data_2IKC # _entry.id 2IKC # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.286 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2IKC RCSB RCSB039678 WWPDB D_1000039678 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 2GJ1 'Crystal structure of Bovine lactoperoxidase at 2.3A resolution' unspecified PDB 2GJM 'Crystal structure of Buffalo lactoperoxidase at 2.75A resolution' unspecified # _pdbx_database_status.status_code REL _pdbx_database_status.entry_id 2IKC _pdbx_database_status.recvd_initial_deposition_date 2006-10-02 _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site PDBJ _pdbx_database_status.status_code_sf ? _pdbx_database_status.status_code_mr ? _pdbx_database_status.SG_entry ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Sheikh, I.A.' 1 'Singh, N.' 2 'Singh, A.K.' 3 'Sharma, S.' 4 'Singh, T.P.' 5 # _citation.id primary _citation.title 'Crystal structure of sheep lactoperoxidase at 3.25 A resolution reveals the binding sites for formate' _citation.journal_abbrev 'To be Published' _citation.journal_volume ? _citation.page_first ? _citation.page_last ? _citation.year ? _citation.journal_id_ASTM ? _citation.country ? _citation.journal_id_ISSN ? _citation.journal_id_CSD 0353 _citation.book_publisher ? _citation.pdbx_database_id_PubMed ? _citation.pdbx_database_id_DOI ? # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Sheikh, I.A.' 1 primary 'Singh, N.' 2 primary 'Singh, A.K.' 3 primary 'Sharma, S.' 4 primary 'Singh, T.P.' 5 # _cell.entry_id 2IKC _cell.length_a 59.080 _cell.length_b 72.590 _cell.length_c 84.470 _cell.angle_alpha 85.20 _cell.angle_beta 84.07 _cell.angle_gamma 75.41 _cell.Z_PDB 2 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2IKC _symmetry.space_group_name_H-M 'P 1' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 1 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer nat 'milk lactoperoxidase' 67696.172 2 1.11.1.7 ? 'residues 1-595' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 14 ? ? ? ? 3 non-polymer man ALPHA-D-MANNOSE 180.156 2 ? ? ? ? 4 non-polymer syn 'CALCIUM ION' 40.078 2 ? ? ? ? 5 non-polymer syn 'CARBONATE ION' 60.009 2 ? ? ? ? 6 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE' 616.487 2 ? ? ? ? 7 non-polymer syn 'FORMIC ACID' 46.025 6 ? ? ? ? 8 water nat water 18.015 148 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Peroxidase, Airway lactoperoxidase' # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSN KIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPF FRAGFVCPTPPYQSLARDQINSVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNMKPSPCEFI NTTARVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEKLYQEARKILGAFIQIITFRDYLPIVLGSE MQKWIPRYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPRGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLL AKKSKLMNQNKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKILAKKL LDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHIT KVPLHAFQANNYPHDFVDCSAIDKLDLSPWASREN ; _entity_poly.pdbx_seq_one_letter_code_can ;SWEVGCGAPVPLVKCDENSPYRTITGDCNNRRSPALGAANRALARWLPAEYEDGLAVPFGWTQRKTRNGFRVPLAREVSN KIVGYLDEEGVLDQNRSLLFMQWGQIVDHDLDFAPETELGSSEHSKVQCEEYCIQGDNCFPIMFPKNDPKLKTQGKCMPF FRAGFVCPTPPYQSLARDQINSVTSFLDASLVYGSEPSLASRLRNLSSPLGLMAVNQEAWDHGLAYPPFNNMKPSPCEFI NTTARVPCFQAGDSRASEQILLATVHTLLLREHNRLARELKRLNPHWDGEKLYQEARKILGAFIQIITFRDYLPIVLGSE MQKWIPRYQGYNNSVDPRISNVFTFAFRFGHMEVPSTVSRLDENYQPRGPEAELPLHTLFFNTWRIIKDGGIDPLVRGLL AKKSKLMNQNKMVTSELRNKLFQPTHKIHGFDLAAINLQRCRDHGMPGYNSWRGFCGLSQPKTLKGLQAVLKNKILAKKL LDLYKTPDNIDIWIGGNAEPMVERGRVGPLLACLLGRQFQQIRDGDRFWWENPGVFTEKQRDSLQKVSFSRLICDNTHIT KVPLHAFQANNYPHDFVDCSAIDKLDLSPWASREN ; _entity_poly.pdbx_strand_id A,B _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 SER n 1 2 TRP n 1 3 GLU n 1 4 VAL n 1 5 GLY n 1 6 CYS n 1 7 GLY n 1 8 ALA n 1 9 PRO n 1 10 VAL n 1 11 PRO n 1 12 LEU n 1 13 VAL n 1 14 LYS n 1 15 CYS n 1 16 ASP n 1 17 GLU n 1 18 ASN n 1 19 SER n 1 20 PRO n 1 21 TYR n 1 22 ARG n 1 23 THR n 1 24 ILE n 1 25 THR n 1 26 GLY n 1 27 ASP n 1 28 CYS n 1 29 ASN n 1 30 ASN n 1 31 ARG n 1 32 ARG n 1 33 SER n 1 34 PRO n 1 35 ALA n 1 36 LEU n 1 37 GLY n 1 38 ALA n 1 39 ALA n 1 40 ASN n 1 41 ARG n 1 42 ALA n 1 43 LEU n 1 44 ALA n 1 45 ARG n 1 46 TRP n 1 47 LEU n 1 48 PRO n 1 49 ALA n 1 50 GLU n 1 51 TYR n 1 52 GLU n 1 53 ASP n 1 54 GLY n 1 55 LEU n 1 56 ALA n 1 57 VAL n 1 58 PRO n 1 59 PHE n 1 60 GLY n 1 61 TRP n 1 62 THR n 1 63 GLN n 1 64 ARG n 1 65 LYS n 1 66 THR n 1 67 ARG n 1 68 ASN n 1 69 GLY n 1 70 PHE n 1 71 ARG n 1 72 VAL n 1 73 PRO n 1 74 LEU n 1 75 ALA n 1 76 ARG n 1 77 GLU n 1 78 VAL n 1 79 SER n 1 80 ASN n 1 81 LYS n 1 82 ILE n 1 83 VAL n 1 84 GLY n 1 85 TYR n 1 86 LEU n 1 87 ASP n 1 88 GLU n 1 89 GLU n 1 90 GLY n 1 91 VAL n 1 92 LEU n 1 93 ASP n 1 94 GLN n 1 95 ASN n 1 96 ARG n 1 97 SER n 1 98 LEU n 1 99 LEU n 1 100 PHE n 1 101 MET n 1 102 GLN n 1 103 TRP n 1 104 GLY n 1 105 GLN n 1 106 ILE n 1 107 VAL n 1 108 ASP n 1 109 HIS n 1 110 ASP n 1 111 LEU n 1 112 ASP n 1 113 PHE n 1 114 ALA n 1 115 PRO n 1 116 GLU n 1 117 THR n 1 118 GLU n 1 119 LEU n 1 120 GLY n 1 121 SER n 1 122 SER n 1 123 GLU n 1 124 HIS n 1 125 SER n 1 126 LYS n 1 127 VAL n 1 128 GLN n 1 129 CYS n 1 130 GLU n 1 131 GLU n 1 132 TYR n 1 133 CYS n 1 134 ILE n 1 135 GLN n 1 136 GLY n 1 137 ASP n 1 138 ASN n 1 139 CYS n 1 140 PHE n 1 141 PRO n 1 142 ILE n 1 143 MET n 1 144 PHE n 1 145 PRO n 1 146 LYS n 1 147 ASN n 1 148 ASP n 1 149 PRO n 1 150 LYS n 1 151 LEU n 1 152 LYS n 1 153 THR n 1 154 GLN n 1 155 GLY n 1 156 LYS n 1 157 CYS n 1 158 MET n 1 159 PRO n 1 160 PHE n 1 161 PHE n 1 162 ARG n 1 163 ALA n 1 164 GLY n 1 165 PHE n 1 166 VAL n 1 167 CYS n 1 168 PRO n 1 169 THR n 1 170 PRO n 1 171 PRO n 1 172 TYR n 1 173 GLN n 1 174 SER n 1 175 LEU n 1 176 ALA n 1 177 ARG n 1 178 ASP n 1 179 GLN n 1 180 ILE n 1 181 ASN n 1 182 SER n 1 183 VAL n 1 184 THR n 1 185 SER n 1 186 PHE n 1 187 LEU n 1 188 ASP n 1 189 ALA n 1 190 SER n 1 191 LEU n 1 192 VAL n 1 193 TYR n 1 194 GLY n 1 195 SER n 1 196 GLU n 1 197 PRO n 1 198 SER n 1 199 LEU n 1 200 ALA n 1 201 SER n 1 202 ARG n 1 203 LEU n 1 204 ARG n 1 205 ASN n 1 206 LEU n 1 207 SER n 1 208 SER n 1 209 PRO n 1 210 LEU n 1 211 GLY n 1 212 LEU n 1 213 MET n 1 214 ALA n 1 215 VAL n 1 216 ASN n 1 217 GLN n 1 218 GLU n 1 219 ALA n 1 220 TRP n 1 221 ASP n 1 222 HIS n 1 223 GLY n 1 224 LEU n 1 225 ALA n 1 226 TYR n 1 227 PRO n 1 228 PRO n 1 229 PHE n 1 230 ASN n 1 231 ASN n 1 232 MET n 1 233 LYS n 1 234 PRO n 1 235 SER n 1 236 PRO n 1 237 CYS n 1 238 GLU n 1 239 PHE n 1 240 ILE n 1 241 ASN n 1 242 THR n 1 243 THR n 1 244 ALA n 1 245 ARG n 1 246 VAL n 1 247 PRO n 1 248 CYS n 1 249 PHE n 1 250 GLN n 1 251 ALA n 1 252 GLY n 1 253 ASP n 1 254 SER n 1 255 ARG n 1 256 ALA n 1 257 SER n 1 258 GLU n 1 259 GLN n 1 260 ILE n 1 261 LEU n 1 262 LEU n 1 263 ALA n 1 264 THR n 1 265 VAL n 1 266 HIS n 1 267 THR n 1 268 LEU n 1 269 LEU n 1 270 LEU n 1 271 ARG n 1 272 GLU n 1 273 HIS n 1 274 ASN n 1 275 ARG n 1 276 LEU n 1 277 ALA n 1 278 ARG n 1 279 GLU n 1 280 LEU n 1 281 LYS n 1 282 ARG n 1 283 LEU n 1 284 ASN n 1 285 PRO n 1 286 HIS n 1 287 TRP n 1 288 ASP n 1 289 GLY n 1 290 GLU n 1 291 LYS n 1 292 LEU n 1 293 TYR n 1 294 GLN n 1 295 GLU n 1 296 ALA n 1 297 ARG n 1 298 LYS n 1 299 ILE n 1 300 LEU n 1 301 GLY n 1 302 ALA n 1 303 PHE n 1 304 ILE n 1 305 GLN n 1 306 ILE n 1 307 ILE n 1 308 THR n 1 309 PHE n 1 310 ARG n 1 311 ASP n 1 312 TYR n 1 313 LEU n 1 314 PRO n 1 315 ILE n 1 316 VAL n 1 317 LEU n 1 318 GLY n 1 319 SER n 1 320 GLU n 1 321 MET n 1 322 GLN n 1 323 LYS n 1 324 TRP n 1 325 ILE n 1 326 PRO n 1 327 ARG n 1 328 TYR n 1 329 GLN n 1 330 GLY n 1 331 TYR n 1 332 ASN n 1 333 ASN n 1 334 SER n 1 335 VAL n 1 336 ASP n 1 337 PRO n 1 338 ARG n 1 339 ILE n 1 340 SER n 1 341 ASN n 1 342 VAL n 1 343 PHE n 1 344 THR n 1 345 PHE n 1 346 ALA n 1 347 PHE n 1 348 ARG n 1 349 PHE n 1 350 GLY n 1 351 HIS n 1 352 MET n 1 353 GLU n 1 354 VAL n 1 355 PRO n 1 356 SER n 1 357 THR n 1 358 VAL n 1 359 SER n 1 360 ARG n 1 361 LEU n 1 362 ASP n 1 363 GLU n 1 364 ASN n 1 365 TYR n 1 366 GLN n 1 367 PRO n 1 368 ARG n 1 369 GLY n 1 370 PRO n 1 371 GLU n 1 372 ALA n 1 373 GLU n 1 374 LEU n 1 375 PRO n 1 376 LEU n 1 377 HIS n 1 378 THR n 1 379 LEU n 1 380 PHE n 1 381 PHE n 1 382 ASN n 1 383 THR n 1 384 TRP n 1 385 ARG n 1 386 ILE n 1 387 ILE n 1 388 LYS n 1 389 ASP n 1 390 GLY n 1 391 GLY n 1 392 ILE n 1 393 ASP n 1 394 PRO n 1 395 LEU n 1 396 VAL n 1 397 ARG n 1 398 GLY n 1 399 LEU n 1 400 LEU n 1 401 ALA n 1 402 LYS n 1 403 LYS n 1 404 SER n 1 405 LYS n 1 406 LEU n 1 407 MET n 1 408 ASN n 1 409 GLN n 1 410 ASN n 1 411 LYS n 1 412 MET n 1 413 VAL n 1 414 THR n 1 415 SER n 1 416 GLU n 1 417 LEU n 1 418 ARG n 1 419 ASN n 1 420 LYS n 1 421 LEU n 1 422 PHE n 1 423 GLN n 1 424 PRO n 1 425 THR n 1 426 HIS n 1 427 LYS n 1 428 ILE n 1 429 HIS n 1 430 GLY n 1 431 PHE n 1 432 ASP n 1 433 LEU n 1 434 ALA n 1 435 ALA n 1 436 ILE n 1 437 ASN n 1 438 LEU n 1 439 GLN n 1 440 ARG n 1 441 CYS n 1 442 ARG n 1 443 ASP n 1 444 HIS n 1 445 GLY n 1 446 MET n 1 447 PRO n 1 448 GLY n 1 449 TYR n 1 450 ASN n 1 451 SER n 1 452 TRP n 1 453 ARG n 1 454 GLY n 1 455 PHE n 1 456 CYS n 1 457 GLY n 1 458 LEU n 1 459 SER n 1 460 GLN n 1 461 PRO n 1 462 LYS n 1 463 THR n 1 464 LEU n 1 465 LYS n 1 466 GLY n 1 467 LEU n 1 468 GLN n 1 469 ALA n 1 470 VAL n 1 471 LEU n 1 472 LYS n 1 473 ASN n 1 474 LYS n 1 475 ILE n 1 476 LEU n 1 477 ALA n 1 478 LYS n 1 479 LYS n 1 480 LEU n 1 481 LEU n 1 482 ASP n 1 483 LEU n 1 484 TYR n 1 485 LYS n 1 486 THR n 1 487 PRO n 1 488 ASP n 1 489 ASN n 1 490 ILE n 1 491 ASP n 1 492 ILE n 1 493 TRP n 1 494 ILE n 1 495 GLY n 1 496 GLY n 1 497 ASN n 1 498 ALA n 1 499 GLU n 1 500 PRO n 1 501 MET n 1 502 VAL n 1 503 GLU n 1 504 ARG n 1 505 GLY n 1 506 ARG n 1 507 VAL n 1 508 GLY n 1 509 PRO n 1 510 LEU n 1 511 LEU n 1 512 ALA n 1 513 CYS n 1 514 LEU n 1 515 LEU n 1 516 GLY n 1 517 ARG n 1 518 GLN n 1 519 PHE n 1 520 GLN n 1 521 GLN n 1 522 ILE n 1 523 ARG n 1 524 ASP n 1 525 GLY n 1 526 ASP n 1 527 ARG n 1 528 PHE n 1 529 TRP n 1 530 TRP n 1 531 GLU n 1 532 ASN n 1 533 PRO n 1 534 GLY n 1 535 VAL n 1 536 PHE n 1 537 THR n 1 538 GLU n 1 539 LYS n 1 540 GLN n 1 541 ARG n 1 542 ASP n 1 543 SER n 1 544 LEU n 1 545 GLN n 1 546 LYS n 1 547 VAL n 1 548 SER n 1 549 PHE n 1 550 SER n 1 551 ARG n 1 552 LEU n 1 553 ILE n 1 554 CYS n 1 555 ASP n 1 556 ASN n 1 557 THR n 1 558 HIS n 1 559 ILE n 1 560 THR n 1 561 LYS n 1 562 VAL n 1 563 PRO n 1 564 LEU n 1 565 HIS n 1 566 ALA n 1 567 PHE n 1 568 GLN n 1 569 ALA n 1 570 ASN n 1 571 ASN n 1 572 TYR n 1 573 PRO n 1 574 HIS n 1 575 ASP n 1 576 PHE n 1 577 VAL n 1 578 ASP n 1 579 CYS n 1 580 SER n 1 581 ALA n 1 582 ILE n 1 583 ASP n 1 584 LYS n 1 585 LEU n 1 586 ASP n 1 587 LEU n 1 588 SER n 1 589 PRO n 1 590 TRP n 1 591 ALA n 1 592 SER n 1 593 ARG n 1 594 GLU n 1 595 ASN n # _entity_src_nat.entity_id 1 _entity_src_nat.pdbx_src_id 1 _entity_src_nat.pdbx_alt_source_flag sample _entity_src_nat.pdbx_beg_seq_num ? _entity_src_nat.pdbx_end_seq_num ? _entity_src_nat.common_name sheep _entity_src_nat.pdbx_organism_scientific 'Ovis aries' _entity_src_nat.pdbx_ncbi_taxonomy_id 9940 _entity_src_nat.genus Ovis _entity_src_nat.species ? _entity_src_nat.strain ? _entity_src_nat.tissue ? _entity_src_nat.tissue_fraction ? _entity_src_nat.pdbx_secretion ? _entity_src_nat.pdbx_fragment ? _entity_src_nat.pdbx_variant ? _entity_src_nat.pdbx_cell_line ? _entity_src_nat.pdbx_atcc ? _entity_src_nat.pdbx_cellular_location ? _entity_src_nat.pdbx_organ ? _entity_src_nat.pdbx_organelle ? _entity_src_nat.pdbx_cell ? _entity_src_nat.pdbx_plasmid_name ? _entity_src_nat.pdbx_plasmid_details ? _entity_src_nat.details ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code Q9MZY2_SHEEP _struct_ref.pdbx_db_accession Q9MZY2 _struct_ref.entity_id 1 _struct_ref.pdbx_align_begin 118 _struct_ref.pdbx_db_isoform ? _struct_ref.pdbx_seq_one_letter_code ? # loop_ _struct_ref_seq.align_id _struct_ref_seq.ref_id _struct_ref_seq.pdbx_PDB_id_code _struct_ref_seq.pdbx_strand_id _struct_ref_seq.seq_align_beg _struct_ref_seq.pdbx_seq_align_beg_ins_code _struct_ref_seq.seq_align_end _struct_ref_seq.pdbx_seq_align_end_ins_code _struct_ref_seq.pdbx_db_accession _struct_ref_seq.db_align_beg _struct_ref_seq.pdbx_db_align_beg_ins_code _struct_ref_seq.db_align_end _struct_ref_seq.pdbx_db_align_end_ins_code _struct_ref_seq.pdbx_auth_seq_align_beg _struct_ref_seq.pdbx_auth_seq_align_end 1 1 2IKC A 1 ? 595 ? Q9MZY2 118 ? 712 ? 1 595 2 1 2IKC B 1 ? 595 ? Q9MZY2 118 ? 712 ? 1 595 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CA non-polymer . 'CALCIUM ION' ? 'Ca 2' 40.078 CO3 non-polymer . 'CARBONATE ION' ? 'C O3 -2' 60.009 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 FMT non-polymer . 'FORMIC ACID' ? 'C H2 O2' 46.025 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HEM non-polymer . 'PROTOPORPHYRIN IX CONTAINING FE' HEME 'C34 H32 Fe N4 O4' 616.487 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MAN D-saccharide . ALPHA-D-MANNOSE ? 'C6 H12 O6' 180.156 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 # _exptl.entry_id 2IKC _exptl.method 'X-RAY DIFFRACTION' _exptl.crystals_number ? # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.57 _exptl_crystal.density_percent_sol 52.13 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _diffrn.id 1 _diffrn.ambient_temp 295 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector 'IMAGE PLATE' _diffrn_detector.type 'MAR scanner 345 mm plate' _diffrn_detector.pdbx_collection_date 2006-09-20 _diffrn_detector.details Mirror # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.monochromator graphite _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 1.54132 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source 'ROTATING ANODE' _diffrn_source.type 'RIGAKU RU300' _diffrn_source.pdbx_synchrotron_site ? _diffrn_source.pdbx_synchrotron_beamline ? _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_wavelength_list 1.54132 # _reflns.entry_id 2IKC _reflns.observed_criterion_sigma_I 0 _reflns.observed_criterion_sigma_F 0 _reflns.d_resolution_low 19.97 _reflns.d_resolution_high 3.25 _reflns.number_obs 20388 _reflns.number_all 20423 _reflns.percent_possible_obs 96.5 _reflns.pdbx_Rmerge_I_obs ? _reflns.pdbx_Rsym_value ? _reflns.pdbx_netI_over_sigmaI ? _reflns.B_iso_Wilson_estimate 37.9 _reflns.pdbx_redundancy ? _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_chi_squared ? _reflns.pdbx_scaling_rejects ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_high 3.25 _reflns_shell.d_res_low 3.31 _reflns_shell.percent_possible_all 96.5 _reflns_shell.Rmerge_I_obs ? _reflns_shell.pdbx_Rsym_value ? _reflns_shell.meanI_over_sigI_obs ? _reflns_shell.pdbx_redundancy ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_unique_all ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.number_unique_obs ? _reflns_shell.pdbx_chi_squared ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.entry_id 2IKC _refine.ls_number_reflns_obs 20328 _refine.ls_number_reflns_all 20423 _refine.pdbx_ls_sigma_I 0 _refine.pdbx_ls_sigma_F 0.0 _refine.pdbx_data_cutoff_high_absF 30133.34 _refine.pdbx_data_cutoff_low_absF 0.000000 _refine.pdbx_data_cutoff_high_rms_absF ? _refine.ls_d_res_low 19.97 _refine.ls_d_res_high 3.25 _refine.ls_percent_reflns_obs 96.4 _refine.ls_R_factor_obs 0.187 _refine.ls_R_factor_all ? _refine.ls_R_factor_R_work 0.187 _refine.ls_R_factor_R_free 0.23 _refine.ls_R_factor_R_free_error 0.009 _refine.ls_R_factor_R_free_error_details ? _refine.ls_percent_reflns_R_free 2.9 _refine.ls_number_reflns_R_free 600 _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.occupancy_min ? _refine.occupancy_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.B_iso_mean 11.0 _refine.aniso_B[1][1] 7.33 _refine.aniso_B[2][2] -4.54 _refine.aniso_B[3][3] -2.79 _refine.aniso_B[1][2] 9.48 _refine.aniso_B[1][3] 2.13 _refine.aniso_B[2][3] -1.60 _refine.solvent_model_details 'FLAT MODEL' _refine.solvent_model_param_ksol 0.366155 _refine.solvent_model_param_bsol 72.4964 _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.details ? _refine.pdbx_starting_model 2GJ1 _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_R_Free_selection_details RANDOM _refine.pdbx_overall_ESU_R ? _refine.pdbx_overall_ESU_R_Free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.ls_redundancy_reflns_obs ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 2IKC _refine_analyze.Luzzati_coordinate_error_obs 0.29 _refine_analyze.Luzzati_sigma_a_obs 0.37 _refine_analyze.Luzzati_d_res_low_obs 5.00 _refine_analyze.Luzzati_coordinate_error_free 0.37 _refine_analyze.Luzzati_sigma_a_free 0.54 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 9528 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 332 _refine_hist.number_atoms_solvent 148 _refine_hist.number_atoms_total 10008 _refine_hist.d_res_high 3.25 _refine_hist.d_res_low 19.97 # loop_ _refine_ls_restr.type _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.number _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d 0.013 ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_bond_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg 2.2 ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_angle_deg_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d 24.3 ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d 1.26 ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_na ? ? ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d_prot ? ? ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it 1.28 1.50 ? ? 'X-RAY DIFFRACTION' ? c_mcangle_it 2.17 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scbond_it 1.80 2.00 ? ? 'X-RAY DIFFRACTION' ? c_scangle_it 3.00 2.50 ? ? 'X-RAY DIFFRACTION' ? # _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.d_res_high 3.25 _refine_ls_shell.d_res_low 3.45 _refine_ls_shell.number_reflns_R_work 3293 _refine_ls_shell.R_factor_R_work 0.237 _refine_ls_shell.percent_reflns_obs 96.2 _refine_ls_shell.R_factor_R_free 0.308 _refine_ls_shell.R_factor_R_free_error 0.032 _refine_ls_shell.percent_reflns_R_free 2.7 _refine_ls_shell.number_reflns_R_free 91 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.R_factor_all ? _refine_ls_shell.number_reflns_obs ? _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 protein_rep.param protein.top 'X-RAY DIFFRACTION' 2 ion.param ion.top 'X-RAY DIFFRACTION' 3 water_rep.param water.top 'X-RAY DIFFRACTION' 4 all.param all.top 'X-RAY DIFFRACTION' 5 carbohydrate.param carbohydrate.top 'X-RAY DIFFRACTION' # _struct.entry_id 2IKC _struct.title 'Crystal structure of sheep lactoperoxidase at 3.25 A resolution reveals the binding sites for formate' _struct.pdbx_descriptor 'Milk lactoperoxidase (E.C.1.11.1.7)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2IKC _struct_keywords.pdbx_keywords OXIDOREDUCTASE _struct_keywords.text 'Peroxidase, Formate, Heme, OXIDOREDUCTASE' # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 1 ? C N N 2 ? D N N 2 ? E N N 2 ? F N N 2 ? G N N 2 ? H N N 2 ? I N N 3 ? J N N 2 ? K N N 4 ? L N N 5 ? M N N 6 ? N N N 7 ? O N N 7 ? P N N 7 ? Q N N 2 ? R N N 2 ? S N N 2 ? T N N 2 ? U N N 2 ? V N N 2 ? W N N 3 ? X N N 2 ? Y N N 4 ? Z N N 5 ? AA N N 6 ? BA N N 7 ? CA N N 7 ? DA N N 7 ? EA N N 8 ? FA N N 8 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 LEU A 74 ? ILE A 82 ? LEU A 74 ILE A 82 1 ? 9 HELX_P HELX_P2 2 LEU A 98 ? ASP A 112 ? LEU A 98 ASP A 112 1 ? 15 HELX_P HELX_P3 3 ASP A 148 ? GLN A 154 ? ASP A 148 GLN A 154 1 ? 7 HELX_P HELX_P4 4 ALA A 189 ? GLY A 194 ? ALA A 189 GLY A 194 1 ? 6 HELX_P HELX_P5 5 GLU A 196 ? LEU A 203 ? GLU A 196 LEU A 203 1 ? 8 HELX_P HELX_P6 6 SER A 235 ? ASN A 241 ? SER A 235 ASN A 241 1 ? 7 HELX_P HELX_P7 7 ASP A 253 ? GLU A 258 ? ASP A 253 GLU A 258 5 ? 6 HELX_P HELX_P8 8 GLN A 259 ? ASN A 284 ? GLN A 259 ASN A 284 1 ? 26 HELX_P HELX_P9 9 ASP A 288 ? ASP A 311 ? ASP A 288 ASP A 311 1 ? 24 HELX_P HELX_P10 10 LEU A 313 ? GLY A 318 ? LEU A 313 GLY A 318 1 ? 6 HELX_P HELX_P11 11 GLU A 320 ? ILE A 325 ? GLU A 320 ILE A 325 1 ? 6 HELX_P HELX_P12 12 VAL A 342 ? PHE A 347 ? VAL A 342 PHE A 347 1 ? 6 HELX_P HELX_P13 13 ARG A 348 ? GLU A 353 ? ARG A 348 GLU A 353 5 ? 6 HELX_P HELX_P14 14 HIS A 377 ? PHE A 380 ? HIS A 377 PHE A 380 5 ? 4 HELX_P HELX_P15 15 THR A 383 ? LYS A 388 ? THR A 383 LYS A 388 1 ? 6 HELX_P HELX_P16 16 ILE A 392 ? LYS A 402 ? ILE A 392 LYS A 402 1 ? 11 HELX_P HELX_P17 17 THR A 414 ? ASN A 419 ? THR A 414 ASN A 419 1 ? 6 HELX_P HELX_P18 18 ASP A 432 ? HIS A 444 ? ASP A 432 HIS A 444 1 ? 13 HELX_P HELX_P19 19 TYR A 449 ? CYS A 456 ? TYR A 449 CYS A 456 1 ? 8 HELX_P HELX_P20 20 THR A 463 ? LYS A 472 ? THR A 463 LYS A 472 1 ? 10 HELX_P HELX_P21 21 ASN A 473 ? LYS A 485 ? ASN A 473 LYS A 485 1 ? 13 HELX_P HELX_P22 22 THR A 486 ? ILE A 490 ? THR A 486 ILE A 490 5 ? 5 HELX_P HELX_P23 23 ASP A 491 ? GLU A 499 ? ASP A 491 GLU A 499 1 ? 9 HELX_P HELX_P24 24 GLY A 508 ? GLY A 525 ? GLY A 508 GLY A 525 1 ? 18 HELX_P HELX_P25 25 THR A 537 ? GLN A 545 ? THR A 537 GLN A 545 1 ? 9 HELX_P HELX_P26 26 SER A 548 ? ASN A 556 ? SER A 548 ASN A 556 1 ? 9 HELX_P HELX_P27 27 SER A 580 ? ILE A 582 ? SER A 580 ILE A 582 5 ? 3 HELX_P HELX_P28 28 LEU A 587 ? ALA A 591 ? LEU A 587 ALA A 591 5 ? 5 HELX_P HELX_P29 29 LEU B 74 ? VAL B 83 ? LEU B 74 VAL B 83 1 ? 10 HELX_P HELX_P30 30 LEU B 98 ? ASP B 112 ? LEU B 98 ASP B 112 1 ? 15 HELX_P HELX_P31 31 HIS B 124 ? GLU B 131 ? HIS B 124 GLU B 131 1 ? 8 HELX_P HELX_P32 32 PRO B 149 ? GLN B 154 ? PRO B 149 GLN B 154 1 ? 6 HELX_P HELX_P33 33 ALA B 189 ? GLY B 194 ? ALA B 189 GLY B 194 1 ? 6 HELX_P HELX_P34 34 GLU B 196 ? LEU B 203 ? GLU B 196 LEU B 203 1 ? 8 HELX_P HELX_P35 35 SER B 235 ? ILE B 240 ? SER B 235 ILE B 240 1 ? 6 HELX_P HELX_P36 36 GLN B 259 ? ASN B 284 ? GLN B 259 ASN B 284 1 ? 26 HELX_P HELX_P37 37 ASP B 288 ? ASP B 311 ? ASP B 288 ASP B 311 1 ? 24 HELX_P HELX_P38 38 LEU B 313 ? GLY B 318 ? LEU B 313 GLY B 318 1 ? 6 HELX_P HELX_P39 39 GLU B 320 ? ILE B 325 ? GLU B 320 ILE B 325 1 ? 6 HELX_P HELX_P40 40 VAL B 342 ? PHE B 347 ? VAL B 342 PHE B 347 1 ? 6 HELX_P HELX_P41 41 ARG B 348 ? VAL B 354 ? ARG B 348 VAL B 354 5 ? 7 HELX_P HELX_P42 42 HIS B 377 ? PHE B 380 ? HIS B 377 PHE B 380 5 ? 4 HELX_P HELX_P43 43 THR B 383 ? LYS B 388 ? THR B 383 LYS B 388 1 ? 6 HELX_P HELX_P44 44 ILE B 392 ? LYS B 402 ? ILE B 392 LYS B 402 1 ? 11 HELX_P HELX_P45 45 THR B 414 ? ASN B 419 ? THR B 414 ASN B 419 1 ? 6 HELX_P HELX_P46 46 ASP B 432 ? GLY B 445 ? ASP B 432 GLY B 445 1 ? 14 HELX_P HELX_P47 47 GLY B 448 ? GLY B 457 ? GLY B 448 GLY B 457 1 ? 10 HELX_P HELX_P48 48 THR B 463 ? LYS B 472 ? THR B 463 LYS B 472 1 ? 10 HELX_P HELX_P49 49 ASN B 473 ? LYS B 485 ? ASN B 473 LYS B 485 1 ? 13 HELX_P HELX_P50 50 THR B 486 ? ILE B 490 ? THR B 486 ILE B 490 5 ? 5 HELX_P HELX_P51 51 ASP B 491 ? GLU B 499 ? ASP B 491 GLU B 499 1 ? 9 HELX_P HELX_P52 52 GLY B 508 ? GLY B 525 ? GLY B 508 GLY B 525 1 ? 18 HELX_P HELX_P53 53 THR B 537 ? GLN B 545 ? THR B 537 GLN B 545 1 ? 9 HELX_P HELX_P54 54 SER B 548 ? THR B 557 ? SER B 548 THR B 557 1 ? 10 HELX_P HELX_P55 55 SER B 580 ? ILE B 582 ? SER B 580 ILE B 582 5 ? 3 HELX_P HELX_P56 56 LEU B 587 ? ALA B 591 ? LEU B 587 ALA B 591 5 ? 5 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 6 SG ? ? ? 1_555 A CYS 167 SG ? ? A CYS 6 A CYS 167 1_555 ? ? ? ? ? ? ? 2.226 ? disulf2 disulf ? ? A CYS 15 SG ? ? ? 1_555 A CYS 28 SG ? ? A CYS 15 A CYS 28 1_555 ? ? ? ? ? ? ? 2.245 ? disulf3 disulf ? ? A CYS 129 SG ? ? ? 1_555 A CYS 139 SG ? ? A CYS 129 A CYS 139 1_555 ? ? ? ? ? ? ? 1.874 ? disulf4 disulf ? ? A CYS 133 SG ? ? ? 1_555 A CYS 157 SG ? ? A CYS 133 A CYS 157 1_555 ? ? ? ? ? ? ? 1.983 ? disulf5 disulf ? ? A CYS 237 SG ? ? ? 1_555 A CYS 248 SG ? ? A CYS 237 A CYS 248 1_555 ? ? ? ? ? ? ? 2.025 ? disulf6 disulf ? ? A CYS 456 SG ? ? ? 1_555 A CYS 513 SG ? ? A CYS 456 A CYS 513 1_555 ? ? ? ? ? ? ? 2.031 ? disulf7 disulf ? ? A CYS 554 SG ? ? ? 1_555 A CYS 579 SG ? ? A CYS 554 A CYS 579 1_555 ? ? ? ? ? ? ? 2.025 ? disulf8 disulf ? ? B CYS 6 SG ? ? ? 1_555 B CYS 167 SG ? ? B CYS 6 B CYS 167 1_555 ? ? ? ? ? ? ? 2.089 ? disulf9 disulf ? ? B CYS 15 SG ? ? ? 1_555 B CYS 28 SG ? ? B CYS 15 B CYS 28 1_555 ? ? ? ? ? ? ? 2.048 ? disulf10 disulf ? ? B CYS 129 SG ? ? ? 1_555 B CYS 139 SG ? ? B CYS 129 B CYS 139 1_555 ? ? ? ? ? ? ? 2.034 ? disulf11 disulf ? ? B CYS 133 SG ? ? ? 1_555 B CYS 157 SG ? ? B CYS 133 B CYS 157 1_555 ? ? ? ? ? ? ? 2.028 ? disulf12 disulf ? ? B CYS 237 SG ? ? ? 1_555 B CYS 248 SG ? ? B CYS 237 B CYS 248 1_555 ? ? ? ? ? ? ? 2.020 ? disulf13 disulf ? ? B CYS 456 SG ? ? ? 1_555 B CYS 513 SG ? ? B CYS 456 B CYS 513 1_555 ? ? ? ? ? ? ? 2.031 ? disulf14 disulf ? ? B CYS 554 SG ? ? ? 1_555 B CYS 579 SG ? ? B CYS 554 B CYS 579 1_555 ? ? ? ? ? ? ? 2.012 ? metalc1 metalc ? ? M HEM . FE ? ? ? 1_555 A HIS 351 NE2 ? ? A HEM 605 A HIS 351 1_555 ? ? ? ? ? ? ? 2.174 ? covale1 covale ? ? M HEM . CMD ? ? ? 1_555 A ASP 108 OD2 ? ? A HEM 605 A ASP 108 1_555 ? ? ? ? ? ? ? 1.806 ? covale2 covale ? ? M HEM . CMB ? ? ? 1_555 A GLU 258 OE2 ? ? A HEM 605 A GLU 258 1_555 ? ? ? ? ? ? ? 1.511 ? metalc2 metalc ? ? AA HEM . FE ? ? ? 1_555 B HIS 351 NE2 ? ? B HEM 605 B HIS 351 1_555 ? ? ? ? ? ? ? 2.350 ? covale3 covale ? ? AA HEM . CMD ? ? ? 1_555 B ASP 108 OD2 ? ? B HEM 605 B ASP 108 1_555 ? ? ? ? ? ? ? 1.516 ? covale4 covale ? ? AA HEM . CMB ? ? ? 1_555 B GLU 258 OE2 ? ? B HEM 605 B GLU 258 1_555 ? ? ? ? ? ? ? 1.574 ? covale5 covale ? ? A ASN 95 ND2 ? ? ? 1_555 C NAG . C1 ? ? A ASN 95 A NAG 596 1_555 ? ? ? ? ? ? ? 1.390 ? covale6 covale ? ? A ASN 205 ND2 ? ? ? 1_555 E NAG . C1 ? ? A ASN 205 A NAG 598 1_555 ? ? ? ? ? ? ? 1.452 ? covale7 covale ? ? A ASN 241 ND2 ? ? ? 1_555 G NAG . C1 ? ? A ASN 241 A NAG 600 1_555 ? ? ? ? ? ? ? 1.448 ? covale8 covale ? ? A ASN 332 ND2 ? ? ? 1_555 J NAG . C1 ? ? A ASN 332 A NAG 603 1_555 ? ? ? ? ? ? ? 1.447 ? covale9 covale ? ? B ASN 95 ND2 ? ? ? 1_555 Q NAG . C1 ? ? B ASN 95 B NAG 596 1_555 ? ? ? ? ? ? ? 1.457 ? covale10 covale ? ? B ASN 205 ND2 ? ? ? 1_555 S NAG . C1 ? ? B ASN 205 B NAG 598 1_555 ? ? ? ? ? ? ? 1.513 ? covale11 covale ? ? B ASN 241 ND2 ? ? ? 1_555 U NAG . C1 ? ? B ASN 241 B NAG 600 1_555 ? ? ? ? ? ? ? 1.439 ? covale12 covale ? ? B ASN 332 ND2 ? ? ? 1_555 X NAG . C1 ? ? B ASN 332 B NAG 603 1_555 ? ? ? ? ? ? ? 1.436 ? covale13 covale ? ? C NAG . O4 ? ? ? 1_555 D NAG . C1 ? ? A NAG 596 A NAG 597 1_555 ? ? ? ? ? ? ? 1.396 ? covale14 covale ? ? E NAG . O4 ? ? ? 1_555 F NAG . C1 ? ? A NAG 598 A NAG 599 1_555 ? ? ? ? ? ? ? 1.397 ? covale15 covale ? ? G NAG . O4 ? ? ? 1_555 H NAG . C1 ? ? A NAG 600 A NAG 601 1_555 ? ? ? ? ? ? ? 1.386 ? covale16 covale ? ? H NAG . O4 ? ? ? 1_555 I MAN . C1 ? ? A NAG 601 A MAN 602 1_555 ? ? ? ? ? ? ? 1.403 ? covale17 covale ? ? Q NAG . O4 ? ? ? 1_555 R NAG . C1 ? ? B NAG 596 B NAG 597 1_555 ? ? ? ? ? ? ? 1.389 ? covale18 covale ? ? S NAG . O4 ? ? ? 1_555 T NAG . C1 ? ? B NAG 598 B NAG 599 1_555 ? ? ? ? ? ? ? 1.398 ? covale19 covale ? ? U NAG . O4 ? ? ? 1_555 V NAG . C1 ? ? B NAG 600 B NAG 601 1_555 ? ? ? ? ? ? ? 1.395 ? covale20 covale ? ? V NAG . O4 ? ? ? 1_555 W MAN . C1 ? ? B NAG 601 B MAN 602 1_555 ? ? ? ? ? ? ? 1.465 ? metalc3 metalc ? ? A ASP 110 O ? ? ? 1_555 K CA . CA ? ? A ASP 110 A CA 1001 1_555 ? ? ? ? ? ? ? 2.555 ? metalc4 metalc ? ? A ASP 110 OD1 ? ? ? 1_555 K CA . CA ? ? A ASP 110 A CA 1001 1_555 ? ? ? ? ? ? ? 2.446 ? metalc5 metalc ? ? A THR 184 O ? ? ? 1_555 K CA . CA ? ? A THR 184 A CA 1001 1_555 ? ? ? ? ? ? ? 2.588 ? metalc6 metalc ? ? A THR 184 OG1 ? ? ? 1_555 K CA . CA ? ? A THR 184 A CA 1001 1_555 ? ? ? ? ? ? ? 2.487 ? metalc7 metalc ? ? A PHE 186 O ? ? ? 1_555 K CA . CA ? ? A PHE 186 A CA 1001 1_555 ? ? ? ? ? ? ? 2.561 ? metalc8 metalc ? ? A ASP 188 OD1 ? ? ? 1_555 K CA . CA ? ? A ASP 188 A CA 1001 1_555 ? ? ? ? ? ? ? 2.348 ? metalc9 metalc ? ? A SER 190 OG ? ? ? 1_555 K CA . CA ? ? A SER 190 A CA 1001 1_555 ? ? ? ? ? ? ? 2.830 ? metalc10 metalc ? ? B ASP 110 O ? ? ? 1_555 Y CA . CA ? ? B ASP 110 B CA 1002 1_555 ? ? ? ? ? ? ? 2.576 ? metalc11 metalc ? ? B ASP 110 OD1 ? ? ? 1_555 Y CA . CA ? ? B ASP 110 B CA 1002 1_555 ? ? ? ? ? ? ? 2.313 ? metalc12 metalc ? ? B THR 184 O ? ? ? 1_555 Y CA . CA ? ? B THR 184 B CA 1002 1_555 ? ? ? ? ? ? ? 2.451 ? metalc13 metalc ? ? B THR 184 OG1 ? ? ? 1_555 Y CA . CA ? ? B THR 184 B CA 1002 1_555 ? ? ? ? ? ? ? 2.516 ? metalc14 metalc ? ? B PHE 186 O ? ? ? 1_555 Y CA . CA ? ? B PHE 186 B CA 1002 1_555 ? ? ? ? ? ? ? 2.499 ? metalc15 metalc ? ? B ASP 188 OD1 ? ? ? 1_555 Y CA . CA ? ? B ASP 188 B CA 1002 1_555 ? ? ? ? ? ? ? 2.488 ? metalc16 metalc ? ? B SER 190 OG ? ? ? 1_555 Y CA . CA ? ? B SER 190 B CA 1002 1_555 ? ? ? ? ? ? ? 2.706 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? metalc ? ? covale ? ? # _struct_mon_prot_cis.pdbx_id 1 _struct_mon_prot_cis.label_comp_id TYR _struct_mon_prot_cis.label_seq_id 572 _struct_mon_prot_cis.label_asym_id A _struct_mon_prot_cis.label_alt_id . _struct_mon_prot_cis.pdbx_PDB_ins_code ? _struct_mon_prot_cis.auth_comp_id TYR _struct_mon_prot_cis.auth_seq_id 572 _struct_mon_prot_cis.auth_asym_id A _struct_mon_prot_cis.pdbx_label_comp_id_2 PRO _struct_mon_prot_cis.pdbx_label_seq_id_2 573 _struct_mon_prot_cis.pdbx_label_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_ins_code_2 ? _struct_mon_prot_cis.pdbx_auth_comp_id_2 PRO _struct_mon_prot_cis.pdbx_auth_seq_id_2 573 _struct_mon_prot_cis.pdbx_auth_asym_id_2 A _struct_mon_prot_cis.pdbx_PDB_model_num 1 _struct_mon_prot_cis.pdbx_omega_angle 0.20 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 2 ? B ? 2 ? C ? 2 ? D ? 2 ? E ? 2 ? F ? 2 ? G ? 2 ? H ? 2 ? I ? 2 ? J ? 2 ? K ? 2 ? L ? 2 ? M ? 2 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? anti-parallel B 1 2 ? anti-parallel C 1 2 ? anti-parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel F 1 2 ? anti-parallel G 1 2 ? anti-parallel H 1 2 ? anti-parallel I 1 2 ? anti-parallel J 1 2 ? anti-parallel K 1 2 ? anti-parallel L 1 2 ? anti-parallel M 1 2 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 LEU A 92 ? SER A 97 ? LEU A 92 SER A 97 A 2 LYS A 403 ? LYS A 405 ? LYS A 403 LYS A 405 B 1 ILE A 142 ? MET A 143 ? ILE A 142 MET A 143 B 2 CYS A 157 ? MET A 158 ? CYS A 157 MET A 158 C 1 ARG A 204 ? ASN A 205 ? ARG A 204 ASN A 205 C 2 LEU A 212 ? MET A 213 ? LEU A 212 MET A 213 D 1 THR A 357 ? VAL A 358 ? THR A 357 VAL A 358 D 2 LEU A 374 ? PRO A 375 ? LEU A 374 PRO A 375 E 1 LEU A 361 ? ASP A 362 ? LEU A 361 ASP A 362 E 2 GLN A 366 ? PRO A 367 ? GLN A 366 PRO A 367 F 1 LYS A 561 ? VAL A 562 ? LYS A 561 VAL A 562 F 2 VAL A 577 ? ASP A 578 ? VAL A 577 ASP A 578 G 1 ARG B 41 ? ALA B 42 ? ARG B 41 ALA B 42 G 2 ILE B 180 ? ASN B 181 ? ILE B 180 ASN B 181 H 1 LEU B 92 ? SER B 97 ? LEU B 92 SER B 97 H 2 LYS B 403 ? LYS B 405 ? LYS B 403 LYS B 405 I 1 ILE B 142 ? MET B 143 ? ILE B 142 MET B 143 I 2 CYS B 157 ? MET B 158 ? CYS B 157 MET B 158 J 1 ARG B 204 ? ASN B 205 ? ARG B 204 ASN B 205 J 2 LEU B 212 ? MET B 213 ? LEU B 212 MET B 213 K 1 THR B 357 ? SER B 359 ? THR B 357 SER B 359 K 2 GLU B 373 ? PRO B 375 ? GLU B 373 PRO B 375 L 1 LEU B 361 ? ASP B 362 ? LEU B 361 ASP B 362 L 2 GLN B 366 ? PRO B 367 ? GLN B 366 PRO B 367 M 1 LYS B 561 ? PRO B 563 ? LYS B 561 PRO B 563 M 2 PHE B 576 ? ASP B 578 ? PHE B 576 ASP B 578 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N ARG A 96 ? N ARG A 96 O SER A 404 ? O SER A 404 B 1 2 N ILE A 142 ? N ILE A 142 O MET A 158 ? O MET A 158 C 1 2 N ASN A 205 ? N ASN A 205 O LEU A 212 ? O LEU A 212 D 1 2 N VAL A 358 ? N VAL A 358 O LEU A 374 ? O LEU A 374 E 1 2 N ASP A 362 ? N ASP A 362 O GLN A 366 ? O GLN A 366 F 1 2 N VAL A 562 ? N VAL A 562 O VAL A 577 ? O VAL A 577 G 1 2 N ARG B 41 ? N ARG B 41 O ASN B 181 ? O ASN B 181 H 1 2 N ARG B 96 ? N ARG B 96 O SER B 404 ? O SER B 404 I 1 2 N ILE B 142 ? N ILE B 142 O MET B 158 ? O MET B 158 J 1 2 N ASN B 205 ? N ASN B 205 O LEU B 212 ? O LEU B 212 K 1 2 N VAL B 358 ? N VAL B 358 O LEU B 374 ? O LEU B 374 L 1 2 N ASP B 362 ? N ASP B 362 O GLN B 366 ? O GLN B 366 M 1 2 N VAL B 562 ? N VAL B 562 O VAL B 577 ? O VAL B 577 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG A 596' AC2 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG A 597' AC3 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NAG A 598' AC4 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 599' AC5 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG A 600' AC6 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 601' AC7 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE MAN A 602' AC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE NAG A 603' AC9 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE NAG B 596' BC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE NAG B 597' BC2 Software ? ? ? ? 6 'BINDING SITE FOR RESIDUE NAG B 598' BC3 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG B 599' BC4 Software ? ? ? ? 7 'BINDING SITE FOR RESIDUE NAG B 600' BC5 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG B 601' BC6 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE MAN B 602' BC7 Software ? ? ? ? 2 'BINDING SITE FOR RESIDUE NAG B 603' BC8 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE CA A 1001' BC9 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE CA B 1002' CC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE CO3 A 2001' CC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE CO3 B 2002' CC3 Software ? ? ? ? 17 'BINDING SITE FOR RESIDUE HEM A 605' CC4 Software ? ? ? ? 21 'BINDING SITE FOR RESIDUE HEM B 605' CC5 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FMT A 3001' CC6 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE FMT A 3002' CC7 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FMT A 3003' CC8 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE FMT B 3004' CC9 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE FMT B 3005' DC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE FMT B 3006' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 5 ASN A 95 ? ASN A 95 . ? 1_555 ? 2 AC1 5 ARG A 96 ? ARG A 96 . ? 1_555 ? 3 AC1 5 ARG A 504 ? ARG A 504 . ? 1_555 ? 4 AC1 5 NAG D . ? NAG A 597 . ? 1_555 ? 5 AC1 5 CO3 L . ? CO3 A 2001 . ? 1_555 ? 6 AC2 2 ARG A 504 ? ARG A 504 . ? 1_555 ? 7 AC2 2 NAG C . ? NAG A 596 . ? 1_555 ? 8 AC3 7 ASN A 205 ? ASN A 205 . ? 1_555 ? 9 AC3 7 SER A 208 ? SER A 208 . ? 1_555 ? 10 AC3 7 LEU A 210 ? LEU A 210 . ? 1_555 ? 11 AC3 7 VAL A 215 ? VAL A 215 . ? 1_555 ? 12 AC3 7 GLN A 217 ? GLN A 217 . ? 1_555 ? 13 AC3 7 NAG F . ? NAG A 599 . ? 1_555 ? 14 AC3 7 HOH EA . ? HOH A 3023 . ? 1_555 ? 15 AC4 1 NAG E . ? NAG A 598 . ? 1_555 ? 16 AC5 6 ASN A 241 ? ASN A 241 . ? 1_555 ? 17 AC5 6 ALA A 244 ? ALA A 244 . ? 1_555 ? 18 AC5 6 TRP A 384 ? TRP A 384 . ? 1_555 ? 19 AC5 6 NAG H . ? NAG A 601 . ? 1_555 ? 20 AC5 6 PHE B 70 ? PHE B 70 . ? 1_545 ? 21 AC5 6 LYS B 485 ? LYS B 485 . ? 1_545 ? 22 AC6 3 NAG G . ? NAG A 600 . ? 1_555 ? 23 AC6 3 MAN I . ? MAN A 602 . ? 1_555 ? 24 AC6 3 LYS B 485 ? LYS B 485 . ? 1_545 ? 25 AC7 1 NAG H . ? NAG A 601 . ? 1_555 ? 26 AC8 3 ASN A 332 ? ASN A 332 . ? 1_555 ? 27 AC8 3 VAL A 335 ? VAL A 335 . ? 1_555 ? 28 AC8 3 HOH EA . ? HOH A 3054 . ? 1_555 ? 29 AC9 5 ASN B 95 ? ASN B 95 . ? 1_555 ? 30 AC9 5 ARG B 504 ? ARG B 504 . ? 1_555 ? 31 AC9 5 GLN B 568 ? GLN B 568 . ? 1_555 ? 32 AC9 5 NAG R . ? NAG B 597 . ? 1_555 ? 33 AC9 5 CO3 Z . ? CO3 B 2002 . ? 1_555 ? 34 BC1 4 ARG B 504 ? ARG B 504 . ? 1_555 ? 35 BC1 4 HIS B 565 ? HIS B 565 . ? 1_555 ? 36 BC1 4 GLN B 568 ? GLN B 568 . ? 1_555 ? 37 BC1 4 NAG Q . ? NAG B 596 . ? 1_555 ? 38 BC2 6 LEU A 206 ? LEU A 206 . ? 1_556 ? 39 BC2 6 ASN B 205 ? ASN B 205 . ? 1_555 ? 40 BC2 6 VAL B 215 ? VAL B 215 . ? 1_555 ? 41 BC2 6 GLN B 217 ? GLN B 217 . ? 1_555 ? 42 BC2 6 NAG T . ? NAG B 599 . ? 1_555 ? 43 BC2 6 HOH FA . ? HOH B 3014 . ? 1_555 ? 44 BC3 1 NAG S . ? NAG B 598 . ? 1_555 ? 45 BC4 7 PHE A 70 ? PHE A 70 . ? 1_655 ? 46 BC4 7 LYS A 485 ? LYS A 485 . ? 1_655 ? 47 BC4 7 ASN B 241 ? ASN B 241 . ? 1_555 ? 48 BC4 7 ALA B 244 ? ALA B 244 . ? 1_555 ? 49 BC4 7 TRP B 384 ? TRP B 384 . ? 1_555 ? 50 BC4 7 LYS B 388 ? LYS B 388 . ? 1_555 ? 51 BC4 7 NAG V . ? NAG B 601 . ? 1_555 ? 52 BC5 2 NAG U . ? NAG B 600 . ? 1_555 ? 53 BC5 2 MAN W . ? MAN B 602 . ? 1_555 ? 54 BC6 2 PRO B 370 ? PRO B 370 . ? 1_555 ? 55 BC6 2 NAG V . ? NAG B 601 . ? 1_555 ? 56 BC7 2 ASN B 332 ? ASN B 332 . ? 1_555 ? 57 BC7 2 ASP B 524 ? ASP B 524 . ? 1_555 ? 58 BC8 5 ASP A 110 ? ASP A 110 . ? 1_555 ? 59 BC8 5 THR A 184 ? THR A 184 . ? 1_555 ? 60 BC8 5 PHE A 186 ? PHE A 186 . ? 1_555 ? 61 BC8 5 ASP A 188 ? ASP A 188 . ? 1_555 ? 62 BC8 5 SER A 190 ? SER A 190 . ? 1_555 ? 63 BC9 5 ASP B 110 ? ASP B 110 . ? 1_555 ? 64 BC9 5 THR B 184 ? THR B 184 . ? 1_555 ? 65 BC9 5 PHE B 186 ? PHE B 186 . ? 1_555 ? 66 BC9 5 ASP B 188 ? ASP B 188 . ? 1_555 ? 67 BC9 5 SER B 190 ? SER B 190 . ? 1_555 ? 68 CC1 4 ASN A 95 ? ASN A 95 . ? 1_555 ? 69 CC1 4 ARG A 504 ? ARG A 504 . ? 1_555 ? 70 CC1 4 ARG A 506 ? ARG A 506 . ? 1_555 ? 71 CC1 4 NAG C . ? NAG A 596 . ? 1_555 ? 72 CC2 5 ASN B 95 ? ASN B 95 . ? 1_555 ? 73 CC2 5 ARG B 96 ? ARG B 96 . ? 1_555 ? 74 CC2 5 ARG B 504 ? ARG B 504 . ? 1_555 ? 75 CC2 5 ARG B 506 ? ARG B 506 . ? 1_555 ? 76 CC2 5 NAG Q . ? NAG B 596 . ? 1_555 ? 77 CC3 17 MET A 101 ? MET A 101 . ? 1_555 ? 78 CC3 17 GLY A 104 ? GLY A 104 . ? 1_555 ? 79 CC3 17 GLN A 105 ? GLN A 105 . ? 1_555 ? 80 CC3 17 ASP A 108 ? ASP A 108 . ? 1_555 ? 81 CC3 17 ASP A 112 ? ASP A 112 . ? 1_555 ? 82 CC3 17 ALA A 114 ? ALA A 114 . ? 1_555 ? 83 CC3 17 GLU A 258 ? GLU A 258 . ? 1_555 ? 84 CC3 17 THR A 344 ? THR A 344 . ? 1_555 ? 85 CC3 17 PHE A 347 ? PHE A 347 . ? 1_555 ? 86 CC3 17 ARG A 348 ? ARG A 348 . ? 1_555 ? 87 CC3 17 GLY A 350 ? GLY A 350 . ? 1_555 ? 88 CC3 17 HIS A 351 ? HIS A 351 . ? 1_555 ? 89 CC3 17 VAL A 354 ? VAL A 354 . ? 1_555 ? 90 CC3 17 PHE A 380 ? PHE A 380 . ? 1_555 ? 91 CC3 17 ILE A 436 ? ILE A 436 . ? 1_555 ? 92 CC3 17 ARG A 440 ? ARG A 440 . ? 1_555 ? 93 CC3 17 FMT P . ? FMT A 3003 . ? 1_555 ? 94 CC4 21 MET B 101 ? MET B 101 . ? 1_555 ? 95 CC4 21 GLY B 104 ? GLY B 104 . ? 1_555 ? 96 CC4 21 GLN B 105 ? GLN B 105 . ? 1_555 ? 97 CC4 21 ASP B 108 ? ASP B 108 . ? 1_555 ? 98 CC4 21 ASP B 112 ? ASP B 112 . ? 1_555 ? 99 CC4 21 PHE B 113 ? PHE B 113 . ? 1_555 ? 100 CC4 21 ALA B 114 ? ALA B 114 . ? 1_555 ? 101 CC4 21 GLU B 116 ? GLU B 116 . ? 1_555 ? 102 CC4 21 ARG B 255 ? ARG B 255 . ? 1_555 ? 103 CC4 21 GLU B 258 ? GLU B 258 . ? 1_555 ? 104 CC4 21 THR B 344 ? THR B 344 . ? 1_555 ? 105 CC4 21 PHE B 347 ? PHE B 347 . ? 1_555 ? 106 CC4 21 ARG B 348 ? ARG B 348 . ? 1_555 ? 107 CC4 21 HIS B 351 ? HIS B 351 . ? 1_555 ? 108 CC4 21 VAL B 354 ? VAL B 354 . ? 1_555 ? 109 CC4 21 PHE B 380 ? PHE B 380 . ? 1_555 ? 110 CC4 21 LEU B 417 ? LEU B 417 . ? 1_555 ? 111 CC4 21 GLN B 423 ? GLN B 423 . ? 1_555 ? 112 CC4 21 ARG B 440 ? ARG B 440 . ? 1_555 ? 113 CC4 21 FMT DA . ? FMT B 3006 . ? 1_555 ? 114 CC4 21 HOH FA . ? HOH B 3027 . ? 1_555 ? 115 CC5 3 ARG A 397 ? ARG A 397 . ? 1_555 ? 116 CC5 3 ILE A 559 ? ILE A 559 . ? 1_555 ? 117 CC5 3 THR A 560 ? THR A 560 . ? 1_555 ? 118 CC6 5 TRP A 46 ? TRP A 46 . ? 1_555 ? 119 CC6 5 LEU A 47 ? LEU A 47 . ? 1_555 ? 120 CC6 5 ASN A 341 ? ASN A 341 . ? 1_555 ? 121 CC6 5 VAL A 342 ? VAL A 342 . ? 1_555 ? 122 CC6 5 TRP A 452 ? TRP A 452 . ? 1_555 ? 123 CC7 3 HIS A 109 ? HIS A 109 . ? 1_555 ? 124 CC7 3 ARG A 255 ? ARG A 255 . ? 1_555 ? 125 CC7 3 HEM M . ? HEM A 605 . ? 1_555 ? 126 CC8 3 GLU B 363 ? GLU B 363 . ? 1_555 ? 127 CC8 3 TYR B 365 ? TYR B 365 . ? 1_555 ? 128 CC8 3 THR B 560 ? THR B 560 . ? 1_555 ? 129 CC9 8 ALA B 44 ? ALA B 44 . ? 1_555 ? 130 CC9 8 ARG B 45 ? ARG B 45 . ? 1_555 ? 131 CC9 8 TRP B 46 ? TRP B 46 . ? 1_555 ? 132 CC9 8 LEU B 47 ? LEU B 47 . ? 1_555 ? 133 CC9 8 SER B 340 ? SER B 340 . ? 1_555 ? 134 CC9 8 ASN B 341 ? ASN B 341 . ? 1_555 ? 135 CC9 8 VAL B 342 ? VAL B 342 . ? 1_555 ? 136 CC9 8 TRP B 452 ? TRP B 452 . ? 1_555 ? 137 DC1 4 GLN B 105 ? GLN B 105 . ? 1_555 ? 138 DC1 4 HIS B 109 ? HIS B 109 . ? 1_555 ? 139 DC1 4 ARG B 255 ? ARG B 255 . ? 1_555 ? 140 DC1 4 HEM AA . ? HEM B 605 . ? 1_555 ? # _database_PDB_matrix.entry_id 2IKC _database_PDB_matrix.origx[1][1] 1.000000 _database_PDB_matrix.origx[1][2] 0.000000 _database_PDB_matrix.origx[1][3] 0.000000 _database_PDB_matrix.origx[2][1] 0.000000 _database_PDB_matrix.origx[2][2] 1.000000 _database_PDB_matrix.origx[2][3] 0.000000 _database_PDB_matrix.origx[3][1] 0.000000 _database_PDB_matrix.origx[3][2] 0.000000 _database_PDB_matrix.origx[3][3] 1.000000 _database_PDB_matrix.origx_vector[1] 0.00000 _database_PDB_matrix.origx_vector[2] 0.00000 _database_PDB_matrix.origx_vector[3] 0.00000 # _atom_sites.entry_id 2IKC _atom_sites.fract_transf_matrix[1][1] 0.016926 _atom_sites.fract_transf_matrix[1][2] -0.004406 _atom_sites.fract_transf_matrix[1][3] -0.001497 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.014235 _atom_sites.fract_transf_matrix[2][3] -0.000854 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.011924 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C CA FE N O S # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . SER A 1 1 ? -12.027 27.698 4.401 1.00 78.23 ? 1 SER A N 1 ATOM 2 C CA . SER A 1 1 ? -10.656 28.084 4.574 1.00 78.46 ? 1 SER A CA 1 ATOM 3 C C . SER A 1 1 ? -9.969 28.258 3.239 1.00 79.15 ? 1 SER A C 1 ATOM 4 O O . SER A 1 1 ? -9.547 27.331 2.553 1.00 78.63 ? 1 SER A O 1 ATOM 5 C CB . SER A 1 1 ? -9.847 27.113 5.414 1.00 78.43 ? 1 SER A CB 1 ATOM 6 O OG . SER A 1 1 ? -9.788 27.545 6.766 1.00 77.89 ? 1 SER A OG 1 ATOM 7 N N . TRP A 1 2 ? -9.866 29.486 2.937 1.00 80.27 ? 2 TRP A N 1 ATOM 8 C CA . TRP A 1 2 ? -9.167 29.928 1.775 1.00 80.85 ? 2 TRP A CA 1 ATOM 9 C C . TRP A 1 2 ? -8.141 30.928 2.378 1.00 81.17 ? 2 TRP A C 1 ATOM 10 O O . TRP A 1 2 ? -8.512 32.063 2.707 1.00 80.09 ? 2 TRP A O 1 ATOM 11 C CB . TRP A 1 2 ? -10.119 30.557 0.745 1.00 82.94 ? 2 TRP A CB 1 ATOM 12 C CG . TRP A 1 2 ? -10.654 29.697 -0.373 1.00 84.86 ? 2 TRP A CG 1 ATOM 13 C CD1 . TRP A 1 2 ? -10.283 28.442 -0.783 1.00 85.04 ? 2 TRP A CD1 1 ATOM 14 C CD2 . TRP A 1 2 ? -11.690 30.121 -1.280 1.00 85.35 ? 2 TRP A CD2 1 ATOM 15 N NE1 . TRP A 1 2 ? -11.016 28.065 -1.888 1.00 85.38 ? 2 TRP A NE1 1 ATOM 16 C CE2 . TRP A 1 2 ? -11.885 29.075 -2.213 1.00 85.68 ? 2 TRP A CE2 1 ATOM 17 C CE3 . TRP A 1 2 ? -12.467 31.285 -1.396 1.00 85.69 ? 2 TRP A CE3 1 ATOM 18 C CZ2 . TRP A 1 2 ? -12.828 29.158 -3.251 1.00 85.62 ? 2 TRP A CZ2 1 ATOM 19 C CZ3 . TRP A 1 2 ? -13.405 31.366 -2.430 1.00 85.85 ? 2 TRP A CZ3 1 ATOM 20 C CH2 . TRP A 1 2 ? -13.575 30.307 -3.343 1.00 85.81 ? 2 TRP A CH2 1 ATOM 21 N N . GLU A 1 3 ? -6.875 30.492 2.529 1.00 81.40 ? 3 GLU A N 1 ATOM 22 C CA . GLU A 1 3 ? -5.784 31.230 3.152 1.00 81.49 ? 3 GLU A CA 1 ATOM 23 C C . GLU A 1 3 ? -4.399 30.702 2.822 1.00 81.19 ? 3 GLU A C 1 ATOM 24 O O . GLU A 1 3 ? -4.241 29.641 2.236 1.00 81.00 ? 3 GLU A O 1 ATOM 25 C CB . GLU A 1 3 ? -5.862 31.125 4.692 1.00 82.90 ? 3 GLU A CB 1 ATOM 26 C CG . GLU A 1 3 ? -6.228 32.429 5.433 1.00 84.96 ? 3 GLU A CG 1 ATOM 27 C CD . GLU A 1 3 ? -5.117 33.004 6.336 1.00 86.01 ? 3 GLU A CD 1 ATOM 28 O OE1 . GLU A 1 3 ? -4.764 32.354 7.335 1.00 86.47 ? 3 GLU A OE1 1 ATOM 29 O OE2 . GLU A 1 3 ? -4.617 34.108 6.027 1.00 86.80 ? 3 GLU A OE2 1 ATOM 30 N N . VAL A 1 4 ? -3.387 31.454 3.236 1.00 80.37 ? 4 VAL A N 1 ATOM 31 C CA . VAL A 1 4 ? -1.951 31.227 2.967 1.00 79.76 ? 4 VAL A CA 1 ATOM 32 C C . VAL A 1 4 ? -1.203 30.145 3.756 1.00 79.47 ? 4 VAL A C 1 ATOM 33 O O . VAL A 1 4 ? -1.693 29.632 4.767 1.00 79.86 ? 4 VAL A O 1 ATOM 34 C CB . VAL A 1 4 ? -1.188 32.540 3.231 1.00 79.64 ? 4 VAL A CB 1 ATOM 35 C CG1 . VAL A 1 4 ? -0.450 32.977 1.969 1.00 78.81 ? 4 VAL A CG1 1 ATOM 36 C CG2 . VAL A 1 4 ? -2.143 33.641 3.700 1.00 78.97 ? 4 VAL A CG2 1 ATOM 37 N N . GLY A 1 5 ? 0.059 29.852 3.316 1.00 78.86 ? 5 GLY A N 1 ATOM 38 C CA . GLY A 1 5 ? 0.885 28.816 4.028 1.00 76.87 ? 5 GLY A CA 1 ATOM 39 C C . GLY A 1 5 ? 2.372 28.664 3.625 1.00 75.00 ? 5 GLY A C 1 ATOM 40 O O . GLY A 1 5 ? 2.802 29.171 2.589 1.00 75.70 ? 5 GLY A O 1 ATOM 41 N N . CYS A 1 6 ? 3.194 27.934 4.470 1.00 72.57 ? 6 CYS A N 1 ATOM 42 C CA . CYS A 1 6 ? 4.618 27.630 4.300 1.00 70.54 ? 6 CYS A CA 1 ATOM 43 C C . CYS A 1 6 ? 4.880 27.081 2.914 1.00 70.73 ? 6 CYS A C 1 ATOM 44 O O . CYS A 1 6 ? 4.445 25.996 2.539 1.00 71.30 ? 6 CYS A O 1 ATOM 45 C CB . CYS A 1 6 ? 5.092 26.611 5.344 1.00 66.62 ? 6 CYS A CB 1 ATOM 46 S SG . CYS A 1 6 ? 4.679 27.046 7.065 1.00 61.30 ? 6 CYS A SG 1 ATOM 47 N N . GLY A 1 7 ? 5.614 27.863 2.170 1.00 70.58 ? 7 GLY A N 1 ATOM 48 C CA . GLY A 1 7 ? 6.020 27.447 0.865 1.00 70.11 ? 7 GLY A CA 1 ATOM 49 C C . GLY A 1 7 ? 7.474 27.016 1.011 1.00 69.33 ? 7 GLY A C 1 ATOM 50 O O . GLY A 1 7 ? 8.394 27.800 0.804 1.00 69.86 ? 7 GLY A O 1 ATOM 51 N N . ALA A 1 8 ? 7.664 25.709 1.358 1.00 68.25 ? 8 ALA A N 1 ATOM 52 C CA . ALA A 1 8 ? 8.976 25.033 1.575 1.00 67.17 ? 8 ALA A CA 1 ATOM 53 C C . ALA A 1 8 ? 9.580 24.382 0.292 1.00 66.50 ? 8 ALA A C 1 ATOM 54 O O . ALA A 1 8 ? 8.971 24.474 -0.764 1.00 65.94 ? 8 ALA A O 1 ATOM 55 C CB . ALA A 1 8 ? 8.837 23.977 2.660 1.00 66.43 ? 8 ALA A CB 1 ATOM 56 N N . PRO A 1 9 ? 10.789 23.708 0.385 1.00 65.66 ? 9 PRO A N 1 ATOM 57 C CA . PRO A 1 9 ? 11.506 23.180 -0.921 1.00 64.50 ? 9 PRO A CA 1 ATOM 58 C C . PRO A 1 9 ? 10.804 22.365 -1.984 1.00 62.95 ? 9 PRO A C 1 ATOM 59 O O . PRO A 1 9 ? 10.802 21.131 -1.871 1.00 63.67 ? 9 PRO A O 1 ATOM 60 C CB . PRO A 1 9 ? 12.707 22.474 -0.389 1.00 64.67 ? 9 PRO A CB 1 ATOM 61 C CG . PRO A 1 9 ? 13.096 23.389 0.717 1.00 64.97 ? 9 PRO A CG 1 ATOM 62 C CD . PRO A 1 9 ? 11.907 24.162 1.233 1.00 65.10 ? 9 PRO A CD 1 ATOM 63 N N . VAL A 1 10 ? 10.221 22.940 -3.026 1.00 59.57 ? 10 VAL A N 1 ATOM 64 C CA . VAL A 1 10 ? 9.556 21.997 -3.930 1.00 55.56 ? 10 VAL A CA 1 ATOM 65 C C . VAL A 1 10 ? 10.023 22.146 -5.363 1.00 54.62 ? 10 VAL A C 1 ATOM 66 O O . VAL A 1 10 ? 10.128 23.285 -5.845 1.00 54.93 ? 10 VAL A O 1 ATOM 67 C CB . VAL A 1 10 ? 8.034 22.181 -3.946 1.00 55.32 ? 10 VAL A CB 1 ATOM 68 C CG1 . VAL A 1 10 ? 7.411 21.519 -2.725 1.00 54.65 ? 10 VAL A CG1 1 ATOM 69 C CG2 . VAL A 1 10 ? 7.665 23.658 -4.019 1.00 55.20 ? 10 VAL A CG2 1 ATOM 70 N N . PRO A 1 11 ? 10.297 21.037 -6.068 1.00 53.30 ? 11 PRO A N 1 ATOM 71 C CA . PRO A 1 11 ? 10.728 21.224 -7.445 1.00 51.04 ? 11 PRO A CA 1 ATOM 72 C C . PRO A 1 11 ? 9.682 22.051 -8.166 1.00 49.80 ? 11 PRO A C 1 ATOM 73 O O . PRO A 1 11 ? 8.501 21.692 -8.223 1.00 50.46 ? 11 PRO A O 1 ATOM 74 C CB . PRO A 1 11 ? 10.823 19.798 -7.959 1.00 50.88 ? 11 PRO A CB 1 ATOM 75 C CG . PRO A 1 11 ? 11.358 19.094 -6.761 1.00 52.01 ? 11 PRO A CG 1 ATOM 76 C CD . PRO A 1 11 ? 10.337 19.608 -5.725 1.00 52.86 ? 11 PRO A CD 1 ATOM 77 N N . LEU A 1 12 ? 10.130 23.169 -8.711 1.00 48.78 ? 12 LEU A N 1 ATOM 78 C CA . LEU A 1 12 ? 9.252 24.082 -9.410 1.00 48.43 ? 12 LEU A CA 1 ATOM 79 C C . LEU A 1 12 ? 9.351 23.832 -10.906 1.00 47.75 ? 12 LEU A C 1 ATOM 80 O O . LEU A 1 12 ? 10.454 23.653 -11.430 1.00 48.56 ? 12 LEU A O 1 ATOM 81 C CB . LEU A 1 12 ? 9.662 25.514 -9.048 1.00 48.21 ? 12 LEU A CB 1 ATOM 82 C CG . LEU A 1 12 ? 8.667 26.639 -9.333 1.00 48.06 ? 12 LEU A CG 1 ATOM 83 C CD1 . LEU A 1 12 ? 7.916 27.027 -8.076 1.00 46.88 ? 12 LEU A CD1 1 ATOM 84 C CD2 . LEU A 1 12 ? 9.386 27.832 -9.917 1.00 47.22 ? 12 LEU A CD2 1 ATOM 85 N N . VAL A 1 13 ? 8.200 23.834 -11.622 1.00 45.18 ? 13 VAL A N 1 ATOM 86 C CA . VAL A 1 13 ? 8.183 23.662 -13.073 1.00 43.92 ? 13 VAL A CA 1 ATOM 87 C C . VAL A 1 13 ? 7.112 24.490 -13.745 1.00 43.19 ? 13 VAL A C 1 ATOM 88 O O . VAL A 1 13 ? 6.171 24.977 -13.127 1.00 43.98 ? 13 VAL A O 1 ATOM 89 C CB . VAL A 1 13 ? 7.955 22.216 -13.475 1.00 44.94 ? 13 VAL A CB 1 ATOM 90 C CG1 . VAL A 1 13 ? 9.264 21.462 -13.509 1.00 45.39 ? 13 VAL A CG1 1 ATOM 91 C CG2 . VAL A 1 13 ? 6.962 21.553 -12.527 1.00 45.45 ? 13 VAL A CG2 1 ATOM 92 N N . LYS A 1 14 ? 7.266 24.595 -15.037 1.00 42.03 ? 14 LYS A N 1 ATOM 93 C CA . LYS A 1 14 ? 6.388 25.371 -15.866 1.00 39.16 ? 14 LYS A CA 1 ATOM 94 C C . LYS A 1 14 ? 5.455 24.442 -16.608 1.00 36.95 ? 14 LYS A C 1 ATOM 95 O O . LYS A 1 14 ? 5.890 23.521 -17.302 1.00 36.92 ? 14 LYS A O 1 ATOM 96 C CB . LYS A 1 14 ? 7.245 26.197 -16.828 1.00 40.75 ? 14 LYS A CB 1 ATOM 97 C CG . LYS A 1 14 ? 6.542 27.337 -17.534 1.00 44.18 ? 14 LYS A CG 1 ATOM 98 C CD . LYS A 1 14 ? 7.326 28.635 -17.455 1.00 45.82 ? 14 LYS A CD 1 ATOM 99 C CE . LYS A 1 14 ? 7.522 29.086 -16.017 1.00 46.25 ? 14 LYS A CE 1 ATOM 100 N NZ . LYS A 1 14 ? 8.109 30.453 -15.944 1.00 46.55 ? 14 LYS A NZ 1 ATOM 101 N N . CYS A 1 15 ? 4.165 24.704 -16.464 1.00 34.21 ? 15 CYS A N 1 ATOM 102 C CA . CYS A 1 15 ? 3.171 23.896 -17.130 1.00 30.81 ? 15 CYS A CA 1 ATOM 103 C C . CYS A 1 15 ? 3.172 24.176 -18.615 1.00 31.17 ? 15 CYS A C 1 ATOM 104 O O . CYS A 1 15 ? 2.878 25.293 -19.071 1.00 30.51 ? 15 CYS A O 1 ATOM 105 C CB . CYS A 1 15 ? 1.796 24.157 -16.527 1.00 25.51 ? 15 CYS A CB 1 ATOM 106 S SG . CYS A 1 15 ? 1.795 23.750 -14.756 1.00 16.93 ? 15 CYS A SG 1 ATOM 107 N N . ASP A 1 16 ? 3.542 23.142 -19.359 1.00 32.84 ? 16 ASP A N 1 ATOM 108 C CA . ASP A 1 16 ? 3.579 23.218 -20.799 1.00 34.40 ? 16 ASP A CA 1 ATOM 109 C C . ASP A 1 16 ? 2.136 23.622 -21.099 1.00 34.36 ? 16 ASP A C 1 ATOM 110 O O . ASP A 1 16 ? 1.881 24.707 -21.627 1.00 34.28 ? 16 ASP A O 1 ATOM 111 C CB . ASP A 1 16 ? 3.945 21.839 -21.371 1.00 35.17 ? 16 ASP A CB 1 ATOM 112 C CG . ASP A 1 16 ? 4.410 21.908 -22.808 1.00 36.16 ? 16 ASP A CG 1 ATOM 113 O OD1 . ASP A 1 16 ? 3.597 22.319 -23.659 1.00 37.63 ? 16 ASP A OD1 1 ATOM 114 O OD2 . ASP A 1 16 ? 5.580 21.561 -23.089 1.00 36.85 ? 16 ASP A OD2 1 ATOM 115 N N . GLU A 1 17 ? 1.202 22.758 -20.705 1.00 34.04 ? 17 GLU A N 1 ATOM 116 C CA . GLU A 1 17 ? -0.247 22.991 -20.839 1.00 33.39 ? 17 GLU A CA 1 ATOM 117 C C . GLU A 1 17 ? -0.980 22.346 -22.004 1.00 32.46 ? 17 GLU A C 1 ATOM 118 O O . GLU A 1 17 ? -2.205 22.432 -22.076 1.00 31.09 ? 17 GLU A O 1 ATOM 119 C CB . GLU A 1 17 ? -0.572 24.495 -20.833 1.00 34.50 ? 17 GLU A CB 1 ATOM 120 C CG . GLU A 1 17 ? -2.072 24.817 -20.683 1.00 37.10 ? 17 GLU A CG 1 ATOM 121 C CD . GLU A 1 17 ? -2.570 24.644 -19.258 1.00 37.51 ? 17 GLU A CD 1 ATOM 122 O OE1 . GLU A 1 17 ? -3.782 24.831 -19.024 1.00 38.24 ? 17 GLU A OE1 1 ATOM 123 O OE2 . GLU A 1 17 ? -1.745 24.330 -18.374 1.00 38.22 ? 17 GLU A OE2 1 ATOM 124 N N . ASN A 1 18 ? -0.258 21.714 -22.918 1.00 31.35 ? 18 ASN A N 1 ATOM 125 C CA . ASN A 1 18 ? -0.920 21.079 -24.042 1.00 30.05 ? 18 ASN A CA 1 ATOM 126 C C . ASN A 1 18 ? -0.217 19.800 -24.413 1.00 27.48 ? 18 ASN A C 1 ATOM 127 O O . ASN A 1 18 ? -0.302 19.320 -25.540 1.00 27.78 ? 18 ASN A O 1 ATOM 128 C CB . ASN A 1 18 ? -0.990 22.023 -25.240 1.00 34.17 ? 18 ASN A CB 1 ATOM 129 C CG . ASN A 1 18 ? -2.071 23.088 -25.079 1.00 37.82 ? 18 ASN A CG 1 ATOM 130 O OD1 . ASN A 1 18 ? -1.833 24.149 -24.501 1.00 38.55 ? 18 ASN A OD1 1 ATOM 131 N ND2 . ASN A 1 18 ? -3.282 22.788 -25.563 1.00 40.35 ? 18 ASN A ND2 1 ATOM 132 N N . SER A 1 19 ? 0.476 19.263 -23.418 1.00 24.14 ? 19 SER A N 1 ATOM 133 C CA . SER A 1 19 ? 1.214 18.022 -23.530 1.00 20.15 ? 19 SER A CA 1 ATOM 134 C C . SER A 1 19 ? 0.230 16.912 -23.204 1.00 16.61 ? 19 SER A C 1 ATOM 135 O O . SER A 1 19 ? -0.424 16.942 -22.167 1.00 16.19 ? 19 SER A O 1 ATOM 136 C CB . SER A 1 19 ? 2.355 18.014 -22.515 1.00 20.02 ? 19 SER A CB 1 ATOM 137 O OG . SER A 1 19 ? 2.738 16.695 -22.170 1.00 19.64 ? 19 SER A OG 1 ATOM 138 N N . PRO A 1 20 ? 0.096 15.924 -24.090 1.00 13.88 ? 20 PRO A N 1 ATOM 139 C CA . PRO A 1 20 ? -0.846 14.843 -23.792 1.00 13.53 ? 20 PRO A CA 1 ATOM 140 C C . PRO A 1 20 ? -0.287 13.947 -22.685 1.00 11.69 ? 20 PRO A C 1 ATOM 141 O O . PRO A 1 20 ? -0.885 12.920 -22.339 1.00 12.40 ? 20 PRO A O 1 ATOM 142 C CB . PRO A 1 20 ? -0.950 14.088 -25.123 1.00 13.51 ? 20 PRO A CB 1 ATOM 143 C CG . PRO A 1 20 ? -0.464 15.079 -26.154 1.00 14.74 ? 20 PRO A CG 1 ATOM 144 C CD . PRO A 1 20 ? 0.650 15.794 -25.446 1.00 14.09 ? 20 PRO A CD 1 ATOM 145 N N . TYR A 1 21 ? 0.852 14.341 -22.120 1.00 7.53 ? 21 TYR A N 1 ATOM 146 C CA . TYR A 1 21 ? 1.489 13.519 -21.110 1.00 4.22 ? 21 TYR A CA 1 ATOM 147 C C . TYR A 1 21 ? 1.547 14.069 -19.713 1.00 3.14 ? 21 TYR A C 1 ATOM 148 O O . TYR A 1 21 ? 1.772 15.259 -19.518 1.00 2.42 ? 21 TYR A O 1 ATOM 149 C CB . TYR A 1 21 ? 2.887 13.162 -21.596 1.00 3.05 ? 21 TYR A CB 1 ATOM 150 C CG . TYR A 1 21 ? 2.821 12.517 -22.952 1.00 3.31 ? 21 TYR A CG 1 ATOM 151 C CD1 . TYR A 1 21 ? 1.751 11.688 -23.273 1.00 5.07 ? 21 TYR A CD1 1 ATOM 152 C CD2 . TYR A 1 21 ? 3.800 12.734 -23.916 1.00 2.14 ? 21 TYR A CD2 1 ATOM 153 C CE1 . TYR A 1 21 ? 1.645 11.089 -24.510 1.00 6.35 ? 21 TYR A CE1 1 ATOM 154 C CE2 . TYR A 1 21 ? 3.708 12.132 -25.174 1.00 4.03 ? 21 TYR A CE2 1 ATOM 155 C CZ . TYR A 1 21 ? 2.620 11.305 -25.461 1.00 5.62 ? 21 TYR A CZ 1 ATOM 156 O OH . TYR A 1 21 ? 2.482 10.663 -26.679 1.00 5.85 ? 21 TYR A OH 1 ATOM 157 N N . ARG A 1 22 ? 1.321 13.184 -18.742 1.00 3.35 ? 22 ARG A N 1 ATOM 158 C CA . ARG A 1 22 ? 1.372 13.548 -17.327 1.00 3.62 ? 22 ARG A CA 1 ATOM 159 C C . ARG A 1 22 ? 2.786 14.030 -17.002 1.00 3.65 ? 22 ARG A C 1 ATOM 160 O O . ARG A 1 22 ? 3.759 13.595 -17.623 1.00 4.22 ? 22 ARG A O 1 ATOM 161 C CB . ARG A 1 22 ? 1.122 12.331 -16.422 1.00 3.14 ? 22 ARG A CB 1 ATOM 162 C CG . ARG A 1 22 ? -0.293 11.812 -16.236 1.00 2.95 ? 22 ARG A CG 1 ATOM 163 C CD . ARG A 1 22 ? -0.226 10.618 -15.260 1.00 2.91 ? 22 ARG A CD 1 ATOM 164 N NE . ARG A 1 22 ? -1.505 9.942 -15.038 1.00 2.47 ? 22 ARG A NE 1 ATOM 165 C CZ . ARG A 1 22 ? -2.454 10.365 -14.206 1.00 2.00 ? 22 ARG A CZ 1 ATOM 166 N NH1 . ARG A 1 22 ? -2.281 11.471 -13.496 1.00 2.00 ? 22 ARG A NH1 1 ATOM 167 N NH2 . ARG A 1 22 ? -3.582 9.685 -14.093 1.00 2.00 ? 22 ARG A NH2 1 ATOM 168 N N . THR A 1 23 ? 2.939 14.979 -16.055 1.00 3.70 ? 23 THR A N 1 ATOM 169 C CA . THR A 1 23 ? 4.322 15.265 -15.725 1.00 3.75 ? 23 THR A CA 1 ATOM 170 C C . THR A 1 23 ? 4.725 14.212 -14.769 1.00 5.61 ? 23 THR A C 1 ATOM 171 O O . THR A 1 23 ? 3.908 13.673 -14.035 1.00 5.29 ? 23 THR A O 1 ATOM 172 C CB . THR A 1 23 ? 4.606 16.635 -14.997 1.00 5.96 ? 23 THR A CB 1 ATOM 173 O OG1 . THR A 1 23 ? 4.017 16.579 -13.691 1.00 6.69 ? 23 THR A OG1 1 ATOM 174 C CG2 . THR A 1 23 ? 4.019 17.788 -15.777 1.00 6.68 ? 23 THR A CG2 1 ATOM 175 N N . ILE A 1 24 ? 5.992 13.887 -14.777 1.00 5.34 ? 24 ILE A N 1 ATOM 176 C CA . ILE A 1 24 ? 6.353 13.071 -13.455 1.00 5.19 ? 24 ILE A CA 1 ATOM 177 C C . ILE A 1 24 ? 6.187 13.440 -11.990 1.00 5.83 ? 24 ILE A C 1 ATOM 178 O O . ILE A 1 24 ? 5.974 12.584 -11.128 1.00 6.58 ? 24 ILE A O 1 ATOM 179 C CB . ILE A 1 24 ? 7.826 12.734 -13.795 1.00 5.03 ? 24 ILE A CB 1 ATOM 180 C CG1 . ILE A 1 24 ? 7.902 11.291 -14.290 1.00 4.90 ? 24 ILE A CG1 1 ATOM 181 C CG2 . ILE A 1 24 ? 8.732 12.943 -12.583 1.00 6.52 ? 24 ILE A CG2 1 ATOM 182 C CD1 . ILE A 1 24 ? 9.102 11.009 -15.156 1.00 4.03 ? 24 ILE A CD1 1 ATOM 183 N N . THR A 1 25 ? 6.262 14.740 -11.739 1.00 5.97 ? 25 THR A N 1 ATOM 184 C CA . THR A 1 25 ? 6.133 15.313 -10.409 1.00 6.01 ? 25 THR A CA 1 ATOM 185 C C . THR A 1 25 ? 4.681 15.355 -9.950 1.00 6.15 ? 25 THR A C 1 ATOM 186 O O . THR A 1 25 ? 4.392 15.561 -8.769 1.00 5.33 ? 25 THR A O 1 ATOM 187 C CB . THR A 1 25 ? 6.689 16.749 -10.406 1.00 7.65 ? 25 THR A CB 1 ATOM 188 O OG1 . THR A 1 25 ? 7.974 16.764 -9.769 1.00 9.01 ? 25 THR A OG1 1 ATOM 189 C CG2 . THR A 1 25 ? 5.726 17.710 -9.704 1.00 8.39 ? 25 THR A CG2 1 ATOM 190 N N . GLY A 1 26 ? 3.766 15.166 -10.890 1.00 6.56 ? 26 GLY A N 1 ATOM 191 C CA . GLY A 1 26 ? 2.361 15.215 -10.543 1.00 6.12 ? 26 GLY A CA 1 ATOM 192 C C . GLY A 1 26 ? 1.845 16.628 -10.733 1.00 5.76 ? 26 GLY A C 1 ATOM 193 O O . GLY A 1 26 ? 0.630 16.846 -10.780 1.00 6.34 ? 26 GLY A O 1 ATOM 194 N N . ASP A 1 27 ? 2.735 17.618 -10.865 1.00 4.10 ? 27 ASP A N 1 ATOM 195 C CA . ASP A 1 27 ? 2.366 18.982 -11.109 1.00 2.80 ? 27 ASP A CA 1 ATOM 196 C C . ASP A 1 27 ? 1.662 19.221 -12.435 1.00 2.93 ? 27 ASP A C 1 ATOM 197 O O . ASP A 1 27 ? 1.828 18.495 -13.425 1.00 3.13 ? 27 ASP A O 1 ATOM 198 C CB . ASP A 1 27 ? 3.621 19.878 -11.192 1.00 2.91 ? 27 ASP A CB 1 ATOM 199 C CG . ASP A 1 27 ? 4.123 20.439 -9.875 1.00 3.07 ? 27 ASP A CG 1 ATOM 200 O OD1 . ASP A 1 27 ? 3.271 20.752 -9.015 1.00 3.83 ? 27 ASP A OD1 1 ATOM 201 O OD2 . ASP A 1 27 ? 5.349 20.557 -9.710 1.00 3.38 ? 27 ASP A OD2 1 ATOM 202 N N . CYS A 1 28 ? 0.859 20.286 -12.436 1.00 2.77 ? 28 CYS A N 1 ATOM 203 C CA . CYS A 1 28 ? 0.211 20.742 -13.637 1.00 3.14 ? 28 CYS A CA 1 ATOM 204 C C . CYS A 1 28 ? -1.041 19.952 -13.986 1.00 2.91 ? 28 CYS A C 1 ATOM 205 O O . CYS A 1 28 ? -1.700 20.284 -14.970 1.00 3.07 ? 28 CYS A O 1 ATOM 206 C CB . CYS A 1 28 ? 1.207 20.708 -14.794 1.00 5.20 ? 28 CYS A CB 1 ATOM 207 S SG . CYS A 1 28 ? 2.705 21.712 -14.514 1.00 12.38 ? 28 CYS A SG 1 ATOM 208 N N . ASN A 1 29 ? -1.388 18.918 -13.230 1.00 2.97 ? 29 ASN A N 1 ATOM 209 C CA . ASN A 1 29 ? -2.598 18.169 -13.581 1.00 3.87 ? 29 ASN A CA 1 ATOM 210 C C . ASN A 1 29 ? -3.758 19.154 -13.589 1.00 2.91 ? 29 ASN A C 1 ATOM 211 O O . ASN A 1 29 ? -4.495 19.292 -14.574 1.00 2.00 ? 29 ASN A O 1 ATOM 212 C CB . ASN A 1 29 ? -2.868 17.049 -12.564 1.00 3.73 ? 29 ASN A CB 1 ATOM 213 C CG . ASN A 1 29 ? -4.289 16.501 -12.656 1.00 4.13 ? 29 ASN A CG 1 ATOM 214 O OD1 . ASN A 1 29 ? -5.268 17.222 -12.414 1.00 4.94 ? 29 ASN A OD1 1 ATOM 215 N ND2 . ASN A 1 29 ? -4.410 15.224 -13.004 1.00 2.18 ? 29 ASN A ND2 1 ATOM 216 N N . ASN A 1 30 ? -3.890 19.847 -12.464 1.00 5.26 ? 30 ASN A N 1 ATOM 217 C CA . ASN A 1 30 ? -4.929 20.836 -12.280 1.00 5.43 ? 30 ASN A CA 1 ATOM 218 C C . ASN A 1 30 ? -4.487 22.152 -12.868 1.00 7.11 ? 30 ASN A C 1 ATOM 219 O O . ASN A 1 30 ? -3.426 22.686 -12.518 1.00 6.20 ? 30 ASN A O 1 ATOM 220 C CB . ASN A 1 30 ? -5.222 21.052 -10.809 1.00 4.71 ? 30 ASN A CB 1 ATOM 221 C CG . ASN A 1 30 ? -6.327 22.050 -10.597 1.00 4.16 ? 30 ASN A CG 1 ATOM 222 O OD1 . ASN A 1 30 ? -6.414 23.044 -11.316 1.00 2.16 ? 30 ASN A OD1 1 ATOM 223 N ND2 . ASN A 1 30 ? -7.182 21.800 -9.604 1.00 4.67 ? 30 ASN A ND2 1 ATOM 224 N N . ARG A 1 31 ? -5.336 22.674 -13.744 1.00 9.58 ? 31 ARG A N 1 ATOM 225 C CA . ARG A 1 31 ? -5.092 23.927 -14.432 1.00 10.92 ? 31 ARG A CA 1 ATOM 226 C C . ARG A 1 31 ? -5.158 25.153 -13.510 1.00 12.11 ? 31 ARG A C 1 ATOM 227 O O . ARG A 1 31 ? -4.169 25.881 -13.361 1.00 11.67 ? 31 ARG A O 1 ATOM 228 C CB . ARG A 1 31 ? -6.086 24.046 -15.592 1.00 13.58 ? 31 ARG A CB 1 ATOM 229 C CG . ARG A 1 31 ? -5.410 23.845 -16.936 1.00 19.21 ? 31 ARG A CG 1 ATOM 230 C CD . ARG A 1 31 ? -6.166 22.970 -17.940 1.00 21.98 ? 31 ARG A CD 1 ATOM 231 N NE . ARG A 1 31 ? -5.324 22.784 -19.129 1.00 27.10 ? 31 ARG A NE 1 ATOM 232 C CZ . ARG A 1 31 ? -5.658 22.095 -20.218 1.00 29.09 ? 31 ARG A CZ 1 ATOM 233 N NH1 . ARG A 1 31 ? -6.842 21.502 -20.295 1.00 30.94 ? 31 ARG A NH1 1 ATOM 234 N NH2 . ARG A 1 31 ? -4.799 21.996 -21.234 1.00 29.56 ? 31 ARG A NH2 1 ATOM 235 N N . ARG A 1 32 ? -6.305 25.379 -12.877 1.00 11.19 ? 32 ARG A N 1 ATOM 236 C CA . ARG A 1 32 ? -6.428 26.529 -12.001 1.00 10.19 ? 32 ARG A CA 1 ATOM 237 C C . ARG A 1 32 ? -5.447 26.523 -10.803 1.00 8.35 ? 32 ARG A C 1 ATOM 238 O O . ARG A 1 32 ? -4.977 27.601 -10.413 1.00 7.75 ? 32 ARG A O 1 ATOM 239 C CB . ARG A 1 32 ? -7.859 26.652 -11.499 1.00 16.19 ? 32 ARG A CB 1 ATOM 240 C CG . ARG A 1 32 ? -8.572 27.884 -12.061 1.00 24.15 ? 32 ARG A CG 1 ATOM 241 C CD . ARG A 1 32 ? -10.032 27.919 -11.644 1.00 28.89 ? 32 ARG A CD 1 ATOM 242 N NE . ARG A 1 32 ? -10.904 28.391 -12.712 1.00 36.74 ? 32 ARG A NE 1 ATOM 243 C CZ . ARG A 1 32 ? -11.545 29.554 -12.689 1.00 39.30 ? 32 ARG A CZ 1 ATOM 244 N NH1 . ARG A 1 32 ? -11.406 30.374 -11.649 1.00 42.26 ? 32 ARG A NH1 1 ATOM 245 N NH2 . ARG A 1 32 ? -12.326 29.912 -13.689 1.00 42.71 ? 32 ARG A NH2 1 ATOM 246 N N . SER A 1 33 ? -5.164 25.379 -10.215 1.00 7.35 ? 33 SER A N 1 ATOM 247 C CA . SER A 1 33 ? -4.245 25.192 -9.105 1.00 7.80 ? 33 SER A CA 1 ATOM 248 C C . SER A 1 33 ? -3.291 24.075 -9.591 1.00 8.44 ? 33 SER A C 1 ATOM 249 O O . SER A 1 33 ? -3.684 22.903 -9.654 1.00 8.68 ? 33 SER A O 1 ATOM 250 C CB . SER A 1 33 ? -4.931 24.740 -7.810 1.00 6.92 ? 33 SER A CB 1 ATOM 251 O OG . SER A 1 33 ? -4.064 24.859 -6.689 1.00 6.24 ? 33 SER A OG 1 ATOM 252 N N . PRO A 1 34 ? -2.048 24.428 -9.950 1.00 6.92 ? 34 PRO A N 1 ATOM 253 C CA . PRO A 1 34 ? -1.015 23.440 -10.412 1.00 4.25 ? 34 PRO A CA 1 ATOM 254 C C . PRO A 1 34 ? -0.631 22.318 -9.436 1.00 5.47 ? 34 PRO A C 1 ATOM 255 O O . PRO A 1 34 ? -0.874 21.128 -9.681 1.00 7.28 ? 34 PRO A O 1 ATOM 256 C CB . PRO A 1 34 ? 0.147 24.283 -10.824 1.00 4.61 ? 34 PRO A CB 1 ATOM 257 C CG . PRO A 1 34 ? -0.542 25.446 -11.436 1.00 6.56 ? 34 PRO A CG 1 ATOM 258 C CD . PRO A 1 34 ? -1.929 25.574 -10.863 1.00 5.75 ? 34 PRO A CD 1 ATOM 259 N N . ALA A 1 35 ? -0.025 22.753 -8.319 1.00 4.12 ? 35 ALA A N 1 ATOM 260 C CA . ALA A 1 35 ? 0.458 21.850 -7.270 1.00 2.93 ? 35 ALA A CA 1 ATOM 261 C C . ALA A 1 35 ? -0.497 20.773 -6.855 1.00 2.00 ? 35 ALA A C 1 ATOM 262 O O . ALA A 1 35 ? -0.088 19.662 -6.516 1.00 2.00 ? 35 ALA A O 1 ATOM 263 C CB . ALA A 1 35 ? 0.904 22.668 -6.058 1.00 2.44 ? 35 ALA A CB 1 ATOM 264 N N . LEU A 1 36 ? -1.739 21.085 -6.863 1.00 2.04 ? 36 LEU A N 1 ATOM 265 C CA . LEU A 1 36 ? -2.714 20.146 -6.418 1.00 2.00 ? 36 LEU A CA 1 ATOM 266 C C . LEU A 1 36 ? -2.491 18.720 -6.826 1.00 2.50 ? 36 LEU A C 1 ATOM 267 O O . LEU A 1 36 ? -2.605 18.370 -7.989 1.00 2.00 ? 36 LEU A O 1 ATOM 268 C CB . LEU A 1 36 ? -4.055 20.611 -6.870 1.00 2.00 ? 36 LEU A CB 1 ATOM 269 C CG . LEU A 1 36 ? -5.122 20.439 -5.797 1.00 2.00 ? 36 LEU A CG 1 ATOM 270 C CD1 . LEU A 1 36 ? -4.637 21.026 -4.472 1.00 2.23 ? 36 LEU A CD1 1 ATOM 271 C CD2 . LEU A 1 36 ? -6.433 21.068 -6.245 1.00 3.51 ? 36 LEU A CD2 1 ATOM 272 N N . GLY A 1 37 ? -2.186 17.917 -5.844 1.00 3.30 ? 37 GLY A N 1 ATOM 273 C CA . GLY A 1 37 ? -1.972 16.522 -6.120 1.00 2.81 ? 37 GLY A CA 1 ATOM 274 C C . GLY A 1 37 ? -0.512 16.210 -6.386 1.00 2.38 ? 37 GLY A C 1 ATOM 275 O O . GLY A 1 37 ? -0.169 15.049 -6.663 1.00 2.37 ? 37 GLY A O 1 ATOM 276 N N . ALA A 1 38 ? 0.354 17.246 -6.306 1.00 2.00 ? 38 ALA A N 1 ATOM 277 C CA . ALA A 1 38 ? 1.780 17.030 -6.500 1.00 2.02 ? 38 ALA A CA 1 ATOM 278 C C . ALA A 1 38 ? 2.435 16.335 -5.326 1.00 2.00 ? 38 ALA A C 1 ATOM 279 O O . ALA A 1 38 ? 1.901 16.314 -4.217 1.00 2.15 ? 38 ALA A O 1 ATOM 280 C CB . ALA A 1 38 ? 2.486 18.352 -6.761 1.00 2.00 ? 38 ALA A CB 1 ATOM 281 N N . ALA A 1 39 ? 3.606 15.773 -5.592 1.00 2.00 ? 39 ALA A N 1 ATOM 282 C CA . ALA A 1 39 ? 4.370 15.086 -4.578 1.00 2.00 ? 39 ALA A CA 1 ATOM 283 C C . ALA A 1 39 ? 5.175 16.094 -3.788 1.00 2.30 ? 39 ALA A C 1 ATOM 284 O O . ALA A 1 39 ? 5.536 17.150 -4.294 1.00 2.82 ? 39 ALA A O 1 ATOM 285 C CB . ALA A 1 39 ? 5.288 14.097 -5.215 1.00 2.00 ? 39 ALA A CB 1 ATOM 286 N N . ASN A 1 40 ? 5.447 15.746 -2.537 1.00 3.33 ? 40 ASN A N 1 ATOM 287 C CA . ASN A 1 40 ? 6.247 16.569 -1.588 1.00 3.11 ? 40 ASN A CA 1 ATOM 288 C C . ASN A 1 40 ? 5.521 17.763 -1.059 1.00 4.16 ? 40 ASN A C 1 ATOM 289 O O . ASN A 1 40 ? 6.098 18.797 -0.734 1.00 4.91 ? 40 ASN A O 1 ATOM 290 C CB . ASN A 1 40 ? 7.557 17.013 -2.262 1.00 3.64 ? 40 ASN A CB 1 ATOM 291 C CG . ASN A 1 40 ? 8.493 15.832 -2.327 1.00 6.41 ? 40 ASN A CG 1 ATOM 292 O OD1 . ASN A 1 40 ? 8.983 15.372 -1.294 1.00 7.60 ? 40 ASN A OD1 1 ATOM 293 N ND2 . ASN A 1 40 ? 8.751 15.330 -3.533 1.00 7.16 ? 40 ASN A ND2 1 ATOM 294 N N . ARG A 1 41 ? 4.241 17.590 -0.976 1.00 3.79 ? 41 ARG A N 1 ATOM 295 C CA . ARG A 1 41 ? 3.352 18.616 -0.444 1.00 2.90 ? 41 ARG A CA 1 ATOM 296 C C . ARG A 1 41 ? 2.789 17.990 0.780 1.00 5.14 ? 41 ARG A C 1 ATOM 297 O O . ARG A 1 41 ? 2.933 16.776 0.922 1.00 6.31 ? 41 ARG A O 1 ATOM 298 C CB . ARG A 1 41 ? 2.153 18.909 -1.338 1.00 2.43 ? 41 ARG A CB 1 ATOM 299 C CG . ARG A 1 41 ? 2.507 19.501 -2.679 1.00 3.19 ? 41 ARG A CG 1 ATOM 300 C CD . ARG A 1 41 ? 3.635 20.487 -2.557 1.00 2.00 ? 41 ARG A CD 1 ATOM 301 N NE . ARG A 1 41 ? 3.995 20.978 -3.877 1.00 2.00 ? 41 ARG A NE 1 ATOM 302 C CZ . ARG A 1 41 ? 4.028 22.256 -4.229 1.00 2.02 ? 41 ARG A CZ 1 ATOM 303 N NH1 . ARG A 1 41 ? 3.715 23.189 -3.328 1.00 2.00 ? 41 ARG A NH1 1 ATOM 304 N NH2 . ARG A 1 41 ? 4.355 22.599 -5.463 1.00 3.90 ? 41 ARG A NH2 1 ATOM 305 N N . ALA A 1 42 ? 2.175 18.670 1.644 1.00 2.70 ? 42 ALA A N 1 ATOM 306 C CA . ALA A 1 42 ? 1.835 17.792 2.724 1.00 2.00 ? 42 ALA A CA 1 ATOM 307 C C . ALA A 1 42 ? 0.361 17.564 2.968 1.00 2.00 ? 42 ALA A C 1 ATOM 308 O O . ALA A 1 42 ? -0.378 18.417 3.424 1.00 2.00 ? 42 ALA A O 1 ATOM 309 C CB . ALA A 1 42 ? 2.469 18.307 4.010 1.00 3.46 ? 42 ALA A CB 1 ATOM 310 N N . LEU A 1 43 ? -0.006 16.350 2.623 1.00 2.12 ? 43 LEU A N 1 ATOM 311 C CA . LEU A 1 43 ? -1.279 15.642 2.853 1.00 2.00 ? 43 LEU A CA 1 ATOM 312 C C . LEU A 1 43 ? -2.552 16.394 3.140 1.00 2.50 ? 43 LEU A C 1 ATOM 313 O O . LEU A 1 43 ? -2.739 16.888 4.264 1.00 2.76 ? 43 LEU A O 1 ATOM 314 C CB . LEU A 1 43 ? -1.167 14.799 4.116 1.00 2.00 ? 43 LEU A CB 1 ATOM 315 C CG . LEU A 1 43 ? -0.379 13.497 4.091 1.00 2.00 ? 43 LEU A CG 1 ATOM 316 C CD1 . LEU A 1 43 ? 0.048 13.101 5.509 1.00 2.00 ? 43 LEU A CD1 1 ATOM 317 C CD2 . LEU A 1 43 ? -1.195 12.393 3.450 1.00 2.00 ? 43 LEU A CD2 1 ATOM 318 N N . ALA A 1 44 ? -3.447 16.509 2.175 1.00 2.02 ? 44 ALA A N 1 ATOM 319 C CA . ALA A 1 44 ? -4.862 16.896 2.654 1.00 2.37 ? 44 ALA A CA 1 ATOM 320 C C . ALA A 1 44 ? -5.412 16.492 4.064 1.00 4.50 ? 44 ALA A C 1 ATOM 321 O O . ALA A 1 44 ? -5.302 15.326 4.457 1.00 5.64 ? 44 ALA A O 1 ATOM 322 C CB . ALA A 1 44 ? -5.911 16.549 1.598 1.00 2.00 ? 44 ALA A CB 1 ATOM 323 N N . ARG A 1 45 ? -6.017 17.438 4.841 1.00 3.32 ? 45 ARG A N 1 ATOM 324 C CA . ARG A 1 45 ? -6.567 17.215 6.176 1.00 2.00 ? 45 ARG A CA 1 ATOM 325 C C . ARG A 1 45 ? -8.108 17.298 6.106 1.00 2.00 ? 45 ARG A C 1 ATOM 326 O O . ARG A 1 45 ? -8.630 18.269 5.563 1.00 3.41 ? 45 ARG A O 1 ATOM 327 C CB . ARG A 1 45 ? -6.072 18.244 7.213 1.00 2.00 ? 45 ARG A CB 1 ATOM 328 C CG . ARG A 1 45 ? -4.680 17.980 7.738 1.00 3.23 ? 45 ARG A CG 1 ATOM 329 C CD . ARG A 1 45 ? -4.633 17.165 9.029 1.00 3.32 ? 45 ARG A CD 1 ATOM 330 N NE . ARG A 1 45 ? -3.247 17.089 9.507 1.00 3.49 ? 45 ARG A NE 1 ATOM 331 C CZ . ARG A 1 45 ? -2.826 16.422 10.571 1.00 2.76 ? 45 ARG A CZ 1 ATOM 332 N NH1 . ARG A 1 45 ? -3.690 15.735 11.308 1.00 2.35 ? 45 ARG A NH1 1 ATOM 333 N NH2 . ARG A 1 45 ? -1.543 16.453 10.897 1.00 2.19 ? 45 ARG A NH2 1 ATOM 334 N N . TRP A 1 46 ? -8.827 16.300 6.628 1.00 2.49 ? 46 TRP A N 1 ATOM 335 C CA . TRP A 1 46 ? -10.275 16.377 6.561 1.00 3.28 ? 46 TRP A CA 1 ATOM 336 C C . TRP A 1 46 ? -10.859 16.828 7.902 1.00 3.80 ? 46 TRP A C 1 ATOM 337 O O . TRP A 1 46 ? -12.024 17.227 7.979 1.00 5.21 ? 46 TRP A O 1 ATOM 338 C CB . TRP A 1 46 ? -10.871 15.037 6.101 1.00 2.70 ? 46 TRP A CB 1 ATOM 339 C CG . TRP A 1 46 ? -10.529 14.686 4.665 1.00 2.10 ? 46 TRP A CG 1 ATOM 340 C CD1 . TRP A 1 46 ? -9.926 15.496 3.744 1.00 2.06 ? 46 TRP A CD1 1 ATOM 341 C CD2 . TRP A 1 46 ? -10.746 13.427 4.006 1.00 2.18 ? 46 TRP A CD2 1 ATOM 342 N NE1 . TRP A 1 46 ? -9.748 14.820 2.558 1.00 2.02 ? 46 TRP A NE1 1 ATOM 343 C CE2 . TRP A 1 46 ? -10.242 13.551 2.692 1.00 2.00 ? 46 TRP A CE2 1 ATOM 344 C CE3 . TRP A 1 46 ? -11.312 12.207 4.402 1.00 2.00 ? 46 TRP A CE3 1 ATOM 345 C CZ2 . TRP A 1 46 ? -10.285 12.504 1.773 1.00 2.00 ? 46 TRP A CZ2 1 ATOM 346 C CZ3 . TRP A 1 46 ? -11.354 11.163 3.483 1.00 2.00 ? 46 TRP A CZ3 1 ATOM 347 C CH2 . TRP A 1 46 ? -10.842 11.321 2.185 1.00 2.00 ? 46 TRP A CH2 1 ATOM 348 N N . LEU A 1 47 ? -10.038 16.745 8.949 1.00 2.70 ? 47 LEU A N 1 ATOM 349 C CA . LEU A 1 47 ? -10.444 17.153 10.282 1.00 2.00 ? 47 LEU A CA 1 ATOM 350 C C . LEU A 1 47 ? -9.270 17.866 10.966 1.00 2.81 ? 47 LEU A C 1 ATOM 351 O O . LEU A 1 47 ? -8.130 17.828 10.475 1.00 4.38 ? 47 LEU A O 1 ATOM 352 C CB . LEU A 1 47 ? -10.942 15.957 11.088 1.00 2.00 ? 47 LEU A CB 1 ATOM 353 C CG . LEU A 1 47 ? -12.374 15.524 10.792 1.00 2.00 ? 47 LEU A CG 1 ATOM 354 C CD1 . LEU A 1 47 ? -12.811 14.438 11.774 1.00 2.00 ? 47 LEU A CD1 1 ATOM 355 C CD2 . LEU A 1 47 ? -13.314 16.726 10.833 1.00 2.00 ? 47 LEU A CD2 1 ATOM 356 N N . PRO A 1 48 ? -9.568 18.532 12.102 1.00 2.00 ? 48 PRO A N 1 ATOM 357 C CA . PRO A 1 48 ? -8.538 19.339 12.859 1.00 2.00 ? 48 PRO A CA 1 ATOM 358 C C . PRO A 1 48 ? -7.374 18.568 13.315 1.00 2.00 ? 48 PRO A C 1 ATOM 359 O O . PRO A 1 48 ? -7.561 17.417 13.694 1.00 2.00 ? 48 PRO A O 1 ATOM 360 C CB . PRO A 1 48 ? -9.293 19.966 13.989 1.00 3.36 ? 48 PRO A CB 1 ATOM 361 C CG . PRO A 1 48 ? -10.559 20.313 13.291 1.00 4.25 ? 48 PRO A CG 1 ATOM 362 C CD . PRO A 1 48 ? -10.740 19.393 12.123 1.00 3.14 ? 48 PRO A CD 1 ATOM 363 N N . ALA A 1 49 ? -6.172 19.071 13.302 1.00 2.08 ? 49 ALA A N 1 ATOM 364 C CA . ALA A 1 49 ? -5.180 18.203 13.895 1.00 2.00 ? 49 ALA A CA 1 ATOM 365 C C . ALA A 1 49 ? -5.415 18.157 15.411 1.00 2.49 ? 49 ALA A C 1 ATOM 366 O O . ALA A 1 49 ? -5.618 19.188 16.050 1.00 2.43 ? 49 ALA A O 1 ATOM 367 C CB . ALA A 1 49 ? -3.772 18.687 13.616 1.00 2.00 ? 49 ALA A CB 1 ATOM 368 N N . GLU A 1 50 ? -5.352 16.949 15.955 1.00 3.40 ? 50 GLU A N 1 ATOM 369 C CA . GLU A 1 50 ? -5.408 16.775 17.381 1.00 3.51 ? 50 GLU A CA 1 ATOM 370 C C . GLU A 1 50 ? -3.987 16.409 17.802 1.00 4.16 ? 50 GLU A C 1 ATOM 371 O O . GLU A 1 50 ? -3.418 15.419 17.346 1.00 4.22 ? 50 GLU A O 1 ATOM 372 C CB . GLU A 1 50 ? -6.529 15.803 17.751 1.00 2.00 ? 50 GLU A CB 1 ATOM 373 C CG . GLU A 1 50 ? -7.895 16.318 17.353 1.00 2.92 ? 50 GLU A CG 1 ATOM 374 C CD . GLU A 1 50 ? -9.061 15.681 18.101 1.00 3.62 ? 50 GLU A CD 1 ATOM 375 O OE1 . GLU A 1 50 ? -8.831 14.688 18.819 1.00 2.17 ? 50 GLU A OE1 1 ATOM 376 O OE2 . GLU A 1 50 ? -10.184 16.190 17.963 1.00 2.61 ? 50 GLU A OE2 1 ATOM 377 N N . TYR A 1 51 ? -3.456 17.252 18.650 1.00 5.29 ? 51 TYR A N 1 ATOM 378 C CA . TYR A 1 51 ? -2.155 17.044 19.271 1.00 5.38 ? 51 TYR A CA 1 ATOM 379 C C . TYR A 1 51 ? -2.346 17.389 20.739 1.00 5.94 ? 51 TYR A C 1 ATOM 380 O O . TYR A 1 51 ? -3.324 18.038 21.108 1.00 4.14 ? 51 TYR A O 1 ATOM 381 C CB . TYR A 1 51 ? -1.055 17.921 18.695 1.00 5.81 ? 51 TYR A CB 1 ATOM 382 C CG . TYR A 1 51 ? -0.518 17.478 17.353 1.00 6.13 ? 51 TYR A CG 1 ATOM 383 C CD1 . TYR A 1 51 ? 0.123 16.258 17.204 1.00 6.83 ? 51 TYR A CD1 1 ATOM 384 C CD2 . TYR A 1 51 ? -0.658 18.310 16.238 1.00 6.90 ? 51 TYR A CD2 1 ATOM 385 C CE1 . TYR A 1 51 ? 0.623 15.878 15.971 1.00 8.26 ? 51 TYR A CE1 1 ATOM 386 C CE2 . TYR A 1 51 ? -0.134 17.943 15.003 1.00 6.20 ? 51 TYR A CE2 1 ATOM 387 C CZ . TYR A 1 51 ? 0.507 16.729 14.876 1.00 6.93 ? 51 TYR A CZ 1 ATOM 388 O OH . TYR A 1 51 ? 1.047 16.370 13.664 1.00 8.77 ? 51 TYR A OH 1 ATOM 389 N N . GLU A 1 52 ? -1.395 16.962 21.564 1.00 8.39 ? 52 GLU A N 1 ATOM 390 C CA . GLU A 1 52 ? -1.441 17.191 23.005 1.00 10.11 ? 52 GLU A CA 1 ATOM 391 C C . GLU A 1 52 ? -1.247 18.658 23.387 1.00 10.30 ? 52 GLU A C 1 ATOM 392 O O . GLU A 1 52 ? -1.859 19.133 24.350 1.00 11.33 ? 52 GLU A O 1 ATOM 393 C CB . GLU A 1 52 ? -0.382 16.339 23.697 1.00 12.34 ? 52 GLU A CB 1 ATOM 394 C CG . GLU A 1 52 ? -0.506 16.289 25.201 1.00 16.35 ? 52 GLU A CG 1 ATOM 395 C CD . GLU A 1 52 ? 0.734 15.717 25.849 1.00 18.30 ? 52 GLU A CD 1 ATOM 396 O OE1 . GLU A 1 52 ? 1.705 16.483 26.050 1.00 18.90 ? 52 GLU A OE1 1 ATOM 397 O OE2 . GLU A 1 52 ? 0.741 14.500 26.140 1.00 20.18 ? 52 GLU A OE2 1 ATOM 398 N N . ASP A 1 53 ? -0.386 19.364 22.654 1.00 9.17 ? 53 ASP A N 1 ATOM 399 C CA . ASP A 1 53 ? -0.152 20.785 22.912 1.00 8.05 ? 53 ASP A CA 1 ATOM 400 C C . ASP A 1 53 ? -0.804 21.566 21.780 1.00 6.61 ? 53 ASP A C 1 ATOM 401 O O . ASP A 1 53 ? -0.393 22.683 21.447 1.00 5.14 ? 53 ASP A O 1 ATOM 402 C CB . ASP A 1 53 ? 1.350 21.102 22.986 1.00 9.16 ? 53 ASP A CB 1 ATOM 403 C CG . ASP A 1 53 ? 2.021 21.136 21.617 1.00 11.09 ? 53 ASP A CG 1 ATOM 404 O OD1 . ASP A 1 53 ? 1.516 20.474 20.689 1.00 12.65 ? 53 ASP A OD1 1 ATOM 405 O OD2 . ASP A 1 53 ? 3.036 21.840 21.470 1.00 11.50 ? 53 ASP A OD2 1 ATOM 406 N N . GLY A 1 54 ? -1.831 20.982 21.195 1.00 6.71 ? 54 GLY A N 1 ATOM 407 C CA . GLY A 1 54 ? -2.594 21.606 20.139 1.00 7.60 ? 54 GLY A CA 1 ATOM 408 C C . GLY A 1 54 ? -1.783 21.969 18.906 1.00 7.45 ? 54 GLY A C 1 ATOM 409 O O . GLY A 1 54 ? -2.293 22.641 18.015 1.00 8.92 ? 54 GLY A O 1 ATOM 410 N N . LEU A 1 55 ? -0.533 21.523 18.833 1.00 7.65 ? 55 LEU A N 1 ATOM 411 C CA . LEU A 1 55 ? 0.313 21.853 17.686 1.00 7.00 ? 55 LEU A CA 1 ATOM 412 C C . LEU A 1 55 ? 1.228 20.734 17.193 1.00 6.58 ? 55 LEU A C 1 ATOM 413 O O . LEU A 1 55 ? 1.305 20.502 15.987 1.00 7.48 ? 55 LEU A O 1 ATOM 414 C CB . LEU A 1 55 ? 1.175 23.076 18.037 1.00 5.38 ? 55 LEU A CB 1 ATOM 415 C CG . LEU A 1 55 ? 0.444 24.382 18.291 1.00 3.28 ? 55 LEU A CG 1 ATOM 416 C CD1 . LEU A 1 55 ? 1.369 25.407 18.923 1.00 2.00 ? 55 LEU A CD1 1 ATOM 417 C CD2 . LEU A 1 55 ? -0.138 24.920 16.997 1.00 3.31 ? 55 LEU A CD2 1 ATOM 418 N N . ALA A 1 56 ? 1.902 20.016 18.095 1.00 5.51 ? 56 ALA A N 1 ATOM 419 C CA . ALA A 1 56 ? 2.818 18.993 17.600 1.00 4.55 ? 56 ALA A CA 1 ATOM 420 C C . ALA A 1 56 ? 3.256 17.850 18.548 1.00 4.97 ? 56 ALA A C 1 ATOM 421 O O . ALA A 1 56 ? 3.806 16.864 18.051 1.00 7.43 ? 56 ALA A O 1 ATOM 422 C CB . ALA A 1 56 ? 4.047 19.681 17.051 1.00 4.62 ? 56 ALA A CB 1 ATOM 423 N N . VAL A 1 57 ? 3.036 17.895 19.859 1.00 5.01 ? 57 VAL A N 1 ATOM 424 C CA . VAL A 1 57 ? 3.474 16.722 20.633 1.00 4.57 ? 57 VAL A CA 1 ATOM 425 C C . VAL A 1 57 ? 2.370 15.667 20.643 1.00 3.04 ? 57 VAL A C 1 ATOM 426 O O . VAL A 1 57 ? 1.242 15.899 21.051 1.00 3.26 ? 57 VAL A O 1 ATOM 427 C CB . VAL A 1 57 ? 3.934 17.052 22.084 1.00 4.57 ? 57 VAL A CB 1 ATOM 428 C CG1 . VAL A 1 57 ? 5.077 18.044 22.076 1.00 4.75 ? 57 VAL A CG1 1 ATOM 429 C CG2 . VAL A 1 57 ? 2.778 17.598 22.917 1.00 5.87 ? 57 VAL A CG2 1 ATOM 430 N N . PRO A 1 58 ? 2.781 14.456 20.185 1.00 3.57 ? 58 PRO A N 1 ATOM 431 C CA . PRO A 1 58 ? 1.872 13.308 20.138 1.00 3.62 ? 58 PRO A CA 1 ATOM 432 C C . PRO A 1 58 ? 1.069 13.003 21.390 1.00 2.46 ? 58 PRO A C 1 ATOM 433 O O . PRO A 1 58 ? 1.610 13.179 22.479 1.00 4.20 ? 58 PRO A O 1 ATOM 434 C CB . PRO A 1 58 ? 2.761 12.215 19.583 1.00 4.18 ? 58 PRO A CB 1 ATOM 435 C CG . PRO A 1 58 ? 3.572 12.971 18.577 1.00 4.02 ? 58 PRO A CG 1 ATOM 436 C CD . PRO A 1 58 ? 3.665 14.397 19.010 1.00 2.47 ? 58 PRO A CD 1 ATOM 437 N N . PHE A 1 59 ? -0.181 12.554 21.306 1.00 2.08 ? 59 PHE A N 1 ATOM 438 C CA . PHE A 1 59 ? -0.857 12.195 22.546 1.00 3.79 ? 59 PHE A CA 1 ATOM 439 C C . PHE A 1 59 ? -0.225 10.951 23.135 1.00 4.84 ? 59 PHE A C 1 ATOM 440 O O . PHE A 1 59 ? -0.274 9.873 22.547 1.00 6.39 ? 59 PHE A O 1 ATOM 441 C CB . PHE A 1 59 ? -2.349 11.938 22.334 1.00 2.18 ? 59 PHE A CB 1 ATOM 442 C CG . PHE A 1 59 ? -3.202 13.140 22.570 1.00 2.00 ? 59 PHE A CG 1 ATOM 443 C CD1 . PHE A 1 59 ? -3.843 13.765 21.519 1.00 2.10 ? 59 PHE A CD1 1 ATOM 444 C CD2 . PHE A 1 59 ? -3.342 13.668 23.845 1.00 2.82 ? 59 PHE A CD2 1 ATOM 445 C CE1 . PHE A 1 59 ? -4.611 14.900 21.734 1.00 2.02 ? 59 PHE A CE1 1 ATOM 446 C CE2 . PHE A 1 59 ? -4.111 14.807 24.066 1.00 2.00 ? 59 PHE A CE2 1 ATOM 447 C CZ . PHE A 1 59 ? -4.743 15.420 23.010 1.00 2.00 ? 59 PHE A CZ 1 ATOM 448 N N . GLY A 1 60 ? 0.377 11.100 24.303 1.00 6.07 ? 60 GLY A N 1 ATOM 449 C CA . GLY A 1 60 ? 0.987 9.955 24.935 1.00 7.23 ? 60 GLY A CA 1 ATOM 450 C C . GLY A 1 60 ? 2.483 10.085 24.981 1.00 8.66 ? 60 GLY A C 1 ATOM 451 O O . GLY A 1 60 ? 3.181 9.087 25.126 1.00 11.83 ? 60 GLY A O 1 ATOM 452 N N . TRP A 1 61 ? 2.977 11.312 24.861 1.00 8.55 ? 61 TRP A N 1 ATOM 453 C CA . TRP A 1 61 ? 4.410 11.533 24.898 1.00 10.45 ? 61 TRP A CA 1 ATOM 454 C C . TRP A 1 61 ? 4.815 12.239 26.166 1.00 11.26 ? 61 TRP A C 1 ATOM 455 O O . TRP A 1 61 ? 5.871 11.990 26.743 1.00 10.92 ? 61 TRP A O 1 ATOM 456 C CB . TRP A 1 61 ? 4.846 12.349 23.687 1.00 10.68 ? 61 TRP A CB 1 ATOM 457 C CG . TRP A 1 61 ? 5.931 13.393 23.908 1.00 10.21 ? 61 TRP A CG 1 ATOM 458 C CD1 . TRP A 1 61 ? 5.949 14.424 24.802 1.00 10.84 ? 61 TRP A CD1 1 ATOM 459 C CD2 . TRP A 1 61 ? 7.145 13.500 23.150 1.00 9.73 ? 61 TRP A CD2 1 ATOM 460 N NE1 . TRP A 1 61 ? 7.090 15.169 24.646 1.00 11.92 ? 61 TRP A NE1 1 ATOM 461 C CE2 . TRP A 1 61 ? 7.843 14.627 23.639 1.00 10.14 ? 61 TRP A CE2 1 ATOM 462 C CE3 . TRP A 1 61 ? 7.707 12.757 22.105 1.00 8.85 ? 61 TRP A CE3 1 ATOM 463 C CZ2 . TRP A 1 61 ? 9.075 15.033 23.119 1.00 10.02 ? 61 TRP A CZ2 1 ATOM 464 C CZ3 . TRP A 1 61 ? 8.934 13.160 21.586 1.00 10.35 ? 61 TRP A CZ3 1 ATOM 465 C CH2 . TRP A 1 61 ? 9.604 14.291 22.096 1.00 10.58 ? 61 TRP A CH2 1 ATOM 466 N N . THR A 1 62 ? 3.976 13.163 26.592 1.00 13.44 ? 62 THR A N 1 ATOM 467 C CA . THR A 1 62 ? 4.221 13.794 27.847 1.00 16.82 ? 62 THR A CA 1 ATOM 468 C C . THR A 1 62 ? 3.569 12.775 28.802 1.00 18.07 ? 62 THR A C 1 ATOM 469 O O . THR A 1 62 ? 2.369 12.500 28.703 1.00 15.62 ? 62 THR A O 1 ATOM 470 C CB . THR A 1 62 ? 3.666 15.239 27.936 1.00 17.26 ? 62 THR A CB 1 ATOM 471 O OG1 . THR A 1 62 ? 4.338 16.048 26.967 1.00 19.06 ? 62 THR A OG1 1 ATOM 472 C CG2 . THR A 1 62 ? 3.874 15.826 29.325 1.00 18.31 ? 62 THR A CG2 1 ATOM 473 N N . GLN A 1 63 ? 4.348 12.205 29.734 1.00 21.33 ? 63 GLN A N 1 ATOM 474 C CA . GLN A 1 63 ? 3.938 11.174 30.708 1.00 24.65 ? 63 GLN A CA 1 ATOM 475 C C . GLN A 1 63 ? 2.987 11.631 31.807 1.00 26.23 ? 63 GLN A C 1 ATOM 476 O O . GLN A 1 63 ? 2.982 11.025 32.875 1.00 26.67 ? 63 GLN A O 1 ATOM 477 C CB . GLN A 1 63 ? 5.200 10.596 31.388 1.00 27.90 ? 63 GLN A CB 1 ATOM 478 C CG . GLN A 1 63 ? 6.229 9.988 30.439 1.00 32.62 ? 63 GLN A CG 1 ATOM 479 C CD . GLN A 1 63 ? 5.906 8.556 30.046 1.00 34.49 ? 63 GLN A CD 1 ATOM 480 O OE1 . GLN A 1 63 ? 4.871 8.294 29.433 1.00 36.07 ? 63 GLN A OE1 1 ATOM 481 N NE2 . GLN A 1 63 ? 6.649 7.497 30.283 1.00 34.82 ? 63 GLN A NE2 1 ATOM 482 N N . ARG A 1 64 ? 2.185 12.666 31.582 1.00 27.48 ? 64 ARG A N 1 ATOM 483 C CA . ARG A 1 64 ? 1.272 13.077 32.663 1.00 28.72 ? 64 ARG A CA 1 ATOM 484 C C . ARG A 1 64 ? 0.032 13.873 32.197 1.00 27.27 ? 64 ARG A C 1 ATOM 485 O O . ARG A 1 64 ? -0.955 13.946 32.938 1.00 25.98 ? 64 ARG A O 1 ATOM 486 C CB . ARG A 1 64 ? 2.029 13.859 33.723 1.00 32.93 ? 64 ARG A CB 1 ATOM 487 C CG . ARG A 1 64 ? 2.890 15.001 33.194 1.00 38.70 ? 64 ARG A CG 1 ATOM 488 C CD . ARG A 1 64 ? 2.080 16.254 32.972 1.00 43.37 ? 64 ARG A CD 1 ATOM 489 N NE . ARG A 1 64 ? 2.886 17.477 32.980 1.00 47.46 ? 64 ARG A NE 1 ATOM 490 C CZ . ARG A 1 64 ? 2.401 18.696 32.754 1.00 48.58 ? 64 ARG A CZ 1 ATOM 491 N NH1 . ARG A 1 64 ? 1.102 18.869 32.526 1.00 50.17 ? 64 ARG A NH1 1 ATOM 492 N NH2 . ARG A 1 64 ? 3.214 19.746 32.758 1.00 49.20 ? 64 ARG A NH2 1 ATOM 493 N N . LYS A 1 65 ? 0.079 14.472 31.009 1.00 26.30 ? 65 LYS A N 1 ATOM 494 C CA . LYS A 1 65 ? -1.116 15.131 30.454 1.00 24.25 ? 65 LYS A CA 1 ATOM 495 C C . LYS A 1 65 ? -2.016 13.993 29.965 1.00 20.83 ? 65 LYS A C 1 ATOM 496 O O . LYS A 1 65 ? -1.527 12.889 29.724 1.00 21.03 ? 65 LYS A O 1 ATOM 497 C CB . LYS A 1 65 ? -0.761 16.066 29.272 1.00 27.21 ? 65 LYS A CB 1 ATOM 498 C CG . LYS A 1 65 ? 0.184 17.225 29.603 1.00 31.37 ? 65 LYS A CG 1 ATOM 499 C CD . LYS A 1 65 ? 0.456 18.061 28.361 1.00 35.60 ? 65 LYS A CD 1 ATOM 500 C CE . LYS A 1 65 ? 1.358 19.255 28.651 1.00 37.79 ? 65 LYS A CE 1 ATOM 501 N NZ . LYS A 1 65 ? 1.364 20.241 27.530 1.00 39.60 ? 65 LYS A NZ 1 ATOM 502 N N . THR A 1 66 ? -3.311 14.235 29.815 1.00 15.98 ? 66 THR A N 1 ATOM 503 C CA . THR A 1 66 ? -4.195 13.161 29.371 1.00 12.62 ? 66 THR A CA 1 ATOM 504 C C . THR A 1 66 ? -4.842 13.489 28.048 1.00 11.35 ? 66 THR A C 1 ATOM 505 O O . THR A 1 66 ? -4.533 14.499 27.415 1.00 12.00 ? 66 THR A O 1 ATOM 506 C CB . THR A 1 66 ? -5.307 12.893 30.433 1.00 12.63 ? 66 THR A CB 1 ATOM 507 O OG1 . THR A 1 66 ? -6.356 13.865 30.280 1.00 11.79 ? 66 THR A OG1 1 ATOM 508 C CG2 . THR A 1 66 ? -4.725 12.963 31.836 1.00 11.70 ? 66 THR A CG2 1 ATOM 509 N N . ARG A 1 67 ? -5.764 12.652 27.670 1.00 9.02 ? 67 ARG A N 1 ATOM 510 C CA . ARG A 1 67 ? -6.603 12.867 26.536 1.00 6.88 ? 67 ARG A CA 1 ATOM 511 C C . ARG A 1 67 ? -7.976 12.797 27.148 1.00 6.71 ? 67 ARG A C 1 ATOM 512 O O . ARG A 1 67 ? -8.297 11.778 27.759 1.00 5.59 ? 67 ARG A O 1 ATOM 513 C CB . ARG A 1 67 ? -6.409 11.786 25.456 1.00 6.45 ? 67 ARG A CB 1 ATOM 514 C CG . ARG A 1 67 ? -6.974 12.139 24.103 1.00 5.17 ? 67 ARG A CG 1 ATOM 515 C CD . ARG A 1 67 ? -6.846 10.943 23.163 1.00 5.27 ? 67 ARG A CD 1 ATOM 516 N NE . ARG A 1 67 ? -7.431 11.172 21.848 1.00 4.49 ? 67 ARG A NE 1 ATOM 517 C CZ . ARG A 1 67 ? -6.723 11.308 20.729 1.00 3.93 ? 67 ARG A CZ 1 ATOM 518 N NH1 . ARG A 1 67 ? -5.397 11.236 20.756 1.00 2.00 ? 67 ARG A NH1 1 ATOM 519 N NH2 . ARG A 1 67 ? -7.347 11.512 19.576 1.00 4.46 ? 67 ARG A NH2 1 ATOM 520 N N . ASN A 1 68 ? -8.798 13.800 27.019 1.00 5.74 ? 68 ASN A N 1 ATOM 521 C CA . ASN A 1 68 ? -10.146 13.675 27.568 1.00 5.23 ? 68 ASN A CA 1 ATOM 522 C C . ASN A 1 68 ? -10.247 13.164 29.013 1.00 4.73 ? 68 ASN A C 1 ATOM 523 O O . ASN A 1 68 ? -11.266 12.614 29.435 1.00 3.85 ? 68 ASN A O 1 ATOM 524 C CB . ASN A 1 68 ? -10.951 12.738 26.646 1.00 5.41 ? 68 ASN A CB 1 ATOM 525 C CG . ASN A 1 68 ? -11.035 13.287 25.248 1.00 6.19 ? 68 ASN A CG 1 ATOM 526 O OD1 . ASN A 1 68 ? -11.426 14.440 25.049 1.00 5.77 ? 68 ASN A OD1 1 ATOM 527 N ND2 . ASN A 1 68 ? -10.666 12.471 24.265 1.00 7.00 ? 68 ASN A ND2 1 ATOM 528 N N . GLY A 1 69 ? -9.180 13.358 29.769 1.00 4.49 ? 69 GLY A N 1 ATOM 529 C CA . GLY A 1 69 ? -9.173 13.001 31.164 1.00 6.58 ? 69 GLY A CA 1 ATOM 530 C C . GLY A 1 69 ? -8.632 11.616 31.442 1.00 8.07 ? 69 GLY A C 1 ATOM 531 O O . GLY A 1 69 ? -8.718 11.126 32.573 1.00 8.15 ? 69 GLY A O 1 ATOM 532 N N . PHE A 1 70 ? -8.067 10.978 30.424 1.00 8.73 ? 70 PHE A N 1 ATOM 533 C CA . PHE A 1 70 ? -7.536 9.639 30.607 1.00 8.85 ? 70 PHE A CA 1 ATOM 534 C C . PHE A 1 70 ? -6.168 9.437 29.988 1.00 9.00 ? 70 PHE A C 1 ATOM 535 O O . PHE A 1 70 ? -5.839 10.032 28.966 1.00 9.14 ? 70 PHE A O 1 ATOM 536 C CB . PHE A 1 70 ? -8.517 8.609 30.045 1.00 9.82 ? 70 PHE A CB 1 ATOM 537 C CG . PHE A 1 70 ? -9.826 8.555 30.784 1.00 11.16 ? 70 PHE A CG 1 ATOM 538 C CD1 . PHE A 1 70 ? -11.032 8.693 30.097 1.00 11.84 ? 70 PHE A CD1 1 ATOM 539 C CD2 . PHE A 1 70 ? -9.854 8.369 32.167 1.00 11.56 ? 70 PHE A CD2 1 ATOM 540 C CE1 . PHE A 1 70 ? -12.250 8.650 30.770 1.00 12.46 ? 70 PHE A CE1 1 ATOM 541 C CE2 . PHE A 1 70 ? -11.059 8.323 32.855 1.00 12.59 ? 70 PHE A CE2 1 ATOM 542 C CZ . PHE A 1 70 ? -12.266 8.464 32.153 1.00 14.35 ? 70 PHE A CZ 1 ATOM 543 N N . ARG A 1 71 ? -5.379 8.589 30.637 1.00 9.24 ? 71 ARG A N 1 ATOM 544 C CA . ARG A 1 71 ? -4.033 8.201 30.173 1.00 9.41 ? 71 ARG A CA 1 ATOM 545 C C . ARG A 1 71 ? -4.120 7.389 28.879 1.00 7.09 ? 71 ARG A C 1 ATOM 546 O O . ARG A 1 71 ? -4.960 6.498 28.774 1.00 6.87 ? 71 ARG A O 1 ATOM 547 C CB . ARG A 1 71 ? -3.359 7.327 31.248 1.00 14.60 ? 71 ARG A CB 1 ATOM 548 C CG . ARG A 1 71 ? -2.043 7.860 31.763 1.00 22.08 ? 71 ARG A CG 1 ATOM 549 C CD . ARG A 1 71 ? -2.102 8.103 33.251 1.00 26.54 ? 71 ARG A CD 1 ATOM 550 N NE . ARG A 1 71 ? -1.466 9.371 33.590 1.00 31.37 ? 71 ARG A NE 1 ATOM 551 C CZ . ARG A 1 71 ? -0.157 9.551 33.723 1.00 33.03 ? 71 ARG A CZ 1 ATOM 552 N NH1 . ARG A 1 71 ? 0.682 8.536 33.550 1.00 35.49 ? 71 ARG A NH1 1 ATOM 553 N NH2 . ARG A 1 71 ? 0.311 10.751 34.033 1.00 34.47 ? 71 ARG A NH2 1 ATOM 554 N N . VAL A 1 72 ? -3.271 7.667 27.861 1.00 4.12 ? 72 VAL A N 1 ATOM 555 C CA . VAL A 1 72 ? -3.344 6.894 26.580 1.00 3.95 ? 72 VAL A CA 1 ATOM 556 C C . VAL A 1 72 ? -2.477 5.630 26.672 1.00 3.18 ? 72 VAL A C 1 ATOM 557 O O . VAL A 1 72 ? -1.338 5.661 27.145 1.00 2.00 ? 72 VAL A O 1 ATOM 558 C CB . VAL A 1 72 ? -2.928 7.708 25.365 1.00 2.00 ? 72 VAL A CB 1 ATOM 559 C CG1 . VAL A 1 72 ? -3.145 9.200 25.617 1.00 2.00 ? 72 VAL A CG1 1 ATOM 560 C CG2 . VAL A 1 72 ? -1.475 7.442 24.996 1.00 3.52 ? 72 VAL A CG2 1 ATOM 561 N N . PRO A 1 73 ? -3.030 4.521 26.203 1.00 2.00 ? 73 PRO A N 1 ATOM 562 C CA . PRO A 1 73 ? -2.346 3.192 26.307 1.00 2.00 ? 73 PRO A CA 1 ATOM 563 C C . PRO A 1 73 ? -1.007 3.073 25.648 1.00 2.53 ? 73 PRO A C 1 ATOM 564 O O . PRO A 1 73 ? -0.808 3.627 24.567 1.00 2.00 ? 73 PRO A O 1 ATOM 565 C CB . PRO A 1 73 ? -3.369 2.224 25.758 1.00 2.98 ? 73 PRO A CB 1 ATOM 566 C CG . PRO A 1 73 ? -4.612 2.793 26.333 1.00 2.97 ? 73 PRO A CG 1 ATOM 567 C CD . PRO A 1 73 ? -4.404 4.244 26.607 1.00 2.41 ? 73 PRO A CD 1 ATOM 568 N N . LEU A 1 74 ? -0.069 2.385 26.244 1.00 4.87 ? 74 LEU A N 1 ATOM 569 C CA . LEU A 1 74 ? 1.167 2.276 25.519 1.00 3.64 ? 74 LEU A CA 1 ATOM 570 C C . LEU A 1 74 ? 0.930 1.665 24.129 1.00 2.41 ? 74 LEU A C 1 ATOM 571 O O . LEU A 1 74 ? 0.114 0.756 23.978 1.00 2.00 ? 74 LEU A O 1 ATOM 572 C CB . LEU A 1 74 ? 2.184 1.448 26.274 1.00 3.92 ? 74 LEU A CB 1 ATOM 573 C CG . LEU A 1 74 ? 2.560 1.984 27.634 1.00 3.95 ? 74 LEU A CG 1 ATOM 574 C CD1 . LEU A 1 74 ? 3.640 1.125 28.285 1.00 4.67 ? 74 LEU A CD1 1 ATOM 575 C CD2 . LEU A 1 74 ? 3.030 3.424 27.539 1.00 4.39 ? 74 LEU A CD2 1 ATOM 576 N N . ALA A 1 75 ? 1.645 2.171 23.134 1.00 2.19 ? 75 ALA A N 1 ATOM 577 C CA . ALA A 1 75 ? 1.481 1.657 21.786 1.00 2.56 ? 75 ALA A CA 1 ATOM 578 C C . ALA A 1 75 ? 1.510 0.131 21.815 1.00 2.00 ? 75 ALA A C 1 ATOM 579 O O . ALA A 1 75 ? 0.535 -0.516 21.411 1.00 2.00 ? 75 ALA A O 1 ATOM 580 C CB . ALA A 1 75 ? 2.575 2.206 20.878 1.00 2.00 ? 75 ALA A CB 1 ATOM 581 N N . ARG A 1 76 ? 2.617 -0.430 22.302 1.00 2.02 ? 76 ARG A N 1 ATOM 582 C CA . ARG A 1 76 ? 2.812 -1.882 22.388 1.00 3.45 ? 76 ARG A CA 1 ATOM 583 C C . ARG A 1 76 ? 1.782 -2.646 23.227 1.00 4.52 ? 76 ARG A C 1 ATOM 584 O O . ARG A 1 76 ? 1.381 -3.754 22.872 1.00 4.18 ? 76 ARG A O 1 ATOM 585 C CB . ARG A 1 76 ? 4.214 -2.183 22.899 1.00 2.08 ? 76 ARG A CB 1 ATOM 586 C CG . ARG A 1 76 ? 4.444 -3.643 23.306 1.00 2.00 ? 76 ARG A CG 1 ATOM 587 C CD . ARG A 1 76 ? 4.623 -4.561 22.090 1.00 5.01 ? 76 ARG A CD 1 ATOM 588 N NE . ARG A 1 76 ? 5.307 -5.816 22.435 1.00 5.14 ? 76 ARG A NE 1 ATOM 589 C CZ . ARG A 1 76 ? 5.613 -6.783 21.568 1.00 3.88 ? 76 ARG A CZ 1 ATOM 590 N NH1 . ARG A 1 76 ? 5.304 -6.671 20.282 1.00 2.07 ? 76 ARG A NH1 1 ATOM 591 N NH2 . ARG A 1 76 ? 6.239 -7.868 21.990 1.00 4.48 ? 76 ARG A NH2 1 ATOM 592 N N . GLU A 1 77 ? 1.356 -2.075 24.342 1.00 3.89 ? 77 GLU A N 1 ATOM 593 C CA . GLU A 1 77 ? 0.402 -2.771 25.180 1.00 4.30 ? 77 GLU A CA 1 ATOM 594 C C . GLU A 1 77 ? -0.867 -3.182 24.418 1.00 3.92 ? 77 GLU A C 1 ATOM 595 O O . GLU A 1 77 ? -1.390 -4.271 24.658 1.00 2.00 ? 77 GLU A O 1 ATOM 596 C CB . GLU A 1 77 ? 0.077 -1.905 26.400 1.00 9.19 ? 77 GLU A CB 1 ATOM 597 C CG . GLU A 1 77 ? -0.954 -2.492 27.353 1.00 16.66 ? 77 GLU A CG 1 ATOM 598 C CD . GLU A 1 77 ? -0.982 -1.767 28.702 1.00 21.05 ? 77 GLU A CD 1 ATOM 599 O OE1 . GLU A 1 77 ? -0.732 -0.541 28.737 1.00 24.10 ? 77 GLU A OE1 1 ATOM 600 O OE2 . GLU A 1 77 ? -1.268 -2.423 29.725 1.00 22.24 ? 77 GLU A OE2 1 ATOM 601 N N . VAL A 1 78 ? -1.349 -2.330 23.518 1.00 3.24 ? 78 VAL A N 1 ATOM 602 C CA . VAL A 1 78 ? -2.559 -2.640 22.748 1.00 2.86 ? 78 VAL A CA 1 ATOM 603 C C . VAL A 1 78 ? -2.314 -3.873 21.891 1.00 4.13 ? 78 VAL A C 1 ATOM 604 O O . VAL A 1 78 ? -3.149 -4.778 21.795 1.00 4.63 ? 78 VAL A O 1 ATOM 605 C CB . VAL A 1 78 ? -2.953 -1.451 21.837 1.00 2.00 ? 78 VAL A CB 1 ATOM 606 C CG1 . VAL A 1 78 ? -4.019 -1.868 20.830 1.00 2.00 ? 78 VAL A CG1 1 ATOM 607 C CG2 . VAL A 1 78 ? -3.463 -0.281 22.662 1.00 2.00 ? 78 VAL A CG2 1 ATOM 608 N N . SER A 1 79 ? -1.141 -3.888 21.279 1.00 2.82 ? 79 SER A N 1 ATOM 609 C CA . SER A 1 79 ? -0.711 -4.971 20.423 1.00 3.06 ? 79 SER A CA 1 ATOM 610 C C . SER A 1 79 ? -0.738 -6.314 21.188 1.00 5.57 ? 79 SER A C 1 ATOM 611 O O . SER A 1 79 ? -1.275 -7.306 20.683 1.00 6.23 ? 79 SER A O 1 ATOM 612 C CB . SER A 1 79 ? 0.701 -4.707 19.907 1.00 2.00 ? 79 SER A CB 1 ATOM 613 O OG . SER A 1 79 ? 0.875 -5.240 18.601 1.00 2.00 ? 79 SER A OG 1 ATOM 614 N N . ASN A 1 80 ? -0.190 -6.358 22.403 1.00 2.63 ? 80 ASN A N 1 ATOM 615 C CA . ASN A 1 80 ? -0.179 -7.615 23.148 1.00 2.00 ? 80 ASN A CA 1 ATOM 616 C C . ASN A 1 80 ? -1.573 -8.054 23.538 1.00 3.13 ? 80 ASN A C 1 ATOM 617 O O . ASN A 1 80 ? -1.964 -9.202 23.329 1.00 3.29 ? 80 ASN A O 1 ATOM 618 C CB . ASN A 1 80 ? 0.642 -7.507 24.433 1.00 2.06 ? 80 ASN A CB 1 ATOM 619 C CG . ASN A 1 80 ? 2.047 -7.029 24.190 1.00 2.51 ? 80 ASN A CG 1 ATOM 620 O OD1 . ASN A 1 80 ? 2.561 -7.110 23.078 1.00 2.95 ? 80 ASN A OD1 1 ATOM 621 N ND2 . ASN A 1 80 ? 2.691 -6.536 25.242 1.00 3.09 ? 80 ASN A ND2 1 ATOM 622 N N . LYS A 1 81 ? -2.320 -7.130 24.121 1.00 2.95 ? 81 LYS A N 1 ATOM 623 C CA . LYS A 1 81 ? -3.659 -7.438 24.576 1.00 2.98 ? 81 LYS A CA 1 ATOM 624 C C . LYS A 1 81 ? -4.658 -7.748 23.481 1.00 3.56 ? 81 LYS A C 1 ATOM 625 O O . LYS A 1 81 ? -5.471 -8.660 23.614 1.00 5.58 ? 81 LYS A O 1 ATOM 626 C CB . LYS A 1 81 ? -4.209 -6.290 25.424 1.00 3.35 ? 81 LYS A CB 1 ATOM 627 C CG . LYS A 1 81 ? -4.110 -6.526 26.920 1.00 5.07 ? 81 LYS A CG 1 ATOM 628 C CD . LYS A 1 81 ? -2.672 -6.439 27.392 1.00 8.57 ? 81 LYS A CD 1 ATOM 629 C CE . LYS A 1 81 ? -2.594 -6.396 28.918 1.00 13.40 ? 81 LYS A CE 1 ATOM 630 N NZ . LYS A 1 81 ? -2.999 -5.064 29.446 1.00 14.69 ? 81 LYS A NZ 1 ATOM 631 N N . ILE A 1 82 ? -4.584 -6.986 22.361 1.00 3.04 ? 82 ILE A N 1 ATOM 632 C CA . ILE A 1 82 ? -5.632 -7.148 21.328 1.00 2.24 ? 82 ILE A CA 1 ATOM 633 C C . ILE A 1 82 ? -5.224 -7.691 19.960 1.00 2.00 ? 82 ILE A C 1 ATOM 634 O O . ILE A 1 82 ? -5.752 -8.718 19.526 1.00 2.00 ? 82 ILE A O 1 ATOM 635 C CB . ILE A 1 82 ? -6.297 -5.809 21.075 1.00 2.00 ? 82 ILE A CB 1 ATOM 636 C CG1 . ILE A 1 82 ? -6.777 -5.214 22.401 1.00 2.00 ? 82 ILE A CG1 1 ATOM 637 C CG2 . ILE A 1 82 ? -7.466 -5.960 20.122 1.00 2.00 ? 82 ILE A CG2 1 ATOM 638 C CD1 . ILE A 1 82 ? -6.475 -3.743 22.559 1.00 2.06 ? 82 ILE A CD1 1 ATOM 639 N N . VAL A 1 83 ? -4.302 -7.004 19.313 1.00 2.44 ? 83 VAL A N 1 ATOM 640 C CA . VAL A 1 83 ? -3.919 -7.286 17.916 1.00 2.26 ? 83 VAL A CA 1 ATOM 641 C C . VAL A 1 83 ? -3.351 -8.660 17.543 1.00 3.71 ? 83 VAL A C 1 ATOM 642 O O . VAL A 1 83 ? -3.517 -9.115 16.410 1.00 2.35 ? 83 VAL A O 1 ATOM 643 C CB . VAL A 1 83 ? -2.942 -6.210 17.415 1.00 2.00 ? 83 VAL A CB 1 ATOM 644 C CG1 . VAL A 1 83 ? -2.465 -6.519 16.009 1.00 2.61 ? 83 VAL A CG1 1 ATOM 645 C CG2 . VAL A 1 83 ? -3.583 -4.837 17.475 1.00 2.00 ? 83 VAL A CG2 1 ATOM 646 N N . GLY A 1 84 ? -2.707 -9.355 18.481 1.00 3.45 ? 84 GLY A N 1 ATOM 647 C CA . GLY A 1 84 ? -2.035 -10.612 18.179 1.00 3.40 ? 84 GLY A CA 1 ATOM 648 C C . GLY A 1 84 ? -2.781 -11.914 18.497 1.00 2.00 ? 84 GLY A C 1 ATOM 649 O O . GLY A 1 84 ? -3.800 -11.944 19.185 1.00 2.00 ? 84 GLY A O 1 ATOM 650 N N . TYR A 1 85 ? -2.206 -12.999 17.983 1.00 2.00 ? 85 TYR A N 1 ATOM 651 C CA . TYR A 1 85 ? -2.726 -14.344 18.166 1.00 2.00 ? 85 TYR A CA 1 ATOM 652 C C . TYR A 1 85 ? -1.593 -15.372 17.963 1.00 3.39 ? 85 TYR A C 1 ATOM 653 O O . TYR A 1 85 ? -0.541 -15.009 17.442 1.00 4.05 ? 85 TYR A O 1 ATOM 654 C CB . TYR A 1 85 ? -3.844 -14.640 17.162 1.00 2.00 ? 85 TYR A CB 1 ATOM 655 C CG . TYR A 1 85 ? -3.460 -14.557 15.708 1.00 2.12 ? 85 TYR A CG 1 ATOM 656 C CD1 . TYR A 1 85 ? -3.237 -15.728 14.983 1.00 2.52 ? 85 TYR A CD1 1 ATOM 657 C CD2 . TYR A 1 85 ? -3.320 -13.339 15.035 1.00 2.69 ? 85 TYR A CD2 1 ATOM 658 C CE1 . TYR A 1 85 ? -2.895 -15.687 13.613 1.00 3.09 ? 85 TYR A CE1 1 ATOM 659 C CE2 . TYR A 1 85 ? -3.006 -13.287 13.667 1.00 2.90 ? 85 TYR A CE2 1 ATOM 660 C CZ . TYR A 1 85 ? -2.802 -14.463 12.962 1.00 2.08 ? 85 TYR A CZ 1 ATOM 661 O OH . TYR A 1 85 ? -2.524 -14.411 11.607 1.00 2.00 ? 85 TYR A OH 1 ATOM 662 N N . LEU A 1 86 ? -1.771 -16.659 18.394 1.00 4.74 ? 86 LEU A N 1 ATOM 663 C CA . LEU A 1 86 ? -0.701 -17.694 18.331 1.00 3.35 ? 86 LEU A CA 1 ATOM 664 C C . LEU A 1 86 ? -1.012 -18.880 17.462 1.00 2.03 ? 86 LEU A C 1 ATOM 665 O O . LEU A 1 86 ? -0.117 -19.679 17.168 1.00 2.00 ? 86 LEU A O 1 ATOM 666 C CB . LEU A 1 86 ? -0.472 -18.430 19.650 1.00 3.41 ? 86 LEU A CB 1 ATOM 667 C CG . LEU A 1 86 ? -0.086 -17.684 20.899 1.00 3.65 ? 86 LEU A CG 1 ATOM 668 C CD1 . LEU A 1 86 ? -0.244 -18.590 22.107 1.00 2.74 ? 86 LEU A CD1 1 ATOM 669 C CD2 . LEU A 1 86 ? 1.343 -17.147 20.806 1.00 4.27 ? 86 LEU A CD2 1 ATOM 670 N N . ASP A 1 87 ? -2.241 -19.036 17.063 1.00 2.00 ? 87 ASP A N 1 ATOM 671 C CA . ASP A 1 87 ? -2.574 -20.103 16.125 1.00 2.45 ? 87 ASP A CA 1 ATOM 672 C C . ASP A 1 87 ? -2.804 -19.390 14.792 1.00 3.48 ? 87 ASP A C 1 ATOM 673 O O . ASP A 1 87 ? -3.531 -18.399 14.738 1.00 2.00 ? 87 ASP A O 1 ATOM 674 C CB . ASP A 1 87 ? -3.841 -20.856 16.579 1.00 3.65 ? 87 ASP A CB 1 ATOM 675 C CG . ASP A 1 87 ? -4.301 -22.076 15.753 1.00 6.43 ? 87 ASP A CG 1 ATOM 676 O OD1 . ASP A 1 87 ? -3.481 -22.656 15.021 1.00 5.44 ? 87 ASP A OD1 1 ATOM 677 O OD2 . ASP A 1 87 ? -5.489 -22.426 15.863 1.00 7.33 ? 87 ASP A OD2 1 ATOM 678 N N . GLU A 1 88 ? -2.194 -19.913 13.741 1.00 3.75 ? 88 GLU A N 1 ATOM 679 C CA . GLU A 1 88 ? -2.386 -19.318 12.426 1.00 2.47 ? 88 GLU A CA 1 ATOM 680 C C . GLU A 1 88 ? -3.259 -20.266 11.667 1.00 2.11 ? 88 GLU A C 1 ATOM 681 O O . GLU A 1 88 ? -3.156 -20.358 10.453 1.00 2.00 ? 88 GLU A O 1 ATOM 682 C CB . GLU A 1 88 ? -1.062 -19.216 11.650 1.00 3.86 ? 88 GLU A CB 1 ATOM 683 C CG . GLU A 1 88 ? -0.137 -18.162 12.185 1.00 7.62 ? 88 GLU A CG 1 ATOM 684 C CD . GLU A 1 88 ? -0.454 -16.820 11.579 1.00 10.69 ? 88 GLU A CD 1 ATOM 685 O OE1 . GLU A 1 88 ? -0.985 -16.774 10.454 1.00 11.76 ? 88 GLU A OE1 1 ATOM 686 O OE2 . GLU A 1 88 ? -0.184 -15.792 12.235 1.00 13.26 ? 88 GLU A OE2 1 ATOM 687 N N . GLU A 1 89 ? -4.120 -20.997 12.356 1.00 3.20 ? 89 GLU A N 1 ATOM 688 C CA . GLU A 1 89 ? -4.929 -21.984 11.669 1.00 3.26 ? 89 GLU A CA 1 ATOM 689 C C . GLU A 1 89 ? -6.376 -21.619 11.447 1.00 3.34 ? 89 GLU A C 1 ATOM 690 O O . GLU A 1 89 ? -7.094 -21.237 12.378 1.00 4.34 ? 89 GLU A O 1 ATOM 691 C CB . GLU A 1 89 ? -4.840 -23.281 12.460 1.00 4.29 ? 89 GLU A CB 1 ATOM 692 C CG . GLU A 1 89 ? -5.386 -24.466 11.725 1.00 10.54 ? 89 GLU A CG 1 ATOM 693 C CD . GLU A 1 89 ? -4.943 -25.712 12.439 1.00 15.88 ? 89 GLU A CD 1 ATOM 694 O OE1 . GLU A 1 89 ? -3.716 -26.015 12.404 1.00 19.03 ? 89 GLU A OE1 1 ATOM 695 O OE2 . GLU A 1 89 ? -5.807 -26.401 13.027 1.00 20.25 ? 89 GLU A OE2 1 ATOM 696 N N . GLY A 1 90 ? -6.799 -21.728 10.196 1.00 3.46 ? 90 GLY A N 1 ATOM 697 C CA . GLY A 1 90 ? -8.169 -21.412 9.852 1.00 4.16 ? 90 GLY A CA 1 ATOM 698 C C . GLY A 1 90 ? -8.319 -19.929 9.629 1.00 4.71 ? 90 GLY A C 1 ATOM 699 O O . GLY A 1 90 ? -9.424 -19.431 9.422 1.00 7.40 ? 90 GLY A O 1 ATOM 700 N N . VAL A 1 91 ? -7.192 -19.228 9.668 1.00 4.17 ? 91 VAL A N 1 ATOM 701 C CA . VAL A 1 91 ? -7.152 -17.779 9.481 1.00 3.80 ? 91 VAL A CA 1 ATOM 702 C C . VAL A 1 91 ? -7.186 -17.359 8.000 1.00 4.84 ? 91 VAL A C 1 ATOM 703 O O . VAL A 1 91 ? -7.122 -16.162 7.686 1.00 4.38 ? 91 VAL A O 1 ATOM 704 C CB . VAL A 1 91 ? -5.868 -17.213 10.109 1.00 2.00 ? 91 VAL A CB 1 ATOM 705 C CG1 . VAL A 1 91 ? -4.641 -17.841 9.472 1.00 2.27 ? 91 VAL A CG1 1 ATOM 706 C CG2 . VAL A 1 91 ? -5.833 -15.704 9.979 1.00 2.00 ? 91 VAL A CG2 1 ATOM 707 N N . LEU A 1 92 ? -7.287 -18.337 7.095 1.00 4.33 ? 92 LEU A N 1 ATOM 708 C CA . LEU A 1 92 ? -7.257 -18.046 5.665 1.00 2.39 ? 92 LEU A CA 1 ATOM 709 C C . LEU A 1 92 ? -8.579 -17.656 5.061 1.00 2.36 ? 92 LEU A C 1 ATOM 710 O O . LEU A 1 92 ? -9.612 -18.246 5.355 1.00 3.38 ? 92 LEU A O 1 ATOM 711 C CB . LEU A 1 92 ? -6.682 -19.247 4.907 1.00 2.26 ? 92 LEU A CB 1 ATOM 712 C CG . LEU A 1 92 ? -5.158 -19.317 4.900 1.00 2.00 ? 92 LEU A CG 1 ATOM 713 C CD1 . LEU A 1 92 ? -4.654 -19.919 3.596 1.00 2.68 ? 92 LEU A CD1 1 ATOM 714 C CD2 . LEU A 1 92 ? -4.546 -17.938 5.122 1.00 2.00 ? 92 LEU A CD2 1 ATOM 715 N N . ASP A 1 93 ? -8.527 -16.649 4.230 1.00 2.00 ? 93 ASP A N 1 ATOM 716 C CA . ASP A 1 93 ? -9.714 -16.142 3.530 1.00 2.53 ? 93 ASP A CA 1 ATOM 717 C C . ASP A 1 93 ? -10.060 -17.122 2.419 1.00 3.77 ? 93 ASP A C 1 ATOM 718 O O . ASP A 1 93 ? -9.372 -17.191 1.404 1.00 3.63 ? 93 ASP A O 1 ATOM 719 C CB . ASP A 1 93 ? -9.422 -14.753 2.963 1.00 2.15 ? 93 ASP A CB 1 ATOM 720 C CG . ASP A 1 93 ? -10.638 -14.105 2.354 1.00 2.00 ? 93 ASP A CG 1 ATOM 721 O OD1 . ASP A 1 93 ? -11.223 -14.693 1.421 1.00 2.00 ? 93 ASP A OD1 1 ATOM 722 O OD2 . ASP A 1 93 ? -11.002 -13.001 2.810 1.00 2.00 ? 93 ASP A OD2 1 ATOM 723 N N . GLN A 1 94 ? -11.134 -17.878 2.608 1.00 4.68 ? 94 GLN A N 1 ATOM 724 C CA . GLN A 1 94 ? -11.522 -18.913 1.628 1.00 6.00 ? 94 GLN A CA 1 ATOM 725 C C . GLN A 1 94 ? -11.730 -18.409 0.202 1.00 6.39 ? 94 GLN A C 1 ATOM 726 O O . GLN A 1 94 ? -11.622 -19.193 -0.740 1.00 6.78 ? 94 GLN A O 1 ATOM 727 C CB . GLN A 1 94 ? -12.775 -19.632 2.098 1.00 7.54 ? 94 GLN A CB 1 ATOM 728 C CG . GLN A 1 94 ? -12.490 -20.712 3.135 1.00 10.12 ? 94 GLN A CG 1 ATOM 729 C CD . GLN A 1 94 ? -11.208 -21.472 2.840 1.00 12.14 ? 94 GLN A CD 1 ATOM 730 O OE1 . GLN A 1 94 ? -11.060 -22.062 1.765 1.00 12.75 ? 94 GLN A OE1 1 ATOM 731 N NE2 . GLN A 1 94 ? -10.167 -21.605 3.654 1.00 12.33 ? 94 GLN A NE2 1 ATOM 732 N N . ASN A 1 95 ? -12.040 -17.137 0.026 1.00 6.63 ? 95 ASN A N 1 ATOM 733 C CA . ASN A 1 95 ? -12.329 -16.644 -1.314 1.00 7.20 ? 95 ASN A CA 1 ATOM 734 C C . ASN A 1 95 ? -11.579 -15.389 -1.761 1.00 5.75 ? 95 ASN A C 1 ATOM 735 O O . ASN A 1 95 ? -12.173 -14.419 -2.258 1.00 5.15 ? 95 ASN A O 1 ATOM 736 C CB . ASN A 1 95 ? -13.819 -16.418 -1.406 1.00 11.57 ? 95 ASN A CB 1 ATOM 737 C CG . ASN A 1 95 ? -14.224 -16.117 -2.814 1.00 18.38 ? 95 ASN A CG 1 ATOM 738 O OD1 . ASN A 1 95 ? -13.550 -16.498 -3.784 1.00 15.50 ? 95 ASN A OD1 1 ATOM 739 N ND2 . ASN A 1 95 ? -15.350 -15.426 -2.954 1.00 28.95 ? 95 ASN A ND2 1 ATOM 740 N N . ARG A 1 96 ? -10.261 -15.409 -1.575 1.00 4.65 ? 96 ARG A N 1 ATOM 741 C CA . ARG A 1 96 ? -9.371 -14.303 -1.939 1.00 3.29 ? 96 ARG A CA 1 ATOM 742 C C . ARG A 1 96 ? -7.906 -14.772 -2.099 1.00 2.87 ? 96 ARG A C 1 ATOM 743 O O . ARG A 1 96 ? -7.278 -15.205 -1.131 1.00 2.00 ? 96 ARG A O 1 ATOM 744 C CB . ARG A 1 96 ? -9.434 -13.217 -0.862 1.00 2.28 ? 96 ARG A CB 1 ATOM 745 C CG . ARG A 1 96 ? -10.745 -12.452 -0.781 1.00 2.00 ? 96 ARG A CG 1 ATOM 746 C CD . ARG A 1 96 ? -10.992 -11.671 -2.058 1.00 2.74 ? 96 ARG A CD 1 ATOM 747 N NE . ARG A 1 96 ? -11.831 -10.486 -1.861 1.00 3.57 ? 96 ARG A NE 1 ATOM 748 C CZ . ARG A 1 96 ? -13.155 -10.454 -1.992 1.00 3.40 ? 96 ARG A CZ 1 ATOM 749 N NH1 . ARG A 1 96 ? -13.830 -11.546 -2.325 1.00 2.79 ? 96 ARG A NH1 1 ATOM 750 N NH2 . ARG A 1 96 ? -13.808 -9.317 -1.794 1.00 3.88 ? 96 ARG A NH2 1 ATOM 751 N N . SER A 1 97 ? -7.368 -14.677 -3.314 1.00 2.00 ? 97 SER A N 1 ATOM 752 C CA . SER A 1 97 ? -5.986 -15.080 -3.585 1.00 2.00 ? 97 SER A CA 1 ATOM 753 C C . SER A 1 97 ? -4.977 -14.203 -2.848 1.00 2.00 ? 97 SER A C 1 ATOM 754 O O . SER A 1 97 ? -5.289 -13.076 -2.484 1.00 2.00 ? 97 SER A O 1 ATOM 755 C CB . SER A 1 97 ? -5.702 -15.010 -5.091 1.00 2.14 ? 97 SER A CB 1 ATOM 756 O OG . SER A 1 97 ? -5.976 -13.713 -5.585 1.00 2.00 ? 97 SER A OG 1 ATOM 757 N N . LEU A 1 98 ? -3.765 -14.709 -2.633 1.00 2.06 ? 98 LEU A N 1 ATOM 758 C CA . LEU A 1 98 ? -2.738 -13.926 -1.942 1.00 2.00 ? 98 LEU A CA 1 ATOM 759 C C . LEU A 1 98 ? -2.475 -12.643 -2.736 1.00 2.00 ? 98 LEU A C 1 ATOM 760 O O . LEU A 1 98 ? -2.032 -11.638 -2.178 1.00 2.00 ? 98 LEU A O 1 ATOM 761 C CB . LEU A 1 98 ? -1.442 -14.767 -1.811 1.00 2.00 ? 98 LEU A CB 1 ATOM 762 C CG . LEU A 1 98 ? -0.416 -14.378 -0.731 1.00 2.00 ? 98 LEU A CG 1 ATOM 763 C CD1 . LEU A 1 98 ? 0.971 -14.236 -1.352 1.00 2.00 ? 98 LEU A CD1 1 ATOM 764 C CD2 . LEU A 1 98 ? -0.840 -13.090 -0.026 1.00 2.00 ? 98 LEU A CD2 1 ATOM 765 N N . LEU A 1 99 ? -2.767 -12.694 -4.039 1.00 2.00 ? 99 LEU A N 1 ATOM 766 C CA . LEU A 1 99 ? -2.598 -11.564 -4.957 1.00 2.00 ? 99 LEU A CA 1 ATOM 767 C C . LEU A 1 99 ? -3.414 -10.354 -4.520 1.00 2.91 ? 99 LEU A C 1 ATOM 768 O O . LEU A 1 99 ? -2.937 -9.212 -4.552 1.00 3.04 ? 99 LEU A O 1 ATOM 769 C CB . LEU A 1 99 ? -3.008 -11.951 -6.361 1.00 2.00 ? 99 LEU A CB 1 ATOM 770 C CG . LEU A 1 99 ? -3.014 -10.772 -7.329 1.00 2.00 ? 99 LEU A CG 1 ATOM 771 C CD1 . LEU A 1 99 ? -1.605 -10.305 -7.623 1.00 2.15 ? 99 LEU A CD1 1 ATOM 772 C CD2 . LEU A 1 99 ? -3.736 -11.133 -8.610 1.00 2.47 ? 99 LEU A CD2 1 ATOM 773 N N . PHE A 1 100 ? -4.659 -10.622 -4.113 1.00 2.20 ? 100 PHE A N 1 ATOM 774 C CA . PHE A 1 100 ? -5.536 -9.599 -3.558 1.00 2.00 ? 100 PHE A CA 1 ATOM 775 C C . PHE A 1 100 ? -4.719 -8.740 -2.611 1.00 2.58 ? 100 PHE A C 1 ATOM 776 O O . PHE A 1 100 ? -4.546 -7.550 -2.838 1.00 3.96 ? 100 PHE A O 1 ATOM 777 C CB . PHE A 1 100 ? -6.708 -10.245 -2.837 1.00 2.00 ? 100 PHE A CB 1 ATOM 778 C CG . PHE A 1 100 ? -7.656 -9.331 -2.132 1.00 2.67 ? 100 PHE A CG 1 ATOM 779 C CD1 . PHE A 1 100 ? -8.179 -8.233 -2.813 1.00 3.49 ? 100 PHE A CD1 1 ATOM 780 C CD2 . PHE A 1 100 ? -8.043 -9.573 -0.823 1.00 3.28 ? 100 PHE A CD2 1 ATOM 781 C CE1 . PHE A 1 100 ? -9.078 -7.383 -2.204 1.00 4.49 ? 100 PHE A CE1 1 ATOM 782 C CE2 . PHE A 1 100 ? -8.972 -8.735 -0.195 1.00 4.94 ? 100 PHE A CE2 1 ATOM 783 C CZ . PHE A 1 100 ? -9.495 -7.634 -0.890 1.00 6.38 ? 100 PHE A CZ 1 ATOM 784 N N . MET A 1 101 ? -4.227 -9.376 -1.557 1.00 3.32 ? 101 MET A N 1 ATOM 785 C CA . MET A 1 101 ? -3.410 -8.716 -0.554 1.00 2.09 ? 101 MET A CA 1 ATOM 786 C C . MET A 1 101 ? -2.327 -7.893 -1.239 1.00 2.00 ? 101 MET A C 1 ATOM 787 O O . MET A 1 101 ? -2.127 -6.718 -0.900 1.00 2.47 ? 101 MET A O 1 ATOM 788 C CB . MET A 1 101 ? -2.794 -9.775 0.368 1.00 2.00 ? 101 MET A CB 1 ATOM 789 C CG . MET A 1 101 ? -1.938 -9.196 1.490 1.00 2.00 ? 101 MET A CG 1 ATOM 790 S SD . MET A 1 101 ? -0.382 -8.524 0.877 1.00 2.00 ? 101 MET A SD 1 ATOM 791 C CE . MET A 1 101 ? 0.561 -10.018 0.610 1.00 2.00 ? 101 MET A CE 1 ATOM 792 N N . GLN A 1 102 ? -1.652 -8.515 -2.197 1.00 2.00 ? 102 GLN A N 1 ATOM 793 C CA . GLN A 1 102 ? -0.525 -7.861 -2.884 1.00 2.00 ? 102 GLN A CA 1 ATOM 794 C C . GLN A 1 102 ? -0.897 -6.660 -3.756 1.00 2.00 ? 102 GLN A C 1 ATOM 795 O O . GLN A 1 102 ? -0.120 -5.710 -3.809 1.00 2.42 ? 102 GLN A O 1 ATOM 796 C CB . GLN A 1 102 ? 0.233 -8.890 -3.699 1.00 2.00 ? 102 GLN A CB 1 ATOM 797 C CG . GLN A 1 102 ? 1.650 -8.419 -4.030 1.00 2.35 ? 102 GLN A CG 1 ATOM 798 C CD . GLN A 1 102 ? 2.498 -8.101 -2.794 1.00 2.00 ? 102 GLN A CD 1 ATOM 799 O OE1 . GLN A 1 102 ? 2.833 -8.999 -2.010 1.00 2.02 ? 102 GLN A OE1 1 ATOM 800 N NE2 . GLN A 1 102 ? 2.934 -6.900 -2.435 1.00 2.00 ? 102 GLN A NE2 1 ATOM 801 N N . TRP A 1 103 ? -2.036 -6.682 -4.445 1.00 2.57 ? 103 TRP A N 1 ATOM 802 C CA . TRP A 1 103 ? -2.379 -5.536 -5.293 1.00 2.96 ? 103 TRP A CA 1 ATOM 803 C C . TRP A 1 103 ? -2.731 -4.356 -4.409 1.00 2.45 ? 103 TRP A C 1 ATOM 804 O O . TRP A 1 103 ? -2.551 -3.208 -4.785 1.00 3.89 ? 103 TRP A O 1 ATOM 805 C CB . TRP A 1 103 ? -3.514 -5.871 -6.279 1.00 2.00 ? 103 TRP A CB 1 ATOM 806 C CG . TRP A 1 103 ? -3.720 -4.792 -7.318 1.00 2.00 ? 103 TRP A CG 1 ATOM 807 C CD1 . TRP A 1 103 ? -4.784 -3.975 -7.476 1.00 3.47 ? 103 TRP A CD1 1 ATOM 808 C CD2 . TRP A 1 103 ? -2.778 -4.423 -8.340 1.00 2.18 ? 103 TRP A CD2 1 ATOM 809 N NE1 . TRP A 1 103 ? -4.577 -3.110 -8.524 1.00 4.16 ? 103 TRP A NE1 1 ATOM 810 C CE2 . TRP A 1 103 ? -3.352 -3.365 -9.075 1.00 2.56 ? 103 TRP A CE2 1 ATOM 811 C CE3 . TRP A 1 103 ? -1.507 -4.883 -8.707 1.00 2.62 ? 103 TRP A CE3 1 ATOM 812 C CZ2 . TRP A 1 103 ? -2.704 -2.757 -10.151 1.00 2.00 ? 103 TRP A CZ2 1 ATOM 813 C CZ3 . TRP A 1 103 ? -0.863 -4.277 -9.777 1.00 2.00 ? 103 TRP A CZ3 1 ATOM 814 C CH2 . TRP A 1 103 ? -1.466 -3.225 -10.485 1.00 2.00 ? 103 TRP A CH2 1 ATOM 815 N N . GLY A 1 104 ? -3.247 -4.641 -3.220 1.00 2.00 ? 104 GLY A N 1 ATOM 816 C CA . GLY A 1 104 ? -3.595 -3.566 -2.318 1.00 2.00 ? 104 GLY A CA 1 ATOM 817 C C . GLY A 1 104 ? -2.373 -2.758 -1.935 1.00 2.00 ? 104 GLY A C 1 ATOM 818 O O . GLY A 1 104 ? -2.430 -1.535 -1.828 1.00 2.73 ? 104 GLY A O 1 ATOM 819 N N . GLN A 1 105 ? -1.256 -3.443 -1.739 1.00 2.00 ? 105 GLN A N 1 ATOM 820 C CA . GLN A 1 105 ? -0.033 -2.773 -1.342 1.00 2.00 ? 105 GLN A CA 1 ATOM 821 C C . GLN A 1 105 ? 0.574 -1.970 -2.472 1.00 2.00 ? 105 GLN A C 1 ATOM 822 O O . GLN A 1 105 ? 1.358 -1.056 -2.236 1.00 2.00 ? 105 GLN A O 1 ATOM 823 C CB . GLN A 1 105 ? 0.986 -3.788 -0.832 1.00 2.00 ? 105 GLN A CB 1 ATOM 824 C CG . GLN A 1 105 ? 2.322 -3.168 -0.515 1.00 2.00 ? 105 GLN A CG 1 ATOM 825 C CD . GLN A 1 105 ? 3.279 -4.129 0.148 1.00 2.00 ? 105 GLN A CD 1 ATOM 826 O OE1 . GLN A 1 105 ? 3.598 -5.194 -0.389 1.00 2.00 ? 105 GLN A OE1 1 ATOM 827 N NE2 . GLN A 1 105 ? 3.876 -3.971 1.330 1.00 2.76 ? 105 GLN A NE2 1 ATOM 828 N N . ILE A 1 106 ? 0.227 -2.313 -3.703 1.00 2.00 ? 106 ILE A N 1 ATOM 829 C CA . ILE A 1 106 ? 0.767 -1.590 -4.841 1.00 2.00 ? 106 ILE A CA 1 ATOM 830 C C . ILE A 1 106 ? -0.010 -0.291 -5.058 1.00 2.53 ? 106 ILE A C 1 ATOM 831 O O . ILE A 1 106 ? 0.574 0.764 -5.259 1.00 3.20 ? 106 ILE A O 1 ATOM 832 C CB . ILE A 1 106 ? 0.699 -2.451 -6.124 1.00 2.00 ? 106 ILE A CB 1 ATOM 833 C CG1 . ILE A 1 106 ? 1.685 -3.625 -6.053 1.00 2.00 ? 106 ILE A CG1 1 ATOM 834 C CG2 . ILE A 1 106 ? 0.991 -1.607 -7.357 1.00 2.00 ? 106 ILE A CG2 1 ATOM 835 C CD1 . ILE A 1 106 ? 2.795 -3.559 -7.082 1.00 2.00 ? 106 ILE A CD1 1 ATOM 836 N N . VAL A 1 107 ? -1.328 -0.407 -5.034 1.00 2.00 ? 107 VAL A N 1 ATOM 837 C CA . VAL A 1 107 ? -2.171 0.746 -5.137 1.00 2.00 ? 107 VAL A CA 1 ATOM 838 C C . VAL A 1 107 ? -1.842 1.746 -4.051 1.00 2.00 ? 107 VAL A C 1 ATOM 839 O O . VAL A 1 107 ? -1.823 2.946 -4.313 1.00 2.26 ? 107 VAL A O 1 ATOM 840 C CB . VAL A 1 107 ? -3.669 0.363 -5.062 1.00 2.14 ? 107 VAL A CB 1 ATOM 841 C CG1 . VAL A 1 107 ? -4.547 1.591 -5.236 1.00 2.00 ? 107 VAL A CG1 1 ATOM 842 C CG2 . VAL A 1 107 ? -4.004 -0.670 -6.112 1.00 3.06 ? 107 VAL A CG2 1 ATOM 843 N N . ASP A 1 108 ? -1.569 1.267 -2.787 1.00 2.00 ? 108 ASP A N 1 ATOM 844 C CA . ASP A 1 108 ? -1.214 2.159 -1.625 1.00 2.00 ? 108 ASP A CA 1 ATOM 845 C C . ASP A 1 108 ? 0.097 2.893 -1.880 1.00 2.00 ? 108 ASP A C 1 ATOM 846 O O . ASP A 1 108 ? 0.163 4.109 -1.713 1.00 2.00 ? 108 ASP A O 1 ATOM 847 C CB . ASP A 1 108 ? -1.069 1.404 -0.286 1.00 3.53 ? 108 ASP A CB 1 ATOM 848 C CG . ASP A 1 108 ? -0.521 2.247 0.872 1.00 4.12 ? 108 ASP A CG 1 ATOM 849 O OD1 . ASP A 1 108 ? 0.702 2.467 0.919 1.00 2.00 ? 108 ASP A OD1 1 ATOM 850 O OD2 . ASP A 1 108 ? -1.318 2.686 1.715 1.00 7.85 ? 108 ASP A OD2 1 ATOM 851 N N . HIS A 1 109 ? 1.146 2.172 -2.275 1.00 2.44 ? 109 HIS A N 1 ATOM 852 C CA . HIS A 1 109 ? 2.474 2.754 -2.511 1.00 2.00 ? 109 HIS A CA 1 ATOM 853 C C . HIS A 1 109 ? 2.483 3.763 -3.661 1.00 2.00 ? 109 HIS A C 1 ATOM 854 O O . HIS A 1 109 ? 3.368 4.636 -3.694 1.00 2.13 ? 109 HIS A O 1 ATOM 855 C CB . HIS A 1 109 ? 3.474 1.649 -2.783 1.00 3.47 ? 109 HIS A CB 1 ATOM 856 C CG . HIS A 1 109 ? 4.041 1.022 -1.498 1.00 2.66 ? 109 HIS A CG 1 ATOM 857 N ND1 . HIS A 1 109 ? 4.781 -0.140 -1.510 1.00 2.10 ? 109 HIS A ND1 1 ATOM 858 C CD2 . HIS A 1 109 ? 3.985 1.415 -0.203 1.00 2.34 ? 109 HIS A CD2 1 ATOM 859 C CE1 . HIS A 1 109 ? 5.157 -0.435 -0.281 1.00 2.00 ? 109 HIS A CE1 1 ATOM 860 N NE2 . HIS A 1 109 ? 4.686 0.495 0.531 1.00 2.00 ? 109 HIS A NE2 1 ATOM 861 N N . ASP A 1 110 ? 1.512 3.689 -4.651 1.00 2.00 ? 110 ASP A N 1 ATOM 862 C CA . ASP A 1 110 ? 1.364 4.597 -5.802 1.00 2.00 ? 110 ASP A CA 1 ATOM 863 C C . ASP A 1 110 ? 0.787 5.898 -5.267 1.00 2.00 ? 110 ASP A C 1 ATOM 864 O O . ASP A 1 110 ? 0.977 6.961 -5.859 1.00 2.00 ? 110 ASP A O 1 ATOM 865 C CB . ASP A 1 110 ? 0.414 3.984 -6.862 1.00 2.00 ? 110 ASP A CB 1 ATOM 866 C CG . ASP A 1 110 ? 0.420 4.687 -8.201 1.00 2.58 ? 110 ASP A CG 1 ATOM 867 O OD1 . ASP A 1 110 ? 0.498 5.928 -8.250 1.00 2.00 ? 110 ASP A OD1 1 ATOM 868 O OD2 . ASP A 1 110 ? 0.356 3.987 -9.243 1.00 2.58 ? 110 ASP A OD2 1 ATOM 869 N N . LEU A 1 111 ? 0.063 5.815 -4.125 1.00 2.94 ? 111 LEU A N 1 ATOM 870 C CA . LEU A 1 111 ? -0.625 6.971 -3.574 1.00 2.00 ? 111 LEU A CA 1 ATOM 871 C C . LEU A 1 111 ? 0.033 7.715 -2.427 1.00 2.00 ? 111 LEU A C 1 ATOM 872 O O . LEU A 1 111 ? -0.234 8.915 -2.277 1.00 2.00 ? 111 LEU A O 1 ATOM 873 C CB . LEU A 1 111 ? -2.061 6.570 -3.202 1.00 2.00 ? 111 LEU A CB 1 ATOM 874 C CG . LEU A 1 111 ? -2.895 5.987 -4.333 1.00 2.00 ? 111 LEU A CG 1 ATOM 875 C CD1 . LEU A 1 111 ? -4.137 5.327 -3.777 1.00 2.00 ? 111 LEU A CD1 1 ATOM 876 C CD2 . LEU A 1 111 ? -3.263 7.054 -5.356 1.00 2.00 ? 111 LEU A CD2 1 ATOM 877 N N . ASP A 1 112 ? 0.841 7.113 -1.548 1.00 2.00 ? 112 ASP A N 1 ATOM 878 C CA . ASP A 1 112 ? 1.289 7.899 -0.402 1.00 2.72 ? 112 ASP A CA 1 ATOM 879 C C . ASP A 1 112 ? 2.596 7.381 0.268 1.00 2.19 ? 112 ASP A C 1 ATOM 880 O O . ASP A 1 112 ? 2.761 6.179 0.522 1.00 2.00 ? 112 ASP A O 1 ATOM 881 C CB . ASP A 1 112 ? 0.074 8.035 0.675 1.00 2.46 ? 112 ASP A CB 1 ATOM 882 C CG . ASP A 1 112 ? -0.701 6.828 1.308 1.00 2.00 ? 112 ASP A CG 1 ATOM 883 O OD1 . ASP A 1 112 ? -1.439 6.141 0.569 1.00 2.00 ? 112 ASP A OD1 1 ATOM 884 O OD2 . ASP A 1 112 ? -0.540 6.581 2.518 1.00 2.00 ? 112 ASP A OD2 1 ATOM 885 N N . PHE A 1 113 ? 3.560 8.353 0.560 1.00 2.00 ? 113 PHE A N 1 ATOM 886 C CA . PHE A 1 113 ? 4.778 8.119 1.350 1.00 2.51 ? 113 PHE A CA 1 ATOM 887 C C . PHE A 1 113 ? 5.021 9.299 2.318 1.00 2.00 ? 113 PHE A C 1 ATOM 888 O O . PHE A 1 113 ? 5.305 10.393 1.863 1.00 2.00 ? 113 PHE A O 1 ATOM 889 C CB . PHE A 1 113 ? 6.033 7.989 0.487 1.00 2.59 ? 113 PHE A CB 1 ATOM 890 C CG . PHE A 1 113 ? 7.184 7.258 1.180 1.00 2.84 ? 113 PHE A CG 1 ATOM 891 C CD1 . PHE A 1 113 ? 7.047 6.784 2.486 1.00 2.00 ? 113 PHE A CD1 1 ATOM 892 C CD2 . PHE A 1 113 ? 8.389 7.058 0.519 1.00 3.48 ? 113 PHE A CD2 1 ATOM 893 C CE1 . PHE A 1 113 ? 8.084 6.121 3.109 1.00 2.00 ? 113 PHE A CE1 1 ATOM 894 C CE2 . PHE A 1 113 ? 9.431 6.363 1.139 1.00 4.39 ? 113 PHE A CE2 1 ATOM 895 C CZ . PHE A 1 113 ? 9.276 5.893 2.433 1.00 2.91 ? 113 PHE A CZ 1 ATOM 896 N N . ALA A 1 114 ? 4.896 9.104 3.647 1.00 2.00 ? 114 ALA A N 1 ATOM 897 C CA . ALA A 1 114 ? 5.282 10.097 4.638 1.00 2.00 ? 114 ALA A CA 1 ATOM 898 C C . ALA A 1 114 ? 6.656 9.590 5.113 1.00 3.79 ? 114 ALA A C 1 ATOM 899 O O . ALA A 1 114 ? 6.759 8.574 5.780 1.00 3.65 ? 114 ALA A O 1 ATOM 900 C CB . ALA A 1 114 ? 4.260 10.213 5.767 1.00 2.00 ? 114 ALA A CB 1 ATOM 901 N N . PRO A 1 115 ? 7.711 10.342 4.682 1.00 4.91 ? 115 PRO A N 1 ATOM 902 C CA . PRO A 1 115 ? 9.074 9.990 5.055 1.00 7.29 ? 115 PRO A CA 1 ATOM 903 C C . PRO A 1 115 ? 9.341 9.993 6.514 1.00 11.61 ? 115 PRO A C 1 ATOM 904 O O . PRO A 1 115 ? 9.157 11.045 7.134 1.00 11.39 ? 115 PRO A O 1 ATOM 905 C CB . PRO A 1 115 ? 9.934 11.004 4.375 1.00 6.95 ? 115 PRO A CB 1 ATOM 906 C CG . PRO A 1 115 ? 9.261 11.089 3.049 1.00 5.33 ? 115 PRO A CG 1 ATOM 907 C CD . PRO A 1 115 ? 7.840 10.668 3.262 1.00 5.32 ? 115 PRO A CD 1 ATOM 908 N N . GLU A 1 116 ? 9.769 8.929 7.185 1.00 17.12 ? 116 GLU A N 1 ATOM 909 C CA . GLU A 1 116 ? 10.090 9.420 8.524 1.00 21.91 ? 116 GLU A CA 1 ATOM 910 C C . GLU A 1 116 ? 11.386 10.292 8.345 1.00 25.09 ? 116 GLU A C 1 ATOM 911 O O . GLU A 1 116 ? 12.097 10.236 7.334 1.00 24.49 ? 116 GLU A O 1 ATOM 912 C CB . GLU A 1 116 ? 10.125 8.315 9.547 1.00 20.97 ? 116 GLU A CB 1 ATOM 913 C CG . GLU A 1 116 ? 10.022 6.937 8.982 1.00 22.31 ? 116 GLU A CG 1 ATOM 914 C CD . GLU A 1 116 ? 11.187 6.220 9.581 1.00 22.99 ? 116 GLU A CD 1 ATOM 915 O OE1 . GLU A 1 116 ? 12.286 6.267 9.006 1.00 23.60 ? 116 GLU A OE1 1 ATOM 916 O OE2 . GLU A 1 116 ? 11.020 5.611 10.663 1.00 22.77 ? 116 GLU A OE2 1 ATOM 917 N N . THR A 1 117 ? 11.607 11.104 9.411 1.00 29.01 ? 117 THR A N 1 ATOM 918 C CA . THR A 1 117 ? 12.548 12.211 9.543 1.00 32.56 ? 117 THR A CA 1 ATOM 919 C C . THR A 1 117 ? 13.997 12.052 9.322 1.00 36.34 ? 117 THR A C 1 ATOM 920 O O . THR A 1 117 ? 14.497 11.936 8.215 1.00 37.24 ? 117 THR A O 1 ATOM 921 C CB . THR A 1 117 ? 12.535 12.785 10.963 1.00 31.54 ? 117 THR A CB 1 ATOM 922 O OG1 . THR A 1 117 ? 11.965 11.825 11.855 1.00 31.20 ? 117 THR A OG1 1 ATOM 923 C CG2 . THR A 1 117 ? 11.735 14.069 11.009 1.00 31.90 ? 117 THR A CG2 1 ATOM 924 N N . GLU A 1 118 ? 14.642 12.063 10.389 1.00 41.56 ? 118 GLU A N 1 ATOM 925 C CA . GLU A 1 118 ? 15.967 12.206 10.195 1.00 46.34 ? 118 GLU A CA 1 ATOM 926 C C . GLU A 1 118 ? 16.835 11.013 10.028 1.00 47.53 ? 118 GLU A C 1 ATOM 927 O O . GLU A 1 118 ? 16.545 9.860 10.323 1.00 47.12 ? 118 GLU A O 1 ATOM 928 C CB . GLU A 1 118 ? 16.521 13.095 11.307 1.00 49.07 ? 118 GLU A CB 1 ATOM 929 C CG . GLU A 1 118 ? 17.347 14.226 10.712 1.00 51.16 ? 118 GLU A CG 1 ATOM 930 C CD . GLU A 1 118 ? 16.606 15.556 10.661 1.00 52.17 ? 118 GLU A CD 1 ATOM 931 O OE1 . GLU A 1 118 ? 15.600 15.676 9.930 1.00 52.45 ? 118 GLU A OE1 1 ATOM 932 O OE2 . GLU A 1 118 ? 17.053 16.477 11.359 1.00 52.33 ? 118 GLU A OE2 1 ATOM 933 N N . LEU A 1 119 ? 17.928 11.448 9.510 1.00 49.81 ? 119 LEU A N 1 ATOM 934 C CA . LEU A 1 119 ? 19.059 10.614 9.289 1.00 51.66 ? 119 LEU A CA 1 ATOM 935 C C . LEU A 1 119 ? 20.091 11.153 10.259 1.00 52.73 ? 119 LEU A C 1 ATOM 936 O O . LEU A 1 119 ? 20.150 10.778 11.443 1.00 52.76 ? 119 LEU A O 1 ATOM 937 C CB . LEU A 1 119 ? 19.568 10.688 7.829 1.00 50.98 ? 119 LEU A CB 1 ATOM 938 C CG . LEU A 1 119 ? 19.244 11.923 6.955 1.00 51.16 ? 119 LEU A CG 1 ATOM 939 C CD1 . LEU A 1 119 ? 17.763 12.003 6.653 1.00 51.59 ? 119 LEU A CD1 1 ATOM 940 C CD2 . LEU A 1 119 ? 19.719 13.193 7.634 1.00 50.46 ? 119 LEU A CD2 1 ATOM 941 N N . GLY A 1 120 ? 20.879 12.050 9.712 1.00 53.92 ? 120 GLY A N 1 ATOM 942 C CA . GLY A 1 120 ? 21.897 12.708 10.406 1.00 55.12 ? 120 GLY A CA 1 ATOM 943 C C . GLY A 1 120 ? 23.077 12.827 9.488 1.00 55.49 ? 120 GLY A C 1 ATOM 944 O O . GLY A 1 120 ? 23.508 13.919 9.111 1.00 55.92 ? 120 GLY A O 1 ATOM 945 N N . SER A 1 121 ? 23.613 11.619 9.089 1.00 55.64 ? 121 SER A N 1 ATOM 946 C CA . SER A 1 121 ? 24.858 11.495 8.288 1.00 55.91 ? 121 SER A CA 1 ATOM 947 C C . SER A 1 121 ? 25.927 11.596 9.273 1.00 55.48 ? 121 SER A C 1 ATOM 948 O O . SER A 1 121 ? 26.482 12.642 9.598 1.00 55.22 ? 121 SER A O 1 ATOM 949 C CB . SER A 1 121 ? 25.061 12.632 7.284 1.00 55.95 ? 121 SER A CB 1 ATOM 950 O OG . SER A 1 121 ? 23.950 12.754 6.412 1.00 55.38 ? 121 SER A OG 1 ATOM 951 N N . SER A 1 122 ? 26.235 10.426 9.780 1.00 55.52 ? 122 SER A N 1 ATOM 952 C CA . SER A 1 122 ? 27.162 10.241 10.868 1.00 56.58 ? 122 SER A CA 1 ATOM 953 C C . SER A 1 122 ? 26.567 10.964 12.072 1.00 55.54 ? 122 SER A C 1 ATOM 954 O O . SER A 1 122 ? 26.873 12.113 12.375 1.00 54.85 ? 122 SER A O 1 ATOM 955 C CB . SER A 1 122 ? 28.583 10.762 10.533 1.00 57.76 ? 122 SER A CB 1 ATOM 956 O OG . SER A 1 122 ? 29.563 10.058 11.285 1.00 58.85 ? 122 SER A OG 1 ATOM 957 N N . GLU A 1 123 ? 25.681 10.229 12.773 1.00 53.67 ? 123 GLU A N 1 ATOM 958 C CA . GLU A 1 123 ? 24.992 10.795 13.893 1.00 51.79 ? 123 GLU A CA 1 ATOM 959 C C . GLU A 1 123 ? 25.099 10.036 15.224 1.00 51.18 ? 123 GLU A C 1 ATOM 960 O O . GLU A 1 123 ? 25.139 8.807 15.289 1.00 49.57 ? 123 GLU A O 1 ATOM 961 C CB . GLU A 1 123 ? 23.538 10.991 13.456 1.00 51.71 ? 123 GLU A CB 1 ATOM 962 C CG . GLU A 1 123 ? 22.678 11.723 14.460 1.00 52.14 ? 123 GLU A CG 1 ATOM 963 C CD . GLU A 1 123 ? 22.633 13.220 14.233 1.00 52.56 ? 123 GLU A CD 1 ATOM 964 O OE1 . GLU A 1 123 ? 21.986 13.643 13.256 1.00 53.06 ? 123 GLU A OE1 1 ATOM 965 O OE2 . GLU A 1 123 ? 23.232 13.969 15.045 1.00 52.28 ? 123 GLU A OE2 1 ATOM 966 N N . HIS A 1 124 ? 25.185 10.827 16.283 1.00 50.82 ? 124 HIS A N 1 ATOM 967 C CA . HIS A 1 124 ? 25.268 10.336 17.646 1.00 50.15 ? 124 HIS A CA 1 ATOM 968 C C . HIS A 1 124 ? 23.896 10.259 18.209 1.00 48.02 ? 124 HIS A C 1 ATOM 969 O O . HIS A 1 124 ? 23.707 9.865 19.359 1.00 47.19 ? 124 HIS A O 1 ATOM 970 C CB . HIS A 1 124 ? 26.051 11.329 18.487 1.00 54.00 ? 124 HIS A CB 1 ATOM 971 C CG . HIS A 1 124 ? 27.415 10.834 18.981 1.00 57.13 ? 124 HIS A CG 1 ATOM 972 N ND1 . HIS A 1 124 ? 28.593 11.193 18.370 1.00 58.15 ? 124 HIS A ND1 1 ATOM 973 C CD2 . HIS A 1 124 ? 27.756 10.039 20.024 1.00 58.14 ? 124 HIS A CD2 1 ATOM 974 C CE1 . HIS A 1 124 ? 29.607 10.650 19.016 1.00 59.11 ? 124 HIS A CE1 1 ATOM 975 N NE2 . HIS A 1 124 ? 29.127 9.946 20.026 1.00 59.29 ? 124 HIS A NE2 1 ATOM 976 N N . SER A 1 125 ? 22.911 10.645 17.403 1.00 45.73 ? 125 SER A N 1 ATOM 977 C CA . SER A 1 125 ? 21.535 10.673 17.876 1.00 43.81 ? 125 SER A CA 1 ATOM 978 C C . SER A 1 125 ? 20.660 9.482 17.503 1.00 42.05 ? 125 SER A C 1 ATOM 979 O O . SER A 1 125 ? 19.622 9.264 18.126 1.00 43.23 ? 125 SER A O 1 ATOM 980 C CB . SER A 1 125 ? 20.856 11.972 17.419 1.00 43.56 ? 125 SER A CB 1 ATOM 981 O OG . SER A 1 125 ? 20.398 11.879 16.083 1.00 42.15 ? 125 SER A OG 1 ATOM 982 N N . LYS A 1 126 ? 21.048 8.725 16.484 1.00 38.72 ? 126 LYS A N 1 ATOM 983 C CA . LYS A 1 126 ? 20.300 7.509 16.142 1.00 34.57 ? 126 LYS A CA 1 ATOM 984 C C . LYS A 1 126 ? 20.626 6.537 17.262 1.00 33.74 ? 126 LYS A C 1 ATOM 985 O O . LYS A 1 126 ? 19.845 5.656 17.624 1.00 32.82 ? 126 LYS A O 1 ATOM 986 C CB . LYS A 1 126 ? 20.751 6.908 14.821 1.00 31.90 ? 126 LYS A CB 1 ATOM 987 C CG . LYS A 1 126 ? 20.877 7.884 13.669 1.00 29.25 ? 126 LYS A CG 1 ATOM 988 C CD . LYS A 1 126 ? 21.311 7.174 12.394 1.00 27.81 ? 126 LYS A CD 1 ATOM 989 C CE . LYS A 1 126 ? 21.619 8.160 11.280 1.00 26.56 ? 126 LYS A CE 1 ATOM 990 N NZ . LYS A 1 126 ? 22.868 8.925 11.550 1.00 25.08 ? 126 LYS A NZ 1 ATOM 991 N N . VAL A 1 127 ? 21.814 6.742 17.809 1.00 34.12 ? 127 VAL A N 1 ATOM 992 C CA . VAL A 1 127 ? 22.337 5.933 18.882 1.00 35.33 ? 127 VAL A CA 1 ATOM 993 C C . VAL A 1 127 ? 21.635 6.181 20.224 1.00 34.61 ? 127 VAL A C 1 ATOM 994 O O . VAL A 1 127 ? 21.546 5.272 21.044 1.00 34.75 ? 127 VAL A O 1 ATOM 995 C CB . VAL A 1 127 ? 23.846 6.198 19.053 1.00 36.03 ? 127 VAL A CB 1 ATOM 996 C CG1 . VAL A 1 127 ? 24.507 5.059 19.831 1.00 37.02 ? 127 VAL A CG1 1 ATOM 997 C CG2 . VAL A 1 127 ? 24.511 6.369 17.686 1.00 36.11 ? 127 VAL A CG2 1 ATOM 998 N N . GLN A 1 128 ? 21.124 7.393 20.475 1.00 33.73 ? 128 GLN A N 1 ATOM 999 C CA . GLN A 1 128 ? 20.481 7.732 21.753 1.00 32.01 ? 128 GLN A CA 1 ATOM 1000 C C . GLN A 1 128 ? 19.035 7.267 21.863 1.00 30.83 ? 128 GLN A C 1 ATOM 1001 O O . GLN A 1 128 ? 18.391 7.417 22.901 1.00 30.46 ? 128 GLN A O 1 ATOM 1002 C CB . GLN A 1 128 ? 20.573 9.247 21.987 1.00 33.87 ? 128 GLN A CB 1 ATOM 1003 C CG . GLN A 1 128 ? 20.418 9.679 23.432 1.00 35.14 ? 128 GLN A CG 1 ATOM 1004 C CD . GLN A 1 128 ? 20.876 11.113 23.676 1.00 36.00 ? 128 GLN A CD 1 ATOM 1005 O OE1 . GLN A 1 128 ? 20.052 12.030 23.742 1.00 35.71 ? 128 GLN A OE1 1 ATOM 1006 N NE2 . GLN A 1 128 ? 22.137 11.513 23.833 1.00 35.39 ? 128 GLN A NE2 1 ATOM 1007 N N . CYS A 1 129 ? 18.504 6.714 20.782 1.00 29.02 ? 129 CYS A N 1 ATOM 1008 C CA . CYS A 1 129 ? 17.122 6.252 20.706 1.00 27.15 ? 129 CYS A CA 1 ATOM 1009 C C . CYS A 1 129 ? 17.032 4.702 20.633 1.00 27.50 ? 129 CYS A C 1 ATOM 1010 O O . CYS A 1 129 ? 16.003 4.099 20.993 1.00 27.99 ? 129 CYS A O 1 ATOM 1011 C CB . CYS A 1 129 ? 16.455 6.865 19.471 1.00 23.78 ? 129 CYS A CB 1 ATOM 1012 S SG . CYS A 1 129 ? 14.643 7.033 19.605 1.00 20.08 ? 129 CYS A SG 1 ATOM 1013 N N . GLU A 1 130 ? 18.115 4.079 20.162 1.00 27.25 ? 130 GLU A N 1 ATOM 1014 C CA . GLU A 1 130 ? 18.207 2.622 20.033 1.00 28.02 ? 130 GLU A CA 1 ATOM 1015 C C . GLU A 1 130 ? 19.138 2.036 21.117 1.00 29.25 ? 130 GLU A C 1 ATOM 1016 O O . GLU A 1 130 ? 19.733 0.973 20.922 1.00 31.08 ? 130 GLU A O 1 ATOM 1017 C CB . GLU A 1 130 ? 18.713 2.253 18.644 1.00 29.13 ? 130 GLU A CB 1 ATOM 1018 C CG . GLU A 1 130 ? 18.676 0.762 18.325 1.00 30.87 ? 130 GLU A CG 1 ATOM 1019 C CD . GLU A 1 130 ? 19.042 0.436 16.884 1.00 31.83 ? 130 GLU A CD 1 ATOM 1020 O OE1 . GLU A 1 130 ? 18.877 -0.743 16.494 1.00 31.84 ? 130 GLU A OE1 1 ATOM 1021 O OE2 . GLU A 1 130 ? 19.490 1.344 16.142 1.00 31.58 ? 130 GLU A OE2 1 ATOM 1022 N N . GLU A 1 131 ? 19.263 2.717 22.258 1.00 27.94 ? 131 GLU A N 1 ATOM 1023 C CA . GLU A 1 131 ? 20.145 2.245 23.329 1.00 25.75 ? 131 GLU A CA 1 ATOM 1024 C C . GLU A 1 131 ? 19.646 2.621 24.714 1.00 25.58 ? 131 GLU A C 1 ATOM 1025 O O . GLU A 1 131 ? 19.586 1.782 25.611 1.00 25.18 ? 131 GLU A O 1 ATOM 1026 C CB . GLU A 1 131 ? 21.552 2.822 23.148 1.00 27.69 ? 131 GLU A CB 1 ATOM 1027 C CG . GLU A 1 131 ? 22.221 2.490 21.816 1.00 30.67 ? 131 GLU A CG 1 ATOM 1028 C CD . GLU A 1 131 ? 22.979 1.171 21.837 1.00 31.82 ? 131 GLU A CD 1 ATOM 1029 O OE1 . GLU A 1 131 ? 22.379 0.135 22.209 1.00 32.69 ? 131 GLU A OE1 1 ATOM 1030 O OE2 . GLU A 1 131 ? 24.178 1.176 21.474 1.00 32.09 ? 131 GLU A OE2 1 ATOM 1031 N N . TYR A 1 132 ? 19.295 3.891 24.888 1.00 25.37 ? 132 TYR A N 1 ATOM 1032 C CA . TYR A 1 132 ? 18.821 4.387 26.179 1.00 24.23 ? 132 TYR A CA 1 ATOM 1033 C C . TYR A 1 132 ? 17.329 4.707 26.137 1.00 23.07 ? 132 TYR A C 1 ATOM 1034 O O . TYR A 1 132 ? 16.721 5.035 27.165 1.00 22.73 ? 132 TYR A O 1 ATOM 1035 C CB . TYR A 1 132 ? 19.624 5.628 26.578 1.00 25.67 ? 132 TYR A CB 1 ATOM 1036 C CG . TYR A 1 132 ? 21.044 5.598 26.050 1.00 28.47 ? 132 TYR A CG 1 ATOM 1037 C CD1 . TYR A 1 132 ? 21.302 5.810 24.691 1.00 29.76 ? 132 TYR A CD1 1 ATOM 1038 C CD2 . TYR A 1 132 ? 22.129 5.332 26.892 1.00 28.65 ? 132 TYR A CD2 1 ATOM 1039 C CE1 . TYR A 1 132 ? 22.597 5.759 24.178 1.00 30.34 ? 132 TYR A CE1 1 ATOM 1040 C CE2 . TYR A 1 132 ? 23.437 5.277 26.385 1.00 29.77 ? 132 TYR A CE2 1 ATOM 1041 C CZ . TYR A 1 132 ? 23.655 5.493 25.024 1.00 30.13 ? 132 TYR A CZ 1 ATOM 1042 O OH . TYR A 1 132 ? 24.921 5.450 24.521 1.00 30.89 ? 132 TYR A OH 1 ATOM 1043 N N . CYS A 1 133 ? 16.745 4.605 24.942 1.00 20.48 ? 133 CYS A N 1 ATOM 1044 C CA . CYS A 1 133 ? 15.322 4.856 24.766 1.00 17.42 ? 133 CYS A CA 1 ATOM 1045 C C . CYS A 1 133 ? 14.907 6.149 25.452 1.00 17.49 ? 133 CYS A C 1 ATOM 1046 O O . CYS A 1 133 ? 14.013 6.165 26.307 1.00 16.04 ? 133 CYS A O 1 ATOM 1047 C CB . CYS A 1 133 ? 14.498 3.697 25.322 1.00 15.90 ? 133 CYS A CB 1 ATOM 1048 S SG . CYS A 1 133 ? 14.825 2.091 24.529 1.00 12.40 ? 133 CYS A SG 1 ATOM 1049 N N . ILE A 1 134 ? 15.566 7.235 25.073 1.00 16.99 ? 134 ILE A N 1 ATOM 1050 C CA . ILE A 1 134 ? 15.264 8.518 25.665 1.00 16.44 ? 134 ILE A CA 1 ATOM 1051 C C . ILE A 1 134 ? 14.450 9.353 24.692 1.00 15.87 ? 134 ILE A C 1 ATOM 1052 O O . ILE A 1 134 ? 14.832 9.562 23.537 1.00 14.03 ? 134 ILE A O 1 ATOM 1053 C CB . ILE A 1 134 ? 16.560 9.268 26.056 1.00 17.71 ? 134 ILE A CB 1 ATOM 1054 C CG1 . ILE A 1 134 ? 17.564 8.328 26.718 1.00 19.00 ? 134 ILE A CG1 1 ATOM 1055 C CG2 . ILE A 1 134 ? 16.250 10.447 26.968 1.00 18.22 ? 134 ILE A CG2 1 ATOM 1056 C CD1 . ILE A 1 134 ? 18.142 8.853 28.013 1.00 19.42 ? 134 ILE A CD1 1 ATOM 1057 N N . GLN A 1 135 ? 13.311 9.802 25.180 1.00 16.47 ? 135 GLN A N 1 ATOM 1058 C CA . GLN A 1 135 ? 12.393 10.678 24.452 1.00 15.80 ? 135 GLN A CA 1 ATOM 1059 C C . GLN A 1 135 ? 13.123 11.978 24.090 1.00 14.81 ? 135 GLN A C 1 ATOM 1060 O O . GLN A 1 135 ? 13.888 12.508 24.896 1.00 14.08 ? 135 GLN A O 1 ATOM 1061 C CB . GLN A 1 135 ? 11.186 11.032 25.324 1.00 18.34 ? 135 GLN A CB 1 ATOM 1062 C CG . GLN A 1 135 ? 9.900 11.232 24.563 1.00 21.42 ? 135 GLN A CG 1 ATOM 1063 C CD . GLN A 1 135 ? 8.903 10.129 24.843 1.00 24.08 ? 135 GLN A CD 1 ATOM 1064 O OE1 . GLN A 1 135 ? 7.696 10.315 24.689 1.00 26.41 ? 135 GLN A OE1 1 ATOM 1065 N NE2 . GLN A 1 135 ? 9.185 8.903 25.255 1.00 26.07 ? 135 GLN A NE2 1 ATOM 1066 N N . GLY A 1 136 ? 12.885 12.536 22.887 1.00 14.35 ? 136 GLY A N 1 ATOM 1067 C CA . GLY A 1 136 ? 13.531 13.769 22.516 1.00 14.57 ? 136 GLY A CA 1 ATOM 1068 C C . GLY A 1 136 ? 13.330 14.266 21.077 1.00 14.49 ? 136 GLY A C 1 ATOM 1069 O O . GLY A 1 136 ? 14.018 13.820 20.156 1.00 14.01 ? 136 GLY A O 1 ATOM 1070 N N . ASP A 1 137 ? 12.401 15.205 20.865 1.00 14.77 ? 137 ASP A N 1 ATOM 1071 C CA . ASP A 1 137 ? 12.155 15.938 19.559 1.00 15.90 ? 137 ASP A CA 1 ATOM 1072 C C . ASP A 1 137 ? 12.143 15.225 18.197 1.00 14.24 ? 137 ASP A C 1 ATOM 1073 O O . ASP A 1 137 ? 11.499 15.695 17.272 1.00 14.31 ? 137 ASP A O 1 ATOM 1074 C CB . ASP A 1 137 ? 13.249 17.016 19.388 1.00 19.06 ? 137 ASP A CB 1 ATOM 1075 C CG . ASP A 1 137 ? 14.257 16.707 18.256 1.00 21.20 ? 137 ASP A CG 1 ATOM 1076 O OD1 . ASP A 1 137 ? 14.603 15.531 18.076 1.00 21.65 ? 137 ASP A OD1 1 ATOM 1077 O OD2 . ASP A 1 137 ? 14.675 17.662 17.582 1.00 21.74 ? 137 ASP A OD2 1 ATOM 1078 N N . ASN A 1 138 ? 12.832 14.102 18.072 1.00 10.84 ? 138 ASN A N 1 ATOM 1079 C CA . ASN A 1 138 ? 12.724 13.435 16.784 1.00 9.53 ? 138 ASN A CA 1 ATOM 1080 C C . ASN A 1 138 ? 12.575 11.982 17.029 1.00 6.80 ? 138 ASN A C 1 ATOM 1081 O O . ASN A 1 138 ? 12.213 11.193 16.143 1.00 5.46 ? 138 ASN A O 1 ATOM 1082 C CB . ASN A 1 138 ? 13.896 13.762 15.840 1.00 12.26 ? 138 ASN A CB 1 ATOM 1083 C CG . ASN A 1 138 ? 13.434 14.418 14.542 1.00 16.49 ? 138 ASN A CG 1 ATOM 1084 O OD1 . ASN A 1 138 ? 13.305 13.764 13.505 1.00 16.23 ? 138 ASN A OD1 1 ATOM 1085 N ND2 . ASN A 1 138 ? 13.203 15.730 14.601 1.00 17.02 ? 138 ASN A ND2 1 ATOM 1086 N N . CYS A 1 139 ? 12.861 11.644 18.257 1.00 5.59 ? 139 CYS A N 1 ATOM 1087 C CA . CYS A 1 139 ? 12.780 10.282 18.674 1.00 4.92 ? 139 CYS A CA 1 ATOM 1088 C C . CYS A 1 139 ? 11.642 10.137 19.693 1.00 3.36 ? 139 CYS A C 1 ATOM 1089 O O . CYS A 1 139 ? 11.714 10.652 20.803 1.00 3.14 ? 139 CYS A O 1 ATOM 1090 C CB . CYS A 1 139 ? 14.141 9.824 19.233 1.00 8.98 ? 139 CYS A CB 1 ATOM 1091 S SG . CYS A 1 139 ? 14.022 8.542 20.526 1.00 15.52 ? 139 CYS A SG 1 ATOM 1092 N N . PHE A 1 140 ? 10.620 9.416 19.316 1.00 3.62 ? 140 PHE A N 1 ATOM 1093 C CA . PHE A 1 140 ? 9.432 9.142 20.144 1.00 3.67 ? 140 PHE A CA 1 ATOM 1094 C C . PHE A 1 140 ? 9.370 7.596 20.250 1.00 5.32 ? 140 PHE A C 1 ATOM 1095 O O . PHE A 1 140 ? 8.839 6.923 19.375 1.00 7.17 ? 140 PHE A O 1 ATOM 1096 C CB . PHE A 1 140 ? 8.236 9.806 19.515 1.00 2.53 ? 140 PHE A CB 1 ATOM 1097 C CG . PHE A 1 140 ? 6.935 9.389 20.096 1.00 3.16 ? 140 PHE A CG 1 ATOM 1098 C CD1 . PHE A 1 140 ? 6.783 9.244 21.471 1.00 3.08 ? 140 PHE A CD1 1 ATOM 1099 C CD2 . PHE A 1 140 ? 5.851 9.129 19.263 1.00 2.68 ? 140 PHE A CD2 1 ATOM 1100 C CE1 . PHE A 1 140 ? 5.571 8.849 22.009 1.00 2.44 ? 140 PHE A CE1 1 ATOM 1101 C CE2 . PHE A 1 140 ? 4.635 8.736 19.790 1.00 2.75 ? 140 PHE A CE2 1 ATOM 1102 C CZ . PHE A 1 140 ? 4.493 8.594 21.170 1.00 2.63 ? 140 PHE A CZ 1 ATOM 1103 N N . PRO A 1 141 ? 9.985 7.062 21.344 1.00 5.91 ? 141 PRO A N 1 ATOM 1104 C CA . PRO A 1 141 ? 10.085 5.584 21.582 1.00 2.71 ? 141 PRO A CA 1 ATOM 1105 C C . PRO A 1 141 ? 8.863 4.800 21.706 1.00 2.76 ? 141 PRO A C 1 ATOM 1106 O O . PRO A 1 141 ? 7.801 5.339 22.040 1.00 2.00 ? 141 PRO A O 1 ATOM 1107 C CB . PRO A 1 141 ? 10.914 5.469 22.820 1.00 3.07 ? 141 PRO A CB 1 ATOM 1108 C CG . PRO A 1 141 ? 11.929 6.562 22.613 1.00 3.95 ? 141 PRO A CG 1 ATOM 1109 C CD . PRO A 1 141 ? 11.323 7.583 21.683 1.00 4.96 ? 141 PRO A CD 1 ATOM 1110 N N . ILE A 1 142 ? 8.972 3.514 21.479 1.00 3.50 ? 142 ILE A N 1 ATOM 1111 C CA . ILE A 1 142 ? 7.844 2.733 21.815 1.00 3.10 ? 142 ILE A CA 1 ATOM 1112 C C . ILE A 1 142 ? 8.300 1.934 23.005 1.00 3.83 ? 142 ILE A C 1 ATOM 1113 O O . ILE A 1 142 ? 9.209 1.092 22.908 1.00 2.52 ? 142 ILE A O 1 ATOM 1114 C CB . ILE A 1 142 ? 7.394 1.763 20.741 1.00 2.39 ? 142 ILE A CB 1 ATOM 1115 C CG1 . ILE A 1 142 ? 7.099 2.507 19.438 1.00 2.90 ? 142 ILE A CG1 1 ATOM 1116 C CG2 . ILE A 1 142 ? 6.175 0.990 21.198 1.00 2.00 ? 142 ILE A CG2 1 ATOM 1117 C CD1 . ILE A 1 142 ? 6.560 1.633 18.325 1.00 3.76 ? 142 ILE A CD1 1 ATOM 1118 N N . MET A 1 143 ? 7.681 2.188 24.155 1.00 6.06 ? 143 MET A N 1 ATOM 1119 C CA . MET A 1 143 ? 8.065 1.503 25.380 1.00 8.04 ? 143 MET A CA 1 ATOM 1120 C C . MET A 1 143 ? 7.439 0.118 25.502 1.00 8.11 ? 143 MET A C 1 ATOM 1121 O O . MET A 1 143 ? 6.349 -0.127 24.994 1.00 7.05 ? 143 MET A O 1 ATOM 1122 C CB . MET A 1 143 ? 7.662 2.359 26.587 1.00 11.12 ? 143 MET A CB 1 ATOM 1123 C CG . MET A 1 143 ? 8.797 2.669 27.555 1.00 15.03 ? 143 MET A CG 1 ATOM 1124 S SD . MET A 1 143 ? 10.175 3.506 26.755 1.00 18.64 ? 143 MET A SD 1 ATOM 1125 C CE . MET A 1 143 ? 10.651 4.668 28.033 1.00 19.38 ? 143 MET A CE 1 ATOM 1126 N N . PHE A 1 144 ? 8.146 -0.786 26.173 1.00 9.23 ? 144 PHE A N 1 ATOM 1127 C CA . PHE A 1 144 ? 7.656 -2.113 26.434 1.00 10.59 ? 144 PHE A CA 1 ATOM 1128 C C . PHE A 1 144 ? 6.917 -2.142 27.788 1.00 11.43 ? 144 PHE A C 1 ATOM 1129 O O . PHE A 1 144 ? 7.443 -1.697 28.807 1.00 12.89 ? 144 PHE A O 1 ATOM 1130 C CB . PHE A 1 144 ? 8.812 -3.139 26.524 1.00 12.03 ? 144 PHE A CB 1 ATOM 1131 C CG . PHE A 1 144 ? 9.533 -3.400 25.242 1.00 13.89 ? 144 PHE A CG 1 ATOM 1132 C CD1 . PHE A 1 144 ? 10.907 -3.588 25.238 1.00 14.62 ? 144 PHE A CD1 1 ATOM 1133 C CD2 . PHE A 1 144 ? 8.843 -3.472 24.040 1.00 15.35 ? 144 PHE A CD2 1 ATOM 1134 C CE1 . PHE A 1 144 ? 11.588 -3.841 24.056 1.00 16.66 ? 144 PHE A CE1 1 ATOM 1135 C CE2 . PHE A 1 144 ? 9.512 -3.726 22.848 1.00 17.21 ? 144 PHE A CE2 1 ATOM 1136 C CZ . PHE A 1 144 ? 10.889 -3.910 22.855 1.00 17.71 ? 144 PHE A CZ 1 ATOM 1137 N N . PRO A 1 145 ? 5.717 -2.668 27.767 1.00 12.54 ? 145 PRO A N 1 ATOM 1138 C CA . PRO A 1 145 ? 4.944 -2.853 28.999 1.00 15.33 ? 145 PRO A CA 1 ATOM 1139 C C . PRO A 1 145 ? 5.679 -3.760 29.975 1.00 16.36 ? 145 PRO A C 1 ATOM 1140 O O . PRO A 1 145 ? 6.729 -4.304 29.641 1.00 17.90 ? 145 PRO A O 1 ATOM 1141 C CB . PRO A 1 145 ? 3.585 -3.293 28.477 1.00 13.96 ? 145 PRO A CB 1 ATOM 1142 C CG . PRO A 1 145 ? 3.448 -2.469 27.234 1.00 13.49 ? 145 PRO A CG 1 ATOM 1143 C CD . PRO A 1 145 ? 4.808 -2.092 26.771 1.00 12.69 ? 145 PRO A CD 1 ATOM 1144 N N . LYS A 1 146 ? 5.121 -3.922 31.154 1.00 17.40 ? 146 LYS A N 1 ATOM 1145 C CA . LYS A 1 146 ? 5.670 -4.839 32.145 1.00 18.84 ? 146 LYS A CA 1 ATOM 1146 C C . LYS A 1 146 ? 5.309 -6.268 31.724 1.00 17.65 ? 146 LYS A C 1 ATOM 1147 O O . LYS A 1 146 ? 4.296 -6.467 31.048 1.00 15.09 ? 146 LYS A O 1 ATOM 1148 C CB . LYS A 1 146 ? 5.132 -4.544 33.544 1.00 20.72 ? 146 LYS A CB 1 ATOM 1149 C CG . LYS A 1 146 ? 4.951 -5.773 34.428 1.00 22.40 ? 146 LYS A CG 1 ATOM 1150 C CD . LYS A 1 146 ? 4.054 -5.497 35.617 1.00 24.81 ? 146 LYS A CD 1 ATOM 1151 C CE . LYS A 1 146 ? 3.640 -6.799 36.281 1.00 26.02 ? 146 LYS A CE 1 ATOM 1152 N NZ . LYS A 1 146 ? 2.602 -6.582 37.340 1.00 27.45 ? 146 LYS A NZ 1 ATOM 1153 N N . ASN A 1 147 ? 6.117 -7.233 32.106 1.00 17.37 ? 147 ASN A N 1 ATOM 1154 C CA . ASN A 1 147 ? 5.802 -8.620 31.820 1.00 18.19 ? 147 ASN A CA 1 ATOM 1155 C C . ASN A 1 147 ? 5.626 -8.942 30.347 1.00 16.11 ? 147 ASN A C 1 ATOM 1156 O O . ASN A 1 147 ? 4.780 -9.766 29.985 1.00 16.37 ? 147 ASN A O 1 ATOM 1157 C CB . ASN A 1 147 ? 4.569 -9.032 32.613 1.00 21.26 ? 147 ASN A CB 1 ATOM 1158 C CG . ASN A 1 147 ? 4.915 -9.455 34.030 1.00 23.29 ? 147 ASN A CG 1 ATOM 1159 O OD1 . ASN A 1 147 ? 4.051 -9.486 34.902 1.00 23.36 ? 147 ASN A OD1 1 ATOM 1160 N ND2 . ASN A 1 147 ? 6.197 -9.768 34.257 1.00 23.13 ? 147 ASN A ND2 1 ATOM 1161 N N . ASP A 1 148 ? 6.456 -8.292 29.501 1.00 12.32 ? 148 ASP A N 1 ATOM 1162 C CA . ASP A 1 148 ? 6.427 -8.455 28.027 1.00 7.15 ? 148 ASP A CA 1 ATOM 1163 C C . ASP A 1 148 ? 7.718 -9.160 27.491 1.00 5.76 ? 148 ASP A C 1 ATOM 1164 O O . ASP A 1 148 ? 8.827 -8.838 27.930 1.00 6.15 ? 148 ASP A O 1 ATOM 1165 C CB . ASP A 1 148 ? 6.247 -7.121 27.344 1.00 7.55 ? 148 ASP A CB 1 ATOM 1166 C CG . ASP A 1 148 ? 6.415 -7.280 25.839 1.00 6.98 ? 148 ASP A CG 1 ATOM 1167 O OD1 . ASP A 1 148 ? 7.446 -7.806 25.385 1.00 6.93 ? 148 ASP A OD1 1 ATOM 1168 O OD2 . ASP A 1 148 ? 5.489 -6.866 25.100 1.00 4.15 ? 148 ASP A OD2 1 ATOM 1169 N N . PRO A 1 149 ? 7.577 -10.130 26.542 1.00 4.00 ? 149 PRO A N 1 ATOM 1170 C CA . PRO A 1 149 ? 8.772 -11.002 26.147 1.00 3.31 ? 149 PRO A CA 1 ATOM 1171 C C . PRO A 1 149 ? 9.992 -10.297 25.715 1.00 2.77 ? 149 PRO A C 1 ATOM 1172 O O . PRO A 1 149 ? 11.112 -10.610 26.094 1.00 5.15 ? 149 PRO A O 1 ATOM 1173 C CB . PRO A 1 149 ? 8.252 -11.932 25.076 1.00 2.27 ? 149 PRO A CB 1 ATOM 1174 C CG . PRO A 1 149 ? 6.908 -12.241 25.625 1.00 3.58 ? 149 PRO A CG 1 ATOM 1175 C CD . PRO A 1 149 ? 6.473 -11.110 26.535 1.00 3.40 ? 149 PRO A CD 1 ATOM 1176 N N . LYS A 1 150 ? 9.687 -9.316 24.901 1.00 2.00 ? 150 LYS A N 1 ATOM 1177 C CA . LYS A 1 150 ? 10.693 -8.506 24.275 1.00 2.98 ? 150 LYS A CA 1 ATOM 1178 C C . LYS A 1 150 ? 11.624 -7.872 25.274 1.00 2.01 ? 150 LYS A C 1 ATOM 1179 O O . LYS A 1 150 ? 12.732 -7.497 24.934 1.00 2.00 ? 150 LYS A O 1 ATOM 1180 C CB . LYS A 1 150 ? 10.037 -7.451 23.371 1.00 3.41 ? 150 LYS A CB 1 ATOM 1181 C CG . LYS A 1 150 ? 9.180 -8.042 22.267 1.00 4.59 ? 150 LYS A CG 1 ATOM 1182 C CD . LYS A 1 150 ? 9.626 -7.576 20.894 1.00 4.71 ? 150 LYS A CD 1 ATOM 1183 C CE . LYS A 1 150 ? 9.002 -8.424 19.806 1.00 3.90 ? 150 LYS A CE 1 ATOM 1184 N NZ . LYS A 1 150 ? 9.417 -9.849 19.905 1.00 4.73 ? 150 LYS A NZ 1 ATOM 1185 N N . LEU A 1 151 ? 11.164 -7.755 26.496 1.00 2.50 ? 151 LEU A N 1 ATOM 1186 C CA . LEU A 1 151 ? 11.960 -7.182 27.601 1.00 2.00 ? 151 LEU A CA 1 ATOM 1187 C C . LEU A 1 151 ? 13.196 -8.021 27.907 1.00 2.83 ? 151 LEU A C 1 ATOM 1188 O O . LEU A 1 151 ? 14.329 -7.526 27.912 1.00 2.00 ? 151 LEU A O 1 ATOM 1189 C CB . LEU A 1 151 ? 11.095 -7.118 28.861 1.00 2.00 ? 151 LEU A CB 1 ATOM 1190 C CG . LEU A 1 151 ? 11.045 -5.786 29.628 1.00 2.00 ? 151 LEU A CG 1 ATOM 1191 C CD1 . LEU A 1 151 ? 9.604 -5.343 29.866 1.00 2.85 ? 151 LEU A CD1 1 ATOM 1192 C CD2 . LEU A 1 151 ? 11.799 -5.907 30.940 1.00 3.85 ? 151 LEU A CD2 1 ATOM 1193 N N . LYS A 1 152 ? 12.967 -9.302 28.163 1.00 3.30 ? 152 LYS A N 1 ATOM 1194 C CA . LYS A 1 152 ? 14.055 -10.213 28.466 1.00 3.10 ? 152 LYS A CA 1 ATOM 1195 C C . LYS A 1 152 ? 15.053 -10.261 27.309 1.00 5.32 ? 152 LYS A C 1 ATOM 1196 O O . LYS A 1 152 ? 16.265 -10.420 27.544 1.00 5.50 ? 152 LYS A O 1 ATOM 1197 C CB . LYS A 1 152 ? 13.495 -11.608 28.816 1.00 2.42 ? 152 LYS A CB 1 ATOM 1198 C CG . LYS A 1 152 ? 12.305 -11.580 29.753 1.00 3.52 ? 152 LYS A CG 1 ATOM 1199 C CD . LYS A 1 152 ? 11.981 -12.960 30.326 1.00 3.46 ? 152 LYS A CD 1 ATOM 1200 C CE . LYS A 1 152 ? 11.012 -12.862 31.495 1.00 3.71 ? 152 LYS A CE 1 ATOM 1201 N NZ . LYS A 1 152 ? 10.399 -14.176 31.828 1.00 4.09 ? 152 LYS A NZ 1 ATOM 1202 N N . THR A 1 153 ? 14.491 -10.156 26.069 1.00 4.99 ? 153 THR A N 1 ATOM 1203 C CA . THR A 1 153 ? 15.231 -10.366 24.795 1.00 3.05 ? 153 THR A CA 1 ATOM 1204 C C . THR A 1 153 ? 15.742 -9.199 23.949 1.00 4.45 ? 153 THR A C 1 ATOM 1205 O O . THR A 1 153 ? 16.778 -9.362 23.319 1.00 4.64 ? 153 THR A O 1 ATOM 1206 C CB . THR A 1 153 ? 14.357 -11.281 23.908 1.00 2.00 ? 153 THR A CB 1 ATOM 1207 O OG1 . THR A 1 153 ? 14.197 -12.536 24.561 1.00 2.00 ? 153 THR A OG1 1 ATOM 1208 C CG2 . THR A 1 153 ? 15.000 -11.482 22.552 1.00 2.35 ? 153 THR A CG2 1 ATOM 1209 N N . GLN A 1 154 ? 15.087 -8.072 23.912 1.00 4.79 ? 154 GLN A N 1 ATOM 1210 C CA . GLN A 1 154 ? 15.597 -7.077 22.967 1.00 4.28 ? 154 GLN A CA 1 ATOM 1211 C C . GLN A 1 154 ? 16.001 -5.904 23.793 1.00 3.43 ? 154 GLN A C 1 ATOM 1212 O O . GLN A 1 154 ? 17.064 -5.327 23.622 1.00 2.83 ? 154 GLN A O 1 ATOM 1213 C CB . GLN A 1 154 ? 14.569 -6.657 21.948 1.00 4.27 ? 154 GLN A CB 1 ATOM 1214 C CG . GLN A 1 154 ? 14.739 -7.253 20.581 1.00 2.00 ? 154 GLN A CG 1 ATOM 1215 C CD . GLN A 1 154 ? 13.479 -7.053 19.781 1.00 2.00 ? 154 GLN A CD 1 ATOM 1216 O OE1 . GLN A 1 154 ? 12.462 -7.707 20.009 1.00 2.00 ? 154 GLN A OE1 1 ATOM 1217 N NE2 . GLN A 1 154 ? 13.321 -6.188 18.780 1.00 2.39 ? 154 GLN A NE2 1 ATOM 1218 N N . GLY A 1 155 ? 15.124 -5.550 24.718 1.00 3.15 ? 155 GLY A N 1 ATOM 1219 C CA . GLY A 1 155 ? 15.492 -4.406 25.527 1.00 5.18 ? 155 GLY A CA 1 ATOM 1220 C C . GLY A 1 155 ? 14.371 -3.672 26.270 1.00 8.16 ? 155 GLY A C 1 ATOM 1221 O O . GLY A 1 155 ? 13.475 -4.269 26.841 1.00 8.13 ? 155 GLY A O 1 ATOM 1222 N N . LYS A 1 156 ? 14.471 -2.349 26.229 1.00 9.97 ? 156 LYS A N 1 ATOM 1223 C CA . LYS A 1 156 ? 13.535 -1.478 26.921 1.00 11.09 ? 156 LYS A CA 1 ATOM 1224 C C . LYS A 1 156 ? 12.467 -0.915 26.001 1.00 11.36 ? 156 LYS A C 1 ATOM 1225 O O . LYS A 1 156 ? 11.326 -0.708 26.409 1.00 11.47 ? 156 LYS A O 1 ATOM 1226 C CB . LYS A 1 156 ? 14.304 -0.320 27.563 1.00 12.85 ? 156 LYS A CB 1 ATOM 1227 C CG . LYS A 1 156 ? 14.158 -0.230 29.073 1.00 16.07 ? 156 LYS A CG 1 ATOM 1228 C CD . LYS A 1 156 ? 15.121 0.794 29.670 1.00 19.00 ? 156 LYS A CD 1 ATOM 1229 C CE . LYS A 1 156 ? 14.977 0.856 31.185 1.00 20.60 ? 156 LYS A CE 1 ATOM 1230 N NZ . LYS A 1 156 ? 14.932 -0.498 31.798 1.00 22.74 ? 156 LYS A NZ 1 ATOM 1231 N N . CYS A 1 157 ? 12.836 -0.686 24.779 1.00 9.27 ? 157 CYS A N 1 ATOM 1232 C CA . CYS A 1 157 ? 11.944 -0.128 23.815 1.00 7.89 ? 157 CYS A CA 1 ATOM 1233 C C . CYS A 1 157 ? 12.482 -0.356 22.414 1.00 9.17 ? 157 CYS A C 1 ATOM 1234 O O . CYS A 1 157 ? 13.641 -0.774 22.243 1.00 10.42 ? 157 CYS A O 1 ATOM 1235 C CB . CYS A 1 157 ? 11.828 1.369 24.026 1.00 8.79 ? 157 CYS A CB 1 ATOM 1236 S SG . CYS A 1 157 ? 13.236 2.319 23.364 1.00 9.13 ? 157 CYS A SG 1 ATOM 1237 N N . MET A 1 158 ? 11.640 -0.079 21.433 1.00 8.05 ? 158 MET A N 1 ATOM 1238 C CA . MET A 1 158 ? 12.094 -0.188 20.063 1.00 5.37 ? 158 MET A CA 1 ATOM 1239 C C . MET A 1 158 ? 12.005 1.172 19.383 1.00 4.67 ? 158 MET A C 1 ATOM 1240 O O . MET A 1 158 ? 11.043 1.903 19.529 1.00 3.27 ? 158 MET A O 1 ATOM 1241 C CB . MET A 1 158 ? 11.294 -1.211 19.296 1.00 5.41 ? 158 MET A CB 1 ATOM 1242 C CG . MET A 1 158 ? 9.817 -1.091 19.526 1.00 4.75 ? 158 MET A CG 1 ATOM 1243 S SD . MET A 1 158 ? 8.897 -2.374 18.670 1.00 7.14 ? 158 MET A SD 1 ATOM 1244 C CE . MET A 1 158 ? 9.248 -3.789 19.707 1.00 5.28 ? 158 MET A CE 1 ATOM 1245 N N . PRO A 1 159 ? 13.070 1.471 18.610 1.00 3.10 ? 159 PRO A N 1 ATOM 1246 C CA . PRO A 1 159 ? 13.169 2.815 17.919 1.00 3.50 ? 159 PRO A CA 1 ATOM 1247 C C . PRO A 1 159 ? 11.951 3.298 17.152 1.00 4.40 ? 159 PRO A C 1 ATOM 1248 O O . PRO A 1 159 ? 11.205 2.498 16.572 1.00 4.70 ? 159 PRO A O 1 ATOM 1249 C CB . PRO A 1 159 ? 14.470 2.716 17.155 1.00 3.96 ? 159 PRO A CB 1 ATOM 1250 C CG . PRO A 1 159 ? 15.317 1.970 18.135 1.00 4.72 ? 159 PRO A CG 1 ATOM 1251 C CD . PRO A 1 159 ? 14.447 1.110 19.010 1.00 4.05 ? 159 PRO A CD 1 ATOM 1252 N N . PHE A 1 160 ? 11.728 4.590 17.128 1.00 4.55 ? 160 PHE A N 1 ATOM 1253 C CA . PHE A 1 160 ? 10.612 5.130 16.378 1.00 4.64 ? 160 PHE A CA 1 ATOM 1254 C C . PHE A 1 160 ? 10.813 6.620 16.224 1.00 5.09 ? 160 PHE A C 1 ATOM 1255 O O . PHE A 1 160 ? 10.830 7.361 17.208 1.00 4.33 ? 160 PHE A O 1 ATOM 1256 C CB . PHE A 1 160 ? 9.280 4.857 17.087 1.00 4.55 ? 160 PHE A CB 1 ATOM 1257 C CG . PHE A 1 160 ? 8.111 5.347 16.273 1.00 3.53 ? 160 PHE A CG 1 ATOM 1258 C CD1 . PHE A 1 160 ? 7.794 6.697 16.252 1.00 3.03 ? 160 PHE A CD1 1 ATOM 1259 C CD2 . PHE A 1 160 ? 7.356 4.463 15.517 1.00 2.32 ? 160 PHE A CD2 1 ATOM 1260 C CE1 . PHE A 1 160 ? 6.744 7.161 15.491 1.00 4.54 ? 160 PHE A CE1 1 ATOM 1261 C CE2 . PHE A 1 160 ? 6.307 4.911 14.754 1.00 3.84 ? 160 PHE A CE2 1 ATOM 1262 C CZ . PHE A 1 160 ? 5.995 6.268 14.737 1.00 4.97 ? 160 PHE A CZ 1 ATOM 1263 N N . PHE A 1 161 ? 10.963 7.047 14.976 1.00 7.01 ? 161 PHE A N 1 ATOM 1264 C CA . PHE A 1 161 ? 11.171 8.454 14.661 1.00 8.25 ? 161 PHE A CA 1 ATOM 1265 C C . PHE A 1 161 ? 9.942 9.058 14.002 1.00 8.09 ? 161 PHE A C 1 ATOM 1266 O O . PHE A 1 161 ? 9.435 8.533 13.016 1.00 8.63 ? 161 PHE A O 1 ATOM 1267 C CB . PHE A 1 161 ? 12.358 8.613 13.720 1.00 9.25 ? 161 PHE A CB 1 ATOM 1268 C CG . PHE A 1 161 ? 13.656 8.176 14.306 1.00 9.67 ? 161 PHE A CG 1 ATOM 1269 C CD1 . PHE A 1 161 ? 13.878 6.843 14.625 1.00 10.72 ? 161 PHE A CD1 1 ATOM 1270 C CD2 . PHE A 1 161 ? 14.656 9.101 14.550 1.00 10.32 ? 161 PHE A CD2 1 ATOM 1271 C CE1 . PHE A 1 161 ? 15.083 6.438 15.180 1.00 10.80 ? 161 PHE A CE1 1 ATOM 1272 C CE2 . PHE A 1 161 ? 15.863 8.709 15.105 1.00 11.22 ? 161 PHE A CE2 1 ATOM 1273 C CZ . PHE A 1 161 ? 16.078 7.376 15.421 1.00 11.61 ? 161 PHE A CZ 1 ATOM 1274 N N . ARG A 1 162 ? 9.479 10.176 14.540 1.00 8.35 ? 162 ARG A N 1 ATOM 1275 C CA . ARG A 1 162 ? 8.306 10.850 14.003 1.00 8.53 ? 162 ARG A CA 1 ATOM 1276 C C . ARG A 1 162 ? 8.483 11.114 12.519 1.00 6.84 ? 162 ARG A C 1 ATOM 1277 O O . ARG A 1 162 ? 9.610 11.200 12.041 1.00 6.30 ? 162 ARG A O 1 ATOM 1278 C CB . ARG A 1 162 ? 8.072 12.153 14.744 1.00 7.61 ? 162 ARG A CB 1 ATOM 1279 C CG . ARG A 1 162 ? 8.439 12.059 16.200 1.00 5.53 ? 162 ARG A CG 1 ATOM 1280 C CD . ARG A 1 162 ? 8.007 13.319 16.910 1.00 5.46 ? 162 ARG A CD 1 ATOM 1281 N NE . ARG A 1 162 ? 6.693 13.766 16.489 1.00 5.04 ? 162 ARG A NE 1 ATOM 1282 C CZ . ARG A 1 162 ? 6.203 14.972 16.816 1.00 5.24 ? 162 ARG A CZ 1 ATOM 1283 N NH1 . ARG A 1 162 ? 6.928 15.820 17.536 1.00 5.93 ? 162 ARG A NH1 1 ATOM 1284 N NH2 . ARG A 1 162 ? 4.983 15.316 16.408 1.00 6.21 ? 162 ARG A NH2 1 ATOM 1285 N N . ALA A 1 163 ? 7.373 11.254 11.798 1.00 6.28 ? 163 ALA A N 1 ATOM 1286 C CA . ALA A 1 163 ? 7.434 11.473 10.355 1.00 5.95 ? 163 ALA A CA 1 ATOM 1287 C C . ALA A 1 163 ? 7.564 12.926 9.930 1.00 5.74 ? 163 ALA A C 1 ATOM 1288 O O . ALA A 1 163 ? 7.071 13.829 10.608 1.00 5.55 ? 163 ALA A O 1 ATOM 1289 C CB . ALA A 1 163 ? 6.225 10.845 9.690 1.00 6.98 ? 163 ALA A CB 1 ATOM 1290 N N . GLY A 1 164 ? 8.205 13.127 8.789 1.00 5.31 ? 164 GLY A N 1 ATOM 1291 C CA . GLY A 1 164 ? 8.504 14.426 8.253 1.00 6.41 ? 164 GLY A CA 1 ATOM 1292 C C . GLY A 1 164 ? 7.323 15.382 8.114 1.00 7.72 ? 164 GLY A C 1 ATOM 1293 O O . GLY A 1 164 ? 6.225 15.020 7.709 1.00 7.58 ? 164 GLY A O 1 ATOM 1294 N N . PHE A 1 165 ? 7.645 16.635 8.472 1.00 9.10 ? 165 PHE A N 1 ATOM 1295 C CA . PHE A 1 165 ? 6.741 17.770 8.398 1.00 11.64 ? 165 PHE A CA 1 ATOM 1296 C C . PHE A 1 165 ? 7.410 18.885 7.597 1.00 14.88 ? 165 PHE A C 1 ATOM 1297 O O . PHE A 1 165 ? 8.618 19.081 7.536 1.00 15.33 ? 165 PHE A O 1 ATOM 1298 C CB . PHE A 1 165 ? 6.260 18.227 9.757 1.00 11.87 ? 165 PHE A CB 1 ATOM 1299 C CG . PHE A 1 165 ? 7.454 18.518 10.569 1.00 12.89 ? 165 PHE A CG 1 ATOM 1300 C CD1 . PHE A 1 165 ? 8.207 17.475 11.115 1.00 13.50 ? 165 PHE A CD1 1 ATOM 1301 C CD2 . PHE A 1 165 ? 7.868 19.832 10.758 1.00 12.24 ? 165 PHE A CD2 1 ATOM 1302 C CE1 . PHE A 1 165 ? 9.346 17.739 11.839 1.00 13.55 ? 165 PHE A CE1 1 ATOM 1303 C CE2 . PHE A 1 165 ? 9.003 20.109 11.480 1.00 12.44 ? 165 PHE A CE2 1 ATOM 1304 C CZ . PHE A 1 165 ? 9.744 19.064 12.024 1.00 13.90 ? 165 PHE A CZ 1 ATOM 1305 N N . VAL A 1 166 ? 6.453 19.583 6.997 1.00 17.69 ? 166 VAL A N 1 ATOM 1306 C CA . VAL A 1 166 ? 6.447 20.635 5.969 1.00 21.39 ? 166 VAL A CA 1 ATOM 1307 C C . VAL A 1 166 ? 7.008 21.999 5.983 1.00 26.49 ? 166 VAL A C 1 ATOM 1308 O O . VAL A 1 166 ? 6.658 22.711 5.033 1.00 25.99 ? 166 VAL A O 1 ATOM 1309 C CB . VAL A 1 166 ? 4.991 20.944 5.583 1.00 20.08 ? 166 VAL A CB 1 ATOM 1310 C CG1 . VAL A 1 166 ? 4.359 19.772 4.852 1.00 19.42 ? 166 VAL A CG1 1 ATOM 1311 C CG2 . VAL A 1 166 ? 4.163 21.284 6.813 1.00 21.41 ? 166 VAL A CG2 1 ATOM 1312 N N . CYS A 1 167 ? 7.762 22.522 6.843 1.00 33.14 ? 167 CYS A N 1 ATOM 1313 C CA . CYS A 1 167 ? 8.252 23.827 6.397 1.00 38.51 ? 167 CYS A CA 1 ATOM 1314 C C . CYS A 1 167 ? 9.730 23.533 6.391 1.00 38.60 ? 167 CYS A C 1 ATOM 1315 O O . CYS A 1 167 ? 10.510 23.731 5.449 1.00 39.84 ? 167 CYS A O 1 ATOM 1316 C CB . CYS A 1 167 ? 7.773 24.968 7.286 1.00 45.40 ? 167 CYS A CB 1 ATOM 1317 S SG . CYS A 1 167 ? 5.971 25.243 7.257 1.00 55.95 ? 167 CYS A SG 1 ATOM 1318 N N . PRO A 1 168 ? 10.007 23.038 7.597 1.00 38.32 ? 168 PRO A N 1 ATOM 1319 C CA . PRO A 1 168 ? 11.340 22.438 7.999 1.00 38.08 ? 168 PRO A CA 1 ATOM 1320 C C . PRO A 1 168 ? 11.744 21.066 7.397 1.00 40.32 ? 168 PRO A C 1 ATOM 1321 O O . PRO A 1 168 ? 11.520 20.740 6.236 1.00 38.44 ? 168 PRO A O 1 ATOM 1322 C CB . PRO A 1 168 ? 11.266 22.520 9.519 1.00 37.46 ? 168 PRO A CB 1 ATOM 1323 C CG . PRO A 1 168 ? 10.557 23.785 9.768 1.00 38.21 ? 168 PRO A CG 1 ATOM 1324 C CD . PRO A 1 168 ? 9.738 24.132 8.571 1.00 37.81 ? 168 PRO A CD 1 ATOM 1325 N N . THR A 1 169 ? 12.354 20.309 8.320 1.00 42.83 ? 169 THR A N 1 ATOM 1326 C CA . THR A 1 169 ? 12.854 18.973 8.386 1.00 46.43 ? 169 THR A CA 1 ATOM 1327 C C . THR A 1 169 ? 13.299 19.038 9.910 1.00 48.82 ? 169 THR A C 1 ATOM 1328 O O . THR A 1 169 ? 12.741 18.353 10.770 1.00 50.45 ? 169 THR A O 1 ATOM 1329 C CB . THR A 1 169 ? 13.946 18.613 7.335 1.00 48.50 ? 169 THR A CB 1 ATOM 1330 O OG1 . THR A 1 169 ? 14.023 19.640 6.346 1.00 50.05 ? 169 THR A OG1 1 ATOM 1331 C CG2 . THR A 1 169 ? 13.609 17.278 6.664 1.00 49.13 ? 169 THR A CG2 1 ATOM 1332 N N . PRO A 1 170 ? 14.364 19.851 10.132 1.00 50.53 ? 170 PRO A N 1 ATOM 1333 C CA . PRO A 1 170 ? 14.838 20.190 11.490 1.00 50.91 ? 170 PRO A CA 1 ATOM 1334 C C . PRO A 1 170 ? 13.736 20.765 12.354 1.00 51.40 ? 170 PRO A C 1 ATOM 1335 O O . PRO A 1 170 ? 12.554 20.724 12.009 1.00 50.51 ? 170 PRO A O 1 ATOM 1336 C CB . PRO A 1 170 ? 16.098 20.989 11.256 1.00 50.77 ? 170 PRO A CB 1 ATOM 1337 C CG . PRO A 1 170 ? 16.661 20.269 10.078 1.00 49.82 ? 170 PRO A CG 1 ATOM 1338 C CD . PRO A 1 170 ? 15.544 19.596 9.328 1.00 49.53 ? 170 PRO A CD 1 ATOM 1339 N N . PRO A 1 171 ? 14.180 21.346 13.475 1.00 52.57 ? 171 PRO A N 1 ATOM 1340 C CA . PRO A 1 171 ? 13.314 21.878 14.635 1.00 53.34 ? 171 PRO A CA 1 ATOM 1341 C C . PRO A 1 171 ? 12.204 23.043 14.868 1.00 54.05 ? 171 PRO A C 1 ATOM 1342 O O . PRO A 1 171 ? 12.503 23.660 15.883 1.00 52.71 ? 171 PRO A O 1 ATOM 1343 C CB . PRO A 1 171 ? 14.382 22.108 15.676 1.00 53.57 ? 171 PRO A CB 1 ATOM 1344 C CG . PRO A 1 171 ? 15.354 20.998 15.485 1.00 53.20 ? 171 PRO A CG 1 ATOM 1345 C CD . PRO A 1 171 ? 15.255 20.534 14.055 1.00 52.80 ? 171 PRO A CD 1 ATOM 1346 N N . TYR A 1 172 ? 11.028 23.557 14.317 1.00 55.88 ? 172 TYR A N 1 ATOM 1347 C CA . TYR A 1 172 ? 10.510 24.836 15.092 1.00 57.00 ? 172 TYR A CA 1 ATOM 1348 C C . TYR A 1 172 ? 8.981 25.195 15.456 1.00 55.72 ? 172 TYR A C 1 ATOM 1349 O O . TYR A 1 172 ? 8.489 24.718 16.478 1.00 55.54 ? 172 TYR A O 1 ATOM 1350 C CB . TYR A 1 172 ? 10.759 26.179 14.367 1.00 61.89 ? 172 TYR A CB 1 ATOM 1351 C CG . TYR A 1 172 ? 11.996 27.040 14.171 1.00 66.36 ? 172 TYR A CG 1 ATOM 1352 C CD1 . TYR A 1 172 ? 13.207 27.031 14.867 1.00 67.34 ? 172 TYR A CD1 1 ATOM 1353 C CD2 . TYR A 1 172 ? 11.828 27.973 13.170 1.00 67.67 ? 172 TYR A CD2 1 ATOM 1354 C CE1 . TYR A 1 172 ? 14.238 27.850 14.452 1.00 69.16 ? 172 TYR A CE1 1 ATOM 1355 C CE2 . TYR A 1 172 ? 12.861 28.806 12.757 1.00 69.14 ? 172 TYR A CE2 1 ATOM 1356 C CZ . TYR A 1 172 ? 14.056 28.720 13.377 1.00 69.43 ? 172 TYR A CZ 1 ATOM 1357 O OH . TYR A 1 172 ? 15.116 29.481 12.926 1.00 70.32 ? 172 TYR A OH 1 ATOM 1358 N N . GLN A 1 173 ? 8.144 26.058 14.685 1.00 52.73 ? 173 GLN A N 1 ATOM 1359 C CA . GLN A 1 173 ? 6.837 26.614 15.352 1.00 49.61 ? 173 GLN A CA 1 ATOM 1360 C C . GLN A 1 173 ? 5.330 26.846 14.765 1.00 46.43 ? 173 GLN A C 1 ATOM 1361 O O . GLN A 1 173 ? 4.762 25.990 14.088 1.00 46.00 ? 173 GLN A O 1 ATOM 1362 C CB . GLN A 1 173 ? 7.313 27.950 15.922 1.00 50.11 ? 173 GLN A CB 1 ATOM 1363 C CG . GLN A 1 173 ? 8.592 28.454 15.234 1.00 50.76 ? 173 GLN A CG 1 ATOM 1364 C CD . GLN A 1 173 ? 9.304 29.599 15.946 1.00 51.64 ? 173 GLN A CD 1 ATOM 1365 O OE1 . GLN A 1 173 ? 9.595 29.525 17.146 1.00 51.82 ? 173 GLN A OE1 1 ATOM 1366 N NE2 . GLN A 1 173 ? 9.682 30.755 15.395 1.00 51.11 ? 173 GLN A NE2 1 ATOM 1367 N N . SER A 1 174 ? 4.760 28.073 15.135 1.00 42.94 ? 174 SER A N 1 ATOM 1368 C CA . SER A 1 174 ? 3.419 28.658 14.943 1.00 38.46 ? 174 SER A CA 1 ATOM 1369 C C . SER A 1 174 ? 2.207 27.706 14.461 1.00 34.47 ? 174 SER A C 1 ATOM 1370 O O . SER A 1 174 ? 1.209 27.750 15.180 1.00 33.16 ? 174 SER A O 1 ATOM 1371 C CB . SER A 1 174 ? 3.666 29.963 14.176 1.00 39.12 ? 174 SER A CB 1 ATOM 1372 O OG . SER A 1 174 ? 2.935 29.993 12.963 1.00 39.92 ? 174 SER A OG 1 ATOM 1373 N N . LEU A 1 175 ? 2.172 26.879 13.359 1.00 28.92 ? 175 LEU A N 1 ATOM 1374 C CA . LEU A 1 175 ? 0.898 26.192 12.957 1.00 21.71 ? 175 LEU A CA 1 ATOM 1375 C C . LEU A 1 175 ? 0.751 24.641 13.078 1.00 17.66 ? 175 LEU A C 1 ATOM 1376 O O . LEU A 1 175 ? 1.749 23.910 12.988 1.00 17.36 ? 175 LEU A O 1 ATOM 1377 C CB . LEU A 1 175 ? 0.608 26.562 11.496 1.00 20.57 ? 175 LEU A CB 1 ATOM 1378 C CG . LEU A 1 175 ? -0.877 26.620 11.092 1.00 19.97 ? 175 LEU A CG 1 ATOM 1379 C CD1 . LEU A 1 175 ? -1.014 27.267 9.719 1.00 18.80 ? 175 LEU A CD1 1 ATOM 1380 C CD2 . LEU A 1 175 ? -1.504 25.221 11.112 1.00 17.90 ? 175 LEU A CD2 1 ATOM 1381 N N . ALA A 1 176 ? -0.481 24.175 13.286 1.00 12.89 ? 176 ALA A N 1 ATOM 1382 C CA . ALA A 1 176 ? -0.725 22.780 13.449 1.00 8.97 ? 176 ALA A CA 1 ATOM 1383 C C . ALA A 1 176 ? 0.081 22.047 12.406 1.00 6.31 ? 176 ALA A C 1 ATOM 1384 O O . ALA A 1 176 ? -0.067 22.267 11.211 1.00 4.19 ? 176 ALA A O 1 ATOM 1385 C CB . ALA A 1 176 ? -2.211 22.451 13.303 1.00 9.22 ? 176 ALA A CB 1 ATOM 1386 N N . ARG A 1 177 ? 0.928 21.170 12.887 1.00 2.59 ? 177 ARG A N 1 ATOM 1387 C CA . ARG A 1 177 ? 1.843 20.313 12.126 1.00 2.00 ? 177 ARG A CA 1 ATOM 1388 C C . ARG A 1 177 ? 1.216 19.352 11.110 1.00 2.00 ? 177 ARG A C 1 ATOM 1389 O O . ARG A 1 177 ? 0.226 18.678 11.423 1.00 2.41 ? 177 ARG A O 1 ATOM 1390 C CB . ARG A 1 177 ? 2.659 19.502 13.143 1.00 2.78 ? 177 ARG A CB 1 ATOM 1391 C CG . ARG A 1 177 ? 3.607 18.475 12.558 1.00 2.00 ? 177 ARG A CG 1 ATOM 1392 C CD . ARG A 1 177 ? 5.035 18.834 12.904 1.00 2.04 ? 177 ARG A CD 1 ATOM 1393 N NE . ARG A 1 177 ? 5.801 17.769 13.535 1.00 2.18 ? 177 ARG A NE 1 ATOM 1394 C CZ . ARG A 1 177 ? 7.000 17.951 14.083 1.00 4.00 ? 177 ARG A CZ 1 ATOM 1395 N NH1 . ARG A 1 177 ? 7.560 19.158 14.075 1.00 3.44 ? 177 ARG A NH1 1 ATOM 1396 N NH2 . ARG A 1 177 ? 7.642 16.932 14.640 1.00 4.80 ? 177 ARG A NH2 1 ATOM 1397 N N . ASP A 1 178 ? 1.782 19.306 9.903 1.00 2.00 ? 178 ASP A N 1 ATOM 1398 C CA . ASP A 1 178 ? 1.293 18.406 8.848 1.00 2.61 ? 178 ASP A CA 1 ATOM 1399 C C . ASP A 1 178 ? 2.442 17.606 8.191 1.00 2.92 ? 178 ASP A C 1 ATOM 1400 O O . ASP A 1 178 ? 3.553 18.122 8.012 1.00 2.11 ? 178 ASP A O 1 ATOM 1401 C CB . ASP A 1 178 ? 0.499 19.225 7.809 1.00 2.75 ? 178 ASP A CB 1 ATOM 1402 C CG . ASP A 1 178 ? -0.919 19.573 8.247 1.00 4.23 ? 178 ASP A CG 1 ATOM 1403 O OD1 . ASP A 1 178 ? -1.627 18.681 8.766 1.00 2.27 ? 178 ASP A OD1 1 ATOM 1404 O OD2 . ASP A 1 178 ? -1.327 20.752 8.057 1.00 2.35 ? 178 ASP A OD2 1 ATOM 1405 N N . GLN A 1 179 ? 2.174 16.344 7.848 1.00 2.00 ? 179 GLN A N 1 ATOM 1406 C CA . GLN A 1 179 ? 3.186 15.487 7.236 1.00 2.00 ? 179 GLN A CA 1 ATOM 1407 C C . GLN A 1 179 ? 3.174 15.495 5.709 1.00 2.93 ? 179 GLN A C 1 ATOM 1408 O O . GLN A 1 179 ? 2.139 15.743 5.072 1.00 3.54 ? 179 GLN A O 1 ATOM 1409 C CB . GLN A 1 179 ? 3.035 14.047 7.747 1.00 2.09 ? 179 GLN A CB 1 ATOM 1410 C CG . GLN A 1 179 ? 3.418 13.899 9.224 1.00 2.62 ? 179 GLN A CG 1 ATOM 1411 C CD . GLN A 1 179 ? 2.315 14.349 10.157 1.00 3.15 ? 179 GLN A CD 1 ATOM 1412 O OE1 . GLN A 1 179 ? 1.306 14.876 9.712 1.00 4.28 ? 179 GLN A OE1 1 ATOM 1413 N NE2 . GLN A 1 179 ? 2.291 14.236 11.490 1.00 4.59 ? 179 GLN A NE2 1 ATOM 1414 N N . ILE A 1 180 ? 4.346 15.229 5.137 1.00 2.16 ? 180 ILE A N 1 ATOM 1415 C CA . ILE A 1 180 ? 4.542 15.288 3.703 1.00 2.14 ? 180 ILE A CA 1 ATOM 1416 C C . ILE A 1 180 ? 4.276 14.003 2.942 1.00 2.26 ? 180 ILE A C 1 ATOM 1417 O O . ILE A 1 180 ? 4.648 12.926 3.406 1.00 5.05 ? 180 ILE A O 1 ATOM 1418 C CB . ILE A 1 180 ? 5.984 15.686 3.408 1.00 2.31 ? 180 ILE A CB 1 ATOM 1419 C CG1 . ILE A 1 180 ? 6.353 16.896 4.258 1.00 2.00 ? 180 ILE A CG1 1 ATOM 1420 C CG2 . ILE A 1 180 ? 6.167 15.993 1.918 1.00 4.16 ? 180 ILE A CG2 1 ATOM 1421 C CD1 . ILE A 1 180 ? 7.750 17.422 4.019 1.00 2.00 ? 180 ILE A CD1 1 ATOM 1422 N N . ASN A 1 181 ? 3.642 14.128 1.796 1.00 2.02 ? 181 ASN A N 1 ATOM 1423 C CA . ASN A 1 181 ? 3.438 13.015 0.889 1.00 2.00 ? 181 ASN A CA 1 ATOM 1424 C C . ASN A 1 181 ? 4.499 13.192 -0.185 1.00 2.00 ? 181 ASN A C 1 ATOM 1425 O O . ASN A 1 181 ? 4.465 14.148 -0.963 1.00 2.00 ? 181 ASN A O 1 ATOM 1426 C CB . ASN A 1 181 ? 2.048 13.040 0.250 1.00 2.00 ? 181 ASN A CB 1 ATOM 1427 C CG . ASN A 1 181 ? 1.714 11.788 -0.553 1.00 2.00 ? 181 ASN A CG 1 ATOM 1428 O OD1 . ASN A 1 181 ? 2.476 10.828 -0.575 1.00 2.39 ? 181 ASN A OD1 1 ATOM 1429 N ND2 . ASN A 1 181 ? 0.561 11.796 -1.208 1.00 2.00 ? 181 ASN A ND2 1 ATOM 1430 N N . SER A 1 182 ? 5.443 12.265 -0.254 1.00 2.33 ? 182 SER A N 1 ATOM 1431 C CA . SER A 1 182 ? 6.502 12.332 -1.238 1.00 2.27 ? 182 SER A CA 1 ATOM 1432 C C . SER A 1 182 ? 6.206 11.624 -2.572 1.00 2.00 ? 182 SER A C 1 ATOM 1433 O O . SER A 1 182 ? 7.139 11.384 -3.346 1.00 2.00 ? 182 SER A O 1 ATOM 1434 C CB . SER A 1 182 ? 7.798 11.789 -0.627 1.00 3.69 ? 182 SER A CB 1 ATOM 1435 O OG . SER A 1 182 ? 7.657 10.425 -0.266 1.00 5.34 ? 182 SER A OG 1 ATOM 1436 N N . VAL A 1 183 ? 4.943 11.305 -2.832 1.00 2.00 ? 183 VAL A N 1 ATOM 1437 C CA . VAL A 1 183 ? 4.569 10.610 -4.052 1.00 2.00 ? 183 VAL A CA 1 ATOM 1438 C C . VAL A 1 183 ? 3.324 11.300 -4.655 1.00 3.70 ? 183 VAL A C 1 ATOM 1439 O O . VAL A 1 183 ? 2.535 11.900 -3.916 1.00 3.84 ? 183 VAL A O 1 ATOM 1440 C CB . VAL A 1 183 ? 4.271 9.126 -3.798 1.00 2.00 ? 183 VAL A CB 1 ATOM 1441 C CG1 . VAL A 1 183 ? 5.378 8.498 -2.955 1.00 2.00 ? 183 VAL A CG1 1 ATOM 1442 C CG2 . VAL A 1 183 ? 2.926 8.971 -3.118 1.00 2.14 ? 183 VAL A CG2 1 ATOM 1443 N N . THR A 1 184 ? 3.147 11.230 -5.968 1.00 3.02 ? 184 THR A N 1 ATOM 1444 C CA . THR A 1 184 ? 1.999 11.873 -6.584 1.00 2.50 ? 184 THR A CA 1 ATOM 1445 C C . THR A 1 184 ? 0.702 11.219 -6.146 1.00 2.05 ? 184 THR A C 1 ATOM 1446 O O . THR A 1 184 ? 0.600 10.001 -6.106 1.00 2.00 ? 184 THR A O 1 ATOM 1447 C CB . THR A 1 184 ? 2.092 11.833 -8.113 1.00 3.67 ? 184 THR A CB 1 ATOM 1448 O OG1 . THR A 1 184 ? 2.097 10.478 -8.561 1.00 2.98 ? 184 THR A OG1 1 ATOM 1449 C CG2 . THR A 1 184 ? 3.352 12.537 -8.579 1.00 4.10 ? 184 THR A CG2 1 ATOM 1450 N N . SER A 1 185 ? -0.286 12.051 -5.858 1.00 2.75 ? 185 SER A N 1 ATOM 1451 C CA . SER A 1 185 ? -1.594 11.594 -5.367 1.00 2.28 ? 185 SER A CA 1 ATOM 1452 C C . SER A 1 185 ? -2.512 10.917 -6.377 1.00 2.93 ? 185 SER A C 1 ATOM 1453 O O . SER A 1 185 ? -3.513 10.328 -5.985 1.00 3.28 ? 185 SER A O 1 ATOM 1454 C CB . SER A 1 185 ? -2.350 12.757 -4.745 1.00 2.31 ? 185 SER A CB 1 ATOM 1455 O OG . SER A 1 185 ? -1.732 13.167 -3.539 1.00 5.58 ? 185 SER A OG 1 ATOM 1456 N N . PHE A 1 186 ? -2.194 10.997 -7.663 1.00 2.04 ? 186 PHE A N 1 ATOM 1457 C CA . PHE A 1 186 ? -3.033 10.373 -8.684 1.00 2.00 ? 186 PHE A CA 1 ATOM 1458 C C . PHE A 1 186 ? -2.600 8.937 -8.942 1.00 2.00 ? 186 PHE A C 1 ATOM 1459 O O . PHE A 1 186 ? -1.441 8.613 -8.757 1.00 2.15 ? 186 PHE A O 1 ATOM 1460 C CB . PHE A 1 186 ? -2.915 11.157 -9.983 1.00 2.45 ? 186 PHE A CB 1 ATOM 1461 C CG . PHE A 1 186 ? -3.165 12.616 -9.826 1.00 2.00 ? 186 PHE A CG 1 ATOM 1462 C CD1 . PHE A 1 186 ? -4.461 13.115 -9.826 1.00 2.04 ? 186 PHE A CD1 1 ATOM 1463 C CD2 . PHE A 1 186 ? -2.108 13.492 -9.662 1.00 2.00 ? 186 PHE A CD2 1 ATOM 1464 C CE1 . PHE A 1 186 ? -4.699 14.471 -9.663 1.00 2.00 ? 186 PHE A CE1 1 ATOM 1465 C CE2 . PHE A 1 186 ? -2.333 14.845 -9.499 1.00 3.09 ? 186 PHE A CE2 1 ATOM 1466 C CZ . PHE A 1 186 ? -3.634 15.339 -9.499 1.00 2.34 ? 186 PHE A CZ 1 ATOM 1467 N N . LEU A 1 187 ? -3.518 8.077 -9.376 1.00 2.00 ? 187 LEU A N 1 ATOM 1468 C CA . LEU A 1 187 ? -3.158 6.687 -9.676 1.00 2.24 ? 187 LEU A CA 1 ATOM 1469 C C . LEU A 1 187 ? -2.475 6.658 -11.044 1.00 2.00 ? 187 LEU A C 1 ATOM 1470 O O . LEU A 1 187 ? -3.083 6.271 -12.041 1.00 2.00 ? 187 LEU A O 1 ATOM 1471 C CB . LEU A 1 187 ? -4.404 5.797 -9.710 1.00 2.40 ? 187 LEU A CB 1 ATOM 1472 C CG . LEU A 1 187 ? -4.363 4.546 -8.826 1.00 2.17 ? 187 LEU A CG 1 ATOM 1473 C CD1 . LEU A 1 187 ? -5.533 3.626 -9.157 1.00 2.84 ? 187 LEU A CD1 1 ATOM 1474 C CD2 . LEU A 1 187 ? -3.053 3.822 -9.048 1.00 3.55 ? 187 LEU A CD2 1 ATOM 1475 N N . ASP A 1 188 ? -1.202 7.044 -11.074 1.00 2.00 ? 188 ASP A N 1 ATOM 1476 C CA . ASP A 1 188 ? -0.450 7.125 -12.320 1.00 2.00 ? 188 ASP A CA 1 ATOM 1477 C C . ASP A 1 188 ? 0.794 6.244 -12.448 1.00 2.00 ? 188 ASP A C 1 ATOM 1478 O O . ASP A 1 188 ? 1.712 6.591 -13.189 1.00 2.06 ? 188 ASP A O 1 ATOM 1479 C CB . ASP A 1 188 ? -0.054 8.597 -12.529 1.00 2.00 ? 188 ASP A CB 1 ATOM 1480 C CG . ASP A 1 188 ? 0.648 9.190 -11.327 1.00 2.00 ? 188 ASP A CG 1 ATOM 1481 O OD1 . ASP A 1 188 ? 0.929 8.439 -10.371 1.00 2.00 ? 188 ASP A OD1 1 ATOM 1482 O OD2 . ASP A 1 188 ? 0.901 10.416 -11.334 1.00 2.22 ? 188 ASP A OD2 1 ATOM 1483 N N . ALA A 1 189 ? 0.836 5.125 -11.733 1.00 2.77 ? 189 ALA A N 1 ATOM 1484 C CA . ALA A 1 189 ? 1.979 4.209 -11.793 1.00 2.00 ? 189 ALA A CA 1 ATOM 1485 C C . ALA A 1 189 ? 3.299 4.925 -11.683 1.00 2.00 ? 189 ALA A C 1 ATOM 1486 O O . ALA A 1 189 ? 4.116 4.874 -12.584 1.00 2.00 ? 189 ALA A O 1 ATOM 1487 C CB . ALA A 1 189 ? 1.947 3.404 -13.078 1.00 2.00 ? 189 ALA A CB 1 ATOM 1488 N N . SER A 1 190 ? 3.500 5.554 -10.563 1.00 2.00 ? 190 SER A N 1 ATOM 1489 C CA . SER A 1 190 ? 4.736 6.288 -10.337 1.00 2.21 ? 190 SER A CA 1 ATOM 1490 C C . SER A 1 190 ? 5.596 5.602 -9.315 1.00 2.00 ? 190 SER A C 1 ATOM 1491 O O . SER A 1 190 ? 6.639 6.109 -8.906 1.00 2.00 ? 190 SER A O 1 ATOM 1492 C CB . SER A 1 190 ? 4.407 7.733 -9.920 1.00 2.89 ? 190 SER A CB 1 ATOM 1493 O OG . SER A 1 190 ? 3.689 7.757 -8.693 1.00 3.43 ? 190 SER A OG 1 ATOM 1494 N N . LEU A 1 191 ? 5.156 4.405 -8.934 1.00 2.70 ? 191 LEU A N 1 ATOM 1495 C CA . LEU A 1 191 ? 5.950 3.536 -8.111 1.00 2.35 ? 191 LEU A CA 1 ATOM 1496 C C . LEU A 1 191 ? 6.974 2.963 -9.089 1.00 3.05 ? 191 LEU A C 1 ATOM 1497 O O . LEU A 1 191 ? 8.013 2.436 -8.689 1.00 2.27 ? 191 LEU A O 1 ATOM 1498 C CB . LEU A 1 191 ? 5.119 2.404 -7.466 1.00 2.00 ? 191 LEU A CB 1 ATOM 1499 C CG . LEU A 1 191 ? 4.418 1.375 -8.396 1.00 2.00 ? 191 LEU A CG 1 ATOM 1500 C CD1 . LEU A 1 191 ? 3.884 0.199 -7.601 1.00 2.00 ? 191 LEU A CD1 1 ATOM 1501 C CD2 . LEU A 1 191 ? 3.285 2.048 -9.165 1.00 2.00 ? 191 LEU A CD2 1 ATOM 1502 N N . VAL A 1 192 ? 6.663 3.088 -10.379 1.00 3.37 ? 192 VAL A N 1 ATOM 1503 C CA . VAL A 1 192 ? 7.519 2.596 -11.447 1.00 2.38 ? 192 VAL A CA 1 ATOM 1504 C C . VAL A 1 192 ? 8.408 3.686 -12.016 1.00 3.89 ? 192 VAL A C 1 ATOM 1505 O O . VAL A 1 192 ? 9.629 3.573 -11.967 1.00 7.01 ? 192 VAL A O 1 ATOM 1506 C CB . VAL A 1 192 ? 6.700 2.028 -12.610 1.00 2.00 ? 192 VAL A CB 1 ATOM 1507 C CG1 . VAL A 1 192 ? 7.602 1.768 -13.797 1.00 2.00 ? 192 VAL A CG1 1 ATOM 1508 C CG2 . VAL A 1 192 ? 6.011 0.748 -12.183 1.00 2.00 ? 192 VAL A CG2 1 ATOM 1509 N N . TYR A 1 193 ? 7.798 4.742 -12.549 1.00 2.88 ? 193 TYR A N 1 ATOM 1510 C CA . TYR A 1 193 ? 8.546 5.836 -13.167 1.00 2.00 ? 193 TYR A CA 1 ATOM 1511 C C . TYR A 1 193 ? 9.174 6.852 -12.224 1.00 2.00 ? 193 TYR A C 1 ATOM 1512 O O . TYR A 1 193 ? 9.936 7.710 -12.662 1.00 2.00 ? 193 TYR A O 1 ATOM 1513 C CB . TYR A 1 193 ? 7.640 6.535 -14.174 1.00 2.00 ? 193 TYR A CB 1 ATOM 1514 C CG . TYR A 1 193 ? 7.103 5.546 -15.156 1.00 2.00 ? 193 TYR A CG 1 ATOM 1515 C CD1 . TYR A 1 193 ? 7.925 5.014 -16.144 1.00 2.07 ? 193 TYR A CD1 1 ATOM 1516 C CD2 . TYR A 1 193 ? 5.813 5.040 -15.026 1.00 2.08 ? 193 TYR A CD2 1 ATOM 1517 C CE1 . TYR A 1 193 ? 7.479 3.996 -16.976 1.00 2.70 ? 193 TYR A CE1 1 ATOM 1518 C CE2 . TYR A 1 193 ? 5.353 4.023 -15.849 1.00 2.00 ? 193 TYR A CE2 1 ATOM 1519 C CZ . TYR A 1 193 ? 6.192 3.507 -16.817 1.00 2.03 ? 193 TYR A CZ 1 ATOM 1520 O OH . TYR A 1 193 ? 5.746 2.496 -17.618 1.00 3.81 ? 193 TYR A OH 1 ATOM 1521 N N . GLY A 1 194 ? 8.858 6.749 -10.936 1.00 2.68 ? 194 GLY A N 1 ATOM 1522 C CA . GLY A 1 194 ? 9.401 7.668 -9.945 1.00 2.61 ? 194 GLY A CA 1 ATOM 1523 C C . GLY A 1 194 ? 8.644 8.980 -9.783 1.00 2.75 ? 194 GLY A C 1 ATOM 1524 O O . GLY A 1 194 ? 7.761 9.304 -10.582 1.00 2.46 ? 194 GLY A O 1 ATOM 1525 N N . SER A 1 195 ? 8.989 9.734 -8.738 1.00 3.98 ? 195 SER A N 1 ATOM 1526 C CA . SER A 1 195 ? 8.364 11.036 -8.454 1.00 4.18 ? 195 SER A CA 1 ATOM 1527 C C . SER A 1 195 ? 9.346 12.208 -8.503 1.00 4.98 ? 195 SER A C 1 ATOM 1528 O O . SER A 1 195 ? 9.069 13.274 -7.964 1.00 3.22 ? 195 SER A O 1 ATOM 1529 C CB . SER A 1 195 ? 7.708 11.037 -7.072 1.00 3.11 ? 195 SER A CB 1 ATOM 1530 O OG . SER A 1 195 ? 6.448 10.395 -7.082 1.00 5.87 ? 195 SER A OG 1 ATOM 1531 N N . GLU A 1 196 ? 10.494 12.022 -9.137 1.00 7.78 ? 196 GLU A N 1 ATOM 1532 C CA . GLU A 1 196 ? 11.468 13.105 -9.206 1.00 10.03 ? 196 GLU A CA 1 ATOM 1533 C C . GLU A 1 196 ? 12.062 13.233 -10.593 1.00 8.65 ? 196 GLU A C 1 ATOM 1534 O O . GLU A 1 196 ? 12.516 12.249 -11.175 1.00 8.04 ? 196 GLU A O 1 ATOM 1535 C CB . GLU A 1 196 ? 12.608 12.871 -8.218 1.00 15.53 ? 196 GLU A CB 1 ATOM 1536 C CG . GLU A 1 196 ? 12.191 12.662 -6.770 1.00 21.71 ? 196 GLU A CG 1 ATOM 1537 C CD . GLU A 1 196 ? 13.383 12.287 -5.897 1.00 24.30 ? 196 GLU A CD 1 ATOM 1538 O OE1 . GLU A 1 196 ? 14.426 12.975 -6.000 1.00 26.36 ? 196 GLU A OE1 1 ATOM 1539 O OE2 . GLU A 1 196 ? 13.281 11.311 -5.115 1.00 26.34 ? 196 GLU A OE2 1 ATOM 1540 N N . PRO A 1 197 ? 12.161 14.461 -11.064 1.00 7.40 ? 197 PRO A N 1 ATOM 1541 C CA . PRO A 1 197 ? 12.742 14.704 -12.396 1.00 6.72 ? 197 PRO A CA 1 ATOM 1542 C C . PRO A 1 197 ? 14.000 13.921 -12.625 1.00 5.63 ? 197 PRO A C 1 ATOM 1543 O O . PRO A 1 197 ? 14.132 13.168 -13.594 1.00 6.23 ? 197 PRO A O 1 ATOM 1544 C CB . PRO A 1 197 ? 12.756 16.212 -12.492 1.00 7.36 ? 197 PRO A CB 1 ATOM 1545 C CG . PRO A 1 197 ? 11.450 16.529 -11.845 1.00 6.66 ? 197 PRO A CG 1 ATOM 1546 C CD . PRO A 1 197 ? 11.104 15.450 -10.861 1.00 6.87 ? 197 PRO A CD 1 ATOM 1547 N N . SER A 1 198 ? 14.910 14.106 -11.693 1.00 4.47 ? 198 SER A N 1 ATOM 1548 C CA . SER A 1 198 ? 16.229 13.499 -11.651 1.00 5.31 ? 198 SER A CA 1 ATOM 1549 C C . SER A 1 198 ? 16.291 11.972 -11.509 1.00 5.71 ? 198 SER A C 1 ATOM 1550 O O . SER A 1 198 ? 17.134 11.335 -12.157 1.00 6.02 ? 198 SER A O 1 ATOM 1551 C CB . SER A 1 198 ? 16.999 14.115 -10.494 1.00 6.91 ? 198 SER A CB 1 ATOM 1552 O OG . SER A 1 198 ? 16.264 14.015 -9.281 1.00 11.41 ? 198 SER A OG 1 ATOM 1553 N N . LEU A 1 199 ? 15.468 11.388 -10.667 1.00 4.44 ? 199 LEU A N 1 ATOM 1554 C CA . LEU A 1 199 ? 15.459 9.951 -10.560 1.00 3.70 ? 199 LEU A CA 1 ATOM 1555 C C . LEU A 1 199 ? 14.736 9.422 -11.761 1.00 3.24 ? 199 LEU A C 1 ATOM 1556 O O . LEU A 1 199 ? 15.179 8.493 -12.423 1.00 3.66 ? 199 LEU A O 1 ATOM 1557 C CB . LEU A 1 199 ? 14.771 9.504 -9.274 1.00 3.19 ? 199 LEU A CB 1 ATOM 1558 C CG . LEU A 1 199 ? 14.263 8.086 -9.244 1.00 2.37 ? 199 LEU A CG 1 ATOM 1559 C CD1 . LEU A 1 199 ? 15.316 7.105 -9.742 1.00 3.00 ? 199 LEU A CD1 1 ATOM 1560 C CD2 . LEU A 1 199 ? 13.810 7.701 -7.839 1.00 2.39 ? 199 LEU A CD2 1 ATOM 1561 N N . ALA A 1 200 ? 13.597 10.038 -12.038 1.00 3.60 ? 200 ALA A N 1 ATOM 1562 C CA . ALA A 1 200 ? 12.754 9.641 -13.150 1.00 4.95 ? 200 ALA A CA 1 ATOM 1563 C C . ALA A 1 200 ? 13.583 9.302 -14.406 1.00 6.08 ? 200 ALA A C 1 ATOM 1564 O O . ALA A 1 200 ? 13.266 8.367 -15.143 1.00 6.95 ? 200 ALA A O 1 ATOM 1565 C CB . ALA A 1 200 ? 11.748 10.742 -13.476 1.00 5.24 ? 200 ALA A CB 1 ATOM 1566 N N . SER A 1 201 ? 14.650 10.106 -14.645 1.00 7.63 ? 201 SER A N 1 ATOM 1567 C CA . SER A 1 201 ? 15.534 9.945 -15.822 1.00 8.14 ? 201 SER A CA 1 ATOM 1568 C C . SER A 1 201 ? 16.498 8.745 -15.685 1.00 9.67 ? 201 SER A C 1 ATOM 1569 O O . SER A 1 201 ? 16.549 7.886 -16.556 1.00 10.28 ? 201 SER A O 1 ATOM 1570 C CB . SER A 1 201 ? 16.296 11.237 -16.097 1.00 7.83 ? 201 SER A CB 1 ATOM 1571 O OG . SER A 1 201 ? 17.457 11.316 -15.291 1.00 6.62 ? 201 SER A OG 1 ATOM 1572 N N . ARG A 1 202 ? 17.246 8.738 -14.580 1.00 10.69 ? 202 ARG A N 1 ATOM 1573 C CA . ARG A 1 202 ? 18.251 7.727 -14.215 1.00 11.56 ? 202 ARG A CA 1 ATOM 1574 C C . ARG A 1 202 ? 17.661 6.288 -14.261 1.00 9.03 ? 202 ARG A C 1 ATOM 1575 O O . ARG A 1 202 ? 18.369 5.301 -14.496 1.00 9.13 ? 202 ARG A O 1 ATOM 1576 C CB . ARG A 1 202 ? 18.851 8.105 -12.841 1.00 15.18 ? 202 ARG A CB 1 ATOM 1577 C CG . ARG A 1 202 ? 19.331 6.951 -11.980 1.00 22.31 ? 202 ARG A CG 1 ATOM 1578 C CD . ARG A 1 202 ? 20.467 7.400 -11.066 1.00 26.93 ? 202 ARG A CD 1 ATOM 1579 N NE . ARG A 1 202 ? 20.234 7.073 -9.659 1.00 31.34 ? 202 ARG A NE 1 ATOM 1580 C CZ . ARG A 1 202 ? 20.586 5.931 -9.069 1.00 33.37 ? 202 ARG A CZ 1 ATOM 1581 N NH1 . ARG A 1 202 ? 21.204 4.970 -9.752 1.00 34.70 ? 202 ARG A NH1 1 ATOM 1582 N NH2 . ARG A 1 202 ? 20.309 5.745 -7.784 1.00 34.57 ? 202 ARG A NH2 1 ATOM 1583 N N . LEU A 1 203 ? 16.363 6.207 -14.012 1.00 7.00 ? 203 LEU A N 1 ATOM 1584 C CA . LEU A 1 203 ? 15.648 4.945 -13.990 1.00 6.87 ? 203 LEU A CA 1 ATOM 1585 C C . LEU A 1 203 ? 15.414 4.350 -15.371 1.00 7.56 ? 203 LEU A C 1 ATOM 1586 O O . LEU A 1 203 ? 14.956 3.224 -15.499 1.00 7.25 ? 203 LEU A O 1 ATOM 1587 C CB . LEU A 1 203 ? 14.327 5.182 -13.263 1.00 5.57 ? 203 LEU A CB 1 ATOM 1588 C CG . LEU A 1 203 ? 13.824 4.183 -12.220 1.00 4.40 ? 203 LEU A CG 1 ATOM 1589 C CD1 . LEU A 1 203 ? 14.979 3.535 -11.489 1.00 4.14 ? 203 LEU A CD1 1 ATOM 1590 C CD2 . LEU A 1 203 ? 12.877 4.857 -11.251 1.00 3.13 ? 203 LEU A CD2 1 ATOM 1591 N N . ARG A 1 204 ? 15.730 5.147 -16.392 1.00 7.92 ? 204 ARG A N 1 ATOM 1592 C CA . ARG A 1 204 ? 15.571 4.774 -17.799 1.00 9.34 ? 204 ARG A CA 1 ATOM 1593 C C . ARG A 1 204 ? 16.896 4.499 -18.517 1.00 11.03 ? 204 ARG A C 1 ATOM 1594 O O . ARG A 1 204 ? 17.959 5.018 -18.136 1.00 9.15 ? 204 ARG A O 1 ATOM 1595 C CB . ARG A 1 204 ? 14.871 5.905 -18.558 1.00 9.54 ? 204 ARG A CB 1 ATOM 1596 C CG . ARG A 1 204 ? 13.737 6.576 -17.800 1.00 10.91 ? 204 ARG A CG 1 ATOM 1597 C CD . ARG A 1 204 ? 13.350 7.939 -18.409 1.00 11.59 ? 204 ARG A CD 1 ATOM 1598 N NE . ARG A 1 204 ? 13.383 7.952 -19.875 1.00 11.97 ? 204 ARG A NE 1 ATOM 1599 C CZ . ARG A 1 204 ? 12.905 8.935 -20.635 1.00 10.99 ? 204 ARG A CZ 1 ATOM 1600 N NH1 . ARG A 1 204 ? 12.340 10.002 -20.089 1.00 12.67 ? 204 ARG A NH1 1 ATOM 1601 N NH2 . ARG A 1 204 ? 13.010 8.857 -21.951 1.00 11.35 ? 204 ARG A NH2 1 ATOM 1602 N N . ASN A 1 205 ? 16.800 3.684 -19.573 1.00 12.68 ? 205 ASN A N 1 ATOM 1603 C CA . ASN A 1 205 ? 17.927 3.326 -20.441 1.00 13.73 ? 205 ASN A CA 1 ATOM 1604 C C . ASN A 1 205 ? 17.863 4.352 -21.578 1.00 13.18 ? 205 ASN A C 1 ATOM 1605 O O . ASN A 1 205 ? 17.164 4.145 -22.581 1.00 12.60 ? 205 ASN A O 1 ATOM 1606 C CB . ASN A 1 205 ? 17.752 1.895 -20.993 1.00 18.19 ? 205 ASN A CB 1 ATOM 1607 C CG . ASN A 1 205 ? 18.871 1.471 -21.949 1.00 22.34 ? 205 ASN A CG 1 ATOM 1608 O OD1 . ASN A 1 205 ? 19.690 2.287 -22.353 1.00 21.02 ? 205 ASN A OD1 1 ATOM 1609 N ND2 . ASN A 1 205 ? 18.868 0.192 -22.317 1.00 28.02 ? 205 ASN A ND2 1 ATOM 1610 N N . LEU A 1 206 ? 18.613 5.465 -21.407 1.00 10.97 ? 206 LEU A N 1 ATOM 1611 C CA . LEU A 1 206 ? 18.667 6.510 -22.400 1.00 7.65 ? 206 LEU A CA 1 ATOM 1612 C C . LEU A 1 206 ? 19.785 6.235 -23.462 1.00 8.11 ? 206 LEU A C 1 ATOM 1613 O O . LEU A 1 206 ? 19.940 7.007 -24.417 1.00 9.18 ? 206 LEU A O 1 ATOM 1614 C CB . LEU A 1 206 ? 18.801 7.869 -21.676 1.00 5.45 ? 206 LEU A CB 1 ATOM 1615 C CG . LEU A 1 206 ? 17.685 8.305 -20.682 1.00 3.11 ? 206 LEU A CG 1 ATOM 1616 C CD1 . LEU A 1 206 ? 18.003 9.674 -20.087 1.00 2.05 ? 206 LEU A CD1 1 ATOM 1617 C CD2 . LEU A 1 206 ? 16.326 8.306 -21.367 1.00 2.00 ? 206 LEU A CD2 1 ATOM 1618 N N . SER A 1 207 ? 20.568 5.133 -23.244 1.00 6.55 ? 207 SER A N 1 ATOM 1619 C CA . SER A 1 207 ? 21.682 4.689 -24.130 1.00 4.46 ? 207 SER A CA 1 ATOM 1620 C C . SER A 1 207 ? 21.121 4.045 -25.404 1.00 5.33 ? 207 SER A C 1 ATOM 1621 O O . SER A 1 207 ? 21.836 3.423 -26.178 1.00 5.09 ? 207 SER A O 1 ATOM 1622 C CB . SER A 1 207 ? 22.592 3.707 -23.375 1.00 4.90 ? 207 SER A CB 1 ATOM 1623 O OG . SER A 1 207 ? 22.277 3.690 -21.994 1.00 5.02 ? 207 SER A OG 1 ATOM 1624 N N . SER A 1 208 ? 19.789 4.221 -25.636 1.00 6.47 ? 208 SER A N 1 ATOM 1625 C CA . SER A 1 208 ? 19.040 3.657 -26.791 1.00 7.66 ? 208 SER A CA 1 ATOM 1626 C C . SER A 1 208 ? 17.756 4.475 -27.148 1.00 9.29 ? 208 SER A C 1 ATOM 1627 O O . SER A 1 208 ? 17.310 5.353 -26.407 1.00 12.40 ? 208 SER A O 1 ATOM 1628 C CB . SER A 1 208 ? 18.705 2.194 -26.531 1.00 7.34 ? 208 SER A CB 1 ATOM 1629 O OG . SER A 1 208 ? 17.310 1.969 -26.625 1.00 6.89 ? 208 SER A OG 1 ATOM 1630 N N . PRO A 1 209 ? 17.239 4.227 -28.355 1.00 8.97 ? 209 PRO A N 1 ATOM 1631 C CA . PRO A 1 209 ? 16.161 5.024 -29.027 1.00 8.15 ? 209 PRO A CA 1 ATOM 1632 C C . PRO A 1 209 ? 14.888 4.584 -28.567 1.00 7.44 ? 209 PRO A C 1 ATOM 1633 O O . PRO A 1 209 ? 13.829 5.219 -28.591 1.00 6.76 ? 209 PRO A O 1 ATOM 1634 C CB . PRO A 1 209 ? 16.212 4.643 -30.472 1.00 8.44 ? 209 PRO A CB 1 ATOM 1635 C CG . PRO A 1 209 ? 17.653 4.560 -30.704 1.00 8.76 ? 209 PRO A CG 1 ATOM 1636 C CD . PRO A 1 209 ? 18.298 4.338 -29.368 1.00 8.84 ? 209 PRO A CD 1 ATOM 1637 N N . LEU A 1 210 ? 15.097 3.376 -28.122 1.00 6.77 ? 210 LEU A N 1 ATOM 1638 C CA . LEU A 1 210 ? 13.930 2.521 -27.994 1.00 6.09 ? 210 LEU A CA 1 ATOM 1639 C C . LEU A 1 210 ? 12.988 2.935 -26.872 1.00 4.81 ? 210 LEU A C 1 ATOM 1640 O O . LEU A 1 210 ? 11.889 2.398 -26.748 1.00 4.45 ? 210 LEU A O 1 ATOM 1641 C CB . LEU A 1 210 ? 14.403 1.079 -27.826 1.00 7.93 ? 210 LEU A CB 1 ATOM 1642 C CG . LEU A 1 210 ? 15.238 0.683 -29.058 1.00 10.00 ? 210 LEU A CG 1 ATOM 1643 C CD1 . LEU A 1 210 ? 16.372 -0.272 -28.686 1.00 9.87 ? 210 LEU A CD1 1 ATOM 1644 C CD2 . LEU A 1 210 ? 14.307 0.080 -30.110 1.00 10.22 ? 210 LEU A CD2 1 ATOM 1645 N N . GLY A 1 211 ? 13.419 3.906 -26.070 1.00 5.03 ? 211 GLY A N 1 ATOM 1646 C CA . GLY A 1 211 ? 12.604 4.394 -24.967 1.00 4.08 ? 211 GLY A CA 1 ATOM 1647 C C . GLY A 1 211 ? 12.212 3.295 -24.001 1.00 3.07 ? 211 GLY A C 1 ATOM 1648 O O . GLY A 1 211 ? 11.065 2.861 -23.973 1.00 2.48 ? 211 GLY A O 1 ATOM 1649 N N . LEU A 1 212 ? 13.168 2.841 -23.202 1.00 2.69 ? 212 LEU A N 1 ATOM 1650 C CA . LEU A 1 212 ? 12.898 1.774 -22.260 1.00 2.50 ? 212 LEU A CA 1 ATOM 1651 C C . LEU A 1 212 ? 13.411 2.159 -20.884 1.00 3.75 ? 212 LEU A C 1 ATOM 1652 O O . LEU A 1 212 ? 14.177 3.125 -20.746 1.00 4.96 ? 212 LEU A O 1 ATOM 1653 C CB . LEU A 1 212 ? 13.607 0.487 -22.704 1.00 2.71 ? 212 LEU A CB 1 ATOM 1654 C CG . LEU A 1 212 ? 13.847 0.169 -24.189 1.00 2.00 ? 212 LEU A CG 1 ATOM 1655 C CD1 . LEU A 1 212 ? 14.564 -1.167 -24.306 1.00 2.00 ? 212 LEU A CD1 1 ATOM 1656 C CD2 . LEU A 1 212 ? 12.538 0.116 -24.949 1.00 2.00 ? 212 LEU A CD2 1 ATOM 1657 N N . MET A 1 213 ? 12.974 1.407 -19.871 1.00 4.08 ? 213 MET A N 1 ATOM 1658 C CA . MET A 1 213 ? 13.431 1.609 -18.497 1.00 2.52 ? 213 MET A CA 1 ATOM 1659 C C . MET A 1 213 ? 14.695 0.766 -18.445 1.00 2.49 ? 213 MET A C 1 ATOM 1660 O O . MET A 1 213 ? 14.768 -0.292 -19.076 1.00 2.70 ? 213 MET A O 1 ATOM 1661 C CB . MET A 1 213 ? 12.431 1.061 -17.474 1.00 2.42 ? 213 MET A CB 1 ATOM 1662 C CG . MET A 1 213 ? 11.094 1.772 -17.410 1.00 2.00 ? 213 MET A CG 1 ATOM 1663 S SD . MET A 1 213 ? 11.243 3.516 -16.991 1.00 2.00 ? 213 MET A SD 1 ATOM 1664 C CE . MET A 1 213 ? 11.311 3.435 -15.239 1.00 2.00 ? 213 MET A CE 1 ATOM 1665 N N . ALA A 1 214 ? 15.689 1.217 -17.699 1.00 2.00 ? 214 ALA A N 1 ATOM 1666 C CA . ALA A 1 214 ? 16.939 0.480 -17.626 1.00 2.00 ? 214 ALA A CA 1 ATOM 1667 C C . ALA A 1 214 ? 16.826 -0.802 -16.811 1.00 2.00 ? 214 ALA A C 1 ATOM 1668 O O . ALA A 1 214 ? 16.255 -0.792 -15.724 1.00 2.40 ? 214 ALA A O 1 ATOM 1669 C CB . ALA A 1 214 ? 18.014 1.376 -17.041 1.00 3.41 ? 214 ALA A CB 1 ATOM 1670 N N . VAL A 1 215 ? 17.372 -1.903 -17.333 1.00 2.63 ? 215 VAL A N 1 ATOM 1671 C CA . VAL A 1 215 ? 17.341 -3.180 -16.611 1.00 2.40 ? 215 VAL A CA 1 ATOM 1672 C C . VAL A 1 215 ? 18.697 -3.600 -16.031 1.00 2.30 ? 215 VAL A C 1 ATOM 1673 O O . VAL A 1 215 ? 19.739 -3.006 -16.313 1.00 2.00 ? 215 VAL A O 1 ATOM 1674 C CB . VAL A 1 215 ? 16.829 -4.341 -17.492 1.00 2.00 ? 215 VAL A CB 1 ATOM 1675 C CG1 . VAL A 1 215 ? 15.551 -3.942 -18.179 1.00 2.00 ? 215 VAL A CG1 1 ATOM 1676 C CG2 . VAL A 1 215 ? 17.883 -4.749 -18.483 1.00 2.39 ? 215 VAL A CG2 1 ATOM 1677 N N . ASN A 1 216 ? 18.663 -4.645 -15.216 1.00 3.53 ? 216 ASN A N 1 ATOM 1678 C CA . ASN A 1 216 ? 19.862 -5.163 -14.570 1.00 4.58 ? 216 ASN A CA 1 ATOM 1679 C C . ASN A 1 216 ? 20.773 -5.880 -15.559 1.00 4.12 ? 216 ASN A C 1 ATOM 1680 O O . ASN A 1 216 ? 20.329 -6.749 -16.310 1.00 2.17 ? 216 ASN A O 1 ATOM 1681 C CB . ASN A 1 216 ? 19.471 -6.113 -13.437 1.00 4.05 ? 216 ASN A CB 1 ATOM 1682 C CG . ASN A 1 216 ? 20.604 -6.359 -12.474 1.00 3.98 ? 216 ASN A CG 1 ATOM 1683 O OD1 . ASN A 1 216 ? 21.605 -6.980 -12.823 1.00 4.40 ? 216 ASN A OD1 1 ATOM 1684 N ND2 . ASN A 1 216 ? 20.458 -5.861 -11.251 1.00 5.19 ? 216 ASN A ND2 1 ATOM 1685 N N . GLN A 1 217 ? 22.052 -5.510 -15.542 1.00 6.08 ? 217 GLN A N 1 ATOM 1686 C CA . GLN A 1 217 ? 23.041 -6.099 -16.441 1.00 6.81 ? 217 GLN A CA 1 ATOM 1687 C C . GLN A 1 217 ? 23.816 -7.259 -15.831 1.00 8.82 ? 217 GLN A C 1 ATOM 1688 O O . GLN A 1 217 ? 24.560 -7.934 -16.538 1.00 8.37 ? 217 GLN A O 1 ATOM 1689 C CB . GLN A 1 217 ? 24.049 -5.041 -16.912 1.00 6.93 ? 217 GLN A CB 1 ATOM 1690 C CG . GLN A 1 217 ? 23.460 -3.915 -17.747 1.00 4.03 ? 217 GLN A CG 1 ATOM 1691 C CD . GLN A 1 217 ? 22.519 -4.427 -18.809 1.00 4.49 ? 217 GLN A CD 1 ATOM 1692 O OE1 . GLN A 1 217 ? 22.912 -5.200 -19.690 1.00 5.54 ? 217 GLN A OE1 1 ATOM 1693 N NE2 . GLN A 1 217 ? 21.260 -4.010 -18.729 1.00 3.36 ? 217 GLN A NE2 1 ATOM 1694 N N . GLU A 1 218 ? 23.658 -7.488 -14.528 1.00 10.91 ? 218 GLU A N 1 ATOM 1695 C CA . GLU A 1 218 ? 24.366 -8.584 -13.865 1.00 11.69 ? 218 GLU A CA 1 ATOM 1696 C C . GLU A 1 218 ? 23.584 -9.884 -13.716 1.00 11.18 ? 218 GLU A C 1 ATOM 1697 O O . GLU A 1 218 ? 24.180 -10.930 -13.475 1.00 12.45 ? 218 GLU A O 1 ATOM 1698 C CB . GLU A 1 218 ? 24.856 -8.164 -12.475 1.00 14.49 ? 218 GLU A CB 1 ATOM 1699 C CG . GLU A 1 218 ? 26.171 -7.416 -12.485 1.00 20.47 ? 218 GLU A CG 1 ATOM 1700 C CD . GLU A 1 218 ? 25.994 -5.925 -12.663 1.00 23.41 ? 218 GLU A CD 1 ATOM 1701 O OE1 . GLU A 1 218 ? 25.680 -5.249 -11.654 1.00 24.75 ? 218 GLU A OE1 1 ATOM 1702 O OE2 . GLU A 1 218 ? 26.163 -5.437 -13.808 1.00 25.37 ? 218 GLU A OE2 1 ATOM 1703 N N . ALA A 1 219 ? 22.264 -9.837 -13.854 1.00 10.61 ? 219 ALA A N 1 ATOM 1704 C CA . ALA A 1 219 ? 21.473 -11.048 -13.693 1.00 9.82 ? 219 ALA A CA 1 ATOM 1705 C C . ALA A 1 219 ? 20.162 -11.029 -14.451 1.00 10.62 ? 219 ALA A C 1 ATOM 1706 O O . ALA A 1 219 ? 19.464 -10.024 -14.471 1.00 11.06 ? 219 ALA A O 1 ATOM 1707 C CB . ALA A 1 219 ? 21.210 -11.284 -12.224 1.00 8.24 ? 219 ALA A CB 1 ATOM 1708 N N . TRP A 1 220 ? 19.831 -12.150 -15.072 1.00 12.85 ? 220 TRP A N 1 ATOM 1709 C CA . TRP A 1 220 ? 18.589 -12.256 -15.819 1.00 16.15 ? 220 TRP A CA 1 ATOM 1710 C C . TRP A 1 220 ? 17.748 -13.416 -15.307 1.00 15.76 ? 220 TRP A C 1 ATOM 1711 O O . TRP A 1 220 ? 18.230 -14.234 -14.523 1.00 16.13 ? 220 TRP A O 1 ATOM 1712 C CB . TRP A 1 220 ? 18.884 -12.429 -17.309 1.00 23.14 ? 220 TRP A CB 1 ATOM 1713 C CG . TRP A 1 220 ? 19.141 -11.125 -18.006 1.00 28.97 ? 220 TRP A CG 1 ATOM 1714 C CD1 . TRP A 1 220 ? 20.191 -10.269 -17.801 1.00 30.15 ? 220 TRP A CD1 1 ATOM 1715 C CD2 . TRP A 1 220 ? 18.272 -10.474 -18.942 1.00 30.61 ? 220 TRP A CD2 1 ATOM 1716 N NE1 . TRP A 1 220 ? 20.022 -9.125 -18.545 1.00 32.35 ? 220 TRP A NE1 1 ATOM 1717 C CE2 . TRP A 1 220 ? 18.850 -9.226 -19.256 1.00 32.40 ? 220 TRP A CE2 1 ATOM 1718 C CE3 . TRP A 1 220 ? 17.051 -10.826 -19.542 1.00 31.87 ? 220 TRP A CE3 1 ATOM 1719 C CZ2 . TRP A 1 220 ? 18.253 -8.320 -20.149 1.00 32.94 ? 220 TRP A CZ2 1 ATOM 1720 C CZ3 . TRP A 1 220 ? 16.455 -9.925 -20.427 1.00 33.03 ? 220 TRP A CZ3 1 ATOM 1721 C CH2 . TRP A 1 220 ? 17.059 -8.689 -20.722 1.00 32.46 ? 220 TRP A CH2 1 ATOM 1722 N N . ASP A 1 221 ? 16.490 -13.485 -15.734 1.00 13.70 ? 221 ASP A N 1 ATOM 1723 C CA . ASP A 1 221 ? 15.614 -14.562 -15.295 1.00 12.58 ? 221 ASP A CA 1 ATOM 1724 C C . ASP A 1 221 ? 15.028 -15.293 -16.493 1.00 12.41 ? 221 ASP A C 1 ATOM 1725 O O . ASP A 1 221 ? 14.009 -14.893 -17.055 1.00 10.73 ? 221 ASP A O 1 ATOM 1726 C CB . ASP A 1 221 ? 14.503 -14.012 -14.395 1.00 12.93 ? 221 ASP A CB 1 ATOM 1727 C CG . ASP A 1 221 ? 13.421 -15.038 -14.116 1.00 14.94 ? 221 ASP A CG 1 ATOM 1728 O OD1 . ASP A 1 221 ? 13.738 -16.250 -14.164 1.00 14.90 ? 221 ASP A OD1 1 ATOM 1729 O OD2 . ASP A 1 221 ? 12.264 -14.636 -13.839 1.00 15.01 ? 221 ASP A OD2 1 ATOM 1730 N N . HIS A 1 222 ? 15.697 -16.380 -16.866 1.00 13.33 ? 222 HIS A N 1 ATOM 1731 C CA . HIS A 1 222 ? 15.303 -17.201 -18.001 1.00 12.88 ? 222 HIS A CA 1 ATOM 1732 C C . HIS A 1 222 ? 15.078 -16.295 -19.199 1.00 10.90 ? 222 HIS A C 1 ATOM 1733 O O . HIS A 1 222 ? 14.008 -16.283 -19.804 1.00 9.85 ? 222 HIS A O 1 ATOM 1734 C CB . HIS A 1 222 ? 14.038 -18.010 -17.674 1.00 17.95 ? 222 HIS A CB 1 ATOM 1735 C CG . HIS A 1 222 ? 14.269 -19.116 -16.685 1.00 21.80 ? 222 HIS A CG 1 ATOM 1736 N ND1 . HIS A 1 222 ? 13.624 -19.181 -15.468 1.00 22.82 ? 222 HIS A ND1 1 ATOM 1737 C CD2 . HIS A 1 222 ? 15.095 -20.192 -16.725 1.00 23.12 ? 222 HIS A CD2 1 ATOM 1738 C CE1 . HIS A 1 222 ? 14.041 -20.242 -14.801 1.00 23.90 ? 222 HIS A CE1 1 ATOM 1739 N NE2 . HIS A 1 222 ? 14.937 -20.873 -15.544 1.00 24.03 ? 222 HIS A NE2 1 ATOM 1740 N N . GLY A 1 223 ? 16.114 -15.527 -19.522 1.00 10.03 ? 223 GLY A N 1 ATOM 1741 C CA . GLY A 1 223 ? 16.062 -14.607 -20.648 1.00 9.37 ? 223 GLY A CA 1 ATOM 1742 C C . GLY A 1 223 ? 15.063 -13.482 -20.459 1.00 8.19 ? 223 GLY A C 1 ATOM 1743 O O . GLY A 1 223 ? 14.473 -12.992 -21.428 1.00 9.14 ? 223 GLY A O 1 ATOM 1744 N N . LEU A 1 224 ? 14.881 -13.064 -19.208 1.00 6.85 ? 224 LEU A N 1 ATOM 1745 C CA . LEU A 1 224 ? 13.935 -12.008 -18.888 1.00 4.74 ? 224 LEU A CA 1 ATOM 1746 C C . LEU A 1 224 ? 14.509 -10.992 -17.937 1.00 3.18 ? 224 LEU A C 1 ATOM 1747 O O . LEU A 1 224 ? 15.439 -11.284 -17.190 1.00 3.06 ? 224 LEU A O 1 ATOM 1748 C CB . LEU A 1 224 ? 12.660 -12.612 -18.312 1.00 2.81 ? 224 LEU A CB 1 ATOM 1749 C CG . LEU A 1 224 ? 11.805 -13.182 -19.435 1.00 2.00 ? 224 LEU A CG 1 ATOM 1750 C CD1 . LEU A 1 224 ? 10.723 -14.077 -18.910 1.00 2.00 ? 224 LEU A CD1 1 ATOM 1751 C CD2 . LEU A 1 224 ? 11.223 -12.029 -20.199 1.00 2.00 ? 224 LEU A CD2 1 ATOM 1752 N N . ALA A 1 225 ? 13.924 -9.799 -17.981 1.00 3.96 ? 225 ALA A N 1 ATOM 1753 C CA . ALA A 1 225 ? 14.343 -8.650 -17.184 1.00 3.35 ? 225 ALA A CA 1 ATOM 1754 C C . ALA A 1 225 ? 14.147 -8.698 -15.679 1.00 2.00 ? 225 ALA A C 1 ATOM 1755 O O . ALA A 1 225 ? 13.291 -9.403 -15.157 1.00 2.00 ? 225 ALA A O 1 ATOM 1756 C CB . ALA A 1 225 ? 13.676 -7.390 -17.731 1.00 3.93 ? 225 ALA A CB 1 ATOM 1757 N N . TYR A 1 226 ? 14.961 -7.895 -15.008 1.00 2.00 ? 226 TYR A N 1 ATOM 1758 C CA . TYR A 1 226 ? 14.964 -7.729 -13.564 1.00 2.27 ? 226 TYR A CA 1 ATOM 1759 C C . TYR A 1 226 ? 15.226 -6.243 -13.376 1.00 2.00 ? 226 TYR A C 1 ATOM 1760 O O . TYR A 1 226 ? 15.777 -5.589 -14.256 1.00 2.00 ? 226 TYR A O 1 ATOM 1761 C CB . TYR A 1 226 ? 16.156 -8.446 -12.940 1.00 3.00 ? 226 TYR A CB 1 ATOM 1762 C CG . TYR A 1 226 ? 15.939 -9.818 -12.359 1.00 4.86 ? 226 TYR A CG 1 ATOM 1763 C CD1 . TYR A 1 226 ? 17.004 -10.501 -11.777 1.00 6.12 ? 226 TYR A CD1 1 ATOM 1764 C CD2 . TYR A 1 226 ? 14.696 -10.439 -12.381 1.00 6.22 ? 226 TYR A CD2 1 ATOM 1765 C CE1 . TYR A 1 226 ? 16.843 -11.763 -11.234 1.00 7.39 ? 226 TYR A CE1 1 ATOM 1766 C CE2 . TYR A 1 226 ? 14.522 -11.719 -11.832 1.00 6.82 ? 226 TYR A CE2 1 ATOM 1767 C CZ . TYR A 1 226 ? 15.606 -12.370 -11.263 1.00 7.66 ? 226 TYR A CZ 1 ATOM 1768 O OH . TYR A 1 226 ? 15.471 -13.633 -10.730 1.00 10.23 ? 226 TYR A OH 1 ATOM 1769 N N . PRO A 1 227 ? 14.806 -5.673 -12.250 1.00 2.00 ? 227 PRO A N 1 ATOM 1770 C CA . PRO A 1 227 ? 15.140 -4.254 -12.166 1.00 2.00 ? 227 PRO A CA 1 ATOM 1771 C C . PRO A 1 227 ? 16.636 -4.180 -11.800 1.00 2.55 ? 227 PRO A C 1 ATOM 1772 O O . PRO A 1 227 ? 17.235 -5.189 -11.412 1.00 2.00 ? 227 PRO A O 1 ATOM 1773 C CB . PRO A 1 227 ? 14.213 -3.742 -11.061 1.00 2.26 ? 227 PRO A CB 1 ATOM 1774 C CG . PRO A 1 227 ? 13.887 -4.968 -10.260 1.00 2.00 ? 227 PRO A CG 1 ATOM 1775 C CD . PRO A 1 227 ? 13.743 -6.031 -11.299 1.00 2.32 ? 227 PRO A CD 1 ATOM 1776 N N . PRO A 1 228 ? 17.261 -3.000 -11.942 1.00 2.00 ? 228 PRO A N 1 ATOM 1777 C CA . PRO A 1 228 ? 18.682 -2.819 -11.626 1.00 2.00 ? 228 PRO A CA 1 ATOM 1778 C C . PRO A 1 228 ? 18.890 -2.679 -10.135 1.00 2.59 ? 228 PRO A C 1 ATOM 1779 O O . PRO A 1 228 ? 18.029 -2.144 -9.442 1.00 4.52 ? 228 PRO A O 1 ATOM 1780 C CB . PRO A 1 228 ? 19.039 -1.523 -12.342 1.00 2.82 ? 228 PRO A CB 1 ATOM 1781 C CG . PRO A 1 228 ? 17.943 -1.357 -13.371 1.00 2.48 ? 228 PRO A CG 1 ATOM 1782 C CD . PRO A 1 228 ? 16.736 -1.808 -12.620 1.00 2.00 ? 228 PRO A CD 1 ATOM 1783 N N . PHE A 1 229 ? 20.037 -3.137 -9.645 1.00 3.69 ? 229 PHE A N 1 ATOM 1784 C CA . PHE A 1 229 ? 20.338 -3.051 -8.220 1.00 4.76 ? 229 PHE A CA 1 ATOM 1785 C C . PHE A 1 229 ? 20.543 -1.613 -7.810 1.00 6.38 ? 229 PHE A C 1 ATOM 1786 O O . PHE A 1 229 ? 20.796 -0.763 -8.646 1.00 7.43 ? 229 PHE A O 1 ATOM 1787 C CB . PHE A 1 229 ? 21.599 -3.837 -7.895 1.00 3.55 ? 229 PHE A CB 1 ATOM 1788 C CG . PHE A 1 229 ? 21.509 -5.286 -8.243 1.00 3.12 ? 229 PHE A CG 1 ATOM 1789 C CD1 . PHE A 1 229 ? 20.484 -6.067 -7.731 1.00 2.84 ? 229 PHE A CD1 1 ATOM 1790 C CD2 . PHE A 1 229 ? 22.452 -5.874 -9.076 1.00 2.89 ? 229 PHE A CD2 1 ATOM 1791 C CE1 . PHE A 1 229 ? 20.398 -7.407 -8.045 1.00 3.44 ? 229 PHE A CE1 1 ATOM 1792 C CE2 . PHE A 1 229 ? 22.373 -7.220 -9.396 1.00 2.85 ? 229 PHE A CE2 1 ATOM 1793 C CZ . PHE A 1 229 ? 21.344 -7.989 -8.881 1.00 2.95 ? 229 PHE A CZ 1 ATOM 1794 N N . ASN A 1 230 ? 20.445 -1.350 -6.517 1.00 9.71 ? 230 ASN A N 1 ATOM 1795 C CA . ASN A 1 230 ? 20.624 -0.010 -5.978 1.00 14.23 ? 230 ASN A CA 1 ATOM 1796 C C . ASN A 1 230 ? 22.054 0.171 -5.433 1.00 18.44 ? 230 ASN A C 1 ATOM 1797 O O . ASN A 1 230 ? 22.569 -0.690 -4.720 1.00 18.63 ? 230 ASN A O 1 ATOM 1798 C CB . ASN A 1 230 ? 19.583 0.208 -4.878 1.00 16.20 ? 230 ASN A CB 1 ATOM 1799 C CG . ASN A 1 230 ? 19.856 1.429 -4.037 1.00 17.43 ? 230 ASN A CG 1 ATOM 1800 O OD1 . ASN A 1 230 ? 19.802 2.560 -4.515 1.00 19.17 ? 230 ASN A OD1 1 ATOM 1801 N ND2 . ASN A 1 230 ? 20.143 1.206 -2.763 1.00 19.39 ? 230 ASN A ND2 1 ATOM 1802 N N . ASN A 1 231 ? 22.689 1.287 -5.786 1.00 23.03 ? 231 ASN A N 1 ATOM 1803 C CA . ASN A 1 231 ? 24.061 1.617 -5.361 1.00 26.19 ? 231 ASN A CA 1 ATOM 1804 C C . ASN A 1 231 ? 24.314 1.492 -3.865 1.00 27.18 ? 231 ASN A C 1 ATOM 1805 O O . ASN A 1 231 ? 25.156 0.705 -3.414 1.00 25.71 ? 231 ASN A O 1 ATOM 1806 C CB . ASN A 1 231 ? 24.400 3.056 -5.772 1.00 29.28 ? 231 ASN A CB 1 ATOM 1807 C CG . ASN A 1 231 ? 25.193 3.127 -7.058 1.00 32.70 ? 231 ASN A CG 1 ATOM 1808 O OD1 . ASN A 1 231 ? 25.291 2.141 -7.796 1.00 33.88 ? 231 ASN A OD1 1 ATOM 1809 N ND2 . ASN A 1 231 ? 25.763 4.301 -7.341 1.00 32.99 ? 231 ASN A ND2 1 ATOM 1810 N N . MET A 1 232 ? 23.587 2.334 -3.134 1.00 28.81 ? 232 MET A N 1 ATOM 1811 C CA . MET A 1 232 ? 23.600 2.461 -1.677 1.00 30.02 ? 232 MET A CA 1 ATOM 1812 C C . MET A 1 232 ? 24.379 1.466 -0.831 1.00 29.67 ? 232 MET A C 1 ATOM 1813 O O . MET A 1 232 ? 23.956 0.320 -0.659 1.00 29.44 ? 232 MET A O 1 ATOM 1814 C CB . MET A 1 232 ? 22.149 2.499 -1.178 1.00 33.37 ? 232 MET A CB 1 ATOM 1815 C CG . MET A 1 232 ? 21.950 2.450 0.348 1.00 37.38 ? 232 MET A CG 1 ATOM 1816 S SD . MET A 1 232 ? 20.171 2.356 0.808 1.00 42.06 ? 232 MET A SD 1 ATOM 1817 C CE . MET A 1 232 ? 20.248 1.897 2.574 1.00 39.18 ? 232 MET A CE 1 ATOM 1818 N N . LYS A 1 233 ? 25.519 1.897 -0.300 1.00 28.34 ? 233 LYS A N 1 ATOM 1819 C CA . LYS A 1 233 ? 26.238 1.013 0.588 1.00 27.66 ? 233 LYS A CA 1 ATOM 1820 C C . LYS A 1 233 ? 25.502 1.213 1.923 1.00 26.82 ? 233 LYS A C 1 ATOM 1821 O O . LYS A 1 233 ? 25.049 2.321 2.233 1.00 24.15 ? 233 LYS A O 1 ATOM 1822 C CB . LYS A 1 233 ? 27.737 1.306 0.574 1.00 29.34 ? 233 LYS A CB 1 ATOM 1823 C CG . LYS A 1 233 ? 28.441 0.368 -0.432 1.00 32.37 ? 233 LYS A CG 1 ATOM 1824 C CD . LYS A 1 233 ? 27.417 -0.603 -1.080 1.00 33.47 ? 233 LYS A CD 1 ATOM 1825 C CE . LYS A 1 233 ? 27.934 -1.252 -2.353 1.00 35.41 ? 233 LYS A CE 1 ATOM 1826 N NZ . LYS A 1 233 ? 29.070 -2.177 -2.096 1.00 36.32 ? 233 LYS A NZ 1 ATOM 1827 N N . PRO A 1 234 ? 25.443 0.159 2.752 1.00 26.20 ? 234 PRO A N 1 ATOM 1828 C CA . PRO A 1 234 ? 24.836 -0.152 4.033 1.00 24.19 ? 234 PRO A CA 1 ATOM 1829 C C . PRO A 1 234 ? 23.415 -0.397 3.582 1.00 22.94 ? 234 PRO A C 1 ATOM 1830 O O . PRO A 1 234 ? 22.449 0.216 4.032 1.00 25.09 ? 234 PRO A O 1 ATOM 1831 C CB . PRO A 1 234 ? 25.111 1.100 4.819 1.00 24.03 ? 234 PRO A CB 1 ATOM 1832 C CG . PRO A 1 234 ? 26.630 1.248 4.500 1.00 25.51 ? 234 PRO A CG 1 ATOM 1833 C CD . PRO A 1 234 ? 26.839 0.447 3.138 1.00 26.04 ? 234 PRO A CD 1 ATOM 1834 N N . SER A 1 235 ? 23.369 -1.303 2.610 1.00 19.65 ? 235 SER A N 1 ATOM 1835 C CA . SER A 1 235 ? 22.168 -1.784 1.962 1.00 17.06 ? 235 SER A CA 1 ATOM 1836 C C . SER A 1 235 ? 21.568 -2.840 2.897 1.00 15.22 ? 235 SER A C 1 ATOM 1837 O O . SER A 1 235 ? 22.302 -3.581 3.553 1.00 15.92 ? 235 SER A O 1 ATOM 1838 C CB . SER A 1 235 ? 22.571 -2.398 0.608 1.00 16.29 ? 235 SER A CB 1 ATOM 1839 O OG . SER A 1 235 ? 21.504 -3.070 -0.041 1.00 15.86 ? 235 SER A OG 1 ATOM 1840 N N . PRO A 1 236 ? 20.230 -2.902 2.996 1.00 12.04 ? 236 PRO A N 1 ATOM 1841 C CA . PRO A 1 236 ? 19.599 -3.893 3.872 1.00 11.63 ? 236 PRO A CA 1 ATOM 1842 C C . PRO A 1 236 ? 19.572 -5.257 3.208 1.00 11.74 ? 236 PRO A C 1 ATOM 1843 O O . PRO A 1 236 ? 19.720 -6.288 3.867 1.00 11.97 ? 236 PRO A O 1 ATOM 1844 C CB . PRO A 1 236 ? 18.184 -3.349 4.066 1.00 10.69 ? 236 PRO A CB 1 ATOM 1845 C CG . PRO A 1 236 ? 18.308 -1.899 3.747 1.00 11.68 ? 236 PRO A CG 1 ATOM 1846 C CD . PRO A 1 236 ? 19.246 -1.897 2.577 1.00 12.00 ? 236 PRO A CD 1 ATOM 1847 N N . CYS A 1 237 ? 19.381 -5.240 1.891 1.00 12.04 ? 237 CYS A N 1 ATOM 1848 C CA . CYS A 1 237 ? 19.304 -6.459 1.088 1.00 10.41 ? 237 CYS A CA 1 ATOM 1849 C C . CYS A 1 237 ? 20.525 -7.351 1.238 1.00 8.65 ? 237 CYS A C 1 ATOM 1850 O O . CYS A 1 237 ? 20.388 -8.565 1.311 1.00 7.96 ? 237 CYS A O 1 ATOM 1851 C CB . CYS A 1 237 ? 19.054 -6.105 -0.392 1.00 8.93 ? 237 CYS A CB 1 ATOM 1852 S SG . CYS A 1 237 ? 17.383 -5.405 -0.674 1.00 7.92 ? 237 CYS A SG 1 ATOM 1853 N N . GLU A 1 238 ? 21.707 -6.743 1.305 1.00 8.21 ? 238 GLU A N 1 ATOM 1854 C CA . GLU A 1 238 ? 22.959 -7.480 1.461 1.00 8.81 ? 238 GLU A CA 1 ATOM 1855 C C . GLU A 1 238 ? 23.119 -8.009 2.891 1.00 9.85 ? 238 GLU A C 1 ATOM 1856 O O . GLU A 1 238 ? 23.572 -9.142 3.099 1.00 8.68 ? 238 GLU A O 1 ATOM 1857 C CB . GLU A 1 238 ? 24.164 -6.582 1.128 1.00 10.10 ? 238 GLU A CB 1 ATOM 1858 C CG . GLU A 1 238 ? 24.307 -6.168 -0.347 1.00 13.51 ? 238 GLU A CG 1 ATOM 1859 C CD . GLU A 1 238 ? 25.543 -5.286 -0.614 1.00 14.70 ? 238 GLU A CD 1 ATOM 1860 O OE1 . GLU A 1 238 ? 25.647 -4.720 -1.727 1.00 15.31 ? 238 GLU A OE1 1 ATOM 1861 O OE2 . GLU A 1 238 ? 26.411 -5.159 0.282 1.00 14.86 ? 238 GLU A OE2 1 ATOM 1862 N N . PHE A 1 239 ? 22.748 -7.186 3.873 1.00 9.61 ? 239 PHE A N 1 ATOM 1863 C CA . PHE A 1 239 ? 22.866 -7.561 5.283 1.00 8.92 ? 239 PHE A CA 1 ATOM 1864 C C . PHE A 1 239 ? 22.168 -8.875 5.583 1.00 9.05 ? 239 PHE A C 1 ATOM 1865 O O . PHE A 1 239 ? 22.699 -9.713 6.313 1.00 7.45 ? 239 PHE A O 1 ATOM 1866 C CB . PHE A 1 239 ? 22.292 -6.466 6.185 1.00 10.84 ? 239 PHE A CB 1 ATOM 1867 C CG . PHE A 1 239 ? 22.518 -6.707 7.663 1.00 13.06 ? 239 PHE A CG 1 ATOM 1868 C CD1 . PHE A 1 239 ? 23.802 -6.908 8.162 1.00 14.37 ? 239 PHE A CD1 1 ATOM 1869 C CD2 . PHE A 1 239 ? 21.447 -6.698 8.561 1.00 13.57 ? 239 PHE A CD2 1 ATOM 1870 C CE1 . PHE A 1 239 ? 24.016 -7.092 9.530 1.00 15.39 ? 239 PHE A CE1 1 ATOM 1871 C CE2 . PHE A 1 239 ? 21.648 -6.881 9.930 1.00 12.86 ? 239 PHE A CE2 1 ATOM 1872 C CZ . PHE A 1 239 ? 22.931 -7.077 10.416 1.00 15.23 ? 239 PHE A CZ 1 ATOM 1873 N N . ILE A 1 240 ? 20.974 -9.051 5.025 1.00 9.91 ? 240 ILE A N 1 ATOM 1874 C CA . ILE A 1 240 ? 20.226 -10.279 5.245 1.00 11.16 ? 240 ILE A CA 1 ATOM 1875 C C . ILE A 1 240 ? 21.188 -11.430 5.114 1.00 12.14 ? 240 ILE A C 1 ATOM 1876 O O . ILE A 1 240 ? 21.475 -12.127 6.087 1.00 14.07 ? 240 ILE A O 1 ATOM 1877 C CB . ILE A 1 240 ? 19.078 -10.451 4.225 1.00 9.88 ? 240 ILE A CB 1 ATOM 1878 C CG1 . ILE A 1 240 ? 17.895 -9.587 4.653 1.00 9.89 ? 240 ILE A CG1 1 ATOM 1879 C CG2 . ILE A 1 240 ? 18.648 -11.923 4.139 1.00 10.17 ? 240 ILE A CG2 1 ATOM 1880 C CD1 . ILE A 1 240 ? 17.501 -9.794 6.111 1.00 9.83 ? 240 ILE A CD1 1 ATOM 1881 N N . ASN A 1 241 ? 21.695 -11.623 3.906 1.00 13.58 ? 241 ASN A N 1 ATOM 1882 C CA . ASN A 1 241 ? 22.645 -12.686 3.673 1.00 15.11 ? 241 ASN A CA 1 ATOM 1883 C C . ASN A 1 241 ? 23.906 -12.157 3.018 1.00 16.03 ? 241 ASN A C 1 ATOM 1884 O O . ASN A 1 241 ? 23.931 -11.856 1.819 1.00 15.55 ? 241 ASN A O 1 ATOM 1885 C CB . ASN A 1 241 ? 22.046 -13.775 2.803 1.00 16.03 ? 241 ASN A CB 1 ATOM 1886 C CG . ASN A 1 241 ? 23.000 -14.914 2.599 1.00 18.79 ? 241 ASN A CG 1 ATOM 1887 O OD1 . ASN A 1 241 ? 24.066 -14.750 2.014 1.00 16.92 ? 241 ASN A OD1 1 ATOM 1888 N ND2 . ASN A 1 241 ? 22.623 -16.075 3.108 1.00 24.76 ? 241 ASN A ND2 1 ATOM 1889 N N . THR A 1 242 ? 24.952 -12.043 3.831 1.00 17.15 ? 242 THR A N 1 ATOM 1890 C CA . THR A 1 242 ? 26.249 -11.563 3.381 1.00 17.28 ? 242 THR A CA 1 ATOM 1891 C C . THR A 1 242 ? 26.904 -12.533 2.389 1.00 17.46 ? 242 THR A C 1 ATOM 1892 O O . THR A 1 242 ? 27.580 -12.106 1.454 1.00 18.94 ? 242 THR A O 1 ATOM 1893 C CB . THR A 1 242 ? 27.186 -11.344 4.586 1.00 16.30 ? 242 THR A CB 1 ATOM 1894 O OG1 . THR A 1 242 ? 27.189 -12.519 5.410 1.00 14.28 ? 242 THR A OG1 1 ATOM 1895 C CG2 . THR A 1 242 ? 26.716 -10.151 5.407 1.00 15.58 ? 242 THR A CG2 1 ATOM 1896 N N . THR A 1 243 ? 26.703 -13.833 2.582 1.00 17.01 ? 243 THR A N 1 ATOM 1897 C CA . THR A 1 243 ? 27.290 -14.817 1.674 1.00 16.50 ? 243 THR A CA 1 ATOM 1898 C C . THR A 1 243 ? 26.817 -14.560 0.244 1.00 14.88 ? 243 THR A C 1 ATOM 1899 O O . THR A 1 243 ? 27.623 -14.464 -0.684 1.00 13.52 ? 243 THR A O 1 ATOM 1900 C CB . THR A 1 243 ? 26.899 -16.264 2.055 1.00 17.46 ? 243 THR A CB 1 ATOM 1901 O OG1 . THR A 1 243 ? 27.373 -16.567 3.374 1.00 18.09 ? 243 THR A OG1 1 ATOM 1902 C CG2 . THR A 1 243 ? 27.502 -17.252 1.063 1.00 17.40 ? 243 THR A CG2 1 ATOM 1903 N N . ALA A 1 244 ? 25.502 -14.458 0.076 1.00 13.92 ? 244 ALA A N 1 ATOM 1904 C CA . ALA A 1 244 ? 24.916 -14.210 -1.235 1.00 12.88 ? 244 ALA A CA 1 ATOM 1905 C C . ALA A 1 244 ? 25.344 -12.833 -1.694 1.00 12.12 ? 244 ALA A C 1 ATOM 1906 O O . ALA A 1 244 ? 25.846 -12.669 -2.799 1.00 12.22 ? 244 ALA A O 1 ATOM 1907 C CB . ALA A 1 244 ? 23.397 -14.292 -1.164 1.00 12.28 ? 244 ALA A CB 1 ATOM 1908 N N . ARG A 1 245 ? 25.131 -11.841 -0.842 1.00 12.68 ? 245 ARG A N 1 ATOM 1909 C CA . ARG A 1 245 ? 25.527 -10.478 -1.169 1.00 13.73 ? 245 ARG A CA 1 ATOM 1910 C C . ARG A 1 245 ? 24.790 -9.976 -2.411 1.00 10.45 ? 245 ARG A C 1 ATOM 1911 O O . ARG A 1 245 ? 25.396 -9.703 -3.448 1.00 7.43 ? 245 ARG A O 1 ATOM 1912 C CB . ARG A 1 245 ? 27.043 -10.446 -1.385 1.00 19.20 ? 245 ARG A CB 1 ATOM 1913 C CG . ARG A 1 245 ? 27.727 -9.145 -1.010 1.00 27.21 ? 245 ARG A CG 1 ATOM 1914 C CD . ARG A 1 245 ? 29.144 -9.424 -0.497 1.00 33.28 ? 245 ARG A CD 1 ATOM 1915 N NE . ARG A 1 245 ? 29.215 -9.426 0.967 1.00 39.85 ? 245 ARG A NE 1 ATOM 1916 C CZ . ARG A 1 245 ? 29.727 -10.415 1.698 1.00 42.53 ? 245 ARG A CZ 1 ATOM 1917 N NH1 . ARG A 1 245 ? 30.217 -11.502 1.110 1.00 43.74 ? 245 ARG A NH1 1 ATOM 1918 N NH2 . ARG A 1 245 ? 29.753 -10.314 3.025 1.00 45.66 ? 245 ARG A NH2 1 ATOM 1919 N N . VAL A 1 246 ? 23.471 -9.873 -2.293 1.00 8.12 ? 246 VAL A N 1 ATOM 1920 C CA . VAL A 1 246 ? 22.640 -9.402 -3.392 1.00 5.88 ? 246 VAL A CA 1 ATOM 1921 C C . VAL A 1 246 ? 21.933 -8.118 -2.968 1.00 5.37 ? 246 VAL A C 1 ATOM 1922 O O . VAL A 1 246 ? 21.105 -8.115 -2.054 1.00 6.14 ? 246 VAL A O 1 ATOM 1923 C CB . VAL A 1 246 ? 21.589 -10.458 -3.803 1.00 5.23 ? 246 VAL A CB 1 ATOM 1924 C CG1 . VAL A 1 246 ? 20.766 -9.941 -4.980 1.00 5.00 ? 246 VAL A CG1 1 ATOM 1925 C CG2 . VAL A 1 246 ? 22.282 -11.763 -4.170 1.00 3.36 ? 246 VAL A CG2 1 ATOM 1926 N N . PRO A 1 247 ? 22.250 -7.006 -3.638 1.00 4.64 ? 247 PRO A N 1 ATOM 1927 C CA . PRO A 1 247 ? 21.667 -5.696 -3.345 1.00 5.33 ? 247 PRO A CA 1 ATOM 1928 C C . PRO A 1 247 ? 20.171 -5.528 -3.630 1.00 5.38 ? 247 PRO A C 1 ATOM 1929 O O . PRO A 1 247 ? 19.536 -6.355 -4.301 1.00 4.89 ? 247 PRO A O 1 ATOM 1930 C CB . PRO A 1 247 ? 22.527 -4.751 -4.180 1.00 5.33 ? 247 PRO A CB 1 ATOM 1931 C CG . PRO A 1 247 ? 22.839 -5.595 -5.382 1.00 4.92 ? 247 PRO A CG 1 ATOM 1932 C CD . PRO A 1 247 ? 23.182 -6.927 -4.774 1.00 3.97 ? 247 PRO A CD 1 ATOM 1933 N N . CYS A 1 248 ? 19.628 -4.438 -3.093 1.00 4.70 ? 248 CYS A N 1 ATOM 1934 C CA . CYS A 1 248 ? 18.230 -4.086 -3.263 1.00 3.30 ? 248 CYS A CA 1 ATOM 1935 C C . CYS A 1 248 ? 17.953 -3.667 -4.702 1.00 3.47 ? 248 CYS A C 1 ATOM 1936 O O . CYS A 1 248 ? 18.835 -3.179 -5.411 1.00 2.38 ? 248 CYS A O 1 ATOM 1937 C CB . CYS A 1 248 ? 17.871 -2.932 -2.332 1.00 4.72 ? 248 CYS A CB 1 ATOM 1938 S SG . CYS A 1 248 ? 17.649 -3.399 -0.593 1.00 4.31 ? 248 CYS A SG 1 ATOM 1939 N N . PHE A 1 249 ? 16.720 -3.857 -5.139 1.00 2.53 ? 249 PHE A N 1 ATOM 1940 C CA . PHE A 1 249 ? 16.380 -3.471 -6.485 1.00 2.00 ? 249 PHE A CA 1 ATOM 1941 C C . PHE A 1 249 ? 16.111 -1.996 -6.524 1.00 2.32 ? 249 PHE A C 1 ATOM 1942 O O . PHE A 1 249 ? 15.642 -1.417 -5.552 1.00 4.73 ? 249 PHE A O 1 ATOM 1943 C CB . PHE A 1 249 ? 15.152 -4.222 -6.964 1.00 2.00 ? 249 PHE A CB 1 ATOM 1944 C CG . PHE A 1 249 ? 15.461 -5.562 -7.524 1.00 2.00 ? 249 PHE A CG 1 ATOM 1945 C CD1 . PHE A 1 249 ? 16.696 -5.804 -8.111 1.00 2.00 ? 249 PHE A CD1 1 ATOM 1946 C CD2 . PHE A 1 249 ? 14.508 -6.569 -7.518 1.00 2.01 ? 249 PHE A CD2 1 ATOM 1947 C CE1 . PHE A 1 249 ? 16.975 -7.025 -8.685 1.00 2.65 ? 249 PHE A CE1 1 ATOM 1948 C CE2 . PHE A 1 249 ? 14.776 -7.794 -8.090 1.00 2.00 ? 249 PHE A CE2 1 ATOM 1949 C CZ . PHE A 1 249 ? 16.014 -8.025 -8.676 1.00 2.81 ? 249 PHE A CZ 1 ATOM 1950 N N . GLN A 1 250 ? 16.419 -1.381 -7.650 1.00 2.00 ? 250 GLN A N 1 ATOM 1951 C CA . GLN A 1 250 ? 16.173 0.032 -7.797 1.00 2.52 ? 250 GLN A CA 1 ATOM 1952 C C . GLN A 1 250 ? 14.892 0.205 -8.582 1.00 3.41 ? 250 GLN A C 1 ATOM 1953 O O . GLN A 1 250 ? 14.806 -0.234 -9.723 1.00 4.91 ? 250 GLN A O 1 ATOM 1954 C CB . GLN A 1 250 ? 17.315 0.683 -8.544 1.00 2.00 ? 250 GLN A CB 1 ATOM 1955 C CG . GLN A 1 250 ? 17.007 2.086 -8.932 1.00 4.18 ? 250 GLN A CG 1 ATOM 1956 C CD . GLN A 1 250 ? 18.204 2.972 -8.789 1.00 6.09 ? 250 GLN A CD 1 ATOM 1957 O OE1 . GLN A 1 250 ? 19.153 2.893 -9.577 1.00 7.44 ? 250 GLN A OE1 1 ATOM 1958 N NE2 . GLN A 1 250 ? 18.184 3.821 -7.762 1.00 6.73 ? 250 GLN A NE2 1 ATOM 1959 N N . ALA A 1 251 ? 13.892 0.841 -7.989 1.00 2.55 ? 251 ALA A N 1 ATOM 1960 C CA . ALA A 1 251 ? 12.637 1.031 -8.698 1.00 2.00 ? 251 ALA A CA 1 ATOM 1961 C C . ALA A 1 251 ? 12.111 2.448 -8.539 1.00 2.40 ? 251 ALA A C 1 ATOM 1962 O O . ALA A 1 251 ? 12.704 3.261 -7.833 1.00 2.03 ? 251 ALA A O 1 ATOM 1963 C CB . ALA A 1 251 ? 11.613 0.029 -8.198 1.00 2.48 ? 251 ALA A CB 1 ATOM 1964 N N . GLY A 1 252 ? 10.989 2.735 -9.193 1.00 2.77 ? 252 GLY A N 1 ATOM 1965 C CA . GLY A 1 252 ? 10.395 4.060 -9.113 1.00 2.44 ? 252 GLY A CA 1 ATOM 1966 C C . GLY A 1 252 ? 9.969 4.514 -7.723 1.00 3.70 ? 252 GLY A C 1 ATOM 1967 O O . GLY A 1 252 ? 9.628 5.686 -7.541 1.00 5.59 ? 252 GLY A O 1 ATOM 1968 N N . ASP A 1 253 ? 9.982 3.599 -6.751 1.00 3.25 ? 253 ASP A N 1 ATOM 1969 C CA . ASP A 1 253 ? 9.599 3.898 -5.364 1.00 3.29 ? 253 ASP A CA 1 ATOM 1970 C C . ASP A 1 253 ? 10.483 3.161 -4.358 1.00 3.36 ? 253 ASP A C 1 ATOM 1971 O O . ASP A 1 253 ? 10.699 1.961 -4.479 1.00 3.63 ? 253 ASP A O 1 ATOM 1972 C CB . ASP A 1 253 ? 8.144 3.491 -5.111 1.00 5.53 ? 253 ASP A CB 1 ATOM 1973 C CG . ASP A 1 253 ? 7.747 3.597 -3.629 1.00 7.89 ? 253 ASP A CG 1 ATOM 1974 O OD1 . ASP A 1 253 ? 7.621 4.743 -3.123 1.00 6.58 ? 253 ASP A OD1 1 ATOM 1975 O OD2 . ASP A 1 253 ? 7.568 2.535 -2.976 1.00 7.39 ? 253 ASP A OD2 1 ATOM 1976 N N . SER A 1 254 ? 10.968 3.871 -3.347 1.00 3.79 ? 254 SER A N 1 ATOM 1977 C CA . SER A 1 254 ? 11.848 3.262 -2.330 1.00 4.08 ? 254 SER A CA 1 ATOM 1978 C C . SER A 1 254 ? 11.432 1.855 -1.881 1.00 4.71 ? 254 SER A C 1 ATOM 1979 O O . SER A 1 254 ? 12.147 0.898 -2.161 1.00 8.34 ? 254 SER A O 1 ATOM 1980 C CB . SER A 1 254 ? 11.887 4.141 -1.078 1.00 4.17 ? 254 SER A CB 1 ATOM 1981 O OG . SER A 1 254 ? 12.479 5.392 -1.359 1.00 8.38 ? 254 SER A OG 1 ATOM 1982 N N . ARG A 1 255 ? 10.271 1.715 -1.231 1.00 3.52 ? 255 ARG A N 1 ATOM 1983 C CA . ARG A 1 255 ? 9.873 0.409 -0.665 1.00 2.54 ? 255 ARG A CA 1 ATOM 1984 C C . ARG A 1 255 ? 9.880 -0.831 -1.594 1.00 2.45 ? 255 ARG A C 1 ATOM 1985 O O . ARG A 1 255 ? 9.777 -1.974 -1.119 1.00 2.00 ? 255 ARG A O 1 ATOM 1986 C CB . ARG A 1 255 ? 8.541 0.539 0.068 1.00 2.50 ? 255 ARG A CB 1 ATOM 1987 C CG . ARG A 1 255 ? 8.335 1.805 0.867 1.00 2.00 ? 255 ARG A CG 1 ATOM 1988 C CD . ARG A 1 255 ? 7.500 2.751 0.018 1.00 3.19 ? 255 ARG A CD 1 ATOM 1989 N NE . ARG A 1 255 ? 6.596 3.557 0.837 1.00 2.46 ? 255 ARG A NE 1 ATOM 1990 C CZ . ARG A 1 255 ? 5.555 4.179 0.324 1.00 2.00 ? 255 ARG A CZ 1 ATOM 1991 N NH1 . ARG A 1 255 ? 5.283 4.060 -0.974 1.00 2.00 ? 255 ARG A NH1 1 ATOM 1992 N NH2 . ARG A 1 255 ? 4.785 4.924 1.104 1.00 2.00 ? 255 ARG A NH2 1 ATOM 1993 N N . ALA A 1 256 ? 10.010 -0.608 -2.864 1.00 2.08 ? 256 ALA A N 1 ATOM 1994 C CA . ALA A 1 256 ? 10.032 -1.690 -3.849 1.00 2.00 ? 256 ALA A CA 1 ATOM 1995 C C . ALA A 1 256 ? 10.534 -3.053 -3.375 1.00 2.00 ? 256 ALA A C 1 ATOM 1996 O O . ALA A 1 256 ? 10.061 -4.077 -3.850 1.00 2.00 ? 256 ALA A O 1 ATOM 1997 C CB . ALA A 1 256 ? 10.854 -1.231 -5.044 1.00 2.00 ? 256 ALA A CB 1 ATOM 1998 N N . SER A 1 257 ? 11.477 -3.100 -2.446 1.00 2.47 ? 257 SER A N 1 ATOM 1999 C CA . SER A 1 257 ? 11.972 -4.415 -2.022 1.00 3.90 ? 257 SER A CA 1 ATOM 2000 C C . SER A 1 257 ? 11.788 -4.772 -0.503 1.00 2.02 ? 257 SER A C 1 ATOM 2001 O O . SER A 1 257 ? 12.640 -5.430 0.089 1.00 2.00 ? 257 SER A O 1 ATOM 2002 C CB . SER A 1 257 ? 13.435 -4.578 -2.430 1.00 4.05 ? 257 SER A CB 1 ATOM 2003 O OG . SER A 1 257 ? 14.082 -3.319 -2.510 1.00 7.04 ? 257 SER A OG 1 ATOM 2004 N N . GLU A 1 258 ? 10.678 -4.345 0.131 1.00 2.74 ? 258 GLU A N 1 ATOM 2005 C CA . GLU A 1 258 ? 10.463 -4.696 1.579 1.00 2.00 ? 258 GLU A CA 1 ATOM 2006 C C . GLU A 1 258 ? 10.128 -6.185 1.656 1.00 2.00 ? 258 GLU A C 1 ATOM 2007 O O . GLU A 1 258 ? 10.309 -6.788 2.712 1.00 2.15 ? 258 GLU A O 1 ATOM 2008 C CB . GLU A 1 258 ? 9.306 -3.910 2.270 1.00 2.00 ? 258 GLU A CB 1 ATOM 2009 C CG . GLU A 1 258 ? 8.996 -4.358 3.721 1.00 2.40 ? 258 GLU A CG 1 ATOM 2010 C CD . GLU A 1 258 ? 7.517 -4.761 3.986 1.00 2.00 ? 258 GLU A CD 1 ATOM 2011 O OE1 . GLU A 1 258 ? 6.724 -4.672 3.026 1.00 2.00 ? 258 GLU A OE1 1 ATOM 2012 O OE2 . GLU A 1 258 ? 7.197 -5.151 5.115 1.00 2.14 ? 258 GLU A OE2 1 ATOM 2013 N N . GLN A 1 259 ? 9.637 -6.762 0.592 1.00 2.00 ? 259 GLN A N 1 ATOM 2014 C CA . GLN A 1 259 ? 9.334 -8.174 0.681 1.00 2.00 ? 259 GLN A CA 1 ATOM 2015 C C . GLN A 1 259 ? 9.275 -8.851 -0.679 1.00 3.25 ? 259 GLN A C 1 ATOM 2016 O O . GLN A 1 259 ? 8.876 -8.273 -1.699 1.00 2.87 ? 259 GLN A O 1 ATOM 2017 C CB . GLN A 1 259 ? 8.090 -8.369 1.524 1.00 2.00 ? 259 GLN A CB 1 ATOM 2018 C CG . GLN A 1 259 ? 6.853 -7.635 1.036 1.00 2.00 ? 259 GLN A CG 1 ATOM 2019 C CD . GLN A 1 259 ? 5.987 -8.554 0.215 1.00 2.28 ? 259 GLN A CD 1 ATOM 2020 O OE1 . GLN A 1 259 ? 6.197 -9.764 0.208 1.00 2.85 ? 259 GLN A OE1 1 ATOM 2021 N NE2 . GLN A 1 259 ? 4.963 -8.193 -0.555 1.00 2.00 ? 259 GLN A NE2 1 ATOM 2022 N N . ILE A 1 260 ? 9.729 -10.100 -0.698 1.00 2.38 ? 260 ILE A N 1 ATOM 2023 C CA . ILE A 1 260 ? 9.877 -10.822 -1.931 1.00 2.26 ? 260 ILE A CA 1 ATOM 2024 C C . ILE A 1 260 ? 8.684 -10.676 -2.818 1.00 2.00 ? 260 ILE A C 1 ATOM 2025 O O . ILE A 1 260 ? 8.800 -10.533 -4.036 1.00 2.10 ? 260 ILE A O 1 ATOM 2026 C CB . ILE A 1 260 ? 10.119 -12.320 -1.741 1.00 2.00 ? 260 ILE A CB 1 ATOM 2027 C CG1 . ILE A 1 260 ? 10.658 -12.926 -3.042 1.00 2.00 ? 260 ILE A CG1 1 ATOM 2028 C CG2 . ILE A 1 260 ? 8.834 -13.044 -1.335 1.00 2.49 ? 260 ILE A CG2 1 ATOM 2029 C CD1 . ILE A 1 260 ? 12.129 -13.282 -2.991 1.00 2.00 ? 260 ILE A CD1 1 ATOM 2030 N N . LEU A 1 261 ? 7.498 -10.714 -2.246 1.00 2.00 ? 261 LEU A N 1 ATOM 2031 C CA . LEU A 1 261 ? 6.284 -10.617 -3.017 1.00 2.00 ? 261 LEU A CA 1 ATOM 2032 C C . LEU A 1 261 ? 6.040 -9.264 -3.684 1.00 2.00 ? 261 LEU A C 1 ATOM 2033 O O . LEU A 1 261 ? 5.527 -9.215 -4.797 1.00 2.43 ? 261 LEU A O 1 ATOM 2034 C CB . LEU A 1 261 ? 5.103 -10.950 -2.115 1.00 2.00 ? 261 LEU A CB 1 ATOM 2035 C CG . LEU A 1 261 ? 4.430 -12.301 -2.337 1.00 2.00 ? 261 LEU A CG 1 ATOM 2036 C CD1 . LEU A 1 261 ? 5.115 -13.053 -3.462 1.00 2.00 ? 261 LEU A CD1 1 ATOM 2037 C CD2 . LEU A 1 261 ? 4.442 -13.118 -1.047 1.00 2.00 ? 261 LEU A CD2 1 ATOM 2038 N N . LEU A 1 262 ? 6.387 -8.170 -3.015 1.00 2.00 ? 262 LEU A N 1 ATOM 2039 C CA . LEU A 1 262 ? 6.195 -6.841 -3.594 1.00 2.00 ? 262 LEU A CA 1 ATOM 2040 C C . LEU A 1 262 ? 7.217 -6.591 -4.695 1.00 2.00 ? 262 LEU A C 1 ATOM 2041 O O . LEU A 1 262 ? 6.872 -6.141 -5.794 1.00 2.00 ? 262 LEU A O 1 ATOM 2042 C CB . LEU A 1 262 ? 6.334 -5.750 -2.526 1.00 2.00 ? 262 LEU A CB 1 ATOM 2043 C CG . LEU A 1 262 ? 6.438 -4.319 -3.074 1.00 2.00 ? 262 LEU A CG 1 ATOM 2044 C CD1 . LEU A 1 262 ? 5.272 -4.037 -4.009 1.00 2.00 ? 262 LEU A CD1 1 ATOM 2045 C CD2 . LEU A 1 262 ? 6.459 -3.322 -1.932 1.00 2.00 ? 262 LEU A CD2 1 ATOM 2046 N N . ALA A 1 263 ? 8.479 -6.882 -4.387 1.00 2.00 ? 263 ALA A N 1 ATOM 2047 C CA . ALA A 1 263 ? 9.557 -6.702 -5.346 1.00 2.00 ? 263 ALA A CA 1 ATOM 2048 C C . ALA A 1 263 ? 9.230 -7.497 -6.602 1.00 2.00 ? 263 ALA A C 1 ATOM 2049 O O . ALA A 1 263 ? 9.688 -7.167 -7.692 1.00 2.00 ? 263 ALA A O 1 ATOM 2050 C CB . ALA A 1 263 ? 10.872 -7.173 -4.749 1.00 2.00 ? 263 ALA A CB 1 ATOM 2051 N N . THR A 1 264 ? 8.427 -8.543 -6.437 1.00 2.03 ? 264 THR A N 1 ATOM 2052 C CA . THR A 1 264 ? 8.019 -9.389 -7.546 1.00 2.00 ? 264 THR A CA 1 ATOM 2053 C C . THR A 1 264 ? 7.099 -8.652 -8.515 1.00 2.21 ? 264 THR A C 1 ATOM 2054 O O . THR A 1 264 ? 7.449 -8.447 -9.680 1.00 2.93 ? 264 THR A O 1 ATOM 2055 C CB . THR A 1 264 ? 7.346 -10.648 -7.016 1.00 2.00 ? 264 THR A CB 1 ATOM 2056 O OG1 . THR A 1 264 ? 8.345 -11.458 -6.398 1.00 2.00 ? 264 THR A OG1 1 ATOM 2057 C CG2 . THR A 1 264 ? 6.688 -11.434 -8.118 1.00 2.00 ? 264 THR A CG2 1 ATOM 2058 N N . VAL A 1 265 ? 5.928 -8.234 -8.056 1.00 2.00 ? 265 VAL A N 1 ATOM 2059 C CA . VAL A 1 265 ? 5.043 -7.518 -8.958 1.00 2.00 ? 265 VAL A CA 1 ATOM 2060 C C . VAL A 1 265 ? 5.742 -6.271 -9.496 1.00 2.00 ? 265 VAL A C 1 ATOM 2061 O O . VAL A 1 265 ? 5.388 -5.744 -10.555 1.00 2.00 ? 265 VAL A O 1 ATOM 2062 C CB . VAL A 1 265 ? 3.744 -7.113 -8.261 1.00 2.00 ? 265 VAL A CB 1 ATOM 2063 C CG1 . VAL A 1 265 ? 2.870 -6.329 -9.214 1.00 2.00 ? 265 VAL A CG1 1 ATOM 2064 C CG2 . VAL A 1 265 ? 3.013 -8.347 -7.795 1.00 2.00 ? 265 VAL A CG2 1 ATOM 2065 N N . HIS A 1 266 ? 6.753 -5.804 -8.775 1.00 2.19 ? 266 HIS A N 1 ATOM 2066 C CA . HIS A 1 266 ? 7.469 -4.615 -9.210 1.00 3.02 ? 266 HIS A CA 1 ATOM 2067 C C . HIS A 1 266 ? 8.228 -4.841 -10.494 1.00 3.45 ? 266 HIS A C 1 ATOM 2068 O O . HIS A 1 266 ? 8.588 -3.887 -11.195 1.00 3.66 ? 266 HIS A O 1 ATOM 2069 C CB . HIS A 1 266 ? 8.423 -4.148 -8.131 1.00 2.00 ? 266 HIS A CB 1 ATOM 2070 C CG . HIS A 1 266 ? 8.103 -2.787 -7.615 1.00 2.00 ? 266 HIS A CG 1 ATOM 2071 N ND1 . HIS A 1 266 ? 8.366 -1.642 -8.333 1.00 2.00 ? 266 HIS A ND1 1 ATOM 2072 C CD2 . HIS A 1 266 ? 7.509 -2.387 -6.466 1.00 2.00 ? 266 HIS A CD2 1 ATOM 2073 C CE1 . HIS A 1 266 ? 7.950 -0.595 -7.645 1.00 2.28 ? 266 HIS A CE1 1 ATOM 2074 N NE2 . HIS A 1 266 ? 7.426 -1.020 -6.508 1.00 2.00 ? 266 HIS A NE2 1 ATOM 2075 N N . THR A 1 267 ? 8.465 -6.116 -10.789 1.00 3.40 ? 267 THR A N 1 ATOM 2076 C CA . THR A 1 267 ? 9.175 -6.526 -11.990 1.00 3.55 ? 267 THR A CA 1 ATOM 2077 C C . THR A 1 267 ? 8.165 -6.748 -13.111 1.00 3.22 ? 267 THR A C 1 ATOM 2078 O O . THR A 1 267 ? 8.381 -6.297 -14.237 1.00 3.63 ? 267 THR A O 1 ATOM 2079 C CB . THR A 1 267 ? 9.975 -7.809 -11.733 1.00 2.00 ? 267 THR A CB 1 ATOM 2080 O OG1 . THR A 1 267 ? 10.815 -7.599 -10.598 1.00 2.65 ? 267 THR A OG1 1 ATOM 2081 C CG2 . THR A 1 267 ? 10.848 -8.166 -12.931 1.00 2.00 ? 267 THR A CG2 1 ATOM 2082 N N . LEU A 1 268 ? 7.063 -7.435 -12.822 1.00 2.00 ? 268 LEU A N 1 ATOM 2083 C CA . LEU A 1 268 ? 6.063 -7.623 -13.862 1.00 2.38 ? 268 LEU A CA 1 ATOM 2084 C C . LEU A 1 268 ? 5.727 -6.253 -14.441 1.00 2.89 ? 268 LEU A C 1 ATOM 2085 O O . LEU A 1 268 ? 5.542 -6.091 -15.646 1.00 2.00 ? 268 LEU A O 1 ATOM 2086 C CB . LEU A 1 268 ? 4.804 -8.270 -13.298 1.00 3.69 ? 268 LEU A CB 1 ATOM 2087 C CG . LEU A 1 268 ? 4.713 -9.784 -13.437 1.00 4.50 ? 268 LEU A CG 1 ATOM 2088 C CD1 . LEU A 1 268 ? 5.975 -10.462 -12.912 1.00 5.42 ? 268 LEU A CD1 1 ATOM 2089 C CD2 . LEU A 1 268 ? 3.488 -10.240 -12.678 1.00 6.12 ? 268 LEU A CD2 1 ATOM 2090 N N . LEU A 1 269 ? 5.659 -5.259 -13.571 1.00 2.04 ? 269 LEU A N 1 ATOM 2091 C CA . LEU A 1 269 ? 5.372 -3.917 -14.022 1.00 2.46 ? 269 LEU A CA 1 ATOM 2092 C C . LEU A 1 269 ? 6.487 -3.448 -14.958 1.00 3.33 ? 269 LEU A C 1 ATOM 2093 O O . LEU A 1 269 ? 6.246 -3.103 -16.127 1.00 2.00 ? 269 LEU A O 1 ATOM 2094 C CB . LEU A 1 269 ? 5.272 -3.000 -12.813 1.00 2.19 ? 269 LEU A CB 1 ATOM 2095 C CG . LEU A 1 269 ? 3.869 -2.462 -12.551 1.00 2.82 ? 269 LEU A CG 1 ATOM 2096 C CD1 . LEU A 1 269 ? 2.773 -3.530 -12.777 1.00 2.00 ? 269 LEU A CD1 1 ATOM 2097 C CD2 . LEU A 1 269 ? 3.857 -1.951 -11.128 1.00 2.23 ? 269 LEU A CD2 1 ATOM 2098 N N . LEU A 1 270 ? 7.710 -3.450 -14.432 1.00 2.55 ? 270 LEU A N 1 ATOM 2099 C CA . LEU A 1 270 ? 8.873 -3.031 -15.192 1.00 2.68 ? 270 LEU A CA 1 ATOM 2100 C C . LEU A 1 270 ? 8.935 -3.726 -16.544 1.00 3.21 ? 270 LEU A C 1 ATOM 2101 O O . LEU A 1 270 ? 9.286 -3.120 -17.552 1.00 4.58 ? 270 LEU A O 1 ATOM 2102 C CB . LEU A 1 270 ? 10.148 -3.342 -14.420 1.00 2.02 ? 270 LEU A CB 1 ATOM 2103 C CG . LEU A 1 270 ? 11.415 -2.922 -15.153 1.00 2.00 ? 270 LEU A CG 1 ATOM 2104 C CD1 . LEU A 1 270 ? 11.477 -1.413 -15.194 1.00 2.00 ? 270 LEU A CD1 1 ATOM 2105 C CD2 . LEU A 1 270 ? 12.626 -3.484 -14.455 1.00 2.65 ? 270 LEU A CD2 1 ATOM 2106 N N . ARG A 1 271 ? 8.600 -5.007 -16.566 1.00 3.11 ? 271 ARG A N 1 ATOM 2107 C CA . ARG A 1 271 ? 8.629 -5.752 -17.810 1.00 2.91 ? 271 ARG A CA 1 ATOM 2108 C C . ARG A 1 271 ? 7.511 -5.319 -18.738 1.00 2.89 ? 271 ARG A C 1 ATOM 2109 O O . ARG A 1 271 ? 7.686 -5.275 -19.957 1.00 2.65 ? 271 ARG A O 1 ATOM 2110 C CB . ARG A 1 271 ? 8.510 -7.240 -17.529 1.00 2.19 ? 271 ARG A CB 1 ATOM 2111 C CG . ARG A 1 271 ? 9.665 -7.777 -16.731 1.00 2.00 ? 271 ARG A CG 1 ATOM 2112 C CD . ARG A 1 271 ? 9.534 -9.252 -16.595 1.00 2.00 ? 271 ARG A CD 1 ATOM 2113 N NE . ARG A 1 271 ? 10.668 -9.828 -15.897 1.00 2.00 ? 271 ARG A NE 1 ATOM 2114 C CZ . ARG A 1 271 ? 10.769 -11.119 -15.621 1.00 2.12 ? 271 ARG A CZ 1 ATOM 2115 N NH1 . ARG A 1 271 ? 9.802 -11.951 -15.986 1.00 3.06 ? 271 ARG A NH1 1 ATOM 2116 N NH2 . ARG A 1 271 ? 11.830 -11.581 -14.989 1.00 3.05 ? 271 ARG A NH2 1 ATOM 2117 N N . GLU A 1 272 ? 6.361 -4.995 -18.156 1.00 3.60 ? 272 GLU A N 1 ATOM 2118 C CA . GLU A 1 272 ? 5.204 -4.566 -18.934 1.00 3.07 ? 272 GLU A CA 1 ATOM 2119 C C . GLU A 1 272 ? 5.565 -3.396 -19.821 1.00 2.09 ? 272 GLU A C 1 ATOM 2120 O O . GLU A 1 272 ? 5.199 -3.360 -20.993 1.00 2.00 ? 272 GLU A O 1 ATOM 2121 C CB . GLU A 1 272 ? 4.051 -4.180 -18.002 1.00 2.44 ? 272 GLU A CB 1 ATOM 2122 C CG . GLU A 1 272 ? 2.742 -3.877 -18.702 1.00 2.00 ? 272 GLU A CG 1 ATOM 2123 C CD . GLU A 1 272 ? 2.475 -4.804 -19.866 1.00 3.76 ? 272 GLU A CD 1 ATOM 2124 O OE1 . GLU A 1 272 ? 3.241 -5.770 -20.051 1.00 2.65 ? 272 GLU A OE1 1 ATOM 2125 O OE2 . GLU A 1 272 ? 1.494 -4.569 -20.605 1.00 6.19 ? 272 GLU A OE2 1 ATOM 2126 N N . HIS A 1 273 ? 6.296 -2.446 -19.245 1.00 2.73 ? 273 HIS A N 1 ATOM 2127 C CA . HIS A 1 273 ? 6.725 -1.256 -19.964 1.00 3.30 ? 273 HIS A CA 1 ATOM 2128 C C . HIS A 1 273 ? 7.611 -1.581 -21.159 1.00 4.48 ? 273 HIS A C 1 ATOM 2129 O O . HIS A 1 273 ? 7.239 -1.294 -22.297 1.00 7.71 ? 273 HIS A O 1 ATOM 2130 C CB . HIS A 1 273 ? 7.471 -0.322 -19.030 1.00 2.00 ? 273 HIS A CB 1 ATOM 2131 C CG . HIS A 1 273 ? 8.068 0.861 -19.718 1.00 2.00 ? 273 HIS A CG 1 ATOM 2132 N ND1 . HIS A 1 273 ? 7.595 2.142 -19.541 1.00 2.00 ? 273 HIS A ND1 1 ATOM 2133 C CD2 . HIS A 1 273 ? 9.117 0.963 -20.566 1.00 2.41 ? 273 HIS A CD2 1 ATOM 2134 C CE1 . HIS A 1 273 ? 8.328 2.984 -20.246 1.00 2.00 ? 273 HIS A CE1 1 ATOM 2135 N NE2 . HIS A 1 273 ? 9.259 2.293 -20.878 1.00 2.19 ? 273 HIS A NE2 1 ATOM 2136 N N . ASN A 1 274 ? 8.783 -2.162 -20.913 1.00 3.39 ? 274 ASN A N 1 ATOM 2137 C CA . ASN A 1 274 ? 9.685 -2.506 -22.012 1.00 2.00 ? 274 ASN A CA 1 ATOM 2138 C C . ASN A 1 274 ? 8.963 -3.211 -23.147 1.00 2.00 ? 274 ASN A C 1 ATOM 2139 O O . ASN A 1 274 ? 9.328 -3.069 -24.305 1.00 2.00 ? 274 ASN A O 1 ATOM 2140 C CB . ASN A 1 274 ? 10.811 -3.417 -21.541 1.00 2.00 ? 274 ASN A CB 1 ATOM 2141 C CG . ASN A 1 274 ? 11.789 -2.714 -20.644 1.00 2.13 ? 274 ASN A CG 1 ATOM 2142 O OD1 . ASN A 1 274 ? 11.858 -1.484 -20.614 1.00 2.00 ? 274 ASN A OD1 1 ATOM 2143 N ND2 . ASN A 1 274 ? 12.573 -3.495 -19.913 1.00 3.68 ? 274 ASN A ND2 1 ATOM 2144 N N . ARG A 1 275 ? 7.946 -3.987 -22.812 1.00 2.00 ? 275 ARG A N 1 ATOM 2145 C CA . ARG A 1 275 ? 7.206 -4.706 -23.827 1.00 2.00 ? 275 ARG A CA 1 ATOM 2146 C C . ARG A 1 275 ? 6.513 -3.682 -24.703 1.00 2.00 ? 275 ARG A C 1 ATOM 2147 O O . ARG A 1 275 ? 6.757 -3.611 -25.896 1.00 2.00 ? 275 ARG A O 1 ATOM 2148 C CB . ARG A 1 275 ? 6.177 -5.610 -23.164 1.00 2.00 ? 275 ARG A CB 1 ATOM 2149 C CG . ARG A 1 275 ? 5.696 -6.754 -24.012 1.00 2.00 ? 275 ARG A CG 1 ATOM 2150 C CD . ARG A 1 275 ? 4.427 -7.325 -23.414 1.00 4.54 ? 275 ARG A CD 1 ATOM 2151 N NE . ARG A 1 275 ? 3.264 -6.925 -24.196 1.00 6.59 ? 275 ARG A NE 1 ATOM 2152 C CZ . ARG A 1 275 ? 2.064 -6.658 -23.691 1.00 6.80 ? 275 ARG A CZ 1 ATOM 2153 N NH1 . ARG A 1 275 ? 1.846 -6.740 -22.388 1.00 7.45 ? 275 ARG A NH1 1 ATOM 2154 N NH2 . ARG A 1 275 ? 1.077 -6.314 -24.503 1.00 8.03 ? 275 ARG A NH2 1 ATOM 2155 N N . LEU A 1 276 ? 5.655 -2.879 -24.083 1.00 2.21 ? 276 LEU A N 1 ATOM 2156 C CA . LEU A 1 276 ? 4.890 -1.846 -24.769 1.00 2.00 ? 276 LEU A CA 1 ATOM 2157 C C . LEU A 1 276 ? 5.762 -0.963 -25.637 1.00 2.00 ? 276 LEU A C 1 ATOM 2158 O O . LEU A 1 276 ? 5.466 -0.770 -26.808 1.00 2.75 ? 276 LEU A O 1 ATOM 2159 C CB . LEU A 1 276 ? 4.143 -1.000 -23.741 1.00 2.00 ? 276 LEU A CB 1 ATOM 2160 C CG . LEU A 1 276 ? 2.816 -1.508 -23.168 1.00 2.00 ? 276 LEU A CG 1 ATOM 2161 C CD1 . LEU A 1 276 ? 2.814 -3.014 -23.061 1.00 2.60 ? 276 LEU A CD1 1 ATOM 2162 C CD2 . LEU A 1 276 ? 2.593 -0.867 -21.811 1.00 2.00 ? 276 LEU A CD2 1 ATOM 2163 N N . ALA A 1 277 ? 6.828 -0.418 -25.066 1.00 2.00 ? 277 ALA A N 1 ATOM 2164 C CA . ALA A 1 277 ? 7.737 0.427 -25.826 1.00 2.00 ? 277 ALA A CA 1 ATOM 2165 C C . ALA A 1 277 ? 8.217 -0.344 -27.060 1.00 2.89 ? 277 ALA A C 1 ATOM 2166 O O . ALA A 1 277 ? 8.118 0.124 -28.192 1.00 3.09 ? 277 ALA A O 1 ATOM 2167 C CB . ALA A 1 277 ? 8.920 0.815 -24.966 1.00 2.00 ? 277 ALA A CB 1 ATOM 2168 N N . ARG A 1 278 ? 8.732 -1.541 -26.831 1.00 4.29 ? 278 ARG A N 1 ATOM 2169 C CA . ARG A 1 278 ? 9.220 -2.372 -27.920 1.00 4.67 ? 278 ARG A CA 1 ATOM 2170 C C . ARG A 1 278 ? 8.094 -2.532 -28.930 1.00 3.78 ? 278 ARG A C 1 ATOM 2171 O O . ARG A 1 278 ? 8.217 -2.129 -30.081 1.00 2.43 ? 278 ARG A O 1 ATOM 2172 C CB . ARG A 1 278 ? 9.656 -3.735 -27.371 1.00 5.73 ? 278 ARG A CB 1 ATOM 2173 C CG . ARG A 1 278 ? 10.902 -4.270 -28.023 1.00 7.61 ? 278 ARG A CG 1 ATOM 2174 C CD . ARG A 1 278 ? 11.453 -5.452 -27.273 1.00 10.29 ? 278 ARG A CD 1 ATOM 2175 N NE . ARG A 1 278 ? 12.084 -5.082 -26.009 1.00 13.32 ? 278 ARG A NE 1 ATOM 2176 C CZ . ARG A 1 278 ? 11.608 -5.415 -24.812 1.00 15.59 ? 278 ARG A CZ 1 ATOM 2177 N NH1 . ARG A 1 278 ? 10.486 -6.117 -24.713 1.00 16.71 ? 278 ARG A NH1 1 ATOM 2178 N NH2 . ARG A 1 278 ? 12.273 -5.085 -23.711 1.00 16.67 ? 278 ARG A NH2 1 ATOM 2179 N N . GLU A 1 279 ? 6.994 -3.112 -28.471 1.00 5.50 ? 279 GLU A N 1 ATOM 2180 C CA . GLU A 1 279 ? 5.816 -3.338 -29.290 1.00 7.11 ? 279 GLU A CA 1 ATOM 2181 C C . GLU A 1 279 ? 5.414 -2.114 -30.100 1.00 9.59 ? 279 GLU A C 1 ATOM 2182 O O . GLU A 1 279 ? 5.243 -2.199 -31.316 1.00 11.85 ? 279 GLU A O 1 ATOM 2183 C CB . GLU A 1 279 ? 4.644 -3.714 -28.410 1.00 9.84 ? 279 GLU A CB 1 ATOM 2184 C CG . GLU A 1 279 ? 3.386 -3.933 -29.191 1.00 14.47 ? 279 GLU A CG 1 ATOM 2185 C CD . GLU A 1 279 ? 3.325 -5.322 -29.773 1.00 17.45 ? 279 GLU A CD 1 ATOM 2186 O OE1 . GLU A 1 279 ? 4.329 -5.747 -30.387 1.00 19.07 ? 279 GLU A OE1 1 ATOM 2187 O OE2 . GLU A 1 279 ? 2.272 -5.986 -29.610 1.00 20.35 ? 279 GLU A OE2 1 ATOM 2188 N N . LEU A 1 280 ? 5.229 -0.987 -29.415 1.00 8.95 ? 280 LEU A N 1 ATOM 2189 C CA . LEU A 1 280 ? 4.845 0.261 -30.073 1.00 8.44 ? 280 LEU A CA 1 ATOM 2190 C C . LEU A 1 280 ? 5.844 0.617 -31.162 1.00 9.61 ? 280 LEU A C 1 ATOM 2191 O O . LEU A 1 280 ? 5.459 1.042 -32.246 1.00 10.09 ? 280 LEU A O 1 ATOM 2192 C CB . LEU A 1 280 ? 4.790 1.415 -29.069 1.00 6.74 ? 280 LEU A CB 1 ATOM 2193 C CG . LEU A 1 280 ? 3.791 1.333 -27.917 1.00 6.15 ? 280 LEU A CG 1 ATOM 2194 C CD1 . LEU A 1 280 ? 4.275 2.238 -26.802 1.00 4.44 ? 280 LEU A CD1 1 ATOM 2195 C CD2 . LEU A 1 280 ? 2.388 1.710 -28.386 1.00 4.94 ? 280 LEU A CD2 1 ATOM 2196 N N . LYS A 1 281 ? 7.130 0.442 -30.876 1.00 10.16 ? 281 LYS A N 1 ATOM 2197 C CA . LYS A 1 281 ? 8.158 0.768 -31.854 1.00 11.17 ? 281 LYS A CA 1 ATOM 2198 C C . LYS A 1 281 ? 7.965 0.119 -33.219 1.00 12.45 ? 281 LYS A C 1 ATOM 2199 O O . LYS A 1 281 ? 8.153 0.779 -34.234 1.00 11.52 ? 281 LYS A O 1 ATOM 2200 C CB . LYS A 1 281 ? 9.538 0.398 -31.325 1.00 12.20 ? 281 LYS A CB 1 ATOM 2201 C CG . LYS A 1 281 ? 10.631 0.460 -32.386 1.00 11.92 ? 281 LYS A CG 1 ATOM 2202 C CD . LYS A 1 281 ? 10.905 1.879 -32.818 1.00 12.04 ? 281 LYS A CD 1 ATOM 2203 C CE . LYS A 1 281 ? 12.209 1.974 -33.584 1.00 11.72 ? 281 LYS A CE 1 ATOM 2204 N NZ . LYS A 1 281 ? 12.621 3.399 -33.729 1.00 12.62 ? 281 LYS A NZ 1 ATOM 2205 N N . ARG A 1 282 ? 7.605 -1.164 -33.265 1.00 16.06 ? 282 ARG A N 1 ATOM 2206 C CA . ARG A 1 282 ? 7.427 -1.800 -34.568 1.00 19.60 ? 282 ARG A CA 1 ATOM 2207 C C . ARG A 1 282 ? 6.159 -1.372 -35.273 1.00 19.42 ? 282 ARG A C 1 ATOM 2208 O O . ARG A 1 282 ? 6.140 -1.275 -36.501 1.00 20.53 ? 282 ARG A O 1 ATOM 2209 C CB . ARG A 1 282 ? 7.499 -3.333 -34.490 1.00 22.85 ? 282 ARG A CB 1 ATOM 2210 C CG . ARG A 1 282 ? 6.580 -4.055 -33.526 1.00 28.27 ? 282 ARG A CG 1 ATOM 2211 C CD . ARG A 1 282 ? 6.901 -5.556 -33.625 1.00 33.41 ? 282 ARG A CD 1 ATOM 2212 N NE . ARG A 1 282 ? 6.542 -6.324 -32.434 1.00 38.99 ? 282 ARG A NE 1 ATOM 2213 C CZ . ARG A 1 282 ? 7.128 -7.467 -32.078 1.00 40.79 ? 282 ARG A CZ 1 ATOM 2214 N NH1 . ARG A 1 282 ? 8.104 -7.974 -32.824 1.00 42.61 ? 282 ARG A NH1 1 ATOM 2215 N NH2 . ARG A 1 282 ? 6.744 -8.098 -30.972 1.00 42.16 ? 282 ARG A NH2 1 ATOM 2216 N N . LEU A 1 283 ? 5.100 -1.109 -34.514 1.00 18.77 ? 283 LEU A N 1 ATOM 2217 C CA . LEU A 1 283 ? 3.866 -0.647 -35.137 1.00 16.94 ? 283 LEU A CA 1 ATOM 2218 C C . LEU A 1 283 ? 4.032 0.810 -35.558 1.00 15.58 ? 283 LEU A C 1 ATOM 2219 O O . LEU A 1 283 ? 3.358 1.279 -36.470 1.00 15.76 ? 283 LEU A O 1 ATOM 2220 C CB . LEU A 1 283 ? 2.676 -0.772 -34.187 1.00 17.55 ? 283 LEU A CB 1 ATOM 2221 C CG . LEU A 1 283 ? 1.675 -1.874 -34.562 1.00 19.93 ? 283 LEU A CG 1 ATOM 2222 C CD1 . LEU A 1 283 ? 0.347 -1.592 -33.870 1.00 20.36 ? 283 LEU A CD1 1 ATOM 2223 C CD2 . LEU A 1 283 ? 1.462 -1.923 -36.082 1.00 20.30 ? 283 LEU A CD2 1 ATOM 2224 N N . ASN A 1 284 ? 4.942 1.513 -34.889 1.00 13.91 ? 284 ASN A N 1 ATOM 2225 C CA . ASN A 1 284 ? 5.225 2.917 -35.177 1.00 12.04 ? 284 ASN A CA 1 ATOM 2226 C C . ASN A 1 284 ? 6.730 3.119 -35.310 1.00 11.02 ? 284 ASN A C 1 ATOM 2227 O O . ASN A 1 284 ? 7.367 3.752 -34.467 1.00 11.31 ? 284 ASN A O 1 ATOM 2228 C CB . ASN A 1 284 ? 4.686 3.813 -34.058 1.00 12.72 ? 284 ASN A CB 1 ATOM 2229 C CG . ASN A 1 284 ? 3.178 3.980 -34.113 1.00 13.31 ? 284 ASN A CG 1 ATOM 2230 O OD1 . ASN A 1 284 ? 2.434 3.008 -34.274 1.00 14.76 ? 284 ASN A OD1 1 ATOM 2231 N ND2 . ASN A 1 284 ? 2.717 5.217 -33.968 1.00 13.09 ? 284 ASN A ND2 1 ATOM 2232 N N . PRO A 1 285 ? 7.316 2.580 -36.384 1.00 10.94 ? 285 PRO A N 1 ATOM 2233 C CA . PRO A 1 285 ? 8.747 2.650 -36.708 1.00 12.63 ? 285 PRO A CA 1 ATOM 2234 C C . PRO A 1 285 ? 9.464 4.004 -36.524 1.00 11.51 ? 285 PRO A C 1 ATOM 2235 O O . PRO A 1 285 ? 10.594 4.069 -36.031 1.00 10.27 ? 285 PRO A O 1 ATOM 2236 C CB . PRO A 1 285 ? 8.779 2.167 -38.158 1.00 12.03 ? 285 PRO A CB 1 ATOM 2237 C CG . PRO A 1 285 ? 7.704 1.117 -38.165 1.00 11.81 ? 285 PRO A CG 1 ATOM 2238 C CD . PRO A 1 285 ? 6.586 1.789 -37.394 1.00 11.13 ? 285 PRO A CD 1 ATOM 2239 N N . HIS A 1 286 ? 8.794 5.081 -36.905 1.00 12.54 ? 286 HIS A N 1 ATOM 2240 C CA . HIS A 1 286 ? 9.411 6.414 -36.868 1.00 13.77 ? 286 HIS A CA 1 ATOM 2241 C C . HIS A 1 286 ? 9.222 7.180 -35.536 1.00 14.16 ? 286 HIS A C 1 ATOM 2242 O O . HIS A 1 286 ? 9.603 8.352 -35.455 1.00 15.88 ? 286 HIS A O 1 ATOM 2243 C CB . HIS A 1 286 ? 8.832 7.273 -37.986 1.00 14.30 ? 286 HIS A CB 1 ATOM 2244 C CG . HIS A 1 286 ? 7.290 7.400 -37.787 1.00 15.49 ? 286 HIS A CG 1 ATOM 2245 N ND1 . HIS A 1 286 ? 6.439 6.328 -37.956 1.00 15.89 ? 286 HIS A ND1 1 ATOM 2246 C CD2 . HIS A 1 286 ? 6.512 8.447 -37.424 1.00 16.49 ? 286 HIS A CD2 1 ATOM 2247 C CE1 . HIS A 1 286 ? 5.200 6.710 -37.704 1.00 17.41 ? 286 HIS A CE1 1 ATOM 2248 N NE2 . HIS A 1 286 ? 5.216 7.991 -37.378 1.00 18.07 ? 286 HIS A NE2 1 ATOM 2249 N N . TRP A 1 287 ? 8.654 6.574 -34.493 1.00 13.74 ? 287 TRP A N 1 ATOM 2250 C CA . TRP A 1 287 ? 8.455 7.304 -33.226 1.00 12.49 ? 287 TRP A CA 1 ATOM 2251 C C . TRP A 1 287 ? 9.765 7.593 -32.527 1.00 11.64 ? 287 TRP A C 1 ATOM 2252 O O . TRP A 1 287 ? 10.841 7.162 -32.954 1.00 12.55 ? 287 TRP A O 1 ATOM 2253 C CB . TRP A 1 287 ? 7.514 6.589 -32.270 1.00 10.41 ? 287 TRP A CB 1 ATOM 2254 C CG . TRP A 1 287 ? 6.104 7.052 -32.452 1.00 10.08 ? 287 TRP A CG 1 ATOM 2255 C CD1 . TRP A 1 287 ? 5.636 7.924 -33.390 1.00 11.10 ? 287 TRP A CD1 1 ATOM 2256 C CD2 . TRP A 1 287 ? 4.956 6.637 -31.689 1.00 10.51 ? 287 TRP A CD2 1 ATOM 2257 N NE1 . TRP A 1 287 ? 4.275 8.081 -33.264 1.00 11.54 ? 287 TRP A NE1 1 ATOM 2258 C CE2 . TRP A 1 287 ? 3.832 7.303 -32.229 1.00 10.69 ? 287 TRP A CE2 1 ATOM 2259 C CE3 . TRP A 1 287 ? 4.768 5.770 -30.606 1.00 10.71 ? 287 TRP A CE3 1 ATOM 2260 C CZ2 . TRP A 1 287 ? 2.538 7.130 -31.724 1.00 10.58 ? 287 TRP A CZ2 1 ATOM 2261 C CZ3 . TRP A 1 287 ? 3.476 5.597 -30.103 1.00 10.39 ? 287 TRP A CZ3 1 ATOM 2262 C CH2 . TRP A 1 287 ? 2.382 6.276 -30.664 1.00 11.10 ? 287 TRP A CH2 1 ATOM 2263 N N . ASP A 1 288 ? 9.686 8.313 -31.433 1.00 11.43 ? 288 ASP A N 1 ATOM 2264 C CA . ASP A 1 288 ? 10.875 8.762 -30.743 1.00 11.27 ? 288 ASP A CA 1 ATOM 2265 C C . ASP A 1 288 ? 11.236 7.945 -29.523 1.00 9.71 ? 288 ASP A C 1 ATOM 2266 O O . ASP A 1 288 ? 10.362 7.331 -28.902 1.00 7.87 ? 288 ASP A O 1 ATOM 2267 C CB . ASP A 1 288 ? 10.661 10.215 -30.318 1.00 14.62 ? 288 ASP A CB 1 ATOM 2268 C CG . ASP A 1 288 ? 11.941 10.979 -30.281 1.00 17.66 ? 288 ASP A CG 1 ATOM 2269 O OD1 . ASP A 1 288 ? 12.985 10.429 -30.663 1.00 18.94 ? 288 ASP A OD1 1 ATOM 2270 O OD2 . ASP A 1 288 ? 11.898 12.155 -29.858 1.00 18.82 ? 288 ASP A OD2 1 ATOM 2271 N N . GLY A 1 289 ? 12.506 7.939 -29.178 1.00 9.78 ? 289 GLY A N 1 ATOM 2272 C CA . GLY A 1 289 ? 12.919 7.183 -28.031 1.00 10.55 ? 289 GLY A CA 1 ATOM 2273 C C . GLY A 1 289 ? 12.047 7.662 -26.917 1.00 11.43 ? 289 GLY A C 1 ATOM 2274 O O . GLY A 1 289 ? 11.517 6.925 -26.078 1.00 13.61 ? 289 GLY A O 1 ATOM 2275 N N . GLU A 1 290 ? 11.939 9.010 -26.960 1.00 10.58 ? 290 GLU A N 1 ATOM 2276 C CA . GLU A 1 290 ? 11.121 9.718 -25.987 1.00 8.99 ? 290 GLU A CA 1 ATOM 2277 C C . GLU A 1 290 ? 9.633 9.495 -26.191 1.00 7.58 ? 290 GLU A C 1 ATOM 2278 O O . GLU A 1 290 ? 8.965 9.206 -25.193 1.00 7.91 ? 290 GLU A O 1 ATOM 2279 C CB . GLU A 1 290 ? 11.477 11.225 -25.826 1.00 10.21 ? 290 GLU A CB 1 ATOM 2280 C CG . GLU A 1 290 ? 10.462 12.080 -25.005 1.00 12.52 ? 290 GLU A CG 1 ATOM 2281 C CD . GLU A 1 290 ? 10.645 12.195 -23.472 1.00 13.62 ? 290 GLU A CD 1 ATOM 2282 O OE1 . GLU A 1 290 ? 11.220 11.268 -22.868 1.00 15.61 ? 290 GLU A OE1 1 ATOM 2283 O OE2 . GLU A 1 290 ? 10.199 13.219 -22.897 1.00 15.67 ? 290 GLU A OE2 1 ATOM 2284 N N . LYS A 1 291 ? 9.096 9.598 -27.407 1.00 5.49 ? 291 LYS A N 1 ATOM 2285 C CA . LYS A 1 291 ? 7.651 9.329 -27.635 1.00 4.04 ? 291 LYS A CA 1 ATOM 2286 C C . LYS A 1 291 ? 7.311 7.928 -27.091 1.00 3.57 ? 291 LYS A C 1 ATOM 2287 O O . LYS A 1 291 ? 6.206 7.708 -26.560 1.00 2.00 ? 291 LYS A O 1 ATOM 2288 C CB . LYS A 1 291 ? 7.339 9.403 -29.136 1.00 2.59 ? 291 LYS A CB 1 ATOM 2289 C CG . LYS A 1 291 ? 5.851 9.427 -29.450 1.00 2.00 ? 291 LYS A CG 1 ATOM 2290 C CD . LYS A 1 291 ? 5.246 10.737 -29.013 1.00 2.25 ? 291 LYS A CD 1 ATOM 2291 C CE . LYS A 1 291 ? 3.894 10.927 -29.663 1.00 4.21 ? 291 LYS A CE 1 ATOM 2292 N NZ . LYS A 1 291 ? 2.955 9.827 -29.307 1.00 6.53 ? 291 LYS A NZ 1 ATOM 2293 N N . LEU A 1 292 ? 8.242 6.990 -27.252 1.00 3.78 ? 292 LEU A N 1 ATOM 2294 C CA . LEU A 1 292 ? 8.035 5.606 -26.771 1.00 4.32 ? 292 LEU A CA 1 ATOM 2295 C C . LEU A 1 292 ? 7.636 5.632 -25.281 1.00 5.89 ? 292 LEU A C 1 ATOM 2296 O O . LEU A 1 292 ? 6.571 5.096 -24.945 1.00 7.64 ? 292 LEU A O 1 ATOM 2297 C CB . LEU A 1 292 ? 9.244 4.720 -27.136 1.00 3.57 ? 292 LEU A CB 1 ATOM 2298 C CG . LEU A 1 292 ? 9.207 4.074 -28.558 1.00 3.20 ? 292 LEU A CG 1 ATOM 2299 C CD1 . LEU A 1 292 ? 8.168 4.755 -29.447 1.00 2.00 ? 292 LEU A CD1 1 ATOM 2300 C CD2 . LEU A 1 292 ? 10.585 4.127 -29.211 1.00 3.43 ? 292 LEU A CD2 1 ATOM 2301 N N . TYR A 1 293 ? 8.438 6.251 -24.359 1.00 4.29 ? 293 TYR A N 1 ATOM 2302 C CA . TYR A 1 293 ? 8.062 6.407 -22.920 1.00 3.64 ? 293 TYR A CA 1 ATOM 2303 C C . TYR A 1 293 ? 6.865 7.348 -22.921 1.00 4.18 ? 293 TYR A C 1 ATOM 2304 O O . TYR A 1 293 ? 6.675 8.112 -23.864 1.00 5.79 ? 293 TYR A O 1 ATOM 2305 C CB . TYR A 1 293 ? 9.319 6.901 -22.131 1.00 3.74 ? 293 TYR A CB 1 ATOM 2306 C CG . TYR A 1 293 ? 9.285 7.440 -20.697 1.00 4.42 ? 293 TYR A CG 1 ATOM 2307 C CD1 . TYR A 1 293 ? 9.543 6.607 -19.616 1.00 5.54 ? 293 TYR A CD1 1 ATOM 2308 C CD2 . TYR A 1 293 ? 9.068 8.799 -20.420 1.00 6.83 ? 293 TYR A CD2 1 ATOM 2309 C CE1 . TYR A 1 293 ? 9.594 7.076 -18.323 1.00 7.27 ? 293 TYR A CE1 1 ATOM 2310 C CE2 . TYR A 1 293 ? 9.145 9.285 -19.127 1.00 8.59 ? 293 TYR A CE2 1 ATOM 2311 C CZ . TYR A 1 293 ? 9.410 8.433 -18.068 1.00 8.41 ? 293 TYR A CZ 1 ATOM 2312 O OH . TYR A 1 293 ? 9.499 8.938 -16.790 1.00 10.73 ? 293 TYR A OH 1 ATOM 2313 N N . GLN A 1 294 ? 6.062 7.283 -21.930 1.00 4.46 ? 294 GLN A N 1 ATOM 2314 C CA . GLN A 1 294 ? 4.810 8.048 -21.858 1.00 4.17 ? 294 GLN A CA 1 ATOM 2315 C C . GLN A 1 294 ? 3.742 7.734 -22.944 1.00 4.99 ? 294 GLN A C 1 ATOM 2316 O O . GLN A 1 294 ? 2.595 8.160 -22.774 1.00 4.95 ? 294 GLN A O 1 ATOM 2317 C CB . GLN A 1 294 ? 5.015 9.601 -21.727 1.00 3.57 ? 294 GLN A CB 1 ATOM 2318 C CG . GLN A 1 294 ? 6.392 10.183 -22.064 1.00 4.08 ? 294 GLN A CG 1 ATOM 2319 C CD . GLN A 1 294 ? 6.900 11.243 -21.103 1.00 3.24 ? 294 GLN A CD 1 ATOM 2320 O OE1 . GLN A 1 294 ? 6.202 11.652 -20.166 1.00 5.69 ? 294 GLN A OE1 1 ATOM 2321 N NE2 . GLN A 1 294 ? 8.075 11.829 -21.155 1.00 3.02 ? 294 GLN A NE2 1 ATOM 2322 N N . GLU A 1 295 ? 4.010 7.005 -24.064 1.00 3.69 ? 295 GLU A N 1 ATOM 2323 C CA . GLU A 1 295 ? 2.907 6.528 -24.840 1.00 2.10 ? 295 GLU A CA 1 ATOM 2324 C C . GLU A 1 295 ? 2.667 5.191 -24.203 1.00 2.00 ? 295 GLU A C 1 ATOM 2325 O O . GLU A 1 295 ? 1.556 4.676 -24.130 1.00 3.56 ? 295 GLU A O 1 ATOM 2326 C CB . GLU A 1 295 ? 3.249 6.422 -26.325 1.00 2.49 ? 295 GLU A CB 1 ATOM 2327 C CG . GLU A 1 295 ? 2.648 7.511 -27.190 1.00 4.03 ? 295 GLU A CG 1 ATOM 2328 C CD . GLU A 1 295 ? 1.130 7.498 -27.167 1.00 5.97 ? 295 GLU A CD 1 ATOM 2329 O OE1 . GLU A 1 295 ? 0.549 6.474 -26.733 1.00 7.20 ? 295 GLU A OE1 1 ATOM 2330 O OE2 . GLU A 1 295 ? 0.518 8.497 -27.597 1.00 5.15 ? 295 GLU A OE2 1 ATOM 2331 N N . ALA A 1 296 ? 3.793 4.667 -23.741 1.00 2.00 ? 296 ALA A N 1 ATOM 2332 C CA . ALA A 1 296 ? 3.697 3.390 -23.046 1.00 2.00 ? 296 ALA A CA 1 ATOM 2333 C C . ALA A 1 296 ? 3.303 3.707 -21.617 1.00 2.81 ? 296 ALA A C 1 ATOM 2334 O O . ALA A 1 296 ? 2.341 3.145 -21.088 1.00 4.62 ? 296 ALA A O 1 ATOM 2335 C CB . ALA A 1 296 ? 5.031 2.685 -23.062 1.00 2.00 ? 296 ALA A CB 1 ATOM 2336 N N . ARG A 1 297 ? 4.064 4.609 -20.998 1.00 2.75 ? 297 ARG A N 1 ATOM 2337 C CA . ARG A 1 297 ? 3.793 5.042 -19.632 1.00 2.00 ? 297 ARG A CA 1 ATOM 2338 C C . ARG A 1 297 ? 2.323 5.447 -19.491 1.00 3.62 ? 297 ARG A C 1 ATOM 2339 O O . ARG A 1 297 ? 1.751 5.379 -18.395 1.00 4.49 ? 297 ARG A O 1 ATOM 2340 C CB . ARG A 1 297 ? 4.695 6.221 -19.259 1.00 2.00 ? 297 ARG A CB 1 ATOM 2341 C CG . ARG A 1 297 ? 4.267 6.995 -18.011 1.00 2.00 ? 297 ARG A CG 1 ATOM 2342 C CD . ARG A 1 297 ? 5.460 7.727 -17.403 1.00 2.15 ? 297 ARG A CD 1 ATOM 2343 N NE . ARG A 1 297 ? 5.110 8.627 -16.306 1.00 2.31 ? 297 ARG A NE 1 ATOM 2344 C CZ . ARG A 1 297 ? 4.741 9.894 -16.467 1.00 2.32 ? 297 ARG A CZ 1 ATOM 2345 N NH1 . ARG A 1 297 ? 4.670 10.416 -17.682 1.00 3.22 ? 297 ARG A NH1 1 ATOM 2346 N NH2 . ARG A 1 297 ? 4.465 10.648 -15.413 1.00 2.00 ? 297 ARG A NH2 1 ATOM 2347 N N . LYS A 1 298 ? 1.704 5.869 -20.591 1.00 2.00 ? 298 LYS A N 1 ATOM 2348 C CA . LYS A 1 298 ? 0.306 6.241 -20.515 1.00 2.00 ? 298 LYS A CA 1 ATOM 2349 C C . LYS A 1 298 ? -0.465 4.933 -20.475 1.00 2.15 ? 298 LYS A C 1 ATOM 2350 O O . LYS A 1 298 ? -1.301 4.715 -19.596 1.00 2.78 ? 298 LYS A O 1 ATOM 2351 C CB . LYS A 1 298 ? -0.108 7.087 -21.723 1.00 3.39 ? 298 LYS A CB 1 ATOM 2352 C CG . LYS A 1 298 ? -1.372 7.935 -21.476 1.00 3.49 ? 298 LYS A CG 1 ATOM 2353 C CD . LYS A 1 298 ? -1.290 9.294 -22.161 1.00 2.00 ? 298 LYS A CD 1 ATOM 2354 C CE . LYS A 1 298 ? -2.274 9.401 -23.289 1.00 2.00 ? 298 LYS A CE 1 ATOM 2355 N NZ . LYS A 1 298 ? -1.560 9.963 -24.456 1.00 4.52 ? 298 LYS A NZ 1 ATOM 2356 N N . ILE A 1 299 ? -0.153 4.056 -21.422 1.00 2.00 ? 299 ILE A N 1 ATOM 2357 C CA . ILE A 1 299 ? -0.794 2.749 -21.505 1.00 2.83 ? 299 ILE A CA 1 ATOM 2358 C C . ILE A 1 299 ? -0.728 2.038 -20.144 1.00 2.31 ? 299 ILE A C 1 ATOM 2359 O O . ILE A 1 299 ? -1.695 1.401 -19.713 1.00 2.00 ? 299 ILE A O 1 ATOM 2360 C CB . ILE A 1 299 ? -0.105 1.853 -22.612 1.00 2.16 ? 299 ILE A CB 1 ATOM 2361 C CG1 . ILE A 1 299 ? -0.601 2.253 -24.007 1.00 2.08 ? 299 ILE A CG1 1 ATOM 2362 C CG2 . ILE A 1 299 ? -0.393 0.373 -22.376 1.00 2.82 ? 299 ILE A CG2 1 ATOM 2363 C CD1 . ILE A 1 299 ? -0.005 1.423 -25.144 1.00 2.00 ? 299 ILE A CD1 1 ATOM 2364 N N . LEU A 1 300 ? 0.400 2.176 -19.455 1.00 2.00 ? 300 LEU A N 1 ATOM 2365 C CA . LEU A 1 300 ? 0.580 1.503 -18.182 1.00 2.00 ? 300 LEU A CA 1 ATOM 2366 C C . LEU A 1 300 ? -0.258 2.052 -17.031 1.00 2.89 ? 300 LEU A C 1 ATOM 2367 O O . LEU A 1 300 ? -0.911 1.284 -16.325 1.00 3.17 ? 300 LEU A O 1 ATOM 2368 C CB . LEU A 1 300 ? 2.066 1.486 -17.812 1.00 2.00 ? 300 LEU A CB 1 ATOM 2369 C CG . LEU A 1 300 ? 2.479 0.624 -16.611 1.00 2.00 ? 300 LEU A CG 1 ATOM 2370 C CD1 . LEU A 1 300 ? 1.876 -0.767 -16.706 1.00 2.00 ? 300 LEU A CD1 1 ATOM 2371 C CD2 . LEU A 1 300 ? 3.987 0.541 -16.554 1.00 2.00 ? 300 LEU A CD2 1 ATOM 2372 N N . GLY A 1 301 ? -0.247 3.366 -16.830 1.00 2.87 ? 301 GLY A N 1 ATOM 2373 C CA . GLY A 1 301 ? -1.039 3.931 -15.748 1.00 2.00 ? 301 GLY A CA 1 ATOM 2374 C C . GLY A 1 301 ? -2.477 3.494 -15.917 1.00 2.00 ? 301 GLY A C 1 ATOM 2375 O O . GLY A 1 301 ? -3.088 2.942 -15.007 1.00 2.00 ? 301 GLY A O 1 ATOM 2376 N N . ALA A 1 302 ? -3.007 3.735 -17.112 1.00 2.07 ? 302 ALA A N 1 ATOM 2377 C CA . ALA A 1 302 ? -4.377 3.360 -17.453 1.00 2.73 ? 302 ALA A CA 1 ATOM 2378 C C . ALA A 1 302 ? -4.641 1.916 -17.051 1.00 2.10 ? 302 ALA A C 1 ATOM 2379 O O . ALA A 1 302 ? -5.757 1.547 -16.684 1.00 2.00 ? 302 ALA A O 1 ATOM 2380 C CB . ALA A 1 302 ? -4.607 3.525 -18.951 1.00 2.00 ? 302 ALA A CB 1 ATOM 2381 N N . PHE A 1 303 ? -3.609 1.092 -17.137 1.00 2.00 ? 303 PHE A N 1 ATOM 2382 C CA . PHE A 1 303 ? -3.763 -0.292 -16.763 1.00 2.26 ? 303 PHE A CA 1 ATOM 2383 C C . PHE A 1 303 ? -4.017 -0.360 -15.258 1.00 3.81 ? 303 PHE A C 1 ATOM 2384 O O . PHE A 1 303 ? -4.999 -0.965 -14.822 1.00 4.97 ? 303 PHE A O 1 ATOM 2385 C CB . PHE A 1 303 ? -2.512 -1.088 -17.132 1.00 2.00 ? 303 PHE A CB 1 ATOM 2386 C CG . PHE A 1 303 ? -2.502 -2.476 -16.571 1.00 2.00 ? 303 PHE A CG 1 ATOM 2387 C CD1 . PHE A 1 303 ? -3.418 -3.423 -17.002 1.00 2.00 ? 303 PHE A CD1 1 ATOM 2388 C CD2 . PHE A 1 303 ? -1.607 -2.822 -15.571 1.00 2.00 ? 303 PHE A CD2 1 ATOM 2389 C CE1 . PHE A 1 303 ? -3.443 -4.697 -16.440 1.00 2.19 ? 303 PHE A CE1 1 ATOM 2390 C CE2 . PHE A 1 303 ? -1.627 -4.089 -15.006 1.00 2.00 ? 303 PHE A CE2 1 ATOM 2391 C CZ . PHE A 1 303 ? -2.547 -5.028 -15.441 1.00 2.00 ? 303 PHE A CZ 1 ATOM 2392 N N . ILE A 1 304 ? -3.148 0.271 -14.467 1.00 3.47 ? 304 ILE A N 1 ATOM 2393 C CA . ILE A 1 304 ? -3.303 0.255 -13.011 1.00 2.60 ? 304 ILE A CA 1 ATOM 2394 C C . ILE A 1 304 ? -4.726 0.680 -12.662 1.00 4.38 ? 304 ILE A C 1 ATOM 2395 O O . ILE A 1 304 ? -5.497 -0.093 -12.082 1.00 5.51 ? 304 ILE A O 1 ATOM 2396 C CB . ILE A 1 304 ? -2.346 1.238 -12.300 1.00 2.84 ? 304 ILE A CB 1 ATOM 2397 C CG1 . ILE A 1 304 ? -0.928 1.125 -12.865 1.00 2.36 ? 304 ILE A CG1 1 ATOM 2398 C CG2 . ILE A 1 304 ? -2.339 0.943 -10.808 1.00 2.00 ? 304 ILE A CG2 1 ATOM 2399 C CD1 . ILE A 1 304 ? -0.163 -0.081 -12.386 1.00 2.35 ? 304 ILE A CD1 1 ATOM 2400 N N . GLN A 1 305 ? -5.066 1.913 -13.023 1.00 3.57 ? 305 GLN A N 1 ATOM 2401 C CA . GLN A 1 305 ? -6.389 2.442 -12.755 1.00 2.00 ? 305 GLN A CA 1 ATOM 2402 C C . GLN A 1 305 ? -7.490 1.416 -12.975 1.00 2.00 ? 305 GLN A C 1 ATOM 2403 O O . GLN A 1 305 ? -8.317 1.187 -12.093 1.00 2.39 ? 305 GLN A O 1 ATOM 2404 C CB . GLN A 1 305 ? -6.635 3.679 -13.616 1.00 2.00 ? 305 GLN A CB 1 ATOM 2405 C CG . GLN A 1 305 ? -5.954 4.909 -13.048 1.00 3.88 ? 305 GLN A CG 1 ATOM 2406 C CD . GLN A 1 305 ? -6.139 6.154 -13.891 1.00 3.24 ? 305 GLN A CD 1 ATOM 2407 O OE1 . GLN A 1 305 ? -6.981 6.199 -14.786 1.00 3.40 ? 305 GLN A OE1 1 ATOM 2408 N NE2 . GLN A 1 305 ? -5.353 7.183 -13.594 1.00 2.56 ? 305 GLN A NE2 1 ATOM 2409 N N . ILE A 1 306 ? -7.495 0.769 -14.134 1.00 2.46 ? 306 ILE A N 1 ATOM 2410 C CA . ILE A 1 306 ? -8.544 -0.203 -14.403 1.00 3.35 ? 306 ILE A CA 1 ATOM 2411 C C . ILE A 1 306 ? -8.615 -1.335 -13.403 1.00 2.31 ? 306 ILE A C 1 ATOM 2412 O O . ILE A 1 306 ? -9.626 -1.506 -12.726 1.00 3.28 ? 306 ILE A O 1 ATOM 2413 C CB . ILE A 1 306 ? -8.419 -0.806 -15.792 1.00 2.00 ? 306 ILE A CB 1 ATOM 2414 C CG1 . ILE A 1 306 ? -8.636 0.284 -16.831 1.00 2.00 ? 306 ILE A CG1 1 ATOM 2415 C CG2 . ILE A 1 306 ? -9.460 -1.892 -15.970 1.00 2.00 ? 306 ILE A CG2 1 ATOM 2416 C CD1 . ILE A 1 306 ? -8.724 -0.230 -18.220 1.00 2.00 ? 306 ILE A CD1 1 ATOM 2417 N N . ILE A 1 307 ? -7.547 -2.111 -13.317 1.00 2.00 ? 307 ILE A N 1 ATOM 2418 C CA . ILE A 1 307 ? -7.508 -3.230 -12.396 1.00 2.00 ? 307 ILE A CA 1 ATOM 2419 C C . ILE A 1 307 ? -7.960 -2.802 -11.001 1.00 2.45 ? 307 ILE A C 1 ATOM 2420 O O . ILE A 1 307 ? -8.698 -3.525 -10.323 1.00 2.69 ? 307 ILE A O 1 ATOM 2421 C CB . ILE A 1 307 ? -6.093 -3.805 -12.343 1.00 2.00 ? 307 ILE A CB 1 ATOM 2422 C CG1 . ILE A 1 307 ? -5.638 -4.118 -13.768 1.00 2.30 ? 307 ILE A CG1 1 ATOM 2423 C CG2 . ILE A 1 307 ? -6.058 -5.064 -11.480 1.00 2.12 ? 307 ILE A CG2 1 ATOM 2424 C CD1 . ILE A 1 307 ? -6.578 -5.066 -14.511 1.00 2.00 ? 307 ILE A CD1 1 ATOM 2425 N N . THR A 1 308 ? -7.535 -1.610 -10.592 1.00 2.00 ? 308 THR A N 1 ATOM 2426 C CA . THR A 1 308 ? -7.883 -1.076 -9.283 1.00 2.56 ? 308 THR A CA 1 ATOM 2427 C C . THR A 1 308 ? -9.371 -0.733 -9.101 1.00 3.31 ? 308 THR A C 1 ATOM 2428 O O . THR A 1 308 ? -9.954 -1.040 -8.060 1.00 4.05 ? 308 THR A O 1 ATOM 2429 C CB . THR A 1 308 ? -7.022 0.168 -8.966 1.00 2.22 ? 308 THR A CB 1 ATOM 2430 O OG1 . THR A 1 308 ? -5.673 -0.244 -8.727 1.00 2.00 ? 308 THR A OG1 1 ATOM 2431 C CG2 . THR A 1 308 ? -7.546 0.901 -7.742 1.00 2.00 ? 308 THR A CG2 1 ATOM 2432 N N . PHE A 1 309 ? -10.000 -0.114 -10.094 1.00 2.57 ? 309 PHE A N 1 ATOM 2433 C CA . PHE A 1 309 ? -11.405 0.296 -9.900 1.00 2.00 ? 309 PHE A CA 1 ATOM 2434 C C . PHE A 1 309 ? -12.332 -0.758 -10.393 1.00 2.00 ? 309 PHE A C 1 ATOM 2435 O O . PHE A 1 309 ? -13.494 -0.869 -9.987 1.00 2.00 ? 309 PHE A O 1 ATOM 2436 C CB . PHE A 1 309 ? -11.686 1.617 -10.579 1.00 2.00 ? 309 PHE A CB 1 ATOM 2437 C CG . PHE A 1 309 ? -11.210 2.755 -9.765 1.00 2.12 ? 309 PHE A CG 1 ATOM 2438 C CD1 . PHE A 1 309 ? -9.864 3.103 -9.734 1.00 3.10 ? 309 PHE A CD1 1 ATOM 2439 C CD2 . PHE A 1 309 ? -12.108 3.498 -9.012 1.00 2.00 ? 309 PHE A CD2 1 ATOM 2440 C CE1 . PHE A 1 309 ? -9.420 4.174 -8.967 1.00 2.00 ? 309 PHE A CE1 1 ATOM 2441 C CE2 . PHE A 1 309 ? -11.680 4.563 -8.243 1.00 2.00 ? 309 PHE A CE2 1 ATOM 2442 C CZ . PHE A 1 309 ? -10.331 4.905 -8.220 1.00 2.78 ? 309 PHE A CZ 1 ATOM 2443 N N . ARG A 1 310 ? -11.800 -1.571 -11.272 1.00 2.93 ? 310 ARG A N 1 ATOM 2444 C CA . ARG A 1 310 ? -12.625 -2.586 -11.833 1.00 2.10 ? 310 ARG A CA 1 ATOM 2445 C C . ARG A 1 310 ? -12.526 -3.981 -11.198 1.00 2.50 ? 310 ARG A C 1 ATOM 2446 O O . ARG A 1 310 ? -13.562 -4.669 -11.213 1.00 2.05 ? 310 ARG A O 1 ATOM 2447 C CB . ARG A 1 310 ? -12.374 -2.739 -13.307 1.00 2.00 ? 310 ARG A CB 1 ATOM 2448 C CG . ARG A 1 310 ? -13.298 -3.826 -13.844 1.00 2.00 ? 310 ARG A CG 1 ATOM 2449 C CD . ARG A 1 310 ? -12.862 -4.345 -15.201 1.00 2.00 ? 310 ARG A CD 1 ATOM 2450 N NE . ARG A 1 310 ? -11.743 -5.278 -15.130 1.00 2.22 ? 310 ARG A NE 1 ATOM 2451 C CZ . ARG A 1 310 ? -11.038 -5.708 -16.177 1.00 2.00 ? 310 ARG A CZ 1 ATOM 2452 N NH1 . ARG A 1 310 ? -11.348 -5.294 -17.406 1.00 2.00 ? 310 ARG A NH1 1 ATOM 2453 N NH2 . ARG A 1 310 ? -10.040 -6.554 -15.985 1.00 2.00 ? 310 ARG A NH2 1 ATOM 2454 N N . ASP A 1 311 ? -11.443 -4.463 -10.677 1.00 2.49 ? 311 ASP A N 1 ATOM 2455 C CA . ASP A 1 311 ? -11.613 -5.839 -10.181 1.00 2.60 ? 311 ASP A CA 1 ATOM 2456 C C . ASP A 1 311 ? -11.330 -5.808 -8.712 1.00 2.00 ? 311 ASP A C 1 ATOM 2457 O O . ASP A 1 311 ? -11.677 -6.706 -7.953 1.00 2.00 ? 311 ASP A O 1 ATOM 2458 C CB . ASP A 1 311 ? -10.631 -6.795 -10.822 1.00 3.94 ? 311 ASP A CB 1 ATOM 2459 C CG . ASP A 1 311 ? -10.808 -6.792 -12.324 1.00 5.81 ? 311 ASP A CG 1 ATOM 2460 O OD1 . ASP A 1 311 ? -11.951 -7.005 -12.779 1.00 7.61 ? 311 ASP A OD1 1 ATOM 2461 O OD2 . ASP A 1 311 ? -9.809 -6.591 -13.045 1.00 5.36 ? 311 ASP A OD2 1 ATOM 2462 N N . TYR A 1 312 ? -10.668 -4.733 -8.368 1.00 2.00 ? 312 TYR A N 1 ATOM 2463 C CA . TYR A 1 312 ? -10.171 -4.611 -7.032 1.00 2.00 ? 312 TYR A CA 1 ATOM 2464 C C . TYR A 1 312 ? -10.958 -3.847 -6.023 1.00 2.00 ? 312 TYR A C 1 ATOM 2465 O O . TYR A 1 312 ? -11.118 -4.291 -4.897 1.00 2.00 ? 312 TYR A O 1 ATOM 2466 C CB . TYR A 1 312 ? -8.818 -3.977 -7.090 1.00 2.33 ? 312 TYR A CB 1 ATOM 2467 C CG . TYR A 1 312 ? -8.384 -3.674 -5.684 1.00 3.19 ? 312 TYR A CG 1 ATOM 2468 C CD1 . TYR A 1 312 ? -7.989 -4.699 -4.842 1.00 3.53 ? 312 TYR A CD1 1 ATOM 2469 C CD2 . TYR A 1 312 ? -8.365 -2.370 -5.211 1.00 3.43 ? 312 TYR A CD2 1 ATOM 2470 C CE1 . TYR A 1 312 ? -7.561 -4.405 -3.569 1.00 3.67 ? 312 TYR A CE1 1 ATOM 2471 C CE2 . TYR A 1 312 ? -7.937 -2.065 -3.934 1.00 4.27 ? 312 TYR A CE2 1 ATOM 2472 C CZ . TYR A 1 312 ? -7.521 -3.107 -3.120 1.00 3.98 ? 312 TYR A CZ 1 ATOM 2473 O OH . TYR A 1 312 ? -7.070 -2.826 -1.849 1.00 6.14 ? 312 TYR A OH 1 ATOM 2474 N N . LEU A 1 313 ? -11.456 -2.692 -6.418 1.00 2.53 ? 313 LEU A N 1 ATOM 2475 C CA . LEU A 1 313 ? -12.165 -1.951 -5.410 1.00 2.00 ? 313 LEU A CA 1 ATOM 2476 C C . LEU A 1 313 ? -13.515 -2.530 -5.153 1.00 2.00 ? 313 LEU A C 1 ATOM 2477 O O . LEU A 1 313 ? -14.007 -2.527 -4.024 1.00 2.00 ? 313 LEU A O 1 ATOM 2478 C CB . LEU A 1 313 ? -12.253 -0.480 -5.796 1.00 2.00 ? 313 LEU A CB 1 ATOM 2479 C CG . LEU A 1 313 ? -11.009 0.358 -5.469 1.00 2.00 ? 313 LEU A CG 1 ATOM 2480 C CD1 . LEU A 1 313 ? -11.124 1.765 -6.037 1.00 2.00 ? 313 LEU A CD1 1 ATOM 2481 C CD2 . LEU A 1 313 ? -10.801 0.416 -3.962 1.00 2.00 ? 313 LEU A CD2 1 ATOM 2482 N N . PRO A 1 314 ? -14.156 -3.042 -6.206 1.00 2.00 ? 314 PRO A N 1 ATOM 2483 C CA . PRO A 1 314 ? -15.498 -3.607 -6.072 1.00 2.00 ? 314 PRO A CA 1 ATOM 2484 C C . PRO A 1 314 ? -15.545 -4.719 -5.034 1.00 2.00 ? 314 PRO A C 1 ATOM 2485 O O . PRO A 1 314 ? -16.610 -5.031 -4.502 1.00 2.00 ? 314 PRO A O 1 ATOM 2486 C CB . PRO A 1 314 ? -15.794 -4.114 -7.469 1.00 2.00 ? 314 PRO A CB 1 ATOM 2487 C CG . PRO A 1 314 ? -15.125 -3.100 -8.314 1.00 2.00 ? 314 PRO A CG 1 ATOM 2488 C CD . PRO A 1 314 ? -13.799 -2.898 -7.626 1.00 2.21 ? 314 PRO A CD 1 ATOM 2489 N N . ILE A 1 315 ? -14.398 -5.329 -4.745 1.00 2.30 ? 315 ILE A N 1 ATOM 2490 C CA . ILE A 1 315 ? -14.382 -6.396 -3.744 1.00 3.03 ? 315 ILE A CA 1 ATOM 2491 C C . ILE A 1 315 ? -13.770 -6.025 -2.396 1.00 2.76 ? 315 ILE A C 1 ATOM 2492 O O . ILE A 1 315 ? -13.700 -6.860 -1.503 1.00 3.93 ? 315 ILE A O 1 ATOM 2493 C CB . ILE A 1 315 ? -13.704 -7.705 -4.260 1.00 2.70 ? 315 ILE A CB 1 ATOM 2494 C CG1 . ILE A 1 315 ? -12.222 -7.484 -4.582 1.00 2.79 ? 315 ILE A CG1 1 ATOM 2495 C CG2 . ILE A 1 315 ? -14.464 -8.220 -5.464 1.00 3.13 ? 315 ILE A CG2 1 ATOM 2496 C CD1 . ILE A 1 315 ? -11.530 -8.725 -5.159 1.00 2.00 ? 315 ILE A CD1 1 ATOM 2497 N N . VAL A 1 316 ? -13.313 -4.789 -2.244 1.00 2.00 ? 316 VAL A N 1 ATOM 2498 C CA . VAL A 1 316 ? -12.788 -4.369 -0.954 1.00 2.00 ? 316 VAL A CA 1 ATOM 2499 C C . VAL A 1 316 ? -13.977 -3.737 -0.249 1.00 3.29 ? 316 VAL A C 1 ATOM 2500 O O . VAL A 1 316 ? -14.244 -4.014 0.924 1.00 2.98 ? 316 VAL A O 1 ATOM 2501 C CB . VAL A 1 316 ? -11.703 -3.293 -1.066 1.00 2.00 ? 316 VAL A CB 1 ATOM 2502 C CG1 . VAL A 1 316 ? -11.346 -2.776 0.323 1.00 2.00 ? 316 VAL A CG1 1 ATOM 2503 C CG2 . VAL A 1 316 ? -10.490 -3.856 -1.755 1.00 2.89 ? 316 VAL A CG2 1 ATOM 2504 N N . LEU A 1 317 ? -14.693 -2.891 -0.992 1.00 2.12 ? 317 LEU A N 1 ATOM 2505 C CA . LEU A 1 317 ? -15.854 -2.177 -0.474 1.00 2.00 ? 317 LEU A CA 1 ATOM 2506 C C . LEU A 1 317 ? -17.142 -2.994 -0.445 1.00 3.48 ? 317 LEU A C 1 ATOM 2507 O O . LEU A 1 317 ? -17.958 -2.846 0.468 1.00 2.85 ? 317 LEU A O 1 ATOM 2508 C CB . LEU A 1 317 ? -16.083 -0.907 -1.288 1.00 2.00 ? 317 LEU A CB 1 ATOM 2509 C CG . LEU A 1 317 ? -15.328 0.363 -0.907 1.00 2.00 ? 317 LEU A CG 1 ATOM 2510 C CD1 . LEU A 1 317 ? -14.343 0.083 0.203 1.00 2.69 ? 317 LEU A CD1 1 ATOM 2511 C CD2 . LEU A 1 317 ? -14.624 0.915 -2.134 1.00 2.00 ? 317 LEU A CD2 1 ATOM 2512 N N . GLY A 1 318 ? -17.328 -3.850 -1.444 1.00 2.93 ? 318 GLY A N 1 ATOM 2513 C CA . GLY A 1 318 ? -18.536 -4.653 -1.493 1.00 2.24 ? 318 GLY A CA 1 ATOM 2514 C C . GLY A 1 318 ? -19.788 -3.824 -1.708 1.00 3.21 ? 318 GLY A C 1 ATOM 2515 O O . GLY A 1 318 ? -19.847 -2.964 -2.582 1.00 3.91 ? 318 GLY A O 1 ATOM 2516 N N . SER A 1 319 ? -20.801 -4.064 -0.898 1.00 3.22 ? 319 SER A N 1 ATOM 2517 C CA . SER A 1 319 ? -22.049 -3.347 -1.051 1.00 5.50 ? 319 SER A CA 1 ATOM 2518 C C . SER A 1 319 ? -22.017 -1.865 -0.676 1.00 6.53 ? 319 SER A C 1 ATOM 2519 O O . SER A 1 319 ? -23.071 -1.245 -0.548 1.00 7.92 ? 319 SER A O 1 ATOM 2520 C CB . SER A 1 319 ? -23.130 -4.065 -0.246 1.00 7.47 ? 319 SER A CB 1 ATOM 2521 O OG . SER A 1 319 ? -22.652 -4.390 1.053 1.00 10.31 ? 319 SER A OG 1 ATOM 2522 N N . GLU A 1 320 ? -20.829 -1.291 -0.504 1.00 5.62 ? 320 GLU A N 1 ATOM 2523 C CA . GLU A 1 320 ? -20.725 0.126 -0.144 1.00 6.53 ? 320 GLU A CA 1 ATOM 2524 C C . GLU A 1 320 ? -20.028 0.935 -1.238 1.00 7.30 ? 320 GLU A C 1 ATOM 2525 O O . GLU A 1 320 ? -19.677 2.104 -1.048 1.00 6.40 ? 320 GLU A O 1 ATOM 2526 C CB . GLU A 1 320 ? -19.949 0.287 1.162 1.00 7.38 ? 320 GLU A CB 1 ATOM 2527 C CG . GLU A 1 320 ? -20.554 -0.419 2.352 1.00 7.62 ? 320 GLU A CG 1 ATOM 2528 C CD . GLU A 1 320 ? -21.593 0.413 3.061 1.00 8.11 ? 320 GLU A CD 1 ATOM 2529 O OE1 . GLU A 1 320 ? -21.302 1.596 3.340 1.00 8.88 ? 320 GLU A OE1 1 ATOM 2530 O OE2 . GLU A 1 320 ? -22.689 -0.119 3.348 1.00 8.37 ? 320 GLU A OE2 1 ATOM 2531 N N . MET A 1 321 ? -19.829 0.298 -2.383 1.00 8.56 ? 321 MET A N 1 ATOM 2532 C CA . MET A 1 321 ? -19.170 0.936 -3.513 1.00 10.54 ? 321 MET A CA 1 ATOM 2533 C C . MET A 1 321 ? -20.084 1.896 -4.273 1.00 13.52 ? 321 MET A C 1 ATOM 2534 O O . MET A 1 321 ? -19.664 2.986 -4.654 1.00 13.89 ? 321 MET A O 1 ATOM 2535 C CB . MET A 1 321 ? -18.636 -0.132 -4.462 1.00 8.01 ? 321 MET A CB 1 ATOM 2536 C CG . MET A 1 321 ? -18.100 0.412 -5.750 1.00 6.17 ? 321 MET A CG 1 ATOM 2537 S SD . MET A 1 321 ? -16.506 -0.300 -6.115 1.00 6.27 ? 321 MET A SD 1 ATOM 2538 C CE . MET A 1 321 ? -15.649 1.129 -6.754 1.00 5.76 ? 321 MET A CE 1 ATOM 2539 N N . GLN A 1 322 ? -21.330 1.499 -4.503 1.00 16.51 ? 322 GLN A N 1 ATOM 2540 C CA . GLN A 1 322 ? -22.255 2.375 -5.210 1.00 18.36 ? 322 GLN A CA 1 ATOM 2541 C C . GLN A 1 322 ? -22.531 3.615 -4.356 1.00 17.29 ? 322 GLN A C 1 ATOM 2542 O O . GLN A 1 322 ? -22.636 4.731 -4.867 1.00 16.07 ? 322 GLN A O 1 ATOM 2543 C CB . GLN A 1 322 ? -23.557 1.631 -5.504 1.00 23.15 ? 322 GLN A CB 1 ATOM 2544 C CG . GLN A 1 322 ? -23.382 0.416 -6.405 1.00 29.19 ? 322 GLN A CG 1 ATOM 2545 C CD . GLN A 1 322 ? -24.678 -0.356 -6.589 1.00 32.29 ? 322 GLN A CD 1 ATOM 2546 O OE1 . GLN A 1 322 ? -25.282 -0.818 -5.616 1.00 34.43 ? 322 GLN A OE1 1 ATOM 2547 N NE2 . GLN A 1 322 ? -25.112 -0.499 -7.838 1.00 33.81 ? 322 GLN A NE2 1 ATOM 2548 N N . LYS A 1 323 ? -22.625 3.392 -3.048 1.00 15.60 ? 323 LYS A N 1 ATOM 2549 C CA . LYS A 1 323 ? -22.884 4.428 -2.053 1.00 14.03 ? 323 LYS A CA 1 ATOM 2550 C C . LYS A 1 323 ? -21.832 5.552 -2.034 1.00 14.34 ? 323 LYS A C 1 ATOM 2551 O O . LYS A 1 323 ? -22.164 6.715 -1.784 1.00 15.12 ? 323 LYS A O 1 ATOM 2552 C CB . LYS A 1 323 ? -22.961 3.763 -0.674 1.00 14.07 ? 323 LYS A CB 1 ATOM 2553 C CG . LYS A 1 323 ? -23.303 4.676 0.492 1.00 16.44 ? 323 LYS A CG 1 ATOM 2554 C CD . LYS A 1 323 ? -23.287 3.890 1.809 1.00 17.57 ? 323 LYS A CD 1 ATOM 2555 C CE . LYS A 1 323 ? -23.956 4.654 2.958 1.00 19.18 ? 323 LYS A CE 1 ATOM 2556 N NZ . LYS A 1 323 ? -23.279 5.948 3.297 1.00 19.77 ? 323 LYS A NZ 1 ATOM 2557 N N . TRP A 1 324 ? -20.573 5.204 -2.300 1.00 12.72 ? 324 TRP A N 1 ATOM 2558 C CA . TRP A 1 324 ? -19.479 6.176 -2.289 1.00 9.80 ? 324 TRP A CA 1 ATOM 2559 C C . TRP A 1 324 ? -18.882 6.489 -3.657 1.00 9.79 ? 324 TRP A C 1 ATOM 2560 O O . TRP A 1 324 ? -18.544 7.634 -3.965 1.00 9.16 ? 324 TRP A O 1 ATOM 2561 C CB . TRP A 1 324 ? -18.361 5.669 -1.389 1.00 9.95 ? 324 TRP A CB 1 ATOM 2562 C CG . TRP A 1 324 ? -18.775 5.524 0.008 1.00 11.37 ? 324 TRP A CG 1 ATOM 2563 C CD1 . TRP A 1 324 ? -18.833 4.370 0.732 1.00 12.31 ? 324 TRP A CD1 1 ATOM 2564 C CD2 . TRP A 1 324 ? -19.210 6.572 0.879 1.00 12.07 ? 324 TRP A CD2 1 ATOM 2565 N NE1 . TRP A 1 324 ? -19.280 4.633 2.009 1.00 13.39 ? 324 TRP A NE1 1 ATOM 2566 C CE2 . TRP A 1 324 ? -19.519 5.979 2.124 1.00 12.52 ? 324 TRP A CE2 1 ATOM 2567 C CE3 . TRP A 1 324 ? -19.369 7.957 0.729 1.00 11.41 ? 324 TRP A CE3 1 ATOM 2568 C CZ2 . TRP A 1 324 ? -19.981 6.726 3.214 1.00 11.59 ? 324 TRP A CZ2 1 ATOM 2569 C CZ3 . TRP A 1 324 ? -19.827 8.697 1.814 1.00 10.32 ? 324 TRP A CZ3 1 ATOM 2570 C CH2 . TRP A 1 324 ? -20.127 8.079 3.038 1.00 10.51 ? 324 TRP A CH2 1 ATOM 2571 N N . ILE A 1 325 ? -18.732 5.456 -4.468 1.00 8.63 ? 325 ILE A N 1 ATOM 2572 C CA . ILE A 1 325 ? -18.151 5.613 -5.786 1.00 7.66 ? 325 ILE A CA 1 ATOM 2573 C C . ILE A 1 325 ? -19.222 5.425 -6.864 1.00 8.85 ? 325 ILE A C 1 ATOM 2574 O O . ILE A 1 325 ? -19.444 4.316 -7.359 1.00 11.14 ? 325 ILE A O 1 ATOM 2575 C CB . ILE A 1 325 ? -16.974 4.603 -5.978 1.00 5.46 ? 325 ILE A CB 1 ATOM 2576 C CG1 . ILE A 1 325 ? -15.829 4.952 -5.019 1.00 3.99 ? 325 ILE A CG1 1 ATOM 2577 C CG2 . ILE A 1 325 ? -16.481 4.618 -7.406 1.00 4.60 ? 325 ILE A CG2 1 ATOM 2578 C CD1 . ILE A 1 325 ? -14.694 3.949 -5.012 1.00 2.70 ? 325 ILE A CD1 1 ATOM 2579 N N . PRO A 1 326 ? -19.925 6.513 -7.215 1.00 8.03 ? 326 PRO A N 1 ATOM 2580 C CA . PRO A 1 326 ? -20.968 6.468 -8.241 1.00 6.92 ? 326 PRO A CA 1 ATOM 2581 C C . PRO A 1 326 ? -20.249 6.296 -9.581 1.00 6.55 ? 326 PRO A C 1 ATOM 2582 O O . PRO A 1 326 ? -19.026 6.299 -9.622 1.00 5.42 ? 326 PRO A O 1 ATOM 2583 C CB . PRO A 1 326 ? -21.627 7.841 -8.120 1.00 7.72 ? 326 PRO A CB 1 ATOM 2584 C CG . PRO A 1 326 ? -21.284 8.296 -6.715 1.00 7.07 ? 326 PRO A CG 1 ATOM 2585 C CD . PRO A 1 326 ? -19.873 7.841 -6.581 1.00 7.16 ? 326 PRO A CD 1 ATOM 2586 N N . ARG A 1 327 ? -20.998 6.173 -10.670 1.00 7.82 ? 327 ARG A N 1 ATOM 2587 C CA . ARG A 1 327 ? -20.405 5.997 -11.997 1.00 11.26 ? 327 ARG A CA 1 ATOM 2588 C C . ARG A 1 327 ? -19.780 7.319 -12.501 1.00 10.67 ? 327 ARG A C 1 ATOM 2589 O O . ARG A 1 327 ? -20.364 8.390 -12.324 1.00 11.89 ? 327 ARG A O 1 ATOM 2590 C CB . ARG A 1 327 ? -21.491 5.474 -12.959 1.00 15.61 ? 327 ARG A CB 1 ATOM 2591 C CG . ARG A 1 327 ? -22.177 4.118 -12.514 1.00 23.88 ? 327 ARG A CG 1 ATOM 2592 C CD . ARG A 1 327 ? -23.097 4.250 -11.253 1.00 28.70 ? 327 ARG A CD 1 ATOM 2593 N NE . ARG A 1 327 ? -23.516 2.986 -10.604 1.00 33.02 ? 327 ARG A NE 1 ATOM 2594 C CZ . ARG A 1 327 ? -24.396 2.104 -11.089 1.00 34.29 ? 327 ARG A CZ 1 ATOM 2595 N NH1 . ARG A 1 327 ? -24.986 2.303 -12.261 1.00 35.26 ? 327 ARG A NH1 1 ATOM 2596 N NH2 . ARG A 1 327 ? -24.709 1.025 -10.380 1.00 36.12 ? 327 ARG A NH2 1 ATOM 2597 N N . TYR A 1 328 ? -18.595 7.257 -13.111 1.00 10.08 ? 328 TYR A N 1 ATOM 2598 C CA . TYR A 1 328 ? -17.911 8.467 -13.592 1.00 9.31 ? 328 TYR A CA 1 ATOM 2599 C C . TYR A 1 328 ? -18.765 9.299 -14.547 1.00 10.34 ? 328 TYR A C 1 ATOM 2600 O O . TYR A 1 328 ? -19.302 8.794 -15.548 1.00 9.12 ? 328 TYR A O 1 ATOM 2601 C CB . TYR A 1 328 ? -16.586 8.084 -14.269 1.00 8.37 ? 328 TYR A CB 1 ATOM 2602 C CG . TYR A 1 328 ? -15.668 9.213 -14.691 1.00 6.15 ? 328 TYR A CG 1 ATOM 2603 C CD1 . TYR A 1 328 ? -15.025 10.015 -13.751 1.00 6.72 ? 328 TYR A CD1 1 ATOM 2604 C CD2 . TYR A 1 328 ? -15.339 9.382 -16.031 1.00 6.14 ? 328 TYR A CD2 1 ATOM 2605 C CE1 . TYR A 1 328 ? -14.060 10.948 -14.142 1.00 6.82 ? 328 TYR A CE1 1 ATOM 2606 C CE2 . TYR A 1 328 ? -14.384 10.297 -16.431 1.00 5.86 ? 328 TYR A CE2 1 ATOM 2607 C CZ . TYR A 1 328 ? -13.743 11.072 -15.487 1.00 6.34 ? 328 TYR A CZ 1 ATOM 2608 O OH . TYR A 1 328 ? -12.744 11.921 -15.890 1.00 5.15 ? 328 TYR A OH 1 ATOM 2609 N N . GLN A 1 329 ? -18.901 10.578 -14.210 1.00 8.59 ? 329 GLN A N 1 ATOM 2610 C CA . GLN A 1 329 ? -19.667 11.506 -15.020 1.00 7.52 ? 329 GLN A CA 1 ATOM 2611 C C . GLN A 1 329 ? -18.700 12.552 -15.588 1.00 5.74 ? 329 GLN A C 1 ATOM 2612 O O . GLN A 1 329 ? -19.112 13.653 -15.944 1.00 6.61 ? 329 GLN A O 1 ATOM 2613 C CB . GLN A 1 329 ? -20.773 12.175 -14.185 1.00 11.72 ? 329 GLN A CB 1 ATOM 2614 C CG . GLN A 1 329 ? -21.892 11.244 -13.669 1.00 17.35 ? 329 GLN A CG 1 ATOM 2615 C CD . GLN A 1 329 ? -23.119 11.154 -14.592 1.00 20.30 ? 329 GLN A CD 1 ATOM 2616 O OE1 . GLN A 1 329 ? -23.121 10.474 -15.626 1.00 22.32 ? 329 GLN A OE1 1 ATOM 2617 N NE2 . GLN A 1 329 ? -24.180 11.856 -14.212 1.00 21.96 ? 329 GLN A NE2 1 ATOM 2618 N N . GLY A 1 330 ? -17.412 12.207 -15.656 1.00 2.65 ? 330 GLY A N 1 ATOM 2619 C CA . GLY A 1 330 ? -16.415 13.112 -16.216 1.00 2.00 ? 330 GLY A CA 1 ATOM 2620 C C . GLY A 1 330 ? -15.628 13.968 -15.239 1.00 2.00 ? 330 GLY A C 1 ATOM 2621 O O . GLY A 1 330 ? -16.002 14.097 -14.078 1.00 2.01 ? 330 GLY A O 1 ATOM 2622 N N . TYR A 1 331 ? -14.546 14.578 -15.711 1.00 2.14 ? 331 TYR A N 1 ATOM 2623 C CA . TYR A 1 331 ? -13.704 15.416 -14.859 1.00 2.37 ? 331 TYR A CA 1 ATOM 2624 C C . TYR A 1 331 ? -14.406 16.565 -14.123 1.00 3.34 ? 331 TYR A C 1 ATOM 2625 O O . TYR A 1 331 ? -14.954 17.481 -14.746 1.00 2.45 ? 331 TYR A O 1 ATOM 2626 C CB . TYR A 1 331 ? -12.542 15.967 -15.694 1.00 3.82 ? 331 TYR A CB 1 ATOM 2627 C CG . TYR A 1 331 ? -11.566 16.877 -14.970 1.00 5.77 ? 331 TYR A CG 1 ATOM 2628 C CD1 . TYR A 1 331 ? -11.113 16.588 -13.686 1.00 6.75 ? 331 TYR A CD1 1 ATOM 2629 C CD2 . TYR A 1 331 ? -11.024 17.990 -15.615 1.00 7.54 ? 331 TYR A CD2 1 ATOM 2630 C CE1 . TYR A 1 331 ? -10.137 17.387 -13.071 1.00 7.78 ? 331 TYR A CE1 1 ATOM 2631 C CE2 . TYR A 1 331 ? -10.051 18.785 -15.008 1.00 6.63 ? 331 TYR A CE2 1 ATOM 2632 C CZ . TYR A 1 331 ? -9.611 18.479 -13.749 1.00 6.09 ? 331 TYR A CZ 1 ATOM 2633 O OH . TYR A 1 331 ? -8.617 19.246 -13.199 1.00 6.81 ? 331 TYR A OH 1 ATOM 2634 N N . ASN A 1 332 ? -14.384 16.499 -12.792 1.00 4.38 ? 332 ASN A N 1 ATOM 2635 C CA . ASN A 1 332 ? -14.966 17.523 -11.921 1.00 7.42 ? 332 ASN A CA 1 ATOM 2636 C C . ASN A 1 332 ? -13.747 18.303 -11.403 1.00 6.74 ? 332 ASN A C 1 ATOM 2637 O O . ASN A 1 332 ? -13.223 17.992 -10.341 1.00 6.83 ? 332 ASN A O 1 ATOM 2638 C CB . ASN A 1 332 ? -15.712 16.865 -10.744 1.00 12.11 ? 332 ASN A CB 1 ATOM 2639 C CG . ASN A 1 332 ? -16.453 17.875 -9.873 1.00 19.49 ? 332 ASN A CG 1 ATOM 2640 O OD1 . ASN A 1 332 ? -15.956 18.960 -9.610 1.00 16.70 ? 332 ASN A OD1 1 ATOM 2641 N ND2 . ASN A 1 332 ? -17.649 17.518 -9.419 1.00 30.80 ? 332 ASN A ND2 1 ATOM 2642 N N . ASN A 1 333 ? -13.292 19.306 -12.154 1.00 6.36 ? 333 ASN A N 1 ATOM 2643 C CA . ASN A 1 333 ? -12.105 20.081 -11.769 1.00 6.66 ? 333 ASN A CA 1 ATOM 2644 C C . ASN A 1 333 ? -12.190 20.751 -10.406 1.00 6.43 ? 333 ASN A C 1 ATOM 2645 O O . ASN A 1 333 ? -11.178 21.197 -9.860 1.00 6.40 ? 333 ASN A O 1 ATOM 2646 C CB . ASN A 1 333 ? -11.785 21.151 -12.823 1.00 7.26 ? 333 ASN A CB 1 ATOM 2647 C CG . ASN A 1 333 ? -12.611 22.421 -12.647 1.00 7.05 ? 333 ASN A CG 1 ATOM 2648 O OD1 . ASN A 1 333 ? -12.371 23.214 -11.733 1.00 6.39 ? 333 ASN A OD1 1 ATOM 2649 N ND2 . ASN A 1 333 ? -13.590 22.616 -13.525 1.00 7.48 ? 333 ASN A ND2 1 ATOM 2650 N N . SER A 1 334 ? -13.387 20.840 -9.853 1.00 5.25 ? 334 SER A N 1 ATOM 2651 C CA . SER A 1 334 ? -13.518 21.462 -8.551 1.00 6.54 ? 334 SER A CA 1 ATOM 2652 C C . SER A 1 334 ? -13.327 20.467 -7.409 1.00 5.31 ? 334 SER A C 1 ATOM 2653 O O . SER A 1 334 ? -13.783 20.713 -6.297 1.00 7.63 ? 334 SER A O 1 ATOM 2654 C CB . SER A 1 334 ? -14.886 22.148 -8.417 1.00 7.62 ? 334 SER A CB 1 ATOM 2655 O OG . SER A 1 334 ? -14.882 23.442 -9.006 1.00 8.52 ? 334 SER A OG 1 ATOM 2656 N N . VAL A 1 335 ? -12.636 19.361 -7.664 1.00 3.93 ? 335 VAL A N 1 ATOM 2657 C CA . VAL A 1 335 ? -12.430 18.347 -6.627 1.00 2.06 ? 335 VAL A CA 1 ATOM 2658 C C . VAL A 1 335 ? -10.972 18.145 -6.165 1.00 2.00 ? 335 VAL A C 1 ATOM 2659 O O . VAL A 1 335 ? -10.091 17.848 -6.967 1.00 2.00 ? 335 VAL A O 1 ATOM 2660 C CB . VAL A 1 335 ? -13.001 16.993 -7.101 1.00 2.00 ? 335 VAL A CB 1 ATOM 2661 C CG1 . VAL A 1 335 ? -12.963 15.984 -5.981 1.00 2.00 ? 335 VAL A CG1 1 ATOM 2662 C CG2 . VAL A 1 335 ? -14.422 17.180 -7.590 1.00 2.00 ? 335 VAL A CG2 1 ATOM 2663 N N . ASP A 1 336 ? -10.731 18.297 -4.864 1.00 2.00 ? 336 ASP A N 1 ATOM 2664 C CA . ASP A 1 336 ? -9.393 18.125 -4.277 1.00 2.74 ? 336 ASP A CA 1 ATOM 2665 C C . ASP A 1 336 ? -8.898 16.672 -4.468 1.00 2.53 ? 336 ASP A C 1 ATOM 2666 O O . ASP A 1 336 ? -9.378 15.748 -3.806 1.00 2.14 ? 336 ASP A O 1 ATOM 2667 C CB . ASP A 1 336 ? -9.450 18.492 -2.778 1.00 3.25 ? 336 ASP A CB 1 ATOM 2668 C CG . ASP A 1 336 ? -8.069 18.568 -2.126 1.00 4.04 ? 336 ASP A CG 1 ATOM 2669 O OD1 . ASP A 1 336 ? -7.397 17.522 -2.027 1.00 6.00 ? 336 ASP A OD1 1 ATOM 2670 O OD2 . ASP A 1 336 ? -7.652 19.670 -1.707 1.00 4.10 ? 336 ASP A OD2 1 ATOM 2671 N N . PRO A 1 337 ? -7.916 16.456 -5.364 1.00 2.00 ? 337 PRO A N 1 ATOM 2672 C CA . PRO A 1 337 ? -7.370 15.123 -5.643 1.00 2.00 ? 337 PRO A CA 1 ATOM 2673 C C . PRO A 1 337 ? -6.298 14.624 -4.678 1.00 3.32 ? 337 PRO A C 1 ATOM 2674 O O . PRO A 1 337 ? -5.802 13.505 -4.833 1.00 3.14 ? 337 PRO A O 1 ATOM 2675 C CB . PRO A 1 337 ? -6.801 15.291 -7.036 1.00 2.00 ? 337 PRO A CB 1 ATOM 2676 C CG . PRO A 1 337 ? -6.145 16.614 -6.892 1.00 2.00 ? 337 PRO A CG 1 ATOM 2677 C CD . PRO A 1 337 ? -7.238 17.455 -6.207 1.00 2.00 ? 337 PRO A CD 1 ATOM 2678 N N . ARG A 1 338 ? -5.933 15.448 -3.699 1.00 3.03 ? 338 ARG A N 1 ATOM 2679 C CA . ARG A 1 338 ? -4.902 15.089 -2.723 1.00 2.00 ? 338 ARG A CA 1 ATOM 2680 C C . ARG A 1 338 ? -5.284 13.996 -1.756 1.00 2.00 ? 338 ARG A C 1 ATOM 2681 O O . ARG A 1 338 ? -6.453 13.837 -1.416 1.00 2.00 ? 338 ARG A O 1 ATOM 2682 C CB . ARG A 1 338 ? -4.521 16.294 -1.896 1.00 2.00 ? 338 ARG A CB 1 ATOM 2683 C CG . ARG A 1 338 ? -3.798 17.365 -2.649 1.00 2.67 ? 338 ARG A CG 1 ATOM 2684 C CD . ARG A 1 338 ? -3.579 18.506 -1.701 1.00 2.41 ? 338 ARG A CD 1 ATOM 2685 N NE . ARG A 1 338 ? -4.837 18.858 -1.062 1.00 2.00 ? 338 ARG A NE 1 ATOM 2686 C CZ . ARG A 1 338 ? -4.943 19.788 -0.132 1.00 2.00 ? 338 ARG A CZ 1 ATOM 2687 N NH1 . ARG A 1 338 ? -3.855 20.440 0.252 1.00 2.91 ? 338 ARG A NH1 1 ATOM 2688 N NH2 . ARG A 1 338 ? -6.123 20.068 0.405 1.00 2.04 ? 338 ARG A NH2 1 ATOM 2689 N N . ILE A 1 339 ? -4.281 13.264 -1.287 1.00 2.00 ? 339 ILE A N 1 ATOM 2690 C CA . ILE A 1 339 ? -4.520 12.193 -0.330 1.00 3.75 ? 339 ILE A CA 1 ATOM 2691 C C . ILE A 1 339 ? -4.642 12.794 1.071 1.00 2.53 ? 339 ILE A C 1 ATOM 2692 O O . ILE A 1 339 ? -3.801 13.589 1.485 1.00 3.61 ? 339 ILE A O 1 ATOM 2693 C CB . ILE A 1 339 ? -3.372 11.158 -0.334 1.00 2.20 ? 339 ILE A CB 1 ATOM 2694 C CG1 . ILE A 1 339 ? -3.207 10.549 -1.732 1.00 2.24 ? 339 ILE A CG1 1 ATOM 2695 C CG2 . ILE A 1 339 ? -3.675 10.057 0.665 1.00 2.07 ? 339 ILE A CG2 1 ATOM 2696 C CD1 . ILE A 1 339 ? -4.462 9.870 -2.279 1.00 2.00 ? 339 ILE A CD1 1 ATOM 2697 N N . SER A 1 340 ? -5.700 12.427 1.788 1.00 2.00 ? 340 SER A N 1 ATOM 2698 C CA . SER A 1 340 ? -5.921 12.935 3.135 1.00 2.00 ? 340 SER A CA 1 ATOM 2699 C C . SER A 1 340 ? -4.972 12.198 4.033 1.00 2.00 ? 340 SER A C 1 ATOM 2700 O O . SER A 1 340 ? -4.396 11.191 3.628 1.00 2.41 ? 340 SER A O 1 ATOM 2701 C CB . SER A 1 340 ? -7.342 12.658 3.598 1.00 2.00 ? 340 SER A CB 1 ATOM 2702 O OG . SER A 1 340 ? -7.533 11.275 3.826 1.00 2.00 ? 340 SER A OG 1 ATOM 2703 N N . ASN A 1 341 ? -4.818 12.676 5.259 1.00 2.00 ? 341 ASN A N 1 ATOM 2704 C CA . ASN A 1 341 ? -3.899 12.027 6.168 1.00 2.00 ? 341 ASN A CA 1 ATOM 2705 C C . ASN A 1 341 ? -4.470 10.703 6.595 1.00 2.00 ? 341 ASN A C 1 ATOM 2706 O O . ASN A 1 341 ? -3.820 9.667 6.474 1.00 2.57 ? 341 ASN A O 1 ATOM 2707 C CB . ASN A 1 341 ? -3.654 12.882 7.399 1.00 2.00 ? 341 ASN A CB 1 ATOM 2708 C CG . ASN A 1 341 ? -2.354 12.540 8.081 1.00 2.00 ? 341 ASN A CG 1 ATOM 2709 O OD1 . ASN A 1 341 ? -2.073 11.376 8.356 1.00 2.01 ? 341 ASN A OD1 1 ATOM 2710 N ND2 . ASN A 1 341 ? -1.548 13.555 8.359 1.00 2.00 ? 341 ASN A ND2 1 ATOM 2711 N N . VAL A 1 342 ? -5.703 10.740 7.080 1.00 2.50 ? 342 VAL A N 1 ATOM 2712 C CA . VAL A 1 342 ? -6.364 9.536 7.553 1.00 2.00 ? 342 VAL A CA 1 ATOM 2713 C C . VAL A 1 342 ? -6.355 8.392 6.544 1.00 2.12 ? 342 VAL A C 1 ATOM 2714 O O . VAL A 1 342 ? -6.314 7.231 6.937 1.00 3.32 ? 342 VAL A O 1 ATOM 2715 C CB . VAL A 1 342 ? -7.804 9.819 7.935 1.00 2.00 ? 342 VAL A CB 1 ATOM 2716 C CG1 . VAL A 1 342 ? -8.628 9.995 6.681 1.00 3.87 ? 342 VAL A CG1 1 ATOM 2717 C CG2 . VAL A 1 342 ? -8.338 8.699 8.797 1.00 2.00 ? 342 VAL A CG2 1 ATOM 2718 N N . PHE A 1 343 ? -6.397 8.703 5.252 1.00 2.00 ? 343 PHE A N 1 ATOM 2719 C CA . PHE A 1 343 ? -6.387 7.644 4.251 1.00 2.00 ? 343 PHE A CA 1 ATOM 2720 C C . PHE A 1 343 ? -5.187 6.755 4.492 1.00 2.00 ? 343 PHE A C 1 ATOM 2721 O O . PHE A 1 343 ? -5.280 5.528 4.385 1.00 2.00 ? 343 PHE A O 1 ATOM 2722 C CB . PHE A 1 343 ? -6.293 8.211 2.838 1.00 2.00 ? 343 PHE A CB 1 ATOM 2723 C CG . PHE A 1 343 ? -6.418 7.170 1.759 1.00 2.00 ? 343 PHE A CG 1 ATOM 2724 C CD1 . PHE A 1 343 ? -7.570 6.402 1.651 1.00 2.00 ? 343 PHE A CD1 1 ATOM 2725 C CD2 . PHE A 1 343 ? -5.389 6.959 0.850 1.00 2.00 ? 343 PHE A CD2 1 ATOM 2726 C CE1 . PHE A 1 343 ? -7.696 5.438 0.650 1.00 2.00 ? 343 PHE A CE1 1 ATOM 2727 C CE2 . PHE A 1 343 ? -5.507 5.995 -0.155 1.00 2.00 ? 343 PHE A CE2 1 ATOM 2728 C CZ . PHE A 1 343 ? -6.664 5.235 -0.254 1.00 2.00 ? 343 PHE A CZ 1 ATOM 2729 N N . THR A 1 344 ? -4.066 7.383 4.841 1.00 2.00 ? 344 THR A N 1 ATOM 2730 C CA . THR A 1 344 ? -2.830 6.646 5.070 1.00 2.12 ? 344 THR A CA 1 ATOM 2731 C C . THR A 1 344 ? -2.859 5.747 6.305 1.00 2.00 ? 344 THR A C 1 ATOM 2732 O O . THR A 1 344 ? -1.887 5.065 6.609 1.00 2.00 ? 344 THR A O 1 ATOM 2733 C CB . THR A 1 344 ? -1.585 7.589 5.132 1.00 2.10 ? 344 THR A CB 1 ATOM 2734 O OG1 . THR A 1 344 ? -1.387 8.044 6.470 1.00 4.20 ? 344 THR A OG1 1 ATOM 2735 C CG2 . THR A 1 344 ? -1.765 8.794 4.218 1.00 2.00 ? 344 THR A CG2 1 ATOM 2736 N N . PHE A 1 345 ? -3.972 5.741 7.023 1.00 2.01 ? 345 PHE A N 1 ATOM 2737 C CA . PHE A 1 345 ? -4.089 4.862 8.182 1.00 3.04 ? 345 PHE A CA 1 ATOM 2738 C C . PHE A 1 345 ? -5.300 3.962 7.938 1.00 2.00 ? 345 PHE A C 1 ATOM 2739 O O . PHE A 1 345 ? -5.418 2.870 8.525 1.00 2.00 ? 345 PHE A O 1 ATOM 2740 C CB . PHE A 1 345 ? -4.253 5.660 9.486 1.00 2.00 ? 345 PHE A CB 1 ATOM 2741 C CG . PHE A 1 345 ? -3.041 6.464 9.865 1.00 2.00 ? 345 PHE A CG 1 ATOM 2742 C CD1 . PHE A 1 345 ? -2.910 7.788 9.459 1.00 2.00 ? 345 PHE A CD1 1 ATOM 2743 C CD2 . PHE A 1 345 ? -2.022 5.898 10.621 1.00 2.00 ? 345 PHE A CD2 1 ATOM 2744 C CE1 . PHE A 1 345 ? -1.778 8.544 9.802 1.00 2.00 ? 345 PHE A CE1 1 ATOM 2745 C CE2 . PHE A 1 345 ? -0.884 6.641 10.971 1.00 2.00 ? 345 PHE A CE2 1 ATOM 2746 C CZ . PHE A 1 345 ? -0.766 7.968 10.558 1.00 2.00 ? 345 PHE A CZ 1 ATOM 2747 N N . ALA A 1 346 ? -6.189 4.427 7.074 1.00 2.00 ? 346 ALA A N 1 ATOM 2748 C CA . ALA A 1 346 ? -7.373 3.668 6.746 1.00 2.00 ? 346 ALA A CA 1 ATOM 2749 C C . ALA A 1 346 ? -6.964 2.570 5.803 1.00 2.36 ? 346 ALA A C 1 ATOM 2750 O O . ALA A 1 346 ? -7.499 1.466 5.854 1.00 2.93 ? 346 ALA A O 1 ATOM 2751 C CB . ALA A 1 346 ? -8.398 4.551 6.076 1.00 2.00 ? 346 ALA A CB 1 ATOM 2752 N N . PHE A 1 347 ? -6.000 2.865 4.942 1.00 2.00 ? 347 PHE A N 1 ATOM 2753 C CA . PHE A 1 347 ? -5.587 1.864 3.977 1.00 2.00 ? 347 PHE A CA 1 ATOM 2754 C C . PHE A 1 347 ? -4.781 0.731 4.608 1.00 2.00 ? 347 PHE A C 1 ATOM 2755 O O . PHE A 1 347 ? -4.700 -0.360 4.051 1.00 2.27 ? 347 PHE A O 1 ATOM 2756 C CB . PHE A 1 347 ? -4.807 2.515 2.826 1.00 2.00 ? 347 PHE A CB 1 ATOM 2757 C CG . PHE A 1 347 ? -5.013 1.841 1.486 1.00 2.00 ? 347 PHE A CG 1 ATOM 2758 C CD1 . PHE A 1 347 ? -5.618 0.591 1.396 1.00 2.30 ? 347 PHE A CD1 1 ATOM 2759 C CD2 . PHE A 1 347 ? -4.542 2.425 0.327 1.00 2.00 ? 347 PHE A CD2 1 ATOM 2760 C CE1 . PHE A 1 347 ? -5.741 -0.066 0.169 1.00 2.00 ? 347 PHE A CE1 1 ATOM 2761 C CE2 . PHE A 1 347 ? -4.659 1.777 -0.898 1.00 2.00 ? 347 PHE A CE2 1 ATOM 2762 C CZ . PHE A 1 347 ? -5.258 0.529 -0.977 1.00 2.00 ? 347 PHE A CZ 1 ATOM 2763 N N . ARG A 1 348 ? -4.207 0.959 5.781 1.00 2.00 ? 348 ARG A N 1 ATOM 2764 C CA . ARG A 1 348 ? -3.428 -0.097 6.410 1.00 2.00 ? 348 ARG A CA 1 ATOM 2765 C C . ARG A 1 348 ? -4.260 -1.303 6.844 1.00 2.00 ? 348 ARG A C 1 ATOM 2766 O O . ARG A 1 348 ? -3.750 -2.215 7.493 1.00 2.00 ? 348 ARG A O 1 ATOM 2767 C CB . ARG A 1 348 ? -2.673 0.458 7.602 1.00 2.00 ? 348 ARG A CB 1 ATOM 2768 C CG . ARG A 1 348 ? -1.892 1.684 7.266 1.00 2.00 ? 348 ARG A CG 1 ATOM 2769 C CD . ARG A 1 348 ? -1.012 2.055 8.412 1.00 2.00 ? 348 ARG A CD 1 ATOM 2770 N NE . ARG A 1 348 ? -0.310 3.302 8.161 1.00 2.00 ? 348 ARG A NE 1 ATOM 2771 C CZ . ARG A 1 348 ? 0.786 3.667 8.811 1.00 2.04 ? 348 ARG A CZ 1 ATOM 2772 N NH1 . ARG A 1 348 ? 1.295 2.871 9.747 1.00 2.00 ? 348 ARG A NH1 1 ATOM 2773 N NH2 . ARG A 1 348 ? 1.375 4.821 8.523 1.00 2.00 ? 348 ARG A NH2 1 ATOM 2774 N N . PHE A 1 349 ? -5.540 -1.312 6.491 1.00 2.00 ? 349 PHE A N 1 ATOM 2775 C CA . PHE A 1 349 ? -6.386 -2.433 6.857 1.00 2.00 ? 349 PHE A CA 1 ATOM 2776 C C . PHE A 1 349 ? -5.724 -3.673 6.270 1.00 2.06 ? 349 PHE A C 1 ATOM 2777 O O . PHE A 1 349 ? -5.814 -4.775 6.815 1.00 2.84 ? 349 PHE A O 1 ATOM 2778 C CB . PHE A 1 349 ? -7.797 -2.241 6.289 1.00 2.00 ? 349 PHE A CB 1 ATOM 2779 C CG . PHE A 1 349 ? -7.871 -2.301 4.782 1.00 2.00 ? 349 PHE A CG 1 ATOM 2780 C CD1 . PHE A 1 349 ? -7.923 -3.525 4.119 1.00 2.00 ? 349 PHE A CD1 1 ATOM 2781 C CD2 . PHE A 1 349 ? -7.897 -1.135 4.029 1.00 2.00 ? 349 PHE A CD2 1 ATOM 2782 C CE1 . PHE A 1 349 ? -8.000 -3.585 2.738 1.00 2.00 ? 349 PHE A CE1 1 ATOM 2783 C CE2 . PHE A 1 349 ? -7.973 -1.186 2.647 1.00 2.00 ? 349 PHE A CE2 1 ATOM 2784 C CZ . PHE A 1 349 ? -8.024 -2.413 2.000 1.00 2.00 ? 349 PHE A CZ 1 ATOM 2785 N N . GLY A 1 350 ? -5.032 -3.466 5.159 1.00 2.00 ? 350 GLY A N 1 ATOM 2786 C CA . GLY A 1 350 ? -4.356 -4.557 4.493 1.00 2.00 ? 350 GLY A CA 1 ATOM 2787 C C . GLY A 1 350 ? -3.254 -5.204 5.303 1.00 2.33 ? 350 GLY A C 1 ATOM 2788 O O . GLY A 1 350 ? -2.792 -6.278 4.930 1.00 3.14 ? 350 GLY A O 1 ATOM 2789 N N . HIS A 1 351 ? -2.819 -4.572 6.394 1.00 3.98 ? 351 HIS A N 1 ATOM 2790 C CA . HIS A 1 351 ? -1.756 -5.151 7.223 1.00 2.00 ? 351 HIS A CA 1 ATOM 2791 C C . HIS A 1 351 ? -2.276 -6.398 7.883 1.00 2.00 ? 351 HIS A C 1 ATOM 2792 O O . HIS A 1 351 ? -1.506 -7.225 8.360 1.00 2.00 ? 351 HIS A O 1 ATOM 2793 C CB . HIS A 1 351 ? -1.293 -4.177 8.308 1.00 2.00 ? 351 HIS A CB 1 ATOM 2794 C CG . HIS A 1 351 ? -0.237 -3.222 7.853 1.00 2.00 ? 351 HIS A CG 1 ATOM 2795 N ND1 . HIS A 1 351 ? 0.106 -2.095 8.569 1.00 2.09 ? 351 HIS A ND1 1 ATOM 2796 C CD2 . HIS A 1 351 ? 0.557 -3.227 6.756 1.00 2.00 ? 351 HIS A CD2 1 ATOM 2797 C CE1 . HIS A 1 351 ? 1.064 -1.447 7.931 1.00 2.92 ? 351 HIS A CE1 1 ATOM 2798 N NE2 . HIS A 1 351 ? 1.357 -2.113 6.829 1.00 2.00 ? 351 HIS A NE2 1 ATOM 2799 N N . MET A 1 352 ? -3.598 -6.521 7.892 1.00 2.00 ? 352 MET A N 1 ATOM 2800 C CA . MET A 1 352 ? -4.266 -7.654 8.502 1.00 2.00 ? 352 MET A CA 1 ATOM 2801 C C . MET A 1 352 ? -4.735 -8.679 7.479 1.00 2.00 ? 352 MET A C 1 ATOM 2802 O O . MET A 1 352 ? -5.635 -9.474 7.747 1.00 2.00 ? 352 MET A O 1 ATOM 2803 C CB . MET A 1 352 ? -5.437 -7.149 9.341 1.00 3.36 ? 352 MET A CB 1 ATOM 2804 C CG . MET A 1 352 ? -4.992 -6.233 10.475 1.00 2.66 ? 352 MET A CG 1 ATOM 2805 S SD . MET A 1 352 ? -6.296 -5.947 11.675 1.00 5.70 ? 352 MET A SD 1 ATOM 2806 C CE . MET A 1 352 ? -5.727 -4.399 12.464 1.00 3.00 ? 352 MET A CE 1 ATOM 2807 N N . GLU A 1 353 ? -4.105 -8.657 6.308 1.00 2.16 ? 353 GLU A N 1 ATOM 2808 C CA . GLU A 1 353 ? -4.432 -9.582 5.231 1.00 2.00 ? 353 GLU A CA 1 ATOM 2809 C C . GLU A 1 353 ? -3.189 -10.333 4.813 1.00 2.00 ? 353 GLU A C 1 ATOM 2810 O O . GLU A 1 353 ? -3.193 -11.071 3.840 1.00 2.00 ? 353 GLU A O 1 ATOM 2811 C CB . GLU A 1 353 ? -5.006 -8.831 4.035 1.00 2.00 ? 353 GLU A CB 1 ATOM 2812 C CG . GLU A 1 353 ? -6.274 -8.096 4.358 1.00 2.00 ? 353 GLU A CG 1 ATOM 2813 C CD . GLU A 1 353 ? -6.901 -7.496 3.145 1.00 2.00 ? 353 GLU A CD 1 ATOM 2814 O OE1 . GLU A 1 353 ? -6.148 -7.062 2.262 1.00 2.41 ? 353 GLU A OE1 1 ATOM 2815 O OE2 . GLU A 1 353 ? -8.140 -7.442 3.073 1.00 2.00 ? 353 GLU A OE2 1 ATOM 2816 N N . VAL A 1 354 ? -2.120 -10.129 5.565 1.00 2.00 ? 354 VAL A N 1 ATOM 2817 C CA . VAL A 1 354 ? -0.860 -10.795 5.305 1.00 2.00 ? 354 VAL A CA 1 ATOM 2818 C C . VAL A 1 354 ? -0.793 -12.115 6.059 1.00 2.36 ? 354 VAL A C 1 ATOM 2819 O O . VAL A 1 354 ? -0.723 -12.123 7.290 1.00 2.00 ? 354 VAL A O 1 ATOM 2820 C CB . VAL A 1 354 ? 0.297 -9.980 5.798 1.00 2.00 ? 354 VAL A CB 1 ATOM 2821 C CG1 . VAL A 1 354 ? 1.569 -10.674 5.403 1.00 3.07 ? 354 VAL A CG1 1 ATOM 2822 C CG2 . VAL A 1 354 ? 0.195 -8.564 5.287 1.00 2.00 ? 354 VAL A CG2 1 ATOM 2823 N N . PRO A 1 355 ? -0.775 -13.244 5.332 1.00 2.00 ? 355 PRO A N 1 ATOM 2824 C CA . PRO A 1 355 ? -0.715 -14.597 5.888 1.00 2.00 ? 355 PRO A CA 1 ATOM 2825 C C . PRO A 1 355 ? 0.661 -14.891 6.486 1.00 2.90 ? 355 PRO A C 1 ATOM 2826 O O . PRO A 1 355 ? 1.655 -14.264 6.110 1.00 3.20 ? 355 PRO A O 1 ATOM 2827 C CB . PRO A 1 355 ? -1.020 -15.457 4.683 1.00 2.00 ? 355 PRO A CB 1 ATOM 2828 C CG . PRO A 1 355 ? -0.287 -14.731 3.615 1.00 2.00 ? 355 PRO A CG 1 ATOM 2829 C CD . PRO A 1 355 ? -0.660 -13.288 3.866 1.00 2.00 ? 355 PRO A CD 1 ATOM 2830 N N . SER A 1 356 ? 0.720 -15.856 7.401 1.00 3.04 ? 356 SER A N 1 ATOM 2831 C CA . SER A 1 356 ? 1.967 -16.209 8.085 1.00 2.00 ? 356 SER A CA 1 ATOM 2832 C C . SER A 1 356 ? 3.161 -16.625 7.230 1.00 2.02 ? 356 SER A C 1 ATOM 2833 O O . SER A 1 356 ? 4.304 -16.366 7.609 1.00 2.32 ? 356 SER A O 1 ATOM 2834 C CB . SER A 1 356 ? 1.711 -17.329 9.086 1.00 2.10 ? 356 SER A CB 1 ATOM 2835 O OG . SER A 1 356 ? 1.526 -18.567 8.419 1.00 2.71 ? 356 SER A OG 1 ATOM 2836 N N . THR A 1 357 ? 2.909 -17.268 6.092 1.00 2.00 ? 357 THR A N 1 ATOM 2837 C CA . THR A 1 357 ? 3.997 -17.745 5.245 1.00 2.00 ? 357 THR A CA 1 ATOM 2838 C C . THR A 1 357 ? 3.872 -17.338 3.788 1.00 2.00 ? 357 THR A C 1 ATOM 2839 O O . THR A 1 357 ? 2.816 -16.900 3.352 1.00 3.40 ? 357 THR A O 1 ATOM 2840 C CB . THR A 1 357 ? 4.045 -19.260 5.241 1.00 2.13 ? 357 THR A CB 1 ATOM 2841 O OG1 . THR A 1 357 ? 3.062 -19.749 4.318 1.00 5.01 ? 357 THR A OG1 1 ATOM 2842 C CG2 . THR A 1 357 ? 3.726 -19.805 6.615 1.00 2.81 ? 357 THR A CG2 1 ATOM 2843 N N . VAL A 1 358 ? 4.960 -17.523 3.040 1.00 2.51 ? 358 VAL A N 1 ATOM 2844 C CA . VAL A 1 358 ? 5.020 -17.226 1.604 1.00 2.00 ? 358 VAL A CA 1 ATOM 2845 C C . VAL A 1 358 ? 5.513 -18.486 0.879 1.00 2.00 ? 358 VAL A C 1 ATOM 2846 O O . VAL A 1 358 ? 6.579 -19.009 1.196 1.00 2.00 ? 358 VAL A O 1 ATOM 2847 C CB . VAL A 1 358 ? 5.982 -16.045 1.311 1.00 2.00 ? 358 VAL A CB 1 ATOM 2848 C CG1 . VAL A 1 358 ? 6.481 -16.120 -0.114 1.00 2.00 ? 358 VAL A CG1 1 ATOM 2849 C CG2 . VAL A 1 358 ? 5.265 -14.716 1.534 1.00 2.00 ? 358 VAL A CG2 1 ATOM 2850 N N . SER A 1 359 ? 4.737 -18.958 -0.097 1.00 3.42 ? 359 SER A N 1 ATOM 2851 C CA . SER A 1 359 ? 5.054 -20.181 -0.852 1.00 3.26 ? 359 SER A CA 1 ATOM 2852 C C . SER A 1 359 ? 5.738 -20.028 -2.207 1.00 3.74 ? 359 SER A C 1 ATOM 2853 O O . SER A 1 359 ? 5.793 -18.938 -2.775 1.00 6.42 ? 359 SER A O 1 ATOM 2854 C CB . SER A 1 359 ? 3.779 -20.999 -1.072 1.00 3.93 ? 359 SER A CB 1 ATOM 2855 O OG . SER A 1 359 ? 3.777 -22.165 -0.271 1.00 6.39 ? 359 SER A OG 1 ATOM 2856 N N . ARG A 1 360 ? 6.237 -21.154 -2.719 1.00 3.51 ? 360 ARG A N 1 ATOM 2857 C CA . ARG A 1 360 ? 6.918 -21.239 -4.018 1.00 3.08 ? 360 ARG A CA 1 ATOM 2858 C C . ARG A 1 360 ? 6.462 -22.513 -4.744 1.00 3.87 ? 360 ARG A C 1 ATOM 2859 O O . ARG A 1 360 ? 6.685 -23.621 -4.260 1.00 3.70 ? 360 ARG A O 1 ATOM 2860 C CB . ARG A 1 360 ? 8.442 -21.272 -3.823 1.00 2.06 ? 360 ARG A CB 1 ATOM 2861 C CG . ARG A 1 360 ? 9.156 -19.956 -4.115 1.00 2.00 ? 360 ARG A CG 1 ATOM 2862 C CD . ARG A 1 360 ? 9.732 -19.296 -2.865 1.00 2.00 ? 360 ARG A CD 1 ATOM 2863 N NE . ARG A 1 360 ? 11.068 -19.773 -2.500 1.00 2.01 ? 360 ARG A NE 1 ATOM 2864 C CZ . ARG A 1 360 ? 11.350 -21.005 -2.085 1.00 2.00 ? 360 ARG A CZ 1 ATOM 2865 N NH1 . ARG A 1 360 ? 10.390 -21.911 -1.977 1.00 2.00 ? 360 ARG A NH1 1 ATOM 2866 N NH2 . ARG A 1 360 ? 12.596 -21.326 -1.763 1.00 2.00 ? 360 ARG A NH2 1 ATOM 2867 N N . LEU A 1 361 ? 5.853 -22.367 -5.917 1.00 3.68 ? 361 LEU A N 1 ATOM 2868 C CA . LEU A 1 361 ? 5.352 -23.531 -6.634 1.00 3.76 ? 361 LEU A CA 1 ATOM 2869 C C . LEU A 1 361 ? 6.026 -23.881 -7.911 1.00 6.60 ? 361 LEU A C 1 ATOM 2870 O O . LEU A 1 361 ? 6.469 -23.028 -8.699 1.00 5.60 ? 361 LEU A O 1 ATOM 2871 C CB . LEU A 1 361 ? 3.865 -23.354 -6.921 1.00 4.35 ? 361 LEU A CB 1 ATOM 2872 C CG . LEU A 1 361 ? 2.935 -22.869 -5.814 1.00 3.61 ? 361 LEU A CG 1 ATOM 2873 C CD1 . LEU A 1 361 ? 1.532 -22.658 -6.346 1.00 2.27 ? 361 LEU A CD1 1 ATOM 2874 C CD2 . LEU A 1 361 ? 2.930 -23.837 -4.643 1.00 4.62 ? 361 LEU A CD2 1 ATOM 2875 N N . ASP A 1 362 ? 6.093 -25.164 -8.113 1.00 8.88 ? 362 ASP A N 1 ATOM 2876 C CA . ASP A 1 362 ? 6.697 -25.885 -9.263 1.00 8.80 ? 362 ASP A CA 1 ATOM 2877 C C . ASP A 1 362 ? 5.787 -25.871 -10.519 1.00 7.18 ? 362 ASP A C 1 ATOM 2878 O O . ASP A 1 362 ? 4.558 -25.826 -10.336 1.00 2.77 ? 362 ASP A O 1 ATOM 2879 C CB . ASP A 1 362 ? 6.929 -27.321 -8.842 1.00 14.36 ? 362 ASP A CB 1 ATOM 2880 C CG . ASP A 1 362 ? 7.248 -28.216 -10.020 1.00 19.20 ? 362 ASP A CG 1 ATOM 2881 O OD1 . ASP A 1 362 ? 7.761 -27.697 -11.041 1.00 20.85 ? 362 ASP A OD1 1 ATOM 2882 O OD2 . ASP A 1 362 ? 6.984 -29.419 -9.924 1.00 21.47 ? 362 ASP A OD2 1 ATOM 2883 N N . GLU A 1 363 ? 6.219 -25.907 -11.783 1.00 8.80 ? 363 GLU A N 1 ATOM 2884 C CA . GLU A 1 363 ? 5.228 -25.680 -12.881 1.00 10.83 ? 363 GLU A CA 1 ATOM 2885 C C . GLU A 1 363 ? 3.910 -26.487 -12.851 1.00 10.54 ? 363 GLU A C 1 ATOM 2886 O O . GLU A 1 363 ? 3.106 -26.324 -13.755 1.00 10.55 ? 363 GLU A O 1 ATOM 2887 C CB . GLU A 1 363 ? 5.883 -25.929 -14.224 1.00 13.06 ? 363 GLU A CB 1 ATOM 2888 C CG . GLU A 1 363 ? 7.105 -26.799 -14.123 1.00 19.10 ? 363 GLU A CG 1 ATOM 2889 C CD . GLU A 1 363 ? 8.375 -26.059 -14.505 1.00 22.04 ? 363 GLU A CD 1 ATOM 2890 O OE1 . GLU A 1 363 ? 9.362 -26.146 -13.758 1.00 24.57 ? 363 GLU A OE1 1 ATOM 2891 O OE2 . GLU A 1 363 ? 8.379 -25.404 -15.560 1.00 22.91 ? 363 GLU A OE2 1 ATOM 2892 N N . ASN A 1 364 ? 3.653 -27.344 -11.876 1.00 9.01 ? 364 ASN A N 1 ATOM 2893 C CA . ASN A 1 364 ? 2.408 -28.087 -11.860 1.00 8.89 ? 364 ASN A CA 1 ATOM 2894 C C . ASN A 1 364 ? 1.674 -27.537 -10.641 1.00 9.95 ? 364 ASN A C 1 ATOM 2895 O O . ASN A 1 364 ? 0.702 -28.118 -10.150 1.00 8.75 ? 364 ASN A O 1 ATOM 2896 C CB . ASN A 1 364 ? 2.696 -29.572 -11.700 1.00 9.60 ? 364 ASN A CB 1 ATOM 2897 C CG . ASN A 1 364 ? 3.089 -30.223 -13.000 1.00 8.25 ? 364 ASN A CG 1 ATOM 2898 O OD1 . ASN A 1 364 ? 3.691 -31.295 -13.012 1.00 7.85 ? 364 ASN A OD1 1 ATOM 2899 N ND2 . ASN A 1 364 ? 2.735 -29.585 -14.109 1.00 8.89 ? 364 ASN A ND2 1 ATOM 2900 N N . TYR A 1 365 ? 2.161 -26.387 -10.176 1.00 10.05 ? 365 TYR A N 1 ATOM 2901 C CA . TYR A 1 365 ? 1.627 -25.726 -9.001 1.00 9.12 ? 365 TYR A CA 1 ATOM 2902 C C . TYR A 1 365 ? 1.679 -26.711 -7.851 1.00 11.30 ? 365 TYR A C 1 ATOM 2903 O O . TYR A 1 365 ? 0.702 -26.926 -7.132 1.00 13.26 ? 365 TYR A O 1 ATOM 2904 C CB . TYR A 1 365 ? 0.209 -25.255 -9.250 1.00 7.97 ? 365 TYR A CB 1 ATOM 2905 C CG . TYR A 1 365 ? 0.149 -24.027 -10.119 1.00 7.15 ? 365 TYR A CG 1 ATOM 2906 C CD1 . TYR A 1 365 ? 0.111 -22.749 -9.564 1.00 5.90 ? 365 TYR A CD1 1 ATOM 2907 C CD2 . TYR A 1 365 ? 0.106 -24.142 -11.500 1.00 6.96 ? 365 TYR A CD2 1 ATOM 2908 C CE1 . TYR A 1 365 ? 0.022 -21.619 -10.374 1.00 3.63 ? 365 TYR A CE1 1 ATOM 2909 C CE2 . TYR A 1 365 ? 0.018 -23.023 -12.311 1.00 5.52 ? 365 TYR A CE2 1 ATOM 2910 C CZ . TYR A 1 365 ? -0.027 -21.769 -11.748 1.00 4.02 ? 365 TYR A CZ 1 ATOM 2911 O OH . TYR A 1 365 ? -0.146 -20.683 -12.583 1.00 2.60 ? 365 TYR A OH 1 ATOM 2912 N N . GLN A 1 366 ? 2.847 -27.325 -7.715 1.00 11.37 ? 366 GLN A N 1 ATOM 2913 C CA . GLN A 1 366 ? 3.129 -28.283 -6.665 1.00 10.59 ? 366 GLN A CA 1 ATOM 2914 C C . GLN A 1 366 ? 4.227 -27.612 -5.855 1.00 10.27 ? 366 GLN A C 1 ATOM 2915 O O . GLN A 1 366 ? 5.028 -26.869 -6.409 1.00 10.11 ? 366 GLN A O 1 ATOM 2916 C CB . GLN A 1 366 ? 3.638 -29.583 -7.286 1.00 13.70 ? 366 GLN A CB 1 ATOM 2917 C CG . GLN A 1 366 ? 2.594 -30.316 -8.114 1.00 15.56 ? 366 GLN A CG 1 ATOM 2918 C CD . GLN A 1 366 ? 1.399 -30.739 -7.274 1.00 18.07 ? 366 GLN A CD 1 ATOM 2919 O OE1 . GLN A 1 366 ? 0.694 -29.898 -6.708 1.00 18.69 ? 366 GLN A OE1 1 ATOM 2920 N NE2 . GLN A 1 366 ? 1.172 -32.047 -7.178 1.00 19.34 ? 366 GLN A NE2 1 ATOM 2921 N N . PRO A 1 367 ? 4.274 -27.837 -4.532 1.00 10.56 ? 367 PRO A N 1 ATOM 2922 C CA . PRO A 1 367 ? 5.343 -27.178 -3.769 1.00 9.96 ? 367 PRO A CA 1 ATOM 2923 C C . PRO A 1 367 ? 6.676 -27.500 -4.431 1.00 9.72 ? 367 PRO A C 1 ATOM 2924 O O . PRO A 1 367 ? 7.045 -28.665 -4.529 1.00 10.65 ? 367 PRO A O 1 ATOM 2925 C CB . PRO A 1 367 ? 5.221 -27.810 -2.385 1.00 8.83 ? 367 PRO A CB 1 ATOM 2926 C CG . PRO A 1 367 ? 3.768 -28.129 -2.285 1.00 9.08 ? 367 PRO A CG 1 ATOM 2927 C CD . PRO A 1 367 ? 3.453 -28.691 -3.658 1.00 10.06 ? 367 PRO A CD 1 ATOM 2928 N N . ARG A 1 368 ? 7.406 -26.496 -4.897 1.00 9.53 ? 368 ARG A N 1 ATOM 2929 C CA . ARG A 1 368 ? 8.657 -26.829 -5.549 1.00 11.02 ? 368 ARG A CA 1 ATOM 2930 C C . ARG A 1 368 ? 9.907 -26.707 -4.689 1.00 11.62 ? 368 ARG A C 1 ATOM 2931 O O . ARG A 1 368 ? 10.419 -25.612 -4.422 1.00 10.09 ? 368 ARG A O 1 ATOM 2932 C CB . ARG A 1 368 ? 8.829 -26.032 -6.855 1.00 10.78 ? 368 ARG A CB 1 ATOM 2933 C CG . ARG A 1 368 ? 9.558 -24.709 -6.731 1.00 11.38 ? 368 ARG A CG 1 ATOM 2934 C CD . ARG A 1 368 ? 10.010 -24.180 -8.092 1.00 11.71 ? 368 ARG A CD 1 ATOM 2935 N NE . ARG A 1 368 ? 11.465 -24.090 -8.262 1.00 11.54 ? 368 ARG A NE 1 ATOM 2936 C CZ . ARG A 1 368 ? 12.338 -23.782 -7.299 1.00 12.85 ? 368 ARG A CZ 1 ATOM 2937 N NH1 . ARG A 1 368 ? 11.934 -23.539 -6.055 1.00 11.81 ? 368 ARG A NH1 1 ATOM 2938 N NH2 . ARG A 1 368 ? 13.630 -23.684 -7.590 1.00 12.20 ? 368 ARG A NH2 1 ATOM 2939 N N . GLY A 1 369 ? 10.396 -27.853 -4.241 1.00 12.34 ? 369 GLY A N 1 ATOM 2940 C CA . GLY A 1 369 ? 11.610 -27.825 -3.465 1.00 15.37 ? 369 GLY A CA 1 ATOM 2941 C C . GLY A 1 369 ? 11.554 -28.315 -2.042 1.00 16.46 ? 369 GLY A C 1 ATOM 2942 O O . GLY A 1 369 ? 10.479 -28.507 -1.474 1.00 16.74 ? 369 GLY A O 1 ATOM 2943 N N . PRO A 1 370 ? 12.739 -28.516 -1.444 1.00 17.41 ? 370 PRO A N 1 ATOM 2944 C CA . PRO A 1 370 ? 12.981 -28.985 -0.076 1.00 17.02 ? 370 PRO A CA 1 ATOM 2945 C C . PRO A 1 370 ? 12.547 -27.931 0.943 1.00 18.06 ? 370 PRO A C 1 ATOM 2946 O O . PRO A 1 370 ? 12.292 -28.236 2.114 1.00 17.37 ? 370 PRO A O 1 ATOM 2947 C CB . PRO A 1 370 ? 14.488 -29.191 -0.063 1.00 17.48 ? 370 PRO A CB 1 ATOM 2948 C CG . PRO A 1 370 ? 14.967 -28.044 -0.944 1.00 16.50 ? 370 PRO A CG 1 ATOM 2949 C CD . PRO A 1 370 ? 14.013 -28.155 -2.104 1.00 16.58 ? 370 PRO A CD 1 ATOM 2950 N N . GLU A 1 371 ? 12.480 -26.686 0.478 1.00 18.42 ? 371 GLU A N 1 ATOM 2951 C CA . GLU A 1 371 ? 12.100 -25.561 1.319 1.00 17.74 ? 371 GLU A CA 1 ATOM 2952 C C . GLU A 1 371 ? 11.207 -24.614 0.512 1.00 15.88 ? 371 GLU A C 1 ATOM 2953 O O . GLU A 1 371 ? 11.573 -23.468 0.233 1.00 15.35 ? 371 GLU A O 1 ATOM 2954 C CB . GLU A 1 371 ? 13.362 -24.833 1.807 1.00 19.38 ? 371 GLU A CB 1 ATOM 2955 C CG . GLU A 1 371 ? 14.505 -25.777 2.199 1.00 22.22 ? 371 GLU A CG 1 ATOM 2956 C CD . GLU A 1 371 ? 15.715 -25.048 2.761 1.00 23.88 ? 371 GLU A CD 1 ATOM 2957 O OE1 . GLU A 1 371 ? 16.097 -23.998 2.199 1.00 24.47 ? 371 GLU A OE1 1 ATOM 2958 O OE2 . GLU A 1 371 ? 16.294 -25.535 3.760 1.00 25.52 ? 371 GLU A OE2 1 ATOM 2959 N N . ALA A 1 372 ? 10.032 -25.115 0.141 1.00 13.48 ? 372 ALA A N 1 ATOM 2960 C CA . ALA A 1 372 ? 9.065 -24.348 -0.631 1.00 12.17 ? 372 ALA A CA 1 ATOM 2961 C C . ALA A 1 372 ? 8.340 -23.282 0.194 1.00 11.62 ? 372 ALA A C 1 ATOM 2962 O O . ALA A 1 372 ? 8.256 -22.127 -0.229 1.00 12.99 ? 372 ALA A O 1 ATOM 2963 C CB . ALA A 1 372 ? 8.052 -25.286 -1.255 1.00 13.18 ? 372 ALA A CB 1 ATOM 2964 N N . GLU A 1 373 ? 7.804 -23.673 1.353 1.00 8.23 ? 373 GLU A N 1 ATOM 2965 C CA . GLU A 1 373 ? 7.087 -22.743 2.228 1.00 5.33 ? 373 GLU A CA 1 ATOM 2966 C C . GLU A 1 373 ? 8.058 -22.041 3.138 1.00 4.02 ? 373 GLU A C 1 ATOM 2967 O O . GLU A 1 373 ? 8.645 -22.660 4.014 1.00 5.46 ? 373 GLU A O 1 ATOM 2968 C CB . GLU A 1 373 ? 6.079 -23.468 3.099 1.00 5.79 ? 373 GLU A CB 1 ATOM 2969 C CG . GLU A 1 373 ? 4.653 -23.236 2.707 1.00 10.05 ? 373 GLU A CG 1 ATOM 2970 C CD . GLU A 1 373 ? 3.717 -23.378 3.888 1.00 12.30 ? 373 GLU A CD 1 ATOM 2971 O OE1 . GLU A 1 373 ? 3.648 -22.437 4.711 1.00 12.73 ? 373 GLU A OE1 1 ATOM 2972 O OE2 . GLU A 1 373 ? 3.060 -24.435 4.002 1.00 14.87 ? 373 GLU A OE2 1 ATOM 2973 N N . LEU A 1 374 ? 8.213 -20.742 2.952 1.00 2.60 ? 374 LEU A N 1 ATOM 2974 C CA . LEU A 1 374 ? 9.147 -19.994 3.766 1.00 2.00 ? 374 LEU A CA 1 ATOM 2975 C C . LEU A 1 374 ? 8.438 -19.061 4.750 1.00 2.00 ? 374 LEU A C 1 ATOM 2976 O O . LEU A 1 374 ? 7.523 -18.326 4.371 1.00 2.39 ? 374 LEU A O 1 ATOM 2977 C CB . LEU A 1 374 ? 10.082 -19.195 2.846 1.00 2.12 ? 374 LEU A CB 1 ATOM 2978 C CG . LEU A 1 374 ? 11.044 -19.966 1.931 1.00 2.00 ? 374 LEU A CG 1 ATOM 2979 C CD1 . LEU A 1 374 ? 11.622 -19.054 0.860 1.00 2.00 ? 374 LEU A CD1 1 ATOM 2980 C CD2 . LEU A 1 374 ? 12.152 -20.553 2.768 1.00 2.43 ? 374 LEU A CD2 1 ATOM 2981 N N . PRO A 1 375 ? 8.831 -19.101 6.039 1.00 2.00 ? 375 PRO A N 1 ATOM 2982 C CA . PRO A 1 375 ? 8.179 -18.212 6.999 1.00 2.25 ? 375 PRO A CA 1 ATOM 2983 C C . PRO A 1 375 ? 8.415 -16.786 6.516 1.00 2.85 ? 375 PRO A C 1 ATOM 2984 O O . PRO A 1 375 ? 9.539 -16.408 6.166 1.00 2.00 ? 375 PRO A O 1 ATOM 2985 C CB . PRO A 1 375 ? 8.897 -18.529 8.313 1.00 2.00 ? 375 PRO A CB 1 ATOM 2986 C CG . PRO A 1 375 ? 10.253 -18.945 7.867 1.00 2.00 ? 375 PRO A CG 1 ATOM 2987 C CD . PRO A 1 375 ? 9.929 -19.838 6.686 1.00 2.51 ? 375 PRO A CD 1 ATOM 2988 N N . LEU A 1 376 ? 7.345 -16.002 6.488 1.00 2.70 ? 376 LEU A N 1 ATOM 2989 C CA . LEU A 1 376 ? 7.433 -14.642 6.003 1.00 2.00 ? 376 LEU A CA 1 ATOM 2990 C C . LEU A 1 376 ? 8.585 -13.806 6.548 1.00 2.07 ? 376 LEU A C 1 ATOM 2991 O O . LEU A 1 376 ? 9.372 -13.242 5.790 1.00 2.73 ? 376 LEU A O 1 ATOM 2992 C CB . LEU A 1 376 ? 6.148 -13.869 6.317 1.00 3.38 ? 376 LEU A CB 1 ATOM 2993 C CG . LEU A 1 376 ? 5.782 -12.714 5.365 1.00 3.54 ? 376 LEU A CG 1 ATOM 2994 C CD1 . LEU A 1 376 ? 4.919 -11.685 6.075 1.00 2.00 ? 376 LEU A CD1 1 ATOM 2995 C CD2 . LEU A 1 376 ? 7.051 -12.076 4.808 1.00 2.00 ? 376 LEU A CD2 1 ATOM 2996 N N . HIS A 1 377 ? 8.653 -13.752 7.862 1.00 2.63 ? 377 HIS A N 1 ATOM 2997 C CA . HIS A 1 377 ? 9.648 -12.927 8.535 1.00 2.56 ? 377 HIS A CA 1 ATOM 2998 C C . HIS A 1 377 ? 11.082 -12.989 7.970 1.00 2.00 ? 377 HIS A C 1 ATOM 2999 O O . HIS A 1 377 ? 11.822 -12.012 8.117 1.00 2.00 ? 377 HIS A O 1 ATOM 3000 C CB . HIS A 1 377 ? 9.611 -13.310 9.989 1.00 2.00 ? 377 HIS A CB 1 ATOM 3001 C CG . HIS A 1 377 ? 10.708 -14.299 10.407 1.00 2.00 ? 377 HIS A CG 1 ATOM 3002 N ND1 . HIS A 1 377 ? 10.594 -15.667 10.237 1.00 2.00 ? 377 HIS A ND1 1 ATOM 3003 C CD2 . HIS A 1 377 ? 11.905 -14.053 10.958 1.00 2.00 ? 377 HIS A CD2 1 ATOM 3004 C CE1 . HIS A 1 377 ? 11.722 -16.222 10.657 1.00 2.00 ? 377 HIS A CE1 1 ATOM 3005 N NE2 . HIS A 1 377 ? 12.516 -15.266 11.100 1.00 2.00 ? 377 HIS A NE2 1 ATOM 3006 N N . THR A 1 378 ? 11.464 -14.106 7.311 1.00 2.00 ? 378 THR A N 1 ATOM 3007 C CA . THR A 1 378 ? 12.807 -14.215 6.682 1.00 2.00 ? 378 THR A CA 1 ATOM 3008 C C . THR A 1 378 ? 12.762 -13.767 5.233 1.00 2.34 ? 378 THR A C 1 ATOM 3009 O O . THR A 1 378 ? 13.588 -14.169 4.418 1.00 2.97 ? 378 THR A O 1 ATOM 3010 C CB . THR A 1 378 ? 13.325 -15.647 6.732 1.00 2.00 ? 378 THR A CB 1 ATOM 3011 O OG1 . THR A 1 378 ? 12.617 -16.450 5.779 1.00 2.00 ? 378 THR A OG1 1 ATOM 3012 C CG2 . THR A 1 378 ? 13.151 -16.212 8.143 1.00 2.00 ? 378 THR A CG2 1 ATOM 3013 N N . LEU A 1 379 ? 11.795 -12.921 4.917 1.00 2.00 ? 379 LEU A N 1 ATOM 3014 C CA . LEU A 1 379 ? 11.644 -12.451 3.557 1.00 2.03 ? 379 LEU A CA 1 ATOM 3015 C C . LEU A 1 379 ? 11.592 -10.940 3.429 1.00 2.65 ? 379 LEU A C 1 ATOM 3016 O O . LEU A 1 379 ? 11.613 -10.426 2.316 1.00 3.63 ? 379 LEU A O 1 ATOM 3017 C CB . LEU A 1 379 ? 10.393 -13.064 2.925 1.00 2.00 ? 379 LEU A CB 1 ATOM 3018 C CG . LEU A 1 379 ? 10.484 -14.529 2.507 1.00 2.00 ? 379 LEU A CG 1 ATOM 3019 C CD1 . LEU A 1 379 ? 9.096 -15.083 2.288 1.00 2.00 ? 379 LEU A CD1 1 ATOM 3020 C CD2 . LEU A 1 379 ? 11.308 -14.651 1.249 1.00 2.00 ? 379 LEU A CD2 1 ATOM 3021 N N . PHE A 1 380 ? 11.508 -10.210 4.536 1.00 2.00 ? 380 PHE A N 1 ATOM 3022 C CA . PHE A 1 380 ? 11.497 -8.760 4.392 1.00 2.00 ? 380 PHE A CA 1 ATOM 3023 C C . PHE A 1 380 ? 12.868 -8.400 3.828 1.00 2.33 ? 380 PHE A C 1 ATOM 3024 O O . PHE A 1 380 ? 13.894 -8.901 4.289 1.00 2.92 ? 380 PHE A O 1 ATOM 3025 C CB . PHE A 1 380 ? 11.294 -8.044 5.731 1.00 2.00 ? 380 PHE A CB 1 ATOM 3026 C CG . PHE A 1 380 ? 10.088 -8.496 6.475 1.00 2.00 ? 380 PHE A CG 1 ATOM 3027 C CD1 . PHE A 1 380 ? 8.834 -8.416 5.904 1.00 2.00 ? 380 PHE A CD1 1 ATOM 3028 C CD2 . PHE A 1 380 ? 10.212 -9.051 7.736 1.00 2.64 ? 380 PHE A CD2 1 ATOM 3029 C CE1 . PHE A 1 380 ? 7.716 -8.892 6.581 1.00 2.00 ? 380 PHE A CE1 1 ATOM 3030 C CE2 . PHE A 1 380 ? 9.106 -9.526 8.416 1.00 2.00 ? 380 PHE A CE2 1 ATOM 3031 C CZ . PHE A 1 380 ? 7.853 -9.448 7.835 1.00 2.00 ? 380 PHE A CZ 1 ATOM 3032 N N . PHE A 1 381 ? 12.881 -7.554 2.810 1.00 2.20 ? 381 PHE A N 1 ATOM 3033 C CA . PHE A 1 381 ? 14.125 -7.129 2.195 1.00 3.14 ? 381 PHE A CA 1 ATOM 3034 C C . PHE A 1 381 ? 14.948 -8.248 1.566 1.00 2.03 ? 381 PHE A C 1 ATOM 3035 O O . PHE A 1 381 ? 16.161 -8.115 1.414 1.00 2.04 ? 381 PHE A O 1 ATOM 3036 C CB . PHE A 1 381 ? 14.958 -6.371 3.226 1.00 2.08 ? 381 PHE A CB 1 ATOM 3037 C CG . PHE A 1 381 ? 14.392 -5.029 3.572 1.00 3.60 ? 381 PHE A CG 1 ATOM 3038 C CD1 . PHE A 1 381 ? 14.405 -3.998 2.636 1.00 4.90 ? 381 PHE A CD1 1 ATOM 3039 C CD2 . PHE A 1 381 ? 13.835 -4.791 4.820 1.00 4.19 ? 381 PHE A CD2 1 ATOM 3040 C CE1 . PHE A 1 381 ? 13.876 -2.745 2.936 1.00 4.41 ? 381 PHE A CE1 1 ATOM 3041 C CE2 . PHE A 1 381 ? 13.301 -3.539 5.132 1.00 5.14 ? 381 PHE A CE2 1 ATOM 3042 C CZ . PHE A 1 381 ? 13.324 -2.516 4.185 1.00 4.98 ? 381 PHE A CZ 1 ATOM 3043 N N . ASN A 1 382 ? 14.294 -9.338 1.173 1.00 2.43 ? 382 ASN A N 1 ATOM 3044 C CA . ASN A 1 382 ? 15.011 -10.451 0.555 1.00 3.02 ? 382 ASN A CA 1 ATOM 3045 C C . ASN A 1 382 ? 15.056 -10.338 -0.970 1.00 3.81 ? 382 ASN A C 1 ATOM 3046 O O . ASN A 1 382 ? 14.048 -10.066 -1.613 1.00 5.31 ? 382 ASN A O 1 ATOM 3047 C CB . ASN A 1 382 ? 14.382 -11.778 0.959 1.00 2.00 ? 382 ASN A CB 1 ATOM 3048 C CG . ASN A 1 382 ? 15.345 -12.927 0.828 1.00 2.00 ? 382 ASN A CG 1 ATOM 3049 O OD1 . ASN A 1 382 ? 15.648 -13.377 -0.273 1.00 3.19 ? 382 ASN A OD1 1 ATOM 3050 N ND2 . ASN A 1 382 ? 15.856 -13.399 1.958 1.00 2.68 ? 382 ASN A ND2 1 ATOM 3051 N N . THR A 1 383 ? 16.233 -10.556 -1.542 1.00 3.11 ? 383 THR A N 1 ATOM 3052 C CA . THR A 1 383 ? 16.418 -10.456 -2.979 1.00 2.00 ? 383 THR A CA 1 ATOM 3053 C C . THR A 1 383 ? 17.060 -11.702 -3.571 1.00 2.90 ? 383 THR A C 1 ATOM 3054 O O . THR A 1 383 ? 16.712 -12.128 -4.684 1.00 2.00 ? 383 THR A O 1 ATOM 3055 C CB . THR A 1 383 ? 17.309 -9.260 -3.314 1.00 2.00 ? 383 THR A CB 1 ATOM 3056 O OG1 . THR A 1 383 ? 18.341 -9.157 -2.323 1.00 2.94 ? 383 THR A OG1 1 ATOM 3057 C CG2 . THR A 1 383 ? 16.503 -7.979 -3.351 1.00 2.00 ? 383 THR A CG2 1 ATOM 3058 N N . TRP A 1 384 ? 18.002 -12.286 -2.832 1.00 3.02 ? 384 TRP A N 1 ATOM 3059 C CA . TRP A 1 384 ? 18.685 -13.466 -3.332 1.00 2.44 ? 384 TRP A CA 1 ATOM 3060 C C . TRP A 1 384 ? 17.733 -14.609 -3.585 1.00 2.35 ? 384 TRP A C 1 ATOM 3061 O O . TRP A 1 384 ? 17.857 -15.298 -4.599 1.00 3.39 ? 384 TRP A O 1 ATOM 3062 C CB . TRP A 1 384 ? 19.796 -13.909 -2.392 1.00 2.63 ? 384 TRP A CB 1 ATOM 3063 C CG . TRP A 1 384 ? 19.370 -14.289 -1.039 1.00 2.81 ? 384 TRP A CG 1 ATOM 3064 C CD1 . TRP A 1 384 ? 19.187 -13.459 0.025 1.00 4.28 ? 384 TRP A CD1 1 ATOM 3065 C CD2 . TRP A 1 384 ? 19.184 -15.617 -0.552 1.00 2.43 ? 384 TRP A CD2 1 ATOM 3066 N NE1 . TRP A 1 384 ? 18.910 -14.192 1.156 1.00 3.69 ? 384 TRP A NE1 1 ATOM 3067 C CE2 . TRP A 1 384 ? 18.902 -15.521 0.825 1.00 2.77 ? 384 TRP A CE2 1 ATOM 3068 C CE3 . TRP A 1 384 ? 19.232 -16.881 -1.145 1.00 2.21 ? 384 TRP A CE3 1 ATOM 3069 C CZ2 . TRP A 1 384 ? 18.674 -16.640 1.618 1.00 3.09 ? 384 TRP A CZ2 1 ATOM 3070 C CZ3 . TRP A 1 384 ? 19.006 -17.992 -0.359 1.00 2.26 ? 384 TRP A CZ3 1 ATOM 3071 C CH2 . TRP A 1 384 ? 18.729 -17.865 1.010 1.00 3.34 ? 384 TRP A CH2 1 ATOM 3072 N N . ARG A 1 385 ? 16.780 -14.816 -2.680 1.00 2.05 ? 385 ARG A N 1 ATOM 3073 C CA . ARG A 1 385 ? 15.800 -15.880 -2.882 1.00 3.31 ? 385 ARG A CA 1 ATOM 3074 C C . ARG A 1 385 ? 15.117 -15.730 -4.246 1.00 3.00 ? 385 ARG A C 1 ATOM 3075 O O . ARG A 1 385 ? 14.407 -16.635 -4.690 1.00 2.19 ? 385 ARG A O 1 ATOM 3076 C CB . ARG A 1 385 ? 14.747 -15.877 -1.774 1.00 2.00 ? 385 ARG A CB 1 ATOM 3077 C CG . ARG A 1 385 ? 15.197 -16.554 -0.507 1.00 2.00 ? 385 ARG A CG 1 ATOM 3078 C CD . ARG A 1 385 ? 15.442 -18.039 -0.730 1.00 3.01 ? 385 ARG A CD 1 ATOM 3079 N NE . ARG A 1 385 ? 15.569 -18.747 0.543 1.00 3.91 ? 385 ARG A NE 1 ATOM 3080 C CZ . ARG A 1 385 ? 15.786 -20.052 0.666 1.00 3.34 ? 385 ARG A CZ 1 ATOM 3081 N NH1 . ARG A 1 385 ? 15.907 -20.820 -0.413 1.00 3.59 ? 385 ARG A NH1 1 ATOM 3082 N NH2 . ARG A 1 385 ? 15.887 -20.586 1.876 1.00 2.40 ? 385 ARG A NH2 1 ATOM 3083 N N . ILE A 1 386 ? 15.323 -14.587 -4.901 1.00 2.64 ? 386 ILE A N 1 ATOM 3084 C CA . ILE A 1 386 ? 14.753 -14.364 -6.227 1.00 3.01 ? 386 ILE A CA 1 ATOM 3085 C C . ILE A 1 386 ? 15.820 -14.610 -7.273 1.00 2.94 ? 386 ILE A C 1 ATOM 3086 O O . ILE A 1 386 ? 15.788 -15.588 -8.024 1.00 2.00 ? 386 ILE A O 1 ATOM 3087 C CB . ILE A 1 386 ? 14.318 -12.914 -6.487 1.00 2.00 ? 386 ILE A CB 1 ATOM 3088 C CG1 . ILE A 1 386 ? 13.138 -12.510 -5.619 1.00 3.39 ? 386 ILE A CG1 1 ATOM 3089 C CG2 . ILE A 1 386 ? 13.896 -12.783 -7.934 1.00 2.00 ? 386 ILE A CG2 1 ATOM 3090 C CD1 . ILE A 1 386 ? 12.662 -11.076 -5.893 1.00 2.00 ? 386 ILE A CD1 1 ATOM 3091 N N . ILE A 1 387 ? 16.751 -13.665 -7.318 1.00 4.10 ? 387 ILE A N 1 ATOM 3092 C CA . ILE A 1 387 ? 17.839 -13.692 -8.271 1.00 5.18 ? 387 ILE A CA 1 ATOM 3093 C C . ILE A 1 387 ? 18.574 -15.001 -8.210 1.00 3.79 ? 387 ILE A C 1 ATOM 3094 O O . ILE A 1 387 ? 18.884 -15.569 -9.251 1.00 4.71 ? 387 ILE A O 1 ATOM 3095 C CB . ILE A 1 387 ? 18.819 -12.511 -8.024 1.00 4.99 ? 387 ILE A CB 1 ATOM 3096 C CG1 . ILE A 1 387 ? 18.215 -11.228 -8.604 1.00 3.99 ? 387 ILE A CG1 1 ATOM 3097 C CG2 . ILE A 1 387 ? 20.179 -12.793 -8.659 1.00 3.19 ? 387 ILE A CG2 1 ATOM 3098 C CD1 . ILE A 1 387 ? 18.616 -9.981 -7.891 1.00 4.49 ? 387 ILE A CD1 1 ATOM 3099 N N . LYS A 1 388 ? 18.821 -15.493 -6.995 1.00 4.01 ? 388 LYS A N 1 ATOM 3100 C CA . LYS A 1 388 ? 19.554 -16.742 -6.817 1.00 3.16 ? 388 LYS A CA 1 ATOM 3101 C C . LYS A 1 388 ? 18.776 -18.018 -6.543 1.00 2.00 ? 388 LYS A C 1 ATOM 3102 O O . LYS A 1 388 ? 19.230 -19.089 -6.908 1.00 2.93 ? 388 LYS A O 1 ATOM 3103 C CB . LYS A 1 388 ? 20.636 -16.569 -5.748 1.00 2.32 ? 388 LYS A CB 1 ATOM 3104 C CG . LYS A 1 388 ? 21.899 -15.946 -6.311 1.00 3.83 ? 388 LYS A CG 1 ATOM 3105 C CD . LYS A 1 388 ? 22.993 -15.819 -5.277 1.00 7.99 ? 388 LYS A CD 1 ATOM 3106 C CE . LYS A 1 388 ? 24.333 -15.477 -5.935 1.00 11.53 ? 388 LYS A CE 1 ATOM 3107 N NZ . LYS A 1 388 ? 24.864 -16.593 -6.800 1.00 14.57 ? 388 LYS A NZ 1 ATOM 3108 N N . ASP A 1 389 ? 17.610 -17.943 -5.923 1.00 2.00 ? 389 ASP A N 1 ATOM 3109 C CA . ASP A 1 389 ? 16.905 -19.186 -5.673 1.00 3.32 ? 389 ASP A CA 1 ATOM 3110 C C . ASP A 1 389 ? 15.617 -19.437 -6.462 1.00 4.42 ? 389 ASP A C 1 ATOM 3111 O O . ASP A 1 389 ? 14.563 -19.635 -5.861 1.00 5.49 ? 389 ASP A O 1 ATOM 3112 C CB . ASP A 1 389 ? 16.629 -19.335 -4.172 1.00 5.05 ? 389 ASP A CB 1 ATOM 3113 C CG . ASP A 1 389 ? 16.012 -20.693 -3.818 1.00 7.73 ? 389 ASP A CG 1 ATOM 3114 O OD1 . ASP A 1 389 ? 16.555 -21.738 -4.243 1.00 7.55 ? 389 ASP A OD1 1 ATOM 3115 O OD2 . ASP A 1 389 ? 14.984 -20.717 -3.105 1.00 8.43 ? 389 ASP A OD2 1 ATOM 3116 N N . GLY A 1 390 ? 15.680 -19.429 -7.796 1.00 3.89 ? 390 GLY A N 1 ATOM 3117 C CA . GLY A 1 390 ? 14.476 -19.725 -8.565 1.00 2.92 ? 390 GLY A CA 1 ATOM 3118 C C . GLY A 1 390 ? 13.890 -18.800 -9.626 1.00 2.80 ? 390 GLY A C 1 ATOM 3119 O O . GLY A 1 390 ? 13.474 -19.270 -10.684 1.00 2.46 ? 390 GLY A O 1 ATOM 3120 N N . GLY A 1 391 ? 13.838 -17.499 -9.356 1.00 3.92 ? 391 GLY A N 1 ATOM 3121 C CA . GLY A 1 391 ? 13.247 -16.564 -10.306 1.00 5.34 ? 391 GLY A CA 1 ATOM 3122 C C . GLY A 1 391 ? 11.957 -16.011 -9.713 1.00 5.36 ? 391 GLY A C 1 ATOM 3123 O O . GLY A 1 391 ? 11.764 -16.140 -8.509 1.00 8.51 ? 391 GLY A O 1 ATOM 3124 N N . ILE A 1 392 ? 11.081 -15.399 -10.516 1.00 4.26 ? 392 ILE A N 1 ATOM 3125 C CA . ILE A 1 392 ? 9.818 -14.856 -9.991 1.00 3.90 ? 392 ILE A CA 1 ATOM 3126 C C . ILE A 1 392 ? 8.685 -15.779 -10.427 1.00 2.28 ? 392 ILE A C 1 ATOM 3127 O O . ILE A 1 392 ? 7.579 -15.736 -9.886 1.00 2.23 ? 392 ILE A O 1 ATOM 3128 C CB . ILE A 1 392 ? 9.518 -13.396 -10.508 1.00 2.01 ? 392 ILE A CB 1 ATOM 3129 C CG1 . ILE A 1 392 ? 8.783 -13.452 -11.861 1.00 2.00 ? 392 ILE A CG1 1 ATOM 3130 C CG2 . ILE A 1 392 ? 10.812 -12.580 -10.559 1.00 2.00 ? 392 ILE A CG2 1 ATOM 3131 C CD1 . ILE A 1 392 ? 8.934 -12.219 -12.744 1.00 2.00 ? 392 ILE A CD1 1 ATOM 3132 N N . ASP A 1 393 ? 8.956 -16.620 -11.415 1.00 2.00 ? 393 ASP A N 1 ATOM 3133 C CA . ASP A 1 393 ? 7.933 -17.548 -11.881 1.00 3.51 ? 393 ASP A CA 1 ATOM 3134 C C . ASP A 1 393 ? 7.351 -18.355 -10.752 1.00 4.62 ? 393 ASP A C 1 ATOM 3135 O O . ASP A 1 393 ? 6.132 -18.407 -10.598 1.00 7.29 ? 393 ASP A O 1 ATOM 3136 C CB . ASP A 1 393 ? 8.477 -18.466 -12.960 1.00 4.68 ? 393 ASP A CB 1 ATOM 3137 C CG . ASP A 1 393 ? 8.298 -17.870 -14.325 1.00 6.13 ? 393 ASP A CG 1 ATOM 3138 O OD1 . ASP A 1 393 ? 8.275 -16.617 -14.382 1.00 6.17 ? 393 ASP A OD1 1 ATOM 3139 O OD2 . ASP A 1 393 ? 8.186 -18.602 -15.332 1.00 5.86 ? 393 ASP A OD2 1 ATOM 3140 N N . PRO A 1 394 ? 8.200 -18.989 -9.933 1.00 4.68 ? 394 PRO A N 1 ATOM 3141 C CA . PRO A 1 394 ? 7.689 -19.784 -8.820 1.00 2.76 ? 394 PRO A CA 1 ATOM 3142 C C . PRO A 1 394 ? 6.820 -18.900 -7.900 1.00 2.50 ? 394 PRO A C 1 ATOM 3143 O O . PRO A 1 394 ? 5.757 -19.318 -7.475 1.00 2.58 ? 394 PRO A O 1 ATOM 3144 C CB . PRO A 1 394 ? 8.975 -20.313 -8.150 1.00 2.13 ? 394 PRO A CB 1 ATOM 3145 C CG . PRO A 1 394 ? 9.971 -20.321 -9.295 1.00 2.94 ? 394 PRO A CG 1 ATOM 3146 C CD . PRO A 1 394 ? 9.668 -18.989 -9.918 1.00 4.04 ? 394 PRO A CD 1 ATOM 3147 N N . LEU A 1 395 ? 7.249 -17.666 -7.640 1.00 2.00 ? 395 LEU A N 1 ATOM 3148 C CA . LEU A 1 395 ? 6.493 -16.768 -6.778 1.00 2.62 ? 395 LEU A CA 1 ATOM 3149 C C . LEU A 1 395 ? 5.123 -16.363 -7.341 1.00 6.23 ? 395 LEU A C 1 ATOM 3150 O O . LEU A 1 395 ? 4.130 -16.358 -6.608 1.00 6.36 ? 395 LEU A O 1 ATOM 3151 C CB . LEU A 1 395 ? 7.334 -15.514 -6.454 1.00 2.43 ? 395 LEU A CB 1 ATOM 3152 C CG . LEU A 1 395 ? 8.703 -15.744 -5.784 1.00 2.00 ? 395 LEU A CG 1 ATOM 3153 C CD1 . LEU A 1 395 ? 9.552 -14.468 -5.756 1.00 2.00 ? 395 LEU A CD1 1 ATOM 3154 C CD2 . LEU A 1 395 ? 8.478 -16.234 -4.369 1.00 2.00 ? 395 LEU A CD2 1 ATOM 3155 N N . VAL A 1 396 ? 5.067 -16.025 -8.629 1.00 3.93 ? 396 VAL A N 1 ATOM 3156 C CA . VAL A 1 396 ? 3.819 -15.613 -9.275 1.00 2.17 ? 396 VAL A CA 1 ATOM 3157 C C . VAL A 1 396 ? 2.818 -16.751 -9.303 1.00 2.00 ? 396 VAL A C 1 ATOM 3158 O O . VAL A 1 396 ? 1.621 -16.524 -9.328 1.00 2.83 ? 396 VAL A O 1 ATOM 3159 C CB . VAL A 1 396 ? 4.063 -15.104 -10.717 1.00 2.00 ? 396 VAL A CB 1 ATOM 3160 C CG1 . VAL A 1 396 ? 2.762 -14.910 -11.432 1.00 2.00 ? 396 VAL A CG1 1 ATOM 3161 C CG2 . VAL A 1 396 ? 4.836 -13.790 -10.678 1.00 2.00 ? 396 VAL A CG2 1 ATOM 3162 N N . ARG A 1 397 ? 3.285 -17.986 -9.294 1.00 2.00 ? 397 ARG A N 1 ATOM 3163 C CA . ARG A 1 397 ? 2.326 -19.070 -9.271 1.00 2.00 ? 397 ARG A CA 1 ATOM 3164 C C . ARG A 1 397 ? 1.846 -19.080 -7.835 1.00 2.00 ? 397 ARG A C 1 ATOM 3165 O O . ARG A 1 397 ? 0.757 -19.542 -7.526 1.00 3.90 ? 397 ARG A O 1 ATOM 3166 C CB . ARG A 1 397 ? 2.975 -20.410 -9.631 1.00 3.76 ? 397 ARG A CB 1 ATOM 3167 C CG . ARG A 1 397 ? 3.583 -20.451 -11.027 1.00 5.79 ? 397 ARG A CG 1 ATOM 3168 C CD . ARG A 1 397 ? 3.668 -21.872 -11.564 1.00 7.12 ? 397 ARG A CD 1 ATOM 3169 N NE . ARG A 1 397 ? 4.433 -21.910 -12.805 1.00 9.60 ? 397 ARG A NE 1 ATOM 3170 C CZ . ARG A 1 397 ? 5.760 -21.972 -12.860 1.00 10.76 ? 397 ARG A CZ 1 ATOM 3171 N NH1 . ARG A 1 397 ? 6.475 -22.012 -11.738 1.00 11.03 ? 397 ARG A NH1 1 ATOM 3172 N NH2 . ARG A 1 397 ? 6.374 -21.983 -14.039 1.00 11.07 ? 397 ARG A NH2 1 ATOM 3173 N N . GLY A 1 398 ? 2.666 -18.536 -6.950 1.00 2.00 ? 398 GLY A N 1 ATOM 3174 C CA . GLY A 1 398 ? 2.283 -18.492 -5.555 1.00 2.00 ? 398 GLY A CA 1 ATOM 3175 C C . GLY A 1 398 ? 1.062 -17.618 -5.373 1.00 2.21 ? 398 GLY A C 1 ATOM 3176 O O . GLY A 1 398 ? 0.018 -18.072 -4.888 1.00 2.30 ? 398 GLY A O 1 ATOM 3177 N N . LEU A 1 399 ? 1.207 -16.358 -5.782 1.00 2.32 ? 399 LEU A N 1 ATOM 3178 C CA . LEU A 1 399 ? 0.151 -15.352 -5.696 1.00 2.00 ? 399 LEU A CA 1 ATOM 3179 C C . LEU A 1 399 ? -1.177 -15.804 -6.329 1.00 2.16 ? 399 LEU A C 1 ATOM 3180 O O . LEU A 1 399 ? -2.242 -15.647 -5.725 1.00 2.00 ? 399 LEU A O 1 ATOM 3181 C CB . LEU A 1 399 ? 0.630 -14.042 -6.344 1.00 2.00 ? 399 LEU A CB 1 ATOM 3182 C CG . LEU A 1 399 ? 1.663 -13.157 -5.630 1.00 2.00 ? 399 LEU A CG 1 ATOM 3183 C CD1 . LEU A 1 399 ? 2.410 -12.315 -6.650 1.00 2.00 ? 399 LEU A CD1 1 ATOM 3184 C CD2 . LEU A 1 399 ? 0.975 -12.266 -4.609 1.00 2.00 ? 399 LEU A CD2 1 ATOM 3185 N N . LEU A 1 400 ? -1.129 -16.376 -7.529 1.00 2.00 ? 400 LEU A N 1 ATOM 3186 C CA . LEU A 1 400 ? -2.359 -16.821 -8.175 1.00 2.00 ? 400 LEU A CA 1 ATOM 3187 C C . LEU A 1 400 ? -3.047 -17.998 -7.479 1.00 2.00 ? 400 LEU A C 1 ATOM 3188 O O . LEU A 1 400 ? -4.274 -18.065 -7.457 1.00 2.00 ? 400 LEU A O 1 ATOM 3189 C CB . LEU A 1 400 ? -2.109 -17.182 -9.647 1.00 2.00 ? 400 LEU A CB 1 ATOM 3190 C CG . LEU A 1 400 ? -1.923 -16.074 -10.694 1.00 2.00 ? 400 LEU A CG 1 ATOM 3191 C CD1 . LEU A 1 400 ? -2.040 -16.680 -12.095 1.00 2.18 ? 400 LEU A CD1 1 ATOM 3192 C CD2 . LEU A 1 400 ? -2.983 -14.990 -10.507 1.00 2.00 ? 400 LEU A CD2 1 ATOM 3193 N N . ALA A 1 401 ? -2.264 -18.904 -6.893 1.00 2.00 ? 401 ALA A N 1 ATOM 3194 C CA . ALA A 1 401 ? -2.815 -20.102 -6.248 1.00 2.00 ? 401 ALA A CA 1 ATOM 3195 C C . ALA A 1 401 ? -3.003 -20.093 -4.734 1.00 3.28 ? 401 ALA A C 1 ATOM 3196 O O . ALA A 1 401 ? -3.794 -20.867 -4.205 1.00 4.70 ? 401 ALA A O 1 ATOM 3197 C CB . ALA A 1 401 ? -1.989 -21.305 -6.629 1.00 2.02 ? 401 ALA A CB 1 ATOM 3198 N N . LYS A 1 402 ? -2.285 -19.245 -4.020 1.00 2.38 ? 402 LYS A N 1 ATOM 3199 C CA . LYS A 1 402 ? -2.460 -19.212 -2.584 1.00 2.00 ? 402 LYS A CA 1 ATOM 3200 C C . LYS A 1 402 ? -3.523 -18.211 -2.172 1.00 2.00 ? 402 LYS A C 1 ATOM 3201 O O . LYS A 1 402 ? -4.033 -17.469 -3.003 1.00 2.00 ? 402 LYS A O 1 ATOM 3202 C CB . LYS A 1 402 ? -1.137 -18.893 -1.920 1.00 2.00 ? 402 LYS A CB 1 ATOM 3203 C CG . LYS A 1 402 ? -0.157 -20.020 -2.052 1.00 2.00 ? 402 LYS A CG 1 ATOM 3204 C CD . LYS A 1 402 ? -0.747 -21.275 -1.461 1.00 2.38 ? 402 LYS A CD 1 ATOM 3205 C CE . LYS A 1 402 ? 0.257 -22.398 -1.469 1.00 2.53 ? 402 LYS A CE 1 ATOM 3206 N NZ . LYS A 1 402 ? -0.328 -23.593 -0.807 1.00 5.39 ? 402 LYS A NZ 1 ATOM 3207 N N . LYS A 1 403 ? -3.853 -18.198 -0.884 1.00 2.00 ? 403 LYS A N 1 ATOM 3208 C CA . LYS A 1 403 ? -4.876 -17.300 -0.344 1.00 2.00 ? 403 LYS A CA 1 ATOM 3209 C C . LYS A 1 403 ? -4.343 -16.260 0.638 1.00 2.00 ? 403 LYS A C 1 ATOM 3210 O O . LYS A 1 403 ? -3.330 -16.477 1.307 1.00 2.00 ? 403 LYS A O 1 ATOM 3211 C CB . LYS A 1 403 ? -5.964 -18.098 0.380 1.00 2.00 ? 403 LYS A CB 1 ATOM 3212 C CG . LYS A 1 403 ? -6.933 -18.884 -0.483 1.00 2.00 ? 403 LYS A CG 1 ATOM 3213 C CD . LYS A 1 403 ? -7.808 -19.766 0.401 1.00 2.70 ? 403 LYS A CD 1 ATOM 3214 C CE . LYS A 1 403 ? -8.732 -20.644 -0.411 1.00 4.17 ? 403 LYS A CE 1 ATOM 3215 N NZ . LYS A 1 403 ? -7.958 -21.412 -1.430 1.00 8.49 ? 403 LYS A NZ 1 ATOM 3216 N N . SER A 1 404 ? -5.064 -15.144 0.729 1.00 2.00 ? 404 SER A N 1 ATOM 3217 C CA . SER A 1 404 ? -4.728 -14.041 1.626 1.00 2.52 ? 404 SER A CA 1 ATOM 3218 C C . SER A 1 404 ? -5.122 -14.422 3.036 1.00 2.49 ? 404 SER A C 1 ATOM 3219 O O . SER A 1 404 ? -5.483 -15.565 3.313 1.00 3.08 ? 404 SER A O 1 ATOM 3220 C CB . SER A 1 404 ? -5.507 -12.777 1.256 1.00 2.83 ? 404 SER A CB 1 ATOM 3221 O OG . SER A 1 404 ? -5.193 -12.312 -0.041 1.00 6.98 ? 404 SER A OG 1 ATOM 3222 N N . LYS A 1 405 ? -5.072 -13.442 3.926 1.00 2.00 ? 405 LYS A N 1 ATOM 3223 C CA . LYS A 1 405 ? -5.436 -13.671 5.307 1.00 2.00 ? 405 LYS A CA 1 ATOM 3224 C C . LYS A 1 405 ? -6.741 -12.952 5.571 1.00 2.45 ? 405 LYS A C 1 ATOM 3225 O O . LYS A 1 405 ? -6.861 -11.754 5.315 1.00 2.60 ? 405 LYS A O 1 ATOM 3226 C CB . LYS A 1 405 ? -4.364 -13.122 6.236 1.00 2.03 ? 405 LYS A CB 1 ATOM 3227 C CG . LYS A 1 405 ? -4.089 -14.036 7.395 1.00 3.56 ? 405 LYS A CG 1 ATOM 3228 C CD . LYS A 1 405 ? -3.698 -13.279 8.636 1.00 2.00 ? 405 LYS A CD 1 ATOM 3229 C CE . LYS A 1 405 ? -4.898 -12.591 9.214 1.00 2.00 ? 405 LYS A CE 1 ATOM 3230 N NZ . LYS A 1 405 ? -4.712 -12.455 10.669 1.00 2.21 ? 405 LYS A NZ 1 ATOM 3231 N N . LEU A 1 406 ? -7.727 -13.677 6.076 1.00 2.00 ? 406 LEU A N 1 ATOM 3232 C CA . LEU A 1 406 ? -9.000 -13.047 6.355 1.00 2.00 ? 406 LEU A CA 1 ATOM 3233 C C . LEU A 1 406 ? -8.882 -12.208 7.611 1.00 3.22 ? 406 LEU A C 1 ATOM 3234 O O . LEU A 1 406 ? -8.234 -12.615 8.578 1.00 2.12 ? 406 LEU A O 1 ATOM 3235 C CB . LEU A 1 406 ? -10.095 -14.095 6.537 1.00 2.00 ? 406 LEU A CB 1 ATOM 3236 C CG . LEU A 1 406 ? -11.469 -13.545 6.909 1.00 2.00 ? 406 LEU A CG 1 ATOM 3237 C CD1 . LEU A 1 406 ? -11.806 -12.360 6.029 1.00 2.98 ? 406 LEU A CD1 1 ATOM 3238 C CD2 . LEU A 1 406 ? -12.495 -14.636 6.749 1.00 2.00 ? 406 LEU A CD2 1 ATOM 3239 N N . MET A 1 407 ? -9.473 -11.019 7.585 1.00 3.71 ? 407 MET A N 1 ATOM 3240 C CA . MET A 1 407 ? -9.453 -10.174 8.760 1.00 2.88 ? 407 MET A CA 1 ATOM 3241 C C . MET A 1 407 ? -10.414 -10.919 9.669 1.00 3.61 ? 407 MET A C 1 ATOM 3242 O O . MET A 1 407 ? -11.485 -11.338 9.231 1.00 4.03 ? 407 MET A O 1 ATOM 3243 C CB . MET A 1 407 ? -9.995 -8.789 8.444 1.00 5.60 ? 407 MET A CB 1 ATOM 3244 C CG . MET A 1 407 ? -9.698 -7.766 9.520 1.00 8.07 ? 407 MET A CG 1 ATOM 3245 S SD . MET A 1 407 ? -10.120 -8.361 11.175 1.00 12.23 ? 407 MET A SD 1 ATOM 3246 C CE . MET A 1 407 ? -11.925 -8.044 11.247 1.00 10.12 ? 407 MET A CE 1 ATOM 3247 N N . ASN A 1 408 ? -10.021 -11.097 10.923 1.00 4.21 ? 408 ASN A N 1 ATOM 3248 C CA . ASN A 1 408 ? -10.823 -11.827 11.899 1.00 3.75 ? 408 ASN A CA 1 ATOM 3249 C C . ASN A 1 408 ? -10.724 -11.123 13.256 1.00 4.19 ? 408 ASN A C 1 ATOM 3250 O O . ASN A 1 408 ? -9.675 -11.164 13.894 1.00 3.69 ? 408 ASN A O 1 ATOM 3251 C CB . ASN A 1 408 ? -10.272 -13.254 11.993 1.00 6.28 ? 408 ASN A CB 1 ATOM 3252 C CG . ASN A 1 408 ? -11.185 -14.198 12.746 1.00 9.55 ? 408 ASN A CG 1 ATOM 3253 O OD1 . ASN A 1 408 ? -11.360 -14.087 13.967 1.00 10.65 ? 408 ASN A OD1 1 ATOM 3254 N ND2 . ASN A 1 408 ? -11.771 -15.146 12.018 1.00 10.00 ? 408 ASN A ND2 1 ATOM 3255 N N . GLN A 1 409 ? -11.807 -10.475 13.684 1.00 3.53 ? 409 GLN A N 1 ATOM 3256 C CA . GLN A 1 409 ? -11.850 -9.745 14.961 1.00 4.15 ? 409 GLN A CA 1 ATOM 3257 C C . GLN A 1 409 ? -11.019 -10.324 16.090 1.00 4.97 ? 409 GLN A C 1 ATOM 3258 O O . GLN A 1 409 ? -10.729 -9.644 17.068 1.00 3.20 ? 409 GLN A O 1 ATOM 3259 C CB . GLN A 1 409 ? -13.288 -9.645 15.467 1.00 4.67 ? 409 GLN A CB 1 ATOM 3260 C CG . GLN A 1 409 ? -13.987 -8.373 15.076 1.00 8.54 ? 409 GLN A CG 1 ATOM 3261 C CD . GLN A 1 409 ? -15.461 -8.385 15.418 1.00 9.94 ? 409 GLN A CD 1 ATOM 3262 O OE1 . GLN A 1 409 ? -16.220 -9.231 14.933 1.00 11.72 ? 409 GLN A OE1 1 ATOM 3263 N NE2 . GLN A 1 409 ? -15.879 -7.442 16.253 1.00 12.11 ? 409 GLN A NE2 1 ATOM 3264 N N . ASN A 1 410 ? -10.542 -11.551 15.942 1.00 6.80 ? 410 ASN A N 1 ATOM 3265 C CA . ASN A 1 410 ? -9.745 -12.319 16.967 1.00 8.25 ? 410 ASN A CA 1 ATOM 3266 C C . ASN A 1 410 ? -8.229 -12.558 16.682 1.00 7.87 ? 410 ASN A C 1 ATOM 3267 O O . ASN A 1 410 ? -7.440 -12.645 17.610 1.00 6.83 ? 410 ASN A O 1 ATOM 3268 C CB . ASN A 1 410 ? -10.536 -13.596 17.183 1.00 12.44 ? 410 ASN A CB 1 ATOM 3269 C CG . ASN A 1 410 ? -10.233 -14.211 18.518 1.00 16.58 ? 410 ASN A CG 1 ATOM 3270 O OD1 . ASN A 1 410 ? -9.091 -14.557 18.795 1.00 18.01 ? 410 ASN A OD1 1 ATOM 3271 N ND2 . ASN A 1 410 ? -11.263 -14.358 19.354 1.00 17.95 ? 410 ASN A ND2 1 ATOM 3272 N N . LYS A 1 411 ? -7.870 -12.679 15.429 1.00 7.53 ? 411 LYS A N 1 ATOM 3273 C CA . LYS A 1 411 ? -6.523 -12.816 14.955 1.00 4.24 ? 411 LYS A CA 1 ATOM 3274 C C . LYS A 1 411 ? -6.335 -11.610 14.049 1.00 2.32 ? 411 LYS A C 1 ATOM 3275 O O . LYS A 1 411 ? -6.757 -11.621 12.902 1.00 2.00 ? 411 LYS A O 1 ATOM 3276 C CB . LYS A 1 411 ? -6.289 -14.172 14.268 1.00 2.97 ? 411 LYS A CB 1 ATOM 3277 C CG . LYS A 1 411 ? -6.703 -15.390 15.104 1.00 2.59 ? 411 LYS A CG 1 ATOM 3278 C CD . LYS A 1 411 ? -6.553 -16.654 14.271 1.00 3.70 ? 411 LYS A CD 1 ATOM 3279 C CE . LYS A 1 411 ? -6.884 -17.906 15.078 1.00 2.85 ? 411 LYS A CE 1 ATOM 3280 N NZ . LYS A 1 411 ? -8.350 -18.192 15.075 1.00 3.33 ? 411 LYS A NZ 1 ATOM 3281 N N . MET A 1 412 ? -5.687 -10.577 14.554 1.00 2.50 ? 412 MET A N 1 ATOM 3282 C CA . MET A 1 412 ? -5.575 -9.404 13.733 1.00 2.97 ? 412 MET A CA 1 ATOM 3283 C C . MET A 1 412 ? -4.334 -9.382 12.808 1.00 4.09 ? 412 MET A C 1 ATOM 3284 O O . MET A 1 412 ? -4.451 -9.375 11.578 1.00 3.17 ? 412 MET A O 1 ATOM 3285 C CB . MET A 1 412 ? -5.671 -8.161 14.603 1.00 2.14 ? 412 MET A CB 1 ATOM 3286 C CG . MET A 1 412 ? -7.086 -7.572 14.648 1.00 2.00 ? 412 MET A CG 1 ATOM 3287 S SD . MET A 1 412 ? -7.384 -6.476 16.053 1.00 2.46 ? 412 MET A SD 1 ATOM 3288 C CE . MET A 1 412 ? -9.068 -6.914 16.460 1.00 2.00 ? 412 MET A CE 1 ATOM 3289 N N . VAL A 1 413 ? -3.160 -9.375 13.431 1.00 4.62 ? 413 VAL A N 1 ATOM 3290 C CA . VAL A 1 413 ? -1.914 -9.313 12.671 1.00 3.03 ? 413 VAL A CA 1 ATOM 3291 C C . VAL A 1 413 ? -0.914 -10.441 12.983 1.00 4.31 ? 413 VAL A C 1 ATOM 3292 O O . VAL A 1 413 ? -0.580 -10.670 14.147 1.00 6.79 ? 413 VAL A O 1 ATOM 3293 C CB . VAL A 1 413 ? -1.231 -7.946 12.909 1.00 2.00 ? 413 VAL A CB 1 ATOM 3294 C CG1 . VAL A 1 413 ? 0.126 -7.926 12.269 1.00 2.00 ? 413 VAL A CG1 1 ATOM 3295 C CG2 . VAL A 1 413 ? -2.115 -6.829 12.366 1.00 2.00 ? 413 VAL A CG2 1 ATOM 3296 N N . THR A 1 414 ? -0.440 -11.126 11.936 1.00 4.54 ? 414 THR A N 1 ATOM 3297 C CA . THR A 1 414 ? 0.539 -12.227 12.038 1.00 3.32 ? 414 THR A CA 1 ATOM 3298 C C . THR A 1 414 ? 1.702 -11.877 12.929 1.00 2.00 ? 414 THR A C 1 ATOM 3299 O O . THR A 1 414 ? 2.146 -10.731 12.975 1.00 2.00 ? 414 THR A O 1 ATOM 3300 C CB . THR A 1 414 ? 1.227 -12.551 10.720 1.00 3.13 ? 414 THR A CB 1 ATOM 3301 O OG1 . THR A 1 414 ? 0.321 -12.375 9.627 1.00 5.29 ? 414 THR A OG1 1 ATOM 3302 C CG2 . THR A 1 414 ? 1.757 -13.971 10.759 1.00 2.00 ? 414 THR A CG2 1 ATOM 3303 N N . SER A 1 415 ? 2.242 -12.891 13.582 1.00 2.00 ? 415 SER A N 1 ATOM 3304 C CA . SER A 1 415 ? 3.359 -12.693 14.481 1.00 2.00 ? 415 SER A CA 1 ATOM 3305 C C . SER A 1 415 ? 4.624 -12.425 13.702 1.00 2.00 ? 415 SER A C 1 ATOM 3306 O O . SER A 1 415 ? 5.610 -11.938 14.246 1.00 2.00 ? 415 SER A O 1 ATOM 3307 C CB . SER A 1 415 ? 3.522 -13.922 15.351 1.00 2.75 ? 415 SER A CB 1 ATOM 3308 O OG . SER A 1 415 ? 2.266 -14.247 15.922 1.00 3.84 ? 415 SER A OG 1 ATOM 3309 N N . GLU A 1 416 ? 4.592 -12.781 12.419 1.00 2.00 ? 416 GLU A N 1 ATOM 3310 C CA . GLU A 1 416 ? 5.746 -12.512 11.575 1.00 2.00 ? 416 GLU A CA 1 ATOM 3311 C C . GLU A 1 416 ? 5.832 -11.004 11.380 1.00 2.00 ? 416 GLU A C 1 ATOM 3312 O O . GLU A 1 416 ? 6.871 -10.491 10.987 1.00 2.09 ? 416 GLU A O 1 ATOM 3313 C CB . GLU A 1 416 ? 5.661 -13.258 10.219 1.00 2.70 ? 416 GLU A CB 1 ATOM 3314 C CG . GLU A 1 416 ? 5.366 -14.761 10.335 1.00 3.43 ? 416 GLU A CG 1 ATOM 3315 C CD . GLU A 1 416 ? 6.469 -15.590 11.018 1.00 3.58 ? 416 GLU A CD 1 ATOM 3316 O OE1 . GLU A 1 416 ? 6.131 -16.679 11.523 1.00 2.00 ? 416 GLU A OE1 1 ATOM 3317 O OE2 . GLU A 1 416 ? 7.646 -15.161 11.031 1.00 3.15 ? 416 GLU A OE2 1 ATOM 3318 N N . LEU A 1 417 ? 4.738 -10.298 11.670 1.00 2.00 ? 417 LEU A N 1 ATOM 3319 C CA . LEU A 1 417 ? 4.700 -8.838 11.537 1.00 2.00 ? 417 LEU A CA 1 ATOM 3320 C C . LEU A 1 417 ? 4.610 -8.113 12.870 1.00 2.11 ? 417 LEU A C 1 ATOM 3321 O O . LEU A 1 417 ? 5.056 -6.974 12.996 1.00 2.00 ? 417 LEU A O 1 ATOM 3322 C CB . LEU A 1 417 ? 3.525 -8.394 10.666 1.00 2.00 ? 417 LEU A CB 1 ATOM 3323 C CG . LEU A 1 417 ? 3.820 -8.270 9.175 1.00 2.00 ? 417 LEU A CG 1 ATOM 3324 C CD1 . LEU A 1 417 ? 2.597 -7.768 8.437 1.00 2.00 ? 417 LEU A CD1 1 ATOM 3325 C CD2 . LEU A 1 417 ? 4.979 -7.323 8.986 1.00 2.00 ? 417 LEU A CD2 1 ATOM 3326 N N . ARG A 1 418 ? 4.025 -8.766 13.865 1.00 4.02 ? 418 ARG A N 1 ATOM 3327 C CA . ARG A 1 418 ? 3.890 -8.155 15.179 1.00 2.78 ? 418 ARG A CA 1 ATOM 3328 C C . ARG A 1 418 ? 5.189 -8.211 15.998 1.00 3.11 ? 418 ARG A C 1 ATOM 3329 O O . ARG A 1 418 ? 5.565 -7.222 16.619 1.00 2.59 ? 418 ARG A O 1 ATOM 3330 C CB . ARG A 1 418 ? 2.755 -8.828 15.951 1.00 3.77 ? 418 ARG A CB 1 ATOM 3331 C CG . ARG A 1 418 ? 2.178 -7.963 17.044 1.00 6.63 ? 418 ARG A CG 1 ATOM 3332 C CD . ARG A 1 418 ? 0.925 -8.590 17.610 1.00 9.22 ? 418 ARG A CD 1 ATOM 3333 N NE . ARG A 1 418 ? 1.264 -9.731 18.445 1.00 13.73 ? 418 ARG A NE 1 ATOM 3334 C CZ . ARG A 1 418 ? 1.870 -9.620 19.622 1.00 14.59 ? 418 ARG A CZ 1 ATOM 3335 N NH1 . ARG A 1 418 ? 2.181 -8.414 20.081 1.00 16.16 ? 418 ARG A NH1 1 ATOM 3336 N NH2 . ARG A 1 418 ? 2.184 -10.706 20.326 1.00 14.83 ? 418 ARG A NH2 1 ATOM 3337 N N . ASN A 1 419 ? 5.885 -9.350 15.977 1.00 2.95 ? 419 ASN A N 1 ATOM 3338 C CA . ASN A 1 419 ? 7.123 -9.519 16.743 1.00 2.00 ? 419 ASN A CA 1 ATOM 3339 C C . ASN A 1 419 ? 8.435 -9.551 15.975 1.00 2.26 ? 419 ASN A C 1 ATOM 3340 O O . ASN A 1 419 ? 9.465 -9.090 16.480 1.00 2.00 ? 419 ASN A O 1 ATOM 3341 C CB . ASN A 1 419 ? 7.056 -10.803 17.545 1.00 3.34 ? 419 ASN A CB 1 ATOM 3342 C CG . ASN A 1 419 ? 5.939 -10.801 18.538 1.00 5.71 ? 419 ASN A CG 1 ATOM 3343 O OD1 . ASN A 1 419 ? 5.823 -9.881 19.359 1.00 5.46 ? 419 ASN A OD1 1 ATOM 3344 N ND2 . ASN A 1 419 ? 5.099 -11.838 18.484 1.00 6.56 ? 419 ASN A ND2 1 ATOM 3345 N N . LYS A 1 420 ? 8.392 -10.114 14.768 1.00 2.80 ? 420 LYS A N 1 ATOM 3346 C CA . LYS A 1 420 ? 9.570 -10.281 13.923 1.00 2.00 ? 420 LYS A CA 1 ATOM 3347 C C . LYS A 1 420 ? 9.656 -9.378 12.688 1.00 2.00 ? 420 LYS A C 1 ATOM 3348 O O . LYS A 1 420 ? 10.076 -9.842 11.635 1.00 3.08 ? 420 LYS A O 1 ATOM 3349 C CB . LYS A 1 420 ? 9.636 -11.733 13.455 1.00 2.00 ? 420 LYS A CB 1 ATOM 3350 C CG . LYS A 1 420 ? 8.842 -12.708 14.304 1.00 2.00 ? 420 LYS A CG 1 ATOM 3351 C CD . LYS A 1 420 ? 9.747 -13.599 15.127 1.00 2.00 ? 420 LYS A CD 1 ATOM 3352 C CE . LYS A 1 420 ? 9.688 -15.031 14.604 1.00 2.81 ? 420 LYS A CE 1 ATOM 3353 N NZ . LYS A 1 420 ? 10.698 -15.944 15.241 1.00 5.39 ? 420 LYS A NZ 1 ATOM 3354 N N . LEU A 1 421 ? 9.278 -8.105 12.791 1.00 3.32 ? 421 LEU A N 1 ATOM 3355 C CA . LEU A 1 421 ? 9.348 -7.211 11.622 1.00 3.88 ? 421 LEU A CA 1 ATOM 3356 C C . LEU A 1 421 ? 10.726 -6.617 11.409 1.00 3.44 ? 421 LEU A C 1 ATOM 3357 O O . LEU A 1 421 ? 11.323 -6.093 12.342 1.00 4.70 ? 421 LEU A O 1 ATOM 3358 C CB . LEU A 1 421 ? 8.354 -6.045 11.735 1.00 2.23 ? 421 LEU A CB 1 ATOM 3359 C CG . LEU A 1 421 ? 8.594 -4.934 10.698 1.00 2.00 ? 421 LEU A CG 1 ATOM 3360 C CD1 . LEU A 1 421 ? 8.349 -5.481 9.314 1.00 2.00 ? 421 LEU A CD1 1 ATOM 3361 C CD2 . LEU A 1 421 ? 7.697 -3.737 10.960 1.00 2.96 ? 421 LEU A CD2 1 ATOM 3362 N N . PHE A 1 422 ? 11.226 -6.675 10.180 1.00 3.21 ? 422 PHE A N 1 ATOM 3363 C CA . PHE A 1 422 ? 12.531 -6.091 9.905 1.00 4.10 ? 422 PHE A CA 1 ATOM 3364 C C . PHE A 1 422 ? 12.434 -4.659 9.374 1.00 5.82 ? 422 PHE A C 1 ATOM 3365 O O . PHE A 1 422 ? 11.617 -4.360 8.491 1.00 7.36 ? 422 PHE A O 1 ATOM 3366 C CB . PHE A 1 422 ? 13.295 -6.919 8.880 1.00 3.76 ? 422 PHE A CB 1 ATOM 3367 C CG . PHE A 1 422 ? 14.758 -6.559 8.782 1.00 3.22 ? 422 PHE A CG 1 ATOM 3368 C CD1 . PHE A 1 422 ? 15.594 -6.719 9.874 1.00 2.08 ? 422 PHE A CD1 1 ATOM 3369 C CD2 . PHE A 1 422 ? 15.301 -6.091 7.599 1.00 2.55 ? 422 PHE A CD2 1 ATOM 3370 C CE1 . PHE A 1 422 ? 16.937 -6.426 9.785 1.00 2.00 ? 422 PHE A CE1 1 ATOM 3371 C CE2 . PHE A 1 422 ? 16.656 -5.795 7.510 1.00 2.00 ? 422 PHE A CE2 1 ATOM 3372 C CZ . PHE A 1 422 ? 17.469 -5.964 8.603 1.00 2.00 ? 422 PHE A CZ 1 ATOM 3373 N N . GLN A 1 423 ? 13.269 -3.775 9.913 1.00 4.60 ? 423 GLN A N 1 ATOM 3374 C CA . GLN A 1 423 ? 13.298 -2.394 9.448 1.00 5.36 ? 423 GLN A CA 1 ATOM 3375 C C . GLN A 1 423 ? 14.640 -2.231 8.742 1.00 5.60 ? 423 GLN A C 1 ATOM 3376 O O . GLN A 1 423 ? 15.654 -2.760 9.207 1.00 6.58 ? 423 GLN A O 1 ATOM 3377 C CB . GLN A 1 423 ? 13.164 -1.422 10.624 1.00 4.57 ? 423 GLN A CB 1 ATOM 3378 C CG . GLN A 1 423 ? 11.778 -1.423 11.252 1.00 5.20 ? 423 GLN A CG 1 ATOM 3379 C CD . GLN A 1 423 ? 10.740 -0.676 10.429 1.00 6.50 ? 423 GLN A CD 1 ATOM 3380 O OE1 . GLN A 1 423 ? 10.659 -0.825 9.205 1.00 8.40 ? 423 GLN A OE1 1 ATOM 3381 N NE2 . GLN A 1 423 ? 9.927 0.126 11.108 1.00 7.67 ? 423 GLN A NE2 1 ATOM 3382 N N . PRO A 1 424 ? 14.665 -1.512 7.602 1.00 4.91 ? 424 PRO A N 1 ATOM 3383 C CA . PRO A 1 424 ? 15.917 -1.319 6.857 1.00 4.61 ? 424 PRO A CA 1 ATOM 3384 C C . PRO A 1 424 ? 17.013 -0.625 7.659 1.00 4.60 ? 424 PRO A C 1 ATOM 3385 O O . PRO A 1 424 ? 18.176 -1.015 7.620 1.00 3.91 ? 424 PRO A O 1 ATOM 3386 C CB . PRO A 1 424 ? 15.468 -0.524 5.629 1.00 3.44 ? 424 PRO A CB 1 ATOM 3387 C CG . PRO A 1 424 ? 14.306 0.271 6.142 1.00 3.78 ? 424 PRO A CG 1 ATOM 3388 C CD . PRO A 1 424 ? 13.567 -0.723 7.008 1.00 4.63 ? 424 PRO A CD 1 ATOM 3389 N N . THR A 1 425 ? 16.626 0.397 8.399 1.00 5.52 ? 425 THR A N 1 ATOM 3390 C CA . THR A 1 425 ? 17.559 1.149 9.216 1.00 9.38 ? 425 THR A CA 1 ATOM 3391 C C . THR A 1 425 ? 18.415 0.254 10.115 1.00 10.50 ? 425 THR A C 1 ATOM 3392 O O . THR A 1 425 ? 19.641 0.207 10.003 1.00 10.21 ? 425 THR A O 1 ATOM 3393 C CB . THR A 1 425 ? 16.799 2.114 10.150 1.00 10.54 ? 425 THR A CB 1 ATOM 3394 O OG1 . THR A 1 425 ? 15.730 2.740 9.428 1.00 13.44 ? 425 THR A OG1 1 ATOM 3395 C CG2 . THR A 1 425 ? 17.745 3.172 10.688 1.00 10.85 ? 425 THR A CG2 1 ATOM 3396 N N . HIS A 1 426 ? 17.768 -0.468 10.998 1.00 11.42 ? 426 HIS A N 1 ATOM 3397 C CA . HIS A 1 426 ? 18.409 -1.305 12.000 1.00 11.68 ? 426 HIS A CA 1 ATOM 3398 C C . HIS A 1 426 ? 18.675 -2.742 11.665 1.00 12.00 ? 426 HIS A C 1 ATOM 3399 O O . HIS A 1 426 ? 18.321 -3.233 10.606 1.00 11.91 ? 426 HIS A O 1 ATOM 3400 C CB . HIS A 1 426 ? 17.517 -1.358 13.250 1.00 11.80 ? 426 HIS A CB 1 ATOM 3401 C CG . HIS A 1 426 ? 16.935 0.009 13.579 1.00 11.97 ? 426 HIS A CG 1 ATOM 3402 N ND1 . HIS A 1 426 ? 17.322 0.723 14.700 1.00 11.76 ? 426 HIS A ND1 1 ATOM 3403 C CD2 . HIS A 1 426 ? 16.044 0.774 12.936 1.00 11.75 ? 426 HIS A CD2 1 ATOM 3404 C CE1 . HIS A 1 426 ? 16.715 1.880 14.729 1.00 12.52 ? 426 HIS A CE1 1 ATOM 3405 N NE2 . HIS A 1 426 ? 15.936 1.931 13.669 1.00 11.94 ? 426 HIS A NE2 1 ATOM 3406 N N . LYS A 1 427 ? 19.327 -3.419 12.652 1.00 13.13 ? 427 LYS A N 1 ATOM 3407 C CA . LYS A 1 427 ? 19.832 -4.797 12.546 1.00 12.75 ? 427 LYS A CA 1 ATOM 3408 C C . LYS A 1 427 ? 18.910 -5.979 12.902 1.00 11.02 ? 427 LYS A C 1 ATOM 3409 O O . LYS A 1 427 ? 18.645 -6.845 12.066 1.00 12.12 ? 427 LYS A O 1 ATOM 3410 C CB . LYS A 1 427 ? 21.117 -4.897 13.392 1.00 14.51 ? 427 LYS A CB 1 ATOM 3411 C CG . LYS A 1 427 ? 22.269 -4.028 12.921 1.00 17.32 ? 427 LYS A CG 1 ATOM 3412 C CD . LYS A 1 427 ? 23.456 -4.093 13.864 1.00 18.91 ? 427 LYS A CD 1 ATOM 3413 C CE . LYS A 1 427 ? 24.501 -3.032 13.542 1.00 19.36 ? 427 LYS A CE 1 ATOM 3414 N NZ . LYS A 1 427 ? 23.898 -1.664 13.475 1.00 19.90 ? 427 LYS A NZ 1 ATOM 3415 N N . ILE A 1 428 ? 18.420 -6.035 14.134 1.00 9.54 ? 428 ILE A N 1 ATOM 3416 C CA . ILE A 1 428 ? 17.610 -7.183 14.530 1.00 9.09 ? 428 ILE A CA 1 ATOM 3417 C C . ILE A 1 428 ? 16.277 -7.291 13.793 1.00 7.46 ? 428 ILE A C 1 ATOM 3418 O O . ILE A 1 428 ? 15.809 -6.356 13.155 1.00 7.14 ? 428 ILE A O 1 ATOM 3419 C CB . ILE A 1 428 ? 17.389 -7.225 16.055 1.00 9.62 ? 428 ILE A CB 1 ATOM 3420 C CG1 . ILE A 1 428 ? 16.129 -6.459 16.462 1.00 9.47 ? 428 ILE A CG1 1 ATOM 3421 C CG2 . ILE A 1 428 ? 18.609 -6.657 16.768 1.00 9.77 ? 428 ILE A CG2 1 ATOM 3422 C CD1 . ILE A 1 428 ? 16.220 -4.970 16.226 1.00 11.45 ? 428 ILE A CD1 1 ATOM 3423 N N . HIS A 1 429 ? 15.662 -8.464 13.907 1.00 7.46 ? 429 HIS A N 1 ATOM 3424 C CA . HIS A 1 429 ? 14.377 -8.794 13.279 1.00 7.60 ? 429 HIS A CA 1 ATOM 3425 C C . HIS A 1 429 ? 13.248 -8.789 14.325 1.00 8.95 ? 429 HIS A C 1 ATOM 3426 O O . HIS A 1 429 ? 12.413 -9.705 14.327 1.00 9.56 ? 429 HIS A O 1 ATOM 3427 C CB . HIS A 1 429 ? 14.436 -10.217 12.699 1.00 6.23 ? 429 HIS A CB 1 ATOM 3428 C CG . HIS A 1 429 ? 14.815 -10.294 11.254 1.00 4.24 ? 429 HIS A CG 1 ATOM 3429 N ND1 . HIS A 1 429 ? 16.042 -9.885 10.777 1.00 3.17 ? 429 HIS A ND1 1 ATOM 3430 C CD2 . HIS A 1 429 ? 14.128 -10.761 10.183 1.00 2.61 ? 429 HIS A CD2 1 ATOM 3431 C CE1 . HIS A 1 429 ? 16.091 -10.093 9.473 1.00 4.36 ? 429 HIS A CE1 1 ATOM 3432 N NE2 . HIS A 1 429 ? 14.942 -10.623 9.088 1.00 2.75 ? 429 HIS A NE2 1 ATOM 3433 N N . GLY A 1 430 ? 13.194 -7.789 15.203 1.00 7.88 ? 430 GLY A N 1 ATOM 3434 C CA . GLY A 1 430 ? 12.160 -7.823 16.226 1.00 6.44 ? 430 GLY A CA 1 ATOM 3435 C C . GLY A 1 430 ? 11.275 -6.618 16.453 1.00 5.90 ? 430 GLY A C 1 ATOM 3436 O O . GLY A 1 430 ? 10.989 -6.271 17.596 1.00 6.18 ? 430 GLY A O 1 ATOM 3437 N N . PHE A 1 431 ? 10.820 -5.983 15.383 1.00 5.05 ? 431 PHE A N 1 ATOM 3438 C CA . PHE A 1 431 ? 9.956 -4.830 15.541 1.00 4.66 ? 431 PHE A CA 1 ATOM 3439 C C . PHE A 1 431 ? 8.486 -5.213 15.521 1.00 5.64 ? 431 PHE A C 1 ATOM 3440 O O . PHE A 1 431 ? 8.150 -6.395 15.444 1.00 5.38 ? 431 PHE A O 1 ATOM 3441 C CB . PHE A 1 431 ? 10.252 -3.803 14.460 1.00 3.25 ? 431 PHE A CB 1 ATOM 3442 C CG . PHE A 1 431 ? 11.366 -2.871 14.817 1.00 2.65 ? 431 PHE A CG 1 ATOM 3443 C CD1 . PHE A 1 431 ? 12.646 -3.049 14.307 1.00 2.00 ? 431 PHE A CD1 1 ATOM 3444 C CD2 . PHE A 1 431 ? 11.131 -1.810 15.679 1.00 2.97 ? 431 PHE A CD2 1 ATOM 3445 C CE1 . PHE A 1 431 ? 13.676 -2.182 14.648 1.00 2.00 ? 431 PHE A CE1 1 ATOM 3446 C CE2 . PHE A 1 431 ? 12.150 -0.937 16.029 1.00 3.78 ? 431 PHE A CE2 1 ATOM 3447 C CZ . PHE A 1 431 ? 13.427 -1.122 15.512 1.00 3.58 ? 431 PHE A CZ 1 ATOM 3448 N N . ASP A 1 432 ? 7.608 -4.217 15.604 1.00 7.05 ? 432 ASP A N 1 ATOM 3449 C CA . ASP A 1 432 ? 6.171 -4.482 15.596 1.00 6.61 ? 432 ASP A CA 1 ATOM 3450 C C . ASP A 1 432 ? 5.333 -3.527 14.746 1.00 5.39 ? 432 ASP A C 1 ATOM 3451 O O . ASP A 1 432 ? 4.990 -2.430 15.192 1.00 5.30 ? 432 ASP A O 1 ATOM 3452 C CB . ASP A 1 432 ? 5.620 -4.462 17.017 1.00 7.63 ? 432 ASP A CB 1 ATOM 3453 C CG . ASP A 1 432 ? 4.114 -4.647 17.048 1.00 9.69 ? 432 ASP A CG 1 ATOM 3454 O OD1 . ASP A 1 432 ? 3.508 -4.762 15.955 1.00 8.73 ? 432 ASP A OD1 1 ATOM 3455 O OD2 . ASP A 1 432 ? 3.535 -4.677 18.160 1.00 11.92 ? 432 ASP A OD2 1 ATOM 3456 N N . LEU A 1 433 ? 4.965 -3.968 13.546 1.00 4.52 ? 433 LEU A N 1 ATOM 3457 C CA . LEU A 1 433 ? 4.163 -3.144 12.649 1.00 4.38 ? 433 LEU A CA 1 ATOM 3458 C C . LEU A 1 433 ? 2.931 -2.586 13.345 1.00 2.00 ? 433 LEU A C 1 ATOM 3459 O O . LEU A 1 433 ? 2.626 -1.406 13.209 1.00 2.00 ? 433 LEU A O 1 ATOM 3460 C CB . LEU A 1 433 ? 3.735 -3.939 11.412 1.00 2.25 ? 433 LEU A CB 1 ATOM 3461 C CG . LEU A 1 433 ? 2.963 -3.112 10.386 1.00 2.00 ? 433 LEU A CG 1 ATOM 3462 C CD1 . LEU A 1 433 ? 3.658 -1.773 10.166 1.00 2.00 ? 433 LEU A CD1 1 ATOM 3463 C CD2 . LEU A 1 433 ? 2.859 -3.895 9.097 1.00 2.00 ? 433 LEU A CD2 1 ATOM 3464 N N . ALA A 1 434 ? 2.230 -3.434 14.092 1.00 2.00 ? 434 ALA A N 1 ATOM 3465 C CA . ALA A 1 434 ? 1.035 -3.000 14.805 1.00 2.69 ? 434 ALA A CA 1 ATOM 3466 C C . ALA A 1 434 ? 1.361 -1.809 15.707 1.00 5.02 ? 434 ALA A C 1 ATOM 3467 O O . ALA A 1 434 ? 0.717 -0.758 15.618 1.00 6.01 ? 434 ALA A O 1 ATOM 3468 C CB . ALA A 1 434 ? 0.464 -4.147 15.634 1.00 2.00 ? 434 ALA A CB 1 ATOM 3469 N N . ALA A 1 435 ? 2.362 -1.963 16.569 1.00 2.76 ? 435 ALA A N 1 ATOM 3470 C CA . ALA A 1 435 ? 2.745 -0.879 17.464 1.00 2.21 ? 435 ALA A CA 1 ATOM 3471 C C . ALA A 1 435 ? 3.233 0.329 16.683 1.00 2.83 ? 435 ALA A C 1 ATOM 3472 O O . ALA A 1 435 ? 2.992 1.459 17.084 1.00 4.06 ? 435 ALA A O 1 ATOM 3473 C CB . ALA A 1 435 ? 3.818 -1.339 18.429 1.00 2.54 ? 435 ALA A CB 1 ATOM 3474 N N . ILE A 1 436 ? 3.933 0.111 15.576 1.00 2.00 ? 436 ILE A N 1 ATOM 3475 C CA . ILE A 1 436 ? 4.381 1.255 14.803 1.00 2.00 ? 436 ILE A CA 1 ATOM 3476 C C . ILE A 1 436 ? 3.115 2.025 14.420 1.00 2.00 ? 436 ILE A C 1 ATOM 3477 O O . ILE A 1 436 ? 3.010 3.224 14.644 1.00 2.89 ? 436 ILE A O 1 ATOM 3478 C CB . ILE A 1 436 ? 5.058 0.860 13.489 1.00 2.00 ? 436 ILE A CB 1 ATOM 3479 C CG1 . ILE A 1 436 ? 5.948 -0.371 13.673 1.00 2.63 ? 436 ILE A CG1 1 ATOM 3480 C CG2 . ILE A 1 436 ? 5.849 2.045 12.970 1.00 2.00 ? 436 ILE A CG2 1 ATOM 3481 C CD1 . ILE A 1 436 ? 7.327 -0.089 14.203 1.00 3.69 ? 436 ILE A CD1 1 ATOM 3482 N N . ASN A 1 437 ? 2.146 1.314 13.851 1.00 2.08 ? 437 ASN A N 1 ATOM 3483 C CA . ASN A 1 437 ? 0.894 1.921 13.408 1.00 2.39 ? 437 ASN A CA 1 ATOM 3484 C C . ASN A 1 437 ? 0.203 2.774 14.451 1.00 2.00 ? 437 ASN A C 1 ATOM 3485 O O . ASN A 1 437 ? -0.155 3.921 14.196 1.00 2.00 ? 437 ASN A O 1 ATOM 3486 C CB . ASN A 1 437 ? -0.083 0.845 12.944 1.00 3.39 ? 437 ASN A CB 1 ATOM 3487 C CG . ASN A 1 437 ? 0.442 0.051 11.780 1.00 4.07 ? 437 ASN A CG 1 ATOM 3488 O OD1 . ASN A 1 437 ? 0.819 0.607 10.743 1.00 2.00 ? 437 ASN A OD1 1 ATOM 3489 N ND2 . ASN A 1 437 ? 0.468 -1.266 11.939 1.00 6.87 ? 437 ASN A ND2 1 ATOM 3490 N N . LEU A 1 438 ? -0.016 2.200 15.621 1.00 2.00 ? 438 LEU A N 1 ATOM 3491 C CA . LEU A 1 438 ? -0.674 2.938 16.669 1.00 2.10 ? 438 LEU A CA 1 ATOM 3492 C C . LEU A 1 438 ? 0.173 4.142 17.053 1.00 2.00 ? 438 LEU A C 1 ATOM 3493 O O . LEU A 1 438 ? -0.331 5.257 17.115 1.00 3.62 ? 438 LEU A O 1 ATOM 3494 C CB . LEU A 1 438 ? -0.930 2.034 17.880 1.00 3.23 ? 438 LEU A CB 1 ATOM 3495 C CG . LEU A 1 438 ? -2.015 0.961 17.678 1.00 4.78 ? 438 LEU A CG 1 ATOM 3496 C CD1 . LEU A 1 438 ? -2.181 0.170 18.968 1.00 3.16 ? 438 LEU A CD1 1 ATOM 3497 C CD2 . LEU A 1 438 ? -3.350 1.608 17.267 1.00 3.10 ? 438 LEU A CD2 1 ATOM 3498 N N . GLN A 1 439 ? 1.461 3.939 17.295 1.00 2.07 ? 439 GLN A N 1 ATOM 3499 C CA . GLN A 1 439 ? 2.310 5.063 17.666 1.00 2.48 ? 439 GLN A CA 1 ATOM 3500 C C . GLN A 1 439 ? 2.168 6.119 16.574 1.00 2.00 ? 439 GLN A C 1 ATOM 3501 O O . GLN A 1 439 ? 1.866 7.283 16.842 1.00 3.17 ? 439 GLN A O 1 ATOM 3502 C CB . GLN A 1 439 ? 3.777 4.626 17.782 1.00 3.53 ? 439 GLN A CB 1 ATOM 3503 C CG . GLN A 1 439 ? 4.688 5.677 18.420 1.00 6.85 ? 439 GLN A CG 1 ATOM 3504 C CD . GLN A 1 439 ? 4.609 5.696 19.953 1.00 9.04 ? 439 GLN A CD 1 ATOM 3505 O OE1 . GLN A 1 439 ? 3.530 5.563 20.546 1.00 8.31 ? 439 GLN A OE1 1 ATOM 3506 N NE2 . GLN A 1 439 ? 5.760 5.882 20.597 1.00 10.44 ? 439 GLN A NE2 1 ATOM 3507 N N . ARG A 1 440 ? 2.356 5.681 15.338 1.00 2.00 ? 440 ARG A N 1 ATOM 3508 C CA . ARG A 1 440 ? 2.275 6.534 14.166 1.00 2.38 ? 440 ARG A CA 1 ATOM 3509 C C . ARG A 1 440 ? 0.992 7.386 14.012 1.00 3.73 ? 440 ARG A C 1 ATOM 3510 O O . ARG A 1 440 ? 1.002 8.396 13.301 1.00 4.27 ? 440 ARG A O 1 ATOM 3511 C CB . ARG A 1 440 ? 2.473 5.663 12.929 1.00 2.84 ? 440 ARG A CB 1 ATOM 3512 C CG . ARG A 1 440 ? 2.498 6.393 11.595 1.00 4.29 ? 440 ARG A CG 1 ATOM 3513 C CD . ARG A 1 440 ? 3.751 7.190 11.432 1.00 5.09 ? 440 ARG A CD 1 ATOM 3514 N NE . ARG A 1 440 ? 4.868 6.413 10.950 1.00 5.13 ? 440 ARG A NE 1 ATOM 3515 C CZ . ARG A 1 440 ? 6.116 6.756 11.199 1.00 6.40 ? 440 ARG A CZ 1 ATOM 3516 N NH1 . ARG A 1 440 ? 6.365 7.822 11.924 1.00 7.16 ? 440 ARG A NH1 1 ATOM 3517 N NH2 . ARG A 1 440 ? 7.106 6.030 10.714 1.00 4.80 ? 440 ARG A NH2 1 ATOM 3518 N N . CYS A 1 441 ? -0.111 6.989 14.648 1.00 3.86 ? 441 CYS A N 1 ATOM 3519 C CA . CYS A 1 441 ? -1.349 7.772 14.549 1.00 2.00 ? 441 CYS A CA 1 ATOM 3520 C C . CYS A 1 441 ? -1.195 9.005 15.407 1.00 2.00 ? 441 CYS A C 1 ATOM 3521 O O . CYS A 1 441 ? -1.492 10.121 14.990 1.00 2.32 ? 441 CYS A O 1 ATOM 3522 C CB . CYS A 1 441 ? -2.551 6.999 15.077 1.00 2.00 ? 441 CYS A CB 1 ATOM 3523 S SG . CYS A 1 441 ? -3.050 5.596 14.115 1.00 2.00 ? 441 CYS A SG 1 ATOM 3524 N N . ARG A 1 442 ? -0.737 8.780 16.628 1.00 2.00 ? 442 ARG A N 1 ATOM 3525 C CA . ARG A 1 442 ? -0.547 9.856 17.571 1.00 2.00 ? 442 ARG A CA 1 ATOM 3526 C C . ARG A 1 442 ? 0.479 10.843 17.031 1.00 2.42 ? 442 ARG A C 1 ATOM 3527 O O . ARG A 1 442 ? 0.393 12.035 17.314 1.00 2.95 ? 442 ARG A O 1 ATOM 3528 C CB . ARG A 1 442 ? -0.140 9.257 18.912 1.00 2.00 ? 442 ARG A CB 1 ATOM 3529 C CG . ARG A 1 442 ? -1.210 8.294 19.409 1.00 2.00 ? 442 ARG A CG 1 ATOM 3530 C CD . ARG A 1 442 ? -0.695 7.310 20.428 1.00 2.40 ? 442 ARG A CD 1 ATOM 3531 N NE . ARG A 1 442 ? -1.691 6.285 20.723 1.00 2.00 ? 442 ARG A NE 1 ATOM 3532 C CZ . ARG A 1 442 ? -1.586 5.416 21.718 1.00 2.00 ? 442 ARG A CZ 1 ATOM 3533 N NH1 . ARG A 1 442 ? -0.532 5.443 22.520 1.00 2.00 ? 442 ARG A NH1 1 ATOM 3534 N NH2 . ARG A 1 442 ? -2.540 4.527 21.917 1.00 2.00 ? 442 ARG A NH2 1 ATOM 3535 N N . ASP A 1 443 ? 1.424 10.353 16.227 1.00 2.10 ? 443 ASP A N 1 ATOM 3536 C CA . ASP A 1 443 ? 2.465 11.197 15.611 1.00 2.95 ? 443 ASP A CA 1 ATOM 3537 C C . ASP A 1 443 ? 1.843 12.082 14.512 1.00 2.86 ? 443 ASP A C 1 ATOM 3538 O O . ASP A 1 443 ? 2.162 13.270 14.382 1.00 2.00 ? 443 ASP A O 1 ATOM 3539 C CB . ASP A 1 443 ? 3.587 10.295 15.032 1.00 2.43 ? 443 ASP A CB 1 ATOM 3540 C CG . ASP A 1 443 ? 4.687 11.075 14.276 1.00 2.30 ? 443 ASP A CG 1 ATOM 3541 O OD1 . ASP A 1 443 ? 5.072 12.190 14.702 1.00 2.00 ? 443 ASP A OD1 1 ATOM 3542 O OD2 . ASP A 1 443 ? 5.189 10.541 13.256 1.00 2.00 ? 443 ASP A OD2 1 ATOM 3543 N N . HIS A 1 444 ? 0.934 11.491 13.746 1.00 2.00 ? 444 HIS A N 1 ATOM 3544 C CA . HIS A 1 444 ? 0.261 12.181 12.660 1.00 2.00 ? 444 HIS A CA 1 ATOM 3545 C C . HIS A 1 444 ? -0.896 13.058 13.099 1.00 2.00 ? 444 HIS A C 1 ATOM 3546 O O . HIS A 1 444 ? -1.618 13.597 12.268 1.00 2.00 ? 444 HIS A O 1 ATOM 3547 C CB . HIS A 1 444 ? -0.262 11.129 11.675 1.00 2.35 ? 444 HIS A CB 1 ATOM 3548 C CG . HIS A 1 444 ? 0.731 10.924 10.530 1.00 2.46 ? 444 HIS A CG 1 ATOM 3549 N ND1 . HIS A 1 444 ? 0.643 11.583 9.324 1.00 2.72 ? 444 HIS A ND1 1 ATOM 3550 C CD2 . HIS A 1 444 ? 1.840 10.152 10.460 1.00 2.69 ? 444 HIS A CD2 1 ATOM 3551 C CE1 . HIS A 1 444 ? 1.658 11.228 8.557 1.00 4.05 ? 444 HIS A CE1 1 ATOM 3552 N NE2 . HIS A 1 444 ? 2.400 10.361 9.223 1.00 4.37 ? 444 HIS A NE2 1 ATOM 3553 N N . GLY A 1 445 ? -1.089 13.158 14.433 1.00 2.19 ? 445 GLY A N 1 ATOM 3554 C CA . GLY A 1 445 ? -2.162 13.974 15.021 1.00 2.37 ? 445 GLY A CA 1 ATOM 3555 C C . GLY A 1 445 ? -3.584 13.477 14.728 1.00 2.00 ? 445 GLY A C 1 ATOM 3556 O O . GLY A 1 445 ? -4.527 14.253 14.723 1.00 2.00 ? 445 GLY A O 1 ATOM 3557 N N . MET A 1 446 ? -3.755 12.161 14.471 1.00 2.00 ? 446 MET A N 1 ATOM 3558 C CA . MET A 1 446 ? -5.061 11.535 14.156 1.00 2.00 ? 446 MET A CA 1 ATOM 3559 C C . MET A 1 446 ? -6.159 11.785 15.178 1.00 3.59 ? 446 MET A C 1 ATOM 3560 O O . MET A 1 446 ? -6.035 11.401 16.348 1.00 5.26 ? 446 MET A O 1 ATOM 3561 C CB . MET A 1 446 ? -4.897 10.028 14.041 1.00 2.00 ? 446 MET A CB 1 ATOM 3562 C CG . MET A 1 446 ? -4.306 9.576 12.719 1.00 2.34 ? 446 MET A CG 1 ATOM 3563 S SD . MET A 1 446 ? -5.192 10.264 11.315 1.00 2.00 ? 446 MET A SD 1 ATOM 3564 C CE . MET A 1 446 ? -4.158 11.683 10.936 1.00 2.38 ? 446 MET A CE 1 ATOM 3565 N N . PRO A 1 447 ? -7.251 12.444 14.755 1.00 3.40 ? 447 PRO A N 1 ATOM 3566 C CA . PRO A 1 447 ? -8.403 12.653 15.661 1.00 2.00 ? 447 PRO A CA 1 ATOM 3567 C C . PRO A 1 447 ? -8.811 11.334 16.208 1.00 2.00 ? 447 PRO A C 1 ATOM 3568 O O . PRO A 1 447 ? -8.583 10.314 15.549 1.00 2.00 ? 447 PRO A O 1 ATOM 3569 C CB . PRO A 1 447 ? -9.398 13.377 14.802 1.00 2.00 ? 447 PRO A CB 1 ATOM 3570 C CG . PRO A 1 447 ? -8.486 14.296 14.034 1.00 2.00 ? 447 PRO A CG 1 ATOM 3571 C CD . PRO A 1 447 ? -7.124 13.657 13.966 1.00 2.63 ? 447 PRO A CD 1 ATOM 3572 N N . GLY A 1 448 ? -9.412 11.251 17.388 1.00 2.00 ? 448 GLY A N 1 ATOM 3573 C CA . GLY A 1 448 ? -9.905 9.959 17.856 1.00 2.00 ? 448 GLY A CA 1 ATOM 3574 C C . GLY A 1 448 ? -10.856 9.167 16.966 1.00 2.00 ? 448 GLY A C 1 ATOM 3575 O O . GLY A 1 448 ? -11.241 9.599 15.891 1.00 3.60 ? 448 GLY A O 1 ATOM 3576 N N . TYR A 1 449 ? -11.246 7.993 17.433 1.00 2.00 ? 449 TYR A N 1 ATOM 3577 C CA . TYR A 1 449 ? -12.148 7.124 16.690 1.00 2.00 ? 449 TYR A CA 1 ATOM 3578 C C . TYR A 1 449 ? -13.563 7.668 16.474 1.00 2.43 ? 449 TYR A C 1 ATOM 3579 O O . TYR A 1 449 ? -14.076 7.627 15.364 1.00 2.00 ? 449 TYR A O 1 ATOM 3580 C CB . TYR A 1 449 ? -12.226 5.785 17.410 1.00 2.93 ? 449 TYR A CB 1 ATOM 3581 C CG . TYR A 1 449 ? -13.332 4.856 16.971 1.00 2.37 ? 449 TYR A CG 1 ATOM 3582 C CD1 . TYR A 1 449 ? -13.214 4.086 15.815 1.00 2.81 ? 449 TYR A CD1 1 ATOM 3583 C CD2 . TYR A 1 449 ? -14.464 4.685 17.762 1.00 2.37 ? 449 TYR A CD2 1 ATOM 3584 C CE1 . TYR A 1 449 ? -14.191 3.158 15.468 1.00 2.00 ? 449 TYR A CE1 1 ATOM 3585 C CE2 . TYR A 1 449 ? -15.442 3.765 17.422 1.00 2.00 ? 449 TYR A CE2 1 ATOM 3586 C CZ . TYR A 1 449 ? -15.297 3.005 16.282 1.00 2.00 ? 449 TYR A CZ 1 ATOM 3587 O OH . TYR A 1 449 ? -16.252 2.072 15.977 1.00 3.13 ? 449 TYR A OH 1 ATOM 3588 N N . ASN A 1 450 ? -14.206 8.154 17.531 1.00 4.17 ? 450 ASN A N 1 ATOM 3589 C CA . ASN A 1 450 ? -15.561 8.674 17.398 1.00 3.94 ? 450 ASN A CA 1 ATOM 3590 C C . ASN A 1 450 ? -15.609 9.861 16.478 1.00 3.31 ? 450 ASN A C 1 ATOM 3591 O O . ASN A 1 450 ? -16.530 9.993 15.673 1.00 4.30 ? 450 ASN A O 1 ATOM 3592 C CB . ASN A 1 450 ? -16.127 9.095 18.747 1.00 6.06 ? 450 ASN A CB 1 ATOM 3593 C CG . ASN A 1 450 ? -16.631 7.925 19.551 1.00 8.40 ? 450 ASN A CG 1 ATOM 3594 O OD1 . ASN A 1 450 ? -17.409 7.101 19.059 1.00 9.30 ? 450 ASN A OD1 1 ATOM 3595 N ND2 . ASN A 1 450 ? -16.203 7.848 20.804 1.00 10.66 ? 450 ASN A ND2 1 ATOM 3596 N N . SER A 1 451 ? -14.615 10.732 16.607 1.00 2.91 ? 451 SER A N 1 ATOM 3597 C CA . SER A 1 451 ? -14.553 11.927 15.786 1.00 3.02 ? 451 SER A CA 1 ATOM 3598 C C . SER A 1 451 ? -14.589 11.580 14.294 1.00 4.41 ? 451 SER A C 1 ATOM 3599 O O . SER A 1 451 ? -14.746 12.459 13.442 1.00 5.07 ? 451 SER A O 1 ATOM 3600 C CB . SER A 1 451 ? -13.301 12.722 16.123 1.00 2.00 ? 451 SER A CB 1 ATOM 3601 O OG . SER A 1 451 ? -13.601 14.102 16.105 1.00 5.72 ? 451 SER A OG 1 ATOM 3602 N N . TRP A 1 452 ? -14.444 10.293 13.985 1.00 4.05 ? 452 TRP A N 1 ATOM 3603 C CA . TRP A 1 452 ? -14.495 9.819 12.611 1.00 2.00 ? 452 TRP A CA 1 ATOM 3604 C C . TRP A 1 452 ? -15.823 9.136 12.339 1.00 2.55 ? 452 TRP A C 1 ATOM 3605 O O . TRP A 1 452 ? -16.368 9.285 11.256 1.00 4.50 ? 452 TRP A O 1 ATOM 3606 C CB . TRP A 1 452 ? -13.354 8.858 12.322 1.00 2.00 ? 452 TRP A CB 1 ATOM 3607 C CG . TRP A 1 452 ? -12.021 9.532 12.298 1.00 2.94 ? 452 TRP A CG 1 ATOM 3608 C CD1 . TRP A 1 452 ? -10.998 9.367 13.186 1.00 2.10 ? 452 TRP A CD1 1 ATOM 3609 C CD2 . TRP A 1 452 ? -11.565 10.491 11.338 1.00 3.47 ? 452 TRP A CD2 1 ATOM 3610 N NE1 . TRP A 1 452 ? -9.930 10.161 12.841 1.00 2.02 ? 452 TRP A NE1 1 ATOM 3611 C CE2 . TRP A 1 452 ? -10.251 10.861 11.709 1.00 2.35 ? 452 TRP A CE2 1 ATOM 3612 C CE3 . TRP A 1 452 ? -12.138 11.074 10.199 1.00 2.00 ? 452 TRP A CE3 1 ATOM 3613 C CZ2 . TRP A 1 452 ? -9.503 11.786 10.986 1.00 2.00 ? 452 TRP A CZ2 1 ATOM 3614 C CZ3 . TRP A 1 452 ? -11.395 11.992 9.484 1.00 2.00 ? 452 TRP A CZ3 1 ATOM 3615 C CH2 . TRP A 1 452 ? -10.089 12.338 9.880 1.00 2.00 ? 452 TRP A CH2 1 ATOM 3616 N N . ARG A 1 453 ? -16.351 8.376 13.296 1.00 2.76 ? 453 ARG A N 1 ATOM 3617 C CA . ARG A 1 453 ? -17.652 7.741 13.074 1.00 2.61 ? 453 ARG A CA 1 ATOM 3618 C C . ARG A 1 453 ? -18.617 8.874 12.737 1.00 2.92 ? 453 ARG A C 1 ATOM 3619 O O . ARG A 1 453 ? -19.494 8.742 11.875 1.00 2.00 ? 453 ARG A O 1 ATOM 3620 C CB . ARG A 1 453 ? -18.152 7.026 14.335 1.00 2.00 ? 453 ARG A CB 1 ATOM 3621 C CG . ARG A 1 453 ? -17.477 5.700 14.640 1.00 2.31 ? 453 ARG A CG 1 ATOM 3622 C CD . ARG A 1 453 ? -18.117 4.532 13.890 1.00 2.71 ? 453 ARG A CD 1 ATOM 3623 N NE . ARG A 1 453 ? -19.521 4.333 14.256 1.00 4.01 ? 453 ARG A NE 1 ATOM 3624 C CZ . ARG A 1 453 ? -20.243 3.264 13.921 1.00 4.13 ? 453 ARG A CZ 1 ATOM 3625 N NH1 . ARG A 1 453 ? -19.692 2.292 13.208 1.00 4.26 ? 453 ARG A NH1 1 ATOM 3626 N NH2 . ARG A 1 453 ? -21.513 3.161 14.300 1.00 3.75 ? 453 ARG A NH2 1 ATOM 3627 N N . GLY A 1 454 ? -18.430 9.996 13.428 1.00 2.25 ? 454 GLY A N 1 ATOM 3628 C CA . GLY A 1 454 ? -19.278 11.150 13.214 1.00 3.39 ? 454 GLY A CA 1 ATOM 3629 C C . GLY A 1 454 ? -19.060 11.742 11.839 1.00 4.44 ? 454 GLY A C 1 ATOM 3630 O O . GLY A 1 454 ? -20.023 12.006 11.113 1.00 3.66 ? 454 GLY A O 1 ATOM 3631 N N . PHE A 1 455 ? -17.791 11.947 11.485 1.00 4.72 ? 455 PHE A N 1 ATOM 3632 C CA . PHE A 1 455 ? -17.432 12.512 10.188 1.00 2.27 ? 455 PHE A CA 1 ATOM 3633 C C . PHE A 1 455 ? -18.089 11.763 9.039 1.00 2.00 ? 455 PHE A C 1 ATOM 3634 O O . PHE A 1 455 ? -18.396 12.361 8.017 1.00 2.75 ? 455 PHE A O 1 ATOM 3635 C CB . PHE A 1 455 ? -15.917 12.496 9.977 1.00 2.73 ? 455 PHE A CB 1 ATOM 3636 C CG . PHE A 1 455 ? -15.504 12.808 8.559 1.00 3.54 ? 455 PHE A CG 1 ATOM 3637 C CD1 . PHE A 1 455 ? -15.552 14.114 8.074 1.00 3.18 ? 455 PHE A CD1 1 ATOM 3638 C CD2 . PHE A 1 455 ? -15.105 11.788 7.695 1.00 2.18 ? 455 PHE A CD2 1 ATOM 3639 C CE1 . PHE A 1 455 ? -15.210 14.396 6.754 1.00 2.80 ? 455 PHE A CE1 1 ATOM 3640 C CE2 . PHE A 1 455 ? -14.762 12.061 6.375 1.00 2.00 ? 455 PHE A CE2 1 ATOM 3641 C CZ . PHE A 1 455 ? -14.815 13.363 5.905 1.00 2.00 ? 455 PHE A CZ 1 ATOM 3642 N N . CYS A 1 456 ? -18.287 10.458 9.193 1.00 2.00 ? 456 CYS A N 1 ATOM 3643 C CA . CYS A 1 456 ? -18.926 9.673 8.144 1.00 2.15 ? 456 CYS A CA 1 ATOM 3644 C C . CYS A 1 456 ? -20.421 9.574 8.416 1.00 2.27 ? 456 CYS A C 1 ATOM 3645 O O . CYS A 1 456 ? -21.155 8.923 7.674 1.00 2.00 ? 456 CYS A O 1 ATOM 3646 C CB . CYS A 1 456 ? -18.319 8.275 8.069 1.00 2.36 ? 456 CYS A CB 1 ATOM 3647 S SG . CYS A 1 456 ? -16.600 8.195 7.465 1.00 2.00 ? 456 CYS A SG 1 ATOM 3648 N N . GLY A 1 457 ? -20.856 10.220 9.495 1.00 2.47 ? 457 GLY A N 1 ATOM 3649 C CA . GLY A 1 457 ? -22.262 10.221 9.854 1.00 2.74 ? 457 GLY A CA 1 ATOM 3650 C C . GLY A 1 457 ? -22.798 8.893 10.348 1.00 3.35 ? 457 GLY A C 1 ATOM 3651 O O . GLY A 1 457 ? -23.723 8.322 9.751 1.00 2.13 ? 457 GLY A O 1 ATOM 3652 N N . LEU A 1 458 ? -22.149 8.398 11.436 1.00 3.26 ? 458 LEU A N 1 ATOM 3653 C CA . LEU A 1 458 ? -22.511 7.137 12.129 1.00 3.12 ? 458 LEU A CA 1 ATOM 3654 C C . LEU A 1 458 ? -22.445 7.331 13.642 1.00 4.28 ? 458 LEU A C 1 ATOM 3655 O O . LEU A 1 458 ? -21.724 8.155 14.175 1.00 3.06 ? 458 LEU A O 1 ATOM 3656 C CB . LEU A 1 458 ? -21.628 5.919 11.750 1.00 2.00 ? 458 LEU A CB 1 ATOM 3657 C CG . LEU A 1 458 ? -20.807 5.871 10.446 1.00 2.00 ? 458 LEU A CG 1 ATOM 3658 C CD1 . LEU A 1 458 ? -19.937 4.619 10.420 1.00 2.00 ? 458 LEU A CD1 1 ATOM 3659 C CD2 . LEU A 1 458 ? -21.705 5.924 9.231 1.00 2.51 ? 458 LEU A CD2 1 ATOM 3660 N N . SER A 1 459 ? -23.301 6.466 14.263 1.00 5.40 ? 459 SER A N 1 ATOM 3661 C CA . SER A 1 459 ? -23.485 6.340 15.683 1.00 6.20 ? 459 SER A CA 1 ATOM 3662 C C . SER A 1 459 ? -22.143 6.454 16.369 1.00 7.14 ? 459 SER A C 1 ATOM 3663 O O . SER A 1 459 ? -21.125 5.875 15.985 1.00 8.53 ? 459 SER A O 1 ATOM 3664 C CB . SER A 1 459 ? -24.180 5.031 16.054 1.00 6.25 ? 459 SER A CB 1 ATOM 3665 O OG . SER A 1 459 ? -24.549 5.019 17.425 1.00 10.08 ? 459 SER A OG 1 ATOM 3666 N N . GLN A 1 460 ? -22.224 7.252 17.376 1.00 7.61 ? 460 GLN A N 1 ATOM 3667 C CA . GLN A 1 460 ? -21.104 7.444 18.191 1.00 8.54 ? 460 GLN A CA 1 ATOM 3668 C C . GLN A 1 460 ? -21.452 6.735 19.505 1.00 7.79 ? 460 GLN A C 1 ATOM 3669 O O . GLN A 1 460 ? -22.354 7.158 20.235 1.00 9.39 ? 460 GLN A O 1 ATOM 3670 C CB . GLN A 1 460 ? -20.753 8.954 18.242 1.00 8.47 ? 460 GLN A CB 1 ATOM 3671 C CG . GLN A 1 460 ? -20.661 9.669 16.864 1.00 8.11 ? 460 GLN A CG 1 ATOM 3672 C CD . GLN A 1 460 ? -20.191 11.124 16.904 1.00 8.80 ? 460 GLN A CD 1 ATOM 3673 O OE1 . GLN A 1 460 ? -19.025 11.410 17.222 1.00 8.11 ? 460 GLN A OE1 1 ATOM 3674 N NE2 . GLN A 1 460 ? -20.914 12.203 16.613 1.00 8.48 ? 460 GLN A NE2 1 ATOM 3675 N N . PRO A 1 461 ? -20.727 5.619 19.783 1.00 6.15 ? 461 PRO A N 1 ATOM 3676 C CA . PRO A 1 461 ? -20.842 4.948 21.081 1.00 9.31 ? 461 PRO A CA 1 ATOM 3677 C C . PRO A 1 461 ? -20.055 5.566 22.236 1.00 8.78 ? 461 PRO A C 1 ATOM 3678 O O . PRO A 1 461 ? -18.861 5.849 22.106 1.00 7.91 ? 461 PRO A O 1 ATOM 3679 C CB . PRO A 1 461 ? -20.382 3.527 20.770 1.00 8.22 ? 461 PRO A CB 1 ATOM 3680 C CG . PRO A 1 461 ? -19.332 3.763 19.738 1.00 8.24 ? 461 PRO A CG 1 ATOM 3681 C CD . PRO A 1 461 ? -20.022 4.756 18.821 1.00 7.22 ? 461 PRO A CD 1 ATOM 3682 N N . LYS A 1 462 ? -20.742 5.750 23.367 1.00 8.46 ? 462 LYS A N 1 ATOM 3683 C CA . LYS A 1 462 ? -20.147 6.318 24.573 1.00 7.88 ? 462 LYS A CA 1 ATOM 3684 C C . LYS A 1 462 ? -19.964 5.265 25.663 1.00 8.46 ? 462 LYS A C 1 ATOM 3685 O O . LYS A 1 462 ? -18.975 5.280 26.392 1.00 8.35 ? 462 LYS A O 1 ATOM 3686 C CB . LYS A 1 462 ? -21.020 7.453 25.103 1.00 6.67 ? 462 LYS A CB 1 ATOM 3687 C CG . LYS A 1 462 ? -20.847 8.758 24.355 1.00 7.73 ? 462 LYS A CG 1 ATOM 3688 C CD . LYS A 1 462 ? -19.478 9.346 24.665 1.00 8.88 ? 462 LYS A CD 1 ATOM 3689 C CE . LYS A 1 462 ? -19.236 10.675 23.959 1.00 8.41 ? 462 LYS A CE 1 ATOM 3690 N NZ . LYS A 1 462 ? -17.905 11.220 24.346 1.00 4.68 ? 462 LYS A NZ 1 ATOM 3691 N N . THR A 1 463 ? -20.912 4.341 25.767 1.00 8.46 ? 463 THR A N 1 ATOM 3692 C CA . THR A 1 463 ? -20.827 3.306 26.789 1.00 7.25 ? 463 THR A CA 1 ATOM 3693 C C . THR A 1 463 ? -20.257 2.023 26.251 1.00 9.17 ? 463 THR A C 1 ATOM 3694 O O . THR A 1 463 ? -20.091 1.859 25.044 1.00 10.95 ? 463 THR A O 1 ATOM 3695 C CB . THR A 1 463 ? -22.185 2.928 27.321 1.00 7.58 ? 463 THR A CB 1 ATOM 3696 O OG1 . THR A 1 463 ? -22.910 2.258 26.283 1.00 6.17 ? 463 THR A OG1 1 ATOM 3697 C CG2 . THR A 1 463 ? -22.941 4.163 27.772 1.00 9.31 ? 463 THR A CG2 1 ATOM 3698 N N . LEU A 1 464 ? -19.992 1.105 27.175 1.00 9.45 ? 464 LEU A N 1 ATOM 3699 C CA . LEU A 1 464 ? -19.467 -0.216 26.861 1.00 8.56 ? 464 LEU A CA 1 ATOM 3700 C C . LEU A 1 464 ? -20.602 -0.958 26.176 1.00 8.06 ? 464 LEU A C 1 ATOM 3701 O O . LEU A 1 464 ? -20.390 -1.691 25.222 1.00 8.02 ? 464 LEU A O 1 ATOM 3702 C CB . LEU A 1 464 ? -19.037 -0.922 28.159 1.00 9.27 ? 464 LEU A CB 1 ATOM 3703 C CG . LEU A 1 464 ? -18.592 -2.393 28.297 1.00 9.40 ? 464 LEU A CG 1 ATOM 3704 C CD1 . LEU A 1 464 ? -19.776 -3.236 28.747 1.00 8.90 ? 464 LEU A CD1 1 ATOM 3705 C CD2 . LEU A 1 464 ? -17.982 -2.919 27.007 1.00 8.07 ? 464 LEU A CD2 1 ATOM 3706 N N . LYS A 1 465 ? -21.820 -0.755 26.652 1.00 10.22 ? 465 LYS A N 1 ATOM 3707 C CA . LYS A 1 465 ? -22.950 -1.417 26.017 1.00 13.75 ? 465 LYS A CA 1 ATOM 3708 C C . LYS A 1 465 ? -23.050 -0.767 24.646 1.00 10.32 ? 465 LYS A C 1 ATOM 3709 O O . LYS A 1 465 ? -23.632 -1.323 23.718 1.00 8.67 ? 465 LYS A O 1 ATOM 3710 C CB . LYS A 1 465 ? -24.251 -1.197 26.824 1.00 19.21 ? 465 LYS A CB 1 ATOM 3711 C CG . LYS A 1 465 ? -25.469 -2.040 26.366 1.00 23.44 ? 465 LYS A CG 1 ATOM 3712 C CD . LYS A 1 465 ? -26.626 -1.976 27.384 1.00 26.34 ? 465 LYS A CD 1 ATOM 3713 C CE . LYS A 1 465 ? -27.784 -2.947 27.042 1.00 28.94 ? 465 LYS A CE 1 ATOM 3714 N NZ . LYS A 1 465 ? -27.738 -4.290 27.735 1.00 29.09 ? 465 LYS A NZ 1 ATOM 3715 N N . GLY A 1 466 ? -22.460 0.417 24.531 1.00 9.67 ? 466 GLY A N 1 ATOM 3716 C CA . GLY A 1 466 ? -22.488 1.133 23.270 1.00 9.06 ? 466 GLY A CA 1 ATOM 3717 C C . GLY A 1 466 ? -21.530 0.550 22.252 1.00 7.85 ? 466 GLY A C 1 ATOM 3718 O O . GLY A 1 466 ? -21.910 0.240 21.120 1.00 7.60 ? 466 GLY A O 1 ATOM 3719 N N . LEU A 1 467 ? -20.280 0.388 22.665 1.00 6.47 ? 467 LEU A N 1 ATOM 3720 C CA . LEU A 1 467 ? -19.265 -0.146 21.781 1.00 6.22 ? 467 LEU A CA 1 ATOM 3721 C C . LEU A 1 467 ? -19.478 -1.612 21.401 1.00 8.27 ? 467 LEU A C 1 ATOM 3722 O O . LEU A 1 467 ? -18.879 -2.090 20.435 1.00 9.33 ? 467 LEU A O 1 ATOM 3723 C CB . LEU A 1 467 ? -17.887 0.018 22.409 1.00 3.54 ? 467 LEU A CB 1 ATOM 3724 C CG . LEU A 1 467 ? -16.779 -0.084 21.367 1.00 2.20 ? 467 LEU A CG 1 ATOM 3725 C CD1 . LEU A 1 467 ? -16.834 1.132 20.445 1.00 2.00 ? 467 LEU A CD1 1 ATOM 3726 C CD2 . LEU A 1 467 ? -15.439 -0.174 22.059 1.00 2.01 ? 467 LEU A CD2 1 ATOM 3727 N N . GLN A 1 468 ? -20.327 -2.320 22.144 1.00 8.09 ? 468 GLN A N 1 ATOM 3728 C CA . GLN A 1 468 ? -20.590 -3.736 21.859 1.00 8.11 ? 468 GLN A CA 1 ATOM 3729 C C . GLN A 1 468 ? -21.574 -3.930 20.708 1.00 6.75 ? 468 GLN A C 1 ATOM 3730 O O . GLN A 1 468 ? -21.448 -4.864 19.918 1.00 2.01 ? 468 GLN A O 1 ATOM 3731 C CB . GLN A 1 468 ? -21.144 -4.437 23.098 1.00 10.80 ? 468 GLN A CB 1 ATOM 3732 C CG . GLN A 1 468 ? -20.259 -4.357 24.319 1.00 14.01 ? 468 GLN A CG 1 ATOM 3733 C CD . GLN A 1 468 ? -20.931 -4.937 25.547 1.00 15.87 ? 468 GLN A CD 1 ATOM 3734 O OE1 . GLN A 1 468 ? -20.428 -4.806 26.661 1.00 18.16 ? 468 GLN A OE1 1 ATOM 3735 N NE2 . GLN A 1 468 ? -22.074 -5.588 25.348 1.00 16.68 ? 468 GLN A NE2 1 ATOM 3736 N N . ALA A 1 469 ? -22.556 -3.041 20.634 1.00 7.02 ? 469 ALA A N 1 ATOM 3737 C CA . ALA A 1 469 ? -23.578 -3.088 19.596 1.00 8.19 ? 469 ALA A CA 1 ATOM 3738 C C . ALA A 1 469 ? -22.970 -2.912 18.207 1.00 9.12 ? 469 ALA A C 1 ATOM 3739 O O . ALA A 1 469 ? -23.453 -3.494 17.228 1.00 10.31 ? 469 ALA A O 1 ATOM 3740 C CB . ALA A 1 469 ? -24.616 -2.000 19.850 1.00 7.42 ? 469 ALA A CB 1 ATOM 3741 N N . VAL A 1 470 ? -21.914 -2.104 18.126 1.00 8.89 ? 470 VAL A N 1 ATOM 3742 C CA . VAL A 1 470 ? -21.236 -1.836 16.858 1.00 8.29 ? 470 VAL A CA 1 ATOM 3743 C C . VAL A 1 470 ? -20.253 -2.938 16.468 1.00 7.23 ? 470 VAL A C 1 ATOM 3744 O O . VAL A 1 470 ? -20.304 -3.469 15.357 1.00 5.60 ? 470 VAL A O 1 ATOM 3745 C CB . VAL A 1 470 ? -20.474 -0.487 16.916 1.00 8.54 ? 470 VAL A CB 1 ATOM 3746 C CG1 . VAL A 1 470 ? -19.509 -0.368 15.744 1.00 6.40 ? 470 VAL A CG1 1 ATOM 3747 C CG2 . VAL A 1 470 ? -21.466 0.663 16.882 1.00 8.28 ? 470 VAL A CG2 1 ATOM 3748 N N . LEU A 1 471 ? -19.355 -3.267 17.391 1.00 7.19 ? 471 LEU A N 1 ATOM 3749 C CA . LEU A 1 471 ? -18.352 -4.296 17.157 1.00 7.64 ? 471 LEU A CA 1 ATOM 3750 C C . LEU A 1 471 ? -18.983 -5.685 17.070 1.00 8.63 ? 471 LEU A C 1 ATOM 3751 O O . LEU A 1 471 ? -18.392 -6.613 16.511 1.00 9.00 ? 471 LEU A O 1 ATOM 3752 C CB . LEU A 1 471 ? -17.292 -4.235 18.270 1.00 4.29 ? 471 LEU A CB 1 ATOM 3753 C CG . LEU A 1 471 ? -16.101 -3.285 18.046 1.00 2.33 ? 471 LEU A CG 1 ATOM 3754 C CD1 . LEU A 1 471 ? -16.414 -2.279 16.963 1.00 2.92 ? 471 LEU A CD1 1 ATOM 3755 C CD2 . LEU A 1 471 ? -15.750 -2.577 19.328 1.00 2.00 ? 471 LEU A CD2 1 ATOM 3756 N N . LYS A 1 472 ? -20.200 -5.811 17.594 1.00 10.26 ? 472 LYS A N 1 ATOM 3757 C CA . LYS A 1 472 ? -20.914 -7.086 17.595 1.00 11.49 ? 472 LYS A CA 1 ATOM 3758 C C . LYS A 1 472 ? -20.072 -8.127 18.326 1.00 12.25 ? 472 LYS A C 1 ATOM 3759 O O . LYS A 1 472 ? -20.115 -9.316 18.013 1.00 12.34 ? 472 LYS A O 1 ATOM 3760 C CB . LYS A 1 472 ? -21.191 -7.559 16.162 1.00 11.92 ? 472 LYS A CB 1 ATOM 3761 C CG . LYS A 1 472 ? -22.665 -7.696 15.834 1.00 12.69 ? 472 LYS A CG 1 ATOM 3762 C CD . LYS A 1 472 ? -23.306 -6.334 15.646 1.00 16.04 ? 472 LYS A CD 1 ATOM 3763 C CE . LYS A 1 472 ? -24.831 -6.396 15.772 1.00 19.48 ? 472 LYS A CE 1 ATOM 3764 N NZ . LYS A 1 472 ? -25.475 -7.445 14.916 1.00 20.21 ? 472 LYS A NZ 1 ATOM 3765 N N . ASN A 1 473 ? -19.309 -7.664 19.310 1.00 12.50 ? 473 ASN A N 1 ATOM 3766 C CA . ASN A 1 473 ? -18.439 -8.537 20.084 1.00 13.78 ? 473 ASN A CA 1 ATOM 3767 C C . ASN A 1 473 ? -18.243 -7.954 21.488 1.00 15.80 ? 473 ASN A C 1 ATOM 3768 O O . ASN A 1 473 ? -17.534 -6.963 21.655 1.00 16.21 ? 473 ASN A O 1 ATOM 3769 C CB . ASN A 1 473 ? -17.094 -8.653 19.368 1.00 14.23 ? 473 ASN A CB 1 ATOM 3770 C CG . ASN A 1 473 ? -16.150 -9.598 20.063 1.00 15.54 ? 473 ASN A CG 1 ATOM 3771 O OD1 . ASN A 1 473 ? -15.853 -9.438 21.250 1.00 15.92 ? 473 ASN A OD1 1 ATOM 3772 N ND2 . ASN A 1 473 ? -15.669 -10.595 19.328 1.00 15.67 ? 473 ASN A ND2 1 ATOM 3773 N N . LYS A 1 474 ? -18.856 -8.566 22.499 1.00 17.16 ? 474 LYS A N 1 ATOM 3774 C CA . LYS A 1 474 ? -18.742 -8.042 23.862 1.00 18.48 ? 474 LYS A CA 1 ATOM 3775 C C . LYS A 1 474 ? -17.286 -7.995 24.338 1.00 18.75 ? 474 LYS A C 1 ATOM 3776 O O . LYS A 1 474 ? -16.697 -6.919 24.493 1.00 18.60 ? 474 LYS A O 1 ATOM 3777 C CB . LYS A 1 474 ? -19.556 -8.896 24.846 1.00 22.54 ? 474 LYS A CB 1 ATOM 3778 C CG . LYS A 1 474 ? -21.008 -9.214 24.456 1.00 27.25 ? 474 LYS A CG 1 ATOM 3779 C CD . LYS A 1 474 ? -21.547 -10.337 25.369 1.00 30.59 ? 474 LYS A CD 1 ATOM 3780 C CE . LYS A 1 474 ? -22.818 -11.014 24.833 1.00 32.88 ? 474 LYS A CE 1 ATOM 3781 N NZ . LYS A 1 474 ? -23.019 -12.386 25.435 1.00 34.45 ? 474 LYS A NZ 1 ATOM 3782 N N . ILE A 1 475 ? -16.718 -9.173 24.575 1.00 16.92 ? 475 ILE A N 1 ATOM 3783 C CA . ILE A 1 475 ? -15.346 -9.302 25.041 1.00 14.08 ? 475 ILE A CA 1 ATOM 3784 C C . ILE A 1 475 ? -14.397 -8.277 24.423 1.00 13.32 ? 475 ILE A C 1 ATOM 3785 O O . ILE A 1 475 ? -13.629 -7.637 25.142 1.00 13.63 ? 475 ILE A O 1 ATOM 3786 C CB . ILE A 1 475 ? -14.822 -10.720 24.768 1.00 14.63 ? 475 ILE A CB 1 ATOM 3787 C CG1 . ILE A 1 475 ? -13.296 -10.720 24.723 1.00 15.55 ? 475 ILE A CG1 1 ATOM 3788 C CG2 . ILE A 1 475 ? -15.411 -11.240 23.483 1.00 15.22 ? 475 ILE A CG2 1 ATOM 3789 C CD1 . ILE A 1 475 ? -12.653 -10.273 26.015 1.00 17.27 ? 475 ILE A CD1 1 ATOM 3790 N N . LEU A 1 476 ? -14.444 -8.116 23.102 1.00 11.61 ? 476 LEU A N 1 ATOM 3791 C CA . LEU A 1 476 ? -13.562 -7.151 22.443 1.00 9.88 ? 476 LEU A CA 1 ATOM 3792 C C . LEU A 1 476 ? -13.828 -5.749 22.961 1.00 8.09 ? 476 LEU A C 1 ATOM 3793 O O . LEU A 1 476 ? -12.921 -5.080 23.465 1.00 8.71 ? 476 LEU A O 1 ATOM 3794 C CB . LEU A 1 476 ? -13.747 -7.175 20.922 1.00 8.20 ? 476 LEU A CB 1 ATOM 3795 C CG . LEU A 1 476 ? -12.861 -6.206 20.125 1.00 7.45 ? 476 LEU A CG 1 ATOM 3796 C CD1 . LEU A 1 476 ? -11.459 -6.138 20.713 1.00 6.10 ? 476 LEU A CD1 1 ATOM 3797 C CD2 . LEU A 1 476 ? -12.809 -6.668 18.680 1.00 7.53 ? 476 LEU A CD2 1 ATOM 3798 N N . ALA A 1 477 ? -15.077 -5.315 22.843 1.00 5.86 ? 477 ALA A N 1 ATOM 3799 C CA . ALA A 1 477 ? -15.467 -3.992 23.305 1.00 5.89 ? 477 ALA A CA 1 ATOM 3800 C C . ALA A 1 477 ? -14.889 -3.743 24.698 1.00 4.95 ? 477 ALA A C 1 ATOM 3801 O O . ALA A 1 477 ? -14.499 -2.612 25.033 1.00 2.00 ? 477 ALA A O 1 ATOM 3802 C CB . ALA A 1 477 ? -17.000 -3.869 23.325 1.00 4.31 ? 477 ALA A CB 1 ATOM 3803 N N . LYS A 1 478 ? -14.809 -4.807 25.497 1.00 3.74 ? 478 LYS A N 1 ATOM 3804 C CA . LYS A 1 478 ? -14.284 -4.677 26.851 1.00 5.55 ? 478 LYS A CA 1 ATOM 3805 C C . LYS A 1 478 ? -12.769 -4.533 26.896 1.00 5.19 ? 478 LYS A C 1 ATOM 3806 O O . LYS A 1 478 ? -12.251 -3.624 27.543 1.00 6.39 ? 478 LYS A O 1 ATOM 3807 C CB . LYS A 1 478 ? -14.691 -5.864 27.726 1.00 6.14 ? 478 LYS A CB 1 ATOM 3808 C CG . LYS A 1 478 ? -14.550 -5.568 29.225 1.00 8.16 ? 478 LYS A CG 1 ATOM 3809 C CD . LYS A 1 478 ? -14.481 -6.841 30.068 1.00 10.33 ? 478 LYS A CD 1 ATOM 3810 C CE . LYS A 1 478 ? -13.048 -7.121 30.545 1.00 10.87 ? 478 LYS A CE 1 ATOM 3811 N NZ . LYS A 1 478 ? -12.601 -8.527 30.310 1.00 8.84 ? 478 LYS A NZ 1 ATOM 3812 N N . LYS A 1 479 ? -12.062 -5.439 26.228 1.00 4.47 ? 479 LYS A N 1 ATOM 3813 C CA . LYS A 1 479 ? -10.603 -5.403 26.200 1.00 3.78 ? 479 LYS A CA 1 ATOM 3814 C C . LYS A 1 479 ? -10.194 -4.038 25.706 1.00 3.03 ? 479 LYS A C 1 ATOM 3815 O O . LYS A 1 479 ? -9.256 -3.416 26.205 1.00 2.00 ? 479 LYS A O 1 ATOM 3816 C CB . LYS A 1 479 ? -10.062 -6.460 25.231 1.00 5.13 ? 479 LYS A CB 1 ATOM 3817 C CG . LYS A 1 479 ? -10.089 -7.899 25.748 1.00 6.88 ? 479 LYS A CG 1 ATOM 3818 C CD . LYS A 1 479 ? -9.871 -8.906 24.611 1.00 8.56 ? 479 LYS A CD 1 ATOM 3819 C CE . LYS A 1 479 ? -9.366 -10.264 25.121 1.00 9.11 ? 479 LYS A CE 1 ATOM 3820 N NZ . LYS A 1 479 ? -9.261 -11.310 24.049 1.00 7.99 ? 479 LYS A NZ 1 ATOM 3821 N N . LEU A 1 480 ? -10.938 -3.575 24.717 1.00 2.00 ? 480 LEU A N 1 ATOM 3822 C CA . LEU A 1 480 ? -10.664 -2.298 24.100 1.00 2.91 ? 480 LEU A CA 1 ATOM 3823 C C . LEU A 1 480 ? -10.638 -1.120 25.059 1.00 4.77 ? 480 LEU A C 1 ATOM 3824 O O . LEU A 1 480 ? -9.689 -0.334 25.032 1.00 3.96 ? 480 LEU A O 1 ATOM 3825 C CB . LEU A 1 480 ? -11.672 -2.043 22.981 1.00 3.63 ? 480 LEU A CB 1 ATOM 3826 C CG . LEU A 1 480 ? -11.128 -1.397 21.703 1.00 2.72 ? 480 LEU A CG 1 ATOM 3827 C CD1 . LEU A 1 480 ? -9.597 -1.421 21.687 1.00 2.15 ? 480 LEU A CD1 1 ATOM 3828 C CD2 . LEU A 1 480 ? -11.695 -2.150 20.509 1.00 2.00 ? 480 LEU A CD2 1 ATOM 3829 N N . LEU A 1 481 ? -11.660 -0.981 25.905 1.00 5.35 ? 481 LEU A N 1 ATOM 3830 C CA . LEU A 1 481 ? -11.676 0.153 26.835 1.00 5.95 ? 481 LEU A CA 1 ATOM 3831 C C . LEU A 1 481 ? -11.226 -0.123 28.265 1.00 5.93 ? 481 LEU A C 1 ATOM 3832 O O . LEU A 1 481 ? -11.202 0.764 29.116 1.00 4.21 ? 481 LEU A O 1 ATOM 3833 C CB . LEU A 1 481 ? -13.034 0.850 26.813 1.00 6.16 ? 481 LEU A CB 1 ATOM 3834 C CG . LEU A 1 481 ? -14.321 0.057 26.925 1.00 6.17 ? 481 LEU A CG 1 ATOM 3835 C CD1 . LEU A 1 481 ? -14.655 -0.157 28.384 1.00 7.30 ? 481 LEU A CD1 1 ATOM 3836 C CD2 . LEU A 1 481 ? -15.428 0.850 26.242 1.00 7.79 ? 481 LEU A CD2 1 ATOM 3837 N N . ASP A 1 482 ? -10.871 -1.362 28.539 1.00 6.34 ? 482 ASP A N 1 ATOM 3838 C CA . ASP A 1 482 ? -10.329 -1.655 29.839 1.00 7.56 ? 482 ASP A CA 1 ATOM 3839 C C . ASP A 1 482 ? -8.998 -0.954 29.662 1.00 8.18 ? 482 ASP A C 1 ATOM 3840 O O . ASP A 1 482 ? -8.258 -0.715 30.614 1.00 8.96 ? 482 ASP A O 1 ATOM 3841 C CB . ASP A 1 482 ? -10.072 -3.142 29.973 1.00 11.88 ? 482 ASP A CB 1 ATOM 3842 C CG . ASP A 1 482 ? -11.042 -3.806 30.880 1.00 14.61 ? 482 ASP A CG 1 ATOM 3843 O OD1 . ASP A 1 482 ? -12.209 -3.361 30.905 1.00 16.88 ? 482 ASP A OD1 1 ATOM 3844 O OD2 . ASP A 1 482 ? -10.640 -4.774 31.559 1.00 17.44 ? 482 ASP A OD2 1 ATOM 3845 N N . LEU A 1 483 ? -8.715 -0.636 28.400 1.00 7.81 ? 483 LEU A N 1 ATOM 3846 C CA . LEU A 1 483 ? -7.467 -0.002 27.985 1.00 6.61 ? 483 LEU A CA 1 ATOM 3847 C C . LEU A 1 483 ? -7.541 1.469 27.607 1.00 5.56 ? 483 LEU A C 1 ATOM 3848 O O . LEU A 1 483 ? -6.658 2.259 27.958 1.00 4.46 ? 483 LEU A O 1 ATOM 3849 C CB . LEU A 1 483 ? -6.903 -0.765 26.797 1.00 5.17 ? 483 LEU A CB 1 ATOM 3850 C CG . LEU A 1 483 ? -5.803 -1.755 27.109 1.00 4.18 ? 483 LEU A CG 1 ATOM 3851 C CD1 . LEU A 1 483 ? -5.791 -2.801 26.024 1.00 5.60 ? 483 LEU A CD1 1 ATOM 3852 C CD2 . LEU A 1 483 ? -4.473 -1.028 27.210 1.00 4.37 ? 483 LEU A CD2 1 ATOM 3853 N N . TYR A 1 484 ? -8.585 1.811 26.859 1.00 5.10 ? 484 TYR A N 1 ATOM 3854 C CA . TYR A 1 484 ? -8.803 3.165 26.378 1.00 3.91 ? 484 TYR A CA 1 ATOM 3855 C C . TYR A 1 484 ? -9.726 3.940 27.298 1.00 2.69 ? 484 TYR A C 1 ATOM 3856 O O . TYR A 1 484 ? -9.776 5.164 27.259 1.00 2.00 ? 484 TYR A O 1 ATOM 3857 C CB . TYR A 1 484 ? -9.362 3.106 24.952 1.00 4.37 ? 484 TYR A CB 1 ATOM 3858 C CG . TYR A 1 484 ? -8.281 2.926 23.893 1.00 3.88 ? 484 TYR A CG 1 ATOM 3859 C CD1 . TYR A 1 484 ? -7.383 3.958 23.617 1.00 2.62 ? 484 TYR A CD1 1 ATOM 3860 C CD2 . TYR A 1 484 ? -8.157 1.735 23.167 1.00 2.99 ? 484 TYR A CD2 1 ATOM 3861 C CE1 . TYR A 1 484 ? -6.402 3.820 22.656 1.00 2.00 ? 484 TYR A CE1 1 ATOM 3862 C CE2 . TYR A 1 484 ? -7.169 1.590 22.196 1.00 2.00 ? 484 TYR A CE2 1 ATOM 3863 C CZ . TYR A 1 484 ? -6.296 2.643 21.949 1.00 2.00 ? 484 TYR A CZ 1 ATOM 3864 O OH . TYR A 1 484 ? -5.311 2.541 20.997 1.00 2.00 ? 484 TYR A OH 1 ATOM 3865 N N . LYS A 1 485 ? -10.447 3.205 28.133 1.00 4.39 ? 485 LYS A N 1 ATOM 3866 C CA . LYS A 1 485 ? -11.364 3.783 29.110 1.00 4.45 ? 485 LYS A CA 1 ATOM 3867 C C . LYS A 1 485 ? -12.545 4.525 28.497 1.00 4.72 ? 485 LYS A C 1 ATOM 3868 O O . LYS A 1 485 ? -13.567 4.702 29.163 1.00 4.07 ? 485 LYS A O 1 ATOM 3869 C CB . LYS A 1 485 ? -10.600 4.710 30.059 1.00 5.78 ? 485 LYS A CB 1 ATOM 3870 C CG . LYS A 1 485 ? -9.264 4.140 30.548 1.00 7.86 ? 485 LYS A CG 1 ATOM 3871 C CD . LYS A 1 485 ? -9.409 2.889 31.426 1.00 8.42 ? 485 LYS A CD 1 ATOM 3872 C CE . LYS A 1 485 ? -8.027 2.255 31.688 1.00 9.13 ? 485 LYS A CE 1 ATOM 3873 N NZ . LYS A 1 485 ? -7.938 1.366 32.899 1.00 7.04 ? 485 LYS A NZ 1 ATOM 3874 N N . THR A 1 486 ? -12.405 4.964 27.243 1.00 4.24 ? 486 THR A N 1 ATOM 3875 C CA . THR A 1 486 ? -13.489 5.660 26.535 1.00 2.86 ? 486 THR A CA 1 ATOM 3876 C C . THR A 1 486 ? -13.408 5.559 25.020 1.00 3.23 ? 486 THR A C 1 ATOM 3877 O O . THR A 1 486 ? -12.337 5.668 24.426 1.00 3.60 ? 486 THR A O 1 ATOM 3878 C CB . THR A 1 486 ? -13.565 7.166 26.858 1.00 2.24 ? 486 THR A CB 1 ATOM 3879 O OG1 . THR A 1 486 ? -14.738 7.709 26.243 1.00 2.00 ? 486 THR A OG1 1 ATOM 3880 C CG2 . THR A 1 486 ? -12.358 7.909 26.298 1.00 2.16 ? 486 THR A CG2 1 ATOM 3881 N N . PRO A 1 487 ? -14.556 5.352 24.372 1.00 3.29 ? 487 PRO A N 1 ATOM 3882 C CA . PRO A 1 487 ? -14.609 5.242 22.918 1.00 2.82 ? 487 PRO A CA 1 ATOM 3883 C C . PRO A 1 487 ? -13.915 6.414 22.249 1.00 4.20 ? 487 PRO A C 1 ATOM 3884 O O . PRO A 1 487 ? -13.340 6.262 21.169 1.00 4.04 ? 487 PRO A O 1 ATOM 3885 C CB . PRO A 1 487 ? -16.105 5.225 22.635 1.00 3.93 ? 487 PRO A CB 1 ATOM 3886 C CG . PRO A 1 487 ? -16.634 4.461 23.796 1.00 4.97 ? 487 PRO A CG 1 ATOM 3887 C CD . PRO A 1 487 ? -15.870 5.060 24.967 1.00 4.70 ? 487 PRO A CD 1 ATOM 3888 N N . ASP A 1 488 ? -13.967 7.580 22.890 1.00 2.95 ? 488 ASP A N 1 ATOM 3889 C CA . ASP A 1 488 ? -13.346 8.772 22.321 1.00 4.65 ? 488 ASP A CA 1 ATOM 3890 C C . ASP A 1 488 ? -11.833 8.612 22.095 1.00 4.05 ? 488 ASP A C 1 ATOM 3891 O O . ASP A 1 488 ? -11.278 9.172 21.150 1.00 2.47 ? 488 ASP A O 1 ATOM 3892 C CB . ASP A 1 488 ? -13.589 10.011 23.214 1.00 7.00 ? 488 ASP A CB 1 ATOM 3893 C CG . ASP A 1 488 ? -15.074 10.386 23.351 1.00 8.91 ? 488 ASP A CG 1 ATOM 3894 O OD1 . ASP A 1 488 ? -15.853 10.164 22.392 1.00 7.65 ? 488 ASP A OD1 1 ATOM 3895 O OD2 . ASP A 1 488 ? -15.448 10.929 24.424 1.00 8.95 ? 488 ASP A OD2 1 ATOM 3896 N N . ASN A 1 489 ? -11.164 7.835 22.938 1.00 3.33 ? 489 ASN A N 1 ATOM 3897 C CA . ASN A 1 489 ? -9.722 7.691 22.790 1.00 3.23 ? 489 ASN A CA 1 ATOM 3898 C C . ASN A 1 489 ? -9.150 6.545 21.961 1.00 3.23 ? 489 ASN A C 1 ATOM 3899 O O . ASN A 1 489 ? -7.936 6.494 21.761 1.00 4.38 ? 489 ASN A O 1 ATOM 3900 C CB . ASN A 1 489 ? -9.065 7.707 24.170 1.00 3.67 ? 489 ASN A CB 1 ATOM 3901 C CG . ASN A 1 489 ? -9.237 9.040 24.873 1.00 3.85 ? 489 ASN A CG 1 ATOM 3902 O OD1 . ASN A 1 489 ? -9.351 10.086 24.226 1.00 5.05 ? 489 ASN A OD1 1 ATOM 3903 N ND2 . ASN A 1 489 ? -9.243 9.014 26.197 1.00 4.27 ? 489 ASN A ND2 1 ATOM 3904 N N . ILE A 1 490 ? -9.997 5.635 21.479 1.00 3.33 ? 490 ILE A N 1 ATOM 3905 C CA . ILE A 1 490 ? -9.528 4.519 20.645 1.00 2.08 ? 490 ILE A CA 1 ATOM 3906 C C . ILE A 1 490 ? -8.813 5.079 19.410 1.00 2.00 ? 490 ILE A C 1 ATOM 3907 O O . ILE A 1 490 ? -9.353 5.940 18.709 1.00 2.00 ? 490 ILE A O 1 ATOM 3908 C CB . ILE A 1 490 ? -10.716 3.621 20.169 1.00 2.00 ? 490 ILE A CB 1 ATOM 3909 C CG1 . ILE A 1 490 ? -10.831 2.381 21.048 1.00 2.00 ? 490 ILE A CG1 1 ATOM 3910 C CG2 . ILE A 1 490 ? -10.519 3.188 18.730 1.00 2.00 ? 490 ILE A CG2 1 ATOM 3911 C CD1 . ILE A 1 490 ? -12.175 2.223 21.675 1.00 2.00 ? 490 ILE A CD1 1 ATOM 3912 N N . ASP A 1 491 ? -7.600 4.596 19.153 1.00 2.00 ? 491 ASP A N 1 ATOM 3913 C CA . ASP A 1 491 ? -6.831 5.047 17.992 1.00 2.31 ? 491 ASP A CA 1 ATOM 3914 C C . ASP A 1 491 ? -7.566 4.633 16.713 1.00 2.00 ? 491 ASP A C 1 ATOM 3915 O O . ASP A 1 491 ? -8.020 3.498 16.585 1.00 2.00 ? 491 ASP A O 1 ATOM 3916 C CB . ASP A 1 491 ? -5.414 4.449 18.026 1.00 2.54 ? 491 ASP A CB 1 ATOM 3917 C CG . ASP A 1 491 ? -4.495 5.160 19.020 1.00 2.00 ? 491 ASP A CG 1 ATOM 3918 O OD1 . ASP A 1 491 ? -4.347 6.399 18.924 1.00 2.00 ? 491 ASP A OD1 1 ATOM 3919 O OD2 . ASP A 1 491 ? -3.913 4.478 19.889 1.00 2.00 ? 491 ASP A OD2 1 ATOM 3920 N N . ILE A 1 492 ? -7.674 5.543 15.757 1.00 2.00 ? 492 ILE A N 1 ATOM 3921 C CA . ILE A 1 492 ? -8.412 5.231 14.544 1.00 2.00 ? 492 ILE A CA 1 ATOM 3922 C C . ILE A 1 492 ? -8.092 3.856 13.953 1.00 2.42 ? 492 ILE A C 1 ATOM 3923 O O . ILE A 1 492 ? -8.957 2.979 13.935 1.00 2.96 ? 492 ILE A O 1 ATOM 3924 C CB . ILE A 1 492 ? -8.248 6.380 13.484 1.00 2.56 ? 492 ILE A CB 1 ATOM 3925 C CG1 . ILE A 1 492 ? -9.581 6.622 12.756 1.00 2.00 ? 492 ILE A CG1 1 ATOM 3926 C CG2 . ILE A 1 492 ? -7.119 6.076 12.516 1.00 2.76 ? 492 ILE A CG2 1 ATOM 3927 C CD1 . ILE A 1 492 ? -10.000 5.557 11.780 1.00 3.24 ? 492 ILE A CD1 1 ATOM 3928 N N . TRP A 1 493 ? -6.856 3.653 13.509 1.00 2.00 ? 493 TRP A N 1 ATOM 3929 C CA . TRP A 1 493 ? -6.443 2.386 12.908 1.00 2.07 ? 493 TRP A CA 1 ATOM 3930 C C . TRP A 1 493 ? -7.115 1.132 13.481 1.00 2.00 ? 493 TRP A C 1 ATOM 3931 O O . TRP A 1 493 ? -7.776 0.383 12.763 1.00 2.33 ? 493 TRP A O 1 ATOM 3932 C CB . TRP A 1 493 ? -4.928 2.231 13.021 1.00 2.00 ? 493 TRP A CB 1 ATOM 3933 C CG . TRP A 1 493 ? -4.423 1.029 12.310 1.00 2.00 ? 493 TRP A CG 1 ATOM 3934 C CD1 . TRP A 1 493 ? -4.440 0.806 10.966 1.00 2.00 ? 493 TRP A CD1 1 ATOM 3935 C CD2 . TRP A 1 493 ? -3.844 -0.135 12.903 1.00 2.49 ? 493 TRP A CD2 1 ATOM 3936 N NE1 . TRP A 1 493 ? -3.910 -0.425 10.683 1.00 2.00 ? 493 TRP A NE1 1 ATOM 3937 C CE2 . TRP A 1 493 ? -3.537 -1.026 11.855 1.00 2.00 ? 493 TRP A CE2 1 ATOM 3938 C CE3 . TRP A 1 493 ? -3.558 -0.516 14.224 1.00 2.82 ? 493 TRP A CE3 1 ATOM 3939 C CZ2 . TRP A 1 493 ? -2.956 -2.272 12.082 1.00 2.00 ? 493 TRP A CZ2 1 ATOM 3940 C CZ3 . TRP A 1 493 ? -2.979 -1.760 14.450 1.00 2.18 ? 493 TRP A CZ3 1 ATOM 3941 C CH2 . TRP A 1 493 ? -2.686 -2.622 13.382 1.00 2.16 ? 493 TRP A CH2 1 ATOM 3942 N N . ILE A 1 494 ? -6.940 0.906 14.776 1.00 2.00 ? 494 ILE A N 1 ATOM 3943 C CA . ILE A 1 494 ? -7.512 -0.260 15.425 1.00 2.00 ? 494 ILE A CA 1 ATOM 3944 C C . ILE A 1 494 ? -9.026 -0.176 15.490 1.00 2.61 ? 494 ILE A C 1 ATOM 3945 O O . ILE A 1 494 ? -9.724 -1.080 15.031 1.00 2.51 ? 494 ILE A O 1 ATOM 3946 C CB . ILE A 1 494 ? -6.931 -0.426 16.840 1.00 2.00 ? 494 ILE A CB 1 ATOM 3947 C CG1 . ILE A 1 494 ? -7.620 -1.583 17.559 1.00 3.12 ? 494 ILE A CG1 1 ATOM 3948 C CG2 . ILE A 1 494 ? -7.068 0.865 17.610 1.00 2.00 ? 494 ILE A CG2 1 ATOM 3949 C CD1 . ILE A 1 494 ? -6.986 -1.926 18.893 1.00 2.32 ? 494 ILE A CD1 1 ATOM 3950 N N . GLY A 1 495 ? -9.531 0.914 16.058 1.00 3.00 ? 495 GLY A N 1 ATOM 3951 C CA . GLY A 1 495 ? -10.968 1.093 16.160 1.00 2.63 ? 495 GLY A CA 1 ATOM 3952 C C . GLY A 1 495 ? -11.638 0.880 14.818 1.00 2.05 ? 495 GLY A C 1 ATOM 3953 O O . GLY A 1 495 ? -12.679 0.234 14.719 1.00 2.00 ? 495 GLY A O 1 ATOM 3954 N N . GLY A 1 496 ? -11.038 1.432 13.773 1.00 2.00 ? 496 GLY A N 1 ATOM 3955 C CA . GLY A 1 496 ? -11.605 1.259 12.458 1.00 2.00 ? 496 GLY A CA 1 ATOM 3956 C C . GLY A 1 496 ? -11.554 -0.216 12.135 1.00 2.22 ? 496 GLY A C 1 ATOM 3957 O O . GLY A 1 496 ? -12.572 -0.840 11.839 1.00 2.88 ? 496 GLY A O 1 ATOM 3958 N N . ASN A 1 497 ? -10.359 -0.786 12.226 1.00 2.03 ? 497 ASN A N 1 ATOM 3959 C CA . ASN A 1 497 ? -10.171 -2.191 11.914 1.00 2.00 ? 497 ASN A CA 1 ATOM 3960 C C . ASN A 1 497 ? -10.907 -3.148 12.804 1.00 2.03 ? 497 ASN A C 1 ATOM 3961 O O . ASN A 1 497 ? -10.962 -4.346 12.534 1.00 2.00 ? 497 ASN A O 1 ATOM 3962 C CB . ASN A 1 497 ? -8.697 -2.529 11.922 1.00 2.00 ? 497 ASN A CB 1 ATOM 3963 C CG . ASN A 1 497 ? -8.039 -2.138 10.645 1.00 2.47 ? 497 ASN A CG 1 ATOM 3964 O OD1 . ASN A 1 497 ? -7.263 -1.182 10.592 1.00 4.75 ? 497 ASN A OD1 1 ATOM 3965 N ND2 . ASN A 1 497 ? -8.370 -2.858 9.579 1.00 3.12 ? 497 ASN A ND2 1 ATOM 3966 N N . ALA A 1 498 ? -11.488 -2.625 13.867 1.00 2.40 ? 498 ALA A N 1 ATOM 3967 C CA . ALA A 1 498 ? -12.207 -3.484 14.774 1.00 2.19 ? 498 ALA A CA 1 ATOM 3968 C C . ALA A 1 498 ? -13.627 -3.783 14.292 1.00 2.70 ? 498 ALA A C 1 ATOM 3969 O O . ALA A 1 498 ? -14.105 -4.897 14.468 1.00 2.88 ? 498 ALA A O 1 ATOM 3970 C CB . ALA A 1 498 ? -12.227 -2.864 16.166 1.00 2.00 ? 498 ALA A CB 1 ATOM 3971 N N . GLU A 1 499 ? -14.298 -2.815 13.670 1.00 2.00 ? 499 GLU A N 1 ATOM 3972 C CA . GLU A 1 499 ? -15.675 -3.038 13.220 1.00 2.00 ? 499 GLU A CA 1 ATOM 3973 C C . GLU A 1 499 ? -15.812 -4.219 12.253 1.00 2.40 ? 499 GLU A C 1 ATOM 3974 O O . GLU A 1 499 ? -15.026 -4.351 11.312 1.00 2.00 ? 499 GLU A O 1 ATOM 3975 C CB . GLU A 1 499 ? -16.221 -1.779 12.555 1.00 2.00 ? 499 GLU A CB 1 ATOM 3976 C CG . GLU A 1 499 ? -15.823 -0.486 13.239 1.00 2.26 ? 499 GLU A CG 1 ATOM 3977 C CD . GLU A 1 499 ? -16.549 0.721 12.659 1.00 3.60 ? 499 GLU A CD 1 ATOM 3978 O OE1 . GLU A 1 499 ? -16.782 0.751 11.426 1.00 3.30 ? 499 GLU A OE1 1 ATOM 3979 O OE2 . GLU A 1 499 ? -16.878 1.645 13.437 1.00 3.79 ? 499 GLU A OE2 1 ATOM 3980 N N . PRO A 1 500 ? -16.818 -5.094 12.478 1.00 2.55 ? 500 PRO A N 1 ATOM 3981 C CA . PRO A 1 500 ? -17.082 -6.276 11.642 1.00 2.00 ? 500 PRO A CA 1 ATOM 3982 C C . PRO A 1 500 ? -17.389 -5.917 10.190 1.00 2.61 ? 500 PRO A C 1 ATOM 3983 O O . PRO A 1 500 ? -18.097 -4.949 9.926 1.00 3.52 ? 500 PRO A O 1 ATOM 3984 C CB . PRO A 1 500 ? -18.256 -6.948 12.352 1.00 2.00 ? 500 PRO A CB 1 ATOM 3985 C CG . PRO A 1 500 ? -18.938 -5.814 13.040 1.00 2.00 ? 500 PRO A CG 1 ATOM 3986 C CD . PRO A 1 500 ? -17.790 -5.017 13.583 1.00 2.00 ? 500 PRO A CD 1 ATOM 3987 N N . MET A 1 501 ? -16.868 -6.714 9.259 1.00 3.71 ? 501 MET A N 1 ATOM 3988 C CA . MET A 1 501 ? -17.020 -6.476 7.819 1.00 3.27 ? 501 MET A CA 1 ATOM 3989 C C . MET A 1 501 ? -18.397 -6.288 7.208 1.00 2.27 ? 501 MET A C 1 ATOM 3990 O O . MET A 1 501 ? -19.394 -6.855 7.647 1.00 2.00 ? 501 MET A O 1 ATOM 3991 C CB . MET A 1 501 ? -16.280 -7.562 7.043 1.00 5.10 ? 501 MET A CB 1 ATOM 3992 C CG . MET A 1 501 ? -14.774 -7.426 7.172 1.00 8.97 ? 501 MET A CG 1 ATOM 3993 S SD . MET A 1 501 ? -13.871 -8.997 7.185 1.00 15.50 ? 501 MET A SD 1 ATOM 3994 C CE . MET A 1 501 ? -12.621 -8.697 5.874 1.00 13.35 ? 501 MET A CE 1 ATOM 3995 N N . VAL A 1 502 ? -18.422 -5.474 6.163 1.00 3.20 ? 502 VAL A N 1 ATOM 3996 C CA . VAL A 1 502 ? -19.645 -5.178 5.443 1.00 5.01 ? 502 VAL A CA 1 ATOM 3997 C C . VAL A 1 502 ? -19.935 -6.319 4.474 1.00 5.81 ? 502 VAL A C 1 ATOM 3998 O O . VAL A 1 502 ? -19.097 -7.207 4.286 1.00 5.77 ? 502 VAL A O 1 ATOM 3999 C CB . VAL A 1 502 ? -19.515 -3.845 4.662 1.00 2.00 ? 502 VAL A CB 1 ATOM 4000 C CG1 . VAL A 1 502 ? -19.128 -2.726 5.612 1.00 2.00 ? 502 VAL A CG1 1 ATOM 4001 C CG2 . VAL A 1 502 ? -18.488 -3.977 3.557 1.00 2.00 ? 502 VAL A CG2 1 ATOM 4002 N N . GLU A 1 503 ? -21.121 -6.286 3.866 1.00 8.72 ? 503 GLU A N 1 ATOM 4003 C CA . GLU A 1 503 ? -21.544 -7.317 2.918 1.00 10.66 ? 503 GLU A CA 1 ATOM 4004 C C . GLU A 1 503 ? -20.600 -7.367 1.713 1.00 9.50 ? 503 GLU A C 1 ATOM 4005 O O . GLU A 1 503 ? -20.148 -6.335 1.219 1.00 7.17 ? 503 GLU A O 1 ATOM 4006 C CB . GLU A 1 503 ? -22.981 -7.049 2.447 1.00 14.66 ? 503 GLU A CB 1 ATOM 4007 C CG . GLU A 1 503 ? -23.780 -8.308 2.078 1.00 20.69 ? 503 GLU A CG 1 ATOM 4008 C CD . GLU A 1 503 ? -24.960 -8.021 1.137 1.00 24.69 ? 503 GLU A CD 1 ATOM 4009 O OE1 . GLU A 1 503 ? -25.725 -7.061 1.396 1.00 26.76 ? 503 GLU A OE1 1 ATOM 4010 O OE2 . GLU A 1 503 ? -25.126 -8.763 0.138 1.00 26.47 ? 503 GLU A OE2 1 ATOM 4011 N N . ARG A 1 504 ? -20.285 -8.587 1.294 1.00 9.08 ? 504 ARG A N 1 ATOM 4012 C CA . ARG A 1 504 ? -19.430 -8.874 0.167 1.00 9.13 ? 504 ARG A CA 1 ATOM 4013 C C . ARG A 1 504 ? -18.195 -7.996 -0.032 1.00 8.37 ? 504 ARG A C 1 ATOM 4014 O O . ARG A 1 504 ? -17.682 -7.870 -1.133 1.00 7.97 ? 504 ARG A O 1 ATOM 4015 C CB . ARG A 1 504 ? -20.319 -8.854 -1.080 1.00 13.17 ? 504 ARG A CB 1 ATOM 4016 C CG . ARG A 1 504 ? -21.000 -10.167 -1.390 1.00 23.19 ? 504 ARG A CG 1 ATOM 4017 C CD . ARG A 1 504 ? -20.318 -10.736 -2.604 1.00 29.95 ? 504 ARG A CD 1 ATOM 4018 N NE . ARG A 1 504 ? -21.156 -11.609 -3.399 1.00 37.48 ? 504 ARG A NE 1 ATOM 4019 C CZ . ARG A 1 504 ? -21.276 -12.918 -3.167 1.00 41.73 ? 504 ARG A CZ 1 ATOM 4020 N NH1 . ARG A 1 504 ? -20.636 -13.489 -2.145 1.00 43.49 ? 504 ARG A NH1 1 ATOM 4021 N NH2 . ARG A 1 504 ? -22.031 -13.668 -3.967 1.00 44.87 ? 504 ARG A NH2 1 ATOM 4022 N N . GLY A 1 505 ? -17.738 -7.386 1.063 1.00 6.65 ? 505 GLY A N 1 ATOM 4023 C CA . GLY A 1 505 ? -16.554 -6.538 1.022 1.00 4.89 ? 505 GLY A CA 1 ATOM 4024 C C . GLY A 1 505 ? -15.542 -6.989 2.062 1.00 4.92 ? 505 GLY A C 1 ATOM 4025 O O . GLY A 1 505 ? -15.714 -8.044 2.668 1.00 5.99 ? 505 GLY A O 1 ATOM 4026 N N . ARG A 1 506 ? -14.493 -6.211 2.297 1.00 3.81 ? 506 ARG A N 1 ATOM 4027 C CA . ARG A 1 506 ? -13.510 -6.633 3.282 1.00 2.00 ? 506 ARG A CA 1 ATOM 4028 C C . ARG A 1 506 ? -13.156 -5.601 4.330 1.00 2.00 ? 506 ARG A C 1 ATOM 4029 O O . ARG A 1 506 ? -12.126 -5.721 4.991 1.00 2.00 ? 506 ARG A O 1 ATOM 4030 C CB . ARG A 1 506 ? -12.245 -7.122 2.586 1.00 2.04 ? 506 ARG A CB 1 ATOM 4031 C CG . ARG A 1 506 ? -12.447 -8.408 1.817 1.00 2.71 ? 506 ARG A CG 1 ATOM 4032 C CD . ARG A 1 506 ? -13.077 -9.462 2.707 1.00 4.96 ? 506 ARG A CD 1 ATOM 4033 N NE . ARG A 1 506 ? -12.829 -10.816 2.219 1.00 7.68 ? 506 ARG A NE 1 ATOM 4034 C CZ . ARG A 1 506 ? -13.761 -11.637 1.741 1.00 7.87 ? 506 ARG A CZ 1 ATOM 4035 N NH1 . ARG A 1 506 ? -15.027 -11.257 1.680 1.00 8.21 ? 506 ARG A NH1 1 ATOM 4036 N NH2 . ARG A 1 506 ? -13.425 -12.848 1.320 1.00 9.30 ? 506 ARG A NH2 1 ATOM 4037 N N . VAL A 1 507 ? -14.006 -4.590 4.489 1.00 2.00 ? 507 VAL A N 1 ATOM 4038 C CA . VAL A 1 507 ? -13.772 -3.568 5.499 1.00 2.00 ? 507 VAL A CA 1 ATOM 4039 C C . VAL A 1 507 ? -15.077 -3.161 6.174 1.00 2.00 ? 507 VAL A C 1 ATOM 4040 O O . VAL A 1 507 ? -16.155 -3.344 5.620 1.00 2.00 ? 507 VAL A O 1 ATOM 4041 C CB . VAL A 1 507 ? -13.113 -2.333 4.900 1.00 2.00 ? 507 VAL A CB 1 ATOM 4042 C CG1 . VAL A 1 507 ? -12.069 -2.760 3.895 1.00 2.00 ? 507 VAL A CG1 1 ATOM 4043 C CG2 . VAL A 1 507 ? -14.154 -1.436 4.270 1.00 2.00 ? 507 VAL A CG2 1 ATOM 4044 N N . GLY A 1 508 ? -14.969 -2.605 7.374 1.00 2.00 ? 508 GLY A N 1 ATOM 4045 C CA . GLY A 1 508 ? -16.149 -2.205 8.116 1.00 2.27 ? 508 GLY A CA 1 ATOM 4046 C C . GLY A 1 508 ? -16.811 -0.949 7.598 1.00 2.50 ? 508 GLY A C 1 ATOM 4047 O O . GLY A 1 508 ? -16.262 -0.284 6.715 1.00 2.13 ? 508 GLY A O 1 ATOM 4048 N N . PRO A 1 509 ? -17.997 -0.592 8.132 1.00 2.54 ? 509 PRO A N 1 ATOM 4049 C CA . PRO A 1 509 ? -18.701 0.608 7.687 1.00 2.00 ? 509 PRO A CA 1 ATOM 4050 C C . PRO A 1 509 ? -17.841 1.870 7.721 1.00 2.00 ? 509 PRO A C 1 ATOM 4051 O O . PRO A 1 509 ? -17.917 2.677 6.803 1.00 2.00 ? 509 PRO A O 1 ATOM 4052 C CB . PRO A 1 509 ? -19.911 0.665 8.626 1.00 2.00 ? 509 PRO A CB 1 ATOM 4053 C CG . PRO A 1 509 ? -19.465 -0.070 9.835 1.00 2.00 ? 509 PRO A CG 1 ATOM 4054 C CD . PRO A 1 509 ? -18.732 -1.230 9.238 1.00 2.00 ? 509 PRO A CD 1 ATOM 4055 N N . LEU A 1 510 ? -17.020 2.038 8.759 1.00 2.00 ? 510 LEU A N 1 ATOM 4056 C CA . LEU A 1 510 ? -16.163 3.217 8.848 1.00 2.00 ? 510 LEU A CA 1 ATOM 4057 C C . LEU A 1 510 ? -15.172 3.261 7.689 1.00 3.25 ? 510 LEU A C 1 ATOM 4058 O O . LEU A 1 510 ? -15.275 4.130 6.827 1.00 4.02 ? 510 LEU A O 1 ATOM 4059 C CB . LEU A 1 510 ? -15.387 3.247 10.161 1.00 2.50 ? 510 LEU A CB 1 ATOM 4060 C CG . LEU A 1 510 ? -14.641 4.572 10.395 1.00 3.53 ? 510 LEU A CG 1 ATOM 4061 C CD1 . LEU A 1 510 ? -15.657 5.676 10.625 1.00 3.37 ? 510 LEU A CD1 1 ATOM 4062 C CD2 . LEU A 1 510 ? -13.709 4.478 11.597 1.00 3.45 ? 510 LEU A CD2 1 ATOM 4063 N N . LEU A 1 511 ? -14.213 2.334 7.663 1.00 3.26 ? 511 LEU A N 1 ATOM 4064 C CA . LEU A 1 511 ? -13.220 2.296 6.583 1.00 2.00 ? 511 LEU A CA 1 ATOM 4065 C C . LEU A 1 511 ? -13.877 2.392 5.220 1.00 2.00 ? 511 LEU A C 1 ATOM 4066 O O . LEU A 1 511 ? -13.367 3.055 4.325 1.00 2.00 ? 511 LEU A O 1 ATOM 4067 C CB . LEU A 1 511 ? -12.382 1.011 6.630 1.00 2.00 ? 511 LEU A CB 1 ATOM 4068 C CG . LEU A 1 511 ? -11.168 0.938 7.568 1.00 2.00 ? 511 LEU A CG 1 ATOM 4069 C CD1 . LEU A 1 511 ? -10.334 2.200 7.408 1.00 2.00 ? 511 LEU A CD1 1 ATOM 4070 C CD2 . LEU A 1 511 ? -11.612 0.780 9.012 1.00 2.00 ? 511 LEU A CD2 1 ATOM 4071 N N . ALA A 1 512 ? -15.008 1.720 5.062 1.00 2.00 ? 512 ALA A N 1 ATOM 4072 C CA . ALA A 1 512 ? -15.717 1.751 3.796 1.00 2.00 ? 512 ALA A CA 1 ATOM 4073 C C . ALA A 1 512 ? -15.895 3.200 3.364 1.00 2.02 ? 512 ALA A C 1 ATOM 4074 O O . ALA A 1 512 ? -15.712 3.544 2.198 1.00 2.58 ? 512 ALA A O 1 ATOM 4075 C CB . ALA A 1 512 ? -17.070 1.073 3.937 1.00 2.00 ? 512 ALA A CB 1 ATOM 4076 N N . CYS A 1 513 ? -16.245 4.047 4.320 1.00 2.00 ? 513 CYS A N 1 ATOM 4077 C CA . CYS A 1 513 ? -16.453 5.461 4.060 1.00 2.00 ? 513 CYS A CA 1 ATOM 4078 C C . CYS A 1 513 ? -15.164 6.128 3.601 1.00 2.00 ? 513 CYS A C 1 ATOM 4079 O O . CYS A 1 513 ? -15.049 6.531 2.443 1.00 2.00 ? 513 CYS A O 1 ATOM 4080 C CB . CYS A 1 513 ? -16.976 6.125 5.332 1.00 2.00 ? 513 CYS A CB 1 ATOM 4081 S SG . CYS A 1 513 ? -16.807 7.932 5.462 1.00 2.00 ? 513 CYS A SG 1 ATOM 4082 N N . LEU A 1 514 ? -14.207 6.224 4.525 1.00 3.57 ? 514 LEU A N 1 ATOM 4083 C CA . LEU A 1 514 ? -12.892 6.830 4.306 1.00 2.00 ? 514 LEU A CA 1 ATOM 4084 C C . LEU A 1 514 ? -12.293 6.432 2.970 1.00 2.00 ? 514 LEU A C 1 ATOM 4085 O O . LEU A 1 514 ? -11.921 7.279 2.159 1.00 2.00 ? 514 LEU A O 1 ATOM 4086 C CB . LEU A 1 514 ? -11.954 6.431 5.426 1.00 2.00 ? 514 LEU A CB 1 ATOM 4087 C CG . LEU A 1 514 ? -12.483 6.677 6.830 1.00 2.00 ? 514 LEU A CG 1 ATOM 4088 C CD1 . LEU A 1 514 ? -11.818 5.742 7.818 1.00 2.00 ? 514 LEU A CD1 1 ATOM 4089 C CD2 . LEU A 1 514 ? -12.267 8.121 7.253 1.00 2.00 ? 514 LEU A CD2 1 ATOM 4090 N N . LEU A 1 515 ? -12.218 5.131 2.753 1.00 2.00 ? 515 LEU A N 1 ATOM 4091 C CA . LEU A 1 515 ? -11.647 4.601 1.508 1.00 2.00 ? 515 LEU A CA 1 ATOM 4092 C C . LEU A 1 515 ? -12.489 4.854 0.302 1.00 2.00 ? 515 LEU A C 1 ATOM 4093 O O . LEU A 1 515 ? -11.966 4.967 -0.809 1.00 2.18 ? 515 LEU A O 1 ATOM 4094 C CB . LEU A 1 515 ? -11.562 3.106 1.503 1.00 2.67 ? 515 LEU A CB 1 ATOM 4095 C CG . LEU A 1 515 ? -10.696 2.477 2.563 1.00 2.00 ? 515 LEU A CG 1 ATOM 4096 C CD1 . LEU A 1 515 ? -10.542 0.975 2.323 1.00 2.00 ? 515 LEU A CD1 1 ATOM 4097 C CD2 . LEU A 1 515 ? -9.328 3.131 2.595 1.00 2.00 ? 515 LEU A CD2 1 ATOM 4098 N N . GLY A 1 516 ? -13.779 4.916 0.456 1.00 2.00 ? 516 GLY A N 1 ATOM 4099 C CA . GLY A 1 516 ? -14.635 5.140 -0.684 1.00 2.20 ? 516 GLY A CA 1 ATOM 4100 C C . GLY A 1 516 ? -14.474 6.581 -1.145 1.00 2.00 ? 516 GLY A C 1 ATOM 4101 O O . GLY A 1 516 ? -14.304 6.857 -2.344 1.00 2.11 ? 516 GLY A O 1 ATOM 4102 N N . ARG A 1 517 ? -14.550 7.465 -0.191 1.00 2.00 ? 517 ARG A N 1 ATOM 4103 C CA . ARG A 1 517 ? -14.430 8.885 -0.472 1.00 3.16 ? 517 ARG A CA 1 ATOM 4104 C C . ARG A 1 517 ? -13.111 9.227 -1.141 1.00 2.69 ? 517 ARG A C 1 ATOM 4105 O O . ARG A 1 517 ? -13.091 9.934 -2.147 1.00 3.48 ? 517 ARG A O 1 ATOM 4106 C CB . ARG A 1 517 ? -14.551 9.710 0.809 1.00 6.91 ? 517 ARG A CB 1 ATOM 4107 C CG . ARG A 1 517 ? -15.925 9.670 1.474 1.00 11.12 ? 517 ARG A CG 1 ATOM 4108 C CD . ARG A 1 517 ? -16.148 10.918 2.321 1.00 12.41 ? 517 ARG A CD 1 ATOM 4109 N NE . ARG A 1 517 ? -17.401 10.867 3.068 1.00 15.90 ? 517 ARG A NE 1 ATOM 4110 C CZ . ARG A 1 517 ? -17.911 11.901 3.731 1.00 16.86 ? 517 ARG A CZ 1 ATOM 4111 N NH1 . ARG A 1 517 ? -17.271 13.064 3.731 1.00 18.42 ? 517 ARG A NH1 1 ATOM 4112 N NH2 . ARG A 1 517 ? -19.055 11.776 4.397 1.00 17.48 ? 517 ARG A NH2 1 ATOM 4113 N N . GLN A 1 518 ? -12.011 8.731 -0.578 1.00 3.21 ? 518 GLN A N 1 ATOM 4114 C CA . GLN A 1 518 ? -10.681 9.012 -1.119 1.00 2.10 ? 518 GLN A CA 1 ATOM 4115 C C . GLN A 1 518 ? -10.530 8.572 -2.555 1.00 2.00 ? 518 GLN A C 1 ATOM 4116 O O . GLN A 1 518 ? -10.123 9.348 -3.410 1.00 2.00 ? 518 GLN A O 1 ATOM 4117 C CB . GLN A 1 518 ? -9.592 8.328 -0.291 1.00 2.16 ? 518 GLN A CB 1 ATOM 4118 C CG . GLN A 1 518 ? -8.180 8.699 -0.715 1.00 2.00 ? 518 GLN A CG 1 ATOM 4119 C CD . GLN A 1 518 ? -7.829 10.131 -0.377 1.00 2.00 ? 518 GLN A CD 1 ATOM 4120 O OE1 . GLN A 1 518 ? -7.241 10.409 0.662 1.00 2.00 ? 518 GLN A OE1 1 ATOM 4121 N NE2 . GLN A 1 518 ? -8.203 11.051 -1.251 1.00 2.48 ? 518 GLN A NE2 1 ATOM 4122 N N . PHE A 1 519 ? -10.862 7.321 -2.823 1.00 2.00 ? 519 PHE A N 1 ATOM 4123 C CA . PHE A 1 519 ? -10.712 6.815 -4.167 1.00 2.00 ? 519 PHE A CA 1 ATOM 4124 C C . PHE A 1 519 ? -11.539 7.524 -5.206 1.00 2.00 ? 519 PHE A C 1 ATOM 4125 O O . PHE A 1 519 ? -11.052 7.822 -6.297 1.00 2.67 ? 519 PHE A O 1 ATOM 4126 C CB . PHE A 1 519 ? -10.988 5.326 -4.190 1.00 2.58 ? 519 PHE A CB 1 ATOM 4127 C CG . PHE A 1 519 ? -9.791 4.510 -3.838 1.00 2.61 ? 519 PHE A CG 1 ATOM 4128 C CD1 . PHE A 1 519 ? -8.668 4.538 -4.652 1.00 2.00 ? 519 PHE A CD1 1 ATOM 4129 C CD2 . PHE A 1 519 ? -9.772 3.737 -2.683 1.00 2.22 ? 519 PHE A CD2 1 ATOM 4130 C CE1 . PHE A 1 519 ? -7.543 3.810 -4.326 1.00 2.00 ? 519 PHE A CE1 1 ATOM 4131 C CE2 . PHE A 1 519 ? -8.650 3.005 -2.348 1.00 3.27 ? 519 PHE A CE2 1 ATOM 4132 C CZ . PHE A 1 519 ? -7.527 3.040 -3.174 1.00 2.50 ? 519 PHE A CZ 1 ATOM 4133 N N . GLN A 1 520 ? -12.793 7.792 -4.881 1.00 2.73 ? 520 GLN A N 1 ATOM 4134 C CA . GLN A 1 520 ? -13.651 8.497 -5.817 1.00 3.69 ? 520 GLN A CA 1 ATOM 4135 C C . GLN A 1 520 ? -12.952 9.794 -6.220 1.00 4.20 ? 520 GLN A C 1 ATOM 4136 O O . GLN A 1 520 ? -12.841 10.125 -7.403 1.00 5.07 ? 520 GLN A O 1 ATOM 4137 C CB . GLN A 1 520 ? -14.982 8.815 -5.150 1.00 3.79 ? 520 GLN A CB 1 ATOM 4138 C CG . GLN A 1 520 ? -15.469 10.210 -5.408 1.00 4.96 ? 520 GLN A CG 1 ATOM 4139 C CD . GLN A 1 520 ? -16.440 10.656 -4.354 1.00 7.91 ? 520 GLN A CD 1 ATOM 4140 O OE1 . GLN A 1 520 ? -16.775 11.833 -4.268 1.00 10.37 ? 520 GLN A OE1 1 ATOM 4141 N NE2 . GLN A 1 520 ? -16.904 9.714 -3.533 1.00 8.27 ? 520 GLN A NE2 1 ATOM 4142 N N . GLN A 1 521 ? -12.458 10.504 -5.214 1.00 3.49 ? 521 GLN A N 1 ATOM 4143 C CA . GLN A 1 521 ? -11.774 11.777 -5.395 1.00 2.83 ? 521 GLN A CA 1 ATOM 4144 C C . GLN A 1 521 ? -10.557 11.849 -6.311 1.00 2.55 ? 521 GLN A C 1 ATOM 4145 O O . GLN A 1 521 ? -10.450 12.784 -7.099 1.00 2.44 ? 521 GLN A O 1 ATOM 4146 C CB . GLN A 1 521 ? -11.376 12.321 -4.040 1.00 4.06 ? 521 GLN A CB 1 ATOM 4147 C CG . GLN A 1 521 ? -11.939 13.669 -3.777 1.00 7.35 ? 521 GLN A CG 1 ATOM 4148 C CD . GLN A 1 521 ? -11.942 13.983 -2.312 1.00 9.56 ? 521 GLN A CD 1 ATOM 4149 O OE1 . GLN A 1 521 ? -10.912 14.356 -1.741 1.00 12.36 ? 521 GLN A OE1 1 ATOM 4150 N NE2 . GLN A 1 521 ? -13.100 13.813 -1.676 1.00 9.85 ? 521 GLN A NE2 1 ATOM 4151 N N . ILE A 1 522 ? -9.629 10.896 -6.192 1.00 3.27 ? 522 ILE A N 1 ATOM 4152 C CA . ILE A 1 522 ? -8.422 10.896 -7.028 1.00 2.40 ? 522 ILE A CA 1 ATOM 4153 C C . ILE A 1 522 ? -8.787 10.485 -8.452 1.00 2.00 ? 522 ILE A C 1 ATOM 4154 O O . ILE A 1 522 ? -7.986 10.598 -9.384 1.00 2.00 ? 522 ILE A O 1 ATOM 4155 C CB . ILE A 1 522 ? -7.326 9.938 -6.468 1.00 2.00 ? 522 ILE A CB 1 ATOM 4156 C CG1 . ILE A 1 522 ? -7.698 8.480 -6.714 1.00 2.33 ? 522 ILE A CG1 1 ATOM 4157 C CG2 . ILE A 1 522 ? -7.161 10.142 -4.975 1.00 2.99 ? 522 ILE A CG2 1 ATOM 4158 C CD1 . ILE A 1 522 ? -6.745 7.778 -7.659 1.00 3.60 ? 522 ILE A CD1 1 ATOM 4159 N N . ARG A 1 523 ? -10.020 10.019 -8.600 1.00 2.16 ? 523 ARG A N 1 ATOM 4160 C CA . ARG A 1 523 ? -10.539 9.599 -9.880 1.00 2.88 ? 523 ARG A CA 1 ATOM 4161 C C . ARG A 1 523 ? -11.356 10.723 -10.519 1.00 4.27 ? 523 ARG A C 1 ATOM 4162 O O . ARG A 1 523 ? -11.356 10.873 -11.736 1.00 7.40 ? 523 ARG A O 1 ATOM 4163 C CB . ARG A 1 523 ? -11.391 8.346 -9.694 1.00 2.00 ? 523 ARG A CB 1 ATOM 4164 C CG . ARG A 1 523 ? -12.275 7.982 -10.882 1.00 2.07 ? 523 ARG A CG 1 ATOM 4165 C CD . ARG A 1 523 ? -13.699 8.496 -10.680 1.00 2.87 ? 523 ARG A CD 1 ATOM 4166 N NE . ARG A 1 523 ? -14.700 7.482 -11.001 1.00 2.00 ? 523 ARG A NE 1 ATOM 4167 C CZ . ARG A 1 523 ? -15.968 7.527 -10.606 1.00 2.00 ? 523 ARG A CZ 1 ATOM 4168 N NH1 . ARG A 1 523 ? -16.414 8.540 -9.868 1.00 2.00 ? 523 ARG A NH1 1 ATOM 4169 N NH2 . ARG A 1 523 ? -16.788 6.543 -10.940 1.00 2.00 ? 523 ARG A NH2 1 ATOM 4170 N N . ASP A 1 524 ? -12.047 11.525 -9.716 1.00 3.48 ? 524 ASP A N 1 ATOM 4171 C CA . ASP A 1 524 ? -12.836 12.607 -10.293 1.00 2.00 ? 524 ASP A CA 1 ATOM 4172 C C . ASP A 1 524 ? -12.059 13.908 -10.475 1.00 2.00 ? 524 ASP A C 1 ATOM 4173 O O . ASP A 1 524 ? -12.514 14.813 -11.173 1.00 2.00 ? 524 ASP A O 1 ATOM 4174 C CB . ASP A 1 524 ? -14.092 12.867 -9.453 1.00 2.00 ? 524 ASP A CB 1 ATOM 4175 C CG . ASP A 1 524 ? -15.118 11.758 -9.589 1.00 2.00 ? 524 ASP A CG 1 ATOM 4176 O OD1 . ASP A 1 524 ? -15.092 11.087 -10.630 1.00 2.22 ? 524 ASP A OD1 1 ATOM 4177 O OD2 . ASP A 1 524 ? -15.956 11.556 -8.682 1.00 2.00 ? 524 ASP A OD2 1 ATOM 4178 N N . GLY A 1 525 ? -10.884 14.001 -9.864 1.00 2.00 ? 525 GLY A N 1 ATOM 4179 C CA . GLY A 1 525 ? -10.104 15.221 -9.978 1.00 2.00 ? 525 GLY A CA 1 ATOM 4180 C C . GLY A 1 525 ? -8.835 15.082 -10.796 1.00 2.68 ? 525 GLY A C 1 ATOM 4181 O O . GLY A 1 525 ? -8.063 16.039 -10.932 1.00 2.63 ? 525 GLY A O 1 ATOM 4182 N N . ASP A 1 526 ? -8.622 13.894 -11.351 1.00 2.92 ? 526 ASP A N 1 ATOM 4183 C CA . ASP A 1 526 ? -7.432 13.630 -12.146 1.00 2.41 ? 526 ASP A CA 1 ATOM 4184 C C . ASP A 1 526 ? -7.725 13.897 -13.607 1.00 2.00 ? 526 ASP A C 1 ATOM 4185 O O . ASP A 1 526 ? -8.364 13.092 -14.273 1.00 2.00 ? 526 ASP A O 1 ATOM 4186 C CB . ASP A 1 526 ? -6.986 12.181 -11.940 1.00 3.69 ? 526 ASP A CB 1 ATOM 4187 C CG . ASP A 1 526 ? -5.823 11.804 -12.820 1.00 4.94 ? 526 ASP A CG 1 ATOM 4188 O OD1 . ASP A 1 526 ? -4.847 12.577 -12.872 1.00 7.27 ? 526 ASP A OD1 1 ATOM 4189 O OD2 . ASP A 1 526 ? -5.882 10.735 -13.458 1.00 5.49 ? 526 ASP A OD2 1 ATOM 4190 N N . ARG A 1 527 ? -7.247 15.034 -14.097 1.00 2.00 ? 527 ARG A N 1 ATOM 4191 C CA . ARG A 1 527 ? -7.477 15.445 -15.483 1.00 3.24 ? 527 ARG A CA 1 ATOM 4192 C C . ARG A 1 527 ? -7.110 14.382 -16.493 1.00 2.09 ? 527 ARG A C 1 ATOM 4193 O O . ARG A 1 527 ? -7.598 14.405 -17.625 1.00 2.00 ? 527 ARG A O 1 ATOM 4194 C CB . ARG A 1 527 ? -6.695 16.728 -15.802 1.00 2.98 ? 527 ARG A CB 1 ATOM 4195 C CG . ARG A 1 527 ? -6.904 17.269 -17.211 1.00 2.00 ? 527 ARG A CG 1 ATOM 4196 C CD . ARG A 1 527 ? -6.432 18.710 -17.289 1.00 2.00 ? 527 ARG A CD 1 ATOM 4197 N NE . ARG A 1 527 ? -4.980 18.818 -17.213 1.00 2.00 ? 527 ARG A NE 1 ATOM 4198 C CZ . ARG A 1 527 ? -4.179 18.723 -18.267 1.00 2.00 ? 527 ARG A CZ 1 ATOM 4199 N NH1 . ARG A 1 527 ? -4.697 18.523 -19.467 1.00 2.00 ? 527 ARG A NH1 1 ATOM 4200 N NH2 . ARG A 1 527 ? -2.864 18.822 -18.127 1.00 2.00 ? 527 ARG A NH2 1 ATOM 4201 N N . PHE A 1 528 ? -6.255 13.449 -16.082 1.00 2.19 ? 528 PHE A N 1 ATOM 4202 C CA . PHE A 1 528 ? -5.809 12.389 -16.981 1.00 3.68 ? 528 PHE A CA 1 ATOM 4203 C C . PHE A 1 528 ? -6.463 11.027 -16.794 1.00 2.82 ? 528 PHE A C 1 ATOM 4204 O O . PHE A 1 528 ? -6.079 10.065 -17.467 1.00 2.00 ? 528 PHE A O 1 ATOM 4205 C CB . PHE A 1 528 ? -4.288 12.227 -16.908 1.00 2.85 ? 528 PHE A CB 1 ATOM 4206 C CG . PHE A 1 528 ? -3.528 13.361 -17.533 1.00 2.00 ? 528 PHE A CG 1 ATOM 4207 C CD1 . PHE A 1 528 ? -3.210 14.492 -16.797 1.00 3.37 ? 528 PHE A CD1 1 ATOM 4208 C CD2 . PHE A 1 528 ? -3.141 13.301 -18.864 1.00 2.00 ? 528 PHE A CD2 1 ATOM 4209 C CE1 . PHE A 1 528 ? -2.515 15.547 -17.381 1.00 4.17 ? 528 PHE A CE1 1 ATOM 4210 C CE2 . PHE A 1 528 ? -2.448 14.349 -19.456 1.00 2.59 ? 528 PHE A CE2 1 ATOM 4211 C CZ . PHE A 1 528 ? -2.133 15.473 -18.716 1.00 3.55 ? 528 PHE A CZ 1 ATOM 4212 N N . TRP A 1 529 ? -7.435 10.936 -15.887 1.00 2.28 ? 529 TRP A N 1 ATOM 4213 C CA . TRP A 1 529 ? -8.137 9.674 -15.682 1.00 2.50 ? 529 TRP A CA 1 ATOM 4214 C C . TRP A 1 529 ? -8.483 9.193 -17.094 1.00 2.78 ? 529 TRP A C 1 ATOM 4215 O O . TRP A 1 529 ? -8.874 9.990 -17.939 1.00 3.79 ? 529 TRP A O 1 ATOM 4216 C CB . TRP A 1 529 ? -9.399 9.897 -14.850 1.00 2.00 ? 529 TRP A CB 1 ATOM 4217 C CG . TRP A 1 529 ? -10.129 8.638 -14.569 1.00 2.00 ? 529 TRP A CG 1 ATOM 4218 C CD1 . TRP A 1 529 ? -11.182 8.131 -15.267 1.00 2.93 ? 529 TRP A CD1 1 ATOM 4219 C CD2 . TRP A 1 529 ? -9.812 7.670 -13.563 1.00 2.00 ? 529 TRP A CD2 1 ATOM 4220 N NE1 . TRP A 1 529 ? -11.544 6.904 -14.764 1.00 3.24 ? 529 TRP A NE1 1 ATOM 4221 C CE2 . TRP A 1 529 ? -10.717 6.597 -13.715 1.00 2.17 ? 529 TRP A CE2 1 ATOM 4222 C CE3 . TRP A 1 529 ? -8.850 7.603 -12.548 1.00 2.11 ? 529 TRP A CE3 1 ATOM 4223 C CZ2 . TRP A 1 529 ? -10.688 5.468 -12.890 1.00 2.00 ? 529 TRP A CZ2 1 ATOM 4224 C CZ3 . TRP A 1 529 ? -8.823 6.477 -11.727 1.00 2.00 ? 529 TRP A CZ3 1 ATOM 4225 C CH2 . TRP A 1 529 ? -9.736 5.429 -11.905 1.00 2.00 ? 529 TRP A CH2 1 ATOM 4226 N N . TRP A 1 530 ? -8.364 7.903 -17.363 1.00 3.29 ? 530 TRP A N 1 ATOM 4227 C CA . TRP A 1 530 ? -8.581 7.392 -18.742 1.00 4.42 ? 530 TRP A CA 1 ATOM 4228 C C . TRP A 1 530 ? -9.988 7.554 -19.311 1.00 3.47 ? 530 TRP A C 1 ATOM 4229 O O . TRP A 1 530 ? -10.124 7.948 -20.475 1.00 2.90 ? 530 TRP A O 1 ATOM 4230 C CB . TRP A 1 530 ? -8.137 5.922 -18.788 1.00 3.51 ? 530 TRP A CB 1 ATOM 4231 C CG . TRP A 1 530 ? -9.055 5.032 -18.011 1.00 2.37 ? 530 TRP A CG 1 ATOM 4232 C CD1 . TRP A 1 530 ? -9.142 4.942 -16.658 1.00 2.86 ? 530 TRP A CD1 1 ATOM 4233 C CD2 . TRP A 1 530 ? -10.024 4.130 -18.540 1.00 2.30 ? 530 TRP A CD2 1 ATOM 4234 N NE1 . TRP A 1 530 ? -10.113 4.034 -16.306 1.00 2.79 ? 530 TRP A NE1 1 ATOM 4235 C CE2 . TRP A 1 530 ? -10.671 3.523 -17.446 1.00 2.00 ? 530 TRP A CE2 1 ATOM 4236 C CE3 . TRP A 1 530 ? -10.413 3.778 -19.836 1.00 2.20 ? 530 TRP A CE3 1 ATOM 4237 C CZ2 . TRP A 1 530 ? -11.683 2.583 -17.604 1.00 2.00 ? 530 TRP A CZ2 1 ATOM 4238 C CZ3 . TRP A 1 530 ? -11.421 2.842 -19.994 1.00 2.71 ? 530 TRP A CZ3 1 ATOM 4239 C CH2 . TRP A 1 530 ? -12.046 2.255 -18.882 1.00 2.29 ? 530 TRP A CH2 1 ATOM 4240 N N . GLU A 1 531 ? -11.028 7.242 -18.543 1.00 4.04 ? 531 GLU A N 1 ATOM 4241 C CA . GLU A 1 531 ? -12.361 7.331 -19.118 1.00 4.87 ? 531 GLU A CA 1 ATOM 4242 C C . GLU A 1 531 ? -12.643 8.734 -19.621 1.00 4.64 ? 531 GLU A C 1 ATOM 4243 O O . GLU A 1 531 ? -13.549 8.941 -20.447 1.00 5.89 ? 531 GLU A O 1 ATOM 4244 C CB . GLU A 1 531 ? -13.395 6.825 -18.128 1.00 5.81 ? 531 GLU A CB 1 ATOM 4245 C CG . GLU A 1 531 ? -13.744 5.355 -18.302 1.00 8.42 ? 531 GLU A CG 1 ATOM 4246 C CD . GLU A 1 531 ? -14.711 4.861 -17.259 1.00 12.02 ? 531 GLU A CD 1 ATOM 4247 O OE1 . GLU A 1 531 ? -14.504 5.164 -16.064 1.00 13.51 ? 531 GLU A OE1 1 ATOM 4248 O OE2 . GLU A 1 531 ? -15.697 4.177 -17.620 1.00 13.97 ? 531 GLU A OE2 1 ATOM 4249 N N . ASN A 1 532 ? -11.865 9.685 -19.125 1.00 4.12 ? 532 ASN A N 1 ATOM 4250 C CA . ASN A 1 532 ? -12.012 11.088 -19.488 1.00 3.62 ? 532 ASN A CA 1 ATOM 4251 C C . ASN A 1 532 ? -11.752 11.324 -20.947 1.00 4.08 ? 532 ASN A C 1 ATOM 4252 O O . ASN A 1 532 ? -10.764 10.799 -21.490 1.00 4.73 ? 532 ASN A O 1 ATOM 4253 C CB . ASN A 1 532 ? -11.051 11.917 -18.656 1.00 4.46 ? 532 ASN A CB 1 ATOM 4254 C CG . ASN A 1 532 ? -11.320 13.376 -18.769 1.00 6.15 ? 532 ASN A CG 1 ATOM 4255 O OD1 . ASN A 1 532 ? -12.454 13.820 -18.580 1.00 8.22 ? 532 ASN A OD1 1 ATOM 4256 N ND2 . ASN A 1 532 ? -10.283 14.148 -19.074 1.00 7.24 ? 532 ASN A ND2 1 ATOM 4257 N N . PRO A 1 533 ? -12.581 12.109 -21.636 1.00 3.93 ? 533 PRO A N 1 ATOM 4258 C CA . PRO A 1 533 ? -12.395 12.349 -23.070 1.00 4.35 ? 533 PRO A CA 1 ATOM 4259 C C . PRO A 1 533 ? -11.149 13.172 -23.368 1.00 6.24 ? 533 PRO A C 1 ATOM 4260 O O . PRO A 1 533 ? -10.802 14.080 -22.616 1.00 7.84 ? 533 PRO A O 1 ATOM 4261 C CB . PRO A 1 533 ? -13.680 13.063 -23.462 1.00 3.27 ? 533 PRO A CB 1 ATOM 4262 C CG . PRO A 1 533 ? -14.684 12.506 -22.468 1.00 2.94 ? 533 PRO A CG 1 ATOM 4263 C CD . PRO A 1 533 ? -13.903 12.580 -21.194 1.00 2.74 ? 533 PRO A CD 1 ATOM 4264 N N . GLY A 1 534 ? -10.477 12.853 -24.469 1.00 7.19 ? 534 GLY A N 1 ATOM 4265 C CA . GLY A 1 534 ? -9.273 13.579 -24.828 1.00 8.66 ? 534 GLY A CA 1 ATOM 4266 C C . GLY A 1 534 ? -8.043 12.780 -24.443 1.00 10.60 ? 534 GLY A C 1 ATOM 4267 O O . GLY A 1 534 ? -7.087 12.676 -25.223 1.00 12.90 ? 534 GLY A O 1 ATOM 4268 N N . VAL A 1 535 ? -8.074 12.199 -23.246 1.00 8.53 ? 535 VAL A N 1 ATOM 4269 C CA . VAL A 1 535 ? -6.962 11.406 -22.742 1.00 7.74 ? 535 VAL A CA 1 ATOM 4270 C C . VAL A 1 535 ? -6.612 10.232 -23.660 1.00 7.13 ? 535 VAL A C 1 ATOM 4271 O O . VAL A 1 535 ? -5.455 10.074 -24.052 1.00 6.66 ? 535 VAL A O 1 ATOM 4272 C CB . VAL A 1 535 ? -7.280 10.912 -21.326 1.00 8.76 ? 535 VAL A CB 1 ATOM 4273 C CG1 . VAL A 1 535 ? -6.247 9.904 -20.868 1.00 10.66 ? 535 VAL A CG1 1 ATOM 4274 C CG2 . VAL A 1 535 ? -7.289 12.095 -20.376 1.00 8.48 ? 535 VAL A CG2 1 ATOM 4275 N N . PHE A 1 536 ? -7.601 9.403 -23.979 1.00 6.21 ? 536 PHE A N 1 ATOM 4276 C CA . PHE A 1 536 ? -7.410 8.269 -24.891 1.00 6.60 ? 536 PHE A CA 1 ATOM 4277 C C . PHE A 1 536 ? -8.569 8.333 -25.870 1.00 7.54 ? 536 PHE A C 1 ATOM 4278 O O . PHE A 1 536 ? -9.623 8.874 -25.535 1.00 9.05 ? 536 PHE A O 1 ATOM 4279 C CB . PHE A 1 536 ? -7.457 6.921 -24.161 1.00 5.79 ? 536 PHE A CB 1 ATOM 4280 C CG . PHE A 1 536 ? -6.173 6.546 -23.474 1.00 4.74 ? 536 PHE A CG 1 ATOM 4281 C CD1 . PHE A 1 536 ? -6.037 6.678 -22.099 1.00 3.22 ? 536 PHE A CD1 1 ATOM 4282 C CD2 . PHE A 1 536 ? -5.094 6.073 -24.207 1.00 5.41 ? 536 PHE A CD2 1 ATOM 4283 C CE1 . PHE A 1 536 ? -4.846 6.347 -21.466 1.00 3.23 ? 536 PHE A CE1 1 ATOM 4284 C CE2 . PHE A 1 536 ? -3.896 5.741 -23.578 1.00 5.59 ? 536 PHE A CE2 1 ATOM 4285 C CZ . PHE A 1 536 ? -3.776 5.880 -22.206 1.00 3.40 ? 536 PHE A CZ 1 ATOM 4286 N N . THR A 1 537 ? -8.393 7.778 -27.066 1.00 6.65 ? 537 THR A N 1 ATOM 4287 C CA . THR A 1 537 ? -9.453 7.811 -28.076 1.00 6.35 ? 537 THR A CA 1 ATOM 4288 C C . THR A 1 537 ? -10.561 6.780 -27.834 1.00 8.99 ? 537 THR A C 1 ATOM 4289 O O . THR A 1 537 ? -10.389 5.847 -27.046 1.00 9.60 ? 537 THR A O 1 ATOM 4290 C CB . THR A 1 537 ? -8.898 7.542 -29.445 1.00 5.36 ? 537 THR A CB 1 ATOM 4291 O OG1 . THR A 1 537 ? -8.727 6.129 -29.599 1.00 7.70 ? 537 THR A OG1 1 ATOM 4292 C CG2 . THR A 1 537 ? -7.563 8.227 -29.609 1.00 4.55 ? 537 THR A CG2 1 ATOM 4293 N N . GLU A 1 538 ? -11.688 6.955 -28.531 1.00 10.48 ? 538 GLU A N 1 ATOM 4294 C CA . GLU A 1 538 ? -12.846 6.064 -28.410 1.00 11.34 ? 538 GLU A CA 1 ATOM 4295 C C . GLU A 1 538 ? -12.368 4.648 -28.647 1.00 11.21 ? 538 GLU A C 1 ATOM 4296 O O . GLU A 1 538 ? -12.678 3.732 -27.880 1.00 10.31 ? 538 GLU A O 1 ATOM 4297 C CB . GLU A 1 538 ? -13.931 6.411 -29.453 1.00 14.52 ? 538 GLU A CB 1 ATOM 4298 C CG . GLU A 1 538 ? -15.344 5.852 -29.137 1.00 19.36 ? 538 GLU A CG 1 ATOM 4299 C CD . GLU A 1 538 ? -15.993 5.070 -30.296 1.00 21.66 ? 538 GLU A CD 1 ATOM 4300 O OE1 . GLU A 1 538 ? -16.309 3.875 -30.095 1.00 22.75 ? 538 GLU A OE1 1 ATOM 4301 O OE2 . GLU A 1 538 ? -16.198 5.639 -31.395 1.00 22.38 ? 538 GLU A OE2 1 ATOM 4302 N N . LYS A 1 539 ? -11.608 4.468 -29.720 1.00 10.65 ? 539 LYS A N 1 ATOM 4303 C CA . LYS A 1 539 ? -11.096 3.146 -30.035 1.00 11.79 ? 539 LYS A CA 1 ATOM 4304 C C . LYS A 1 539 ? -10.064 2.715 -28.996 1.00 10.77 ? 539 LYS A C 1 ATOM 4305 O O . LYS A 1 539 ? -10.162 1.615 -28.445 1.00 10.93 ? 539 LYS A O 1 ATOM 4306 C CB . LYS A 1 539 ? -10.504 3.117 -31.455 1.00 13.45 ? 539 LYS A CB 1 ATOM 4307 C CG . LYS A 1 539 ? -11.513 2.693 -32.536 1.00 16.37 ? 539 LYS A CG 1 ATOM 4308 C CD . LYS A 1 539 ? -11.038 3.045 -33.944 1.00 19.35 ? 539 LYS A CD 1 ATOM 4309 C CE . LYS A 1 539 ? -9.644 2.483 -34.224 1.00 22.24 ? 539 LYS A CE 1 ATOM 4310 N NZ . LYS A 1 539 ? -9.124 2.768 -35.607 1.00 22.37 ? 539 LYS A NZ 1 ATOM 4311 N N . GLN A 1 540 ? -9.096 3.581 -28.706 1.00 8.16 ? 540 GLN A N 1 ATOM 4312 C CA . GLN A 1 540 ? -8.064 3.251 -27.728 1.00 7.27 ? 540 GLN A CA 1 ATOM 4313 C C . GLN A 1 540 ? -8.649 2.694 -26.438 1.00 8.12 ? 540 GLN A C 1 ATOM 4314 O O . GLN A 1 540 ? -8.128 1.730 -25.885 1.00 7.87 ? 540 GLN A O 1 ATOM 4315 C CB . GLN A 1 540 ? -7.213 4.477 -27.415 1.00 6.59 ? 540 GLN A CB 1 ATOM 4316 C CG . GLN A 1 540 ? -6.366 4.931 -28.581 1.00 6.64 ? 540 GLN A CG 1 ATOM 4317 C CD . GLN A 1 540 ? -5.444 6.063 -28.209 1.00 6.45 ? 540 GLN A CD 1 ATOM 4318 O OE1 . GLN A 1 540 ? -5.759 6.871 -27.335 1.00 7.17 ? 540 GLN A OE1 1 ATOM 4319 N NE2 . GLN A 1 540 ? -4.304 6.142 -28.884 1.00 5.63 ? 540 GLN A NE2 1 ATOM 4320 N N . ARG A 1 541 ? -9.727 3.307 -25.960 1.00 8.96 ? 541 ARG A N 1 ATOM 4321 C CA . ARG A 1 541 ? -10.392 2.862 -24.740 1.00 9.86 ? 541 ARG A CA 1 ATOM 4322 C C . ARG A 1 541 ? -10.937 1.440 -24.922 1.00 11.52 ? 541 ARG A C 1 ATOM 4323 O O . ARG A 1 541 ? -10.588 0.514 -24.180 1.00 9.16 ? 541 ARG A O 1 ATOM 4324 C CB . ARG A 1 541 ? -11.559 3.806 -24.389 1.00 11.59 ? 541 ARG A CB 1 ATOM 4325 C CG . ARG A 1 541 ? -11.173 5.256 -24.082 1.00 12.65 ? 541 ARG A CG 1 ATOM 4326 C CD . ARG A 1 541 ? -12.313 6.013 -23.377 1.00 13.64 ? 541 ARG A CD 1 ATOM 4327 N NE . ARG A 1 541 ? -13.385 6.454 -24.276 1.00 15.13 ? 541 ARG A NE 1 ATOM 4328 C CZ . ARG A 1 541 ? -13.295 7.489 -25.113 1.00 14.67 ? 541 ARG A CZ 1 ATOM 4329 N NH1 . ARG A 1 541 ? -12.177 8.202 -25.175 1.00 14.57 ? 541 ARG A NH1 1 ATOM 4330 N NH2 . ARG A 1 541 ? -14.327 7.818 -25.884 1.00 13.35 ? 541 ARG A NH2 1 ATOM 4331 N N . ASP A 1 542 ? -11.804 1.286 -25.919 1.00 12.83 ? 542 ASP A N 1 ATOM 4332 C CA . ASP A 1 542 ? -12.424 0.002 -26.223 1.00 13.90 ? 542 ASP A CA 1 ATOM 4333 C C . ASP A 1 542 ? -11.463 -1.176 -26.151 1.00 13.82 ? 542 ASP A C 1 ATOM 4334 O O . ASP A 1 542 ? -11.881 -2.314 -25.945 1.00 14.63 ? 542 ASP A O 1 ATOM 4335 C CB . ASP A 1 542 ? -13.066 0.056 -27.609 1.00 15.97 ? 542 ASP A CB 1 ATOM 4336 C CG . ASP A 1 542 ? -14.557 0.266 -27.541 1.00 18.35 ? 542 ASP A CG 1 ATOM 4337 O OD1 . ASP A 1 542 ? -15.261 -0.667 -27.083 1.00 18.72 ? 542 ASP A OD1 1 ATOM 4338 O OD2 . ASP A 1 542 ? -15.019 1.362 -27.934 1.00 18.77 ? 542 ASP A OD2 1 ATOM 4339 N N . SER A 1 543 ? -10.177 -0.889 -26.321 1.00 12.50 ? 543 SER A N 1 ATOM 4340 C CA . SER A 1 543 ? -9.137 -1.903 -26.294 1.00 10.55 ? 543 SER A CA 1 ATOM 4341 C C . SER A 1 543 ? -8.501 -2.024 -24.912 1.00 8.85 ? 543 SER A C 1 ATOM 4342 O O . SER A 1 543 ? -7.893 -3.046 -24.590 1.00 8.03 ? 543 SER A O 1 ATOM 4343 C CB . SER A 1 543 ? -8.071 -1.560 -27.340 1.00 11.68 ? 543 SER A CB 1 ATOM 4344 O OG . SER A 1 543 ? -6.918 -2.369 -27.182 1.00 15.71 ? 543 SER A OG 1 ATOM 4345 N N . LEU A 1 544 ? -8.634 -0.975 -24.104 1.00 8.00 ? 544 LEU A N 1 ATOM 4346 C CA . LEU A 1 544 ? -8.082 -0.968 -22.750 1.00 7.53 ? 544 LEU A CA 1 ATOM 4347 C C . LEU A 1 544 ? -9.076 -1.622 -21.809 1.00 9.60 ? 544 LEU A C 1 ATOM 4348 O O . LEU A 1 544 ? -8.716 -2.072 -20.719 1.00 9.55 ? 544 LEU A O 1 ATOM 4349 C CB . LEU A 1 544 ? -7.788 0.461 -22.284 1.00 4.50 ? 544 LEU A CB 1 ATOM 4350 C CG . LEU A 1 544 ? -6.392 0.971 -22.642 1.00 4.18 ? 544 LEU A CG 1 ATOM 4351 C CD1 . LEU A 1 544 ? -6.363 2.496 -22.718 1.00 3.46 ? 544 LEU A CD1 1 ATOM 4352 C CD2 . LEU A 1 544 ? -5.413 0.443 -21.613 1.00 2.90 ? 544 LEU A CD2 1 ATOM 4353 N N . GLN A 1 545 ? -10.331 -1.683 -22.244 1.00 10.22 ? 545 GLN A N 1 ATOM 4354 C CA . GLN A 1 545 ? -11.378 -2.299 -21.441 1.00 10.69 ? 545 GLN A CA 1 ATOM 4355 C C . GLN A 1 545 ? -11.132 -3.783 -21.239 1.00 9.68 ? 545 GLN A C 1 ATOM 4356 O O . GLN A 1 545 ? -11.909 -4.448 -20.560 1.00 9.02 ? 545 GLN A O 1 ATOM 4357 C CB . GLN A 1 545 ? -12.737 -2.116 -22.112 1.00 15.54 ? 545 GLN A CB 1 ATOM 4358 C CG . GLN A 1 545 ? -13.513 -0.914 -21.632 1.00 22.18 ? 545 GLN A CG 1 ATOM 4359 C CD . GLN A 1 545 ? -14.575 -0.485 -22.627 1.00 25.84 ? 545 GLN A CD 1 ATOM 4360 O OE1 . GLN A 1 545 ? -15.544 0.191 -22.268 1.00 27.84 ? 545 GLN A OE1 1 ATOM 4361 N NE2 . GLN A 1 545 ? -14.390 -0.863 -23.895 1.00 27.71 ? 545 GLN A NE2 1 ATOM 4362 N N . LYS A 1 546 ? -10.055 -4.306 -21.817 1.00 7.03 ? 546 LYS A N 1 ATOM 4363 C CA . LYS A 1 546 ? -9.783 -5.726 -21.696 1.00 4.67 ? 546 LYS A CA 1 ATOM 4364 C C . LYS A 1 546 ? -8.485 -6.104 -21.015 1.00 3.13 ? 546 LYS A C 1 ATOM 4365 O O . LYS A 1 546 ? -8.153 -7.281 -20.948 1.00 3.21 ? 546 LYS A O 1 ATOM 4366 C CB . LYS A 1 546 ? -9.837 -6.397 -23.066 1.00 6.63 ? 546 LYS A CB 1 ATOM 4367 C CG . LYS A 1 546 ? -11.169 -6.283 -23.804 1.00 7.80 ? 546 LYS A CG 1 ATOM 4368 C CD . LYS A 1 546 ? -11.047 -6.980 -25.162 1.00 8.65 ? 546 LYS A CD 1 ATOM 4369 C CE . LYS A 1 546 ? -12.023 -6.432 -26.187 1.00 8.59 ? 546 LYS A CE 1 ATOM 4370 N NZ . LYS A 1 546 ? -11.737 -6.976 -27.546 1.00 8.14 ? 546 LYS A NZ 1 ATOM 4371 N N . VAL A 1 547 ? -7.731 -5.130 -20.530 1.00 2.01 ? 547 VAL A N 1 ATOM 4372 C CA . VAL A 1 547 ? -6.508 -5.470 -19.812 1.00 3.35 ? 547 VAL A CA 1 ATOM 4373 C C . VAL A 1 547 ? -6.940 -6.340 -18.623 1.00 3.21 ? 547 VAL A C 1 ATOM 4374 O O . VAL A 1 547 ? -8.054 -6.172 -18.113 1.00 4.59 ? 547 VAL A O 1 ATOM 4375 C CB . VAL A 1 547 ? -5.828 -4.215 -19.250 1.00 2.07 ? 547 VAL A CB 1 ATOM 4376 C CG1 . VAL A 1 547 ? -5.178 -3.425 -20.365 1.00 2.01 ? 547 VAL A CG1 1 ATOM 4377 C CG2 . VAL A 1 547 ? -6.859 -3.360 -18.535 1.00 2.00 ? 547 VAL A CG2 1 ATOM 4378 N N . SER A 1 548 ? -6.088 -7.275 -18.198 1.00 3.11 ? 548 SER A N 1 ATOM 4379 C CA . SER A 1 548 ? -6.393 -8.133 -17.036 1.00 4.92 ? 548 SER A CA 1 ATOM 4380 C C . SER A 1 548 ? -5.088 -8.483 -16.338 1.00 3.29 ? 548 SER A C 1 ATOM 4381 O O . SER A 1 548 ? -4.038 -8.524 -16.984 1.00 4.73 ? 548 SER A O 1 ATOM 4382 C CB . SER A 1 548 ? -7.114 -9.425 -17.451 1.00 2.78 ? 548 SER A CB 1 ATOM 4383 O OG . SER A 1 548 ? -6.262 -10.282 -18.180 1.00 2.00 ? 548 SER A OG 1 ATOM 4384 N N . PHE A 1 549 ? -5.127 -8.731 -15.032 1.00 2.30 ? 549 PHE A N 1 ATOM 4385 C CA . PHE A 1 549 ? -3.875 -9.051 -14.375 1.00 3.34 ? 549 PHE A CA 1 ATOM 4386 C C . PHE A 1 549 ? -3.396 -10.435 -14.809 1.00 2.22 ? 549 PHE A C 1 ATOM 4387 O O . PHE A 1 549 ? -2.205 -10.744 -14.720 1.00 2.77 ? 549 PHE A O 1 ATOM 4388 C CB . PHE A 1 549 ? -3.979 -8.967 -12.848 1.00 2.00 ? 549 PHE A CB 1 ATOM 4389 C CG . PHE A 1 549 ? -2.651 -9.066 -12.172 1.00 2.00 ? 549 PHE A CG 1 ATOM 4390 C CD1 . PHE A 1 549 ? -1.724 -8.040 -12.284 1.00 2.00 ? 549 PHE A CD1 1 ATOM 4391 C CD2 . PHE A 1 549 ? -2.280 -10.225 -11.517 1.00 2.00 ? 549 PHE A CD2 1 ATOM 4392 C CE1 . PHE A 1 549 ? -0.442 -8.170 -11.758 1.00 2.00 ? 549 PHE A CE1 1 ATOM 4393 C CE2 . PHE A 1 549 ? -1.006 -10.365 -10.991 1.00 2.18 ? 549 PHE A CE2 1 ATOM 4394 C CZ . PHE A 1 549 ? -0.084 -9.330 -11.115 1.00 2.00 ? 549 PHE A CZ 1 ATOM 4395 N N . SER A 1 550 ? -4.319 -11.254 -15.309 1.00 2.00 ? 550 SER A N 1 ATOM 4396 C CA . SER A 1 550 ? -3.967 -12.591 -15.777 1.00 2.00 ? 550 SER A CA 1 ATOM 4397 C C . SER A 1 550 ? -3.123 -12.446 -17.039 1.00 2.00 ? 550 SER A C 1 ATOM 4398 O O . SER A 1 550 ? -2.123 -13.138 -17.210 1.00 2.72 ? 550 SER A O 1 ATOM 4399 C CB . SER A 1 550 ? -5.221 -13.406 -16.104 1.00 2.00 ? 550 SER A CB 1 ATOM 4400 O OG . SER A 1 550 ? -6.260 -13.142 -15.183 1.00 2.00 ? 550 SER A OG 1 ATOM 4401 N N . ARG A 1 551 ? -3.558 -11.541 -17.926 1.00 2.00 ? 551 ARG A N 1 ATOM 4402 C CA . ARG A 1 551 ? -2.756 -11.330 -19.161 1.00 2.41 ? 551 ARG A CA 1 ATOM 4403 C C . ARG A 1 551 ? -1.400 -10.805 -18.819 1.00 3.52 ? 551 ARG A C 1 ATOM 4404 O O . ARG A 1 551 ? -0.409 -11.253 -19.397 1.00 3.41 ? 551 ARG A O 1 ATOM 4405 C CB . ARG A 1 551 ? -3.388 -10.366 -20.165 1.00 3.44 ? 551 ARG A CB 1 ATOM 4406 C CG . ARG A 1 551 ? -2.577 -10.283 -21.445 1.00 5.71 ? 551 ARG A CG 1 ATOM 4407 C CD . ARG A 1 551 ? -2.971 -11.364 -22.471 1.00 6.05 ? 551 ARG A CD 1 ATOM 4408 N NE . ARG A 1 551 ? -1.893 -12.297 -22.815 1.00 7.85 ? 551 ARG A NE 1 ATOM 4409 C CZ . ARG A 1 551 ? -1.995 -13.389 -23.569 1.00 8.69 ? 551 ARG A CZ 1 ATOM 4410 N NH1 . ARG A 1 551 ? -3.167 -13.715 -24.105 1.00 9.19 ? 551 ARG A NH1 1 ATOM 4411 N NH2 . ARG A 1 551 ? -0.936 -14.161 -23.787 1.00 7.59 ? 551 ARG A NH2 1 ATOM 4412 N N . LEU A 1 552 ? -1.327 -9.862 -17.880 1.00 2.15 ? 552 LEU A N 1 ATOM 4413 C CA . LEU A 1 552 ? -0.038 -9.319 -17.476 1.00 2.00 ? 552 LEU A CA 1 ATOM 4414 C C . LEU A 1 552 ? 0.889 -10.499 -17.232 1.00 2.00 ? 552 LEU A C 1 ATOM 4415 O O . LEU A 1 552 ? 1.962 -10.596 -17.832 1.00 2.00 ? 552 LEU A O 1 ATOM 4416 C CB . LEU A 1 552 ? -0.158 -8.505 -16.187 1.00 2.00 ? 552 LEU A CB 1 ATOM 4417 C CG . LEU A 1 552 ? 1.179 -7.911 -15.722 1.00 2.00 ? 552 LEU A CG 1 ATOM 4418 C CD1 . LEU A 1 552 ? 1.670 -6.923 -16.768 1.00 2.00 ? 552 LEU A CD1 1 ATOM 4419 C CD2 . LEU A 1 552 ? 1.023 -7.222 -14.387 1.00 2.00 ? 552 LEU A CD2 1 ATOM 4420 N N . ILE A 1 553 ? 0.451 -11.395 -16.349 1.00 2.52 ? 553 ILE A N 1 ATOM 4421 C CA . ILE A 1 553 ? 1.206 -12.598 -16.000 1.00 2.00 ? 553 ILE A CA 1 ATOM 4422 C C . ILE A 1 553 ? 1.704 -13.308 -17.253 1.00 2.00 ? 553 ILE A C 1 ATOM 4423 O O . ILE A 1 553 ? 2.882 -13.647 -17.353 1.00 2.00 ? 553 ILE A O 1 ATOM 4424 C CB . ILE A 1 553 ? 0.343 -13.627 -15.233 1.00 2.00 ? 553 ILE A CB 1 ATOM 4425 C CG1 . ILE A 1 553 ? -0.177 -13.047 -13.912 1.00 2.00 ? 553 ILE A CG1 1 ATOM 4426 C CG2 . ILE A 1 553 ? 1.152 -14.884 -15.012 1.00 2.61 ? 553 ILE A CG2 1 ATOM 4427 C CD1 . ILE A 1 553 ? 0.889 -12.625 -12.962 1.00 2.00 ? 553 ILE A CD1 1 ATOM 4428 N N . CYS A 1 554 ? 0.794 -13.531 -18.198 1.00 2.00 ? 554 CYS A N 1 ATOM 4429 C CA . CYS A 1 554 ? 1.118 -14.220 -19.440 1.00 2.00 ? 554 CYS A CA 1 ATOM 4430 C C . CYS A 1 554 ? 2.205 -13.565 -20.302 1.00 2.63 ? 554 CYS A C 1 ATOM 4431 O O . CYS A 1 554 ? 3.298 -14.109 -20.440 1.00 3.05 ? 554 CYS A O 1 ATOM 4432 C CB . CYS A 1 554 ? -0.145 -14.400 -20.278 1.00 2.34 ? 554 CYS A CB 1 ATOM 4433 S SG . CYS A 1 554 ? -1.447 -15.428 -19.527 1.00 2.12 ? 554 CYS A SG 1 ATOM 4434 N N . ASP A 1 555 ? 1.915 -12.407 -20.887 1.00 2.55 ? 555 ASP A N 1 ATOM 4435 C CA . ASP A 1 555 ? 2.896 -11.737 -21.742 1.00 2.31 ? 555 ASP A CA 1 ATOM 4436 C C . ASP A 1 555 ? 4.284 -11.551 -21.094 1.00 3.72 ? 555 ASP A C 1 ATOM 4437 O O . ASP A 1 555 ? 5.276 -11.369 -21.805 1.00 5.21 ? 555 ASP A O 1 ATOM 4438 C CB . ASP A 1 555 ? 2.386 -10.349 -22.198 1.00 2.00 ? 555 ASP A CB 1 ATOM 4439 C CG . ASP A 1 555 ? 1.061 -10.405 -22.959 1.00 2.00 ? 555 ASP A CG 1 ATOM 4440 O OD1 . ASP A 1 555 ? 0.805 -11.397 -23.673 1.00 2.35 ? 555 ASP A OD1 1 ATOM 4441 O OD2 . ASP A 1 555 ? 0.277 -9.433 -22.859 1.00 2.00 ? 555 ASP A OD2 1 ATOM 4442 N N . ASN A 1 556 ? 4.406 -11.642 -19.765 1.00 2.85 ? 556 ASN A N 1 ATOM 4443 C CA . ASN A 1 556 ? 5.693 -11.341 -19.137 1.00 2.57 ? 556 ASN A CA 1 ATOM 4444 C C . ASN A 1 556 ? 6.320 -12.431 -18.234 1.00 2.86 ? 556 ASN A C 1 ATOM 4445 O O . ASN A 1 556 ? 7.072 -12.128 -17.307 1.00 2.00 ? 556 ASN A O 1 ATOM 4446 C CB . ASN A 1 556 ? 5.578 -10.080 -18.304 1.00 3.15 ? 556 ASN A CB 1 ATOM 4447 C CG . ASN A 1 556 ? 5.630 -8.861 -19.182 1.00 3.22 ? 556 ASN A CG 1 ATOM 4448 O OD1 . ASN A 1 556 ? 6.607 -8.645 -19.900 1.00 5.55 ? 556 ASN A OD1 1 ATOM 4449 N ND2 . ASN A 1 556 ? 4.579 -8.057 -19.143 1.00 2.85 ? 556 ASN A ND2 1 ATOM 4450 N N . THR A 1 557 ? 6.016 -13.692 -18.525 1.00 4.12 ? 557 THR A N 1 ATOM 4451 C CA . THR A 1 557 ? 6.542 -14.847 -17.745 1.00 6.39 ? 557 THR A CA 1 ATOM 4452 C C . THR A 1 557 ? 6.384 -16.104 -18.558 1.00 5.83 ? 557 THR A C 1 ATOM 4453 O O . THR A 1 557 ? 5.826 -16.091 -19.654 1.00 6.70 ? 557 THR A O 1 ATOM 4454 C CB . THR A 1 557 ? 5.768 -15.005 -16.426 1.00 6.71 ? 557 THR A CB 1 ATOM 4455 O OG1 . THR A 1 557 ? 4.467 -15.528 -16.705 1.00 6.85 ? 557 THR A OG1 1 ATOM 4456 C CG2 . THR A 1 557 ? 5.645 -13.649 -15.727 1.00 7.35 ? 557 THR A CG2 1 ATOM 4457 N N . HIS A 1 558 ? 6.822 -17.203 -18.018 1.00 5.69 ? 558 HIS A N 1 ATOM 4458 C CA . HIS A 1 558 ? 6.741 -18.439 -18.757 1.00 5.46 ? 558 HIS A CA 1 ATOM 4459 C C . HIS A 1 558 ? 5.670 -19.373 -18.217 1.00 4.48 ? 558 HIS A C 1 ATOM 4460 O O . HIS A 1 558 ? 5.777 -20.605 -18.264 1.00 2.08 ? 558 HIS A O 1 ATOM 4461 C CB . HIS A 1 558 ? 8.102 -19.090 -18.741 1.00 6.24 ? 558 HIS A CB 1 ATOM 4462 C CG . HIS A 1 558 ? 9.110 -18.326 -19.640 1.00 5.78 ? 558 HIS A CG 1 ATOM 4463 N ND1 . HIS A 1 558 ? 10.466 -18.574 -19.590 1.00 6.25 ? 558 HIS A ND1 1 ATOM 4464 C CD2 . HIS A 1 558 ? 8.914 -17.372 -20.581 1.00 5.37 ? 558 HIS A CD2 1 ATOM 4465 C CE1 . HIS A 1 558 ? 11.062 -17.804 -20.484 1.00 6.60 ? 558 HIS A CE1 1 ATOM 4466 N NE2 . HIS A 1 558 ? 10.143 -17.066 -21.080 1.00 5.89 ? 558 HIS A NE2 1 ATOM 4467 N N . ILE A 1 559 ? 4.623 -18.737 -17.687 1.00 3.41 ? 559 ILE A N 1 ATOM 4468 C CA . ILE A 1 559 ? 3.465 -19.412 -17.118 1.00 2.25 ? 559 ILE A CA 1 ATOM 4469 C C . ILE A 1 559 ? 2.406 -19.455 -18.208 1.00 2.00 ? 559 ILE A C 1 ATOM 4470 O O . ILE A 1 559 ? 2.132 -18.444 -18.859 1.00 2.00 ? 559 ILE A O 1 ATOM 4471 C CB . ILE A 1 559 ? 2.928 -18.649 -15.890 1.00 2.00 ? 559 ILE A CB 1 ATOM 4472 C CG1 . ILE A 1 559 ? 4.095 -18.294 -14.957 1.00 2.09 ? 559 ILE A CG1 1 ATOM 4473 C CG2 . ILE A 1 559 ? 1.919 -19.513 -15.153 1.00 2.00 ? 559 ILE A CG2 1 ATOM 4474 C CD1 . ILE A 1 559 ? 3.721 -17.531 -13.710 1.00 2.00 ? 559 ILE A CD1 1 ATOM 4475 N N . THR A 1 560 ? 1.828 -20.632 -18.418 1.00 2.00 ? 560 THR A N 1 ATOM 4476 C CA . THR A 1 560 ? 0.829 -20.808 -19.462 1.00 2.80 ? 560 THR A CA 1 ATOM 4477 C C . THR A 1 560 ? -0.573 -21.105 -18.958 1.00 3.09 ? 560 THR A C 1 ATOM 4478 O O . THR A 1 560 ? -1.521 -21.138 -19.738 1.00 2.55 ? 560 THR A O 1 ATOM 4479 C CB . THR A 1 560 ? 1.218 -21.944 -20.399 1.00 2.34 ? 560 THR A CB 1 ATOM 4480 O OG1 . THR A 1 560 ? 1.126 -23.187 -19.693 1.00 4.80 ? 560 THR A OG1 1 ATOM 4481 C CG2 . THR A 1 560 ? 2.634 -21.756 -20.888 1.00 3.38 ? 560 THR A CG2 1 ATOM 4482 N N . LYS A 1 561 ? -0.711 -21.349 -17.665 1.00 3.79 ? 561 LYS A N 1 ATOM 4483 C CA . LYS A 1 561 ? -2.027 -21.627 -17.118 1.00 4.67 ? 561 LYS A CA 1 ATOM 4484 C C . LYS A 1 561 ? -2.304 -20.572 -16.043 1.00 4.35 ? 561 LYS A C 1 ATOM 4485 O O . LYS A 1 561 ? -1.590 -20.481 -15.035 1.00 2.38 ? 561 LYS A O 1 ATOM 4486 C CB . LYS A 1 561 ? -2.070 -23.040 -16.523 1.00 7.38 ? 561 LYS A CB 1 ATOM 4487 C CG . LYS A 1 561 ? -1.524 -24.147 -17.437 1.00 10.77 ? 561 LYS A CG 1 ATOM 4488 C CD . LYS A 1 561 ? -2.557 -24.673 -18.429 1.00 13.99 ? 561 LYS A CD 1 ATOM 4489 C CE . LYS A 1 561 ? -1.965 -25.788 -19.300 1.00 15.48 ? 561 LYS A CE 1 ATOM 4490 N NZ . LYS A 1 561 ? -2.945 -26.887 -19.588 1.00 17.67 ? 561 LYS A NZ 1 ATOM 4491 N N . VAL A 1 562 ? -3.331 -19.760 -16.291 1.00 3.66 ? 562 VAL A N 1 ATOM 4492 C CA . VAL A 1 562 ? -3.746 -18.690 -15.386 1.00 4.17 ? 562 VAL A CA 1 ATOM 4493 C C . VAL A 1 562 ? -5.276 -18.568 -15.388 1.00 4.77 ? 562 VAL A C 1 ATOM 4494 O O . VAL A 1 562 ? -5.923 -18.766 -16.420 1.00 4.19 ? 562 VAL A O 1 ATOM 4495 C CB . VAL A 1 562 ? -3.144 -17.337 -15.812 1.00 4.09 ? 562 VAL A CB 1 ATOM 4496 C CG1 . VAL A 1 562 ? -1.625 -17.404 -15.765 1.00 2.00 ? 562 VAL A CG1 1 ATOM 4497 C CG2 . VAL A 1 562 ? -3.632 -16.971 -17.215 1.00 4.62 ? 562 VAL A CG2 1 ATOM 4498 N N . PRO A 1 563 ? -5.865 -18.210 -14.238 1.00 2.47 ? 563 PRO A N 1 ATOM 4499 C CA . PRO A 1 563 ? -7.309 -18.054 -14.045 1.00 3.64 ? 563 PRO A CA 1 ATOM 4500 C C . PRO A 1 563 ? -7.848 -16.765 -14.633 1.00 5.17 ? 563 PRO A C 1 ATOM 4501 O O . PRO A 1 563 ? -7.103 -15.798 -14.796 1.00 7.08 ? 563 PRO A O 1 ATOM 4502 C CB . PRO A 1 563 ? -7.466 -18.073 -12.521 1.00 5.02 ? 563 PRO A CB 1 ATOM 4503 C CG . PRO A 1 563 ? -6.065 -18.443 -11.983 1.00 5.39 ? 563 PRO A CG 1 ATOM 4504 C CD . PRO A 1 563 ? -5.156 -17.853 -13.005 1.00 4.07 ? 563 PRO A CD 1 ATOM 4505 N N . LEU A 1 564 ? -9.146 -16.749 -14.932 1.00 3.25 ? 564 LEU A N 1 ATOM 4506 C CA . LEU A 1 564 ? -9.779 -15.566 -15.493 1.00 2.21 ? 564 LEU A CA 1 ATOM 4507 C C . LEU A 1 564 ? -9.862 -14.512 -14.410 1.00 2.00 ? 564 LEU A C 1 ATOM 4508 O O . LEU A 1 564 ? -9.617 -13.337 -14.647 1.00 3.14 ? 564 LEU A O 1 ATOM 4509 C CB . LEU A 1 564 ? -11.206 -15.861 -15.984 1.00 2.00 ? 564 LEU A CB 1 ATOM 4510 C CG . LEU A 1 564 ? -11.626 -16.984 -16.954 1.00 2.20 ? 564 LEU A CG 1 ATOM 4511 C CD1 . LEU A 1 564 ? -10.530 -17.248 -17.973 1.00 2.00 ? 564 LEU A CD1 1 ATOM 4512 C CD2 . LEU A 1 564 ? -11.952 -18.254 -16.171 1.00 2.00 ? 564 LEU A CD2 1 ATOM 4513 N N . HIS A 1 565 ? -10.188 -14.940 -13.204 1.00 2.00 ? 565 HIS A N 1 ATOM 4514 C CA . HIS A 1 565 ? -10.341 -13.995 -12.109 1.00 3.26 ? 565 HIS A CA 1 ATOM 4515 C C . HIS A 1 565 ? -9.246 -14.094 -11.041 1.00 3.73 ? 565 HIS A C 1 ATOM 4516 O O . HIS A 1 565 ? -9.465 -14.595 -9.930 1.00 3.45 ? 565 HIS A O 1 ATOM 4517 C CB . HIS A 1 565 ? -11.738 -14.196 -11.533 1.00 3.98 ? 565 HIS A CB 1 ATOM 4518 C CG . HIS A 1 565 ? -12.797 -14.262 -12.589 1.00 3.18 ? 565 HIS A CG 1 ATOM 4519 N ND1 . HIS A 1 565 ? -13.475 -13.148 -13.035 1.00 2.68 ? 565 HIS A ND1 1 ATOM 4520 C CD2 . HIS A 1 565 ? -13.230 -15.294 -13.352 1.00 2.98 ? 565 HIS A CD2 1 ATOM 4521 C CE1 . HIS A 1 565 ? -14.279 -13.491 -14.027 1.00 3.14 ? 565 HIS A CE1 1 ATOM 4522 N NE2 . HIS A 1 565 ? -14.149 -14.788 -14.240 1.00 3.11 ? 565 HIS A NE2 1 ATOM 4523 N N . ALA A 1 566 ? -8.072 -13.576 -11.406 1.00 3.33 ? 566 ALA A N 1 ATOM 4524 C CA . ALA A 1 566 ? -6.876 -13.580 -10.570 1.00 2.00 ? 566 ALA A CA 1 ATOM 4525 C C . ALA A 1 566 ? -7.027 -13.014 -9.175 1.00 2.26 ? 566 ALA A C 1 ATOM 4526 O O . ALA A 1 566 ? -6.088 -13.067 -8.389 1.00 2.38 ? 566 ALA A O 1 ATOM 4527 C CB . ALA A 1 566 ? -5.757 -12.850 -11.279 1.00 2.00 ? 566 ALA A CB 1 ATOM 4528 N N . PHE A 1 567 ? -8.184 -12.473 -8.836 1.00 3.05 ? 567 PHE A N 1 ATOM 4529 C CA . PHE A 1 567 ? -8.287 -11.925 -7.499 1.00 5.42 ? 567 PHE A CA 1 ATOM 4530 C C . PHE A 1 567 ? -8.953 -12.800 -6.447 1.00 5.90 ? 567 PHE A C 1 ATOM 4531 O O . PHE A 1 567 ? -8.648 -12.683 -5.264 1.00 5.73 ? 567 PHE A O 1 ATOM 4532 C CB . PHE A 1 567 ? -8.935 -10.538 -7.542 1.00 4.14 ? 567 PHE A CB 1 ATOM 4533 C CG . PHE A 1 567 ? -7.968 -9.435 -7.900 1.00 3.86 ? 567 PHE A CG 1 ATOM 4534 C CD1 . PHE A 1 567 ? -6.776 -9.288 -7.205 1.00 4.11 ? 567 PHE A CD1 1 ATOM 4535 C CD2 . PHE A 1 567 ? -8.255 -8.534 -8.914 1.00 4.60 ? 567 PHE A CD2 1 ATOM 4536 C CE1 . PHE A 1 567 ? -5.885 -8.257 -7.512 1.00 5.02 ? 567 PHE A CE1 1 ATOM 4537 C CE2 . PHE A 1 567 ? -7.366 -7.498 -9.226 1.00 4.87 ? 567 PHE A CE2 1 ATOM 4538 C CZ . PHE A 1 567 ? -6.182 -7.362 -8.523 1.00 3.96 ? 567 PHE A CZ 1 ATOM 4539 N N . GLN A 1 568 ? -9.838 -13.696 -6.855 1.00 7.46 ? 568 GLN A N 1 ATOM 4540 C CA . GLN A 1 568 ? -10.505 -14.543 -5.873 1.00 9.18 ? 568 GLN A CA 1 ATOM 4541 C C . GLN A 1 568 ? -9.772 -15.855 -5.646 1.00 9.37 ? 568 GLN A C 1 ATOM 4542 O O . GLN A 1 568 ? -8.603 -15.980 -5.995 1.00 10.19 ? 568 GLN A O 1 ATOM 4543 C CB . GLN A 1 568 ? -11.922 -14.815 -6.333 1.00 10.09 ? 568 GLN A CB 1 ATOM 4544 C CG . GLN A 1 568 ? -11.986 -15.173 -7.781 1.00 13.51 ? 568 GLN A CG 1 ATOM 4545 C CD . GLN A 1 568 ? -13.395 -15.176 -8.268 1.00 15.68 ? 568 GLN A CD 1 ATOM 4546 O OE1 . GLN A 1 568 ? -14.160 -14.260 -7.962 1.00 16.45 ? 568 GLN A OE1 1 ATOM 4547 N NE2 . GLN A 1 568 ? -13.760 -16.199 -9.036 1.00 17.11 ? 568 GLN A NE2 1 ATOM 4548 N N . ALA A 1 569 ? -10.447 -16.825 -5.039 1.00 10.51 ? 569 ALA A N 1 ATOM 4549 C CA . ALA A 1 569 ? -9.833 -18.128 -4.811 1.00 11.48 ? 569 ALA A CA 1 ATOM 4550 C C . ALA A 1 569 ? -9.829 -18.871 -6.152 1.00 13.37 ? 569 ALA A C 1 ATOM 4551 O O . ALA A 1 569 ? -10.745 -18.714 -6.966 1.00 14.77 ? 569 ALA A O 1 ATOM 4552 C CB . ALA A 1 569 ? -10.623 -18.916 -3.772 1.00 11.50 ? 569 ALA A CB 1 ATOM 4553 N N . ASN A 1 570 ? -8.799 -19.675 -6.383 1.00 12.19 ? 570 ASN A N 1 ATOM 4554 C CA . ASN A 1 570 ? -8.680 -20.417 -7.630 1.00 10.31 ? 570 ASN A CA 1 ATOM 4555 C C . ASN A 1 570 ? -7.855 -21.665 -7.385 1.00 12.21 ? 570 ASN A C 1 ATOM 4556 O O . ASN A 1 570 ? -6.648 -21.575 -7.146 1.00 12.05 ? 570 ASN A O 1 ATOM 4557 C CB . ASN A 1 570 ? -7.972 -19.568 -8.685 1.00 10.79 ? 570 ASN A CB 1 ATOM 4558 C CG . ASN A 1 570 ? -8.807 -18.407 -9.163 1.00 10.48 ? 570 ASN A CG 1 ATOM 4559 O OD1 . ASN A 1 570 ? -8.343 -17.263 -9.186 1.00 9.83 ? 570 ASN A OD1 1 ATOM 4560 N ND2 . ASN A 1 570 ? -10.042 -18.692 -9.567 1.00 10.28 ? 570 ASN A ND2 1 ATOM 4561 N N . ASN A 1 571 ? -8.496 -22.826 -7.446 1.00 13.58 ? 571 ASN A N 1 ATOM 4562 C CA . ASN A 1 571 ? -7.792 -24.081 -7.228 1.00 14.83 ? 571 ASN A CA 1 ATOM 4563 C C . ASN A 1 571 ? -7.243 -24.642 -8.520 1.00 15.33 ? 571 ASN A C 1 ATOM 4564 O O . ASN A 1 571 ? -7.897 -24.579 -9.560 1.00 16.61 ? 571 ASN A O 1 ATOM 4565 C CB . ASN A 1 571 ? -8.717 -25.103 -6.583 1.00 17.30 ? 571 ASN A CB 1 ATOM 4566 C CG . ASN A 1 571 ? -9.080 -24.728 -5.169 1.00 20.36 ? 571 ASN A CG 1 ATOM 4567 O OD1 . ASN A 1 571 ? -8.212 -24.647 -4.293 1.00 21.85 ? 571 ASN A OD1 1 ATOM 4568 N ND2 . ASN A 1 571 ? -10.365 -24.481 -4.933 1.00 21.13 ? 571 ASN A ND2 1 ATOM 4569 N N . TYR A 1 572 ? -6.029 -25.173 -8.455 1.00 14.38 ? 572 TYR A N 1 ATOM 4570 C CA . TYR A 1 572 ? -5.409 -25.761 -9.627 1.00 13.11 ? 572 TYR A CA 1 ATOM 4571 C C . TYR A 1 572 ? -5.905 -27.203 -9.693 1.00 12.72 ? 572 TYR A C 1 ATOM 4572 O O . TYR A 1 572 ? -5.979 -27.883 -8.673 1.00 14.06 ? 572 TYR A O 1 ATOM 4573 C CB . TYR A 1 572 ? -3.891 -25.737 -9.495 1.00 12.41 ? 572 TYR A CB 1 ATOM 4574 C CG . TYR A 1 572 ? -3.175 -26.245 -10.721 1.00 12.06 ? 572 TYR A CG 1 ATOM 4575 C CD1 . TYR A 1 572 ? -2.951 -25.414 -11.823 1.00 11.94 ? 572 TYR A CD1 1 ATOM 4576 C CD2 . TYR A 1 572 ? -2.747 -27.567 -10.794 1.00 11.98 ? 572 TYR A CD2 1 ATOM 4577 C CE1 . TYR A 1 572 ? -2.315 -25.892 -12.969 1.00 12.43 ? 572 TYR A CE1 1 ATOM 4578 C CE2 . TYR A 1 572 ? -2.113 -28.056 -11.931 1.00 13.39 ? 572 TYR A CE2 1 ATOM 4579 C CZ . TYR A 1 572 ? -1.899 -27.217 -13.018 1.00 13.18 ? 572 TYR A CZ 1 ATOM 4580 O OH . TYR A 1 572 ? -1.270 -27.707 -14.145 1.00 12.83 ? 572 TYR A OH 1 ATOM 4581 N N . PRO A 1 573 ? -6.223 -27.698 -10.898 1.00 11.82 ? 573 PRO A N 1 ATOM 4582 C CA . PRO A 1 573 ? -6.135 -26.981 -12.169 1.00 11.35 ? 573 PRO A CA 1 ATOM 4583 C C . PRO A 1 573 ? -7.478 -26.568 -12.759 1.00 11.76 ? 573 PRO A C 1 ATOM 4584 O O . PRO A 1 573 ? -7.513 -25.991 -13.842 1.00 10.84 ? 573 PRO A O 1 ATOM 4585 C CB . PRO A 1 573 ? -5.450 -27.992 -13.052 1.00 11.34 ? 573 PRO A CB 1 ATOM 4586 C CG . PRO A 1 573 ? -6.215 -29.243 -12.666 1.00 12.42 ? 573 PRO A CG 1 ATOM 4587 C CD . PRO A 1 573 ? -6.376 -29.143 -11.143 1.00 11.85 ? 573 PRO A CD 1 ATOM 4588 N N . HIS A 1 574 ? -8.579 -26.863 -12.073 1.00 12.89 ? 574 HIS A N 1 ATOM 4589 C CA . HIS A 1 574 ? -9.887 -26.505 -12.615 1.00 12.34 ? 574 HIS A CA 1 ATOM 4590 C C . HIS A 1 574 ? -10.094 -25.032 -12.887 1.00 10.94 ? 574 HIS A C 1 ATOM 4591 O O . HIS A 1 574 ? -10.725 -24.678 -13.875 1.00 11.63 ? 574 HIS A O 1 ATOM 4592 C CB . HIS A 1 574 ? -11.037 -26.964 -11.719 1.00 18.88 ? 574 HIS A CB 1 ATOM 4593 C CG . HIS A 1 574 ? -12.350 -26.326 -12.072 1.00 25.04 ? 574 HIS A CG 1 ATOM 4594 N ND1 . HIS A 1 574 ? -12.918 -26.437 -13.326 1.00 27.94 ? 574 HIS A ND1 1 ATOM 4595 C CD2 . HIS A 1 574 ? -13.176 -25.524 -11.356 1.00 27.16 ? 574 HIS A CD2 1 ATOM 4596 C CE1 . HIS A 1 574 ? -14.034 -25.728 -13.367 1.00 29.15 ? 574 HIS A CE1 1 ATOM 4597 N NE2 . HIS A 1 574 ? -14.213 -25.164 -12.185 1.00 29.04 ? 574 HIS A NE2 1 ATOM 4598 N N . ASP A 1 575 ? -9.594 -24.158 -12.029 1.00 7.77 ? 575 ASP A N 1 ATOM 4599 C CA . ASP A 1 575 ? -9.824 -22.750 -12.284 1.00 6.40 ? 575 ASP A CA 1 ATOM 4600 C C . ASP A 1 575 ? -8.801 -22.115 -13.195 1.00 5.11 ? 575 ASP A C 1 ATOM 4601 O O . ASP A 1 575 ? -8.920 -20.941 -13.537 1.00 4.67 ? 575 ASP A O 1 ATOM 4602 C CB . ASP A 1 575 ? -9.899 -21.982 -10.976 1.00 8.06 ? 575 ASP A CB 1 ATOM 4603 C CG . ASP A 1 575 ? -10.841 -22.625 -9.996 1.00 9.56 ? 575 ASP A CG 1 ATOM 4604 O OD1 . ASP A 1 575 ? -11.935 -23.058 -10.419 1.00 10.54 ? 575 ASP A OD1 1 ATOM 4605 O OD2 . ASP A 1 575 ? -10.488 -22.697 -8.802 1.00 10.42 ? 575 ASP A OD2 1 ATOM 4606 N N . PHE A 1 576 ? -7.805 -22.893 -13.601 1.00 3.85 ? 576 PHE A N 1 ATOM 4607 C CA . PHE A 1 576 ? -6.766 -22.382 -14.481 1.00 2.70 ? 576 PHE A CA 1 ATOM 4608 C C . PHE A 1 576 ? -7.015 -22.797 -15.925 1.00 4.08 ? 576 PHE A C 1 ATOM 4609 O O . PHE A 1 576 ? -7.453 -23.916 -16.191 1.00 5.21 ? 576 PHE A O 1 ATOM 4610 C CB . PHE A 1 576 ? -5.397 -22.878 -14.009 1.00 2.91 ? 576 PHE A CB 1 ATOM 4611 C CG . PHE A 1 576 ? -4.957 -22.274 -12.700 1.00 4.62 ? 576 PHE A CG 1 ATOM 4612 C CD1 . PHE A 1 576 ? -5.823 -22.232 -11.608 1.00 2.28 ? 576 PHE A CD1 1 ATOM 4613 C CD2 . PHE A 1 576 ? -3.677 -21.739 -12.558 1.00 4.81 ? 576 PHE A CD2 1 ATOM 4614 C CE1 . PHE A 1 576 ? -5.424 -21.670 -10.408 1.00 2.00 ? 576 PHE A CE1 1 ATOM 4615 C CE2 . PHE A 1 576 ? -3.270 -21.172 -11.352 1.00 3.48 ? 576 PHE A CE2 1 ATOM 4616 C CZ . PHE A 1 576 ? -4.145 -21.138 -10.280 1.00 2.00 ? 576 PHE A CZ 1 ATOM 4617 N N . VAL A 1 577 ? -6.762 -21.874 -16.849 1.00 4.43 ? 577 VAL A N 1 ATOM 4618 C CA . VAL A 1 577 ? -6.931 -22.120 -18.277 1.00 2.41 ? 577 VAL A CA 1 ATOM 4619 C C . VAL A 1 577 ? -5.643 -21.685 -18.944 1.00 4.20 ? 577 VAL A C 1 ATOM 4620 O O . VAL A 1 577 ? -4.792 -21.070 -18.299 1.00 3.49 ? 577 VAL A O 1 ATOM 4621 C CB . VAL A 1 577 ? -8.081 -21.297 -18.878 1.00 3.38 ? 577 VAL A CB 1 ATOM 4622 C CG1 . VAL A 1 577 ? -9.394 -21.706 -18.245 1.00 4.96 ? 577 VAL A CG1 1 ATOM 4623 C CG2 . VAL A 1 577 ? -7.819 -19.817 -18.674 1.00 3.98 ? 577 VAL A CG2 1 ATOM 4624 N N . ASP A 1 578 ? -5.503 -21.994 -20.233 1.00 5.61 ? 578 ASP A N 1 ATOM 4625 C CA . ASP A 1 578 ? -4.296 -21.639 -20.977 1.00 3.96 ? 578 ASP A CA 1 ATOM 4626 C C . ASP A 1 578 ? -4.300 -20.170 -21.335 1.00 2.61 ? 578 ASP A C 1 ATOM 4627 O O . ASP A 1 578 ? -5.336 -19.624 -21.685 1.00 2.00 ? 578 ASP A O 1 ATOM 4628 C CB . ASP A 1 578 ? -4.183 -22.466 -22.256 1.00 5.76 ? 578 ASP A CB 1 ATOM 4629 C CG . ASP A 1 578 ? -2.754 -22.543 -22.769 1.00 9.33 ? 578 ASP A CG 1 ATOM 4630 O OD1 . ASP A 1 578 ? -1.898 -23.176 -22.084 1.00 8.77 ? 578 ASP A OD1 1 ATOM 4631 O OD2 . ASP A 1 578 ? -2.491 -21.960 -23.849 1.00 9.68 ? 578 ASP A OD2 1 ATOM 4632 N N . CYS A 1 579 ? -3.134 -19.537 -21.255 1.00 2.00 ? 579 CYS A N 1 ATOM 4633 C CA . CYS A 1 579 ? -3.028 -18.119 -21.557 1.00 2.30 ? 579 CYS A CA 1 ATOM 4634 C C . CYS A 1 579 ? -3.663 -17.772 -22.885 1.00 5.49 ? 579 CYS A C 1 ATOM 4635 O O . CYS A 1 579 ? -3.938 -16.595 -23.153 1.00 6.15 ? 579 CYS A O 1 ATOM 4636 C CB . CYS A 1 579 ? -1.576 -17.671 -21.568 1.00 3.02 ? 579 CYS A CB 1 ATOM 4637 S SG . CYS A 1 579 ? -0.867 -17.326 -19.928 1.00 5.30 ? 579 CYS A SG 1 ATOM 4638 N N . SER A 1 580 ? -3.893 -18.792 -23.714 1.00 4.29 ? 580 SER A N 1 ATOM 4639 C CA . SER A 1 580 ? -4.515 -18.611 -25.028 1.00 2.54 ? 580 SER A CA 1 ATOM 4640 C C . SER A 1 580 ? -6.032 -18.440 -24.891 1.00 2.01 ? 580 SER A C 1 ATOM 4641 O O . SER A 1 580 ? -6.726 -18.108 -25.850 1.00 2.00 ? 580 SER A O 1 ATOM 4642 C CB . SER A 1 580 ? -4.218 -19.821 -25.911 1.00 2.87 ? 580 SER A CB 1 ATOM 4643 O OG . SER A 1 580 ? -4.705 -21.008 -25.307 1.00 2.00 ? 580 SER A OG 1 ATOM 4644 N N . ALA A 1 581 ? -6.533 -18.671 -23.683 1.00 2.58 ? 581 ALA A N 1 ATOM 4645 C CA . ALA A 1 581 ? -7.954 -18.557 -23.399 1.00 4.35 ? 581 ALA A CA 1 ATOM 4646 C C . ALA A 1 581 ? -8.327 -17.151 -22.951 1.00 5.59 ? 581 ALA A C 1 ATOM 4647 O O . ALA A 1 581 ? -9.508 -16.818 -22.862 1.00 7.75 ? 581 ALA A O 1 ATOM 4648 C CB . ALA A 1 581 ? -8.348 -19.559 -22.321 1.00 2.64 ? 581 ALA A CB 1 ATOM 4649 N N . ILE A 1 582 ? -7.328 -16.324 -22.663 1.00 5.52 ? 582 ILE A N 1 ATOM 4650 C CA . ILE A 1 582 ? -7.603 -14.963 -22.224 1.00 5.72 ? 582 ILE A CA 1 ATOM 4651 C C . ILE A 1 582 ? -7.114 -13.907 -23.219 1.00 8.90 ? 582 ILE A C 1 ATOM 4652 O O . ILE A 1 582 ? -6.035 -14.035 -23.815 1.00 8.32 ? 582 ILE A O 1 ATOM 4653 C CB . ILE A 1 582 ? -6.999 -14.703 -20.833 1.00 4.00 ? 582 ILE A CB 1 ATOM 4654 C CG1 . ILE A 1 582 ? -5.947 -13.604 -20.902 1.00 4.53 ? 582 ILE A CG1 1 ATOM 4655 C CG2 . ILE A 1 582 ? -6.375 -15.960 -20.303 1.00 5.50 ? 582 ILE A CG2 1 ATOM 4656 C CD1 . ILE A 1 582 ? -5.357 -13.272 -19.564 1.00 5.53 ? 582 ILE A CD1 1 ATOM 4657 N N . ASP A 1 583 ? -7.931 -12.865 -23.371 1.00 8.45 ? 583 ASP A N 1 ATOM 4658 C CA . ASP A 1 583 ? -7.696 -11.750 -24.288 1.00 8.75 ? 583 ASP A CA 1 ATOM 4659 C C . ASP A 1 583 ? -6.297 -11.136 -24.300 1.00 9.87 ? 583 ASP A C 1 ATOM 4660 O O . ASP A 1 583 ? -5.501 -11.392 -23.401 1.00 7.56 ? 583 ASP A O 1 ATOM 4661 C CB . ASP A 1 583 ? -8.749 -10.693 -24.019 1.00 12.28 ? 583 ASP A CB 1 ATOM 4662 C CG . ASP A 1 583 ? -10.145 -11.281 -24.004 1.00 14.99 ? 583 ASP A CG 1 ATOM 4663 O OD1 . ASP A 1 583 ? -10.421 -12.107 -23.100 1.00 16.05 ? 583 ASP A OD1 1 ATOM 4664 O OD2 . ASP A 1 583 ? -10.951 -10.932 -24.900 1.00 14.17 ? 583 ASP A OD2 1 ATOM 4665 N N . LYS A 1 584 ? -6.019 -10.298 -25.305 1.00 10.73 ? 584 LYS A N 1 ATOM 4666 C CA . LYS A 1 584 ? -4.681 -9.712 -25.483 1.00 10.46 ? 584 LYS A CA 1 ATOM 4667 C C . LYS A 1 584 ? -4.380 -8.207 -25.538 1.00 8.41 ? 584 LYS A C 1 ATOM 4668 O O . LYS A 1 584 ? -3.206 -7.851 -25.636 1.00 10.23 ? 584 LYS A O 1 ATOM 4669 C CB . LYS A 1 584 ? -4.029 -10.332 -26.733 1.00 11.66 ? 584 LYS A CB 1 ATOM 4670 C CG . LYS A 1 584 ? -3.374 -11.692 -26.520 1.00 14.61 ? 584 LYS A CG 1 ATOM 4671 C CD . LYS A 1 584 ? -2.985 -12.371 -27.852 1.00 17.17 ? 584 LYS A CD 1 ATOM 4672 C CE . LYS A 1 584 ? -1.881 -11.634 -28.633 1.00 18.86 ? 584 LYS A CE 1 ATOM 4673 N NZ . LYS A 1 584 ? -0.530 -11.660 -27.983 1.00 20.30 ? 584 LYS A NZ 1 ATOM 4674 N N . LEU A 1 585 ? -5.363 -7.318 -25.484 1.00 4.72 ? 585 LEU A N 1 ATOM 4675 C CA . LEU A 1 585 ? -5.019 -5.888 -25.577 1.00 4.65 ? 585 LEU A CA 1 ATOM 4676 C C . LEU A 1 585 ? -4.407 -5.579 -26.944 1.00 2.81 ? 585 LEU A C 1 ATOM 4677 O O . LEU A 1 585 ? -3.186 -5.594 -27.106 1.00 3.02 ? 585 LEU A O 1 ATOM 4678 C CB . LEU A 1 585 ? -3.985 -5.468 -24.508 1.00 2.56 ? 585 LEU A CB 1 ATOM 4679 C CG . LEU A 1 585 ? -3.341 -4.085 -24.756 1.00 2.00 ? 585 LEU A CG 1 ATOM 4680 C CD1 . LEU A 1 585 ? -4.378 -3.008 -24.528 1.00 2.00 ? 585 LEU A CD1 1 ATOM 4681 C CD2 . LEU A 1 585 ? -2.155 -3.846 -23.856 1.00 2.00 ? 585 LEU A CD2 1 ATOM 4682 N N . ASP A 1 586 ? -5.244 -5.289 -27.924 1.00 2.00 ? 586 ASP A N 1 ATOM 4683 C CA . ASP A 1 586 ? -4.737 -4.978 -29.243 1.00 3.25 ? 586 ASP A CA 1 ATOM 4684 C C . ASP A 1 586 ? -4.231 -3.537 -29.291 1.00 2.00 ? 586 ASP A C 1 ATOM 4685 O O . ASP A 1 586 ? -4.968 -2.606 -29.005 1.00 2.00 ? 586 ASP A O 1 ATOM 4686 C CB . ASP A 1 586 ? -5.846 -5.224 -30.268 1.00 4.60 ? 586 ASP A CB 1 ATOM 4687 C CG . ASP A 1 586 ? -5.587 -4.545 -31.585 1.00 6.11 ? 586 ASP A CG 1 ATOM 4688 O OD1 . ASP A 1 586 ? -4.402 -4.376 -31.946 1.00 7.60 ? 586 ASP A OD1 1 ATOM 4689 O OD2 . ASP A 1 586 ? -6.577 -4.192 -32.263 1.00 7.04 ? 586 ASP A OD2 1 ATOM 4690 N N . LEU A 1 587 ? -2.961 -3.354 -29.632 1.00 2.00 ? 587 LEU A N 1 ATOM 4691 C CA . LEU A 1 587 ? -2.402 -2.009 -29.706 1.00 3.70 ? 587 LEU A CA 1 ATOM 4692 C C . LEU A 1 587 ? -2.517 -1.408 -31.112 1.00 4.15 ? 587 LEU A C 1 ATOM 4693 O O . LEU A 1 587 ? -1.974 -0.331 -31.386 1.00 4.42 ? 587 LEU A O 1 ATOM 4694 C CB . LEU A 1 587 ? -0.931 -2.010 -29.268 1.00 3.23 ? 587 LEU A CB 1 ATOM 4695 C CG . LEU A 1 587 ? -0.626 -2.364 -27.807 1.00 5.17 ? 587 LEU A CG 1 ATOM 4696 C CD1 . LEU A 1 587 ? 0.862 -2.230 -27.560 1.00 6.88 ? 587 LEU A CD1 1 ATOM 4697 C CD2 . LEU A 1 587 ? -1.382 -1.444 -26.860 1.00 6.02 ? 587 LEU A CD2 1 ATOM 4698 N N . SER A 1 588 ? -3.240 -2.089 -31.998 1.00 3.73 ? 588 SER A N 1 ATOM 4699 C CA . SER A 1 588 ? -3.401 -1.609 -33.370 1.00 3.80 ? 588 SER A CA 1 ATOM 4700 C C . SER A 1 588 ? -3.968 -0.192 -33.437 1.00 2.47 ? 588 SER A C 1 ATOM 4701 O O . SER A 1 588 ? -3.636 0.579 -34.335 1.00 2.45 ? 588 SER A O 1 ATOM 4702 C CB . SER A 1 588 ? -4.294 -2.561 -34.179 1.00 2.94 ? 588 SER A CB 1 ATOM 4703 O OG . SER A 1 588 ? -5.664 -2.398 -33.860 1.00 3.01 ? 588 SER A OG 1 ATOM 4704 N N . PRO A 1 589 ? -4.835 0.169 -32.487 1.00 3.07 ? 589 PRO A N 1 ATOM 4705 C CA . PRO A 1 589 ? -5.400 1.513 -32.513 1.00 4.51 ? 589 PRO A CA 1 ATOM 4706 C C . PRO A 1 589 ? -4.397 2.580 -32.090 1.00 6.30 ? 589 PRO A C 1 ATOM 4707 O O . PRO A 1 589 ? -4.702 3.767 -32.143 1.00 7.46 ? 589 PRO A O 1 ATOM 4708 C CB . PRO A 1 589 ? -6.577 1.404 -31.556 1.00 4.48 ? 589 PRO A CB 1 ATOM 4709 C CG . PRO A 1 589 ? -6.056 0.454 -30.534 1.00 4.72 ? 589 PRO A CG 1 ATOM 4710 C CD . PRO A 1 589 ? -5.422 -0.617 -31.391 1.00 3.62 ? 589 PRO A CD 1 ATOM 4711 N N . TRP A 1 590 ? -3.211 2.179 -31.643 1.00 7.18 ? 590 TRP A N 1 ATOM 4712 C CA . TRP A 1 590 ? -2.209 3.182 -31.277 1.00 9.79 ? 590 TRP A CA 1 ATOM 4713 C C . TRP A 1 590 ? -1.348 3.466 -32.517 1.00 13.15 ? 590 TRP A C 1 ATOM 4714 O O . TRP A 1 590 ? -0.415 4.273 -32.474 1.00 12.56 ? 590 TRP A O 1 ATOM 4715 C CB . TRP A 1 590 ? -1.327 2.701 -30.115 1.00 6.93 ? 590 TRP A CB 1 ATOM 4716 C CG . TRP A 1 590 ? -1.826 3.071 -28.728 1.00 4.65 ? 590 TRP A CG 1 ATOM 4717 C CD1 . TRP A 1 590 ? -1.378 4.096 -27.928 1.00 3.88 ? 590 TRP A CD1 1 ATOM 4718 C CD2 . TRP A 1 590 ? -2.836 2.391 -27.973 1.00 3.15 ? 590 TRP A CD2 1 ATOM 4719 N NE1 . TRP A 1 590 ? -2.049 4.085 -26.721 1.00 2.57 ? 590 TRP A NE1 1 ATOM 4720 C CE2 . TRP A 1 590 ? -2.948 3.050 -26.727 1.00 2.45 ? 590 TRP A CE2 1 ATOM 4721 C CE3 . TRP A 1 590 ? -3.658 1.286 -28.230 1.00 2.00 ? 590 TRP A CE3 1 ATOM 4722 C CZ2 . TRP A 1 590 ? -3.848 2.637 -25.746 1.00 2.46 ? 590 TRP A CZ2 1 ATOM 4723 C CZ3 . TRP A 1 590 ? -4.551 0.876 -27.253 1.00 2.00 ? 590 TRP A CZ3 1 ATOM 4724 C CH2 . TRP A 1 590 ? -4.639 1.549 -26.028 1.00 2.00 ? 590 TRP A CH2 1 ATOM 4725 N N . ALA A 1 591 ? -1.689 2.799 -33.620 1.00 16.68 ? 591 ALA A N 1 ATOM 4726 C CA . ALA A 1 591 ? -0.986 2.936 -34.894 1.00 20.64 ? 591 ALA A CA 1 ATOM 4727 C C . ALA A 1 591 ? -1.238 4.281 -35.565 1.00 25.11 ? 591 ALA A C 1 ATOM 4728 O O . ALA A 1 591 ? -2.338 4.543 -36.059 1.00 26.09 ? 591 ALA A O 1 ATOM 4729 C CB . ALA A 1 591 ? -1.404 1.819 -35.828 1.00 19.48 ? 591 ALA A CB 1 ATOM 4730 N N . SER A 1 592 ? -0.212 5.125 -35.589 1.00 30.18 ? 592 SER A N 1 ATOM 4731 C CA . SER A 1 592 ? -0.306 6.444 -36.206 1.00 34.71 ? 592 SER A CA 1 ATOM 4732 C C . SER A 1 592 ? 0.140 6.253 -37.650 1.00 38.86 ? 592 SER A C 1 ATOM 4733 O O . SER A 1 592 ? 1.026 5.437 -37.919 1.00 39.31 ? 592 SER A O 1 ATOM 4734 C CB . SER A 1 592 ? 0.624 7.430 -35.485 1.00 34.42 ? 592 SER A CB 1 ATOM 4735 O OG . SER A 1 592 ? 0.078 8.738 -35.435 1.00 33.31 ? 592 SER A OG 1 ATOM 4736 N N . ARG A 1 593 ? -0.477 6.993 -38.571 1.00 44.46 ? 593 ARG A N 1 ATOM 4737 C CA . ARG A 1 593 ? -0.152 6.892 -39.995 1.00 49.50 ? 593 ARG A CA 1 ATOM 4738 C C . ARG A 1 593 ? 0.008 8.247 -40.712 1.00 52.72 ? 593 ARG A C 1 ATOM 4739 O O . ARG A 1 593 ? -0.962 8.976 -40.953 1.00 52.33 ? 593 ARG A O 1 ATOM 4740 C CB . ARG A 1 593 ? -1.199 6.007 -40.690 1.00 50.16 ? 593 ARG A CB 1 ATOM 4741 C CG . ARG A 1 593 ? -0.992 4.518 -40.387 1.00 52.49 ? 593 ARG A CG 1 ATOM 4742 C CD . ARG A 1 593 ? -2.261 3.690 -40.530 1.00 54.20 ? 593 ARG A CD 1 ATOM 4743 N NE . ARG A 1 593 ? -2.778 3.689 -41.894 1.00 56.99 ? 593 ARG A NE 1 ATOM 4744 C CZ . ARG A 1 593 ? -3.925 3.120 -42.259 1.00 58.37 ? 593 ARG A CZ 1 ATOM 4745 N NH1 . ARG A 1 593 ? -4.681 2.499 -41.358 1.00 58.63 ? 593 ARG A NH1 1 ATOM 4746 N NH2 . ARG A 1 593 ? -4.321 3.177 -43.526 1.00 58.57 ? 593 ARG A NH2 1 ATOM 4747 N N . GLU A 1 594 ? 1.268 8.543 -41.037 1.00 56.49 ? 594 GLU A N 1 ATOM 4748 C CA . GLU A 1 594 ? 1.753 9.762 -41.707 1.00 59.50 ? 594 GLU A CA 1 ATOM 4749 C C . GLU A 1 594 ? 0.859 10.969 -42.033 1.00 60.97 ? 594 GLU A C 1 ATOM 4750 O O . GLU A 1 594 ? 0.685 11.870 -41.203 1.00 60.98 ? 594 GLU A O 1 ATOM 4751 C CB . GLU A 1 594 ? 2.518 9.375 -42.990 1.00 60.87 ? 594 GLU A CB 1 ATOM 4752 C CG . GLU A 1 594 ? 3.573 8.300 -42.777 1.00 62.45 ? 594 GLU A CG 1 ATOM 4753 C CD . GLU A 1 594 ? 4.129 8.315 -41.362 1.00 63.52 ? 594 GLU A CD 1 ATOM 4754 O OE1 . GLU A 1 594 ? 4.833 9.287 -41.002 1.00 63.87 ? 594 GLU A OE1 1 ATOM 4755 O OE2 . GLU A 1 594 ? 3.845 7.357 -40.608 1.00 63.16 ? 594 GLU A OE2 1 ATOM 4756 N N . ASN A 1 595 ? 0.324 10.985 -43.253 1.00 61.86 ? 595 ASN A N 1 ATOM 4757 C CA . ASN A 1 595 ? -0.488 12.088 -43.766 1.00 62.60 ? 595 ASN A CA 1 ATOM 4758 C C . ASN A 1 595 ? -1.958 12.161 -43.350 1.00 63.11 ? 595 ASN A C 1 ATOM 4759 O O . ASN A 1 595 ? -2.630 13.129 -43.782 1.00 63.13 ? 595 ASN A O 1 ATOM 4760 C CB . ASN A 1 595 ? -0.376 12.086 -45.291 1.00 62.82 ? 595 ASN A CB 1 ATOM 4761 C CG . ASN A 1 595 ? 1.070 12.138 -45.762 1.00 63.34 ? 595 ASN A CG 1 ATOM 4762 O OD1 . ASN A 1 595 ? 1.641 13.215 -45.937 1.00 63.54 ? 595 ASN A OD1 1 ATOM 4763 N ND2 . ASN A 1 595 ? 1.677 10.967 -45.945 1.00 62.79 ? 595 ASN A ND2 1 ATOM 4764 O OXT . ASN A 1 595 ? -2.420 11.269 -42.605 1.00 63.13 ? 595 ASN A OXT 1 ATOM 4765 N N . SER B 1 1 ? 12.305 59.387 28.808 1.00 78.30 ? 1 SER B N 1 ATOM 4766 C CA . SER B 1 1 ? 11.285 58.372 29.192 1.00 78.51 ? 1 SER B CA 1 ATOM 4767 C C . SER B 1 1 ? 11.924 57.078 29.711 1.00 78.35 ? 1 SER B C 1 ATOM 4768 O O . SER B 1 1 ? 13.155 56.917 29.681 1.00 78.25 ? 1 SER B O 1 ATOM 4769 C CB . SER B 1 1 ? 10.380 58.071 27.985 1.00 78.50 ? 1 SER B CB 1 ATOM 4770 O OG . SER B 1 1 ? 9.550 56.940 28.204 1.00 77.44 ? 1 SER B OG 1 ATOM 4771 N N . TRP B 1 2 ? 11.054 56.185 30.190 1.00 78.46 ? 2 TRP B N 1 ATOM 4772 C CA . TRP B 1 2 ? 11.389 54.865 30.743 1.00 79.03 ? 2 TRP B CA 1 ATOM 4773 C C . TRP B 1 2 ? 10.655 53.762 29.963 1.00 79.01 ? 2 TRP B C 1 ATOM 4774 O O . TRP B 1 2 ? 9.626 53.260 30.432 1.00 79.04 ? 2 TRP B O 1 ATOM 4775 C CB . TRP B 1 2 ? 10.935 54.757 32.205 1.00 77.64 ? 2 TRP B CB 1 ATOM 4776 C CG . TRP B 1 2 ? 11.976 54.995 33.244 1.00 76.86 ? 2 TRP B CG 1 ATOM 4777 C CD1 . TRP B 1 2 ? 12.719 54.056 33.907 1.00 76.35 ? 2 TRP B CD1 1 ATOM 4778 C CD2 . TRP B 1 2 ? 12.373 56.259 33.765 1.00 76.82 ? 2 TRP B CD2 1 ATOM 4779 N NE1 . TRP B 1 2 ? 13.553 54.661 34.814 1.00 76.17 ? 2 TRP B NE1 1 ATOM 4780 C CE2 . TRP B 1 2 ? 13.362 56.016 34.746 1.00 76.50 ? 2 TRP B CE2 1 ATOM 4781 C CE3 . TRP B 1 2 ? 11.989 57.582 33.498 1.00 76.32 ? 2 TRP B CE3 1 ATOM 4782 C CZ2 . TRP B 1 2 ? 13.972 57.049 35.462 1.00 76.17 ? 2 TRP B CZ2 1 ATOM 4783 C CZ3 . TRP B 1 2 ? 12.595 58.609 34.211 1.00 75.80 ? 2 TRP B CZ3 1 ATOM 4784 C CH2 . TRP B 1 2 ? 13.576 58.336 35.182 1.00 75.77 ? 2 TRP B CH2 1 ATOM 4785 N N . GLU B 1 3 ? 11.157 53.396 28.783 1.00 78.60 ? 3 GLU B N 1 ATOM 4786 C CA . GLU B 1 3 ? 10.552 52.315 28.000 1.00 78.04 ? 3 GLU B CA 1 ATOM 4787 C C . GLU B 1 3 ? 11.109 51.060 28.635 1.00 78.48 ? 3 GLU B C 1 ATOM 4788 O O . GLU B 1 3 ? 11.479 50.121 27.925 1.00 78.77 ? 3 GLU B O 1 ATOM 4789 C CB . GLU B 1 3 ? 11.019 52.332 26.545 1.00 78.09 ? 3 GLU B CB 1 ATOM 4790 C CG . GLU B 1 3 ? 10.104 51.568 25.592 1.00 77.61 ? 3 GLU B CG 1 ATOM 4791 C CD . GLU B 1 3 ? 10.845 50.633 24.636 1.00 77.50 ? 3 GLU B CD 1 ATOM 4792 O OE1 . GLU B 1 3 ? 11.065 49.458 25.000 1.00 77.45 ? 3 GLU B OE1 1 ATOM 4793 O OE2 . GLU B 1 3 ? 11.207 51.070 23.523 1.00 77.04 ? 3 GLU B OE2 1 ATOM 4794 N N . VAL B 1 4 ? 11.220 51.072 29.966 1.00 78.34 ? 4 VAL B N 1 ATOM 4795 C CA . VAL B 1 4 ? 11.750 49.938 30.709 1.00 77.36 ? 4 VAL B CA 1 ATOM 4796 C C . VAL B 1 4 ? 10.995 48.677 30.286 1.00 77.11 ? 4 VAL B C 1 ATOM 4797 O O . VAL B 1 4 ? 10.145 48.161 31.008 1.00 76.46 ? 4 VAL B O 1 ATOM 4798 C CB . VAL B 1 4 ? 11.612 50.168 32.225 1.00 77.18 ? 4 VAL B CB 1 ATOM 4799 C CG1 . VAL B 1 4 ? 12.396 51.385 32.609 1.00 77.00 ? 4 VAL B CG1 1 ATOM 4800 C CG2 . VAL B 1 4 ? 10.147 50.329 32.614 1.00 77.63 ? 4 VAL B CG2 1 ATOM 4801 N N . GLY B 1 5 ? 11.370 48.140 29.152 1.00 76.92 ? 5 GLY B N 1 ATOM 4802 C CA . GLY B 1 5 ? 10.812 46.970 28.589 1.00 75.97 ? 5 GLY B CA 1 ATOM 4803 C C . GLY B 1 5 ? 10.175 45.874 29.473 1.00 74.83 ? 5 GLY B C 1 ATOM 4804 O O . GLY B 1 5 ? 8.944 45.863 29.657 1.00 75.33 ? 5 GLY B O 1 ATOM 4805 N N . CYS B 1 6 ? 10.976 44.871 29.987 1.00 72.65 ? 6 CYS B N 1 ATOM 4806 C CA . CYS B 1 6 ? 10.451 43.683 30.745 1.00 70.63 ? 6 CYS B CA 1 ATOM 4807 C C . CYS B 1 6 ? 11.148 43.383 32.110 1.00 71.42 ? 6 CYS B C 1 ATOM 4808 O O . CYS B 1 6 ? 12.186 44.003 32.394 1.00 72.11 ? 6 CYS B O 1 ATOM 4809 C CB . CYS B 1 6 ? 10.474 42.434 29.844 1.00 66.25 ? 6 CYS B CB 1 ATOM 4810 S SG . CYS B 1 6 ? 12.144 41.844 29.416 1.00 60.04 ? 6 CYS B SG 1 ATOM 4811 N N . GLY B 1 7 ? 10.656 42.451 32.997 1.00 72.03 ? 7 GLY B N 1 ATOM 4812 C CA . GLY B 1 7 ? 11.157 42.428 34.402 1.00 72.28 ? 7 GLY B CA 1 ATOM 4813 C C . GLY B 1 7 ? 12.226 41.546 35.087 1.00 71.94 ? 7 GLY B C 1 ATOM 4814 O O . GLY B 1 7 ? 13.380 41.972 35.242 1.00 71.67 ? 7 GLY B O 1 ATOM 4815 N N . ALA B 1 8 ? 11.857 40.315 35.498 1.00 71.48 ? 8 ALA B N 1 ATOM 4816 C CA . ALA B 1 8 ? 12.767 39.522 36.337 1.00 70.17 ? 8 ALA B CA 1 ATOM 4817 C C . ALA B 1 8 ? 12.222 38.365 37.162 1.00 69.10 ? 8 ALA B C 1 ATOM 4818 O O . ALA B 1 8 ? 11.091 38.453 37.665 1.00 68.99 ? 8 ALA B O 1 ATOM 4819 C CB . ALA B 1 8 ? 13.532 40.442 37.369 1.00 69.52 ? 8 ALA B CB 1 ATOM 4820 N N . PRO B 1 9 ? 13.032 37.265 37.232 1.00 68.25 ? 9 PRO B N 1 ATOM 4821 C CA . PRO B 1 9 ? 12.499 36.203 38.075 1.00 67.25 ? 9 PRO B CA 1 ATOM 4822 C C . PRO B 1 9 ? 12.747 36.804 39.538 1.00 65.47 ? 9 PRO B C 1 ATOM 4823 O O . PRO B 1 9 ? 11.850 37.431 40.171 1.00 65.82 ? 9 PRO B O 1 ATOM 4824 C CB . PRO B 1 9 ? 13.411 35.001 37.829 1.00 67.63 ? 9 PRO B CB 1 ATOM 4825 C CG . PRO B 1 9 ? 14.833 35.622 37.466 1.00 68.10 ? 9 PRO B CG 1 ATOM 4826 C CD . PRO B 1 9 ? 14.488 37.141 37.039 1.00 68.16 ? 9 PRO B CD 1 ATOM 4827 N N . VAL B 1 10 ? 13.991 36.604 40.016 1.00 62.56 ? 10 VAL B N 1 ATOM 4828 C CA . VAL B 1 10 ? 14.613 37.110 41.258 1.00 58.30 ? 10 VAL B CA 1 ATOM 4829 C C . VAL B 1 10 ? 14.092 36.679 42.631 1.00 56.30 ? 10 VAL B C 1 ATOM 4830 O O . VAL B 1 10 ? 12.941 36.955 42.998 1.00 56.96 ? 10 VAL B O 1 ATOM 4831 C CB . VAL B 1 10 ? 14.604 38.654 41.291 1.00 57.78 ? 10 VAL B CB 1 ATOM 4832 C CG1 . VAL B 1 10 ? 14.728 39.194 39.871 1.00 56.40 ? 10 VAL B CG1 1 ATOM 4833 C CG2 . VAL B 1 10 ? 13.355 39.186 41.984 1.00 56.88 ? 10 VAL B CG2 1 ATOM 4834 N N . PRO B 1 11 ? 14.980 36.008 43.363 1.00 54.33 ? 11 PRO B N 1 ATOM 4835 C CA . PRO B 1 11 ? 14.662 35.784 44.790 1.00 52.19 ? 11 PRO B CA 1 ATOM 4836 C C . PRO B 1 11 ? 14.329 37.099 45.453 1.00 50.84 ? 11 PRO B C 1 ATOM 4837 O O . PRO B 1 11 ? 15.241 37.910 45.670 1.00 50.43 ? 11 PRO B O 1 ATOM 4838 C CB . PRO B 1 11 ? 15.872 35.058 45.305 1.00 51.73 ? 11 PRO B CB 1 ATOM 4839 C CG . PRO B 1 11 ? 16.139 34.157 44.121 1.00 52.65 ? 11 PRO B CG 1 ATOM 4840 C CD . PRO B 1 11 ? 15.565 34.756 42.875 1.00 53.90 ? 11 PRO B CD 1 ATOM 4841 N N . LEU B 1 12 ? 13.095 37.382 45.805 1.00 49.91 ? 12 LEU B N 1 ATOM 4842 C CA . LEU B 1 12 ? 12.755 38.636 46.457 1.00 49.46 ? 12 LEU B CA 1 ATOM 4843 C C . LEU B 1 12 ? 12.936 38.659 47.986 1.00 49.03 ? 12 LEU B C 1 ATOM 4844 O O . LEU B 1 12 ? 12.079 38.179 48.732 1.00 49.83 ? 12 LEU B O 1 ATOM 4845 C CB . LEU B 1 12 ? 11.312 38.998 46.076 1.00 49.00 ? 12 LEU B CB 1 ATOM 4846 C CG . LEU B 1 12 ? 10.616 40.215 46.681 1.00 48.89 ? 12 LEU B CG 1 ATOM 4847 C CD1 . LEU B 1 12 ? 9.906 40.982 45.575 1.00 48.49 ? 12 LEU B CD1 1 ATOM 4848 C CD2 . LEU B 1 12 ? 9.629 39.761 47.752 1.00 47.92 ? 12 LEU B CD2 1 ATOM 4849 N N . VAL B 1 13 ? 14.057 39.220 48.446 1.00 48.24 ? 13 VAL B N 1 ATOM 4850 C CA . VAL B 1 13 ? 14.336 39.340 49.883 1.00 48.38 ? 13 VAL B CA 1 ATOM 4851 C C . VAL B 1 13 ? 13.856 40.697 50.393 1.00 48.73 ? 13 VAL B C 1 ATOM 4852 O O . VAL B 1 13 ? 13.741 41.661 49.623 1.00 49.34 ? 13 VAL B O 1 ATOM 4853 C CB . VAL B 1 13 ? 15.845 39.230 50.216 1.00 48.01 ? 13 VAL B CB 1 ATOM 4854 C CG1 . VAL B 1 13 ? 16.203 37.799 50.577 1.00 48.52 ? 13 VAL B CG1 1 ATOM 4855 C CG2 . VAL B 1 13 ? 16.699 39.707 49.040 1.00 48.36 ? 13 VAL B CG2 1 ATOM 4856 N N . LYS B 1 14 ? 13.595 40.766 51.697 1.00 47.15 ? 14 LYS B N 1 ATOM 4857 C CA . LYS B 1 14 ? 13.106 41.986 52.328 1.00 44.57 ? 14 LYS B CA 1 ATOM 4858 C C . LYS B 1 14 ? 14.118 42.645 53.245 1.00 42.03 ? 14 LYS B C 1 ATOM 4859 O O . LYS B 1 14 ? 13.764 43.553 54.000 1.00 43.50 ? 14 LYS B O 1 ATOM 4860 C CB . LYS B 1 14 ? 11.824 41.658 53.119 1.00 46.03 ? 14 LYS B CB 1 ATOM 4861 C CG . LYS B 1 14 ? 12.042 40.615 54.208 1.00 46.69 ? 14 LYS B CG 1 ATOM 4862 C CD . LYS B 1 14 ? 11.052 40.812 55.352 1.00 48.04 ? 14 LYS B CD 1 ATOM 4863 C CE . LYS B 1 14 ? 10.654 39.475 55.969 1.00 48.39 ? 14 LYS B CE 1 ATOM 4864 N NZ . LYS B 1 14 ? 9.870 38.632 55.014 1.00 48.13 ? 14 LYS B NZ 1 ATOM 4865 N N . CYS B 1 15 ? 15.366 42.194 53.168 1.00 37.96 ? 15 CYS B N 1 ATOM 4866 C CA . CYS B 1 15 ? 16.422 42.708 54.032 1.00 35.08 ? 15 CYS B CA 1 ATOM 4867 C C . CYS B 1 15 ? 16.184 42.295 55.452 1.00 35.94 ? 15 CYS B C 1 ATOM 4868 O O . CYS B 1 15 ? 15.159 41.699 55.744 1.00 36.77 ? 15 CYS B O 1 ATOM 4869 C CB . CYS B 1 15 ? 16.512 44.222 53.870 1.00 29.72 ? 15 CYS B CB 1 ATOM 4870 S SG . CYS B 1 15 ? 16.917 44.776 52.184 1.00 19.82 ? 15 CYS B SG 1 ATOM 4871 N N . ASP B 1 16 ? 17.076 42.576 56.354 1.00 36.36 ? 16 ASP B N 1 ATOM 4872 C CA . ASP B 1 16 ? 16.734 42.408 57.737 1.00 36.76 ? 16 ASP B CA 1 ATOM 4873 C C . ASP B 1 16 ? 16.503 43.859 58.100 1.00 36.98 ? 16 ASP B C 1 ATOM 4874 O O . ASP B 1 16 ? 15.384 44.379 58.083 1.00 37.77 ? 16 ASP B O 1 ATOM 4875 C CB . ASP B 1 16 ? 17.806 41.836 58.671 1.00 37.54 ? 16 ASP B CB 1 ATOM 4876 C CG . ASP B 1 16 ? 17.732 42.397 60.093 1.00 37.47 ? 16 ASP B CG 1 ATOM 4877 O OD1 . ASP B 1 16 ? 16.628 42.739 60.540 1.00 37.17 ? 16 ASP B OD1 1 ATOM 4878 O OD2 . ASP B 1 16 ? 18.797 42.498 60.733 1.00 37.35 ? 16 ASP B OD2 1 ATOM 4879 N N . GLU B 1 17 ? 17.604 44.503 58.421 1.00 36.33 ? 17 GLU B N 1 ATOM 4880 C CA . GLU B 1 17 ? 17.627 45.897 58.710 1.00 36.36 ? 17 GLU B CA 1 ATOM 4881 C C . GLU B 1 17 ? 18.895 46.293 59.435 1.00 34.33 ? 17 GLU B C 1 ATOM 4882 O O . GLU B 1 17 ? 19.804 46.883 58.852 1.00 35.18 ? 17 GLU B O 1 ATOM 4883 C CB . GLU B 1 17 ? 16.418 46.313 59.547 1.00 38.31 ? 17 GLU B CB 1 ATOM 4884 C CG . GLU B 1 17 ? 16.203 47.811 59.547 1.00 43.44 ? 17 GLU B CG 1 ATOM 4885 C CD . GLU B 1 17 ? 16.753 48.474 58.282 1.00 45.73 ? 17 GLU B CD 1 ATOM 4886 O OE1 . GLU B 1 17 ? 17.984 48.710 58.223 1.00 46.80 ? 17 GLU B OE1 1 ATOM 4887 O OE2 . GLU B 1 17 ? 15.961 48.743 57.347 1.00 46.91 ? 17 GLU B OE2 1 ATOM 4888 N N . ASN B 1 18 ? 18.949 45.962 60.715 1.00 31.13 ? 18 ASN B N 1 ATOM 4889 C CA . ASN B 1 18 ? 20.107 46.286 61.528 1.00 28.95 ? 18 ASN B CA 1 ATOM 4890 C C . ASN B 1 18 ? 21.219 45.227 61.499 1.00 25.91 ? 18 ASN B C 1 ATOM 4891 O O . ASN B 1 18 ? 22.355 45.526 61.856 1.00 26.74 ? 18 ASN B O 1 ATOM 4892 C CB . ASN B 1 18 ? 19.658 46.515 62.977 1.00 31.35 ? 18 ASN B CB 1 ATOM 4893 C CG . ASN B 1 18 ? 19.602 47.987 63.349 1.00 32.58 ? 18 ASN B CG 1 ATOM 4894 O OD1 . ASN B 1 18 ? 18.805 48.393 64.199 1.00 32.25 ? 18 ASN B OD1 1 ATOM 4895 N ND2 . ASN B 1 18 ? 20.464 48.791 62.730 1.00 32.71 ? 18 ASN B ND2 1 ATOM 4896 N N . SER B 1 19 ? 20.908 44.007 61.064 1.00 21.35 ? 19 SER B N 1 ATOM 4897 C CA . SER B 1 19 ? 21.893 42.919 61.046 1.00 16.10 ? 19 SER B CA 1 ATOM 4898 C C . SER B 1 19 ? 23.324 43.250 60.647 1.00 11.80 ? 19 SER B C 1 ATOM 4899 O O . SER B 1 19 ? 23.569 43.944 59.668 1.00 10.30 ? 19 SER B O 1 ATOM 4900 C CB . SER B 1 19 ? 21.417 41.770 60.160 1.00 16.74 ? 19 SER B CB 1 ATOM 4901 O OG . SER B 1 19 ? 22.396 40.742 60.132 1.00 17.28 ? 19 SER B OG 1 ATOM 4902 N N . PRO B 1 20 ? 24.294 42.746 61.418 1.00 10.11 ? 20 PRO B N 1 ATOM 4903 C CA . PRO B 1 20 ? 25.720 42.966 61.160 1.00 10.25 ? 20 PRO B CA 1 ATOM 4904 C C . PRO B 1 20 ? 26.237 41.977 60.116 1.00 9.57 ? 20 PRO B C 1 ATOM 4905 O O . PRO B 1 20 ? 27.454 41.822 59.968 1.00 10.06 ? 20 PRO B O 1 ATOM 4906 C CB . PRO B 1 20 ? 26.381 42.695 62.519 1.00 10.37 ? 20 PRO B CB 1 ATOM 4907 C CG . PRO B 1 20 ? 25.273 42.850 63.515 1.00 11.56 ? 20 PRO B CG 1 ATOM 4908 C CD . PRO B 1 20 ? 24.090 42.251 62.789 1.00 11.57 ? 20 PRO B CD 1 ATOM 4909 N N . TYR B 1 21 ? 25.326 41.314 59.399 1.00 6.92 ? 21 TYR B N 1 ATOM 4910 C CA . TYR B 1 21 ? 25.729 40.309 58.417 1.00 3.51 ? 21 TYR B CA 1 ATOM 4911 C C . TYR B 1 21 ? 25.275 40.488 56.966 1.00 2.78 ? 21 TYR B C 1 ATOM 4912 O O . TYR B 1 21 ? 24.239 41.088 56.698 1.00 4.09 ? 21 TYR B O 1 ATOM 4913 C CB . TYR B 1 21 ? 25.306 38.936 58.938 1.00 2.35 ? 21 TYR B CB 1 ATOM 4914 C CG . TYR B 1 21 ? 25.911 38.621 60.293 1.00 2.43 ? 21 TYR B CG 1 ATOM 4915 C CD1 . TYR B 1 21 ? 27.287 38.692 60.491 1.00 2.96 ? 21 TYR B CD1 1 ATOM 4916 C CD2 . TYR B 1 21 ? 25.114 38.274 61.379 1.00 2.71 ? 21 TYR B CD2 1 ATOM 4917 C CE1 . TYR B 1 21 ? 27.857 38.429 61.729 1.00 2.30 ? 21 TYR B CE1 1 ATOM 4918 C CE2 . TYR B 1 21 ? 25.676 38.008 62.630 1.00 2.46 ? 21 TYR B CE2 1 ATOM 4919 C CZ . TYR B 1 21 ? 27.054 38.086 62.794 1.00 2.50 ? 21 TYR B CZ 1 ATOM 4920 O OH . TYR B 1 21 ? 27.645 37.806 64.009 1.00 2.75 ? 21 TYR B OH 1 ATOM 4921 N N . ARG B 1 22 ? 26.077 39.959 56.040 1.00 2.87 ? 22 ARG B N 1 ATOM 4922 C CA . ARG B 1 22 ? 25.812 40.020 54.592 1.00 3.56 ? 22 ARG B CA 1 ATOM 4923 C C . ARG B 1 22 ? 24.740 39.014 54.157 1.00 2.62 ? 22 ARG B C 1 ATOM 4924 O O . ARG B 1 22 ? 24.732 37.880 54.636 1.00 3.04 ? 22 ARG B O 1 ATOM 4925 C CB . ARG B 1 22 ? 27.081 39.672 53.791 1.00 3.47 ? 22 ARG B CB 1 ATOM 4926 C CG . ARG B 1 22 ? 28.173 40.734 53.658 1.00 3.07 ? 22 ARG B CG 1 ATOM 4927 C CD . ARG B 1 22 ? 29.320 40.190 52.784 1.00 2.00 ? 22 ARG B CD 1 ATOM 4928 N NE . ARG B 1 22 ? 30.407 41.147 52.565 1.00 2.05 ? 22 ARG B NE 1 ATOM 4929 C CZ . ARG B 1 22 ? 30.338 42.193 51.747 1.00 2.00 ? 22 ARG B CZ 1 ATOM 4930 N NH1 . ARG B 1 22 ? 29.233 42.422 51.059 1.00 2.00 ? 22 ARG B NH1 1 ATOM 4931 N NH2 . ARG B 1 22 ? 31.368 43.017 51.625 1.00 2.00 ? 22 ARG B NH2 1 ATOM 4932 N N . THR B 1 23 ? 23.856 39.403 53.240 1.00 2.00 ? 23 THR B N 1 ATOM 4933 C CA . THR B 1 23 ? 22.849 38.455 52.770 1.00 2.20 ? 23 THR B CA 1 ATOM 4934 C C . THR B 1 23 ? 23.538 37.621 51.704 1.00 2.79 ? 23 THR B C 1 ATOM 4935 O O . THR B 1 23 ? 24.566 38.022 51.169 1.00 2.56 ? 23 THR B O 1 ATOM 4936 C CB . THR B 1 23 ? 21.653 39.125 52.094 1.00 2.00 ? 23 THR B CB 1 ATOM 4937 O OG1 . THR B 1 23 ? 21.974 39.400 50.725 1.00 2.00 ? 23 THR B OG1 1 ATOM 4938 C CG2 . THR B 1 23 ? 21.306 40.411 52.786 1.00 3.46 ? 23 THR B CG2 1 ATOM 4939 N N . ILE B 1 24 ? 22.968 36.464 51.394 1.00 4.17 ? 24 ILE B N 1 ATOM 4940 C CA . ILE B 1 24 ? 23.532 35.581 50.378 1.00 2.17 ? 24 ILE B CA 1 ATOM 4941 C C . ILE B 1 24 ? 23.305 36.184 48.994 1.00 2.62 ? 24 ILE B C 1 ATOM 4942 O O . ILE B 1 24 ? 24.252 36.437 48.255 1.00 2.59 ? 24 ILE B O 1 ATOM 4943 C CB . ILE B 1 24 ? 22.879 34.181 50.452 1.00 2.30 ? 24 ILE B CB 1 ATOM 4944 C CG1 . ILE B 1 24 ? 23.386 33.440 51.696 1.00 2.29 ? 24 ILE B CG1 1 ATOM 4945 C CG2 . ILE B 1 24 ? 23.149 33.402 49.175 1.00 2.00 ? 24 ILE B CG2 1 ATOM 4946 C CD1 . ILE B 1 24 ? 24.882 33.207 51.716 1.00 2.00 ? 24 ILE B CD1 1 ATOM 4947 N N . THR B 1 25 ? 22.035 36.404 48.662 1.00 3.13 ? 25 THR B N 1 ATOM 4948 C CA . THR B 1 25 ? 21.620 36.991 47.394 1.00 2.25 ? 25 THR B CA 1 ATOM 4949 C C . THR B 1 25 ? 22.433 38.247 47.076 1.00 3.30 ? 25 THR B C 1 ATOM 4950 O O . THR B 1 25 ? 22.702 38.552 45.915 1.00 2.32 ? 25 THR B O 1 ATOM 4951 C CB . THR B 1 25 ? 20.124 37.349 47.451 1.00 3.45 ? 25 THR B CB 1 ATOM 4952 O OG1 . THR B 1 25 ? 19.793 38.247 46.383 1.00 6.19 ? 25 THR B OG1 1 ATOM 4953 C CG2 . THR B 1 25 ? 19.793 37.997 48.784 1.00 2.69 ? 25 THR B CG2 1 ATOM 4954 N N . GLY B 1 26 ? 22.822 38.982 48.110 1.00 3.58 ? 26 GLY B N 1 ATOM 4955 C CA . GLY B 1 26 ? 23.618 40.178 47.884 1.00 4.41 ? 26 GLY B CA 1 ATOM 4956 C C . GLY B 1 26 ? 22.860 41.468 48.116 1.00 4.29 ? 26 GLY B C 1 ATOM 4957 O O . GLY B 1 26 ? 23.437 42.557 48.109 1.00 4.14 ? 26 GLY B O 1 ATOM 4958 N N . ASP B 1 27 ? 21.558 41.330 48.330 1.00 3.31 ? 27 ASP B N 1 ATOM 4959 C CA . ASP B 1 27 ? 20.685 42.462 48.570 1.00 2.50 ? 27 ASP B CA 1 ATOM 4960 C C . ASP B 1 27 ? 21.005 43.228 49.840 1.00 2.07 ? 27 ASP B C 1 ATOM 4961 O O . ASP B 1 27 ? 21.808 42.801 50.668 1.00 2.00 ? 27 ASP B O 1 ATOM 4962 C CB . ASP B 1 27 ? 19.237 41.983 48.653 1.00 2.52 ? 27 ASP B CB 1 ATOM 4963 C CG . ASP B 1 27 ? 18.631 41.720 47.294 1.00 4.30 ? 27 ASP B CG 1 ATOM 4964 O OD1 . ASP B 1 27 ? 18.446 42.705 46.544 1.00 6.08 ? 27 ASP B OD1 1 ATOM 4965 O OD2 . ASP B 1 27 ? 18.342 40.542 46.972 1.00 3.32 ? 27 ASP B OD2 1 ATOM 4966 N N . CYS B 1 28 ? 20.366 44.387 49.950 1.00 4.90 ? 28 CYS B N 1 ATOM 4967 C CA . CYS B 1 28 ? 20.442 45.256 51.114 1.00 5.31 ? 28 CYS B CA 1 ATOM 4968 C C . CYS B 1 28 ? 21.742 45.914 51.458 1.00 3.08 ? 28 CYS B C 1 ATOM 4969 O O . CYS B 1 28 ? 21.800 46.699 52.399 1.00 2.00 ? 28 CYS B O 1 ATOM 4970 C CB . CYS B 1 28 ? 19.936 44.479 52.311 1.00 11.07 ? 28 CYS B CB 1 ATOM 4971 S SG . CYS B 1 28 ? 18.484 43.513 51.804 1.00 20.36 ? 28 CYS B SG 1 ATOM 4972 N N . ASN B 1 29 ? 22.790 45.601 50.716 1.00 3.49 ? 29 ASN B N 1 ATOM 4973 C CA . ASN B 1 29 ? 24.067 46.235 50.990 1.00 4.72 ? 29 ASN B CA 1 ATOM 4974 C C . ASN B 1 29 ? 23.765 47.736 50.938 1.00 2.95 ? 29 ASN B C 1 ATOM 4975 O O . ASN B 1 29 ? 24.346 48.544 51.666 1.00 3.00 ? 29 ASN B O 1 ATOM 4976 C CB . ASN B 1 29 ? 25.091 45.822 49.919 1.00 3.38 ? 29 ASN B CB 1 ATOM 4977 C CG . ASN B 1 29 ? 26.439 46.483 50.109 1.00 3.37 ? 29 ASN B CG 1 ATOM 4978 O OD1 . ASN B 1 29 ? 26.562 47.698 49.993 1.00 6.23 ? 29 ASN B OD1 1 ATOM 4979 N ND2 . ASN B 1 29 ? 27.457 45.689 50.398 1.00 2.00 ? 29 ASN B ND2 1 ATOM 4980 N N . ASN B 1 30 ? 22.792 48.080 50.101 1.00 3.60 ? 30 ASN B N 1 ATOM 4981 C CA . ASN B 1 30 ? 22.384 49.460 49.912 1.00 2.97 ? 30 ASN B CA 1 ATOM 4982 C C . ASN B 1 30 ? 20.975 49.772 50.443 1.00 4.06 ? 30 ASN B C 1 ATOM 4983 O O . ASN B 1 30 ? 19.988 49.137 50.063 1.00 3.76 ? 30 ASN B O 1 ATOM 4984 C CB . ASN B 1 30 ? 22.464 49.790 48.433 1.00 2.53 ? 30 ASN B CB 1 ATOM 4985 C CG . ASN B 1 30 ? 22.166 51.222 48.155 1.00 2.56 ? 30 ASN B CG 1 ATOM 4986 O OD1 . ASN B 1 30 ? 21.124 51.732 48.558 1.00 5.28 ? 30 ASN B OD1 1 ATOM 4987 N ND2 . ASN B 1 30 ? 23.076 51.894 47.460 1.00 2.00 ? 30 ASN B ND2 1 ATOM 4988 N N . ARG B 1 31 ? 20.891 50.775 51.310 1.00 4.81 ? 31 ARG B N 1 ATOM 4989 C CA . ARG B 1 31 ? 19.623 51.163 51.902 1.00 5.10 ? 31 ARG B CA 1 ATOM 4990 C C . ARG B 1 31 ? 18.661 51.875 50.936 1.00 7.94 ? 31 ARG B C 1 ATOM 4991 O O . ARG B 1 31 ? 17.464 51.574 50.932 1.00 8.35 ? 31 ARG B O 1 ATOM 4992 C CB . ARG B 1 31 ? 19.886 52.005 53.166 1.00 5.71 ? 31 ARG B CB 1 ATOM 4993 C CG . ARG B 1 31 ? 20.346 51.151 54.363 1.00 5.68 ? 31 ARG B CG 1 ATOM 4994 C CD . ARG B 1 31 ? 20.810 51.935 55.605 1.00 5.31 ? 31 ARG B CD 1 ATOM 4995 N NE . ARG B 1 31 ? 20.867 51.052 56.780 1.00 7.89 ? 31 ARG B NE 1 ATOM 4996 C CZ . ARG B 1 31 ? 21.841 51.043 57.693 1.00 9.01 ? 31 ARG B CZ 1 ATOM 4997 N NH1 . ARG B 1 31 ? 22.869 51.876 57.584 1.00 9.95 ? 31 ARG B NH1 1 ATOM 4998 N NH2 . ARG B 1 31 ? 21.796 50.189 58.715 1.00 7.08 ? 31 ARG B NH2 1 ATOM 4999 N N . ARG B 1 32 ? 19.151 52.798 50.106 1.00 8.93 ? 32 ARG B N 1 ATOM 5000 C CA . ARG B 1 32 ? 18.244 53.478 49.177 1.00 9.56 ? 32 ARG B CA 1 ATOM 5001 C C . ARG B 1 32 ? 17.841 52.633 47.973 1.00 8.63 ? 32 ARG B C 1 ATOM 5002 O O . ARG B 1 32 ? 16.761 52.815 47.419 1.00 9.57 ? 32 ARG B O 1 ATOM 5003 C CB . ARG B 1 32 ? 18.820 54.821 48.702 1.00 12.74 ? 32 ARG B CB 1 ATOM 5004 C CG . ARG B 1 32 ? 18.238 56.010 49.492 1.00 18.80 ? 32 ARG B CG 1 ATOM 5005 C CD . ARG B 1 32 ? 18.406 57.381 48.812 1.00 20.99 ? 32 ARG B CD 1 ATOM 5006 N NE . ARG B 1 32 ? 19.361 58.254 49.502 1.00 23.27 ? 32 ARG B NE 1 ATOM 5007 C CZ . ARG B 1 32 ? 20.635 58.397 49.147 1.00 24.17 ? 32 ARG B CZ 1 ATOM 5008 N NH1 . ARG B 1 32 ? 21.120 57.727 48.105 1.00 24.57 ? 32 ARG B NH1 1 ATOM 5009 N NH2 . ARG B 1 32 ? 21.426 59.212 49.830 1.00 25.47 ? 32 ARG B NH2 1 ATOM 5010 N N . SER B 1 33 ? 18.702 51.707 47.575 1.00 7.43 ? 33 SER B N 1 ATOM 5011 C CA . SER B 1 33 ? 18.419 50.832 46.447 1.00 6.88 ? 33 SER B CA 1 ATOM 5012 C C . SER B 1 33 ? 18.980 49.474 46.825 1.00 6.82 ? 33 SER B C 1 ATOM 5013 O O . SER B 1 33 ? 20.165 49.207 46.649 1.00 7.43 ? 33 SER B O 1 ATOM 5014 C CB . SER B 1 33 ? 19.100 51.355 45.189 1.00 6.76 ? 33 SER B CB 1 ATOM 5015 O OG . SER B 1 33 ? 18.198 51.349 44.099 1.00 9.11 ? 33 SER B OG 1 ATOM 5016 N N . PRO B 1 34 ? 18.126 48.599 47.363 1.00 6.37 ? 34 PRO B N 1 ATOM 5017 C CA . PRO B 1 34 ? 18.423 47.232 47.820 1.00 5.82 ? 34 PRO B CA 1 ATOM 5018 C C . PRO B 1 34 ? 19.056 46.297 46.790 1.00 5.71 ? 34 PRO B C 1 ATOM 5019 O O . PRO B 1 34 ? 20.230 45.946 46.905 1.00 6.02 ? 34 PRO B O 1 ATOM 5020 C CB . PRO B 1 34 ? 17.065 46.726 48.296 1.00 7.03 ? 34 PRO B CB 1 ATOM 5021 C CG . PRO B 1 34 ? 16.338 48.012 48.683 1.00 8.63 ? 34 PRO B CG 1 ATOM 5022 C CD . PRO B 1 34 ? 16.702 48.918 47.547 1.00 6.83 ? 34 PRO B CD 1 ATOM 5023 N N . ALA B 1 35 ? 18.271 45.891 45.796 1.00 3.68 ? 35 ALA B N 1 ATOM 5024 C CA . ALA B 1 35 ? 18.738 44.994 44.739 1.00 3.31 ? 35 ALA B CA 1 ATOM 5025 C C . ALA B 1 35 ? 19.965 45.501 43.984 1.00 4.39 ? 35 ALA B C 1 ATOM 5026 O O . ALA B 1 35 ? 20.469 44.822 43.085 1.00 5.13 ? 35 ALA B O 1 ATOM 5027 C CB . ALA B 1 35 ? 17.617 44.740 43.754 1.00 2.54 ? 35 ALA B CB 1 ATOM 5028 N N . LEU B 1 36 ? 20.439 46.691 44.332 1.00 4.37 ? 36 LEU B N 1 ATOM 5029 C CA . LEU B 1 36 ? 21.604 47.262 43.669 1.00 2.39 ? 36 LEU B CA 1 ATOM 5030 C C . LEU B 1 36 ? 22.866 46.525 44.063 1.00 3.09 ? 36 LEU B C 1 ATOM 5031 O O . LEU B 1 36 ? 23.380 46.704 45.168 1.00 2.00 ? 36 LEU B O 1 ATOM 5032 C CB . LEU B 1 36 ? 21.772 48.731 44.039 1.00 3.56 ? 36 LEU B CB 1 ATOM 5033 C CG . LEU B 1 36 ? 22.988 49.394 43.395 1.00 3.46 ? 36 LEU B CG 1 ATOM 5034 C CD1 . LEU B 1 36 ? 22.556 50.103 42.113 1.00 3.75 ? 36 LEU B CD1 1 ATOM 5035 C CD2 . LEU B 1 36 ? 23.610 50.378 44.370 1.00 3.10 ? 36 LEU B CD2 1 ATOM 5036 N N . GLY B 1 37 ? 23.361 45.693 43.153 1.00 5.54 ? 37 GLY B N 1 ATOM 5037 C CA . GLY B 1 37 ? 24.583 44.956 43.417 1.00 4.26 ? 37 GLY B CA 1 ATOM 5038 C C . GLY B 1 37 ? 24.395 43.486 43.720 1.00 4.30 ? 37 GLY B C 1 ATOM 5039 O O . GLY B 1 37 ? 25.377 42.779 43.954 1.00 5.17 ? 37 GLY B O 1 ATOM 5040 N N . ALA B 1 38 ? 23.150 43.015 43.710 1.00 4.26 ? 38 ALA B N 1 ATOM 5041 C CA . ALA B 1 38 ? 22.879 41.612 44.001 1.00 3.55 ? 38 ALA B CA 1 ATOM 5042 C C . ALA B 1 38 ? 22.988 40.729 42.765 1.00 2.91 ? 38 ALA B C 1 ATOM 5043 O O . ALA B 1 38 ? 23.048 41.214 41.639 1.00 2.89 ? 38 ALA B O 1 ATOM 5044 C CB . ALA B 1 38 ? 21.503 41.466 44.628 1.00 3.79 ? 38 ALA B CB 1 ATOM 5045 N N . ALA B 1 39 ? 23.014 39.423 42.994 1.00 3.55 ? 39 ALA B N 1 ATOM 5046 C CA . ALA B 1 39 ? 23.120 38.455 41.918 1.00 2.00 ? 39 ALA B CA 1 ATOM 5047 C C . ALA B 1 39 ? 21.845 38.349 41.094 1.00 2.23 ? 39 ALA B C 1 ATOM 5048 O O . ALA B 1 39 ? 20.748 38.635 41.572 1.00 2.40 ? 39 ALA B O 1 ATOM 5049 C CB . ALA B 1 39 ? 23.483 37.096 42.484 1.00 2.00 ? 39 ALA B CB 1 ATOM 5050 N N . ASN B 1 40 ? 22.021 37.921 39.848 1.00 4.01 ? 40 ASN B N 1 ATOM 5051 C CA . ASN B 1 40 ? 20.943 37.744 38.880 1.00 4.64 ? 40 ASN B CA 1 ATOM 5052 C C . ASN B 1 40 ? 20.326 39.016 38.339 1.00 4.29 ? 40 ASN B C 1 ATOM 5053 O O . ASN B 1 40 ? 19.129 39.049 38.068 1.00 5.00 ? 40 ASN B O 1 ATOM 5054 C CB . ASN B 1 40 ? 19.835 36.863 39.445 1.00 5.69 ? 40 ASN B CB 1 ATOM 5055 C CG . ASN B 1 40 ? 20.289 35.446 39.664 1.00 7.46 ? 40 ASN B CG 1 ATOM 5056 O OD1 . ASN B 1 40 ? 20.724 34.768 38.732 1.00 7.37 ? 40 ASN B OD1 1 ATOM 5057 N ND2 . ASN B 1 40 ? 20.194 34.985 40.905 1.00 10.69 ? 40 ASN B ND2 1 ATOM 5058 N N . ARG B 1 41 ? 21.135 40.061 38.197 1.00 4.34 ? 41 ARG B N 1 ATOM 5059 C CA . ARG B 1 41 ? 20.660 41.315 37.626 1.00 4.92 ? 41 ARG B CA 1 ATOM 5060 C C . ARG B 1 41 ? 21.613 41.633 36.473 1.00 5.20 ? 41 ARG B C 1 ATOM 5061 O O . ARG B 1 41 ? 22.791 41.282 36.518 1.00 6.61 ? 41 ARG B O 1 ATOM 5062 C CB . ARG B 1 41 ? 20.703 42.438 38.651 1.00 5.73 ? 41 ARG B CB 1 ATOM 5063 C CG . ARG B 1 41 ? 20.053 42.101 39.968 1.00 10.37 ? 41 ARG B CG 1 ATOM 5064 C CD . ARG B 1 41 ? 18.552 41.961 39.855 1.00 11.78 ? 41 ARG B CD 1 ATOM 5065 N NE . ARG B 1 41 ? 17.985 41.657 41.163 1.00 14.39 ? 41 ARG B NE 1 ATOM 5066 C CZ . ARG B 1 41 ? 16.978 42.323 41.716 1.00 16.06 ? 41 ARG B CZ 1 ATOM 5067 N NH1 . ARG B 1 41 ? 16.417 43.338 41.069 1.00 16.39 ? 41 ARG B NH1 1 ATOM 5068 N NH2 . ARG B 1 41 ? 16.538 41.980 42.922 1.00 17.76 ? 41 ARG B NH2 1 ATOM 5069 N N . ALA B 1 42 ? 21.107 42.289 35.438 1.00 4.30 ? 42 ALA B N 1 ATOM 5070 C CA . ALA B 1 42 ? 21.929 42.625 34.290 1.00 2.38 ? 42 ALA B CA 1 ATOM 5071 C C . ALA B 1 42 ? 23.219 43.322 34.665 1.00 2.00 ? 42 ALA B C 1 ATOM 5072 O O . ALA B 1 42 ? 23.248 44.137 35.578 1.00 2.00 ? 42 ALA B O 1 ATOM 5073 C CB . ALA B 1 42 ? 21.153 43.504 33.351 1.00 3.41 ? 42 ALA B CB 1 ATOM 5074 N N . LEU B 1 43 ? 24.283 42.991 33.944 1.00 2.00 ? 43 LEU B N 1 ATOM 5075 C CA . LEU B 1 43 ? 25.585 43.615 34.141 1.00 2.00 ? 43 LEU B CA 1 ATOM 5076 C C . LEU B 1 43 ? 25.363 45.090 33.792 1.00 2.06 ? 43 LEU B C 1 ATOM 5077 O O . LEU B 1 43 ? 24.473 45.413 33.004 1.00 3.73 ? 43 LEU B O 1 ATOM 5078 C CB . LEU B 1 43 ? 26.605 43.009 33.168 1.00 2.08 ? 43 LEU B CB 1 ATOM 5079 C CG . LEU B 1 43 ? 26.871 41.501 33.167 1.00 2.00 ? 43 LEU B CG 1 ATOM 5080 C CD1 . LEU B 1 43 ? 27.290 41.046 31.790 1.00 2.00 ? 43 LEU B CD1 1 ATOM 5081 C CD2 . LEU B 1 43 ? 27.942 41.179 34.175 1.00 2.00 ? 43 LEU B CD2 1 ATOM 5082 N N . ALA B 1 44 ? 26.155 45.989 34.364 1.00 2.38 ? 44 ALA B N 1 ATOM 5083 C CA . ALA B 1 44 ? 25.985 47.412 34.068 1.00 2.99 ? 44 ALA B CA 1 ATOM 5084 C C . ALA B 1 44 ? 26.724 47.816 32.796 1.00 2.72 ? 44 ALA B C 1 ATOM 5085 O O . ALA B 1 44 ? 27.653 47.139 32.362 1.00 3.12 ? 44 ALA B O 1 ATOM 5086 C CB . ALA B 1 44 ? 26.466 48.254 35.243 1.00 3.76 ? 44 ALA B CB 1 ATOM 5087 N N . ARG B 1 45 ? 26.317 48.928 32.205 1.00 2.00 ? 45 ARG B N 1 ATOM 5088 C CA . ARG B 1 45 ? 26.948 49.386 30.982 1.00 2.00 ? 45 ARG B CA 1 ATOM 5089 C C . ARG B 1 45 ? 27.572 50.740 31.171 1.00 2.00 ? 45 ARG B C 1 ATOM 5090 O O . ARG B 1 45 ? 26.870 51.691 31.481 1.00 4.21 ? 45 ARG B O 1 ATOM 5091 C CB . ARG B 1 45 ? 25.912 49.513 29.885 1.00 2.00 ? 45 ARG B CB 1 ATOM 5092 C CG . ARG B 1 45 ? 25.239 48.239 29.513 1.00 2.49 ? 45 ARG B CG 1 ATOM 5093 C CD . ARG B 1 45 ? 25.861 47.686 28.268 1.00 2.12 ? 45 ARG B CD 1 ATOM 5094 N NE . ARG B 1 45 ? 25.170 46.481 27.846 1.00 2.94 ? 45 ARG B NE 1 ATOM 5095 C CZ . ARG B 1 45 ? 25.585 45.707 26.857 1.00 2.42 ? 45 ARG B CZ 1 ATOM 5096 N NH1 . ARG B 1 45 ? 26.689 46.021 26.195 1.00 2.00 ? 45 ARG B NH1 1 ATOM 5097 N NH2 . ARG B 1 45 ? 24.896 44.624 26.535 1.00 3.40 ? 45 ARG B NH2 1 ATOM 5098 N N . TRP B 1 46 ? 28.878 50.853 30.988 1.00 2.00 ? 46 TRP B N 1 ATOM 5099 C CA . TRP B 1 46 ? 29.484 52.163 31.125 1.00 2.00 ? 46 TRP B CA 1 ATOM 5100 C C . TRP B 1 46 ? 29.307 52.877 29.794 1.00 2.00 ? 46 TRP B C 1 ATOM 5101 O O . TRP B 1 46 ? 29.219 54.100 29.753 1.00 3.14 ? 46 TRP B O 1 ATOM 5102 C CB . TRP B 1 46 ? 30.962 52.059 31.481 1.00 2.11 ? 46 TRP B CB 1 ATOM 5103 C CG . TRP B 1 46 ? 31.220 51.509 32.851 1.00 2.00 ? 46 TRP B CG 1 ATOM 5104 C CD1 . TRP B 1 46 ? 30.316 51.356 33.864 1.00 2.00 ? 46 TRP B CD1 1 ATOM 5105 C CD2 . TRP B 1 46 ? 32.483 51.092 33.375 1.00 2.31 ? 46 TRP B CD2 1 ATOM 5106 N NE1 . TRP B 1 46 ? 30.942 50.873 34.992 1.00 2.00 ? 46 TRP B NE1 1 ATOM 5107 C CE2 . TRP B 1 46 ? 32.273 50.704 34.718 1.00 2.00 ? 46 TRP B CE2 1 ATOM 5108 C CE3 . TRP B 1 46 ? 33.778 51.013 32.840 1.00 2.00 ? 46 TRP B CE3 1 ATOM 5109 C CZ2 . TRP B 1 46 ? 33.305 50.243 35.533 1.00 2.14 ? 46 TRP B CZ2 1 ATOM 5110 C CZ3 . TRP B 1 46 ? 34.808 50.554 33.652 1.00 2.00 ? 46 TRP B CZ3 1 ATOM 5111 C CH2 . TRP B 1 46 ? 34.564 50.175 34.986 1.00 2.39 ? 46 TRP B CH2 1 ATOM 5112 N N . LEU B 1 47 ? 29.248 52.108 28.707 1.00 2.00 ? 47 LEU B N 1 ATOM 5113 C CA . LEU B 1 47 ? 29.043 52.668 27.366 1.00 2.00 ? 47 LEU B CA 1 ATOM 5114 C C . LEU B 1 47 ? 27.928 51.927 26.612 1.00 2.00 ? 47 LEU B C 1 ATOM 5115 O O . LEU B 1 47 ? 27.842 50.703 26.659 1.00 2.00 ? 47 LEU B O 1 ATOM 5116 C CB . LEU B 1 47 ? 30.340 52.633 26.549 1.00 2.00 ? 47 LEU B CB 1 ATOM 5117 C CG . LEU B 1 47 ? 31.391 53.717 26.792 1.00 2.00 ? 47 LEU B CG 1 ATOM 5118 C CD1 . LEU B 1 47 ? 32.458 53.626 25.727 1.00 2.00 ? 47 LEU B CD1 1 ATOM 5119 C CD2 . LEU B 1 47 ? 30.754 55.078 26.742 1.00 2.00 ? 47 LEU B CD2 1 ATOM 5120 N N . PRO B 1 48 ? 27.066 52.666 25.899 1.00 2.00 ? 48 PRO B N 1 ATOM 5121 C CA . PRO B 1 48 ? 25.954 52.089 25.143 1.00 2.00 ? 48 PRO B CA 1 ATOM 5122 C C . PRO B 1 48 ? 26.327 50.874 24.325 1.00 2.00 ? 48 PRO B C 1 ATOM 5123 O O . PRO B 1 48 ? 27.367 50.843 23.669 1.00 2.52 ? 48 PRO B O 1 ATOM 5124 C CB . PRO B 1 48 ? 25.490 53.249 24.278 1.00 2.40 ? 48 PRO B CB 1 ATOM 5125 C CG . PRO B 1 48 ? 25.761 54.424 25.150 1.00 2.77 ? 48 PRO B CG 1 ATOM 5126 C CD . PRO B 1 48 ? 27.151 54.112 25.650 1.00 2.72 ? 48 PRO B CD 1 ATOM 5127 N N . ALA B 1 49 ? 25.446 49.881 24.370 1.00 2.00 ? 49 ALA B N 1 ATOM 5128 C CA . ALA B 1 49 ? 25.626 48.622 23.670 1.00 2.00 ? 49 ALA B CA 1 ATOM 5129 C C . ALA B 1 49 ? 25.772 48.797 22.177 1.00 2.00 ? 49 ALA B C 1 ATOM 5130 O O . ALA B 1 49 ? 25.120 49.636 21.569 1.00 2.28 ? 49 ALA B O 1 ATOM 5131 C CB . ALA B 1 49 ? 24.458 47.708 23.963 1.00 2.00 ? 49 ALA B CB 1 ATOM 5132 N N . GLU B 1 50 ? 26.628 47.991 21.577 1.00 2.00 ? 50 GLU B N 1 ATOM 5133 C CA . GLU B 1 50 ? 26.816 48.091 20.150 1.00 2.00 ? 50 GLU B CA 1 ATOM 5134 C C . GLU B 1 50 ? 26.536 46.786 19.430 1.00 2.00 ? 50 GLU B C 1 ATOM 5135 O O . GLU B 1 50 ? 27.399 45.932 19.325 1.00 3.51 ? 50 GLU B O 1 ATOM 5136 C CB . GLU B 1 50 ? 28.227 48.594 19.840 1.00 2.00 ? 50 GLU B CB 1 ATOM 5137 C CG . GLU B 1 50 ? 28.430 50.051 20.239 1.00 2.00 ? 50 GLU B CG 1 ATOM 5138 C CD . GLU B 1 50 ? 29.666 50.658 19.619 1.00 2.11 ? 50 GLU B CD 1 ATOM 5139 O OE1 . GLU B 1 50 ? 30.271 49.998 18.744 1.00 3.07 ? 50 GLU B OE1 1 ATOM 5140 O OE2 . GLU B 1 50 ? 30.022 51.797 19.998 1.00 2.02 ? 50 GLU B OE2 1 ATOM 5141 N N . TYR B 1 51 ? 25.303 46.633 18.959 1.00 3.25 ? 51 TYR B N 1 ATOM 5142 C CA . TYR B 1 51 ? 24.894 45.449 18.210 1.00 2.33 ? 51 TYR B CA 1 ATOM 5143 C C . TYR B 1 51 ? 24.660 45.851 16.754 1.00 2.00 ? 51 TYR B C 1 ATOM 5144 O O . TYR B 1 51 ? 24.446 47.023 16.452 1.00 2.00 ? 51 TYR B O 1 ATOM 5145 C CB . TYR B 1 51 ? 23.594 44.862 18.764 1.00 2.00 ? 51 TYR B CB 1 ATOM 5146 C CG . TYR B 1 51 ? 23.709 44.218 20.111 1.00 2.00 ? 51 TYR B CG 1 ATOM 5147 C CD1 . TYR B 1 51 ? 24.591 43.171 20.324 1.00 2.00 ? 51 TYR B CD1 1 ATOM 5148 C CD2 . TYR B 1 51 ? 22.921 44.647 21.173 1.00 2.00 ? 51 TYR B CD2 1 ATOM 5149 C CE1 . TYR B 1 51 ? 24.692 42.557 21.571 1.00 2.61 ? 51 TYR B CE1 1 ATOM 5150 C CE2 . TYR B 1 51 ? 23.008 44.046 22.425 1.00 2.13 ? 51 TYR B CE2 1 ATOM 5151 C CZ . TYR B 1 51 ? 23.898 43.000 22.617 1.00 2.52 ? 51 TYR B CZ 1 ATOM 5152 O OH . TYR B 1 51 ? 24.004 42.399 23.850 1.00 3.89 ? 51 TYR B OH 1 ATOM 5153 N N . GLU B 1 52 ? 24.688 44.860 15.867 1.00 3.99 ? 52 GLU B N 1 ATOM 5154 C CA . GLU B 1 52 ? 24.485 45.053 14.433 1.00 4.77 ? 52 GLU B CA 1 ATOM 5155 C C . GLU B 1 52 ? 23.138 45.699 14.099 1.00 5.19 ? 52 GLU B C 1 ATOM 5156 O O . GLU B 1 52 ? 23.089 46.686 13.352 1.00 6.07 ? 52 GLU B O 1 ATOM 5157 C CB . GLU B 1 52 ? 24.628 43.706 13.727 1.00 5.49 ? 52 GLU B CB 1 ATOM 5158 C CG . GLU B 1 52 ? 23.843 43.556 12.450 1.00 9.32 ? 52 GLU B CG 1 ATOM 5159 C CD . GLU B 1 52 ? 24.143 42.242 11.754 1.00 11.87 ? 52 GLU B CD 1 ATOM 5160 O OE1 . GLU B 1 52 ? 23.298 41.783 10.952 1.00 13.40 ? 52 GLU B OE1 1 ATOM 5161 O OE2 . GLU B 1 52 ? 25.231 41.673 12.002 1.00 13.10 ? 52 GLU B OE2 1 ATOM 5162 N N . ASP B 1 53 ? 22.051 45.140 14.632 1.00 4.79 ? 53 ASP B N 1 ATOM 5163 C CA . ASP B 1 53 ? 20.723 45.707 14.404 1.00 3.43 ? 53 ASP B CA 1 ATOM 5164 C C . ASP B 1 53 ? 20.527 46.765 15.478 1.00 3.05 ? 53 ASP B C 1 ATOM 5165 O O . ASP B 1 53 ? 19.405 47.108 15.838 1.00 3.87 ? 53 ASP B O 1 ATOM 5166 C CB . ASP B 1 53 ? 19.622 44.629 14.490 1.00 3.49 ? 53 ASP B CB 1 ATOM 5167 C CG . ASP B 1 53 ? 19.524 43.977 15.866 1.00 2.58 ? 53 ASP B CG 1 ATOM 5168 O OD1 . ASP B 1 53 ? 20.421 44.207 16.699 1.00 2.00 ? 53 ASP B OD1 1 ATOM 5169 O OD2 . ASP B 1 53 ? 18.553 43.219 16.108 1.00 2.00 ? 53 ASP B OD2 1 ATOM 5170 N N . GLY B 1 54 ? 21.654 47.265 15.983 1.00 3.39 ? 54 GLY B N 1 ATOM 5171 C CA . GLY B 1 54 ? 21.656 48.284 17.017 1.00 2.39 ? 54 GLY B CA 1 ATOM 5172 C C . GLY B 1 54 ? 20.919 47.858 18.273 1.00 2.48 ? 54 GLY B C 1 ATOM 5173 O O . GLY B 1 54 ? 21.065 48.478 19.324 1.00 2.28 ? 54 GLY B O 1 ATOM 5174 N N . LEU B 1 55 ? 20.162 46.770 18.176 1.00 2.00 ? 55 LEU B N 1 ATOM 5175 C CA . LEU B 1 55 ? 19.358 46.296 19.293 1.00 3.25 ? 55 LEU B CA 1 ATOM 5176 C C . LEU B 1 55 ? 19.791 44.992 20.012 1.00 5.06 ? 55 LEU B C 1 ATOM 5177 O O . LEU B 1 55 ? 19.855 44.956 21.249 1.00 4.03 ? 55 LEU B O 1 ATOM 5178 C CB . LEU B 1 55 ? 17.917 46.171 18.797 1.00 3.08 ? 55 LEU B CB 1 ATOM 5179 C CG . LEU B 1 55 ? 16.784 46.256 19.806 1.00 3.05 ? 55 LEU B CG 1 ATOM 5180 C CD1 . LEU B 1 55 ? 16.880 47.571 20.562 1.00 2.00 ? 55 LEU B CD1 1 ATOM 5181 C CD2 . LEU B 1 55 ? 15.456 46.134 19.068 1.00 2.00 ? 55 LEU B CD2 1 ATOM 5182 N N . ALA B 1 56 ? 20.080 43.928 19.261 1.00 4.14 ? 56 ALA B N 1 ATOM 5183 C CA . ALA B 1 56 ? 20.470 42.672 19.894 1.00 3.07 ? 56 ALA B CA 1 ATOM 5184 C C . ALA B 1 56 ? 21.295 41.625 19.104 1.00 3.89 ? 56 ALA B C 1 ATOM 5185 O O . ALA B 1 56 ? 21.751 40.654 19.711 1.00 3.12 ? 56 ALA B O 1 ATOM 5186 C CB . ALA B 1 56 ? 19.220 42.007 20.474 1.00 2.86 ? 56 ALA B CB 1 ATOM 5187 N N . VAL B 1 57 ? 21.488 41.776 17.788 1.00 3.27 ? 57 VAL B N 1 ATOM 5188 C CA . VAL B 1 57 ? 22.281 40.769 17.060 1.00 2.53 ? 57 VAL B CA 1 ATOM 5189 C C . VAL B 1 57 ? 23.728 41.207 16.993 1.00 2.00 ? 57 VAL B C 1 ATOM 5190 O O . VAL B 1 57 ? 24.024 42.352 16.669 1.00 2.00 ? 57 VAL B O 1 ATOM 5191 C CB . VAL B 1 57 ? 21.772 40.484 15.619 1.00 3.10 ? 57 VAL B CB 1 ATOM 5192 C CG1 . VAL B 1 57 ? 20.356 40.977 15.462 1.00 4.91 ? 57 VAL B CG1 1 ATOM 5193 C CG2 . VAL B 1 57 ? 22.705 41.093 14.585 1.00 3.83 ? 57 VAL B CG2 1 ATOM 5194 N N . PRO B 1 58 ? 24.649 40.281 17.285 1.00 2.00 ? 58 PRO B N 1 ATOM 5195 C CA . PRO B 1 58 ? 26.107 40.446 17.315 1.00 3.51 ? 58 PRO B CA 1 ATOM 5196 C C . PRO B 1 58 ? 26.775 40.782 15.999 1.00 3.42 ? 58 PRO B C 1 ATOM 5197 O O . PRO B 1 58 ? 26.300 40.395 14.939 1.00 5.48 ? 58 PRO B O 1 ATOM 5198 C CB . PRO B 1 58 ? 26.597 39.100 17.860 1.00 2.24 ? 58 PRO B CB 1 ATOM 5199 C CG . PRO B 1 58 ? 25.366 38.488 18.498 1.00 2.00 ? 58 PRO B CG 1 ATOM 5200 C CD . PRO B 1 58 ? 24.294 38.881 17.549 1.00 2.00 ? 58 PRO B CD 1 ATOM 5201 N N . PHE B 1 59 ? 27.887 41.501 16.058 1.00 3.74 ? 59 PHE B N 1 ATOM 5202 C CA . PHE B 1 59 ? 28.587 41.805 14.826 1.00 6.16 ? 59 PHE B CA 1 ATOM 5203 C C . PHE B 1 59 ? 29.298 40.564 14.308 1.00 7.63 ? 59 PHE B C 1 ATOM 5204 O O . PHE B 1 59 ? 30.151 39.998 14.984 1.00 9.49 ? 59 PHE B O 1 ATOM 5205 C CB . PHE B 1 59 ? 29.593 42.927 15.034 1.00 4.75 ? 59 PHE B CB 1 ATOM 5206 C CG . PHE B 1 59 ? 29.025 44.279 14.774 1.00 3.61 ? 59 PHE B CG 1 ATOM 5207 C CD1 . PHE B 1 59 ? 28.753 45.142 15.814 1.00 3.79 ? 59 PHE B CD1 1 ATOM 5208 C CD2 . PHE B 1 59 ? 28.717 44.672 13.479 1.00 3.32 ? 59 PHE B CD2 1 ATOM 5209 C CE1 . PHE B 1 59 ? 28.177 46.382 15.569 1.00 3.99 ? 59 PHE B CE1 1 ATOM 5210 C CE2 . PHE B 1 59 ? 28.142 45.907 13.226 1.00 2.83 ? 59 PHE B CE2 1 ATOM 5211 C CZ . PHE B 1 59 ? 27.872 46.761 14.270 1.00 3.32 ? 59 PHE B CZ 1 ATOM 5212 N N . GLY B 1 60 ? 28.947 40.143 13.102 1.00 9.40 ? 60 GLY B N 1 ATOM 5213 C CA . GLY B 1 60 ? 29.570 38.966 12.533 1.00 11.71 ? 60 GLY B CA 1 ATOM 5214 C C . GLY B 1 60 ? 28.497 37.916 12.407 1.00 13.56 ? 60 GLY B C 1 ATOM 5215 O O . GLY B 1 60 ? 28.768 36.724 12.265 1.00 15.59 ? 60 GLY B O 1 ATOM 5216 N N . TRP B 1 61 ? 27.257 38.381 12.452 1.00 14.43 ? 61 TRP B N 1 ATOM 5217 C CA . TRP B 1 61 ? 26.107 37.504 12.363 1.00 17.16 ? 61 TRP B CA 1 ATOM 5218 C C . TRP B 1 61 ? 25.567 37.347 10.957 1.00 19.82 ? 61 TRP B C 1 ATOM 5219 O O . TRP B 1 61 ? 25.533 36.240 10.420 1.00 22.10 ? 61 TRP B O 1 ATOM 5220 C CB . TRP B 1 61 ? 25.001 38.036 13.245 1.00 13.80 ? 61 TRP B CB 1 ATOM 5221 C CG . TRP B 1 61 ? 23.854 37.130 13.332 1.00 10.44 ? 61 TRP B CG 1 ATOM 5222 C CD1 . TRP B 1 61 ? 22.725 37.152 12.572 1.00 10.66 ? 61 TRP B CD1 1 ATOM 5223 C CD2 . TRP B 1 61 ? 23.681 36.092 14.288 1.00 9.04 ? 61 TRP B CD2 1 ATOM 5224 N NE1 . TRP B 1 61 ? 21.844 36.192 13.009 1.00 9.40 ? 61 TRP B NE1 1 ATOM 5225 C CE2 . TRP B 1 61 ? 22.409 35.528 14.064 1.00 8.23 ? 61 TRP B CE2 1 ATOM 5226 C CE3 . TRP B 1 61 ? 24.478 35.585 15.320 1.00 7.55 ? 61 TRP B CE3 1 ATOM 5227 C CZ2 . TRP B 1 61 ? 21.913 34.487 14.834 1.00 8.71 ? 61 TRP B CZ2 1 ATOM 5228 C CZ3 . TRP B 1 61 ? 23.991 34.552 16.084 1.00 7.60 ? 61 TRP B CZ3 1 ATOM 5229 C CH2 . TRP B 1 61 ? 22.716 34.011 15.840 1.00 9.65 ? 61 TRP B CH2 1 ATOM 5230 N N . THR B 1 62 ? 25.108 38.453 10.379 1.00 22.20 ? 62 THR B N 1 ATOM 5231 C CA . THR B 1 62 ? 24.575 38.425 9.029 1.00 24.63 ? 62 THR B CA 1 ATOM 5232 C C . THR B 1 62 ? 25.657 38.871 8.074 1.00 26.74 ? 62 THR B C 1 ATOM 5233 O O . THR B 1 62 ? 25.627 39.982 7.559 1.00 26.64 ? 62 THR B O 1 ATOM 5234 C CB . THR B 1 62 ? 23.346 39.338 8.874 1.00 24.92 ? 62 THR B CB 1 ATOM 5235 O OG1 . THR B 1 62 ? 22.272 38.815 9.663 1.00 25.97 ? 62 THR B OG1 1 ATOM 5236 C CG2 . THR B 1 62 ? 22.900 39.399 7.414 1.00 25.64 ? 62 THR B CG2 1 ATOM 5237 N N . GLN B 1 63 ? 26.626 37.984 7.877 1.00 29.35 ? 63 GLN B N 1 ATOM 5238 C CA . GLN B 1 63 ? 27.765 38.187 6.979 1.00 30.48 ? 63 GLN B CA 1 ATOM 5239 C C . GLN B 1 63 ? 27.658 39.437 6.114 1.00 29.50 ? 63 GLN B C 1 ATOM 5240 O O . GLN B 1 63 ? 28.500 40.332 6.156 1.00 27.13 ? 63 GLN B O 1 ATOM 5241 C CB . GLN B 1 63 ? 27.869 36.985 6.049 1.00 33.51 ? 63 GLN B CB 1 ATOM 5242 C CG . GLN B 1 63 ? 27.597 35.664 6.726 1.00 38.69 ? 63 GLN B CG 1 ATOM 5243 C CD . GLN B 1 63 ? 27.233 34.573 5.739 1.00 41.57 ? 63 GLN B CD 1 ATOM 5244 O OE1 . GLN B 1 63 ? 27.067 33.410 6.116 1.00 44.20 ? 63 GLN B OE1 1 ATOM 5245 N NE2 . GLN B 1 63 ? 27.100 34.942 4.465 1.00 43.09 ? 63 GLN B NE2 1 ATOM 5246 N N . ARG B 1 64 ? 26.600 39.436 5.312 1.00 29.55 ? 64 ARG B N 1 ATOM 5247 C CA . ARG B 1 64 ? 26.246 40.485 4.364 1.00 28.28 ? 64 ARG B CA 1 ATOM 5248 C C . ARG B 1 64 ? 25.952 41.899 4.959 1.00 26.41 ? 64 ARG B C 1 ATOM 5249 O O . ARG B 1 64 ? 25.208 42.708 4.385 1.00 26.04 ? 64 ARG B O 1 ATOM 5250 C CB . ARG B 1 64 ? 25.096 39.913 3.499 1.00 30.13 ? 64 ARG B CB 1 ATOM 5251 C CG . ARG B 1 64 ? 23.898 40.789 3.216 1.00 34.68 ? 64 ARG B CG 1 ATOM 5252 C CD . ARG B 1 64 ? 22.920 40.781 4.369 1.00 37.22 ? 64 ARG B CD 1 ATOM 5253 N NE . ARG B 1 64 ? 21.815 41.706 4.138 1.00 41.26 ? 64 ARG B NE 1 ATOM 5254 C CZ . ARG B 1 64 ? 20.632 41.621 4.739 1.00 42.64 ? 64 ARG B CZ 1 ATOM 5255 N NH1 . ARG B 1 64 ? 20.396 40.646 5.611 1.00 43.95 ? 64 ARG B NH1 1 ATOM 5256 N NH2 . ARG B 1 64 ? 19.681 42.509 4.471 1.00 44.01 ? 64 ARG B NH2 1 ATOM 5257 N N . LYS B 1 65 ? 26.590 42.183 6.097 1.00 22.96 ? 65 LYS B N 1 ATOM 5258 C CA . LYS B 1 65 ? 26.491 43.460 6.815 1.00 18.72 ? 65 LYS B CA 1 ATOM 5259 C C . LYS B 1 65 ? 27.893 43.717 7.380 1.00 16.23 ? 65 LYS B C 1 ATOM 5260 O O . LYS B 1 65 ? 28.617 42.767 7.684 1.00 17.49 ? 65 LYS B O 1 ATOM 5261 C CB . LYS B 1 65 ? 25.491 43.349 7.973 1.00 18.42 ? 65 LYS B CB 1 ATOM 5262 C CG . LYS B 1 65 ? 24.195 42.593 7.640 1.00 19.75 ? 65 LYS B CG 1 ATOM 5263 C CD . LYS B 1 65 ? 23.050 43.495 7.150 1.00 19.08 ? 65 LYS B CD 1 ATOM 5264 C CE . LYS B 1 65 ? 22.694 44.545 8.193 1.00 18.08 ? 65 LYS B CE 1 ATOM 5265 N NZ . LYS B 1 65 ? 21.485 45.315 7.812 1.00 16.49 ? 65 LYS B NZ 1 ATOM 5266 N N . THR B 1 66 ? 28.287 44.945 7.545 1.00 11.58 ? 66 THR B N 1 ATOM 5267 C CA . THR B 1 66 ? 29.612 45.194 8.080 1.00 7.07 ? 66 THR B CA 1 ATOM 5268 C C . THR B 1 66 ? 29.607 45.962 9.361 1.00 5.88 ? 66 THR B C 1 ATOM 5269 O O . THR B 1 66 ? 28.631 46.624 9.711 1.00 4.69 ? 66 THR B O 1 ATOM 5270 C CB . THR B 1 66 ? 30.403 46.171 7.147 1.00 6.51 ? 66 THR B CB 1 ATOM 5271 O OG1 . THR B 1 66 ? 29.597 47.315 6.895 1.00 4.28 ? 66 THR B OG1 1 ATOM 5272 C CG2 . THR B 1 66 ? 30.759 45.488 5.843 1.00 7.23 ? 66 THR B CG2 1 ATOM 5273 N N . ARG B 1 67 ? 30.741 45.852 10.056 1.00 4.96 ? 67 ARG B N 1 ATOM 5274 C CA . ARG B 1 67 ? 30.713 47.468 10.907 1.00 6.20 ? 67 ARG B CA 1 ATOM 5275 C C . ARG B 1 67 ? 31.673 48.563 10.482 1.00 6.08 ? 67 ARG B C 1 ATOM 5276 O O . ARG B 1 67 ? 32.856 48.303 10.267 1.00 5.69 ? 67 ARG B O 1 ATOM 5277 C CB . ARG B 1 67 ? 31.373 46.604 11.989 1.00 6.19 ? 67 ARG B CB 1 ATOM 5278 C CG . ARG B 1 67 ? 31.328 47.209 13.397 1.00 5.68 ? 67 ARG B CG 1 ATOM 5279 C CD . ARG B 1 67 ? 32.536 46.797 14.218 1.00 7.37 ? 67 ARG B CD 1 ATOM 5280 N NE . ARG B 1 67 ? 32.407 47.129 15.637 1.00 9.58 ? 67 ARG B NE 1 ATOM 5281 C CZ . ARG B 1 67 ? 32.171 46.235 16.593 1.00 8.63 ? 67 ARG B CZ 1 ATOM 5282 N NH1 . ARG B 1 67 ? 32.043 44.953 16.286 1.00 8.40 ? 67 ARG B NH1 1 ATOM 5283 N NH2 . ARG B 1 67 ? 32.051 46.622 17.854 1.00 8.36 ? 67 ARG B NH2 1 ATOM 5284 N N . ASN B 1 68 ? 31.168 49.781 10.342 1.00 4.94 ? 68 ASN B N 1 ATOM 5285 C CA . ASN B 1 68 ? 32.010 50.884 9.906 1.00 4.68 ? 68 ASN B CA 1 ATOM 5286 C C . ASN B 1 68 ? 32.515 50.624 8.485 1.00 4.17 ? 68 ASN B C 1 ATOM 5287 O O . ASN B 1 68 ? 33.567 51.116 8.065 1.00 2.22 ? 68 ASN B O 1 ATOM 5288 C CB . ASN B 1 68 ? 33.160 51.083 10.888 1.00 5.53 ? 68 ASN B CB 1 ATOM 5289 C CG . ASN B 1 68 ? 32.660 51.359 12.296 1.00 8.05 ? 68 ASN B CG 1 ATOM 5290 O OD1 . ASN B 1 68 ? 31.698 52.110 12.481 1.00 9.01 ? 68 ASN B OD1 1 ATOM 5291 N ND2 . ASN B 1 68 ? 33.306 50.760 13.294 1.00 9.29 ? 68 ASN B ND2 1 ATOM 5292 N N . GLY B 1 69 ? 31.728 49.838 7.755 1.00 4.05 ? 69 GLY B N 1 ATOM 5293 C CA . GLY B 1 69 ? 32.038 49.523 6.374 1.00 4.63 ? 69 GLY B CA 1 ATOM 5294 C C . GLY B 1 69 ? 33.035 48.418 6.115 1.00 4.98 ? 69 GLY B C 1 ATOM 5295 O O . GLY B 1 69 ? 33.696 48.427 5.075 1.00 5.45 ? 69 GLY B O 1 ATOM 5296 N N . PHE B 1 70 ? 33.139 47.462 7.036 1.00 5.86 ? 70 PHE B N 1 ATOM 5297 C CA . PHE B 1 70 ? 34.082 46.348 6.886 1.00 6.22 ? 70 PHE B CA 1 ATOM 5298 C C . PHE B 1 70 ? 33.556 45.023 7.420 1.00 6.52 ? 70 PHE B C 1 ATOM 5299 O O . PHE B 1 70 ? 32.644 44.998 8.241 1.00 5.95 ? 70 PHE B O 1 ATOM 5300 C CB . PHE B 1 70 ? 35.395 46.674 7.599 1.00 6.24 ? 70 PHE B CB 1 ATOM 5301 C CG . PHE B 1 70 ? 36.144 47.817 6.992 1.00 6.97 ? 70 PHE B CG 1 ATOM 5302 C CD1 . PHE B 1 70 ? 36.155 49.068 7.599 1.00 7.60 ? 70 PHE B CD1 1 ATOM 5303 C CD2 . PHE B 1 70 ? 36.828 47.644 5.793 1.00 8.18 ? 70 PHE B CD2 1 ATOM 5304 C CE1 . PHE B 1 70 ? 36.841 50.139 7.018 1.00 9.31 ? 70 PHE B CE1 1 ATOM 5305 C CE2 . PHE B 1 70 ? 37.514 48.701 5.201 1.00 9.26 ? 70 PHE B CE2 1 ATOM 5306 C CZ . PHE B 1 70 ? 37.521 49.954 5.815 1.00 9.37 ? 70 PHE B CZ 1 ATOM 5307 N N . ARG B 1 71 ? 34.136 43.921 6.955 1.00 8.58 ? 71 ARG B N 1 ATOM 5308 C CA . ARG B 1 71 ? 33.727 42.599 7.425 1.00 11.89 ? 71 ARG B CA 1 ATOM 5309 C C . ARG B 1 71 ? 34.550 42.236 8.662 1.00 11.08 ? 71 ARG B C 1 ATOM 5310 O O . ARG B 1 71 ? 35.787 42.237 8.630 1.00 11.53 ? 71 ARG B O 1 ATOM 5311 C CB . ARG B 1 71 ? 33.955 41.509 6.360 1.00 18.62 ? 71 ARG B CB 1 ATOM 5312 C CG . ARG B 1 71 ? 33.419 41.807 4.950 1.00 27.97 ? 71 ARG B CG 1 ATOM 5313 C CD . ARG B 1 71 ? 33.396 40.544 4.072 1.00 33.51 ? 71 ARG B CD 1 ATOM 5314 N NE . ARG B 1 71 ? 32.129 39.813 4.194 1.00 42.51 ? 71 ARG B NE 1 ATOM 5315 C CZ . ARG B 1 71 ? 31.941 38.537 3.848 1.00 45.44 ? 71 ARG B CZ 1 ATOM 5316 N NH1 . ARG B 1 71 ? 32.940 37.813 3.353 1.00 48.34 ? 71 ARG B NH1 1 ATOM 5317 N NH2 . ARG B 1 71 ? 30.740 37.984 3.987 1.00 48.24 ? 71 ARG B NH2 1 ATOM 5318 N N . VAL B 1 72 ? 33.863 41.937 9.757 1.00 7.99 ? 72 VAL B N 1 ATOM 5319 C CA . VAL B 1 72 ? 34.542 41.553 10.984 1.00 5.27 ? 72 VAL B CA 1 ATOM 5320 C C . VAL B 1 72 ? 35.206 40.196 10.763 1.00 4.06 ? 72 VAL B C 1 ATOM 5321 O O . VAL B 1 72 ? 34.570 39.239 10.306 1.00 2.00 ? 72 VAL B O 1 ATOM 5322 C CB . VAL B 1 72 ? 33.551 41.452 12.140 1.00 3.52 ? 72 VAL B CB 1 ATOM 5323 C CG1 . VAL B 1 72 ? 33.218 42.830 12.642 1.00 2.52 ? 72 VAL B CG1 1 ATOM 5324 C CG2 . VAL B 1 72 ? 32.283 40.759 11.663 1.00 3.49 ? 72 VAL B CG2 1 ATOM 5325 N N . PRO B 1 73 ? 36.504 40.100 11.076 1.00 2.00 ? 73 PRO B N 1 ATOM 5326 C CA . PRO B 1 73 ? 37.242 38.853 10.904 1.00 2.00 ? 73 PRO B CA 1 ATOM 5327 C C . PRO B 1 73 ? 36.669 37.731 11.757 1.00 2.00 ? 73 PRO B C 1 ATOM 5328 O O . PRO B 1 73 ? 36.199 37.962 12.871 1.00 2.00 ? 73 PRO B O 1 ATOM 5329 C CB . PRO B 1 73 ? 38.655 39.240 11.322 1.00 2.00 ? 73 PRO B CB 1 ATOM 5330 C CG . PRO B 1 73 ? 38.412 40.241 12.390 1.00 2.08 ? 73 PRO B CG 1 ATOM 5331 C CD . PRO B 1 73 ? 37.326 41.099 11.779 1.00 2.34 ? 73 PRO B CD 1 ATOM 5332 N N . LEU B 1 74 ? 36.695 36.516 11.222 1.00 2.00 ? 74 LEU B N 1 ATOM 5333 C CA . LEU B 1 74 ? 36.196 35.374 11.963 1.00 2.00 ? 74 LEU B CA 1 ATOM 5334 C C . LEU B 1 74 ? 36.921 35.333 13.292 1.00 2.00 ? 74 LEU B C 1 ATOM 5335 O O . LEU B 1 74 ? 38.077 35.738 13.387 1.00 2.00 ? 74 LEU B O 1 ATOM 5336 C CB . LEU B 1 74 ? 36.493 34.083 11.223 1.00 2.00 ? 74 LEU B CB 1 ATOM 5337 C CG . LEU B 1 74 ? 35.763 33.694 9.945 1.00 2.00 ? 74 LEU B CG 1 ATOM 5338 C CD1 . LEU B 1 74 ? 36.183 32.264 9.642 1.00 3.18 ? 74 LEU B CD1 1 ATOM 5339 C CD2 . LEU B 1 74 ? 34.243 33.761 10.095 1.00 2.00 ? 74 LEU B CD2 1 ATOM 5340 N N . ALA B 1 75 ? 36.251 34.835 14.319 1.00 2.00 ? 75 ALA B N 1 ATOM 5341 C CA . ALA B 1 75 ? 36.875 34.747 15.632 1.00 2.60 ? 75 ALA B CA 1 ATOM 5342 C C . ALA B 1 75 ? 38.154 33.899 15.595 1.00 2.00 ? 75 ALA B C 1 ATOM 5343 O O . ALA B 1 75 ? 39.227 34.364 15.974 1.00 2.00 ? 75 ALA B O 1 ATOM 5344 C CB . ALA B 1 75 ? 35.884 34.162 16.635 1.00 2.00 ? 75 ALA B CB 1 ATOM 5345 N N . ARG B 1 76 ? 38.017 32.662 15.120 1.00 2.46 ? 76 ARG B N 1 ATOM 5346 C CA . ARG B 1 76 ? 39.110 31.687 15.024 1.00 3.21 ? 76 ARG B CA 1 ATOM 5347 C C . ARG B 1 76 ? 40.344 32.137 14.227 1.00 2.41 ? 76 ARG B C 1 ATOM 5348 O O . ARG B 1 76 ? 41.451 31.644 14.463 1.00 2.00 ? 76 ARG B O 1 ATOM 5349 C CB . ARG B 1 76 ? 38.551 30.373 14.448 1.00 2.30 ? 76 ARG B CB 1 ATOM 5350 C CG . ARG B 1 76 ? 39.557 29.258 14.181 1.00 2.00 ? 76 ARG B CG 1 ATOM 5351 C CD . ARG B 1 76 ? 40.166 28.619 15.434 1.00 2.00 ? 76 ARG B CD 1 ATOM 5352 N NE . ARG B 1 76 ? 41.107 27.561 15.043 1.00 2.38 ? 76 ARG B NE 1 ATOM 5353 C CZ . ARG B 1 76 ? 41.911 26.879 15.861 1.00 2.00 ? 76 ARG B CZ 1 ATOM 5354 N NH1 . ARG B 1 76 ? 41.927 27.106 17.163 1.00 2.00 ? 76 ARG B NH1 1 ATOM 5355 N NH2 . ARG B 1 76 ? 42.724 25.966 15.363 1.00 2.00 ? 76 ARG B NH2 1 ATOM 5356 N N . GLU B 1 77 ? 40.166 33.062 13.286 1.00 2.22 ? 77 GLU B N 1 ATOM 5357 C CA . GLU B 1 77 ? 41.304 33.541 12.505 1.00 3.14 ? 77 GLU B CA 1 ATOM 5358 C C . GLU B 1 77 ? 42.140 34.501 13.346 1.00 3.98 ? 77 GLU B C 1 ATOM 5359 O O . GLU B 1 77 ? 43.374 34.440 13.336 1.00 3.88 ? 77 GLU B O 1 ATOM 5360 C CB . GLU B 1 77 ? 40.845 34.240 11.218 1.00 3.29 ? 77 GLU B CB 1 ATOM 5361 C CG . GLU B 1 77 ? 42.003 34.753 10.359 1.00 3.17 ? 77 GLU B CG 1 ATOM 5362 C CD . GLU B 1 77 ? 41.644 34.919 8.885 1.00 5.45 ? 77 GLU B CD 1 ATOM 5363 O OE1 . GLU B 1 77 ? 40.543 34.485 8.464 1.00 7.02 ? 77 GLU B OE1 1 ATOM 5364 O OE2 . GLU B 1 77 ? 42.478 35.477 8.137 1.00 4.93 ? 77 GLU B OE2 1 ATOM 5365 N N . VAL B 1 78 ? 41.464 35.386 14.076 1.00 3.38 ? 78 VAL B N 1 ATOM 5366 C CA . VAL B 1 78 ? 42.148 36.342 14.936 1.00 3.18 ? 78 VAL B CA 1 ATOM 5367 C C . VAL B 1 78 ? 43.084 35.557 15.859 1.00 2.35 ? 78 VAL B C 1 ATOM 5368 O O . VAL B 1 78 ? 44.226 35.953 16.099 1.00 2.59 ? 78 VAL B O 1 ATOM 5369 C CB . VAL B 1 78 ? 41.130 37.144 15.767 1.00 2.16 ? 78 VAL B CB 1 ATOM 5370 C CG1 . VAL B 1 78 ? 41.848 38.106 16.701 1.00 2.00 ? 78 VAL B CG1 1 ATOM 5371 C CG2 . VAL B 1 78 ? 40.198 37.896 14.829 1.00 2.00 ? 78 VAL B CG2 1 ATOM 5372 N N . SER B 1 79 ? 42.590 34.424 16.345 1.00 2.04 ? 79 SER B N 1 ATOM 5373 C CA . SER B 1 79 ? 43.350 33.550 17.228 1.00 2.63 ? 79 SER B CA 1 ATOM 5374 C C . SER B 1 79 ? 44.623 33.020 16.561 1.00 2.45 ? 79 SER B C 1 ATOM 5375 O O . SER B 1 79 ? 45.723 33.197 17.092 1.00 2.52 ? 79 SER B O 1 ATOM 5376 C CB . SER B 1 79 ? 42.464 32.374 17.669 1.00 3.02 ? 79 SER B CB 1 ATOM 5377 O OG . SER B 1 79 ? 43.128 31.514 18.580 1.00 2.00 ? 79 SER B OG 1 ATOM 5378 N N . ASN B 1 80 ? 44.466 32.379 15.401 1.00 2.30 ? 80 ASN B N 1 ATOM 5379 C CA . ASN B 1 80 ? 45.595 31.797 14.664 1.00 3.07 ? 80 ASN B CA 1 ATOM 5380 C C . ASN B 1 80 ? 46.610 32.807 14.137 1.00 2.43 ? 80 ASN B C 1 ATOM 5381 O O . ASN B 1 80 ? 47.814 32.693 14.373 1.00 2.00 ? 80 ASN B O 1 ATOM 5382 C CB . ASN B 1 80 ? 45.105 30.981 13.461 1.00 2.79 ? 80 ASN B CB 1 ATOM 5383 C CG . ASN B 1 80 ? 44.048 29.969 13.823 1.00 2.29 ? 80 ASN B CG 1 ATOM 5384 O OD1 . ASN B 1 80 ? 43.967 29.514 14.962 1.00 3.33 ? 80 ASN B OD1 1 ATOM 5385 N ND2 . ASN B 1 80 ? 43.237 29.592 12.840 1.00 2.01 ? 80 ASN B ND2 1 ATOM 5386 N N . LYS B 1 81 ? 46.116 33.783 13.393 1.00 2.60 ? 81 LYS B N 1 ATOM 5387 C CA . LYS B 1 81 ? 46.986 34.778 12.808 1.00 4.25 ? 81 LYS B CA 1 ATOM 5388 C C . LYS B 1 81 ? 47.711 35.608 13.846 1.00 5.14 ? 81 LYS B C 1 ATOM 5389 O O . LYS B 1 81 ? 48.831 36.056 13.602 1.00 6.79 ? 81 LYS B O 1 ATOM 5390 C CB . LYS B 1 81 ? 46.179 35.702 11.896 1.00 5.76 ? 81 LYS B CB 1 ATOM 5391 C CG . LYS B 1 81 ? 45.565 35.021 10.689 1.00 7.61 ? 81 LYS B CG 1 ATOM 5392 C CD . LYS B 1 81 ? 46.532 35.014 9.525 1.00 11.23 ? 81 LYS B CD 1 ATOM 5393 C CE . LYS B 1 81 ? 46.015 34.168 8.359 1.00 13.72 ? 81 LYS B CE 1 ATOM 5394 N NZ . LYS B 1 81 ? 44.737 34.685 7.789 1.00 13.83 ? 81 LYS B NZ 1 ATOM 5395 N N . ILE B 1 82 ? 47.099 35.798 15.012 1.00 4.61 ? 82 ILE B N 1 ATOM 5396 C CA . ILE B 1 82 ? 47.719 36.649 16.028 1.00 4.50 ? 82 ILE B CA 1 ATOM 5397 C C . ILE B 1 82 ? 47.915 36.145 17.453 1.00 2.13 ? 82 ILE B C 1 ATOM 5398 O O . ILE B 1 82 ? 48.892 36.518 18.095 1.00 2.00 ? 82 ILE B O 1 ATOM 5399 C CB . ILE B 1 82 ? 46.966 37.996 16.101 1.00 2.49 ? 82 ILE B CB 1 ATOM 5400 C CG1 . ILE B 1 82 ? 46.997 38.657 14.719 1.00 2.00 ? 82 ILE B CG1 1 ATOM 5401 C CG2 . ILE B 1 82 ? 47.592 38.894 17.154 1.00 2.00 ? 82 ILE B CG2 1 ATOM 5402 C CD1 . ILE B 1 82 ? 46.159 39.885 14.598 1.00 2.74 ? 82 ILE B CD1 1 ATOM 5403 N N . VAL B 1 83 ? 47.015 35.297 17.941 1.00 2.00 ? 83 VAL B N 1 ATOM 5404 C CA . VAL B 1 83 ? 47.097 34.807 19.315 1.00 2.00 ? 83 VAL B CA 1 ATOM 5405 C C . VAL B 1 83 ? 48.040 33.634 19.638 1.00 2.57 ? 83 VAL B C 1 ATOM 5406 O O . VAL B 1 83 ? 48.711 33.644 20.677 1.00 2.00 ? 83 VAL B O 1 ATOM 5407 C CB . VAL B 1 83 ? 45.679 34.470 19.833 1.00 2.00 ? 83 VAL B CB 1 ATOM 5408 C CG1 . VAL B 1 83 ? 45.726 34.054 21.301 1.00 2.00 ? 83 VAL B CG1 1 ATOM 5409 C CG2 . VAL B 1 83 ? 44.782 35.676 19.666 1.00 2.00 ? 83 VAL B CG2 1 ATOM 5410 N N . GLY B 1 84 ? 48.099 32.638 18.762 1.00 2.00 ? 84 GLY B N 1 ATOM 5411 C CA . GLY B 1 84 ? 48.945 31.481 19.015 1.00 2.00 ? 84 GLY B CA 1 ATOM 5412 C C . GLY B 1 84 ? 50.455 31.656 18.952 1.00 2.00 ? 84 GLY B C 1 ATOM 5413 O O . GLY B 1 84 ? 50.957 32.688 18.508 1.00 2.00 ? 84 GLY B O 1 ATOM 5414 N N . TYR B 1 85 ? 51.166 30.622 19.413 1.00 3.30 ? 85 TYR B N 1 ATOM 5415 C CA . TYR B 1 85 ? 52.635 30.561 19.437 1.00 2.00 ? 85 TYR B CA 1 ATOM 5416 C C . TYR B 1 85 ? 53.071 29.121 19.736 1.00 2.00 ? 85 TYR B C 1 ATOM 5417 O O . TYR B 1 85 ? 52.467 28.450 20.573 1.00 2.00 ? 85 TYR B O 1 ATOM 5418 C CB . TYR B 1 85 ? 53.194 31.515 20.498 1.00 2.77 ? 85 TYR B CB 1 ATOM 5419 C CG . TYR B 1 85 ? 52.988 31.076 21.931 1.00 3.09 ? 85 TYR B CG 1 ATOM 5420 C CD1 . TYR B 1 85 ? 53.857 30.164 22.533 1.00 3.67 ? 85 TYR B CD1 1 ATOM 5421 C CD2 . TYR B 1 85 ? 51.929 31.578 22.693 1.00 2.37 ? 85 TYR B CD2 1 ATOM 5422 C CE1 . TYR B 1 85 ? 53.677 29.764 23.862 1.00 3.81 ? 85 TYR B CE1 1 ATOM 5423 C CE2 . TYR B 1 85 ? 51.738 31.185 24.021 1.00 2.02 ? 85 TYR B CE2 1 ATOM 5424 C CZ . TYR B 1 85 ? 52.616 30.277 24.599 1.00 2.79 ? 85 TYR B CZ 1 ATOM 5425 O OH . TYR B 1 85 ? 52.445 29.874 25.904 1.00 2.00 ? 85 TYR B OH 1 ATOM 5426 N N . LEU B 1 86 ? 54.126 28.654 19.070 1.00 3.50 ? 86 LEU B N 1 ATOM 5427 C CA . LEU B 1 86 ? 54.601 27.273 19.236 1.00 3.45 ? 86 LEU B CA 1 ATOM 5428 C C . LEU B 1 86 ? 55.638 26.963 20.303 1.00 2.00 ? 86 LEU B C 1 ATOM 5429 O O . LEU B 1 86 ? 55.505 25.982 21.013 1.00 2.00 ? 86 LEU B O 1 ATOM 5430 C CB . LEU B 1 86 ? 55.139 26.733 17.896 1.00 3.20 ? 86 LEU B CB 1 ATOM 5431 C CG . LEU B 1 86 ? 54.198 25.958 16.962 1.00 3.70 ? 86 LEU B CG 1 ATOM 5432 C CD1 . LEU B 1 86 ? 54.799 25.828 15.567 1.00 3.38 ? 86 LEU B CD1 1 ATOM 5433 C CD2 . LEU B 1 86 ? 53.939 24.591 17.550 1.00 4.07 ? 86 LEU B CD2 1 ATOM 5434 N N . ASP B 1 87 ? 56.667 27.787 20.417 1.00 2.00 ? 87 ASP B N 1 ATOM 5435 C CA . ASP B 1 87 ? 57.751 27.527 21.359 1.00 2.29 ? 87 ASP B CA 1 ATOM 5436 C C . ASP B 1 87 ? 57.599 28.078 22.778 1.00 3.87 ? 87 ASP B C 1 ATOM 5437 O O . ASP B 1 87 ? 57.683 29.286 22.979 1.00 4.82 ? 87 ASP B O 1 ATOM 5438 C CB . ASP B 1 87 ? 59.048 28.047 20.742 1.00 3.32 ? 87 ASP B CB 1 ATOM 5439 C CG . ASP B 1 87 ? 60.239 27.839 21.634 1.00 5.70 ? 87 ASP B CG 1 ATOM 5440 O OD1 . ASP B 1 87 ? 60.275 26.798 22.323 1.00 7.86 ? 87 ASP B OD1 1 ATOM 5441 O OD2 . ASP B 1 87 ? 61.144 28.705 21.637 1.00 6.18 ? 87 ASP B OD2 1 ATOM 5442 N N . GLU B 1 88 ? 57.411 27.200 23.767 1.00 3.06 ? 88 GLU B N 1 ATOM 5443 C CA . GLU B 1 88 ? 57.250 27.643 25.163 1.00 2.00 ? 88 GLU B CA 1 ATOM 5444 C C . GLU B 1 88 ? 58.559 28.095 25.813 1.00 2.82 ? 88 GLU B C 1 ATOM 5445 O O . GLU B 1 88 ? 58.573 28.523 26.970 1.00 2.00 ? 88 GLU B O 1 ATOM 5446 C CB . GLU B 1 88 ? 56.664 26.525 26.033 1.00 2.00 ? 88 GLU B CB 1 ATOM 5447 C CG . GLU B 1 88 ? 55.240 26.097 25.728 1.00 4.95 ? 88 GLU B CG 1 ATOM 5448 C CD . GLU B 1 88 ? 54.204 27.165 26.036 1.00 6.36 ? 88 GLU B CD 1 ATOM 5449 O OE1 . GLU B 1 88 ? 54.365 27.898 27.039 1.00 6.80 ? 88 GLU B OE1 1 ATOM 5450 O OE2 . GLU B 1 88 ? 53.212 27.251 25.281 1.00 7.79 ? 88 GLU B OE2 1 ATOM 5451 N N . GLU B 1 89 ? 59.662 27.994 25.082 1.00 4.57 ? 89 GLU B N 1 ATOM 5452 C CA . GLU B 1 89 ? 60.941 28.371 25.645 1.00 5.61 ? 89 GLU B CA 1 ATOM 5453 C C . GLU B 1 89 ? 60.958 29.734 26.292 1.00 4.22 ? 89 GLU B C 1 ATOM 5454 O O . GLU B 1 89 ? 60.599 30.733 25.678 1.00 3.29 ? 89 GLU B O 1 ATOM 5455 C CB . GLU B 1 89 ? 62.034 28.320 24.593 1.00 12.41 ? 89 GLU B CB 1 ATOM 5456 C CG . GLU B 1 89 ? 63.347 28.929 25.074 1.00 22.69 ? 89 GLU B CG 1 ATOM 5457 C CD . GLU B 1 89 ? 64.470 28.785 24.056 1.00 26.65 ? 89 GLU B CD 1 ATOM 5458 O OE1 . GLU B 1 89 ? 65.020 27.664 23.912 1.00 29.82 ? 89 GLU B OE1 1 ATOM 5459 O OE2 . GLU B 1 89 ? 64.795 29.791 23.385 1.00 29.63 ? 89 GLU B OE2 1 ATOM 5460 N N . GLY B 1 90 ? 61.399 29.747 27.545 1.00 5.28 ? 90 GLY B N 1 ATOM 5461 C CA . GLY B 1 90 ? 61.514 30.973 28.318 1.00 5.45 ? 90 GLY B CA 1 ATOM 5462 C C . GLY B 1 90 ? 60.406 31.976 28.098 1.00 4.99 ? 90 GLY B C 1 ATOM 5463 O O . GLY B 1 90 ? 60.649 33.149 27.796 1.00 5.79 ? 90 GLY B O 1 ATOM 5464 N N . VAL B 1 91 ? 59.180 31.507 28.262 1.00 3.84 ? 91 VAL B N 1 ATOM 5465 C CA . VAL B 1 91 ? 58.019 32.348 28.087 1.00 2.13 ? 91 VAL B CA 1 ATOM 5466 C C . VAL B 1 91 ? 57.362 32.553 29.441 1.00 2.00 ? 91 VAL B C 1 ATOM 5467 O O . VAL B 1 91 ? 56.150 32.719 29.521 1.00 2.90 ? 91 VAL B O 1 ATOM 5468 C CB . VAL B 1 91 ? 57.013 31.659 27.197 1.00 2.00 ? 91 VAL B CB 1 ATOM 5469 C CG1 . VAL B 1 91 ? 56.480 30.426 27.916 1.00 2.69 ? 91 VAL B CG1 1 ATOM 5470 C CG2 . VAL B 1 91 ? 55.890 32.607 26.848 1.00 2.75 ? 91 VAL B CG2 1 ATOM 5471 N N . LEU B 1 92 ? 58.148 32.547 30.511 1.00 2.00 ? 92 LEU B N 1 ATOM 5472 C CA . LEU B 1 92 ? 57.561 32.680 31.842 1.00 2.74 ? 92 LEU B CA 1 ATOM 5473 C C . LEU B 1 92 ? 57.892 33.941 32.615 1.00 3.56 ? 92 LEU B C 1 ATOM 5474 O O . LEU B 1 92 ? 59.050 34.363 32.688 1.00 2.47 ? 92 LEU B O 1 ATOM 5475 C CB . LEU B 1 92 ? 57.925 31.464 32.706 1.00 2.01 ? 92 LEU B CB 1 ATOM 5476 C CG . LEU B 1 92 ? 57.255 30.108 32.449 1.00 2.00 ? 92 LEU B CG 1 ATOM 5477 C CD1 . LEU B 1 92 ? 57.384 29.707 30.995 1.00 2.00 ? 92 LEU B CD1 1 ATOM 5478 C CD2 . LEU B 1 92 ? 57.904 29.060 33.334 1.00 2.00 ? 92 LEU B CD2 1 ATOM 5479 N N . ASP B 1 93 ? 56.847 34.534 33.193 1.00 4.85 ? 93 ASP B N 1 ATOM 5480 C CA . ASP B 1 93 ? 56.968 35.743 34.002 1.00 5.16 ? 93 ASP B CA 1 ATOM 5481 C C . ASP B 1 93 ? 57.986 35.310 35.023 1.00 5.43 ? 93 ASP B C 1 ATOM 5482 O O . ASP B 1 93 ? 57.931 34.178 35.490 1.00 6.94 ? 93 ASP B O 1 ATOM 5483 C CB . ASP B 1 93 ? 55.636 36.059 34.686 1.00 6.64 ? 93 ASP B CB 1 ATOM 5484 C CG . ASP B 1 93 ? 55.634 37.414 35.378 1.00 7.95 ? 93 ASP B CG 1 ATOM 5485 O OD1 . ASP B 1 93 ? 56.601 37.694 36.126 1.00 7.12 ? 93 ASP B OD1 1 ATOM 5486 O OD2 . ASP B 1 93 ? 54.658 38.185 35.181 1.00 5.16 ? 93 ASP B OD2 1 ATOM 5487 N N . GLN B 1 94 ? 58.907 36.188 35.385 1.00 5.11 ? 94 GLN B N 1 ATOM 5488 C CA . GLN B 1 94 ? 59.936 35.772 36.314 1.00 5.12 ? 94 GLN B CA 1 ATOM 5489 C C . GLN B 1 94 ? 59.923 36.349 37.710 1.00 4.78 ? 94 GLN B C 1 ATOM 5490 O O . GLN B 1 94 ? 60.832 36.085 38.492 1.00 4.15 ? 94 GLN B O 1 ATOM 5491 C CB . GLN B 1 94 ? 61.290 36.011 35.689 1.00 7.64 ? 94 GLN B CB 1 ATOM 5492 C CG . GLN B 1 94 ? 62.303 35.010 36.121 1.00 13.35 ? 94 GLN B CG 1 ATOM 5493 C CD . GLN B 1 94 ? 63.216 34.665 34.984 1.00 16.89 ? 94 GLN B CD 1 ATOM 5494 O OE1 . GLN B 1 94 ? 63.797 35.561 34.355 1.00 19.79 ? 94 GLN B OE1 1 ATOM 5495 N NE2 . GLN B 1 94 ? 63.350 33.366 34.694 1.00 18.16 ? 94 GLN B NE2 1 ATOM 5496 N N . ASN B 1 95 ? 58.914 37.150 38.017 1.00 5.84 ? 95 ASN B N 1 ATOM 5497 C CA . ASN B 1 95 ? 58.787 37.713 39.351 1.00 5.43 ? 95 ASN B CA 1 ATOM 5498 C C . ASN B 1 95 ? 57.312 37.575 39.695 1.00 4.41 ? 95 ASN B C 1 ATOM 5499 O O . ASN B 1 95 ? 56.685 38.514 40.167 1.00 3.21 ? 95 ASN B O 1 ATOM 5500 C CB . ASN B 1 95 ? 59.236 39.184 39.386 1.00 10.02 ? 95 ASN B CB 1 ATOM 5501 C CG . ASN B 1 95 ? 59.391 39.700 40.805 1.00 17.52 ? 95 ASN B CG 1 ATOM 5502 O OD1 . ASN B 1 95 ? 59.632 38.907 41.714 1.00 14.75 ? 95 ASN B OD1 1 ATOM 5503 N ND2 . ASN B 1 95 ? 59.267 41.014 41.005 1.00 28.64 ? 95 ASN B ND2 1 ATOM 5504 N N . ARG B 1 96 ? 56.773 36.383 39.432 1.00 4.88 ? 96 ARG B N 1 ATOM 5505 C CA . ARG B 1 96 ? 55.365 36.051 39.679 1.00 4.46 ? 96 ARG B CA 1 ATOM 5506 C C . ARG B 1 96 ? 55.129 34.536 39.874 1.00 6.18 ? 96 ARG B C 1 ATOM 5507 O O . ARG B 1 96 ? 55.320 33.738 38.950 1.00 7.03 ? 96 ARG B O 1 ATOM 5508 C CB . ARG B 1 96 ? 54.511 36.542 38.506 1.00 2.18 ? 96 ARG B CB 1 ATOM 5509 C CG . ARG B 1 96 ? 54.510 38.043 38.308 1.00 2.00 ? 96 ARG B CG 1 ATOM 5510 C CD . ARG B 1 96 ? 53.942 38.718 39.535 1.00 2.65 ? 96 ARG B CD 1 ATOM 5511 N NE . ARG B 1 96 ? 53.561 40.114 39.324 1.00 3.42 ? 96 ARG B NE 1 ATOM 5512 C CZ . ARG B 1 96 ? 54.370 41.162 39.456 1.00 2.64 ? 96 ARG B CZ 1 ATOM 5513 N NH1 . ARG B 1 96 ? 55.641 41.001 39.800 1.00 2.00 ? 96 ARG B NH1 1 ATOM 5514 N NH2 . ARG B 1 96 ? 53.892 42.384 39.258 1.00 3.40 ? 96 ARG B NH2 1 ATOM 5515 N N . SER B 1 97 ? 54.707 34.142 41.071 1.00 3.70 ? 97 SER B N 1 ATOM 5516 C CA . SER B 1 97 ? 54.442 32.736 41.350 1.00 2.84 ? 97 SER B CA 1 ATOM 5517 C C . SER B 1 97 ? 53.240 32.310 40.539 1.00 2.00 ? 97 SER B C 1 ATOM 5518 O O . SER B 1 97 ? 52.535 33.151 40.000 1.00 2.00 ? 97 SER B O 1 ATOM 5519 C CB . SER B 1 97 ? 54.119 32.538 42.830 1.00 3.87 ? 97 SER B CB 1 ATOM 5520 O OG . SER B 1 97 ? 52.892 33.172 43.168 1.00 2.90 ? 97 SER B OG 1 ATOM 5521 N N . LEU B 1 98 ? 53.005 31.005 40.463 1.00 2.00 ? 98 LEU B N 1 ATOM 5522 C CA . LEU B 1 98 ? 51.857 30.478 39.740 1.00 2.00 ? 98 LEU B CA 1 ATOM 5523 C C . LEU B 1 98 ? 50.650 30.945 40.522 1.00 2.00 ? 98 LEU B C 1 ATOM 5524 O O . LEU B 1 98 ? 49.568 31.083 39.982 1.00 2.00 ? 98 LEU B O 1 ATOM 5525 C CB . LEU B 1 98 ? 51.872 28.949 39.715 1.00 2.00 ? 98 LEU B CB 1 ATOM 5526 C CG . LEU B 1 98 ? 51.171 28.209 38.566 1.00 2.00 ? 98 LEU B CG 1 ATOM 5527 C CD1 . LEU B 1 98 ? 50.356 27.077 39.142 1.00 2.00 ? 98 LEU B CD1 1 ATOM 5528 C CD2 . LEU B 1 98 ? 50.280 29.140 37.767 1.00 2.00 ? 98 LEU B CD2 1 ATOM 5529 N N . LEU B 1 99 ? 50.846 31.186 41.809 1.00 2.00 ? 99 LEU B N 1 ATOM 5530 C CA . LEU B 1 99 ? 49.771 31.663 42.668 1.00 2.00 ? 99 LEU B CA 1 ATOM 5531 C C . LEU B 1 99 ? 49.186 32.980 42.160 1.00 2.29 ? 99 LEU B C 1 ATOM 5532 O O . LEU B 1 99 ? 48.013 33.270 42.382 1.00 2.00 ? 99 LEU B O 1 ATOM 5533 C CB . LEU B 1 99 ? 50.300 31.870 44.074 1.00 2.00 ? 99 LEU B CB 1 ATOM 5534 C CG . LEU B 1 99 ? 49.296 32.454 45.051 1.00 2.00 ? 99 LEU B CG 1 ATOM 5535 C CD1 . LEU B 1 99 ? 48.005 31.678 44.996 1.00 2.00 ? 99 LEU B CD1 1 ATOM 5536 C CD2 . LEU B 1 99 ? 49.886 32.403 46.436 1.00 2.83 ? 99 LEU B CD2 1 ATOM 5537 N N . PHE B 1 100 ? 50.033 33.757 41.482 1.00 2.65 ? 100 PHE B N 1 ATOM 5538 C CA . PHE B 1 100 ? 49.697 35.056 40.906 1.00 2.00 ? 100 PHE B CA 1 ATOM 5539 C C . PHE B 1 100 ? 48.567 34.997 39.894 1.00 3.01 ? 100 PHE B C 1 ATOM 5540 O O . PHE B 1 100 ? 47.867 35.988 39.690 1.00 5.33 ? 100 PHE B O 1 ATOM 5541 C CB . PHE B 1 100 ? 50.942 35.671 40.248 1.00 2.00 ? 100 PHE B CB 1 ATOM 5542 C CG . PHE B 1 100 ? 50.686 36.977 39.525 1.00 2.00 ? 100 PHE B CG 1 ATOM 5543 C CD1 . PHE B 1 100 ? 50.046 38.040 40.162 1.00 2.00 ? 100 PHE B CD1 1 ATOM 5544 C CD2 . PHE B 1 100 ? 51.098 37.148 38.202 1.00 2.33 ? 100 PHE B CD2 1 ATOM 5545 C CE1 . PHE B 1 100 ? 49.819 39.251 39.489 1.00 2.00 ? 100 PHE B CE1 1 ATOM 5546 C CE2 . PHE B 1 100 ? 50.874 38.357 37.526 1.00 2.00 ? 100 PHE B CE2 1 ATOM 5547 C CZ . PHE B 1 100 ? 50.237 39.404 38.170 1.00 2.00 ? 100 PHE B CZ 1 ATOM 5548 N N . MET B 1 101 ? 48.401 33.866 39.217 1.00 2.83 ? 101 MET B N 1 ATOM 5549 C CA . MET B 1 101 ? 47.299 33.788 38.280 1.00 2.00 ? 101 MET B CA 1 ATOM 5550 C C . MET B 1 101 ? 46.187 32.960 38.875 1.00 2.37 ? 101 MET B C 1 ATOM 5551 O O . MET B 1 101 ? 45.067 33.034 38.399 1.00 5.88 ? 101 MET B O 1 ATOM 5552 C CB . MET B 1 101 ? 47.718 33.240 36.902 1.00 2.00 ? 101 MET B CB 1 ATOM 5553 C CG . MET B 1 101 ? 48.108 31.773 36.792 1.00 2.00 ? 101 MET B CG 1 ATOM 5554 S SD . MET B 1 101 ? 46.702 30.643 36.869 1.00 2.05 ? 101 MET B SD 1 ATOM 5555 C CE . MET B 1 101 ? 45.586 31.450 35.820 1.00 2.00 ? 101 MET B CE 1 ATOM 5556 N N . GLN B 1 102 ? 46.457 32.191 39.926 1.00 2.00 ? 102 GLN B N 1 ATOM 5557 C CA . GLN B 1 102 ? 45.376 31.413 40.501 1.00 2.00 ? 102 GLN B CA 1 ATOM 5558 C C . GLN B 1 102 ? 44.491 32.312 41.352 1.00 2.32 ? 102 GLN B C 1 ATOM 5559 O O . GLN B 1 102 ? 43.264 32.182 41.330 1.00 2.98 ? 102 GLN B O 1 ATOM 5560 C CB . GLN B 1 102 ? 45.891 30.248 41.335 1.00 2.00 ? 102 GLN B CB 1 ATOM 5561 C CG . GLN B 1 102 ? 44.869 29.144 41.407 1.00 2.00 ? 102 GLN B CG 1 ATOM 5562 C CD . GLN B 1 102 ? 44.202 28.907 40.062 1.00 2.00 ? 102 GLN B CD 1 ATOM 5563 O OE1 . GLN B 1 102 ? 44.730 28.222 39.196 1.00 3.23 ? 102 GLN B OE1 1 ATOM 5564 N NE2 . GLN B 1 102 ? 43.034 29.500 39.869 1.00 2.00 ? 102 GLN B NE2 1 ATOM 5565 N N . TRP B 1 103 ? 45.097 33.240 42.088 1.00 2.00 ? 103 TRP B N 1 ATOM 5566 C CA . TRP B 1 103 ? 44.307 34.144 42.912 1.00 3.42 ? 103 TRP B CA 1 ATOM 5567 C C . TRP B 1 103 ? 43.514 35.066 42.004 1.00 3.51 ? 103 TRP B C 1 ATOM 5568 O O . TRP B 1 103 ? 42.503 35.647 42.403 1.00 4.39 ? 103 TRP B O 1 ATOM 5569 C CB . TRP B 1 103 ? 45.191 34.991 43.837 1.00 2.65 ? 103 TRP B CB 1 ATOM 5570 C CG . TRP B 1 103 ? 44.367 35.794 44.753 1.00 2.00 ? 103 TRP B CG 1 ATOM 5571 C CD1 . TRP B 1 103 ? 44.083 37.117 44.660 1.00 2.00 ? 103 TRP B CD1 1 ATOM 5572 C CD2 . TRP B 1 103 ? 43.608 35.294 45.842 1.00 2.00 ? 103 TRP B CD2 1 ATOM 5573 N NE1 . TRP B 1 103 ? 43.184 37.477 45.626 1.00 2.00 ? 103 TRP B NE1 1 ATOM 5574 C CE2 . TRP B 1 103 ? 42.875 36.370 46.369 1.00 2.00 ? 103 TRP B CE2 1 ATOM 5575 C CE3 . TRP B 1 103 ? 43.474 34.031 46.426 1.00 2.00 ? 103 TRP B CE3 1 ATOM 5576 C CZ2 . TRP B 1 103 ? 42.017 36.224 47.456 1.00 2.00 ? 103 TRP B CZ2 1 ATOM 5577 C CZ3 . TRP B 1 103 ? 42.625 33.884 47.503 1.00 2.08 ? 103 TRP B CZ3 1 ATOM 5578 C CH2 . TRP B 1 103 ? 41.906 34.974 48.010 1.00 2.08 ? 103 TRP B CH2 1 ATOM 5579 N N . GLY B 1 104 ? 43.988 35.213 40.779 1.00 2.00 ? 104 GLY B N 1 ATOM 5580 C CA . GLY B 1 104 ? 43.286 36.078 39.865 1.00 2.00 ? 104 GLY B CA 1 ATOM 5581 C C . GLY B 1 104 ? 41.960 35.442 39.542 1.00 2.00 ? 104 GLY B C 1 ATOM 5582 O O . GLY B 1 104 ? 40.904 35.972 39.868 1.00 2.11 ? 104 GLY B O 1 ATOM 5583 N N . GLN B 1 105 ? 42.025 34.276 38.916 1.00 2.00 ? 105 GLN B N 1 ATOM 5584 C CA . GLN B 1 105 ? 40.834 33.546 38.518 1.00 2.01 ? 105 GLN B CA 1 ATOM 5585 C C . GLN B 1 105 ? 39.811 33.401 39.626 1.00 2.00 ? 105 GLN B C 1 ATOM 5586 O O . GLN B 1 105 ? 38.634 33.169 39.360 1.00 2.00 ? 105 GLN B O 1 ATOM 5587 C CB . GLN B 1 105 ? 41.205 32.155 38.019 1.00 3.00 ? 105 GLN B CB 1 ATOM 5588 C CG . GLN B 1 105 ? 40.000 31.394 37.532 1.00 3.74 ? 105 GLN B CG 1 ATOM 5589 C CD . GLN B 1 105 ? 40.344 30.022 37.050 1.00 4.20 ? 105 GLN B CD 1 ATOM 5590 O OE1 . GLN B 1 105 ? 40.948 29.226 37.770 1.00 6.25 ? 105 GLN B OE1 1 ATOM 5591 N NE2 . GLN B 1 105 ? 39.957 29.713 35.820 1.00 3.42 ? 105 GLN B NE2 1 ATOM 5592 N N . ILE B 1 106 ? 40.272 33.517 40.866 1.00 2.15 ? 106 ILE B N 1 ATOM 5593 C CA . ILE B 1 106 ? 39.406 33.402 42.035 1.00 2.00 ? 106 ILE B CA 1 ATOM 5594 C C . ILE B 1 106 ? 38.637 34.693 42.351 1.00 2.62 ? 106 ILE B C 1 ATOM 5595 O O . ILE B 1 106 ? 37.408 34.671 42.505 1.00 2.13 ? 106 ILE B O 1 ATOM 5596 C CB . ILE B 1 106 ? 40.220 32.976 43.278 1.00 2.00 ? 106 ILE B CB 1 ATOM 5597 C CG1 . ILE B 1 106 ? 40.470 31.465 43.245 1.00 2.00 ? 106 ILE B CG1 1 ATOM 5598 C CG2 . ILE B 1 106 ? 39.507 33.411 44.540 1.00 2.00 ? 106 ILE B CG2 1 ATOM 5599 C CD1 . ILE B 1 106 ? 41.315 30.953 44.396 1.00 2.00 ? 106 ILE B CD1 1 ATOM 5600 N N . VAL B 1 107 ? 39.351 35.811 42.457 1.00 2.00 ? 107 VAL B N 1 ATOM 5601 C CA . VAL B 1 107 ? 38.691 37.099 42.651 1.00 2.00 ? 107 VAL B CA 1 ATOM 5602 C C . VAL B 1 107 ? 37.684 37.388 41.493 1.00 2.00 ? 107 VAL B C 1 ATOM 5603 O O . VAL B 1 107 ? 36.591 37.913 41.723 1.00 3.50 ? 107 VAL B O 1 ATOM 5604 C CB . VAL B 1 107 ? 39.775 38.212 42.711 1.00 2.00 ? 107 VAL B CB 1 ATOM 5605 C CG1 . VAL B 1 107 ? 39.118 39.578 42.807 1.00 2.00 ? 107 VAL B CG1 1 ATOM 5606 C CG2 . VAL B 1 107 ? 40.717 37.995 43.891 1.00 2.41 ? 107 VAL B CG2 1 ATOM 5607 N N . ASP B 1 108 ? 38.075 37.039 40.189 1.00 2.00 ? 108 ASP B N 1 ATOM 5608 C CA . ASP B 1 108 ? 37.227 37.203 38.927 1.00 2.00 ? 108 ASP B CA 1 ATOM 5609 C C . ASP B 1 108 ? 35.920 36.508 39.240 1.00 2.00 ? 108 ASP B C 1 ATOM 5610 O O . ASP B 1 108 ? 34.841 37.054 39.079 1.00 2.00 ? 108 ASP B O 1 ATOM 5611 C CB . ASP B 1 108 ? 37.777 36.516 37.607 1.00 2.81 ? 108 ASP B CB 1 ATOM 5612 C CG . ASP B 1 108 ? 36.871 36.474 36.334 1.00 2.17 ? 108 ASP B CG 1 ATOM 5613 O OD1 . ASP B 1 108 ? 35.885 35.704 36.316 1.00 2.00 ? 108 ASP B OD1 1 ATOM 5614 O OD2 . ASP B 1 108 ? 37.170 37.213 35.374 1.00 3.97 ? 108 ASP B OD2 1 ATOM 5615 N N . HIS B 1 109 ? 36.085 35.229 39.686 1.00 3.73 ? 109 HIS B N 1 ATOM 5616 C CA . HIS B 1 109 ? 34.968 34.323 40.010 1.00 3.49 ? 109 HIS B CA 1 ATOM 5617 C C . HIS B 1 109 ? 34.074 34.773 41.141 1.00 2.79 ? 109 HIS B C 1 ATOM 5618 O O . HIS B 1 109 ? 32.893 34.421 41.187 1.00 2.29 ? 109 HIS B O 1 ATOM 5619 C CB . HIS B 1 109 ? 35.473 32.932 40.301 1.00 4.15 ? 109 HIS B CB 1 ATOM 5620 C CG . HIS B 1 109 ? 35.809 32.142 39.023 1.00 3.43 ? 109 HIS B CG 1 ATOM 5621 N ND1 . HIS B 1 109 ? 35.850 30.767 38.984 1.00 4.35 ? 109 HIS B ND1 1 ATOM 5622 C CD2 . HIS B 1 109 ? 36.133 32.561 37.776 1.00 3.58 ? 109 HIS B CD2 1 ATOM 5623 C CE1 . HIS B 1 109 ? 36.184 30.369 37.771 1.00 3.82 ? 109 HIS B CE1 1 ATOM 5624 N NE2 . HIS B 1 109 ? 36.362 31.440 37.017 1.00 2.35 ? 109 HIS B NE2 1 ATOM 5625 N N . ASP B 1 110 ? 34.631 35.538 42.068 1.00 2.00 ? 110 ASP B N 1 ATOM 5626 C CA . ASP B 1 110 ? 33.806 36.041 43.142 1.00 2.57 ? 110 ASP B CA 1 ATOM 5627 C C . ASP B 1 110 ? 32.991 37.212 42.599 1.00 2.00 ? 110 ASP B C 1 ATOM 5628 O O . ASP B 1 110 ? 31.886 37.488 43.082 1.00 2.00 ? 110 ASP B O 1 ATOM 5629 C CB . ASP B 1 110 ? 34.660 36.496 44.318 1.00 4.61 ? 110 ASP B CB 1 ATOM 5630 C CG . ASP B 1 110 ? 33.763 37.023 45.419 1.00 5.71 ? 110 ASP B CG 1 ATOM 5631 O OD1 . ASP B 1 110 ? 33.000 37.967 45.153 1.00 7.95 ? 110 ASP B OD1 1 ATOM 5632 O OD2 . ASP B 1 110 ? 33.834 36.505 46.545 1.00 7.87 ? 110 ASP B OD2 1 ATOM 5633 N N . LEU B 1 111 ? 33.522 37.912 41.601 1.00 2.21 ? 111 LEU B N 1 ATOM 5634 C CA . LEU B 1 111 ? 32.827 39.058 41.034 1.00 2.00 ? 111 LEU B CA 1 ATOM 5635 C C . LEU B 1 111 ? 31.819 38.818 39.886 1.00 2.00 ? 111 LEU B C 1 ATOM 5636 O O . LEU B 1 111 ? 30.764 39.446 39.892 1.00 2.76 ? 111 LEU B O 1 ATOM 5637 C CB . LEU B 1 111 ? 33.856 40.123 40.638 1.00 2.00 ? 111 LEU B CB 1 ATOM 5638 C CG . LEU B 1 111 ? 34.825 40.524 41.761 1.00 2.00 ? 111 LEU B CG 1 ATOM 5639 C CD1 . LEU B 1 111 ? 35.742 41.630 41.283 1.00 2.00 ? 111 LEU B CD1 1 ATOM 5640 C CD2 . LEU B 1 111 ? 34.052 40.980 42.976 1.00 2.00 ? 111 LEU B CD2 1 ATOM 5641 N N . ASP B 1 112 ? 32.088 37.936 38.915 1.00 2.00 ? 112 ASP B N 1 ATOM 5642 C CA . ASP B 1 112 ? 31.090 37.751 37.840 1.00 3.30 ? 112 ASP B CA 1 ATOM 5643 C C . ASP B 1 112 ? 30.872 36.385 37.177 1.00 2.97 ? 112 ASP B C 1 ATOM 5644 O O . ASP B 1 112 ? 31.712 35.499 37.239 1.00 2.36 ? 112 ASP B O 1 ATOM 5645 C CB . ASP B 1 112 ? 31.301 38.795 36.730 1.00 2.32 ? 112 ASP B CB 1 ATOM 5646 C CG . ASP B 1 112 ? 32.706 38.786 36.161 1.00 2.00 ? 112 ASP B CG 1 ATOM 5647 O OD1 . ASP B 1 112 ? 33.636 39.176 36.889 1.00 2.23 ? 112 ASP B OD1 1 ATOM 5648 O OD2 . ASP B 1 112 ? 32.884 38.392 34.990 1.00 2.00 ? 112 ASP B OD2 1 ATOM 5649 N N . PHE B 1 113 ? 29.715 36.234 36.533 1.00 4.45 ? 113 PHE B N 1 ATOM 5650 C CA . PHE B 1 113 ? 29.374 34.993 35.848 1.00 6.47 ? 113 PHE B CA 1 ATOM 5651 C C . PHE B 1 113 ? 28.129 35.149 34.984 1.00 7.39 ? 113 PHE B C 1 ATOM 5652 O O . PHE B 1 113 ? 27.010 35.239 35.496 1.00 6.78 ? 113 PHE B O 1 ATOM 5653 C CB . PHE B 1 113 ? 29.140 33.859 36.861 1.00 5.38 ? 113 PHE B CB 1 ATOM 5654 C CG . PHE B 1 113 ? 28.813 32.507 36.231 1.00 5.42 ? 113 PHE B CG 1 ATOM 5655 C CD1 . PHE B 1 113 ? 29.431 32.097 35.048 1.00 4.13 ? 113 PHE B CD1 1 ATOM 5656 C CD2 . PHE B 1 113 ? 27.976 31.607 36.889 1.00 5.00 ? 113 PHE B CD2 1 ATOM 5657 C CE1 . PHE B 1 113 ? 29.228 30.815 34.545 1.00 3.00 ? 113 PHE B CE1 1 ATOM 5658 C CE2 . PHE B 1 113 ? 27.770 30.328 36.393 1.00 4.42 ? 113 PHE B CE2 1 ATOM 5659 C CZ . PHE B 1 113 ? 28.400 29.929 35.220 1.00 3.32 ? 113 PHE B CZ 1 ATOM 5660 N N . ALA B 1 114 ? 28.321 35.172 33.671 1.00 7.55 ? 114 ALA B N 1 ATOM 5661 C CA . ALA B 1 114 ? 27.185 35.295 32.782 1.00 8.99 ? 114 ALA B CA 1 ATOM 5662 C C . ALA B 1 114 ? 26.848 33.902 32.236 1.00 10.42 ? 114 ALA B C 1 ATOM 5663 O O . ALA B 1 114 ? 27.515 33.383 31.325 1.00 10.27 ? 114 ALA B O 1 ATOM 5664 C CB . ALA B 1 114 ? 27.507 36.281 31.656 1.00 8.23 ? 114 ALA B CB 1 ATOM 5665 N N . PRO B 1 115 ? 25.803 33.275 32.790 1.00 11.95 ? 115 PRO B N 1 ATOM 5666 C CA . PRO B 1 115 ? 25.355 31.944 32.400 1.00 14.14 ? 115 PRO B CA 1 ATOM 5667 C C . PRO B 1 115 ? 25.182 31.780 30.914 1.00 18.01 ? 115 PRO B C 1 ATOM 5668 O O . PRO B 1 115 ? 24.713 32.683 30.225 1.00 18.71 ? 115 PRO B O 1 ATOM 5669 C CB . PRO B 1 115 ? 24.025 31.805 33.119 1.00 14.01 ? 115 PRO B CB 1 ATOM 5670 C CG . PRO B 1 115 ? 24.244 32.642 34.332 1.00 14.60 ? 115 PRO B CG 1 ATOM 5671 C CD . PRO B 1 115 ? 24.781 33.868 33.650 1.00 13.15 ? 115 PRO B CD 1 ATOM 5672 N N . GLU B 1 116 ? 25.570 30.617 30.423 1.00 21.77 ? 116 GLU B N 1 ATOM 5673 C CA . GLU B 1 116 ? 25.393 30.336 29.019 1.00 25.65 ? 116 GLU B CA 1 ATOM 5674 C C . GLU B 1 116 ? 23.913 29.961 28.997 1.00 27.66 ? 116 GLU B C 1 ATOM 5675 O O . GLU B 1 116 ? 23.341 29.627 30.042 1.00 27.56 ? 116 GLU B O 1 ATOM 5676 C CB . GLU B 1 116 ? 26.265 29.154 28.587 1.00 26.28 ? 116 GLU B CB 1 ATOM 5677 C CG . GLU B 1 116 ? 26.937 29.354 27.229 1.00 26.86 ? 116 GLU B CG 1 ATOM 5678 C CD . GLU B 1 116 ? 28.144 28.453 27.015 1.00 27.35 ? 116 GLU B CD 1 ATOM 5679 O OE1 . GLU B 1 116 ? 27.990 27.213 27.037 1.00 28.18 ? 116 GLU B OE1 1 ATOM 5680 O OE2 . GLU B 1 116 ? 29.253 28.993 26.818 1.00 27.55 ? 116 GLU B OE2 1 ATOM 5681 N N . THR B 1 117 ? 23.286 30.048 27.833 1.00 29.59 ? 117 THR B N 1 ATOM 5682 C CA . THR B 1 117 ? 21.911 29.674 27.704 1.00 32.45 ? 117 THR B CA 1 ATOM 5683 C C . THR B 1 117 ? 21.797 28.298 27.101 1.00 37.16 ? 117 THR B C 1 ATOM 5684 O O . THR B 1 117 ? 22.351 28.041 26.023 1.00 37.81 ? 117 THR B O 1 ATOM 5685 C CB . THR B 1 117 ? 21.198 30.564 26.687 1.00 31.27 ? 117 THR B CB 1 ATOM 5686 O OG1 . THR B 1 117 ? 21.892 30.499 25.430 1.00 31.03 ? 117 THR B OG1 1 ATOM 5687 C CG2 . THR B 1 117 ? 21.162 31.996 27.192 1.00 31.78 ? 117 THR B CG2 1 ATOM 5688 N N . GLU B 1 118 ? 21.123 27.508 27.818 1.00 42.80 ? 118 GLU B N 1 ATOM 5689 C CA . GLU B 1 118 ? 20.848 26.183 27.489 1.00 46.63 ? 118 GLU B CA 1 ATOM 5690 C C . GLU B 1 118 ? 19.487 26.033 28.021 1.00 50.78 ? 118 GLU B C 1 ATOM 5691 O O . GLU B 1 118 ? 19.317 25.962 29.230 1.00 50.78 ? 118 GLU B O 1 ATOM 5692 C CB . GLU B 1 118 ? 21.648 25.195 28.299 1.00 45.95 ? 118 GLU B CB 1 ATOM 5693 C CG . GLU B 1 118 ? 21.711 23.813 27.777 1.00 46.02 ? 118 GLU B CG 1 ATOM 5694 C CD . GLU B 1 118 ? 23.126 23.395 27.938 1.00 47.97 ? 118 GLU B CD 1 ATOM 5695 O OE1 . GLU B 1 118 ? 23.441 22.579 28.826 1.00 48.93 ? 118 GLU B OE1 1 ATOM 5696 O OE2 . GLU B 1 118 ? 23.975 23.883 27.144 1.00 47.79 ? 118 GLU B OE2 1 ATOM 5697 N N . LEU B 1 119 ? 18.545 26.029 27.178 1.00 53.75 ? 119 LEU B N 1 ATOM 5698 C CA . LEU B 1 119 ? 17.309 25.569 27.681 1.00 55.67 ? 119 LEU B CA 1 ATOM 5699 C C . LEU B 1 119 ? 17.544 24.197 27.143 1.00 58.16 ? 119 LEU B C 1 ATOM 5700 O O . LEU B 1 119 ? 18.467 24.091 26.327 1.00 57.74 ? 119 LEU B O 1 ATOM 5701 C CB . LEU B 1 119 ? 16.092 26.203 27.055 1.00 55.54 ? 119 LEU B CB 1 ATOM 5702 C CG . LEU B 1 119 ? 16.230 27.688 26.707 1.00 56.00 ? 119 LEU B CG 1 ATOM 5703 C CD1 . LEU B 1 119 ? 17.335 28.319 27.529 1.00 55.42 ? 119 LEU B CD1 1 ATOM 5704 C CD2 . LEU B 1 119 ? 16.497 27.872 25.231 1.00 56.41 ? 119 LEU B CD2 1 ATOM 5705 N N . GLY B 1 120 ? 16.854 23.132 27.440 1.00 60.54 ? 120 GLY B N 1 ATOM 5706 C CA . GLY B 1 120 ? 17.423 21.967 26.831 1.00 63.66 ? 120 GLY B CA 1 ATOM 5707 C C . GLY B 1 120 ? 18.333 21.324 27.856 1.00 65.08 ? 120 GLY B C 1 ATOM 5708 O O . GLY B 1 120 ? 19.381 21.834 28.250 1.00 65.09 ? 120 GLY B O 1 ATOM 5709 N N . SER B 1 121 ? 17.761 20.149 28.230 1.00 65.77 ? 121 SER B N 1 ATOM 5710 C CA . SER B 1 121 ? 18.218 19.120 29.204 1.00 66.96 ? 121 SER B CA 1 ATOM 5711 C C . SER B 1 121 ? 17.677 17.641 28.948 1.00 67.61 ? 121 SER B C 1 ATOM 5712 O O . SER B 1 121 ? 17.719 16.780 29.840 1.00 68.05 ? 121 SER B O 1 ATOM 5713 C CB . SER B 1 121 ? 17.845 19.559 30.612 1.00 66.71 ? 121 SER B CB 1 ATOM 5714 O OG . SER B 1 121 ? 17.969 18.490 31.538 1.00 66.31 ? 121 SER B OG 1 ATOM 5715 N N . SER B 1 122 ? 17.197 17.413 27.760 1.00 67.87 ? 122 SER B N 1 ATOM 5716 C CA . SER B 1 122 ? 16.744 16.232 27.092 1.00 68.12 ? 122 SER B CA 1 ATOM 5717 C C . SER B 1 122 ? 17.312 16.727 25.625 1.00 67.81 ? 122 SER B C 1 ATOM 5718 O O . SER B 1 122 ? 18.222 16.060 25.104 1.00 68.14 ? 122 SER B O 1 ATOM 5719 C CB . SER B 1 122 ? 15.260 15.856 27.380 1.00 68.64 ? 122 SER B CB 1 ATOM 5720 O OG . SER B 1 122 ? 15.150 15.152 28.608 1.00 69.46 ? 122 SER B OG 1 ATOM 5721 N N . GLU B 1 123 ? 16.814 17.860 24.952 1.00 66.61 ? 123 GLU B N 1 ATOM 5722 C CA . GLU B 1 123 ? 17.098 18.599 23.597 1.00 64.45 ? 123 GLU B CA 1 ATOM 5723 C C . GLU B 1 123 ? 18.062 18.103 22.454 1.00 62.46 ? 123 GLU B C 1 ATOM 5724 O O . GLU B 1 123 ? 19.107 17.501 22.687 1.00 62.19 ? 123 GLU B O 1 ATOM 5725 C CB . GLU B 1 123 ? 17.477 20.042 23.933 1.00 65.37 ? 123 GLU B CB 1 ATOM 5726 C CG . GLU B 1 123 ? 17.599 20.921 22.702 1.00 65.72 ? 123 GLU B CG 1 ATOM 5727 C CD . GLU B 1 123 ? 16.753 22.180 22.846 1.00 66.50 ? 123 GLU B CD 1 ATOM 5728 O OE1 . GLU B 1 123 ? 15.773 22.139 23.609 1.00 66.65 ? 123 GLU B OE1 1 ATOM 5729 O OE2 . GLU B 1 123 ? 17.084 23.203 22.205 1.00 67.21 ? 123 GLU B OE2 1 ATOM 5730 N N . HIS B 1 124 ? 17.675 18.435 21.185 1.00 59.54 ? 124 HIS B N 1 ATOM 5731 C CA . HIS B 1 124 ? 18.401 18.162 19.916 1.00 57.71 ? 124 HIS B CA 1 ATOM 5732 C C . HIS B 1 124 ? 18.692 19.490 19.165 1.00 55.92 ? 124 HIS B C 1 ATOM 5733 O O . HIS B 1 124 ? 19.505 19.486 18.242 1.00 56.03 ? 124 HIS B O 1 ATOM 5734 C CB . HIS B 1 124 ? 17.595 17.282 18.981 1.00 57.10 ? 124 HIS B CB 1 ATOM 5735 C CG . HIS B 1 124 ? 18.113 15.991 18.236 1.00 55.94 ? 124 HIS B CG 1 ATOM 5736 N ND1 . HIS B 1 124 ? 17.169 15.278 17.550 1.00 54.62 ? 124 HIS B ND1 1 ATOM 5737 C CD2 . HIS B 1 124 ? 19.272 15.298 18.068 1.00 55.29 ? 124 HIS B CD2 1 ATOM 5738 C CE1 . HIS B 1 124 ? 17.694 14.213 16.989 1.00 54.32 ? 124 HIS B CE1 1 ATOM 5739 N NE2 . HIS B 1 124 ? 18.975 14.195 17.294 1.00 54.90 ? 124 HIS B NE2 1 ATOM 5740 N N . SER B 1 125 ? 18.065 20.649 19.531 1.00 52.98 ? 125 SER B N 1 ATOM 5741 C CA . SER B 1 125 ? 18.462 21.964 18.999 1.00 50.84 ? 125 SER B CA 1 ATOM 5742 C C . SER B 1 125 ? 19.858 22.193 19.570 1.00 49.25 ? 125 SER B C 1 ATOM 5743 O O . SER B 1 125 ? 20.665 22.943 19.019 1.00 49.56 ? 125 SER B O 1 ATOM 5744 C CB . SER B 1 125 ? 17.516 23.094 19.454 1.00 50.96 ? 125 SER B CB 1 ATOM 5745 O OG . SER B 1 125 ? 16.256 22.995 18.800 1.00 50.76 ? 125 SER B OG 1 ATOM 5746 N N . LYS B 1 126 ? 20.082 21.526 20.695 1.00 46.06 ? 126 LYS B N 1 ATOM 5747 C CA . LYS B 1 126 ? 21.362 21.536 21.380 1.00 42.86 ? 126 LYS B CA 1 ATOM 5748 C C . LYS B 1 126 ? 22.319 20.888 20.380 1.00 42.52 ? 126 LYS B C 1 ATOM 5749 O O . LYS B 1 126 ? 23.506 21.201 20.331 1.00 42.16 ? 126 LYS B O 1 ATOM 5750 C CB . LYS B 1 126 ? 21.243 20.672 22.633 1.00 41.15 ? 126 LYS B CB 1 ATOM 5751 C CG . LYS B 1 126 ? 22.352 20.802 23.652 1.00 39.63 ? 126 LYS B CG 1 ATOM 5752 C CD . LYS B 1 126 ? 22.067 19.882 24.843 1.00 38.42 ? 126 LYS B CD 1 ATOM 5753 C CE . LYS B 1 126 ? 20.710 20.187 25.468 1.00 37.15 ? 126 LYS B CE 1 ATOM 5754 N NZ . LYS B 1 126 ? 20.297 19.163 26.458 1.00 35.68 ? 126 LYS B NZ 1 ATOM 5755 N N . VAL B 1 127 ? 21.764 19.997 19.563 1.00 42.46 ? 127 VAL B N 1 ATOM 5756 C CA . VAL B 1 127 ? 22.518 19.254 18.559 1.00 42.13 ? 127 VAL B CA 1 ATOM 5757 C C . VAL B 1 127 ? 22.549 19.864 17.155 1.00 42.02 ? 127 VAL B C 1 ATOM 5758 O O . VAL B 1 127 ? 23.460 19.564 16.374 1.00 40.91 ? 127 VAL B O 1 ATOM 5759 C CB . VAL B 1 127 ? 21.991 17.806 18.462 1.00 42.00 ? 127 VAL B CB 1 ATOM 5760 C CG1 . VAL B 1 127 ? 22.738 17.041 17.379 1.00 42.51 ? 127 VAL B CG1 1 ATOM 5761 C CG2 . VAL B 1 127 ? 22.151 17.115 19.811 1.00 42.62 ? 127 VAL B CG2 1 ATOM 5762 N N . GLN B 1 128 ? 21.568 20.701 16.814 1.00 42.07 ? 128 GLN B N 1 ATOM 5763 C CA . GLN B 1 128 ? 21.586 21.312 15.487 1.00 41.38 ? 128 GLN B CA 1 ATOM 5764 C C . GLN B 1 128 ? 22.771 22.268 15.438 1.00 38.75 ? 128 GLN B C 1 ATOM 5765 O O . GLN B 1 128 ? 23.179 22.721 14.366 1.00 37.75 ? 128 GLN B O 1 ATOM 5766 C CB . GLN B 1 128 ? 20.283 22.069 15.158 1.00 45.12 ? 128 GLN B CB 1 ATOM 5767 C CG . GLN B 1 128 ? 20.372 22.770 13.783 1.00 52.09 ? 128 GLN B CG 1 ATOM 5768 C CD . GLN B 1 128 ? 19.039 23.220 13.160 1.00 55.22 ? 128 GLN B CD 1 ATOM 5769 O OE1 . GLN B 1 128 ? 19.029 23.826 12.079 1.00 57.40 ? 128 GLN B OE1 1 ATOM 5770 N NE2 . GLN B 1 128 ? 17.922 22.922 13.824 1.00 57.60 ? 128 GLN B NE2 1 ATOM 5771 N N . CYS B 1 129 ? 23.333 22.559 16.609 1.00 34.60 ? 129 CYS B N 1 ATOM 5772 C CA . CYS B 1 129 ? 24.486 23.444 16.685 1.00 30.68 ? 129 CYS B CA 1 ATOM 5773 C C . CYS B 1 129 ? 25.789 22.633 16.756 1.00 30.59 ? 129 CYS B C 1 ATOM 5774 O O . CYS B 1 129 ? 26.712 22.893 15.986 1.00 32.79 ? 129 CYS B O 1 ATOM 5775 C CB . CYS B 1 129 ? 24.363 24.383 17.886 1.00 27.08 ? 129 CYS B CB 1 ATOM 5776 S SG . CYS B 1 129 ? 25.323 25.938 17.790 1.00 22.08 ? 129 CYS B SG 1 ATOM 5777 N N . GLU B 1 130 ? 25.889 21.643 17.640 1.00 27.37 ? 130 GLU B N 1 ATOM 5778 C CA . GLU B 1 130 ? 27.140 20.899 17.677 1.00 24.21 ? 130 GLU B CA 1 ATOM 5779 C C . GLU B 1 130 ? 27.354 20.101 16.381 1.00 24.79 ? 130 GLU B C 1 ATOM 5780 O O . GLU B 1 130 ? 28.490 19.979 15.929 1.00 25.36 ? 130 GLU B O 1 ATOM 5781 C CB . GLU B 1 130 ? 27.223 19.953 18.902 1.00 23.21 ? 130 GLU B CB 1 ATOM 5782 C CG . GLU B 1 130 ? 28.687 19.514 19.251 1.00 21.29 ? 130 GLU B CG 1 ATOM 5783 C CD . GLU B 1 130 ? 28.811 18.450 20.360 1.00 19.55 ? 130 GLU B CD 1 ATOM 5784 O OE1 . GLU B 1 130 ? 29.950 18.199 20.824 1.00 15.99 ? 130 GLU B OE1 1 ATOM 5785 O OE2 . GLU B 1 130 ? 27.786 17.865 20.766 1.00 19.09 ? 130 GLU B OE2 1 ATOM 5786 N N . GLU B 1 131 ? 26.284 19.603 15.752 1.00 24.25 ? 131 GLU B N 1 ATOM 5787 C CA . GLU B 1 131 ? 26.444 18.775 14.539 1.00 24.55 ? 131 GLU B CA 1 ATOM 5788 C C . GLU B 1 131 ? 26.275 19.381 13.129 1.00 22.89 ? 131 GLU B C 1 ATOM 5789 O O . GLU B 1 131 ? 26.791 18.822 12.159 1.00 22.07 ? 131 GLU B O 1 ATOM 5790 C CB . GLU B 1 131 ? 25.533 17.532 14.619 1.00 27.11 ? 131 GLU B CB 1 ATOM 5791 C CG . GLU B 1 131 ? 25.669 16.631 15.873 1.00 29.72 ? 131 GLU B CG 1 ATOM 5792 C CD . GLU B 1 131 ? 26.935 15.772 15.905 1.00 30.67 ? 131 GLU B CD 1 ATOM 5793 O OE1 . GLU B 1 131 ? 27.307 15.205 14.854 1.00 30.91 ? 131 GLU B OE1 1 ATOM 5794 O OE2 . GLU B 1 131 ? 27.545 15.648 16.993 1.00 31.76 ? 131 GLU B OE2 1 ATOM 5795 N N . TYR B 1 132 ? 25.558 20.493 12.993 1.00 21.73 ? 132 TYR B N 1 ATOM 5796 C CA . TYR B 1 132 ? 25.355 21.081 11.662 1.00 19.80 ? 132 TYR B CA 1 ATOM 5797 C C . TYR B 1 132 ? 25.919 22.491 11.466 1.00 18.32 ? 132 TYR B C 1 ATOM 5798 O O . TYR B 1 132 ? 25.992 22.995 10.339 1.00 17.42 ? 132 TYR B O 1 ATOM 5799 C CB . TYR B 1 132 ? 23.865 21.081 11.307 1.00 21.08 ? 132 TYR B CB 1 ATOM 5800 C CG . TYR B 1 132 ? 23.267 19.701 11.199 1.00 22.21 ? 132 TYR B CG 1 ATOM 5801 C CD1 . TYR B 1 132 ? 22.489 19.174 12.228 1.00 23.63 ? 132 TYR B CD1 1 ATOM 5802 C CD2 . TYR B 1 132 ? 23.499 18.909 10.079 1.00 23.11 ? 132 TYR B CD2 1 ATOM 5803 C CE1 . TYR B 1 132 ? 21.955 17.888 12.145 1.00 24.37 ? 132 TYR B CE1 1 ATOM 5804 C CE2 . TYR B 1 132 ? 22.972 17.621 9.985 1.00 24.08 ? 132 TYR B CE2 1 ATOM 5805 C CZ . TYR B 1 132 ? 22.202 17.119 11.023 1.00 23.95 ? 132 TYR B CZ 1 ATOM 5806 O OH . TYR B 1 132 ? 21.685 15.849 10.950 1.00 24.53 ? 132 TYR B OH 1 ATOM 5807 N N . CYS B 1 133 ? 26.320 23.121 12.562 1.00 15.51 ? 133 CYS B N 1 ATOM 5808 C CA . CYS B 1 133 ? 26.878 24.463 12.508 1.00 13.52 ? 133 CYS B CA 1 ATOM 5809 C C . CYS B 1 133 ? 25.966 25.433 11.761 1.00 14.35 ? 133 CYS B C 1 ATOM 5810 O O . CYS B 1 133 ? 26.368 26.075 10.786 1.00 15.46 ? 133 CYS B O 1 ATOM 5811 C CB . CYS B 1 133 ? 28.268 24.435 11.861 1.00 11.56 ? 133 CYS B CB 1 ATOM 5812 S SG . CYS B 1 133 ? 29.501 23.445 12.768 1.00 7.17 ? 133 CYS B SG 1 ATOM 5813 N N . ILE B 1 134 ? 24.731 25.533 12.236 1.00 14.20 ? 134 ILE B N 1 ATOM 5814 C CA . ILE B 1 134 ? 23.746 26.426 11.648 1.00 12.94 ? 134 ILE B CA 1 ATOM 5815 C C . ILE B 1 134 ? 23.371 27.525 12.648 1.00 13.89 ? 134 ILE B C 1 ATOM 5816 O O . ILE B 1 134 ? 22.848 27.250 13.730 1.00 12.44 ? 134 ILE B O 1 ATOM 5817 C CB . ILE B 1 134 ? 22.468 25.643 11.241 1.00 11.73 ? 134 ILE B CB 1 ATOM 5818 C CG1 . ILE B 1 134 ? 22.592 25.167 9.797 1.00 9.58 ? 134 ILE B CG1 1 ATOM 5819 C CG2 . ILE B 1 134 ? 21.230 26.496 11.450 1.00 12.38 ? 134 ILE B CG2 1 ATOM 5820 C CD1 . ILE B 1 134 ? 22.952 23.724 9.676 1.00 8.50 ? 134 ILE B CD1 1 ATOM 5821 N N . GLN B 1 135 ? 23.652 28.705 12.174 1.00 15.17 ? 135 GLN B N 1 ATOM 5822 C CA . GLN B 1 135 ? 23.308 29.882 12.891 1.00 16.49 ? 135 GLN B CA 1 ATOM 5823 C C . GLN B 1 135 ? 21.830 30.052 12.813 1.00 16.39 ? 135 GLN B C 1 ATOM 5824 O O . GLN B 1 135 ? 21.210 29.907 11.767 1.00 16.55 ? 135 GLN B O 1 ATOM 5825 C CB . GLN B 1 135 ? 23.941 31.118 12.245 1.00 17.89 ? 135 GLN B CB 1 ATOM 5826 C CG . GLN B 1 135 ? 24.286 32.291 13.110 1.00 20.98 ? 135 GLN B CG 1 ATOM 5827 C CD . GLN B 1 135 ? 25.278 33.109 12.293 1.00 24.20 ? 135 GLN B CD 1 ATOM 5828 O OE1 . GLN B 1 135 ? 26.490 32.840 12.302 1.00 26.80 ? 135 GLN B OE1 1 ATOM 5829 N NE2 . GLN B 1 135 ? 24.990 34.145 11.531 1.00 23.97 ? 135 GLN B NE2 1 ATOM 5830 N N . GLY B 1 136 ? 21.264 30.420 13.955 1.00 15.86 ? 136 GLY B N 1 ATOM 5831 C CA . GLY B 1 136 ? 19.839 30.644 14.150 1.00 17.04 ? 136 GLY B CA 1 ATOM 5832 C C . GLY B 1 136 ? 19.490 30.490 15.663 1.00 18.74 ? 136 GLY B C 1 ATOM 5833 O O . GLY B 1 136 ? 19.883 29.498 16.269 1.00 20.30 ? 136 GLY B O 1 ATOM 5834 N N . ASP B 1 137 ? 18.747 31.435 16.252 1.00 18.20 ? 137 ASP B N 1 ATOM 5835 C CA . ASP B 1 137 ? 18.435 31.489 17.723 1.00 18.57 ? 137 ASP B CA 1 ATOM 5836 C C . ASP B 1 137 ? 19.719 31.584 18.564 1.00 17.63 ? 137 ASP B C 1 ATOM 5837 O O . ASP B 1 137 ? 20.679 32.246 18.167 1.00 15.35 ? 137 ASP B O 1 ATOM 5838 C CB . ASP B 1 137 ? 17.616 30.267 18.216 1.00 21.21 ? 137 ASP B CB 1 ATOM 5839 C CG . ASP B 1 137 ? 16.222 30.622 18.749 1.00 24.36 ? 137 ASP B CG 1 ATOM 5840 O OD1 . ASP B 1 137 ? 15.421 31.212 17.989 1.00 26.51 ? 137 ASP B OD1 1 ATOM 5841 O OD2 . ASP B 1 137 ? 15.940 30.322 19.925 1.00 26.17 ? 137 ASP B OD2 1 ATOM 5842 N N . ASN B 1 138 ? 19.753 30.948 19.707 1.00 17.11 ? 138 ASN B N 1 ATOM 5843 C CA . ASN B 1 138 ? 20.865 31.052 20.632 1.00 15.35 ? 138 ASN B CA 1 ATOM 5844 C C . ASN B 1 138 ? 22.218 30.446 20.164 1.00 14.38 ? 138 ASN B C 1 ATOM 5845 O O . ASN B 1 138 ? 23.232 30.612 20.816 1.00 14.14 ? 138 ASN B O 1 ATOM 5846 C CB . ASN B 1 138 ? 20.439 30.404 21.941 1.00 16.19 ? 138 ASN B CB 1 ATOM 5847 C CG . ASN B 1 138 ? 19.517 31.310 22.707 1.00 17.94 ? 138 ASN B CG 1 ATOM 5848 O OD1 . ASN B 1 138 ? 19.953 32.331 23.250 1.00 18.70 ? 138 ASN B OD1 1 ATOM 5849 N ND2 . ASN B 1 138 ? 18.235 30.957 22.766 1.00 17.51 ? 138 ASN B ND2 1 ATOM 5850 N N . CYS B 1 139 ? 22.194 29.747 19.032 1.00 12.34 ? 139 CYS B N 1 ATOM 5851 C CA . CYS B 1 139 ? 23.383 29.120 18.463 1.00 11.96 ? 139 CYS B CA 1 ATOM 5852 C C . CYS B 1 139 ? 24.102 30.144 17.596 1.00 9.95 ? 139 CYS B C 1 ATOM 5853 O O . CYS B 1 139 ? 23.545 30.651 16.618 1.00 10.22 ? 139 CYS B O 1 ATOM 5854 C CB . CYS B 1 139 ? 22.977 27.907 17.620 1.00 15.63 ? 139 CYS B CB 1 ATOM 5855 S SG . CYS B 1 139 ? 24.248 27.134 16.544 1.00 21.45 ? 139 CYS B SG 1 ATOM 5856 N N . PHE B 1 140 ? 25.341 30.448 17.962 1.00 5.44 ? 140 PHE B N 1 ATOM 5857 C CA . PHE B 1 140 ? 26.133 31.418 17.228 1.00 2.49 ? 140 PHE B CA 1 ATOM 5858 C C . PHE B 1 140 ? 27.533 30.856 17.010 1.00 3.11 ? 140 PHE B C 1 ATOM 5859 O O . PHE B 1 140 ? 28.512 31.362 17.544 1.00 2.99 ? 140 PHE B O 1 ATOM 5860 C CB . PHE B 1 140 ? 26.173 32.715 18.020 1.00 2.10 ? 140 PHE B CB 1 ATOM 5861 C CG . PHE B 1 140 ? 27.012 33.787 17.402 1.00 2.67 ? 140 PHE B CG 1 ATOM 5862 C CD1 . PHE B 1 140 ? 27.279 33.797 16.044 1.00 2.75 ? 140 PHE B CD1 1 ATOM 5863 C CD2 . PHE B 1 140 ? 27.509 34.818 18.185 1.00 2.83 ? 140 PHE B CD2 1 ATOM 5864 C CE1 . PHE B 1 140 ? 28.028 34.819 15.479 1.00 2.34 ? 140 PHE B CE1 1 ATOM 5865 C CE2 . PHE B 1 140 ? 28.254 35.840 17.628 1.00 3.06 ? 140 PHE B CE2 1 ATOM 5866 C CZ . PHE B 1 140 ? 28.514 35.841 16.271 1.00 2.68 ? 140 PHE B CZ 1 ATOM 5867 N N . PRO B 1 141 ? 27.634 29.792 16.201 1.00 4.12 ? 141 PRO B N 1 ATOM 5868 C CA . PRO B 1 141 ? 28.843 29.055 15.825 1.00 2.95 ? 141 PRO B CA 1 ATOM 5869 C C . PRO B 1 141 ? 30.097 29.863 15.514 1.00 3.52 ? 141 PRO B C 1 ATOM 5870 O O . PRO B 1 141 ? 30.026 30.957 14.950 1.00 3.56 ? 141 PRO B O 1 ATOM 5871 C CB . PRO B 1 141 ? 28.386 28.260 14.606 1.00 3.70 ? 141 PRO B CB 1 ATOM 5872 C CG . PRO B 1 141 ? 26.980 27.948 14.927 1.00 3.21 ? 141 PRO B CG 1 ATOM 5873 C CD . PRO B 1 141 ? 26.473 29.269 15.454 1.00 5.04 ? 141 PRO B CD 1 ATOM 5874 N N . ILE B 1 142 ? 31.244 29.290 15.877 1.00 3.46 ? 142 ILE B N 1 ATOM 5875 C CA . ILE B 1 142 ? 32.546 29.894 15.611 1.00 4.21 ? 142 ILE B CA 1 ATOM 5876 C C . ILE B 1 142 ? 33.124 29.155 14.400 1.00 5.88 ? 142 ILE B C 1 ATOM 5877 O O . ILE B 1 142 ? 33.718 28.087 14.540 1.00 6.56 ? 142 ILE B O 1 ATOM 5878 C CB . ILE B 1 142 ? 33.515 29.724 16.801 1.00 2.00 ? 142 ILE B CB 1 ATOM 5879 C CG1 . ILE B 1 142 ? 32.975 30.456 18.032 1.00 2.10 ? 142 ILE B CG1 1 ATOM 5880 C CG2 . ILE B 1 142 ? 34.875 30.270 16.429 1.00 2.00 ? 142 ILE B CG2 1 ATOM 5881 C CD1 . ILE B 1 142 ? 33.888 30.392 19.241 1.00 2.00 ? 142 ILE B CD1 1 ATOM 5882 N N . MET B 1 143 ? 32.932 29.720 13.212 1.00 5.82 ? 143 MET B N 1 ATOM 5883 C CA . MET B 1 143 ? 33.415 29.116 11.973 1.00 6.28 ? 143 MET B CA 1 ATOM 5884 C C . MET B 1 143 ? 34.944 29.070 11.895 1.00 8.27 ? 143 MET B C 1 ATOM 5885 O O . MET B 1 143 ? 35.630 29.804 12.614 1.00 8.25 ? 143 MET B O 1 ATOM 5886 C CB . MET B 1 143 ? 32.869 29.911 10.785 1.00 7.37 ? 143 MET B CB 1 ATOM 5887 C CG . MET B 1 143 ? 32.090 29.091 9.780 1.00 8.71 ? 143 MET B CG 1 ATOM 5888 S SD . MET B 1 143 ? 30.762 28.149 10.548 1.00 8.31 ? 143 MET B SD 1 ATOM 5889 C CE . MET B 1 143 ? 29.559 29.439 10.830 1.00 12.64 ? 143 MET B CE 1 ATOM 5890 N N . PHE B 1 144 ? 35.468 28.207 11.020 1.00 8.61 ? 144 PHE B N 1 ATOM 5891 C CA . PHE B 1 144 ? 36.923 28.065 10.809 1.00 7.70 ? 144 PHE B CA 1 ATOM 5892 C C . PHE B 1 144 ? 37.341 28.708 9.483 1.00 6.61 ? 144 PHE B C 1 ATOM 5893 O O . PHE B 1 144 ? 36.584 28.702 8.514 1.00 8.37 ? 144 PHE B O 1 ATOM 5894 C CB . PHE B 1 144 ? 37.359 26.586 10.704 1.00 7.46 ? 144 PHE B CB 1 ATOM 5895 C CG . PHE B 1 144 ? 37.116 25.751 11.944 1.00 8.34 ? 144 PHE B CG 1 ATOM 5896 C CD1 . PHE B 1 144 ? 37.569 26.162 13.195 1.00 8.69 ? 144 PHE B CD1 1 ATOM 5897 C CD2 . PHE B 1 144 ? 36.491 24.510 11.840 1.00 7.12 ? 144 PHE B CD2 1 ATOM 5898 C CE1 . PHE B 1 144 ? 37.402 25.341 14.318 1.00 7.86 ? 144 PHE B CE1 1 ATOM 5899 C CE2 . PHE B 1 144 ? 36.325 23.695 12.949 1.00 5.97 ? 144 PHE B CE2 1 ATOM 5900 C CZ . PHE B 1 144 ? 36.781 24.109 14.190 1.00 6.32 ? 144 PHE B CZ 1 ATOM 5901 N N . PRO B 1 145 ? 38.546 29.284 9.428 1.00 5.80 ? 145 PRO B N 1 ATOM 5902 C CA . PRO B 1 145 ? 39.009 29.892 8.177 1.00 7.28 ? 145 PRO B CA 1 ATOM 5903 C C . PRO B 1 145 ? 39.610 28.757 7.322 1.00 9.47 ? 145 PRO B C 1 ATOM 5904 O O . PRO B 1 145 ? 39.612 27.601 7.750 1.00 9.40 ? 145 PRO B O 1 ATOM 5905 C CB . PRO B 1 145 ? 40.064 30.883 8.653 1.00 6.62 ? 145 PRO B CB 1 ATOM 5906 C CG . PRO B 1 145 ? 40.635 30.197 9.857 1.00 5.28 ? 145 PRO B CG 1 ATOM 5907 C CD . PRO B 1 145 ? 39.385 29.716 10.558 1.00 4.87 ? 145 PRO B CD 1 ATOM 5908 N N . LYS B 1 146 ? 40.111 29.064 6.127 1.00 12.54 ? 146 LYS B N 1 ATOM 5909 C CA . LYS B 1 146 ? 40.716 28.026 5.274 1.00 15.11 ? 146 LYS B CA 1 ATOM 5910 C C . LYS B 1 146 ? 41.939 27.408 5.949 1.00 15.64 ? 146 LYS B C 1 ATOM 5911 O O . LYS B 1 146 ? 42.510 27.978 6.880 1.00 15.71 ? 146 LYS B O 1 ATOM 5912 C CB . LYS B 1 146 ? 41.190 28.600 3.933 1.00 17.18 ? 146 LYS B CB 1 ATOM 5913 C CG . LYS B 1 146 ? 40.118 29.091 2.982 1.00 21.56 ? 146 LYS B CG 1 ATOM 5914 C CD . LYS B 1 146 ? 40.763 29.644 1.700 1.00 24.94 ? 146 LYS B CD 1 ATOM 5915 C CE . LYS B 1 146 ? 41.686 28.616 1.030 1.00 26.54 ? 146 LYS B CE 1 ATOM 5916 N NZ . LYS B 1 146 ? 42.330 29.134 -0.217 1.00 28.48 ? 146 LYS B NZ 1 ATOM 5917 N N . ASN B 1 147 ? 42.350 26.250 5.453 1.00 15.17 ? 147 ASN B N 1 ATOM 5918 C CA . ASN B 1 147 ? 43.526 25.565 5.979 1.00 14.98 ? 147 ASN B CA 1 ATOM 5919 C C . ASN B 1 147 ? 43.757 25.704 7.490 1.00 11.71 ? 147 ASN B C 1 ATOM 5920 O O . ASN B 1 147 ? 44.864 26.028 7.931 1.00 9.83 ? 147 ASN B O 1 ATOM 5921 C CB . ASN B 1 147 ? 44.772 26.033 5.218 1.00 19.53 ? 147 ASN B CB 1 ATOM 5922 C CG . ASN B 1 147 ? 44.679 25.767 3.714 1.00 23.04 ? 147 ASN B CG 1 ATOM 5923 O OD1 . ASN B 1 147 ? 43.752 26.235 3.049 1.00 26.04 ? 147 ASN B OD1 1 ATOM 5924 N ND2 . ASN B 1 147 ? 45.640 25.015 3.176 1.00 23.68 ? 147 ASN B ND2 1 ATOM 5925 N N . ASP B 1 148 ? 42.699 25.483 8.271 1.00 8.37 ? 148 ASP B N 1 ATOM 5926 C CA . ASP B 1 148 ? 42.789 25.511 9.732 1.00 4.66 ? 148 ASP B CA 1 ATOM 5927 C C . ASP B 1 148 ? 42.883 24.035 10.058 1.00 2.69 ? 148 ASP B C 1 ATOM 5928 O O . ASP B 1 148 ? 41.943 23.277 9.835 1.00 2.00 ? 148 ASP B O 1 ATOM 5929 C CB . ASP B 1 148 ? 41.527 26.096 10.381 1.00 3.43 ? 148 ASP B CB 1 ATOM 5930 C CG . ASP B 1 148 ? 41.611 26.130 11.913 1.00 2.48 ? 148 ASP B CG 1 ATOM 5931 O OD1 . ASP B 1 148 ? 41.836 25.068 12.533 1.00 3.42 ? 148 ASP B OD1 1 ATOM 5932 O OD2 . ASP B 1 148 ? 41.450 27.220 12.499 1.00 2.00 ? 148 ASP B OD2 1 ATOM 5933 N N . PRO B 1 149 ? 43.997 23.632 10.697 1.00 2.00 ? 149 PRO B N 1 ATOM 5934 C CA . PRO B 1 149 ? 44.185 22.222 11.021 1.00 2.00 ? 149 PRO B CA 1 ATOM 5935 C C . PRO B 1 149 ? 42.949 21.544 11.587 1.00 2.51 ? 149 PRO B C 1 ATOM 5936 O O . PRO B 1 149 ? 42.649 20.400 11.271 1.00 3.50 ? 149 PRO B O 1 ATOM 5937 C CB . PRO B 1 149 ? 45.471 22.229 11.798 1.00 2.30 ? 149 PRO B CB 1 ATOM 5938 C CG . PRO B 1 149 ? 46.243 23.290 11.050 1.00 2.65 ? 149 PRO B CG 1 ATOM 5939 C CD . PRO B 1 149 ? 45.282 24.249 10.428 1.00 2.02 ? 149 PRO B CD 1 ATOM 5940 N N . LYS B 1 150 ? 42.215 22.268 12.450 1.00 2.04 ? 150 LYS B N 1 ATOM 5941 C CA . LYS B 1 150 ? 41.027 21.673 13.060 1.00 2.00 ? 150 LYS B CA 1 ATOM 5942 C C . LYS B 1 150 ? 40.117 21.067 11.950 1.00 2.12 ? 150 LYS B C 1 ATOM 5943 O O . LYS B 1 150 ? 39.421 20.065 12.186 1.00 2.99 ? 150 LYS B O 1 ATOM 5944 C CB . LYS B 1 150 ? 40.305 22.693 13.949 1.00 2.00 ? 150 LYS B CB 1 ATOM 5945 C CG . LYS B 1 150 ? 40.348 22.373 15.445 1.00 2.96 ? 150 LYS B CG 1 ATOM 5946 C CD . LYS B 1 150 ? 40.836 23.538 16.304 1.00 3.23 ? 150 LYS B CD 1 ATOM 5947 C CE . LYS B 1 150 ? 41.036 23.114 17.757 1.00 2.00 ? 150 LYS B CE 1 ATOM 5948 N NZ . LYS B 1 150 ? 41.853 21.869 17.867 1.00 2.00 ? 150 LYS B NZ 1 ATOM 5949 N N . LEU B 1 151 ? 40.115 21.622 10.762 1.00 2.00 ? 151 LEU B N 1 ATOM 5950 C CA . LEU B 1 151 ? 39.216 21.177 9.699 1.00 2.26 ? 151 LEU B CA 1 ATOM 5951 C C . LEU B 1 151 ? 39.220 19.697 9.335 1.00 3.85 ? 151 LEU B C 1 ATOM 5952 O O . LEU B 1 151 ? 38.169 19.089 9.117 1.00 3.40 ? 151 LEU B O 1 ATOM 5953 C CB . LEU B 1 151 ? 39.498 21.990 8.434 1.00 2.00 ? 151 LEU B CB 1 ATOM 5954 C CG . LEU B 1 151 ? 38.719 23.291 8.241 1.00 2.76 ? 151 LEU B CG 1 ATOM 5955 C CD1 . LEU B 1 151 ? 39.268 24.085 7.065 1.00 2.94 ? 151 LEU B CD1 1 ATOM 5956 C CD2 . LEU B 1 151 ? 37.236 23.002 8.055 1.00 2.25 ? 151 LEU B CD2 1 ATOM 5957 N N . LYS B 1 152 ? 40.419 19.131 9.283 1.00 4.05 ? 152 LYS B N 1 ATOM 5958 C CA . LYS B 1 152 ? 40.591 17.731 8.953 1.00 5.89 ? 152 LYS B CA 1 ATOM 5959 C C . LYS B 1 152 ? 40.282 16.887 10.195 1.00 8.69 ? 152 LYS B C 1 ATOM 5960 O O . LYS B 1 152 ? 40.119 15.664 10.102 1.00 10.63 ? 152 LYS B O 1 ATOM 5961 C CB . LYS B 1 152 ? 42.033 17.491 8.501 1.00 3.57 ? 152 LYS B CB 1 ATOM 5962 C CG . LYS B 1 152 ? 42.492 18.414 7.383 1.00 2.86 ? 152 LYS B CG 1 ATOM 5963 C CD . LYS B 1 152 ? 43.994 18.338 7.212 1.00 2.20 ? 152 LYS B CD 1 ATOM 5964 C CE . LYS B 1 152 ? 44.509 19.317 6.184 1.00 2.00 ? 152 LYS B CE 1 ATOM 5965 N NZ . LYS B 1 152 ? 45.990 19.215 6.136 1.00 2.19 ? 152 LYS B NZ 1 ATOM 5966 N N . THR B 1 153 ? 40.143 17.570 11.352 1.00 6.63 ? 153 THR B N 1 ATOM 5967 C CA . THR B 1 153 ? 39.924 16.779 12.587 1.00 5.31 ? 153 THR B CA 1 ATOM 5968 C C . THR B 1 153 ? 38.574 16.903 13.288 1.00 7.59 ? 153 THR B C 1 ATOM 5969 O O . THR B 1 153 ? 37.886 15.894 13.438 1.00 8.59 ? 153 THR B O 1 ATOM 5970 C CB . THR B 1 153 ? 41.010 17.135 13.608 1.00 3.06 ? 153 THR B CB 1 ATOM 5971 O OG1 . THR B 1 153 ? 42.214 16.443 13.258 1.00 3.89 ? 153 THR B OG1 1 ATOM 5972 C CG2 . THR B 1 153 ? 40.588 16.738 15.019 1.00 3.30 ? 153 THR B CG2 1 ATOM 5973 N N . GLN B 1 154 ? 38.159 18.093 13.668 1.00 7.33 ? 154 GLN B N 1 ATOM 5974 C CA . GLN B 1 154 ? 36.910 18.159 14.403 1.00 8.06 ? 154 GLN B CA 1 ATOM 5975 C C . GLN B 1 154 ? 35.634 18.521 13.679 1.00 9.88 ? 154 GLN B C 1 ATOM 5976 O O . GLN B 1 154 ? 34.553 18.170 14.169 1.00 10.41 ? 154 GLN B O 1 ATOM 5977 C CB . GLN B 1 154 ? 37.012 19.222 15.505 1.00 5.78 ? 154 GLN B CB 1 ATOM 5978 C CG . GLN B 1 154 ? 38.132 19.087 16.507 1.00 4.45 ? 154 GLN B CG 1 ATOM 5979 C CD . GLN B 1 154 ? 38.311 20.372 17.316 1.00 4.61 ? 154 GLN B CD 1 ATOM 5980 O OE1 . GLN B 1 154 ? 39.433 20.819 17.525 1.00 4.04 ? 154 GLN B OE1 1 ATOM 5981 N NE2 . GLN B 1 154 ? 37.356 21.118 17.850 1.00 6.02 ? 154 GLN B NE2 1 ATOM 5982 N N . GLY B 1 155 ? 35.664 19.206 12.567 1.00 9.85 ? 155 GLY B N 1 ATOM 5983 C CA . GLY B 1 155 ? 34.383 19.506 11.964 1.00 10.10 ? 155 GLY B CA 1 ATOM 5984 C C . GLY B 1 155 ? 34.474 20.766 11.159 1.00 9.58 ? 155 GLY B C 1 ATOM 5985 O O . GLY B 1 155 ? 35.532 21.112 10.635 1.00 9.05 ? 155 GLY B O 1 ATOM 5986 N N . LYS B 1 156 ? 33.361 21.487 11.064 1.00 8.31 ? 156 LYS B N 1 ATOM 5987 C CA . LYS B 1 156 ? 33.327 22.723 10.296 1.00 7.65 ? 156 LYS B CA 1 ATOM 5988 C C . LYS B 1 156 ? 33.283 23.912 11.248 1.00 5.92 ? 156 LYS B C 1 ATOM 5989 O O . LYS B 1 156 ? 33.451 25.058 10.834 1.00 5.93 ? 156 LYS B O 1 ATOM 5990 C CB . LYS B 1 156 ? 32.104 22.737 9.365 1.00 7.41 ? 156 LYS B CB 1 ATOM 5991 C CG . LYS B 1 156 ? 32.452 22.954 7.896 1.00 7.75 ? 156 LYS B CG 1 ATOM 5992 C CD . LYS B 1 156 ? 31.295 22.592 6.969 1.00 8.89 ? 156 LYS B CD 1 ATOM 5993 C CE . LYS B 1 156 ? 31.761 22.577 5.517 1.00 9.95 ? 156 LYS B CE 1 ATOM 5994 N NZ . LYS B 1 156 ? 32.927 21.653 5.312 1.00 9.15 ? 156 LYS B NZ 1 ATOM 5995 N N . CYS B 1 157 ? 33.082 23.642 12.531 1.00 3.99 ? 157 CYS B N 1 ATOM 5996 C CA . CYS B 1 157 ? 33.001 24.731 13.483 1.00 4.38 ? 157 CYS B CA 1 ATOM 5997 C C . CYS B 1 157 ? 33.024 24.249 14.924 1.00 5.69 ? 157 CYS B C 1 ATOM 5998 O O . CYS B 1 157 ? 33.079 23.046 15.198 1.00 7.03 ? 157 CYS B O 1 ATOM 5999 C CB . CYS B 1 157 ? 31.709 25.495 13.262 1.00 4.56 ? 157 CYS B CB 1 ATOM 6000 S SG . CYS B 1 157 ? 30.298 24.730 14.119 1.00 5.16 ? 157 CYS B SG 1 ATOM 6001 N N . MET B 1 158 ? 32.964 25.205 15.847 1.00 5.77 ? 158 MET B N 1 ATOM 6002 C CA . MET B 1 158 ? 32.960 24.884 17.263 1.00 3.96 ? 158 MET B CA 1 ATOM 6003 C C . MET B 1 158 ? 31.657 25.339 17.866 1.00 2.00 ? 158 MET B C 1 ATOM 6004 O O . MET B 1 158 ? 31.349 26.524 17.868 1.00 2.02 ? 158 MET B O 1 ATOM 6005 C CB . MET B 1 158 ? 34.081 25.604 18.007 1.00 4.70 ? 158 MET B CB 1 ATOM 6006 C CG . MET B 1 158 ? 35.465 25.423 17.443 1.00 5.10 ? 158 MET B CG 1 ATOM 6007 S SD . MET B 1 158 ? 36.558 26.466 18.414 1.00 10.65 ? 158 MET B SD 1 ATOM 6008 C CE . MET B 1 158 ? 37.754 25.305 18.978 1.00 7.71 ? 158 MET B CE 1 ATOM 6009 N N . PRO B 1 159 ? 30.855 24.401 18.360 1.00 2.00 ? 159 PRO B N 1 ATOM 6010 C CA . PRO B 1 159 ? 29.595 24.824 18.964 1.00 2.00 ? 159 PRO B CA 1 ATOM 6011 C C . PRO B 1 159 ? 29.842 25.989 19.933 1.00 2.30 ? 159 PRO B C 1 ATOM 6012 O O . PRO B 1 159 ? 30.858 26.033 20.625 1.00 2.24 ? 159 PRO B O 1 ATOM 6013 C CB . PRO B 1 159 ? 29.097 23.551 19.666 1.00 2.08 ? 159 PRO B CB 1 ATOM 6014 C CG . PRO B 1 159 ? 30.311 22.596 19.656 1.00 2.30 ? 159 PRO B CG 1 ATOM 6015 C CD . PRO B 1 159 ? 30.979 22.937 18.360 1.00 2.01 ? 159 PRO B CD 1 ATOM 6016 N N . PHE B 1 160 ? 28.912 26.939 19.957 1.00 3.40 ? 160 PHE B N 1 ATOM 6017 C CA . PHE B 1 160 ? 29.007 28.122 20.813 1.00 2.52 ? 160 PHE B CA 1 ATOM 6018 C C . PHE B 1 160 ? 27.616 28.739 20.989 1.00 3.65 ? 160 PHE B C 1 ATOM 6019 O O . PHE B 1 160 ? 26.887 28.924 20.015 1.00 5.18 ? 160 PHE B O 1 ATOM 6020 C CB . PHE B 1 160 ? 29.952 29.134 20.168 1.00 2.00 ? 160 PHE B CB 1 ATOM 6021 C CG . PHE B 1 160 ? 30.062 30.426 20.911 1.00 2.00 ? 160 PHE B CG 1 ATOM 6022 C CD1 . PHE B 1 160 ? 29.007 31.321 20.941 1.00 2.55 ? 160 PHE B CD1 1 ATOM 6023 C CD2 . PHE B 1 160 ? 31.234 30.758 21.569 1.00 2.85 ? 160 PHE B CD2 1 ATOM 6024 C CE1 . PHE B 1 160 ? 29.122 32.530 21.614 1.00 3.85 ? 160 PHE B CE1 1 ATOM 6025 C CE2 . PHE B 1 160 ? 31.360 31.964 22.245 1.00 3.17 ? 160 PHE B CE2 1 ATOM 6026 C CZ . PHE B 1 160 ? 30.302 32.852 22.268 1.00 3.36 ? 160 PHE B CZ 1 ATOM 6027 N N . PHE B 1 161 ? 27.248 29.068 22.222 1.00 2.83 ? 161 PHE B N 1 ATOM 6028 C CA . PHE B 1 161 ? 25.935 29.650 22.478 1.00 2.70 ? 161 PHE B CA 1 ATOM 6029 C C . PHE B 1 161 ? 25.971 31.049 23.076 1.00 2.51 ? 161 PHE B C 1 ATOM 6030 O O . PHE B 1 161 ? 26.970 31.450 23.667 1.00 3.27 ? 161 PHE B O 1 ATOM 6031 C CB . PHE B 1 161 ? 25.141 28.754 23.410 1.00 4.43 ? 161 PHE B CB 1 ATOM 6032 C CG . PHE B 1 161 ? 24.694 27.479 22.787 1.00 5.33 ? 161 PHE B CG 1 ATOM 6033 C CD1 . PHE B 1 161 ? 25.550 26.389 22.706 1.00 6.88 ? 161 PHE B CD1 1 ATOM 6034 C CD2 . PHE B 1 161 ? 23.398 27.356 22.307 1.00 6.52 ? 161 PHE B CD2 1 ATOM 6035 C CE1 . PHE B 1 161 ? 25.117 25.185 22.159 1.00 7.46 ? 161 PHE B CE1 1 ATOM 6036 C CE2 . PHE B 1 161 ? 22.953 26.164 21.757 1.00 7.36 ? 161 PHE B CE2 1 ATOM 6037 C CZ . PHE B 1 161 ? 23.811 25.073 21.684 1.00 7.57 ? 161 PHE B CZ 1 ATOM 6038 N N . ARG B 1 162 ? 24.865 31.781 22.949 1.00 2.00 ? 162 ARG B N 1 ATOM 6039 C CA . ARG B 1 162 ? 24.798 33.140 23.478 1.00 2.50 ? 162 ARG B CA 1 ATOM 6040 C C . ARG B 1 162 ? 24.528 33.196 24.965 1.00 2.00 ? 162 ARG B C 1 ATOM 6041 O O . ARG B 1 162 ? 23.781 32.385 25.504 1.00 2.21 ? 162 ARG B O 1 ATOM 6042 C CB . ARG B 1 162 ? 23.728 33.946 22.753 1.00 2.87 ? 162 ARG B CB 1 ATOM 6043 C CG . ARG B 1 162 ? 23.995 34.121 21.277 1.00 4.77 ? 162 ARG B CG 1 ATOM 6044 C CD . ARG B 1 162 ? 23.068 35.161 20.666 1.00 6.48 ? 162 ARG B CD 1 ATOM 6045 N NE . ARG B 1 162 ? 23.488 36.530 20.952 1.00 7.56 ? 162 ARG B NE 1 ATOM 6046 C CZ . ARG B 1 162 ? 22.874 37.602 20.468 1.00 8.03 ? 162 ARG B CZ 1 ATOM 6047 N NH1 . ARG B 1 162 ? 21.816 37.450 19.686 1.00 9.57 ? 162 ARG B NH1 1 ATOM 6048 N NH2 . ARG B 1 162 ? 23.325 38.819 20.745 1.00 8.84 ? 162 ARG B NH2 1 ATOM 6049 N N . ALA B 1 163 ? 25.131 34.178 25.621 1.00 2.00 ? 163 ALA B N 1 ATOM 6050 C CA . ALA B 1 163 ? 24.968 34.356 27.062 1.00 3.10 ? 163 ALA B CA 1 ATOM 6051 C C . ALA B 1 163 ? 23.580 34.864 27.436 1.00 2.00 ? 163 ALA B C 1 ATOM 6052 O O . ALA B 1 163 ? 23.087 35.820 26.851 1.00 2.63 ? 163 ALA B O 1 ATOM 6053 C CB . ALA B 1 163 ? 26.024 35.325 27.581 1.00 4.02 ? 163 ALA B CB 1 ATOM 6054 N N . GLY B 1 164 ? 22.962 34.239 28.428 1.00 2.00 ? 164 GLY B N 1 ATOM 6055 C CA . GLY B 1 164 ? 21.636 34.665 28.848 1.00 4.06 ? 164 GLY B CA 1 ATOM 6056 C C . GLY B 1 164 ? 21.491 36.160 29.066 1.00 5.78 ? 164 GLY B C 1 ATOM 6057 O O . GLY B 1 164 ? 22.440 36.822 29.497 1.00 6.81 ? 164 GLY B O 1 ATOM 6058 N N . PHE B 1 165 ? 20.304 36.690 28.771 1.00 5.50 ? 165 PHE B N 1 ATOM 6059 C CA . PHE B 1 165 ? 20.029 38.112 28.928 1.00 5.47 ? 165 PHE B CA 1 ATOM 6060 C C . PHE B 1 165 ? 18.966 38.322 29.972 1.00 7.31 ? 165 PHE B C 1 ATOM 6061 O O . PHE B 1 165 ? 18.356 37.366 30.442 1.00 6.89 ? 165 PHE B O 1 ATOM 6062 C CB . PHE B 1 165 ? 19.573 38.744 27.604 1.00 6.32 ? 165 PHE B CB 1 ATOM 6063 C CG . PHE B 1 165 ? 18.849 37.798 26.672 1.00 6.57 ? 165 PHE B CG 1 ATOM 6064 C CD1 . PHE B 1 165 ? 19.536 36.776 26.021 1.00 7.24 ? 165 PHE B CD1 1 ATOM 6065 C CD2 . PHE B 1 165 ? 17.486 37.950 26.418 1.00 6.00 ? 165 PHE B CD2 1 ATOM 6066 C CE1 . PHE B 1 165 ? 18.880 35.923 25.130 1.00 7.36 ? 165 PHE B CE1 1 ATOM 6067 C CE2 . PHE B 1 165 ? 16.824 37.102 25.529 1.00 5.80 ? 165 PHE B CE2 1 ATOM 6068 C CZ . PHE B 1 165 ? 17.522 36.089 24.885 1.00 6.17 ? 165 PHE B CZ 1 ATOM 6069 N N . VAL B 1 166 ? 18.731 39.571 30.349 1.00 10.80 ? 166 VAL B N 1 ATOM 6070 C CA . VAL B 1 166 ? 17.715 39.800 31.352 1.00 16.03 ? 166 VAL B CA 1 ATOM 6071 C C . VAL B 1 166 ? 16.387 39.343 30.826 1.00 22.66 ? 166 VAL B C 1 ATOM 6072 O O . VAL B 1 166 ? 16.230 39.104 29.625 1.00 23.21 ? 166 VAL B O 1 ATOM 6073 C CB . VAL B 1 166 ? 17.561 41.277 31.768 1.00 14.29 ? 166 VAL B CB 1 ATOM 6074 C CG1 . VAL B 1 166 ? 18.837 41.769 32.356 1.00 13.64 ? 166 VAL B CG1 1 ATOM 6075 C CG2 . VAL B 1 166 ? 17.121 42.128 30.592 1.00 14.74 ? 166 VAL B CG2 1 ATOM 6076 N N . CYS B 1 167 ? 15.436 39.224 31.747 1.00 31.24 ? 167 CYS B N 1 ATOM 6077 C CA . CYS B 1 167 ? 14.084 38.787 31.424 1.00 37.09 ? 167 CYS B CA 1 ATOM 6078 C C . CYS B 1 167 ? 14.269 37.281 31.083 1.00 40.39 ? 167 CYS B C 1 ATOM 6079 O O . CYS B 1 167 ? 15.137 36.604 31.688 1.00 38.94 ? 167 CYS B O 1 ATOM 6080 C CB . CYS B 1 167 ? 13.554 39.689 30.255 1.00 41.88 ? 167 CYS B CB 1 ATOM 6081 S SG . CYS B 1 167 ? 13.926 41.506 30.452 1.00 52.85 ? 167 CYS B SG 1 ATOM 6082 N N . PRO B 1 168 ? 13.475 36.714 30.151 1.00 40.66 ? 168 PRO B N 1 ATOM 6083 C CA . PRO B 1 168 ? 13.792 35.289 29.952 1.00 42.88 ? 168 PRO B CA 1 ATOM 6084 C C . PRO B 1 168 ? 15.182 34.852 29.426 1.00 45.51 ? 168 PRO B C 1 ATOM 6085 O O . PRO B 1 168 ? 16.168 34.856 30.152 1.00 45.55 ? 168 PRO B O 1 ATOM 6086 C CB . PRO B 1 168 ? 12.674 34.820 29.008 1.00 42.46 ? 168 PRO B CB 1 ATOM 6087 C CG . PRO B 1 168 ? 11.516 35.657 29.403 1.00 42.23 ? 168 PRO B CG 1 ATOM 6088 C CD . PRO B 1 168 ? 12.210 37.033 29.463 1.00 40.39 ? 168 PRO B CD 1 ATOM 6089 N N . THR B 1 169 ? 15.200 34.426 28.162 1.00 49.28 ? 169 THR B N 1 ATOM 6090 C CA . THR B 1 169 ? 16.367 33.964 27.384 1.00 52.94 ? 169 THR B CA 1 ATOM 6091 C C . THR B 1 169 ? 15.764 33.428 26.082 1.00 56.20 ? 169 THR B C 1 ATOM 6092 O O . THR B 1 169 ? 16.353 33.588 25.003 1.00 56.20 ? 169 THR B O 1 ATOM 6093 C CB . THR B 1 169 ? 17.195 32.866 28.095 1.00 52.70 ? 169 THR B CB 1 ATOM 6094 O OG1 . THR B 1 169 ? 16.412 32.236 29.110 1.00 53.64 ? 169 THR B OG1 1 ATOM 6095 C CG2 . THR B 1 169 ? 18.452 33.471 28.705 1.00 52.42 ? 169 THR B CG2 1 ATOM 6096 N N . PRO B 1 170 ? 14.569 32.792 26.168 1.00 59.51 ? 170 PRO B N 1 ATOM 6097 C CA . PRO B 1 170 ? 13.839 32.238 25.016 1.00 61.57 ? 170 PRO B CA 1 ATOM 6098 C C . PRO B 1 170 ? 13.456 33.398 24.062 1.00 63.13 ? 170 PRO B C 1 ATOM 6099 O O . PRO B 1 170 ? 13.978 34.504 24.215 1.00 63.50 ? 170 PRO B O 1 ATOM 6100 C CB . PRO B 1 170 ? 12.637 31.553 25.687 1.00 61.27 ? 170 PRO B CB 1 ATOM 6101 C CG . PRO B 1 170 ? 13.282 30.972 26.912 1.00 61.13 ? 170 PRO B CG 1 ATOM 6102 C CD . PRO B 1 170 ? 14.035 32.205 27.411 1.00 59.74 ? 170 PRO B CD 1 ATOM 6103 N N . PRO B 1 171 ? 12.384 33.217 23.179 1.00 64.34 ? 171 PRO B N 1 ATOM 6104 C CA . PRO B 1 171 ? 11.998 34.185 22.047 1.00 65.49 ? 171 PRO B CA 1 ATOM 6105 C C . PRO B 1 171 ? 12.073 35.757 22.150 1.00 66.33 ? 171 PRO B C 1 ATOM 6106 O O . PRO B 1 171 ? 11.183 36.467 21.681 1.00 67.23 ? 171 PRO B O 1 ATOM 6107 C CB . PRO B 1 171 ? 10.703 33.602 21.562 1.00 65.22 ? 171 PRO B CB 1 ATOM 6108 C CG . PRO B 1 171 ? 10.960 32.112 21.687 1.00 65.20 ? 171 PRO B CG 1 ATOM 6109 C CD . PRO B 1 171 ? 11.912 31.882 22.824 1.00 64.46 ? 171 PRO B CD 1 ATOM 6110 N N . TYR B 1 172 ? 13.199 36.245 22.749 1.00 66.32 ? 172 TYR B N 1 ATOM 6111 C CA . TYR B 1 172 ? 13.861 37.606 23.040 1.00 66.16 ? 172 TYR B CA 1 ATOM 6112 C C . TYR B 1 172 ? 13.459 38.925 22.292 1.00 65.25 ? 172 TYR B C 1 ATOM 6113 O O . TYR B 1 172 ? 13.173 38.818 21.103 1.00 65.51 ? 172 TYR B O 1 ATOM 6114 C CB . TYR B 1 172 ? 15.301 37.411 22.624 1.00 68.86 ? 172 TYR B CB 1 ATOM 6115 C CG . TYR B 1 172 ? 15.481 36.649 21.322 1.00 71.15 ? 172 TYR B CG 1 ATOM 6116 C CD1 . TYR B 1 172 ? 15.072 35.296 21.211 1.00 71.95 ? 172 TYR B CD1 1 ATOM 6117 C CD2 . TYR B 1 172 ? 16.038 37.241 20.198 1.00 71.82 ? 172 TYR B CD2 1 ATOM 6118 C CE1 . TYR B 1 172 ? 15.270 34.574 20.028 1.00 72.94 ? 172 TYR B CE1 1 ATOM 6119 C CE2 . TYR B 1 172 ? 16.251 36.511 19.034 1.00 72.95 ? 172 TYR B CE2 1 ATOM 6120 C CZ . TYR B 1 172 ? 15.872 35.195 18.958 1.00 73.10 ? 172 TYR B CZ 1 ATOM 6121 O OH . TYR B 1 172 ? 16.096 34.504 17.798 1.00 73.49 ? 172 TYR B OH 1 ATOM 6122 N N . GLN B 1 173 ? 13.398 40.158 22.880 1.00 62.60 ? 173 GLN B N 1 ATOM 6123 C CA . GLN B 1 173 ? 12.895 41.323 22.049 1.00 59.52 ? 173 GLN B CA 1 ATOM 6124 C C . GLN B 1 173 ? 13.328 42.752 22.440 1.00 57.35 ? 173 GLN B C 1 ATOM 6125 O O . GLN B 1 173 ? 14.485 43.032 22.689 1.00 56.17 ? 173 GLN B O 1 ATOM 6126 C CB . GLN B 1 173 ? 11.362 41.261 22.042 1.00 59.33 ? 173 GLN B CB 1 ATOM 6127 C CG . GLN B 1 173 ? 10.708 41.745 23.325 1.00 59.45 ? 173 GLN B CG 1 ATOM 6128 C CD . GLN B 1 173 ? 9.279 41.245 23.416 1.00 60.01 ? 173 GLN B CD 1 ATOM 6129 O OE1 . GLN B 1 173 ? 8.352 41.917 22.970 1.00 59.89 ? 173 GLN B OE1 1 ATOM 6130 N NE2 . GLN B 1 173 ? 8.870 40.092 23.946 1.00 60.27 ? 173 GLN B NE2 1 ATOM 6131 N N . SER B 1 174 ? 12.312 43.626 22.466 1.00 54.88 ? 174 SER B N 1 ATOM 6132 C CA . SER B 1 174 ? 12.269 45.062 22.866 1.00 52.53 ? 174 SER B CA 1 ATOM 6133 C C . SER B 1 174 ? 13.410 46.113 22.948 1.00 50.20 ? 174 SER B C 1 ATOM 6134 O O . SER B 1 174 ? 13.569 46.907 22.010 1.00 50.86 ? 174 SER B O 1 ATOM 6135 C CB . SER B 1 174 ? 11.446 45.171 24.157 1.00 53.01 ? 174 SER B CB 1 ATOM 6136 O OG . SER B 1 174 ? 10.144 44.642 23.953 1.00 53.34 ? 174 SER B OG 1 ATOM 6137 N N . LEU B 1 175 ? 14.146 46.173 24.066 1.00 45.22 ? 175 LEU B N 1 ATOM 6138 C CA . LEU B 1 175 ? 15.229 47.161 24.240 1.00 39.16 ? 175 LEU B CA 1 ATOM 6139 C C . LEU B 1 175 ? 16.625 46.565 24.014 1.00 35.53 ? 175 LEU B C 1 ATOM 6140 O O . LEU B 1 175 ? 16.752 45.362 23.785 1.00 36.11 ? 175 LEU B O 1 ATOM 6141 C CB . LEU B 1 175 ? 15.164 47.779 25.640 1.00 38.39 ? 175 LEU B CB 1 ATOM 6142 C CG . LEU B 1 175 ? 15.778 49.179 25.756 1.00 38.05 ? 175 LEU B CG 1 ATOM 6143 C CD1 . LEU B 1 175 ? 14.651 50.169 26.018 1.00 37.95 ? 175 LEU B CD1 1 ATOM 6144 C CD2 . LEU B 1 175 ? 16.824 49.242 26.872 1.00 37.02 ? 175 LEU B CD2 1 ATOM 6145 N N . ALA B 1 176 ? 17.662 47.408 24.076 1.00 29.94 ? 176 ALA B N 1 ATOM 6146 C CA . ALA B 1 176 ? 19.057 46.977 23.875 1.00 23.85 ? 176 ALA B CA 1 ATOM 6147 C C . ALA B 1 176 ? 19.465 45.915 24.900 1.00 19.49 ? 176 ALA B C 1 ATOM 6148 O O . ALA B 1 176 ? 19.411 46.152 26.107 1.00 18.29 ? 176 ALA B O 1 ATOM 6149 C CB . ALA B 1 176 ? 19.990 48.181 23.964 1.00 24.51 ? 176 ALA B CB 1 ATOM 6150 N N . ARG B 1 177 ? 19.909 44.762 24.405 1.00 14.98 ? 177 ARG B N 1 ATOM 6151 C CA . ARG B 1 177 ? 20.268 43.626 25.257 1.00 11.86 ? 177 ARG B CA 1 ATOM 6152 C C . ARG B 1 177 ? 21.309 43.791 26.356 1.00 9.43 ? 177 ARG B C 1 ATOM 6153 O O . ARG B 1 177 ? 22.391 44.336 26.152 1.00 7.15 ? 177 ARG B O 1 ATOM 6154 C CB . ARG B 1 177 ? 20.673 42.432 24.392 1.00 12.14 ? 177 ARG B CB 1 ATOM 6155 C CG . ARG B 1 177 ? 20.655 41.110 25.145 1.00 10.59 ? 177 ARG B CG 1 ATOM 6156 C CD . ARG B 1 177 ? 19.674 40.152 24.508 1.00 10.18 ? 177 ARG B CD 1 ATOM 6157 N NE . ARG B 1 177 ? 20.333 39.147 23.684 1.00 11.11 ? 177 ARG B NE 1 ATOM 6158 C CZ . ARG B 1 177 ? 19.681 38.285 22.908 1.00 12.98 ? 177 ARG B CZ 1 ATOM 6159 N NH1 . ARG B 1 177 ? 18.353 38.323 22.855 1.00 13.45 ? 177 ARG B NH1 1 ATOM 6160 N NH2 . ARG B 1 177 ? 20.347 37.378 22.200 1.00 12.18 ? 177 ARG B NH2 1 ATOM 6161 N N . ASP B 1 178 ? 20.966 43.276 27.530 1.00 7.14 ? 178 ASP B N 1 ATOM 6162 C CA . ASP B 1 178 ? 21.852 43.336 28.675 1.00 6.90 ? 178 ASP B CA 1 ATOM 6163 C C . ASP B 1 178 ? 21.883 41.948 29.287 1.00 6.23 ? 178 ASP B C 1 ATOM 6164 O O . ASP B 1 178 ? 20.843 41.410 29.650 1.00 6.00 ? 178 ASP B O 1 ATOM 6165 C CB . ASP B 1 178 ? 21.350 44.380 29.687 1.00 7.96 ? 178 ASP B CB 1 ATOM 6166 C CG . ASP B 1 178 ? 21.518 45.817 29.180 1.00 9.78 ? 178 ASP B CG 1 ATOM 6167 O OD1 . ASP B 1 178 ? 22.664 46.188 28.822 1.00 8.49 ? 178 ASP B OD1 1 ATOM 6168 O OD2 . ASP B 1 178 ? 20.512 46.571 29.142 1.00 8.94 ? 178 ASP B OD2 1 ATOM 6169 N N . GLN B 1 179 ? 23.074 41.361 29.373 1.00 5.31 ? 179 GLN B N 1 ATOM 6170 C CA . GLN B 1 179 ? 23.227 40.025 29.931 1.00 4.02 ? 179 GLN B CA 1 ATOM 6171 C C . GLN B 1 179 ? 23.390 40.048 31.429 1.00 4.56 ? 179 GLN B C 1 ATOM 6172 O O . GLN B 1 179 ? 23.883 41.020 31.997 1.00 3.71 ? 179 GLN B O 1 ATOM 6173 C CB . GLN B 1 179 ? 24.416 39.307 29.311 1.00 4.60 ? 179 GLN B CB 1 ATOM 6174 C CG . GLN B 1 179 ? 25.404 40.226 28.652 1.00 6.13 ? 179 GLN B CG 1 ATOM 6175 C CD . GLN B 1 179 ? 25.045 40.528 27.214 1.00 5.37 ? 179 GLN B CD 1 ATOM 6176 O OE1 . GLN B 1 179 ? 24.619 39.642 26.472 1.00 5.76 ? 179 GLN B OE1 1 ATOM 6177 N NE2 . GLN B 1 179 ? 25.233 41.776 26.806 1.00 5.46 ? 179 GLN B NE2 1 ATOM 6178 N N . ILE B 1 180 ? 22.992 38.937 32.043 1.00 4.28 ? 180 ILE B N 1 ATOM 6179 C CA . ILE B 1 180 ? 23.003 38.741 33.488 1.00 3.20 ? 180 ILE B CA 1 ATOM 6180 C C . ILE B 1 180 ? 24.314 38.360 34.171 1.00 3.96 ? 180 ILE B C 1 ATOM 6181 O O . ILE B 1 180 ? 25.171 37.716 33.578 1.00 4.74 ? 180 ILE B O 1 ATOM 6182 C CB . ILE B 1 180 ? 21.969 37.665 33.867 1.00 3.76 ? 180 ILE B CB 1 ATOM 6183 C CG1 . ILE B 1 180 ? 20.558 38.173 33.587 1.00 4.69 ? 180 ILE B CG1 1 ATOM 6184 C CG2 . ILE B 1 180 ? 22.103 37.293 35.335 1.00 5.86 ? 180 ILE B CG2 1 ATOM 6185 C CD1 . ILE B 1 180 ? 19.467 37.195 34.027 1.00 5.45 ? 180 ILE B CD1 1 ATOM 6186 N N . ASN B 1 181 ? 24.431 38.769 35.436 1.00 3.52 ? 181 ASN B N 1 ATOM 6187 C CA . ASN B 1 181 ? 25.565 38.466 36.327 1.00 3.42 ? 181 ASN B CA 1 ATOM 6188 C C . ASN B 1 181 ? 24.908 37.618 37.448 1.00 2.00 ? 181 ASN B C 1 ATOM 6189 O O . ASN B 1 181 ? 24.235 38.155 38.326 1.00 2.00 ? 181 ASN B O 1 ATOM 6190 C CB . ASN B 1 181 ? 26.147 39.781 36.882 1.00 2.89 ? 181 ASN B CB 1 ATOM 6191 C CG . ASN B 1 181 ? 27.238 39.570 37.927 1.00 2.16 ? 181 ASN B CG 1 ATOM 6192 O OD1 . ASN B 1 181 ? 27.576 38.446 38.284 1.00 2.66 ? 181 ASN B OD1 1 ATOM 6193 N ND2 . ASN B 1 181 ? 27.786 40.670 38.425 1.00 2.50 ? 181 ASN B ND2 1 ATOM 6194 N N . SER B 1 182 ? 25.092 36.298 37.404 1.00 2.00 ? 182 SER B N 1 ATOM 6195 C CA . SER B 1 182 ? 24.426 35.405 38.374 1.00 3.55 ? 182 SER B CA 1 ATOM 6196 C C . SER B 1 182 ? 25.102 35.343 39.751 1.00 2.74 ? 182 SER B C 1 ATOM 6197 O O . SER B 1 182 ? 24.690 34.584 40.619 1.00 2.00 ? 182 SER B O 1 ATOM 6198 C CB . SER B 1 182 ? 24.340 33.988 37.790 1.00 5.07 ? 182 SER B CB 1 ATOM 6199 O OG . SER B 1 182 ? 25.598 33.343 37.825 1.00 7.37 ? 182 SER B OG 1 ATOM 6200 N N . VAL B 1 183 ? 26.145 36.172 39.947 1.00 2.00 ? 183 VAL B N 1 ATOM 6201 C CA . VAL B 1 183 ? 26.895 36.269 41.196 1.00 2.73 ? 183 VAL B CA 1 ATOM 6202 C C . VAL B 1 183 ? 26.906 37.724 41.705 1.00 4.17 ? 183 VAL B C 1 ATOM 6203 O O . VAL B 1 183 ? 26.392 38.625 41.044 1.00 4.79 ? 183 VAL B O 1 ATOM 6204 C CB . VAL B 1 183 ? 28.332 35.805 41.077 1.00 2.00 ? 183 VAL B CB 1 ATOM 6205 C CG1 . VAL B 1 183 ? 28.404 34.310 40.844 1.00 2.40 ? 183 VAL B CG1 1 ATOM 6206 C CG2 . VAL B 1 183 ? 29.032 36.548 39.959 1.00 2.14 ? 183 VAL B CG2 1 ATOM 6207 N N . THR B 1 184 ? 27.526 37.955 42.865 1.00 3.00 ? 184 THR B N 1 ATOM 6208 C CA . THR B 1 184 ? 27.498 39.269 43.494 1.00 2.85 ? 184 THR B CA 1 ATOM 6209 C C . THR B 1 184 ? 28.746 40.079 43.327 1.00 2.78 ? 184 THR B C 1 ATOM 6210 O O . THR B 1 184 ? 29.869 39.598 43.457 1.00 2.08 ? 184 THR B O 1 ATOM 6211 C CB . THR B 1 184 ? 27.147 39.148 44.956 1.00 3.09 ? 184 THR B CB 1 ATOM 6212 O OG1 . THR B 1 184 ? 28.299 38.774 45.717 1.00 2.00 ? 184 THR B OG1 1 ATOM 6213 C CG2 . THR B 1 184 ? 26.062 38.096 45.149 1.00 3.18 ? 184 THR B CG2 1 ATOM 6214 N N . SER B 1 185 ? 28.459 41.343 43.026 1.00 3.47 ? 185 SER B N 1 ATOM 6215 C CA . SER B 1 185 ? 29.543 42.240 42.746 1.00 4.56 ? 185 SER B CA 1 ATOM 6216 C C . SER B 1 185 ? 30.458 42.528 43.924 1.00 3.49 ? 185 SER B C 1 ATOM 6217 O O . SER B 1 185 ? 31.418 43.293 43.785 1.00 4.64 ? 185 SER B O 1 ATOM 6218 C CB . SER B 1 185 ? 28.960 43.558 42.218 1.00 6.10 ? 185 SER B CB 1 ATOM 6219 O OG . SER B 1 185 ? 27.680 43.348 41.634 1.00 10.68 ? 185 SER B OG 1 ATOM 6220 N N . PHE B 1 186 ? 30.227 41.956 45.074 1.00 3.52 ? 186 PHE B N 1 ATOM 6221 C CA . PHE B 1 186 ? 31.083 42.290 46.209 1.00 2.16 ? 186 PHE B CA 1 ATOM 6222 C C . PHE B 1 186 ? 32.153 41.239 46.526 1.00 2.18 ? 186 PHE B C 1 ATOM 6223 O O . PHE B 1 186 ? 31.901 40.022 46.428 1.00 3.03 ? 186 PHE B O 1 ATOM 6224 C CB . PHE B 1 186 ? 30.200 42.452 47.474 1.00 2.00 ? 186 PHE B CB 1 ATOM 6225 C CG . PHE B 1 186 ? 29.059 43.408 47.323 1.00 2.00 ? 186 PHE B CG 1 ATOM 6226 C CD1 . PHE B 1 186 ? 29.303 44.763 47.505 1.00 2.00 ? 186 PHE B CD1 1 ATOM 6227 C CD2 . PHE B 1 186 ? 27.763 43.007 47.022 1.00 2.00 ? 186 PHE B CD2 1 ATOM 6228 C CE1 . PHE B 1 186 ? 28.269 45.697 47.386 1.00 2.00 ? 186 PHE B CE1 1 ATOM 6229 C CE2 . PHE B 1 186 ? 26.730 43.937 46.903 1.00 2.00 ? 186 PHE B CE2 1 ATOM 6230 C CZ . PHE B 1 186 ? 26.985 45.278 47.085 1.00 2.00 ? 186 PHE B CZ 1 ATOM 6231 N N . LEU B 1 187 ? 33.343 41.706 46.918 1.00 2.03 ? 187 LEU B N 1 ATOM 6232 C CA . LEU B 1 187 ? 34.362 40.731 47.303 1.00 2.00 ? 187 LEU B CA 1 ATOM 6233 C C . LEU B 1 187 ? 33.876 40.094 48.609 1.00 2.00 ? 187 LEU B C 1 ATOM 6234 O O . LEU B 1 187 ? 34.468 40.309 49.657 1.00 2.05 ? 187 LEU B O 1 ATOM 6235 C CB . LEU B 1 187 ? 35.695 41.413 47.561 1.00 2.00 ? 187 LEU B CB 1 ATOM 6236 C CG . LEU B 1 187 ? 36.779 40.938 46.616 1.00 2.00 ? 187 LEU B CG 1 ATOM 6237 C CD1 . LEU B 1 187 ? 38.153 41.369 47.124 1.00 2.00 ? 187 LEU B CD1 1 ATOM 6238 C CD2 . LEU B 1 187 ? 36.686 39.427 46.510 1.00 2.00 ? 187 LEU B CD2 1 ATOM 6239 N N . ASP B 1 188 ? 32.807 39.310 48.557 1.00 2.00 ? 188 ASP B N 1 ATOM 6240 C CA . ASP B 1 188 ? 32.246 38.716 49.773 1.00 2.00 ? 188 ASP B CA 1 ATOM 6241 C C . ASP B 1 188 ? 32.357 37.200 49.835 1.00 2.07 ? 188 ASP B C 1 ATOM 6242 O O . ASP B 1 188 ? 31.512 36.532 50.447 1.00 2.31 ? 188 ASP B O 1 ATOM 6243 C CB . ASP B 1 188 ? 30.780 39.084 49.849 1.00 3.08 ? 188 ASP B CB 1 ATOM 6244 C CG . ASP B 1 188 ? 30.052 38.670 48.607 1.00 4.11 ? 188 ASP B CG 1 ATOM 6245 O OD1 . ASP B 1 188 ? 30.745 38.079 47.751 1.00 3.51 ? 188 ASP B OD1 1 ATOM 6246 O OD2 . ASP B 1 188 ? 28.835 38.919 48.476 1.00 4.12 ? 188 ASP B OD2 1 ATOM 6247 N N . ALA B 1 189 ? 33.374 36.657 49.182 1.00 2.53 ? 189 ALA B N 1 ATOM 6248 C CA . ALA B 1 189 ? 33.598 35.217 49.186 1.00 2.00 ? 189 ALA B CA 1 ATOM 6249 C C . ALA B 1 189 ? 32.328 34.467 48.861 1.00 2.00 ? 189 ALA B C 1 ATOM 6250 O O . ALA B 1 189 ? 32.005 33.460 49.475 1.00 2.45 ? 189 ALA B O 1 ATOM 6251 C CB . ALA B 1 189 ? 34.114 34.791 50.533 1.00 2.00 ? 189 ALA B CB 1 ATOM 6252 N N . SER B 1 190 ? 31.591 34.978 47.894 1.00 2.17 ? 190 SER B N 1 ATOM 6253 C CA . SER B 1 190 ? 30.362 34.329 47.508 1.00 3.12 ? 190 SER B CA 1 ATOM 6254 C C . SER B 1 190 ? 30.702 33.110 46.638 1.00 2.60 ? 190 SER B C 1 ATOM 6255 O O . SER B 1 190 ? 29.814 32.499 46.042 1.00 3.74 ? 190 SER B O 1 ATOM 6256 C CB . SER B 1 190 ? 29.500 35.302 46.722 1.00 3.54 ? 190 SER B CB 1 ATOM 6257 O OG . SER B 1 190 ? 30.066 35.541 45.445 1.00 5.10 ? 190 SER B OG 1 ATOM 6258 N N . LEU B 1 191 ? 31.980 32.763 46.529 1.00 2.58 ? 191 LEU B N 1 ATOM 6259 C CA . LEU B 1 191 ? 32.341 31.595 45.724 1.00 3.85 ? 191 LEU B CA 1 ATOM 6260 C C . LEU B 1 191 ? 32.448 30.433 46.685 1.00 5.45 ? 191 LEU B C 1 ATOM 6261 O O . LEU B 1 191 ? 32.410 29.262 46.287 1.00 7.96 ? 191 LEU B O 1 ATOM 6262 C CB . LEU B 1 191 ? 33.685 31.790 45.008 1.00 2.67 ? 191 LEU B CB 1 ATOM 6263 C CG . LEU B 1 191 ? 35.018 31.938 45.747 1.00 2.15 ? 191 LEU B CG 1 ATOM 6264 C CD1 . LEU B 1 191 ? 36.112 32.199 44.713 1.00 3.58 ? 191 LEU B CD1 1 ATOM 6265 C CD2 . LEU B 1 191 ? 34.950 33.093 46.729 1.00 2.00 ? 191 LEU B CD2 1 ATOM 6266 N N . VAL B 1 192 ? 32.578 30.784 47.960 1.00 3.68 ? 192 VAL B N 1 ATOM 6267 C CA . VAL B 1 192 ? 32.709 29.818 49.022 1.00 2.00 ? 192 VAL B CA 1 ATOM 6268 C C . VAL B 1 192 ? 31.361 29.526 49.642 1.00 2.21 ? 192 VAL B C 1 ATOM 6269 O O . VAL B 1 192 ? 31.141 28.427 50.127 1.00 4.01 ? 192 VAL B O 1 ATOM 6270 C CB . VAL B 1 192 ? 33.641 30.348 50.112 1.00 2.00 ? 192 VAL B CB 1 ATOM 6271 C CG1 . VAL B 1 192 ? 33.484 29.525 51.368 1.00 2.00 ? 192 VAL B CG1 1 ATOM 6272 C CG2 . VAL B 1 192 ? 35.082 30.317 49.626 1.00 2.44 ? 192 VAL B CG2 1 ATOM 6273 N N . TYR B 1 193 ? 30.456 30.499 49.621 1.00 2.54 ? 193 TYR B N 1 ATOM 6274 C CA . TYR B 1 193 ? 29.138 30.317 50.235 1.00 2.00 ? 193 TYR B CA 1 ATOM 6275 C C . TYR B 1 193 ? 27.936 30.290 49.290 1.00 2.14 ? 193 TYR B C 1 ATOM 6276 O O . TYR B 1 193 ? 26.850 29.860 49.679 1.00 2.00 ? 193 TYR B O 1 ATOM 6277 C CB . TYR B 1 193 ? 28.927 31.396 51.290 1.00 2.00 ? 193 TYR B CB 1 ATOM 6278 C CG . TYR B 1 193 ? 30.004 31.395 52.336 1.00 2.00 ? 193 TYR B CG 1 ATOM 6279 C CD1 . TYR B 1 193 ? 30.056 30.396 53.303 1.00 2.00 ? 193 TYR B CD1 1 ATOM 6280 C CD2 . TYR B 1 193 ? 31.000 32.366 52.334 1.00 2.00 ? 193 TYR B CD2 1 ATOM 6281 C CE1 . TYR B 1 193 ? 31.078 30.363 54.242 1.00 2.05 ? 193 TYR B CE1 1 ATOM 6282 C CE2 . TYR B 1 193 ? 32.027 32.342 53.269 1.00 2.00 ? 193 TYR B CE2 1 ATOM 6283 C CZ . TYR B 1 193 ? 32.058 31.340 54.218 1.00 2.00 ? 193 TYR B CZ 1 ATOM 6284 O OH . TYR B 1 193 ? 33.062 31.318 55.150 1.00 2.00 ? 193 TYR B OH 1 ATOM 6285 N N . GLY B 1 194 ? 28.124 30.773 48.064 1.00 3.29 ? 194 GLY B N 1 ATOM 6286 C CA . GLY B 1 194 ? 27.048 30.770 47.084 1.00 4.48 ? 194 GLY B CA 1 ATOM 6287 C C . GLY B 1 194 ? 26.338 32.094 46.867 1.00 5.66 ? 194 GLY B C 1 ATOM 6288 O O . GLY B 1 194 ? 26.606 33.069 47.579 1.00 5.48 ? 194 GLY B O 1 ATOM 6289 N N . SER B 1 195 ? 25.432 32.127 45.883 1.00 6.80 ? 195 SER B N 1 ATOM 6290 C CA . SER B 1 195 ? 24.666 33.333 45.569 1.00 7.74 ? 195 SER B CA 1 ATOM 6291 C C . SER B 1 195 ? 23.139 33.190 45.633 1.00 9.84 ? 195 SER B C 1 ATOM 6292 O O . SER B 1 195 ? 22.422 34.187 45.517 1.00 11.41 ? 195 SER B O 1 ATOM 6293 C CB . SER B 1 195 ? 25.080 33.889 44.206 1.00 7.43 ? 195 SER B CB 1 ATOM 6294 O OG . SER B 1 195 ? 26.382 34.451 44.269 1.00 6.82 ? 195 SER B OG 1 ATOM 6295 N N . GLU B 1 196 ? 22.638 31.966 45.798 1.00 11.57 ? 196 GLU B N 1 ATOM 6296 C CA . GLU B 1 196 ? 21.193 31.745 45.944 1.00 13.38 ? 196 GLU B CA 1 ATOM 6297 C C . GLU B 1 196 ? 20.947 30.885 47.189 1.00 13.02 ? 196 GLU B C 1 ATOM 6298 O O . GLU B 1 196 ? 21.333 29.714 47.231 1.00 13.04 ? 196 GLU B O 1 ATOM 6299 C CB . GLU B 1 196 ? 20.588 31.070 44.711 1.00 15.94 ? 196 GLU B CB 1 ATOM 6300 C CG . GLU B 1 196 ? 21.298 29.818 44.251 1.00 20.63 ? 196 GLU B CG 1 ATOM 6301 C CD . GLU B 1 196 ? 20.394 28.920 43.427 1.00 22.44 ? 196 GLU B CD 1 ATOM 6302 O OE1 . GLU B 1 196 ? 19.477 28.321 44.029 1.00 23.54 ? 196 GLU B OE1 1 ATOM 6303 O OE2 . GLU B 1 196 ? 20.593 28.818 42.189 1.00 22.56 ? 196 GLU B OE2 1 ATOM 6304 N N . PRO B 1 197 ? 20.290 31.461 48.216 1.00 11.41 ? 197 PRO B N 1 ATOM 6305 C CA . PRO B 1 197 ? 19.958 30.825 49.502 1.00 9.54 ? 197 PRO B CA 1 ATOM 6306 C C . PRO B 1 197 ? 19.717 29.326 49.376 1.00 9.70 ? 197 PRO B C 1 ATOM 6307 O O . PRO B 1 197 ? 20.160 28.526 50.195 1.00 8.29 ? 197 PRO B O 1 ATOM 6308 C CB . PRO B 1 197 ? 18.703 31.567 49.932 1.00 10.61 ? 197 PRO B CB 1 ATOM 6309 C CG . PRO B 1 197 ? 18.938 32.929 49.406 1.00 11.51 ? 197 PRO B CG 1 ATOM 6310 C CD . PRO B 1 197 ? 19.477 32.674 48.020 1.00 10.50 ? 197 PRO B CD 1 ATOM 6311 N N . SER B 1 198 ? 18.986 28.969 48.338 1.00 10.10 ? 198 SER B N 1 ATOM 6312 C CA . SER B 1 198 ? 18.681 27.592 48.043 1.00 10.29 ? 198 SER B CA 1 ATOM 6313 C C . SER B 1 198 ? 19.963 26.765 48.189 1.00 12.77 ? 198 SER B C 1 ATOM 6314 O O . SER B 1 198 ? 20.023 25.801 48.963 1.00 12.52 ? 198 SER B O 1 ATOM 6315 C CB . SER B 1 198 ? 18.163 27.532 46.609 1.00 12.45 ? 198 SER B CB 1 ATOM 6316 O OG . SER B 1 198 ? 18.156 28.845 46.043 1.00 13.63 ? 198 SER B OG 1 ATOM 6317 N N . LEU B 1 199 ? 21.000 27.164 47.458 1.00 12.71 ? 199 LEU B N 1 ATOM 6318 C CA . LEU B 1 199 ? 22.264 26.444 47.486 1.00 12.02 ? 199 LEU B CA 1 ATOM 6319 C C . LEU B 1 199 ? 23.176 26.746 48.661 1.00 11.08 ? 199 LEU B C 1 ATOM 6320 O O . LEU B 1 199 ? 24.059 25.950 48.973 1.00 12.20 ? 199 LEU B O 1 ATOM 6321 C CB . LEU B 1 199 ? 23.040 26.693 46.197 1.00 12.53 ? 199 LEU B CB 1 ATOM 6322 C CG . LEU B 1 199 ? 24.438 26.064 46.157 1.00 13.11 ? 199 LEU B CG 1 ATOM 6323 C CD1 . LEU B 1 199 ? 24.353 24.536 46.271 1.00 13.05 ? 199 LEU B CD1 1 ATOM 6324 C CD2 . LEU B 1 199 ? 25.118 26.467 44.861 1.00 14.12 ? 199 LEU B CD2 1 ATOM 6325 N N . ALA B 1 200 ? 22.982 27.885 49.312 1.00 10.09 ? 200 ALA B N 1 ATOM 6326 C CA . ALA B 1 200 ? 23.842 28.238 50.435 1.00 9.57 ? 200 ALA B CA 1 ATOM 6327 C C . ALA B 1 200 ? 23.611 27.341 51.637 1.00 9.78 ? 200 ALA B C 1 ATOM 6328 O O . ALA B 1 200 ? 24.464 27.259 52.524 1.00 10.73 ? 200 ALA B O 1 ATOM 6329 C CB . ALA B 1 200 ? 23.638 29.687 50.825 1.00 10.22 ? 200 ALA B CB 1 ATOM 6330 N N . SER B 1 201 ? 22.463 26.671 51.678 1.00 9.31 ? 201 SER B N 1 ATOM 6331 C CA . SER B 1 201 ? 22.185 25.787 52.800 1.00 9.83 ? 201 SER B CA 1 ATOM 6332 C C . SER B 1 201 ? 22.626 24.368 52.448 1.00 11.26 ? 201 SER B C 1 ATOM 6333 O O . SER B 1 201 ? 23.025 23.601 53.331 1.00 11.57 ? 201 SER B O 1 ATOM 6334 C CB . SER B 1 201 ? 20.697 25.823 53.174 1.00 7.92 ? 201 SER B CB 1 ATOM 6335 O OG . SER B 1 201 ? 19.976 24.769 52.570 1.00 9.37 ? 201 SER B OG 1 ATOM 6336 N N . ARG B 1 202 ? 22.568 24.016 51.163 1.00 10.71 ? 202 ARG B N 1 ATOM 6337 C CA . ARG B 1 202 ? 23.003 22.684 50.745 1.00 11.71 ? 202 ARG B CA 1 ATOM 6338 C C . ARG B 1 202 ? 24.459 22.509 51.151 1.00 10.20 ? 202 ARG B C 1 ATOM 6339 O O . ARG B 1 202 ? 24.910 21.396 51.449 1.00 9.22 ? 202 ARG B O 1 ATOM 6340 C CB . ARG B 1 202 ? 22.893 22.516 49.226 1.00 16.73 ? 202 ARG B CB 1 ATOM 6341 C CG . ARG B 1 202 ? 21.508 22.173 48.689 1.00 24.79 ? 202 ARG B CG 1 ATOM 6342 C CD . ARG B 1 202 ? 21.505 22.123 47.153 1.00 29.30 ? 202 ARG B CD 1 ATOM 6343 N NE . ARG B 1 202 ? 22.556 21.254 46.620 1.00 35.40 ? 202 ARG B NE 1 ATOM 6344 C CZ . ARG B 1 202 ? 22.621 19.938 46.823 1.00 37.80 ? 202 ARG B CZ 1 ATOM 6345 N NH1 . ARG B 1 202 ? 21.689 19.331 47.550 1.00 39.18 ? 202 ARG B NH1 1 ATOM 6346 N NH2 . ARG B 1 202 ? 23.614 19.223 46.297 1.00 39.09 ? 202 ARG B NH2 1 ATOM 6347 N N . LEU B 1 203 ? 25.184 23.635 51.158 1.00 7.91 ? 203 LEU B N 1 ATOM 6348 C CA . LEU B 1 203 ? 26.611 23.581 51.456 1.00 6.89 ? 203 LEU B CA 1 ATOM 6349 C C . LEU B 1 203 ? 26.929 23.347 52.950 1.00 7.89 ? 203 LEU B C 1 ATOM 6350 O O . LEU B 1 203 ? 28.087 23.253 53.342 1.00 8.59 ? 203 LEU B O 1 ATOM 6351 C CB . LEU B 1 203 ? 27.287 24.885 50.892 1.00 5.96 ? 203 LEU B CB 1 ATOM 6352 C CG . LEU B 1 203 ? 27.789 24.941 49.411 1.00 5.94 ? 203 LEU B CG 1 ATOM 6353 C CD1 . LEU B 1 203 ? 26.826 24.207 48.496 1.00 4.68 ? 203 LEU B CD1 1 ATOM 6354 C CD2 . LEU B 1 203 ? 27.952 26.390 48.966 1.00 3.69 ? 203 LEU B CD2 1 ATOM 6355 N N . ARG B 1 204 ? 25.884 23.253 53.754 1.00 8.67 ? 204 ARG B N 1 ATOM 6356 C CA . ARG B 1 204 ? 26.056 23.287 55.221 1.00 8.35 ? 204 ARG B CA 1 ATOM 6357 C C . ARG B 1 204 ? 25.873 22.042 56.099 1.00 8.36 ? 204 ARG B C 1 ATOM 6358 O O . ARG B 1 204 ? 24.861 21.341 55.998 1.00 9.12 ? 204 ARG B O 1 ATOM 6359 C CB . ARG B 1 204 ? 25.072 24.340 55.707 1.00 6.55 ? 204 ARG B CB 1 ATOM 6360 C CG . ARG B 1 204 ? 25.640 25.437 56.572 1.00 6.47 ? 204 ARG B CG 1 ATOM 6361 C CD . ARG B 1 204 ? 24.658 26.576 56.592 1.00 4.07 ? 204 ARG B CD 1 ATOM 6362 N NE . ARG B 1 204 ? 24.667 27.299 57.849 1.00 2.53 ? 204 ARG B NE 1 ATOM 6363 C CZ . ARG B 1 204 ? 23.764 28.207 58.186 1.00 2.73 ? 204 ARG B CZ 1 ATOM 6364 N NH1 . ARG B 1 204 ? 22.774 28.506 57.356 1.00 4.78 ? 204 ARG B NH1 1 ATOM 6365 N NH2 . ARG B 1 204 ? 23.848 28.813 59.358 1.00 3.66 ? 204 ARG B NH2 1 ATOM 6366 N N . ASN B 1 205 ? 26.882 21.774 56.938 1.00 8.14 ? 205 ASN B N 1 ATOM 6367 C CA . ASN B 1 205 ? 26.755 20.766 57.954 1.00 8.77 ? 205 ASN B CA 1 ATOM 6368 C C . ASN B 1 205 ? 25.699 21.432 58.847 1.00 9.55 ? 205 ASN B C 1 ATOM 6369 O O . ASN B 1 205 ? 26.044 22.309 59.654 1.00 11.01 ? 205 ASN B O 1 ATOM 6370 C CB . ASN B 1 205 ? 28.098 20.498 58.688 1.00 11.28 ? 205 ASN B CB 1 ATOM 6371 C CG . ASN B 1 205 ? 28.143 19.240 59.499 1.00 15.60 ? 205 ASN B CG 1 ATOM 6372 O OD1 . ASN B 1 205 ? 27.120 18.855 60.072 1.00 12.67 ? 205 ASN B OD1 1 ATOM 6373 N ND2 . ASN B 1 205 ? 29.295 18.594 59.567 1.00 22.08 ? 205 ASN B ND2 1 ATOM 6374 N N . LEU B 1 206 ? 24.415 21.044 58.721 1.00 7.78 ? 206 LEU B N 1 ATOM 6375 C CA . LEU B 1 206 ? 23.378 21.645 59.577 1.00 5.28 ? 206 LEU B CA 1 ATOM 6376 C C . LEU B 1 206 ? 22.728 20.626 60.492 1.00 7.30 ? 206 LEU B C 1 ATOM 6377 O O . LEU B 1 206 ? 21.527 20.705 60.789 1.00 8.31 ? 206 LEU B O 1 ATOM 6378 C CB . LEU B 1 206 ? 22.251 22.250 58.734 1.00 4.26 ? 206 LEU B CB 1 ATOM 6379 C CG . LEU B 1 206 ? 22.484 23.556 57.981 1.00 3.79 ? 206 LEU B CG 1 ATOM 6380 C CD1 . LEU B 1 206 ? 21.269 23.910 57.151 1.00 2.00 ? 206 LEU B CD1 1 ATOM 6381 C CD2 . LEU B 1 206 ? 22.832 24.679 58.948 1.00 2.43 ? 206 LEU B CD2 1 ATOM 6382 N N . SER B 1 207 ? 23.517 19.643 60.931 1.00 6.59 ? 207 SER B N 1 ATOM 6383 C CA . SER B 1 207 ? 23.056 18.597 61.841 1.00 4.55 ? 207 SER B CA 1 ATOM 6384 C C . SER B 1 207 ? 23.890 18.694 63.107 1.00 5.78 ? 207 SER B C 1 ATOM 6385 O O . SER B 1 207 ? 23.538 18.159 64.154 1.00 7.53 ? 207 SER B O 1 ATOM 6386 C CB . SER B 1 207 ? 23.205 17.235 61.186 1.00 2.45 ? 207 SER B CB 1 ATOM 6387 O OG . SER B 1 207 ? 24.274 17.269 60.269 1.00 2.00 ? 207 SER B OG 1 ATOM 6388 N N . SER B 1 208 ? 25.017 19.377 62.997 1.00 6.49 ? 208 SER B N 1 ATOM 6389 C CA . SER B 1 208 ? 25.866 19.607 64.152 1.00 8.62 ? 208 SER B CA 1 ATOM 6390 C C . SER B 1 208 ? 25.532 21.063 64.458 1.00 10.25 ? 208 SER B C 1 ATOM 6391 O O . SER B 1 208 ? 25.528 21.895 63.551 1.00 12.39 ? 208 SER B O 1 ATOM 6392 C CB . SER B 1 208 ? 27.347 19.454 63.776 1.00 8.25 ? 208 SER B CB 1 ATOM 6393 O OG . SER B 1 208 ? 27.697 20.274 62.666 1.00 8.76 ? 208 SER B OG 1 ATOM 6394 N N . PRO B 1 209 ? 25.206 21.393 65.718 1.00 9.47 ? 209 PRO B N 1 ATOM 6395 C CA . PRO B 1 209 ? 24.887 22.797 65.994 1.00 9.50 ? 209 PRO B CA 1 ATOM 6396 C C . PRO B 1 209 ? 26.134 23.630 66.273 1.00 8.08 ? 209 PRO B C 1 ATOM 6397 O O . PRO B 1 209 ? 26.240 24.263 67.320 1.00 7.20 ? 209 PRO B O 1 ATOM 6398 C CB . PRO B 1 209 ? 23.967 22.703 67.204 1.00 8.43 ? 209 PRO B CB 1 ATOM 6399 C CG . PRO B 1 209 ? 24.596 21.610 67.973 1.00 11.28 ? 209 PRO B CG 1 ATOM 6400 C CD . PRO B 1 209 ? 24.930 20.558 66.899 1.00 11.09 ? 209 PRO B CD 1 ATOM 6401 N N . LEU B 1 210 ? 27.069 23.629 65.328 1.00 7.99 ? 210 LEU B N 1 ATOM 6402 C CA . LEU B 1 210 ? 28.306 24.378 65.488 1.00 9.48 ? 210 LEU B CA 1 ATOM 6403 C C . LEU B 1 210 ? 28.808 25.029 64.182 1.00 9.99 ? 210 LEU B C 1 ATOM 6404 O O . LEU B 1 210 ? 30.019 25.080 63.925 1.00 9.54 ? 210 LEU B O 1 ATOM 6405 C CB . LEU B 1 210 ? 29.376 23.457 66.082 1.00 10.83 ? 210 LEU B CB 1 ATOM 6406 C CG . LEU B 1 210 ? 29.661 22.159 65.324 1.00 12.66 ? 210 LEU B CG 1 ATOM 6407 C CD1 . LEU B 1 210 ? 31.146 22.098 65.029 1.00 14.26 ? 210 LEU B CD1 1 ATOM 6408 C CD2 . LEU B 1 210 ? 29.227 20.941 66.131 1.00 13.00 ? 210 LEU B CD2 1 ATOM 6409 N N . GLY B 1 211 ? 27.855 25.525 63.382 1.00 9.85 ? 211 GLY B N 1 ATOM 6410 C CA . GLY B 1 211 ? 28.124 26.197 62.111 1.00 7.23 ? 211 GLY B CA 1 ATOM 6411 C C . GLY B 1 211 ? 29.305 25.737 61.273 1.00 6.33 ? 211 GLY B C 1 ATOM 6412 O O . GLY B 1 211 ? 30.397 26.262 61.418 1.00 6.40 ? 211 GLY B O 1 ATOM 6413 N N . LEU B 1 212 ? 29.100 24.777 60.379 1.00 5.90 ? 212 LEU B N 1 ATOM 6414 C CA . LEU B 1 212 ? 30.201 24.280 59.554 1.00 5.39 ? 212 LEU B CA 1 ATOM 6415 C C . LEU B 1 212 ? 29.777 24.083 58.111 1.00 5.45 ? 212 LEU B C 1 ATOM 6416 O O . LEU B 1 212 ? 28.583 23.951 57.808 1.00 6.90 ? 212 LEU B O 1 ATOM 6417 C CB . LEU B 1 212 ? 30.719 22.932 60.074 1.00 3.44 ? 212 LEU B CB 1 ATOM 6418 C CG . LEU B 1 212 ? 31.560 22.735 61.334 1.00 2.00 ? 212 LEU B CG 1 ATOM 6419 C CD1 . LEU B 1 212 ? 31.863 21.252 61.458 1.00 2.57 ? 212 LEU B CD1 1 ATOM 6420 C CD2 . LEU B 1 212 ? 32.860 23.503 61.255 1.00 2.00 ? 212 LEU B CD2 1 ATOM 6421 N N . MET B 1 213 ? 30.762 24.045 57.221 1.00 4.09 ? 213 MET B N 1 ATOM 6422 C CA . MET B 1 213 ? 30.478 23.837 55.814 1.00 3.75 ? 213 MET B CA 1 ATOM 6423 C C . MET B 1 213 ? 30.397 22.346 55.557 1.00 3.08 ? 213 MET B C 1 ATOM 6424 O O . MET B 1 213 ? 31.144 21.557 56.141 1.00 2.24 ? 213 MET B O 1 ATOM 6425 C CB . MET B 1 213 ? 31.574 24.443 54.941 1.00 2.77 ? 213 MET B CB 1 ATOM 6426 C CG . MET B 1 213 ? 31.599 25.944 54.947 1.00 2.00 ? 213 MET B CG 1 ATOM 6427 S SD . MET B 1 213 ? 29.985 26.551 54.544 1.00 2.00 ? 213 MET B SD 1 ATOM 6428 C CE . MET B 1 213 ? 29.950 26.268 52.801 1.00 2.45 ? 213 MET B CE 1 ATOM 6429 N N . ALA B 1 214 ? 29.478 21.957 54.691 1.00 2.00 ? 214 ALA B N 1 ATOM 6430 C CA . ALA B 1 214 ? 29.345 20.554 54.375 1.00 2.03 ? 214 ALA B CA 1 ATOM 6431 C C . ALA B 1 214 ? 30.657 20.104 53.735 1.00 2.00 ? 214 ALA B C 1 ATOM 6432 O O . ALA B 1 214 ? 31.227 20.844 52.940 1.00 2.31 ? 214 ALA B O 1 ATOM 6433 C CB . ALA B 1 214 ? 28.188 20.361 53.411 1.00 2.00 ? 214 ALA B CB 1 ATOM 6434 N N . VAL B 1 215 ? 31.148 18.917 54.094 1.00 2.00 ? 215 VAL B N 1 ATOM 6435 C CA . VAL B 1 215 ? 32.382 18.389 53.499 1.00 2.53 ? 215 VAL B CA 1 ATOM 6436 C C . VAL B 1 215 ? 32.231 16.927 53.032 1.00 4.11 ? 215 VAL B C 1 ATOM 6437 O O . VAL B 1 215 ? 31.271 16.238 53.385 1.00 4.19 ? 215 VAL B O 1 ATOM 6438 C CB . VAL B 1 215 ? 33.566 18.488 54.475 1.00 2.00 ? 215 VAL B CB 1 ATOM 6439 C CG1 . VAL B 1 215 ? 33.387 19.694 55.355 1.00 2.00 ? 215 VAL B CG1 1 ATOM 6440 C CG2 . VAL B 1 215 ? 33.696 17.219 55.287 1.00 2.83 ? 215 VAL B CG2 1 ATOM 6441 N N . ASN B 1 216 ? 33.177 16.453 52.232 1.00 4.18 ? 216 ASN B N 1 ATOM 6442 C CA . ASN B 1 216 ? 33.109 15.088 51.727 1.00 4.97 ? 216 ASN B CA 1 ATOM 6443 C C . ASN B 1 216 ? 33.253 14.070 52.860 1.00 7.12 ? 216 ASN B C 1 ATOM 6444 O O . ASN B 1 216 ? 34.083 14.232 53.762 1.00 4.94 ? 216 ASN B O 1 ATOM 6445 C CB . ASN B 1 216 ? 34.209 14.859 50.683 1.00 4.82 ? 216 ASN B CB 1 ATOM 6446 C CG . ASN B 1 216 ? 33.849 13.784 49.673 1.00 5.15 ? 216 ASN B CG 1 ATOM 6447 O OD1 . ASN B 1 216 ? 34.665 13.414 48.827 1.00 4.95 ? 216 ASN B OD1 1 ATOM 6448 N ND2 . ASN B 1 216 ? 32.621 13.285 49.749 1.00 5.70 ? 216 ASN B ND2 1 ATOM 6449 N N . GLN B 1 217 ? 32.421 13.031 52.808 1.00 10.03 ? 217 GLN B N 1 ATOM 6450 C CA . GLN B 1 217 ? 32.444 11.951 53.788 1.00 12.49 ? 217 GLN B CA 1 ATOM 6451 C C . GLN B 1 217 ? 33.081 10.704 53.174 1.00 13.11 ? 217 GLN B C 1 ATOM 6452 O O . GLN B 1 217 ? 33.333 9.732 53.878 1.00 13.96 ? 217 GLN B O 1 ATOM 6453 C CB . GLN B 1 217 ? 31.024 11.596 54.250 1.00 16.58 ? 217 GLN B CB 1 ATOM 6454 C CG . GLN B 1 217 ? 30.406 12.530 55.284 1.00 23.00 ? 217 GLN B CG 1 ATOM 6455 C CD . GLN B 1 217 ? 31.280 12.700 56.516 1.00 26.75 ? 217 GLN B CD 1 ATOM 6456 O OE1 . GLN B 1 217 ? 31.783 13.794 56.784 1.00 30.09 ? 217 GLN B OE1 1 ATOM 6457 N NE2 . GLN B 1 217 ? 31.471 11.618 57.271 1.00 29.09 ? 217 GLN B NE2 1 ATOM 6458 N N . GLU B 1 218 ? 33.346 10.736 51.867 1.00 13.62 ? 218 GLU B N 1 ATOM 6459 C CA . GLU B 1 218 ? 33.934 9.594 51.159 1.00 12.81 ? 218 GLU B CA 1 ATOM 6460 C C . GLU B 1 218 ? 35.369 9.754 50.669 1.00 11.41 ? 218 GLU B C 1 ATOM 6461 O O . GLU B 1 218 ? 35.922 8.822 50.104 1.00 12.28 ? 218 GLU B O 1 ATOM 6462 C CB . GLU B 1 218 ? 33.121 9.247 49.916 1.00 15.77 ? 218 GLU B CB 1 ATOM 6463 C CG . GLU B 1 218 ? 31.627 9.198 50.058 1.00 20.36 ? 218 GLU B CG 1 ATOM 6464 C CD . GLU B 1 218 ? 30.962 9.061 48.696 1.00 21.95 ? 218 GLU B CD 1 ATOM 6465 O OE1 . GLU B 1 218 ? 31.701 8.980 47.689 1.00 23.10 ? 218 GLU B OE1 1 ATOM 6466 O OE2 . GLU B 1 218 ? 29.713 9.035 48.629 1.00 23.77 ? 218 GLU B OE2 1 ATOM 6467 N N . ALA B 1 219 ? 35.974 10.919 50.835 1.00 10.94 ? 219 ALA B N 1 ATOM 6468 C CA . ALA B 1 219 ? 37.339 11.099 50.347 1.00 10.94 ? 219 ALA B CA 1 ATOM 6469 C C . ALA B 1 219 ? 38.154 11.889 51.359 1.00 12.45 ? 219 ALA B C 1 ATOM 6470 O O . ALA B 1 219 ? 37.626 12.772 52.020 1.00 12.88 ? 219 ALA B O 1 ATOM 6471 C CB . ALA B 1 219 ? 37.305 11.832 49.004 1.00 11.12 ? 219 ALA B CB 1 ATOM 6472 N N . TRP B 1 220 ? 39.439 11.579 51.499 1.00 15.00 ? 220 TRP B N 1 ATOM 6473 C CA . TRP B 1 220 ? 40.253 12.322 52.459 1.00 16.81 ? 220 TRP B CA 1 ATOM 6474 C C . TRP B 1 220 ? 41.642 12.718 52.008 1.00 17.63 ? 220 TRP B C 1 ATOM 6475 O O . TRP B 1 220 ? 42.138 12.240 50.975 1.00 17.20 ? 220 TRP B O 1 ATOM 6476 C CB . TRP B 1 220 ? 40.372 11.555 53.768 1.00 24.92 ? 220 TRP B CB 1 ATOM 6477 C CG . TRP B 1 220 ? 39.058 11.133 54.263 1.00 32.76 ? 220 TRP B CG 1 ATOM 6478 C CD1 . TRP B 1 220 ? 38.443 9.938 54.030 1.00 34.84 ? 220 TRP B CD1 1 ATOM 6479 C CD2 . TRP B 1 220 ? 38.119 11.943 54.965 1.00 34.11 ? 220 TRP B CD2 1 ATOM 6480 N NE1 . TRP B 1 220 ? 37.166 9.954 54.538 1.00 37.17 ? 220 TRP B NE1 1 ATOM 6481 C CE2 . TRP B 1 220 ? 36.939 11.179 55.117 1.00 37.04 ? 220 TRP B CE2 1 ATOM 6482 C CE3 . TRP B 1 220 ? 38.153 13.246 55.481 1.00 37.60 ? 220 TRP B CE3 1 ATOM 6483 C CZ2 . TRP B 1 220 ? 35.798 11.676 55.760 1.00 38.83 ? 220 TRP B CZ2 1 ATOM 6484 C CZ3 . TRP B 1 220 ? 37.016 13.740 56.124 1.00 39.45 ? 220 TRP B CZ3 1 ATOM 6485 C CH2 . TRP B 1 220 ? 35.860 12.956 56.252 1.00 39.95 ? 220 TRP B CH2 1 ATOM 6486 N N . ASP B 1 221 ? 42.264 13.581 52.817 1.00 15.20 ? 221 ASP B N 1 ATOM 6487 C CA . ASP B 1 221 ? 43.606 14.097 52.556 1.00 15.64 ? 221 ASP B CA 1 ATOM 6488 C C . ASP B 1 221 ? 44.415 14.243 53.838 1.00 16.19 ? 221 ASP B C 1 ATOM 6489 O O . ASP B 1 221 ? 44.580 15.358 54.342 1.00 16.37 ? 221 ASP B O 1 ATOM 6490 C CB . ASP B 1 221 ? 43.521 15.464 51.862 1.00 17.51 ? 221 ASP B CB 1 ATOM 6491 C CG . ASP B 1 221 ? 44.890 15.992 51.439 1.00 20.93 ? 221 ASP B CG 1 ATOM 6492 O OD1 . ASP B 1 221 ? 45.788 15.152 51.208 1.00 22.93 ? 221 ASP B OD1 1 ATOM 6493 O OD2 . ASP B 1 221 ? 45.068 17.229 51.318 1.00 21.55 ? 221 ASP B OD2 1 ATOM 6494 N N . HIS B 1 222 ? 44.930 13.127 54.356 1.00 16.46 ? 222 HIS B N 1 ATOM 6495 C CA . HIS B 1 222 ? 45.718 13.135 55.595 1.00 17.40 ? 222 HIS B CA 1 ATOM 6496 C C . HIS B 1 222 ? 44.883 13.633 56.787 1.00 16.31 ? 222 HIS B C 1 ATOM 6497 O O . HIS B 1 222 ? 45.392 14.334 57.665 1.00 16.10 ? 222 HIS B O 1 ATOM 6498 C CB . HIS B 1 222 ? 46.948 14.046 55.451 1.00 22.05 ? 222 HIS B CB 1 ATOM 6499 C CG . HIS B 1 222 ? 47.970 13.558 54.470 1.00 25.98 ? 222 HIS B CG 1 ATOM 6500 N ND1 . HIS B 1 222 ? 49.036 14.335 54.065 1.00 26.81 ? 222 HIS B ND1 1 ATOM 6501 C CD2 . HIS B 1 222 ? 48.101 12.373 53.824 1.00 27.28 ? 222 HIS B CD2 1 ATOM 6502 C CE1 . HIS B 1 222 ? 49.777 13.651 53.211 1.00 28.17 ? 222 HIS B CE1 1 ATOM 6503 N NE2 . HIS B 1 222 ? 49.233 12.457 53.048 1.00 28.62 ? 222 HIS B NE2 1 ATOM 6504 N N . GLY B 1 223 ? 43.607 13.277 56.830 1.00 13.96 ? 223 GLY B N 1 ATOM 6505 C CA . GLY B 1 223 ? 42.780 13.749 57.924 1.00 11.16 ? 223 GLY B CA 1 ATOM 6506 C C . GLY B 1 223 ? 42.359 15.188 57.682 1.00 9.83 ? 223 GLY B C 1 ATOM 6507 O O . GLY B 1 223 ? 42.016 15.923 58.613 1.00 11.87 ? 223 GLY B O 1 ATOM 6508 N N . LEU B 1 224 ? 42.411 15.600 56.422 1.00 6.69 ? 224 LEU B N 1 ATOM 6509 C CA . LEU B 1 224 ? 42.008 16.943 56.035 1.00 4.53 ? 224 LEU B CA 1 ATOM 6510 C C . LEU B 1 224 ? 40.945 16.720 54.982 1.00 2.02 ? 224 LEU B C 1 ATOM 6511 O O . LEU B 1 224 ? 40.975 15.706 54.289 1.00 2.00 ? 224 LEU B O 1 ATOM 6512 C CB . LEU B 1 224 ? 43.205 17.743 55.504 1.00 3.33 ? 224 LEU B CB 1 ATOM 6513 C CG . LEU B 1 224 ? 44.199 18.157 56.603 1.00 2.00 ? 224 LEU B CG 1 ATOM 6514 C CD1 . LEU B 1 224 ? 45.304 19.029 56.060 1.00 2.00 ? 224 LEU B CD1 1 ATOM 6515 C CD2 . LEU B 1 224 ? 43.447 18.913 57.672 1.00 2.00 ? 224 LEU B CD2 1 ATOM 6516 N N . ALA B 1 225 ? 40.011 17.660 54.867 1.00 2.00 ? 225 ALA B N 1 ATOM 6517 C CA . ALA B 1 225 ? 38.882 17.510 53.954 1.00 2.00 ? 225 ALA B CA 1 ATOM 6518 C C . ALA B 1 225 ? 38.920 18.106 52.563 1.00 2.00 ? 225 ALA B C 1 ATOM 6519 O O . ALA B 1 225 ? 39.725 18.981 52.240 1.00 2.13 ? 225 ALA B O 1 ATOM 6520 C CB . ALA B 1 225 ? 37.614 17.984 54.648 1.00 3.28 ? 225 ALA B CB 1 ATOM 6521 N N . TYR B 1 226 ? 38.002 17.603 51.749 1.00 2.00 ? 226 TYR B N 1 ATOM 6522 C CA . TYR B 1 226 ? 37.821 18.040 50.377 1.00 2.00 ? 226 TYR B CA 1 ATOM 6523 C C . TYR B 1 226 ? 36.383 18.532 50.327 1.00 2.00 ? 226 TYR B C 1 ATOM 6524 O O . TYR B 1 226 ? 35.588 18.222 51.204 1.00 2.00 ? 226 TYR B O 1 ATOM 6525 C CB . TYR B 1 226 ? 37.921 16.861 49.405 1.00 3.47 ? 226 TYR B CB 1 ATOM 6526 C CG . TYR B 1 226 ? 39.264 16.176 49.246 1.00 2.67 ? 226 TYR B CG 1 ATOM 6527 C CD1 . TYR B 1 226 ? 39.366 14.797 49.376 1.00 2.00 ? 226 TYR B CD1 1 ATOM 6528 C CD2 . TYR B 1 226 ? 40.394 16.878 48.837 1.00 2.00 ? 226 TYR B CD2 1 ATOM 6529 C CE1 . TYR B 1 226 ? 40.542 14.132 49.093 1.00 2.75 ? 226 TYR B CE1 1 ATOM 6530 C CE2 . TYR B 1 226 ? 41.584 16.215 48.551 1.00 2.83 ? 226 TYR B CE2 1 ATOM 6531 C CZ . TYR B 1 226 ? 41.646 14.838 48.677 1.00 3.05 ? 226 TYR B CZ 1 ATOM 6532 O OH . TYR B 1 226 ? 42.795 14.145 48.355 1.00 4.43 ? 226 TYR B OH 1 ATOM 6533 N N . PRO B 1 227 ? 36.030 19.314 49.309 1.00 2.11 ? 227 PRO B N 1 ATOM 6534 C CA . PRO B 1 227 ? 34.635 19.763 49.271 1.00 2.92 ? 227 PRO B CA 1 ATOM 6535 C C . PRO B 1 227 ? 33.737 18.547 48.993 1.00 3.13 ? 227 PRO B C 1 ATOM 6536 O O . PRO B 1 227 ? 34.229 17.497 48.577 1.00 5.55 ? 227 PRO B O 1 ATOM 6537 C CB . PRO B 1 227 ? 34.634 20.759 48.118 1.00 2.90 ? 227 PRO B CB 1 ATOM 6538 C CG . PRO B 1 227 ? 36.018 21.359 48.211 1.00 3.58 ? 227 PRO B CG 1 ATOM 6539 C CD . PRO B 1 227 ? 36.883 20.144 48.441 1.00 2.48 ? 227 PRO B CD 1 ATOM 6540 N N . PRO B 1 228 ? 32.419 18.664 49.229 1.00 2.08 ? 228 PRO B N 1 ATOM 6541 C CA . PRO B 1 228 ? 31.509 17.543 48.980 1.00 2.00 ? 228 PRO B CA 1 ATOM 6542 C C . PRO B 1 228 ? 31.395 17.304 47.495 1.00 2.00 ? 228 PRO B C 1 ATOM 6543 O O . PRO B 1 228 ? 31.422 18.254 46.716 1.00 2.15 ? 228 PRO B O 1 ATOM 6544 C CB . PRO B 1 228 ? 30.186 18.031 49.545 1.00 2.00 ? 228 PRO B CB 1 ATOM 6545 C CG . PRO B 1 228 ? 30.595 19.000 50.589 1.00 2.69 ? 228 PRO B CG 1 ATOM 6546 C CD . PRO B 1 228 ? 31.711 19.752 49.917 1.00 2.46 ? 228 PRO B CD 1 ATOM 6547 N N . PHE B 1 229 ? 31.267 16.042 47.102 1.00 2.47 ? 229 PHE B N 1 ATOM 6548 C CA . PHE B 1 229 ? 31.134 15.711 45.695 1.00 3.57 ? 229 PHE B CA 1 ATOM 6549 C C . PHE B 1 229 ? 29.831 16.256 45.206 1.00 5.66 ? 229 PHE B C 1 ATOM 6550 O O . PHE B 1 229 ? 28.855 16.280 45.942 1.00 5.04 ? 229 PHE B O 1 ATOM 6551 C CB . PHE B 1 229 ? 31.130 14.214 45.473 1.00 2.39 ? 229 PHE B CB 1 ATOM 6552 C CG . PHE B 1 229 ? 32.481 13.604 45.500 1.00 3.14 ? 229 PHE B CG 1 ATOM 6553 C CD1 . PHE B 1 229 ? 33.558 14.253 44.907 1.00 2.71 ? 229 PHE B CD1 1 ATOM 6554 C CD2 . PHE B 1 229 ? 32.674 12.350 46.068 1.00 3.91 ? 229 PHE B CD2 1 ATOM 6555 C CE1 . PHE B 1 229 ? 34.814 13.660 44.873 1.00 4.14 ? 229 PHE B CE1 1 ATOM 6556 C CE2 . PHE B 1 229 ? 33.920 11.745 46.043 1.00 4.46 ? 229 PHE B CE2 1 ATOM 6557 C CZ . PHE B 1 229 ? 35.000 12.401 45.441 1.00 3.97 ? 229 PHE B CZ 1 ATOM 6558 N N . ASN B 1 230 ? 29.805 16.687 43.957 1.00 10.32 ? 230 ASN B N 1 ATOM 6559 C CA . ASN B 1 230 ? 28.582 17.232 43.416 1.00 15.81 ? 230 ASN B CA 1 ATOM 6560 C C . ASN B 1 230 ? 27.613 16.114 43.093 1.00 21.12 ? 230 ASN B C 1 ATOM 6561 O O . ASN B 1 230 ? 28.006 15.016 42.702 1.00 21.52 ? 230 ASN B O 1 ATOM 6562 C CB . ASN B 1 230 ? 28.860 18.053 42.173 1.00 16.39 ? 230 ASN B CB 1 ATOM 6563 C CG . ASN B 1 230 ? 27.604 18.571 41.548 1.00 16.02 ? 230 ASN B CG 1 ATOM 6564 O OD1 . ASN B 1 230 ? 26.745 19.116 42.232 1.00 16.63 ? 230 ASN B OD1 1 ATOM 6565 N ND2 . ASN B 1 230 ? 27.483 18.408 40.241 1.00 18.63 ? 230 ASN B ND2 1 ATOM 6566 N N . ASN B 1 231 ? 26.334 16.411 43.260 1.00 26.21 ? 231 ASN B N 1 ATOM 6567 C CA . ASN B 1 231 ? 25.278 15.438 43.023 1.00 29.72 ? 231 ASN B CA 1 ATOM 6568 C C . ASN B 1 231 ? 25.130 14.989 41.572 1.00 30.46 ? 231 ASN B C 1 ATOM 6569 O O . ASN B 1 231 ? 25.748 14.018 41.140 1.00 29.89 ? 231 ASN B O 1 ATOM 6570 C CB . ASN B 1 231 ? 23.948 16.022 43.497 1.00 33.88 ? 231 ASN B CB 1 ATOM 6571 C CG . ASN B 1 231 ? 23.549 15.538 44.871 1.00 37.10 ? 231 ASN B CG 1 ATOM 6572 O OD1 . ASN B 1 231 ? 24.398 15.138 45.671 1.00 38.51 ? 231 ASN B OD1 1 ATOM 6573 N ND2 . ASN B 1 231 ? 22.245 15.585 45.161 1.00 37.95 ? 231 ASN B ND2 1 ATOM 6574 N N . MET B 1 232 ? 24.278 15.730 40.874 1.00 32.26 ? 232 MET B N 1 ATOM 6575 C CA . MET B 1 232 ? 23.912 15.521 39.494 1.00 33.33 ? 232 MET B CA 1 ATOM 6576 C C . MET B 1 232 ? 24.753 14.585 38.650 1.00 32.23 ? 232 MET B C 1 ATOM 6577 O O . MET B 1 232 ? 25.966 14.760 38.519 1.00 29.43 ? 232 MET B O 1 ATOM 6578 C CB . MET B 1 232 ? 23.827 16.869 38.754 1.00 37.15 ? 232 MET B CB 1 ATOM 6579 C CG . MET B 1 232 ? 22.552 17.064 37.950 1.00 41.59 ? 232 MET B CG 1 ATOM 6580 S SD . MET B 1 232 ? 21.654 18.564 38.508 1.00 48.29 ? 232 MET B SD 1 ATOM 6581 C CE . MET B 1 232 ? 19.907 17.961 38.584 1.00 47.18 ? 232 MET B CE 1 ATOM 6582 N N . LYS B 1 233 ? 24.101 13.579 38.092 1.00 32.39 ? 233 LYS B N 1 ATOM 6583 C CA . LYS B 1 233 ? 24.772 12.691 37.162 1.00 30.82 ? 233 LYS B CA 1 ATOM 6584 C C . LYS B 1 233 ? 24.498 13.326 35.793 1.00 29.89 ? 233 LYS B C 1 ATOM 6585 O O . LYS B 1 233 ? 23.481 14.026 35.658 1.00 31.14 ? 233 LYS B O 1 ATOM 6586 C CB . LYS B 1 233 ? 24.186 11.263 37.278 1.00 31.84 ? 233 LYS B CB 1 ATOM 6587 C CG . LYS B 1 233 ? 24.797 10.467 38.440 1.00 34.54 ? 233 LYS B CG 1 ATOM 6588 C CD . LYS B 1 233 ? 26.267 10.110 38.115 1.00 35.25 ? 233 LYS B CD 1 ATOM 6589 C CE . LYS B 1 233 ? 26.968 9.360 39.276 1.00 37.02 ? 233 LYS B CE 1 ATOM 6590 N NZ . LYS B 1 233 ? 27.788 8.170 38.817 1.00 36.53 ? 233 LYS B NZ 1 ATOM 6591 N N . PRO B 1 234 ? 25.471 13.266 34.851 1.00 26.96 ? 234 PRO B N 1 ATOM 6592 C CA . PRO B 1 234 ? 26.279 13.412 33.665 1.00 24.24 ? 234 PRO B CA 1 ATOM 6593 C C . PRO B 1 234 ? 27.203 14.553 33.894 1.00 22.65 ? 234 PRO B C 1 ATOM 6594 O O . PRO B 1 234 ? 27.137 15.599 33.259 1.00 24.01 ? 234 PRO B O 1 ATOM 6595 C CB . PRO B 1 234 ? 25.201 13.722 32.620 1.00 24.39 ? 234 PRO B CB 1 ATOM 6596 C CG . PRO B 1 234 ? 24.168 12.714 32.958 1.00 26.94 ? 234 PRO B CG 1 ATOM 6597 C CD . PRO B 1 234 ? 24.570 12.227 34.414 1.00 27.57 ? 234 PRO B CD 1 ATOM 6598 N N . SER B 1 235 ? 28.005 14.362 34.917 1.00 18.93 ? 235 SER B N 1 ATOM 6599 C CA . SER B 1 235 ? 28.987 15.356 35.311 1.00 14.81 ? 235 SER B CA 1 ATOM 6600 C C . SER B 1 235 ? 30.190 15.075 34.443 1.00 13.14 ? 235 SER B C 1 ATOM 6601 O O . SER B 1 235 ? 30.439 13.940 34.074 1.00 13.72 ? 235 SER B O 1 ATOM 6602 C CB . SER B 1 235 ? 29.371 15.205 36.782 1.00 13.89 ? 235 SER B CB 1 ATOM 6603 O OG . SER B 1 235 ? 30.267 14.129 36.907 1.00 11.64 ? 235 SER B OG 1 ATOM 6604 N N . PRO B 1 236 ? 30.965 16.112 34.110 1.00 11.18 ? 236 PRO B N 1 ATOM 6605 C CA . PRO B 1 236 ? 32.118 15.813 33.266 1.00 8.34 ? 236 PRO B CA 1 ATOM 6606 C C . PRO B 1 236 ? 33.345 15.289 34.002 1.00 7.67 ? 236 PRO B C 1 ATOM 6607 O O . PRO B 1 236 ? 34.079 14.482 33.450 1.00 7.68 ? 236 PRO B O 1 ATOM 6608 C CB . PRO B 1 236 ? 32.362 17.136 32.547 1.00 10.38 ? 236 PRO B CB 1 ATOM 6609 C CG . PRO B 1 236 ? 31.990 18.141 33.583 1.00 9.74 ? 236 PRO B CG 1 ATOM 6610 C CD . PRO B 1 236 ? 30.728 17.567 34.196 1.00 10.57 ? 236 PRO B CD 1 ATOM 6611 N N . CYS B 1 237 ? 33.578 15.716 35.241 1.00 6.83 ? 237 CYS B N 1 ATOM 6612 C CA . CYS B 1 237 ? 34.758 15.225 35.968 1.00 7.01 ? 237 CYS B CA 1 ATOM 6613 C C . CYS B 1 237 ? 34.833 13.705 36.005 1.00 8.35 ? 237 CYS B C 1 ATOM 6614 O O . CYS B 1 237 ? 35.885 13.145 36.320 1.00 8.11 ? 237 CYS B O 1 ATOM 6615 C CB . CYS B 1 237 ? 34.799 15.754 37.404 1.00 7.21 ? 237 CYS B CB 1 ATOM 6616 S SG . CYS B 1 237 ? 34.801 17.561 37.473 1.00 4.98 ? 237 CYS B SG 1 ATOM 6617 N N . GLU B 1 238 ? 33.714 13.043 35.712 1.00 9.32 ? 238 GLU B N 1 ATOM 6618 C CA . GLU B 1 238 ? 33.665 11.583 35.684 1.00 10.35 ? 238 GLU B CA 1 ATOM 6619 C C . GLU B 1 238 ? 34.138 11.099 34.315 1.00 12.17 ? 238 GLU B C 1 ATOM 6620 O O . GLU B 1 238 ? 34.959 10.182 34.207 1.00 11.79 ? 238 GLU B O 1 ATOM 6621 C CB . GLU B 1 238 ? 32.239 11.078 35.892 1.00 11.52 ? 238 GLU B CB 1 ATOM 6622 C CG . GLU B 1 238 ? 31.666 11.245 37.280 1.00 14.85 ? 238 GLU B CG 1 ATOM 6623 C CD . GLU B 1 238 ? 30.482 10.307 37.513 1.00 16.35 ? 238 GLU B CD 1 ATOM 6624 O OE1 . GLU B 1 238 ? 29.858 10.367 38.598 1.00 18.43 ? 238 GLU B OE1 1 ATOM 6625 O OE2 . GLU B 1 238 ? 30.180 9.500 36.604 1.00 17.59 ? 238 GLU B OE2 1 ATOM 6626 N N . PHE B 1 239 ? 33.588 11.722 33.276 1.00 12.08 ? 239 PHE B N 1 ATOM 6627 C CA . PHE B 1 239 ? 33.902 11.399 31.890 1.00 12.31 ? 239 PHE B CA 1 ATOM 6628 C C . PHE B 1 239 ? 35.410 11.301 31.667 1.00 13.17 ? 239 PHE B C 1 ATOM 6629 O O . PHE B 1 239 ? 35.904 10.263 31.219 1.00 14.21 ? 239 PHE B O 1 ATOM 6630 C CB . PHE B 1 239 ? 33.314 12.470 30.975 1.00 14.62 ? 239 PHE B CB 1 ATOM 6631 C CG . PHE B 1 239 ? 33.260 12.082 29.522 1.00 16.76 ? 239 PHE B CG 1 ATOM 6632 C CD1 . PHE B 1 239 ? 32.671 10.884 29.126 1.00 18.16 ? 239 PHE B CD1 1 ATOM 6633 C CD2 . PHE B 1 239 ? 33.716 12.962 28.539 1.00 17.16 ? 239 PHE B CD2 1 ATOM 6634 C CE1 . PHE B 1 239 ? 32.530 10.575 27.765 1.00 20.21 ? 239 PHE B CE1 1 ATOM 6635 C CE2 . PHE B 1 239 ? 33.581 12.668 27.178 1.00 17.03 ? 239 PHE B CE2 1 ATOM 6636 C CZ . PHE B 1 239 ? 32.985 11.476 26.787 1.00 19.11 ? 239 PHE B CZ 1 ATOM 6637 N N . ILE B 1 240 ? 36.129 12.376 32.001 1.00 11.26 ? 240 ILE B N 1 ATOM 6638 C CA . ILE B 1 240 ? 37.578 12.441 31.823 1.00 9.90 ? 240 ILE B CA 1 ATOM 6639 C C . ILE B 1 240 ? 38.293 11.098 32.041 1.00 9.60 ? 240 ILE B C 1 ATOM 6640 O O . ILE B 1 240 ? 39.006 10.651 31.141 1.00 10.69 ? 240 ILE B O 1 ATOM 6641 C CB . ILE B 1 240 ? 38.201 13.562 32.685 1.00 7.97 ? 240 ILE B CB 1 ATOM 6642 C CG1 . ILE B 1 240 ? 37.764 14.934 32.149 1.00 8.54 ? 240 ILE B CG1 1 ATOM 6643 C CG2 . ILE B 1 240 ? 39.711 13.491 32.615 1.00 10.38 ? 240 ILE B CG2 1 ATOM 6644 C CD1 . ILE B 1 240 ? 38.040 15.137 30.672 1.00 5.84 ? 240 ILE B CD1 1 ATOM 6645 N N . ASN B 1 241 ? 38.143 10.471 33.211 1.00 8.42 ? 241 ASN B N 1 ATOM 6646 C CA . ASN B 1 241 ? 38.720 9.130 33.453 1.00 7.86 ? 241 ASN B CA 1 ATOM 6647 C C . ASN B 1 241 ? 37.521 8.301 33.854 1.00 8.63 ? 241 ASN B C 1 ATOM 6648 O O . ASN B 1 241 ? 37.108 8.300 35.012 1.00 7.08 ? 241 ASN B O 1 ATOM 6649 C CB . ASN B 1 241 ? 39.748 9.063 34.598 1.00 10.14 ? 241 ASN B CB 1 ATOM 6650 C CG . ASN B 1 241 ? 40.298 7.631 34.828 1.00 13.38 ? 241 ASN B CG 1 ATOM 6651 O OD1 . ASN B 1 241 ? 39.581 6.697 35.156 1.00 9.12 ? 241 ASN B OD1 1 ATOM 6652 N ND2 . ASN B 1 241 ? 41.597 7.480 34.612 1.00 21.92 ? 241 ASN B ND2 1 ATOM 6653 N N . THR B 1 242 ? 36.939 7.631 32.872 1.00 10.18 ? 242 THR B N 1 ATOM 6654 C CA . THR B 1 242 ? 35.777 6.788 33.097 1.00 11.66 ? 242 THR B CA 1 ATOM 6655 C C . THR B 1 242 ? 36.006 5.771 34.210 1.00 12.84 ? 242 THR B C 1 ATOM 6656 O O . THR B 1 242 ? 35.119 5.504 35.018 1.00 13.01 ? 242 THR B O 1 ATOM 6657 C CB . THR B 1 242 ? 35.427 6.023 31.829 1.00 12.18 ? 242 THR B CB 1 ATOM 6658 O OG1 . THR B 1 242 ? 36.346 6.394 30.786 1.00 11.42 ? 242 THR B OG1 1 ATOM 6659 C CG2 . THR B 1 242 ? 33.996 6.332 31.413 1.00 13.45 ? 242 THR B CG2 1 ATOM 6660 N N . THR B 1 243 ? 37.206 5.207 34.244 1.00 14.30 ? 243 THR B N 1 ATOM 6661 C CA . THR B 1 243 ? 37.553 4.203 35.243 1.00 14.04 ? 243 THR B CA 1 ATOM 6662 C C . THR B 1 243 ? 37.500 4.746 36.666 1.00 14.52 ? 243 THR B C 1 ATOM 6663 O O . THR B 1 243 ? 36.716 4.273 37.488 1.00 14.08 ? 243 THR B O 1 ATOM 6664 C CB . THR B 1 243 ? 38.966 3.628 34.976 1.00 14.36 ? 243 THR B CB 1 ATOM 6665 O OG1 . THR B 1 243 ? 38.942 2.835 33.784 1.00 12.11 ? 243 THR B OG1 1 ATOM 6666 C CG2 . THR B 1 243 ? 39.429 2.779 36.146 1.00 14.57 ? 243 THR B CG2 1 ATOM 6667 N N . ALA B 1 244 ? 38.346 5.737 36.937 1.00 15.50 ? 244 ALA B N 1 ATOM 6668 C CA . ALA B 1 244 ? 38.445 6.375 38.247 1.00 15.31 ? 244 ALA B CA 1 ATOM 6669 C C . ALA B 1 244 ? 37.086 6.674 38.865 1.00 15.75 ? 244 ALA B C 1 ATOM 6670 O O . ALA B 1 244 ? 36.876 6.418 40.050 1.00 14.49 ? 244 ALA B O 1 ATOM 6671 C CB . ALA B 1 244 ? 39.266 7.661 38.135 1.00 14.96 ? 244 ALA B CB 1 ATOM 6672 N N . ARG B 1 245 ? 36.174 7.225 38.066 1.00 17.43 ? 245 ARG B N 1 ATOM 6673 C CA . ARG B 1 245 ? 34.821 7.552 38.527 1.00 18.86 ? 245 ARG B CA 1 ATOM 6674 C C . ARG B 1 245 ? 34.726 8.480 39.746 1.00 17.85 ? 245 ARG B C 1 ATOM 6675 O O . ARG B 1 245 ? 33.982 8.196 40.692 1.00 17.30 ? 245 ARG B O 1 ATOM 6676 C CB . ARG B 1 245 ? 34.053 6.265 38.833 1.00 23.52 ? 245 ARG B CB 1 ATOM 6677 C CG . ARG B 1 245 ? 33.607 5.495 37.612 1.00 29.63 ? 245 ARG B CG 1 ATOM 6678 C CD . ARG B 1 245 ? 33.290 4.061 37.993 1.00 34.61 ? 245 ARG B CD 1 ATOM 6679 N NE . ARG B 1 245 ? 32.329 3.985 39.089 1.00 39.41 ? 245 ARG B NE 1 ATOM 6680 C CZ . ARG B 1 245 ? 32.526 3.289 40.204 1.00 41.46 ? 245 ARG B CZ 1 ATOM 6681 N NH1 . ARG B 1 245 ? 33.657 2.607 40.373 1.00 42.88 ? 245 ARG B NH1 1 ATOM 6682 N NH2 . ARG B 1 245 ? 31.588 3.268 41.145 1.00 42.68 ? 245 ARG B NH2 1 ATOM 6683 N N . VAL B 1 246 ? 35.480 9.576 39.723 1.00 15.42 ? 246 VAL B N 1 ATOM 6684 C CA . VAL B 1 246 ? 35.457 10.555 40.809 1.00 13.39 ? 246 VAL B CA 1 ATOM 6685 C C . VAL B 1 246 ? 34.882 11.838 40.220 1.00 13.02 ? 246 VAL B C 1 ATOM 6686 O O . VAL B 1 246 ? 35.475 12.439 39.324 1.00 15.14 ? 246 VAL B O 1 ATOM 6687 C CB . VAL B 1 246 ? 36.873 10.880 41.351 1.00 12.47 ? 246 VAL B CB 1 ATOM 6688 C CG1 . VAL B 1 246 ? 36.846 10.897 42.871 1.00 12.82 ? 246 VAL B CG1 1 ATOM 6689 C CG2 . VAL B 1 246 ? 37.887 9.885 40.830 1.00 10.52 ? 246 VAL B CG2 1 ATOM 6690 N N . PRO B 1 247 ? 33.719 12.277 40.712 1.00 10.26 ? 247 PRO B N 1 ATOM 6691 C CA . PRO B 1 247 ? 33.113 13.498 40.186 1.00 10.13 ? 247 PRO B CA 1 ATOM 6692 C C . PRO B 1 247 ? 33.732 14.812 40.664 1.00 9.28 ? 247 PRO B C 1 ATOM 6693 O O . PRO B 1 247 ? 34.703 14.837 41.426 1.00 9.04 ? 247 PRO B O 1 ATOM 6694 C CB . PRO B 1 247 ? 31.665 13.365 40.626 1.00 9.92 ? 247 PRO B CB 1 ATOM 6695 C CG . PRO B 1 247 ? 31.813 12.729 41.961 1.00 10.47 ? 247 PRO B CG 1 ATOM 6696 C CD . PRO B 1 247 ? 32.822 11.632 41.683 1.00 10.42 ? 247 PRO B CD 1 ATOM 6697 N N . CYS B 1 248 ? 33.131 15.901 40.197 1.00 7.79 ? 248 CYS B N 1 ATOM 6698 C CA . CYS B 1 248 ? 33.549 17.248 40.522 1.00 5.48 ? 248 CYS B CA 1 ATOM 6699 C C . CYS B 1 248 ? 33.202 17.609 41.942 1.00 5.88 ? 248 CYS B C 1 ATOM 6700 O O . CYS B 1 248 ? 32.327 17.014 42.559 1.00 4.92 ? 248 CYS B O 1 ATOM 6701 C CB . CYS B 1 248 ? 32.827 18.254 39.648 1.00 6.28 ? 248 CYS B CB 1 ATOM 6702 S SG . CYS B 1 248 ? 32.861 17.967 37.863 1.00 7.80 ? 248 CYS B SG 1 ATOM 6703 N N . PHE B 1 249 ? 33.878 18.624 42.441 1.00 6.40 ? 249 PHE B N 1 ATOM 6704 C CA . PHE B 1 249 ? 33.618 19.109 43.770 1.00 6.76 ? 249 PHE B CA 1 ATOM 6705 C C . PHE B 1 249 ? 32.486 20.089 43.617 1.00 7.20 ? 249 PHE B C 1 ATOM 6706 O O . PHE B 1 249 ? 32.268 20.627 42.533 1.00 6.73 ? 249 PHE B O 1 ATOM 6707 C CB . PHE B 1 249 ? 34.838 19.834 44.315 1.00 8.87 ? 249 PHE B CB 1 ATOM 6708 C CG . PHE B 1 249 ? 35.971 18.924 44.679 1.00 10.17 ? 249 PHE B CG 1 ATOM 6709 C CD1 . PHE B 1 249 ? 35.730 17.737 45.360 1.00 10.80 ? 249 PHE B CD1 1 ATOM 6710 C CD2 . PHE B 1 249 ? 37.282 19.293 44.417 1.00 10.66 ? 249 PHE B CD2 1 ATOM 6711 C CE1 . PHE B 1 249 ? 36.777 16.939 45.780 1.00 11.44 ? 249 PHE B CE1 1 ATOM 6712 C CE2 . PHE B 1 249 ? 38.339 18.502 44.835 1.00 11.37 ? 249 PHE B CE2 1 ATOM 6713 C CZ . PHE B 1 249 ? 38.087 17.323 45.520 1.00 12.14 ? 249 PHE B CZ 1 ATOM 6714 N N . GLN B 1 250 ? 31.755 20.322 44.694 1.00 8.91 ? 250 GLN B N 1 ATOM 6715 C CA . GLN B 1 250 ? 30.665 21.273 44.624 1.00 10.27 ? 250 GLN B CA 1 ATOM 6716 C C . GLN B 1 250 ? 30.931 22.404 45.594 1.00 10.69 ? 250 GLN B C 1 ATOM 6717 O O . GLN B 1 250 ? 31.179 22.183 46.782 1.00 11.31 ? 250 GLN B O 1 ATOM 6718 C CB . GLN B 1 250 ? 29.344 20.581 44.929 1.00 12.22 ? 250 GLN B CB 1 ATOM 6719 C CG . GLN B 1 250 ? 28.145 21.237 44.284 1.00 18.24 ? 250 GLN B CG 1 ATOM 6720 C CD . GLN B 1 250 ? 26.887 20.931 45.054 1.00 21.38 ? 250 GLN B CD 1 ATOM 6721 O OE1 . GLN B 1 250 ? 26.768 19.889 45.697 1.00 22.80 ? 250 GLN B OE1 1 ATOM 6722 N NE2 . GLN B 1 250 ? 25.799 21.700 45.114 1.00 24.26 ? 250 GLN B NE2 1 ATOM 6723 N N . ALA B 1 251 ? 30.849 23.624 45.079 1.00 9.32 ? 251 ALA B N 1 ATOM 6724 C CA . ALA B 1 251 ? 31.141 24.816 45.902 1.00 7.92 ? 251 ALA B CA 1 ATOM 6725 C C . ALA B 1 251 ? 30.230 25.956 45.525 1.00 7.32 ? 251 ALA B C 1 ATOM 6726 O O . ALA B 1 251 ? 29.568 25.939 44.483 1.00 6.67 ? 251 ALA B O 1 ATOM 6727 C CB . ALA B 1 251 ? 32.596 25.220 45.762 1.00 7.54 ? 251 ALA B CB 1 ATOM 6728 N N . GLY B 1 252 ? 30.192 26.948 46.400 1.00 6.35 ? 252 GLY B N 1 ATOM 6729 C CA . GLY B 1 252 ? 29.349 28.121 46.223 1.00 5.71 ? 252 GLY B CA 1 ATOM 6730 C C . GLY B 1 252 ? 29.282 28.543 44.754 1.00 4.12 ? 252 GLY B C 1 ATOM 6731 O O . GLY B 1 252 ? 28.292 29.091 44.298 1.00 5.64 ? 252 GLY B O 1 ATOM 6732 N N . ASP B 1 253 ? 30.344 28.284 44.005 1.00 3.32 ? 253 ASP B N 1 ATOM 6733 C CA . ASP B 1 253 ? 30.393 28.653 42.597 1.00 2.91 ? 253 ASP B CA 1 ATOM 6734 C C . ASP B 1 253 ? 30.404 27.373 41.764 1.00 2.99 ? 253 ASP B C 1 ATOM 6735 O O . ASP B 1 253 ? 30.881 26.332 42.225 1.00 2.93 ? 253 ASP B O 1 ATOM 6736 C CB . ASP B 1 253 ? 31.649 29.472 42.311 1.00 3.08 ? 253 ASP B CB 1 ATOM 6737 C CG . ASP B 1 253 ? 31.758 29.882 40.856 1.00 2.99 ? 253 ASP B CG 1 ATOM 6738 O OD1 . ASP B 1 253 ? 31.187 30.929 40.480 1.00 2.00 ? 253 ASP B OD1 1 ATOM 6739 O OD2 . ASP B 1 253 ? 32.412 29.142 40.088 1.00 3.53 ? 253 ASP B OD2 1 ATOM 6740 N N . SER B 1 254 ? 29.893 27.446 40.538 1.00 2.22 ? 254 SER B N 1 ATOM 6741 C CA . SER B 1 254 ? 29.836 26.263 39.688 1.00 3.20 ? 254 SER B CA 1 ATOM 6742 C C . SER B 1 254 ? 31.019 26.040 38.746 1.00 2.68 ? 254 SER B C 1 ATOM 6743 O O . SER B 1 254 ? 31.012 25.091 37.969 1.00 3.92 ? 254 SER B O 1 ATOM 6744 C CB . SER B 1 254 ? 28.531 26.249 38.874 1.00 2.61 ? 254 SER B CB 1 ATOM 6745 O OG . SER B 1 254 ? 28.512 27.253 37.870 1.00 2.00 ? 254 SER B OG 1 ATOM 6746 N N . ARG B 1 255 ? 32.034 26.886 38.789 1.00 2.00 ? 255 ARG B N 1 ATOM 6747 C CA . ARG B 1 255 ? 33.157 26.642 37.900 1.00 2.00 ? 255 ARG B CA 1 ATOM 6748 C C . ARG B 1 255 ? 34.318 26.054 38.662 1.00 3.30 ? 255 ARG B C 1 ATOM 6749 O O . ARG B 1 255 ? 35.387 25.813 38.104 1.00 2.00 ? 255 ARG B O 1 ATOM 6750 C CB . ARG B 1 255 ? 33.653 27.924 37.233 1.00 2.00 ? 255 ARG B CB 1 ATOM 6751 C CG . ARG B 1 255 ? 32.614 28.564 36.351 1.00 2.11 ? 255 ARG B CG 1 ATOM 6752 C CD . ARG B 1 255 ? 31.890 29.641 37.129 1.00 3.12 ? 255 ARG B CD 1 ATOM 6753 N NE . ARG B 1 255 ? 32.119 30.935 36.531 1.00 2.36 ? 255 ARG B NE 1 ATOM 6754 C CZ . ARG B 1 255 ? 32.251 32.069 37.207 1.00 2.84 ? 255 ARG B CZ 1 ATOM 6755 N NH1 . ARG B 1 255 ? 32.218 32.071 38.535 1.00 2.00 ? 255 ARG B NH1 1 ATOM 6756 N NH2 . ARG B 1 255 ? 32.425 33.205 36.549 1.00 4.59 ? 255 ARG B NH2 1 ATOM 6757 N N . ALA B 1 256 ? 34.097 25.847 39.976 1.00 4.78 ? 256 ALA B N 1 ATOM 6758 C CA . ALA B 1 256 ? 35.136 25.327 40.845 1.00 2.00 ? 256 ALA B CA 1 ATOM 6759 C C . ALA B 1 256 ? 36.018 24.228 40.232 1.00 2.00 ? 256 ALA B C 1 ATOM 6760 O O . ALA B 1 256 ? 37.180 24.127 40.605 1.00 3.74 ? 256 ALA B O 1 ATOM 6761 C CB . ALA B 1 256 ? 34.506 24.796 42.124 1.00 2.00 ? 256 ALA B CB 1 ATOM 6762 N N . SER B 1 257 ? 35.522 23.395 39.312 1.00 2.17 ? 257 SER B N 1 ATOM 6763 C CA . SER B 1 257 ? 36.361 22.255 38.856 1.00 2.00 ? 257 SER B CA 1 ATOM 6764 C C . SER B 1 257 ? 37.078 22.476 37.533 1.00 2.65 ? 257 SER B C 1 ATOM 6765 O O . SER B 1 257 ? 37.940 21.677 37.172 1.00 2.56 ? 257 SER B O 1 ATOM 6766 C CB . SER B 1 257 ? 35.497 20.990 38.731 1.00 2.00 ? 257 SER B CB 1 ATOM 6767 O OG . SER B 1 257 ? 35.313 20.356 39.980 1.00 2.00 ? 257 SER B OG 1 ATOM 6768 N N . GLU B 1 258 ? 36.737 23.560 36.804 1.00 3.89 ? 258 GLU B N 1 ATOM 6769 C CA . GLU B 1 258 ? 37.384 23.732 35.497 1.00 2.00 ? 258 GLU B CA 1 ATOM 6770 C C . GLU B 1 258 ? 38.784 23.135 35.531 1.00 2.00 ? 258 GLU B C 1 ATOM 6771 O O . GLU B 1 258 ? 39.077 22.256 34.720 1.00 2.70 ? 258 GLU B O 1 ATOM 6772 C CB . GLU B 1 258 ? 37.483 25.207 35.017 1.00 2.57 ? 258 GLU B CB 1 ATOM 6773 C CG . GLU B 1 258 ? 37.875 25.354 33.537 1.00 2.66 ? 258 GLU B CG 1 ATOM 6774 C CD . GLU B 1 258 ? 39.130 26.217 33.279 1.00 2.55 ? 258 GLU B CD 1 ATOM 6775 O OE1 . GLU B 1 258 ? 39.704 26.715 34.260 1.00 2.00 ? 258 GLU B OE1 1 ATOM 6776 O OE2 . GLU B 1 258 ? 39.510 26.387 32.094 1.00 4.75 ? 258 GLU B OE2 1 ATOM 6777 N N . GLN B 1 259 ? 39.668 23.582 36.458 1.00 2.00 ? 259 GLN B N 1 ATOM 6778 C CA . GLN B 1 259 ? 41.035 23.047 36.444 1.00 2.00 ? 259 GLN B CA 1 ATOM 6779 C C . GLN B 1 259 ? 41.530 22.745 37.862 1.00 3.42 ? 259 GLN B C 1 ATOM 6780 O O . GLN B 1 259 ? 41.331 23.536 38.802 1.00 3.12 ? 259 GLN B O 1 ATOM 6781 C CB . GLN B 1 259 ? 41.964 23.994 35.703 1.00 2.00 ? 259 GLN B CB 1 ATOM 6782 C CG . GLN B 1 259 ? 41.904 25.410 36.187 1.00 2.00 ? 259 GLN B CG 1 ATOM 6783 C CD . GLN B 1 259 ? 43.032 25.688 37.144 1.00 2.00 ? 259 GLN B CD 1 ATOM 6784 O OE1 . GLN B 1 259 ? 43.813 24.787 37.464 1.00 2.00 ? 259 GLN B OE1 1 ATOM 6785 N NE2 . GLN B 1 259 ? 43.308 26.856 37.713 1.00 2.00 ? 259 GLN B NE2 1 ATOM 6786 N N . ILE B 1 260 ? 42.176 21.589 37.987 1.00 3.96 ? 260 ILE B N 1 ATOM 6787 C CA . ILE B 1 260 ? 42.695 21.050 39.237 1.00 2.11 ? 260 ILE B CA 1 ATOM 6788 C C . ILE B 1 260 ? 43.319 22.035 40.212 1.00 2.00 ? 260 ILE B C 1 ATOM 6789 O O . ILE B 1 260 ? 43.272 21.822 41.422 1.00 2.00 ? 260 ILE B O 1 ATOM 6790 C CB . ILE B 1 260 ? 43.693 19.911 38.934 1.00 2.00 ? 260 ILE B CB 1 ATOM 6791 C CG1 . ILE B 1 260 ? 44.038 19.159 40.212 1.00 2.00 ? 260 ILE B CG1 1 ATOM 6792 C CG2 . ILE B 1 260 ? 44.944 20.467 38.288 1.00 2.00 ? 260 ILE B CG2 1 ATOM 6793 C CD1 . ILE B 1 260 ? 44.792 17.875 39.960 1.00 2.00 ? 260 ILE B CD1 1 ATOM 6794 N N . LEU B 1 261 ? 43.904 23.111 39.704 1.00 2.00 ? 261 LEU B N 1 ATOM 6795 C CA . LEU B 1 261 ? 44.509 24.088 40.594 1.00 2.00 ? 261 LEU B CA 1 ATOM 6796 C C . LEU B 1 261 ? 43.464 25.034 41.160 1.00 2.22 ? 261 LEU B C 1 ATOM 6797 O O . LEU B 1 261 ? 43.648 25.609 42.232 1.00 2.00 ? 261 LEU B O 1 ATOM 6798 C CB . LEU B 1 261 ? 45.591 24.873 39.867 1.00 2.00 ? 261 LEU B CB 1 ATOM 6799 C CG . LEU B 1 261 ? 47.035 24.583 40.287 1.00 2.25 ? 261 LEU B CG 1 ATOM 6800 C CD1 . LEU B 1 261 ? 47.118 23.403 41.250 1.00 2.00 ? 261 LEU B CD1 1 ATOM 6801 C CD2 . LEU B 1 261 ? 47.847 24.322 39.030 1.00 2.00 ? 261 LEU B CD2 1 ATOM 6802 N N . LEU B 1 262 ? 42.361 25.196 40.441 1.00 2.45 ? 262 LEU B N 1 ATOM 6803 C CA . LEU B 1 262 ? 41.292 26.056 40.914 1.00 2.00 ? 262 LEU B CA 1 ATOM 6804 C C . LEU B 1 262 ? 40.654 25.324 42.086 1.00 2.00 ? 262 LEU B C 1 ATOM 6805 O O . LEU B 1 262 ? 40.495 25.884 43.167 1.00 2.00 ? 262 LEU B O 1 ATOM 6806 C CB . LEU B 1 262 ? 40.265 26.283 39.810 1.00 2.00 ? 262 LEU B CB 1 ATOM 6807 C CG . LEU B 1 262 ? 39.163 27.265 40.186 1.00 2.00 ? 262 LEU B CG 1 ATOM 6808 C CD1 . LEU B 1 262 ? 39.785 28.581 40.611 1.00 3.52 ? 262 LEU B CD1 1 ATOM 6809 C CD2 . LEU B 1 262 ? 38.235 27.467 39.011 1.00 2.00 ? 262 LEU B CD2 1 ATOM 6810 N N . ALA B 1 263 ? 40.315 24.058 41.855 1.00 2.41 ? 263 ALA B N 1 ATOM 6811 C CA . ALA B 1 263 ? 39.706 23.200 42.868 1.00 2.00 ? 263 ALA B CA 1 ATOM 6812 C C . ALA B 1 263 ? 40.548 23.209 44.135 1.00 4.41 ? 263 ALA B C 1 ATOM 6813 O O . ALA B 1 263 ? 40.027 23.176 45.252 1.00 4.98 ? 263 ALA B O 1 ATOM 6814 C CB . ALA B 1 263 ? 39.596 21.780 42.344 1.00 2.00 ? 263 ALA B CB 1 ATOM 6815 N N . THR B 1 264 ? 41.860 23.255 43.958 1.00 3.38 ? 264 THR B N 1 ATOM 6816 C CA . THR B 1 264 ? 42.745 23.248 45.097 1.00 2.00 ? 264 THR B CA 1 ATOM 6817 C C . THR B 1 264 ? 42.520 24.428 46.029 1.00 2.00 ? 264 THR B C 1 ATOM 6818 O O . THR B 1 264 ? 42.326 24.228 47.223 1.00 2.71 ? 264 THR B O 1 ATOM 6819 C CB . THR B 1 264 ? 44.203 23.195 44.644 1.00 2.00 ? 264 THR B CB 1 ATOM 6820 O OG1 . THR B 1 264 ? 44.405 21.997 43.885 1.00 2.00 ? 264 THR B OG1 1 ATOM 6821 C CG2 . THR B 1 264 ? 45.141 23.193 45.841 1.00 2.00 ? 264 THR B CG2 1 ATOM 6822 N N . VAL B 1 265 ? 42.511 25.651 45.514 1.00 2.00 ? 265 VAL B N 1 ATOM 6823 C CA . VAL B 1 265 ? 42.322 26.780 46.420 1.00 2.00 ? 265 VAL B CA 1 ATOM 6824 C C . VAL B 1 265 ? 40.919 26.831 46.991 1.00 2.00 ? 265 VAL B C 1 ATOM 6825 O O . VAL B 1 265 ? 40.683 27.445 48.031 1.00 2.00 ? 265 VAL B O 1 ATOM 6826 C CB . VAL B 1 265 ? 42.605 28.120 45.754 1.00 2.00 ? 265 VAL B CB 1 ATOM 6827 C CG1 . VAL B 1 265 ? 43.195 29.072 46.783 1.00 2.00 ? 265 VAL B CG1 1 ATOM 6828 C CG2 . VAL B 1 265 ? 43.538 27.936 44.589 1.00 2.12 ? 265 VAL B CG2 1 ATOM 6829 N N . HIS B 1 266 ? 39.988 26.190 46.298 1.00 2.00 ? 266 HIS B N 1 ATOM 6830 C CA . HIS B 1 266 ? 38.601 26.143 46.744 1.00 2.00 ? 266 HIS B CA 1 ATOM 6831 C C . HIS B 1 266 ? 38.581 25.308 48.012 1.00 3.06 ? 266 HIS B C 1 ATOM 6832 O O . HIS B 1 266 ? 37.691 25.443 48.861 1.00 2.22 ? 266 HIS B O 1 ATOM 6833 C CB . HIS B 1 266 ? 37.731 25.475 45.682 1.00 2.35 ? 266 HIS B CB 1 ATOM 6834 C CG . HIS B 1 266 ? 36.861 26.423 44.918 1.00 2.00 ? 266 HIS B CG 1 ATOM 6835 N ND1 . HIS B 1 266 ? 35.797 27.079 45.493 1.00 2.00 ? 266 HIS B ND1 1 ATOM 6836 C CD2 . HIS B 1 266 ? 36.879 26.800 43.618 1.00 2.75 ? 266 HIS B CD2 1 ATOM 6837 C CE1 . HIS B 1 266 ? 35.191 27.816 44.578 1.00 3.11 ? 266 HIS B CE1 1 ATOM 6838 N NE2 . HIS B 1 266 ? 35.828 27.664 43.431 1.00 2.41 ? 266 HIS B NE2 1 ATOM 6839 N N . THR B 1 267 ? 39.576 24.434 48.117 1.00 3.26 ? 267 THR B N 1 ATOM 6840 C CA . THR B 1 267 ? 39.723 23.559 49.263 1.00 2.18 ? 267 THR B CA 1 ATOM 6841 C C . THR B 1 267 ? 40.331 24.315 50.446 1.00 2.29 ? 267 THR B C 1 ATOM 6842 O O . THR B 1 267 ? 39.927 24.105 51.589 1.00 3.33 ? 267 THR B O 1 ATOM 6843 C CB . THR B 1 267 ? 40.565 22.337 48.876 1.00 2.61 ? 267 THR B CB 1 ATOM 6844 O OG1 . THR B 1 267 ? 39.768 21.484 48.045 1.00 2.00 ? 267 THR B OG1 1 ATOM 6845 C CG2 . THR B 1 267 ? 41.026 21.566 50.103 1.00 3.14 ? 267 THR B CG2 1 ATOM 6846 N N . LEU B 1 268 ? 41.284 25.204 50.183 1.00 2.00 ? 268 LEU B N 1 ATOM 6847 C CA . LEU B 1 268 ? 41.872 25.991 51.264 1.00 2.05 ? 268 LEU B CA 1 ATOM 6848 C C . LEU B 1 268 ? 40.807 26.916 51.879 1.00 3.27 ? 268 LEU B C 1 ATOM 6849 O O . LEU B 1 268 ? 40.671 27.001 53.104 1.00 2.00 ? 268 LEU B O 1 ATOM 6850 C CB . LEU B 1 268 ? 43.050 26.811 50.741 1.00 2.00 ? 268 LEU B CB 1 ATOM 6851 C CG . LEU B 1 268 ? 44.412 26.111 50.756 1.00 2.11 ? 268 LEU B CG 1 ATOM 6852 C CD1 . LEU B 1 268 ? 44.250 24.634 50.439 1.00 2.92 ? 268 LEU B CD1 1 ATOM 6853 C CD2 . LEU B 1 268 ? 45.339 26.787 49.750 1.00 2.22 ? 268 LEU B CD2 1 ATOM 6854 N N . LEU B 1 269 ? 40.041 27.594 51.030 1.00 3.23 ? 269 LEU B N 1 ATOM 6855 C CA . LEU B 1 269 ? 38.999 28.478 51.522 1.00 2.00 ? 269 LEU B CA 1 ATOM 6856 C C . LEU B 1 269 ? 37.950 27.696 52.297 1.00 3.91 ? 269 LEU B C 1 ATOM 6857 O O . LEU B 1 269 ? 37.510 28.130 53.360 1.00 5.39 ? 269 LEU B O 1 ATOM 6858 C CB . LEU B 1 269 ? 38.361 29.237 50.363 1.00 2.00 ? 269 LEU B CB 1 ATOM 6859 C CG . LEU B 1 269 ? 39.414 30.052 49.613 1.00 2.07 ? 269 LEU B CG 1 ATOM 6860 C CD1 . LEU B 1 269 ? 38.727 31.067 48.712 1.00 2.00 ? 269 LEU B CD1 1 ATOM 6861 C CD2 . LEU B 1 269 ? 40.338 30.770 50.608 1.00 2.00 ? 269 LEU B CD2 1 ATOM 6862 N N . LEU B 1 270 ? 37.554 26.539 51.775 1.00 3.67 ? 270 LEU B N 1 ATOM 6863 C CA . LEU B 1 270 ? 36.574 25.712 52.466 1.00 2.00 ? 270 LEU B CA 1 ATOM 6864 C C . LEU B 1 270 ? 37.171 25.312 53.792 1.00 2.00 ? 270 LEU B C 1 ATOM 6865 O O . LEU B 1 270 ? 36.516 25.373 54.822 1.00 2.00 ? 270 LEU B O 1 ATOM 6866 C CB . LEU B 1 270 ? 36.248 24.454 51.670 1.00 2.00 ? 270 LEU B CB 1 ATOM 6867 C CG . LEU B 1 270 ? 35.306 23.502 52.399 1.00 2.00 ? 270 LEU B CG 1 ATOM 6868 C CD1 . LEU B 1 270 ? 34.130 24.288 52.906 1.00 2.00 ? 270 LEU B CD1 1 ATOM 6869 C CD2 . LEU B 1 270 ? 34.845 22.397 51.478 1.00 2.00 ? 270 LEU B CD2 1 ATOM 6870 N N . ARG B 1 271 ? 38.433 24.913 53.765 1.00 2.00 ? 271 ARG B N 1 ATOM 6871 C CA . ARG B 1 271 ? 39.105 24.517 54.986 1.00 2.00 ? 271 ARG B CA 1 ATOM 6872 C C . ARG B 1 271 ? 39.219 25.647 56.015 1.00 2.00 ? 271 ARG B C 1 ATOM 6873 O O . ARG B 1 271 ? 38.981 25.421 57.198 1.00 2.03 ? 271 ARG B O 1 ATOM 6874 C CB . ARG B 1 271 ? 40.497 23.955 54.665 1.00 2.00 ? 271 ARG B CB 1 ATOM 6875 C CG . ARG B 1 271 ? 40.452 22.602 53.978 1.00 2.00 ? 271 ARG B CG 1 ATOM 6876 C CD . ARG B 1 271 ? 41.821 21.988 53.777 1.00 2.00 ? 271 ARG B CD 1 ATOM 6877 N NE . ARG B 1 271 ? 41.698 20.740 53.033 1.00 2.00 ? 271 ARG B NE 1 ATOM 6878 C CZ . ARG B 1 271 ? 42.715 19.961 52.677 1.00 2.00 ? 271 ARG B CZ 1 ATOM 6879 N NH1 . ARG B 1 271 ? 43.960 20.285 52.994 1.00 2.00 ? 271 ARG B NH1 1 ATOM 6880 N NH2 . ARG B 1 271 ? 42.481 18.852 51.994 1.00 2.05 ? 271 ARG B NH2 1 ATOM 6881 N N . GLU B 1 272 ? 39.568 26.859 55.581 1.00 2.14 ? 272 GLU B N 1 ATOM 6882 C CA . GLU B 1 272 ? 39.719 27.976 56.524 1.00 2.10 ? 272 GLU B CA 1 ATOM 6883 C C . GLU B 1 272 ? 38.427 28.315 57.249 1.00 2.00 ? 272 GLU B C 1 ATOM 6884 O O . GLU B 1 272 ? 38.446 28.865 58.355 1.00 2.00 ? 272 GLU B O 1 ATOM 6885 C CB . GLU B 1 272 ? 40.249 29.230 55.817 1.00 2.80 ? 272 GLU B CB 1 ATOM 6886 C CG . GLU B 1 272 ? 40.551 30.425 56.747 1.00 4.61 ? 272 GLU B CG 1 ATOM 6887 C CD . GLU B 1 272 ? 41.440 30.071 57.942 1.00 5.61 ? 272 GLU B CD 1 ATOM 6888 O OE1 . GLU B 1 272 ? 42.004 28.957 57.966 1.00 8.29 ? 272 GLU B OE1 1 ATOM 6889 O OE2 . GLU B 1 272 ? 41.584 30.914 58.859 1.00 6.76 ? 272 GLU B OE2 1 ATOM 6890 N N . HIS B 1 273 ? 37.301 27.998 56.622 1.00 2.02 ? 273 HIS B N 1 ATOM 6891 C CA . HIS B 1 273 ? 36.023 28.260 57.250 1.00 2.09 ? 273 HIS B CA 1 ATOM 6892 C C . HIS B 1 273 ? 35.985 27.451 58.531 1.00 3.16 ? 273 HIS B C 1 ATOM 6893 O O . HIS B 1 273 ? 35.830 27.992 59.624 1.00 3.41 ? 273 HIS B O 1 ATOM 6894 C CB . HIS B 1 273 ? 34.882 27.818 56.362 1.00 2.00 ? 273 HIS B CB 1 ATOM 6895 C CG . HIS B 1 273 ? 33.543 28.030 56.984 1.00 3.46 ? 273 HIS B CG 1 ATOM 6896 N ND1 . HIS B 1 273 ? 32.814 29.184 56.799 1.00 3.66 ? 273 HIS B ND1 1 ATOM 6897 C CD2 . HIS B 1 273 ? 32.828 27.264 57.842 1.00 4.28 ? 273 HIS B CD2 1 ATOM 6898 C CE1 . HIS B 1 273 ? 31.706 29.118 57.516 1.00 5.03 ? 273 HIS B CE1 1 ATOM 6899 N NE2 . HIS B 1 273 ? 31.690 27.964 58.159 1.00 3.92 ? 273 HIS B NE2 1 ATOM 6900 N N . ASN B 1 274 ? 36.146 26.143 58.403 1.00 2.00 ? 274 ASN B N 1 ATOM 6901 C CA . ASN B 1 274 ? 36.126 25.315 59.585 1.00 2.00 ? 274 ASN B CA 1 ATOM 6902 C C . ASN B 1 274 ? 37.158 25.663 60.664 1.00 2.00 ? 274 ASN B C 1 ATOM 6903 O O . ASN B 1 274 ? 36.755 25.811 61.800 1.00 3.58 ? 274 ASN B O 1 ATOM 6904 C CB . ASN B 1 274 ? 36.171 23.850 59.181 1.00 2.11 ? 274 ASN B CB 1 ATOM 6905 C CG . ASN B 1 274 ? 34.977 23.460 58.317 1.00 2.00 ? 274 ASN B CG 1 ATOM 6906 O OD1 . ASN B 1 274 ? 33.865 23.936 58.525 1.00 2.00 ? 274 ASN B OD1 1 ATOM 6907 N ND2 . ASN B 1 274 ? 35.204 22.589 57.356 1.00 2.00 ? 274 ASN B ND2 1 ATOM 6908 N N . ARG B 1 275 ? 38.458 25.819 60.375 1.00 2.00 ? 275 ARG B N 1 ATOM 6909 C CA . ARG B 1 275 ? 39.375 26.181 61.481 1.00 2.41 ? 275 ARG B CA 1 ATOM 6910 C C . ARG B 1 275 ? 38.749 27.359 62.254 1.00 2.00 ? 275 ARG B C 1 ATOM 6911 O O . ARG B 1 275 ? 38.776 27.398 63.482 1.00 2.00 ? 275 ARG B O 1 ATOM 6912 C CB . ARG B 1 275 ? 40.807 26.632 61.019 1.00 2.89 ? 275 ARG B CB 1 ATOM 6913 C CG . ARG B 1 275 ? 41.219 27.971 61.741 1.00 5.49 ? 275 ARG B CG 1 ATOM 6914 C CD . ARG B 1 275 ? 42.662 28.568 61.689 1.00 4.92 ? 275 ARG B CD 1 ATOM 6915 N NE . ARG B 1 275 ? 42.629 29.741 62.584 1.00 12.11 ? 275 ARG B NE 1 ATOM 6916 C CZ . ARG B 1 275 ? 43.661 30.488 63.005 1.00 13.66 ? 275 ARG B CZ 1 ATOM 6917 N NH1 . ARG B 1 275 ? 44.924 30.246 62.630 1.00 14.04 ? 275 ARG B NH1 1 ATOM 6918 N NH2 . ARG B 1 275 ? 43.412 31.484 63.855 1.00 14.50 ? 275 ARG B NH2 1 ATOM 6919 N N . LEU B 1 276 ? 38.184 28.312 61.516 1.00 2.00 ? 276 LEU B N 1 ATOM 6920 C CA . LEU B 1 276 ? 37.612 29.514 62.114 1.00 2.10 ? 276 LEU B CA 1 ATOM 6921 C C . LEU B 1 276 ? 36.366 29.329 62.953 1.00 2.00 ? 276 LEU B C 1 ATOM 6922 O O . LEU B 1 276 ? 36.230 29.955 64.002 1.00 2.00 ? 276 LEU B O 1 ATOM 6923 C CB . LEU B 1 276 ? 37.358 30.567 61.026 1.00 2.29 ? 276 LEU B CB 1 ATOM 6924 C CG . LEU B 1 276 ? 38.366 31.723 60.972 1.00 2.16 ? 276 LEU B CG 1 ATOM 6925 C CD1 . LEU B 1 276 ? 39.802 31.212 61.006 1.00 2.00 ? 276 LEU B CD1 1 ATOM 6926 C CD2 . LEU B 1 276 ? 38.109 32.520 59.716 1.00 2.00 ? 276 LEU B CD2 1 ATOM 6927 N N . ALA B 1 277 ? 35.458 28.484 62.484 1.00 2.29 ? 277 ALA B N 1 ATOM 6928 C CA . ALA B 1 277 ? 34.223 28.207 63.199 1.00 2.93 ? 277 ALA B CA 1 ATOM 6929 C C . ALA B 1 277 ? 34.555 27.448 64.471 1.00 5.29 ? 277 ALA B C 1 ATOM 6930 O O . ALA B 1 277 ? 34.178 27.861 65.563 1.00 7.31 ? 277 ALA B O 1 ATOM 6931 C CB . ALA B 1 277 ? 33.319 27.388 62.346 1.00 2.38 ? 277 ALA B CB 1 ATOM 6932 N N . ARG B 1 278 ? 35.265 26.335 64.324 1.00 8.29 ? 278 ARG B N 1 ATOM 6933 C CA . ARG B 1 278 ? 35.666 25.519 65.469 1.00 10.53 ? 278 ARG B CA 1 ATOM 6934 C C . ARG B 1 278 ? 36.328 26.405 66.510 1.00 10.57 ? 278 ARG B C 1 ATOM 6935 O O . ARG B 1 278 ? 35.949 26.408 67.684 1.00 9.97 ? 278 ARG B O 1 ATOM 6936 C CB . ARG B 1 278 ? 36.644 24.432 65.026 1.00 13.47 ? 278 ARG B CB 1 ATOM 6937 C CG . ARG B 1 278 ? 36.095 23.023 65.152 1.00 19.32 ? 278 ARG B CG 1 ATOM 6938 C CD . ARG B 1 278 ? 36.963 22.061 64.372 1.00 23.82 ? 278 ARG B CD 1 ATOM 6939 N NE . ARG B 1 278 ? 36.325 21.534 63.167 1.00 28.66 ? 278 ARG B NE 1 ATOM 6940 C CZ . ARG B 1 278 ? 36.958 21.369 62.006 1.00 31.17 ? 278 ARG B CZ 1 ATOM 6941 N NH1 . ARG B 1 278 ? 38.238 21.702 61.892 1.00 32.30 ? 278 ARG B NH1 1 ATOM 6942 N NH2 . ARG B 1 278 ? 36.328 20.841 60.961 1.00 33.14 ? 278 ARG B NH2 1 ATOM 6943 N N . GLU B 1 279 ? 37.321 27.157 66.059 1.00 11.85 ? 279 GLU B N 1 ATOM 6944 C CA . GLU B 1 279 ? 38.043 28.073 66.916 1.00 12.49 ? 279 GLU B CA 1 ATOM 6945 C C . GLU B 1 279 ? 37.047 28.952 67.656 1.00 12.25 ? 279 GLU B C 1 ATOM 6946 O O . GLU B 1 279 ? 36.922 28.865 68.870 1.00 14.35 ? 279 GLU B O 1 ATOM 6947 C CB . GLU B 1 279 ? 38.964 28.953 66.080 1.00 16.00 ? 279 GLU B CB 1 ATOM 6948 C CG . GLU B 1 279 ? 40.071 29.569 66.881 1.00 19.57 ? 279 GLU B CG 1 ATOM 6949 C CD . GLU B 1 279 ? 40.872 28.511 67.600 1.00 22.00 ? 279 GLU B CD 1 ATOM 6950 O OE1 . GLU B 1 279 ? 41.409 27.610 66.912 1.00 23.80 ? 279 GLU B OE1 1 ATOM 6951 O OE2 . GLU B 1 279 ? 40.955 28.576 68.847 1.00 23.02 ? 279 GLU B OE2 1 ATOM 6952 N N . LEU B 1 280 ? 36.325 29.794 66.925 1.00 11.28 ? 280 LEU B N 1 ATOM 6953 C CA . LEU B 1 280 ? 35.358 30.684 67.561 1.00 10.15 ? 280 LEU B CA 1 ATOM 6954 C C . LEU B 1 280 ? 34.469 29.957 68.570 1.00 9.83 ? 280 LEU B C 1 ATOM 6955 O O . LEU B 1 280 ? 34.268 30.443 69.684 1.00 9.43 ? 280 LEU B O 1 ATOM 6956 C CB . LEU B 1 280 ? 34.504 31.394 66.505 1.00 6.58 ? 280 LEU B CB 1 ATOM 6957 C CG . LEU B 1 280 ? 35.285 32.280 65.534 1.00 3.26 ? 280 LEU B CG 1 ATOM 6958 C CD1 . LEU B 1 280 ? 34.290 33.012 64.689 1.00 3.08 ? 280 LEU B CD1 1 ATOM 6959 C CD2 . LEU B 1 280 ? 36.181 33.265 66.260 1.00 2.00 ? 280 LEU B CD2 1 ATOM 6960 N N . LYS B 1 281 ? 33.952 28.792 68.186 1.00 10.05 ? 281 LYS B N 1 ATOM 6961 C CA . LYS B 1 281 ? 33.105 28.002 69.075 1.00 10.76 ? 281 LYS B CA 1 ATOM 6962 C C . LYS B 1 281 ? 33.785 27.776 70.429 1.00 11.73 ? 281 LYS B C 1 ATOM 6963 O O . LYS B 1 281 ? 33.175 27.968 71.479 1.00 11.53 ? 281 LYS B O 1 ATOM 6964 C CB . LYS B 1 281 ? 32.781 26.648 68.433 1.00 9.00 ? 281 LYS B CB 1 ATOM 6965 C CG . LYS B 1 281 ? 32.820 25.468 69.403 1.00 8.40 ? 281 LYS B CG 1 ATOM 6966 C CD . LYS B 1 281 ? 31.710 25.517 70.440 1.00 6.22 ? 281 LYS B CD 1 ATOM 6967 C CE . LYS B 1 281 ? 30.394 25.031 69.866 1.00 6.03 ? 281 LYS B CE 1 ATOM 6968 N NZ . LYS B 1 281 ? 29.351 24.947 70.926 1.00 5.60 ? 281 LYS B NZ 1 ATOM 6969 N N . ARG B 1 282 ? 35.048 27.368 70.399 1.00 12.08 ? 282 ARG B N 1 ATOM 6970 C CA . ARG B 1 282 ? 35.784 27.101 71.627 1.00 13.58 ? 282 ARG B CA 1 ATOM 6971 C C . ARG B 1 282 ? 35.959 28.343 72.485 1.00 12.09 ? 282 ARG B C 1 ATOM 6972 O O . ARG B 1 282 ? 36.013 28.262 73.718 1.00 11.39 ? 282 ARG B O 1 ATOM 6973 C CB . ARG B 1 282 ? 37.173 26.548 71.308 1.00 18.64 ? 282 ARG B CB 1 ATOM 6974 C CG . ARG B 1 282 ? 38.212 27.623 70.995 1.00 24.92 ? 282 ARG B CG 1 ATOM 6975 C CD . ARG B 1 282 ? 39.608 27.091 71.205 1.00 28.80 ? 282 ARG B CD 1 ATOM 6976 N NE . ARG B 1 282 ? 39.784 25.812 70.530 1.00 34.18 ? 282 ARG B NE 1 ATOM 6977 C CZ . ARG B 1 282 ? 40.781 24.976 70.790 1.00 37.09 ? 282 ARG B CZ 1 ATOM 6978 N NH1 . ARG B 1 282 ? 41.682 25.297 71.713 1.00 39.79 ? 282 ARG B NH1 1 ATOM 6979 N NH2 . ARG B 1 282 ? 40.875 23.826 70.132 1.00 38.31 ? 282 ARG B NH2 1 ATOM 6980 N N . LEU B 1 283 ? 36.072 29.487 71.818 1.00 10.43 ? 283 LEU B N 1 ATOM 6981 C CA . LEU B 1 283 ? 36.274 30.759 72.493 1.00 9.06 ? 283 LEU B CA 1 ATOM 6982 C C . LEU B 1 283 ? 34.974 31.355 72.972 1.00 8.59 ? 283 LEU B C 1 ATOM 6983 O O . LEU B 1 283 ? 34.912 31.944 74.042 1.00 7.66 ? 283 LEU B O 1 ATOM 6984 C CB . LEU B 1 283 ? 36.958 31.747 71.559 1.00 7.23 ? 283 LEU B CB 1 ATOM 6985 C CG . LEU B 1 283 ? 38.340 32.184 72.032 1.00 6.75 ? 283 LEU B CG 1 ATOM 6986 C CD1 . LEU B 1 283 ? 38.848 33.272 71.114 1.00 7.30 ? 283 LEU B CD1 1 ATOM 6987 C CD2 . LEU B 1 283 ? 38.271 32.683 73.469 1.00 5.73 ? 283 LEU B CD2 1 ATOM 6988 N N . ASN B 1 284 ? 33.942 31.216 72.154 1.00 10.08 ? 284 ASN B N 1 ATOM 6989 C CA . ASN B 1 284 ? 32.614 31.726 72.477 1.00 12.57 ? 284 ASN B CA 1 ATOM 6990 C C . ASN B 1 284 ? 31.705 30.488 72.525 1.00 12.30 ? 284 ASN B C 1 ATOM 6991 O O . ASN B 1 284 ? 30.867 30.272 71.643 1.00 12.75 ? 284 ASN B O 1 ATOM 6992 C CB . ASN B 1 284 ? 32.154 32.710 71.386 1.00 13.37 ? 284 ASN B CB 1 ATOM 6993 C CG . ASN B 1 284 ? 33.050 33.953 71.286 1.00 14.93 ? 284 ASN B CG 1 ATOM 6994 O OD1 . ASN B 1 284 ? 34.270 33.882 71.467 1.00 14.70 ? 284 ASN B OD1 1 ATOM 6995 N ND2 . ASN B 1 284 ? 32.441 35.093 70.976 1.00 15.16 ? 284 ASN B ND2 1 ATOM 6996 N N . PRO B 1 285 ? 31.864 29.661 73.571 1.00 10.31 ? 285 PRO B N 1 ATOM 6997 C CA . PRO B 1 285 ? 31.102 28.429 73.783 1.00 10.18 ? 285 PRO B CA 1 ATOM 6998 C C . PRO B 1 285 ? 29.597 28.587 73.666 1.00 10.88 ? 285 PRO B C 1 ATOM 6999 O O . PRO B 1 285 ? 28.929 27.781 73.020 1.00 10.05 ? 285 PRO B O 1 ATOM 7000 C CB . PRO B 1 285 ? 31.531 27.997 75.181 1.00 9.69 ? 285 PRO B CB 1 ATOM 7001 C CG . PRO B 1 285 ? 32.907 28.572 75.311 1.00 9.81 ? 285 PRO B CG 1 ATOM 7002 C CD . PRO B 1 285 ? 32.706 29.945 74.743 1.00 10.01 ? 285 PRO B CD 1 ATOM 7003 N N . HIS B 1 286 ? 29.063 29.629 74.289 1.00 12.10 ? 286 HIS B N 1 ATOM 7004 C CA . HIS B 1 286 ? 27.623 29.870 74.259 1.00 13.40 ? 286 HIS B CA 1 ATOM 7005 C C . HIS B 1 286 ? 27.096 30.240 72.872 1.00 12.56 ? 286 HIS B C 1 ATOM 7006 O O . HIS B 1 286 ? 25.882 30.206 72.641 1.00 12.94 ? 286 HIS B O 1 ATOM 7007 C CB . HIS B 1 286 ? 27.264 30.986 75.231 1.00 17.12 ? 286 HIS B CB 1 ATOM 7008 C CG . HIS B 1 286 ? 28.054 32.228 75.004 1.00 20.63 ? 286 HIS B CG 1 ATOM 7009 N ND1 . HIS B 1 286 ? 29.394 32.316 75.314 1.00 22.16 ? 286 HIS B ND1 1 ATOM 7010 C CD2 . HIS B 1 286 ? 27.725 33.395 74.403 1.00 22.29 ? 286 HIS B CD2 1 ATOM 7011 C CE1 . HIS B 1 286 ? 29.858 33.485 74.910 1.00 24.81 ? 286 HIS B CE1 1 ATOM 7012 N NE2 . HIS B 1 286 ? 28.866 34.159 74.353 1.00 24.97 ? 286 HIS B NE2 1 ATOM 7013 N N . TRP B 1 287 ? 27.988 30.598 71.951 1.00 9.52 ? 287 TRP B N 1 ATOM 7014 C CA . TRP B 1 287 ? 27.538 30.970 70.618 1.00 7.02 ? 287 TRP B CA 1 ATOM 7015 C C . TRP B 1 287 ? 26.813 29.858 69.889 1.00 6.95 ? 287 TRP B C 1 ATOM 7016 O O . TRP B 1 287 ? 27.188 28.694 69.959 1.00 7.77 ? 287 TRP B O 1 ATOM 7017 C CB . TRP B 1 287 ? 28.701 31.486 69.784 1.00 6.51 ? 287 TRP B CB 1 ATOM 7018 C CG . TRP B 1 287 ? 28.837 32.953 69.918 1.00 7.46 ? 287 TRP B CG 1 ATOM 7019 C CD1 . TRP B 1 287 ? 28.117 33.756 70.747 1.00 8.65 ? 287 TRP B CD1 1 ATOM 7020 C CD2 . TRP B 1 287 ? 29.718 33.814 69.188 1.00 7.43 ? 287 TRP B CD2 1 ATOM 7021 N NE1 . TRP B 1 287 ? 28.487 35.066 70.579 1.00 10.10 ? 287 TRP B NE1 1 ATOM 7022 C CE2 . TRP B 1 287 ? 29.469 35.131 69.627 1.00 7.93 ? 287 TRP B CE2 1 ATOM 7023 C CE3 . TRP B 1 287 ? 30.691 33.603 68.205 1.00 5.99 ? 287 TRP B CE3 1 ATOM 7024 C CZ2 . TRP B 1 287 ? 30.160 36.235 69.118 1.00 7.25 ? 287 TRP B CZ2 1 ATOM 7025 C CZ3 . TRP B 1 287 ? 31.376 34.698 67.700 1.00 5.39 ? 287 TRP B CZ3 1 ATOM 7026 C CH2 . TRP B 1 287 ? 31.105 35.998 68.158 1.00 6.09 ? 287 TRP B CH2 1 ATOM 7027 N N . ASP B 1 288 ? 25.758 30.236 69.189 1.00 5.42 ? 288 ASP B N 1 ATOM 7028 C CA . ASP B 1 288 ? 24.945 29.290 68.459 1.00 4.83 ? 288 ASP B CA 1 ATOM 7029 C C . ASP B 1 288 ? 25.361 29.148 66.989 1.00 3.83 ? 288 ASP B C 1 ATOM 7030 O O . ASP B 1 288 ? 25.879 30.085 66.379 1.00 2.00 ? 288 ASP B O 1 ATOM 7031 C CB . ASP B 1 288 ? 23.489 29.728 68.589 1.00 9.57 ? 288 ASP B CB 1 ATOM 7032 C CG . ASP B 1 288 ? 22.729 29.624 67.292 1.00 13.38 ? 288 ASP B CG 1 ATOM 7033 O OD1 . ASP B 1 288 ? 22.531 28.475 66.817 1.00 15.55 ? 288 ASP B OD1 1 ATOM 7034 O OD2 . ASP B 1 288 ? 22.333 30.693 66.757 1.00 12.08 ? 288 ASP B OD2 1 ATOM 7035 N N . GLY B 1 289 ? 25.119 27.960 66.436 1.00 3.17 ? 289 GLY B N 1 ATOM 7036 C CA . GLY B 1 289 ? 25.466 27.649 65.054 1.00 2.81 ? 289 GLY B CA 1 ATOM 7037 C C . GLY B 1 289 ? 25.423 28.778 64.041 1.00 2.25 ? 289 GLY B C 1 ATOM 7038 O O . GLY B 1 289 ? 26.452 29.162 63.486 1.00 2.00 ? 289 GLY B O 1 ATOM 7039 N N . GLU B 1 290 ? 24.222 29.285 63.787 1.00 2.26 ? 290 GLU B N 1 ATOM 7040 C CA . GLU B 1 290 ? 24.000 30.379 62.853 1.00 2.00 ? 290 GLU B CA 1 ATOM 7041 C C . GLU B 1 290 ? 24.969 31.523 63.125 1.00 2.00 ? 290 GLU B C 1 ATOM 7042 O O . GLU B 1 290 ? 25.521 32.117 62.201 1.00 2.00 ? 290 GLU B O 1 ATOM 7043 C CB . GLU B 1 290 ? 22.580 30.891 63.014 1.00 2.00 ? 290 GLU B CB 1 ATOM 7044 C CG . GLU B 1 290 ? 22.159 31.883 61.970 1.00 3.12 ? 290 GLU B CG 1 ATOM 7045 C CD . GLU B 1 290 ? 22.037 31.241 60.616 1.00 5.32 ? 290 GLU B CD 1 ATOM 7046 O OE1 . GLU B 1 290 ? 21.637 30.055 60.568 1.00 6.59 ? 290 GLU B OE1 1 ATOM 7047 O OE2 . GLU B 1 290 ? 22.326 31.917 59.603 1.00 7.99 ? 290 GLU B OE2 1 ATOM 7048 N N . LYS B 1 291 ? 25.158 31.837 64.402 1.00 2.34 ? 291 LYS B N 1 ATOM 7049 C CA . LYS B 1 291 ? 26.061 32.909 64.806 1.00 2.88 ? 291 LYS B CA 1 ATOM 7050 C C . LYS B 1 291 ? 27.474 32.560 64.354 1.00 4.85 ? 291 LYS B C 1 ATOM 7051 O O . LYS B 1 291 ? 28.183 33.411 63.810 1.00 6.31 ? 291 LYS B O 1 ATOM 7052 C CB . LYS B 1 291 ? 26.012 33.081 66.326 1.00 3.04 ? 291 LYS B CB 1 ATOM 7053 C CG . LYS B 1 291 ? 27.047 34.018 66.922 1.00 2.00 ? 291 LYS B CG 1 ATOM 7054 C CD . LYS B 1 291 ? 26.701 35.477 66.723 1.00 2.00 ? 291 LYS B CD 1 ATOM 7055 C CE . LYS B 1 291 ? 26.799 36.209 68.061 1.00 2.98 ? 291 LYS B CE 1 ATOM 7056 N NZ . LYS B 1 291 ? 27.366 37.586 67.937 1.00 2.21 ? 291 LYS B NZ 1 ATOM 7057 N N . LEU B 1 292 ? 27.882 31.307 64.573 1.00 5.85 ? 292 LEU B N 1 ATOM 7058 C CA . LEU B 1 292 ? 29.220 30.856 64.158 1.00 5.74 ? 292 LEU B CA 1 ATOM 7059 C C . LEU B 1 292 ? 29.394 30.973 62.631 1.00 5.33 ? 292 LEU B C 1 ATOM 7060 O O . LEU B 1 292 ? 30.330 31.618 62.152 1.00 3.29 ? 292 LEU B O 1 ATOM 7061 C CB . LEU B 1 292 ? 29.477 29.395 64.593 1.00 4.19 ? 292 LEU B CB 1 ATOM 7062 C CG . LEU B 1 292 ? 29.777 29.032 66.056 1.00 2.00 ? 292 LEU B CG 1 ATOM 7063 C CD1 . LEU B 1 292 ? 30.945 29.855 66.594 1.00 2.00 ? 292 LEU B CD1 1 ATOM 7064 C CD2 . LEU B 1 292 ? 28.541 29.263 66.885 1.00 3.06 ? 292 LEU B CD2 1 ATOM 7065 N N . TYR B 1 293 ? 28.481 30.345 61.887 1.00 5.42 ? 293 TYR B N 1 ATOM 7066 C CA . TYR B 1 293 ? 28.482 30.355 60.422 1.00 6.77 ? 293 TYR B CA 1 ATOM 7067 C C . TYR B 1 293 ? 28.736 31.717 59.784 1.00 8.68 ? 293 TYR B C 1 ATOM 7068 O O . TYR B 1 293 ? 29.460 31.814 58.788 1.00 8.70 ? 293 TYR B O 1 ATOM 7069 C CB . TYR B 1 293 ? 27.140 29.832 59.892 1.00 7.91 ? 293 TYR B CB 1 ATOM 7070 C CG . TYR B 1 293 ? 26.929 30.036 58.400 1.00 9.22 ? 293 TYR B CG 1 ATOM 7071 C CD1 . TYR B 1 293 ? 27.697 29.342 57.463 1.00 9.44 ? 293 TYR B CD1 1 ATOM 7072 C CD2 . TYR B 1 293 ? 25.958 30.926 57.927 1.00 10.89 ? 293 TYR B CD2 1 ATOM 7073 C CE1 . TYR B 1 293 ? 27.504 29.525 56.087 1.00 10.67 ? 293 TYR B CE1 1 ATOM 7074 C CE2 . TYR B 1 293 ? 25.755 31.118 56.550 1.00 11.97 ? 293 TYR B CE2 1 ATOM 7075 C CZ . TYR B 1 293 ? 26.532 30.412 55.639 1.00 11.28 ? 293 TYR B CZ 1 ATOM 7076 O OH . TYR B 1 293 ? 26.329 30.595 54.291 1.00 10.07 ? 293 TYR B OH 1 ATOM 7077 N N . GLN B 1 294 ? 28.144 32.768 60.348 1.00 8.40 ? 294 GLN B N 1 ATOM 7078 C CA . GLN B 1 294 ? 28.298 34.089 59.764 1.00 7.83 ? 294 GLN B CA 1 ATOM 7079 C C . GLN B 1 294 ? 29.432 34.941 60.304 1.00 7.15 ? 294 GLN B C 1 ATOM 7080 O O . GLN B 1 294 ? 29.948 35.793 59.582 1.00 8.45 ? 294 GLN B O 1 ATOM 7081 C CB . GLN B 1 294 ? 26.955 34.815 59.821 1.00 7.18 ? 294 GLN B CB 1 ATOM 7082 C CG . GLN B 1 294 ? 25.886 33.945 59.180 1.00 7.27 ? 294 GLN B CG 1 ATOM 7083 C CD . GLN B 1 294 ? 24.770 34.725 58.552 1.00 8.41 ? 294 GLN B CD 1 ATOM 7084 O OE1 . GLN B 1 294 ? 23.910 35.273 59.249 1.00 10.54 ? 294 GLN B OE1 1 ATOM 7085 N NE2 . GLN B 1 294 ? 24.771 34.789 57.219 1.00 7.68 ? 294 GLN B NE2 1 ATOM 7086 N N . GLU B 1 295 ? 29.835 34.721 61.552 1.00 5.80 ? 295 GLU B N 1 ATOM 7087 C CA . GLU B 1 295 ? 30.955 35.481 62.100 1.00 4.68 ? 295 GLU B CA 1 ATOM 7088 C C . GLU B 1 295 ? 32.197 34.968 61.362 1.00 4.94 ? 295 GLU B C 1 ATOM 7089 O O . GLU B 1 295 ? 33.158 35.705 61.142 1.00 4.26 ? 295 GLU B O 1 ATOM 7090 C CB . GLU B 1 295 ? 31.081 35.251 63.610 1.00 5.51 ? 295 GLU B CB 1 ATOM 7091 C CG . GLU B 1 295 ? 30.314 36.252 64.481 1.00 6.21 ? 295 GLU B CG 1 ATOM 7092 C CD . GLU B 1 295 ? 30.876 37.667 64.396 1.00 7.96 ? 295 GLU B CD 1 ATOM 7093 O OE1 . GLU B 1 295 ? 32.112 37.807 64.256 1.00 9.80 ? 295 GLU B OE1 1 ATOM 7094 O OE2 . GLU B 1 295 ? 30.091 38.639 64.488 1.00 6.75 ? 295 GLU B OE2 1 ATOM 7095 N N . ALA B 1 296 ? 32.136 33.695 60.969 1.00 4.77 ? 296 ALA B N 1 ATOM 7096 C CA . ALA B 1 296 ? 33.195 33.014 60.218 1.00 3.40 ? 296 ALA B CA 1 ATOM 7097 C C . ALA B 1 296 ? 33.211 33.560 58.785 1.00 2.83 ? 296 ALA B C 1 ATOM 7098 O O . ALA B 1 296 ? 34.249 34.010 58.278 1.00 2.77 ? 296 ALA B O 1 ATOM 7099 C CB . ALA B 1 296 ? 32.921 31.508 60.195 1.00 2.22 ? 296 ALA B CB 1 ATOM 7100 N N . ARG B 1 297 ? 32.044 33.499 58.144 1.00 2.26 ? 297 ARG B N 1 ATOM 7101 C CA . ARG B 1 297 ? 31.848 33.997 56.783 1.00 2.96 ? 297 ARG B CA 1 ATOM 7102 C C . ARG B 1 297 ? 32.323 35.453 56.670 1.00 3.49 ? 297 ARG B C 1 ATOM 7103 O O . ARG B 1 297 ? 32.825 35.883 55.626 1.00 3.51 ? 297 ARG B O 1 ATOM 7104 C CB . ARG B 1 297 ? 30.358 33.885 56.420 1.00 2.53 ? 297 ARG B CB 1 ATOM 7105 C CG . ARG B 1 297 ? 29.907 34.641 55.174 1.00 2.37 ? 297 ARG B CG 1 ATOM 7106 C CD . ARG B 1 297 ? 28.576 34.087 54.668 1.00 2.00 ? 297 ARG B CD 1 ATOM 7107 N NE . ARG B 1 297 ? 27.986 34.904 53.609 1.00 2.42 ? 297 ARG B NE 1 ATOM 7108 C CZ . ARG B 1 297 ? 27.203 35.960 53.825 1.00 3.26 ? 297 ARG B CZ 1 ATOM 7109 N NH1 . ARG B 1 297 ? 26.913 36.328 55.068 1.00 4.09 ? 297 ARG B NH1 1 ATOM 7110 N NH2 . ARG B 1 297 ? 26.700 36.643 52.803 1.00 2.06 ? 297 ARG B NH2 1 ATOM 7111 N N . LYS B 1 298 ? 32.163 36.205 57.755 1.00 2.52 ? 298 LYS B N 1 ATOM 7112 C CA . LYS B 1 298 ? 32.580 37.591 57.775 1.00 2.00 ? 298 LYS B CA 1 ATOM 7113 C C . LYS B 1 298 ? 34.096 37.614 57.872 1.00 2.00 ? 298 LYS B C 1 ATOM 7114 O O . LYS B 1 298 ? 34.744 38.309 57.103 1.00 2.54 ? 298 LYS B O 1 ATOM 7115 C CB . LYS B 1 298 ? 31.934 38.337 58.960 1.00 3.71 ? 298 LYS B CB 1 ATOM 7116 C CG . LYS B 1 298 ? 32.055 39.875 58.892 1.00 5.02 ? 298 LYS B CG 1 ATOM 7117 C CD . LYS B 1 298 ? 30.855 40.622 59.518 1.00 4.53 ? 298 LYS B CD 1 ATOM 7118 C CE . LYS B 1 298 ? 30.992 40.880 61.022 1.00 5.03 ? 298 LYS B CE 1 ATOM 7119 N NZ . LYS B 1 298 ? 29.826 41.669 61.546 1.00 4.44 ? 298 LYS B NZ 1 ATOM 7120 N N . ILE B 1 299 ? 34.673 36.844 58.791 1.00 2.00 ? 299 ILE B N 1 ATOM 7121 C CA . ILE B 1 299 ? 36.133 36.829 58.929 1.00 2.15 ? 299 ILE B CA 1 ATOM 7122 C C . ILE B 1 299 ? 36.788 36.559 57.580 1.00 3.85 ? 299 ILE B C 1 ATOM 7123 O O . ILE B 1 299 ? 37.691 37.287 57.148 1.00 2.00 ? 299 ILE B O 1 ATOM 7124 C CB . ILE B 1 299 ? 36.635 35.715 59.863 1.00 2.04 ? 299 ILE B CB 1 ATOM 7125 C CG1 . ILE B 1 299 ? 35.952 35.787 61.222 1.00 2.99 ? 299 ILE B CG1 1 ATOM 7126 C CG2 . ILE B 1 299 ? 38.131 35.876 60.069 1.00 3.00 ? 299 ILE B CG2 1 ATOM 7127 C CD1 . ILE B 1 299 ? 36.337 36.990 62.005 1.00 2.94 ? 299 ILE B CD1 1 ATOM 7128 N N . LEU B 1 300 ? 36.310 35.493 56.937 1.00 3.60 ? 300 LEU B N 1 ATOM 7129 C CA . LEU B 1 300 ? 36.803 35.029 55.644 1.00 2.00 ? 300 LEU B CA 1 ATOM 7130 C C . LEU B 1 300 ? 36.731 36.055 54.524 1.00 2.00 ? 300 LEU B C 1 ATOM 7131 O O . LEU B 1 300 ? 37.658 36.182 53.733 1.00 2.52 ? 300 LEU B O 1 ATOM 7132 C CB . LEU B 1 300 ? 36.040 33.772 55.214 1.00 2.29 ? 300 LEU B CB 1 ATOM 7133 C CG . LEU B 1 300 ? 36.607 33.096 53.961 1.00 2.37 ? 300 LEU B CG 1 ATOM 7134 C CD1 . LEU B 1 300 ? 38.015 32.628 54.263 1.00 2.00 ? 300 LEU B CD1 1 ATOM 7135 C CD2 . LEU B 1 300 ? 35.746 31.926 53.531 1.00 2.00 ? 300 LEU B CD2 1 ATOM 7136 N N . GLY B 1 301 ? 35.622 36.775 54.441 1.00 2.00 ? 301 GLY B N 1 ATOM 7137 C CA . GLY B 1 301 ? 35.489 37.765 53.388 1.00 2.72 ? 301 GLY B CA 1 ATOM 7138 C C . GLY B 1 301 ? 36.481 38.896 53.550 1.00 2.00 ? 301 GLY B C 1 ATOM 7139 O O . GLY B 1 301 ? 37.074 39.375 52.583 1.00 2.00 ? 301 GLY B O 1 ATOM 7140 N N . ALA B 1 302 ? 36.647 39.331 54.792 1.00 2.00 ? 302 ALA B N 1 ATOM 7141 C CA . ALA B 1 302 ? 37.578 40.400 55.099 1.00 2.00 ? 302 ALA B CA 1 ATOM 7142 C C . ALA B 1 302 ? 38.894 39.946 54.500 1.00 2.00 ? 302 ALA B C 1 ATOM 7143 O O . ALA B 1 302 ? 39.642 40.714 53.913 1.00 2.00 ? 302 ALA B O 1 ATOM 7144 C CB . ALA B 1 302 ? 37.708 40.555 56.604 1.00 2.00 ? 302 ALA B CB 1 ATOM 7145 N N . PHE B 1 303 ? 39.142 38.660 54.644 1.00 2.00 ? 303 PHE B N 1 ATOM 7146 C CA . PHE B 1 303 ? 40.348 38.046 54.149 1.00 2.00 ? 303 PHE B CA 1 ATOM 7147 C C . PHE B 1 303 ? 40.514 38.234 52.637 1.00 2.00 ? 303 PHE B C 1 ATOM 7148 O O . PHE B 1 303 ? 41.515 38.779 52.187 1.00 2.02 ? 303 PHE B O 1 ATOM 7149 C CB . PHE B 1 303 ? 40.314 36.567 54.557 1.00 2.84 ? 303 PHE B CB 1 ATOM 7150 C CG . PHE B 1 303 ? 41.364 35.721 53.915 1.00 2.00 ? 303 PHE B CG 1 ATOM 7151 C CD1 . PHE B 1 303 ? 42.710 35.955 54.141 1.00 2.00 ? 303 PHE B CD1 1 ATOM 7152 C CD2 . PHE B 1 303 ? 40.997 34.669 53.090 1.00 2.00 ? 303 PHE B CD2 1 ATOM 7153 C CE1 . PHE B 1 303 ? 43.676 35.149 53.554 1.00 2.00 ? 303 PHE B CE1 1 ATOM 7154 C CE2 . PHE B 1 303 ? 41.949 33.861 52.500 1.00 2.00 ? 303 PHE B CE2 1 ATOM 7155 C CZ . PHE B 1 303 ? 43.292 34.101 52.733 1.00 2.25 ? 303 PHE B CZ 1 ATOM 7156 N N . ILE B 1 304 ? 39.527 37.820 51.853 1.00 2.00 ? 304 ILE B N 1 ATOM 7157 C CA . ILE B 1 304 ? 39.629 37.944 50.400 1.00 2.01 ? 304 ILE B CA 1 ATOM 7158 C C . ILE B 1 304 ? 39.766 39.391 49.896 1.00 2.60 ? 304 ILE B C 1 ATOM 7159 O O . ILE B 1 304 ? 40.193 39.633 48.765 1.00 2.00 ? 304 ILE B O 1 ATOM 7160 C CB . ILE B 1 304 ? 38.426 37.273 49.716 1.00 2.00 ? 304 ILE B CB 1 ATOM 7161 C CG1 . ILE B 1 304 ? 38.111 35.961 50.438 1.00 2.00 ? 304 ILE B CG1 1 ATOM 7162 C CG2 . ILE B 1 304 ? 38.729 37.039 48.251 1.00 2.00 ? 304 ILE B CG2 1 ATOM 7163 C CD1 . ILE B 1 304 ? 37.583 34.865 49.564 1.00 2.00 ? 304 ILE B CD1 1 ATOM 7164 N N . GLN B 1 305 ? 39.412 40.354 50.737 1.00 2.44 ? 305 GLN B N 1 ATOM 7165 C CA . GLN B 1 305 ? 39.511 41.753 50.350 1.00 2.00 ? 305 GLN B CA 1 ATOM 7166 C C . GLN B 1 305 ? 40.886 42.311 50.665 1.00 2.00 ? 305 GLN B C 1 ATOM 7167 O O . GLN B 1 305 ? 41.388 43.182 49.960 1.00 2.00 ? 305 GLN B O 1 ATOM 7168 C CB . GLN B 1 305 ? 38.472 42.571 51.104 1.00 2.83 ? 305 GLN B CB 1 ATOM 7169 C CG . GLN B 1 305 ? 37.153 42.687 50.369 1.00 4.20 ? 305 GLN B CG 1 ATOM 7170 C CD . GLN B 1 305 ? 35.961 42.948 51.287 1.00 2.36 ? 305 GLN B CD 1 ATOM 7171 O OE1 . GLN B 1 305 ? 35.968 43.872 52.114 1.00 3.17 ? 305 GLN B OE1 1 ATOM 7172 N NE2 . GLN B 1 305 ? 34.840 42.246 51.306 1.00 2.00 ? 305 GLN B NE2 1 ATOM 7173 N N . ILE B 1 306 ? 41.526 41.780 51.671 1.00 2.00 ? 306 ILE B N 1 ATOM 7174 C CA . ILE B 1 306 ? 42.845 42.249 52.085 1.00 2.00 ? 306 ILE B CA 1 ATOM 7175 C C . ILE B 1 306 ? 43.951 41.655 51.311 1.00 2.00 ? 306 ILE B C 1 ATOM 7176 O O . ILE B 1 306 ? 44.962 42.333 51.080 1.00 2.55 ? 306 ILE B O 1 ATOM 7177 C CB . ILE B 1 306 ? 43.174 41.825 53.512 1.00 2.00 ? 306 ILE B CB 1 ATOM 7178 C CG1 . ILE B 1 306 ? 42.147 42.304 54.536 1.00 2.49 ? 306 ILE B CG1 1 ATOM 7179 C CG2 . ILE B 1 306 ? 44.572 42.295 53.867 1.00 2.00 ? 306 ILE B CG2 1 ATOM 7180 C CD1 . ILE B 1 306 ? 42.324 41.713 55.919 1.00 2.00 ? 306 ILE B CD1 1 ATOM 7181 N N . ILE B 1 307 ? 43.816 40.417 50.939 1.00 2.00 ? 307 ILE B N 1 ATOM 7182 C CA . ILE B 1 307 ? 44.803 39.777 50.133 1.00 2.00 ? 307 ILE B CA 1 ATOM 7183 C C . ILE B 1 307 ? 44.727 40.425 48.760 1.00 2.00 ? 307 ILE B C 1 ATOM 7184 O O . ILE B 1 307 ? 45.731 40.805 48.177 1.00 2.13 ? 307 ILE B O 1 ATOM 7185 C CB . ILE B 1 307 ? 44.528 38.274 50.047 1.00 2.00 ? 307 ILE B CB 1 ATOM 7186 C CG1 . ILE B 1 307 ? 44.682 37.646 51.436 1.00 2.00 ? 307 ILE B CG1 1 ATOM 7187 C CG2 . ILE B 1 307 ? 45.471 37.607 49.045 1.00 2.00 ? 307 ILE B CG2 1 ATOM 7188 C CD1 . ILE B 1 307 ? 46.036 37.879 52.057 1.00 2.00 ? 307 ILE B CD1 1 ATOM 7189 N N . THR B 1 308 ? 43.496 40.548 48.277 1.00 2.00 ? 308 THR B N 1 ATOM 7190 C CA . THR B 1 308 ? 43.193 41.141 46.976 1.00 2.00 ? 308 THR B CA 1 ATOM 7191 C C . THR B 1 308 ? 43.587 42.609 46.767 1.00 2.00 ? 308 THR B C 1 ATOM 7192 O O . THR B 1 308 ? 44.065 42.973 45.699 1.00 2.00 ? 308 THR B O 1 ATOM 7193 C CB . THR B 1 308 ? 41.690 41.003 46.679 1.00 2.00 ? 308 THR B CB 1 ATOM 7194 O OG1 . THR B 1 308 ? 41.411 39.651 46.303 1.00 2.20 ? 308 THR B OG1 1 ATOM 7195 C CG2 . THR B 1 308 ? 41.257 41.955 45.571 1.00 2.00 ? 308 THR B CG2 1 ATOM 7196 N N . PHE B 1 309 ? 43.375 43.456 47.767 1.00 2.03 ? 309 PHE B N 1 ATOM 7197 C CA . PHE B 1 309 ? 43.703 44.865 47.618 1.00 2.00 ? 309 PHE B CA 1 ATOM 7198 C C . PHE B 1 309 ? 45.069 45.263 48.144 1.00 2.04 ? 309 PHE B C 1 ATOM 7199 O O . PHE B 1 309 ? 45.566 46.345 47.820 1.00 2.09 ? 309 PHE B O 1 ATOM 7200 C CB . PHE B 1 309 ? 42.646 45.731 48.288 1.00 2.00 ? 309 PHE B CB 1 ATOM 7201 C CG . PHE B 1 309 ? 41.487 46.067 47.402 1.00 2.00 ? 309 PHE B CG 1 ATOM 7202 C CD1 . PHE B 1 309 ? 40.566 45.096 47.027 1.00 2.16 ? 309 PHE B CD1 1 ATOM 7203 C CD2 . PHE B 1 309 ? 41.306 47.365 46.954 1.00 2.00 ? 309 PHE B CD2 1 ATOM 7204 C CE1 . PHE B 1 309 ? 39.478 45.418 46.222 1.00 2.00 ? 309 PHE B CE1 1 ATOM 7205 C CE2 . PHE B 1 309 ? 40.226 47.695 46.151 1.00 2.00 ? 309 PHE B CE2 1 ATOM 7206 C CZ . PHE B 1 309 ? 39.310 46.721 45.783 1.00 2.00 ? 309 PHE B CZ 1 ATOM 7207 N N . ARG B 1 310 ? 45.679 44.405 48.953 1.00 2.00 ? 310 ARG B N 1 ATOM 7208 C CA . ARG B 1 310 ? 46.991 44.727 49.497 1.00 2.00 ? 310 ARG B CA 1 ATOM 7209 C C . ARG B 1 310 ? 48.125 44.004 48.808 1.00 2.00 ? 310 ARG B C 1 ATOM 7210 O O . ARG B 1 310 ? 49.191 44.572 48.563 1.00 2.00 ? 310 ARG B O 1 ATOM 7211 C CB . ARG B 1 310 ? 47.080 44.378 50.976 1.00 2.11 ? 310 ARG B CB 1 ATOM 7212 C CG . ARG B 1 310 ? 48.492 44.590 51.527 1.00 2.84 ? 310 ARG B CG 1 ATOM 7213 C CD . ARG B 1 310 ? 48.672 43.961 52.882 1.00 2.00 ? 310 ARG B CD 1 ATOM 7214 N NE . ARG B 1 310 ? 48.734 42.516 52.763 1.00 2.00 ? 310 ARG B NE 1 ATOM 7215 C CZ . ARG B 1 310 ? 48.346 41.681 53.715 1.00 2.04 ? 310 ARG B CZ 1 ATOM 7216 N NH1 . ARG B 1 310 ? 47.866 42.161 54.859 1.00 2.00 ? 310 ARG B NH1 1 ATOM 7217 N NH2 . ARG B 1 310 ? 48.429 40.369 53.519 1.00 2.06 ? 310 ARG B NH2 1 ATOM 7218 N N . ASP B 1 311 ? 47.899 42.735 48.514 1.00 2.00 ? 311 ASP B N 1 ATOM 7219 C CA . ASP B 1 311 ? 48.933 41.936 47.904 1.00 2.00 ? 311 ASP B CA 1 ATOM 7220 C C . ASP B 1 311 ? 48.754 41.746 46.401 1.00 2.00 ? 311 ASP B C 1 ATOM 7221 O O . ASP B 1 311 ? 49.732 41.744 45.655 1.00 2.00 ? 311 ASP B O 1 ATOM 7222 C CB . ASP B 1 311 ? 49.024 40.591 48.640 1.00 2.73 ? 311 ASP B CB 1 ATOM 7223 C CG . ASP B 1 311 ? 49.288 40.748 50.147 1.00 3.52 ? 311 ASP B CG 1 ATOM 7224 O OD1 . ASP B 1 311 ? 49.888 41.782 50.523 1.00 5.26 ? 311 ASP B OD1 1 ATOM 7225 O OD2 . ASP B 1 311 ? 48.913 39.852 50.926 1.00 2.98 ? 311 ASP B OD2 1 ATOM 7226 N N . TYR B 1 312 ? 47.509 41.638 45.962 1.00 2.00 ? 312 TYR B N 1 ATOM 7227 C CA . TYR B 1 312 ? 47.205 41.354 44.525 1.00 2.00 ? 312 TYR B CA 1 ATOM 7228 C C . TYR B 1 312 ? 46.963 42.461 43.522 1.00 2.00 ? 312 TYR B C 1 ATOM 7229 O O . TYR B 1 312 ? 47.354 42.325 42.358 1.00 2.24 ? 312 TYR B O 1 ATOM 7230 C CB . TYR B 1 312 ? 45.926 40.528 44.420 1.00 2.00 ? 312 TYR B CB 1 ATOM 7231 C CG . TYR B 1 312 ? 45.635 40.211 42.970 1.00 2.00 ? 312 TYR B CG 1 ATOM 7232 C CD1 . TYR B 1 312 ? 46.256 39.100 42.383 1.00 2.00 ? 312 TYR B CD1 1 ATOM 7233 C CD2 . TYR B 1 312 ? 44.806 40.997 42.173 1.00 2.00 ? 312 TYR B CD2 1 ATOM 7234 C CE1 . TYR B 1 312 ? 46.045 38.783 41.073 1.00 2.00 ? 312 TYR B CE1 1 ATOM 7235 C CE2 . TYR B 1 312 ? 44.620 40.689 40.853 1.00 2.00 ? 312 TYR B CE2 1 ATOM 7236 C CZ . TYR B 1 312 ? 45.235 39.580 40.297 1.00 2.00 ? 312 TYR B CZ 1 ATOM 7237 O OH . TYR B 1 312 ? 45.055 39.288 38.958 1.00 2.00 ? 312 TYR B OH 1 ATOM 7238 N N . LEU B 1 313 ? 46.290 43.499 43.928 1.00 2.00 ? 313 LEU B N 1 ATOM 7239 C CA . LEU B 1 313 ? 46.060 44.491 42.903 1.00 2.28 ? 313 LEU B CA 1 ATOM 7240 C C . LEU B 1 313 ? 47.253 45.394 42.755 1.00 5.50 ? 313 LEU B C 1 ATOM 7241 O O . LEU B 1 313 ? 47.447 45.960 41.679 1.00 6.47 ? 313 LEU B O 1 ATOM 7242 C CB . LEU B 1 313 ? 44.825 45.315 43.225 1.00 2.00 ? 313 LEU B CB 1 ATOM 7243 C CG . LEU B 1 313 ? 43.511 44.663 42.845 1.00 2.00 ? 313 LEU B CG 1 ATOM 7244 C CD1 . LEU B 1 313 ? 42.392 45.183 43.732 1.00 2.37 ? 313 LEU B CD1 1 ATOM 7245 C CD2 . LEU B 1 313 ? 43.185 44.876 41.363 1.00 2.08 ? 313 LEU B CD2 1 ATOM 7246 N N . PRO B 1 314 ? 48.101 45.580 43.789 1.00 2.62 ? 314 PRO B N 1 ATOM 7247 C CA . PRO B 1 314 ? 49.218 46.500 43.514 1.00 2.00 ? 314 PRO B CA 1 ATOM 7248 C C . PRO B 1 314 ? 50.010 46.097 42.307 1.00 2.00 ? 314 PRO B C 1 ATOM 7249 O O . PRO B 1 314 ? 50.330 46.895 41.408 1.00 2.00 ? 314 PRO B O 1 ATOM 7250 C CB . PRO B 1 314 ? 50.064 46.422 44.770 1.00 2.00 ? 314 PRO B CB 1 ATOM 7251 C CG . PRO B 1 314 ? 48.979 46.363 45.813 1.00 2.55 ? 314 PRO B CG 1 ATOM 7252 C CD . PRO B 1 314 ? 47.723 45.834 45.175 1.00 2.00 ? 314 PRO B CD 1 ATOM 7253 N N . ILE B 1 315 ? 50.366 44.792 42.326 1.00 2.67 ? 315 ILE B N 1 ATOM 7254 C CA . ILE B 1 315 ? 51.218 44.173 41.311 1.00 2.82 ? 315 ILE B CA 1 ATOM 7255 C C . ILE B 1 315 ? 50.541 43.816 39.997 1.00 2.61 ? 315 ILE B C 1 ATOM 7256 O O . ILE B 1 315 ? 51.127 43.112 39.168 1.00 2.95 ? 315 ILE B O 1 ATOM 7257 C CB . ILE B 1 315 ? 51.884 42.933 41.937 1.00 2.54 ? 315 ILE B CB 1 ATOM 7258 C CG1 . ILE B 1 315 ? 50.885 41.828 42.277 1.00 3.03 ? 315 ILE B CG1 1 ATOM 7259 C CG2 . ILE B 1 315 ? 52.662 43.342 43.180 1.00 2.07 ? 315 ILE B CG2 1 ATOM 7260 C CD1 . ILE B 1 315 ? 51.525 40.597 42.878 1.00 2.03 ? 315 ILE B CD1 1 ATOM 7261 N N . VAL B 1 316 ? 49.316 44.281 39.762 1.00 2.00 ? 316 VAL B N 1 ATOM 7262 C CA . VAL B 1 316 ? 48.663 44.078 38.475 1.00 2.00 ? 316 VAL B CA 1 ATOM 7263 C C . VAL B 1 316 ? 48.666 45.460 37.835 1.00 2.70 ? 316 VAL B C 1 ATOM 7264 O O . VAL B 1 316 ? 49.257 45.660 36.773 1.00 3.18 ? 316 VAL B O 1 ATOM 7265 C CB . VAL B 1 316 ? 47.213 43.588 38.599 1.00 2.00 ? 316 VAL B CB 1 ATOM 7266 C CG1 . VAL B 1 316 ? 46.529 43.661 37.243 1.00 2.00 ? 316 VAL B CG1 1 ATOM 7267 C CG2 . VAL B 1 316 ? 47.196 42.153 39.095 1.00 2.32 ? 316 VAL B CG2 1 ATOM 7268 N N . LEU B 1 317 ? 48.024 46.415 38.506 1.00 2.80 ? 317 LEU B N 1 ATOM 7269 C CA . LEU B 1 317 ? 47.954 47.800 38.037 1.00 2.66 ? 317 LEU B CA 1 ATOM 7270 C C . LEU B 1 317 ? 49.292 48.510 38.196 1.00 3.04 ? 317 LEU B C 1 ATOM 7271 O O . LEU B 1 317 ? 49.524 49.565 37.609 1.00 2.00 ? 317 LEU B O 1 ATOM 7272 C CB . LEU B 1 317 ? 46.889 48.566 38.819 1.00 2.00 ? 317 LEU B CB 1 ATOM 7273 C CG . LEU B 1 317 ? 45.426 48.343 38.438 1.00 2.31 ? 317 LEU B CG 1 ATOM 7274 C CD1 . LEU B 1 317 ? 45.302 47.166 37.489 1.00 3.35 ? 317 LEU B CD1 1 ATOM 7275 C CD2 . LEU B 1 317 ? 44.607 48.113 39.701 1.00 2.56 ? 317 LEU B CD2 1 ATOM 7276 N N . GLY B 1 318 ? 50.155 47.925 39.020 1.00 6.06 ? 318 GLY B N 1 ATOM 7277 C CA . GLY B 1 318 ? 51.478 48.476 39.266 1.00 7.65 ? 318 GLY B CA 1 ATOM 7278 C C . GLY B 1 318 ? 51.563 49.929 39.695 1.00 7.89 ? 318 GLY B C 1 ATOM 7279 O O . GLY B 1 318 ? 51.095 50.312 40.763 1.00 8.79 ? 318 GLY B O 1 ATOM 7280 N N . SER B 1 319 ? 52.175 50.743 38.847 1.00 8.87 ? 319 SER B N 1 ATOM 7281 C CA . SER B 1 319 ? 52.351 52.155 39.132 1.00 9.26 ? 319 SER B CA 1 ATOM 7282 C C . SER B 1 319 ? 51.121 52.980 38.820 1.00 9.52 ? 319 SER B C 1 ATOM 7283 O O . SER B 1 319 ? 51.167 54.198 38.916 1.00 9.48 ? 319 SER B O 1 ATOM 7284 C CB . SER B 1 319 ? 53.522 52.702 38.322 1.00 10.38 ? 319 SER B CB 1 ATOM 7285 O OG . SER B 1 319 ? 53.250 52.612 36.930 1.00 10.74 ? 319 SER B OG 1 ATOM 7286 N N . GLU B 1 320 ? 50.030 52.328 38.436 1.00 11.17 ? 320 GLU B N 1 ATOM 7287 C CA . GLU B 1 320 ? 48.800 53.045 38.104 1.00 13.20 ? 320 GLU B CA 1 ATOM 7288 C C . GLU B 1 320 ? 47.699 52.898 39.158 1.00 14.07 ? 320 GLU B C 1 ATOM 7289 O O . GLU B 1 320 ? 46.551 53.271 38.912 1.00 13.72 ? 320 GLU B O 1 ATOM 7290 C CB . GLU B 1 320 ? 48.257 52.569 36.751 1.00 15.91 ? 320 GLU B CB 1 ATOM 7291 C CG . GLU B 1 320 ? 49.025 53.059 35.530 1.00 20.11 ? 320 GLU B CG 1 ATOM 7292 C CD . GLU B 1 320 ? 48.299 54.171 34.778 1.00 22.76 ? 320 GLU B CD 1 ATOM 7293 O OE1 . GLU B 1 320 ? 47.130 53.959 34.380 1.00 24.08 ? 320 GLU B OE1 1 ATOM 7294 O OE2 . GLU B 1 320 ? 48.898 55.253 34.575 1.00 24.58 ? 320 GLU B OE2 1 ATOM 7295 N N . MET B 1 321 ? 48.038 52.359 40.328 1.00 14.82 ? 321 MET B N 1 ATOM 7296 C CA . MET B 1 321 ? 47.044 52.169 41.385 1.00 13.96 ? 321 MET B CA 1 ATOM 7297 C C . MET B 1 321 ? 46.748 53.462 42.145 1.00 16.45 ? 321 MET B C 1 ATOM 7298 O O . MET B 1 321 ? 45.586 53.843 42.297 1.00 16.65 ? 321 MET B O 1 ATOM 7299 C CB . MET B 1 321 ? 47.500 51.078 42.362 1.00 12.09 ? 321 MET B CB 1 ATOM 7300 C CG . MET B 1 321 ? 46.423 50.668 43.351 1.00 10.55 ? 321 MET B CG 1 ATOM 7301 S SD . MET B 1 321 ? 46.531 48.931 43.821 1.00 10.09 ? 321 MET B SD 1 ATOM 7302 C CE . MET B 1 321 ? 45.857 48.952 45.499 1.00 9.01 ? 321 MET B CE 1 ATOM 7303 N N . GLN B 1 322 ? 47.794 54.134 42.620 1.00 17.81 ? 322 GLN B N 1 ATOM 7304 C CA . GLN B 1 322 ? 47.619 55.386 43.351 1.00 18.78 ? 322 GLN B CA 1 ATOM 7305 C C . GLN B 1 322 ? 46.717 56.316 42.543 1.00 17.32 ? 322 GLN B C 1 ATOM 7306 O O . GLN B 1 322 ? 45.912 57.065 43.094 1.00 15.32 ? 322 GLN B O 1 ATOM 7307 C CB . GLN B 1 322 ? 48.976 56.055 43.579 1.00 23.89 ? 322 GLN B CB 1 ATOM 7308 C CG . GLN B 1 322 ? 49.980 55.184 44.315 1.00 29.64 ? 322 GLN B CG 1 ATOM 7309 C CD . GLN B 1 322 ? 51.380 55.772 44.303 1.00 32.26 ? 322 GLN B CD 1 ATOM 7310 O OE1 . GLN B 1 322 ? 51.982 55.969 43.240 1.00 33.89 ? 322 GLN B OE1 1 ATOM 7311 N NE2 . GLN B 1 322 ? 51.908 56.055 45.489 1.00 34.44 ? 322 GLN B NE2 1 ATOM 7312 N N . LYS B 1 323 ? 46.858 56.245 41.227 1.00 14.49 ? 323 LYS B N 1 ATOM 7313 C CA . LYS B 1 323 ? 46.076 57.063 40.317 1.00 13.69 ? 323 LYS B CA 1 ATOM 7314 C C . LYS B 1 323 ? 44.588 56.693 40.292 1.00 14.87 ? 323 LYS B C 1 ATOM 7315 O O . LYS B 1 323 ? 43.730 57.580 40.260 1.00 15.93 ? 323 LYS B O 1 ATOM 7316 C CB . LYS B 1 323 ? 46.665 56.943 38.910 1.00 12.25 ? 323 LYS B CB 1 ATOM 7317 C CG . LYS B 1 323 ? 45.737 57.360 37.778 1.00 12.96 ? 323 LYS B CG 1 ATOM 7318 C CD . LYS B 1 323 ? 46.248 56.805 36.444 1.00 14.39 ? 323 LYS B CD 1 ATOM 7319 C CE . LYS B 1 323 ? 46.739 57.895 35.487 1.00 15.49 ? 323 LYS B CE 1 ATOM 7320 N NZ . LYS B 1 323 ? 45.610 58.731 34.953 1.00 15.75 ? 323 LYS B NZ 1 ATOM 7321 N N . TRP B 1 324 ? 44.284 55.394 40.318 1.00 14.35 ? 324 TRP B N 1 ATOM 7322 C CA . TRP B 1 324 ? 42.895 54.929 40.255 1.00 12.52 ? 324 TRP B CA 1 ATOM 7323 C C . TRP B 1 324 ? 42.235 54.459 41.548 1.00 11.55 ? 324 TRP B C 1 ATOM 7324 O O . TRP B 1 324 ? 41.024 54.597 41.702 1.00 12.24 ? 324 TRP B O 1 ATOM 7325 C CB . TRP B 1 324 ? 42.759 53.813 39.216 1.00 13.70 ? 324 TRP B CB 1 ATOM 7326 C CG . TRP B 1 324 ? 43.033 54.252 37.819 1.00 14.06 ? 324 TRP B CG 1 ATOM 7327 C CD1 . TRP B 1 324 ? 44.194 54.091 37.119 1.00 14.40 ? 324 TRP B CD1 1 ATOM 7328 C CD2 . TRP B 1 324 ? 42.139 54.963 36.959 1.00 14.15 ? 324 TRP B CD2 1 ATOM 7329 N NE1 . TRP B 1 324 ? 44.081 54.662 35.873 1.00 15.27 ? 324 TRP B NE1 1 ATOM 7330 C CE2 . TRP B 1 324 ? 42.830 55.206 35.747 1.00 14.95 ? 324 TRP B CE2 1 ATOM 7331 C CE3 . TRP B 1 324 ? 40.822 55.421 37.094 1.00 13.66 ? 324 TRP B CE3 1 ATOM 7332 C CZ2 . TRP B 1 324 ? 42.245 55.887 34.673 1.00 14.63 ? 324 TRP B CZ2 1 ATOM 7333 C CZ3 . TRP B 1 324 ? 40.239 56.097 36.029 1.00 13.95 ? 324 TRP B CZ3 1 ATOM 7334 C CH2 . TRP B 1 324 ? 40.953 56.324 34.831 1.00 14.98 ? 324 TRP B CH2 1 ATOM 7335 N N . ILE B 1 325 ? 42.998 53.883 42.466 1.00 9.62 ? 325 ILE B N 1 ATOM 7336 C CA . ILE B 1 325 ? 42.398 53.423 43.705 1.00 8.75 ? 325 ILE B CA 1 ATOM 7337 C C . ILE B 1 325 ? 42.914 54.256 44.861 1.00 9.16 ? 325 ILE B C 1 ATOM 7338 O O . ILE B 1 325 ? 43.666 53.772 45.715 1.00 8.64 ? 325 ILE B O 1 ATOM 7339 C CB . ILE B 1 325 ? 42.697 51.927 43.991 1.00 7.71 ? 325 ILE B CB 1 ATOM 7340 C CG1 . ILE B 1 325 ? 42.305 51.061 42.794 1.00 5.84 ? 325 ILE B CG1 1 ATOM 7341 C CG2 . ILE B 1 325 ? 41.888 51.461 45.192 1.00 8.58 ? 325 ILE B CG2 1 ATOM 7342 C CD1 . ILE B 1 325 ? 42.402 49.580 43.066 1.00 2.18 ? 325 ILE B CD1 1 ATOM 7343 N N . PRO B 1 326 ? 42.523 55.537 44.900 1.00 9.95 ? 326 PRO B N 1 ATOM 7344 C CA . PRO B 1 326 ? 42.976 56.399 45.989 1.00 11.62 ? 326 PRO B CA 1 ATOM 7345 C C . PRO B 1 326 ? 42.770 55.696 47.320 1.00 11.95 ? 326 PRO B C 1 ATOM 7346 O O . PRO B 1 326 ? 41.954 54.783 47.432 1.00 10.97 ? 326 PRO B O 1 ATOM 7347 C CB . PRO B 1 326 ? 42.096 57.643 45.838 1.00 10.58 ? 326 PRO B CB 1 ATOM 7348 C CG . PRO B 1 326 ? 40.868 57.118 45.145 1.00 10.57 ? 326 PRO B CG 1 ATOM 7349 C CD . PRO B 1 326 ? 41.472 56.202 44.117 1.00 10.12 ? 326 PRO B CD 1 ATOM 7350 N N . ARG B 1 327 ? 43.524 56.125 48.320 1.00 14.77 ? 327 ARG B N 1 ATOM 7351 C CA . ARG B 1 327 ? 43.440 55.551 49.653 1.00 17.41 ? 327 ARG B CA 1 ATOM 7352 C C . ARG B 1 327 ? 42.002 55.687 50.203 1.00 15.87 ? 327 ARG B C 1 ATOM 7353 O O . ARG B 1 327 ? 41.406 56.764 50.143 1.00 15.00 ? 327 ARG B O 1 ATOM 7354 C CB . ARG B 1 327 ? 44.482 56.245 50.548 1.00 21.81 ? 327 ARG B CB 1 ATOM 7355 C CG . ARG B 1 327 ? 45.947 56.125 50.016 1.00 28.63 ? 327 ARG B CG 1 ATOM 7356 C CD . ARG B 1 327 ? 46.186 56.902 48.693 1.00 31.81 ? 327 ARG B CD 1 ATOM 7357 N NE . ARG B 1 327 ? 47.420 56.540 47.974 1.00 36.53 ? 327 ARG B NE 1 ATOM 7358 C CZ . ARG B 1 327 ? 48.647 56.992 48.255 1.00 38.06 ? 327 ARG B CZ 1 ATOM 7359 N NH1 . ARG B 1 327 ? 48.846 57.844 49.258 1.00 38.87 ? 327 ARG B NH1 1 ATOM 7360 N NH2 . ARG B 1 327 ? 49.682 56.599 47.514 1.00 38.51 ? 327 ARG B NH2 1 ATOM 7361 N N . TYR B 1 328 ? 41.453 54.584 50.719 1.00 13.74 ? 328 TYR B N 1 ATOM 7362 C CA . TYR B 1 328 ? 40.077 54.531 51.249 1.00 12.15 ? 328 TYR B CA 1 ATOM 7363 C C . TYR B 1 328 ? 39.683 55.650 52.215 1.00 12.49 ? 328 TYR B C 1 ATOM 7364 O O . TYR B 1 328 ? 40.469 56.048 53.079 1.00 10.82 ? 328 TYR B O 1 ATOM 7365 C CB . TYR B 1 328 ? 39.836 53.174 51.923 1.00 10.89 ? 328 TYR B CB 1 ATOM 7366 C CG . TYR B 1 328 ? 38.402 52.896 52.351 1.00 8.37 ? 328 TYR B CG 1 ATOM 7367 C CD1 . TYR B 1 328 ? 37.369 52.854 51.413 1.00 7.13 ? 328 TYR B CD1 1 ATOM 7368 C CD2 . TYR B 1 328 ? 38.091 52.610 53.691 1.00 6.81 ? 328 TYR B CD2 1 ATOM 7369 C CE1 . TYR B 1 328 ? 36.060 52.529 51.793 1.00 6.18 ? 328 TYR B CE1 1 ATOM 7370 C CE2 . TYR B 1 328 ? 36.785 52.283 54.082 1.00 4.88 ? 328 TYR B CE2 1 ATOM 7371 C CZ . TYR B 1 328 ? 35.773 52.242 53.124 1.00 5.63 ? 328 TYR B CZ 1 ATOM 7372 O OH . TYR B 1 328 ? 34.483 51.889 53.469 1.00 2.65 ? 328 TYR B OH 1 ATOM 7373 N N . GLN B 1 329 ? 38.443 56.128 52.074 1.00 13.62 ? 329 GLN B N 1 ATOM 7374 C CA . GLN B 1 329 ? 37.920 57.211 52.906 1.00 13.17 ? 329 GLN B CA 1 ATOM 7375 C C . GLN B 1 329 ? 36.423 57.131 53.230 1.00 11.52 ? 329 GLN B C 1 ATOM 7376 O O . GLN B 1 329 ? 35.714 58.138 53.161 1.00 10.41 ? 329 GLN B O 1 ATOM 7377 C CB . GLN B 1 329 ? 38.226 58.553 52.236 1.00 16.16 ? 329 GLN B CB 1 ATOM 7378 C CG . GLN B 1 329 ? 38.759 59.600 53.202 1.00 19.13 ? 329 GLN B CG 1 ATOM 7379 C CD . GLN B 1 329 ? 39.541 60.706 52.512 1.00 19.96 ? 329 GLN B CD 1 ATOM 7380 O OE1 . GLN B 1 329 ? 40.162 61.540 53.179 1.00 21.13 ? 329 GLN B OE1 1 ATOM 7381 N NE2 . GLN B 1 329 ? 39.513 60.723 51.176 1.00 19.31 ? 329 GLN B NE2 1 ATOM 7382 N N . GLY B 1 330 ? 35.952 55.934 53.640 1.00 10.00 ? 330 GLY B N 1 ATOM 7383 C CA . GLY B 1 330 ? 34.493 55.750 54.058 1.00 8.94 ? 330 GLY B CA 1 ATOM 7384 C C . GLY B 1 330 ? 33.370 55.334 53.023 1.00 8.81 ? 330 GLY B C 1 ATOM 7385 O O . GLY B 1 330 ? 33.528 55.588 51.821 1.00 7.45 ? 330 GLY B O 1 ATOM 7386 N N . TYR B 1 331 ? 32.204 54.693 53.513 1.00 9.22 ? 331 TYR B N 1 ATOM 7387 C CA . TYR B 1 331 ? 31.095 54.270 52.612 1.00 9.35 ? 331 TYR B CA 1 ATOM 7388 C C . TYR B 1 331 ? 30.505 55.479 51.816 1.00 10.32 ? 331 TYR B C 1 ATOM 7389 O O . TYR B 1 331 ? 29.896 56.385 52.373 1.00 10.64 ? 331 TYR B O 1 ATOM 7390 C CB . TYR B 1 331 ? 29.984 53.486 53.361 1.00 10.95 ? 331 TYR B CB 1 ATOM 7391 C CG . TYR B 1 331 ? 28.773 52.927 52.572 1.00 12.25 ? 331 TYR B CG 1 ATOM 7392 C CD1 . TYR B 1 331 ? 28.941 52.173 51.395 1.00 12.91 ? 331 TYR B CD1 1 ATOM 7393 C CD2 . TYR B 1 331 ? 27.481 53.162 53.035 1.00 12.51 ? 331 TYR B CD2 1 ATOM 7394 C CE1 . TYR B 1 331 ? 27.826 51.689 50.696 1.00 13.15 ? 331 TYR B CE1 1 ATOM 7395 C CE2 . TYR B 1 331 ? 26.389 52.680 52.344 1.00 11.95 ? 331 TYR B CE2 1 ATOM 7396 C CZ . TYR B 1 331 ? 26.559 51.957 51.177 1.00 12.35 ? 331 TYR B CZ 1 ATOM 7397 O OH . TYR B 1 331 ? 25.469 51.509 50.491 1.00 13.94 ? 331 TYR B OH 1 ATOM 7398 N N . ASN B 1 332 ? 30.727 55.430 50.516 1.00 12.43 ? 332 ASN B N 1 ATOM 7399 C CA . ASN B 1 332 ? 30.129 56.433 49.642 1.00 13.36 ? 332 ASN B CA 1 ATOM 7400 C C . ASN B 1 332 ? 28.826 55.901 49.109 1.00 11.54 ? 332 ASN B C 1 ATOM 7401 O O . ASN B 1 332 ? 28.722 55.390 47.992 1.00 9.10 ? 332 ASN B O 1 ATOM 7402 C CB . ASN B 1 332 ? 30.999 56.831 48.452 1.00 17.60 ? 332 ASN B CB 1 ATOM 7403 C CG . ASN B 1 332 ? 30.340 57.997 47.740 1.00 26.43 ? 332 ASN B CG 1 ATOM 7404 O OD1 . ASN B 1 332 ? 29.126 58.144 47.801 1.00 22.10 ? 332 ASN B OD1 1 ATOM 7405 N ND2 . ASN B 1 332 ? 31.136 58.831 47.077 1.00 38.39 ? 332 ASN B ND2 1 ATOM 7406 N N . ASN B 1 333 ? 27.842 56.035 49.956 1.00 10.05 ? 333 ASN B N 1 ATOM 7407 C CA . ASN B 1 333 ? 26.507 55.495 49.704 1.00 9.32 ? 333 ASN B CA 1 ATOM 7408 C C . ASN B 1 333 ? 26.086 55.652 48.236 1.00 7.72 ? 333 ASN B C 1 ATOM 7409 O O . ASN B 1 333 ? 25.276 54.850 47.751 1.00 6.75 ? 333 ASN B O 1 ATOM 7410 C CB . ASN B 1 333 ? 25.574 56.071 50.872 1.00 11.52 ? 333 ASN B CB 1 ATOM 7411 C CG . ASN B 1 333 ? 24.303 56.878 50.609 1.00 13.04 ? 333 ASN B CG 1 ATOM 7412 O OD1 . ASN B 1 333 ? 23.307 56.316 50.166 1.00 15.50 ? 333 ASN B OD1 1 ATOM 7413 N ND2 . ASN B 1 333 ? 24.351 58.180 50.870 1.00 12.62 ? 333 ASN B ND2 1 ATOM 7414 N N . SER B 1 334 ? 26.631 56.637 47.554 1.00 6.37 ? 334 SER B N 1 ATOM 7415 C CA . SER B 1 334 ? 26.216 56.868 46.183 1.00 5.59 ? 334 SER B CA 1 ATOM 7416 C C . SER B 1 334 ? 27.203 56.486 45.112 1.00 5.94 ? 334 SER B C 1 ATOM 7417 O O . SER B 1 334 ? 27.557 57.334 44.290 1.00 7.02 ? 334 SER B O 1 ATOM 7418 C CB . SER B 1 334 ? 25.841 58.344 46.016 1.00 5.64 ? 334 SER B CB 1 ATOM 7419 O OG . SER B 1 334 ? 24.984 58.773 47.059 1.00 9.63 ? 334 SER B OG 1 ATOM 7420 N N . VAL B 1 335 ? 27.653 55.230 45.090 1.00 4.84 ? 335 VAL B N 1 ATOM 7421 C CA . VAL B 1 335 ? 28.589 54.770 44.059 1.00 2.35 ? 335 VAL B CA 1 ATOM 7422 C C . VAL B 1 335 ? 28.186 53.394 43.530 1.00 2.00 ? 335 VAL B C 1 ATOM 7423 O O . VAL B 1 335 ? 28.006 52.460 44.302 1.00 2.00 ? 335 VAL B O 1 ATOM 7424 C CB . VAL B 1 335 ? 30.015 54.677 44.602 1.00 2.00 ? 335 VAL B CB 1 ATOM 7425 C CG1 . VAL B 1 335 ? 30.970 54.162 43.541 1.00 4.04 ? 335 VAL B CG1 1 ATOM 7426 C CG2 . VAL B 1 335 ? 30.468 56.034 45.116 1.00 2.00 ? 335 VAL B CG2 1 ATOM 7427 N N . ASP B 1 336 ? 28.025 53.274 42.216 1.00 2.62 ? 336 ASP B N 1 ATOM 7428 C CA . ASP B 1 336 ? 27.612 52.013 41.577 1.00 2.87 ? 336 ASP B CA 1 ATOM 7429 C C . ASP B 1 336 ? 28.531 50.816 41.910 1.00 2.26 ? 336 ASP B C 1 ATOM 7430 O O . ASP B 1 336 ? 29.580 50.628 41.289 1.00 2.00 ? 336 ASP B O 1 ATOM 7431 C CB . ASP B 1 336 ? 27.557 52.215 40.057 1.00 3.08 ? 336 ASP B CB 1 ATOM 7432 C CG . ASP B 1 336 ? 26.476 51.384 39.394 1.00 3.15 ? 336 ASP B CG 1 ATOM 7433 O OD1 . ASP B 1 336 ? 26.051 50.379 39.995 1.00 3.15 ? 336 ASP B OD1 1 ATOM 7434 O OD2 . ASP B 1 336 ? 26.061 51.729 38.269 1.00 2.29 ? 336 ASP B OD2 1 ATOM 7435 N N . PRO B 1 337 ? 28.125 49.968 42.869 1.00 2.72 ? 337 PRO B N 1 ATOM 7436 C CA . PRO B 1 337 ? 28.952 48.819 43.240 1.00 2.55 ? 337 PRO B CA 1 ATOM 7437 C C . PRO B 1 337 ? 28.795 47.664 42.268 1.00 3.07 ? 337 PRO B C 1 ATOM 7438 O O . PRO B 1 337 ? 29.297 46.568 42.508 1.00 4.16 ? 337 PRO B O 1 ATOM 7439 C CB . PRO B 1 337 ? 28.430 48.469 44.623 1.00 2.00 ? 337 PRO B CB 1 ATOM 7440 C CG . PRO B 1 337 ? 26.948 48.636 44.422 1.00 2.00 ? 337 PRO B CG 1 ATOM 7441 C CD . PRO B 1 337 ? 26.835 49.927 43.586 1.00 2.38 ? 337 PRO B CD 1 ATOM 7442 N N . ARG B 1 338 ? 28.101 47.912 41.167 1.00 2.00 ? 338 ARG B N 1 ATOM 7443 C CA . ARG B 1 338 ? 27.873 46.871 40.179 1.00 2.95 ? 338 ARG B CA 1 ATOM 7444 C C . ARG B 1 338 ? 29.042 46.660 39.220 1.00 2.35 ? 338 ARG B C 1 ATOM 7445 O O . ARG B 1 338 ? 29.870 47.549 39.021 1.00 3.04 ? 338 ARG B O 1 ATOM 7446 C CB . ARG B 1 338 ? 26.618 47.196 39.374 1.00 4.29 ? 338 ARG B CB 1 ATOM 7447 C CG . ARG B 1 338 ? 25.318 47.140 40.168 1.00 5.47 ? 338 ARG B CG 1 ATOM 7448 C CD . ARG B 1 338 ? 24.160 47.590 39.294 1.00 4.57 ? 338 ARG B CD 1 ATOM 7449 N NE . ARG B 1 338 ? 24.416 48.915 38.742 1.00 3.67 ? 338 ARG B NE 1 ATOM 7450 C CZ . ARG B 1 338 ? 23.889 49.360 37.613 1.00 2.75 ? 338 ARG B CZ 1 ATOM 7451 N NH1 . ARG B 1 338 ? 23.076 48.585 36.916 1.00 5.31 ? 338 ARG B NH1 1 ATOM 7452 N NH2 . ARG B 1 338 ? 24.183 50.571 37.176 1.00 4.79 ? 338 ARG B NH2 1 ATOM 7453 N N . ILE B 1 339 ? 29.097 45.472 38.627 1.00 2.00 ? 339 ILE B N 1 ATOM 7454 C CA . ILE B 1 339 ? 30.143 45.142 37.667 1.00 3.84 ? 339 ILE B CA 1 ATOM 7455 C C . ILE B 1 339 ? 29.676 45.521 36.262 1.00 2.00 ? 339 ILE B C 1 ATOM 7456 O O . ILE B 1 339 ? 28.585 45.147 35.842 1.00 2.00 ? 339 ILE B O 1 ATOM 7457 C CB . ILE B 1 339 ? 30.465 43.626 37.661 1.00 2.57 ? 339 ILE B CB 1 ATOM 7458 C CG1 . ILE B 1 339 ? 30.956 43.167 39.041 1.00 2.00 ? 339 ILE B CG1 1 ATOM 7459 C CG2 . ILE B 1 339 ? 31.496 43.333 36.582 1.00 2.00 ? 339 ILE B CG2 1 ATOM 7460 C CD1 . ILE B 1 339 ? 32.415 43.431 39.300 1.00 2.00 ? 339 ILE B CD1 1 ATOM 7461 N N . SER B 1 340 ? 30.507 46.262 35.542 1.00 2.00 ? 340 SER B N 1 ATOM 7462 C CA . SER B 1 340 ? 30.186 46.675 34.183 1.00 2.12 ? 340 SER B CA 1 ATOM 7463 C C . SER B 1 340 ? 30.409 45.492 33.235 1.00 3.56 ? 340 SER B C 1 ATOM 7464 O O . SER B 1 340 ? 31.156 44.569 33.569 1.00 6.08 ? 340 SER B O 1 ATOM 7465 C CB . SER B 1 340 ? 31.076 47.850 33.793 1.00 2.00 ? 340 SER B CB 1 ATOM 7466 O OG . SER B 1 340 ? 32.409 47.630 34.220 1.00 2.00 ? 340 SER B OG 1 ATOM 7467 N N . ASN B 1 341 ? 29.770 45.507 32.064 1.00 2.34 ? 341 ASN B N 1 ATOM 7468 C CA . ASN B 1 341 ? 29.922 44.406 31.111 1.00 2.00 ? 341 ASN B CA 1 ATOM 7469 C C . ASN B 1 341 ? 31.385 44.257 30.736 1.00 2.00 ? 341 ASN B C 1 ATOM 7470 O O . ASN B 1 341 ? 31.944 43.174 30.801 1.00 2.03 ? 341 ASN B O 1 ATOM 7471 C CB . ASN B 1 341 ? 29.097 44.659 29.843 1.00 2.04 ? 341 ASN B CB 1 ATOM 7472 C CG . ASN B 1 341 ? 28.490 43.383 29.265 1.00 2.00 ? 341 ASN B CG 1 ATOM 7473 O OD1 . ASN B 1 341 ? 29.189 42.394 29.036 1.00 2.00 ? 341 ASN B OD1 1 ATOM 7474 N ND2 . ASN B 1 341 ? 27.181 43.409 29.019 1.00 2.00 ? 341 ASN B ND2 1 ATOM 7475 N N . VAL B 1 342 ? 32.002 45.364 30.362 1.00 2.00 ? 342 VAL B N 1 ATOM 7476 C CA . VAL B 1 342 ? 33.396 45.366 29.962 1.00 2.00 ? 342 VAL B CA 1 ATOM 7477 C C . VAL B 1 342 ? 34.333 44.741 30.975 1.00 2.00 ? 342 VAL B C 1 ATOM 7478 O O . VAL B 1 342 ? 35.265 44.036 30.603 1.00 2.00 ? 342 VAL B O 1 ATOM 7479 C CB . VAL B 1 342 ? 33.882 46.791 29.684 1.00 2.00 ? 342 VAL B CB 1 ATOM 7480 C CG1 . VAL B 1 342 ? 33.849 47.594 30.960 1.00 2.31 ? 342 VAL B CG1 1 ATOM 7481 C CG2 . VAL B 1 342 ? 35.274 46.765 29.082 1.00 2.00 ? 342 VAL B CG2 1 ATOM 7482 N N . PHE B 1 343 ? 34.100 44.987 32.256 1.00 2.82 ? 343 PHE B N 1 ATOM 7483 C CA . PHE B 1 343 ? 34.992 44.432 33.269 1.00 2.24 ? 343 PHE B CA 1 ATOM 7484 C C . PHE B 1 343 ? 35.242 42.965 33.035 1.00 2.00 ? 343 PHE B C 1 ATOM 7485 O O . PHE B 1 343 ? 36.382 42.521 33.067 1.00 2.29 ? 343 PHE B O 1 ATOM 7486 C CB . PHE B 1 343 ? 34.426 44.600 34.673 1.00 2.00 ? 343 PHE B CB 1 ATOM 7487 C CG . PHE B 1 343 ? 35.360 44.136 35.747 1.00 2.00 ? 343 PHE B CG 1 ATOM 7488 C CD1 . PHE B 1 343 ? 36.547 44.813 35.987 1.00 2.00 ? 343 PHE B CD1 1 ATOM 7489 C CD2 . PHE B 1 343 ? 35.057 43.019 36.518 1.00 2.36 ? 343 PHE B CD2 1 ATOM 7490 C CE1 . PHE B 1 343 ? 37.423 44.388 36.984 1.00 2.46 ? 343 PHE B CE1 1 ATOM 7491 C CE2 . PHE B 1 343 ? 35.924 42.579 37.518 1.00 2.00 ? 343 PHE B CE2 1 ATOM 7492 C CZ . PHE B 1 343 ? 37.112 43.268 37.752 1.00 2.75 ? 343 PHE B CZ 1 ATOM 7493 N N . THR B 1 344 ? 34.165 42.224 32.787 1.00 2.85 ? 344 THR B N 1 ATOM 7494 C CA . THR B 1 344 ? 34.248 40.782 32.557 1.00 6.56 ? 344 THR B CA 1 ATOM 7495 C C . THR B 1 344 ? 34.991 40.390 31.268 1.00 2.34 ? 344 THR B C 1 ATOM 7496 O O . THR B 1 344 ? 35.157 39.204 30.965 1.00 2.61 ? 344 THR B O 1 ATOM 7497 C CB . THR B 1 344 ? 32.826 40.139 32.589 1.00 3.65 ? 344 THR B CB 1 ATOM 7498 O OG1 . THR B 1 344 ? 32.212 40.192 31.292 1.00 2.00 ? 344 THR B OG1 1 ATOM 7499 C CG2 . THR B 1 344 ? 31.956 40.891 33.579 1.00 2.00 ? 344 THR B CG2 1 ATOM 7500 N N . PHE B 1 345 ? 35.427 41.385 30.505 1.00 2.00 ? 345 PHE B N 1 ATOM 7501 C CA . PHE B 1 345 ? 36.184 41.103 29.303 1.00 2.00 ? 345 PHE B CA 1 ATOM 7502 C C . PHE B 1 345 ? 37.564 41.691 29.519 1.00 3.69 ? 345 PHE B C 1 ATOM 7503 O O . PHE B 1 345 ? 38.524 41.288 28.869 1.00 6.17 ? 345 PHE B O 1 ATOM 7504 C CB . PHE B 1 345 ? 35.541 41.719 28.063 1.00 2.00 ? 345 PHE B CB 1 ATOM 7505 C CG . PHE B 1 345 ? 34.300 41.011 27.605 1.00 2.00 ? 345 PHE B CG 1 ATOM 7506 C CD1 . PHE B 1 345 ? 33.037 41.482 27.959 1.00 3.18 ? 345 PHE B CD1 1 ATOM 7507 C CD2 . PHE B 1 345 ? 34.387 39.882 26.808 1.00 2.00 ? 345 PHE B CD2 1 ATOM 7508 C CE1 . PHE B 1 345 ? 31.870 40.836 27.518 1.00 2.00 ? 345 PHE B CE1 1 ATOM 7509 C CE2 . PHE B 1 345 ? 33.228 39.227 26.362 1.00 2.12 ? 345 PHE B CE2 1 ATOM 7510 C CZ . PHE B 1 345 ? 31.969 39.708 26.718 1.00 2.00 ? 345 PHE B CZ 1 ATOM 7511 N N . ALA B 1 346 ? 37.668 42.628 30.457 1.00 3.14 ? 346 ALA B N 1 ATOM 7512 C CA . ALA B 1 346 ? 38.946 43.267 30.753 1.00 2.00 ? 346 ALA B CA 1 ATOM 7513 C C . ALA B 1 346 ? 39.738 42.506 31.792 1.00 2.00 ? 346 ALA B C 1 ATOM 7514 O O . ALA B 1 346 ? 40.937 42.690 31.907 1.00 2.00 ? 346 ALA B O 1 ATOM 7515 C CB . ALA B 1 346 ? 38.724 44.676 31.232 1.00 2.00 ? 346 ALA B CB 1 ATOM 7516 N N . PHE B 1 347 ? 39.065 41.659 32.561 1.00 2.25 ? 347 PHE B N 1 ATOM 7517 C CA . PHE B 1 347 ? 39.736 40.886 33.603 1.00 2.83 ? 347 PHE B CA 1 ATOM 7518 C C . PHE B 1 347 ? 40.106 39.527 33.050 1.00 2.00 ? 347 PHE B C 1 ATOM 7519 O O . PHE B 1 347 ? 40.424 38.610 33.795 1.00 2.10 ? 347 PHE B O 1 ATOM 7520 C CB . PHE B 1 347 ? 38.816 40.717 34.826 1.00 2.00 ? 347 PHE B CB 1 ATOM 7521 C CG . PHE B 1 347 ? 39.536 40.321 36.097 1.00 2.00 ? 347 PHE B CG 1 ATOM 7522 C CD1 . PHE B 1 347 ? 40.922 40.437 36.209 1.00 2.33 ? 347 PHE B CD1 1 ATOM 7523 C CD2 . PHE B 1 347 ? 38.824 39.868 37.190 1.00 2.00 ? 347 PHE B CD2 1 ATOM 7524 C CE1 . PHE B 1 347 ? 41.583 40.110 37.387 1.00 2.00 ? 347 PHE B CE1 1 ATOM 7525 C CE2 . PHE B 1 347 ? 39.475 39.541 38.368 1.00 2.00 ? 347 PHE B CE2 1 ATOM 7526 C CZ . PHE B 1 347 ? 40.861 39.664 38.464 1.00 2.00 ? 347 PHE B CZ 1 ATOM 7527 N N . ARG B 1 348 ? 40.073 39.398 31.735 1.00 2.00 ? 348 ARG B N 1 ATOM 7528 C CA . ARG B 1 348 ? 40.388 38.126 31.132 1.00 2.00 ? 348 ARG B CA 1 ATOM 7529 C C . ARG B 1 348 ? 41.847 38.075 30.748 1.00 2.00 ? 348 ARG B C 1 ATOM 7530 O O . ARG B 1 348 ? 42.322 37.077 30.210 1.00 2.00 ? 348 ARG B O 1 ATOM 7531 C CB . ARG B 1 348 ? 39.486 37.896 29.922 1.00 2.07 ? 348 ARG B CB 1 ATOM 7532 C CG . ARG B 1 348 ? 38.003 37.850 30.276 1.00 2.00 ? 348 ARG B CG 1 ATOM 7533 C CD . ARG B 1 348 ? 37.258 36.848 29.422 1.00 2.00 ? 348 ARG B CD 1 ATOM 7534 N NE . ARG B 1 348 ? 35.812 37.017 29.496 1.00 2.00 ? 348 ARG B NE 1 ATOM 7535 C CZ . ARG B 1 348 ? 34.943 36.265 28.830 1.00 2.00 ? 348 ARG B CZ 1 ATOM 7536 N NH1 . ARG B 1 348 ? 35.370 35.290 28.042 1.00 2.00 ? 348 ARG B NH1 1 ATOM 7537 N NH2 . ARG B 1 348 ? 33.645 36.488 28.941 1.00 2.00 ? 348 ARG B NH2 1 ATOM 7538 N N . PHE B 1 349 ? 42.562 39.154 31.052 1.00 2.00 ? 349 PHE B N 1 ATOM 7539 C CA . PHE B 1 349 ? 43.983 39.236 30.735 1.00 2.54 ? 349 PHE B CA 1 ATOM 7540 C C . PHE B 1 349 ? 44.675 37.999 31.291 1.00 2.45 ? 349 PHE B C 1 ATOM 7541 O O . PHE B 1 349 ? 45.592 37.455 30.677 1.00 2.00 ? 349 PHE B O 1 ATOM 7542 C CB . PHE B 1 349 ? 44.598 40.518 31.322 1.00 2.00 ? 349 PHE B CB 1 ATOM 7543 C CG . PHE B 1 349 ? 44.614 40.563 32.825 1.00 2.00 ? 349 PHE B CG 1 ATOM 7544 C CD1 . PHE B 1 349 ? 45.532 39.806 33.553 1.00 2.30 ? 349 PHE B CD1 1 ATOM 7545 C CD2 . PHE B 1 349 ? 43.715 41.365 33.519 1.00 2.29 ? 349 PHE B CD2 1 ATOM 7546 C CE1 . PHE B 1 349 ? 45.556 39.846 34.947 1.00 2.00 ? 349 PHE B CE1 1 ATOM 7547 C CE2 . PHE B 1 349 ? 43.731 41.413 34.920 1.00 2.73 ? 349 PHE B CE2 1 ATOM 7548 C CZ . PHE B 1 349 ? 44.654 40.651 35.634 1.00 2.00 ? 349 PHE B CZ 1 ATOM 7549 N N . GLY B 1 350 ? 44.211 37.551 32.451 1.00 2.00 ? 350 GLY B N 1 ATOM 7550 C CA . GLY B 1 350 ? 44.792 36.380 33.065 1.00 2.00 ? 350 GLY B CA 1 ATOM 7551 C C . GLY B 1 350 ? 44.952 35.261 32.061 1.00 2.11 ? 350 GLY B C 1 ATOM 7552 O O . GLY B 1 350 ? 45.973 34.570 32.063 1.00 3.48 ? 350 GLY B O 1 ATOM 7553 N N . HIS B 1 351 ? 43.962 35.080 31.189 1.00 2.44 ? 351 HIS B N 1 ATOM 7554 C CA . HIS B 1 351 ? 44.035 34.013 30.192 1.00 2.46 ? 351 HIS B CA 1 ATOM 7555 C C . HIS B 1 351 ? 45.393 33.946 29.511 1.00 2.79 ? 351 HIS B C 1 ATOM 7556 O O . HIS B 1 351 ? 45.814 32.885 29.060 1.00 2.81 ? 351 HIS B O 1 ATOM 7557 C CB . HIS B 1 351 ? 42.957 34.166 29.121 1.00 2.00 ? 351 HIS B CB 1 ATOM 7558 C CG . HIS B 1 351 ? 41.579 33.761 29.658 1.00 2.15 ? 351 HIS B CG 1 ATOM 7559 N ND1 . HIS B 1 351 ? 40.410 34.052 28.991 1.00 2.68 ? 351 HIS B ND1 1 ATOM 7560 C CD2 . HIS B 1 351 ? 41.217 33.099 30.783 1.00 2.00 ? 351 HIS B CD2 1 ATOM 7561 C CE1 . HIS B 1 351 ? 39.384 33.591 29.688 1.00 2.75 ? 351 HIS B CE1 1 ATOM 7562 N NE2 . HIS B 1 351 ? 39.848 33.009 30.778 1.00 2.00 ? 351 HIS B NE2 1 ATOM 7563 N N . MET B 1 352 ? 46.059 35.071 29.482 1.00 2.64 ? 352 MET B N 1 ATOM 7564 C CA . MET B 1 352 ? 47.340 35.087 28.831 1.00 2.00 ? 352 MET B CA 1 ATOM 7565 C C . MET B 1 352 ? 48.501 34.697 29.806 1.00 2.00 ? 352 MET B C 1 ATOM 7566 O O . MET B 1 352 ? 49.655 34.680 29.391 1.00 2.00 ? 352 MET B O 1 ATOM 7567 C CB . MET B 1 352 ? 47.486 36.416 28.072 1.00 2.38 ? 352 MET B CB 1 ATOM 7568 C CG . MET B 1 352 ? 46.634 36.425 26.799 1.00 2.69 ? 352 MET B CG 1 ATOM 7569 S SD . MET B 1 352 ? 46.720 37.976 25.876 1.00 5.62 ? 352 MET B SD 1 ATOM 7570 C CE . MET B 1 352 ? 45.000 38.206 25.431 1.00 2.00 ? 352 MET B CE 1 ATOM 7571 N N . GLU B 1 353 ? 48.195 34.394 31.055 1.00 2.00 ? 353 GLU B N 1 ATOM 7572 C CA . GLU B 1 353 ? 49.277 34.096 32.020 1.00 2.00 ? 353 GLU B CA 1 ATOM 7573 C C . GLU B 1 353 ? 49.295 32.635 32.466 1.00 2.16 ? 353 GLU B C 1 ATOM 7574 O O . GLU B 1 353 ? 50.067 32.236 33.337 1.00 2.26 ? 353 GLU B O 1 ATOM 7575 C CB . GLU B 1 353 ? 49.142 35.018 33.226 1.00 2.00 ? 353 GLU B CB 1 ATOM 7576 C CG . GLU B 1 353 ? 48.642 36.406 32.868 1.00 2.00 ? 353 GLU B CG 1 ATOM 7577 C CD . GLU B 1 353 ? 48.501 37.307 34.078 1.00 2.00 ? 353 GLU B CD 1 ATOM 7578 O OE1 . GLU B 1 353 ? 47.808 36.901 35.041 1.00 2.00 ? 353 GLU B OE1 1 ATOM 7579 O OE2 . GLU B 1 353 ? 49.077 38.411 34.058 1.00 2.49 ? 353 GLU B OE2 1 ATOM 7580 N N . VAL B 1 354 ? 48.427 31.837 31.865 1.00 2.47 ? 354 VAL B N 1 ATOM 7581 C CA . VAL B 1 354 ? 48.355 30.428 32.193 1.00 2.00 ? 354 VAL B CA 1 ATOM 7582 C C . VAL B 1 354 ? 49.436 29.656 31.481 1.00 3.43 ? 354 VAL B C 1 ATOM 7583 O O . VAL B 1 354 ? 49.479 29.635 30.248 1.00 4.04 ? 354 VAL B O 1 ATOM 7584 C CB . VAL B 1 354 ? 47.075 29.831 31.734 1.00 2.28 ? 354 VAL B CB 1 ATOM 7585 C CG1 . VAL B 1 354 ? 47.018 28.392 32.206 1.00 3.10 ? 354 VAL B CG1 1 ATOM 7586 C CG2 . VAL B 1 354 ? 45.918 30.693 32.202 1.00 2.00 ? 354 VAL B CG2 1 ATOM 7587 N N . PRO B 1 355 ? 50.299 28.975 32.242 1.00 2.00 ? 355 PRO B N 1 ATOM 7588 C CA . PRO B 1 355 ? 51.405 28.178 31.711 1.00 2.00 ? 355 PRO B CA 1 ATOM 7589 C C . PRO B 1 355 ? 50.854 26.942 31.022 1.00 2.00 ? 355 PRO B C 1 ATOM 7590 O O . PRO B 1 355 ? 49.686 26.618 31.182 1.00 2.39 ? 355 PRO B O 1 ATOM 7591 C CB . PRO B 1 355 ? 52.211 27.836 32.955 1.00 2.00 ? 355 PRO B CB 1 ATOM 7592 C CG . PRO B 1 355 ? 51.793 28.891 33.961 1.00 2.40 ? 355 PRO B CG 1 ATOM 7593 C CD . PRO B 1 355 ? 50.323 28.976 33.708 1.00 2.00 ? 355 PRO B CD 1 ATOM 7594 N N . SER B 1 356 ? 51.693 26.245 30.266 1.00 2.09 ? 356 SER B N 1 ATOM 7595 C CA . SER B 1 356 ? 51.261 25.058 29.533 1.00 2.00 ? 356 SER B CA 1 ATOM 7596 C C . SER B 1 356 ? 51.377 23.758 30.310 1.00 2.00 ? 356 SER B C 1 ATOM 7597 O O . SER B 1 356 ? 51.072 22.694 29.778 1.00 2.00 ? 356 SER B O 1 ATOM 7598 C CB . SER B 1 356 ? 52.077 24.925 28.261 1.00 2.00 ? 356 SER B CB 1 ATOM 7599 O OG . SER B 1 356 ? 53.444 24.785 28.600 1.00 3.85 ? 356 SER B OG 1 ATOM 7600 N N . THR B 1 357 ? 51.823 23.839 31.559 1.00 2.11 ? 357 THR B N 1 ATOM 7601 C CA . THR B 1 357 ? 51.977 22.649 32.383 1.00 2.00 ? 357 THR B CA 1 ATOM 7602 C C . THR B 1 357 ? 51.851 22.947 33.865 1.00 2.00 ? 357 THR B C 1 ATOM 7603 O O . THR B 1 357 ? 52.264 24.008 34.333 1.00 2.00 ? 357 THR B O 1 ATOM 7604 C CB . THR B 1 357 ? 53.352 22.027 32.208 1.00 2.47 ? 357 THR B CB 1 ATOM 7605 O OG1 . THR B 1 357 ? 54.340 22.948 32.690 1.00 3.63 ? 357 THR B OG1 1 ATOM 7606 C CG2 . THR B 1 357 ? 53.620 21.719 30.761 1.00 3.44 ? 357 THR B CG2 1 ATOM 7607 N N . VAL B 1 358 ? 51.295 21.985 34.596 1.00 2.00 ? 358 VAL B N 1 ATOM 7608 C CA . VAL B 1 358 ? 51.148 22.079 36.043 1.00 2.00 ? 358 VAL B CA 1 ATOM 7609 C C . VAL B 1 358 ? 51.994 20.962 36.660 1.00 2.00 ? 358 VAL B C 1 ATOM 7610 O O . VAL B 1 358 ? 51.890 19.801 36.266 1.00 2.00 ? 358 VAL B O 1 ATOM 7611 C CB . VAL B 1 358 ? 49.689 21.900 36.477 1.00 2.00 ? 358 VAL B CB 1 ATOM 7612 C CG1 . VAL B 1 358 ? 49.624 21.664 37.971 1.00 2.00 ? 358 VAL B CG1 1 ATOM 7613 C CG2 . VAL B 1 358 ? 48.889 23.130 36.114 1.00 2.00 ? 358 VAL B CG2 1 ATOM 7614 N N . SER B 1 359 ? 52.839 21.311 37.624 1.00 2.28 ? 359 SER B N 1 ATOM 7615 C CA . SER B 1 359 ? 53.694 20.312 38.248 1.00 2.00 ? 359 SER B CA 1 ATOM 7616 C C . SER B 1 359 ? 53.427 20.070 39.728 1.00 2.00 ? 359 SER B C 1 ATOM 7617 O O . SER B 1 359 ? 52.940 20.949 40.442 1.00 2.04 ? 359 SER B O 1 ATOM 7618 C CB . SER B 1 359 ? 55.172 20.679 38.036 1.00 2.00 ? 359 SER B CB 1 ATOM 7619 O OG . SER B 1 359 ? 55.348 22.071 37.821 1.00 3.26 ? 359 SER B OG 1 ATOM 7620 N N . ARG B 1 360 ? 53.737 18.851 40.164 1.00 2.00 ? 360 ARG B N 1 ATOM 7621 C CA . ARG B 1 360 ? 53.586 18.419 41.553 1.00 2.79 ? 360 ARG B CA 1 ATOM 7622 C C . ARG B 1 360 ? 54.971 18.223 42.203 1.00 2.81 ? 360 ARG B C 1 ATOM 7623 O O . ARG B 1 360 ? 55.777 17.419 41.726 1.00 2.95 ? 360 ARG B O 1 ATOM 7624 C CB . ARG B 1 360 ? 52.815 17.093 41.617 1.00 2.39 ? 360 ARG B CB 1 ATOM 7625 C CG . ARG B 1 360 ? 51.311 17.221 41.499 1.00 2.55 ? 360 ARG B CG 1 ATOM 7626 C CD . ARG B 1 360 ? 50.823 17.167 40.066 1.00 3.95 ? 360 ARG B CD 1 ATOM 7627 N NE . ARG B 1 360 ? 50.171 15.894 39.772 1.00 5.60 ? 360 ARG B NE 1 ATOM 7628 C CZ . ARG B 1 360 ? 50.825 14.775 39.483 1.00 7.60 ? 360 ARG B CZ 1 ATOM 7629 N NH1 . ARG B 1 360 ? 52.152 14.778 39.443 1.00 7.81 ? 360 ARG B NH1 1 ATOM 7630 N NH2 . ARG B 1 360 ? 50.157 13.650 39.244 1.00 7.95 ? 360 ARG B NH2 1 ATOM 7631 N N . LEU B 1 361 ? 55.245 18.945 43.288 1.00 2.54 ? 361 LEU B N 1 ATOM 7632 C CA . LEU B 1 361 ? 56.533 18.828 43.979 1.00 3.35 ? 361 LEU B CA 1 ATOM 7633 C C . LEU B 1 361 ? 56.387 18.000 45.251 1.00 3.15 ? 361 LEU B C 1 ATOM 7634 O O . LEU B 1 361 ? 55.343 18.017 45.891 1.00 2.00 ? 361 LEU B O 1 ATOM 7635 C CB . LEU B 1 361 ? 57.096 20.216 44.357 1.00 3.54 ? 361 LEU B CB 1 ATOM 7636 C CG . LEU B 1 361 ? 57.330 21.250 43.260 1.00 3.39 ? 361 LEU B CG 1 ATOM 7637 C CD1 . LEU B 1 361 ? 57.919 22.526 43.834 1.00 2.00 ? 361 LEU B CD1 1 ATOM 7638 C CD2 . LEU B 1 361 ? 58.223 20.682 42.174 1.00 5.52 ? 361 LEU B CD2 1 ATOM 7639 N N . ASP B 1 362 ? 57.413 17.266 45.654 1.00 3.88 ? 362 ASP B N 1 ATOM 7640 C CA . ASP B 1 362 ? 57.363 16.403 46.854 1.00 6.05 ? 362 ASP B CA 1 ATOM 7641 C C . ASP B 1 362 ? 57.997 17.124 48.025 1.00 6.26 ? 362 ASP B C 1 ATOM 7642 O O . ASP B 1 362 ? 58.747 18.069 47.804 1.00 5.87 ? 362 ASP B O 1 ATOM 7643 C CB . ASP B 1 362 ? 58.164 15.146 46.653 1.00 7.62 ? 362 ASP B CB 1 ATOM 7644 C CG . ASP B 1 362 ? 59.636 15.440 46.793 1.00 9.26 ? 362 ASP B CG 1 ATOM 7645 O OD1 . ASP B 1 362 ? 60.400 14.473 47.036 1.00 8.52 ? 362 ASP B OD1 1 ATOM 7646 O OD2 . ASP B 1 362 ? 60.021 16.615 46.668 1.00 10.45 ? 362 ASP B OD2 1 ATOM 7647 N N . GLU B 1 363 ? 57.709 16.790 49.280 1.00 6.38 ? 363 GLU B N 1 ATOM 7648 C CA . GLU B 1 363 ? 58.168 17.579 50.444 1.00 8.51 ? 363 GLU B CA 1 ATOM 7649 C C . GLU B 1 363 ? 59.402 18.552 50.369 1.00 8.98 ? 363 GLU B C 1 ATOM 7650 O O . GLU B 1 363 ? 59.427 19.543 51.112 1.00 7.71 ? 363 GLU B O 1 ATOM 7651 C CB . GLU B 1 363 ? 58.345 16.623 51.588 1.00 10.20 ? 363 GLU B CB 1 ATOM 7652 C CG . GLU B 1 363 ? 57.045 16.479 52.349 1.00 11.94 ? 363 GLU B CG 1 ATOM 7653 C CD . GLU B 1 363 ? 56.799 15.072 52.785 1.00 14.31 ? 363 GLU B CD 1 ATOM 7654 O OE1 . GLU B 1 363 ? 57.048 14.118 52.015 1.00 13.93 ? 363 GLU B OE1 1 ATOM 7655 O OE2 . GLU B 1 363 ? 56.336 14.895 53.939 1.00 15.70 ? 363 GLU B OE2 1 ATOM 7656 N N . ASN B 1 364 ? 60.383 18.319 49.515 1.00 9.43 ? 364 ASN B N 1 ATOM 7657 C CA . ASN B 1 364 ? 61.496 19.249 49.461 1.00 10.21 ? 364 ASN B CA 1 ATOM 7658 C C . ASN B 1 364 ? 61.343 20.048 48.174 1.00 9.54 ? 364 ASN B C 1 ATOM 7659 O O . ASN B 1 364 ? 62.298 20.614 47.647 1.00 10.06 ? 364 ASN B O 1 ATOM 7660 C CB . ASN B 1 364 ? 62.829 18.497 49.497 1.00 11.79 ? 364 ASN B CB 1 ATOM 7661 C CG . ASN B 1 364 ? 62.969 17.620 50.732 1.00 12.49 ? 364 ASN B CG 1 ATOM 7662 O OD1 . ASN B 1 364 ? 62.844 18.094 51.864 1.00 13.73 ? 364 ASN B OD1 1 ATOM 7663 N ND2 . ASN B 1 364 ? 63.227 16.335 50.518 1.00 11.25 ? 364 ASN B ND2 1 ATOM 7664 N N . TYR B 1 365 ? 60.114 20.079 47.674 1.00 9.11 ? 365 TYR B N 1 ATOM 7665 C CA . TYR B 1 365 ? 59.807 20.808 46.461 1.00 9.56 ? 365 TYR B CA 1 ATOM 7666 C C . TYR B 1 365 ? 60.544 20.245 45.235 1.00 10.15 ? 365 TYR B C 1 ATOM 7667 O O . TYR B 1 365 ? 60.833 20.964 44.280 1.00 10.88 ? 365 TYR B O 1 ATOM 7668 C CB . TYR B 1 365 ? 60.130 22.291 46.678 1.00 7.01 ? 365 TYR B CB 1 ATOM 7669 C CG . TYR B 1 365 ? 59.152 23.007 47.604 1.00 6.50 ? 365 TYR B CG 1 ATOM 7670 C CD1 . TYR B 1 365 ? 58.232 23.939 47.108 1.00 5.58 ? 365 TYR B CD1 1 ATOM 7671 C CD2 . TYR B 1 365 ? 59.158 22.773 48.974 1.00 6.43 ? 365 TYR B CD2 1 ATOM 7672 C CE1 . TYR B 1 365 ? 57.353 24.617 47.957 1.00 2.62 ? 365 TYR B CE1 1 ATOM 7673 C CE2 . TYR B 1 365 ? 58.280 23.452 49.828 1.00 4.91 ? 365 TYR B CE2 1 ATOM 7674 C CZ . TYR B 1 365 ? 57.389 24.368 49.310 1.00 2.30 ? 365 TYR B CZ 1 ATOM 7675 O OH . TYR B 1 365 ? 56.557 25.048 50.159 1.00 2.00 ? 365 TYR B OH 1 ATOM 7676 N N . GLN B 1 366 ? 60.839 18.950 45.267 1.00 10.85 ? 366 GLN B N 1 ATOM 7677 C CA . GLN B 1 366 ? 61.518 18.287 44.159 1.00 11.23 ? 366 GLN B CA 1 ATOM 7678 C C . GLN B 1 366 ? 60.467 17.635 43.257 1.00 11.10 ? 366 GLN B C 1 ATOM 7679 O O . GLN B 1 366 ? 59.500 17.057 43.751 1.00 9.97 ? 366 GLN B O 1 ATOM 7680 C CB . GLN B 1 366 ? 62.474 17.232 44.706 1.00 14.63 ? 366 GLN B CB 1 ATOM 7681 C CG . GLN B 1 366 ? 63.689 17.816 45.389 1.00 18.47 ? 366 GLN B CG 1 ATOM 7682 C CD . GLN B 1 366 ? 64.632 18.470 44.398 1.00 20.86 ? 366 GLN B CD 1 ATOM 7683 O OE1 . GLN B 1 366 ? 64.231 19.351 43.636 1.00 22.49 ? 366 GLN B OE1 1 ATOM 7684 N NE2 . GLN B 1 366 ? 65.892 18.038 44.399 1.00 22.75 ? 366 GLN B NE2 1 ATOM 7685 N N . PRO B 1 367 ? 60.638 17.717 41.923 1.00 10.36 ? 367 PRO B N 1 ATOM 7686 C CA . PRO B 1 367 ? 59.637 17.101 41.044 1.00 8.38 ? 367 PRO B CA 1 ATOM 7687 C C . PRO B 1 367 ? 59.458 15.627 41.411 1.00 10.82 ? 367 PRO B C 1 ATOM 7688 O O . PRO B 1 367 ? 60.316 14.799 41.115 1.00 13.59 ? 367 PRO B O 1 ATOM 7689 C CB . PRO B 1 367 ? 60.235 17.311 39.656 1.00 8.14 ? 367 PRO B CB 1 ATOM 7690 C CG . PRO B 1 367 ? 61.709 17.256 39.920 1.00 7.22 ? 367 PRO B CG 1 ATOM 7691 C CD . PRO B 1 367 ? 61.827 18.119 41.149 1.00 8.92 ? 367 PRO B CD 1 ATOM 7692 N N . ARG B 1 368 ? 58.332 15.308 42.044 1.00 10.47 ? 368 ARG B N 1 ATOM 7693 C CA . ARG B 1 368 ? 58.046 13.952 42.519 1.00 8.97 ? 368 ARG B CA 1 ATOM 7694 C C . ARG B 1 368 ? 57.493 12.916 41.562 1.00 9.72 ? 368 ARG B C 1 ATOM 7695 O O . ARG B 1 368 ? 56.407 13.079 41.012 1.00 10.52 ? 368 ARG B O 1 ATOM 7696 C CB . ARG B 1 368 ? 57.072 14.015 43.688 1.00 9.09 ? 368 ARG B CB 1 ATOM 7697 C CG . ARG B 1 368 ? 55.632 14.276 43.256 1.00 6.88 ? 368 ARG B CG 1 ATOM 7698 C CD . ARG B 1 368 ? 54.742 14.523 44.448 1.00 7.80 ? 368 ARG B CD 1 ATOM 7699 N NE . ARG B 1 368 ? 54.171 13.317 45.051 1.00 7.89 ? 368 ARG B NE 1 ATOM 7700 C CZ . ARG B 1 368 ? 53.141 12.642 44.543 1.00 8.66 ? 368 ARG B CZ 1 ATOM 7701 N NH1 . ARG B 1 368 ? 52.578 13.044 43.409 1.00 7.95 ? 368 ARG B NH1 1 ATOM 7702 N NH2 . ARG B 1 368 ? 52.631 11.601 45.196 1.00 7.71 ? 368 ARG B NH2 1 ATOM 7703 N N . GLY B 1 369 ? 58.221 11.821 41.396 1.00 10.64 ? 369 GLY B N 1 ATOM 7704 C CA . GLY B 1 369 ? 57.721 10.755 40.550 1.00 12.89 ? 369 GLY B CA 1 ATOM 7705 C C . GLY B 1 369 ? 57.936 10.856 39.056 1.00 13.03 ? 369 GLY B C 1 ATOM 7706 O O . GLY B 1 369 ? 58.535 11.807 38.559 1.00 14.22 ? 369 GLY B O 1 ATOM 7707 N N . PRO B 1 370 ? 57.440 9.861 38.309 1.00 12.83 ? 370 PRO B N 1 ATOM 7708 C CA . PRO B 1 370 ? 57.557 9.790 36.853 1.00 11.93 ? 370 PRO B CA 1 ATOM 7709 C C . PRO B 1 370 ? 56.626 10.747 36.125 1.00 10.95 ? 370 PRO B C 1 ATOM 7710 O O . PRO B 1 370 ? 56.850 11.080 34.965 1.00 10.14 ? 370 PRO B O 1 ATOM 7711 C CB . PRO B 1 370 ? 57.206 8.337 36.563 1.00 12.27 ? 370 PRO B CB 1 ATOM 7712 C CG . PRO B 1 370 ? 56.135 8.077 37.559 1.00 12.24 ? 370 PRO B CG 1 ATOM 7713 C CD . PRO B 1 370 ? 56.720 8.683 38.827 1.00 12.59 ? 370 PRO B CD 1 ATOM 7714 N N . GLU B 1 371 ? 55.581 11.197 36.803 1.00 10.43 ? 371 GLU B N 1 ATOM 7715 C CA . GLU B 1 371 ? 54.629 12.077 36.150 1.00 9.55 ? 371 GLU B CA 1 ATOM 7716 C C . GLU B 1 371 ? 54.174 13.213 37.070 1.00 8.82 ? 371 GLU B C 1 ATOM 7717 O O . GLU B 1 371 ? 52.983 13.367 37.363 1.00 8.42 ? 371 GLU B O 1 ATOM 7718 C CB . GLU B 1 371 ? 53.445 11.228 35.678 1.00 9.34 ? 371 GLU B CB 1 ATOM 7719 C CG . GLU B 1 371 ? 53.900 9.903 35.082 1.00 10.74 ? 371 GLU B CG 1 ATOM 7720 C CD . GLU B 1 371 ? 52.771 8.912 34.882 1.00 13.10 ? 371 GLU B CD 1 ATOM 7721 O OE1 . GLU B 1 371 ? 51.878 8.848 35.755 1.00 14.70 ? 371 GLU B OE1 1 ATOM 7722 O OE2 . GLU B 1 371 ? 52.788 8.183 33.864 1.00 13.48 ? 371 GLU B OE2 1 ATOM 7723 N N . ALA B 1 372 ? 55.133 14.015 37.517 1.00 6.22 ? 372 ALA B N 1 ATOM 7724 C CA . ALA B 1 372 ? 54.820 15.124 38.399 1.00 5.32 ? 372 ALA B CA 1 ATOM 7725 C C . ALA B 1 372 ? 54.464 16.327 37.568 1.00 4.28 ? 372 ALA B C 1 ATOM 7726 O O . ALA B 1 372 ? 53.721 17.210 38.009 1.00 5.80 ? 372 ALA B O 1 ATOM 7727 C CB . ALA B 1 372 ? 56.017 15.450 39.276 1.00 5.54 ? 372 ALA B CB 1 ATOM 7728 N N . GLU B 1 373 ? 54.988 16.334 36.348 1.00 3.16 ? 373 GLU B N 1 ATOM 7729 C CA . GLU B 1 373 ? 54.812 17.442 35.415 1.00 3.36 ? 373 GLU B CA 1 ATOM 7730 C C . GLU B 1 373 ? 53.779 17.196 34.324 1.00 2.00 ? 373 GLU B C 1 ATOM 7731 O O . GLU B 1 373 ? 54.125 16.683 33.270 1.00 3.08 ? 373 GLU B O 1 ATOM 7732 C CB . GLU B 1 373 ? 56.163 17.714 34.785 1.00 2.51 ? 373 GLU B CB 1 ATOM 7733 C CG . GLU B 1 373 ? 56.700 19.073 35.039 1.00 2.00 ? 373 GLU B CG 1 ATOM 7734 C CD . GLU B 1 373 ? 56.654 19.861 33.792 1.00 2.00 ? 373 GLU B CD 1 ATOM 7735 O OE1 . GLU B 1 373 ? 55.532 20.070 33.283 1.00 2.00 ? 373 GLU B OE1 1 ATOM 7736 O OE2 . GLU B 1 373 ? 57.737 20.246 33.315 1.00 2.29 ? 373 GLU B OE2 1 ATOM 7737 N N . LEU B 1 374 ? 52.528 17.590 34.547 1.00 2.00 ? 374 LEU B N 1 ATOM 7738 C CA . LEU B 1 374 ? 51.481 17.333 33.553 1.00 2.43 ? 374 LEU B CA 1 ATOM 7739 C C . LEU B 1 374 ? 51.126 18.515 32.628 1.00 3.11 ? 374 LEU B C 1 ATOM 7740 O O . LEU B 1 374 ? 51.266 19.685 32.999 1.00 3.86 ? 374 LEU B O 1 ATOM 7741 C CB . LEU B 1 374 ? 50.204 16.827 34.262 1.00 2.00 ? 374 LEU B CB 1 ATOM 7742 C CG . LEU B 1 374 ? 50.298 15.788 35.401 1.00 2.00 ? 374 LEU B CG 1 ATOM 7743 C CD1 . LEU B 1 374 ? 48.900 15.414 35.900 1.00 2.00 ? 374 LEU B CD1 1 ATOM 7744 C CD2 . LEU B 1 374 ? 51.021 14.550 34.925 1.00 2.00 ? 374 LEU B CD2 1 ATOM 7745 N N . PRO B 1 375 ? 50.520 18.156 31.478 1.00 2.03 ? 375 PRO B N 1 ATOM 7746 C CA . PRO B 1 375 ? 50.030 19.139 30.465 1.00 2.71 ? 375 PRO B CA 1 ATOM 7747 C C . PRO B 1 375 ? 48.868 19.922 30.937 1.00 2.00 ? 375 PRO B C 1 ATOM 7748 O O . PRO B 1 375 ? 47.882 19.288 31.287 1.00 2.00 ? 375 PRO B O 1 ATOM 7749 C CB . PRO B 1 375 ? 49.540 18.299 29.344 1.00 2.17 ? 375 PRO B CB 1 ATOM 7750 C CG . PRO B 1 375 ? 50.594 17.238 29.307 1.00 2.00 ? 375 PRO B CG 1 ATOM 7751 C CD . PRO B 1 375 ? 51.243 17.172 30.649 1.00 2.35 ? 375 PRO B CD 1 ATOM 7752 N N . LEU B 1 376 ? 48.859 21.234 30.968 1.00 2.07 ? 376 LEU B N 1 ATOM 7753 C CA . LEU B 1 376 ? 47.646 21.912 31.357 1.00 2.43 ? 376 LEU B CA 1 ATOM 7754 C C . LEU B 1 376 ? 46.377 21.271 30.783 1.00 2.17 ? 376 LEU B C 1 ATOM 7755 O O . LEU B 1 376 ? 45.335 21.201 31.450 1.00 2.00 ? 376 LEU B O 1 ATOM 7756 C CB . LEU B 1 376 ? 47.746 23.348 30.817 1.00 2.00 ? 376 LEU B CB 1 ATOM 7757 C CG . LEU B 1 376 ? 46.854 24.355 31.491 1.00 2.00 ? 376 LEU B CG 1 ATOM 7758 C CD1 . LEU B 1 376 ? 45.557 24.521 30.728 1.00 2.00 ? 376 LEU B CD1 1 ATOM 7759 C CD2 . LEU B 1 376 ? 46.582 23.961 32.935 1.00 2.00 ? 376 LEU B CD2 1 ATOM 7760 N N . HIS B 1 377 ? 46.473 20.827 29.552 1.00 2.68 ? 377 HIS B N 1 ATOM 7761 C CA . HIS B 1 377 ? 45.281 20.338 28.883 1.00 3.45 ? 377 HIS B CA 1 ATOM 7762 C C . HIS B 1 377 ? 44.618 19.104 29.475 1.00 2.00 ? 377 HIS B C 1 ATOM 7763 O O . HIS B 1 377 ? 43.416 18.919 29.300 1.00 2.45 ? 377 HIS B O 1 ATOM 7764 C CB . HIS B 1 377 ? 45.590 20.190 27.408 1.00 2.18 ? 377 HIS B CB 1 ATOM 7765 C CG . HIS B 1 377 ? 45.803 18.748 26.949 1.00 2.00 ? 377 HIS B CG 1 ATOM 7766 N ND1 . HIS B 1 377 ? 46.843 18.405 26.115 1.00 2.00 ? 377 HIS B ND1 1 ATOM 7767 C CD2 . HIS B 1 377 ? 45.111 17.608 27.178 1.00 2.00 ? 377 HIS B CD2 1 ATOM 7768 C CE1 . HIS B 1 377 ? 46.783 17.113 25.850 1.00 2.91 ? 377 HIS B CE1 1 ATOM 7769 N NE2 . HIS B 1 377 ? 45.741 16.605 26.483 1.00 2.00 ? 377 HIS B NE2 1 ATOM 7770 N N . THR B 1 378 ? 45.372 18.264 30.174 1.00 2.00 ? 378 THR B N 1 ATOM 7771 C CA . THR B 1 378 ? 44.770 17.067 30.758 1.00 2.44 ? 378 THR B CA 1 ATOM 7772 C C . THR B 1 378 ? 44.339 17.314 32.199 1.00 2.37 ? 378 THR B C 1 ATOM 7773 O O . THR B 1 378 ? 44.202 16.372 32.978 1.00 2.00 ? 378 THR B O 1 ATOM 7774 C CB . THR B 1 378 ? 45.744 15.872 30.746 1.00 2.00 ? 378 THR B CB 1 ATOM 7775 O OG1 . THR B 1 378 ? 46.664 15.980 31.840 1.00 2.00 ? 378 THR B OG1 1 ATOM 7776 C CG2 . THR B 1 378 ? 46.523 15.848 29.449 1.00 3.15 ? 378 THR B CG2 1 ATOM 7777 N N . LEU B 1 379 ? 44.116 18.579 32.545 1.00 2.11 ? 379 LEU B N 1 ATOM 7778 C CA . LEU B 1 379 ? 43.726 18.940 33.904 1.00 2.00 ? 379 LEU B CA 1 ATOM 7779 C C . LEU B 1 379 ? 42.383 19.674 34.057 1.00 2.61 ? 379 LEU B C 1 ATOM 7780 O O . LEU B 1 379 ? 42.003 19.999 35.180 1.00 2.01 ? 379 LEU B O 1 ATOM 7781 C CB . LEU B 1 379 ? 44.834 19.776 34.553 1.00 2.00 ? 379 LEU B CB 1 ATOM 7782 C CG . LEU B 1 379 ? 46.190 19.113 34.795 1.00 2.00 ? 379 LEU B CG 1 ATOM 7783 C CD1 . LEU B 1 379 ? 47.186 20.175 35.181 1.00 2.00 ? 379 LEU B CD1 1 ATOM 7784 C CD2 . LEU B 1 379 ? 46.086 18.060 35.880 1.00 2.00 ? 379 LEU B CD2 1 ATOM 7785 N N . PHE B 1 380 ? 41.671 19.944 32.955 1.00 2.92 ? 380 PHE B N 1 ATOM 7786 C CA . PHE B 1 380 ? 40.369 20.629 33.031 1.00 2.00 ? 380 PHE B CA 1 ATOM 7787 C C . PHE B 1 380 ? 39.324 19.650 33.519 1.00 2.37 ? 380 PHE B C 1 ATOM 7788 O O . PHE B 1 380 ? 39.202 18.549 32.985 1.00 4.20 ? 380 PHE B O 1 ATOM 7789 C CB . PHE B 1 380 ? 39.901 21.155 31.672 1.00 2.00 ? 380 PHE B CB 1 ATOM 7790 C CG . PHE B 1 380 ? 40.903 21.997 30.974 1.00 2.00 ? 380 PHE B CG 1 ATOM 7791 C CD1 . PHE B 1 380 ? 41.587 22.988 31.655 1.00 2.00 ? 380 PHE B CD1 1 ATOM 7792 C CD2 . PHE B 1 380 ? 41.183 21.782 29.633 1.00 2.32 ? 380 PHE B CD2 1 ATOM 7793 C CE1 . PHE B 1 380 ? 42.539 23.750 31.019 1.00 2.00 ? 380 PHE B CE1 1 ATOM 7794 C CE2 . PHE B 1 380 ? 42.136 22.542 28.982 1.00 2.64 ? 380 PHE B CE2 1 ATOM 7795 C CZ . PHE B 1 380 ? 42.818 23.529 29.678 1.00 2.38 ? 380 PHE B CZ 1 ATOM 7796 N N . PHE B 1 381 ? 38.556 20.056 34.521 1.00 3.17 ? 381 PHE B N 1 ATOM 7797 C CA . PHE B 1 381 ? 37.528 19.195 35.084 1.00 2.00 ? 381 PHE B CA 1 ATOM 7798 C C . PHE B 1 381 ? 38.149 17.903 35.546 1.00 2.00 ? 381 PHE B C 1 ATOM 7799 O O . PHE B 1 381 ? 37.599 16.828 35.345 1.00 2.00 ? 381 PHE B O 1 ATOM 7800 C CB . PHE B 1 381 ? 36.459 18.918 34.044 1.00 2.00 ? 381 PHE B CB 1 ATOM 7801 C CG . PHE B 1 381 ? 35.710 20.132 33.651 1.00 2.51 ? 381 PHE B CG 1 ATOM 7802 C CD1 . PHE B 1 381 ? 34.828 20.727 34.541 1.00 3.29 ? 381 PHE B CD1 1 ATOM 7803 C CD2 . PHE B 1 381 ? 35.927 20.721 32.422 1.00 2.79 ? 381 PHE B CD2 1 ATOM 7804 C CE1 . PHE B 1 381 ? 34.174 21.895 34.214 1.00 4.18 ? 381 PHE B CE1 1 ATOM 7805 C CE2 . PHE B 1 381 ? 35.280 21.890 32.084 1.00 4.54 ? 381 PHE B CE2 1 ATOM 7806 C CZ . PHE B 1 381 ? 34.401 22.480 32.986 1.00 4.65 ? 381 PHE B CZ 1 ATOM 7807 N N . ASN B 1 382 ? 39.309 18.025 36.173 1.00 2.00 ? 382 ASN B N 1 ATOM 7808 C CA . ASN B 1 382 ? 40.028 16.873 36.674 1.00 2.00 ? 382 ASN B CA 1 ATOM 7809 C C . ASN B 1 382 ? 40.142 16.912 38.195 1.00 3.36 ? 382 ASN B C 1 ATOM 7810 O O . ASN B 1 382 ? 40.766 17.813 38.760 1.00 3.87 ? 382 ASN B O 1 ATOM 7811 C CB . ASN B 1 382 ? 41.420 16.825 36.060 1.00 2.00 ? 382 ASN B CB 1 ATOM 7812 C CG . ASN B 1 382 ? 42.143 15.560 36.400 1.00 2.00 ? 382 ASN B CG 1 ATOM 7813 O OD1 . ASN B 1 382 ? 42.310 15.227 37.569 1.00 2.35 ? 382 ASN B OD1 1 ATOM 7814 N ND2 . ASN B 1 382 ? 42.575 14.837 35.382 1.00 2.00 ? 382 ASN B ND2 1 ATOM 7815 N N . THR B 1 383 ? 39.532 15.934 38.854 1.00 2.43 ? 383 THR B N 1 ATOM 7816 C CA . THR B 1 383 ? 39.583 15.851 40.306 1.00 2.00 ? 383 THR B CA 1 ATOM 7817 C C . THR B 1 383 ? 40.274 14.570 40.750 1.00 5.15 ? 383 THR B C 1 ATOM 7818 O O . THR B 1 383 ? 40.818 14.512 41.858 1.00 5.23 ? 383 THR B O 1 ATOM 7819 C CB . THR B 1 383 ? 38.181 15.858 40.927 1.00 2.00 ? 383 THR B CB 1 ATOM 7820 O OG1 . THR B 1 383 ? 37.335 14.961 40.198 1.00 2.34 ? 383 THR B OG1 1 ATOM 7821 C CG2 . THR B 1 383 ? 37.593 17.251 40.908 1.00 2.18 ? 383 THR B CG2 1 ATOM 7822 N N . TRP B 1 384 ? 40.257 13.543 39.897 1.00 3.47 ? 384 TRP B N 1 ATOM 7823 C CA . TRP B 1 384 ? 40.880 12.284 40.271 1.00 2.00 ? 384 TRP B CA 1 ATOM 7824 C C . TRP B 1 384 ? 42.360 12.462 40.496 1.00 2.00 ? 384 TRP B C 1 ATOM 7825 O O . TRP B 1 384 ? 42.938 11.814 41.362 1.00 2.04 ? 384 TRP B O 1 ATOM 7826 C CB . TRP B 1 384 ? 40.625 11.195 39.236 1.00 2.51 ? 384 TRP B CB 1 ATOM 7827 C CG . TRP B 1 384 ? 41.443 11.241 37.992 1.00 2.79 ? 384 TRP B CG 1 ATOM 7828 C CD1 . TRP B 1 384 ? 41.076 11.779 36.792 1.00 3.96 ? 384 TRP B CD1 1 ATOM 7829 C CD2 . TRP B 1 384 ? 42.702 10.604 37.774 1.00 2.00 ? 384 TRP B CD2 1 ATOM 7830 N NE1 . TRP B 1 384 ? 42.022 11.501 35.834 1.00 2.70 ? 384 TRP B NE1 1 ATOM 7831 C CE2 . TRP B 1 384 ? 43.034 10.781 36.412 1.00 2.00 ? 384 TRP B CE2 1 ATOM 7832 C CE3 . TRP B 1 384 ? 43.582 9.896 38.593 1.00 2.00 ? 384 TRP B CE3 1 ATOM 7833 C CZ2 . TRP B 1 384 ? 44.209 10.272 35.851 1.00 2.10 ? 384 TRP B CZ2 1 ATOM 7834 C CZ3 . TRP B 1 384 ? 44.752 9.390 38.036 1.00 3.11 ? 384 TRP B CZ3 1 ATOM 7835 C CH2 . TRP B 1 384 ? 45.053 9.582 36.677 1.00 2.32 ? 384 TRP B CH2 1 ATOM 7836 N N . ARG B 1 385 ? 42.981 13.347 39.732 1.00 2.00 ? 385 ARG B N 1 ATOM 7837 C CA . ARG B 1 385 ? 44.395 13.598 39.935 1.00 2.35 ? 385 ARG B CA 1 ATOM 7838 C C . ARG B 1 385 ? 44.580 14.175 41.326 1.00 2.00 ? 385 ARG B C 1 ATOM 7839 O O . ARG B 1 385 ? 45.701 14.315 41.798 1.00 2.13 ? 385 ARG B O 1 ATOM 7840 C CB . ARG B 1 385 ? 44.936 14.571 38.894 1.00 2.81 ? 385 ARG B CB 1 ATOM 7841 C CG . ARG B 1 385 ? 45.324 13.899 37.591 1.00 4.40 ? 385 ARG B CG 1 ATOM 7842 C CD . ARG B 1 385 ? 46.486 12.943 37.796 1.00 4.96 ? 385 ARG B CD 1 ATOM 7843 N NE . ARG B 1 385 ? 46.857 12.267 36.558 1.00 5.43 ? 385 ARG B NE 1 ATOM 7844 C CZ . ARG B 1 385 ? 48.047 11.719 36.342 1.00 5.80 ? 385 ARG B CZ 1 ATOM 7845 N NH1 . ARG B 1 385 ? 48.982 11.773 37.284 1.00 6.64 ? 385 ARG B NH1 1 ATOM 7846 N NH2 . ARG B 1 385 ? 48.302 11.119 35.186 1.00 5.00 ? 385 ARG B NH2 1 ATOM 7847 N N . ILE B 1 386 ? 43.480 14.523 41.983 1.00 2.00 ? 386 ILE B N 1 ATOM 7848 C CA . ILE B 1 386 ? 43.585 15.055 43.332 1.00 3.05 ? 386 ILE B CA 1 ATOM 7849 C C . ILE B 1 386 ? 43.236 13.980 44.336 1.00 3.46 ? 386 ILE B C 1 ATOM 7850 O O . ILE B 1 386 ? 44.062 13.626 45.175 1.00 6.39 ? 386 ILE B O 1 ATOM 7851 C CB . ILE B 1 386 ? 42.632 16.223 43.614 1.00 2.18 ? 386 ILE B CB 1 ATOM 7852 C CG1 . ILE B 1 386 ? 42.996 17.448 42.785 1.00 2.00 ? 386 ILE B CG1 1 ATOM 7853 C CG2 . ILE B 1 386 ? 42.721 16.584 45.085 1.00 2.00 ? 386 ILE B CG2 1 ATOM 7854 C CD1 . ILE B 1 386 ? 42.039 18.614 42.990 1.00 2.00 ? 386 ILE B CD1 1 ATOM 7855 N N . ILE B 1 387 ? 42.007 13.475 44.256 1.00 2.00 ? 387 ILE B N 1 ATOM 7856 C CA . ILE B 1 387 ? 41.531 12.446 45.176 1.00 2.00 ? 387 ILE B CA 1 ATOM 7857 C C . ILE B 1 387 ? 42.466 11.256 45.246 1.00 2.45 ? 387 ILE B C 1 ATOM 7858 O O . ILE B 1 387 ? 42.872 10.827 46.329 1.00 2.37 ? 387 ILE B O 1 ATOM 7859 C CB . ILE B 1 387 ? 40.173 11.883 44.750 1.00 2.42 ? 387 ILE B CB 1 ATOM 7860 C CG1 . ILE B 1 387 ? 39.107 12.986 44.755 1.00 2.92 ? 387 ILE B CG1 1 ATOM 7861 C CG2 . ILE B 1 387 ? 39.820 10.690 45.640 1.00 2.00 ? 387 ILE B CG2 1 ATOM 7862 C CD1 . ILE B 1 387 ? 38.780 13.574 46.116 1.00 2.00 ? 387 ILE B CD1 1 ATOM 7863 N N . LYS B 1 388 ? 42.789 10.737 44.062 1.00 3.86 ? 388 LYS B N 1 ATOM 7864 C CA . LYS B 1 388 ? 43.637 9.562 43.891 1.00 2.45 ? 388 LYS B CA 1 ATOM 7865 C C . LYS B 1 388 ? 45.103 9.802 43.525 1.00 2.00 ? 388 LYS B C 1 ATOM 7866 O O . LYS B 1 388 ? 45.713 8.969 42.854 1.00 2.09 ? 388 LYS B O 1 ATOM 7867 C CB . LYS B 1 388 ? 43.023 8.666 42.819 1.00 2.00 ? 388 LYS B CB 1 ATOM 7868 C CG . LYS B 1 388 ? 41.600 8.262 43.080 1.00 2.00 ? 388 LYS B CG 1 ATOM 7869 C CD . LYS B 1 388 ? 41.221 7.136 42.147 1.00 4.47 ? 388 LYS B CD 1 ATOM 7870 C CE . LYS B 1 388 ? 39.868 6.561 42.507 1.00 6.72 ? 388 LYS B CE 1 ATOM 7871 N NZ . LYS B 1 388 ? 39.801 6.167 43.948 1.00 9.46 ? 388 LYS B NZ 1 ATOM 7872 N N . ASP B 1 389 ? 45.687 10.912 43.953 1.00 2.05 ? 389 ASP B N 1 ATOM 7873 C CA . ASP B 1 389 ? 47.076 11.153 43.599 1.00 2.95 ? 389 ASP B CA 1 ATOM 7874 C C . ASP B 1 389 ? 47.771 12.182 44.480 1.00 3.31 ? 389 ASP B C 1 ATOM 7875 O O . ASP B 1 389 ? 48.062 13.293 44.040 1.00 4.45 ? 389 ASP B O 1 ATOM 7876 C CB . ASP B 1 389 ? 47.161 11.573 42.123 1.00 4.34 ? 389 ASP B CB 1 ATOM 7877 C CG . ASP B 1 389 ? 48.314 10.898 41.380 1.00 5.08 ? 389 ASP B CG 1 ATOM 7878 O OD1 . ASP B 1 389 ? 48.494 9.674 41.570 1.00 6.20 ? 389 ASP B OD1 1 ATOM 7879 O OD2 . ASP B 1 389 ? 49.027 11.580 40.600 1.00 5.16 ? 389 ASP B OD2 1 ATOM 7880 N N . GLY B 1 390 ? 48.018 11.812 45.733 1.00 3.53 ? 390 GLY B N 1 ATOM 7881 C CA . GLY B 1 390 ? 48.724 12.694 46.648 1.00 4.09 ? 390 GLY B CA 1 ATOM 7882 C C . GLY B 1 390 ? 48.007 13.848 47.321 1.00 3.52 ? 390 GLY B C 1 ATOM 7883 O O . GLY B 1 390 ? 48.627 14.585 48.085 1.00 4.13 ? 390 GLY B O 1 ATOM 7884 N N . GLY B 1 391 ? 46.717 14.023 47.062 1.00 3.87 ? 391 GLY B N 1 ATOM 7885 C CA . GLY B 1 391 ? 46.012 15.122 47.702 1.00 4.31 ? 391 GLY B CA 1 ATOM 7886 C C . GLY B 1 391 ? 46.345 16.435 47.026 1.00 4.61 ? 391 GLY B C 1 ATOM 7887 O O . GLY B 1 391 ? 46.797 16.436 45.880 1.00 6.00 ? 391 GLY B O 1 ATOM 7888 N N . ILE B 1 392 ? 46.148 17.555 47.713 1.00 2.80 ? 392 ILE B N 1 ATOM 7889 C CA . ILE B 1 392 ? 46.433 18.836 47.082 1.00 3.47 ? 392 ILE B CA 1 ATOM 7890 C C . ILE B 1 392 ? 47.676 19.525 47.635 1.00 2.44 ? 392 ILE B C 1 ATOM 7891 O O . ILE B 1 392 ? 48.055 20.620 47.204 1.00 2.00 ? 392 ILE B O 1 ATOM 7892 C CB . ILE B 1 392 ? 45.182 19.772 47.151 1.00 4.34 ? 392 ILE B CB 1 ATOM 7893 C CG1 . ILE B 1 392 ? 45.281 20.795 48.304 1.00 4.98 ? 392 ILE B CG1 1 ATOM 7894 C CG2 . ILE B 1 392 ? 43.934 18.911 47.242 1.00 3.44 ? 392 ILE B CG2 1 ATOM 7895 C CD1 . ILE B 1 392 ? 45.323 20.225 49.708 1.00 5.79 ? 392 ILE B CD1 1 ATOM 7896 N N . ASP B 1 393 ? 48.322 18.862 48.581 1.00 2.47 ? 393 ASP B N 1 ATOM 7897 C CA . ASP B 1 393 ? 49.531 19.393 49.177 1.00 3.07 ? 393 ASP B CA 1 ATOM 7898 C C . ASP B 1 393 ? 50.614 19.557 48.136 1.00 4.57 ? 393 ASP B C 1 ATOM 7899 O O . ASP B 1 393 ? 51.284 20.586 48.095 1.00 7.57 ? 393 ASP B O 1 ATOM 7900 C CB . ASP B 1 393 ? 50.013 18.472 50.277 1.00 4.59 ? 393 ASP B CB 1 ATOM 7901 C CG . ASP B 1 393 ? 49.612 18.959 51.629 1.00 5.67 ? 393 ASP B CG 1 ATOM 7902 O OD1 . ASP B 1 393 ? 48.567 19.644 51.727 1.00 5.21 ? 393 ASP B OD1 1 ATOM 7903 O OD2 . ASP B 1 393 ? 50.343 18.653 52.590 1.00 7.91 ? 393 ASP B OD2 1 ATOM 7904 N N . PRO B 1 394 ? 50.825 18.534 47.290 1.00 5.40 ? 394 PRO B N 1 ATOM 7905 C CA . PRO B 1 394 ? 51.858 18.644 46.254 1.00 3.86 ? 394 PRO B CA 1 ATOM 7906 C C . PRO B 1 394 ? 51.499 19.658 45.160 1.00 3.53 ? 394 PRO B C 1 ATOM 7907 O O . PRO B 1 394 ? 52.374 20.104 44.417 1.00 3.50 ? 394 PRO B O 1 ATOM 7908 C CB . PRO B 1 394 ? 51.969 17.214 45.718 1.00 3.32 ? 394 PRO B CB 1 ATOM 7909 C CG . PRO B 1 394 ? 50.601 16.642 45.965 1.00 3.34 ? 394 PRO B CG 1 ATOM 7910 C CD . PRO B 1 394 ? 50.297 17.159 47.352 1.00 4.87 ? 394 PRO B CD 1 ATOM 7911 N N . LEU B 1 395 ? 50.217 20.013 45.060 1.00 2.93 ? 395 LEU B N 1 ATOM 7912 C CA . LEU B 1 395 ? 49.777 20.987 44.065 1.00 2.94 ? 395 LEU B CA 1 ATOM 7913 C C . LEU B 1 395 ? 49.994 22.405 44.626 1.00 3.33 ? 395 LEU B C 1 ATOM 7914 O O . LEU B 1 395 ? 50.440 23.307 43.907 1.00 4.12 ? 395 LEU B O 1 ATOM 7915 C CB . LEU B 1 395 ? 48.299 20.764 43.695 1.00 2.00 ? 395 LEU B CB 1 ATOM 7916 C CG . LEU B 1 395 ? 47.863 19.542 42.872 1.00 2.00 ? 395 LEU B CG 1 ATOM 7917 C CD1 . LEU B 1 395 ? 46.365 19.568 42.703 1.00 2.00 ? 395 LEU B CD1 1 ATOM 7918 C CD2 . LEU B 1 395 ? 48.509 19.549 41.516 1.00 2.00 ? 395 LEU B CD2 1 ATOM 7919 N N . VAL B 1 396 ? 49.686 22.595 45.908 1.00 2.00 ? 396 VAL B N 1 ATOM 7920 C CA . VAL B 1 396 ? 49.882 23.889 46.553 1.00 2.00 ? 396 VAL B CA 1 ATOM 7921 C C . VAL B 1 396 ? 51.360 24.275 46.511 1.00 2.80 ? 396 VAL B C 1 ATOM 7922 O O . VAL B 1 396 ? 51.704 25.455 46.432 1.00 3.48 ? 396 VAL B O 1 ATOM 7923 C CB . VAL B 1 396 ? 49.404 23.854 48.017 1.00 2.00 ? 396 VAL B CB 1 ATOM 7924 C CG1 . VAL B 1 396 ? 50.073 24.946 48.828 1.00 2.00 ? 396 VAL B CG1 1 ATOM 7925 C CG2 . VAL B 1 396 ? 47.909 24.027 48.053 1.00 2.65 ? 396 VAL B CG2 1 ATOM 7926 N N . ARG B 1 397 ? 52.239 23.283 46.568 1.00 2.76 ? 397 ARG B N 1 ATOM 7927 C CA . ARG B 1 397 ? 53.656 23.582 46.522 1.00 3.28 ? 397 ARG B CA 1 ATOM 7928 C C . ARG B 1 397 ? 53.973 24.084 45.133 1.00 2.24 ? 397 ARG B C 1 ATOM 7929 O O . ARG B 1 397 ? 54.700 25.057 44.967 1.00 2.89 ? 397 ARG B O 1 ATOM 7930 C CB . ARG B 1 397 ? 54.488 22.342 46.825 1.00 5.80 ? 397 ARG B CB 1 ATOM 7931 C CG . ARG B 1 397 ? 54.444 21.898 48.274 1.00 8.41 ? 397 ARG B CG 1 ATOM 7932 C CD . ARG B 1 397 ? 55.805 21.378 48.715 1.00 9.39 ? 397 ARG B CD 1 ATOM 7933 N NE . ARG B 1 397 ? 55.693 20.488 49.862 1.00 10.93 ? 397 ARG B NE 1 ATOM 7934 C CZ . ARG B 1 397 ? 55.042 19.330 49.833 1.00 12.18 ? 397 ARG B CZ 1 ATOM 7935 N NH1 . ARG B 1 397 ? 54.447 18.927 48.717 1.00 12.80 ? 397 ARG B NH1 1 ATOM 7936 N NH2 . ARG B 1 397 ? 54.988 18.570 50.918 1.00 14.01 ? 397 ARG B NH2 1 ATOM 7937 N N . GLY B 1 398 ? 53.422 23.412 44.133 1.00 2.00 ? 398 GLY B N 1 ATOM 7938 C CA . GLY B 1 398 ? 53.651 23.834 42.768 1.00 2.19 ? 398 GLY B CA 1 ATOM 7939 C C . GLY B 1 398 ? 53.382 25.319 42.655 1.00 2.72 ? 398 GLY B C 1 ATOM 7940 O O . GLY B 1 398 ? 54.241 26.084 42.214 1.00 3.66 ? 398 GLY B O 1 ATOM 7941 N N . LEU B 1 399 ? 52.189 25.728 43.077 1.00 3.39 ? 399 LEU B N 1 ATOM 7942 C CA . LEU B 1 399 ? 51.782 27.133 43.034 1.00 3.67 ? 399 LEU B CA 1 ATOM 7943 C C . LEU B 1 399 ? 52.758 28.080 43.739 1.00 3.59 ? 399 LEU B C 1 ATOM 7944 O O . LEU B 1 399 ? 52.954 29.221 43.317 1.00 4.72 ? 399 LEU B O 1 ATOM 7945 C CB . LEU B 1 399 ? 50.387 27.292 43.647 1.00 2.49 ? 399 LEU B CB 1 ATOM 7946 C CG . LEU B 1 399 ? 49.198 27.010 42.732 1.00 2.00 ? 399 LEU B CG 1 ATOM 7947 C CD1 . LEU B 1 399 ? 47.998 26.643 43.577 1.00 2.00 ? 399 LEU B CD1 1 ATOM 7948 C CD2 . LEU B 1 399 ? 48.921 28.224 41.862 1.00 2.00 ? 399 LEU B CD2 1 ATOM 7949 N N . LEU B 1 400 ? 53.374 27.620 44.815 1.00 3.25 ? 400 LEU B N 1 ATOM 7950 C CA . LEU B 1 400 ? 54.296 28.482 45.518 1.00 2.00 ? 400 LEU B CA 1 ATOM 7951 C C . LEU B 1 400 ? 55.664 28.568 44.850 1.00 2.04 ? 400 LEU B C 1 ATOM 7952 O O . LEU B 1 400 ? 56.221 29.658 44.746 1.00 3.11 ? 400 LEU B O 1 ATOM 7953 C CB . LEU B 1 400 ? 54.438 28.024 46.971 1.00 2.00 ? 400 LEU B CB 1 ATOM 7954 C CG . LEU B 1 400 ? 53.220 28.281 47.857 1.00 2.00 ? 400 LEU B CG 1 ATOM 7955 C CD1 . LEU B 1 400 ? 53.514 27.834 49.271 1.00 2.00 ? 400 LEU B CD1 1 ATOM 7956 C CD2 . LEU B 1 400 ? 52.884 29.766 47.837 1.00 2.16 ? 400 LEU B CD2 1 ATOM 7957 N N . ALA B 1 401 ? 56.182 27.437 44.364 1.00 2.00 ? 401 ALA B N 1 ATOM 7958 C CA . ALA B 1 401 ? 57.515 27.388 43.757 1.00 2.00 ? 401 ALA B CA 1 ATOM 7959 C C . ALA B 1 401 ? 57.640 27.661 42.261 1.00 3.69 ? 401 ALA B C 1 ATOM 7960 O O . ALA B 1 401 ? 58.605 28.296 41.835 1.00 4.97 ? 401 ALA B O 1 ATOM 7961 C CB . ALA B 1 401 ? 58.171 26.058 44.082 1.00 2.00 ? 401 ALA B CB 1 ATOM 7962 N N . LYS B 1 402 ? 56.696 27.176 41.460 1.00 2.02 ? 402 LYS B N 1 ATOM 7963 C CA . LYS B 1 402 ? 56.749 27.405 40.016 1.00 2.70 ? 402 LYS B CA 1 ATOM 7964 C C . LYS B 1 402 ? 56.138 28.754 39.643 1.00 2.00 ? 402 LYS B C 1 ATOM 7965 O O . LYS B 1 402 ? 55.289 29.255 40.363 1.00 2.05 ? 402 LYS B O 1 ATOM 7966 C CB . LYS B 1 402 ? 56.009 26.291 39.285 1.00 4.62 ? 402 LYS B CB 1 ATOM 7967 C CG . LYS B 1 402 ? 56.703 24.951 39.342 1.00 7.20 ? 402 LYS B CG 1 ATOM 7968 C CD . LYS B 1 402 ? 57.951 24.937 38.480 1.00 10.49 ? 402 LYS B CD 1 ATOM 7969 C CE . LYS B 1 402 ? 58.575 23.548 38.486 1.00 12.71 ? 402 LYS B CE 1 ATOM 7970 N NZ . LYS B 1 402 ? 59.854 23.479 37.721 1.00 14.66 ? 402 LYS B NZ 1 ATOM 7971 N N . LYS B 1 403 ? 56.564 29.326 38.514 1.00 2.34 ? 403 LYS B N 1 ATOM 7972 C CA . LYS B 1 403 ? 56.071 30.631 38.033 1.00 3.10 ? 403 LYS B CA 1 ATOM 7973 C C . LYS B 1 403 ? 54.998 30.544 36.931 1.00 4.48 ? 403 LYS B C 1 ATOM 7974 O O . LYS B 1 403 ? 54.839 29.512 36.260 1.00 4.75 ? 403 LYS B O 1 ATOM 7975 C CB . LYS B 1 403 ? 57.216 31.475 37.457 1.00 2.43 ? 403 LYS B CB 1 ATOM 7976 C CG . LYS B 1 403 ? 58.581 31.283 38.080 1.00 5.97 ? 403 LYS B CG 1 ATOM 7977 C CD . LYS B 1 403 ? 59.681 31.815 37.147 1.00 7.87 ? 403 LYS B CD 1 ATOM 7978 C CE . LYS B 1 403 ? 61.089 31.551 37.697 1.00 10.61 ? 403 LYS B CE 1 ATOM 7979 N NZ . LYS B 1 403 ? 61.356 30.097 37.958 1.00 13.09 ? 403 LYS B NZ 1 ATOM 7980 N N . SER B 1 404 ? 54.304 31.664 36.725 1.00 3.76 ? 404 SER B N 1 ATOM 7981 C CA . SER B 1 404 ? 53.256 31.780 35.708 1.00 3.66 ? 404 SER B CA 1 ATOM 7982 C C . SER B 1 404 ? 53.843 32.231 34.372 1.00 4.04 ? 404 SER B C 1 ATOM 7983 O O . SER B 1 404 ? 55.024 32.562 34.272 1.00 4.80 ? 404 SER B O 1 ATOM 7984 C CB . SER B 1 404 ? 52.219 32.824 36.125 1.00 4.58 ? 404 SER B CB 1 ATOM 7985 O OG . SER B 1 404 ? 52.216 33.035 37.525 1.00 9.50 ? 404 SER B OG 1 ATOM 7986 N N . LYS B 1 405 ? 53.003 32.258 33.346 1.00 3.47 ? 405 LYS B N 1 ATOM 7987 C CA . LYS B 1 405 ? 53.430 32.705 32.030 1.00 2.05 ? 405 LYS B CA 1 ATOM 7988 C C . LYS B 1 405 ? 53.367 34.219 31.988 1.00 2.00 ? 405 LYS B C 1 ATOM 7989 O O . LYS B 1 405 ? 52.548 34.819 32.671 1.00 2.03 ? 405 LYS B O 1 ATOM 7990 C CB . LYS B 1 405 ? 52.510 32.161 30.948 1.00 2.00 ? 405 LYS B CB 1 ATOM 7991 C CG . LYS B 1 405 ? 52.686 32.868 29.622 1.00 2.00 ? 405 LYS B CG 1 ATOM 7992 C CD . LYS B 1 405 ? 51.808 32.259 28.573 1.00 2.00 ? 405 LYS B CD 1 ATOM 7993 C CE . LYS B 1 405 ? 52.085 32.891 27.242 1.00 2.00 ? 405 LYS B CE 1 ATOM 7994 N NZ . LYS B 1 405 ? 51.723 34.313 27.299 1.00 2.00 ? 405 LYS B NZ 1 ATOM 7995 N N . LEU B 1 406 ? 54.223 34.832 31.179 1.00 2.00 ? 406 LEU B N 1 ATOM 7996 C CA . LEU B 1 406 ? 54.245 36.284 31.042 1.00 2.18 ? 406 LEU B CA 1 ATOM 7997 C C . LEU B 1 406 ? 53.569 36.653 29.717 1.00 2.78 ? 406 LEU B C 1 ATOM 7998 O O . LEU B 1 406 ? 53.751 35.952 28.729 1.00 3.20 ? 406 LEU B O 1 ATOM 7999 C CB . LEU B 1 406 ? 55.690 36.783 31.041 1.00 2.00 ? 406 LEU B CB 1 ATOM 8000 C CG . LEU B 1 406 ? 55.842 38.300 30.979 1.00 2.00 ? 406 LEU B CG 1 ATOM 8001 C CD1 . LEU B 1 406 ? 55.459 38.893 32.316 1.00 3.24 ? 406 LEU B CD1 1 ATOM 8002 C CD2 . LEU B 1 406 ? 57.261 38.669 30.629 1.00 2.00 ? 406 LEU B CD2 1 ATOM 8003 N N . MET B 1 407 ? 52.789 37.734 29.681 1.00 2.00 ? 407 MET B N 1 ATOM 8004 C CA . MET B 1 407 ? 52.131 38.115 28.431 1.00 2.29 ? 407 MET B CA 1 ATOM 8005 C C . MET B 1 407 ? 53.168 38.687 27.475 1.00 3.36 ? 407 MET B C 1 ATOM 8006 O O . MET B 1 407 ? 53.796 39.707 27.758 1.00 4.70 ? 407 MET B O 1 ATOM 8007 C CB . MET B 1 407 ? 51.032 39.154 28.684 1.00 3.71 ? 407 MET B CB 1 ATOM 8008 C CG . MET B 1 407 ? 50.148 39.504 27.474 1.00 2.32 ? 407 MET B CG 1 ATOM 8009 S SD . MET B 1 407 ? 50.978 40.383 26.121 1.00 6.00 ? 407 MET B SD 1 ATOM 8010 C CE . MET B 1 407 ? 51.272 42.026 26.851 1.00 2.00 ? 407 MET B CE 1 ATOM 8011 N N . ASN B 1 408 ? 53.338 38.024 26.340 1.00 3.95 ? 408 ASN B N 1 ATOM 8012 C CA . ASN B 1 408 ? 54.301 38.444 25.334 1.00 4.90 ? 408 ASN B CA 1 ATOM 8013 C C . ASN B 1 408 ? 53.521 38.796 24.079 1.00 3.20 ? 408 ASN B C 1 ATOM 8014 O O . ASN B 1 408 ? 52.699 38.004 23.625 1.00 3.16 ? 408 ASN B O 1 ATOM 8015 C CB . ASN B 1 408 ? 55.275 37.293 25.063 1.00 8.41 ? 408 ASN B CB 1 ATOM 8016 C CG . ASN B 1 408 ? 56.555 37.749 24.387 1.00 11.83 ? 408 ASN B CG 1 ATOM 8017 O OD1 . ASN B 1 408 ? 56.626 37.839 23.157 1.00 13.08 ? 408 ASN B OD1 1 ATOM 8018 N ND2 . ASN B 1 408 ? 57.577 38.049 25.193 1.00 12.78 ? 408 ASN B ND2 1 ATOM 8019 N N . GLN B 1 409 ? 53.767 39.972 23.513 1.00 2.90 ? 409 GLN B N 1 ATOM 8020 C CA . GLN B 1 409 ? 53.033 40.376 22.320 1.00 4.10 ? 409 GLN B CA 1 ATOM 8021 C C . GLN B 1 409 ? 52.995 39.323 21.232 1.00 5.16 ? 409 GLN B C 1 ATOM 8022 O O . GLN B 1 409 ? 52.062 39.299 20.419 1.00 4.50 ? 409 GLN B O 1 ATOM 8023 C CB . GLN B 1 409 ? 53.588 41.671 21.748 1.00 3.14 ? 409 GLN B CB 1 ATOM 8024 C CG . GLN B 1 409 ? 52.815 42.851 22.204 1.00 4.36 ? 409 GLN B CG 1 ATOM 8025 C CD . GLN B 1 409 ? 53.594 44.119 22.075 1.00 6.53 ? 409 GLN B CD 1 ATOM 8026 O OE1 . GLN B 1 409 ? 54.743 44.212 22.502 1.00 8.01 ? 409 GLN B OE1 1 ATOM 8027 N NE2 . GLN B 1 409 ? 52.976 45.132 21.487 1.00 9.51 ? 409 GLN B NE2 1 ATOM 8028 N N . ASN B 1 410 ? 54.006 38.452 21.213 1.00 5.39 ? 410 ASN B N 1 ATOM 8029 C CA . ASN B 1 410 ? 54.059 37.390 20.218 1.00 6.32 ? 410 ASN B CA 1 ATOM 8030 C C . ASN B 1 410 ? 54.131 35.977 20.842 1.00 3.94 ? 410 ASN B C 1 ATOM 8031 O O . ASN B 1 410 ? 54.850 35.088 20.393 1.00 2.88 ? 410 ASN B O 1 ATOM 8032 C CB . ASN B 1 410 ? 55.173 37.701 19.176 1.00 8.87 ? 410 ASN B CB 1 ATOM 8033 C CG . ASN B 1 410 ? 56.449 36.916 19.376 1.00 11.67 ? 410 ASN B CG 1 ATOM 8034 O OD1 . ASN B 1 410 ? 57.414 37.416 19.955 1.00 14.04 ? 410 ASN B OD1 1 ATOM 8035 N ND2 . ASN B 1 410 ? 56.476 35.682 18.867 1.00 14.40 ? 410 ASN B ND2 1 ATOM 8036 N N . LYS B 1 411 ? 53.322 35.818 21.886 1.00 5.33 ? 411 LYS B N 1 ATOM 8037 C CA . LYS B 1 411 ? 53.114 34.585 22.661 1.00 4.12 ? 411 LYS B CA 1 ATOM 8038 C C . LYS B 1 411 ? 51.999 34.926 23.646 1.00 2.30 ? 411 LYS B C 1 ATOM 8039 O O . LYS B 1 411 ? 52.224 35.068 24.841 1.00 2.00 ? 411 LYS B O 1 ATOM 8040 C CB . LYS B 1 411 ? 54.363 34.132 23.435 1.00 3.92 ? 411 LYS B CB 1 ATOM 8041 C CG . LYS B 1 411 ? 55.406 33.387 22.594 1.00 4.49 ? 411 LYS B CG 1 ATOM 8042 C CD . LYS B 1 411 ? 56.554 32.805 23.436 1.00 4.20 ? 411 LYS B CD 1 ATOM 8043 C CE . LYS B 1 411 ? 57.738 32.436 22.537 1.00 5.17 ? 411 LYS B CE 1 ATOM 8044 N NZ . LYS B 1 411 ? 58.821 31.635 23.187 1.00 4.02 ? 411 LYS B NZ 1 ATOM 8045 N N . MET B 1 412 ? 50.790 35.065 23.116 1.00 2.00 ? 412 MET B N 1 ATOM 8046 C CA . MET B 1 412 ? 49.641 35.434 23.914 1.00 2.00 ? 412 MET B CA 1 ATOM 8047 C C . MET B 1 412 ? 48.978 34.351 24.752 1.00 2.93 ? 412 MET B C 1 ATOM 8048 O O . MET B 1 412 ? 48.932 34.436 25.979 1.00 3.12 ? 412 MET B O 1 ATOM 8049 C CB . MET B 1 412 ? 48.608 36.100 23.005 1.00 2.00 ? 412 MET B CB 1 ATOM 8050 C CG . MET B 1 412 ? 49.039 37.489 22.567 1.00 2.44 ? 412 MET B CG 1 ATOM 8051 S SD . MET B 1 412 ? 47.725 38.484 21.846 1.00 2.00 ? 412 MET B SD 1 ATOM 8052 C CE . MET B 1 412 ? 48.551 39.180 20.433 1.00 2.00 ? 412 MET B CE 1 ATOM 8053 N N . VAL B 1 413 ? 48.470 33.324 24.089 1.00 3.78 ? 413 VAL B N 1 ATOM 8054 C CA . VAL B 1 413 ? 47.771 32.255 24.780 1.00 2.87 ? 413 VAL B CA 1 ATOM 8055 C C . VAL B 1 413 ? 48.339 30.885 24.444 1.00 4.31 ? 413 VAL B C 1 ATOM 8056 O O . VAL B 1 413 ? 48.386 30.506 23.283 1.00 7.46 ? 413 VAL B O 1 ATOM 8057 C CB . VAL B 1 413 ? 46.282 32.297 24.395 1.00 2.00 ? 413 VAL B CB 1 ATOM 8058 C CG1 . VAL B 1 413 ? 45.574 31.028 24.840 1.00 2.00 ? 413 VAL B CG1 1 ATOM 8059 C CG2 . VAL B 1 413 ? 45.592 33.508 25.005 1.00 2.00 ? 413 VAL B CG2 1 ATOM 8060 N N . THR B 1 414 ? 48.755 30.138 25.453 1.00 2.35 ? 414 THR B N 1 ATOM 8061 C CA . THR B 1 414 ? 49.280 28.811 25.194 1.00 2.00 ? 414 THR B CA 1 ATOM 8062 C C . THR B 1 414 ? 48.265 27.931 24.455 1.00 2.00 ? 414 THR B C 1 ATOM 8063 O O . THR B 1 414 ? 47.063 28.038 24.669 1.00 2.15 ? 414 THR B O 1 ATOM 8064 C CB . THR B 1 414 ? 49.540 28.082 26.488 1.00 2.00 ? 414 THR B CB 1 ATOM 8065 O OG1 . THR B 1 414 ? 50.021 26.757 26.199 1.00 2.00 ? 414 THR B OG1 1 ATOM 8066 C CG2 . THR B 1 414 ? 48.266 28.004 27.308 1.00 2.70 ? 414 THR B CG2 1 ATOM 8067 N N . SER B 1 415 ? 48.763 27.036 23.608 1.00 3.16 ? 415 SER B N 1 ATOM 8068 C CA . SER B 1 415 ? 47.906 26.104 22.827 1.00 2.00 ? 415 SER B CA 1 ATOM 8069 C C . SER B 1 415 ? 47.069 25.193 23.722 1.00 2.00 ? 415 SER B C 1 ATOM 8070 O O . SER B 1 415 ? 46.001 24.720 23.331 1.00 2.00 ? 415 SER B O 1 ATOM 8071 C CB . SER B 1 415 ? 48.760 25.233 21.907 1.00 2.00 ? 415 SER B CB 1 ATOM 8072 O OG . SER B 1 415 ? 49.499 26.015 20.986 1.00 4.32 ? 415 SER B OG 1 ATOM 8073 N N . GLU B 1 416 ? 47.547 24.974 24.936 1.00 2.00 ? 416 GLU B N 1 ATOM 8074 C CA . GLU B 1 416 ? 46.851 24.114 25.862 1.00 3.39 ? 416 GLU B CA 1 ATOM 8075 C C . GLU B 1 416 ? 45.511 24.758 26.166 1.00 2.06 ? 416 GLU B C 1 ATOM 8076 O O . GLU B 1 416 ? 44.567 24.088 26.585 1.00 2.00 ? 416 GLU B O 1 ATOM 8077 C CB . GLU B 1 416 ? 47.695 23.917 27.128 1.00 3.30 ? 416 GLU B CB 1 ATOM 8078 C CG . GLU B 1 416 ? 48.984 23.096 26.899 1.00 2.94 ? 416 GLU B CG 1 ATOM 8079 C CD . GLU B 1 416 ? 48.730 21.596 26.754 1.00 2.32 ? 416 GLU B CD 1 ATOM 8080 O OE1 . GLU B 1 416 ? 49.123 20.996 25.723 1.00 2.00 ? 416 GLU B OE1 1 ATOM 8081 O OE2 . GLU B 1 416 ? 48.141 21.020 27.689 1.00 2.00 ? 416 GLU B OE2 1 ATOM 8082 N N . LEU B 1 417 ? 45.431 26.063 25.934 1.00 2.00 ? 417 LEU B N 1 ATOM 8083 C CA . LEU B 1 417 ? 44.190 26.791 26.153 1.00 2.00 ? 417 LEU B CA 1 ATOM 8084 C C . LEU B 1 417 ? 43.565 27.267 24.842 1.00 3.43 ? 417 LEU B C 1 ATOM 8085 O O . LEU B 1 417 ? 42.358 27.512 24.777 1.00 4.05 ? 417 LEU B O 1 ATOM 8086 C CB . LEU B 1 417 ? 44.418 27.998 27.063 1.00 2.00 ? 417 LEU B CB 1 ATOM 8087 C CG . LEU B 1 417 ? 43.950 27.818 28.503 1.00 2.00 ? 417 LEU B CG 1 ATOM 8088 C CD1 . LEU B 1 417 ? 43.988 29.154 29.213 1.00 2.00 ? 417 LEU B CD1 1 ATOM 8089 C CD2 . LEU B 1 417 ? 42.542 27.246 28.517 1.00 2.00 ? 417 LEU B CD2 1 ATOM 8090 N N . ARG B 1 418 ? 44.378 27.386 23.797 1.00 3.06 ? 418 ARG B N 1 ATOM 8091 C CA . ARG B 1 418 ? 43.882 27.864 22.509 1.00 2.00 ? 418 ARG B CA 1 ATOM 8092 C C . ARG B 1 418 ? 43.631 26.764 21.484 1.00 2.08 ? 418 ARG B C 1 ATOM 8093 O O . ARG B 1 418 ? 43.293 27.055 20.337 1.00 2.00 ? 418 ARG B O 1 ATOM 8094 C CB . ARG B 1 418 ? 44.867 28.878 21.919 1.00 2.04 ? 418 ARG B CB 1 ATOM 8095 C CG . ARG B 1 418 ? 44.331 29.705 20.753 1.00 2.00 ? 418 ARG B CG 1 ATOM 8096 C CD . ARG B 1 418 ? 45.463 30.459 20.076 1.00 2.00 ? 418 ARG B CD 1 ATOM 8097 N NE . ARG B 1 418 ? 46.207 29.568 19.201 1.00 2.07 ? 418 ARG B NE 1 ATOM 8098 C CZ . ARG B 1 418 ? 45.811 29.241 17.976 1.00 2.90 ? 418 ARG B CZ 1 ATOM 8099 N NH1 . ARG B 1 418 ? 44.688 29.751 17.493 1.00 3.36 ? 418 ARG B NH1 1 ATOM 8100 N NH2 . ARG B 1 418 ? 46.514 28.382 17.247 1.00 2.46 ? 418 ARG B NH2 1 ATOM 8101 N N . ASN B 1 419 ? 43.791 25.505 21.883 1.00 2.97 ? 419 ASN B N 1 ATOM 8102 C CA . ASN B 1 419 ? 43.576 24.408 20.946 1.00 2.00 ? 419 ASN B CA 1 ATOM 8103 C C . ASN B 1 419 ? 42.995 23.147 21.548 1.00 2.00 ? 419 ASN B C 1 ATOM 8104 O O . ASN B 1 419 ? 42.315 22.388 20.863 1.00 2.00 ? 419 ASN B O 1 ATOM 8105 C CB . ASN B 1 419 ? 44.881 24.059 20.240 1.00 2.00 ? 419 ASN B CB 1 ATOM 8106 C CG . ASN B 1 419 ? 44.910 24.546 18.815 1.00 2.00 ? 419 ASN B CG 1 ATOM 8107 O OD1 . ASN B 1 419 ? 43.974 24.309 18.052 1.00 2.30 ? 419 ASN B OD1 1 ATOM 8108 N ND2 . ASN B 1 419 ? 45.987 25.225 18.441 1.00 2.00 ? 419 ASN B ND2 1 ATOM 8109 N N . LYS B 1 420 ? 43.259 22.929 22.831 1.00 2.10 ? 420 LYS B N 1 ATOM 8110 C CA . LYS B 1 420 ? 42.777 21.740 23.513 1.00 2.00 ? 420 LYS B CA 1 ATOM 8111 C C . LYS B 1 420 ? 41.932 22.053 24.750 1.00 2.22 ? 420 LYS B C 1 ATOM 8112 O O . LYS B 1 420 ? 42.210 21.543 25.829 1.00 3.53 ? 420 LYS B O 1 ATOM 8113 C CB . LYS B 1 420 ? 43.979 20.877 23.916 1.00 2.00 ? 420 LYS B CB 1 ATOM 8114 C CG . LYS B 1 420 ? 44.909 20.502 22.759 1.00 2.11 ? 420 LYS B CG 1 ATOM 8115 C CD . LYS B 1 420 ? 45.990 19.491 23.168 1.00 2.00 ? 420 LYS B CD 1 ATOM 8116 C CE . LYS B 1 420 ? 47.380 20.121 23.168 1.00 2.00 ? 420 LYS B CE 1 ATOM 8117 N NZ . LYS B 1 420 ? 48.333 19.382 22.297 1.00 2.18 ? 420 LYS B NZ 1 ATOM 8118 N N . LEU B 1 421 ? 40.896 22.874 24.609 1.00 2.07 ? 421 LEU B N 1 ATOM 8119 C CA . LEU B 1 421 ? 40.069 23.222 25.766 1.00 2.00 ? 421 LEU B CA 1 ATOM 8120 C C . LEU B 1 421 ? 38.889 22.290 25.925 1.00 2.00 ? 421 LEU B C 1 ATOM 8121 O O . LEU B 1 421 ? 38.252 21.917 24.944 1.00 2.00 ? 421 LEU B O 1 ATOM 8122 C CB . LEU B 1 421 ? 39.558 24.665 25.655 1.00 2.56 ? 421 LEU B CB 1 ATOM 8123 C CG . LEU B 1 421 ? 38.718 25.255 26.799 1.00 2.00 ? 421 LEU B CG 1 ATOM 8124 C CD1 . LEU B 1 421 ? 39.435 25.079 28.121 1.00 2.00 ? 421 LEU B CD1 1 ATOM 8125 C CD2 . LEU B 1 421 ? 38.459 26.728 26.531 1.00 2.00 ? 421 LEU B CD2 1 ATOM 8126 N N . PHE B 1 422 ? 38.597 21.918 27.167 1.00 2.00 ? 422 PHE B N 1 ATOM 8127 C CA . PHE B 1 422 ? 37.471 21.035 27.443 1.00 2.08 ? 422 PHE B CA 1 ATOM 8128 C C . PHE B 1 422 ? 36.250 21.832 27.893 1.00 2.63 ? 422 PHE B C 1 ATOM 8129 O O . PHE B 1 422 ? 36.324 22.613 28.842 1.00 2.24 ? 422 PHE B O 1 ATOM 8130 C CB . PHE B 1 422 ? 37.825 20.032 28.543 1.00 2.03 ? 422 PHE B CB 1 ATOM 8131 C CG . PHE B 1 422 ? 36.876 18.858 28.628 1.00 2.17 ? 422 PHE B CG 1 ATOM 8132 C CD1 . PHE B 1 422 ? 36.855 17.892 27.627 1.00 2.11 ? 422 PHE B CD1 1 ATOM 8133 C CD2 . PHE B 1 422 ? 36.017 18.709 29.710 1.00 2.00 ? 422 PHE B CD2 1 ATOM 8134 C CE1 . PHE B 1 422 ? 36.000 16.799 27.706 1.00 2.00 ? 422 PHE B CE1 1 ATOM 8135 C CE2 . PHE B 1 422 ? 35.156 17.614 29.793 1.00 2.00 ? 422 PHE B CE2 1 ATOM 8136 C CZ . PHE B 1 422 ? 35.150 16.662 28.794 1.00 2.00 ? 422 PHE B CZ 1 ATOM 8137 N N . GLN B 1 423 ? 35.132 21.649 27.204 1.00 2.66 ? 423 GLN B N 1 ATOM 8138 C CA . GLN B 1 423 ? 33.907 22.328 27.591 1.00 3.42 ? 423 GLN B CA 1 ATOM 8139 C C . GLN B 1 423 ? 33.074 21.252 28.252 1.00 3.99 ? 423 GLN B C 1 ATOM 8140 O O . GLN B 1 423 ? 32.876 20.176 27.685 1.00 3.76 ? 423 GLN B O 1 ATOM 8141 C CB . GLN B 1 423 ? 33.174 22.888 26.379 1.00 4.50 ? 423 GLN B CB 1 ATOM 8142 C CG . GLN B 1 423 ? 33.841 24.096 25.747 1.00 3.06 ? 423 GLN B CG 1 ATOM 8143 C CD . GLN B 1 423 ? 33.793 25.314 26.637 1.00 3.28 ? 423 GLN B CD 1 ATOM 8144 O OE1 . GLN B 1 423 ? 34.379 25.327 27.717 1.00 3.94 ? 423 GLN B OE1 1 ATOM 8145 N NE2 . GLN B 1 423 ? 33.087 26.350 26.189 1.00 4.72 ? 423 GLN B NE2 1 ATOM 8146 N N . PRO B 1 424 ? 32.551 21.541 29.449 1.00 6.05 ? 424 PRO B N 1 ATOM 8147 C CA . PRO B 1 424 ? 31.732 20.619 30.248 1.00 7.91 ? 424 PRO B CA 1 ATOM 8148 C C . PRO B 1 424 ? 30.546 20.025 29.498 1.00 7.97 ? 424 PRO B C 1 ATOM 8149 O O . PRO B 1 424 ? 30.056 18.945 29.833 1.00 7.97 ? 424 PRO B O 1 ATOM 8150 C CB . PRO B 1 424 ? 31.271 21.477 31.435 1.00 8.43 ? 424 PRO B CB 1 ATOM 8151 C CG . PRO B 1 424 ? 32.030 22.777 31.317 1.00 7.15 ? 424 PRO B CG 1 ATOM 8152 C CD . PRO B 1 424 ? 32.322 22.933 29.865 1.00 6.67 ? 424 PRO B CD 1 ATOM 8153 N N . THR B 1 425 ? 30.081 20.742 28.490 1.00 8.33 ? 425 THR B N 1 ATOM 8154 C CA . THR B 1 425 ? 28.952 20.281 27.710 1.00 11.71 ? 425 THR B CA 1 ATOM 8155 C C . THR B 1 425 ? 29.378 19.244 26.667 1.00 13.44 ? 425 THR B C 1 ATOM 8156 O O . THR B 1 425 ? 28.641 18.291 26.376 1.00 12.58 ? 425 THR B O 1 ATOM 8157 C CB . THR B 1 425 ? 28.276 21.483 27.010 1.00 13.25 ? 425 THR B CB 1 ATOM 8158 O OG1 . THR B 1 425 ? 27.695 22.337 28.002 1.00 14.68 ? 425 THR B OG1 1 ATOM 8159 C CG2 . THR B 1 425 ? 27.192 21.026 26.044 1.00 15.49 ? 425 THR B CG2 1 ATOM 8160 N N . HIS B 1 426 ? 30.584 19.403 26.135 1.00 13.54 ? 426 HIS B N 1 ATOM 8161 C CA . HIS B 1 426 ? 31.046 18.500 25.096 1.00 14.64 ? 426 HIS B CA 1 ATOM 8162 C C . HIS B 1 426 ? 32.049 17.421 25.457 1.00 14.35 ? 426 HIS B C 1 ATOM 8163 O O . HIS B 1 426 ? 32.515 17.339 26.590 1.00 13.95 ? 426 HIS B O 1 ATOM 8164 C CB . HIS B 1 426 ? 31.537 19.341 23.924 1.00 16.12 ? 426 HIS B CB 1 ATOM 8165 C CG . HIS B 1 426 ? 30.476 20.240 23.378 1.00 16.83 ? 426 HIS B CG 1 ATOM 8166 N ND1 . HIS B 1 426 ? 29.388 19.762 22.681 1.00 17.63 ? 426 HIS B ND1 1 ATOM 8167 C CD2 . HIS B 1 426 ? 30.276 21.571 23.523 1.00 16.94 ? 426 HIS B CD2 1 ATOM 8168 C CE1 . HIS B 1 426 ? 28.561 20.758 22.423 1.00 18.61 ? 426 HIS B CE1 1 ATOM 8169 N NE2 . HIS B 1 426 ? 29.076 21.866 22.924 1.00 19.29 ? 426 HIS B NE2 1 ATOM 8170 N N . LYS B 1 427 ? 32.364 16.590 24.467 1.00 13.81 ? 427 LYS B N 1 ATOM 8171 C CA . LYS B 1 427 ? 33.274 15.470 24.645 1.00 14.81 ? 427 LYS B CA 1 ATOM 8172 C C . LYS B 1 427 ? 34.737 15.683 24.237 1.00 13.16 ? 427 LYS B C 1 ATOM 8173 O O . LYS B 1 427 ? 35.639 15.151 24.880 1.00 14.15 ? 427 LYS B O 1 ATOM 8174 C CB . LYS B 1 427 ? 32.710 14.237 23.913 1.00 18.05 ? 427 LYS B CB 1 ATOM 8175 C CG . LYS B 1 427 ? 31.303 13.815 24.366 1.00 21.46 ? 427 LYS B CG 1 ATOM 8176 C CD . LYS B 1 427 ? 30.872 12.470 23.769 1.00 23.10 ? 427 LYS B CD 1 ATOM 8177 C CE . LYS B 1 427 ? 29.346 12.285 23.828 1.00 24.25 ? 427 LYS B CE 1 ATOM 8178 N NZ . LYS B 1 427 ? 28.617 13.221 22.907 1.00 24.31 ? 427 LYS B NZ 1 ATOM 8179 N N . ILE B 1 428 ? 34.989 16.447 23.181 1.00 10.82 ? 428 ILE B N 1 ATOM 8180 C CA . ILE B 1 428 ? 36.367 16.653 22.744 1.00 8.90 ? 428 ILE B CA 1 ATOM 8181 C C . ILE B 1 428 ? 37.173 17.646 23.564 1.00 7.71 ? 428 ILE B C 1 ATOM 8182 O O . ILE B 1 428 ? 36.624 18.480 24.279 1.00 8.01 ? 428 ILE B O 1 ATOM 8183 C CB . ILE B 1 428 ? 36.438 17.126 21.275 1.00 10.36 ? 428 ILE B CB 1 ATOM 8184 C CG1 . ILE B 1 428 ? 35.406 18.234 21.028 1.00 10.86 ? 428 ILE B CG1 1 ATOM 8185 C CG2 . ILE B 1 428 ? 36.239 15.943 20.339 1.00 12.40 ? 428 ILE B CG2 1 ATOM 8186 C CD1 . ILE B 1 428 ? 35.579 18.954 19.697 1.00 10.91 ? 428 ILE B CD1 1 ATOM 8187 N N . HIS B 1 429 ? 38.492 17.529 23.455 1.00 6.35 ? 429 HIS B N 1 ATOM 8188 C CA . HIS B 1 429 ? 39.428 18.433 24.121 1.00 5.38 ? 429 HIS B CA 1 ATOM 8189 C C . HIS B 1 429 ? 39.962 19.337 23.016 1.00 5.49 ? 429 HIS B C 1 ATOM 8190 O O . HIS B 1 429 ? 41.173 19.537 22.902 1.00 3.74 ? 429 HIS B O 1 ATOM 8191 C CB . HIS B 1 429 ? 40.615 17.672 24.700 1.00 4.47 ? 429 HIS B CB 1 ATOM 8192 C CG . HIS B 1 429 ? 40.449 17.273 26.127 1.00 3.25 ? 429 HIS B CG 1 ATOM 8193 N ND1 . HIS B 1 429 ? 39.489 16.379 26.543 1.00 2.54 ? 429 HIS B ND1 1 ATOM 8194 C CD2 . HIS B 1 429 ? 41.163 17.605 27.229 1.00 2.50 ? 429 HIS B CD2 1 ATOM 8195 C CE1 . HIS B 1 429 ? 39.621 16.171 27.841 1.00 3.74 ? 429 HIS B CE1 1 ATOM 8196 N NE2 . HIS B 1 429 ? 40.630 16.903 28.281 1.00 3.16 ? 429 HIS B NE2 1 ATOM 8197 N N . GLY B 1 430 ? 39.066 19.875 22.194 1.00 4.54 ? 430 GLY B N 1 ATOM 8198 C CA . GLY B 1 430 ? 39.527 20.709 21.102 1.00 4.12 ? 430 GLY B CA 1 ATOM 8199 C C . GLY B 1 430 ? 38.910 22.079 20.910 1.00 3.61 ? 430 GLY B C 1 ATOM 8200 O O . GLY B 1 430 ? 38.817 22.551 19.780 1.00 2.27 ? 430 GLY B O 1 ATOM 8201 N N . PHE B 1 431 ? 38.488 22.732 21.985 1.00 3.60 ? 431 PHE B N 1 ATOM 8202 C CA . PHE B 1 431 ? 37.916 24.057 21.830 1.00 3.71 ? 431 PHE B CA 1 ATOM 8203 C C . PHE B 1 431 ? 39.003 25.106 21.921 1.00 3.91 ? 431 PHE B C 1 ATOM 8204 O O . PHE B 1 431 ? 40.163 24.784 22.158 1.00 5.68 ? 431 PHE B O 1 ATOM 8205 C CB . PHE B 1 431 ? 36.843 24.317 22.877 1.00 4.43 ? 431 PHE B CB 1 ATOM 8206 C CG . PHE B 1 431 ? 35.513 23.713 22.533 1.00 6.28 ? 431 PHE B CG 1 ATOM 8207 C CD1 . PHE B 1 431 ? 35.093 22.525 23.122 1.00 6.89 ? 431 PHE B CD1 1 ATOM 8208 C CD2 . PHE B 1 431 ? 34.675 24.334 21.619 1.00 5.84 ? 431 PHE B CD2 1 ATOM 8209 C CE1 . PHE B 1 431 ? 33.853 21.969 22.806 1.00 7.15 ? 431 PHE B CE1 1 ATOM 8210 C CE2 . PHE B 1 431 ? 33.440 23.784 21.301 1.00 6.99 ? 431 PHE B CE2 1 ATOM 8211 C CZ . PHE B 1 431 ? 33.028 22.600 21.895 1.00 5.38 ? 431 PHE B CZ 1 ATOM 8212 N N . ASP B 1 432 ? 38.630 26.364 21.731 1.00 4.62 ? 432 ASP B N 1 ATOM 8213 C CA . ASP B 1 432 ? 39.599 27.455 21.775 1.00 4.79 ? 432 ASP B CA 1 ATOM 8214 C C . ASP B 1 432 ? 39.131 28.598 22.701 1.00 3.68 ? 432 ASP B C 1 ATOM 8215 O O . ASP B 1 432 ? 38.076 29.188 22.468 1.00 4.55 ? 432 ASP B O 1 ATOM 8216 C CB . ASP B 1 432 ? 39.818 27.962 20.341 1.00 2.78 ? 432 ASP B CB 1 ATOM 8217 C CG . ASP B 1 432 ? 40.754 29.150 20.269 1.00 3.37 ? 432 ASP B CG 1 ATOM 8218 O OD1 . ASP B 1 432 ? 41.175 29.658 21.330 1.00 5.25 ? 432 ASP B OD1 1 ATOM 8219 O OD2 . ASP B 1 432 ? 41.064 29.590 19.143 1.00 4.41 ? 432 ASP B OD2 1 ATOM 8220 N N . LEU B 1 433 ? 39.907 28.911 23.743 1.00 2.03 ? 433 LEU B N 1 ATOM 8221 C CA . LEU B 1 433 ? 39.526 29.988 24.660 1.00 2.32 ? 433 LEU B CA 1 ATOM 8222 C C . LEU B 1 433 ? 39.665 31.384 24.058 1.00 2.00 ? 433 LEU B C 1 ATOM 8223 O O . LEU B 1 433 ? 38.881 32.280 24.373 1.00 2.05 ? 433 LEU B O 1 ATOM 8224 C CB . LEU B 1 433 ? 40.329 29.921 25.965 1.00 2.00 ? 433 LEU B CB 1 ATOM 8225 C CG . LEU B 1 433 ? 39.984 31.012 26.992 1.00 2.00 ? 433 LEU B CG 1 ATOM 8226 C CD1 . LEU B 1 433 ? 38.479 31.141 27.148 1.00 2.00 ? 433 LEU B CD1 1 ATOM 8227 C CD2 . LEU B 1 433 ? 40.609 30.677 28.318 1.00 2.00 ? 433 LEU B CD2 1 ATOM 8228 N N . ALA B 1 434 ? 40.659 31.573 23.198 1.00 2.00 ? 434 ALA B N 1 ATOM 8229 C CA . ALA B 1 434 ? 40.873 32.867 22.562 1.00 2.00 ? 434 ALA B CA 1 ATOM 8230 C C . ALA B 1 434 ? 39.719 33.235 21.625 1.00 2.03 ? 434 ALA B C 1 ATOM 8231 O O . ALA B 1 434 ? 39.223 34.362 21.649 1.00 2.00 ? 434 ALA B O 1 ATOM 8232 C CB . ALA B 1 434 ? 42.182 32.852 21.790 1.00 2.00 ? 434 ALA B CB 1 ATOM 8233 N N . ALA B 1 435 ? 39.304 32.277 20.797 1.00 2.64 ? 435 ALA B N 1 ATOM 8234 C CA . ALA B 1 435 ? 38.214 32.481 19.846 1.00 2.00 ? 435 ALA B CA 1 ATOM 8235 C C . ALA B 1 435 ? 36.933 32.753 20.606 1.00 2.00 ? 435 ALA B C 1 ATOM 8236 O O . ALA B 1 435 ? 36.187 33.680 20.286 1.00 2.61 ? 435 ALA B O 1 ATOM 8237 C CB . ALA B 1 435 ? 38.046 31.249 18.961 1.00 2.00 ? 435 ALA B CB 1 ATOM 8238 N N . ILE B 1 436 ? 36.672 31.937 21.614 1.00 2.00 ? 436 ILE B N 1 ATOM 8239 C CA . ILE B 1 436 ? 35.480 32.139 22.408 1.00 2.00 ? 436 ILE B CA 1 ATOM 8240 C C . ILE B 1 436 ? 35.494 33.545 23.017 1.00 3.03 ? 436 ILE B C 1 ATOM 8241 O O . ILE B 1 436 ? 34.516 34.288 22.893 1.00 2.00 ? 436 ILE B O 1 ATOM 8242 C CB . ILE B 1 436 ? 35.386 31.119 23.541 1.00 2.12 ? 436 ILE B CB 1 ATOM 8243 C CG1 . ILE B 1 436 ? 35.326 29.708 22.965 1.00 2.47 ? 436 ILE B CG1 1 ATOM 8244 C CG2 . ILE B 1 436 ? 34.153 31.396 24.378 1.00 2.00 ? 436 ILE B CG2 1 ATOM 8245 C CD1 . ILE B 1 436 ? 35.157 28.638 24.014 1.00 2.67 ? 436 ILE B CD1 1 ATOM 8246 N N . ASN B 1 437 ? 36.601 33.909 23.669 1.00 2.57 ? 437 ASN B N 1 ATOM 8247 C CA . ASN B 1 437 ? 36.718 35.229 24.294 1.00 2.00 ? 437 ASN B CA 1 ATOM 8248 C C . ASN B 1 437 ? 36.391 36.331 23.306 1.00 3.49 ? 437 ASN B C 1 ATOM 8249 O O . ASN B 1 437 ? 35.940 37.408 23.698 1.00 2.74 ? 437 ASN B O 1 ATOM 8250 C CB . ASN B 1 437 ? 38.133 35.475 24.821 1.00 2.21 ? 437 ASN B CB 1 ATOM 8251 C CG . ASN B 1 437 ? 38.384 34.817 26.145 1.00 2.00 ? 437 ASN B CG 1 ATOM 8252 O OD1 . ASN B 1 437 ? 37.589 34.945 27.062 1.00 2.00 ? 437 ASN B OD1 1 ATOM 8253 N ND2 . ASN B 1 437 ? 39.501 34.119 26.260 1.00 2.76 ? 437 ASN B ND2 1 ATOM 8254 N N . LEU B 1 438 ? 36.629 36.052 22.024 1.00 4.57 ? 438 LEU B N 1 ATOM 8255 C CA . LEU B 1 438 ? 36.390 37.021 20.965 1.00 2.58 ? 438 LEU B CA 1 ATOM 8256 C C . LEU B 1 438 ? 34.973 37.130 20.458 1.00 2.29 ? 438 LEU B C 1 ATOM 8257 O O . LEU B 1 438 ? 34.500 38.237 20.230 1.00 2.66 ? 438 LEU B O 1 ATOM 8258 C CB . LEU B 1 438 ? 37.334 36.771 19.799 1.00 2.00 ? 438 LEU B CB 1 ATOM 8259 C CG . LEU B 1 438 ? 38.691 37.411 20.088 1.00 3.11 ? 438 LEU B CG 1 ATOM 8260 C CD1 . LEU B 1 438 ? 39.575 37.260 18.865 1.00 2.93 ? 438 LEU B CD1 1 ATOM 8261 C CD2 . LEU B 1 438 ? 38.509 38.893 20.450 1.00 2.00 ? 438 LEU B CD2 1 ATOM 8262 N N . GLN B 1 439 ? 34.280 36.020 20.249 1.00 2.70 ? 439 GLN B N 1 ATOM 8263 C CA . GLN B 1 439 ? 32.902 36.177 19.804 1.00 5.44 ? 439 GLN B CA 1 ATOM 8264 C C . GLN B 1 439 ? 32.078 36.640 21.003 1.00 4.91 ? 439 GLN B C 1 ATOM 8265 O O . GLN B 1 439 ? 31.206 37.506 20.874 1.00 4.24 ? 439 GLN B O 1 ATOM 8266 C CB . GLN B 1 439 ? 32.331 34.880 19.206 1.00 6.10 ? 439 GLN B CB 1 ATOM 8267 C CG . GLN B 1 439 ? 32.445 34.860 17.675 1.00 8.05 ? 439 GLN B CG 1 ATOM 8268 C CD . GLN B 1 439 ? 31.528 33.851 17.009 1.00 9.14 ? 439 GLN B CD 1 ATOM 8269 O OE1 . GLN B 1 439 ? 30.306 33.925 17.135 1.00 9.12 ? 439 GLN B OE1 1 ATOM 8270 N NE2 . GLN B 1 439 ? 32.117 32.901 16.289 1.00 9.95 ? 439 GLN B NE2 1 ATOM 8271 N N . ARG B 1 440 ? 32.395 36.084 22.171 1.00 3.38 ? 440 ARG B N 1 ATOM 8272 C CA . ARG B 1 440 ? 31.708 36.422 23.408 1.00 2.70 ? 440 ARG B CA 1 ATOM 8273 C C . ARG B 1 440 ? 31.715 37.929 23.620 1.00 2.51 ? 440 ARG B C 1 ATOM 8274 O O . ARG B 1 440 ? 30.857 38.464 24.322 1.00 3.95 ? 440 ARG B O 1 ATOM 8275 C CB . ARG B 1 440 ? 32.385 35.729 24.593 1.00 3.69 ? 440 ARG B CB 1 ATOM 8276 C CG . ARG B 1 440 ? 31.707 35.977 25.947 1.00 3.79 ? 440 ARG B CG 1 ATOM 8277 C CD . ARG B 1 440 ? 30.371 35.249 26.048 1.00 4.39 ? 440 ARG B CD 1 ATOM 8278 N NE . ARG B 1 440 ? 30.510 33.818 26.318 1.00 2.58 ? 440 ARG B NE 1 ATOM 8279 C CZ . ARG B 1 440 ? 29.661 32.899 25.871 1.00 2.00 ? 440 ARG B CZ 1 ATOM 8280 N NH1 . ARG B 1 440 ? 28.621 33.261 25.129 1.00 2.00 ? 440 ARG B NH1 1 ATOM 8281 N NH2 . ARG B 1 440 ? 29.846 31.624 26.167 1.00 2.00 ? 440 ARG B NH2 1 ATOM 8282 N N . CYS B 1 441 ? 32.700 38.608 23.038 1.00 2.00 ? 441 CYS B N 1 ATOM 8283 C CA . CYS B 1 441 ? 32.772 40.058 23.145 1.00 2.00 ? 441 CYS B CA 1 ATOM 8284 C C . CYS B 1 441 ? 31.609 40.558 22.322 1.00 2.00 ? 441 CYS B C 1 ATOM 8285 O O . CYS B 1 441 ? 30.778 41.337 22.780 1.00 2.00 ? 441 CYS B O 1 ATOM 8286 C CB . CYS B 1 441 ? 34.059 40.600 22.528 1.00 2.00 ? 441 CYS B CB 1 ATOM 8287 S SG . CYS B 1 441 ? 35.475 40.756 23.632 1.00 2.03 ? 441 CYS B SG 1 ATOM 8288 N N . ARG B 1 442 ? 31.554 40.079 21.090 1.00 2.99 ? 442 ARG B N 1 ATOM 8289 C CA . ARG B 1 442 ? 30.510 40.467 20.162 1.00 2.89 ? 442 ARG B CA 1 ATOM 8290 C C . ARG B 1 442 ? 29.112 40.122 20.679 1.00 2.00 ? 442 ARG B C 1 ATOM 8291 O O . ARG B 1 442 ? 28.184 40.913 20.521 1.00 2.00 ? 442 ARG B O 1 ATOM 8292 C CB . ARG B 1 442 ? 30.810 39.823 18.812 1.00 2.00 ? 442 ARG B CB 1 ATOM 8293 C CG . ARG B 1 442 ? 32.206 40.202 18.344 1.00 2.00 ? 442 ARG B CG 1 ATOM 8294 C CD . ARG B 1 442 ? 32.650 39.436 17.125 1.00 3.14 ? 442 ARG B CD 1 ATOM 8295 N NE . ARG B 1 442 ? 34.035 39.736 16.780 1.00 2.00 ? 442 ARG B NE 1 ATOM 8296 C CZ . ARG B 1 442 ? 34.639 39.296 15.688 1.00 2.00 ? 442 ARG B CZ 1 ATOM 8297 N NH1 . ARG B 1 442 ? 33.985 38.537 14.829 1.00 2.00 ? 442 ARG B NH1 1 ATOM 8298 N NH2 . ARG B 1 442 ? 35.895 39.620 15.458 1.00 2.00 ? 442 ARG B NH2 1 ATOM 8299 N N . ASP B 1 443 ? 28.975 38.956 21.308 1.00 2.00 ? 443 ASP B N 1 ATOM 8300 C CA . ASP B 1 443 ? 27.697 38.508 21.880 1.00 2.70 ? 443 ASP B CA 1 ATOM 8301 C C . ASP B 1 443 ? 27.186 39.576 22.862 1.00 2.71 ? 443 ASP B C 1 ATOM 8302 O O . ASP B 1 443 ? 26.028 40.004 22.795 1.00 2.15 ? 443 ASP B O 1 ATOM 8303 C CB . ASP B 1 443 ? 27.899 37.149 22.596 1.00 2.00 ? 443 ASP B CB 1 ATOM 8304 C CG . ASP B 1 443 ? 26.606 36.569 23.211 1.00 2.00 ? 443 ASP B CG 1 ATOM 8305 O OD1 . ASP B 1 443 ? 25.484 37.052 22.928 1.00 2.00 ? 443 ASP B OD1 1 ATOM 8306 O OD2 . ASP B 1 443 ? 26.727 35.593 23.988 1.00 2.00 ? 443 ASP B OD2 1 ATOM 8307 N N . HIS B 1 444 ? 28.063 40.022 23.755 1.00 2.00 ? 444 HIS B N 1 ATOM 8308 C CA . HIS B 1 444 ? 27.703 41.030 24.743 1.00 2.00 ? 444 HIS B CA 1 ATOM 8309 C C . HIS B 1 444 ? 27.551 42.430 24.165 1.00 2.00 ? 444 HIS B C 1 ATOM 8310 O O . HIS B 1 444 ? 27.052 43.327 24.835 1.00 2.64 ? 444 HIS B O 1 ATOM 8311 C CB . HIS B 1 444 ? 28.728 41.034 25.873 1.00 2.36 ? 444 HIS B CB 1 ATOM 8312 C CG . HIS B 1 444 ? 28.614 39.853 26.779 1.00 2.41 ? 444 HIS B CG 1 ATOM 8313 N ND1 . HIS B 1 444 ? 28.035 39.926 28.027 1.00 2.57 ? 444 HIS B ND1 1 ATOM 8314 C CD2 . HIS B 1 444 ? 28.936 38.553 26.588 1.00 2.45 ? 444 HIS B CD2 1 ATOM 8315 C CE1 . HIS B 1 444 ? 28.001 38.720 28.565 1.00 3.22 ? 444 HIS B CE1 1 ATOM 8316 N NE2 . HIS B 1 444 ? 28.539 37.869 27.712 1.00 4.45 ? 444 HIS B NE2 1 ATOM 8317 N N . GLY B 1 445 ? 27.996 42.624 22.930 1.00 2.34 ? 445 GLY B N 1 ATOM 8318 C CA . GLY B 1 445 ? 27.842 43.924 22.297 1.00 2.52 ? 445 GLY B CA 1 ATOM 8319 C C . GLY B 1 445 ? 28.858 45.008 22.584 1.00 2.00 ? 445 GLY B C 1 ATOM 8320 O O . GLY B 1 445 ? 28.618 46.173 22.281 1.00 2.00 ? 445 GLY B O 1 ATOM 8321 N N . MET B 1 446 ? 29.993 44.636 23.156 1.00 2.00 ? 446 MET B N 1 ATOM 8322 C CA . MET B 1 446 ? 31.032 45.604 23.461 1.00 2.00 ? 446 MET B CA 1 ATOM 8323 C C . MET B 1 446 ? 31.317 46.530 22.290 1.00 2.27 ? 446 MET B C 1 ATOM 8324 O O . MET B 1 446 ? 31.157 46.154 21.133 1.00 3.54 ? 446 MET B O 1 ATOM 8325 C CB . MET B 1 446 ? 32.325 44.888 23.818 1.00 2.00 ? 446 MET B CB 1 ATOM 8326 C CG . MET B 1 446 ? 32.202 43.951 24.985 1.00 2.00 ? 446 MET B CG 1 ATOM 8327 S SD . MET B 1 446 ? 31.796 44.825 26.500 1.00 2.00 ? 446 MET B SD 1 ATOM 8328 C CE . MET B 1 446 ? 33.238 45.857 26.621 1.00 2.59 ? 446 MET B CE 1 ATOM 8329 N N . PRO B 1 447 ? 31.698 47.777 22.584 1.00 2.00 ? 447 PRO B N 1 ATOM 8330 C CA . PRO B 1 447 ? 32.025 48.762 21.555 1.00 2.00 ? 447 PRO B CA 1 ATOM 8331 C C . PRO B 1 447 ? 33.468 48.411 21.206 1.00 2.53 ? 447 PRO B C 1 ATOM 8332 O O . PRO B 1 447 ? 33.999 47.439 21.734 1.00 4.21 ? 447 PRO B O 1 ATOM 8333 C CB . PRO B 1 447 ? 31.932 50.084 22.300 1.00 2.00 ? 447 PRO B CB 1 ATOM 8334 C CG . PRO B 1 447 ? 30.959 49.791 23.396 1.00 2.00 ? 447 PRO B CG 1 ATOM 8335 C CD . PRO B 1 447 ? 31.405 48.445 23.859 1.00 2.46 ? 447 PRO B CD 1 ATOM 8336 N N . GLY B 1 448 ? 34.118 49.196 20.357 1.00 2.84 ? 448 GLY B N 1 ATOM 8337 C CA . GLY B 1 448 ? 35.487 48.876 19.984 1.00 2.00 ? 448 GLY B CA 1 ATOM 8338 C C . GLY B 1 448 ? 36.624 49.368 20.864 1.00 2.00 ? 448 GLY B C 1 ATOM 8339 O O . GLY B 1 448 ? 36.427 49.998 21.897 1.00 2.00 ? 448 GLY B O 1 ATOM 8340 N N . TYR B 1 449 ? 37.836 49.055 20.434 1.00 2.00 ? 449 TYR B N 1 ATOM 8341 C CA . TYR B 1 449 ? 39.053 49.454 21.124 1.00 2.00 ? 449 TYR B CA 1 ATOM 8342 C C . TYR B 1 449 ? 39.099 50.980 21.281 1.00 3.10 ? 449 TYR B C 1 ATOM 8343 O O . TYR B 1 449 ? 39.323 51.494 22.373 1.00 2.00 ? 449 TYR B O 1 ATOM 8344 C CB . TYR B 1 449 ? 40.252 48.963 20.307 1.00 2.26 ? 449 TYR B CB 1 ATOM 8345 C CG . TYR B 1 449 ? 41.621 49.366 20.804 1.00 2.00 ? 449 TYR B CG 1 ATOM 8346 C CD1 . TYR B 1 449 ? 42.147 48.838 21.984 1.00 2.97 ? 449 TYR B CD1 1 ATOM 8347 C CD2 . TYR B 1 449 ? 42.411 50.246 20.070 1.00 2.00 ? 449 TYR B CD2 1 ATOM 8348 C CE1 . TYR B 1 449 ? 43.431 49.179 22.416 1.00 2.74 ? 449 TYR B CE1 1 ATOM 8349 C CE2 . TYR B 1 449 ? 43.690 50.590 20.494 1.00 2.00 ? 449 TYR B CE2 1 ATOM 8350 C CZ . TYR B 1 449 ? 44.192 50.055 21.665 1.00 2.00 ? 449 TYR B CZ 1 ATOM 8351 O OH . TYR B 1 449 ? 45.445 50.414 22.091 1.00 2.00 ? 449 TYR B OH 1 ATOM 8352 N N . ASN B 1 450 ? 38.878 51.704 20.186 1.00 3.36 ? 450 ASN B N 1 ATOM 8353 C CA . ASN B 1 450 ? 38.914 53.157 20.237 1.00 3.28 ? 450 ASN B CA 1 ATOM 8354 C C . ASN B 1 450 ? 37.861 53.765 21.143 1.00 4.75 ? 450 ASN B C 1 ATOM 8355 O O . ASN B 1 450 ? 38.162 54.640 21.961 1.00 5.35 ? 450 ASN B O 1 ATOM 8356 C CB . ASN B 1 450 ? 38.782 53.754 18.838 1.00 4.22 ? 450 ASN B CB 1 ATOM 8357 C CG . ASN B 1 450 ? 40.117 53.886 18.146 1.00 6.72 ? 450 ASN B CG 1 ATOM 8358 O OD1 . ASN B 1 450 ? 41.106 54.262 18.770 1.00 8.78 ? 450 ASN B OD1 1 ATOM 8359 N ND2 . ASN B 1 450 ? 40.156 53.590 16.850 1.00 9.01 ? 450 ASN B ND2 1 ATOM 8360 N N . SER B 1 451 ? 36.623 53.318 21.016 1.00 2.63 ? 451 SER B N 1 ATOM 8361 C CA . SER B 1 451 ? 35.604 53.895 21.862 1.00 3.25 ? 451 SER B CA 1 ATOM 8362 C C . SER B 1 451 ? 35.893 53.649 23.346 1.00 4.06 ? 451 SER B C 1 ATOM 8363 O O . SER B 1 451 ? 35.273 54.262 24.216 1.00 5.24 ? 451 SER B O 1 ATOM 8364 C CB . SER B 1 451 ? 34.233 53.359 21.474 1.00 2.76 ? 451 SER B CB 1 ATOM 8365 O OG . SER B 1 451 ? 33.387 54.452 21.163 1.00 7.88 ? 451 SER B OG 1 ATOM 8366 N N . TRP B 1 452 ? 36.841 52.760 23.635 1.00 3.25 ? 452 TRP B N 1 ATOM 8367 C CA . TRP B 1 452 ? 37.210 52.463 25.017 1.00 2.00 ? 452 TRP B CA 1 ATOM 8368 C C . TRP B 1 452 ? 38.463 53.230 25.375 1.00 2.00 ? 452 TRP B C 1 ATOM 8369 O O . TRP B 1 452 ? 38.621 53.676 26.501 1.00 2.00 ? 452 TRP B O 1 ATOM 8370 C CB . TRP B 1 452 ? 37.451 50.970 25.210 1.00 2.53 ? 452 TRP B CB 1 ATOM 8371 C CG . TRP B 1 452 ? 36.194 50.180 25.319 1.00 2.06 ? 452 TRP B CG 1 ATOM 8372 C CD1 . TRP B 1 452 ? 35.762 49.197 24.478 1.00 2.00 ? 452 TRP B CD1 1 ATOM 8373 C CD2 . TRP B 1 452 ? 35.208 50.294 26.346 1.00 2.58 ? 452 TRP B CD2 1 ATOM 8374 N NE1 . TRP B 1 452 ? 34.571 48.691 24.920 1.00 2.00 ? 452 TRP B NE1 1 ATOM 8375 C CE2 . TRP B 1 452 ? 34.206 49.347 26.067 1.00 2.13 ? 452 TRP B CE2 1 ATOM 8376 C CE3 . TRP B 1 452 ? 35.074 51.108 27.480 1.00 2.18 ? 452 TRP B CE3 1 ATOM 8377 C CZ2 . TRP B 1 452 ? 33.078 49.189 26.882 1.00 2.01 ? 452 TRP B CZ2 1 ATOM 8378 C CZ3 . TRP B 1 452 ? 33.952 50.948 28.290 1.00 2.09 ? 452 TRP B CZ3 1 ATOM 8379 C CH2 . TRP B 1 452 ? 32.971 49.996 27.985 1.00 2.00 ? 452 TRP B CH2 1 ATOM 8380 N N . ARG B 1 453 ? 39.371 53.360 24.416 1.00 2.43 ? 453 ARG B N 1 ATOM 8381 C CA . ARG B 1 453 ? 40.588 54.126 24.651 1.00 2.72 ? 453 ARG B CA 1 ATOM 8382 C C . ARG B 1 453 ? 40.056 55.508 25.010 1.00 2.00 ? 453 ARG B C 1 ATOM 8383 O O . ARG B 1 453 ? 40.667 56.242 25.784 1.00 2.00 ? 453 ARG B O 1 ATOM 8384 C CB . ARG B 1 453 ? 41.438 54.214 23.372 1.00 2.57 ? 453 ARG B CB 1 ATOM 8385 C CG . ARG B 1 453 ? 42.270 52.974 23.030 1.00 2.10 ? 453 ARG B CG 1 ATOM 8386 C CD . ARG B 1 453 ? 43.641 52.988 23.727 1.00 3.65 ? 453 ARG B CD 1 ATOM 8387 N NE . ARG B 1 453 ? 44.332 54.270 23.540 1.00 5.36 ? 453 ARG B NE 1 ATOM 8388 C CZ . ARG B 1 453 ? 45.642 54.467 23.697 1.00 4.14 ? 453 ARG B CZ 1 ATOM 8389 N NH1 . ARG B 1 453 ? 46.435 53.464 24.046 1.00 5.11 ? 453 ARG B NH1 1 ATOM 8390 N NH2 . ARG B 1 453 ? 46.165 55.673 23.502 1.00 2.66 ? 453 ARG B NH2 1 ATOM 8391 N N . GLY B 1 454 ? 38.899 55.842 24.438 1.00 2.00 ? 454 GLY B N 1 ATOM 8392 C CA . GLY B 1 454 ? 38.284 57.126 24.701 1.00 2.22 ? 454 GLY B CA 1 ATOM 8393 C C . GLY B 1 454 ? 37.814 57.190 26.138 1.00 2.62 ? 454 GLY B C 1 ATOM 8394 O O . GLY B 1 454 ? 38.285 58.007 26.925 1.00 2.95 ? 454 GLY B O 1 ATOM 8395 N N . PHE B 1 455 ? 36.880 56.313 26.480 1.00 2.71 ? 455 PHE B N 1 ATOM 8396 C CA . PHE B 1 455 ? 36.333 56.247 27.828 1.00 2.22 ? 455 PHE B CA 1 ATOM 8397 C C . PHE B 1 455 ? 37.381 56.536 28.897 1.00 2.00 ? 455 PHE B C 1 ATOM 8398 O O . PHE B 1 455 ? 37.045 57.020 29.975 1.00 2.38 ? 455 PHE B O 1 ATOM 8399 C CB . PHE B 1 455 ? 35.740 54.857 28.071 1.00 2.63 ? 455 PHE B CB 1 ATOM 8400 C CG . PHE B 1 455 ? 35.246 54.649 29.464 1.00 2.00 ? 455 PHE B CG 1 ATOM 8401 C CD1 . PHE B 1 455 ? 34.019 55.166 29.862 1.00 2.00 ? 455 PHE B CD1 1 ATOM 8402 C CD2 . PHE B 1 455 ? 36.019 53.954 30.386 1.00 2.00 ? 455 PHE B CD2 1 ATOM 8403 C CE1 . PHE B 1 455 ? 33.562 54.998 31.155 1.00 2.14 ? 455 PHE B CE1 1 ATOM 8404 C CE2 . PHE B 1 455 ? 35.573 53.780 31.684 1.00 3.40 ? 455 PHE B CE2 1 ATOM 8405 C CZ . PHE B 1 455 ? 34.338 54.304 32.070 1.00 3.57 ? 455 PHE B CZ 1 ATOM 8406 N N . CYS B 1 456 ? 38.644 56.242 28.593 1.00 2.00 ? 456 CYS B N 1 ATOM 8407 C CA . CYS B 1 456 ? 39.732 56.443 29.548 1.00 2.56 ? 456 CYS B CA 1 ATOM 8408 C C . CYS B 1 456 ? 40.581 57.707 29.372 1.00 3.20 ? 456 CYS B C 1 ATOM 8409 O O . CYS B 1 456 ? 41.188 58.177 30.331 1.00 3.61 ? 456 CYS B O 1 ATOM 8410 C CB . CYS B 1 456 ? 40.634 55.199 29.578 1.00 2.00 ? 456 CYS B CB 1 ATOM 8411 S SG . CYS B 1 456 ? 39.798 53.708 30.225 1.00 2.16 ? 456 CYS B SG 1 ATOM 8412 N N . GLY B 1 457 ? 40.628 58.266 28.169 1.00 2.69 ? 457 GLY B N 1 ATOM 8413 C CA . GLY B 1 457 ? 41.412 59.475 27.975 1.00 3.01 ? 457 GLY B CA 1 ATOM 8414 C C . GLY B 1 457 ? 42.766 59.237 27.337 1.00 4.44 ? 457 GLY B C 1 ATOM 8415 O O . GLY B 1 457 ? 43.777 59.848 27.710 1.00 4.25 ? 457 GLY B O 1 ATOM 8416 N N . LEU B 1 458 ? 42.772 58.330 26.368 1.00 4.71 ? 458 LEU B N 1 ATOM 8417 C CA . LEU B 1 458 ? 43.967 57.969 25.625 1.00 5.46 ? 458 LEU B CA 1 ATOM 8418 C C . LEU B 1 458 ? 43.639 58.213 24.169 1.00 7.37 ? 458 LEU B C 1 ATOM 8419 O O . LEU B 1 458 ? 42.474 58.150 23.792 1.00 9.21 ? 458 LEU B O 1 ATOM 8420 C CB . LEU B 1 458 ? 44.303 56.500 25.851 1.00 4.16 ? 458 LEU B CB 1 ATOM 8421 C CG . LEU B 1 458 ? 44.825 56.214 27.258 1.00 3.97 ? 458 LEU B CG 1 ATOM 8422 C CD1 . LEU B 1 458 ? 43.696 56.033 28.270 1.00 3.52 ? 458 LEU B CD1 1 ATOM 8423 C CD2 . LEU B 1 458 ? 45.654 54.970 27.175 1.00 4.41 ? 458 LEU B CD2 1 ATOM 8424 N N . SER B 1 459 ? 44.653 58.490 23.354 1.00 8.13 ? 459 SER B N 1 ATOM 8425 C CA . SER B 1 459 ? 44.436 58.766 21.935 1.00 8.28 ? 459 SER B CA 1 ATOM 8426 C C . SER B 1 459 ? 43.781 57.603 21.203 1.00 8.85 ? 459 SER B C 1 ATOM 8427 O O . SER B 1 459 ? 44.125 56.443 21.427 1.00 9.04 ? 459 SER B O 1 ATOM 8428 C CB . SER B 1 459 ? 45.758 59.080 21.249 1.00 8.81 ? 459 SER B CB 1 ATOM 8429 O OG . SER B 1 459 ? 46.464 57.880 20.986 1.00 11.28 ? 459 SER B OG 1 ATOM 8430 N N . GLN B 1 460 ? 42.842 57.923 20.319 1.00 9.81 ? 460 GLN B N 1 ATOM 8431 C CA . GLN B 1 460 ? 42.150 56.906 19.532 1.00 10.25 ? 460 GLN B CA 1 ATOM 8432 C C . GLN B 1 460 ? 42.857 56.827 18.153 1.00 10.12 ? 460 GLN B C 1 ATOM 8433 O O . GLN B 1 460 ? 42.443 57.468 17.186 1.00 10.42 ? 460 GLN B O 1 ATOM 8434 C CB . GLN B 1 460 ? 40.667 57.294 19.381 1.00 9.58 ? 460 GLN B CB 1 ATOM 8435 C CG . GLN B 1 460 ? 40.048 57.929 20.636 1.00 8.90 ? 460 GLN B CG 1 ATOM 8436 C CD . GLN B 1 460 ? 38.567 58.278 20.480 1.00 9.64 ? 460 GLN B CD 1 ATOM 8437 O OE1 . GLN B 1 460 ? 37.706 57.406 20.517 1.00 10.95 ? 460 GLN B OE1 1 ATOM 8438 N NE2 . GLN B 1 460 ? 38.273 59.559 20.299 1.00 9.60 ? 460 GLN B NE2 1 ATOM 8439 N N . PRO B 1 461 ? 43.927 56.019 18.053 1.00 8.32 ? 461 PRO B N 1 ATOM 8440 C CA . PRO B 1 461 ? 44.674 55.882 16.805 1.00 8.09 ? 461 PRO B CA 1 ATOM 8441 C C . PRO B 1 461 ? 43.799 55.406 15.682 1.00 9.38 ? 461 PRO B C 1 ATOM 8442 O O . PRO B 1 461 ? 42.853 54.659 15.908 1.00 7.77 ? 461 PRO B O 1 ATOM 8443 C CB . PRO B 1 461 ? 45.733 54.862 17.160 1.00 8.62 ? 461 PRO B CB 1 ATOM 8444 C CG . PRO B 1 461 ? 44.962 53.941 18.011 1.00 9.30 ? 461 PRO B CG 1 ATOM 8445 C CD . PRO B 1 461 ? 44.258 54.902 18.951 1.00 8.99 ? 461 PRO B CD 1 ATOM 8446 N N . LYS B 1 462 ? 44.134 55.849 14.473 1.00 11.56 ? 462 LYS B N 1 ATOM 8447 C CA . LYS B 1 462 ? 43.400 55.494 13.264 1.00 14.10 ? 462 LYS B CA 1 ATOM 8448 C C . LYS B 1 462 ? 44.397 55.055 12.179 1.00 15.06 ? 462 LYS B C 1 ATOM 8449 O O . LYS B 1 462 ? 44.133 54.125 11.408 1.00 15.01 ? 462 LYS B O 1 ATOM 8450 C CB . LYS B 1 462 ? 42.563 56.696 12.791 1.00 14.62 ? 462 LYS B CB 1 ATOM 8451 C CG . LYS B 1 462 ? 42.177 57.661 13.923 1.00 16.13 ? 462 LYS B CG 1 ATOM 8452 C CD . LYS B 1 462 ? 40.788 58.290 13.755 1.00 17.71 ? 462 LYS B CD 1 ATOM 8453 C CE . LYS B 1 462 ? 39.678 57.454 14.428 1.00 18.68 ? 462 LYS B CE 1 ATOM 8454 N NZ . LYS B 1 462 ? 38.986 56.482 13.521 1.00 19.69 ? 462 LYS B NZ 1 ATOM 8455 N N . THR B 1 463 ? 45.551 55.714 12.131 1.00 15.05 ? 463 THR B N 1 ATOM 8456 C CA . THR B 1 463 ? 46.571 55.362 11.153 1.00 15.15 ? 463 THR B CA 1 ATOM 8457 C C . THR B 1 463 ? 47.316 54.123 11.625 1.00 15.50 ? 463 THR B C 1 ATOM 8458 O O . THR B 1 463 ? 47.489 53.915 12.825 1.00 16.37 ? 463 THR B O 1 ATOM 8459 C CB . THR B 1 463 ? 47.577 56.514 10.944 1.00 15.17 ? 463 THR B CB 1 ATOM 8460 O OG1 . THR B 1 463 ? 48.075 56.966 12.209 1.00 13.92 ? 463 THR B OG1 1 ATOM 8461 C CG2 . THR B 1 463 ? 46.906 57.670 10.234 1.00 15.77 ? 463 THR B CG2 1 ATOM 8462 N N . LEU B 1 464 ? 47.734 53.287 10.681 1.00 15.42 ? 464 LEU B N 1 ATOM 8463 C CA . LEU B 1 464 ? 48.463 52.076 11.016 1.00 13.78 ? 464 LEU B CA 1 ATOM 8464 C C . LEU B 1 464 ? 49.762 52.514 11.669 1.00 14.00 ? 464 LEU B C 1 ATOM 8465 O O . LEU B 1 464 ? 50.335 51.792 12.478 1.00 14.36 ? 464 LEU B O 1 ATOM 8466 C CB . LEU B 1 464 ? 48.678 51.234 9.744 1.00 13.53 ? 464 LEU B CB 1 ATOM 8467 C CG . LEU B 1 464 ? 49.900 50.393 9.343 1.00 13.64 ? 464 LEU B CG 1 ATOM 8468 C CD1 . LEU B 1 464 ? 50.794 51.247 8.465 1.00 13.88 ? 464 LEU B CD1 1 ATOM 8469 C CD2 . LEU B 1 464 ? 50.651 49.840 10.545 1.00 14.44 ? 464 LEU B CD2 1 ATOM 8470 N N . LYS B 1 465 ? 50.208 53.721 11.342 1.00 15.32 ? 465 LYS B N 1 ATOM 8471 C CA . LYS B 1 465 ? 51.427 54.246 11.941 1.00 17.85 ? 465 LYS B CA 1 ATOM 8472 C C . LYS B 1 465 ? 51.032 54.705 13.337 1.00 15.97 ? 465 LYS B C 1 ATOM 8473 O O . LYS B 1 465 ? 51.867 54.841 14.230 1.00 15.75 ? 465 LYS B O 1 ATOM 8474 C CB . LYS B 1 465 ? 51.968 55.424 11.125 1.00 21.88 ? 465 LYS B CB 1 ATOM 8475 C CG . LYS B 1 465 ? 53.496 55.467 11.050 1.00 28.32 ? 465 LYS B CG 1 ATOM 8476 C CD . LYS B 1 465 ? 53.983 56.244 9.821 1.00 31.55 ? 465 LYS B CD 1 ATOM 8477 C CE . LYS B 1 465 ? 55.395 55.807 9.414 1.00 33.09 ? 465 LYS B CE 1 ATOM 8478 N NZ . LYS B 1 465 ? 56.412 56.894 9.537 1.00 35.21 ? 465 LYS B NZ 1 ATOM 8479 N N . GLY B 1 466 ? 49.736 54.933 13.511 1.00 15.07 ? 466 GLY B N 1 ATOM 8480 C CA . GLY B 1 466 ? 49.223 55.364 14.796 1.00 13.75 ? 466 GLY B CA 1 ATOM 8481 C C . GLY B 1 466 ? 49.115 54.200 15.763 1.00 12.22 ? 466 GLY B C 1 ATOM 8482 O O . GLY B 1 466 ? 49.488 54.320 16.936 1.00 12.25 ? 466 GLY B O 1 ATOM 8483 N N . LEU B 1 467 ? 48.604 53.070 15.279 1.00 9.18 ? 467 LEU B N 1 ATOM 8484 C CA . LEU B 1 467 ? 48.469 51.906 16.133 1.00 6.78 ? 467 LEU B CA 1 ATOM 8485 C C . LEU B 1 467 ? 49.860 51.535 16.634 1.00 10.04 ? 467 LEU B C 1 ATOM 8486 O O . LEU B 1 467 ? 50.034 51.118 17.788 1.00 9.90 ? 467 LEU B O 1 ATOM 8487 C CB . LEU B 1 467 ? 47.870 50.731 15.368 1.00 4.17 ? 467 LEU B CB 1 ATOM 8488 C CG . LEU B 1 467 ? 47.477 49.583 16.303 1.00 2.91 ? 467 LEU B CG 1 ATOM 8489 C CD1 . LEU B 1 467 ? 46.070 49.797 16.845 1.00 2.00 ? 467 LEU B CD1 1 ATOM 8490 C CD2 . LEU B 1 467 ? 47.534 48.286 15.558 1.00 2.46 ? 467 LEU B CD2 1 ATOM 8491 N N . GLN B 1 468 ? 50.854 51.706 15.764 1.00 9.13 ? 468 GLN B N 1 ATOM 8492 C CA . GLN B 1 468 ? 52.235 51.391 16.107 1.00 8.96 ? 468 GLN B CA 1 ATOM 8493 C C . GLN B 1 468 ? 52.742 52.204 17.291 1.00 8.01 ? 468 GLN B C 1 ATOM 8494 O O . GLN B 1 468 ? 53.435 51.682 18.165 1.00 5.45 ? 468 GLN B O 1 ATOM 8495 C CB . GLN B 1 468 ? 53.128 51.602 14.893 1.00 12.57 ? 468 GLN B CB 1 ATOM 8496 C CG . GLN B 1 468 ? 52.890 50.551 13.830 1.00 17.00 ? 468 GLN B CG 1 ATOM 8497 C CD . GLN B 1 468 ? 53.851 50.656 12.672 1.00 19.49 ? 468 GLN B CD 1 ATOM 8498 O OE1 . GLN B 1 468 ? 53.888 49.775 11.804 1.00 21.31 ? 468 GLN B OE1 1 ATOM 8499 N NE2 . GLN B 1 468 ? 54.638 51.735 12.644 1.00 20.46 ? 468 GLN B NE2 1 ATOM 8500 N N . ALA B 1 469 ? 52.387 53.481 17.322 1.00 7.52 ? 469 ALA B N 1 ATOM 8501 C CA . ALA B 1 469 ? 52.792 54.338 18.424 1.00 7.43 ? 469 ALA B CA 1 ATOM 8502 C C . ALA B 1 469 ? 52.328 53.727 19.747 1.00 6.48 ? 469 ALA B C 1 ATOM 8503 O O . ALA B 1 469 ? 53.127 53.578 20.670 1.00 8.15 ? 469 ALA B O 1 ATOM 8504 C CB . ALA B 1 469 ? 52.200 55.728 18.251 1.00 6.36 ? 469 ALA B CB 1 ATOM 8505 N N . VAL B 1 470 ? 51.045 53.364 19.827 1.00 5.85 ? 470 VAL B N 1 ATOM 8506 C CA . VAL B 1 470 ? 50.461 52.774 21.047 1.00 7.30 ? 470 VAL B CA 1 ATOM 8507 C C . VAL B 1 470 ? 51.005 51.381 21.393 1.00 4.26 ? 470 VAL B C 1 ATOM 8508 O O . VAL B 1 470 ? 51.525 51.151 22.504 1.00 2.00 ? 470 VAL B O 1 ATOM 8509 C CB . VAL B 1 470 ? 48.886 52.686 20.949 1.00 5.59 ? 470 VAL B CB 1 ATOM 8510 C CG1 . VAL B 1 470 ? 48.347 51.636 21.900 1.00 4.51 ? 470 VAL B CG1 1 ATOM 8511 C CG2 . VAL B 1 470 ? 48.256 54.019 21.323 1.00 5.94 ? 470 VAL B CG2 1 ATOM 8512 N N . LEU B 1 471 ? 50.872 50.463 20.436 1.00 3.38 ? 471 LEU B N 1 ATOM 8513 C CA . LEU B 1 471 ? 51.320 49.085 20.612 1.00 4.34 ? 471 LEU B CA 1 ATOM 8514 C C . LEU B 1 471 ? 52.832 48.940 20.678 1.00 5.23 ? 471 LEU B C 1 ATOM 8515 O O . LEU B 1 471 ? 53.344 47.921 21.143 1.00 2.79 ? 471 LEU B O 1 ATOM 8516 C CB . LEU B 1 471 ? 50.761 48.210 19.493 1.00 2.00 ? 471 LEU B CB 1 ATOM 8517 C CG . LEU B 1 471 ? 49.539 47.383 19.879 1.00 2.00 ? 471 LEU B CG 1 ATOM 8518 C CD1 . LEU B 1 471 ? 48.933 47.881 21.176 1.00 2.00 ? 471 LEU B CD1 1 ATOM 8519 C CD2 . LEU B 1 471 ? 48.541 47.453 18.756 1.00 2.66 ? 471 LEU B CD2 1 ATOM 8520 N N . LYS B 1 472 ? 53.538 49.968 20.217 1.00 6.26 ? 472 LYS B N 1 ATOM 8521 C CA . LYS B 1 472 ? 54.991 49.966 20.227 1.00 5.81 ? 472 LYS B CA 1 ATOM 8522 C C . LYS B 1 472 ? 55.469 48.645 19.638 1.00 6.24 ? 472 LYS B C 1 ATOM 8523 O O . LYS B 1 472 ? 56.118 47.850 20.319 1.00 6.72 ? 472 LYS B O 1 ATOM 8524 C CB . LYS B 1 472 ? 55.480 50.117 21.660 1.00 8.15 ? 472 LYS B CB 1 ATOM 8525 C CG . LYS B 1 472 ? 56.836 50.745 21.784 1.00 12.40 ? 472 LYS B CG 1 ATOM 8526 C CD . LYS B 1 472 ? 56.825 51.693 22.954 1.00 17.21 ? 472 LYS B CD 1 ATOM 8527 C CE . LYS B 1 472 ? 55.793 52.782 22.707 1.00 20.92 ? 472 LYS B CE 1 ATOM 8528 N NZ . LYS B 1 472 ? 55.632 53.711 23.863 1.00 26.72 ? 472 LYS B NZ 1 ATOM 8529 N N . ASN B 1 473 ? 55.130 48.423 18.370 1.00 6.14 ? 473 ASN B N 1 ATOM 8530 C CA . ASN B 1 473 ? 55.481 47.198 17.649 1.00 6.99 ? 473 ASN B CA 1 ATOM 8531 C C . ASN B 1 473 ? 54.807 47.230 16.273 1.00 8.07 ? 473 ASN B C 1 ATOM 8532 O O . ASN B 1 473 ? 53.579 47.261 16.187 1.00 8.71 ? 473 ASN B O 1 ATOM 8533 C CB . ASN B 1 473 ? 54.986 45.978 18.436 1.00 5.03 ? 473 ASN B CB 1 ATOM 8534 C CG . ASN B 1 473 ? 55.127 44.686 17.663 1.00 4.81 ? 473 ASN B CG 1 ATOM 8535 O OD1 . ASN B 1 473 ? 54.652 44.565 16.529 1.00 2.44 ? 473 ASN B OD1 1 ATOM 8536 N ND2 . ASN B 1 473 ? 55.773 43.701 18.282 1.00 5.11 ? 473 ASN B ND2 1 ATOM 8537 N N . LYS B 1 474 ? 55.596 47.211 15.200 1.00 9.55 ? 474 LYS B N 1 ATOM 8538 C CA . LYS B 1 474 ? 55.024 47.258 13.853 1.00 11.21 ? 474 LYS B CA 1 ATOM 8539 C C . LYS B 1 474 ? 54.275 46.000 13.400 1.00 11.10 ? 474 LYS B C 1 ATOM 8540 O O . LYS B 1 474 ? 53.066 46.043 13.147 1.00 10.53 ? 474 LYS B O 1 ATOM 8541 C CB . LYS B 1 474 ? 56.098 47.563 12.804 1.00 12.85 ? 474 LYS B CB 1 ATOM 8542 C CG . LYS B 1 474 ? 56.672 48.964 12.831 1.00 15.10 ? 474 LYS B CG 1 ATOM 8543 C CD . LYS B 1 474 ? 57.975 49.000 13.599 1.00 18.82 ? 474 LYS B CD 1 ATOM 8544 C CE . LYS B 1 474 ? 58.993 49.896 12.904 1.00 21.48 ? 474 LYS B CE 1 ATOM 8545 N NZ . LYS B 1 474 ? 59.498 49.304 11.620 1.00 24.85 ? 474 LYS B NZ 1 ATOM 8546 N N . ILE B 1 475 ? 54.992 44.885 13.290 1.00 9.76 ? 475 ILE B N 1 ATOM 8547 C CA . ILE B 1 475 ? 54.375 43.656 12.817 1.00 8.75 ? 475 ILE B CA 1 ATOM 8548 C C . ILE B 1 475 ? 53.128 43.214 13.582 1.00 8.60 ? 475 ILE B C 1 ATOM 8549 O O . ILE B 1 475 ? 52.292 42.487 13.031 1.00 8.45 ? 475 ILE B O 1 ATOM 8550 C CB . ILE B 1 475 ? 55.417 42.519 12.724 1.00 7.72 ? 475 ILE B CB 1 ATOM 8551 C CG1 . ILE B 1 475 ? 54.906 41.268 13.428 1.00 7.57 ? 475 ILE B CG1 1 ATOM 8552 C CG2 . ILE B 1 475 ? 56.752 43.007 13.257 1.00 7.29 ? 475 ILE B CG2 1 ATOM 8553 C CD1 . ILE B 1 475 ? 55.625 40.015 12.993 1.00 9.21 ? 475 ILE B CD1 1 ATOM 8554 N N . LEU B 1 476 ? 52.986 43.635 14.838 1.00 7.04 ? 476 LEU B N 1 ATOM 8555 C CA . LEU B 1 476 ? 51.767 43.283 15.556 1.00 5.58 ? 476 LEU B CA 1 ATOM 8556 C C . LEU B 1 476 ? 50.748 44.289 15.059 1.00 5.64 ? 476 LEU B C 1 ATOM 8557 O O . LEU B 1 476 ? 49.640 43.933 14.665 1.00 6.53 ? 476 LEU B O 1 ATOM 8558 C CB . LEU B 1 476 ? 51.906 43.424 17.072 1.00 4.00 ? 476 LEU B CB 1 ATOM 8559 C CG . LEU B 1 476 ? 50.538 43.341 17.778 1.00 3.10 ? 476 LEU B CG 1 ATOM 8560 C CD1 . LEU B 1 476 ? 49.821 42.062 17.373 1.00 2.00 ? 476 LEU B CD1 1 ATOM 8561 C CD2 . LEU B 1 476 ? 50.706 43.405 19.294 1.00 2.41 ? 476 LEU B CD2 1 ATOM 8562 N N . ALA B 1 477 ? 51.144 45.554 15.061 1.00 4.74 ? 477 ALA B N 1 ATOM 8563 C CA . ALA B 1 477 ? 50.260 46.613 14.605 1.00 5.81 ? 477 ALA B CA 1 ATOM 8564 C C . ALA B 1 477 ? 49.756 46.319 13.194 1.00 6.28 ? 477 ALA B C 1 ATOM 8565 O O . ALA B 1 477 ? 48.632 46.694 12.827 1.00 3.03 ? 477 ALA B O 1 ATOM 8566 C CB . ALA B 1 477 ? 50.990 47.951 14.639 1.00 5.25 ? 477 ALA B CB 1 ATOM 8567 N N . LYS B 1 478 ? 50.582 45.632 12.407 1.00 7.89 ? 478 LYS B N 1 ATOM 8568 C CA . LYS B 1 478 ? 50.203 45.312 11.037 1.00 10.32 ? 478 LYS B CA 1 ATOM 8569 C C . LYS B 1 478 ? 49.309 44.081 10.949 1.00 8.76 ? 478 LYS B C 1 ATOM 8570 O O . LYS B 1 478 ? 48.172 44.177 10.489 1.00 8.32 ? 478 LYS B O 1 ATOM 8571 C CB . LYS B 1 478 ? 51.445 45.131 10.154 1.00 13.12 ? 478 LYS B CB 1 ATOM 8572 C CG . LYS B 1 478 ? 51.109 45.009 8.660 1.00 17.49 ? 478 LYS B CG 1 ATOM 8573 C CD . LYS B 1 478 ? 52.353 45.063 7.766 1.00 20.87 ? 478 LYS B CD 1 ATOM 8574 C CE . LYS B 1 478 ? 53.041 46.428 7.838 1.00 22.31 ? 478 LYS B CE 1 ATOM 8575 N NZ . LYS B 1 478 ? 54.198 46.554 6.901 1.00 24.38 ? 478 LYS B NZ 1 ATOM 8576 N N . LYS B 1 479 ? 49.806 42.929 11.390 1.00 7.58 ? 479 LYS B N 1 ATOM 8577 C CA . LYS B 1 479 ? 48.999 41.712 11.329 1.00 7.71 ? 479 LYS B CA 1 ATOM 8578 C C . LYS B 1 479 ? 47.585 42.021 11.811 1.00 7.40 ? 479 LYS B C 1 ATOM 8579 O O . LYS B 1 479 ? 46.594 41.568 11.233 1.00 6.86 ? 479 LYS B O 1 ATOM 8580 C CB . LYS B 1 479 ? 49.590 40.607 12.217 1.00 8.04 ? 479 LYS B CB 1 ATOM 8581 C CG . LYS B 1 479 ? 50.917 40.010 11.756 1.00 9.77 ? 479 LYS B CG 1 ATOM 8582 C CD . LYS B 1 479 ? 51.116 38.631 12.401 1.00 11.90 ? 479 LYS B CD 1 ATOM 8583 C CE . LYS B 1 479 ? 52.537 38.088 12.249 1.00 12.22 ? 479 LYS B CE 1 ATOM 8584 N NZ . LYS B 1 479 ? 53.298 38.130 13.542 1.00 12.89 ? 479 LYS B NZ 1 ATOM 8585 N N . LEU B 1 480 ? 47.516 42.820 12.869 1.00 6.59 ? 480 LEU B N 1 ATOM 8586 C CA . LEU B 1 480 ? 46.261 43.201 13.486 1.00 5.65 ? 480 LEU B CA 1 ATOM 8587 C C . LEU B 1 480 ? 45.246 43.742 12.500 1.00 6.69 ? 480 LEU B C 1 ATOM 8588 O O . LEU B 1 480 ? 44.202 43.126 12.280 1.00 7.26 ? 480 LEU B O 1 ATOM 8589 C CB . LEU B 1 480 ? 46.525 44.224 14.591 1.00 5.08 ? 480 LEU B CB 1 ATOM 8590 C CG . LEU B 1 480 ? 45.743 44.054 15.900 1.00 3.90 ? 480 LEU B CG 1 ATOM 8591 C CD1 . LEU B 1 480 ? 45.560 42.588 16.217 1.00 3.35 ? 480 LEU B CD1 1 ATOM 8592 C CD2 . LEU B 1 480 ? 46.489 44.736 17.032 1.00 3.89 ? 480 LEU B CD2 1 ATOM 8593 N N . LEU B 1 481 ? 45.535 44.880 11.884 1.00 7.81 ? 481 LEU B N 1 ATOM 8594 C CA . LEU B 1 481 ? 44.552 45.418 10.956 1.00 9.75 ? 481 LEU B CA 1 ATOM 8595 C C . LEU B 1 481 ? 44.566 44.919 9.503 1.00 9.34 ? 481 LEU B C 1 ATOM 8596 O O . LEU B 1 481 ? 43.838 45.441 8.662 1.00 8.82 ? 481 LEU B O 1 ATOM 8597 C CB . LEU B 1 481 ? 44.559 46.944 11.014 1.00 8.72 ? 481 LEU B CB 1 ATOM 8598 C CG . LEU B 1 481 ? 45.952 47.535 11.059 1.00 9.99 ? 481 LEU B CG 1 ATOM 8599 C CD1 . LEU B 1 481 ? 46.647 47.195 9.752 1.00 12.28 ? 481 LEU B CD1 1 ATOM 8600 C CD2 . LEU B 1 481 ? 45.876 49.036 11.268 1.00 11.45 ? 481 LEU B CD2 1 ATOM 8601 N N . ASP B 1 482 ? 45.413 43.955 9.151 1.00 8.73 ? 482 ASP B N 1 ATOM 8602 C CA . ASP B 1 482 ? 45.321 43.360 7.831 1.00 9.30 ? 482 ASP B CA 1 ATOM 8603 C C . ASP B 1 482 ? 43.991 42.600 8.009 1.00 9.19 ? 482 ASP B C 1 ATOM 8604 O O . ASP B 1 482 ? 43.421 42.074 7.058 1.00 9.93 ? 482 ASP B O 1 ATOM 8605 C CB . ASP B 1 482 ? 46.445 42.302 7.514 1.00 12.32 ? 482 ASP B CB 1 ATOM 8606 C CG . ASP B 1 482 ? 47.889 42.743 7.130 1.00 15.86 ? 482 ASP B CG 1 ATOM 8607 O OD1 . ASP B 1 482 ? 48.219 43.938 7.311 1.00 16.53 ? 482 ASP B OD1 1 ATOM 8608 O OD2 . ASP B 1 482 ? 48.670 41.889 6.663 1.00 16.07 ? 482 ASP B OD2 1 ATOM 8609 N N . LEU B 1 483 ? 43.534 42.553 9.261 1.00 7.33 ? 483 LEU B N 1 ATOM 8610 C CA . LEU B 1 483 ? 42.339 41.825 9.674 1.00 4.53 ? 483 LEU B CA 1 ATOM 8611 C C . LEU B 1 483 ? 41.131 42.672 10.012 1.00 4.12 ? 483 LEU B C 1 ATOM 8612 O O . LEU B 1 483 ? 40.028 42.417 9.536 1.00 4.43 ? 483 LEU B O 1 ATOM 8613 C CB . LEU B 1 483 ? 42.663 40.986 10.898 1.00 4.52 ? 483 LEU B CB 1 ATOM 8614 C CG . LEU B 1 483 ? 43.443 39.708 10.651 1.00 4.77 ? 483 LEU B CG 1 ATOM 8615 C CD1 . LEU B 1 483 ? 44.263 39.347 11.874 1.00 4.27 ? 483 LEU B CD1 1 ATOM 8616 C CD2 . LEU B 1 483 ? 42.458 38.611 10.303 1.00 6.24 ? 483 LEU B CD2 1 ATOM 8617 N N . TYR B 1 484 ? 41.328 43.661 10.872 1.00 3.12 ? 484 TYR B N 1 ATOM 8618 C CA . TYR B 1 484 ? 40.221 44.507 11.279 1.00 2.17 ? 484 TYR B CA 1 ATOM 8619 C C . TYR B 1 484 ? 39.997 45.651 10.324 1.00 2.00 ? 484 TYR B C 1 ATOM 8620 O O . TYR B 1 484 ? 38.889 46.150 10.204 1.00 2.00 ? 484 TYR B O 1 ATOM 8621 C CB . TYR B 1 484 ? 40.452 45.003 12.707 1.00 2.59 ? 484 TYR B CB 1 ATOM 8622 C CG . TYR B 1 484 ? 40.178 43.912 13.723 1.00 2.96 ? 484 TYR B CG 1 ATOM 8623 C CD1 . TYR B 1 484 ? 38.871 43.530 14.019 1.00 2.00 ? 484 TYR B CD1 1 ATOM 8624 C CD2 . TYR B 1 484 ? 41.220 43.218 14.332 1.00 2.00 ? 484 TYR B CD2 1 ATOM 8625 C CE1 . TYR B 1 484 ? 38.611 42.497 14.883 1.00 2.00 ? 484 TYR B CE1 1 ATOM 8626 C CE2 . TYR B 1 484 ? 40.968 42.180 15.198 1.00 2.00 ? 484 TYR B CE2 1 ATOM 8627 C CZ . TYR B 1 484 ? 39.660 41.824 15.470 1.00 2.00 ? 484 TYR B CZ 1 ATOM 8628 O OH . TYR B 1 484 ? 39.405 40.789 16.341 1.00 4.35 ? 484 TYR B OH 1 ATOM 8629 N N . LYS B 1 485 ? 41.060 46.032 9.628 1.00 3.83 ? 485 LYS B N 1 ATOM 8630 C CA . LYS B 1 485 ? 41.049 47.111 8.642 1.00 3.43 ? 485 LYS B CA 1 ATOM 8631 C C . LYS B 1 485 ? 41.070 48.523 9.217 1.00 3.13 ? 485 LYS B C 1 ATOM 8632 O O . LYS B 1 485 ? 41.404 49.475 8.511 1.00 3.37 ? 485 LYS B O 1 ATOM 8633 C CB . LYS B 1 485 ? 39.879 46.936 7.674 1.00 4.55 ? 485 LYS B CB 1 ATOM 8634 C CG . LYS B 1 485 ? 40.063 45.751 6.730 1.00 7.99 ? 485 LYS B CG 1 ATOM 8635 C CD . LYS B 1 485 ? 41.419 45.830 6.014 1.00 11.62 ? 485 LYS B CD 1 ATOM 8636 C CE . LYS B 1 485 ? 41.599 44.734 4.952 1.00 13.82 ? 485 LYS B CE 1 ATOM 8637 N NZ . LYS B 1 485 ? 41.506 43.346 5.502 1.00 14.15 ? 485 LYS B NZ 1 ATOM 8638 N N . THR B 1 486 ? 40.727 48.657 10.497 1.00 4.39 ? 486 THR B N 1 ATOM 8639 C CA . THR B 1 486 ? 40.753 49.955 11.173 1.00 2.79 ? 486 THR B CA 1 ATOM 8640 C C . THR B 1 486 ? 40.745 49.843 12.690 1.00 2.89 ? 486 THR B C 1 ATOM 8641 O O . THR B 1 486 ? 40.042 49.013 13.265 1.00 4.00 ? 486 THR B O 1 ATOM 8642 C CB . THR B 1 486 ? 39.568 50.844 10.799 1.00 3.02 ? 486 THR B CB 1 ATOM 8643 O OG1 . THR B 1 486 ? 39.722 52.109 11.455 1.00 4.28 ? 486 THR B OG1 1 ATOM 8644 C CG2 . THR B 1 486 ? 38.253 50.218 11.250 1.00 2.00 ? 486 THR B CG2 1 ATOM 8645 N N . PRO B 1 487 ? 41.528 50.692 13.362 1.00 2.55 ? 487 PRO B N 1 ATOM 8646 C CA . PRO B 1 487 ? 41.601 50.682 14.825 1.00 4.75 ? 487 PRO B CA 1 ATOM 8647 C C . PRO B 1 487 ? 40.223 50.682 15.500 1.00 3.32 ? 487 PRO B C 1 ATOM 8648 O O . PRO B 1 487 ? 40.059 50.123 16.590 1.00 2.05 ? 487 PRO B O 1 ATOM 8649 C CB . PRO B 1 487 ? 42.391 51.950 15.132 1.00 3.73 ? 487 PRO B CB 1 ATOM 8650 C CG . PRO B 1 487 ? 43.341 52.022 13.978 1.00 3.69 ? 487 PRO B CG 1 ATOM 8651 C CD . PRO B 1 487 ? 42.453 51.688 12.794 1.00 3.39 ? 487 PRO B CD 1 ATOM 8652 N N . ASP B 1 488 ? 39.235 51.304 14.853 1.00 3.52 ? 488 ASP B N 1 ATOM 8653 C CA . ASP B 1 488 ? 37.885 51.372 15.421 1.00 4.05 ? 488 ASP B CA 1 ATOM 8654 C C . ASP B 1 488 ? 37.156 50.025 15.519 1.00 3.80 ? 488 ASP B C 1 ATOM 8655 O O . ASP B 1 488 ? 36.126 49.944 16.178 1.00 4.74 ? 488 ASP B O 1 ATOM 8656 C CB . ASP B 1 488 ? 36.976 52.333 14.624 1.00 2.00 ? 488 ASP B CB 1 ATOM 8657 C CG . ASP B 1 488 ? 37.459 53.784 14.638 1.00 2.00 ? 488 ASP B CG 1 ATOM 8658 O OD1 . ASP B 1 488 ? 37.882 54.294 15.696 1.00 2.00 ? 488 ASP B OD1 1 ATOM 8659 O OD2 . ASP B 1 488 ? 37.382 54.434 13.574 1.00 4.10 ? 488 ASP B OD2 1 ATOM 8660 N N . ASN B 1 489 ? 37.669 48.973 14.884 1.00 2.90 ? 489 ASN B N 1 ATOM 8661 C CA . ASN B 1 489 ? 36.970 47.686 14.918 1.00 2.31 ? 489 ASN B CA 1 ATOM 8662 C C . ASN B 1 489 ? 37.543 46.549 15.750 1.00 5.77 ? 489 ASN B C 1 ATOM 8663 O O . ASN B 1 489 ? 36.856 45.549 15.993 1.00 5.41 ? 489 ASN B O 1 ATOM 8664 C CB . ASN B 1 489 ? 36.757 47.195 13.497 1.00 2.00 ? 489 ASN B CB 1 ATOM 8665 C CG . ASN B 1 489 ? 35.557 47.817 12.869 1.00 2.00 ? 489 ASN B CG 1 ATOM 8666 O OD1 . ASN B 1 489 ? 35.149 48.905 13.260 1.00 2.00 ? 489 ASN B OD1 1 ATOM 8667 N ND2 . ASN B 1 489 ? 34.976 47.140 11.888 1.00 2.00 ? 489 ASN B ND2 1 ATOM 8668 N N . ILE B 1 490 ? 38.794 46.701 16.175 1.00 5.03 ? 490 ILE B N 1 ATOM 8669 C CA . ILE B 1 490 ? 39.483 45.699 16.980 1.00 2.00 ? 490 ILE B CA 1 ATOM 8670 C C . ILE B 1 490 ? 38.703 45.321 18.231 1.00 2.00 ? 490 ILE B C 1 ATOM 8671 O O . ILE B 1 490 ? 38.279 46.195 18.982 1.00 2.00 ? 490 ILE B O 1 ATOM 8672 C CB . ILE B 1 490 ? 40.846 46.229 17.452 1.00 2.00 ? 490 ILE B CB 1 ATOM 8673 C CG1 . ILE B 1 490 ? 41.729 46.556 16.250 1.00 2.20 ? 490 ILE B CG1 1 ATOM 8674 C CG2 . ILE B 1 490 ? 41.499 45.224 18.373 1.00 2.00 ? 490 ILE B CG2 1 ATOM 8675 C CD1 . ILE B 1 490 ? 43.139 46.988 16.639 1.00 2.00 ? 490 ILE B CD1 1 ATOM 8676 N N . ASP B 1 491 ? 38.530 44.023 18.462 1.00 2.00 ? 491 ASP B N 1 ATOM 8677 C CA . ASP B 1 491 ? 37.836 43.539 19.659 1.00 2.79 ? 491 ASP B CA 1 ATOM 8678 C C . ASP B 1 491 ? 38.578 43.945 20.940 1.00 3.20 ? 491 ASP B C 1 ATOM 8679 O O . ASP B 1 491 ? 39.803 43.796 21.056 1.00 3.67 ? 491 ASP B O 1 ATOM 8680 C CB . ASP B 1 491 ? 37.704 42.019 19.622 1.00 2.11 ? 491 ASP B CB 1 ATOM 8681 C CG . ASP B 1 491 ? 36.795 41.550 18.522 1.00 2.57 ? 491 ASP B CG 1 ATOM 8682 O OD1 . ASP B 1 491 ? 35.605 41.923 18.541 1.00 3.02 ? 491 ASP B OD1 1 ATOM 8683 O OD2 . ASP B 1 491 ? 37.264 40.809 17.637 1.00 4.40 ? 491 ASP B OD2 1 ATOM 8684 N N . ILE B 1 492 ? 37.826 44.432 21.915 1.00 2.00 ? 492 ILE B N 1 ATOM 8685 C CA . ILE B 1 492 ? 38.418 44.882 23.158 1.00 2.03 ? 492 ILE B CA 1 ATOM 8686 C C . ILE B 1 492 ? 39.374 43.883 23.821 1.00 3.39 ? 492 ILE B C 1 ATOM 8687 O O . ILE B 1 492 ? 40.489 44.249 24.205 1.00 4.21 ? 492 ILE B O 1 ATOM 8688 C CB . ILE B 1 492 ? 37.305 45.311 24.141 1.00 2.00 ? 492 ILE B CB 1 ATOM 8689 C CG1 . ILE B 1 492 ? 37.916 45.799 25.459 1.00 2.11 ? 492 ILE B CG1 1 ATOM 8690 C CG2 . ILE B 1 492 ? 36.322 44.182 24.314 1.00 2.00 ? 492 ILE B CG2 1 ATOM 8691 C CD1 . ILE B 1 492 ? 38.824 47.019 25.315 1.00 2.00 ? 492 ILE B CD1 1 ATOM 8692 N N . TRP B 1 493 ? 38.965 42.627 23.952 1.00 2.00 ? 493 TRP B N 1 ATOM 8693 C CA . TRP B 1 493 ? 39.834 41.646 24.588 1.00 2.00 ? 493 TRP B CA 1 ATOM 8694 C C . TRP B 1 493 ? 41.222 41.630 23.980 1.00 2.00 ? 493 TRP B C 1 ATOM 8695 O O . TRP B 1 493 ? 42.223 41.760 24.671 1.00 4.12 ? 493 TRP B O 1 ATOM 8696 C CB . TRP B 1 493 ? 39.250 40.253 24.467 1.00 2.00 ? 493 TRP B CB 1 ATOM 8697 C CG . TRP B 1 493 ? 40.071 39.249 25.149 1.00 2.00 ? 493 TRP B CG 1 ATOM 8698 C CD1 . TRP B 1 493 ? 40.205 39.085 26.486 1.00 2.00 ? 493 TRP B CD1 1 ATOM 8699 C CD2 . TRP B 1 493 ? 40.871 38.240 24.533 1.00 2.21 ? 493 TRP B CD2 1 ATOM 8700 N NE1 . TRP B 1 493 ? 41.036 38.031 26.750 1.00 2.00 ? 493 TRP B NE1 1 ATOM 8701 C CE2 . TRP B 1 493 ? 41.461 37.492 25.565 1.00 2.00 ? 493 TRP B CE2 1 ATOM 8702 C CE3 . TRP B 1 493 ? 41.145 37.890 23.203 1.00 3.58 ? 493 TRP B CE3 1 ATOM 8703 C CZ2 . TRP B 1 493 ? 42.312 36.410 25.316 1.00 2.00 ? 493 TRP B CZ2 1 ATOM 8704 C CZ3 . TRP B 1 493 ? 41.994 36.809 22.954 1.00 2.00 ? 493 TRP B CZ3 1 ATOM 8705 C CH2 . TRP B 1 493 ? 42.564 36.085 24.007 1.00 2.00 ? 493 TRP B CH2 1 ATOM 8706 N N . ILE B 1 494 ? 41.274 41.474 22.670 1.00 2.00 ? 494 ILE B N 1 ATOM 8707 C CA . ILE B 1 494 ? 42.540 41.421 21.982 1.00 2.00 ? 494 ILE B CA 1 ATOM 8708 C C . ILE B 1 494 ? 43.201 42.799 21.933 1.00 2.34 ? 494 ILE B C 1 ATOM 8709 O O . ILE B 1 494 ? 44.367 42.941 22.304 1.00 2.00 ? 494 ILE B O 1 ATOM 8710 C CB . ILE B 1 494 ? 42.331 40.854 20.566 1.00 2.04 ? 494 ILE B CB 1 ATOM 8711 C CG1 . ILE B 1 494 ? 43.561 40.053 20.145 1.00 2.02 ? 494 ILE B CG1 1 ATOM 8712 C CG2 . ILE B 1 494 ? 42.020 41.976 19.577 1.00 2.00 ? 494 ILE B CG2 1 ATOM 8713 C CD1 . ILE B 1 494 ? 44.762 40.897 19.856 1.00 3.12 ? 494 ILE B CD1 1 ATOM 8714 N N . GLY B 1 495 ? 42.443 43.809 21.505 1.00 2.40 ? 495 GLY B N 1 ATOM 8715 C CA . GLY B 1 495 ? 42.971 45.159 21.400 1.00 2.00 ? 495 GLY B CA 1 ATOM 8716 C C . GLY B 1 495 ? 43.559 45.676 22.692 1.00 2.00 ? 495 GLY B C 1 ATOM 8717 O O . GLY B 1 495 ? 44.563 46.389 22.687 1.00 2.00 ? 495 GLY B O 1 ATOM 8718 N N . GLY B 1 496 ? 42.930 45.308 23.804 1.00 2.35 ? 496 GLY B N 1 ATOM 8719 C CA . GLY B 1 496 ? 43.395 45.744 25.106 1.00 2.00 ? 496 GLY B CA 1 ATOM 8720 C C . GLY B 1 496 ? 44.694 45.082 25.517 1.00 2.00 ? 496 GLY B C 1 ATOM 8721 O O . GLY B 1 496 ? 45.621 45.758 25.976 1.00 2.19 ? 496 GLY B O 1 ATOM 8722 N N . ASN B 1 497 ? 44.759 43.762 25.349 1.00 2.00 ? 497 ASN B N 1 ATOM 8723 C CA . ASN B 1 497 ? 45.943 42.984 25.706 1.00 2.00 ? 497 ASN B CA 1 ATOM 8724 C C . ASN B 1 497 ? 47.135 43.261 24.814 1.00 2.00 ? 497 ASN B C 1 ATOM 8725 O O . ASN B 1 497 ? 48.286 43.068 25.203 1.00 2.00 ? 497 ASN B O 1 ATOM 8726 C CB . ASN B 1 497 ? 45.659 41.506 25.638 1.00 2.34 ? 497 ASN B CB 1 ATOM 8727 C CG . ASN B 1 497 ? 44.794 41.043 26.775 1.00 2.68 ? 497 ASN B CG 1 ATOM 8728 O OD1 . ASN B 1 497 ? 45.262 40.319 27.642 1.00 7.08 ? 497 ASN B OD1 1 ATOM 8729 N ND2 . ASN B 1 497 ? 43.532 41.442 26.779 1.00 4.27 ? 497 ASN B ND2 1 ATOM 8730 N N . ALA B 1 498 ? 46.854 43.704 23.603 1.00 2.25 ? 498 ALA B N 1 ATOM 8731 C CA . ALA B 1 498 ? 47.911 44.001 22.661 1.00 2.02 ? 498 ALA B CA 1 ATOM 8732 C C . ALA B 1 498 ? 48.857 45.069 23.196 1.00 2.00 ? 498 ALA B C 1 ATOM 8733 O O . ALA B 1 498 ? 50.042 45.062 22.878 1.00 2.00 ? 498 ALA B O 1 ATOM 8734 C CB . ALA B 1 498 ? 47.306 44.445 21.320 1.00 2.56 ? 498 ALA B CB 1 ATOM 8735 N N . GLU B 1 499 ? 48.346 45.979 24.017 1.00 2.00 ? 499 GLU B N 1 ATOM 8736 C CA . GLU B 1 499 ? 49.184 47.054 24.545 1.00 2.75 ? 499 GLU B CA 1 ATOM 8737 C C . GLU B 1 499 ? 50.298 46.567 25.471 1.00 2.27 ? 499 GLU B C 1 ATOM 8738 O O . GLU B 1 499 ? 50.129 45.587 26.198 1.00 2.00 ? 499 GLU B O 1 ATOM 8739 C CB . GLU B 1 499 ? 48.329 48.079 25.297 1.00 2.27 ? 499 GLU B CB 1 ATOM 8740 C CG . GLU B 1 499 ? 46.982 48.366 24.651 1.00 2.51 ? 499 GLU B CG 1 ATOM 8741 C CD . GLU B 1 499 ? 46.283 49.573 25.262 1.00 3.43 ? 499 GLU B CD 1 ATOM 8742 O OE1 . GLU B 1 499 ? 46.324 49.725 26.507 1.00 4.31 ? 499 GLU B OE1 1 ATOM 8743 O OE2 . GLU B 1 499 ? 45.683 50.363 24.498 1.00 2.21 ? 499 GLU B OE2 1 ATOM 8744 N N . PRO B 1 500 ? 51.466 47.235 25.435 1.00 2.00 ? 500 PRO B N 1 ATOM 8745 C CA . PRO B 1 500 ? 52.571 46.832 26.305 1.00 2.16 ? 500 PRO B CA 1 ATOM 8746 C C . PRO B 1 500 ? 52.173 47.168 27.743 1.00 3.54 ? 500 PRO B C 1 ATOM 8747 O O . PRO B 1 500 ? 51.342 48.052 27.975 1.00 3.20 ? 500 PRO B O 1 ATOM 8748 C CB . PRO B 1 500 ? 53.732 47.674 25.797 1.00 2.00 ? 500 PRO B CB 1 ATOM 8749 C CG . PRO B 1 500 ? 53.053 48.915 25.332 1.00 2.00 ? 500 PRO B CG 1 ATOM 8750 C CD . PRO B 1 500 ? 51.863 48.370 24.587 1.00 2.00 ? 500 PRO B CD 1 ATOM 8751 N N . MET B 1 501 ? 52.766 46.468 28.702 1.00 2.45 ? 501 MET B N 1 ATOM 8752 C CA . MET B 1 501 ? 52.434 46.664 30.105 1.00 2.00 ? 501 MET B CA 1 ATOM 8753 C C . MET B 1 501 ? 53.028 47.898 30.757 1.00 2.00 ? 501 MET B C 1 ATOM 8754 O O . MET B 1 501 ? 54.194 48.235 30.545 1.00 2.13 ? 501 MET B O 1 ATOM 8755 C CB . MET B 1 501 ? 52.866 45.442 30.900 1.00 2.81 ? 501 MET B CB 1 ATOM 8756 C CG . MET B 1 501 ? 52.312 44.134 30.388 1.00 2.00 ? 501 MET B CG 1 ATOM 8757 S SD . MET B 1 501 ? 53.333 42.828 31.064 1.00 6.82 ? 501 MET B SD 1 ATOM 8758 C CE . MET B 1 501 ? 52.552 41.320 30.462 1.00 2.11 ? 501 MET B CE 1 ATOM 8759 N N . VAL B 1 502 ? 52.220 48.555 31.578 1.00 2.00 ? 502 VAL B N 1 ATOM 8760 C CA . VAL B 1 502 ? 52.656 49.741 32.301 1.00 3.20 ? 502 VAL B CA 1 ATOM 8761 C C . VAL B 1 502 ? 53.789 49.370 33.236 1.00 4.38 ? 502 VAL B C 1 ATOM 8762 O O . VAL B 1 502 ? 54.001 48.196 33.532 1.00 5.00 ? 502 VAL B O 1 ATOM 8763 C CB . VAL B 1 502 ? 51.562 50.274 33.174 1.00 2.00 ? 502 VAL B CB 1 ATOM 8764 C CG1 . VAL B 1 502 ? 50.306 50.471 32.360 1.00 3.23 ? 502 VAL B CG1 1 ATOM 8765 C CG2 . VAL B 1 502 ? 51.332 49.303 34.316 1.00 2.22 ? 502 VAL B CG2 1 ATOM 8766 N N . GLU B 1 503 ? 54.479 50.388 33.737 1.00 7.22 ? 503 GLU B N 1 ATOM 8767 C CA . GLU B 1 503 ? 55.608 50.209 34.646 1.00 8.41 ? 503 GLU B CA 1 ATOM 8768 C C . GLU B 1 503 ? 55.273 49.456 35.941 1.00 7.50 ? 503 GLU B C 1 ATOM 8769 O O . GLU B 1 503 ? 54.409 49.870 36.713 1.00 7.11 ? 503 GLU B O 1 ATOM 8770 C CB . GLU B 1 503 ? 56.214 51.575 34.975 1.00 10.76 ? 503 GLU B CB 1 ATOM 8771 C CG . GLU B 1 503 ? 57.330 51.519 35.983 1.00 16.89 ? 503 GLU B CG 1 ATOM 8772 C CD . GLU B 1 503 ? 58.012 52.861 36.171 1.00 20.12 ? 503 GLU B CD 1 ATOM 8773 O OE1 . GLU B 1 503 ? 58.701 53.302 35.223 1.00 21.68 ? 503 GLU B OE1 1 ATOM 8774 O OE2 . GLU B 1 503 ? 57.858 53.471 37.261 1.00 21.29 ? 503 GLU B OE2 1 ATOM 8775 N N . ARG B 1 504 ? 55.981 48.349 36.156 1.00 7.40 ? 504 ARG B N 1 ATOM 8776 C CA . ARG B 1 504 ? 55.820 47.480 37.323 1.00 6.96 ? 504 ARG B CA 1 ATOM 8777 C C . ARG B 1 504 ? 54.442 46.837 37.483 1.00 5.38 ? 504 ARG B C 1 ATOM 8778 O O . ARG B 1 504 ? 54.047 46.494 38.596 1.00 4.20 ? 504 ARG B O 1 ATOM 8779 C CB . ARG B 1 504 ? 56.193 48.230 38.603 1.00 9.63 ? 504 ARG B CB 1 ATOM 8780 C CG . ARG B 1 504 ? 57.561 48.899 38.537 1.00 16.70 ? 504 ARG B CG 1 ATOM 8781 C CD . ARG B 1 504 ? 58.138 49.178 39.928 1.00 21.47 ? 504 ARG B CD 1 ATOM 8782 N NE . ARG B 1 504 ? 58.885 48.039 40.463 1.00 26.39 ? 504 ARG B NE 1 ATOM 8783 C CZ . ARG B 1 504 ? 60.011 47.567 39.930 1.00 28.28 ? 504 ARG B CZ 1 ATOM 8784 N NH1 . ARG B 1 504 ? 60.527 48.131 38.841 1.00 30.14 ? 504 ARG B NH1 1 ATOM 8785 N NH2 . ARG B 1 504 ? 60.627 46.534 40.490 1.00 30.13 ? 504 ARG B NH2 1 ATOM 8786 N N . GLY B 1 505 ? 53.726 46.662 36.371 1.00 4.44 ? 505 GLY B N 1 ATOM 8787 C CA . GLY B 1 505 ? 52.403 46.044 36.397 1.00 3.78 ? 505 GLY B CA 1 ATOM 8788 C C . GLY B 1 505 ? 52.304 44.838 35.463 1.00 3.99 ? 505 GLY B C 1 ATOM 8789 O O . GLY B 1 505 ? 53.331 44.279 35.079 1.00 4.40 ? 505 GLY B O 1 ATOM 8790 N N . ARG B 1 506 ? 51.094 44.419 35.093 1.00 2.17 ? 506 ARG B N 1 ATOM 8791 C CA . ARG B 1 506 ? 50.958 43.271 34.196 1.00 2.00 ? 506 ARG B CA 1 ATOM 8792 C C . ARG B 1 506 ? 49.883 43.461 33.148 1.00 2.13 ? 506 ARG B C 1 ATOM 8793 O O . ARG B 1 506 ? 49.450 42.506 32.495 1.00 2.00 ? 506 ARG B O 1 ATOM 8794 C CB . ARG B 1 506 ? 50.687 41.989 34.976 1.00 2.00 ? 506 ARG B CB 1 ATOM 8795 C CG . ARG B 1 506 ? 51.801 41.576 35.908 1.00 2.92 ? 506 ARG B CG 1 ATOM 8796 C CD . ARG B 1 506 ? 53.140 41.596 35.172 1.00 3.61 ? 506 ARG B CD 1 ATOM 8797 N NE . ARG B 1 506 ? 54.233 41.193 36.028 1.00 5.80 ? 506 ARG B NE 1 ATOM 8798 C CZ . ARG B 1 506 ? 55.519 41.350 35.727 1.00 8.09 ? 506 ARG B CZ 1 ATOM 8799 N NH1 . ARG B 1 506 ? 55.865 41.896 34.565 1.00 7.75 ? 506 ARG B NH1 1 ATOM 8800 N NH2 . ARG B 1 506 ? 56.460 40.966 36.587 1.00 8.36 ? 506 ARG B NH2 1 ATOM 8801 N N . VAL B 1 507 ? 49.449 44.708 33.011 1.00 2.64 ? 507 VAL B N 1 ATOM 8802 C CA . VAL B 1 507 ? 48.458 45.096 32.019 1.00 2.00 ? 507 VAL B CA 1 ATOM 8803 C C . VAL B 1 507 ? 48.808 46.526 31.634 1.00 3.27 ? 507 VAL B C 1 ATOM 8804 O O . VAL B 1 507 ? 49.422 47.252 32.421 1.00 3.04 ? 507 VAL B O 1 ATOM 8805 C CB . VAL B 1 507 ? 47.032 45.072 32.578 1.00 2.00 ? 507 VAL B CB 1 ATOM 8806 C CG1 . VAL B 1 507 ? 46.743 43.726 33.208 1.00 2.05 ? 507 VAL B CG1 1 ATOM 8807 C CG2 . VAL B 1 507 ? 46.854 46.191 33.573 1.00 2.03 ? 507 VAL B CG2 1 ATOM 8808 N N . GLY B 1 508 ? 48.411 46.930 30.431 1.00 2.98 ? 508 GLY B N 1 ATOM 8809 C CA . GLY B 1 508 ? 48.718 48.268 29.957 1.00 2.85 ? 508 GLY B CA 1 ATOM 8810 C C . GLY B 1 508 ? 47.772 49.384 30.366 1.00 2.00 ? 508 GLY B C 1 ATOM 8811 O O . GLY B 1 508 ? 46.951 49.217 31.265 1.00 2.00 ? 508 GLY B O 1 ATOM 8812 N N . PRO B 1 509 ? 47.887 50.552 29.715 1.00 2.00 ? 509 PRO B N 1 ATOM 8813 C CA . PRO B 1 509 ? 47.084 51.752 29.946 1.00 2.00 ? 509 PRO B CA 1 ATOM 8814 C C . PRO B 1 509 ? 45.583 51.529 29.995 1.00 2.96 ? 509 PRO B C 1 ATOM 8815 O O . PRO B 1 509 ? 44.920 51.944 30.945 1.00 2.77 ? 509 PRO B O 1 ATOM 8816 C CB . PRO B 1 509 ? 47.466 52.646 28.776 1.00 2.00 ? 509 PRO B CB 1 ATOM 8817 C CG . PRO B 1 509 ? 48.879 52.332 28.575 1.00 2.34 ? 509 PRO B CG 1 ATOM 8818 C CD . PRO B 1 509 ? 48.917 50.822 28.696 1.00 2.79 ? 509 PRO B CD 1 ATOM 8819 N N . LEU B 1 510 ? 45.035 50.888 28.971 1.00 2.01 ? 510 LEU B N 1 ATOM 8820 C CA . LEU B 1 510 ? 43.603 50.692 28.955 1.00 2.00 ? 510 LEU B CA 1 ATOM 8821 C C . LEU B 1 510 ? 43.100 49.666 29.948 1.00 2.20 ? 510 LEU B C 1 ATOM 8822 O O . LEU B 1 510 ? 42.056 49.876 30.559 1.00 3.15 ? 510 LEU B O 1 ATOM 8823 C CB . LEU B 1 510 ? 43.106 50.336 27.560 1.00 2.00 ? 510 LEU B CB 1 ATOM 8824 C CG . LEU B 1 510 ? 41.577 50.245 27.553 1.00 2.00 ? 510 LEU B CG 1 ATOM 8825 C CD1 . LEU B 1 510 ? 40.989 51.544 28.074 1.00 2.00 ? 510 LEU B CD1 1 ATOM 8826 C CD2 . LEU B 1 510 ? 41.078 49.943 26.158 1.00 2.00 ? 510 LEU B CD2 1 ATOM 8827 N N . LEU B 1 511 ? 43.805 48.554 30.118 1.00 2.00 ? 511 LEU B N 1 ATOM 8828 C CA . LEU B 1 511 ? 43.321 47.584 31.088 1.00 2.00 ? 511 LEU B CA 1 ATOM 8829 C C . LEU B 1 511 ? 43.437 48.131 32.501 1.00 2.00 ? 511 LEU B C 1 ATOM 8830 O O . LEU B 1 511 ? 42.593 47.853 33.342 1.00 2.58 ? 511 LEU B O 1 ATOM 8831 C CB . LEU B 1 511 ? 44.074 46.253 31.004 1.00 2.00 ? 511 LEU B CB 1 ATOM 8832 C CG . LEU B 1 511 ? 43.406 45.132 30.212 1.00 2.00 ? 511 LEU B CG 1 ATOM 8833 C CD1 . LEU B 1 511 ? 41.899 45.319 30.181 1.00 2.00 ? 511 LEU B CD1 1 ATOM 8834 C CD2 . LEU B 1 511 ? 43.952 45.142 28.819 1.00 2.00 ? 511 LEU B CD2 1 ATOM 8835 N N . ALA B 1 512 ? 44.476 48.910 32.767 1.00 2.00 ? 512 ALA B N 1 ATOM 8836 C CA . ALA B 1 512 ? 44.661 49.463 34.100 1.00 2.00 ? 512 ALA B CA 1 ATOM 8837 C C . ALA B 1 512 ? 43.487 50.365 34.462 1.00 3.84 ? 512 ALA B C 1 ATOM 8838 O O . ALA B 1 512 ? 43.043 50.404 35.614 1.00 4.01 ? 512 ALA B O 1 ATOM 8839 C CB . ALA B 1 512 ? 45.964 50.246 34.165 1.00 2.00 ? 512 ALA B CB 1 ATOM 8840 N N . CYS B 1 513 ? 42.989 51.086 33.463 1.00 2.00 ? 513 CYS B N 1 ATOM 8841 C CA . CYS B 1 513 ? 41.881 52.006 33.641 1.00 2.00 ? 513 CYS B CA 1 ATOM 8842 C C . CYS B 1 513 ? 40.598 51.260 33.941 1.00 2.00 ? 513 CYS B C 1 ATOM 8843 O O . CYS B 1 513 ? 39.949 51.511 34.949 1.00 2.00 ? 513 CYS B O 1 ATOM 8844 C CB . CYS B 1 513 ? 41.732 52.855 32.384 1.00 2.00 ? 513 CYS B CB 1 ATOM 8845 S SG . CYS B 1 513 ? 40.163 53.759 32.222 1.00 3.56 ? 513 CYS B SG 1 ATOM 8846 N N . LEU B 1 514 ? 40.242 50.327 33.072 1.00 2.00 ? 514 LEU B N 1 ATOM 8847 C CA . LEU B 1 514 ? 39.027 49.540 33.256 1.00 2.71 ? 514 LEU B CA 1 ATOM 8848 C C . LEU B 1 514 ? 38.982 48.698 34.531 1.00 2.45 ? 514 LEU B C 1 ATOM 8849 O O . LEU B 1 514 ? 37.904 48.466 35.065 1.00 3.38 ? 514 LEU B O 1 ATOM 8850 C CB . LEU B 1 514 ? 38.798 48.633 32.048 1.00 2.00 ? 514 LEU B CB 1 ATOM 8851 C CG . LEU B 1 514 ? 38.423 49.341 30.754 1.00 2.00 ? 514 LEU B CG 1 ATOM 8852 C CD1 . LEU B 1 514 ? 38.509 48.369 29.619 1.00 2.00 ? 514 LEU B CD1 1 ATOM 8853 C CD2 . LEU B 1 514 ? 37.021 49.909 30.869 1.00 2.20 ? 514 LEU B CD2 1 ATOM 8854 N N . LEU B 1 515 ? 40.129 48.223 35.011 1.00 2.00 ? 515 LEU B N 1 ATOM 8855 C CA . LEU B 1 515 ? 40.150 47.429 36.234 1.00 2.00 ? 515 LEU B CA 1 ATOM 8856 C C . LEU B 1 515 ? 40.152 48.377 37.417 1.00 2.20 ? 515 LEU B C 1 ATOM 8857 O O . LEU B 1 515 ? 39.342 48.248 38.340 1.00 2.29 ? 515 LEU B O 1 ATOM 8858 C CB . LEU B 1 515 ? 41.397 46.542 36.305 1.00 2.00 ? 515 LEU B CB 1 ATOM 8859 C CG . LEU B 1 515 ? 41.584 45.499 35.204 1.00 2.00 ? 515 LEU B CG 1 ATOM 8860 C CD1 . LEU B 1 515 ? 42.710 44.544 35.555 1.00 2.00 ? 515 LEU B CD1 1 ATOM 8861 C CD2 . LEU B 1 515 ? 40.299 44.735 35.035 1.00 2.64 ? 515 LEU B CD2 1 ATOM 8862 N N . GLY B 1 516 ? 41.072 49.335 37.376 1.00 2.16 ? 516 GLY B N 1 ATOM 8863 C CA . GLY B 1 516 ? 41.184 50.305 38.448 1.00 2.67 ? 516 GLY B CA 1 ATOM 8864 C C . GLY B 1 516 ? 39.831 50.819 38.887 1.00 2.18 ? 516 GLY B C 1 ATOM 8865 O O . GLY B 1 516 ? 39.452 50.694 40.054 1.00 2.00 ? 516 GLY B O 1 ATOM 8866 N N . ARG B 1 517 ? 39.099 51.388 37.938 1.00 2.65 ? 517 ARG B N 1 ATOM 8867 C CA . ARG B 1 517 ? 37.781 51.920 38.218 1.00 4.07 ? 517 ARG B CA 1 ATOM 8868 C C . ARG B 1 517 ? 36.867 50.882 38.851 1.00 5.33 ? 517 ARG B C 1 ATOM 8869 O O . ARG B 1 517 ? 36.350 51.084 39.959 1.00 5.98 ? 517 ARG B O 1 ATOM 8870 C CB . ARG B 1 517 ? 37.139 52.441 36.935 1.00 5.00 ? 517 ARG B CB 1 ATOM 8871 C CG . ARG B 1 517 ? 37.878 53.602 36.326 1.00 7.46 ? 517 ARG B CG 1 ATOM 8872 C CD . ARG B 1 517 ? 36.948 54.452 35.491 1.00 9.23 ? 517 ARG B CD 1 ATOM 8873 N NE . ARG B 1 517 ? 37.666 55.537 34.834 1.00 12.36 ? 517 ARG B NE 1 ATOM 8874 C CZ . ARG B 1 517 ? 37.077 56.529 34.181 1.00 13.59 ? 517 ARG B CZ 1 ATOM 8875 N NH1 . ARG B 1 517 ? 35.752 56.571 34.105 1.00 14.71 ? 517 ARG B NH1 1 ATOM 8876 N NH2 . ARG B 1 517 ? 37.813 57.471 33.596 1.00 14.99 ? 517 ARG B NH2 1 ATOM 8877 N N . GLN B 1 518 ? 36.666 49.774 38.145 1.00 3.24 ? 518 GLN B N 1 ATOM 8878 C CA . GLN B 1 518 ? 35.797 48.726 38.642 1.00 2.00 ? 518 GLN B CA 1 ATOM 8879 C C . GLN B 1 518 ? 36.087 48.422 40.097 1.00 2.94 ? 518 GLN B C 1 ATOM 8880 O O . GLN B 1 518 ? 35.207 48.537 40.952 1.00 2.37 ? 518 GLN B O 1 ATOM 8881 C CB . GLN B 1 518 ? 35.963 47.453 37.830 1.00 2.00 ? 518 GLN B CB 1 ATOM 8882 C CG . GLN B 1 518 ? 35.005 46.378 38.259 1.00 2.00 ? 518 GLN B CG 1 ATOM 8883 C CD . GLN B 1 518 ? 33.568 46.765 38.003 1.00 2.24 ? 518 GLN B CD 1 ATOM 8884 O OE1 . GLN B 1 518 ? 33.134 46.851 36.855 1.00 4.08 ? 518 GLN B OE1 1 ATOM 8885 N NE2 . GLN B 1 518 ? 32.821 47.009 39.071 1.00 2.00 ? 518 GLN B NE2 1 ATOM 8886 N N . PHE B 1 519 ? 37.331 48.050 40.383 1.00 3.22 ? 519 PHE B N 1 ATOM 8887 C CA . PHE B 1 519 ? 37.701 47.712 41.749 1.00 4.59 ? 519 PHE B CA 1 ATOM 8888 C C . PHE B 1 519 ? 37.437 48.793 42.781 1.00 5.76 ? 519 PHE B C 1 ATOM 8889 O O . PHE B 1 519 ? 36.893 48.502 43.848 1.00 6.18 ? 519 PHE B O 1 ATOM 8890 C CB . PHE B 1 519 ? 39.151 47.238 41.805 1.00 2.45 ? 519 PHE B CB 1 ATOM 8891 C CG . PHE B 1 519 ? 39.291 45.774 41.523 1.00 2.19 ? 519 PHE B CG 1 ATOM 8892 C CD1 . PHE B 1 519 ? 38.713 44.844 42.377 1.00 2.00 ? 519 PHE B CD1 1 ATOM 8893 C CD2 . PHE B 1 519 ? 39.921 45.324 40.368 1.00 2.66 ? 519 PHE B CD2 1 ATOM 8894 C CE1 . PHE B 1 519 ? 38.750 43.490 42.086 1.00 2.00 ? 519 PHE B CE1 1 ATOM 8895 C CE2 . PHE B 1 519 ? 39.964 43.963 40.066 1.00 2.81 ? 519 PHE B CE2 1 ATOM 8896 C CZ . PHE B 1 519 ? 39.374 43.045 40.930 1.00 2.14 ? 519 PHE B CZ 1 ATOM 8897 N N . GLN B 1 520 ? 37.810 50.032 42.478 1.00 6.62 ? 520 GLN B N 1 ATOM 8898 C CA . GLN B 1 520 ? 37.555 51.135 43.405 1.00 7.01 ? 520 GLN B CA 1 ATOM 8899 C C . GLN B 1 520 ? 36.070 51.132 43.793 1.00 6.99 ? 520 GLN B C 1 ATOM 8900 O O . GLN B 1 520 ? 35.703 51.173 44.973 1.00 4.47 ? 520 GLN B O 1 ATOM 8901 C CB . GLN B 1 520 ? 37.896 52.468 42.732 1.00 9.32 ? 520 GLN B CB 1 ATOM 8902 C CG . GLN B 1 520 ? 37.040 53.646 43.191 1.00 13.37 ? 520 GLN B CG 1 ATOM 8903 C CD . GLN B 1 520 ? 36.848 54.687 42.099 1.00 15.45 ? 520 GLN B CD 1 ATOM 8904 O OE1 . GLN B 1 520 ? 35.718 55.036 41.751 1.00 17.36 ? 520 GLN B OE1 1 ATOM 8905 N NE2 . GLN B 1 520 ? 37.953 55.187 41.552 1.00 17.37 ? 520 GLN B NE2 1 ATOM 8906 N N . GLN B 1 521 ? 35.222 51.063 42.774 1.00 6.33 ? 521 GLN B N 1 ATOM 8907 C CA . GLN B 1 521 ? 33.786 51.090 42.969 1.00 5.08 ? 521 GLN B CA 1 ATOM 8908 C C . GLN B 1 521 ? 33.184 49.988 43.842 1.00 4.15 ? 521 GLN B C 1 ATOM 8909 O O . GLN B 1 521 ? 32.266 50.254 44.615 1.00 5.17 ? 521 GLN B O 1 ATOM 8910 C CB . GLN B 1 521 ? 33.112 51.162 41.597 1.00 4.09 ? 521 GLN B CB 1 ATOM 8911 C CG . GLN B 1 521 ? 33.361 52.514 40.950 1.00 5.91 ? 521 GLN B CG 1 ATOM 8912 C CD . GLN B 1 521 ? 32.842 52.629 39.533 1.00 8.19 ? 521 GLN B CD 1 ATOM 8913 O OE1 . GLN B 1 521 ? 31.738 52.173 39.222 1.00 10.84 ? 521 GLN B OE1 1 ATOM 8914 N NE2 . GLN B 1 521 ? 33.631 53.266 38.664 1.00 8.10 ? 521 GLN B NE2 1 ATOM 8915 N N . ILE B 1 522 ? 33.679 48.759 43.746 1.00 3.45 ? 522 ILE B N 1 ATOM 8916 C CA . ILE B 1 522 ? 33.117 47.701 44.584 1.00 2.79 ? 522 ILE B CA 1 ATOM 8917 C C . ILE B 1 522 ? 33.710 47.802 45.989 1.00 3.31 ? 522 ILE B C 1 ATOM 8918 O O . ILE B 1 522 ? 33.272 47.119 46.921 1.00 2.14 ? 522 ILE B O 1 ATOM 8919 C CB . ILE B 1 522 ? 33.386 46.285 43.999 1.00 3.37 ? 522 ILE B CB 1 ATOM 8920 C CG1 . ILE B 1 522 ? 34.891 46.015 43.912 1.00 2.72 ? 522 ILE B CG1 1 ATOM 8921 C CG2 . ILE B 1 522 ? 32.726 46.161 42.625 1.00 2.00 ? 522 ILE B CG2 1 ATOM 8922 C CD1 . ILE B 1 522 ? 35.230 44.617 43.447 1.00 2.00 ? 522 ILE B CD1 1 ATOM 8923 N N . ARG B 1 523 ? 34.705 48.676 46.126 1.00 2.69 ? 523 ARG B N 1 ATOM 8924 C CA . ARG B 1 523 ? 35.368 48.904 47.398 1.00 2.71 ? 523 ARG B CA 1 ATOM 8925 C C . ARG B 1 523 ? 34.789 50.147 48.085 1.00 5.96 ? 523 ARG B C 1 ATOM 8926 O O . ARG B 1 523 ? 34.646 50.169 49.307 1.00 8.39 ? 523 ARG B O 1 ATOM 8927 C CB . ARG B 1 523 ? 36.872 49.062 47.172 1.00 2.00 ? 523 ARG B CB 1 ATOM 8928 C CG . ARG B 1 523 ? 37.662 49.491 48.401 1.00 3.60 ? 523 ARG B CG 1 ATOM 8929 C CD . ARG B 1 523 ? 37.916 50.996 48.398 1.00 4.60 ? 523 ARG B CD 1 ATOM 8930 N NE . ARG B 1 523 ? 39.334 51.304 48.558 1.00 5.08 ? 523 ARG B NE 1 ATOM 8931 C CZ . ARG B 1 523 ? 39.892 52.469 48.244 1.00 5.51 ? 523 ARG B CZ 1 ATOM 8932 N NH1 . ARG B 1 523 ? 39.154 53.453 47.744 1.00 3.99 ? 523 ARG B NH1 1 ATOM 8933 N NH2 . ARG B 1 523 ? 41.193 52.643 48.428 1.00 5.69 ? 523 ARG B NH2 1 ATOM 8934 N N . ASP B 1 524 ? 34.450 51.177 47.308 1.00 4.39 ? 524 ASP B N 1 ATOM 8935 C CA . ASP B 1 524 ? 33.881 52.404 47.876 1.00 2.73 ? 524 ASP B CA 1 ATOM 8936 C C . ASP B 1 524 ? 32.374 52.287 48.065 1.00 2.00 ? 524 ASP B C 1 ATOM 8937 O O . ASP B 1 524 ? 31.791 52.982 48.891 1.00 2.32 ? 524 ASP B O 1 ATOM 8938 C CB . ASP B 1 524 ? 34.173 53.608 46.971 1.00 2.45 ? 524 ASP B CB 1 ATOM 8939 C CG . ASP B 1 524 ? 35.564 54.176 47.175 1.00 2.57 ? 524 ASP B CG 1 ATOM 8940 O OD1 . ASP B 1 524 ? 36.379 53.535 47.867 1.00 4.25 ? 524 ASP B OD1 1 ATOM 8941 O OD2 . ASP B 1 524 ? 35.850 55.265 46.641 1.00 2.78 ? 524 ASP B OD2 1 ATOM 8942 N N . GLY B 1 525 ? 31.749 51.404 47.295 1.00 2.66 ? 525 GLY B N 1 ATOM 8943 C CA . GLY B 1 525 ? 30.311 51.242 47.373 1.00 2.00 ? 525 GLY B CA 1 ATOM 8944 C C . GLY B 1 525 ? 29.825 50.065 48.190 1.00 3.03 ? 525 GLY B C 1 ATOM 8945 O O . GLY B 1 525 ? 28.613 49.813 48.234 1.00 2.77 ? 525 GLY B O 1 ATOM 8946 N N . ASP B 1 526 ? 30.750 49.349 48.834 1.00 2.34 ? 526 ASP B N 1 ATOM 8947 C CA . ASP B 1 526 ? 30.398 48.192 49.657 1.00 2.00 ? 526 ASP B CA 1 ATOM 8948 C C . ASP B 1 526 ? 30.245 48.602 51.111 1.00 2.00 ? 526 ASP B C 1 ATOM 8949 O O . ASP B 1 526 ? 31.215 48.976 51.755 1.00 2.00 ? 526 ASP B O 1 ATOM 8950 C CB . ASP B 1 526 ? 31.461 47.102 49.545 1.00 2.00 ? 526 ASP B CB 1 ATOM 8951 C CG . ASP B 1 526 ? 31.239 45.996 50.543 1.00 3.13 ? 526 ASP B CG 1 ATOM 8952 O OD1 . ASP B 1 526 ? 30.061 45.793 50.897 1.00 3.60 ? 526 ASP B OD1 1 ATOM 8953 O OD2 . ASP B 1 526 ? 32.216 45.336 50.970 1.00 2.45 ? 526 ASP B OD2 1 ATOM 8954 N N . ARG B 1 527 ? 29.024 48.514 51.627 1.00 2.00 ? 527 ARG B N 1 ATOM 8955 C CA . ARG B 1 527 ? 28.727 48.921 53.003 1.00 2.00 ? 527 ARG B CA 1 ATOM 8956 C C . ARG B 1 527 ? 29.426 48.077 54.047 1.00 2.00 ? 527 ARG B C 1 ATOM 8957 O O . ARG B 1 527 ? 29.533 48.482 55.209 1.00 2.00 ? 527 ARG B O 1 ATOM 8958 C CB . ARG B 1 527 ? 27.212 48.880 53.249 1.00 3.21 ? 527 ARG B CB 1 ATOM 8959 C CG . ARG B 1 527 ? 26.765 49.298 54.651 1.00 3.86 ? 527 ARG B CG 1 ATOM 8960 C CD . ARG B 1 527 ? 25.260 49.621 54.683 1.00 3.89 ? 527 ARG B CD 1 ATOM 8961 N NE . ARG B 1 527 ? 24.422 48.449 54.432 1.00 3.15 ? 527 ARG B NE 1 ATOM 8962 C CZ . ARG B 1 527 ? 23.957 47.640 55.383 1.00 3.43 ? 527 ARG B CZ 1 ATOM 8963 N NH1 . ARG B 1 527 ? 24.238 47.871 56.661 1.00 2.51 ? 527 ARG B NH1 1 ATOM 8964 N NH2 . ARG B 1 527 ? 23.216 46.587 55.057 1.00 3.11 ? 527 ARG B NH2 1 ATOM 8965 N N . PHE B 1 528 ? 29.898 46.904 53.628 1.00 2.95 ? 528 PHE B N 1 ATOM 8966 C CA . PHE B 1 528 ? 30.578 45.980 54.528 1.00 2.41 ? 528 PHE B CA 1 ATOM 8967 C C . PHE B 1 528 ? 32.082 45.898 54.282 1.00 2.63 ? 528 PHE B C 1 ATOM 8968 O O . PHE B 1 528 ? 32.732 44.950 54.728 1.00 3.04 ? 528 PHE B O 1 ATOM 8969 C CB . PHE B 1 528 ? 29.974 44.570 54.433 1.00 2.00 ? 528 PHE B CB 1 ATOM 8970 C CG . PHE B 1 528 ? 28.586 44.448 55.010 1.00 2.00 ? 528 PHE B CG 1 ATOM 8971 C CD1 . PHE B 1 528 ? 27.470 44.847 54.283 1.00 2.07 ? 528 PHE B CD1 1 ATOM 8972 C CD2 . PHE B 1 528 ? 28.393 43.913 56.271 1.00 2.00 ? 528 PHE B CD2 1 ATOM 8973 C CE1 . PHE B 1 528 ? 26.180 44.710 54.806 1.00 2.00 ? 528 PHE B CE1 1 ATOM 8974 C CE2 . PHE B 1 528 ? 27.105 43.773 56.801 1.00 2.76 ? 528 PHE B CE2 1 ATOM 8975 C CZ . PHE B 1 528 ? 26.000 44.172 56.064 1.00 2.00 ? 528 PHE B CZ 1 ATOM 8976 N N . TRP B 1 529 ? 32.642 46.869 53.568 1.00 2.00 ? 529 TRP B N 1 ATOM 8977 C CA . TRP B 1 529 ? 34.081 46.845 53.355 1.00 2.00 ? 529 TRP B CA 1 ATOM 8978 C C . TRP B 1 529 ? 34.621 46.791 54.786 1.00 2.00 ? 529 TRP B C 1 ATOM 8979 O O . TRP B 1 529 ? 34.187 47.557 55.639 1.00 2.00 ? 529 TRP B O 1 ATOM 8980 C CB . TRP B 1 529 ? 34.545 48.106 52.622 1.00 2.00 ? 529 TRP B CB 1 ATOM 8981 C CG . TRP B 1 529 ? 36.005 48.088 52.319 1.00 2.51 ? 529 TRP B CG 1 ATOM 8982 C CD1 . TRP B 1 529 ? 36.997 48.708 53.025 1.00 4.11 ? 529 TRP B CD1 1 ATOM 8983 C CD2 . TRP B 1 529 ? 36.658 47.336 51.293 1.00 3.63 ? 529 TRP B CD2 1 ATOM 8984 N NE1 . TRP B 1 529 ? 38.228 48.385 52.507 1.00 3.21 ? 529 TRP B NE1 1 ATOM 8985 C CE2 . TRP B 1 529 ? 38.049 47.542 51.442 1.00 2.93 ? 529 TRP B CE2 1 ATOM 8986 C CE3 . TRP B 1 529 ? 36.205 46.500 50.264 1.00 3.81 ? 529 TRP B CE3 1 ATOM 8987 C CZ2 . TRP B 1 529 ? 38.991 46.943 50.603 1.00 2.69 ? 529 TRP B CZ2 1 ATOM 8988 C CZ3 . TRP B 1 529 ? 37.147 45.900 49.428 1.00 4.21 ? 529 TRP B CZ3 1 ATOM 8989 C CH2 . TRP B 1 529 ? 38.524 46.127 49.605 1.00 3.10 ? 529 TRP B CH2 1 ATOM 8990 N N . TRP B 1 530 ? 35.536 45.869 55.057 1.00 2.05 ? 530 TRP B N 1 ATOM 8991 C CA . TRP B 1 530 ? 36.061 45.704 56.409 1.00 2.61 ? 530 TRP B CA 1 ATOM 8992 C C . TRP B 1 530 ? 36.535 46.979 57.106 1.00 3.15 ? 530 TRP B C 1 ATOM 8993 O O . TRP B 1 530 ? 36.225 47.204 58.281 1.00 2.97 ? 530 TRP B O 1 ATOM 8994 C CB . TRP B 1 530 ? 37.186 44.664 56.416 1.00 2.93 ? 530 TRP B CB 1 ATOM 8995 C CG . TRP B 1 530 ? 38.354 45.039 55.590 1.00 3.01 ? 530 TRP B CG 1 ATOM 8996 C CD1 . TRP B 1 530 ? 38.394 45.150 54.232 1.00 3.27 ? 530 TRP B CD1 1 ATOM 8997 C CD2 . TRP B 1 530 ? 39.655 45.397 56.065 1.00 2.62 ? 530 TRP B CD2 1 ATOM 8998 N NE1 . TRP B 1 530 ? 39.644 45.560 53.829 1.00 4.20 ? 530 TRP B NE1 1 ATOM 8999 C CE2 . TRP B 1 530 ? 40.438 45.719 54.934 1.00 3.13 ? 530 TRP B CE2 1 ATOM 9000 C CE3 . TRP B 1 530 ? 40.235 45.478 57.336 1.00 2.00 ? 530 TRP B CE3 1 ATOM 9001 C CZ2 . TRP B 1 530 ? 41.773 46.120 55.035 1.00 2.38 ? 530 TRP B CZ2 1 ATOM 9002 C CZ3 . TRP B 1 530 ? 41.561 45.876 57.436 1.00 2.00 ? 530 TRP B CZ3 1 ATOM 9003 C CH2 . TRP B 1 530 ? 42.316 46.191 56.291 1.00 2.00 ? 530 TRP B CH2 1 ATOM 9004 N N . GLU B 1 531 ? 37.279 47.815 56.395 1.00 3.36 ? 531 GLU B N 1 ATOM 9005 C CA . GLU B 1 531 ? 37.779 49.043 56.990 1.00 3.28 ? 531 GLU B CA 1 ATOM 9006 C C . GLU B 1 531 ? 36.709 50.064 57.333 1.00 4.85 ? 531 GLU B C 1 ATOM 9007 O O . GLU B 1 531 ? 36.916 50.899 58.209 1.00 6.52 ? 531 GLU B O 1 ATOM 9008 C CB . GLU B 1 531 ? 38.813 49.689 56.082 1.00 4.15 ? 531 GLU B CB 1 ATOM 9009 C CG . GLU B 1 531 ? 40.169 49.048 56.188 1.00 6.79 ? 531 GLU B CG 1 ATOM 9010 C CD . GLU B 1 531 ? 41.245 49.908 55.571 1.00 9.20 ? 531 GLU B CD 1 ATOM 9011 O OE1 . GLU B 1 531 ? 41.230 50.074 54.329 1.00 9.44 ? 531 GLU B OE1 1 ATOM 9012 O OE2 . GLU B 1 531 ? 42.096 50.427 56.334 1.00 10.54 ? 531 GLU B OE2 1 ATOM 9013 N N . ASN B 1 532 ? 35.571 50.020 56.651 1.00 4.44 ? 532 ASN B N 1 ATOM 9014 C CA . ASN B 1 532 ? 34.510 50.971 56.951 1.00 3.61 ? 532 ASN B CA 1 ATOM 9015 C C . ASN B 1 532 ? 34.053 50.804 58.397 1.00 3.07 ? 532 ASN B C 1 ATOM 9016 O O . ASN B 1 532 ? 33.697 49.708 58.827 1.00 3.96 ? 532 ASN B O 1 ATOM 9017 C CB . ASN B 1 532 ? 33.322 50.769 56.027 1.00 3.78 ? 532 ASN B CB 1 ATOM 9018 C CG . ASN B 1 532 ? 32.161 51.661 56.392 1.00 5.19 ? 532 ASN B CG 1 ATOM 9019 O OD1 . ASN B 1 532 ? 32.262 52.891 56.350 1.00 4.62 ? 532 ASN B OD1 1 ATOM 9020 N ND2 . ASN B 1 532 ? 31.047 51.047 56.767 1.00 7.51 ? 532 ASN B ND2 1 ATOM 9021 N N . PRO B 1 533 ? 34.057 51.896 59.169 1.00 2.00 ? 533 PRO B N 1 ATOM 9022 C CA . PRO B 1 533 ? 33.646 51.867 60.575 1.00 2.00 ? 533 PRO B CA 1 ATOM 9023 C C . PRO B 1 533 ? 32.334 51.124 60.859 1.00 2.00 ? 533 PRO B C 1 ATOM 9024 O O . PRO B 1 533 ? 31.324 51.357 60.193 1.00 2.00 ? 533 PRO B O 1 ATOM 9025 C CB . PRO B 1 533 ? 33.564 53.347 60.925 1.00 2.53 ? 533 PRO B CB 1 ATOM 9026 C CG . PRO B 1 533 ? 34.671 53.936 60.089 1.00 2.00 ? 533 PRO B CG 1 ATOM 9027 C CD . PRO B 1 533 ? 34.458 53.256 58.764 1.00 2.00 ? 533 PRO B CD 1 ATOM 9028 N N . GLY B 1 534 ? 32.358 50.226 61.843 1.00 2.00 ? 534 GLY B N 1 ATOM 9029 C CA . GLY B 1 534 ? 31.158 49.486 62.204 1.00 2.67 ? 534 GLY B CA 1 ATOM 9030 C C . GLY B 1 534 ? 31.096 48.011 61.832 1.00 4.38 ? 534 GLY B C 1 ATOM 9031 O O . GLY B 1 534 ? 30.566 47.198 62.602 1.00 4.15 ? 534 GLY B O 1 ATOM 9032 N N . VAL B 1 535 ? 31.629 47.665 60.658 1.00 3.48 ? 535 VAL B N 1 ATOM 9033 C CA . VAL B 1 535 ? 31.629 46.290 60.152 1.00 2.28 ? 535 VAL B CA 1 ATOM 9034 C C . VAL B 1 535 ? 32.449 45.344 61.024 1.00 2.98 ? 535 VAL B C 1 ATOM 9035 O O . VAL B 1 535 ? 32.140 44.156 61.136 1.00 2.07 ? 535 VAL B O 1 ATOM 9036 C CB . VAL B 1 535 ? 32.172 46.249 58.725 1.00 2.27 ? 535 VAL B CB 1 ATOM 9037 C CG1 . VAL B 1 535 ? 32.154 44.833 58.207 1.00 2.31 ? 535 VAL B CG1 1 ATOM 9038 C CG2 . VAL B 1 535 ? 31.339 47.161 57.834 1.00 3.03 ? 535 VAL B CG2 1 ATOM 9039 N N . PHE B 1 536 ? 33.517 45.886 61.603 1.00 4.16 ? 536 PHE B N 1 ATOM 9040 C CA . PHE B 1 536 ? 34.402 45.172 62.529 1.00 3.96 ? 536 PHE B CA 1 ATOM 9041 C C . PHE B 1 536 ? 34.833 46.272 63.504 1.00 4.29 ? 536 PHE B C 1 ATOM 9042 O O . PHE B 1 536 ? 34.566 47.454 63.258 1.00 4.82 ? 536 PHE B O 1 ATOM 9043 C CB . PHE B 1 536 ? 35.659 44.613 61.842 1.00 3.57 ? 536 PHE B CB 1 ATOM 9044 C CG . PHE B 1 536 ? 35.401 43.479 60.887 1.00 2.00 ? 536 PHE B CG 1 ATOM 9045 C CD1 . PHE B 1 536 ? 35.213 43.719 59.538 1.00 2.35 ? 536 PHE B CD1 1 ATOM 9046 C CD2 . PHE B 1 536 ? 35.378 42.170 61.332 1.00 2.09 ? 536 PHE B CD2 1 ATOM 9047 C CE1 . PHE B 1 536 ? 35.009 42.670 58.647 1.00 2.32 ? 536 PHE B CE1 1 ATOM 9048 C CE2 . PHE B 1 536 ? 35.172 41.117 60.441 1.00 2.02 ? 536 PHE B CE2 1 ATOM 9049 C CZ . PHE B 1 536 ? 34.989 41.371 59.100 1.00 2.00 ? 536 PHE B CZ 1 ATOM 9050 N N . THR B 1 537 ? 35.499 45.907 64.596 1.00 3.91 ? 537 THR B N 1 ATOM 9051 C CA . THR B 1 537 ? 35.942 46.919 65.552 1.00 4.65 ? 537 THR B CA 1 ATOM 9052 C C . THR B 1 537 ? 37.440 47.192 65.430 1.00 7.45 ? 537 THR B C 1 ATOM 9053 O O . THR B 1 537 ? 38.161 46.439 64.774 1.00 7.47 ? 537 THR B O 1 ATOM 9054 C CB . THR B 1 537 ? 35.653 46.508 66.995 1.00 2.49 ? 537 THR B CB 1 ATOM 9055 O OG1 . THR B 1 537 ? 36.850 45.997 67.590 1.00 3.45 ? 537 THR B OG1 1 ATOM 9056 C CG2 . THR B 1 537 ? 34.573 45.450 67.035 1.00 2.79 ? 537 THR B CG2 1 ATOM 9057 N N . GLU B 1 538 ? 37.896 48.270 66.070 1.00 9.83 ? 538 GLU B N 1 ATOM 9058 C CA . GLU B 1 538 ? 39.303 48.674 66.034 1.00 10.98 ? 538 GLU B CA 1 ATOM 9059 C C . GLU B 1 538 ? 40.227 47.510 66.329 1.00 10.92 ? 538 GLU B C 1 ATOM 9060 O O . GLU B 1 538 ? 41.250 47.339 65.670 1.00 10.34 ? 538 GLU B O 1 ATOM 9061 C CB . GLU B 1 538 ? 39.580 49.797 67.052 1.00 15.48 ? 538 GLU B CB 1 ATOM 9062 C CG . GLU B 1 538 ? 41.033 50.336 67.034 1.00 19.61 ? 538 GLU B CG 1 ATOM 9063 C CD . GLU B 1 538 ? 41.362 51.271 68.205 1.00 20.45 ? 538 GLU B CD 1 ATOM 9064 O OE1 . GLU B 1 538 ? 40.520 52.126 68.549 1.00 22.79 ? 538 GLU B OE1 1 ATOM 9065 O OE2 . GLU B 1 538 ? 42.472 51.162 68.771 1.00 20.40 ? 538 GLU B OE2 1 ATOM 9066 N N . LYS B 1 539 ? 39.872 46.708 67.322 1.00 10.69 ? 539 LYS B N 1 ATOM 9067 C CA . LYS B 1 539 ? 40.712 45.580 67.682 1.00 12.49 ? 539 LYS B CA 1 ATOM 9068 C C . LYS B 1 539 ? 40.585 44.388 66.747 1.00 13.22 ? 539 LYS B C 1 ATOM 9069 O O . LYS B 1 539 ? 41.550 43.639 66.569 1.00 15.66 ? 539 LYS B O 1 ATOM 9070 C CB . LYS B 1 539 ? 40.441 45.147 69.123 1.00 13.24 ? 539 LYS B CB 1 ATOM 9071 C CG . LYS B 1 539 ? 41.593 45.465 70.070 1.00 14.03 ? 539 LYS B CG 1 ATOM 9072 C CD . LYS B 1 539 ? 41.202 45.238 71.519 1.00 14.60 ? 539 LYS B CD 1 ATOM 9073 C CE . LYS B 1 539 ? 40.672 43.828 71.739 1.00 15.90 ? 539 LYS B CE 1 ATOM 9074 N NZ . LYS B 1 539 ? 41.154 43.246 73.032 1.00 16.58 ? 539 LYS B NZ 1 ATOM 9075 N N . GLN B 1 540 ? 39.415 44.192 66.147 1.00 11.90 ? 540 GLN B N 1 ATOM 9076 C CA . GLN B 1 540 ? 39.269 43.072 65.229 1.00 10.63 ? 540 GLN B CA 1 ATOM 9077 C C . GLN B 1 540 ? 40.091 43.366 63.985 1.00 9.80 ? 540 GLN B C 1 ATOM 9078 O O . GLN B 1 540 ? 40.758 42.483 63.458 1.00 10.19 ? 540 GLN B O 1 ATOM 9079 C CB . GLN B 1 540 ? 37.799 42.839 64.873 1.00 10.99 ? 540 GLN B CB 1 ATOM 9080 C CG . GLN B 1 540 ? 36.974 42.376 66.069 1.00 13.64 ? 540 GLN B CG 1 ATOM 9081 C CD . GLN B 1 540 ? 35.556 41.965 65.705 1.00 14.53 ? 540 GLN B CD 1 ATOM 9082 O OE1 . GLN B 1 540 ? 34.832 42.707 65.032 1.00 15.80 ? 540 GLN B OE1 1 ATOM 9083 N NE2 . GLN B 1 540 ? 35.145 40.783 66.164 1.00 14.74 ? 540 GLN B NE2 1 ATOM 9084 N N . ARG B 1 541 ? 40.060 44.617 63.533 1.00 9.38 ? 541 ARG B N 1 ATOM 9085 C CA . ARG B 1 541 ? 40.824 45.029 62.358 1.00 9.67 ? 541 ARG B CA 1 ATOM 9086 C C . ARG B 1 541 ? 42.312 44.840 62.586 1.00 10.03 ? 541 ARG B C 1 ATOM 9087 O O . ARG B 1 541 ? 43.005 44.213 61.782 1.00 9.34 ? 541 ARG B O 1 ATOM 9088 C CB . ARG B 1 541 ? 40.558 46.500 62.023 1.00 8.96 ? 541 ARG B CB 1 ATOM 9089 C CG . ARG B 1 541 ? 39.270 46.730 61.272 1.00 8.69 ? 541 ARG B CG 1 ATOM 9090 C CD . ARG B 1 541 ? 39.323 48.026 60.502 1.00 9.32 ? 541 ARG B CD 1 ATOM 9091 N NE . ARG B 1 541 ? 39.273 49.197 61.369 1.00 11.60 ? 541 ARG B NE 1 ATOM 9092 C CZ . ARG B 1 541 ? 38.227 49.524 62.125 1.00 13.05 ? 541 ARG B CZ 1 ATOM 9093 N NH1 . ARG B 1 541 ? 37.134 48.765 62.128 1.00 12.79 ? 541 ARG B NH1 1 ATOM 9094 N NH2 . ARG B 1 541 ? 38.265 50.624 62.867 1.00 13.64 ? 541 ARG B NH2 1 ATOM 9095 N N . ASP B 1 542 ? 42.806 45.402 63.683 1.00 10.44 ? 542 ASP B N 1 ATOM 9096 C CA . ASP B 1 542 ? 44.212 45.286 64.005 1.00 12.16 ? 542 ASP B CA 1 ATOM 9097 C C . ASP B 1 542 ? 44.715 43.876 63.764 1.00 11.34 ? 542 ASP B C 1 ATOM 9098 O O . ASP B 1 542 ? 45.783 43.660 63.186 1.00 9.91 ? 542 ASP B O 1 ATOM 9099 C CB . ASP B 1 542 ? 44.460 45.690 65.451 1.00 16.14 ? 542 ASP B CB 1 ATOM 9100 C CG . ASP B 1 542 ? 44.949 47.110 65.562 1.00 19.15 ? 542 ASP B CG 1 ATOM 9101 O OD1 . ASP B 1 542 ? 45.562 47.568 64.569 1.00 19.86 ? 542 ASP B OD1 1 ATOM 9102 O OD2 . ASP B 1 542 ? 44.742 47.762 66.613 1.00 20.68 ? 542 ASP B OD2 1 ATOM 9103 N N . SER B 1 543 ? 43.922 42.912 64.204 1.00 10.80 ? 543 SER B N 1 ATOM 9104 C CA . SER B 1 543 ? 44.268 41.509 64.049 1.00 10.84 ? 543 SER B CA 1 ATOM 9105 C C . SER B 1 543 ? 44.196 41.087 62.577 1.00 9.20 ? 543 SER B C 1 ATOM 9106 O O . SER B 1 543 ? 44.943 40.213 62.136 1.00 9.26 ? 543 SER B O 1 ATOM 9107 C CB . SER B 1 543 ? 43.310 40.649 64.896 1.00 10.90 ? 543 SER B CB 1 ATOM 9108 O OG . SER B 1 543 ? 43.713 39.289 64.932 1.00 11.09 ? 543 SER B OG 1 ATOM 9109 N N . LEU B 1 544 ? 43.308 41.719 61.815 1.00 7.87 ? 544 LEU B N 1 ATOM 9110 C CA . LEU B 1 544 ? 43.138 41.349 60.421 1.00 6.50 ? 544 LEU B CA 1 ATOM 9111 C C . LEU B 1 544 ? 44.241 41.793 59.498 1.00 8.15 ? 544 LEU B C 1 ATOM 9112 O O . LEU B 1 544 ? 44.446 41.173 58.461 1.00 9.71 ? 544 LEU B O 1 ATOM 9113 C CB . LEU B 1 544 ? 41.797 41.854 59.879 1.00 3.83 ? 544 LEU B CB 1 ATOM 9114 C CG . LEU B 1 544 ? 40.537 41.116 60.327 1.00 2.31 ? 544 LEU B CG 1 ATOM 9115 C CD1 . LEU B 1 544 ? 39.343 41.932 59.918 1.00 2.00 ? 544 LEU B CD1 1 ATOM 9116 C CD2 . LEU B 1 544 ? 40.480 39.725 59.726 1.00 2.00 ? 544 LEU B CD2 1 ATOM 9117 N N . GLN B 1 545 ? 44.966 42.850 59.836 1.00 8.06 ? 545 GLN B N 1 ATOM 9118 C CA . GLN B 1 545 ? 46.007 43.254 58.903 1.00 8.03 ? 545 GLN B CA 1 ATOM 9119 C C . GLN B 1 545 ? 47.145 42.245 58.822 1.00 6.28 ? 545 GLN B C 1 ATOM 9120 O O . GLN B 1 545 ? 47.956 42.291 57.898 1.00 3.62 ? 545 GLN B O 1 ATOM 9121 C CB . GLN B 1 545 ? 46.544 44.640 59.238 1.00 11.80 ? 545 GLN B CB 1 ATOM 9122 C CG . GLN B 1 545 ? 46.171 45.152 60.593 1.00 18.84 ? 545 GLN B CG 1 ATOM 9123 C CD . GLN B 1 545 ? 46.817 46.494 60.860 1.00 21.70 ? 545 GLN B CD 1 ATOM 9124 O OE1 . GLN B 1 545 ? 46.329 47.547 60.438 1.00 24.23 ? 545 GLN B OE1 1 ATOM 9125 N NE2 . GLN B 1 545 ? 47.956 46.467 61.543 1.00 21.81 ? 545 GLN B NE2 1 ATOM 9126 N N . LYS B 1 546 ? 47.173 41.308 59.766 1.00 5.31 ? 546 LYS B N 1 ATOM 9127 C CA . LYS B 1 546 ? 48.225 40.299 59.803 1.00 5.41 ? 546 LYS B CA 1 ATOM 9128 C C . LYS B 1 546 ? 47.966 39.031 58.997 1.00 5.97 ? 546 LYS B C 1 ATOM 9129 O O . LYS B 1 546 ? 48.808 38.130 58.993 1.00 7.01 ? 546 LYS B O 1 ATOM 9130 C CB . LYS B 1 546 ? 48.557 39.906 61.252 1.00 6.92 ? 546 LYS B CB 1 ATOM 9131 C CG . LYS B 1 546 ? 49.202 41.010 62.104 1.00 8.59 ? 546 LYS B CG 1 ATOM 9132 C CD . LYS B 1 546 ? 49.675 40.460 63.458 1.00 10.44 ? 546 LYS B CD 1 ATOM 9133 C CE . LYS B 1 546 ? 49.601 41.505 64.581 1.00 12.44 ? 546 LYS B CE 1 ATOM 9134 N NZ . LYS B 1 546 ? 50.419 42.738 64.359 1.00 13.76 ? 546 LYS B NZ 1 ATOM 9135 N N . VAL B 1 547 ? 46.827 38.932 58.318 1.00 3.40 ? 547 VAL B N 1 ATOM 9136 C CA . VAL B 1 547 ? 46.592 37.727 57.525 1.00 2.64 ? 547 VAL B CA 1 ATOM 9137 C C . VAL B 1 547 ? 47.572 37.696 56.357 1.00 2.00 ? 547 VAL B C 1 ATOM 9138 O O . VAL B 1 547 ? 48.225 38.696 56.062 1.00 2.00 ? 547 VAL B O 1 ATOM 9139 C CB . VAL B 1 547 ? 45.153 37.646 56.953 1.00 2.00 ? 547 VAL B CB 1 ATOM 9140 C CG1 . VAL B 1 547 ? 44.234 36.977 57.936 1.00 2.00 ? 547 VAL B CG1 1 ATOM 9141 C CG2 . VAL B 1 547 ? 44.646 39.016 56.624 1.00 2.00 ? 547 VAL B CG2 1 ATOM 9142 N N . SER B 1 548 ? 47.668 36.536 55.712 1.00 2.52 ? 548 SER B N 1 ATOM 9143 C CA . SER B 1 548 ? 48.544 36.323 54.560 1.00 2.05 ? 548 SER B CA 1 ATOM 9144 C C . SER B 1 548 ? 48.167 35.005 53.905 1.00 2.00 ? 548 SER B C 1 ATOM 9145 O O . SER B 1 548 ? 47.706 34.092 54.584 1.00 2.00 ? 548 SER B O 1 ATOM 9146 C CB . SER B 1 548 ? 50.000 36.259 55.006 1.00 2.12 ? 548 SER B CB 1 ATOM 9147 O OG . SER B 1 548 ? 50.122 35.442 56.155 1.00 2.00 ? 548 SER B OG 1 ATOM 9148 N N . PHE B 1 549 ? 48.355 34.900 52.593 1.00 2.73 ? 549 PHE B N 1 ATOM 9149 C CA . PHE B 1 549 ? 48.019 33.656 51.917 1.00 2.00 ? 549 PHE B CA 1 ATOM 9150 C C . PHE B 1 549 ? 48.995 32.584 52.377 1.00 2.00 ? 549 PHE B C 1 ATOM 9151 O O . PHE B 1 549 ? 48.658 31.402 52.439 1.00 2.24 ? 549 PHE B O 1 ATOM 9152 C CB . PHE B 1 549 ? 48.079 33.798 50.393 1.00 2.00 ? 549 PHE B CB 1 ATOM 9153 C CG . PHE B 1 549 ? 47.342 32.714 49.683 1.00 2.00 ? 549 PHE B CG 1 ATOM 9154 C CD1 . PHE B 1 549 ? 45.963 32.631 49.777 1.00 2.00 ? 549 PHE B CD1 1 ATOM 9155 C CD2 . PHE B 1 549 ? 48.023 31.711 49.027 1.00 2.00 ? 549 PHE B CD2 1 ATOM 9156 C CE1 . PHE B 1 549 ? 45.275 31.559 49.236 1.00 2.00 ? 549 PHE B CE1 1 ATOM 9157 C CE2 . PHE B 1 549 ? 47.344 30.633 48.483 1.00 2.09 ? 549 PHE B CE2 1 ATOM 9158 C CZ . PHE B 1 549 ? 45.964 30.556 48.589 1.00 2.00 ? 549 PHE B CZ 1 ATOM 9159 N N . SER B 1 550 ? 50.206 33.006 52.715 1.00 2.00 ? 550 SER B N 1 ATOM 9160 C CA . SER B 1 550 ? 51.219 32.079 53.192 1.00 2.65 ? 550 SER B CA 1 ATOM 9161 C C . SER B 1 550 ? 50.651 31.418 54.450 1.00 3.71 ? 550 SER B C 1 ATOM 9162 O O . SER B 1 550 ? 50.692 30.198 54.602 1.00 4.97 ? 550 SER B O 1 ATOM 9163 C CB . SER B 1 550 ? 52.505 32.837 53.531 1.00 2.36 ? 550 SER B CB 1 ATOM 9164 O OG . SER B 1 550 ? 52.674 33.970 52.686 1.00 2.58 ? 550 SER B OG 1 ATOM 9165 N N . ARG B 1 551 ? 50.100 32.233 55.345 1.00 3.40 ? 551 ARG B N 1 ATOM 9166 C CA . ARG B 1 551 ? 49.520 31.710 56.574 1.00 2.91 ? 551 ARG B CA 1 ATOM 9167 C C . ARG B 1 551 ? 48.356 30.786 56.258 1.00 2.03 ? 551 ARG B C 1 ATOM 9168 O O . ARG B 1 551 ? 48.129 29.812 56.965 1.00 2.00 ? 551 ARG B O 1 ATOM 9169 C CB . ARG B 1 551 ? 49.013 32.840 57.470 1.00 3.83 ? 551 ARG B CB 1 ATOM 9170 C CG . ARG B 1 551 ? 48.590 32.357 58.850 1.00 4.63 ? 551 ARG B CG 1 ATOM 9171 C CD . ARG B 1 551 ? 49.821 31.974 59.647 1.00 6.95 ? 551 ARG B CD 1 ATOM 9172 N NE . ARG B 1 551 ? 49.656 30.760 60.442 1.00 6.70 ? 551 ARG B NE 1 ATOM 9173 C CZ . ARG B 1 551 ? 50.661 30.141 61.060 1.00 6.27 ? 551 ARG B CZ 1 ATOM 9174 N NH1 . ARG B 1 551 ? 51.898 30.623 60.980 1.00 4.33 ? 551 ARG B NH1 1 ATOM 9175 N NH2 . ARG B 1 551 ? 50.434 29.028 61.744 1.00 5.49 ? 551 ARG B NH2 1 ATOM 9176 N N . LEU B 1 552 ? 47.608 31.097 55.202 1.00 2.03 ? 552 LEU B N 1 ATOM 9177 C CA . LEU B 1 552 ? 46.476 30.263 54.845 1.00 2.00 ? 552 LEU B CA 1 ATOM 9178 C C . LEU B 1 552 ? 46.974 28.870 54.593 1.00 2.12 ? 552 LEU B C 1 ATOM 9179 O O . LEU B 1 552 ? 46.292 27.902 54.919 1.00 2.98 ? 552 LEU B O 1 ATOM 9180 C CB . LEU B 1 552 ? 45.760 30.747 53.582 1.00 2.00 ? 552 LEU B CB 1 ATOM 9181 C CG . LEU B 1 552 ? 44.550 29.837 53.327 1.00 2.00 ? 552 LEU B CG 1 ATOM 9182 C CD1 . LEU B 1 552 ? 43.659 29.943 54.548 1.00 2.73 ? 552 LEU B CD1 1 ATOM 9183 C CD2 . LEU B 1 552 ? 43.777 30.208 52.068 1.00 2.00 ? 552 LEU B CD2 1 ATOM 9184 N N . ILE B 1 553 ? 48.167 28.769 54.012 1.00 2.00 ? 553 ILE B N 1 ATOM 9185 C CA . ILE B 1 553 ? 48.746 27.465 53.704 1.00 2.17 ? 553 ILE B CA 1 ATOM 9186 C C . ILE B 1 553 ? 49.134 26.714 54.973 1.00 2.20 ? 553 ILE B C 1 ATOM 9187 O O . ILE B 1 553 ? 48.734 25.565 55.175 1.00 2.00 ? 553 ILE B O 1 ATOM 9188 C CB . ILE B 1 553 ? 49.977 27.608 52.800 1.00 2.00 ? 553 ILE B CB 1 ATOM 9189 C CG1 . ILE B 1 553 ? 49.566 28.272 51.485 1.00 2.00 ? 553 ILE B CG1 1 ATOM 9190 C CG2 . ILE B 1 553 ? 50.580 26.253 52.542 1.00 2.00 ? 553 ILE B CG2 1 ATOM 9191 C CD1 . ILE B 1 553 ? 50.706 28.523 50.524 1.00 2.00 ? 553 ILE B CD1 1 ATOM 9192 N N . CYS B 1 554 ? 49.897 27.388 55.825 1.00 2.00 ? 554 CYS B N 1 ATOM 9193 C CA . CYS B 1 554 ? 50.375 26.834 57.083 1.00 2.00 ? 554 CYS B CA 1 ATOM 9194 C C . CYS B 1 554 ? 49.321 26.243 58.016 1.00 2.00 ? 554 CYS B C 1 ATOM 9195 O O . CYS B 1 554 ? 49.618 25.348 58.803 1.00 2.22 ? 554 CYS B O 1 ATOM 9196 C CB . CYS B 1 554 ? 51.122 27.912 57.844 1.00 2.86 ? 554 CYS B CB 1 ATOM 9197 S SG . CYS B 1 554 ? 52.666 28.431 57.052 1.00 2.46 ? 554 CYS B SG 1 ATOM 9198 N N . ASP B 1 555 ? 48.099 26.749 57.949 1.00 2.09 ? 555 ASP B N 1 ATOM 9199 C CA . ASP B 1 555 ? 47.054 26.263 58.832 1.00 2.67 ? 555 ASP B CA 1 ATOM 9200 C C . ASP B 1 555 ? 46.161 25.167 58.252 1.00 4.63 ? 555 ASP B C 1 ATOM 9201 O O . ASP B 1 555 ? 45.451 24.495 59.010 1.00 5.32 ? 555 ASP B O 1 ATOM 9202 C CB . ASP B 1 555 ? 46.168 27.426 59.300 1.00 2.41 ? 555 ASP B CB 1 ATOM 9203 C CG . ASP B 1 555 ? 46.929 28.459 60.120 1.00 3.30 ? 555 ASP B CG 1 ATOM 9204 O OD1 . ASP B 1 555 ? 47.866 28.065 60.845 1.00 3.23 ? 555 ASP B OD1 1 ATOM 9205 O OD2 . ASP B 1 555 ? 46.575 29.662 60.056 1.00 3.35 ? 555 ASP B OD2 1 ATOM 9206 N N . ASN B 1 556 ? 46.194 24.958 56.936 1.00 3.28 ? 556 ASN B N 1 ATOM 9207 C CA . ASN B 1 556 ? 45.318 23.950 56.344 1.00 2.69 ? 556 ASN B CA 1 ATOM 9208 C C . ASN B 1 556 ? 45.946 22.889 55.450 1.00 2.00 ? 556 ASN B C 1 ATOM 9209 O O . ASN B 1 556 ? 45.264 22.290 54.621 1.00 2.79 ? 556 ASN B O 1 ATOM 9210 C CB . ASN B 1 556 ? 44.188 24.656 55.594 1.00 3.62 ? 556 ASN B CB 1 ATOM 9211 C CG . ASN B 1 556 ? 43.306 25.476 56.520 1.00 3.04 ? 556 ASN B CG 1 ATOM 9212 O OD1 . ASN B 1 556 ? 42.379 24.951 57.146 1.00 3.49 ? 556 ASN B OD1 1 ATOM 9213 N ND2 . ASN B 1 556 ? 43.606 26.766 56.629 1.00 2.00 ? 556 ASN B ND2 1 ATOM 9214 N N . THR B 1 557 ? 47.235 22.642 55.628 1.00 2.00 ? 557 THR B N 1 ATOM 9215 C CA . THR B 1 557 ? 47.935 21.632 54.837 1.00 3.12 ? 557 THR B CA 1 ATOM 9216 C C . THR B 1 557 ? 49.093 21.107 55.681 1.00 2.65 ? 557 THR B C 1 ATOM 9217 O O . THR B 1 557 ? 49.185 21.415 56.869 1.00 3.47 ? 557 THR B O 1 ATOM 9218 C CB . THR B 1 557 ? 48.496 22.241 53.525 1.00 2.75 ? 557 THR B CB 1 ATOM 9219 O OG1 . THR B 1 557 ? 49.489 23.229 53.831 1.00 3.34 ? 557 THR B OG1 1 ATOM 9220 C CG2 . THR B 1 557 ? 47.390 22.908 52.734 1.00 3.88 ? 557 THR B CG2 1 ATOM 9221 N N . HIS B 1 558 ? 49.973 20.308 55.093 1.00 2.00 ? 558 HIS B N 1 ATOM 9222 C CA . HIS B 1 558 ? 51.117 19.837 55.852 1.00 2.00 ? 558 HIS B CA 1 ATOM 9223 C C . HIS B 1 558 ? 52.421 20.412 55.300 1.00 2.55 ? 558 HIS B C 1 ATOM 9224 O O . HIS B 1 558 ? 53.505 19.846 55.501 1.00 2.00 ? 558 HIS B O 1 ATOM 9225 C CB . HIS B 1 558 ? 51.150 18.314 55.904 1.00 3.91 ? 558 HIS B CB 1 ATOM 9226 C CG . HIS B 1 558 ? 50.013 17.722 56.677 1.00 4.34 ? 558 HIS B CG 1 ATOM 9227 N ND1 . HIS B 1 558 ? 48.920 17.142 56.067 1.00 4.81 ? 558 HIS B ND1 1 ATOM 9228 C CD2 . HIS B 1 558 ? 49.778 17.662 58.010 1.00 4.51 ? 558 HIS B CD2 1 ATOM 9229 C CE1 . HIS B 1 558 ? 48.061 16.753 56.991 1.00 5.50 ? 558 HIS B CE1 1 ATOM 9230 N NE2 . HIS B 1 558 ? 48.557 17.057 58.179 1.00 5.46 ? 558 HIS B NE2 1 ATOM 9231 N N . ILE B 1 559 ? 52.292 21.549 54.601 1.00 2.86 ? 559 ILE B N 1 ATOM 9232 C CA . ILE B 1 559 ? 53.445 22.269 54.068 1.00 2.97 ? 559 ILE B CA 1 ATOM 9233 C C . ILE B 1 559 ? 54.045 22.904 55.311 1.00 3.40 ? 559 ILE B C 1 ATOM 9234 O O . ILE B 1 559 ? 53.323 23.244 56.247 1.00 5.08 ? 559 ILE B O 1 ATOM 9235 C CB . ILE B 1 559 ? 53.069 23.385 53.066 1.00 2.08 ? 559 ILE B CB 1 ATOM 9236 C CG1 . ILE B 1 559 ? 52.666 22.792 51.708 1.00 2.00 ? 559 ILE B CG1 1 ATOM 9237 C CG2 . ILE B 1 559 ? 54.274 24.287 52.840 1.00 2.58 ? 559 ILE B CG2 1 ATOM 9238 C CD1 . ILE B 1 559 ? 51.271 22.218 51.650 1.00 2.00 ? 559 ILE B CD1 1 ATOM 9239 N N . THR B 1 560 ? 55.353 23.098 55.308 1.00 3.11 ? 560 THR B N 1 ATOM 9240 C CA . THR B 1 560 ? 56.039 23.603 56.485 1.00 2.08 ? 560 THR B CA 1 ATOM 9241 C C . THR B 1 560 ? 56.903 24.835 56.294 1.00 2.00 ? 560 THR B C 1 ATOM 9242 O O . THR B 1 560 ? 56.981 25.710 57.168 1.00 2.00 ? 560 THR B O 1 ATOM 9243 C CB . THR B 1 560 ? 56.896 22.472 57.022 1.00 3.30 ? 560 THR B CB 1 ATOM 9244 O OG1 . THR B 1 560 ? 56.065 21.586 57.779 1.00 2.85 ? 560 THR B OG1 1 ATOM 9245 C CG2 . THR B 1 560 ? 58.057 23.002 57.846 1.00 3.84 ? 560 THR B CG2 1 ATOM 9246 N N . LYS B 1 561 ? 57.586 24.849 55.155 1.00 3.30 ? 561 LYS B N 1 ATOM 9247 C CA . LYS B 1 561 ? 58.464 25.931 54.759 1.00 3.32 ? 561 LYS B CA 1 ATOM 9248 C C . LYS B 1 561 ? 57.646 26.627 53.675 1.00 2.62 ? 561 LYS B C 1 ATOM 9249 O O . LYS B 1 561 ? 57.127 25.970 52.768 1.00 2.00 ? 561 LYS B O 1 ATOM 9250 C CB . LYS B 1 561 ? 59.767 25.362 54.179 1.00 5.37 ? 561 LYS B CB 1 ATOM 9251 C CG . LYS B 1 561 ? 60.145 23.946 54.689 1.00 9.97 ? 561 LYS B CG 1 ATOM 9252 C CD . LYS B 1 561 ? 60.730 23.913 56.116 1.00 12.16 ? 561 LYS B CD 1 ATOM 9253 C CE . LYS B 1 561 ? 62.257 24.094 56.130 1.00 14.71 ? 561 LYS B CE 1 ATOM 9254 N NZ . LYS B 1 561 ? 62.709 25.435 55.634 1.00 17.47 ? 561 LYS B NZ 1 ATOM 9255 N N . VAL B 1 562 ? 57.502 27.943 53.797 1.00 2.30 ? 562 VAL B N 1 ATOM 9256 C CA . VAL B 1 562 ? 56.733 28.749 52.852 1.00 2.84 ? 562 VAL B CA 1 ATOM 9257 C C . VAL B 1 562 ? 57.290 30.169 52.765 1.00 3.30 ? 562 VAL B C 1 ATOM 9258 O O . VAL B 1 562 ? 57.942 30.648 53.693 1.00 3.97 ? 562 VAL B O 1 ATOM 9259 C CB . VAL B 1 562 ? 55.256 28.834 53.264 1.00 2.00 ? 562 VAL B CB 1 ATOM 9260 C CG1 . VAL B 1 562 ? 54.626 27.465 53.203 1.00 2.00 ? 562 VAL B CG1 1 ATOM 9261 C CG2 . VAL B 1 562 ? 55.137 29.422 54.663 1.00 2.00 ? 562 VAL B CG2 1 ATOM 9262 N N . PRO B 1 563 ? 57.012 30.869 51.655 1.00 3.55 ? 563 PRO B N 1 ATOM 9263 C CA . PRO B 1 563 ? 57.464 32.242 51.379 1.00 4.78 ? 563 PRO B CA 1 ATOM 9264 C C . PRO B 1 563 ? 56.730 33.328 52.150 1.00 6.69 ? 563 PRO B C 1 ATOM 9265 O O . PRO B 1 563 ? 55.562 33.156 52.497 1.00 7.45 ? 563 PRO B O 1 ATOM 9266 C CB . PRO B 1 563 ? 57.237 32.388 49.873 1.00 5.41 ? 563 PRO B CB 1 ATOM 9267 C CG . PRO B 1 563 ? 57.014 30.937 49.377 1.00 6.22 ? 563 PRO B CG 1 ATOM 9268 C CD . PRO B 1 563 ? 56.264 30.332 50.510 1.00 3.89 ? 563 PRO B CD 1 ATOM 9269 N N . LEU B 1 564 ? 57.410 34.445 52.416 1.00 7.38 ? 564 LEU B N 1 ATOM 9270 C CA . LEU B 1 564 ? 56.766 35.548 53.126 1.00 7.32 ? 564 LEU B CA 1 ATOM 9271 C C . LEU B 1 564 ? 55.862 36.216 52.103 1.00 8.70 ? 564 LEU B C 1 ATOM 9272 O O . LEU B 1 564 ? 54.762 36.652 52.431 1.00 10.65 ? 564 LEU B O 1 ATOM 9273 C CB . LEU B 1 564 ? 57.777 36.588 53.634 1.00 7.96 ? 564 LEU B CB 1 ATOM 9274 C CG . LEU B 1 564 ? 59.036 36.211 54.430 1.00 9.83 ? 564 LEU B CG 1 ATOM 9275 C CD1 . LEU B 1 564 ? 59.866 37.472 54.682 1.00 9.32 ? 564 LEU B CD1 1 ATOM 9276 C CD2 . LEU B 1 564 ? 58.664 35.548 55.750 1.00 9.51 ? 564 LEU B CD2 1 ATOM 9277 N N . HIS B 1 565 ? 56.316 36.281 50.855 1.00 7.27 ? 565 HIS B N 1 ATOM 9278 C CA . HIS B 1 565 ? 55.518 36.922 49.816 1.00 7.54 ? 565 HIS B CA 1 ATOM 9279 C C . HIS B 1 565 ? 55.071 35.956 48.712 1.00 7.67 ? 565 HIS B C 1 ATOM 9280 O O . HIS B 1 565 ? 55.640 35.919 47.621 1.00 6.91 ? 565 HIS B O 1 ATOM 9281 C CB . HIS B 1 565 ? 56.309 38.098 49.251 1.00 9.09 ? 565 HIS B CB 1 ATOM 9282 C CG . HIS B 1 565 ? 56.826 39.023 50.310 1.00 10.89 ? 565 HIS B CG 1 ATOM 9283 N ND1 . HIS B 1 565 ? 55.992 39.735 51.146 1.00 12.03 ? 565 HIS B ND1 1 ATOM 9284 C CD2 . HIS B 1 565 ? 58.089 39.315 50.703 1.00 11.83 ? 565 HIS B CD2 1 ATOM 9285 C CE1 . HIS B 1 565 ? 56.718 40.423 52.011 1.00 12.83 ? 565 HIS B CE1 1 ATOM 9286 N NE2 . HIS B 1 565 ? 57.994 40.186 51.764 1.00 12.82 ? 565 HIS B NE2 1 ATOM 9287 N N . ALA B 1 566 ? 54.022 35.194 49.016 1.00 6.80 ? 566 ALA B N 1 ATOM 9288 C CA . ALA B 1 566 ? 53.465 34.190 48.115 1.00 4.97 ? 566 ALA B CA 1 ATOM 9289 C C . ALA B 1 566 ? 53.207 34.629 46.689 1.00 4.75 ? 566 ALA B C 1 ATOM 9290 O O . ALA B 1 566 ? 53.035 33.785 45.814 1.00 5.07 ? 566 ALA B O 1 ATOM 9291 C CB . ALA B 1 566 ? 52.184 33.623 48.701 1.00 3.03 ? 566 ALA B CB 1 ATOM 9292 N N . PHE B 1 567 ? 53.177 35.928 46.427 1.00 5.69 ? 567 PHE B N 1 ATOM 9293 C CA . PHE B 1 567 ? 52.906 36.351 45.056 1.00 7.03 ? 567 PHE B CA 1 ATOM 9294 C C . PHE B 1 567 ? 54.092 36.651 44.131 1.00 6.20 ? 567 PHE B C 1 ATOM 9295 O O . PHE B 1 567 ? 53.901 36.860 42.941 1.00 5.07 ? 567 PHE B O 1 ATOM 9296 C CB . PHE B 1 567 ? 51.926 37.536 45.049 1.00 4.37 ? 567 PHE B CB 1 ATOM 9297 C CG . PHE B 1 567 ? 50.523 37.163 45.453 1.00 2.48 ? 567 PHE B CG 1 ATOM 9298 C CD1 . PHE B 1 567 ? 49.860 36.119 44.832 1.00 2.70 ? 567 PHE B CD1 1 ATOM 9299 C CD2 . PHE B 1 567 ? 49.864 37.859 46.451 1.00 2.61 ? 567 PHE B CD2 1 ATOM 9300 C CE1 . PHE B 1 567 ? 48.561 35.777 45.203 1.00 2.49 ? 567 PHE B CE1 1 ATOM 9301 C CE2 . PHE B 1 567 ? 48.564 37.520 46.823 1.00 2.00 ? 567 PHE B CE2 1 ATOM 9302 C CZ . PHE B 1 567 ? 47.916 36.479 46.198 1.00 2.00 ? 567 PHE B CZ 1 ATOM 9303 N N . GLN B 1 568 ? 55.312 36.670 44.643 1.00 7.34 ? 568 GLN B N 1 ATOM 9304 C CA . GLN B 1 568 ? 56.424 36.949 43.755 1.00 9.34 ? 568 GLN B CA 1 ATOM 9305 C C . GLN B 1 568 ? 57.291 35.713 43.554 1.00 11.52 ? 568 GLN B C 1 ATOM 9306 O O . GLN B 1 568 ? 57.135 34.724 44.272 1.00 13.40 ? 568 GLN B O 1 ATOM 9307 C CB . GLN B 1 568 ? 57.245 38.123 44.293 1.00 11.43 ? 568 GLN B CB 1 ATOM 9308 C CG . GLN B 1 568 ? 57.649 38.005 45.742 1.00 14.51 ? 568 GLN B CG 1 ATOM 9309 C CD . GLN B 1 568 ? 58.293 39.282 46.266 1.00 17.15 ? 568 GLN B CD 1 ATOM 9310 O OE1 . GLN B 1 568 ? 57.679 40.356 46.257 1.00 18.41 ? 568 GLN B OE1 1 ATOM 9311 N NE2 . GLN B 1 568 ? 59.538 39.171 46.727 1.00 18.11 ? 568 GLN B NE2 1 ATOM 9312 N N . ALA B 1 569 ? 58.183 35.766 42.562 1.00 11.71 ? 569 ALA B N 1 ATOM 9313 C CA . ALA B 1 569 ? 59.088 34.662 42.240 1.00 11.39 ? 569 ALA B CA 1 ATOM 9314 C C . ALA B 1 569 ? 59.978 34.225 43.415 1.00 12.67 ? 569 ALA B C 1 ATOM 9315 O O . ALA B 1 569 ? 60.743 35.032 43.950 1.00 14.18 ? 569 ALA B O 1 ATOM 9316 C CB . ALA B 1 569 ? 59.959 35.057 41.056 1.00 10.70 ? 569 ALA B CB 1 ATOM 9317 N N . ASN B 1 570 ? 59.875 32.949 43.801 1.00 12.94 ? 570 ASN B N 1 ATOM 9318 C CA . ASN B 1 570 ? 60.632 32.402 44.903 1.00 14.72 ? 570 ASN B CA 1 ATOM 9319 C C . ASN B 1 570 ? 61.204 31.051 44.567 1.00 16.61 ? 570 ASN B C 1 ATOM 9320 O O . ASN B 1 570 ? 60.670 30.289 43.757 1.00 18.12 ? 570 ASN B O 1 ATOM 9321 C CB . ASN B 1 570 ? 59.774 32.271 46.142 1.00 15.39 ? 570 ASN B CB 1 ATOM 9322 C CG . ASN B 1 570 ? 59.346 33.621 46.693 1.00 16.14 ? 570 ASN B CG 1 ATOM 9323 O OD1 . ASN B 1 570 ? 58.343 33.714 47.405 1.00 17.22 ? 570 ASN B OD1 1 ATOM 9324 N ND2 . ASN B 1 570 ? 60.082 34.672 46.352 1.00 16.47 ? 570 ASN B ND2 1 ATOM 9325 N N . ASN B 1 571 ? 62.566 30.942 44.861 1.00 15.45 ? 571 ASN B N 1 ATOM 9326 C CA . ASN B 1 571 ? 63.318 29.730 44.425 1.00 16.82 ? 571 ASN B CA 1 ATOM 9327 C C . ASN B 1 571 ? 63.039 28.703 45.595 1.00 17.12 ? 571 ASN B C 1 ATOM 9328 O O . ASN B 1 571 ? 62.182 29.085 46.380 1.00 16.13 ? 571 ASN B O 1 ATOM 9329 C CB . ASN B 1 571 ? 64.614 30.200 43.718 1.00 19.29 ? 571 ASN B CB 1 ATOM 9330 C CG . ASN B 1 571 ? 64.224 30.778 42.332 1.00 21.67 ? 571 ASN B CG 1 ATOM 9331 O OD1 . ASN B 1 571 ? 64.263 30.040 41.343 1.00 20.85 ? 571 ASN B OD1 1 ATOM 9332 N ND2 . ASN B 1 571 ? 63.883 32.065 42.294 1.00 22.58 ? 571 ASN B ND2 1 ATOM 9333 N N . TYR B 1 572 ? 63.585 27.417 45.813 1.00 18.19 ? 572 TYR B N 1 ATOM 9334 C CA . TYR B 1 572 ? 63.130 26.610 47.041 1.00 20.98 ? 572 TYR B CA 1 ATOM 9335 C C . TYR B 1 572 ? 63.988 26.886 48.301 1.00 24.80 ? 572 TYR B C 1 ATOM 9336 O O . TYR B 1 572 ? 63.441 27.514 49.200 1.00 28.36 ? 572 TYR B O 1 ATOM 9337 C CB . TYR B 1 572 ? 63.121 25.016 46.989 1.00 21.36 ? 572 TYR B CB 1 ATOM 9338 C CG . TYR B 1 572 ? 62.891 24.342 48.392 1.00 21.22 ? 572 TYR B CG 1 ATOM 9339 C CD1 . TYR B 1 572 ? 61.908 24.800 49.264 1.00 20.18 ? 572 TYR B CD1 1 ATOM 9340 C CD2 . TYR B 1 572 ? 63.655 23.264 48.835 1.00 21.22 ? 572 TYR B CD2 1 ATOM 9341 C CE1 . TYR B 1 572 ? 61.722 24.185 50.513 1.00 20.18 ? 572 TYR B CE1 1 ATOM 9342 C CE2 . TYR B 1 572 ? 63.485 22.644 50.089 1.00 22.30 ? 572 TYR B CE2 1 ATOM 9343 C CZ . TYR B 1 572 ? 62.498 23.127 50.912 1.00 22.08 ? 572 TYR B CZ 1 ATOM 9344 O OH . TYR B 1 572 ? 62.274 22.555 52.137 1.00 23.97 ? 572 TYR B OH 1 ATOM 9345 N N . PRO B 1 573 ? 65.349 26.495 48.495 1.00 24.04 ? 573 PRO B N 1 ATOM 9346 C CA . PRO B 1 573 ? 65.978 26.843 49.877 1.00 23.05 ? 573 PRO B CA 1 ATOM 9347 C C . PRO B 1 573 ? 66.020 28.113 50.610 1.00 24.85 ? 573 PRO B C 1 ATOM 9348 O O . PRO B 1 573 ? 65.893 28.131 51.842 1.00 25.51 ? 573 PRO B O 1 ATOM 9349 C CB . PRO B 1 573 ? 67.426 26.461 49.863 1.00 23.76 ? 573 PRO B CB 1 ATOM 9350 C CG . PRO B 1 573 ? 67.335 25.176 49.195 1.00 24.67 ? 573 PRO B CG 1 ATOM 9351 C CD . PRO B 1 573 ? 66.012 25.136 48.473 1.00 23.93 ? 573 PRO B CD 1 ATOM 9352 N N . HIS B 1 574 ? 66.207 29.161 49.905 1.00 25.34 ? 574 HIS B N 1 ATOM 9353 C CA . HIS B 1 574 ? 66.396 30.413 50.593 1.00 23.48 ? 574 HIS B CA 1 ATOM 9354 C C . HIS B 1 574 ? 65.180 31.221 50.850 1.00 21.27 ? 574 HIS B C 1 ATOM 9355 O O . HIS B 1 574 ? 64.963 31.718 51.969 1.00 20.89 ? 574 HIS B O 1 ATOM 9356 C CB . HIS B 1 574 ? 67.401 31.139 49.751 1.00 29.62 ? 574 HIS B CB 1 ATOM 9357 C CG . HIS B 1 574 ? 68.012 32.308 50.461 1.00 35.25 ? 574 HIS B CG 1 ATOM 9358 N ND1 . HIS B 1 574 ? 68.157 32.427 51.830 1.00 37.38 ? 574 HIS B ND1 1 ATOM 9359 C CD2 . HIS B 1 574 ? 68.536 33.435 49.930 1.00 36.79 ? 574 HIS B CD2 1 ATOM 9360 C CE1 . HIS B 1 574 ? 68.749 33.570 52.111 1.00 38.89 ? 574 HIS B CE1 1 ATOM 9361 N NE2 . HIS B 1 574 ? 68.992 34.204 50.977 1.00 39.73 ? 574 HIS B NE2 1 ATOM 9362 N N . ASP B 1 575 ? 64.397 31.361 49.813 1.00 18.07 ? 575 ASP B N 1 ATOM 9363 C CA . ASP B 1 575 ? 63.223 32.216 49.953 1.00 14.90 ? 575 ASP B CA 1 ATOM 9364 C C . ASP B 1 575 ? 62.127 31.657 50.856 1.00 13.12 ? 575 ASP B C 1 ATOM 9365 O O . ASP B 1 575 ? 61.123 32.326 51.122 1.00 14.02 ? 575 ASP B O 1 ATOM 9366 C CB . ASP B 1 575 ? 62.637 32.557 48.586 1.00 15.53 ? 575 ASP B CB 1 ATOM 9367 C CG . ASP B 1 575 ? 63.603 33.351 47.717 1.00 15.91 ? 575 ASP B CG 1 ATOM 9368 O OD1 . ASP B 1 575 ? 64.312 34.231 48.250 1.00 15.45 ? 575 ASP B OD1 1 ATOM 9369 O OD2 . ASP B 1 575 ? 63.644 33.104 46.494 1.00 17.23 ? 575 ASP B OD2 1 ATOM 9370 N N . PHE B 1 576 ? 62.332 30.436 51.333 1.00 11.47 ? 576 PHE B N 1 ATOM 9371 C CA . PHE B 1 576 ? 61.376 29.771 52.207 1.00 11.64 ? 576 PHE B CA 1 ATOM 9372 C C . PHE B 1 576 ? 61.783 29.813 53.682 1.00 12.22 ? 576 PHE B C 1 ATOM 9373 O O . PHE B 1 576 ? 62.970 29.847 54.015 1.00 12.58 ? 576 PHE B O 1 ATOM 9374 C CB . PHE B 1 576 ? 61.183 28.330 51.745 1.00 11.60 ? 576 PHE B CB 1 ATOM 9375 C CG . PHE B 1 576 ? 60.367 28.210 50.489 1.00 12.82 ? 576 PHE B CG 1 ATOM 9376 C CD1 . PHE B 1 576 ? 60.838 28.690 49.268 1.00 12.49 ? 576 PHE B CD1 1 ATOM 9377 C CD2 . PHE B 1 576 ? 59.103 27.634 50.532 1.00 14.03 ? 576 PHE B CD2 1 ATOM 9378 C CE1 . PHE B 1 576 ? 60.054 28.593 48.112 1.00 12.89 ? 576 PHE B CE1 1 ATOM 9379 C CE2 . PHE B 1 576 ? 58.315 27.534 49.387 1.00 13.56 ? 576 PHE B CE2 1 ATOM 9380 C CZ . PHE B 1 576 ? 58.790 28.013 48.176 1.00 13.28 ? 576 PHE B CZ 1 ATOM 9381 N N . VAL B 1 577 ? 60.778 29.807 54.557 1.00 11.37 ? 577 VAL B N 1 ATOM 9382 C CA . VAL B 1 577 ? 60.979 29.858 56.002 1.00 9.22 ? 577 VAL B CA 1 ATOM 9383 C C . VAL B 1 577 ? 59.946 28.997 56.702 1.00 8.84 ? 577 VAL B C 1 ATOM 9384 O O . VAL B 1 577 ? 58.807 28.908 56.256 1.00 7.92 ? 577 VAL B O 1 ATOM 9385 C CB . VAL B 1 577 ? 60.809 31.295 56.503 1.00 9.53 ? 577 VAL B CB 1 ATOM 9386 C CG1 . VAL B 1 577 ? 61.728 32.220 55.730 1.00 9.82 ? 577 VAL B CG1 1 ATOM 9387 C CG2 . VAL B 1 577 ? 59.357 31.735 56.328 1.00 8.47 ? 577 VAL B CG2 1 ATOM 9388 N N . ASP B 1 578 ? 60.314 28.360 57.802 1.00 9.28 ? 578 ASP B N 1 ATOM 9389 C CA . ASP B 1 578 ? 59.332 27.545 58.503 1.00 10.27 ? 578 ASP B CA 1 ATOM 9390 C C . ASP B 1 578 ? 58.160 28.422 58.964 1.00 8.92 ? 578 ASP B C 1 ATOM 9391 O O . ASP B 1 578 ? 58.364 29.545 59.406 1.00 7.15 ? 578 ASP B O 1 ATOM 9392 C CB . ASP B 1 578 ? 59.948 26.882 59.715 1.00 12.56 ? 578 ASP B CB 1 ATOM 9393 C CG . ASP B 1 578 ? 59.040 25.849 60.310 1.00 14.19 ? 578 ASP B CG 1 ATOM 9394 O OD1 . ASP B 1 578 ? 59.020 24.714 59.802 1.00 15.24 ? 578 ASP B OD1 1 ATOM 9395 O OD2 . ASP B 1 578 ? 58.324 26.180 61.268 1.00 14.33 ? 578 ASP B OD2 1 ATOM 9396 N N . CYS B 1 579 ? 56.939 27.906 58.889 1.00 8.88 ? 579 CYS B N 1 ATOM 9397 C CA . CYS B 1 579 ? 55.763 28.697 59.266 1.00 9.78 ? 579 CYS B CA 1 ATOM 9398 C C . CYS B 1 579 ? 55.828 29.564 60.531 1.00 11.50 ? 579 CYS B C 1 ATOM 9399 O O . CYS B 1 579 ? 55.173 30.607 60.599 1.00 13.31 ? 579 CYS B O 1 ATOM 9400 C CB . CYS B 1 579 ? 54.534 27.800 59.373 1.00 9.11 ? 579 CYS B CB 1 ATOM 9401 S SG . CYS B 1 579 ? 53.965 27.083 57.789 1.00 11.10 ? 579 CYS B SG 1 ATOM 9402 N N . SER B 1 580 ? 56.589 29.152 61.535 1.00 10.29 ? 580 SER B N 1 ATOM 9403 C CA . SER B 1 580 ? 56.660 29.934 62.765 1.00 9.63 ? 580 SER B CA 1 ATOM 9404 C C . SER B 1 580 ? 57.266 31.328 62.594 1.00 10.22 ? 580 SER B C 1 ATOM 9405 O O . SER B 1 580 ? 57.489 32.044 63.573 1.00 9.72 ? 580 SER B O 1 ATOM 9406 C CB . SER B 1 580 ? 57.451 29.159 63.801 1.00 9.93 ? 580 SER B CB 1 ATOM 9407 O OG . SER B 1 580 ? 58.658 28.693 63.223 1.00 10.73 ? 580 SER B OG 1 ATOM 9408 N N . ALA B 1 581 ? 57.541 31.717 61.357 1.00 9.52 ? 581 ALA B N 1 ATOM 9409 C CA . ALA B 1 581 ? 58.115 33.029 61.114 1.00 11.28 ? 581 ALA B CA 1 ATOM 9410 C C . ALA B 1 581 ? 57.095 33.938 60.544 1.00 13.64 ? 581 ALA B C 1 ATOM 9411 O O . ALA B 1 581 ? 57.384 35.037 60.098 1.00 13.77 ? 581 ALA B O 1 ATOM 9412 C CB . ALA B 1 581 ? 59.316 32.934 60.182 1.00 10.58 ? 581 ALA B CB 1 ATOM 9413 N N . ILE B 1 582 ? 55.913 33.424 60.564 1.00 14.34 ? 582 ILE B N 1 ATOM 9414 C CA . ILE B 1 582 ? 54.869 34.220 59.993 1.00 15.97 ? 582 ILE B CA 1 ATOM 9415 C C . ILE B 1 582 ? 53.663 34.355 60.879 1.00 18.85 ? 582 ILE B C 1 ATOM 9416 O O . ILE B 1 582 ? 53.239 33.417 61.551 1.00 18.87 ? 582 ILE B O 1 ATOM 9417 C CB . ILE B 1 582 ? 54.483 33.663 58.620 1.00 16.02 ? 582 ILE B CB 1 ATOM 9418 C CG1 . ILE B 1 582 ? 53.006 33.952 58.363 1.00 18.05 ? 582 ILE B CG1 1 ATOM 9419 C CG2 . ILE B 1 582 ? 54.764 32.163 58.553 1.00 15.05 ? 582 ILE B CG2 1 ATOM 9420 C CD1 . ILE B 1 582 ? 52.567 33.592 56.961 1.00 22.01 ? 582 ILE B CD1 1 ATOM 9421 N N . ASP B 1 583 ? 53.106 35.592 60.870 1.00 20.03 ? 583 ASP B N 1 ATOM 9422 C CA . ASP B 1 583 ? 51.945 36.052 61.677 1.00 19.92 ? 583 ASP B CA 1 ATOM 9423 C C . ASP B 1 583 ? 50.792 35.036 61.686 1.00 19.23 ? 583 ASP B C 1 ATOM 9424 O O . ASP B 1 583 ? 50.708 34.188 60.803 1.00 17.85 ? 583 ASP B O 1 ATOM 9425 C CB . ASP B 1 583 ? 51.473 37.438 61.217 1.00 22.86 ? 583 ASP B CB 1 ATOM 9426 C CG . ASP B 1 583 ? 52.458 38.551 61.601 1.00 24.18 ? 583 ASP B CG 1 ATOM 9427 O OD1 . ASP B 1 583 ? 53.684 38.287 61.636 1.00 24.53 ? 583 ASP B OD1 1 ATOM 9428 O OD2 . ASP B 1 583 ? 52.009 39.691 61.859 1.00 23.95 ? 583 ASP B OD2 1 ATOM 9429 N N . LYS B 1 584 ? 49.915 35.132 62.692 1.00 18.51 ? 584 LYS B N 1 ATOM 9430 C CA . LYS B 1 584 ? 48.851 34.137 62.892 1.00 17.47 ? 584 LYS B CA 1 ATOM 9431 C C . LYS B 1 584 ? 47.337 34.454 62.911 1.00 14.37 ? 584 LYS B C 1 ATOM 9432 O O . LYS B 1 584 ? 46.528 33.525 62.902 1.00 14.94 ? 584 LYS B O 1 ATOM 9433 C CB . LYS B 1 584 ? 49.206 33.386 64.187 1.00 20.41 ? 584 LYS B CB 1 ATOM 9434 C CG . LYS B 1 584 ? 48.423 32.118 64.492 1.00 23.71 ? 584 LYS B CG 1 ATOM 9435 C CD . LYS B 1 584 ? 48.745 31.006 63.504 1.00 25.27 ? 584 LYS B CD 1 ATOM 9436 C CE . LYS B 1 584 ? 48.291 29.655 64.043 1.00 26.85 ? 584 LYS B CE 1 ATOM 9437 N NZ . LYS B 1 584 ? 48.930 29.346 65.368 1.00 28.38 ? 584 LYS B NZ 1 ATOM 9438 N N . LEU B 1 585 ? 46.933 35.719 62.920 1.00 11.00 ? 585 LEU B N 1 ATOM 9439 C CA . LEU B 1 585 ? 45.496 36.056 62.996 1.00 8.35 ? 585 LEU B CA 1 ATOM 9440 C C . LEU B 1 585 ? 44.963 35.630 64.358 1.00 7.34 ? 585 LEU B C 1 ATOM 9441 O O . LEU B 1 585 ? 44.447 34.519 64.533 1.00 5.91 ? 585 LEU B O 1 ATOM 9442 C CB . LEU B 1 585 ? 44.636 35.371 61.917 1.00 3.88 ? 585 LEU B CB 1 ATOM 9443 C CG . LEU B 1 585 ? 43.145 35.670 62.187 1.00 2.00 ? 585 LEU B CG 1 ATOM 9444 C CD1 . LEU B 1 585 ? 42.922 37.156 62.103 1.00 2.00 ? 585 LEU B CD1 1 ATOM 9445 C CD2 . LEU B 1 585 ? 42.228 34.964 61.217 1.00 2.02 ? 585 LEU B CD2 1 ATOM 9446 N N . ASP B 1 586 ? 45.097 36.536 65.316 1.00 6.84 ? 586 ASP B N 1 ATOM 9447 C CA . ASP B 1 586 ? 44.658 36.297 66.672 1.00 5.56 ? 586 ASP B CA 1 ATOM 9448 C C . ASP B 1 586 ? 43.162 36.470 66.755 1.00 4.12 ? 586 ASP B C 1 ATOM 9449 O O . ASP B 1 586 ? 42.681 37.591 66.685 1.00 3.81 ? 586 ASP B O 1 ATOM 9450 C CB . ASP B 1 586 ? 45.315 37.304 67.602 1.00 8.62 ? 586 ASP B CB 1 ATOM 9451 C CG . ASP B 1 586 ? 44.931 37.087 69.036 1.00 11.64 ? 586 ASP B CG 1 ATOM 9452 O OD1 . ASP B 1 586 ? 43.913 36.398 69.271 1.00 13.62 ? 586 ASP B OD1 1 ATOM 9453 O OD2 . ASP B 1 586 ? 45.640 37.606 69.925 1.00 13.65 ? 586 ASP B OD2 1 ATOM 9454 N N . LEU B 1 587 ? 42.416 35.384 66.914 1.00 2.42 ? 587 LEU B N 1 ATOM 9455 C CA . LEU B 1 587 ? 40.968 35.527 67.005 1.00 3.22 ? 587 LEU B CA 1 ATOM 9456 C C . LEU B 1 587 ? 40.502 35.927 68.410 1.00 2.51 ? 587 LEU B C 1 ATOM 9457 O O . LEU B 1 587 ? 39.307 35.878 68.705 1.00 2.18 ? 587 LEU B O 1 ATOM 9458 C CB . LEU B 1 587 ? 40.253 34.234 66.581 1.00 3.35 ? 587 LEU B CB 1 ATOM 9459 C CG . LEU B 1 587 ? 40.198 33.750 65.124 1.00 4.25 ? 587 LEU B CG 1 ATOM 9460 C CD1 . LEU B 1 587 ? 39.298 32.523 65.106 1.00 6.18 ? 587 LEU B CD1 1 ATOM 9461 C CD2 . LEU B 1 587 ? 39.646 34.805 64.158 1.00 3.21 ? 587 LEU B CD2 1 ATOM 9462 N N . SER B 1 588 ? 41.427 36.340 69.272 1.00 2.00 ? 588 SER B N 1 ATOM 9463 C CA . SER B 1 588 ? 41.045 36.725 70.629 1.00 3.16 ? 588 SER B CA 1 ATOM 9464 C C . SER B 1 588 ? 39.978 37.836 70.676 1.00 3.46 ? 588 SER B C 1 ATOM 9465 O O . SER B 1 588 ? 38.941 37.679 71.327 1.00 4.74 ? 588 SER B O 1 ATOM 9466 C CB . SER B 1 588 ? 42.283 37.124 71.467 1.00 2.95 ? 588 SER B CB 1 ATOM 9467 O OG . SER B 1 588 ? 42.782 38.418 71.163 1.00 3.64 ? 588 SER B OG 1 ATOM 9468 N N . PRO B 1 589 ? 40.209 38.966 69.987 1.00 2.43 ? 589 PRO B N 1 ATOM 9469 C CA . PRO B 1 589 ? 39.201 40.023 70.029 1.00 2.79 ? 589 PRO B CA 1 ATOM 9470 C C . PRO B 1 589 ? 37.773 39.564 69.752 1.00 3.15 ? 589 PRO B C 1 ATOM 9471 O O . PRO B 1 589 ? 36.822 40.222 70.152 1.00 4.28 ? 589 PRO B O 1 ATOM 9472 C CB . PRO B 1 589 ? 39.706 41.011 68.987 1.00 2.00 ? 589 PRO B CB 1 ATOM 9473 C CG . PRO B 1 589 ? 41.177 40.916 69.166 1.00 2.00 ? 589 PRO B CG 1 ATOM 9474 C CD . PRO B 1 589 ? 41.382 39.416 69.220 1.00 3.16 ? 589 PRO B CD 1 ATOM 9475 N N . TRP B 1 590 ? 37.604 38.441 69.072 1.00 4.25 ? 590 TRP B N 1 ATOM 9476 C CA . TRP B 1 590 ? 36.250 37.982 68.788 1.00 5.26 ? 590 TRP B CA 1 ATOM 9477 C C . TRP B 1 590 ? 35.553 37.457 70.034 1.00 7.71 ? 590 TRP B C 1 ATOM 9478 O O . TRP B 1 590 ? 34.352 37.189 70.013 1.00 6.32 ? 590 TRP B O 1 ATOM 9479 C CB . TRP B 1 590 ? 36.270 36.924 67.680 1.00 4.29 ? 590 TRP B CB 1 ATOM 9480 C CG . TRP B 1 590 ? 36.217 37.546 66.323 1.00 2.74 ? 590 TRP B CG 1 ATOM 9481 C CD1 . TRP B 1 590 ? 35.104 37.741 65.560 1.00 2.70 ? 590 TRP B CD1 1 ATOM 9482 C CD2 . TRP B 1 590 ? 37.299 38.167 65.621 1.00 2.00 ? 590 TRP B CD2 1 ATOM 9483 N NE1 . TRP B 1 590 ? 35.422 38.454 64.430 1.00 3.01 ? 590 TRP B NE1 1 ATOM 9484 C CE2 . TRP B 1 590 ? 36.764 38.730 64.443 1.00 2.10 ? 590 TRP B CE2 1 ATOM 9485 C CE3 . TRP B 1 590 ? 38.668 38.310 65.876 1.00 2.00 ? 590 TRP B CE3 1 ATOM 9486 C CZ2 . TRP B 1 590 ? 37.551 39.425 63.518 1.00 2.00 ? 590 TRP B CZ2 1 ATOM 9487 C CZ3 . TRP B 1 590 ? 39.451 39.003 64.956 1.00 2.25 ? 590 TRP B CZ3 1 ATOM 9488 C CH2 . TRP B 1 590 ? 38.888 39.551 63.791 1.00 2.47 ? 590 TRP B CH2 1 ATOM 9489 N N . ALA B 1 591 ? 36.312 37.327 71.120 1.00 11.86 ? 591 ALA B N 1 ATOM 9490 C CA . ALA B 1 591 ? 35.777 36.850 72.394 1.00 16.72 ? 591 ALA B CA 1 ATOM 9491 C C . ALA B 1 591 ? 34.624 37.741 72.858 1.00 20.90 ? 591 ALA B C 1 ATOM 9492 O O . ALA B 1 591 ? 34.713 38.968 72.781 1.00 22.31 ? 591 ALA B O 1 ATOM 9493 C CB . ALA B 1 591 ? 36.879 36.847 73.450 1.00 14.07 ? 591 ALA B CB 1 ATOM 9494 N N . SER B 1 592 ? 33.539 37.134 73.331 1.00 25.34 ? 592 SER B N 1 ATOM 9495 C CA . SER B 1 592 ? 32.410 37.923 73.811 1.00 30.20 ? 592 SER B CA 1 ATOM 9496 C C . SER B 1 592 ? 32.192 37.626 75.280 1.00 34.24 ? 592 SER B C 1 ATOM 9497 O O . SER B 1 592 ? 31.956 36.479 75.667 1.00 34.32 ? 592 SER B O 1 ATOM 9498 C CB . SER B 1 592 ? 31.134 37.615 73.027 1.00 30.71 ? 592 SER B CB 1 ATOM 9499 O OG . SER B 1 592 ? 30.122 38.560 73.343 1.00 31.32 ? 592 SER B OG 1 ATOM 9500 N N . ARG B 1 593 ? 32.269 38.677 76.091 1.00 39.34 ? 593 ARG B N 1 ATOM 9501 C CA . ARG B 1 593 ? 32.115 38.571 77.536 1.00 43.43 ? 593 ARG B CA 1 ATOM 9502 C C . ARG B 1 593 ? 30.665 38.845 77.954 1.00 45.33 ? 593 ARG B C 1 ATOM 9503 O O . ARG B 1 593 ? 30.049 39.821 77.517 1.00 45.63 ? 593 ARG B O 1 ATOM 9504 C CB . ARG B 1 593 ? 33.102 39.545 78.196 1.00 45.49 ? 593 ARG B CB 1 ATOM 9505 C CG . ARG B 1 593 ? 34.339 39.793 77.304 1.00 48.75 ? 593 ARG B CG 1 ATOM 9506 C CD . ARG B 1 593 ? 35.580 40.277 78.052 1.00 51.64 ? 593 ARG B CD 1 ATOM 9507 N NE . ARG B 1 593 ? 36.085 39.291 79.010 1.00 55.10 ? 593 ARG B NE 1 ATOM 9508 C CZ . ARG B 1 593 ? 37.197 39.439 79.731 1.00 56.21 ? 593 ARG B CZ 1 ATOM 9509 N NH1 . ARG B 1 593 ? 37.940 40.534 79.609 1.00 57.06 ? 593 ARG B NH1 1 ATOM 9510 N NH2 . ARG B 1 593 ? 37.563 38.497 80.590 1.00 56.91 ? 593 ARG B NH2 1 ATOM 9511 N N . GLU B 1 594 ? 30.127 37.964 78.793 1.00 47.01 ? 594 GLU B N 1 ATOM 9512 C CA . GLU B 1 594 ? 28.745 38.059 79.260 1.00 49.01 ? 594 GLU B CA 1 ATOM 9513 C C . GLU B 1 594 ? 28.349 39.325 80.008 1.00 50.15 ? 594 GLU B C 1 ATOM 9514 O O . GLU B 1 594 ? 27.820 40.278 79.423 1.00 48.99 ? 594 GLU B O 1 ATOM 9515 C CB . GLU B 1 594 ? 28.418 36.843 80.130 1.00 48.71 ? 594 GLU B CB 1 ATOM 9516 C CG . GLU B 1 594 ? 28.544 35.564 79.359 1.00 48.78 ? 594 GLU B CG 1 ATOM 9517 C CD . GLU B 1 594 ? 27.886 35.692 78.013 1.00 48.07 ? 594 GLU B CD 1 ATOM 9518 O OE1 . GLU B 1 594 ? 26.638 35.718 77.968 1.00 47.56 ? 594 GLU B OE1 1 ATOM 9519 O OE2 . GLU B 1 594 ? 28.620 35.795 77.008 1.00 48.03 ? 594 GLU B OE2 1 ATOM 9520 N N . ASN B 1 595 ? 28.597 39.311 81.312 1.00 51.49 ? 595 ASN B N 1 ATOM 9521 C CA . ASN B 1 595 ? 28.254 40.429 82.173 1.00 53.26 ? 595 ASN B CA 1 ATOM 9522 C C . ASN B 1 595 ? 29.356 41.497 82.192 1.00 53.58 ? 595 ASN B C 1 ATOM 9523 O O . ASN B 1 595 ? 29.083 42.616 82.684 1.00 53.60 ? 595 ASN B O 1 ATOM 9524 C CB . ASN B 1 595 ? 27.957 39.911 83.593 1.00 54.42 ? 595 ASN B CB 1 ATOM 9525 C CG . ASN B 1 595 ? 26.914 38.782 83.606 1.00 55.64 ? 595 ASN B CG 1 ATOM 9526 O OD1 . ASN B 1 595 ? 26.308 38.492 84.640 1.00 56.52 ? 595 ASN B OD1 1 ATOM 9527 N ND2 . ASN B 1 595 ? 26.715 38.137 82.458 1.00 55.51 ? 595 ASN B ND2 1 ATOM 9528 O OXT . ASN B 1 595 ? 30.476 41.207 81.709 1.00 52.74 ? 595 ASN B OXT 1 HETATM 9529 C C1 . NAG C 2 . ? -15.805 -14.886 -4.151 1.00 40.59 ? 596 NAG A C1 1 HETATM 9530 C C2 . NAG C 2 . ? -17.084 -15.595 -4.677 1.00 44.92 ? 596 NAG A C2 1 HETATM 9531 C C3 . NAG C 2 . ? -17.339 -14.953 -6.029 1.00 48.28 ? 596 NAG A C3 1 HETATM 9532 C C4 . NAG C 2 . ? -17.845 -13.568 -5.668 1.00 49.98 ? 596 NAG A C4 1 HETATM 9533 C C5 . NAG C 2 . ? -16.614 -12.825 -5.227 1.00 46.86 ? 596 NAG A C5 1 HETATM 9534 C C6 . NAG C 2 . ? -16.916 -11.387 -4.946 1.00 47.41 ? 596 NAG A C6 1 HETATM 9535 C C7 . NAG C 2 . ? -18.271 -17.594 -5.071 1.00 58.06 ? 596 NAG A C7 1 HETATM 9536 C C8 . NAG C 2 . ? -18.377 -19.115 -5.288 1.00 58.85 ? 596 NAG A C8 1 HETATM 9537 N N2 . NAG C 2 . ? -17.086 -17.044 -4.778 1.00 53.01 ? 596 NAG A N2 1 HETATM 9538 O O3 . NAG C 2 . ? -18.272 -15.692 -6.846 1.00 48.31 ? 596 NAG A O3 1 HETATM 9539 O O4 . NAG C 2 . ? -18.359 -12.945 -6.848 1.00 54.25 ? 596 NAG A O4 1 HETATM 9540 O O5 . NAG C 2 . ? -16.071 -13.460 -4.023 1.00 42.48 ? 596 NAG A O5 1 HETATM 9541 O O6 . NAG C 2 . ? -17.431 -11.188 -3.658 1.00 48.77 ? 596 NAG A O6 1 HETATM 9542 O O7 . NAG C 2 . ? -19.302 -16.905 -5.134 1.00 60.80 ? 596 NAG A O7 1 HETATM 9543 C C1 . NAG D 2 . ? -19.740 -12.913 -7.050 1.00 61.04 ? 597 NAG A C1 1 HETATM 9544 C C2 . NAG D 2 . ? -19.942 -12.488 -8.500 1.00 63.24 ? 597 NAG A C2 1 HETATM 9545 C C3 . NAG D 2 . ? -21.491 -12.507 -8.810 1.00 64.95 ? 597 NAG A C3 1 HETATM 9546 C C4 . NAG D 2 . ? -22.299 -13.366 -7.880 1.00 66.07 ? 597 NAG A C4 1 HETATM 9547 C C5 . NAG D 2 . ? -21.576 -14.342 -6.910 1.00 66.97 ? 597 NAG A C5 1 HETATM 9548 C C6 . NAG D 2 . ? -21.825 -15.851 -7.099 1.00 69.21 ? 597 NAG A C6 1 HETATM 9549 C C7 . NAG D 2 . ? -17.987 -11.202 -8.981 1.00 67.21 ? 597 NAG A C7 1 HETATM 9550 C C8 . NAG D 2 . ? -17.308 -9.849 -9.254 1.00 67.85 ? 597 NAG A C8 1 HETATM 9551 N N2 . NAG D 2 . ? -19.288 -11.236 -8.731 1.00 65.42 ? 597 NAG A N2 1 HETATM 9552 O O3 . NAG D 2 . ? -21.709 -13.018 -10.106 1.00 65.19 ? 597 NAG A O3 1 HETATM 9553 O O4 . NAG D 2 . ? -23.130 -12.521 -7.087 1.00 66.87 ? 597 NAG A O4 1 HETATM 9554 O O5 . NAG D 2 . ? -20.187 -14.247 -6.967 1.00 62.91 ? 597 NAG A O5 1 HETATM 9555 O O6 . NAG D 2 . ? -21.997 -16.456 -5.822 1.00 73.71 ? 597 NAG A O6 1 HETATM 9556 O O7 . NAG D 2 . ? -17.321 -12.227 -9.054 1.00 68.94 ? 597 NAG A O7 1 HETATM 9557 C C1 . NAG E 2 . ? 19.793 -0.344 -23.300 1.00 35.16 ? 598 NAG A C1 1 HETATM 9558 C C2 . NAG E 2 . ? 20.340 -1.670 -22.757 1.00 37.96 ? 598 NAG A C2 1 HETATM 9559 C C3 . NAG E 2 . ? 21.225 -2.390 -23.792 1.00 40.80 ? 598 NAG A C3 1 HETATM 9560 C C4 . NAG E 2 . ? 20.468 -2.561 -25.117 1.00 43.76 ? 598 NAG A C4 1 HETATM 9561 C C5 . NAG E 2 . ? 19.955 -1.184 -25.559 1.00 40.40 ? 598 NAG A C5 1 HETATM 9562 C C6 . NAG E 2 . ? 19.146 -1.202 -26.837 1.00 39.14 ? 598 NAG A C6 1 HETATM 9563 C C7 . NAG E 2 . ? 20.371 -1.355 -20.357 1.00 37.79 ? 598 NAG A C7 1 HETATM 9564 C C8 . NAG E 2 . ? 21.148 -1.123 -19.073 1.00 37.53 ? 598 NAG A C8 1 HETATM 9565 N N2 . NAG E 2 . ? 21.050 -1.445 -21.505 1.00 38.54 ? 598 NAG A N2 1 HETATM 9566 O O3 . NAG E 2 . ? 21.584 -3.672 -23.287 1.00 44.33 ? 598 NAG A O3 1 HETATM 9567 O O4 . NAG E 2 . ? 21.389 -3.088 -26.113 1.00 52.75 ? 598 NAG A O4 1 HETATM 9568 O O5 . NAG E 2 . ? 19.105 -0.600 -24.538 1.00 36.51 ? 598 NAG A O5 1 HETATM 9569 O O6 . NAG E 2 . ? 18.605 -2.487 -27.088 1.00 37.88 ? 598 NAG A O6 1 HETATM 9570 O O7 . NAG E 2 . ? 19.142 -1.457 -20.303 1.00 38.04 ? 598 NAG A O7 1 HETATM 9571 C C1 . NAG F 2 . ? 21.220 -4.378 -26.622 1.00 61.13 ? 599 NAG A C1 1 HETATM 9572 C C2 . NAG F 2 . ? 22.427 -4.737 -27.518 1.00 64.51 ? 599 NAG A C2 1 HETATM 9573 C C3 . NAG F 2 . ? 22.456 -6.241 -27.900 1.00 66.28 ? 599 NAG A C3 1 HETATM 9574 C C4 . NAG F 2 . ? 22.198 -7.139 -26.683 1.00 66.57 ? 599 NAG A C4 1 HETATM 9575 C C5 . NAG F 2 . ? 20.944 -6.653 -25.952 1.00 65.70 ? 599 NAG A C5 1 HETATM 9576 C C6 . NAG F 2 . ? 20.586 -7.464 -24.719 1.00 67.67 ? 599 NAG A C6 1 HETATM 9577 C C7 . NAG F 2 . ? 22.975 -2.718 -28.729 1.00 69.46 ? 599 NAG A C7 1 HETATM 9578 C C8 . NAG F 2 . ? 22.899 -1.906 -30.019 1.00 70.34 ? 599 NAG A C8 1 HETATM 9579 N N2 . NAG F 2 . ? 22.389 -3.915 -28.714 1.00 67.39 ? 599 NAG A N2 1 HETATM 9580 O O3 . NAG F 2 . ? 23.734 -6.555 -28.448 1.00 69.23 ? 599 NAG A O3 1 HETATM 9581 O O4 . NAG F 2 . ? 22.041 -8.495 -27.100 1.00 66.23 ? 599 NAG A O4 1 HETATM 9582 O O5 . NAG F 2 . ? 21.141 -5.294 -25.520 1.00 61.88 ? 599 NAG A O5 1 HETATM 9583 O O6 . NAG F 2 . ? 21.668 -7.535 -23.804 1.00 72.09 ? 599 NAG A O6 1 HETATM 9584 O O7 . NAG F 2 . ? 23.585 -2.260 -27.760 1.00 70.49 ? 599 NAG A O7 1 HETATM 9585 C C1 . NAG G 2 . ? 22.934 -17.314 2.427 1.00 31.83 ? 600 NAG A C1 1 HETATM 9586 C C2 . NAG G 2 . ? 22.155 -18.446 3.076 1.00 35.11 ? 600 NAG A C2 1 HETATM 9587 C C3 . NAG G 2 . ? 22.571 -19.765 2.409 1.00 37.74 ? 600 NAG A C3 1 HETATM 9588 C C4 . NAG G 2 . ? 22.497 -19.696 0.872 1.00 40.26 ? 600 NAG A C4 1 HETATM 9589 C C5 . NAG G 2 . ? 23.093 -18.391 0.309 1.00 37.34 ? 600 NAG A C5 1 HETATM 9590 C C6 . NAG G 2 . ? 22.685 -18.172 -1.132 1.00 36.55 ? 600 NAG A C6 1 HETATM 9591 C C7 . NAG G 2 . ? 21.498 -18.043 5.375 1.00 38.60 ? 600 NAG A C7 1 HETATM 9592 C C8 . NAG G 2 . ? 21.846 -18.097 6.855 1.00 39.65 ? 600 NAG A C8 1 HETATM 9593 N N2 . NAG G 2 . ? 22.420 -18.469 4.509 1.00 37.34 ? 600 NAG A N2 1 HETATM 9594 O O3 . NAG G 2 . ? 21.701 -20.786 2.858 1.00 39.62 ? 600 NAG A O3 1 HETATM 9595 O O4 . NAG G 2 . ? 23.218 -20.816 0.310 1.00 49.06 ? 600 NAG A O4 1 HETATM 9596 O O5 . NAG G 2 . ? 22.614 -17.243 1.039 1.00 32.38 ? 600 NAG A O5 1 HETATM 9597 O O6 . NAG G 2 . ? 23.410 -17.104 -1.710 1.00 38.31 ? 600 NAG A O6 1 HETATM 9598 O O7 . NAG G 2 . ? 20.392 -17.617 5.026 1.00 39.74 ? 600 NAG A O7 1 HETATM 9599 C C1 . NAG H 2 . ? 22.571 -21.597 -0.634 1.00 57.39 ? 601 NAG A C1 1 HETATM 9600 C C2 . NAG H 2 . ? 23.531 -21.942 -1.783 1.00 62.44 ? 601 NAG A C2 1 HETATM 9601 C C3 . NAG H 2 . ? 23.003 -23.186 -2.530 1.00 64.96 ? 601 NAG A C3 1 HETATM 9602 C C4 . NAG H 2 . ? 22.951 -24.411 -1.593 1.00 66.79 ? 601 NAG A C4 1 HETATM 9603 C C5 . NAG H 2 . ? 22.909 -23.979 -0.128 1.00 65.00 ? 601 NAG A C5 1 HETATM 9604 C C6 . NAG H 2 . ? 24.270 -23.719 0.500 1.00 64.65 ? 601 NAG A C6 1 HETATM 9605 C C7 . NAG H 2 . ? 24.820 -20.220 -2.888 1.00 68.15 ? 601 NAG A C7 1 HETATM 9606 C C8 . NAG H 2 . ? 24.858 -19.017 -3.825 1.00 68.72 ? 601 NAG A C8 1 HETATM 9607 N N2 . NAG H 2 . ? 23.639 -20.799 -2.675 1.00 65.74 ? 601 NAG A N2 1 HETATM 9608 O O3 . NAG H 2 . ? 23.855 -23.472 -3.627 1.00 66.65 ? 601 NAG A O3 1 HETATM 9609 O O4 . NAG H 2 . ? 21.776 -25.206 -1.888 1.00 72.21 ? 601 NAG A O4 1 HETATM 9610 O O5 . NAG H 2 . ? 22.078 -22.788 0.036 1.00 59.95 ? 601 NAG A O5 1 HETATM 9611 O O6 . NAG H 2 . ? 24.206 -23.862 1.909 1.00 67.48 ? 601 NAG A O6 1 HETATM 9612 O O7 . NAG H 2 . ? 25.869 -20.628 -2.368 1.00 69.41 ? 601 NAG A O7 1 HETATM 9613 C C1 . MAN I 3 . ? 21.865 -26.606 -1.867 1.00 77.48 ? 602 MAN A C1 1 HETATM 9614 C C2 . MAN I 3 . ? 22.406 -27.130 -0.517 1.00 79.08 ? 602 MAN A C2 1 HETATM 9615 C C3 . MAN I 3 . ? 23.181 -28.432 -0.730 1.00 80.56 ? 602 MAN A C3 1 HETATM 9616 C C4 . MAN I 3 . ? 22.545 -29.243 -1.859 1.00 80.40 ? 602 MAN A C4 1 HETATM 9617 C C5 . MAN I 3 . ? 22.657 -28.476 -3.182 1.00 80.45 ? 602 MAN A C5 1 HETATM 9618 C C6 . MAN I 3 . ? 21.469 -28.709 -4.100 1.00 79.70 ? 602 MAN A C6 1 HETATM 9619 O O2 . MAN I 3 . ? 21.314 -27.378 0.356 1.00 80.31 ? 602 MAN A O2 1 HETATM 9620 O O3 . MAN I 3 . ? 23.204 -29.186 0.477 1.00 80.82 ? 602 MAN A O3 1 HETATM 9621 O O4 . MAN I 3 . ? 23.172 -30.515 -1.962 1.00 82.17 ? 602 MAN A O4 1 HETATM 9622 O O5 . MAN I 3 . ? 22.717 -27.039 -2.949 1.00 79.10 ? 602 MAN A O5 1 HETATM 9623 O O6 . MAN I 3 . ? 21.759 -28.316 -5.431 1.00 78.70 ? 602 MAN A O6 1 HETATM 9624 C C1 . NAG J 2 . ? -18.425 18.442 -8.620 1.00 44.56 ? 603 NAG A C1 1 HETATM 9625 C C2 . NAG J 2 . ? -19.863 17.912 -8.493 1.00 49.42 ? 603 NAG A C2 1 HETATM 9626 C C3 . NAG J 2 . ? -20.568 18.258 -7.165 1.00 52.82 ? 603 NAG A C3 1 HETATM 9627 C C4 . NAG J 2 . ? -19.871 19.281 -6.206 1.00 53.21 ? 603 NAG A C4 1 HETATM 9628 C C5 . NAG J 2 . ? -18.423 19.674 -6.594 1.00 51.41 ? 603 NAG A C5 1 HETATM 9629 C C6 . NAG J 2 . ? -17.508 19.933 -5.395 1.00 50.89 ? 603 NAG A C6 1 HETATM 9630 C C7 . NAG J 2 . ? -21.399 17.485 -10.329 1.00 60.07 ? 603 NAG A C7 1 HETATM 9631 C C8 . NAG J 2 . ? -22.229 18.042 -11.477 1.00 61.93 ? 603 NAG A C8 1 HETATM 9632 N N2 . NAG J 2 . ? -20.684 18.358 -9.608 1.00 56.50 ? 603 NAG A N2 1 HETATM 9633 O O3 . NAG J 2 . ? -20.788 17.045 -6.466 1.00 57.33 ? 603 NAG A O3 1 HETATM 9634 O O4 . NAG J 2 . ? -20.673 20.455 -6.066 1.00 54.51 ? 603 NAG A O4 1 HETATM 9635 O O5 . NAG J 2 . ? -17.810 18.620 -7.342 1.00 45.87 ? 603 NAG A O5 1 HETATM 9636 O O6 . NAG J 2 . ? -17.493 18.830 -4.501 1.00 53.06 ? 603 NAG A O6 1 HETATM 9637 O O7 . NAG J 2 . ? -21.417 16.269 -10.103 1.00 61.30 ? 603 NAG A O7 1 HETATM 9638 CA CA . CA K 4 . ? 0.995 8.313 -8.027 1.00 2.00 ? 1001 CA A CA 1 HETATM 9639 C C . CO3 L 5 . ? -17.241 -13.136 -0.625 1.00 26.29 ? 2001 CO3 A C 1 HETATM 9640 O O1 . CO3 L 5 . ? -17.008 -12.369 0.401 1.00 26.18 ? 2001 CO3 A O1 1 HETATM 9641 O O2 . CO3 L 5 . ? -16.728 -14.335 -0.678 1.00 27.38 ? 2001 CO3 A O2 1 HETATM 9642 O O3 . CO3 L 5 . ? -17.989 -12.711 -1.598 1.00 24.80 ? 2001 CO3 A O3 1 HETATM 9643 C CHA . HEM M 6 . ? 3.036 1.239 5.893 1.00 3.22 ? 605 HEM A CHA 1 HETATM 9644 C CHB . HEM M 6 . ? 5.371 -2.907 6.160 1.00 2.15 ? 605 HEM A CHB 1 HETATM 9645 C CHC . HEM M 6 . ? 1.582 -4.635 3.354 1.00 2.00 ? 605 HEM A CHC 1 HETATM 9646 C CHD . HEM M 6 . ? -0.846 -0.392 3.294 1.00 2.27 ? 605 HEM A CHD 1 HETATM 9647 C C1A . HEM M 6 . ? 3.987 0.300 6.236 1.00 2.00 ? 605 HEM A C1A 1 HETATM 9648 C C2A . HEM M 6 . ? 5.118 0.562 7.050 1.00 2.00 ? 605 HEM A C2A 1 HETATM 9649 C C3A . HEM M 6 . ? 5.841 -0.549 7.179 1.00 2.00 ? 605 HEM A C3A 1 HETATM 9650 C C4A . HEM M 6 . ? 5.127 -1.564 6.414 1.00 2.00 ? 605 HEM A C4A 1 HETATM 9651 C CMA . HEM M 6 . ? 7.150 -0.626 8.000 1.00 3.54 ? 605 HEM A CMA 1 HETATM 9652 C CAA . HEM M 6 . ? 5.415 1.947 7.663 1.00 2.33 ? 605 HEM A CAA 1 HETATM 9653 C CBA . HEM M 6 . ? 4.536 1.996 8.919 1.00 2.69 ? 605 HEM A CBA 1 HETATM 9654 C CGA . HEM M 6 . ? 4.676 3.325 9.694 1.00 3.33 ? 605 HEM A CGA 1 HETATM 9655 O O1A . HEM M 6 . ? 5.844 3.811 9.963 1.00 4.22 ? 605 HEM A O1A 1 HETATM 9656 O O2A . HEM M 6 . ? 3.566 3.835 10.004 1.00 2.73 ? 605 HEM A O2A 1 HETATM 9657 C C1B . HEM M 6 . ? 4.528 -3.747 5.360 1.00 3.03 ? 605 HEM A C1B 1 HETATM 9658 C C2B . HEM M 6 . ? 4.785 -5.119 4.999 1.00 2.94 ? 605 HEM A C2B 1 HETATM 9659 C C3B . HEM M 6 . ? 3.769 -5.568 4.238 1.00 3.24 ? 605 HEM A C3B 1 HETATM 9660 C C4B . HEM M 6 . ? 2.779 -4.534 4.069 1.00 2.92 ? 605 HEM A C4B 1 HETATM 9661 C CMB . HEM M 6 . ? 5.984 -6.014 5.372 1.00 2.00 ? 605 HEM A CMB 1 HETATM 9662 C CAB . HEM M 6 . ? 3.753 -7.019 3.689 1.00 4.31 ? 605 HEM A CAB 1 HETATM 9663 C CBB . HEM M 6 . ? 3.393 -7.960 4.609 1.00 4.81 ? 605 HEM A CBB 1 HETATM 9664 C C1C . HEM M 6 . ? 0.560 -3.678 3.101 1.00 2.66 ? 605 HEM A C1C 1 HETATM 9665 C C2C . HEM M 6 . ? -0.718 -3.838 2.335 1.00 3.14 ? 605 HEM A C2C 1 HETATM 9666 C C3C . HEM M 6 . ? -1.400 -2.619 2.320 1.00 2.01 ? 605 HEM A C3C 1 HETATM 9667 C C4C . HEM M 6 . ? -0.556 -1.720 3.076 1.00 2.00 ? 605 HEM A C4C 1 HETATM 9668 C CMC . HEM M 6 . ? -1.224 -5.161 1.648 1.00 3.41 ? 605 HEM A CMC 1 HETATM 9669 C CAC . HEM M 6 . ? -2.762 -2.185 1.685 1.00 2.00 ? 605 HEM A CAC 1 HETATM 9670 C CBC . HEM M 6 . ? -3.733 -3.085 1.487 1.00 2.00 ? 605 HEM A CBC 1 HETATM 9671 C C1D . HEM M 6 . ? 0.052 0.427 3.990 1.00 3.57 ? 605 HEM A C1D 1 HETATM 9672 C C2D . HEM M 6 . ? -0.161 1.838 4.089 1.00 3.72 ? 605 HEM A C2D 1 HETATM 9673 C C3D . HEM M 6 . ? 1.036 2.392 4.871 1.00 3.46 ? 605 HEM A C3D 1 HETATM 9674 C C4D . HEM M 6 . ? 1.846 1.199 5.174 1.00 3.63 ? 605 HEM A C4D 1 HETATM 9675 C CMD . HEM M 6 . ? -1.345 2.517 3.513 1.00 2.00 ? 605 HEM A CMD 1 HETATM 9676 C CAD . HEM M 6 . ? 1.312 3.890 5.226 1.00 4.54 ? 605 HEM A CAD 1 HETATM 9677 C CBD . HEM M 6 . ? 1.647 4.751 3.996 1.00 4.69 ? 605 HEM A CBD 1 HETATM 9678 C CGD . HEM M 6 . ? 1.886 6.103 4.556 1.00 5.47 ? 605 HEM A CGD 1 HETATM 9679 O O1D . HEM M 6 . ? 0.929 6.814 4.858 1.00 6.95 ? 605 HEM A O1D 1 HETATM 9680 O O2D . HEM M 6 . ? 3.040 6.532 4.705 1.00 6.19 ? 605 HEM A O2D 1 HETATM 9681 N NA . HEM M 6 . ? 4.021 -0.981 5.870 1.00 2.00 ? 605 HEM A NA 1 HETATM 9682 N NB . HEM M 6 . ? 3.289 -3.444 4.757 1.00 4.21 ? 605 HEM A NB 1 HETATM 9683 N NC . HEM M 6 . ? 0.622 -2.358 3.525 1.00 3.18 ? 605 HEM A NC 1 HETATM 9684 N ND . HEM M 6 . ? 1.239 0.077 4.640 1.00 3.23 ? 605 HEM A ND 1 HETATM 9685 FE FE . HEM M 6 . ? 2.169 -1.678 4.860 1.00 7.82 ? 605 HEM A FE 1 HETATM 9686 C C . FMT N 7 . ? 3.692 -23.101 -16.455 1.00 45.95 ? 3001 FMT A C 1 HETATM 9687 O O1 . FMT N 7 . ? 3.438 -23.860 -17.365 1.00 46.41 ? 3001 FMT A O1 1 HETATM 9688 O O2 . FMT N 7 . ? 2.755 -22.790 -15.544 1.00 45.50 ? 3001 FMT A O2 1 HETATM 9689 C C . FMT O 7 . ? -6.673 13.922 8.271 1.00 19.66 ? 3002 FMT A C 1 HETATM 9690 O O1 . FMT O 7 . ? -7.368 13.663 7.320 1.00 18.10 ? 3002 FMT A O1 1 HETATM 9691 O O2 . FMT O 7 . ? -7.209 14.487 9.367 1.00 21.54 ? 3002 FMT A O2 1 HETATM 9692 C C . FMT P 7 . ? 6.234 -0.742 3.283 1.00 19.81 ? 3003 FMT A C 1 HETATM 9693 O O1 . FMT P 7 . ? 7.221 -0.027 3.195 1.00 20.77 ? 3003 FMT A O1 1 HETATM 9694 O O2 . FMT P 7 . ? 5.007 -0.307 2.876 1.00 17.34 ? 3003 FMT A O2 1 HETATM 9695 C C1 . NAG Q 2 . ? 59.444 41.589 42.332 1.00 41.12 ? 596 NAG B C1 1 HETATM 9696 C C2 . NAG Q 2 . ? 60.481 42.718 42.280 1.00 44.78 ? 596 NAG B C2 1 HETATM 9697 C C3 . NAG Q 2 . ? 60.592 43.433 43.648 1.00 49.98 ? 596 NAG B C3 1 HETATM 9698 C C4 . NAG Q 2 . ? 59.220 43.817 44.211 1.00 52.19 ? 596 NAG B C4 1 HETATM 9699 C C5 . NAG Q 2 . ? 58.315 42.585 44.198 1.00 49.90 ? 596 NAG B C5 1 HETATM 9700 C C6 . NAG Q 2 . ? 56.901 42.856 44.704 1.00 50.77 ? 596 NAG B C6 1 HETATM 9701 C C7 . NAG Q 2 . ? 62.494 42.719 40.934 1.00 51.03 ? 596 NAG B C7 1 HETATM 9702 C C8 . NAG Q 2 . ? 63.821 42.049 40.605 1.00 51.14 ? 596 NAG B C8 1 HETATM 9703 N N2 . NAG Q 2 . ? 61.765 42.155 41.895 1.00 48.90 ? 596 NAG B N2 1 HETATM 9704 O O3 . NAG Q 2 . ? 61.362 44.614 43.503 1.00 51.33 ? 596 NAG B O3 1 HETATM 9705 O O4 . NAG Q 2 . ? 59.380 44.294 45.566 1.00 59.26 ? 596 NAG B O4 1 HETATM 9706 O O5 . NAG Q 2 . ? 58.198 42.083 42.846 1.00 44.14 ? 596 NAG B O5 1 HETATM 9707 O O6 . NAG Q 2 . ? 56.457 44.159 44.348 1.00 52.79 ? 596 NAG B O6 1 HETATM 9708 O O7 . NAG Q 2 . ? 62.148 43.739 40.326 1.00 52.67 ? 596 NAG B O7 1 HETATM 9709 C C1 . NAG R 2 . ? 58.644 45.402 45.967 1.00 65.68 ? 597 NAG B C1 1 HETATM 9710 C C2 . NAG R 2 . ? 58.536 45.394 47.497 1.00 68.54 ? 597 NAG B C2 1 HETATM 9711 C C3 . NAG R 2 . ? 58.205 46.767 48.135 1.00 70.18 ? 597 NAG B C3 1 HETATM 9712 C C4 . NAG R 2 . ? 58.356 48.022 47.241 1.00 70.62 ? 597 NAG B C4 1 HETATM 9713 C C5 . NAG R 2 . ? 58.562 47.763 45.745 1.00 70.31 ? 597 NAG B C5 1 HETATM 9714 C C6 . NAG R 2 . ? 59.320 48.913 45.098 1.00 70.58 ? 597 NAG B C6 1 HETATM 9715 C C7 . NAG R 2 . ? 57.843 43.198 48.245 1.00 70.28 ? 597 NAG B C7 1 HETATM 9716 C C8 . NAG R 2 . ? 56.704 42.262 48.620 1.00 70.83 ? 597 NAG B C8 1 HETATM 9717 N N2 . NAG R 2 . ? 57.515 44.438 47.887 1.00 69.50 ? 597 NAG B N2 1 HETATM 9718 O O3 . NAG R 2 . ? 59.034 46.943 49.274 1.00 70.99 ? 597 NAG B O3 1 HETATM 9719 O O4 . NAG R 2 . ? 57.204 48.843 47.390 1.00 71.85 ? 597 NAG B O4 1 HETATM 9720 O O5 . NAG R 2 . ? 59.341 46.572 45.534 1.00 67.37 ? 597 NAG B O5 1 HETATM 9721 O O6 . NAG R 2 . ? 59.681 48.615 43.760 1.00 72.63 ? 597 NAG B O6 1 HETATM 9722 O O7 . NAG R 2 . ? 59.007 42.798 48.297 1.00 70.25 ? 597 NAG B O7 1 HETATM 9723 C C1 . NAG S 2 . ? 29.375 17.336 60.404 1.00 28.23 ? 598 NAG B C1 1 HETATM 9724 C C2 . NAG S 2 . ? 30.126 16.285 59.578 1.00 31.35 ? 598 NAG B C2 1 HETATM 9725 C C3 . NAG S 2 . ? 30.412 15.014 60.393 1.00 36.45 ? 598 NAG B C3 1 HETATM 9726 C C4 . NAG S 2 . ? 31.066 15.341 61.735 1.00 39.17 ? 598 NAG B C4 1 HETATM 9727 C C5 . NAG S 2 . ? 30.235 16.402 62.467 1.00 37.51 ? 598 NAG B C5 1 HETATM 9728 C C6 . NAG S 2 . ? 30.902 16.856 63.763 1.00 37.10 ? 598 NAG B C6 1 HETATM 9729 C C7 . NAG S 2 . ? 29.488 16.700 57.281 1.00 34.08 ? 598 NAG B C7 1 HETATM 9730 C C8 . NAG S 2 . ? 28.649 16.334 56.064 1.00 34.19 ? 598 NAG B C8 1 HETATM 9731 N N2 . NAG S 2 . ? 29.350 15.966 58.389 1.00 34.13 ? 598 NAG B N2 1 HETATM 9732 O O3 . NAG S 2 . ? 31.284 14.186 59.646 1.00 34.92 ? 598 NAG B O3 1 HETATM 9733 O O4 . NAG S 2 . ? 31.185 14.136 62.544 1.00 45.97 ? 598 NAG B O4 1 HETATM 9734 O O5 . NAG S 2 . ? 30.071 17.582 61.640 1.00 30.96 ? 598 NAG B O5 1 HETATM 9735 O O6 . NAG S 2 . ? 32.320 16.792 63.668 1.00 40.71 ? 598 NAG B O6 1 HETATM 9736 O O7 . NAG S 2 . ? 30.264 17.657 57.209 1.00 33.48 ? 598 NAG B O7 1 HETATM 9737 C C1 . NAG T 2 . ? 32.468 13.763 62.955 1.00 53.33 ? 599 NAG B C1 1 HETATM 9738 C C2 . NAG T 2 . ? 32.400 12.779 64.155 1.00 57.23 ? 599 NAG B C2 1 HETATM 9739 C C3 . NAG T 2 . ? 33.760 12.089 64.456 1.00 58.96 ? 599 NAG B C3 1 HETATM 9740 C C4 . NAG T 2 . ? 34.571 11.739 63.202 1.00 59.00 ? 599 NAG B C4 1 HETATM 9741 C C5 . NAG T 2 . ? 34.517 12.861 62.160 1.00 58.76 ? 599 NAG B C5 1 HETATM 9742 C C6 . NAG T 2 . ? 35.218 12.489 60.857 1.00 59.32 ? 599 NAG B C6 1 HETATM 9743 C C7 . NAG T 2 . ? 30.876 13.242 65.983 1.00 60.04 ? 599 NAG B C7 1 HETATM 9744 C C8 . NAG T 2 . ? 30.584 14.079 67.216 1.00 60.73 ? 599 NAG B C8 1 HETATM 9745 N N2 . NAG T 2 . ? 32.006 13.523 65.339 1.00 58.67 ? 599 NAG B N2 1 HETATM 9746 O O3 . NAG T 2 . ? 33.540 10.890 65.197 1.00 59.63 ? 599 NAG B O3 1 HETATM 9747 O O4 . NAG T 2 . ? 35.931 11.507 63.569 1.00 60.29 ? 599 NAG B O4 1 HETATM 9748 O O5 . NAG T 2 . ? 33.146 13.170 61.845 1.00 55.37 ? 599 NAG B O5 1 HETATM 9749 O O6 . NAG T 2 . ? 34.294 12.193 59.822 1.00 61.39 ? 599 NAG B O6 1 HETATM 9750 O O7 . NAG T 2 . ? 30.079 12.378 65.620 1.00 60.47 ? 599 NAG B O7 1 HETATM 9751 C C1 . NAG U 2 . ? 42.406 6.587 35.399 1.00 28.12 ? 600 NAG B C1 1 HETATM 9752 C C2 . NAG U 2 . ? 43.818 6.657 34.825 1.00 30.46 ? 600 NAG B C2 1 HETATM 9753 C C3 . NAG U 2 . ? 44.794 5.814 35.614 1.00 34.98 ? 600 NAG B C3 1 HETATM 9754 C C4 . NAG U 2 . ? 44.656 5.964 37.117 1.00 38.28 ? 600 NAG B C4 1 HETATM 9755 C C5 . NAG U 2 . ? 43.158 6.085 37.580 1.00 36.44 ? 600 NAG B C5 1 HETATM 9756 C C6 . NAG U 2 . ? 42.915 6.525 39.020 1.00 36.63 ? 600 NAG B C6 1 HETATM 9757 C C7 . NAG U 2 . ? 43.682 7.097 32.471 1.00 37.23 ? 600 NAG B C7 1 HETATM 9758 C C8 . NAG U 2 . ? 43.691 6.618 31.027 1.00 39.15 ? 600 NAG B C8 1 HETATM 9759 N N2 . NAG U 2 . ? 43.821 6.205 33.448 1.00 36.42 ? 600 NAG B N2 1 HETATM 9760 O O3 . NAG U 2 . ? 46.107 6.211 35.253 1.00 32.52 ? 600 NAG B O3 1 HETATM 9761 O O4 . NAG U 2 . ? 45.234 4.763 37.661 1.00 46.07 ? 600 NAG B O4 1 HETATM 9762 O O5 . NAG U 2 . ? 42.441 7.017 36.749 1.00 30.88 ? 600 NAG B O5 1 HETATM 9763 O O6 . NAG U 2 . ? 41.824 5.807 39.583 1.00 36.87 ? 600 NAG B O6 1 HETATM 9764 O O7 . NAG U 2 . ? 43.576 8.304 32.700 1.00 38.18 ? 600 NAG B O7 1 HETATM 9765 C C1 . NAG V 2 . ? 46.436 4.750 38.368 1.00 54.84 ? 601 NAG B C1 1 HETATM 9766 C C2 . NAG V 2 . ? 46.666 3.318 38.770 1.00 59.00 ? 601 NAG B C2 1 HETATM 9767 C C3 . NAG V 2 . ? 47.951 3.104 39.548 1.00 61.95 ? 601 NAG B C3 1 HETATM 9768 C C4 . NAG V 2 . ? 49.114 3.767 38.829 1.00 64.56 ? 601 NAG B C4 1 HETATM 9769 C C5 . NAG V 2 . ? 48.696 4.414 37.469 1.00 62.24 ? 601 NAG B C5 1 HETATM 9770 C C6 . NAG V 2 . ? 48.490 3.532 36.240 1.00 61.89 ? 601 NAG B C6 1 HETATM 9771 C C7 . NAG V 2 . ? 44.554 2.275 38.850 1.00 61.89 ? 601 NAG B C7 1 HETATM 9772 C C8 . NAG V 2 . ? 43.345 1.823 39.640 1.00 61.22 ? 601 NAG B C8 1 HETATM 9773 N N2 . NAG V 2 . ? 45.514 2.885 39.526 1.00 60.52 ? 601 NAG B N2 1 HETATM 9774 O O3 . NAG V 2 . ? 48.204 1.718 39.674 1.00 62.34 ? 601 NAG B O3 1 HETATM 9775 O O4 . NAG V 2 . ? 49.685 4.770 39.706 1.00 70.57 ? 601 NAG B O4 1 HETATM 9776 O O5 . NAG V 2 . ? 47.521 5.272 37.574 1.00 57.86 ? 601 NAG B O5 1 HETATM 9777 O O6 . NAG V 2 . ? 49.446 3.837 35.224 1.00 62.80 ? 601 NAG B O6 1 HETATM 9778 O O7 . NAG V 2 . ? 44.635 2.060 37.627 1.00 62.32 ? 601 NAG B O7 1 HETATM 9779 C C1 . MAN W 3 . ? 51.135 4.974 39.764 1.00 76.06 ? 602 MAN B C1 1 HETATM 9780 C C2 . MAN W 3 . ? 51.183 5.695 41.131 1.00 78.51 ? 602 MAN B C2 1 HETATM 9781 C C3 . MAN W 3 . ? 52.347 6.668 41.267 1.00 80.52 ? 602 MAN B C3 1 HETATM 9782 C C4 . MAN W 3 . ? 53.535 6.240 40.448 1.00 80.82 ? 602 MAN B C4 1 HETATM 9783 C C5 . MAN W 3 . ? 53.174 6.227 38.981 1.00 80.01 ? 602 MAN B C5 1 HETATM 9784 C C6 . MAN W 3 . ? 54.164 5.482 38.104 1.00 79.57 ? 602 MAN B C6 1 HETATM 9785 O O2 . MAN W 3 . ? 51.211 4.740 42.190 1.00 79.33 ? 602 MAN B O2 1 HETATM 9786 O O3 . MAN W 3 . ? 52.725 6.798 42.633 1.00 82.10 ? 602 MAN B O3 1 HETATM 9787 O O4 . MAN W 3 . ? 54.580 7.185 40.633 1.00 83.16 ? 602 MAN B O4 1 HETATM 9788 O O5 . MAN W 3 . ? 51.837 5.699 38.712 1.00 77.72 ? 602 MAN B O5 1 HETATM 9789 O O6 . MAN W 3 . ? 53.906 5.735 36.729 1.00 79.19 ? 602 MAN B O6 1 HETATM 9790 C C1 . NAG X 2 . ? 31.316 60.168 47.568 1.00 49.84 ? 603 NAG B C1 1 HETATM 9791 C C2 . NAG X 2 . ? 32.727 60.691 47.275 1.00 56.66 ? 603 NAG B C2 1 HETATM 9792 C C3 . NAG X 2 . ? 32.808 62.229 47.093 1.00 60.84 ? 603 NAG B C3 1 HETATM 9793 C C4 . NAG X 2 . ? 31.592 63.080 47.612 1.00 61.77 ? 603 NAG B C4 1 HETATM 9794 C C5 . NAG X 2 . ? 30.302 62.270 47.837 1.00 61.00 ? 603 NAG B C5 1 HETATM 9795 C C6 . NAG X 2 . ? 29.002 63.011 47.530 1.00 62.03 ? 603 NAG B C6 1 HETATM 9796 C C7 . NAG X 2 . ? 34.463 59.293 48.224 1.00 63.27 ? 603 NAG B C7 1 HETATM 9797 C C8 . NAG X 2 . ? 35.280 58.949 49.455 1.00 64.66 ? 603 NAG B C8 1 HETATM 9798 N N2 . NAG X 2 . ? 33.592 60.289 48.367 1.00 61.37 ? 603 NAG B N2 1 HETATM 9799 O O3 . NAG X 2 . ? 32.993 62.517 45.715 1.00 61.58 ? 603 NAG B O3 1 HETATM 9800 O O4 . NAG X 2 . ? 31.943 63.753 48.812 1.00 63.01 ? 603 NAG B O4 1 HETATM 9801 O O5 . NAG X 2 . ? 30.322 61.054 47.065 1.00 56.27 ? 603 NAG B O5 1 HETATM 9802 O O6 . NAG X 2 . ? 29.087 63.817 46.365 1.00 62.20 ? 603 NAG B O6 1 HETATM 9803 O O7 . NAG X 2 . ? 34.642 58.683 47.163 1.00 65.10 ? 603 NAG B O7 1 HETATM 9804 CA CA . CA Y 4 . ? 30.698 38.166 45.265 1.00 2.00 ? 1002 CA B CA 1 HETATM 9805 C C . CO3 Z 5 . ? 58.743 43.852 38.510 1.00 36.42 ? 2002 CO3 B C 1 HETATM 9806 O O1 . CO3 Z 5 . ? 58.875 43.166 37.409 1.00 36.73 ? 2002 CO3 B O1 1 HETATM 9807 O O2 . CO3 Z 5 . ? 57.782 43.567 39.350 1.00 36.01 ? 2002 CO3 B O2 1 HETATM 9808 O O3 . CO3 Z 5 . ? 59.568 44.823 38.775 1.00 35.44 ? 2002 CO3 B O3 1 HETATM 9809 C CHA . HEM AA 6 . ? 35.663 32.579 31.639 1.00 11.34 ? 605 HEM B CHA 1 HETATM 9810 C CHB . HEM AA 6 . ? 38.387 28.675 31.328 1.00 12.22 ? 605 HEM B CHB 1 HETATM 9811 C CHC . HEM AA 6 . ? 41.570 31.424 34.100 1.00 12.55 ? 605 HEM B CHC 1 HETATM 9812 C CHD . HEM AA 6 . ? 38.801 35.424 34.212 1.00 11.51 ? 605 HEM B CHD 1 HETATM 9813 C C1A . HEM AA 6 . ? 36.086 31.323 31.298 1.00 10.11 ? 605 HEM B C1A 1 HETATM 9814 C C2A . HEM AA 6 . ? 35.336 30.427 30.494 1.00 9.55 ? 605 HEM B C2A 1 HETATM 9815 C C3A . HEM AA 6 . ? 36.027 29.285 30.346 1.00 9.99 ? 605 HEM B C3A 1 HETATM 9816 C C4A . HEM AA 6 . ? 37.265 29.482 31.102 1.00 11.09 ? 605 HEM B C4A 1 HETATM 9817 C CMA . HEM AA 6 . ? 35.510 28.081 29.538 1.00 11.24 ? 605 HEM B CMA 1 HETATM 9818 C CAA . HEM AA 6 . ? 33.932 30.778 29.910 1.00 9.82 ? 605 HEM B CAA 1 HETATM 9819 C CBA . HEM AA 6 . ? 34.176 31.698 28.695 1.00 7.76 ? 605 HEM B CBA 1 HETATM 9820 C CGA . HEM AA 6 . ? 32.850 32.156 28.017 1.00 6.39 ? 605 HEM B CGA 1 HETATM 9821 O O1A . HEM AA 6 . ? 32.024 31.297 27.539 1.00 2.47 ? 605 HEM B O1A 1 HETATM 9822 O O2A . HEM AA 6 . ? 32.693 33.406 28.012 1.00 6.58 ? 605 HEM B O2A 1 HETATM 9823 C C1B . HEM AA 6 . ? 39.511 29.096 32.112 1.00 12.38 ? 605 HEM B C1B 1 HETATM 9824 C C2B . HEM AA 6 . ? 40.681 28.320 32.402 1.00 12.70 ? 605 HEM B C2B 1 HETATM 9825 C C3B . HEM AA 6 . ? 41.521 29.061 33.171 1.00 13.74 ? 605 HEM B C3B 1 HETATM 9826 C C4B . HEM AA 6 . ? 40.965 30.373 33.388 1.00 13.32 ? 605 HEM B C4B 1 HETATM 9827 C CMB . HEM AA 6 . ? 41.001 26.874 31.966 1.00 10.62 ? 605 HEM B CMB 1 HETATM 9828 C CAB . HEM AA 6 . ? 42.895 28.520 33.682 1.00 13.80 ? 605 HEM B CAB 1 HETATM 9829 C CBB . HEM AA 6 . ? 43.803 28.138 32.739 1.00 14.97 ? 605 HEM B CBB 1 HETATM 9830 C C1C . HEM AA 6 . ? 41.152 32.753 34.381 1.00 11.45 ? 605 HEM B C1C 1 HETATM 9831 C C2C . HEM AA 6 . ? 41.872 33.847 35.120 1.00 11.02 ? 605 HEM B C2C 1 HETATM 9832 C C3C . HEM AA 6 . ? 41.076 34.981 35.153 1.00 11.49 ? 605 HEM B C3C 1 HETATM 9833 C C4C . HEM AA 6 . ? 39.878 34.601 34.429 1.00 12.20 ? 605 HEM B C4C 1 HETATM 9834 C CMC . HEM AA 6 . ? 43.290 33.734 35.775 1.00 7.62 ? 605 HEM B CMC 1 HETATM 9835 C CAC . HEM AA 6 . ? 41.283 36.411 35.782 1.00 11.73 ? 605 HEM B CAC 1 HETATM 9836 C CBC . HEM AA 6 . ? 42.301 36.647 36.630 1.00 13.33 ? 605 HEM B CBC 1 HETATM 9837 C C1D . HEM AA 6 . ? 37.680 34.928 33.548 1.00 11.59 ? 605 HEM B C1D 1 HETATM 9838 C C2D . HEM AA 6 . ? 36.452 35.660 33.533 1.00 12.72 ? 605 HEM B C2D 1 HETATM 9839 C C3D . HEM AA 6 . ? 35.442 34.799 32.769 1.00 14.14 ? 605 HEM B C3D 1 HETATM 9840 C C4D . HEM AA 6 . ? 36.215 33.617 32.369 1.00 13.01 ? 605 HEM B C4D 1 HETATM 9841 C CMD . HEM AA 6 . ? 36.272 36.987 34.174 1.00 12.54 ? 605 HEM B CMD 1 HETATM 9842 C CAD . HEM AA 6 . ? 33.927 35.158 32.512 1.00 14.05 ? 605 HEM B CAD 1 HETATM 9843 C CBD . HEM AA 6 . ? 33.110 35.270 33.814 1.00 13.47 ? 605 HEM B CBD 1 HETATM 9844 C CGD . HEM AA 6 . ? 31.736 35.619 33.383 1.00 15.49 ? 605 HEM B CGD 1 HETATM 9845 O O1D . HEM AA 6 . ? 31.483 36.778 33.019 1.00 17.08 ? 605 HEM B O1D 1 HETATM 9846 O O2D . HEM AA 6 . ? 30.833 34.771 33.420 1.00 17.01 ? 605 HEM B O2D 1 HETATM 9847 N NA . HEM AA 6 . ? 37.234 30.738 31.642 1.00 10.63 ? 605 HEM B NA 1 HETATM 9848 N NB . HEM AA 6 . ? 39.740 30.344 32.735 1.00 13.66 ? 605 HEM B NB 1 HETATM 9849 N NC . HEM AA 6 . ? 39.937 33.273 33.972 1.00 13.14 ? 605 HEM B NC 1 HETATM 9850 N ND . HEM AA 6 . ? 37.520 33.725 32.846 1.00 12.31 ? 605 HEM B ND 1 HETATM 9851 FE FE . HEM AA 6 . ? 38.695 32.084 32.605 1.00 12.52 ? 605 HEM B FE 1 HETATM 9852 C C . FMT BA 7 . ? 57.389 20.467 53.419 1.00 36.99 ? 3004 FMT B C 1 HETATM 9853 O O1 . FMT BA 7 . ? 57.037 20.775 54.536 1.00 37.54 ? 3004 FMT B O1 1 HETATM 9854 O O2 . FMT BA 7 . ? 58.177 21.287 52.697 1.00 36.10 ? 3004 FMT B O2 1 HETATM 9855 C C . FMT CA 7 . ? 30.104 48.346 29.428 1.00 4.84 ? 3005 FMT B C 1 HETATM 9856 O O1 . FMT CA 7 . ? 29.211 48.508 28.629 1.00 5.53 ? 3005 FMT B O1 1 HETATM 9857 O O2 . FMT CA 7 . ? 30.125 47.246 30.187 1.00 3.97 ? 3005 FMT B O2 1 HETATM 9858 C C . FMT DA 7 . ? 36.234 29.257 34.063 1.00 19.19 ? 3006 FMT B C 1 HETATM 9859 O O1 . FMT DA 7 . ? 36.585 30.164 34.791 1.00 18.73 ? 3006 FMT B O1 1 HETATM 9860 O O2 . FMT DA 7 . ? 34.924 28.975 33.883 1.00 19.97 ? 3006 FMT B O2 1 HETATM 9861 O O . HOH EA 8 . ? 13.265 3.671 5.299 1.00 21.85 ? 3004 HOH A O 1 HETATM 9862 O O . HOH EA 8 . ? 11.453 6.608 5.380 1.00 12.24 ? 3005 HOH A O 1 HETATM 9863 O O . HOH EA 8 . ? -0.585 -6.332 -21.554 1.00 24.14 ? 3006 HOH A O 1 HETATM 9864 O O . HOH EA 8 . ? 12.168 -17.863 -12.658 1.00 5.02 ? 3007 HOH A O 1 HETATM 9865 O O . HOH EA 8 . ? 12.470 -18.719 -22.997 1.00 15.42 ? 3008 HOH A O 1 HETATM 9866 O O . HOH EA 8 . ? -16.667 1.968 -34.226 1.00 15.32 ? 3009 HOH A O 1 HETATM 9867 O O . HOH EA 8 . ? -17.981 -0.955 -35.260 1.00 17.24 ? 3010 HOH A O 1 HETATM 9868 O O . HOH EA 8 . ? 23.164 11.825 21.111 1.00 14.49 ? 3011 HOH A O 1 HETATM 9869 O O . HOH EA 8 . ? -7.605 21.010 16.725 1.00 2.00 ? 3012 HOH A O 1 HETATM 9870 O O . HOH EA 8 . ? -6.806 5.372 -37.072 1.00 2.89 ? 3013 HOH A O 1 HETATM 9871 O O . HOH EA 8 . ? -10.514 -8.014 -18.552 1.00 2.00 ? 3014 HOH A O 1 HETATM 9872 O O . HOH EA 8 . ? -9.433 -11.142 3.704 1.00 2.00 ? 3015 HOH A O 1 HETATM 9873 O O . HOH EA 8 . ? -13.842 22.170 -16.058 1.00 2.88 ? 3016 HOH A O 1 HETATM 9874 O O . HOH EA 8 . ? 2.546 -2.432 31.802 1.00 7.03 ? 3017 HOH A O 1 HETATM 9875 O O . HOH EA 8 . ? 14.677 -11.494 6.150 1.00 2.00 ? 3018 HOH A O 1 HETATM 9876 O O . HOH EA 8 . ? -9.233 -6.439 5.773 1.00 2.00 ? 3019 HOH A O 1 HETATM 9877 O O . HOH EA 8 . ? 10.119 17.153 15.723 1.00 10.55 ? 3020 HOH A O 1 HETATM 9878 O O . HOH EA 8 . ? 6.697 21.631 14.361 1.00 22.31 ? 3021 HOH A O 1 HETATM 9879 O O . HOH EA 8 . ? 24.177 -12.984 7.247 1.00 2.00 ? 3022 HOH A O 1 HETATM 9880 O O . HOH EA 8 . ? 19.371 -0.830 -29.612 1.00 18.66 ? 3023 HOH A O 1 HETATM 9881 O O . HOH EA 8 . ? 23.639 14.381 24.992 1.00 6.68 ? 3024 HOH A O 1 HETATM 9882 O O . HOH EA 8 . ? 17.296 12.716 -4.480 1.00 18.17 ? 3025 HOH A O 1 HETATM 9883 O O . HOH EA 8 . ? -1.848 -10.672 9.545 1.00 4.56 ? 3026 HOH A O 1 HETATM 9884 O O . HOH EA 8 . ? -7.419 -21.539 -26.141 1.00 5.34 ? 3027 HOH A O 1 HETATM 9885 O O . HOH EA 8 . ? 6.191 14.524 12.857 1.00 3.69 ? 3028 HOH A O 1 HETATM 9886 O O . HOH EA 8 . ? 4.823 16.710 -20.088 1.00 7.36 ? 3029 HOH A O 1 HETATM 9887 O O . HOH EA 8 . ? 10.078 13.699 -20.319 1.00 13.87 ? 3030 HOH A O 1 HETATM 9888 O O . HOH EA 8 . ? -3.527 -6.985 -19.932 1.00 2.00 ? 3031 HOH A O 1 HETATM 9889 O O . HOH EA 8 . ? -9.277 5.447 -35.880 1.00 12.85 ? 3032 HOH A O 1 HETATM 9890 O O . HOH EA 8 . ? 1.969 -17.976 -0.066 1.00 17.38 ? 3033 HOH A O 1 HETATM 9891 O O . HOH EA 8 . ? -0.138 29.865 0.036 1.00 3.57 ? 3034 HOH A O 1 HETATM 9892 O O . HOH EA 8 . ? -9.958 -21.441 14.277 1.00 7.80 ? 3035 HOH A O 1 HETATM 9893 O O . HOH EA 8 . ? 17.769 7.803 8.228 1.00 31.02 ? 3036 HOH A O 1 HETATM 9894 O O . HOH EA 8 . ? -24.848 8.220 -3.165 1.00 9.80 ? 3037 HOH A O 1 HETATM 9895 O O . HOH EA 8 . ? 20.329 5.420 -2.765 1.00 2.00 ? 3038 HOH A O 1 HETATM 9896 O O . HOH EA 8 . ? 22.567 -11.513 9.797 1.00 2.04 ? 3039 HOH A O 1 HETATM 9897 O O . HOH EA 8 . ? 5.160 4.077 24.042 1.00 4.17 ? 3040 HOH A O 1 HETATM 9898 O O . HOH EA 8 . ? 0.132 -19.656 5.579 1.00 30.24 ? 3041 HOH A O 1 HETATM 9899 O O . HOH EA 8 . ? -1.117 20.792 -17.810 1.00 2.00 ? 3042 HOH A O 1 HETATM 9900 O O . HOH EA 8 . ? -1.086 -6.323 -26.000 1.00 51.52 ? 3043 HOH A O 1 HETATM 9901 O O . HOH EA 8 . ? -5.789 22.788 14.765 1.00 14.46 ? 3044 HOH A O 1 HETATM 9902 O O . HOH EA 8 . ? 20.340 5.223 -0.113 1.00 8.05 ? 3045 HOH A O 1 HETATM 9903 O O . HOH EA 8 . ? -9.746 -9.172 5.467 1.00 4.70 ? 3046 HOH A O 1 HETATM 9904 O O . HOH EA 8 . ? -10.602 17.250 14.689 1.00 2.00 ? 3047 HOH A O 1 HETATM 9905 O O . HOH EA 8 . ? 8.786 17.707 18.528 1.00 29.98 ? 3048 HOH A O 1 HETATM 9906 O O . HOH EA 8 . ? 12.260 -1.270 32.392 1.00 14.00 ? 3049 HOH A O 1 HETATM 9907 O O . HOH EA 8 . ? -20.049 3.391 4.788 1.00 25.07 ? 3050 HOH A O 1 HETATM 9908 O O . HOH EA 8 . ? -17.660 4.898 -33.487 1.00 35.90 ? 3051 HOH A O 1 HETATM 9909 O O . HOH EA 8 . ? -26.419 -3.113 -3.650 1.00 50.74 ? 3052 HOH A O 1 HETATM 9910 O O . HOH EA 8 . ? -23.474 15.280 -6.191 1.00 45.85 ? 3053 HOH A O 1 HETATM 9911 O O . HOH EA 8 . ? -19.336 15.105 -5.708 1.00 45.18 ? 3054 HOH A O 1 HETATM 9912 O O . HOH EA 8 . ? 0.691 -10.533 -25.982 1.00 56.08 ? 3055 HOH A O 1 HETATM 9913 O O . HOH EA 8 . ? -16.907 -9.614 10.574 1.00 33.56 ? 3056 HOH A O 1 HETATM 9914 O O . HOH EA 8 . ? -13.626 -11.342 -8.373 1.00 32.65 ? 3057 HOH A O 1 HETATM 9915 O O . HOH EA 8 . ? -12.541 -4.537 9.184 1.00 16.87 ? 3058 HOH A O 1 HETATM 9916 O O . HOH EA 8 . ? 10.785 7.353 -15.365 1.00 19.71 ? 3059 HOH A O 1 HETATM 9917 O O . HOH EA 8 . ? 11.622 -11.767 0.389 1.00 23.72 ? 3060 HOH A O 1 HETATM 9918 O O . HOH EA 8 . ? 2.723 9.242 -19.509 1.00 20.21 ? 3061 HOH A O 1 HETATM 9919 O O . HOH EA 8 . ? -5.971 -9.709 16.980 1.00 19.60 ? 3062 HOH A O 1 HETATM 9920 O O . HOH EA 8 . ? 17.196 -8.306 -16.052 1.00 22.03 ? 3063 HOH A O 1 HETATM 9921 O O . HOH EA 8 . ? -5.696 9.459 -9.888 1.00 14.35 ? 3064 HOH A O 1 HETATM 9922 O O . HOH EA 8 . ? 4.659 -17.823 -21.920 1.00 24.65 ? 3065 HOH A O 1 HETATM 9923 O O . HOH EA 8 . ? 5.027 6.096 -6.046 1.00 6.39 ? 3066 HOH A O 1 HETATM 9924 O O . HOH EA 8 . ? 3.074 -17.870 -2.372 1.00 13.72 ? 3067 HOH A O 1 HETATM 9925 O O . HOH EA 8 . ? 4.816 31.192 -16.784 1.00 22.86 ? 3068 HOH A O 1 HETATM 9926 O O . HOH EA 8 . ? -8.307 24.201 11.025 1.00 25.33 ? 3069 HOH A O 1 HETATM 9927 O O . HOH EA 8 . ? 3.611 8.199 -13.552 1.00 12.03 ? 3070 HOH A O 1 HETATM 9928 O O . HOH EA 8 . ? 16.264 5.532 29.629 1.00 40.52 ? 3071 HOH A O 1 HETATM 9929 O O . HOH EA 8 . ? 13.920 11.009 -17.886 1.00 33.06 ? 3072 HOH A O 1 HETATM 9930 O O . HOH EA 8 . ? 15.375 7.550 9.998 1.00 41.68 ? 3073 HOH A O 1 HETATM 9931 O O . HOH EA 8 . ? -0.741 8.069 -16.605 1.00 22.34 ? 3074 HOH A O 1 HETATM 9932 O O . HOH EA 8 . ? -1.324 26.066 -6.370 1.00 52.53 ? 3075 HOH A O 1 HETATM 9933 O O . HOH EA 8 . ? 9.265 13.240 -4.914 1.00 34.39 ? 3076 HOH A O 1 HETATM 9934 O O . HOH EA 8 . ? -6.425 22.333 8.877 1.00 23.69 ? 3077 HOH A O 1 HETATM 9935 O O . HOH EA 8 . ? 2.787 3.250 -39.196 1.00 35.11 ? 3078 HOH A O 1 HETATM 9936 O O . HOH EA 8 . ? -10.276 -18.815 -13.832 1.00 36.98 ? 3079 HOH A O 1 HETATM 9937 O O . HOH EA 8 . ? 25.869 11.726 21.314 1.00 50.36 ? 3080 HOH A O 1 HETATM 9938 O O . HOH EA 8 . ? 6.457 -9.412 37.623 1.00 32.35 ? 3081 HOH A O 1 HETATM 9939 O O . HOH EA 8 . ? -4.947 13.083 -26.473 1.00 37.28 ? 3082 HOH A O 1 HETATM 9940 O O . HOH EA 8 . ? -14.289 -20.912 -1.843 1.00 51.37 ? 3083 HOH A O 1 HETATM 9941 O O . HOH EA 8 . ? -4.897 20.970 11.608 1.00 43.71 ? 3084 HOH A O 1 HETATM 9942 O O . HOH EA 8 . ? -2.728 12.036 -28.108 1.00 32.46 ? 3085 HOH A O 1 HETATM 9943 O O . HOH EA 8 . ? 2.125 -16.823 13.550 1.00 29.07 ? 3086 HOH A O 1 HETATM 9944 O O . HOH EA 8 . ? 0.789 -0.998 30.901 1.00 60.49 ? 3087 HOH A O 1 HETATM 9945 O O . HOH EA 8 . ? 2.368 0.074 -40.053 1.00 52.79 ? 3088 HOH A O 1 HETATM 9946 O O . HOH EA 8 . ? -8.841 -22.613 5.657 1.00 37.86 ? 3089 HOH A O 1 HETATM 9947 O O . HOH FA 8 . ? 32.479 31.041 32.974 1.00 21.85 ? 3007 HOH B O 1 HETATM 9948 O O . HOH FA 8 . ? 26.704 28.196 32.253 1.00 30.67 ? 3008 HOH B O 1 HETATM 9949 O O . HOH FA 8 . ? 26.963 25.680 35.842 1.00 20.46 ? 3009 HOH B O 1 HETATM 9950 O O . HOH FA 8 . ? 22.490 49.086 33.523 1.00 2.00 ? 3010 HOH B O 1 HETATM 9951 O O . HOH FA 8 . ? 52.015 23.776 60.438 1.00 2.00 ? 3011 HOH B O 1 HETATM 9952 O O . HOH FA 8 . ? 29.208 15.491 21.220 1.00 2.00 ? 3012 HOH B O 1 HETATM 9953 O O . HOH FA 8 . ? 19.962 35.381 19.574 1.00 2.00 ? 3013 HOH B O 1 HETATM 9954 O O . HOH FA 8 . ? 32.071 19.186 58.568 1.00 11.05 ? 3014 HOH B O 1 HETATM 9955 O O . HOH FA 8 . ? 27.596 26.220 41.837 1.00 17.61 ? 3015 HOH B O 1 HETATM 9956 O O . HOH FA 8 . ? 59.892 55.445 38.411 1.00 2.07 ? 3016 HOH B O 1 HETATM 9957 O O . HOH FA 8 . ? 33.888 2.857 35.469 1.00 28.08 ? 3017 HOH B O 1 HETATM 9958 O O . HOH FA 8 . ? 37.758 55.660 10.848 1.00 2.00 ? 3018 HOH B O 1 HETATM 9959 O O . HOH FA 8 . ? 13.955 49.982 22.895 1.00 18.87 ? 3019 HOH B O 1 HETATM 9960 O O . HOH FA 8 . ? 31.961 35.543 78.538 1.00 2.00 ? 3020 HOH B O 1 HETATM 9961 O O . HOH FA 8 . ? 48.214 31.249 28.242 1.00 7.68 ? 3021 HOH B O 1 HETATM 9962 O O . HOH FA 8 . ? 7.271 38.167 41.467 1.00 2.00 ? 3022 HOH B O 1 HETATM 9963 O O . HOH FA 8 . ? 33.477 21.547 17.408 1.00 2.00 ? 3023 HOH B O 1 HETATM 9964 O O . HOH FA 8 . ? 33.786 19.084 60.714 1.00 2.70 ? 3024 HOH B O 1 HETATM 9965 O O . HOH FA 8 . ? 44.535 32.558 58.685 1.00 26.58 ? 3025 HOH B O 1 HETATM 9966 O O . HOH FA 8 . ? 10.313 37.647 43.017 1.00 13.00 ? 3026 HOH B O 1 HETATM 9967 O O . HOH FA 8 . ? 31.931 28.731 27.871 1.00 2.00 ? 3027 HOH B O 1 HETATM 9968 O O . HOH FA 8 . ? 22.193 30.090 54.675 1.00 14.55 ? 3028 HOH B O 1 HETATM 9969 O O . HOH FA 8 . ? 32.151 36.966 10.231 1.00 4.30 ? 3029 HOH B O 1 HETATM 9970 O O . HOH FA 8 . ? 20.699 35.176 53.627 1.00 24.28 ? 3030 HOH B O 1 HETATM 9971 O O . HOH FA 8 . ? 22.049 50.744 21.076 1.00 11.20 ? 3031 HOH B O 1 HETATM 9972 O O . HOH FA 8 . ? 28.675 29.701 30.755 1.00 12.53 ? 3032 HOH B O 1 HETATM 9973 O O . HOH FA 8 . ? 54.613 33.950 17.656 1.00 3.79 ? 3033 HOH B O 1 HETATM 9974 O O . HOH FA 8 . ? 58.629 57.793 37.913 1.00 10.81 ? 3034 HOH B O 1 HETATM 9975 O O . HOH FA 8 . ? 56.202 58.696 36.376 1.00 20.93 ? 3035 HOH B O 1 HETATM 9976 O O . HOH FA 8 . ? 19.024 26.704 57.142 1.00 15.58 ? 3036 HOH B O 1 HETATM 9977 O O . HOH FA 8 . ? 34.243 16.830 59.293 1.00 9.50 ? 3037 HOH B O 1 HETATM 9978 O O . HOH FA 8 . ? 14.770 44.330 32.580 1.00 13.29 ? 3038 HOH B O 1 HETATM 9979 O O . HOH FA 8 . ? 27.600 42.473 11.041 1.00 21.78 ? 3039 HOH B O 1 HETATM 9980 O O . HOH FA 8 . ? 43.542 25.395 0.204 1.00 17.18 ? 3040 HOH B O 1 HETATM 9981 O O . HOH FA 8 . ? 27.794 58.576 52.148 1.00 34.94 ? 3041 HOH B O 1 HETATM 9982 O O . HOH FA 8 . ? 23.712 52.193 28.169 1.00 18.35 ? 3042 HOH B O 1 HETATM 9983 O O . HOH FA 8 . ? 45.907 57.593 14.108 1.00 36.27 ? 3043 HOH B O 1 HETATM 9984 O O . HOH FA 8 . ? 19.910 35.792 44.278 1.00 26.71 ? 3044 HOH B O 1 HETATM 9985 O O . HOH FA 8 . ? 36.384 43.363 79.493 1.00 41.98 ? 3045 HOH B O 1 HETATM 9986 O O . HOH FA 8 . ? 8.475 37.713 52.486 1.00 35.81 ? 3046 HOH B O 1 HETATM 9987 O O . HOH FA 8 . ? 33.726 60.019 53.799 1.00 54.95 ? 3047 HOH B O 1 HETATM 9988 O O . HOH FA 8 . ? 19.652 40.486 55.840 1.00 17.54 ? 3048 HOH B O 1 HETATM 9989 O O . HOH FA 8 . ? 22.705 49.571 26.286 1.00 24.56 ? 3049 HOH B O 1 HETATM 9990 O O . HOH FA 8 . ? 23.945 42.227 39.718 1.00 10.65 ? 3050 HOH B O 1 HETATM 9991 O O . HOH FA 8 . ? 47.998 16.060 50.268 1.00 17.08 ? 3051 HOH B O 1 HETATM 9992 O O . HOH FA 8 . ? 45.064 15.756 23.817 1.00 29.06 ? 3052 HOH B O 1 HETATM 9993 O O . HOH FA 8 . ? 48.430 44.145 28.804 1.00 16.73 ? 3053 HOH B O 1 HETATM 9994 O O . HOH FA 8 . ? 34.433 33.046 13.602 1.00 15.28 ? 3054 HOH B O 1 HETATM 9995 O O . HOH FA 8 . ? 26.688 28.666 52.916 1.00 17.42 ? 3055 HOH B O 1 HETATM 9996 O O . HOH FA 8 . ? 28.203 25.570 31.702 1.00 20.66 ? 3056 HOH B O 1 HETATM 9997 O O . HOH FA 8 . ? 27.462 28.616 40.450 1.00 25.05 ? 3057 HOH B O 1 HETATM 9998 O O . HOH FA 8 . ? 21.427 37.883 57.117 1.00 23.66 ? 3058 HOH B O 1 HETATM 9999 O O . HOH FA 8 . ? 21.829 51.292 30.317 1.00 25.03 ? 3059 HOH B O 1 HETATM 10000 O O . HOH FA 8 . ? 31.072 11.881 50.942 1.00 45.28 ? 3060 HOH B O 1 HETATM 10001 O O . HOH FA 8 . ? 61.621 34.635 29.732 1.00 34.28 ? 3061 HOH B O 1 HETATM 10002 O O . HOH FA 8 . ? 43.911 21.401 16.400 1.00 39.20 ? 3062 HOH B O 1 HETATM 10003 O O . HOH FA 8 . ? 38.160 36.356 8.729 1.00 22.79 ? 3063 HOH B O 1 HETATM 10004 O O . HOH FA 8 . ? 43.839 18.912 14.208 1.00 41.98 ? 3064 HOH B O 1 HETATM 10005 O O . HOH FA 8 . ? 21.179 27.661 55.154 1.00 34.64 ? 3065 HOH B O 1 HETATM 10006 O O . HOH FA 8 . ? 34.718 19.927 4.838 1.00 36.40 ? 3066 HOH B O 1 HETATM 10007 O O . HOH FA 8 . ? 29.191 44.769 64.492 1.00 50.08 ? 3067 HOH B O 1 HETATM 10008 O O . HOH FA 8 . ? 46.280 27.062 10.194 1.00 43.57 ? 3068 HOH B O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 SER 1 1 1 SER SER A . n A 1 2 TRP 2 2 2 TRP TRP A . n A 1 3 GLU 3 3 3 GLU GLU A . n A 1 4 VAL 4 4 4 VAL VAL A . n A 1 5 GLY 5 5 5 GLY GLY A . n A 1 6 CYS 6 6 6 CYS CYS A . n A 1 7 GLY 7 7 7 GLY GLY A . n A 1 8 ALA 8 8 8 ALA ALA A . n A 1 9 PRO 9 9 9 PRO PRO A . n A 1 10 VAL 10 10 10 VAL VAL A . n A 1 11 PRO 11 11 11 PRO PRO A . n A 1 12 LEU 12 12 12 LEU LEU A . n A 1 13 VAL 13 13 13 VAL VAL A . n A 1 14 LYS 14 14 14 LYS LYS A . n A 1 15 CYS 15 15 15 CYS CYS A . n A 1 16 ASP 16 16 16 ASP ASP A . n A 1 17 GLU 17 17 17 GLU GLU A . n A 1 18 ASN 18 18 18 ASN ASN A . n A 1 19 SER 19 19 19 SER SER A . n A 1 20 PRO 20 20 20 PRO PRO A . n A 1 21 TYR 21 21 21 TYR TYR A . n A 1 22 ARG 22 22 22 ARG ARG A . n A 1 23 THR 23 23 23 THR THR A . n A 1 24 ILE 24 24 24 ILE ILE A . n A 1 25 THR 25 25 25 THR THR A . n A 1 26 GLY 26 26 26 GLY GLY A . n A 1 27 ASP 27 27 27 ASP ASP A . n A 1 28 CYS 28 28 28 CYS CYS A . n A 1 29 ASN 29 29 29 ASN ASN A . n A 1 30 ASN 30 30 30 ASN ASN A . n A 1 31 ARG 31 31 31 ARG ARG A . n A 1 32 ARG 32 32 32 ARG ARG A . n A 1 33 SER 33 33 33 SER SER A . n A 1 34 PRO 34 34 34 PRO PRO A . n A 1 35 ALA 35 35 35 ALA ALA A . n A 1 36 LEU 36 36 36 LEU LEU A . n A 1 37 GLY 37 37 37 GLY GLY A . n A 1 38 ALA 38 38 38 ALA ALA A . n A 1 39 ALA 39 39 39 ALA ALA A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 ARG 41 41 41 ARG ARG A . n A 1 42 ALA 42 42 42 ALA ALA A . n A 1 43 LEU 43 43 43 LEU LEU A . n A 1 44 ALA 44 44 44 ALA ALA A . n A 1 45 ARG 45 45 45 ARG ARG A . n A 1 46 TRP 46 46 46 TRP TRP A . n A 1 47 LEU 47 47 47 LEU LEU A . n A 1 48 PRO 48 48 48 PRO PRO A . n A 1 49 ALA 49 49 49 ALA ALA A . n A 1 50 GLU 50 50 50 GLU GLU A . n A 1 51 TYR 51 51 51 TYR TYR A . n A 1 52 GLU 52 52 52 GLU GLU A . n A 1 53 ASP 53 53 53 ASP ASP A . n A 1 54 GLY 54 54 54 GLY GLY A . n A 1 55 LEU 55 55 55 LEU LEU A . n A 1 56 ALA 56 56 56 ALA ALA A . n A 1 57 VAL 57 57 57 VAL VAL A . n A 1 58 PRO 58 58 58 PRO PRO A . n A 1 59 PHE 59 59 59 PHE PHE A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 TRP 61 61 61 TRP TRP A . n A 1 62 THR 62 62 62 THR THR A . n A 1 63 GLN 63 63 63 GLN GLN A . n A 1 64 ARG 64 64 64 ARG ARG A . n A 1 65 LYS 65 65 65 LYS LYS A . n A 1 66 THR 66 66 66 THR THR A . n A 1 67 ARG 67 67 67 ARG ARG A . n A 1 68 ASN 68 68 68 ASN ASN A . n A 1 69 GLY 69 69 69 GLY GLY A . n A 1 70 PHE 70 70 70 PHE PHE A . n A 1 71 ARG 71 71 71 ARG ARG A . n A 1 72 VAL 72 72 72 VAL VAL A . n A 1 73 PRO 73 73 73 PRO PRO A . n A 1 74 LEU 74 74 74 LEU LEU A . n A 1 75 ALA 75 75 75 ALA ALA A . n A 1 76 ARG 76 76 76 ARG ARG A . n A 1 77 GLU 77 77 77 GLU GLU A . n A 1 78 VAL 78 78 78 VAL VAL A . n A 1 79 SER 79 79 79 SER SER A . n A 1 80 ASN 80 80 80 ASN ASN A . n A 1 81 LYS 81 81 81 LYS LYS A . n A 1 82 ILE 82 82 82 ILE ILE A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 GLY 84 84 84 GLY GLY A . n A 1 85 TYR 85 85 85 TYR TYR A . n A 1 86 LEU 86 86 86 LEU LEU A . n A 1 87 ASP 87 87 87 ASP ASP A . n A 1 88 GLU 88 88 88 GLU GLU A . n A 1 89 GLU 89 89 89 GLU GLU A . n A 1 90 GLY 90 90 90 GLY GLY A . n A 1 91 VAL 91 91 91 VAL VAL A . n A 1 92 LEU 92 92 92 LEU LEU A . n A 1 93 ASP 93 93 93 ASP ASP A . n A 1 94 GLN 94 94 94 GLN GLN A . n A 1 95 ASN 95 95 95 ASN ASN A . n A 1 96 ARG 96 96 96 ARG ARG A . n A 1 97 SER 97 97 97 SER SER A . n A 1 98 LEU 98 98 98 LEU LEU A . n A 1 99 LEU 99 99 99 LEU LEU A . n A 1 100 PHE 100 100 100 PHE PHE A . n A 1 101 MET 101 101 101 MET MET A . n A 1 102 GLN 102 102 102 GLN GLN A . n A 1 103 TRP 103 103 103 TRP TRP A . n A 1 104 GLY 104 104 104 GLY GLY A . n A 1 105 GLN 105 105 105 GLN GLN A . n A 1 106 ILE 106 106 106 ILE ILE A . n A 1 107 VAL 107 107 107 VAL VAL A . n A 1 108 ASP 108 108 108 ASP ASP A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ASP 110 110 110 ASP ASP A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 ASP 112 112 112 ASP ASP A . n A 1 113 PHE 113 113 113 PHE PHE A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 PRO 115 115 115 PRO PRO A . n A 1 116 GLU 116 116 116 GLU GLU A . n A 1 117 THR 117 117 117 THR THR A . n A 1 118 GLU 118 118 118 GLU GLU A . n A 1 119 LEU 119 119 119 LEU LEU A . n A 1 120 GLY 120 120 120 GLY GLY A . n A 1 121 SER 121 121 121 SER SER A . n A 1 122 SER 122 122 122 SER SER A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 HIS 124 124 124 HIS HIS A . n A 1 125 SER 125 125 125 SER SER A . n A 1 126 LYS 126 126 126 LYS LYS A . n A 1 127 VAL 127 127 127 VAL VAL A . n A 1 128 GLN 128 128 128 GLN GLN A . n A 1 129 CYS 129 129 129 CYS CYS A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 GLU 131 131 131 GLU GLU A . n A 1 132 TYR 132 132 132 TYR TYR A . n A 1 133 CYS 133 133 133 CYS CYS A . n A 1 134 ILE 134 134 134 ILE ILE A . n A 1 135 GLN 135 135 135 GLN GLN A . n A 1 136 GLY 136 136 136 GLY GLY A . n A 1 137 ASP 137 137 137 ASP ASP A . n A 1 138 ASN 138 138 138 ASN ASN A . n A 1 139 CYS 139 139 139 CYS CYS A . n A 1 140 PHE 140 140 140 PHE PHE A . n A 1 141 PRO 141 141 141 PRO PRO A . n A 1 142 ILE 142 142 142 ILE ILE A . n A 1 143 MET 143 143 143 MET MET A . n A 1 144 PHE 144 144 144 PHE PHE A . n A 1 145 PRO 145 145 145 PRO PRO A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 ASN 147 147 147 ASN ASN A . n A 1 148 ASP 148 148 148 ASP ASP A . n A 1 149 PRO 149 149 149 PRO PRO A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 LEU 151 151 151 LEU LEU A . n A 1 152 LYS 152 152 152 LYS LYS A . n A 1 153 THR 153 153 153 THR THR A . n A 1 154 GLN 154 154 154 GLN GLN A . n A 1 155 GLY 155 155 155 GLY GLY A . n A 1 156 LYS 156 156 156 LYS LYS A . n A 1 157 CYS 157 157 157 CYS CYS A . n A 1 158 MET 158 158 158 MET MET A . n A 1 159 PRO 159 159 159 PRO PRO A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 PHE 161 161 161 PHE PHE A . n A 1 162 ARG 162 162 162 ARG ARG A . n A 1 163 ALA 163 163 163 ALA ALA A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 PHE 165 165 165 PHE PHE A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 CYS 167 167 167 CYS CYS A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 THR 169 169 169 THR THR A . n A 1 170 PRO 170 170 170 PRO PRO A . n A 1 171 PRO 171 171 171 PRO PRO A . n A 1 172 TYR 172 172 172 TYR TYR A . n A 1 173 GLN 173 173 173 GLN GLN A . n A 1 174 SER 174 174 174 SER SER A . n A 1 175 LEU 175 175 175 LEU LEU A . n A 1 176 ALA 176 176 176 ALA ALA A . n A 1 177 ARG 177 177 177 ARG ARG A . n A 1 178 ASP 178 178 178 ASP ASP A . n A 1 179 GLN 179 179 179 GLN GLN A . n A 1 180 ILE 180 180 180 ILE ILE A . n A 1 181 ASN 181 181 181 ASN ASN A . n A 1 182 SER 182 182 182 SER SER A . n A 1 183 VAL 183 183 183 VAL VAL A . n A 1 184 THR 184 184 184 THR THR A . n A 1 185 SER 185 185 185 SER SER A . n A 1 186 PHE 186 186 186 PHE PHE A . n A 1 187 LEU 187 187 187 LEU LEU A . n A 1 188 ASP 188 188 188 ASP ASP A . n A 1 189 ALA 189 189 189 ALA ALA A . n A 1 190 SER 190 190 190 SER SER A . n A 1 191 LEU 191 191 191 LEU LEU A . n A 1 192 VAL 192 192 192 VAL VAL A . n A 1 193 TYR 193 193 193 TYR TYR A . n A 1 194 GLY 194 194 194 GLY GLY A . n A 1 195 SER 195 195 195 SER SER A . n A 1 196 GLU 196 196 196 GLU GLU A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 SER 198 198 198 SER SER A . n A 1 199 LEU 199 199 199 LEU LEU A . n A 1 200 ALA 200 200 200 ALA ALA A . n A 1 201 SER 201 201 201 SER SER A . n A 1 202 ARG 202 202 202 ARG ARG A . n A 1 203 LEU 203 203 203 LEU LEU A . n A 1 204 ARG 204 204 204 ARG ARG A . n A 1 205 ASN 205 205 205 ASN ASN A . n A 1 206 LEU 206 206 206 LEU LEU A . n A 1 207 SER 207 207 207 SER SER A . n A 1 208 SER 208 208 208 SER SER A . n A 1 209 PRO 209 209 209 PRO PRO A . n A 1 210 LEU 210 210 210 LEU LEU A . n A 1 211 GLY 211 211 211 GLY GLY A . n A 1 212 LEU 212 212 212 LEU LEU A . n A 1 213 MET 213 213 213 MET MET A . n A 1 214 ALA 214 214 214 ALA ALA A . n A 1 215 VAL 215 215 215 VAL VAL A . n A 1 216 ASN 216 216 216 ASN ASN A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 GLU 218 218 218 GLU GLU A . n A 1 219 ALA 219 219 219 ALA ALA A . n A 1 220 TRP 220 220 220 TRP TRP A . n A 1 221 ASP 221 221 221 ASP ASP A . n A 1 222 HIS 222 222 222 HIS HIS A . n A 1 223 GLY 223 223 223 GLY GLY A . n A 1 224 LEU 224 224 224 LEU LEU A . n A 1 225 ALA 225 225 225 ALA ALA A . n A 1 226 TYR 226 226 226 TYR TYR A . n A 1 227 PRO 227 227 227 PRO PRO A . n A 1 228 PRO 228 228 228 PRO PRO A . n A 1 229 PHE 229 229 229 PHE PHE A . n A 1 230 ASN 230 230 230 ASN ASN A . n A 1 231 ASN 231 231 231 ASN ASN A . n A 1 232 MET 232 232 232 MET MET A . n A 1 233 LYS 233 233 233 LYS LYS A . n A 1 234 PRO 234 234 234 PRO PRO A . n A 1 235 SER 235 235 235 SER SER A . n A 1 236 PRO 236 236 236 PRO PRO A . n A 1 237 CYS 237 237 237 CYS CYS A . n A 1 238 GLU 238 238 238 GLU GLU A . n A 1 239 PHE 239 239 239 PHE PHE A . n A 1 240 ILE 240 240 240 ILE ILE A . n A 1 241 ASN 241 241 241 ASN ASN A . n A 1 242 THR 242 242 242 THR THR A . n A 1 243 THR 243 243 243 THR THR A . n A 1 244 ALA 244 244 244 ALA ALA A . n A 1 245 ARG 245 245 245 ARG ARG A . n A 1 246 VAL 246 246 246 VAL VAL A . n A 1 247 PRO 247 247 247 PRO PRO A . n A 1 248 CYS 248 248 248 CYS CYS A . n A 1 249 PHE 249 249 249 PHE PHE A . n A 1 250 GLN 250 250 250 GLN GLN A . n A 1 251 ALA 251 251 251 ALA ALA A . n A 1 252 GLY 252 252 252 GLY GLY A . n A 1 253 ASP 253 253 253 ASP ASP A . n A 1 254 SER 254 254 254 SER SER A . n A 1 255 ARG 255 255 255 ARG ARG A . n A 1 256 ALA 256 256 256 ALA ALA A . n A 1 257 SER 257 257 257 SER SER A . n A 1 258 GLU 258 258 258 GLU GLU A . n A 1 259 GLN 259 259 259 GLN GLN A . n A 1 260 ILE 260 260 260 ILE ILE A . n A 1 261 LEU 261 261 261 LEU LEU A . n A 1 262 LEU 262 262 262 LEU LEU A . n A 1 263 ALA 263 263 263 ALA ALA A . n A 1 264 THR 264 264 264 THR THR A . n A 1 265 VAL 265 265 265 VAL VAL A . n A 1 266 HIS 266 266 266 HIS HIS A . n A 1 267 THR 267 267 267 THR THR A . n A 1 268 LEU 268 268 268 LEU LEU A . n A 1 269 LEU 269 269 269 LEU LEU A . n A 1 270 LEU 270 270 270 LEU LEU A . n A 1 271 ARG 271 271 271 ARG ARG A . n A 1 272 GLU 272 272 272 GLU GLU A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 ASN 274 274 274 ASN ASN A . n A 1 275 ARG 275 275 275 ARG ARG A . n A 1 276 LEU 276 276 276 LEU LEU A . n A 1 277 ALA 277 277 277 ALA ALA A . n A 1 278 ARG 278 278 278 ARG ARG A . n A 1 279 GLU 279 279 279 GLU GLU A . n A 1 280 LEU 280 280 280 LEU LEU A . n A 1 281 LYS 281 281 281 LYS LYS A . n A 1 282 ARG 282 282 282 ARG ARG A . n A 1 283 LEU 283 283 283 LEU LEU A . n A 1 284 ASN 284 284 284 ASN ASN A . n A 1 285 PRO 285 285 285 PRO PRO A . n A 1 286 HIS 286 286 286 HIS HIS A . n A 1 287 TRP 287 287 287 TRP TRP A . n A 1 288 ASP 288 288 288 ASP ASP A . n A 1 289 GLY 289 289 289 GLY GLY A . n A 1 290 GLU 290 290 290 GLU GLU A . n A 1 291 LYS 291 291 291 LYS LYS A . n A 1 292 LEU 292 292 292 LEU LEU A . n A 1 293 TYR 293 293 293 TYR TYR A . n A 1 294 GLN 294 294 294 GLN GLN A . n A 1 295 GLU 295 295 295 GLU GLU A . n A 1 296 ALA 296 296 296 ALA ALA A . n A 1 297 ARG 297 297 297 ARG ARG A . n A 1 298 LYS 298 298 298 LYS LYS A . n A 1 299 ILE 299 299 299 ILE ILE A . n A 1 300 LEU 300 300 300 LEU LEU A . n A 1 301 GLY 301 301 301 GLY GLY A . n A 1 302 ALA 302 302 302 ALA ALA A . n A 1 303 PHE 303 303 303 PHE PHE A . n A 1 304 ILE 304 304 304 ILE ILE A . n A 1 305 GLN 305 305 305 GLN GLN A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 ILE 307 307 307 ILE ILE A . n A 1 308 THR 308 308 308 THR THR A . n A 1 309 PHE 309 309 309 PHE PHE A . n A 1 310 ARG 310 310 310 ARG ARG A . n A 1 311 ASP 311 311 311 ASP ASP A . n A 1 312 TYR 312 312 312 TYR TYR A . n A 1 313 LEU 313 313 313 LEU LEU A . n A 1 314 PRO 314 314 314 PRO PRO A . n A 1 315 ILE 315 315 315 ILE ILE A . n A 1 316 VAL 316 316 316 VAL VAL A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 GLY 318 318 318 GLY GLY A . n A 1 319 SER 319 319 319 SER SER A . n A 1 320 GLU 320 320 320 GLU GLU A . n A 1 321 MET 321 321 321 MET MET A . n A 1 322 GLN 322 322 322 GLN GLN A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 TRP 324 324 324 TRP TRP A . n A 1 325 ILE 325 325 325 ILE ILE A . n A 1 326 PRO 326 326 326 PRO PRO A . n A 1 327 ARG 327 327 327 ARG ARG A . n A 1 328 TYR 328 328 328 TYR TYR A . n A 1 329 GLN 329 329 329 GLN GLN A . n A 1 330 GLY 330 330 330 GLY GLY A . n A 1 331 TYR 331 331 331 TYR TYR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 ASN 333 333 333 ASN ASN A . n A 1 334 SER 334 334 334 SER SER A . n A 1 335 VAL 335 335 335 VAL VAL A . n A 1 336 ASP 336 336 336 ASP ASP A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 ARG 338 338 338 ARG ARG A . n A 1 339 ILE 339 339 339 ILE ILE A . n A 1 340 SER 340 340 340 SER SER A . n A 1 341 ASN 341 341 341 ASN ASN A . n A 1 342 VAL 342 342 342 VAL VAL A . n A 1 343 PHE 343 343 343 PHE PHE A . n A 1 344 THR 344 344 344 THR THR A . n A 1 345 PHE 345 345 345 PHE PHE A . n A 1 346 ALA 346 346 346 ALA ALA A . n A 1 347 PHE 347 347 347 PHE PHE A . n A 1 348 ARG 348 348 348 ARG ARG A . n A 1 349 PHE 349 349 349 PHE PHE A . n A 1 350 GLY 350 350 350 GLY GLY A . n A 1 351 HIS 351 351 351 HIS HIS A . n A 1 352 MET 352 352 352 MET MET A . n A 1 353 GLU 353 353 353 GLU GLU A . n A 1 354 VAL 354 354 354 VAL VAL A . n A 1 355 PRO 355 355 355 PRO PRO A . n A 1 356 SER 356 356 356 SER SER A . n A 1 357 THR 357 357 357 THR THR A . n A 1 358 VAL 358 358 358 VAL VAL A . n A 1 359 SER 359 359 359 SER SER A . n A 1 360 ARG 360 360 360 ARG ARG A . n A 1 361 LEU 361 361 361 LEU LEU A . n A 1 362 ASP 362 362 362 ASP ASP A . n A 1 363 GLU 363 363 363 GLU GLU A . n A 1 364 ASN 364 364 364 ASN ASN A . n A 1 365 TYR 365 365 365 TYR TYR A . n A 1 366 GLN 366 366 366 GLN GLN A . n A 1 367 PRO 367 367 367 PRO PRO A . n A 1 368 ARG 368 368 368 ARG ARG A . n A 1 369 GLY 369 369 369 GLY GLY A . n A 1 370 PRO 370 370 370 PRO PRO A . n A 1 371 GLU 371 371 371 GLU GLU A . n A 1 372 ALA 372 372 372 ALA ALA A . n A 1 373 GLU 373 373 373 GLU GLU A . n A 1 374 LEU 374 374 374 LEU LEU A . n A 1 375 PRO 375 375 375 PRO PRO A . n A 1 376 LEU 376 376 376 LEU LEU A . n A 1 377 HIS 377 377 377 HIS HIS A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 PHE 380 380 380 PHE PHE A . n A 1 381 PHE 381 381 381 PHE PHE A . n A 1 382 ASN 382 382 382 ASN ASN A . n A 1 383 THR 383 383 383 THR THR A . n A 1 384 TRP 384 384 384 TRP TRP A . n A 1 385 ARG 385 385 385 ARG ARG A . n A 1 386 ILE 386 386 386 ILE ILE A . n A 1 387 ILE 387 387 387 ILE ILE A . n A 1 388 LYS 388 388 388 LYS LYS A . n A 1 389 ASP 389 389 389 ASP ASP A . n A 1 390 GLY 390 390 390 GLY GLY A . n A 1 391 GLY 391 391 391 GLY GLY A . n A 1 392 ILE 392 392 392 ILE ILE A . n A 1 393 ASP 393 393 393 ASP ASP A . n A 1 394 PRO 394 394 394 PRO PRO A . n A 1 395 LEU 395 395 395 LEU LEU A . n A 1 396 VAL 396 396 396 VAL VAL A . n A 1 397 ARG 397 397 397 ARG ARG A . n A 1 398 GLY 398 398 398 GLY GLY A . n A 1 399 LEU 399 399 399 LEU LEU A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 ALA 401 401 401 ALA ALA A . n A 1 402 LYS 402 402 402 LYS LYS A . n A 1 403 LYS 403 403 403 LYS LYS A . n A 1 404 SER 404 404 404 SER SER A . n A 1 405 LYS 405 405 405 LYS LYS A . n A 1 406 LEU 406 406 406 LEU LEU A . n A 1 407 MET 407 407 407 MET MET A . n A 1 408 ASN 408 408 408 ASN ASN A . n A 1 409 GLN 409 409 409 GLN GLN A . n A 1 410 ASN 410 410 410 ASN ASN A . n A 1 411 LYS 411 411 411 LYS LYS A . n A 1 412 MET 412 412 412 MET MET A . n A 1 413 VAL 413 413 413 VAL VAL A . n A 1 414 THR 414 414 414 THR THR A . n A 1 415 SER 415 415 415 SER SER A . n A 1 416 GLU 416 416 416 GLU GLU A . n A 1 417 LEU 417 417 417 LEU LEU A . n A 1 418 ARG 418 418 418 ARG ARG A . n A 1 419 ASN 419 419 419 ASN ASN A . n A 1 420 LYS 420 420 420 LYS LYS A . n A 1 421 LEU 421 421 421 LEU LEU A . n A 1 422 PHE 422 422 422 PHE PHE A . n A 1 423 GLN 423 423 423 GLN GLN A . n A 1 424 PRO 424 424 424 PRO PRO A . n A 1 425 THR 425 425 425 THR THR A . n A 1 426 HIS 426 426 426 HIS HIS A . n A 1 427 LYS 427 427 427 LYS LYS A . n A 1 428 ILE 428 428 428 ILE ILE A . n A 1 429 HIS 429 429 429 HIS HIS A . n A 1 430 GLY 430 430 430 GLY GLY A . n A 1 431 PHE 431 431 431 PHE PHE A . n A 1 432 ASP 432 432 432 ASP ASP A . n A 1 433 LEU 433 433 433 LEU LEU A . n A 1 434 ALA 434 434 434 ALA ALA A . n A 1 435 ALA 435 435 435 ALA ALA A . n A 1 436 ILE 436 436 436 ILE ILE A . n A 1 437 ASN 437 437 437 ASN ASN A . n A 1 438 LEU 438 438 438 LEU LEU A . n A 1 439 GLN 439 439 439 GLN GLN A . n A 1 440 ARG 440 440 440 ARG ARG A . n A 1 441 CYS 441 441 441 CYS CYS A . n A 1 442 ARG 442 442 442 ARG ARG A . n A 1 443 ASP 443 443 443 ASP ASP A . n A 1 444 HIS 444 444 444 HIS HIS A . n A 1 445 GLY 445 445 445 GLY GLY A . n A 1 446 MET 446 446 446 MET MET A . n A 1 447 PRO 447 447 447 PRO PRO A . n A 1 448 GLY 448 448 448 GLY GLY A . n A 1 449 TYR 449 449 449 TYR TYR A . n A 1 450 ASN 450 450 450 ASN ASN A . n A 1 451 SER 451 451 451 SER SER A . n A 1 452 TRP 452 452 452 TRP TRP A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 GLY 454 454 454 GLY GLY A . n A 1 455 PHE 455 455 455 PHE PHE A . n A 1 456 CYS 456 456 456 CYS CYS A . n A 1 457 GLY 457 457 457 GLY GLY A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 SER 459 459 459 SER SER A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 PRO 461 461 461 PRO PRO A . n A 1 462 LYS 462 462 462 LYS LYS A . n A 1 463 THR 463 463 463 THR THR A . n A 1 464 LEU 464 464 464 LEU LEU A . n A 1 465 LYS 465 465 465 LYS LYS A . n A 1 466 GLY 466 466 466 GLY GLY A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 GLN 468 468 468 GLN GLN A . n A 1 469 ALA 469 469 469 ALA ALA A . n A 1 470 VAL 470 470 470 VAL VAL A . n A 1 471 LEU 471 471 471 LEU LEU A . n A 1 472 LYS 472 472 472 LYS LYS A . n A 1 473 ASN 473 473 473 ASN ASN A . n A 1 474 LYS 474 474 474 LYS LYS A . n A 1 475 ILE 475 475 475 ILE ILE A . n A 1 476 LEU 476 476 476 LEU LEU A . n A 1 477 ALA 477 477 477 ALA ALA A . n A 1 478 LYS 478 478 478 LYS LYS A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 LEU 480 480 480 LEU LEU A . n A 1 481 LEU 481 481 481 LEU LEU A . n A 1 482 ASP 482 482 482 ASP ASP A . n A 1 483 LEU 483 483 483 LEU LEU A . n A 1 484 TYR 484 484 484 TYR TYR A . n A 1 485 LYS 485 485 485 LYS LYS A . n A 1 486 THR 486 486 486 THR THR A . n A 1 487 PRO 487 487 487 PRO PRO A . n A 1 488 ASP 488 488 488 ASP ASP A . n A 1 489 ASN 489 489 489 ASN ASN A . n A 1 490 ILE 490 490 490 ILE ILE A . n A 1 491 ASP 491 491 491 ASP ASP A . n A 1 492 ILE 492 492 492 ILE ILE A . n A 1 493 TRP 493 493 493 TRP TRP A . n A 1 494 ILE 494 494 494 ILE ILE A . n A 1 495 GLY 495 495 495 GLY GLY A . n A 1 496 GLY 496 496 496 GLY GLY A . n A 1 497 ASN 497 497 497 ASN ASN A . n A 1 498 ALA 498 498 498 ALA ALA A . n A 1 499 GLU 499 499 499 GLU GLU A . n A 1 500 PRO 500 500 500 PRO PRO A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 VAL 502 502 502 VAL VAL A . n A 1 503 GLU 503 503 503 GLU GLU A . n A 1 504 ARG 504 504 504 ARG ARG A . n A 1 505 GLY 505 505 505 GLY GLY A . n A 1 506 ARG 506 506 506 ARG ARG A . n A 1 507 VAL 507 507 507 VAL VAL A . n A 1 508 GLY 508 508 508 GLY GLY A . n A 1 509 PRO 509 509 509 PRO PRO A . n A 1 510 LEU 510 510 510 LEU LEU A . n A 1 511 LEU 511 511 511 LEU LEU A . n A 1 512 ALA 512 512 512 ALA ALA A . n A 1 513 CYS 513 513 513 CYS CYS A . n A 1 514 LEU 514 514 514 LEU LEU A . n A 1 515 LEU 515 515 515 LEU LEU A . n A 1 516 GLY 516 516 516 GLY GLY A . n A 1 517 ARG 517 517 517 ARG ARG A . n A 1 518 GLN 518 518 518 GLN GLN A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 GLN 520 520 520 GLN GLN A . n A 1 521 GLN 521 521 521 GLN GLN A . n A 1 522 ILE 522 522 522 ILE ILE A . n A 1 523 ARG 523 523 523 ARG ARG A . n A 1 524 ASP 524 524 524 ASP ASP A . n A 1 525 GLY 525 525 525 GLY GLY A . n A 1 526 ASP 526 526 526 ASP ASP A . n A 1 527 ARG 527 527 527 ARG ARG A . n A 1 528 PHE 528 528 528 PHE PHE A . n A 1 529 TRP 529 529 529 TRP TRP A . n A 1 530 TRP 530 530 530 TRP TRP A . n A 1 531 GLU 531 531 531 GLU GLU A . n A 1 532 ASN 532 532 532 ASN ASN A . n A 1 533 PRO 533 533 533 PRO PRO A . n A 1 534 GLY 534 534 534 GLY GLY A . n A 1 535 VAL 535 535 535 VAL VAL A . n A 1 536 PHE 536 536 536 PHE PHE A . n A 1 537 THR 537 537 537 THR THR A . n A 1 538 GLU 538 538 538 GLU GLU A . n A 1 539 LYS 539 539 539 LYS LYS A . n A 1 540 GLN 540 540 540 GLN GLN A . n A 1 541 ARG 541 541 541 ARG ARG A . n A 1 542 ASP 542 542 542 ASP ASP A . n A 1 543 SER 543 543 543 SER SER A . n A 1 544 LEU 544 544 544 LEU LEU A . n A 1 545 GLN 545 545 545 GLN GLN A . n A 1 546 LYS 546 546 546 LYS LYS A . n A 1 547 VAL 547 547 547 VAL VAL A . n A 1 548 SER 548 548 548 SER SER A . n A 1 549 PHE 549 549 549 PHE PHE A . n A 1 550 SER 550 550 550 SER SER A . n A 1 551 ARG 551 551 551 ARG ARG A . n A 1 552 LEU 552 552 552 LEU LEU A . n A 1 553 ILE 553 553 553 ILE ILE A . n A 1 554 CYS 554 554 554 CYS CYS A . n A 1 555 ASP 555 555 555 ASP ASP A . n A 1 556 ASN 556 556 556 ASN ASN A . n A 1 557 THR 557 557 557 THR THR A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ILE 559 559 559 ILE ILE A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LYS 561 561 561 LYS LYS A . n A 1 562 VAL 562 562 562 VAL VAL A . n A 1 563 PRO 563 563 563 PRO PRO A . n A 1 564 LEU 564 564 564 LEU LEU A . n A 1 565 HIS 565 565 565 HIS HIS A . n A 1 566 ALA 566 566 566 ALA ALA A . n A 1 567 PHE 567 567 567 PHE PHE A . n A 1 568 GLN 568 568 568 GLN GLN A . n A 1 569 ALA 569 569 569 ALA ALA A . n A 1 570 ASN 570 570 570 ASN ASN A . n A 1 571 ASN 571 571 571 ASN ASN A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 PRO 573 573 573 PRO PRO A . n A 1 574 HIS 574 574 574 HIS HIS A . n A 1 575 ASP 575 575 575 ASP ASP A . n A 1 576 PHE 576 576 576 PHE PHE A . n A 1 577 VAL 577 577 577 VAL VAL A . n A 1 578 ASP 578 578 578 ASP ASP A . n A 1 579 CYS 579 579 579 CYS CYS A . n A 1 580 SER 580 580 580 SER SER A . n A 1 581 ALA 581 581 581 ALA ALA A . n A 1 582 ILE 582 582 582 ILE ILE A . n A 1 583 ASP 583 583 583 ASP ASP A . n A 1 584 LYS 584 584 584 LYS LYS A . n A 1 585 LEU 585 585 585 LEU LEU A . n A 1 586 ASP 586 586 586 ASP ASP A . n A 1 587 LEU 587 587 587 LEU LEU A . n A 1 588 SER 588 588 588 SER SER A . n A 1 589 PRO 589 589 589 PRO PRO A . n A 1 590 TRP 590 590 590 TRP TRP A . n A 1 591 ALA 591 591 591 ALA ALA A . n A 1 592 SER 592 592 592 SER SER A . n A 1 593 ARG 593 593 593 ARG ARG A . n A 1 594 GLU 594 594 594 GLU GLU A . n A 1 595 ASN 595 595 595 ASN ASN A . n B 1 1 SER 1 1 1 SER SER B . n B 1 2 TRP 2 2 2 TRP TRP B . n B 1 3 GLU 3 3 3 GLU GLU B . n B 1 4 VAL 4 4 4 VAL VAL B . n B 1 5 GLY 5 5 5 GLY GLY B . n B 1 6 CYS 6 6 6 CYS CYS B . n B 1 7 GLY 7 7 7 GLY GLY B . n B 1 8 ALA 8 8 8 ALA ALA B . n B 1 9 PRO 9 9 9 PRO PRO B . n B 1 10 VAL 10 10 10 VAL VAL B . n B 1 11 PRO 11 11 11 PRO PRO B . n B 1 12 LEU 12 12 12 LEU LEU B . n B 1 13 VAL 13 13 13 VAL VAL B . n B 1 14 LYS 14 14 14 LYS LYS B . n B 1 15 CYS 15 15 15 CYS CYS B . n B 1 16 ASP 16 16 16 ASP ASP B . n B 1 17 GLU 17 17 17 GLU GLU B . n B 1 18 ASN 18 18 18 ASN ASN B . n B 1 19 SER 19 19 19 SER SER B . n B 1 20 PRO 20 20 20 PRO PRO B . n B 1 21 TYR 21 21 21 TYR TYR B . n B 1 22 ARG 22 22 22 ARG ARG B . n B 1 23 THR 23 23 23 THR THR B . n B 1 24 ILE 24 24 24 ILE ILE B . n B 1 25 THR 25 25 25 THR THR B . n B 1 26 GLY 26 26 26 GLY GLY B . n B 1 27 ASP 27 27 27 ASP ASP B . n B 1 28 CYS 28 28 28 CYS CYS B . n B 1 29 ASN 29 29 29 ASN ASN B . n B 1 30 ASN 30 30 30 ASN ASN B . n B 1 31 ARG 31 31 31 ARG ARG B . n B 1 32 ARG 32 32 32 ARG ARG B . n B 1 33 SER 33 33 33 SER SER B . n B 1 34 PRO 34 34 34 PRO PRO B . n B 1 35 ALA 35 35 35 ALA ALA B . n B 1 36 LEU 36 36 36 LEU LEU B . n B 1 37 GLY 37 37 37 GLY GLY B . n B 1 38 ALA 38 38 38 ALA ALA B . n B 1 39 ALA 39 39 39 ALA ALA B . n B 1 40 ASN 40 40 40 ASN ASN B . n B 1 41 ARG 41 41 41 ARG ARG B . n B 1 42 ALA 42 42 42 ALA ALA B . n B 1 43 LEU 43 43 43 LEU LEU B . n B 1 44 ALA 44 44 44 ALA ALA B . n B 1 45 ARG 45 45 45 ARG ARG B . n B 1 46 TRP 46 46 46 TRP TRP B . n B 1 47 LEU 47 47 47 LEU LEU B . n B 1 48 PRO 48 48 48 PRO PRO B . n B 1 49 ALA 49 49 49 ALA ALA B . n B 1 50 GLU 50 50 50 GLU GLU B . n B 1 51 TYR 51 51 51 TYR TYR B . n B 1 52 GLU 52 52 52 GLU GLU B . n B 1 53 ASP 53 53 53 ASP ASP B . n B 1 54 GLY 54 54 54 GLY GLY B . n B 1 55 LEU 55 55 55 LEU LEU B . n B 1 56 ALA 56 56 56 ALA ALA B . n B 1 57 VAL 57 57 57 VAL VAL B . n B 1 58 PRO 58 58 58 PRO PRO B . n B 1 59 PHE 59 59 59 PHE PHE B . n B 1 60 GLY 60 60 60 GLY GLY B . n B 1 61 TRP 61 61 61 TRP TRP B . n B 1 62 THR 62 62 62 THR THR B . n B 1 63 GLN 63 63 63 GLN GLN B . n B 1 64 ARG 64 64 64 ARG ARG B . n B 1 65 LYS 65 65 65 LYS LYS B . n B 1 66 THR 66 66 66 THR THR B . n B 1 67 ARG 67 67 67 ARG ARG B . n B 1 68 ASN 68 68 68 ASN ASN B . n B 1 69 GLY 69 69 69 GLY GLY B . n B 1 70 PHE 70 70 70 PHE PHE B . n B 1 71 ARG 71 71 71 ARG ARG B . n B 1 72 VAL 72 72 72 VAL VAL B . n B 1 73 PRO 73 73 73 PRO PRO B . n B 1 74 LEU 74 74 74 LEU LEU B . n B 1 75 ALA 75 75 75 ALA ALA B . n B 1 76 ARG 76 76 76 ARG ARG B . n B 1 77 GLU 77 77 77 GLU GLU B . n B 1 78 VAL 78 78 78 VAL VAL B . n B 1 79 SER 79 79 79 SER SER B . n B 1 80 ASN 80 80 80 ASN ASN B . n B 1 81 LYS 81 81 81 LYS LYS B . n B 1 82 ILE 82 82 82 ILE ILE B . n B 1 83 VAL 83 83 83 VAL VAL B . n B 1 84 GLY 84 84 84 GLY GLY B . n B 1 85 TYR 85 85 85 TYR TYR B . n B 1 86 LEU 86 86 86 LEU LEU B . n B 1 87 ASP 87 87 87 ASP ASP B . n B 1 88 GLU 88 88 88 GLU GLU B . n B 1 89 GLU 89 89 89 GLU GLU B . n B 1 90 GLY 90 90 90 GLY GLY B . n B 1 91 VAL 91 91 91 VAL VAL B . n B 1 92 LEU 92 92 92 LEU LEU B . n B 1 93 ASP 93 93 93 ASP ASP B . n B 1 94 GLN 94 94 94 GLN GLN B . n B 1 95 ASN 95 95 95 ASN ASN B . n B 1 96 ARG 96 96 96 ARG ARG B . n B 1 97 SER 97 97 97 SER SER B . n B 1 98 LEU 98 98 98 LEU LEU B . n B 1 99 LEU 99 99 99 LEU LEU B . n B 1 100 PHE 100 100 100 PHE PHE B . n B 1 101 MET 101 101 101 MET MET B . n B 1 102 GLN 102 102 102 GLN GLN B . n B 1 103 TRP 103 103 103 TRP TRP B . n B 1 104 GLY 104 104 104 GLY GLY B . n B 1 105 GLN 105 105 105 GLN GLN B . n B 1 106 ILE 106 106 106 ILE ILE B . n B 1 107 VAL 107 107 107 VAL VAL B . n B 1 108 ASP 108 108 108 ASP ASP B . n B 1 109 HIS 109 109 109 HIS HIS B . n B 1 110 ASP 110 110 110 ASP ASP B . n B 1 111 LEU 111 111 111 LEU LEU B . n B 1 112 ASP 112 112 112 ASP ASP B . n B 1 113 PHE 113 113 113 PHE PHE B . n B 1 114 ALA 114 114 114 ALA ALA B . n B 1 115 PRO 115 115 115 PRO PRO B . n B 1 116 GLU 116 116 116 GLU GLU B . n B 1 117 THR 117 117 117 THR THR B . n B 1 118 GLU 118 118 118 GLU GLU B . n B 1 119 LEU 119 119 119 LEU LEU B . n B 1 120 GLY 120 120 120 GLY GLY B . n B 1 121 SER 121 121 121 SER SER B . n B 1 122 SER 122 122 122 SER SER B . n B 1 123 GLU 123 123 123 GLU GLU B . n B 1 124 HIS 124 124 124 HIS HIS B . n B 1 125 SER 125 125 125 SER SER B . n B 1 126 LYS 126 126 126 LYS LYS B . n B 1 127 VAL 127 127 127 VAL VAL B . n B 1 128 GLN 128 128 128 GLN GLN B . n B 1 129 CYS 129 129 129 CYS CYS B . n B 1 130 GLU 130 130 130 GLU GLU B . n B 1 131 GLU 131 131 131 GLU GLU B . n B 1 132 TYR 132 132 132 TYR TYR B . n B 1 133 CYS 133 133 133 CYS CYS B . n B 1 134 ILE 134 134 134 ILE ILE B . n B 1 135 GLN 135 135 135 GLN GLN B . n B 1 136 GLY 136 136 136 GLY GLY B . n B 1 137 ASP 137 137 137 ASP ASP B . n B 1 138 ASN 138 138 138 ASN ASN B . n B 1 139 CYS 139 139 139 CYS CYS B . n B 1 140 PHE 140 140 140 PHE PHE B . n B 1 141 PRO 141 141 141 PRO PRO B . n B 1 142 ILE 142 142 142 ILE ILE B . n B 1 143 MET 143 143 143 MET MET B . n B 1 144 PHE 144 144 144 PHE PHE B . n B 1 145 PRO 145 145 145 PRO PRO B . n B 1 146 LYS 146 146 146 LYS LYS B . n B 1 147 ASN 147 147 147 ASN ASN B . n B 1 148 ASP 148 148 148 ASP ASP B . n B 1 149 PRO 149 149 149 PRO PRO B . n B 1 150 LYS 150 150 150 LYS LYS B . n B 1 151 LEU 151 151 151 LEU LEU B . n B 1 152 LYS 152 152 152 LYS LYS B . n B 1 153 THR 153 153 153 THR THR B . n B 1 154 GLN 154 154 154 GLN GLN B . n B 1 155 GLY 155 155 155 GLY GLY B . n B 1 156 LYS 156 156 156 LYS LYS B . n B 1 157 CYS 157 157 157 CYS CYS B . n B 1 158 MET 158 158 158 MET MET B . n B 1 159 PRO 159 159 159 PRO PRO B . n B 1 160 PHE 160 160 160 PHE PHE B . n B 1 161 PHE 161 161 161 PHE PHE B . n B 1 162 ARG 162 162 162 ARG ARG B . n B 1 163 ALA 163 163 163 ALA ALA B . n B 1 164 GLY 164 164 164 GLY GLY B . n B 1 165 PHE 165 165 165 PHE PHE B . n B 1 166 VAL 166 166 166 VAL VAL B . n B 1 167 CYS 167 167 167 CYS CYS B . n B 1 168 PRO 168 168 168 PRO PRO B . n B 1 169 THR 169 169 169 THR THR B . n B 1 170 PRO 170 170 170 PRO PRO B . n B 1 171 PRO 171 171 171 PRO PRO B . n B 1 172 TYR 172 172 172 TYR TYR B . n B 1 173 GLN 173 173 173 GLN GLN B . n B 1 174 SER 174 174 174 SER SER B . n B 1 175 LEU 175 175 175 LEU LEU B . n B 1 176 ALA 176 176 176 ALA ALA B . n B 1 177 ARG 177 177 177 ARG ARG B . n B 1 178 ASP 178 178 178 ASP ASP B . n B 1 179 GLN 179 179 179 GLN GLN B . n B 1 180 ILE 180 180 180 ILE ILE B . n B 1 181 ASN 181 181 181 ASN ASN B . n B 1 182 SER 182 182 182 SER SER B . n B 1 183 VAL 183 183 183 VAL VAL B . n B 1 184 THR 184 184 184 THR THR B . n B 1 185 SER 185 185 185 SER SER B . n B 1 186 PHE 186 186 186 PHE PHE B . n B 1 187 LEU 187 187 187 LEU LEU B . n B 1 188 ASP 188 188 188 ASP ASP B . n B 1 189 ALA 189 189 189 ALA ALA B . n B 1 190 SER 190 190 190 SER SER B . n B 1 191 LEU 191 191 191 LEU LEU B . n B 1 192 VAL 192 192 192 VAL VAL B . n B 1 193 TYR 193 193 193 TYR TYR B . n B 1 194 GLY 194 194 194 GLY GLY B . n B 1 195 SER 195 195 195 SER SER B . n B 1 196 GLU 196 196 196 GLU GLU B . n B 1 197 PRO 197 197 197 PRO PRO B . n B 1 198 SER 198 198 198 SER SER B . n B 1 199 LEU 199 199 199 LEU LEU B . n B 1 200 ALA 200 200 200 ALA ALA B . n B 1 201 SER 201 201 201 SER SER B . n B 1 202 ARG 202 202 202 ARG ARG B . n B 1 203 LEU 203 203 203 LEU LEU B . n B 1 204 ARG 204 204 204 ARG ARG B . n B 1 205 ASN 205 205 205 ASN ASN B . n B 1 206 LEU 206 206 206 LEU LEU B . n B 1 207 SER 207 207 207 SER SER B . n B 1 208 SER 208 208 208 SER SER B . n B 1 209 PRO 209 209 209 PRO PRO B . n B 1 210 LEU 210 210 210 LEU LEU B . n B 1 211 GLY 211 211 211 GLY GLY B . n B 1 212 LEU 212 212 212 LEU LEU B . n B 1 213 MET 213 213 213 MET MET B . n B 1 214 ALA 214 214 214 ALA ALA B . n B 1 215 VAL 215 215 215 VAL VAL B . n B 1 216 ASN 216 216 216 ASN ASN B . n B 1 217 GLN 217 217 217 GLN GLN B . n B 1 218 GLU 218 218 218 GLU GLU B . n B 1 219 ALA 219 219 219 ALA ALA B . n B 1 220 TRP 220 220 220 TRP TRP B . n B 1 221 ASP 221 221 221 ASP ASP B . n B 1 222 HIS 222 222 222 HIS HIS B . n B 1 223 GLY 223 223 223 GLY GLY B . n B 1 224 LEU 224 224 224 LEU LEU B . n B 1 225 ALA 225 225 225 ALA ALA B . n B 1 226 TYR 226 226 226 TYR TYR B . n B 1 227 PRO 227 227 227 PRO PRO B . n B 1 228 PRO 228 228 228 PRO PRO B . n B 1 229 PHE 229 229 229 PHE PHE B . n B 1 230 ASN 230 230 230 ASN ASN B . n B 1 231 ASN 231 231 231 ASN ASN B . n B 1 232 MET 232 232 232 MET MET B . n B 1 233 LYS 233 233 233 LYS LYS B . n B 1 234 PRO 234 234 234 PRO PRO B . n B 1 235 SER 235 235 235 SER SER B . n B 1 236 PRO 236 236 236 PRO PRO B . n B 1 237 CYS 237 237 237 CYS CYS B . n B 1 238 GLU 238 238 238 GLU GLU B . n B 1 239 PHE 239 239 239 PHE PHE B . n B 1 240 ILE 240 240 240 ILE ILE B . n B 1 241 ASN 241 241 241 ASN ASN B . n B 1 242 THR 242 242 242 THR THR B . n B 1 243 THR 243 243 243 THR THR B . n B 1 244 ALA 244 244 244 ALA ALA B . n B 1 245 ARG 245 245 245 ARG ARG B . n B 1 246 VAL 246 246 246 VAL VAL B . n B 1 247 PRO 247 247 247 PRO PRO B . n B 1 248 CYS 248 248 248 CYS CYS B . n B 1 249 PHE 249 249 249 PHE PHE B . n B 1 250 GLN 250 250 250 GLN GLN B . n B 1 251 ALA 251 251 251 ALA ALA B . n B 1 252 GLY 252 252 252 GLY GLY B . n B 1 253 ASP 253 253 253 ASP ASP B . n B 1 254 SER 254 254 254 SER SER B . n B 1 255 ARG 255 255 255 ARG ARG B . n B 1 256 ALA 256 256 256 ALA ALA B . n B 1 257 SER 257 257 257 SER SER B . n B 1 258 GLU 258 258 258 GLU GLU B . n B 1 259 GLN 259 259 259 GLN GLN B . n B 1 260 ILE 260 260 260 ILE ILE B . n B 1 261 LEU 261 261 261 LEU LEU B . n B 1 262 LEU 262 262 262 LEU LEU B . n B 1 263 ALA 263 263 263 ALA ALA B . n B 1 264 THR 264 264 264 THR THR B . n B 1 265 VAL 265 265 265 VAL VAL B . n B 1 266 HIS 266 266 266 HIS HIS B . n B 1 267 THR 267 267 267 THR THR B . n B 1 268 LEU 268 268 268 LEU LEU B . n B 1 269 LEU 269 269 269 LEU LEU B . n B 1 270 LEU 270 270 270 LEU LEU B . n B 1 271 ARG 271 271 271 ARG ARG B . n B 1 272 GLU 272 272 272 GLU GLU B . n B 1 273 HIS 273 273 273 HIS HIS B . n B 1 274 ASN 274 274 274 ASN ASN B . n B 1 275 ARG 275 275 275 ARG ARG B . n B 1 276 LEU 276 276 276 LEU LEU B . n B 1 277 ALA 277 277 277 ALA ALA B . n B 1 278 ARG 278 278 278 ARG ARG B . n B 1 279 GLU 279 279 279 GLU GLU B . n B 1 280 LEU 280 280 280 LEU LEU B . n B 1 281 LYS 281 281 281 LYS LYS B . n B 1 282 ARG 282 282 282 ARG ARG B . n B 1 283 LEU 283 283 283 LEU LEU B . n B 1 284 ASN 284 284 284 ASN ASN B . n B 1 285 PRO 285 285 285 PRO PRO B . n B 1 286 HIS 286 286 286 HIS HIS B . n B 1 287 TRP 287 287 287 TRP TRP B . n B 1 288 ASP 288 288 288 ASP ASP B . n B 1 289 GLY 289 289 289 GLY GLY B . n B 1 290 GLU 290 290 290 GLU GLU B . n B 1 291 LYS 291 291 291 LYS LYS B . n B 1 292 LEU 292 292 292 LEU LEU B . n B 1 293 TYR 293 293 293 TYR TYR B . n B 1 294 GLN 294 294 294 GLN GLN B . n B 1 295 GLU 295 295 295 GLU GLU B . n B 1 296 ALA 296 296 296 ALA ALA B . n B 1 297 ARG 297 297 297 ARG ARG B . n B 1 298 LYS 298 298 298 LYS LYS B . n B 1 299 ILE 299 299 299 ILE ILE B . n B 1 300 LEU 300 300 300 LEU LEU B . n B 1 301 GLY 301 301 301 GLY GLY B . n B 1 302 ALA 302 302 302 ALA ALA B . n B 1 303 PHE 303 303 303 PHE PHE B . n B 1 304 ILE 304 304 304 ILE ILE B . n B 1 305 GLN 305 305 305 GLN GLN B . n B 1 306 ILE 306 306 306 ILE ILE B . n B 1 307 ILE 307 307 307 ILE ILE B . n B 1 308 THR 308 308 308 THR THR B . n B 1 309 PHE 309 309 309 PHE PHE B . n B 1 310 ARG 310 310 310 ARG ARG B . n B 1 311 ASP 311 311 311 ASP ASP B . n B 1 312 TYR 312 312 312 TYR TYR B . n B 1 313 LEU 313 313 313 LEU LEU B . n B 1 314 PRO 314 314 314 PRO PRO B . n B 1 315 ILE 315 315 315 ILE ILE B . n B 1 316 VAL 316 316 316 VAL VAL B . n B 1 317 LEU 317 317 317 LEU LEU B . n B 1 318 GLY 318 318 318 GLY GLY B . n B 1 319 SER 319 319 319 SER SER B . n B 1 320 GLU 320 320 320 GLU GLU B . n B 1 321 MET 321 321 321 MET MET B . n B 1 322 GLN 322 322 322 GLN GLN B . n B 1 323 LYS 323 323 323 LYS LYS B . n B 1 324 TRP 324 324 324 TRP TRP B . n B 1 325 ILE 325 325 325 ILE ILE B . n B 1 326 PRO 326 326 326 PRO PRO B . n B 1 327 ARG 327 327 327 ARG ARG B . n B 1 328 TYR 328 328 328 TYR TYR B . n B 1 329 GLN 329 329 329 GLN GLN B . n B 1 330 GLY 330 330 330 GLY GLY B . n B 1 331 TYR 331 331 331 TYR TYR B . n B 1 332 ASN 332 332 332 ASN ASN B . n B 1 333 ASN 333 333 333 ASN ASN B . n B 1 334 SER 334 334 334 SER SER B . n B 1 335 VAL 335 335 335 VAL VAL B . n B 1 336 ASP 336 336 336 ASP ASP B . n B 1 337 PRO 337 337 337 PRO PRO B . n B 1 338 ARG 338 338 338 ARG ARG B . n B 1 339 ILE 339 339 339 ILE ILE B . n B 1 340 SER 340 340 340 SER SER B . n B 1 341 ASN 341 341 341 ASN ASN B . n B 1 342 VAL 342 342 342 VAL VAL B . n B 1 343 PHE 343 343 343 PHE PHE B . n B 1 344 THR 344 344 344 THR THR B . n B 1 345 PHE 345 345 345 PHE PHE B . n B 1 346 ALA 346 346 346 ALA ALA B . n B 1 347 PHE 347 347 347 PHE PHE B . n B 1 348 ARG 348 348 348 ARG ARG B . n B 1 349 PHE 349 349 349 PHE PHE B . n B 1 350 GLY 350 350 350 GLY GLY B . n B 1 351 HIS 351 351 351 HIS HIS B . n B 1 352 MET 352 352 352 MET MET B . n B 1 353 GLU 353 353 353 GLU GLU B . n B 1 354 VAL 354 354 354 VAL VAL B . n B 1 355 PRO 355 355 355 PRO PRO B . n B 1 356 SER 356 356 356 SER SER B . n B 1 357 THR 357 357 357 THR THR B . n B 1 358 VAL 358 358 358 VAL VAL B . n B 1 359 SER 359 359 359 SER SER B . n B 1 360 ARG 360 360 360 ARG ARG B . n B 1 361 LEU 361 361 361 LEU LEU B . n B 1 362 ASP 362 362 362 ASP ASP B . n B 1 363 GLU 363 363 363 GLU GLU B . n B 1 364 ASN 364 364 364 ASN ASN B . n B 1 365 TYR 365 365 365 TYR TYR B . n B 1 366 GLN 366 366 366 GLN GLN B . n B 1 367 PRO 367 367 367 PRO PRO B . n B 1 368 ARG 368 368 368 ARG ARG B . n B 1 369 GLY 369 369 369 GLY GLY B . n B 1 370 PRO 370 370 370 PRO PRO B . n B 1 371 GLU 371 371 371 GLU GLU B . n B 1 372 ALA 372 372 372 ALA ALA B . n B 1 373 GLU 373 373 373 GLU GLU B . n B 1 374 LEU 374 374 374 LEU LEU B . n B 1 375 PRO 375 375 375 PRO PRO B . n B 1 376 LEU 376 376 376 LEU LEU B . n B 1 377 HIS 377 377 377 HIS HIS B . n B 1 378 THR 378 378 378 THR THR B . n B 1 379 LEU 379 379 379 LEU LEU B . n B 1 380 PHE 380 380 380 PHE PHE B . n B 1 381 PHE 381 381 381 PHE PHE B . n B 1 382 ASN 382 382 382 ASN ASN B . n B 1 383 THR 383 383 383 THR THR B . n B 1 384 TRP 384 384 384 TRP TRP B . n B 1 385 ARG 385 385 385 ARG ARG B . n B 1 386 ILE 386 386 386 ILE ILE B . n B 1 387 ILE 387 387 387 ILE ILE B . n B 1 388 LYS 388 388 388 LYS LYS B . n B 1 389 ASP 389 389 389 ASP ASP B . n B 1 390 GLY 390 390 390 GLY GLY B . n B 1 391 GLY 391 391 391 GLY GLY B . n B 1 392 ILE 392 392 392 ILE ILE B . n B 1 393 ASP 393 393 393 ASP ASP B . n B 1 394 PRO 394 394 394 PRO PRO B . n B 1 395 LEU 395 395 395 LEU LEU B . n B 1 396 VAL 396 396 396 VAL VAL B . n B 1 397 ARG 397 397 397 ARG ARG B . n B 1 398 GLY 398 398 398 GLY GLY B . n B 1 399 LEU 399 399 399 LEU LEU B . n B 1 400 LEU 400 400 400 LEU LEU B . n B 1 401 ALA 401 401 401 ALA ALA B . n B 1 402 LYS 402 402 402 LYS LYS B . n B 1 403 LYS 403 403 403 LYS LYS B . n B 1 404 SER 404 404 404 SER SER B . n B 1 405 LYS 405 405 405 LYS LYS B . n B 1 406 LEU 406 406 406 LEU LEU B . n B 1 407 MET 407 407 407 MET MET B . n B 1 408 ASN 408 408 408 ASN ASN B . n B 1 409 GLN 409 409 409 GLN GLN B . n B 1 410 ASN 410 410 410 ASN ASN B . n B 1 411 LYS 411 411 411 LYS LYS B . n B 1 412 MET 412 412 412 MET MET B . n B 1 413 VAL 413 413 413 VAL VAL B . n B 1 414 THR 414 414 414 THR THR B . n B 1 415 SER 415 415 415 SER SER B . n B 1 416 GLU 416 416 416 GLU GLU B . n B 1 417 LEU 417 417 417 LEU LEU B . n B 1 418 ARG 418 418 418 ARG ARG B . n B 1 419 ASN 419 419 419 ASN ASN B . n B 1 420 LYS 420 420 420 LYS LYS B . n B 1 421 LEU 421 421 421 LEU LEU B . n B 1 422 PHE 422 422 422 PHE PHE B . n B 1 423 GLN 423 423 423 GLN GLN B . n B 1 424 PRO 424 424 424 PRO PRO B . n B 1 425 THR 425 425 425 THR THR B . n B 1 426 HIS 426 426 426 HIS HIS B . n B 1 427 LYS 427 427 427 LYS LYS B . n B 1 428 ILE 428 428 428 ILE ILE B . n B 1 429 HIS 429 429 429 HIS HIS B . n B 1 430 GLY 430 430 430 GLY GLY B . n B 1 431 PHE 431 431 431 PHE PHE B . n B 1 432 ASP 432 432 432 ASP ASP B . n B 1 433 LEU 433 433 433 LEU LEU B . n B 1 434 ALA 434 434 434 ALA ALA B . n B 1 435 ALA 435 435 435 ALA ALA B . n B 1 436 ILE 436 436 436 ILE ILE B . n B 1 437 ASN 437 437 437 ASN ASN B . n B 1 438 LEU 438 438 438 LEU LEU B . n B 1 439 GLN 439 439 439 GLN GLN B . n B 1 440 ARG 440 440 440 ARG ARG B . n B 1 441 CYS 441 441 441 CYS CYS B . n B 1 442 ARG 442 442 442 ARG ARG B . n B 1 443 ASP 443 443 443 ASP ASP B . n B 1 444 HIS 444 444 444 HIS HIS B . n B 1 445 GLY 445 445 445 GLY GLY B . n B 1 446 MET 446 446 446 MET MET B . n B 1 447 PRO 447 447 447 PRO PRO B . n B 1 448 GLY 448 448 448 GLY GLY B . n B 1 449 TYR 449 449 449 TYR TYR B . n B 1 450 ASN 450 450 450 ASN ASN B . n B 1 451 SER 451 451 451 SER SER B . n B 1 452 TRP 452 452 452 TRP TRP B . n B 1 453 ARG 453 453 453 ARG ARG B . n B 1 454 GLY 454 454 454 GLY GLY B . n B 1 455 PHE 455 455 455 PHE PHE B . n B 1 456 CYS 456 456 456 CYS CYS B . n B 1 457 GLY 457 457 457 GLY GLY B . n B 1 458 LEU 458 458 458 LEU LEU B . n B 1 459 SER 459 459 459 SER SER B . n B 1 460 GLN 460 460 460 GLN GLN B . n B 1 461 PRO 461 461 461 PRO PRO B . n B 1 462 LYS 462 462 462 LYS LYS B . n B 1 463 THR 463 463 463 THR THR B . n B 1 464 LEU 464 464 464 LEU LEU B . n B 1 465 LYS 465 465 465 LYS LYS B . n B 1 466 GLY 466 466 466 GLY GLY B . n B 1 467 LEU 467 467 467 LEU LEU B . n B 1 468 GLN 468 468 468 GLN GLN B . n B 1 469 ALA 469 469 469 ALA ALA B . n B 1 470 VAL 470 470 470 VAL VAL B . n B 1 471 LEU 471 471 471 LEU LEU B . n B 1 472 LYS 472 472 472 LYS LYS B . n B 1 473 ASN 473 473 473 ASN ASN B . n B 1 474 LYS 474 474 474 LYS LYS B . n B 1 475 ILE 475 475 475 ILE ILE B . n B 1 476 LEU 476 476 476 LEU LEU B . n B 1 477 ALA 477 477 477 ALA ALA B . n B 1 478 LYS 478 478 478 LYS LYS B . n B 1 479 LYS 479 479 479 LYS LYS B . n B 1 480 LEU 480 480 480 LEU LEU B . n B 1 481 LEU 481 481 481 LEU LEU B . n B 1 482 ASP 482 482 482 ASP ASP B . n B 1 483 LEU 483 483 483 LEU LEU B . n B 1 484 TYR 484 484 484 TYR TYR B . n B 1 485 LYS 485 485 485 LYS LYS B . n B 1 486 THR 486 486 486 THR THR B . n B 1 487 PRO 487 487 487 PRO PRO B . n B 1 488 ASP 488 488 488 ASP ASP B . n B 1 489 ASN 489 489 489 ASN ASN B . n B 1 490 ILE 490 490 490 ILE ILE B . n B 1 491 ASP 491 491 491 ASP ASP B . n B 1 492 ILE 492 492 492 ILE ILE B . n B 1 493 TRP 493 493 493 TRP TRP B . n B 1 494 ILE 494 494 494 ILE ILE B . n B 1 495 GLY 495 495 495 GLY GLY B . n B 1 496 GLY 496 496 496 GLY GLY B . n B 1 497 ASN 497 497 497 ASN ASN B . n B 1 498 ALA 498 498 498 ALA ALA B . n B 1 499 GLU 499 499 499 GLU GLU B . n B 1 500 PRO 500 500 500 PRO PRO B . n B 1 501 MET 501 501 501 MET MET B . n B 1 502 VAL 502 502 502 VAL VAL B . n B 1 503 GLU 503 503 503 GLU GLU B . n B 1 504 ARG 504 504 504 ARG ARG B . n B 1 505 GLY 505 505 505 GLY GLY B . n B 1 506 ARG 506 506 506 ARG ARG B . n B 1 507 VAL 507 507 507 VAL VAL B . n B 1 508 GLY 508 508 508 GLY GLY B . n B 1 509 PRO 509 509 509 PRO PRO B . n B 1 510 LEU 510 510 510 LEU LEU B . n B 1 511 LEU 511 511 511 LEU LEU B . n B 1 512 ALA 512 512 512 ALA ALA B . n B 1 513 CYS 513 513 513 CYS CYS B . n B 1 514 LEU 514 514 514 LEU LEU B . n B 1 515 LEU 515 515 515 LEU LEU B . n B 1 516 GLY 516 516 516 GLY GLY B . n B 1 517 ARG 517 517 517 ARG ARG B . n B 1 518 GLN 518 518 518 GLN GLN B . n B 1 519 PHE 519 519 519 PHE PHE B . n B 1 520 GLN 520 520 520 GLN GLN B . n B 1 521 GLN 521 521 521 GLN GLN B . n B 1 522 ILE 522 522 522 ILE ILE B . n B 1 523 ARG 523 523 523 ARG ARG B . n B 1 524 ASP 524 524 524 ASP ASP B . n B 1 525 GLY 525 525 525 GLY GLY B . n B 1 526 ASP 526 526 526 ASP ASP B . n B 1 527 ARG 527 527 527 ARG ARG B . n B 1 528 PHE 528 528 528 PHE PHE B . n B 1 529 TRP 529 529 529 TRP TRP B . n B 1 530 TRP 530 530 530 TRP TRP B . n B 1 531 GLU 531 531 531 GLU GLU B . n B 1 532 ASN 532 532 532 ASN ASN B . n B 1 533 PRO 533 533 533 PRO PRO B . n B 1 534 GLY 534 534 534 GLY GLY B . n B 1 535 VAL 535 535 535 VAL VAL B . n B 1 536 PHE 536 536 536 PHE PHE B . n B 1 537 THR 537 537 537 THR THR B . n B 1 538 GLU 538 538 538 GLU GLU B . n B 1 539 LYS 539 539 539 LYS LYS B . n B 1 540 GLN 540 540 540 GLN GLN B . n B 1 541 ARG 541 541 541 ARG ARG B . n B 1 542 ASP 542 542 542 ASP ASP B . n B 1 543 SER 543 543 543 SER SER B . n B 1 544 LEU 544 544 544 LEU LEU B . n B 1 545 GLN 545 545 545 GLN GLN B . n B 1 546 LYS 546 546 546 LYS LYS B . n B 1 547 VAL 547 547 547 VAL VAL B . n B 1 548 SER 548 548 548 SER SER B . n B 1 549 PHE 549 549 549 PHE PHE B . n B 1 550 SER 550 550 550 SER SER B . n B 1 551 ARG 551 551 551 ARG ARG B . n B 1 552 LEU 552 552 552 LEU LEU B . n B 1 553 ILE 553 553 553 ILE ILE B . n B 1 554 CYS 554 554 554 CYS CYS B . n B 1 555 ASP 555 555 555 ASP ASP B . n B 1 556 ASN 556 556 556 ASN ASN B . n B 1 557 THR 557 557 557 THR THR B . n B 1 558 HIS 558 558 558 HIS HIS B . n B 1 559 ILE 559 559 559 ILE ILE B . n B 1 560 THR 560 560 560 THR THR B . n B 1 561 LYS 561 561 561 LYS LYS B . n B 1 562 VAL 562 562 562 VAL VAL B . n B 1 563 PRO 563 563 563 PRO PRO B . n B 1 564 LEU 564 564 564 LEU LEU B . n B 1 565 HIS 565 565 565 HIS HIS B . n B 1 566 ALA 566 566 566 ALA ALA B . n B 1 567 PHE 567 567 567 PHE PHE B . n B 1 568 GLN 568 568 568 GLN GLN B . n B 1 569 ALA 569 569 569 ALA ALA B . n B 1 570 ASN 570 570 570 ASN ASN B . n B 1 571 ASN 571 571 571 ASN ASN B . n B 1 572 TYR 572 572 572 TYR TYR B . n B 1 573 PRO 573 573 573 PRO PRO B . n B 1 574 HIS 574 574 574 HIS HIS B . n B 1 575 ASP 575 575 575 ASP ASP B . n B 1 576 PHE 576 576 576 PHE PHE B . n B 1 577 VAL 577 577 577 VAL VAL B . n B 1 578 ASP 578 578 578 ASP ASP B . n B 1 579 CYS 579 579 579 CYS CYS B . n B 1 580 SER 580 580 580 SER SER B . n B 1 581 ALA 581 581 581 ALA ALA B . n B 1 582 ILE 582 582 582 ILE ILE B . n B 1 583 ASP 583 583 583 ASP ASP B . n B 1 584 LYS 584 584 584 LYS LYS B . n B 1 585 LEU 585 585 585 LEU LEU B . n B 1 586 ASP 586 586 586 ASP ASP B . n B 1 587 LEU 587 587 587 LEU LEU B . n B 1 588 SER 588 588 588 SER SER B . n B 1 589 PRO 589 589 589 PRO PRO B . n B 1 590 TRP 590 590 590 TRP TRP B . n B 1 591 ALA 591 591 591 ALA ALA B . n B 1 592 SER 592 592 592 SER SER B . n B 1 593 ARG 593 593 593 ARG ARG B . n B 1 594 GLU 594 594 594 GLU GLU B . n B 1 595 ASN 595 595 595 ASN ASN B . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code C 2 NAG 1 596 1 NAG NAG A . D 2 NAG 2 597 2 NAG NAG A . E 2 NAG 1 598 3 NAG NAG A . F 2 NAG 2 599 4 NAG NAG A . G 2 NAG 1 600 5 NAG NAG A . H 2 NAG 2 601 6 NAG NAG A . I 3 MAN 3 602 7 MAN MAN A . J 2 NAG 1 603 8 NAG NAG A . K 4 CA 1 1001 1001 CA CA A . L 5 CO3 1 2001 2001 CO3 CO3 A . M 6 HEM 1 605 605 HEM HEM A . N 7 FMT 1 3001 3001 FMT FMT A . O 7 FMT 1 3002 3002 FMT FMT A . P 7 FMT 1 3003 3003 FMT FMT A . Q 2 NAG 1 596 1 NAG NAG B . R 2 NAG 2 597 2 NAG NAG B . S 2 NAG 1 598 3 NAG NAG B . T 2 NAG 2 599 4 NAG NAG B . U 2 NAG 1 600 5 NAG NAG B . V 2 NAG 2 601 6 NAG NAG B . W 3 MAN 3 602 7 MAN MAN B . X 2 NAG 1 603 8 NAG NAG B . Y 4 CA 1 1002 1002 CA CA B . Z 5 CO3 1 2002 2002 CO3 CO3 B . AA 6 HEM 1 605 605 HEM HEM B . BA 7 FMT 1 3004 3004 FMT FMT B . CA 7 FMT 1 3005 3005 FMT FMT B . DA 7 FMT 1 3006 3006 FMT FMT B . EA 8 HOH 1 3004 2 HOH HOH A . EA 8 HOH 2 3005 3 HOH HOH A . EA 8 HOH 3 3006 5 HOH HOH A . EA 8 HOH 4 3007 8 HOH HOH A . EA 8 HOH 5 3008 9 HOH HOH A . EA 8 HOH 6 3009 11 HOH HOH A . EA 8 HOH 7 3010 12 HOH HOH A . EA 8 HOH 8 3011 14 HOH HOH A . EA 8 HOH 9 3012 15 HOH HOH A . EA 8 HOH 10 3013 17 HOH HOH A . EA 8 HOH 11 3014 20 HOH HOH A . EA 8 HOH 12 3015 22 HOH HOH A . EA 8 HOH 13 3016 23 HOH HOH A . EA 8 HOH 14 3017 24 HOH HOH A . EA 8 HOH 15 3018 25 HOH HOH A . EA 8 HOH 16 3019 26 HOH HOH A . EA 8 HOH 17 3020 27 HOH HOH A . EA 8 HOH 18 3021 32 HOH HOH A . EA 8 HOH 19 3022 35 HOH HOH A . EA 8 HOH 20 3023 36 HOH HOH A . EA 8 HOH 21 3024 37 HOH HOH A . EA 8 HOH 22 3025 39 HOH HOH A . EA 8 HOH 23 3026 40 HOH HOH A . EA 8 HOH 24 3027 45 HOH HOH A . EA 8 HOH 25 3028 47 HOH HOH A . EA 8 HOH 26 3029 48 HOH HOH A . EA 8 HOH 27 3030 49 HOH HOH A . EA 8 HOH 28 3031 50 HOH HOH A . EA 8 HOH 29 3032 51 HOH HOH A . EA 8 HOH 30 3033 54 HOH HOH A . EA 8 HOH 31 3034 55 HOH HOH A . EA 8 HOH 32 3035 56 HOH HOH A . EA 8 HOH 33 3036 57 HOH HOH A . EA 8 HOH 34 3037 58 HOH HOH A . EA 8 HOH 35 3038 60 HOH HOH A . EA 8 HOH 36 3039 61 HOH HOH A . EA 8 HOH 37 3040 62 HOH HOH A . EA 8 HOH 38 3041 65 HOH HOH A . EA 8 HOH 39 3042 66 HOH HOH A . EA 8 HOH 40 3043 67 HOH HOH A . EA 8 HOH 41 3044 69 HOH HOH A . EA 8 HOH 42 3045 72 HOH HOH A . EA 8 HOH 43 3046 75 HOH HOH A . EA 8 HOH 44 3047 76 HOH HOH A . EA 8 HOH 45 3048 77 HOH HOH A . EA 8 HOH 46 3049 78 HOH HOH A . EA 8 HOH 47 3050 79 HOH HOH A . EA 8 HOH 48 3051 80 HOH HOH A . EA 8 HOH 49 3052 81 HOH HOH A . EA 8 HOH 50 3053 82 HOH HOH A . EA 8 HOH 51 3054 83 HOH HOH A . EA 8 HOH 52 3055 84 HOH HOH A . EA 8 HOH 53 3056 85 HOH HOH A . EA 8 HOH 54 3057 86 HOH HOH A . EA 8 HOH 55 3058 87 HOH HOH A . EA 8 HOH 56 3059 94 HOH HOH A . EA 8 HOH 57 3060 107 HOH HOH A . EA 8 HOH 58 3061 108 HOH HOH A . EA 8 HOH 59 3062 109 HOH HOH A . EA 8 HOH 60 3063 110 HOH HOH A . EA 8 HOH 61 3064 111 HOH HOH A . EA 8 HOH 62 3065 112 HOH HOH A . EA 8 HOH 63 3066 113 HOH HOH A . EA 8 HOH 64 3067 114 HOH HOH A . EA 8 HOH 65 3068 115 HOH HOH A . EA 8 HOH 66 3069 116 HOH HOH A . EA 8 HOH 67 3070 117 HOH HOH A . EA 8 HOH 68 3071 118 HOH HOH A . EA 8 HOH 69 3072 119 HOH HOH A . EA 8 HOH 70 3073 120 HOH HOH A . EA 8 HOH 71 3074 121 HOH HOH A . EA 8 HOH 72 3075 122 HOH HOH A . EA 8 HOH 73 3076 123 HOH HOH A . EA 8 HOH 74 3077 124 HOH HOH A . EA 8 HOH 75 3078 125 HOH HOH A . EA 8 HOH 76 3079 126 HOH HOH A . EA 8 HOH 77 3080 127 HOH HOH A . EA 8 HOH 78 3081 128 HOH HOH A . EA 8 HOH 79 3082 129 HOH HOH A . EA 8 HOH 80 3083 130 HOH HOH A . EA 8 HOH 81 3084 131 HOH HOH A . EA 8 HOH 82 3085 132 HOH HOH A . EA 8 HOH 83 3086 133 HOH HOH A . EA 8 HOH 84 3087 134 HOH HOH A . EA 8 HOH 85 3088 135 HOH HOH A . EA 8 HOH 86 3089 136 HOH HOH A . FA 8 HOH 1 3007 1 HOH HOH B . FA 8 HOH 2 3008 4 HOH HOH B . FA 8 HOH 3 3009 6 HOH HOH B . FA 8 HOH 4 3010 7 HOH HOH B . FA 8 HOH 5 3011 10 HOH HOH B . FA 8 HOH 6 3012 13 HOH HOH B . FA 8 HOH 7 3013 16 HOH HOH B . FA 8 HOH 8 3014 18 HOH HOH B . FA 8 HOH 9 3015 19 HOH HOH B . FA 8 HOH 10 3016 21 HOH HOH B . FA 8 HOH 11 3017 28 HOH HOH B . FA 8 HOH 12 3018 29 HOH HOH B . FA 8 HOH 13 3019 30 HOH HOH B . FA 8 HOH 14 3020 31 HOH HOH B . FA 8 HOH 15 3021 33 HOH HOH B . FA 8 HOH 16 3022 34 HOH HOH B . FA 8 HOH 17 3023 38 HOH HOH B . FA 8 HOH 18 3024 41 HOH HOH B . FA 8 HOH 19 3025 42 HOH HOH B . FA 8 HOH 20 3026 43 HOH HOH B . FA 8 HOH 21 3027 44 HOH HOH B . FA 8 HOH 22 3028 46 HOH HOH B . FA 8 HOH 23 3029 52 HOH HOH B . FA 8 HOH 24 3030 53 HOH HOH B . FA 8 HOH 25 3031 59 HOH HOH B . FA 8 HOH 26 3032 63 HOH HOH B . FA 8 HOH 27 3033 64 HOH HOH B . FA 8 HOH 28 3034 68 HOH HOH B . FA 8 HOH 29 3035 70 HOH HOH B . FA 8 HOH 30 3036 71 HOH HOH B . FA 8 HOH 31 3037 74 HOH HOH B . FA 8 HOH 32 3038 88 HOH HOH B . FA 8 HOH 33 3039 89 HOH HOH B . FA 8 HOH 34 3040 90 HOH HOH B . FA 8 HOH 35 3041 91 HOH HOH B . FA 8 HOH 36 3042 92 HOH HOH B . FA 8 HOH 37 3043 93 HOH HOH B . FA 8 HOH 38 3044 95 HOH HOH B . FA 8 HOH 39 3045 96 HOH HOH B . FA 8 HOH 40 3046 97 HOH HOH B . FA 8 HOH 41 3047 98 HOH HOH B . FA 8 HOH 42 3048 99 HOH HOH B . FA 8 HOH 43 3049 100 HOH HOH B . FA 8 HOH 44 3050 101 HOH HOH B . FA 8 HOH 45 3051 102 HOH HOH B . FA 8 HOH 46 3052 103 HOH HOH B . FA 8 HOH 47 3053 104 HOH HOH B . FA 8 HOH 48 3054 105 HOH HOH B . FA 8 HOH 49 3055 106 HOH HOH B . FA 8 HOH 50 3056 137 HOH HOH B . FA 8 HOH 51 3057 138 HOH HOH B . FA 8 HOH 52 3058 139 HOH HOH B . FA 8 HOH 53 3059 140 HOH HOH B . FA 8 HOH 54 3060 141 HOH HOH B . FA 8 HOH 55 3061 142 HOH HOH B . FA 8 HOH 56 3062 143 HOH HOH B . FA 8 HOH 57 3063 144 HOH HOH B . FA 8 HOH 58 3064 145 HOH HOH B . FA 8 HOH 59 3065 146 HOH HOH B . FA 8 HOH 60 3066 147 HOH HOH B . FA 8 HOH 61 3067 148 HOH HOH B . FA 8 HOH 62 3068 149 HOH HOH B . # loop_ _pdbx_struct_mod_residue.id _pdbx_struct_mod_residue.label_asym_id _pdbx_struct_mod_residue.label_comp_id _pdbx_struct_mod_residue.label_seq_id _pdbx_struct_mod_residue.auth_asym_id _pdbx_struct_mod_residue.auth_comp_id _pdbx_struct_mod_residue.auth_seq_id _pdbx_struct_mod_residue.PDB_ins_code _pdbx_struct_mod_residue.parent_comp_id _pdbx_struct_mod_residue.details 1 A ASN 95 A ASN 95 ? ASN 'GLYCOSYLATION SITE' 2 A ASN 205 A ASN 205 ? ASN 'GLYCOSYLATION SITE' 3 A ASN 241 A ASN 241 ? ASN 'GLYCOSYLATION SITE' 4 A ASN 332 A ASN 332 ? ASN 'GLYCOSYLATION SITE' 5 B ASN 95 B ASN 95 ? ASN 'GLYCOSYLATION SITE' 6 B ASN 205 B ASN 205 ? ASN 'GLYCOSYLATION SITE' 7 B ASN 241 B ASN 241 ? ASN 'GLYCOSYLATION SITE' 8 B ASN 332 B ASN 332 ? ASN 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details dimeric _pdbx_struct_assembly.oligomeric_count 2 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA,EA,FA # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 NE2 ? A HIS 351 ? A HIS 351 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 NA ? M HEM . ? A HEM 605 ? 1_555 87.8 ? 2 NE2 ? A HIS 351 ? A HIS 351 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 NB ? M HEM . ? A HEM 605 ? 1_555 94.3 ? 3 NA ? M HEM . ? A HEM 605 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 NB ? M HEM . ? A HEM 605 ? 1_555 80.9 ? 4 NE2 ? A HIS 351 ? A HIS 351 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 NC ? M HEM . ? A HEM 605 ? 1_555 103.3 ? 5 NA ? M HEM . ? A HEM 605 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 NC ? M HEM . ? A HEM 605 ? 1_555 168.4 ? 6 NB ? M HEM . ? A HEM 605 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 NC ? M HEM . ? A HEM 605 ? 1_555 95.0 ? 7 NE2 ? A HIS 351 ? A HIS 351 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 ND ? M HEM . ? A HEM 605 ? 1_555 95.8 ? 8 NA ? M HEM . ? A HEM 605 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 ND ? M HEM . ? A HEM 605 ? 1_555 99.4 ? 9 NB ? M HEM . ? A HEM 605 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 ND ? M HEM . ? A HEM 605 ? 1_555 169.8 ? 10 NC ? M HEM . ? A HEM 605 ? 1_555 FE ? M HEM . ? A HEM 605 ? 1_555 ND ? M HEM . ? A HEM 605 ? 1_555 82.8 ? 11 NE2 ? B HIS 351 ? B HIS 351 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 NA ? AA HEM . ? B HEM 605 ? 1_555 103.0 ? 12 NE2 ? B HIS 351 ? B HIS 351 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 NB ? AA HEM . ? B HEM 605 ? 1_555 97.7 ? 13 NA ? AA HEM . ? B HEM 605 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 NB ? AA HEM . ? B HEM 605 ? 1_555 81.2 ? 14 NE2 ? B HIS 351 ? B HIS 351 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 NC ? AA HEM . ? B HEM 605 ? 1_555 89.6 ? 15 NA ? AA HEM . ? B HEM 605 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 NC ? AA HEM . ? B HEM 605 ? 1_555 167.3 ? 16 NB ? AA HEM . ? B HEM 605 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 NC ? AA HEM . ? B HEM 605 ? 1_555 97.6 ? 17 NE2 ? B HIS 351 ? B HIS 351 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 ND ? AA HEM . ? B HEM 605 ? 1_555 93.3 ? 18 NA ? AA HEM . ? B HEM 605 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 ND ? AA HEM . ? B HEM 605 ? 1_555 99.3 ? 19 NB ? AA HEM . ? B HEM 605 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 ND ? AA HEM . ? B HEM 605 ? 1_555 168.6 ? 20 NC ? AA HEM . ? B HEM 605 ? 1_555 FE ? AA HEM . ? B HEM 605 ? 1_555 ND ? AA HEM . ? B HEM 605 ? 1_555 79.4 ? 21 O ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OD1 ? A ASP 110 ? A ASP 110 ? 1_555 63.9 ? 22 O ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 O ? A THR 184 ? A THR 184 ? 1_555 73.4 ? 23 OD1 ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 O ? A THR 184 ? A THR 184 ? 1_555 132.3 ? 24 O ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG1 ? A THR 184 ? A THR 184 ? 1_555 130.2 ? 25 OD1 ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG1 ? A THR 184 ? A THR 184 ? 1_555 156.8 ? 26 O ? A THR 184 ? A THR 184 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG1 ? A THR 184 ? A THR 184 ? 1_555 70.1 ? 27 O ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 O ? A PHE 186 ? A PHE 186 ? 1_555 107.3 ? 28 OD1 ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 O ? A PHE 186 ? A PHE 186 ? 1_555 84.0 ? 29 O ? A THR 184 ? A THR 184 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 O ? A PHE 186 ? A PHE 186 ? 1_555 89.4 ? 30 OG1 ? A THR 184 ? A THR 184 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 O ? A PHE 186 ? A PHE 186 ? 1_555 105.0 ? 31 O ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OD1 ? A ASP 188 ? A ASP 188 ? 1_555 151.1 ? 32 OD1 ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OD1 ? A ASP 188 ? A ASP 188 ? 1_555 87.5 ? 33 O ? A THR 184 ? A THR 184 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OD1 ? A ASP 188 ? A ASP 188 ? 1_555 134.6 ? 34 OG1 ? A THR 184 ? A THR 184 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OD1 ? A ASP 188 ? A ASP 188 ? 1_555 75.6 ? 35 O ? A PHE 186 ? A PHE 186 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OD1 ? A ASP 188 ? A ASP 188 ? 1_555 71.5 ? 36 O ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG ? A SER 190 ? A SER 190 ? 1_555 95.9 ? 37 OD1 ? A ASP 110 ? A ASP 110 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG ? A SER 190 ? A SER 190 ? 1_555 88.9 ? 38 O ? A THR 184 ? A THR 184 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG ? A SER 190 ? A SER 190 ? 1_555 116.6 ? 39 OG1 ? A THR 184 ? A THR 184 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG ? A SER 190 ? A SER 190 ? 1_555 72.5 ? 40 O ? A PHE 186 ? A PHE 186 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG ? A SER 190 ? A SER 190 ? 1_555 149.5 ? 41 OD1 ? A ASP 188 ? A ASP 188 ? 1_555 CA ? K CA . ? A CA 1001 ? 1_555 OG ? A SER 190 ? A SER 190 ? 1_555 78.6 ? 42 O ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OD1 ? B ASP 110 ? B ASP 110 ? 1_555 58.5 ? 43 O ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 O ? B THR 184 ? B THR 184 ? 1_555 71.6 ? 44 OD1 ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 O ? B THR 184 ? B THR 184 ? 1_555 110.6 ? 45 O ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG1 ? B THR 184 ? B THR 184 ? 1_555 131.0 ? 46 OD1 ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG1 ? B THR 184 ? B THR 184 ? 1_555 168.1 ? 47 O ? B THR 184 ? B THR 184 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG1 ? B THR 184 ? B THR 184 ? 1_555 70.7 ? 48 O ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 O ? B PHE 186 ? B PHE 186 ? 1_555 111.6 ? 49 OD1 ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 O ? B PHE 186 ? B PHE 186 ? 1_555 66.9 ? 50 O ? B THR 184 ? B THR 184 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 O ? B PHE 186 ? B PHE 186 ? 1_555 94.1 ? 51 OG1 ? B THR 184 ? B THR 184 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 O ? B PHE 186 ? B PHE 186 ? 1_555 101.3 ? 52 O ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OD1 ? B ASP 188 ? B ASP 188 ? 1_555 146.0 ? 53 OD1 ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OD1 ? B ASP 188 ? B ASP 188 ? 1_555 91.5 ? 54 O ? B THR 184 ? B THR 184 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OD1 ? B ASP 188 ? B ASP 188 ? 1_555 139.8 ? 55 OG1 ? B THR 184 ? B THR 184 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OD1 ? B ASP 188 ? B ASP 188 ? 1_555 81.2 ? 56 O ? B PHE 186 ? B PHE 186 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OD1 ? B ASP 188 ? B ASP 188 ? 1_555 63.4 ? 57 O ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG ? B SER 190 ? B SER 190 ? 1_555 84.8 ? 58 OD1 ? B ASP 110 ? B ASP 110 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG ? B SER 190 ? B SER 190 ? 1_555 98.8 ? 59 O ? B THR 184 ? B THR 184 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG ? B SER 190 ? B SER 190 ? 1_555 122.5 ? 60 OG1 ? B THR 184 ? B THR 184 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG ? B SER 190 ? B SER 190 ? 1_555 90.0 ? 61 O ? B PHE 186 ? B PHE 186 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG ? B SER 190 ? B SER 190 ? 1_555 143.3 ? 62 OD1 ? B ASP 188 ? B ASP 188 ? 1_555 CA ? Y CA . ? B CA 1002 ? 1_555 OG ? B SER 190 ? B SER 190 ? 1_555 84.5 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2006-10-17 2 'Structure model' 1 1 2008-05-01 3 'Structure model' 1 2 2011-07-13 4 'Structure model' 1 3 2017-10-18 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' 4 4 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 4 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # _pdbx_audit_revision_item.ordinal 1 _pdbx_audit_revision_item.revision_ordinal 4 _pdbx_audit_revision_item.data_content_type 'Structure model' _pdbx_audit_revision_item.item '_software.name' # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal CNS refinement 0.9 ? 1 MAR345 'data collection' 345DTB ? 2 DENZO 'data reduction' . ? 3 SCALEPACK 'data scaling' . ? 4 AMoRE phasing . ? 5 # _pdbx_validate_close_contact.id 1 _pdbx_validate_close_contact.PDB_model_num 1 _pdbx_validate_close_contact.auth_atom_id_1 C _pdbx_validate_close_contact.auth_asym_id_1 B _pdbx_validate_close_contact.auth_comp_id_1 LYS _pdbx_validate_close_contact.auth_seq_id_1 233 _pdbx_validate_close_contact.PDB_ins_code_1 ? _pdbx_validate_close_contact.label_alt_id_1 ? _pdbx_validate_close_contact.auth_atom_id_2 CD _pdbx_validate_close_contact.auth_asym_id_2 B _pdbx_validate_close_contact.auth_comp_id_2 PRO _pdbx_validate_close_contact.auth_seq_id_2 234 _pdbx_validate_close_contact.PDB_ins_code_2 ? _pdbx_validate_close_contact.label_alt_id_2 ? _pdbx_validate_close_contact.dist 1.76 # loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 N A PRO 9 ? ? CA A PRO 9 ? ? 1.581 1.468 0.113 0.017 N 2 1 N A ILE 24 ? ? CA A ILE 24 ? ? 1.595 1.459 0.136 0.020 N 3 1 N A TYR 172 ? ? CA A TYR 172 ? ? 1.583 1.459 0.124 0.020 N 4 1 N B ARG 67 ? ? CA B ARG 67 ? ? 1.827 1.459 0.368 0.020 N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 N A ILE 24 ? ? CA A ILE 24 ? ? C A ILE 24 ? ? 130.54 111.00 19.54 2.70 N 2 1 CA A PRO 48 ? ? N A PRO 48 ? ? CD A PRO 48 ? ? 103.05 111.70 -8.65 1.40 N 3 1 CB A LEU 86 ? ? CA A LEU 86 ? ? C A LEU 86 ? ? 98.63 110.20 -11.57 1.90 N 4 1 CA A PRO 115 ? ? N A PRO 115 ? ? CD A PRO 115 ? ? 102.71 111.70 -8.99 1.40 N 5 1 C A PRO 115 ? ? N A GLU 116 ? ? CA A GLU 116 ? ? 105.33 121.70 -16.37 2.50 Y 6 1 C A PHE 144 ? ? N A PRO 145 ? ? CD A PRO 145 ? ? 114.89 128.40 -13.51 2.10 Y 7 1 CA A PRO 149 ? ? N A PRO 149 ? ? CD A PRO 149 ? ? 101.79 111.70 -9.91 1.40 N 8 1 N A VAL 166 ? ? CA A VAL 166 ? ? C A VAL 166 ? ? 130.79 111.00 19.79 2.70 N 9 1 C A CYS 167 ? ? N A PRO 168 ? ? CD A PRO 168 ? ? 106.35 128.40 -22.05 2.10 Y 10 1 C A PRO 170 ? ? N A PRO 171 ? ? CD A PRO 171 ? ? 109.51 128.40 -18.89 2.10 Y 11 1 N A PRO 171 ? ? CA A PRO 171 ? ? C A PRO 171 ? ? 137.59 112.10 25.49 2.60 N 12 1 CA A PRO 171 ? ? C A PRO 171 ? ? N A TYR 172 ? ? 141.44 117.20 24.24 2.20 Y 13 1 O A PRO 171 ? ? C A PRO 171 ? ? N A TYR 172 ? ? 110.31 122.70 -12.39 1.60 Y 14 1 CB A TYR 172 ? ? CA A TYR 172 ? ? C A TYR 172 ? ? 93.74 110.40 -16.66 2.00 N 15 1 CA A TYR 172 ? ? CB A TYR 172 ? ? CG A TYR 172 ? ? 133.12 113.40 19.72 1.90 N 16 1 CB A TYR 172 ? ? CG A TYR 172 ? ? CD2 A TYR 172 ? ? 112.20 121.00 -8.80 0.60 N 17 1 CB A TYR 172 ? ? CG A TYR 172 ? ? CD1 A TYR 172 ? ? 129.62 121.00 8.62 0.60 N 18 1 N A GLN 173 ? ? CA A GLN 173 ? ? C A GLN 173 ? ? 131.75 111.00 20.75 2.70 N 19 1 C A SER 208 ? ? N A PRO 209 ? ? CD A PRO 209 ? ? 109.26 128.40 -19.14 2.10 Y 20 1 CA A PRO 209 ? ? N A PRO 209 ? ? CD A PRO 209 ? ? 99.73 111.70 -11.97 1.40 N 21 1 C A LYS 233 ? ? N A PRO 234 ? ? CA A PRO 234 ? ? 137.04 119.30 17.74 1.50 Y 22 1 C A LYS 233 ? ? N A PRO 234 ? ? CD A PRO 234 ? ? 88.09 128.40 -40.31 2.10 Y 23 1 CA A PRO 234 ? ? N A PRO 234 ? ? CD A PRO 234 ? ? 101.92 111.70 -9.78 1.40 N 24 1 N B GLY 7 ? ? CA B GLY 7 ? ? C B GLY 7 ? ? 131.17 113.10 18.07 2.50 N 25 1 C B THR 66 ? ? N B ARG 67 ? ? CA B ARG 67 ? ? 99.01 121.70 -22.69 2.50 Y 26 1 N B ARG 67 ? ? CA B ARG 67 ? ? CB B ARG 67 ? ? 79.85 110.60 -30.75 1.80 N 27 1 N B LEU 119 ? ? CA B LEU 119 ? ? C B LEU 119 ? ? 91.91 111.00 -19.09 2.70 N 28 1 CB B SER 122 ? ? CA B SER 122 ? ? C B SER 122 ? ? 124.40 110.10 14.30 1.90 N 29 1 N B SER 122 ? ? CA B SER 122 ? ? C B SER 122 ? ? 93.35 111.00 -17.65 2.70 N 30 1 CA B HIS 124 ? ? CB B HIS 124 ? ? CG B HIS 124 ? ? 126.27 113.60 12.67 1.70 N 31 1 CB B HIS 124 ? ? CG B HIS 124 ? ? CD2 B HIS 124 ? ? 138.98 131.40 7.58 1.20 N 32 1 C B PRO 171 ? ? N B TYR 172 ? ? CA B TYR 172 ? ? 138.81 121.70 17.11 2.50 Y 33 1 N B SER 174 ? ? CA B SER 174 ? ? C B SER 174 ? ? 130.12 111.00 19.12 2.70 N 34 1 C B LYS 233 ? ? N B PRO 234 ? ? CA B PRO 234 ? ? 165.67 119.30 46.37 1.50 Y 35 1 C B LYS 233 ? ? N B PRO 234 ? ? CD B PRO 234 ? ? 78.12 128.40 -50.28 2.10 Y 36 1 CA B PRO 234 ? ? N B PRO 234 ? ? CD B PRO 234 ? ? 100.00 111.70 -11.70 1.40 N 37 1 CA B PRO 375 ? ? N B PRO 375 ? ? CD B PRO 375 ? ? 102.62 111.70 -9.08 1.40 N 38 1 CB B ASN 571 ? ? CA B ASN 571 ? ? C B ASN 571 ? ? 133.01 110.40 22.61 2.00 N 39 1 CA B PRO 573 ? ? N B PRO 573 ? ? CD B PRO 573 ? ? 92.10 111.70 -19.60 1.40 N 40 1 N B PRO 573 ? ? CA B PRO 573 ? ? C B PRO 573 ? ? 130.41 112.10 18.31 2.60 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 PRO A 9 ? ? -49.79 91.40 2 1 GLU A 17 ? ? 99.46 -6.57 3 1 ASN A 18 ? ? -143.72 23.99 4 1 CYS A 28 ? ? 80.59 -2.91 5 1 ASN A 40 ? ? 74.18 30.17 6 1 LEU A 43 ? ? 21.23 103.97 7 1 ALA A 44 ? ? -29.85 132.17 8 1 LEU A 55 ? ? -141.40 -44.25 9 1 ALA A 56 ? ? -160.06 -12.90 10 1 GLN A 63 ? ? -69.77 26.26 11 1 ARG A 64 ? ? -157.35 -20.50 12 1 ASN A 68 ? ? 48.68 24.30 13 1 THR A 117 ? ? -56.50 -105.90 14 1 LEU A 119 ? ? -112.67 -93.29 15 1 SER A 121 ? ? 82.40 88.21 16 1 SER A 122 ? ? 62.50 85.00 17 1 GLU A 131 ? ? -148.69 -48.90 18 1 ASP A 137 ? ? 43.14 -25.72 19 1 PRO A 145 ? ? -59.85 175.43 20 1 PHE A 160 ? ? -165.06 116.58 21 1 VAL A 166 ? ? -63.13 8.94 22 1 PRO A 168 ? ? -70.63 -140.91 23 1 THR A 169 ? ? -176.96 -69.46 24 1 PRO A 170 ? ? -54.39 -166.33 25 1 PRO A 171 ? ? -64.52 49.27 26 1 TYR A 172 ? ? -139.61 -96.48 27 1 GLN A 173 ? ? -140.26 -136.06 28 1 SER A 174 ? ? 13.32 -53.74 29 1 MET A 232 ? ? -7.48 105.63 30 1 PRO A 234 ? ? 78.31 53.72 31 1 ARG A 245 ? ? 61.47 63.76 32 1 ALA A 256 ? ? -27.46 -32.77 33 1 GLN A 294 ? ? 62.67 -12.99 34 1 ARG A 348 ? ? -66.51 6.33 35 1 GLU A 363 ? ? -49.46 0.79 36 1 ILE A 386 ? ? -99.95 -72.11 37 1 ASP A 389 ? ? -110.71 57.63 38 1 SER A 404 ? ? -76.57 -169.80 39 1 GLN A 409 ? ? -33.08 -13.05 40 1 LYS A 420 ? ? -108.35 40.14 41 1 HIS A 429 ? ? -104.72 44.71 42 1 SER A 459 ? ? -39.70 133.75 43 1 LYS A 474 ? ? -59.57 -70.40 44 1 LYS A 485 ? ? 64.85 -22.12 45 1 ARG A 504 ? ? 39.58 23.69 46 1 HIS A 565 ? ? -110.47 75.05 47 1 ALA A 566 ? ? -52.94 -4.69 48 1 ASP A 583 ? ? -46.07 167.78 49 1 LEU A 585 ? ? 64.02 86.91 50 1 GLU A 594 ? ? 5.68 -93.96 51 1 GLU B 3 ? ? -81.16 39.03 52 1 VAL B 4 ? ? -51.88 79.28 53 1 ALA B 8 ? ? 160.46 141.89 54 1 PRO B 9 ? ? -74.34 -83.19 55 1 VAL B 10 ? ? 64.89 117.37 56 1 PRO B 11 ? ? -53.02 108.32 57 1 CYS B 15 ? ? 68.32 174.87 58 1 ASP B 16 ? ? -102.97 -84.69 59 1 GLU B 17 ? ? 163.00 -75.75 60 1 SER B 19 ? ? -39.03 133.97 61 1 CYS B 28 ? ? 66.08 -3.95 62 1 PRO B 34 ? ? -55.65 -70.72 63 1 ALA B 35 ? ? -56.24 -1.98 64 1 ASN B 40 ? ? 71.58 33.40 65 1 ALA B 56 ? ? -157.16 -9.70 66 1 TRP B 61 ? ? -93.91 -62.44 67 1 GLN B 63 ? ? -8.40 -60.57 68 1 ARG B 64 ? ? -61.61 28.56 69 1 PHE B 113 ? ? -169.67 107.60 70 1 SER B 121 ? ? -154.52 17.13 71 1 SER B 122 ? ? -144.79 -64.47 72 1 GLU B 123 ? ? 6.46 147.12 73 1 ASP B 137 ? ? 59.64 -143.41 74 1 ASN B 147 ? ? 34.91 47.86 75 1 CYS B 167 ? ? 70.57 -147.13 76 1 PRO B 168 ? ? -62.68 -106.64 77 1 THR B 169 ? ? 172.59 -36.22 78 1 PRO B 170 ? ? -63.07 -157.44 79 1 PRO B 171 ? ? -37.87 43.04 80 1 TYR B 172 ? ? -17.30 142.77 81 1 GLN B 173 ? ? -155.67 -133.20 82 1 SER B 174 ? ? 21.78 -85.15 83 1 SER B 185 ? ? -65.89 0.75 84 1 LEU B 187 ? ? -68.75 68.63 85 1 ASN B 205 ? ? -67.18 99.31 86 1 LEU B 210 ? ? -142.60 37.94 87 1 ASN B 231 ? ? -65.71 -90.70 88 1 MET B 232 ? ? -14.04 123.04 89 1 PRO B 234 ? ? 93.70 60.80 90 1 ALA B 256 ? ? -39.34 -30.34 91 1 ILE B 260 ? ? -38.89 -30.14 92 1 ASN B 284 ? ? -118.21 71.77 93 1 VAL B 316 ? ? -108.48 -60.03 94 1 ILE B 325 ? ? -112.99 68.52 95 1 PRO B 326 ? ? -48.22 157.66 96 1 GLN B 329 ? ? -146.30 46.63 97 1 ASN B 333 ? ? -38.97 -26.22 98 1 SER B 334 ? ? -107.31 56.14 99 1 ASP B 336 ? ? -55.82 99.15 100 1 GLU B 363 ? ? -21.61 -28.26 101 1 PRO B 367 ? ? -54.83 106.67 102 1 ILE B 386 ? ? -101.68 -60.79 103 1 LYS B 388 ? ? -99.96 30.29 104 1 ASP B 389 ? ? -161.25 70.15 105 1 LYS B 411 ? ? -174.83 71.30 106 1 ASN B 419 ? ? -145.85 -27.70 107 1 HIS B 429 ? ? -105.26 47.59 108 1 PHE B 455 ? ? -35.99 -27.88 109 1 LYS B 462 ? ? -132.07 -37.09 110 1 ASN B 473 ? ? 174.22 118.66 111 1 LYS B 485 ? ? 77.57 -18.05 112 1 HIS B 565 ? ? -115.87 79.50 113 1 ALA B 566 ? ? -48.48 -16.43 114 1 SER B 580 ? ? -63.89 5.98 115 1 ASP B 583 ? ? -44.73 158.87 116 1 LEU B 585 ? ? 66.85 87.29 117 1 GLU B 594 ? ? -59.25 -85.89 # _pdbx_validate_main_chain_plane.id 1 _pdbx_validate_main_chain_plane.PDB_model_num 1 _pdbx_validate_main_chain_plane.auth_comp_id ASN _pdbx_validate_main_chain_plane.auth_asym_id B _pdbx_validate_main_chain_plane.auth_seq_id 570 _pdbx_validate_main_chain_plane.PDB_ins_code ? _pdbx_validate_main_chain_plane.label_alt_id ? _pdbx_validate_main_chain_plane.improper_torsion_angle 10.86 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 ALPHA-D-MANNOSE MAN 4 'CALCIUM ION' CA 5 'CARBONATE ION' CO3 6 'PROTOPORPHYRIN IX CONTAINING FE' HEM 7 'FORMIC ACID' FMT 8 water HOH #