 20.627 -3.301 1.00 16.60 ? 256 ILE A CA 1 ATOM 1991 C C . ILE A 1 256 ? -13.031 20.898 -4.309 1.00 16.82 ? 256 ILE A C 1 ATOM 1992 O O . ILE A 1 256 ? -11.811 20.753 -4.020 1.00 17.23 ? 256 ILE A O 1 ATOM 1993 C CB . ILE A 1 256 ? -13.792 19.441 -2.348 1.00 16.94 ? 256 ILE A CB 1 ATOM 1994 C CG1 . ILE A 1 256 ? -13.692 18.119 -3.115 1.00 16.53 ? 256 ILE A CG1 1 ATOM 1995 C CG2 . ILE A 1 256 ? -14.831 19.308 -1.258 1.00 16.19 ? 256 ILE A CG2 1 ATOM 1996 C CD1 . ILE A 1 256 ? -13.158 16.989 -2.261 1.00 16.99 ? 256 ILE A CD1 1 ATOM 1997 N N . GLY A 1 257 ? -13.435 21.328 -5.500 1.00 15.91 ? 257 GLY A N 1 ATOM 1998 C CA . GLY A 1 257 ? -12.432 21.880 -6.400 1.00 14.89 ? 257 GLY A CA 1 ATOM 1999 C C . GLY A 1 257 ? -13.044 22.425 -7.650 1.00 15.13 ? 257 GLY A C 1 ATOM 2000 O O . GLY A 1 257 ? -14.280 22.580 -7.751 1.00 14.56 ? 257 GLY A O 1 ATOM 2001 N N . GLY A 1 258 ? -12.172 22.688 -8.609 1.00 13.45 ? 258 GLY A N 1 ATOM 2002 C CA . GLY A 1 258 ? -12.557 23.231 -9.912 1.00 13.70 ? 258 GLY A CA 1 ATOM 2003 C C . GLY A 1 258 ? -13.189 24.582 -9.807 1.00 13.63 ? 258 GLY A C 1 ATOM 2004 O O . GLY A 1 258 ? -12.830 25.417 -8.949 1.00 13.90 ? 258 GLY A O 1 ATOM 2005 N N . ILE A 1 259 ? -14.207 24.802 -10.643 1.00 15.18 ? 259 ILE A N 1 ATOM 2006 C CA . ILE A 1 259 ? -14.839 26.110 -10.699 1.00 16.08 ? 259 ILE A CA 1 ATOM 2007 C C . ILE A 1 259 ? -16.363 25.938 -10.690 1.00 16.79 ? 259 ILE A C 1 ATOM 2008 O O . ILE A 1 259 ? -16.878 24.840 -10.937 1.00 16.42 ? 259 ILE A O 1 ATOM 2009 C CB . ILE A 1 259 ? -14.396 26.941 -11.985 1.00 15.91 ? 259 ILE A CB 1 ATOM 2010 C CG1 . ILE A 1 259 ? -14.827 26.249 -13.288 1.00 16.08 ? 259 ILE A CG1 1 ATOM 2011 C CG2 . ILE A 1 259 ? -12.865 27.134 -12.035 1.00 15.26 ? 259 ILE A CG2 1 ATOM 2012 C CD1 . ILE A 1 259 ? -14.977 27.193 -14.523 1.00 17.06 ? 259 ILE A CD1 1 ATOM 2013 N N . LEU A 1 260 ? -17.058 27.032 -10.431 1.00 16.92 ? 260 LEU A N 1 ATOM 2014 C CA . LEU A 1 260 ? -18.521 26.983 -10.464 1.00 17.44 ? 260 LEU A CA 1 ATOM 2015 C C . LEU A 1 260 ? -18.904 27.377 -11.884 1.00 18.34 ? 260 LEU A C 1 ATOM 2016 O O . LEU A 1 260 ? -18.770 28.536 -12.256 1.00 19.85 ? 260 LEU A O 1 ATOM 2017 C CB . LEU A 1 260 ? -19.110 27.913 -9.411 1.00 16.45 ? 260 LEU A CB 1 ATOM 2018 C CG . LEU A 1 260 ? -18.884 27.472 -7.968 1.00 17.63 ? 260 LEU A CG 1 ATOM 2019 C CD1 . LEU A 1 260 ? -19.438 28.491 -6.972 1.00 21.04 ? 260 LEU A CD1 1 ATOM 2020 C CD2 . LEU A 1 260 ? -19.463 26.035 -7.676 1.00 17.48 ? 260 LEU A CD2 1 ATOM 2021 N N . ASP A 1 261 ? -19.321 26.394 -12.676 1.00 18.55 ? 261 ASP A N 1 ATOM 2022 C CA . ASP A 1 261 ? -19.598 26.593 -14.091 1.00 18.17 ? 261 ASP A CA 1 ATOM 2023 C C . ASP A 1 261 ? -21.034 26.102 -14.282 1.00 18.58 ? 261 ASP A C 1 ATOM 2024 O O . ASP A 1 261 ? -21.244 24.896 -14.340 1.00 17.23 ? 261 ASP A O 1 ATOM 2025 C CB . ASP A 1 261 ? -18.638 25.737 -14.924 1.00 19.32 ? 261 ASP A CB 1 ATOM 2026 C CG . ASP A 1 261 ? -18.819 25.945 -16.434 1.00 23.03 ? 261 ASP A CG 1 ATOM 2027 O OD1 . ASP A 1 261 ? -19.764 26.662 -16.812 1.00 25.59 ? 261 ASP A OD1 1 ATOM 2028 O OD2 . ASP A 1 261 ? -18.049 25.405 -17.253 1.00 21.28 ? 261 ASP A OD2 1 ATOM 2029 N N . PHE A 1 262 ? -21.984 27.048 -14.368 1.00 16.66 ? 262 PHE A N 1 ATOM 2030 C CA . PHE A 1 262 ? -23.434 26.767 -14.281 1.00 16.37 ? 262 PHE A CA 1 ATOM 2031 C C . PHE A 1 262 ? -24.134 27.039 -15.593 1.00 15.23 ? 262 PHE A C 1 ATOM 2032 O O . PHE A 1 262 ? -23.827 28.044 -16.273 1.00 15.46 ? 262 PHE A O 1 ATOM 2033 C CB . PHE A 1 262 ? -24.098 27.644 -13.206 1.00 16.37 ? 262 PHE A CB 1 ATOM 2034 C CG . PHE A 1 262 ? -23.973 27.104 -11.785 1.00 17.81 ? 262 PHE A CG 1 ATOM 2035 C CD1 . PHE A 1 262 ? -24.745 26.012 -11.356 1.00 16.67 ? 262 PHE A CD1 1 ATOM 2036 C CD2 . PHE A 1 262 ? -23.067 27.686 -10.871 1.00 16.16 ? 262 PHE A CD2 1 ATOM 2037 C CE1 . PHE A 1 262 ? -24.640 25.499 -10.039 1.00 18.54 ? 262 PHE A CE1 1 ATOM 2038 C CE2 . PHE A 1 262 ? -22.974 27.175 -9.537 1.00 15.52 ? 262 PHE A CE2 1 ATOM 2039 C CZ . PHE A 1 262 ? -23.741 26.079 -9.137 1.00 20.03 ? 262 PHE A CZ 1 ATOM 2040 N N . TYR A 1 263 ? -25.115 26.206 -15.911 1.00 14.72 ? 263 TYR A N 1 ATOM 2041 C CA . TYR A 1 263 ? -26.023 26.486 -17.046 1.00 13.84 ? 263 TYR A CA 1 ATOM 2042 C C . TYR A 1 263 ? -27.426 26.464 -16.490 1.00 14.29 ? 263 TYR A C 1 ATOM 2043 O O . TYR A 1 263 ? -27.723 25.679 -15.588 1.00 13.98 ? 263 TYR A O 1 ATOM 2044 C CB . TYR A 1 263 ? -25.906 25.391 -18.104 1.00 14.09 ? 263 TYR A CB 1 ATOM 2045 C CG . TYR A 1 263 ? -24.543 25.379 -18.808 1.00 15.60 ? 263 TYR A CG 1 ATOM 2046 C CD1 . TYR A 1 263 ? -24.374 26.005 -20.049 1.00 17.64 ? 263 TYR A CD1 1 ATOM 2047 C CD2 . TYR A 1 263 ? -23.455 24.747 -18.225 1.00 16.92 ? 263 TYR A CD2 1 ATOM 2048 C CE1 . TYR A 1 263 ? -23.157 25.968 -20.732 1.00 16.60 ? 263 TYR A CE1 1 ATOM 2049 C CE2 . TYR A 1 263 ? -22.210 24.729 -18.882 1.00 16.66 ? 263 TYR A CE2 1 ATOM 2050 C CZ . TYR A 1 263 ? -22.094 25.336 -20.139 1.00 17.62 ? 263 TYR A CZ 1 ATOM 2051 O OH . TYR A 1 263 ? -20.924 25.376 -20.837 1.00 15.36 ? 263 TYR A OH 1 ATOM 2052 N N . VAL A 1 264 ? -28.267 27.344 -17.008 1.00 13.18 ? 264 VAL A N 1 ATOM 2053 C CA . VAL A 1 264 ? -29.641 27.430 -16.544 1.00 13.49 ? 264 VAL A CA 1 ATOM 2054 C C . VAL A 1 264 ? -30.468 27.336 -17.843 1.00 13.86 ? 264 VAL A C 1 ATOM 2055 O O . VAL A 1 264 ? -30.139 28.001 -18.840 1.00 14.89 ? 264 VAL A O 1 ATOM 2056 C CB . VAL A 1 264 ? -29.957 28.740 -15.752 1.00 12.55 ? 264 VAL A CB 1 ATOM 2057 C CG1 . VAL A 1 264 ? -31.513 28.842 -15.378 1.00 13.53 ? 264 VAL A CG1 1 ATOM 2058 C CG2 . VAL A 1 264 ? -29.155 28.877 -14.443 1.00 13.84 ? 264 VAL A CG2 1 ATOM 2059 N N . PHE A 1 265 ? -31.523 26.509 -17.832 1.00 13.83 ? 265 PHE A N 1 ATOM 2060 C CA . PHE A 1 265 ? -32.258 26.163 -19.060 1.00 13.83 ? 265 PHE A CA 1 ATOM 2061 C C . PHE A 1 265 ? -33.709 26.457 -18.786 1.00 13.41 ? 265 PHE A C 1 ATOM 2062 O O . PHE A 1 265 ? -34.163 26.068 -17.727 1.00 14.51 ? 265 PHE A O 1 ATOM 2063 C CB . PHE A 1 265 ? -32.163 24.636 -19.343 1.00 13.74 ? 265 PHE A CB 1 ATOM 2064 C CG . PHE A 1 265 ? -30.739 24.083 -19.401 1.00 15.32 ? 265 PHE A CG 1 ATOM 2065 C CD1 . PHE A 1 265 ? -29.982 24.222 -20.543 1.00 15.53 ? 265 PHE A CD1 1 ATOM 2066 C CD2 . PHE A 1 265 ? -30.219 23.373 -18.313 1.00 17.10 ? 265 PHE A CD2 1 ATOM 2067 C CE1 . PHE A 1 265 ? -28.643 23.725 -20.610 1.00 17.01 ? 265 PHE A CE1 1 ATOM 2068 C CE2 . PHE A 1 265 ? -28.877 22.868 -18.363 1.00 18.23 ? 265 PHE A CE2 1 ATOM 2069 C CZ . PHE A 1 265 ? -28.114 23.042 -19.532 1.00 16.39 ? 265 PHE A CZ 1 ATOM 2070 N N . LEU A 1 266 ? -34.445 27.057 -19.736 1.00 13.83 ? 266 LEU A N 1 ATOM 2071 C CA . LEU A 1 266 ? -35.880 27.298 -19.488 1.00 14.70 ? 266 LEU A CA 1 ATOM 2072 C C . LEU A 1 266 ? -36.648 26.564 -20.550 1.00 15.04 ? 266 LEU A C 1 ATOM 2073 O O . LEU A 1 266 ? -36.203 26.488 -21.679 1.00 15.79 ? 266 LEU A O 1 ATOM 2074 C CB . LEU A 1 266 ? -36.215 28.801 -19.602 1.00 13.97 ? 266 LEU A CB 1 ATOM 2075 C CG . LEU A 1 266 ? -35.904 29.670 -18.378 1.00 13.55 ? 266 LEU A CG 1 ATOM 2076 C CD1 . LEU A 1 266 ? -34.387 29.989 -18.271 1.00 17.73 ? 266 LEU A CD1 1 ATOM 2077 C CD2 . LEU A 1 266 ? -36.707 30.971 -18.527 1.00 15.27 ? 266 LEU A CD2 1 ATOM 2078 N N . GLY A 1 267 ? -37.823 26.056 -20.217 1.00 15.58 ? 267 GLY A N 1 ATOM 2079 C CA . GLY A 1 267 ? -38.672 25.479 -21.251 1.00 15.28 ? 267 GLY A CA 1 ATOM 2080 C C . GLY A 1 267 ? -40.113 25.708 -20.899 1.00 15.51 ? 267 GLY A C 1 ATOM 2081 O O . GLY A 1 267 ? -40.450 26.092 -19.758 1.00 15.28 ? 267 GLY A O 1 ATOM 2082 N N . ASN A 1 268 ? -40.978 25.484 -21.884 1.00 16.06 ? 268 ASN A N 1 ATOM 2083 C CA . ASN A 1 268 ? -42.392 25.615 -21.636 1.00 17.12 ? 268 ASN A CA 1 ATOM 2084 C C . ASN A 1 268 ? -43.008 24.392 -21.014 1.00 17.64 ? 268 ASN A C 1 ATOM 2085 O O . ASN A 1 268 ? -44.155 24.438 -20.557 1.00 16.89 ? 268 ASN A O 1 ATOM 2086 C CB . ASN A 1 268 ? -43.112 25.962 -22.938 1.00 17.60 ? 268 ASN A CB 1 ATOM 2087 C CG . ASN A 1 268 ? -42.777 27.354 -23.390 1.00 20.94 ? 268 ASN A CG 1 ATOM 2088 O OD1 . ASN A 1 268 ? -42.435 28.205 -22.570 1.00 24.51 ? 268 ASN A OD1 1 ATOM 2089 N ND2 . ASN A 1 268 ? -42.863 27.601 -24.691 1.00 22.67 ? 268 ASN A ND2 1 ATOM 2090 N N . THR A 1 269 ? -42.254 23.290 -20.999 1.00 17.07 ? 269 THR A N 1 ATOM 2091 C CA . THR A 1 269 ? -42.734 22.009 -20.466 1.00 16.62 ? 269 THR A CA 1 ATOM 2092 C C . THR A 1 269 ? -41.500 21.304 -19.891 1.00 15.44 ? 269 THR A C 1 ATOM 2093 O O . THR A 1 269 ? -40.389 21.651 -20.269 1.00 15.72 ? 269 THR A O 1 ATOM 2094 C CB . THR A 1 269 ? -43.283 21.058 -21.589 1.00 15.08 ? 269 THR A CB 1 ATOM 2095 O OG1 . THR A 1 269 ? -42.237 20.783 -22.542 1.00 17.19 ? 269 THR A OG1 1 ATOM 2096 C CG2 . THR A 1 269 ? -44.490 21.640 -22.322 1.00 17.43 ? 269 THR A CG2 1 ATOM 2097 N N . PRO A 1 270 ? -41.695 20.284 -19.029 1.00 15.41 ? 270 PRO A N 1 ATOM 2098 C CA . PRO A 1 270 ? -40.533 19.501 -18.578 1.00 14.46 ? 270 PRO A CA 1 ATOM 2099 C C . PRO A 1 270 ? -39.722 18.881 -19.718 1.00 15.34 ? 270 PRO A C 1 ATOM 2100 O O . PRO A 1 270 ? -38.464 18.932 -19.683 1.00 14.55 ? 270 PRO A O 1 ATOM 2101 C CB . PRO A 1 270 ? -41.165 18.415 -17.712 1.00 14.35 ? 270 PRO A CB 1 ATOM 2102 C CG . PRO A 1 270 ? -42.416 19.142 -17.112 1.00 14.36 ? 270 PRO A CG 1 ATOM 2103 C CD . PRO A 1 270 ? -42.936 19.855 -18.349 1.00 14.23 ? 270 PRO A CD 1 ATOM 2104 N N . GLU A 1 271 ? -40.398 18.355 -20.743 1.00 15.02 ? 271 GLU A N 1 ATOM 2105 C CA . GLU A 1 271 ? -39.652 17.788 -21.867 1.00 15.80 ? 271 GLU A CA 1 ATOM 2106 C C . GLU A 1 271 ? -38.744 18.805 -22.568 1.00 15.86 ? 271 GLU A C 1 ATOM 2107 O O . GLU A 1 271 ? -37.636 18.450 -23.006 1.00 14.96 ? 271 GLU A O 1 ATOM 2108 C CB . GLU A 1 271 ? -40.586 17.132 -22.900 1.00 16.12 ? 271 GLU A CB 1 ATOM 2109 C CG . GLU A 1 271 ? -41.181 15.825 -22.454 1.00 19.93 ? 271 GLU A CG 1 ATOM 2110 C CD . GLU A 1 271 ? -40.143 14.709 -22.437 1.00 22.65 ? 271 GLU A CD 1 ATOM 2111 O OE1 . GLU A 1 271 ? -39.597 14.339 -23.535 1.00 22.09 ? 271 GLU A OE1 1 ATOM 2112 O OE2 . GLU A 1 271 ? -39.865 14.219 -21.317 1.00 22.87 ? 271 GLU A OE2 1 ATOM 2113 N N . GLN A 1 272 ? -39.219 20.050 -22.713 1.00 15.20 ? 272 GLN A N 1 ATOM 2114 C CA . GLN A 1 272 ? -38.386 21.083 -23.352 1.00 16.34 ? 272 GLN A CA 1 ATOM 2115 C C . GLN A 1 272 ? -37.104 21.397 -22.551 1.00 15.36 ? 272 GLN A C 1 ATOM 2116 O O . GLN A 1 272 ? -36.059 21.642 -23.145 1.00 16.14 ? 272 GLN A O 1 ATOM 2117 C CB . GLN A 1 272 ? -39.175 22.340 -23.589 1.00 15.00 ? 272 GLN A CB 1 ATOM 2118 C CG . GLN A 1 272 ? -40.115 22.158 -24.782 1.00 19.13 ? 272 GLN A CG 1 ATOM 2119 C CD . GLN A 1 272 ? -40.969 23.369 -25.020 1.00 25.62 ? 272 GLN A CD 1 ATOM 2120 O OE1 . GLN A 1 272 ? -40.687 24.480 -24.508 1.00 27.71 ? 272 GLN A OE1 1 ATOM 2121 N NE2 . GLN A 1 272 ? -42.053 23.169 -25.769 1.00 29.13 ? 272 GLN A NE2 1 ATOM 2122 N N . VAL A 1 273 ? -37.208 21.378 -21.229 1.00 15.50 ? 273 VAL A N 1 ATOM 2123 C CA . VAL A 1 273 ? -35.997 21.489 -20.340 1.00 14.75 ? 273 VAL A CA 1 ATOM 2124 C C . VAL A 1 273 ? -34.988 20.375 -20.610 1.00 15.75 ? 273 VAL A C 1 ATOM 2125 O O . VAL A 1 273 ? -33.774 20.632 -20.761 1.00 16.84 ? 273 VAL A O 1 ATOM 2126 C CB . VAL A 1 273 ? -36.380 21.498 -18.855 1.00 15.08 ? 273 VAL A CB 1 ATOM 2127 C CG1 . VAL A 1 273 ? -35.117 21.569 -17.945 1.00 11.77 ? 273 VAL A CG1 1 ATOM 2128 C CG2 . VAL A 1 273 ? -37.238 22.683 -18.570 1.00 16.20 ? 273 VAL A CG2 1 ATOM 2129 N N . VAL A 1 274 ? -35.462 19.130 -20.637 1.00 14.86 ? 274 VAL A N 1 ATOM 2130 C CA . VAL A 1 274 ? -34.590 17.993 -20.980 1.00 15.11 ? 274 VAL A CA 1 ATOM 2131 C C . VAL A 1 274 ? -33.966 18.199 -22.353 1.00 15.14 ? 274 VAL A C 1 ATOM 2132 O O . VAL A 1 274 ? -32.733 18.046 -22.513 1.00 11.64 ? 274 VAL A O 1 ATOM 2133 C CB . VAL A 1 274 ? -35.305 16.628 -20.911 1.00 16.07 ? 274 VAL A CB 1 ATOM 2134 C CG1 . VAL A 1 274 ? -34.307 15.504 -21.228 1.00 14.43 ? 274 VAL A CG1 1 ATOM 2135 C CG2 . VAL A 1 274 ? -35.961 16.419 -19.508 1.00 13.79 ? 274 VAL A CG2 1 ATOM 2136 N N . GLN A 1 275 ? -34.784 18.589 -23.349 1.00 13.30 ? 275 GLN A N 1 ATOM 2137 C CA . GLN A 1 275 ? -34.242 18.901 -24.696 1.00 13.88 ? 275 GLN A CA 1 ATOM 2138 C C . GLN A 1 275 ? -33.151 19.984 -24.675 1.00 14.48 ? 275 GLN A C 1 ATOM 2139 O O . GLN A 1 275 ? -32.142 19.853 -25.369 1.00 13.63 ? 275 GLN A O 1 ATOM 2140 C CB . GLN A 1 275 ? -35.358 19.319 -25.675 1.00 14.55 ? 275 GLN A CB 1 ATOM 2141 C CG . GLN A 1 275 ? -36.337 18.167 -25.943 1.00 13.45 ? 275 GLN A CG 1 ATOM 2142 C CD . GLN A 1 275 ? -37.609 18.665 -26.584 1.00 19.84 ? 275 GLN A CD 1 ATOM 2143 O OE1 . GLN A 1 275 ? -37.843 19.865 -26.623 1.00 19.21 ? 275 GLN A OE1 1 ATOM 2144 N NE2 . GLN A 1 275 ? -38.441 17.740 -27.090 1.00 19.29 ? 275 GLN A NE2 1 ATOM 2145 N N . GLU A 1 276 ? -33.351 21.022 -23.854 1.00 13.56 ? 276 GLU A N 1 ATOM 2146 C CA . GLU A 1 276 ? -32.364 22.078 -23.720 1.00 14.02 ? 276 GLU A CA 1 ATOM 2147 C C . GLU A 1 276 ? -31.078 21.580 -23.065 1.00 13.61 ? 276 GLU A C 1 ATOM 2148 O O . GLU A 1 276 ? -29.995 21.932 -23.540 1.00 14.07 ? 276 GLU A O 1 ATOM 2149 C CB . GLU A 1 276 ? -32.904 23.255 -22.894 1.00 14.92 ? 276 GLU A CB 1 ATOM 2150 C CG . GLU A 1 276 ? -34.029 24.007 -23.623 1.00 16.39 ? 276 GLU A CG 1 ATOM 2151 C CD . GLU A 1 276 ? -33.518 24.738 -24.864 1.00 24.09 ? 276 GLU A CD 1 ATOM 2152 O OE1 . GLU A 1 276 ? -32.268 24.891 -25.049 1.00 25.52 ? 276 GLU A OE1 1 ATOM 2153 O OE2 . GLU A 1 276 ? -34.375 25.197 -25.637 1.00 24.92 ? 276 GLU A OE2 1 ATOM 2154 N N . TYR A 1 277 ? -31.226 20.787 -21.996 1.00 12.30 ? 277 TYR A N 1 ATOM 2155 C CA . TYR A 1 277 ? -30.080 20.190 -21.309 1.00 15.03 ? 277 TYR A CA 1 ATOM 2156 C C . TYR A 1 277 ? -29.299 19.317 -22.281 1.00 14.07 ? 277 TYR A C 1 ATOM 2157 O O . TYR A 1 277 ? -28.075 19.406 -22.382 1.00 14.09 ? 277 TYR A O 1 ATOM 2158 C CB . TYR A 1 277 ? -30.555 19.359 -20.097 1.00 15.08 ? 277 TYR A CB 1 ATOM 2159 C CG . TYR A 1 277 ? -29.431 18.575 -19.432 1.00 14.54 ? 277 TYR A CG 1 ATOM 2160 C CD1 . TYR A 1 277 ? -28.230 19.197 -19.076 1.00 15.42 ? 277 TYR A CD1 1 ATOM 2161 C CD2 . TYR A 1 277 ? -29.576 17.225 -19.167 1.00 13.87 ? 277 TYR A CD2 1 ATOM 2162 C CE1 . TYR A 1 277 ? -27.195 18.467 -18.454 1.00 16.05 ? 277 TYR A CE1 1 ATOM 2163 C CE2 . TYR A 1 277 ? -28.540 16.469 -18.578 1.00 17.18 ? 277 TYR A CE2 1 ATOM 2164 C CZ . TYR A 1 277 ? -27.365 17.104 -18.231 1.00 14.91 ? 277 TYR A CZ 1 ATOM 2165 O OH . TYR A 1 277 ? -26.351 16.364 -17.655 1.00 17.99 ? 277 TYR A OH 1 ATOM 2166 N N . LEU A 1 278 ? -30.001 18.468 -23.029 1.00 13.63 ? 278 LEU A N 1 ATOM 2167 C CA . LEU A 1 278 ? -29.278 17.546 -23.914 1.00 14.87 ? 278 LEU A CA 1 ATOM 2168 C C . LEU A 1 278 ? -28.680 18.220 -25.146 1.00 15.11 ? 278 LEU A C 1 ATOM 2169 O O . LEU A 1 278 ? -27.672 17.737 -25.726 1.00 16.12 ? 278 LEU A O 1 ATOM 2170 C CB . LEU A 1 278 ? -30.128 16.314 -24.305 1.00 15.44 ? 278 LEU A CB 1 ATOM 2171 C CG . LEU A 1 278 ? -30.704 15.561 -23.065 1.00 16.08 ? 278 LEU A CG 1 ATOM 2172 C CD1 . LEU A 1 278 ? -31.622 14.411 -23.495 1.00 13.57 ? 278 LEU A CD1 1 ATOM 2173 C CD2 . LEU A 1 278 ? -29.585 15.054 -22.114 1.00 16.71 ? 278 LEU A CD2 1 ATOM 2174 N N . GLU A 1 279 ? -29.281 19.320 -25.566 1.00 15.60 ? 279 GLU A N 1 ATOM 2175 C CA . GLU A 1 279 ? -28.698 20.115 -26.653 1.00 16.14 ? 279 GLU A CA 1 ATOM 2176 C C . GLU A 1 279 ? -27.308 20.622 -26.224 1.00 17.29 ? 279 GLU A C 1 ATOM 2177 O O . GLU A 1 279 ? -26.369 20.681 -27.025 1.00 18.39 ? 279 GLU A O 1 ATOM 2178 C CB . GLU A 1 279 ? -29.669 21.242 -27.034 1.00 16.50 ? 279 GLU A CB 1 ATOM 2179 C CG . GLU A 1 279 ? -29.077 22.396 -27.845 1.00 21.17 ? 279 GLU A CG 1 ATOM 2180 C CD . GLU A 1 279 ? -28.502 21.975 -29.193 1.00 28.74 ? 279 GLU A CD 1 ATOM 2181 O OE1 . GLU A 1 279 ? -28.968 20.973 -29.777 1.00 30.47 ? 279 GLU A OE1 1 ATOM 2182 O OE2 . GLU A 1 279 ? -27.578 22.660 -29.696 1.00 31.42 ? 279 GLU A OE2 1 ATOM 2183 N N . LEU A 1 280 ? -27.191 21.000 -24.960 1.00 17.06 ? 280 LEU A N 1 ATOM 2184 C CA . LEU A 1 280 ? -25.891 21.378 -24.397 1.00 16.87 ? 280 LEU A CA 1 ATOM 2185 C C . LEU A 1 280 ? -24.948 20.164 -24.255 1.00 16.35 ? 280 LEU A C 1 ATOM 2186 O O . LEU A 1 280 ? -23.887 20.122 -24.900 1.00 17.25 ? 280 LEU A O 1 ATOM 2187 C CB . LEU A 1 280 ? -26.059 22.126 -23.073 1.00 16.29 ? 280 LEU A CB 1 ATOM 2188 C CG . LEU A 1 280 ? -24.644 22.331 -22.484 1.00 18.81 ? 280 LEU A CG 1 ATOM 2189 C CD1 . LEU A 1 280 ? -23.874 23.362 -23.300 1.00 14.42 ? 280 LEU A CD1 1 ATOM 2190 C CD2 . LEU A 1 280 ? -24.767 22.691 -21.078 1.00 17.79 ? 280 LEU A CD2 1 ATOM 2191 N N . ILE A 1 281 ? -25.312 19.166 -23.453 1.00 16.26 ? 281 ILE A N 1 ATOM 2192 C CA . ILE A 1 281 ? -24.322 18.132 -23.055 1.00 17.02 ? 281 ILE A CA 1 ATOM 2193 C C . ILE A 1 281 ? -24.140 17.003 -24.035 1.00 16.75 ? 281 ILE A C 1 ATOM 2194 O O . ILE A 1 281 ? -23.181 16.241 -23.906 1.00 17.98 ? 281 ILE A O 1 ATOM 2195 C CB . ILE A 1 281 ? -24.646 17.387 -21.734 1.00 17.99 ? 281 ILE A CB 1 ATOM 2196 C CG1 . ILE A 1 281 ? -26.105 16.903 -21.751 1.00 17.17 ? 281 ILE A CG1 1 ATOM 2197 C CG2 . ILE A 1 281 ? -24.157 18.148 -20.501 1.00 22.67 ? 281 ILE A CG2 1 ATOM 2198 C CD1 . ILE A 1 281 ? -26.242 15.583 -21.154 1.00 19.98 ? 281 ILE A CD1 1 ATOM 2199 N N . GLY A 1 282 ? -25.047 16.865 -25.000 1.00 14.48 ? 282 GLY A N 1 ATOM 2200 C CA . GLY A 1 282 ? -24.938 15.774 -25.937 1.00 16.05 ? 282 GLY A CA 1 ATOM 2201 C C . GLY A 1 282 ? -26.143 14.854 -25.836 1.00 15.62 ? 282 GLY A C 1 ATOM 2202 O O . GLY A 1 282 ? -26.402 14.264 -24.775 1.00 15.62 ? 282 GLY A O 1 ATOM 2203 N N . ARG A 1 283 ? -26.877 14.738 -26.944 1.00 15.89 ? 283 ARG A N 1 ATOM 2204 C CA . ARG A 1 283 ? -28.032 13.829 -26.993 1.00 16.37 ? 283 ARG A CA 1 ATOM 2205 C C . ARG A 1 283 ? -27.595 12.362 -27.014 1.00 16.25 ? 283 ARG A C 1 ATOM 2206 O O . ARG A 1 283 ? -26.493 12.051 -27.486 1.00 17.98 ? 283 ARG A O 1 ATOM 2207 C CB . ARG A 1 283 ? -28.961 14.160 -28.198 1.00 15.70 ? 283 ARG A CB 1 ATOM 2208 C CG . ARG A 1 283 ? -29.856 15.359 -27.942 1.00 15.16 ? 283 ARG A CG 1 ATOM 2209 C CD . ARG A 1 283 ? -30.782 15.670 -29.172 1.00 18.10 ? 283 ARG A CD 1 ATOM 2210 N NE . ARG A 1 283 ? -30.003 16.123 -30.320 1.00 17.83 ? 283 ARG A NE 1 ATOM 2211 C CZ . ARG A 1 283 ? -29.574 17.363 -30.516 1.00 21.33 ? 283 ARG A CZ 1 ATOM 2212 N NH1 . ARG A 1 283 ? -29.851 18.339 -29.658 1.00 20.98 ? 283 ARG A NH1 1 ATOM 2213 N NH2 . ARG A 1 283 ? -28.847 17.628 -31.589 1.00 22.98 ? 283 ARG A NH2 1 ATOM 2214 N N . PRO A 1 284 ? -28.450 11.447 -26.508 1.00 16.30 ? 284 PRO A N 1 ATOM 2215 C CA . PRO A 1 284 ? -28.087 10.023 -26.446 1.00 16.23 ? 284 PRO A CA 1 ATOM 2216 C C . PRO A 1 284 ? -27.894 9.402 -27.820 1.00 15.68 ? 284 PRO A C 1 ATOM 2217 O O . PRO A 1 284 ? -28.522 9.830 -28.790 1.00 16.57 ? 284 PRO A O 1 ATOM 2218 C CB . PRO A 1 284 ? -29.307 9.369 -25.782 1.00 18.05 ? 284 PRO A CB 1 ATOM 2219 C CG . PRO A 1 284 ? -30.398 10.273 -26.021 1.00 16.95 ? 284 PRO A CG 1 ATOM 2220 C CD . PRO A 1 284 ? -29.815 11.675 -25.981 1.00 15.37 ? 284 PRO A CD 1 ATOM 2221 N N . ALA A 1 285 ? -26.964 8.456 -27.911 1.00 17.04 ? 285 ALA A N 1 ATOM 2222 C CA . ALA A 1 285 ? -26.802 7.609 -29.091 1.00 16.98 ? 285 ALA A CA 1 ATOM 2223 C C . ALA A 1 285 ? -28.129 6.933 -29.452 1.00 17.24 ? 285 ALA A C 1 ATOM 2224 O O . ALA A 1 285 ? -28.894 6.550 -28.564 1.00 16.39 ? 285 ALA A O 1 ATOM 2225 C CB . ALA A 1 285 ? -25.706 6.538 -28.837 1.00 17.04 ? 285 ALA A CB 1 ATOM 2226 N N . LEU A 1 286 ? -28.389 6.795 -30.749 1.00 17.71 ? 286 LEU A N 1 ATOM 2227 C CA . LEU A 1 286 ? -29.482 5.933 -31.209 1.00 18.44 ? 286 LEU A CA 1 ATOM 2228 C C . LEU A 1 286 ? -28.953 4.515 -31.046 1.00 17.13 ? 286 LEU A C 1 ATOM 2229 O O . LEU A 1 286 ? -27.852 4.187 -31.561 1.00 18.10 ? 286 LEU A O 1 ATOM 2230 C CB . LEU A 1 286 ? -29.820 6.245 -32.675 1.00 18.50 ? 286 LEU A CB 1 ATOM 2231 C CG . LEU A 1 286 ? -30.933 5.437 -33.317 1.00 18.64 ? 286 LEU A CG 1 ATOM 2232 C CD1 . LEU A 1 286 ? -32.303 5.841 -32.681 1.00 17.56 ? 286 LEU A CD1 1 ATOM 2233 C CD2 . LEU A 1 286 ? -30.964 5.719 -34.811 1.00 19.42 ? 286 LEU A CD2 1 ATOM 2234 N N . PRO A 1 287 ? -29.679 3.663 -30.312 1.00 17.14 ? 287 PRO A N 1 ATOM 2235 C CA . PRO A 1 287 ? -29.142 2.305 -30.099 1.00 16.44 ? 287 PRO A CA 1 ATOM 2236 C C . PRO A 1 287 ? -29.274 1.442 -31.363 1.00 15.42 ? 287 PRO A C 1 ATOM 2237 O O . PRO A 1 287 ? -30.028 1.791 -32.312 1.00 15.41 ? 287 PRO A O 1 ATOM 2238 C CB . PRO A 1 287 ? -30.056 1.726 -29.015 1.00 17.26 ? 287 PRO A CB 1 ATOM 2239 C CG . PRO A 1 287 ? -31.324 2.405 -29.244 1.00 18.39 ? 287 PRO A CG 1 ATOM 2240 C CD . PRO A 1 287 ? -31.012 3.819 -29.690 1.00 15.97 ? 287 PRO A CD 1 ATOM 2241 N N . SER A 1 288 ? -28.535 0.346 -31.390 1.00 14.92 ? 288 SER A N 1 ATOM 2242 C CA . SER A 1 288 ? -28.755 -0.699 -32.395 1.00 13.79 ? 288 SER A CA 1 ATOM 2243 C C . SER A 1 288 ? -30.124 -1.198 -32.058 1.00 14.98 ? 288 SER A C 1 ATOM 2244 O O . SER A 1 288 ? -30.481 -1.303 -30.867 1.00 13.50 ? 288 SER A O 1 ATOM 2245 C CB . SER A 1 288 ? -27.766 -1.838 -32.250 1.00 15.27 ? 288 SER A CB 1 ATOM 2246 O OG . SER A 1 288 ? -26.447 -1.398 -32.580 1.00 14.45 ? 288 SER A OG 1 ATOM 2247 N N . TYR A 1 289 ? -30.892 -1.526 -33.076 1.00 13.83 ? 289 TYR A N 1 ATOM 2248 C CA . TYR A 1 289 ? -32.271 -1.968 -32.770 1.00 14.41 ? 289 TYR A CA 1 ATOM 2249 C C . TYR A 1 289 ? -32.192 -3.267 -31.937 1.00 14.82 ? 289 TYR A C 1 ATOM 2250 O O . TYR A 1 289 ? -33.029 -3.515 -31.057 1.00 15.33 ? 289 TYR A O 1 ATOM 2251 C CB . TYR A 1 289 ? -32.956 -2.168 -34.106 1.00 14.89 ? 289 TYR A CB 1 ATOM 2252 C CG . TYR A 1 289 ? -34.436 -2.350 -34.078 1.00 15.62 ? 289 TYR A CG 1 ATOM 2253 C CD1 . TYR A 1 289 ? -35.262 -1.309 -34.417 1.00 17.60 ? 289 TYR A CD1 1 ATOM 2254 C CD2 . TYR A 1 289 ? -34.991 -3.592 -33.839 1.00 15.34 ? 289 TYR A CD2 1 ATOM 2255 C CE1 . TYR A 1 289 ? -36.673 -1.487 -34.480 1.00 17.83 ? 289 TYR A CE1 1 ATOM 2256 C CE2 . TYR A 1 289 ? -36.392 -3.781 -33.889 1.00 18.06 ? 289 TYR A CE2 1 ATOM 2257 C CZ . TYR A 1 289 ? -37.192 -2.712 -34.211 1.00 16.99 ? 289 TYR A CZ 1 ATOM 2258 O OH . TYR A 1 289 ? -38.547 -2.861 -34.294 1.00 17.46 ? 289 TYR A OH 1 ATOM 2259 N N . TRP A 1 290 ? -31.146 -4.079 -32.150 1.00 15.50 ? 290 TRP A N 1 ATOM 2260 C CA . TRP A 1 290 ? -31.040 -5.309 -31.360 1.00 16.36 ? 290 TRP A CA 1 ATOM 2261 C C . TRP A 1 290 ? -30.855 -5.124 -29.853 1.00 16.30 ? 290 TRP A C 1 ATOM 2262 O O . TRP A 1 290 ? -31.273 -5.997 -29.051 1.00 16.57 ? 290 TRP A O 1 ATOM 2263 C CB . TRP A 1 290 ? -30.023 -6.279 -31.934 1.00 17.39 ? 290 TRP A CB 1 ATOM 2264 C CG . TRP A 1 290 ? -28.623 -5.789 -31.987 1.00 16.02 ? 290 TRP A CG 1 ATOM 2265 C CD1 . TRP A 1 290 ? -27.961 -5.324 -33.064 1.00 17.12 ? 290 TRP A CD1 1 ATOM 2266 C CD2 . TRP A 1 290 ? -27.696 -5.797 -30.896 1.00 17.36 ? 290 TRP A CD2 1 ATOM 2267 N NE1 . TRP A 1 290 ? -26.634 -5.038 -32.715 1.00 15.79 ? 290 TRP A NE1 1 ATOM 2268 C CE2 . TRP A 1 290 ? -26.465 -5.314 -31.386 1.00 17.08 ? 290 TRP A CE2 1 ATOM 2269 C CE3 . TRP A 1 290 ? -27.800 -6.145 -29.539 1.00 16.25 ? 290 TRP A CE3 1 ATOM 2270 C CZ2 . TRP A 1 290 ? -25.335 -5.205 -30.576 1.00 18.81 ? 290 TRP A CZ2 1 ATOM 2271 C CZ3 . TRP A 1 290 ? -26.670 -6.040 -28.736 1.00 19.60 ? 290 TRP A CZ3 1 ATOM 2272 C CH2 . TRP A 1 290 ? -25.467 -5.575 -29.262 1.00 18.59 ? 290 TRP A CH2 1 ATOM 2273 N N . ALA A 1 291 ? -30.310 -3.973 -29.475 1.00 15.27 ? 291 ALA A N 1 ATOM 2274 C CA . ALA A 1 291 ? -30.080 -3.669 -28.054 1.00 15.56 ? 291 ALA A CA 1 ATOM 2275 C C . ALA A 1 291 ? -31.420 -3.417 -27.367 1.00 15.69 ? 291 ALA A C 1 ATOM 2276 O O . ALA A 1 291 ? -31.501 -3.444 -26.160 1.00 14.86 ? 291 ALA A O 1 ATOM 2277 C CB . ALA A 1 291 ? -29.205 -2.497 -27.930 1.00 15.65 ? 291 ALA A CB 1 ATOM 2278 N N . LEU A 1 292 ? -32.474 -3.179 -28.145 1.00 15.43 ? 292 LEU A N 1 ATOM 2279 C CA . LEU A 1 292 ? -33.816 -2.974 -27.557 1.00 15.95 ? 292 LEU A CA 1 ATOM 2280 C C . LEU A 1 292 ? -34.477 -4.259 -27.111 1.00 16.59 ? 292 LEU A C 1 ATOM 2281 O O . LEU A 1 292 ? -35.548 -4.254 -26.433 1.00 17.24 ? 292 LEU A O 1 ATOM 2282 C CB . LEU A 1 292 ? -34.746 -2.281 -28.571 1.00 16.49 ? 292 LEU A CB 1 ATOM 2283 C CG . LEU A 1 292 ? -34.422 -0.914 -29.177 1.00 18.86 ? 292 LEU A CG 1 ATOM 2284 C CD1 . LEU A 1 292 ? -35.495 -0.559 -30.219 1.00 26.03 ? 292 LEU A CD1 1 ATOM 2285 C CD2 . LEU A 1 292 ? -34.396 0.090 -28.128 1.00 23.52 ? 292 LEU A CD2 1 ATOM 2286 N N . GLY A 1 293 ? -33.923 -5.377 -27.531 1.00 16.48 ? 293 GLY A N 1 ATOM 2287 C CA . GLY A 1 293 ? -34.503 -6.643 -27.133 1.00 16.32 ? 293 GLY A CA 1 ATOM 2288 C C . GLY A 1 293 ? -34.107 -7.026 -25.726 1.00 16.32 ? 293 GLY A C 1 ATOM 2289 O O . GLY A 1 293 ? -33.463 -6.240 -24.971 1.00 17.16 ? 293 GLY A O 1 ATOM 2290 N N . PHE A 1 294 ? -34.454 -8.247 -25.360 1.00 15.34 ? 294 PHE A N 1 ATOM 2291 C CA . PHE A 1 294 ? -34.198 -8.742 -24.016 1.00 14.93 ? 294 PHE A CA 1 ATOM 2292 C C . PHE A 1 294 ? -32.780 -9.284 -23.938 1.00 14.82 ? 294 PHE A C 1 ATOM 2293 O O . PHE A 1 294 ? -32.351 -10.002 -24.843 1.00 16.31 ? 294 PHE A O 1 ATOM 2294 C CB . PHE A 1 294 ? -35.178 -9.849 -23.703 1.00 13.63 ? 294 PHE A CB 1 ATOM 2295 C CG . PHE A 1 294 ? -35.012 -10.449 -22.332 1.00 14.82 ? 294 PHE A CG 1 ATOM 2296 C CD1 . PHE A 1 294 ? -35.210 -9.664 -21.182 1.00 11.62 ? 294 PHE A CD1 1 ATOM 2297 C CD2 . PHE A 1 294 ? -34.625 -11.782 -22.195 1.00 15.12 ? 294 PHE A CD2 1 ATOM 2298 C CE1 . PHE A 1 294 ? -35.058 -10.209 -19.898 1.00 15.21 ? 294 PHE A CE1 1 ATOM 2299 C CE2 . PHE A 1 294 ? -34.471 -12.360 -20.908 1.00 14.99 ? 294 PHE A CE2 1 ATOM 2300 C CZ . PHE A 1 294 ? -34.685 -11.555 -19.757 1.00 16.58 ? 294 PHE A CZ 1 ATOM 2301 N N . HIS A 1 295 ? -32.060 -8.914 -22.882 1.00 14.97 ? 295 HIS A N 1 ATOM 2302 C CA . HIS A 1 295 ? -30.684 -9.369 -22.642 1.00 14.92 ? 295 HIS A CA 1 ATOM 2303 C C . HIS A 1 295 ? -30.675 -10.356 -21.458 1.00 14.57 ? 295 HIS A C 1 ATOM 2304 O O . HIS A 1 295 ? -31.338 -10.137 -20.432 1.00 14.51 ? 295 HIS A O 1 ATOM 2305 C CB . HIS A 1 295 ? -29.745 -8.201 -22.247 1.00 14.24 ? 295 HIS A CB 1 ATOM 2306 C CG . HIS A 1 295 ? -29.636 -7.089 -23.254 1.00 14.19 ? 295 HIS A CG 1 ATOM 2307 N ND1 . HIS A 1 295 ? -30.731 -6.363 -23.717 1.00 18.10 ? 295 HIS A ND1 1 ATOM 2308 C CD2 . HIS A 1 295 ? -28.551 -6.536 -23.835 1.00 10.52 ? 295 HIS A CD2 1 ATOM 2309 C CE1 . HIS A 1 295 ? -30.309 -5.429 -24.557 1.00 11.94 ? 295 HIS A CE1 1 ATOM 2310 N NE2 . HIS A 1 295 ? -28.992 -5.532 -24.658 1.00 17.02 ? 295 HIS A NE2 1 ATOM 2311 N N . LEU A 1 296 ? -29.837 -11.391 -21.535 1.00 16.54 ? 296 LEU A N 1 ATOM 2312 C CA . LEU A 1 296 ? -29.682 -12.328 -20.408 1.00 16.45 ? 296 LEU A CA 1 ATOM 2313 C C . LEU A 1 296 ? -28.213 -12.421 -20.001 1.00 17.40 ? 296 LEU A C 1 ATOM 2314 O O . LEU A 1 296 ? -27.299 -12.347 -20.852 1.00 17.03 ? 296 LEU A O 1 ATOM 2315 C CB . LEU A 1 296 ? -30.200 -13.706 -20.798 1.00 17.18 ? 296 LEU A CB 1 ATOM 2316 C CG . LEU A 1 296 ? -30.439 -14.771 -19.714 1.00 18.51 ? 296 LEU A CG 1 ATOM 2317 C CD1 . LEU A 1 296 ? -31.449 -14.315 -18.614 1.00 16.76 ? 296 LEU A CD1 1 ATOM 2318 C CD2 . LEU A 1 296 ? -30.917 -16.058 -20.389 1.00 17.13 ? 296 LEU A CD2 1 ATOM 2319 N N . SER A 1 297 ? -28.004 -12.601 -18.710 1.00 18.44 ? 297 SER A N 1 ATOM 2320 C CA . SER A 1 297 ? -26.665 -12.535 -18.147 1.00 19.82 ? 297 SER A CA 1 ATOM 2321 C C . SER A 1 297 ? -26.616 -13.232 -16.792 1.00 19.91 ? 297 SER A C 1 ATOM 2322 O O . SER A 1 297 ? -27.631 -13.389 -16.112 1.00 19.70 ? 297 SER A O 1 ATOM 2323 C CB . SER A 1 297 ? -26.293 -11.052 -17.966 1.00 19.75 ? 297 SER A CB 1 ATOM 2324 O OG . SER A 1 297 ? -24.927 -10.897 -17.603 1.00 22.07 ? 297 SER A OG 1 ATOM 2325 N N . ARG A 1 298 ? -25.424 -13.653 -16.377 1.00 18.41 ? 298 ARG A N 1 ATOM 2326 C CA . ARG A 1 298 ? -25.183 -13.840 -14.951 1.00 18.98 ? 298 ARG A CA 1 ATOM 2327 C C . ARG A 1 298 ? -23.703 -13.807 -14.735 1.00 19.08 ? 298 ARG A C 1 ATOM 2328 O O . ARG A 1 298 ? -22.930 -14.040 -15.663 1.00 17.51 ? 298 ARG A O 1 ATOM 2329 C CB . ARG A 1 298 ? -25.786 -15.123 -14.336 1.00 18.84 ? 298 ARG A CB 1 ATOM 2330 C CG . ARG A 1 298 ? -24.978 -16.407 -14.538 1.00 22.67 ? 298 ARG A CG 1 ATOM 2331 C CD . ARG A 1 298 ? -25.447 -17.556 -13.624 1.00 22.48 ? 298 ARG A CD 1 ATOM 2332 N NE . ARG A 1 298 ? -25.229 -17.294 -12.190 1.00 25.87 ? 298 ARG A NE 1 ATOM 2333 C CZ . ARG A 1 298 ? -25.966 -17.832 -11.215 1.00 23.33 ? 298 ARG A CZ 1 ATOM 2334 N NH1 . ARG A 1 298 ? -26.955 -18.659 -11.505 1.00 23.43 ? 298 ARG A NH1 1 ATOM 2335 N NH2 . ARG A 1 298 ? -25.726 -17.538 -9.944 1.00 22.31 ? 298 ARG A NH2 1 ATOM 2336 N N . TYR A 1 299 ? -23.341 -13.499 -13.500 1.00 19.30 ? 299 TYR A N 1 ATOM 2337 C CA . TYR A 1 299 ? -21.985 -13.611 -13.016 1.00 20.02 ? 299 TYR A CA 1 ATOM 2338 C C . TYR A 1 299 ? -21.803 -15.094 -12.659 1.00 20.98 ? 299 TYR A C 1 ATOM 2339 O O . TYR A 1 299 ? -22.584 -15.678 -11.889 1.00 20.56 ? 299 TYR A O 1 ATOM 2340 C CB . TYR A 1 299 ? -21.835 -12.714 -11.793 1.00 20.20 ? 299 TYR A CB 1 ATOM 2341 C CG . TYR A 1 299 ? -20.451 -12.682 -11.150 1.00 20.25 ? 299 TYR A CG 1 ATOM 2342 C CD1 . TYR A 1 299 ? -20.301 -12.259 -9.827 1.00 22.78 ? 299 TYR A CD1 1 ATOM 2343 C CD2 . TYR A 1 299 ? -19.333 -13.056 -11.844 1.00 18.88 ? 299 TYR A CD2 1 ATOM 2344 C CE1 . TYR A 1 299 ? -19.046 -12.206 -9.214 1.00 23.17 ? 299 TYR A CE1 1 ATOM 2345 C CE2 . TYR A 1 299 ? -18.053 -13.010 -11.234 1.00 22.79 ? 299 TYR A CE2 1 ATOM 2346 C CZ . TYR A 1 299 ? -17.935 -12.582 -9.918 1.00 22.13 ? 299 TYR A CZ 1 ATOM 2347 O OH . TYR A 1 299 ? -16.695 -12.538 -9.300 1.00 23.58 ? 299 TYR A OH 1 ATOM 2348 N N . GLU A 1 300 ? -20.805 -15.713 -13.285 1.00 21.99 ? 300 GLU A N 1 ATOM 2349 C CA . GLU A 1 300 ? -20.433 -17.097 -13.005 1.00 23.56 ? 300 GLU A CA 1 ATOM 2350 C C . GLU A 1 300 ? -21.470 -18.120 -13.444 1.00 23.64 ? 300 GLU A C 1 ATOM 2351 O O . GLU A 1 300 ? -22.073 -18.813 -12.619 1.00 24.69 ? 300 GLU A O 1 ATOM 2352 C CB . GLU A 1 300 ? -20.028 -17.307 -11.531 1.00 24.26 ? 300 GLU A CB 1 ATOM 2353 C CG . GLU A 1 300 ? -18.665 -16.687 -11.151 1.00 27.52 ? 300 GLU A CG 1 ATOM 2354 C CD . GLU A 1 300 ? -17.440 -17.413 -11.703 1.00 33.25 ? 300 GLU A CD 1 ATOM 2355 O OE1 . GLU A 1 300 ? -17.540 -18.601 -12.112 1.00 34.94 ? 300 GLU A OE1 1 ATOM 2356 O OE2 . GLU A 1 300 ? -16.356 -16.779 -11.704 1.00 36.49 ? 300 GLU A OE2 1 ATOM 2357 N N . TYR A 1 301 ? -21.677 -18.208 -14.751 1.00 22.73 ? 301 TYR A N 1 ATOM 2358 C CA . TYR A 1 301 ? -22.081 -19.491 -15.332 1.00 22.01 ? 301 TYR A CA 1 ATOM 2359 C C . TYR A 1 301 ? -21.037 -20.555 -14.973 1.00 22.54 ? 301 TYR A C 1 ATOM 2360 O O . TYR A 1 301 ? -21.383 -21.692 -14.694 1.00 22.02 ? 301 TYR A O 1 ATOM 2361 C CB . TYR A 1 301 ? -22.220 -19.400 -16.839 1.00 21.20 ? 301 TYR A CB 1 ATOM 2362 C CG . TYR A 1 301 ? -23.387 -18.540 -17.249 1.00 19.99 ? 301 TYR A CG 1 ATOM 2363 C CD1 . TYR A 1 301 ? -24.701 -19.001 -17.085 1.00 20.89 ? 301 TYR A CD1 1 ATOM 2364 C CD2 . TYR A 1 301 ? -23.183 -17.264 -17.789 1.00 20.02 ? 301 TYR A CD2 1 ATOM 2365 C CE1 . TYR A 1 301 ? -25.793 -18.210 -17.466 1.00 19.25 ? 301 TYR A CE1 1 ATOM 2366 C CE2 . TYR A 1 301 ? -24.272 -16.453 -18.196 1.00 20.97 ? 301 TYR A CE2 1 ATOM 2367 C CZ . TYR A 1 301 ? -25.573 -16.938 -18.021 1.00 20.49 ? 301 TYR A CZ 1 ATOM 2368 O OH . TYR A 1 301 ? -26.708 -16.182 -18.376 1.00 20.34 ? 301 TYR A OH 1 ATOM 2369 N N . GLY A 1 302 ? -19.766 -20.161 -14.998 1.00 22.50 ? 302 GLY A N 1 ATOM 2370 C CA . GLY A 1 302 ? -18.657 -21.028 -14.563 1.00 23.83 ? 302 GLY A CA 1 ATOM 2371 C C . GLY A 1 302 ? -17.996 -21.706 -15.749 1.00 23.51 ? 302 GLY A C 1 ATOM 2372 O O . GLY A 1 302 ? -16.751 -21.688 -15.894 1.00 24.07 ? 302 GLY A O 1 ATOM 2373 N N . THR A 1 303 ? -18.838 -22.287 -16.603 1.00 23.16 ? 303 THR A N 1 ATOM 2374 C CA . THR A 1 303 ? -18.409 -22.952 -17.832 1.00 23.62 ? 303 THR A CA 1 ATOM 2375 C C . THR A 1 303 ? -19.304 -22.582 -19.017 1.00 23.83 ? 303 THR A C 1 ATOM 2376 O O . THR A 1 303 ? -20.490 -22.236 -18.846 1.00 22.60 ? 303 THR A O 1 ATOM 2377 C CB . THR A 1 303 ? -18.429 -24.506 -17.727 1.00 23.11 ? 303 THR A CB 1 ATOM 2378 O OG1 . THR A 1 303 ? -19.785 -24.977 -17.633 1.00 24.72 ? 303 THR A OG1 1 ATOM 2379 C CG2 . THR A 1 303 ? -17.635 -24.999 -16.509 1.00 24.26 ? 303 THR A CG2 1 ATOM 2380 N N . LEU A 1 304 ? -18.730 -22.714 -20.214 1.00 23.76 ? 304 LEU A N 1 ATOM 2381 C CA . LEU A 1 304 ? -19.483 -22.511 -21.442 1.00 24.01 ? 304 LEU A CA 1 ATOM 2382 C C . LEU A 1 304 ? -20.639 -23.507 -21.524 1.00 24.68 ? 304 LEU A C 1 ATOM 2383 O O . LEU A 1 304 ? -21.729 -23.163 -21.996 1.00 24.27 ? 304 LEU A O 1 ATOM 2384 C CB . LEU A 1 304 ? -18.569 -22.621 -22.650 1.00 23.51 ? 304 LEU A CB 1 ATOM 2385 C CG . LEU A 1 304 ? -19.173 -22.324 -24.029 1.00 24.73 ? 304 LEU A CG 1 ATOM 2386 C CD1 . LEU A 1 304 ? -19.909 -20.992 -24.036 1.00 22.76 ? 304 LEU A CD1 1 ATOM 2387 C CD2 . LEU A 1 304 ? -18.074 -22.311 -25.108 1.00 22.30 ? 304 LEU A CD2 1 ATOM 2388 N N . ASP A 1 305 ? -20.422 -24.734 -21.042 1.00 24.99 ? 305 ASP A N 1 ATOM 2389 C CA . ASP A 1 305 ? -21.503 -25.729 -20.974 1.00 25.84 ? 305 ASP A CA 1 ATOM 2390 C C . ASP A 1 305 ? -22.688 -25.229 -20.169 1.00 25.08 ? 305 ASP A C 1 ATOM 2391 O O . ASP A 1 305 ? -23.848 -25.426 -20.573 1.00 23.65 ? 305 ASP A O 1 ATOM 2392 C CB . ASP A 1 305 ? -21.031 -27.064 -20.370 1.00 27.31 ? 305 ASP A CB 1 ATOM 2393 C CG . ASP A 1 305 ? -20.184 -27.907 -21.342 1.00 32.39 ? 305 ASP A CG 1 ATOM 2394 O OD1 . ASP A 1 305 ? -20.047 -27.547 -22.534 1.00 36.73 ? 305 ASP A OD1 1 ATOM 2395 O OD2 . ASP A 1 305 ? -19.652 -28.957 -20.891 1.00 38.31 ? 305 ASP A OD2 1 ATOM 2396 N N . ASN A 1 306 ? -22.412 -24.609 -19.023 1.00 24.63 ? 306 ASN A N 1 ATOM 2397 C CA . ASN A 1 306 ? -23.495 -24.056 -18.168 1.00 25.67 ? 306 ASN A CA 1 ATOM 2398 C C . ASN A 1 306 ? -24.196 -22.893 -18.856 1.00 24.46 ? 306 ASN A C 1 ATOM 2399 O O . ASN A 1 306 ? -25.425 -22.789 -18.802 1.00 25.98 ? 306 ASN A O 1 ATOM 2400 C CB . ASN A 1 306 ? -22.959 -23.612 -16.798 1.00 25.79 ? 306 ASN A CB 1 ATOM 2401 C CG . ASN A 1 306 ? -22.567 -24.803 -15.911 1.00 28.49 ? 306 ASN A CG 1 ATOM 2402 O OD1 . ASN A 1 306 ? -22.972 -25.932 -16.170 1.00 30.50 ? 306 ASN A OD1 1 ATOM 2403 N ND2 . ASN A 1 306 ? -21.753 -24.552 -14.889 1.00 27.38 ? 306 ASN A ND2 1 ATOM 2404 N N . MET A 1 307 ? -23.414 -22.025 -19.484 1.00 23.61 ? 307 MET A N 1 ATOM 2405 C CA . MET A 1 307 ? -23.964 -20.881 -20.233 1.00 23.95 ? 307 MET A CA 1 ATOM 2406 C C . MET A 1 307 ? -24.810 -21.392 -21.387 1.00 24.12 ? 307 MET A C 1 ATOM 2407 O O . MET A 1 307 ? -25.949 -20.968 -21.544 1.00 23.02 ? 307 MET A O 1 ATOM 2408 C CB . MET A 1 307 ? -22.873 -19.933 -20.733 1.00 23.21 ? 307 MET A CB 1 ATOM 2409 C CG . MET A 1 307 ? -23.405 -18.717 -21.529 1.00 22.65 ? 307 MET A CG 1 ATOM 2410 S SD . MET A 1 307 ? -22.052 -17.787 -22.211 1.00 27.50 ? 307 MET A SD 1 ATOM 2411 C CE . MET A 1 307 ? -21.397 -16.976 -20.760 1.00 25.04 ? 307 MET A CE 1 ATOM 2412 N N . ARG A 1 308 ? -24.274 -22.354 -22.155 1.00 23.83 ? 308 ARG A N 1 ATOM 2413 C CA . ARG A 1 308 ? -25.013 -22.922 -23.274 1.00 25.82 ? 308 ARG A CA 1 ATOM 2414 C C . ARG A 1 308 ? -26.319 -23.593 -22.832 1.00 24.53 ? 308 ARG A C 1 ATOM 2415 O O . ARG A 1 308 ? -27.315 -23.479 -23.531 1.00 24.22 ? 308 ARG A O 1 ATOM 2416 C CB . ARG A 1 308 ? -24.096 -23.832 -24.111 1.00 25.68 ? 308 ARG A CB 1 ATOM 2417 C CG . ARG A 1 308 ? -24.758 -24.702 -25.171 1.00 31.66 ? 308 ARG A CG 1 ATOM 2418 C CD . ARG A 1 308 ? -23.671 -25.597 -25.817 1.00 31.00 ? 308 ARG A CD 1 ATOM 2419 N NE . ARG A 1 308 ? -22.828 -24.882 -26.770 1.00 39.46 ? 308 ARG A NE 1 ATOM 2420 C CZ . ARG A 1 308 ? -21.501 -24.986 -26.818 1.00 41.96 ? 308 ARG A CZ 1 ATOM 2421 N NH1 . ARG A 1 308 ? -20.861 -25.742 -25.937 1.00 44.73 ? 308 ARG A NH1 1 ATOM 2422 N NH2 . ARG A 1 308 ? -20.808 -24.327 -27.734 1.00 43.18 ? 308 ARG A NH2 1 ATOM 2423 N N . GLU A 1 309 ? -26.332 -24.262 -21.680 1.00 24.00 ? 309 GLU A N 1 ATOM 2424 C CA . GLU A 1 309 ? -27.561 -24.888 -21.160 1.00 26.25 ? 309 GLU A CA 1 ATOM 2425 C C . GLU A 1 309 ? -28.659 -23.846 -20.828 1.00 24.14 ? 309 GLU A C 1 ATOM 2426 O O . GLU A 1 309 ? -29.865 -24.047 -21.089 1.00 23.72 ? 309 GLU A O 1 ATOM 2427 C CB . GLU A 1 309 ? -27.250 -25.752 -19.918 1.00 26.09 ? 309 GLU A CB 1 ATOM 2428 C CG . GLU A 1 309 ? -28.512 -26.320 -19.223 1.00 30.81 ? 309 GLU A CG 1 ATOM 2429 C CD . GLU A 1 309 ? -28.208 -27.144 -17.953 1.00 32.37 ? 309 GLU A CD 1 ATOM 2430 O OE1 . GLU A 1 309 ? -27.003 -27.279 -17.582 1.00 36.41 ? 309 GLU A OE1 1 ATOM 2431 O OE2 . GLU A 1 309 ? -29.199 -27.608 -17.307 1.00 37.72 ? 309 GLU A OE2 1 ATOM 2432 N N . VAL A 1 310 ? -28.237 -22.733 -20.240 1.00 22.94 ? 310 VAL A N 1 ATOM 2433 C CA . VAL A 1 310 ? -29.137 -21.611 -19.963 1.00 21.58 ? 310 VAL A CA 1 ATOM 2434 C C . VAL A 1 310 ? -29.696 -21.011 -21.255 1.00 20.78 ? 310 VAL A C 1 ATOM 2435 O O . VAL A 1 310 ? -30.919 -20.809 -21.369 1.00 20.45 ? 310 VAL A O 1 ATOM 2436 C CB . VAL A 1 310 ? -28.412 -20.523 -19.083 1.00 21.65 ? 310 VAL A CB 1 ATOM 2437 C CG1 . VAL A 1 310 ? -29.268 -19.267 -18.933 1.00 20.10 ? 310 VAL A CG1 1 ATOM 2438 C CG2 . VAL A 1 310 ? -28.107 -21.121 -17.713 1.00 22.57 ? 310 VAL A CG2 1 ATOM 2439 N N . VAL A 1 311 ? -28.809 -20.741 -22.216 1.00 20.21 ? 311 VAL A N 1 ATOM 2440 C CA . VAL A 1 311 ? -29.186 -20.204 -23.521 1.00 20.68 ? 311 VAL A CA 1 ATOM 2441 C C . VAL A 1 311 ? -30.230 -21.139 -24.139 1.00 21.41 ? 311 VAL A C 1 ATOM 2442 O O . VAL A 1 311 ? -31.300 -20.698 -24.588 1.00 20.96 ? 311 VAL A O 1 ATOM 2443 C CB . VAL A 1 311 ? -27.965 -20.069 -24.488 1.00 20.62 ? 311 VAL A CB 1 ATOM 2444 C CG1 . VAL A 1 311 ? -28.417 -19.678 -25.896 1.00 21.23 ? 311 VAL A CG1 1 ATOM 2445 C CG2 . VAL A 1 311 ? -26.962 -19.009 -23.993 1.00 19.95 ? 311 VAL A CG2 1 ATOM 2446 N N . GLU A 1 312 ? -29.936 -22.435 -24.115 1.00 21.91 ? 312 GLU A N 1 ATOM 2447 C CA . GLU A 1 312 ? -30.752 -23.382 -24.819 1.00 23.31 ? 312 GLU A CA 1 ATOM 2448 C C . GLU A 1 312 ? -32.132 -23.581 -24.195 1.00 22.99 ? 312 GLU A C 1 ATOM 2449 O O . GLU A 1 312 ? -33.098 -23.685 -24.949 1.00 23.01 ? 312 GLU A O 1 ATOM 2450 C CB . GLU A 1 312 ? -29.985 -24.675 -25.113 1.00 25.29 ? 312 GLU A CB 1 ATOM 2451 C CG . GLU A 1 312 ? -28.970 -24.454 -26.273 1.00 32.09 ? 312 GLU A CG 1 ATOM 2452 C CD . GLU A 1 312 ? -29.608 -23.766 -27.534 1.00 41.59 ? 312 GLU A CD 1 ATOM 2453 O OE1 . GLU A 1 312 ? -30.652 -24.281 -28.047 1.00 46.85 ? 312 GLU A OE1 1 ATOM 2454 O OE2 . GLU A 1 312 ? -29.060 -22.725 -28.019 1.00 42.36 ? 312 GLU A OE2 1 ATOM 2455 N N . ARG A 1 313 ? -32.256 -23.566 -22.861 1.00 21.51 ? 313 ARG A N 1 ATOM 2456 C CA . ARG A 1 313 ? -33.613 -23.706 -22.257 1.00 22.16 ? 313 ARG A CA 1 ATOM 2457 C C . ARG A 1 313 ? -34.496 -22.468 -22.468 1.00 21.39 ? 313 ARG A C 1 ATOM 2458 O O . ARG A 1 313 ? -35.739 -22.580 -22.598 1.00 21.65 ? 313 ARG A O 1 ATOM 2459 C CB . ARG A 1 313 ? -33.590 -24.145 -20.788 1.00 21.93 ? 313 ARG A CB 1 ATOM 2460 C CG . ARG A 1 313 ? -32.920 -23.156 -19.837 1.00 22.73 ? 313 ARG A CG 1 ATOM 2461 C CD . ARG A 1 313 ? -33.228 -23.545 -18.412 1.00 24.30 ? 313 ARG A CD 1 ATOM 2462 N NE . ARG A 1 313 ? -32.540 -22.671 -17.480 1.00 24.10 ? 313 ARG A NE 1 ATOM 2463 C CZ . ARG A 1 313 ? -31.619 -23.076 -16.610 1.00 26.96 ? 313 ARG A CZ 1 ATOM 2464 N NH1 . ARG A 1 313 ? -31.284 -24.365 -16.521 1.00 29.73 ? 313 ARG A NH1 1 ATOM 2465 N NH2 . ARG A 1 313 ? -31.052 -22.198 -15.795 1.00 25.64 ? 313 ARG A NH2 1 ATOM 2466 N N . ASN A 1 314 ? -33.864 -21.298 -22.531 1.00 20.80 ? 314 ASN A N 1 ATOM 2467 C CA . ASN A 1 314 ? -34.595 -20.063 -22.859 1.00 21.36 ? 314 ASN A CA 1 ATOM 2468 C C . ASN A 1 314 ? -34.996 -19.967 -24.318 1.00 21.90 ? 314 ASN A C 1 ATOM 2469 O O . ASN A 1 314 ? -36.116 -19.533 -24.624 1.00 21.58 ? 314 ASN A O 1 ATOM 2470 C CB . ASN A 1 314 ? -33.853 -18.826 -22.343 1.00 21.45 ? 314 ASN A CB 1 ATOM 2471 C CG . ASN A 1 314 ? -33.917 -18.733 -20.834 1.00 20.95 ? 314 ASN A CG 1 ATOM 2472 O OD1 . ASN A 1 314 ? -34.912 -18.260 -20.271 1.00 18.82 ? 314 ASN A OD1 1 ATOM 2473 N ND2 . ASN A 1 314 ? -32.893 -19.242 -20.164 1.00 17.43 ? 314 ASN A ND2 1 ATOM 2474 N N . ARG A 1 315 ? -34.115 -20.413 -25.218 1.00 21.32 ? 315 ARG A N 1 ATOM 2475 C CA . ARG A 1 315 ? -34.493 -20.577 -26.623 1.00 21.70 ? 315 ARG A CA 1 ATOM 2476 C C . ARG A 1 315 ? -35.599 -21.618 -26.848 1.00 22.36 ? 315 ARG A C 1 ATOM 2477 O O . ARG A 1 315 ? -36.561 -21.361 -27.596 1.00 22.62 ? 315 ARG A O 1 ATOM 2478 C CB . ARG A 1 315 ? -33.267 -20.895 -27.468 1.00 21.40 ? 315 ARG A CB 1 ATOM 2479 C CG . ARG A 1 315 ? -32.379 -19.685 -27.650 1.00 21.21 ? 315 ARG A CG 1 ATOM 2480 C CD . ARG A 1 315 ? -31.325 -19.924 -28.687 1.00 24.81 ? 315 ARG A CD 1 ATOM 2481 N NE . ARG A 1 315 ? -31.911 -19.963 -30.008 1.00 29.44 ? 315 ARG A NE 1 ATOM 2482 C CZ . ARG A 1 315 ? -32.098 -21.068 -30.727 1.00 34.48 ? 315 ARG A CZ 1 ATOM 2483 N NH1 . ARG A 1 315 ? -31.724 -22.264 -30.262 1.00 36.82 ? 315 ARG A NH1 1 ATOM 2484 N NH2 . ARG A 1 315 ? -32.642 -20.969 -31.933 1.00 35.77 ? 315 ARG A NH2 1 ATOM 2485 N N . ALA A 1 316 ? -35.491 -22.768 -26.170 1.00 22.78 ? 316 ALA A N 1 ATOM 2486 C CA . ALA A 1 316 ? -36.515 -23.833 -26.253 1.00 23.50 ? 316 ALA A CA 1 ATOM 2487 C C . ALA A 1 316 ? -37.897 -23.332 -25.810 1.00 23.82 ? 316 ALA A C 1 ATOM 2488 O O . ALA A 1 316 ? -38.945 -23.740 -26.363 1.00 23.65 ? 316 ALA A O 1 ATOM 2489 C CB . ALA A 1 316 ? -36.100 -25.040 -25.400 1.00 23.87 ? 316 ALA A CB 1 ATOM 2490 N N . ALA A 1 317 ? -37.896 -22.425 -24.837 1.00 23.00 ? 317 ALA A N 1 ATOM 2491 C CA . ALA A 1 317 ? -39.126 -21.793 -24.345 1.00 22.78 ? 317 ALA A CA 1 ATOM 2492 C C . ALA A 1 317 ? -39.697 -20.696 -25.270 1.00 22.23 ? 317 ALA A C 1 ATOM 2493 O O . ALA A 1 317 ? -40.788 -20.175 -24.989 1.00 23.20 ? 317 ALA A O 1 ATOM 2494 C CB . ALA A 1 317 ? -38.899 -21.241 -22.943 1.00 22.70 ? 317 ALA A CB 1 ATOM 2495 N N . GLN A 1 318 ? -39.002 -20.368 -26.358 1.00 21.00 ? 318 GLN A N 1 ATOM 2496 C CA . GLN A 1 318 ? -39.429 -19.320 -27.316 1.00 22.81 ? 318 GLN A CA 1 ATOM 2497 C C . GLN A 1 318 ? -39.490 -17.957 -26.621 1.00 22.91 ? 318 GLN A C 1 ATOM 2498 O O . GLN A 1 318 ? -40.400 -17.158 -26.867 1.00 23.76 ? 318 GLN A O 1 ATOM 2499 C CB . GLN A 1 318 ? -40.805 -19.617 -27.997 1.00 23.54 ? 318 GLN A CB 1 ATOM 2500 C CG . GLN A 1 318 ? -40.893 -20.973 -28.757 1.00 25.96 ? 318 GLN A CG 1 ATOM 2501 C CD . GLN A 1 318 ? -39.695 -21.191 -29.675 1.00 29.90 ? 318 GLN A CD 1 ATOM 2502 O OE1 . GLN A 1 318 ? -39.418 -20.389 -30.574 1.00 31.64 ? 318 GLN A OE1 1 ATOM 2503 N NE2 . GLN A 1 318 ? -38.952 -22.266 -29.427 1.00 33.78 ? 318 GLN A NE2 1 ATOM 2504 N N . LEU A 1 319 ? -38.542 -17.717 -25.724 1.00 22.69 ? 319 LEU A N 1 ATOM 2505 C CA . LEU A 1 319 ? -38.477 -16.428 -25.028 1.00 22.91 ? 319 LEU A CA 1 ATOM 2506 C C . LEU A 1 319 ? -37.954 -15.418 -26.038 1.00 21.79 ? 319 LEU A C 1 ATOM 2507 O O . LEU A 1 319 ? -36.957 -15.687 -26.737 1.00 22.33 ? 319 LEU A O 1 ATOM 2508 C CB . LEU A 1 319 ? -37.535 -16.517 -23.816 1.00 21.74 ? 319 LEU A CB 1 ATOM 2509 C CG . LEU A 1 319 ? -37.626 -15.345 -22.825 1.00 21.84 ? 319 LEU A CG 1 ATOM 2510 C CD1 . LEU A 1 319 ? -38.915 -15.391 -21.956 1.00 21.06 ? 319 LEU A CD1 1 ATOM 2511 C CD2 . LEU A 1 319 ? -36.369 -15.296 -21.982 1.00 19.29 ? 319 LEU A CD2 1 ATOM 2512 N N . PRO A 1 320 ? -38.594 -14.242 -26.121 1.00 21.13 ? 320 PRO A N 1 ATOM 2513 C CA . PRO A 1 320 ? -37.949 -13.206 -26.918 1.00 20.03 ? 320 PRO A CA 1 ATOM 2514 C C . PRO A 1 320 ? -36.614 -12.883 -26.211 1.00 19.51 ? 320 PRO A C 1 ATOM 2515 O O . PRO A 1 320 ? -36.596 -12.692 -24.986 1.00 19.37 ? 320 PRO A O 1 ATOM 2516 C CB . PRO A 1 320 ? -38.948 -12.058 -26.845 1.00 19.75 ? 320 PRO A CB 1 ATOM 2517 C CG . PRO A 1 320 ? -40.236 -12.741 -26.490 1.00 20.37 ? 320 PRO A CG 1 ATOM 2518 C CD . PRO A 1 320 ? -39.851 -13.763 -25.527 1.00 20.04 ? 320 PRO A CD 1 ATOM 2519 N N . TYR A 1 321 ? -35.502 -12.888 -26.954 1.00 19.16 ? 321 TYR A N 1 ATOM 2520 C CA . TYR A 1 321 ? -34.189 -13.037 -26.325 1.00 18.61 ? 321 TYR A CA 1 ATOM 2521 C C . TYR A 1 321 ? -33.105 -12.744 -27.335 1.00 18.63 ? 321 TYR A C 1 ATOM 2522 O O . TYR A 1 321 ? -32.758 -13.603 -28.160 1.00 19.10 ? 321 TYR A O 1 ATOM 2523 C CB . TYR A 1 321 ? -34.087 -14.467 -25.721 1.00 18.69 ? 321 TYR A CB 1 ATOM 2524 C CG . TYR A 1 321 ? -32.746 -15.026 -25.206 1.00 19.22 ? 321 TYR A CG 1 ATOM 2525 C CD1 . TYR A 1 321 ? -31.687 -14.213 -24.798 1.00 17.94 ? 321 TYR A CD1 1 ATOM 2526 C CD2 . TYR A 1 321 ? -32.597 -16.404 -25.062 1.00 19.86 ? 321 TYR A CD2 1 ATOM 2527 C CE1 . TYR A 1 321 ? -30.469 -14.802 -24.286 1.00 16.69 ? 321 TYR A CE1 1 ATOM 2528 C CE2 . TYR A 1 321 ? -31.428 -16.977 -24.558 1.00 21.87 ? 321 TYR A CE2 1 ATOM 2529 C CZ . TYR A 1 321 ? -30.378 -16.171 -24.181 1.00 19.71 ? 321 TYR A CZ 1 ATOM 2530 O OH . TYR A 1 321 ? -29.255 -16.769 -23.704 1.00 23.37 ? 321 TYR A OH 1 ATOM 2531 N N . ASP A 1 322 ? -32.599 -11.511 -27.313 1.00 17.18 ? 322 ASP A N 1 ATOM 2532 C CA . ASP A 1 322 ? -31.736 -11.068 -28.377 1.00 17.45 ? 322 ASP A CA 1 ATOM 2533 C C . ASP A 1 322 ? -30.265 -11.147 -28.013 1.00 17.20 ? 322 ASP A C 1 ATOM 2534 O O . ASP A 1 322 ? -29.394 -11.314 -28.910 1.00 17.38 ? 322 ASP A O 1 ATOM 2535 C CB . ASP A 1 322 ? -32.053 -9.633 -28.758 1.00 18.16 ? 322 ASP A CB 1 ATOM 2536 C CG . ASP A 1 322 ? -32.990 -9.552 -29.923 1.00 20.69 ? 322 ASP A CG 1 ATOM 2537 O OD1 . ASP A 1 322 ? -32.496 -9.239 -31.033 1.00 21.89 ? 322 ASP A OD1 1 ATOM 2538 O OD2 . ASP A 1 322 ? -34.203 -9.829 -29.699 1.00 21.17 ? 322 ASP A OD2 1 ATOM 2539 N N . VAL A 1 323 ? -29.982 -10.987 -26.721 1.00 16.68 ? 323 VAL A N 1 ATOM 2540 C CA . VAL A 1 323 ? -28.605 -10.734 -26.331 1.00 16.07 ? 323 VAL A CA 1 ATOM 2541 C C . VAL A 1 323 ? -28.168 -11.623 -25.182 1.00 15.45 ? 323 VAL A C 1 ATOM 2542 O O . VAL A 1 323 ? -28.886 -11.797 -24.207 1.00 15.25 ? 323 VAL A O 1 ATOM 2543 C CB . VAL A 1 323 ? -28.369 -9.222 -25.963 1.00 15.49 ? 323 VAL A CB 1 ATOM 2544 C CG1 . VAL A 1 323 ? -26.866 -8.936 -25.892 1.00 15.41 ? 323 VAL A CG1 1 ATOM 2545 C CG2 . VAL A 1 323 ? -28.960 -8.306 -27.000 1.00 15.20 ? 323 VAL A CG2 1 ATOM 2546 N N . GLN A 1 324 ? -26.956 -12.181 -25.273 1.00 16.08 ? 324 GLN A N 1 ATOM 2547 C CA . GLN A 1 324 ? -26.444 -12.946 -24.154 1.00 15.49 ? 324 GLN A CA 1 ATOM 2548 C C . GLN A 1 324 ? -25.192 -12.197 -23.697 1.00 16.23 ? 324 GLN A C 1 ATOM 2549 O O . GLN A 1 324 ? -24.404 -11.823 -24.541 1.00 15.82 ? 324 GLN A O 1 ATOM 2550 C CB . GLN A 1 324 ? -26.092 -14.376 -24.622 1.00 17.27 ? 324 GLN A CB 1 ATOM 2551 C CG . GLN A 1 324 ? -25.443 -15.287 -23.537 1.00 15.97 ? 324 GLN A CG 1 ATOM 2552 C CD . GLN A 1 324 ? -26.305 -15.414 -22.275 1.00 16.99 ? 324 GLN A CD 1 ATOM 2553 O OE1 . GLN A 1 324 ? -27.520 -15.657 -22.350 1.00 20.01 ? 324 GLN A OE1 1 ATOM 2554 N NE2 . GLN A 1 324 ? -25.683 -15.269 -21.118 1.00 14.44 ? 324 GLN A NE2 1 ATOM 2555 N N . HIS A 1 325 ? -25.028 -11.976 -22.390 1.00 16.86 ? 325 HIS A N 1 ATOM 2556 C CA . HIS A 1 325 ? -23.827 -11.290 -21.883 1.00 18.64 ? 325 HIS A CA 1 ATOM 2557 C C . HIS A 1 325 ? -22.883 -12.354 -21.309 1.00 17.92 ? 325 HIS A C 1 ATOM 2558 O O . HIS A 1 325 ? -23.312 -13.383 -20.811 1.00 19.77 ? 325 HIS A O 1 ATOM 2559 C CB . HIS A 1 325 ? -24.168 -10.215 -20.822 1.00 19.15 ? 325 HIS A CB 1 ATOM 2560 C CG . HIS A 1 325 ? -24.974 -9.066 -21.348 1.00 19.67 ? 325 HIS A CG 1 ATOM 2561 N ND1 . HIS A 1 325 ? -24.795 -7.775 -20.916 1.00 21.41 ? 325 HIS A ND1 1 ATOM 2562 C CD2 . HIS A 1 325 ? -25.975 -9.019 -22.264 1.00 20.47 ? 325 HIS A CD2 1 ATOM 2563 C CE1 . HIS A 1 325 ? -25.629 -6.977 -21.552 1.00 22.78 ? 325 HIS A CE1 1 ATOM 2564 N NE2 . HIS A 1 325 ? -26.357 -7.709 -22.378 1.00 21.67 ? 325 HIS A NE2 1 ATOM 2565 N N . ALA A 1 326 ? -21.597 -12.127 -21.428 1.00 19.12 ? 326 ALA A N 1 ATOM 2566 C CA . ALA A 1 326 ? -20.638 -13.073 -20.907 1.00 18.77 ? 326 ALA A CA 1 ATOM 2567 C C . ALA A 1 326 ? -19.872 -12.258 -19.876 1.00 18.86 ? 326 ALA A C 1 ATOM 2568 O O . ALA A 1 326 ? -19.178 -11.302 -20.238 1.00 18.63 ? 326 ALA A O 1 ATOM 2569 C CB . ALA A 1 326 ? -19.686 -13.550 -22.030 1.00 18.80 ? 326 ALA A CB 1 ATOM 2570 N N . ASP A 1 327 ? -19.975 -12.667 -18.624 1.00 18.10 ? 327 ASP A N 1 ATOM 2571 C CA . ASP A 1 327 ? -19.338 -11.957 -17.505 1.00 19.38 ? 327 ASP A CA 1 ATOM 2572 C C . ASP A 1 327 ? -17.902 -12.513 -17.348 1.00 19.59 ? 327 ASP A C 1 ATOM 2573 O O . ASP A 1 327 ? -17.472 -13.310 -18.173 1.00 19.12 ? 327 ASP A O 1 ATOM 2574 C CB . ASP A 1 327 ? -20.185 -12.174 -16.253 1.00 20.36 ? 327 ASP A CB 1 ATOM 2575 C CG . ASP A 1 327 ? -20.002 -11.097 -15.213 1.00 22.03 ? 327 ASP A CG 1 ATOM 2576 O OD1 . ASP A 1 327 ? -18.890 -10.532 -15.095 1.00 25.24 ? 327 ASP A OD1 1 ATOM 2577 O OD2 . ASP A 1 327 ? -20.982 -10.842 -14.482 1.00 21.71 ? 327 ASP A OD2 1 ATOM 2578 N N . ILE A 1 328 ? -17.179 -12.129 -16.296 1.00 20.19 ? 328 ILE A N 1 ATOM 2579 C CA . ILE A 1 328 ? -15.719 -12.400 -16.237 1.00 21.61 ? 328 ILE A CA 1 ATOM 2580 C C . ILE A 1 328 ? -15.337 -13.867 -16.151 1.00 22.31 ? 328 ILE A C 1 ATOM 2581 O O . ILE A 1 328 ? -14.147 -14.189 -16.317 1.00 23.92 ? 328 ILE A O 1 ATOM 2582 C CB . ILE A 1 328 ? -15.000 -11.631 -15.069 1.00 21.21 ? 328 ILE A CB 1 ATOM 2583 C CG1 . ILE A 1 328 ? -15.598 -12.025 -13.698 1.00 21.40 ? 328 ILE A CG1 1 ATOM 2584 C CG2 . ILE A 1 328 ? -15.053 -10.129 -15.327 1.00 21.36 ? 328 ILE A CG2 1 ATOM 2585 C CD1 . ILE A 1 328 ? -14.936 -11.300 -12.458 1.00 20.46 ? 328 ILE A CD1 1 ATOM 2586 N N . ASP A 1 329 ? -16.311 -14.754 -15.902 1.00 22.84 ? 329 ASP A N 1 ATOM 2587 C CA . ASP A 1 329 ? -16.022 -16.196 -16.005 1.00 23.67 ? 329 ASP A CA 1 ATOM 2588 C C . ASP A 1 329 ? -15.496 -16.647 -17.395 1.00 22.44 ? 329 ASP A C 1 ATOM 2589 O O . ASP A 1 329 ? -14.818 -17.662 -17.473 1.00 22.76 ? 329 ASP A O 1 ATOM 2590 C CB . ASP A 1 329 ? -17.166 -17.092 -15.475 1.00 24.28 ? 329 ASP A CB 1 ATOM 2591 C CG . ASP A 1 329 ? -18.562 -16.596 -15.842 1.00 27.98 ? 329 ASP A CG 1 ATOM 2592 O OD1 . ASP A 1 329 ? -18.852 -15.383 -15.765 1.00 30.26 ? 329 ASP A OD1 1 ATOM 2593 O OD2 . ASP A 1 329 ? -19.411 -17.450 -16.155 1.00 31.62 ? 329 ASP A OD2 1 ATOM 2594 N N . TYR A 1 330 ? -15.738 -15.891 -18.477 1.00 21.15 ? 330 TYR A N 1 ATOM 2595 C CA . TYR A 1 330 ? -15.278 -16.349 -19.806 1.00 19.64 ? 330 TYR A CA 1 ATOM 2596 C C . TYR A 1 330 ? -13.779 -16.180 -19.916 1.00 20.03 ? 330 TYR A C 1 ATOM 2597 O O . TYR A 1 330 ? -13.118 -16.822 -20.737 1.00 20.58 ? 330 TYR A O 1 ATOM 2598 C CB . TYR A 1 330 ? -15.994 -15.634 -20.973 1.00 19.78 ? 330 TYR A CB 1 ATOM 2599 C CG . TYR A 1 330 ? -15.555 -14.213 -21.252 1.00 19.01 ? 330 TYR A CG 1 ATOM 2600 C CD1 . TYR A 1 330 ? -14.373 -13.939 -21.926 1.00 19.26 ? 330 TYR A CD1 1 ATOM 2601 C CD2 . TYR A 1 330 ? -16.348 -13.144 -20.880 1.00 20.34 ? 330 TYR A CD2 1 ATOM 2602 C CE1 . TYR A 1 330 ? -13.981 -12.659 -22.172 1.00 19.76 ? 330 TYR A CE1 1 ATOM 2603 C CE2 . TYR A 1 330 ? -15.964 -11.849 -21.107 1.00 18.32 ? 330 TYR A CE2 1 ATOM 2604 C CZ . TYR A 1 330 ? -14.753 -11.610 -21.741 1.00 19.30 ? 330 TYR A CZ 1 ATOM 2605 O OH . TYR A 1 330 ? -14.353 -10.336 -22.012 1.00 17.28 ? 330 TYR A OH 1 ATOM 2606 N N . MET A 1 331 ? -13.248 -15.307 -19.088 1.00 18.52 ? 331 MET A N 1 ATOM 2607 C CA . MET A 1 331 ? -11.844 -14.913 -19.201 1.00 19.75 ? 331 MET A CA 1 ATOM 2608 C C . MET A 1 331 ? -10.908 -15.994 -18.669 1.00 19.79 ? 331 MET A C 1 ATOM 2609 O O . MET A 1 331 ? -11.302 -16.853 -17.874 1.00 20.35 ? 331 MET A O 1 ATOM 2610 C CB . MET A 1 331 ? -11.595 -13.626 -18.425 1.00 17.73 ? 331 MET A CB 1 ATOM 2611 C CG . MET A 1 331 ? -12.368 -12.378 -18.974 1.00 19.80 ? 331 MET A CG 1 ATOM 2612 S SD . MET A 1 331 ? -12.133 -10.943 -17.925 1.00 21.94 ? 331 MET A SD 1 ATOM 2613 C CE . MET A 1 331 ? -13.205 -9.746 -18.793 1.00 17.01 ? 331 MET A CE 1 ATOM 2614 N N . ASP A 1 332 ? -9.648 -15.908 -19.082 1.00 21.69 ? 332 ASP A N 1 ATOM 2615 C CA . ASP A 1 332 ? -8.609 -16.752 -18.501 1.00 23.64 ? 332 ASP A CA 1 ATOM 2616 C C . ASP A 1 332 ? -8.128 -16.109 -17.202 1.00 23.30 ? 332 ASP A C 1 ATOM 2617 O O . ASP A 1 332 ? -7.316 -15.171 -17.214 1.00 22.85 ? 332 ASP A O 1 ATOM 2618 C CB . ASP A 1 332 ? -7.449 -16.909 -19.482 1.00 24.05 ? 332 ASP A CB 1 ATOM 2619 C CG . ASP A 1 332 ? -6.439 -17.958 -19.023 1.00 29.73 ? 332 ASP A CG 1 ATOM 2620 O OD1 . ASP A 1 332 ? -6.643 -18.557 -17.946 1.00 32.50 ? 332 ASP A OD1 1 ATOM 2621 O OD2 . ASP A 1 332 ? -5.462 -18.174 -19.763 1.00 35.14 ? 332 ASP A OD2 1 ATOM 2622 N N . GLU A 1 333 ? -8.642 -16.608 -16.081 1.00 23.65 ? 333 GLU A N 1 ATOM 2623 C CA . GLU A 1 333 ? -8.291 -16.089 -14.741 1.00 24.45 ? 333 GLU A CA 1 ATOM 2624 C C . GLU A 1 333 ? -8.642 -14.596 -14.590 1.00 23.57 ? 333 GLU A C 1 ATOM 2625 O O . GLU A 1 333 ? -7.867 -13.786 -14.042 1.00 21.72 ? 333 GLU A O 1 ATOM 2626 C CB . GLU A 1 333 ? -6.809 -16.361 -14.398 1.00 25.67 ? 333 GLU A CB 1 ATOM 2627 C CG . GLU A 1 333 ? -6.389 -17.857 -14.528 1.00 32.13 ? 333 GLU A CG 1 ATOM 2628 C CD . GLU A 1 333 ? -6.924 -18.775 -13.400 1.00 39.77 ? 333 GLU A CD 1 ATOM 2629 O OE1 . GLU A 1 333 ? -7.569 -18.291 -12.426 1.00 40.66 ? 333 GLU A OE1 1 ATOM 2630 O OE2 . GLU A 1 333 ? -6.673 -20.008 -13.489 1.00 43.54 ? 333 GLU A OE2 1 ATOM 2631 N N . ARG A 1 334 ? -9.825 -14.251 -15.103 1.00 22.72 ? 334 ARG A N 1 ATOM 2632 C CA . ARG A 1 334 ? -10.394 -12.940 -14.954 1.00 23.07 ? 334 ARG A CA 1 ATOM 2633 C C . ARG A 1 334 ? -9.578 -11.821 -15.596 1.00 22.48 ? 334 ARG A C 1 ATOM 2634 O O . ARG A 1 334 ? -9.630 -10.688 -15.155 1.00 23.84 ? 334 ARG A O 1 ATOM 2635 C CB . ARG A 1 334 ? -10.709 -12.678 -13.480 1.00 23.02 ? 334 ARG A CB 1 ATOM 2636 C CG . ARG A 1 334 ? -11.828 -13.602 -12.989 1.00 24.73 ? 334 ARG A CG 1 ATOM 2637 C CD . ARG A 1 334 ? -12.054 -13.610 -11.461 1.00 25.26 ? 334 ARG A CD 1 ATOM 2638 N NE . ARG A 1 334 ? -13.302 -14.326 -11.157 1.00 29.15 ? 334 ARG A NE 1 ATOM 2639 C CZ . ARG A 1 334 ? -13.934 -14.288 -9.987 1.00 33.20 ? 334 ARG A CZ 1 ATOM 2640 N NH1 . ARG A 1 334 ? -13.439 -13.559 -8.981 1.00 35.06 ? 334 ARG A NH1 1 ATOM 2641 N NH2 . ARG A 1 334 ? -15.061 -14.962 -9.824 1.00 32.79 ? 334 ARG A NH2 1 ATOM 2642 N N . ARG A 1 335 ? -8.850 -12.131 -16.657 1.00 21.38 ? 335 ARG A N 1 ATOM 2643 C CA . ARG A 1 335 ? -8.091 -11.114 -17.364 1.00 21.09 ? 335 ARG A CA 1 ATOM 2644 C C . ARG A 1 335 ? -8.680 -10.743 -18.694 1.00 21.25 ? 335 ARG A C 1 ATOM 2645 O O . ARG A 1 335 ? -9.045 -11.637 -19.464 1.00 22.09 ? 335 ARG A O 1 ATOM 2646 C CB . ARG A 1 335 ? -6.688 -11.636 -17.622 1.00 21.77 ? 335 ARG A CB 1 ATOM 2647 C CG . ARG A 1 335 ? -5.932 -11.803 -16.323 1.00 22.26 ? 335 ARG A CG 1 ATOM 2648 C CD . ARG A 1 335 ? -4.547 -12.334 -16.576 1.00 26.80 ? 335 ARG A CD 1 ATOM 2649 N NE . ARG A 1 335 ? -4.646 -13.656 -17.193 1.00 29.67 ? 335 ARG A NE 1 ATOM 2650 C CZ . ARG A 1 335 ? -3.629 -14.279 -17.774 1.00 35.06 ? 335 ARG A CZ 1 ATOM 2651 N NH1 . ARG A 1 335 ? -2.433 -13.699 -17.806 1.00 33.13 ? 335 ARG A NH1 1 ATOM 2652 N NH2 . ARG A 1 335 ? -3.808 -15.482 -18.320 1.00 35.53 ? 335 ARG A NH2 1 ATOM 2653 N N . ASP A 1 336 ? -8.732 -9.436 -18.984 1.00 21.52 ? 336 ASP A N 1 ATOM 2654 C CA . ASP A 1 336 ? -9.341 -8.935 -20.229 1.00 21.86 ? 336 ASP A CA 1 ATOM 2655 C C . ASP A 1 336 ? -8.611 -9.528 -21.412 1.00 22.29 ? 336 ASP A C 1 ATOM 2656 O O . ASP A 1 336 ? -7.393 -9.763 -21.348 1.00 22.10 ? 336 ASP A O 1 ATOM 2657 C CB . ASP A 1 336 ? -9.171 -7.434 -20.373 1.00 21.45 ? 336 ASP A CB 1 ATOM 2658 C CG . ASP A 1 336 ? -10.088 -6.621 -19.490 1.00 22.83 ? 336 ASP A CG 1 ATOM 2659 O OD1 . ASP A 1 336 ? -11.161 -7.098 -19.037 1.00 22.87 ? 336 ASP A OD1 1 ATOM 2660 O OD2 . ASP A 1 336 ? -9.734 -5.437 -19.306 1.00 27.32 ? 336 ASP A OD2 1 ATOM 2661 N N . PHE A 1 337 ? -9.356 -9.723 -22.498 1.00 21.27 ? 337 PHE A N 1 ATOM 2662 C CA . PHE A 1 337 ? -8.806 -10.061 -23.821 1.00 21.57 ? 337 PHE A CA 1 ATOM 2663 C C . PHE A 1 337 ? -8.176 -11.455 -23.872 1.00 21.95 ? 337 PHE A C 1 ATOM 2664 O O . PHE A 1 337 ? -7.272 -11.697 -24.660 1.00 22.43 ? 337 PHE A O 1 ATOM 2665 C CB . PHE A 1 337 ? -7.830 -9.001 -24.346 1.00 21.43 ? 337 PHE A CB 1 ATOM 2666 C CG . PHE A 1 337 ? -8.341 -7.593 -24.228 1.00 21.32 ? 337 PHE A CG 1 ATOM 2667 C CD1 . PHE A 1 337 ? -9.517 -7.202 -24.893 1.00 20.36 ? 337 PHE A CD1 1 ATOM 2668 C CD2 . PHE A 1 337 ? -7.701 -6.674 -23.392 1.00 19.20 ? 337 PHE A CD2 1 ATOM 2669 C CE1 . PHE A 1 337 ? -9.979 -5.888 -24.763 1.00 19.15 ? 337 PHE A CE1 1 ATOM 2670 C CE2 . PHE A 1 337 ? -8.181 -5.359 -23.244 1.00 20.03 ? 337 PHE A CE2 1 ATOM 2671 C CZ . PHE A 1 337 ? -9.330 -4.985 -23.936 1.00 19.46 ? 337 PHE A CZ 1 ATOM 2672 N N . THR A 1 338 ? -8.730 -12.359 -23.068 1.00 22.07 ? 338 THR A N 1 ATOM 2673 C CA . THR A 1 338 ? -8.454 -13.777 -23.098 1.00 22.00 ? 338 THR A CA 1 ATOM 2674 C C . THR A 1 338 ? -9.770 -14.525 -22.910 1.00 22.77 ? 338 THR A C 1 ATOM 2675 O O . THR A 1 338 ? -10.753 -13.952 -22.431 1.00 22.06 ? 338 THR A O 1 ATOM 2676 C CB . THR A 1 338 ? -7.541 -14.153 -21.919 1.00 22.74 ? 338 THR A CB 1 ATOM 2677 O OG1 . THR A 1 338 ? -8.240 -14.004 -20.674 1.00 22.06 ? 338 THR A OG1 1 ATOM 2678 C CG2 . THR A 1 338 ? -6.252 -13.284 -21.919 1.00 20.39 ? 338 THR A CG2 1 ATOM 2679 N N . TYR A 1 339 ? -9.804 -15.802 -23.250 1.00 22.07 ? 339 TYR A N 1 ATOM 2680 C CA . TYR A 1 339 ? -10.865 -16.635 -22.714 1.00 23.66 ? 339 TYR A CA 1 ATOM 2681 C C . TYR A 1 339 ? -10.239 -17.903 -22.144 1.00 24.46 ? 339 TYR A C 1 ATOM 2682 O O . TYR A 1 339 ? -9.100 -18.250 -22.502 1.00 23.89 ? 339 TYR A O 1 ATOM 2683 C CB . TYR A 1 339 ? -11.963 -16.902 -23.750 1.00 24.74 ? 339 TYR A CB 1 ATOM 2684 C CG . TYR A 1 339 ? -11.598 -17.771 -24.946 1.00 24.68 ? 339 TYR A CG 1 ATOM 2685 C CD1 . TYR A 1 339 ? -11.744 -19.156 -24.887 1.00 25.43 ? 339 TYR A CD1 1 ATOM 2686 C CD2 . TYR A 1 339 ? -11.162 -17.204 -26.144 1.00 27.09 ? 339 TYR A CD2 1 ATOM 2687 C CE1 . TYR A 1 339 ? -11.436 -19.960 -25.982 1.00 26.30 ? 339 TYR A CE1 1 ATOM 2688 C CE2 . TYR A 1 339 ? -10.844 -18.004 -27.249 1.00 26.71 ? 339 TYR A CE2 1 ATOM 2689 C CZ . TYR A 1 339 ? -10.998 -19.371 -27.152 1.00 27.17 ? 339 TYR A CZ 1 ATOM 2690 O OH . TYR A 1 339 ? -10.687 -20.171 -28.222 1.00 29.70 ? 339 TYR A OH 1 ATOM 2691 N N . ASP A 1 340 ? -10.965 -18.552 -21.239 1.00 24.27 ? 340 ASP A N 1 ATOM 2692 C CA . ASP A 1 340 ? -10.506 -19.731 -20.542 1.00 25.94 ? 340 ASP A CA 1 ATOM 2693 C C . ASP A 1 340 ? -10.595 -20.918 -21.499 1.00 26.08 ? 340 ASP A C 1 ATOM 2694 O O . ASP A 1 340 ? -11.682 -21.432 -21.788 1.00 25.69 ? 340 ASP A O 1 ATOM 2695 C CB . ASP A 1 340 ? -11.389 -19.946 -19.323 1.00 26.01 ? 340 ASP A CB 1 ATOM 2696 C CG . ASP A 1 340 ? -10.904 -21.071 -18.411 1.00 29.00 ? 340 ASP A CG 1 ATOM 2697 O OD1 . ASP A 1 340 ? -10.228 -22.020 -18.872 1.00 29.27 ? 340 ASP A OD1 1 ATOM 2698 O OD2 . ASP A 1 340 ? -11.264 -21.024 -17.224 1.00 30.51 ? 340 ASP A OD2 1 ATOM 2699 N N . SER A 1 341 ? -9.433 -21.365 -21.963 1.00 26.78 ? 341 SER A N 1 ATOM 2700 C CA . SER A 1 341 ? -9.333 -22.423 -22.970 1.00 27.77 ? 341 SER A CA 1 ATOM 2701 C C . SER A 1 341 ? -9.790 -23.791 -22.479 1.00 27.61 ? 341 SER A C 1 ATOM 2702 O O . SER A 1 341 ? -9.979 -24.684 -23.286 1.00 29.22 ? 341 SER A O 1 ATOM 2703 C CB . SER A 1 341 ? -7.883 -22.517 -23.439 1.00 28.51 ? 341 SER A CB 1 ATOM 2704 O OG . SER A 1 341 ? -7.095 -22.916 -22.319 1.00 31.68 ? 341 SER A OG 1 ATOM 2705 N N . VAL A 1 342 ? -9.981 -23.968 -21.172 1.00 27.80 ? 342 VAL A N 1 ATOM 2706 C CA . VAL A 1 342 ? -10.578 -25.200 -20.620 1.00 27.50 ? 342 VAL A CA 1 ATOM 2707 C C . VAL A 1 342 ? -12.075 -25.061 -20.370 1.00 26.55 ? 342 VAL A C 1 ATOM 2708 O O . VAL A 1 342 ? -12.876 -25.771 -20.977 1.00 27.03 ? 342 VAL A O 1 ATOM 2709 C CB . VAL A 1 342 ? -9.840 -25.672 -19.322 1.00 27.97 ? 342 VAL A CB 1 ATOM 2710 C CG1 . VAL A 1 342 ? -10.544 -26.852 -18.663 1.00 26.70 ? 342 VAL A CG1 1 ATOM 2711 C CG2 . VAL A 1 342 ? -8.402 -26.041 -19.666 1.00 29.85 ? 342 VAL A CG2 1 ATOM 2712 N N . ASP A 1 343 ? -12.469 -24.159 -19.475 1.00 25.25 ? 343 ASP A N 1 ATOM 2713 C CA . ASP A 1 343 ? -13.896 -24.032 -19.141 1.00 24.62 ? 343 ASP A CA 1 ATOM 2714 C C . ASP A 1 343 ? -14.713 -23.369 -20.237 1.00 23.35 ? 343 ASP A C 1 ATOM 2715 O O . ASP A 1 343 ? -15.932 -23.553 -20.281 1.00 22.57 ? 343 ASP A O 1 ATOM 2716 C CB . ASP A 1 343 ? -14.079 -23.250 -17.846 1.00 25.06 ? 343 ASP A CB 1 ATOM 2717 C CG . ASP A 1 343 ? -13.693 -24.057 -16.616 1.00 28.04 ? 343 ASP A CG 1 ATOM 2718 O OD1 . ASP A 1 343 ? -13.399 -25.262 -16.748 1.00 31.51 ? 343 ASP A OD1 1 ATOM 2719 O OD2 . ASP A 1 343 ? -13.708 -23.477 -15.518 1.00 31.11 ? 343 ASP A OD2 1 ATOM 2720 N N . PHE A 1 344 ? -14.062 -22.547 -21.049 1.00 22.84 ? 344 PHE A N 1 ATOM 2721 C CA . PHE A 1 344 ? -14.725 -21.879 -22.187 1.00 23.44 ? 344 PHE A CA 1 ATOM 2722 C C . PHE A 1 344 ? -14.099 -22.344 -23.508 1.00 23.74 ? 344 PHE A C 1 ATOM 2723 O O . PHE A 1 344 ? -13.980 -21.588 -24.464 1.00 22.64 ? 344 PHE A O 1 ATOM 2724 C CB . PHE A 1 344 ? -14.792 -20.345 -22.022 1.00 22.66 ? 344 PHE A CB 1 ATOM 2725 C CG . PHE A 1 344 ? -15.918 -19.894 -21.097 1.00 25.20 ? 344 PHE A CG 1 ATOM 2726 C CD1 . PHE A 1 344 ? -15.815 -20.037 -19.698 1.00 25.12 ? 344 PHE A CD1 1 ATOM 2727 C CD2 . PHE A 1 344 ? -17.120 -19.392 -21.634 1.00 23.98 ? 344 PHE A CD2 1 ATOM 2728 C CE1 . PHE A 1 344 ? -16.909 -19.667 -18.849 1.00 23.93 ? 344 PHE A CE1 1 ATOM 2729 C CE2 . PHE A 1 344 ? -18.199 -19.016 -20.796 1.00 23.33 ? 344 PHE A CE2 1 ATOM 2730 C CZ . PHE A 1 344 ? -18.091 -19.154 -19.417 1.00 25.30 ? 344 PHE A CZ 1 ATOM 2731 N N . LYS A 1 345 ? -13.724 -23.623 -23.554 1.00 25.89 ? 345 LYS A N 1 ATOM 2732 C CA . LYS A 1 345 ? -13.177 -24.221 -24.789 1.00 27.50 ? 345 LYS A CA 1 ATOM 2733 C C . LYS A 1 345 ? -14.323 -24.259 -25.768 1.00 26.83 ? 345 LYS A C 1 ATOM 2734 O O . LYS A 1 345 ? -15.414 -24.720 -25.435 1.00 27.60 ? 345 LYS A O 1 ATOM 2735 C CB . LYS A 1 345 ? -12.679 -25.645 -24.542 1.00 28.39 ? 345 LYS A CB 1 ATOM 2736 C CG . LYS A 1 345 ? -11.996 -26.297 -25.778 1.00 30.59 ? 345 LYS A CG 1 ATOM 2737 C CD . LYS A 1 345 ? -11.740 -27.817 -25.533 1.00 30.51 ? 345 LYS A CD 1 ATOM 2738 C CE . LYS A 1 345 ? -10.882 -28.453 -26.646 1.00 35.36 ? 345 LYS A CE 1 ATOM 2739 N NZ . LYS A 1 345 ? -11.175 -29.920 -26.709 1.00 39.71 ? 345 LYS A NZ 1 ATOM 2740 N N . GLY A 1 346 ? -14.094 -23.738 -26.953 1.00 27.23 ? 346 GLY A N 1 ATOM 2741 C CA . GLY A 1 346 ? -15.147 -23.685 -27.966 1.00 27.02 ? 346 GLY A CA 1 ATOM 2742 C C . GLY A 1 346 ? -16.002 -22.433 -27.932 1.00 26.93 ? 346 GLY A C 1 ATOM 2743 O O . GLY A 1 346 ? -17.048 -22.381 -28.579 1.00 26.48 ? 346 GLY A O 1 ATOM 2744 N N . PHE A 1 347 ? -15.557 -21.425 -27.177 1.00 26.22 ? 347 PHE A N 1 ATOM 2745 C CA . PHE A 1 347 ? -16.196 -20.098 -27.163 1.00 25.73 ? 347 PHE A CA 1 ATOM 2746 C C . PHE A 1 347 ? -16.496 -19.546 -28.594 1.00 25.05 ? 347 PHE A C 1 ATOM 2747 O O . PHE A 1 347 ? -17.641 -19.136 -28.846 1.00 25.19 ? 347 PHE A O 1 ATOM 2748 C CB . PHE A 1 347 ? -15.369 -19.121 -26.290 1.00 25.93 ? 347 PHE A CB 1 ATOM 2749 C CG . PHE A 1 347 ? -16.153 -17.963 -25.715 1.00 25.92 ? 347 PHE A CG 1 ATOM 2750 C CD1 . PHE A 1 347 ? -17.546 -18.037 -25.522 1.00 28.24 ? 347 PHE A CD1 1 ATOM 2751 C CD2 . PHE A 1 347 ? -15.486 -16.816 -25.303 1.00 27.59 ? 347 PHE A CD2 1 ATOM 2752 C CE1 . PHE A 1 347 ? -18.248 -16.961 -24.968 1.00 26.48 ? 347 PHE A CE1 1 ATOM 2753 C CE2 . PHE A 1 347 ? -16.178 -15.736 -24.763 1.00 26.86 ? 347 PHE A CE2 1 ATOM 2754 C CZ . PHE A 1 347 ? -17.565 -15.816 -24.598 1.00 26.10 ? 347 PHE A CZ 1 ATOM 2755 N N . PRO A 1 348 ? -15.503 -19.579 -29.540 1.00 24.70 ? 348 PRO A N 1 ATOM 2756 C CA . PRO A 1 348 ? -15.767 -19.135 -30.907 1.00 24.39 ? 348 PRO A CA 1 ATOM 2757 C C . PRO A 1 348 ? -16.871 -19.910 -31.599 1.00 24.27 ? 348 PRO A C 1 ATOM 2758 O O . PRO A 1 348 ? -17.648 -19.299 -32.334 1.00 24.31 ? 348 PRO A O 1 ATOM 2759 C CB . PRO A 1 348 ? -14.409 -19.332 -31.607 1.00 24.21 ? 348 PRO A CB 1 ATOM 2760 C CG . PRO A 1 348 ? -13.442 -19.158 -30.475 1.00 23.65 ? 348 PRO A CG 1 ATOM 2761 C CD . PRO A 1 348 ? -14.087 -19.975 -29.423 1.00 24.63 ? 348 PRO A CD 1 ATOM 2762 N N . GLU A 1 349 ? -17.002 -21.207 -31.316 1.00 23.23 ? 349 GLU A N 1 ATOM 2763 C CA . GLU A 1 349 ? -18.085 -21.987 -31.924 1.00 24.93 ? 349 GLU A CA 1 ATOM 2764 C C . GLU A 1 349 ? -19.450 -21.584 -31.336 1.00 23.89 ? 349 GLU A C 1 ATOM 2765 O O . GLU A 1 349 ? -20.471 -21.560 -32.026 1.00 21.74 ? 349 GLU A O 1 ATOM 2766 C CB . GLU A 1 349 ? -17.881 -23.496 -31.726 1.00 24.92 ? 349 GLU A CB 1 ATOM 2767 C CG . GLU A 1 349 ? -16.638 -24.099 -32.419 1.00 28.79 ? 349 GLU A CG 1 ATOM 2768 C CD . GLU A 1 349 ? -16.084 -25.331 -31.688 1.00 30.24 ? 349 GLU A CD 1 ATOM 2769 O OE1 . GLU A 1 349 ? -16.896 -26.252 -31.397 1.00 35.73 ? 349 GLU A OE1 1 ATOM 2770 O OE2 . GLU A 1 349 ? -14.839 -25.379 -31.438 1.00 33.44 ? 349 GLU A OE2 1 ATOM 2771 N N . PHE A 1 350 ? -19.446 -21.289 -30.047 1.00 23.23 ? 350 PHE A N 1 ATOM 2772 C CA . PHE A 1 350 ? -20.657 -20.817 -29.350 1.00 22.26 ? 350 PHE A CA 1 ATOM 2773 C C . PHE A 1 350 ? -21.106 -19.463 -29.884 1.00 21.59 ? 350 PHE A C 1 ATOM 2774 O O . PHE A 1 350 ? -22.318 -19.206 -30.043 1.00 20.97 ? 350 PHE A O 1 ATOM 2775 C CB . PHE A 1 350 ? -20.405 -20.733 -27.837 1.00 22.66 ? 350 PHE A CB 1 ATOM 2776 C CG . PHE A 1 350 ? -21.504 -20.001 -27.067 1.00 23.20 ? 350 PHE A CG 1 ATOM 2777 C CD1 . PHE A 1 350 ? -22.719 -20.627 -26.812 1.00 23.90 ? 350 PHE A CD1 1 ATOM 2778 C CD2 . PHE A 1 350 ? -21.292 -18.716 -26.584 1.00 23.06 ? 350 PHE A CD2 1 ATOM 2779 C CE1 . PHE A 1 350 ? -23.742 -19.970 -26.092 1.00 24.86 ? 350 PHE A CE1 1 ATOM 2780 C CE2 . PHE A 1 350 ? -22.295 -18.051 -25.852 1.00 23.12 ? 350 PHE A CE2 1 ATOM 2781 C CZ . PHE A 1 350 ? -23.529 -18.699 -25.609 1.00 23.82 ? 350 PHE A CZ 1 ATOM 2782 N N . VAL A 1 351 ? -20.153 -18.586 -30.155 1.00 20.03 ? 351 VAL A N 1 ATOM 2783 C CA . VAL A 1 351 ? -20.449 -17.294 -30.792 1.00 21.46 ? 351 VAL A CA 1 ATOM 2784 C C . VAL A 1 351 ? -21.192 -17.475 -32.142 1.00 21.35 ? 351 VAL A C 1 ATOM 2785 O O . VAL A 1 351 ? -22.229 -16.835 -32.392 1.00 20.83 ? 351 VAL A O 1 ATOM 2786 C CB . VAL A 1 351 ? -19.178 -16.426 -30.871 1.00 21.67 ? 351 VAL A CB 1 ATOM 2787 C CG1 . VAL A 1 351 ? -19.432 -15.117 -31.616 1.00 23.03 ? 351 VAL A CG1 1 ATOM 2788 C CG2 . VAL A 1 351 ? -18.748 -16.105 -29.468 1.00 22.06 ? 351 VAL A CG2 1 ATOM 2789 N N . ASN A 1 352 ? -20.711 -18.422 -32.950 1.00 21.00 ? 352 ASN A N 1 ATOM 2790 C CA . ASN A 1 352 ? -21.364 -18.757 -34.217 1.00 20.56 ? 352 ASN A CA 1 ATOM 2791 C C . ASN A 1 352 ? -22.773 -19.258 -34.000 1.00 19.95 ? 352 ASN A C 1 ATOM 2792 O O . ASN A 1 352 ? -23.659 -18.916 -34.777 1.00 18.45 ? 352 ASN A O 1 ATOM 2793 C CB . ASN A 1 352 ? -20.595 -19.842 -34.954 1.00 20.88 ? 352 ASN A CB 1 ATOM 2794 C CG . ASN A 1 352 ? -19.348 -19.322 -35.617 1.00 22.92 ? 352 ASN A CG 1 ATOM 2795 O OD1 . ASN A 1 352 ? -19.008 -18.160 -35.498 1.00 23.53 ? 352 ASN A OD1 1 ATOM 2796 N ND2 . ASN A 1 352 ? -18.679 -20.184 -36.355 1.00 25.21 ? 352 ASN A ND2 1 ATOM 2797 N N . GLU A 1 353 ? -22.958 -20.108 -32.994 1.00 20.06 ? 353 GLU A N 1 ATOM 2798 C CA . GLU A 1 353 ? -24.303 -20.608 -32.647 1.00 22.20 ? 353 GLU A CA 1 ATOM 2799 C C . GLU A 1 353 ? -25.210 -19.434 -32.292 1.00 21.25 ? 353 GLU A C 1 ATOM 2800 O O . GLU A 1 353 ? -26.349 -19.397 -32.742 1.00 20.86 ? 353 GLU A O 1 ATOM 2801 C CB . GLU A 1 353 ? -24.286 -21.604 -31.470 1.00 21.08 ? 353 GLU A CB 1 ATOM 2802 C CG . GLU A 1 353 ? -23.652 -22.925 -31.821 1.00 26.70 ? 353 GLU A CG 1 ATOM 2803 C CD . GLU A 1 353 ? -23.178 -23.777 -30.623 1.00 28.04 ? 353 GLU A CD 1 ATOM 2804 O OE1 . GLU A 1 353 ? -23.097 -23.302 -29.446 1.00 32.82 ? 353 GLU A OE1 1 ATOM 2805 O OE2 . GLU A 1 353 ? -22.847 -24.947 -30.907 1.00 33.72 ? 353 GLU A OE2 1 ATOM 2806 N N . LEU A 1 354 ? -24.725 -18.507 -31.456 1.00 19.79 ? 354 LEU A N 1 ATOM 2807 C CA . LEU A 1 354 ? -25.539 -17.341 -31.106 1.00 19.54 ? 354 LEU A CA 1 ATOM 2808 C C . LEU A 1 354 ? -25.933 -16.613 -32.378 1.00 19.63 ? 354 LEU A C 1 ATOM 2809 O O . LEU A 1 354 ? -27.136 -16.347 -32.620 1.00 18.11 ? 354 LEU A O 1 ATOM 2810 C CB . LEU A 1 354 ? -24.793 -16.378 -30.159 1.00 19.57 ? 354 LEU A CB 1 ATOM 2811 C CG . LEU A 1 354 ? -24.691 -16.743 -28.670 1.00 19.88 ? 354 LEU A CG 1 ATOM 2812 C CD1 . LEU A 1 354 ? -23.873 -15.613 -28.018 1.00 17.96 ? 354 LEU A CD1 1 ATOM 2813 C CD2 . LEU A 1 354 ? -26.068 -16.894 -27.969 1.00 21.06 ? 354 LEU A CD2 1 ATOM 2814 N N . HIS A 1 355 ? -24.939 -16.357 -33.223 1.00 18.30 ? 355 HIS A N 1 ATOM 2815 C CA . HIS A 1 355 ? -25.165 -15.588 -34.432 1.00 20.52 ? 355 HIS A CA 1 ATOM 2816 C C . HIS A 1 355 ? -26.136 -16.262 -35.396 1.00 21.13 ? 355 HIS A C 1 ATOM 2817 O O . HIS A 1 355 ? -27.004 -15.610 -35.951 1.00 20.47 ? 355 HIS A O 1 ATOM 2818 C CB . HIS A 1 355 ? -23.844 -15.224 -35.097 1.00 20.60 ? 355 HIS A CB 1 ATOM 2819 C CG . HIS A 1 355 ? -23.062 -14.192 -34.328 1.00 21.75 ? 355 HIS A CG 1 ATOM 2820 N ND1 . HIS A 1 355 ? -21.720 -13.960 -34.541 1.00 21.25 ? 355 HIS A ND1 1 ATOM 2821 C CD2 . HIS A 1 355 ? -23.442 -13.320 -33.356 1.00 19.54 ? 355 HIS A CD2 1 ATOM 2822 C CE1 . HIS A 1 355 ? -21.309 -12.990 -33.738 1.00 20.79 ? 355 HIS A CE1 1 ATOM 2823 N NE2 . HIS A 1 355 ? -22.322 -12.609 -32.989 1.00 22.70 ? 355 HIS A NE2 1 ATOM 2824 N N . ASN A 1 356 ? -25.974 -17.567 -35.573 1.00 21.45 ? 356 ASN A N 1 ATOM 2825 C CA . ASN A 1 356 ? -26.884 -18.364 -36.399 1.00 22.42 ? 356 ASN A CA 1 ATOM 2826 C C . ASN A 1 356 ? -28.319 -18.361 -35.873 1.00 23.13 ? 356 ASN A C 1 ATOM 2827 O O . ASN A 1 356 ? -29.271 -18.624 -36.622 1.00 22.85 ? 356 ASN A O 1 ATOM 2828 C CB . ASN A 1 356 ? -26.384 -19.818 -36.450 1.00 23.10 ? 356 ASN A CB 1 ATOM 2829 C CG . ASN A 1 356 ? -27.143 -20.641 -37.458 1.00 25.18 ? 356 ASN A CG 1 ATOM 2830 O OD1 . ASN A 1 356 ? -27.431 -20.156 -38.540 1.00 28.73 ? 356 ASN A OD1 1 ATOM 2831 N ND2 . ASN A 1 356 ? -27.515 -21.863 -37.095 1.00 26.31 ? 356 ASN A ND2 1 ATOM 2832 N N . ASN A 1 357 ? -28.473 -18.120 -34.577 1.00 22.49 ? 357 ASN A N 1 ATOM 2833 C CA . ASN A 1 357 ? -29.814 -18.057 -33.976 1.00 23.23 ? 357 ASN A CA 1 ATOM 2834 C C . ASN A 1 357 ? -30.380 -16.641 -33.943 1.00 22.49 ? 357 ASN A C 1 ATOM 2835 O O . ASN A 1 357 ? -31.460 -16.386 -33.362 1.00 22.24 ? 357 ASN A O 1 ATOM 2836 C CB . ASN A 1 357 ? -29.785 -18.680 -32.581 1.00 24.12 ? 357 ASN A CB 1 ATOM 2837 C CG . ASN A 1 357 ? -29.486 -20.196 -32.619 1.00 28.20 ? 357 ASN A CG 1 ATOM 2838 O OD1 . ASN A 1 357 ? -28.738 -20.690 -31.811 1.00 35.03 ? 357 ASN A OD1 1 ATOM 2839 N ND2 . ASN A 1 357 ? -30.068 -20.911 -33.562 1.00 31.32 ? 357 ASN A ND2 1 ATOM 2840 N N . GLY A 1 358 ? -29.651 -15.718 -34.557 1.00 21.32 ? 358 GLY A N 1 ATOM 2841 C CA . GLY A 1 358 ? -30.076 -14.329 -34.643 1.00 21.05 ? 358 GLY A CA 1 ATOM 2842 C C . GLY A 1 358 ? -29.736 -13.519 -33.401 1.00 20.00 ? 358 GLY A C 1 ATOM 2843 O O . GLY A 1 358 ? -30.133 -12.371 -33.272 1.00 20.51 ? 358 GLY A O 1 ATOM 2844 N N . GLN A 1 359 ? -28.923 -14.083 -32.520 1.00 18.99 ? 359 GLN A N 1 ATOM 2845 C CA . GLN A 1 359 ? -28.610 -13.413 -31.279 1.00 17.97 ? 359 GLN A CA 1 ATOM 2846 C C . GLN A 1 359 ? -27.237 -12.740 -31.273 1.00 17.90 ? 359 GLN A C 1 ATOM 2847 O O . GLN A 1 359 ? -26.406 -12.934 -32.170 1.00 18.08 ? 359 GLN A O 1 ATOM 2848 C CB . GLN A 1 359 ? -28.686 -14.426 -30.153 1.00 17.66 ? 359 GLN A CB 1 ATOM 2849 C CG . GLN A 1 359 ? -30.086 -14.956 -29.924 1.00 20.51 ? 359 GLN A CG 1 ATOM 2850 C CD . GLN A 1 359 ? -30.062 -16.115 -28.971 1.00 22.83 ? 359 GLN A CD 1 ATOM 2851 O OE1 . GLN A 1 359 ? -29.422 -17.130 -29.239 1.00 24.32 ? 359 GLN A OE1 1 ATOM 2852 N NE2 . GLN A 1 359 ? -30.749 -15.973 -27.839 1.00 20.74 ? 359 GLN A NE2 1 ATOM 2853 N N . LYS A 1 360 ? -27.001 -11.949 -30.222 1.00 17.76 ? 360 LYS A N 1 ATOM 2854 C CA . LYS A 1 360 ? -25.791 -11.143 -30.098 1.00 17.61 ? 360 LYS A CA 1 ATOM 2855 C C . LYS A 1 360 ? -25.074 -11.493 -28.809 1.00 17.90 ? 360 LYS A C 1 ATOM 2856 O O . LYS A 1 360 ? -25.689 -11.902 -27.829 1.00 17.55 ? 360 LYS A O 1 ATOM 2857 C CB . LYS A 1 360 ? -26.133 -9.648 -30.117 1.00 18.64 ? 360 LYS A CB 1 ATOM 2858 C CG . LYS A 1 360 ? -26.959 -9.209 -31.364 1.00 19.36 ? 360 LYS A CG 1 ATOM 2859 C CD . LYS A 1 360 ? -26.113 -9.210 -32.646 1.00 19.93 ? 360 LYS A CD 1 ATOM 2860 C CE . LYS A 1 360 ? -26.952 -8.905 -33.898 1.00 25.71 ? 360 LYS A CE 1 ATOM 2861 N NZ . LYS A 1 360 ? -26.117 -8.507 -35.085 1.00 31.50 ? 360 LYS A NZ 1 ATOM 2862 N N . LEU A 1 361 ? -23.761 -11.340 -28.834 1.00 17.92 ? 361 LEU A N 1 ATOM 2863 C CA . LEU A 1 361 ? -22.932 -11.577 -27.657 1.00 18.08 ? 361 LEU A CA 1 ATOM 2864 C C . LEU A 1 361 ? -22.388 -10.238 -27.190 1.00 16.65 ? 361 LEU A C 1 ATOM 2865 O O . LEU A 1 361 ? -21.816 -9.484 -27.964 1.00 17.92 ? 361 LEU A O 1 ATOM 2866 C CB . LEU A 1 361 ? -21.757 -12.527 -27.976 1.00 18.08 ? 361 LEU A CB 1 ATOM 2867 C CG . LEU A 1 361 ? -20.738 -12.588 -26.823 1.00 18.82 ? 361 LEU A CG 1 ATOM 2868 C CD1 . LEU A 1 361 ? -21.329 -13.331 -25.626 1.00 18.51 ? 361 LEU A CD1 1 ATOM 2869 C CD2 . LEU A 1 361 ? -19.403 -13.219 -27.294 1.00 18.93 ? 361 LEU A CD2 1 ATOM 2870 N N . VAL A 1 362 ? -22.603 -9.930 -25.929 1.00 16.88 ? 362 VAL A N 1 ATOM 2871 C CA . VAL A 1 362 ? -21.979 -8.781 -25.313 1.00 16.69 ? 362 VAL A CA 1 ATOM 2872 C C . VAL A 1 362 ? -20.977 -9.301 -24.272 1.00 16.23 ? 362 VAL A C 1 ATOM 2873 O O . VAL A 1 362 ? -21.333 -10.114 -23.424 1.00 17.04 ? 362 VAL A O 1 ATOM 2874 C CB . VAL A 1 362 ? -23.035 -7.857 -24.654 1.00 16.74 ? 362 VAL A CB 1 ATOM 2875 C CG1 . VAL A 1 362 ? -22.352 -6.839 -23.736 1.00 15.51 ? 362 VAL A CG1 1 ATOM 2876 C CG2 . VAL A 1 362 ? -23.861 -7.158 -25.734 1.00 14.37 ? 362 VAL A CG2 1 ATOM 2877 N N . ILE A 1 363 ? -19.743 -8.814 -24.329 1.00 16.20 ? 363 ILE A N 1 ATOM 2878 C CA . ILE A 1 363 ? -18.707 -9.232 -23.375 1.00 17.55 ? 363 ILE A CA 1 ATOM 2879 C C . ILE A 1 363 ? -18.359 -8.124 -22.379 1.00 15.98 ? 363 ILE A C 1 ATOM 2880 O O . ILE A 1 363 ? -18.295 -6.972 -22.741 1.00 16.29 ? 363 ILE A O 1 ATOM 2881 C CB . ILE A 1 363 ? -17.380 -9.684 -24.093 1.00 17.39 ? 363 ILE A CB 1 ATOM 2882 C CG1 . ILE A 1 363 ? -16.817 -8.588 -25.006 1.00 18.76 ? 363 ILE A CG1 1 ATOM 2883 C CG2 . ILE A 1 363 ? -17.642 -10.974 -24.861 1.00 19.46 ? 363 ILE A CG2 1 ATOM 2884 C CD1 . ILE A 1 363 ? -15.288 -8.765 -25.364 1.00 19.11 ? 363 ILE A CD1 1 ATOM 2885 N N . ILE A 1 364 ? -18.093 -8.505 -21.138 1.00 16.07 ? 364 ILE A N 1 ATOM 2886 C CA . ILE A 1 364 ? -17.708 -7.564 -20.119 1.00 16.17 ? 364 ILE A CA 1 ATOM 2887 C C . ILE A 1 364 ? -16.217 -7.365 -20.347 1.00 17.92 ? 364 ILE A C 1 ATOM 2888 O O . ILE A 1 364 ? -15.531 -8.328 -20.688 1.00 16.78 ? 364 ILE A O 1 ATOM 2889 C CB . ILE A 1 364 ? -17.995 -8.090 -18.679 1.00 15.68 ? 364 ILE A CB 1 ATOM 2890 C CG1 . ILE A 1 364 ? -17.983 -6.927 -17.672 1.00 16.47 ? 364 ILE A CG1 1 ATOM 2891 C CG2 . ILE A 1 364 ? -17.010 -9.228 -18.238 1.00 17.99 ? 364 ILE A CG2 1 ATOM 2892 C CD1 . ILE A 1 364 ? -18.524 -7.264 -16.265 1.00 17.05 ? 364 ILE A CD1 1 ATOM 2893 N N . VAL A 1 365 ? -15.768 -6.134 -20.166 1.00 18.46 ? 365 VAL A N 1 ATOM 2894 C CA . VAL A 1 365 ? -14.367 -5.774 -20.222 1.00 21.22 ? 365 VAL A CA 1 ATOM 2895 C C . VAL A 1 365 ? -14.168 -4.841 -19.007 1.00 21.42 ? 365 VAL A C 1 ATOM 2896 O O . VAL A 1 365 ? -15.022 -4.001 -18.704 1.00 21.58 ? 365 VAL A O 1 ATOM 2897 C CB . VAL A 1 365 ? -13.996 -5.089 -21.585 1.00 21.63 ? 365 VAL A CB 1 ATOM 2898 C CG1 . VAL A 1 365 ? -12.516 -4.898 -21.687 1.00 24.10 ? 365 VAL A CG1 1 ATOM 2899 C CG2 . VAL A 1 365 ? -14.426 -5.941 -22.761 1.00 23.25 ? 365 VAL A CG2 1 ATOM 2900 N N . ASP A 1 366 ? -13.051 -5.018 -18.286 1.00 21.30 ? 366 ASP A N 1 ATOM 2901 C CA . ASP A 1 366 ? -12.787 -4.236 -17.089 1.00 20.99 ? 366 ASP A CA 1 ATOM 2902 C C . ASP A 1 366 ? -11.642 -3.282 -17.451 1.00 21.15 ? 366 ASP A C 1 ATOM 2903 O O . ASP A 1 366 ? -10.904 -3.564 -18.387 1.00 19.41 ? 366 ASP A O 1 ATOM 2904 C CB . ASP A 1 366 ? -12.423 -5.159 -15.896 1.00 21.01 ? 366 ASP A CB 1 ATOM 2905 C CG . ASP A 1 366 ? -13.617 -6.016 -15.399 1.00 26.49 ? 366 ASP A CG 1 ATOM 2906 O OD1 . ASP A 1 366 ? -14.733 -5.478 -15.200 1.00 25.40 ? 366 ASP A OD1 1 ATOM 2907 O OD2 . ASP A 1 366 ? -13.420 -7.231 -15.171 1.00 28.91 ? 366 ASP A OD2 1 ATOM 2908 N N . PRO A 1 367 ? -11.563 -2.111 -16.800 1.00 20.38 ? 367 PRO A N 1 ATOM 2909 C CA . PRO A 1 367 ? -10.467 -1.259 -17.159 1.00 21.39 ? 367 PRO A CA 1 ATOM 2910 C C . PRO A 1 367 ? -9.154 -1.847 -16.637 1.00 21.98 ? 367 PRO A C 1 ATOM 2911 O O . PRO A 1 367 ? -8.131 -1.749 -17.326 1.00 23.32 ? 367 PRO A O 1 ATOM 2912 C CB . PRO A 1 367 ? -10.799 0.068 -16.452 1.00 20.90 ? 367 PRO A CB 1 ATOM 2913 C CG . PRO A 1 367 ? -11.699 -0.304 -15.339 1.00 21.81 ? 367 PRO A CG 1 ATOM 2914 C CD . PRO A 1 367 ? -12.466 -1.490 -15.815 1.00 21.17 ? 367 PRO A CD 1 ATOM 2915 N N . ALA A 1 368 ? -9.159 -2.463 -15.453 1.00 21.90 ? 368 ALA A N 1 ATOM 2916 C CA . ALA A 1 368 ? -7.836 -2.762 -14.849 1.00 22.07 ? 368 ALA A CA 1 ATOM 2917 C C . ALA A 1 368 ? -7.214 -3.923 -15.578 1.00 21.96 ? 368 ALA A C 1 ATOM 2918 O O . ALA A 1 368 ? -7.912 -4.856 -15.968 1.00 22.80 ? 368 ALA A O 1 ATOM 2919 C CB . ALA A 1 368 ? -7.962 -3.060 -13.405 1.00 22.79 ? 368 ALA A CB 1 ATOM 2920 N N . ILE A 1 369 ? -5.901 -3.855 -15.749 1.00 20.87 ? 369 ILE A N 1 ATOM 2921 C CA . ILE A 1 369 ? -5.132 -4.785 -16.562 1.00 21.20 ? 369 ILE A CA 1 ATOM 2922 C C . ILE A 1 369 ? -4.111 -5.441 -15.636 1.00 21.05 ? 369 ILE A C 1 ATOM 2923 O O . ILE A 1 369 ? -3.337 -4.739 -14.979 1.00 20.88 ? 369 ILE A O 1 ATOM 2924 C CB . ILE A 1 369 ? -4.366 -4.053 -17.711 1.00 20.44 ? 369 ILE A CB 1 ATOM 2925 C CG1 . ILE A 1 369 ? -5.344 -3.399 -18.705 1.00 20.83 ? 369 ILE A CG1 1 ATOM 2926 C CG2 . ILE A 1 369 ? -3.407 -5.007 -18.455 1.00 22.58 ? 369 ILE A CG2 1 ATOM 2927 C CD1 . ILE A 1 369 ? -6.420 -4.347 -19.267 1.00 19.45 ? 369 ILE A CD1 1 ATOM 2928 N N . SER A 1 370 ? -4.128 -6.769 -15.600 1.00 21.53 ? 370 SER A N 1 ATOM 2929 C CA . SER A 1 370 ? -3.184 -7.555 -14.815 1.00 23.64 ? 370 SER A CA 1 ATOM 2930 C C . SER A 1 370 ? -1.749 -7.136 -15.138 1.00 23.69 ? 370 SER A C 1 ATOM 2931 O O . SER A 1 370 ? -1.418 -7.029 -16.302 1.00 24.14 ? 370 SER A O 1 ATOM 2932 C CB . SER A 1 370 ? -3.322 -9.021 -15.196 1.00 23.22 ? 370 SER A CB 1 ATOM 2933 O OG . SER A 1 370 ? -2.352 -9.784 -14.504 1.00 25.21 ? 370 SER A OG 1 ATOM 2934 N N . ASN A 1 371 ? -0.912 -6.916 -14.130 1.00 24.65 ? 371 ASN A N 1 ATOM 2935 C CA . ASN A 1 371 ? 0.487 -6.540 -14.414 1.00 25.86 ? 371 ASN A CA 1 ATOM 2936 C C . ASN A 1 371 ? 1.433 -7.741 -14.336 1.00 27.63 ? 371 ASN A C 1 ATOM 2937 O O . ASN A 1 371 ? 2.645 -7.587 -14.233 1.00 27.16 ? 371 ASN A O 1 ATOM 2938 C CB . ASN A 1 371 ? 0.994 -5.396 -13.504 1.00 25.00 ? 371 ASN A CB 1 ATOM 2939 C CG . ASN A 1 371 ? 1.110 -5.799 -12.039 1.00 25.87 ? 371 ASN A CG 1 ATOM 2940 O OD1 . ASN A 1 371 ? 0.647 -6.865 -11.629 1.00 25.70 ? 371 ASN A OD1 1 ATOM 2941 N ND2 . ASN A 1 371 ? 1.719 -4.924 -11.233 1.00 27.35 ? 371 ASN A ND2 1 ATOM 2942 N N . ASN A 1 372 ? 0.873 -8.930 -14.383 1.00 28.39 ? 372 ASN A N 1 ATOM 2943 C CA . ASN A 1 372 ? 1.657 -10.141 -14.230 1.00 30.76 ? 372 ASN A CA 1 ATOM 2944 C C . ASN A 1 372 ? 2.022 -10.656 -15.614 1.00 31.39 ? 372 ASN A C 1 ATOM 2945 O O . ASN A 1 372 ? 1.201 -11.248 -16.292 1.00 31.84 ? 372 ASN A O 1 ATOM 2946 C CB . ASN A 1 372 ? 0.859 -11.172 -13.429 1.00 31.21 ? 372 ASN A CB 1 ATOM 2947 C CG . ASN A 1 372 ? 1.725 -12.307 -12.908 1.00 33.86 ? 372 ASN A CG 1 ATOM 2948 O OD1 . ASN A 1 372 ? 2.722 -12.661 -13.516 1.00 34.07 ? 372 ASN A OD1 1 ATOM 2949 N ND2 . ASN A 1 372 ? 1.327 -12.891 -11.790 1.00 37.00 ? 372 ASN A ND2 1 ATOM 2950 N N . SER A 1 373 ? 3.257 -10.406 -16.037 1.00 33.17 ? 373 SER A N 1 ATOM 2951 C CA . SER A 1 373 ? 3.711 -10.822 -17.348 1.00 34.30 ? 373 SER A CA 1 ATOM 2952 C C . SER A 1 373 ? 5.208 -11.076 -17.286 1.00 36.38 ? 373 SER A C 1 ATOM 2953 O O . SER A 1 373 ? 5.928 -10.308 -16.684 1.00 36.89 ? 373 SER A O 1 ATOM 2954 C CB . SER A 1 373 ? 3.435 -9.726 -18.366 1.00 34.34 ? 373 SER A CB 1 ATOM 2955 O OG . SER A 1 373 ? 3.731 -10.141 -19.687 1.00 32.46 ? 373 SER A OG 1 ATOM 2956 N N . SER A 1 374 ? 5.648 -12.165 -17.905 1.00 38.26 ? 374 SER A N 1 ATOM 2957 C CA . SER A 1 374 ? 7.065 -12.552 -17.953 1.00 40.99 ? 374 SER A CA 1 ATOM 2958 C C . SER A 1 374 ? 7.382 -12.970 -19.384 1.00 42.16 ? 374 SER A C 1 ATOM 2959 O O . SER A 1 374 ? 6.455 -13.191 -20.166 1.00 42.58 ? 374 SER A O 1 ATOM 2960 C CB . SER A 1 374 ? 7.324 -13.725 -16.986 1.00 40.53 ? 374 SER A CB 1 ATOM 2961 O OG . SER A 1 374 ? 6.360 -14.774 -17.149 1.00 41.19 ? 374 SER A OG 1 ATOM 2962 N N . SER A 1 375 ? 8.668 -13.080 -19.739 1.00 43.84 ? 375 SER A N 1 ATOM 2963 C CA . SER A 1 375 ? 9.058 -13.734 -21.006 1.00 45.06 ? 375 SER A CA 1 ATOM 2964 C C . SER A 1 375 ? 8.446 -15.145 -21.100 1.00 45.32 ? 375 SER A C 1 ATOM 2965 O O . SER A 1 375 ? 7.905 -15.553 -22.140 1.00 46.13 ? 375 SER A O 1 ATOM 2966 C CB . SER A 1 375 ? 10.584 -13.825 -21.124 1.00 45.84 ? 375 SER A CB 1 ATOM 2967 O OG . SER A 1 375 ? 11.195 -12.556 -20.920 1.00 47.64 ? 375 SER A OG 1 ATOM 2968 N N . SER A 1 376 ? 8.512 -15.865 -19.987 1.00 45.30 ? 376 SER A N 1 ATOM 2969 C CA . SER A 1 376 ? 7.973 -17.208 -19.870 1.00 45.47 ? 376 SER A CA 1 ATOM 2970 C C . SER A 1 376 ? 6.473 -17.257 -20.205 1.00 44.82 ? 376 SER A C 1 ATOM 2971 O O . SER A 1 376 ? 6.024 -18.109 -20.976 1.00 45.06 ? 376 SER A O 1 ATOM 2972 C CB . SER A 1 376 ? 8.222 -17.718 -18.442 1.00 45.69 ? 376 SER A CB 1 ATOM 2973 O OG . SER A 1 376 ? 7.848 -19.076 -18.284 1.00 47.45 ? 376 SER A OG 1 ATOM 2974 N N . LYS A 1 377 ? 5.702 -16.344 -19.614 1.00 43.48 ? 377 LYS A N 1 ATOM 2975 C CA . LYS A 1 377 ? 4.255 -16.294 -19.842 1.00 42.07 ? 377 LYS A CA 1 ATOM 2976 C C . LYS A 1 377 ? 3.801 -14.825 -20.065 1.00 39.39 ? 377 LYS A C 1 ATOM 2977 O O . LYS A 1 377 ? 3.407 -14.132 -19.115 1.00 38.44 ? 377 LYS A O 1 ATOM 2978 C CB . LYS A 1 377 ? 3.540 -16.938 -18.654 1.00 42.88 ? 377 LYS A CB 1 ATOM 2979 C CG . LYS A 1 377 ? 2.384 -17.867 -19.040 1.00 46.88 ? 377 LYS A CG 1 ATOM 2980 C CD . LYS A 1 377 ? 2.812 -19.341 -19.057 1.00 50.78 ? 377 LYS A CD 1 ATOM 2981 C CE . LYS A 1 377 ? 1.701 -20.223 -19.639 1.00 51.72 ? 377 LYS A CE 1 ATOM 2982 N NZ . LYS A 1 377 ? 1.908 -21.668 -19.335 1.00 52.68 ? 377 LYS A NZ 1 ATOM 2983 N N . PRO A 1 378 ? 3.948 -14.318 -21.304 1.00 37.54 ? 378 PRO A N 1 ATOM 2984 C CA . PRO A 1 378 ? 3.586 -12.913 -21.550 1.00 35.66 ? 378 PRO A CA 1 ATOM 2985 C C . PRO A 1 378 ? 2.078 -12.643 -21.443 1.00 33.37 ? 378 PRO A C 1 ATOM 2986 O O . PRO A 1 378 ? 1.284 -13.485 -21.824 1.00 33.60 ? 378 PRO A O 1 ATOM 2987 C CB . PRO A 1 378 ? 4.076 -12.652 -22.982 1.00 35.97 ? 378 PRO A CB 1 ATOM 2988 C CG . PRO A 1 378 ? 4.260 -13.991 -23.601 1.00 36.78 ? 378 PRO A CG 1 ATOM 2989 C CD . PRO A 1 378 ? 4.516 -14.971 -22.502 1.00 37.34 ? 378 PRO A CD 1 ATOM 2990 N N . TYR A 1 379 ? 1.701 -11.487 -20.902 1.00 30.67 ? 379 TYR A N 1 ATOM 2991 C CA . TYR A 1 379 ? 0.308 -11.055 -20.982 1.00 27.85 ? 379 TYR A CA 1 ATOM 2992 C C . TYR A 1 379 ? 0.324 -9.856 -21.896 1.00 26.13 ? 379 TYR A C 1 ATOM 2993 O O . TYR A 1 379 ? 0.689 -8.750 -21.489 1.00 25.86 ? 379 TYR A O 1 ATOM 2994 C CB . TYR A 1 379 ? -0.290 -10.743 -19.592 1.00 26.21 ? 379 TYR A CB 1 ATOM 2995 C CG . TYR A 1 379 ? -1.745 -10.287 -19.634 1.00 24.32 ? 379 TYR A CG 1 ATOM 2996 C CD1 . TYR A 1 379 ? -2.734 -11.052 -20.289 1.00 21.21 ? 379 TYR A CD1 1 ATOM 2997 C CD2 . TYR A 1 379 ? -2.135 -9.104 -19.007 1.00 24.07 ? 379 TYR A CD2 1 ATOM 2998 C CE1 . TYR A 1 379 ? -4.104 -10.607 -20.323 1.00 23.02 ? 379 TYR A CE1 1 ATOM 2999 C CE2 . TYR A 1 379 ? -3.473 -8.668 -19.029 1.00 22.88 ? 379 TYR A CE2 1 ATOM 3000 C CZ . TYR A 1 379 ? -4.441 -9.418 -19.683 1.00 23.21 ? 379 TYR A CZ 1 ATOM 3001 O OH . TYR A 1 379 ? -5.754 -8.951 -19.688 1.00 23.21 ? 379 TYR A OH 1 ATOM 3002 N N . GLY A 1 380 ? -0.025 -10.115 -23.155 1.00 25.11 ? 380 GLY A N 1 ATOM 3003 C CA . GLY A 1 380 ? -0.002 -9.134 -24.241 1.00 23.97 ? 380 GLY A CA 1 ATOM 3004 C C . GLY A 1 380 ? -0.568 -7.765 -23.938 1.00 23.11 ? 380 GLY A C 1 ATOM 3005 O O . GLY A 1 380 ? 0.081 -6.785 -24.204 1.00 22.10 ? 380 GLY A O 1 ATOM 3006 N N . PRO A 1 381 ? -1.821 -7.682 -23.405 1.00 22.79 ? 381 PRO A N 1 ATOM 3007 C CA . PRO A 1 381 ? -2.435 -6.359 -23.081 1.00 22.32 ? 381 PRO A CA 1 ATOM 3008 C C . PRO A 1 381 ? -1.601 -5.469 -22.155 1.00 22.28 ? 381 PRO A C 1 ATOM 3009 O O . PRO A 1 381 ? -1.492 -4.265 -22.382 1.00 22.50 ? 381 PRO A O 1 ATOM 3010 C CB . PRO A 1 381 ? -3.790 -6.750 -22.439 1.00 21.78 ? 381 PRO A CB 1 ATOM 3011 C CG . PRO A 1 381 ? -4.102 -8.050 -23.092 1.00 21.79 ? 381 PRO A CG 1 ATOM 3012 C CD . PRO A 1 381 ? -2.768 -8.786 -23.170 1.00 22.64 ? 381 PRO A CD 1 ATOM 3013 N N . TYR A 1 382 ? -0.977 -6.067 -21.151 1.00 23.33 ? 382 TYR A N 1 ATOM 3014 C CA . TYR A 1 382 ? -0.093 -5.335 -20.254 1.00 23.87 ? 382 TYR A CA 1 ATOM 3015 C C . TYR A 1 382 ? 1.202 -4.939 -20.948 1.00 24.20 ? 382 TYR A C 1 ATOM 3016 O O . TYR A 1 382 ? 1.670 -3.803 -20.795 1.00 23.65 ? 382 TYR A O 1 ATOM 3017 C CB . TYR A 1 382 ? 0.224 -6.165 -19.007 1.00 24.53 ? 382 TYR A CB 1 ATOM 3018 C CG . TYR A 1 382 ? 1.249 -5.515 -18.119 1.00 25.08 ? 382 TYR A CG 1 ATOM 3019 C CD1 . TYR A 1 382 ? 0.913 -4.396 -17.366 1.00 24.83 ? 382 TYR A CD1 1 ATOM 3020 C CD2 . TYR A 1 382 ? 2.566 -6.001 -18.043 1.00 27.32 ? 382 TYR A CD2 1 ATOM 3021 C CE1 . TYR A 1 382 ? 1.833 -3.772 -16.547 1.00 26.84 ? 382 TYR A CE1 1 ATOM 3022 C CE2 . TYR A 1 382 ? 3.514 -5.377 -17.219 1.00 27.24 ? 382 TYR A CE2 1 ATOM 3023 C CZ . TYR A 1 382 ? 3.128 -4.259 -16.467 1.00 27.65 ? 382 TYR A CZ 1 ATOM 3024 O OH . TYR A 1 382 ? 4.027 -3.593 -15.640 1.00 28.46 ? 382 TYR A OH 1 ATOM 3025 N N . ASP A 1 383 ? 1.808 -5.871 -21.686 1.00 24.53 ? 383 ASP A N 1 ATOM 3026 C CA . ASP A 1 383 ? 3.059 -5.541 -22.396 1.00 26.06 ? 383 ASP A CA 1 ATOM 3027 C C . ASP A 1 383 ? 2.874 -4.395 -23.381 1.00 25.92 ? 383 ASP A C 1 ATOM 3028 O O . ASP A 1 383 ? 3.690 -3.476 -23.412 1.00 25.51 ? 383 ASP A O 1 ATOM 3029 C CB . ASP A 1 383 ? 3.609 -6.763 -23.149 1.00 26.69 ? 383 ASP A CB 1 ATOM 3030 C CG . ASP A 1 383 ? 3.974 -7.920 -22.232 1.00 29.92 ? 383 ASP A CG 1 ATOM 3031 O OD1 . ASP A 1 383 ? 4.034 -7.759 -20.988 1.00 31.15 ? 383 ASP A OD1 1 ATOM 3032 O OD2 . ASP A 1 383 ? 4.209 -9.023 -22.784 1.00 35.00 ? 383 ASP A OD2 1 ATOM 3033 N N . ARG A 1 384 ? 1.805 -4.471 -24.192 1.00 24.68 ? 384 ARG A N 1 ATOM 3034 C CA . ARG A 1 384 ? 1.528 -3.471 -25.217 1.00 24.94 ? 384 ARG A CA 1 ATOM 3035 C C . ARG A 1 384 ? 1.181 -2.144 -24.574 1.00 24.39 ? 384 ARG A C 1 ATOM 3036 O O . ARG A 1 384 ? 1.645 -1.100 -25.031 1.00 24.61 ? 384 ARG A O 1 ATOM 3037 C CB . ARG A 1 384 ? 0.392 -3.927 -26.156 1.00 24.36 ? 384 ARG A CB 1 ATOM 3038 C CG . ARG A 1 384 ? 0.756 -5.046 -27.146 1.00 24.90 ? 384 ARG A CG 1 ATOM 3039 C CD . ARG A 1 384 ? -0.388 -5.417 -28.097 1.00 26.33 ? 384 ARG A CD 1 ATOM 3040 N NE . ARG A 1 384 ? -1.450 -6.167 -27.430 1.00 26.45 ? 384 ARG A NE 1 ATOM 3041 C CZ . ARG A 1 384 ? -1.487 -7.492 -27.351 1.00 26.63 ? 384 ARG A CZ 1 ATOM 3042 N NH1 . ARG A 1 384 ? -0.522 -8.210 -27.899 1.00 28.37 ? 384 ARG A NH1 1 ATOM 3043 N NH2 . ARG A 1 384 ? -2.480 -8.104 -26.724 1.00 25.71 ? 384 ARG A NH2 1 ATOM 3044 N N . GLY A 1 385 ? 0.389 -2.186 -23.494 1.00 24.02 ? 385 GLY A N 1 ATOM 3045 C CA . GLY A 1 385 ? 0.069 -0.982 -22.708 1.00 23.57 ? 385 GLY A CA 1 ATOM 3046 C C . GLY A 1 385 ? 1.288 -0.327 -22.060 1.00 24.59 ? 385 GLY A C 1 ATOM 3047 O O . GLY A 1 385 ? 1.415 0.888 -22.064 1.00 22.99 ? 385 GLY A O 1 ATOM 3048 N N . SER A 1 386 ? 2.198 -1.133 -21.516 1.00 25.49 ? 386 SER A N 1 ATOM 3049 C CA . SER A 1 386 ? 3.449 -0.586 -20.934 1.00 27.62 ? 386 SER A CA 1 ATOM 3050 C C . SER A 1 386 ? 4.369 0.007 -21.992 1.00 27.98 ? 386 SER A C 1 ATOM 3051 O O . SER A 1 386 ? 4.966 1.039 -21.777 1.00 28.75 ? 386 SER A O 1 ATOM 3052 C CB . SER A 1 386 ? 4.210 -1.659 -20.167 1.00 26.99 ? 386 SER A CB 1 ATOM 3053 O OG . SER A 1 386 ? 3.347 -2.236 -19.236 1.00 27.71 ? 386 SER A OG 1 ATOM 3054 N N . ASP A 1 387 ? 4.458 -0.658 -23.136 1.00 30.17 ? 387 ASP A N 1 ATOM 3055 C CA . ASP A 1 387 ? 5.202 -0.142 -24.286 1.00 30.98 ? 387 ASP A CA 1 ATOM 3056 C C . ASP A 1 387 ? 4.690 1.222 -24.722 1.00 31.23 ? 387 ASP A C 1 ATOM 3057 O O . ASP A 1 387 ? 5.476 2.096 -25.092 1.00 29.99 ? 387 ASP A O 1 ATOM 3058 C CB . ASP A 1 387 ? 5.111 -1.119 -25.449 1.00 31.97 ? 387 ASP A CB 1 ATOM 3059 C CG . ASP A 1 387 ? 6.006 -2.350 -25.260 1.00 36.03 ? 387 ASP A CG 1 ATOM 3060 O OD1 . ASP A 1 387 ? 6.809 -2.417 -24.284 1.00 38.00 ? 387 ASP A OD1 1 ATOM 3061 O OD2 . ASP A 1 387 ? 5.895 -3.258 -26.106 1.00 40.11 ? 387 ASP A OD2 1 ATOM 3062 N N . MET A 1 388 ? 3.367 1.414 -24.672 1.00 30.01 ? 388 MET A N 1 ATOM 3063 C CA . MET A 1 388 ? 2.780 2.694 -25.062 1.00 31.35 ? 388 MET A CA 1 ATOM 3064 C C . MET A 1 388 ? 2.705 3.738 -23.944 1.00 29.13 ? 388 MET A C 1 ATOM 3065 O O . MET A 1 388 ? 2.400 4.901 -24.192 1.00 29.35 ? 388 MET A O 1 ATOM 3066 C CB . MET A 1 388 ? 1.410 2.488 -25.712 1.00 30.42 ? 388 MET A CB 1 ATOM 3067 C CG . MET A 1 388 ? 1.490 1.703 -27.023 1.00 34.31 ? 388 MET A CG 1 ATOM 3068 S SD . MET A 1 388 ? -0.149 1.464 -27.719 1.00 37.12 ? 388 MET A SD 1 ATOM 3069 C CE . MET A 1 388 ? -0.504 3.155 -28.206 1.00 34.81 ? 388 MET A CE 1 ATOM 3070 N N . LYS A 1 389 ? 2.991 3.310 -22.723 1.00 27.76 ? 389 LYS A N 1 ATOM 3071 C CA . LYS A 1 389 ? 3.093 4.190 -21.558 1.00 27.10 ? 389 LYS A CA 1 ATOM 3072 C C . LYS A 1 389 ? 1.762 4.915 -21.243 1.00 24.93 ? 389 LYS A C 1 ATOM 3073 O O . LYS A 1 389 ? 1.759 6.100 -20.911 1.00 24.29 ? 389 LYS A O 1 ATOM 3074 C CB . LYS A 1 389 ? 4.288 5.169 -21.685 1.00 26.69 ? 389 LYS A CB 1 ATOM 3075 C CG . LYS A 1 389 ? 5.641 4.446 -21.801 1.00 28.47 ? 389 LYS A CG 1 ATOM 3076 C CD . LYS A 1 389 ? 6.782 5.427 -21.984 1.00 30.95 ? 389 LYS A CD 1 ATOM 3077 C CE . LYS A 1 389 ? 8.129 4.683 -22.131 1.00 37.02 ? 389 LYS A CE 1 ATOM 3078 N NZ . LYS A 1 389 ? 8.435 3.823 -20.912 1.00 40.29 ? 389 LYS A NZ 1 ATOM 3079 N N . ILE A 1 390 ? 0.671 4.152 -21.299 1.00 23.90 ? 390 ILE A N 1 ATOM 3080 C CA . ILE A 1 390 ? -0.691 4.695 -21.207 1.00 22.31 ? 390 ILE A CA 1 ATOM 3081 C C . ILE A 1 390 ? -1.385 4.417 -19.866 1.00 22.39 ? 390 ILE A C 1 ATOM 3082 O O . ILE A 1 390 ? -2.619 4.538 -19.757 1.00 20.42 ? 390 ILE A O 1 ATOM 3083 C CB . ILE A 1 390 ? -1.597 4.219 -22.403 1.00 23.64 ? 390 ILE A CB 1 ATOM 3084 C CG1 . ILE A 1 390 ? -1.494 2.718 -22.693 1.00 24.14 ? 390 ILE A CG1 1 ATOM 3085 C CG2 . ILE A 1 390 ? -1.260 5.012 -23.673 1.00 23.72 ? 390 ILE A CG2 1 ATOM 3086 C CD1 . ILE A 1 390 ? -2.182 1.756 -21.693 1.00 24.96 ? 390 ILE A CD1 1 ATOM 3087 N N . TRP A 1 391 ? -0.613 4.041 -18.838 1.00 20.71 ? 391 TRP A N 1 ATOM 3088 C CA . TRP A 1 391 ? -1.223 3.800 -17.515 1.00 21.13 ? 391 TRP A CA 1 ATOM 3089 C C . TRP A 1 391 ? -1.417 5.069 -16.712 1.00 20.10 ? 391 TRP A C 1 ATOM 3090 O O . TRP A 1 391 ? -0.750 6.069 -16.954 1.00 21.02 ? 391 TRP A O 1 ATOM 3091 C CB . TRP A 1 391 ? -0.445 2.772 -16.680 1.00 21.50 ? 391 TRP A CB 1 ATOM 3092 C CG . TRP A 1 391 ? 0.007 1.544 -17.414 1.00 21.08 ? 391 TRP A CG 1 ATOM 3093 C CD1 . TRP A 1 391 ? 1.312 1.114 -17.578 1.00 23.12 ? 391 TRP A CD1 1 ATOM 3094 C CD2 . TRP A 1 391 ? -0.810 0.586 -18.071 1.00 22.58 ? 391 TRP A CD2 1 ATOM 3095 N NE1 . TRP A 1 391 ? 1.335 -0.062 -18.289 1.00 23.28 ? 391 TRP A NE1 1 ATOM 3096 C CE2 . TRP A 1 391 ? 0.046 -0.403 -18.607 1.00 21.33 ? 391 TRP A CE2 1 ATOM 3097 C CE3 . TRP A 1 391 ? -2.191 0.456 -18.258 1.00 17.66 ? 391 TRP A CE3 1 ATOM 3098 C CZ2 . TRP A 1 391 ? -0.437 -1.499 -19.320 1.00 23.26 ? 391 TRP A CZ2 1 ATOM 3099 C CZ3 . TRP A 1 391 ? -2.664 -0.627 -18.969 1.00 23.14 ? 391 TRP A CZ3 1 ATOM 3100 C CH2 . TRP A 1 391 ? -1.795 -1.593 -19.490 1.00 21.91 ? 391 TRP A CH2 1 ATOM 3101 N N . VAL A 1 392 ? -2.339 5.020 -15.751 1.00 19.79 ? 392 VAL A N 1 ATOM 3102 C CA . VAL A 1 392 ? -2.444 6.026 -14.717 1.00 18.91 ? 392 VAL A CA 1 ATOM 3103 C C . VAL A 1 392 ? -1.192 5.890 -13.841 1.00 20.67 ? 392 VAL A C 1 ATOM 3104 O O . VAL A 1 392 ? -0.848 4.773 -13.433 1.00 20.96 ? 392 VAL A O 1 ATOM 3105 C CB . VAL A 1 392 ? -3.671 5.778 -13.822 1.00 18.04 ? 392 VAL A CB 1 ATOM 3106 C CG1 . VAL A 1 392 ? -3.687 6.778 -12.661 1.00 17.43 ? 392 VAL A CG1 1 ATOM 3107 C CG2 . VAL A 1 392 ? -4.955 5.842 -14.657 1.00 16.12 ? 392 VAL A CG2 1 ATOM 3108 N N . ASN A 1 393 ? -0.528 7.016 -13.596 1.00 21.52 ? 393 ASN A N 1 ATOM 3109 C CA . ASN A 1 393 ? 0.682 7.064 -12.785 1.00 23.06 ? 393 ASN A CA 1 ATOM 3110 C C . ASN A 1 393 ? 0.403 7.488 -11.374 1.00 23.91 ? 393 ASN A C 1 ATOM 3111 O O . ASN A 1 393 ? -0.610 8.126 -11.077 1.00 21.73 ? 393 ASN A O 1 ATOM 3112 C CB . ASN A 1 393 ? 1.699 8.039 -13.395 1.00 22.91 ? 393 ASN A CB 1 ATOM 3113 C CG . ASN A 1 393 ? 2.191 7.581 -14.744 1.00 22.07 ? 393 ASN A CG 1 ATOM 3114 O OD1 . ASN A 1 393 ? 2.132 6.395 -15.063 1.00 22.78 ? 393 ASN A OD1 1 ATOM 3115 N ND2 . ASN A 1 393 ? 2.655 8.521 -15.545 1.00 23.36 ? 393 ASN A ND2 1 ATOM 3116 N N . SER A 1 394 ? 1.335 7.115 -10.505 1.00 25.93 ? 394 SER A N 1 ATOM 3117 C CA . SER A 1 394 ? 1.380 7.613 -9.152 1.00 27.91 ? 394 SER A CA 1 ATOM 3118 C C . SER A 1 394 ? 1.765 9.079 -9.140 1.00 28.33 ? 394 SER A C 1 ATOM 3119 O O . SER A 1 394 ? 2.125 9.651 -10.161 1.00 28.55 ? 394 SER A O 1 ATOM 3120 C CB . SER A 1 394 ? 2.389 6.795 -8.338 1.00 28.84 ? 394 SER A CB 1 ATOM 3121 O OG . SER A 1 394 ? 2.002 5.444 -8.320 1.00 34.02 ? 394 SER A OG 1 ATOM 3122 N N . SER A 1 395 ? 1.701 9.699 -7.971 1.00 29.11 ? 395 SER A N 1 ATOM 3123 C CA . SER A 1 395 ? 1.996 11.114 -7.859 1.00 30.46 ? 395 SER A CA 1 ATOM 3124 C C . SER A 1 395 ? 3.405 11.518 -8.333 1.00 30.93 ? 395 SER A C 1 ATOM 3125 O O . SER A 1 395 ? 3.617 12.677 -8.650 1.00 31.98 ? 395 SER A O 1 ATOM 3126 C CB . SER A 1 395 ? 1.738 11.604 -6.432 1.00 30.41 ? 395 SER A CB 1 ATOM 3127 O OG . SER A 1 395 ? 2.550 10.894 -5.514 1.00 31.72 ? 395 SER A OG 1 ATOM 3128 N N . ASP A 1 396 ? 4.353 10.589 -8.411 1.00 31.37 ? 396 ASP A N 1 ATOM 3129 C CA . ASP A 1 396 ? 5.677 10.941 -8.982 1.00 31.95 ? 396 ASP A CA 1 ATOM 3130 C C . ASP A 1 396 ? 5.585 11.286 -10.471 1.00 31.70 ? 396 ASP A C 1 ATOM 3131 O O . ASP A 1 396 ? 6.526 11.821 -11.063 1.00 31.52 ? 396 ASP A O 1 ATOM 3132 C CB . ASP A 1 396 ? 6.743 9.870 -8.707 1.00 32.48 ? 396 ASP A CB 1 ATOM 3133 C CG . ASP A 1 396 ? 6.455 8.538 -9.398 1.00 34.35 ? 396 ASP A CG 1 ATOM 3134 O OD1 . ASP A 1 396 ? 5.574 8.475 -10.291 1.00 35.43 ? 396 ASP A OD1 1 ATOM 3135 O OD2 . ASP A 1 396 ? 7.142 7.548 -9.055 1.00 36.12 ? 396 ASP A OD2 1 ATOM 3136 N N . GLY A 1 397 ? 4.430 10.991 -11.071 1.00 30.85 ? 397 GLY A N 1 ATOM 3137 C CA . GLY A 1 397 ? 4.191 11.321 -12.463 1.00 29.81 ? 397 GLY A CA 1 ATOM 3138 C C . GLY A 1 397 ? 4.806 10.345 -13.456 1.00 29.77 ? 397 GLY A C 1 ATOM 3139 O O . GLY A 1 397 ? 4.629 10.531 -14.658 1.00 29.83 ? 397 GLY A O 1 ATOM 3140 N N . VAL A 1 398 ? 5.515 9.309 -12.983 1.00 29.14 ? 398 VAL A N 1 ATOM 3141 C CA . VAL A 1 398 ? 6.239 8.381 -13.904 1.00 29.33 ? 398 VAL A CA 1 ATOM 3142 C C . VAL A 1 398 ? 6.068 6.889 -13.637 1.00 28.43 ? 398 VAL A C 1 ATOM 3143 O O . VAL A 1 398 ? 6.314 6.061 -14.512 1.00 29.24 ? 398 VAL A O 1 ATOM 3144 C CB . VAL A 1 398 ? 7.764 8.695 -14.027 1.00 30.55 ? 398 VAL A CB 1 ATOM 3145 C CG1 . VAL A 1 398 ? 7.999 9.950 -14.862 1.00 31.89 ? 398 VAL A CG1 1 ATOM 3146 C CG2 . VAL A 1 398 ? 8.419 8.784 -12.642 1.00 30.60 ? 398 VAL A CG2 1 ATOM 3147 N N . THR A 1 399 ? 5.624 6.539 -12.439 1.00 27.46 ? 399 THR A N 1 ATOM 3148 C CA . THR A 1 399 ? 5.449 5.158 -12.074 1.00 26.98 ? 399 THR A CA 1 ATOM 3149 C C . THR A 1 399 ? 3.974 4.793 -12.193 1.00 25.96 ? 399 THR A C 1 ATOM 3150 O O . THR A 1 399 ? 3.155 5.388 -11.512 1.00 24.01 ? 399 THR A O 1 ATOM 3151 C CB . THR A 1 399 ? 5.943 4.926 -10.634 1.00 27.80 ? 399 THR A CB 1 ATOM 3152 O OG1 . THR A 1 399 ? 7.299 5.394 -10.545 1.00 29.10 ? 399 THR A OG1 1 ATOM 3153 C CG2 . THR A 1 399 ? 5.890 3.461 -10.256 1.00 28.21 ? 399 THR A CG2 1 ATOM 3154 N N . PRO A 1 400 ? 3.650 3.818 -13.053 1.00 25.68 ? 400 PRO A N 1 ATOM 3155 C CA . PRO A 1 400 ? 2.261 3.371 -13.099 1.00 24.77 ? 400 PRO A CA 1 ATOM 3156 C C . PRO A 1 400 ? 1.729 2.951 -11.725 1.00 25.00 ? 400 PRO A C 1 ATOM 3157 O O . PRO A 1 400 ? 2.385 2.193 -10.967 1.00 23.95 ? 400 PRO A O 1 ATOM 3158 C CB . PRO A 1 400 ? 2.308 2.161 -14.041 1.00 25.57 ? 400 PRO A CB 1 ATOM 3159 C CG . PRO A 1 400 ? 3.452 2.379 -14.893 1.00 26.35 ? 400 PRO A CG 1 ATOM 3160 C CD . PRO A 1 400 ? 4.485 3.111 -14.040 1.00 24.46 ? 400 PRO A CD 1 ATOM 3161 N N . LEU A 1 401 ? 0.529 3.422 -11.405 1.00 23.33 ? 401 LEU A N 1 ATOM 3162 C CA . LEU A 1 401 ? -0.088 3.080 -10.139 1.00 23.81 ? 401 LEU A CA 1 ATOM 3163 C C . LEU A 1 401 ? -0.560 1.620 -10.095 1.00 23.68 ? 401 LEU A C 1 ATOM 3164 O O . LEU A 1 401 ? -1.238 1.151 -11.021 1.00 23.63 ? 401 LEU A O 1 ATOM 3165 C CB . LEU A 1 401 ? -1.254 4.057 -9.864 1.00 22.54 ? 401 LEU A CB 1 ATOM 3166 C CG . LEU A 1 401 ? -2.029 3.883 -8.547 1.00 25.48 ? 401 LEU A CG 1 ATOM 3167 C CD1 . LEU A 1 401 ? -2.613 5.179 -8.101 1.00 24.96 ? 401 LEU A CD1 1 ATOM 3168 C CD2 . LEU A 1 401 ? -3.151 2.825 -8.667 1.00 26.70 ? 401 LEU A CD2 1 ATOM 3169 N N . ILE A 1 402 ? -0.245 0.921 -8.997 1.00 23.09 ? 402 ILE A N 1 ATOM 3170 C CA . ILE A 1 402 ? -0.648 -0.470 -8.841 1.00 22.87 ? 402 ILE A CA 1 ATOM 3171 C C . ILE A 1 402 ? -1.815 -0.600 -7.867 1.00 22.41 ? 402 ILE A C 1 ATOM 3172 O O . ILE A 1 402 ? -1.751 -0.124 -6.734 1.00 22.38 ? 402 ILE A O 1 ATOM 3173 C CB . ILE A 1 402 ? 0.507 -1.392 -8.344 1.00 23.37 ? 402 ILE A CB 1 ATOM 3174 C CG1 . ILE A 1 402 ? 1.811 -1.213 -9.151 1.00 24.59 ? 402 ILE A CG1 1 ATOM 3175 C CG2 . ILE A 1 402 ? 0.069 -2.844 -8.331 1.00 22.33 ? 402 ILE A CG2 1 ATOM 3176 C CD1 . ILE A 1 402 ? 1.661 -1.408 -10.619 1.00 28.51 ? 402 ILE A CD1 1 ATOM 3177 N N . GLY A 1 403 ? -2.891 -1.226 -8.324 1.00 21.76 ? 403 GLY A N 1 ATOM 3178 C CA . GLY A 1 403 ? -4.036 -1.482 -7.455 1.00 20.86 ? 403 GLY A CA 1 ATOM 3179 C C . GLY A 1 403 ? -4.392 -2.948 -7.532 1.00 21.29 ? 403 GLY A C 1 ATOM 3180 O O . GLY A 1 403 ? -3.595 -3.758 -7.963 1.00 21.78 ? 403 GLY A O 1 ATOM 3181 N N . GLU A 1 404 ? -5.599 -3.322 -7.131 1.00 20.93 ? 404 GLU A N 1 ATOM 3182 C CA . GLU A 1 404 ? -5.966 -4.711 -7.189 1.00 22.21 ? 404 GLU A CA 1 ATOM 3183 C C . GLU A 1 404 ? -7.404 -4.830 -7.652 1.00 21.97 ? 404 GLU A C 1 ATOM 3184 O O . GLU A 1 404 ? -8.273 -4.195 -7.083 1.00 22.16 ? 404 GLU A O 1 ATOM 3185 C CB . GLU A 1 404 ? -5.834 -5.325 -5.789 1.00 23.53 ? 404 GLU A CB 1 ATOM 3186 C CG . GLU A 1 404 ? -5.978 -6.822 -5.764 1.00 29.25 ? 404 GLU A CG 1 ATOM 3187 C CD . GLU A 1 404 ? -6.336 -7.339 -4.374 1.00 37.84 ? 404 GLU A CD 1 ATOM 3188 O OE1 . GLU A 1 404 ? -5.811 -6.753 -3.391 1.00 39.54 ? 404 GLU A OE1 1 ATOM 3189 O OE2 . GLU A 1 404 ? -7.145 -8.306 -4.274 1.00 39.01 ? 404 GLU A OE2 1 ATOM 3190 N N . VAL A 1 405 ? -7.651 -5.630 -8.679 1.00 21.48 ? 405 VAL A N 1 ATOM 3191 C CA . VAL A 1 405 ? -9.043 -5.920 -9.079 1.00 21.35 ? 405 VAL A CA 1 ATOM 3192 C C . VAL A 1 405 ? -9.173 -7.421 -9.321 1.00 21.64 ? 405 VAL A C 1 ATOM 3193 O O . VAL A 1 405 ? -8.523 -8.190 -8.630 1.00 22.38 ? 405 VAL A O 1 ATOM 3194 C CB . VAL A 1 405 ? -9.591 -4.973 -10.220 1.00 20.33 ? 405 VAL A CB 1 ATOM 3195 C CG1 . VAL A 1 405 ? -11.136 -4.920 -10.155 1.00 20.19 ? 405 VAL A CG1 1 ATOM 3196 C CG2 . VAL A 1 405 ? -9.076 -3.554 -10.005 1.00 19.40 ? 405 VAL A CG2 1 ATOM 3197 N N . TRP A 1 406 ? -10.039 -7.850 -10.228 1.00 22.02 ? 406 TRP A N 1 ATOM 3198 C CA . TRP A 1 406 ? -10.361 -9.266 -10.419 1.00 22.28 ? 406 TRP A CA 1 ATOM 3199 C C . TRP A 1 406 ? -9.166 -10.191 -10.694 1.00 22.77 ? 406 TRP A C 1 ATOM 3200 O O . TRP A 1 406 ? -9.086 -11.268 -10.109 1.00 23.02 ? 406 TRP A O 1 ATOM 3201 C CB . TRP A 1 406 ? -11.401 -9.418 -11.528 1.00 21.59 ? 406 TRP A CB 1 ATOM 3202 C CG . TRP A 1 406 ? -12.731 -8.762 -11.192 1.00 19.72 ? 406 TRP A CG 1 ATOM 3203 C CD1 . TRP A 1 406 ? -13.357 -7.791 -11.903 1.00 21.32 ? 406 TRP A CD1 1 ATOM 3204 C CD2 . TRP A 1 406 ? -13.580 -9.050 -10.069 1.00 22.83 ? 406 TRP A CD2 1 ATOM 3205 N NE1 . TRP A 1 406 ? -14.566 -7.453 -11.304 1.00 20.31 ? 406 TRP A NE1 1 ATOM 3206 C CE2 . TRP A 1 406 ? -14.729 -8.218 -10.181 1.00 19.06 ? 406 TRP A CE2 1 ATOM 3207 C CE3 . TRP A 1 406 ? -13.500 -9.947 -8.994 1.00 21.56 ? 406 TRP A CE3 1 ATOM 3208 C CZ2 . TRP A 1 406 ? -15.756 -8.223 -9.232 1.00 23.03 ? 406 TRP A CZ2 1 ATOM 3209 C CZ3 . TRP A 1 406 ? -14.522 -9.962 -8.053 1.00 22.96 ? 406 TRP A CZ3 1 ATOM 3210 C CH2 . TRP A 1 406 ? -15.651 -9.107 -8.185 1.00 22.54 ? 406 TRP A CH2 1 ATOM 3211 N N . PRO A 1 407 ? -8.247 -9.790 -11.579 1.00 23.56 ? 407 PRO A N 1 ATOM 3212 C CA . PRO A 1 407 ? -7.138 -10.721 -11.788 1.00 24.65 ? 407 PRO A CA 1 ATOM 3213 C C . PRO A 1 407 ? -5.997 -10.698 -10.725 1.00 26.24 ? 407 PRO A C 1 ATOM 3214 O O . PRO A 1 407 ? -4.982 -11.396 -10.900 1.00 27.48 ? 407 PRO A O 1 ATOM 3215 C CB . PRO A 1 407 ? -6.614 -10.313 -13.169 1.00 24.22 ? 407 PRO A CB 1 ATOM 3216 C CG . PRO A 1 407 ? -6.868 -8.874 -13.263 1.00 22.93 ? 407 PRO A CG 1 ATOM 3217 C CD . PRO A 1 407 ? -8.142 -8.606 -12.453 1.00 24.40 ? 407 PRO A CD 1 ATOM 3218 N N . GLY A 1 408 ? -6.158 -9.933 -9.651 1.00 25.76 ? 408 GLY A N 1 ATOM 3219 C CA . GLY A 1 408 ? -5.031 -9.637 -8.745 1.00 25.25 ? 408 GLY A CA 1 ATOM 3220 C C . GLY A 1 408 ? -4.446 -8.256 -8.991 1.00 24.74 ? 408 GLY A C 1 ATOM 3221 O O . GLY A 1 408 ? -5.167 -7.352 -9.377 1.00 24.47 ? 408 GLY A O 1 ATOM 3222 N N . GLN A 1 409 ? -3.129 -8.070 -8.795 1.00 23.87 ? 409 GLN A N 1 ATOM 3223 C CA . GLN A 1 409 ? -2.529 -6.744 -8.992 1.00 23.56 ? 409 GLN A CA 1 ATOM 3224 C C . GLN A 1 409 ? -2.708 -6.261 -10.402 1.00 22.23 ? 409 GLN A C 1 ATOM 3225 O O . GLN A 1 409 ? -2.581 -7.041 -11.363 1.00 22.35 ? 409 GLN A O 1 ATOM 3226 C CB . GLN A 1 409 ? -1.033 -6.721 -8.682 1.00 23.92 ? 409 GLN A CB 1 ATOM 3227 C CG . GLN A 1 409 ? -0.714 -6.378 -7.270 1.00 29.54 ? 409 GLN A CG 1 ATOM 3228 C CD . GLN A 1 409 ? 0.791 -6.299 -7.014 1.00 33.93 ? 409 GLN A CD 1 ATOM 3229 O OE1 . GLN A 1 409 ? 1.611 -6.029 -7.921 1.00 36.35 ? 409 GLN A OE1 1 ATOM 3230 N NE2 . GLN A 1 409 ? 1.155 -6.521 -5.771 1.00 38.51 ? 409 GLN A NE2 1 ATOM 3231 N N . THR A 1 410 ? -2.976 -4.964 -10.536 1.00 20.86 ? 410 THR A N 1 ATOM 3232 C CA . THR A 1 410 ? -3.297 -4.415 -11.836 1.00 20.29 ? 410 THR A CA 1 ATOM 3233 C C . THR A 1 410 ? -2.789 -3.017 -11.954 1.00 19.79 ? 410 THR A C 1 ATOM 3234 O O . THR A 1 410 ? -2.608 -2.333 -10.955 1.00 21.56 ? 410 THR A O 1 ATOM 3235 C CB . THR A 1 410 ? -4.846 -4.316 -12.023 1.00 19.89 ? 410 THR A CB 1 ATOM 3236 O OG1 . THR A 1 410 ? -5.395 -3.674 -10.869 1.00 20.87 ? 410 THR A OG1 1 ATOM 3237 C CG2 . THR A 1 410 ? -5.431 -5.684 -12.161 1.00 21.20 ? 410 THR A CG2 1 ATOM 3238 N N . VAL A 1 411 ? -2.566 -2.599 -13.193 1.00 19.79 ? 411 VAL A N 1 ATOM 3239 C CA . VAL A 1 411 ? -2.406 -1.192 -13.540 1.00 18.68 ? 411 VAL A CA 1 ATOM 3240 C C . VAL A 1 411 ? -3.736 -0.715 -14.184 1.00 18.99 ? 411 VAL A C 1 ATOM 3241 O O . VAL A 1 411 ? -4.588 -1.520 -14.519 1.00 20.22 ? 411 VAL A O 1 ATOM 3242 C CB . VAL A 1 411 ? -1.280 -0.986 -14.508 1.00 18.76 ? 411 VAL A CB 1 ATOM 3243 C CG1 . VAL A 1 411 ? 0.083 -1.192 -13.776 1.00 16.81 ? 411 VAL A CG1 1 ATOM 3244 C CG2 . VAL A 1 411 ? -1.423 -1.948 -15.671 1.00 17.84 ? 411 VAL A CG2 1 ATOM 3245 N N . PHE A 1 412 ? -3.870 0.579 -14.368 1.00 19.40 ? 412 PHE A N 1 ATOM 3246 C CA . PHE A 1 412 ? -5.142 1.189 -14.800 1.00 19.99 ? 412 PHE A CA 1 ATOM 3247 C C . PHE A 1 412 ? -4.897 2.042 -16.046 1.00 19.57 ? 412 PHE A C 1 ATOM 3248 O O . PHE A 1 412 ? -4.016 2.897 -16.051 1.00 20.18 ? 412 PHE A O 1 ATOM 3249 C CB . PHE A 1 412 ? -5.692 2.049 -13.646 1.00 19.29 ? 412 PHE A CB 1 ATOM 3250 C CG . PHE A 1 412 ? -6.097 1.243 -12.450 1.00 20.16 ? 412 PHE A CG 1 ATOM 3251 C CD1 . PHE A 1 412 ? -7.393 0.740 -12.354 1.00 18.14 ? 412 PHE A CD1 1 ATOM 3252 C CD2 . PHE A 1 412 ? -5.171 0.954 -11.437 1.00 20.75 ? 412 PHE A CD2 1 ATOM 3253 C CE1 . PHE A 1 412 ? -7.789 -0.032 -11.257 1.00 20.72 ? 412 PHE A CE1 1 ATOM 3254 C CE2 . PHE A 1 412 ? -5.543 0.179 -10.334 1.00 21.25 ? 412 PHE A CE2 1 ATOM 3255 C CZ . PHE A 1 412 ? -6.867 -0.326 -10.247 1.00 21.98 ? 412 PHE A CZ 1 ATOM 3256 N N . PRO A 1 413 ? -5.665 1.806 -17.116 1.00 19.62 ? 413 PRO A N 1 ATOM 3257 C CA . PRO A 1 413 ? -5.463 2.626 -18.282 1.00 19.48 ? 413 PRO A CA 1 ATOM 3258 C C . PRO A 1 413 ? -5.859 4.075 -18.052 1.00 19.94 ? 413 PRO A C 1 ATOM 3259 O O . PRO A 1 413 ? -6.838 4.376 -17.338 1.00 21.16 ? 413 PRO A O 1 ATOM 3260 C CB . PRO A 1 413 ? -6.369 1.979 -19.343 1.00 19.77 ? 413 PRO A CB 1 ATOM 3261 C CG . PRO A 1 413 ? -6.669 0.632 -18.831 1.00 19.86 ? 413 PRO A CG 1 ATOM 3262 C CD . PRO A 1 413 ? -6.693 0.782 -17.333 1.00 18.57 ? 413 PRO A CD 1 ATOM 3263 N N . ASP A 1 414 ? -5.131 4.970 -18.689 1.00 19.00 ? 414 ASP A N 1 ATOM 3264 C CA . ASP A 1 414 ? -5.464 6.388 -18.608 1.00 20.13 ? 414 ASP A CA 1 ATOM 3265 C C . ASP A 1 414 ? -6.249 6.733 -19.868 1.00 19.83 ? 414 ASP A C 1 ATOM 3266 O O . ASP A 1 414 ? -5.680 7.068 -20.911 1.00 19.75 ? 414 ASP A O 1 ATOM 3267 C CB . ASP A 1 414 ? -4.192 7.277 -18.498 1.00 19.89 ? 414 ASP A CB 1 ATOM 3268 C CG . ASP A 1 414 ? -4.508 8.779 -18.674 1.00 22.63 ? 414 ASP A CG 1 ATOM 3269 O OD1 . ASP A 1 414 ? -5.709 9.186 -18.581 1.00 21.16 ? 414 ASP A OD1 1 ATOM 3270 O OD2 . ASP A 1 414 ? -3.584 9.564 -18.947 1.00 21.99 ? 414 ASP A OD2 1 ATOM 3271 N N . TYR A 1 415 ? -7.570 6.645 -19.795 1.00 20.86 ? 415 TYR A N 1 ATOM 3272 C CA . TYR A 1 415 ? -8.348 6.806 -21.019 1.00 20.28 ? 415 TYR A CA 1 ATOM 3273 C C . TYR A 1 415 ? -8.419 8.247 -21.466 1.00 21.55 ? 415 TYR A C 1 ATOM 3274 O O . TYR A 1 415 ? -8.924 8.524 -22.565 1.00 21.22 ? 415 TYR A O 1 ATOM 3275 C CB . TYR A 1 415 ? -9.730 6.200 -20.835 1.00 20.65 ? 415 TYR A CB 1 ATOM 3276 C CG . TYR A 1 415 ? -9.740 4.695 -20.651 1.00 20.13 ? 415 TYR A CG 1 ATOM 3277 C CD1 . TYR A 1 415 ? -9.570 3.837 -21.733 1.00 19.71 ? 415 TYR A CD1 1 ATOM 3278 C CD2 . TYR A 1 415 ? -9.968 4.132 -19.395 1.00 18.07 ? 415 TYR A CD2 1 ATOM 3279 C CE1 . TYR A 1 415 ? -9.629 2.455 -21.578 1.00 18.96 ? 415 TYR A CE1 1 ATOM 3280 C CE2 . TYR A 1 415 ? -10.014 2.757 -19.221 1.00 18.74 ? 415 TYR A CE2 1 ATOM 3281 C CZ . TYR A 1 415 ? -9.835 1.926 -20.320 1.00 19.45 ? 415 TYR A CZ 1 ATOM 3282 O OH . TYR A 1 415 ? -9.888 0.574 -20.130 1.00 19.37 ? 415 TYR A OH 1 ATOM 3283 N N . THR A 1 416 ? -7.895 9.179 -20.654 1.00 20.86 ? 416 THR A N 1 ATOM 3284 C CA . THR A 1 416 ? -7.867 10.591 -21.059 1.00 21.97 ? 416 THR A CA 1 ATOM 3285 C C . THR A 1 416 ? -6.719 10.890 -22.026 1.00 23.48 ? 416 THR A C 1 ATOM 3286 O O . THR A 1 416 ? -6.700 11.938 -22.664 1.00 24.00 ? 416 THR A O 1 ATOM 3287 C CB . THR A 1 416 ? -7.870 11.563 -19.863 1.00 21.69 ? 416 THR A CB 1 ATOM 3288 O OG1 . THR A 1 416 ? -6.581 11.599 -19.233 1.00 22.48 ? 416 THR A OG1 1 ATOM 3289 C CG2 . THR A 1 416 ? -8.929 11.170 -18.853 1.00 21.11 ? 416 THR A CG2 1 ATOM 3290 N N . ASN A 1 417 ? -5.762 9.976 -22.110 1.00 24.11 ? 417 ASN A N 1 ATOM 3291 C CA . ASN A 1 417 ? -4.669 10.070 -23.066 1.00 25.75 ? 417 ASN A CA 1 ATOM 3292 C C . ASN A 1 417 ? -5.188 9.529 -24.407 1.00 27.17 ? 417 ASN A C 1 ATOM 3293 O O . ASN A 1 417 ? -5.609 8.384 -24.474 1.00 26.81 ? 417 ASN A O 1 ATOM 3294 C CB . ASN A 1 417 ? -3.515 9.225 -22.527 1.00 25.17 ? 417 ASN A CB 1 ATOM 3295 C CG . ASN A 1 417 ? -2.284 9.230 -23.428 1.00 27.65 ? 417 ASN A CG 1 ATOM 3296 O OD1 . ASN A 1 417 ? -2.365 9.540 -24.607 1.00 28.17 ? 417 ASN A OD1 1 ATOM 3297 N ND2 . ASN A 1 417 ? -1.136 8.870 -22.856 1.00 27.75 ? 417 ASN A ND2 1 ATOM 3298 N N . PRO A 1 418 ? -5.187 10.359 -25.483 1.00 29.35 ? 418 PRO A N 1 ATOM 3299 C CA . PRO A 1 418 ? -5.608 9.884 -26.831 1.00 30.22 ? 418 PRO A CA 1 ATOM 3300 C C . PRO A 1 418 ? -4.924 8.587 -27.284 1.00 30.05 ? 418 PRO A C 1 ATOM 3301 O O . PRO A 1 418 ? -5.560 7.751 -27.934 1.00 29.32 ? 418 PRO A O 1 ATOM 3302 C CB . PRO A 1 418 ? -5.215 11.041 -27.773 1.00 31.07 ? 418 PRO A CB 1 ATOM 3303 C CG . PRO A 1 418 ? -4.429 12.019 -26.927 1.00 30.89 ? 418 PRO A CG 1 ATOM 3304 C CD . PRO A 1 418 ? -4.818 11.785 -25.496 1.00 29.87 ? 418 PRO A CD 1 ATOM 3305 N N . ASN A 1 419 ? -3.660 8.409 -26.905 1.00 29.66 ? 419 ASN A N 1 ATOM 3306 C CA . ASN A 1 419 ? -2.913 7.202 -27.248 1.00 29.94 ? 419 ASN A CA 1 ATOM 3307 C C . ASN A 1 419 ? -3.436 5.969 -26.535 1.00 28.16 ? 419 ASN A C 1 ATOM 3308 O O . ASN A 1 419 ? -3.220 4.840 -26.980 1.00 27.01 ? 419 ASN A O 1 ATOM 3309 C CB . ASN A 1 419 ? -1.431 7.366 -26.893 1.00 31.09 ? 419 ASN A CB 1 ATOM 3310 C CG . ASN A 1 419 ? -0.707 8.305 -27.844 1.00 36.28 ? 419 ASN A CG 1 ATOM 3311 O OD1 . ASN A 1 419 ? -1.095 8.444 -29.013 1.00 42.47 ? 419 ASN A OD1 1 ATOM 3312 N ND2 . ASN A 1 419 ? 0.346 8.960 -27.353 1.00 39.96 ? 419 ASN A ND2 1 ATOM 3313 N N . CYS A 1 420 ? -4.063 6.182 -25.384 1.00 26.79 ? 420 CYS A N 1 ATOM 3314 C CA . CYS A 1 420 ? -4.687 5.083 -24.681 1.00 25.93 ? 420 CYS A CA 1 ATOM 3315 C C . CYS A 1 420 ? -5.826 4.499 -25.518 1.00 25.80 ? 420 CYS A C 1 ATOM 3316 O O . CYS A 1 420 ? -6.028 3.295 -25.547 1.00 25.42 ? 420 CYS A O 1 ATOM 3317 C CB . CYS A 1 420 ? -5.179 5.515 -23.306 1.00 26.05 ? 420 CYS A CB 1 ATOM 3318 S SG . CYS A 1 420 ? -5.798 4.118 -22.302 1.00 26.51 ? 420 CYS A SG 1 ATOM 3319 N N . ALA A 1 421 ? -6.561 5.355 -26.216 1.00 25.79 ? 421 ALA A N 1 ATOM 3320 C CA . ALA A 1 421 ? -7.614 4.869 -27.093 1.00 25.41 ? 421 ALA A CA 1 ATOM 3321 C C . ALA A 1 421 ? -7.027 4.062 -28.249 1.00 25.33 ? 421 ALA A C 1 ATOM 3322 O O . ALA A 1 421 ? -7.622 3.105 -28.702 1.00 26.18 ? 421 ALA A O 1 ATOM 3323 C CB . ALA A 1 421 ? -8.439 6.011 -27.594 1.00 25.93 ? 421 ALA A CB 1 ATOM 3324 N N . VAL A 1 422 ? -5.834 4.412 -28.716 1.00 25.05 ? 422 VAL A N 1 ATOM 3325 C CA . VAL A 1 422 ? -5.190 3.581 -29.745 1.00 24.06 ? 422 VAL A CA 1 ATOM 3326 C C . VAL A 1 422 ? -4.841 2.188 -29.190 1.00 22.83 ? 422 VAL A C 1 ATOM 3327 O O . VAL A 1 422 ? -5.098 1.178 -29.828 1.00 23.16 ? 422 VAL A O 1 ATOM 3328 C CB . VAL A 1 422 ? -3.924 4.262 -30.305 1.00 24.39 ? 422 VAL A CB 1 ATOM 3329 C CG1 . VAL A 1 422 ? -3.176 3.307 -31.217 1.00 25.18 ? 422 VAL A CG1 1 ATOM 3330 C CG2 . VAL A 1 422 ? -4.291 5.598 -30.987 1.00 24.39 ? 422 VAL A CG2 1 ATOM 3331 N N . TRP A 1 423 ? -4.269 2.140 -27.991 1.00 21.81 ? 423 TRP A N 1 ATOM 3332 C CA . TRP A 1 423 ? -3.962 0.869 -27.340 1.00 21.02 ? 423 TRP A CA 1 ATOM 3333 C C . TRP A 1 423 ? -5.236 0.021 -27.146 1.00 20.06 ? 423 TRP A C 1 ATOM 3334 O O . TRP A 1 423 ? -5.241 -1.168 -27.444 1.00 18.90 ? 423 TRP A O 1 ATOM 3335 C CB . TRP A 1 423 ? -3.264 1.123 -25.989 1.00 21.78 ? 423 TRP A CB 1 ATOM 3336 C CG . TRP A 1 423 ? -3.271 -0.057 -25.069 1.00 22.38 ? 423 TRP A CG 1 ATOM 3337 C CD1 . TRP A 1 423 ? -2.441 -1.139 -25.101 1.00 21.96 ? 423 TRP A CD1 1 ATOM 3338 C CD2 . TRP A 1 423 ? -4.191 -0.278 -23.986 1.00 22.44 ? 423 TRP A CD2 1 ATOM 3339 N NE1 . TRP A 1 423 ? -2.774 -2.023 -24.080 1.00 23.54 ? 423 TRP A NE1 1 ATOM 3340 C CE2 . TRP A 1 423 ? -3.844 -1.510 -23.386 1.00 22.66 ? 423 TRP A CE2 1 ATOM 3341 C CE3 . TRP A 1 423 ? -5.257 0.472 -23.448 1.00 21.74 ? 423 TRP A CE3 1 ATOM 3342 C CZ2 . TRP A 1 423 ? -4.540 -2.033 -22.294 1.00 22.99 ? 423 TRP A CZ2 1 ATOM 3343 C CZ3 . TRP A 1 423 ? -5.949 -0.044 -22.353 1.00 21.64 ? 423 TRP A CZ3 1 ATOM 3344 C CH2 . TRP A 1 423 ? -5.583 -1.290 -21.788 1.00 22.00 ? 423 TRP A CH2 1 ATOM 3345 N N . TRP A 1 424 ? -6.296 0.662 -26.645 1.00 19.17 ? 424 TRP A N 1 ATOM 3346 C CA . TRP A 1 424 ? -7.570 -0.010 -26.325 1.00 19.28 ? 424 TRP A CA 1 ATOM 3347 C C . TRP A 1 424 ? -8.158 -0.579 -27.595 1.00 18.39 ? 424 TRP A C 1 ATOM 3348 O O . TRP A 1 424 ? -8.582 -1.704 -27.622 1.00 19.47 ? 424 TRP A O 1 ATOM 3349 C CB . TRP A 1 424 ? -8.496 1.044 -25.702 1.00 18.45 ? 424 TRP A CB 1 ATOM 3350 C CG . TRP A 1 424 ? -9.780 0.620 -25.017 1.00 19.90 ? 424 TRP A CG 1 ATOM 3351 C CD1 . TRP A 1 424 ? -11.018 1.157 -25.258 1.00 16.90 ? 424 TRP A CD1 1 ATOM 3352 C CD2 . TRP A 1 424 ? -9.944 -0.293 -23.922 1.00 19.18 ? 424 TRP A CD2 1 ATOM 3353 N NE1 . TRP A 1 424 ? -11.951 0.602 -24.416 1.00 18.23 ? 424 TRP A NE1 1 ATOM 3354 C CE2 . TRP A 1 424 ? -11.332 -0.290 -23.584 1.00 20.69 ? 424 TRP A CE2 1 ATOM 3355 C CE3 . TRP A 1 424 ? -9.077 -1.134 -23.207 1.00 17.67 ? 424 TRP A CE3 1 ATOM 3356 C CZ2 . TRP A 1 424 ? -11.861 -1.094 -22.568 1.00 17.88 ? 424 TRP A CZ2 1 ATOM 3357 C CZ3 . TRP A 1 424 ? -9.599 -1.924 -22.183 1.00 18.26 ? 424 TRP A CZ3 1 ATOM 3358 C CH2 . TRP A 1 424 ? -10.987 -1.892 -21.867 1.00 19.78 ? 424 TRP A CH2 1 ATOM 3359 N N . THR A 1 425 ? -8.189 0.214 -28.648 1.00 20.18 ? 425 THR A N 1 ATOM 3360 C CA . THR A 1 425 ? -8.734 -0.239 -29.925 1.00 21.34 ? 425 THR A CA 1 ATOM 3361 C C . THR A 1 425 ? -7.990 -1.477 -30.429 1.00 22.07 ? 425 THR A C 1 ATOM 3362 O O . THR A 1 425 ? -8.610 -2.451 -30.810 1.00 21.34 ? 425 THR A O 1 ATOM 3363 C CB . THR A 1 425 ? -8.646 0.889 -30.996 1.00 21.69 ? 425 THR A CB 1 ATOM 3364 O OG1 . THR A 1 425 ? -9.345 2.049 -30.528 1.00 21.95 ? 425 THR A OG1 1 ATOM 3365 C CG2 . THR A 1 425 ? -9.194 0.435 -32.354 1.00 23.92 ? 425 THR A CG2 1 ATOM 3366 N N . LYS A 1 426 ? -6.651 -1.448 -30.394 1.00 22.88 ? 426 LYS A N 1 ATOM 3367 C CA . LYS A 1 426 ? -5.871 -2.590 -30.862 1.00 23.35 ? 426 LYS A CA 1 ATOM 3368 C C . LYS A 1 426 ? -6.153 -3.823 -30.023 1.00 22.04 ? 426 LYS A C 1 ATOM 3369 O O . LYS A 1 426 ? -6.233 -4.919 -30.571 1.00 22.45 ? 426 LYS A O 1 ATOM 3370 C CB . LYS A 1 426 ? -4.375 -2.268 -30.908 1.00 24.01 ? 426 LYS A CB 1 ATOM 3371 C CG . LYS A 1 426 ? -3.477 -3.396 -31.479 1.00 29.92 ? 426 LYS A CG 1 ATOM 3372 C CD . LYS A 1 426 ? -3.876 -3.788 -32.905 1.00 36.95 ? 426 LYS A CD 1 ATOM 3373 C CE . LYS A 1 426 ? -2.669 -3.920 -33.832 1.00 41.12 ? 426 LYS A CE 1 ATOM 3374 N NZ . LYS A 1 426 ? -3.121 -3.790 -35.264 1.00 42.02 ? 426 LYS A NZ 1 ATOM 3375 N N . GLU A 1 427 ? -6.359 -3.666 -28.709 1.00 22.12 ? 427 GLU A N 1 ATOM 3376 C CA . GLU A 1 427 ? -6.663 -4.837 -27.877 1.00 21.37 ? 427 GLU A CA 1 ATOM 3377 C C . GLU A 1 427 ? -7.999 -5.449 -28.285 1.00 20.89 ? 427 GLU A C 1 ATOM 3378 O O . GLU A 1 427 ? -8.146 -6.664 -28.335 1.00 20.17 ? 427 GLU A O 1 ATOM 3379 C CB . GLU A 1 427 ? -6.680 -4.535 -26.371 1.00 22.21 ? 427 GLU A CB 1 ATOM 3380 C CG . GLU A 1 427 ? -5.359 -4.139 -25.743 1.00 22.92 ? 427 GLU A CG 1 ATOM 3381 C CD . GLU A 1 427 ? -4.218 -5.142 -25.969 1.00 25.23 ? 427 GLU A CD 1 ATOM 3382 O OE1 . GLU A 1 427 ? -4.458 -6.369 -26.058 1.00 27.69 ? 427 GLU A OE1 1 ATOM 3383 O OE2 . GLU A 1 427 ? -3.065 -4.673 -26.070 1.00 27.94 ? 427 GLU A OE2 1 ATOM 3384 N N . PHE A 1 428 ? -8.984 -4.604 -28.580 1.00 20.95 ? 428 PHE A N 1 ATOM 3385 C CA . PHE A 1 428 ? -10.277 -5.138 -29.008 1.00 20.92 ? 428 PHE A CA 1 ATOM 3386 C C . PHE A 1 428 ? -10.182 -5.767 -30.385 1.00 21.13 ? 428 PHE A C 1 ATOM 3387 O O . PHE A 1 428 ? -10.736 -6.786 -30.576 1.00 22.26 ? 428 PHE A O 1 ATOM 3388 C CB . PHE A 1 428 ? -11.325 -4.054 -29.023 1.00 20.35 ? 428 PHE A CB 1 ATOM 3389 C CG . PHE A 1 428 ? -11.926 -3.812 -27.688 1.00 21.25 ? 428 PHE A CG 1 ATOM 3390 C CD1 . PHE A 1 428 ? -12.902 -4.682 -27.182 1.00 25.18 ? 428 PHE A CD1 1 ATOM 3391 C CD2 . PHE A 1 428 ? -11.545 -2.718 -26.931 1.00 24.23 ? 428 PHE A CD2 1 ATOM 3392 C CE1 . PHE A 1 428 ? -13.489 -4.430 -25.923 1.00 24.93 ? 428 PHE A CE1 1 ATOM 3393 C CE2 . PHE A 1 428 ? -12.128 -2.479 -25.683 1.00 23.99 ? 428 PHE A CE2 1 ATOM 3394 C CZ . PHE A 1 428 ? -13.099 -3.332 -25.201 1.00 23.75 ? 428 PHE A CZ 1 ATOM 3395 N N . GLU A 1 429 ? -9.462 -5.154 -31.325 1.00 23.62 ? 429 GLU A N 1 ATOM 3396 C CA . GLU A 1 429 ? -9.259 -5.761 -32.658 1.00 25.79 ? 429 GLU A CA 1 ATOM 3397 C C . GLU A 1 429 ? -8.694 -7.168 -32.534 1.00 24.54 ? 429 GLU A C 1 ATOM 3398 O O . GLU A 1 429 ? -9.188 -8.094 -33.147 1.00 24.71 ? 429 GLU A O 1 ATOM 3399 C CB . GLU A 1 429 ? -8.265 -4.947 -33.492 1.00 25.50 ? 429 GLU A CB 1 ATOM 3400 C CG . GLU A 1 429 ? -8.723 -3.562 -33.949 1.00 30.28 ? 429 GLU A CG 1 ATOM 3401 C CD . GLU A 1 429 ? -7.626 -2.882 -34.795 1.00 31.29 ? 429 GLU A CD 1 ATOM 3402 O OE1 . GLU A 1 429 ? -7.230 -3.515 -35.814 1.00 39.10 ? 429 GLU A OE1 1 ATOM 3403 O OE2 . GLU A 1 429 ? -7.132 -1.762 -34.423 1.00 37.76 ? 429 GLU A OE2 1 ATOM 3404 N N . LEU A 1 430 ? -7.612 -7.315 -31.773 1.00 25.23 ? 430 LEU A N 1 ATOM 3405 C CA . LEU A 1 430 ? -7.010 -8.622 -31.543 1.00 24.64 ? 430 LEU A CA 1 ATOM 3406 C C . LEU A 1 430 ? -7.962 -9.635 -30.912 1.00 24.94 ? 430 LEU A C 1 ATOM 3407 O O . LEU A 1 430 ? -8.027 -10.794 -31.353 1.00 24.40 ? 430 LEU A O 1 ATOM 3408 C CB . LEU A 1 430 ? -5.735 -8.479 -30.700 1.00 26.58 ? 430 LEU A CB 1 ATOM 3409 C CG . LEU A 1 430 ? -4.615 -7.578 -31.265 1.00 27.74 ? 430 LEU A CG 1 ATOM 3410 C CD1 . LEU A 1 430 ? -3.577 -7.299 -30.190 1.00 28.67 ? 430 LEU A CD1 1 ATOM 3411 C CD2 . LEU A 1 430 ? -3.946 -8.125 -32.536 1.00 32.35 ? 430 LEU A CD2 1 ATOM 3412 N N . PHE A 1 431 ? -8.731 -9.231 -29.897 1.00 23.86 ? 431 PHE A N 1 ATOM 3413 C CA . PHE A 1 431 ? -9.647 -10.175 -29.269 1.00 24.05 ? 431 PHE A CA 1 ATOM 3414 C C . PHE A 1 431 ? -10.851 -10.501 -30.146 1.00 24.23 ? 431 PHE A C 1 ATOM 3415 O O . PHE A 1 431 ? -11.394 -11.615 -30.090 1.00 23.85 ? 431 PHE A O 1 ATOM 3416 C CB . PHE A 1 431 ? -10.150 -9.654 -27.934 1.00 23.70 ? 431 PHE A CB 1 ATOM 3417 C CG . PHE A 1 431 ? -10.768 -10.716 -27.074 1.00 23.90 ? 431 PHE A CG 1 ATOM 3418 C CD1 . PHE A 1 431 ? -10.057 -11.893 -26.785 1.00 24.08 ? 431 PHE A CD1 1 ATOM 3419 C CD2 . PHE A 1 431 ? -12.029 -10.526 -26.518 1.00 25.12 ? 431 PHE A CD2 1 ATOM 3420 C CE1 . PHE A 1 431 ? -10.612 -12.858 -25.964 1.00 25.63 ? 431 PHE A CE1 1 ATOM 3421 C CE2 . PHE A 1 431 ? -12.608 -11.488 -25.687 1.00 24.63 ? 431 PHE A CE2 1 ATOM 3422 C CZ . PHE A 1 431 ? -11.917 -12.650 -25.411 1.00 26.21 ? 431 PHE A CZ 1 ATOM 3423 N N . HIS A 1 432 ? -11.287 -9.516 -30.924 1.00 25.02 ? 432 HIS A N 1 ATOM 3424 C CA . HIS A 1 432 ? -12.424 -9.725 -31.824 1.00 26.41 ? 432 HIS A CA 1 ATOM 3425 C C . HIS A 1 432 ? -12.071 -10.729 -32.924 1.00 27.49 ? 432 HIS A C 1 ATOM 3426 O O . HIS A 1 432 ? -12.952 -11.426 -33.423 1.00 26.74 ? 432 HIS A O 1 ATOM 3427 C CB . HIS A 1 432 ? -12.923 -8.419 -32.425 1.00 25.71 ? 432 HIS A CB 1 ATOM 3428 C CG . HIS A 1 432 ? -14.270 -8.541 -33.069 1.00 28.64 ? 432 HIS A CG 1 ATOM 3429 N ND1 . HIS A 1 432 ? -14.437 -8.645 -34.434 1.00 30.17 ? 432 HIS A ND1 1 ATOM 3430 C CD2 . HIS A 1 432 ? -15.515 -8.605 -32.534 1.00 28.73 ? 432 HIS A CD2 1 ATOM 3431 C CE1 . HIS A 1 432 ? -15.726 -8.750 -34.713 1.00 30.51 ? 432 HIS A CE1 1 ATOM 3432 N NE2 . HIS A 1 432 ? -16.402 -8.734 -33.577 1.00 29.83 ? 432 HIS A NE2 1 ATOM 3433 N N . ASN A 1 433 ? -10.781 -10.825 -33.258 1.00 29.13 ? 433 ASN A N 1 ATOM 3434 C CA . ASN A 1 433 ? -10.306 -11.866 -34.179 1.00 31.45 ? 433 ASN A CA 1 ATOM 3435 C C . ASN A 1 433 ? -10.503 -13.289 -33.678 1.00 31.86 ? 433 ASN A C 1 ATOM 3436 O O . ASN A 1 433 ? -10.513 -14.210 -34.478 1.00 33.62 ? 433 ASN A O 1 ATOM 3437 C CB . ASN A 1 433 ? -8.834 -11.643 -34.541 1.00 31.78 ? 433 ASN A CB 1 ATOM 3438 C CG . ASN A 1 433 ? -8.645 -10.410 -35.374 1.00 35.21 ? 433 ASN A CG 1 ATOM 3439 O OD1 . ASN A 1 433 ? -9.622 -9.813 -35.842 1.00 39.02 ? 433 ASN A OD1 1 ATOM 3440 N ND2 . ASN A 1 433 ? -7.401 -9.999 -35.557 1.00 38.26 ? 433 ASN A ND2 1 ATOM 3441 N N . GLN A 1 434 ? -10.647 -13.459 -32.363 1.00 31.47 ? 434 GLN A N 1 ATOM 3442 C CA . GLN A 1 434 ? -10.819 -14.756 -31.727 1.00 31.60 ? 434 GLN A CA 1 ATOM 3443 C C . GLN A 1 434 ? -12.273 -15.003 -31.356 1.00 30.32 ? 434 GLN A C 1 ATOM 3444 O O . GLN A 1 434 ? -12.796 -16.073 -31.596 1.00 29.97 ? 434 GLN A O 1 ATOM 3445 C CB . GLN A 1 434 ? -9.947 -14.855 -30.477 1.00 30.88 ? 434 GLN A CB 1 ATOM 3446 C CG . GLN A 1 434 ? -8.489 -14.448 -30.706 1.00 35.18 ? 434 GLN A CG 1 ATOM 3447 C CD . GLN A 1 434 ? -7.611 -14.646 -29.479 1.00 36.01 ? 434 GLN A CD 1 ATOM 3448 O OE1 . GLN A 1 434 ? -7.383 -13.702 -28.702 1.00 41.81 ? 434 GLN A OE1 1 ATOM 3449 N NE2 . GLN A 1 434 ? -7.107 -15.876 -29.296 1.00 41.15 ? 434 GLN A NE2 1 ATOM 3450 N N . VAL A 1 435 ? -12.917 -14.002 -30.755 1.00 28.94 ? 435 VAL A N 1 ATOM 3451 C CA . VAL A 1 435 ? -14.276 -14.122 -30.240 1.00 27.47 ? 435 VAL A CA 1 ATOM 3452 C C . VAL A 1 435 ? -15.062 -12.972 -30.883 1.00 27.09 ? 435 VAL A C 1 ATOM 3453 O O . VAL A 1 435 ? -14.777 -11.811 -30.608 1.00 26.28 ? 435 VAL A O 1 ATOM 3454 C CB . VAL A 1 435 ? -14.308 -13.971 -28.709 1.00 27.47 ? 435 VAL A CB 1 ATOM 3455 C CG1 . VAL A 1 435 ? -15.730 -14.223 -28.170 1.00 26.88 ? 435 VAL A CG1 1 ATOM 3456 C CG2 . VAL A 1 435 ? -13.305 -14.923 -28.030 1.00 26.98 ? 435 VAL A CG2 1 ATOM 3457 N N . GLU A 1 436 ? -16.021 -13.286 -31.747 1.00 26.23 ? 436 GLU A N 1 ATOM 3458 C CA . GLU A 1 436 ? -16.712 -12.223 -32.522 1.00 26.12 ? 436 GLU A CA 1 ATOM 3459 C C . GLU A 1 436 ? -17.908 -11.629 -31.797 1.00 24.37 ? 436 GLU A C 1 ATOM 3460 O O . GLU A 1 436 ? -19.081 -11.823 -32.202 1.00 23.44 ? 436 GLU A O 1 ATOM 3461 C CB . GLU A 1 436 ? -17.106 -12.710 -33.906 1.00 26.67 ? 436 GLU A CB 1 ATOM 3462 C CG . GLU A 1 436 ? -15.881 -12.902 -34.792 1.00 33.24 ? 436 GLU A CG 1 ATOM 3463 C CD . GLU A 1 436 ? -16.233 -13.112 -36.250 1.00 41.70 ? 436 GLU A CD 1 ATOM 3464 O OE1 . GLU A 1 436 ? -17.430 -13.377 -36.573 1.00 42.39 ? 436 GLU A OE1 1 ATOM 3465 O OE2 . GLU A 1 436 ? -15.284 -13.017 -37.067 1.00 44.19 ? 436 GLU A OE2 1 ATOM 3466 N N . PHE A 1 437 ? -17.590 -10.961 -30.694 1.00 22.97 ? 437 PHE A N 1 ATOM 3467 C CA . PHE A 1 437 ? -18.582 -10.273 -29.838 1.00 21.84 ? 437 PHE A CA 1 ATOM 3468 C C . PHE A 1 437 ? -19.203 -9.095 -30.602 1.00 20.93 ? 437 PHE A C 1 ATOM 3469 O O . PHE A 1 437 ? -18.588 -8.560 -31.520 1.00 20.01 ? 437 PHE A O 1 ATOM 3470 C CB . PHE A 1 437 ? -17.947 -9.810 -28.507 1.00 21.09 ? 437 PHE A CB 1 ATOM 3471 C CG . PHE A 1 437 ? -16.792 -8.891 -28.695 1.00 21.22 ? 437 PHE A CG 1 ATOM 3472 C CD1 . PHE A 1 437 ? -16.986 -7.523 -28.861 1.00 18.54 ? 437 PHE A CD1 1 ATOM 3473 C CD2 . PHE A 1 437 ? -15.501 -9.406 -28.783 1.00 20.29 ? 437 PHE A CD2 1 ATOM 3474 C CE1 . PHE A 1 437 ? -15.919 -6.661 -29.081 1.00 22.40 ? 437 PHE A CE1 1 ATOM 3475 C CE2 . PHE A 1 437 ? -14.423 -8.545 -29.015 1.00 18.18 ? 437 PHE A CE2 1 ATOM 3476 C CZ . PHE A 1 437 ? -14.647 -7.174 -29.167 1.00 20.35 ? 437 PHE A CZ 1 ATOM 3477 N N . ASP A 1 438 ? -20.405 -8.680 -30.188 1.00 19.38 ? 438 ASP A N 1 ATOM 3478 C CA . ASP A 1 438 ? -21.181 -7.667 -30.910 1.00 18.71 ? 438 ASP A CA 1 ATOM 3479 C C . ASP A 1 438 ? -21.309 -6.345 -30.141 1.00 17.36 ? 438 ASP A C 1 ATOM 3480 O O . ASP A 1 438 ? -21.648 -5.322 -30.704 1.00 17.17 ? 438 ASP A O 1 ATOM 3481 C CB . ASP A 1 438 ? -22.572 -8.216 -31.114 1.00 19.09 ? 438 ASP A CB 1 ATOM 3482 C CG . ASP A 1 438 ? -22.557 -9.456 -31.953 1.00 20.17 ? 438 ASP A CG 1 ATOM 3483 O OD1 . ASP A 1 438 ? -22.218 -9.326 -33.153 1.00 20.92 ? 438 ASP A OD1 1 ATOM 3484 O OD2 . ASP A 1 438 ? -22.824 -10.538 -31.405 1.00 22.24 ? 438 ASP A OD2 1 ATOM 3485 N N . GLY A 1 439 ? -21.077 -6.399 -28.841 1.00 17.77 ? 439 GLY A N 1 ATOM 3486 C CA . GLY A 1 439 ? -21.121 -5.208 -27.983 1.00 17.05 ? 439 GLY A CA 1 ATOM 3487 C C . GLY A 1 439 ? -20.242 -5.408 -26.753 1.00 17.81 ? 439 GLY A C 1 ATOM 3488 O O . GLY A 1 439 ? -19.736 -6.520 -26.516 1.00 18.41 ? 439 GLY A O 1 ATOM 3489 N N . ILE A 1 440 ? -20.083 -4.339 -25.973 1.00 17.72 ? 440 ILE A N 1 ATOM 3490 C CA . ILE A 1 440 ? -19.090 -4.291 -24.904 1.00 18.07 ? 440 ILE A CA 1 ATOM 3491 C C . ILE A 1 440 ? -19.762 -3.738 -23.656 1.00 17.63 ? 440 ILE A C 1 ATOM 3492 O O . ILE A 1 440 ? -20.508 -2.762 -23.707 1.00 17.45 ? 440 ILE A O 1 ATOM 3493 C CB . ILE A 1 440 ? -17.892 -3.409 -25.289 1.00 18.74 ? 440 ILE A CB 1 ATOM 3494 C CG1 . ILE A 1 440 ? -17.199 -3.968 -26.562 1.00 19.62 ? 440 ILE A CG1 1 ATOM 3495 C CG2 . ILE A 1 440 ? -16.891 -3.344 -24.132 1.00 21.60 ? 440 ILE A CG2 1 ATOM 3496 C CD1 . ILE A 1 440 ? -16.376 -2.914 -27.339 1.00 23.80 ? 440 ILE A CD1 1 ATOM 3497 N N . TRP A 1 441 ? -19.491 -4.391 -22.537 1.00 16.13 ? 441 TRP A N 1 ATOM 3498 C CA . TRP A 1 441 ? -20.058 -4.022 -21.266 1.00 16.85 ? 441 TRP A CA 1 ATOM 3499 C C . TRP A 1 441 ? -18.862 -3.596 -20.434 1.00 17.06 ? 441 TRP A C 1 ATOM 3500 O O . TRP A 1 441 ? -18.040 -4.430 -20.094 1.00 17.08 ? 441 TRP A O 1 ATOM 3501 C CB . TRP A 1 441 ? -20.784 -5.241 -20.719 1.00 17.35 ? 441 TRP A CB 1 ATOM 3502 C CG . TRP A 1 441 ? -21.126 -5.224 -19.294 1.00 16.78 ? 441 TRP A CG 1 ATOM 3503 C CD1 . TRP A 1 441 ? -21.169 -4.138 -18.460 1.00 19.02 ? 441 TRP A CD1 1 ATOM 3504 C CD2 . TRP A 1 441 ? -21.514 -6.352 -18.515 1.00 19.07 ? 441 TRP A CD2 1 ATOM 3505 N NE1 . TRP A 1 441 ? -21.550 -4.530 -17.193 1.00 21.68 ? 441 TRP A NE1 1 ATOM 3506 C CE2 . TRP A 1 441 ? -21.780 -5.881 -17.199 1.00 20.34 ? 441 TRP A CE2 1 ATOM 3507 C CE3 . TRP A 1 441 ? -21.683 -7.726 -18.799 1.00 18.32 ? 441 TRP A CE3 1 ATOM 3508 C CZ2 . TRP A 1 441 ? -22.190 -6.734 -16.165 1.00 20.45 ? 441 TRP A CZ2 1 ATOM 3509 C CZ3 . TRP A 1 441 ? -22.055 -8.580 -17.765 1.00 18.44 ? 441 TRP A CZ3 1 ATOM 3510 C CH2 . TRP A 1 441 ? -22.283 -8.074 -16.453 1.00 18.33 ? 441 TRP A CH2 1 ATOM 3511 N N . ILE A 1 442 ? -18.727 -2.294 -20.206 1.00 17.20 ? 442 ILE A N 1 ATOM 3512 C CA . ILE A 1 442 ? -17.607 -1.734 -19.401 1.00 18.32 ? 442 ILE A CA 1 ATOM 3513 C C . ILE A 1 442 ? -18.055 -1.526 -17.961 1.00 19.29 ? 442 ILE A C 1 ATOM 3514 O O . ILE A 1 442 ? -19.118 -0.892 -17.677 1.00 20.13 ? 442 ILE A O 1 ATOM 3515 C CB . ILE A 1 442 ? -16.935 -0.479 -20.037 1.00 19.02 ? 442 ILE A CB 1 ATOM 3516 C CG1 . ILE A 1 442 ? -17.958 0.652 -20.289 1.00 17.14 ? 442 ILE A CG1 1 ATOM 3517 C CG2 . ILE A 1 442 ? -16.171 -0.866 -21.343 1.00 17.73 ? 442 ILE A CG2 1 ATOM 3518 C CD1 . ILE A 1 442 ? -17.338 1.954 -20.845 1.00 19.32 ? 442 ILE A CD1 1 ATOM 3519 N N . ASP A 1 443 ? -17.320 -2.169 -17.060 1.00 19.23 ? 443 ASP A N 1 ATOM 3520 C CA . ASP A 1 443 ? -17.686 -2.281 -15.670 1.00 20.15 ? 443 ASP A CA 1 ATOM 3521 C C . ASP A 1 443 ? -16.502 -1.859 -14.766 1.00 20.53 ? 443 ASP A C 1 ATOM 3522 O O . ASP A 1 443 ? -15.391 -1.677 -15.258 1.00 20.22 ? 443 ASP A O 1 ATOM 3523 C CB . ASP A 1 443 ? -18.024 -3.729 -15.405 1.00 20.78 ? 443 ASP A CB 1 ATOM 3524 C CG . ASP A 1 443 ? -18.601 -3.950 -14.035 1.00 23.48 ? 443 ASP A CG 1 ATOM 3525 O OD1 . ASP A 1 443 ? -19.281 -3.028 -13.516 1.00 23.79 ? 443 ASP A OD1 1 ATOM 3526 O OD2 . ASP A 1 443 ? -18.335 -5.039 -13.476 1.00 27.53 ? 443 ASP A OD2 1 ATOM 3527 N N . MET A 1 444 ? -16.766 -1.709 -13.465 1.00 20.24 ? 444 MET A N 1 ATOM 3528 C CA . MET A 1 444 ? -15.720 -1.414 -12.462 1.00 20.46 ? 444 MET A CA 1 ATOM 3529 C C . MET A 1 444 ? -15.005 -0.108 -12.795 1.00 19.93 ? 444 MET A C 1 ATOM 3530 O O . MET A 1 444 ? -13.838 0.082 -12.441 1.00 19.07 ? 444 MET A O 1 ATOM 3531 C CB . MET A 1 444 ? -14.702 -2.557 -12.435 1.00 20.92 ? 444 MET A CB 1 ATOM 3532 C CG . MET A 1 444 ? -15.270 -3.938 -12.228 1.00 22.38 ? 444 MET A CG 1 ATOM 3533 S SD . MET A 1 444 ? -16.183 -4.089 -10.687 1.00 27.23 ? 444 MET A SD 1 ATOM 3534 C CE . MET A 1 444 ? -14.751 -4.150 -9.568 1.00 19.05 ? 444 MET A CE 1 ATOM 3535 N N . ASN A 1 445 ? -15.680 0.788 -13.527 1.00 18.49 ? 445 ASN A N 1 ATOM 3536 C CA . ASN A 1 445 ? -14.980 1.945 -14.107 1.00 16.84 ? 445 ASN A CA 1 ATOM 3537 C C . ASN A 1 445 ? -15.233 3.278 -13.395 1.00 17.04 ? 445 ASN A C 1 ATOM 3538 O O . ASN A 1 445 ? -15.169 4.341 -13.989 1.00 16.95 ? 445 ASN A O 1 ATOM 3539 C CB . ASN A 1 445 ? -15.190 2.029 -15.611 1.00 15.54 ? 445 ASN A CB 1 ATOM 3540 C CG . ASN A 1 445 ? -16.687 2.149 -15.986 1.00 17.01 ? 445 ASN A CG 1 ATOM 3541 O OD1 . ASN A 1 445 ? -17.559 2.058 -15.148 1.00 17.05 ? 445 ASN A OD1 1 ATOM 3542 N ND2 . ASN A 1 445 ? -16.943 2.401 -17.244 1.00 16.45 ? 445 ASN A ND2 1 ATOM 3543 N N . GLU A 1 446 ? -15.425 3.202 -12.090 1.00 16.92 ? 446 GLU A N 1 ATOM 3544 C CA . GLU A 1 446 ? -15.503 4.416 -11.255 1.00 18.73 ? 446 GLU A CA 1 ATOM 3545 C C . GLU A 1 446 ? -14.244 5.260 -11.082 1.00 20.39 ? 446 GLU A C 1 ATOM 3546 O O . GLU A 1 446 ? -14.364 6.474 -10.951 1.00 20.98 ? 446 GLU A O 1 ATOM 3547 C CB . GLU A 1 446 ? -16.064 4.072 -9.871 1.00 19.16 ? 446 GLU A CB 1 ATOM 3548 C CG . GLU A 1 446 ? -17.536 3.621 -9.899 1.00 18.60 ? 446 GLU A CG 1 ATOM 3549 C CD . GLU A 1 446 ? -17.784 2.240 -10.557 1.00 25.65 ? 446 GLU A CD 1 ATOM 3550 O OE1 . GLU A 1 446 ? -16.936 1.331 -10.412 1.00 23.04 ? 446 GLU A OE1 1 ATOM 3551 O OE2 . GLU A 1 446 ? -18.870 2.065 -11.210 1.00 27.51 ? 446 GLU A OE2 1 ATOM 3552 N N . VAL A 1 447 ? -13.024 4.699 -11.029 1.00 21.47 ? 447 VAL A N 1 ATOM 3553 C CA . VAL A 1 447 ? -12.659 3.324 -11.209 1.00 22.79 ? 447 VAL A CA 1 ATOM 3554 C C . VAL A 1 447 ? -12.670 2.570 -9.850 1.00 23.72 ? 447 VAL A C 1 ATOM 3555 O O . VAL A 1 447 ? -12.422 3.155 -8.793 1.00 24.65 ? 447 VAL A O 1 ATOM 3556 C CB . VAL A 1 447 ? -11.284 3.292 -11.948 1.00 23.57 ? 447 VAL A CB 1 ATOM 3557 C CG1 . VAL A 1 447 ? -10.180 3.703 -11.038 1.00 26.57 ? 447 VAL A CG1 1 ATOM 3558 C CG2 . VAL A 1 447 ? -11.027 1.932 -12.546 1.00 25.72 ? 447 VAL A CG2 1 ATOM 3559 N N . SER A 1 448 ? -13.059 1.301 -9.873 1.00 23.02 ? 448 SER A N 1 ATOM 3560 C CA . SER A 1 448 ? -13.165 0.496 -8.669 1.00 24.03 ? 448 SER A CA 1 ATOM 3561 C C . SER A 1 448 ? -11.806 -0.187 -8.401 1.00 23.41 ? 448 SER A C 1 ATOM 3562 O O . SER A 1 448 ? -11.140 -0.666 -9.340 1.00 23.96 ? 448 SER A O 1 ATOM 3563 C CB . SER A 1 448 ? -14.315 -0.491 -8.820 1.00 24.55 ? 448 SER A CB 1 ATOM 3564 O OG . SER A 1 448 ? -14.460 -1.323 -7.683 1.00 29.30 ? 448 SER A OG 1 ATOM 3565 N N . ASN A 1 449 ? -11.377 -0.151 -7.143 1.00 21.44 ? 449 ASN A N 1 ATOM 3566 C CA . ASN A 1 449 ? -10.081 -0.710 -6.687 1.00 21.21 ? 449 ASN A CA 1 ATOM 3567 C C . ASN A 1 449 ? -10.392 -1.535 -5.420 1.00 21.61 ? 449 ASN A C 1 ATOM 3568 O O . ASN A 1 449 ? -11.218 -1.121 -4.559 1.00 22.25 ? 449 ASN A O 1 ATOM 3569 C CB . ASN A 1 449 ? -9.127 0.446 -6.400 1.00 20.12 ? 449 ASN A CB 1 ATOM 3570 C CG . ASN A 1 449 ? -7.661 0.024 -6.289 1.00 21.42 ? 449 ASN A CG 1 ATOM 3571 O OD1 . ASN A 1 449 ? -7.316 -1.147 -6.375 1.00 20.91 ? 449 ASN A OD1 1 ATOM 3572 N ND2 . ASN A 1 449 ? -6.801 1.002 -6.095 1.00 20.96 ? 449 ASN A ND2 1 ATOM 3573 N N . PHE A 1 450 ? -9.858 -2.748 -5.343 1.00 21.14 ? 450 PHE A N 1 ATOM 3574 C CA . PHE A 1 450 ? -10.118 -3.616 -4.195 1.00 22.12 ? 450 PHE A CA 1 ATOM 3575 C C . PHE A 1 450 ? -9.221 -3.239 -3.015 1.00 23.35 ? 450 PHE A C 1 ATOM 3576 O O . PHE A 1 450 ? -9.421 -3.729 -1.910 1.00 24.23 ? 450 PHE A O 1 ATOM 3577 C CB . PHE A 1 450 ? -9.922 -5.103 -4.546 1.00 21.65 ? 450 PHE A CB 1 ATOM 3578 C CG . PHE A 1 450 ? -10.980 -5.658 -5.484 1.00 21.72 ? 450 PHE A CG 1 ATOM 3579 C CD1 . PHE A 1 450 ? -12.145 -4.938 -5.757 1.00 22.01 ? 450 PHE A CD1 1 ATOM 3580 C CD2 . PHE A 1 450 ? -10.820 -6.913 -6.057 1.00 23.75 ? 450 PHE A CD2 1 ATOM 3581 C CE1 . PHE A 1 450 ? -13.117 -5.445 -6.609 1.00 22.34 ? 450 PHE A CE1 1 ATOM 3582 C CE2 . PHE A 1 450 ? -11.810 -7.434 -6.908 1.00 24.31 ? 450 PHE A CE2 1 ATOM 3583 C CZ . PHE A 1 450 ? -12.948 -6.693 -7.180 1.00 22.23 ? 450 PHE A CZ 1 ATOM 3584 N N . VAL A 1 451 ? -8.231 -2.394 -3.270 1.00 23.12 ? 451 VAL A N 1 ATOM 3585 C CA . VAL A 1 451 ? -7.463 -1.750 -2.214 1.00 23.55 ? 451 VAL A CA 1 ATOM 3586 C C . VAL A 1 451 ? -7.810 -0.254 -2.218 1.00 23.71 ? 451 VAL A C 1 ATOM 3587 O O . VAL A 1 451 ? -8.251 0.273 -3.229 1.00 23.01 ? 451 VAL A O 1 ATOM 3588 C CB . VAL A 1 451 ? -5.906 -1.970 -2.393 1.00 22.93 ? 451 VAL A CB 1 ATOM 3589 C CG1 . VAL A 1 451 ? -5.558 -3.425 -2.267 1.00 24.38 ? 451 VAL A CG1 1 ATOM 3590 C CG2 . VAL A 1 451 ? -5.410 -1.429 -3.732 1.00 22.85 ? 451 VAL A CG2 1 ATOM 3591 N N . ASP A 1 452 ? -7.614 0.432 -1.093 1.00 23.95 ? 452 ASP A N 1 ATOM 3592 C CA . ASP A 1 452 ? -7.896 1.846 -1.033 1.00 24.49 ? 452 ASP A CA 1 ATOM 3593 C C . ASP A 1 452 ? -6.708 2.617 -1.575 1.00 24.47 ? 452 ASP A C 1 ATOM 3594 O O . ASP A 1 452 ? -5.647 2.625 -0.948 1.00 24.88 ? 452 ASP A O 1 ATOM 3595 C CB . ASP A 1 452 ? -8.228 2.245 0.407 1.00 24.90 ? 452 ASP A CB 1 ATOM 3596 C CG . ASP A 1 452 ? -9.564 1.654 0.888 1.00 28.29 ? 452 ASP A CG 1 ATOM 3597 O OD1 . ASP A 1 452 ? -10.402 1.214 0.048 1.00 27.30 ? 452 ASP A OD1 1 ATOM 3598 O OD2 . ASP A 1 452 ? -9.780 1.637 2.129 1.00 32.28 ? 452 ASP A OD2 1 ATOM 3599 N N . GLY A 1 453 ? -6.856 3.213 -2.762 1.00 22.72 ? 453 GLY A N 1 ATOM 3600 C CA . GLY A 1 453 ? -5.824 4.058 -3.342 1.00 22.69 ? 453 GLY A CA 1 ATOM 3601 C C . GLY A 1 453 ? -4.816 3.319 -4.209 1.00 23.37 ? 453 GLY A C 1 ATOM 3602 O O . GLY A 1 453 ? -4.742 3.496 -5.419 1.00 22.83 ? 453 GLY A O 1 ATOM 3603 N N . SER A 1 454 ? -4.018 2.476 -3.583 1.00 23.61 ? 454 SER A N 1 ATOM 3604 C CA . SER A 1 454 ? -3.084 1.670 -4.327 1.00 24.47 ? 454 SER A CA 1 ATOM 3605 C C . SER A 1 454 ? -2.613 0.575 -3.375 1.00 24.82 ? 454 SER A C 1 ATOM 3606 O O . SER A 1 454 ? -2.993 0.568 -2.195 1.00 24.86 ? 454 SER A O 1 ATOM 3607 C CB . SER A 1 454 ? -1.919 2.522 -4.788 1.00 24.80 ? 454 SER A CB 1 ATOM 3608 O OG . SER A 1 454 ? -1.040 2.784 -3.699 1.00 28.78 ? 454 SER A OG 1 ATOM 3609 N N . VAL A 1 455 ? -1.836 -0.369 -3.891 1.00 25.38 ? 455 VAL A N 1 ATOM 3610 C CA . VAL A 1 455 ? -1.297 -1.440 -3.060 1.00 26.15 ? 455 VAL A CA 1 ATOM 3611 C C . VAL A 1 455 ? -0.397 -0.886 -1.925 1.00 27.14 ? 455 VAL A C 1 ATOM 3612 O O . VAL A 1 455 ? -0.123 -1.567 -0.938 1.00 27.55 ? 455 VAL A O 1 ATOM 3613 C CB . VAL A 1 455 ? -0.588 -2.541 -3.909 1.00 26.39 ? 455 VAL A CB 1 ATOM 3614 C CG1 . VAL A 1 455 ? -1.570 -3.199 -4.893 1.00 24.35 ? 455 VAL A CG1 1 ATOM 3615 C CG2 . VAL A 1 455 ? 0.685 -2.030 -4.617 1.00 26.12 ? 455 VAL A CG2 1 ATOM 3616 N N . SER A 1 456 ? 0.016 0.359 -2.033 1.00 27.61 ? 456 SER A N 1 ATOM 3617 C CA . SER A 1 456 ? 0.764 0.967 -0.941 1.00 29.99 ? 456 SER A CA 1 ATOM 3618 C C . SER A 1 456 ? 0.008 2.127 -0.262 1.00 29.24 ? 456 SER A C 1 ATOM 3619 O O . SER A 1 456 ? 0.592 2.987 0.376 1.00 31.00 ? 456 SER A O 1 ATOM 3620 C CB . SER A 1 456 ? 2.171 1.315 -1.399 1.00 29.41 ? 456 SER A CB 1 ATOM 3621 O OG . SER A 1 456 ? 2.166 2.486 -2.169 1.00 34.04 ? 456 SER A OG 1 ATOM 3622 N N . GLY A 1 457 ? -1.315 2.107 -0.351 1.00 28.94 ? 457 GLY A N 1 ATOM 3623 C CA . GLY A 1 457 ? -2.135 3.176 0.205 1.00 28.18 ? 457 GLY A CA 1 ATOM 3624 C C . GLY A 1 457 ? -1.924 4.506 -0.499 1.00 28.37 ? 457 GLY A C 1 ATOM 3625 O O . GLY A 1 457 ? -1.548 4.544 -1.669 1.00 28.16 ? 457 GLY A O 1 ATOM 3626 N N . CYS A 1 458 ? -2.165 5.598 0.231 1.00 27.97 ? 458 CYS A N 1 ATOM 3627 C CA . CYS A 1 458 ? -2.081 6.963 -0.295 1.00 27.88 ? 458 CYS A CA 1 ATOM 3628 C C . CYS A 1 458 ? -1.333 7.853 0.663 1.00 26.98 ? 458 CYS A C 1 ATOM 3629 O O . CYS A 1 458 ? -1.584 7.788 1.850 1.00 27.50 ? 458 CYS A O 1 ATOM 3630 C CB . CYS A 1 458 ? -3.475 7.582 -0.356 1.00 27.99 ? 458 CYS A CB 1 ATOM 3631 S SG . CYS A 1 458 ? -4.614 6.638 -1.293 1.00 32.07 ? 458 CYS A SG 1 ATOM 3632 N N . SER A 1 459 ? -0.517 8.754 0.151 1.00 27.04 ? 459 SER A N 1 ATOM 3633 C CA . SER A 1 459 ? 0.141 9.736 1.027 1.00 28.15 ? 459 SER A CA 1 ATOM 3634 C C . SER A 1 459 ? -0.845 10.689 1.667 1.00 27.37 ? 459 SER A C 1 ATOM 3635 O O . SER A 1 459 ? -1.882 11.018 1.094 1.00 26.83 ? 459 SER A O 1 ATOM 3636 C CB . SER A 1 459 ? 1.193 10.536 0.270 1.00 28.41 ? 459 SER A CB 1 ATOM 3637 O OG . SER A 1 459 ? 1.968 9.630 -0.492 1.00 33.27 ? 459 SER A OG 1 ATOM 3638 N N . THR A 1 460 ? -0.528 11.125 2.878 1.00 26.77 ? 460 THR A N 1 ATOM 3639 C CA . THR A 1 460 ? -1.380 12.088 3.557 1.00 26.70 ? 460 THR A CA 1 ATOM 3640 C C . THR A 1 460 ? -1.012 13.418 2.928 1.00 26.39 ? 460 THR A C 1 ATOM 3641 O O . THR A 1 460 ? 0.154 13.801 2.909 1.00 26.86 ? 460 THR A O 1 ATOM 3642 C CB . THR A 1 460 ? -1.121 12.113 5.074 1.00 27.30 ? 460 THR A CB 1 ATOM 3643 O OG1 . THR A 1 460 ? -1.338 10.800 5.622 1.00 24.84 ? 460 THR A OG1 1 ATOM 3644 C CG2 . THR A 1 460 ? -2.048 13.151 5.759 1.00 26.68 ? 460 THR A CG2 1 ATOM 3645 N N . ASN A 1 461 ? -1.996 14.099 2.349 1.00 23.59 ? 461 ASN A N 1 ATOM 3646 C CA . ASN A 1 461 ? -1.749 15.377 1.692 1.00 22.19 ? 461 ASN A CA 1 ATOM 3647 C C . ASN A 1 461 ? -3.115 15.992 1.408 1.00 22.00 ? 461 ASN A C 1 ATOM 3648 O O . ASN A 1 461 ? -4.116 15.358 1.710 1.00 20.69 ? 461 ASN A O 1 ATOM 3649 C CB . ASN A 1 461 ? -0.890 15.231 0.425 1.00 22.29 ? 461 ASN A CB 1 ATOM 3650 C CG . ASN A 1 461 ? -1.529 14.389 -0.648 1.00 23.29 ? 461 ASN A CG 1 ATOM 3651 O OD1 . ASN A 1 461 ? -2.745 14.504 -0.930 1.00 22.92 ? 461 ASN A OD1 1 ATOM 3652 N ND2 . ASN A 1 461 ? -0.718 13.560 -1.289 1.00 21.74 ? 461 ASN A ND2 1 ATOM 3653 N N . ASN A 1 462 ? -3.159 17.194 0.840 1.00 21.42 ? 462 ASN A N 1 ATOM 3654 C CA . ASN A 1 462 ? -4.444 17.914 0.742 1.00 21.86 ? 462 ASN A CA 1 ATOM 3655 C C . ASN A 1 462 ? -5.422 17.354 -0.302 1.00 20.27 ? 462 ASN A C 1 ATOM 3656 O O . ASN A 1 462 ? -6.605 17.714 -0.297 1.00 21.36 ? 462 ASN A O 1 ATOM 3657 C CB . ASN A 1 462 ? -4.220 19.397 0.524 1.00 22.90 ? 462 ASN A CB 1 ATOM 3658 C CG . ASN A 1 462 ? -3.553 19.698 -0.796 1.00 29.05 ? 462 ASN A CG 1 ATOM 3659 O OD1 . ASN A 1 462 ? -2.492 19.127 -1.139 1.00 34.70 ? 462 ASN A OD1 1 ATOM 3660 N ND2 . ASN A 1 462 ? -4.156 20.615 -1.564 1.00 33.23 ? 462 ASN A ND2 1 ATOM 3661 N N . LEU A 1 463 ? -4.916 16.502 -1.180 1.00 20.48 ? 463 LEU A N 1 ATOM 3662 C CA . LEU A 1 463 ? -5.701 15.811 -2.219 1.00 18.99 ? 463 LEU A CA 1 ATOM 3663 C C . LEU A 1 463 ? -6.320 14.550 -1.646 1.00 20.07 ? 463 LEU A C 1 ATOM 3664 O O . LEU A 1 463 ? -7.556 14.354 -1.738 1.00 18.71 ? 463 LEU A O 1 ATOM 3665 C CB . LEU A 1 463 ? -4.854 15.496 -3.452 1.00 19.40 ? 463 LEU A CB 1 ATOM 3666 C CG . LEU A 1 463 ? -4.207 16.712 -4.145 1.00 19.81 ? 463 LEU A CG 1 ATOM 3667 C CD1 . LEU A 1 463 ? -3.711 16.292 -5.508 1.00 20.34 ? 463 LEU A CD1 1 ATOM 3668 C CD2 . LEU A 1 463 ? -5.190 17.832 -4.315 1.00 24.39 ? 463 LEU A CD2 1 ATOM 3669 N N . ASN A 1 464 ? -5.501 13.714 -0.998 1.00 18.52 ? 464 ASN A N 1 ATOM 3670 C CA . ASN A 1 464 ? -6.027 12.488 -0.359 1.00 20.01 ? 464 ASN A CA 1 ATOM 3671 C C . ASN A 1 464 ? -6.819 12.767 0.900 1.00 19.88 ? 464 ASN A C 1 ATOM 3672 O O . ASN A 1 464 ? -7.737 12.034 1.255 1.00 20.18 ? 464 ASN A O 1 ATOM 3673 C CB . ASN A 1 464 ? -4.894 11.482 -0.061 1.00 19.55 ? 464 ASN A CB 1 ATOM 3674 C CG . ASN A 1 464 ? -4.287 10.916 -1.303 1.00 22.62 ? 464 ASN A CG 1 ATOM 3675 O OD1 . ASN A 1 464 ? -3.054 10.800 -1.413 1.00 27.54 ? 464 ASN A OD1 1 ATOM 3676 N ND2 . ASN A 1 464 ? -5.123 10.551 -2.260 1.00 21.47 ? 464 ASN A ND2 1 ATOM 3677 N N . ASN A 1 465 ? -6.463 13.853 1.571 1.00 20.77 ? 465 ASN A N 1 ATOM 3678 C CA . ASN A 1 465 ? -7.106 14.260 2.820 1.00 21.80 ? 465 ASN A CA 1 ATOM 3679 C C . ASN A 1 465 ? -7.458 15.743 2.792 1.00 21.71 ? 465 ASN A C 1 ATOM 3680 O O . ASN A 1 465 ? -6.723 16.581 3.331 1.00 20.86 ? 465 ASN A O 1 ATOM 3681 C CB . ASN A 1 465 ? -6.187 13.929 4.011 1.00 22.52 ? 465 ASN A CB 1 ATOM 3682 C CG . ASN A 1 465 ? -5.805 12.463 4.040 1.00 23.24 ? 465 ASN A CG 1 ATOM 3683 O OD1 . ASN A 1 465 ? -6.517 11.653 4.617 1.00 25.17 ? 465 ASN A OD1 1 ATOM 3684 N ND2 . ASN A 1 465 ? -4.680 12.116 3.400 1.00 22.73 ? 465 ASN A ND2 1 ATOM 3685 N N . PRO A 1 466 ? -8.573 16.095 2.121 1.00 20.56 ? 466 PRO A N 1 ATOM 3686 C CA . PRO A 1 466 ? -8.812 17.518 1.913 1.00 20.54 ? 466 PRO A CA 1 ATOM 3687 C C . PRO A 1 466 ? -9.409 18.188 3.157 1.00 20.26 ? 466 PRO A C 1 ATOM 3688 O O . PRO A 1 466 ? -9.857 17.487 4.061 1.00 21.58 ? 466 PRO A O 1 ATOM 3689 C CB . PRO A 1 466 ? -9.808 17.518 0.716 1.00 19.80 ? 466 PRO A CB 1 ATOM 3690 C CG . PRO A 1 466 ? -10.603 16.268 0.930 1.00 20.13 ? 466 PRO A CG 1 ATOM 3691 C CD . PRO A 1 466 ? -9.610 15.255 1.475 1.00 21.40 ? 466 PRO A CD 1 ATOM 3692 N N . PRO A 1 467 ? -9.424 19.532 3.203 1.00 20.65 ? 467 PRO A N 1 ATOM 3693 C CA . PRO A 1 467 ? -9.979 20.269 4.346 1.00 20.72 ? 467 PRO A CA 1 ATOM 3694 C C . PRO A 1 467 ? -11.463 19.949 4.606 1.00 21.59 ? 467 PRO A C 1 ATOM 3695 O O . PRO A 1 467 ? -11.906 19.898 5.761 1.00 21.97 ? 467 PRO A O 1 ATOM 3696 C CB . PRO A 1 467 ? -9.759 21.742 3.984 1.00 20.98 ? 467 PRO A CB 1 ATOM 3697 C CG . PRO A 1 467 ? -9.191 21.776 2.600 1.00 21.23 ? 467 PRO A CG 1 ATOM 3698 C CD . PRO A 1 467 ? -8.850 20.406 2.158 1.00 20.50 ? 467 PRO A CD 1 ATOM 3699 N N . PHE A 1 468 ? -12.224 19.703 3.535 1.00 20.90 ? 468 PHE A N 1 ATOM 3700 C CA . PHE A 1 468 ? -13.624 19.311 3.660 1.00 20.06 ? 468 PHE A CA 1 ATOM 3701 C C . PHE A 1 468 ? -13.885 18.071 2.786 1.00 19.30 ? 468 PHE A C 1 ATOM 3702 O O . PHE A 1 468 ? -13.440 18.007 1.639 1.00 19.64 ? 468 PHE A O 1 ATOM 3703 C CB . PHE A 1 468 ? -14.528 20.430 3.182 1.00 19.70 ? 468 PHE A CB 1 ATOM 3704 C CG . PHE A 1 468 ? -15.992 20.074 3.247 1.00 19.93 ? 468 PHE A CG 1 ATOM 3705 C CD1 . PHE A 1 468 ? -16.654 20.084 4.469 1.00 22.11 ? 468 PHE A CD1 1 ATOM 3706 C CD2 . PHE A 1 468 ? -16.677 19.653 2.092 1.00 19.22 ? 468 PHE A CD2 1 ATOM 3707 C CE1 . PHE A 1 468 ? -18.015 19.748 4.553 1.00 21.54 ? 468 PHE A CE1 1 ATOM 3708 C CE2 . PHE A 1 468 ? -18.048 19.293 2.153 1.00 19.73 ? 468 PHE A CE2 1 ATOM 3709 C CZ . PHE A 1 468 ? -18.700 19.341 3.375 1.00 20.45 ? 468 PHE A CZ 1 ATOM 3710 N N . THR A 1 469 ? -14.559 17.072 3.348 1.00 19.06 ? 469 THR A N 1 ATOM 3711 C CA . THR A 1 469 ? -14.917 15.869 2.609 1.00 18.78 ? 469 THR A CA 1 ATOM 3712 C C . THR A 1 469 ? -16.454 15.837 2.600 1.00 18.85 ? 469 THR A C 1 ATOM 3713 O O . THR A 1 469 ? -17.063 15.841 3.665 1.00 18.42 ? 469 THR A O 1 ATOM 3714 C CB . THR A 1 469 ? -14.290 14.597 3.273 1.00 20.81 ? 469 THR A CB 1 ATOM 3715 O OG1 . THR A 1 469 ? -12.865 14.797 3.447 1.00 21.33 ? 469 THR A OG1 1 ATOM 3716 C CG2 . THR A 1 469 ? -14.515 13.327 2.414 1.00 20.06 ? 469 THR A CG2 1 ATOM 3717 N N . PRO A 1 470 ? -17.084 15.843 1.395 1.00 18.31 ? 470 PRO A N 1 ATOM 3718 C CA . PRO A 1 470 ? -18.567 15.687 1.343 1.00 19.11 ? 470 PRO A CA 1 ATOM 3719 C C . PRO A 1 470 ? -18.924 14.347 1.996 1.00 19.31 ? 470 PRO A C 1 ATOM 3720 O O . PRO A 1 470 ? -18.045 13.518 2.191 1.00 19.87 ? 470 PRO A O 1 ATOM 3721 C CB . PRO A 1 470 ? -18.878 15.645 -0.171 1.00 17.80 ? 470 PRO A CB 1 ATOM 3722 C CG . PRO A 1 470 ? -17.707 16.243 -0.831 1.00 19.55 ? 470 PRO A CG 1 ATOM 3723 C CD . PRO A 1 470 ? -16.487 15.980 0.053 1.00 18.87 ? 470 PRO A CD 1 ATOM 3724 N N . ARG A 1 471 ? -20.193 14.085 2.298 1.00 19.26 ? 471 ARG A N 1 ATOM 3725 C CA . ARG A 1 471 ? -20.523 12.864 3.018 1.00 19.52 ? 471 ARG A CA 1 ATOM 3726 C C . ARG A 1 471 ? -20.543 11.602 2.149 1.00 19.07 ? 471 ARG A C 1 ATOM 3727 O O . ARG A 1 471 ? -21.505 10.853 2.153 1.00 19.92 ? 471 ARG A O 1 ATOM 3728 C CB . ARG A 1 471 ? -21.847 13.038 3.756 1.00 20.21 ? 471 ARG A CB 1 ATOM 3729 C CG . ARG A 1 471 ? -22.987 13.417 2.852 1.00 23.92 ? 471 ARG A CG 1 ATOM 3730 C CD . ARG A 1 471 ? -24.231 13.561 3.645 1.00 28.80 ? 471 ARG A CD 1 ATOM 3731 N NE . ARG A 1 471 ? -24.068 14.627 4.630 1.00 31.92 ? 471 ARG A NE 1 ATOM 3732 C CZ . ARG A 1 471 ? -24.992 14.931 5.536 1.00 35.84 ? 471 ARG A CZ 1 ATOM 3733 N NH1 . ARG A 1 471 ? -26.143 14.241 5.575 1.00 35.46 ? 471 ARG A NH1 1 ATOM 3734 N NH2 . ARG A 1 471 ? -24.766 15.924 6.397 1.00 34.00 ? 471 ARG A NH2 1 ATOM 3735 N N . ILE A 1 472 ? -19.442 11.331 1.457 1.00 19.14 ? 472 ILE A N 1 ATOM 3736 C CA . ILE A 1 472 ? -19.331 10.152 0.635 1.00 17.70 ? 472 ILE A CA 1 ATOM 3737 C C . ILE A 1 472 ? -19.261 8.904 1.519 1.00 18.09 ? 472 ILE A C 1 ATOM 3738 O O . ILE A 1 472 ? -18.845 8.977 2.681 1.00 19.50 ? 472 ILE A O 1 ATOM 3739 C CB . ILE A 1 472 ? -18.114 10.222 -0.305 1.00 16.90 ? 472 ILE A CB 1 ATOM 3740 C CG1 . ILE A 1 472 ? -16.805 10.412 0.468 1.00 18.84 ? 472 ILE A CG1 1 ATOM 3741 C CG2 . ILE A 1 472 ? -18.301 11.307 -1.333 1.00 17.97 ? 472 ILE A CG2 1 ATOM 3742 C CD1 . ILE A 1 472 ? -15.622 10.222 -0.393 1.00 20.37 ? 472 ILE A CD1 1 ATOM 3743 N N . LEU A 1 473 ? -19.626 7.763 0.953 1.00 17.86 ? 473 LEU A N 1 ATOM 3744 C CA . LEU A 1 473 ? -19.597 6.518 1.670 1.00 18.84 ? 473 LEU A CA 1 ATOM 3745 C C . LEU A 1 473 ? -18.173 6.284 2.188 1.00 19.14 ? 473 LEU A C 1 ATOM 3746 O O . LEU A 1 473 ? -17.228 6.407 1.429 1.00 20.01 ? 473 LEU A O 1 ATOM 3747 C CB . LEU A 1 473 ? -20.055 5.404 0.739 1.00 18.47 ? 473 LEU A CB 1 ATOM 3748 C CG . LEU A 1 473 ? -20.105 3.981 1.314 1.00 19.04 ? 473 LEU A CG 1 ATOM 3749 C CD1 . LEU A 1 473 ? -20.937 3.799 2.565 1.00 20.60 ? 473 LEU A CD1 1 ATOM 3750 C CD2 . LEU A 1 473 ? -20.520 3.043 0.237 1.00 17.81 ? 473 LEU A CD2 1 ATOM 3751 N N . ASP A 1 474 ? -18.041 6.035 3.494 1.00 20.71 ? 474 ASP A N 1 ATOM 3752 C CA . ASP A 1 474 ? -16.771 5.715 4.140 1.00 21.96 ? 474 ASP A CA 1 ATOM 3753 C C . ASP A 1 474 ? -15.927 6.934 4.486 1.00 21.73 ? 474 ASP A C 1 ATOM 3754 O O . ASP A 1 474 ? -14.976 6.825 5.260 1.00 22.36 ? 474 ASP A O 1 ATOM 3755 C CB . ASP A 1 474 ? -15.923 4.760 3.290 1.00 22.44 ? 474 ASP A CB 1 ATOM 3756 C CG . ASP A 1 474 ? -16.497 3.356 3.213 1.00 26.56 ? 474 ASP A CG 1 ATOM 3757 O OD1 . ASP A 1 474 ? -17.090 2.839 4.204 1.00 31.85 ? 474 ASP A OD1 1 ATOM 3758 O OD2 . ASP A 1 474 ? -16.348 2.739 2.139 1.00 29.74 ? 474 ASP A OD2 1 ATOM 3759 N N . GLY A 1 475 ? -16.241 8.081 3.903 1.00 20.12 ? 475 GLY A N 1 ATOM 3760 C CA . GLY A 1 475 ? -15.650 9.337 4.324 1.00 20.10 ? 475 GLY A CA 1 ATOM 3761 C C . GLY A 1 475 ? -14.220 9.615 3.880 1.00 19.72 ? 475 GLY A C 1 ATOM 3762 O O . GLY A 1 475 ? -13.626 10.549 4.374 1.00 20.91 ? 475 GLY A O 1 ATOM 3763 N N . TYR A 1 476 ? -13.666 8.827 2.963 1.00 19.11 ? 476 TYR A N 1 ATOM 3764 C CA . TYR A 1 476 ? -12.397 9.165 2.355 1.00 19.85 ? 476 TYR A CA 1 ATOM 3765 C C . TYR A 1 476 ? -12.521 8.998 0.867 1.00 19.38 ? 476 TYR A C 1 ATOM 3766 O O . TYR A 1 476 ? -13.117 8.019 0.393 1.00 17.29 ? 476 TYR A O 1 ATOM 3767 C CB . TYR A 1 476 ? -11.252 8.258 2.840 1.00 22.02 ? 476 TYR A CB 1 ATOM 3768 C CG . TYR A 1 476 ? -10.961 8.361 4.322 1.00 23.92 ? 476 TYR A CG 1 ATOM 3769 C CD1 . TYR A 1 476 ? -9.810 9.028 4.794 1.00 25.53 ? 476 TYR A CD1 1 ATOM 3770 C CD2 . TYR A 1 476 ? -11.810 7.770 5.253 1.00 25.68 ? 476 TYR A CD2 1 ATOM 3771 C CE1 . TYR A 1 476 ? -9.556 9.108 6.165 1.00 25.65 ? 476 TYR A CE1 1 ATOM 3772 C CE2 . TYR A 1 476 ? -11.566 7.852 6.617 1.00 26.29 ? 476 TYR A CE2 1 ATOM 3773 C CZ . TYR A 1 476 ? -10.452 8.509 7.062 1.00 25.96 ? 476 TYR A CZ 1 ATOM 3774 O OH . TYR A 1 476 ? -10.235 8.582 8.422 1.00 27.54 ? 476 TYR A OH 1 ATOM 3775 N N . LEU A 1 477 ? -11.896 9.923 0.134 1.00 19.68 ? 477 LEU A N 1 ATOM 3776 C CA . LEU A 1 477 ? -12.036 9.987 -1.335 1.00 19.73 ? 477 LEU A CA 1 ATOM 3777 C C . LEU A 1 477 ? -11.457 8.763 -2.003 1.00 19.63 ? 477 LEU A C 1 ATOM 3778 O O . LEU A 1 477 ? -12.016 8.231 -2.981 1.00 18.19 ? 477 LEU A O 1 ATOM 3779 C CB . LEU A 1 477 ? -11.355 11.248 -1.868 1.00 19.61 ? 477 LEU A CB 1 ATOM 3780 C CG . LEU A 1 477 ? -12.027 12.579 -1.520 1.00 21.79 ? 477 LEU A CG 1 ATOM 3781 C CD1 . LEU A 1 477 ? -11.128 13.730 -2.004 1.00 20.56 ? 477 LEU A CD1 1 ATOM 3782 C CD2 . LEU A 1 477 ? -13.387 12.686 -2.163 1.00 20.46 ? 477 LEU A CD2 1 ATOM 3783 N N . PHE A 1 478 ? -10.374 8.251 -1.426 1.00 18.51 ? 478 PHE A N 1 ATOM 3784 C CA . PHE A 1 478 ? -9.631 7.204 -2.105 1.00 19.16 ? 478 PHE A CA 1 ATOM 3785 C C . PHE A 1 478 ? -10.153 5.835 -1.763 1.00 20.09 ? 478 PHE A C 1 ATOM 3786 O O . PHE A 1 478 ? -9.611 4.853 -2.230 1.00 19.66 ? 478 PHE A O 1 ATOM 3787 C CB . PHE A 1 478 ? -8.164 7.284 -1.733 1.00 19.69 ? 478 PHE A CB 1 ATOM 3788 C CG . PHE A 1 478 ? -7.944 7.383 -0.255 1.00 19.56 ? 478 PHE A CG 1 ATOM 3789 C CD1 . PHE A 1 478 ? -7.990 6.249 0.542 1.00 23.36 ? 478 PHE A CD1 1 ATOM 3790 C CD2 . PHE A 1 478 ? -7.684 8.611 0.343 1.00 19.58 ? 478 PHE A CD2 1 ATOM 3791 C CE1 . PHE A 1 478 ? -7.812 6.338 1.927 1.00 19.37 ? 478 PHE A CE1 1 ATOM 3792 C CE2 . PHE A 1 478 ? -7.491 8.700 1.735 1.00 17.11 ? 478 PHE A CE2 1 ATOM 3793 C CZ . PHE A 1 478 ? -7.553 7.556 2.509 1.00 16.26 ? 478 PHE A CZ 1 ATOM 3794 N N . CYS A 1 479 ? -11.217 5.754 -0.951 1.00 21.29 ? 479 CYS A N 1 ATOM 3795 C CA A CYS A 1 479 ? -11.773 4.454 -0.595 0.50 21.24 ? 479 CYS A CA 1 ATOM 3796 C CA B CYS A 1 479 ? -11.820 4.488 -0.580 0.50 21.73 ? 479 CYS A CA 1 ATOM 3797 C C . CYS A 1 479 ? -12.309 3.712 -1.813 1.00 21.48 ? 479 CYS A C 1 ATOM 3798 O O . CYS A 1 479 ? -13.115 4.245 -2.594 1.00 21.14 ? 479 CYS A O 1 ATOM 3799 C CB A CYS A 1 479 ? -12.866 4.580 0.470 0.50 21.63 ? 479 CYS A CB 1 ATOM 3800 C CB B CYS A 1 479 ? -13.005 4.761 0.353 0.50 22.18 ? 479 CYS A CB 1 ATOM 3801 S SG A CYS A 1 479 ? -12.180 4.782 2.110 0.50 23.14 ? 479 CYS A SG 1 ATOM 3802 S SG B CYS A 1 479 ? -13.788 3.308 0.957 0.50 26.42 ? 479 CYS A SG 1 ATOM 3803 N N . LYS A 1 480 ? -11.846 2.472 -1.956 1.00 20.96 ? 480 LYS A N 1 ATOM 3804 C CA . LYS A 1 480 ? -12.196 1.594 -3.088 1.00 21.48 ? 480 LYS A CA 1 ATOM 3805 C C . LYS A 1 480 ? -11.956 2.242 -4.462 1.00 20.59 ? 480 LYS A C 1 ATOM 3806 O O . LYS A 1 480 ? -12.656 1.929 -5.439 1.00 19.77 ? 480 LYS A O 1 ATOM 3807 C CB . LYS A 1 480 ? -13.640 1.042 -2.965 1.00 23.77 ? 480 LYS A CB 1 ATOM 3808 C CG . LYS A 1 480 ? -13.899 0.046 -1.786 1.00 26.38 ? 480 LYS A CG 1 ATOM 3809 C CD . LYS A 1 480 ? -12.736 -0.930 -1.521 1.00 30.75 ? 480 LYS A CD 1 ATOM 3810 C CE . LYS A 1 480 ? -13.012 -1.768 -0.254 1.00 32.84 ? 480 LYS A CE 1 ATOM 3811 N NZ . LYS A 1 480 ? -11.767 -1.960 0.579 1.00 38.53 ? 480 LYS A NZ 1 ATOM 3812 N N . THR A 1 481 ? -10.963 3.128 -4.548 1.00 18.55 ? 481 THR A N 1 ATOM 3813 C CA . THR A 1 481 ? -10.596 3.740 -5.845 1.00 18.25 ? 481 THR A CA 1 ATOM 3814 C C . THR A 1 481 ? -9.115 4.075 -5.873 1.00 18.52 ? 481 THR A C 1 ATOM 3815 O O . THR A 1 481 ? -8.393 3.520 -5.077 1.00 18.16 ? 481 THR A O 1 ATOM 3816 C CB . THR A 1 481 ? -11.500 4.950 -6.283 1.00 18.90 ? 481 THR A CB 1 ATOM 3817 O OG1 . THR A 1 481 ? -11.131 5.330 -7.618 1.00 18.94 ? 481 THR A OG1 1 ATOM 3818 C CG2 . THR A 1 481 ? -11.341 6.149 -5.355 1.00 18.06 ? 481 THR A CG2 1 ATOM 3819 N N . LEU A 1 482 ? -8.674 4.968 -6.772 1.00 18.52 ? 482 LEU A N 1 ATOM 3820 C CA . LEU A 1 482 ? -7.250 5.351 -6.888 1.00 19.76 ? 482 LEU A CA 1 ATOM 3821 C C . LEU A 1 482 ? -6.930 6.513 -5.944 1.00 19.49 ? 482 LEU A C 1 ATOM 3822 O O . LEU A 1 482 ? -7.845 7.262 -5.530 1.00 19.21 ? 482 LEU A O 1 ATOM 3823 C CB . LEU A 1 482 ? -6.908 5.713 -8.338 1.00 18.70 ? 482 LEU A CB 1 ATOM 3824 C CG . LEU A 1 482 ? -7.401 4.724 -9.396 1.00 21.10 ? 482 LEU A CG 1 ATOM 3825 C CD1 . LEU A 1 482 ? -6.986 5.145 -10.785 1.00 22.69 ? 482 LEU A CD1 1 ATOM 3826 C CD2 . LEU A 1 482 ? -6.927 3.292 -9.089 1.00 22.79 ? 482 LEU A CD2 1 ATOM 3827 N N . CYS A 1 483 ? -5.662 6.601 -5.518 1.00 19.79 ? 483 CYS A N 1 ATOM 3828 C CA . CYS A 1 483 ? -5.146 7.792 -4.891 1.00 20.32 ? 483 CYS A CA 1 ATOM 3829 C C . CYS A 1 483 ? -5.594 9.049 -5.645 1.00 20.03 ? 483 CYS A C 1 ATOM 3830 O O . CYS A 1 483 ? -5.574 9.085 -6.891 1.00 20.40 ? 483 CYS A O 1 ATOM 3831 C CB . CYS A 1 483 ? -3.604 7.762 -4.939 1.00 21.79 ? 483 CYS A CB 1 ATOM 3832 S SG . CYS A 1 483 ? -2.982 6.344 -4.015 1.00 31.41 ? 483 CYS A SG 1 ATOM 3833 N N . MET A 1 484 ? -5.990 10.074 -4.888 1.00 19.50 ? 484 MET A N 1 ATOM 3834 C CA . MET A 1 484 ? -6.434 11.365 -5.451 1.00 19.08 ? 484 MET A CA 1 ATOM 3835 C C . MET A 1 484 ? -5.272 12.148 -6.064 1.00 19.05 ? 484 MET A C 1 ATOM 3836 O O . MET A 1 484 ? -5.492 13.075 -6.837 1.00 19.84 ? 484 MET A O 1 ATOM 3837 C CB . MET A 1 484 ? -7.110 12.205 -4.383 1.00 17.98 ? 484 MET A CB 1 ATOM 3838 C CG . MET A 1 484 ? -8.452 11.655 -3.894 1.00 19.07 ? 484 MET A CG 1 ATOM 3839 S SD . MET A 1 484 ? -9.604 11.602 -5.309 1.00 19.89 ? 484 MET A SD 1 ATOM 3840 C CE . MET A 1 484 ? -9.784 9.871 -5.593 1.00 16.76 ? 484 MET A CE 1 ATOM 3841 N N . ASP A 1 485 ? -4.040 11.806 -5.690 1.00 20.24 ? 485 ASP A N 1 ATOM 3842 C CA . ASP A 1 485 ? -2.867 12.435 -6.304 1.00 20.74 ? 485 ASP A CA 1 ATOM 3843 C C . ASP A 1 485 ? -2.267 11.648 -7.484 1.00 21.06 ? 485 ASP A C 1 ATOM 3844 O O . ASP A 1 485 ? -1.224 12.027 -8.034 1.00 21.96 ? 485 ASP A O 1 ATOM 3845 C CB . ASP A 1 485 ? -1.810 12.843 -5.246 1.00 21.86 ? 485 ASP A CB 1 ATOM 3846 C CG . ASP A 1 485 ? -1.286 11.666 -4.409 1.00 23.35 ? 485 ASP A CG 1 ATOM 3847 O OD1 . ASP A 1 485 ? -1.737 10.504 -4.592 1.00 23.33 ? 485 ASP A OD1 1 ATOM 3848 O OD2 . ASP A 1 485 ? -0.415 11.922 -3.534 1.00 25.90 ? 485 ASP A OD2 1 ATOM 3849 N N . ALA A 1 486 ? -2.965 10.600 -7.909 1.00 20.50 ? 486 ALA A N 1 ATOM 3850 C CA . ALA A 1 486 ? -2.635 9.893 -9.134 1.00 20.22 ? 486 ALA A CA 1 ATOM 3851 C C . ALA A 1 486 ? -2.813 10.857 -10.307 1.00 21.04 ? 486 ALA A C 1 ATOM 3852 O O . ALA A 1 486 ? -3.575 11.841 -10.231 1.00 20.02 ? 486 ALA A O 1 ATOM 3853 C CB . ALA A 1 486 ? -3.505 8.623 -9.299 1.00 20.53 ? 486 ALA A CB 1 ATOM 3854 N N . VAL A 1 487 ? -2.087 10.567 -11.376 1.00 20.53 ? 487 VAL A N 1 ATOM 3855 C CA . VAL A 1 487 ? -1.807 11.508 -12.441 1.00 22.01 ? 487 VAL A CA 1 ATOM 3856 C C . VAL A 1 487 ? -2.235 10.913 -13.778 1.00 21.43 ? 487 VAL A C 1 ATOM 3857 O O . VAL A 1 487 ? -1.843 9.797 -14.130 1.00 21.03 ? 487 VAL A O 1 ATOM 3858 C CB . VAL A 1 487 ? -0.259 11.823 -12.418 1.00 22.42 ? 487 VAL A CB 1 ATOM 3859 C CG1 . VAL A 1 487 ? 0.260 12.257 -13.751 1.00 24.88 ? 487 VAL A CG1 1 ATOM 3860 C CG2 . VAL A 1 487 ? 0.008 12.905 -11.370 1.00 24.20 ? 487 VAL A CG2 1 ATOM 3861 N N . GLN A 1 488 ? -3.069 11.664 -14.503 1.00 20.90 ? 488 GLN A N 1 ATOM 3862 C CA . GLN A 1 488 ? -3.523 11.295 -15.831 1.00 20.17 ? 488 GLN A CA 1 ATOM 3863 C C . GLN A 1 488 ? -3.315 12.458 -16.800 1.00 20.53 ? 488 GLN A C 1 ATOM 3864 O O . GLN A 1 488 ? -3.031 13.587 -16.391 1.00 20.97 ? 488 GLN A O 1 ATOM 3865 C CB . GLN A 1 488 ? -5.005 10.943 -15.765 1.00 20.30 ? 488 GLN A CB 1 ATOM 3866 C CG . GLN A 1 488 ? -5.236 9.566 -15.163 1.00 21.20 ? 488 GLN A CG 1 ATOM 3867 C CD . GLN A 1 488 ? -6.707 9.178 -15.081 1.00 24.66 ? 488 GLN A CD 1 ATOM 3868 O OE1 . GLN A 1 488 ? -7.302 8.714 -16.054 1.00 29.10 ? 488 GLN A OE1 1 ATOM 3869 N NE2 . GLN A 1 488 ? -7.276 9.325 -13.912 1.00 24.78 ? 488 GLN A NE2 1 ATOM 3870 N N . HIS A 1 489 ? -3.434 12.186 -18.090 1.00 21.24 ? 489 HIS A N 1 ATOM 3871 C CA . HIS A 1 489 ? -3.328 13.256 -19.116 1.00 22.01 ? 489 HIS A CA 1 ATOM 3872 C C . HIS A 1 489 ? -4.203 14.512 -18.814 1.00 22.03 ? 489 HIS A C 1 ATOM 3873 O O . HIS A 1 489 ? -3.700 15.620 -18.856 1.00 21.84 ? 489 HIS A O 1 ATOM 3874 C CB . HIS A 1 489 ? -3.574 12.679 -20.520 1.00 22.98 ? 489 HIS A CB 1 ATOM 3875 C CG . HIS A 1 489 ? -3.465 13.693 -21.604 1.00 26.03 ? 489 HIS A CG 1 ATOM 3876 N ND1 . HIS A 1 489 ? -4.547 14.094 -22.361 1.00 29.09 ? 489 HIS A ND1 1 ATOM 3877 C CD2 . HIS A 1 489 ? -2.408 14.428 -22.030 1.00 28.97 ? 489 HIS A CD2 1 ATOM 3878 C CE1 . HIS A 1 489 ? -4.160 15.024 -23.218 1.00 28.82 ? 489 HIS A CE1 1 ATOM 3879 N NE2 . HIS A 1 489 ? -2.869 15.248 -23.034 1.00 30.73 ? 489 HIS A NE2 1 ATOM 3880 N N . TRP A 1 490 ? -5.487 14.355 -18.446 1.00 21.67 ? 490 TRP A N 1 ATOM 3881 C CA . TRP A 1 490 ? -6.295 15.519 -18.105 1.00 21.51 ? 490 TRP A CA 1 ATOM 3882 C C . TRP A 1 490 ? -6.045 16.163 -16.748 1.00 21.93 ? 490 TRP A C 1 ATOM 3883 O O . TRP A 1 490 ? -6.573 17.236 -16.493 1.00 22.64 ? 490 TRP A O 1 ATOM 3884 C CB . TRP A 1 490 ? -7.804 15.206 -18.146 1.00 20.45 ? 490 TRP A CB 1 ATOM 3885 C CG . TRP A 1 490 ? -8.380 14.960 -19.489 1.00 21.56 ? 490 TRP A CG 1 ATOM 3886 C CD1 . TRP A 1 490 ? -7.796 15.203 -20.707 1.00 22.18 ? 490 TRP A CD1 1 ATOM 3887 C CD2 . TRP A 1 490 ? -9.701 14.467 -19.768 1.00 21.78 ? 490 TRP A CD2 1 ATOM 3888 N NE1 . TRP A 1 490 ? -8.644 14.831 -21.717 1.00 21.62 ? 490 TRP A NE1 1 ATOM 3889 C CE2 . TRP A 1 490 ? -9.819 14.368 -21.170 1.00 23.29 ? 490 TRP A CE2 1 ATOM 3890 C CE3 . TRP A 1 490 ? -10.766 14.030 -18.962 1.00 23.40 ? 490 TRP A CE3 1 ATOM 3891 C CZ2 . TRP A 1 490 ? -10.983 13.913 -21.794 1.00 22.27 ? 490 TRP A CZ2 1 ATOM 3892 C CZ3 . TRP A 1 490 ? -11.927 13.569 -19.588 1.00 22.66 ? 490 TRP A CZ3 1 ATOM 3893 C CH2 . TRP A 1 490 ? -12.015 13.506 -20.987 1.00 22.19 ? 490 TRP A CH2 1 ATOM 3894 N N . GLY A 1 491 ? -5.347 15.492 -15.838 1.00 21.56 ? 491 GLY A N 1 ATOM 3895 C CA . GLY A 1 491 ? -5.028 16.100 -14.552 1.00 21.22 ? 491 GLY A CA 1 ATOM 3896 C C . GLY A 1 491 ? -4.912 15.072 -13.456 1.00 21.38 ? 491 GLY A C 1 ATOM 3897 O O . GLY A 1 491 ? -4.740 13.891 -13.723 1.00 22.08 ? 491 GLY A O 1 ATOM 3898 N N . LYS A 1 492 ? -5.021 15.516 -12.212 1.00 21.92 ? 492 LYS A N 1 ATOM 3899 C CA . LYS A 1 492 ? -4.887 14.613 -11.091 1.00 22.48 ? 492 LYS A CA 1 ATOM 3900 C C . LYS A 1 492 ? -6.227 13.952 -10.805 1.00 21.16 ? 492 LYS A C 1 ATOM 3901 O O . LYS A 1 492 ? -7.294 14.526 -11.098 1.00 20.41 ? 492 LYS A O 1 ATOM 3902 C CB . LYS A 1 492 ? -4.294 15.350 -9.874 1.00 23.03 ? 492 LYS A CB 1 ATOM 3903 C CG . LYS A 1 492 ? -2.769 15.588 -10.054 1.00 25.20 ? 492 LYS A CG 1 ATOM 3904 C CD . LYS A 1 492 ? -2.056 16.140 -8.807 1.00 26.22 ? 492 LYS A CD 1 ATOM 3905 C CE . LYS A 1 492 ? -0.476 15.967 -8.892 1.00 29.99 ? 492 LYS A CE 1 ATOM 3906 N NZ . LYS A 1 492 ? 0.030 14.706 -8.149 1.00 30.13 ? 492 LYS A NZ 1 ATOM 3907 N N . GLN A 1 493 ? -6.179 12.750 -10.242 1.00 19.38 ? 493 GLN A N 1 ATOM 3908 C CA . GLN A 1 493 ? -7.410 12.023 -9.921 1.00 20.40 ? 493 GLN A CA 1 ATOM 3909 C C . GLN A 1 493 ? -8.413 12.862 -9.100 1.00 19.43 ? 493 GLN A C 1 ATOM 3910 O O . GLN A 1 493 ? -9.624 12.744 -9.293 1.00 20.08 ? 493 GLN A O 1 ATOM 3911 C CB . GLN A 1 493 ? -7.002 10.708 -9.256 1.00 21.38 ? 493 GLN A CB 1 ATOM 3912 C CG . GLN A 1 493 ? -8.083 9.795 -8.805 1.00 23.56 ? 493 GLN A CG 1 ATOM 3913 C CD . GLN A 1 493 ? -8.761 9.020 -9.930 1.00 25.92 ? 493 GLN A CD 1 ATOM 3914 O OE1 . GLN A 1 493 ? -8.346 9.038 -11.100 1.00 25.29 ? 493 GLN A OE1 1 ATOM 3915 N NE2 . GLN A 1 493 ? -9.815 8.322 -9.559 1.00 24.28 ? 493 GLN A NE2 1 ATOM 3916 N N . TYR A 1 494 ? -7.918 13.701 -8.190 1.00 17.75 ? 494 TYR A N 1 ATOM 3917 C CA . TYR A 1 494 ? -8.762 14.603 -7.388 1.00 18.75 ? 494 TYR A CA 1 ATOM 3918 C C . TYR A 1 494 ? -9.802 15.326 -8.251 1.00 19.64 ? 494 TYR A C 1 ATOM 3919 O O . TYR A 1 494 ? -10.971 15.494 -7.856 1.00 19.40 ? 494 TYR A O 1 ATOM 3920 C CB . TYR A 1 494 ? -7.875 15.649 -6.706 1.00 17.20 ? 494 TYR A CB 1 ATOM 3921 C CG . TYR A 1 494 ? -8.563 16.536 -5.711 1.00 15.87 ? 494 TYR A CG 1 ATOM 3922 C CD1 . TYR A 1 494 ? -8.789 16.098 -4.396 1.00 15.01 ? 494 TYR A CD1 1 ATOM 3923 C CD2 . TYR A 1 494 ? -9.026 17.797 -6.079 1.00 17.29 ? 494 TYR A CD2 1 ATOM 3924 C CE1 . TYR A 1 494 ? -9.403 16.916 -3.453 1.00 15.43 ? 494 TYR A CE1 1 ATOM 3925 C CE2 . TYR A 1 494 ? -9.644 18.608 -5.166 1.00 17.42 ? 494 TYR A CE2 1 ATOM 3926 C CZ . TYR A 1 494 ? -9.843 18.159 -3.847 1.00 18.32 ? 494 TYR A CZ 1 ATOM 3927 O OH . TYR A 1 494 ? -10.414 19.001 -2.923 1.00 16.13 ? 494 TYR A OH 1 ATOM 3928 N N . ASP A 1 495 ? -9.339 15.776 -9.416 1.00 19.67 ? 495 ASP A N 1 ATOM 3929 C CA . ASP A 1 495 ? -10.145 16.575 -10.337 1.00 19.93 ? 495 ASP A CA 1 ATOM 3930 C C . ASP A 1 495 ? -10.913 15.720 -11.344 1.00 20.73 ? 495 ASP A C 1 ATOM 3931 O O . ASP A 1 495 ? -12.029 16.090 -11.733 1.00 21.53 ? 495 ASP A O 1 ATOM 3932 C CB . ASP A 1 495 ? -9.239 17.557 -11.101 1.00 20.02 ? 495 ASP A CB 1 ATOM 3933 C CG . ASP A 1 495 ? -8.731 18.705 -10.236 1.00 22.31 ? 495 ASP A CG 1 ATOM 3934 O OD1 . ASP A 1 495 ? -9.490 19.227 -9.352 1.00 23.81 ? 495 ASP A OD1 1 ATOM 3935 O OD2 . ASP A 1 495 ? -7.539 19.096 -10.454 1.00 22.42 ? 495 ASP A OD2 1 ATOM 3936 N N . ILE A 1 496 ? -10.325 14.594 -11.770 1.00 19.48 ? 496 ILE A N 1 ATOM 3937 C CA . ILE A 1 496 ? -10.883 13.838 -12.901 1.00 20.01 ? 496 ILE A CA 1 ATOM 3938 C C . ILE A 1 496 ? -11.509 12.501 -12.543 1.00 18.18 ? 496 ILE A C 1 ATOM 3939 O O . ILE A 1 496 ? -12.001 11.784 -13.428 1.00 19.43 ? 496 ILE A O 1 ATOM 3940 C CB . ILE A 1 496 ? -9.881 13.690 -14.070 1.00 21.21 ? 496 ILE A CB 1 ATOM 3941 C CG1 . ILE A 1 496 ? -8.667 12.918 -13.625 1.00 22.67 ? 496 ILE A CG1 1 ATOM 3942 C CG2 . ILE A 1 496 ? -9.438 15.052 -14.613 1.00 20.95 ? 496 ILE A CG2 1 ATOM 3943 C CD1 . ILE A 1 496 ? -7.991 12.301 -14.765 1.00 26.82 ? 496 ILE A CD1 1 ATOM 3944 N N . HIS A 1 497 ? -11.540 12.176 -11.249 1.00 17.62 ? 497 HIS A N 1 ATOM 3945 C CA . HIS A 1 497 ? -12.055 10.883 -10.789 1.00 16.24 ? 497 HIS A CA 1 ATOM 3946 C C . HIS A 1 497 ? -13.478 10.633 -11.356 1.00 15.83 ? 497 HIS A C 1 ATOM 3947 O O . HIS A 1 497 ? -13.755 9.547 -11.860 1.00 15.85 ? 497 HIS A O 1 ATOM 3948 C CB . HIS A 1 497 ? -12.118 10.849 -9.273 1.00 15.97 ? 497 HIS A CB 1 ATOM 3949 C CG . HIS A 1 497 ? -12.786 9.633 -8.727 1.00 16.52 ? 497 HIS A CG 1 ATOM 3950 N ND1 . HIS A 1 497 ? -14.154 9.566 -8.504 1.00 17.45 ? 497 HIS A ND1 1 ATOM 3951 C CD2 . HIS A 1 497 ? -12.289 8.427 -8.387 1.00 13.37 ? 497 HIS A CD2 1 ATOM 3952 C CE1 . HIS A 1 497 ? -14.451 8.387 -7.996 1.00 13.57 ? 497 HIS A CE1 1 ATOM 3953 N NE2 . HIS A 1 497 ? -13.341 7.674 -7.927 1.00 21.43 ? 497 HIS A NE2 1 ATOM 3954 N N . ASN A 1 498 ? -14.349 11.634 -11.281 1.00 16.30 ? 498 ASN A N 1 ATOM 3955 C CA . ASN A 1 498 ? -15.730 11.449 -11.780 1.00 16.47 ? 498 ASN A CA 1 ATOM 3956 C C . ASN A 1 498 ? -15.799 11.331 -13.300 1.00 17.19 ? 498 ASN A C 1 ATOM 3957 O O . ASN A 1 498 ? -16.853 11.122 -13.867 1.00 16.50 ? 498 ASN A O 1 ATOM 3958 C CB . ASN A 1 498 ? -16.616 12.610 -11.307 1.00 16.10 ? 498 ASN A CB 1 ATOM 3959 C CG . ASN A 1 498 ? -17.037 12.486 -9.860 1.00 17.62 ? 498 ASN A CG 1 ATOM 3960 O OD1 . ASN A 1 498 ? -17.631 13.411 -9.267 1.00 22.45 ? 498 ASN A OD1 1 ATOM 3961 N ND2 . ASN A 1 498 ? -16.775 11.367 -9.289 1.00 16.65 ? 498 ASN A ND2 1 ATOM 3962 N N . LEU A 1 499 ? -14.673 11.527 -13.971 1.00 15.77 ? 499 LEU A N 1 ATOM 3963 C CA . LEU A 1 499 ? -14.599 11.433 -15.423 1.00 17.02 ? 499 LEU A CA 1 ATOM 3964 C C . LEU A 1 499 ? -13.995 10.149 -15.954 1.00 17.61 ? 499 LEU A C 1 ATOM 3965 O O . LEU A 1 499 ? -13.801 10.011 -17.160 1.00 17.35 ? 499 LEU A O 1 ATOM 3966 C CB . LEU A 1 499 ? -13.825 12.636 -16.011 1.00 16.49 ? 499 LEU A CB 1 ATOM 3967 C CG . LEU A 1 499 ? -14.305 14.055 -15.632 1.00 17.14 ? 499 LEU A CG 1 ATOM 3968 C CD1 . LEU A 1 499 ? -13.432 15.166 -16.217 1.00 16.41 ? 499 LEU A CD1 1 ATOM 3969 C CD2 . LEU A 1 499 ? -15.795 14.257 -16.063 1.00 16.16 ? 499 LEU A CD2 1 ATOM 3970 N N . TYR A 1 500 ? -13.635 9.219 -15.072 1.00 17.69 ? 500 TYR A N 1 ATOM 3971 C CA . TYR A 1 500 ? -12.988 7.997 -15.558 1.00 17.44 ? 500 TYR A CA 1 ATOM 3972 C C . TYR A 1 500 ? -13.910 7.145 -16.410 1.00 17.14 ? 500 TYR A C 1 ATOM 3973 O O . TYR A 1 500 ? -13.524 6.702 -17.492 1.00 18.62 ? 500 TYR A O 1 ATOM 3974 C CB . TYR A 1 500 ? -12.405 7.166 -14.402 1.00 17.83 ? 500 TYR A CB 1 ATOM 3975 C CG . TYR A 1 500 ? -11.468 6.079 -14.861 1.00 16.52 ? 500 TYR A CG 1 ATOM 3976 C CD1 . TYR A 1 500 ? -10.105 6.266 -14.822 1.00 17.55 ? 500 TYR A CD1 1 ATOM 3977 C CD2 . TYR A 1 500 ? -11.943 4.864 -15.333 1.00 15.13 ? 500 TYR A CD2 1 ATOM 3978 C CE1 . TYR A 1 500 ? -9.243 5.288 -15.259 1.00 16.81 ? 500 TYR A CE1 1 ATOM 3979 C CE2 . TYR A 1 500 ? -11.087 3.865 -15.773 1.00 16.14 ? 500 TYR A CE2 1 ATOM 3980 C CZ . TYR A 1 500 ? -9.715 4.105 -15.723 1.00 17.82 ? 500 TYR A CZ 1 ATOM 3981 O OH . TYR A 1 500 ? -8.821 3.167 -16.125 1.00 19.77 ? 500 TYR A OH 1 ATOM 3982 N N . GLY A 1 501 ? -15.127 6.890 -15.938 1.00 17.61 ? 501 GLY A N 1 ATOM 3983 C CA . GLY A 1 501 ? -16.006 6.046 -16.712 1.00 16.91 ? 501 GLY A CA 1 ATOM 3984 C C . GLY A 1 501 ? -16.444 6.750 -17.977 1.00 16.99 ? 501 GLY A C 1 ATOM 3985 O O . GLY A 1 501 ? -16.682 6.116 -18.995 1.00 17.81 ? 501 GLY A O 1 ATOM 3986 N N . TYR A 1 502 ? -16.585 8.063 -17.897 1.00 16.88 ? 502 TYR A N 1 ATOM 3987 C CA . TYR A 1 502 ? -16.910 8.877 -19.083 1.00 16.94 ? 502 TYR A CA 1 ATOM 3988 C C . TYR A 1 502 ? -15.762 8.759 -20.114 1.00 16.60 ? 502 TYR A C 1 ATOM 3989 O O . TYR A 1 502 ? -15.998 8.435 -21.259 1.00 16.24 ? 502 TYR A O 1 ATOM 3990 C CB . TYR A 1 502 ? -17.151 10.310 -18.626 1.00 16.58 ? 502 TYR A CB 1 ATOM 3991 C CG . TYR A 1 502 ? -17.268 11.354 -19.706 1.00 17.12 ? 502 TYR A CG 1 ATOM 3992 C CD1 . TYR A 1 502 ? -18.466 11.548 -20.381 1.00 16.51 ? 502 TYR A CD1 1 ATOM 3993 C CD2 . TYR A 1 502 ? -16.174 12.191 -20.029 1.00 18.17 ? 502 TYR A CD2 1 ATOM 3994 C CE1 . TYR A 1 502 ? -18.574 12.504 -21.377 1.00 17.62 ? 502 TYR A CE1 1 ATOM 3995 C CE2 . TYR A 1 502 ? -16.287 13.173 -21.008 1.00 16.99 ? 502 TYR A CE2 1 ATOM 3996 C CZ . TYR A 1 502 ? -17.513 13.325 -21.668 1.00 20.13 ? 502 TYR A CZ 1 ATOM 3997 O OH . TYR A 1 502 ? -17.663 14.283 -22.637 1.00 20.95 ? 502 TYR A OH 1 ATOM 3998 N N . SER A 1 503 ? -14.513 8.948 -19.694 1.00 16.47 ? 503 SER A N 1 ATOM 3999 C CA . SER A 1 503 ? -13.401 8.855 -20.650 1.00 16.53 ? 503 SER A CA 1 ATOM 4000 C C . SER A 1 503 ? -13.290 7.447 -21.239 1.00 17.04 ? 503 SER A C 1 ATOM 4001 O O . SER A 1 503 ? -12.960 7.269 -22.417 1.00 16.57 ? 503 SER A O 1 ATOM 4002 C CB . SER A 1 503 ? -12.095 9.318 -19.980 1.00 16.95 ? 503 SER A CB 1 ATOM 4003 O OG . SER A 1 503 ? -11.784 8.422 -18.933 1.00 15.70 ? 503 SER A OG 1 ATOM 4004 N N . MET A 1 504 ? -13.563 6.426 -20.421 1.00 17.21 ? 504 MET A N 1 ATOM 4005 C CA . MET A 1 504 ? -13.532 5.060 -20.865 1.00 17.43 ? 504 MET A CA 1 ATOM 4006 C C . MET A 1 504 ? -14.638 4.807 -21.924 1.00 16.97 ? 504 MET A C 1 ATOM 4007 O O . MET A 1 504 ? -14.387 4.138 -22.921 1.00 15.24 ? 504 MET A O 1 ATOM 4008 C CB . MET A 1 504 ? -13.674 4.092 -19.678 1.00 17.82 ? 504 MET A CB 1 ATOM 4009 C CG . MET A 1 504 ? -13.513 2.633 -20.084 1.00 18.26 ? 504 MET A CG 1 ATOM 4010 S SD . MET A 1 504 ? -13.763 1.521 -18.694 1.00 18.58 ? 504 MET A SD 1 ATOM 4011 C CE . MET A 1 504 ? -13.398 -0.053 -19.493 1.00 19.15 ? 504 MET A CE 1 ATOM 4012 N N . ALA A 1 505 ? -15.845 5.319 -21.689 1.00 16.66 ? 505 ALA A N 1 ATOM 4013 C CA . ALA A 1 505 ? -16.922 5.178 -22.705 1.00 16.75 ? 505 ALA A CA 1 ATOM 4014 C C . ALA A 1 505 ? -16.526 5.870 -24.019 1.00 17.90 ? 505 ALA A C 1 ATOM 4015 O O . ALA A 1 505 ? -16.731 5.291 -25.102 1.00 18.26 ? 505 ALA A O 1 ATOM 4016 C CB . ALA A 1 505 ? -18.304 5.720 -22.174 1.00 15.85 ? 505 ALA A CB 1 ATOM 4017 N N . VAL A 1 506 ? -15.888 7.043 -23.926 1.00 18.41 ? 506 VAL A N 1 ATOM 4018 C CA . VAL A 1 506 ? -15.462 7.777 -25.133 1.00 19.12 ? 506 VAL A CA 1 ATOM 4019 C C . VAL A 1 506 ? -14.435 6.951 -25.935 1.00 20.14 ? 506 VAL A C 1 ATOM 4020 O O . VAL A 1 506 ? -14.568 6.777 -27.163 1.00 18.67 ? 506 VAL A O 1 ATOM 4021 C CB . VAL A 1 506 ? -14.911 9.205 -24.776 1.00 19.43 ? 506 VAL A CB 1 ATOM 4022 C CG1 . VAL A 1 506 ? -14.196 9.855 -25.972 1.00 20.29 ? 506 VAL A CG1 1 ATOM 4023 C CG2 . VAL A 1 506 ? -16.043 10.125 -24.230 1.00 19.30 ? 506 VAL A CG2 1 ATOM 4024 N N . ALA A 1 507 ? -13.418 6.429 -25.219 1.00 20.22 ? 507 ALA A N 1 ATOM 4025 C CA . ALA A 1 507 ? -12.407 5.522 -25.788 1.00 20.05 ? 507 ALA A CA 1 ATOM 4026 C C . ALA A 1 507 ? -13.006 4.266 -26.361 1.00 19.80 ? 507 ALA A C 1 ATOM 4027 O O . ALA A 1 507 ? -12.539 3.763 -27.366 1.00 20.53 ? 507 ALA A O 1 ATOM 4028 C CB . ALA A 1 507 ? -11.393 5.136 -24.691 1.00 19.95 ? 507 ALA A CB 1 ATOM 4029 N N . THR A 1 508 ? -13.998 3.704 -25.680 1.00 19.81 ? 508 THR A N 1 ATOM 4030 C CA . THR A 1 508 ? -14.624 2.474 -26.135 1.00 19.91 ? 508 THR A CA 1 ATOM 4031 C C . THR A 1 508 ? -15.408 2.726 -27.438 1.00 20.29 ? 508 THR A C 1 ATOM 4032 O O . THR A 1 508 ? -15.329 1.930 -28.378 1.00 19.70 ? 508 THR A O 1 ATOM 4033 C CB . THR A 1 508 ? -15.467 1.816 -25.005 1.00 20.20 ? 508 THR A CB 1 ATOM 4034 O OG1 . THR A 1 508 ? -14.585 1.501 -23.913 1.00 19.72 ? 508 THR A OG1 1 ATOM 4035 C CG2 . THR A 1 508 ? -16.130 0.535 -25.462 1.00 18.21 ? 508 THR A CG2 1 ATOM 4036 N N . ALA A 1 509 ? -16.141 3.828 -27.496 1.00 20.44 ? 509 ALA A N 1 ATOM 4037 C CA . ALA A 1 509 ? -16.819 4.229 -28.751 1.00 21.33 ? 509 ALA A CA 1 ATOM 4038 C C . ALA A 1 509 ? -15.768 4.436 -29.870 1.00 22.24 ? 509 ALA A C 1 ATOM 4039 O O . ALA A 1 509 ? -15.939 3.982 -31.009 1.00 21.90 ? 509 ALA A O 1 ATOM 4040 C CB . ALA A 1 509 ? -17.623 5.492 -28.537 1.00 21.97 ? 509 ALA A CB 1 ATOM 4041 N N . GLU A 1 510 ? -14.656 5.068 -29.531 1.00 22.99 ? 510 GLU A N 1 ATOM 4042 C CA . GLU A 1 510 ? -13.566 5.223 -30.495 1.00 24.63 ? 510 GLU A CA 1 ATOM 4043 C C . GLU A 1 510 ? -13.122 3.861 -31.021 1.00 23.33 ? 510 GLU A C 1 ATOM 4044 O O . GLU A 1 510 ? -12.968 3.697 -32.239 1.00 23.73 ? 510 GLU A O 1 ATOM 4045 C CB . GLU A 1 510 ? -12.403 6.016 -29.868 1.00 25.38 ? 510 GLU A CB 1 ATOM 4046 C CG . GLU A 1 510 ? -11.294 6.472 -30.834 1.00 32.62 ? 510 GLU A CG 1 ATOM 4047 C CD . GLU A 1 510 ? -11.767 7.489 -31.902 1.00 41.00 ? 510 GLU A CD 1 ATOM 4048 O OE1 . GLU A 1 510 ? -12.720 8.273 -31.647 1.00 44.06 ? 510 GLU A OE1 1 ATOM 4049 O OE2 . GLU A 1 510 ? -11.176 7.495 -33.011 1.00 45.93 ? 510 GLU A OE2 1 ATOM 4050 N N . ALA A 1 511 ? -12.946 2.877 -30.125 1.00 22.69 ? 511 ALA A N 1 ATOM 4051 C CA . ALA A 1 511 ? -12.561 1.521 -30.507 1.00 21.98 ? 511 ALA A CA 1 ATOM 4052 C C . ALA A 1 511 ? -13.597 0.866 -31.438 1.00 22.19 ? 511 ALA A C 1 ATOM 4053 O O . ALA A 1 511 ? -13.243 0.125 -32.381 1.00 20.94 ? 511 ALA A O 1 ATOM 4054 C CB . ALA A 1 511 ? -12.328 0.638 -29.250 1.00 22.31 ? 511 ALA A CB 1 ATOM 4055 N N . ALA A 1 512 ? -14.883 1.122 -31.172 1.00 21.80 ? 512 ALA A N 1 ATOM 4056 C CA . ALA A 1 512 ? -15.945 0.583 -31.990 1.00 22.84 ? 512 ALA A CA 1 ATOM 4057 C C . ALA A 1 512 ? -15.843 1.038 -33.454 1.00 23.24 ? 512 ALA A C 1 ATOM 4058 O O . ALA A 1 512 ? -16.248 0.302 -34.352 1.00 24.32 ? 512 ALA A O 1 ATOM 4059 C CB . ALA A 1 512 ? -17.354 0.953 -31.386 1.00 22.12 ? 512 ALA A CB 1 ATOM 4060 N N . LYS A 1 513 ? -15.308 2.229 -33.695 1.00 24.60 ? 513 LYS A N 1 ATOM 4061 C CA . LYS A 1 513 ? -15.127 2.744 -35.065 1.00 26.67 ? 513 LYS A CA 1 ATOM 4062 C C . LYS A 1 513 ? -14.270 1.804 -35.904 1.00 26.51 ? 513 LYS A C 1 ATOM 4063 O O . LYS A 1 513 ? -14.432 1.731 -37.121 1.00 26.87 ? 513 LYS A O 1 ATOM 4064 C CB . LYS A 1 513 ? -14.448 4.119 -35.077 1.00 26.50 ? 513 LYS A CB 1 ATOM 4065 C CG . LYS A 1 513 ? -15.212 5.261 -34.435 1.00 27.79 ? 513 LYS A CG 1 ATOM 4066 C CD . LYS A 1 513 ? -14.423 6.561 -34.600 1.00 29.00 ? 513 LYS A CD 1 ATOM 4067 C CE . LYS A 1 513 ? -15.160 7.736 -33.970 1.00 34.03 ? 513 LYS A CE 1 ATOM 4068 N NZ . LYS A 1 513 ? -14.330 8.988 -34.053 1.00 39.20 ? 513 LYS A NZ 1 ATOM 4069 N N . THR A 1 514 ? -13.332 1.112 -35.258 1.00 26.68 ? 514 THR A N 1 ATOM 4070 C CA . THR A 1 514 ? -12.412 0.200 -35.955 1.00 24.96 ? 514 THR A CA 1 ATOM 4071 C C . THR A 1 514 ? -12.930 -1.209 -35.921 1.00 24.38 ? 514 THR A C 1 ATOM 4072 O O . THR A 1 514 ? -12.933 -1.900 -36.939 1.00 23.73 ? 514 THR A O 1 ATOM 4073 C CB . THR A 1 514 ? -11.009 0.253 -35.310 1.00 26.20 ? 514 THR A CB 1 ATOM 4074 O OG1 . THR A 1 514 ? -10.426 1.508 -35.623 1.00 25.74 ? 514 THR A OG1 1 ATOM 4075 C CG2 . THR A 1 514 ? -10.097 -0.833 -35.857 1.00 27.40 ? 514 THR A CG2 1 ATOM 4076 N N . VAL A 1 515 ? -13.401 -1.646 -34.748 1.00 22.17 ? 515 VAL A N 1 ATOM 4077 C CA . VAL A 1 515 ? -13.785 -3.040 -34.570 1.00 22.86 ? 515 VAL A CA 1 ATOM 4078 C C . VAL A 1 515 ? -15.146 -3.338 -35.264 1.00 22.13 ? 515 VAL A C 1 ATOM 4079 O O . VAL A 1 515 ? -15.373 -4.430 -35.800 1.00 21.67 ? 515 VAL A O 1 ATOM 4080 C CB . VAL A 1 515 ? -13.852 -3.366 -33.069 1.00 22.96 ? 515 VAL A CB 1 ATOM 4081 C CG1 . VAL A 1 515 ? -14.499 -4.742 -32.818 1.00 24.38 ? 515 VAL A CG1 1 ATOM 4082 C CG2 . VAL A 1 515 ? -12.457 -3.268 -32.457 1.00 24.59 ? 515 VAL A CG2 1 ATOM 4083 N N . PHE A 1 516 ? -16.024 -2.346 -35.269 1.00 22.06 ? 516 PHE A N 1 ATOM 4084 C CA . PHE A 1 516 ? -17.371 -2.490 -35.879 1.00 22.46 ? 516 PHE A CA 1 ATOM 4085 C C . PHE A 1 516 ? -17.571 -1.394 -36.925 1.00 23.47 ? 516 PHE A C 1 ATOM 4086 O O . PHE A 1 516 ? -18.305 -0.437 -36.679 1.00 22.68 ? 516 PHE A O 1 ATOM 4087 C CB . PHE A 1 516 ? -18.455 -2.365 -34.794 1.00 23.08 ? 516 PHE A CB 1 ATOM 4088 C CG . PHE A 1 516 ? -18.341 -3.397 -33.718 1.00 22.35 ? 516 PHE A CG 1 ATOM 4089 C CD1 . PHE A 1 516 ? -18.484 -4.748 -34.017 1.00 23.84 ? 516 PHE A CD1 1 ATOM 4090 C CD2 . PHE A 1 516 ? -18.069 -3.019 -32.415 1.00 21.76 ? 516 PHE A CD2 1 ATOM 4091 C CE1 . PHE A 1 516 ? -18.360 -5.702 -33.011 1.00 26.74 ? 516 PHE A CE1 1 ATOM 4092 C CE2 . PHE A 1 516 ? -17.957 -3.961 -31.403 1.00 22.42 ? 516 PHE A CE2 1 ATOM 4093 C CZ . PHE A 1 516 ? -18.099 -5.289 -31.693 1.00 22.85 ? 516 PHE A CZ 1 ATOM 4094 N N . PRO A 1 517 ? -16.870 -1.486 -38.069 1.00 24.30 ? 517 PRO A N 1 ATOM 4095 C CA . PRO A 1 517 ? -16.874 -0.331 -38.967 1.00 25.34 ? 517 PRO A CA 1 ATOM 4096 C C . PRO A 1 517 ? -18.274 0.039 -39.440 1.00 24.89 ? 517 PRO A C 1 ATOM 4097 O O . PRO A 1 517 ? -18.999 -0.818 -39.920 1.00 24.56 ? 517 PRO A O 1 ATOM 4098 C CB . PRO A 1 517 ? -16.000 -0.804 -40.154 1.00 25.31 ? 517 PRO A CB 1 ATOM 4099 C CG . PRO A 1 517 ? -15.090 -1.768 -39.556 1.00 24.94 ? 517 PRO A CG 1 ATOM 4100 C CD . PRO A 1 517 ? -15.982 -2.544 -38.586 1.00 25.12 ? 517 PRO A CD 1 ATOM 4101 N N . ASN A 1 518 ? -18.609 1.308 -39.250 1.00 25.28 ? 518 ASN A N 1 ATOM 4102 C CA . ASN A 1 518 ? -19.900 1.908 -39.590 1.00 26.32 ? 518 ASN A CA 1 ATOM 4103 C C . ASN A 1 518 ? -21.127 1.364 -38.887 1.00 25.26 ? 518 ASN A C 1 ATOM 4104 O O . ASN A 1 518 ? -22.230 1.625 -39.344 1.00 25.59 ? 518 ASN A O 1 ATOM 4105 C CB . ASN A 1 518 ? -20.121 1.888 -41.102 1.00 27.89 ? 518 ASN A CB 1 ATOM 4106 C CG . ASN A 1 518 ? -19.067 2.682 -41.825 1.00 31.90 ? 518 ASN A CG 1 ATOM 4107 O OD1 . ASN A 1 518 ? -18.918 3.891 -41.592 1.00 36.88 ? 518 ASN A OD1 1 ATOM 4108 N ND2 . ASN A 1 518 ? -18.299 2.004 -42.689 1.00 36.60 ? 518 ASN A ND2 1 ATOM 4109 N N . LYS A 1 519 ? -20.927 0.618 -37.799 1.00 23.90 ? 519 LYS A N 1 ATOM 4110 C CA . LYS A 1 519 ? -22.027 0.091 -36.989 1.00 22.93 ? 519 LYS A CA 1 ATOM 4111 C C . LYS A 1 519 ? -22.089 0.806 -35.654 1.00 22.10 ? 519 LYS A C 1 ATOM 4112 O O . LYS A 1 519 ? -21.074 1.353 -35.171 1.00 21.37 ? 519 LYS A O 1 ATOM 4113 C CB . LYS A 1 519 ? -21.906 -1.438 -36.762 1.00 23.96 ? 519 LYS A CB 1 ATOM 4114 C CG . LYS A 1 519 ? -21.774 -2.305 -38.048 1.00 25.69 ? 519 LYS A CG 1 ATOM 4115 C CD . LYS A 1 519 ? -22.968 -2.150 -39.000 1.00 29.89 ? 519 LYS A CD 1 ATOM 4116 C CE . LYS A 1 519 ? -22.679 -2.817 -40.374 1.00 31.23 ? 519 LYS A CE 1 ATOM 4117 N NZ . LYS A 1 519 ? -23.948 -2.890 -41.170 1.00 35.32 ? 519 LYS A NZ 1 ATOM 4118 N N . ARG A 1 520 ? -23.292 0.802 -35.058 1.00 19.76 ? 520 ARG A N 1 ATOM 4119 C CA . ARG A 1 520 ? -23.501 1.368 -33.726 1.00 18.69 ? 520 ARG A CA 1 ATOM 4120 C C . ARG A 1 520 ? -22.885 0.485 -32.636 1.00 17.96 ? 520 ARG A C 1 ATOM 4121 O O . ARG A 1 520 ? -22.392 1.022 -31.645 1.00 18.85 ? 520 ARG A O 1 ATOM 4122 C CB . ARG A 1 520 ? -25.014 1.537 -33.437 1.00 18.14 ? 520 ARG A CB 1 ATOM 4123 C CG . ARG A 1 520 ? -25.652 2.560 -34.343 1.00 16.33 ? 520 ARG A CG 1 ATOM 4124 C CD . ARG A 1 520 ? -27.172 2.378 -34.321 1.00 18.10 ? 520 ARG A CD 1 ATOM 4125 N NE . ARG A 1 520 ? -27.680 2.907 -35.568 1.00 16.52 ? 520 ARG A NE 1 ATOM 4126 C CZ . ARG A 1 520 ? -28.963 2.936 -35.902 1.00 19.25 ? 520 ARG A CZ 1 ATOM 4127 N NH1 . ARG A 1 520 ? -29.868 2.479 -35.052 1.00 12.61 ? 520 ARG A NH1 1 ATOM 4128 N NH2 . ARG A 1 520 ? -29.314 3.411 -37.087 1.00 18.02 ? 520 ARG A NH2 1 ATOM 4129 N N . SER A 1 521 ? -23.009 -0.833 -32.790 1.00 17.15 ? 521 SER A N 1 ATOM 4130 C CA . SER A 1 521 ? -22.673 -1.799 -31.739 1.00 16.67 ? 521 SER A CA 1 ATOM 4131 C C . SER A 1 521 ? -23.519 -1.433 -30.503 1.00 17.46 ? 521 SER A C 1 ATOM 4132 O O . SER A 1 521 ? -24.695 -0.971 -30.650 1.00 17.54 ? 521 SER A O 1 ATOM 4133 C CB . SER A 1 521 ? -21.148 -1.750 -31.490 1.00 15.82 ? 521 SER A CB 1 ATOM 4134 O OG . SER A 1 521 ? -20.779 -2.689 -30.501 1.00 16.75 ? 521 SER A OG 1 ATOM 4135 N N . PHE A 1 522 ? -22.955 -1.605 -29.315 1.00 16.83 ? 522 PHE A N 1 ATOM 4136 C CA . PHE A 1 522 ? -23.643 -1.391 -28.037 1.00 16.73 ? 522 PHE A CA 1 ATOM 4137 C C . PHE A 1 522 ? -22.531 -1.256 -26.998 1.00 16.14 ? 522 PHE A C 1 ATOM 4138 O O . PHE A 1 522 ? -21.652 -2.104 -26.954 1.00 15.67 ? 522 PHE A O 1 ATOM 4139 C CB . PHE A 1 522 ? -24.449 -2.640 -27.710 1.00 16.42 ? 522 PHE A CB 1 ATOM 4140 C CG . PHE A 1 522 ? -25.081 -2.659 -26.341 1.00 17.62 ? 522 PHE A CG 1 ATOM 4141 C CD1 . PHE A 1 522 ? -26.149 -1.811 -26.045 1.00 15.61 ? 522 PHE A CD1 1 ATOM 4142 C CD2 . PHE A 1 522 ? -24.650 -3.565 -25.359 1.00 14.72 ? 522 PHE A CD2 1 ATOM 4143 C CE1 . PHE A 1 522 ? -26.737 -1.852 -24.766 1.00 17.11 ? 522 PHE A CE1 1 ATOM 4144 C CE2 . PHE A 1 522 ? -25.244 -3.616 -24.103 1.00 17.53 ? 522 PHE A CE2 1 ATOM 4145 C CZ . PHE A 1 522 ? -26.296 -2.765 -23.810 1.00 15.54 ? 522 PHE A CZ 1 ATOM 4146 N N . ILE A 1 523 ? -22.581 -0.207 -26.188 1.00 15.46 ? 523 ILE A N 1 ATOM 4147 C CA . ILE A 1 523 ? -21.734 -0.092 -25.020 1.00 16.23 ? 523 ILE A CA 1 ATOM 4148 C C . ILE A 1 523 ? -22.598 0.114 -23.825 1.00 16.21 ? 523 ILE A C 1 ATOM 4149 O O . ILE A 1 523 ? -23.490 0.961 -23.844 1.00 17.45 ? 523 ILE A O 1 ATOM 4150 C CB . ILE A 1 523 ? -20.776 1.081 -25.124 1.00 15.88 ? 523 ILE A CB 1 ATOM 4151 C CG1 . ILE A 1 523 ? -19.907 0.899 -26.381 1.00 16.68 ? 523 ILE A CG1 1 ATOM 4152 C CG2 . ILE A 1 523 ? -19.939 1.228 -23.796 1.00 15.14 ? 523 ILE A CG2 1 ATOM 4153 C CD1 . ILE A 1 523 ? -19.166 2.158 -26.765 1.00 20.19 ? 523 ILE A CD1 1 ATOM 4154 N N . LEU A 1 524 ? -22.374 -0.692 -22.792 1.00 16.05 ? 524 LEU A N 1 ATOM 4155 C CA . LEU A 1 524 ? -23.097 -0.579 -21.516 1.00 15.97 ? 524 LEU A CA 1 ATOM 4156 C C . LEU A 1 524 ? -22.071 -0.184 -20.459 1.00 16.97 ? 524 LEU A C 1 ATOM 4157 O O . LEU A 1 524 ? -21.082 -0.892 -20.319 1.00 19.21 ? 524 LEU A O 1 ATOM 4158 C CB . LEU A 1 524 ? -23.688 -1.914 -21.158 1.00 15.79 ? 524 LEU A CB 1 ATOM 4159 C CG . LEU A 1 524 ? -24.449 -2.048 -19.835 1.00 16.40 ? 524 LEU A CG 1 ATOM 4160 C CD1 . LEU A 1 524 ? -25.780 -1.177 -19.811 1.00 14.78 ? 524 LEU A CD1 1 ATOM 4161 C CD2 . LEU A 1 524 ? -24.760 -3.496 -19.542 1.00 14.92 ? 524 LEU A CD2 1 ATOM 4162 N N . THR A 1 525 ? -22.285 0.901 -19.711 1.00 16.25 ? 525 THR A N 1 ATOM 4163 C CA . THR A 1 525 ? -21.270 1.364 -18.723 1.00 17.10 ? 525 THR A CA 1 ATOM 4164 C C . THR A 1 525 ? -21.874 1.485 -17.340 1.00 18.36 ? 525 THR A C 1 ATOM 4165 O O . THR A 1 525 ? -23.078 1.741 -17.184 1.00 17.67 ? 525 THR A O 1 ATOM 4166 C CB . THR A 1 525 ? -20.618 2.719 -19.127 1.00 17.53 ? 525 THR A CB 1 ATOM 4167 O OG1 . THR A 1 525 ? -19.571 3.083 -18.204 1.00 16.42 ? 525 THR A OG1 1 ATOM 4168 C CG2 . THR A 1 525 ? -21.665 3.824 -19.136 1.00 15.64 ? 525 THR A CG2 1 ATOM 4169 N N . ARG A 1 526 ? -21.044 1.249 -16.330 1.00 17.08 ? 526 ARG A N 1 ATOM 4170 C CA . ARG A 1 526 ? -21.484 1.437 -14.970 1.00 17.35 ? 526 ARG A CA 1 ATOM 4171 C C . ARG A 1 526 ? -21.351 2.896 -14.559 1.00 17.18 ? 526 ARG A C 1 ATOM 4172 O O . ARG A 1 526 ? -22.348 3.534 -14.243 1.00 17.04 ? 526 ARG A O 1 ATOM 4173 C CB . ARG A 1 526 ? -20.751 0.503 -13.976 1.00 16.88 ? 526 ARG A CB 1 ATOM 4174 C CG . ARG A 1 526 ? -21.577 0.347 -12.665 1.00 17.77 ? 526 ARG A CG 1 ATOM 4175 C CD . ARG A 1 526 ? -21.148 -0.864 -11.867 1.00 17.34 ? 526 ARG A CD 1 ATOM 4176 N NE . ARG A 1 526 ? -19.895 -0.560 -11.215 1.00 21.10 ? 526 ARG A NE 1 ATOM 4177 C CZ . ARG A 1 526 ? -19.205 -1.391 -10.440 1.00 22.96 ? 526 ARG A CZ 1 ATOM 4178 N NH1 . ARG A 1 526 ? -19.632 -2.626 -10.219 1.00 26.22 ? 526 ARG A NH1 1 ATOM 4179 N NH2 . ARG A 1 526 ? -18.054 -0.971 -9.909 1.00 22.02 ? 526 ARG A NH2 1 ATOM 4180 N N . SER A 1 527 ? -20.120 3.421 -14.563 1.00 15.79 ? 527 SER A N 1 ATOM 4181 C CA . SER A 1 527 ? -19.851 4.796 -14.182 1.00 16.86 ? 527 SER A CA 1 ATOM 4182 C C . SER A 1 527 ? -20.180 5.768 -15.335 1.00 16.47 ? 527 SER A C 1 ATOM 4183 O O . SER A 1 527 ? -19.926 5.451 -16.491 1.00 17.32 ? 527 SER A O 1 ATOM 4184 C CB . SER A 1 527 ? -18.363 4.950 -13.806 1.00 17.48 ? 527 SER A CB 1 ATOM 4185 O OG . SER A 1 527 ? -18.139 6.221 -13.278 1.00 22.06 ? 527 SER A OG 1 ATOM 4186 N N . THR A 1 528 ? -20.797 6.896 -15.011 1.00 16.53 ? 528 THR A N 1 ATOM 4187 C CA . THR A 1 528 ? -21.249 7.896 -16.011 1.00 15.93 ? 528 THR A CA 1 ATOM 4188 C C . THR A 1 528 ? -20.909 9.274 -15.485 1.00 16.01 ? 528 THR A C 1 ATOM 4189 O O . THR A 1 528 ? -20.773 9.479 -14.294 1.00 16.20 ? 528 THR A O 1 ATOM 4190 C CB . THR A 1 528 ? -22.807 7.866 -16.297 1.00 16.00 ? 528 THR A CB 1 ATOM 4191 O OG1 . THR A 1 528 ? -23.515 8.179 -15.100 1.00 16.49 ? 528 THR A OG1 1 ATOM 4192 C CG2 . THR A 1 528 ? -23.273 6.517 -16.827 1.00 18.06 ? 528 THR A CG2 1 ATOM 4193 N N . PHE A 1 529 ? -20.798 10.232 -16.394 1.00 14.87 ? 529 PHE A N 1 ATOM 4194 C CA . PHE A 1 529 ? -20.768 11.616 -16.063 1.00 15.11 ? 529 PHE A CA 1 ATOM 4195 C C . PHE A 1 529 ? -21.839 12.237 -17.002 1.00 14.85 ? 529 PHE A C 1 ATOM 4196 O O . PHE A 1 529 ? -22.398 11.545 -17.858 1.00 15.89 ? 529 PHE A O 1 ATOM 4197 C CB . PHE A 1 529 ? -19.346 12.168 -16.327 1.00 14.92 ? 529 PHE A CB 1 ATOM 4198 C CG . PHE A 1 529 ? -19.139 13.568 -15.856 1.00 15.47 ? 529 PHE A CG 1 ATOM 4199 C CD1 . PHE A 1 529 ? -19.138 13.867 -14.495 1.00 17.04 ? 529 PHE A CD1 1 ATOM 4200 C CD2 . PHE A 1 529 ? -18.962 14.595 -16.766 1.00 18.96 ? 529 PHE A CD2 1 ATOM 4201 C CE1 . PHE A 1 529 ? -18.968 15.179 -14.041 1.00 17.26 ? 529 PHE A CE1 1 ATOM 4202 C CE2 . PHE A 1 529 ? -18.797 15.925 -16.337 1.00 19.27 ? 529 PHE A CE2 1 ATOM 4203 C CZ . PHE A 1 529 ? -18.799 16.221 -14.967 1.00 17.83 ? 529 PHE A CZ 1 ATOM 4204 N N . ALA A 1 530 ? -22.136 13.505 -16.820 1.00 14.18 ? 530 ALA A N 1 ATOM 4205 C CA . ALA A 1 530 ? -23.020 14.229 -17.730 1.00 16.08 ? 530 ALA A CA 1 ATOM 4206 C C . ALA A 1 530 ? -22.529 14.096 -19.181 1.00 16.49 ? 530 ALA A C 1 ATOM 4207 O O . ALA A 1 530 ? -21.370 14.395 -19.498 1.00 17.50 ? 530 ALA A O 1 ATOM 4208 C CB . ALA A 1 530 ? -23.077 15.675 -17.302 1.00 15.07 ? 530 ALA A CB 1 ATOM 4209 N N . GLY A 1 531 ? -23.407 13.620 -20.049 1.00 17.30 ? 531 GLY A N 1 ATOM 4210 C CA . GLY A 1 531 ? -23.058 13.370 -21.458 1.00 16.95 ? 531 GLY A CA 1 ATOM 4211 C C . GLY A 1 531 ? -22.682 11.951 -21.832 1.00 16.51 ? 531 GLY A C 1 ATOM 4212 O O . GLY A 1 531 ? -22.439 11.666 -23.002 1.00 15.77 ? 531 GLY A O 1 ATOM 4213 N N . SER A 1 532 ? -22.612 11.037 -20.859 1.00 16.60 ? 532 SER A N 1 ATOM 4214 C CA . SER A 1 532 ? -22.242 9.638 -21.154 1.00 14.81 ? 532 SER A CA 1 ATOM 4215 C C . SER A 1 532 ? -23.227 8.944 -22.087 1.00 14.55 ? 532 SER A C 1 ATOM 4216 O O . SER A 1 532 ? -22.858 7.988 -22.800 1.00 13.97 ? 532 SER A O 1 ATOM 4217 C CB . SER A 1 532 ? -22.128 8.775 -19.873 1.00 14.83 ? 532 SER A CB 1 ATOM 4218 O OG . SER A 1 532 ? -20.904 9.077 -19.190 1.00 15.01 ? 532 SER A OG 1 ATOM 4219 N N . GLY A 1 533 ? -24.476 9.384 -22.047 1.00 15.05 ? 533 GLY A N 1 ATOM 4220 C CA . GLY A 1 533 ? -25.514 8.775 -22.906 1.00 14.43 ? 533 GLY A CA 1 ATOM 4221 C C . GLY A 1 533 ? -25.205 8.900 -24.417 1.00 15.36 ? 533 GLY A C 1 ATOM 4222 O O . GLY A 1 533 ? -25.745 8.131 -25.239 1.00 14.38 ? 533 GLY A O 1 ATOM 4223 N N . LYS A 1 534 ? -24.362 9.865 -24.794 1.00 14.59 ? 534 LYS A N 1 ATOM 4224 C CA . LYS A 1 534 ? -23.966 10.020 -26.198 1.00 16.87 ? 534 LYS A CA 1 ATOM 4225 C C . LYS A 1 534 ? -23.222 8.764 -26.672 1.00 17.85 ? 534 LYS A C 1 ATOM 4226 O O . LYS A 1 534 ? -23.191 8.446 -27.854 1.00 19.04 ? 534 LYS A O 1 ATOM 4227 C CB . LYS A 1 534 ? -23.128 11.313 -26.361 1.00 17.19 ? 534 LYS A CB 1 ATOM 4228 C CG . LYS A 1 534 ? -22.573 11.596 -27.728 1.00 18.45 ? 534 LYS A CG 1 ATOM 4229 C CD . LYS A 1 534 ? -21.828 12.937 -27.752 1.00 19.09 ? 534 LYS A CD 1 ATOM 4230 C CE . LYS A 1 534 ? -21.072 13.170 -29.110 1.00 21.69 ? 534 LYS A CE 1 ATOM 4231 N NZ . LYS A 1 534 ? -20.074 14.299 -29.002 1.00 23.98 ? 534 LYS A NZ 1 ATOM 4232 N N . PHE A 1 535 ? -22.660 8.021 -25.725 1.00 18.02 ? 535 PHE A N 1 ATOM 4233 C CA . PHE A 1 535 ? -21.822 6.850 -26.016 1.00 18.08 ? 535 PHE A CA 1 ATOM 4234 C C . PHE A 1 535 ? -22.386 5.519 -25.560 1.00 18.47 ? 535 PHE A C 1 ATOM 4235 O O . PHE A 1 535 ? -22.109 4.470 -26.172 1.00 18.75 ? 535 PHE A O 1 ATOM 4236 C CB . PHE A 1 535 ? -20.445 7.050 -25.365 1.00 19.12 ? 535 PHE A CB 1 ATOM 4237 C CG . PHE A 1 535 ? -19.804 8.330 -25.764 1.00 22.64 ? 535 PHE A CG 1 ATOM 4238 C CD1 . PHE A 1 535 ? -19.191 8.456 -27.012 1.00 23.37 ? 535 PHE A CD1 1 ATOM 4239 C CD2 . PHE A 1 535 ? -19.858 9.442 -24.922 1.00 23.90 ? 535 PHE A CD2 1 ATOM 4240 C CE1 . PHE A 1 535 ? -18.631 9.672 -27.412 1.00 25.27 ? 535 PHE A CE1 1 ATOM 4241 C CE2 . PHE A 1 535 ? -19.308 10.650 -25.328 1.00 26.77 ? 535 PHE A CE2 1 ATOM 4242 C CZ . PHE A 1 535 ? -18.687 10.755 -26.571 1.00 23.68 ? 535 PHE A CZ 1 ATOM 4243 N N . ALA A 1 536 ? -23.147 5.512 -24.471 1.00 16.00 ? 536 ALA A N 1 ATOM 4244 C CA . ALA A 1 536 ? -23.367 4.256 -23.815 1.00 15.50 ? 536 ALA A CA 1 ATOM 4245 C C . ALA A 1 536 ? -24.739 4.176 -23.168 1.00 15.16 ? 536 ALA A C 1 ATOM 4246 O O . ALA A 1 536 ? -25.313 5.204 -22.839 1.00 16.37 ? 536 ALA A O 1 ATOM 4247 C CB . ALA A 1 536 ? -22.297 4.077 -22.753 1.00 15.52 ? 536 ALA A CB 1 ATOM 4248 N N . ALA A 1 537 ? -25.240 2.955 -23.011 1.00 15.04 ? 537 ALA A N 1 ATOM 4249 C CA . ALA A 1 537 ? -26.303 2.591 -22.091 1.00 14.53 ? 537 ALA A CA 1 ATOM 4250 C C . ALA A 1 537 ? -25.781 2.492 -20.633 1.00 14.94 ? 537 ALA A C 1 ATOM 4251 O O . ALA A 1 537 ? -24.556 2.438 -20.373 1.00 14.72 ? 537 ALA A O 1 ATOM 4252 C CB . ALA A 1 537 ? -26.928 1.232 -22.530 1.00 14.84 ? 537 ALA A CB 1 ATOM 4253 N N . HIS A 1 538 ? -26.709 2.380 -19.692 1.00 13.99 ? 538 HIS A N 1 ATOM 4254 C CA . HIS A 1 538 ? -26.356 2.260 -18.290 1.00 15.12 ? 538 HIS A CA 1 ATOM 4255 C C . HIS A 1 538 ? -27.217 1.240 -17.605 1.00 15.46 ? 538 HIS A C 1 ATOM 4256 O O . HIS A 1 538 ? -28.415 1.077 -17.948 1.00 16.31 ? 538 HIS A O 1 ATOM 4257 C CB . HIS A 1 538 ? -26.455 3.650 -17.592 1.00 13.63 ? 538 HIS A CB 1 ATOM 4258 C CG . HIS A 1 538 ? -26.212 3.622 -16.108 1.00 16.31 ? 538 HIS A CG 1 ATOM 4259 N ND1 . HIS A 1 538 ? -25.004 3.234 -15.549 1.00 15.07 ? 538 HIS A ND1 1 ATOM 4260 C CD2 . HIS A 1 538 ? -27.016 3.963 -15.067 1.00 17.59 ? 538 HIS A CD2 1 ATOM 4261 C CE1 . HIS A 1 538 ? -25.074 3.348 -14.234 1.00 16.44 ? 538 HIS A CE1 1 ATOM 4262 N NE2 . HIS A 1 538 ? -26.286 3.785 -13.912 1.00 17.73 ? 538 HIS A NE2 1 ATOM 4263 N N . TRP A 1 539 ? -26.654 0.524 -16.631 1.00 16.03 ? 539 TRP A N 1 ATOM 4264 C CA . TRP A 1 539 ? -27.527 -0.215 -15.707 1.00 16.65 ? 539 TRP A CA 1 ATOM 4265 C C . TRP A 1 539 ? -27.334 0.243 -14.275 1.00 16.61 ? 539 TRP A C 1 ATOM 4266 O O . TRP A 1 539 ? -26.258 0.760 -13.897 1.00 17.02 ? 539 TRP A O 1 ATOM 4267 C CB . TRP A 1 539 ? -27.464 -1.764 -15.834 1.00 16.59 ? 539 TRP A CB 1 ATOM 4268 C CG . TRP A 1 539 ? -26.401 -2.429 -14.994 1.00 16.75 ? 539 TRP A CG 1 ATOM 4269 C CD1 . TRP A 1 539 ? -26.583 -3.261 -13.910 1.00 16.65 ? 539 TRP A CD1 1 ATOM 4270 C CD2 . TRP A 1 539 ? -24.993 -2.328 -15.195 1.00 16.61 ? 539 TRP A CD2 1 ATOM 4271 N NE1 . TRP A 1 539 ? -25.336 -3.677 -13.432 1.00 17.77 ? 539 TRP A NE1 1 ATOM 4272 C CE2 . TRP A 1 539 ? -24.361 -3.120 -14.206 1.00 16.78 ? 539 TRP A CE2 1 ATOM 4273 C CE3 . TRP A 1 539 ? -24.203 -1.665 -16.138 1.00 17.82 ? 539 TRP A CE3 1 ATOM 4274 C CZ2 . TRP A 1 539 ? -22.974 -3.248 -14.115 1.00 16.45 ? 539 TRP A CZ2 1 ATOM 4275 C CZ3 . TRP A 1 539 ? -22.822 -1.776 -16.040 1.00 18.04 ? 539 TRP A CZ3 1 ATOM 4276 C CH2 . TRP A 1 539 ? -22.221 -2.569 -15.031 1.00 17.89 ? 539 TRP A CH2 1 ATOM 4277 N N . LEU A 1 540 ? -28.375 0.051 -13.472 1.00 16.66 ? 540 LEU A N 1 ATOM 4278 C CA . LEU A 1 540 ? -28.413 0.693 -12.168 1.00 16.71 ? 540 LEU A CA 1 ATOM 4279 C C . LEU A 1 540 ? -27.565 -0.051 -11.116 1.00 17.26 ? 540 LEU A C 1 ATOM 4280 O O . LEU A 1 540 ? -27.649 0.250 -9.921 1.00 17.40 ? 540 LEU A O 1 ATOM 4281 C CB . LEU A 1 540 ? -29.869 0.828 -11.701 1.00 17.32 ? 540 LEU A CB 1 ATOM 4282 C CG . LEU A 1 540 ? -30.657 1.762 -12.633 1.00 17.73 ? 540 LEU A CG 1 ATOM 4283 C CD1 . LEU A 1 540 ? -32.131 1.744 -12.245 1.00 18.36 ? 540 LEU A CD1 1 ATOM 4284 C CD2 . LEU A 1 540 ? -30.101 3.203 -12.620 1.00 19.22 ? 540 LEU A CD2 1 ATOM 4285 N N . GLY A 1 541 ? -26.798 -1.038 -11.563 1.00 16.68 ? 541 GLY A N 1 ATOM 4286 C CA . GLY A 1 541 ? -25.710 -1.648 -10.742 1.00 17.48 ? 541 GLY A CA 1 ATOM 4287 C C . GLY A 1 541 ? -26.158 -2.868 -9.960 1.00 17.59 ? 541 GLY A C 1 ATOM 4288 O O . GLY A 1 541 ? -27.194 -3.487 -10.290 1.00 17.05 ? 541 GLY A O 1 ATOM 4289 N N . ASP A 1 542 ? -25.431 -3.159 -8.881 1.00 16.98 ? 542 ASP A N 1 ATOM 4290 C CA . ASP A 1 542 ? -25.583 -4.370 -8.047 1.00 18.06 ? 542 ASP A CA 1 ATOM 4291 C C . ASP A 1 542 ? -26.740 -4.317 -7.033 1.00 18.54 ? 542 ASP A C 1 ATOM 4292 O O . ASP A 1 542 ? -26.537 -4.192 -5.820 1.00 19.89 ? 542 ASP A O 1 ATOM 4293 C CB . ASP A 1 542 ? -24.252 -4.631 -7.325 1.00 19.19 ? 542 ASP A CB 1 ATOM 4294 C CG . ASP A 1 542 ? -23.077 -4.767 -8.288 1.00 23.05 ? 542 ASP A CG 1 ATOM 4295 O OD1 . ASP A 1 542 ? -23.267 -5.303 -9.415 1.00 27.81 ? 542 ASP A OD1 1 ATOM 4296 O OD2 . ASP A 1 542 ? -21.940 -4.381 -7.906 1.00 27.97 ? 542 ASP A OD2 1 ATOM 4297 N N . ASN A 1 543 ? -27.964 -4.431 -7.534 1.00 16.63 ? 543 ASN A N 1 ATOM 4298 C CA . ASN A 1 543 ? -29.127 -4.399 -6.676 1.00 16.58 ? 543 ASN A CA 1 ATOM 4299 C C . ASN A 1 543 ? -29.377 -5.759 -5.989 1.00 17.07 ? 543 ASN A C 1 ATOM 4300 O O . ASN A 1 543 ? -28.561 -6.688 -6.071 1.00 16.58 ? 543 ASN A O 1 ATOM 4301 C CB . ASN A 1 543 ? -30.358 -3.920 -7.499 1.00 15.78 ? 543 ASN A CB 1 ATOM 4302 C CG . ASN A 1 543 ? -30.779 -4.919 -8.569 1.00 15.70 ? 543 ASN A CG 1 ATOM 4303 O OD1 . ASN A 1 543 ? -30.075 -5.872 -8.843 1.00 18.17 ? 543 ASN A OD1 1 ATOM 4304 N ND2 . ASN A 1 543 ? -31.979 -4.733 -9.149 1.00 16.66 ? 543 ASN A ND2 1 ATOM 4305 N N . THR A 1 544 ? -30.534 -5.907 -5.345 1.00 18.41 ? 544 THR A N 1 ATOM 4306 C CA . THR A 1 544 ? -30.763 -7.056 -4.505 1.00 18.74 ? 544 THR A CA 1 ATOM 4307 C C . THR A 1 544 ? -32.158 -7.546 -4.836 1.00 19.24 ? 544 THR A C 1 ATOM 4308 O O . THR A 1 544 ? -32.991 -6.734 -5.257 1.00 16.42 ? 544 THR A O 1 ATOM 4309 C CB . THR A 1 544 ? -30.621 -6.628 -3.016 1.00 19.89 ? 544 THR A CB 1 ATOM 4310 O OG1 . THR A 1 544 ? -29.345 -5.975 -2.868 1.00 23.82 ? 544 THR A OG1 1 ATOM 4311 C CG2 . THR A 1 544 ? -30.612 -7.826 -2.079 1.00 21.77 ? 544 THR A CG2 1 ATOM 4312 N N . ALA A 1 545 ? -32.388 -8.856 -4.693 1.00 18.26 ? 545 ALA A N 1 ATOM 4313 C CA . ALA A 1 545 ? -33.693 -9.436 -4.956 1.00 19.20 ? 545 ALA A CA 1 ATOM 4314 C C . ALA A 1 545 ? -34.620 -9.130 -3.799 1.00 19.82 ? 545 ALA A C 1 ATOM 4315 O O . ALA A 1 545 ? -34.939 -10.015 -2.996 1.00 19.88 ? 545 ALA A O 1 ATOM 4316 C CB . ALA A 1 545 ? -33.574 -10.942 -5.201 1.00 20.01 ? 545 ALA A CB 1 ATOM 4317 N N . THR A 1 546 ? -35.017 -7.870 -3.688 1.00 19.04 ? 546 THR A N 1 ATOM 4318 C CA . THR A 1 546 ? -36.021 -7.462 -2.677 1.00 19.37 ? 546 THR A CA 1 ATOM 4319 C C . THR A 1 546 ? -37.143 -6.664 -3.315 1.00 17.52 ? 546 THR A C 1 ATOM 4320 O O . THR A 1 546 ? -36.971 -6.053 -4.371 1.00 14.83 ? 546 THR A O 1 ATOM 4321 C CB . THR A 1 546 ? -35.420 -6.625 -1.515 1.00 20.34 ? 546 THR A CB 1 ATOM 4322 O OG1 . THR A 1 546 ? -35.103 -5.289 -1.953 1.00 22.50 ? 546 THR A OG1 1 ATOM 4323 C CG2 . THR A 1 546 ? -34.156 -7.256 -0.958 1.00 20.83 ? 546 THR A CG2 1 ATOM 4324 N N . TRP A 1 547 ? -38.312 -6.639 -2.670 1.00 17.18 ? 547 TRP A N 1 ATOM 4325 C CA . TRP A 1 547 ? -39.344 -5.770 -3.180 1.00 17.98 ? 547 TRP A CA 1 ATOM 4326 C C . TRP A 1 547 ? -38.965 -4.279 -3.155 1.00 18.29 ? 547 TRP A C 1 ATOM 4327 O O . TRP A 1 547 ? -39.412 -3.536 -4.027 1.00 18.06 ? 547 TRP A O 1 ATOM 4328 C CB . TRP A 1 547 ? -40.660 -6.014 -2.445 1.00 17.63 ? 547 TRP A CB 1 ATOM 4329 C CG . TRP A 1 547 ? -41.162 -7.377 -2.750 1.00 17.16 ? 547 TRP A CG 1 ATOM 4330 C CD1 . TRP A 1 547 ? -40.832 -8.547 -2.112 1.00 20.03 ? 547 TRP A CD1 1 ATOM 4331 C CD2 . TRP A 1 547 ? -42.080 -7.727 -3.790 1.00 19.79 ? 547 TRP A CD2 1 ATOM 4332 N NE1 . TRP A 1 547 ? -41.526 -9.604 -2.682 1.00 19.64 ? 547 TRP A NE1 1 ATOM 4333 C CE2 . TRP A 1 547 ? -42.280 -9.124 -3.723 1.00 19.83 ? 547 TRP A CE2 1 ATOM 4334 C CE3 . TRP A 1 547 ? -42.754 -6.992 -4.782 1.00 18.09 ? 547 TRP A CE3 1 ATOM 4335 C CZ2 . TRP A 1 547 ? -43.125 -9.801 -4.611 1.00 20.87 ? 547 TRP A CZ2 1 ATOM 4336 C CZ3 . TRP A 1 547 ? -43.593 -7.672 -5.669 1.00 18.37 ? 547 TRP A CZ3 1 ATOM 4337 C CH2 . TRP A 1 547 ? -43.774 -9.059 -5.571 1.00 17.47 ? 547 TRP A CH2 1 ATOM 4338 N N . ASP A 1 548 ? -38.176 -3.843 -2.165 1.00 18.57 ? 548 ASP A N 1 ATOM 4339 C CA . ASP A 1 548 ? -37.714 -2.466 -2.120 1.00 19.30 ? 548 ASP A CA 1 ATOM 4340 C C . ASP A 1 548 ? -36.914 -2.147 -3.394 1.00 19.23 ? 548 ASP A C 1 ATOM 4341 O O . ASP A 1 548 ? -37.183 -1.121 -4.036 1.00 18.42 ? 548 ASP A O 1 ATOM 4342 C CB . ASP A 1 548 ? -36.830 -2.185 -0.909 1.00 20.30 ? 548 ASP A CB 1 ATOM 4343 C CG . ASP A 1 548 ? -37.618 -1.879 0.358 1.00 23.45 ? 548 ASP A CG 1 ATOM 4344 O OD1 . ASP A 1 548 ? -38.784 -1.389 0.319 1.00 24.61 ? 548 ASP A OD1 1 ATOM 4345 O OD2 . ASP A 1 548 ? -37.027 -2.116 1.417 1.00 27.16 ? 548 ASP A OD2 1 ATOM 4346 N N . ASP A 1 549 ? -35.982 -3.027 -3.781 1.00 18.46 ? 549 ASP A N 1 ATOM 4347 C CA . ASP A 1 549 ? -35.177 -2.774 -4.994 1.00 18.10 ? 549 ASP A CA 1 ATOM 4348 C C . ASP A 1 549 ? -36.035 -2.664 -6.253 1.00 17.94 ? 549 ASP A C 1 ATOM 4349 O O . ASP A 1 549 ? -35.763 -1.843 -7.133 1.00 17.36 ? 549 ASP A O 1 ATOM 4350 C CB . ASP A 1 549 ? -34.087 -3.810 -5.191 1.00 18.60 ? 549 ASP A CB 1 ATOM 4351 C CG . ASP A 1 549 ? -32.987 -3.714 -4.137 1.00 22.48 ? 549 ASP A CG 1 ATOM 4352 O OD1 . ASP A 1 549 ? -31.850 -3.361 -4.488 1.00 23.69 ? 549 ASP A OD1 1 ATOM 4353 O OD2 . ASP A 1 549 ? -33.260 -4.051 -2.957 1.00 28.93 ? 549 ASP A OD2 1 ATOM 4354 N N . LEU A 1 550 ? -37.088 -3.474 -6.340 1.00 17.34 ? 550 LEU A N 1 ATOM 4355 C CA . LEU A 1 550 ? -37.999 -3.390 -7.469 1.00 17.37 ? 550 LEU A CA 1 ATOM 4356 C C . LEU A 1 550 ? -38.681 -2.011 -7.534 1.00 17.85 ? 550 LEU A C 1 ATOM 4357 O O . LEU A 1 550 ? -38.670 -1.356 -8.583 1.00 17.44 ? 550 LEU A O 1 ATOM 4358 C CB . LEU A 1 550 ? -39.040 -4.517 -7.363 1.00 16.93 ? 550 LEU A CB 1 ATOM 4359 C CG . LEU A 1 550 ? -40.288 -4.414 -8.266 1.00 20.12 ? 550 LEU A CG 1 ATOM 4360 C CD1 . LEU A 1 550 ? -39.874 -4.688 -9.690 1.00 21.97 ? 550 LEU A CD1 1 ATOM 4361 C CD2 . LEU A 1 550 ? -41.277 -5.407 -7.821 1.00 20.68 ? 550 LEU A CD2 1 ATOM 4362 N N . ARG A 1 551 ? -39.275 -1.576 -6.410 1.00 17.74 ? 551 ARG A N 1 ATOM 4363 C CA . ARG A 1 551 ? -39.845 -0.221 -6.307 1.00 17.83 ? 551 ARG A CA 1 ATOM 4364 C C . ARG A 1 551 ? -38.826 0.909 -6.636 1.00 17.79 ? 551 ARG A C 1 ATOM 4365 O O . ARG A 1 551 ? -39.126 1.862 -7.362 1.00 18.70 ? 551 ARG A O 1 ATOM 4366 C CB . ARG A 1 551 ? -40.413 -0.047 -4.904 1.00 18.25 ? 551 ARG A CB 1 ATOM 4367 C CG . ARG A 1 551 ? -41.718 -0.862 -4.739 1.00 18.13 ? 551 ARG A CG 1 ATOM 4368 C CD . ARG A 1 551 ? -42.400 -0.570 -3.389 1.00 22.69 ? 551 ARG A CD 1 ATOM 4369 N NE . ARG A 1 551 ? -41.624 -1.053 -2.243 1.00 24.90 ? 551 ARG A NE 1 ATOM 4370 C CZ . ARG A 1 551 ? -41.827 -2.222 -1.631 1.00 26.18 ? 551 ARG A CZ 1 ATOM 4371 N NH1 . ARG A 1 551 ? -42.745 -3.074 -2.068 1.00 23.71 ? 551 ARG A NH1 1 ATOM 4372 N NH2 . ARG A 1 551 ? -41.093 -2.558 -0.587 1.00 23.74 ? 551 ARG A NH2 1 ATOM 4373 N N . TRP A 1 552 ? -37.626 0.784 -6.107 1.00 16.74 ? 552 TRP A N 1 ATOM 4374 C CA . TRP A 1 552 ? -36.626 1.853 -6.255 1.00 16.51 ? 552 TRP A CA 1 ATOM 4375 C C . TRP A 1 552 ? -36.091 1.975 -7.659 1.00 16.35 ? 552 TRP A C 1 ATOM 4376 O O . TRP A 1 552 ? -35.422 2.977 -8.006 1.00 17.14 ? 552 TRP A O 1 ATOM 4377 C CB . TRP A 1 552 ? -35.476 1.586 -5.318 1.00 17.87 ? 552 TRP A CB 1 ATOM 4378 C CG . TRP A 1 552 ? -35.889 1.719 -3.884 1.00 19.61 ? 552 TRP A CG 1 ATOM 4379 C CD1 . TRP A 1 552 ? -36.989 2.366 -3.392 1.00 19.64 ? 552 TRP A CD1 1 ATOM 4380 C CD2 . TRP A 1 552 ? -35.177 1.204 -2.764 1.00 20.91 ? 552 TRP A CD2 1 ATOM 4381 N NE1 . TRP A 1 552 ? -37.022 2.245 -2.023 1.00 21.16 ? 552 TRP A NE1 1 ATOM 4382 C CE2 . TRP A 1 552 ? -35.902 1.547 -1.619 1.00 22.09 ? 552 TRP A CE2 1 ATOM 4383 C CE3 . TRP A 1 552 ? -34.003 0.448 -2.627 1.00 21.36 ? 552 TRP A CE3 1 ATOM 4384 C CZ2 . TRP A 1 552 ? -35.481 1.173 -0.331 1.00 21.45 ? 552 TRP A CZ2 1 ATOM 4385 C CZ3 . TRP A 1 552 ? -33.591 0.061 -1.345 1.00 21.66 ? 552 TRP A CZ3 1 ATOM 4386 C CH2 . TRP A 1 552 ? -34.336 0.429 -0.224 1.00 21.15 ? 552 TRP A CH2 1 ATOM 4387 N N . SER A 1 553 ? -36.311 0.936 -8.458 1.00 15.49 ? 553 SER A N 1 ATOM 4388 C CA . SER A 1 553 ? -35.845 0.950 -9.843 1.00 15.99 ? 553 SER A CA 1 ATOM 4389 C C . SER A 1 553 ? -36.523 2.012 -10.699 1.00 15.79 ? 553 SER A C 1 ATOM 4390 O O . SER A 1 553 ? -35.885 2.557 -11.596 1.00 15.86 ? 553 SER A O 1 ATOM 4391 C CB . SER A 1 553 ? -35.933 -0.428 -10.525 1.00 15.65 ? 553 SER A CB 1 ATOM 4392 O OG . SER A 1 553 ? -37.298 -0.762 -10.836 1.00 15.75 ? 553 SER A OG 1 ATOM 4393 N N . ILE A 1 554 ? -37.812 2.290 -10.466 1.00 16.22 ? 554 ILE A N 1 ATOM 4394 C CA . ILE A 1 554 ? -38.482 3.201 -11.366 1.00 16.08 ? 554 ILE A CA 1 ATOM 4395 C C . ILE A 1 554 ? -37.932 4.616 -11.282 1.00 15.85 ? 554 ILE A C 1 ATOM 4396 O O . ILE A 1 554 ? -37.662 5.196 -12.315 1.00 16.77 ? 554 ILE A O 1 ATOM 4397 C CB . ILE A 1 554 ? -40.026 3.152 -11.246 1.00 17.09 ? 554 ILE A CB 1 ATOM 4398 C CG1 . ILE A 1 554 ? -40.487 1.747 -11.681 1.00 19.86 ? 554 ILE A CG1 1 ATOM 4399 C CG2 . ILE A 1 554 ? -40.658 4.201 -12.170 1.00 17.58 ? 554 ILE A CG2 1 ATOM 4400 C CD1 . ILE A 1 554 ? -41.930 1.387 -11.330 1.00 17.98 ? 554 ILE A CD1 1 ATOM 4401 N N . PRO A 1 555 ? -37.823 5.204 -10.075 1.00 15.00 ? 555 PRO A N 1 ATOM 4402 C CA . PRO A 1 555 ? -37.228 6.545 -10.111 1.00 16.73 ? 555 PRO A CA 1 ATOM 4403 C C . PRO A 1 555 ? -35.830 6.544 -10.726 1.00 15.44 ? 555 PRO A C 1 ATOM 4404 O O . PRO A 1 555 ? -35.483 7.517 -11.393 1.00 15.89 ? 555 PRO A O 1 ATOM 4405 C CB . PRO A 1 555 ? -37.177 6.978 -8.633 1.00 16.38 ? 555 PRO A CB 1 ATOM 4406 C CG . PRO A 1 555 ? -38.230 6.175 -7.956 1.00 14.80 ? 555 PRO A CG 1 ATOM 4407 C CD . PRO A 1 555 ? -38.298 4.848 -8.721 1.00 16.27 ? 555 PRO A CD 1 ATOM 4408 N N . GLY A 1 556 ? -35.068 5.460 -10.558 1.00 15.94 ? 556 GLY A N 1 ATOM 4409 C CA . GLY A 1 556 ? -33.668 5.418 -11.117 1.00 14.00 ? 556 GLY A CA 1 ATOM 4410 C C . GLY A 1 556 ? -33.706 5.450 -12.640 1.00 15.70 ? 556 GLY A C 1 ATOM 4411 O O . GLY A 1 556 ? -32.901 6.130 -13.280 1.00 16.85 ? 556 GLY A O 1 ATOM 4412 N N . VAL A 1 557 ? -34.688 4.756 -13.229 1.00 15.34 ? 557 VAL A N 1 ATOM 4413 C CA . VAL A 1 557 ? -34.840 4.729 -14.674 1.00 15.03 ? 557 VAL A CA 1 ATOM 4414 C C . VAL A 1 557 ? -35.281 6.104 -15.190 1.00 15.31 ? 557 VAL A C 1 ATOM 4415 O O . VAL A 1 557 ? -34.748 6.609 -16.196 1.00 14.67 ? 557 VAL A O 1 ATOM 4416 C CB . VAL A 1 557 ? -35.828 3.606 -15.105 1.00 15.35 ? 557 VAL A CB 1 ATOM 4417 C CG1 . VAL A 1 557 ? -36.344 3.848 -16.504 1.00 16.41 ? 557 VAL A CG1 1 ATOM 4418 C CG2 . VAL A 1 557 ? -35.117 2.220 -15.013 1.00 13.54 ? 557 VAL A CG2 1 ATOM 4419 N N . LEU A 1 558 ? -36.250 6.734 -14.497 1.00 14.47 ? 558 LEU A N 1 ATOM 4420 C CA . LEU A 1 558 ? -36.731 8.061 -14.906 1.00 14.99 ? 558 LEU A CA 1 ATOM 4421 C C . LEU A 1 558 ? -35.614 9.101 -14.829 1.00 13.91 ? 558 LEU A C 1 ATOM 4422 O O . LEU A 1 558 ? -35.444 9.946 -15.712 1.00 13.86 ? 558 LEU A O 1 ATOM 4423 C CB . LEU A 1 558 ? -37.898 8.496 -14.011 1.00 13.81 ? 558 LEU A CB 1 ATOM 4424 C CG . LEU A 1 558 ? -39.132 7.606 -14.204 1.00 14.52 ? 558 LEU A CG 1 ATOM 4425 C CD1 . LEU A 1 558 ? -40.159 8.029 -13.222 1.00 14.75 ? 558 LEU A CD1 1 ATOM 4426 C CD2 . LEU A 1 558 ? -39.634 7.660 -15.650 1.00 15.29 ? 558 LEU A CD2 1 ATOM 4427 N N . GLU A 1 559 ? -34.859 9.068 -13.750 1.00 14.00 ? 559 GLU A N 1 ATOM 4428 C CA . GLU A 1 559 ? -33.750 10.007 -13.611 1.00 14.64 ? 559 GLU A CA 1 ATOM 4429 C C . GLU A 1 559 ? -32.746 9.892 -14.734 1.00 14.09 ? 559 GLU A C 1 ATOM 4430 O O . GLU A 1 559 ? -32.327 10.906 -15.269 1.00 13.58 ? 559 GLU A O 1 ATOM 4431 C CB . GLU A 1 559 ? -33.070 9.836 -12.249 1.00 14.88 ? 559 GLU A CB 1 ATOM 4432 C CG . GLU A 1 559 ? -33.988 10.363 -11.111 1.00 15.30 ? 559 GLU A CG 1 ATOM 4433 C CD . GLU A 1 559 ? -33.677 9.724 -9.741 1.00 22.35 ? 559 GLU A CD 1 ATOM 4434 O OE1 . GLU A 1 559 ? -32.705 8.899 -9.638 1.00 20.87 ? 559 GLU A OE1 1 ATOM 4435 O OE2 . GLU A 1 559 ? -34.403 10.067 -8.767 1.00 21.58 ? 559 GLU A OE2 1 ATOM 4436 N N . PHE A 1 560 ? -32.326 8.684 -15.083 1.00 14.03 ? 560 PHE A N 1 ATOM 4437 C CA . PHE A 1 560 ? -31.358 8.570 -16.195 1.00 13.80 ? 560 PHE A CA 1 ATOM 4438 C C . PHE A 1 560 ? -31.872 9.032 -17.528 1.00 14.49 ? 560 PHE A C 1 ATOM 4439 O O . PHE A 1 560 ? -31.090 9.474 -18.356 1.00 13.33 ? 560 PHE A O 1 ATOM 4440 C CB . PHE A 1 560 ? -30.710 7.207 -16.247 1.00 14.04 ? 560 PHE A CB 1 ATOM 4441 C CG . PHE A 1 560 ? -29.584 7.128 -15.309 1.00 15.31 ? 560 PHE A CG 1 ATOM 4442 C CD1 . PHE A 1 560 ? -29.807 6.754 -13.994 1.00 16.47 ? 560 PHE A CD1 1 ATOM 4443 C CD2 . PHE A 1 560 ? -28.303 7.549 -15.714 1.00 16.42 ? 560 PHE A CD2 1 ATOM 4444 C CE1 . PHE A 1 560 ? -28.749 6.760 -13.073 1.00 21.91 ? 560 PHE A CE1 1 ATOM 4445 C CE2 . PHE A 1 560 ? -27.254 7.558 -14.798 1.00 18.46 ? 560 PHE A CE2 1 ATOM 4446 C CZ . PHE A 1 560 ? -27.495 7.150 -13.490 1.00 16.58 ? 560 PHE A CZ 1 ATOM 4447 N N . ASN A 1 561 ? -33.193 8.951 -17.730 1.00 13.85 ? 561 ASN A N 1 ATOM 4448 C CA . ASN A 1 561 ? -33.808 9.549 -18.921 1.00 13.95 ? 561 ASN A CA 1 ATOM 4449 C C . ASN A 1 561 ? -33.664 11.088 -18.935 1.00 14.71 ? 561 ASN A C 1 ATOM 4450 O O . ASN A 1 561 ? -33.340 11.691 -19.971 1.00 15.73 ? 561 ASN A O 1 ATOM 4451 C CB . ASN A 1 561 ? -35.276 9.066 -19.071 1.00 13.48 ? 561 ASN A CB 1 ATOM 4452 C CG . ASN A 1 561 ? -35.356 7.773 -19.833 1.00 12.36 ? 561 ASN A CG 1 ATOM 4453 O OD1 . ASN A 1 561 ? -35.651 7.791 -21.017 1.00 14.29 ? 561 ASN A OD1 1 ATOM 4454 N ND2 . ASN A 1 561 ? -35.023 6.636 -19.177 1.00 13.59 ? 561 ASN A ND2 1 ATOM 4455 N N . LEU A 1 562 ? -33.855 11.736 -17.783 1.00 15.93 ? 562 LEU A N 1 ATOM 4456 C CA . LEU A 1 562 ? -33.486 13.158 -17.634 1.00 15.25 ? 562 LEU A CA 1 ATOM 4457 C C . LEU A 1 562 ? -32.016 13.428 -17.977 1.00 15.58 ? 562 LEU A C 1 ATOM 4458 O O . LEU A 1 562 ? -31.707 14.436 -18.570 1.00 15.67 ? 562 LEU A O 1 ATOM 4459 C CB . LEU A 1 562 ? -33.727 13.648 -16.203 1.00 15.30 ? 562 LEU A CB 1 ATOM 4460 C CG . LEU A 1 562 ? -35.067 13.560 -15.490 1.00 18.53 ? 562 LEU A CG 1 ATOM 4461 C CD1 . LEU A 1 562 ? -34.877 14.334 -14.157 1.00 18.96 ? 562 LEU A CD1 1 ATOM 4462 C CD2 . LEU A 1 562 ? -36.216 14.149 -16.371 1.00 16.35 ? 562 LEU A CD2 1 ATOM 4463 N N . PHE A 1 563 ? -31.113 12.528 -17.608 1.00 15.52 ? 563 PHE A N 1 ATOM 4464 C CA . PHE A 1 563 ? -29.656 12.743 -17.831 1.00 15.62 ? 563 PHE A CA 1 ATOM 4465 C C . PHE A 1 563 ? -29.238 12.392 -19.259 1.00 15.98 ? 563 PHE A C 1 ATOM 4466 O O . PHE A 1 563 ? -28.037 12.436 -19.616 1.00 17.07 ? 563 PHE A O 1 ATOM 4467 C CB . PHE A 1 563 ? -28.864 11.865 -16.812 1.00 14.68 ? 563 PHE A CB 1 ATOM 4468 C CG . PHE A 1 563 ? -29.240 12.106 -15.364 1.00 14.29 ? 563 PHE A CG 1 ATOM 4469 C CD1 . PHE A 1 563 ? -29.665 13.379 -14.932 1.00 13.92 ? 563 PHE A CD1 1 ATOM 4470 C CD2 . PHE A 1 563 ? -29.144 11.063 -14.428 1.00 15.81 ? 563 PHE A CD2 1 ATOM 4471 C CE1 . PHE A 1 563 ? -30.007 13.601 -13.627 1.00 13.59 ? 563 PHE A CE1 1 ATOM 4472 C CE2 . PHE A 1 563 ? -29.487 11.284 -13.092 1.00 17.66 ? 563 PHE A CE2 1 ATOM 4473 C CZ . PHE A 1 563 ? -29.919 12.559 -12.706 1.00 14.26 ? 563 PHE A CZ 1 ATOM 4474 N N . GLY A 1 564 ? -30.208 12.017 -20.095 1.00 15.37 ? 564 GLY A N 1 ATOM 4475 C CA . GLY A 1 564 ? -29.905 11.657 -21.481 1.00 15.22 ? 564 GLY A CA 1 ATOM 4476 C C . GLY A 1 564 ? -29.244 10.308 -21.663 1.00 14.40 ? 564 GLY A C 1 ATOM 4477 O O . GLY A 1 564 ? -28.486 10.099 -22.626 1.00 15.07 ? 564 GLY A O 1 ATOM 4478 N N . ILE A 1 565 ? -29.489 9.394 -20.723 1.00 12.99 ? 565 ILE A N 1 ATOM 4479 C CA . ILE A 1 565 ? -29.118 7.984 -20.854 1.00 14.01 ? 565 ILE A CA 1 ATOM 4480 C C . ILE A 1 565 ? -30.443 7.189 -20.824 1.00 14.52 ? 565 ILE A C 1 ATOM 4481 O O . ILE A 1 565 ? -30.763 6.512 -19.846 1.00 13.31 ? 565 ILE A O 1 ATOM 4482 C CB . ILE A 1 565 ? -28.237 7.554 -19.719 1.00 15.39 ? 565 ILE A CB 1 ATOM 4483 C CG1 . ILE A 1 565 ? -27.091 8.579 -19.612 1.00 16.26 ? 565 ILE A CG1 1 ATOM 4484 C CG2 . ILE A 1 565 ? -27.714 6.117 -19.956 1.00 18.91 ? 565 ILE A CG2 1 ATOM 4485 C CD1 . ILE A 1 565 ? -26.125 8.423 -18.416 1.00 21.30 ? 565 ILE A CD1 1 ATOM 4486 N N . PRO A 1 566 ? -31.205 7.278 -21.911 1.00 14.91 ? 566 PRO A N 1 ATOM 4487 C CA . PRO A 1 566 ? -32.523 6.670 -21.834 1.00 15.05 ? 566 PRO A CA 1 ATOM 4488 C C . PRO A 1 566 ? -32.485 5.139 -21.820 1.00 15.06 ? 566 PRO A C 1 ATOM 4489 O O . PRO A 1 566 ? -33.413 4.538 -21.333 1.00 14.08 ? 566 PRO A O 1 ATOM 4490 C CB . PRO A 1 566 ? -33.215 7.165 -23.098 1.00 15.19 ? 566 PRO A CB 1 ATOM 4491 C CG . PRO A 1 566 ? -32.049 7.440 -24.070 1.00 14.06 ? 566 PRO A CG 1 ATOM 4492 C CD . PRO A 1 566 ? -30.951 7.958 -23.193 1.00 15.10 ? 566 PRO A CD 1 ATOM 4493 N N . MET A 1 567 ? -31.437 4.530 -22.380 1.00 15.10 ? 567 MET A N 1 ATOM 4494 C CA . MET A 1 567 ? -31.352 3.087 -22.328 1.00 16.00 ? 567 MET A CA 1 ATOM 4495 C C . MET A 1 567 ? -30.769 2.689 -20.964 1.00 15.06 ? 567 MET A C 1 ATOM 4496 O O . MET A 1 567 ? -29.545 2.610 -20.795 1.00 14.79 ? 567 MET A O 1 ATOM 4497 C CB . MET A 1 567 ? -30.547 2.534 -23.502 1.00 14.44 ? 567 MET A CB 1 ATOM 4498 C CG . MET A 1 567 ? -30.630 1.041 -23.516 1.00 17.82 ? 567 MET A CG 1 ATOM 4499 S SD . MET A 1 567 ? -30.001 0.246 -24.990 1.00 22.86 ? 567 MET A SD 1 ATOM 4500 C CE . MET A 1 567 ? -31.528 0.077 -25.929 1.00 20.50 ? 567 MET A CE 1 ATOM 4501 N N . VAL A 1 568 ? -31.653 2.463 -19.982 1.00 12.72 ? 568 VAL A N 1 ATOM 4502 C CA . VAL A 1 568 ? -31.209 2.228 -18.619 1.00 13.77 ? 568 VAL A CA 1 ATOM 4503 C C . VAL A 1 568 ? -32.208 1.265 -18.022 1.00 15.21 ? 568 VAL A C 1 ATOM 4504 O O . VAL A 1 568 ? -33.392 1.279 -18.390 1.00 14.66 ? 568 VAL A O 1 ATOM 4505 C CB . VAL A 1 568 ? -31.132 3.580 -17.795 1.00 12.93 ? 568 VAL A CB 1 ATOM 4506 C CG1 . VAL A 1 568 ? -32.471 4.366 -17.860 1.00 12.45 ? 568 VAL A CG1 1 ATOM 4507 C CG2 . VAL A 1 568 ? -30.656 3.365 -16.325 1.00 13.81 ? 568 VAL A CG2 1 ATOM 4508 N N . GLY A 1 569 ? -31.734 0.444 -17.096 1.00 16.30 ? 569 GLY A N 1 ATOM 4509 C CA . GLY A 1 569 ? -32.610 -0.475 -16.382 1.00 16.98 ? 569 GLY A CA 1 ATOM 4510 C C . GLY A 1 569 ? -31.830 -1.095 -15.242 1.00 17.98 ? 569 GLY A C 1 ATOM 4511 O O . GLY A 1 569 ? -30.607 -0.968 -15.209 1.00 17.95 ? 569 GLY A O 1 ATOM 4512 N N . PRO A 1 570 ? -32.513 -1.747 -14.295 1.00 17.62 ? 570 PRO A N 1 ATOM 4513 C CA . PRO A 1 570 ? -31.791 -2.472 -13.261 1.00 18.53 ? 570 PRO A CA 1 ATOM 4514 C C . PRO A 1 570 ? -31.426 -3.919 -13.722 1.00 19.38 ? 570 PRO A C 1 ATOM 4515 O O . PRO A 1 570 ? -31.699 -4.324 -14.882 1.00 19.98 ? 570 PRO A O 1 ATOM 4516 C CB . PRO A 1 570 ? -32.838 -2.564 -12.142 1.00 18.05 ? 570 PRO A CB 1 ATOM 4517 C CG . PRO A 1 570 ? -34.149 -2.763 -12.914 1.00 18.84 ? 570 PRO A CG 1 ATOM 4518 C CD . PRO A 1 570 ? -33.974 -1.849 -14.131 1.00 19.37 ? 570 PRO A CD 1 ATOM 4519 N N . ASP A 1 571 ? -30.856 -4.714 -12.809 1.00 19.68 ? 571 ASP A N 1 ATOM 4520 C CA . ASP A 1 571 ? -30.730 -6.171 -13.027 1.00 18.94 ? 571 ASP A CA 1 ATOM 4521 C C . ASP A 1 571 ? -32.106 -6.740 -12.661 1.00 19.05 ? 571 ASP A C 1 ATOM 4522 O O . ASP A 1 571 ? -32.487 -6.740 -11.484 1.00 19.12 ? 571 ASP A O 1 ATOM 4523 C CB . ASP A 1 571 ? -29.658 -6.756 -12.116 1.00 18.48 ? 571 ASP A CB 1 ATOM 4524 C CG . ASP A 1 571 ? -28.230 -6.399 -12.561 1.00 19.47 ? 571 ASP A CG 1 ATOM 4525 O OD1 . ASP A 1 571 ? -28.039 -5.950 -13.710 1.00 23.44 ? 571 ASP A OD1 1 ATOM 4526 O OD2 . ASP A 1 571 ? -27.254 -6.553 -11.765 1.00 24.51 ? 571 ASP A OD2 1 ATOM 4527 N N . ILE A 1 572 ? -32.867 -7.183 -13.658 1.00 18.78 ? 572 ILE A N 1 ATOM 4528 C CA . ILE A 1 572 ? -34.220 -7.640 -13.416 1.00 18.12 ? 572 ILE A CA 1 ATOM 4529 C C . ILE A 1 572 ? -34.091 -8.913 -12.548 1.00 18.73 ? 572 ILE A C 1 ATOM 4530 O O . ILE A 1 572 ? -33.206 -9.767 -12.795 1.00 19.18 ? 572 ILE A O 1 ATOM 4531 C CB . ILE A 1 572 ? -34.973 -7.982 -14.724 1.00 18.54 ? 572 ILE A CB 1 ATOM 4532 C CG1 . ILE A 1 572 ? -35.264 -6.703 -15.532 1.00 17.71 ? 572 ILE A CG1 1 ATOM 4533 C CG2 . ILE A 1 572 ? -36.290 -8.748 -14.433 1.00 19.11 ? 572 ILE A CG2 1 ATOM 4534 C CD1 . ILE A 1 572 ? -35.817 -6.986 -16.942 1.00 18.73 ? 572 ILE A CD1 1 ATOM 4535 N N . CYS A 1 573 ? -34.931 -8.985 -11.523 1.00 18.74 ? 573 CYS A N 1 ATOM 4536 C CA . CYS A 1 573 ? -34.987 -10.097 -10.558 1.00 19.15 ? 573 CYS A CA 1 ATOM 4537 C C . CYS A 1 573 ? -34.002 -9.961 -9.416 1.00 19.96 ? 573 CYS A C 1 ATOM 4538 O O . CYS A 1 573 ? -34.189 -10.569 -8.378 1.00 20.32 ? 573 CYS A O 1 ATOM 4539 C CB . CYS A 1 573 ? -34.913 -11.475 -11.247 1.00 20.44 ? 573 CYS A CB 1 ATOM 4540 S SG . CYS A 1 573 ? -36.483 -11.729 -12.177 1.00 22.80 ? 573 CYS A SG 1 ATOM 4541 N N . GLY A 1 574 ? -32.950 -9.167 -9.604 1.00 18.41 ? 574 GLY A N 1 ATOM 4542 C CA . GLY A 1 574 ? -32.123 -8.778 -8.487 1.00 19.27 ? 574 GLY A CA 1 ATOM 4543 C C . GLY A 1 574 ? -30.777 -9.450 -8.649 1.00 19.40 ? 574 GLY A C 1 ATOM 4544 O O . GLY A 1 574 ? -30.698 -10.658 -8.772 1.00 21.08 ? 574 GLY A O 1 ATOM 4545 N N . PHE A 1 575 ? -29.733 -8.664 -8.625 1.00 19.05 ? 575 PHE A N 1 ATOM 4546 C CA . PHE A 1 575 ? -28.403 -9.204 -8.721 1.00 19.32 ? 575 PHE A CA 1 ATOM 4547 C C . PHE A 1 575 ? -28.083 -10.106 -7.503 1.00 19.03 ? 575 PHE A C 1 ATOM 4548 O O . PHE A 1 575 ? -28.019 -11.324 -7.647 1.00 19.99 ? 575 PHE A O 1 ATOM 4549 C CB . PHE A 1 575 ? -27.418 -8.073 -8.866 1.00 18.62 ? 575 PHE A CB 1 ATOM 4550 C CG . PHE A 1 575 ? -26.018 -8.519 -9.033 1.00 20.40 ? 575 PHE A CG 1 ATOM 4551 C CD1 . PHE A 1 575 ? -25.608 -9.096 -10.228 1.00 18.81 ? 575 PHE A CD1 1 ATOM 4552 C CD2 . PHE A 1 575 ? -25.089 -8.349 -7.990 1.00 20.84 ? 575 PHE A CD2 1 ATOM 4553 C CE1 . PHE A 1 575 ? -24.295 -9.497 -10.392 1.00 18.62 ? 575 PHE A CE1 1 ATOM 4554 C CE2 . PHE A 1 575 ? -23.756 -8.761 -8.145 1.00 22.47 ? 575 PHE A CE2 1 ATOM 4555 C CZ . PHE A 1 575 ? -23.360 -9.327 -9.358 1.00 21.21 ? 575 PHE A CZ 1 ATOM 4556 N N . ALA A 1 576 ? -27.885 -9.520 -6.319 1.00 19.55 ? 576 ALA A N 1 ATOM 4557 C CA . ALA A 1 576 ? -27.583 -10.302 -5.096 1.00 20.45 ? 576 ALA A CA 1 ATOM 4558 C C . ALA A 1 576 ? -28.810 -11.036 -4.554 1.00 20.81 ? 576 ALA A C 1 ATOM 4559 O O . ALA A 1 576 ? -29.913 -10.511 -4.632 1.00 21.27 ? 576 ALA A O 1 ATOM 4560 C CB . ALA A 1 576 ? -26.987 -9.366 -3.999 1.00 20.46 ? 576 ALA A CB 1 ATOM 4561 N N . LEU A 1 577 ? -28.602 -12.242 -4.008 1.00 20.83 ? 577 LEU A N 1 ATOM 4562 C CA . LEU A 1 577 ? -29.638 -13.047 -3.341 1.00 22.01 ? 577 LEU A CA 1 ATOM 4563 C C . LEU A 1 577 ? -30.406 -13.917 -4.336 1.00 21.94 ? 577 LEU A C 1 ATOM 4564 O O . LEU A 1 577 ? -30.486 -13.590 -5.519 1.00 21.25 ? 577 LEU A O 1 ATOM 4565 C CB . LEU A 1 577 ? -30.607 -12.181 -2.510 1.00 21.60 ? 577 LEU A CB 1 ATOM 4566 C CG . LEU A 1 577 ? -30.236 -11.837 -1.081 1.00 25.34 ? 577 LEU A CG 1 ATOM 4567 C CD1 . LEU A 1 577 ? -28.726 -11.744 -0.842 1.00 25.22 ? 577 LEU A CD1 1 ATOM 4568 C CD2 . LEU A 1 577 ? -30.956 -10.631 -0.627 1.00 24.34 ? 577 LEU A CD2 1 ATOM 4569 N N . ASP A 1 578 ? -30.919 -15.044 -3.838 1.00 22.34 ? 578 ASP A N 1 ATOM 4570 C CA . ASP A 1 578 ? -31.867 -15.889 -4.540 1.00 23.87 ? 578 ASP A CA 1 ATOM 4571 C C . ASP A 1 578 ? -33.171 -15.117 -4.659 1.00 23.66 ? 578 ASP A C 1 ATOM 4572 O O . ASP A 1 578 ? -33.629 -14.535 -3.672 1.00 24.08 ? 578 ASP A O 1 ATOM 4573 C CB . ASP A 1 578 ? -32.167 -17.153 -3.729 1.00 23.87 ? 578 ASP A CB 1 ATOM 4574 C CG . ASP A 1 578 ? -30.951 -18.036 -3.534 1.00 27.50 ? 578 ASP A CG 1 ATOM 4575 O OD1 . ASP A 1 578 ? -29.879 -17.772 -4.121 1.00 26.43 ? 578 ASP A OD1 1 ATOM 4576 O OD2 . ASP A 1 578 ? -31.079 -19.016 -2.777 1.00 30.13 ? 578 ASP A OD2 1 ATOM 4577 N N . THR A 1 579 ? -33.772 -15.120 -5.845 1.00 22.74 ? 579 THR A N 1 ATOM 4578 C CA . THR A 1 579 ? -34.978 -14.343 -6.049 1.00 21.80 ? 579 THR A CA 1 ATOM 4579 C C . THR A 1 579 ? -36.222 -15.202 -5.778 1.00 22.30 ? 579 THR A C 1 ATOM 4580 O O . THR A 1 579 ? -36.317 -16.313 -6.285 1.00 22.10 ? 579 THR A O 1 ATOM 4581 C CB . THR A 1 579 ? -34.990 -13.677 -7.461 1.00 21.42 ? 579 THR A CB 1 ATOM 4582 O OG1 . THR A 1 579 ? -35.948 -12.620 -7.498 1.00 22.83 ? 579 THR A OG1 1 ATOM 4583 C CG2 . THR A 1 579 ? -35.292 -14.675 -8.598 1.00 20.77 ? 579 THR A CG2 1 ATOM 4584 N N . PRO A 1 580 ? -37.150 -14.706 -4.952 1.00 22.57 ? 580 PRO A N 1 ATOM 4585 C CA . PRO A 1 580 ? -38.420 -15.450 -4.847 1.00 23.02 ? 580 PRO A CA 1 ATOM 4586 C C . PRO A 1 580 ? -39.179 -15.458 -6.176 1.00 23.52 ? 580 PRO A C 1 ATOM 4587 O O . PRO A 1 580 ? -39.135 -14.476 -6.940 1.00 22.23 ? 580 PRO A O 1 ATOM 4588 C CB . PRO A 1 580 ? -39.239 -14.665 -3.814 1.00 23.46 ? 580 PRO A CB 1 ATOM 4589 C CG . PRO A 1 580 ? -38.435 -13.504 -3.384 1.00 23.83 ? 580 PRO A CG 1 ATOM 4590 C CD . PRO A 1 580 ? -37.103 -13.486 -4.122 1.00 23.26 ? 580 PRO A CD 1 ATOM 4591 N N . GLU A 1 581 ? -39.905 -16.538 -6.452 1.00 23.44 ? 581 GLU A N 1 ATOM 4592 C CA . GLU A 1 581 ? -40.675 -16.617 -7.689 1.00 23.24 ? 581 GLU A CA 1 ATOM 4593 C C . GLU A 1 581 ? -41.628 -15.415 -7.889 1.00 22.31 ? 581 GLU A C 1 ATOM 4594 O O . GLU A 1 581 ? -41.830 -14.939 -9.003 1.00 22.16 ? 581 GLU A O 1 ATOM 4595 C CB . GLU A 1 581 ? -41.489 -17.910 -7.718 1.00 22.80 ? 581 GLU A CB 1 ATOM 4596 C CG . GLU A 1 581 ? -42.135 -18.179 -9.034 1.00 23.64 ? 581 GLU A CG 1 ATOM 4597 C CD . GLU A 1 581 ? -43.515 -17.557 -9.164 1.00 25.91 ? 581 GLU A CD 1 ATOM 4598 O OE1 . GLU A 1 581 ? -44.114 -17.072 -8.162 1.00 27.47 ? 581 GLU A OE1 1 ATOM 4599 O OE2 . GLU A 1 581 ? -44.011 -17.552 -10.299 1.00 28.88 ? 581 GLU A OE2 1 ATOM 4600 N N . GLU A 1 582 ? -42.265 -14.962 -6.823 1.00 21.67 ? 582 GLU A N 1 ATOM 4601 C CA . GLU A 1 582 ? -43.301 -13.963 -6.992 1.00 21.50 ? 582 GLU A CA 1 ATOM 4602 C C . GLU A 1 582 ? -42.623 -12.643 -7.355 1.00 20.52 ? 582 GLU A C 1 ATOM 4603 O O . GLU A 1 582 ? -43.090 -11.906 -8.223 1.00 18.40 ? 582 GLU A O 1 ATOM 4604 C CB . GLU A 1 582 ? -44.126 -13.813 -5.731 1.00 21.80 ? 582 GLU A CB 1 ATOM 4605 C CG . GLU A 1 582 ? -45.230 -12.788 -5.898 1.00 23.38 ? 582 GLU A CG 1 ATOM 4606 C CD . GLU A 1 582 ? -45.807 -12.312 -4.581 1.00 28.72 ? 582 GLU A CD 1 ATOM 4607 O OE1 . GLU A 1 582 ? -45.467 -12.883 -3.503 1.00 32.01 ? 582 GLU A OE1 1 ATOM 4608 O OE2 . GLU A 1 582 ? -46.607 -11.354 -4.618 1.00 27.46 ? 582 GLU A OE2 1 ATOM 4609 N N . LEU A 1 583 ? -41.486 -12.383 -6.716 1.00 20.11 ? 583 LEU A N 1 ATOM 4610 C CA . LEU A 1 583 ? -40.788 -11.149 -6.960 1.00 19.10 ? 583 LEU A CA 1 ATOM 4611 C C . LEU A 1 583 ? -40.246 -11.190 -8.383 1.00 19.51 ? 583 LEU A C 1 ATOM 4612 O O . LEU A 1 583 ? -40.405 -10.231 -9.128 1.00 19.04 ? 583 LEU A O 1 ATOM 4613 C CB . LEU A 1 583 ? -39.673 -10.908 -5.927 1.00 19.06 ? 583 LEU A CB 1 ATOM 4614 C CG . LEU A 1 583 ? -38.663 -9.798 -6.275 1.00 18.86 ? 583 LEU A CG 1 ATOM 4615 C CD1 . LEU A 1 583 ? -39.311 -8.427 -6.250 1.00 16.19 ? 583 LEU A CD1 1 ATOM 4616 C CD2 . LEU A 1 583 ? -37.448 -9.809 -5.337 1.00 18.63 ? 583 LEU A CD2 1 ATOM 4617 N N . CYS A 1 584 ? -39.630 -12.302 -8.775 1.00 21.05 ? 584 CYS A N 1 ATOM 4618 C CA . CYS A 1 584 ? -39.059 -12.381 -10.123 1.00 20.67 ? 584 CYS A CA 1 ATOM 4619 C C . CYS A 1 584 ? -40.164 -12.278 -11.186 1.00 20.15 ? 584 CYS A C 1 ATOM 4620 O O . CYS A 1 584 ? -39.986 -11.631 -12.202 1.00 20.09 ? 584 CYS A O 1 ATOM 4621 C CB . CYS A 1 584 ? -38.233 -13.639 -10.287 1.00 20.62 ? 584 CYS A CB 1 ATOM 4622 S SG . CYS A 1 584 ? -37.093 -13.674 -11.735 1.00 23.52 ? 584 CYS A SG 1 ATOM 4623 N N . ARG A 1 585 ? -41.327 -12.866 -10.923 1.00 19.62 ? 585 ARG A N 1 ATOM 4624 C CA . ARG A 1 585 ? -42.431 -12.795 -11.880 1.00 18.98 ? 585 ARG A CA 1 ATOM 4625 C C . ARG A 1 585 ? -42.895 -11.355 -12.042 1.00 17.88 ? 585 ARG A C 1 ATOM 4626 O O . ARG A 1 585 ? -43.051 -10.880 -13.175 1.00 17.80 ? 585 ARG A O 1 ATOM 4627 C CB . ARG A 1 585 ? -43.592 -13.703 -11.436 1.00 18.88 ? 585 ARG A CB 1 ATOM 4628 C CG . ARG A 1 585 ? -44.902 -13.513 -12.191 1.00 20.68 ? 585 ARG A CG 1 ATOM 4629 C CD . ARG A 1 585 ? -45.806 -14.758 -12.011 1.00 19.76 ? 585 ARG A CD 1 ATOM 4630 N NE . ARG A 1 585 ? -45.823 -15.251 -10.635 1.00 20.86 ? 585 ARG A NE 1 ATOM 4631 C CZ . ARG A 1 585 ? -46.503 -14.675 -9.634 1.00 21.58 ? 585 ARG A CZ 1 ATOM 4632 N NH1 . ARG A 1 585 ? -47.189 -13.569 -9.845 1.00 24.02 ? 585 ARG A NH1 1 ATOM 4633 N NH2 . ARG A 1 585 ? -46.470 -15.173 -8.408 1.00 18.59 ? 585 ARG A NH2 1 ATOM 4634 N N . ARG A 1 586 ? -43.071 -10.641 -10.921 1.00 17.63 ? 586 ARG A N 1 ATOM 4635 C CA . ARG A 1 586 ? -43.454 -9.218 -10.997 1.00 15.98 ? 586 ARG A CA 1 ATOM 4636 C C . ARG A 1 586 ? -42.370 -8.376 -11.652 1.00 15.76 ? 586 ARG A C 1 ATOM 4637 O O . ARG A 1 586 ? -42.656 -7.443 -12.383 1.00 15.66 ? 586 ARG A O 1 ATOM 4638 C CB . ARG A 1 586 ? -43.809 -8.633 -9.628 1.00 15.64 ? 586 ARG A CB 1 ATOM 4639 C CG . ARG A 1 586 ? -45.029 -9.268 -8.983 1.00 16.42 ? 586 ARG A CG 1 ATOM 4640 C CD . ARG A 1 586 ? -46.151 -9.331 -9.974 1.00 17.24 ? 586 ARG A CD 1 ATOM 4641 N NE . ARG A 1 586 ? -47.452 -9.455 -9.328 1.00 19.42 ? 586 ARG A NE 1 ATOM 4642 C CZ . ARG A 1 586 ? -48.607 -9.392 -9.984 1.00 20.75 ? 586 ARG A CZ 1 ATOM 4643 N NH1 . ARG A 1 586 ? -48.603 -9.219 -11.291 1.00 18.64 ? 586 ARG A NH1 1 ATOM 4644 N NH2 . ARG A 1 586 ? -49.766 -9.502 -9.328 1.00 19.97 ? 586 ARG A NH2 1 ATOM 4645 N N . TRP A 1 587 ? -41.107 -8.703 -11.383 1.00 15.63 ? 587 TRP A N 1 ATOM 4646 C CA . TRP A 1 587 ? -40.055 -7.891 -11.899 1.00 15.25 ? 587 TRP A CA 1 ATOM 4647 C C . TRP A 1 587 ? -39.869 -8.133 -13.391 1.00 16.02 ? 587 TRP A C 1 ATOM 4648 O O . TRP A 1 587 ? -39.568 -7.190 -14.141 1.00 16.16 ? 587 TRP A O 1 ATOM 4649 C CB . TRP A 1 587 ? -38.740 -8.238 -11.174 1.00 15.11 ? 587 TRP A CB 1 ATOM 4650 C CG . TRP A 1 587 ? -37.825 -7.058 -11.029 1.00 15.61 ? 587 TRP A CG 1 ATOM 4651 C CD1 . TRP A 1 587 ? -37.677 -6.003 -11.893 1.00 15.42 ? 587 TRP A CD1 1 ATOM 4652 C CD2 . TRP A 1 587 ? -36.875 -6.852 -9.965 1.00 15.96 ? 587 TRP A CD2 1 ATOM 4653 N NE1 . TRP A 1 587 ? -36.698 -5.143 -11.432 1.00 16.40 ? 587 TRP A NE1 1 ATOM 4654 C CE2 . TRP A 1 587 ? -36.195 -5.638 -10.244 1.00 16.79 ? 587 TRP A CE2 1 ATOM 4655 C CE3 . TRP A 1 587 ? -36.553 -7.568 -8.797 1.00 13.81 ? 587 TRP A CE3 1 ATOM 4656 C CZ2 . TRP A 1 587 ? -35.198 -5.115 -9.382 1.00 16.55 ? 587 TRP A CZ2 1 ATOM 4657 C CZ3 . TRP A 1 587 ? -35.545 -7.032 -7.931 1.00 15.01 ? 587 TRP A CZ3 1 ATOM 4658 C CH2 . TRP A 1 587 ? -34.913 -5.822 -8.232 1.00 14.54 ? 587 TRP A CH2 1 ATOM 4659 N N . MET A 1 588 ? -40.061 -9.381 -13.833 1.00 15.51 ? 588 MET A N 1 ATOM 4660 C CA . MET A 1 588 ? -40.052 -9.693 -15.263 1.00 15.70 ? 588 MET A CA 1 ATOM 4661 C C . MET A 1 588 ? -41.148 -8.970 -16.003 1.00 16.41 ? 588 MET A C 1 ATOM 4662 O O . MET A 1 588 ? -40.905 -8.466 -17.102 1.00 15.54 ? 588 MET A O 1 ATOM 4663 C CB . MET A 1 588 ? -40.111 -11.205 -15.554 1.00 15.80 ? 588 MET A CB 1 ATOM 4664 C CG . MET A 1 588 ? -38.733 -11.891 -15.370 1.00 17.29 ? 588 MET A CG 1 ATOM 4665 S SD . MET A 1 588 ? -37.447 -11.363 -16.549 1.00 20.77 ? 588 MET A SD 1 ATOM 4666 C CE . MET A 1 588 ? -38.125 -11.800 -18.151 1.00 21.06 ? 588 MET A CE 1 ATOM 4667 N N . GLN A 1 589 ? -42.344 -8.912 -15.402 1.00 15.60 ? 589 GLN A N 1 ATOM 4668 C CA . GLN A 1 589 ? -43.459 -8.155 -15.985 1.00 16.40 ? 589 GLN A CA 1 ATOM 4669 C C . GLN A 1 589 ? -43.140 -6.692 -16.174 1.00 16.96 ? 589 GLN A C 1 ATOM 4670 O O . GLN A 1 589 ? -43.390 -6.136 -17.243 1.00 17.39 ? 589 GLN A O 1 ATOM 4671 C CB . GLN A 1 589 ? -44.692 -8.274 -15.075 1.00 17.40 ? 589 GLN A CB 1 ATOM 4672 C CG . GLN A 1 589 ? -45.266 -9.685 -15.166 1.00 18.96 ? 589 GLN A CG 1 ATOM 4673 C CD . GLN A 1 589 ? -46.328 -10.016 -14.125 1.00 17.94 ? 589 GLN A CD 1 ATOM 4674 O OE1 . GLN A 1 589 ? -46.577 -9.267 -13.164 1.00 18.50 ? 589 GLN A OE1 1 ATOM 4675 N NE2 . GLN A 1 589 ? -46.931 -11.166 -14.304 1.00 19.81 ? 589 GLN A NE2 1 ATOM 4676 N N . LEU A 1 590 ? -42.551 -6.071 -15.137 1.00 16.89 ? 590 LEU A N 1 ATOM 4677 C CA . LEU A 1 590 ? -42.131 -4.674 -15.216 1.00 16.71 ? 590 LEU A CA 1 ATOM 4678 C C . LEU A 1 590 ? -40.960 -4.534 -16.158 1.00 16.00 ? 590 LEU A C 1 ATOM 4679 O O . LEU A 1 590 ? -40.906 -3.586 -16.954 1.00 15.28 ? 590 LEU A O 1 ATOM 4680 C CB . LEU A 1 590 ? -41.731 -4.124 -13.835 1.00 15.50 ? 590 LEU A CB 1 ATOM 4681 C CG . LEU A 1 590 ? -41.183 -2.696 -13.837 1.00 16.66 ? 590 LEU A CG 1 ATOM 4682 C CD1 . LEU A 1 590 ? -42.152 -1.696 -14.559 1.00 16.59 ? 590 LEU A CD1 1 ATOM 4683 C CD2 . LEU A 1 590 ? -41.012 -2.330 -12.393 1.00 18.92 ? 590 LEU A CD2 1 ATOM 4684 N N . GLY A 1 591 ? -39.992 -5.442 -15.976 1.00 16.68 ? 591 GLY A N 1 ATOM 4685 C CA . GLY A 1 591 ? -38.752 -5.471 -16.737 1.00 17.87 ? 591 GLY A CA 1 ATOM 4686 C C . GLY A 1 591 ? -38.909 -5.564 -18.239 1.00 16.85 ? 591 GLY A C 1 ATOM 4687 O O . GLY A 1 591 ? -38.025 -5.126 -18.980 1.00 16.64 ? 591 GLY A O 1 ATOM 4688 N N . ALA A 1 592 ? -40.030 -6.131 -18.686 1.00 16.70 ? 592 ALA A N 1 ATOM 4689 C CA . ALA A 1 592 ? -40.343 -6.129 -20.100 1.00 15.95 ? 592 ALA A CA 1 ATOM 4690 C C . ALA A 1 592 ? -40.491 -4.714 -20.657 1.00 15.85 ? 592 ALA A C 1 ATOM 4691 O O . ALA A 1 592 ? -40.409 -4.506 -21.863 1.00 15.71 ? 592 ALA A O 1 ATOM 4692 C CB . ALA A 1 592 ? -41.602 -6.992 -20.386 1.00 16.39 ? 592 ALA A CB 1 ATOM 4693 N N . PHE A 1 593 ? -40.729 -3.736 -19.786 1.00 15.57 ? 593 PHE A N 1 ATOM 4694 C CA . PHE A 1 593 ? -40.869 -2.322 -20.211 1.00 15.86 ? 593 PHE A CA 1 ATOM 4695 C C . PHE A 1 593 ? -39.761 -1.365 -19.740 1.00 15.81 ? 593 PHE A C 1 ATOM 4696 O O . PHE A 1 593 ? -39.909 -0.146 -19.856 1.00 16.19 ? 593 PHE A O 1 ATOM 4697 C CB . PHE A 1 593 ? -42.264 -1.866 -19.799 1.00 16.06 ? 593 PHE A CB 1 ATOM 4698 C CG . PHE A 1 593 ? -43.298 -2.747 -20.408 1.00 15.85 ? 593 PHE A CG 1 ATOM 4699 C CD1 . PHE A 1 593 ? -43.691 -2.526 -21.738 1.00 16.75 ? 593 PHE A CD1 1 ATOM 4700 C CD2 . PHE A 1 593 ? -43.719 -3.903 -19.755 1.00 14.25 ? 593 PHE A CD2 1 ATOM 4701 C CE1 . PHE A 1 593 ? -44.595 -3.396 -22.380 1.00 14.73 ? 593 PHE A CE1 1 ATOM 4702 C CE2 . PHE A 1 593 ? -44.664 -4.786 -20.404 1.00 14.47 ? 593 PHE A CE2 1 ATOM 4703 C CZ . PHE A 1 593 ? -45.061 -4.513 -21.697 1.00 13.63 ? 593 PHE A CZ 1 ATOM 4704 N N . TYR A 1 594 ? -38.657 -1.887 -19.194 1.00 14.39 ? 594 TYR A N 1 ATOM 4705 C CA . TYR A 1 594 ? -37.537 -0.988 -18.930 1.00 14.79 ? 594 TYR A CA 1 ATOM 4706 C C . TYR A 1 594 ? -36.920 -0.728 -20.302 1.00 16.48 ? 594 TYR A C 1 ATOM 4707 O O . TYR A 1 594 ? -36.934 -1.634 -21.140 1.00 17.39 ? 594 TYR A O 1 ATOM 4708 C CB . TYR A 1 594 ? -36.455 -1.648 -18.067 1.00 13.79 ? 594 TYR A CB 1 ATOM 4709 C CG . TYR A 1 594 ? -36.764 -1.852 -16.611 1.00 14.64 ? 594 TYR A CG 1 ATOM 4710 C CD1 . TYR A 1 594 ? -37.291 -0.835 -15.806 1.00 16.21 ? 594 TYR A CD1 1 ATOM 4711 C CD2 . TYR A 1 594 ? -36.492 -3.085 -16.018 1.00 15.46 ? 594 TYR A CD2 1 ATOM 4712 C CE1 . TYR A 1 594 ? -37.555 -1.066 -14.423 1.00 14.16 ? 594 TYR A CE1 1 ATOM 4713 C CE2 . TYR A 1 594 ? -36.729 -3.315 -14.681 1.00 15.98 ? 594 TYR A CE2 1 ATOM 4714 C CZ . TYR A 1 594 ? -37.255 -2.312 -13.891 1.00 14.61 ? 594 TYR A CZ 1 ATOM 4715 O OH . TYR A 1 594 ? -37.460 -2.620 -12.571 1.00 16.67 ? 594 TYR A OH 1 ATOM 4716 N N . PRO A 1 595 ? -36.420 0.492 -20.556 1.00 17.89 ? 595 PRO A N 1 ATOM 4717 C CA . PRO A 1 595 ? -35.784 0.747 -21.844 1.00 17.18 ? 595 PRO A CA 1 ATOM 4718 C C . PRO A 1 595 ? -34.557 -0.114 -22.138 1.00 18.31 ? 595 PRO A C 1 ATOM 4719 O O . PRO A 1 595 ? -34.368 -0.499 -23.289 1.00 19.05 ? 595 PRO A O 1 ATOM 4720 C CB . PRO A 1 595 ? -35.453 2.240 -21.825 1.00 17.02 ? 595 PRO A CB 1 ATOM 4721 C CG . PRO A 1 595 ? -36.080 2.803 -20.632 1.00 18.99 ? 595 PRO A CG 1 ATOM 4722 C CD . PRO A 1 595 ? -36.505 1.692 -19.699 1.00 17.82 ? 595 PRO A CD 1 ATOM 4723 N N . PHE A 1 596 ? -33.758 -0.410 -21.112 1.00 17.21 ? 596 PHE A N 1 ATOM 4724 C CA . PHE A 1 596 ? -32.739 -1.468 -21.167 1.00 17.04 ? 596 PHE A CA 1 ATOM 4725 C C . PHE A 1 596 ? -33.269 -2.601 -20.289 1.00 16.80 ? 596 PHE A C 1 ATOM 4726 O O . PHE A 1 596 ? -33.407 -2.422 -19.079 1.00 16.04 ? 596 PHE A O 1 ATOM 4727 C CB . PHE A 1 596 ? -31.410 -0.981 -20.584 1.00 17.14 ? 596 PHE A CB 1 ATOM 4728 C CG . PHE A 1 596 ? -30.378 -2.052 -20.490 1.00 17.74 ? 596 PHE A CG 1 ATOM 4729 C CD1 . PHE A 1 596 ? -29.970 -2.715 -21.652 1.00 18.46 ? 596 PHE A CD1 1 ATOM 4730 C CD2 . PHE A 1 596 ? -29.834 -2.438 -19.259 1.00 17.98 ? 596 PHE A CD2 1 ATOM 4731 C CE1 . PHE A 1 596 ? -29.065 -3.726 -21.596 1.00 15.60 ? 596 PHE A CE1 1 ATOM 4732 C CE2 . PHE A 1 596 ? -28.866 -3.460 -19.193 1.00 15.35 ? 596 PHE A CE2 1 ATOM 4733 C CZ . PHE A 1 596 ? -28.497 -4.107 -20.378 1.00 18.63 ? 596 PHE A CZ 1 ATOM 4734 N N . SER A 1 597 ? -33.587 -3.739 -20.922 1.00 16.71 ? 597 SER A N 1 ATOM 4735 C CA . SER A 1 597 ? -34.266 -4.909 -20.296 1.00 16.87 ? 597 SER A CA 1 ATOM 4736 C C . SER A 1 597 ? -33.278 -6.077 -20.189 1.00 17.05 ? 597 SER A C 1 ATOM 4737 O O . SER A 1 597 ? -33.048 -6.794 -21.183 1.00 18.11 ? 597 SER A O 1 ATOM 4738 C CB . SER A 1 597 ? -35.457 -5.344 -21.168 1.00 15.68 ? 597 SER A CB 1 ATOM 4739 O OG . SER A 1 597 ? -36.140 -6.427 -20.542 1.00 16.42 ? 597 SER A OG 1 ATOM 4740 N N . ARG A 1 598 ? -32.679 -6.252 -19.015 1.00 16.62 ? 598 ARG A N 1 ATOM 4741 C CA . ARG A 1 598 ? -31.738 -7.322 -18.785 1.00 16.08 ? 598 ARG A CA 1 ATOM 4742 C C . ARG A 1 598 ? -31.944 -8.012 -17.450 1.00 14.95 ? 598 ARG A C 1 ATOM 4743 O O . ARG A 1 598 ? -32.048 -7.361 -16.407 1.00 15.56 ? 598 ARG A O 1 ATOM 4744 C CB . ARG A 1 598 ? -30.281 -6.830 -18.889 1.00 15.08 ? 598 ARG A CB 1 ATOM 4745 C CG . ARG A 1 598 ? -29.311 -7.909 -18.561 1.00 17.41 ? 598 ARG A CG 1 ATOM 4746 C CD . ARG A 1 598 ? -27.891 -7.435 -18.728 1.00 13.34 ? 598 ARG A CD 1 ATOM 4747 N NE . ARG A 1 598 ? -27.471 -6.631 -17.579 1.00 18.73 ? 598 ARG A NE 1 ATOM 4748 C CZ . ARG A 1 598 ? -26.209 -6.497 -17.197 1.00 19.31 ? 598 ARG A CZ 1 ATOM 4749 N NH1 . ARG A 1 598 ? -25.249 -7.026 -17.927 1.00 18.58 ? 598 ARG A NH1 1 ATOM 4750 N NH2 . ARG A 1 598 ? -25.904 -5.783 -16.120 1.00 22.87 ? 598 ARG A NH2 1 ATOM 4751 N N . ASN A 1 599 ? -32.037 -9.333 -17.492 1.00 14.96 ? 599 ASN A N 1 ATOM 4752 C CA . ASN A 1 599 ? -32.084 -10.166 -16.290 1.00 16.60 ? 599 ASN A CA 1 ATOM 4753 C C . ASN A 1 599 ? -30.628 -10.583 -16.049 1.00 17.35 ? 599 ASN A C 1 ATOM 4754 O O . ASN A 1 599 ? -30.013 -11.259 -16.893 1.00 19.25 ? 599 ASN A O 1 ATOM 4755 C CB . ASN A 1 599 ? -32.987 -11.389 -16.579 1.00 15.99 ? 599 ASN A CB 1 ATOM 4756 C CG . ASN A 1 599 ? -33.091 -12.387 -15.406 1.00 17.62 ? 599 ASN A CG 1 ATOM 4757 O OD1 . ASN A 1 599 ? -32.098 -12.752 -14.754 1.00 16.32 ? 599 ASN A OD1 1 ATOM 4758 N ND2 . ASN A 1 599 ? -34.318 -12.855 -15.155 1.00 16.87 ? 599 ASN A ND2 1 ATOM 4759 N N . HIS A 1 600 ? -30.068 -10.154 -14.923 1.00 17.03 ? 600 HIS A N 1 ATOM 4760 C CA . HIS A 1 600 ? -28.700 -10.488 -14.559 1.00 17.77 ? 600 HIS A CA 1 ATOM 4761 C C . HIS A 1 600 ? -28.657 -10.922 -13.069 1.00 18.17 ? 600 HIS A C 1 ATOM 4762 O O . HIS A 1 600 ? -29.485 -10.484 -12.272 1.00 20.00 ? 600 HIS A O 1 ATOM 4763 C CB . HIS A 1 600 ? -27.853 -9.273 -14.860 1.00 17.81 ? 600 HIS A CB 1 ATOM 4764 C CG . HIS A 1 600 ? -26.426 -9.375 -14.429 1.00 16.20 ? 600 HIS A CG 1 ATOM 4765 N ND1 . HIS A 1 600 ? -25.588 -10.396 -14.818 1.00 20.08 ? 600 HIS A ND1 1 ATOM 4766 C CD2 . HIS A 1 600 ? -25.665 -8.521 -13.710 1.00 18.09 ? 600 HIS A CD2 1 ATOM 4767 C CE1 . HIS A 1 600 ? -24.377 -10.194 -14.322 1.00 18.48 ? 600 HIS A CE1 1 ATOM 4768 N NE2 . HIS A 1 600 ? -24.397 -9.057 -13.647 1.00 17.99 ? 600 HIS A NE2 1 ATOM 4769 N N . ASN A 1 601 ? -27.700 -11.781 -12.681 1.00 17.65 ? 601 ASN A N 1 ATOM 4770 C CA . ASN A 1 601 ? -27.732 -12.440 -11.384 1.00 16.58 ? 601 ASN A CA 1 ATOM 4771 C C . ASN A 1 601 ? -26.278 -12.547 -10.869 1.00 17.54 ? 601 ASN A C 1 ATOM 4772 O O . ASN A 1 601 ? -25.360 -12.633 -11.667 1.00 17.17 ? 601 ASN A O 1 ATOM 4773 C CB . ASN A 1 601 ? -28.312 -13.826 -11.577 1.00 16.33 ? 601 ASN A CB 1 ATOM 4774 C CG . ASN A 1 601 ? -28.573 -14.581 -10.264 1.00 17.10 ? 601 ASN A CG 1 ATOM 4775 O OD1 . ASN A 1 601 ? -28.654 -14.005 -9.168 1.00 17.17 ? 601 ASN A OD1 1 ATOM 4776 N ND2 . ASN A 1 601 ? -28.734 -15.895 -10.392 1.00 19.39 ? 601 ASN A ND2 1 ATOM 4777 N N . GLY A 1 602 ? -26.093 -12.503 -9.551 1.00 18.33 ? 602 GLY A N 1 ATOM 4778 C CA . GLY A 1 602 ? -24.745 -12.568 -8.954 1.00 18.42 ? 602 GLY A CA 1 ATOM 4779 C C . GLY A 1 602 ? -24.221 -14.005 -8.868 1.00 19.91 ? 602 GLY A C 1 ATOM 4780 O O . GLY A 1 602 ? -24.870 -14.957 -9.317 1.00 19.56 ? 602 GLY A O 1 ATOM 4781 N N . GLN A 1 603 ? -23.032 -14.144 -8.300 1.00 21.10 ? 603 GLN A N 1 ATOM 4782 C CA . GLN A 1 603 ? -22.339 -15.417 -8.263 1.00 23.24 ? 603 GLN A CA 1 ATOM 4783 C C . GLN A 1 603 ? -23.002 -16.321 -7.238 1.00 23.91 ? 603 GLN A C 1 ATOM 4784 O O . GLN A 1 603 ? -23.338 -15.864 -6.154 1.00 24.25 ? 603 GLN A O 1 ATOM 4785 C CB . GLN A 1 603 ? -20.880 -15.178 -7.886 1.00 24.10 ? 603 GLN A CB 1 ATOM 4786 C CG . GLN A 1 603 ? -20.103 -16.451 -7.612 1.00 28.64 ? 603 GLN A CG 1 ATOM 4787 C CD . GLN A 1 603 ? -18.625 -16.186 -7.377 1.00 33.68 ? 603 GLN A CD 1 ATOM 4788 O OE1 . GLN A 1 603 ? -18.229 -15.180 -6.775 1.00 36.02 ? 603 GLN A OE1 1 ATOM 4789 N NE2 . GLN A 1 603 ? -17.798 -17.103 -7.847 1.00 36.77 ? 603 GLN A NE2 1 ATOM 4790 N N . GLY A 1 604 ? -23.230 -17.584 -7.611 1.00 24.49 ? 604 GLY A N 1 ATOM 4791 C CA . GLY A 1 604 ? -23.656 -18.623 -6.656 1.00 24.94 ? 604 GLY A CA 1 ATOM 4792 C C . GLY A 1 604 ? -25.132 -18.704 -6.361 1.00 25.66 ? 604 GLY A C 1 ATOM 4793 O O . GLY A 1 604 ? -25.587 -19.756 -5.926 1.00 25.76 ? 604 GLY A O 1 ATOM 4794 N N . TYR A 1 605 ? -25.892 -17.632 -6.615 1.00 24.91 ? 605 TYR A N 1 ATOM 4795 C CA . TYR A 1 605 ? -27.321 -17.614 -6.311 1.00 25.33 ? 605 TYR A CA 1 ATOM 4796 C C . TYR A 1 605 ? -28.101 -18.528 -7.253 1.00 25.75 ? 605 TYR A C 1 ATOM 4797 O O . TYR A 1 605 ? -27.642 -18.847 -8.345 1.00 26.14 ? 605 TYR A O 1 ATOM 4798 C CB . TYR A 1 605 ? -27.899 -16.182 -6.299 1.00 25.37 ? 605 TYR A CB 1 ATOM 4799 C CG . TYR A 1 605 ? -27.082 -15.254 -5.431 1.00 25.36 ? 605 TYR A CG 1 ATOM 4800 C CD1 . TYR A 1 605 ? -27.054 -15.407 -4.040 1.00 25.16 ? 605 TYR A CD1 1 ATOM 4801 C CD2 . TYR A 1 605 ? -26.297 -14.259 -5.999 1.00 23.71 ? 605 TYR A CD2 1 ATOM 4802 C CE1 . TYR A 1 605 ? -26.277 -14.570 -3.244 1.00 26.76 ? 605 TYR A CE1 1 ATOM 4803 C CE2 . TYR A 1 605 ? -25.511 -13.433 -5.219 1.00 25.37 ? 605 TYR A CE2 1 ATOM 4804 C CZ . TYR A 1 605 ? -25.506 -13.599 -3.843 1.00 26.02 ? 605 TYR A CZ 1 ATOM 4805 O OH . TYR A 1 605 ? -24.741 -12.759 -3.080 1.00 28.33 ? 605 TYR A OH 1 ATOM 4806 N N . LYS A 1 606 ? -29.274 -18.956 -6.813 1.00 25.71 ? 606 LYS A N 1 ATOM 4807 C CA . LYS A 1 606 ? -30.080 -19.871 -7.601 1.00 27.56 ? 606 LYS A CA 1 ATOM 4808 C C . LYS A 1 606 ? -30.359 -19.203 -8.951 1.00 26.56 ? 606 LYS A C 1 ATOM 4809 O O . LYS A 1 606 ? -30.433 -17.977 -9.032 1.00 25.86 ? 606 LYS A O 1 ATOM 4810 C CB . LYS A 1 606 ? -31.344 -20.254 -6.827 1.00 27.78 ? 606 LYS A CB 1 ATOM 4811 C CG . LYS A 1 606 ? -32.623 -19.687 -7.335 1.00 30.71 ? 606 LYS A CG 1 ATOM 4812 C CD . LYS A 1 606 ? -33.826 -20.305 -6.583 1.00 31.73 ? 606 LYS A CD 1 ATOM 4813 C CE . LYS A 1 606 ? -35.151 -19.824 -7.208 1.00 39.22 ? 606 LYS A CE 1 ATOM 4814 N NZ . LYS A 1 606 ? -36.268 -19.673 -6.207 1.00 43.44 ? 606 LYS A NZ 1 ATOM 4815 N N . ASP A 1 607 ? -30.440 -19.995 -10.015 1.00 25.66 ? 607 ASP A N 1 ATOM 4816 C CA . ASP A 1 607 ? -30.724 -19.469 -11.345 1.00 25.21 ? 607 ASP A CA 1 ATOM 4817 C C . ASP A 1 607 ? -32.015 -18.647 -11.325 1.00 23.69 ? 607 ASP A C 1 ATOM 4818 O O . ASP A 1 607 ? -32.982 -18.982 -10.636 1.00 23.91 ? 607 ASP A O 1 ATOM 4819 C CB . ASP A 1 607 ? -30.878 -20.601 -12.366 1.00 24.92 ? 607 ASP A CB 1 ATOM 4820 C CG . ASP A 1 607 ? -29.640 -21.419 -12.517 1.00 26.89 ? 607 ASP A CG 1 ATOM 4821 O OD1 . ASP A 1 607 ? -28.550 -20.927 -12.137 1.00 30.84 ? 607 ASP A OD1 1 ATOM 4822 O OD2 . ASP A 1 607 ? -29.744 -22.561 -13.039 1.00 27.42 ? 607 ASP A OD2 1 ATOM 4823 N N . GLN A 1 608 ? -32.028 -17.577 -12.111 1.00 22.91 ? 608 GLN A N 1 ATOM 4824 C CA . GLN A 1 608 ? -33.225 -16.754 -12.219 1.00 21.70 ? 608 GLN A CA 1 ATOM 4825 C C . GLN A 1 608 ? -33.535 -16.367 -13.658 1.00 21.31 ? 608 GLN A C 1 ATOM 4826 O O . GLN A 1 608 ? -34.371 -15.509 -13.891 1.00 19.77 ? 608 GLN A O 1 ATOM 4827 C CB . GLN A 1 608 ? -33.110 -15.523 -11.300 1.00 21.50 ? 608 GLN A CB 1 ATOM 4828 C CG . GLN A 1 608 ? -32.040 -14.551 -11.674 1.00 21.54 ? 608 GLN A CG 1 ATOM 4829 C CD . GLN A 1 608 ? -31.831 -13.444 -10.621 1.00 21.84 ? 608 GLN A CD 1 ATOM 4830 O OE1 . GLN A 1 608 ? -31.846 -13.703 -9.415 1.00 22.72 ? 608 GLN A OE1 1 ATOM 4831 N NE2 . GLN A 1 608 ? -31.637 -12.209 -11.086 1.00 19.17 ? 608 GLN A NE2 1 ATOM 4832 N N . ASP A 1 609 ? -32.857 -17.003 -14.625 1.00 20.15 ? 609 ASP A N 1 ATOM 4833 C CA . ASP A 1 609 ? -33.255 -16.867 -15.993 1.00 19.84 ? 609 ASP A CA 1 ATOM 4834 C C . ASP A 1 609 ? -34.705 -17.353 -16.112 1.00 19.45 ? 609 ASP A C 1 ATOM 4835 O O . ASP A 1 609 ? -35.140 -18.232 -15.368 1.00 20.17 ? 609 ASP A O 1 ATOM 4836 C CB . ASP A 1 609 ? -32.340 -17.645 -16.937 1.00 20.81 ? 609 ASP A CB 1 ATOM 4837 C CG . ASP A 1 609 ? -32.299 -19.117 -16.620 1.00 21.55 ? 609 ASP A CG 1 ATOM 4838 O OD1 . ASP A 1 609 ? -31.552 -19.497 -15.700 1.00 21.78 ? 609 ASP A OD1 1 ATOM 4839 O OD2 . ASP A 1 609 ? -32.983 -19.893 -17.321 1.00 22.07 ? 609 ASP A OD2 1 ATOM 4840 N N . PRO A 1 610 ? -35.483 -16.730 -16.990 1.00 18.74 ? 610 PRO A N 1 ATOM 4841 C CA . PRO A 1 610 ? -36.918 -17.064 -17.005 1.00 19.46 ? 610 PRO A CA 1 ATOM 4842 C C . PRO A 1 610 ? -37.270 -18.574 -17.111 1.00 20.28 ? 610 PRO A C 1 ATOM 4843 O O . PRO A 1 610 ? -38.110 -19.053 -16.344 1.00 20.11 ? 610 PRO A O 1 ATOM 4844 C CB . PRO A 1 610 ? -37.436 -16.250 -18.196 1.00 18.64 ? 610 PRO A CB 1 ATOM 4845 C CG . PRO A 1 610 ? -36.532 -15.036 -18.218 1.00 19.73 ? 610 PRO A CG 1 ATOM 4846 C CD . PRO A 1 610 ? -35.165 -15.656 -17.956 1.00 18.89 ? 610 PRO A CD 1 ATOM 4847 N N . ALA A 1 611 ? -36.609 -19.313 -18.006 1.00 20.99 ? 611 ALA A N 1 ATOM 4848 C CA . ALA A 1 611 ? -36.965 -20.725 -18.241 1.00 21.43 ? 611 ALA A CA 1 ATOM 4849 C C . ALA A 1 611 ? -36.569 -21.654 -17.085 1.00 22.49 ? 611 ALA A C 1 ATOM 4850 O O . ALA A 1 611 ? -37.115 -22.766 -16.965 1.00 22.51 ? 611 ALA A O 1 ATOM 4851 C CB . ALA A 1 611 ? -36.400 -21.215 -19.561 1.00 20.23 ? 611 ALA A CB 1 ATOM 4852 N N . SER A 1 612 ? -35.685 -21.175 -16.191 1.00 23.39 ? 612 SER A N 1 ATOM 4853 C CA . SER A 1 612 ? -35.300 -21.928 -14.977 1.00 24.09 ? 612 SER A CA 1 ATOM 4854 C C . SER A 1 612 ? -36.467 -22.177 -14.011 1.00 25.36 ? 612 SER A C 1 ATOM 4855 O O . SER A 1 612 ? -36.433 -23.106 -13.199 1.00 25.36 ? 612 SER A O 1 ATOM 4856 C CB . SER A 1 612 ? -34.129 -21.257 -14.249 1.00 24.27 ? 612 SER A CB 1 ATOM 4857 O OG . SER A 1 612 ? -34.583 -20.129 -13.505 1.00 25.83 ? 612 SER A OG 1 ATOM 4858 N N . PHE A 1 613 ? -37.524 -21.376 -14.128 1.00 25.43 ? 613 PHE A N 1 ATOM 4859 C CA . PHE A 1 613 ? -38.705 -21.559 -13.272 1.00 25.86 ? 613 PHE A CA 1 ATOM 4860 C C . PHE A 1 613 ? -39.636 -22.667 -13.705 1.00 26.94 ? 613 PHE A C 1 ATOM 4861 O O . PHE A 1 613 ? -40.680 -22.932 -13.055 1.00 27.67 ? 613 PHE A O 1 ATOM 4862 C CB . PHE A 1 613 ? -39.432 -20.222 -13.110 1.00 25.24 ? 613 PHE A CB 1 ATOM 4863 C CG . PHE A 1 613 ? -38.600 -19.216 -12.379 1.00 23.65 ? 613 PHE A CG 1 ATOM 4864 C CD1 . PHE A 1 613 ? -38.778 -19.014 -11.022 1.00 24.38 ? 613 PHE A CD1 1 ATOM 4865 C CD2 . PHE A 1 613 ? -37.589 -18.514 -13.046 1.00 22.86 ? 613 PHE A CD2 1 ATOM 4866 C CE1 . PHE A 1 613 ? -37.955 -18.080 -10.327 1.00 25.87 ? 613 PHE A CE1 1 ATOM 4867 C CE2 . PHE A 1 613 ? -36.786 -17.569 -12.373 1.00 21.89 ? 613 PHE A CE2 1 ATOM 4868 C CZ . PHE A 1 613 ? -36.970 -17.368 -11.019 1.00 23.15 ? 613 PHE A CZ 1 ATOM 4869 N N . GLY A 1 614 ? -39.278 -23.312 -14.809 1.00 27.85 ? 614 GLY A N 1 ATOM 4870 C CA . GLY A 1 614 ? -40.090 -24.390 -15.341 1.00 28.43 ? 614 GLY A CA 1 ATOM 4871 C C . GLY A 1 614 ? -40.720 -24.077 -16.677 1.00 29.57 ? 614 GLY A C 1 ATOM 4872 O O . GLY A 1 614 ? -41.240 -22.969 -16.904 1.00 28.45 ? 614 GLY A O 1 ATOM 4873 N N . ALA A 1 615 ? -40.679 -25.068 -17.566 1.00 30.26 ? 615 ALA A N 1 ATOM 4874 C CA . ALA A 1 615 ? -41.171 -24.915 -18.931 1.00 31.63 ? 615 ALA A CA 1 ATOM 4875 C C . ALA A 1 615 ? -42.614 -24.493 -18.991 1.00 32.28 ? 615 ALA A C 1 ATOM 4876 O O . ALA A 1 615 ? -43.017 -23.869 -19.973 1.00 33.61 ? 615 ALA A O 1 ATOM 4877 C CB . ALA A 1 615 ? -40.990 -26.205 -19.715 1.00 32.57 ? 615 ALA A CB 1 ATOM 4878 N N . ASP A 1 616 ? -43.398 -24.845 -17.975 1.00 32.31 ? 616 ASP A N 1 ATOM 4879 C CA . ASP A 1 616 ? -44.827 -24.539 -17.985 1.00 32.77 ? 616 ASP A CA 1 ATOM 4880 C C . ASP A 1 616 ? -45.243 -23.638 -16.816 1.00 30.65 ? 616 ASP A C 1 ATOM 4881 O O . ASP A 1 616 ? -46.421 -23.558 -16.468 1.00 30.92 ? 616 ASP A O 1 ATOM 4882 C CB . ASP A 1 616 ? -45.676 -25.836 -18.043 1.00 34.42 ? 616 ASP A CB 1 ATOM 4883 C CG . ASP A 1 616 ? -45.668 -26.501 -19.449 1.00 40.20 ? 616 ASP A CG 1 ATOM 4884 O OD1 . ASP A 1 616 ? -45.390 -27.732 -19.549 1.00 45.29 ? 616 ASP A OD1 1 ATOM 4885 O OD2 . ASP A 1 616 ? -45.933 -25.796 -20.467 1.00 45.10 ? 616 ASP A OD2 1 ATOM 4886 N N . SER A 1 617 ? -44.273 -22.938 -16.232 1.00 28.44 ? 617 SER A N 1 ATOM 4887 C CA . SER A 1 617 ? -44.514 -22.095 -15.053 1.00 26.07 ? 617 SER A CA 1 ATOM 4888 C C . SER A 1 617 ? -45.254 -20.827 -15.396 1.00 24.40 ? 617 SER A C 1 ATOM 4889 O O . SER A 1 617 ? -45.165 -20.342 -16.513 1.00 23.75 ? 617 SER A O 1 ATOM 4890 C CB . SER A 1 617 ? -43.198 -21.715 -14.404 1.00 25.36 ? 617 SER A CB 1 ATOM 4891 O OG . SER A 1 617 ? -42.362 -20.984 -15.295 1.00 24.75 ? 617 SER A OG 1 ATOM 4892 N N . LEU A 1 618 ? -45.979 -20.289 -14.419 1.00 23.95 ? 618 LEU A N 1 ATOM 4893 C CA . LEU A 1 618 ? -46.581 -18.973 -14.545 1.00 23.43 ? 618 LEU A CA 1 ATOM 4894 C C . LEU A 1 618 ? -45.545 -17.869 -14.859 1.00 22.83 ? 618 LEU A C 1 ATOM 4895 O O . LEU A 1 618 ? -45.813 -16.984 -15.660 1.00 21.69 ? 618 LEU A O 1 ATOM 4896 C CB . LEU A 1 618 ? -47.403 -18.628 -13.294 1.00 23.75 ? 618 LEU A CB 1 ATOM 4897 C CG . LEU A 1 618 ? -48.100 -17.269 -13.371 1.00 24.28 ? 618 LEU A CG 1 ATOM 4898 C CD1 . LEU A 1 618 ? -49.071 -17.207 -14.551 1.00 28.75 ? 618 LEU A CD1 1 ATOM 4899 C CD2 . LEU A 1 618 ? -48.803 -16.953 -12.067 1.00 27.74 ? 618 LEU A CD2 1 ATOM 4900 N N . LEU A 1 619 ? -44.361 -17.943 -14.258 1.00 22.17 ? 619 LEU A N 1 ATOM 4901 C CA . LEU A 1 619 ? -43.331 -16.934 -14.490 1.00 21.51 ? 619 LEU A CA 1 ATOM 4902 C C . LEU A 1 619 ? -42.888 -16.962 -15.939 1.00 21.49 ? 619 LEU A C 1 ATOM 4903 O O . LEU A 1 619 ? -42.809 -15.921 -16.589 1.00 21.81 ? 619 LEU A O 1 ATOM 4904 C CB . LEU A 1 619 ? -42.122 -17.133 -13.551 1.00 21.38 ? 619 LEU A CB 1 ATOM 4905 C CG . LEU A 1 619 ? -41.015 -16.085 -13.667 1.00 20.84 ? 619 LEU A CG 1 ATOM 4906 C CD1 . LEU A 1 619 ? -40.247 -15.933 -12.348 1.00 19.28 ? 619 LEU A CD1 1 ATOM 4907 C CD2 . LEU A 1 619 ? -40.034 -16.322 -14.859 1.00 20.96 ? 619 LEU A CD2 1 ATOM 4908 N N . LEU A 1 620 ? -42.602 -18.154 -16.466 1.00 21.62 ? 620 LEU A N 1 ATOM 4909 C CA . LEU A 1 620 ? -42.144 -18.253 -17.837 1.00 21.43 ? 620 LEU A CA 1 ATOM 4910 C C . LEU A 1 620 ? -43.246 -17.794 -18.783 1.00 20.08 ? 620 LEU A C 1 ATOM 4911 O O . LEU A 1 620 ? -42.999 -17.011 -19.701 1.00 18.00 ? 620 LEU A O 1 ATOM 4912 C CB . LEU A 1 620 ? -41.697 -19.686 -18.184 1.00 22.27 ? 620 LEU A CB 1 ATOM 4913 C CG . LEU A 1 620 ? -41.175 -19.824 -19.615 1.00 23.62 ? 620 LEU A CG 1 ATOM 4914 C CD1 . LEU A 1 620 ? -39.987 -18.883 -19.863 1.00 24.22 ? 620 LEU A CD1 1 ATOM 4915 C CD2 . LEU A 1 620 ? -40.773 -21.285 -19.915 1.00 24.00 ? 620 LEU A CD2 1 ATOM 4916 N N . ASN A 1 621 ? -44.464 -18.270 -18.560 1.00 20.59 ? 621 ASN A N 1 ATOM 4917 C CA . ASN A 1 621 ? -45.570 -17.888 -19.441 1.00 21.57 ? 621 ASN A CA 1 ATOM 4918 C C . ASN A 1 621 ? -45.767 -16.389 -19.471 1.00 21.01 ? 621 ASN A C 1 ATOM 4919 O O . ASN A 1 621 ? -45.911 -15.792 -20.553 1.00 21.80 ? 621 ASN A O 1 ATOM 4920 C CB . ASN A 1 621 ? -46.892 -18.567 -19.032 1.00 22.66 ? 621 ASN A CB 1 ATOM 4921 C CG . ASN A 1 621 ? -46.869 -20.072 -19.269 1.00 28.47 ? 621 ASN A CG 1 ATOM 4922 O OD1 . ASN A 1 621 ? -46.122 -20.579 -20.118 1.00 34.24 ? 621 ASN A OD1 1 ATOM 4923 N ND2 . ASN A 1 621 ? -47.716 -20.802 -18.525 1.00 36.95 ? 621 ASN A ND2 1 ATOM 4924 N N . SER A 1 622 ? -45.775 -15.776 -18.295 1.00 21.06 ? 622 SER A N 1 ATOM 4925 C CA . SER A 1 622 ? -46.010 -14.339 -18.227 1.00 21.09 ? 622 SER A CA 1 ATOM 4926 C C . SER A 1 622 ? -44.850 -13.517 -18.792 1.00 19.86 ? 622 SER A C 1 ATOM 4927 O O . SER A 1 622 ? -45.060 -12.520 -19.516 1.00 18.18 ? 622 SER A O 1 ATOM 4928 C CB . SER A 1 622 ? -46.332 -13.928 -16.810 1.00 22.13 ? 622 SER A CB 1 ATOM 4929 O OG . SER A 1 622 ? -46.614 -12.548 -16.826 1.00 27.85 ? 622 SER A OG 1 ATOM 4930 N N . SER A 1 623 ? -43.626 -13.931 -18.461 1.00 18.32 ? 623 SER A N 1 ATOM 4931 C CA . SER A 1 623 ? -42.456 -13.342 -19.068 1.00 19.25 ? 623 SER A CA 1 ATOM 4932 C C . SER A 1 623 ? -42.508 -13.328 -20.572 1.00 18.53 ? 623 SER A C 1 ATOM 4933 O O . SER A 1 623 ? -42.254 -12.297 -21.198 1.00 19.30 ? 623 SER A O 1 ATOM 4934 C CB . SER A 1 623 ? -41.191 -14.084 -18.614 1.00 19.59 ? 623 SER A CB 1 ATOM 4935 O OG . SER A 1 623 ? -41.067 -13.988 -17.223 1.00 21.02 ? 623 SER A OG 1 ATOM 4936 N N . ARG A 1 624 ? -42.787 -14.488 -21.177 1.00 18.90 ? 624 ARG A N 1 ATOM 4937 C CA . ARG A 1 624 ? -42.817 -14.583 -22.620 1.00 18.91 ? 624 ARG A CA 1 ATOM 4938 C C . ARG A 1 624 ? -43.932 -13.681 -23.136 1.00 18.29 ? 624 ARG A C 1 ATOM 4939 O O . ARG A 1 624 ? -43.766 -13.002 -24.123 1.00 17.26 ? 624 ARG A O 1 ATOM 4940 C CB . ARG A 1 624 ? -43.068 -16.043 -23.079 1.00 18.74 ? 624 ARG A CB 1 ATOM 4941 C CG . ARG A 1 624 ? -43.134 -16.233 -24.594 1.00 19.27 ? 624 ARG A CG 1 ATOM 4942 C CD . ARG A 1 624 ? -43.191 -17.748 -24.944 1.00 22.07 ? 624 ARG A CD 1 ATOM 4943 N NE . ARG A 1 624 ? -44.183 -18.353 -24.071 1.00 26.88 ? 624 ARG A NE 1 ATOM 4944 C CZ . ARG A 1 624 ? -44.035 -19.437 -23.324 1.00 27.55 ? 624 ARG A CZ 1 ATOM 4945 N NH1 . ARG A 1 624 ? -42.927 -20.189 -23.336 1.00 27.74 ? 624 ARG A NH1 1 ATOM 4946 N NH2 . ARG A 1 624 ? -45.061 -19.789 -22.566 1.00 29.59 ? 624 ARG A NH2 1 ATOM 4947 N N . HIS A 1 625 ? -45.050 -13.666 -22.426 1.00 18.46 ? 625 HIS A N 1 ATOM 4948 C CA . HIS A 1 625 ? -46.210 -12.897 -22.863 1.00 18.22 ? 625 HIS A CA 1 ATOM 4949 C C . HIS A 1 625 ? -45.889 -11.401 -22.961 1.00 17.60 ? 625 HIS A C 1 ATOM 4950 O O . HIS A 1 625 ? -46.159 -10.753 -23.995 1.00 16.29 ? 625 HIS A O 1 ATOM 4951 C CB . HIS A 1 625 ? -47.359 -13.101 -21.885 1.00 18.85 ? 625 HIS A CB 1 ATOM 4952 C CG . HIS A 1 625 ? -48.616 -12.408 -22.307 1.00 19.93 ? 625 HIS A CG 1 ATOM 4953 N ND1 . HIS A 1 625 ? -49.111 -11.310 -21.643 1.00 22.54 ? 625 HIS A ND1 1 ATOM 4954 C CD2 . HIS A 1 625 ? -49.448 -12.621 -23.355 1.00 23.15 ? 625 HIS A CD2 1 ATOM 4955 C CE1 . HIS A 1 625 ? -50.218 -10.893 -22.239 1.00 23.32 ? 625 HIS A CE1 1 ATOM 4956 N NE2 . HIS A 1 625 ? -50.434 -11.659 -23.293 1.00 25.54 ? 625 HIS A NE2 1 ATOM 4957 N N . TYR A 1 626 ? -45.323 -10.856 -21.884 1.00 17.18 ? 626 TYR A N 1 ATOM 4958 C CA . TYR A 1 626 ? -45.051 -9.422 -21.823 1.00 16.74 ? 626 TYR A CA 1 ATOM 4959 C C . TYR A 1 626 ? -43.821 -9.058 -22.623 1.00 15.24 ? 626 TYR A C 1 ATOM 4960 O O . TYR A 1 626 ? -43.769 -7.965 -23.195 1.00 15.21 ? 626 TYR A O 1 ATOM 4961 C CB . TYR A 1 626 ? -44.992 -8.903 -20.363 1.00 16.30 ? 626 TYR A CB 1 ATOM 4962 C CG . TYR A 1 626 ? -46.389 -8.772 -19.824 1.00 18.76 ? 626 TYR A CG 1 ATOM 4963 C CD1 . TYR A 1 626 ? -46.867 -9.628 -18.820 1.00 16.95 ? 626 TYR A CD1 1 ATOM 4964 C CD2 . TYR A 1 626 ? -47.255 -7.852 -20.379 1.00 16.37 ? 626 TYR A CD2 1 ATOM 4965 C CE1 . TYR A 1 626 ? -48.207 -9.544 -18.378 1.00 16.58 ? 626 TYR A CE1 1 ATOM 4966 C CE2 . TYR A 1 626 ? -48.605 -7.757 -19.943 1.00 18.36 ? 626 TYR A CE2 1 ATOM 4967 C CZ . TYR A 1 626 ? -49.039 -8.609 -18.930 1.00 15.73 ? 626 TYR A CZ 1 ATOM 4968 O OH . TYR A 1 626 ? -50.341 -8.521 -18.477 1.00 21.09 ? 626 TYR A OH 1 ATOM 4969 N N . LEU A 1 627 ? -42.850 -9.968 -22.715 1.00 15.31 ? 627 LEU A N 1 ATOM 4970 C CA . LEU A 1 627 ? -41.768 -9.727 -23.672 1.00 15.38 ? 627 LEU A CA 1 ATOM 4971 C C . LEU A 1 627 ? -42.290 -9.720 -25.106 1.00 16.19 ? 627 LEU A C 1 ATOM 4972 O O . LEU A 1 627 ? -41.793 -8.957 -25.938 1.00 16.60 ? 627 LEU A O 1 ATOM 4973 C CB . LEU A 1 627 ? -40.593 -10.706 -23.501 1.00 13.05 ? 627 LEU A CB 1 ATOM 4974 C CG . LEU A 1 627 ? -39.750 -10.400 -22.256 1.00 14.73 ? 627 LEU A CG 1 ATOM 4975 C CD1 . LEU A 1 627 ? -38.797 -11.564 -22.024 1.00 15.85 ? 627 LEU A CD1 1 ATOM 4976 C CD2 . LEU A 1 627 ? -39.036 -9.048 -22.446 1.00 14.76 ? 627 LEU A CD2 1 ATOM 4977 N N . ASN A 1 628 ? -43.299 -10.539 -25.411 1.00 16.29 ? 628 ASN A N 1 ATOM 4978 C CA . ASN A 1 628 ? -43.822 -10.510 -26.748 1.00 16.64 ? 628 ASN A CA 1 ATOM 4979 C C . ASN A 1 628 ? -44.548 -9.185 -27.021 1.00 15.04 ? 628 ASN A C 1 ATOM 4980 O O . ASN A 1 628 ? -44.548 -8.699 -28.144 1.00 14.54 ? 628 ASN A O 1 ATOM 4981 C CB . ASN A 1 628 ? -44.725 -11.691 -27.040 1.00 17.43 ? 628 ASN A CB 1 ATOM 4982 C CG . ASN A 1 628 ? -43.964 -12.889 -27.557 1.00 20.26 ? 628 ASN A CG 1 ATOM 4983 O OD1 . ASN A 1 628 ? -44.278 -14.040 -27.207 1.00 24.56 ? 628 ASN A OD1 1 ATOM 4984 N ND2 . ASN A 1 628 ? -42.951 -12.633 -28.356 1.00 19.21 ? 628 ASN A ND2 1 ATOM 4985 N N . ILE A 1 629 ? -45.157 -8.608 -25.982 1.00 14.90 ? 629 ILE A N 1 ATOM 4986 C CA . ILE A 1 629 ? -45.731 -7.269 -26.116 1.00 13.81 ? 629 ILE A CA 1 ATOM 4987 C C . ILE A 1 629 ? -44.632 -6.225 -26.306 1.00 13.65 ? 629 ILE A C 1 ATOM 4988 O O . ILE A 1 629 ? -44.725 -5.351 -27.152 1.00 12.92 ? 629 ILE A O 1 ATOM 4989 C CB . ILE A 1 629 ? -46.634 -6.921 -24.908 1.00 14.20 ? 629 ILE A CB 1 ATOM 4990 C CG1 . ILE A 1 629 ? -47.911 -7.790 -24.989 1.00 12.85 ? 629 ILE A CG1 1 ATOM 4991 C CG2 . ILE A 1 629 ? -46.925 -5.398 -24.921 1.00 14.54 ? 629 ILE A CG2 1 ATOM 4992 C CD1 . ILE A 1 629 ? -48.761 -7.783 -23.695 1.00 15.86 ? 629 ILE A CD1 1 ATOM 4993 N N . ARG A 1 630 ? -43.595 -6.292 -25.491 1.00 12.99 ? 630 ARG A N 1 ATOM 4994 C CA . ARG A 1 630 ? -42.441 -5.374 -25.744 1.00 12.87 ? 630 ARG A CA 1 ATOM 4995 C C . ARG A 1 630 ? -41.971 -5.419 -27.170 1.00 12.26 ? 630 ARG A C 1 ATOM 4996 O O . ARG A 1 630 ? -41.864 -4.368 -27.820 1.00 12.91 ? 630 ARG A O 1 ATOM 4997 C CB . ARG A 1 630 ? -41.287 -5.694 -24.809 1.00 12.25 ? 630 ARG A CB 1 ATOM 4998 C CG . ARG A 1 630 ? -40.002 -4.848 -25.146 1.00 12.07 ? 630 ARG A CG 1 ATOM 4999 C CD . ARG A 1 630 ? -38.768 -5.465 -24.501 1.00 14.10 ? 630 ARG A CD 1 ATOM 5000 N NE . ARG A 1 630 ? -37.628 -4.556 -24.616 1.00 13.13 ? 630 ARG A NE 1 ATOM 5001 C CZ . ARG A 1 630 ? -37.397 -3.535 -23.775 1.00 17.02 ? 630 ARG A CZ 1 ATOM 5002 N NH1 . ARG A 1 630 ? -38.235 -3.287 -22.750 1.00 16.13 ? 630 ARG A NH1 1 ATOM 5003 N NH2 . ARG A 1 630 ? -36.340 -2.756 -23.946 1.00 16.25 ? 630 ARG A NH2 1 ATOM 5004 N N . TYR A 1 631 ? -41.683 -6.621 -27.695 1.00 12.94 ? 631 TYR A N 1 ATOM 5005 C CA . TYR A 1 631 ? -41.195 -6.755 -29.070 1.00 13.63 ? 631 TYR A CA 1 ATOM 5006 C C . TYR A 1 631 ? -42.186 -6.234 -30.124 1.00 13.38 ? 631 TYR A C 1 ATOM 5007 O O . TYR A 1 631 ? -41.823 -5.556 -31.063 1.00 14.45 ? 631 TYR A O 1 ATOM 5008 C CB . TYR A 1 631 ? -40.866 -8.219 -29.337 1.00 13.45 ? 631 TYR A CB 1 ATOM 5009 C CG . TYR A 1 631 ? -39.472 -8.587 -28.865 1.00 16.32 ? 631 TYR A CG 1 ATOM 5010 C CD1 . TYR A 1 631 ? -39.057 -8.340 -27.552 1.00 17.34 ? 631 TYR A CD1 1 ATOM 5011 C CD2 . TYR A 1 631 ? -38.552 -9.150 -29.756 1.00 17.58 ? 631 TYR A CD2 1 ATOM 5012 C CE1 . TYR A 1 631 ? -37.744 -8.680 -27.120 1.00 16.93 ? 631 TYR A CE1 1 ATOM 5013 C CE2 . TYR A 1 631 ? -37.230 -9.496 -29.326 1.00 18.92 ? 631 TYR A CE2 1 ATOM 5014 C CZ . TYR A 1 631 ? -36.850 -9.238 -28.035 1.00 17.76 ? 631 TYR A CZ 1 ATOM 5015 O OH . TYR A 1 631 ? -35.580 -9.599 -27.640 1.00 17.62 ? 631 TYR A OH 1 ATOM 5016 N N . THR A 1 632 ? -43.470 -6.493 -29.903 1.00 14.15 ? 632 THR A N 1 ATOM 5017 C CA . THR A 1 632 ? -44.515 -5.934 -30.782 1.00 14.72 ? 632 THR A CA 1 ATOM 5018 C C . THR A 1 632 ? -44.436 -4.415 -30.869 1.00 15.02 ? 632 THR A C 1 ATOM 5019 O O . THR A 1 632 ? -44.640 -3.826 -31.933 1.00 15.89 ? 632 THR A O 1 ATOM 5020 C CB . THR A 1 632 ? -45.925 -6.310 -30.224 1.00 15.07 ? 632 THR A CB 1 ATOM 5021 O OG1 . THR A 1 632 ? -46.041 -7.731 -30.096 1.00 16.54 ? 632 THR A OG1 1 ATOM 5022 C CG2 . THR A 1 632 ? -47.066 -5.767 -31.132 1.00 17.23 ? 632 THR A CG2 1 ATOM 5023 N N . LEU A 1 633 ? -44.139 -3.770 -29.741 1.00 14.53 ? 633 LEU A N 1 ATOM 5024 C CA . LEU A 1 633 ? -44.090 -2.299 -29.676 1.00 14.69 ? 633 LEU A CA 1 ATOM 5025 C C . LEU A 1 633 ? -42.701 -1.778 -29.933 1.00 14.72 ? 633 LEU A C 1 ATOM 5026 O O . LEU A 1 633 ? -42.474 -0.602 -29.775 1.00 14.63 ? 633 LEU A O 1 ATOM 5027 C CB . LEU A 1 633 ? -44.532 -1.774 -28.300 1.00 13.60 ? 633 LEU A CB 1 ATOM 5028 C CG . LEU A 1 633 ? -46.057 -2.033 -28.065 1.00 13.51 ? 633 LEU A CG 1 ATOM 5029 C CD1 . LEU A 1 633 ? -46.349 -1.839 -26.573 1.00 11.91 ? 633 LEU A CD1 1 ATOM 5030 C CD2 . LEU A 1 633 ? -46.782 -1.031 -28.900 1.00 16.40 ? 633 LEU A CD2 1 ATOM 5031 N N . LEU A 1 634 ? -41.797 -2.620 -30.398 1.00 16.05 ? 634 LEU A N 1 ATOM 5032 C CA . LEU A 1 634 ? -40.475 -2.098 -30.688 1.00 15.93 ? 634 LEU A CA 1 ATOM 5033 C C . LEU A 1 634 ? -40.384 -0.958 -31.729 1.00 15.66 ? 634 LEU A C 1 ATOM 5034 O O . LEU A 1 634 ? -39.489 -0.122 -31.607 1.00 17.23 ? 634 LEU A O 1 ATOM 5035 C CB . LEU A 1 634 ? -39.467 -3.223 -31.013 1.00 17.58 ? 634 LEU A CB 1 ATOM 5036 C CG . LEU A 1 634 ? -38.913 -4.079 -29.867 1.00 19.61 ? 634 LEU A CG 1 ATOM 5037 C CD1 . LEU A 1 634 ? -37.946 -5.128 -30.434 1.00 20.46 ? 634 LEU A CD1 1 ATOM 5038 C CD2 . LEU A 1 634 ? -38.224 -3.211 -28.777 1.00 19.66 ? 634 LEU A CD2 1 ATOM 5039 N N . PRO A 1 635 ? -41.211 -0.965 -32.802 1.00 14.01 ? 635 PRO A N 1 ATOM 5040 C CA . PRO A 1 635 ? -41.149 0.177 -33.697 1.00 14.52 ? 635 PRO A CA 1 ATOM 5041 C C . PRO A 1 635 ? -41.501 1.476 -32.969 1.00 13.96 ? 635 PRO A C 1 ATOM 5042 O O . PRO A 1 635 ? -40.936 2.471 -33.249 1.00 15.52 ? 635 PRO A O 1 ATOM 5043 C CB . PRO A 1 635 ? -42.217 -0.154 -34.768 1.00 15.46 ? 635 PRO A CB 1 ATOM 5044 C CG . PRO A 1 635 ? -42.204 -1.648 -34.807 1.00 13.44 ? 635 PRO A CG 1 ATOM 5045 C CD . PRO A 1 635 ? -42.138 -1.989 -33.331 1.00 14.52 ? 635 PRO A CD 1 ATOM 5046 N N . TYR A 1 636 ? -42.461 1.445 -32.049 1.00 12.81 ? 636 TYR A N 1 ATOM 5047 C CA . TYR A 1 636 ? -42.772 2.603 -31.216 1.00 13.03 ? 636 TYR A CA 1 ATOM 5048 C C . TYR A 1 636 ? -41.571 2.978 -30.302 1.00 13.27 ? 636 TYR A C 1 ATOM 5049 O O . TYR A 1 636 ? -41.074 4.129 -30.312 1.00 14.40 ? 636 TYR A O 1 ATOM 5050 C CB . TYR A 1 636 ? -44.039 2.255 -30.402 1.00 11.70 ? 636 TYR A CB 1 ATOM 5051 C CG . TYR A 1 636 ? -44.472 3.338 -29.421 1.00 14.14 ? 636 TYR A CG 1 ATOM 5052 C CD1 . TYR A 1 636 ? -44.820 4.617 -29.856 1.00 13.71 ? 636 TYR A CD1 1 ATOM 5053 C CD2 . TYR A 1 636 ? -44.545 3.061 -28.074 1.00 13.71 ? 636 TYR A CD2 1 ATOM 5054 C CE1 . TYR A 1 636 ? -45.206 5.616 -28.935 1.00 14.40 ? 636 TYR A CE1 1 ATOM 5055 C CE2 . TYR A 1 636 ? -44.927 4.033 -27.148 1.00 13.76 ? 636 TYR A CE2 1 ATOM 5056 C CZ . TYR A 1 636 ? -45.261 5.296 -27.583 1.00 12.20 ? 636 TYR A CZ 1 ATOM 5057 O OH . TYR A 1 636 ? -45.613 6.239 -26.625 1.00 13.34 ? 636 TYR A OH 1 ATOM 5058 N N . LEU A 1 637 ? -41.103 2.036 -29.508 1.00 13.51 ? 637 LEU A N 1 ATOM 5059 C CA . LEU A 1 637 ? -39.880 2.277 -28.683 1.00 13.63 ? 637 LEU A CA 1 ATOM 5060 C C . LEU A 1 637 ? -38.712 2.840 -29.478 1.00 13.69 ? 637 LEU A C 1 ATOM 5061 O O . LEU A 1 637 ? -38.092 3.792 -29.042 1.00 13.78 ? 637 LEU A O 1 ATOM 5062 C CB . LEU A 1 637 ? -39.474 1.012 -27.936 1.00 12.73 ? 637 LEU A CB 1 ATOM 5063 C CG . LEU A 1 637 ? -38.347 1.197 -26.895 1.00 13.86 ? 637 LEU A CG 1 ATOM 5064 C CD1 . LEU A 1 637 ? -38.750 2.204 -25.781 1.00 14.89 ? 637 LEU A CD1 1 ATOM 5065 C CD2 . LEU A 1 637 ? -37.997 -0.154 -26.352 1.00 13.52 ? 637 LEU A CD2 1 ATOM 5066 N N . TYR A 1 638 ? -38.420 2.259 -30.642 1.00 14.31 ? 638 TYR A N 1 ATOM 5067 C CA . TYR A 1 638 ? -37.334 2.731 -31.524 1.00 13.62 ? 638 TYR A CA 1 ATOM 5068 C C . TYR A 1 638 ? -37.526 4.166 -31.990 1.00 13.33 ? 638 TYR A C 1 ATOM 5069 O O . TYR A 1 638 ? -36.601 4.962 -32.006 1.00 12.95 ? 638 TYR A O 1 ATOM 5070 C CB . TYR A 1 638 ? -37.199 1.789 -32.743 1.00 14.18 ? 638 TYR A CB 1 ATOM 5071 C CG . TYR A 1 638 ? -35.917 1.959 -33.531 1.00 14.10 ? 638 TYR A CG 1 ATOM 5072 C CD1 . TYR A 1 638 ? -34.669 1.933 -32.890 1.00 14.68 ? 638 TYR A CD1 1 ATOM 5073 C CD2 . TYR A 1 638 ? -35.941 2.160 -34.895 1.00 10.51 ? 638 TYR A CD2 1 ATOM 5074 C CE1 . TYR A 1 638 ? -33.485 2.071 -33.618 1.00 15.35 ? 638 TYR A CE1 1 ATOM 5075 C CE2 . TYR A 1 638 ? -34.766 2.303 -35.638 1.00 13.59 ? 638 TYR A CE2 1 ATOM 5076 C CZ . TYR A 1 638 ? -33.543 2.258 -35.003 1.00 15.09 ? 638 TYR A CZ 1 ATOM 5077 O OH . TYR A 1 638 ? -32.348 2.378 -35.754 1.00 16.09 ? 638 TYR A OH 1 ATOM 5078 N N . THR A 1 639 ? -38.751 4.531 -32.344 1.00 11.79 ? 639 THR A N 1 ATOM 5079 C CA . THR A 1 639 ? -39.034 5.871 -32.758 1.00 11.36 ? 639 THR A CA 1 ATOM 5080 C C . THR A 1 639 ? -38.856 6.818 -31.546 1.00 11.20 ? 639 THR A C 1 ATOM 5081 O O . THR A 1 639 ? -38.435 7.951 -31.725 1.00 12.29 ? 639 THR A O 1 ATOM 5082 C CB . THR A 1 639 ? -40.520 5.966 -33.309 1.00 10.70 ? 639 THR A CB 1 ATOM 5083 O OG1 . THR A 1 639 ? -40.633 5.098 -34.445 1.00 13.01 ? 639 THR A OG1 1 ATOM 5084 C CG2 . THR A 1 639 ? -40.864 7.384 -33.733 1.00 13.50 ? 639 THR A CG2 1 ATOM 5085 N N . LEU A 1 640 ? -39.156 6.347 -30.336 1.00 10.80 ? 640 LEU A N 1 ATOM 5086 C CA . LEU A 1 640 ? -38.966 7.170 -29.131 1.00 11.08 ? 640 LEU A CA 1 ATOM 5087 C C . LEU A 1 640 ? -37.452 7.403 -28.954 1.00 11.49 ? 640 LEU A C 1 ATOM 5088 O O . LEU A 1 640 ? -37.031 8.502 -28.602 1.00 11.51 ? 640 LEU A O 1 ATOM 5089 C CB . LEU A 1 640 ? -39.513 6.503 -27.885 1.00 9.95 ? 640 LEU A CB 1 ATOM 5090 C CG . LEU A 1 640 ? -41.059 6.390 -27.830 1.00 10.32 ? 640 LEU A CG 1 ATOM 5091 C CD1 . LEU A 1 640 ? -41.365 5.731 -26.512 1.00 10.72 ? 640 LEU A CD1 1 ATOM 5092 C CD2 . LEU A 1 640 ? -41.618 7.771 -27.967 1.00 11.97 ? 640 LEU A CD2 1 ATOM 5093 N N . PHE A 1 641 ? -36.677 6.366 -29.169 1.00 12.22 ? 641 PHE A N 1 ATOM 5094 C CA . PHE A 1 641 ? -35.194 6.552 -29.159 1.00 14.12 ? 641 PHE A CA 1 ATOM 5095 C C . PHE A 1 641 ? -34.713 7.469 -30.263 1.00 13.24 ? 641 PHE A C 1 ATOM 5096 O O . PHE A 1 641 ? -33.746 8.213 -30.067 1.00 13.78 ? 641 PHE A O 1 ATOM 5097 C CB . PHE A 1 641 ? -34.444 5.221 -29.220 1.00 14.07 ? 641 PHE A CB 1 ATOM 5098 C CG . PHE A 1 641 ? -34.309 4.524 -27.871 1.00 15.88 ? 641 PHE A CG 1 ATOM 5099 C CD1 . PHE A 1 641 ? -33.279 4.903 -26.977 1.00 14.49 ? 641 PHE A CD1 1 ATOM 5100 C CD2 . PHE A 1 641 ? -35.194 3.533 -27.503 1.00 15.38 ? 641 PHE A CD2 1 ATOM 5101 C CE1 . PHE A 1 641 ? -33.139 4.266 -25.745 1.00 14.51 ? 641 PHE A CE1 1 ATOM 5102 C CE2 . PHE A 1 641 ? -35.070 2.874 -26.274 1.00 17.52 ? 641 PHE A CE2 1 ATOM 5103 C CZ . PHE A 1 641 ? -34.038 3.249 -25.378 1.00 16.60 ? 641 PHE A CZ 1 ATOM 5104 N N . PHE A 1 642 ? -35.342 7.420 -31.442 1.00 14.75 ? 642 PHE A N 1 ATOM 5105 C CA . PHE A 1 642 ? -35.012 8.381 -32.494 1.00 14.37 ? 642 PHE A CA 1 ATOM 5106 C C . PHE A 1 642 ? -35.233 9.833 -32.042 1.00 13.98 ? 642 PHE A C 1 ATOM 5107 O O . PHE A 1 642 ? -34.368 10.710 -32.240 1.00 14.67 ? 642 PHE A O 1 ATOM 5108 C CB . PHE A 1 642 ? -35.742 8.094 -33.819 1.00 13.98 ? 642 PHE A CB 1 ATOM 5109 C CG . PHE A 1 642 ? -35.797 9.259 -34.740 1.00 13.71 ? 642 PHE A CG 1 ATOM 5110 C CD1 . PHE A 1 642 ? -34.680 9.680 -35.451 1.00 12.28 ? 642 PHE A CD1 1 ATOM 5111 C CD2 . PHE A 1 642 ? -37.016 9.935 -34.942 1.00 14.24 ? 642 PHE A CD2 1 ATOM 5112 C CE1 . PHE A 1 642 ? -34.762 10.793 -36.339 1.00 15.11 ? 642 PHE A CE1 1 ATOM 5113 C CE2 . PHE A 1 642 ? -37.110 11.017 -35.818 1.00 12.61 ? 642 PHE A CE2 1 ATOM 5114 C CZ . PHE A 1 642 ? -35.980 11.472 -36.510 1.00 16.66 ? 642 PHE A CZ 1 ATOM 5115 N N . ARG A 1 643 ? -36.342 10.071 -31.362 1.00 14.15 ? 643 ARG A N 1 ATOM 5116 C CA . ARG A 1 643 ? -36.626 11.400 -30.875 1.00 13.48 ? 643 ARG A CA 1 ATOM 5117 C C . ARG A 1 643 ? -35.700 11.796 -29.743 1.00 13.33 ? 643 ARG A C 1 ATOM 5118 O O . ARG A 1 643 ? -35.316 12.954 -29.682 1.00 13.64 ? 643 ARG A O 1 ATOM 5119 C CB . ARG A 1 643 ? -38.089 11.545 -30.452 1.00 14.89 ? 643 ARG A CB 1 ATOM 5120 C CG . ARG A 1 643 ? -39.057 11.516 -31.648 1.00 13.44 ? 643 ARG A CG 1 ATOM 5121 C CD . ARG A 1 643 ? -38.744 12.579 -32.692 1.00 16.57 ? 643 ARG A CD 1 ATOM 5122 N NE . ARG A 1 643 ? -39.891 12.775 -33.601 1.00 24.27 ? 643 ARG A NE 1 ATOM 5123 C CZ . ARG A 1 643 ? -39.869 13.541 -34.690 1.00 26.84 ? 643 ARG A CZ 1 ATOM 5124 N NH1 . ARG A 1 643 ? -38.783 14.237 -35.000 1.00 26.36 ? 643 ARG A NH1 1 ATOM 5125 N NH2 . ARG A 1 643 ? -40.948 13.646 -35.459 1.00 24.24 ? 643 ARG A NH2 1 ATOM 5126 N N . ALA A 1 644 ? -35.314 10.852 -28.884 1.00 12.56 ? 644 ALA A N 1 ATOM 5127 C CA . ALA A 1 644 ? -34.302 11.188 -27.834 1.00 13.08 ? 644 ALA A CA 1 ATOM 5128 C C . ALA A 1 644 ? -32.990 11.601 -28.498 1.00 14.13 ? 644 ALA A C 1 ATOM 5129 O O . ALA A 1 644 ? -32.336 12.587 -28.100 1.00 15.58 ? 644 ALA A O 1 ATOM 5130 C CB . ALA A 1 644 ? -34.107 9.962 -26.876 1.00 11.44 ? 644 ALA A CB 1 ATOM 5131 N N . HIS A 1 645 ? -32.558 10.811 -29.476 1.00 14.37 ? 645 HIS A N 1 ATOM 5132 C CA . HIS A 1 645 ? -31.311 11.096 -30.190 1.00 14.18 ? 645 HIS A CA 1 ATOM 5133 C C . HIS A 1 645 ? -31.357 12.409 -30.983 1.00 14.40 ? 645 HIS A C 1 ATOM 5134 O O . HIS A 1 645 ? -30.370 13.123 -31.026 1.00 15.06 ? 645 HIS A O 1 ATOM 5135 C CB . HIS A 1 645 ? -30.965 9.927 -31.134 1.00 14.64 ? 645 HIS A CB 1 ATOM 5136 C CG . HIS A 1 645 ? -29.772 10.189 -32.013 1.00 15.97 ? 645 HIS A CG 1 ATOM 5137 N ND1 . HIS A 1 645 ? -28.478 10.203 -31.538 1.00 19.95 ? 645 HIS A ND1 1 ATOM 5138 C CD2 . HIS A 1 645 ? -29.687 10.448 -33.343 1.00 20.83 ? 645 HIS A CD2 1 ATOM 5139 C CE1 . HIS A 1 645 ? -27.640 10.466 -32.532 1.00 20.22 ? 645 HIS A CE1 1 ATOM 5140 N NE2 . HIS A 1 645 ? -28.348 10.621 -33.640 1.00 24.20 ? 645 HIS A NE2 1 ATOM 5141 N N . SER A 1 646 ? -32.479 12.708 -31.632 1.00 15.18 ? 646 SER A N 1 ATOM 5142 C CA . SER A 1 646 ? -32.516 13.790 -32.596 1.00 16.96 ? 646 SER A CA 1 ATOM 5143 C C . SER A 1 646 ? -33.047 15.091 -32.017 1.00 18.07 ? 646 SER A C 1 ATOM 5144 O O . SER A 1 646 ? -32.688 16.192 -32.468 1.00 18.47 ? 646 SER A O 1 ATOM 5145 C CB . SER A 1 646 ? -33.302 13.363 -33.840 1.00 17.49 ? 646 SER A CB 1 ATOM 5146 O OG . SER A 1 646 ? -34.669 13.120 -33.522 1.00 17.77 ? 646 SER A OG 1 ATOM 5147 N N . ARG A 1 647 ? -33.894 14.975 -31.004 1.00 16.96 ? 647 ARG A N 1 ATOM 5148 C CA . ARG A 1 647 ? -34.580 16.116 -30.463 1.00 17.44 ? 647 ARG A CA 1 ATOM 5149 C C . ARG A 1 647 ? -34.279 16.308 -28.968 1.00 16.44 ? 647 ARG A C 1 ATOM 5150 O O . ARG A 1 647 ? -34.295 17.430 -28.437 1.00 17.30 ? 647 ARG A O 1 ATOM 5151 C CB . ARG A 1 647 ? -36.095 15.931 -30.700 1.00 17.23 ? 647 ARG A CB 1 ATOM 5152 C CG . ARG A 1 647 ? -36.828 17.226 -30.535 1.00 21.74 ? 647 ARG A CG 1 ATOM 5153 C CD . ARG A 1 647 ? -38.216 17.153 -31.150 1.00 25.23 ? 647 ARG A CD 1 ATOM 5154 N NE . ARG A 1 647 ? -39.027 16.115 -30.554 1.00 22.41 ? 647 ARG A NE 1 ATOM 5155 C CZ . ARG A 1 647 ? -40.144 15.655 -31.114 1.00 24.27 ? 647 ARG A CZ 1 ATOM 5156 N NH1 . ARG A 1 647 ? -40.565 16.144 -32.283 1.00 24.31 ? 647 ARG A NH1 1 ATOM 5157 N NH2 . ARG A 1 647 ? -40.828 14.706 -30.520 1.00 23.77 ? 647 ARG A NH2 1 ATOM 5158 N N . GLY A 1 648 ? -34.009 15.206 -28.290 1.00 16.07 ? 648 GLY A N 1 ATOM 5159 C CA . GLY A 1 648 ? -33.706 15.207 -26.861 1.00 17.34 ? 648 GLY A CA 1 ATOM 5160 C C . GLY A 1 648 ? -34.854 14.816 -25.942 1.00 17.66 ? 648 GLY A C 1 ATOM 5161 O O . GLY A 1 648 ? -34.794 15.092 -24.757 1.00 18.31 ? 648 GLY A O 1 ATOM 5162 N N . ASP A 1 649 ? -35.901 14.211 -26.485 1.00 18.01 ? 649 ASP A N 1 ATOM 5163 C CA . ASP A 1 649 ? -37.058 13.723 -25.707 1.00 18.73 ? 649 ASP A CA 1 ATOM 5164 C C . ASP A 1 649 ? -36.659 12.595 -24.732 1.00 18.90 ? 649 ASP A C 1 ATOM 5165 O O . ASP A 1 649 ? -35.658 11.880 -24.979 1.00 19.31 ? 649 ASP A O 1 ATOM 5166 C CB . ASP A 1 649 ? -38.092 13.096 -26.673 1.00 19.68 ? 649 ASP A CB 1 ATOM 5167 C CG . ASP A 1 649 ? -38.719 14.097 -27.651 1.00 21.68 ? 649 ASP A CG 1 ATOM 5168 O OD1 . ASP A 1 649 ? -38.109 15.112 -28.013 1.00 21.22 ? 649 ASP A OD1 1 ATOM 5169 O OD2 . ASP A 1 649 ? -39.860 13.842 -28.109 1.00 25.64 ? 649 ASP A OD2 1 ATOM 5170 N N . THR A 1 650 ? -37.419 12.395 -23.645 1.00 16.56 ? 650 THR A N 1 ATOM 5171 C CA . THR A 1 650 ? -37.194 11.204 -22.795 1.00 15.26 ? 650 THR A CA 1 ATOM 5172 C C . THR A 1 650 ? -37.865 9.997 -23.498 1.00 15.42 ? 650 THR A C 1 ATOM 5173 O O . THR A 1 650 ? -38.751 10.179 -24.368 1.00 16.11 ? 650 THR A O 1 ATOM 5174 C CB . THR A 1 650 ? -37.798 11.380 -21.381 1.00 15.69 ? 650 THR A CB 1 ATOM 5175 O OG1 . THR A 1 650 ? -39.209 11.717 -21.526 1.00 15.38 ? 650 THR A OG1 1 ATOM 5176 C CG2 . THR A 1 650 ? -37.127 12.516 -20.650 1.00 16.56 ? 650 THR A CG2 1 ATOM 5177 N N . VAL A 1 651 ? -37.503 8.801 -23.068 1.00 13.82 ? 651 VAL A N 1 ATOM 5178 C CA . VAL A 1 651 ? -38.058 7.548 -23.594 1.00 12.84 ? 651 VAL A CA 1 ATOM 5179 C C . VAL A 1 651 ? -38.994 6.958 -22.536 1.00 13.01 ? 651 VAL A C 1 ATOM 5180 O O . VAL A 1 651 ? -40.231 6.972 -22.728 1.00 14.32 ? 651 VAL A O 1 ATOM 5181 C CB . VAL A 1 651 ? -36.888 6.582 -24.040 1.00 11.99 ? 651 VAL A CB 1 ATOM 5182 C CG1 . VAL A 1 651 ? -37.427 5.200 -24.404 1.00 10.45 ? 651 VAL A CG1 1 ATOM 5183 C CG2 . VAL A 1 651 ? -36.167 7.164 -25.230 1.00 11.54 ? 651 VAL A CG2 1 ATOM 5184 N N . ALA A 1 652 ? -38.442 6.460 -21.419 1.00 14.17 ? 652 ALA A N 1 ATOM 5185 C CA . ALA A 1 652 ? -39.183 6.250 -20.157 1.00 14.18 ? 652 ALA A CA 1 ATOM 5186 C C . ALA A 1 652 ? -39.416 7.636 -19.523 1.00 14.76 ? 652 ALA A C 1 ATOM 5187 O O . ALA A 1 652 ? -38.485 8.408 -19.234 1.00 14.83 ? 652 ALA A O 1 ATOM 5188 C CB . ALA A 1 652 ? -38.390 5.331 -19.174 1.00 13.22 ? 652 ALA A CB 1 ATOM 5189 N N . ARG A 1 653 ? -40.671 7.973 -19.326 1.00 14.86 ? 653 ARG A N 1 ATOM 5190 C CA . ARG A 1 653 ? -41.030 9.343 -19.097 1.00 15.00 ? 653 ARG A CA 1 ATOM 5191 C C . ARG A 1 653 ? -41.916 9.393 -17.874 1.00 14.15 ? 653 ARG A C 1 ATOM 5192 O O . ARG A 1 653 ? -42.787 8.524 -17.720 1.00 15.15 ? 653 ARG A O 1 ATOM 5193 C CB . ARG A 1 653 ? -41.804 9.839 -20.332 1.00 15.47 ? 653 ARG A CB 1 ATOM 5194 C CG . ARG A 1 653 ? -42.033 11.306 -20.314 1.00 15.75 ? 653 ARG A CG 1 ATOM 5195 C CD . ARG A 1 653 ? -42.703 11.742 -21.602 1.00 18.85 ? 653 ARG A CD 1 ATOM 5196 N NE . ARG A 1 653 ? -41.747 11.558 -22.704 1.00 16.38 ? 653 ARG A NE 1 ATOM 5197 C CZ . ARG A 1 653 ? -42.030 11.782 -23.979 1.00 19.26 ? 653 ARG A CZ 1 ATOM 5198 N NH1 . ARG A 1 653 ? -43.230 12.231 -24.352 1.00 12.61 ? 653 ARG A NH1 1 ATOM 5199 N NH2 . ARG A 1 653 ? -41.106 11.546 -24.893 1.00 17.17 ? 653 ARG A NH2 1 ATOM 5200 N N . PRO A 1 654 ? -41.723 10.407 -16.985 1.00 14.79 ? 654 PRO A N 1 ATOM 5201 C CA . PRO A 1 654 ? -42.666 10.529 -15.847 1.00 13.68 ? 654 PRO A CA 1 ATOM 5202 C C . PRO A 1 654 ? -44.048 10.885 -16.313 1.00 13.70 ? 654 PRO A C 1 ATOM 5203 O O . PRO A 1 654 ? -44.201 11.548 -17.331 1.00 14.52 ? 654 PRO A O 1 ATOM 5204 C CB . PRO A 1 654 ? -42.102 11.695 -15.040 1.00 14.28 ? 654 PRO A CB 1 ATOM 5205 C CG . PRO A 1 654 ? -40.560 11.757 -15.479 1.00 14.05 ? 654 PRO A CG 1 ATOM 5206 C CD . PRO A 1 654 ? -40.633 11.406 -16.931 1.00 12.81 ? 654 PRO A CD 1 ATOM 5207 N N . LEU A 1 655 ? -45.069 10.493 -15.561 1.00 13.53 ? 655 LEU A N 1 ATOM 5208 C CA . LEU A 1 655 ? -46.404 10.949 -15.884 1.00 14.79 ? 655 LEU A CA 1 ATOM 5209 C C . LEU A 1 655 ? -46.532 12.456 -15.972 1.00 14.00 ? 655 LEU A C 1 ATOM 5210 O O . LEU A 1 655 ? -47.250 12.964 -16.807 1.00 15.26 ? 655 LEU A O 1 ATOM 5211 C CB . LEU A 1 655 ? -47.421 10.421 -14.847 1.00 15.44 ? 655 LEU A CB 1 ATOM 5212 C CG . LEU A 1 655 ? -48.063 9.055 -15.167 1.00 16.15 ? 655 LEU A CG 1 ATOM 5213 C CD1 . LEU A 1 655 ? -47.064 7.924 -15.266 1.00 19.11 ? 655 LEU A CD1 1 ATOM 5214 C CD2 . LEU A 1 655 ? -49.161 8.724 -14.091 1.00 15.54 ? 655 LEU A CD2 1 ATOM 5215 N N . LEU A 1 656 ? -45.887 13.164 -15.051 1.00 13.53 ? 656 LEU A N 1 ATOM 5216 C CA . LEU A 1 656 ? -45.940 14.602 -14.978 1.00 13.50 ? 656 LEU A CA 1 ATOM 5217 C C . LEU A 1 656 ? -45.347 15.292 -16.214 1.00 13.54 ? 656 LEU A C 1 ATOM 5218 O O . LEU A 1 656 ? -45.628 16.449 -16.436 1.00 13.22 ? 656 LEU A O 1 ATOM 5219 C CB . LEU A 1 656 ? -45.222 15.065 -13.695 1.00 13.91 ? 656 LEU A CB 1 ATOM 5220 C CG . LEU A 1 656 ? -43.700 14.995 -13.703 1.00 15.65 ? 656 LEU A CG 1 ATOM 5221 C CD1 . LEU A 1 656 ? -43.112 16.407 -13.981 1.00 17.58 ? 656 LEU A CD1 1 ATOM 5222 C CD2 . LEU A 1 656 ? -43.180 14.473 -12.367 1.00 18.01 ? 656 LEU A CD2 1 ATOM 5223 N N . HIS A 1 657 ? -44.477 14.632 -17.007 1.00 14.95 ? 657 HIS A N 1 ATOM 5224 C CA . HIS A 1 657 ? -44.014 15.271 -18.260 1.00 13.59 ? 657 HIS A CA 1 ATOM 5225 C C . HIS A 1 657 ? -45.131 15.435 -19.297 1.00 15.32 ? 657 HIS A C 1 ATOM 5226 O O . HIS A 1 657 ? -45.097 16.331 -20.136 1.00 15.57 ? 657 HIS A O 1 ATOM 5227 C CB . HIS A 1 657 ? -42.857 14.512 -18.869 1.00 14.66 ? 657 HIS A CB 1 ATOM 5228 C CG . HIS A 1 657 ? -41.567 14.742 -18.124 1.00 9.95 ? 657 HIS A CG 1 ATOM 5229 N ND1 . HIS A 1 657 ? -40.331 14.758 -18.747 1.00 13.46 ? 657 HIS A ND1 1 ATOM 5230 C CD2 . HIS A 1 657 ? -41.338 15.033 -16.824 1.00 11.32 ? 657 HIS A CD2 1 ATOM 5231 C CE1 . HIS A 1 657 ? -39.386 15.012 -17.852 1.00 11.77 ? 657 HIS A CE1 1 ATOM 5232 N NE2 . HIS A 1 657 ? -39.958 15.189 -16.679 1.00 13.02 ? 657 HIS A NE2 1 ATOM 5233 N N . GLU A 1 658 ? -46.133 14.580 -19.193 1.00 14.46 ? 658 GLU A N 1 ATOM 5234 C CA . GLU A 1 658 ? -47.293 14.684 -20.078 1.00 15.18 ? 658 GLU A CA 1 ATOM 5235 C C . GLU A 1 658 ? -48.502 15.285 -19.389 1.00 16.60 ? 658 GLU A C 1 ATOM 5236 O O . GLU A 1 658 ? -49.395 15.817 -20.048 1.00 17.81 ? 658 GLU A O 1 ATOM 5237 C CB . GLU A 1 658 ? -47.669 13.312 -20.582 1.00 14.70 ? 658 GLU A CB 1 ATOM 5238 C CG . GLU A 1 658 ? -46.641 12.679 -21.547 1.00 16.31 ? 658 GLU A CG 1 ATOM 5239 C CD . GLU A 1 658 ? -46.445 13.481 -22.813 1.00 19.78 ? 658 GLU A CD 1 ATOM 5240 O OE1 . GLU A 1 658 ? -47.456 13.884 -23.447 1.00 21.01 ? 658 GLU A OE1 1 ATOM 5241 O OE2 . GLU A 1 658 ? -45.262 13.685 -23.190 1.00 19.43 ? 658 GLU A OE2 1 ATOM 5242 N N . PHE A 1 659 ? -48.551 15.167 -18.078 1.00 15.95 ? 659 PHE A N 1 ATOM 5243 C CA . PHE A 1 659 ? -49.768 15.514 -17.348 1.00 16.23 ? 659 PHE A CA 1 ATOM 5244 C C . PHE A 1 659 ? -49.477 16.544 -16.244 1.00 16.41 ? 659 PHE A C 1 ATOM 5245 O O . PHE A 1 659 ? -50.073 16.501 -15.168 1.00 15.63 ? 659 PHE A O 1 ATOM 5246 C CB . PHE A 1 659 ? -50.398 14.230 -16.814 1.00 15.32 ? 659 PHE A CB 1 ATOM 5247 C CG . PHE A 1 659 ? -50.788 13.263 -17.914 1.00 16.50 ? 659 PHE A CG 1 ATOM 5248 C CD1 . PHE A 1 659 ? -51.848 13.563 -18.759 1.00 16.97 ? 659 PHE A CD1 1 ATOM 5249 C CD2 . PHE A 1 659 ? -50.061 12.084 -18.129 1.00 14.95 ? 659 PHE A CD2 1 ATOM 5250 C CE1 . PHE A 1 659 ? -52.237 12.681 -19.815 1.00 15.14 ? 659 PHE A CE1 1 ATOM 5251 C CE2 . PHE A 1 659 ? -50.450 11.192 -19.161 1.00 15.07 ? 659 PHE A CE2 1 ATOM 5252 C CZ . PHE A 1 659 ? -51.555 11.524 -20.008 1.00 14.09 ? 659 PHE A CZ 1 ATOM 5253 N N . TYR A 1 660 ? -48.550 17.469 -16.538 1.00 16.78 ? 660 TYR A N 1 ATOM 5254 C CA . TYR A 1 660 ? -48.064 18.494 -15.557 1.00 17.88 ? 660 TYR A CA 1 ATOM 5255 C C . TYR A 1 660 ? -49.189 19.396 -15.080 1.00 17.62 ? 660 TYR A C 1 ATOM 5256 O O . TYR A 1 660 ? -49.069 19.957 -14.019 1.00 18.00 ? 660 TYR A O 1 ATOM 5257 C CB . TYR A 1 660 ? -46.940 19.367 -16.140 1.00 16.71 ? 660 TYR A CB 1 ATOM 5258 C CG . TYR A 1 660 ? -47.199 19.761 -17.568 1.00 16.80 ? 660 TYR A CG 1 ATOM 5259 C CD1 . TYR A 1 660 ? -48.014 20.832 -17.890 1.00 14.51 ? 660 TYR A CD1 1 ATOM 5260 C CD2 . TYR A 1 660 ? -46.627 19.022 -18.629 1.00 18.46 ? 660 TYR A CD2 1 ATOM 5261 C CE1 . TYR A 1 660 ? -48.274 21.166 -19.234 1.00 17.35 ? 660 TYR A CE1 1 ATOM 5262 C CE2 . TYR A 1 660 ? -46.879 19.335 -19.933 1.00 18.50 ? 660 TYR A CE2 1 ATOM 5263 C CZ . TYR A 1 660 ? -47.700 20.407 -20.234 1.00 20.86 ? 660 TYR A CZ 1 ATOM 5264 O OH . TYR A 1 660 ? -47.907 20.681 -21.563 1.00 23.02 ? 660 TYR A OH 1 ATOM 5265 N N . GLU A 1 661 ? -50.284 19.534 -15.856 1.00 18.54 ? 661 GLU A N 1 ATOM 5266 C CA A GLU A 1 661 ? -51.463 20.314 -15.465 0.50 18.98 ? 661 GLU A CA 1 ATOM 5267 C CA B GLU A 1 661 ? -51.414 20.367 -15.416 0.50 19.28 ? 661 GLU A CA 1 ATOM 5268 C C . GLU A 1 661 ? -52.136 19.741 -14.232 1.00 19.47 ? 661 GLU A C 1 ATOM 5269 O O . GLU A 1 661 ? -52.921 20.419 -13.545 1.00 19.75 ? 661 GLU A O 1 ATOM 5270 C CB A GLU A 1 661 ? -52.496 20.330 -16.611 0.50 18.98 ? 661 GLU A CB 1 ATOM 5271 C CB B GLU A 1 661 ? -52.407 20.679 -16.569 0.50 18.81 ? 661 GLU A CB 1 ATOM 5272 C CG A GLU A 1 661 ? -51.958 20.773 -17.987 0.50 20.22 ? 661 GLU A CG 1 ATOM 5273 C CG B GLU A 1 661 ? -51.900 21.736 -17.588 0.50 19.20 ? 661 GLU A CG 1 ATOM 5274 C CD A GLU A 1 661 ? -51.453 19.625 -18.895 0.50 24.18 ? 661 GLU A CD 1 ATOM 5275 C CD B GLU A 1 661 ? -52.753 21.882 -18.865 0.50 21.85 ? 661 GLU A CD 1 ATOM 5276 O OE1 A GLU A 1 661 ? -51.164 18.477 -18.426 0.50 19.35 ? 661 GLU A OE1 1 ATOM 5277 O OE1 B GLU A 1 661 ? -53.989 21.625 -18.830 0.50 25.88 ? 661 GLU A OE1 1 ATOM 5278 O OE2 A GLU A 1 661 ? -51.317 19.912 -20.108 0.50 26.19 ? 661 GLU A OE2 1 ATOM 5279 O OE2 B GLU A 1 661 ? -52.194 22.278 -19.918 0.50 24.45 ? 661 GLU A OE2 1 ATOM 5280 N N . ASP A 1 662 ? -51.856 18.470 -13.975 1.00 18.73 ? 662 ASP A N 1 ATOM 5281 C CA . ASP A 1 662 ? -52.524 17.707 -12.934 1.00 18.84 ? 662 ASP A CA 1 ATOM 5282 C C . ASP A 1 662 ? -51.556 17.439 -11.811 1.00 19.60 ? 662 ASP A C 1 ATOM 5283 O O . ASP A 1 662 ? -50.730 16.545 -11.918 1.00 17.28 ? 662 ASP A O 1 ATOM 5284 C CB . ASP A 1 662 ? -53.052 16.403 -13.573 1.00 17.99 ? 662 ASP A CB 1 ATOM 5285 C CG . ASP A 1 662 ? -53.820 15.496 -12.598 1.00 20.66 ? 662 ASP A CG 1 ATOM 5286 O OD1 . ASP A 1 662 ? -53.969 15.823 -11.407 1.00 20.78 ? 662 ASP A OD1 1 ATOM 5287 O OD2 . ASP A 1 662 ? -54.321 14.440 -13.063 1.00 22.09 ? 662 ASP A OD2 1 ATOM 5288 N N . ASN A 1 663 ? -51.688 18.189 -10.706 1.00 19.43 ? 663 ASN A N 1 ATOM 5289 C CA . ASN A 1 663 ? -50.773 18.025 -9.583 1.00 19.86 ? 663 ASN A CA 1 ATOM 5290 C C . ASN A 1 663 ? -50.745 16.624 -8.929 1.00 19.19 ? 663 ASN A C 1 ATOM 5291 O O . ASN A 1 663 ? -49.736 16.278 -8.280 1.00 18.53 ? 663 ASN A O 1 ATOM 5292 C CB . ASN A 1 663 ? -50.992 19.122 -8.519 1.00 19.95 ? 663 ASN A CB 1 ATOM 5293 C CG . ASN A 1 663 ? -52.248 18.900 -7.720 1.00 24.30 ? 663 ASN A CG 1 ATOM 5294 O OD1 . ASN A 1 663 ? -53.264 18.408 -8.234 1.00 26.37 ? 663 ASN A OD1 1 ATOM 5295 N ND2 . ASN A 1 663 ? -52.194 19.263 -6.453 1.00 29.62 ? 663 ASN A ND2 1 ATOM 5296 N N . SER A 1 664 ? -51.795 15.797 -9.132 1.00 19.87 ? 664 SER A N 1 ATOM 5297 C CA . SER A 1 664 ? -51.747 14.406 -8.663 1.00 20.23 ? 664 SER A CA 1 ATOM 5298 C C . SER A 1 664 ? -50.642 13.578 -9.346 1.00 19.63 ? 664 SER A C 1 ATOM 5299 O O . SER A 1 664 ? -50.301 12.501 -8.855 1.00 20.60 ? 664 SER A O 1 ATOM 5300 C CB . SER A 1 664 ? -53.079 13.656 -8.853 1.00 21.80 ? 664 SER A CB 1 ATOM 5301 O OG . SER A 1 664 ? -54.148 14.355 -8.248 1.00 21.67 ? 664 SER A OG 1 ATOM 5302 N N . THR A 1 665 ? -50.086 14.070 -10.448 1.00 18.44 ? 665 THR A N 1 ATOM 5303 C CA . THR A 1 665 ? -49.010 13.336 -11.125 1.00 16.93 ? 665 THR A CA 1 ATOM 5304 C C . THR A 1 665 ? -47.588 13.728 -10.668 1.00 17.54 ? 665 THR A C 1 ATOM 5305 O O . THR A 1 665 ? -46.640 13.057 -11.032 1.00 16.61 ? 665 THR A O 1 ATOM 5306 C CB . THR A 1 665 ? -49.060 13.499 -12.620 1.00 16.90 ? 665 THR A CB 1 ATOM 5307 O OG1 . THR A 1 665 ? -48.758 14.859 -12.977 1.00 18.03 ? 665 THR A OG1 1 ATOM 5308 C CG2 . THR A 1 665 ? -50.434 13.063 -13.201 1.00 15.86 ? 665 THR A CG2 1 ATOM 5309 N N . TRP A 1 666 ? -47.454 14.805 -9.896 1.00 16.66 ? 666 TRP A N 1 ATOM 5310 C CA . TRP A 1 666 ? -46.142 15.400 -9.618 1.00 18.35 ? 666 TRP A CA 1 ATOM 5311 C C . TRP A 1 666 ? -45.261 14.517 -8.745 1.00 18.28 ? 666 TRP A C 1 ATOM 5312 O O . TRP A 1 666 ? -44.041 14.656 -8.737 1.00 19.22 ? 666 TRP A O 1 ATOM 5313 C CB . TRP A 1 666 ? -46.320 16.784 -8.971 1.00 18.22 ? 666 TRP A CB 1 ATOM 5314 C CG . TRP A 1 666 ? -46.976 17.847 -9.852 1.00 19.50 ? 666 TRP A CG 1 ATOM 5315 C CD1 . TRP A 1 666 ? -47.333 17.740 -11.165 1.00 18.52 ? 666 TRP A CD1 1 ATOM 5316 C CD2 . TRP A 1 666 ? -47.311 19.182 -9.448 1.00 20.68 ? 666 TRP A CD2 1 ATOM 5317 N NE1 . TRP A 1 666 ? -47.893 18.935 -11.613 1.00 18.99 ? 666 TRP A NE1 1 ATOM 5318 C CE2 . TRP A 1 666 ? -47.882 19.838 -10.576 1.00 19.03 ? 666 TRP A CE2 1 ATOM 5319 C CE3 . TRP A 1 666 ? -47.201 19.885 -8.233 1.00 22.43 ? 666 TRP A CE3 1 ATOM 5320 C CZ2 . TRP A 1 666 ? -48.331 21.173 -10.527 1.00 21.36 ? 666 TRP A CZ2 1 ATOM 5321 C CZ3 . TRP A 1 666 ? -47.654 21.237 -8.184 1.00 20.27 ? 666 TRP A CZ3 1 ATOM 5322 C CH2 . TRP A 1 666 ? -48.199 21.858 -9.330 1.00 20.69 ? 666 TRP A CH2 1 ATOM 5323 N N . ASP A 1 667 ? -45.867 13.597 -8.006 1.00 19.19 ? 667 ASP A N 1 ATOM 5324 C CA . ASP A 1 667 ? -45.057 12.714 -7.191 1.00 22.16 ? 667 ASP A CA 1 ATOM 5325 C C . ASP A 1 667 ? -45.174 11.239 -7.598 1.00 21.35 ? 667 ASP A C 1 ATOM 5326 O O . ASP A 1 667 ? -44.642 10.364 -6.919 1.00 22.38 ? 667 ASP A O 1 ATOM 5327 C CB . ASP A 1 667 ? -45.392 12.894 -5.718 1.00 24.18 ? 667 ASP A CB 1 ATOM 5328 C CG . ASP A 1 667 ? -46.849 12.668 -5.441 1.00 31.38 ? 667 ASP A CG 1 ATOM 5329 O OD1 . ASP A 1 667 ? -47.602 12.274 -6.391 1.00 38.14 ? 667 ASP A OD1 1 ATOM 5330 O OD2 . ASP A 1 667 ? -47.246 12.918 -4.276 1.00 40.94 ? 667 ASP A OD2 1 ATOM 5331 N N . VAL A 1 668 ? -45.858 10.970 -8.702 1.00 20.35 ? 668 VAL A N 1 ATOM 5332 C CA . VAL A 1 668 ? -46.053 9.589 -9.160 1.00 19.64 ? 668 VAL A CA 1 ATOM 5333 C C . VAL A 1 668 ? -44.726 8.977 -9.607 1.00 19.76 ? 668 VAL A C 1 ATOM 5334 O O . VAL A 1 668 ? -44.092 9.501 -10.508 1.00 19.66 ? 668 VAL A O 1 ATOM 5335 C CB . VAL A 1 668 ? -47.111 9.481 -10.264 1.00 19.45 ? 668 VAL A CB 1 ATOM 5336 C CG1 . VAL A 1 668 ? -47.032 8.142 -10.916 1.00 19.34 ? 668 VAL A CG1 1 ATOM 5337 C CG2 . VAL A 1 668 ? -48.504 9.708 -9.671 1.00 20.26 ? 668 VAL A CG2 1 ATOM 5338 N N . HIS A 1 669 ? -44.300 7.901 -8.934 1.00 19.92 ? 669 HIS A N 1 ATOM 5339 C CA . HIS A 1 669 ? -43.049 7.200 -9.273 1.00 21.61 ? 669 HIS A CA 1 ATOM 5340 C C . HIS A 1 669 ? -43.248 5.668 -9.276 1.00 21.33 ? 669 HIS A C 1 ATOM 5341 O O . HIS A 1 669 ? -42.278 4.934 -9.389 1.00 20.82 ? 669 HIS A O 1 ATOM 5342 C CB . HIS A 1 669 ? -41.918 7.577 -8.281 1.00 21.20 ? 669 HIS A CB 1 ATOM 5343 C CG . HIS A 1 669 ? -42.228 7.232 -6.864 1.00 25.37 ? 669 HIS A CG 1 ATOM 5344 N ND1 . HIS A 1 669 ? -41.826 6.051 -6.284 1.00 30.09 ? 669 HIS A ND1 1 ATOM 5345 C CD2 . HIS A 1 669 ? -42.977 7.867 -5.934 1.00 29.95 ? 669 HIS A CD2 1 ATOM 5346 C CE1 . HIS A 1 669 ? -42.270 5.995 -5.044 1.00 30.56 ? 669 HIS A CE1 1 ATOM 5347 N NE2 . HIS A 1 669 ? -42.967 7.087 -4.802 1.00 30.69 ? 669 HIS A NE2 1 ATOM 5348 N N . GLN A 1 670 ? -44.494 5.209 -9.129 1.00 20.26 ? 670 GLN A N 1 ATOM 5349 C CA . GLN A 1 670 ? -44.831 3.787 -9.163 1.00 21.73 ? 670 GLN A CA 1 ATOM 5350 C C . GLN A 1 670 ? -45.433 3.358 -10.514 1.00 18.81 ? 670 GLN A C 1 ATOM 5351 O O . GLN A 1 670 ? -45.757 2.192 -10.715 1.00 18.26 ? 670 GLN A O 1 ATOM 5352 C CB . GLN A 1 670 ? -45.808 3.432 -8.031 1.00 21.77 ? 670 GLN A CB 1 ATOM 5353 C CG . GLN A 1 670 ? -45.118 3.326 -6.645 1.00 26.10 ? 670 GLN A CG 1 ATOM 5354 C CD . GLN A 1 670 ? -45.974 2.511 -5.634 1.00 28.56 ? 670 GLN A CD 1 ATOM 5355 O OE1 . GLN A 1 670 ? -45.441 1.771 -4.778 1.00 36.42 ? 670 GLN A OE1 1 ATOM 5356 N NE2 . GLN A 1 670 ? -47.305 2.611 -5.771 1.00 34.08 ? 670 GLN A NE2 1 ATOM 5357 N N . GLN A 1 671 ? -45.545 4.326 -11.423 1.00 16.51 ? 671 GLN A N 1 ATOM 5358 C CA . GLN A 1 671 ? -45.980 4.119 -12.774 1.00 16.18 ? 671 GLN A CA 1 ATOM 5359 C C . GLN A 1 671 ? -45.105 5.014 -13.625 1.00 15.48 ? 671 GLN A C 1 ATOM 5360 O O . GLN A 1 671 ? -44.494 5.955 -13.110 1.00 16.79 ? 671 GLN A O 1 ATOM 5361 C CB . GLN A 1 671 ? -47.420 4.621 -12.942 1.00 15.49 ? 671 GLN A CB 1 ATOM 5362 C CG . GLN A 1 671 ? -48.459 3.847 -12.193 1.00 19.51 ? 671 GLN A CG 1 ATOM 5363 C CD . GLN A 1 671 ? -49.786 4.588 -12.209 1.00 18.53 ? 671 GLN A CD 1 ATOM 5364 O OE1 . GLN A 1 671 ? -50.037 5.453 -11.372 1.00 19.66 ? 671 GLN A OE1 1 ATOM 5365 N NE2 . GLN A 1 671 ? -50.608 4.287 -13.187 1.00 22.98 ? 671 GLN A NE2 1 ATOM 5366 N N . PHE A 1 672 ? -45.001 4.680 -14.903 1.00 15.37 ? 672 PHE A N 1 ATOM 5367 C CA . PHE A 1 672 ? -44.372 5.539 -15.886 1.00 15.64 ? 672 PHE A CA 1 ATOM 5368 C C . PHE A 1 672 ? -44.944 5.318 -17.281 1.00 15.47 ? 672 PHE A C 1 ATOM 5369 O O . PHE A 1 672 ? -45.764 4.419 -17.482 1.00 15.78 ? 672 PHE A O 1 ATOM 5370 C CB . PHE A 1 672 ? -42.833 5.356 -15.861 1.00 15.92 ? 672 PHE A CB 1 ATOM 5371 C CG . PHE A 1 672 ? -42.360 3.994 -16.300 1.00 18.85 ? 672 PHE A CG 1 ATOM 5372 C CD1 . PHE A 1 672 ? -41.694 3.837 -17.519 1.00 20.83 ? 672 PHE A CD1 1 ATOM 5373 C CD2 . PHE A 1 672 ? -42.508 2.880 -15.474 1.00 19.57 ? 672 PHE A CD2 1 ATOM 5374 C CE1 . PHE A 1 672 ? -41.254 2.588 -17.940 1.00 19.40 ? 672 PHE A CE1 1 ATOM 5375 C CE2 . PHE A 1 672 ? -42.065 1.620 -15.883 1.00 21.81 ? 672 PHE A CE2 1 ATOM 5376 C CZ . PHE A 1 672 ? -41.425 1.474 -17.119 1.00 18.16 ? 672 PHE A CZ 1 ATOM 5377 N N . LEU A 1 673 ? -44.514 6.147 -18.232 1.00 14.70 ? 673 LEU A N 1 ATOM 5378 C CA . LEU A 1 673 ? -44.926 6.054 -19.611 1.00 15.50 ? 673 LEU A CA 1 ATOM 5379 C C . LEU A 1 673 ? -43.789 5.599 -20.500 1.00 16.66 ? 673 LEU A C 1 ATOM 5380 O O . LEU A 1 673 ? -42.620 5.909 -20.217 1.00 15.66 ? 673 LEU A O 1 ATOM 5381 C CB . LEU A 1 673 ? -45.300 7.439 -20.088 1.00 16.08 ? 673 LEU A CB 1 ATOM 5382 C CG . LEU A 1 673 ? -46.337 8.190 -19.249 1.00 18.05 ? 673 LEU A CG 1 ATOM 5383 C CD1 . LEU A 1 673 ? -46.336 9.609 -19.786 1.00 18.02 ? 673 LEU A CD1 1 ATOM 5384 C CD2 . LEU A 1 673 ? -47.698 7.543 -19.426 1.00 21.07 ? 673 LEU A CD2 1 ATOM 5385 N N . TRP A 1 674 ? -44.117 4.884 -21.564 1.00 16.06 ? 674 TRP A N 1 ATOM 5386 C CA . TRP A 1 674 ? -43.219 4.921 -22.718 1.00 16.02 ? 674 TRP A CA 1 ATOM 5387 C C . TRP A 1 674 ? -43.621 6.089 -23.578 1.00 16.68 ? 674 TRP A C 1 ATOM 5388 O O . TRP A 1 674 ? -44.750 6.068 -24.129 1.00 16.06 ? 674 TRP A O 1 ATOM 5389 C CB . TRP A 1 674 ? -43.403 3.664 -23.543 1.00 17.00 ? 674 TRP A CB 1 ATOM 5390 C CG . TRP A 1 674 ? -42.577 2.497 -23.138 1.00 17.65 ? 674 TRP A CG 1 ATOM 5391 C CD1 . TRP A 1 674 ? -41.912 2.293 -21.952 1.00 20.37 ? 674 TRP A CD1 1 ATOM 5392 C CD2 . TRP A 1 674 ? -42.338 1.347 -23.941 1.00 18.54 ? 674 TRP A CD2 1 ATOM 5393 N NE1 . TRP A 1 674 ? -41.257 1.083 -21.986 1.00 20.76 ? 674 TRP A NE1 1 ATOM 5394 C CE2 . TRP A 1 674 ? -41.504 0.479 -23.191 1.00 19.67 ? 674 TRP A CE2 1 ATOM 5395 C CE3 . TRP A 1 674 ? -42.737 0.971 -25.242 1.00 16.71 ? 674 TRP A CE3 1 ATOM 5396 C CZ2 . TRP A 1 674 ? -41.056 -0.744 -23.693 1.00 19.31 ? 674 TRP A CZ2 1 ATOM 5397 C CZ3 . TRP A 1 674 ? -42.298 -0.248 -25.735 1.00 17.06 ? 674 TRP A CZ3 1 ATOM 5398 C CH2 . TRP A 1 674 ? -41.477 -1.098 -24.952 1.00 18.64 ? 674 TRP A CH2 1 ATOM 5399 N N . GLY A 1 675 ? -42.734 7.078 -23.738 1.00 14.90 ? 675 GLY A N 1 ATOM 5400 C CA . GLY A 1 675 ? -43.061 8.263 -24.567 1.00 14.98 ? 675 GLY A CA 1 ATOM 5401 C C . GLY A 1 675 ? -44.389 8.878 -24.069 1.00 15.33 ? 675 GLY A C 1 ATOM 5402 O O . GLY A 1 675 ? -44.627 8.901 -22.868 1.00 14.06 ? 675 GLY A O 1 ATOM 5403 N N . PRO A 1 676 ? -45.213 9.422 -24.978 1.00 15.74 ? 676 PRO A N 1 ATOM 5404 C CA . PRO A 1 676 ? -46.457 10.082 -24.528 1.00 17.36 ? 676 PRO A CA 1 ATOM 5405 C C . PRO A 1 676 ? -47.653 9.172 -24.303 1.00 17.93 ? 676 PRO A C 1 ATOM 5406 O O . PRO A 1 676 ? -48.596 9.581 -23.599 1.00 19.12 ? 676 PRO A O 1 ATOM 5407 C CB . PRO A 1 676 ? -46.745 11.069 -25.659 1.00 17.00 ? 676 PRO A CB 1 ATOM 5408 C CG . PRO A 1 676 ? -46.177 10.309 -26.923 1.00 17.81 ? 676 PRO A CG 1 ATOM 5409 C CD . PRO A 1 676 ? -44.968 9.580 -26.428 1.00 15.44 ? 676 PRO A CD 1 ATOM 5410 N N . GLY A 1 677 ? -47.622 7.945 -24.828 1.00 18.24 ? 677 GLY A N 1 ATOM 5411 C CA . GLY A 1 677 ? -48.894 7.226 -25.093 1.00 18.94 ? 677 GLY A CA 1 ATOM 5412 C C . GLY A 1 677 ? -49.163 5.919 -24.374 1.00 18.53 ? 677 GLY A C 1 ATOM 5413 O O . GLY A 1 677 ? -50.301 5.444 -24.379 1.00 19.36 ? 677 GLY A O 1 ATOM 5414 N N . LEU A 1 678 ? -48.135 5.319 -23.775 1.00 17.76 ? 678 LEU A N 1 ATOM 5415 C CA . LEU A 1 678 ? -48.281 3.996 -23.101 1.00 17.43 ? 678 LEU A CA 1 ATOM 5416 C C . LEU A 1 678 ? -48.011 4.108 -21.614 1.00 17.58 ? 678 LEU A C 1 ATOM 5417 O O . LEU A 1 678 ? -46.887 4.424 -21.199 1.00 16.27 ? 678 LEU A O 1 ATOM 5418 C CB . LEU A 1 678 ? -47.327 2.938 -23.704 1.00 16.83 ? 678 LEU A CB 1 ATOM 5419 C CG . LEU A 1 678 ? -47.271 1.552 -23.017 1.00 16.94 ? 678 LEU A CG 1 ATOM 5420 C CD1 . LEU A 1 678 ? -48.590 0.761 -23.262 1.00 18.57 ? 678 LEU A CD1 1 ATOM 5421 C CD2 . LEU A 1 678 ? -46.115 0.716 -23.492 1.00 17.31 ? 678 LEU A CD2 1 ATOM 5422 N N . LEU A 1 679 ? -49.025 3.801 -20.810 1.00 16.45 ? 679 LEU A N 1 ATOM 5423 C CA . LEU A 1 679 ? -48.962 3.903 -19.362 1.00 16.07 ? 679 LEU A CA 1 ATOM 5424 C C . LEU A 1 679 ? -48.695 2.510 -18.798 1.00 15.50 ? 679 LEU A C 1 ATOM 5425 O O . LEU A 1 679 ? -49.437 1.565 -19.065 1.00 14.60 ? 679 LEU A O 1 ATOM 5426 C CB . LEU A 1 679 ? -50.332 4.408 -18.852 1.00 15.54 ? 679 LEU A CB 1 ATOM 5427 C CG . LEU A 1 679 ? -50.520 4.503 -17.348 1.00 14.45 ? 679 LEU A CG 1 ATOM 5428 C CD1 . LEU A 1 679 ? -49.490 5.464 -16.690 1.00 16.01 ? 679 LEU A CD1 1 ATOM 5429 C CD2 . LEU A 1 679 ? -51.977 4.903 -17.020 1.00 17.48 ? 679 LEU A CD2 1 ATOM 5430 N N . ILE A 1 680 ? -47.610 2.372 -18.049 1.00 14.34 ? 680 ILE A N 1 ATOM 5431 C CA . ILE A 1 680 ? -47.238 1.109 -17.433 1.00 14.16 ? 680 ILE A CA 1 ATOM 5432 C C . ILE A 1 680 ? -47.521 1.173 -15.932 1.00 14.58 ? 680 ILE A C 1 ATOM 5433 O O . ILE A 1 680 ? -46.994 2.044 -15.221 1.00 16.58 ? 680 ILE A O 1 ATOM 5434 C CB . ILE A 1 680 ? -45.686 0.796 -17.699 1.00 14.86 ? 680 ILE A CB 1 ATOM 5435 C CG1 . ILE A 1 680 ? -45.439 0.655 -19.209 1.00 17.07 ? 680 ILE A CG1 1 ATOM 5436 C CG2 . ILE A 1 680 ? -45.258 -0.509 -16.992 1.00 15.76 ? 680 ILE A CG2 1 ATOM 5437 C CD1 . ILE A 1 680 ? -44.313 1.527 -19.707 1.00 23.23 ? 680 ILE A CD1 1 ATOM 5438 N N . THR A 1 681 ? -48.248 0.183 -15.420 1.00 14.10 ? 681 THR A N 1 ATOM 5439 C CA . THR A 1 681 ? -48.689 0.165 -14.018 1.00 14.49 ? 681 THR A CA 1 ATOM 5440 C C . THR A 1 681 ? -48.418 -1.203 -13.446 1.00 14.44 ? 681 THR A C 1 ATOM 5441 O O . THR A 1 681 ? -49.238 -2.133 -13.538 1.00 15.46 ? 681 THR A O 1 ATOM 5442 C CB . THR A 1 681 ? -50.241 0.483 -13.907 1.00 12.67 ? 681 THR A CB 1 ATOM 5443 O OG1 . THR A 1 681 ? -50.449 1.761 -14.479 1.00 17.93 ? 681 THR A OG1 1 ATOM 5444 C CG2 . THR A 1 681 ? -50.660 0.579 -12.445 1.00 15.33 ? 681 THR A CG2 1 ATOM 5445 N N . PRO A 1 682 ? -47.222 -1.377 -12.875 1.00 14.65 ? 682 PRO A N 1 ATOM 5446 C CA . PRO A 1 682 ? -46.832 -2.622 -12.235 1.00 14.87 ? 682 PRO A CA 1 ATOM 5447 C C . PRO A 1 682 ? -47.375 -2.855 -10.833 1.00 15.38 ? 682 PRO A C 1 ATOM 5448 O O . PRO A 1 682 ? -47.667 -1.901 -10.080 1.00 15.99 ? 682 PRO A O 1 ATOM 5449 C CB . PRO A 1 682 ? -45.304 -2.478 -12.127 1.00 14.36 ? 682 PRO A CB 1 ATOM 5450 C CG . PRO A 1 682 ? -45.122 -0.984 -11.934 1.00 13.65 ? 682 PRO A CG 1 ATOM 5451 C CD . PRO A 1 682 ? -46.143 -0.372 -12.870 1.00 14.58 ? 682 PRO A CD 1 ATOM 5452 N N . VAL A 1 683 ? -47.488 -4.134 -10.486 1.00 17.27 ? 683 VAL A N 1 ATOM 5453 C CA . VAL A 1 683 ? -47.647 -4.539 -9.100 1.00 18.61 ? 683 VAL A CA 1 ATOM 5454 C C . VAL A 1 683 ? -46.274 -4.518 -8.452 1.00 20.06 ? 683 VAL A C 1 ATOM 5455 O O . VAL A 1 683 ? -45.340 -5.129 -8.964 1.00 19.61 ? 683 VAL A O 1 ATOM 5456 C CB . VAL A 1 683 ? -48.293 -5.912 -9.005 1.00 18.75 ? 683 VAL A CB 1 ATOM 5457 C CG1 . VAL A 1 683 ? -48.215 -6.454 -7.564 1.00 20.23 ? 683 VAL A CG1 1 ATOM 5458 C CG2 . VAL A 1 683 ? -49.743 -5.800 -9.469 1.00 19.48 ? 683 VAL A CG2 1 ATOM 5459 N N . LEU A 1 684 ? -46.149 -3.774 -7.355 1.00 20.21 ? 684 LEU A N 1 ATOM 5460 C CA . LEU A 1 684 ? -44.833 -3.553 -6.737 1.00 22.44 ? 684 LEU A CA 1 ATOM 5461 C C . LEU A 1 684 ? -44.795 -4.015 -5.279 1.00 23.22 ? 684 LEU A C 1 ATOM 5462 O O . LEU A 1 684 ? -43.843 -3.719 -4.569 1.00 22.84 ? 684 LEU A O 1 ATOM 5463 C CB . LEU A 1 684 ? -44.465 -2.070 -6.809 1.00 21.40 ? 684 LEU A CB 1 ATOM 5464 C CG . LEU A 1 684 ? -44.422 -1.562 -8.234 1.00 20.96 ? 684 LEU A CG 1 ATOM 5465 C CD1 . LEU A 1 684 ? -44.257 -0.053 -8.230 1.00 22.39 ? 684 LEU A CD1 1 ATOM 5466 C CD2 . LEU A 1 684 ? -43.299 -2.254 -8.984 1.00 21.94 ? 684 LEU A CD2 1 ATOM 5467 N N . ASP A 1 685 ? -45.854 -4.706 -4.840 1.00 24.80 ? 685 ASP A N 1 ATOM 5468 C CA . ASP A 1 685 ? -45.965 -5.136 -3.432 1.00 25.77 ? 685 ASP A CA 1 ATOM 5469 C C . ASP A 1 685 ? -46.182 -6.637 -3.274 1.00 25.79 ? 685 ASP A C 1 ATOM 5470 O O . ASP A 1 685 ? -46.980 -7.242 -3.982 1.00 23.34 ? 685 ASP A O 1 ATOM 5471 C CB . ASP A 1 685 ? -47.064 -4.369 -2.723 1.00 27.93 ? 685 ASP A CB 1 ATOM 5472 C CG . ASP A 1 685 ? -46.771 -2.888 -2.636 1.00 31.74 ? 685 ASP A CG 1 ATOM 5473 O OD1 . ASP A 1 685 ? -45.797 -2.488 -1.950 1.00 37.22 ? 685 ASP A OD1 1 ATOM 5474 O OD2 . ASP A 1 685 ? -47.506 -2.114 -3.278 1.00 37.27 ? 685 ASP A OD2 1 ATOM 5475 N N . GLU A 1 686 ? -45.419 -7.228 -2.356 1.00 26.10 ? 686 GLU A N 1 ATOM 5476 C CA . GLU A 1 686 ? -45.500 -8.646 -2.065 1.00 27.04 ? 686 GLU A CA 1 ATOM 5477 C C . GLU A 1 686 ? -46.922 -9.072 -1.754 1.00 26.98 ? 686 GLU A C 1 ATOM 5478 O O . GLU A 1 686 ? -47.594 -8.459 -0.916 1.00 26.63 ? 686 GLU A O 1 ATOM 5479 C CB . GLU A 1 686 ? -44.603 -9.004 -0.892 1.00 27.18 ? 686 GLU A CB 1 ATOM 5480 C CG . GLU A 1 686 ? -44.347 -10.479 -0.819 1.00 29.65 ? 686 GLU A CG 1 ATOM 5481 C CD . GLU A 1 686 ? -43.371 -10.857 0.270 1.00 34.94 ? 686 GLU A CD 1 ATOM 5482 O OE1 . GLU A 1 686 ? -42.508 -10.032 0.603 1.00 34.88 ? 686 GLU A OE1 1 ATOM 5483 O OE2 . GLU A 1 686 ? -43.481 -11.987 0.810 1.00 39.91 ? 686 GLU A OE2 1 ATOM 5484 N N . GLY A 1 687 ? -47.375 -10.107 -2.449 1.00 26.68 ? 687 GLY A N 1 ATOM 5485 C CA . GLY A 1 687 ? -48.677 -10.697 -2.163 1.00 27.31 ? 687 GLY A CA 1 ATOM 5486 C C . GLY A 1 687 ? -49.817 -10.018 -2.864 1.00 27.75 ? 687 GLY A C 1 ATOM 5487 O O . GLY A 1 687 ? -50.926 -10.518 -2.829 1.00 28.07 ? 687 GLY A O 1 ATOM 5488 N N . ALA A 1 688 ? -49.543 -8.893 -3.526 1.00 27.35 ? 688 ALA A N 1 ATOM 5489 C CA . ALA A 1 688 ? -50.594 -8.099 -4.152 1.00 27.27 ? 688 ALA A CA 1 ATOM 5490 C C . ALA A 1 688 ? -51.077 -8.637 -5.497 1.00 27.66 ? 688 ALA A C 1 ATOM 5491 O O . ALA A 1 688 ? -50.289 -9.130 -6.297 1.00 26.12 ? 688 ALA A O 1 ATOM 5492 C CB . ALA A 1 688 ? -50.158 -6.597 -4.273 1.00 27.42 ? 688 ALA A CB 1 ATOM 5493 N N . GLU A 1 689 ? -52.394 -8.536 -5.719 1.00 28.23 ? 689 GLU A N 1 ATOM 5494 C CA . GLU A 1 689 ? -53.031 -8.816 -7.012 1.00 29.97 ? 689 GLU A CA 1 ATOM 5495 C C . GLU A 1 689 ? -53.875 -7.587 -7.427 1.00 28.89 ? 689 GLU A C 1 ATOM 5496 O O . GLU A 1 689 ? -54.879 -7.666 -8.173 1.00 27.38 ? 689 GLU A O 1 ATOM 5497 C CB . GLU A 1 689 ? -53.824 -10.135 -6.971 1.00 30.21 ? 689 GLU A CB 1 ATOM 5498 C CG . GLU A 1 689 ? -52.916 -11.387 -6.939 1.00 32.81 ? 689 GLU A CG 1 ATOM 5499 C CD . GLU A 1 689 ? -53.627 -12.678 -7.375 1.00 35.75 ? 689 GLU A CD 1 ATOM 5500 O OE1 . GLU A 1 689 ? -54.734 -12.928 -6.827 1.00 39.19 ? 689 GLU A OE1 1 ATOM 5501 O OE2 . GLU A 1 689 ? -53.093 -13.429 -8.278 1.00 41.46 ? 689 GLU A OE2 1 ATOM 5502 N N . LYS A 1 690 ? -53.426 -6.450 -6.910 1.00 29.17 ? 690 LYS A N 1 ATOM 5503 C CA . LYS A 1 690 ? -54.016 -5.139 -7.113 1.00 30.71 ? 690 LYS A CA 1 ATOM 5504 C C . LYS A 1 690 ? -52.880 -4.155 -7.065 1.00 30.57 ? 690 LYS A C 1 ATOM 5505 O O . LYS A 1 690 ? -51.811 -4.453 -6.503 1.00 31.44 ? 690 LYS A O 1 ATOM 5506 C CB . LYS A 1 690 ? -54.941 -4.759 -5.958 1.00 31.11 ? 690 LYS A CB 1 ATOM 5507 C CG . LYS A 1 690 ? -56.311 -5.379 -6.007 1.00 35.41 ? 690 LYS A CG 1 ATOM 5508 C CD . LYS A 1 690 ? -56.972 -5.256 -4.650 1.00 40.19 ? 690 LYS A CD 1 ATOM 5509 C CE . LYS A 1 690 ? -58.293 -6.027 -4.601 1.00 44.14 ? 690 LYS A CE 1 ATOM 5510 N NZ . LYS A 1 690 ? -59.125 -5.583 -3.416 1.00 45.12 ? 690 LYS A NZ 1 ATOM 5511 N N . VAL A 1 691 ? -53.100 -2.986 -7.653 1.00 30.11 ? 691 VAL A N 1 ATOM 5512 C CA . VAL A 1 691 ? -52.216 -1.872 -7.424 1.00 31.18 ? 691 VAL A CA 1 ATOM 5513 C C . VAL A 1 691 ? -53.036 -0.587 -7.352 1.00 30.24 ? 691 VAL A C 1 ATOM 5514 O O . VAL A 1 691 ? -53.988 -0.397 -8.127 1.00 29.42 ? 691 VAL A O 1 ATOM 5515 C CB . VAL A 1 691 ? -51.146 -1.812 -8.495 1.00 30.83 ? 691 VAL A CB 1 ATOM 5516 C CG1 . VAL A 1 691 ? -51.705 -1.231 -9.761 1.00 34.08 ? 691 VAL A CG1 1 ATOM 5517 C CG2 . VAL A 1 691 ? -49.990 -0.989 -8.018 1.00 35.14 ? 691 VAL A CG2 1 ATOM 5518 N N . MET A 1 692 ? -52.704 0.238 -6.359 1.00 30.13 ? 692 MET A N 1 ATOM 5519 C CA . MET A 1 692 ? -53.250 1.589 -6.240 1.00 30.54 ? 692 MET A CA 1 ATOM 5520 C C . MET A 1 692 ? -52.482 2.402 -7.283 1.00 28.83 ? 692 MET A C 1 ATOM 5521 O O . MET A 1 692 ? -51.260 2.490 -7.231 1.00 29.03 ? 692 MET A O 1 ATOM 5522 C CB . MET A 1 692 ? -53.080 2.158 -4.817 1.00 32.18 ? 692 MET A CB 1 ATOM 5523 C CG . MET A 1 692 ? -54.079 1.579 -3.775 1.00 36.45 ? 692 MET A CG 1 ATOM 5524 S SD . MET A 1 692 ? -55.822 1.996 -4.150 1.00 48.78 ? 692 MET A SD 1 ATOM 5525 C CE . MET A 1 692 ? -56.739 1.251 -2.773 1.00 42.34 ? 692 MET A CE 1 ATOM 5526 N N . ALA A 1 693 ? -53.210 2.932 -8.250 1.00 27.04 ? 693 ALA A N 1 ATOM 5527 C CA . ALA A 1 693 ? -52.600 3.598 -9.402 1.00 25.36 ? 693 ALA A CA 1 ATOM 5528 C C . ALA A 1 693 ? -53.287 4.910 -9.671 1.00 24.34 ? 693 ALA A C 1 ATOM 5529 O O . ALA A 1 693 ? -54.476 5.073 -9.381 1.00 24.84 ? 693 ALA A O 1 ATOM 5530 C CB . ALA A 1 693 ? -52.724 2.708 -10.637 1.00 24.78 ? 693 ALA A CB 1 ATOM 5531 N N . TYR A 1 694 ? -52.566 5.815 -10.310 1.00 22.43 ? 694 TYR A N 1 ATOM 5532 C CA . TYR A 1 694 ? -53.185 7.018 -10.823 1.00 20.98 ? 694 TYR A CA 1 ATOM 5533 C C . TYR A 1 694 ? -53.510 6.910 -12.333 1.00 20.50 ? 694 TYR A C 1 ATOM 5534 O O . TYR A 1 694 ? -52.673 6.505 -13.151 1.00 20.61 ? 694 TYR A O 1 ATOM 5535 C CB . TYR A 1 694 ? -52.371 8.277 -10.466 1.00 21.12 ? 694 TYR A CB 1 ATOM 5536 C CG . TYR A 1 694 ? -53.169 9.520 -10.755 1.00 21.92 ? 694 TYR A CG 1 ATOM 5537 C CD1 . TYR A 1 694 ? -54.238 9.870 -9.934 1.00 22.51 ? 694 TYR A CD1 1 ATOM 5538 C CD2 . TYR A 1 694 ? -52.890 10.323 -11.859 1.00 21.31 ? 694 TYR A CD2 1 ATOM 5539 C CE1 . TYR A 1 694 ? -55.006 10.986 -10.201 1.00 21.49 ? 694 TYR A CE1 1 ATOM 5540 C CE2 . TYR A 1 694 ? -53.647 11.457 -12.136 1.00 22.00 ? 694 TYR A CE2 1 ATOM 5541 C CZ . TYR A 1 694 ? -54.702 11.777 -11.290 1.00 21.67 ? 694 TYR A CZ 1 ATOM 5542 O OH . TYR A 1 694 ? -55.468 12.877 -11.536 1.00 21.84 ? 694 TYR A OH 1 ATOM 5543 N N . VAL A 1 695 ? -54.755 7.204 -12.690 1.00 17.84 ? 695 VAL A N 1 ATOM 5544 C CA . VAL A 1 695 ? -55.139 7.283 -14.090 1.00 17.99 ? 695 VAL A CA 1 ATOM 5545 C C . VAL A 1 695 ? -55.242 8.766 -14.512 1.00 18.02 ? 695 VAL A C 1 ATOM 5546 O O . VAL A 1 695 ? -56.133 9.511 -14.042 1.00 17.81 ? 695 VAL A O 1 ATOM 5547 C CB . VAL A 1 695 ? -56.479 6.532 -14.332 1.00 18.37 ? 695 VAL A CB 1 ATOM 5548 C CG1 . VAL A 1 695 ? -56.886 6.633 -15.771 1.00 16.77 ? 695 VAL A CG1 1 ATOM 5549 C CG2 . VAL A 1 695 ? -56.386 5.078 -13.861 1.00 19.58 ? 695 VAL A CG2 1 ATOM 5550 N N . PRO A 1 696 ? -54.291 9.239 -15.346 1.00 17.52 ? 696 PRO A N 1 ATOM 5551 C CA . PRO A 1 696 ? -54.289 10.637 -15.779 1.00 17.32 ? 696 PRO A CA 1 ATOM 5552 C C . PRO A 1 696 ? -55.533 11.069 -16.601 1.00 18.00 ? 696 PRO A C 1 ATOM 5553 O O . PRO A 1 696 ? -56.318 10.234 -17.050 1.00 17.66 ? 696 PRO A O 1 ATOM 5554 C CB . PRO A 1 696 ? -53.011 10.734 -16.625 1.00 17.63 ? 696 PRO A CB 1 ATOM 5555 C CG . PRO A 1 696 ? -52.096 9.630 -16.073 1.00 16.55 ? 696 PRO A CG 1 ATOM 5556 C CD . PRO A 1 696 ? -53.106 8.498 -15.843 1.00 17.53 ? 696 PRO A CD 1 ATOM 5557 N N . ASP A 1 697 ? -55.625 12.374 -16.813 1.00 18.88 ? 697 ASP A N 1 ATOM 5558 C CA . ASP A 1 697 ? -56.670 13.066 -17.554 1.00 19.89 ? 697 ASP A CA 1 ATOM 5559 C C . ASP A 1 697 ? -56.556 12.818 -19.057 1.00 20.44 ? 697 ASP A C 1 ATOM 5560 O O . ASP A 1 697 ? -56.095 13.676 -19.835 1.00 20.56 ? 697 ASP A O 1 ATOM 5561 C CB . ASP A 1 697 ? -56.586 14.558 -17.227 1.00 20.56 ? 697 ASP A CB 1 ATOM 5562 C CG . ASP A 1 697 ? -57.809 15.348 -17.686 1.00 24.82 ? 697 ASP A CG 1 ATOM 5563 O OD1 . ASP A 1 697 ? -58.786 14.759 -18.220 1.00 26.82 ? 697 ASP A OD1 1 ATOM 5564 O OD2 . ASP A 1 697 ? -57.779 16.586 -17.505 1.00 27.47 ? 697 ASP A OD2 1 ATOM 5565 N N . ALA A 1 698 ? -56.999 11.631 -19.470 1.00 19.22 ? 698 ALA A N 1 ATOM 5566 C CA . ALA A 1 698 ? -56.976 11.258 -20.875 1.00 18.51 ? 698 ALA A CA 1 ATOM 5567 C C . ALA A 1 698 ? -57.938 10.130 -21.021 1.00 17.50 ? 698 ALA A C 1 ATOM 5568 O O . ALA A 1 698 ? -58.306 9.483 -20.036 1.00 17.35 ? 698 ALA A O 1 ATOM 5569 C CB . ALA A 1 698 ? -55.542 10.771 -21.309 1.00 16.98 ? 698 ALA A CB 1 ATOM 5570 N N . VAL A 1 699 ? -58.291 9.856 -22.263 1.00 17.93 ? 699 VAL A N 1 ATOM 5571 C CA . VAL A 1 699 ? -58.984 8.609 -22.613 1.00 18.69 ? 699 VAL A CA 1 ATOM 5572 C C . VAL A 1 699 ? -57.931 7.488 -22.537 1.00 18.84 ? 699 VAL A C 1 ATOM 5573 O O . VAL A 1 699 ? -56.828 7.679 -23.042 1.00 18.14 ? 699 VAL A O 1 ATOM 5574 C CB . VAL A 1 699 ? -59.551 8.695 -24.050 1.00 18.87 ? 699 VAL A CB 1 ATOM 5575 C CG1 . VAL A 1 699 ? -59.980 7.327 -24.532 1.00 20.83 ? 699 VAL A CG1 1 ATOM 5576 C CG2 . VAL A 1 699 ? -60.697 9.695 -24.127 1.00 21.20 ? 699 VAL A CG2 1 ATOM 5577 N N . TRP A 1 700 ? -58.215 6.377 -21.857 1.00 16.97 ? 700 TRP A N 1 ATOM 5578 C CA . TRP A 1 700 ? -57.270 5.244 -21.850 1.00 18.08 ? 700 TRP A CA 1 ATOM 5579 C C . TRP A 1 700 ? -57.934 3.943 -22.285 1.00 18.39 ? 700 TRP A C 1 ATOM 5580 O O . TRP A 1 700 ? -59.093 3.678 -21.937 1.00 19.30 ? 700 TRP A O 1 ATOM 5581 C CB . TRP A 1 700 ? -56.655 5.006 -20.470 1.00 16.87 ? 700 TRP A CB 1 ATOM 5582 C CG . TRP A 1 700 ? -55.892 6.167 -19.934 1.00 18.09 ? 700 TRP A CG 1 ATOM 5583 C CD1 . TRP A 1 700 ? -56.357 7.143 -19.105 1.00 17.54 ? 700 TRP A CD1 1 ATOM 5584 C CD2 . TRP A 1 700 ? -54.518 6.480 -20.203 1.00 15.63 ? 700 TRP A CD2 1 ATOM 5585 N NE1 . TRP A 1 700 ? -55.366 8.057 -18.837 1.00 17.17 ? 700 TRP A NE1 1 ATOM 5586 C CE2 . TRP A 1 700 ? -54.229 7.684 -19.516 1.00 17.39 ? 700 TRP A CE2 1 ATOM 5587 C CE3 . TRP A 1 700 ? -53.517 5.868 -20.986 1.00 16.35 ? 700 TRP A CE3 1 ATOM 5588 C CZ2 . TRP A 1 700 ? -52.960 8.278 -19.540 1.00 19.11 ? 700 TRP A CZ2 1 ATOM 5589 C CZ3 . TRP A 1 700 ? -52.251 6.463 -21.039 1.00 15.28 ? 700 TRP A CZ3 1 ATOM 5590 C CH2 . TRP A 1 700 ? -51.988 7.673 -20.322 1.00 16.56 ? 700 TRP A CH2 1 ATOM 5591 N N . TYR A 1 701 ? -57.169 3.110 -22.984 1.00 17.67 ? 701 TYR A N 1 ATOM 5592 C CA . TYR A 1 701 ? -57.626 1.796 -23.435 1.00 17.10 ? 701 TYR A CA 1 ATOM 5593 C C . TYR A 1 701 ? -56.733 0.697 -22.892 1.00 18.40 ? 701 TYR A C 1 ATOM 5594 O O . TYR A 1 701 ? -55.502 0.803 -22.952 1.00 15.88 ? 701 TYR A O 1 ATOM 5595 C CB . TYR A 1 701 ? -57.563 1.754 -24.954 1.00 17.16 ? 701 TYR A CB 1 ATOM 5596 C CG . TYR A 1 701 ? -58.369 2.827 -25.666 1.00 17.45 ? 701 TYR A CG 1 ATOM 5597 C CD1 . TYR A 1 701 ? -59.742 2.636 -25.891 1.00 18.54 ? 701 TYR A CD1 1 ATOM 5598 C CD2 . TYR A 1 701 ? -57.769 4.018 -26.127 1.00 17.03 ? 701 TYR A CD2 1 ATOM 5599 C CE1 . TYR A 1 701 ? -60.492 3.585 -26.548 1.00 17.31 ? 701 TYR A CE1 1 ATOM 5600 C CE2 . TYR A 1 701 ? -58.526 5.020 -26.788 1.00 18.12 ? 701 TYR A CE2 1 ATOM 5601 C CZ . TYR A 1 701 ? -59.913 4.769 -26.982 1.00 16.87 ? 701 TYR A CZ 1 ATOM 5602 O OH . TYR A 1 701 ? -60.735 5.672 -27.628 1.00 18.01 ? 701 TYR A OH 1 ATOM 5603 N N . ASP A 1 702 ? -57.334 -0.362 -22.371 1.00 18.20 ? 702 ASP A N 1 ATOM 5604 C CA . ASP A 1 702 ? -56.598 -1.594 -22.055 1.00 19.25 ? 702 ASP A CA 1 ATOM 5605 C C . ASP A 1 702 ? -55.838 -2.128 -23.281 1.00 19.37 ? 702 ASP A C 1 ATOM 5606 O O . ASP A 1 702 ? -56.419 -2.356 -24.373 1.00 17.53 ? 702 ASP A O 1 ATOM 5607 C CB . ASP A 1 702 ? -57.565 -2.649 -21.497 1.00 21.07 ? 702 ASP A CB 1 ATOM 5608 C CG . ASP A 1 702 ? -56.852 -3.882 -21.070 1.00 25.22 ? 702 ASP A CG 1 ATOM 5609 O OD1 . ASP A 1 702 ? -56.580 -3.979 -19.871 1.00 32.53 ? 702 ASP A OD1 1 ATOM 5610 O OD2 . ASP A 1 702 ? -56.501 -4.715 -21.935 1.00 28.53 ? 702 ASP A OD2 1 ATOM 5611 N N . TYR A 1 703 ? -54.515 -2.287 -23.138 1.00 18.81 ? 703 TYR A N 1 ATOM 5612 C CA . TYR A 1 703 ? -53.702 -2.663 -24.274 1.00 20.23 ? 703 TYR A CA 1 ATOM 5613 C C . TYR A 1 703 ? -54.164 -3.988 -24.901 1.00 22.36 ? 703 TYR A C 1 ATOM 5614 O O . TYR A 1 703 ? -54.258 -4.104 -26.123 1.00 23.53 ? 703 TYR A O 1 ATOM 5615 C CB . TYR A 1 703 ? -52.201 -2.737 -23.892 1.00 20.25 ? 703 TYR A CB 1 ATOM 5616 C CG . TYR A 1 703 ? -51.391 -3.310 -25.021 1.00 21.53 ? 703 TYR A CG 1 ATOM 5617 C CD1 . TYR A 1 703 ? -50.848 -2.478 -25.994 1.00 19.08 ? 703 TYR A CD1 1 ATOM 5618 C CD2 . TYR A 1 703 ? -51.210 -4.698 -25.148 1.00 20.97 ? 703 TYR A CD2 1 ATOM 5619 C CE1 . TYR A 1 703 ? -50.124 -3.004 -27.071 1.00 19.87 ? 703 TYR A CE1 1 ATOM 5620 C CE2 . TYR A 1 703 ? -50.501 -5.233 -26.212 1.00 21.82 ? 703 TYR A CE2 1 ATOM 5621 C CZ . TYR A 1 703 ? -49.951 -4.371 -27.160 1.00 21.26 ? 703 TYR A CZ 1 ATOM 5622 O OH . TYR A 1 703 ? -49.234 -4.873 -28.214 1.00 24.59 ? 703 TYR A OH 1 ATOM 5623 N N . GLU A 1 704 ? -54.461 -4.983 -24.077 1.00 23.70 ? 704 GLU A N 1 ATOM 5624 C CA . GLU A 1 704 ? -54.756 -6.310 -24.614 1.00 25.37 ? 704 GLU A CA 1 ATOM 5625 C C . GLU A 1 704 ? -56.147 -6.460 -25.210 1.00 24.33 ? 704 GLU A C 1 ATOM 5626 O O . GLU A 1 704 ? -56.291 -7.028 -26.278 1.00 25.23 ? 704 GLU A O 1 ATOM 5627 C CB . GLU A 1 704 ? -54.514 -7.377 -23.569 1.00 25.65 ? 704 GLU A CB 1 ATOM 5628 C CG . GLU A 1 704 ? -53.000 -7.569 -23.385 1.00 31.92 ? 704 GLU A CG 1 ATOM 5629 C CD . GLU A 1 704 ? -52.659 -8.894 -22.787 1.00 37.59 ? 704 GLU A CD 1 ATOM 5630 O OE1 . GLU A 1 704 ? -52.890 -9.947 -23.462 1.00 40.38 ? 704 GLU A OE1 1 ATOM 5631 O OE2 . GLU A 1 704 ? -52.152 -8.873 -21.643 1.00 38.73 ? 704 GLU A OE2 1 ATOM 5632 N N . THR A 1 705 ? -57.154 -5.950 -24.514 1.00 24.26 ? 705 THR A N 1 ATOM 5633 C CA . THR A 1 705 ? -58.533 -6.054 -24.998 1.00 23.29 ? 705 THR A CA 1 ATOM 5634 C C . THR A 1 705 ? -58.895 -4.890 -25.904 1.00 22.94 ? 705 THR A C 1 ATOM 5635 O O . THR A 1 705 ? -59.769 -5.013 -26.766 1.00 22.28 ? 705 THR A O 1 ATOM 5636 C CB . THR A 1 705 ? -59.527 -6.106 -23.839 1.00 23.35 ? 705 THR A CB 1 ATOM 5637 O OG1 . THR A 1 705 ? -59.480 -4.887 -23.124 1.00 23.29 ? 705 THR A OG1 1 ATOM 5638 C CG2 . THR A 1 705 ? -59.204 -7.206 -22.856 1.00 26.93 ? 705 THR A CG2 1 ATOM 5639 N N . GLY A 1 706 ? -58.237 -3.747 -25.717 1.00 20.66 ? 706 GLY A N 1 ATOM 5640 C CA . GLY A 1 706 ? -58.590 -2.554 -26.442 1.00 20.15 ? 706 GLY A CA 1 ATOM 5641 C C . GLY A 1 706 ? -59.796 -1.826 -25.843 1.00 20.47 ? 706 GLY A C 1 ATOM 5642 O O . GLY A 1 706 ? -60.210 -0.794 -26.367 1.00 19.02 ? 706 GLY A O 1 ATOM 5643 N N . SER A 1 707 ? -60.343 -2.303 -24.732 1.00 21.09 ? 707 SER A N 1 ATOM 5644 C CA . SER A 1 707 ? -61.515 -1.577 -24.220 1.00 22.19 ? 707 SER A CA 1 ATOM 5645 C C . SER A 1 707 ? -61.166 -0.299 -23.475 1.00 22.33 ? 707 SER A C 1 ATOM 5646 O O . SER A 1 707 ? -60.143 -0.220 -22.770 1.00 20.08 ? 707 SER A O 1 ATOM 5647 C CB . SER A 1 707 ? -62.444 -2.461 -23.403 1.00 23.76 ? 707 SER A CB 1 ATOM 5648 O OG . SER A 1 707 ? -61.940 -2.669 -22.127 1.00 30.24 ? 707 SER A OG 1 ATOM 5649 N N . GLN A 1 708 ? -62.015 0.709 -23.653 1.00 22.17 ? 708 GLN A N 1 ATOM 5650 C CA . GLN A 1 708 ? -61.844 1.981 -22.983 1.00 23.95 ? 708 GLN A CA 1 ATOM 5651 C C . GLN A 1 708 ? -62.130 1.856 -21.485 1.00 24.78 ? 708 GLN A C 1 ATOM 5652 O O . GLN A 1 708 ? -63.166 1.347 -21.089 1.00 26.49 ? 708 GLN A O 1 ATOM 5653 C CB . GLN A 1 708 ? -62.735 3.030 -23.621 1.00 23.72 ? 708 GLN A CB 1 ATOM 5654 C CG . GLN A 1 708 ? -62.479 4.426 -23.093 1.00 24.45 ? 708 GLN A CG 1 ATOM 5655 C CD . GLN A 1 708 ? -63.383 5.479 -23.745 1.00 27.71 ? 708 GLN A CD 1 ATOM 5656 O OE1 . GLN A 1 708 ? -63.895 5.285 -24.839 1.00 27.20 ? 708 GLN A OE1 1 ATOM 5657 N NE2 . GLN A 1 708 ? -63.531 6.621 -23.082 1.00 28.14 ? 708 GLN A NE2 1 ATOM 5658 N N . VAL A 1 709 ? -61.203 2.288 -20.645 1.00 24.19 ? 709 VAL A N 1 ATOM 5659 C CA . VAL A 1 709 ? -61.427 2.207 -19.206 1.00 24.88 ? 709 VAL A CA 1 ATOM 5660 C C . VAL A 1 709 ? -62.422 3.303 -18.811 1.00 25.32 ? 709 VAL A C 1 ATOM 5661 O O . VAL A 1 709 ? -62.557 4.319 -19.522 1.00 23.49 ? 709 VAL A O 1 ATOM 5662 C CB . VAL A 1 709 ? -60.109 2.271 -18.377 1.00 25.79 ? 709 VAL A CB 1 ATOM 5663 C CG1 . VAL A 1 709 ? -59.175 1.194 -18.848 1.00 26.43 ? 709 VAL A CG1 1 ATOM 5664 C CG2 . VAL A 1 709 ? -59.439 3.665 -18.452 1.00 23.67 ? 709 VAL A CG2 1 ATOM 5665 N N . ARG A 1 710 ? -63.153 3.069 -17.723 1.00 26.06 ? 710 ARG A N 1 ATOM 5666 C CA . ARG A 1 710 ? -64.076 4.093 -17.228 1.00 29.86 ? 710 ARG A CA 1 ATOM 5667 C C . ARG A 1 710 ? -63.276 5.199 -16.506 1.00 29.35 ? 710 ARG A C 1 ATOM 5668 O O . ARG A 1 710 ? -63.682 6.355 -16.484 1.00 31.80 ? 710 ARG A O 1 ATOM 5669 C CB . ARG A 1 710 ? -65.167 3.489 -16.327 1.00 29.66 ? 710 ARG A CB 1 ATOM 5670 C CG . ARG A 1 710 ? -64.625 2.631 -15.159 1.00 33.42 ? 710 ARG A CG 1 ATOM 5671 C CD . ARG A 1 710 ? -65.703 2.302 -14.081 1.00 35.16 ? 710 ARG A CD 1 ATOM 5672 N NE . ARG A 1 710 ? -65.068 1.997 -12.790 1.00 46.61 ? 710 ARG A NE 1 ATOM 5673 C CZ . ARG A 1 710 ? -64.726 2.908 -11.872 1.00 51.07 ? 710 ARG A CZ 1 ATOM 5674 N NH1 . ARG A 1 710 ? -64.953 4.209 -12.084 1.00 53.82 ? 710 ARG A NH1 1 ATOM 5675 N NH2 . ARG A 1 710 ? -64.151 2.527 -10.728 1.00 52.40 ? 710 ARG A NH2 1 ATOM 5676 N N . TRP A 1 711 ? -62.111 4.871 -15.981 1.00 28.51 ? 711 TRP A N 1 ATOM 5677 C CA . TRP A 1 711 ? -61.364 5.845 -15.180 1.00 27.43 ? 711 TRP A CA 1 ATOM 5678 C C . TRP A 1 711 ? -60.791 7.014 -15.965 1.00 26.00 ? 711 TRP A C 1 ATOM 5679 O O . TRP A 1 711 ? -60.316 6.845 -17.082 1.00 25.19 ? 711 TRP A O 1 ATOM 5680 C CB . TRP A 1 711 ? -60.222 5.148 -14.483 1.00 28.29 ? 711 TRP A CB 1 ATOM 5681 C CG . TRP A 1 711 ? -60.609 3.858 -13.818 1.00 31.00 ? 711 TRP A CG 1 ATOM 5682 C CD1 . TRP A 1 711 ? -61.649 3.646 -12.938 1.00 32.12 ? 711 TRP A CD1 1 ATOM 5683 C CD2 . TRP A 1 711 ? -59.944 2.605 -13.965 1.00 32.55 ? 711 TRP A CD2 1 ATOM 5684 N NE1 . TRP A 1 711 ? -61.661 2.335 -12.542 1.00 32.83 ? 711 TRP A NE1 1 ATOM 5685 C CE2 . TRP A 1 711 ? -60.627 1.673 -13.154 1.00 33.19 ? 711 TRP A CE2 1 ATOM 5686 C CE3 . TRP A 1 711 ? -58.836 2.173 -14.711 1.00 31.51 ? 711 TRP A CE3 1 ATOM 5687 C CZ2 . TRP A 1 711 ? -60.230 0.337 -13.057 1.00 32.40 ? 711 TRP A CZ2 1 ATOM 5688 C CZ3 . TRP A 1 711 ? -58.450 0.837 -14.616 1.00 31.81 ? 711 TRP A CZ3 1 ATOM 5689 C CH2 . TRP A 1 711 ? -59.139 -0.058 -13.793 1.00 31.39 ? 711 TRP A CH2 1 ATOM 5690 N N . ARG A 1 712 ? -60.774 8.195 -15.344 1.00 24.99 ? 712 ARG A N 1 ATOM 5691 C CA . ARG A 1 712 ? -60.082 9.352 -15.920 1.00 23.84 ? 712 ARG A CA 1 ATOM 5692 C C . ARG A 1 712 ? -59.728 10.347 -14.827 1.00 22.99 ? 712 ARG A C 1 ATOM 5693 O O . ARG A 1 712 ? -60.588 10.754 -14.025 1.00 21.51 ? 712 ARG A O 1 ATOM 5694 C CB . ARG A 1 712 ? -60.953 10.050 -16.965 1.00 24.59 ? 712 ARG A CB 1 ATOM 5695 C CG . ARG A 1 712 ? -60.235 11.197 -17.657 1.00 23.82 ? 712 ARG A CG 1 ATOM 5696 C CD . ARG A 1 712 ? -60.983 11.706 -18.855 1.00 28.67 ? 712 ARG A CD 1 ATOM 5697 N NE . ARG A 1 712 ? -60.159 12.704 -19.538 1.00 28.83 ? 712 ARG A NE 1 ATOM 5698 C CZ . ARG A 1 712 ? -60.267 13.038 -20.810 1.00 29.90 ? 712 ARG A CZ 1 ATOM 5699 N NH1 . ARG A 1 712 ? -61.155 12.431 -21.589 1.00 28.77 ? 712 ARG A NH1 1 ATOM 5700 N NH2 . ARG A 1 712 ? -59.456 13.964 -21.306 1.00 30.89 ? 712 ARG A NH2 1 ATOM 5701 N N . LYS A 1 713 ? -58.459 10.748 -14.778 1.00 21.26 ? 713 LYS A N 1 ATOM 5702 C CA . LYS A 1 713 ? -58.039 11.744 -13.793 1.00 21.24 ? 713 LYS A CA 1 ATOM 5703 C C . LYS A 1 713 ? -58.389 11.330 -12.355 1.00 21.63 ? 713 LYS A C 1 ATOM 5704 O O . LYS A 1 713 ? -59.043 12.067 -11.597 1.00 20.95 ? 713 LYS A O 1 ATOM 5705 C CB . LYS A 1 713 ? -58.588 13.151 -14.130 1.00 20.92 ? 713 LYS A CB 1 ATOM 5706 C CG . LYS A 1 713 ? -57.751 14.271 -13.465 1.00 22.07 ? 713 LYS A CG 1 ATOM 5707 C CD . LYS A 1 713 ? -58.223 15.704 -13.861 1.00 20.27 ? 713 LYS A CD 1 ATOM 5708 C CE . LYS A 1 713 ? -57.230 16.774 -13.306 1.00 22.21 ? 713 LYS A CE 1 ATOM 5709 N NZ . LYS A 1 713 ? -57.575 18.185 -13.655 1.00 24.49 ? 713 LYS A NZ 1 ATOM 5710 N N . GLN A 1 714 ? -57.944 10.152 -11.957 1.00 21.33 ? 714 GLN A N 1 ATOM 5711 C CA . GLN A 1 714 ? -58.346 9.658 -10.651 1.00 22.74 ? 714 GLN A CA 1 ATOM 5712 C C . GLN A 1 714 ? -57.480 8.521 -10.197 1.00 23.17 ? 714 GLN A C 1 ATOM 5713 O O . GLN A 1 714 ? -56.860 7.813 -11.013 1.00 22.70 ? 714 GLN A O 1 ATOM 5714 C CB . GLN A 1 714 ? -59.813 9.204 -10.660 1.00 22.74 ? 714 GLN A CB 1 ATOM 5715 C CG . GLN A 1 714 ? -60.078 7.982 -11.526 1.00 24.32 ? 714 GLN A CG 1 ATOM 5716 C CD . GLN A 1 714 ? -61.556 7.689 -11.607 1.00 28.76 ? 714 GLN A CD 1 ATOM 5717 O OE1 . GLN A 1 714 ? -62.142 7.220 -10.627 1.00 34.46 ? 714 GLN A OE1 1 ATOM 5718 N NE2 . GLN A 1 714 ? -62.182 7.994 -12.747 1.00 24.96 ? 714 GLN A NE2 1 ATOM 5719 N N . LYS A 1 715 ? -57.468 8.334 -8.891 1.00 23.89 ? 715 LYS A N 1 ATOM 5720 C CA . LYS A 1 715 ? -56.770 7.224 -8.298 1.00 27.33 ? 715 LYS A CA 1 ATOM 5721 C C . LYS A 1 715 ? -57.711 6.039 -8.364 1.00 27.07 ? 715 LYS A C 1 ATOM 5722 O O . LYS A 1 715 ? -58.904 6.199 -8.110 1.00 28.42 ? 715 LYS A O 1 ATOM 5723 C CB . LYS A 1 715 ? -56.404 7.522 -6.859 1.00 26.45 ? 715 LYS A CB 1 ATOM 5724 C CG . LYS A 1 715 ? -55.235 6.667 -6.385 1.00 30.53 ? 715 LYS A CG 1 ATOM 5725 C CD . LYS A 1 715 ? -54.783 6.980 -4.935 1.00 31.83 ? 715 LYS A CD 1 ATOM 5726 C CE . LYS A 1 715 ? -53.348 6.455 -4.692 1.00 37.36 ? 715 LYS A CE 1 ATOM 5727 N NZ . LYS A 1 715 ? -52.369 6.804 -5.799 1.00 40.68 ? 715 LYS A NZ 1 ATOM 5728 N N . VAL A 1 716 ? -57.192 4.872 -8.739 1.00 27.29 ? 716 VAL A N 1 ATOM 5729 C CA . VAL A 1 716 ? -57.985 3.626 -8.800 1.00 28.18 ? 716 VAL A CA 1 ATOM 5730 C C . VAL A 1 716 ? -57.206 2.458 -8.177 1.00 28.76 ? 716 VAL A C 1 ATOM 5731 O O . VAL A 1 716 ? -55.986 2.511 -8.069 1.00 29.12 ? 716 VAL A O 1 ATOM 5732 C CB . VAL A 1 716 ? -58.342 3.242 -10.248 1.00 27.80 ? 716 VAL A CB 1 ATOM 5733 C CG1 . VAL A 1 716 ? -59.111 4.372 -10.936 1.00 28.39 ? 716 VAL A CG1 1 ATOM 5734 C CG2 . VAL A 1 716 ? -57.080 2.919 -11.053 1.00 28.19 ? 716 VAL A CG2 1 ATOM 5735 N N . GLU A 1 717 ? -57.905 1.404 -7.782 1.00 29.57 ? 717 GLU A N 1 ATOM 5736 C CA . GLU A 1 717 ? -57.217 0.151 -7.480 1.00 30.74 ? 717 GLU A CA 1 ATOM 5737 C C . GLU A 1 717 ? -57.386 -0.718 -8.725 1.00 29.78 ? 717 GLU A C 1 ATOM 5738 O O . GLU A 1 717 ? -58.505 -1.114 -9.098 1.00 29.66 ? 717 GLU A O 1 ATOM 5739 C CB . GLU A 1 717 ? -57.750 -0.527 -6.208 1.00 31.64 ? 717 GLU A CB 1 ATOM 5740 C CG . GLU A 1 717 ? -59.110 -1.168 -6.393 1.00 38.66 ? 717 GLU A CG 1 ATOM 5741 C CD . GLU A 1 717 ? -59.328 -2.369 -5.470 1.00 46.84 ? 717 GLU A CD 1 ATOM 5742 O OE1 . GLU A 1 717 ? -58.714 -2.394 -4.361 1.00 49.53 ? 717 GLU A OE1 1 ATOM 5743 O OE2 . GLU A 1 717 ? -60.108 -3.275 -5.866 1.00 49.29 ? 717 GLU A OE2 1 ATOM 5744 N N . MET A 1 718 ? -56.286 -0.938 -9.427 1.00 28.07 ? 718 MET A N 1 ATOM 5745 C CA . MET A 1 718 ? -56.346 -1.668 -10.673 1.00 28.00 ? 718 MET A CA 1 ATOM 5746 C C . MET A 1 718 ? -56.186 -3.142 -10.339 1.00 27.17 ? 718 MET A C 1 ATOM 5747 O O . MET A 1 718 ? -55.294 -3.490 -9.564 1.00 26.61 ? 718 MET A O 1 ATOM 5748 C CB . MET A 1 718 ? -55.198 -1.197 -11.556 1.00 28.12 ? 718 MET A CB 1 ATOM 5749 C CG . MET A 1 718 ? -55.452 -1.306 -13.014 1.00 30.67 ? 718 MET A CG 1 ATOM 5750 S SD . MET A 1 718 ? -54.028 -0.587 -13.857 1.00 29.09 ? 718 MET A SD 1 ATOM 5751 C CE . MET A 1 718 ? -54.393 1.162 -13.925 1.00 23.58 ? 718 MET A CE 1 ATOM 5752 N N . GLU A 1 719 ? -57.032 -4.005 -10.888 1.00 26.61 ? 719 GLU A N 1 ATOM 5753 C CA . GLU A 1 719 ? -56.962 -5.435 -10.528 1.00 27.09 ? 719 GLU A CA 1 ATOM 5754 C C . GLU A 1 719 ? -55.890 -6.073 -11.398 1.00 26.05 ? 719 GLU A C 1 ATOM 5755 O O . GLU A 1 719 ? -56.011 -6.102 -12.619 1.00 26.04 ? 719 GLU A O 1 ATOM 5756 C CB . GLU A 1 719 ? -58.282 -6.167 -10.771 1.00 28.37 ? 719 GLU A CB 1 ATOM 5757 C CG . GLU A 1 719 ? -59.509 -5.492 -10.175 1.00 35.48 ? 719 GLU A CG 1 ATOM 5758 C CD . GLU A 1 719 ? -59.736 -5.793 -8.695 1.00 44.04 ? 719 GLU A CD 1 ATOM 5759 O OE1 . GLU A 1 719 ? -58.758 -6.079 -7.973 1.00 47.89 ? 719 GLU A OE1 1 ATOM 5760 O OE2 . GLU A 1 719 ? -60.915 -5.721 -8.246 1.00 48.30 ? 719 GLU A OE2 1 ATOM 5761 N N . LEU A 1 720 ? -54.840 -6.567 -10.774 1.00 24.28 ? 720 LEU A N 1 ATOM 5762 C CA . LEU A 1 720 ? -53.734 -7.116 -11.545 1.00 24.05 ? 720 LEU A CA 1 ATOM 5763 C C . LEU A 1 720 ? -53.275 -8.438 -10.929 1.00 23.04 ? 720 LEU A C 1 ATOM 5764 O O . LEU A 1 720 ? -52.359 -8.466 -10.117 1.00 21.86 ? 720 LEU A O 1 ATOM 5765 C CB . LEU A 1 720 ? -52.602 -6.110 -11.664 1.00 22.72 ? 720 LEU A CB 1 ATOM 5766 C CG . LEU A 1 720 ? -52.858 -4.772 -12.350 1.00 25.21 ? 720 LEU A CG 1 ATOM 5767 C CD1 . LEU A 1 720 ? -51.625 -3.910 -12.120 1.00 22.72 ? 720 LEU A CD1 1 ATOM 5768 C CD2 . LEU A 1 720 ? -53.212 -4.943 -13.834 1.00 24.74 ? 720 LEU A CD2 1 ATOM 5769 N N . PRO A 1 721 ? -53.918 -9.544 -11.340 1.00 23.58 ? 721 PRO A N 1 ATOM 5770 C CA . PRO A 1 721 ? -53.583 -10.892 -10.822 1.00 24.28 ? 721 PRO A CA 1 ATOM 5771 C C . PRO A 1 721 ? -52.143 -11.276 -11.192 1.00 24.09 ? 721 PRO A C 1 ATOM 5772 O O . PRO A 1 721 ? -51.483 -10.521 -11.912 1.00 24.49 ? 721 PRO A O 1 ATOM 5773 C CB . PRO A 1 721 ? -54.610 -11.811 -11.479 1.00 24.76 ? 721 PRO A CB 1 ATOM 5774 C CG . PRO A 1 721 ? -55.256 -11.013 -12.553 1.00 25.04 ? 721 PRO A CG 1 ATOM 5775 C CD . PRO A 1 721 ? -55.023 -9.560 -12.309 1.00 23.85 ? 721 PRO A CD 1 ATOM 5776 N N . GLY A 1 722 ? -51.643 -12.394 -10.679 1.00 23.27 ? 722 GLY A N 1 ATOM 5777 C CA . GLY A 1 722 ? -50.204 -12.727 -10.828 1.00 22.89 ? 722 GLY A CA 1 ATOM 5778 C C . GLY A 1 722 ? -49.636 -12.777 -12.242 1.00 22.38 ? 722 GLY A C 1 ATOM 5779 O O . GLY A 1 722 ? -48.405 -12.732 -12.421 1.00 22.64 ? 722 GLY A O 1 ATOM 5780 N N . ASP A 1 723 ? -50.516 -12.899 -13.239 1.00 22.55 ? 723 ASP A N 1 ATOM 5781 C CA . ASP A 1 723 ? -50.129 -12.944 -14.646 1.00 23.38 ? 723 ASP A CA 1 ATOM 5782 C C . ASP A 1 723 ? -50.246 -11.591 -15.394 1.00 22.52 ? 723 ASP A C 1 ATOM 5783 O O . ASP A 1 723 ? -50.068 -11.552 -16.610 1.00 22.75 ? 723 ASP A O 1 ATOM 5784 C CB . ASP A 1 723 ? -50.883 -14.065 -15.406 1.00 24.42 ? 723 ASP A CB 1 ATOM 5785 C CG . ASP A 1 723 ? -52.418 -13.848 -15.473 1.00 28.12 ? 723 ASP A CG 1 ATOM 5786 O OD1 . ASP A 1 723 ? -53.007 -13.131 -14.628 1.00 26.29 ? 723 ASP A OD1 1 ATOM 5787 O OD2 . ASP A 1 723 ? -53.052 -14.436 -16.389 1.00 34.00 ? 723 ASP A OD2 1 ATOM 5788 N N . LYS A 1 724 ? -50.547 -10.496 -14.675 1.00 21.64 ? 724 LYS A N 1 ATOM 5789 C CA . LYS A 1 724 ? -50.814 -9.198 -15.323 1.00 20.18 ? 724 LYS A CA 1 ATOM 5790 C C . LYS A 1 724 ? -49.990 -8.047 -14.807 1.00 19.01 ? 724 LYS A C 1 ATOM 5791 O O . LYS A 1 724 ? -49.672 -7.989 -13.626 1.00 20.23 ? 724 LYS A O 1 ATOM 5792 C CB . LYS A 1 724 ? -52.295 -8.784 -15.177 1.00 21.56 ? 724 LYS A CB 1 ATOM 5793 C CG . LYS A 1 724 ? -53.296 -9.758 -15.792 1.00 22.61 ? 724 LYS A CG 1 ATOM 5794 C CD . LYS A 1 724 ? -53.011 -10.069 -17.241 1.00 26.70 ? 724 LYS A CD 1 ATOM 5795 C CE . LYS A 1 724 ? -54.085 -11.023 -17.850 1.00 27.50 ? 724 LYS A CE 1 ATOM 5796 N NZ . LYS A 1 724 ? -53.939 -11.084 -19.341 1.00 33.67 ? 724 LYS A NZ 1 ATOM 5797 N N . ILE A 1 725 ? -49.701 -7.120 -15.720 1.00 17.05 ? 725 ILE A N 1 ATOM 5798 C CA . ILE A 1 725 ? -49.265 -5.795 -15.379 1.00 17.50 ? 725 ILE A CA 1 ATOM 5799 C C . ILE A 1 725 ? -50.133 -4.845 -16.144 1.00 17.01 ? 725 ILE A C 1 ATOM 5800 O O . ILE A 1 725 ? -50.591 -5.172 -17.213 1.00 18.17 ? 725 ILE A O 1 ATOM 5801 C CB . ILE A 1 725 ? -47.769 -5.587 -15.789 1.00 16.13 ? 725 ILE A CB 1 ATOM 5802 C CG1 . ILE A 1 725 ? -47.358 -4.139 -15.689 1.00 16.20 ? 725 ILE A CG1 1 ATOM 5803 C CG2 . ILE A 1 725 ? -47.531 -6.046 -17.194 1.00 18.37 ? 725 ILE A CG2 1 ATOM 5804 C CD1 . ILE A 1 725 ? -45.790 -3.998 -15.552 1.00 16.39 ? 725 ILE A CD1 1 ATOM 5805 N N . GLY A 1 726 ? -50.406 -3.681 -15.573 1.00 17.68 ? 726 GLY A N 1 ATOM 5806 C CA . GLY A 1 726 ? -51.239 -2.695 -16.258 1.00 16.81 ? 726 GLY A CA 1 ATOM 5807 C C . GLY A 1 726 ? -50.533 -2.068 -17.450 1.00 16.37 ? 726 GLY A C 1 ATOM 5808 O O . GLY A 1 726 ? -49.400 -1.580 -17.334 1.00 15.13 ? 726 GLY A O 1 ATOM 5809 N N . LEU A 1 727 ? -51.201 -2.081 -18.600 1.00 15.90 ? 727 LEU A N 1 ATOM 5810 C CA . LEU A 1 727 ? -50.690 -1.418 -19.796 1.00 16.44 ? 727 LEU A CA 1 ATOM 5811 C C . LEU A 1 727 ? -51.874 -0.763 -20.424 1.00 16.73 ? 727 LEU A C 1 ATOM 5812 O O . LEU A 1 727 ? -52.838 -1.483 -20.778 1.00 17.70 ? 727 LEU A O 1 ATOM 5813 C CB . LEU A 1 727 ? -50.156 -2.421 -20.818 1.00 15.63 ? 727 LEU A CB 1 ATOM 5814 C CG . LEU A 1 727 ? -48.956 -3.249 -20.418 1.00 18.02 ? 727 LEU A CG 1 ATOM 5815 C CD1 . LEU A 1 727 ? -48.734 -4.319 -21.491 1.00 18.36 ? 727 LEU A CD1 1 ATOM 5816 C CD2 . LEU A 1 727 ? -47.804 -2.274 -20.325 1.00 14.62 ? 727 LEU A CD2 1 ATOM 5817 N N . HIS A 1 728 ? -51.816 0.567 -20.597 1.00 16.12 ? 728 HIS A N 1 ATOM 5818 C CA . HIS A 1 728 ? -52.928 1.299 -21.216 1.00 16.33 ? 728 HIS A CA 1 ATOM 5819 C C . HIS A 1 728 ? -52.441 2.225 -22.273 1.00 16.59 ? 728 HIS A C 1 ATOM 5820 O O . HIS A 1 728 ? -51.396 2.855 -22.127 1.00 15.93 ? 728 HIS A O 1 ATOM 5821 C CB . HIS A 1 728 ? -53.670 2.078 -20.149 1.00 16.12 ? 728 HIS A CB 1 ATOM 5822 C CG . HIS A 1 728 ? -54.346 1.183 -19.179 1.00 17.52 ? 728 HIS A CG 1 ATOM 5823 N ND1 . HIS A 1 728 ? -53.689 0.625 -18.103 1.00 14.04 ? 728 HIS A ND1 1 ATOM 5824 C CD2 . HIS A 1 728 ? -55.585 0.625 -19.200 1.00 12.16 ? 728 HIS A CD2 1 ATOM 5825 C CE1 . HIS A 1 728 ? -54.509 -0.187 -17.457 1.00 19.15 ? 728 HIS A CE1 1 ATOM 5826 N NE2 . HIS A 1 728 ? -55.668 -0.198 -18.101 1.00 16.01 ? 728 HIS A NE2 1 ATOM 5827 N N . LEU A 1 729 ? -53.207 2.296 -23.351 1.00 15.88 ? 729 LEU A N 1 ATOM 5828 C CA . LEU A 1 729 ? -52.913 3.190 -24.454 1.00 15.35 ? 729 LEU A CA 1 ATOM 5829 C C . LEU A 1 729 ? -53.687 4.491 -24.345 1.00 16.15 ? 729 LEU A C 1 ATOM 5830 O O . LEU A 1 729 ? -54.930 4.490 -24.138 1.00 16.46 ? 729 LEU A O 1 ATOM 5831 C CB . LEU A 1 729 ? -53.171 2.507 -25.805 1.00 13.99 ? 729 LEU A CB 1 ATOM 5832 C CG . LEU A 1 729 ? -52.218 1.306 -26.077 1.00 13.17 ? 729 LEU A CG 1 ATOM 5833 C CD1 . LEU A 1 729 ? -52.546 0.663 -27.388 1.00 15.64 ? 729 LEU A CD1 1 ATOM 5834 C CD2 . LEU A 1 729 ? -50.752 1.748 -26.166 1.00 15.89 ? 729 LEU A CD2 1 ATOM 5835 N N . ARG A 1 730 ? -52.972 5.589 -24.551 1.00 15.27 ? 730 ARG A N 1 ATOM 5836 C CA . ARG A 1 730 ? -53.536 6.935 -24.501 1.00 15.90 ? 730 ARG A CA 1 ATOM 5837 C C . ARG A 1 730 ? -54.320 7.326 -25.731 1.00 15.45 ? 730 ARG A C 1 ATOM 5838 O O . ARG A 1 730 ? -53.820 7.307 -26.840 1.00 14.67 ? 730 ARG A O 1 ATOM 5839 C CB . ARG A 1 730 ? -52.440 7.957 -24.235 1.00 16.16 ? 730 ARG A CB 1 ATOM 5840 C CG . ARG A 1 730 ? -52.958 9.393 -23.946 1.00 15.65 ? 730 ARG A CG 1 ATOM 5841 C CD . ARG A 1 730 ? -51.725 10.198 -23.587 1.00 15.24 ? 730 ARG A CD 1 ATOM 5842 N NE . ARG A 1 730 ? -51.993 11.625 -23.489 1.00 15.16 ? 730 ARG A NE 1 ATOM 5843 C CZ . ARG A 1 730 ? -51.042 12.543 -23.373 1.00 16.48 ? 730 ARG A CZ 1 ATOM 5844 N NH1 . ARG A 1 730 ? -49.750 12.184 -23.359 1.00 17.29 ? 730 ARG A NH1 1 ATOM 5845 N NH2 . ARG A 1 730 ? -51.378 13.825 -23.288 1.00 18.76 ? 730 ARG A NH2 1 ATOM 5846 N N . GLY A 1 731 ? -55.578 7.724 -25.529 1.00 15.59 ? 731 GLY A N 1 ATOM 5847 C CA . GLY A 1 731 ? -56.341 8.285 -26.622 1.00 15.87 ? 731 GLY A CA 1 ATOM 5848 C C . GLY A 1 731 ? -55.649 9.491 -27.235 1.00 15.75 ? 731 GLY A C 1 ATOM 5849 O O . GLY A 1 731 ? -55.188 10.399 -26.527 1.00 16.59 ? 731 GLY A O 1 ATOM 5850 N N . GLY A 1 732 ? -55.568 9.495 -28.564 1.00 14.64 ? 732 GLY A N 1 ATOM 5851 C CA . GLY A 1 732 ? -55.025 10.626 -29.320 1.00 14.92 ? 732 GLY A CA 1 ATOM 5852 C C . GLY A 1 732 ? -53.693 10.245 -29.937 1.00 14.30 ? 732 GLY A C 1 ATOM 5853 O O . GLY A 1 732 ? -53.081 11.051 -30.634 1.00 14.44 ? 732 GLY A O 1 ATOM 5854 N N . TYR A 1 733 ? -53.324 8.986 -29.724 1.00 14.17 ? 733 TYR A N 1 ATOM 5855 C CA . TYR A 1 733 ? -52.038 8.464 -30.196 1.00 14.91 ? 733 TYR A CA 1 ATOM 5856 C C . TYR A 1 733 ? -52.159 7.226 -31.100 1.00 14.53 ? 733 TYR A C 1 ATOM 5857 O O . TYR A 1 733 ? -53.065 6.393 -30.951 1.00 13.97 ? 733 TYR A O 1 ATOM 5858 C CB . TYR A 1 733 ? -51.111 8.264 -28.982 1.00 14.37 ? 733 TYR A CB 1 ATOM 5859 C CG . TYR A 1 733 ? -50.773 9.576 -28.354 1.00 16.99 ? 733 TYR A CG 1 ATOM 5860 C CD1 . TYR A 1 733 ? -49.635 10.306 -28.779 1.00 19.40 ? 733 TYR A CD1 1 ATOM 5861 C CD2 . TYR A 1 733 ? -51.599 10.136 -27.377 1.00 16.92 ? 733 TYR A CD2 1 ATOM 5862 C CE1 . TYR A 1 733 ? -49.350 11.543 -28.228 1.00 18.90 ? 733 TYR A CE1 1 ATOM 5863 C CE2 . TYR A 1 733 ? -51.331 11.400 -26.843 1.00 20.45 ? 733 TYR A CE2 1 ATOM 5864 C CZ . TYR A 1 733 ? -50.195 12.081 -27.274 1.00 21.21 ? 733 TYR A CZ 1 ATOM 5865 O OH . TYR A 1 733 ? -49.920 13.312 -26.736 1.00 21.58 ? 733 TYR A OH 1 ATOM 5866 N N . ILE A 1 734 ? -51.240 7.135 -32.067 1.00 14.46 ? 734 ILE A N 1 ATOM 5867 C CA . ILE A 1 734 ? -51.184 6.024 -33.023 1.00 13.73 ? 734 ILE A CA 1 ATOM 5868 C C . ILE A 1 734 ? -49.857 5.351 -32.832 1.00 16.54 ? 734 ILE A C 1 ATOM 5869 O O . ILE A 1 734 ? -48.821 6.058 -32.853 1.00 15.25 ? 734 ILE A O 1 ATOM 5870 C CB . ILE A 1 734 ? -51.339 6.520 -34.450 1.00 13.77 ? 734 ILE A CB 1 ATOM 5871 C CG1 . ILE A 1 734 ? -52.756 7.148 -34.577 1.00 14.69 ? 734 ILE A CG1 1 ATOM 5872 C CG2 . ILE A 1 734 ? -51.192 5.325 -35.496 1.00 13.21 ? 734 ILE A CG2 1 ATOM 5873 C CD1 . ILE A 1 734 ? -53.021 7.910 -35.834 1.00 13.01 ? 734 ILE A CD1 1 ATOM 5874 N N . PHE A 1 735 ? -49.915 4.042 -32.575 1.00 15.95 ? 735 PHE A N 1 ATOM 5875 C CA . PHE A 1 735 ? -48.740 3.242 -32.178 1.00 15.42 ? 735 PHE A CA 1 ATOM 5876 C C . PHE A 1 735 ? -48.409 2.281 -33.310 1.00 15.34 ? 735 PHE A C 1 ATOM 5877 O O . PHE A 1 735 ? -49.247 1.429 -33.685 1.00 15.88 ? 735 PHE A O 1 ATOM 5878 C CB . PHE A 1 735 ? -49.011 2.452 -30.899 1.00 14.78 ? 735 PHE A CB 1 ATOM 5879 C CG . PHE A 1 735 ? -49.468 3.305 -29.750 1.00 16.73 ? 735 PHE A CG 1 ATOM 5880 C CD1 . PHE A 1 735 ? -48.573 3.752 -28.791 1.00 16.25 ? 735 PHE A CD1 1 ATOM 5881 C CD2 . PHE A 1 735 ? -50.812 3.683 -29.646 1.00 12.41 ? 735 PHE A CD2 1 ATOM 5882 C CE1 . PHE A 1 735 ? -48.997 4.579 -27.736 1.00 14.64 ? 735 PHE A CE1 1 ATOM 5883 C CE2 . PHE A 1 735 ? -51.247 4.513 -28.602 1.00 10.52 ? 735 PHE A CE2 1 ATOM 5884 C CZ . PHE A 1 735 ? -50.376 4.944 -27.639 1.00 14.65 ? 735 PHE A CZ 1 ATOM 5885 N N . PRO A 1 736 ? -47.196 2.420 -33.868 1.00 15.23 ? 736 PRO A N 1 ATOM 5886 C CA . PRO A 1 736 ? -46.710 1.431 -34.828 1.00 15.09 ? 736 PRO A CA 1 ATOM 5887 C C . PRO A 1 736 ? -46.223 0.158 -34.130 1.00 16.03 ? 736 PRO A C 1 ATOM 5888 O O . PRO A 1 736 ? -45.497 0.203 -33.087 1.00 15.20 ? 736 PRO A O 1 ATOM 5889 C CB . PRO A 1 736 ? -45.556 2.155 -35.539 1.00 13.97 ? 736 PRO A CB 1 ATOM 5890 C CG . PRO A 1 736 ? -45.012 3.083 -34.480 1.00 15.45 ? 736 PRO A CG 1 ATOM 5891 C CD . PRO A 1 736 ? -46.213 3.500 -33.628 1.00 13.30 ? 736 PRO A CD 1 ATOM 5892 N N . THR A 1 737 ? -46.613 -0.981 -34.703 1.00 15.16 ? 737 THR A N 1 ATOM 5893 C CA . THR A 1 737 ? -46.297 -2.279 -34.129 1.00 15.66 ? 737 THR A CA 1 ATOM 5894 C C . THR A 1 737 ? -45.713 -3.174 -35.234 1.00 15.31 ? 737 THR A C 1 ATOM 5895 O O . THR A 1 737 ? -45.821 -2.876 -36.423 1.00 17.52 ? 737 THR A O 1 ATOM 5896 C CB . THR A 1 737 ? -47.556 -2.983 -33.561 1.00 17.61 ? 737 THR A CB 1 ATOM 5897 O OG1 . THR A 1 737 ? -48.426 -3.290 -34.646 1.00 18.27 ? 737 THR A OG1 1 ATOM 5898 C CG2 . THR A 1 737 ? -48.336 -2.092 -32.544 1.00 17.32 ? 737 THR A CG2 1 ATOM 5899 N N . GLN A 1 738 ? -45.071 -4.256 -34.839 1.00 15.42 ? 738 GLN A N 1 ATOM 5900 C CA . GLN A 1 738 ? -44.538 -5.246 -35.782 1.00 15.40 ? 738 GLN A CA 1 ATOM 5901 C C . GLN A 1 738 ? -44.641 -6.608 -35.116 1.00 15.60 ? 738 GLN A C 1 ATOM 5902 O O . GLN A 1 738 ? -44.239 -6.768 -33.956 1.00 16.15 ? 738 GLN A O 1 ATOM 5903 C CB . GLN A 1 738 ? -43.081 -4.909 -36.139 1.00 15.77 ? 738 GLN A CB 1 ATOM 5904 C CG . GLN A 1 738 ? -42.480 -5.851 -37.215 1.00 14.18 ? 738 GLN A CG 1 ATOM 5905 C CD . GLN A 1 738 ? -41.195 -5.267 -37.820 1.00 17.82 ? 738 GLN A CD 1 ATOM 5906 O OE1 . GLN A 1 738 ? -40.394 -4.733 -37.092 1.00 15.76 ? 738 GLN A OE1 1 ATOM 5907 N NE2 . GLN A 1 738 ? -41.016 -5.371 -39.131 1.00 17.98 ? 738 GLN A NE2 1 ATOM 5908 N N . GLN A 1 739 ? -45.187 -7.597 -35.837 1.00 15.22 ? 739 GLN A N 1 ATOM 5909 C CA . GLN A 1 739 ? -45.391 -8.913 -35.315 1.00 16.49 ? 739 GLN A CA 1 ATOM 5910 C C . GLN A 1 739 ? -44.070 -9.370 -34.694 1.00 17.20 ? 739 GLN A C 1 ATOM 5911 O O . GLN A 1 739 ? -43.018 -9.281 -35.352 1.00 18.16 ? 739 GLN A O 1 ATOM 5912 C CB . GLN A 1 739 ? -45.783 -9.884 -36.430 1.00 16.39 ? 739 GLN A CB 1 ATOM 5913 C CG . GLN A 1 739 ? -45.803 -11.323 -35.972 1.00 18.96 ? 739 GLN A CG 1 ATOM 5914 C CD . GLN A 1 739 ? -46.085 -12.279 -37.105 1.00 23.24 ? 739 GLN A CD 1 ATOM 5915 O OE1 . GLN A 1 739 ? -46.249 -11.842 -38.244 1.00 25.93 ? 739 GLN A OE1 1 ATOM 5916 N NE2 . GLN A 1 739 ? -46.193 -13.600 -36.791 1.00 20.78 ? 739 GLN A NE2 1 ATOM 5917 N N . PRO A 1 740 ? -44.138 -9.837 -33.445 1.00 17.37 ? 740 PRO A N 1 ATOM 5918 C CA . PRO A 1 740 ? -42.915 -10.182 -32.717 1.00 18.08 ? 740 PRO A CA 1 ATOM 5919 C C . PRO A 1 740 ? -42.314 -11.536 -33.178 1.00 20.19 ? 740 PRO A C 1 ATOM 5920 O O . PRO A 1 740 ? -42.972 -12.376 -33.793 1.00 18.94 ? 740 PRO A O 1 ATOM 5921 C CB . PRO A 1 740 ? -43.378 -10.252 -31.264 1.00 17.08 ? 740 PRO A CB 1 ATOM 5922 C CG . PRO A 1 740 ? -44.850 -10.656 -31.359 1.00 18.02 ? 740 PRO A CG 1 ATOM 5923 C CD . PRO A 1 740 ? -45.360 -9.992 -32.622 1.00 15.57 ? 740 PRO A CD 1 ATOM 5924 N N . ASN A 1 741 ? -41.036 -11.715 -32.903 1.00 21.26 ? 741 ASN A N 1 ATOM 5925 C CA A ASN A 1 741 ? -40.367 -12.985 -33.131 0.50 21.10 ? 741 ASN A CA 1 ATOM 5926 C CA B ASN A 1 741 ? -40.386 -13.000 -33.098 0.50 21.46 ? 741 ASN A CA 1 ATOM 5927 C C . ASN A 1 741 ? -39.404 -13.046 -31.944 1.00 21.28 ? 741 ASN A C 1 ATOM 5928 O O . ASN A 1 741 ? -39.301 -12.069 -31.171 1.00 21.38 ? 741 ASN A O 1 ATOM 5929 C CB A ASN A 1 741 ? -39.659 -13.002 -34.506 0.50 20.70 ? 741 ASN A CB 1 ATOM 5930 C CB B ASN A 1 741 ? -39.687 -13.057 -34.459 0.50 21.43 ? 741 ASN A CB 1 ATOM 5931 C CG A ASN A 1 741 ? -39.438 -14.439 -35.075 0.50 21.58 ? 741 ASN A CG 1 ATOM 5932 C CG B ASN A 1 741 ? -39.327 -14.499 -34.919 0.50 23.62 ? 741 ASN A CG 1 ATOM 5933 O OD1 A ASN A 1 741 ? -39.256 -15.385 -34.321 0.50 20.54 ? 741 ASN A OD1 1 ATOM 5934 O OD1 B ASN A 1 741 ? -38.716 -14.661 -35.971 0.50 27.12 ? 741 ASN A OD1 1 ATOM 5935 N ND2 A ASN A 1 741 ? -39.406 -14.566 -36.426 0.50 24.34 ? 741 ASN A ND2 1 ATOM 5936 N ND2 B ASN A 1 741 ? -39.678 -15.518 -34.144 0.50 25.63 ? 741 ASN A ND2 1 ATOM 5937 N N . THR A 1 742 ? -38.717 -14.154 -31.772 1.00 20.64 ? 742 THR A N 1 ATOM 5938 C CA . THR A 1 742 ? -37.830 -14.275 -30.608 1.00 19.62 ? 742 THR A CA 1 ATOM 5939 C C . THR A 1 742 ? -36.520 -13.492 -30.697 1.00 19.20 ? 742 THR A C 1 ATOM 5940 O O . THR A 1 742 ? -35.781 -13.457 -29.706 1.00 18.37 ? 742 THR A O 1 ATOM 5941 C CB . THR A 1 742 ? -37.500 -15.740 -30.342 1.00 20.21 ? 742 THR A CB 1 ATOM 5942 O OG1 . THR A 1 742 ? -36.855 -16.248 -31.504 1.00 19.83 ? 742 THR A OG1 1 ATOM 5943 C CG2 . THR A 1 742 ? -38.794 -16.539 -30.047 1.00 18.97 ? 742 THR A CG2 1 ATOM 5944 N N . THR A 1 743 ? -36.227 -12.898 -31.852 1.00 18.37 ? 743 THR A N 1 ATOM 5945 C CA . THR A 1 743 ? -35.108 -11.978 -31.998 1.00 18.84 ? 743 THR A CA 1 ATOM 5946 C C . THR A 1 743 ? -35.531 -10.817 -32.869 1.00 18.83 ? 743 THR A C 1 ATOM 5947 O O . THR A 1 743 ? -36.451 -10.944 -33.681 1.00 19.31 ? 743 THR A O 1 ATOM 5948 C CB . THR A 1 743 ? -33.856 -12.638 -32.662 1.00 17.50 ? 743 THR A CB 1 ATOM 5949 O OG1 . THR A 1 743 ? -34.125 -12.862 -34.043 1.00 18.31 ? 743 THR A OG1 1 ATOM 5950 C CG2 . THR A 1 743 ? -33.506 -13.980 -32.009 1.00 17.09 ? 743 THR A CG2 1 ATOM 5951 N N . THR A 1 744 ? -34.858 -9.682 -32.721 1.00 19.16 ? 744 THR A N 1 ATOM 5952 C CA . THR A 1 744 ? -35.165 -8.530 -33.572 1.00 20.75 ? 744 THR A CA 1 ATOM 5953 C C . THR A 1 744 ? -34.628 -8.711 -35.003 1.00 21.18 ? 744 THR A C 1 ATOM 5954 O O . THR A 1 744 ? -35.176 -8.147 -35.937 1.00 20.94 ? 744 THR A O 1 ATOM 5955 C CB . THR A 1 744 ? -34.637 -7.209 -33.002 1.00 20.94 ? 744 THR A CB 1 ATOM 5956 O OG1 . THR A 1 744 ? -33.202 -7.262 -32.926 1.00 21.03 ? 744 THR A OG1 1 ATOM 5957 C CG2 . THR A 1 744 ? -35.232 -6.906 -31.617 1.00 20.33 ? 744 THR A CG2 1 ATOM 5958 N N . LEU A 1 745 ? -33.556 -9.485 -35.187 1.00 21.18 ? 745 LEU A N 1 ATOM 5959 C CA . LEU A 1 745 ? -33.097 -9.790 -36.551 1.00 21.84 ? 745 LEU A CA 1 ATOM 5960 C C . LEU A 1 745 ? -34.292 -10.275 -37.370 1.00 21.60 ? 745 LEU A C 1 ATOM 5961 O O . LEU A 1 745 ? -34.547 -9.787 -38.468 1.00 21.62 ? 745 LEU A O 1 ATOM 5962 C CB . LEU A 1 745 ? -32.030 -10.901 -36.558 1.00 22.37 ? 745 LEU A CB 1 ATOM 5963 C CG . LEU A 1 745 ? -31.429 -11.204 -37.938 1.00 24.90 ? 745 LEU A CG 1 ATOM 5964 C CD1 . LEU A 1 745 ? -30.638 -10.030 -38.409 1.00 26.22 ? 745 LEU A CD1 1 ATOM 5965 C CD2 . LEU A 1 745 ? -30.503 -12.417 -37.933 1.00 24.53 ? 745 LEU A CD2 1 ATOM 5966 N N . ALA A 1 746 ? -35.019 -11.224 -36.798 1.00 20.27 ? 746 ALA A N 1 ATOM 5967 C CA . ALA A 1 746 ? -36.209 -11.785 -37.411 1.00 20.69 ? 746 ALA A CA 1 ATOM 5968 C C . ALA A 1 746 ? -37.455 -10.900 -37.317 1.00 20.45 ? 746 ALA A C 1 ATOM 5969 O O . ALA A 1 746 ? -38.167 -10.765 -38.315 1.00 20.83 ? 746 ALA A O 1 ATOM 5970 C CB . ALA A 1 746 ? -36.477 -13.152 -36.857 1.00 20.47 ? 746 ALA A CB 1 ATOM 5971 N N . SER A 1 747 ? -37.727 -10.264 -36.175 1.00 18.96 ? 747 SER A N 1 ATOM 5972 C CA . SER A 1 747 ? -39.018 -9.523 -36.036 1.00 18.85 ? 747 SER A CA 1 ATOM 5973 C C . SER A 1 747 ? -39.079 -8.341 -37.026 1.00 18.60 ? 747 SER A C 1 ATOM 5974 O O . SER A 1 747 ? -40.143 -8.008 -37.514 1.00 18.16 ? 747 SER A O 1 ATOM 5975 C CB . SER A 1 747 ? -39.215 -9.046 -34.590 1.00 18.51 ? 747 SER A CB 1 ATOM 5976 O OG . SER A 1 747 ? -38.250 -8.061 -34.282 1.00 18.46 ? 747 SER A OG 1 ATOM 5977 N N . ARG A 1 748 ? -37.919 -7.758 -37.349 1.00 16.88 ? 748 ARG A N 1 ATOM 5978 C CA . ARG A 1 748 ? -37.834 -6.625 -38.270 1.00 18.33 ? 748 ARG A CA 1 ATOM 5979 C C . ARG A 1 748 ? -38.265 -6.954 -39.703 1.00 17.72 ? 748 ARG A C 1 ATOM 5980 O O . ARG A 1 748 ? -38.449 -6.046 -40.498 1.00 18.87 ? 748 ARG A O 1 ATOM 5981 C CB . ARG A 1 748 ? -36.397 -6.064 -38.304 1.00 17.49 ? 748 ARG A CB 1 ATOM 5982 C CG . ARG A 1 748 ? -35.993 -5.292 -37.036 1.00 17.43 ? 748 ARG A CG 1 ATOM 5983 C CD . ARG A 1 748 ? -34.496 -4.849 -37.121 1.00 18.14 ? 748 ARG A CD 1 ATOM 5984 N NE . ARG A 1 748 ? -34.238 -4.144 -38.380 1.00 16.63 ? 748 ARG A NE 1 ATOM 5985 C CZ . ARG A 1 748 ? -34.434 -2.837 -38.562 1.00 18.22 ? 748 ARG A CZ 1 ATOM 5986 N NH1 . ARG A 1 748 ? -34.812 -2.048 -37.544 1.00 19.81 ? 748 ARG A NH1 1 ATOM 5987 N NH2 . ARG A 1 748 ? -34.207 -2.298 -39.750 1.00 17.63 ? 748 ARG A NH2 1 ATOM 5988 N N . LYS A 1 749 ? -38.365 -8.234 -40.038 1.00 18.87 ? 749 LYS A N 1 ATOM 5989 C CA . LYS A 1 749 ? -38.849 -8.690 -41.361 1.00 20.19 ? 749 LYS A CA 1 ATOM 5990 C C . LYS A 1 749 ? -40.368 -8.954 -41.348 1.00 19.62 ? 749 LYS A C 1 ATOM 5991 O O . LYS A 1 749 ? -40.966 -9.302 -42.368 1.00 19.74 ? 749 LYS A O 1 ATOM 5992 C CB . LYS A 1 749 ? -38.111 -9.978 -41.754 1.00 21.33 ? 749 LYS A CB 1 ATOM 5993 C CG . LYS A 1 749 ? -36.571 -9.820 -41.728 1.00 22.63 ? 749 LYS A CG 1 ATOM 5994 C CD . LYS A 1 749 ? -35.835 -11.154 -41.960 1.00 23.61 ? 749 LYS A CD 1 ATOM 5995 C CE . LYS A 1 749 ? -34.316 -11.000 -41.804 1.00 26.03 ? 749 LYS A CE 1 ATOM 5996 N NZ . LYS A 1 749 ? -33.505 -12.263 -42.107 1.00 26.88 ? 749 LYS A NZ 1 ATOM 5997 N N . ASN A 1 750 ? -41.000 -8.770 -40.206 1.00 18.82 ? 750 ASN A N 1 ATOM 5998 C CA . ASN A 1 750 ? -42.436 -9.134 -40.073 1.00 18.56 ? 750 ASN A CA 1 ATOM 5999 C C . ASN A 1 750 ? -43.421 -8.020 -40.494 1.00 17.92 ? 750 ASN A C 1 ATOM 6000 O O . ASN A 1 750 ? -43.050 -6.858 -40.585 1.00 17.49 ? 750 ASN A O 1 ATOM 6001 C CB . ASN A 1 750 ? -42.761 -9.587 -38.670 1.00 18.12 ? 750 ASN A CB 1 ATOM 6002 C CG . ASN A 1 750 ? -42.293 -10.995 -38.385 1.00 21.46 ? 750 ASN A CG 1 ATOM 6003 O OD1 . ASN A 1 750 ? -42.059 -11.786 -39.308 1.00 25.41 ? 750 ASN A OD1 1 ATOM 6004 N ND2 . ASN A 1 750 ? -42.159 -11.329 -37.103 1.00 19.25 ? 750 ASN A ND2 1 ATOM 6005 N N . PRO A 1 751 ? -44.683 -8.391 -40.761 1.00 18.50 ? 751 PRO A N 1 ATOM 6006 C CA . PRO A 1 751 ? -45.744 -7.430 -41.036 1.00 18.43 ? 751 PRO A CA 1 ATOM 6007 C C . PRO A 1 751 ? -45.891 -6.391 -39.913 1.00 17.27 ? 751 PRO A C 1 ATOM 6008 O O . PRO A 1 751 ? -45.760 -6.735 -38.750 1.00 18.04 ? 751 PRO A O 1 ATOM 6009 C CB . PRO A 1 751 ? -46.979 -8.316 -41.071 1.00 19.59 ? 751 PRO A CB 1 ATOM 6010 C CG . PRO A 1 751 ? -46.452 -9.614 -41.591 1.00 20.68 ? 751 PRO A CG 1 ATOM 6011 C CD . PRO A 1 751 ? -45.171 -9.779 -40.882 1.00 18.93 ? 751 PRO A CD 1 ATOM 6012 N N . LEU A 1 752 ? -46.174 -5.144 -40.280 1.00 16.81 ? 752 LEU A N 1 ATOM 6013 C CA . LEU A 1 752 ? -46.378 -4.088 -39.296 1.00 17.15 ? 752 LEU A CA 1 ATOM 6014 C C . LEU A 1 752 ? -47.867 -3.886 -39.059 1.00 18.37 ? 752 LEU A C 1 ATOM 6015 O O . LEU A 1 752 ? -48.660 -4.361 -39.812 1.00 17.35 ? 752 LEU A O 1 ATOM 6016 C CB . LEU A 1 752 ? -45.795 -2.777 -39.805 1.00 19.69 ? 752 LEU A CB 1 ATOM 6017 C CG . LEU A 1 752 ? -44.454 -2.896 -40.539 1.00 20.34 ? 752 LEU A CG 1 ATOM 6018 C CD1 . LEU A 1 752 ? -44.201 -1.644 -41.356 1.00 25.48 ? 752 LEU A CD1 1 ATOM 6019 C CD2 . LEU A 1 752 ? -43.396 -3.066 -39.518 1.00 22.65 ? 752 LEU A CD2 1 ATOM 6020 N N . GLY A 1 753 ? -48.199 -3.128 -38.025 1.00 18.09 ? 753 GLY A N 1 ATOM 6021 C CA . GLY A 1 753 ? -49.582 -2.812 -37.704 1.00 18.44 ? 753 GLY A CA 1 ATOM 6022 C C . GLY A 1 753 ? -49.614 -1.399 -37.174 1.00 18.45 ? 753 GLY A C 1 ATOM 6023 O O . GLY A 1 753 ? -48.575 -0.804 -36.889 1.00 16.27 ? 753 GLY A O 1 ATOM 6024 N N . LEU A 1 754 ? -50.812 -0.845 -37.078 1.00 17.90 ? 754 LEU A N 1 ATOM 6025 C CA . LEU A 1 754 ? -51.015 0.395 -36.409 1.00 18.11 ? 754 LEU A CA 1 ATOM 6026 C C . LEU A 1 754 ? -52.077 0.173 -35.343 1.00 17.89 ? 754 LEU A C 1 ATOM 6027 O O . LEU A 1 754 ? -53.087 -0.514 -35.605 1.00 18.97 ? 754 LEU A O 1 ATOM 6028 C CB . LEU A 1 754 ? -51.469 1.480 -37.399 1.00 17.02 ? 754 LEU A CB 1 ATOM 6029 C CG . LEU A 1 754 ? -50.509 2.008 -38.438 1.00 20.63 ? 754 LEU A CG 1 ATOM 6030 C CD1 . LEU A 1 754 ? -51.307 3.019 -39.289 1.00 21.73 ? 754 LEU A CD1 1 ATOM 6031 C CD2 . LEU A 1 754 ? -49.245 2.672 -37.727 1.00 15.61 ? 754 LEU A CD2 1 ATOM 6032 N N . ILE A 1 755 ? -51.863 0.737 -34.156 1.00 17.51 ? 755 ILE A N 1 ATOM 6033 C CA . ILE A 1 755 ? -52.958 0.851 -33.158 1.00 18.01 ? 755 ILE A CA 1 ATOM 6034 C C . ILE A 1 755 ? -53.342 2.336 -33.070 1.00 18.39 ? 755 ILE A C 1 ATOM 6035 O O . ILE A 1 755 ? -52.515 3.193 -32.732 1.00 17.55 ? 755 ILE A O 1 ATOM 6036 C CB . ILE A 1 755 ? -52.559 0.308 -31.747 1.00 18.35 ? 755 ILE A CB 1 ATOM 6037 C CG1 . ILE A 1 755 ? -51.994 -1.111 -31.817 1.00 18.89 ? 755 ILE A CG1 1 ATOM 6038 C CG2 . ILE A 1 755 ? -53.748 0.354 -30.768 1.00 15.98 ? 755 ILE A CG2 1 ATOM 6039 C CD1 . ILE A 1 755 ? -51.503 -1.638 -30.428 1.00 20.34 ? 755 ILE A CD1 1 ATOM 6040 N N . ILE A 1 756 ? -54.582 2.641 -33.422 1.00 18.31 ? 756 ILE A N 1 ATOM 6041 C CA . ILE A 1 756 ? -55.081 3.996 -33.386 1.00 17.89 ? 756 ILE A CA 1 ATOM 6042 C C . ILE A 1 756 ? -55.967 4.093 -32.137 1.00 19.94 ? 756 ILE A C 1 ATOM 6043 O O . ILE A 1 756 ? -57.057 3.527 -32.111 1.00 19.44 ? 756 ILE A O 1 ATOM 6044 C CB . ILE A 1 756 ? -55.905 4.255 -34.675 1.00 18.48 ? 756 ILE A CB 1 ATOM 6045 C CG1 . ILE A 1 756 ? -54.945 4.201 -35.883 1.00 16.50 ? 756 ILE A CG1 1 ATOM 6046 C CG2 . ILE A 1 756 ? -56.631 5.610 -34.599 1.00 16.18 ? 756 ILE A CG2 1 ATOM 6047 C CD1 . ILE A 1 756 ? -55.584 4.093 -37.243 1.00 15.95 ? 756 ILE A CD1 1 ATOM 6048 N N . ALA A 1 757 ? -55.517 4.805 -31.106 1.00 19.84 ? 757 ALA A N 1 ATOM 6049 C CA . ALA A 1 757 ? -56.307 4.975 -29.887 1.00 19.27 ? 757 ALA A CA 1 ATOM 6050 C C . ALA A 1 757 ? -57.000 6.328 -30.044 1.00 19.35 ? 757 ALA A C 1 ATOM 6051 O O . ALA A 1 757 ? -56.363 7.357 -29.967 1.00 18.94 ? 757 ALA A O 1 ATOM 6052 C CB . ALA A 1 757 ? -55.374 4.987 -28.662 1.00 19.36 ? 757 ALA A CB 1 ATOM 6053 N N . LEU A 1 758 ? -58.304 6.336 -30.313 1.00 19.33 ? 758 LEU A N 1 ATOM 6054 C CA . LEU A 1 758 ? -58.988 7.594 -30.577 1.00 18.99 ? 758 LEU A CA 1 ATOM 6055 C C . LEU A 1 758 ? -59.196 8.462 -29.308 1.00 18.56 ? 758 LEU A C 1 ATOM 6056 O O . LEU A 1 758 ? -59.509 7.937 -28.245 1.00 17.90 ? 758 LEU A O 1 ATOM 6057 C CB . LEU A 1 758 ? -60.327 7.304 -31.285 1.00 19.28 ? 758 LEU A CB 1 ATOM 6058 C CG . LEU A 1 758 ? -60.243 6.707 -32.680 1.00 19.50 ? 758 LEU A CG 1 ATOM 6059 C CD1 . LEU A 1 758 ? -61.655 6.543 -33.194 1.00 20.75 ? 758 LEU A CD1 1 ATOM 6060 C CD2 . LEU A 1 758 ? -59.424 7.588 -33.600 1.00 21.95 ? 758 LEU A CD2 1 ATOM 6061 N N . ASP A 1 759 ? -59.011 9.786 -29.419 1.00 19.87 ? 759 ASP A N 1 ATOM 6062 C CA . ASP A 1 759 ? -59.299 10.684 -28.289 1.00 21.13 ? 759 ASP A CA 1 ATOM 6063 C C . ASP A 1 759 ? -60.807 11.022 -28.309 1.00 22.79 ? 759 ASP A C 1 ATOM 6064 O O . ASP A 1 759 ? -61.523 10.441 -29.120 1.00 21.30 ? 759 ASP A O 1 ATOM 6065 C CB . ASP A 1 759 ? -58.432 11.945 -28.295 1.00 22.09 ? 759 ASP A CB 1 ATOM 6066 C CG . ASP A 1 759 ? -58.708 12.887 -29.461 1.00 24.42 ? 759 ASP A CG 1 ATOM 6067 O OD1 . ASP A 1 759 ? -59.784 12.822 -30.113 1.00 27.57 ? 759 ASP A OD1 1 ATOM 6068 O OD2 . ASP A 1 759 ? -57.804 13.723 -29.736 1.00 27.64 ? 759 ASP A OD2 1 ATOM 6069 N N . GLU A 1 760 ? -61.245 11.943 -27.446 1.00 24.37 ? 760 GLU A N 1 ATOM 6070 C CA . GLU A 1 760 ? -62.682 12.290 -27.297 1.00 27.56 ? 760 GLU A CA 1 ATOM 6071 C C . GLU A 1 760 ? -63.233 12.902 -28.573 1.00 27.93 ? 760 GLU A C 1 ATOM 6072 O O . GLU A 1 760 ? -64.450 12.872 -28.836 1.00 29.98 ? 760 GLU A O 1 ATOM 6073 C CB . GLU A 1 760 ? -62.871 13.296 -26.140 1.00 29.12 ? 760 GLU A CB 1 ATOM 6074 C CG . GLU A 1 760 ? -62.048 12.988 -24.873 1.00 34.70 ? 760 GLU A CG 1 ATOM 6075 C CD . GLU A 1 760 ? -60.707 13.747 -24.793 1.00 41.42 ? 760 GLU A CD 1 ATOM 6076 O OE1 . GLU A 1 760 ? -60.700 14.851 -24.181 1.00 45.77 ? 760 GLU A OE1 1 ATOM 6077 O OE2 . GLU A 1 760 ? -59.668 13.253 -25.311 1.00 40.00 ? 760 GLU A OE2 1 ATOM 6078 N N . ASN A 1 761 ? -62.352 13.494 -29.371 1.00 27.25 ? 761 ASN A N 1 ATOM 6079 C CA . ASN A 1 761 ? -62.751 14.027 -30.666 1.00 27.29 ? 761 ASN A CA 1 ATOM 6080 C C . ASN A 1 761 ? -62.586 13.057 -31.818 1.00 25.32 ? 761 ASN A C 1 ATOM 6081 O O . ASN A 1 761 ? -62.764 13.433 -32.964 1.00 25.43 ? 761 ASN A O 1 ATOM 6082 C CB . ASN A 1 761 ? -62.024 15.340 -30.916 1.00 28.04 ? 761 ASN A CB 1 ATOM 6083 C CG . ASN A 1 761 ? -62.256 16.327 -29.779 1.00 31.68 ? 761 ASN A CG 1 ATOM 6084 O OD1 . ASN A 1 761 ? -63.405 16.522 -29.329 1.00 34.90 ? 761 ASN A OD1 1 ATOM 6085 N ND2 . ASN A 1 761 ? -61.189 16.910 -29.278 1.00 30.22 ? 761 ASN A ND2 1 ATOM 6086 N N . LYS A 1 762 ? -62.293 11.799 -31.483 1.00 23.76 ? 762 LYS A N 1 ATOM 6087 C CA A LYS A 1 762 ? -62.087 10.710 -32.442 0.50 23.30 ? 762 LYS A CA 1 ATOM 6088 C CA B LYS A 1 762 ? -62.149 10.744 -32.501 0.50 23.27 ? 762 LYS A CA 1 ATOM 6089 C C . LYS A 1 762 ? -60.980 11.065 -33.434 1.00 22.43 ? 762 LYS A C 1 ATOM 6090 O O . LYS A 1 762 ? -61.061 10.851 -34.646 1.00 22.72 ? 762 LYS A O 1 ATOM 6091 C CB A LYS A 1 762 ? -63.422 10.211 -33.058 0.50 23.42 ? 762 LYS A CB 1 ATOM 6092 C CB B LYS A 1 762 ? -63.478 10.500 -33.291 0.50 23.17 ? 762 LYS A CB 1 ATOM 6093 C CG A LYS A 1 762 ? -64.432 9.725 -31.967 0.50 24.46 ? 762 LYS A CG 1 ATOM 6094 C CG B LYS A 1 762 ? -64.740 10.275 -32.410 0.50 24.43 ? 762 LYS A CG 1 ATOM 6095 C CD A LYS A 1 762 ? -63.773 8.800 -30.911 0.50 23.52 ? 762 LYS A CD 1 ATOM 6096 C CD B LYS A 1 762 ? -64.420 9.352 -31.217 0.50 23.98 ? 762 LYS A CD 1 ATOM 6097 C CE A LYS A 1 762 ? -64.630 8.573 -29.658 0.50 23.48 ? 762 LYS A CE 1 ATOM 6098 C CE B LYS A 1 762 ? -65.659 8.706 -30.608 0.50 24.28 ? 762 LYS A CE 1 ATOM 6099 N NZ A LYS A 1 762 ? -63.896 7.791 -28.619 0.50 24.89 ? 762 LYS A NZ 1 ATOM 6100 N NZ B LYS A 1 762 ? -66.128 9.391 -29.397 0.50 22.78 ? 762 LYS A NZ 1 ATOM 6101 N N . GLU A 1 763 ? -59.910 11.605 -32.855 1.00 21.36 ? 763 GLU A N 1 ATOM 6102 C CA . GLU A 1 763 ? -58.696 11.970 -33.595 1.00 21.27 ? 763 GLU A CA 1 ATOM 6103 C C . GLU A 1 763 ? -57.488 11.328 -32.940 1.00 18.42 ? 763 GLU A C 1 ATOM 6104 O O . GLU A 1 763 ? -57.548 10.913 -31.802 1.00 16.71 ? 763 GLU A O 1 ATOM 6105 C CB . GLU A 1 763 ? -58.500 13.488 -33.646 1.00 21.25 ? 763 GLU A CB 1 ATOM 6106 C CG . GLU A 1 763 ? -59.693 14.236 -34.275 1.00 25.98 ? 763 GLU A CG 1 ATOM 6107 C CD . GLU A 1 763 ? -59.433 15.702 -34.485 1.00 27.75 ? 763 GLU A CD 1 ATOM 6108 O OE1 . GLU A 1 763 ? -58.651 16.308 -33.698 1.00 36.10 ? 763 GLU A OE1 1 ATOM 6109 O OE2 . GLU A 1 763 ? -60.026 16.254 -35.443 1.00 35.61 ? 763 GLU A OE2 1 ATOM 6110 N N . ALA A 1 764 ? -56.373 11.256 -33.675 1.00 17.72 ? 764 ALA A N 1 ATOM 6111 C CA . ALA A 1 764 ? -55.180 10.632 -33.107 1.00 16.11 ? 764 ALA A CA 1 ATOM 6112 C C . ALA A 1 764 ? -54.032 10.937 -34.016 1.00 15.44 ? 764 ALA A C 1 ATOM 6113 O O . ALA A 1 764 ? -54.241 11.237 -35.177 1.00 15.78 ? 764 ALA A O 1 ATOM 6114 C CB . ALA A 1 764 ? -55.346 9.101 -33.006 1.00 16.21 ? 764 ALA A CB 1 ATOM 6115 N N . LYS A 1 765 ? -52.815 10.891 -33.490 1.00 14.75 ? 765 LYS A N 1 ATOM 6116 C CA . LYS A 1 765 ? -51.658 11.252 -34.339 1.00 16.07 ? 765 LYS A CA 1 ATOM 6117 C C . LYS A 1 765 ? -50.546 10.329 -33.918 1.00 14.67 ? 765 LYS A C 1 ATOM 6118 O O . LYS A 1 765 ? -50.542 9.877 -32.799 1.00 14.43 ? 765 LYS A O 1 ATOM 6119 C CB . LYS A 1 765 ? -51.203 12.706 -34.102 1.00 18.99 ? 765 LYS A CB 1 ATOM 6120 C CG . LYS A 1 765 ? -52.186 13.794 -34.578 1.00 25.86 ? 765 LYS A CG 1 ATOM 6121 C CD . LYS A 1 765 ? -51.417 14.994 -35.146 1.00 35.70 ? 765 LYS A CD 1 ATOM 6122 C CE . LYS A 1 765 ? -52.357 16.193 -35.376 1.00 39.96 ? 765 LYS A CE 1 ATOM 6123 N NZ . LYS A 1 765 ? -53.401 15.925 -36.425 1.00 42.78 ? 765 LYS A NZ 1 ATOM 6124 N N . GLY A 1 766 ? -49.614 10.014 -34.821 1.00 14.32 ? 766 GLY A N 1 ATOM 6125 C CA . GLY A 1 766 ? -48.483 9.221 -34.390 1.00 14.09 ? 766 GLY A CA 1 ATOM 6126 C C . GLY A 1 766 ? -47.391 9.375 -35.452 1.00 13.66 ? 766 GLY A C 1 ATOM 6127 O O . GLY A 1 766 ? -47.546 10.100 -36.446 1.00 13.27 ? 766 GLY A O 1 ATOM 6128 N N . GLU A 1 767 ? -46.289 8.686 -35.250 1.00 15.44 ? 767 GLU A N 1 ATOM 6129 C CA . GLU A 1 767 ? -45.239 8.673 -36.252 1.00 15.75 ? 767 GLU A CA 1 ATOM 6130 C C . GLU A 1 767 ? -44.458 7.365 -36.175 1.00 15.70 ? 767 GLU A C 1 ATOM 6131 O O . GLU A 1 767 ? -44.605 6.575 -35.215 1.00 13.74 ? 767 GLU A O 1 ATOM 6132 C CB . GLU A 1 767 ? -44.346 9.881 -36.054 1.00 17.52 ? 767 GLU A CB 1 ATOM 6133 C CG . GLU A 1 767 ? -43.519 9.815 -34.763 1.00 20.42 ? 767 GLU A CG 1 ATOM 6134 C CD . GLU A 1 767 ? -42.845 11.122 -34.391 1.00 26.69 ? 767 GLU A CD 1 ATOM 6135 O OE1 . GLU A 1 767 ? -42.856 12.089 -35.195 1.00 30.93 ? 767 GLU A OE1 1 ATOM 6136 O OE2 . GLU A 1 767 ? -42.255 11.171 -33.296 1.00 30.73 ? 767 GLU A OE2 1 ATOM 6137 N N . LEU A 1 768 ? -43.614 7.138 -37.183 1.00 16.34 ? 768 LEU A N 1 ATOM 6138 C CA . LEU A 1 768 ? -42.767 5.965 -37.232 1.00 15.90 ? 768 LEU A CA 1 ATOM 6139 C C . LEU A 1 768 ? -41.455 6.340 -37.899 1.00 15.95 ? 768 LEU A C 1 ATOM 6140 O O . LEU A 1 768 ? -41.439 6.861 -39.003 1.00 16.53 ? 768 LEU A O 1 ATOM 6141 C CB . LEU A 1 768 ? -43.426 4.799 -38.002 1.00 17.18 ? 768 LEU A CB 1 ATOM 6142 C CG . LEU A 1 768 ? -42.504 3.590 -38.281 1.00 15.66 ? 768 LEU A CG 1 ATOM 6143 C CD1 . LEU A 1 768 ? -41.989 2.940 -36.954 1.00 15.70 ? 768 LEU A CD1 1 ATOM 6144 C CD2 . LEU A 1 768 ? -43.264 2.549 -39.090 1.00 17.24 ? 768 LEU A CD2 1 ATOM 6145 N N . PHE A 1 769 ? -40.369 6.120 -37.184 1.00 14.72 ? 769 PHE A N 1 ATOM 6146 C CA . PHE A 1 769 ? -39.006 6.233 -37.750 1.00 14.33 ? 769 PHE A CA 1 ATOM 6147 C C . PHE A 1 769 ? -38.531 4.837 -38.169 1.00 14.59 ? 769 PHE A C 1 ATOM 6148 O O . PHE A 1 769 ? -38.747 3.850 -37.442 1.00 14.99 ? 769 PHE A O 1 ATOM 6149 C CB . PHE A 1 769 ? -38.103 6.778 -36.646 1.00 14.59 ? 769 PHE A CB 1 ATOM 6150 C CG . PHE A 1 769 ? -36.645 6.730 -36.987 1.00 12.79 ? 769 PHE A CG 1 ATOM 6151 C CD1 . PHE A 1 769 ? -36.078 7.683 -37.827 1.00 15.64 ? 769 PHE A CD1 1 ATOM 6152 C CD2 . PHE A 1 769 ? -35.851 5.734 -36.471 1.00 14.04 ? 769 PHE A CD2 1 ATOM 6153 C CE1 . PHE A 1 769 ? -34.679 7.644 -38.098 1.00 12.78 ? 769 PHE A CE1 1 ATOM 6154 C CE2 . PHE A 1 769 ? -34.459 5.710 -36.767 1.00 12.81 ? 769 PHE A CE2 1 ATOM 6155 C CZ . PHE A 1 769 ? -33.930 6.643 -37.595 1.00 14.94 ? 769 PHE A CZ 1 ATOM 6156 N N . TRP A 1 770 ? -37.889 4.717 -39.338 1.00 15.90 ? 770 TRP A N 1 ATOM 6157 C CA . TRP A 1 770 ? -37.408 3.406 -39.759 1.00 16.83 ? 770 TRP A CA 1 ATOM 6158 C C . TRP A 1 770 ? -36.115 3.589 -40.549 1.00 16.66 ? 770 TRP A C 1 ATOM 6159 O O . TRP A 1 770 ? -36.054 4.371 -41.500 1.00 16.71 ? 770 TRP A O 1 ATOM 6160 C CB . TRP A 1 770 ? -38.427 2.645 -40.603 1.00 17.91 ? 770 TRP A CB 1 ATOM 6161 C CG . TRP A 1 770 ? -38.141 1.167 -40.652 1.00 17.25 ? 770 TRP A CG 1 ATOM 6162 C CD1 . TRP A 1 770 ? -37.562 0.459 -41.691 1.00 17.85 ? 770 TRP A CD1 1 ATOM 6163 C CD2 . TRP A 1 770 ? -38.406 0.203 -39.621 1.00 21.86 ? 770 TRP A CD2 1 ATOM 6164 N NE1 . TRP A 1 770 ? -37.483 -0.869 -41.373 1.00 16.80 ? 770 TRP A NE1 1 ATOM 6165 C CE2 . TRP A 1 770 ? -37.973 -1.065 -40.110 1.00 18.47 ? 770 TRP A CE2 1 ATOM 6166 C CE3 . TRP A 1 770 ? -38.977 0.280 -38.329 1.00 22.82 ? 770 TRP A CE3 1 ATOM 6167 C CZ2 . TRP A 1 770 ? -38.104 -2.253 -39.360 1.00 20.07 ? 770 TRP A CZ2 1 ATOM 6168 C CZ3 . TRP A 1 770 ? -39.089 -0.906 -37.568 1.00 21.07 ? 770 TRP A CZ3 1 ATOM 6169 C CH2 . TRP A 1 770 ? -38.659 -2.159 -38.097 1.00 20.53 ? 770 TRP A CH2 1 ATOM 6170 N N . ASP A 1 771 ? -35.075 2.908 -40.102 1.00 17.49 ? 771 ASP A N 1 ATOM 6171 C CA . ASP A 1 771 ? -33.808 2.898 -40.837 1.00 16.68 ? 771 ASP A CA 1 ATOM 6172 C C . ASP A 1 771 ? -33.279 1.466 -40.774 1.00 17.31 ? 771 ASP A C 1 ATOM 6173 O O . ASP A 1 771 ? -34.004 0.557 -40.414 1.00 17.80 ? 771 ASP A O 1 ATOM 6174 C CB . ASP A 1 771 ? -32.837 3.960 -40.268 1.00 16.74 ? 771 ASP A CB 1 ATOM 6175 C CG . ASP A 1 771 ? -32.299 3.625 -38.858 1.00 15.54 ? 771 ASP A CG 1 ATOM 6176 O OD1 . ASP A 1 771 ? -32.706 2.635 -38.252 1.00 18.91 ? 771 ASP A OD1 1 ATOM 6177 O OD2 . ASP A 1 771 ? -31.424 4.381 -38.342 1.00 18.30 ? 771 ASP A OD2 1 ATOM 6178 N N . ASP A 1 772 ? -31.997 1.246 -41.066 1.00 17.56 ? 772 ASP A N 1 ATOM 6179 C CA . ASP A 1 772 ? -31.525 -0.109 -41.133 1.00 17.53 ? 772 ASP A CA 1 ATOM 6180 C C . ASP A 1 772 ? -31.229 -0.707 -39.749 1.00 17.07 ? 772 ASP A C 1 ATOM 6181 O O . ASP A 1 772 ? -30.886 -1.864 -39.657 1.00 16.93 ? 772 ASP A O 1 ATOM 6182 C CB . ASP A 1 772 ? -30.330 -0.244 -42.132 1.00 17.87 ? 772 ASP A CB 1 ATOM 6183 C CG . ASP A 1 772 ? -29.020 0.276 -41.556 1.00 21.81 ? 772 ASP A CG 1 ATOM 6184 O OD1 . ASP A 1 772 ? -29.023 0.702 -40.373 1.00 19.23 ? 772 ASP A OD1 1 ATOM 6185 O OD2 . ASP A 1 772 ? -27.979 0.304 -42.299 1.00 23.59 ? 772 ASP A OD2 1 ATOM 6186 N N . GLY A 1 773 ? -31.371 0.071 -38.672 1.00 17.46 ? 773 GLY A N 1 ATOM 6187 C CA . GLY A 1 773 ? -31.346 -0.503 -37.309 1.00 17.13 ? 773 GLY A CA 1 ATOM 6188 C C . GLY A 1 773 ? -29.915 -0.687 -36.787 1.00 17.84 ? 773 GLY A C 1 ATOM 6189 O O . GLY A 1 773 ? -29.707 -1.168 -35.669 1.00 17.16 ? 773 GLY A O 1 ATOM 6190 N N . GLU A 1 774 ? -28.912 -0.332 -37.582 1.00 18.49 ? 774 GLU A N 1 ATOM 6191 C CA . GLU A 1 774 ? -27.547 -0.602 -37.121 1.00 20.91 ? 774 GLU A CA 1 ATOM 6192 C C . GLU A 1 774 ? -26.419 0.282 -37.628 1.00 19.94 ? 774 GLU A C 1 ATOM 6193 O O . GLU A 1 774 ? -25.379 0.363 -36.967 1.00 19.39 ? 774 GLU A O 1 ATOM 6194 C CB . GLU A 1 774 ? -27.189 -2.078 -37.330 1.00 21.33 ? 774 GLU A CB 1 ATOM 6195 C CG . GLU A 1 774 ? -27.348 -2.618 -38.730 1.00 26.73 ? 774 GLU A CG 1 ATOM 6196 C CD . GLU A 1 774 ? -26.686 -3.998 -38.891 1.00 27.70 ? 774 GLU A CD 1 ATOM 6197 O OE1 . GLU A 1 774 ? -26.915 -4.899 -38.047 1.00 35.61 ? 774 GLU A OE1 1 ATOM 6198 O OE2 . GLU A 1 774 ? -25.925 -4.170 -39.875 1.00 35.83 ? 774 GLU A OE2 1 ATOM 6199 N N . THR A 1 775 ? -26.612 0.945 -38.762 1.00 20.28 ? 775 THR A N 1 ATOM 6200 C CA . THR A 1 775 ? -25.565 1.832 -39.310 1.00 21.57 ? 775 THR A CA 1 ATOM 6201 C C . THR A 1 775 ? -25.401 3.080 -38.473 1.00 22.26 ? 775 THR A C 1 ATOM 6202 O O . THR A 1 775 ? -26.403 3.679 -38.021 1.00 20.52 ? 775 THR A O 1 ATOM 6203 C CB . THR A 1 775 ? -25.847 2.159 -40.778 1.00 20.62 ? 775 THR A CB 1 ATOM 6204 O OG1 . THR A 1 775 ? -25.877 0.923 -41.491 1.00 22.12 ? 775 THR A OG1 1 ATOM 6205 C CG2 . THR A 1 775 ? -24.773 3.020 -41.365 1.00 22.79 ? 775 THR A CG2 1 ATOM 6206 N N . LYS A 1 776 ? -24.144 3.465 -38.226 1.00 23.22 ? 776 LYS A N 1 ATOM 6207 C CA . LYS A 1 776 ? -23.862 4.688 -37.464 1.00 26.22 ? 776 LYS A CA 1 ATOM 6208 C C . LYS A 1 776 ? -24.130 5.922 -38.348 1.00 26.96 ? 776 LYS A C 1 ATOM 6209 O O . LYS A 1 776 ? -23.883 5.894 -39.548 1.00 27.68 ? 776 LYS A O 1 ATOM 6210 C CB . LYS A 1 776 ? -22.414 4.667 -36.879 1.00 26.76 ? 776 LYS A CB 1 ATOM 6211 C CG . LYS A 1 776 ? -22.165 5.673 -35.728 1.00 29.83 ? 776 LYS A CG 1 ATOM 6212 C CD . LYS A 1 776 ? -20.785 5.506 -35.056 1.00 28.51 ? 776 LYS A CD 1 ATOM 6213 C CE . LYS A 1 776 ? -20.835 4.520 -33.858 1.00 32.05 ? 776 LYS A CE 1 ATOM 6214 N NZ . LYS A 1 776 ? -19.707 4.613 -32.823 1.00 31.70 ? 776 LYS A NZ 1 ATOM 6215 N N . ASP A 1 777 ? -24.707 6.974 -37.778 1.00 28.33 ? 777 ASP A N 1 ATOM 6216 C CA . ASP A 1 777 ? -24.934 8.241 -38.535 1.00 29.56 ? 777 ASP A CA 1 ATOM 6217 C C . ASP A 1 777 ? -26.074 8.240 -39.588 1.00 28.08 ? 777 ASP A C 1 ATOM 6218 O O . ASP A 1 777 ? -26.133 9.103 -40.454 1.00 28.75 ? 777 ASP A O 1 ATOM 6219 C CB . ASP A 1 777 ? -23.615 8.737 -39.150 1.00 31.23 ? 777 ASP A CB 1 ATOM 6220 C CG . ASP A 1 777 ? -22.627 9.230 -38.094 1.00 36.38 ? 777 ASP A CG 1 ATOM 6221 O OD1 . ASP A 1 777 ? -23.095 9.656 -37.002 1.00 41.22 ? 777 ASP A OD1 1 ATOM 6222 O OD2 . ASP A 1 777 ? -21.388 9.214 -38.362 1.00 41.55 ? 777 ASP A OD2 1 ATOM 6223 N N . THR A 1 778 ? -26.986 7.279 -39.521 1.00 26.57 ? 778 THR A N 1 ATOM 6224 C CA . THR A 1 778 ? -28.086 7.282 -40.470 1.00 25.38 ? 778 THR A CA 1 ATOM 6225 C C . THR A 1 778 ? -28.952 8.517 -40.278 1.00 24.99 ? 778 THR A C 1 ATOM 6226 O O . THR A 1 778 ? -29.625 8.939 -41.217 1.00 26.11 ? 778 THR A O 1 ATOM 6227 C CB . THR A 1 778 ? -28.999 6.049 -40.346 1.00 25.25 ? 778 THR A CB 1 ATOM 6228 O OG1 . THR A 1 778 ? -29.509 5.975 -39.016 1.00 26.38 ? 778 THR A OG1 1 ATOM 6229 C CG2 . THR A 1 778 ? -28.267 4.800 -40.651 1.00 23.42 ? 778 THR A CG2 1 ATOM 6230 N N . VAL A 1 779 ? -28.968 9.080 -39.070 1.00 23.93 ? 779 VAL A N 1 ATOM 6231 C CA . VAL A 1 779 ? -29.802 10.253 -38.819 1.00 23.60 ? 779 VAL A CA 1 ATOM 6232 C C . VAL A 1 779 ? -29.080 11.503 -39.340 1.00 24.60 ? 779 VAL A C 1 ATOM 6233 O O . VAL A 1 779 ? -29.636 12.270 -40.127 1.00 23.21 ? 779 VAL A O 1 ATOM 6234 C CB . VAL A 1 779 ? -30.250 10.373 -37.348 1.00 23.09 ? 779 VAL A CB 1 ATOM 6235 C CG1 . VAL A 1 779 ? -31.014 11.655 -37.129 1.00 22.48 ? 779 VAL A CG1 1 ATOM 6236 C CG2 . VAL A 1 779 ? -31.096 9.156 -36.928 1.00 23.04 ? 779 VAL A CG2 1 ATOM 6237 N N . ALA A 1 780 ? -27.812 11.657 -38.955 1.00 25.36 ? 780 ALA A N 1 ATOM 6238 C CA . ALA A 1 780 ? -26.987 12.747 -39.457 1.00 26.82 ? 780 ALA A CA 1 ATOM 6239 C C . ALA A 1 780 ? -26.842 12.723 -40.973 1.00 27.33 ? 780 ALA A C 1 ATOM 6240 O O . ALA A 1 780 ? -26.874 13.766 -41.608 1.00 27.94 ? 780 ALA A O 1 ATOM 6241 C CB . ALA A 1 780 ? -25.582 12.761 -38.768 1.00 26.48 ? 780 ALA A CB 1 ATOM 6242 N N . ASN A 1 781 ? -26.698 11.542 -41.561 1.00 28.23 ? 781 ASN A N 1 ATOM 6243 C CA . ASN A 1 781 ? -26.613 11.424 -43.003 1.00 28.89 ? 781 ASN A CA 1 ATOM 6244 C C . ASN A 1 781 ? -27.976 11.319 -43.687 1.00 28.44 ? 781 ASN A C 1 ATOM 6245 O O . ASN A 1 781 ? -28.058 11.148 -44.896 1.00 28.39 ? 781 ASN A O 1 ATOM 6246 C CB . ASN A 1 781 ? -25.735 10.254 -43.374 1.00 29.78 ? 781 ASN A CB 1 ATOM 6247 C CG . ASN A 1 781 ? -24.328 10.437 -42.862 1.00 33.34 ? 781 ASN A CG 1 ATOM 6248 O OD1 . ASN A 1 781 ? -23.690 9.491 -42.393 1.00 38.39 ? 781 ASN A OD1 1 ATOM 6249 N ND2 . ASN A 1 781 ? -23.850 11.681 -42.905 1.00 33.17 ? 781 ASN A ND2 1 ATOM 6250 N N . LYS A 1 782 ? -29.037 11.427 -42.907 1.00 27.84 ? 782 LYS A N 1 ATOM 6251 C CA . LYS A 1 782 ? -30.404 11.377 -43.464 1.00 26.69 ? 782 LYS A CA 1 ATOM 6252 C C . LYS A 1 782 ? -30.685 10.199 -44.397 1.00 25.38 ? 782 LYS A C 1 ATOM 6253 O O . LYS A 1 782 ? -31.164 10.396 -45.535 1.00 25.61 ? 782 LYS A O 1 ATOM 6254 C CB . LYS A 1 782 ? -30.710 12.660 -44.232 1.00 28.27 ? 782 LYS A CB 1 ATOM 6255 C CG . LYS A 1 782 ? -30.490 13.919 -43.483 1.00 31.17 ? 782 LYS A CG 1 ATOM 6256 C CD . LYS A 1 782 ? -31.768 14.406 -42.862 1.00 37.23 ? 782 LYS A CD 1 ATOM 6257 C CE . LYS A 1 782 ? -31.545 15.796 -42.290 1.00 40.89 ? 782 LYS A CE 1 ATOM 6258 N NZ . LYS A 1 782 ? -32.377 15.963 -41.057 1.00 43.70 ? 782 LYS A NZ 1 ATOM 6259 N N . VAL A 1 783 ? -30.433 8.988 -43.910 1.00 22.43 ? 783 VAL A N 1 ATOM 6260 C CA . VAL A 1 783 ? -30.785 7.753 -44.591 1.00 21.21 ? 783 VAL A CA 1 ATOM 6261 C C . VAL A 1 783 ? -31.841 7.106 -43.686 1.00 20.93 ? 783 VAL A C 1 ATOM 6262 O O . VAL A 1 783 ? -31.560 6.246 -42.860 1.00 21.38 ? 783 VAL A O 1 ATOM 6263 C CB . VAL A 1 783 ? -29.545 6.830 -44.853 1.00 21.62 ? 783 VAL A CB 1 ATOM 6264 C CG1 . VAL A 1 783 ? -29.922 5.636 -45.711 1.00 21.42 ? 783 VAL A CG1 1 ATOM 6265 C CG2 . VAL A 1 783 ? -28.444 7.614 -45.543 1.00 22.34 ? 783 VAL A CG2 1 ATOM 6266 N N . TYR A 1 784 ? -33.068 7.571 -43.814 1.00 19.50 ? 784 TYR A N 1 ATOM 6267 C CA . TYR A 1 784 ? -34.140 6.962 -43.013 1.00 18.55 ? 784 TYR A CA 1 ATOM 6268 C C . TYR A 1 784 ? -35.474 7.312 -43.565 1.00 18.69 ? 784 TYR A C 1 ATOM 6269 O O . TYR A 1 784 ? -35.567 8.192 -44.410 1.00 20.43 ? 784 TYR A O 1 ATOM 6270 C CB . TYR A 1 784 ? -34.082 7.394 -41.549 1.00 17.84 ? 784 TYR A CB 1 ATOM 6271 C CG . TYR A 1 784 ? -34.176 8.889 -41.223 1.00 18.84 ? 784 TYR A CG 1 ATOM 6272 C CD1 . TYR A 1 784 ? -35.391 9.476 -40.872 1.00 17.13 ? 784 TYR A CD1 1 ATOM 6273 C CD2 . TYR A 1 784 ? -33.025 9.683 -41.156 1.00 17.58 ? 784 TYR A CD2 1 ATOM 6274 C CE1 . TYR A 1 784 ? -35.469 10.833 -40.532 1.00 20.04 ? 784 TYR A CE1 1 ATOM 6275 C CE2 . TYR A 1 784 ? -33.086 11.011 -40.810 1.00 20.57 ? 784 TYR A CE2 1 ATOM 6276 C CZ . TYR A 1 784 ? -34.316 11.579 -40.497 1.00 20.20 ? 784 TYR A CZ 1 ATOM 6277 O OH . TYR A 1 784 ? -34.379 12.895 -40.148 1.00 19.65 ? 784 TYR A OH 1 ATOM 6278 N N . LEU A 1 785 ? -36.477 6.625 -43.045 1.00 17.22 ? 785 LEU A N 1 ATOM 6279 C CA . LEU A 1 785 ? -37.887 6.879 -43.372 1.00 17.84 ? 785 LEU A CA 1 ATOM 6280 C C . LEU A 1 785 ? -38.492 7.504 -42.126 1.00 17.18 ? 785 LEU A C 1 ATOM 6281 O O . LEU A 1 785 ? -38.312 6.985 -41.015 1.00 18.24 ? 785 LEU A O 1 ATOM 6282 C CB . LEU A 1 785 ? -38.575 5.566 -43.683 1.00 17.81 ? 785 LEU A CB 1 ATOM 6283 C CG . LEU A 1 785 ? -40.127 5.647 -43.674 1.00 20.19 ? 785 LEU A CG 1 ATOM 6284 C CD1 . LEU A 1 785 ? -40.573 6.472 -44.857 1.00 20.42 ? 785 LEU A CD1 1 ATOM 6285 C CD2 . LEU A 1 785 ? -40.692 4.284 -43.722 1.00 23.63 ? 785 LEU A CD2 1 ATOM 6286 N N . LEU A 1 786 ? -39.182 8.626 -42.268 1.00 17.38 ? 786 LEU A N 1 ATOM 6287 C CA . LEU A 1 786 ? -40.027 9.092 -41.163 1.00 17.91 ? 786 LEU A CA 1 ATOM 6288 C C . LEU A 1 786 ? -41.423 9.283 -41.722 1.00 19.16 ? 786 LEU A C 1 ATOM 6289 O O . LEU A 1 786 ? -41.592 10.023 -42.674 1.00 19.18 ? 786 LEU A O 1 ATOM 6290 C CB . LEU A 1 786 ? -39.504 10.396 -40.570 1.00 17.13 ? 786 LEU A CB 1 ATOM 6291 C CG . LEU A 1 786 ? -40.120 11.018 -39.304 1.00 17.60 ? 786 LEU A CG 1 ATOM 6292 C CD1 . LEU A 1 786 ? -39.942 10.065 -38.141 1.00 20.11 ? 786 LEU A CD1 1 ATOM 6293 C CD2 . LEU A 1 786 ? -39.521 12.401 -39.007 1.00 19.10 ? 786 LEU A CD2 1 ATOM 6294 N N . CYS A 1 787 ? -42.411 8.589 -41.185 1.00 20.22 ? 787 CYS A N 1 ATOM 6295 C CA . CYS A 1 787 ? -43.778 8.887 -41.610 1.00 22.11 ? 787 CYS A CA 1 ATOM 6296 C C . CYS A 1 787 ? -44.628 9.325 -40.442 1.00 21.96 ? 787 CYS A C 1 ATOM 6297 O O . CYS A 1 787 ? -44.269 9.125 -39.296 1.00 19.20 ? 787 CYS A O 1 ATOM 6298 C CB . CYS A 1 787 ? -44.433 7.734 -42.337 1.00 23.40 ? 787 CYS A CB 1 ATOM 6299 S SG . CYS A 1 787 ? -44.259 6.167 -41.613 1.00 32.35 ? 787 CYS A SG 1 ATOM 6300 N N . GLU A 1 788 ? -45.744 9.964 -40.779 1.00 21.53 ? 788 GLU A N 1 ATOM 6301 C CA . GLU A 1 788 ? -46.649 10.559 -39.817 1.00 23.29 ? 788 GLU A CA 1 ATOM 6302 C C . GLU A 1 788 ? -48.010 9.972 -40.093 1.00 22.32 ? 788 GLU A C 1 ATOM 6303 O O . GLU A 1 788 ? -48.400 9.763 -41.260 1.00 24.38 ? 788 GLU A O 1 ATOM 6304 C CB . GLU A 1 788 ? -46.631 12.094 -39.946 1.00 23.80 ? 788 GLU A CB 1 ATOM 6305 C CG . GLU A 1 788 ? -45.192 12.697 -39.696 1.00 32.30 ? 788 GLU A CG 1 ATOM 6306 C CD . GLU A 1 788 ? -44.730 12.695 -38.207 1.00 41.10 ? 788 GLU A CD 1 ATOM 6307 O OE1 . GLU A 1 788 ? -45.598 12.753 -37.292 1.00 46.48 ? 788 GLU A OE1 1 ATOM 6308 O OE2 . GLU A 1 788 ? -43.495 12.666 -37.941 1.00 41.80 ? 788 GLU A OE2 1 ATOM 6309 N N . PHE A 1 789 ? -48.721 9.644 -39.027 1.00 22.11 ? 789 PHE A N 1 ATOM 6310 C CA . PHE A 1 789 ? -50.068 9.113 -39.116 1.00 20.57 ? 789 PHE A CA 1 ATOM 6311 C C . PHE A 1 789 ? -50.961 10.131 -38.478 1.00 21.63 ? 789 PHE A C 1 ATOM 6312 O O . PHE A 1 789 ? -50.597 10.710 -37.456 1.00 20.89 ? 789 PHE A O 1 ATOM 6313 C CB . PHE A 1 789 ? -50.177 7.809 -38.316 1.00 20.69 ? 789 PHE A CB 1 ATOM 6314 C CG . PHE A 1 789 ? -49.066 6.848 -38.599 1.00 22.84 ? 789 PHE A CG 1 ATOM 6315 C CD1 . PHE A 1 789 ? -48.975 6.216 -39.856 1.00 21.74 ? 789 PHE A CD1 1 ATOM 6316 C CD2 . PHE A 1 789 ? -48.078 6.601 -37.635 1.00 22.55 ? 789 PHE A CD2 1 ATOM 6317 C CE1 . PHE A 1 789 ? -47.927 5.330 -40.144 1.00 22.73 ? 789 PHE A CE1 1 ATOM 6318 C CE2 . PHE A 1 789 ? -47.017 5.708 -37.904 1.00 24.11 ? 789 PHE A CE2 1 ATOM 6319 C CZ . PHE A 1 789 ? -46.941 5.069 -39.163 1.00 23.95 ? 789 PHE A CZ 1 ATOM 6320 N N . SER A 1 790 ? -52.117 10.381 -39.081 1.00 21.82 ? 790 SER A N 1 ATOM 6321 C CA . SER A 1 790 ? -53.163 11.161 -38.399 1.00 23.71 ? 790 SER A CA 1 ATOM 6322 C C . SER A 1 790 ? -54.558 10.701 -38.764 1.00 23.39 ? 790 SER A C 1 ATOM 6323 O O . SER A 1 790 ? -54.812 10.269 -39.882 1.00 23.92 ? 790 SER A O 1 ATOM 6324 C CB . SER A 1 790 ? -53.008 12.674 -38.628 1.00 24.72 ? 790 SER A CB 1 ATOM 6325 O OG . SER A 1 790 ? -52.974 12.978 -39.999 1.00 29.08 ? 790 SER A OG 1 ATOM 6326 N N . VAL A 1 791 ? -55.458 10.793 -37.800 1.00 24.03 ? 791 VAL A N 1 ATOM 6327 C CA . VAL A 1 791 ? -56.834 10.411 -37.983 1.00 25.39 ? 791 VAL A CA 1 ATOM 6328 C C . VAL A 1 791 ? -57.653 11.608 -37.537 1.00 26.83 ? 791 VAL A C 1 ATOM 6329 O O . VAL A 1 791 ? -57.427 12.143 -36.470 1.00 24.41 ? 791 VAL A O 1 ATOM 6330 C CB . VAL A 1 791 ? -57.179 9.162 -37.144 1.00 25.49 ? 791 VAL A CB 1 ATOM 6331 C CG1 . VAL A 1 791 ? -58.708 8.880 -37.177 1.00 25.08 ? 791 VAL A CG1 1 ATOM 6332 C CG2 . VAL A 1 791 ? -56.374 7.980 -37.636 1.00 24.74 ? 791 VAL A CG2 1 ATOM 6333 N N . THR A 1 792 ? -58.530 12.088 -38.405 1.00 29.65 ? 792 THR A N 1 ATOM 6334 C CA . THR A 1 792 ? -59.482 13.118 -38.010 1.00 33.65 ? 792 THR A CA 1 ATOM 6335 C C . THR A 1 792 ? -60.657 12.778 -38.833 1.00 34.92 ? 792 THR A C 1 ATOM 6336 O O . THR A 1 792 ? -60.543 12.697 -40.074 1.00 35.42 ? 792 THR A O 1 ATOM 6337 C CB . THR A 1 792 ? -59.072 14.565 -38.348 1.00 33.25 ? 792 THR A CB 1 ATOM 6338 O OG1 . THR A 1 792 ? -58.569 14.609 -39.676 1.00 36.84 ? 792 THR A OG1 1 ATOM 6339 C CG2 . THR A 1 792 ? -58.018 15.096 -37.406 1.00 37.07 ? 792 THR A CG2 1 ATOM 6340 N N . GLN A 1 793 ? -61.761 12.606 -38.101 1.00 36.73 ? 793 GLN A N 1 ATOM 6341 C CA . GLN A 1 793 ? -62.997 11.903 -38.473 1.00 38.14 ? 793 GLN A CA 1 ATOM 6342 C C . GLN A 1 793 ? -63.070 11.196 -39.837 1.00 37.17 ? 793 GLN A C 1 ATOM 6343 O O . GLN A 1 793 ? -62.939 11.828 -40.908 1.00 37.23 ? 793 GLN A O 1 ATOM 6344 C CB . GLN A 1 793 ? -64.283 12.726 -38.140 1.00 39.33 ? 793 GLN A CB 1 ATOM 6345 C CG . GLN A 1 793 ? -64.082 14.203 -37.629 1.00 43.33 ? 793 GLN A CG 1 ATOM 6346 C CD . GLN A 1 793 ? -62.946 14.347 -36.588 1.00 45.36 ? 793 GLN A CD 1 ATOM 6347 O OE1 . GLN A 1 793 ? -62.922 13.648 -35.571 1.00 47.49 ? 793 GLN A OE1 1 ATOM 6348 N NE2 . GLN A 1 793 ? -62.000 15.243 -36.863 1.00 45.88 ? 793 GLN A NE2 1 ATOM 6349 N N . ASN A 1 794 ? -63.294 9.880 -39.771 1.00 35.70 ? 794 ASN A N 1 ATOM 6350 C CA . ASN A 1 794 ? -63.525 9.082 -40.974 1.00 34.93 ? 794 ASN A CA 1 ATOM 6351 C C . ASN A 1 794 ? -62.258 8.886 -41.801 1.00 32.36 ? 794 ASN A C 1 ATOM 6352 O O . ASN A 1 794 ? -62.360 8.383 -42.903 1.00 31.40 ? 794 ASN A O 1 ATOM 6353 C CB . ASN A 1 794 ? -64.551 9.759 -41.927 1.00 35.82 ? 794 ASN A CB 1 ATOM 6354 C CG . ASN A 1 794 ? -65.924 10.040 -41.266 1.00 40.40 ? 794 ASN A CG 1 ATOM 6355 O OD1 . ASN A 1 794 ? -66.214 11.183 -40.846 1.00 44.37 ? 794 ASN A OD1 1 ATOM 6356 N ND2 . ASN A 1 794 ? -66.773 9.013 -41.202 1.00 40.54 ? 794 ASN A ND2 1 ATOM 6357 N N . ARG A 1 795 ? -61.090 9.330 -41.337 1.00 30.68 ? 795 ARG A N 1 ATOM 6358 C CA . ARG A 1 795 ? -59.929 9.347 -42.247 1.00 29.32 ? 795 ARG A CA 1 ATOM 6359 C C . ARG A 1 795 ? -58.564 9.169 -41.556 1.00 27.63 ? 795 ARG A C 1 ATOM 6360 O O . ARG A 1 795 ? -58.204 9.990 -40.717 1.00 27.06 ? 795 ARG A O 1 ATOM 6361 C CB . ARG A 1 795 ? -59.961 10.660 -43.035 1.00 29.49 ? 795 ARG A CB 1 ATOM 6362 C CG . ARG A 1 795 ? -58.929 10.854 -44.131 1.00 30.83 ? 795 ARG A CG 1 ATOM 6363 C CD . ARG A 1 795 ? -59.267 12.139 -44.914 1.00 33.04 ? 795 ARG A CD 1 ATOM 6364 N NE . ARG A 1 795 ? -58.338 12.394 -46.017 1.00 44.49 ? 795 ARG A NE 1 ATOM 6365 C CZ . ARG A 1 795 ? -58.692 12.878 -47.215 1.00 46.97 ? 795 ARG A CZ 1 ATOM 6366 N NH1 . ARG A 1 795 ? -59.973 13.152 -47.477 1.00 49.95 ? 795 ARG A NH1 1 ATOM 6367 N NH2 . ARG A 1 795 ? -57.771 13.066 -48.164 1.00 47.14 ? 795 ARG A NH2 1 ATOM 6368 N N . LEU A 1 796 ? -57.816 8.124 -41.935 1.00 24.96 ? 796 LEU A N 1 ATOM 6369 C CA . LEU A 1 796 ? -56.407 7.964 -41.545 1.00 24.03 ? 796 LEU A CA 1 ATOM 6370 C C . LEU A 1 796 ? -55.587 8.412 -42.722 1.00 24.22 ? 796 LEU A C 1 ATOM 6371 O O . LEU A 1 796 ? -55.845 7.988 -43.850 1.00 24.60 ? 796 LEU A O 1 ATOM 6372 C CB . LEU A 1 796 ? -56.057 6.493 -41.236 1.00 23.90 ? 796 LEU A CB 1 ATOM 6373 C CG . LEU A 1 796 ? -54.563 6.105 -41.274 1.00 22.12 ? 796 LEU A CG 1 ATOM 6374 C CD1 . LEU A 1 796 ? -53.852 6.672 -40.050 1.00 17.27 ? 796 LEU A CD1 1 ATOM 6375 C CD2 . LEU A 1 796 ? -54.419 4.599 -41.311 1.00 21.92 ? 796 LEU A CD2 1 ATOM 6376 N N . GLU A 1 797 ? -54.615 9.277 -42.476 1.00 24.94 ? 797 GLU A N 1 ATOM 6377 C CA . GLU A 1 797 ? -53.655 9.656 -43.489 1.00 26.73 ? 797 GLU A CA 1 ATOM 6378 C C . GLU A 1 797 ? -52.291 9.161 -43.050 1.00 25.02 ? 797 GLU A C 1 ATOM 6379 O O . GLU A 1 797 ? -51.912 9.317 -41.877 1.00 22.96 ? 797 GLU A O 1 ATOM 6380 C CB . GLU A 1 797 ? -53.631 11.185 -43.686 1.00 27.22 ? 797 GLU A CB 1 ATOM 6381 C CG . GLU A 1 797 ? -55.011 11.750 -44.107 1.00 31.97 ? 797 GLU A CG 1 ATOM 6382 C CD . GLU A 1 797 ? -55.163 13.276 -43.964 1.00 34.30 ? 797 GLU A CD 1 ATOM 6383 O OE1 . GLU A 1 797 ? -54.154 13.986 -43.667 1.00 42.09 ? 797 GLU A OE1 1 ATOM 6384 O OE2 . GLU A 1 797 ? -56.317 13.775 -44.173 1.00 43.42 ? 797 GLU A OE2 1 ATOM 6385 N N . VAL A 1 798 ? -51.578 8.535 -43.990 1.00 24.85 ? 798 VAL A N 1 ATOM 6386 C CA . VAL A 1 798 ? -50.173 8.143 -43.805 1.00 23.86 ? 798 VAL A CA 1 ATOM 6387 C C . VAL A 1 798 ? -49.349 9.064 -44.717 1.00 24.02 ? 798 VAL A C 1 ATOM 6388 O O . VAL A 1 798 ? -49.547 9.069 -45.937 1.00 23.38 ? 798 VAL A O 1 ATOM 6389 C CB . VAL A 1 798 ? -49.919 6.632 -44.158 1.00 24.17 ? 798 VAL A CB 1 ATOM 6390 C CG1 . VAL A 1 798 ? -48.466 6.241 -43.806 1.00 22.84 ? 798 VAL A CG1 1 ATOM 6391 C CG2 . VAL A 1 798 ? -50.887 5.727 -43.441 1.00 24.99 ? 798 VAL A CG2 1 ATOM 6392 N N . ASN A 1 799 ? -48.511 9.900 -44.110 1.00 23.62 ? 799 ASN A N 1 ATOM 6393 C CA . ASN A 1 799 ? -47.803 10.989 -44.747 1.00 25.43 ? 799 ASN A CA 1 ATOM 6394 C C . ASN A 1 799 ? -46.300 10.746 -44.592 1.00 25.37 ? 799 ASN A C 1 ATOM 6395 O O . ASN A 1 799 ? -45.846 10.450 -43.501 1.00 25.84 ? 799 ASN A O 1 ATOM 6396 C CB . ASN A 1 799 ? -48.078 12.275 -43.964 1.00 26.74 ? 799 ASN A CB 1 ATOM 6397 C CG . ASN A 1 799 ? -48.795 13.332 -44.770 1.00 32.99 ? 799 ASN A CG 1 ATOM 6398 O OD1 . ASN A 1 799 ? -48.221 14.393 -45.086 1.00 39.13 ? 799 ASN A OD1 1 ATOM 6399 N ND2 . ASN A 1 799 ? -50.080 13.093 -45.053 1.00 36.77 ? 799 ASN A ND2 1 ATOM 6400 N N . ILE A 1 800 ? -45.530 10.913 -45.650 1.00 24.93 ? 800 ILE A N 1 ATOM 6401 C CA . ILE A 1 800 ? -44.097 10.641 -45.595 1.00 25.29 ? 800 ILE A CA 1 ATOM 6402 C C . ILE A 1 800 ? -43.353 11.956 -45.505 1.00 25.40 ? 800 ILE A C 1 ATOM 6403 O O . ILE A 1 800 ? -43.457 12.801 -46.396 1.00 25.03 ? 800 ILE A O 1 ATOM 6404 C CB . ILE A 1 800 ? -43.614 9.873 -46.859 1.00 25.20 ? 800 ILE A CB 1 ATOM 6405 C CG1 . ILE A 1 800 ? -44.549 8.709 -47.187 1.00 25.03 ? 800 ILE A CG1 1 ATOM 6406 C CG2 . ILE A 1 800 ? -42.210 9.376 -46.684 1.00 24.96 ? 800 ILE A CG2 1 ATOM 6407 C CD1 . ILE A 1 800 ? -44.786 7.723 -46.039 1.00 26.18 ? 800 ILE A CD1 1 ATOM 6408 N N . SER A 1 801 ? -42.604 12.158 -44.431 1.00 25.30 ? 801 SER A N 1 ATOM 6409 C CA . SER A 1 801 ? -41.860 13.382 -44.344 1.00 26.62 ? 801 SER A CA 1 ATOM 6410 C C . SER A 1 801 ? -40.394 13.194 -44.741 1.00 26.71 ? 801 SER A C 1 ATOM 6411 O O . SER A 1 801 ? -39.790 14.122 -45.213 1.00 28.28 ? 801 SER A O 1 ATOM 6412 C CB . SER A 1 801 ? -42.009 14.044 -42.982 1.00 27.31 ? 801 SER A CB 1 ATOM 6413 O OG . SER A 1 801 ? -41.136 13.467 -42.031 1.00 29.97 ? 801 SER A OG 1 ATOM 6414 N N . GLN A 1 802 ? -39.829 12.008 -44.562 1.00 25.90 ? 802 GLN A N 1 ATOM 6415 C CA . GLN A 1 802 ? -38.454 11.759 -45.026 1.00 25.27 ? 802 GLN A CA 1 ATOM 6416 C C . GLN A 1 802 ? -38.486 10.384 -45.607 1.00 25.26 ? 802 GLN A C 1 ATOM 6417 O O . GLN A 1 802 ? -39.086 9.457 -45.028 1.00 23.74 ? 802 GLN A O 1 ATOM 6418 C CB . GLN A 1 802 ? -37.443 11.844 -43.877 1.00 25.33 ? 802 GLN A CB 1 ATOM 6419 C CG . GLN A 1 802 ? -35.964 11.461 -44.219 1.00 27.24 ? 802 GLN A CG 1 ATOM 6420 C CD . GLN A 1 802 ? -35.218 12.563 -44.910 1.00 32.21 ? 802 GLN A CD 1 ATOM 6421 O OE1 . GLN A 1 802 ? -34.381 12.326 -45.802 1.00 34.29 ? 802 GLN A OE1 1 ATOM 6422 N NE2 . GLN A 1 802 ? -35.524 13.778 -44.536 1.00 31.69 ? 802 GLN A NE2 1 ATOM 6423 N N . SER A 1 803 ? -37.812 10.222 -46.734 1.00 25.88 ? 803 SER A N 1 ATOM 6424 C CA . SER A 1 803 ? -37.988 9.032 -47.501 1.00 27.76 ? 803 SER A CA 1 ATOM 6425 C C . SER A 1 803 ? -36.681 8.569 -48.143 1.00 27.66 ? 803 SER A C 1 ATOM 6426 O O . SER A 1 803 ? -36.640 8.280 -49.334 1.00 28.74 ? 803 SER A O 1 ATOM 6427 C CB . SER A 1 803 ? -39.031 9.331 -48.578 1.00 28.51 ? 803 SER A CB 1 ATOM 6428 O OG . SER A 1 803 ? -39.252 8.164 -49.313 1.00 33.26 ? 803 SER A OG 1 ATOM 6429 N N . THR A 1 804 ? -35.611 8.501 -47.369 1.00 26.16 ? 804 THR A N 1 ATOM 6430 C CA . THR A 1 804 ? -34.330 8.155 -47.958 1.00 25.80 ? 804 THR A CA 1 ATOM 6431 C C . THR A 1 804 ? -33.839 6.763 -47.577 1.00 25.54 ? 804 THR A C 1 ATOM 6432 O O . THR A 1 804 ? -32.685 6.432 -47.809 1.00 25.99 ? 804 THR A O 1 ATOM 6433 C CB . THR A 1 804 ? -33.282 9.208 -47.645 1.00 25.46 ? 804 THR A CB 1 ATOM 6434 O OG1 . THR A 1 804 ? -33.389 9.588 -46.268 1.00 25.45 ? 804 THR A OG1 1 ATOM 6435 C CG2 . THR A 1 804 ? -33.512 10.450 -48.494 1.00 25.86 ? 804 THR A CG2 1 ATOM 6436 N N . TYR A 1 805 ? -34.714 5.933 -47.022 1.00 24.15 ? 805 TYR A N 1 ATOM 6437 C CA . TYR A 1 805 ? -34.353 4.561 -46.786 1.00 24.66 ? 805 TYR A CA 1 ATOM 6438 C C . TYR A 1 805 ? -35.539 3.686 -47.103 1.00 25.12 ? 805 TYR A C 1 ATOM 6439 O O . TYR A 1 805 ? -36.627 3.907 -46.583 1.00 25.73 ? 805 TYR A O 1 ATOM 6440 C CB . TYR A 1 805 ? -33.912 4.314 -45.327 1.00 24.05 ? 805 TYR A CB 1 ATOM 6441 C CG . TYR A 1 805 ? -33.612 2.856 -45.051 1.00 23.56 ? 805 TYR A CG 1 ATOM 6442 C CD1 . TYR A 1 805 ? -32.427 2.257 -45.541 1.00 20.88 ? 805 TYR A CD1 1 ATOM 6443 C CD2 . TYR A 1 805 ? -34.515 2.059 -44.344 1.00 20.33 ? 805 TYR A CD2 1 ATOM 6444 C CE1 . TYR A 1 805 ? -32.166 0.906 -45.310 1.00 22.01 ? 805 TYR A CE1 1 ATOM 6445 C CE2 . TYR A 1 805 ? -34.258 0.721 -44.112 1.00 21.13 ? 805 TYR A CE2 1 ATOM 6446 C CZ . TYR A 1 805 ? -33.091 0.155 -44.585 1.00 22.97 ? 805 TYR A CZ 1 ATOM 6447 O OH . TYR A 1 805 ? -32.859 -1.164 -44.349 1.00 23.01 ? 805 TYR A OH 1 ATOM 6448 N N . LYS A 1 806 ? -35.334 2.688 -47.949 1.00 25.36 ? 806 LYS A N 1 ATOM 6449 C CA . LYS A 1 806 ? -36.401 1.752 -48.214 1.00 25.44 ? 806 LYS A CA 1 ATOM 6450 C C . LYS A 1 806 ? -35.915 0.381 -47.788 1.00 24.62 ? 806 LYS A C 1 ATOM 6451 O O . LYS A 1 806 ? -34.950 -0.143 -48.344 1.00 24.99 ? 806 LYS A O 1 ATOM 6452 C CB . LYS A 1 806 ? -36.833 1.756 -49.688 1.00 26.68 ? 806 LYS A CB 1 ATOM 6453 C CG . LYS A 1 806 ? -38.057 0.815 -49.883 1.00 27.63 ? 806 LYS A CG 1 ATOM 6454 C CD . LYS A 1 806 ? -39.086 1.309 -50.896 1.00 29.90 ? 806 LYS A CD 1 ATOM 6455 C CE . LYS A 1 806 ? -40.372 0.462 -50.791 1.00 30.16 ? 806 LYS A CE 1 ATOM 6456 N NZ . LYS A 1 806 ? -41.362 0.729 -51.870 1.00 34.71 ? 806 LYS A NZ 1 ATOM 6457 N N . ASP A 1 807 ? -36.586 -0.183 -46.788 1.00 22.68 ? 807 ASP A N 1 ATOM 6458 C CA . ASP A 1 807 ? -36.282 -1.491 -46.255 1.00 21.55 ? 807 ASP A CA 1 ATOM 6459 C C . ASP A 1 807 ? -36.499 -2.581 -47.320 1.00 22.41 ? 807 ASP A C 1 ATOM 6460 O O . ASP A 1 807 ? -37.556 -2.645 -47.966 1.00 20.40 ? 807 ASP A O 1 ATOM 6461 C CB . ASP A 1 807 ? -37.169 -1.754 -45.032 1.00 21.95 ? 807 ASP A CB 1 ATOM 6462 C CG . ASP A 1 807 ? -36.741 -2.982 -44.257 1.00 23.52 ? 807 ASP A CG 1 ATOM 6463 O OD1 . ASP A 1 807 ? -36.783 -4.086 -44.837 1.00 25.82 ? 807 ASP A OD1 1 ATOM 6464 O OD2 . ASP A 1 807 ? -36.370 -2.853 -43.073 1.00 25.09 ? 807 ASP A OD2 1 ATOM 6465 N N . PRO A 1 808 ? -35.487 -3.435 -47.535 1.00 23.14 ? 808 PRO A N 1 ATOM 6466 C CA . PRO A 1 808 ? -35.626 -4.418 -48.618 1.00 23.32 ? 808 PRO A CA 1 ATOM 6467 C C . PRO A 1 808 ? -36.544 -5.598 -48.322 1.00 23.06 ? 808 PRO A C 1 ATOM 6468 O O . PRO A 1 808 ? -36.764 -6.439 -49.200 1.00 23.97 ? 808 PRO A O 1 ATOM 6469 C CB . PRO A 1 808 ? -34.187 -4.908 -48.787 1.00 22.33 ? 808 PRO A CB 1 ATOM 6470 C CG . PRO A 1 808 ? -33.659 -4.869 -47.389 1.00 24.40 ? 808 PRO A CG 1 ATOM 6471 C CD . PRO A 1 808 ? -34.168 -3.543 -46.872 1.00 23.75 ? 808 PRO A CD 1 ATOM 6472 N N . ASN A 1 809 ? -37.070 -5.687 -47.103 1.00 23.03 ? 809 ASN A N 1 ATOM 6473 C CA . ASN A 1 809 ? -37.948 -6.799 -46.745 1.00 22.83 ? 809 ASN A CA 1 ATOM 6474 C C . ASN A 1 809 ? -39.427 -6.666 -47.093 1.00 23.23 ? 809 ASN A C 1 ATOM 6475 O O . ASN A 1 809 ? -40.233 -7.370 -46.514 1.00 23.95 ? 809 ASN A O 1 ATOM 6476 C CB . ASN A 1 809 ? -37.781 -7.153 -45.269 1.00 22.49 ? 809 ASN A CB 1 ATOM 6477 C CG . ASN A 1 809 ? -36.401 -7.701 -44.975 1.00 24.07 ? 809 ASN A CG 1 ATOM 6478 O OD1 . ASN A 1 809 ? -35.654 -7.145 -44.184 1.00 28.68 ? 809 ASN A OD1 1 ATOM 6479 N ND2 . ASN A 1 809 ? -36.043 -8.750 -45.662 1.00 23.42 ? 809 ASN A ND2 1 ATOM 6480 N N . ASN A 1 810 ? -39.793 -5.790 -48.011 1.00 24.06 ? 810 ASN A N 1 ATOM 6481 C CA . ASN A 1 810 ? -41.222 -5.695 -48.428 1.00 24.42 ? 810 ASN A CA 1 ATOM 6482 C C . ASN A 1 810 ? -42.156 -5.444 -47.232 1.00 23.28 ? 810 ASN A C 1 ATOM 6483 O O . ASN A 1 810 ? -43.168 -6.138 -47.073 1.00 24.12 ? 810 ASN A O 1 ATOM 6484 C CB . ASN A 1 810 ? -41.688 -6.974 -49.199 1.00 25.00 ? 810 ASN A CB 1 ATOM 6485 C CG . ASN A 1 810 ? -43.085 -6.826 -49.872 1.00 26.46 ? 810 ASN A CG 1 ATOM 6486 O OD1 . ASN A 1 810 ? -43.434 -5.751 -50.373 1.00 33.24 ? 810 ASN A OD1 1 ATOM 6487 N ND2 . ASN A 1 810 ? -43.856 -7.933 -49.924 1.00 27.51 ? 810 ASN A ND2 1 ATOM 6488 N N . LEU A 1 811 ? -41.812 -4.484 -46.378 1.00 21.90 ? 811 LEU A N 1 ATOM 6489 C CA . LEU A 1 811 ? -42.566 -4.298 -45.132 1.00 20.13 ? 811 LEU A CA 1 ATOM 6490 C C . LEU A 1 811 ? -43.844 -3.543 -45.427 1.00 19.71 ? 811 LEU A C 1 ATOM 6491 O O . LEU A 1 811 ? -43.859 -2.580 -46.209 1.00 19.15 ? 811 LEU A O 1 ATOM 6492 C CB . LEU A 1 811 ? -41.736 -3.534 -44.092 1.00 20.12 ? 811 LEU A CB 1 ATOM 6493 C CG . LEU A 1 811 ? -40.447 -4.215 -43.598 1.00 20.27 ? 811 LEU A CG 1 ATOM 6494 C CD1 . LEU A 1 811 ? -39.722 -3.347 -42.532 1.00 20.76 ? 811 LEU A CD1 1 ATOM 6495 C CD2 . LEU A 1 811 ? -40.708 -5.628 -43.077 1.00 16.87 ? 811 LEU A CD2 1 ATOM 6496 N N . ALA A 1 812 ? -44.918 -3.919 -44.746 1.00 19.81 ? 812 ALA A N 1 ATOM 6497 C CA . ALA A 1 812 ? -46.135 -3.176 -44.965 1.00 19.73 ? 812 ALA A CA 1 ATOM 6498 C C . ALA A 1 812 ? -47.013 -3.299 -43.734 1.00 19.81 ? 812 ALA A C 1 ATOM 6499 O O . ALA A 1 812 ? -46.915 -4.268 -42.964 1.00 19.23 ? 812 ALA A O 1 ATOM 6500 C CB . ALA A 1 812 ? -46.862 -3.750 -46.202 1.00 19.53 ? 812 ALA A CB 1 ATOM 6501 N N . PHE A 1 813 ? -47.878 -2.316 -43.560 1.00 20.05 ? 813 PHE A N 1 ATOM 6502 C CA . PHE A 1 813 ? -48.896 -2.392 -42.530 1.00 19.89 ? 813 PHE A CA 1 ATOM 6503 C C . PHE A 1 813 ? -49.967 -3.320 -43.048 1.00 20.93 ? 813 PHE A C 1 ATOM 6504 O O . PHE A 1 813 ? -50.595 -3.039 -44.086 1.00 21.64 ? 813 PHE A O 1 ATOM 6505 C CB . PHE A 1 813 ? -49.467 -1.013 -42.222 1.00 20.41 ? 813 PHE A CB 1 ATOM 6506 C CG . PHE A 1 813 ? -48.442 -0.027 -41.770 1.00 21.88 ? 813 PHE A CG 1 ATOM 6507 C CD1 . PHE A 1 813 ? -47.991 -0.032 -40.446 1.00 20.47 ? 813 PHE A CD1 1 ATOM 6508 C CD2 . PHE A 1 813 ? -47.902 0.891 -42.671 1.00 22.18 ? 813 PHE A CD2 1 ATOM 6509 C CE1 . PHE A 1 813 ? -47.004 0.881 -40.032 1.00 19.05 ? 813 PHE A CE1 1 ATOM 6510 C CE2 . PHE A 1 813 ? -46.930 1.805 -42.270 1.00 24.40 ? 813 PHE A CE2 1 ATOM 6511 C CZ . PHE A 1 813 ? -46.473 1.801 -40.934 1.00 22.08 ? 813 PHE A CZ 1 ATOM 6512 N N . ASN A 1 814 ? -50.173 -4.434 -42.360 1.00 20.46 ? 814 ASN A N 1 ATOM 6513 C CA . ASN A 1 814 ? -51.203 -5.340 -42.798 1.00 21.23 ? 814 ASN A CA 1 ATOM 6514 C C . ASN A 1 814 ? -52.355 -5.415 -41.823 1.00 20.99 ? 814 ASN A C 1 ATOM 6515 O O . ASN A 1 814 ? -53.243 -6.223 -42.009 1.00 19.75 ? 814 ASN A O 1 ATOM 6516 C CB . ASN A 1 814 ? -50.664 -6.722 -43.141 1.00 22.87 ? 814 ASN A CB 1 ATOM 6517 C CG . ASN A 1 814 ? -50.344 -7.540 -41.935 1.00 26.77 ? 814 ASN A CG 1 ATOM 6518 O OD1 . ASN A 1 814 ? -50.224 -7.026 -40.807 1.00 31.91 ? 814 ASN A OD1 1 ATOM 6519 N ND2 . ASN A 1 814 ? -50.185 -8.853 -42.151 1.00 33.52 ? 814 ASN A ND2 1 ATOM 6520 N N . GLU A 1 815 ? -52.315 -4.593 -40.774 1.00 20.61 ? 815 GLU A N 1 ATOM 6521 C CA . GLU A 1 815 ? -53.407 -4.589 -39.792 1.00 23.17 ? 815 GLU A CA 1 ATOM 6522 C C . GLU A 1 815 ? -53.486 -3.198 -39.184 1.00 21.93 ? 815 GLU A C 1 ATOM 6523 O O . GLU A 1 815 ? -52.453 -2.594 -38.834 1.00 20.37 ? 815 GLU A O 1 ATOM 6524 C CB . GLU A 1 815 ? -53.200 -5.650 -38.694 1.00 22.74 ? 815 GLU A CB 1 ATOM 6525 C CG . GLU A 1 815 ? -54.412 -5.810 -37.723 1.00 27.00 ? 815 GLU A CG 1 ATOM 6526 C CD . GLU A 1 815 ? -54.276 -6.979 -36.744 1.00 29.54 ? 815 GLU A CD 1 ATOM 6527 O OE1 . GLU A 1 815 ? -53.891 -8.112 -37.148 1.00 38.33 ? 815 GLU A OE1 1 ATOM 6528 O OE2 . GLU A 1 815 ? -54.588 -6.767 -35.545 1.00 39.98 ? 815 GLU A OE2 1 ATOM 6529 N N . ILE A 1 816 ? -54.715 -2.685 -39.089 1.00 21.00 ? 816 ILE A N 1 ATOM 6530 C CA . ILE A 1 816 ? -54.972 -1.419 -38.397 1.00 20.11 ? 816 ILE A CA 1 ATOM 6531 C C . ILE A 1 816 ? -56.039 -1.708 -37.335 1.00 20.94 ? 816 ILE A C 1 ATOM 6532 O O . ILE A 1 816 ? -57.119 -2.188 -37.661 1.00 19.22 ? 816 ILE A O 1 ATOM 6533 C CB . ILE A 1 816 ? -55.452 -0.324 -39.345 1.00 20.15 ? 816 ILE A CB 1 ATOM 6534 C CG1 . ILE A 1 816 ? -54.358 -0.005 -40.400 1.00 21.93 ? 816 ILE A CG1 1 ATOM 6535 C CG2 . ILE A 1 816 ? -55.805 0.935 -38.556 1.00 19.82 ? 816 ILE A CG2 1 ATOM 6536 C CD1 . ILE A 1 816 ? -54.817 0.918 -41.538 1.00 20.45 ? 816 ILE A CD1 1 ATOM 6537 N N . LYS A 1 817 ? -55.716 -1.443 -36.069 1.00 20.05 ? 817 LYS A N 1 ATOM 6538 C CA . LYS A 1 817 ? -56.674 -1.626 -35.000 1.00 20.71 ? 817 LYS A CA 1 ATOM 6539 C C . LYS A 1 817 ? -57.101 -0.252 -34.503 1.00 20.75 ? 817 LYS A C 1 ATOM 6540 O O . LYS A 1 817 ? -56.267 0.544 -34.127 1.00 20.62 ? 817 LYS A O 1 ATOM 6541 C CB . LYS A 1 817 ? -56.050 -2.462 -33.880 1.00 20.52 ? 817 LYS A CB 1 ATOM 6542 C CG . LYS A 1 817 ? -56.905 -2.704 -32.663 1.00 22.81 ? 817 LYS A CG 1 ATOM 6543 C CD . LYS A 1 817 ? -56.248 -3.774 -31.866 1.00 27.20 ? 817 LYS A CD 1 ATOM 6544 C CE . LYS A 1 817 ? -56.972 -4.110 -30.621 1.00 33.41 ? 817 LYS A CE 1 ATOM 6545 N NZ . LYS A 1 817 ? -55.985 -4.799 -29.671 1.00 36.25 ? 817 LYS A NZ 1 ATOM 6546 N N . ILE A 1 818 ? -58.414 0.013 -34.509 1.00 20.23 ? 818 ILE A N 1 ATOM 6547 C CA . ILE A 1 818 ? -58.935 1.323 -34.095 1.00 20.26 ? 818 ILE A CA 1 ATOM 6548 C C . ILE A 1 818 ? -59.700 1.130 -32.806 1.00 20.25 ? 818 ILE A C 1 ATOM 6549 O O . ILE A 1 818 ? -60.587 0.296 -32.752 1.00 19.45 ? 818 ILE A O 1 ATOM 6550 C CB . ILE A 1 818 ? -59.878 1.923 -35.157 1.00 20.40 ? 818 ILE A CB 1 ATOM 6551 C CG1 . ILE A 1 818 ? -59.156 2.043 -36.518 1.00 21.06 ? 818 ILE A CG1 1 ATOM 6552 C CG2 . ILE A 1 818 ? -60.443 3.254 -34.668 1.00 19.09 ? 818 ILE A CG2 1 ATOM 6553 C CD1 . ILE A 1 818 ? -60.094 2.355 -37.705 1.00 22.78 ? 818 ILE A CD1 1 ATOM 6554 N N . LEU A 1 819 ? -59.329 1.887 -31.772 1.00 19.02 ? 819 LEU A N 1 ATOM 6555 C CA . LEU A 1 819 ? -59.932 1.772 -30.444 1.00 19.35 ? 819 LEU A CA 1 ATOM 6556 C C . LEU A 1 819 ? -60.877 2.971 -30.248 1.00 19.41 ? 819 LEU A C 1 ATOM 6557 O O . LEU A 1 819 ? -60.580 4.070 -30.688 1.00 19.10 ? 819 LEU A O 1 ATOM 6558 C CB . LEU A 1 819 ? -58.831 1.763 -29.345 1.00 19.18 ? 819 LEU A CB 1 ATOM 6559 C CG . LEU A 1 819 ? -57.663 0.774 -29.530 1.00 18.84 ? 819 LEU A CG 1 ATOM 6560 C CD1 . LEU A 1 819 ? -56.569 0.852 -28.403 1.00 18.02 ? 819 LEU A CD1 1 ATOM 6561 C CD2 . LEU A 1 819 ? -58.172 -0.676 -29.633 1.00 14.97 ? 819 LEU A CD2 1 ATOM 6562 N N . GLY A 1 820 ? -62.014 2.738 -29.610 1.00 19.95 ? 820 GLY A N 1 ATOM 6563 C CA . GLY A 1 820 ? -62.945 3.824 -29.245 1.00 20.79 ? 820 GLY A CA 1 ATOM 6564 C C . GLY A 1 820 ? -63.729 4.296 -30.458 1.00 22.11 ? 820 GLY A C 1 ATOM 6565 O O . GLY A 1 820 ? -64.056 5.480 -30.582 1.00 22.89 ? 820 GLY A O 1 ATOM 6566 N N . THR A 1 821 ? -64.020 3.373 -31.370 1.00 22.53 ? 821 THR A N 1 ATOM 6567 C CA . THR A 1 821 ? -64.776 3.709 -32.573 1.00 22.87 ? 821 THR A CA 1 ATOM 6568 C C . THR A 1 821 ? -66.164 3.046 -32.673 1.00 22.63 ? 821 THR A C 1 ATOM 6569 O O . THR A 1 821 ? -66.393 1.935 -32.177 1.00 20.99 ? 821 THR A O 1 ATOM 6570 C CB . THR A 1 821 ? -63.970 3.406 -33.842 1.00 23.73 ? 821 THR A CB 1 ATOM 6571 O OG1 . THR A 1 821 ? -64.719 3.848 -34.979 1.00 25.17 ? 821 THR A OG1 1 ATOM 6572 C CG2 . THR A 1 821 ? -63.677 1.896 -33.954 1.00 21.07 ? 821 THR A CG2 1 ATOM 6573 N N . GLU A 1 822 ? -67.090 3.762 -33.305 1.00 23.51 ? 822 GLU A N 1 ATOM 6574 C CA . GLU A 1 822 ? -68.340 3.192 -33.753 1.00 25.76 ? 822 GLU A CA 1 ATOM 6575 C C . GLU A 1 822 ? -68.003 2.312 -34.963 1.00 26.50 ? 822 GLU A C 1 ATOM 6576 O O . GLU A 1 822 ? -66.921 2.455 -35.558 1.00 26.01 ? 822 GLU A O 1 ATOM 6577 C CB . GLU A 1 822 ? -69.328 4.315 -34.138 1.00 25.85 ? 822 GLU A CB 1 ATOM 6578 C CG . GLU A 1 822 ? -69.887 5.083 -32.910 1.00 28.77 ? 822 GLU A CG 1 ATOM 6579 C CD . GLU A 1 822 ? -70.397 4.164 -31.808 1.00 33.91 ? 822 GLU A CD 1 ATOM 6580 O OE1 . GLU A 1 822 ? -71.296 3.327 -32.068 1.00 38.62 ? 822 GLU A OE1 1 ATOM 6581 O OE2 . GLU A 1 822 ? -69.906 4.278 -30.665 1.00 37.18 ? 822 GLU A OE2 1 ATOM 6582 N N . GLU A 1 823 ? -68.905 1.410 -35.333 1.00 27.86 ? 823 GLU A N 1 ATOM 6583 C CA . GLU A 1 823 ? -68.654 0.524 -36.485 1.00 28.90 ? 823 GLU A CA 1 ATOM 6584 C C . GLU A 1 823 ? -68.280 1.281 -37.761 1.00 29.28 ? 823 GLU A C 1 ATOM 6585 O O . GLU A 1 823 ? -69.098 2.060 -38.272 1.00 29.18 ? 823 GLU A O 1 ATOM 6586 C CB . GLU A 1 823 ? -69.875 -0.360 -36.763 1.00 29.74 ? 823 GLU A CB 1 ATOM 6587 C CG . GLU A 1 823 ? -69.531 -1.472 -37.736 1.00 32.33 ? 823 GLU A CG 1 ATOM 6588 C CD . GLU A 1 823 ? -70.531 -2.612 -37.783 1.00 36.57 ? 823 GLU A CD 1 ATOM 6589 O OE1 . GLU A 1 823 ? -71.654 -2.499 -37.231 1.00 37.00 ? 823 GLU A OE1 1 ATOM 6590 O OE2 . GLU A 1 823 ? -70.176 -3.628 -38.419 1.00 37.50 ? 823 GLU A OE2 1 ATOM 6591 N N . PRO A 1 824 ? -67.055 1.066 -38.285 1.00 29.60 ? 824 PRO A N 1 ATOM 6592 C CA . PRO A 1 824 ? -66.768 1.634 -39.602 1.00 30.87 ? 824 PRO A CA 1 ATOM 6593 C C . PRO A 1 824 ? -67.467 0.864 -40.723 1.00 32.42 ? 824 PRO A C 1 ATOM 6594 O O . PRO A 1 824 ? -67.713 -0.348 -40.607 1.00 33.80 ? 824 PRO A O 1 ATOM 6595 C CB . PRO A 1 824 ? -65.251 1.489 -39.763 1.00 30.51 ? 824 PRO A CB 1 ATOM 6596 C CG . PRO A 1 824 ? -64.748 0.820 -38.502 1.00 30.39 ? 824 PRO A CG 1 ATOM 6597 C CD . PRO A 1 824 ? -65.918 0.314 -37.727 1.00 29.25 ? 824 PRO A CD 1 ATOM 6598 N N . SER A 1 825 ? -67.805 1.571 -41.787 1.00 32.67 ? 825 SER A N 1 ATOM 6599 C CA . SER A 1 825 ? -68.430 0.936 -42.931 1.00 33.48 ? 825 SER A CA 1 ATOM 6600 C C . SER A 1 825 ? -67.802 1.576 -44.139 1.00 32.81 ? 825 SER A C 1 ATOM 6601 O O . SER A 1 825 ? -67.248 2.670 -44.016 1.00 32.07 ? 825 SER A O 1 ATOM 6602 C CB . SER A 1 825 ? -69.943 1.157 -42.906 1.00 33.39 ? 825 SER A CB 1 ATOM 6603 O OG . SER A 1 825 ? -70.256 2.506 -43.192 1.00 36.32 ? 825 SER A OG 1 ATOM 6604 N N . ASN A 1 826 ? -67.872 0.890 -45.283 1.00 32.77 ? 826 ASN A N 1 ATOM 6605 C CA . ASN A 1 826 ? -67.327 1.379 -46.559 1.00 33.36 ? 826 ASN A CA 1 ATOM 6606 C C . ASN A 1 826 ? -65.872 1.804 -46.457 1.00 32.26 ? 826 ASN A C 1 ATOM 6607 O O . ASN A 1 826 ? -65.541 2.919 -46.848 1.00 32.26 ? 826 ASN A O 1 ATOM 6608 C CB . ASN A 1 826 ? -68.111 2.588 -47.070 1.00 33.87 ? 826 ASN A CB 1 ATOM 6609 C CG . ASN A 1 826 ? -69.596 2.331 -47.158 1.00 38.72 ? 826 ASN A CG 1 ATOM 6610 O OD1 . ASN A 1 826 ? -70.047 1.176 -47.136 1.00 42.56 ? 826 ASN A OD1 1 ATOM 6611 N ND2 . ASN A 1 826 ? -70.375 3.414 -47.242 1.00 41.37 ? 826 ASN A ND2 1 ATOM 6612 N N . VAL A 1 827 ? -65.025 0.942 -45.912 1.00 31.24 ? 827 VAL A N 1 ATOM 6613 C CA . VAL A 1 827 ? -63.611 1.274 -45.747 1.00 30.15 ? 827 VAL A CA 1 ATOM 6614 C C . VAL A 1 827 ? -62.907 1.259 -47.096 1.00 29.63 ? 827 VAL A C 1 ATOM 6615 O O . VAL A 1 827 ? -62.960 0.284 -47.827 1.00 29.56 ? 827 VAL A O 1 ATOM 6616 C CB . VAL A 1 827 ? -62.931 0.361 -44.717 1.00 30.11 ? 827 VAL A CB 1 ATOM 6617 C CG1 . VAL A 1 827 ? -61.489 0.771 -44.530 1.00 30.10 ? 827 VAL A CG1 1 ATOM 6618 C CG2 . VAL A 1 827 ? -63.693 0.428 -43.396 1.00 30.29 ? 827 VAL A CG2 1 ATOM 6619 N N . THR A 1 828 ? -62.277 2.377 -47.422 1.00 29.73 ? 828 THR A N 1 ATOM 6620 C CA . THR A 1 828 ? -61.645 2.591 -48.708 1.00 30.44 ? 828 THR A CA 1 ATOM 6621 C C . THR A 1 828 ? -60.181 2.935 -48.482 1.00 29.85 ? 828 THR A C 1 ATOM 6622 O O . THR A 1 828 ? -59.846 3.633 -47.527 1.00 29.30 ? 828 THR A O 1 ATOM 6623 C CB . THR A 1 828 ? -62.305 3.779 -49.448 1.00 30.74 ? 828 THR A CB 1 ATOM 6624 O OG1 . THR A 1 828 ? -63.682 3.459 -49.715 1.00 34.32 ? 828 THR A OG1 1 ATOM 6625 C CG2 . THR A 1 828 ? -61.603 4.035 -50.786 1.00 33.30 ? 828 THR A CG2 1 ATOM 6626 N N . VAL A 1 829 ? -59.327 2.465 -49.376 1.00 29.21 ? 829 VAL A N 1 ATOM 6627 C CA . VAL A 1 829 ? -57.899 2.742 -49.268 1.00 29.73 ? 829 VAL A CA 1 ATOM 6628 C C . VAL A 1 829 ? -57.473 3.425 -50.548 1.00 30.31 ? 829 VAL A C 1 ATOM 6629 O O . VAL A 1 829 ? -57.756 2.919 -51.637 1.00 30.57 ? 829 VAL A O 1 ATOM 6630 C CB . VAL A 1 829 ? -57.097 1.453 -49.073 1.00 29.72 ? 829 VAL A CB 1 ATOM 6631 C CG1 . VAL A 1 829 ? -55.606 1.741 -49.087 1.00 28.38 ? 829 VAL A CG1 1 ATOM 6632 C CG2 . VAL A 1 829 ? -57.535 0.739 -47.814 1.00 28.49 ? 829 VAL A CG2 1 ATOM 6633 N N . LYS A 1 830 ? -56.842 4.587 -50.425 1.00 30.28 ? 830 LYS A N 1 ATOM 6634 C CA . LYS A 1 830 ? -56.307 5.301 -51.569 1.00 32.17 ? 830 LYS A CA 1 ATOM 6635 C C . LYS A 1 830 ? -54.790 5.375 -51.454 1.00 32.25 ? 830 LYS A C 1 ATOM 6636 O O . LYS A 1 830 ? -54.263 5.557 -50.369 1.00 30.27 ? 830 LYS A O 1 ATOM 6637 C CB . LYS A 1 830 ? -56.880 6.715 -51.657 1.00 32.01 ? 830 LYS A CB 1 ATOM 6638 C CG . LYS A 1 830 ? -58.381 6.765 -51.969 1.00 33.68 ? 830 LYS A CG 1 ATOM 6639 C CD . LYS A 1 830 ? -58.856 8.205 -52.207 1.00 35.02 ? 830 LYS A CD 1 ATOM 6640 C CE . LYS A 1 830 ? -60.355 8.228 -52.565 1.00 42.69 ? 830 LYS A CE 1 ATOM 6641 N NZ . LYS A 1 830 ? -60.814 9.566 -53.120 1.00 44.67 ? 830 LYS A NZ 1 ATOM 6642 N N . HIS A 1 831 ? -54.110 5.231 -52.582 1.00 34.30 ? 831 HIS A N 1 ATOM 6643 C CA . HIS A 1 831 ? -52.657 5.332 -52.645 1.00 36.80 ? 831 HIS A CA 1 ATOM 6644 C C . HIS A 1 831 ? -52.335 6.538 -53.494 1.00 38.96 ? 831 HIS A C 1 ATOM 6645 O O . HIS A 1 831 ? -52.786 6.620 -54.643 1.00 38.88 ? 831 HIS A O 1 ATOM 6646 C CB . HIS A 1 831 ? -52.046 4.036 -53.216 1.00 36.58 ? 831 HIS A CB 1 ATOM 6647 C CG . HIS A 1 831 ? -50.546 4.047 -53.330 1.00 36.77 ? 831 HIS A CG 1 ATOM 6648 N ND1 . HIS A 1 831 ? -49.860 3.164 -54.137 1.00 38.13 ? 831 HIS A ND1 1 ATOM 6649 C CD2 . HIS A 1 831 ? -49.601 4.828 -52.745 1.00 37.61 ? 831 HIS A CD2 1 ATOM 6650 C CE1 . HIS A 1 831 ? -48.560 3.402 -54.047 1.00 38.60 ? 831 HIS A CE1 1 ATOM 6651 N NE2 . HIS A 1 831 ? -48.376 4.406 -53.208 1.00 37.04 ? 831 HIS A NE2 1 ATOM 6652 N N . ASN A 1 832 ? -51.563 7.469 -52.918 1.00 41.44 ? 832 ASN A N 1 ATOM 6653 C CA . ASN A 1 832 ? -51.269 8.767 -53.532 1.00 44.15 ? 832 ASN A CA 1 ATOM 6654 C C . ASN A 1 832 ? -52.513 9.457 -54.087 1.00 45.50 ? 832 ASN A C 1 ATOM 6655 O O . ASN A 1 832 ? -52.431 10.155 -55.093 1.00 46.03 ? 832 ASN A O 1 ATOM 6656 C CB . ASN A 1 832 ? -50.224 8.625 -54.651 1.00 44.59 ? 832 ASN A CB 1 ATOM 6657 C CG . ASN A 1 832 ? -48.846 8.295 -54.126 1.00 46.54 ? 832 ASN A CG 1 ATOM 6658 O OD1 . ASN A 1 832 ? -48.332 8.974 -53.240 1.00 48.79 ? 832 ASN A OD1 1 ATOM 6659 N ND2 . ASN A 1 832 ? -48.236 7.243 -54.675 1.00 48.49 ? 832 ASN A ND2 1 ATOM 6660 N N . GLY A 1 833 ? -53.663 9.240 -53.448 1.00 46.89 ? 833 GLY A N 1 ATOM 6661 C CA . GLY A 1 833 ? -54.920 9.820 -53.911 1.00 48.49 ? 833 GLY A CA 1 ATOM 6662 C C . GLY A 1 833 ? -55.770 8.909 -54.773 1.00 49.89 ? 833 GLY A C 1 ATOM 6663 O O . GLY A 1 833 ? -56.927 9.224 -55.051 1.00 50.17 ? 833 GLY A O 1 ATOM 6664 N N . VAL A 1 834 ? -55.214 7.766 -55.167 1.00 51.02 ? 834 VAL A N 1 ATOM 6665 C CA . VAL A 1 834 ? -55.831 6.854 -56.130 1.00 52.20 ? 834 VAL A CA 1 ATOM 6666 C C . VAL A 1 834 ? -56.330 5.572 -55.450 1.00 53.48 ? 834 VAL A C 1 ATOM 6667 O O . VAL A 1 834 ? -55.539 4.850 -54.840 1.00 53.10 ? 834 VAL A O 1 ATOM 6668 C CB . VAL A 1 834 ? -54.801 6.461 -57.244 1.00 52.34 ? 834 VAL A CB 1 ATOM 6669 C CG1 . VAL A 1 834 ? -55.373 5.406 -58.214 1.00 51.88 ? 834 VAL A CG1 1 ATOM 6670 C CG2 . VAL A 1 834 ? -54.278 7.704 -57.989 1.00 51.90 ? 834 VAL A CG2 1 ATOM 6671 N N . PRO A 1 835 ? -57.645 5.281 -55.546 1.00 54.94 ? 835 PRO A N 1 ATOM 6672 C CA . PRO A 1 835 ? -58.090 3.940 -55.151 1.00 56.13 ? 835 PRO A CA 1 ATOM 6673 C C . PRO A 1 835 ? -57.850 3.035 -56.348 1.00 57.49 ? 835 PRO A C 1 ATOM 6674 O O . PRO A 1 835 ? -58.154 3.460 -57.465 1.00 58.45 ? 835 PRO A O 1 ATOM 6675 C CB . PRO A 1 835 ? -59.588 4.123 -54.899 1.00 56.26 ? 835 PRO A CB 1 ATOM 6676 C CG . PRO A 1 835 ? -59.996 5.320 -55.730 1.00 55.21 ? 835 PRO A CG 1 ATOM 6677 C CD . PRO A 1 835 ? -58.758 6.135 -56.017 1.00 55.18 ? 835 PRO A CD 1 ATOM 6678 N N . SER A 1 836 ? -57.339 1.811 -56.196 1.00 58.63 ? 836 SER A N 1 ATOM 6679 C CA . SER A 1 836 ? -57.225 1.034 -54.964 1.00 59.41 ? 836 SER A CA 1 ATOM 6680 C C . SER A 1 836 ? -58.573 0.766 -54.311 1.00 59.63 ? 836 SER A C 1 ATOM 6681 O O . SER A 1 836 ? -59.382 0.014 -54.864 1.00 59.65 ? 836 SER A O 1 ATOM 6682 C CB . SER A 1 836 ? -56.183 1.594 -53.992 1.00 59.65 ? 836 SER A CB 1 ATOM 6683 O OG . SER A 1 836 ? -55.847 0.610 -53.023 1.00 60.51 ? 836 SER A OG 1 ATOM 6684 N N . THR A 1 838 ? -59.593 -3.233 -54.333 1.00 45.16 ? 838 THR A N 1 ATOM 6685 C CA . THR A 1 838 ? -59.290 -3.583 -52.935 1.00 45.00 ? 838 THR A CA 1 ATOM 6686 C C . THR A 1 838 ? -60.355 -3.021 -51.987 1.00 43.49 ? 838 THR A C 1 ATOM 6687 O O . THR A 1 838 ? -60.577 -1.807 -51.951 1.00 44.56 ? 838 THR A O 1 ATOM 6688 C CB . THR A 1 838 ? -57.906 -3.054 -52.458 1.00 45.20 ? 838 THR A CB 1 ATOM 6689 O OG1 . THR A 1 838 ? -57.930 -1.618 -52.374 1.00 47.83 ? 838 THR A OG1 1 ATOM 6690 C CG2 . THR A 1 838 ? -56.771 -3.502 -53.385 1.00 46.94 ? 838 THR A CG2 1 ATOM 6691 N N . SER A 1 839 ? -61.036 -3.903 -51.265 1.00 41.27 ? 839 SER A N 1 ATOM 6692 C CA . SER A 1 839 ? -61.853 -3.512 -50.118 1.00 39.00 ? 839 SER A CA 1 ATOM 6693 C C . SER A 1 839 ? -61.314 -4.348 -48.969 1.00 36.08 ? 839 SER A C 1 ATOM 6694 O O . SER A 1 839 ? -61.353 -5.572 -49.050 1.00 36.99 ? 839 SER A O 1 ATOM 6695 C CB . SER A 1 839 ? -63.322 -3.830 -50.357 1.00 39.53 ? 839 SER A CB 1 ATOM 6696 O OG . SER A 1 839 ? -64.071 -3.650 -49.164 1.00 41.93 ? 839 SER A OG 1 ATOM 6697 N N . PRO A 1 840 ? -60.758 -3.704 -47.922 1.00 32.95 ? 840 PRO A N 1 ATOM 6698 C CA . PRO A 1 840 ? -60.172 -4.501 -46.848 1.00 29.95 ? 840 PRO A CA 1 ATOM 6699 C C . PRO A 1 840 ? -61.202 -5.244 -46.027 1.00 27.59 ? 840 PRO A C 1 ATOM 6700 O O . PRO A 1 840 ? -62.390 -4.940 -46.096 1.00 27.01 ? 840 PRO A O 1 ATOM 6701 C CB . PRO A 1 840 ? -59.491 -3.459 -45.974 1.00 29.97 ? 840 PRO A CB 1 ATOM 6702 C CG . PRO A 1 840 ? -60.247 -2.212 -46.229 1.00 32.35 ? 840 PRO A CG 1 ATOM 6703 C CD . PRO A 1 840 ? -60.577 -2.258 -47.681 1.00 32.73 ? 840 PRO A CD 1 ATOM 6704 N N . THR A 1 841 ? -60.740 -6.212 -45.243 1.00 24.50 ? 841 THR A N 1 ATOM 6705 C CA . THR A 1 841 ? -61.612 -6.907 -44.289 1.00 23.16 ? 841 THR A CA 1 ATOM 6706 C C . THR A 1 841 ? -61.719 -6.092 -43.007 1.00 22.48 ? 841 THR A C 1 ATOM 6707 O O . THR A 1 841 ? -60.707 -5.609 -42.493 1.00 20.43 ? 841 THR A O 1 ATOM 6708 C CB . THR A 1 841 ? -61.057 -8.332 -44.008 1.00 23.29 ? 841 THR A CB 1 ATOM 6709 O OG1 . THR A 1 841 ? -61.217 -9.138 -45.182 1.00 24.12 ? 841 THR A OG1 1 ATOM 6710 C CG2 . THR A 1 841 ? -61.739 -9.003 -42.829 1.00 22.50 ? 841 THR A CG2 1 ATOM 6711 N N . VAL A 1 842 ? -62.945 -5.899 -42.512 1.00 21.08 ? 842 VAL A N 1 ATOM 6712 C CA . VAL A 1 842 ? -63.158 -5.190 -41.251 1.00 21.43 ? 842 VAL A CA 1 ATOM 6713 C C . VAL A 1 842 ? -63.883 -6.092 -40.260 1.00 21.40 ? 842 VAL A C 1 ATOM 6714 O O . VAL A 1 842 ? -64.951 -6.661 -40.584 1.00 21.02 ? 842 VAL A O 1 ATOM 6715 C CB . VAL A 1 842 ? -64.007 -3.909 -41.455 1.00 22.39 ? 842 VAL A CB 1 ATOM 6716 C CG1 . VAL A 1 842 ? -64.231 -3.201 -40.104 1.00 22.31 ? 842 VAL A CG1 1 ATOM 6717 C CG2 . VAL A 1 842 ? -63.330 -3.005 -42.475 1.00 24.95 ? 842 VAL A CG2 1 ATOM 6718 N N . THR A 1 843 ? -63.280 -6.271 -39.082 1.00 19.95 ? 843 THR A N 1 ATOM 6719 C CA . THR A 1 843 ? -63.917 -6.975 -37.989 1.00 20.93 ? 843 THR A CA 1 ATOM 6720 C C . THR A 1 843 ? -64.299 -5.955 -36.918 1.00 20.46 ? 843 THR A C 1 ATOM 6721 O O . THR A 1 843 ? -63.515 -5.086 -36.583 1.00 20.51 ? 843 THR A O 1 ATOM 6722 C CB . THR A 1 843 ? -62.966 -7.991 -37.411 1.00 20.69 ? 843 THR A CB 1 ATOM 6723 O OG1 . THR A 1 843 ? -62.420 -8.785 -38.488 1.00 24.61 ? 843 THR A OG1 1 ATOM 6724 C CG2 . THR A 1 843 ? -63.621 -8.868 -36.378 1.00 22.22 ? 843 THR A CG2 1 ATOM 6725 N N . TYR A 1 844 ? -65.496 -6.074 -36.371 1.00 20.02 ? 844 TYR A N 1 ATOM 6726 C CA . TYR A 1 844 ? -65.912 -5.105 -35.397 1.00 19.52 ? 844 TYR A CA 1 ATOM 6727 C C . TYR A 1 844 ? -66.450 -5.767 -34.143 1.00 20.30 ? 844 TYR A C 1 ATOM 6728 O O . TYR A 1 844 ? -67.183 -6.760 -34.203 1.00 19.26 ? 844 TYR A O 1 ATOM 6729 C CB . TYR A 1 844 ? -66.918 -4.115 -36.019 1.00 19.44 ? 844 TYR A CB 1 ATOM 6730 C CG . TYR A 1 844 ? -67.265 -3.005 -35.070 1.00 18.94 ? 844 TYR A CG 1 ATOM 6731 C CD1 . TYR A 1 844 ? -66.291 -2.120 -34.636 1.00 16.50 ? 844 TYR A CD1 1 ATOM 6732 C CD2 . TYR A 1 844 ? -68.565 -2.875 -34.558 1.00 18.76 ? 844 TYR A CD2 1 ATOM 6733 C CE1 . TYR A 1 844 ? -66.577 -1.100 -33.719 1.00 18.00 ? 844 TYR A CE1 1 ATOM 6734 C CE2 . TYR A 1 844 ? -68.879 -1.872 -33.666 1.00 17.22 ? 844 TYR A CE2 1 ATOM 6735 C CZ . TYR A 1 844 ? -67.888 -0.980 -33.250 1.00 18.07 ? 844 TYR A CZ 1 ATOM 6736 O OH . TYR A 1 844 ? -68.200 0.015 -32.364 1.00 20.88 ? 844 TYR A OH 1 ATOM 6737 N N . ASP A 1 845 ? -66.055 -5.223 -32.996 1.00 20.40 ? 845 ASP A N 1 ATOM 6738 C CA . ASP A 1 845 ? -66.533 -5.647 -31.707 1.00 22.36 ? 845 ASP A CA 1 ATOM 6739 C C . ASP A 1 845 ? -67.392 -4.519 -31.149 1.00 23.15 ? 845 ASP A C 1 ATOM 6740 O O . ASP A 1 845 ? -66.865 -3.526 -30.666 1.00 22.70 ? 845 ASP A O 1 ATOM 6741 C CB . ASP A 1 845 ? -65.334 -5.881 -30.778 1.00 22.77 ? 845 ASP A CB 1 ATOM 6742 C CG . ASP A 1 845 ? -65.721 -6.547 -29.462 1.00 25.43 ? 845 ASP A CG 1 ATOM 6743 O OD1 . ASP A 1 845 ? -66.831 -6.325 -28.911 1.00 26.17 ? 845 ASP A OD1 1 ATOM 6744 O OD2 . ASP A 1 845 ? -64.897 -7.321 -28.963 1.00 27.08 ? 845 ASP A OD2 1 ATOM 6745 N N . SER A 1 846 ? -68.709 -4.679 -31.163 1.00 24.90 ? 846 SER A N 1 ATOM 6746 C CA . SER A 1 846 ? -69.584 -3.575 -30.756 1.00 26.51 ? 846 SER A CA 1 ATOM 6747 C C . SER A 1 846 ? -69.618 -3.342 -29.248 1.00 27.12 ? 846 SER A C 1 ATOM 6748 O O . SER A 1 846 ? -69.884 -2.229 -28.807 1.00 28.42 ? 846 SER A O 1 ATOM 6749 C CB . SER A 1 846 ? -71.000 -3.778 -31.307 1.00 26.87 ? 846 SER A CB 1 ATOM 6750 O OG . SER A 1 846 ? -71.488 -5.011 -30.844 1.00 28.76 ? 846 SER A OG 1 ATOM 6751 N N . ASN A 1 847 ? -69.333 -4.373 -28.468 1.00 27.38 ? 847 ASN A N 1 ATOM 6752 C CA . ASN A 1 847 ? -69.220 -4.274 -27.019 1.00 28.13 ? 847 ASN A CA 1 ATOM 6753 C C . ASN A 1 847 ? -67.965 -3.485 -26.596 1.00 27.02 ? 847 ASN A C 1 ATOM 6754 O O . ASN A 1 847 ? -68.037 -2.618 -25.734 1.00 27.16 ? 847 ASN A O 1 ATOM 6755 C CB . ASN A 1 847 ? -69.183 -5.681 -26.406 1.00 29.69 ? 847 ASN A CB 1 ATOM 6756 C CG . ASN A 1 847 ? -69.147 -5.668 -24.872 1.00 36.60 ? 847 ASN A CG 1 ATOM 6757 O OD1 . ASN A 1 847 ? -68.163 -6.127 -24.261 1.00 42.61 ? 847 ASN A OD1 1 ATOM 6758 N ND2 . ASN A 1 847 ? -70.221 -5.143 -24.234 1.00 39.65 ? 847 ASN A ND2 1 ATOM 6759 N N . LEU A 1 848 ? -66.827 -3.771 -27.220 1.00 25.07 ? 848 LEU A N 1 ATOM 6760 C CA . LEU A 1 848 ? -65.560 -3.115 -26.869 1.00 24.30 ? 848 LEU A CA 1 ATOM 6761 C C . LEU A 1 848 ? -65.295 -1.817 -27.647 1.00 22.00 ? 848 LEU A C 1 ATOM 6762 O O . LEU A 1 848 ? -64.369 -1.062 -27.311 1.00 20.91 ? 848 LEU A O 1 ATOM 6763 C CB . LEU A 1 848 ? -64.408 -4.122 -27.088 1.00 24.94 ? 848 LEU A CB 1 ATOM 6764 C CG . LEU A 1 848 ? -63.937 -4.904 -25.849 1.00 26.70 ? 848 LEU A CG 1 ATOM 6765 C CD1 . LEU A 1 848 ? -65.028 -5.215 -24.837 1.00 29.44 ? 848 LEU A CD1 1 ATOM 6766 C CD2 . LEU A 1 848 ? -63.162 -6.136 -26.217 1.00 27.48 ? 848 LEU A CD2 1 ATOM 6767 N N . LYS A 1 849 ? -66.082 -1.581 -28.702 1.00 19.41 ? 849 LYS A N 1 ATOM 6768 C CA . LYS A 1 849 ? -65.885 -0.480 -29.652 1.00 18.27 ? 849 LYS A CA 1 ATOM 6769 C C . LYS A 1 849 ? -64.477 -0.531 -30.313 1.00 18.36 ? 849 LYS A C 1 ATOM 6770 O O . LYS A 1 849 ? -63.803 0.472 -30.398 1.00 16.61 ? 849 LYS A O 1 ATOM 6771 C CB . LYS A 1 849 ? -66.139 0.885 -28.994 1.00 18.29 ? 849 LYS A CB 1 ATOM 6772 C CG . LYS A 1 849 ? -67.475 0.981 -28.223 1.00 20.58 ? 849 LYS A CG 1 ATOM 6773 C CD . LYS A 1 849 ? -68.608 1.000 -29.219 1.00 22.11 ? 849 LYS A CD 1 ATOM 6774 C CE . LYS A 1 849 ? -69.993 1.222 -28.556 1.00 25.69 ? 849 LYS A CE 1 ATOM 6775 N NZ . LYS A 1 849 ? -71.118 1.062 -29.573 1.00 28.46 ? 849 LYS A NZ 1 ATOM 6776 N N . VAL A 1 850 ? -64.106 -1.715 -30.779 1.00 17.82 ? 850 VAL A N 1 ATOM 6777 C CA . VAL A 1 850 ? -62.846 -1.962 -31.467 1.00 17.89 ? 850 VAL A CA 1 ATOM 6778 C C . VAL A 1 850 ? -63.108 -2.485 -32.873 1.00 17.25 ? 850 VAL A C 1 ATOM 6779 O O . VAL A 1 850 ? -63.883 -3.465 -33.059 1.00 17.94 ? 850 VAL A O 1 ATOM 6780 C CB . VAL A 1 850 ? -62.018 -3.012 -30.706 1.00 17.65 ? 850 VAL A CB 1 ATOM 6781 C CG1 . VAL A 1 850 ? -60.660 -3.295 -31.429 1.00 19.03 ? 850 VAL A CG1 1 ATOM 6782 C CG2 . VAL A 1 850 ? -61.797 -2.575 -29.252 1.00 17.40 ? 850 VAL A CG2 1 ATOM 6783 N N . ALA A 1 851 ? -62.437 -1.872 -33.851 1.00 16.74 ? 851 ALA A N 1 ATOM 6784 C CA . ALA A 1 851 ? -62.467 -2.323 -35.236 1.00 16.19 ? 851 ALA A CA 1 ATOM 6785 C C . ALA A 1 851 ? -61.055 -2.786 -35.576 1.00 18.02 ? 851 ALA A C 1 ATOM 6786 O O . ALA A 1 851 ? -60.095 -2.161 -35.132 1.00 15.29 ? 851 ALA A O 1 ATOM 6787 C CB . ALA A 1 851 ? -62.837 -1.199 -36.144 1.00 15.78 ? 851 ALA A CB 1 ATOM 6788 N N . ILE A 1 852 ? -60.950 -3.882 -36.320 1.00 17.65 ? 852 ILE A N 1 ATOM 6789 C CA . ILE A 1 852 ? -59.636 -4.258 -36.858 1.00 18.91 ? 852 ILE A CA 1 ATOM 6790 C C . ILE A 1 852 ? -59.771 -4.370 -38.352 1.00 18.84 ? 852 ILE A C 1 ATOM 6791 O O . ILE A 1 852 ? -60.633 -5.099 -38.849 1.00 19.04 ? 852 ILE A O 1 ATOM 6792 C CB . ILE A 1 852 ? -59.103 -5.564 -36.301 1.00 19.25 ? 852 ILE A CB 1 ATOM 6793 C CG1 . ILE A 1 852 ? -59.070 -5.533 -34.776 1.00 21.22 ? 852 ILE A CG1 1 ATOM 6794 C CG2 . ILE A 1 852 ? -57.638 -5.814 -36.865 1.00 19.38 ? 852 ILE A CG2 1 ATOM 6795 C CD1 . ILE A 1 852 ? -58.824 -6.902 -34.165 1.00 25.77 ? 852 ILE A CD1 1 ATOM 6796 N N . ILE A 1 853 ? -58.901 -3.669 -39.066 1.00 18.81 ? 853 ILE A N 1 ATOM 6797 C CA . ILE A 1 853 ? -58.931 -3.674 -40.513 1.00 19.67 ? 853 ILE A CA 1 ATOM 6798 C C . ILE A 1 853 ? -57.799 -4.574 -40.934 1.00 21.36 ? 853 ILE A C 1 ATOM 6799 O O . ILE A 1 853 ? -56.638 -4.404 -40.512 1.00 19.32 ? 853 ILE A O 1 ATOM 6800 C CB . ILE A 1 853 ? -58.735 -2.271 -41.123 1.00 20.21 ? 853 ILE A CB 1 ATOM 6801 C CG1 . ILE A 1 853 ? -59.812 -1.298 -40.608 1.00 21.29 ? 853 ILE A CG1 1 ATOM 6802 C CG2 . ILE A 1 853 ? -58.734 -2.332 -42.652 1.00 20.39 ? 853 ILE A CG2 1 ATOM 6803 C CD1 . ILE A 1 853 ? -59.533 0.147 -40.961 1.00 24.33 ? 853 ILE A CD1 1 ATOM 6804 N N . THR A 1 854 ? -58.128 -5.510 -41.802 1.00 20.87 ? 854 THR A N 1 ATOM 6805 C CA . THR A 1 854 ? -57.150 -6.488 -42.218 1.00 23.55 ? 854 THR A CA 1 ATOM 6806 C C . THR A 1 854 ? -57.314 -6.710 -43.737 1.00 23.64 ? 854 THR A C 1 ATOM 6807 O O . THR A 1 854 ? -58.134 -6.029 -44.374 1.00 21.89 ? 854 THR A O 1 ATOM 6808 C CB . THR A 1 854 ? -57.351 -7.722 -41.320 1.00 23.37 ? 854 THR A CB 1 ATOM 6809 O OG1 . THR A 1 854 ? -56.151 -8.482 -41.247 1.00 31.26 ? 854 THR A OG1 1 ATOM 6810 C CG2 . THR A 1 854 ? -58.514 -8.540 -41.757 1.00 18.40 ? 854 THR A CG2 1 ATOM 6811 N N . ASP A 1 855 ? -56.520 -7.625 -44.307 1.00 24.93 ? 855 ASP A N 1 ATOM 6812 C CA . ASP A 1 855 ? -56.470 -7.843 -45.753 1.00 26.77 ? 855 ASP A CA 1 ATOM 6813 C C . ASP A 1 855 ? -56.098 -6.512 -46.436 1.00 26.68 ? 855 ASP A C 1 ATOM 6814 O O . ASP A 1 855 ? -56.749 -6.029 -47.375 1.00 25.82 ? 855 ASP A O 1 ATOM 6815 C CB . ASP A 1 855 ? -57.794 -8.434 -46.251 1.00 26.44 ? 855 ASP A CB 1 ATOM 6816 C CG . ASP A 1 855 ? -57.712 -8.950 -47.680 1.00 31.45 ? 855 ASP A CG 1 ATOM 6817 O OD1 . ASP A 1 855 ? -56.586 -9.318 -48.117 1.00 34.38 ? 855 ASP A OD1 1 ATOM 6818 O OD2 . ASP A 1 855 ? -58.783 -8.975 -48.364 1.00 33.47 ? 855 ASP A OD2 1 ATOM 6819 N N . ILE A 1 856 ? -55.037 -5.909 -45.908 1.00 26.45 ? 856 ILE A N 1 ATOM 6820 C CA . ILE A 1 856 ? -54.617 -4.614 -46.351 1.00 27.36 ? 856 ILE A CA 1 ATOM 6821 C C . ILE A 1 856 ? -53.108 -4.730 -46.467 1.00 26.40 ? 856 ILE A C 1 ATOM 6822 O O . ILE A 1 856 ? -52.503 -5.564 -45.803 1.00 25.85 ? 856 ILE A O 1 ATOM 6823 C CB . ILE A 1 856 ? -55.156 -3.498 -45.358 1.00 27.31 ? 856 ILE A CB 1 ATOM 6824 C CG1 . ILE A 1 856 ? -55.143 -2.113 -45.976 1.00 29.15 ? 856 ILE A CG1 1 ATOM 6825 C CG2 . ILE A 1 856 ? -54.423 -3.501 -44.017 1.00 28.64 ? 856 ILE A CG2 1 ATOM 6826 C CD1 . ILE A 1 856 ? -55.645 -0.990 -45.005 1.00 30.67 ? 856 ILE A CD1 1 ATOM 6827 N N . ASP A 1 857 ? -52.515 -3.936 -47.337 1.00 26.40 ? 857 ASP A N 1 ATOM 6828 C CA . ASP A 1 857 ? -51.073 -3.991 -47.531 1.00 27.81 ? 857 ASP A CA 1 ATOM 6829 C C . ASP A 1 857 ? -50.583 -2.580 -47.824 1.00 26.29 ? 857 ASP A C 1 ATOM 6830 O O . ASP A 1 857 ? -50.443 -2.203 -48.982 1.00 27.86 ? 857 ASP A O 1 ATOM 6831 C CB . ASP A 1 857 ? -50.793 -4.946 -48.695 1.00 28.93 ? 857 ASP A CB 1 ATOM 6832 C CG . ASP A 1 857 ? -49.341 -5.160 -48.936 1.00 34.06 ? 857 ASP A CG 1 ATOM 6833 O OD1 . ASP A 1 857 ? -48.623 -5.604 -48.007 1.00 39.38 ? 857 ASP A OD1 1 ATOM 6834 O OD2 . ASP A 1 857 ? -48.920 -4.896 -50.077 1.00 41.75 ? 857 ASP A OD2 1 ATOM 6835 N N . LEU A 1 858 ? -50.339 -1.778 -46.781 1.00 24.37 ? 858 LEU A N 1 ATOM 6836 C CA . LEU A 1 858 ? -49.911 -0.405 -46.966 1.00 22.05 ? 858 LEU A CA 1 ATOM 6837 C C . LEU A 1 858 ? -48.414 -0.358 -46.877 1.00 22.62 ? 858 LEU A C 1 ATOM 6838 O O . LEU A 1 858 ? -47.853 -0.444 -45.785 1.00 22.11 ? 858 LEU A O 1 ATOM 6839 C CB . LEU A 1 858 ? -50.508 0.502 -45.896 1.00 22.73 ? 858 LEU A CB 1 ATOM 6840 C CG . LEU A 1 858 ? -52.017 0.405 -45.580 1.00 22.44 ? 858 LEU A CG 1 ATOM 6841 C CD1 . LEU A 1 858 ? -52.371 1.512 -44.638 1.00 23.27 ? 858 LEU A CD1 1 ATOM 6842 C CD2 . LEU A 1 858 ? -52.833 0.527 -46.857 1.00 23.54 ? 858 LEU A CD2 1 ATOM 6843 N N . LEU A 1 859 ? -47.752 -0.247 -48.017 1.00 21.36 ? 859 LEU A N 1 ATOM 6844 C CA . LEU A 1 859 ? -46.304 -0.392 -48.022 1.00 21.41 ? 859 LEU A CA 1 ATOM 6845 C C . LEU A 1 859 ? -45.645 0.704 -47.196 1.00 21.62 ? 859 LEU A C 1 ATOM 6846 O O . LEU A 1 859 ? -45.951 1.886 -47.326 1.00 20.25 ? 859 LEU A O 1 ATOM 6847 C CB . LEU A 1 859 ? -45.768 -0.371 -49.452 1.00 20.80 ? 859 LEU A CB 1 ATOM 6848 C CG . LEU A 1 859 ? -46.365 -1.430 -50.404 1.00 22.53 ? 859 LEU A CG 1 ATOM 6849 C CD1 . LEU A 1 859 ? -45.980 -1.096 -51.843 1.00 25.29 ? 859 LEU A CD1 1 ATOM 6850 C CD2 . LEU A 1 859 ? -45.965 -2.874 -50.040 1.00 24.53 ? 859 LEU A CD2 1 ATOM 6851 N N . LEU A 1 860 ? -44.738 0.289 -46.328 1.00 22.27 ? 860 LEU A N 1 ATOM 6852 C CA . LEU A 1 860 ? -43.929 1.229 -45.582 1.00 23.51 ? 860 LEU A CA 1 ATOM 6853 C C . LEU A 1 860 ? -43.200 2.184 -46.533 1.00 23.87 ? 860 LEU A C 1 ATOM 6854 O O . LEU A 1 860 ? -42.572 1.756 -47.514 1.00 25.32 ? 860 LEU A O 1 ATOM 6855 C CB . LEU A 1 860 ? -42.922 0.443 -44.721 1.00 23.54 ? 860 LEU A CB 1 ATOM 6856 C CG . LEU A 1 860 ? -42.208 1.216 -43.631 1.00 24.57 ? 860 LEU A CG 1 ATOM 6857 C CD1 . LEU A 1 860 ? -43.158 1.717 -42.574 1.00 25.80 ? 860 LEU A CD1 1 ATOM 6858 C CD2 . LEU A 1 860 ? -41.138 0.330 -43.035 1.00 27.60 ? 860 LEU A CD2 1 ATOM 6859 N N . GLY A 1 861 ? -43.323 3.471 -46.286 1.00 22.55 ? 861 GLY A N 1 ATOM 6860 C CA . GLY A 1 861 ? -42.684 4.432 -47.156 1.00 23.11 ? 861 GLY A CA 1 ATOM 6861 C C . GLY A 1 861 ? -43.578 5.019 -48.224 1.00 23.62 ? 861 GLY A C 1 ATOM 6862 O O . GLY A 1 861 ? -43.138 5.849 -48.989 1.00 25.24 ? 861 GLY A O 1 ATOM 6863 N N . GLU A 1 862 ? -44.845 4.620 -48.268 1.00 22.17 ? 862 GLU A N 1 ATOM 6864 C CA . GLU A 1 862 ? -45.763 5.122 -49.286 1.00 21.83 ? 862 GLU A CA 1 ATOM 6865 C C . GLU A 1 862 ? -46.889 5.863 -48.575 1.00 21.47 ? 862 GLU A C 1 ATOM 6866 O O . GLU A 1 862 ? -47.254 5.502 -47.469 1.00 20.45 ? 862 GLU A O 1 ATOM 6867 C CB . GLU A 1 862 ? -46.394 3.962 -50.094 1.00 22.87 ? 862 GLU A CB 1 ATOM 6868 C CG . GLU A 1 862 ? -45.510 3.253 -51.112 1.00 24.33 ? 862 GLU A CG 1 ATOM 6869 C CD . GLU A 1 862 ? -44.955 4.220 -52.126 1.00 30.74 ? 862 GLU A CD 1 ATOM 6870 O OE1 . GLU A 1 862 ? -45.748 4.885 -52.838 1.00 32.32 ? 862 GLU A OE1 1 ATOM 6871 O OE2 . GLU A 1 862 ? -43.712 4.334 -52.206 1.00 31.37 ? 862 GLU A OE2 1 ATOM 6872 N N . ALA A 1 863 ? -47.459 6.852 -49.249 1.00 20.80 ? 863 ALA A N 1 ATOM 6873 C CA . ALA A 1 863 ? -48.542 7.668 -48.702 1.00 20.89 ? 863 ALA A CA 1 ATOM 6874 C C . ALA A 1 863 ? -49.883 7.036 -49.018 1.00 21.56 ? 863 ALA A C 1 ATOM 6875 O O . ALA A 1 863 ? -50.109 6.575 -50.150 1.00 21.47 ? 863 ALA A O 1 ATOM 6876 C CB . ALA A 1 863 ? -48.497 9.031 -49.316 1.00 20.89 ? 863 ALA A CB 1 ATOM 6877 N N . TYR A 1 864 ? -50.773 7.031 -48.028 1.00 21.14 ? 864 TYR A N 1 ATOM 6878 C CA . TYR A 1 864 ? -52.061 6.375 -48.166 1.00 21.53 ? 864 TYR A CA 1 ATOM 6879 C C . TYR A 1 864 ? -53.089 7.207 -47.432 1.00 22.11 ? 864 TYR A C 1 ATOM 6880 O O . TYR A 1 864 ? -52.745 7.947 -46.516 1.00 20.83 ? 864 TYR A O 1 ATOM 6881 C CB . TYR A 1 864 ? -52.072 4.974 -47.538 1.00 20.41 ? 864 TYR A CB 1 ATOM 6882 C CG . TYR A 1 864 ? -51.267 3.964 -48.275 1.00 20.29 ? 864 TYR A CG 1 ATOM 6883 C CD1 . TYR A 1 864 ? -51.777 3.310 -49.401 1.00 18.27 ? 864 TYR A CD1 1 ATOM 6884 C CD2 . TYR A 1 864 ? -49.956 3.667 -47.856 1.00 19.59 ? 864 TYR A CD2 1 ATOM 6885 C CE1 . TYR A 1 864 ? -51.015 2.372 -50.083 1.00 20.19 ? 864 TYR A CE1 1 ATOM 6886 C CE2 . TYR A 1 864 ? -49.186 2.754 -48.552 1.00 16.62 ? 864 TYR A CE2 1 ATOM 6887 C CZ . TYR A 1 864 ? -49.698 2.115 -49.640 1.00 19.55 ? 864 TYR A CZ 1 ATOM 6888 O OH . TYR A 1 864 ? -48.910 1.196 -50.281 1.00 20.80 ? 864 TYR A OH 1 ATOM 6889 N N . THR A 1 865 ? -54.348 7.072 -47.852 1.00 23.92 ? 865 THR A N 1 ATOM 6890 C CA . THR A 1 865 ? -55.481 7.551 -47.090 1.00 26.43 ? 865 THR A CA 1 ATOM 6891 C C . THR A 1 865 ? -56.402 6.342 -46.870 1.00 26.50 ? 865 THR A C 1 ATOM 6892 O O . THR A 1 865 ? -56.625 5.576 -47.781 1.00 28.19 ? 865 THR A O 1 ATOM 6893 C CB . THR A 1 865 ? -56.203 8.696 -47.853 1.00 26.72 ? 865 THR A CB 1 ATOM 6894 O OG1 . THR A 1 865 ? -55.256 9.753 -48.124 1.00 30.01 ? 865 THR A OG1 1 ATOM 6895 C CG2 . THR A 1 865 ? -57.313 9.274 -47.008 1.00 29.11 ? 865 THR A CG2 1 ATOM 6896 N N . VAL A 1 866 ? -56.873 6.113 -45.651 1.00 26.58 ? 866 VAL A N 1 ATOM 6897 C CA . VAL A 1 866 ? -57.862 5.065 -45.433 1.00 26.07 ? 866 VAL A CA 1 ATOM 6898 C C . VAL A 1 866 ? -59.063 5.823 -44.902 1.00 26.75 ? 866 VAL A C 1 ATOM 6899 O O . VAL A 1 866 ? -58.930 6.579 -43.944 1.00 26.09 ? 866 VAL A O 1 ATOM 6900 C CB . VAL A 1 866 ? -57.387 3.981 -44.442 1.00 25.59 ? 866 VAL A CB 1 ATOM 6901 C CG1 . VAL A 1 866 ? -58.429 2.884 -44.262 1.00 26.33 ? 866 VAL A CG1 1 ATOM 6902 C CG2 . VAL A 1 866 ? -56.027 3.375 -44.903 1.00 24.86 ? 866 VAL A CG2 1 ATOM 6903 N N . GLU A 1 867 ? -60.221 5.636 -45.534 1.00 27.45 ? 867 GLU A N 1 ATOM 6904 C CA . GLU A 1 867 ? -61.411 6.408 -45.182 1.00 29.73 ? 867 GLU A CA 1 ATOM 6905 C C . GLU A 1 867 ? -62.545 5.467 -44.869 1.00 28.53 ? 867 GLU A C 1 ATOM 6906 O O . GLU A 1 867 ? -62.620 4.392 -45.430 1.00 27.98 ? 867 GLU A O 1 ATOM 6907 C CB . GLU A 1 867 ? -61.820 7.321 -46.343 1.00 29.38 ? 867 GLU A CB 1 ATOM 6908 C CG . GLU A 1 867 ? -60.869 8.508 -46.575 1.00 33.99 ? 867 GLU A CG 1 ATOM 6909 C CD . GLU A 1 867 ? -61.301 9.404 -47.742 1.00 34.60 ? 867 GLU A CD 1 ATOM 6910 O OE1 . GLU A 1 867 ? -61.065 9.018 -48.918 1.00 38.21 ? 867 GLU A OE1 1 ATOM 6911 O OE2 . GLU A 1 867 ? -61.861 10.499 -47.460 1.00 41.05 ? 867 GLU A OE2 1 ATOM 6912 N N . TRP A 1 868 ? -63.419 5.868 -43.958 1.00 29.54 ? 868 TRP A N 1 ATOM 6913 C CA . TRP A 1 868 ? -64.591 5.071 -43.653 1.00 30.62 ? 868 TRP A CA 1 ATOM 6914 C C . TRP A 1 868 ? -65.777 5.956 -43.320 1.00 31.82 ? 868 TRP A C 1 ATOM 6915 O O . TRP A 1 868 ? -65.634 7.155 -43.071 1.00 31.04 ? 868 TRP A O 1 ATOM 6916 C CB . TRP A 1 868 ? -64.313 4.091 -42.503 1.00 29.68 ? 868 TRP A CB 1 ATOM 6917 C CG . TRP A 1 868 ? -63.873 4.722 -41.236 1.00 29.79 ? 868 TRP A CG 1 ATOM 6918 C CD1 . TRP A 1 868 ? -64.663 5.099 -40.191 1.00 29.61 ? 868 TRP A CD1 1 ATOM 6919 C CD2 . TRP A 1 868 ? -62.529 5.051 -40.867 1.00 29.53 ? 868 TRP A CD2 1 ATOM 6920 N NE1 . TRP A 1 868 ? -63.895 5.641 -39.183 1.00 28.41 ? 868 TRP A NE1 1 ATOM 6921 C CE2 . TRP A 1 868 ? -62.580 5.631 -39.583 1.00 30.06 ? 868 TRP A CE2 1 ATOM 6922 C CE3 . TRP A 1 868 ? -61.282 4.896 -41.497 1.00 29.02 ? 868 TRP A CE3 1 ATOM 6923 C CZ2 . TRP A 1 868 ? -61.430 6.057 -38.905 1.00 30.18 ? 868 TRP A CZ2 1 ATOM 6924 C CZ3 . TRP A 1 868 ? -60.137 5.327 -40.827 1.00 27.28 ? 868 TRP A CZ3 1 ATOM 6925 C CH2 . TRP A 1 868 ? -60.223 5.905 -39.544 1.00 28.58 ? 868 TRP A CH2 1 ATOM 6926 N N . ALA A 1 869 ? -66.952 5.349 -43.320 1.00 33.97 ? 869 ALA A N 1 ATOM 6927 C CA . ALA A 1 869 ? -68.168 6.023 -42.902 1.00 35.91 ? 869 ALA A CA 1 ATOM 6928 C C . ALA A 1 869 ? -68.639 5.330 -41.629 1.00 37.88 ? 869 ALA A C 1 ATOM 6929 O O . ALA A 1 869 ? -68.021 4.356 -41.172 1.00 37.11 ? 869 ALA A O 1 ATOM 6930 C CB . ALA A 1 869 ? -69.205 5.920 -43.981 1.00 36.14 ? 869 ALA A CB 1 ATOM 6931 N N . HIS A 1 870 ? -69.710 5.852 -41.040 1.00 39.74 ? 870 HIS A N 1 ATOM 6932 C CA . HIS A 1 870 ? -70.301 5.238 -39.862 1.00 41.81 ? 870 HIS A CA 1 ATOM 6933 C C . HIS A 1 870 ? -71.758 4.837 -40.115 1.00 42.68 ? 870 HIS A C 1 ATOM 6934 O O . HIS A 1 870 ? -72.667 5.655 -39.984 1.00 44.15 ? 870 HIS A O 1 ATOM 6935 C CB . HIS A 1 870 ? -70.178 6.173 -38.666 1.00 42.39 ? 870 HIS A CB 1 ATOM 6936 C CG . HIS A 1 870 ? -68.778 6.315 -38.162 1.00 44.13 ? 870 HIS A CG 1 ATOM 6937 N ND1 . HIS A 1 870 ? -68.124 5.301 -37.493 1.00 45.72 ? 870 HIS A ND1 1 ATOM 6938 C CD2 . HIS A 1 870 ? -67.904 7.348 -38.225 1.00 45.96 ? 870 HIS A CD2 1 ATOM 6939 C CE1 . HIS A 1 870 ? -66.910 5.706 -37.163 1.00 46.14 ? 870 HIS A CE1 1 ATOM 6940 N NE2 . HIS A 1 870 ? -66.751 6.944 -37.595 1.00 46.01 ? 870 HIS A NE2 1 HETATM 6941 C C1A . ACR B 2 . ? -19.671 -5.990 -10.611 1.00 27.17 ? 1001 ACR A C1A 1 HETATM 6942 C C2A . ACR B 2 . ? -20.730 -5.683 -11.690 1.00 24.26 ? 1001 ACR A C2A 1 HETATM 6943 C C3A . ACR B 2 . ? -21.560 -6.936 -11.971 1.00 23.98 ? 1001 ACR A C3A 1 HETATM 6944 C C4A . ACR B 2 . ? -20.667 -7.964 -12.639 1.00 21.49 ? 1001 ACR A C4A 1 HETATM 6945 C C5A . ACR B 2 . ? -19.347 -8.105 -11.911 1.00 22.16 ? 1001 ACR A C5A 1 HETATM 6946 C C6A . ACR B 2 . ? -18.589 -9.368 -12.180 1.00 23.23 ? 1001 ACR A C6A 1 HETATM 6947 C C7A . ACR B 2 . ? -18.833 -7.168 -11.099 1.00 22.16 ? 1001 ACR A C7A 1 HETATM 6948 O O2A . ACR B 2 . ? -21.598 -4.643 -11.261 1.00 25.02 ? 1001 ACR A O2A 1 HETATM 6949 O O3A . ACR B 2 . ? -22.795 -6.725 -12.743 1.00 18.66 ? 1001 ACR A O3A 1 HETATM 6950 O O4A . ACR B 2 . ? -21.341 -9.222 -12.655 1.00 24.78 ? 1001 ACR A O4A 1 HETATM 6951 O O6A . ACR B 2 . ? -17.857 -9.052 -13.380 1.00 26.24 ? 1001 ACR A O6A 1 HETATM 6952 C C1B . ACR B 2 . ? -18.217 -6.743 -5.386 1.00 30.43 ? 1001 ACR A C1B 1 HETATM 6953 C C2B . ACR B 2 . ? -17.840 -5.556 -6.271 1.00 30.34 ? 1001 ACR A C2B 1 HETATM 6954 C C3B . ACR B 2 . ? -18.974 -5.248 -7.262 1.00 27.16 ? 1001 ACR A C3B 1 HETATM 6955 C C4B . ACR B 2 . ? -19.240 -6.467 -8.146 1.00 27.94 ? 1001 ACR A C4B 1 HETATM 6956 C C5B . ACR B 2 . ? -19.594 -7.651 -7.221 1.00 28.48 ? 1001 ACR A C5B 1 HETATM 6957 C C6B . ACR B 2 . ? -19.763 -8.957 -7.990 1.00 28.96 ? 1001 ACR A C6B 1 HETATM 6958 N N4B . ACR B 2 . ? -20.200 -6.177 -9.233 1.00 28.16 ? 1001 ACR A N4B 1 HETATM 6959 O O2B . ACR B 2 . ? -17.624 -4.418 -5.439 1.00 28.67 ? 1001 ACR A O2B 1 HETATM 6960 O O3B . ACR B 2 . ? -18.618 -4.157 -8.104 1.00 27.80 ? 1001 ACR A O3B 1 HETATM 6961 O O5B . ACR B 2 . ? -18.541 -7.843 -6.242 1.00 27.94 ? 1001 ACR A O5B 1 HETATM 6962 C C1C . ACR B 2 . ? -21.057 -7.738 -0.958 1.00 48.71 ? 1001 ACR A C1C 1 HETATM 6963 C C2C . ACR B 2 . ? -19.534 -7.739 -1.040 1.00 46.42 ? 1001 ACR A C2C 1 HETATM 6964 C C3C . ACR B 2 . ? -19.020 -6.961 -2.255 1.00 44.64 ? 1001 ACR A C3C 1 HETATM 6965 C C4C . ACR B 2 . ? -19.722 -7.338 -3.560 1.00 42.22 ? 1001 ACR A C4C 1 HETATM 6966 C C5C . ACR B 2 . ? -21.242 -7.338 -3.363 1.00 45.44 ? 1001 ACR A C5C 1 HETATM 6967 C C6C . ACR B 2 . ? -21.995 -7.854 -4.585 1.00 46.16 ? 1001 ACR A C6C 1 HETATM 6968 O O2C . ACR B 2 . ? -19.040 -7.061 0.109 1.00 49.06 ? 1001 ACR A O2C 1 HETATM 6969 O O3C . ACR B 2 . ? -17.604 -7.128 -2.405 1.00 44.16 ? 1001 ACR A O3C 1 HETATM 6970 O O4C . ACR B 2 . ? -19.345 -6.391 -4.560 1.00 36.71 ? 1001 ACR A O4C 1 HETATM 6971 O O5C . ACR B 2 . ? -21.593 -8.154 -2.226 1.00 48.08 ? 1001 ACR A O5C 1 HETATM 6972 O O6C . ACR B 2 . ? -23.397 -7.936 -4.288 1.00 47.81 ? 1001 ACR A O6C 1 HETATM 6973 C C1D . ACR B 2 . ? -24.436 -4.540 1.835 1.00 58.11 ? 1001 ACR A C1D 1 HETATM 6974 C C2D . ACR B 2 . ? -22.960 -4.623 2.306 1.00 58.20 ? 1001 ACR A C2D 1 HETATM 6975 C C3D . ACR B 2 . ? -21.993 -5.060 1.199 1.00 57.23 ? 1001 ACR A C3D 1 HETATM 6976 C C4D . ACR B 2 . ? -22.487 -6.269 0.398 1.00 54.84 ? 1001 ACR A C4D 1 HETATM 6977 C C5D . ACR B 2 . ? -23.907 -5.941 -0.121 1.00 55.11 ? 1001 ACR A C5D 1 HETATM 6978 C C6D . ACR B 2 . ? -24.541 -7.046 -0.971 1.00 54.21 ? 1001 ACR A C6D 1 HETATM 6979 O O1D . ACR B 2 . ? -24.725 -3.278 1.208 1.00 59.32 ? 1001 ACR A O1D 1 HETATM 6980 O O2D . ACR B 2 . ? -22.490 -3.360 2.819 1.00 59.17 ? 1001 ACR A O2D 1 HETATM 6981 O O3D . ACR B 2 . ? -20.679 -5.312 1.738 1.00 58.19 ? 1001 ACR A O3D 1 HETATM 6982 O O4D . ACR B 2 . ? -21.517 -6.416 -0.648 1.00 51.12 ? 1001 ACR A O4D 1 HETATM 6983 O O5D . ACR B 2 . ? -24.819 -5.618 0.955 1.00 55.98 ? 1001 ACR A O5D 1 HETATM 6984 O O6D . ACR B 2 . ? -25.849 -6.622 -1.396 1.00 52.98 ? 1001 ACR A O6D 1 HETATM 6985 C C1 A NAG C 3 . ? -39.030 -15.899 -36.871 0.50 21.69 ? 2001 NAG A C1 1 HETATM 6986 C C1 B NAG C 3 . ? -39.076 -16.719 -34.686 0.50 26.71 ? 2001 NAG A C1 1 HETATM 6987 C C2 A NAG C 3 . ? -39.647 -16.019 -38.264 0.50 21.78 ? 2001 NAG A C2 1 HETATM 6988 C C2 B NAG C 3 . ? -39.606 -18.100 -34.291 0.50 28.21 ? 2001 NAG A C2 1 HETATM 6989 C C3 A NAG C 3 . ? -39.279 -17.396 -38.876 0.50 23.80 ? 2001 NAG A C3 1 HETATM 6990 C C3 B NAG C 3 . ? -38.572 -19.112 -34.713 0.50 29.28 ? 2001 NAG A C3 1 HETATM 6991 C C4 A NAG C 3 . ? -37.776 -17.702 -38.786 0.50 23.65 ? 2001 NAG A C4 1 HETATM 6992 C C4 B NAG C 3 . ? -38.635 -19.131 -36.229 0.50 29.79 ? 2001 NAG A C4 1 HETATM 6993 C C5 A NAG C 3 . ? -37.242 -17.411 -37.385 0.50 24.41 ? 2001 NAG A C5 1 HETATM 6994 C C5 B NAG C 3 . ? -38.344 -17.755 -36.819 0.50 29.08 ? 2001 NAG A C5 1 HETATM 6995 C C6 A NAG C 3 . ? -35.724 -17.590 -37.322 0.50 24.33 ? 2001 NAG A C6 1 HETATM 6996 C C6 B NAG C 3 . ? -38.929 -17.747 -38.228 0.50 27.90 ? 2001 NAG A C6 1 HETATM 6997 C C7 A NAG C 3 . ? -41.978 -14.972 -38.131 0.50 24.99 ? 2001 NAG A C7 1 HETATM 6998 C C7 B NAG C 3 . ? -41.139 -18.242 -32.372 0.50 27.94 ? 2001 NAG A C7 1 HETATM 6999 C C8 A NAG C 3 . ? -42.334 -14.416 -36.771 0.50 25.31 ? 2001 NAG A C8 1 HETATM 7000 C C8 B NAG C 3 . ? -41.988 -17.066 -32.764 0.50 26.29 ? 2001 NAG A C8 1 HETATM 7001 N N2 A NAG C 3 . ? -41.096 -15.983 -38.173 0.50 23.26 ? 2001 NAG A N2 1 HETATM 7002 N N2 B NAG C 3 . ? -39.906 -18.268 -32.879 0.50 25.46 ? 2001 NAG A N2 1 HETATM 7003 O O3 A NAG C 3 . ? -39.712 -17.501 -40.225 0.50 20.87 ? 2001 NAG A O3 1 HETATM 7004 O O3 B NAG C 3 . ? -38.959 -20.361 -34.220 0.50 31.87 ? 2001 NAG A O3 1 HETATM 7005 O O4 A NAG C 3 . ? -37.500 -19.050 -39.103 0.50 27.00 ? 2001 NAG A O4 1 HETATM 7006 O O4 B NAG C 3 . ? -37.755 -20.099 -36.767 0.50 31.44 ? 2001 NAG A O4 1 HETATM 7007 O O5 A NAG C 3 . ? -37.625 -16.094 -37.016 0.50 23.26 ? 2001 NAG A O5 1 HETATM 7008 O O5 B NAG C 3 . ? -38.894 -16.644 -36.099 0.50 25.89 ? 2001 NAG A O5 1 HETATM 7009 O O6 A NAG C 3 . ? -35.379 -17.914 -35.994 0.50 27.89 ? 2001 NAG A O6 1 HETATM 7010 O O6 B NAG C 3 . ? -37.888 -17.641 -39.175 0.50 26.69 ? 2001 NAG A O6 1 HETATM 7011 O O7 A NAG C 3 . ? -42.561 -14.567 -39.143 0.50 26.25 ? 2001 NAG A O7 1 HETATM 7012 O O7 B NAG C 3 . ? -41.576 -19.113 -31.604 0.50 25.94 ? 2001 NAG A O7 1 HETATM 7013 C C1 . NAG D 3 . ? -26.869 0.395 4.878 1.00 42.52 ? 2005 NAG A C1 1 HETATM 7014 C C2 . NAG D 3 . ? -27.828 -0.785 4.663 1.00 45.29 ? 2005 NAG A C2 1 HETATM 7015 C C3 . NAG D 3 . ? -27.405 -2.026 5.473 1.00 47.00 ? 2005 NAG A C3 1 HETATM 7016 C C4 . NAG D 3 . ? -25.898 -2.322 5.411 1.00 48.67 ? 2005 NAG A C4 1 HETATM 7017 C C5 . NAG D 3 . ? -25.162 -1.063 5.848 1.00 48.89 ? 2005 NAG A C5 1 HETATM 7018 C C6 . NAG D 3 . ? -23.635 -1.218 5.864 1.00 50.77 ? 2005 NAG A C6 1 HETATM 7019 C C7 . NAG D 3 . ? -30.201 -0.201 4.099 1.00 44.07 ? 2005 NAG A C7 1 HETATM 7020 C C8 . NAG D 3 . ? -31.485 0.359 4.651 1.00 44.29 ? 2005 NAG A C8 1 HETATM 7021 N N2 . NAG D 3 . ? -29.206 -0.400 4.975 1.00 44.50 ? 2005 NAG A N2 1 HETATM 7022 O O3 . NAG D 3 . ? -28.101 -3.155 4.994 1.00 48.18 ? 2005 NAG A O3 1 HETATM 7023 O O4 . NAG D 3 . ? -25.546 -3.449 6.208 1.00 51.16 ? 2005 NAG A O4 1 HETATM 7024 O O5 . NAG D 3 . ? -25.526 -0.056 4.913 1.00 46.83 ? 2005 NAG A O5 1 HETATM 7025 O O6 . NAG D 3 . ? -23.042 -0.125 6.551 1.00 52.73 ? 2005 NAG A O6 1 HETATM 7026 O O7 . NAG D 3 . ? -30.132 -0.443 2.893 1.00 43.35 ? 2005 NAG A O7 1 HETATM 7027 S S . SO4 E 4 . ? -38.965 39.629 -28.868 1.00 38.60 ? 4001 SO4 A S 1 HETATM 7028 O O1 . SO4 E 4 . ? -37.929 39.764 -29.881 1.00 40.45 ? 4001 SO4 A O1 1 HETATM 7029 O O2 . SO4 E 4 . ? -40.260 39.228 -29.397 1.00 40.07 ? 4001 SO4 A O2 1 HETATM 7030 O O3 . SO4 E 4 . ? -38.503 38.646 -27.911 1.00 41.85 ? 4001 SO4 A O3 1 HETATM 7031 O O4 . SO4 E 4 . ? -39.111 40.853 -28.103 1.00 41.83 ? 4001 SO4 A O4 1 HETATM 7032 C C1 . GOL F 5 . ? -21.747 25.546 -28.426 1.00 40.42 ? 3001 GOL A C1 1 HETATM 7033 O O1 . GOL F 5 . ? -21.113 26.390 -29.358 1.00 46.73 ? 3001 GOL A O1 1 HETATM 7034 C C2 . GOL F 5 . ? -21.644 26.200 -27.060 1.00 40.67 ? 3001 GOL A C2 1 HETATM 7035 O O2 . GOL F 5 . ? -22.613 27.241 -26.984 1.00 39.99 ? 3001 GOL A O2 1 HETATM 7036 C C3 . GOL F 5 . ? -21.851 25.137 -25.979 1.00 37.47 ? 3001 GOL A C3 1 HETATM 7037 O O3 . GOL F 5 . ? -21.254 23.919 -26.385 1.00 35.51 ? 3001 GOL A O3 1 HETATM 7038 C C1 . GOL G 5 . ? -26.998 2.069 -26.423 1.00 27.87 ? 3002 GOL A C1 1 HETATM 7039 O O1 . GOL G 5 . ? -26.080 2.217 -27.478 1.00 28.75 ? 3002 GOL A O1 1 HETATM 7040 C C2 . GOL G 5 . ? -27.290 3.446 -25.817 1.00 29.57 ? 3002 GOL A C2 1 HETATM 7041 O O2 . GOL G 5 . ? -26.143 4.268 -25.918 1.00 31.00 ? 3002 GOL A O2 1 HETATM 7042 C C3 . GOL G 5 . ? -28.426 4.108 -26.600 1.00 29.77 ? 3002 GOL A C3 1 HETATM 7043 O O3 . GOL G 5 . ? -28.702 5.388 -26.060 1.00 31.16 ? 3002 GOL A O3 1 HETATM 7044 C C1 . GOL H 5 . ? -27.927 -25.004 -15.472 1.00 36.95 ? 3003 GOL A C1 1 HETATM 7045 O O1 . GOL H 5 . ? -29.117 -25.326 -14.779 1.00 39.82 ? 3003 GOL A O1 1 HETATM 7046 C C2 . GOL H 5 . ? -27.427 -23.656 -14.991 1.00 37.02 ? 3003 GOL A C2 1 HETATM 7047 O O2 . GOL H 5 . ? -27.557 -23.618 -13.590 1.00 37.54 ? 3003 GOL A O2 1 HETATM 7048 C C3 . GOL H 5 . ? -25.953 -23.535 -15.355 1.00 35.04 ? 3003 GOL A C3 1 HETATM 7049 O O3 . GOL H 5 . ? -25.493 -22.214 -15.139 1.00 32.62 ? 3003 GOL A O3 1 HETATM 7050 C C1 . GOL I 5 . ? -26.180 7.600 -34.949 1.00 45.26 ? 3004 GOL A C1 1 HETATM 7051 O O1 . GOL I 5 . ? -26.122 6.187 -34.844 1.00 41.65 ? 3004 GOL A O1 1 HETATM 7052 C C2 . GOL I 5 . ? -26.949 8.049 -36.197 1.00 44.10 ? 3004 GOL A C2 1 HETATM 7053 O O2 . GOL I 5 . ? -27.995 7.139 -36.449 1.00 43.04 ? 3004 GOL A O2 1 HETATM 7054 C C3 . GOL I 5 . ? -27.458 9.487 -36.091 1.00 44.35 ? 3004 GOL A C3 1 HETATM 7055 O O3 . GOL I 5 . ? -26.480 10.495 -36.245 1.00 43.10 ? 3004 GOL A O3 1 HETATM 7056 C C1 . GOL J 5 . ? -24.039 -5.765 -34.919 1.00 45.62 ? 3005 GOL A C1 1 HETATM 7057 O O1 . GOL J 5 . ? -24.941 -4.686 -35.079 1.00 43.74 ? 3005 GOL A O1 1 HETATM 7058 C C2 . GOL J 5 . ? -22.654 -5.130 -34.837 1.00 45.56 ? 3005 GOL A C2 1 HETATM 7059 O O2 . GOL J 5 . ? -22.377 -4.766 -33.496 1.00 40.33 ? 3005 GOL A O2 1 HETATM 7060 C C3 . GOL J 5 . ? -21.614 -6.069 -35.442 1.00 45.99 ? 3005 GOL A C3 1 HETATM 7061 O O3 . GOL J 5 . ? -21.377 -7.170 -34.580 1.00 45.37 ? 3005 GOL A O3 1 HETATM 7062 C C1 . GOL K 5 . ? -27.133 43.082 -14.342 1.00 40.13 ? 3006 GOL A C1 1 HETATM 7063 O O1 . GOL K 5 . ? -28.179 43.244 -13.403 1.00 38.41 ? 3006 GOL A O1 1 HETATM 7064 C C2 . GOL K 5 . ? -27.575 42.352 -15.606 1.00 41.71 ? 3006 GOL A C2 1 HETATM 7065 O O2 . GOL K 5 . ? -28.568 43.069 -16.300 1.00 43.34 ? 3006 GOL A O2 1 HETATM 7066 C C3 . GOL K 5 . ? -26.388 42.341 -16.549 1.00 42.02 ? 3006 GOL A C3 1 HETATM 7067 O O3 . GOL K 5 . ? -26.132 43.639 -17.029 1.00 39.69 ? 3006 GOL A O3 1 HETATM 7068 C C1 . GOL L 5 . ? -50.712 -14.563 -5.551 1.00 42.26 ? 3007 GOL A C1 1 HETATM 7069 O O1 . GOL L 5 . ? -51.532 -13.711 -4.777 1.00 47.18 ? 3007 GOL A O1 1 HETATM 7070 C C2 . GOL L 5 . ? -49.389 -13.853 -5.807 1.00 38.78 ? 3007 GOL A C2 1 HETATM 7071 O O2 . GOL L 5 . ? -48.418 -14.802 -6.218 1.00 37.42 ? 3007 GOL A O2 1 HETATM 7072 C C3 . GOL L 5 . ? -49.621 -12.871 -6.941 1.00 36.13 ? 3007 GOL A C3 1 HETATM 7073 O O3 . GOL L 5 . ? -48.412 -12.739 -7.670 1.00 30.28 ? 3007 GOL A O3 1 HETATM 7074 C C1 . GOL M 5 . ? -53.676 -4.054 -19.009 1.00 48.21 ? 3008 GOL A C1 1 HETATM 7075 O O1 . GOL M 5 . ? -53.498 -4.392 -17.666 1.00 51.39 ? 3008 GOL A O1 1 HETATM 7076 C C2 . GOL M 5 . ? -53.412 -5.282 -19.868 1.00 47.72 ? 3008 GOL A C2 1 HETATM 7077 O O2 . GOL M 5 . ? -53.837 -4.996 -21.178 1.00 47.43 ? 3008 GOL A O2 1 HETATM 7078 C C3 . GOL M 5 . ? -51.928 -5.623 -19.914 1.00 45.42 ? 3008 GOL A C3 1 HETATM 7079 O O3 . GOL M 5 . ? -51.780 -7.024 -19.937 1.00 43.70 ? 3008 GOL A O3 1 HETATM 7080 C C1 . GOL N 5 . ? -52.530 -16.204 -12.377 1.00 67.47 ? 3009 GOL A C1 1 HETATM 7081 O O1 . GOL N 5 . ? -52.982 -17.197 -13.276 1.00 67.10 ? 3009 GOL A O1 1 HETATM 7082 C C2 . GOL N 5 . ? -53.339 -16.263 -11.085 1.00 68.24 ? 3009 GOL A C2 1 HETATM 7083 O O2 . GOL N 5 . ? -52.847 -15.328 -10.138 1.00 68.02 ? 3009 GOL A O2 1 HETATM 7084 C C3 . GOL N 5 . ? -54.799 -15.960 -11.401 1.00 68.46 ? 3009 GOL A C3 1 HETATM 7085 O O3 . GOL N 5 . ? -55.465 -15.548 -10.226 1.00 69.65 ? 3009 GOL A O3 1 HETATM 7086 C C1 . NAG O 3 . ? 3.105 8.055 -16.836 1.00 28.02 ? 2003 NAG X C1 1 HETATM 7087 C C2 . NAG O 3 . ? 2.975 9.337 -17.667 1.00 30.06 ? 2003 NAG X C2 1 HETATM 7088 C C3 . NAG O 3 . ? 3.603 9.197 -19.066 1.00 31.67 ? 2003 NAG X C3 1 HETATM 7089 C C4 . NAG O 3 . ? 5.039 8.692 -19.003 1.00 32.48 ? 2003 NAG X C4 1 HETATM 7090 C C5 . NAG O 3 . ? 5.073 7.487 -18.071 1.00 31.20 ? 2003 NAG X C5 1 HETATM 7091 C C6 . NAG O 3 . ? 6.520 7.049 -17.862 1.00 29.24 ? 2003 NAG X C6 1 HETATM 7092 C C7 . NAG O 3 . ? 1.165 10.889 -17.292 1.00 32.80 ? 2003 NAG X C7 1 HETATM 7093 C C8 . NAG O 3 . ? -0.315 11.160 -17.378 1.00 33.56 ? 2003 NAG X C8 1 HETATM 7094 N N2 . NAG O 3 . ? 1.589 9.743 -17.789 1.00 31.58 ? 2003 NAG X N2 1 HETATM 7095 O O3 . NAG O 3 . ? 3.558 10.431 -19.720 1.00 28.34 ? 2003 NAG X O3 1 HETATM 7096 O O4 . NAG O 3 . ? 5.515 8.244 -20.267 1.00 39.56 ? 2003 NAG X O4 1 HETATM 7097 O O5 . NAG O 3 . ? 4.485 7.742 -16.807 1.00 28.87 ? 2003 NAG X O5 1 HETATM 7098 O O6 . NAG O 3 . ? 6.524 5.850 -17.112 1.00 32.53 ? 2003 NAG X O6 1 HETATM 7099 O O7 . NAG O 3 . ? 1.920 11.708 -16.776 1.00 35.25 ? 2003 NAG X O7 1 HETATM 7100 C C1 . NAG P 3 . ? 6.048 9.281 -21.115 1.00 44.54 ? 2004 NAG X C1 1 HETATM 7101 C C2 . NAG P 3 . ? 7.495 8.948 -21.500 1.00 47.18 ? 2004 NAG X C2 1 HETATM 7102 C C3 . NAG P 3 . ? 8.074 9.835 -22.598 1.00 49.16 ? 2004 NAG X C3 1 HETATM 7103 C C4 . NAG P 3 . ? 7.086 9.989 -23.754 1.00 49.84 ? 2004 NAG X C4 1 HETATM 7104 C C5 . NAG P 3 . ? 5.726 10.409 -23.179 1.00 49.17 ? 2004 NAG X C5 1 HETATM 7105 C C6 . NAG P 3 . ? 4.683 10.614 -24.273 1.00 49.35 ? 2004 NAG X C6 1 HETATM 7106 C C7 . NAG P 3 . ? 9.160 8.057 -20.001 1.00 51.79 ? 2004 NAG X C7 1 HETATM 7107 C C8 . NAG P 3 . ? 9.949 8.248 -18.733 1.00 52.06 ? 2004 NAG X C8 1 HETATM 7108 N N2 . NAG P 3 . ? 8.363 9.062 -20.355 1.00 49.64 ? 2004 NAG X N2 1 HETATM 7109 O O3 . NAG P 3 . ? 9.281 9.249 -23.042 1.00 49.97 ? 2004 NAG X O3 1 HETATM 7110 O O4 . NAG P 3 . ? 7.580 10.935 -24.698 1.00 52.89 ? 2004 NAG X O4 1 HETATM 7111 O O5 . NAG P 3 . ? 5.253 9.416 -22.270 1.00 46.23 ? 2004 NAG X O5 1 HETATM 7112 O O6 . NAG P 3 . ? 4.192 9.337 -24.611 1.00 48.98 ? 2004 NAG X O6 1 HETATM 7113 O O7 . NAG P 3 . ? 9.263 7.021 -20.665 1.00 53.47 ? 2004 NAG X O7 1 HETATM 7114 O O . HOH Q 6 . ? -25.613 11.809 -20.971 1.00 14.30 ? 4002 HOH A O 1 HETATM 7115 O O . HOH Q 6 . ? -29.825 -14.263 -14.863 1.00 17.71 ? 4003 HOH A O 1 HETATM 7116 O O . HOH Q 6 . ? -15.340 33.607 -15.096 1.00 19.90 ? 4004 HOH A O 1 HETATM 7117 O O . HOH Q 6 . ? -33.180 -3.763 -23.867 1.00 14.13 ? 4005 HOH A O 1 HETATM 7118 O O . HOH Q 6 . ? -41.642 -6.857 -33.388 1.00 17.51 ? 4006 HOH A O 1 HETATM 7119 O O . HOH Q 6 . ? -29.887 9.248 -9.416 1.00 19.88 ? 4007 HOH A O 1 HETATM 7120 O O . HOH Q 6 . ? -23.556 6.010 -13.495 1.00 19.83 ? 4008 HOH A O 1 HETATM 7121 O O . HOH Q 6 . ? -26.786 -0.049 -29.143 1.00 14.28 ? 4009 HOH A O 1 HETATM 7122 O O . HOH Q 6 . ? -10.332 11.771 1.614 1.00 16.95 ? 4010 HOH A O 1 HETATM 7123 O O . HOH Q 6 . ? -21.784 13.942 -24.554 1.00 13.07 ? 4011 HOH A O 1 HETATM 7124 O O . HOH Q 6 . ? -35.456 12.807 -8.800 1.00 17.27 ? 4012 HOH A O 1 HETATM 7125 O O . HOH Q 6 . ? -26.072 15.741 -15.021 1.00 16.97 ? 4013 HOH A O 1 HETATM 7126 O O . HOH Q 6 . ? -35.419 -17.417 -27.922 1.00 19.29 ? 4014 HOH A O 1 HETATM 7127 O O . HOH Q 6 . ? -29.566 -2.905 -10.956 1.00 16.75 ? 4015 HOH A O 1 HETATM 7128 O O . HOH Q 6 . ? -29.785 24.399 -24.432 1.00 14.36 ? 4016 HOH A O 1 HETATM 7129 O O . HOH Q 6 . ? -21.850 9.388 -7.108 1.00 14.16 ? 4017 HOH A O 1 HETATM 7130 O O . HOH Q 6 . ? -2.005 2.379 -13.290 1.00 20.60 ? 4018 HOH A O 1 HETATM 7131 O O . HOH Q 6 . ? -22.268 25.454 21.640 1.00 23.11 ? 4019 HOH A O 1 HETATM 7132 O O . HOH Q 6 . ? -18.977 23.193 15.623 1.00 23.69 ? 4020 HOH A O 1 HETATM 7133 O O . HOH Q 6 . ? -15.669 22.796 -15.001 1.00 19.13 ? 4021 HOH A O 1 HETATM 7134 O O . HOH Q 6 . ? -28.101 3.028 -9.306 1.00 20.46 ? 4022 HOH A O 1 HETATM 7135 O O . HOH Q 6 . ? -36.562 -19.278 -29.497 1.00 24.18 ? 4023 HOH A O 1 HETATM 7136 O O . HOH Q 6 . ? -33.489 -2.193 -8.568 1.00 12.26 ? 4024 HOH A O 1 HETATM 7137 O O . HOH Q 6 . ? -26.577 11.933 -23.523 1.00 18.93 ? 4025 HOH A O 1 HETATM 7138 O O . HOH Q 6 . ? -26.320 13.843 -18.199 1.00 13.62 ? 4026 HOH A O 1 HETATM 7139 O O . HOH Q 6 . ? -25.443 31.383 -2.620 1.00 18.95 ? 4027 HOH A O 1 HETATM 7140 O O . HOH Q 6 . ? -34.717 5.284 -6.465 1.00 19.81 ? 4028 HOH A O 1 HETATM 7141 O O . HOH Q 6 . ? -51.447 1.027 -17.062 1.00 15.82 ? 4029 HOH A O 1 HETATM 7142 O O . HOH Q 6 . ? -44.059 8.606 -13.375 1.00 17.21 ? 4030 HOH A O 1 HETATM 7143 O O . HOH Q 6 . ? -12.629 16.191 -5.744 1.00 20.39 ? 4031 HOH A O 1 HETATM 7144 O O . HOH Q 6 . ? -43.271 17.870 -21.102 1.00 18.67 ? 4032 HOH A O 1 HETATM 7145 O O . HOH Q 6 . ? -29.161 -18.558 -15.120 1.00 21.09 ? 4033 HOH A O 1 HETATM 7146 O O . HOH Q 6 . ? -28.036 6.074 -3.037 1.00 21.41 ? 4034 HOH A O 1 HETATM 7147 O O . HOH Q 6 . ? -42.135 10.948 -6.260 1.00 18.40 ? 4035 HOH A O 1 HETATM 7148 O O . HOH Q 6 . ? -19.160 37.252 -21.263 1.00 21.44 ? 4036 HOH A O 1 HETATM 7149 O O . HOH Q 6 . ? -39.543 -5.472 -34.574 1.00 17.42 ? 4037 HOH A O 1 HETATM 7150 O O . HOH Q 6 . ? -14.051 22.773 -12.790 1.00 15.86 ? 4038 HOH A O 1 HETATM 7151 O O . HOH Q 6 . ? -6.088 -8.393 -16.786 1.00 20.78 ? 4039 HOH A O 1 HETATM 7152 O O . HOH Q 6 . ? -45.155 11.562 -12.575 1.00 16.34 ? 4040 HOH A O 1 HETATM 7153 O O . HOH Q 6 . ? -33.310 -4.279 -17.111 1.00 18.46 ? 4041 HOH A O 1 HETATM 7154 O O . HOH Q 6 . ? -11.658 7.207 -11.193 1.00 19.97 ? 4042 HOH A O 1 HETATM 7155 O O . HOH Q 6 . ? -15.776 24.588 -16.908 1.00 20.76 ? 4043 HOH A O 1 HETATM 7156 O O . HOH Q 6 . ? -40.053 34.083 -20.732 1.00 19.36 ? 4044 HOH A O 1 HETATM 7157 O O . HOH Q 6 . ? -31.303 5.143 -0.712 1.00 22.29 ? 4045 HOH A O 1 HETATM 7158 O O . HOH Q 6 . ? -41.809 31.918 -20.379 1.00 24.05 ? 4046 HOH A O 1 HETATM 7159 O O . HOH Q 6 . ? -17.161 6.852 -1.476 1.00 21.06 ? 4047 HOH A O 1 HETATM 7160 O O . HOH Q 6 . ? -32.626 2.927 -8.674 1.00 21.60 ? 4048 HOH A O 1 HETATM 7161 O O . HOH Q 6 . ? -15.719 7.567 -13.130 1.00 18.44 ? 4049 HOH A O 1 HETATM 7162 O O . HOH Q 6 . ? -9.177 25.323 0.296 1.00 17.37 ? 4050 HOH A O 1 HETATM 7163 O O . HOH Q 6 . ? -28.442 24.658 4.607 1.00 17.97 ? 4051 HOH A O 1 HETATM 7164 O O . HOH Q 6 . ? -18.819 10.418 4.916 1.00 29.27 ? 4052 HOH A O 1 HETATM 7165 O O . HOH Q 6 . ? -57.070 11.207 -24.528 1.00 19.71 ? 4053 HOH A O 1 HETATM 7166 O O . HOH Q 6 . ? -11.291 -3.441 -13.565 1.00 21.88 ? 4054 HOH A O 1 HETATM 7167 O O . HOH Q 6 . ? -36.298 -5.337 -41.945 1.00 21.44 ? 4055 HOH A O 1 HETATM 7168 O O . HOH Q 6 . ? -44.906 -5.952 -11.827 1.00 21.12 ? 4056 HOH A O 1 HETATM 7169 O O . HOH Q 6 . ? -36.576 14.916 -34.225 1.00 24.90 ? 4057 HOH A O 1 HETATM 7170 O O . HOH Q 6 . ? -21.806 -2.301 -6.395 1.00 18.36 ? 4058 HOH A O 1 HETATM 7171 O O . HOH Q 6 . ? -29.771 24.478 0.232 1.00 22.50 ? 4059 HOH A O 1 HETATM 7172 O O . HOH Q 6 . ? -14.402 20.196 -11.697 1.00 19.66 ? 4060 HOH A O 1 HETATM 7173 O O . HOH Q 6 . ? -27.279 -20.375 -14.096 1.00 21.71 ? 4061 HOH A O 1 HETATM 7174 O O . HOH Q 6 . ? -40.889 11.386 -27.815 1.00 20.10 ? 4062 HOH A O 1 HETATM 7175 O O . HOH Q 6 . ? -29.635 -16.575 -13.288 1.00 18.84 ? 4063 HOH A O 1 HETATM 7176 O O . HOH Q 6 . ? -46.509 7.223 -32.572 1.00 17.08 ? 4064 HOH A O 1 HETATM 7177 O O . HOH Q 6 . ? -26.214 16.132 -29.393 1.00 21.94 ? 4065 HOH A O 1 HETATM 7178 O O . HOH Q 6 . ? -24.582 48.484 -21.252 1.00 22.88 ? 4066 HOH A O 1 HETATM 7179 O O . HOH Q 6 . ? -1.474 -11.809 -16.090 1.00 25.55 ? 4067 HOH A O 1 HETATM 7180 O O . HOH Q 6 . ? -32.805 7.110 -7.721 1.00 16.01 ? 4068 HOH A O 1 HETATM 7181 O O . HOH Q 6 . ? -24.948 -1.955 -34.724 1.00 20.71 ? 4069 HOH A O 1 HETATM 7182 O O . HOH Q 6 . ? -19.433 13.966 -24.514 1.00 17.28 ? 4070 HOH A O 1 HETATM 7183 O O . HOH Q 6 . ? -47.248 3.576 -45.589 1.00 25.12 ? 4071 HOH A O 1 HETATM 7184 O O . HOH Q 6 . ? -14.343 6.718 -2.796 1.00 27.73 ? 4072 HOH A O 1 HETATM 7185 O O . HOH Q 6 . ? -9.460 21.803 -8.413 1.00 21.41 ? 4073 HOH A O 1 HETATM 7186 O O . HOH Q 6 . ? -11.886 20.211 0.626 1.00 21.20 ? 4074 HOH A O 1 HETATM 7187 O O . HOH Q 6 . ? -28.605 21.998 5.655 1.00 18.52 ? 4075 HOH A O 1 HETATM 7188 O O . HOH Q 6 . ? -19.528 6.622 -18.966 1.00 18.34 ? 4076 HOH A O 1 HETATM 7189 O O . HOH Q 6 . ? -28.782 -16.377 -16.944 1.00 18.14 ? 4077 HOH A O 1 HETATM 7190 O O . HOH Q 6 . ? -32.004 18.284 -27.651 1.00 19.31 ? 4078 HOH A O 1 HETATM 7191 O O . HOH Q 6 . ? -9.882 30.176 -12.334 1.00 21.49 ? 4079 HOH A O 1 HETATM 7192 O O . HOH Q 6 . ? -30.645 3.412 -42.718 1.00 24.28 ? 4080 HOH A O 1 HETATM 7193 O O . HOH Q 6 . ? -16.284 -6.859 -13.674 1.00 24.84 ? 4081 HOH A O 1 HETATM 7194 O O . HOH Q 6 . ? -29.718 -0.911 -8.963 1.00 22.44 ? 4082 HOH A O 1 HETATM 7195 O O . HOH Q 6 . ? -28.058 31.773 6.141 1.00 21.23 ? 4083 HOH A O 1 HETATM 7196 O O . HOH Q 6 . ? -53.767 13.999 -15.559 1.00 21.78 ? 4084 HOH A O 1 HETATM 7197 O O . HOH Q 6 . ? -33.958 14.513 -1.508 1.00 22.38 ? 4085 HOH A O 1 HETATM 7198 O O . HOH Q 6 . ? -15.161 2.827 -6.205 1.00 19.90 ? 4086 HOH A O 1 HETATM 7199 O O . HOH Q 6 . ? -46.354 6.598 -7.458 1.00 23.09 ? 4087 HOH A O 1 HETATM 7200 O O . HOH Q 6 . ? -36.319 30.717 -7.216 1.00 18.91 ? 4088 HOH A O 1 HETATM 7201 O O . HOH Q 6 . ? -24.192 25.445 3.352 1.00 23.69 ? 4089 HOH A O 1 HETATM 7202 O O . HOH Q 6 . ? -11.406 -1.425 -11.866 1.00 26.32 ? 4090 HOH A O 1 HETATM 7203 O O . HOH Q 6 . ? -62.279 0.626 -27.580 1.00 20.97 ? 4091 HOH A O 1 HETATM 7204 O O . HOH Q 6 . ? -47.727 0.630 -9.640 1.00 25.11 ? 4092 HOH A O 1 HETATM 7205 O O . HOH Q 6 . ? -25.354 4.068 -31.212 1.00 24.09 ? 4093 HOH A O 1 HETATM 7206 O O . HOH Q 6 . ? -24.301 29.243 -0.228 1.00 20.87 ? 4094 HOH A O 1 HETATM 7207 O O . HOH Q 6 . ? -39.645 28.669 -21.718 1.00 26.24 ? 4095 HOH A O 1 HETATM 7208 O O . HOH Q 6 . ? -49.469 15.950 -22.754 1.00 19.79 ? 4096 HOH A O 1 HETATM 7209 O O . HOH Q 6 . ? -29.917 -12.687 -7.753 1.00 12.92 ? 4097 HOH A O 1 HETATM 7210 O O . HOH Q 6 . ? -6.211 -8.046 -27.068 1.00 25.17 ? 4098 HOH A O 1 HETATM 7211 O O . HOH Q 6 . ? -42.400 -16.375 -4.159 1.00 26.64 ? 4099 HOH A O 1 HETATM 7212 O O . HOH Q 6 . ? -8.092 23.705 -9.863 1.00 26.23 ? 4100 HOH A O 1 HETATM 7213 O O . HOH Q 6 . ? -14.632 32.359 -0.172 1.00 24.71 ? 4101 HOH A O 1 HETATM 7214 O O . HOH Q 6 . ? -29.056 -5.148 -15.992 1.00 19.62 ? 4102 HOH A O 1 HETATM 7215 O O . HOH Q 6 . ? -54.191 -7.857 -3.682 1.00 29.68 ? 4103 HOH A O 1 HETATM 7216 O O . HOH Q 6 . ? -25.565 24.393 11.974 1.00 21.03 ? 4104 HOH A O 1 HETATM 7217 O O . HOH Q 6 . ? -27.340 3.833 -1.470 1.00 25.02 ? 4105 HOH A O 1 HETATM 7218 O O . HOH Q 6 . ? -38.814 9.927 -27.076 1.00 20.65 ? 4106 HOH A O 1 HETATM 7219 O O . HOH Q 6 . ? -8.582 -7.415 -16.881 1.00 22.25 ? 4107 HOH A O 1 HETATM 7220 O O . HOH Q 6 . ? -33.278 -7.910 -39.768 1.00 29.29 ? 4108 HOH A O 1 HETATM 7221 O O . HOH Q 6 . ? -25.936 21.509 5.336 1.00 22.09 ? 4109 HOH A O 1 HETATM 7222 O O . HOH Q 6 . ? -21.379 25.715 4.100 1.00 21.50 ? 4110 HOH A O 1 HETATM 7223 O O . HOH Q 6 . ? -30.475 39.990 -18.685 1.00 25.64 ? 4111 HOH A O 1 HETATM 7224 O O . HOH Q 6 . ? -24.896 19.076 4.506 1.00 23.88 ? 4112 HOH A O 1 HETATM 7225 O O . HOH Q 6 . ? -2.925 -2.732 -27.847 1.00 21.62 ? 4113 HOH A O 1 HETATM 7226 O O . HOH Q 6 . ? 2.027 4.575 -18.040 1.00 26.31 ? 4114 HOH A O 1 HETATM 7227 O O . HOH Q 6 . ? -27.906 22.107 13.264 1.00 29.70 ? 4115 HOH A O 1 HETATM 7228 O O . HOH Q 6 . ? -34.061 -5.602 -40.811 1.00 22.01 ? 4116 HOH A O 1 HETATM 7229 O O . HOH Q 6 . ? -11.286 12.525 3.910 1.00 31.11 ? 4117 HOH A O 1 HETATM 7230 O O . HOH Q 6 . ? -7.311 -16.463 -24.674 1.00 30.66 ? 4118 HOH A O 1 HETATM 7231 O O . HOH Q 6 . ? -31.896 -15.892 -7.906 1.00 25.29 ? 4119 HOH A O 1 HETATM 7232 O O . HOH Q 6 . ? -25.668 19.073 -29.031 1.00 25.39 ? 4120 HOH A O 1 HETATM 7233 O O . HOH Q 6 . ? -13.361 13.778 -9.108 1.00 23.63 ? 4121 HOH A O 1 HETATM 7234 O O . HOH Q 6 . ? -60.171 -7.662 -39.617 1.00 24.01 ? 4122 HOH A O 1 HETATM 7235 O O . HOH Q 6 . ? -41.524 2.811 -7.545 1.00 25.95 ? 4123 HOH A O 1 HETATM 7236 O O . HOH Q 6 . ? -12.283 -15.927 -15.591 1.00 21.81 ? 4124 HOH A O 1 HETATM 7237 O O . HOH Q 6 . ? -16.009 -16.005 -32.440 1.00 30.25 ? 4125 HOH A O 1 HETATM 7238 O O . HOH Q 6 . ? -38.112 -8.938 -49.614 1.00 20.53 ? 4126 HOH A O 1 HETATM 7239 O O . HOH Q 6 . ? -43.602 29.778 -13.649 1.00 26.37 ? 4127 HOH A O 1 HETATM 7240 O O . HOH Q 6 . ? -21.064 -15.060 -17.529 1.00 27.16 ? 4128 HOH A O 1 HETATM 7241 O O . HOH Q 6 . ? -45.087 4.393 -44.527 1.00 33.76 ? 4129 HOH A O 1 HETATM 7242 O O . HOH Q 6 . ? -17.497 8.923 -15.344 1.00 21.34 ? 4130 HOH A O 1 HETATM 7243 O O . HOH Q 6 . ? -45.845 32.960 -18.369 1.00 29.92 ? 4131 HOH A O 1 HETATM 7244 O O . HOH Q 6 . ? -39.192 15.132 -14.131 1.00 22.21 ? 4132 HOH A O 1 HETATM 7245 O O . HOH Q 6 . ? -15.028 23.136 -19.208 1.00 24.94 ? 4133 HOH A O 1 HETATM 7246 O O . HOH Q 6 . ? -13.584 -19.829 -16.187 1.00 26.30 ? 4134 HOH A O 1 HETATM 7247 O O . HOH Q 6 . ? -22.060 -11.883 -6.897 1.00 26.70 ? 4135 HOH A O 1 HETATM 7248 O O . HOH Q 6 . ? -42.203 -14.462 -30.208 1.00 30.83 ? 4136 HOH A O 1 HETATM 7249 O O . HOH Q 6 . ? -2.647 -9.669 -11.875 1.00 24.32 ? 4137 HOH A O 1 HETATM 7250 O O . HOH Q 6 . ? -43.741 -19.513 -11.735 1.00 23.52 ? 4138 HOH A O 1 HETATM 7251 O O . HOH Q 6 . ? -47.541 -6.231 -12.623 1.00 22.74 ? 4139 HOH A O 1 HETATM 7252 O O . HOH Q 6 . ? -22.536 15.669 -14.058 1.00 23.75 ? 4140 HOH A O 1 HETATM 7253 O O . HOH Q 6 . ? 0.401 7.181 -18.912 1.00 20.74 ? 4141 HOH A O 1 HETATM 7254 O O . HOH Q 6 . ? -5.764 18.340 -12.094 1.00 29.05 ? 4142 HOH A O 1 HETATM 7255 O O . HOH Q 6 . ? -46.623 -17.103 -23.056 1.00 28.28 ? 4143 HOH A O 1 HETATM 7256 O O . HOH Q 6 . ? -43.774 13.032 -27.089 1.00 24.99 ? 4144 HOH A O 1 HETATM 7257 O O . HOH Q 6 . ? -7.234 29.405 -7.532 1.00 26.27 ? 4145 HOH A O 1 HETATM 7258 O O . HOH Q 6 . ? -41.244 14.935 -25.728 1.00 23.37 ? 4146 HOH A O 1 HETATM 7259 O O . HOH Q 6 . ? -48.225 -2.460 -6.027 1.00 34.60 ? 4147 HOH A O 1 HETATM 7260 O O . HOH Q 6 . ? -60.981 -8.293 -47.920 1.00 31.06 ? 4148 HOH A O 1 HETATM 7261 O O . HOH Q 6 . ? -39.989 -2.232 -47.032 1.00 22.91 ? 4149 HOH A O 1 HETATM 7262 O O . HOH Q 6 . ? -53.481 16.555 -17.200 1.00 26.31 ? 4150 HOH A O 1 HETATM 7263 O O . HOH Q 6 . ? -48.108 -11.362 -25.901 1.00 23.62 ? 4151 HOH A O 1 HETATM 7264 O O . HOH Q 6 . ? -36.417 -15.060 -34.295 1.00 31.03 ? 4152 HOH A O 1 HETATM 7265 O O . HOH Q 6 . ? -40.078 -18.738 -4.092 1.00 34.12 ? 4153 HOH A O 1 HETATM 7266 O O . HOH Q 6 . ? -41.923 -21.636 -11.027 1.00 28.62 ? 4154 HOH A O 1 HETATM 7267 O O . HOH Q 6 . ? -31.698 -0.774 -5.550 1.00 28.22 ? 4155 HOH A O 1 HETATM 7268 O O . HOH Q 6 . ? -32.899 -17.465 -31.133 1.00 25.80 ? 4156 HOH A O 1 HETATM 7269 O O . HOH Q 6 . ? -66.437 6.611 -33.853 1.00 29.49 ? 4157 HOH A O 1 HETATM 7270 O O . HOH Q 6 . ? -45.385 -13.720 -33.847 1.00 29.79 ? 4158 HOH A O 1 HETATM 7271 O O . HOH Q 6 . ? -24.419 1.351 1.839 1.00 28.88 ? 4159 HOH A O 1 HETATM 7272 O O . HOH Q 6 . ? -22.955 8.408 1.829 1.00 26.92 ? 4160 HOH A O 1 HETATM 7273 O O . HOH Q 6 . ? -20.365 26.768 -23.048 1.00 24.50 ? 4161 HOH A O 1 HETATM 7274 O O . HOH Q 6 . ? -9.513 7.569 -17.731 1.00 26.85 ? 4162 HOH A O 1 HETATM 7275 O O . HOH Q 6 . ? -30.548 4.262 -8.864 1.00 22.12 ? 4163 HOH A O 1 HETATM 7276 O O . HOH Q 6 . ? -10.757 -8.161 -15.119 1.00 27.47 ? 4164 HOH A O 1 HETATM 7277 O O . HOH Q 6 . ? -31.259 31.326 -29.330 1.00 32.68 ? 4165 HOH A O 1 HETATM 7278 O O . HOH Q 6 . ? -26.897 24.595 2.417 1.00 24.72 ? 4166 HOH A O 1 HETATM 7279 O O . HOH Q 6 . ? -23.177 21.788 -26.922 1.00 23.94 ? 4167 HOH A O 1 HETATM 7280 O O . HOH Q 6 . ? -48.177 -7.149 -43.832 1.00 43.39 ? 4168 HOH A O 1 HETATM 7281 O O . HOH Q 6 . ? -25.937 7.486 -32.560 1.00 29.83 ? 4169 HOH A O 1 HETATM 7282 O O . HOH Q 6 . ? -16.977 44.436 -11.862 1.00 25.92 ? 4170 HOH A O 1 HETATM 7283 O O . HOH Q 6 . ? -33.724 -2.984 -42.568 1.00 27.42 ? 4171 HOH A O 1 HETATM 7284 O O . HOH Q 6 . ? -49.710 25.080 -10.083 1.00 29.83 ? 4172 HOH A O 1 HETATM 7285 O O . HOH Q 6 . ? -36.716 29.769 -1.823 1.00 27.62 ? 4173 HOH A O 1 HETATM 7286 O O . HOH Q 6 . ? -63.366 -11.380 -37.410 1.00 500.00 ? 4174 HOH A O 1 HETATM 7287 O O . HOH Q 6 . ? -10.075 28.607 -14.776 1.00 24.70 ? 4175 HOH A O 1 HETATM 7288 O O . HOH Q 6 . ? -17.589 46.710 -23.146 1.00 28.47 ? 4176 HOH A O 1 HETATM 7289 O O . HOH Q 6 . ? -34.096 -15.893 -29.255 1.00 22.40 ? 4177 HOH A O 1 HETATM 7290 O O . HOH Q 6 . ? -40.876 34.502 -8.273 1.00 23.75 ? 4178 HOH A O 1 HETATM 7291 O O . HOH Q 6 . ? -43.682 -5.419 -0.800 1.00 26.95 ? 4179 HOH A O 1 HETATM 7292 O O . HOH Q 6 . ? -19.086 24.345 -19.530 1.00 26.20 ? 4180 HOH A O 1 HETATM 7293 O O . HOH Q 6 . ? -30.065 19.974 4.425 1.00 37.17 ? 4181 HOH A O 1 HETATM 7294 O O . HOH Q 6 . ? -19.987 6.235 5.340 1.00 28.47 ? 4182 HOH A O 1 HETATM 7295 O O . HOH Q 6 . ? -5.477 -13.642 -12.942 1.00 25.66 ? 4183 HOH A O 1 HETATM 7296 O O . HOH Q 6 . ? -9.983 -19.061 -15.599 1.00 27.62 ? 4184 HOH A O 1 HETATM 7297 O O . HOH Q 6 . ? -17.190 12.684 5.096 1.00 29.64 ? 4185 HOH A O 1 HETATM 7298 O O . HOH Q 6 . ? -71.379 1.461 -34.078 1.00 27.84 ? 4186 HOH A O 1 HETATM 7299 O O . HOH Q 6 . ? -38.305 -8.086 -0.094 1.00 28.66 ? 4187 HOH A O 1 HETATM 7300 O O . HOH Q 6 . ? -60.476 -7.380 -27.604 1.00 30.33 ? 4188 HOH A O 1 HETATM 7301 O O . HOH Q 6 . ? -35.256 -20.968 -10.679 1.00 34.62 ? 4189 HOH A O 1 HETATM 7302 O O . HOH Q 6 . ? -65.363 8.898 -38.729 1.00 37.72 ? 4190 HOH A O 1 HETATM 7303 O O . HOH Q 6 . ? -31.675 -6.196 -35.141 1.00 29.45 ? 4191 HOH A O 1 HETATM 7304 O O . HOH Q 6 . ? -32.832 2.454 -49.290 1.00 29.32 ? 4192 HOH A O 1 HETATM 7305 O O . HOH Q 6 . ? -46.004 9.271 -31.079 1.00 34.77 ? 4193 HOH A O 1 HETATM 7306 O O . HOH Q 6 . ? -42.342 -16.336 -28.266 1.00 25.37 ? 4194 HOH A O 1 HETATM 7307 O O . HOH Q 6 . ? -44.443 18.106 -23.570 1.00 23.46 ? 4195 HOH A O 1 HETATM 7308 O O . HOH Q 6 . ? -8.722 22.196 -5.663 1.00 27.59 ? 4196 HOH A O 1 HETATM 7309 O O . HOH Q 6 . ? -29.147 21.507 8.271 1.00 35.96 ? 4197 HOH A O 1 HETATM 7310 O O . HOH Q 6 . ? 1.347 1.998 -6.813 1.00 28.27 ? 4198 HOH A O 1 HETATM 7311 O O . HOH Q 6 . ? -62.673 0.340 -16.334 1.00 33.60 ? 4199 HOH A O 1 HETATM 7312 O O . HOH Q 6 . ? -16.985 -12.180 -6.485 1.00 29.31 ? 4200 HOH A O 1 HETATM 7313 O O . HOH Q 6 . ? -29.787 -3.088 -3.008 1.00 31.62 ? 4201 HOH A O 1 HETATM 7314 O O . HOH Q 6 . ? -31.575 26.718 -26.691 1.00 30.87 ? 4202 HOH A O 1 HETATM 7315 O O . HOH Q 6 . ? -46.578 11.924 -48.075 1.00 24.40 ? 4203 HOH A O 1 HETATM 7316 O O . HOH Q 6 . ? -31.002 -10.020 -33.250 1.00 34.04 ? 4204 HOH A O 1 HETATM 7317 O O . HOH Q 6 . ? -15.007 42.579 -15.442 1.00 32.51 ? 4205 HOH A O 1 HETATM 7318 O O . HOH Q 6 . ? -37.778 22.170 8.791 1.00 29.42 ? 4206 HOH A O 1 HETATM 7319 O O . HOH Q 6 . ? -17.517 -26.043 -20.902 1.00 30.40 ? 4207 HOH A O 1 HETATM 7320 O O . HOH Q 6 . ? -42.928 11.208 -29.367 1.00 28.88 ? 4208 HOH A O 1 HETATM 7321 O O . HOH Q 6 . ? -22.674 -19.074 -9.950 1.00 25.07 ? 4209 HOH A O 1 HETATM 7322 O O . HOH Q 6 . ? -10.794 3.579 -33.881 1.00 28.13 ? 4210 HOH A O 1 HETATM 7323 O O . HOH Q 6 . ? -28.645 5.647 -23.377 1.00 26.06 ? 4211 HOH A O 1 HETATM 7324 O O . HOH Q 6 . ? -37.602 32.050 -5.558 1.00 33.53 ? 4212 HOH A O 1 HETATM 7325 O O . HOH Q 6 . ? -14.923 17.052 6.222 1.00 30.63 ? 4213 HOH A O 1 HETATM 7326 O O . HOH Q 6 . ? -15.414 21.742 -22.736 1.00 30.68 ? 4214 HOH A O 1 HETATM 7327 O O . HOH Q 6 . ? -55.755 17.691 -16.416 1.00 26.35 ? 4215 HOH A O 1 HETATM 7328 O O . HOH Q 6 . ? -28.835 17.529 5.179 1.00 25.68 ? 4216 HOH A O 1 HETATM 7329 O O . HOH Q 6 . ? -44.647 -17.687 -5.550 1.00 34.02 ? 4217 HOH A O 1 HETATM 7330 O O . HOH Q 6 . ? -28.730 2.620 -44.227 1.00 27.82 ? 4218 HOH A O 1 HETATM 7331 O O . HOH Q 6 . ? -47.686 -9.948 -6.451 1.00 27.44 ? 4219 HOH A O 1 HETATM 7332 O O . HOH Q 6 . ? -46.101 -21.739 -11.880 1.00 33.68 ? 4220 HOH A O 1 HETATM 7333 O O . HOH Q 6 . ? -12.868 24.636 -20.262 1.00 30.82 ? 4221 HOH A O 1 HETATM 7334 O O . HOH Q 6 . ? -18.516 2.145 -35.191 1.00 26.49 ? 4222 HOH A O 1 HETATM 7335 O O . HOH Q 6 . ? -21.951 34.789 7.851 1.00 33.68 ? 4223 HOH A O 1 HETATM 7336 O O . HOH Q 6 . ? -44.242 6.070 -32.763 1.00 25.70 ? 4224 HOH A O 1 HETATM 7337 O O . HOH Q 6 . ? -42.326 -1.614 -48.248 1.00 28.95 ? 4225 HOH A O 1 HETATM 7338 O O . HOH Q 6 . ? -58.856 10.125 -7.124 1.00 30.89 ? 4226 HOH A O 1 HETATM 7339 O O . HOH Q 6 . ? -24.439 2.090 -0.756 1.00 28.24 ? 4227 HOH A O 1 HETATM 7340 O O . HOH Q 6 . ? -28.520 -19.809 -29.571 1.00 34.26 ? 4228 HOH A O 1 HETATM 7341 O O . HOH Q 6 . ? -25.923 11.519 -30.093 1.00 25.90 ? 4229 HOH A O 1 HETATM 7342 O O . HOH Q 6 . ? -46.183 8.008 -51.663 1.00 31.41 ? 4230 HOH A O 1 HETATM 7343 O O . HOH Q 6 . ? -42.800 19.687 -24.911 1.00 28.08 ? 4231 HOH A O 1 HETATM 7344 O O . HOH Q 6 . ? -24.146 9.693 -30.110 1.00 26.05 ? 4232 HOH A O 1 HETATM 7345 O O . HOH Q 6 . ? -10.959 -12.329 -8.340 1.00 32.24 ? 4233 HOH A O 1 HETATM 7346 O O . HOH Q 6 . ? -36.684 14.109 -39.571 1.00 37.53 ? 4234 HOH A O 1 HETATM 7347 O O . HOH Q 6 . ? -47.695 14.365 -26.322 1.00 30.29 ? 4235 HOH A O 1 HETATM 7348 O O . HOH Q 6 . ? -23.298 23.112 20.358 1.00 28.75 ? 4236 HOH A O 1 HETATM 7349 O O . HOH Q 6 . ? -37.126 12.431 -48.375 1.00 33.89 ? 4237 HOH A O 1 HETATM 7350 O O . HOH Q 6 . ? -44.675 -6.772 -44.364 1.00 35.20 ? 4238 HOH A O 1 HETATM 7351 O O . HOH Q 6 . ? 2.013 10.308 3.886 1.00 36.62 ? 4239 HOH A O 1 HETATM 7352 O O . HOH Q 6 . ? -17.078 22.962 -20.789 1.00 26.64 ? 4240 HOH A O 1 HETATM 7353 O O . HOH Q 6 . ? -40.011 18.364 -0.110 1.00 33.83 ? 4241 HOH A O 1 HETATM 7354 O O . HOH Q 6 . ? -40.518 35.384 -22.947 1.00 34.89 ? 4242 HOH A O 1 HETATM 7355 O O . HOH Q 6 . ? -15.400 8.518 -29.145 1.00 34.26 ? 4243 HOH A O 1 HETATM 7356 O O . HOH Q 6 . ? -49.190 -12.939 -18.330 1.00 30.81 ? 4244 HOH A O 1 HETATM 7357 O O . HOH Q 6 . ? -38.160 -5.186 0.591 1.00 27.73 ? 4245 HOH A O 1 HETATM 7358 O O . HOH Q 6 . ? -4.031 9.530 2.992 1.00 30.22 ? 4246 HOH A O 1 HETATM 7359 O O . HOH Q 6 . ? -48.883 5.474 -8.909 1.00 29.20 ? 4247 HOH A O 1 HETATM 7360 O O . HOH Q 6 . ? -46.454 25.628 -20.426 1.00 33.64 ? 4248 HOH A O 1 HETATM 7361 O O . HOH Q 6 . ? -33.072 10.706 -22.663 1.00 21.30 ? 4249 HOH A O 1 HETATM 7362 O O . HOH Q 6 . ? -19.296 26.393 21.891 1.00 28.44 ? 4250 HOH A O 1 HETATM 7363 O O . HOH Q 6 . ? -64.412 0.151 -24.923 1.00 29.67 ? 4251 HOH A O 1 HETATM 7364 O O . HOH Q 6 . ? -41.182 -12.265 -1.905 1.00 32.92 ? 4252 HOH A O 1 HETATM 7365 O O . HOH Q 6 . ? -35.519 12.555 -2.491 1.00 26.90 ? 4253 HOH A O 1 HETATM 7366 O O . HOH Q 6 . ? -14.479 41.431 -19.907 1.00 34.60 ? 4254 HOH A O 1 HETATM 7367 O O . HOH Q 6 . ? -14.699 5.743 -5.631 1.00 31.11 ? 4255 HOH A O 1 HETATM 7368 O O . HOH Q 6 . ? -50.310 -3.042 -4.252 1.00 31.56 ? 4256 HOH A O 1 HETATM 7369 O O . HOH Q 6 . ? -30.759 32.881 3.999 1.00 27.04 ? 4257 HOH A O 1 HETATM 7370 O O . HOH Q 6 . ? -46.870 18.895 -23.336 1.00 31.55 ? 4258 HOH A O 1 HETATM 7371 O O . HOH Q 6 . ? -54.600 13.230 -23.724 1.00 25.55 ? 4259 HOH A O 1 HETATM 7372 O O . HOH Q 6 . ? -7.683 35.814 -6.728 1.00 30.79 ? 4260 HOH A O 1 HETATM 7373 O O . HOH Q 6 . ? -37.694 10.524 -17.581 1.00 32.91 ? 4261 HOH A O 1 HETATM 7374 O O . HOH Q 6 . ? -33.438 38.726 -12.854 1.00 34.57 ? 4262 HOH A O 1 HETATM 7375 O O . HOH Q 6 . ? -6.989 -1.135 1.259 1.00 30.05 ? 4263 HOH A O 1 HETATM 7376 O O . HOH Q 6 . ? -0.510 8.712 -2.545 1.00 31.89 ? 4264 HOH A O 1 HETATM 7377 O O . HOH Q 6 . ? -43.475 30.999 -22.173 1.00 32.78 ? 4265 HOH A O 1 HETATM 7378 O O . HOH Q 6 . ? -49.526 2.471 -8.952 1.00 31.79 ? 4266 HOH A O 1 HETATM 7379 O O . HOH Q 6 . ? -42.989 2.421 -4.923 1.00 40.23 ? 4267 HOH A O 1 HETATM 7380 O O . HOH Q 6 . ? -37.202 -24.434 -21.798 1.00 27.88 ? 4268 HOH A O 1 HETATM 7381 O O . HOH Q 6 . ? -50.236 24.783 -19.875 1.00 33.61 ? 4269 HOH A O 1 HETATM 7382 O O . HOH Q 6 . ? -1.420 9.010 -20.096 1.00 27.70 ? 4270 HOH A O 1 HETATM 7383 O O . HOH Q 6 . ? -32.548 22.322 14.628 1.00 31.56 ? 4271 HOH A O 1 HETATM 7384 O O . HOH Q 6 . ? -19.310 15.837 5.261 1.00 32.12 ? 4272 HOH A O 1 HETATM 7385 O O . HOH Q 6 . ? -57.683 -2.248 -17.800 1.00 32.97 ? 4273 HOH A O 1 HETATM 7386 O O . HOH Q 6 . ? -30.247 26.005 -29.025 1.00 33.90 ? 4274 HOH A O 1 HETATM 7387 O O . HOH Q 6 . ? -20.031 -27.456 -16.744 1.00 37.39 ? 4275 HOH A O 1 HETATM 7388 O O . HOH Q 6 . ? -11.888 -9.064 -22.614 1.00 28.92 ? 4276 HOH A O 1 HETATM 7389 O O . HOH Q 6 . ? -21.350 4.583 -28.824 1.00 30.35 ? 4277 HOH A O 1 HETATM 7390 O O . HOH Q 6 . ? 3.198 3.170 -8.217 1.00 40.27 ? 4278 HOH A O 1 HETATM 7391 O O . HOH Q 6 . ? -18.871 16.005 -9.808 1.00 35.91 ? 4279 HOH A O 1 HETATM 7392 O O . HOH Q 6 . ? -54.122 -2.318 -49.521 1.00 32.66 ? 4280 HOH A O 1 HETATM 7393 O O . HOH Q 6 . ? -30.317 -22.803 -9.370 1.00 35.58 ? 4281 HOH A O 1 HETATM 7394 O O . HOH Q 6 . ? -30.101 -15.691 -1.008 1.00 35.12 ? 4282 HOH A O 1 HETATM 7395 O O . HOH Q 6 . ? -3.097 -11.047 -25.941 1.00 37.50 ? 4283 HOH A O 1 HETATM 7396 O O . HOH Q 6 . ? -6.530 34.751 -3.977 1.00 32.76 ? 4284 HOH A O 1 HETATM 7397 O O . HOH Q 6 . ? -33.525 23.110 17.858 1.00 35.55 ? 4285 HOH A O 1 HETATM 7398 O O . HOH Q 6 . ? -58.791 16.111 -30.742 1.00 34.40 ? 4286 HOH A O 1 HETATM 7399 O O . HOH Q 6 . ? -22.014 -0.830 -0.409 1.00 37.18 ? 4287 HOH A O 1 HETATM 7400 O O . HOH Q 6 . ? -27.671 25.325 -28.786 1.00 31.00 ? 4288 HOH A O 1 HETATM 7401 O O . HOH Q 6 . ? -53.791 -8.170 -43.691 1.00 33.24 ? 4289 HOH A O 1 HETATM 7402 O O . HOH Q 6 . ? -12.082 16.354 5.409 1.00 40.57 ? 4290 HOH A O 1 HETATM 7403 O O . HOH Q 6 . ? -15.149 -19.250 -13.249 1.00 34.81 ? 4291 HOH A O 1 HETATM 7404 O O . HOH Q 6 . ? -31.663 -26.900 -18.177 1.00 35.14 ? 4292 HOH A O 1 HETATM 7405 O O . HOH Q 6 . ? -18.123 0.597 2.677 1.00 46.24 ? 4293 HOH A O 1 HETATM 7406 O O . HOH Q 6 . ? -23.859 -10.085 -35.186 1.00 47.92 ? 4294 HOH A O 1 HETATM 7407 O O . HOH Q 6 . ? -64.769 3.056 -26.370 1.00 32.47 ? 4295 HOH A O 1 HETATM 7408 O O . HOH Q 6 . ? -60.883 -6.868 -31.323 1.00 33.03 ? 4296 HOH A O 1 HETATM 7409 O O . HOH Q 6 . ? -31.989 0.180 -8.131 1.00 30.41 ? 4297 HOH A O 1 HETATM 7410 O O . HOH Q 6 . ? -0.640 -1.902 -29.091 1.00 32.30 ? 4298 HOH A O 1 HETATM 7411 O O . HOH Q 6 . ? 4.345 0.057 -11.568 1.00 37.09 ? 4299 HOH A O 1 HETATM 7412 O O . HOH Q 6 . ? -25.012 35.123 -3.742 1.00 33.14 ? 4300 HOH A O 1 HETATM 7413 O O . HOH Q 6 . ? -7.873 1.954 3.800 1.00 34.20 ? 4301 HOH A O 1 HETATM 7414 O O . HOH Q 6 . ? 3.353 -2.747 -12.815 1.00 35.78 ? 4302 HOH A O 1 HETATM 7415 O O . HOH Q 6 . ? -24.615 34.828 16.594 1.00 33.98 ? 4303 HOH A O 1 HETATM 7416 O O . HOH Q 6 . ? -3.589 5.334 3.080 1.00 38.96 ? 4304 HOH A O 1 HETATM 7417 O O . HOH Q 6 . ? -15.743 -22.800 -12.934 1.00 36.82 ? 4305 HOH A O 1 HETATM 7418 O O . HOH Q 6 . ? -56.351 -3.697 -15.577 1.00 44.13 ? 4306 HOH A O 1 HETATM 7419 O O . HOH Q 6 . ? -8.995 12.808 5.407 1.00 31.88 ? 4307 HOH A O 1 HETATM 7420 O O . HOH Q 6 . ? -39.784 0.753 -1.143 1.00 36.42 ? 4308 HOH A O 1 HETATM 7421 O O . HOH Q 6 . ? -30.634 -2.184 -45.388 1.00 37.43 ? 4309 HOH A O 1 HETATM 7422 O O . HOH Q 6 . ? -23.296 3.473 -30.118 1.00 34.10 ? 4310 HOH A O 1 HETATM 7423 O O . HOH Q 6 . ? -27.332 40.119 -2.832 1.00 41.88 ? 4311 HOH A O 1 HETATM 7424 O O . HOH Q 6 . ? -51.504 10.684 -7.139 1.00 37.20 ? 4312 HOH A O 1 HETATM 7425 O O . HOH Q 6 . ? -33.450 28.290 -27.600 1.00 31.84 ? 4313 HOH A O 1 HETATM 7426 O O . HOH Q 6 . ? -12.162 16.222 -24.421 1.00 33.30 ? 4314 HOH A O 1 HETATM 7427 O O . HOH Q 6 . ? -14.116 20.493 9.737 1.00 39.83 ? 4315 HOH A O 1 HETATM 7428 O O . HOH Q 6 . ? -30.007 35.113 -31.564 1.00 35.04 ? 4316 HOH A O 1 HETATM 7429 O O . HOH Q 6 . ? -10.272 30.421 11.405 1.00 44.52 ? 4317 HOH A O 1 HETATM 7430 O O . HOH Q 6 . ? -35.926 12.149 -5.267 1.00 28.94 ? 4318 HOH A O 1 HETATM 7431 O O . HOH Q 6 . ? -49.321 -7.246 -37.840 1.00 44.90 ? 4319 HOH A O 1 HETATM 7432 O O . HOH Q 6 . ? -49.931 -0.153 -52.130 1.00 34.09 ? 4320 HOH A O 1 HETATM 7433 O O . HOH Q 6 . ? -34.126 39.686 -20.767 1.00 35.59 ? 4321 HOH A O 1 HETATM 7434 O O . HOH Q 6 . ? -19.147 -8.824 -34.812 1.00 33.89 ? 4322 HOH A O 1 HETATM 7435 O O . HOH Q 6 . ? -37.378 20.144 10.589 1.00 40.66 ? 4323 HOH A O 1 HETATM 7436 O O . HOH Q 6 . ? -49.427 -7.505 -28.484 1.00 30.80 ? 4324 HOH A O 1 HETATM 7437 O O . HOH Q 6 . ? -11.670 -1.794 -39.179 1.00 41.75 ? 4325 HOH A O 1 HETATM 7438 O O . HOH Q 6 . ? -53.382 -4.971 -29.207 1.00 43.59 ? 4326 HOH A O 1 HETATM 7439 O O . HOH Q 6 . ? -1.659 -10.310 -7.815 1.00 33.33 ? 4327 HOH A O 1 HETATM 7440 O O . HOH Q 6 . ? -7.571 -18.968 -24.937 1.00 38.40 ? 4328 HOH A O 1 HETATM 7441 O O . HOH Q 6 . ? -35.658 0.432 -38.193 1.00 26.01 ? 4329 HOH A O 1 HETATM 7442 O O . HOH Q 6 . ? -28.147 11.019 1.436 1.00 38.20 ? 4330 HOH A O 1 HETATM 7443 O O . HOH Q 6 . ? -39.782 32.060 -7.545 1.00 33.96 ? 4331 HOH A O 1 HETATM 7444 O O . HOH Q 6 . ? 4.785 7.959 -6.667 1.00 52.63 ? 4332 HOH A O 1 HETATM 7445 O O . HOH Q 6 . ? -33.938 39.658 -25.481 1.00 33.25 ? 4333 HOH A O 1 HETATM 7446 O O . HOH Q 6 . ? -0.065 8.160 -5.883 1.00 32.48 ? 4334 HOH A O 1 HETATM 7447 O O . HOH Q 6 . ? -50.491 12.238 -41.434 1.00 30.58 ? 4335 HOH A O 1 HETATM 7448 O O . HOH Q 6 . ? -34.367 4.310 3.961 1.00 45.00 ? 4336 HOH A O 1 HETATM 7449 O O . HOH Q 6 . ? -30.697 -26.426 -21.780 1.00 31.79 ? 4337 HOH A O 1 HETATM 7450 O O . HOH Q 6 . ? -16.597 -25.923 -23.350 1.00 33.02 ? 4338 HOH A O 1 HETATM 7451 O O . HOH Q 6 . ? -51.160 27.375 -12.398 1.00 37.26 ? 4339 HOH A O 1 HETATM 7452 O O . HOH Q 6 . ? -58.140 -8.554 -27.969 1.00 42.25 ? 4340 HOH A O 1 HETATM 7453 O O . HOH Q 6 . ? 2.076 -7.467 -29.102 1.00 41.20 ? 4341 HOH A O 1 HETATM 7454 O O . HOH Q 6 . ? -69.777 -6.235 -37.334 1.00 38.36 ? 4342 HOH A O 1 HETATM 7455 O O . HOH Q 6 . ? -48.182 0.268 -6.838 1.00 41.90 ? 4343 HOH A O 1 HETATM 7456 O O . HOH Q 6 . ? -67.807 -2.015 -44.422 1.00 42.89 ? 4344 HOH A O 1 HETATM 7457 O O . HOH Q 6 . ? -38.482 1.346 -45.233 1.00 33.59 ? 4345 HOH A O 1 HETATM 7458 O O . HOH Q 6 . ? -19.404 -26.780 -31.470 1.00 36.99 ? 4346 HOH A O 1 HETATM 7459 O O . HOH Q 6 . ? -14.519 -27.476 -17.625 1.00 38.98 ? 4347 HOH A O 1 HETATM 7460 O O . HOH Q 6 . ? 5.212 1.852 -18.468 1.00 48.95 ? 4348 HOH A O 1 HETATM 7461 O O . HOH Q 6 . ? -6.478 -1.250 -38.063 1.00 37.87 ? 4349 HOH A O 1 HETATM 7462 O O . HOH Q 6 . ? -22.827 6.897 4.008 1.00 38.78 ? 4350 HOH A O 1 HETATM 7463 O O . HOH Q 6 . ? -14.182 35.755 -19.093 1.00 33.01 ? 4351 HOH A O 1 HETATM 7464 O O . HOH Q 6 . ? -20.200 29.051 -30.149 1.00 51.06 ? 4352 HOH A O 1 HETATM 7465 O O . HOH Q 6 . ? -3.469 10.212 6.424 1.00 32.85 ? 4353 HOH A O 1 HETATM 7466 O O . HOH Q 6 . ? -14.873 31.325 19.162 1.00 37.91 ? 4354 HOH A O 1 HETATM 7467 O O . HOH Q 6 . ? -39.184 -27.476 -16.935 1.00 38.36 ? 4355 HOH A O 1 HETATM 7468 O O . HOH Q 6 . ? -26.195 40.443 -29.417 1.00 42.46 ? 4356 HOH A O 1 HETATM 7469 O O . HOH Q 6 . ? -39.120 28.663 -24.573 1.00 31.93 ? 4357 HOH A O 1 HETATM 7470 O O . HOH Q 6 . ? -42.986 11.572 -3.917 1.00 49.43 ? 4358 HOH A O 1 HETATM 7471 O O . HOH Q 6 . ? -55.232 14.315 -36.121 1.00 43.01 ? 4359 HOH A O 1 HETATM 7472 O O . HOH Q 6 . ? -39.572 18.334 -33.951 1.00 40.72 ? 4360 HOH A O 1 HETATM 7473 O O . HOH Q 6 . ? -18.231 35.787 -27.589 1.00 37.51 ? 4361 HOH A O 1 HETATM 7474 O O . HOH Q 6 . ? -23.825 42.211 -23.727 1.00 36.54 ? 4362 HOH A O 1 HETATM 7475 O O . HOH Q 6 . ? -28.319 20.164 14.568 1.00 42.26 ? 4363 HOH A O 1 HETATM 7476 O O . HOH Q 6 . ? -31.909 -3.248 -0.681 1.00 50.43 ? 4364 HOH A O 1 HETATM 7477 O O . HOH Q 6 . ? -37.282 30.418 -27.052 1.00 32.00 ? 4365 HOH A O 1 HETATM 7478 O O . HOH Q 6 . ? -11.289 8.711 -23.798 1.00 40.74 ? 4366 HOH A O 1 HETATM 7479 O O . HOH Q 6 . ? -20.664 35.878 14.477 1.00 39.27 ? 4367 HOH A O 1 HETATM 7480 O O . HOH Q 6 . ? -26.485 45.042 -3.741 1.00 35.78 ? 4368 HOH A O 1 HETATM 7481 O O . HOH Q 6 . ? -29.601 15.512 -38.843 1.00 43.89 ? 4369 HOH A O 1 HETATM 7482 O O . HOH Q 6 . ? 4.280 -0.391 -17.085 1.00 43.88 ? 4370 HOH A O 1 HETATM 7483 O O . HOH Q 6 . ? -55.417 13.723 -31.129 1.00 36.47 ? 4371 HOH A O 1 HETATM 7484 O O . HOH Q 6 . ? -23.634 -17.116 -3.385 1.00 44.37 ? 4372 HOH A O 1 HETATM 7485 O O . HOH Q 6 . ? -30.567 -4.063 -37.955 1.00 39.04 ? 4373 HOH A O 1 HETATM 7486 O O . HOH Q 6 . ? -48.373 -6.156 -35.806 1.00 39.72 ? 4374 HOH A O 1 HETATM 7487 O O . HOH Q 6 . ? -8.525 4.199 -32.303 1.00 35.20 ? 4375 HOH A O 1 HETATM 7488 O O . HOH Q 6 . ? -12.741 43.553 -19.377 1.00 42.41 ? 4376 HOH A O 1 HETATM 7489 O O . HOH Q 6 . ? 1.632 -8.962 -10.426 1.00 37.05 ? 4377 HOH A O 1 HETATM 7490 O O . HOH Q 6 . ? -12.800 -28.192 -21.818 1.00 39.34 ? 4378 HOH A O 1 HETATM 7491 O O . HOH Q 6 . ? -36.460 31.736 -0.057 1.00 38.40 ? 4379 HOH A O 1 HETATM 7492 O O . HOH Q 6 . ? -31.569 7.344 -28.016 1.00 31.35 ? 4380 HOH A O 1 HETATM 7493 O O . HOH Q 6 . ? -30.269 -4.161 -35.034 1.00 29.09 ? 4381 HOH A O 1 HETATM 7494 O O . HOH Q 6 . ? -17.742 37.567 -25.443 1.00 34.19 ? 4382 HOH A O 1 HETATM 7495 O O . HOH Q 6 . ? -64.281 6.477 -35.808 1.00 44.06 ? 4383 HOH A O 1 HETATM 7496 O O . HOH Q 6 . ? -39.055 38.968 -10.268 1.00 40.86 ? 4384 HOH A O 1 HETATM 7497 O O . HOH Q 6 . ? -8.209 -9.815 -6.386 1.00 34.13 ? 4385 HOH A O 1 HETATM 7498 O O . HOH Q 6 . ? -12.654 -22.814 -31.573 1.00 45.30 ? 4386 HOH A O 1 HETATM 7499 O O . HOH Q 6 . ? -21.209 43.927 0.312 1.00 43.91 ? 4387 HOH A O 1 HETATM 7500 O O . HOH Q 6 . ? -13.492 46.299 -11.721 1.00 40.42 ? 4388 HOH A O 1 HETATM 7501 O O . HOH Q 6 . ? -40.628 -4.885 1.287 1.00 35.82 ? 4389 HOH A O 1 HETATM 7502 O O . HOH Q 6 . ? -41.956 -3.593 -50.848 1.00 45.38 ? 4390 HOH A O 1 HETATM 7503 O O . HOH Q 6 . ? -16.401 40.668 -26.372 1.00 35.95 ? 4391 HOH A O 1 HETATM 7504 O O . HOH Q 6 . ? -44.051 24.048 -4.604 1.00 35.61 ? 4392 HOH A O 1 HETATM 7505 O O . HOH Q 6 . ? -53.591 8.809 -50.649 1.00 48.26 ? 4393 HOH A O 1 HETATM 7506 O O . HOH Q 6 . ? -8.623 22.096 -16.905 1.00 34.82 ? 4394 HOH A O 1 HETATM 7507 O O . HOH Q 6 . ? -29.819 39.911 -8.061 1.00 38.82 ? 4395 HOH A O 1 HETATM 7508 O O . HOH Q 6 . ? -36.654 35.132 -4.962 1.00 40.26 ? 4396 HOH A O 1 HETATM 7509 O O . HOH Q 6 . ? -26.236 21.704 11.396 1.00 37.41 ? 4397 HOH A O 1 HETATM 7510 O O . HOH Q 6 . ? -26.067 6.429 -43.326 1.00 34.96 ? 4398 HOH A O 1 HETATM 7511 O O . HOH Q 6 . ? -60.014 7.621 -19.443 1.00 29.97 ? 4399 HOH A O 1 HETATM 7512 O O . HOH Q 6 . ? -5.287 28.336 -9.312 1.00 37.96 ? 4400 HOH A O 1 HETATM 7513 O O . HOH Q 6 . ? -16.790 -27.640 -18.843 1.00 40.78 ? 4401 HOH A O 1 HETATM 7514 O O . HOH Q 6 . ? -43.146 -8.873 -43.909 1.00 35.27 ? 4402 HOH A O 1 HETATM 7515 O O . HOH Q 6 . ? 3.454 -9.803 -25.565 1.00 44.09 ? 4403 HOH A O 1 HETATM 7516 O O . HOH Q 6 . ? 2.100 13.887 -0.462 1.00 35.78 ? 4404 HOH A O 1 HETATM 7517 O O . HOH Q 6 . ? -18.197 36.475 15.316 1.00 38.74 ? 4405 HOH A O 1 HETATM 7518 O O . HOH Q 6 . ? -37.860 39.248 -16.073 1.00 37.31 ? 4406 HOH A O 1 HETATM 7519 O O . HOH Q 6 . ? -53.356 -0.642 -51.135 1.00 49.31 ? 4407 HOH A O 1 HETATM 7520 O O . HOH Q 6 . ? -1.265 9.456 8.227 1.00 41.91 ? 4408 HOH A O 1 HETATM 7521 O O . HOH Q 6 . ? -9.579 -19.122 -30.216 1.00 32.81 ? 4409 HOH A O 1 HETATM 7522 O O . HOH Q 6 . ? -6.089 25.070 -8.509 1.00 44.20 ? 4410 HOH A O 1 HETATM 7523 O O . HOH Q 6 . ? -54.138 16.122 -19.815 1.00 36.38 ? 4411 HOH A O 1 HETATM 7524 O O . HOH Q 6 . ? -17.618 35.370 -22.635 1.00 36.22 ? 4412 HOH A O 1 HETATM 7525 O O . HOH Q 6 . ? -35.741 15.519 -37.497 1.00 46.73 ? 4413 HOH A O 1 HETATM 7526 O O . HOH Q 6 . ? -40.530 20.524 1.870 1.00 39.47 ? 4414 HOH A O 1 HETATM 7527 O O . HOH Q 6 . ? -20.795 17.965 -13.520 1.00 28.77 ? 4415 HOH A O 1 HETATM 7528 O O . HOH Q 6 . ? -33.802 22.379 -28.014 1.00 42.58 ? 4416 HOH A O 1 HETATM 7529 O O . HOH Q 6 . ? -6.936 -20.378 -21.034 1.00 41.59 ? 4417 HOH A O 1 HETATM 7530 O O . HOH Q 6 . ? -69.877 -6.370 -33.503 1.00 44.85 ? 4418 HOH A O 1 HETATM 7531 O O . HOH Q 6 . ? -10.579 -11.116 -6.162 1.00 42.18 ? 4419 HOH A O 1 HETATM 7532 O O . HOH Q 6 . ? -26.802 -23.258 -34.813 1.00 52.50 ? 4420 HOH A O 1 HETATM 7533 O O . HOH Q 6 . ? -9.144 -15.682 -11.080 1.00 40.64 ? 4421 HOH A O 1 HETATM 7534 O O . HOH Q 6 . ? -8.469 6.650 -31.905 1.00 49.69 ? 4422 HOH A O 1 HETATM 7535 O O . HOH Q 6 . ? -7.617 25.904 -17.012 1.00 50.67 ? 4423 HOH A O 1 HETATM 7536 O O . HOH Q 6 . ? -30.717 6.903 -48.988 1.00 39.38 ? 4424 HOH A O 1 HETATM 7537 O O . HOH Q 6 . ? -43.129 -26.095 -15.391 1.00 41.47 ? 4425 HOH A O 1 HETATM 7538 O O . HOH Q 6 . ? -57.108 -6.734 -19.453 1.00 43.49 ? 4426 HOH A O 1 HETATM 7539 O O . HOH Q 6 . ? -26.140 33.138 -29.316 1.00 29.53 ? 4427 HOH A O 1 HETATM 7540 O O . HOH Q 6 . ? -35.005 -14.309 -40.111 1.00 47.25 ? 4428 HOH A O 1 HETATM 7541 O O . HOH Q 6 . ? -7.368 -22.212 -18.946 1.00 48.85 ? 4429 HOH A O 1 HETATM 7542 O O . HOH Q 6 . ? -51.029 28.869 -14.180 1.00 53.17 ? 4430 HOH A O 1 HETATM 7543 O O . HOH Q 6 . ? -6.025 22.148 -5.252 1.00 43.11 ? 4431 HOH A O 1 HETATM 7544 O O . HOH Q 6 . ? -56.583 -3.002 -49.556 1.00 43.18 ? 4432 HOH A O 1 HETATM 7545 O O . HOH Q 6 . ? -28.492 -1.242 -44.698 1.00 41.48 ? 4433 HOH A O 1 HETATM 7546 O O . HOH Q 6 . ? -48.373 12.986 -36.708 1.00 36.05 ? 4434 HOH A O 1 HETATM 7547 O O . HOH Q 6 . ? -16.143 36.785 -29.810 1.00 41.35 ? 4435 HOH A O 1 HETATM 7548 O O . HOH Q 6 . ? -26.598 4.300 -44.439 1.00 41.77 ? 4436 HOH A O 1 HETATM 7549 O O . HOH Q 6 . ? -11.553 -23.055 -27.836 1.00 37.83 ? 4437 HOH A O 1 HETATM 7550 O O . HOH Q 6 . ? -59.101 -3.297 -12.875 1.00 41.50 ? 4438 HOH A O 1 HETATM 7551 O O . HOH Q 6 . ? -14.516 31.524 -26.525 1.00 49.66 ? 4439 HOH A O 1 HETATM 7552 O O . HOH Q 6 . ? -40.771 28.877 -3.705 1.00 37.90 ? 4440 HOH A O 1 HETATM 7553 O O . HOH Q 6 . ? -55.349 17.451 -9.835 1.00 43.02 ? 4441 HOH A O 1 HETATM 7554 O O . HOH Q 6 . ? -8.969 15.426 5.693 1.00 41.48 ? 4442 HOH A O 1 HETATM 7555 O O . HOH Q 6 . ? -42.149 -6.965 1.048 1.00 35.20 ? 4443 HOH A O 1 HETATM 7556 O O . HOH Q 6 . ? -30.974 -4.013 -41.422 1.00 40.63 ? 4444 HOH A O 1 HETATM 7557 O O . HOH Q 6 . ? -23.550 -22.149 -12.695 1.00 41.28 ? 4445 HOH A O 1 HETATM 7558 O O . HOH Q 6 . ? -45.657 -3.688 0.534 1.00 41.15 ? 4446 HOH A O 1 HETATM 7559 O O . HOH Q 6 . ? -26.812 -21.809 -10.200 1.00 47.93 ? 4447 HOH A O 1 HETATM 7560 O O . HOH Q 6 . ? -56.805 -6.918 -30.616 1.00 41.38 ? 4448 HOH A O 1 HETATM 7561 O O . HOH Q 6 . ? -42.872 25.958 -27.530 1.00 49.51 ? 4449 HOH A O 1 HETATM 7562 O O . HOH Q 6 . ? -19.251 -12.028 -5.629 1.00 44.17 ? 4450 HOH A O 1 HETATM 7563 O O . HOH Q 6 . ? -0.441 18.814 0.747 1.00 41.79 ? 4451 HOH A O 1 HETATM 7564 O O . HOH Q 6 . ? -55.385 -13.184 -15.147 1.00 41.38 ? 4452 HOH A O 1 HETATM 7565 O O . HOH Q 6 . ? -14.641 -13.450 -5.975 1.00 44.89 ? 4453 HOH A O 1 HETATM 7566 O O . HOH Q 6 . ? -33.303 -26.903 -23.261 1.00 38.93 ? 4454 HOH A O 1 HETATM 7567 O O . HOH Q 6 . ? -35.459 10.456 -0.732 1.00 38.68 ? 4455 HOH A O 1 HETATM 7568 O O . HOH Q 6 . ? -9.917 -5.925 -13.634 1.00 35.68 ? 4456 HOH A O 1 HETATM 7569 O O . HOH Q 6 . ? 10.224 -15.594 -17.587 1.00 49.05 ? 4457 HOH A O 1 HETATM 7570 O O . HOH Q 6 . ? -52.892 26.910 -14.181 1.00 40.33 ? 4458 HOH A O 1 HETATM 7571 O O . HOH Q 6 . ? -16.367 2.775 -38.432 1.00 42.80 ? 4459 HOH A O 1 HETATM 7572 O O . HOH Q 6 . ? -26.588 4.818 -47.089 1.00 42.58 ? 4460 HOH A O 1 HETATM 7573 O O . HOH Q 6 . ? -17.448 49.122 -6.272 1.00 41.16 ? 4461 HOH A O 1 HETATM 7574 O O . HOH Q 6 . ? -60.715 -6.284 -52.744 1.00 50.31 ? 4462 HOH A O 1 HETATM 7575 O O . HOH Q 6 . ? -60.318 -5.026 -20.332 1.00 39.80 ? 4463 HOH A O 1 HETATM 7576 O O . HOH Q 6 . ? -16.506 -19.483 -38.155 1.00 46.83 ? 4464 HOH A O 1 HETATM 7577 O O . HOH Q 6 . ? -21.546 16.969 4.735 1.00 40.69 ? 4465 HOH A O 1 HETATM 7578 O O . HOH Q 6 . ? -26.849 36.646 -31.850 1.00 48.34 ? 4466 HOH A O 1 HETATM 7579 O O . HOH Q 6 . ? -17.331 31.989 21.138 1.00 45.99 ? 4467 HOH A O 1 HETATM 7580 O O . HOH Q 6 . ? -70.122 8.941 -41.205 1.00 49.55 ? 4468 HOH A O 1 HETATM 7581 O O . HOH Q 6 . ? -14.188 16.802 -28.297 1.00 38.73 ? 4469 HOH A O 1 HETATM 7582 O O . HOH Q 6 . ? -5.057 0.825 -32.651 1.00 40.14 ? 4470 HOH A O 1 HETATM 7583 O O . HOH Q 6 . ? -36.191 -23.109 -31.011 1.00 48.20 ? 4471 HOH A O 1 HETATM 7584 O O . HOH Q 6 . ? -53.502 -7.588 -27.578 1.00 52.41 ? 4472 HOH A O 1 HETATM 7585 O O . HOH Q 6 . ? -22.049 -3.578 -3.917 1.00 36.32 ? 4473 HOH A O 1 HETATM 7586 O O . HOH Q 6 . ? -50.524 15.554 -45.868 1.00 55.37 ? 4474 HOH A O 1 HETATM 7587 O O . HOH Q 6 . ? -31.710 -0.514 -48.870 1.00 47.83 ? 4475 HOH A O 1 HETATM 7588 O O . HOH Q 6 . ? -17.999 8.426 7.042 1.00 47.76 ? 4476 HOH A O 1 HETATM 7589 O O . HOH Q 6 . ? -27.115 28.892 22.855 1.00 37.21 ? 4477 HOH A O 1 HETATM 7590 O O . HOH Q 6 . ? -45.914 24.803 -7.951 1.00 40.40 ? 4478 HOH A O 1 HETATM 7591 O O . HOH Q 6 . ? -53.122 13.731 -30.109 1.00 33.48 ? 4479 HOH A O 1 HETATM 7592 O O . HOH Q 6 . ? -36.605 25.142 -24.582 1.00 41.75 ? 4480 HOH A O 1 HETATM 7593 O O . HOH Q 6 . ? -46.355 13.586 -35.073 1.00 57.58 ? 4481 HOH A O 1 HETATM 7594 O O . HOH Q 6 . ? -47.009 -19.505 -9.649 1.00 50.38 ? 4482 HOH A O 1 HETATM 7595 O O . HOH Q 6 . ? -56.769 12.595 -41.398 1.00 37.73 ? 4483 HOH A O 1 HETATM 7596 O O . HOH Q 6 . ? -56.717 14.010 -9.306 1.00 39.29 ? 4484 HOH A O 1 HETATM 7597 O O . HOH Q 6 . ? -10.550 7.487 10.887 1.00 40.36 ? 4485 HOH A O 1 HETATM 7598 O O . HOH Q 6 . ? -35.016 40.274 -29.335 1.00 39.36 ? 4486 HOH A O 1 HETATM 7599 O O . HOH Q 6 . ? -12.623 -21.503 -13.257 1.00 38.49 ? 4487 HOH A O 1 HETATM 7600 O O . HOH Q 6 . ? -37.875 -10.937 -46.015 1.00 51.64 ? 4488 HOH A O 1 HETATM 7601 O O . HOH Q 6 . ? -2.556 29.461 -7.901 1.00 49.90 ? 4489 HOH A O 1 HETATM 7602 O O . HOH Q 6 . ? -48.965 -10.431 -38.712 1.00 47.00 ? 4490 HOH A O 1 HETATM 7603 O O . HOH Q 6 . ? -50.506 14.492 -30.748 1.00 48.10 ? 4491 HOH A O 1 HETATM 7604 O O . HOH Q 6 . ? -34.377 -2.909 1.667 1.00 38.16 ? 4492 HOH A O 1 HETATM 7605 O O . HOH Q 6 . ? -25.462 31.092 23.887 1.00 49.73 ? 4493 HOH A O 1 HETATM 7606 O O . HOH Q 6 . ? -46.944 -13.368 -1.231 1.00 36.64 ? 4494 HOH A O 1 HETATM 7607 O O . HOH Q 6 . ? -40.614 3.596 -2.845 1.00 48.00 ? 4495 HOH A O 1 HETATM 7608 O O . HOH Q 6 . ? -43.561 -27.339 -22.044 1.00 46.68 ? 4496 HOH A O 1 HETATM 7609 O O . HOH Q 6 . ? -21.673 21.050 -28.979 1.00 30.75 ? 4497 HOH A O 1 HETATM 7610 O O . HOH Q 6 . ? -70.266 -1.377 -24.981 1.00 40.05 ? 4498 HOH A O 1 HETATM 7611 O O . HOH Q 6 . ? -20.687 6.876 -30.170 1.00 49.46 ? 4499 HOH A O 1 HETATM 7612 O O . HOH Q 6 . ? -10.964 -17.927 -32.555 1.00 43.50 ? 4500 HOH A O 1 HETATM 7613 O O . HOH Q 6 . ? -47.821 17.842 -5.188 1.00 49.57 ? 4501 HOH A O 1 HETATM 7614 O O . HOH Q 6 . ? 7.207 -9.877 -21.579 1.00 44.87 ? 4502 HOH A O 1 HETATM 7615 O O . HOH Q 6 . ? -37.492 36.268 10.163 1.00 53.57 ? 4503 HOH A O 1 HETATM 7616 O O . HOH Q 6 . ? -61.031 1.710 -8.089 1.00 40.04 ? 4504 HOH A O 1 HETATM 7617 O O . HOH Q 6 . ? -24.307 -21.047 -10.279 1.00 43.73 ? 4505 HOH A O 1 HETATM 7618 O O . HOH Q 6 . ? -29.547 29.261 23.182 1.00 48.98 ? 4506 HOH A O 1 HETATM 7619 O O . HOH Q 6 . ? -49.417 -21.638 -15.976 1.00 46.37 ? 4507 HOH A O 1 HETATM 7620 O O . HOH Q 6 . ? -31.346 -6.608 -37.926 1.00 39.74 ? 4508 HOH A O 1 HETATM 7621 O O . HOH Q 6 . ? -56.941 -14.264 -12.957 1.00 41.44 ? 4509 HOH A O 1 HETATM 7622 O O . HOH Q 6 . ? 1.366 -14.015 -17.269 1.00 36.23 ? 4510 HOH A O 1 HETATM 7623 O O . HOH Q 6 . ? -37.557 -24.587 -18.896 1.00 37.01 ? 4511 HOH A O 1 HETATM 7624 O O . HOH Q 6 . ? -29.479 13.948 4.091 1.00 38.73 ? 4512 HOH A O 1 HETATM 7625 O O . HOH Q 6 . ? -62.066 8.316 -36.147 1.00 40.08 ? 4513 HOH A O 1 HETATM 7626 O O . HOH Q 6 . ? -24.847 26.579 -29.328 1.00 66.53 ? 4514 HOH A O 1 HETATM 7627 O O . HOH Q 6 . ? 1.020 7.975 -24.519 1.00 42.65 ? 4515 HOH A O 1 HETATM 7628 O O . HOH Q 6 . ? -43.550 15.546 -33.359 1.00 50.92 ? 4516 HOH A O 1 HETATM 7629 O O . HOH Q 6 . ? -57.184 -13.842 -10.557 1.00 45.16 ? 4517 HOH A O 1 HETATM 7630 O O . HOH Q 6 . ? 2.407 8.360 -22.330 1.00 38.69 ? 4518 HOH A O 1 HETATM 7631 O O . HOH Q 6 . ? -63.264 10.614 -21.554 1.00 34.90 ? 4519 HOH A O 1 HETATM 7632 O O . HOH Q 6 . ? -41.840 -12.579 -42.012 1.00 34.90 ? 4520 HOH A O 1 HETATM 7633 O O . HOH Q 6 . ? -48.807 -12.269 -40.851 1.00 49.21 ? 4521 HOH A O 1 HETATM 7634 O O . HOH Q 6 . ? -17.085 -6.151 -36.901 1.00 41.31 ? 4522 HOH A O 1 HETATM 7635 O O . HOH Q 6 . ? -39.347 30.118 2.962 1.00 41.39 ? 4523 HOH A O 1 HETATM 7636 O O . HOH Q 6 . ? -23.477 40.946 -28.876 1.00 34.90 ? 4524 HOH A O 1 HETATM 7637 O O . HOH Q 6 . ? -27.463 13.614 -36.104 1.00 55.22 ? 4525 HOH A O 1 HETATM 7638 O O . HOH Q 6 . ? 2.310 -2.278 -0.408 1.00 42.17 ? 4526 HOH A O 1 HETATM 7639 O O . HOH Q 6 . ? -7.880 18.763 -18.300 1.00 41.98 ? 4527 HOH A O 1 HETATM 7640 O O . HOH Q 6 . ? -13.752 27.357 12.129 1.00 41.16 ? 4528 HOH A O 1 HETATM 7641 O O . HOH Q 6 . ? -12.552 42.159 -15.634 1.00 53.55 ? 4529 HOH A O 1 HETATM 7642 O O . HOH Q 6 . ? -42.796 13.458 -31.912 1.00 48.07 ? 4530 HOH A O 1 HETATM 7643 O O . HOH Q 6 . ? -18.150 4.328 -37.134 1.00 46.68 ? 4531 HOH A O 1 HETATM 7644 O O . HOH Q 6 . ? -44.989 20.925 -5.275 1.00 35.63 ? 4532 HOH A O 1 HETATM 7645 O O . HOH Q 6 . ? -6.957 24.424 0.357 1.00 40.31 ? 4533 HOH A O 1 HETATM 7646 O O . HOH Q 6 . ? -13.025 28.549 3.328 1.00 41.79 ? 4534 HOH A O 1 HETATM 7647 O O . HOH Q 6 . ? -1.141 -12.416 -23.982 1.00 44.05 ? 4535 HOH A O 1 HETATM 7648 O O . HOH Q 6 . ? -66.320 -0.106 -23.702 1.00 39.69 ? 4536 HOH A O 1 HETATM 7649 O O . HOH Q 6 . ? -2.518 0.615 -33.052 1.00 46.33 ? 4537 HOH A O 1 HETATM 7650 O O . HOH Q 6 . ? -59.051 4.997 -59.807 1.00 46.60 ? 4538 HOH A O 1 HETATM 7651 O O . HOH Q 6 . ? -19.515 -4.795 -37.696 1.00 37.06 ? 4539 HOH A O 1 HETATM 7652 O O . HOH Q 6 . ? -71.437 2.185 -39.746 1.00 38.88 ? 4540 HOH A O 1 HETATM 7653 O O . HOH Q 6 . ? -48.304 29.878 -9.479 1.00 41.89 ? 4541 HOH A O 1 HETATM 7654 O O . HOH Q 6 . ? -50.505 -16.260 -9.395 1.00 47.84 ? 4542 HOH A O 1 HETATM 7655 O O . HOH Q 6 . ? -12.605 30.124 10.991 1.00 49.12 ? 4543 HOH A O 1 HETATM 7656 O O . HOH Q 6 . ? -25.773 -20.366 -28.626 1.00 42.03 ? 4544 HOH A O 1 HETATM 7657 O O . HOH Q 6 . ? -22.099 -14.371 -4.185 1.00 46.26 ? 4545 HOH A O 1 HETATM 7658 O O . HOH Q 6 . ? -23.016 36.890 -1.774 1.00 39.95 ? 4546 HOH A O 1 HETATM 7659 O O . HOH Q 6 . ? -50.091 28.871 -11.086 1.00 42.68 ? 4547 HOH A O 1 HETATM 7660 O O . HOH Q 6 . ? -33.334 -14.965 -36.151 1.00 46.21 ? 4548 HOH A O 1 HETATM 7661 O O . HOH Q 6 . ? -56.854 10.573 -57.754 1.00 48.39 ? 4549 HOH A O 1 HETATM 7662 O O . HOH Q 6 . ? -28.597 31.356 22.073 1.00 49.99 ? 4550 HOH A O 1 HETATM 7663 O O . HOH Q 6 . ? 8.007 -9.884 -15.090 1.00 53.79 ? 4551 HOH A O 1 HETATM 7664 O O . HOH Q 6 . ? -41.332 23.667 1.511 1.00 37.31 ? 4552 HOH A O 1 HETATM 7665 O O . HOH Q 6 . ? -48.323 -0.460 -54.588 1.00 59.42 ? 4553 HOH A O 1 HETATM 7666 O O . HOH Q 6 . ? -14.813 33.939 18.037 1.00 34.59 ? 4554 HOH A O 1 HETATM 7667 O O . HOH Q 6 . ? -10.058 41.136 -1.499 1.00 56.82 ? 4555 HOH A O 1 HETATM 7668 O O . HOH Q 6 . ? -13.946 19.278 7.448 1.00 45.19 ? 4556 HOH A O 1 HETATM 7669 O O . HOH Q 6 . ? -7.453 24.681 5.984 1.00 50.59 ? 4557 HOH A O 1 HETATM 7670 O O . HOH Q 6 . ? -12.618 34.319 16.999 1.00 35.40 ? 4558 HOH A O 1 HETATM 7671 O O . HOH Q 6 . ? -42.301 9.648 -31.297 1.00 39.45 ? 4559 HOH A O 1 HETATM 7672 O O . HOH Q 6 . ? 2.227 -14.635 -10.793 1.00 42.45 ? 4560 HOH A O 1 HETATM 7673 O O . HOH Q 6 . ? -37.543 17.775 8.606 1.00 41.39 ? 4561 HOH A O 1 HETATM 7674 O O . HOH Q 6 . ? -12.908 -17.566 -34.449 1.00 48.05 ? 4562 HOH A O 1 HETATM 7675 O O . HOH Q 6 . ? -8.231 8.036 -25.014 1.00 51.11 ? 4563 HOH A O 1 HETATM 7676 O O . HOH Q 6 . ? -40.176 -9.722 -45.166 1.00 47.34 ? 4564 HOH A O 1 HETATM 7677 O O . HOH Q 6 . ? -39.015 26.293 -25.328 1.00 43.95 ? 4565 HOH A O 1 HETATM 7678 O O . HOH Q 6 . ? -43.406 -13.910 -2.337 1.00 39.90 ? 4566 HOH A O 1 HETATM 7679 O O . HOH Q 6 . ? -56.332 14.544 -27.591 1.00 38.83 ? 4567 HOH A O 1 HETATM 7680 O O . HOH Q 6 . ? -24.268 6.910 -41.798 1.00 48.66 ? 4568 HOH A O 1 HETATM 7681 O O . HOH Q 6 . ? -49.927 -15.133 -19.579 1.00 44.47 ? 4569 HOH A O 1 HETATM 7682 O O . HOH Q 6 . ? 5.641 -6.147 -19.834 1.00 42.68 ? 4570 HOH A O 1 HETATM 7683 O O . HOH Q 6 . ? -10.310 9.101 -25.927 1.00 42.15 ? 4571 HOH A O 1 HETATM 7684 O O . HOH Q 6 . ? -6.261 3.172 -33.594 1.00 40.99 ? 4572 HOH A O 1 HETATM 7685 O O . HOH Q 6 . ? -17.359 16.548 7.202 1.00 43.01 ? 4573 HOH A O 1 HETATM 7686 O O . HOH Q 6 . ? -31.112 16.406 -34.757 1.00 33.99 ? 4574 HOH A O 1 HETATM 7687 O O . HOH Q 6 . ? -38.329 14.748 -41.827 1.00 50.33 ? 4575 HOH A O 1 HETATM 7688 O O . HOH Q 6 . ? 3.956 -7.541 -27.043 1.00 45.35 ? 4576 HOH A O 1 HETATM 7689 O O . HOH Q 6 . ? -47.728 11.970 -31.511 1.00 47.37 ? 4577 HOH A O 1 HETATM 7690 O O . HOH Q 6 . ? -34.548 -24.579 -29.409 1.00 45.22 ? 4578 HOH A O 1 HETATM 7691 O O . HOH Q 6 . ? -54.914 15.249 -33.304 1.00 52.39 ? 4579 HOH A O 1 HETATM 7692 O O . HOH Q 6 . ? -7.314 8.343 -29.973 1.00 44.23 ? 4580 HOH A O 1 HETATM 7693 O O . HOH Q 6 . ? -72.614 -1.332 -33.347 1.00 41.30 ? 4581 HOH A O 1 HETATM 7694 O O . HOH Q 6 . ? 2.403 -17.582 -10.060 1.00 52.19 ? 4582 HOH A O 1 HETATM 7695 O O . HOH Q 6 . ? -45.445 23.868 -25.284 1.00 54.21 ? 4583 HOH A O 1 HETATM 7696 O O . HOH Q 6 . ? -32.205 33.809 -30.130 1.00 42.05 ? 4584 HOH A O 1 HETATM 7697 O O . HOH Q 6 . ? -25.214 9.706 2.402 1.00 51.81 ? 4585 HOH A O 1 HETATM 7698 O O . HOH Q 6 . ? -28.307 14.533 -32.730 1.00 42.44 ? 4586 HOH A O 1 HETATM 7699 O O . HOH Q 6 . ? -23.322 34.912 -32.891 1.00 46.64 ? 4587 HOH A O 1 HETATM 7700 O O . HOH Q 6 . ? -38.847 4.158 -47.591 1.00 43.78 ? 4588 HOH A O 1 HETATM 7701 O O . HOH Q 6 . ? -44.651 -22.547 -21.612 1.00 42.59 ? 4589 HOH A O 1 HETATM 7702 O O . HOH Q 6 . ? -1.121 18.821 -3.147 1.00 63.17 ? 4590 HOH A O 1 HETATM 7703 O O . HOH Q 6 . ? -13.434 20.646 -23.508 1.00 34.54 ? 4591 HOH A O 1 HETATM 7704 O O . HOH Q 6 . ? -12.473 38.516 -18.736 1.00 38.50 ? 4592 HOH A O 1 HETATM 7705 O O . HOH Q 6 . ? -40.844 17.940 -3.025 1.00 47.77 ? 4593 HOH A O 1 HETATM 7706 O O . HOH Q 6 . ? -39.887 4.794 -49.772 1.00 43.10 ? 4594 HOH A O 1 HETATM 7707 O O . HOH Q 6 . ? -0.135 5.332 -5.892 1.00 53.38 ? 4595 HOH A O 1 HETATM 7708 O O . HOH Q 6 . ? -4.869 0.621 0.875 1.00 42.10 ? 4596 HOH A O 1 HETATM 7709 O O . HOH Q 6 . ? -72.262 -1.654 -26.784 1.00 51.15 ? 4597 HOH A O 1 HETATM 7710 O O . HOH Q 6 . ? -60.916 18.675 -33.646 1.00 52.29 ? 4598 HOH A O 1 HETATM 7711 O O . HOH Q 6 . ? -43.447 34.723 -8.884 1.00 42.21 ? 4599 HOH A O 1 HETATM 7712 O O . HOH Q 6 . ? -36.166 20.992 17.329 1.00 44.16 ? 4600 HOH A O 1 HETATM 7713 O O . HOH Q 6 . ? -42.225 14.738 -39.590 1.00 50.37 ? 4601 HOH A O 1 HETATM 7714 O O . HOH Q 6 . ? -12.874 -17.449 -13.452 1.00 41.47 ? 4602 HOH A O 1 HETATM 7715 O O . HOH Q 6 . ? -47.992 -12.589 -33.218 1.00 38.55 ? 4603 HOH A O 1 HETATM 7716 O O . HOH Q 6 . ? -20.073 -15.643 -35.859 1.00 32.54 ? 4604 HOH A O 1 HETATM 7717 O O . HOH Q 6 . ? -35.982 17.560 -34.132 1.00 48.83 ? 4605 HOH A O 1 HETATM 7718 O O . HOH Q 6 . ? -28.682 5.068 -49.344 1.00 45.41 ? 4606 HOH A O 1 HETATM 7719 O O . HOH Q 6 . ? -42.088 23.396 4.717 1.00 40.32 ? 4607 HOH A O 1 HETATM 7720 O O . HOH Q 6 . ? -18.121 16.190 -30.184 1.00 50.87 ? 4608 HOH A O 1 HETATM 7721 O O . HOH Q 6 . ? -14.267 -1.647 -4.737 1.00 45.33 ? 4609 HOH A O 1 HETATM 7722 O O . HOH Q 6 . ? -62.492 -7.336 -29.832 1.00 43.36 ? 4610 HOH A O 1 HETATM 7723 O O . HOH Q 6 . ? -27.689 42.796 -2.551 1.00 58.52 ? 4611 HOH A O 1 HETATM 7724 O O . HOH Q 6 . ? -36.512 22.723 -26.476 1.00 48.55 ? 4612 HOH A O 1 HETATM 7725 O O . HOH Q 6 . ? -15.279 47.100 -15.027 1.00 46.77 ? 4613 HOH A O 1 HETATM 7726 O O . HOH Q 6 . ? -55.769 18.635 -20.499 1.00 51.12 ? 4614 HOH A O 1 HETATM 7727 O O . HOH Q 6 . ? -35.619 -27.022 -22.079 1.00 49.03 ? 4615 HOH A O 1 HETATM 7728 O O . HOH Q 6 . ? -49.350 12.619 -48.494 1.00 46.51 ? 4616 HOH A O 1 HETATM 7729 O O . HOH Q 6 . ? -32.162 37.314 11.120 1.00 32.00 ? 4617 HOH A O 1 HETATM 7730 O O . HOH Q 6 . ? -14.804 -21.270 -14.760 1.00 22.19 ? 4618 HOH A O 1 HETATM 7731 O O . HOH Q 6 . ? -33.527 12.056 -24.384 1.00 31.84 ? 4619 HOH A O 1 HETATM 7732 O O . HOH Q 6 . ? -40.194 16.191 -37.635 1.00 43.49 ? 4620 HOH A O 1 HETATM 7733 O O . HOH Q 6 . ? -23.772 2.259 -27.442 1.00 27.67 ? 4621 HOH A O 1 HETATM 7734 O O . HOH Q 6 . ? 4.502 4.108 -17.988 1.00 35.90 ? 4622 HOH A O 1 HETATM 7735 O O . HOH Q 6 . ? -23.614 -10.715 -4.870 1.00 37.41 ? 4623 HOH A O 1 HETATM 7736 O O . HOH Q 6 . ? -22.547 -0.184 1.966 1.00 50.28 ? 4624 HOH A O 1 HETATM 7737 O O . HOH Q 6 . ? -19.594 -3.190 -3.608 1.00 34.99 ? 4625 HOH A O 1 HETATM 7738 O O . HOH Q 6 . ? -27.687 -3.600 1.091 1.00 31.66 ? 4626 HOH A O 1 HETATM 7739 O O . HOH Q 6 . ? -24.750 -5.700 -11.582 1.00 20.21 ? 4627 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 1 ? ? ? A . n A 1 2 ALA 2 2 ? ? ? A . n A 1 3 GLU 3 3 ? ? ? A . n A 1 4 CYS 4 4 ? ? ? A . n A 1 5 PRO 5 5 ? ? ? A . n A 1 6 VAL 6 6 ? ? ? A . n A 1 7 VAL 7 7 7 VAL VAL A . n A 1 8 ASN 8 8 8 ASN ASN A . n A 1 9 GLU 9 9 9 GLU GLU A . n A 1 10 LEU 10 10 10 LEU LEU A . n A 1 11 GLU 11 11 11 GLU GLU A . n A 1 12 ARG 12 12 12 ARG ARG A . n A 1 13 ILE 13 13 13 ILE ILE A . n A 1 14 ASN 14 14 14 ASN ASN A . n A 1 15 CYS 15 15 15 CYS CYS A . n A 1 16 ILE 16 16 16 ILE ILE A . n A 1 17 PRO 17 17 17 PRO PRO A . n A 1 18 ASP 18 18 18 ASP ASP A . n A 1 19 GLN 19 19 19 GLN GLN A . n A 1 20 PRO 20 20 20 PRO PRO A . n A 1 21 PRO 21 21 21 PRO PRO A . n A 1 22 THR 22 22 22 THR THR A . n A 1 23 LYS 23 23 23 LYS LYS A . n A 1 24 ALA 24 24 24 ALA ALA A . n A 1 25 THR 25 25 25 THR THR A . n A 1 26 CYS 26 26 26 CYS CYS A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 GLN 28 28 28 GLN GLN A . n A 1 29 ARG 29 29 29 ARG ARG A . n A 1 30 GLY 30 30 30 GLY GLY A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 CYS 32 32 32 CYS CYS A . n A 1 33 TRP 33 33 33 TRP TRP A . n A 1 34 ASN 34 34 34 ASN ASN A . n A 1 35 PRO 35 35 35 PRO PRO A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 GLY 37 37 37 GLY GLY A . n A 1 38 ALA 38 38 38 ALA ALA A . n A 1 39 VAL 39 39 39 VAL VAL A . n A 1 40 SER 40 40 40 SER SER A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 PRO 42 42 42 PRO PRO A . n A 1 43 TRP 43 43 43 TRP TRP A . n A 1 44 CYS 44 44 44 CYS CYS A . n A 1 45 TYR 45 45 45 TYR TYR A . n A 1 46 TYR 46 46 46 TYR TYR A . n A 1 47 SER 47 47 47 SER SER A . n A 1 48 LYS 48 48 48 LYS LYS A . n A 1 49 ASN 49 49 49 ASN ASN A . n A 1 50 HIS 50 50 50 HIS HIS A . n A 1 51 SER 51 51 51 SER SER A . n A 1 52 TYR 52 52 52 TYR TYR A . n A 1 53 HIS 53 53 53 HIS HIS A . n A 1 54 VAL 54 54 54 VAL VAL A . n A 1 55 GLU 55 55 55 GLU GLU A . n A 1 56 GLY 56 56 56 GLY GLY A . n A 1 57 ASN 57 57 57 ASN ASN A . n A 1 58 LEU 58 58 58 LEU LEU A . n A 1 59 VAL 59 59 59 VAL VAL A . n A 1 60 ASN 60 60 60 ASN ASN A . n A 1 61 THR 61 61 61 THR THR A . n A 1 62 ASN 62 62 62 ASN ASN A . n A 1 63 ALA 63 63 63 ALA ALA A . n A 1 64 GLY 64 64 64 GLY GLY A . n A 1 65 PHE 65 65 65 PHE PHE A . n A 1 66 THR 66 66 66 THR THR A . n A 1 67 ALA 67 67 67 ALA ALA A . n A 1 68 ARG 68 68 68 ARG ARG A . n A 1 69 LEU 69 69 69 LEU LEU A . n A 1 70 LYS 70 70 70 LYS LYS A . n A 1 71 ASN 71 71 71 ASN ASN A . n A 1 72 LEU 72 72 72 LEU LEU A . n A 1 73 PRO 73 73 73 PRO PRO A . n A 1 74 SER 74 74 74 SER SER A . n A 1 75 SER 75 75 75 SER SER A . n A 1 76 PRO 76 76 76 PRO PRO A . n A 1 77 VAL 77 77 77 VAL VAL A . n A 1 78 PHE 78 78 78 PHE PHE A . n A 1 79 GLY 79 79 79 GLY GLY A . n A 1 80 SER 80 80 80 SER SER A . n A 1 81 ASN 81 81 81 ASN ASN A . n A 1 82 VAL 82 82 82 VAL VAL A . n A 1 83 ASP 83 83 83 ASP ASP A . n A 1 84 ASN 84 84 84 ASN ASN A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 LEU 86 86 86 LEU LEU A . n A 1 87 LEU 87 87 87 LEU LEU A . n A 1 88 THR 88 88 88 THR THR A . n A 1 89 ALA 89 89 89 ALA ALA A . n A 1 90 GLU 90 90 90 GLU GLU A . n A 1 91 TYR 91 91 91 TYR TYR A . n A 1 92 GLN 92 92 92 GLN GLN A . n A 1 93 THR 93 93 93 THR THR A . n A 1 94 SER 94 94 94 SER SER A . n A 1 95 ASN 95 95 95 ASN ASN A . n A 1 96 ARG 96 96 96 ARG ARG A . n A 1 97 PHE 97 97 97 PHE PHE A . n A 1 98 HIS 98 98 98 HIS HIS A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 LYS 100 100 100 LYS LYS A . n A 1 101 LEU 101 101 101 LEU LEU A . n A 1 102 THR 102 102 102 THR THR A . n A 1 103 ASP 103 103 103 ASP ASP A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 THR 105 105 105 THR THR A . n A 1 106 ASN 106 106 106 ASN ASN A . n A 1 107 ASN 107 107 107 ASN ASN A . n A 1 108 ARG 108 108 108 ARG ARG A . n A 1 109 PHE 109 109 109 PHE PHE A . n A 1 110 GLU 110 110 110 GLU GLU A . n A 1 111 VAL 111 111 111 VAL VAL A . n A 1 112 PRO 112 112 112 PRO PRO A . n A 1 113 HIS 113 113 113 HIS HIS A . n A 1 114 GLU 114 114 114 GLU GLU A . n A 1 115 HIS 115 115 115 HIS HIS A . n A 1 116 VAL 116 116 116 VAL VAL A . n A 1 117 GLN 117 117 117 GLN GLN A . n A 1 118 SER 118 118 118 SER SER A . n A 1 119 PHE 119 119 119 PHE PHE A . n A 1 120 SER 120 120 120 SER SER A . n A 1 121 GLY 121 121 121 GLY GLY A . n A 1 122 ASN 122 122 122 ASN ASN A . n A 1 123 ALA 123 123 123 ALA ALA A . n A 1 124 ALA 124 124 124 ALA ALA A . n A 1 125 ALA 125 125 125 ALA ALA A . n A 1 126 SER 126 126 126 SER SER A . n A 1 127 LEU 127 127 127 LEU LEU A . n A 1 128 THR 128 128 128 THR THR A . n A 1 129 TYR 129 129 129 TYR TYR A . n A 1 130 GLN 130 130 130 GLN GLN A . n A 1 131 VAL 131 131 131 VAL VAL A . n A 1 132 GLU 132 132 132 GLU GLU A . n A 1 133 ILE 133 133 133 ILE ILE A . n A 1 134 SER 134 134 134 SER SER A . n A 1 135 ARG 135 135 135 ARG ARG A . n A 1 136 GLN 136 136 136 GLN GLN A . n A 1 137 PRO 137 137 137 PRO PRO A . n A 1 138 PHE 138 138 138 PHE PHE A . n A 1 139 SER 139 139 139 SER SER A . n A 1 140 ILE 140 140 140 ILE ILE A . n A 1 141 LYS 141 141 141 LYS LYS A . n A 1 142 VAL 142 142 142 VAL VAL A . n A 1 143 THR 143 143 143 THR THR A . n A 1 144 ARG 144 144 144 ARG ARG A . n A 1 145 ARG 145 145 145 ARG ARG A . n A 1 146 SER 146 146 146 SER SER A . n A 1 147 ASN 147 147 147 ASN ASN A . n A 1 148 ASN 148 148 148 ASN ASN A . n A 1 149 ARG 149 149 149 ARG ARG A . n A 1 150 VAL 150 150 150 VAL VAL A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 PHE 152 152 152 PHE PHE A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 SER 154 154 154 SER SER A . n A 1 155 SER 155 155 155 SER SER A . n A 1 156 ILE 156 156 156 ILE ILE A . n A 1 157 GLY 157 157 157 GLY GLY A . n A 1 158 PRO 158 158 158 PRO PRO A . n A 1 159 LEU 159 159 159 LEU LEU A . n A 1 160 LEU 160 160 160 LEU LEU A . n A 1 161 PHE 161 161 161 PHE PHE A . n A 1 162 ALA 162 162 162 ALA ALA A . n A 1 163 ASP 163 163 163 ASP ASP A . n A 1 164 GLN 164 164 164 GLN GLN A . n A 1 165 PHE 165 165 165 PHE PHE A . n A 1 166 LEU 166 166 166 LEU LEU A . n A 1 167 GLN 167 167 167 GLN GLN A . n A 1 168 LEU 168 168 168 LEU LEU A . n A 1 169 SER 169 169 169 SER SER A . n A 1 170 THR 170 170 170 THR THR A . n A 1 171 ARG 171 171 171 ARG ARG A . n A 1 172 LEU 172 172 172 LEU LEU A . n A 1 173 PRO 173 173 173 PRO PRO A . n A 1 174 SER 174 174 174 SER SER A . n A 1 175 THR 175 175 175 THR THR A . n A 1 176 ASN 176 176 176 ASN ASN A . n A 1 177 VAL 177 177 177 VAL VAL A . n A 1 178 TYR 178 178 178 TYR TYR A . n A 1 179 GLY 179 179 179 GLY GLY A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLY 181 181 181 GLY GLY A . n A 1 182 GLU 182 182 182 GLU GLU A . n A 1 183 HIS 183 183 183 HIS HIS A . n A 1 184 VAL 184 184 184 VAL VAL A . n A 1 185 HIS 185 185 185 HIS HIS A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 GLN 187 187 187 GLN GLN A . n A 1 188 TYR 188 188 188 TYR TYR A . n A 1 189 ARG 189 189 189 ARG ARG A . n A 1 190 HIS 190 190 190 HIS HIS A . n A 1 191 ASP 191 191 191 ASP ASP A . n A 1 192 MET 192 192 192 MET MET A . n A 1 193 ASN 193 193 193 ASN ASN A . n A 1 194 TRP 194 194 194 TRP TRP A . n A 1 195 LYS 195 195 195 LYS LYS A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 TRP 197 197 197 TRP TRP A . n A 1 198 PRO 198 198 198 PRO PRO A . n A 1 199 ILE 199 199 199 ILE ILE A . n A 1 200 PHE 200 200 200 PHE PHE A . n A 1 201 ASN 201 201 201 ASN ASN A . n A 1 202 ARG 202 202 202 ARG ARG A . n A 1 203 ASP 203 203 203 ASP ASP A . n A 1 204 THR 204 204 204 THR THR A . n A 1 205 THR 205 205 205 THR THR A . n A 1 206 PRO 206 206 206 PRO PRO A . n A 1 207 ASN 207 207 207 ASN ASN A . n A 1 208 GLY 208 208 208 GLY GLY A . n A 1 209 ASN 209 209 209 ASN ASN A . n A 1 210 GLY 210 210 210 GLY GLY A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 ASN 212 212 212 ASN ASN A . n A 1 213 LEU 213 213 213 LEU LEU A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 GLY 215 215 215 GLY GLY A . n A 1 216 ALA 216 216 216 ALA ALA A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 THR 218 218 218 THR THR A . n A 1 219 PHE 219 219 219 PHE PHE A . n A 1 220 PHE 220 220 220 PHE PHE A . n A 1 221 LEU 221 221 221 LEU LEU A . n A 1 222 CYS 222 222 222 CYS CYS A . n A 1 223 LEU 223 223 223 LEU LEU A . n A 1 224 GLU 224 224 224 GLU GLU A . n A 1 225 ASP 225 225 225 ASP ASP A . n A 1 226 ALA 226 226 226 ALA ALA A . n A 1 227 SER 227 227 227 SER SER A . n A 1 228 GLY 228 228 228 GLY GLY A . n A 1 229 LEU 229 229 229 LEU LEU A . n A 1 230 SER 230 230 230 SER SER A . n A 1 231 PHE 231 231 231 PHE PHE A . n A 1 232 GLY 232 232 232 GLY GLY A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 PHE 234 234 234 PHE PHE A . n A 1 235 LEU 235 235 235 LEU LEU A . n A 1 236 MET 236 236 236 MET MET A . n A 1 237 ASN 237 237 237 ASN ASN A . n A 1 238 SER 238 238 238 SER SER A . n A 1 239 ASN 239 239 239 ASN ASN A . n A 1 240 ALA 240 240 240 ALA ALA A . n A 1 241 MET 241 241 241 MET MET A . n A 1 242 GLU 242 242 242 GLU GLU A . n A 1 243 VAL 243 243 243 VAL VAL A . n A 1 244 VAL 244 244 244 VAL VAL A . n A 1 245 LEU 245 245 245 LEU LEU A . n A 1 246 GLN 246 246 246 GLN GLN A . n A 1 247 PRO 247 247 247 PRO PRO A . n A 1 248 ALA 248 248 248 ALA ALA A . n A 1 249 PRO 249 249 249 PRO PRO A . n A 1 250 ALA 250 250 250 ALA ALA A . n A 1 251 ILE 251 251 251 ILE ILE A . n A 1 252 THR 252 252 252 THR THR A . n A 1 253 TYR 253 253 253 TYR TYR A . n A 1 254 ARG 254 254 254 ARG ARG A . n A 1 255 THR 255 255 255 THR THR A . n A 1 256 ILE 256 256 256 ILE ILE A . n A 1 257 GLY 257 257 257 GLY GLY A . n A 1 258 GLY 258 258 258 GLY GLY A . n A 1 259 ILE 259 259 259 ILE ILE A . n A 1 260 LEU 260 260 260 LEU LEU A . n A 1 261 ASP 261 261 261 ASP ASP A . n A 1 262 PHE 262 262 262 PHE PHE A . n A 1 263 TYR 263 263 263 TYR TYR A . n A 1 264 VAL 264 264 264 VAL VAL A . n A 1 265 PHE 265 265 265 PHE PHE A . n A 1 266 LEU 266 266 266 LEU LEU A . n A 1 267 GLY 267 267 267 GLY GLY A . n A 1 268 ASN 268 268 268 ASN ASN A . n A 1 269 THR 269 269 269 THR THR A . n A 1 270 PRO 270 270 270 PRO PRO A . n A 1 271 GLU 271 271 271 GLU GLU A . n A 1 272 GLN 272 272 272 GLN GLN A . n A 1 273 VAL 273 273 273 VAL VAL A . n A 1 274 VAL 274 274 274 VAL VAL A . n A 1 275 GLN 275 275 275 GLN GLN A . n A 1 276 GLU 276 276 276 GLU GLU A . n A 1 277 TYR 277 277 277 TYR TYR A . n A 1 278 LEU 278 278 278 LEU LEU A . n A 1 279 GLU 279 279 279 GLU GLU A . n A 1 280 LEU 280 280 280 LEU LEU A . n A 1 281 ILE 281 281 281 ILE ILE A . n A 1 282 GLY 282 282 282 GLY GLY A . n A 1 283 ARG 283 283 283 ARG ARG A . n A 1 284 PRO 284 284 284 PRO PRO A . n A 1 285 ALA 285 285 285 ALA ALA A . n A 1 286 LEU 286 286 286 LEU LEU A . n A 1 287 PRO 287 287 287 PRO PRO A . n A 1 288 SER 288 288 288 SER SER A . n A 1 289 TYR 289 289 289 TYR TYR A . n A 1 290 TRP 290 290 290 TRP TRP A . n A 1 291 ALA 291 291 291 ALA ALA A . n A 1 292 LEU 292 292 292 LEU LEU A . n A 1 293 GLY 293 293 293 GLY GLY A . n A 1 294 PHE 294 294 294 PHE PHE A . n A 1 295 HIS 295 295 295 HIS HIS A . n A 1 296 LEU 296 296 296 LEU LEU A . n A 1 297 SER 297 297 297 SER SER A . n A 1 298 ARG 298 298 298 ARG ARG A . n A 1 299 TYR 299 299 299 TYR TYR A . n A 1 300 GLU 300 300 300 GLU GLU A . n A 1 301 TYR 301 301 301 TYR TYR A . n A 1 302 GLY 302 302 302 GLY GLY A . n A 1 303 THR 303 303 303 THR THR A . n A 1 304 LEU 304 304 304 LEU LEU A . n A 1 305 ASP 305 305 305 ASP ASP A . n A 1 306 ASN 306 306 306 ASN ASN A . n A 1 307 MET 307 307 307 MET MET A . n A 1 308 ARG 308 308 308 ARG ARG A . n A 1 309 GLU 309 309 309 GLU GLU A . n A 1 310 VAL 310 310 310 VAL VAL A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 GLU 312 312 312 GLU GLU A . n A 1 313 ARG 313 313 313 ARG ARG A . n A 1 314 ASN 314 314 314 ASN ASN A . n A 1 315 ARG 315 315 315 ARG ARG A . n A 1 316 ALA 316 316 316 ALA ALA A . n A 1 317 ALA 317 317 317 ALA ALA A . n A 1 318 GLN 318 318 318 GLN GLN A . n A 1 319 LEU 319 319 319 LEU LEU A . n A 1 320 PRO 320 320 320 PRO PRO A . n A 1 321 TYR 321 321 321 TYR TYR A . n A 1 322 ASP 322 322 322 ASP ASP A . n A 1 323 VAL 323 323 323 VAL VAL A . n A 1 324 GLN 324 324 324 GLN GLN A . n A 1 325 HIS 325 325 325 HIS HIS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 ASP 327 327 327 ASP ASP A . n A 1 328 ILE 328 328 328 ILE ILE A . n A 1 329 ASP 329 329 329 ASP ASP A . n A 1 330 TYR 330 330 330 TYR TYR A . n A 1 331 MET 331 331 331 MET MET A . n A 1 332 ASP 332 332 332 ASP ASP A . n A 1 333 GLU 333 333 333 GLU GLU A . n A 1 334 ARG 334 334 334 ARG ARG A . n A 1 335 ARG 335 335 335 ARG ARG A . n A 1 336 ASP 336 336 336 ASP ASP A . n A 1 337 PHE 337 337 337 PHE PHE A . n A 1 338 THR 338 338 338 THR THR A . n A 1 339 TYR 339 339 339 TYR TYR A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 SER 341 341 341 SER SER A . n A 1 342 VAL 342 342 342 VAL VAL A . n A 1 343 ASP 343 343 343 ASP ASP A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLY 346 346 346 GLY GLY A . n A 1 347 PHE 347 347 347 PHE PHE A . n A 1 348 PRO 348 348 348 PRO PRO A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 PHE 350 350 350 PHE PHE A . n A 1 351 VAL 351 351 351 VAL VAL A . n A 1 352 ASN 352 352 352 ASN ASN A . n A 1 353 GLU 353 353 353 GLU GLU A . n A 1 354 LEU 354 354 354 LEU LEU A . n A 1 355 HIS 355 355 355 HIS HIS A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 ASN 357 357 357 ASN ASN A . n A 1 358 GLY 358 358 358 GLY GLY A . n A 1 359 GLN 359 359 359 GLN GLN A . n A 1 360 LYS 360 360 360 LYS LYS A . n A 1 361 LEU 361 361 361 LEU LEU A . n A 1 362 VAL 362 362 362 VAL VAL A . n A 1 363 ILE 363 363 363 ILE ILE A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 VAL 365 365 365 VAL VAL A . n A 1 366 ASP 366 366 366 ASP ASP A . n A 1 367 PRO 367 367 367 PRO PRO A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 ILE 369 369 369 ILE ILE A . n A 1 370 SER 370 370 370 SER SER A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 ASN 372 372 372 ASN ASN A . n A 1 373 SER 373 373 373 SER SER A . n A 1 374 SER 374 374 374 SER SER A . n A 1 375 SER 375 375 375 SER SER A . n A 1 376 SER 376 376 376 SER SER A . n A 1 377 LYS 377 377 377 LYS LYS A . n A 1 378 PRO 378 378 378 PRO PRO A . n A 1 379 TYR 379 379 379 TYR TYR A . n A 1 380 GLY 380 380 380 GLY GLY A . n A 1 381 PRO 381 381 381 PRO PRO A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 ASP 383 383 383 ASP ASP A . n A 1 384 ARG 384 384 384 ARG ARG A . n A 1 385 GLY 385 385 385 GLY GLY A . n A 1 386 SER 386 386 386 SER SER A . n A 1 387 ASP 387 387 387 ASP ASP A . n A 1 388 MET 388 388 388 MET MET A . n A 1 389 LYS 389 389 389 LYS LYS A . n A 1 390 ILE 390 390 390 ILE ILE A . n A 1 391 TRP 391 391 391 TRP TRP A . n A 1 392 VAL 392 392 392 VAL VAL A . n A 1 393 ASN 393 393 393 ASN ASN A . n A 1 394 SER 394 394 394 SER SER A . n A 1 395 SER 395 395 395 SER SER A . n A 1 396 ASP 396 396 396 ASP ASP A . n A 1 397 GLY 397 397 397 GLY GLY A . n A 1 398 VAL 398 398 398 VAL VAL A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 PRO 400 400 400 PRO PRO A . n A 1 401 LEU 401 401 401 LEU LEU A . n A 1 402 ILE 402 402 402 ILE ILE A . n A 1 403 GLY 403 403 403 GLY GLY A . n A 1 404 GLU 404 404 404 GLU GLU A . n A 1 405 VAL 405 405 405 VAL VAL A . n A 1 406 TRP 406 406 406 TRP TRP A . n A 1 407 PRO 407 407 407 PRO PRO A . n A 1 408 GLY 408 408 408 GLY GLY A . n A 1 409 GLN 409 409 409 GLN GLN A . n A 1 410 THR 410 410 410 THR THR A . n A 1 411 VAL 411 411 411 VAL VAL A . n A 1 412 PHE 412 412 412 PHE PHE A . n A 1 413 PRO 413 413 413 PRO PRO A . n A 1 414 ASP 414 414 414 ASP ASP A . n A 1 415 TYR 415 415 415 TYR TYR A . n A 1 416 THR 416 416 416 THR THR A . n A 1 417 ASN 417 417 417 ASN ASN A . n A 1 418 PRO 418 418 418 PRO PRO A . n A 1 419 ASN 419 419 419 ASN ASN A . n A 1 420 CYS 420 420 420 CYS CYS A . n A 1 421 ALA 421 421 421 ALA ALA A . n A 1 422 VAL 422 422 422 VAL VAL A . n A 1 423 TRP 423 423 423 TRP TRP A . n A 1 424 TRP 424 424 424 TRP TRP A . n A 1 425 THR 425 425 425 THR THR A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 GLU 427 427 427 GLU GLU A . n A 1 428 PHE 428 428 428 PHE PHE A . n A 1 429 GLU 429 429 429 GLU GLU A . n A 1 430 LEU 430 430 430 LEU LEU A . n A 1 431 PHE 431 431 431 PHE PHE A . n A 1 432 HIS 432 432 432 HIS HIS A . n A 1 433 ASN 433 433 433 ASN ASN A . n A 1 434 GLN 434 434 434 GLN GLN A . n A 1 435 VAL 435 435 435 VAL VAL A . n A 1 436 GLU 436 436 436 GLU GLU A . n A 1 437 PHE 437 437 437 PHE PHE A . n A 1 438 ASP 438 438 438 ASP ASP A . n A 1 439 GLY 439 439 439 GLY GLY A . n A 1 440 ILE 440 440 440 ILE ILE A . n A 1 441 TRP 441 441 441 TRP TRP A . n A 1 442 ILE 442 442 442 ILE ILE A . n A 1 443 ASP 443 443 443 ASP ASP A . n A 1 444 MET 444 444 444 MET MET A . n A 1 445 ASN 445 445 445 ASN ASN A . n A 1 446 GLU 446 446 446 GLU GLU A . n A 1 447 VAL 447 447 447 VAL VAL A . n A 1 448 SER 448 448 448 SER SER A . n A 1 449 ASN 449 449 449 ASN ASN A . n A 1 450 PHE 450 450 450 PHE PHE A . n A 1 451 VAL 451 451 451 VAL VAL A . n A 1 452 ASP 452 452 452 ASP ASP A . n A 1 453 GLY 453 453 453 GLY GLY A . n A 1 454 SER 454 454 454 SER SER A . n A 1 455 VAL 455 455 455 VAL VAL A . n A 1 456 SER 456 456 456 SER SER A . n A 1 457 GLY 457 457 457 GLY GLY A . n A 1 458 CYS 458 458 458 CYS CYS A . n A 1 459 SER 459 459 459 SER SER A . n A 1 460 THR 460 460 460 THR THR A . n A 1 461 ASN 461 461 461 ASN ASN A . n A 1 462 ASN 462 462 462 ASN ASN A . n A 1 463 LEU 463 463 463 LEU LEU A . n A 1 464 ASN 464 464 464 ASN ASN A . n A 1 465 ASN 465 465 465 ASN ASN A . n A 1 466 PRO 466 466 466 PRO PRO A . n A 1 467 PRO 467 467 467 PRO PRO A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 THR 469 469 469 THR THR A . n A 1 470 PRO 470 470 470 PRO PRO A . n A 1 471 ARG 471 471 471 ARG ARG A . n A 1 472 ILE 472 472 472 ILE ILE A . n A 1 473 LEU 473 473 473 LEU LEU A . n A 1 474 ASP 474 474 474 ASP ASP A . n A 1 475 GLY 475 475 475 GLY GLY A . n A 1 476 TYR 476 476 476 TYR TYR A . n A 1 477 LEU 477 477 477 LEU LEU A . n A 1 478 PHE 478 478 478 PHE PHE A . n A 1 479 CYS 479 479 479 CYS CYS A . n A 1 480 LYS 480 480 480 LYS LYS A . n A 1 481 THR 481 481 481 THR THR A . n A 1 482 LEU 482 482 482 LEU LEU A . n A 1 483 CYS 483 483 483 CYS CYS A . n A 1 484 MET 484 484 484 MET MET A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 ALA 486 486 486 ALA ALA A . n A 1 487 VAL 487 487 487 VAL VAL A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 HIS 489 489 489 HIS HIS A . n A 1 490 TRP 490 490 490 TRP TRP A . n A 1 491 GLY 491 491 491 GLY GLY A . n A 1 492 LYS 492 492 492 LYS LYS A . n A 1 493 GLN 493 493 493 GLN GLN A . n A 1 494 TYR 494 494 494 TYR TYR A . n A 1 495 ASP 495 495 495 ASP ASP A . n A 1 496 ILE 496 496 496 ILE ILE A . n A 1 497 HIS 497 497 497 HIS HIS A . n A 1 498 ASN 498 498 498 ASN ASN A . n A 1 499 LEU 499 499 499 LEU LEU A . n A 1 500 TYR 500 500 500 TYR TYR A . n A 1 501 GLY 501 501 501 GLY GLY A . n A 1 502 TYR 502 502 502 TYR TYR A . n A 1 503 SER 503 503 503 SER SER A . n A 1 504 MET 504 504 504 MET MET A . n A 1 505 ALA 505 505 505 ALA ALA A . n A 1 506 VAL 506 506 506 VAL VAL A . n A 1 507 ALA 507 507 507 ALA ALA A . n A 1 508 THR 508 508 508 THR THR A . n A 1 509 ALA 509 509 509 ALA ALA A . n A 1 510 GLU 510 510 510 GLU GLU A . n A 1 511 ALA 511 511 511 ALA ALA A . n A 1 512 ALA 512 512 512 ALA ALA A . n A 1 513 LYS 513 513 513 LYS LYS A . n A 1 514 THR 514 514 514 THR THR A . n A 1 515 VAL 515 515 515 VAL VAL A . n A 1 516 PHE 516 516 516 PHE PHE A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASN 518 518 518 ASN ASN A . n A 1 519 LYS 519 519 519 LYS LYS A . n A 1 520 ARG 520 520 520 ARG ARG A . n A 1 521 SER 521 521 521 SER SER A . n A 1 522 PHE 522 522 522 PHE PHE A . n A 1 523 ILE 523 523 523 ILE ILE A . n A 1 524 LEU 524 524 524 LEU LEU A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 ARG 526 526 526 ARG ARG A . n A 1 527 SER 527 527 527 SER SER A . n A 1 528 THR 528 528 528 THR THR A . n A 1 529 PHE 529 529 529 PHE PHE A . n A 1 530 ALA 530 530 530 ALA ALA A . n A 1 531 GLY 531 531 531 GLY GLY A . n A 1 532 SER 532 532 532 SER SER A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 LYS 534 534 534 LYS LYS A . n A 1 535 PHE 535 535 535 PHE PHE A . n A 1 536 ALA 536 536 536 ALA ALA A . n A 1 537 ALA 537 537 537 ALA ALA A . n A 1 538 HIS 538 538 538 HIS HIS A . n A 1 539 TRP 539 539 539 TRP TRP A . n A 1 540 LEU 540 540 540 LEU LEU A . n A 1 541 GLY 541 541 541 GLY GLY A . n A 1 542 ASP 542 542 542 ASP ASP A . n A 1 543 ASN 543 543 543 ASN ASN A . n A 1 544 THR 544 544 544 THR THR A . n A 1 545 ALA 545 545 545 ALA ALA A . n A 1 546 THR 546 546 546 THR THR A . n A 1 547 TRP 547 547 547 TRP TRP A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ASP 549 549 549 ASP ASP A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 ARG 551 551 551 ARG ARG A . n A 1 552 TRP 552 552 552 TRP TRP A . n A 1 553 SER 553 553 553 SER SER A . n A 1 554 ILE 554 554 554 ILE ILE A . n A 1 555 PRO 555 555 555 PRO PRO A . n A 1 556 GLY 556 556 556 GLY GLY A . n A 1 557 VAL 557 557 557 VAL VAL A . n A 1 558 LEU 558 558 558 LEU LEU A . n A 1 559 GLU 559 559 559 GLU GLU A . n A 1 560 PHE 560 560 560 PHE PHE A . n A 1 561 ASN 561 561 561 ASN ASN A . n A 1 562 LEU 562 562 562 LEU LEU A . n A 1 563 PHE 563 563 563 PHE PHE A . n A 1 564 GLY 564 564 564 GLY GLY A . n A 1 565 ILE 565 565 565 ILE ILE A . n A 1 566 PRO 566 566 566 PRO PRO A . n A 1 567 MET 567 567 567 MET MET A . n A 1 568 VAL 568 568 568 VAL VAL A . n A 1 569 GLY 569 569 569 GLY GLY A . n A 1 570 PRO 570 570 570 PRO PRO A . n A 1 571 ASP 571 571 571 ASP ASP A . n A 1 572 ILE 572 572 572 ILE ILE A . n A 1 573 CYS 573 573 573 CYS CYS A . n A 1 574 GLY 574 574 574 GLY GLY A . n A 1 575 PHE 575 575 575 PHE PHE A . n A 1 576 ALA 576 576 576 ALA ALA A . n A 1 577 LEU 577 577 577 LEU LEU A . n A 1 578 ASP 578 578 578 ASP ASP A . n A 1 579 THR 579 579 579 THR THR A . n A 1 580 PRO 580 580 580 PRO PRO A . n A 1 581 GLU 581 581 581 GLU GLU A . n A 1 582 GLU 582 582 582 GLU GLU A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 CYS 584 584 584 CYS CYS A . n A 1 585 ARG 585 585 585 ARG ARG A . n A 1 586 ARG 586 586 586 ARG ARG A . n A 1 587 TRP 587 587 587 TRP TRP A . n A 1 588 MET 588 588 588 MET MET A . n A 1 589 GLN 589 589 589 GLN GLN A . n A 1 590 LEU 590 590 590 LEU LEU A . n A 1 591 GLY 591 591 591 GLY GLY A . n A 1 592 ALA 592 592 592 ALA ALA A . n A 1 593 PHE 593 593 593 PHE PHE A . n A 1 594 TYR 594 594 594 TYR TYR A . n A 1 595 PRO 595 595 595 PRO PRO A . n A 1 596 PHE 596 596 596 PHE PHE A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 ARG 598 598 598 ARG ARG A . n A 1 599 ASN 599 599 599 ASN ASN A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASN 601 601 601 ASN ASN A . n A 1 602 GLY 602 602 602 GLY GLY A . n A 1 603 GLN 603 603 603 GLN GLN A . n A 1 604 GLY 604 604 604 GLY GLY A . n A 1 605 TYR 605 605 605 TYR TYR A . n A 1 606 LYS 606 606 606 LYS LYS A . n A 1 607 ASP 607 607 607 ASP ASP A . n A 1 608 GLN 608 608 608 GLN GLN A . n A 1 609 ASP 609 609 609 ASP ASP A . n A 1 610 PRO 610 610 610 PRO PRO A . n A 1 611 ALA 611 611 611 ALA ALA A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 PHE 613 613 613 PHE PHE A . n A 1 614 GLY 614 614 614 GLY GLY A . n A 1 615 ALA 615 615 615 ALA ALA A . n A 1 616 ASP 616 616 616 ASP ASP A . n A 1 617 SER 617 617 617 SER SER A . n A 1 618 LEU 618 618 618 LEU LEU A . n A 1 619 LEU 619 619 619 LEU LEU A . n A 1 620 LEU 620 620 620 LEU LEU A . n A 1 621 ASN 621 621 621 ASN ASN A . n A 1 622 SER 622 622 622 SER SER A . n A 1 623 SER 623 623 623 SER SER A . n A 1 624 ARG 624 624 624 ARG ARG A . n A 1 625 HIS 625 625 625 HIS HIS A . n A 1 626 TYR 626 626 626 TYR TYR A . n A 1 627 LEU 627 627 627 LEU LEU A . n A 1 628 ASN 628 628 628 ASN ASN A . n A 1 629 ILE 629 629 629 ILE ILE A . n A 1 630 ARG 630 630 630 ARG ARG A . n A 1 631 TYR 631 631 631 TYR TYR A . n A 1 632 THR 632 632 632 THR THR A . n A 1 633 LEU 633 633 633 LEU LEU A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 PRO 635 635 635 PRO PRO A . n A 1 636 TYR 636 636 636 TYR TYR A . n A 1 637 LEU 637 637 637 LEU LEU A . n A 1 638 TYR 638 638 638 TYR TYR A . n A 1 639 THR 639 639 639 THR THR A . n A 1 640 LEU 640 640 640 LEU LEU A . n A 1 641 PHE 641 641 641 PHE PHE A . n A 1 642 PHE 642 642 642 PHE PHE A . n A 1 643 ARG 643 643 643 ARG ARG A . n A 1 644 ALA 644 644 644 ALA ALA A . n A 1 645 HIS 645 645 645 HIS HIS A . n A 1 646 SER 646 646 646 SER SER A . n A 1 647 ARG 647 647 647 ARG ARG A . n A 1 648 GLY 648 648 648 GLY GLY A . n A 1 649 ASP 649 649 649 ASP ASP A . n A 1 650 THR 650 650 650 THR THR A . n A 1 651 VAL 651 651 651 VAL VAL A . n A 1 652 ALA 652 652 652 ALA ALA A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 PRO 654 654 654 PRO PRO A . n A 1 655 LEU 655 655 655 LEU LEU A . n A 1 656 LEU 656 656 656 LEU LEU A . n A 1 657 HIS 657 657 657 HIS HIS A . n A 1 658 GLU 658 658 658 GLU GLU A . n A 1 659 PHE 659 659 659 PHE PHE A . n A 1 660 TYR 660 660 660 TYR TYR A . n A 1 661 GLU 661 661 661 GLU GLU A . n A 1 662 ASP 662 662 662 ASP ASP A . n A 1 663 ASN 663 663 663 ASN ASN A . n A 1 664 SER 664 664 664 SER SER A . n A 1 665 THR 665 665 665 THR THR A . n A 1 666 TRP 666 666 666 TRP TRP A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 HIS 669 669 669 HIS HIS A . n A 1 670 GLN 670 670 670 GLN GLN A . n A 1 671 GLN 671 671 671 GLN GLN A . n A 1 672 PHE 672 672 672 PHE PHE A . n A 1 673 LEU 673 673 673 LEU LEU A . n A 1 674 TRP 674 674 674 TRP TRP A . n A 1 675 GLY 675 675 675 GLY GLY A . n A 1 676 PRO 676 676 676 PRO PRO A . n A 1 677 GLY 677 677 677 GLY GLY A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 LEU 679 679 679 LEU LEU A . n A 1 680 ILE 680 680 680 ILE ILE A . n A 1 681 THR 681 681 681 THR THR A . n A 1 682 PRO 682 682 682 PRO PRO A . n A 1 683 VAL 683 683 683 VAL VAL A . n A 1 684 LEU 684 684 684 LEU LEU A . n A 1 685 ASP 685 685 685 ASP ASP A . n A 1 686 GLU 686 686 686 GLU GLU A . n A 1 687 GLY 687 687 687 GLY GLY A . n A 1 688 ALA 688 688 688 ALA ALA A . n A 1 689 GLU 689 689 689 GLU GLU A . n A 1 690 LYS 690 690 690 LYS LYS A . n A 1 691 VAL 691 691 691 VAL VAL A . n A 1 692 MET 692 692 692 MET MET A . n A 1 693 ALA 693 693 693 ALA ALA A . n A 1 694 TYR 694 694 694 TYR TYR A . n A 1 695 VAL 695 695 695 VAL VAL A . n A 1 696 PRO 696 696 696 PRO PRO A . n A 1 697 ASP 697 697 697 ASP ASP A . n A 1 698 ALA 698 698 698 ALA ALA A . n A 1 699 VAL 699 699 699 VAL VAL A . n A 1 700 TRP 700 700 700 TRP TRP A . n A 1 701 TYR 701 701 701 TYR TYR A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 TYR 703 703 703 TYR TYR A . n A 1 704 GLU 704 704 704 GLU GLU A . n A 1 705 THR 705 705 705 THR THR A . n A 1 706 GLY 706 706 706 GLY GLY A . n A 1 707 SER 707 707 707 SER SER A . n A 1 708 GLN 708 708 708 GLN GLN A . n A 1 709 VAL 709 709 709 VAL VAL A . n A 1 710 ARG 710 710 710 ARG ARG A . n A 1 711 TRP 711 711 711 TRP TRP A . n A 1 712 ARG 712 712 712 ARG ARG A . n A 1 713 LYS 713 713 713 LYS LYS A . n A 1 714 GLN 714 714 714 GLN GLN A . n A 1 715 LYS 715 715 715 LYS LYS A . n A 1 716 VAL 716 716 716 VAL VAL A . n A 1 717 GLU 717 717 717 GLU GLU A . n A 1 718 MET 718 718 718 MET MET A . n A 1 719 GLU 719 719 719 GLU GLU A . n A 1 720 LEU 720 720 720 LEU LEU A . n A 1 721 PRO 721 721 721 PRO PRO A . n A 1 722 GLY 722 722 722 GLY GLY A . n A 1 723 ASP 723 723 723 ASP ASP A . n A 1 724 LYS 724 724 724 LYS LYS A . n A 1 725 ILE 725 725 725 ILE ILE A . n A 1 726 GLY 726 726 726 GLY GLY A . n A 1 727 LEU 727 727 727 LEU LEU A . n A 1 728 HIS 728 728 728 HIS HIS A . n A 1 729 LEU 729 729 729 LEU LEU A . n A 1 730 ARG 730 730 730 ARG ARG A . n A 1 731 GLY 731 731 731 GLY GLY A . n A 1 732 GLY 732 732 732 GLY GLY A . n A 1 733 TYR 733 733 733 TYR TYR A . n A 1 734 ILE 734 734 734 ILE ILE A . n A 1 735 PHE 735 735 735 PHE PHE A . n A 1 736 PRO 736 736 736 PRO PRO A . n A 1 737 THR 737 737 737 THR THR A . n A 1 738 GLN 738 738 738 GLN GLN A . n A 1 739 GLN 739 739 739 GLN GLN A . n A 1 740 PRO 740 740 740 PRO PRO A . n A 1 741 ASN 741 741 741 ASN ASN A . n A 1 742 THR 742 742 742 THR THR A . n A 1 743 THR 743 743 743 THR THR A . n A 1 744 THR 744 744 744 THR THR A . n A 1 745 LEU 745 745 745 LEU LEU A . n A 1 746 ALA 746 746 746 ALA ALA A . n A 1 747 SER 747 747 747 SER SER A . n A 1 748 ARG 748 748 748 ARG ARG A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 ASN 750 750 750 ASN ASN A . n A 1 751 PRO 751 751 751 PRO PRO A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLY 753 753 753 GLY GLY A . n A 1 754 LEU 754 754 754 LEU LEU A . n A 1 755 ILE 755 755 755 ILE ILE A . n A 1 756 ILE 756 756 756 ILE ILE A . n A 1 757 ALA 757 757 757 ALA ALA A . n A 1 758 LEU 758 758 758 LEU LEU A . n A 1 759 ASP 759 759 759 ASP ASP A . n A 1 760 GLU 760 760 760 GLU GLU A . n A 1 761 ASN 761 761 761 ASN ASN A . n A 1 762 LYS 762 762 762 LYS LYS A . n A 1 763 GLU 763 763 763 GLU GLU A . n A 1 764 ALA 764 764 764 ALA ALA A . n A 1 765 LYS 765 765 765 LYS LYS A . n A 1 766 GLY 766 766 766 GLY GLY A . n A 1 767 GLU 767 767 767 GLU GLU A . n A 1 768 LEU 768 768 768 LEU LEU A . n A 1 769 PHE 769 769 769 PHE PHE A . n A 1 770 TRP 770 770 770 TRP TRP A . n A 1 771 ASP 771 771 771 ASP ASP A . n A 1 772 ASP 772 772 772 ASP ASP A . n A 1 773 GLY 773 773 773 GLY GLY A . n A 1 774 GLU 774 774 774 GLU GLU A . n A 1 775 THR 775 775 775 THR THR A . n A 1 776 LYS 776 776 776 LYS LYS A . n A 1 777 ASP 777 777 777 ASP ASP A . n A 1 778 THR 778 778 778 THR THR A . n A 1 779 VAL 779 779 779 VAL VAL A . n A 1 780 ALA 780 780 780 ALA ALA A . n A 1 781 ASN 781 781 781 ASN ASN A . n A 1 782 LYS 782 782 782 LYS LYS A . n A 1 783 VAL 783 783 783 VAL VAL A . n A 1 784 TYR 784 784 784 TYR TYR A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 LEU 786 786 786 LEU LEU A . n A 1 787 CYS 787 787 787 CYS CYS A . n A 1 788 GLU 788 788 788 GLU GLU A . n A 1 789 PHE 789 789 789 PHE PHE A . n A 1 790 SER 790 790 790 SER SER A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 THR 792 792 792 THR THR A . n A 1 793 GLN 793 793 793 GLN GLN A . n A 1 794 ASN 794 794 794 ASN ASN A . n A 1 795 ARG 795 795 795 ARG ARG A . n A 1 796 LEU 796 796 796 LEU LEU A . n A 1 797 GLU 797 797 797 GLU GLU A . n A 1 798 VAL 798 798 798 VAL VAL A . n A 1 799 ASN 799 799 799 ASN ASN A . n A 1 800 ILE 800 800 800 ILE ILE A . n A 1 801 SER 801 801 801 SER SER A . n A 1 802 GLN 802 802 802 GLN GLN A . n A 1 803 SER 803 803 803 SER SER A . n A 1 804 THR 804 804 804 THR THR A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 LYS 806 806 806 LYS LYS A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 PRO 808 808 808 PRO PRO A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 ASN 810 810 810 ASN ASN A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 ALA 812 812 812 ALA ALA A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ASN 814 814 814 ASN ASN A . n A 1 815 GLU 815 815 815 GLU GLU A . n A 1 816 ILE 816 816 816 ILE ILE A . n A 1 817 LYS 817 817 817 LYS LYS A . n A 1 818 ILE 818 818 818 ILE ILE A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 GLY 820 820 820 GLY GLY A . n A 1 821 THR 821 821 821 THR THR A . n A 1 822 GLU 822 822 822 GLU GLU A . n A 1 823 GLU 823 823 823 GLU GLU A . n A 1 824 PRO 824 824 824 PRO PRO A . n A 1 825 SER 825 825 825 SER SER A . n A 1 826 ASN 826 826 826 ASN ASN A . n A 1 827 VAL 827 827 827 VAL VAL A . n A 1 828 THR 828 828 828 THR THR A . n A 1 829 VAL 829 829 829 VAL VAL A . n A 1 830 LYS 830 830 830 LYS LYS A . n A 1 831 HIS 831 831 831 HIS HIS A . n A 1 832 ASN 832 832 832 ASN ASN A . n A 1 833 GLY 833 833 833 GLY GLY A . n A 1 834 VAL 834 834 834 VAL VAL A . n A 1 835 PRO 835 835 835 PRO PRO A . n A 1 836 SER 836 836 836 SER SER A . n A 1 837 GLN 837 837 ? ? ? A . n A 1 838 THR 838 838 838 THR THR A . n A 1 839 SER 839 839 839 SER SER A . n A 1 840 PRO 840 840 840 PRO PRO A . n A 1 841 THR 841 841 841 THR THR A . n A 1 842 VAL 842 842 842 VAL VAL A . n A 1 843 THR 843 843 843 THR THR A . n A 1 844 TYR 844 844 844 TYR TYR A . n A 1 845 ASP 845 845 845 ASP ASP A . n A 1 846 SER 846 846 846 SER SER A . n A 1 847 ASN 847 847 847 ASN ASN A . n A 1 848 LEU 848 848 848 LEU LEU A . n A 1 849 LYS 849 849 849 LYS LYS A . n A 1 850 VAL 850 850 850 VAL VAL A . n A 1 851 ALA 851 851 851 ALA ALA A . n A 1 852 ILE 852 852 852 ILE ILE A . n A 1 853 ILE 853 853 853 ILE ILE A . n A 1 854 THR 854 854 854 THR THR A . n A 1 855 ASP 855 855 855 ASP ASP A . n A 1 856 ILE 856 856 856 ILE ILE A . n A 1 857 ASP 857 857 857 ASP ASP A . n A 1 858 LEU 858 858 858 LEU LEU A . n A 1 859 LEU 859 859 859 LEU LEU A . n A 1 860 LEU 860 860 860 LEU LEU A . n A 1 861 GLY 861 861 861 GLY GLY A . n A 1 862 GLU 862 862 862 GLU GLU A . n A 1 863 ALA 863 863 863 ALA ALA A . n A 1 864 TYR 864 864 864 TYR TYR A . n A 1 865 THR 865 865 865 THR THR A . n A 1 866 VAL 866 866 866 VAL VAL A . n A 1 867 GLU 867 867 867 GLU GLU A . n A 1 868 TRP 868 868 868 TRP TRP A . n A 1 869 ALA 869 869 869 ALA ALA A . n A 1 870 HIS 870 870 870 HIS HIS A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 ACR 1 1001 1001 ACR ACR A . C 3 NAG 1 2001 2001 NAG NAG A . D 3 NAG 1 2005 2005 NAG NAG A . E 4 SO4 1 4001 4001 SO4 SO4 A . F 5 GOL 1 3001 3001 GOL GOL A . G 5 GOL 1 3002 3002 GOL GOL A . H 5 GOL 1 3003 3003 GOL GOL A . I 5 GOL 1 3004 3004 GOL GOL A . J 5 GOL 1 3005 3005 GOL GOL A . K 5 GOL 1 3006 3006 GOL GOL A . L 5 GOL 1 3007 3007 GOL GOL A . M 5 GOL 1 3008 3008 GOL GOL A . N 5 GOL 1 3009 3009 GOL GOL A . O 3 NAG 1 2003 2003 NAG NAG X . P 3 NAG 2 2004 2004 NAG NAG X . Q 6 HOH 1 4002 1 HOH HOH A . Q 6 HOH 2 4003 2 HOH HOH A . Q 6 HOH 3 4004 3 HOH HOH A . Q 6 HOH 4 4005 4 HOH HOH A . Q 6 HOH 5 4006 5 HOH HOH A . Q 6 HOH 6 4007 6 HOH HOH A . Q 6 HOH 7 4008 7 HOH HOH A . Q 6 HOH 8 4009 8 HOH HOH A . Q 6 HOH 9 4010 9 HOH HOH A . Q 6 HOH 10 4011 10 HOH HOH A . Q 6 HOH 11 4012 11 HOH HOH A . Q 6 HOH 12 4013 12 HOH HOH A . Q 6 HOH 13 4014 13 HOH HOH A . Q 6 HOH 14 4015 14 HOH HOH A . Q 6 HOH 15 4016 15 HOH HOH A . Q 6 HOH 16 4017 16 HOH HOH A . Q 6 HOH 17 4018 17 HOH HOH A . Q 6 HOH 18 4019 18 HOH HOH A . Q 6 HOH 19 4020 19 HOH HOH A . Q 6 HOH 20 4021 20 HOH HOH A . Q 6 HOH 21 4022 21 HOH HOH A . Q 6 HOH 22 4023 22 HOH HOH A . Q 6 HOH 23 4024 23 HOH HOH A . Q 6 HOH 24 4025 24 HOH HOH A . Q 6 HOH 25 4026 25 HOH HOH A . Q 6 HOH 26 4027 26 HOH HOH A . Q 6 HOH 27 4028 27 HOH HOH A . Q 6 HOH 28 4029 28 HOH HOH A . Q 6 HOH 29 4030 29 HOH HOH A . Q 6 HOH 30 4031 30 HOH HOH A . Q 6 HOH 31 4032 31 HOH HOH A . Q 6 HOH 32 4033 32 HOH HOH A . Q 6 HOH 33 4034 33 HOH HOH A . Q 6 HOH 34 4035 34 HOH HOH A . Q 6 HOH 35 4036 35 HOH HOH A . Q 6 HOH 36 4037 36 HOH HOH A . Q 6 HOH 37 4038 37 HOH HOH A . Q 6 HOH 38 4039 38 HOH HOH A . Q 6 HOH 39 4040 39 HOH HOH A . Q 6 HOH 40 4041 40 HOH HOH A . Q 6 HOH 41 4042 41 HOH HOH A . Q 6 HOH 42 4043 43 HOH HOH A . Q 6 HOH 43 4044 44 HOH HOH A . Q 6 HOH 44 4045 45 HOH HOH A . Q 6 HOH 45 4046 46 HOH HOH A . Q 6 HOH 46 4047 47 HOH HOH A . Q 6 HOH 47 4048 48 HOH HOH A . Q 6 HOH 48 4049 49 HOH HOH A . Q 6 HOH 49 4050 50 HOH HOH A . Q 6 HOH 50 4051 51 HOH HOH A . Q 6 HOH 51 4052 52 HOH HOH A . Q 6 HOH 52 4053 53 HOH HOH A . Q 6 HOH 53 4054 55 HOH HOH A . Q 6 HOH 54 4055 56 HOH HOH A . Q 6 HOH 55 4056 57 HOH HOH A . Q 6 HOH 56 4057 58 HOH HOH A . Q 6 HOH 57 4058 59 HOH HOH A . Q 6 HOH 58 4059 60 HOH HOH A . Q 6 HOH 59 4060 61 HOH HOH A . Q 6 HOH 60 4061 62 HOH HOH A . Q 6 HOH 61 4062 63 HOH HOH A . Q 6 HOH 62 4063 64 HOH HOH A . Q 6 HOH 63 4064 66 HOH HOH A . Q 6 HOH 64 4065 67 HOH HOH A . Q 6 HOH 65 4066 68 HOH HOH A . Q 6 HOH 66 4067 69 HOH HOH A . Q 6 HOH 67 4068 70 HOH HOH A . Q 6 HOH 68 4069 72 HOH HOH A . Q 6 HOH 69 4070 73 HOH HOH A . Q 6 HOH 70 4071 75 HOH HOH A . Q 6 HOH 71 4072 76 HOH HOH A . Q 6 HOH 72 4073 77 HOH HOH A . Q 6 HOH 73 4074 78 HOH HOH A . Q 6 HOH 74 4075 79 HOH HOH A . Q 6 HOH 75 4076 80 HOH HOH A . Q 6 HOH 76 4077 81 HOH HOH A . Q 6 HOH 77 4078 82 HOH HOH A . Q 6 HOH 78 4079 83 HOH HOH A . Q 6 HOH 79 4080 84 HOH HOH A . Q 6 HOH 80 4081 85 HOH HOH A . Q 6 HOH 81 4082 86 HOH HOH A . Q 6 HOH 82 4083 87 HOH HOH A . Q 6 HOH 83 4084 88 HOH HOH A . Q 6 HOH 84 4085 89 HOH HOH A . Q 6 HOH 85 4086 90 HOH HOH A . Q 6 HOH 86 4087 91 HOH HOH A . Q 6 HOH 87 4088 93 HOH HOH A . Q 6 HOH 88 4089 94 HOH HOH A . Q 6 HOH 89 4090 95 HOH HOH A . Q 6 HOH 90 4091 96 HOH HOH A . Q 6 HOH 91 4092 97 HOH HOH A . Q 6 HOH 92 4093 98 HOH HOH A . Q 6 HOH 93 4094 99 HOH HOH A . Q 6 HOH 94 4095 100 HOH HOH A . Q 6 HOH 95 4096 101 HOH HOH A . Q 6 HOH 96 4097 102 HOH HOH A . Q 6 HOH 97 4098 103 HOH HOH A . Q 6 HOH 98 4099 104 HOH HOH A . Q 6 HOH 99 4100 105 HOH HOH A . Q 6 HOH 100 4101 107 HOH HOH A . Q 6 HOH 101 4102 108 HOH HOH A . Q 6 HOH 102 4103 109 HOH HOH A . Q 6 HOH 103 4104 111 HOH HOH A . Q 6 HOH 104 4105 112 HOH HOH A . Q 6 HOH 105 4106 114 HOH HOH A . Q 6 HOH 106 4107 115 HOH HOH A . Q 6 HOH 107 4108 116 HOH HOH A . Q 6 HOH 108 4109 118 HOH HOH A . Q 6 HOH 109 4110 120 HOH HOH A . Q 6 HOH 110 4111 121 HOH HOH A . Q 6 HOH 111 4112 122 HOH HOH A . Q 6 HOH 112 4113 123 HOH HOH A . Q 6 HOH 113 4114 124 HOH HOH A . Q 6 HOH 114 4115 125 HOH HOH A . Q 6 HOH 115 4116 126 HOH HOH A . Q 6 HOH 116 4117 127 HOH HOH A . Q 6 HOH 117 4118 128 HOH HOH A . Q 6 HOH 118 4119 129 HOH HOH A . Q 6 HOH 119 4120 130 HOH HOH A . Q 6 HOH 120 4121 131 HOH HOH A . Q 6 HOH 121 4122 132 HOH HOH A . Q 6 HOH 122 4123 133 HOH HOH A . Q 6 HOH 123 4124 134 HOH HOH A . Q 6 HOH 124 4125 135 HOH HOH A . Q 6 HOH 125 4126 136 HOH HOH A . Q 6 HOH 126 4127 137 HOH HOH A . Q 6 HOH 127 4128 138 HOH HOH A . Q 6 HOH 128 4129 139 HOH HOH A . Q 6 HOH 129 4130 140 HOH HOH A . Q 6 HOH 130 4131 141 HOH HOH A . Q 6 HOH 131 4132 142 HOH HOH A . Q 6 HOH 132 4133 143 HOH HOH A . Q 6 HOH 133 4134 144 HOH HOH A . Q 6 HOH 134 4135 145 HOH HOH A . Q 6 HOH 135 4136 146 HOH HOH A . Q 6 HOH 136 4137 147 HOH HOH A . Q 6 HOH 137 4138 148 HOH HOH A . Q 6 HOH 138 4139 149 HOH HOH A . Q 6 HOH 139 4140 150 HOH HOH A . Q 6 HOH 140 4141 151 HOH HOH A . Q 6 HOH 141 4142 152 HOH HOH A . Q 6 HOH 142 4143 154 HOH HOH A . Q 6 HOH 143 4144 157 HOH HOH A . Q 6 HOH 144 4145 158 HOH HOH A . Q 6 HOH 145 4146 159 HOH HOH A . Q 6 HOH 146 4147 160 HOH HOH A . Q 6 HOH 147 4148 161 HOH HOH A . Q 6 HOH 148 4149 162 HOH HOH A . Q 6 HOH 149 4150 163 HOH HOH A . Q 6 HOH 150 4151 164 HOH HOH A . Q 6 HOH 151 4152 165 HOH HOH A . Q 6 HOH 152 4153 166 HOH HOH A . Q 6 HOH 153 4154 167 HOH HOH A . Q 6 HOH 154 4155 168 HOH HOH A . Q 6 HOH 155 4156 169 HOH HOH A . Q 6 HOH 156 4157 170 HOH HOH A . Q 6 HOH 157 4158 171 HOH HOH A . Q 6 HOH 158 4159 172 HOH HOH A . Q 6 HOH 159 4160 173 HOH HOH A . Q 6 HOH 160 4161 175 HOH HOH A . Q 6 HOH 161 4162 177 HOH HOH A . Q 6 HOH 162 4163 178 HOH HOH A . Q 6 HOH 163 4164 179 HOH HOH A . Q 6 HOH 164 4165 180 HOH HOH A . Q 6 HOH 165 4166 182 HOH HOH A . Q 6 HOH 166 4167 184 HOH HOH A . Q 6 HOH 167 4168 185 HOH HOH A . Q 6 HOH 168 4169 187 HOH HOH A . Q 6 HOH 169 4170 188 HOH HOH A . Q 6 HOH 170 4171 189 HOH HOH A . Q 6 HOH 171 4172 190 HOH HOH A . Q 6 HOH 172 4173 191 HOH HOH A . Q 6 HOH 173 4174 192 HOH HOH A . Q 6 HOH 174 4175 193 HOH HOH A . Q 6 HOH 175 4176 194 HOH HOH A . Q 6 HOH 176 4177 195 HOH HOH A . Q 6 HOH 177 4178 196 HOH HOH A . Q 6 HOH 178 4179 197 HOH HOH A . Q 6 HOH 179 4180 198 HOH HOH A . Q 6 HOH 180 4181 199 HOH HOH A . Q 6 HOH 181 4182 200 HOH HOH A . Q 6 HOH 182 4183 201 HOH HOH A . Q 6 HOH 183 4184 202 HOH HOH A . Q 6 HOH 184 4185 203 HOH HOH A . Q 6 HOH 185 4186 204 HOH HOH A . Q 6 HOH 186 4187 206 HOH HOH A . Q 6 HOH 187 4188 207 HOH HOH A . Q 6 HOH 188 4189 208 HOH HOH A . Q 6 HOH 189 4190 209 HOH HOH A . Q 6 HOH 190 4191 211 HOH HOH A . Q 6 HOH 191 4192 213 HOH HOH A . Q 6 HOH 192 4193 214 HOH HOH A . Q 6 HOH 193 4194 215 HOH HOH A . Q 6 HOH 194 4195 216 HOH HOH A . Q 6 HOH 195 4196 217 HOH HOH A . Q 6 HOH 196 4197 218 HOH HOH A . Q 6 HOH 197 4198 219 HOH HOH A . Q 6 HOH 198 4199 220 HOH HOH A . Q 6 HOH 199 4200 221 HOH HOH A . Q 6 HOH 200 4201 222 HOH HOH A . Q 6 HOH 201 4202 223 HOH HOH A . Q 6 HOH 202 4203 225 HOH HOH A . Q 6 HOH 203 4204 226 HOH HOH A . Q 6 HOH 204 4205 227 HOH HOH A . Q 6 HOH 205 4206 228 HOH HOH A . Q 6 HOH 206 4207 229 HOH HOH A . Q 6 HOH 207 4208 230 HOH HOH A . Q 6 HOH 208 4209 232 HOH HOH A . Q 6 HOH 209 4210 233 HOH HOH A . Q 6 HOH 210 4211 234 HOH HOH A . Q 6 HOH 211 4212 237 HOH HOH A . Q 6 HOH 212 4213 238 HOH HOH A . Q 6 HOH 213 4214 239 HOH HOH A . Q 6 HOH 214 4215 240 HOH HOH A . Q 6 HOH 215 4216 241 HOH HOH A . Q 6 HOH 216 4217 242 HOH HOH A . Q 6 HOH 217 4218 244 HOH HOH A . Q 6 HOH 218 4219 245 HOH HOH A . Q 6 HOH 219 4220 246 HOH HOH A . Q 6 HOH 220 4221 247 HOH HOH A . Q 6 HOH 221 4222 248 HOH HOH A . Q 6 HOH 222 4223 249 HOH HOH A . Q 6 HOH 223 4224 250 HOH HOH A . Q 6 HOH 224 4225 251 HOH HOH A . Q 6 HOH 225 4226 252 HOH HOH A . Q 6 HOH 226 4227 255 HOH HOH A . Q 6 HOH 227 4228 256 HOH HOH A . Q 6 HOH 228 4229 257 HOH HOH A . Q 6 HOH 229 4230 258 HOH HOH A . Q 6 HOH 230 4231 259 HOH HOH A . Q 6 HOH 231 4232 260 HOH HOH A . Q 6 HOH 232 4233 261 HOH HOH A . Q 6 HOH 233 4234 262 HOH HOH A . Q 6 HOH 234 4235 263 HOH HOH A . Q 6 HOH 235 4236 264 HOH HOH A . Q 6 HOH 236 4237 265 HOH HOH A . Q 6 HOH 237 4238 266 HOH HOH A . Q 6 HOH 238 4239 267 HOH HOH A . Q 6 HOH 239 4240 269 HOH HOH A . Q 6 HOH 240 4241 271 HOH HOH A . Q 6 HOH 241 4242 272 HOH HOH A . Q 6 HOH 242 4243 273 HOH HOH A . Q 6 HOH 243 4244 275 HOH HOH A . Q 6 HOH 244 4245 276 HOH HOH A . Q 6 HOH 245 4246 277 HOH HOH A . Q 6 HOH 246 4247 278 HOH HOH A . Q 6 HOH 247 4248 279 HOH HOH A . Q 6 HOH 248 4249 280 HOH HOH A . Q 6 HOH 249 4250 281 HOH HOH A . Q 6 HOH 250 4251 282 HOH HOH A . Q 6 HOH 251 4252 283 HOH HOH A . Q 6 HOH 252 4253 284 HOH HOH A . Q 6 HOH 253 4254 285 HOH HOH A . Q 6 HOH 254 4255 286 HOH HOH A . Q 6 HOH 255 4256 287 HOH HOH A . Q 6 HOH 256 4257 288 HOH HOH A . Q 6 HOH 257 4258 289 HOH HOH A . Q 6 HOH 258 4259 290 HOH HOH A . Q 6 HOH 259 4260 291 HOH HOH A . Q 6 HOH 260 4261 292 HOH HOH A . Q 6 HOH 261 4262 294 HOH HOH A . Q 6 HOH 262 4263 295 HOH HOH A . Q 6 HOH 263 4264 296 HOH HOH A . Q 6 HOH 264 4265 297 HOH HOH A . Q 6 HOH 265 4266 298 HOH HOH A . Q 6 HOH 266 4267 299 HOH HOH A . Q 6 HOH 267 4268 301 HOH HOH A . Q 6 HOH 268 4269 302 HOH HOH A . Q 6 HOH 269 4270 303 HOH HOH A . Q 6 HOH 270 4271 306 HOH HOH A . Q 6 HOH 271 4272 307 HOH HOH A . Q 6 HOH 272 4273 308 HOH HOH A . Q 6 HOH 273 4274 309 HOH HOH A . Q 6 HOH 274 4275 310 HOH HOH A . Q 6 HOH 275 4276 311 HOH HOH A . Q 6 HOH 276 4277 312 HOH HOH A . Q 6 HOH 277 4278 313 HOH HOH A . Q 6 HOH 278 4279 315 HOH HOH A . Q 6 HOH 279 4280 316 HOH HOH A . Q 6 HOH 280 4281 317 HOH HOH A . Q 6 HOH 281 4282 318 HOH HOH A . Q 6 HOH 282 4283 319 HOH HOH A . Q 6 HOH 283 4284 320 HOH HOH A . Q 6 HOH 284 4285 321 HOH HOH A . Q 6 HOH 285 4286 322 HOH HOH A . Q 6 HOH 286 4287 323 HOH HOH A . Q 6 HOH 287 4288 324 HOH HOH A . Q 6 HOH 288 4289 325 HOH HOH A . Q 6 HOH 289 4290 326 HOH HOH A . Q 6 HOH 290 4291 327 HOH HOH A . Q 6 HOH 291 4292 328 HOH HOH A . Q 6 HOH 292 4293 329 HOH HOH A . Q 6 HOH 293 4294 331 HOH HOH A . Q 6 HOH 294 4295 332 HOH HOH A . Q 6 HOH 295 4296 333 HOH HOH A . Q 6 HOH 296 4297 334 HOH HOH A . Q 6 HOH 297 4298 335 HOH HOH A . Q 6 HOH 298 4299 336 HOH HOH A . Q 6 HOH 299 4300 337 HOH HOH A . Q 6 HOH 300 4301 338 HOH HOH A . Q 6 HOH 301 4302 339 HOH HOH A . Q 6 HOH 302 4303 340 HOH HOH A . Q 6 HOH 303 4304 341 HOH HOH A . Q 6 HOH 304 4305 342 HOH HOH A . Q 6 HOH 305 4306 343 HOH HOH A . Q 6 HOH 306 4307 345 HOH HOH A . Q 6 HOH 307 4308 346 HOH HOH A . Q 6 HOH 308 4309 347 HOH HOH A . Q 6 HOH 309 4310 348 HOH HOH A . Q 6 HOH 310 4311 349 HOH HOH A . Q 6 HOH 311 4312 350 HOH HOH A . Q 6 HOH 312 4313 351 HOH HOH A . Q 6 HOH 313 4314 352 HOH HOH A . Q 6 HOH 314 4315 353 HOH HOH A . Q 6 HOH 315 4316 354 HOH HOH A . Q 6 HOH 316 4317 356 HOH HOH A . Q 6 HOH 317 4318 357 HOH HOH A . Q 6 HOH 318 4319 358 HOH HOH A . Q 6 HOH 319 4320 359 HOH HOH A . Q 6 HOH 320 4321 360 HOH HOH A . Q 6 HOH 321 4322 361 HOH HOH A . Q 6 HOH 322 4323 362 HOH HOH A . Q 6 HOH 323 4324 363 HOH HOH A . Q 6 HOH 324 4325 364 HOH HOH A . Q 6 HOH 325 4326 365 HOH HOH A . Q 6 HOH 326 4327 366 HOH HOH A . Q 6 HOH 327 4328 367 HOH HOH A . Q 6 HOH 328 4329 368 HOH HOH A . Q 6 HOH 329 4330 369 HOH HOH A . Q 6 HOH 330 4331 370 HOH HOH A . Q 6 HOH 331 4332 371 HOH HOH A . Q 6 HOH 332 4333 372 HOH HOH A . Q 6 HOH 333 4334 373 HOH HOH A . Q 6 HOH 334 4335 374 HOH HOH A . Q 6 HOH 335 4336 375 HOH HOH A . Q 6 HOH 336 4337 376 HOH HOH A . Q 6 HOH 337 4338 377 HOH HOH A . Q 6 HOH 338 4339 379 HOH HOH A . Q 6 HOH 339 4340 382 HOH HOH A . Q 6 HOH 340 4341 383 HOH HOH A . Q 6 HOH 341 4342 384 HOH HOH A . Q 6 HOH 342 4343 385 HOH HOH A . Q 6 HOH 343 4344 386 HOH HOH A . Q 6 HOH 344 4345 387 HOH HOH A . Q 6 HOH 345 4346 388 HOH HOH A . Q 6 HOH 346 4347 389 HOH HOH A . Q 6 HOH 347 4348 390 HOH HOH A . Q 6 HOH 348 4349 391 HOH HOH A . Q 6 HOH 349 4350 392 HOH HOH A . Q 6 HOH 350 4351 393 HOH HOH A . Q 6 HOH 351 4352 395 HOH HOH A . Q 6 HOH 352 4353 396 HOH HOH A . Q 6 HOH 353 4354 397 HOH HOH A . Q 6 HOH 354 4355 398 HOH HOH A . Q 6 HOH 355 4356 399 HOH HOH A . Q 6 HOH 356 4357 400 HOH HOH A . Q 6 HOH 357 4358 402 HOH HOH A . Q 6 HOH 358 4359 403 HOH HOH A . Q 6 HOH 359 4360 404 HOH HOH A . Q 6 HOH 360 4361 405 HOH HOH A . Q 6 HOH 361 4362 406 HOH HOH A . Q 6 HOH 362 4363 407 HOH HOH A . Q 6 HOH 363 4364 408 HOH HOH A . Q 6 HOH 364 4365 409 HOH HOH A . Q 6 HOH 365 4366 410 HOH HOH A . Q 6 HOH 366 4367 411 HOH HOH A . Q 6 HOH 367 4368 413 HOH HOH A . Q 6 HOH 368 4369 414 HOH HOH A . Q 6 HOH 369 4370 415 HOH HOH A . Q 6 HOH 370 4371 416 HOH HOH A . Q 6 HOH 371 4372 417 HOH HOH A . Q 6 HOH 372 4373 419 HOH HOH A . Q 6 HOH 373 4374 420 HOH HOH A . Q 6 HOH 374 4375 421 HOH HOH A . Q 6 HOH 375 4376 422 HOH HOH A . Q 6 HOH 376 4377 423 HOH HOH A . Q 6 HOH 377 4378 424 HOH HOH A . Q 6 HOH 378 4379 425 HOH HOH A . Q 6 HOH 379 4380 426 HOH HOH A . Q 6 HOH 380 4381 427 HOH HOH A . Q 6 HOH 381 4382 428 HOH HOH A . Q 6 HOH 382 4383 429 HOH HOH A . Q 6 HOH 383 4384 431 HOH HOH A . Q 6 HOH 384 4385 432 HOH HOH A . Q 6 HOH 385 4386 433 HOH HOH A . Q 6 HOH 386 4387 435 HOH HOH A . Q 6 HOH 387 4388 436 HOH HOH A . Q 6 HOH 388 4389 437 HOH HOH A . Q 6 HOH 389 4390 438 HOH HOH A . Q 6 HOH 390 4391 441 HOH HOH A . Q 6 HOH 391 4392 442 HOH HOH A . Q 6 HOH 392 4393 443 HOH HOH A . Q 6 HOH 393 4394 444 HOH HOH A . Q 6 HOH 394 4395 445 HOH HOH A . Q 6 HOH 395 4396 446 HOH HOH A . Q 6 HOH 396 4397 447 HOH HOH A . Q 6 HOH 397 4398 448 HOH HOH A . Q 6 HOH 398 4399 449 HOH HOH A . Q 6 HOH 399 4400 450 HOH HOH A . Q 6 HOH 400 4401 451 HOH HOH A . Q 6 HOH 401 4402 453 HOH HOH A . Q 6 HOH 402 4403 454 HOH HOH A . Q 6 HOH 403 4404 455 HOH HOH A . Q 6 HOH 404 4405 456 HOH HOH A . Q 6 HOH 405 4406 457 HOH HOH A . Q 6 HOH 406 4407 458 HOH HOH A . Q 6 HOH 407 4408 459 HOH HOH A . Q 6 HOH 408 4409 460 HOH HOH A . Q 6 HOH 409 4410 461 HOH HOH A . Q 6 HOH 410 4411 462 HOH HOH A . Q 6 HOH 411 4412 463 HOH HOH A . Q 6 HOH 412 4413 464 HOH HOH A . Q 6 HOH 413 4414 465 HOH HOH A . Q 6 HOH 414 4415 466 HOH HOH A . Q 6 HOH 415 4416 467 HOH HOH A . Q 6 HOH 416 4417 468 HOH HOH A . Q 6 HOH 417 4418 470 HOH HOH A . Q 6 HOH 418 4419 472 HOH HOH A . Q 6 HOH 419 4420 473 HOH HOH A . Q 6 HOH 420 4421 474 HOH HOH A . Q 6 HOH 421 4422 475 HOH HOH A . Q 6 HOH 422 4423 476 HOH HOH A . Q 6 HOH 423 4424 477 HOH HOH A . Q 6 HOH 424 4425 478 HOH HOH A . Q 6 HOH 425 4426 479 HOH HOH A . Q 6 HOH 426 4427 480 HOH HOH A . Q 6 HOH 427 4428 481 HOH HOH A . Q 6 HOH 428 4429 482 HOH HOH A . Q 6 HOH 429 4430 483 HOH HOH A . Q 6 HOH 430 4431 484 HOH HOH A . Q 6 HOH 431 4432 485 HOH HOH A . Q 6 HOH 432 4433 486 HOH HOH A . Q 6 HOH 433 4434 487 HOH HOH A . Q 6 HOH 434 4435 488 HOH HOH A . Q 6 HOH 435 4436 489 HOH HOH A . Q 6 HOH 436 4437 490 HOH HOH A . Q 6 HOH 437 4438 491 HOH HOH A . Q 6 HOH 438 4439 492 HOH HOH A . Q 6 HOH 439 4440 493 HOH HOH A . Q 6 HOH 440 4441 494 HOH HOH A . Q 6 HOH 441 4442 495 HOH HOH A . Q 6 HOH 442 4443 496 HOH HOH A . Q 6 HOH 443 4444 497 HOH HOH A . Q 6 HOH 444 4445 498 HOH HOH A . Q 6 HOH 445 4446 499 HOH HOH A . Q 6 HOH 446 4447 500 HOH HOH A . Q 6 HOH 447 4448 501 HOH HOH A . Q 6 HOH 448 4449 502 HOH HOH A . Q 6 HOH 449 4450 503 HOH HOH A . Q 6 HOH 450 4451 504 HOH HOH A . Q 6 HOH 451 4452 505 HOH HOH A . Q 6 HOH 452 4453 506 HOH HOH A . Q 6 HOH 453 4454 507 HOH HOH A . Q 6 HOH 454 4455 508 HOH HOH A . Q 6 HOH 455 4456 509 HOH HOH A . Q 6 HOH 456 4457 510 HOH HOH A . Q 6 HOH 457 4458 513 HOH HOH A . Q 6 HOH 458 4459 515 HOH HOH A . Q 6 HOH 459 4460 516 HOH HOH A . Q 6 HOH 460 4461 517 HOH HOH A . Q 6 HOH 461 4462 518 HOH HOH A . Q 6 HOH 462 4463 519 HOH HOH A . Q 6 HOH 463 4464 521 HOH HOH A . Q 6 HOH 464 4465 522 HOH HOH A . Q 6 HOH 465 4466 525 HOH HOH A . Q 6 HOH 466 4467 526 HOH HOH A . Q 6 HOH 467 4468 527 HOH HOH A . Q 6 HOH 468 4469 528 HOH HOH A . Q 6 HOH 469 4470 529 HOH HOH A . Q 6 HOH 470 4471 530 HOH HOH A . Q 6 HOH 471 4472 531 HOH HOH A . Q 6 HOH 472 4473 532 HOH HOH A . Q 6 HOH 473 4474 533 HOH HOH A . Q 6 HOH 474 4475 534 HOH HOH A . Q 6 HOH 475 4476 535 HOH HOH A . Q 6 HOH 476 4477 536 HOH HOH A . Q 6 HOH 477 4478 537 HOH HOH A . Q 6 HOH 478 4479 538 HOH HOH A . Q 6 HOH 479 4480 539 HOH HOH A . Q 6 HOH 480 4481 540 HOH HOH A . Q 6 HOH 481 4482 541 HOH HOH A . Q 6 HOH 482 4483 542 HOH HOH A . Q 6 HOH 483 4484 543 HOH HOH A . Q 6 HOH 484 4485 544 HOH HOH A . Q 6 HOH 485 4486 545 HOH HOH A . Q 6 HOH 486 4487 546 HOH HOH A . Q 6 HOH 487 4488 547 HOH HOH A . Q 6 HOH 488 4489 548 HOH HOH A . Q 6 HOH 489 4490 552 HOH HOH A . Q 6 HOH 490 4491 553 HOH HOH A . Q 6 HOH 491 4492 554 HOH HOH A . Q 6 HOH 492 4493 556 HOH HOH A . Q 6 HOH 493 4494 557 HOH HOH A . Q 6 HOH 494 4495 558 HOH HOH A . Q 6 HOH 495 4496 559 HOH HOH A . Q 6 HOH 496 4497 560 HOH HOH A . Q 6 HOH 497 4498 561 HOH HOH A . Q 6 HOH 498 4499 562 HOH HOH A . Q 6 HOH 499 4500 563 HOH HOH A . Q 6 HOH 500 4501 564 HOH HOH A . Q 6 HOH 501 4502 565 HOH HOH A . Q 6 HOH 502 4503 566 HOH HOH A . Q 6 HOH 503 4504 567 HOH HOH A . Q 6 HOH 504 4505 568 HOH HOH A . Q 6 HOH 505 4506 569 HOH HOH A . Q 6 HOH 506 4507 570 HOH HOH A . Q 6 HOH 507 4508 571 HOH HOH A . Q 6 HOH 508 4509 572 HOH HOH A . Q 6 HOH 509 4510 573 HOH HOH A . Q 6 HOH 510 4511 574 HOH HOH A . Q 6 HOH 511 4512 575 HOH HOH A . Q 6 HOH 512 4513 576 HOH HOH A . Q 6 HOH 513 4514 577 HOH HOH A . Q 6 HOH 514 4515 579 HOH HOH A . Q 6 HOH 515 4516 580 HOH HOH A . Q 6 HOH 516 4517 582 HOH HOH A . Q 6 HOH 517 4518 583 HOH HOH A . Q 6 HOH 518 4519 585 HOH HOH A . Q 6 HOH 519 4520 586 HOH HOH A . Q 6 HOH 520 4521 587 HOH HOH A . Q 6 HOH 521 4522 588 HOH HOH A . Q 6 HOH 522 4523 589 HOH HOH A . Q 6 HOH 523 4524 592 HOH HOH A . Q 6 HOH 524 4525 593 HOH HOH A . Q 6 HOH 525 4526 594 HOH HOH A . Q 6 HOH 526 4527 595 HOH HOH A . Q 6 HOH 527 4528 596 HOH HOH A . Q 6 HOH 528 4529 597 HOH HOH A . Q 6 HOH 529 4530 599 HOH HOH A . Q 6 HOH 530 4531 601 HOH HOH A . Q 6 HOH 531 4532 602 HOH HOH A . Q 6 HOH 532 4533 603 HOH HOH A . Q 6 HOH 533 4534 604 HOH HOH A . Q 6 HOH 534 4535 605 HOH HOH A . Q 6 HOH 535 4536 606 HOH HOH A . Q 6 HOH 536 4537 607 HOH HOH A . Q 6 HOH 537 4538 608 HOH HOH A . Q 6 HOH 538 4539 611 HOH HOH A . Q 6 HOH 539 4540 612 HOH HOH A . Q 6 HOH 540 4541 613 HOH HOH A . Q 6 HOH 541 4542 614 HOH HOH A . Q 6 HOH 542 4543 615 HOH HOH A . Q 6 HOH 543 4544 616 HOH HOH A . Q 6 HOH 544 4545 617 HOH HOH A . Q 6 HOH 545 4546 618 HOH HOH A . Q 6 HOH 546 4547 623 HOH HOH A . Q 6 HOH 547 4548 624 HOH HOH A . Q 6 HOH 548 4549 625 HOH HOH A . Q 6 HOH 549 4550 626 HOH HOH A . Q 6 HOH 550 4551 627 HOH HOH A . Q 6 HOH 551 4552 628 HOH HOH A . Q 6 HOH 552 4553 629 HOH HOH A . Q 6 HOH 553 4554 630 HOH HOH A . Q 6 HOH 554 4555 631 HOH HOH A . Q 6 HOH 555 4556 632 HOH HOH A . Q 6 HOH 556 4557 633 HOH HOH A . Q 6 HOH 557 4558 634 HOH HOH A . Q 6 HOH 558 4559 635 HOH HOH A . Q 6 HOH 559 4560 636 HOH HOH A . Q 6 HOH 560 4561 637 HOH HOH A . Q 6 HOH 561 4562 638 HOH HOH A . Q 6 HOH 562 4563 639 HOH HOH A . Q 6 HOH 563 4564 640 HOH HOH A . Q 6 HOH 564 4565 641 HOH HOH A . Q 6 HOH 565 4566 642 HOH HOH A . Q 6 HOH 566 4567 643 HOH HOH A . Q 6 HOH 567 4568 646 HOH HOH A . Q 6 HOH 568 4569 653 HOH HOH A . Q 6 HOH 569 4570 656 HOH HOH A . Q 6 HOH 570 4571 657 HOH HOH A . Q 6 HOH 571 4572 658 HOH HOH A . Q 6 HOH 572 4573 659 HOH HOH A . Q 6 HOH 573 4574 660 HOH HOH A . Q 6 HOH 574 4575 661 HOH HOH A . Q 6 HOH 575 4576 662 HOH HOH A . Q 6 HOH 576 4577 663 HOH HOH A . Q 6 HOH 577 4578 665 HOH HOH A . Q 6 HOH 578 4579 666 HOH HOH A . Q 6 HOH 579 4580 667 HOH HOH A . Q 6 HOH 580 4581 668 HOH HOH A . Q 6 HOH 581 4582 669 HOH HOH A . Q 6 HOH 582 4583 670 HOH HOH A . Q 6 HOH 583 4584 671 HOH HOH A . Q 6 HOH 584 4585 672 HOH HOH A . Q 6 HOH 585 4586 673 HOH HOH A . Q 6 HOH 586 4587 674 HOH HOH A . Q 6 HOH 587 4588 677 HOH HOH A . Q 6 HOH 588 4589 678 HOH HOH A . Q 6 HOH 589 4590 679 HOH HOH A . Q 6 HOH 590 4591 681 HOH HOH A . Q 6 HOH 591 4592 684 HOH HOH A . Q 6 HOH 592 4593 687 HOH HOH A . Q 6 HOH 593 4594 689 HOH HOH A . Q 6 HOH 594 4595 692 HOH HOH A . Q 6 HOH 595 4596 693 HOH HOH A . Q 6 HOH 596 4597 694 HOH HOH A . Q 6 HOH 597 4598 696 HOH HOH A . Q 6 HOH 598 4599 697 HOH HOH A . Q 6 HOH 599 4600 698 HOH HOH A . Q 6 HOH 600 4601 700 HOH HOH A . Q 6 HOH 601 4602 701 HOH HOH A . Q 6 HOH 602 4603 702 HOH HOH A . Q 6 HOH 603 4604 703 HOH HOH A . Q 6 HOH 604 4605 705 HOH HOH A . Q 6 HOH 605 4606 706 HOH HOH A . Q 6 HOH 606 4607 707 HOH HOH A . Q 6 HOH 607 4608 709 HOH HOH A . Q 6 HOH 608 4609 710 HOH HOH A . Q 6 HOH 609 4610 713 HOH HOH A . Q 6 HOH 610 4611 714 HOH HOH A . Q 6 HOH 611 4612 715 HOH HOH A . Q 6 HOH 612 4613 717 HOH HOH A . Q 6 HOH 613 4614 718 HOH HOH A . Q 6 HOH 614 4615 721 HOH HOH A . Q 6 HOH 615 4616 723 HOH HOH A . Q 6 HOH 616 4617 724 HOH HOH A . Q 6 HOH 617 4618 725 HOH HOH A . Q 6 HOH 618 4619 726 HOH HOH A . Q 6 HOH 619 4620 727 HOH HOH A . Q 6 HOH 620 4621 728 HOH HOH A . Q 6 HOH 621 4622 355 HOH HOH A . Q 6 HOH 622 4623 418 HOH HOH A . Q 6 HOH 623 4624 471 HOH HOH A . Q 6 HOH 624 4625 591 HOH HOH A . Q 6 HOH 625 4626 729 HOH HOH A . Q 6 HOH 626 4627 730 HOH HOH A . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 209 A ASN 209 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 393 A ASN 393 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 741 A ASN 741 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_and_software_defined_assembly _pdbx_struct_assembly.method_details PISA _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2008-01-08 2 'Structure model' 1 1 2011-07-13 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Non-polymer description' 2 2 'Structure model' 'Version format compliance' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal REFMAC refinement 5.2.0019 ? 1 HKL-2000 'data collection' . ? 2 HKL-2000 'data reduction' . ? 3 HKL-2000 'data scaling' . ? 4 PHASER phasing . ? 5 # _pdbx_validate_rmsd_angle.id 1 _pdbx_validate_rmsd_angle.PDB_model_num 1 _pdbx_validate_rmsd_angle.auth_atom_id_1 NE _pdbx_validate_rmsd_angle.auth_asym_id_1 A _pdbx_validate_rmsd_angle.auth_comp_id_1 ARG _pdbx_validate_rmsd_angle.auth_seq_id_1 624 _pdbx_validate_rmsd_angle.PDB_ins_code_1 ? _pdbx_validate_rmsd_angle.label_alt_id_1 ? _pdbx_validate_rmsd_angle.auth_atom_id_2 CZ _pdbx_validate_rmsd_angle.auth_asym_id_2 A _pdbx_validate_rmsd_angle.auth_comp_id_2 ARG _pdbx_validate_rmsd_angle.auth_seq_id_2 624 _pdbx_validate_rmsd_angle.PDB_ins_code_2 ? _pdbx_validate_rmsd_angle.label_alt_id_2 ? _pdbx_validate_rmsd_angle.auth_atom_id_3 NH2 _pdbx_validate_rmsd_angle.auth_asym_id_3 A _pdbx_validate_rmsd_angle.auth_comp_id_3 ARG _pdbx_validate_rmsd_angle.auth_seq_id_3 624 _pdbx_validate_rmsd_angle.PDB_ins_code_3 ? _pdbx_validate_rmsd_angle.label_alt_id_3 ? _pdbx_validate_rmsd_angle.angle_value 117.00 _pdbx_validate_rmsd_angle.angle_target_value 120.30 _pdbx_validate_rmsd_angle.angle_deviation -3.30 _pdbx_validate_rmsd_angle.angle_standard_deviation 0.50 _pdbx_validate_rmsd_angle.linker_flag N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASN A 8 ? ? -36.09 128.07 2 1 ASN A 34 ? ? -155.98 87.54 3 1 SER A 40 ? ? 75.14 -11.82 4 1 HIS A 50 ? ? -143.87 -38.34 5 1 SER A 51 ? ? -103.03 -107.77 6 1 SER A 80 ? ? -47.56 86.16 7 1 PHE A 161 ? ? -150.53 82.42 8 1 LEU A 180 ? ? 70.62 146.30 9 1 GLN A 186 ? ? 70.61 -30.85 10 1 TRP A 194 ? ? 53.77 75.28 11 1 PHE A 200 ? ? -170.49 116.33 12 1 ASN A 207 ? ? -124.06 -162.23 13 1 LEU A 213 ? ? -124.18 -149.53 14 1 GLU A 300 ? ? 68.29 65.28 15 1 TYR A 321 ? ? -169.10 97.14 16 1 VAL A 342 ? ? -96.23 -63.01 17 1 VAL A 405 ? ? -134.40 -148.97 18 1 ASP A 474 ? ? 82.41 -15.98 19 1 SER A 521 ? ? 56.96 -144.31 20 1 ILE A 565 ? ? -117.58 72.58 21 1 CYS A 573 ? ? 85.17 -21.20 22 1 PHE A 575 ? ? -63.88 -71.93 23 1 LEU A 577 ? ? 86.93 152.27 24 1 VAL A 651 ? ? -107.16 -70.32 25 1 GLU A 774 ? ? -153.03 -21.94 26 1 GLN A 793 ? ? 3.29 119.99 27 1 SER A 803 ? ? -143.27 48.63 # _pdbx_validate_peptide_omega.id 1 _pdbx_validate_peptide_omega.PDB_model_num 1 _pdbx_validate_peptide_omega.auth_comp_id_1 GLU _pdbx_validate_peptide_omega.auth_asym_id_1 A _pdbx_validate_peptide_omega.auth_seq_id_1 300 _pdbx_validate_peptide_omega.PDB_ins_code_1 ? _pdbx_validate_peptide_omega.label_alt_id_1 ? _pdbx_validate_peptide_omega.auth_comp_id_2 TYR _pdbx_validate_peptide_omega.auth_asym_id_2 A _pdbx_validate_peptide_omega.auth_seq_id_2 301 _pdbx_validate_peptide_omega.PDB_ins_code_2 ? _pdbx_validate_peptide_omega.label_alt_id_2 ? _pdbx_validate_peptide_omega.omega 149.74 # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A SER 1 ? A SER 1 2 1 Y 1 A ALA 2 ? A ALA 2 3 1 Y 1 A GLU 3 ? A GLU 3 4 1 Y 1 A CYS 4 ? A CYS 4 5 1 Y 1 A PRO 5 ? A PRO 5 6 1 Y 1 A VAL 6 ? A VAL 6 7 1 Y 1 A GLN 837 ? A GLN 837 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 ALPHA-ACARBOSE ACR 3 N-ACETYL-D-GLUCOSAMINE NAG 4 'SULFATE ION' SO4 5 GLYCEROL GOL 6 water HOH #