data_2F7O # _entry.id 2F7O # _audit_conform.dict_name mmcif_pdbx.dic _audit_conform.dict_version 5.286 _audit_conform.dict_location http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic # loop_ _database_2.database_id _database_2.database_code PDB 2F7O RCSB RCSB035553 WWPDB D_1000035553 # loop_ _pdbx_database_related.db_name _pdbx_database_related.db_id _pdbx_database_related.details _pdbx_database_related.content_type PDB 1HTY . unspecified PDB 1HWW . unspecified PDB 1HXK . unspecified PDB 1PS3 . unspecified PDB 1QWN . unspecified PDB 1QWU . unspecified PDB 1QX1 . unspecified PDB 2F7P . unspecified PDB 2F7Q . unspecified PDB 2F7R . unspecified # _pdbx_database_status.entry_id 2F7O _pdbx_database_status.status_code REL _pdbx_database_status.status_code_sf REL _pdbx_database_status.deposit_site RCSB _pdbx_database_status.process_site RCSB _pdbx_database_status.recvd_initial_deposition_date 2005-12-01 _pdbx_database_status.SG_entry N _pdbx_database_status.status_code_mr ? _pdbx_database_status.pdb_format_compatible Y _pdbx_database_status.status_code_cs ? _pdbx_database_status.methods_development_category ? # loop_ _audit_author.name _audit_author.pdbx_ordinal 'Kuntz, D.A.' 1 'Rose, D.R.' 2 # _citation.id primary _citation.title ;Structural Basis of the Inhibition of Golgi alpha-Mannosidase II by Mannostatin A and the Role of the Thiomethyl Moiety in Ligand-Protein Interactions. ; _citation.journal_abbrev J.Am.Chem.Soc. _citation.journal_volume 128 _citation.page_first 8310 _citation.page_last 8319 _citation.year 2006 _citation.journal_id_ASTM JACSAT _citation.country US _citation.journal_id_ISSN 0002-7863 _citation.journal_id_CSD 0004 _citation.book_publisher ? _citation.pdbx_database_id_PubMed 16787095 _citation.pdbx_database_id_DOI 10.1021/ja061216p # loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary 'Kawatkar, S.P.' 1 primary 'Kuntz, D.A.' 2 primary 'Woods, R.J.' 3 primary 'Rose, D.R.' 4 primary 'Boons, G.J.' 5 # _cell.entry_id 2F7O _cell.length_a 69.002 _cell.length_b 109.301 _cell.length_c 138.352 _cell.angle_alpha 90.00 _cell.angle_beta 90.00 _cell.angle_gamma 90.00 _cell.Z_PDB 4 _cell.pdbx_unique_axis ? _cell.length_a_esd ? _cell.length_b_esd ? _cell.length_c_esd ? _cell.angle_alpha_esd ? _cell.angle_beta_esd ? _cell.angle_gamma_esd ? # _symmetry.entry_id 2F7O _symmetry.space_group_name_H-M 'P 21 21 21' _symmetry.pdbx_full_space_group_name_H-M ? _symmetry.cell_setting ? _symmetry.Int_Tables_number 19 _symmetry.space_group_name_Hall ? # loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man 'alpha-mannosidase II' 119701.617 1 3.2.1.114 ? 'CATALYTIC DOMAIN' ? 2 non-polymer man N-ACETYL-D-GLUCOSAMINE 221.208 1 ? ? ? ? 3 non-polymer syn 'ZINC ION' 65.409 1 ? ? ? ? 4 non-polymer syn 'PHOSPHATE ION' 94.971 1 ? ? ? ? 5 non-polymer syn '(1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL' 179.237 1 ? ? ? ? 6 non-polymer syn '(4S)-2-METHYL-2,4-PENTANEDIOL' 118.174 1 ? ? ? ? 7 water nat water 18.015 1048 ? ? ? ? # _entity_name_com.entity_id 1 _entity_name_com.name 'Mannosyl-oligosaccharide 1,3-1,6- alpha-mannosidase; MAN II; Golgi alpha-mannosidase II; AMAN II' # _entity_name_sys.entity_id 1 _entity_name_sys.name E.C.3.2.1.114 # _entity_poly.entity_id 1 _entity_poly.type 'polypeptide(L)' _entity_poly.nstd_linkage no _entity_poly.nstd_monomer no _entity_poly.pdbx_seq_one_letter_code ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_seq_one_letter_code_can ;RSSHHHHHHGEFDDPIRPPLKVARSPRPGQCQDVVQDVPNVDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHK LKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEF VTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQ RQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVD QWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAGQAEFPTL SGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDGMARIEERLEQARRELSLFQHHDGITGTAKT HVVVDYEQRMQEALKACQMVMQQSVYRLLTKPSIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNT LPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSK PEHTSYASNLLLRKNPTSLPLGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSH GDRSGAYLFLPNGPASPVELGQPVVLVTKGKLESSVSVGLPSVVHQTIMRGGAPEIRNLVDIGSLDNTEIVMRLETHIDS GDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQ GVLDNKPVLHIYRLVLEKVNNCVRPSKLHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIGAQGQFGGDHPSAREDLDVS VMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHTQKLDVCHLLPNVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYV SSHSS ; _entity_poly.pdbx_strand_id A _entity_poly.pdbx_target_identifier ? # loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 ARG n 1 2 SER n 1 3 SER n 1 4 HIS n 1 5 HIS n 1 6 HIS n 1 7 HIS n 1 8 HIS n 1 9 HIS n 1 10 GLY n 1 11 GLU n 1 12 PHE n 1 13 ASP n 1 14 ASP n 1 15 PRO n 1 16 ILE n 1 17 ARG n 1 18 PRO n 1 19 PRO n 1 20 LEU n 1 21 LYS n 1 22 VAL n 1 23 ALA n 1 24 ARG n 1 25 SER n 1 26 PRO n 1 27 ARG n 1 28 PRO n 1 29 GLY n 1 30 GLN n 1 31 CYS n 1 32 GLN n 1 33 ASP n 1 34 VAL n 1 35 VAL n 1 36 GLN n 1 37 ASP n 1 38 VAL n 1 39 PRO n 1 40 ASN n 1 41 VAL n 1 42 ASP n 1 43 VAL n 1 44 GLN n 1 45 MET n 1 46 LEU n 1 47 GLU n 1 48 LEU n 1 49 TYR n 1 50 ASP n 1 51 ARG n 1 52 MET n 1 53 SER n 1 54 PHE n 1 55 LYS n 1 56 ASP n 1 57 ILE n 1 58 ASP n 1 59 GLY n 1 60 GLY n 1 61 VAL n 1 62 TRP n 1 63 LYS n 1 64 GLN n 1 65 GLY n 1 66 TRP n 1 67 ASN n 1 68 ILE n 1 69 LYS n 1 70 TYR n 1 71 ASP n 1 72 PRO n 1 73 LEU n 1 74 LYS n 1 75 TYR n 1 76 ASN n 1 77 ALA n 1 78 HIS n 1 79 HIS n 1 80 LYS n 1 81 LEU n 1 82 LYS n 1 83 VAL n 1 84 PHE n 1 85 VAL n 1 86 VAL n 1 87 PRO n 1 88 HIS n 1 89 SER n 1 90 HIS n 1 91 ASN n 1 92 ASP n 1 93 PRO n 1 94 GLY n 1 95 TRP n 1 96 ILE n 1 97 GLN n 1 98 THR n 1 99 PHE n 1 100 GLU n 1 101 GLU n 1 102 TYR n 1 103 TYR n 1 104 GLN n 1 105 HIS n 1 106 ASP n 1 107 THR n 1 108 LYS n 1 109 HIS n 1 110 ILE n 1 111 LEU n 1 112 SER n 1 113 ASN n 1 114 ALA n 1 115 LEU n 1 116 ARG n 1 117 HIS n 1 118 LEU n 1 119 HIS n 1 120 ASP n 1 121 ASN n 1 122 PRO n 1 123 GLU n 1 124 MET n 1 125 LYS n 1 126 PHE n 1 127 ILE n 1 128 TRP n 1 129 ALA n 1 130 GLU n 1 131 ILE n 1 132 SER n 1 133 TYR n 1 134 PHE n 1 135 ALA n 1 136 ARG n 1 137 PHE n 1 138 TYR n 1 139 HIS n 1 140 ASP n 1 141 LEU n 1 142 GLY n 1 143 GLU n 1 144 ASN n 1 145 LYS n 1 146 LYS n 1 147 LEU n 1 148 GLN n 1 149 MET n 1 150 LYS n 1 151 SER n 1 152 ILE n 1 153 VAL n 1 154 LYS n 1 155 ASN n 1 156 GLY n 1 157 GLN n 1 158 LEU n 1 159 GLU n 1 160 PHE n 1 161 VAL n 1 162 THR n 1 163 GLY n 1 164 GLY n 1 165 TRP n 1 166 VAL n 1 167 MET n 1 168 PRO n 1 169 ASP n 1 170 GLU n 1 171 ALA n 1 172 ASN n 1 173 SER n 1 174 HIS n 1 175 TRP n 1 176 ARG n 1 177 ASN n 1 178 VAL n 1 179 LEU n 1 180 LEU n 1 181 GLN n 1 182 LEU n 1 183 THR n 1 184 GLU n 1 185 GLY n 1 186 GLN n 1 187 THR n 1 188 TRP n 1 189 LEU n 1 190 LYS n 1 191 GLN n 1 192 PHE n 1 193 MET n 1 194 ASN n 1 195 VAL n 1 196 THR n 1 197 PRO n 1 198 THR n 1 199 ALA n 1 200 SER n 1 201 TRP n 1 202 ALA n 1 203 ILE n 1 204 ASP n 1 205 PRO n 1 206 PHE n 1 207 GLY n 1 208 HIS n 1 209 SER n 1 210 PRO n 1 211 THR n 1 212 MET n 1 213 PRO n 1 214 TYR n 1 215 ILE n 1 216 LEU n 1 217 GLN n 1 218 LYS n 1 219 SER n 1 220 GLY n 1 221 PHE n 1 222 LYS n 1 223 ASN n 1 224 MET n 1 225 LEU n 1 226 ILE n 1 227 GLN n 1 228 ARG n 1 229 THR n 1 230 HIS n 1 231 TYR n 1 232 SER n 1 233 VAL n 1 234 LYS n 1 235 LYS n 1 236 GLU n 1 237 LEU n 1 238 ALA n 1 239 GLN n 1 240 GLN n 1 241 ARG n 1 242 GLN n 1 243 LEU n 1 244 GLU n 1 245 PHE n 1 246 LEU n 1 247 TRP n 1 248 ARG n 1 249 GLN n 1 250 ILE n 1 251 TRP n 1 252 ASP n 1 253 ASN n 1 254 LYS n 1 255 GLY n 1 256 ASP n 1 257 THR n 1 258 ALA n 1 259 LEU n 1 260 PHE n 1 261 THR n 1 262 HIS n 1 263 MET n 1 264 MET n 1 265 PRO n 1 266 PHE n 1 267 TYR n 1 268 SER n 1 269 TYR n 1 270 ASP n 1 271 ILE n 1 272 PRO n 1 273 HIS n 1 274 THR n 1 275 CYS n 1 276 GLY n 1 277 PRO n 1 278 ASP n 1 279 PRO n 1 280 LYS n 1 281 VAL n 1 282 CYS n 1 283 CYS n 1 284 GLN n 1 285 PHE n 1 286 ASP n 1 287 PHE n 1 288 LYS n 1 289 ARG n 1 290 MET n 1 291 GLY n 1 292 SER n 1 293 PHE n 1 294 GLY n 1 295 LEU n 1 296 SER n 1 297 CYS n 1 298 PRO n 1 299 TRP n 1 300 LYS n 1 301 VAL n 1 302 PRO n 1 303 PRO n 1 304 ARG n 1 305 THR n 1 306 ILE n 1 307 SER n 1 308 ASP n 1 309 GLN n 1 310 ASN n 1 311 VAL n 1 312 ALA n 1 313 ALA n 1 314 ARG n 1 315 SER n 1 316 ASP n 1 317 LEU n 1 318 LEU n 1 319 VAL n 1 320 ASP n 1 321 GLN n 1 322 TRP n 1 323 LYS n 1 324 LYS n 1 325 LYS n 1 326 ALA n 1 327 GLU n 1 328 LEU n 1 329 TYR n 1 330 ARG n 1 331 THR n 1 332 ASN n 1 333 VAL n 1 334 LEU n 1 335 LEU n 1 336 ILE n 1 337 PRO n 1 338 LEU n 1 339 GLY n 1 340 ASP n 1 341 ASP n 1 342 PHE n 1 343 ARG n 1 344 PHE n 1 345 LYS n 1 346 GLN n 1 347 ASN n 1 348 THR n 1 349 GLU n 1 350 TRP n 1 351 ASP n 1 352 VAL n 1 353 GLN n 1 354 ARG n 1 355 VAL n 1 356 ASN n 1 357 TYR n 1 358 GLU n 1 359 ARG n 1 360 LEU n 1 361 PHE n 1 362 GLU n 1 363 HIS n 1 364 ILE n 1 365 ASN n 1 366 SER n 1 367 GLN n 1 368 ALA n 1 369 HIS n 1 370 PHE n 1 371 ASN n 1 372 VAL n 1 373 GLN n 1 374 ALA n 1 375 GLN n 1 376 PHE n 1 377 GLY n 1 378 THR n 1 379 LEU n 1 380 GLN n 1 381 GLU n 1 382 TYR n 1 383 PHE n 1 384 ASP n 1 385 ALA n 1 386 VAL n 1 387 HIS n 1 388 GLN n 1 389 ALA n 1 390 GLU n 1 391 ARG n 1 392 ALA n 1 393 GLY n 1 394 GLN n 1 395 ALA n 1 396 GLU n 1 397 PHE n 1 398 PRO n 1 399 THR n 1 400 LEU n 1 401 SER n 1 402 GLY n 1 403 ASP n 1 404 PHE n 1 405 PHE n 1 406 THR n 1 407 TYR n 1 408 ALA n 1 409 ASP n 1 410 ARG n 1 411 SER n 1 412 ASP n 1 413 ASN n 1 414 TYR n 1 415 TRP n 1 416 SER n 1 417 GLY n 1 418 TYR n 1 419 TYR n 1 420 THR n 1 421 SER n 1 422 ARG n 1 423 PRO n 1 424 TYR n 1 425 HIS n 1 426 LYS n 1 427 ARG n 1 428 MET n 1 429 ASP n 1 430 ARG n 1 431 VAL n 1 432 LEU n 1 433 MET n 1 434 HIS n 1 435 TYR n 1 436 VAL n 1 437 ARG n 1 438 ALA n 1 439 ALA n 1 440 GLU n 1 441 MET n 1 442 LEU n 1 443 SER n 1 444 ALA n 1 445 TRP n 1 446 HIS n 1 447 SER n 1 448 TRP n 1 449 ASP n 1 450 GLY n 1 451 MET n 1 452 ALA n 1 453 ARG n 1 454 ILE n 1 455 GLU n 1 456 GLU n 1 457 ARG n 1 458 LEU n 1 459 GLU n 1 460 GLN n 1 461 ALA n 1 462 ARG n 1 463 ARG n 1 464 GLU n 1 465 LEU n 1 466 SER n 1 467 LEU n 1 468 PHE n 1 469 GLN n 1 470 HIS n 1 471 HIS n 1 472 ASP n 1 473 GLY n 1 474 ILE n 1 475 THR n 1 476 GLY n 1 477 THR n 1 478 ALA n 1 479 LYS n 1 480 THR n 1 481 HIS n 1 482 VAL n 1 483 VAL n 1 484 VAL n 1 485 ASP n 1 486 TYR n 1 487 GLU n 1 488 GLN n 1 489 ARG n 1 490 MET n 1 491 GLN n 1 492 GLU n 1 493 ALA n 1 494 LEU n 1 495 LYS n 1 496 ALA n 1 497 CYS n 1 498 GLN n 1 499 MET n 1 500 VAL n 1 501 MET n 1 502 GLN n 1 503 GLN n 1 504 SER n 1 505 VAL n 1 506 TYR n 1 507 ARG n 1 508 LEU n 1 509 LEU n 1 510 THR n 1 511 LYS n 1 512 PRO n 1 513 SER n 1 514 ILE n 1 515 TYR n 1 516 SER n 1 517 PRO n 1 518 ASP n 1 519 PHE n 1 520 SER n 1 521 PHE n 1 522 SER n 1 523 TYR n 1 524 PHE n 1 525 THR n 1 526 LEU n 1 527 ASP n 1 528 ASP n 1 529 SER n 1 530 ARG n 1 531 TRP n 1 532 PRO n 1 533 GLY n 1 534 SER n 1 535 GLY n 1 536 VAL n 1 537 GLU n 1 538 ASP n 1 539 SER n 1 540 ARG n 1 541 THR n 1 542 THR n 1 543 ILE n 1 544 ILE n 1 545 LEU n 1 546 GLY n 1 547 GLU n 1 548 ASP n 1 549 ILE n 1 550 LEU n 1 551 PRO n 1 552 SER n 1 553 LYS n 1 554 HIS n 1 555 VAL n 1 556 VAL n 1 557 MET n 1 558 HIS n 1 559 ASN n 1 560 THR n 1 561 LEU n 1 562 PRO n 1 563 HIS n 1 564 TRP n 1 565 ARG n 1 566 GLU n 1 567 GLN n 1 568 LEU n 1 569 VAL n 1 570 ASP n 1 571 PHE n 1 572 TYR n 1 573 VAL n 1 574 SER n 1 575 SER n 1 576 PRO n 1 577 PHE n 1 578 VAL n 1 579 SER n 1 580 VAL n 1 581 THR n 1 582 ASP n 1 583 LEU n 1 584 ALA n 1 585 ASN n 1 586 ASN n 1 587 PRO n 1 588 VAL n 1 589 GLU n 1 590 ALA n 1 591 GLN n 1 592 VAL n 1 593 SER n 1 594 PRO n 1 595 VAL n 1 596 TRP n 1 597 SER n 1 598 TRP n 1 599 HIS n 1 600 HIS n 1 601 ASP n 1 602 THR n 1 603 LEU n 1 604 THR n 1 605 LYS n 1 606 THR n 1 607 ILE n 1 608 HIS n 1 609 PRO n 1 610 GLN n 1 611 GLY n 1 612 SER n 1 613 THR n 1 614 THR n 1 615 LYS n 1 616 TYR n 1 617 ARG n 1 618 ILE n 1 619 ILE n 1 620 PHE n 1 621 LYS n 1 622 ALA n 1 623 ARG n 1 624 VAL n 1 625 PRO n 1 626 PRO n 1 627 MET n 1 628 GLY n 1 629 LEU n 1 630 ALA n 1 631 THR n 1 632 TYR n 1 633 VAL n 1 634 LEU n 1 635 THR n 1 636 ILE n 1 637 SER n 1 638 ASP n 1 639 SER n 1 640 LYS n 1 641 PRO n 1 642 GLU n 1 643 HIS n 1 644 THR n 1 645 SER n 1 646 TYR n 1 647 ALA n 1 648 SER n 1 649 ASN n 1 650 LEU n 1 651 LEU n 1 652 LEU n 1 653 ARG n 1 654 LYS n 1 655 ASN n 1 656 PRO n 1 657 THR n 1 658 SER n 1 659 LEU n 1 660 PRO n 1 661 LEU n 1 662 GLY n 1 663 GLN n 1 664 TYR n 1 665 PRO n 1 666 GLU n 1 667 ASP n 1 668 VAL n 1 669 LYS n 1 670 PHE n 1 671 GLY n 1 672 ASP n 1 673 PRO n 1 674 ARG n 1 675 GLU n 1 676 ILE n 1 677 SER n 1 678 LEU n 1 679 ARG n 1 680 VAL n 1 681 GLY n 1 682 ASN n 1 683 GLY n 1 684 PRO n 1 685 THR n 1 686 LEU n 1 687 ALA n 1 688 PHE n 1 689 SER n 1 690 GLU n 1 691 GLN n 1 692 GLY n 1 693 LEU n 1 694 LEU n 1 695 LYS n 1 696 SER n 1 697 ILE n 1 698 GLN n 1 699 LEU n 1 700 THR n 1 701 GLN n 1 702 ASP n 1 703 SER n 1 704 PRO n 1 705 HIS n 1 706 VAL n 1 707 PRO n 1 708 VAL n 1 709 HIS n 1 710 PHE n 1 711 LYS n 1 712 PHE n 1 713 LEU n 1 714 LYS n 1 715 TYR n 1 716 GLY n 1 717 VAL n 1 718 ARG n 1 719 SER n 1 720 HIS n 1 721 GLY n 1 722 ASP n 1 723 ARG n 1 724 SER n 1 725 GLY n 1 726 ALA n 1 727 TYR n 1 728 LEU n 1 729 PHE n 1 730 LEU n 1 731 PRO n 1 732 ASN n 1 733 GLY n 1 734 PRO n 1 735 ALA n 1 736 SER n 1 737 PRO n 1 738 VAL n 1 739 GLU n 1 740 LEU n 1 741 GLY n 1 742 GLN n 1 743 PRO n 1 744 VAL n 1 745 VAL n 1 746 LEU n 1 747 VAL n 1 748 THR n 1 749 LYS n 1 750 GLY n 1 751 LYS n 1 752 LEU n 1 753 GLU n 1 754 SER n 1 755 SER n 1 756 VAL n 1 757 SER n 1 758 VAL n 1 759 GLY n 1 760 LEU n 1 761 PRO n 1 762 SER n 1 763 VAL n 1 764 VAL n 1 765 HIS n 1 766 GLN n 1 767 THR n 1 768 ILE n 1 769 MET n 1 770 ARG n 1 771 GLY n 1 772 GLY n 1 773 ALA n 1 774 PRO n 1 775 GLU n 1 776 ILE n 1 777 ARG n 1 778 ASN n 1 779 LEU n 1 780 VAL n 1 781 ASP n 1 782 ILE n 1 783 GLY n 1 784 SER n 1 785 LEU n 1 786 ASP n 1 787 ASN n 1 788 THR n 1 789 GLU n 1 790 ILE n 1 791 VAL n 1 792 MET n 1 793 ARG n 1 794 LEU n 1 795 GLU n 1 796 THR n 1 797 HIS n 1 798 ILE n 1 799 ASP n 1 800 SER n 1 801 GLY n 1 802 ASP n 1 803 ILE n 1 804 PHE n 1 805 TYR n 1 806 THR n 1 807 ASP n 1 808 LEU n 1 809 ASN n 1 810 GLY n 1 811 LEU n 1 812 GLN n 1 813 PHE n 1 814 ILE n 1 815 LYS n 1 816 ARG n 1 817 ARG n 1 818 ARG n 1 819 LEU n 1 820 ASP n 1 821 LYS n 1 822 LEU n 1 823 PRO n 1 824 LEU n 1 825 GLN n 1 826 ALA n 1 827 ASN n 1 828 TYR n 1 829 TYR n 1 830 PRO n 1 831 ILE n 1 832 PRO n 1 833 SER n 1 834 GLY n 1 835 MET n 1 836 PHE n 1 837 ILE n 1 838 GLU n 1 839 ASP n 1 840 ALA n 1 841 ASN n 1 842 THR n 1 843 ARG n 1 844 LEU n 1 845 THR n 1 846 LEU n 1 847 LEU n 1 848 THR n 1 849 GLY n 1 850 GLN n 1 851 PRO n 1 852 LEU n 1 853 GLY n 1 854 GLY n 1 855 SER n 1 856 SER n 1 857 LEU n 1 858 ALA n 1 859 SER n 1 860 GLY n 1 861 GLU n 1 862 LEU n 1 863 GLU n 1 864 ILE n 1 865 MET n 1 866 GLN n 1 867 ASP n 1 868 ARG n 1 869 ARG n 1 870 LEU n 1 871 ALA n 1 872 SER n 1 873 ASP n 1 874 ASP n 1 875 GLU n 1 876 ARG n 1 877 GLY n 1 878 LEU n 1 879 GLY n 1 880 GLN n 1 881 GLY n 1 882 VAL n 1 883 LEU n 1 884 ASP n 1 885 ASN n 1 886 LYS n 1 887 PRO n 1 888 VAL n 1 889 LEU n 1 890 HIS n 1 891 ILE n 1 892 TYR n 1 893 ARG n 1 894 LEU n 1 895 VAL n 1 896 LEU n 1 897 GLU n 1 898 LYS n 1 899 VAL n 1 900 ASN n 1 901 ASN n 1 902 CYS n 1 903 VAL n 1 904 ARG n 1 905 PRO n 1 906 SER n 1 907 LYS n 1 908 LEU n 1 909 HIS n 1 910 PRO n 1 911 ALA n 1 912 GLY n 1 913 TYR n 1 914 LEU n 1 915 THR n 1 916 SER n 1 917 ALA n 1 918 ALA n 1 919 HIS n 1 920 LYS n 1 921 ALA n 1 922 SER n 1 923 GLN n 1 924 SER n 1 925 LEU n 1 926 LEU n 1 927 ASP n 1 928 PRO n 1 929 LEU n 1 930 ASP n 1 931 LYS n 1 932 PHE n 1 933 ILE n 1 934 PHE n 1 935 ALA n 1 936 GLU n 1 937 ASN n 1 938 GLU n 1 939 TRP n 1 940 ILE n 1 941 GLY n 1 942 ALA n 1 943 GLN n 1 944 GLY n 1 945 GLN n 1 946 PHE n 1 947 GLY n 1 948 GLY n 1 949 ASP n 1 950 HIS n 1 951 PRO n 1 952 SER n 1 953 ALA n 1 954 ARG n 1 955 GLU n 1 956 ASP n 1 957 LEU n 1 958 ASP n 1 959 VAL n 1 960 SER n 1 961 VAL n 1 962 MET n 1 963 ARG n 1 964 ARG n 1 965 LEU n 1 966 THR n 1 967 LYS n 1 968 SER n 1 969 SER n 1 970 ALA n 1 971 LYS n 1 972 THR n 1 973 GLN n 1 974 ARG n 1 975 VAL n 1 976 GLY n 1 977 TYR n 1 978 VAL n 1 979 LEU n 1 980 HIS n 1 981 ARG n 1 982 THR n 1 983 ASN n 1 984 LEU n 1 985 MET n 1 986 GLN n 1 987 CYS n 1 988 GLY n 1 989 THR n 1 990 PRO n 1 991 GLU n 1 992 GLU n 1 993 HIS n 1 994 THR n 1 995 GLN n 1 996 LYS n 1 997 LEU n 1 998 ASP n 1 999 VAL n 1 1000 CYS n 1 1001 HIS n 1 1002 LEU n 1 1003 LEU n 1 1004 PRO n 1 1005 ASN n 1 1006 VAL n 1 1007 ALA n 1 1008 ARG n 1 1009 CYS n 1 1010 GLU n 1 1011 ARG n 1 1012 THR n 1 1013 THR n 1 1014 LEU n 1 1015 THR n 1 1016 PHE n 1 1017 LEU n 1 1018 GLN n 1 1019 ASN n 1 1020 LEU n 1 1021 GLU n 1 1022 HIS n 1 1023 LEU n 1 1024 ASP n 1 1025 GLY n 1 1026 MET n 1 1027 VAL n 1 1028 ALA n 1 1029 PRO n 1 1030 GLU n 1 1031 VAL n 1 1032 CYS n 1 1033 PRO n 1 1034 MET n 1 1035 GLU n 1 1036 THR n 1 1037 ALA n 1 1038 ALA n 1 1039 TYR n 1 1040 VAL n 1 1041 SER n 1 1042 SER n 1 1043 HIS n 1 1044 SER n 1 1045 SER n # _entity_src_gen.entity_id 1 _entity_src_gen.pdbx_src_id 1 _entity_src_gen.pdbx_alt_source_flag sample _entity_src_gen.pdbx_seq_type ? _entity_src_gen.pdbx_beg_seq_num ? _entity_src_gen.pdbx_end_seq_num ? _entity_src_gen.gene_src_common_name 'fruit fly' _entity_src_gen.gene_src_genus Drosophila _entity_src_gen.pdbx_gene_src_gene 'alpha-Man-II, GmII' _entity_src_gen.gene_src_species ? _entity_src_gen.gene_src_strain ? _entity_src_gen.gene_src_tissue ? _entity_src_gen.gene_src_tissue_fraction ? _entity_src_gen.gene_src_details ? _entity_src_gen.pdbx_gene_src_fragment ? _entity_src_gen.pdbx_gene_src_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 7227 _entity_src_gen.pdbx_gene_src_variant ? _entity_src_gen.pdbx_gene_src_cell_line ? _entity_src_gen.pdbx_gene_src_atcc ? _entity_src_gen.pdbx_gene_src_organ ? _entity_src_gen.pdbx_gene_src_organelle ? _entity_src_gen.pdbx_gene_src_cell ? _entity_src_gen.pdbx_gene_src_cellular_location ? _entity_src_gen.host_org_common_name 'fruit fly' _entity_src_gen.pdbx_host_org_scientific_name 'Drosophila melanogaster' _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 7227 _entity_src_gen.host_org_genus Drosophila _entity_src_gen.pdbx_host_org_gene ? _entity_src_gen.pdbx_host_org_organ ? _entity_src_gen.host_org_species ? _entity_src_gen.pdbx_host_org_tissue ? _entity_src_gen.pdbx_host_org_tissue_fraction ? _entity_src_gen.pdbx_host_org_strain 'S2 cells' _entity_src_gen.pdbx_host_org_variant ? _entity_src_gen.pdbx_host_org_cell_line ? _entity_src_gen.pdbx_host_org_atcc ? _entity_src_gen.pdbx_host_org_culture_collection ? _entity_src_gen.pdbx_host_org_cell ? _entity_src_gen.pdbx_host_org_organelle ? _entity_src_gen.pdbx_host_org_cellular_location ? _entity_src_gen.pdbx_host_org_vector_type 'Stable transfection plasmid' _entity_src_gen.pdbx_host_org_vector ? _entity_src_gen.host_org_details ? _entity_src_gen.expression_system_id ? _entity_src_gen.plasmid_name pMTBIP_NHIS _entity_src_gen.plasmid_details ? _entity_src_gen.pdbx_description ? # _struct_ref.id 1 _struct_ref.db_name UNP _struct_ref.db_code MAN2_DROME _struct_ref.pdbx_db_accession Q24451 _struct_ref.entity_id 1 _struct_ref.pdbx_align_begin 76 _struct_ref.pdbx_db_isoform ? _struct_ref.pdbx_seq_one_letter_code ? # _struct_ref_seq.align_id 1 _struct_ref_seq.ref_id 1 _struct_ref_seq.pdbx_PDB_id_code 2F7O _struct_ref_seq.pdbx_strand_id A _struct_ref_seq.seq_align_beg 13 _struct_ref_seq.pdbx_seq_align_beg_ins_code ? _struct_ref_seq.seq_align_end 1045 _struct_ref_seq.pdbx_seq_align_end_ins_code ? _struct_ref_seq.pdbx_db_accession Q24451 _struct_ref_seq.db_align_beg 76 _struct_ref_seq.pdbx_db_align_beg_ins_code ? _struct_ref_seq.db_align_end 1108 _struct_ref_seq.pdbx_db_align_end_ins_code ? _struct_ref_seq.pdbx_auth_seq_align_beg 13 _struct_ref_seq.pdbx_auth_seq_align_end 1045 # loop_ _struct_ref_seq_dif.align_id _struct_ref_seq_dif.pdbx_pdb_id_code _struct_ref_seq_dif.mon_id _struct_ref_seq_dif.pdbx_pdb_strand_id _struct_ref_seq_dif.seq_num _struct_ref_seq_dif.pdbx_pdb_ins_code _struct_ref_seq_dif.pdbx_seq_db_name _struct_ref_seq_dif.pdbx_seq_db_accession_code _struct_ref_seq_dif.db_mon_id _struct_ref_seq_dif.pdbx_seq_db_seq_num _struct_ref_seq_dif.details _struct_ref_seq_dif.pdbx_auth_seq_num _struct_ref_seq_dif.pdbx_ordinal 1 2F7O ARG A 1 ? UNP Q24451 ? ? 'CLONING ATIFACT' 1 1 1 2F7O SER A 2 ? UNP Q24451 ? ? 'CLONING ATIFACT' 2 2 1 2F7O SER A 3 ? UNP Q24451 ? ? 'CLONING ATIFACT' 3 3 1 2F7O HIS A 4 ? UNP Q24451 ? ? 'EXPRESSION TAG' 4 4 1 2F7O HIS A 5 ? UNP Q24451 ? ? 'EXPRESSION TAG' 5 5 1 2F7O HIS A 6 ? UNP Q24451 ? ? 'EXPRESSION TAG' 6 6 1 2F7O HIS A 7 ? UNP Q24451 ? ? 'EXPRESSION TAG' 7 7 1 2F7O HIS A 8 ? UNP Q24451 ? ? 'EXPRESSION TAG' 8 8 1 2F7O HIS A 9 ? UNP Q24451 ? ? 'EXPRESSION TAG' 9 9 1 2F7O GLY A 10 ? UNP Q24451 ? ? 'CLONING ATIFACT' 10 10 1 2F7O GLU A 11 ? UNP Q24451 ? ? 'CLONING ATIFACT' 11 11 1 2F7O PHE A 12 ? UNP Q24451 ? ? 'CLONING ATIFACT' 12 12 # loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA 'L-peptide linking' y ALANINE ? 'C3 H7 N O2' 89.093 ARG 'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1' 175.209 ASN 'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3' 132.118 ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4' 133.103 CYS 'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S' 121.158 GLN 'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3' 146.144 GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4' 147.129 GLY 'peptide linking' y GLYCINE ? 'C2 H5 N O2' 75.067 HIS 'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1' 156.162 HOH non-polymer . WATER ? 'H2 O' 18.015 ILE 'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2' 131.173 LEU 'L-peptide linking' y LEUCINE ? 'C6 H13 N O2' 131.173 LYS 'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1' 147.195 MET 'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S' 149.211 MPD non-polymer . '(4S)-2-METHYL-2,4-PENTANEDIOL' ? 'C6 H14 O2' 118.174 MSN non-polymer . '(1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL' ? 'C6 H13 N O3 S' 179.237 NAG D-saccharide . N-ACETYL-D-GLUCOSAMINE ? 'C8 H15 N O6' 221.208 PHE 'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2' 165.189 PO4 non-polymer . 'PHOSPHATE ION' ? 'O4 P -3' 94.971 PRO 'L-peptide linking' y PROLINE ? 'C5 H9 N O2' 115.130 SER 'L-peptide linking' y SERINE ? 'C3 H7 N O3' 105.093 THR 'L-peptide linking' y THREONINE ? 'C4 H9 N O3' 119.119 TRP 'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2' 204.225 TYR 'L-peptide linking' y TYROSINE ? 'C9 H11 N O3' 181.189 VAL 'L-peptide linking' y VALINE ? 'C5 H11 N O2' 117.146 ZN non-polymer . 'ZINC ION' ? 'Zn 2' 65.409 # _exptl.crystals_number 1 _exptl.method 'X-RAY DIFFRACTION' _exptl.entry_id 2F7O # _exptl_crystal.id 1 _exptl_crystal.density_meas ? _exptl_crystal.density_Matthews 2.18 _exptl_crystal.density_percent_sol 43.53 _exptl_crystal.description ? _exptl_crystal.F_000 ? _exptl_crystal.preparation ? # _exptl_crystal_grow.crystal_id 1 _exptl_crystal_grow.method 'VAPOR DIFFUSION, HANGING DROP' _exptl_crystal_grow.pH 7 _exptl_crystal_grow.temp 298 _exptl_crystal_grow.pdbx_details 'Tris, PEG 6000, MPD, NaCl, pH 7, vapor diffusion, hanging drop, temperature 298K' _exptl_crystal_grow.temp_details ? _exptl_crystal_grow.pdbx_pH_range . # _diffrn.id 1 _diffrn.ambient_temp 100 _diffrn.ambient_temp_details ? _diffrn.crystal_id 1 # _diffrn_detector.diffrn_id 1 _diffrn_detector.detector CCD _diffrn_detector.type 'ADSC QUANTUM 4' _diffrn_detector.pdbx_collection_date 2004-11-11 _diffrn_detector.details ? # _diffrn_radiation.diffrn_id 1 _diffrn_radiation.pdbx_diffrn_protocol 'SINGLE WAVELENGTH' _diffrn_radiation.monochromator ? _diffrn_radiation.wavelength_id 1 _diffrn_radiation.pdbx_monochromatic_or_laue_m_l M _diffrn_radiation.pdbx_scattering_type x-ray # _diffrn_radiation_wavelength.id 1 _diffrn_radiation_wavelength.wavelength 0.91860 _diffrn_radiation_wavelength.wt 1.0 # _diffrn_source.diffrn_id 1 _diffrn_source.source SYNCHROTRON _diffrn_source.type 'CHESS BEAMLINE F1' _diffrn_source.pdbx_wavelength_list 0.91860 _diffrn_source.pdbx_wavelength ? _diffrn_source.pdbx_synchrotron_site CHESS _diffrn_source.pdbx_synchrotron_beamline F1 # _reflns.entry_id 2F7O _reflns.d_resolution_low 30.00 _reflns.d_resolution_high 1.430 _reflns.number_obs 181459 _reflns.percent_possible_obs 97.200 _reflns.pdbx_Rmerge_I_obs 0.101 _reflns.pdbx_chi_squared 1.024 _reflns.pdbx_redundancy 4.1 _reflns.pdbx_scaling_rejects ? _reflns.pdbx_netI_over_sigmaI 12.3 _reflns.pdbx_Rsym_value ? _reflns.observed_criterion_sigma_F 1 _reflns.observed_criterion_sigma_I 1 _reflns.number_all 186718 _reflns.B_iso_Wilson_estimate 14.5 _reflns.R_free_details ? _reflns.limit_h_max ? _reflns.limit_h_min ? _reflns.limit_k_max ? _reflns.limit_k_min ? _reflns.limit_l_max ? _reflns.limit_l_min ? _reflns.observed_criterion_F_max ? _reflns.observed_criterion_F_min ? _reflns.pdbx_ordinal 1 _reflns.pdbx_diffrn_id 1 # _reflns_shell.d_res_low 1.48 _reflns_shell.d_res_high 1.430 _reflns_shell.number_unique_all 11355 _reflns_shell.percent_possible_all 92.300 _reflns_shell.Rmerge_I_obs 0.463 _reflns_shell.pdbx_chi_squared 0.882 _reflns_shell.pdbx_redundancy 3.5 _reflns_shell.number_unique_obs ? _reflns_shell.meanI_over_sigI_obs 2.93 _reflns_shell.pdbx_Rsym_value ? _reflns_shell.percent_possible_obs ? _reflns_shell.number_measured_all ? _reflns_shell.number_measured_obs ? _reflns_shell.pdbx_ordinal 1 _reflns_shell.pdbx_diffrn_id 1 # _refine.ls_d_res_high 1.430 _refine.ls_d_res_low 29.750 _refine.pdbx_ls_sigma_F 2.00 _refine.pdbx_data_cutoff_high_absF 320802.906 _refine.pdbx_data_cutoff_low_absF 0.000 _refine.ls_percent_reflns_obs 95.200 _refine.ls_number_reflns_obs 184146 _refine.pdbx_ls_cross_valid_method THROUGHOUT _refine.pdbx_R_Free_selection_details RANDOM _refine.ls_R_factor_R_work 0.206 _refine.ls_R_factor_R_free 0.235 _refine.ls_percent_reflns_R_free 2.200 _refine.ls_number_reflns_R_free 4103 _refine.ls_R_factor_R_free_error 0.004 _refine.B_iso_mean 17.000 _refine.solvent_model_param_bsol 48.941 _refine.solvent_model_param_ksol 0.358 _refine.pdbx_isotropic_thermal_model RESTRAINED _refine.aniso_B[1][1] -3.310 _refine.aniso_B[2][2] -0.180 _refine.aniso_B[3][3] 3.490 _refine.aniso_B[1][2] 0.000 _refine.aniso_B[1][3] 0.000 _refine.aniso_B[2][3] 0.000 _refine.solvent_model_details 'FLAT MODEL' _refine.entry_id 2F7O _refine.pdbx_ls_sigma_I ? _refine.ls_number_reflns_all 192934 _refine.ls_R_factor_all 0.207 _refine.ls_R_factor_obs 0.2061 _refine.ls_redundancy_reflns_obs ? _refine.ls_number_parameters ? _refine.ls_number_restraints ? _refine.ls_R_factor_R_free_error_details ? _refine.pdbx_method_to_determine_struct 'MOLECULAR REPLACEMENT' _refine.pdbx_starting_model 1HTY _refine.pdbx_stereochem_target_val_spec_case ? _refine.pdbx_stereochemistry_target_values 'Engh & Huber' _refine.occupancy_max ? _refine.occupancy_min ? _refine.details ? _refine.B_iso_min ? _refine.B_iso_max ? _refine.correlation_coeff_Fo_to_Fc ? _refine.correlation_coeff_Fo_to_Fc_free ? _refine.pdbx_solvent_vdw_probe_radii ? _refine.pdbx_solvent_ion_probe_radii ? _refine.pdbx_solvent_shrinkage_radii ? _refine.overall_SU_R_Cruickshank_DPI ? _refine.overall_SU_R_free ? _refine.overall_SU_ML ? _refine.overall_SU_B ? _refine.pdbx_overall_ESU_R_Free ? _refine.pdbx_data_cutoff_high_rms_absF ? _refine.pdbx_overall_ESU_R ? _refine.ls_wR_factor_R_free ? _refine.ls_wR_factor_R_work ? _refine.overall_FOM_free_R_set ? _refine.overall_FOM_work_R_set ? _refine.pdbx_refine_id 'X-RAY DIFFRACTION' _refine.pdbx_diffrn_id 1 _refine.pdbx_TLS_residual_ADP_flag ? _refine.pdbx_overall_phase_error ? _refine.pdbx_overall_SU_R_free_Cruickshank_DPI ? _refine.pdbx_overall_SU_R_Blow_DPI ? _refine.pdbx_overall_SU_R_free_Blow_DPI ? # _refine_analyze.entry_id 2F7O _refine_analyze.Luzzati_coordinate_error_obs 0.18 _refine_analyze.Luzzati_sigma_a_obs 0.18 _refine_analyze.Luzzati_d_res_low_obs 30.00 _refine_analyze.Luzzati_coordinate_error_free 0.21 _refine_analyze.Luzzati_sigma_a_free 0.20 _refine_analyze.Luzzati_d_res_low_free ? _refine_analyze.number_disordered_residues ? _refine_analyze.occupancy_sum_non_hydrogen ? _refine_analyze.occupancy_sum_hydrogen ? _refine_analyze.pdbx_Luzzati_d_res_high_obs ? _refine_analyze.pdbx_refine_id 'X-RAY DIFFRACTION' # _refine_hist.pdbx_refine_id 'X-RAY DIFFRACTION' _refine_hist.cycle_id LAST _refine_hist.pdbx_number_atoms_protein 8181 _refine_hist.pdbx_number_atoms_nucleic_acid 0 _refine_hist.pdbx_number_atoms_ligand 39 _refine_hist.number_atoms_solvent 1048 _refine_hist.number_atoms_total 9268 _refine_hist.d_res_high 1.430 _refine_hist.d_res_low 29.750 # loop_ _refine_ls_restr.type _refine_ls_restr.number _refine_ls_restr.dev_ideal _refine_ls_restr.dev_ideal_target _refine_ls_restr.weight _refine_ls_restr.pdbx_refine_id _refine_ls_restr.pdbx_restraint_function c_bond_d ? 0.023 ? ? 'X-RAY DIFFRACTION' ? c_angle_deg ? 2.000 ? ? 'X-RAY DIFFRACTION' ? c_dihedral_angle_d ? 25.300 ? ? 'X-RAY DIFFRACTION' ? c_improper_angle_d ? 1.420 ? ? 'X-RAY DIFFRACTION' ? c_mcbond_it ? 1.070 ? 1.500 'X-RAY DIFFRACTION' ? c_mcangle_it ? 1.640 ? 2.000 'X-RAY DIFFRACTION' ? c_scbond_it ? 1.730 ? 2.000 'X-RAY DIFFRACTION' ? c_scangle_it ? 2.560 ? 2.500 'X-RAY DIFFRACTION' ? # _refine_ls_shell.d_res_high 1.430 _refine_ls_shell.d_res_low 1.520 _refine_ls_shell.pdbx_total_number_of_bins_used 6 _refine_ls_shell.percent_reflns_obs 90.800 _refine_ls_shell.number_reflns_R_work 28336 _refine_ls_shell.R_factor_all ? _refine_ls_shell.R_factor_R_work 0.297 _refine_ls_shell.R_factor_R_free 0.326 _refine_ls_shell.percent_reflns_R_free 2.000 _refine_ls_shell.number_reflns_R_free 588 _refine_ls_shell.R_factor_R_free_error 0.013 _refine_ls_shell.number_reflns_all ? _refine_ls_shell.number_reflns_obs 28924 _refine_ls_shell.redundancy_reflns_obs ? _refine_ls_shell.pdbx_refine_id 'X-RAY DIFFRACTION' # loop_ _pdbx_xplor_file.serial_no _pdbx_xplor_file.param_file _pdbx_xplor_file.topol_file _pdbx_xplor_file.pdbx_refine_id 1 protein_rep.top protein_rep.param 'X-RAY DIFFRACTION' 2 carbohydrate.top carbohydrate.param 'X-RAY DIFFRACTION' 3 cis_peptide.top cis_peptide.param 'X-RAY DIFFRACTION' 4 water_rep.top water_rep.param 'X-RAY DIFFRACTION' 5 ion.top ion.param 'X-RAY DIFFRACTION' 6 MPD.top MPD.par 'X-RAY DIFFRACTION' 7 PO4.top PO4.par 'X-RAY DIFFRACTION' 8 MSN.top MSN.par 'X-RAY DIFFRACTION' # _struct.entry_id 2F7O _struct.title 'Golgi alpha-mannosidase II complex with mannostatin A' _struct.pdbx_descriptor 'alpha-mannosidase II (E.C.3.2.1.114)' _struct.pdbx_model_details ? _struct.pdbx_CASP_flag ? _struct.pdbx_model_type_details ? # _struct_keywords.entry_id 2F7O _struct_keywords.text 'GLYCOSYL HYDROLASE FAMILY 38, HYDROLASE' _struct_keywords.pdbx_keywords HYDROLASE # loop_ _struct_asym.id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A N N 1 ? B N N 2 ? C N N 3 ? D N N 4 ? E N N 5 ? F N N 6 ? G N N 7 ? # _struct_biol.id 1 # loop_ _struct_conf.conf_type_id _struct_conf.id _struct_conf.pdbx_PDB_helix_id _struct_conf.beg_label_comp_id _struct_conf.beg_label_asym_id _struct_conf.beg_label_seq_id _struct_conf.pdbx_beg_PDB_ins_code _struct_conf.end_label_comp_id _struct_conf.end_label_asym_id _struct_conf.end_label_seq_id _struct_conf.pdbx_end_PDB_ins_code _struct_conf.beg_auth_comp_id _struct_conf.beg_auth_asym_id _struct_conf.beg_auth_seq_id _struct_conf.end_auth_comp_id _struct_conf.end_auth_asym_id _struct_conf.end_auth_seq_id _struct_conf.pdbx_PDB_helix_class _struct_conf.details _struct_conf.pdbx_PDB_helix_length HELX_P HELX_P1 1 MET A 45 ? MET A 52 ? MET A 45 MET A 52 1 ? 8 HELX_P HELX_P2 2 ASP A 71 ? TYR A 75 ? ASP A 71 TYR A 75 5 ? 5 HELX_P HELX_P3 3 THR A 98 ? ASP A 106 ? THR A 98 ASP A 106 1 ? 9 HELX_P HELX_P4 4 ASP A 106 ? ASN A 121 ? ASP A 106 ASN A 121 1 ? 16 HELX_P HELX_P5 5 GLU A 130 ? HIS A 139 ? GLU A 130 HIS A 139 1 ? 10 HELX_P HELX_P6 6 GLY A 142 ? ASN A 155 ? GLY A 142 ASN A 155 1 ? 14 HELX_P HELX_P7 7 HIS A 174 ? ASN A 194 ? HIS A 174 ASN A 194 1 ? 21 HELX_P HELX_P8 8 PRO A 210 ? LYS A 218 ? PRO A 210 LYS A 218 1 ? 9 HELX_P HELX_P9 9 HIS A 230 ? GLN A 240 ? HIS A 230 GLN A 240 1 ? 11 HELX_P HELX_P10 10 ASP A 270 ? THR A 274 ? ASP A 270 THR A 274 5 ? 5 HELX_P HELX_P11 11 ASP A 278 ? CYS A 283 ? ASP A 278 CYS A 283 1 ? 6 HELX_P HELX_P12 12 GLN A 284 ? MET A 290 ? GLN A 284 MET A 290 5 ? 7 HELX_P HELX_P13 13 ASN A 310 ? GLU A 327 ? ASN A 310 GLU A 327 1 ? 18 HELX_P HELX_P14 14 GLN A 346 ? GLN A 367 ? GLN A 346 GLN A 367 1 ? 22 HELX_P HELX_P15 15 ALA A 368 ? PHE A 370 ? ALA A 368 PHE A 370 5 ? 3 HELX_P HELX_P16 16 THR A 378 ? ALA A 392 ? THR A 378 ALA A 392 1 ? 15 HELX_P HELX_P17 17 SER A 416 ? THR A 420 ? SER A 416 THR A 420 5 ? 5 HELX_P HELX_P18 18 ARG A 422 ? TRP A 445 ? ARG A 422 TRP A 445 1 ? 24 HELX_P HELX_P19 19 ASP A 449 ? ALA A 452 ? ASP A 449 ALA A 452 5 ? 4 HELX_P HELX_P20 20 ARG A 453 ? GLN A 469 ? ARG A 453 GLN A 469 1 ? 17 HELX_P HELX_P21 21 LYS A 479 ? LEU A 509 ? LYS A 479 LEU A 509 1 ? 31 HELX_P HELX_P22 22 PRO A 823 ? TYR A 828 ? PRO A 823 TYR A 828 5 ? 6 HELX_P HELX_P23 23 THR A 915 ? ASP A 927 ? THR A 915 ASP A 927 1 ? 13 HELX_P HELX_P24 24 ASP A 998 ? LEU A 1002 ? ASP A 998 LEU A 1002 5 ? 5 HELX_P HELX_P25 25 ASP A 1024 ? VAL A 1027 ? ASP A 1024 VAL A 1027 5 ? 4 # _struct_conf_type.id HELX_P _struct_conf_type.criteria ? _struct_conf_type.reference ? # loop_ _struct_conn.id _struct_conn.conn_type_id _struct_conn.pdbx_leaving_atom_flag _struct_conn.pdbx_PDB_id _struct_conn.ptnr1_label_asym_id _struct_conn.ptnr1_label_comp_id _struct_conn.ptnr1_label_seq_id _struct_conn.ptnr1_label_atom_id _struct_conn.pdbx_ptnr1_label_alt_id _struct_conn.pdbx_ptnr1_PDB_ins_code _struct_conn.pdbx_ptnr1_standard_comp_id _struct_conn.ptnr1_symmetry _struct_conn.ptnr2_label_asym_id _struct_conn.ptnr2_label_comp_id _struct_conn.ptnr2_label_seq_id _struct_conn.ptnr2_label_atom_id _struct_conn.pdbx_ptnr2_label_alt_id _struct_conn.pdbx_ptnr2_PDB_ins_code _struct_conn.ptnr1_auth_asym_id _struct_conn.ptnr1_auth_comp_id _struct_conn.ptnr1_auth_seq_id _struct_conn.ptnr2_auth_asym_id _struct_conn.ptnr2_auth_comp_id _struct_conn.ptnr2_auth_seq_id _struct_conn.ptnr2_symmetry _struct_conn.pdbx_ptnr3_label_atom_id _struct_conn.pdbx_ptnr3_label_seq_id _struct_conn.pdbx_ptnr3_label_comp_id _struct_conn.pdbx_ptnr3_label_asym_id _struct_conn.pdbx_ptnr3_label_alt_id _struct_conn.pdbx_ptnr3_PDB_ins_code _struct_conn.details _struct_conn.pdbx_dist_value _struct_conn.pdbx_value_order disulf1 disulf ? ? A CYS 31 SG ? ? ? 1_555 A CYS 1032 SG ? ? A CYS 31 A CYS 1032 1_555 ? ? ? ? ? ? ? 2.059 ? disulf2 disulf ? ? A CYS 275 SG ? ? ? 1_555 A CYS 282 SG ? ? A CYS 275 A CYS 282 1_555 ? ? ? ? ? ? ? 2.018 ? disulf3 disulf ? ? A CYS 283 SG ? ? ? 1_555 A CYS 297 SG ? ? A CYS 283 A CYS 297 1_555 ? ? ? ? ? ? ? 2.068 ? disulf4 disulf ? ? A CYS 902 SG ? ? ? 1_555 A CYS 987 SG ? ? A CYS 902 A CYS 987 1_555 ? ? ? ? ? ? ? 2.060 ? disulf5 disulf ? ? A CYS 1000 SG ? ? ? 1_555 A CYS 1009 SG ? ? A CYS 1000 A CYS 1009 1_555 ? ? ? ? ? ? ? 2.026 ? covale1 covale ? ? A ASN 194 ND2 ? ? ? 1_555 B NAG . C1 ? ? A ASN 194 A NAG 5004 1_555 ? ? ? ? ? ? ? 1.450 ? metalc1 metalc ? ? C ZN . ZN ? ? ? 1_555 E MSN . O3 ? ? A ZN 5001 A MSN 5002 1_555 ? ? ? ? ? ? ? 2.183 ? metalc2 metalc ? ? C ZN . ZN ? ? ? 1_555 E MSN . O4 ? ? A ZN 5001 A MSN 5002 1_555 ? ? ? ? ? ? ? 2.231 ? metalc3 metalc ? ? C ZN . ZN ? ? ? 1_555 A HIS 471 NE2 ? ? A ZN 5001 A HIS 471 1_555 ? ? ? ? ? ? ? 2.093 ? metalc4 metalc ? ? C ZN . ZN ? ? ? 1_555 A HIS 90 NE2 ? ? A ZN 5001 A HIS 90 1_555 ? ? ? ? ? ? ? 2.131 ? metalc5 metalc ? ? C ZN . ZN ? ? ? 1_555 A ASP 92 OD1 ? ? A ZN 5001 A ASP 92 1_555 ? ? ? ? ? ? ? 2.138 ? metalc6 metalc ? ? C ZN . ZN ? ? ? 1_555 A ASP 204 OD2 ? ? A ZN 5001 A ASP 204 1_555 ? ? ? ? ? ? ? 2.062 ? # loop_ _struct_conn_type.id _struct_conn_type.criteria _struct_conn_type.reference disulf ? ? covale ? ? metalc ? ? # loop_ _struct_mon_prot_cis.pdbx_id _struct_mon_prot_cis.label_comp_id _struct_mon_prot_cis.label_seq_id _struct_mon_prot_cis.label_asym_id _struct_mon_prot_cis.label_alt_id _struct_mon_prot_cis.pdbx_PDB_ins_code _struct_mon_prot_cis.auth_comp_id _struct_mon_prot_cis.auth_seq_id _struct_mon_prot_cis.auth_asym_id _struct_mon_prot_cis.pdbx_label_comp_id_2 _struct_mon_prot_cis.pdbx_label_seq_id_2 _struct_mon_prot_cis.pdbx_label_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_ins_code_2 _struct_mon_prot_cis.pdbx_auth_comp_id_2 _struct_mon_prot_cis.pdbx_auth_seq_id_2 _struct_mon_prot_cis.pdbx_auth_asym_id_2 _struct_mon_prot_cis.pdbx_PDB_model_num _struct_mon_prot_cis.pdbx_omega_angle 1 PHE 405 A . ? PHE 405 A THR 406 A ? THR 406 A 1 0.06 2 TRP 531 A . ? TRP 531 A PRO 532 A ? PRO 532 A 1 -0.96 # loop_ _struct_sheet.id _struct_sheet.type _struct_sheet.number_strands _struct_sheet.details A ? 6 ? B ? 3 ? C ? 2 ? D ? 2 ? E ? 6 ? F ? 5 ? G ? 5 ? H ? 12 ? I ? 5 ? J ? 8 ? K ? 5 ? # loop_ _struct_sheet_order.sheet_id _struct_sheet_order.range_id_1 _struct_sheet_order.range_id_2 _struct_sheet_order.offset _struct_sheet_order.sense A 1 2 ? parallel A 2 3 ? parallel A 3 4 ? anti-parallel A 4 5 ? parallel A 5 6 ? parallel B 1 2 ? parallel B 2 3 ? parallel C 1 2 ? parallel D 1 2 ? anti-parallel E 1 2 ? anti-parallel E 2 3 ? anti-parallel E 3 4 ? anti-parallel E 4 5 ? anti-parallel E 5 6 ? anti-parallel F 1 2 ? anti-parallel F 2 3 ? anti-parallel F 3 4 ? anti-parallel F 4 5 ? anti-parallel G 1 2 ? parallel G 2 3 ? anti-parallel G 3 4 ? anti-parallel G 4 5 ? parallel H 1 2 ? parallel H 2 3 ? anti-parallel H 3 4 ? anti-parallel H 4 5 ? anti-parallel H 5 6 ? anti-parallel H 6 7 ? anti-parallel H 7 8 ? anti-parallel H 8 9 ? anti-parallel H 9 10 ? anti-parallel H 10 11 ? anti-parallel H 11 12 ? anti-parallel I 1 2 ? anti-parallel I 2 3 ? anti-parallel I 3 4 ? anti-parallel I 4 5 ? anti-parallel J 1 2 ? anti-parallel J 2 3 ? anti-parallel J 3 4 ? anti-parallel J 4 5 ? anti-parallel J 5 6 ? anti-parallel J 6 7 ? anti-parallel J 7 8 ? anti-parallel K 1 2 ? anti-parallel K 2 3 ? anti-parallel K 3 4 ? anti-parallel K 4 5 ? anti-parallel # loop_ _struct_sheet_range.sheet_id _struct_sheet_range.id _struct_sheet_range.beg_label_comp_id _struct_sheet_range.beg_label_asym_id _struct_sheet_range.beg_label_seq_id _struct_sheet_range.pdbx_beg_PDB_ins_code _struct_sheet_range.end_label_comp_id _struct_sheet_range.end_label_asym_id _struct_sheet_range.end_label_seq_id _struct_sheet_range.pdbx_end_PDB_ins_code _struct_sheet_range.beg_auth_comp_id _struct_sheet_range.beg_auth_asym_id _struct_sheet_range.beg_auth_seq_id _struct_sheet_range.end_auth_comp_id _struct_sheet_range.end_auth_asym_id _struct_sheet_range.end_auth_seq_id A 1 VAL A 43 ? GLN A 44 ? VAL A 43 GLN A 44 A 2 THR A 399 ? SER A 401 ? THR A 399 SER A 401 A 3 GLU A 244 ? TRP A 247 ? GLU A 244 TRP A 247 A 4 LEU A 259 ? MET A 263 ? LEU A 259 MET A 263 A 5 ASN A 223 ? ILE A 226 ? ASN A 223 ILE A 226 A 6 ALA A 199 ? ALA A 202 ? ALA A 199 ALA A 202 B 1 VAL A 333 ? ASP A 341 ? VAL A 333 ASP A 341 B 2 LEU A 81 ? HIS A 90 ? LEU A 81 HIS A 90 B 3 VAL A 372 ? PHE A 376 ? VAL A 372 PHE A 376 C 1 PHE A 126 ? TRP A 128 ? PHE A 126 TRP A 128 C 2 LEU A 158 ? PHE A 160 ? LEU A 158 PHE A 160 D 1 ALA A 408 ? ARG A 410 ? ALA A 408 ARG A 410 D 2 ASN A 413 ? TYR A 414 ? ASN A 413 TYR A 414 E 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 E 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 E 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 E 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 E 5 VAL A 578 ? ASP A 582 ? VAL A 578 ASP A 582 E 6 PRO A 587 ? VAL A 588 ? PRO A 587 VAL A 588 F 1 PHE A 524 ? ASP A 527 ? PHE A 524 ASP A 527 F 2 ASP A 930 ? PHE A 934 ? ASP A 930 PHE A 934 F 3 SER A 552 ? ASN A 559 ? SER A 552 ASN A 559 F 4 GLY A 628 ? ILE A 636 ? GLY A 628 ILE A 636 F 5 GLN A 945 ? PHE A 946 ? GLN A 945 PHE A 946 G 1 THR A 542 ? ILE A 543 ? THR A 542 ILE A 543 G 2 ARG A 565 ? VAL A 573 ? ARG A 565 VAL A 573 G 3 THR A 606 ? VAL A 624 ? THR A 606 VAL A 624 G 4 ALA A 590 ? ASP A 601 ? ALA A 590 ASP A 601 G 5 THR A 644 ? TYR A 646 ? THR A 644 TYR A 646 H 1 LYS A 669 ? GLY A 671 ? LYS A 669 GLY A 671 H 2 SER A 648 ? LEU A 652 ? SER A 648 LEU A 652 H 3 VAL A 745 ? LYS A 749 ? VAL A 745 LYS A 749 H 4 SER A 754 ? LEU A 760 ? SER A 754 LEU A 760 H 5 VAL A 763 ? MET A 769 ? VAL A 763 MET A 769 H 6 GLU A 775 ? VAL A 780 ? GLU A 775 VAL A 780 H 7 VAL A 888 ? LYS A 898 ? VAL A 888 LYS A 898 H 8 THR A 842 ? THR A 848 ? THR A 842 THR A 848 H 9 GLY A 834 ? GLU A 838 ? GLY A 834 GLU A 838 H 10 ILE A 803 ? LEU A 808 ? ILE A 803 LEU A 808 H 11 GLN A 812 ? ARG A 817 ? GLN A 812 ARG A 817 H 12 ALA A 911 ? GLY A 912 ? ALA A 911 GLY A 912 I 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 I 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 I 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 I 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 I 5 SER A 736 ? PRO A 737 ? SER A 736 PRO A 737 J 1 ILE A 676 ? ARG A 679 ? ILE A 676 ARG A 679 J 2 THR A 685 ? PHE A 688 ? THR A 685 PHE A 688 J 3 LEU A 694 ? GLN A 698 ? LEU A 694 GLN A 698 J 4 VAL A 706 ? TYR A 715 ? VAL A 706 TYR A 715 J 5 THR A 788 ? THR A 796 ? THR A 788 THR A 796 J 6 GLU A 861 ? ARG A 869 ? GLU A 861 ARG A 869 J 7 LEU A 852 ? SER A 855 ? LEU A 852 SER A 855 J 8 TYR A 829 ? ILE A 831 ? TYR A 829 ILE A 831 K 1 LEU A 957 ? ARG A 964 ? LEU A 957 ARG A 964 K 2 GLN A 973 ? ARG A 981 ? GLN A 973 ARG A 981 K 3 THR A 1036 ? HIS A 1043 ? THR A 1036 HIS A 1043 K 4 VAL A 1006 ? THR A 1012 ? VAL A 1006 THR A 1012 K 5 ASN A 1019 ? HIS A 1022 ? ASN A 1019 HIS A 1022 # loop_ _pdbx_struct_sheet_hbond.sheet_id _pdbx_struct_sheet_hbond.range_id_1 _pdbx_struct_sheet_hbond.range_id_2 _pdbx_struct_sheet_hbond.range_1_label_atom_id _pdbx_struct_sheet_hbond.range_1_label_comp_id _pdbx_struct_sheet_hbond.range_1_label_asym_id _pdbx_struct_sheet_hbond.range_1_label_seq_id _pdbx_struct_sheet_hbond.range_1_PDB_ins_code _pdbx_struct_sheet_hbond.range_1_auth_atom_id _pdbx_struct_sheet_hbond.range_1_auth_comp_id _pdbx_struct_sheet_hbond.range_1_auth_asym_id _pdbx_struct_sheet_hbond.range_1_auth_seq_id _pdbx_struct_sheet_hbond.range_2_label_atom_id _pdbx_struct_sheet_hbond.range_2_label_comp_id _pdbx_struct_sheet_hbond.range_2_label_asym_id _pdbx_struct_sheet_hbond.range_2_label_seq_id _pdbx_struct_sheet_hbond.range_2_PDB_ins_code _pdbx_struct_sheet_hbond.range_2_auth_atom_id _pdbx_struct_sheet_hbond.range_2_auth_comp_id _pdbx_struct_sheet_hbond.range_2_auth_asym_id _pdbx_struct_sheet_hbond.range_2_auth_seq_id A 1 2 N VAL A 43 ? N VAL A 43 O SER A 401 ? O SER A 401 A 2 3 O LEU A 400 ? O LEU A 400 N LEU A 246 ? N LEU A 246 A 3 4 N PHE A 245 ? N PHE A 245 O THR A 261 ? O THR A 261 A 4 5 O HIS A 262 ? O HIS A 262 N MET A 224 ? N MET A 224 A 5 6 O LEU A 225 ? O LEU A 225 N ALA A 202 ? N ALA A 202 B 1 2 O ILE A 336 ? O ILE A 336 N PHE A 84 ? N PHE A 84 B 2 3 N VAL A 83 ? N VAL A 83 O GLN A 373 ? O GLN A 373 C 1 2 N PHE A 126 ? N PHE A 126 O GLU A 159 ? O GLU A 159 D 1 2 N ARG A 410 ? N ARG A 410 O ASN A 413 ? O ASN A 413 E 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 E 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 E 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 E 4 5 O VAL A 633 ? O VAL A 633 N THR A 581 ? N THR A 581 E 5 6 N VAL A 580 ? N VAL A 580 O VAL A 588 ? O VAL A 588 F 1 2 N THR A 525 ? N THR A 525 O ILE A 933 ? O ILE A 933 F 2 3 O PHE A 932 ? O PHE A 932 N VAL A 556 ? N VAL A 556 F 3 4 N VAL A 555 ? N VAL A 555 O TYR A 632 ? O TYR A 632 F 4 5 N LEU A 629 ? N LEU A 629 O PHE A 946 ? O PHE A 946 G 1 2 N ILE A 543 ? N ILE A 543 O TYR A 572 ? O TYR A 572 G 2 3 N VAL A 573 ? N VAL A 573 O TYR A 616 ? O TYR A 616 G 3 4 O GLN A 610 ? O GLN A 610 N SER A 597 ? N SER A 597 G 4 5 N VAL A 592 ? N VAL A 592 O SER A 645 ? O SER A 645 H 1 2 O LYS A 669 ? O LYS A 669 N LEU A 651 ? N LEU A 651 H 2 3 N LEU A 652 ? N LEU A 652 O VAL A 745 ? O VAL A 745 H 3 4 N LEU A 746 ? N LEU A 746 O SER A 757 ? O SER A 757 H 4 5 N SER A 754 ? N SER A 754 O MET A 769 ? O MET A 769 H 5 6 N ILE A 768 ? N ILE A 768 O GLU A 775 ? O GLU A 775 H 6 7 N VAL A 780 ? N VAL A 780 O VAL A 888 ? O VAL A 888 H 7 8 O VAL A 895 ? O VAL A 895 N THR A 845 ? N THR A 845 H 8 9 O LEU A 846 ? O LEU A 846 N MET A 835 ? N MET A 835 H 9 10 O PHE A 836 ? O PHE A 836 N TYR A 805 ? N TYR A 805 H 10 11 N PHE A 804 ? N PHE A 804 O ARG A 816 ? O ARG A 816 H 11 12 N PHE A 813 ? N PHE A 813 O GLY A 912 ? O GLY A 912 I 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 I 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 I 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 I 4 5 N LYS A 714 ? N LYS A 714 O SER A 736 ? O SER A 736 J 1 2 N ILE A 676 ? N ILE A 676 O PHE A 688 ? O PHE A 688 J 2 3 N ALA A 687 ? N ALA A 687 O LYS A 695 ? O LYS A 695 J 3 4 N ILE A 697 ? N ILE A 697 O VAL A 706 ? O VAL A 706 J 4 5 N LYS A 711 ? N LYS A 711 O ARG A 793 ? O ARG A 793 J 5 6 N LEU A 794 ? N LEU A 794 O LEU A 862 ? O LEU A 862 J 6 7 O MET A 865 ? O MET A 865 N GLY A 853 ? N GLY A 853 J 7 8 O GLY A 854 ? O GLY A 854 N TYR A 829 ? N TYR A 829 K 1 2 N ARG A 963 ? N ARG A 963 O GLY A 976 ? O GLY A 976 K 2 3 N LEU A 979 ? N LEU A 979 O ALA A 1037 ? O ALA A 1037 K 3 4 O SER A 1042 ? O SER A 1042 N ALA A 1007 ? N ALA A 1007 K 4 5 N ARG A 1011 ? N ARG A 1011 O LEU A 1020 ? O LEU A 1020 # loop_ _struct_site.id _struct_site.pdbx_evidence_code _struct_site.pdbx_auth_asym_id _struct_site.pdbx_auth_comp_id _struct_site.pdbx_auth_seq_id _struct_site.pdbx_auth_ins_code _struct_site.pdbx_num_residues _struct_site.details AC1 Software ? ? ? ? 1 'BINDING SITE FOR RESIDUE NAG A 5004' AC2 Software ? ? ? ? 5 'BINDING SITE FOR RESIDUE ZN A 5001' AC3 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE PO4 A 5005' AC4 Software ? ? ? ? 17 'BINDING SITE FOR RESIDUE MSN A 5002' AC5 Software ? ? ? ? 8 'BINDING SITE FOR RESIDUE MPD A 5003' # loop_ _struct_site_gen.id _struct_site_gen.site_id _struct_site_gen.pdbx_num_res _struct_site_gen.label_comp_id _struct_site_gen.label_asym_id _struct_site_gen.label_seq_id _struct_site_gen.pdbx_auth_ins_code _struct_site_gen.auth_comp_id _struct_site_gen.auth_asym_id _struct_site_gen.auth_seq_id _struct_site_gen.label_atom_id _struct_site_gen.label_alt_id _struct_site_gen.symmetry _struct_site_gen.details 1 AC1 1 ASN A 194 ? ASN A 194 . ? 1_555 ? 2 AC2 5 HIS A 90 ? HIS A 90 . ? 1_555 ? 3 AC2 5 ASP A 92 ? ASP A 92 . ? 1_555 ? 4 AC2 5 ASP A 204 ? ASP A 204 . ? 1_555 ? 5 AC2 5 HIS A 471 ? HIS A 471 . ? 1_555 ? 6 AC2 5 MSN E . ? MSN A 5002 . ? 1_555 ? 7 AC3 9 GLN A 567 ? GLN A 567 . ? 1_555 ? 8 AC3 9 ARG A 770 ? ARG A 770 . ? 1_555 ? 9 AC3 9 ARG A 893 ? ARG A 893 . ? 1_555 ? 10 AC3 9 SER A 924 ? SER A 924 . ? 1_555 ? 11 AC3 9 HOH G . ? HOH A 5380 . ? 1_555 ? 12 AC3 9 HOH G . ? HOH A 5387 . ? 1_555 ? 13 AC3 9 HOH G . ? HOH A 5388 . ? 1_555 ? 14 AC3 9 HOH G . ? HOH A 5458 . ? 1_555 ? 15 AC3 9 HOH G . ? HOH A 5460 . ? 1_555 ? 16 AC4 17 HIS A 90 ? HIS A 90 . ? 1_555 ? 17 AC4 17 ASP A 92 ? ASP A 92 . ? 1_555 ? 18 AC4 17 TRP A 95 ? TRP A 95 . ? 1_555 ? 19 AC4 17 ASP A 204 ? ASP A 204 . ? 1_555 ? 20 AC4 17 PHE A 206 ? PHE A 206 . ? 1_555 ? 21 AC4 17 ARG A 228 ? ARG A 228 . ? 1_555 ? 22 AC4 17 TYR A 269 ? TYR A 269 . ? 1_555 ? 23 AC4 17 ASP A 341 ? ASP A 341 . ? 1_555 ? 24 AC4 17 TRP A 415 ? TRP A 415 . ? 1_555 ? 25 AC4 17 HIS A 471 ? HIS A 471 . ? 1_555 ? 26 AC4 17 ASP A 472 ? ASP A 472 . ? 1_555 ? 27 AC4 17 TYR A 727 ? TYR A 727 . ? 1_555 ? 28 AC4 17 ARG A 876 ? ARG A 876 . ? 1_555 ? 29 AC4 17 ZN C . ? ZN A 5001 . ? 1_555 ? 30 AC4 17 HOH G . ? HOH A 5084 . ? 1_555 ? 31 AC4 17 HOH G . ? HOH A 5085 . ? 1_555 ? 32 AC4 17 HOH G . ? HOH A 5164 . ? 1_555 ? 33 AC5 8 LYS A 63 ? LYS A 63 . ? 1_555 ? 34 AC5 8 GLN A 64 ? GLN A 64 . ? 1_555 ? 35 AC5 8 TYR A 267 ? TYR A 267 . ? 1_555 ? 36 AC5 8 HIS A 273 ? HIS A 273 . ? 1_555 ? 37 AC5 8 HOH G . ? HOH A 5289 . ? 1_555 ? 38 AC5 8 HOH G . ? HOH A 5299 . ? 1_555 ? 39 AC5 8 HOH G . ? HOH A 5301 . ? 1_555 ? 40 AC5 8 HOH G . ? HOH A 5302 . ? 1_555 ? # _atom_sites.entry_id 2F7O _atom_sites.fract_transf_matrix[1][1] 0.014492 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 0.009149 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 0.007228 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 # loop_ _atom_type.symbol C N O P S ZN # loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_PDB_model_num ATOM 1 N N . CYS A 1 31 ? 44.371 36.138 -19.080 1.00 24.01 ? 31 CYS A N 1 ATOM 2 C CA . CYS A 1 31 ? 43.594 37.350 -18.651 1.00 21.19 ? 31 CYS A CA 1 ATOM 3 C C . CYS A 1 31 ? 42.113 37.132 -18.757 1.00 21.19 ? 31 CYS A C 1 ATOM 4 O O . CYS A 1 31 ? 41.615 36.579 -19.747 1.00 20.97 ? 31 CYS A O 1 ATOM 5 C CB . CYS A 1 31 ? 43.899 38.567 -19.529 1.00 21.78 ? 31 CYS A CB 1 ATOM 6 S SG . CYS A 1 31 ? 45.613 39.176 -19.510 1.00 22.59 ? 31 CYS A SG 1 ATOM 7 N N . GLN A 1 32 ? 41.403 37.610 -17.753 1.00 19.28 ? 32 GLN A N 1 ATOM 8 C CA . GLN A 1 32 ? 39.947 37.536 -17.705 1.00 20.63 ? 32 GLN A CA 1 ATOM 9 C C . GLN A 1 32 ? 39.383 38.501 -18.792 1.00 19.33 ? 32 GLN A C 1 ATOM 10 O O . GLN A 1 32 ? 39.949 39.596 -19.038 1.00 18.68 ? 32 GLN A O 1 ATOM 11 C CB . GLN A 1 32 ? 39.481 37.982 -16.305 1.00 23.47 ? 32 GLN A CB 1 ATOM 12 C CG . GLN A 1 32 ? 38.148 37.499 -15.942 1.00 28.24 ? 32 GLN A CG 1 ATOM 13 C CD . GLN A 1 32 ? 37.808 37.663 -14.446 1.00 29.86 ? 32 GLN A CD 1 ATOM 14 O OE1 . GLN A 1 32 ? 36.738 37.247 -14.014 1.00 33.60 ? 32 GLN A OE1 1 ATOM 15 N NE2 . GLN A 1 32 ? 38.708 38.272 -13.662 1.00 31.47 ? 32 GLN A NE2 1 ATOM 16 N N . ASP A 1 33 ? 38.312 38.094 -19.480 1.00 18.38 ? 33 ASP A N 1 ATOM 17 C CA . ASP A 1 33 ? 37.653 38.928 -20.483 1.00 17.92 ? 33 ASP A CA 1 ATOM 18 C C . ASP A 1 33 ? 36.706 39.885 -19.719 1.00 17.67 ? 33 ASP A C 1 ATOM 19 O O . ASP A 1 33 ? 35.732 39.458 -19.078 1.00 17.55 ? 33 ASP A O 1 ATOM 20 C CB . ASP A 1 33 ? 36.874 38.001 -21.450 1.00 19.26 ? 33 ASP A CB 1 ATOM 21 C CG . ASP A 1 33 ? 36.199 38.753 -22.581 1.00 21.09 ? 33 ASP A CG 1 ATOM 22 O OD1 . ASP A 1 33 ? 35.747 39.898 -22.363 1.00 19.84 ? 33 ASP A OD1 1 ATOM 23 O OD2 . ASP A 1 33 ? 36.091 38.172 -23.710 1.00 22.43 ? 33 ASP A OD2 1 ATOM 24 N N . VAL A 1 34 ? 36.975 41.176 -19.795 1.00 13.69 ? 34 VAL A N 1 ATOM 25 C CA . VAL A 1 34 ? 36.174 42.139 -19.024 1.00 12.84 ? 34 VAL A CA 1 ATOM 26 C C . VAL A 1 34 ? 34.985 42.746 -19.766 1.00 12.78 ? 34 VAL A C 1 ATOM 27 O O . VAL A 1 34 ? 34.247 43.625 -19.256 1.00 12.56 ? 34 VAL A O 1 ATOM 28 C CB . VAL A 1 34 ? 37.078 43.260 -18.492 1.00 12.74 ? 34 VAL A CB 1 ATOM 29 C CG1 . VAL A 1 34 ? 38.347 42.677 -17.841 1.00 12.65 ? 34 VAL A CG1 1 ATOM 30 C CG2 . VAL A 1 34 ? 37.513 44.180 -19.649 1.00 10.59 ? 34 VAL A CG2 1 ATOM 31 N N . VAL A 1 35 ? 34.717 42.197 -20.957 1.00 10.20 ? 35 VAL A N 1 ATOM 32 C CA . VAL A 1 35 ? 33.632 42.708 -21.760 1.00 12.49 ? 35 VAL A CA 1 ATOM 33 C C . VAL A 1 35 ? 32.482 41.757 -21.997 1.00 11.30 ? 35 VAL A C 1 ATOM 34 O O . VAL A 1 35 ? 31.335 42.157 -21.923 1.00 12.41 ? 35 VAL A O 1 ATOM 35 C CB . VAL A 1 35 ? 34.179 43.080 -23.148 1.00 14.24 ? 35 VAL A CB 1 ATOM 36 C CG1 . VAL A 1 35 ? 33.021 43.478 -24.095 1.00 14.41 ? 35 VAL A CG1 1 ATOM 37 C CG2 . VAL A 1 35 ? 35.283 44.129 -23.062 1.00 13.84 ? 35 VAL A CG2 1 ATOM 38 N N . GLN A 1 36 ? 32.823 40.497 -22.271 1.00 13.59 ? 36 GLN A N 1 ATOM 39 C CA . GLN A 1 36 ? 31.845 39.479 -22.696 1.00 17.48 ? 36 GLN A CA 1 ATOM 40 C C . GLN A 1 36 ? 31.197 38.559 -21.720 1.00 19.39 ? 36 GLN A C 1 ATOM 41 O O . GLN A 1 36 ? 30.233 37.862 -22.065 1.00 20.73 ? 36 GLN A O 1 ATOM 42 C CB . GLN A 1 36 ? 32.503 38.633 -23.788 1.00 16.08 ? 36 GLN A CB 1 ATOM 43 C CG . GLN A 1 36 ? 32.900 39.495 -24.959 1.00 16.50 ? 36 GLN A CG 1 ATOM 44 C CD . GLN A 1 36 ? 33.477 38.736 -26.153 1.00 18.13 ? 36 GLN A CD 1 ATOM 45 O OE1 . GLN A 1 36 ? 32.846 38.651 -27.238 1.00 19.34 ? 36 GLN A OE1 1 ATOM 46 N NE2 . GLN A 1 36 ? 34.668 38.212 -25.981 1.00 16.99 ? 36 GLN A NE2 1 ATOM 47 N N . ASP A 1 37 ? 31.734 38.511 -20.516 1.00 19.96 ? 37 ASP A N 1 ATOM 48 C CA . ASP A 1 37 ? 31.211 37.665 -19.464 1.00 21.05 ? 37 ASP A CA 1 ATOM 49 C C . ASP A 1 37 ? 30.562 38.495 -18.327 1.00 19.87 ? 37 ASP A C 1 ATOM 50 O O . ASP A 1 37 ? 31.273 39.148 -17.540 1.00 21.03 ? 37 ASP A O 1 ATOM 51 C CB . ASP A 1 37 ? 32.367 36.817 -18.890 1.00 23.11 ? 37 ASP A CB 1 ATOM 52 C CG . ASP A 1 37 ? 33.000 35.922 -19.938 1.00 24.97 ? 37 ASP A CG 1 ATOM 53 O OD1 . ASP A 1 37 ? 32.231 35.386 -20.762 1.00 25.98 ? 37 ASP A OD1 1 ATOM 54 O OD2 . ASP A 1 37 ? 34.240 35.754 -19.942 1.00 23.77 ? 37 ASP A OD2 1 ATOM 55 N N . VAL A 1 38 ? 29.240 38.460 -18.250 1.00 18.34 ? 38 VAL A N 1 ATOM 56 C CA . VAL A 1 38 ? 28.544 39.194 -17.194 1.00 17.95 ? 38 VAL A CA 1 ATOM 57 C C . VAL A 1 38 ? 28.709 38.463 -15.844 1.00 17.31 ? 38 VAL A C 1 ATOM 58 O O . VAL A 1 38 ? 28.283 37.308 -15.699 1.00 18.63 ? 38 VAL A O 1 ATOM 59 C CB . VAL A 1 38 ? 27.066 39.324 -17.513 1.00 16.84 ? 38 VAL A CB 1 ATOM 60 C CG1 . VAL A 1 38 ? 26.337 40.116 -16.413 1.00 19.34 ? 38 VAL A CG1 1 ATOM 61 C CG2 . VAL A 1 38 ? 26.915 39.996 -18.946 1.00 15.93 ? 38 VAL A CG2 1 ATOM 62 N N . PRO A 1 39 ? 29.322 39.116 -14.842 1.00 15.13 ? 39 PRO A N 1 ATOM 63 C CA . PRO A 1 39 ? 29.482 38.432 -13.547 1.00 14.92 ? 39 PRO A CA 1 ATOM 64 C C . PRO A 1 39 ? 28.144 38.069 -12.934 1.00 15.24 ? 39 PRO A C 1 ATOM 65 O O . PRO A 1 39 ? 27.148 38.807 -13.034 1.00 14.71 ? 39 PRO A O 1 ATOM 66 C CB . PRO A 1 39 ? 30.231 39.453 -12.661 1.00 13.26 ? 39 PRO A CB 1 ATOM 67 C CG . PRO A 1 39 ? 31.034 40.298 -13.699 1.00 10.43 ? 39 PRO A CG 1 ATOM 68 C CD . PRO A 1 39 ? 30.058 40.397 -14.897 1.00 13.82 ? 39 PRO A CD 1 ATOM 69 N N . ASN A 1 40 ? 28.144 36.923 -12.241 1.00 15.97 ? 40 ASN A N 1 ATOM 70 C CA . ASN A 1 40 ? 26.974 36.469 -11.521 1.00 17.01 ? 40 ASN A CA 1 ATOM 71 C C . ASN A 1 40 ? 27.236 36.820 -10.036 1.00 15.99 ? 40 ASN A C 1 ATOM 72 O O . ASN A 1 40 ? 28.122 36.253 -9.408 1.00 17.28 ? 40 ASN A O 1 ATOM 73 C CB . ASN A 1 40 ? 26.830 34.971 -11.732 1.00 21.22 ? 40 ASN A CB 1 ATOM 74 C CG . ASN A 1 40 ? 25.637 34.410 -11.013 1.00 26.75 ? 40 ASN A CG 1 ATOM 75 O OD1 . ASN A 1 40 ? 24.509 34.911 -11.166 1.00 31.75 ? 40 ASN A OD1 1 ATOM 76 N ND2 . ASN A 1 40 ? 25.864 33.372 -10.204 1.00 30.02 ? 40 ASN A ND2 1 ATOM 77 N N . VAL A 1 41 ? 26.500 37.803 -9.519 1.00 14.45 ? 41 VAL A N 1 ATOM 78 C CA . VAL A 1 41 ? 26.681 38.241 -8.135 1.00 13.18 ? 41 VAL A CA 1 ATOM 79 C C . VAL A 1 41 ? 25.320 38.251 -7.473 1.00 13.29 ? 41 VAL A C 1 ATOM 80 O O . VAL A 1 41 ? 24.292 38.320 -8.164 1.00 13.32 ? 41 VAL A O 1 ATOM 81 C CB . VAL A 1 41 ? 27.327 39.648 -8.072 1.00 12.12 ? 41 VAL A CB 1 ATOM 82 C CG1 . VAL A 1 41 ? 28.739 39.598 -8.634 1.00 13.95 ? 41 VAL A CG1 1 ATOM 83 C CG2 . VAL A 1 41 ? 26.480 40.695 -8.869 1.00 11.82 ? 41 VAL A CG2 1 ATOM 84 N N . ASP A 1 42 ? 25.283 38.136 -6.151 1.00 13.70 ? 42 ASP A N 1 ATOM 85 C CA . ASP A 1 42 ? 24.027 38.131 -5.428 1.00 12.90 ? 42 ASP A CA 1 ATOM 86 C C . ASP A 1 42 ? 23.348 39.498 -5.430 1.00 12.53 ? 42 ASP A C 1 ATOM 87 O O . ASP A 1 42 ? 22.135 39.577 -5.394 1.00 14.17 ? 42 ASP A O 1 ATOM 88 C CB . ASP A 1 42 ? 24.233 37.637 -3.962 1.00 13.55 ? 42 ASP A CB 1 ATOM 89 C CG . ASP A 1 42 ? 24.785 36.254 -3.903 1.00 15.54 ? 42 ASP A CG 1 ATOM 90 O OD1 . ASP A 1 42 ? 24.157 35.384 -4.546 1.00 18.26 ? 42 ASP A OD1 1 ATOM 91 O OD2 . ASP A 1 42 ? 25.822 35.977 -3.241 1.00 13.77 ? 42 ASP A OD2 1 ATOM 92 N N . VAL A 1 43 ? 24.127 40.571 -5.444 1.00 11.87 ? 43 VAL A N 1 ATOM 93 C CA . VAL A 1 43 ? 23.584 41.911 -5.423 1.00 12.25 ? 43 VAL A CA 1 ATOM 94 C C . VAL A 1 43 ? 24.368 42.708 -6.460 1.00 9.30 ? 43 VAL A C 1 ATOM 95 O O . VAL A 1 43 ? 25.608 42.796 -6.381 1.00 10.89 ? 43 VAL A O 1 ATOM 96 C CB . VAL A 1 43 ? 23.812 42.609 -4.049 1.00 11.34 ? 43 VAL A CB 1 ATOM 97 C CG1 . VAL A 1 43 ? 23.306 44.056 -4.070 1.00 12.56 ? 43 VAL A CG1 1 ATOM 98 C CG2 . VAL A 1 43 ? 23.067 41.763 -2.897 1.00 11.37 ? 43 VAL A CG2 1 ATOM 99 N N . GLN A 1 44 ? 23.682 43.210 -7.453 1.00 10.82 ? 44 GLN A N 1 ATOM 100 C CA . GLN A 1 44 ? 24.318 44.045 -8.478 1.00 9.88 ? 44 GLN A CA 1 ATOM 101 C C . GLN A 1 44 ? 23.587 45.357 -8.291 1.00 9.86 ? 44 GLN A C 1 ATOM 102 O O . GLN A 1 44 ? 22.357 45.431 -8.480 1.00 8.01 ? 44 GLN A O 1 ATOM 103 C CB . GLN A 1 44 ? 24.130 43.395 -9.878 1.00 10.28 ? 44 GLN A CB 1 ATOM 104 C CG . GLN A 1 44 ? 25.239 43.835 -10.857 1.00 11.05 ? 44 GLN A CG 1 ATOM 105 C CD . GLN A 1 44 ? 25.269 45.387 -10.956 1.00 9.89 ? 44 GLN A CD 1 ATOM 106 O OE1 . GLN A 1 44 ? 24.251 46.020 -11.237 1.00 11.23 ? 44 GLN A OE1 1 ATOM 107 N NE2 . GLN A 1 44 ? 26.433 45.972 -10.719 1.00 7.82 ? 44 GLN A NE2 1 ATOM 108 N N . MET A 1 45 ? 24.299 46.454 -7.920 1.00 7.62 ? 45 MET A N 1 ATOM 109 C CA . MET A 1 45 ? 23.593 47.669 -7.555 1.00 8.52 ? 45 MET A CA 1 ATOM 110 C C . MET A 1 45 ? 22.718 48.333 -8.618 1.00 7.96 ? 45 MET A C 1 ATOM 111 O O . MET A 1 45 ? 21.715 48.935 -8.224 1.00 9.72 ? 45 MET A O 1 ATOM 112 C CB . MET A 1 45 ? 24.561 48.677 -6.893 1.00 10.01 ? 45 MET A CB 1 ATOM 113 C CG . MET A 1 45 ? 25.201 48.153 -5.603 1.00 9.75 ? 45 MET A CG 1 ATOM 114 S SD . MET A 1 45 ? 23.992 47.893 -4.286 1.00 11.26 ? 45 MET A SD 1 ATOM 115 C CE . MET A 1 45 ? 23.270 49.643 -4.158 1.00 13.61 ? 45 MET A CE 1 ATOM 116 N N . LEU A 1 46 ? 23.081 48.275 -9.905 1.00 8.95 ? 46 LEU A N 1 ATOM 117 C CA . LEU A 1 46 ? 22.193 48.840 -10.949 1.00 9.89 ? 46 LEU A CA 1 ATOM 118 C C . LEU A 1 46 ? 20.870 48.020 -10.996 1.00 9.81 ? 46 LEU A C 1 ATOM 119 O O . LEU A 1 46 ? 19.770 48.599 -11.102 1.00 11.74 ? 46 LEU A O 1 ATOM 120 C CB . LEU A 1 46 ? 22.855 48.812 -12.332 1.00 11.70 ? 46 LEU A CB 1 ATOM 121 C CG . LEU A 1 46 ? 22.098 49.593 -13.422 1.00 11.30 ? 46 LEU A CG 1 ATOM 122 C CD1 . LEU A 1 46 ? 22.131 51.142 -13.214 1.00 11.76 ? 46 LEU A CD1 1 ATOM 123 C CD2 . LEU A 1 46 ? 22.683 49.178 -14.779 1.00 11.52 ? 46 LEU A CD2 1 ATOM 124 N N . GLU A 1 47 ? 20.976 46.688 -10.837 1.00 10.00 ? 47 GLU A N 1 ATOM 125 C CA . GLU A 1 47 ? 19.761 45.873 -10.888 1.00 11.68 ? 47 GLU A CA 1 ATOM 126 C C . GLU A 1 47 ? 18.937 46.139 -9.641 1.00 11.81 ? 47 GLU A C 1 ATOM 127 O O . GLU A 1 47 ? 17.715 46.273 -9.707 1.00 12.42 ? 47 GLU A O 1 ATOM 128 C CB . GLU A 1 47 ? 20.108 44.388 -11.028 1.00 13.76 ? 47 GLU A CB 1 ATOM 129 C CG . GLU A 1 47 ? 18.882 43.465 -11.223 1.00 19.88 ? 47 GLU A CG 1 ATOM 130 C CD . GLU A 1 47 ? 18.210 43.059 -9.931 1.00 25.46 ? 47 GLU A CD 1 ATOM 131 O OE1 . GLU A 1 47 ? 18.791 43.247 -8.834 1.00 23.39 ? 47 GLU A OE1 1 ATOM 132 O OE2 . GLU A 1 47 ? 17.072 42.533 -10.006 1.00 29.68 ? 47 GLU A OE2 1 ATOM 133 N N . LEU A 1 48 ? 19.596 46.297 -8.501 1.00 9.57 ? 48 LEU A N 1 ATOM 134 C CA . LEU A 1 48 ? 18.895 46.577 -7.254 1.00 10.15 ? 48 LEU A CA 1 ATOM 135 C C . LEU A 1 48 ? 18.147 47.874 -7.348 1.00 10.58 ? 48 LEU A C 1 ATOM 136 O O . LEU A 1 48 ? 16.976 47.981 -6.915 1.00 13.68 ? 48 LEU A O 1 ATOM 137 C CB . LEU A 1 48 ? 19.876 46.630 -6.050 1.00 9.63 ? 48 LEU A CB 1 ATOM 138 C CG . LEU A 1 48 ? 19.116 46.849 -4.731 1.00 13.04 ? 48 LEU A CG 1 ATOM 139 C CD1 . LEU A 1 48 ? 17.996 45.758 -4.638 1.00 16.23 ? 48 LEU A CD1 1 ATOM 140 C CD2 . LEU A 1 48 ? 20.086 46.821 -3.546 1.00 13.57 ? 48 LEU A CD2 1 ATOM 141 N N . TYR A 1 49 ? 18.816 48.897 -7.879 1.00 10.77 ? 49 TYR A N 1 ATOM 142 C CA . TYR A 1 49 ? 18.169 50.227 -8.053 1.00 11.73 ? 49 TYR A CA 1 ATOM 143 C C . TYR A 1 49 ? 16.910 50.130 -8.930 1.00 10.96 ? 49 TYR A C 1 ATOM 144 O O . TYR A 1 49 ? 15.896 50.755 -8.619 1.00 10.12 ? 49 TYR A O 1 ATOM 145 C CB . TYR A 1 49 ? 19.206 51.167 -8.684 1.00 10.97 ? 49 TYR A CB 1 ATOM 146 C CG . TYR A 1 49 ? 19.763 52.120 -7.666 1.00 10.72 ? 49 TYR A CG 1 ATOM 147 C CD1 . TYR A 1 49 ? 20.222 51.631 -6.422 1.00 10.67 ? 49 TYR A CD1 1 ATOM 148 C CD2 . TYR A 1 49 ? 19.768 53.511 -7.879 1.00 10.80 ? 49 TYR A CD2 1 ATOM 149 C CE1 . TYR A 1 49 ? 20.650 52.453 -5.458 1.00 11.00 ? 49 TYR A CE1 1 ATOM 150 C CE2 . TYR A 1 49 ? 20.172 54.390 -6.882 1.00 11.18 ? 49 TYR A CE2 1 ATOM 151 C CZ . TYR A 1 49 ? 20.622 53.864 -5.651 1.00 10.44 ? 49 TYR A CZ 1 ATOM 152 O OH . TYR A 1 49 ? 20.949 54.645 -4.573 1.00 10.20 ? 49 TYR A OH 1 ATOM 153 N N . ASP A 1 50 ? 16.995 49.296 -9.962 1.00 13.60 ? 50 ASP A N 1 ATOM 154 C CA . ASP A 1 50 ? 15.866 49.153 -10.908 1.00 14.84 ? 50 ASP A CA 1 ATOM 155 C C . ASP A 1 50 ? 14.643 48.616 -10.160 1.00 17.17 ? 50 ASP A C 1 ATOM 156 O O . ASP A 1 50 ? 13.519 49.102 -10.361 1.00 16.85 ? 50 ASP A O 1 ATOM 157 C CB . ASP A 1 50 ? 16.294 48.226 -12.039 1.00 17.54 ? 50 ASP A CB 1 ATOM 158 C CG . ASP A 1 50 ? 15.516 48.438 -13.303 1.00 22.53 ? 50 ASP A CG 1 ATOM 159 O OD1 . ASP A 1 50 ? 14.863 49.488 -13.474 1.00 24.03 ? 50 ASP A OD1 1 ATOM 160 O OD2 . ASP A 1 50 ? 15.601 47.527 -14.157 1.00 27.04 ? 50 ASP A OD2 1 ATOM 161 N N . ARG A 1 51 ? 14.863 47.622 -9.305 1.00 16.88 ? 51 ARG A N 1 ATOM 162 C CA . ARG A 1 51 ? 13.753 47.009 -8.514 1.00 17.45 ? 51 ARG A CA 1 ATOM 163 C C . ARG A 1 51 ? 13.246 47.732 -7.273 1.00 17.13 ? 51 ARG A C 1 ATOM 164 O O . ARG A 1 51 ? 12.086 47.568 -6.925 1.00 17.93 ? 51 ARG A O 1 ATOM 165 C CB . ARG A 1 51 ? 14.120 45.624 -7.978 1.00 19.72 ? 51 ARG A CB 1 ATOM 166 C CG . ARG A 1 51 ? 14.682 44.666 -8.901 1.00 23.90 ? 51 ARG A CG 1 ATOM 167 C CD . ARG A 1 51 ? 14.721 43.322 -8.223 1.00 27.06 ? 51 ARG A CD 1 ATOM 168 N NE . ARG A 1 51 ? 16.057 43.037 -7.740 1.00 29.58 ? 51 ARG A NE 1 ATOM 169 C CZ . ARG A 1 51 ? 16.442 43.007 -6.474 1.00 31.37 ? 51 ARG A CZ 1 ATOM 170 N NH1 . ARG A 1 51 ? 15.579 43.255 -5.479 1.00 33.15 ? 51 ARG A NH1 1 ATOM 171 N NH2 . ARG A 1 51 ? 17.712 42.699 -6.213 1.00 31.61 ? 51 ARG A NH2 1 ATOM 172 N N . MET A 1 52 ? 14.115 48.419 -6.538 1.00 15.69 ? 52 MET A N 1 ATOM 173 C CA . MET A 1 52 ? 13.747 49.112 -5.283 1.00 18.55 ? 52 MET A CA 1 ATOM 174 C C . MET A 1 52 ? 12.735 50.212 -5.419 1.00 17.51 ? 52 MET A C 1 ATOM 175 O O . MET A 1 52 ? 12.755 50.917 -6.422 1.00 18.24 ? 52 MET A O 1 ATOM 176 C CB . MET A 1 52 ? 14.978 49.800 -4.685 1.00 18.63 ? 52 MET A CB 1 ATOM 177 C CG . MET A 1 52 ? 15.891 48.893 -3.990 1.00 19.15 ? 52 MET A CG 1 ATOM 178 S SD . MET A 1 52 ? 17.447 49.808 -3.633 1.00 20.22 ? 52 MET A SD 1 ATOM 179 C CE . MET A 1 52 ? 16.770 51.005 -2.434 1.00 16.78 ? 52 MET A CE 1 ATOM 180 N N . SER A 1 53 ? 11.883 50.420 -4.413 1.00 18.65 ? 53 SER A N 1 ATOM 181 C CA . SER A 1 53 ? 10.901 51.508 -4.501 1.00 19.05 ? 53 SER A CA 1 ATOM 182 C C . SER A 1 53 ? 11.361 52.883 -3.991 1.00 18.39 ? 53 SER A C 1 ATOM 183 O O A SER A 1 53 ? 10.857 53.936 -4.441 0.50 19.81 ? 53 SER A O 1 ATOM 184 O O B SER A 1 53 ? 10.566 53.867 -4.116 0.50 18.98 ? 53 SER A O 1 ATOM 185 C CB . SER A 1 53 ? 9.610 51.109 -3.773 1.00 19.56 ? 53 SER A CB 1 ATOM 186 O OG A SER A 1 53 ? 8.936 50.113 -4.531 0.50 19.21 ? 53 SER A OG 1 ATOM 187 O OG B SER A 1 53 ? 9.476 51.611 -2.451 0.50 15.57 ? 53 SER A OG 1 ATOM 188 N N . PHE A 1 54 ? 12.287 52.876 -3.041 1.00 17.16 ? 54 PHE A N 1 ATOM 189 C CA . PHE A 1 54 ? 12.783 54.132 -2.461 1.00 16.53 ? 54 PHE A CA 1 ATOM 190 C C . PHE A 1 54 ? 11.753 54.943 -1.647 1.00 16.75 ? 54 PHE A C 1 ATOM 191 O O . PHE A 1 54 ? 11.925 56.141 -1.429 1.00 16.88 ? 54 PHE A O 1 ATOM 192 C CB . PHE A 1 54 ? 13.350 55.040 -3.575 1.00 14.83 ? 54 PHE A CB 1 ATOM 193 C CG . PHE A 1 54 ? 14.628 54.538 -4.165 1.00 13.46 ? 54 PHE A CG 1 ATOM 194 C CD1 . PHE A 1 54 ? 15.862 54.775 -3.549 1.00 12.34 ? 54 PHE A CD1 1 ATOM 195 C CD2 . PHE A 1 54 ? 14.604 53.795 -5.334 1.00 13.07 ? 54 PHE A CD2 1 ATOM 196 C CE1 . PHE A 1 54 ? 17.063 54.267 -4.108 1.00 12.27 ? 54 PHE A CE1 1 ATOM 197 C CE2 . PHE A 1 54 ? 15.815 53.268 -5.906 1.00 12.82 ? 54 PHE A CE2 1 ATOM 198 C CZ . PHE A 1 54 ? 17.042 53.509 -5.286 1.00 11.42 ? 54 PHE A CZ 1 ATOM 199 N N . LYS A 1 55 ? 10.654 54.318 -1.234 1.00 17.31 ? 55 LYS A N 1 ATOM 200 C CA . LYS A 1 55 ? 9.672 55.051 -0.395 1.00 18.22 ? 55 LYS A CA 1 ATOM 201 C C . LYS A 1 55 ? 10.285 55.431 0.920 1.00 17.75 ? 55 LYS A C 1 ATOM 202 O O . LYS A 1 55 ? 10.991 54.648 1.528 1.00 19.33 ? 55 LYS A O 1 ATOM 203 C CB . LYS A 1 55 ? 8.439 54.184 -0.038 1.00 20.27 ? 55 LYS A CB 1 ATOM 204 C CG . LYS A 1 55 ? 7.667 53.693 -1.217 1.00 23.53 ? 55 LYS A CG 1 ATOM 205 C CD . LYS A 1 55 ? 7.525 54.788 -2.253 1.00 23.30 ? 55 LYS A CD 1 ATOM 206 C CE . LYS A 1 55 ? 6.682 54.331 -3.416 1.00 26.38 ? 55 LYS A CE 1 ATOM 207 N NZ . LYS A 1 55 ? 6.380 55.516 -4.272 1.00 25.04 ? 55 LYS A NZ 1 ATOM 208 N N . ASP A 1 56 ? 9.977 56.622 1.394 1.00 17.29 ? 56 ASP A N 1 ATOM 209 C CA . ASP A 1 56 ? 10.536 57.127 2.629 1.00 16.30 ? 56 ASP A CA 1 ATOM 210 C C . ASP A 1 56 ? 9.502 57.097 3.778 1.00 17.87 ? 56 ASP A C 1 ATOM 211 O O . ASP A 1 56 ? 8.967 58.118 4.207 1.00 17.99 ? 56 ASP A O 1 ATOM 212 C CB . ASP A 1 56 ? 11.039 58.546 2.356 1.00 14.92 ? 56 ASP A CB 1 ATOM 213 C CG . ASP A 1 56 ? 11.693 59.191 3.571 1.00 12.60 ? 56 ASP A CG 1 ATOM 214 O OD1 . ASP A 1 56 ? 12.186 58.509 4.508 1.00 14.08 ? 56 ASP A OD1 1 ATOM 215 O OD2 . ASP A 1 56 ? 11.742 60.446 3.560 1.00 14.68 ? 56 ASP A OD2 1 ATOM 216 N N . ILE A 1 57 ? 9.238 55.910 4.294 1.00 18.91 ? 57 ILE A N 1 ATOM 217 C CA A ILE A 1 57 ? 8.262 55.817 5.353 0.50 20.48 ? 57 ILE A CA 1 ATOM 218 C CA B ILE A 1 57 ? 8.341 55.624 5.352 0.50 20.45 ? 57 ILE A CA 1 ATOM 219 C C . ILE A 1 57 ? 8.860 55.825 6.733 1.00 20.56 ? 57 ILE A C 1 ATOM 220 O O . ILE A 1 57 ? 10.016 55.462 6.946 1.00 20.69 ? 57 ILE A O 1 ATOM 221 C CB A ILE A 1 57 ? 7.393 54.583 5.205 0.50 21.62 ? 57 ILE A CB 1 ATOM 222 C CB B ILE A 1 57 ? 7.772 54.211 5.131 0.50 22.03 ? 57 ILE A CB 1 ATOM 223 C CG1 A ILE A 1 57 ? 8.285 53.359 4.963 0.50 21.89 ? 57 ILE A CG1 1 ATOM 224 C CG1 B ILE A 1 57 ? 6.991 54.209 3.809 0.50 21.43 ? 57 ILE A CG1 1 ATOM 225 C CG2 A ILE A 1 57 ? 6.366 54.820 4.107 0.50 20.38 ? 57 ILE A CG2 1 ATOM 226 C CG2 B ILE A 1 57 ? 6.957 53.753 6.354 0.50 20.25 ? 57 ILE A CG2 1 ATOM 227 C CD1 A ILE A 1 57 ? 7.536 52.043 4.999 0.50 22.38 ? 57 ILE A CD1 1 ATOM 228 C CD1 B ILE A 1 57 ? 6.695 52.830 3.227 0.50 23.57 ? 57 ILE A CD1 1 ATOM 229 N N . ASP A 1 58 ? 8.033 56.239 7.679 1.00 20.47 ? 58 ASP A N 1 ATOM 230 C CA . ASP A 1 58 ? 8.433 56.345 9.044 1.00 20.15 ? 58 ASP A CA 1 ATOM 231 C C . ASP A 1 58 ? 8.491 54.918 9.566 1.00 19.82 ? 58 ASP A C 1 ATOM 232 O O . ASP A 1 58 ? 7.488 54.231 9.614 1.00 19.30 ? 58 ASP A O 1 ATOM 233 C CB . ASP A 1 58 ? 7.415 57.178 9.846 1.00 21.84 ? 58 ASP A CB 1 ATOM 234 C CG . ASP A 1 58 ? 7.890 57.466 11.268 1.00 24.67 ? 58 ASP A CG 1 ATOM 235 O OD1 . ASP A 1 58 ? 8.841 56.815 11.748 1.00 23.68 ? 58 ASP A OD1 1 ATOM 236 O OD2 . ASP A 1 58 ? 7.321 58.360 11.940 1.00 27.26 ? 58 ASP A OD2 1 ATOM 237 N N . GLY A 1 59 ? 9.677 54.454 9.940 1.00 17.96 ? 59 GLY A N 1 ATOM 238 C CA . GLY A 1 59 ? 9.776 53.107 10.417 1.00 16.90 ? 59 GLY A CA 1 ATOM 239 C C . GLY A 1 59 ? 9.723 52.968 11.932 1.00 13.75 ? 59 GLY A C 1 ATOM 240 O O . GLY A 1 59 ? 9.946 51.858 12.439 1.00 15.53 ? 59 GLY A O 1 ATOM 241 N N . GLY A 1 60 ? 9.409 54.050 12.657 1.00 14.67 ? 60 GLY A N 1 ATOM 242 C CA . GLY A 1 60 ? 9.341 54.016 14.111 1.00 15.79 ? 60 GLY A CA 1 ATOM 243 C C . GLY A 1 60 ? 10.622 54.592 14.693 1.00 15.35 ? 60 GLY A C 1 ATOM 244 O O . GLY A 1 60 ? 11.188 55.516 14.090 1.00 15.44 ? 60 GLY A O 1 ATOM 245 N N . VAL A 1 61 ? 11.112 54.058 15.810 1.00 15.46 ? 61 VAL A N 1 ATOM 246 C CA . VAL A 1 61 ? 12.315 54.624 16.417 1.00 14.28 ? 61 VAL A CA 1 ATOM 247 C C . VAL A 1 61 ? 13.507 54.499 15.425 1.00 13.63 ? 61 VAL A C 1 ATOM 248 O O . VAL A 1 61 ? 14.357 55.392 15.388 1.00 12.61 ? 61 VAL A O 1 ATOM 249 C CB . VAL A 1 61 ? 12.612 54.011 17.747 1.00 14.35 ? 61 VAL A CB 1 ATOM 250 C CG1 . VAL A 1 61 ? 11.404 54.254 18.701 1.00 14.25 ? 61 VAL A CG1 1 ATOM 251 C CG2 . VAL A 1 61 ? 12.856 52.542 17.583 1.00 15.83 ? 61 VAL A CG2 1 ATOM 252 N N . TRP A 1 62 ? 13.564 53.431 14.631 1.00 12.57 ? 62 TRP A N 1 ATOM 253 C CA . TRP A 1 62 ? 14.602 53.341 13.574 1.00 12.20 ? 62 TRP A CA 1 ATOM 254 C C . TRP A 1 62 ? 13.839 54.042 12.432 1.00 13.08 ? 62 TRP A C 1 ATOM 255 O O . TRP A 1 62 ? 13.045 53.428 11.691 1.00 12.59 ? 62 TRP A O 1 ATOM 256 C CB . TRP A 1 62 ? 14.946 51.889 13.215 1.00 11.64 ? 62 TRP A CB 1 ATOM 257 C CG . TRP A 1 62 ? 15.986 51.801 12.110 1.00 10.13 ? 62 TRP A CG 1 ATOM 258 C CD1 . TRP A 1 62 ? 16.673 52.862 11.531 1.00 8.50 ? 62 TRP A CD1 1 ATOM 259 C CD2 . TRP A 1 62 ? 16.350 50.636 11.352 1.00 10.01 ? 62 TRP A CD2 1 ATOM 260 N NE1 . TRP A 1 62 ? 17.405 52.415 10.461 1.00 9.85 ? 62 TRP A NE1 1 ATOM 261 C CE2 . TRP A 1 62 ? 17.235 51.057 10.332 1.00 11.34 ? 62 TRP A CE2 1 ATOM 262 C CE3 . TRP A 1 62 ? 16.003 49.275 11.440 1.00 10.68 ? 62 TRP A CE3 1 ATOM 263 C CZ2 . TRP A 1 62 ? 17.771 50.169 9.401 1.00 10.13 ? 62 TRP A CZ2 1 ATOM 264 C CZ3 . TRP A 1 62 ? 16.519 48.403 10.527 1.00 12.39 ? 62 TRP A CZ3 1 ATOM 265 C CH2 . TRP A 1 62 ? 17.408 48.850 9.497 1.00 12.06 ? 62 TRP A CH2 1 ATOM 266 N N . LYS A 1 63 ? 14.030 55.353 12.281 1.00 12.62 ? 63 LYS A N 1 ATOM 267 C CA . LYS A 1 63 ? 13.185 56.063 11.306 1.00 13.74 ? 63 LYS A CA 1 ATOM 268 C C . LYS A 1 63 ? 13.190 55.553 9.874 1.00 14.27 ? 63 LYS A C 1 ATOM 269 O O . LYS A 1 63 ? 12.155 55.600 9.166 1.00 14.20 ? 63 LYS A O 1 ATOM 270 C CB . LYS A 1 63 ? 13.545 57.558 11.317 1.00 15.94 ? 63 LYS A CB 1 ATOM 271 C CG . LYS A 1 63 ? 12.871 58.376 12.430 1.00 19.13 ? 63 LYS A CG 1 ATOM 272 C CD . LYS A 1 63 ? 11.372 58.665 12.068 1.00 22.20 ? 63 LYS A CD 1 ATOM 273 C CE . LYS A 1 63 ? 10.393 58.559 13.236 1.00 26.79 ? 63 LYS A CE 1 ATOM 274 N NZ . LYS A 1 63 ? 10.956 58.991 14.564 1.00 28.99 ? 63 LYS A NZ 1 ATOM 275 N N . GLN A 1 64 ? 14.328 55.070 9.422 1.00 12.34 ? 64 GLN A N 1 ATOM 276 C CA . GLN A 1 64 ? 14.422 54.641 8.033 1.00 12.48 ? 64 GLN A CA 1 ATOM 277 C C . GLN A 1 64 ? 14.424 53.134 7.879 1.00 11.65 ? 64 GLN A C 1 ATOM 278 O O . GLN A 1 64 ? 14.720 52.591 6.833 1.00 11.62 ? 64 GLN A O 1 ATOM 279 C CB . GLN A 1 64 ? 15.676 55.263 7.389 1.00 11.99 ? 64 GLN A CB 1 ATOM 280 C CG . GLN A 1 64 ? 15.543 56.802 7.374 1.00 11.74 ? 64 GLN A CG 1 ATOM 281 C CD . GLN A 1 64 ? 16.876 57.500 7.299 1.00 12.70 ? 64 GLN A CD 1 ATOM 282 O OE1 . GLN A 1 64 ? 17.783 57.207 8.080 1.00 12.22 ? 64 GLN A OE1 1 ATOM 283 N NE2 . GLN A 1 64 ? 16.976 58.469 6.368 1.00 11.46 ? 64 GLN A NE2 1 ATOM 284 N N . GLY A 1 65 ? 14.077 52.475 8.982 1.00 12.56 ? 65 GLY A N 1 ATOM 285 C CA . GLY A 1 65 ? 14.010 51.024 8.976 1.00 12.39 ? 65 GLY A CA 1 ATOM 286 C C . GLY A 1 65 ? 12.643 50.470 9.372 1.00 13.12 ? 65 GLY A C 1 ATOM 287 O O . GLY A 1 65 ? 11.628 50.811 8.739 1.00 13.66 ? 65 GLY A O 1 ATOM 288 N N . TRP A 1 66 ? 12.629 49.615 10.390 1.00 12.21 ? 66 TRP A N 1 ATOM 289 C CA . TRP A 1 66 ? 11.384 49.008 10.873 1.00 13.14 ? 66 TRP A CA 1 ATOM 290 C C . TRP A 1 66 ? 11.643 48.585 12.310 1.00 13.14 ? 66 TRP A C 1 ATOM 291 O O . TRP A 1 66 ? 12.773 48.680 12.771 1.00 12.92 ? 66 TRP A O 1 ATOM 292 C CB . TRP A 1 66 ? 11.008 47.802 9.978 1.00 13.46 ? 66 TRP A CB 1 ATOM 293 C CG . TRP A 1 66 ? 11.949 46.622 10.117 1.00 13.18 ? 66 TRP A CG 1 ATOM 294 C CD1 . TRP A 1 66 ? 11.828 45.605 11.016 1.00 12.22 ? 66 TRP A CD1 1 ATOM 295 C CD2 . TRP A 1 66 ? 13.167 46.363 9.399 1.00 13.07 ? 66 TRP A CD2 1 ATOM 296 N NE1 . TRP A 1 66 ? 12.879 44.726 10.939 1.00 14.61 ? 66 TRP A NE1 1 ATOM 297 C CE2 . TRP A 1 66 ? 13.725 45.158 9.943 1.00 12.49 ? 66 TRP A CE2 1 ATOM 298 C CE3 . TRP A 1 66 ? 13.846 47.009 8.341 1.00 13.29 ? 66 TRP A CE3 1 ATOM 299 C CZ2 . TRP A 1 66 ? 14.921 44.591 9.477 1.00 14.23 ? 66 TRP A CZ2 1 ATOM 300 C CZ3 . TRP A 1 66 ? 15.044 46.426 7.872 1.00 13.71 ? 66 TRP A CZ3 1 ATOM 301 C CH2 . TRP A 1 66 ? 15.567 45.239 8.437 1.00 14.56 ? 66 TRP A CH2 1 ATOM 302 N N . ASN A 1 67 ? 10.603 48.144 13.031 1.00 13.65 ? 67 ASN A N 1 ATOM 303 C CA . ASN A 1 67 ? 10.773 47.655 14.429 1.00 14.00 ? 67 ASN A CA 1 ATOM 304 C C . ASN A 1 67 ? 11.403 46.255 14.400 1.00 14.99 ? 67 ASN A C 1 ATOM 305 O O . ASN A 1 67 ? 10.751 45.274 14.076 1.00 14.21 ? 67 ASN A O 1 ATOM 306 C CB . ASN A 1 67 ? 9.415 47.553 15.121 1.00 18.61 ? 67 ASN A CB 1 ATOM 307 C CG . ASN A 1 67 ? 8.846 48.892 15.482 1.00 19.99 ? 67 ASN A CG 1 ATOM 308 O OD1 . ASN A 1 67 ? 9.478 49.934 15.341 1.00 22.67 ? 67 ASN A OD1 1 ATOM 309 N ND2 . ASN A 1 67 ? 7.626 48.872 15.986 1.00 22.66 ? 67 ASN A ND2 1 ATOM 310 N N . ILE A 1 68 ? 12.685 46.165 14.745 1.00 14.13 ? 68 ILE A N 1 ATOM 311 C CA . ILE A 1 68 ? 13.399 44.897 14.652 1.00 14.69 ? 68 ILE A CA 1 ATOM 312 C C . ILE A 1 68 ? 12.961 43.976 15.794 1.00 15.32 ? 68 ILE A C 1 ATOM 313 O O . ILE A 1 68 ? 12.817 44.396 16.944 1.00 15.21 ? 68 ILE A O 1 ATOM 314 C CB . ILE A 1 68 ? 14.969 45.121 14.726 1.00 12.86 ? 68 ILE A CB 1 ATOM 315 C CG1 . ILE A 1 68 ? 15.482 45.991 13.554 1.00 13.05 ? 68 ILE A CG1 1 ATOM 316 C CG2 . ILE A 1 68 ? 15.697 43.731 14.747 1.00 15.06 ? 68 ILE A CG2 1 ATOM 317 C CD1 . ILE A 1 68 ? 16.955 46.469 13.747 1.00 13.31 ? 68 ILE A CD1 1 ATOM 318 N N . LYS A 1 69 ? 12.748 42.707 15.435 1.00 17.22 ? 69 LYS A N 1 ATOM 319 C CA . LYS A 1 69 ? 12.355 41.679 16.401 1.00 19.16 ? 69 LYS A CA 1 ATOM 320 C C . LYS A 1 69 ? 13.413 40.595 16.409 1.00 18.51 ? 69 LYS A C 1 ATOM 321 O O . LYS A 1 69 ? 14.041 40.308 15.396 1.00 19.67 ? 69 LYS A O 1 ATOM 322 C CB . LYS A 1 69 ? 11.020 41.018 16.008 1.00 21.65 ? 69 LYS A CB 1 ATOM 323 C CG . LYS A 1 69 ? 9.841 41.974 15.935 1.00 23.89 ? 69 LYS A CG 1 ATOM 324 C CD . LYS A 1 69 ? 9.631 42.684 17.244 1.00 25.49 ? 69 LYS A CD 1 ATOM 325 C CE . LYS A 1 69 ? 8.470 43.650 17.120 1.00 29.26 ? 69 LYS A CE 1 ATOM 326 N NZ . LYS A 1 69 ? 7.285 42.899 16.607 1.00 30.04 ? 69 LYS A NZ 1 ATOM 327 N N . TYR A 1 70 ? 13.647 40.008 17.566 1.00 18.85 ? 70 TYR A N 1 ATOM 328 C CA . TYR A 1 70 ? 14.594 38.897 17.640 1.00 16.90 ? 70 TYR A CA 1 ATOM 329 C C . TYR A 1 70 ? 14.033 37.797 18.556 1.00 19.70 ? 70 TYR A C 1 ATOM 330 O O . TYR A 1 70 ? 13.099 38.043 19.336 1.00 18.29 ? 70 TYR A O 1 ATOM 331 C CB . TYR A 1 70 ? 16.000 39.380 18.129 1.00 16.32 ? 70 TYR A CB 1 ATOM 332 C CG . TYR A 1 70 ? 16.062 39.960 19.525 1.00 14.30 ? 70 TYR A CG 1 ATOM 333 C CD1 . TYR A 1 70 ? 16.230 39.137 20.670 1.00 14.41 ? 70 TYR A CD1 1 ATOM 334 C CD2 . TYR A 1 70 ? 15.948 41.320 19.712 1.00 14.70 ? 70 TYR A CD2 1 ATOM 335 C CE1 . TYR A 1 70 ? 16.259 39.703 21.974 1.00 12.66 ? 70 TYR A CE1 1 ATOM 336 C CE2 . TYR A 1 70 ? 15.988 41.890 20.966 1.00 15.32 ? 70 TYR A CE2 1 ATOM 337 C CZ . TYR A 1 70 ? 16.122 41.098 22.095 1.00 13.95 ? 70 TYR A CZ 1 ATOM 338 O OH . TYR A 1 70 ? 16.008 41.686 23.343 1.00 14.61 ? 70 TYR A OH 1 ATOM 339 N N . ASP A 1 71 ? 14.576 36.594 18.430 1.00 20.43 ? 71 ASP A N 1 ATOM 340 C CA . ASP A 1 71 ? 14.132 35.496 19.267 1.00 21.63 ? 71 ASP A CA 1 ATOM 341 C C . ASP A 1 71 ? 15.088 35.452 20.448 1.00 21.91 ? 71 ASP A C 1 ATOM 342 O O . ASP A 1 71 ? 16.270 35.188 20.272 1.00 21.25 ? 71 ASP A O 1 ATOM 343 C CB . ASP A 1 71 ? 14.186 34.205 18.455 1.00 23.01 ? 71 ASP A CB 1 ATOM 344 C CG . ASP A 1 71 ? 13.898 32.978 19.299 1.00 26.03 ? 71 ASP A CG 1 ATOM 345 O OD1 . ASP A 1 71 ? 13.539 33.153 20.492 1.00 27.67 ? 71 ASP A OD1 1 ATOM 346 O OD2 . ASP A 1 71 ? 14.047 31.846 18.784 1.00 29.46 ? 71 ASP A OD2 1 ATOM 347 N N . PRO A 1 72 ? 14.582 35.719 21.675 1.00 22.81 ? 72 PRO A N 1 ATOM 348 C CA . PRO A 1 72 ? 15.515 35.689 22.807 1.00 22.53 ? 72 PRO A CA 1 ATOM 349 C C . PRO A 1 72 ? 16.301 34.390 22.943 1.00 22.43 ? 72 PRO A C 1 ATOM 350 O O . PRO A 1 72 ? 17.397 34.397 23.491 1.00 24.27 ? 72 PRO A O 1 ATOM 351 C CB . PRO A 1 72 ? 14.625 35.992 24.035 1.00 23.48 ? 72 PRO A CB 1 ATOM 352 C CG . PRO A 1 72 ? 13.236 35.753 23.565 1.00 24.83 ? 72 PRO A CG 1 ATOM 353 C CD . PRO A 1 72 ? 13.244 36.148 22.105 1.00 22.97 ? 72 PRO A CD 1 ATOM 354 N N . LEU A 1 73 ? 15.783 33.287 22.411 1.00 23.09 ? 73 LEU A N 1 ATOM 355 C CA . LEU A 1 73 ? 16.502 32.003 22.555 1.00 24.20 ? 73 LEU A CA 1 ATOM 356 C C . LEU A 1 73 ? 17.578 31.744 21.506 1.00 23.62 ? 73 LEU A C 1 ATOM 357 O O . LEU A 1 73 ? 18.172 30.674 21.483 1.00 23.45 ? 73 LEU A O 1 ATOM 358 C CB . LEU A 1 73 ? 15.511 30.815 22.586 1.00 25.09 ? 73 LEU A CB 1 ATOM 359 C CG . LEU A 1 73 ? 14.384 30.930 23.632 1.00 26.24 ? 73 LEU A CG 1 ATOM 360 C CD1 . LEU A 1 73 ? 13.368 29.803 23.441 1.00 28.07 ? 73 LEU A CD1 1 ATOM 361 C CD2 . LEU A 1 73 ? 14.979 30.947 25.054 1.00 27.66 ? 73 LEU A CD2 1 ATOM 362 N N . LYS A 1 74 ? 17.837 32.731 20.641 1.00 22.49 ? 74 LYS A N 1 ATOM 363 C CA . LYS A 1 74 ? 18.838 32.558 19.605 1.00 21.64 ? 74 LYS A CA 1 ATOM 364 C C . LYS A 1 74 ? 20.225 32.421 20.244 1.00 21.92 ? 74 LYS A C 1 ATOM 365 O O . LYS A 1 74 ? 21.068 31.627 19.817 1.00 22.12 ? 74 LYS A O 1 ATOM 366 C CB . LYS A 1 74 ? 18.767 33.738 18.606 1.00 21.27 ? 74 LYS A CB 1 ATOM 367 C CG . LYS A 1 74 ? 19.905 33.768 17.601 1.00 22.15 ? 74 LYS A CG 1 ATOM 368 C CD . LYS A 1 74 ? 19.753 34.938 16.619 1.00 22.74 ? 74 LYS A CD 1 ATOM 369 C CE . LYS A 1 74 ? 20.638 34.746 15.368 1.00 23.38 ? 74 LYS A CE 1 ATOM 370 N NZ . LYS A 1 74 ? 20.371 35.735 14.265 1.00 21.93 ? 74 LYS A NZ 1 ATOM 371 N N . TYR A 1 75 ? 20.464 33.204 21.284 1.00 21.54 ? 75 TYR A N 1 ATOM 372 C CA . TYR A 1 75 ? 21.737 33.126 21.973 1.00 21.86 ? 75 TYR A CA 1 ATOM 373 C C . TYR A 1 75 ? 21.512 32.327 23.291 1.00 22.04 ? 75 TYR A C 1 ATOM 374 O O . TYR A 1 75 ? 20.480 32.473 23.940 1.00 23.99 ? 75 TYR A O 1 ATOM 375 C CB . TYR A 1 75 ? 22.269 34.570 22.180 1.00 21.56 ? 75 TYR A CB 1 ATOM 376 C CG . TYR A 1 75 ? 22.663 35.243 20.854 1.00 19.29 ? 75 TYR A CG 1 ATOM 377 C CD1 . TYR A 1 75 ? 23.716 34.725 20.091 1.00 21.21 ? 75 TYR A CD1 1 ATOM 378 C CD2 . TYR A 1 75 ? 21.914 36.297 20.311 1.00 19.19 ? 75 TYR A CD2 1 ATOM 379 C CE1 . TYR A 1 75 ? 24.029 35.222 18.802 1.00 21.65 ? 75 TYR A CE1 1 ATOM 380 C CE2 . TYR A 1 75 ? 22.198 36.802 19.034 1.00 20.58 ? 75 TYR A CE2 1 ATOM 381 C CZ . TYR A 1 75 ? 23.267 36.247 18.277 1.00 22.30 ? 75 TYR A CZ 1 ATOM 382 O OH . TYR A 1 75 ? 23.535 36.657 16.971 1.00 24.29 ? 75 TYR A OH 1 ATOM 383 N N . ASN A 1 76 ? 22.459 31.446 23.621 1.00 23.22 ? 76 ASN A N 1 ATOM 384 C CA . ASN A 1 76 ? 22.412 30.582 24.806 1.00 23.89 ? 76 ASN A CA 1 ATOM 385 C C . ASN A 1 76 ? 23.827 30.276 25.262 1.00 24.52 ? 76 ASN A C 1 ATOM 386 O O . ASN A 1 76 ? 24.779 30.690 24.605 1.00 23.64 ? 76 ASN A O 1 ATOM 387 C CB . ASN A 1 76 ? 21.695 29.268 24.501 1.00 23.04 ? 76 ASN A CB 1 ATOM 388 C CG . ASN A 1 76 ? 22.289 28.547 23.325 1.00 23.97 ? 76 ASN A CG 1 ATOM 389 O OD1 . ASN A 1 76 ? 23.477 28.212 23.294 1.00 24.90 ? 76 ASN A OD1 1 ATOM 390 N ND2 . ASN A 1 76 ? 21.455 28.303 22.327 1.00 27.82 ? 76 ASN A ND2 1 ATOM 391 N N . ALA A 1 77 ? 23.986 29.512 26.350 1.00 25.13 ? 77 ALA A N 1 ATOM 392 C CA . ALA A 1 77 ? 25.328 29.238 26.885 1.00 26.66 ? 77 ALA A CA 1 ATOM 393 C C . ALA A 1 77 ? 26.307 28.726 25.866 1.00 27.30 ? 77 ALA A C 1 ATOM 394 O O . ALA A 1 77 ? 27.496 29.037 25.935 1.00 27.62 ? 77 ALA A O 1 ATOM 395 C CB . ALA A 1 77 ? 25.265 28.263 28.074 1.00 27.13 ? 77 ALA A CB 1 ATOM 396 N N . HIS A 1 78 ? 25.804 27.967 24.899 1.00 28.89 ? 78 HIS A N 1 ATOM 397 C CA . HIS A 1 78 ? 26.669 27.397 23.868 1.00 30.01 ? 78 HIS A CA 1 ATOM 398 C C . HIS A 1 78 ? 26.766 28.236 22.585 1.00 28.82 ? 78 HIS A C 1 ATOM 399 O O . HIS A 1 78 ? 27.405 27.829 21.598 1.00 28.84 ? 78 HIS A O 1 ATOM 400 C CB . HIS A 1 78 ? 26.174 25.986 23.548 1.00 33.16 ? 78 HIS A CB 1 ATOM 401 C CG . HIS A 1 78 ? 25.998 25.148 24.771 1.00 36.51 ? 78 HIS A CG 1 ATOM 402 N ND1 . HIS A 1 78 ? 27.066 24.601 25.453 1.00 37.65 ? 78 HIS A ND1 1 ATOM 403 C CD2 . HIS A 1 78 ? 24.896 24.891 25.519 1.00 37.71 ? 78 HIS A CD2 1 ATOM 404 C CE1 . HIS A 1 78 ? 26.630 24.050 26.575 1.00 39.08 ? 78 HIS A CE1 1 ATOM 405 N NE2 . HIS A 1 78 ? 25.318 24.213 26.640 1.00 39.47 ? 78 HIS A NE2 1 ATOM 406 N N . HIS A 1 79 ? 26.159 29.417 22.605 1.00 25.32 ? 79 HIS A N 1 ATOM 407 C CA . HIS A 1 79 ? 26.200 30.268 21.422 1.00 22.61 ? 79 HIS A CA 1 ATOM 408 C C . HIS A 1 79 ? 25.911 31.675 21.905 1.00 19.29 ? 79 HIS A C 1 ATOM 409 O O . HIS A 1 79 ? 24.769 32.128 21.917 1.00 17.86 ? 79 HIS A O 1 ATOM 410 C CB . HIS A 1 79 ? 25.127 29.808 20.417 1.00 22.45 ? 79 HIS A CB 1 ATOM 411 C CG . HIS A 1 79 ? 25.166 30.530 19.101 1.00 24.06 ? 79 HIS A CG 1 ATOM 412 N ND1 . HIS A 1 79 ? 26.207 30.395 18.204 1.00 25.13 ? 79 HIS A ND1 1 ATOM 413 C CD2 . HIS A 1 79 ? 24.316 31.430 18.561 1.00 23.22 ? 79 HIS A CD2 1 ATOM 414 C CE1 . HIS A 1 79 ? 25.994 31.186 17.164 1.00 24.13 ? 79 HIS A CE1 1 ATOM 415 N NE2 . HIS A 1 79 ? 24.851 31.827 17.357 1.00 25.85 ? 79 HIS A NE2 1 ATOM 416 N N . LYS A 1 80 ? 26.973 32.330 22.352 1.00 18.20 ? 80 LYS A N 1 ATOM 417 C CA . LYS A 1 80 ? 26.853 33.669 22.897 1.00 17.75 ? 80 LYS A CA 1 ATOM 418 C C . LYS A 1 80 ? 27.084 34.713 21.826 1.00 16.25 ? 80 LYS A C 1 ATOM 419 O O . LYS A 1 80 ? 27.737 34.449 20.809 1.00 17.31 ? 80 LYS A O 1 ATOM 420 C CB . LYS A 1 80 ? 27.905 33.886 23.978 1.00 18.12 ? 80 LYS A CB 1 ATOM 421 C CG . LYS A 1 80 ? 27.815 32.872 25.131 1.00 19.43 ? 80 LYS A CG 1 ATOM 422 C CD . LYS A 1 80 ? 29.049 32.933 25.993 1.00 22.46 ? 80 LYS A CD 1 ATOM 423 C CE . LYS A 1 80 ? 29.025 34.165 26.905 1.00 24.13 ? 80 LYS A CE 1 ATOM 424 N NZ . LYS A 1 80 ? 29.867 33.887 28.157 1.00 26.21 ? 80 LYS A NZ 1 ATOM 425 N N . LEU A 1 81 ? 26.525 35.885 22.060 1.00 13.89 ? 81 LEU A N 1 ATOM 426 C CA . LEU A 1 81 ? 26.751 37.019 21.167 1.00 12.33 ? 81 LEU A CA 1 ATOM 427 C C . LEU A 1 81 ? 28.049 37.716 21.664 1.00 12.01 ? 81 LEU A C 1 ATOM 428 O O . LEU A 1 81 ? 28.095 38.154 22.824 1.00 11.78 ? 81 LEU A O 1 ATOM 429 C CB . LEU A 1 81 ? 25.579 38.020 21.265 1.00 12.36 ? 81 LEU A CB 1 ATOM 430 C CG . LEU A 1 81 ? 25.622 39.306 20.394 1.00 10.94 ? 81 LEU A CG 1 ATOM 431 C CD1 . LEU A 1 81 ? 25.736 38.949 18.855 1.00 9.67 ? 81 LEU A CD1 1 ATOM 432 C CD2 . LEU A 1 81 ? 24.377 40.187 20.705 1.00 12.24 ? 81 LEU A CD2 1 ATOM 433 N N . LYS A 1 82 ? 29.087 37.825 20.829 1.00 10.04 ? 82 LYS A N 1 ATOM 434 C CA . LYS A 1 82 ? 30.352 38.467 21.185 1.00 11.34 ? 82 LYS A CA 1 ATOM 435 C C . LYS A 1 82 ? 30.233 39.883 20.657 1.00 11.35 ? 82 LYS A C 1 ATOM 436 O O . LYS A 1 82 ? 29.961 40.076 19.510 1.00 13.26 ? 82 LYS A O 1 ATOM 437 C CB . LYS A 1 82 ? 31.533 37.728 20.531 1.00 14.18 ? 82 LYS A CB 1 ATOM 438 C CG . LYS A 1 82 ? 31.633 36.262 20.940 1.00 17.84 ? 82 LYS A CG 1 ATOM 439 C CD . LYS A 1 82 ? 32.661 35.438 20.143 1.00 22.88 ? 82 LYS A CD 1 ATOM 440 C CE . LYS A 1 82 ? 32.465 33.953 20.434 1.00 24.27 ? 82 LYS A CE 1 ATOM 441 N NZ . LYS A 1 82 ? 32.958 33.037 19.362 1.00 27.64 ? 82 LYS A NZ 1 ATOM 442 N N . VAL A 1 83 ? 30.420 40.857 21.545 1.00 9.67 ? 83 VAL A N 1 ATOM 443 C CA . VAL A 1 83 ? 30.272 42.269 21.207 1.00 8.84 ? 83 VAL A CA 1 ATOM 444 C C . VAL A 1 83 ? 31.579 43.005 21.392 1.00 9.92 ? 83 VAL A C 1 ATOM 445 O O . VAL A 1 83 ? 32.168 42.935 22.469 1.00 9.49 ? 83 VAL A O 1 ATOM 446 C CB . VAL A 1 83 ? 29.208 42.915 22.117 1.00 10.94 ? 83 VAL A CB 1 ATOM 447 C CG1 . VAL A 1 83 ? 28.987 44.413 21.721 1.00 11.42 ? 83 VAL A CG1 1 ATOM 448 C CG2 . VAL A 1 83 ? 27.850 42.121 21.961 1.00 10.38 ? 83 VAL A CG2 1 ATOM 449 N N . PHE A 1 84 ? 32.024 43.673 20.333 1.00 9.56 ? 84 PHE A N 1 ATOM 450 C CA . PHE A 1 84 ? 33.236 44.472 20.334 1.00 10.18 ? 84 PHE A CA 1 ATOM 451 C C . PHE A 1 84 ? 32.859 45.936 20.250 1.00 10.20 ? 84 PHE A C 1 ATOM 452 O O . PHE A 1 84 ? 32.328 46.371 19.213 1.00 9.86 ? 84 PHE A O 1 ATOM 453 C CB . PHE A 1 84 ? 34.120 44.103 19.116 1.00 11.35 ? 84 PHE A CB 1 ATOM 454 C CG . PHE A 1 84 ? 34.784 42.753 19.252 1.00 12.75 ? 84 PHE A CG 1 ATOM 455 C CD1 . PHE A 1 84 ? 35.881 42.554 20.096 1.00 14.58 ? 84 PHE A CD1 1 ATOM 456 C CD2 . PHE A 1 84 ? 34.281 41.674 18.579 1.00 11.99 ? 84 PHE A CD2 1 ATOM 457 C CE1 . PHE A 1 84 ? 36.455 41.275 20.244 1.00 13.38 ? 84 PHE A CE1 1 ATOM 458 C CE2 . PHE A 1 84 ? 34.862 40.386 18.728 1.00 14.54 ? 84 PHE A CE2 1 ATOM 459 C CZ . PHE A 1 84 ? 35.937 40.212 19.556 1.00 12.70 ? 84 PHE A CZ 1 ATOM 460 N N . VAL A 1 85 ? 33.178 46.668 21.329 1.00 8.93 ? 85 VAL A N 1 ATOM 461 C CA . VAL A 1 85 ? 32.937 48.101 21.396 1.00 8.82 ? 85 VAL A CA 1 ATOM 462 C C . VAL A 1 85 ? 34.257 48.741 21.024 1.00 7.40 ? 85 VAL A C 1 ATOM 463 O O . VAL A 1 85 ? 35.257 48.561 21.748 1.00 9.24 ? 85 VAL A O 1 ATOM 464 C CB . VAL A 1 85 ? 32.461 48.487 22.808 1.00 8.94 ? 85 VAL A CB 1 ATOM 465 C CG1 . VAL A 1 85 ? 32.212 50.015 22.911 1.00 10.18 ? 85 VAL A CG1 1 ATOM 466 C CG2 . VAL A 1 85 ? 31.129 47.716 23.099 1.00 10.53 ? 85 VAL A CG2 1 ATOM 467 N N . VAL A 1 86 ? 34.225 49.501 19.910 1.00 7.79 ? 86 VAL A N 1 ATOM 468 C CA . VAL A 1 86 ? 35.439 50.048 19.322 1.00 6.98 ? 86 VAL A CA 1 ATOM 469 C C . VAL A 1 86 ? 35.511 51.561 19.425 1.00 8.42 ? 86 VAL A C 1 ATOM 470 O O . VAL A 1 86 ? 34.866 52.266 18.668 1.00 7.38 ? 86 VAL A O 1 ATOM 471 C CB . VAL A 1 86 ? 35.544 49.547 17.820 1.00 6.85 ? 86 VAL A CB 1 ATOM 472 C CG1 . VAL A 1 86 ? 36.843 50.034 17.191 1.00 7.80 ? 86 VAL A CG1 1 ATOM 473 C CG2 . VAL A 1 86 ? 35.485 48.005 17.762 1.00 6.77 ? 86 VAL A CG2 1 ATOM 474 N N . PRO A 1 87 ? 36.306 52.060 20.384 1.00 8.86 ? 87 PRO A N 1 ATOM 475 C CA . PRO A 1 87 ? 36.443 53.520 20.562 1.00 9.90 ? 87 PRO A CA 1 ATOM 476 C C . PRO A 1 87 ? 37.161 54.158 19.352 1.00 8.63 ? 87 PRO A C 1 ATOM 477 O O . PRO A 1 87 ? 38.127 53.601 18.799 1.00 8.91 ? 87 PRO A O 1 ATOM 478 C CB . PRO A 1 87 ? 37.257 53.650 21.855 1.00 8.83 ? 87 PRO A CB 1 ATOM 479 C CG . PRO A 1 87 ? 36.993 52.318 22.585 1.00 11.97 ? 87 PRO A CG 1 ATOM 480 C CD . PRO A 1 87 ? 37.008 51.319 21.453 1.00 9.54 ? 87 PRO A CD 1 ATOM 481 N N . HIS A 1 88 ? 36.695 55.334 18.968 1.00 7.66 ? 88 HIS A N 1 ATOM 482 C CA . HIS A 1 88 ? 37.256 56.013 17.800 1.00 7.22 ? 88 HIS A CA 1 ATOM 483 C C . HIS A 1 88 ? 37.027 57.504 17.884 1.00 9.01 ? 88 HIS A C 1 ATOM 484 O O . HIS A 1 88 ? 36.150 57.985 18.637 1.00 8.71 ? 88 HIS A O 1 ATOM 485 C CB . HIS A 1 88 ? 36.641 55.387 16.491 1.00 7.88 ? 88 HIS A CB 1 ATOM 486 C CG . HIS A 1 88 ? 35.198 55.740 16.220 1.00 8.13 ? 88 HIS A CG 1 ATOM 487 N ND1 . HIS A 1 88 ? 34.822 56.811 15.417 1.00 8.69 ? 88 HIS A ND1 1 ATOM 488 C CD2 . HIS A 1 88 ? 34.036 55.181 16.660 1.00 7.92 ? 88 HIS A CD2 1 ATOM 489 C CE1 . HIS A 1 88 ? 33.506 56.877 15.369 1.00 8.78 ? 88 HIS A CE1 1 ATOM 490 N NE2 . HIS A 1 88 ? 33.008 55.904 16.114 1.00 8.23 ? 88 HIS A NE2 1 ATOM 491 N N . SER A 1 89 ? 37.769 58.246 17.071 1.00 7.89 ? 89 SER A N 1 ATOM 492 C CA . SER A 1 89 ? 37.646 59.729 17.055 1.00 7.95 ? 89 SER A CA 1 ATOM 493 C C . SER A 1 89 ? 37.821 60.180 15.643 1.00 8.13 ? 89 SER A C 1 ATOM 494 O O . SER A 1 89 ? 38.911 60.017 15.100 1.00 6.44 ? 89 SER A O 1 ATOM 495 C CB . SER A 1 89 ? 38.715 60.332 17.969 1.00 10.39 ? 89 SER A CB 1 ATOM 496 O OG . SER A 1 89 ? 38.657 61.742 17.931 1.00 7.86 ? 89 SER A OG 1 ATOM 497 N N . HIS A 1 90 ? 36.785 60.724 15.015 1.00 7.23 ? 90 HIS A N 1 ATOM 498 C CA . HIS A 1 90 ? 36.913 61.170 13.634 1.00 8.15 ? 90 HIS A CA 1 ATOM 499 C C . HIS A 1 90 ? 37.574 62.559 13.573 1.00 8.09 ? 90 HIS A C 1 ATOM 500 O O . HIS A 1 90 ? 37.009 63.551 14.036 1.00 8.64 ? 90 HIS A O 1 ATOM 501 C CB . HIS A 1 90 ? 35.517 61.181 13.013 1.00 7.68 ? 90 HIS A CB 1 ATOM 502 C CG . HIS A 1 90 ? 35.494 61.558 11.557 1.00 6.77 ? 90 HIS A CG 1 ATOM 503 N ND1 . HIS A 1 90 ? 36.014 60.746 10.571 1.00 7.32 ? 90 HIS A ND1 1 ATOM 504 C CD2 . HIS A 1 90 ? 34.980 62.639 10.921 1.00 5.88 ? 90 HIS A CD2 1 ATOM 505 C CE1 . HIS A 1 90 ? 35.799 61.307 9.389 1.00 8.01 ? 90 HIS A CE1 1 ATOM 506 N NE2 . HIS A 1 90 ? 35.181 62.461 9.575 1.00 6.58 ? 90 HIS A NE2 1 ATOM 507 N N . ASN A 1 91 ? 38.746 62.623 12.956 1.00 8.23 ? 91 ASN A N 1 ATOM 508 C CA . ASN A 1 91 ? 39.514 63.879 12.884 1.00 6.67 ? 91 ASN A CA 1 ATOM 509 C C . ASN A 1 91 ? 39.680 64.351 11.452 1.00 9.90 ? 91 ASN A C 1 ATOM 510 O O . ASN A 1 91 ? 40.520 63.807 10.708 1.00 12.79 ? 91 ASN A O 1 ATOM 511 C CB . ASN A 1 91 ? 40.895 63.643 13.532 1.00 8.35 ? 91 ASN A CB 1 ATOM 512 C CG . ASN A 1 91 ? 40.823 63.575 15.045 1.00 9.40 ? 91 ASN A CG 1 ATOM 513 O OD1 . ASN A 1 91 ? 41.379 64.415 15.747 1.00 11.74 ? 91 ASN A OD1 1 ATOM 514 N ND2 . ASN A 1 91 ? 40.165 62.546 15.568 1.00 8.09 ? 91 ASN A ND2 1 ATOM 515 N N . ASP A 1 92 ? 38.939 65.382 11.103 1.00 6.38 ? 92 ASP A N 1 ATOM 516 C CA . ASP A 1 92 ? 39.055 65.920 9.736 1.00 7.98 ? 92 ASP A CA 1 ATOM 517 C C . ASP A 1 92 ? 40.275 66.774 9.603 1.00 8.47 ? 92 ASP A C 1 ATOM 518 O O . ASP A 1 92 ? 40.485 67.705 10.400 1.00 8.87 ? 92 ASP A O 1 ATOM 519 C CB . ASP A 1 92 ? 37.836 66.805 9.471 1.00 6.97 ? 92 ASP A CB 1 ATOM 520 C CG . ASP A 1 92 ? 36.548 65.995 9.532 1.00 9.41 ? 92 ASP A CG 1 ATOM 521 O OD1 . ASP A 1 92 ? 36.334 65.156 8.645 1.00 9.05 ? 92 ASP A OD1 1 ATOM 522 O OD2 . ASP A 1 92 ? 35.808 66.247 10.519 1.00 10.78 ? 92 ASP A OD2 1 ATOM 523 N N . PRO A 1 93 ? 41.090 66.491 8.545 1.00 6.81 ? 93 PRO A N 1 ATOM 524 C CA . PRO A 1 93 ? 42.322 67.294 8.264 1.00 10.87 ? 93 PRO A CA 1 ATOM 525 C C . PRO A 1 93 ? 41.883 68.571 7.462 1.00 9.33 ? 93 PRO A C 1 ATOM 526 O O . PRO A 1 93 ? 42.191 68.765 6.266 1.00 8.68 ? 93 PRO A O 1 ATOM 527 C CB . PRO A 1 93 ? 43.176 66.345 7.415 1.00 10.49 ? 93 PRO A CB 1 ATOM 528 C CG . PRO A 1 93 ? 42.644 64.953 7.751 1.00 10.84 ? 93 PRO A CG 1 ATOM 529 C CD . PRO A 1 93 ? 41.113 65.215 7.791 1.00 8.81 ? 93 PRO A CD 1 ATOM 530 N N . GLY A 1 94 ? 41.062 69.357 8.133 1.00 10.99 ? 94 GLY A N 1 ATOM 531 C CA . GLY A 1 94 ? 40.487 70.571 7.599 1.00 8.64 ? 94 GLY A CA 1 ATOM 532 C C . GLY A 1 94 ? 38.988 70.389 7.404 1.00 8.12 ? 94 GLY A C 1 ATOM 533 O O . GLY A 1 94 ? 38.562 69.333 6.789 1.00 10.09 ? 94 GLY A O 1 ATOM 534 N N . TRP A 1 95 ? 38.193 71.369 7.888 1.00 8.82 ? 95 TRP A N 1 ATOM 535 C CA . TRP A 1 95 ? 36.770 71.431 7.655 1.00 8.48 ? 95 TRP A CA 1 ATOM 536 C C . TRP A 1 95 ? 36.285 72.836 8.109 1.00 10.05 ? 95 TRP A C 1 ATOM 537 O O . TRP A 1 95 ? 36.221 73.712 7.275 1.00 9.32 ? 95 TRP A O 1 ATOM 538 C CB . TRP A 1 95 ? 35.971 70.259 8.306 1.00 7.19 ? 95 TRP A CB 1 ATOM 539 C CG . TRP A 1 95 ? 34.474 70.408 7.931 1.00 8.19 ? 95 TRP A CG 1 ATOM 540 C CD1 . TRP A 1 95 ? 33.936 70.739 6.692 1.00 8.15 ? 95 TRP A CD1 1 ATOM 541 C CD2 . TRP A 1 95 ? 33.387 70.231 8.812 1.00 10.87 ? 95 TRP A CD2 1 ATOM 542 N NE1 . TRP A 1 95 ? 32.561 70.779 6.785 1.00 8.53 ? 95 TRP A NE1 1 ATOM 543 C CE2 . TRP A 1 95 ? 32.207 70.460 8.076 1.00 7.32 ? 95 TRP A CE2 1 ATOM 544 C CE3 . TRP A 1 95 ? 33.288 69.883 10.168 1.00 8.20 ? 95 TRP A CE3 1 ATOM 545 C CZ2 . TRP A 1 95 ? 30.920 70.341 8.678 1.00 9.74 ? 95 TRP A CZ2 1 ATOM 546 C CZ3 . TRP A 1 95 ? 32.008 69.764 10.755 1.00 11.86 ? 95 TRP A CZ3 1 ATOM 547 C CH2 . TRP A 1 95 ? 30.856 69.996 9.987 1.00 7.92 ? 95 TRP A CH2 1 ATOM 548 N N . ILE A 1 96 ? 35.898 72.965 9.374 1.00 10.75 ? 96 ILE A N 1 ATOM 549 C CA . ILE A 1 96 ? 35.458 74.252 9.950 1.00 13.78 ? 96 ILE A CA 1 ATOM 550 C C . ILE A 1 96 ? 36.713 75.020 10.340 1.00 15.05 ? 96 ILE A C 1 ATOM 551 O O . ILE A 1 96 ? 36.612 76.213 10.620 1.00 15.94 ? 96 ILE A O 1 ATOM 552 C CB . ILE A 1 96 ? 34.619 74.074 11.261 1.00 15.45 ? 96 ILE A CB 1 ATOM 553 C CG1 . ILE A 1 96 ? 33.335 73.315 10.976 1.00 18.18 ? 96 ILE A CG1 1 ATOM 554 C CG2 . ILE A 1 96 ? 34.335 75.430 11.908 1.00 16.61 ? 96 ILE A CG2 1 ATOM 555 C CD1 . ILE A 1 96 ? 32.693 73.754 9.755 1.00 16.04 ? 96 ILE A CD1 1 ATOM 556 N N . GLN A 1 97 ? 37.846 74.335 10.472 1.00 11.10 ? 97 GLN A N 1 ATOM 557 C CA . GLN A 1 97 ? 39.142 74.947 10.856 1.00 13.03 ? 97 GLN A CA 1 ATOM 558 C C . GLN A 1 97 ? 40.141 74.328 9.897 1.00 11.73 ? 97 GLN A C 1 ATOM 559 O O . GLN A 1 97 ? 39.812 73.349 9.219 1.00 11.29 ? 97 GLN A O 1 ATOM 560 C CB . GLN A 1 97 ? 39.541 74.595 12.332 1.00 12.54 ? 97 GLN A CB 1 ATOM 561 C CG . GLN A 1 97 ? 38.509 75.025 13.410 1.00 18.62 ? 97 GLN A CG 1 ATOM 562 C CD . GLN A 1 97 ? 39.022 74.851 14.861 1.00 21.09 ? 97 GLN A CD 1 ATOM 563 O OE1 . GLN A 1 97 ? 40.161 75.203 15.184 1.00 23.34 ? 97 GLN A OE1 1 ATOM 564 N NE2 . GLN A 1 97 ? 38.191 74.266 15.725 1.00 24.62 ? 97 GLN A NE2 1 ATOM 565 N N . THR A 1 98 ? 41.360 74.869 9.792 1.00 11.39 ? 98 THR A N 1 ATOM 566 C CA . THR A 1 98 ? 42.362 74.301 8.918 1.00 10.25 ? 98 THR A CA 1 ATOM 567 C C . THR A 1 98 ? 42.996 73.120 9.660 1.00 10.63 ? 98 THR A C 1 ATOM 568 O O . THR A 1 98 ? 42.772 72.894 10.851 1.00 8.88 ? 98 THR A O 1 ATOM 569 C CB . THR A 1 98 ? 43.466 75.316 8.686 1.00 11.67 ? 98 THR A CB 1 ATOM 570 O OG1 . THR A 1 98 ? 44.072 75.622 9.973 1.00 12.47 ? 98 THR A OG1 1 ATOM 571 C CG2 . THR A 1 98 ? 42.902 76.628 8.128 1.00 9.12 ? 98 THR A CG2 1 ATOM 572 N N . PHE A 1 99 ? 43.781 72.350 8.952 1.00 8.89 ? 99 PHE A N 1 ATOM 573 C CA . PHE A 1 99 ? 44.498 71.230 9.575 1.00 11.18 ? 99 PHE A CA 1 ATOM 574 C C . PHE A 1 99 ? 45.288 71.702 10.830 1.00 12.41 ? 99 PHE A C 1 ATOM 575 O O . PHE A 1 99 ? 45.228 71.086 11.905 1.00 12.03 ? 99 PHE A O 1 ATOM 576 C CB . PHE A 1 99 ? 45.488 70.748 8.550 1.00 9.70 ? 99 PHE A CB 1 ATOM 577 C CG . PHE A 1 99 ? 46.351 69.616 9.041 1.00 9.45 ? 99 PHE A CG 1 ATOM 578 C CD1 . PHE A 1 99 ? 45.944 68.260 8.899 1.00 9.31 ? 99 PHE A CD1 1 ATOM 579 C CD2 . PHE A 1 99 ? 47.592 69.897 9.622 1.00 11.27 ? 99 PHE A CD2 1 ATOM 580 C CE1 . PHE A 1 99 ? 46.802 67.194 9.332 1.00 8.82 ? 99 PHE A CE1 1 ATOM 581 C CE2 . PHE A 1 99 ? 48.424 68.855 10.056 1.00 9.31 ? 99 PHE A CE2 1 ATOM 582 C CZ . PHE A 1 99 ? 48.041 67.521 9.909 1.00 9.96 ? 99 PHE A CZ 1 ATOM 583 N N . GLU A 1 100 ? 46.057 72.795 10.664 1.00 10.89 ? 100 GLU A N 1 ATOM 584 C CA . GLU A 1 100 ? 46.871 73.221 11.803 1.00 11.58 ? 100 GLU A CA 1 ATOM 585 C C . GLU A 1 100 ? 46.061 73.747 12.954 1.00 12.57 ? 100 GLU A C 1 ATOM 586 O O . GLU A 1 100 ? 46.383 73.474 14.127 1.00 12.86 ? 100 GLU A O 1 ATOM 587 C CB . GLU A 1 100 ? 47.937 74.240 11.368 1.00 10.90 ? 100 GLU A CB 1 ATOM 588 C CG . GLU A 1 100 ? 49.000 74.599 12.446 1.00 12.75 ? 100 GLU A CG 1 ATOM 589 C CD . GLU A 1 100 ? 49.871 73.451 12.900 1.00 16.52 ? 100 GLU A CD 1 ATOM 590 O OE1 . GLU A 1 100 ? 50.001 72.437 12.168 1.00 15.91 ? 100 GLU A OE1 1 ATOM 591 O OE2 . GLU A 1 100 ? 50.483 73.595 14.010 1.00 18.06 ? 100 GLU A OE2 1 ATOM 592 N N . GLU A 1 101 ? 44.974 74.468 12.657 1.00 10.81 ? 101 GLU A N 1 ATOM 593 C CA . GLU A 1 101 ? 44.135 74.925 13.749 1.00 11.32 ? 101 GLU A CA 1 ATOM 594 C C . GLU A 1 101 ? 43.522 73.724 14.538 1.00 11.18 ? 101 GLU A C 1 ATOM 595 O O . GLU A 1 101 ? 43.489 73.717 15.762 1.00 10.44 ? 101 GLU A O 1 ATOM 596 C CB . GLU A 1 101 ? 42.987 75.820 13.229 1.00 13.79 ? 101 GLU A CB 1 ATOM 597 C CG . GLU A 1 101 ? 43.457 77.198 12.704 1.00 14.65 ? 101 GLU A CG 1 ATOM 598 C CD . GLU A 1 101 ? 42.385 77.983 11.927 1.00 19.77 ? 101 GLU A CD 1 ATOM 599 O OE1 . GLU A 1 101 ? 41.404 77.409 11.409 1.00 15.68 ? 101 GLU A OE1 1 ATOM 600 O OE2 . GLU A 1 101 ? 42.548 79.228 11.805 1.00 21.00 ? 101 GLU A OE2 1 ATOM 601 N N . TYR A 1 102 ? 42.989 72.715 13.842 1.00 10.62 ? 102 TYR A N 1 ATOM 602 C CA . TYR A 1 102 ? 42.418 71.549 14.566 1.00 10.50 ? 102 TYR A CA 1 ATOM 603 C C . TYR A 1 102 ? 43.511 70.779 15.324 1.00 8.62 ? 102 TYR A C 1 ATOM 604 O O . TYR A 1 102 ? 43.274 70.256 16.368 1.00 11.88 ? 102 TYR A O 1 ATOM 605 C CB . TYR A 1 102 ? 41.776 70.535 13.607 1.00 11.10 ? 102 TYR A CB 1 ATOM 606 C CG . TYR A 1 102 ? 40.368 70.850 13.143 1.00 6.41 ? 102 TYR A CG 1 ATOM 607 C CD1 . TYR A 1 102 ? 39.339 71.071 14.008 1.00 10.21 ? 102 TYR A CD1 1 ATOM 608 C CD2 . TYR A 1 102 ? 40.048 70.754 11.763 1.00 10.47 ? 102 TYR A CD2 1 ATOM 609 C CE1 . TYR A 1 102 ? 38.006 71.177 13.546 1.00 10.01 ? 102 TYR A CE1 1 ATOM 610 C CE2 . TYR A 1 102 ? 38.737 70.823 11.285 1.00 9.05 ? 102 TYR A CE2 1 ATOM 611 C CZ . TYR A 1 102 ? 37.715 71.036 12.204 1.00 10.98 ? 102 TYR A CZ 1 ATOM 612 O OH . TYR A 1 102 ? 36.406 71.077 11.793 1.00 11.92 ? 102 TYR A OH 1 ATOM 613 N N . TYR A 1 103 ? 44.694 70.700 14.754 1.00 8.71 ? 103 TYR A N 1 ATOM 614 C CA . TYR A 1 103 ? 45.754 69.982 15.444 1.00 11.24 ? 103 TYR A CA 1 ATOM 615 C C . TYR A 1 103 ? 46.058 70.694 16.747 1.00 11.88 ? 103 TYR A C 1 ATOM 616 O O . TYR A 1 103 ? 46.225 70.056 17.770 1.00 11.26 ? 103 TYR A O 1 ATOM 617 C CB . TYR A 1 103 ? 47.023 69.941 14.594 1.00 10.95 ? 103 TYR A CB 1 ATOM 618 C CG . TYR A 1 103 ? 48.178 69.338 15.308 1.00 12.52 ? 103 TYR A CG 1 ATOM 619 C CD1 . TYR A 1 103 ? 48.202 67.980 15.580 1.00 12.68 ? 103 TYR A CD1 1 ATOM 620 C CD2 . TYR A 1 103 ? 49.243 70.153 15.796 1.00 12.72 ? 103 TYR A CD2 1 ATOM 621 C CE1 . TYR A 1 103 ? 49.221 67.408 16.328 1.00 13.95 ? 103 TYR A CE1 1 ATOM 622 C CE2 . TYR A 1 103 ? 50.277 69.573 16.551 1.00 13.74 ? 103 TYR A CE2 1 ATOM 623 C CZ . TYR A 1 103 ? 50.249 68.218 16.813 1.00 13.94 ? 103 TYR A CZ 1 ATOM 624 O OH . TYR A 1 103 ? 51.239 67.674 17.641 1.00 18.71 ? 103 TYR A OH 1 ATOM 625 N N . GLN A 1 104 ? 46.116 72.032 16.692 1.00 12.93 ? 104 GLN A N 1 ATOM 626 C CA . GLN A 1 104 ? 46.452 72.790 17.903 1.00 13.50 ? 104 GLN A CA 1 ATOM 627 C C . GLN A 1 104 ? 45.345 72.803 18.928 1.00 14.78 ? 104 GLN A C 1 ATOM 628 O O . GLN A 1 104 ? 45.599 72.651 20.109 1.00 16.74 ? 104 GLN A O 1 ATOM 629 C CB . GLN A 1 104 ? 46.789 74.249 17.560 1.00 13.74 ? 104 GLN A CB 1 ATOM 630 C CG . GLN A 1 104 ? 48.153 74.512 16.898 1.00 12.92 ? 104 GLN A CG 1 ATOM 631 C CD . GLN A 1 104 ? 49.349 73.922 17.694 1.00 15.37 ? 104 GLN A CD 1 ATOM 632 O OE1 . GLN A 1 104 ? 49.336 73.942 18.906 1.00 15.34 ? 104 GLN A OE1 1 ATOM 633 N NE2 . GLN A 1 104 ? 50.351 73.408 17.002 1.00 14.55 ? 104 GLN A NE2 1 ATOM 634 N N . HIS A 1 105 ? 44.116 72.943 18.468 1.00 14.50 ? 105 HIS A N 1 ATOM 635 C CA . HIS A 1 105 ? 42.995 73.041 19.382 1.00 16.33 ? 105 HIS A CA 1 ATOM 636 C C . HIS A 1 105 ? 42.422 71.715 19.843 1.00 15.22 ? 105 HIS A C 1 ATOM 637 O O . HIS A 1 105 ? 41.891 71.626 20.953 1.00 16.06 ? 105 HIS A O 1 ATOM 638 C CB . HIS A 1 105 ? 41.876 73.834 18.713 1.00 17.98 ? 105 HIS A CB 1 ATOM 639 C CG . HIS A 1 105 ? 42.302 75.192 18.245 1.00 21.00 ? 105 HIS A CG 1 ATOM 640 N ND1 . HIS A 1 105 ? 41.675 75.851 17.210 1.00 22.13 ? 105 HIS A ND1 1 ATOM 641 C CD2 . HIS A 1 105 ? 43.319 75.996 18.645 1.00 21.90 ? 105 HIS A CD2 1 ATOM 642 C CE1 . HIS A 1 105 ? 42.291 77.003 16.991 1.00 24.23 ? 105 HIS A CE1 1 ATOM 643 N NE2 . HIS A 1 105 ? 43.289 77.117 17.854 1.00 22.62 ? 105 HIS A NE2 1 ATOM 644 N N . ASP A 1 106 ? 42.521 70.694 18.989 1.00 15.04 ? 106 ASP A N 1 ATOM 645 C CA . ASP A 1 106 ? 41.903 69.424 19.326 1.00 14.32 ? 106 ASP A CA 1 ATOM 646 C C . ASP A 1 106 ? 42.733 68.154 19.191 1.00 12.73 ? 106 ASP A C 1 ATOM 647 O O . ASP A 1 106 ? 42.868 67.433 20.183 1.00 12.59 ? 106 ASP A O 1 ATOM 648 C CB . ASP A 1 106 ? 40.617 69.204 18.498 1.00 16.32 ? 106 ASP A CB 1 ATOM 649 C CG . ASP A 1 106 ? 39.651 70.348 18.612 1.00 19.35 ? 106 ASP A CG 1 ATOM 650 O OD1 . ASP A 1 106 ? 38.871 70.357 19.576 1.00 20.95 ? 106 ASP A OD1 1 ATOM 651 O OD2 . ASP A 1 106 ? 39.680 71.246 17.740 1.00 20.14 ? 106 ASP A OD2 1 ATOM 652 N N . THR A 1 107 ? 43.243 67.881 17.979 1.00 12.35 ? 107 THR A N 1 ATOM 653 C CA . THR A 1 107 ? 43.904 66.591 17.701 1.00 10.58 ? 107 THR A CA 1 ATOM 654 C C . THR A 1 107 ? 45.160 66.345 18.515 1.00 12.48 ? 107 THR A C 1 ATOM 655 O O . THR A 1 107 ? 45.340 65.235 18.995 1.00 10.90 ? 107 THR A O 1 ATOM 656 C CB . THR A 1 107 ? 44.180 66.446 16.205 1.00 12.48 ? 107 THR A CB 1 ATOM 657 O OG1 . THR A 1 107 ? 42.921 66.635 15.539 1.00 10.57 ? 107 THR A OG1 1 ATOM 658 C CG2 . THR A 1 107 ? 44.812 65.039 15.858 1.00 9.67 ? 107 THR A CG2 1 ATOM 659 N N . LYS A 1 108 ? 46.001 67.361 18.746 1.00 10.88 ? 108 LYS A N 1 ATOM 660 C CA . LYS A 1 108 ? 47.209 67.052 19.550 1.00 11.67 ? 108 LYS A CA 1 ATOM 661 C C . LYS A 1 108 ? 46.791 66.635 20.978 1.00 10.42 ? 108 LYS A C 1 ATOM 662 O O . LYS A 1 108 ? 47.462 65.830 21.606 1.00 11.30 ? 108 LYS A O 1 ATOM 663 C CB . LYS A 1 108 ? 48.198 68.240 19.569 1.00 12.74 ? 108 LYS A CB 1 ATOM 664 C CG . LYS A 1 108 ? 47.881 69.330 20.575 1.00 14.82 ? 108 LYS A CG 1 ATOM 665 C CD . LYS A 1 108 ? 48.966 70.427 20.404 1.00 15.01 ? 108 LYS A CD 1 ATOM 666 C CE . LYS A 1 108 ? 48.775 71.624 21.324 1.00 18.94 ? 108 LYS A CE 1 ATOM 667 N NZ . LYS A 1 108 ? 49.872 72.614 21.197 1.00 18.06 ? 108 LYS A NZ 1 ATOM 668 N N . HIS A 1 109 ? 45.665 67.163 21.461 1.00 12.89 ? 109 HIS A N 1 ATOM 669 C CA . HIS A 1 109 ? 45.167 66.796 22.792 1.00 12.05 ? 109 HIS A CA 1 ATOM 670 C C . HIS A 1 109 ? 44.540 65.386 22.805 1.00 13.12 ? 109 HIS A C 1 ATOM 671 O O . HIS A 1 109 ? 44.721 64.621 23.748 1.00 13.63 ? 109 HIS A O 1 ATOM 672 C CB . HIS A 1 109 ? 44.146 67.826 23.268 1.00 15.14 ? 109 HIS A CB 1 ATOM 673 C CG . HIS A 1 109 ? 44.737 69.177 23.462 1.00 19.23 ? 109 HIS A CG 1 ATOM 674 N ND1 . HIS A 1 109 ? 45.696 69.434 24.432 1.00 22.41 ? 109 HIS A ND1 1 ATOM 675 C CD2 . HIS A 1 109 ? 44.558 70.338 22.789 1.00 21.70 ? 109 HIS A CD2 1 ATOM 676 C CE1 . HIS A 1 109 ? 46.076 70.697 24.334 1.00 21.28 ? 109 HIS A CE1 1 ATOM 677 N NE2 . HIS A 1 109 ? 45.403 71.265 23.355 1.00 20.96 ? 109 HIS A NE2 1 ATOM 678 N N . ILE A 1 110 ? 43.773 65.071 21.759 1.00 11.32 ? 110 ILE A N 1 ATOM 679 C CA . ILE A 1 110 ? 43.174 63.741 21.642 1.00 10.27 ? 110 ILE A CA 1 ATOM 680 C C . ILE A 1 110 ? 44.311 62.679 21.630 1.00 11.14 ? 110 ILE A C 1 ATOM 681 O O . ILE A 1 110 ? 44.255 61.644 22.341 1.00 10.23 ? 110 ILE A O 1 ATOM 682 C CB . ILE A 1 110 ? 42.359 63.641 20.336 1.00 10.28 ? 110 ILE A CB 1 ATOM 683 C CG1 . ILE A 1 110 ? 41.143 64.583 20.384 1.00 12.13 ? 110 ILE A CG1 1 ATOM 684 C CG2 . ILE A 1 110 ? 42.001 62.159 20.065 1.00 8.54 ? 110 ILE A CG2 1 ATOM 685 C CD1 . ILE A 1 110 ? 40.460 64.807 19.018 1.00 8.25 ? 110 ILE A CD1 1 ATOM 686 N N . LEU A 1 111 ? 45.351 62.924 20.839 1.00 10.70 ? 111 LEU A N 1 ATOM 687 C CA . LEU A 1 111 ? 46.418 61.935 20.744 1.00 10.97 ? 111 LEU A CA 1 ATOM 688 C C . LEU A 1 111 ? 47.247 61.846 21.990 1.00 11.20 ? 111 LEU A C 1 ATOM 689 O O . LEU A 1 111 ? 47.708 60.787 22.334 1.00 11.88 ? 111 LEU A O 1 ATOM 690 C CB . LEU A 1 111 ? 47.310 62.235 19.545 1.00 9.65 ? 111 LEU A CB 1 ATOM 691 C CG . LEU A 1 111 ? 46.544 61.855 18.239 1.00 9.30 ? 111 LEU A CG 1 ATOM 692 C CD1 . LEU A 1 111 ? 47.278 62.321 17.023 1.00 11.66 ? 111 LEU A CD1 1 ATOM 693 C CD2 . LEU A 1 111 ? 46.317 60.344 18.198 1.00 12.90 ? 111 LEU A CD2 1 ATOM 694 N N . SER A 1 112 ? 47.467 62.985 22.620 1.00 12.35 ? 112 SER A N 1 ATOM 695 C CA . SER A 1 112 ? 48.245 63.014 23.845 1.00 13.28 ? 112 SER A CA 1 ATOM 696 C C . SER A 1 112 ? 47.510 62.287 24.961 1.00 14.51 ? 112 SER A C 1 ATOM 697 O O . SER A 1 112 ? 48.108 61.484 25.676 1.00 15.31 ? 112 SER A O 1 ATOM 698 C CB . SER A 1 112 ? 48.534 64.468 24.255 1.00 15.44 ? 112 SER A CB 1 ATOM 699 O OG . SER A 1 112 ? 49.326 64.476 25.416 1.00 18.37 ? 112 SER A OG 1 ATOM 700 N N . ASN A 1 113 ? 46.208 62.506 25.053 1.00 13.64 ? 113 ASN A N 1 ATOM 701 C CA . ASN A 1 113 ? 45.475 61.820 26.103 1.00 14.50 ? 113 ASN A CA 1 ATOM 702 C C . ASN A 1 113 ? 45.200 60.352 25.740 1.00 13.78 ? 113 ASN A C 1 ATOM 703 O O . ASN A 1 113 ? 45.096 59.525 26.658 1.00 14.59 ? 113 ASN A O 1 ATOM 704 C CB . ASN A 1 113 ? 44.221 62.604 26.460 1.00 14.82 ? 113 ASN A CB 1 ATOM 705 C CG . ASN A 1 113 ? 44.578 63.938 27.117 1.00 17.30 ? 113 ASN A CG 1 ATOM 706 O OD1 . ASN A 1 113 ? 45.642 64.042 27.801 1.00 22.02 ? 113 ASN A OD1 1 ATOM 707 N ND2 . ASN A 1 113 ? 43.758 64.940 26.934 1.00 16.83 ? 113 ASN A ND2 1 ATOM 708 N N . ALA A 1 114 ? 45.156 60.001 24.437 1.00 13.12 ? 114 ALA A N 1 ATOM 709 C CA . ALA A 1 114 ? 45.008 58.582 24.056 1.00 11.60 ? 114 ALA A CA 1 ATOM 710 C C . ALA A 1 114 ? 46.297 57.884 24.516 1.00 13.10 ? 114 ALA A C 1 ATOM 711 O O . ALA A 1 114 ? 46.231 56.808 25.106 1.00 11.50 ? 114 ALA A O 1 ATOM 712 C CB . ALA A 1 114 ? 44.831 58.427 22.522 1.00 9.73 ? 114 ALA A CB 1 ATOM 713 N N . LEU A 1 115 ? 47.474 58.464 24.250 1.00 11.87 ? 115 LEU A N 1 ATOM 714 C CA . LEU A 1 115 ? 48.703 57.791 24.703 1.00 13.04 ? 115 LEU A CA 1 ATOM 715 C C . LEU A 1 115 ? 48.689 57.561 26.232 1.00 12.41 ? 115 LEU A C 1 ATOM 716 O O . LEU A 1 115 ? 48.983 56.466 26.707 1.00 14.63 ? 115 LEU A O 1 ATOM 717 C CB . LEU A 1 115 ? 49.966 58.583 24.256 1.00 13.20 ? 115 LEU A CB 1 ATOM 718 C CG . LEU A 1 115 ? 51.346 58.093 24.709 1.00 11.51 ? 115 LEU A CG 1 ATOM 719 C CD1 . LEU A 1 115 ? 51.572 56.630 24.379 1.00 13.34 ? 115 LEU A CD1 1 ATOM 720 C CD2 . LEU A 1 115 ? 52.420 58.961 24.084 1.00 12.43 ? 115 LEU A CD2 1 ATOM 721 N N . ARG A 1 116 ? 48.275 58.582 26.999 1.00 13.78 ? 116 ARG A N 1 ATOM 722 C CA . ARG A 1 116 ? 48.264 58.471 28.459 1.00 13.73 ? 116 ARG A CA 1 ATOM 723 C C . ARG A 1 116 ? 47.265 57.442 28.950 1.00 13.15 ? 116 ARG A C 1 ATOM 724 O O . ARG A 1 116 ? 47.615 56.557 29.732 1.00 12.88 ? 116 ARG A O 1 ATOM 725 C CB . ARG A 1 116 ? 47.933 59.815 29.095 1.00 16.70 ? 116 ARG A CB 1 ATOM 726 C CG . ARG A 1 116 ? 47.831 59.760 30.632 1.00 21.69 ? 116 ARG A CG 1 ATOM 727 C CD . ARG A 1 116 ? 46.422 59.370 31.119 1.00 26.79 ? 116 ARG A CD 1 ATOM 728 N NE . ARG A 1 116 ? 46.111 59.906 32.462 1.00 33.87 ? 116 ARG A NE 1 ATOM 729 C CZ . ARG A 1 116 ? 46.018 61.209 32.747 1.00 34.77 ? 116 ARG A CZ 1 ATOM 730 N NH1 . ARG A 1 116 ? 46.208 62.112 31.780 1.00 37.43 ? 116 ARG A NH1 1 ATOM 731 N NH2 . ARG A 1 116 ? 45.744 61.622 33.995 1.00 36.69 ? 116 ARG A NH2 1 ATOM 732 N N . HIS A 1 117 ? 46.039 57.522 28.442 1.00 12.28 ? 117 HIS A N 1 ATOM 733 C CA . HIS A 1 117 ? 45.013 56.605 28.890 1.00 13.10 ? 117 HIS A CA 1 ATOM 734 C C . HIS A 1 117 ? 45.197 55.176 28.448 1.00 12.74 ? 117 HIS A C 1 ATOM 735 O O . HIS A 1 117 ? 44.895 54.273 29.185 1.00 11.28 ? 117 HIS A O 1 ATOM 736 C CB . HIS A 1 117 ? 43.640 57.161 28.516 1.00 13.60 ? 117 HIS A CB 1 ATOM 737 C CG A HIS A 1 117 ? 43.236 58.316 29.376 0.50 15.18 ? 117 HIS A CG 1 ATOM 738 C CG B HIS A 1 117 ? 42.786 57.532 29.526 0.50 19.85 ? 117 HIS A CG 1 ATOM 739 N ND1 A HIS A 1 117 ? 42.527 58.153 30.551 0.50 15.29 ? 117 HIS A ND1 1 ATOM 740 N ND1 B HIS A 1 117 ? 42.036 56.675 30.299 0.50 21.89 ? 117 HIS A ND1 1 ATOM 741 C CD2 A HIS A 1 117 ? 43.574 59.627 29.320 0.50 16.07 ? 117 HIS A CD2 1 ATOM 742 C CD2 B HIS A 1 117 ? 42.590 58.768 30.034 0.50 21.10 ? 117 HIS A CD2 1 ATOM 743 C CE1 A HIS A 1 117 ? 42.455 59.315 31.182 0.50 16.58 ? 117 HIS A CE1 1 ATOM 744 C CE1 B HIS A 1 117 ? 41.412 57.364 31.235 0.50 20.33 ? 117 HIS A CE1 1 ATOM 745 N NE2 A HIS A 1 117 ? 43.083 60.223 30.459 0.50 15.58 ? 117 HIS A NE2 1 ATOM 746 N NE2 B HIS A 1 117 ? 41.734 58.638 31.097 0.50 21.92 ? 117 HIS A NE2 1 ATOM 747 N N . LEU A 1 118 ? 45.685 54.945 27.238 1.00 10.76 ? 118 LEU A N 1 ATOM 748 C CA . LEU A 1 118 ? 45.916 53.567 26.840 1.00 12.21 ? 118 LEU A CA 1 ATOM 749 C C . LEU A 1 118 ? 47.149 53.047 27.592 1.00 12.74 ? 118 LEU A C 1 ATOM 750 O O . LEU A 1 118 ? 47.170 51.934 28.065 1.00 12.64 ? 118 LEU A O 1 ATOM 751 C CB . LEU A 1 118 ? 46.118 53.506 25.327 1.00 11.08 ? 118 LEU A CB 1 ATOM 752 C CG . LEU A 1 118 ? 44.844 53.931 24.531 1.00 12.61 ? 118 LEU A CG 1 ATOM 753 C CD1 . LEU A 1 118 ? 45.304 53.844 23.018 1.00 14.08 ? 118 LEU A CD1 1 ATOM 754 C CD2 . LEU A 1 118 ? 43.604 53.145 24.756 1.00 13.78 ? 118 LEU A CD2 1 ATOM 755 N N . HIS A 1 119 ? 48.179 53.872 27.758 1.00 13.18 ? 119 HIS A N 1 ATOM 756 C CA . HIS A 1 119 ? 49.349 53.421 28.511 1.00 14.30 ? 119 HIS A CA 1 ATOM 757 C C . HIS A 1 119 ? 48.899 52.960 29.921 1.00 15.08 ? 119 HIS A C 1 ATOM 758 O O . HIS A 1 119 ? 49.225 51.870 30.369 1.00 16.40 ? 119 HIS A O 1 ATOM 759 C CB . HIS A 1 119 ? 50.323 54.590 28.668 1.00 15.88 ? 119 HIS A CB 1 ATOM 760 C CG . HIS A 1 119 ? 51.525 54.267 29.501 1.00 17.71 ? 119 HIS A CG 1 ATOM 761 N ND1 . HIS A 1 119 ? 51.594 54.581 30.842 1.00 18.61 ? 119 HIS A ND1 1 ATOM 762 C CD2 . HIS A 1 119 ? 52.666 53.609 29.206 1.00 18.12 ? 119 HIS A CD2 1 ATOM 763 C CE1 . HIS A 1 119 ? 52.740 54.132 31.334 1.00 19.34 ? 119 HIS A CE1 1 ATOM 764 N NE2 . HIS A 1 119 ? 53.407 53.538 30.365 1.00 19.28 ? 119 HIS A NE2 1 ATOM 765 N N . ASP A 1 120 ? 48.092 53.792 30.585 1.00 15.71 ? 120 ASP A N 1 ATOM 766 C CA . ASP A 1 120 ? 47.628 53.493 31.962 1.00 16.41 ? 120 ASP A CA 1 ATOM 767 C C . ASP A 1 120 ? 46.483 52.488 32.177 1.00 16.99 ? 120 ASP A C 1 ATOM 768 O O . ASP A 1 120 ? 46.258 52.040 33.310 1.00 17.30 ? 120 ASP A O 1 ATOM 769 C CB . ASP A 1 120 ? 47.236 54.796 32.660 1.00 17.39 ? 120 ASP A CB 1 ATOM 770 C CG . ASP A 1 120 ? 48.420 55.751 32.855 1.00 19.99 ? 120 ASP A CG 1 ATOM 771 O OD1 . ASP A 1 120 ? 49.612 55.337 32.760 1.00 19.87 ? 120 ASP A OD1 1 ATOM 772 O OD2 . ASP A 1 120 ? 48.136 56.937 33.134 1.00 20.13 ? 120 ASP A OD2 1 ATOM 773 N N . ASN A 1 121 ? 45.728 52.165 31.122 1.00 14.03 ? 121 ASN A N 1 ATOM 774 C CA . ASN A 1 121 ? 44.600 51.241 31.195 1.00 14.38 ? 121 ASN A CA 1 ATOM 775 C C . ASN A 1 121 ? 44.741 50.185 30.090 1.00 14.13 ? 121 ASN A C 1 ATOM 776 O O . ASN A 1 121 ? 44.161 50.314 29.037 1.00 13.97 ? 121 ASN A O 1 ATOM 777 C CB . ASN A 1 121 ? 43.288 52.016 31.005 1.00 11.56 ? 121 ASN A CB 1 ATOM 778 C CG . ASN A 1 121 ? 43.078 53.027 32.121 1.00 15.53 ? 121 ASN A CG 1 ATOM 779 O OD1 . ASN A 1 121 ? 42.577 52.665 33.216 1.00 14.68 ? 121 ASN A OD1 1 ATOM 780 N ND2 . ASN A 1 121 ? 43.453 54.278 31.868 1.00 13.93 ? 121 ASN A ND2 1 ATOM 781 N N . PRO A 1 122 ? 45.496 49.107 30.343 1.00 14.44 ? 122 PRO A N 1 ATOM 782 C CA . PRO A 1 122 ? 45.793 48.001 29.407 1.00 14.91 ? 122 PRO A CA 1 ATOM 783 C C . PRO A 1 122 ? 44.666 47.409 28.612 1.00 13.65 ? 122 PRO A C 1 ATOM 784 O O . PRO A 1 122 ? 44.893 46.945 27.487 1.00 14.53 ? 122 PRO A O 1 ATOM 785 C CB . PRO A 1 122 ? 46.509 46.961 30.295 1.00 16.17 ? 122 PRO A CB 1 ATOM 786 C CG . PRO A 1 122 ? 46.251 47.389 31.653 1.00 17.94 ? 122 PRO A CG 1 ATOM 787 C CD . PRO A 1 122 ? 46.047 48.847 31.685 1.00 15.85 ? 122 PRO A CD 1 ATOM 788 N N . GLU A 1 123 ? 43.462 47.405 29.187 1.00 13.32 ? 123 GLU A N 1 ATOM 789 C CA . GLU A 1 123 ? 42.285 46.857 28.512 1.00 13.03 ? 123 GLU A CA 1 ATOM 790 C C . GLU A 1 123 ? 41.579 47.785 27.525 1.00 12.18 ? 123 GLU A C 1 ATOM 791 O O . GLU A 1 123 ? 40.726 47.318 26.743 1.00 13.51 ? 123 GLU A O 1 ATOM 792 C CB . GLU A 1 123 ? 41.223 46.440 29.566 1.00 15.97 ? 123 GLU A CB 1 ATOM 793 C CG . GLU A 1 123 ? 40.372 47.647 30.137 1.00 19.35 ? 123 GLU A CG 1 ATOM 794 C CD . GLU A 1 123 ? 41.096 48.600 31.119 1.00 19.60 ? 123 GLU A CD 1 ATOM 795 O OE1 . GLU A 1 123 ? 42.323 48.523 31.319 1.00 17.05 ? 123 GLU A OE1 1 ATOM 796 O OE2 . GLU A 1 123 ? 40.398 49.458 31.741 1.00 24.29 ? 123 GLU A OE2 1 ATOM 797 N N . MET A 1 124 ? 41.881 49.090 27.603 1.00 11.69 ? 124 MET A N 1 ATOM 798 C CA . MET A 1 124 ? 41.220 50.080 26.748 1.00 12.38 ? 124 MET A CA 1 ATOM 799 C C . MET A 1 124 ? 41.838 49.924 25.363 1.00 10.81 ? 124 MET A C 1 ATOM 800 O O . MET A 1 124 ? 43.022 49.630 25.254 1.00 10.99 ? 124 MET A O 1 ATOM 801 C CB . MET A 1 124 ? 41.510 51.490 27.283 1.00 11.77 ? 124 MET A CB 1 ATOM 802 C CG . MET A 1 124 ? 40.686 52.638 26.568 1.00 12.34 ? 124 MET A CG 1 ATOM 803 S SD . MET A 1 124 ? 38.931 52.248 26.538 1.00 13.62 ? 124 MET A SD 1 ATOM 804 C CE . MET A 1 124 ? 38.241 53.730 25.884 1.00 12.82 ? 124 MET A CE 1 ATOM 805 N N . LYS A 1 125 ? 41.044 50.213 24.345 1.00 11.86 ? 125 LYS A N 1 ATOM 806 C CA . LYS A 1 125 ? 41.396 50.155 22.914 1.00 10.24 ? 125 LYS A CA 1 ATOM 807 C C . LYS A 1 125 ? 41.010 51.455 22.199 1.00 9.23 ? 125 LYS A C 1 ATOM 808 O O . LYS A 1 125 ? 40.144 52.177 22.653 1.00 8.99 ? 125 LYS A O 1 ATOM 809 C CB . LYS A 1 125 ? 40.640 48.958 22.287 1.00 12.82 ? 125 LYS A CB 1 ATOM 810 C CG . LYS A 1 125 ? 40.936 47.569 22.806 1.00 16.63 ? 125 LYS A CG 1 ATOM 811 C CD . LYS A 1 125 ? 42.395 47.194 22.675 1.00 18.47 ? 125 LYS A CD 1 ATOM 812 C CE . LYS A 1 125 ? 42.751 45.795 23.166 1.00 22.94 ? 125 LYS A CE 1 ATOM 813 N NZ . LYS A 1 125 ? 41.647 44.891 22.881 1.00 25.04 ? 125 LYS A NZ 1 ATOM 814 N N . PHE A 1 126 ? 41.623 51.721 21.032 1.00 9.34 ? 126 PHE A N 1 ATOM 815 C CA . PHE A 1 126 ? 41.310 52.898 20.276 1.00 9.39 ? 126 PHE A CA 1 ATOM 816 C C . PHE A 1 126 ? 41.813 52.644 18.848 1.00 8.49 ? 126 PHE A C 1 ATOM 817 O O . PHE A 1 126 ? 42.867 52.030 18.672 1.00 9.78 ? 126 PHE A O 1 ATOM 818 C CB . PHE A 1 126 ? 42.065 54.099 20.917 1.00 8.08 ? 126 PHE A CB 1 ATOM 819 C CG . PHE A 1 126 ? 41.702 55.469 20.411 1.00 10.04 ? 126 PHE A CG 1 ATOM 820 C CD1 . PHE A 1 126 ? 40.361 55.903 20.364 1.00 9.59 ? 126 PHE A CD1 1 ATOM 821 C CD2 . PHE A 1 126 ? 42.749 56.420 20.091 1.00 8.79 ? 126 PHE A CD2 1 ATOM 822 C CE1 . PHE A 1 126 ? 40.063 57.215 20.012 1.00 9.81 ? 126 PHE A CE1 1 ATOM 823 C CE2 . PHE A 1 126 ? 42.452 57.741 19.750 1.00 8.25 ? 126 PHE A CE2 1 ATOM 824 C CZ . PHE A 1 126 ? 41.120 58.138 19.702 1.00 6.31 ? 126 PHE A CZ 1 ATOM 825 N N . ILE A 1 127 ? 41.061 53.117 17.850 1.00 6.85 ? 127 ILE A N 1 ATOM 826 C CA . ILE A 1 127 ? 41.476 53.034 16.443 1.00 6.59 ? 127 ILE A CA 1 ATOM 827 C C . ILE A 1 127 ? 41.765 54.452 15.948 1.00 7.08 ? 127 ILE A C 1 ATOM 828 O O . ILE A 1 127 ? 41.108 55.421 16.328 1.00 8.03 ? 127 ILE A O 1 ATOM 829 C CB . ILE A 1 127 ? 40.452 52.290 15.527 1.00 7.08 ? 127 ILE A CB 1 ATOM 830 C CG1 . ILE A 1 127 ? 39.052 52.872 15.502 1.00 6.70 ? 127 ILE A CG1 1 ATOM 831 C CG2 . ILE A 1 127 ? 40.389 50.804 15.960 1.00 8.18 ? 127 ILE A CG2 1 ATOM 832 C CD1 . ILE A 1 127 ? 38.124 52.285 14.412 1.00 6.03 ? 127 ILE A CD1 1 ATOM 833 N N . TRP A 1 128 ? 42.670 54.550 15.000 1.00 7.31 ? 128 TRP A N 1 ATOM 834 C CA . TRP A 1 128 ? 43.098 55.820 14.427 1.00 7.15 ? 128 TRP A CA 1 ATOM 835 C C . TRP A 1 128 ? 43.204 55.704 12.899 1.00 7.68 ? 128 TRP A C 1 ATOM 836 O O . TRP A 1 128 ? 43.833 54.733 12.420 1.00 7.42 ? 128 TRP A O 1 ATOM 837 C CB . TRP A 1 128 ? 44.439 56.221 14.987 1.00 8.07 ? 128 TRP A CB 1 ATOM 838 C CG . TRP A 1 128 ? 44.693 57.666 14.651 1.00 8.69 ? 128 TRP A CG 1 ATOM 839 C CD1 . TRP A 1 128 ? 45.416 58.167 13.558 1.00 5.67 ? 128 TRP A CD1 1 ATOM 840 C CD2 . TRP A 1 128 ? 44.130 58.791 15.302 1.00 7.38 ? 128 TRP A CD2 1 ATOM 841 N NE1 . TRP A 1 128 ? 45.321 59.551 13.527 1.00 7.27 ? 128 TRP A NE1 1 ATOM 842 C CE2 . TRP A 1 128 ? 44.543 59.964 14.578 1.00 5.02 ? 128 TRP A CE2 1 ATOM 843 C CE3 . TRP A 1 128 ? 43.296 58.939 16.414 1.00 8.07 ? 128 TRP A CE3 1 ATOM 844 C CZ2 . TRP A 1 128 ? 44.160 61.240 14.962 1.00 6.59 ? 128 TRP A CZ2 1 ATOM 845 C CZ3 . TRP A 1 128 ? 42.910 60.207 16.783 1.00 9.26 ? 128 TRP A CZ3 1 ATOM 846 C CH2 . TRP A 1 128 ? 43.351 61.358 16.064 1.00 8.58 ? 128 TRP A CH2 1 ATOM 847 N N . ALA A 1 129 ? 42.642 56.674 12.155 1.00 7.48 ? 129 ALA A N 1 ATOM 848 C CA . ALA A 1 129 ? 42.636 56.607 10.718 1.00 8.36 ? 129 ALA A CA 1 ATOM 849 C C . ALA A 1 129 ? 43.534 57.590 9.995 1.00 8.29 ? 129 ALA A C 1 ATOM 850 O O . ALA A 1 129 ? 44.114 57.204 8.994 1.00 8.46 ? 129 ALA A O 1 ATOM 851 C CB . ALA A 1 129 ? 41.166 56.824 10.192 1.00 6.89 ? 129 ALA A CB 1 ATOM 852 N N . GLU A 1 130 ? 43.602 58.842 10.437 1.00 9.57 ? 130 GLU A N 1 ATOM 853 C CA . GLU A 1 130 ? 44.269 59.910 9.645 1.00 7.90 ? 130 GLU A CA 1 ATOM 854 C C . GLU A 1 130 ? 45.739 60.032 10.004 1.00 7.91 ? 130 GLU A C 1 ATOM 855 O O . GLU A 1 130 ? 46.116 60.634 11.053 1.00 9.47 ? 130 GLU A O 1 ATOM 856 C CB . GLU A 1 130 ? 43.502 61.234 9.851 1.00 7.97 ? 130 GLU A CB 1 ATOM 857 C CG . GLU A 1 130 ? 41.950 61.125 9.566 1.00 9.11 ? 130 GLU A CG 1 ATOM 858 C CD . GLU A 1 130 ? 41.103 60.644 10.769 1.00 10.32 ? 130 GLU A CD 1 ATOM 859 O OE1 . GLU A 1 130 ? 41.622 60.440 11.882 1.00 9.89 ? 130 GLU A OE1 1 ATOM 860 O OE2 . GLU A 1 130 ? 39.838 60.552 10.592 1.00 12.81 ? 130 GLU A OE2 1 ATOM 861 N N . ILE A 1 131 ? 46.590 59.517 9.103 1.00 6.72 ? 131 ILE A N 1 ATOM 862 C CA . ILE A 1 131 ? 48.008 59.491 9.425 1.00 8.00 ? 131 ILE A CA 1 ATOM 863 C C . ILE A 1 131 ? 48.623 60.914 9.298 1.00 9.07 ? 131 ILE A C 1 ATOM 864 O O . ILE A 1 131 ? 49.604 61.198 9.953 1.00 9.72 ? 131 ILE A O 1 ATOM 865 C CB . ILE A 1 131 ? 48.749 58.427 8.577 1.00 7.68 ? 131 ILE A CB 1 ATOM 866 C CG1 . ILE A 1 131 ? 48.113 57.028 8.892 1.00 7.83 ? 131 ILE A CG1 1 ATOM 867 C CG2 . ILE A 1 131 ? 50.247 58.455 8.914 1.00 8.20 ? 131 ILE A CG2 1 ATOM 868 C CD1 . ILE A 1 131 ? 47.925 56.779 10.450 1.00 11.74 ? 131 ILE A CD1 1 ATOM 869 N N . SER A 1 132 ? 48.058 61.829 8.493 1.00 7.45 ? 132 SER A N 1 ATOM 870 C CA . SER A 1 132 ? 48.587 63.228 8.413 1.00 8.03 ? 132 SER A CA 1 ATOM 871 C C . SER A 1 132 ? 48.690 63.796 9.830 1.00 6.95 ? 132 SER A C 1 ATOM 872 O O . SER A 1 132 ? 49.731 64.321 10.197 1.00 9.90 ? 132 SER A O 1 ATOM 873 C CB . SER A 1 132 ? 47.636 64.044 7.538 1.00 7.02 ? 132 SER A CB 1 ATOM 874 O OG . SER A 1 132 ? 46.284 64.011 7.918 1.00 7.92 ? 132 SER A OG 1 ATOM 875 N N . TYR A 1 133 ? 47.613 63.690 10.616 1.00 8.38 ? 133 TYR A N 1 ATOM 876 C CA . TYR A 1 133 ? 47.596 64.120 12.004 1.00 8.58 ? 133 TYR A CA 1 ATOM 877 C C . TYR A 1 133 ? 48.553 63.308 12.891 1.00 9.85 ? 133 TYR A C 1 ATOM 878 O O . TYR A 1 133 ? 49.230 63.888 13.764 1.00 11.51 ? 133 TYR A O 1 ATOM 879 C CB . TYR A 1 133 ? 46.203 64.014 12.583 1.00 10.56 ? 133 TYR A CB 1 ATOM 880 C CG . TYR A 1 133 ? 45.334 65.159 12.274 1.00 9.01 ? 133 TYR A CG 1 ATOM 881 C CD1 . TYR A 1 133 ? 45.737 66.457 12.554 1.00 11.79 ? 133 TYR A CD1 1 ATOM 882 C CD2 . TYR A 1 133 ? 44.092 64.968 11.721 1.00 9.16 ? 133 TYR A CD2 1 ATOM 883 C CE1 . TYR A 1 133 ? 44.884 67.539 12.283 1.00 11.08 ? 133 TYR A CE1 1 ATOM 884 C CE2 . TYR A 1 133 ? 43.253 66.027 11.469 1.00 10.36 ? 133 TYR A CE2 1 ATOM 885 C CZ . TYR A 1 133 ? 43.655 67.316 11.746 1.00 10.73 ? 133 TYR A CZ 1 ATOM 886 O OH . TYR A 1 133 ? 42.790 68.364 11.481 1.00 10.85 ? 133 TYR A OH 1 ATOM 887 N N . PHE A 1 134 ? 48.612 61.989 12.696 1.00 8.85 ? 134 PHE A N 1 ATOM 888 C CA . PHE A 1 134 ? 49.473 61.184 13.564 1.00 10.03 ? 134 PHE A CA 1 ATOM 889 C C . PHE A 1 134 ? 50.951 61.499 13.364 1.00 10.07 ? 134 PHE A C 1 ATOM 890 O O . PHE A 1 134 ? 51.709 61.556 14.354 1.00 11.34 ? 134 PHE A O 1 ATOM 891 C CB . PHE A 1 134 ? 49.193 59.699 13.390 1.00 9.92 ? 134 PHE A CB 1 ATOM 892 C CG . PHE A 1 134 ? 49.734 58.868 14.525 1.00 11.49 ? 134 PHE A CG 1 ATOM 893 C CD1 . PHE A 1 134 ? 48.938 58.632 15.673 1.00 13.05 ? 134 PHE A CD1 1 ATOM 894 C CD2 . PHE A 1 134 ? 51.024 58.336 14.454 1.00 11.82 ? 134 PHE A CD2 1 ATOM 895 C CE1 . PHE A 1 134 ? 49.434 57.887 16.704 1.00 12.17 ? 134 PHE A CE1 1 ATOM 896 C CE2 . PHE A 1 134 ? 51.531 57.589 15.494 1.00 12.38 ? 134 PHE A CE2 1 ATOM 897 C CZ . PHE A 1 134 ? 50.741 57.365 16.618 1.00 10.61 ? 134 PHE A CZ 1 ATOM 898 N N . ALA A 1 135 ? 51.354 61.631 12.100 1.00 12.03 ? 135 ALA A N 1 ATOM 899 C CA . ALA A 1 135 ? 52.735 61.983 11.763 1.00 12.19 ? 135 ALA A CA 1 ATOM 900 C C . ALA A 1 135 ? 53.024 63.368 12.370 1.00 13.09 ? 135 ALA A C 1 ATOM 901 O O . ALA A 1 135 ? 54.105 63.549 12.965 1.00 15.21 ? 135 ALA A O 1 ATOM 902 C CB . ALA A 1 135 ? 52.951 61.997 10.239 1.00 12.09 ? 135 ALA A CB 1 ATOM 903 N N . ARG A 1 136 ? 52.100 64.314 12.243 1.00 11.76 ? 136 ARG A N 1 ATOM 904 C CA . ARG A 1 136 ? 52.270 65.687 12.759 1.00 13.92 ? 136 ARG A CA 1 ATOM 905 C C . ARG A 1 136 ? 52.510 65.610 14.272 1.00 13.89 ? 136 ARG A C 1 ATOM 906 O O . ARG A 1 136 ? 53.359 66.307 14.827 1.00 18.36 ? 136 ARG A O 1 ATOM 907 C CB . ARG A 1 136 ? 51.033 66.546 12.456 1.00 14.75 ? 136 ARG A CB 1 ATOM 908 C CG . ARG A 1 136 ? 50.954 67.882 13.248 1.00 16.35 ? 136 ARG A CG 1 ATOM 909 C CD . ARG A 1 136 ? 51.876 68.942 12.563 1.00 19.48 ? 136 ARG A CD 1 ATOM 910 N NE . ARG A 1 136 ? 51.799 70.255 13.205 1.00 17.73 ? 136 ARG A NE 1 ATOM 911 C CZ . ARG A 1 136 ? 52.562 70.592 14.238 1.00 19.33 ? 136 ARG A CZ 1 ATOM 912 N NH1 . ARG A 1 136 ? 53.439 69.710 14.708 1.00 20.56 ? 136 ARG A NH1 1 ATOM 913 N NH2 . ARG A 1 136 ? 52.455 71.785 14.791 1.00 15.93 ? 136 ARG A NH2 1 ATOM 914 N N . PHE A 1 137 ? 51.794 64.728 14.953 1.00 14.45 ? 137 PHE A N 1 ATOM 915 C CA . PHE A 1 137 ? 51.904 64.565 16.392 1.00 13.13 ? 137 PHE A CA 1 ATOM 916 C C . PHE A 1 137 ? 53.182 63.843 16.824 1.00 14.63 ? 137 PHE A C 1 ATOM 917 O O . PHE A 1 137 ? 53.968 64.323 17.685 1.00 16.19 ? 137 PHE A O 1 ATOM 918 C CB . PHE A 1 137 ? 50.685 63.762 16.847 1.00 12.00 ? 137 PHE A CB 1 ATOM 919 C CG . PHE A 1 137 ? 50.666 63.474 18.314 1.00 11.43 ? 137 PHE A CG 1 ATOM 920 C CD1 . PHE A 1 137 ? 50.331 64.454 19.249 1.00 12.69 ? 137 PHE A CD1 1 ATOM 921 C CD2 . PHE A 1 137 ? 51.033 62.205 18.773 1.00 12.81 ? 137 PHE A CD2 1 ATOM 922 C CE1 . PHE A 1 137 ? 50.367 64.169 20.645 1.00 13.84 ? 137 PHE A CE1 1 ATOM 923 C CE2 . PHE A 1 137 ? 51.077 61.951 20.179 1.00 13.74 ? 137 PHE A CE2 1 ATOM 924 C CZ . PHE A 1 137 ? 50.739 62.954 21.090 1.00 13.30 ? 137 PHE A CZ 1 ATOM 925 N N . TYR A 1 138 ? 53.421 62.695 16.203 1.00 16.50 ? 138 TYR A N 1 ATOM 926 C CA . TYR A 1 138 ? 54.539 61.859 16.574 1.00 18.98 ? 138 TYR A CA 1 ATOM 927 C C . TYR A 1 138 ? 55.899 62.524 16.391 1.00 19.96 ? 138 TYR A C 1 ATOM 928 O O . TYR A 1 138 ? 56.841 62.277 17.181 1.00 21.45 ? 138 TYR A O 1 ATOM 929 C CB . TYR A 1 138 ? 54.481 60.548 15.792 1.00 16.80 ? 138 TYR A CB 1 ATOM 930 C CG . TYR A 1 138 ? 55.540 59.550 16.161 1.00 18.12 ? 138 TYR A CG 1 ATOM 931 C CD1 . TYR A 1 138 ? 56.756 59.526 15.488 1.00 17.77 ? 138 TYR A CD1 1 ATOM 932 C CD2 . TYR A 1 138 ? 55.286 58.577 17.129 1.00 18.37 ? 138 TYR A CD2 1 ATOM 933 C CE1 . TYR A 1 138 ? 57.724 58.529 15.762 1.00 17.48 ? 138 TYR A CE1 1 ATOM 934 C CE2 . TYR A 1 138 ? 56.228 57.589 17.415 1.00 19.54 ? 138 TYR A CE2 1 ATOM 935 C CZ . TYR A 1 138 ? 57.440 57.572 16.730 1.00 17.99 ? 138 TYR A CZ 1 ATOM 936 O OH . TYR A 1 138 ? 58.347 56.572 17.044 1.00 20.64 ? 138 TYR A OH 1 ATOM 937 N N . HIS A 1 139 ? 56.043 63.357 15.383 1.00 22.45 ? 139 HIS A N 1 ATOM 938 C CA . HIS A 1 139 ? 57.353 63.957 15.213 1.00 24.06 ? 139 HIS A CA 1 ATOM 939 C C . HIS A 1 139 ? 57.613 65.006 16.262 1.00 24.45 ? 139 HIS A C 1 ATOM 940 O O . HIS A 1 139 ? 58.754 65.426 16.444 1.00 25.86 ? 139 HIS A O 1 ATOM 941 C CB . HIS A 1 139 ? 57.514 64.500 13.799 1.00 25.57 ? 139 HIS A CB 1 ATOM 942 C CG . HIS A 1 139 ? 57.682 63.419 12.776 1.00 28.37 ? 139 HIS A CG 1 ATOM 943 N ND1 . HIS A 1 139 ? 58.822 62.638 12.698 1.00 28.34 ? 139 HIS A ND1 1 ATOM 944 C CD2 . HIS A 1 139 ? 56.836 62.955 11.818 1.00 27.47 ? 139 HIS A CD2 1 ATOM 945 C CE1 . HIS A 1 139 ? 58.672 61.746 11.734 1.00 30.03 ? 139 HIS A CE1 1 ATOM 946 N NE2 . HIS A 1 139 ? 57.481 61.919 11.182 1.00 30.09 ? 139 HIS A NE2 1 ATOM 947 N N . ASP A 1 140 ? 56.561 65.449 16.943 1.00 22.54 ? 140 ASP A N 1 ATOM 948 C CA . ASP A 1 140 ? 56.707 66.419 18.012 1.00 23.74 ? 140 ASP A CA 1 ATOM 949 C C . ASP A 1 140 ? 56.924 65.752 19.387 1.00 21.88 ? 140 ASP A C 1 ATOM 950 O O . ASP A 1 140 ? 57.172 66.430 20.383 1.00 21.16 ? 140 ASP A O 1 ATOM 951 C CB . ASP A 1 140 ? 55.513 67.369 18.049 1.00 24.34 ? 140 ASP A CB 1 ATOM 952 C CG . ASP A 1 140 ? 55.633 68.471 16.998 1.00 28.63 ? 140 ASP A CG 1 ATOM 953 O OD1 . ASP A 1 140 ? 56.163 68.196 15.895 1.00 29.48 ? 140 ASP A OD1 1 ATOM 954 O OD2 . ASP A 1 140 ? 55.210 69.599 17.254 1.00 27.99 ? 140 ASP A OD2 1 ATOM 955 N N . LEU A 1 141 ? 56.847 64.423 19.432 1.00 20.29 ? 141 LEU A N 1 ATOM 956 C CA . LEU A 1 141 ? 57.080 63.723 20.704 1.00 19.98 ? 141 LEU A CA 1 ATOM 957 C C . LEU A 1 141 ? 58.558 63.498 21.026 1.00 20.22 ? 141 LEU A C 1 ATOM 958 O O . LEU A 1 141 ? 59.413 63.272 20.139 1.00 20.10 ? 141 LEU A O 1 ATOM 959 C CB . LEU A 1 141 ? 56.447 62.328 20.745 1.00 20.35 ? 141 LEU A CB 1 ATOM 960 C CG . LEU A 1 141 ? 54.927 62.081 20.776 1.00 19.45 ? 141 LEU A CG 1 ATOM 961 C CD1 . LEU A 1 141 ? 54.726 60.553 20.607 1.00 16.46 ? 141 LEU A CD1 1 ATOM 962 C CD2 . LEU A 1 141 ? 54.280 62.602 22.073 1.00 20.10 ? 141 LEU A CD2 1 ATOM 963 N N . GLY A 1 142 ? 58.807 63.498 22.335 1.00 20.59 ? 142 GLY A N 1 ATOM 964 C CA . GLY A 1 142 ? 60.146 63.214 22.840 1.00 21.28 ? 142 GLY A CA 1 ATOM 965 C C . GLY A 1 142 ? 60.327 61.720 22.714 1.00 22.01 ? 142 GLY A C 1 ATOM 966 O O . GLY A 1 142 ? 59.340 60.977 22.638 1.00 22.35 ? 142 GLY A O 1 ATOM 967 N N . GLU A 1 143 ? 61.575 61.266 22.717 1.00 22.63 ? 143 GLU A N 1 ATOM 968 C CA . GLU A 1 143 ? 61.889 59.864 22.558 1.00 23.37 ? 143 GLU A CA 1 ATOM 969 C C . GLU A 1 143 ? 61.182 58.979 23.563 1.00 23.31 ? 143 GLU A C 1 ATOM 970 O O . GLU A 1 143 ? 60.765 57.855 23.218 1.00 22.32 ? 143 GLU A O 1 ATOM 971 C CB . GLU A 1 143 ? 63.397 59.629 22.655 1.00 25.13 ? 143 GLU A CB 1 ATOM 972 C CG . GLU A 1 143 ? 63.906 58.291 22.061 1.00 29.55 ? 143 GLU A CG 1 ATOM 973 C CD . GLU A 1 143 ? 63.466 58.026 20.606 1.00 32.04 ? 143 GLU A CD 1 ATOM 974 O OE1 . GLU A 1 143 ? 63.611 58.924 19.733 1.00 33.93 ? 143 GLU A OE1 1 ATOM 975 O OE2 . GLU A 1 143 ? 62.993 56.892 20.333 1.00 35.28 ? 143 GLU A OE2 1 ATOM 976 N N . ASN A 1 144 ? 61.007 59.453 24.788 1.00 22.67 ? 144 ASN A N 1 ATOM 977 C CA . ASN A 1 144 ? 60.346 58.578 25.736 1.00 23.09 ? 144 ASN A CA 1 ATOM 978 C C . ASN A 1 144 ? 58.878 58.296 25.319 1.00 21.51 ? 144 ASN A C 1 ATOM 979 O O . ASN A 1 144 ? 58.431 57.155 25.366 1.00 21.16 ? 144 ASN A O 1 ATOM 980 C CB . ASN A 1 144 ? 60.425 59.148 27.146 1.00 26.00 ? 144 ASN A CB 1 ATOM 981 C CG . ASN A 1 144 ? 59.673 58.291 28.153 1.00 29.79 ? 144 ASN A CG 1 ATOM 982 O OD1 . ASN A 1 144 ? 58.444 58.382 28.262 1.00 33.61 ? 144 ASN A OD1 1 ATOM 983 N ND2 . ASN A 1 144 ? 60.399 57.424 28.867 1.00 29.79 ? 144 ASN A ND2 1 ATOM 984 N N . LYS A 1 145 ? 58.144 59.340 24.937 1.00 20.94 ? 145 LYS A N 1 ATOM 985 C CA . LYS A 1 145 ? 56.763 59.157 24.511 1.00 19.82 ? 145 LYS A CA 1 ATOM 986 C C . LYS A 1 145 ? 56.718 58.361 23.199 1.00 19.64 ? 145 LYS A C 1 ATOM 987 O O . LYS A 1 145 ? 55.795 57.554 22.983 1.00 18.25 ? 145 LYS A O 1 ATOM 988 C CB . LYS A 1 145 ? 56.058 60.504 24.340 1.00 21.63 ? 145 LYS A CB 1 ATOM 989 C CG . LYS A 1 145 ? 55.903 61.280 25.645 1.00 24.51 ? 145 LYS A CG 1 ATOM 990 C CD . LYS A 1 145 ? 55.398 60.415 26.750 1.00 26.54 ? 145 LYS A CD 1 ATOM 991 C CE . LYS A 1 145 ? 55.216 61.231 28.033 1.00 27.86 ? 145 LYS A CE 1 ATOM 992 N NZ . LYS A 1 145 ? 54.593 60.300 29.016 1.00 30.63 ? 145 LYS A NZ 1 ATOM 993 N N . LYS A 1 146 ? 57.698 58.549 22.316 1.00 17.81 ? 146 LYS A N 1 ATOM 994 C CA . LYS A 1 146 ? 57.666 57.748 21.087 1.00 18.57 ? 146 LYS A CA 1 ATOM 995 C C . LYS A 1 146 ? 57.709 56.255 21.444 1.00 16.64 ? 146 LYS A C 1 ATOM 996 O O . LYS A 1 146 ? 56.992 55.425 20.869 1.00 16.51 ? 146 LYS A O 1 ATOM 997 C CB . LYS A 1 146 ? 58.835 58.084 20.155 1.00 17.56 ? 146 LYS A CB 1 ATOM 998 C CG . LYS A 1 146 ? 58.752 59.486 19.528 1.00 21.18 ? 146 LYS A CG 1 ATOM 999 C CD . LYS A 1 146 ? 59.859 59.735 18.518 1.00 21.65 ? 146 LYS A CD 1 ATOM 1000 C CE . LYS A 1 146 ? 59.857 61.168 18.042 1.00 25.35 ? 146 LYS A CE 1 ATOM 1001 N NZ . LYS A 1 146 ? 60.970 61.276 17.066 1.00 28.35 ? 146 LYS A NZ 1 ATOM 1002 N N . LEU A 1 147 ? 58.570 55.904 22.388 1.00 16.72 ? 147 LEU A N 1 ATOM 1003 C CA . LEU A 1 147 ? 58.690 54.518 22.768 1.00 16.08 ? 147 LEU A CA 1 ATOM 1004 C C . LEU A 1 147 ? 57.391 54.007 23.408 1.00 15.43 ? 147 LEU A C 1 ATOM 1005 O O . LEU A 1 147 ? 56.970 52.895 23.112 1.00 15.78 ? 147 LEU A O 1 ATOM 1006 C CB . LEU A 1 147 ? 59.903 54.332 23.711 1.00 18.61 ? 147 LEU A CB 1 ATOM 1007 C CG . LEU A 1 147 ? 61.304 54.410 23.084 1.00 20.15 ? 147 LEU A CG 1 ATOM 1008 C CD1 . LEU A 1 147 ? 62.389 54.387 24.163 1.00 22.84 ? 147 LEU A CD1 1 ATOM 1009 C CD2 . LEU A 1 147 ? 61.469 53.226 22.144 1.00 21.88 ? 147 LEU A CD2 1 ATOM 1010 N N . GLN A 1 148 ? 56.764 54.820 24.262 1.00 15.98 ? 148 GLN A N 1 ATOM 1011 C CA . GLN A 1 148 ? 55.500 54.405 24.834 1.00 14.16 ? 148 GLN A CA 1 ATOM 1012 C C . GLN A 1 148 ? 54.432 54.203 23.740 1.00 13.22 ? 148 GLN A C 1 ATOM 1013 O O . GLN A 1 148 ? 53.604 53.260 23.841 1.00 12.78 ? 148 GLN A O 1 ATOM 1014 C CB . GLN A 1 148 ? 54.985 55.464 25.793 1.00 16.18 ? 148 GLN A CB 1 ATOM 1015 C CG . GLN A 1 148 ? 55.760 55.614 27.043 1.00 20.04 ? 148 GLN A CG 1 ATOM 1016 C CD . GLN A 1 148 ? 54.999 56.458 27.998 1.00 22.58 ? 148 GLN A CD 1 ATOM 1017 O OE1 . GLN A 1 148 ? 53.947 57.041 27.654 1.00 26.19 ? 148 GLN A OE1 1 ATOM 1018 N NE2 . GLN A 1 148 ? 55.491 56.525 29.214 1.00 24.20 ? 148 GLN A NE2 1 ATOM 1019 N N . MET A 1 149 ? 54.448 55.069 22.719 1.00 13.81 ? 149 MET A N 1 ATOM 1020 C CA . MET A 1 149 ? 53.455 54.985 21.619 1.00 12.80 ? 149 MET A CA 1 ATOM 1021 C C . MET A 1 149 ? 53.666 53.718 20.792 1.00 14.29 ? 149 MET A C 1 ATOM 1022 O O . MET A 1 149 ? 52.709 52.995 20.494 1.00 11.25 ? 149 MET A O 1 ATOM 1023 C CB . MET A 1 149 ? 53.542 56.262 20.722 1.00 13.73 ? 149 MET A CB 1 ATOM 1024 C CG . MET A 1 149 ? 52.540 56.279 19.566 1.00 11.27 ? 149 MET A CG 1 ATOM 1025 S SD . MET A 1 149 ? 50.870 56.387 20.153 1.00 15.84 ? 149 MET A SD 1 ATOM 1026 C CE . MET A 1 149 ? 50.624 58.085 20.566 1.00 18.27 ? 149 MET A CE 1 ATOM 1027 N N . LYS A 1 150 ? 54.932 53.438 20.462 1.00 13.07 ? 150 LYS A N 1 ATOM 1028 C CA . LYS A 1 150 ? 55.271 52.231 19.697 1.00 12.41 ? 150 LYS A CA 1 ATOM 1029 C C . LYS A 1 150 ? 54.831 51.005 20.470 1.00 13.61 ? 150 LYS A C 1 ATOM 1030 O O . LYS A 1 150 ? 54.334 50.043 19.892 1.00 13.39 ? 150 LYS A O 1 ATOM 1031 C CB . LYS A 1 150 ? 56.778 52.157 19.387 1.00 12.66 ? 150 LYS A CB 1 ATOM 1032 C CG . LYS A 1 150 ? 57.154 53.175 18.276 1.00 16.45 ? 150 LYS A CG 1 ATOM 1033 C CD . LYS A 1 150 ? 58.519 52.873 17.712 1.00 21.91 ? 150 LYS A CD 1 ATOM 1034 C CE . LYS A 1 150 ? 59.579 53.345 18.654 1.00 25.42 ? 150 LYS A CE 1 ATOM 1035 N NZ . LYS A 1 150 ? 60.942 53.112 18.074 1.00 27.03 ? 150 LYS A NZ 1 ATOM 1036 N N . SER A 1 151 ? 54.967 51.069 21.797 1.00 13.82 ? 151 SER A N 1 ATOM 1037 C CA . SER A 1 151 ? 54.570 49.941 22.629 1.00 14.48 ? 151 SER A CA 1 ATOM 1038 C C . SER A 1 151 ? 53.043 49.692 22.661 1.00 14.25 ? 151 SER A C 1 ATOM 1039 O O . SER A 1 151 ? 52.615 48.538 22.653 1.00 14.89 ? 151 SER A O 1 ATOM 1040 C CB . SER A 1 151 ? 55.136 50.097 24.045 1.00 14.78 ? 151 SER A CB 1 ATOM 1041 O OG . SER A 1 151 ? 54.896 48.904 24.759 1.00 20.01 ? 151 SER A OG 1 ATOM 1042 N N . ILE A 1 152 ? 52.214 50.739 22.672 1.00 12.61 ? 152 ILE A N 1 ATOM 1043 C CA . ILE A 1 152 ? 50.770 50.529 22.654 1.00 11.86 ? 152 ILE A CA 1 ATOM 1044 C C . ILE A 1 152 ? 50.276 50.164 21.280 1.00 12.29 ? 152 ILE A C 1 ATOM 1045 O O . ILE A 1 152 ? 49.216 49.596 21.157 1.00 13.19 ? 152 ILE A O 1 ATOM 1046 C CB . ILE A 1 152 ? 49.913 51.706 23.247 1.00 14.73 ? 152 ILE A CB 1 ATOM 1047 C CG1 . ILE A 1 152 ? 50.224 53.056 22.643 1.00 12.61 ? 152 ILE A CG1 1 ATOM 1048 C CG2 . ILE A 1 152 ? 50.133 51.742 24.750 1.00 13.50 ? 152 ILE A CG2 1 ATOM 1049 C CD1 . ILE A 1 152 ? 49.078 54.038 22.848 1.00 12.27 ? 152 ILE A CD1 1 ATOM 1050 N N . VAL A 1 153 ? 51.068 50.440 20.254 1.00 11.46 ? 153 VAL A N 1 ATOM 1051 C CA . VAL A 1 153 ? 50.698 49.998 18.934 1.00 12.62 ? 153 VAL A CA 1 ATOM 1052 C C . VAL A 1 153 ? 51.107 48.510 18.818 1.00 13.08 ? 153 VAL A C 1 ATOM 1053 O O . VAL A 1 153 ? 50.296 47.661 18.443 1.00 13.10 ? 153 VAL A O 1 ATOM 1054 C CB . VAL A 1 153 ? 51.363 50.875 17.870 1.00 12.63 ? 153 VAL A CB 1 ATOM 1055 C CG1 . VAL A 1 153 ? 51.163 50.238 16.462 1.00 16.38 ? 153 VAL A CG1 1 ATOM 1056 C CG2 . VAL A 1 153 ? 50.696 52.234 17.870 1.00 12.89 ? 153 VAL A CG2 1 ATOM 1057 N N . LYS A 1 154 ? 52.342 48.185 19.216 1.00 14.59 ? 154 LYS A N 1 ATOM 1058 C CA . LYS A 1 154 ? 52.819 46.804 19.119 1.00 15.89 ? 154 LYS A CA 1 ATOM 1059 C C . LYS A 1 154 ? 51.983 45.818 19.919 1.00 15.87 ? 154 LYS A C 1 ATOM 1060 O O . LYS A 1 154 ? 51.765 44.690 19.486 1.00 15.92 ? 154 LYS A O 1 ATOM 1061 C CB . LYS A 1 154 ? 54.263 46.746 19.569 1.00 19.88 ? 154 LYS A CB 1 ATOM 1062 C CG . LYS A 1 154 ? 54.879 45.373 19.390 1.00 23.49 ? 154 LYS A CG 1 ATOM 1063 C CD . LYS A 1 154 ? 56.353 45.558 19.092 1.00 28.62 ? 154 LYS A CD 1 ATOM 1064 C CE . LYS A 1 154 ? 57.043 46.274 20.205 1.00 31.50 ? 154 LYS A CE 1 ATOM 1065 N NZ . LYS A 1 154 ? 58.457 46.587 19.822 1.00 34.31 ? 154 LYS A NZ 1 ATOM 1066 N N . ASN A 1 155 ? 51.491 46.238 21.076 1.00 15.99 ? 155 ASN A N 1 ATOM 1067 C CA . ASN A 1 155 ? 50.655 45.403 21.930 1.00 16.81 ? 155 ASN A CA 1 ATOM 1068 C C . ASN A 1 155 ? 49.163 45.370 21.559 1.00 15.50 ? 155 ASN A C 1 ATOM 1069 O O . ASN A 1 155 ? 48.386 44.771 22.273 1.00 17.71 ? 155 ASN A O 1 ATOM 1070 C CB . ASN A 1 155 ? 50.836 45.788 23.420 1.00 19.46 ? 155 ASN A CB 1 ATOM 1071 C CG . ASN A 1 155 ? 49.952 47.003 23.852 1.00 23.15 ? 155 ASN A CG 1 ATOM 1072 O OD1 . ASN A 1 155 ? 49.170 47.532 23.036 1.00 24.75 ? 155 ASN A OD1 1 ATOM 1073 N ND2 . ASN A 1 155 ? 50.074 47.441 25.128 1.00 21.07 ? 155 ASN A ND2 1 ATOM 1074 N N . GLY A 1 156 ? 48.739 46.024 20.472 1.00 13.73 ? 156 GLY A N 1 ATOM 1075 C CA . GLY A 1 156 ? 47.344 45.936 20.099 1.00 12.62 ? 156 GLY A CA 1 ATOM 1076 C C . GLY A 1 156 ? 46.331 46.877 20.719 1.00 11.91 ? 156 GLY A C 1 ATOM 1077 O O . GLY A 1 156 ? 45.165 46.835 20.307 1.00 15.32 ? 156 GLY A O 1 ATOM 1078 N N . GLN A 1 157 ? 46.722 47.799 21.605 1.00 10.84 ? 157 GLN A N 1 ATOM 1079 C CA . GLN A 1 157 ? 45.717 48.708 22.176 1.00 10.20 ? 157 GLN A CA 1 ATOM 1080 C C . GLN A 1 157 ? 45.321 49.819 21.183 1.00 9.59 ? 157 GLN A C 1 ATOM 1081 O O . GLN A 1 157 ? 44.135 50.138 21.055 1.00 10.59 ? 157 GLN A O 1 ATOM 1082 C CB . GLN A 1 157 ? 46.260 49.351 23.427 1.00 11.30 ? 157 GLN A CB 1 ATOM 1083 C CG . GLN A 1 157 ? 46.242 48.468 24.606 1.00 13.04 ? 157 GLN A CG 1 ATOM 1084 C CD . GLN A 1 157 ? 46.734 49.240 25.822 1.00 11.56 ? 157 GLN A CD 1 ATOM 1085 O OE1 . GLN A 1 157 ? 47.918 49.227 26.159 1.00 14.23 ? 157 GLN A OE1 1 ATOM 1086 N NE2 . GLN A 1 157 ? 45.848 49.967 26.425 1.00 11.26 ? 157 GLN A NE2 1 ATOM 1087 N N . LEU A 1 158 ? 46.311 50.417 20.518 1.00 10.43 ? 158 LEU A N 1 ATOM 1088 C CA . LEU A 1 158 ? 46.077 51.439 19.505 1.00 10.62 ? 158 LEU A CA 1 ATOM 1089 C C . LEU A 1 158 ? 46.227 50.737 18.152 1.00 10.41 ? 158 LEU A C 1 ATOM 1090 O O A LEU A 1 158 ? 47.285 50.149 17.854 0.50 11.16 ? 158 LEU A O 1 ATOM 1091 O O B LEU A 1 158 ? 47.387 50.449 17.795 0.50 9.50 ? 158 LEU A O 1 ATOM 1092 C CB . LEU A 1 158 ? 47.110 52.571 19.642 1.00 12.48 ? 158 LEU A CB 1 ATOM 1093 C CG A LEU A 1 158 ? 46.981 53.849 18.799 0.50 14.09 ? 158 LEU A CG 1 ATOM 1094 C CG B LEU A 1 158 ? 47.043 53.702 18.631 0.50 11.67 ? 158 LEU A CG 1 ATOM 1095 C CD1 A LEU A 1 158 ? 48.239 54.685 19.009 0.50 15.94 ? 158 LEU A CD1 1 ATOM 1096 C CD1 B LEU A 1 158 ? 45.679 54.343 18.593 0.50 11.09 ? 158 LEU A CD1 1 ATOM 1097 C CD2 A LEU A 1 158 ? 46.852 53.557 17.345 0.50 13.80 ? 158 LEU A CD2 1 ATOM 1098 C CD2 B LEU A 1 158 ? 48.123 54.750 18.910 0.50 13.34 ? 158 LEU A CD2 1 ATOM 1099 N N . GLU A 1 159 ? 45.200 50.804 17.316 1.00 8.49 ? 159 GLU A N 1 ATOM 1100 C CA . GLU A 1 159 ? 45.289 50.141 16.023 1.00 8.18 ? 159 GLU A CA 1 ATOM 1101 C C . GLU A 1 159 ? 44.977 51.130 14.896 1.00 7.99 ? 159 GLU A C 1 ATOM 1102 O O . GLU A 1 159 ? 43.957 51.816 14.940 1.00 8.25 ? 159 GLU A O 1 ATOM 1103 C CB . GLU A 1 159 ? 44.260 49.020 15.944 1.00 10.11 ? 159 GLU A CB 1 ATOM 1104 C CG . GLU A 1 159 ? 44.272 48.254 14.597 1.00 10.42 ? 159 GLU A CG 1 ATOM 1105 C CD . GLU A 1 159 ? 43.298 47.129 14.687 1.00 13.29 ? 159 GLU A CD 1 ATOM 1106 O OE1 . GLU A 1 159 ? 43.607 46.115 15.407 1.00 11.39 ? 159 GLU A OE1 1 ATOM 1107 O OE2 . GLU A 1 159 ? 42.221 47.278 14.071 1.00 10.91 ? 159 GLU A OE2 1 ATOM 1108 N N . PHE A 1 160 ? 45.825 51.163 13.848 1.00 7.96 ? 160 PHE A N 1 ATOM 1109 C CA . PHE A 1 160 ? 45.554 52.020 12.726 1.00 6.54 ? 160 PHE A CA 1 ATOM 1110 C C . PHE A 1 160 ? 44.637 51.296 11.782 1.00 7.00 ? 160 PHE A C 1 ATOM 1111 O O . PHE A 1 160 ? 44.778 50.106 11.499 1.00 7.91 ? 160 PHE A O 1 ATOM 1112 C CB . PHE A 1 160 ? 46.882 52.407 12.052 1.00 6.40 ? 160 PHE A CB 1 ATOM 1113 C CG . PHE A 1 160 ? 47.772 53.247 12.946 1.00 6.94 ? 160 PHE A CG 1 ATOM 1114 C CD1 . PHE A 1 160 ? 47.458 54.612 13.163 1.00 8.88 ? 160 PHE A CD1 1 ATOM 1115 C CD2 . PHE A 1 160 ? 48.877 52.655 13.603 1.00 10.24 ? 160 PHE A CD2 1 ATOM 1116 C CE1 . PHE A 1 160 ? 48.247 55.357 14.043 1.00 11.28 ? 160 PHE A CE1 1 ATOM 1117 C CE2 . PHE A 1 160 ? 49.660 53.422 14.487 1.00 12.97 ? 160 PHE A CE2 1 ATOM 1118 C CZ . PHE A 1 160 ? 49.331 54.755 14.701 1.00 11.99 ? 160 PHE A CZ 1 ATOM 1119 N N . VAL A 1 161 ? 43.639 52.041 11.320 1.00 5.96 ? 161 VAL A N 1 ATOM 1120 C CA . VAL A 1 161 ? 42.669 51.546 10.350 1.00 7.36 ? 161 VAL A CA 1 ATOM 1121 C C . VAL A 1 161 ? 42.898 52.372 9.077 1.00 6.37 ? 161 VAL A C 1 ATOM 1122 O O . VAL A 1 161 ? 42.993 53.608 9.131 1.00 7.40 ? 161 VAL A O 1 ATOM 1123 C CB . VAL A 1 161 ? 41.209 51.663 10.921 1.00 9.02 ? 161 VAL A CB 1 ATOM 1124 C CG1 . VAL A 1 161 ? 41.080 50.603 12.132 1.00 8.14 ? 161 VAL A CG1 1 ATOM 1125 C CG2 . VAL A 1 161 ? 40.921 53.099 11.474 1.00 8.45 ? 161 VAL A CG2 1 ATOM 1126 N N . THR A 1 162 ? 42.946 51.662 7.930 1.00 6.21 ? 162 THR A N 1 ATOM 1127 C CA . THR A 1 162 ? 43.295 52.185 6.589 1.00 8.15 ? 162 THR A CA 1 ATOM 1128 C C . THR A 1 162 ? 44.776 52.666 6.539 1.00 7.26 ? 162 THR A C 1 ATOM 1129 O O . THR A 1 162 ? 45.608 52.099 5.764 1.00 7.03 ? 162 THR A O 1 ATOM 1130 C CB . THR A 1 162 ? 42.407 53.351 6.089 1.00 6.42 ? 162 THR A CB 1 ATOM 1131 O OG1 . THR A 1 162 ? 41.035 52.977 6.119 1.00 9.39 ? 162 THR A OG1 1 ATOM 1132 C CG2 . THR A 1 162 ? 42.715 53.589 4.591 1.00 7.71 ? 162 THR A CG2 1 ATOM 1133 N N . GLY A 1 163 ? 45.093 53.691 7.352 1.00 7.11 ? 163 GLY A N 1 ATOM 1134 C CA . GLY A 1 163 ? 46.453 54.201 7.396 1.00 7.31 ? 163 GLY A CA 1 ATOM 1135 C C . GLY A 1 163 ? 46.799 55.157 6.261 1.00 7.64 ? 163 GLY A C 1 ATOM 1136 O O . GLY A 1 163 ? 47.987 55.323 5.950 1.00 8.88 ? 163 GLY A O 1 ATOM 1137 N N . GLY A 1 164 ? 45.795 55.703 5.598 1.00 5.86 ? 164 GLY A N 1 ATOM 1138 C CA . GLY A 1 164 ? 46.080 56.704 4.563 1.00 7.51 ? 164 GLY A CA 1 ATOM 1139 C C . GLY A 1 164 ? 46.383 58.033 5.227 1.00 7.40 ? 164 GLY A C 1 ATOM 1140 O O . GLY A 1 164 ? 46.098 58.242 6.441 1.00 6.78 ? 164 GLY A O 1 ATOM 1141 N N . TRP A 1 165 ? 47.016 58.928 4.456 1.00 6.53 ? 165 TRP A N 1 ATOM 1142 C CA . TRP A 1 165 ? 47.246 60.288 4.957 1.00 6.72 ? 165 TRP A CA 1 ATOM 1143 C C . TRP A 1 165 ? 45.896 60.943 5.440 1.00 7.67 ? 165 TRP A C 1 ATOM 1144 O O . TRP A 1 165 ? 45.890 61.655 6.423 1.00 7.21 ? 165 TRP A O 1 ATOM 1145 C CB . TRP A 1 165 ? 47.905 61.064 3.837 1.00 5.83 ? 165 TRP A CB 1 ATOM 1146 C CG . TRP A 1 165 ? 48.684 62.255 4.279 1.00 7.60 ? 165 TRP A CG 1 ATOM 1147 C CD1 . TRP A 1 165 ? 48.435 63.555 3.982 1.00 10.14 ? 165 TRP A CD1 1 ATOM 1148 C CD2 . TRP A 1 165 ? 49.881 62.229 5.061 1.00 10.18 ? 165 TRP A CD2 1 ATOM 1149 N NE1 . TRP A 1 165 ? 49.429 64.378 4.549 1.00 10.67 ? 165 TRP A NE1 1 ATOM 1150 C CE2 . TRP A 1 165 ? 50.321 63.587 5.210 1.00 10.57 ? 165 TRP A CE2 1 ATOM 1151 C CE3 . TRP A 1 165 ? 50.630 61.202 5.660 1.00 10.09 ? 165 TRP A CE3 1 ATOM 1152 C CZ2 . TRP A 1 165 ? 51.484 63.937 5.951 1.00 10.72 ? 165 TRP A CZ2 1 ATOM 1153 C CZ3 . TRP A 1 165 ? 51.800 61.553 6.381 1.00 10.25 ? 165 TRP A CZ3 1 ATOM 1154 C CH2 . TRP A 1 165 ? 52.203 62.936 6.510 1.00 11.69 ? 165 TRP A CH2 1 ATOM 1155 N N . VAL A 1 166 ? 44.799 60.605 4.733 1.00 7.20 ? 166 VAL A N 1 ATOM 1156 C CA . VAL A 1 166 ? 43.447 61.102 5.020 1.00 8.08 ? 166 VAL A CA 1 ATOM 1157 C C . VAL A 1 166 ? 42.438 60.003 4.826 1.00 7.13 ? 166 VAL A C 1 ATOM 1158 O O . VAL A 1 166 ? 42.837 58.852 4.539 1.00 7.02 ? 166 VAL A O 1 ATOM 1159 C CB . VAL A 1 166 ? 43.029 62.263 4.030 1.00 6.26 ? 166 VAL A CB 1 ATOM 1160 C CG1 . VAL A 1 166 ? 44.070 63.440 4.077 1.00 7.88 ? 166 VAL A CG1 1 ATOM 1161 C CG2 . VAL A 1 166 ? 42.982 61.768 2.586 1.00 10.14 ? 166 VAL A CG2 1 ATOM 1162 N N . MET A 1 167 ? 41.167 60.314 5.025 1.00 7.31 ? 167 MET A N 1 ATOM 1163 C CA . MET A 1 167 ? 40.064 59.327 4.713 1.00 7.48 ? 167 MET A CA 1 ATOM 1164 C C . MET A 1 167 ? 39.536 60.084 3.485 1.00 6.74 ? 167 MET A C 1 ATOM 1165 O O . MET A 1 167 ? 38.768 61.061 3.613 1.00 6.51 ? 167 MET A O 1 ATOM 1166 C CB . MET A 1 167 ? 39.063 59.326 5.830 1.00 6.86 ? 167 MET A CB 1 ATOM 1167 C CG . MET A 1 167 ? 37.798 58.629 5.509 1.00 6.00 ? 167 MET A CG 1 ATOM 1168 S SD . MET A 1 167 ? 36.600 58.613 6.931 1.00 8.29 ? 167 MET A SD 1 ATOM 1169 C CE . MET A 1 167 ? 37.618 57.849 8.279 1.00 7.45 ? 167 MET A CE 1 ATOM 1170 N N . PRO A 1 168 ? 39.929 59.662 2.267 1.00 6.42 ? 168 PRO A N 1 ATOM 1171 C CA . PRO A 1 168 ? 39.514 60.407 1.102 1.00 7.34 ? 168 PRO A CA 1 ATOM 1172 C C . PRO A 1 168 ? 38.095 60.427 0.675 1.00 5.79 ? 168 PRO A C 1 ATOM 1173 O O . PRO A 1 168 ? 37.330 59.515 0.902 1.00 6.04 ? 168 PRO A O 1 ATOM 1174 C CB . PRO A 1 168 ? 40.424 59.830 -0.023 1.00 6.91 ? 168 PRO A CB 1 ATOM 1175 C CG . PRO A 1 168 ? 40.485 58.362 0.386 1.00 5.09 ? 168 PRO A CG 1 ATOM 1176 C CD . PRO A 1 168 ? 40.664 58.432 1.893 1.00 5.63 ? 168 PRO A CD 1 ATOM 1177 N N . ASP A 1 169 ? 37.776 61.524 -0.015 1.00 7.64 ? 169 ASP A N 1 ATOM 1178 C CA . ASP A 1 169 ? 36.533 61.564 -0.779 1.00 8.05 ? 169 ASP A CA 1 ATOM 1179 C C . ASP A 1 169 ? 36.638 60.372 -1.771 1.00 7.68 ? 169 ASP A C 1 ATOM 1180 O O . ASP A 1 169 ? 37.739 60.033 -2.242 1.00 6.32 ? 169 ASP A O 1 ATOM 1181 C CB . ASP A 1 169 ? 36.535 62.881 -1.590 1.00 7.36 ? 169 ASP A CB 1 ATOM 1182 C CG . ASP A 1 169 ? 35.393 62.960 -2.594 1.00 7.36 ? 169 ASP A CG 1 ATOM 1183 O OD1 . ASP A 1 169 ? 34.294 62.407 -2.280 1.00 8.52 ? 169 ASP A OD1 1 ATOM 1184 O OD2 . ASP A 1 169 ? 35.546 63.520 -3.700 1.00 7.72 ? 169 ASP A OD2 1 ATOM 1185 N N . GLU A 1 170 ? 35.506 59.776 -2.129 1.00 6.67 ? 170 GLU A N 1 ATOM 1186 C CA . GLU A 1 170 ? 35.504 58.662 -3.073 1.00 7.07 ? 170 GLU A CA 1 ATOM 1187 C C . GLU A 1 170 ? 34.788 59.041 -4.374 1.00 5.76 ? 170 GLU A C 1 ATOM 1188 O O . GLU A 1 170 ? 34.814 58.248 -5.291 1.00 6.10 ? 170 GLU A O 1 ATOM 1189 C CB . GLU A 1 170 ? 34.861 57.438 -2.414 1.00 6.69 ? 170 GLU A CB 1 ATOM 1190 C CG . GLU A 1 170 ? 35.656 57.010 -1.203 1.00 6.84 ? 170 GLU A CG 1 ATOM 1191 C CD . GLU A 1 170 ? 35.087 55.773 -0.490 1.00 7.00 ? 170 GLU A CD 1 ATOM 1192 O OE1 . GLU A 1 170 ? 34.292 55.040 -1.096 1.00 8.17 ? 170 GLU A OE1 1 ATOM 1193 O OE2 . GLU A 1 170 ? 35.482 55.556 0.698 1.00 7.59 ? 170 GLU A OE2 1 ATOM 1194 N N . ALA A 1 171 ? 34.155 60.249 -4.450 1.00 6.10 ? 171 ALA A N 1 ATOM 1195 C CA . ALA A 1 171 ? 33.450 60.679 -5.667 1.00 7.41 ? 171 ALA A CA 1 ATOM 1196 C C . ALA A 1 171 ? 34.330 61.454 -6.699 1.00 4.94 ? 171 ALA A C 1 ATOM 1197 O O . ALA A 1 171 ? 34.374 61.092 -7.858 1.00 7.97 ? 171 ALA A O 1 ATOM 1198 C CB . ALA A 1 171 ? 32.251 61.553 -5.291 1.00 8.80 ? 171 ALA A CB 1 ATOM 1199 N N . ASN A 1 172 ? 35.034 62.471 -6.211 1.00 7.90 ? 172 ASN A N 1 ATOM 1200 C CA . ASN A 1 172 ? 35.821 63.348 -7.087 1.00 7.22 ? 172 ASN A CA 1 ATOM 1201 C C . ASN A 1 172 ? 37.273 62.988 -7.243 1.00 7.98 ? 172 ASN A C 1 ATOM 1202 O O . ASN A 1 172 ? 37.948 63.429 -8.200 1.00 6.02 ? 172 ASN A O 1 ATOM 1203 C CB . ASN A 1 172 ? 35.751 64.772 -6.573 1.00 7.99 ? 172 ASN A CB 1 ATOM 1204 C CG . ASN A 1 172 ? 34.346 65.298 -6.423 1.00 9.03 ? 172 ASN A CG 1 ATOM 1205 O OD1 . ASN A 1 172 ? 33.664 65.508 -7.425 1.00 9.78 ? 172 ASN A OD1 1 ATOM 1206 N ND2 . ASN A 1 172 ? 33.948 65.546 -5.180 1.00 7.70 ? 172 ASN A ND2 1 ATOM 1207 N N . SER A 1 173 ? 37.762 62.145 -6.331 1.00 7.11 ? 173 SER A N 1 ATOM 1208 C CA . SER A 1 173 ? 39.189 61.784 -6.360 1.00 5.68 ? 173 SER A CA 1 ATOM 1209 C C . SER A 1 173 ? 39.597 60.860 -7.476 1.00 7.68 ? 173 SER A C 1 ATOM 1210 O O . SER A 1 173 ? 38.857 59.962 -7.881 1.00 8.50 ? 173 SER A O 1 ATOM 1211 C CB . SER A 1 173 ? 39.506 61.124 -4.992 1.00 6.66 ? 173 SER A CB 1 ATOM 1212 O OG . SER A 1 173 ? 38.563 60.014 -4.812 1.00 6.32 ? 173 SER A OG 1 ATOM 1213 N N . HIS A 1 174 ? 40.783 61.143 -8.039 1.00 6.76 ? 174 HIS A N 1 ATOM 1214 C CA . HIS A 1 174 ? 41.332 60.274 -9.049 1.00 6.54 ? 174 HIS A CA 1 ATOM 1215 C C . HIS A 1 174 ? 41.956 59.056 -8.339 1.00 4.51 ? 174 HIS A C 1 ATOM 1216 O O . HIS A 1 174 ? 42.581 59.229 -7.290 1.00 5.75 ? 174 HIS A O 1 ATOM 1217 C CB . HIS A 1 174 ? 42.392 61.009 -9.874 1.00 7.31 ? 174 HIS A CB 1 ATOM 1218 C CG . HIS A 1 174 ? 42.614 60.375 -11.212 1.00 7.57 ? 174 HIS A CG 1 ATOM 1219 N ND1 . HIS A 1 174 ? 43.307 59.184 -11.347 1.00 8.18 ? 174 HIS A ND1 1 ATOM 1220 C CD2 . HIS A 1 174 ? 42.188 60.713 -12.458 1.00 7.54 ? 174 HIS A CD2 1 ATOM 1221 C CE1 . HIS A 1 174 ? 43.298 58.829 -12.619 1.00 9.81 ? 174 HIS A CE1 1 ATOM 1222 N NE2 . HIS A 1 174 ? 42.612 59.730 -13.308 1.00 8.68 ? 174 HIS A NE2 1 ATOM 1223 N N . TRP A 1 175 ? 41.764 57.865 -8.880 1.00 4.53 ? 175 TRP A N 1 ATOM 1224 C CA . TRP A 1 175 ? 42.366 56.687 -8.255 1.00 5.91 ? 175 TRP A CA 1 ATOM 1225 C C . TRP A 1 175 ? 43.881 56.873 -8.007 1.00 6.06 ? 175 TRP A C 1 ATOM 1226 O O . TRP A 1 175 ? 44.430 56.360 -7.012 1.00 5.98 ? 175 TRP A O 1 ATOM 1227 C CB . TRP A 1 175 ? 42.069 55.415 -9.096 1.00 4.75 ? 175 TRP A CB 1 ATOM 1228 C CG . TRP A 1 175 ? 42.939 55.263 -10.337 1.00 4.32 ? 175 TRP A CG 1 ATOM 1229 C CD1 . TRP A 1 175 ? 42.616 55.583 -11.672 1.00 6.01 ? 175 TRP A CD1 1 ATOM 1230 C CD2 . TRP A 1 175 ? 44.227 54.664 -10.390 1.00 6.29 ? 175 TRP A CD2 1 ATOM 1231 N NE1 . TRP A 1 175 ? 43.658 55.226 -12.508 1.00 6.61 ? 175 TRP A NE1 1 ATOM 1232 C CE2 . TRP A 1 175 ? 44.654 54.642 -11.751 1.00 8.70 ? 175 TRP A CE2 1 ATOM 1233 C CE3 . TRP A 1 175 ? 45.063 54.107 -9.406 1.00 10.69 ? 175 TRP A CE3 1 ATOM 1234 C CZ2 . TRP A 1 175 ? 45.908 54.079 -12.141 1.00 8.54 ? 175 TRP A CZ2 1 ATOM 1235 C CZ3 . TRP A 1 175 ? 46.301 53.556 -9.810 1.00 8.99 ? 175 TRP A CZ3 1 ATOM 1236 C CH2 . TRP A 1 175 ? 46.701 53.549 -11.151 1.00 9.46 ? 175 TRP A CH2 1 ATOM 1237 N N . ARG A 1 176 ? 44.575 57.574 -8.936 1.00 5.70 ? 176 ARG A N 1 ATOM 1238 C CA . ARG A 1 176 ? 46.021 57.738 -8.764 1.00 6.14 ? 176 ARG A CA 1 ATOM 1239 C C . ARG A 1 176 ? 46.288 58.506 -7.456 1.00 5.85 ? 176 ARG A C 1 ATOM 1240 O O . ARG A 1 176 ? 47.310 58.215 -6.778 1.00 7.05 ? 176 ARG A O 1 ATOM 1241 C CB . ARG A 1 176 ? 46.575 58.537 -9.976 1.00 7.28 ? 176 ARG A CB 1 ATOM 1242 C CG . ARG A 1 176 ? 46.634 57.695 -11.228 1.00 10.60 ? 176 ARG A CG 1 ATOM 1243 C CD . ARG A 1 176 ? 46.620 58.475 -12.565 1.00 9.92 ? 176 ARG A CD 1 ATOM 1244 N NE . ARG A 1 176 ? 47.728 59.401 -12.611 1.00 9.48 ? 176 ARG A NE 1 ATOM 1245 C CZ . ARG A 1 176 ? 47.867 60.293 -13.596 1.00 6.96 ? 176 ARG A CZ 1 ATOM 1246 N NH1 . ARG A 1 176 ? 46.958 60.309 -14.614 1.00 8.67 ? 176 ARG A NH1 1 ATOM 1247 N NH2 . ARG A 1 176 ? 48.848 61.177 -13.549 1.00 9.97 ? 176 ARG A NH2 1 ATOM 1248 N N . ASN A 1 177 ? 45.438 59.476 -7.108 1.00 5.85 ? 177 ASN A N 1 ATOM 1249 C CA . ASN A 1 177 ? 45.686 60.237 -5.880 1.00 5.09 ? 177 ASN A CA 1 ATOM 1250 C C . ASN A 1 177 ? 45.179 59.512 -4.611 1.00 7.97 ? 177 ASN A C 1 ATOM 1251 O O . ASN A 1 177 ? 45.674 59.726 -3.489 1.00 6.74 ? 177 ASN A O 1 ATOM 1252 C CB . ASN A 1 177 ? 45.062 61.621 -5.965 1.00 7.88 ? 177 ASN A CB 1 ATOM 1253 C CG . ASN A 1 177 ? 45.742 62.493 -7.019 1.00 7.94 ? 177 ASN A CG 1 ATOM 1254 O OD1 . ASN A 1 177 ? 46.902 62.277 -7.358 1.00 8.33 ? 177 ASN A OD1 1 ATOM 1255 N ND2 . ASN A 1 177 ? 45.017 63.466 -7.551 1.00 10.18 ? 177 ASN A ND2 1 ATOM 1256 N N . VAL A 1 178 ? 44.176 58.660 -4.823 1.00 7.57 ? 178 VAL A N 1 ATOM 1257 C CA . VAL A 1 178 ? 43.729 57.820 -3.701 1.00 7.88 ? 178 VAL A CA 1 ATOM 1258 C C . VAL A 1 178 ? 44.923 56.891 -3.340 1.00 6.25 ? 178 VAL A C 1 ATOM 1259 O O . VAL A 1 178 ? 45.248 56.694 -2.153 1.00 5.79 ? 178 VAL A O 1 ATOM 1260 C CB . VAL A 1 178 ? 42.501 56.957 -4.086 1.00 5.40 ? 178 VAL A CB 1 ATOM 1261 C CG1 . VAL A 1 178 ? 42.162 55.963 -2.957 1.00 6.04 ? 178 VAL A CG1 1 ATOM 1262 C CG2 . VAL A 1 178 ? 41.290 57.835 -4.244 1.00 6.24 ? 178 VAL A CG2 1 ATOM 1263 N N . LEU A 1 179 ? 45.614 56.356 -4.359 1.00 5.22 ? 179 LEU A N 1 ATOM 1264 C CA . LEU A 1 179 ? 46.777 55.492 -4.110 1.00 6.53 ? 179 LEU A CA 1 ATOM 1265 C C . LEU A 1 179 ? 47.925 56.315 -3.529 1.00 7.24 ? 179 LEU A C 1 ATOM 1266 O O . LEU A 1 179 ? 48.562 55.917 -2.524 1.00 7.54 ? 179 LEU A O 1 ATOM 1267 C CB . LEU A 1 179 ? 47.223 54.804 -5.404 1.00 7.33 ? 179 LEU A CB 1 ATOM 1268 C CG . LEU A 1 179 ? 48.584 54.025 -5.310 1.00 6.02 ? 179 LEU A CG 1 ATOM 1269 C CD1 . LEU A 1 179 ? 48.447 52.862 -4.262 1.00 7.23 ? 179 LEU A CD1 1 ATOM 1270 C CD2 . LEU A 1 179 ? 48.920 53.417 -6.698 1.00 9.43 ? 179 LEU A CD2 1 ATOM 1271 N N . LEU A 1 180 ? 48.116 57.532 -4.056 1.00 5.28 ? 180 LEU A N 1 ATOM 1272 C CA . LEU A 1 180 ? 49.216 58.394 -3.580 1.00 7.21 ? 180 LEU A CA 1 ATOM 1273 C C . LEU A 1 180 ? 49.044 58.600 -2.068 1.00 5.53 ? 180 LEU A C 1 ATOM 1274 O O . LEU A 1 180 ? 49.972 58.405 -1.263 1.00 9.21 ? 180 LEU A O 1 ATOM 1275 C CB . LEU A 1 180 ? 49.146 59.759 -4.268 1.00 6.55 ? 180 LEU A CB 1 ATOM 1276 C CG . LEU A 1 180 ? 50.292 60.710 -3.901 1.00 7.61 ? 180 LEU A CG 1 ATOM 1277 C CD1 . LEU A 1 180 ? 51.615 60.213 -4.479 1.00 8.88 ? 180 LEU A CD1 1 ATOM 1278 C CD2 . LEU A 1 180 ? 49.950 62.110 -4.445 1.00 8.75 ? 180 LEU A CD2 1 ATOM 1279 N N . GLN A 1 181 ? 47.847 58.977 -1.618 1.00 8.52 ? 181 GLN A N 1 ATOM 1280 C CA . GLN A 1 181 ? 47.649 59.299 -0.165 1.00 4.54 ? 181 GLN A CA 1 ATOM 1281 C C . GLN A 1 181 ? 47.716 58.036 0.734 1.00 6.74 ? 181 GLN A C 1 ATOM 1282 O O . GLN A 1 181 ? 48.222 58.065 1.862 1.00 5.85 ? 181 GLN A O 1 ATOM 1283 C CB . GLN A 1 181 ? 46.336 60.147 0.009 1.00 6.77 ? 181 GLN A CB 1 ATOM 1284 C CG . GLN A 1 181 ? 44.990 59.437 -0.210 1.00 5.30 ? 181 GLN A CG 1 ATOM 1285 C CD . GLN A 1 181 ? 44.624 58.459 0.971 1.00 7.51 ? 181 GLN A CD 1 ATOM 1286 O OE1 . GLN A 1 181 ? 44.937 58.729 2.145 1.00 6.70 ? 181 GLN A OE1 1 ATOM 1287 N NE2 . GLN A 1 181 ? 43.976 57.329 0.630 1.00 8.34 ? 181 GLN A NE2 1 ATOM 1288 N N . LEU A 1 182 ? 47.219 56.929 0.192 1.00 6.94 ? 182 LEU A N 1 ATOM 1289 C CA . LEU A 1 182 ? 47.292 55.687 0.920 1.00 7.82 ? 182 LEU A CA 1 ATOM 1290 C C . LEU A 1 182 ? 48.759 55.322 1.131 1.00 8.26 ? 182 LEU A C 1 ATOM 1291 O O . LEU A 1 182 ? 49.175 54.998 2.235 1.00 5.82 ? 182 LEU A O 1 ATOM 1292 C CB . LEU A 1 182 ? 46.578 54.564 0.154 1.00 6.28 ? 182 LEU A CB 1 ATOM 1293 C CG . LEU A 1 182 ? 46.661 53.171 0.822 1.00 5.72 ? 182 LEU A CG 1 ATOM 1294 C CD1 . LEU A 1 182 ? 45.897 53.186 2.187 1.00 7.72 ? 182 LEU A CD1 1 ATOM 1295 C CD2 . LEU A 1 182 ? 46.072 52.065 -0.137 1.00 7.14 ? 182 LEU A CD2 1 ATOM 1296 N N . THR A 1 183 ? 49.537 55.493 0.060 1.00 6.25 ? 183 THR A N 1 ATOM 1297 C CA . THR A 1 183 ? 50.956 55.135 0.133 1.00 7.12 ? 183 THR A CA 1 ATOM 1298 C C . THR A 1 183 ? 51.688 56.084 1.061 1.00 8.05 ? 183 THR A C 1 ATOM 1299 O O . THR A 1 183 ? 52.614 55.678 1.797 1.00 7.80 ? 183 THR A O 1 ATOM 1300 C CB . THR A 1 183 ? 51.575 55.232 -1.276 1.00 5.82 ? 183 THR A CB 1 ATOM 1301 O OG1 . THR A 1 183 ? 50.900 54.337 -2.156 1.00 6.78 ? 183 THR A OG1 1 ATOM 1302 C CG2 . THR A 1 183 ? 53.064 54.868 -1.224 1.00 8.83 ? 183 THR A CG2 1 ATOM 1303 N N . GLU A 1 184 ? 51.323 57.357 1.050 1.00 5.67 ? 184 GLU A N 1 ATOM 1304 C CA . GLU A 1 184 ? 52.001 58.311 1.920 1.00 7.07 ? 184 GLU A CA 1 ATOM 1305 C C . GLU A 1 184 ? 51.798 57.938 3.381 1.00 6.63 ? 184 GLU A C 1 ATOM 1306 O O . GLU A 1 184 ? 52.753 57.897 4.203 1.00 9.53 ? 184 GLU A O 1 ATOM 1307 C CB . GLU A 1 184 ? 51.456 59.732 1.688 1.00 7.27 ? 184 GLU A CB 1 ATOM 1308 C CG . GLU A 1 184 ? 52.321 60.891 2.129 1.00 9.91 ? 184 GLU A CG 1 ATOM 1309 C CD . GLU A 1 184 ? 53.710 60.909 1.562 1.00 7.69 ? 184 GLU A CD 1 ATOM 1310 O OE1 . GLU A 1 184 ? 53.914 60.493 0.424 1.00 11.41 ? 184 GLU A OE1 1 ATOM 1311 O OE2 . GLU A 1 184 ? 54.605 61.411 2.304 1.00 13.81 ? 184 GLU A OE2 1 ATOM 1312 N N . GLY A 1 185 ? 50.574 57.618 3.775 1.00 6.83 ? 185 GLY A N 1 ATOM 1313 C CA . GLY A 1 185 ? 50.380 57.271 5.179 1.00 6.24 ? 185 GLY A CA 1 ATOM 1314 C C . GLY A 1 185 ? 50.915 55.910 5.528 1.00 6.79 ? 185 GLY A C 1 ATOM 1315 O O . GLY A 1 185 ? 51.517 55.745 6.575 1.00 7.32 ? 185 GLY A O 1 ATOM 1316 N N . GLN A 1 186 ? 50.784 54.954 4.636 1.00 7.47 ? 186 GLN A N 1 ATOM 1317 C CA . GLN A 1 186 ? 51.257 53.606 4.974 1.00 7.01 ? 186 GLN A CA 1 ATOM 1318 C C . GLN A 1 186 ? 52.783 53.548 5.009 1.00 7.41 ? 186 GLN A C 1 ATOM 1319 O O . GLN A 1 186 ? 53.353 52.806 5.805 1.00 8.26 ? 186 GLN A O 1 ATOM 1320 C CB . GLN A 1 186 ? 50.653 52.527 4.017 1.00 7.02 ? 186 GLN A CB 1 ATOM 1321 C CG . GLN A 1 186 ? 49.106 52.353 4.252 1.00 7.55 ? 186 GLN A CG 1 ATOM 1322 C CD . GLN A 1 186 ? 48.737 50.923 4.050 1.00 8.27 ? 186 GLN A CD 1 ATOM 1323 O OE1 . GLN A 1 186 ? 49.411 50.237 3.288 1.00 9.82 ? 186 GLN A OE1 1 ATOM 1324 N NE2 . GLN A 1 186 ? 47.678 50.458 4.687 1.00 7.80 ? 186 GLN A NE2 1 ATOM 1325 N N . THR A 1 187 ? 53.471 54.280 4.133 1.00 8.14 ? 187 THR A N 1 ATOM 1326 C CA . THR A 1 187 ? 54.945 54.288 4.153 1.00 8.35 ? 187 THR A CA 1 ATOM 1327 C C . THR A 1 187 ? 55.406 54.899 5.477 1.00 8.82 ? 187 THR A C 1 ATOM 1328 O O . THR A 1 187 ? 56.410 54.390 6.065 1.00 9.91 ? 187 THR A O 1 ATOM 1329 C CB . THR A 1 187 ? 55.460 55.074 2.951 1.00 7.05 ? 187 THR A CB 1 ATOM 1330 O OG1 . THR A 1 187 ? 54.935 54.464 1.755 1.00 9.80 ? 187 THR A OG1 1 ATOM 1331 C CG2 . THR A 1 187 ? 57.031 55.037 2.896 1.00 9.06 ? 187 THR A CG2 1 ATOM 1332 N N . TRP A 1 188 ? 54.707 55.937 5.966 1.00 8.47 ? 188 TRP A N 1 ATOM 1333 C CA . TRP A 1 188 ? 55.060 56.551 7.241 1.00 9.26 ? 188 TRP A CA 1 ATOM 1334 C C . TRP A 1 188 ? 54.838 55.494 8.333 1.00 8.58 ? 188 TRP A C 1 ATOM 1335 O O . TRP A 1 188 ? 55.721 55.245 9.161 1.00 9.08 ? 188 TRP A O 1 ATOM 1336 C CB . TRP A 1 188 ? 54.160 57.750 7.484 1.00 8.52 ? 188 TRP A CB 1 ATOM 1337 C CG . TRP A 1 188 ? 54.626 58.553 8.757 1.00 10.48 ? 188 TRP A CG 1 ATOM 1338 C CD1 . TRP A 1 188 ? 55.560 59.583 8.766 1.00 11.70 ? 188 TRP A CD1 1 ATOM 1339 C CD2 . TRP A 1 188 ? 54.312 58.273 10.127 1.00 9.68 ? 188 TRP A CD2 1 ATOM 1340 N NE1 . TRP A 1 188 ? 55.833 59.936 10.069 1.00 9.91 ? 188 TRP A NE1 1 ATOM 1341 C CE2 . TRP A 1 188 ? 55.093 59.143 10.922 1.00 12.32 ? 188 TRP A CE2 1 ATOM 1342 C CE3 . TRP A 1 188 ? 53.455 57.352 10.758 1.00 11.79 ? 188 TRP A CE3 1 ATOM 1343 C CZ2 . TRP A 1 188 ? 55.041 59.125 12.322 1.00 10.96 ? 188 TRP A CZ2 1 ATOM 1344 C CZ3 . TRP A 1 188 ? 53.406 57.320 12.162 1.00 11.28 ? 188 TRP A CZ3 1 ATOM 1345 C CH2 . TRP A 1 188 ? 54.200 58.212 12.932 1.00 13.79 ? 188 TRP A CH2 1 ATOM 1346 N N . LEU A 1 189 ? 53.720 54.795 8.287 1.00 9.92 ? 189 LEU A N 1 ATOM 1347 C CA . LEU A 1 189 ? 53.447 53.799 9.308 1.00 9.25 ? 189 LEU A CA 1 ATOM 1348 C C . LEU A 1 189 ? 54.470 52.672 9.352 1.00 10.08 ? 189 LEU A C 1 ATOM 1349 O O . LEU A 1 189 ? 54.865 52.260 10.446 1.00 11.35 ? 189 LEU A O 1 ATOM 1350 C CB . LEU A 1 189 ? 51.997 53.187 9.196 1.00 8.61 ? 189 LEU A CB 1 ATOM 1351 C CG . LEU A 1 189 ? 50.847 54.075 9.649 1.00 8.00 ? 189 LEU A CG 1 ATOM 1352 C CD1 . LEU A 1 189 ? 49.504 53.307 9.325 1.00 9.88 ? 189 LEU A CD1 1 ATOM 1353 C CD2 . LEU A 1 189 ? 50.945 54.285 11.176 1.00 6.91 ? 189 LEU A CD2 1 ATOM 1354 N N . LYS A 1 190 ? 54.879 52.139 8.199 1.00 11.46 ? 190 LYS A N 1 ATOM 1355 C CA . LYS A 1 190 ? 55.848 51.049 8.173 1.00 10.20 ? 190 LYS A CA 1 ATOM 1356 C C . LYS A 1 190 ? 57.167 51.550 8.741 1.00 12.11 ? 190 LYS A C 1 ATOM 1357 O O . LYS A 1 190 ? 57.771 50.872 9.616 1.00 13.44 ? 190 LYS A O 1 ATOM 1358 C CB . LYS A 1 190 ? 56.005 50.512 6.740 1.00 12.98 ? 190 LYS A CB 1 ATOM 1359 C CG . LYS A 1 190 ? 57.001 49.298 6.691 1.00 15.12 ? 190 LYS A CG 1 ATOM 1360 C CD . LYS A 1 190 ? 57.110 48.683 5.317 1.00 21.72 ? 190 LYS A CD 1 ATOM 1361 C CE . LYS A 1 190 ? 57.929 47.370 5.343 1.00 24.10 ? 190 LYS A CE 1 ATOM 1362 N NZ . LYS A 1 190 ? 58.361 46.950 3.947 1.00 26.28 ? 190 LYS A NZ 1 ATOM 1363 N N . GLN A 1 191 ? 57.589 52.743 8.353 1.00 10.76 ? 191 GLN A N 1 ATOM 1364 C CA . GLN A 1 191 ? 58.881 53.243 8.813 1.00 14.65 ? 191 GLN A CA 1 ATOM 1365 C C . GLN A 1 191 ? 58.943 53.487 10.302 1.00 15.24 ? 191 GLN A C 1 ATOM 1366 O O . GLN A 1 191 ? 59.917 53.061 11.001 1.00 16.87 ? 191 GLN A O 1 ATOM 1367 C CB . GLN A 1 191 ? 59.178 54.548 8.044 1.00 17.94 ? 191 GLN A CB 1 ATOM 1368 C CG . GLN A 1 191 ? 60.621 55.037 8.062 1.00 24.07 ? 191 GLN A CG 1 ATOM 1369 C CD . GLN A 1 191 ? 60.789 56.346 7.260 1.00 26.44 ? 191 GLN A CD 1 ATOM 1370 O OE1 . GLN A 1 191 ? 59.941 56.706 6.400 1.00 30.41 ? 191 GLN A OE1 1 ATOM 1371 N NE2 . GLN A 1 191 ? 61.889 57.054 7.517 1.00 29.58 ? 191 GLN A NE2 1 ATOM 1372 N N . PHE A 1 192 ? 57.943 54.174 10.819 1.00 14.37 ? 192 PHE A N 1 ATOM 1373 C CA . PHE A 1 192 ? 57.932 54.567 12.225 1.00 13.61 ? 192 PHE A CA 1 ATOM 1374 C C . PHE A 1 192 ? 57.194 53.735 13.265 1.00 14.41 ? 192 PHE A C 1 ATOM 1375 O O . PHE A 1 192 ? 57.568 53.750 14.446 1.00 15.47 ? 192 PHE A O 1 ATOM 1376 C CB . PHE A 1 192 ? 57.465 56.031 12.342 1.00 14.58 ? 192 PHE A CB 1 ATOM 1377 C CG . PHE A 1 192 ? 58.379 56.985 11.644 1.00 12.47 ? 192 PHE A CG 1 ATOM 1378 C CD1 . PHE A 1 192 ? 59.624 57.256 12.192 1.00 14.13 ? 192 PHE A CD1 1 ATOM 1379 C CD2 . PHE A 1 192 ? 58.055 57.546 10.386 1.00 13.14 ? 192 PHE A CD2 1 ATOM 1380 C CE1 . PHE A 1 192 ? 60.534 58.051 11.528 1.00 14.41 ? 192 PHE A CE1 1 ATOM 1381 C CE2 . PHE A 1 192 ? 58.982 58.368 9.691 1.00 13.08 ? 192 PHE A CE2 1 ATOM 1382 C CZ . PHE A 1 192 ? 60.238 58.609 10.294 1.00 15.28 ? 192 PHE A CZ 1 ATOM 1383 N N . MET A 1 193 ? 56.164 52.997 12.850 1.00 11.76 ? 193 MET A N 1 ATOM 1384 C CA . MET A 1 193 ? 55.352 52.184 13.774 1.00 11.60 ? 193 MET A CA 1 ATOM 1385 C C . MET A 1 193 ? 55.475 50.698 13.466 1.00 11.31 ? 193 MET A C 1 ATOM 1386 O O . MET A 1 193 ? 54.970 49.844 14.216 1.00 12.61 ? 193 MET A O 1 ATOM 1387 C CB . MET A 1 193 ? 53.873 52.564 13.655 1.00 10.57 ? 193 MET A CB 1 ATOM 1388 C CG A MET A 1 193 ? 53.460 53.913 14.291 0.50 10.16 ? 193 MET A CG 1 ATOM 1389 C CG B MET A 1 193 ? 53.753 54.184 13.796 0.50 13.94 ? 193 MET A CG 1 ATOM 1390 S SD A MET A 1 193 ? 53.576 53.922 16.126 0.50 11.06 ? 193 MET A SD 1 ATOM 1391 S SD B MET A 1 193 ? 54.707 54.901 15.130 0.50 17.43 ? 193 MET A SD 1 ATOM 1392 C CE A MET A 1 193 ? 55.017 54.934 16.405 0.50 13.27 ? 193 MET A CE 1 ATOM 1393 C CE B MET A 1 193 ? 53.811 54.070 16.435 0.50 13.70 ? 193 MET A CE 1 ATOM 1394 N N . ASN A 1 194 ? 56.156 50.369 12.374 1.00 11.09 ? 194 ASN A N 1 ATOM 1395 C CA . ASN A 1 194 ? 56.321 48.977 11.958 1.00 12.84 ? 194 ASN A CA 1 ATOM 1396 C C . ASN A 1 194 ? 55.013 48.182 11.833 1.00 12.75 ? 194 ASN A C 1 ATOM 1397 O O . ASN A 1 194 ? 54.919 47.012 12.250 1.00 13.93 ? 194 ASN A O 1 ATOM 1398 C CB . ASN A 1 194 ? 57.284 48.266 12.911 1.00 15.90 ? 194 ASN A CB 1 ATOM 1399 C CG . ASN A 1 194 ? 57.771 46.937 12.369 1.00 20.68 ? 194 ASN A CG 1 ATOM 1400 O OD1 . ASN A 1 194 ? 57.892 46.759 11.149 1.00 20.03 ? 194 ASN A OD1 1 ATOM 1401 N ND2 . ASN A 1 194 ? 58.066 46.034 13.295 1.00 26.96 ? 194 ASN A ND2 1 ATOM 1402 N N . VAL A 1 195 ? 53.991 48.811 11.255 1.00 11.06 ? 195 VAL A N 1 ATOM 1403 C CA . VAL A 1 195 ? 52.711 48.125 11.024 1.00 11.65 ? 195 VAL A CA 1 ATOM 1404 C C . VAL A 1 195 ? 52.172 48.562 9.658 1.00 10.17 ? 195 VAL A C 1 ATOM 1405 O O . VAL A 1 195 ? 52.428 49.697 9.222 1.00 9.31 ? 195 VAL A O 1 ATOM 1406 C CB . VAL A 1 195 ? 51.570 48.454 12.114 1.00 11.09 ? 195 VAL A CB 1 ATOM 1407 C CG1 . VAL A 1 195 ? 52.010 48.039 13.536 1.00 15.24 ? 195 VAL A CG1 1 ATOM 1408 C CG2 . VAL A 1 195 ? 51.251 49.915 12.129 1.00 12.24 ? 195 VAL A CG2 1 ATOM 1409 N N . THR A 1 196 ? 51.386 47.687 9.057 1.00 8.79 ? 196 THR A N 1 ATOM 1410 C CA . THR A 1 196 ? 50.689 47.960 7.790 1.00 10.01 ? 196 THR A CA 1 ATOM 1411 C C . THR A 1 196 ? 49.226 47.478 7.959 1.00 8.73 ? 196 THR A C 1 ATOM 1412 O O . THR A 1 196 ? 48.985 46.247 7.994 1.00 9.81 ? 196 THR A O 1 ATOM 1413 C CB . THR A 1 196 ? 51.316 47.214 6.553 1.00 8.57 ? 196 THR A CB 1 ATOM 1414 O OG1 . THR A 1 196 ? 52.680 47.613 6.392 1.00 12.23 ? 196 THR A OG1 1 ATOM 1415 C CG2 . THR A 1 196 ? 50.527 47.506 5.318 1.00 11.57 ? 196 THR A CG2 1 ATOM 1416 N N . PRO A 1 197 ? 48.242 48.410 8.082 1.00 8.76 ? 197 PRO A N 1 ATOM 1417 C CA . PRO A 1 197 ? 46.820 48.033 8.226 1.00 7.82 ? 197 PRO A CA 1 ATOM 1418 C C . PRO A 1 197 ? 46.328 47.187 7.105 1.00 7.84 ? 197 PRO A C 1 ATOM 1419 O O . PRO A 1 197 ? 46.660 47.442 5.934 1.00 8.86 ? 197 PRO A O 1 ATOM 1420 C CB . PRO A 1 197 ? 46.088 49.381 8.224 1.00 8.35 ? 197 PRO A CB 1 ATOM 1421 C CG . PRO A 1 197 ? 47.096 50.375 8.818 1.00 7.31 ? 197 PRO A CG 1 ATOM 1422 C CD . PRO A 1 197 ? 48.421 49.877 8.221 1.00 7.16 ? 197 PRO A CD 1 ATOM 1423 N N . THR A 1 198 ? 45.474 46.197 7.446 1.00 7.25 ? 198 THR A N 1 ATOM 1424 C CA . THR A 1 198 ? 44.868 45.346 6.453 1.00 6.37 ? 198 THR A CA 1 ATOM 1425 C C . THR A 1 198 ? 43.317 45.485 6.528 1.00 6.58 ? 198 THR A C 1 ATOM 1426 O O . THR A 1 198 ? 42.592 44.798 5.804 1.00 6.68 ? 198 THR A O 1 ATOM 1427 C CB . THR A 1 198 ? 45.236 43.891 6.625 1.00 9.30 ? 198 THR A CB 1 ATOM 1428 O OG1 . THR A 1 198 ? 44.735 43.467 7.866 1.00 9.87 ? 198 THR A OG1 1 ATOM 1429 C CG2 . THR A 1 198 ? 46.761 43.681 6.533 1.00 9.65 ? 198 THR A CG2 1 ATOM 1430 N N . ALA A 1 199 ? 42.827 46.356 7.426 1.00 7.67 ? 199 ALA A N 1 ATOM 1431 C CA . ALA A 1 199 ? 41.396 46.670 7.548 1.00 6.79 ? 199 ALA A CA 1 ATOM 1432 C C . ALA A 1 199 ? 41.191 48.183 7.299 1.00 7.28 ? 199 ALA A C 1 ATOM 1433 O O . ALA A 1 199 ? 41.948 48.968 7.826 1.00 8.05 ? 199 ALA A O 1 ATOM 1434 C CB . ALA A 1 199 ? 40.854 46.355 8.940 1.00 6.72 ? 199 ALA A CB 1 ATOM 1435 N N . SER A 1 200 ? 40.205 48.540 6.497 1.00 6.42 ? 200 SER A N 1 ATOM 1436 C CA . SER A 1 200 ? 39.926 49.953 6.176 1.00 6.42 ? 200 SER A CA 1 ATOM 1437 C C . SER A 1 200 ? 38.667 50.431 6.870 1.00 7.31 ? 200 SER A C 1 ATOM 1438 O O . SER A 1 200 ? 37.681 49.661 6.996 1.00 8.04 ? 200 SER A O 1 ATOM 1439 C CB . SER A 1 200 ? 39.737 50.106 4.628 1.00 6.19 ? 200 SER A CB 1 ATOM 1440 O OG . SER A 1 200 ? 39.632 51.478 4.231 1.00 10.12 ? 200 SER A OG 1 ATOM 1441 N N . TRP A 1 201 ? 38.667 51.691 7.271 1.00 5.90 ? 201 TRP A N 1 ATOM 1442 C CA . TRP A 1 201 ? 37.586 52.385 7.999 1.00 6.75 ? 201 TRP A CA 1 ATOM 1443 C C . TRP A 1 201 ? 37.261 53.680 7.217 1.00 7.55 ? 201 TRP A C 1 ATOM 1444 O O . TRP A 1 201 ? 38.081 54.554 7.188 1.00 7.93 ? 201 TRP A O 1 ATOM 1445 C CB . TRP A 1 201 ? 38.110 52.655 9.437 1.00 7.13 ? 201 TRP A CB 1 ATOM 1446 C CG . TRP A 1 201 ? 37.281 53.468 10.318 1.00 8.18 ? 201 TRP A CG 1 ATOM 1447 C CD1 . TRP A 1 201 ? 37.428 54.794 10.569 1.00 7.50 ? 201 TRP A CD1 1 ATOM 1448 C CD2 . TRP A 1 201 ? 36.305 52.984 11.260 1.00 8.57 ? 201 TRP A CD2 1 ATOM 1449 N NE1 . TRP A 1 201 ? 36.627 55.171 11.647 1.00 8.71 ? 201 TRP A NE1 1 ATOM 1450 C CE2 . TRP A 1 201 ? 35.925 54.087 12.078 1.00 8.21 ? 201 TRP A CE2 1 ATOM 1451 C CE3 . TRP A 1 201 ? 35.714 51.731 11.505 1.00 8.24 ? 201 TRP A CE3 1 ATOM 1452 C CZ2 . TRP A 1 201 ? 34.987 53.967 13.136 1.00 8.96 ? 201 TRP A CZ2 1 ATOM 1453 C CZ3 . TRP A 1 201 ? 34.803 51.610 12.547 1.00 8.47 ? 201 TRP A CZ3 1 ATOM 1454 C CH2 . TRP A 1 201 ? 34.438 52.703 13.360 1.00 8.82 ? 201 TRP A CH2 1 ATOM 1455 N N . ALA A 1 202 ? 36.093 53.724 6.574 1.00 7.32 ? 202 ALA A N 1 ATOM 1456 C CA . ALA A 1 202 ? 35.665 54.920 5.806 1.00 7.64 ? 202 ALA A CA 1 ATOM 1457 C C . ALA A 1 202 ? 34.239 55.245 6.281 1.00 8.45 ? 202 ALA A C 1 ATOM 1458 O O . ALA A 1 202 ? 33.229 54.851 5.625 1.00 7.54 ? 202 ALA A O 1 ATOM 1459 C CB . ALA A 1 202 ? 35.735 54.599 4.281 1.00 8.34 ? 202 ALA A CB 1 ATOM 1460 N N . ILE A 1 203 ? 34.113 55.989 7.370 1.00 6.70 ? 203 ILE A N 1 ATOM 1461 C CA . ILE A 1 203 ? 32.800 56.297 7.950 1.00 5.61 ? 203 ILE A CA 1 ATOM 1462 C C . ILE A 1 203 ? 32.163 57.637 7.496 1.00 7.78 ? 203 ILE A C 1 ATOM 1463 O O . ILE A 1 203 ? 30.969 57.813 7.720 1.00 6.76 ? 203 ILE A O 1 ATOM 1464 C CB . ILE A 1 203 ? 32.874 56.392 9.480 1.00 6.75 ? 203 ILE A CB 1 ATOM 1465 C CG1 . ILE A 1 203 ? 34.032 57.296 9.957 1.00 8.31 ? 203 ILE A CG1 1 ATOM 1466 C CG2 . ILE A 1 203 ? 33.139 54.997 10.079 1.00 7.96 ? 203 ILE A CG2 1 ATOM 1467 C CD1 . ILE A 1 203 ? 33.949 57.516 11.523 1.00 6.35 ? 203 ILE A CD1 1 ATOM 1468 N N . ASP A 1 204 ? 32.933 58.534 6.861 1.00 7.34 ? 204 ASP A N 1 ATOM 1469 C CA . ASP A 1 204 ? 32.384 59.829 6.483 1.00 7.85 ? 204 ASP A CA 1 ATOM 1470 C C . ASP A 1 204 ? 32.327 60.245 4.993 1.00 7.52 ? 204 ASP A C 1 ATOM 1471 O O . ASP A 1 204 ? 31.575 61.188 4.679 1.00 9.08 ? 204 ASP A O 1 ATOM 1472 C CB . ASP A 1 204 ? 33.060 60.954 7.325 1.00 7.43 ? 204 ASP A CB 1 ATOM 1473 C CG . ASP A 1 204 ? 32.126 62.130 7.657 1.00 7.14 ? 204 ASP A CG 1 ATOM 1474 O OD1 . ASP A 1 204 ? 30.870 61.941 7.660 1.00 7.19 ? 204 ASP A OD1 1 ATOM 1475 O OD2 . ASP A 1 204 ? 32.680 63.244 8.006 1.00 6.89 ? 204 ASP A OD2 1 ATOM 1476 N N . PRO A 1 205 ? 33.087 59.619 4.049 1.00 6.75 ? 205 PRO A N 1 ATOM 1477 C CA . PRO A 1 205 ? 32.941 60.065 2.666 1.00 7.90 ? 205 PRO A CA 1 ATOM 1478 C C . PRO A 1 205 ? 31.445 60.001 2.270 1.00 7.08 ? 205 PRO A C 1 ATOM 1479 O O . PRO A 1 205 ? 30.694 59.092 2.698 1.00 8.03 ? 205 PRO A O 1 ATOM 1480 C CB . PRO A 1 205 ? 33.808 59.095 1.910 1.00 5.81 ? 205 PRO A CB 1 ATOM 1481 C CG . PRO A 1 205 ? 34.882 58.691 2.930 1.00 11.52 ? 205 PRO A CG 1 ATOM 1482 C CD . PRO A 1 205 ? 34.091 58.550 4.160 1.00 9.68 ? 205 PRO A CD 1 ATOM 1483 N N . PHE A 1 206 ? 31.018 60.896 1.395 1.00 7.99 ? 206 PHE A N 1 ATOM 1484 C CA . PHE A 1 206 ? 29.556 61.033 1.075 1.00 5.74 ? 206 PHE A CA 1 ATOM 1485 C C . PHE A 1 206 ? 29.131 60.175 -0.090 1.00 7.85 ? 206 PHE A C 1 ATOM 1486 O O . PHE A 1 206 ? 28.916 60.645 -1.196 1.00 7.39 ? 206 PHE A O 1 ATOM 1487 C CB . PHE A 1 206 ? 29.238 62.541 0.793 1.00 6.83 ? 206 PHE A CB 1 ATOM 1488 C CG . PHE A 1 206 ? 30.070 63.528 1.635 1.00 6.65 ? 206 PHE A CG 1 ATOM 1489 C CD1 . PHE A 1 206 ? 30.255 63.321 2.994 1.00 4.87 ? 206 PHE A CD1 1 ATOM 1490 C CD2 . PHE A 1 206 ? 30.664 64.652 1.028 1.00 5.40 ? 206 PHE A CD2 1 ATOM 1491 C CE1 . PHE A 1 206 ? 31.027 64.164 3.786 1.00 7.27 ? 206 PHE A CE1 1 ATOM 1492 C CE2 . PHE A 1 206 ? 31.455 65.523 1.830 1.00 6.60 ? 206 PHE A CE2 1 ATOM 1493 C CZ . PHE A 1 206 ? 31.646 65.271 3.199 1.00 4.08 ? 206 PHE A CZ 1 ATOM 1494 N N . GLY A 1 207 ? 29.023 58.874 0.167 1.00 6.81 ? 207 GLY A N 1 ATOM 1495 C CA . GLY A 1 207 ? 28.786 57.887 -0.889 1.00 6.71 ? 207 GLY A CA 1 ATOM 1496 C C . GLY A 1 207 ? 30.139 57.167 -1.031 1.00 5.27 ? 207 GLY A C 1 ATOM 1497 O O . GLY A 1 207 ? 31.222 57.682 -0.666 1.00 8.86 ? 207 GLY A O 1 ATOM 1498 N N . HIS A 1 208 ? 30.092 55.980 -1.601 1.00 5.69 ? 208 HIS A N 1 ATOM 1499 C CA . HIS A 1 208 ? 31.272 55.105 -1.707 1.00 5.37 ? 208 HIS A CA 1 ATOM 1500 C C . HIS A 1 208 ? 31.472 54.499 -3.061 1.00 6.35 ? 208 HIS A C 1 ATOM 1501 O O . HIS A 1 208 ? 30.525 54.097 -3.747 1.00 7.03 ? 208 HIS A O 1 ATOM 1502 C CB . HIS A 1 208 ? 31.165 53.967 -0.626 1.00 6.45 ? 208 HIS A CB 1 ATOM 1503 C CG . HIS A 1 208 ? 31.201 54.441 0.793 1.00 5.34 ? 208 HIS A CG 1 ATOM 1504 N ND1 . HIS A 1 208 ? 32.391 54.731 1.436 1.00 7.42 ? 208 HIS A ND1 1 ATOM 1505 C CD2 . HIS A 1 208 ? 30.216 54.723 1.676 1.00 8.24 ? 208 HIS A CD2 1 ATOM 1506 C CE1 . HIS A 1 208 ? 32.124 55.147 2.660 1.00 6.13 ? 208 HIS A CE1 1 ATOM 1507 N NE2 . HIS A 1 208 ? 30.821 55.159 2.835 1.00 5.65 ? 208 HIS A NE2 1 ATOM 1508 N N . SER A 1 209 ? 32.758 54.372 -3.402 1.00 4.75 ? 209 SER A N 1 ATOM 1509 C CA . SER A 1 209 ? 33.193 53.852 -4.697 1.00 7.08 ? 209 SER A CA 1 ATOM 1510 C C . SER A 1 209 ? 33.901 52.520 -4.659 1.00 5.11 ? 209 SER A C 1 ATOM 1511 O O . SER A 1 209 ? 34.668 52.273 -3.761 1.00 6.05 ? 209 SER A O 1 ATOM 1512 C CB . SER A 1 209 ? 34.222 54.804 -5.328 1.00 6.80 ? 209 SER A CB 1 ATOM 1513 O OG . SER A 1 209 ? 34.675 54.357 -6.598 1.00 7.25 ? 209 SER A OG 1 ATOM 1514 N N . PRO A 1 210 ? 33.646 51.659 -5.652 1.00 5.93 ? 210 PRO A N 1 ATOM 1515 C CA . PRO A 1 210 ? 34.341 50.352 -5.703 1.00 5.86 ? 210 PRO A CA 1 ATOM 1516 C C . PRO A 1 210 ? 35.834 50.539 -6.075 1.00 7.04 ? 210 PRO A C 1 ATOM 1517 O O . PRO A 1 210 ? 36.645 49.572 -6.034 1.00 7.12 ? 210 PRO A O 1 ATOM 1518 C CB . PRO A 1 210 ? 33.618 49.568 -6.812 1.00 6.92 ? 210 PRO A CB 1 ATOM 1519 C CG . PRO A 1 210 ? 33.036 50.652 -7.640 1.00 7.67 ? 210 PRO A CG 1 ATOM 1520 C CD . PRO A 1 210 ? 32.690 51.783 -6.767 1.00 6.65 ? 210 PRO A CD 1 ATOM 1521 N N . THR A 1 211 ? 36.243 51.785 -6.380 1.00 6.17 ? 211 THR A N 1 ATOM 1522 C CA . THR A 1 211 ? 37.678 51.995 -6.619 1.00 8.37 ? 211 THR A CA 1 ATOM 1523 C C . THR A 1 211 ? 38.436 51.749 -5.320 1.00 7.38 ? 211 THR A C 1 ATOM 1524 O O . THR A 1 211 ? 39.580 51.331 -5.370 1.00 7.16 ? 211 THR A O 1 ATOM 1525 C CB . THR A 1 211 ? 37.917 53.433 -7.062 1.00 5.97 ? 211 THR A CB 1 ATOM 1526 O OG1 . THR A 1 211 ? 37.360 53.536 -8.376 1.00 7.63 ? 211 THR A OG1 1 ATOM 1527 C CG2 . THR A 1 211 ? 39.403 53.767 -7.053 1.00 8.50 ? 211 THR A CG2 1 ATOM 1528 N N . MET A 1 212 ? 37.779 51.907 -4.168 1.00 6.33 ? 212 MET A N 1 ATOM 1529 C CA . MET A 1 212 ? 38.481 51.677 -2.913 1.00 7.36 ? 212 MET A CA 1 ATOM 1530 C C . MET A 1 212 ? 38.816 50.183 -2.721 1.00 5.95 ? 212 MET A C 1 ATOM 1531 O O . MET A 1 212 ? 39.975 49.865 -2.516 1.00 7.82 ? 212 MET A O 1 ATOM 1532 C CB . MET A 1 212 ? 37.676 52.265 -1.749 1.00 6.48 ? 212 MET A CB 1 ATOM 1533 C CG . MET A 1 212 ? 37.364 53.738 -1.874 1.00 8.54 ? 212 MET A CG 1 ATOM 1534 S SD . MET A 1 212 ? 38.839 54.752 -2.086 1.00 12.33 ? 212 MET A SD 1 ATOM 1535 C CE . MET A 1 212 ? 39.532 54.880 -0.473 1.00 12.97 ? 212 MET A CE 1 ATOM 1536 N N . PRO A 1 213 ? 37.858 49.237 -2.796 1.00 6.83 ? 213 PRO A N 1 ATOM 1537 C CA . PRO A 1 213 ? 38.281 47.838 -2.635 1.00 5.79 ? 213 PRO A CA 1 ATOM 1538 C C . PRO A 1 213 ? 39.252 47.434 -3.726 1.00 6.74 ? 213 PRO A C 1 ATOM 1539 O O . PRO A 1 213 ? 40.107 46.569 -3.460 1.00 8.02 ? 213 PRO A O 1 ATOM 1540 C CB . PRO A 1 213 ? 36.964 47.043 -2.619 1.00 5.16 ? 213 PRO A CB 1 ATOM 1541 C CG . PRO A 1 213 ? 35.916 47.971 -3.279 1.00 6.09 ? 213 PRO A CG 1 ATOM 1542 C CD . PRO A 1 213 ? 36.381 49.343 -2.787 1.00 7.21 ? 213 PRO A CD 1 ATOM 1543 N N . TYR A 1 214 ? 39.161 48.035 -4.922 1.00 7.59 ? 214 TYR A N 1 ATOM 1544 C CA . TYR A 1 214 ? 40.090 47.711 -6.003 1.00 6.38 ? 214 TYR A CA 1 ATOM 1545 C C . TYR A 1 214 ? 41.518 48.021 -5.531 1.00 8.51 ? 214 TYR A C 1 ATOM 1546 O O . TYR A 1 214 ? 42.369 47.151 -5.603 1.00 7.43 ? 214 TYR A O 1 ATOM 1547 C CB . TYR A 1 214 ? 39.750 48.551 -7.267 1.00 7.09 ? 214 TYR A CB 1 ATOM 1548 C CG . TYR A 1 214 ? 40.731 48.307 -8.440 1.00 10.09 ? 214 TYR A CG 1 ATOM 1549 C CD1 . TYR A 1 214 ? 40.517 47.242 -9.323 1.00 11.45 ? 214 TYR A CD1 1 ATOM 1550 C CD2 . TYR A 1 214 ? 41.824 49.159 -8.658 1.00 9.80 ? 214 TYR A CD2 1 ATOM 1551 C CE1 . TYR A 1 214 ? 41.374 47.042 -10.411 1.00 12.86 ? 214 TYR A CE1 1 ATOM 1552 C CE2 . TYR A 1 214 ? 42.663 48.938 -9.765 1.00 9.63 ? 214 TYR A CE2 1 ATOM 1553 C CZ . TYR A 1 214 ? 42.422 47.906 -10.608 1.00 11.91 ? 214 TYR A CZ 1 ATOM 1554 O OH . TYR A 1 214 ? 43.205 47.833 -11.766 1.00 13.27 ? 214 TYR A OH 1 ATOM 1555 N N . ILE A 1 215 ? 41.759 49.254 -5.088 1.00 6.04 ? 215 ILE A N 1 ATOM 1556 C CA . ILE A 1 215 ? 43.070 49.652 -4.593 1.00 6.47 ? 215 ILE A CA 1 ATOM 1557 C C . ILE A 1 215 ? 43.473 48.927 -3.300 1.00 6.16 ? 215 ILE A C 1 ATOM 1558 O O . ILE A 1 215 ? 44.627 48.436 -3.193 1.00 7.22 ? 215 ILE A O 1 ATOM 1559 C CB . ILE A 1 215 ? 43.135 51.156 -4.378 1.00 4.77 ? 215 ILE A CB 1 ATOM 1560 C CG1 . ILE A 1 215 ? 42.907 51.888 -5.727 1.00 6.40 ? 215 ILE A CG1 1 ATOM 1561 C CG2 . ILE A 1 215 ? 44.498 51.533 -3.691 1.00 7.56 ? 215 ILE A CG2 1 ATOM 1562 C CD1 . ILE A 1 215 ? 42.875 53.376 -5.521 1.00 10.27 ? 215 ILE A CD1 1 ATOM 1563 N N . LEU A 1 216 ? 42.557 48.757 -2.355 1.00 6.31 ? 216 LEU A N 1 ATOM 1564 C CA . LEU A 1 216 ? 42.890 48.114 -1.095 1.00 6.43 ? 216 LEU A CA 1 ATOM 1565 C C . LEU A 1 216 ? 43.268 46.642 -1.258 1.00 6.39 ? 216 LEU A C 1 ATOM 1566 O O . LEU A 1 216 ? 44.246 46.209 -0.684 1.00 6.78 ? 216 LEU A O 1 ATOM 1567 C CB . LEU A 1 216 ? 41.690 48.251 -0.119 1.00 6.90 ? 216 LEU A CB 1 ATOM 1568 C CG . LEU A 1 216 ? 41.332 49.735 0.264 1.00 8.02 ? 216 LEU A CG 1 ATOM 1569 C CD1 . LEU A 1 216 ? 39.973 49.728 1.000 1.00 8.26 ? 216 LEU A CD1 1 ATOM 1570 C CD2 . LEU A 1 216 ? 42.425 50.439 1.173 1.00 10.60 ? 216 LEU A CD2 1 ATOM 1571 N N . GLN A 1 217 ? 42.497 45.915 -2.055 1.00 6.74 ? 217 GLN A N 1 ATOM 1572 C CA . GLN A 1 217 ? 42.762 44.498 -2.219 1.00 7.75 ? 217 GLN A CA 1 ATOM 1573 C C . GLN A 1 217 ? 44.143 44.298 -2.910 1.00 7.29 ? 217 GLN A C 1 ATOM 1574 O O . GLN A 1 217 ? 44.803 43.264 -2.696 1.00 10.41 ? 217 GLN A O 1 ATOM 1575 C CB . GLN A 1 217 ? 41.608 43.879 -2.996 1.00 8.13 ? 217 GLN A CB 1 ATOM 1576 C CG . GLN A 1 217 ? 41.635 42.345 -3.115 1.00 9.27 ? 217 GLN A CG 1 ATOM 1577 C CD . GLN A 1 217 ? 42.512 41.836 -4.193 1.00 14.14 ? 217 GLN A CD 1 ATOM 1578 O OE1 . GLN A 1 217 ? 42.644 42.458 -5.247 1.00 13.93 ? 217 GLN A OE1 1 ATOM 1579 N NE2 . GLN A 1 217 ? 43.088 40.653 -3.968 1.00 14.54 ? 217 GLN A NE2 1 ATOM 1580 N N . LYS A 1 218 ? 44.603 45.252 -3.704 1.00 7.84 ? 218 LYS A N 1 ATOM 1581 C CA . LYS A 1 218 ? 45.927 45.157 -4.352 1.00 7.23 ? 218 LYS A CA 1 ATOM 1582 C C . LYS A 1 218 ? 47.037 45.747 -3.488 1.00 8.25 ? 218 LYS A C 1 ATOM 1583 O O . LYS A 1 218 ? 48.193 45.827 -3.922 1.00 7.77 ? 218 LYS A O 1 ATOM 1584 C CB . LYS A 1 218 ? 45.868 45.874 -5.738 1.00 6.55 ? 218 LYS A CB 1 ATOM 1585 C CG . LYS A 1 218 ? 45.051 45.096 -6.777 1.00 10.15 ? 218 LYS A CG 1 ATOM 1586 C CD . LYS A 1 218 ? 44.753 45.955 -7.972 1.00 10.44 ? 218 LYS A CD 1 ATOM 1587 C CE . LYS A 1 218 ? 44.328 45.198 -9.187 1.00 12.99 ? 218 LYS A CE 1 ATOM 1588 N NZ . LYS A 1 218 ? 43.265 44.217 -8.908 1.00 15.98 ? 218 LYS A NZ 1 ATOM 1589 N N . SER A 1 219 ? 46.692 46.203 -2.276 1.00 7.96 ? 219 SER A N 1 ATOM 1590 C CA . SER A 1 219 ? 47.598 46.805 -1.296 1.00 8.48 ? 219 SER A CA 1 ATOM 1591 C C . SER A 1 219 ? 47.620 45.992 0.029 1.00 6.73 ? 219 SER A C 1 ATOM 1592 O O . SER A 1 219 ? 47.924 46.531 1.096 1.00 7.05 ? 219 SER A O 1 ATOM 1593 C CB . SER A 1 219 ? 47.229 48.285 -1.042 1.00 9.17 ? 219 SER A CB 1 ATOM 1594 O OG . SER A 1 219 ? 47.261 49.028 -2.279 1.00 9.58 ? 219 SER A OG 1 ATOM 1595 N N . GLY A 1 220 ? 47.228 44.704 -0.061 1.00 7.70 ? 220 GLY A N 1 ATOM 1596 C CA . GLY A 1 220 ? 47.305 43.854 1.123 1.00 7.42 ? 220 GLY A CA 1 ATOM 1597 C C . GLY A 1 220 ? 46.086 43.799 2.019 1.00 9.78 ? 220 GLY A C 1 ATOM 1598 O O . GLY A 1 220 ? 46.108 43.036 2.953 1.00 9.02 ? 220 GLY A O 1 ATOM 1599 N N . PHE A 1 221 ? 45.014 44.508 1.693 1.00 8.01 ? 221 PHE A N 1 ATOM 1600 C CA . PHE A 1 221 ? 43.897 44.533 2.604 1.00 8.49 ? 221 PHE A CA 1 ATOM 1601 C C . PHE A 1 221 ? 43.067 43.299 2.548 1.00 8.37 ? 221 PHE A C 1 ATOM 1602 O O . PHE A 1 221 ? 42.983 42.643 1.497 1.00 7.07 ? 221 PHE A O 1 ATOM 1603 C CB . PHE A 1 221 ? 43.025 45.767 2.306 1.00 6.45 ? 221 PHE A CB 1 ATOM 1604 C CG . PHE A 1 221 ? 43.576 47.013 2.888 1.00 7.45 ? 221 PHE A CG 1 ATOM 1605 C CD1 . PHE A 1 221 ? 44.690 47.649 2.314 1.00 5.75 ? 221 PHE A CD1 1 ATOM 1606 C CD2 . PHE A 1 221 ? 42.981 47.590 4.021 1.00 6.38 ? 221 PHE A CD2 1 ATOM 1607 C CE1 . PHE A 1 221 ? 45.185 48.854 2.883 1.00 7.29 ? 221 PHE A CE1 1 ATOM 1608 C CE2 . PHE A 1 221 ? 43.483 48.773 4.572 1.00 7.25 ? 221 PHE A CE2 1 ATOM 1609 C CZ . PHE A 1 221 ? 44.582 49.416 4.015 1.00 5.84 ? 221 PHE A CZ 1 ATOM 1610 N N . LYS A 1 222 ? 42.425 43.018 3.674 1.00 8.92 ? 222 LYS A N 1 ATOM 1611 C CA . LYS A 1 222 ? 41.525 41.855 3.738 1.00 8.95 ? 222 LYS A CA 1 ATOM 1612 C C . LYS A 1 222 ? 40.106 42.230 4.079 1.00 8.29 ? 222 LYS A C 1 ATOM 1613 O O . LYS A 1 222 ? 39.190 41.461 3.872 1.00 7.52 ? 222 LYS A O 1 ATOM 1614 C CB . LYS A 1 222 ? 42.051 40.829 4.751 1.00 12.96 ? 222 LYS A CB 1 ATOM 1615 C CG . LYS A 1 222 ? 43.373 40.279 4.302 1.00 16.75 ? 222 LYS A CG 1 ATOM 1616 C CD . LYS A 1 222 ? 44.054 39.377 5.276 1.00 24.02 ? 222 LYS A CD 1 ATOM 1617 C CE . LYS A 1 222 ? 44.998 38.413 4.469 1.00 25.91 ? 222 LYS A CE 1 ATOM 1618 N NZ . LYS A 1 222 ? 45.626 39.025 3.211 1.00 28.27 ? 222 LYS A NZ 1 ATOM 1619 N N . ASN A 1 223 ? 39.889 43.458 4.576 1.00 6.44 ? 223 ASN A N 1 ATOM 1620 C CA . ASN A 1 223 ? 38.564 43.883 5.007 1.00 6.90 ? 223 ASN A CA 1 ATOM 1621 C C . ASN A 1 223 ? 38.424 45.373 4.941 1.00 7.03 ? 223 ASN A C 1 ATOM 1622 O O . ASN A 1 223 ? 39.400 46.078 5.121 1.00 6.54 ? 223 ASN A O 1 ATOM 1623 C CB . ASN A 1 223 ? 38.357 43.540 6.492 1.00 6.48 ? 223 ASN A CB 1 ATOM 1624 C CG . ASN A 1 223 ? 38.409 42.021 6.758 1.00 8.21 ? 223 ASN A CG 1 ATOM 1625 O OD1 . ASN A 1 223 ? 39.475 41.494 7.206 1.00 11.44 ? 223 ASN A OD1 1 ATOM 1626 N ND2 . ASN A 1 223 ? 37.321 41.329 6.473 1.00 6.86 ? 223 ASN A ND2 1 ATOM 1627 N N . MET A 1 224 ? 37.191 45.835 4.698 1.00 8.17 ? 224 MET A N 1 ATOM 1628 C CA . MET A 1 224 ? 36.891 47.271 4.746 1.00 6.86 ? 224 MET A CA 1 ATOM 1629 C C . MET A 1 224 ? 35.492 47.547 5.307 1.00 6.79 ? 224 MET A C 1 ATOM 1630 O O . MET A 1 224 ? 34.609 46.676 5.273 1.00 7.65 ? 224 MET A O 1 ATOM 1631 C CB . MET A 1 224 ? 37.020 47.896 3.358 1.00 8.27 ? 224 MET A CB 1 ATOM 1632 C CG . MET A 1 224 ? 35.969 47.370 2.355 1.00 8.76 ? 224 MET A CG 1 ATOM 1633 S SD . MET A 1 224 ? 36.154 48.114 0.676 1.00 9.06 ? 224 MET A SD 1 ATOM 1634 C CE . MET A 1 224 ? 35.796 49.794 1.139 1.00 14.33 ? 224 MET A CE 1 ATOM 1635 N N . LEU A 1 225 ? 35.313 48.782 5.774 1.00 5.86 ? 225 LEU A N 1 ATOM 1636 C CA . LEU A 1 225 ? 34.026 49.216 6.376 1.00 6.11 ? 225 LEU A CA 1 ATOM 1637 C C . LEU A 1 225 ? 33.613 50.542 5.758 1.00 7.23 ? 225 LEU A C 1 ATOM 1638 O O . LEU A 1 225 ? 34.460 51.428 5.540 1.00 7.33 ? 225 LEU A O 1 ATOM 1639 C CB . LEU A 1 225 ? 34.176 49.366 7.925 1.00 7.35 ? 225 LEU A CB 1 ATOM 1640 C CG . LEU A 1 225 ? 32.929 49.951 8.628 1.00 8.46 ? 225 LEU A CG 1 ATOM 1641 C CD1 . LEU A 1 225 ? 32.899 49.467 10.095 1.00 8.36 ? 225 LEU A CD1 1 ATOM 1642 C CD2 . LEU A 1 225 ? 33.051 51.512 8.694 1.00 7.81 ? 225 LEU A CD2 1 ATOM 1643 N N . ILE A 1 226 ? 32.314 50.655 5.456 1.00 6.09 ? 226 ILE A N 1 ATOM 1644 C CA . ILE A 1 226 ? 31.703 51.864 4.910 1.00 6.65 ? 226 ILE A CA 1 ATOM 1645 C C . ILE A 1 226 ? 30.458 52.204 5.689 1.00 8.08 ? 226 ILE A C 1 ATOM 1646 O O . ILE A 1 226 ? 29.924 51.336 6.389 1.00 6.80 ? 226 ILE A O 1 ATOM 1647 C CB . ILE A 1 226 ? 31.396 51.750 3.415 1.00 7.60 ? 226 ILE A CB 1 ATOM 1648 C CG1 . ILE A 1 226 ? 30.388 50.623 3.160 1.00 8.37 ? 226 ILE A CG1 1 ATOM 1649 C CG2 . ILE A 1 226 ? 32.701 51.378 2.705 1.00 8.08 ? 226 ILE A CG2 1 ATOM 1650 C CD1 . ILE A 1 226 ? 29.931 50.523 1.726 1.00 7.61 ? 226 ILE A CD1 1 ATOM 1651 N N . GLN A 1 227 ? 30.024 53.463 5.534 1.00 7.11 ? 227 GLN A N 1 ATOM 1652 C CA . GLN A 1 227 ? 28.882 53.972 6.292 1.00 8.04 ? 227 GLN A CA 1 ATOM 1653 C C . GLN A 1 227 ? 27.892 54.810 5.509 1.00 6.88 ? 227 GLN A C 1 ATOM 1654 O O . GLN A 1 227 ? 26.680 54.615 5.658 1.00 6.72 ? 227 GLN A O 1 ATOM 1655 C CB . GLN A 1 227 ? 29.386 54.780 7.522 1.00 8.04 ? 227 GLN A CB 1 ATOM 1656 C CG . GLN A 1 227 ? 28.353 55.854 8.030 1.00 8.64 ? 227 GLN A CG 1 ATOM 1657 C CD . GLN A 1 227 ? 27.047 55.321 8.528 1.00 7.62 ? 227 GLN A CD 1 ATOM 1658 O OE1 . GLN A 1 227 ? 26.925 54.168 8.863 1.00 10.02 ? 227 GLN A OE1 1 ATOM 1659 N NE2 . GLN A 1 227 ? 26.056 56.202 8.569 1.00 8.31 ? 227 GLN A NE2 1 ATOM 1660 N N . ARG A 1 228 ? 28.340 55.754 4.690 1.00 7.71 ? 228 ARG A N 1 ATOM 1661 C CA . ARG A 1 228 ? 27.360 56.636 4.076 1.00 7.93 ? 228 ARG A CA 1 ATOM 1662 C C . ARG A 1 228 ? 26.819 56.118 2.779 1.00 8.15 ? 228 ARG A C 1 ATOM 1663 O O . ARG A 1 228 ? 27.359 56.380 1.698 1.00 8.11 ? 228 ARG A O 1 ATOM 1664 C CB . ARG A 1 228 ? 27.978 58.041 3.885 1.00 7.97 ? 228 ARG A CB 1 ATOM 1665 C CG . ARG A 1 228 ? 28.115 58.823 5.201 1.00 6.95 ? 228 ARG A CG 1 ATOM 1666 C CD . ARG A 1 228 ? 28.389 60.271 4.893 1.00 8.54 ? 228 ARG A CD 1 ATOM 1667 N NE . ARG A 1 228 ? 28.713 61.129 6.030 1.00 7.85 ? 228 ARG A NE 1 ATOM 1668 C CZ . ARG A 1 228 ? 27.806 61.856 6.701 1.00 11.75 ? 228 ARG A CZ 1 ATOM 1669 N NH1 . ARG A 1 228 ? 26.499 61.796 6.376 1.00 10.36 ? 228 ARG A NH1 1 ATOM 1670 N NH2 . ARG A 1 228 ? 28.224 62.651 7.650 1.00 12.19 ? 228 ARG A NH2 1 ATOM 1671 N N . THR A 1 229 ? 25.729 55.356 2.915 1.00 7.78 ? 229 THR A N 1 ATOM 1672 C CA . THR A 1 229 ? 25.053 54.823 1.752 1.00 6.57 ? 229 THR A CA 1 ATOM 1673 C C . THR A 1 229 ? 23.585 55.223 1.881 1.00 6.55 ? 229 THR A C 1 ATOM 1674 O O . THR A 1 229 ? 23.129 55.501 3.015 1.00 8.81 ? 229 THR A O 1 ATOM 1675 C CB . THR A 1 229 ? 25.208 53.267 1.660 1.00 6.92 ? 229 THR A CB 1 ATOM 1676 O OG1 . THR A 1 229 ? 24.522 52.677 2.757 1.00 8.97 ? 229 THR A OG1 1 ATOM 1677 C CG2 . THR A 1 229 ? 26.674 52.870 1.561 1.00 8.78 ? 229 THR A CG2 1 ATOM 1678 N N . HIS A 1 230 ? 22.877 55.296 0.743 1.00 6.86 ? 230 HIS A N 1 ATOM 1679 C CA . HIS A 1 230 ? 21.465 55.708 0.710 1.00 6.81 ? 230 HIS A CA 1 ATOM 1680 C C . HIS A 1 230 ? 20.643 54.983 1.788 1.00 8.21 ? 230 HIS A C 1 ATOM 1681 O O . HIS A 1 230 ? 20.766 53.766 1.925 1.00 7.14 ? 230 HIS A O 1 ATOM 1682 C CB . HIS A 1 230 ? 20.903 55.438 -0.680 1.00 8.81 ? 230 HIS A CB 1 ATOM 1683 C CG . HIS A 1 230 ? 19.623 56.157 -0.976 1.00 10.68 ? 230 HIS A CG 1 ATOM 1684 N ND1 . HIS A 1 230 ? 18.448 55.924 -0.280 1.00 9.60 ? 230 HIS A ND1 1 ATOM 1685 C CD2 . HIS A 1 230 ? 19.338 57.091 -1.909 1.00 10.31 ? 230 HIS A CD2 1 ATOM 1686 C CE1 . HIS A 1 230 ? 17.497 56.700 -0.768 1.00 10.70 ? 230 HIS A CE1 1 ATOM 1687 N NE2 . HIS A 1 230 ? 18.008 57.409 -1.768 1.00 10.52 ? 230 HIS A NE2 1 ATOM 1688 N N . TYR A 1 231 ? 19.824 55.721 2.536 1.00 8.28 ? 231 TYR A N 1 ATOM 1689 C CA . TYR A 1 231 ? 19.027 55.091 3.558 1.00 9.03 ? 231 TYR A CA 1 ATOM 1690 C C . TYR A 1 231 ? 18.141 53.987 2.994 1.00 9.89 ? 231 TYR A C 1 ATOM 1691 O O . TYR A 1 231 ? 17.878 53.022 3.732 1.00 10.40 ? 231 TYR A O 1 ATOM 1692 C CB . TYR A 1 231 ? 18.174 56.120 4.329 1.00 8.23 ? 231 TYR A CB 1 ATOM 1693 C CG . TYR A 1 231 ? 17.168 56.896 3.475 1.00 10.38 ? 231 TYR A CG 1 ATOM 1694 C CD1 . TYR A 1 231 ? 15.863 56.418 3.293 1.00 10.63 ? 231 TYR A CD1 1 ATOM 1695 C CD2 . TYR A 1 231 ? 17.507 58.140 2.873 1.00 9.46 ? 231 TYR A CD2 1 ATOM 1696 C CE1 . TYR A 1 231 ? 14.949 57.155 2.552 1.00 11.25 ? 231 TYR A CE1 1 ATOM 1697 C CE2 . TYR A 1 231 ? 16.605 58.874 2.110 1.00 9.21 ? 231 TYR A CE2 1 ATOM 1698 C CZ . TYR A 1 231 ? 15.299 58.374 1.953 1.00 9.27 ? 231 TYR A CZ 1 ATOM 1699 O OH . TYR A 1 231 ? 14.413 59.147 1.230 1.00 10.99 ? 231 TYR A OH 1 ATOM 1700 N N . SER A 1 232 ? 17.659 54.093 1.769 1.00 9.53 ? 232 SER A N 1 ATOM 1701 C CA . SER A 1 232 ? 16.854 52.993 1.196 1.00 10.98 ? 232 SER A CA 1 ATOM 1702 C C . SER A 1 232 ? 17.713 51.752 0.931 1.00 10.97 ? 232 SER A C 1 ATOM 1703 O O . SER A 1 232 ? 17.227 50.606 0.995 1.00 10.51 ? 232 SER A O 1 ATOM 1704 C CB . SER A 1 232 ? 16.225 53.417 -0.103 1.00 12.26 ? 232 SER A CB 1 ATOM 1705 O OG . SER A 1 232 ? 15.286 54.446 0.107 1.00 13.29 ? 232 SER A OG 1 ATOM 1706 N N . VAL A 1 233 ? 19.001 51.986 0.587 1.00 9.86 ? 233 VAL A N 1 ATOM 1707 C CA . VAL A 1 233 ? 19.898 50.849 0.379 1.00 9.51 ? 233 VAL A CA 1 ATOM 1708 C C . VAL A 1 233 ? 20.185 50.126 1.715 1.00 8.00 ? 233 VAL A C 1 ATOM 1709 O O . VAL A 1 233 ? 20.154 48.869 1.731 1.00 9.39 ? 233 VAL A O 1 ATOM 1710 C CB . VAL A 1 233 ? 21.220 51.285 -0.267 1.00 8.65 ? 233 VAL A CB 1 ATOM 1711 C CG1 . VAL A 1 233 ? 22.193 50.124 -0.314 1.00 10.84 ? 233 VAL A CG1 1 ATOM 1712 C CG2 . VAL A 1 233 ? 20.918 51.768 -1.655 1.00 10.16 ? 233 VAL A CG2 1 ATOM 1713 N N . LYS A 1 234 ? 20.402 50.889 2.782 1.00 10.05 ? 234 LYS A N 1 ATOM 1714 C CA . LYS A 1 234 ? 20.624 50.291 4.118 1.00 8.43 ? 234 LYS A CA 1 ATOM 1715 C C . LYS A 1 234 ? 19.399 49.424 4.509 1.00 9.71 ? 234 LYS A C 1 ATOM 1716 O O . LYS A 1 234 ? 19.565 48.310 4.959 1.00 10.28 ? 234 LYS A O 1 ATOM 1717 C CB . LYS A 1 234 ? 20.875 51.342 5.177 1.00 9.92 ? 234 LYS A CB 1 ATOM 1718 C CG . LYS A 1 234 ? 22.288 51.944 5.167 1.00 10.77 ? 234 LYS A CG 1 ATOM 1719 C CD . LYS A 1 234 ? 22.273 53.263 5.861 1.00 10.72 ? 234 LYS A CD 1 ATOM 1720 C CE . LYS A 1 234 ? 23.652 53.909 5.866 1.00 8.00 ? 234 LYS A CE 1 ATOM 1721 N NZ . LYS A 1 234 ? 24.526 53.356 6.906 1.00 9.06 ? 234 LYS A NZ 1 ATOM 1722 N N . LYS A 1 235 ? 18.192 49.924 4.246 1.00 10.35 ? 235 LYS A N 1 ATOM 1723 C CA . LYS A 1 235 ? 16.973 49.161 4.598 1.00 10.98 ? 235 LYS A CA 1 ATOM 1724 C C . LYS A 1 235 ? 16.859 47.860 3.787 1.00 11.12 ? 235 LYS A C 1 ATOM 1725 O O . LYS A 1 235 ? 16.583 46.762 4.364 1.00 13.01 ? 235 LYS A O 1 ATOM 1726 C CB . LYS A 1 235 ? 15.741 50.048 4.408 1.00 10.17 ? 235 LYS A CB 1 ATOM 1727 C CG . LYS A 1 235 ? 14.453 49.341 4.855 1.00 14.66 ? 235 LYS A CG 1 ATOM 1728 C CD . LYS A 1 235 ? 13.251 50.292 4.666 1.00 15.07 ? 235 LYS A CD 1 ATOM 1729 C CE . LYS A 1 235 ? 11.943 49.651 5.165 1.00 18.82 ? 235 LYS A CE 1 ATOM 1730 N NZ . LYS A 1 235 ? 10.747 50.600 5.230 1.00 22.80 ? 235 LYS A NZ 1 ATOM 1731 N N . GLU A 1 236 ? 17.099 47.942 2.489 1.00 11.14 ? 236 GLU A N 1 ATOM 1732 C CA . GLU A 1 236 ? 16.995 46.800 1.574 1.00 11.44 ? 236 GLU A CA 1 ATOM 1733 C C . GLU A 1 236 ? 18.032 45.723 1.935 1.00 12.59 ? 236 GLU A C 1 ATOM 1734 O O . GLU A 1 236 ? 17.723 44.539 2.110 1.00 10.80 ? 236 GLU A O 1 ATOM 1735 C CB . GLU A 1 236 ? 17.179 47.318 0.120 1.00 16.41 ? 236 GLU A CB 1 ATOM 1736 C CG . GLU A 1 236 ? 16.908 46.276 -0.933 1.00 22.81 ? 236 GLU A CG 1 ATOM 1737 C CD . GLU A 1 236 ? 15.400 45.951 -1.007 1.00 25.30 ? 236 GLU A CD 1 ATOM 1738 O OE1 . GLU A 1 236 ? 14.552 46.803 -0.606 1.00 27.45 ? 236 GLU A OE1 1 ATOM 1739 O OE2 . GLU A 1 236 ? 15.081 44.858 -1.477 1.00 29.19 ? 236 GLU A OE2 1 ATOM 1740 N N . LEU A 1 237 ? 19.287 46.124 2.077 1.00 8.75 ? 237 LEU A N 1 ATOM 1741 C CA . LEU A 1 237 ? 20.291 45.177 2.430 1.00 10.55 ? 237 LEU A CA 1 ATOM 1742 C C . LEU A 1 237 ? 20.107 44.627 3.847 1.00 10.43 ? 237 LEU A C 1 ATOM 1743 O O . LEU A 1 237 ? 20.335 43.403 4.041 1.00 11.55 ? 237 LEU A O 1 ATOM 1744 C CB . LEU A 1 237 ? 21.720 45.775 2.249 1.00 9.25 ? 237 LEU A CB 1 ATOM 1745 C CG . LEU A 1 237 ? 22.054 46.195 0.792 1.00 10.98 ? 237 LEU A CG 1 ATOM 1746 C CD1 . LEU A 1 237 ? 23.537 46.732 0.804 1.00 11.28 ? 237 LEU A CD1 1 ATOM 1747 C CD2 . LEU A 1 237 ? 21.932 45.089 -0.228 1.00 12.23 ? 237 LEU A CD2 1 ATOM 1748 N N . ALA A 1 238 ? 19.671 45.434 4.823 1.00 11.09 ? 238 ALA A N 1 ATOM 1749 C CA . ALA A 1 238 ? 19.465 44.933 6.179 1.00 10.97 ? 238 ALA A CA 1 ATOM 1750 C C . ALA A 1 238 ? 18.413 43.812 6.167 1.00 12.66 ? 238 ALA A C 1 ATOM 1751 O O . ALA A 1 238 ? 18.564 42.808 6.894 1.00 11.81 ? 238 ALA A O 1 ATOM 1752 C CB . ALA A 1 238 ? 18.975 46.061 7.074 1.00 10.56 ? 238 ALA A CB 1 ATOM 1753 N N . GLN A 1 239 ? 17.339 44.025 5.416 1.00 11.91 ? 239 GLN A N 1 ATOM 1754 C CA . GLN A 1 239 ? 16.249 43.046 5.360 1.00 13.74 ? 239 GLN A CA 1 ATOM 1755 C C . GLN A 1 239 ? 16.700 41.680 4.914 1.00 14.15 ? 239 GLN A C 1 ATOM 1756 O O . GLN A 1 239 ? 16.121 40.700 5.368 1.00 16.45 ? 239 GLN A O 1 ATOM 1757 C CB . GLN A 1 239 ? 15.120 43.542 4.474 1.00 13.96 ? 239 GLN A CB 1 ATOM 1758 C CG . GLN A 1 239 ? 14.284 44.589 5.195 1.00 19.26 ? 239 GLN A CG 1 ATOM 1759 C CD . GLN A 1 239 ? 13.243 45.225 4.307 1.00 20.80 ? 239 GLN A CD 1 ATOM 1760 O OE1 . GLN A 1 239 ? 13.412 45.270 3.123 1.00 23.66 ? 239 GLN A OE1 1 ATOM 1761 N NE2 . GLN A 1 239 ? 12.171 45.751 4.899 1.00 23.18 ? 239 GLN A NE2 1 ATOM 1762 N N . GLN A 1 240 ? 17.702 41.607 4.043 1.00 13.48 ? 240 GLN A N 1 ATOM 1763 C CA . GLN A 1 240 ? 18.230 40.364 3.488 1.00 13.05 ? 240 GLN A CA 1 ATOM 1764 C C . GLN A 1 240 ? 19.535 39.946 4.163 1.00 12.24 ? 240 GLN A C 1 ATOM 1765 O O . GLN A 1 240 ? 20.178 38.951 3.803 1.00 12.00 ? 240 GLN A O 1 ATOM 1766 C CB . GLN A 1 240 ? 18.496 40.603 1.997 1.00 15.62 ? 240 GLN A CB 1 ATOM 1767 C CG . GLN A 1 240 ? 17.285 41.125 1.258 1.00 20.29 ? 240 GLN A CG 1 ATOM 1768 C CD . GLN A 1 240 ? 16.143 40.141 1.296 1.00 22.48 ? 240 GLN A CD 1 ATOM 1769 O OE1 . GLN A 1 240 ? 16.359 38.899 1.312 1.00 24.04 ? 240 GLN A OE1 1 ATOM 1770 N NE2 . GLN A 1 240 ? 14.917 40.667 1.297 1.00 22.49 ? 240 GLN A NE2 1 ATOM 1771 N N . ARG A 1 241 ? 19.908 40.669 5.226 1.00 11.83 ? 241 ARG A N 1 ATOM 1772 C CA . ARG A 1 241 ? 21.207 40.448 5.878 1.00 10.21 ? 241 ARG A CA 1 ATOM 1773 C C . ARG A 1 241 ? 22.338 40.408 4.841 1.00 9.96 ? 241 ARG A C 1 ATOM 1774 O O . ARG A 1 241 ? 23.190 39.492 4.813 1.00 10.71 ? 241 ARG A O 1 ATOM 1775 C CB . ARG A 1 241 ? 21.206 39.218 6.817 1.00 10.25 ? 241 ARG A CB 1 ATOM 1776 C CG . ARG A 1 241 ? 20.112 39.304 7.915 1.00 12.39 ? 241 ARG A CG 1 ATOM 1777 C CD . ARG A 1 241 ? 20.164 38.143 8.948 1.00 15.45 ? 241 ARG A CD 1 ATOM 1778 N NE . ARG A 1 241 ? 20.224 36.861 8.281 1.00 20.09 ? 241 ARG A NE 1 ATOM 1779 C CZ . ARG A 1 241 ? 20.680 35.730 8.831 1.00 22.26 ? 241 ARG A CZ 1 ATOM 1780 N NH1 . ARG A 1 241 ? 21.108 35.710 10.103 1.00 21.91 ? 241 ARG A NH1 1 ATOM 1781 N NH2 . ARG A 1 241 ? 20.781 34.635 8.065 1.00 22.84 ? 241 ARG A NH2 1 ATOM 1782 N N . GLN A 1 242 ? 22.355 41.484 4.032 1.00 11.23 ? 242 GLN A N 1 ATOM 1783 C CA . GLN A 1 242 ? 23.388 41.643 2.972 1.00 8.95 ? 242 GLN A CA 1 ATOM 1784 C C . GLN A 1 242 ? 24.258 42.884 3.217 1.00 9.26 ? 242 GLN A C 1 ATOM 1785 O O . GLN A 1 242 ? 24.842 43.416 2.271 1.00 10.21 ? 242 GLN A O 1 ATOM 1786 C CB . GLN A 1 242 ? 22.725 41.699 1.574 1.00 10.67 ? 242 GLN A CB 1 ATOM 1787 C CG . GLN A 1 242 ? 22.055 40.394 1.140 1.00 10.35 ? 242 GLN A CG 1 ATOM 1788 C CD . GLN A 1 242 ? 21.249 40.542 -0.140 1.00 10.06 ? 242 GLN A CD 1 ATOM 1789 O OE1 . GLN A 1 242 ? 20.715 41.566 -0.381 1.00 11.20 ? 242 GLN A OE1 1 ATOM 1790 N NE2 . GLN A 1 242 ? 21.164 39.453 -0.944 1.00 14.06 ? 242 GLN A NE2 1 ATOM 1791 N N . LEU A 1 243 ? 24.414 43.256 4.500 1.00 8.60 ? 243 LEU A N 1 ATOM 1792 C CA . LEU A 1 243 ? 25.212 44.428 4.863 1.00 8.63 ? 243 LEU A CA 1 ATOM 1793 C C . LEU A 1 243 ? 26.652 44.044 4.891 1.00 8.70 ? 243 LEU A C 1 ATOM 1794 O O . LEU A 1 243 ? 27.526 44.929 4.941 1.00 9.53 ? 243 LEU A O 1 ATOM 1795 C CB . LEU A 1 243 ? 24.713 44.920 6.228 1.00 6.67 ? 243 LEU A CB 1 ATOM 1796 C CG . LEU A 1 243 ? 23.319 45.558 6.226 1.00 9.35 ? 243 LEU A CG 1 ATOM 1797 C CD1 . LEU A 1 243 ? 22.908 45.773 7.678 1.00 8.10 ? 243 LEU A CD1 1 ATOM 1798 C CD2 . LEU A 1 243 ? 23.350 46.943 5.492 1.00 10.23 ? 243 LEU A CD2 1 ATOM 1799 N N . GLU A 1 244 ? 26.936 42.750 4.989 1.00 7.65 ? 244 GLU A N 1 ATOM 1800 C CA . GLU A 1 244 ? 28.333 42.270 4.865 1.00 5.86 ? 244 GLU A CA 1 ATOM 1801 C C . GLU A 1 244 ? 28.390 41.468 3.602 1.00 8.43 ? 244 GLU A C 1 ATOM 1802 O O . GLU A 1 244 ? 27.588 40.507 3.410 1.00 8.59 ? 244 GLU A O 1 ATOM 1803 C CB . GLU A 1 244 ? 28.761 41.409 6.064 1.00 9.13 ? 244 GLU A CB 1 ATOM 1804 C CG . GLU A 1 244 ? 29.131 42.341 7.225 1.00 9.87 ? 244 GLU A CG 1 ATOM 1805 C CD . GLU A 1 244 ? 29.427 41.667 8.596 1.00 10.01 ? 244 GLU A CD 1 ATOM 1806 O OE1 . GLU A 1 244 ? 28.842 40.580 8.897 1.00 9.26 ? 244 GLU A OE1 1 ATOM 1807 O OE2 . GLU A 1 244 ? 30.260 42.228 9.380 1.00 8.73 ? 244 GLU A OE2 1 ATOM 1808 N N . PHE A 1 245 ? 29.352 41.816 2.749 1.00 6.75 ? 245 PHE A N 1 ATOM 1809 C CA . PHE A 1 245 ? 29.424 41.185 1.413 1.00 6.71 ? 245 PHE A CA 1 ATOM 1810 C C . PHE A 1 245 ? 30.815 41.153 0.848 1.00 7.17 ? 245 PHE A C 1 ATOM 1811 O O . PHE A 1 245 ? 31.681 41.900 1.338 1.00 8.07 ? 245 PHE A O 1 ATOM 1812 C CB . PHE A 1 245 ? 28.479 41.948 0.411 1.00 7.80 ? 245 PHE A CB 1 ATOM 1813 C CG . PHE A 1 245 ? 28.599 43.436 0.480 1.00 8.92 ? 245 PHE A CG 1 ATOM 1814 C CD1 . PHE A 1 245 ? 29.539 44.113 -0.316 1.00 7.46 ? 245 PHE A CD1 1 ATOM 1815 C CD2 . PHE A 1 245 ? 27.790 44.163 1.355 1.00 10.02 ? 245 PHE A CD2 1 ATOM 1816 C CE1 . PHE A 1 245 ? 29.673 45.535 -0.247 1.00 6.05 ? 245 PHE A CE1 1 ATOM 1817 C CE2 . PHE A 1 245 ? 27.925 45.567 1.422 1.00 9.43 ? 245 PHE A CE2 1 ATOM 1818 C CZ . PHE A 1 245 ? 28.861 46.245 0.621 1.00 7.76 ? 245 PHE A CZ 1 ATOM 1819 N N . LEU A 1 246 ? 31.056 40.333 -0.184 1.00 7.24 ? 246 LEU A N 1 ATOM 1820 C CA . LEU A 1 246 ? 32.372 40.271 -0.832 1.00 6.58 ? 246 LEU A CA 1 ATOM 1821 C C . LEU A 1 246 ? 32.222 41.222 -2.025 1.00 7.55 ? 246 LEU A C 1 ATOM 1822 O O . LEU A 1 246 ? 31.550 40.927 -3.012 1.00 8.11 ? 246 LEU A O 1 ATOM 1823 C CB . LEU A 1 246 ? 32.654 38.809 -1.265 1.00 8.00 ? 246 LEU A CB 1 ATOM 1824 C CG . LEU A 1 246 ? 33.015 37.909 -0.025 1.00 10.67 ? 246 LEU A CG 1 ATOM 1825 C CD1 . LEU A 1 246 ? 32.838 36.429 -0.384 1.00 14.19 ? 246 LEU A CD1 1 ATOM 1826 C CD2 . LEU A 1 246 ? 34.484 38.139 0.337 1.00 13.19 ? 246 LEU A CD2 1 ATOM 1827 N N . TRP A 1 247 ? 32.830 42.410 -1.890 1.00 7.88 ? 247 TRP A N 1 ATOM 1828 C CA . TRP A 1 247 ? 32.660 43.399 -2.945 1.00 7.78 ? 247 TRP A CA 1 ATOM 1829 C C . TRP A 1 247 ? 33.696 43.209 -4.055 1.00 6.85 ? 247 TRP A C 1 ATOM 1830 O O . TRP A 1 247 ? 34.881 43.414 -3.842 1.00 7.76 ? 247 TRP A O 1 ATOM 1831 C CB . TRP A 1 247 ? 32.773 44.781 -2.296 1.00 8.34 ? 247 TRP A CB 1 ATOM 1832 C CG . TRP A 1 247 ? 32.317 46.012 -3.113 1.00 7.23 ? 247 TRP A CG 1 ATOM 1833 C CD1 . TRP A 1 247 ? 31.745 46.040 -4.361 1.00 8.14 ? 247 TRP A CD1 1 ATOM 1834 C CD2 . TRP A 1 247 ? 32.347 47.359 -2.664 1.00 7.11 ? 247 TRP A CD2 1 ATOM 1835 N NE1 . TRP A 1 247 ? 31.406 47.340 -4.708 1.00 8.28 ? 247 TRP A NE1 1 ATOM 1836 C CE2 . TRP A 1 247 ? 31.762 48.158 -3.675 1.00 6.82 ? 247 TRP A CE2 1 ATOM 1837 C CE3 . TRP A 1 247 ? 32.804 47.981 -1.481 1.00 6.81 ? 247 TRP A CE3 1 ATOM 1838 C CZ2 . TRP A 1 247 ? 31.611 49.542 -3.545 1.00 8.93 ? 247 TRP A CZ2 1 ATOM 1839 C CZ3 . TRP A 1 247 ? 32.652 49.385 -1.354 1.00 5.75 ? 247 TRP A CZ3 1 ATOM 1840 C CH2 . TRP A 1 247 ? 32.057 50.153 -2.388 1.00 5.66 ? 247 TRP A CH2 1 ATOM 1841 N N . ARG A 1 248 ? 33.205 42.856 -5.248 1.00 7.13 ? 248 ARG A N 1 ATOM 1842 C CA . ARG A 1 248 ? 34.085 42.666 -6.423 1.00 8.62 ? 248 ARG A CA 1 ATOM 1843 C C . ARG A 1 248 ? 33.776 43.750 -7.489 1.00 6.23 ? 248 ARG A C 1 ATOM 1844 O O . ARG A 1 248 ? 32.732 44.435 -7.427 1.00 7.16 ? 248 ARG A O 1 ATOM 1845 C CB . ARG A 1 248 ? 33.856 41.319 -7.112 1.00 8.46 ? 248 ARG A CB 1 ATOM 1846 C CG . ARG A 1 248 ? 32.473 41.153 -7.742 1.00 9.52 ? 248 ARG A CG 1 ATOM 1847 C CD . ARG A 1 248 ? 32.419 39.924 -8.648 1.00 14.72 ? 248 ARG A CD 1 ATOM 1848 N NE . ARG A 1 248 ? 32.508 38.734 -7.796 1.00 12.06 ? 248 ARG A NE 1 ATOM 1849 C CZ . ARG A 1 248 ? 32.421 37.475 -8.250 1.00 15.69 ? 248 ARG A CZ 1 ATOM 1850 N NH1 . ARG A 1 248 ? 32.264 37.265 -9.566 1.00 15.87 ? 248 ARG A NH1 1 ATOM 1851 N NH2 . ARG A 1 248 ? 32.378 36.454 -7.365 1.00 15.76 ? 248 ARG A NH2 1 ATOM 1852 N N . GLN A 1 249 ? 34.724 43.934 -8.400 1.00 8.08 ? 249 GLN A N 1 ATOM 1853 C CA . GLN A 1 249 ? 34.539 44.918 -9.444 1.00 8.57 ? 249 GLN A CA 1 ATOM 1854 C C . GLN A 1 249 ? 33.448 44.497 -10.406 1.00 9.29 ? 249 GLN A C 1 ATOM 1855 O O . GLN A 1 249 ? 33.196 43.324 -10.594 1.00 8.95 ? 249 GLN A O 1 ATOM 1856 C CB . GLN A 1 249 ? 35.880 45.059 -10.154 1.00 8.26 ? 249 GLN A CB 1 ATOM 1857 C CG . GLN A 1 249 ? 36.989 45.592 -9.213 1.00 9.27 ? 249 GLN A CG 1 ATOM 1858 C CD . GLN A 1 249 ? 36.557 46.932 -8.544 1.00 9.87 ? 249 GLN A CD 1 ATOM 1859 O OE1 . GLN A 1 249 ? 36.247 47.917 -9.253 1.00 9.31 ? 249 GLN A OE1 1 ATOM 1860 N NE2 . GLN A 1 249 ? 36.574 46.986 -7.214 1.00 7.76 ? 249 GLN A NE2 1 ATOM 1861 N N . ILE A 1 250 ? 32.834 45.457 -11.061 1.00 8.60 ? 250 ILE A N 1 ATOM 1862 C CA . ILE A 1 250 ? 31.702 45.134 -11.918 1.00 10.07 ? 250 ILE A CA 1 ATOM 1863 C C . ILE A 1 250 ? 31.990 44.250 -13.099 1.00 11.64 ? 250 ILE A C 1 ATOM 1864 O O . ILE A 1 250 ? 31.067 43.606 -13.607 1.00 9.57 ? 250 ILE A O 1 ATOM 1865 C CB . ILE A 1 250 ? 30.965 46.451 -12.410 1.00 9.56 ? 250 ILE A CB 1 ATOM 1866 C CG1 . ILE A 1 250 ? 31.929 47.362 -13.197 1.00 11.07 ? 250 ILE A CG1 1 ATOM 1867 C CG2 . ILE A 1 250 ? 30.368 47.236 -11.254 1.00 8.75 ? 250 ILE A CG2 1 ATOM 1868 C CD1 . ILE A 1 250 ? 31.287 48.765 -13.634 1.00 12.30 ? 250 ILE A CD1 1 ATOM 1869 N N . TRP A 1 251 ? 33.237 44.237 -13.535 1.00 11.29 ? 251 TRP A N 1 ATOM 1870 C CA . TRP A 1 251 ? 33.601 43.401 -14.673 1.00 12.95 ? 251 TRP A CA 1 ATOM 1871 C C . TRP A 1 251 ? 34.291 42.102 -14.263 1.00 14.87 ? 251 TRP A C 1 ATOM 1872 O O . TRP A 1 251 ? 34.745 41.366 -15.154 1.00 16.49 ? 251 TRP A O 1 ATOM 1873 C CB . TRP A 1 251 ? 34.607 44.092 -15.574 1.00 13.72 ? 251 TRP A CB 1 ATOM 1874 C CG . TRP A 1 251 ? 35.872 44.220 -14.885 1.00 16.77 ? 251 TRP A CG 1 ATOM 1875 C CD1 . TRP A 1 251 ? 36.868 43.251 -14.719 1.00 17.93 ? 251 TRP A CD1 1 ATOM 1876 C CD2 . TRP A 1 251 ? 36.286 45.329 -14.162 1.00 14.61 ? 251 TRP A CD2 1 ATOM 1877 N NE1 . TRP A 1 251 ? 37.865 43.728 -13.926 1.00 16.41 ? 251 TRP A NE1 1 ATOM 1878 C CE2 . TRP A 1 251 ? 37.535 45.013 -13.563 1.00 15.95 ? 251 TRP A CE2 1 ATOM 1879 C CE3 . TRP A 1 251 ? 35.727 46.580 -13.947 1.00 14.87 ? 251 TRP A CE3 1 ATOM 1880 C CZ2 . TRP A 1 251 ? 38.226 45.907 -12.770 1.00 16.85 ? 251 TRP A CZ2 1 ATOM 1881 C CZ3 . TRP A 1 251 ? 36.413 47.470 -13.154 1.00 15.51 ? 251 TRP A CZ3 1 ATOM 1882 C CH2 . TRP A 1 251 ? 37.647 47.128 -12.578 1.00 17.72 ? 251 TRP A CH2 1 ATOM 1883 N N . ASP A 1 252 ? 34.406 41.836 -12.966 1.00 13.78 ? 252 ASP A N 1 ATOM 1884 C CA . ASP A 1 252 ? 35.149 40.679 -12.491 1.00 14.74 ? 252 ASP A CA 1 ATOM 1885 C C . ASP A 1 252 ? 34.308 39.426 -12.387 1.00 15.23 ? 252 ASP A C 1 ATOM 1886 O O . ASP A 1 252 ? 33.522 39.192 -11.483 1.00 14.60 ? 252 ASP A O 1 ATOM 1887 C CB . ASP A 1 252 ? 35.754 41.042 -11.152 1.00 14.61 ? 252 ASP A CB 1 ATOM 1888 C CG . ASP A 1 252 ? 36.514 39.918 -10.510 1.00 17.25 ? 252 ASP A CG 1 ATOM 1889 O OD1 . ASP A 1 252 ? 36.788 38.885 -11.164 1.00 18.77 ? 252 ASP A OD1 1 ATOM 1890 O OD2 . ASP A 1 252 ? 36.848 40.059 -9.312 1.00 15.11 ? 252 ASP A OD2 1 ATOM 1891 N N . ASN A 1 253 ? 34.511 38.580 -13.367 1.00 17.04 ? 253 ASN A N 1 ATOM 1892 C CA . ASN A 1 253 ? 33.730 37.386 -13.451 1.00 16.19 ? 253 ASN A CA 1 ATOM 1893 C C . ASN A 1 253 ? 34.095 36.280 -12.458 1.00 17.01 ? 253 ASN A C 1 ATOM 1894 O O . ASN A 1 253 ? 33.208 35.556 -12.003 1.00 17.61 ? 253 ASN A O 1 ATOM 1895 C CB . ASN A 1 253 ? 33.880 36.836 -14.866 1.00 18.99 ? 253 ASN A CB 1 ATOM 1896 C CG . ASN A 1 253 ? 32.988 35.683 -15.099 1.00 21.36 ? 253 ASN A CG 1 ATOM 1897 O OD1 . ASN A 1 253 ? 31.777 35.786 -14.912 1.00 22.96 ? 253 ASN A OD1 1 ATOM 1898 N ND2 . ASN A 1 253 ? 33.567 34.558 -15.509 1.00 23.15 ? 253 ASN A ND2 1 ATOM 1899 N N . LYS A 1 254 ? 35.392 36.183 -12.177 1.00 18.72 ? 254 LYS A N 1 ATOM 1900 C CA . LYS A 1 254 ? 35.958 35.177 -11.304 1.00 20.92 ? 254 LYS A CA 1 ATOM 1901 C C . LYS A 1 254 ? 35.836 35.516 -9.826 1.00 19.88 ? 254 LYS A C 1 ATOM 1902 O O . LYS A 1 254 ? 35.563 34.651 -8.983 1.00 21.49 ? 254 LYS A O 1 ATOM 1903 C CB . LYS A 1 254 ? 37.435 34.991 -11.669 1.00 23.89 ? 254 LYS A CB 1 ATOM 1904 C CG . LYS A 1 254 ? 38.050 33.709 -11.157 1.00 29.17 ? 254 LYS A CG 1 ATOM 1905 C CD . LYS A 1 254 ? 39.367 33.429 -11.906 1.00 32.56 ? 254 LYS A CD 1 ATOM 1906 C CE . LYS A 1 254 ? 40.126 32.242 -11.278 1.00 34.35 ? 254 LYS A CE 1 ATOM 1907 N NZ . LYS A 1 254 ? 40.362 32.456 -9.820 1.00 35.41 ? 254 LYS A NZ 1 ATOM 1908 N N . GLY A 1 255 ? 36.004 36.802 -9.535 1.00 18.78 ? 255 GLY A N 1 ATOM 1909 C CA . GLY A 1 255 ? 35.958 37.263 -8.161 1.00 17.19 ? 255 GLY A CA 1 ATOM 1910 C C . GLY A 1 255 ? 37.316 37.497 -7.515 1.00 16.62 ? 255 GLY A C 1 ATOM 1911 O O . GLY A 1 255 ? 37.344 37.676 -6.294 1.00 16.96 ? 255 GLY A O 1 ATOM 1912 N N . ASP A 1 256 ? 38.421 37.554 -8.269 1.00 15.70 ? 256 ASP A N 1 ATOM 1913 C CA . ASP A 1 256 ? 39.734 37.755 -7.631 1.00 18.35 ? 256 ASP A CA 1 ATOM 1914 C C . ASP A 1 256 ? 39.939 39.140 -7.044 1.00 15.77 ? 256 ASP A C 1 ATOM 1915 O O . ASP A 1 256 ? 40.821 39.351 -6.255 1.00 14.69 ? 256 ASP A O 1 ATOM 1916 C CB . ASP A 1 256 ? 40.908 37.575 -8.593 1.00 24.53 ? 256 ASP A CB 1 ATOM 1917 C CG . ASP A 1 256 ? 41.065 36.168 -9.102 1.00 29.04 ? 256 ASP A CG 1 ATOM 1918 O OD1 . ASP A 1 256 ? 40.651 35.205 -8.396 1.00 31.85 ? 256 ASP A OD1 1 ATOM 1919 O OD2 . ASP A 1 256 ? 41.635 36.062 -10.216 1.00 32.22 ? 256 ASP A OD2 1 ATOM 1920 N N . THR A 1 257 ? 39.121 40.100 -7.427 1.00 11.88 ? 257 THR A N 1 ATOM 1921 C CA . THR A 1 257 ? 39.234 41.437 -6.868 1.00 11.83 ? 257 THR A CA 1 ATOM 1922 C C . THR A 1 257 ? 38.396 41.594 -5.591 1.00 12.24 ? 257 THR A C 1 ATOM 1923 O O . THR A 1 257 ? 38.467 42.642 -4.956 1.00 11.70 ? 257 THR A O 1 ATOM 1924 C CB . THR A 1 257 ? 38.696 42.510 -7.838 1.00 11.38 ? 257 THR A CB 1 ATOM 1925 O OG1 . THR A 1 257 ? 37.282 42.310 -8.054 1.00 10.82 ? 257 THR A OG1 1 ATOM 1926 C CG2 . THR A 1 257 ? 39.446 42.414 -9.188 1.00 13.66 ? 257 THR A CG2 1 ATOM 1927 N N . ALA A 1 258 ? 37.651 40.553 -5.206 1.00 12.86 ? 258 ALA A N 1 ATOM 1928 C CA . ALA A 1 258 ? 36.743 40.690 -4.066 1.00 10.68 ? 258 ALA A CA 1 ATOM 1929 C C . ALA A 1 258 ? 37.372 41.075 -2.723 1.00 10.16 ? 258 ALA A C 1 ATOM 1930 O O . ALA A 1 258 ? 38.495 40.605 -2.357 1.00 9.14 ? 258 ALA A O 1 ATOM 1931 C CB . ALA A 1 258 ? 35.935 39.450 -3.901 1.00 11.79 ? 258 ALA A CB 1 ATOM 1932 N N . LEU A 1 259 ? 36.698 41.968 -2.002 1.00 7.88 ? 259 LEU A N 1 ATOM 1933 C CA . LEU A 1 259 ? 37.171 42.371 -0.654 1.00 7.45 ? 259 LEU A CA 1 ATOM 1934 C C . LEU A 1 259 ? 35.997 42.376 0.284 1.00 8.99 ? 259 LEU A C 1 ATOM 1935 O O . LEU A 1 259 ? 34.957 42.939 -0.041 1.00 7.05 ? 259 LEU A O 1 ATOM 1936 C CB . LEU A 1 259 ? 37.844 43.766 -0.730 1.00 9.86 ? 259 LEU A CB 1 ATOM 1937 C CG . LEU A 1 259 ? 38.553 44.154 0.558 1.00 8.24 ? 259 LEU A CG 1 ATOM 1938 C CD1 . LEU A 1 259 ? 39.849 43.254 0.729 1.00 9.59 ? 259 LEU A CD1 1 ATOM 1939 C CD2 . LEU A 1 259 ? 39.023 45.610 0.448 1.00 11.34 ? 259 LEU A CD2 1 ATOM 1940 N N . PHE A 1 260 ? 36.150 41.630 1.389 1.00 7.93 ? 260 PHE A N 1 ATOM 1941 C CA . PHE A 1 260 ? 35.096 41.607 2.416 1.00 7.92 ? 260 PHE A CA 1 ATOM 1942 C C . PHE A 1 260 ? 34.784 43.028 2.886 1.00 7.44 ? 260 PHE A C 1 ATOM 1943 O O . PHE A 1 260 ? 35.696 43.744 3.313 1.00 8.58 ? 260 PHE A O 1 ATOM 1944 C CB . PHE A 1 260 ? 35.503 40.769 3.640 1.00 8.24 ? 260 PHE A CB 1 ATOM 1945 C CG . PHE A 1 260 ? 34.368 40.585 4.631 1.00 7.66 ? 260 PHE A CG 1 ATOM 1946 C CD1 . PHE A 1 260 ? 33.405 39.599 4.409 1.00 8.68 ? 260 PHE A CD1 1 ATOM 1947 C CD2 . PHE A 1 260 ? 34.280 41.366 5.767 1.00 8.48 ? 260 PHE A CD2 1 ATOM 1948 C CE1 . PHE A 1 260 ? 32.370 39.430 5.374 1.00 11.26 ? 260 PHE A CE1 1 ATOM 1949 C CE2 . PHE A 1 260 ? 33.267 41.203 6.695 1.00 8.31 ? 260 PHE A CE2 1 ATOM 1950 C CZ . PHE A 1 260 ? 32.319 40.215 6.479 1.00 10.02 ? 260 PHE A CZ 1 ATOM 1951 N N . THR A 1 261 ? 33.501 43.375 2.883 1.00 5.17 ? 261 THR A N 1 ATOM 1952 C CA . THR A 1 261 ? 33.066 44.726 3.219 1.00 6.60 ? 261 THR A CA 1 ATOM 1953 C C . THR A 1 261 ? 31.942 44.711 4.234 1.00 6.40 ? 261 THR A C 1 ATOM 1954 O O . THR A 1 261 ? 30.950 43.966 4.114 1.00 8.32 ? 261 THR A O 1 ATOM 1955 C CB . THR A 1 261 ? 32.537 45.436 1.949 1.00 8.18 ? 261 THR A CB 1 ATOM 1956 O OG1 . THR A 1 261 ? 33.588 45.543 0.977 1.00 7.64 ? 261 THR A OG1 1 ATOM 1957 C CG2 . THR A 1 261 ? 32.098 46.866 2.228 1.00 6.92 ? 261 THR A CG2 1 ATOM 1958 N N . HIS A 1 262 ? 32.061 45.588 5.230 1.00 7.70 ? 262 HIS A N 1 ATOM 1959 C CA . HIS A 1 262 ? 30.983 45.715 6.249 1.00 6.57 ? 262 HIS A CA 1 ATOM 1960 C C . HIS A 1 262 ? 30.307 47.105 6.106 1.00 6.60 ? 262 HIS A C 1 ATOM 1961 O O . HIS A 1 262 ? 30.999 48.142 6.205 1.00 8.53 ? 262 HIS A O 1 ATOM 1962 C CB . HIS A 1 262 ? 31.597 45.618 7.630 1.00 7.30 ? 262 HIS A CB 1 ATOM 1963 C CG . HIS A 1 262 ? 30.646 45.956 8.742 1.00 6.07 ? 262 HIS A CG 1 ATOM 1964 N ND1 . HIS A 1 262 ? 30.024 44.991 9.520 1.00 7.35 ? 262 HIS A ND1 1 ATOM 1965 C CD2 . HIS A 1 262 ? 30.197 47.163 9.179 1.00 6.14 ? 262 HIS A CD2 1 ATOM 1966 C CE1 . HIS A 1 262 ? 29.222 45.610 10.380 1.00 6.33 ? 262 HIS A CE1 1 ATOM 1967 N NE2 . HIS A 1 262 ? 29.300 46.924 10.201 1.00 6.85 ? 262 HIS A NE2 1 ATOM 1968 N N . MET A 1 263 ? 29.029 47.142 5.756 1.00 6.02 ? 263 MET A N 1 ATOM 1969 C CA . MET A 1 263 ? 28.328 48.387 5.686 1.00 7.62 ? 263 MET A CA 1 ATOM 1970 C C . MET A 1 263 ? 27.563 48.595 7.037 1.00 6.94 ? 263 MET A C 1 ATOM 1971 O O . MET A 1 263 ? 26.810 47.714 7.445 1.00 9.69 ? 263 MET A O 1 ATOM 1972 C CB . MET A 1 263 ? 27.352 48.372 4.496 1.00 8.25 ? 263 MET A CB 1 ATOM 1973 C CG . MET A 1 263 ? 26.464 49.629 4.476 1.00 7.04 ? 263 MET A CG 1 ATOM 1974 S SD . MET A 1 263 ? 25.134 49.545 3.199 1.00 8.97 ? 263 MET A SD 1 ATOM 1975 C CE . MET A 1 263 ? 26.050 49.217 1.630 1.00 8.47 ? 263 MET A CE 1 ATOM 1976 N N . MET A 1 264 ? 27.782 49.727 7.690 1.00 7.57 ? 264 MET A N 1 ATOM 1977 C CA . MET A 1 264 ? 27.076 50.034 8.933 1.00 7.69 ? 264 MET A CA 1 ATOM 1978 C C . MET A 1 264 ? 25.602 50.243 8.518 1.00 6.87 ? 264 MET A C 1 ATOM 1979 O O . MET A 1 264 ? 25.300 50.706 7.414 1.00 7.42 ? 264 MET A O 1 ATOM 1980 C CB . MET A 1 264 ? 27.710 51.269 9.581 1.00 5.78 ? 264 MET A CB 1 ATOM 1981 C CG A MET A 1 264 ? 29.193 51.032 9.838 0.50 6.10 ? 264 MET A CG 1 ATOM 1982 C CG B MET A 1 264 ? 29.189 50.791 10.083 0.50 11.80 ? 264 MET A CG 1 ATOM 1983 S SD A MET A 1 264 ? 30.078 52.469 10.590 0.50 7.22 ? 264 MET A SD 1 ATOM 1984 S SD B MET A 1 264 ? 29.738 51.472 11.662 0.50 15.43 ? 264 MET A SD 1 ATOM 1985 C CE A MET A 1 264 ? 28.866 52.969 11.869 0.50 7.41 ? 264 MET A CE 1 ATOM 1986 C CE B MET A 1 264 ? 29.390 53.124 11.412 0.50 14.13 ? 264 MET A CE 1 ATOM 1987 N N . PRO A 1 265 ? 24.644 49.866 9.393 1.00 8.09 ? 265 PRO A N 1 ATOM 1988 C CA . PRO A 1 265 ? 23.211 49.976 9.091 1.00 9.90 ? 265 PRO A CA 1 ATOM 1989 C C . PRO A 1 265 ? 22.404 51.180 9.290 1.00 8.07 ? 265 PRO A C 1 ATOM 1990 O O . PRO A 1 265 ? 21.323 51.255 8.690 1.00 9.31 ? 265 PRO A O 1 ATOM 1991 C CB . PRO A 1 265 ? 22.616 48.863 9.941 1.00 10.42 ? 265 PRO A CB 1 ATOM 1992 C CG . PRO A 1 265 ? 23.462 48.853 11.180 1.00 10.73 ? 265 PRO A CG 1 ATOM 1993 C CD . PRO A 1 265 ? 24.902 49.341 10.737 1.00 7.95 ? 265 PRO A CD 1 ATOM 1994 N N . PHE A 1 266 ? 22.919 52.121 10.085 1.00 9.09 ? 266 PHE A N 1 ATOM 1995 C CA . PHE A 1 266 ? 22.143 53.274 10.502 1.00 7.53 ? 266 PHE A CA 1 ATOM 1996 C C . PHE A 1 266 ? 22.496 54.640 9.951 1.00 9.31 ? 266 PHE A C 1 ATOM 1997 O O . PHE A 1 266 ? 23.369 54.755 9.098 1.00 10.01 ? 266 PHE A O 1 ATOM 1998 C CB . PHE A 1 266 ? 22.103 53.267 12.015 1.00 7.42 ? 266 PHE A CB 1 ATOM 1999 C CG . PHE A 1 266 ? 21.522 51.972 12.616 1.00 10.86 ? 266 PHE A CG 1 ATOM 2000 C CD1 . PHE A 1 266 ? 20.399 51.372 12.053 1.00 8.84 ? 266 PHE A CD1 1 ATOM 2001 C CD2 . PHE A 1 266 ? 22.160 51.345 13.716 1.00 7.69 ? 266 PHE A CD2 1 ATOM 2002 C CE1 . PHE A 1 266 ? 19.883 50.139 12.562 1.00 8.14 ? 266 PHE A CE1 1 ATOM 2003 C CE2 . PHE A 1 266 ? 21.646 50.108 14.214 1.00 9.48 ? 266 PHE A CE2 1 ATOM 2004 C CZ . PHE A 1 266 ? 20.505 49.522 13.625 1.00 9.45 ? 266 PHE A CZ 1 ATOM 2005 N N . TYR A 1 267 ? 21.788 55.653 10.371 1.00 9.22 ? 267 TYR A N 1 ATOM 2006 C CA . TYR A 1 267 ? 21.910 56.972 9.770 1.00 9.08 ? 267 TYR A CA 1 ATOM 2007 C C . TYR A 1 267 ? 23.236 57.685 9.978 1.00 9.30 ? 267 TYR A C 1 ATOM 2008 O O . TYR A 1 267 ? 23.644 58.490 9.136 1.00 9.12 ? 267 TYR A O 1 ATOM 2009 C CB . TYR A 1 267 ? 20.678 57.799 10.233 1.00 10.81 ? 267 TYR A CB 1 ATOM 2010 C CG . TYR A 1 267 ? 20.782 59.292 10.125 1.00 11.13 ? 267 TYR A CG 1 ATOM 2011 C CD1 . TYR A 1 267 ? 20.408 59.978 8.967 1.00 11.41 ? 267 TYR A CD1 1 ATOM 2012 C CD2 . TYR A 1 267 ? 21.245 60.029 11.222 1.00 10.20 ? 267 TYR A CD2 1 ATOM 2013 C CE1 . TYR A 1 267 ? 20.487 61.381 8.938 1.00 12.98 ? 267 TYR A CE1 1 ATOM 2014 C CE2 . TYR A 1 267 ? 21.323 61.442 11.199 1.00 12.14 ? 267 TYR A CE2 1 ATOM 2015 C CZ . TYR A 1 267 ? 20.943 62.086 10.064 1.00 13.25 ? 267 TYR A CZ 1 ATOM 2016 O OH . TYR A 1 267 ? 21.009 63.483 10.060 1.00 18.03 ? 267 TYR A OH 1 ATOM 2017 N N . SER A 1 268 ? 23.916 57.395 11.061 1.00 8.14 ? 268 SER A N 1 ATOM 2018 C CA . SER A 1 268 ? 25.195 58.062 11.362 1.00 9.39 ? 268 SER A CA 1 ATOM 2019 C C . SER A 1 268 ? 26.152 57.099 12.033 1.00 9.18 ? 268 SER A C 1 ATOM 2020 O O . SER A 1 268 ? 25.736 56.034 12.443 1.00 9.46 ? 268 SER A O 1 ATOM 2021 C CB . SER A 1 268 ? 24.901 59.220 12.342 1.00 10.13 ? 268 SER A CB 1 ATOM 2022 O OG . SER A 1 268 ? 26.105 59.920 12.697 1.00 12.61 ? 268 SER A OG 1 ATOM 2023 N N . TYR A 1 269 ? 27.420 57.496 12.172 1.00 8.82 ? 269 TYR A N 1 ATOM 2024 C CA . TYR A 1 269 ? 28.394 56.704 12.932 1.00 9.12 ? 269 TYR A CA 1 ATOM 2025 C C . TYR A 1 269 ? 28.508 57.209 14.360 1.00 8.99 ? 269 TYR A C 1 ATOM 2026 O O . TYR A 1 269 ? 29.356 56.719 15.147 1.00 10.02 ? 269 TYR A O 1 ATOM 2027 C CB . TYR A 1 269 ? 29.798 56.768 12.278 1.00 9.66 ? 269 TYR A CB 1 ATOM 2028 C CG . TYR A 1 269 ? 30.298 58.174 11.988 1.00 10.39 ? 269 TYR A CG 1 ATOM 2029 C CD1 . TYR A 1 269 ? 30.745 58.977 13.030 1.00 8.85 ? 269 TYR A CD1 1 ATOM 2030 C CD2 . TYR A 1 269 ? 30.297 58.698 10.683 1.00 8.53 ? 269 TYR A CD2 1 ATOM 2031 C CE1 . TYR A 1 269 ? 31.190 60.309 12.827 1.00 8.69 ? 269 TYR A CE1 1 ATOM 2032 C CE2 . TYR A 1 269 ? 30.746 60.011 10.455 1.00 9.58 ? 269 TYR A CE2 1 ATOM 2033 C CZ . TYR A 1 269 ? 31.179 60.789 11.517 1.00 10.06 ? 269 TYR A CZ 1 ATOM 2034 O OH . TYR A 1 269 ? 31.613 62.071 11.190 1.00 11.34 ? 269 TYR A OH 1 ATOM 2035 N N . ASP A 1 270 ? 27.720 58.247 14.707 1.00 9.28 ? 270 ASP A N 1 ATOM 2036 C CA . ASP A 1 270 ? 27.804 58.720 16.074 1.00 9.28 ? 270 ASP A CA 1 ATOM 2037 C C . ASP A 1 270 ? 27.224 57.694 17.076 1.00 10.23 ? 270 ASP A C 1 ATOM 2038 O O . ASP A 1 270 ? 26.646 56.667 16.681 1.00 9.46 ? 270 ASP A O 1 ATOM 2039 C CB . ASP A 1 270 ? 27.148 60.126 16.230 1.00 11.17 ? 270 ASP A CB 1 ATOM 2040 C CG . ASP A 1 270 ? 25.625 60.149 16.002 1.00 14.46 ? 270 ASP A CG 1 ATOM 2041 O OD1 . ASP A 1 270 ? 24.941 59.110 15.813 1.00 14.30 ? 270 ASP A OD1 1 ATOM 2042 O OD2 . ASP A 1 270 ? 25.115 61.304 16.025 1.00 14.23 ? 270 ASP A OD2 1 ATOM 2043 N N . ILE A 1 271 ? 27.400 57.932 18.382 1.00 10.58 ? 271 ILE A N 1 ATOM 2044 C CA . ILE A 1 271 ? 26.923 56.945 19.372 1.00 11.29 ? 271 ILE A CA 1 ATOM 2045 C C . ILE A 1 271 ? 25.413 56.679 19.310 1.00 11.78 ? 271 ILE A C 1 ATOM 2046 O O . ILE A 1 271 ? 25.008 55.501 19.368 1.00 11.11 ? 271 ILE A O 1 ATOM 2047 C CB . ILE A 1 271 ? 27.467 57.305 20.729 1.00 11.02 ? 271 ILE A CB 1 ATOM 2048 C CG1 . ILE A 1 271 ? 28.980 57.117 20.634 1.00 10.56 ? 271 ILE A CG1 1 ATOM 2049 C CG2 . ILE A 1 271 ? 26.963 56.320 21.846 1.00 8.84 ? 271 ILE A CG2 1 ATOM 2050 C CD1 . ILE A 1 271 ? 29.718 57.628 21.818 1.00 10.12 ? 271 ILE A CD1 1 ATOM 2051 N N . PRO A 1 272 ? 24.577 57.729 19.200 1.00 11.26 ? 272 PRO A N 1 ATOM 2052 C CA . PRO A 1 272 ? 23.125 57.508 19.106 1.00 11.43 ? 272 PRO A CA 1 ATOM 2053 C C . PRO A 1 272 ? 22.742 56.548 17.959 1.00 12.50 ? 272 PRO A C 1 ATOM 2054 O O . PRO A 1 272 ? 21.694 55.910 18.032 1.00 13.44 ? 272 PRO A O 1 ATOM 2055 C CB . PRO A 1 272 ? 22.547 58.907 18.888 1.00 10.03 ? 272 PRO A CB 1 ATOM 2056 C CG . PRO A 1 272 ? 23.475 59.740 19.718 1.00 11.96 ? 272 PRO A CG 1 ATOM 2057 C CD . PRO A 1 272 ? 24.879 59.148 19.403 1.00 10.99 ? 272 PRO A CD 1 ATOM 2058 N N . HIS A 1 273 ? 23.578 56.419 16.910 1.00 11.51 ? 273 HIS A N 1 ATOM 2059 C CA . HIS A 1 273 ? 23.202 55.576 15.792 1.00 10.37 ? 273 HIS A CA 1 ATOM 2060 C C . HIS A 1 273 ? 24.126 54.358 15.606 1.00 10.92 ? 273 HIS A C 1 ATOM 2061 O O . HIS A 1 273 ? 24.211 53.809 14.496 1.00 10.39 ? 273 HIS A O 1 ATOM 2062 C CB . HIS A 1 273 ? 23.125 56.403 14.489 1.00 10.17 ? 273 HIS A CB 1 ATOM 2063 C CG . HIS A 1 273 ? 22.060 57.456 14.538 1.00 11.80 ? 273 HIS A CG 1 ATOM 2064 N ND1 . HIS A 1 273 ? 22.288 58.724 15.034 1.00 11.94 ? 273 HIS A ND1 1 ATOM 2065 C CD2 . HIS A 1 273 ? 20.740 57.402 14.225 1.00 11.25 ? 273 HIS A CD2 1 ATOM 2066 C CE1 . HIS A 1 273 ? 21.143 59.402 15.030 1.00 13.35 ? 273 HIS A CE1 1 ATOM 2067 N NE2 . HIS A 1 273 ? 20.196 58.623 14.551 1.00 8.74 ? 273 HIS A NE2 1 ATOM 2068 N N . THR A 1 274 ? 24.829 53.990 16.663 1.00 10.34 ? 274 THR A N 1 ATOM 2069 C CA . THR A 1 274 ? 25.717 52.859 16.539 1.00 10.63 ? 274 THR A CA 1 ATOM 2070 C C . THR A 1 274 ? 25.454 51.770 17.563 1.00 11.45 ? 274 THR A C 1 ATOM 2071 O O . THR A 1 274 ? 25.931 50.658 17.405 1.00 10.43 ? 274 THR A O 1 ATOM 2072 C CB . THR A 1 274 ? 27.238 53.272 16.548 1.00 10.51 ? 274 THR A CB 1 ATOM 2073 O OG1 . THR A 1 274 ? 27.492 54.229 17.582 1.00 9.34 ? 274 THR A OG1 1 ATOM 2074 C CG2 . THR A 1 274 ? 27.637 53.785 15.164 1.00 9.40 ? 274 THR A CG2 1 ATOM 2075 N N . CYS A 1 275 ? 24.699 52.023 18.621 1.00 10.84 ? 275 CYS A N 1 ATOM 2076 C CA . CYS A 1 275 ? 24.446 50.922 19.541 1.00 12.05 ? 275 CYS A CA 1 ATOM 2077 C C . CYS A 1 275 ? 23.265 50.000 19.177 1.00 11.01 ? 275 CYS A C 1 ATOM 2078 O O . CYS A 1 275 ? 23.217 48.885 19.673 1.00 12.47 ? 275 CYS A O 1 ATOM 2079 C CB . CYS A 1 275 ? 24.191 51.427 20.978 1.00 11.96 ? 275 CYS A CB 1 ATOM 2080 S SG . CYS A 1 275 ? 22.417 51.592 21.512 1.00 14.20 ? 275 CYS A SG 1 ATOM 2081 N N . GLY A 1 276 ? 22.374 50.456 18.298 1.00 11.59 ? 276 GLY A N 1 ATOM 2082 C CA . GLY A 1 276 ? 21.156 49.731 17.953 1.00 10.54 ? 276 GLY A CA 1 ATOM 2083 C C . GLY A 1 276 ? 20.276 50.674 17.156 1.00 11.56 ? 276 GLY A C 1 ATOM 2084 O O . GLY A 1 276 ? 20.617 51.839 16.916 1.00 10.84 ? 276 GLY A O 1 ATOM 2085 N N . PRO A 1 277 ? 19.069 50.237 16.827 1.00 11.39 ? 277 PRO A N 1 ATOM 2086 C CA . PRO A 1 277 ? 18.102 51.009 16.029 1.00 10.63 ? 277 PRO A CA 1 ATOM 2087 C C . PRO A 1 277 ? 17.410 52.223 16.668 1.00 10.67 ? 277 PRO A C 1 ATOM 2088 O O . PRO A 1 277 ? 16.855 53.013 15.936 1.00 11.91 ? 277 PRO A O 1 ATOM 2089 C CB . PRO A 1 277 ? 17.054 49.923 15.621 1.00 11.54 ? 277 PRO A CB 1 ATOM 2090 C CG . PRO A 1 277 ? 17.089 49.002 16.927 1.00 10.96 ? 277 PRO A CG 1 ATOM 2091 C CD . PRO A 1 277 ? 18.540 48.891 17.175 1.00 11.55 ? 277 PRO A CD 1 ATOM 2092 N N . ASP A 1 278 ? 17.431 52.336 17.993 1.00 13.08 ? 278 ASP A N 1 ATOM 2093 C CA . ASP A 1 278 ? 16.725 53.450 18.687 1.00 12.69 ? 278 ASP A CA 1 ATOM 2094 C C . ASP A 1 278 ? 17.711 54.489 19.250 1.00 13.35 ? 278 ASP A C 1 ATOM 2095 O O . ASP A 1 278 ? 18.293 54.288 20.326 1.00 12.11 ? 278 ASP A O 1 ATOM 2096 C CB . ASP A 1 278 ? 15.851 52.910 19.824 1.00 13.20 ? 278 ASP A CB 1 ATOM 2097 C CG . ASP A 1 278 ? 14.929 53.991 20.382 1.00 13.32 ? 278 ASP A CG 1 ATOM 2098 O OD1 . ASP A 1 278 ? 15.116 55.187 20.034 1.00 15.07 ? 278 ASP A OD1 1 ATOM 2099 O OD2 . ASP A 1 278 ? 13.996 53.630 21.121 1.00 15.38 ? 278 ASP A OD2 1 ATOM 2100 N N . PRO A 1 279 ? 17.813 55.636 18.558 1.00 12.83 ? 279 PRO A N 1 ATOM 2101 C CA . PRO A 1 279 ? 18.764 56.638 19.038 1.00 14.33 ? 279 PRO A CA 1 ATOM 2102 C C . PRO A 1 279 ? 18.391 57.228 20.378 1.00 13.95 ? 279 PRO A C 1 ATOM 2103 O O . PRO A 1 279 ? 19.263 57.693 21.126 1.00 15.03 ? 279 PRO A O 1 ATOM 2104 C CB . PRO A 1 279 ? 18.842 57.651 17.863 1.00 12.86 ? 279 PRO A CB 1 ATOM 2105 C CG . PRO A 1 279 ? 17.471 57.580 17.254 1.00 12.46 ? 279 PRO A CG 1 ATOM 2106 C CD . PRO A 1 279 ? 17.092 56.080 17.336 1.00 13.97 ? 279 PRO A CD 1 ATOM 2107 N N . LYS A 1 280 ? 17.104 57.186 20.734 1.00 14.54 ? 280 LYS A N 1 ATOM 2108 C CA . LYS A 1 280 ? 16.737 57.724 22.050 1.00 14.73 ? 280 LYS A CA 1 ATOM 2109 C C . LYS A 1 280 ? 17.339 56.888 23.151 1.00 15.07 ? 280 LYS A C 1 ATOM 2110 O O . LYS A 1 280 ? 17.630 57.408 24.222 1.00 14.87 ? 280 LYS A O 1 ATOM 2111 C CB . LYS A 1 280 ? 15.210 57.785 22.218 1.00 16.45 ? 280 LYS A CB 1 ATOM 2112 C CG . LYS A 1 280 ? 14.748 58.181 23.619 1.00 19.98 ? 280 LYS A CG 1 ATOM 2113 C CD . LYS A 1 280 ? 13.248 58.462 23.662 1.00 23.84 ? 280 LYS A CD 1 ATOM 2114 C CE . LYS A 1 280 ? 12.781 58.468 25.114 1.00 25.61 ? 280 LYS A CE 1 ATOM 2115 N NZ . LYS A 1 280 ? 13.228 57.189 25.788 1.00 30.26 ? 280 LYS A NZ 1 ATOM 2116 N N . VAL A 1 281 ? 17.509 55.574 22.935 1.00 12.89 ? 281 VAL A N 1 ATOM 2117 C CA . VAL A 1 281 ? 18.146 54.713 23.912 1.00 14.38 ? 281 VAL A CA 1 ATOM 2118 C C . VAL A 1 281 ? 19.684 54.826 23.775 1.00 13.26 ? 281 VAL A C 1 ATOM 2119 O O . VAL A 1 281 ? 20.376 54.979 24.802 1.00 14.61 ? 281 VAL A O 1 ATOM 2120 C CB . VAL A 1 281 ? 17.685 53.224 23.699 1.00 14.66 ? 281 VAL A CB 1 ATOM 2121 C CG1 . VAL A 1 281 ? 18.388 52.275 24.649 1.00 16.24 ? 281 VAL A CG1 1 ATOM 2122 C CG2 . VAL A 1 281 ? 16.135 53.169 23.833 1.00 17.08 ? 281 VAL A CG2 1 ATOM 2123 N N . CYS A 1 282 ? 20.211 54.765 22.537 1.00 13.45 ? 282 CYS A N 1 ATOM 2124 C CA . CYS A 1 282 ? 21.689 54.807 22.378 1.00 11.92 ? 282 CYS A CA 1 ATOM 2125 C C . CYS A 1 282 ? 22.336 56.062 22.862 1.00 12.47 ? 282 CYS A C 1 ATOM 2126 O O . CYS A 1 282 ? 23.454 55.996 23.436 1.00 12.16 ? 282 CYS A O 1 ATOM 2127 C CB . CYS A 1 282 ? 22.124 54.556 20.929 1.00 12.11 ? 282 CYS A CB 1 ATOM 2128 S SG . CYS A 1 282 ? 21.591 52.936 20.254 1.00 13.88 ? 282 CYS A SG 1 ATOM 2129 N N . CYS A 1 283 ? 21.625 57.188 22.692 1.00 12.51 ? 283 CYS A N 1 ATOM 2130 C CA . CYS A 1 283 ? 22.150 58.454 23.163 1.00 13.57 ? 283 CYS A CA 1 ATOM 2131 C C . CYS A 1 283 ? 22.417 58.362 24.662 1.00 12.96 ? 283 CYS A C 1 ATOM 2132 O O . CYS A 1 283 ? 23.332 59.003 25.141 1.00 13.07 ? 283 CYS A O 1 ATOM 2133 C CB . CYS A 1 283 ? 21.165 59.602 22.841 1.00 12.52 ? 283 CYS A CB 1 ATOM 2134 S SG . CYS A 1 283 ? 22.032 61.209 22.990 1.00 17.20 ? 283 CYS A SG 1 ATOM 2135 N N . GLN A 1 284 ? 21.640 57.566 25.406 1.00 13.65 ? 284 GLN A N 1 ATOM 2136 C CA . GLN A 1 284 ? 21.881 57.414 26.828 1.00 13.09 ? 284 GLN A CA 1 ATOM 2137 C C . GLN A 1 284 ? 23.161 56.662 27.189 1.00 13.42 ? 284 GLN A C 1 ATOM 2138 O O . GLN A 1 284 ? 23.529 56.575 28.371 1.00 13.91 ? 284 GLN A O 1 ATOM 2139 C CB . GLN A 1 284 ? 20.662 56.758 27.501 1.00 15.15 ? 284 GLN A CB 1 ATOM 2140 C CG . GLN A 1 284 ? 19.360 57.490 27.249 1.00 15.06 ? 284 GLN A CG 1 ATOM 2141 C CD . GLN A 1 284 ? 18.172 56.739 27.800 1.00 17.80 ? 284 GLN A CD 1 ATOM 2142 O OE1 . GLN A 1 284 ? 18.171 56.338 28.956 1.00 17.63 ? 284 GLN A OE1 1 ATOM 2143 N NE2 . GLN A 1 284 ? 17.153 56.533 26.966 1.00 16.95 ? 284 GLN A NE2 1 ATOM 2144 N N . PHE A 1 285 ? 23.866 56.161 26.154 1.00 12.03 ? 285 PHE A N 1 ATOM 2145 C CA . PHE A 1 285 ? 25.111 55.456 26.360 1.00 12.34 ? 285 PHE A CA 1 ATOM 2146 C C . PHE A 1 285 ? 26.314 56.171 25.756 1.00 11.85 ? 285 PHE A C 1 ATOM 2147 O O . PHE A 1 285 ? 27.391 55.597 25.604 1.00 13.32 ? 285 PHE A O 1 ATOM 2148 C CB . PHE A 1 285 ? 24.957 53.994 25.915 1.00 12.57 ? 285 PHE A CB 1 ATOM 2149 C CG . PHE A 1 285 ? 23.931 53.233 26.771 1.00 12.77 ? 285 PHE A CG 1 ATOM 2150 C CD1 . PHE A 1 285 ? 24.308 52.647 27.980 1.00 10.52 ? 285 PHE A CD1 1 ATOM 2151 C CD2 . PHE A 1 285 ? 22.576 53.217 26.391 1.00 11.62 ? 285 PHE A CD2 1 ATOM 2152 C CE1 . PHE A 1 285 ? 23.347 52.062 28.825 1.00 13.83 ? 285 PHE A CE1 1 ATOM 2153 C CE2 . PHE A 1 285 ? 21.615 52.633 27.211 1.00 15.31 ? 285 PHE A CE2 1 ATOM 2154 C CZ . PHE A 1 285 ? 22.002 52.065 28.432 1.00 12.61 ? 285 PHE A CZ 1 ATOM 2155 N N . ASP A 1 286 ? 26.116 57.467 25.527 1.00 12.35 ? 286 ASP A N 1 ATOM 2156 C CA . ASP A 1 286 ? 27.212 58.344 25.134 1.00 11.17 ? 286 ASP A CA 1 ATOM 2157 C C . ASP A 1 286 ? 27.441 59.164 26.434 1.00 10.33 ? 286 ASP A C 1 ATOM 2158 O O . ASP A 1 286 ? 26.756 60.167 26.687 1.00 12.34 ? 286 ASP A O 1 ATOM 2159 C CB . ASP A 1 286 ? 26.777 59.232 23.991 1.00 11.00 ? 286 ASP A CB 1 ATOM 2160 C CG . ASP A 1 286 ? 27.901 60.141 23.485 1.00 10.03 ? 286 ASP A CG 1 ATOM 2161 O OD1 . ASP A 1 286 ? 28.943 60.219 24.206 1.00 12.26 ? 286 ASP A OD1 1 ATOM 2162 O OD2 . ASP A 1 286 ? 27.701 60.761 22.435 1.00 13.19 ? 286 ASP A OD2 1 ATOM 2163 N N . PHE A 1 287 ? 28.419 58.756 27.231 1.00 11.22 ? 287 PHE A N 1 ATOM 2164 C CA . PHE A 1 287 ? 28.618 59.396 28.508 1.00 11.14 ? 287 PHE A CA 1 ATOM 2165 C C . PHE A 1 287 ? 29.208 60.778 28.511 1.00 12.89 ? 287 PHE A C 1 ATOM 2166 O O . PHE A 1 287 ? 29.331 61.366 29.598 1.00 14.34 ? 287 PHE A O 1 ATOM 2167 C CB . PHE A 1 287 ? 29.349 58.428 29.457 1.00 12.66 ? 287 PHE A CB 1 ATOM 2168 C CG . PHE A 1 287 ? 28.546 57.172 29.728 1.00 14.53 ? 287 PHE A CG 1 ATOM 2169 C CD1 . PHE A 1 287 ? 27.553 57.177 30.729 1.00 14.52 ? 287 PHE A CD1 1 ATOM 2170 C CD2 . PHE A 1 287 ? 28.698 56.031 28.953 1.00 13.96 ? 287 PHE A CD2 1 ATOM 2171 C CE1 . PHE A 1 287 ? 26.727 56.062 30.938 1.00 15.74 ? 287 PHE A CE1 1 ATOM 2172 C CE2 . PHE A 1 287 ? 27.863 54.910 29.178 1.00 14.75 ? 287 PHE A CE2 1 ATOM 2173 C CZ . PHE A 1 287 ? 26.873 54.940 30.179 1.00 15.56 ? 287 PHE A CZ 1 ATOM 2174 N N . LYS A 1 288 ? 29.491 61.298 27.312 1.00 13.19 ? 288 LYS A N 1 ATOM 2175 C CA . LYS A 1 288 ? 29.991 62.670 27.185 1.00 14.00 ? 288 LYS A CA 1 ATOM 2176 C C . LYS A 1 288 ? 28.759 63.611 27.130 1.00 13.99 ? 288 LYS A C 1 ATOM 2177 O O . LYS A 1 288 ? 28.893 64.808 27.127 1.00 15.12 ? 288 LYS A O 1 ATOM 2178 C CB . LYS A 1 288 ? 30.839 62.847 25.898 1.00 12.15 ? 288 LYS A CB 1 ATOM 2179 C CG . LYS A 1 288 ? 31.739 64.065 25.948 1.00 12.90 ? 288 LYS A CG 1 ATOM 2180 C CD . LYS A 1 288 ? 32.558 64.260 24.705 1.00 10.71 ? 288 LYS A CD 1 ATOM 2181 C CE . LYS A 1 288 ? 33.456 65.471 24.965 1.00 13.83 ? 288 LYS A CE 1 ATOM 2182 N NZ . LYS A 1 288 ? 34.424 65.736 23.824 1.00 14.61 ? 288 LYS A NZ 1 ATOM 2183 N N . ARG A 1 289 ? 27.545 63.068 27.106 1.00 16.02 ? 289 ARG A N 1 ATOM 2184 C CA . ARG A 1 289 ? 26.381 63.923 27.006 1.00 16.97 ? 289 ARG A CA 1 ATOM 2185 C C . ARG A 1 289 ? 25.581 64.223 28.284 1.00 17.37 ? 289 ARG A C 1 ATOM 2186 O O . ARG A 1 289 ? 24.398 64.513 28.147 1.00 17.40 ? 289 ARG A O 1 ATOM 2187 C CB . ARG A 1 289 ? 25.418 63.361 25.952 1.00 14.43 ? 289 ARG A CB 1 ATOM 2188 C CG . ARG A 1 289 ? 26.014 63.267 24.539 1.00 15.02 ? 289 ARG A CG 1 ATOM 2189 C CD . ARG A 1 289 ? 25.004 62.716 23.583 1.00 13.19 ? 289 ARG A CD 1 ATOM 2190 N NE . ARG A 1 289 ? 25.535 62.446 22.252 1.00 12.32 ? 289 ARG A NE 1 ATOM 2191 C CZ . ARG A 1 289 ? 25.125 63.026 21.143 1.00 12.53 ? 289 ARG A CZ 1 ATOM 2192 N NH1 . ARG A 1 289 ? 24.179 63.963 21.152 1.00 13.59 ? 289 ARG A NH1 1 ATOM 2193 N NH2 . ARG A 1 289 ? 25.577 62.615 19.989 1.00 12.02 ? 289 ARG A NH2 1 ATOM 2194 N N . MET A 1 290 ? 26.183 64.194 29.480 1.00 21.31 ? 290 MET A N 1 ATOM 2195 C CA . MET A 1 290 ? 25.438 64.469 30.727 1.00 24.23 ? 290 MET A CA 1 ATOM 2196 C C . MET A 1 290 ? 25.462 65.911 31.212 1.00 25.52 ? 290 MET A C 1 ATOM 2197 O O . MET A 1 290 ? 24.797 66.240 32.231 1.00 28.19 ? 290 MET A O 1 ATOM 2198 C CB . MET A 1 290 ? 25.898 63.568 31.868 1.00 24.24 ? 290 MET A CB 1 ATOM 2199 C CG . MET A 1 290 ? 25.656 62.091 31.572 1.00 25.88 ? 290 MET A CG 1 ATOM 2200 S SD . MET A 1 290 ? 26.214 60.950 32.872 1.00 26.72 ? 290 MET A SD 1 ATOM 2201 C CE . MET A 1 290 ? 27.916 61.079 32.752 1.00 24.49 ? 290 MET A CE 1 ATOM 2202 N N . GLY A 1 291 ? 26.212 66.783 30.530 1.00 24.60 ? 291 GLY A N 1 ATOM 2203 C CA . GLY A 1 291 ? 26.207 68.175 30.954 1.00 24.07 ? 291 GLY A CA 1 ATOM 2204 C C . GLY A 1 291 ? 27.463 69.040 30.957 1.00 22.99 ? 291 GLY A C 1 ATOM 2205 O O . GLY A 1 291 ? 27.509 70.083 30.282 1.00 23.10 ? 291 GLY A O 1 ATOM 2206 N N . SER A 1 292 ? 28.452 68.609 31.730 1.00 21.87 ? 292 SER A N 1 ATOM 2207 C CA . SER A 1 292 ? 29.705 69.321 31.875 1.00 19.78 ? 292 SER A CA 1 ATOM 2208 C C . SER A 1 292 ? 30.536 69.518 30.581 1.00 19.69 ? 292 SER A C 1 ATOM 2209 O O . SER A 1 292 ? 31.458 70.347 30.529 1.00 17.54 ? 292 SER A O 1 ATOM 2210 C CB . SER A 1 292 ? 30.534 68.611 32.921 1.00 20.12 ? 292 SER A CB 1 ATOM 2211 O OG . SER A 1 292 ? 30.931 67.355 32.396 1.00 19.18 ? 292 SER A OG 1 ATOM 2212 N N . PHE A 1 293 ? 30.220 68.749 29.537 1.00 17.49 ? 293 PHE A N 1 ATOM 2213 C CA . PHE A 1 293 ? 30.890 68.844 28.242 1.00 17.46 ? 293 PHE A CA 1 ATOM 2214 C C . PHE A 1 293 ? 30.102 69.646 27.233 1.00 16.89 ? 293 PHE A C 1 ATOM 2215 O O . PHE A 1 293 ? 30.514 69.756 26.072 1.00 18.40 ? 293 PHE A O 1 ATOM 2216 C CB . PHE A 1 293 ? 31.105 67.426 27.655 1.00 17.00 ? 293 PHE A CB 1 ATOM 2217 C CG . PHE A 1 293 ? 32.033 66.595 28.443 1.00 14.94 ? 293 PHE A CG 1 ATOM 2218 C CD1 . PHE A 1 293 ? 33.406 66.763 28.322 1.00 17.10 ? 293 PHE A CD1 1 ATOM 2219 C CD2 . PHE A 1 293 ? 31.531 65.653 29.356 1.00 15.50 ? 293 PHE A CD2 1 ATOM 2220 C CE1 . PHE A 1 293 ? 34.301 66.001 29.099 1.00 17.29 ? 293 PHE A CE1 1 ATOM 2221 C CE2 . PHE A 1 293 ? 32.410 64.880 30.146 1.00 14.58 ? 293 PHE A CE2 1 ATOM 2222 C CZ . PHE A 1 293 ? 33.806 65.062 30.011 1.00 14.89 ? 293 PHE A CZ 1 ATOM 2223 N N . GLY A 1 294 ? 28.958 70.204 27.643 1.00 18.83 ? 294 GLY A N 1 ATOM 2224 C CA . GLY A 1 294 ? 28.184 70.990 26.691 1.00 20.40 ? 294 GLY A CA 1 ATOM 2225 C C . GLY A 1 294 ? 27.530 70.230 25.544 1.00 21.23 ? 294 GLY A C 1 ATOM 2226 O O . GLY A 1 294 ? 27.250 70.787 24.444 1.00 23.90 ? 294 GLY A O 1 ATOM 2227 N N . LEU A 1 295 ? 27.278 68.953 25.772 1.00 18.27 ? 295 LEU A N 1 ATOM 2228 C CA . LEU A 1 295 ? 26.583 68.158 24.758 1.00 16.47 ? 295 LEU A CA 1 ATOM 2229 C C . LEU A 1 295 ? 25.377 67.590 25.511 1.00 16.31 ? 295 LEU A C 1 ATOM 2230 O O . LEU A 1 295 ? 25.419 67.409 26.741 1.00 13.73 ? 295 LEU A O 1 ATOM 2231 C CB . LEU A 1 295 ? 27.495 67.062 24.258 1.00 16.30 ? 295 LEU A CB 1 ATOM 2232 C CG . LEU A 1 295 ? 28.818 67.464 23.574 1.00 14.58 ? 295 LEU A CG 1 ATOM 2233 C CD1 . LEU A 1 295 ? 29.592 66.191 23.297 1.00 15.39 ? 295 LEU A CD1 1 ATOM 2234 C CD2 . LEU A 1 295 ? 28.559 68.215 22.250 1.00 15.95 ? 295 LEU A CD2 1 ATOM 2235 N N . SER A 1 296 ? 24.303 67.323 24.788 1.00 15.39 ? 296 SER A N 1 ATOM 2236 C CA . SER A 1 296 ? 23.094 66.812 25.406 1.00 15.84 ? 296 SER A CA 1 ATOM 2237 C C . SER A 1 296 ? 22.478 65.836 24.421 1.00 16.40 ? 296 SER A C 1 ATOM 2238 O O . SER A 1 296 ? 23.002 65.677 23.317 1.00 15.89 ? 296 SER A O 1 ATOM 2239 C CB . SER A 1 296 ? 22.122 67.977 25.662 1.00 12.39 ? 296 SER A CB 1 ATOM 2240 O OG . SER A 1 296 ? 21.883 68.653 24.464 1.00 16.68 ? 296 SER A OG 1 ATOM 2241 N N . CYS A 1 297 ? 21.365 65.197 24.806 1.00 17.70 ? 297 CYS A N 1 ATOM 2242 C CA . CYS A 1 297 ? 20.644 64.270 23.911 1.00 18.08 ? 297 CYS A CA 1 ATOM 2243 C C . CYS A 1 297 ? 19.396 64.932 23.300 1.00 17.52 ? 297 CYS A C 1 ATOM 2244 O O . CYS A 1 297 ? 18.484 65.306 24.038 1.00 20.90 ? 297 CYS A O 1 ATOM 2245 C CB . CYS A 1 297 ? 20.223 63.009 24.667 1.00 18.86 ? 297 CYS A CB 1 ATOM 2246 S SG . CYS A 1 297 ? 21.635 61.865 24.911 1.00 19.56 ? 297 CYS A SG 1 ATOM 2247 N N . PRO A 1 298 ? 19.303 65.007 21.970 1.00 19.51 ? 298 PRO A N 1 ATOM 2248 C CA . PRO A 1 298 ? 18.109 65.654 21.416 1.00 18.05 ? 298 PRO A CA 1 ATOM 2249 C C . PRO A 1 298 ? 16.798 64.879 21.558 1.00 20.18 ? 298 PRO A C 1 ATOM 2250 O O . PRO A 1 298 ? 15.701 65.449 21.280 1.00 18.99 ? 298 PRO A O 1 ATOM 2251 C CB . PRO A 1 298 ? 18.493 65.911 19.965 1.00 19.84 ? 298 PRO A CB 1 ATOM 2252 C CG . PRO A 1 298 ? 19.418 64.839 19.655 1.00 20.01 ? 298 PRO A CG 1 ATOM 2253 C CD . PRO A 1 298 ? 20.274 64.714 20.899 1.00 18.09 ? 298 PRO A CD 1 ATOM 2254 N N . TRP A 1 299 ? 16.904 63.617 21.989 1.00 18.39 ? 299 TRP A N 1 ATOM 2255 C CA . TRP A 1 299 ? 15.713 62.776 22.149 1.00 20.07 ? 299 TRP A CA 1 ATOM 2256 C C . TRP A 1 299 ? 15.199 62.966 23.563 1.00 21.78 ? 299 TRP A C 1 ATOM 2257 O O . TRP A 1 299 ? 14.291 62.248 24.024 1.00 21.59 ? 299 TRP A O 1 ATOM 2258 C CB . TRP A 1 299 ? 16.024 61.296 21.843 1.00 18.41 ? 299 TRP A CB 1 ATOM 2259 C CG . TRP A 1 299 ? 16.390 61.073 20.403 1.00 16.46 ? 299 TRP A CG 1 ATOM 2260 C CD1 . TRP A 1 299 ? 15.562 60.861 19.355 1.00 15.99 ? 299 TRP A CD1 1 ATOM 2261 C CD2 . TRP A 1 299 ? 17.710 61.195 19.848 1.00 15.02 ? 299 TRP A CD2 1 ATOM 2262 N NE1 . TRP A 1 299 ? 16.270 60.844 18.162 1.00 16.18 ? 299 TRP A NE1 1 ATOM 2263 C CE2 . TRP A 1 299 ? 17.598 61.058 18.445 1.00 16.08 ? 299 TRP A CE2 1 ATOM 2264 C CE3 . TRP A 1 299 ? 18.970 61.416 20.411 1.00 13.89 ? 299 TRP A CE3 1 ATOM 2265 C CZ2 . TRP A 1 299 ? 18.710 61.141 17.587 1.00 15.28 ? 299 TRP A CZ2 1 ATOM 2266 C CZ3 . TRP A 1 299 ? 20.064 61.497 19.558 1.00 13.65 ? 299 TRP A CZ3 1 ATOM 2267 C CH2 . TRP A 1 299 ? 19.928 61.366 18.180 1.00 14.31 ? 299 TRP A CH2 1 ATOM 2268 N N . LYS A 1 300 ? 15.805 63.942 24.261 1.00 22.46 ? 300 LYS A N 1 ATOM 2269 C CA . LYS A 1 300 ? 15.368 64.324 25.605 1.00 24.25 ? 300 LYS A CA 1 ATOM 2270 C C . LYS A 1 300 ? 15.605 63.431 26.821 1.00 23.05 ? 300 LYS A C 1 ATOM 2271 O O . LYS A 1 300 ? 15.123 63.735 27.928 1.00 23.99 ? 300 LYS A O 1 ATOM 2272 C CB . LYS A 1 300 ? 13.873 64.705 25.526 1.00 26.05 ? 300 LYS A CB 1 ATOM 2273 C CG . LYS A 1 300 ? 13.623 65.759 24.515 1.00 27.64 ? 300 LYS A CG 1 ATOM 2274 C CD . LYS A 1 300 ? 12.141 66.032 24.309 1.00 29.98 ? 300 LYS A CD 1 ATOM 2275 C CE . LYS A 1 300 ? 11.961 66.966 23.098 1.00 30.95 ? 300 LYS A CE 1 ATOM 2276 N NZ . LYS A 1 300 ? 10.536 67.143 22.645 1.00 32.58 ? 300 LYS A NZ 1 ATOM 2277 N N . VAL A 1 301 ? 16.348 62.346 26.673 1.00 21.96 ? 301 VAL A N 1 ATOM 2278 C CA . VAL A 1 301 ? 16.628 61.507 27.832 1.00 21.59 ? 301 VAL A CA 1 ATOM 2279 C C . VAL A 1 301 ? 18.154 61.458 27.910 1.00 21.97 ? 301 VAL A C 1 ATOM 2280 O O . VAL A 1 301 ? 18.825 60.917 27.044 1.00 22.84 ? 301 VAL A O 1 ATOM 2281 C CB . VAL A 1 301 ? 16.042 60.075 27.696 1.00 22.09 ? 301 VAL A CB 1 ATOM 2282 C CG1 . VAL A 1 301 ? 16.382 59.266 28.915 1.00 20.69 ? 301 VAL A CG1 1 ATOM 2283 C CG2 . VAL A 1 301 ? 14.508 60.164 27.461 1.00 23.12 ? 301 VAL A CG2 1 ATOM 2284 N N . PRO A 1 302 ? 18.719 61.991 28.970 1.00 22.14 ? 302 PRO A N 1 ATOM 2285 C CA . PRO A 1 302 ? 20.171 61.996 29.071 1.00 21.80 ? 302 PRO A CA 1 ATOM 2286 C C . PRO A 1 302 ? 20.812 60.743 29.600 1.00 21.77 ? 302 PRO A C 1 ATOM 2287 O O . PRO A 1 302 ? 20.168 59.871 30.177 1.00 21.99 ? 302 PRO A O 1 ATOM 2288 C CB . PRO A 1 302 ? 20.408 63.145 30.006 1.00 21.77 ? 302 PRO A CB 1 ATOM 2289 C CG . PRO A 1 302 ? 19.306 62.863 31.055 1.00 23.96 ? 302 PRO A CG 1 ATOM 2290 C CD . PRO A 1 302 ? 18.100 62.554 30.184 1.00 22.81 ? 302 PRO A CD 1 ATOM 2291 N N . PRO A 1 303 ? 22.122 60.629 29.397 1.00 19.58 ? 303 PRO A N 1 ATOM 2292 C CA . PRO A 1 303 ? 22.750 59.436 29.942 1.00 20.35 ? 303 PRO A CA 1 ATOM 2293 C C . PRO A 1 303 ? 22.791 59.630 31.469 1.00 21.44 ? 303 PRO A C 1 ATOM 2294 O O . PRO A 1 303 ? 22.676 60.763 31.991 1.00 20.97 ? 303 PRO A O 1 ATOM 2295 C CB . PRO A 1 303 ? 24.144 59.458 29.314 1.00 19.94 ? 303 PRO A CB 1 ATOM 2296 C CG . PRO A 1 303 ? 24.370 60.863 28.914 1.00 20.54 ? 303 PRO A CG 1 ATOM 2297 C CD . PRO A 1 303 ? 23.034 61.409 28.534 1.00 20.40 ? 303 PRO A CD 1 ATOM 2298 N N . ARG A 1 304 ? 22.938 58.537 32.181 1.00 21.27 ? 304 ARG A N 1 ATOM 2299 C CA . ARG A 1 304 ? 23.024 58.606 33.611 1.00 23.02 ? 304 ARG A CA 1 ATOM 2300 C C . ARG A 1 304 ? 24.175 57.716 33.994 1.00 22.34 ? 304 ARG A C 1 ATOM 2301 O O . ARG A 1 304 ? 24.388 56.654 33.374 1.00 20.77 ? 304 ARG A O 1 ATOM 2302 C CB . ARG A 1 304 ? 21.730 58.116 34.253 1.00 26.26 ? 304 ARG A CB 1 ATOM 2303 C CG . ARG A 1 304 ? 20.537 59.008 34.012 1.00 30.15 ? 304 ARG A CG 1 ATOM 2304 C CD . ARG A 1 304 ? 19.434 58.613 34.959 1.00 35.28 ? 304 ARG A CD 1 ATOM 2305 N NE . ARG A 1 304 ? 19.332 57.155 35.049 1.00 39.02 ? 304 ARG A NE 1 ATOM 2306 C CZ . ARG A 1 304 ? 18.567 56.394 34.267 1.00 40.39 ? 304 ARG A CZ 1 ATOM 2307 N NH1 . ARG A 1 304 ? 17.808 56.941 33.323 1.00 41.36 ? 304 ARG A NH1 1 ATOM 2308 N NH2 . ARG A 1 304 ? 18.579 55.074 34.427 1.00 42.16 ? 304 ARG A NH2 1 ATOM 2309 N N . THR A 1 305 ? 24.931 58.142 34.999 1.00 21.62 ? 305 THR A N 1 ATOM 2310 C CA . THR A 1 305 ? 26.062 57.384 35.450 1.00 21.94 ? 305 THR A CA 1 ATOM 2311 C C . THR A 1 305 ? 25.644 55.981 35.831 1.00 21.46 ? 305 THR A C 1 ATOM 2312 O O . THR A 1 305 ? 24.585 55.774 36.434 1.00 22.86 ? 305 THR A O 1 ATOM 2313 C CB . THR A 1 305 ? 26.755 58.091 36.629 1.00 21.73 ? 305 THR A CB 1 ATOM 2314 O OG1 . THR A 1 305 ? 27.180 59.384 36.182 1.00 26.02 ? 305 THR A OG1 1 ATOM 2315 C CG2 . THR A 1 305 ? 27.951 57.311 37.137 1.00 22.10 ? 305 THR A CG2 1 ATOM 2316 N N . ILE A 1 306 ? 26.438 54.998 35.438 1.00 18.77 ? 306 ILE A N 1 ATOM 2317 C CA . ILE A 1 306 ? 26.124 53.626 35.753 1.00 17.63 ? 306 ILE A CA 1 ATOM 2318 C C . ILE A 1 306 ? 26.511 53.358 37.218 1.00 17.59 ? 306 ILE A C 1 ATOM 2319 O O . ILE A 1 306 ? 27.583 53.756 37.669 1.00 17.88 ? 306 ILE A O 1 ATOM 2320 C CB . ILE A 1 306 ? 26.864 52.620 34.788 1.00 16.00 ? 306 ILE A CB 1 ATOM 2321 C CG1 . ILE A 1 306 ? 26.506 52.893 33.317 1.00 15.44 ? 306 ILE A CG1 1 ATOM 2322 C CG2 . ILE A 1 306 ? 26.518 51.162 35.159 1.00 14.56 ? 306 ILE A CG2 1 ATOM 2323 C CD1 . ILE A 1 306 ? 25.043 52.823 33.016 1.00 12.99 ? 306 ILE A CD1 1 ATOM 2324 N N . SER A 1 307 ? 25.600 52.727 37.965 1.00 18.65 ? 307 SER A N 1 ATOM 2325 C CA . SER A 1 307 ? 25.827 52.432 39.383 1.00 20.46 ? 307 SER A CA 1 ATOM 2326 C C . SER A 1 307 ? 25.292 51.035 39.654 1.00 21.15 ? 307 SER A C 1 ATOM 2327 O O . SER A 1 307 ? 24.569 50.476 38.802 1.00 20.71 ? 307 SER A O 1 ATOM 2328 C CB . SER A 1 307 ? 25.021 53.397 40.256 1.00 20.46 ? 307 SER A CB 1 ATOM 2329 O OG . SER A 1 307 ? 23.633 53.175 40.022 1.00 21.80 ? 307 SER A OG 1 ATOM 2330 N N . ASP A 1 308 ? 25.562 50.500 40.852 1.00 22.18 ? 308 ASP A N 1 ATOM 2331 C CA . ASP A 1 308 ? 25.051 49.180 41.152 1.00 23.74 ? 308 ASP A CA 1 ATOM 2332 C C . ASP A 1 308 ? 23.537 49.139 41.188 1.00 22.45 ? 308 ASP A C 1 ATOM 2333 O O . ASP A 1 308 ? 22.965 48.104 40.879 1.00 23.04 ? 308 ASP A O 1 ATOM 2334 C CB . ASP A 1 308 ? 25.635 48.680 42.463 1.00 27.16 ? 308 ASP A CB 1 ATOM 2335 C CG . ASP A 1 308 ? 27.137 48.496 42.375 1.00 32.12 ? 308 ASP A CG 1 ATOM 2336 O OD1 . ASP A 1 308 ? 27.718 49.053 41.411 1.00 35.43 ? 308 ASP A OD1 1 ATOM 2337 O OD2 . ASP A 1 308 ? 27.742 47.821 43.255 1.00 34.25 ? 308 ASP A OD2 1 ATOM 2338 N N . GLN A 1 309 ? 22.889 50.261 41.507 1.00 21.59 ? 309 GLN A N 1 ATOM 2339 C CA . GLN A 1 309 ? 21.430 50.320 41.574 1.00 21.65 ? 309 GLN A CA 1 ATOM 2340 C C . GLN A 1 309 ? 20.761 50.452 40.230 1.00 20.59 ? 309 GLN A C 1 ATOM 2341 O O . GLN A 1 309 ? 19.574 50.173 40.111 1.00 19.76 ? 309 GLN A O 1 ATOM 2342 C CB . GLN A 1 309 ? 20.953 51.506 42.429 1.00 21.69 ? 309 GLN A CB 1 ATOM 2343 C CG . GLN A 1 309 ? 21.394 51.479 43.874 1.00 23.41 ? 309 GLN A CG 1 ATOM 2344 C CD . GLN A 1 309 ? 22.914 51.580 44.014 1.00 25.08 ? 309 GLN A CD 1 ATOM 2345 O OE1 . GLN A 1 309 ? 23.545 52.522 43.492 1.00 25.96 ? 309 GLN A OE1 1 ATOM 2346 N NE2 . GLN A 1 309 ? 23.516 50.610 44.737 1.00 24.90 ? 309 GLN A NE2 1 ATOM 2347 N N . ASN A 1 310 ? 21.477 50.900 39.208 1.00 19.74 ? 310 ASN A N 1 ATOM 2348 C CA . ASN A 1 310 ? 20.810 51.019 37.921 1.00 18.92 ? 310 ASN A CA 1 ATOM 2349 C C . ASN A 1 310 ? 21.446 50.158 36.847 1.00 18.42 ? 310 ASN A C 1 ATOM 2350 O O . ASN A 1 310 ? 20.892 50.054 35.757 1.00 17.71 ? 310 ASN A O 1 ATOM 2351 C CB . ASN A 1 310 ? 20.726 52.513 37.457 1.00 20.24 ? 310 ASN A CB 1 ATOM 2352 C CG . ASN A 1 310 ? 22.074 53.084 36.989 1.00 20.87 ? 310 ASN A CG 1 ATOM 2353 O OD1 . ASN A 1 310 ? 23.020 52.339 36.699 1.00 22.22 ? 310 ASN A OD1 1 ATOM 2354 N ND2 . ASN A 1 310 ? 22.151 54.411 36.905 1.00 21.00 ? 310 ASN A ND2 1 ATOM 2355 N N . VAL A 1 311 ? 22.537 49.476 37.174 1.00 16.86 ? 311 VAL A N 1 ATOM 2356 C CA . VAL A 1 311 ? 23.247 48.703 36.129 1.00 17.09 ? 311 VAL A CA 1 ATOM 2357 C C . VAL A 1 311 ? 22.401 47.601 35.478 1.00 16.94 ? 311 VAL A C 1 ATOM 2358 O O . VAL A 1 311 ? 22.571 47.315 34.274 1.00 18.88 ? 311 VAL A O 1 ATOM 2359 C CB . VAL A 1 311 ? 24.601 48.094 36.663 1.00 17.25 ? 311 VAL A CB 1 ATOM 2360 C CG1 . VAL A 1 311 ? 24.342 46.967 37.630 1.00 18.36 ? 311 VAL A CG1 1 ATOM 2361 C CG2 . VAL A 1 311 ? 25.472 47.587 35.494 1.00 18.41 ? 311 VAL A CG2 1 ATOM 2362 N N . ALA A 1 312 ? 21.453 47.017 36.210 1.00 17.16 ? 312 ALA A N 1 ATOM 2363 C CA . ALA A 1 312 ? 20.637 45.951 35.609 1.00 16.81 ? 312 ALA A CA 1 ATOM 2364 C C . ALA A 1 312 ? 19.691 46.469 34.578 1.00 18.87 ? 312 ALA A C 1 ATOM 2365 O O . ALA A 1 312 ? 19.587 45.918 33.492 1.00 18.98 ? 312 ALA A O 1 ATOM 2366 C CB . ALA A 1 312 ? 19.851 45.188 36.702 1.00 18.34 ? 312 ALA A CB 1 ATOM 2367 N N . ALA A 1 313 ? 18.987 47.542 34.903 1.00 18.64 ? 313 ALA A N 1 ATOM 2368 C CA . ALA A 1 313 ? 18.030 48.142 34.021 1.00 18.71 ? 313 ALA A CA 1 ATOM 2369 C C . ALA A 1 313 ? 18.757 48.727 32.799 1.00 19.30 ? 313 ALA A C 1 ATOM 2370 O O . ALA A 1 313 ? 18.285 48.580 31.680 1.00 19.48 ? 313 ALA A O 1 ATOM 2371 C CB . ALA A 1 313 ? 17.256 49.224 34.777 1.00 17.65 ? 313 ALA A CB 1 ATOM 2372 N N . ARG A 1 314 ? 19.912 49.348 33.000 1.00 18.75 ? 314 ARG A N 1 ATOM 2373 C CA . ARG A 1 314 ? 20.656 49.946 31.890 1.00 18.46 ? 314 ARG A CA 1 ATOM 2374 C C . ARG A 1 314 ? 21.161 48.823 30.949 1.00 17.02 ? 314 ARG A C 1 ATOM 2375 O O . ARG A 1 314 ? 21.104 48.988 29.716 1.00 17.23 ? 314 ARG A O 1 ATOM 2376 C CB . ARG A 1 314 ? 21.844 50.709 32.442 1.00 17.38 ? 314 ARG A CB 1 ATOM 2377 C CG . ARG A 1 314 ? 21.453 51.845 33.414 1.00 21.44 ? 314 ARG A CG 1 ATOM 2378 C CD . ARG A 1 314 ? 21.242 53.122 32.652 1.00 20.66 ? 314 ARG A CD 1 ATOM 2379 N NE . ARG A 1 314 ? 19.890 53.208 32.118 1.00 20.47 ? 314 ARG A NE 1 ATOM 2380 C CZ . ARG A 1 314 ? 19.501 54.097 31.205 1.00 22.14 ? 314 ARG A CZ 1 ATOM 2381 N NH1 . ARG A 1 314 ? 20.360 54.978 30.696 1.00 22.45 ? 314 ARG A NH1 1 ATOM 2382 N NH2 . ARG A 1 314 ? 18.227 54.145 30.810 1.00 21.15 ? 314 ARG A NH2 1 ATOM 2383 N N . SER A 1 315 ? 21.660 47.732 31.540 1.00 17.67 ? 315 SER A N 1 ATOM 2384 C CA . SER A 1 315 ? 22.150 46.574 30.755 1.00 18.31 ? 315 SER A CA 1 ATOM 2385 C C . SER A 1 315 ? 20.987 45.971 29.995 1.00 19.00 ? 315 SER A C 1 ATOM 2386 O O . SER A 1 315 ? 21.146 45.610 28.833 1.00 20.12 ? 315 SER A O 1 ATOM 2387 C CB . SER A 1 315 ? 22.809 45.511 31.637 1.00 18.03 ? 315 SER A CB 1 ATOM 2388 O OG . SER A 1 315 ? 23.944 46.058 32.302 1.00 19.31 ? 315 SER A OG 1 ATOM 2389 N N . ASP A 1 316 ? 19.817 45.830 30.615 1.00 18.34 ? 316 ASP A N 1 ATOM 2390 C CA . ASP A 1 316 ? 18.649 45.301 29.899 1.00 18.73 ? 316 ASP A CA 1 ATOM 2391 C C . ASP A 1 316 ? 18.391 46.099 28.627 1.00 17.81 ? 316 ASP A C 1 ATOM 2392 O O . ASP A 1 316 ? 18.093 45.539 27.552 1.00 17.51 ? 316 ASP A O 1 ATOM 2393 C CB . ASP A 1 316 ? 17.355 45.471 30.708 1.00 21.23 ? 316 ASP A CB 1 ATOM 2394 C CG . ASP A 1 316 ? 17.293 44.622 31.942 1.00 22.41 ? 316 ASP A CG 1 ATOM 2395 O OD1 . ASP A 1 316 ? 18.074 43.655 32.066 1.00 20.14 ? 316 ASP A OD1 1 ATOM 2396 O OD2 . ASP A 1 316 ? 16.388 44.946 32.778 1.00 23.23 ? 316 ASP A OD2 1 ATOM 2397 N N . LEU A 1 317 ? 18.458 47.419 28.773 1.00 16.81 ? 317 LEU A N 1 ATOM 2398 C CA . LEU A 1 317 ? 18.165 48.309 27.674 1.00 16.21 ? 317 LEU A CA 1 ATOM 2399 C C . LEU A 1 317 ? 19.207 48.219 26.553 1.00 14.16 ? 317 LEU A C 1 ATOM 2400 O O . LEU A 1 317 ? 18.842 48.181 25.359 1.00 15.34 ? 317 LEU A O 1 ATOM 2401 C CB . LEU A 1 317 ? 18.115 49.752 28.163 1.00 17.32 ? 317 LEU A CB 1 ATOM 2402 C CG . LEU A 1 317 ? 16.805 50.346 28.615 1.00 20.86 ? 317 LEU A CG 1 ATOM 2403 C CD1 . LEU A 1 317 ? 17.095 51.758 29.160 1.00 20.62 ? 317 LEU A CD1 1 ATOM 2404 C CD2 . LEU A 1 317 ? 15.811 50.372 27.454 1.00 21.71 ? 317 LEU A CD2 1 ATOM 2405 N N . LEU A 1 318 ? 20.473 48.185 26.960 1.00 14.48 ? 318 LEU A N 1 ATOM 2406 C CA . LEU A 1 318 ? 21.588 48.186 26.007 1.00 13.23 ? 318 LEU A CA 1 ATOM 2407 C C . LEU A 1 318 ? 21.707 46.863 25.282 1.00 12.96 ? 318 LEU A C 1 ATOM 2408 O O . LEU A 1 318 ? 21.824 46.867 24.032 1.00 13.38 ? 318 LEU A O 1 ATOM 2409 C CB . LEU A 1 318 ? 22.903 48.524 26.761 1.00 13.21 ? 318 LEU A CB 1 ATOM 2410 C CG . LEU A 1 318 ? 24.156 48.622 25.858 1.00 10.30 ? 318 LEU A CG 1 ATOM 2411 C CD1 . LEU A 1 318 ? 23.968 49.723 24.768 1.00 11.13 ? 318 LEU A CD1 1 ATOM 2412 C CD2 . LEU A 1 318 ? 25.391 48.914 26.718 1.00 13.10 ? 318 LEU A CD2 1 ATOM 2413 N N . VAL A 1 319 ? 21.671 45.740 26.021 1.00 11.65 ? 319 VAL A N 1 ATOM 2414 C CA . VAL A 1 319 ? 21.735 44.414 25.394 1.00 12.03 ? 319 VAL A CA 1 ATOM 2415 C C . VAL A 1 319 ? 20.578 44.255 24.412 1.00 10.13 ? 319 VAL A C 1 ATOM 2416 O O . VAL A 1 319 ? 20.735 43.683 23.307 1.00 12.53 ? 319 VAL A O 1 ATOM 2417 C CB . VAL A 1 319 ? 21.715 43.313 26.491 1.00 12.35 ? 319 VAL A CB 1 ATOM 2418 C CG1 . VAL A 1 319 ? 21.594 41.907 25.869 1.00 13.78 ? 319 VAL A CG1 1 ATOM 2419 C CG2 . VAL A 1 319 ? 22.978 43.428 27.319 1.00 14.25 ? 319 VAL A CG2 1 ATOM 2420 N N . ASP A 1 320 ? 19.401 44.754 24.768 1.00 12.27 ? 320 ASP A N 1 ATOM 2421 C CA . ASP A 1 320 ? 18.261 44.707 23.837 1.00 12.86 ? 320 ASP A CA 1 ATOM 2422 C C . ASP A 1 320 ? 18.594 45.433 22.496 1.00 11.49 ? 320 ASP A C 1 ATOM 2423 O O . ASP A 1 320 ? 18.236 44.943 21.395 1.00 11.77 ? 320 ASP A O 1 ATOM 2424 C CB . ASP A 1 320 ? 16.981 45.297 24.494 1.00 15.61 ? 320 ASP A CB 1 ATOM 2425 C CG . ASP A 1 320 ? 15.790 45.377 23.536 1.00 15.01 ? 320 ASP A CG 1 ATOM 2426 O OD1 . ASP A 1 320 ? 15.251 44.292 23.136 1.00 16.83 ? 320 ASP A OD1 1 ATOM 2427 O OD2 . ASP A 1 320 ? 15.344 46.513 23.203 1.00 16.93 ? 320 ASP A OD2 1 ATOM 2428 N N . GLN A 1 321 ? 19.262 46.603 22.564 1.00 11.75 ? 321 GLN A N 1 ATOM 2429 C CA . GLN A 1 321 ? 19.626 47.342 21.314 1.00 10.65 ? 321 GLN A CA 1 ATOM 2430 C C . GLN A 1 321 ? 20.641 46.487 20.539 1.00 7.90 ? 321 GLN A C 1 ATOM 2431 O O . GLN A 1 321 ? 20.523 46.342 19.318 1.00 10.55 ? 321 GLN A O 1 ATOM 2432 C CB . GLN A 1 321 ? 20.286 48.702 21.651 1.00 11.19 ? 321 GLN A CB 1 ATOM 2433 C CG . GLN A 1 321 ? 19.248 49.748 22.121 1.00 13.57 ? 321 GLN A CG 1 ATOM 2434 C CD . GLN A 1 321 ? 18.193 49.988 21.088 1.00 14.29 ? 321 GLN A CD 1 ATOM 2435 O OE1 . GLN A 1 321 ? 18.500 50.393 19.979 1.00 13.88 ? 321 GLN A OE1 1 ATOM 2436 N NE2 . GLN A 1 321 ? 16.899 49.764 21.445 1.00 14.90 ? 321 GLN A NE2 1 ATOM 2437 N N . TRP A 1 322 ? 21.644 45.994 21.250 1.00 9.42 ? 322 TRP A N 1 ATOM 2438 C CA . TRP A 1 322 ? 22.654 45.108 20.610 1.00 9.42 ? 322 TRP A CA 1 ATOM 2439 C C . TRP A 1 322 ? 22.080 43.874 19.939 1.00 8.57 ? 322 TRP A C 1 ATOM 2440 O O . TRP A 1 322 ? 22.430 43.533 18.827 1.00 11.03 ? 322 TRP A O 1 ATOM 2441 C CB . TRP A 1 322 ? 23.669 44.607 21.638 1.00 9.64 ? 322 TRP A CB 1 ATOM 2442 C CG . TRP A 1 322 ? 24.589 45.653 22.233 1.00 10.20 ? 322 TRP A CG 1 ATOM 2443 C CD1 . TRP A 1 322 ? 24.778 46.944 21.790 1.00 11.76 ? 322 TRP A CD1 1 ATOM 2444 C CD2 . TRP A 1 322 ? 25.499 45.463 23.337 1.00 8.94 ? 322 TRP A CD2 1 ATOM 2445 N NE1 . TRP A 1 322 ? 25.777 47.558 22.561 1.00 11.79 ? 322 TRP A NE1 1 ATOM 2446 C CE2 . TRP A 1 322 ? 26.223 46.677 23.504 1.00 10.34 ? 322 TRP A CE2 1 ATOM 2447 C CE3 . TRP A 1 322 ? 25.771 44.372 24.200 1.00 13.12 ? 322 TRP A CE3 1 ATOM 2448 C CZ2 . TRP A 1 322 ? 27.202 46.835 24.498 1.00 12.11 ? 322 TRP A CZ2 1 ATOM 2449 C CZ3 . TRP A 1 322 ? 26.733 44.527 25.177 1.00 13.49 ? 322 TRP A CZ3 1 ATOM 2450 C CH2 . TRP A 1 322 ? 27.446 45.770 25.316 1.00 11.30 ? 322 TRP A CH2 1 ATOM 2451 N N . LYS A 1 323 ? 21.103 43.242 20.578 1.00 9.78 ? 323 LYS A N 1 ATOM 2452 C CA . LYS A 1 323 ? 20.517 42.038 19.955 1.00 11.44 ? 323 LYS A CA 1 ATOM 2453 C C . LYS A 1 323 ? 19.678 42.402 18.731 1.00 11.49 ? 323 LYS A C 1 ATOM 2454 O O . LYS A 1 323 ? 19.578 41.622 17.801 1.00 11.49 ? 323 LYS A O 1 ATOM 2455 C CB . LYS A 1 323 ? 19.729 41.216 21.004 1.00 11.42 ? 323 LYS A CB 1 ATOM 2456 C CG . LYS A 1 323 ? 20.696 40.614 21.976 1.00 13.50 ? 323 LYS A CG 1 ATOM 2457 C CD . LYS A 1 323 ? 20.005 39.810 23.071 1.00 17.63 ? 323 LYS A CD 1 ATOM 2458 C CE . LYS A 1 323 ? 21.010 38.805 23.710 1.00 19.93 ? 323 LYS A CE 1 ATOM 2459 N NZ . LYS A 1 323 ? 20.250 37.907 24.647 1.00 21.25 ? 323 LYS A NZ 1 ATOM 2460 N N . LYS A 1 324 ? 19.086 43.598 18.718 1.00 9.57 ? 324 LYS A N 1 ATOM 2461 C CA . LYS A 1 324 ? 18.323 44.078 17.578 1.00 10.49 ? 324 LYS A CA 1 ATOM 2462 C C . LYS A 1 324 ? 19.310 44.371 16.418 1.00 10.65 ? 324 LYS A C 1 ATOM 2463 O O . LYS A 1 324 ? 19.059 43.940 15.258 1.00 12.22 ? 324 LYS A O 1 ATOM 2464 C CB . LYS A 1 324 ? 17.506 45.329 17.964 1.00 11.22 ? 324 LYS A CB 1 ATOM 2465 C CG . LYS A 1 324 ? 16.234 44.939 18.789 1.00 10.32 ? 324 LYS A CG 1 ATOM 2466 C CD . LYS A 1 324 ? 15.593 46.225 19.356 1.00 11.94 ? 324 LYS A CD 1 ATOM 2467 C CE . LYS A 1 324 ? 14.305 45.780 20.090 1.00 13.12 ? 324 LYS A CE 1 ATOM 2468 N NZ . LYS A 1 324 ? 13.740 46.884 20.874 1.00 16.08 ? 324 LYS A NZ 1 ATOM 2469 N N . LYS A 1 325 ? 20.432 45.058 16.723 1.00 9.57 ? 325 LYS A N 1 ATOM 2470 C CA . LYS A 1 325 ? 21.419 45.364 15.706 1.00 7.86 ? 325 LYS A CA 1 ATOM 2471 C C . LYS A 1 325 ? 21.971 43.999 15.175 1.00 9.49 ? 325 LYS A C 1 ATOM 2472 O O . LYS A 1 325 ? 22.175 43.848 13.971 1.00 9.55 ? 325 LYS A O 1 ATOM 2473 C CB . LYS A 1 325 ? 22.542 46.211 16.321 1.00 9.21 ? 325 LYS A CB 1 ATOM 2474 C CG . LYS A 1 325 ? 23.475 46.698 15.246 1.00 10.10 ? 325 LYS A CG 1 ATOM 2475 C CD . LYS A 1 325 ? 24.512 47.694 15.763 1.00 10.46 ? 325 LYS A CD 1 ATOM 2476 C CE . LYS A 1 325 ? 25.326 48.328 14.596 1.00 10.90 ? 325 LYS A CE 1 ATOM 2477 N NZ . LYS A 1 325 ? 26.534 49.007 15.178 1.00 10.65 ? 325 LYS A NZ 1 ATOM 2478 N N . ALA A 1 326 ? 22.172 43.027 16.059 1.00 9.74 ? 326 ALA A N 1 ATOM 2479 C CA . ALA A 1 326 ? 22.742 41.725 15.653 1.00 10.51 ? 326 ALA A CA 1 ATOM 2480 C C . ALA A 1 326 ? 21.804 40.978 14.700 1.00 11.39 ? 326 ALA A C 1 ATOM 2481 O O . ALA A 1 326 ? 22.265 40.168 13.909 1.00 10.94 ? 326 ALA A O 1 ATOM 2482 C CB . ALA A 1 326 ? 23.012 40.901 16.852 1.00 9.26 ? 326 ALA A CB 1 ATOM 2483 N N . GLU A 1 327 ? 20.519 41.287 14.734 1.00 10.83 ? 327 GLU A N 1 ATOM 2484 C CA . GLU A 1 327 ? 19.591 40.647 13.783 1.00 12.41 ? 327 GLU A CA 1 ATOM 2485 C C . GLU A 1 327 ? 19.839 40.997 12.322 1.00 12.66 ? 327 GLU A C 1 ATOM 2486 O O . GLU A 1 327 ? 19.387 40.251 11.430 1.00 13.90 ? 327 GLU A O 1 ATOM 2487 C CB . GLU A 1 327 ? 18.144 41.031 14.058 1.00 14.07 ? 327 GLU A CB 1 ATOM 2488 C CG . GLU A 1 327 ? 17.479 40.237 15.117 1.00 17.99 ? 327 GLU A CG 1 ATOM 2489 C CD . GLU A 1 327 ? 17.499 38.728 14.839 1.00 18.48 ? 327 GLU A CD 1 ATOM 2490 O OE1 . GLU A 1 327 ? 16.845 38.222 13.901 1.00 19.26 ? 327 GLU A OE1 1 ATOM 2491 O OE2 . GLU A 1 327 ? 18.220 38.044 15.548 1.00 16.87 ? 327 GLU A OE2 1 ATOM 2492 N N . LEU A 1 328 ? 20.554 42.107 12.052 1.00 10.86 ? 328 LEU A N 1 ATOM 2493 C CA . LEU A 1 328 ? 20.775 42.573 10.689 1.00 10.15 ? 328 LEU A CA 1 ATOM 2494 C C . LEU A 1 328 ? 21.980 41.943 10.056 1.00 10.49 ? 328 LEU A C 1 ATOM 2495 O O . LEU A 1 328 ? 22.281 42.217 8.899 1.00 11.01 ? 328 LEU A O 1 ATOM 2496 C CB . LEU A 1 328 ? 20.960 44.115 10.693 1.00 9.22 ? 328 LEU A CB 1 ATOM 2497 C CG . LEU A 1 328 ? 19.845 44.876 11.444 1.00 9.37 ? 328 LEU A CG 1 ATOM 2498 C CD1 . LEU A 1 328 ? 20.084 46.386 11.296 1.00 10.16 ? 328 LEU A CD1 1 ATOM 2499 C CD2 . LEU A 1 328 ? 18.447 44.437 10.983 1.00 11.52 ? 328 LEU A CD2 1 ATOM 2500 N N . TYR A 1 329 ? 22.666 41.100 10.808 1.00 8.77 ? 329 TYR A N 1 ATOM 2501 C CA . TYR A 1 329 ? 23.918 40.471 10.356 1.00 9.17 ? 329 TYR A CA 1 ATOM 2502 C C . TYR A 1 329 ? 23.916 38.949 10.525 1.00 10.19 ? 329 TYR A C 1 ATOM 2503 O O . TYR A 1 329 ? 23.091 38.434 11.281 1.00 11.39 ? 329 TYR A O 1 ATOM 2504 C CB . TYR A 1 329 ? 25.145 41.141 11.100 1.00 8.14 ? 329 TYR A CB 1 ATOM 2505 C CG . TYR A 1 329 ? 25.361 42.602 10.749 1.00 10.02 ? 329 TYR A CG 1 ATOM 2506 C CD1 . TYR A 1 329 ? 26.140 42.966 9.636 1.00 9.36 ? 329 TYR A CD1 1 ATOM 2507 C CD2 . TYR A 1 329 ? 24.772 43.635 11.494 1.00 12.17 ? 329 TYR A CD2 1 ATOM 2508 C CE1 . TYR A 1 329 ? 26.310 44.312 9.268 1.00 10.44 ? 329 TYR A CE1 1 ATOM 2509 C CE2 . TYR A 1 329 ? 24.963 44.987 11.142 1.00 11.44 ? 329 TYR A CE2 1 ATOM 2510 C CZ . TYR A 1 329 ? 25.722 45.298 10.013 1.00 9.13 ? 329 TYR A CZ 1 ATOM 2511 O OH . TYR A 1 329 ? 25.739 46.610 9.605 1.00 10.39 ? 329 TYR A OH 1 ATOM 2512 N N . ARG A 1 330 ? 24.853 38.265 9.877 1.00 9.30 ? 330 ARG A N 1 ATOM 2513 C CA . ARG A 1 330 ? 24.866 36.806 9.870 1.00 10.96 ? 330 ARG A CA 1 ATOM 2514 C C . ARG A 1 330 ? 25.676 36.073 10.915 1.00 12.23 ? 330 ARG A C 1 ATOM 2515 O O . ARG A 1 330 ? 25.496 34.856 11.056 1.00 12.44 ? 330 ARG A O 1 ATOM 2516 C CB . ARG A 1 330 ? 25.302 36.306 8.479 1.00 11.97 ? 330 ARG A CB 1 ATOM 2517 C CG . ARG A 1 330 ? 24.370 36.831 7.397 1.00 9.62 ? 330 ARG A CG 1 ATOM 2518 C CD . ARG A 1 330 ? 24.700 36.306 6.003 1.00 12.06 ? 330 ARG A CD 1 ATOM 2519 N NE . ARG A 1 330 ? 23.721 36.825 5.051 1.00 11.22 ? 330 ARG A NE 1 ATOM 2520 C CZ . ARG A 1 330 ? 23.483 36.341 3.835 1.00 13.77 ? 330 ARG A CZ 1 ATOM 2521 N NH1 . ARG A 1 330 ? 24.174 35.291 3.387 1.00 14.61 ? 330 ARG A NH1 1 ATOM 2522 N NH2 . ARG A 1 330 ? 22.604 36.948 3.043 1.00 13.38 ? 330 ARG A NH2 1 ATOM 2523 N N . THR A 1 331 ? 26.614 36.713 11.606 1.00 11.46 ? 331 THR A N 1 ATOM 2524 C CA . THR A 1 331 ? 27.385 35.953 12.605 1.00 9.71 ? 331 THR A CA 1 ATOM 2525 C C . THR A 1 331 ? 26.976 36.317 13.999 1.00 10.20 ? 331 THR A C 1 ATOM 2526 O O . THR A 1 331 ? 26.079 37.125 14.172 1.00 11.96 ? 331 THR A O 1 ATOM 2527 C CB . THR A 1 331 ? 28.925 36.164 12.470 1.00 11.96 ? 331 THR A CB 1 ATOM 2528 O OG1 . THR A 1 331 ? 29.324 37.465 12.971 1.00 10.92 ? 331 THR A OG1 1 ATOM 2529 C CG2 . THR A 1 331 ? 29.299 35.993 10.968 1.00 10.92 ? 331 THR A CG2 1 ATOM 2530 N N . ASN A 1 332 ? 27.664 35.706 14.977 1.00 10.70 ? 332 ASN A N 1 ATOM 2531 C CA . ASN A 1 332 ? 27.420 35.979 16.408 1.00 12.62 ? 332 ASN A CA 1 ATOM 2532 C C . ASN A 1 332 ? 28.482 36.946 16.948 1.00 13.13 ? 332 ASN A C 1 ATOM 2533 O O . ASN A 1 332 ? 28.751 36.940 18.169 1.00 10.44 ? 332 ASN A O 1 ATOM 2534 C CB . ASN A 1 332 ? 27.416 34.682 17.262 1.00 12.95 ? 332 ASN A CB 1 ATOM 2535 C CG . ASN A 1 332 ? 28.765 34.035 17.359 1.00 16.26 ? 332 ASN A CG 1 ATOM 2536 O OD1 . ASN A 1 332 ? 29.592 34.157 16.455 1.00 18.88 ? 332 ASN A OD1 1 ATOM 2537 N ND2 . ASN A 1 332 ? 29.015 33.320 18.476 1.00 20.01 ? 332 ASN A ND2 1 ATOM 2538 N N . VAL A 1 333 ? 29.082 37.751 16.053 1.00 9.73 ? 333 VAL A N 1 ATOM 2539 C CA . VAL A 1 333 ? 30.105 38.726 16.395 1.00 10.49 ? 333 VAL A CA 1 ATOM 2540 C C . VAL A 1 333 ? 29.530 40.085 15.965 1.00 9.94 ? 333 VAL A C 1 ATOM 2541 O O . VAL A 1 333 ? 29.191 40.260 14.768 1.00 11.88 ? 333 VAL A O 1 ATOM 2542 C CB . VAL A 1 333 ? 31.395 38.441 15.592 1.00 10.00 ? 333 VAL A CB 1 ATOM 2543 C CG1 . VAL A 1 333 ? 32.480 39.505 15.909 1.00 12.58 ? 333 VAL A CG1 1 ATOM 2544 C CG2 . VAL A 1 333 ? 31.888 37.035 15.859 1.00 12.43 ? 333 VAL A CG2 1 ATOM 2545 N N . LEU A 1 334 ? 29.391 41.014 16.931 1.00 9.25 ? 334 LEU A N 1 ATOM 2546 C CA . LEU A 1 334 ? 28.759 42.328 16.715 1.00 7.43 ? 334 LEU A CA 1 ATOM 2547 C C . LEU A 1 334 ? 29.734 43.521 16.873 1.00 8.38 ? 334 LEU A C 1 ATOM 2548 O O . LEU A 1 334 ? 30.457 43.592 17.865 1.00 10.35 ? 334 LEU A O 1 ATOM 2549 C CB . LEU A 1 334 ? 27.553 42.475 17.673 1.00 7.58 ? 334 LEU A CB 1 ATOM 2550 C CG . LEU A 1 334 ? 26.708 43.721 17.452 1.00 8.56 ? 334 LEU A CG 1 ATOM 2551 C CD1 . LEU A 1 334 ? 25.914 43.621 16.098 1.00 10.03 ? 334 LEU A CD1 1 ATOM 2552 C CD2 . LEU A 1 334 ? 25.764 43.889 18.752 1.00 9.48 ? 334 LEU A CD2 1 ATOM 2553 N N . LEU A 1 335 ? 29.753 44.415 15.902 1.00 8.91 ? 335 LEU A N 1 ATOM 2554 C CA . LEU A 1 335 ? 30.625 45.598 15.895 1.00 6.66 ? 335 LEU A CA 1 ATOM 2555 C C . LEU A 1 335 ? 29.803 46.777 16.479 1.00 8.07 ? 335 LEU A C 1 ATOM 2556 O O . LEU A 1 335 ? 28.753 47.084 15.957 1.00 7.63 ? 335 LEU A O 1 ATOM 2557 C CB . LEU A 1 335 ? 31.060 45.960 14.440 1.00 8.23 ? 335 LEU A CB 1 ATOM 2558 C CG . LEU A 1 335 ? 31.895 47.242 14.349 1.00 8.33 ? 335 LEU A CG 1 ATOM 2559 C CD1 . LEU A 1 335 ? 33.198 47.120 15.086 1.00 11.71 ? 335 LEU A CD1 1 ATOM 2560 C CD2 . LEU A 1 335 ? 32.006 47.591 12.948 1.00 10.48 ? 335 LEU A CD2 1 ATOM 2561 N N . ILE A 1 336 ? 30.301 47.384 17.550 1.00 7.02 ? 336 ILE A N 1 ATOM 2562 C CA . ILE A 1 336 ? 29.659 48.553 18.100 1.00 8.09 ? 336 ILE A CA 1 ATOM 2563 C C . ILE A 1 336 ? 30.679 49.714 18.134 1.00 7.46 ? 336 ILE A C 1 ATOM 2564 O O . ILE A 1 336 ? 31.464 49.814 19.061 1.00 9.67 ? 336 ILE A O 1 ATOM 2565 C CB . ILE A 1 336 ? 29.184 48.274 19.566 1.00 9.06 ? 336 ILE A CB 1 ATOM 2566 C CG1 . ILE A 1 336 ? 28.143 47.130 19.586 1.00 10.27 ? 336 ILE A CG1 1 ATOM 2567 C CG2 . ILE A 1 336 ? 28.497 49.537 20.112 1.00 10.08 ? 336 ILE A CG2 1 ATOM 2568 C CD1 . ILE A 1 336 ? 26.826 47.400 18.797 1.00 8.20 ? 336 ILE A CD1 1 ATOM 2569 N N . PRO A 1 337 ? 30.727 50.548 17.093 1.00 7.44 ? 337 PRO A N 1 ATOM 2570 C CA . PRO A 1 337 ? 31.682 51.680 17.165 1.00 8.23 ? 337 PRO A CA 1 ATOM 2571 C C . PRO A 1 337 ? 31.260 52.574 18.373 1.00 9.23 ? 337 PRO A C 1 ATOM 2572 O O . PRO A 1 337 ? 30.068 52.696 18.693 1.00 9.61 ? 337 PRO A O 1 ATOM 2573 C CB . PRO A 1 337 ? 31.450 52.447 15.863 1.00 7.28 ? 337 PRO A CB 1 ATOM 2574 C CG . PRO A 1 337 ? 30.915 51.398 14.940 1.00 8.63 ? 337 PRO A CG 1 ATOM 2575 C CD . PRO A 1 337 ? 29.931 50.625 15.861 1.00 8.87 ? 337 PRO A CD 1 ATOM 2576 N N . LEU A 1 338 ? 32.247 53.173 19.038 1.00 9.74 ? 338 LEU A N 1 ATOM 2577 C CA . LEU A 1 338 ? 31.989 54.133 20.122 1.00 9.20 ? 338 LEU A CA 1 ATOM 2578 C C . LEU A 1 338 ? 32.802 55.423 19.919 1.00 8.73 ? 338 LEU A C 1 ATOM 2579 O O . LEU A 1 338 ? 33.963 55.540 20.347 1.00 9.51 ? 338 LEU A O 1 ATOM 2580 C CB . LEU A 1 338 ? 32.298 53.477 21.466 1.00 9.81 ? 338 LEU A CB 1 ATOM 2581 C CG . LEU A 1 338 ? 31.909 54.373 22.664 1.00 8.66 ? 338 LEU A CG 1 ATOM 2582 C CD1 . LEU A 1 338 ? 30.389 54.167 22.979 1.00 10.49 ? 338 LEU A CD1 1 ATOM 2583 C CD2 . LEU A 1 338 ? 32.670 53.853 23.904 1.00 10.54 ? 338 LEU A CD2 1 ATOM 2584 N N . GLY A 1 339 ? 32.202 56.376 19.195 1.00 9.97 ? 339 GLY A N 1 ATOM 2585 C CA . GLY A 1 339 ? 32.958 57.617 18.910 1.00 7.53 ? 339 GLY A CA 1 ATOM 2586 C C . GLY A 1 339 ? 32.137 58.602 18.081 1.00 8.33 ? 339 GLY A C 1 ATOM 2587 O O . GLY A 1 339 ? 30.921 58.384 17.817 1.00 9.39 ? 339 GLY A O 1 ATOM 2588 N N . ASP A 1 340 ? 32.767 59.744 17.720 1.00 8.32 ? 340 ASP A N 1 ATOM 2589 C CA . ASP A 1 340 ? 32.129 60.809 16.973 1.00 9.00 ? 340 ASP A CA 1 ATOM 2590 C C . ASP A 1 340 ? 33.276 61.745 16.556 1.00 7.90 ? 340 ASP A C 1 ATOM 2591 O O . ASP A 1 340 ? 34.467 61.423 16.740 1.00 9.46 ? 340 ASP A O 1 ATOM 2592 C CB . ASP A 1 340 ? 31.102 61.501 17.894 1.00 8.53 ? 340 ASP A CB 1 ATOM 2593 C CG . ASP A 1 340 ? 29.994 62.265 17.169 1.00 10.01 ? 340 ASP A CG 1 ATOM 2594 O OD1 . ASP A 1 340 ? 30.122 62.697 15.998 1.00 10.31 ? 340 ASP A OD1 1 ATOM 2595 O OD2 . ASP A 1 340 ? 28.954 62.422 17.797 1.00 12.67 ? 340 ASP A OD2 1 ATOM 2596 N N . ASP A 1 341 ? 32.909 62.932 16.148 1.00 8.94 ? 341 ASP A N 1 ATOM 2597 C CA . ASP A 1 341 ? 33.908 63.848 15.632 1.00 9.40 ? 341 ASP A CA 1 ATOM 2598 C C . ASP A 1 341 ? 34.750 64.448 16.730 1.00 9.88 ? 341 ASP A C 1 ATOM 2599 O O . ASP A 1 341 ? 34.231 64.953 17.699 1.00 10.30 ? 341 ASP A O 1 ATOM 2600 C CB . ASP A 1 341 ? 33.196 64.962 14.796 1.00 9.56 ? 341 ASP A CB 1 ATOM 2601 C CG . ASP A 1 341 ? 32.593 64.447 13.489 1.00 12.73 ? 341 ASP A CG 1 ATOM 2602 O OD1 . ASP A 1 341 ? 32.627 63.228 13.218 1.00 11.22 ? 341 ASP A OD1 1 ATOM 2603 O OD2 . ASP A 1 341 ? 32.144 65.277 12.661 1.00 11.41 ? 341 ASP A OD2 1 ATOM 2604 N N . PHE A 1 342 ? 36.074 64.417 16.531 1.00 8.56 ? 342 PHE A N 1 ATOM 2605 C CA . PHE A 1 342 ? 37.051 64.982 17.437 1.00 9.81 ? 342 PHE A CA 1 ATOM 2606 C C . PHE A 1 342 ? 36.766 64.565 18.896 1.00 10.41 ? 342 PHE A C 1 ATOM 2607 O O . PHE A 1 342 ? 36.957 65.345 19.853 1.00 12.33 ? 342 PHE A O 1 ATOM 2608 C CB . PHE A 1 342 ? 37.095 66.525 17.240 1.00 8.59 ? 342 PHE A CB 1 ATOM 2609 C CG . PHE A 1 342 ? 37.758 66.933 15.961 1.00 10.42 ? 342 PHE A CG 1 ATOM 2610 C CD1 . PHE A 1 342 ? 39.148 66.865 15.814 1.00 8.49 ? 342 PHE A CD1 1 ATOM 2611 C CD2 . PHE A 1 342 ? 36.985 67.355 14.879 1.00 8.69 ? 342 PHE A CD2 1 ATOM 2612 C CE1 . PHE A 1 342 ? 39.706 67.248 14.565 1.00 8.97 ? 342 PHE A CE1 1 ATOM 2613 C CE2 . PHE A 1 342 ? 37.524 67.708 13.682 1.00 9.74 ? 342 PHE A CE2 1 ATOM 2614 C CZ . PHE A 1 342 ? 38.862 67.671 13.497 1.00 9.31 ? 342 PHE A CZ 1 ATOM 2615 N N . ARG A 1 343 ? 36.327 63.309 19.060 1.00 10.15 ? 343 ARG A N 1 ATOM 2616 C CA . ARG A 1 343 ? 36.090 62.775 20.406 1.00 9.32 ? 343 ARG A CA 1 ATOM 2617 C C . ARG A 1 343 ? 37.392 62.303 21.132 1.00 10.95 ? 343 ARG A C 1 ATOM 2618 O O . ARG A 1 343 ? 38.511 62.284 20.574 1.00 9.20 ? 343 ARG A O 1 ATOM 2619 C CB . ARG A 1 343 ? 35.085 61.594 20.345 1.00 9.11 ? 343 ARG A CB 1 ATOM 2620 C CG . ARG A 1 343 ? 33.637 62.029 20.145 1.00 10.97 ? 343 ARG A CG 1 ATOM 2621 C CD . ARG A 1 343 ? 33.157 63.013 21.227 1.00 10.25 ? 343 ARG A CD 1 ATOM 2622 N NE . ARG A 1 343 ? 31.705 63.247 21.152 1.00 10.21 ? 343 ARG A NE 1 ATOM 2623 C CZ . ARG A 1 343 ? 30.773 62.551 21.818 1.00 11.36 ? 343 ARG A CZ 1 ATOM 2624 N NH1 . ARG A 1 343 ? 31.086 61.551 22.600 1.00 9.13 ? 343 ARG A NH1 1 ATOM 2625 N NH2 . ARG A 1 343 ? 29.502 62.943 21.755 1.00 9.51 ? 343 ARG A NH2 1 ATOM 2626 N N . PHE A 1 344 ? 37.245 61.949 22.405 1.00 10.98 ? 344 PHE A N 1 ATOM 2627 C CA . PHE A 1 344 ? 38.351 61.441 23.249 1.00 11.64 ? 344 PHE A CA 1 ATOM 2628 C C . PHE A 1 344 ? 39.446 62.465 23.390 1.00 11.97 ? 344 PHE A C 1 ATOM 2629 O O . PHE A 1 344 ? 40.659 62.178 23.307 1.00 13.36 ? 344 PHE A O 1 ATOM 2630 C CB . PHE A 1 344 ? 38.803 60.095 22.671 1.00 9.43 ? 344 PHE A CB 1 ATOM 2631 C CG . PHE A 1 344 ? 37.779 59.037 22.905 1.00 10.42 ? 344 PHE A CG 1 ATOM 2632 C CD1 . PHE A 1 344 ? 37.597 58.535 24.206 1.00 12.31 ? 344 PHE A CD1 1 ATOM 2633 C CD2 . PHE A 1 344 ? 36.980 58.592 21.874 1.00 9.81 ? 344 PHE A CD2 1 ATOM 2634 C CE1 . PHE A 1 344 ? 36.565 57.556 24.463 1.00 13.32 ? 344 PHE A CE1 1 ATOM 2635 C CE2 . PHE A 1 344 ? 35.972 57.635 22.101 1.00 12.45 ? 344 PHE A CE2 1 ATOM 2636 C CZ . PHE A 1 344 ? 35.775 57.136 23.391 1.00 12.65 ? 344 PHE A CZ 1 ATOM 2637 N N . LYS A 1 345 ? 38.987 63.687 23.600 1.00 12.48 ? 345 LYS A N 1 ATOM 2638 C CA . LYS A 1 345 ? 39.833 64.834 23.782 1.00 13.53 ? 345 LYS A CA 1 ATOM 2639 C C . LYS A 1 345 ? 40.159 65.012 25.294 1.00 15.31 ? 345 LYS A C 1 ATOM 2640 O O . LYS A 1 345 ? 41.284 64.813 25.714 1.00 20.06 ? 345 LYS A O 1 ATOM 2641 C CB . LYS A 1 345 ? 39.156 66.083 23.226 1.00 12.77 ? 345 LYS A CB 1 ATOM 2642 C CG . LYS A 1 345 ? 40.064 67.305 23.308 1.00 17.41 ? 345 LYS A CG 1 ATOM 2643 C CD . LYS A 1 345 ? 39.304 68.549 22.865 1.00 20.10 ? 345 LYS A CD 1 ATOM 2644 C CE . LYS A 1 345 ? 40.148 69.817 22.925 1.00 21.85 ? 345 LYS A CE 1 ATOM 2645 N NZ . LYS A 1 345 ? 39.186 70.875 22.453 1.00 23.76 ? 345 LYS A NZ 1 ATOM 2646 N N . GLN A 1 346 ? 39.164 65.319 26.103 1.00 15.69 ? 346 GLN A N 1 ATOM 2647 C CA . GLN A 1 346 ? 39.402 65.531 27.530 1.00 15.80 ? 346 GLN A CA 1 ATOM 2648 C C . GLN A 1 346 ? 39.761 64.273 28.329 1.00 15.80 ? 346 GLN A C 1 ATOM 2649 O O . GLN A 1 346 ? 39.190 63.207 28.153 1.00 15.44 ? 346 GLN A O 1 ATOM 2650 C CB . GLN A 1 346 ? 38.152 66.140 28.169 1.00 17.17 ? 346 GLN A CB 1 ATOM 2651 C CG . GLN A 1 346 ? 37.796 67.529 27.683 1.00 18.89 ? 346 GLN A CG 1 ATOM 2652 C CD . GLN A 1 346 ? 36.818 67.556 26.527 1.00 22.39 ? 346 GLN A CD 1 ATOM 2653 O OE1 . GLN A 1 346 ? 36.600 66.558 25.827 1.00 20.24 ? 346 GLN A OE1 1 ATOM 2654 N NE2 . GLN A 1 346 ? 36.224 68.723 26.304 1.00 24.80 ? 346 GLN A NE2 1 ATOM 2655 N N . ASN A 1 347 ? 40.667 64.403 29.295 1.00 17.82 ? 347 ASN A N 1 ATOM 2656 C CA . ASN A 1 347 ? 40.973 63.253 30.148 1.00 18.21 ? 347 ASN A CA 1 ATOM 2657 C C . ASN A 1 347 ? 39.712 62.767 30.866 1.00 17.40 ? 347 ASN A C 1 ATOM 2658 O O . ASN A 1 347 ? 39.502 61.570 31.031 1.00 17.05 ? 347 ASN A O 1 ATOM 2659 C CB . ASN A 1 347 ? 41.998 63.609 31.216 1.00 22.40 ? 347 ASN A CB 1 ATOM 2660 C CG . ASN A 1 347 ? 43.351 63.754 30.649 1.00 25.48 ? 347 ASN A CG 1 ATOM 2661 O OD1 . ASN A 1 347 ? 43.787 62.915 29.844 1.00 25.92 ? 347 ASN A OD1 1 ATOM 2662 N ND2 . ASN A 1 347 ? 44.061 64.833 31.049 1.00 27.05 ? 347 ASN A ND2 1 ATOM 2663 N N . THR A 1 348 ? 38.854 63.701 31.254 1.00 16.15 ? 348 THR A N 1 ATOM 2664 C CA . THR A 1 348 ? 37.637 63.321 31.943 1.00 16.43 ? 348 THR A CA 1 ATOM 2665 C C . THR A 1 348 ? 36.705 62.568 31.002 1.00 14.04 ? 348 THR A C 1 ATOM 2666 O O . THR A 1 348 ? 35.878 61.803 31.471 1.00 13.36 ? 348 THR A O 1 ATOM 2667 C CB . THR A 1 348 ? 36.898 64.566 32.508 1.00 18.36 ? 348 THR A CB 1 ATOM 2668 O OG1 . THR A 1 348 ? 36.745 65.551 31.467 1.00 21.01 ? 348 THR A OG1 1 ATOM 2669 C CG2 . THR A 1 348 ? 37.678 65.147 33.695 1.00 19.39 ? 348 THR A CG2 1 ATOM 2670 N N . GLU A 1 349 ? 36.805 62.810 29.686 1.00 13.52 ? 349 GLU A N 1 ATOM 2671 C CA . GLU A 1 349 ? 35.970 62.130 28.688 1.00 10.84 ? 349 GLU A CA 1 ATOM 2672 C C . GLU A 1 349 ? 36.413 60.661 28.557 1.00 10.50 ? 349 GLU A C 1 ATOM 2673 O O . GLU A 1 349 ? 35.587 59.788 28.473 1.00 10.69 ? 349 GLU A O 1 ATOM 2674 C CB . GLU A 1 349 ? 36.093 62.826 27.326 1.00 12.78 ? 349 GLU A CB 1 ATOM 2675 C CG . GLU A 1 349 ? 35.292 62.089 26.250 1.00 13.33 ? 349 GLU A CG 1 ATOM 2676 C CD . GLU A 1 349 ? 35.493 62.660 24.884 1.00 14.50 ? 349 GLU A CD 1 ATOM 2677 O OE1 . GLU A 1 349 ? 36.197 63.680 24.789 1.00 13.36 ? 349 GLU A OE1 1 ATOM 2678 O OE2 . GLU A 1 349 ? 34.930 62.106 23.900 1.00 14.56 ? 349 GLU A OE2 1 ATOM 2679 N N . TRP A 1 350 ? 37.718 60.419 28.522 1.00 10.87 ? 350 TRP A N 1 ATOM 2680 C CA . TRP A 1 350 ? 38.234 59.058 28.505 1.00 11.81 ? 350 TRP A CA 1 ATOM 2681 C C . TRP A 1 350 ? 37.722 58.320 29.716 1.00 12.21 ? 350 TRP A C 1 ATOM 2682 O O . TRP A 1 350 ? 37.216 57.203 29.604 1.00 12.34 ? 350 TRP A O 1 ATOM 2683 C CB . TRP A 1 350 ? 39.781 59.034 28.542 1.00 10.85 ? 350 TRP A CB 1 ATOM 2684 C CG . TRP A 1 350 ? 40.446 59.276 27.177 1.00 12.38 ? 350 TRP A CG 1 ATOM 2685 C CD1 . TRP A 1 350 ? 40.813 60.494 26.619 1.00 11.97 ? 350 TRP A CD1 1 ATOM 2686 C CD2 . TRP A 1 350 ? 40.753 58.277 26.202 1.00 12.49 ? 350 TRP A CD2 1 ATOM 2687 N NE1 . TRP A 1 350 ? 41.338 60.302 25.339 1.00 13.43 ? 350 TRP A NE1 1 ATOM 2688 C CE2 . TRP A 1 350 ? 41.300 58.957 25.056 1.00 11.83 ? 350 TRP A CE2 1 ATOM 2689 C CE3 . TRP A 1 350 ? 40.612 56.875 26.154 1.00 13.03 ? 350 TRP A CE3 1 ATOM 2690 C CZ2 . TRP A 1 350 ? 41.694 58.267 23.900 1.00 13.49 ? 350 TRP A CZ2 1 ATOM 2691 C CZ3 . TRP A 1 350 ? 40.996 56.208 24.989 1.00 13.48 ? 350 TRP A CZ3 1 ATOM 2692 C CH2 . TRP A 1 350 ? 41.528 56.906 23.885 1.00 13.80 ? 350 TRP A CH2 1 ATOM 2693 N N . ASP A 1 351 ? 37.824 58.939 30.890 1.00 14.53 ? 351 ASP A N 1 ATOM 2694 C CA . ASP A 1 351 ? 37.344 58.276 32.079 1.00 13.73 ? 351 ASP A CA 1 ATOM 2695 C C . ASP A 1 351 ? 35.847 58.025 32.105 1.00 13.46 ? 351 ASP A C 1 ATOM 2696 O O . ASP A 1 351 ? 35.434 56.923 32.460 1.00 12.78 ? 351 ASP A O 1 ATOM 2697 C CB . ASP A 1 351 ? 37.685 59.058 33.346 1.00 15.00 ? 351 ASP A CB 1 ATOM 2698 C CG . ASP A 1 351 ? 39.147 59.140 33.594 1.00 18.93 ? 351 ASP A CG 1 ATOM 2699 O OD1 . ASP A 1 351 ? 39.820 58.088 33.527 1.00 21.32 ? 351 ASP A OD1 1 ATOM 2700 O OD2 . ASP A 1 351 ? 39.595 60.260 33.901 1.00 26.13 ? 351 ASP A OD2 1 ATOM 2701 N N . VAL A 1 352 ? 35.048 58.989 31.674 1.00 12.57 ? 352 VAL A N 1 ATOM 2702 C CA . VAL A 1 352 ? 33.612 58.785 31.781 1.00 14.45 ? 352 VAL A CA 1 ATOM 2703 C C . VAL A 1 352 ? 33.157 57.680 30.820 1.00 13.82 ? 352 VAL A C 1 ATOM 2704 O O . VAL A 1 352 ? 32.217 56.952 31.101 1.00 15.31 ? 352 VAL A O 1 ATOM 2705 C CB . VAL A 1 352 ? 32.824 60.162 31.610 1.00 15.56 ? 352 VAL A CB 1 ATOM 2706 C CG1 . VAL A 1 352 ? 32.658 60.561 30.181 1.00 15.64 ? 352 VAL A CG1 1 ATOM 2707 C CG2 . VAL A 1 352 ? 31.495 60.099 32.329 1.00 18.38 ? 352 VAL A CG2 1 ATOM 2708 N N . GLN A 1 353 ? 33.768 57.594 29.633 1.00 13.12 ? 353 GLN A N 1 ATOM 2709 C CA . GLN A 1 353 ? 33.363 56.535 28.701 1.00 11.92 ? 353 GLN A CA 1 ATOM 2710 C C . GLN A 1 353 ? 33.902 55.201 29.184 1.00 12.93 ? 353 GLN A C 1 ATOM 2711 O O . GLN A 1 353 ? 33.167 54.227 29.267 1.00 12.15 ? 353 GLN A O 1 ATOM 2712 C CB . GLN A 1 353 ? 33.859 56.849 27.236 1.00 10.90 ? 353 GLN A CB 1 ATOM 2713 C CG . GLN A 1 353 ? 33.318 58.148 26.636 1.00 12.40 ? 353 GLN A CG 1 ATOM 2714 C CD . GLN A 1 353 ? 31.838 58.094 26.178 1.00 12.91 ? 353 GLN A CD 1 ATOM 2715 O OE1 . GLN A 1 353 ? 31.027 57.376 26.758 1.00 13.02 ? 353 GLN A OE1 1 ATOM 2716 N NE2 . GLN A 1 353 ? 31.480 58.871 25.165 1.00 13.51 ? 353 GLN A NE2 1 ATOM 2717 N N . ARG A 1 354 ? 35.183 55.145 29.512 1.00 12.86 ? 354 ARG A N 1 ATOM 2718 C CA . ARG A 1 354 ? 35.767 53.879 29.929 1.00 11.78 ? 354 ARG A CA 1 ATOM 2719 C C . ARG A 1 354 ? 35.125 53.261 31.171 1.00 14.57 ? 354 ARG A C 1 ATOM 2720 O O . ARG A 1 354 ? 34.744 52.094 31.168 1.00 13.31 ? 354 ARG A O 1 ATOM 2721 C CB . ARG A 1 354 ? 37.258 54.056 30.191 1.00 12.37 ? 354 ARG A CB 1 ATOM 2722 C CG . ARG A 1 354 ? 37.941 52.697 30.597 1.00 13.33 ? 354 ARG A CG 1 ATOM 2723 C CD . ARG A 1 354 ? 39.486 52.891 30.840 1.00 14.93 ? 354 ARG A CD 1 ATOM 2724 N NE . ARG A 1 354 ? 39.796 53.862 31.891 1.00 13.41 ? 354 ARG A NE 1 ATOM 2725 C CZ . ARG A 1 354 ? 39.623 53.652 33.196 1.00 14.46 ? 354 ARG A CZ 1 ATOM 2726 N NH1 . ARG A 1 354 ? 39.125 52.492 33.640 1.00 14.35 ? 354 ARG A NH1 1 ATOM 2727 N NH2 . ARG A 1 354 ? 39.979 54.603 34.058 1.00 16.62 ? 354 ARG A NH2 1 ATOM 2728 N N . VAL A 1 355 ? 35.011 54.041 32.248 1.00 12.54 ? 355 VAL A N 1 ATOM 2729 C CA . VAL A 1 355 ? 34.449 53.493 33.453 1.00 12.08 ? 355 VAL A CA 1 ATOM 2730 C C . VAL A 1 355 ? 32.983 53.050 33.378 1.00 12.07 ? 355 VAL A C 1 ATOM 2731 O O . VAL A 1 355 ? 32.657 52.011 33.945 1.00 12.24 ? 355 VAL A O 1 ATOM 2732 C CB . VAL A 1 355 ? 34.682 54.502 34.591 1.00 14.87 ? 355 VAL A CB 1 ATOM 2733 C CG1 . VAL A 1 355 ? 34.083 53.997 35.918 1.00 18.97 ? 355 VAL A CG1 1 ATOM 2734 C CG2 . VAL A 1 355 ? 36.184 54.710 34.740 1.00 16.91 ? 355 VAL A CG2 1 ATOM 2735 N N . ASN A 1 356 ? 32.127 53.797 32.681 1.00 12.08 ? 356 ASN A N 1 ATOM 2736 C CA . ASN A 1 356 ? 30.722 53.426 32.620 1.00 13.53 ? 356 ASN A CA 1 ATOM 2737 C C . ASN A 1 356 ? 30.618 52.204 31.754 1.00 13.03 ? 356 ASN A C 1 ATOM 2738 O O . ASN A 1 356 ? 29.843 51.291 32.042 1.00 12.92 ? 356 ASN A O 1 ATOM 2739 C CB . ASN A 1 356 ? 29.899 54.622 32.148 1.00 13.04 ? 356 ASN A CB 1 ATOM 2740 C CG . ASN A 1 356 ? 29.711 55.626 33.268 1.00 15.91 ? 356 ASN A CG 1 ATOM 2741 O OD1 . ASN A 1 356 ? 29.121 55.284 34.316 1.00 14.45 ? 356 ASN A OD1 1 ATOM 2742 N ND2 . ASN A 1 356 ? 30.216 56.864 33.087 1.00 14.63 ? 356 ASN A ND2 1 ATOM 2743 N N . TYR A 1 357 ? 31.428 52.120 30.704 1.00 12.85 ? 357 TYR A N 1 ATOM 2744 C CA . TYR A 1 357 ? 31.314 50.900 29.889 1.00 11.85 ? 357 TYR A CA 1 ATOM 2745 C C . TYR A 1 357 ? 31.889 49.704 30.633 1.00 13.75 ? 357 TYR A C 1 ATOM 2746 O O . TYR A 1 357 ? 31.347 48.584 30.550 1.00 13.15 ? 357 TYR A O 1 ATOM 2747 C CB . TYR A 1 357 ? 31.963 51.117 28.508 1.00 12.13 ? 357 TYR A CB 1 ATOM 2748 C CG . TYR A 1 357 ? 30.950 51.649 27.502 1.00 10.21 ? 357 TYR A CG 1 ATOM 2749 C CD1 . TYR A 1 357 ? 30.174 50.736 26.790 1.00 12.03 ? 357 TYR A CD1 1 ATOM 2750 C CD2 . TYR A 1 357 ? 30.718 53.007 27.322 1.00 10.90 ? 357 TYR A CD2 1 ATOM 2751 C CE1 . TYR A 1 357 ? 29.192 51.173 25.943 1.00 10.94 ? 357 TYR A CE1 1 ATOM 2752 C CE2 . TYR A 1 357 ? 29.750 53.430 26.478 1.00 9.98 ? 357 TYR A CE2 1 ATOM 2753 C CZ . TYR A 1 357 ? 28.986 52.518 25.799 1.00 10.37 ? 357 TYR A CZ 1 ATOM 2754 O OH . TYR A 1 357 ? 28.007 52.929 24.925 1.00 10.94 ? 357 TYR A OH 1 ATOM 2755 N N . GLU A 1 358 ? 32.957 49.887 31.414 1.00 13.21 ? 358 GLU A N 1 ATOM 2756 C CA . GLU A 1 358 ? 33.441 48.723 32.144 1.00 13.18 ? 358 GLU A CA 1 ATOM 2757 C C . GLU A 1 358 ? 32.444 48.229 33.182 1.00 13.75 ? 358 GLU A C 1 ATOM 2758 O O . GLU A 1 358 ? 32.394 47.027 33.402 1.00 13.56 ? 358 GLU A O 1 ATOM 2759 C CB . GLU A 1 358 ? 34.786 49.017 32.774 1.00 14.25 ? 358 GLU A CB 1 ATOM 2760 C CG . GLU A 1 358 ? 35.748 49.211 31.618 1.00 17.66 ? 358 GLU A CG 1 ATOM 2761 C CD . GLU A 1 358 ? 37.179 49.475 31.987 1.00 20.29 ? 358 GLU A CD 1 ATOM 2762 O OE1 . GLU A 1 358 ? 37.455 49.970 33.063 1.00 20.44 ? 358 GLU A OE1 1 ATOM 2763 O OE2 . GLU A 1 358 ? 38.075 49.230 31.126 1.00 24.28 ? 358 GLU A OE2 1 ATOM 2764 N N . ARG A 1 359 ? 31.626 49.118 33.768 1.00 13.20 ? 359 ARG A N 1 ATOM 2765 C CA . ARG A 1 359 ? 30.604 48.629 34.732 1.00 13.84 ? 359 ARG A CA 1 ATOM 2766 C C . ARG A 1 359 ? 29.531 47.819 33.950 1.00 12.25 ? 359 ARG A C 1 ATOM 2767 O O . ARG A 1 359 ? 29.080 46.759 34.420 1.00 15.34 ? 359 ARG A O 1 ATOM 2768 C CB . ARG A 1 359 ? 29.930 49.797 35.501 1.00 17.43 ? 359 ARG A CB 1 ATOM 2769 C CG . ARG A 1 359 ? 30.782 50.443 36.567 1.00 21.19 ? 359 ARG A CG 1 ATOM 2770 C CD . ARG A 1 359 ? 30.070 51.696 37.136 1.00 25.04 ? 359 ARG A CD 1 ATOM 2771 N NE . ARG A 1 359 ? 31.039 52.559 37.824 1.00 27.21 ? 359 ARG A NE 1 ATOM 2772 C CZ . ARG A 1 359 ? 31.144 53.887 37.667 1.00 28.43 ? 359 ARG A CZ 1 ATOM 2773 N NH1 . ARG A 1 359 ? 30.328 54.579 36.841 1.00 26.94 ? 359 ARG A NH1 1 ATOM 2774 N NH2 . ARG A 1 359 ? 32.119 54.519 38.321 1.00 30.75 ? 359 ARG A NH2 1 ATOM 2775 N N . LEU A 1 360 ? 29.142 48.309 32.756 1.00 12.42 ? 360 LEU A N 1 ATOM 2776 C CA . LEU A 1 360 ? 28.129 47.629 31.972 1.00 10.72 ? 360 LEU A CA 1 ATOM 2777 C C . LEU A 1 360 ? 28.710 46.280 31.581 1.00 11.70 ? 360 LEU A C 1 ATOM 2778 O O . LEU A 1 360 ? 28.027 45.277 31.689 1.00 13.61 ? 360 LEU A O 1 ATOM 2779 C CB . LEU A 1 360 ? 27.744 48.453 30.752 1.00 13.85 ? 360 LEU A CB 1 ATOM 2780 C CG . LEU A 1 360 ? 26.902 49.690 31.129 1.00 13.96 ? 360 LEU A CG 1 ATOM 2781 C CD1 . LEU A 1 360 ? 26.933 50.734 30.076 1.00 15.76 ? 360 LEU A CD1 1 ATOM 2782 C CD2 . LEU A 1 360 ? 25.440 49.232 31.414 1.00 16.69 ? 360 LEU A CD2 1 ATOM 2783 N N . PHE A 1 361 ? 29.970 46.198 31.119 1.00 10.71 ? 361 PHE A N 1 ATOM 2784 C CA . PHE A 1 361 ? 30.534 44.874 30.773 1.00 12.79 ? 361 PHE A CA 1 ATOM 2785 C C . PHE A 1 361 ? 30.623 43.921 31.945 1.00 13.42 ? 361 PHE A C 1 ATOM 2786 O O . PHE A 1 361 ? 30.342 42.738 31.808 1.00 13.81 ? 361 PHE A O 1 ATOM 2787 C CB . PHE A 1 361 ? 31.990 44.956 30.211 1.00 11.00 ? 361 PHE A CB 1 ATOM 2788 C CG . PHE A 1 361 ? 32.158 45.797 28.958 1.00 12.32 ? 361 PHE A CG 1 ATOM 2789 C CD1 . PHE A 1 361 ? 31.108 46.006 28.075 1.00 11.37 ? 361 PHE A CD1 1 ATOM 2790 C CD2 . PHE A 1 361 ? 33.398 46.396 28.692 1.00 11.62 ? 361 PHE A CD2 1 ATOM 2791 C CE1 . PHE A 1 361 ? 31.271 46.810 26.929 1.00 13.27 ? 361 PHE A CE1 1 ATOM 2792 C CE2 . PHE A 1 361 ? 33.559 47.196 27.559 1.00 14.32 ? 361 PHE A CE2 1 ATOM 2793 C CZ . PHE A 1 361 ? 32.510 47.404 26.688 1.00 12.44 ? 361 PHE A CZ 1 ATOM 2794 N N . GLU A 1 362 ? 31.090 44.397 33.104 1.00 13.64 ? 362 GLU A N 1 ATOM 2795 C CA . GLU A 1 362 ? 31.184 43.456 34.233 1.00 14.45 ? 362 GLU A CA 1 ATOM 2796 C C . GLU A 1 362 ? 29.800 42.875 34.583 1.00 12.44 ? 362 GLU A C 1 ATOM 2797 O O . GLU A 1 362 ? 29.692 41.692 34.837 1.00 14.52 ? 362 GLU A O 1 ATOM 2798 C CB . GLU A 1 362 ? 31.757 44.087 35.511 1.00 16.28 ? 362 GLU A CB 1 ATOM 2799 C CG . GLU A 1 362 ? 31.998 43.001 36.630 1.00 19.81 ? 362 GLU A CG 1 ATOM 2800 C CD . GLU A 1 362 ? 32.426 43.614 37.971 1.00 23.43 ? 362 GLU A CD 1 ATOM 2801 O OE1 . GLU A 1 362 ? 32.871 44.779 37.959 1.00 24.45 ? 362 GLU A OE1 1 ATOM 2802 O OE2 . GLU A 1 362 ? 32.314 42.931 39.025 1.00 21.71 ? 362 GLU A OE2 1 ATOM 2803 N N . HIS A 1 363 ? 28.754 43.681 34.578 1.00 14.63 ? 363 HIS A N 1 ATOM 2804 C CA . HIS A 1 363 ? 27.428 43.142 34.896 1.00 15.24 ? 363 HIS A CA 1 ATOM 2805 C C . HIS A 1 363 ? 26.951 42.203 33.744 1.00 14.68 ? 363 HIS A C 1 ATOM 2806 O O . HIS A 1 363 ? 26.595 41.024 33.998 1.00 13.83 ? 363 HIS A O 1 ATOM 2807 C CB . HIS A 1 363 ? 26.425 44.278 35.143 1.00 17.82 ? 363 HIS A CB 1 ATOM 2808 C CG . HIS A 1 363 ? 25.005 43.822 35.334 1.00 18.45 ? 363 HIS A CG 1 ATOM 2809 N ND1 . HIS A 1 363 ? 24.556 43.269 36.516 1.00 20.15 ? 363 HIS A ND1 1 ATOM 2810 C CD2 . HIS A 1 363 ? 23.949 43.798 34.481 1.00 20.62 ? 363 HIS A CD2 1 ATOM 2811 C CE1 . HIS A 1 363 ? 23.288 42.921 36.388 1.00 18.78 ? 363 HIS A CE1 1 ATOM 2812 N NE2 . HIS A 1 363 ? 22.891 43.231 35.164 1.00 21.88 ? 363 HIS A NE2 1 ATOM 2813 N N . ILE A 1 364 ? 26.900 42.686 32.508 1.00 13.85 ? 364 ILE A N 1 ATOM 2814 C CA . ILE A 1 364 ? 26.416 41.869 31.384 1.00 14.50 ? 364 ILE A CA 1 ATOM 2815 C C . ILE A 1 364 ? 27.158 40.569 31.254 1.00 12.52 ? 364 ILE A C 1 ATOM 2816 O O . ILE A 1 364 ? 26.554 39.490 31.135 1.00 14.03 ? 364 ILE A O 1 ATOM 2817 C CB . ILE A 1 364 ? 26.541 42.626 30.057 1.00 14.06 ? 364 ILE A CB 1 ATOM 2818 C CG1 . ILE A 1 364 ? 25.626 43.853 30.107 1.00 14.37 ? 364 ILE A CG1 1 ATOM 2819 C CG2 . ILE A 1 364 ? 26.267 41.654 28.840 1.00 13.69 ? 364 ILE A CG2 1 ATOM 2820 C CD1 . ILE A 1 364 ? 25.928 44.913 29.058 1.00 13.15 ? 364 ILE A CD1 1 ATOM 2821 N N . ASN A 1 365 ? 28.459 40.615 31.336 1.00 12.43 ? 365 ASN A N 1 ATOM 2822 C CA . ASN A 1 365 ? 29.224 39.386 31.152 1.00 13.66 ? 365 ASN A CA 1 ATOM 2823 C C . ASN A 1 365 ? 29.028 38.329 32.230 1.00 16.17 ? 365 ASN A C 1 ATOM 2824 O O . ASN A 1 365 ? 29.269 37.153 31.965 1.00 16.40 ? 365 ASN A O 1 ATOM 2825 C CB . ASN A 1 365 ? 30.711 39.700 30.964 1.00 13.65 ? 365 ASN A CB 1 ATOM 2826 C CG . ASN A 1 365 ? 30.973 40.504 29.628 1.00 11.15 ? 365 ASN A CG 1 ATOM 2827 O OD1 . ASN A 1 365 ? 30.075 40.699 28.791 1.00 13.77 ? 365 ASN A OD1 1 ATOM 2828 N ND2 . ASN A 1 365 ? 32.177 41.010 29.494 1.00 11.24 ? 365 ASN A ND2 1 ATOM 2829 N N . SER A 1 366 ? 28.536 38.777 33.391 1.00 18.44 ? 366 SER A N 1 ATOM 2830 C CA . SER A 1 366 ? 28.299 37.916 34.559 1.00 19.58 ? 366 SER A CA 1 ATOM 2831 C C . SER A 1 366 ? 26.867 37.411 34.672 1.00 21.24 ? 366 SER A C 1 ATOM 2832 O O . SER A 1 366 ? 26.576 36.526 35.477 1.00 22.91 ? 366 SER A O 1 ATOM 2833 C CB . SER A 1 366 ? 28.680 38.694 35.851 1.00 20.25 ? 366 SER A CB 1 ATOM 2834 O OG . SER A 1 366 ? 27.778 39.783 36.096 1.00 20.22 ? 366 SER A OG 1 ATOM 2835 N N . GLN A 1 367 ? 25.972 37.950 33.854 1.00 21.60 ? 367 GLN A N 1 ATOM 2836 C CA . GLN A 1 367 ? 24.571 37.573 33.871 1.00 23.11 ? 367 GLN A CA 1 ATOM 2837 C C . GLN A 1 367 ? 24.361 36.619 32.715 1.00 22.40 ? 367 GLN A C 1 ATOM 2838 O O . GLN A 1 367 ? 24.148 37.028 31.551 1.00 21.24 ? 367 GLN A O 1 ATOM 2839 C CB . GLN A 1 367 ? 23.690 38.803 33.698 1.00 24.28 ? 367 GLN A CB 1 ATOM 2840 C CG . GLN A 1 367 ? 23.600 39.671 34.929 1.00 29.40 ? 367 GLN A CG 1 ATOM 2841 C CD . GLN A 1 367 ? 23.032 38.878 36.076 1.00 31.70 ? 367 GLN A CD 1 ATOM 2842 O OE1 . GLN A 1 367 ? 23.796 38.752 37.150 1.00 34.66 ? 367 GLN A OE1 1 ATOM 2843 N NE2 . GLN A 1 367 ? 21.932 38.343 35.976 1.00 33.76 ? 367 GLN A NE2 1 ATOM 2844 N N . ALA A 1 368 ? 24.420 35.331 33.038 1.00 21.83 ? 368 ALA A N 1 ATOM 2845 C CA . ALA A 1 368 ? 24.256 34.257 32.051 1.00 20.72 ? 368 ALA A CA 1 ATOM 2846 C C . ALA A 1 368 ? 23.020 34.381 31.144 1.00 21.02 ? 368 ALA A C 1 ATOM 2847 O O . ALA A 1 368 ? 23.091 34.008 29.975 1.00 20.63 ? 368 ALA A O 1 ATOM 2848 C CB . ALA A 1 368 ? 24.232 32.873 32.771 1.00 21.16 ? 368 ALA A CB 1 ATOM 2849 N N . HIS A 1 369 ? 21.895 34.879 31.667 1.00 19.85 ? 369 HIS A N 1 ATOM 2850 C CA . HIS A 1 369 ? 20.699 34.991 30.853 1.00 20.36 ? 369 HIS A CA 1 ATOM 2851 C C . HIS A 1 369 ? 20.811 35.936 29.636 1.00 20.21 ? 369 HIS A C 1 ATOM 2852 O O . HIS A 1 369 ? 19.942 35.933 28.753 1.00 20.61 ? 369 HIS A O 1 ATOM 2853 C CB . HIS A 1 369 ? 19.508 35.416 31.728 1.00 22.41 ? 369 HIS A CB 1 ATOM 2854 C CG . HIS A 1 369 ? 19.646 36.786 32.316 1.00 23.83 ? 369 HIS A CG 1 ATOM 2855 N ND1 . HIS A 1 369 ? 19.182 37.925 31.686 1.00 25.42 ? 369 HIS A ND1 1 ATOM 2856 C CD2 . HIS A 1 369 ? 20.238 37.200 33.458 1.00 23.51 ? 369 HIS A CD2 1 ATOM 2857 C CE1 . HIS A 1 369 ? 19.493 38.983 32.412 1.00 24.93 ? 369 HIS A CE1 1 ATOM 2858 N NE2 . HIS A 1 369 ? 20.136 38.572 33.493 1.00 25.72 ? 369 HIS A NE2 1 ATOM 2859 N N . PHE A 1 370 ? 21.871 36.750 29.573 1.00 19.74 ? 370 PHE A N 1 ATOM 2860 C CA . PHE A 1 370 ? 22.018 37.624 28.391 1.00 18.55 ? 370 PHE A CA 1 ATOM 2861 C C . PHE A 1 370 ? 22.751 36.867 27.300 1.00 14.63 ? 370 PHE A C 1 ATOM 2862 O O . PHE A 1 370 ? 22.574 37.177 26.120 1.00 15.97 ? 370 PHE A O 1 ATOM 2863 C CB . PHE A 1 370 ? 22.868 38.865 28.676 1.00 18.04 ? 370 PHE A CB 1 ATOM 2864 C CG . PHE A 1 370 ? 22.185 39.906 29.500 1.00 18.75 ? 370 PHE A CG 1 ATOM 2865 C CD1 . PHE A 1 370 ? 20.916 40.413 29.143 1.00 20.80 ? 370 PHE A CD1 1 ATOM 2866 C CD2 . PHE A 1 370 ? 22.824 40.428 30.613 1.00 19.22 ? 370 PHE A CD2 1 ATOM 2867 C CE1 . PHE A 1 370 ? 20.314 41.427 29.891 1.00 22.77 ? 370 PHE A CE1 1 ATOM 2868 C CE2 . PHE A 1 370 ? 22.237 41.435 31.361 1.00 19.70 ? 370 PHE A CE2 1 ATOM 2869 C CZ . PHE A 1 370 ? 20.999 41.934 31.013 1.00 20.48 ? 370 PHE A CZ 1 ATOM 2870 N N . ASN A 1 371 ? 23.560 35.904 27.714 1.00 15.56 ? 371 ASN A N 1 ATOM 2871 C CA . ASN A 1 371 ? 24.385 35.111 26.845 1.00 13.93 ? 371 ASN A CA 1 ATOM 2872 C C . ASN A 1 371 ? 25.189 36.034 25.928 1.00 13.70 ? 371 ASN A C 1 ATOM 2873 O O . ASN A 1 371 ? 25.212 35.841 24.723 1.00 12.98 ? 371 ASN A O 1 ATOM 2874 C CB . ASN A 1 371 ? 23.538 34.122 26.031 1.00 16.13 ? 371 ASN A CB 1 ATOM 2875 C CG . ASN A 1 371 ? 22.858 33.111 26.952 1.00 14.73 ? 371 ASN A CG 1 ATOM 2876 O OD1 . ASN A 1 371 ? 23.539 32.283 27.553 1.00 17.68 ? 371 ASN A OD1 1 ATOM 2877 N ND2 . ASN A 1 371 ? 21.541 33.231 27.100 1.00 15.49 ? 371 ASN A ND2 1 ATOM 2878 N N . VAL A 1 372 ? 25.812 37.049 26.524 1.00 12.37 ? 372 VAL A N 1 ATOM 2879 C CA . VAL A 1 372 ? 26.649 38.035 25.809 1.00 12.88 ? 372 VAL A CA 1 ATOM 2880 C C . VAL A 1 372 ? 28.034 38.091 26.396 1.00 12.92 ? 372 VAL A C 1 ATOM 2881 O O . VAL A 1 372 ? 28.199 37.914 27.600 1.00 13.36 ? 372 VAL A O 1 ATOM 2882 C CB . VAL A 1 372 ? 25.998 39.429 25.932 1.00 13.48 ? 372 VAL A CB 1 ATOM 2883 C CG1 . VAL A 1 372 ? 26.953 40.544 25.430 1.00 14.17 ? 372 VAL A CG1 1 ATOM 2884 C CG2 . VAL A 1 372 ? 24.681 39.422 25.099 1.00 13.86 ? 372 VAL A CG2 1 ATOM 2885 N N . GLN A 1 373 ? 29.074 38.289 25.585 1.00 11.49 ? 373 GLN A N 1 ATOM 2886 C CA . GLN A 1 373 ? 30.420 38.524 26.126 1.00 13.09 ? 373 GLN A CA 1 ATOM 2887 C C . GLN A 1 373 ? 30.825 39.849 25.417 1.00 11.38 ? 373 GLN A C 1 ATOM 2888 O O . GLN A 1 373 ? 31.097 39.862 24.186 1.00 12.41 ? 373 GLN A O 1 ATOM 2889 C CB . GLN A 1 373 ? 31.381 37.386 25.736 1.00 11.51 ? 373 GLN A CB 1 ATOM 2890 C CG . GLN A 1 373 ? 32.883 37.611 26.118 1.00 15.31 ? 373 GLN A CG 1 ATOM 2891 C CD . GLN A 1 373 ? 33.108 37.954 27.608 1.00 15.99 ? 373 GLN A CD 1 ATOM 2892 O OE1 . GLN A 1 373 ? 32.412 37.454 28.499 1.00 19.68 ? 373 GLN A OE1 1 ATOM 2893 N NE2 . GLN A 1 373 ? 34.108 38.811 27.871 1.00 15.02 ? 373 GLN A NE2 1 ATOM 2894 N N . ALA A 1 374 ? 30.865 40.956 26.160 1.00 11.01 ? 374 ALA A N 1 ATOM 2895 C CA . ALA A 1 374 ? 31.192 42.260 25.610 1.00 9.25 ? 374 ALA A CA 1 ATOM 2896 C C . ALA A 1 374 ? 32.496 42.790 26.109 1.00 10.81 ? 374 ALA A C 1 ATOM 2897 O O . ALA A 1 374 ? 32.857 42.575 27.287 1.00 10.95 ? 374 ALA A O 1 ATOM 2898 C CB . ALA A 1 374 ? 30.084 43.230 25.952 1.00 10.57 ? 374 ALA A CB 1 ATOM 2899 N N . GLN A 1 375 ? 33.251 43.435 25.208 1.00 10.28 ? 375 GLN A N 1 ATOM 2900 C CA . GLN A 1 375 ? 34.571 43.978 25.622 1.00 11.66 ? 375 GLN A CA 1 ATOM 2901 C C . GLN A 1 375 ? 34.981 45.066 24.636 1.00 11.57 ? 375 GLN A C 1 ATOM 2902 O O . GLN A 1 375 ? 34.397 45.150 23.525 1.00 10.93 ? 375 GLN A O 1 ATOM 2903 C CB . GLN A 1 375 ? 35.670 42.890 25.539 1.00 13.49 ? 375 GLN A CB 1 ATOM 2904 C CG . GLN A 1 375 ? 35.641 42.204 24.159 1.00 15.90 ? 375 GLN A CG 1 ATOM 2905 C CD . GLN A 1 375 ? 34.851 40.899 24.251 1.00 21.31 ? 375 GLN A CD 1 ATOM 2906 O OE1 . GLN A 1 375 ? 35.253 39.984 24.997 1.00 21.30 ? 375 GLN A OE1 1 ATOM 2907 N NE2 . GLN A 1 375 ? 33.715 40.803 23.518 1.00 20.94 ? 375 GLN A NE2 1 ATOM 2908 N N . PHE A 1 376 ? 35.938 45.911 25.027 1.00 10.56 ? 376 PHE A N 1 ATOM 2909 C CA . PHE A 1 376 ? 36.495 46.892 24.074 1.00 10.46 ? 376 PHE A CA 1 ATOM 2910 C C . PHE A 1 376 ? 37.293 46.089 23.047 1.00 12.40 ? 376 PHE A C 1 ATOM 2911 O O . PHE A 1 376 ? 37.926 45.060 23.403 1.00 14.08 ? 376 PHE A O 1 ATOM 2912 C CB . PHE A 1 376 ? 37.471 47.838 24.795 1.00 10.02 ? 376 PHE A CB 1 ATOM 2913 C CG . PHE A 1 376 ? 36.809 48.739 25.730 1.00 11.45 ? 376 PHE A CG 1 ATOM 2914 C CD1 . PHE A 1 376 ? 35.802 49.563 25.304 1.00 10.17 ? 376 PHE A CD1 1 ATOM 2915 C CD2 . PHE A 1 376 ? 37.192 48.736 27.075 1.00 10.02 ? 376 PHE A CD2 1 ATOM 2916 C CE1 . PHE A 1 376 ? 35.149 50.432 26.238 1.00 12.60 ? 376 PHE A CE1 1 ATOM 2917 C CE2 . PHE A 1 376 ? 36.550 49.590 27.992 1.00 11.81 ? 376 PHE A CE2 1 ATOM 2918 C CZ . PHE A 1 376 ? 35.538 50.433 27.577 1.00 10.94 ? 376 PHE A CZ 1 ATOM 2919 N N . GLY A 1 377 ? 37.291 46.553 21.803 1.00 11.25 ? 377 GLY A N 1 ATOM 2920 C CA . GLY A 1 377 ? 38.063 45.842 20.788 1.00 11.00 ? 377 GLY A CA 1 ATOM 2921 C C . GLY A 1 377 ? 38.530 46.808 19.738 1.00 10.98 ? 377 GLY A C 1 ATOM 2922 O O . GLY A 1 377 ? 38.222 48.025 19.835 1.00 10.98 ? 377 GLY A O 1 ATOM 2923 N N . THR A 1 378 ? 39.239 46.252 18.745 1.00 11.24 ? 378 THR A N 1 ATOM 2924 C CA . THR A 1 378 ? 39.723 47.002 17.605 1.00 11.78 ? 378 THR A CA 1 ATOM 2925 C C . THR A 1 378 ? 38.977 46.508 16.395 1.00 9.96 ? 378 THR A C 1 ATOM 2926 O O . THR A 1 378 ? 38.234 45.502 16.456 1.00 10.37 ? 378 THR A O 1 ATOM 2927 C CB . THR A 1 378 ? 41.243 46.874 17.362 1.00 10.95 ? 378 THR A CB 1 ATOM 2928 O OG1 . THR A 1 378 ? 41.564 45.538 16.978 1.00 12.13 ? 378 THR A OG1 1 ATOM 2929 C CG2 . THR A 1 378 ? 42.039 47.335 18.588 1.00 12.73 ? 378 THR A CG2 1 ATOM 2930 N N . LEU A 1 379 ? 39.131 47.202 15.283 1.00 9.29 ? 379 LEU A N 1 ATOM 2931 C CA . LEU A 1 379 ? 38.466 46.830 14.037 1.00 9.69 ? 379 LEU A CA 1 ATOM 2932 C C . LEU A 1 379 ? 38.962 45.474 13.535 1.00 8.21 ? 379 LEU A C 1 ATOM 2933 O O . LEU A 1 379 ? 38.160 44.617 13.123 1.00 9.83 ? 379 LEU A O 1 ATOM 2934 C CB . LEU A 1 379 ? 38.683 47.924 12.971 1.00 10.19 ? 379 LEU A CB 1 ATOM 2935 C CG . LEU A 1 379 ? 37.850 47.737 11.687 1.00 9.48 ? 379 LEU A CG 1 ATOM 2936 C CD1 . LEU A 1 379 ? 36.314 47.709 11.932 1.00 7.08 ? 379 LEU A CD1 1 ATOM 2937 C CD2 . LEU A 1 379 ? 38.247 48.914 10.718 1.00 9.77 ? 379 LEU A CD2 1 ATOM 2938 N N . GLN A 1 380 ? 40.285 45.267 13.574 1.00 7.95 ? 380 GLN A N 1 ATOM 2939 C CA . GLN A 1 380 ? 40.822 43.998 13.148 1.00 10.05 ? 380 GLN A CA 1 ATOM 2940 C C . GLN A 1 380 ? 40.317 42.860 14.004 1.00 10.70 ? 380 GLN A C 1 ATOM 2941 O O . GLN A 1 380 ? 40.068 41.768 13.487 1.00 9.45 ? 380 GLN A O 1 ATOM 2942 C CB . GLN A 1 380 ? 42.340 44.015 13.200 1.00 11.96 ? 380 GLN A CB 1 ATOM 2943 C CG . GLN A 1 380 ? 42.985 42.739 12.572 1.00 12.24 ? 380 GLN A CG 1 ATOM 2944 C CD . GLN A 1 380 ? 42.681 42.578 11.089 1.00 16.58 ? 380 GLN A CD 1 ATOM 2945 O OE1 . GLN A 1 380 ? 42.701 43.558 10.320 1.00 15.37 ? 380 GLN A OE1 1 ATOM 2946 N NE2 . GLN A 1 380 ? 42.402 41.338 10.663 1.00 17.42 ? 380 GLN A NE2 1 ATOM 2947 N N . GLU A 1 381 ? 40.173 43.124 15.305 1.00 9.65 ? 381 GLU A N 1 ATOM 2948 C CA . GLU A 1 381 ? 39.677 42.066 16.169 1.00 8.91 ? 381 GLU A CA 1 ATOM 2949 C C . GLU A 1 381 ? 38.251 41.664 15.751 1.00 8.37 ? 381 GLU A C 1 ATOM 2950 O O . GLU A 1 381 ? 37.956 40.452 15.752 1.00 9.06 ? 381 GLU A O 1 ATOM 2951 C CB . GLU A 1 381 ? 39.639 42.491 17.631 1.00 11.13 ? 381 GLU A CB 1 ATOM 2952 C CG . GLU A 1 381 ? 40.948 42.553 18.353 1.00 15.34 ? 381 GLU A CG 1 ATOM 2953 C CD . GLU A 1 381 ? 40.609 42.823 19.828 1.00 20.00 ? 381 GLU A CD 1 ATOM 2954 O OE1 . GLU A 1 381 ? 40.100 41.926 20.562 1.00 24.41 ? 381 GLU A OE1 1 ATOM 2955 O OE2 . GLU A 1 381 ? 40.795 43.944 20.230 1.00 19.69 ? 381 GLU A OE2 1 ATOM 2956 N N . TYR A 1 382 ? 37.419 42.631 15.368 1.00 8.01 ? 382 TYR A N 1 ATOM 2957 C CA . TYR A 1 382 ? 36.083 42.320 14.959 1.00 8.29 ? 382 TYR A CA 1 ATOM 2958 C C . TYR A 1 382 ? 36.124 41.439 13.705 1.00 8.32 ? 382 TYR A C 1 ATOM 2959 O O . TYR A 1 382 ? 35.509 40.335 13.657 1.00 10.93 ? 382 TYR A O 1 ATOM 2960 C CB . TYR A 1 382 ? 35.262 43.609 14.704 1.00 7.43 ? 382 TYR A CB 1 ATOM 2961 C CG . TYR A 1 382 ? 33.985 43.326 13.944 1.00 7.39 ? 382 TYR A CG 1 ATOM 2962 C CD1 . TYR A 1 382 ? 32.890 42.754 14.591 1.00 8.36 ? 382 TYR A CD1 1 ATOM 2963 C CD2 . TYR A 1 382 ? 33.846 43.576 12.563 1.00 6.76 ? 382 TYR A CD2 1 ATOM 2964 C CE1 . TYR A 1 382 ? 31.747 42.444 13.917 1.00 8.60 ? 382 TYR A CE1 1 ATOM 2965 C CE2 . TYR A 1 382 ? 32.675 43.265 11.874 1.00 6.93 ? 382 TYR A CE2 1 ATOM 2966 C CZ . TYR A 1 382 ? 31.623 42.695 12.577 1.00 8.56 ? 382 TYR A CZ 1 ATOM 2967 O OH . TYR A 1 382 ? 30.435 42.358 11.969 1.00 8.38 ? 382 TYR A OH 1 ATOM 2968 N N . PHE A 1 383 ? 36.863 41.891 12.674 1.00 8.84 ? 383 PHE A N 1 ATOM 2969 C CA . PHE A 1 383 ? 36.898 41.108 11.426 1.00 9.11 ? 383 PHE A CA 1 ATOM 2970 C C . PHE A 1 383 ? 37.498 39.717 11.641 1.00 9.25 ? 383 PHE A C 1 ATOM 2971 O O . PHE A 1 383 ? 37.011 38.740 11.044 1.00 11.59 ? 383 PHE A O 1 ATOM 2972 C CB . PHE A 1 383 ? 37.675 41.837 10.306 1.00 8.31 ? 383 PHE A CB 1 ATOM 2973 C CG . PHE A 1 383 ? 36.906 43.030 9.705 1.00 9.05 ? 383 PHE A CG 1 ATOM 2974 C CD1 . PHE A 1 383 ? 35.715 42.816 9.049 1.00 10.40 ? 383 PHE A CD1 1 ATOM 2975 C CD2 . PHE A 1 383 ? 37.412 44.336 9.790 1.00 7.95 ? 383 PHE A CD2 1 ATOM 2976 C CE1 . PHE A 1 383 ? 34.969 43.875 8.432 1.00 9.91 ? 383 PHE A CE1 1 ATOM 2977 C CE2 . PHE A 1 383 ? 36.699 45.401 9.198 1.00 7.45 ? 383 PHE A CE2 1 ATOM 2978 C CZ . PHE A 1 383 ? 35.471 45.168 8.514 1.00 9.24 ? 383 PHE A CZ 1 ATOM 2979 N N . ASP A 1 384 ? 38.544 39.643 12.484 1.00 8.33 ? 384 ASP A N 1 ATOM 2980 C CA . ASP A 1 384 ? 39.142 38.329 12.681 1.00 8.67 ? 384 ASP A CA 1 ATOM 2981 C C . ASP A 1 384 ? 38.064 37.404 13.258 1.00 10.15 ? 384 ASP A C 1 ATOM 2982 O O . ASP A 1 384 ? 37.977 36.209 12.847 1.00 9.62 ? 384 ASP A O 1 ATOM 2983 C CB . ASP A 1 384 ? 40.310 38.407 13.687 1.00 11.67 ? 384 ASP A CB 1 ATOM 2984 C CG . ASP A 1 384 ? 41.559 39.003 13.086 1.00 14.76 ? 384 ASP A CG 1 ATOM 2985 O OD1 . ASP A 1 384 ? 41.689 39.038 11.827 1.00 17.62 ? 384 ASP A OD1 1 ATOM 2986 O OD2 . ASP A 1 384 ? 42.407 39.418 13.902 1.00 19.14 ? 384 ASP A OD2 1 ATOM 2987 N N . ALA A 1 385 ? 37.246 37.916 14.205 1.00 9.01 ? 385 ALA A N 1 ATOM 2988 C CA . ALA A 1 385 ? 36.246 37.038 14.833 1.00 10.30 ? 385 ALA A CA 1 ATOM 2989 C C . ALA A 1 385 ? 35.162 36.643 13.845 1.00 9.80 ? 385 ALA A C 1 ATOM 2990 O O . ALA A 1 385 ? 34.622 35.529 13.883 1.00 11.69 ? 385 ALA A O 1 ATOM 2991 C CB . ALA A 1 385 ? 35.637 37.716 16.058 1.00 10.20 ? 385 ALA A CB 1 ATOM 2992 N N . VAL A 1 386 ? 34.806 37.580 12.963 1.00 10.52 ? 386 VAL A N 1 ATOM 2993 C CA . VAL A 1 386 ? 33.777 37.295 11.969 1.00 9.45 ? 386 VAL A CA 1 ATOM 2994 C C . VAL A 1 386 ? 34.255 36.163 11.051 1.00 12.41 ? 386 VAL A C 1 ATOM 2995 O O . VAL A 1 386 ? 33.517 35.209 10.763 1.00 12.26 ? 386 VAL A O 1 ATOM 2996 C CB . VAL A 1 386 ? 33.509 38.558 11.122 1.00 11.66 ? 386 VAL A CB 1 ATOM 2997 C CG1 . VAL A 1 386 ? 32.663 38.245 9.823 1.00 11.02 ? 386 VAL A CG1 1 ATOM 2998 C CG2 . VAL A 1 386 ? 32.783 39.577 11.985 1.00 11.94 ? 386 VAL A CG2 1 ATOM 2999 N N . HIS A 1 387 ? 35.487 36.269 10.564 1.00 11.94 ? 387 HIS A N 1 ATOM 3000 C CA . HIS A 1 387 ? 35.993 35.247 9.694 1.00 13.21 ? 387 HIS A CA 1 ATOM 3001 C C . HIS A 1 387 ? 36.213 33.910 10.369 1.00 13.45 ? 387 HIS A C 1 ATOM 3002 O O . HIS A 1 387 ? 36.123 32.890 9.697 1.00 12.65 ? 387 HIS A O 1 ATOM 3003 C CB . HIS A 1 387 ? 37.232 35.716 8.949 1.00 11.27 ? 387 HIS A CB 1 ATOM 3004 C CG . HIS A 1 387 ? 36.946 36.825 7.984 1.00 11.78 ? 387 HIS A CG 1 ATOM 3005 N ND1 . HIS A 1 387 ? 36.032 36.712 6.956 1.00 13.78 ? 387 HIS A ND1 1 ATOM 3006 C CD2 . HIS A 1 387 ? 37.397 38.108 7.950 1.00 12.40 ? 387 HIS A CD2 1 ATOM 3007 C CE1 . HIS A 1 387 ? 35.916 37.882 6.344 1.00 11.40 ? 387 HIS A CE1 1 ATOM 3008 N NE2 . HIS A 1 387 ? 36.727 38.743 6.934 1.00 13.46 ? 387 HIS A NE2 1 ATOM 3009 N N . GLN A 1 388 ? 36.476 33.898 11.672 1.00 13.35 ? 388 GLN A N 1 ATOM 3010 C CA . GLN A 1 388 ? 36.586 32.604 12.386 1.00 15.10 ? 388 GLN A CA 1 ATOM 3011 C C . GLN A 1 388 ? 35.217 31.974 12.406 1.00 14.71 ? 388 GLN A C 1 ATOM 3012 O O . GLN A 1 388 ? 35.099 30.752 12.312 1.00 16.15 ? 388 GLN A O 1 ATOM 3013 C CB . GLN A 1 388 ? 37.077 32.817 13.816 1.00 16.05 ? 388 GLN A CB 1 ATOM 3014 C CG . GLN A 1 388 ? 38.600 32.948 13.938 1.00 22.41 ? 388 GLN A CG 1 ATOM 3015 C CD . GLN A 1 388 ? 39.051 33.857 15.088 1.00 26.09 ? 388 GLN A CD 1 ATOM 3016 O OE1 . GLN A 1 388 ? 38.252 34.225 15.948 1.00 28.15 ? 388 GLN A OE1 1 ATOM 3017 N NE2 . GLN A 1 388 ? 40.352 34.223 15.099 1.00 26.28 ? 388 GLN A NE2 1 ATOM 3018 N N . ALA A 1 389 ? 34.153 32.763 12.527 1.00 13.60 ? 389 ALA A N 1 ATOM 3019 C CA . ALA A 1 389 ? 32.792 32.217 12.515 1.00 14.40 ? 389 ALA A CA 1 ATOM 3020 C C . ALA A 1 389 ? 32.447 31.690 11.134 1.00 16.33 ? 389 ALA A C 1 ATOM 3021 O O . ALA A 1 389 ? 31.830 30.648 11.014 1.00 16.39 ? 389 ALA A O 1 ATOM 3022 C CB . ALA A 1 389 ? 31.775 33.263 12.957 1.00 14.95 ? 389 ALA A CB 1 ATOM 3023 N N . GLU A 1 390 ? 32.830 32.428 10.080 1.00 16.18 ? 390 GLU A N 1 ATOM 3024 C CA . GLU A 1 390 ? 32.618 32.001 8.692 1.00 17.61 ? 390 GLU A CA 1 ATOM 3025 C C . GLU A 1 390 ? 33.312 30.623 8.496 1.00 19.62 ? 390 GLU A C 1 ATOM 3026 O O . GLU A 1 390 ? 32.700 29.668 7.985 1.00 18.90 ? 390 GLU A O 1 ATOM 3027 C CB . GLU A 1 390 ? 33.279 33.046 7.755 1.00 15.23 ? 390 GLU A CB 1 ATOM 3028 C CG . GLU A 1 390 ? 33.099 32.797 6.268 1.00 16.47 ? 390 GLU A CG 1 ATOM 3029 C CD . GLU A 1 390 ? 33.824 33.825 5.426 1.00 21.24 ? 390 GLU A CD 1 ATOM 3030 O OE1 . GLU A 1 390 ? 34.715 34.526 5.953 1.00 20.59 ? 390 GLU A OE1 1 ATOM 3031 O OE2 . GLU A 1 390 ? 33.513 33.939 4.218 1.00 23.05 ? 390 GLU A OE2 1 ATOM 3032 N N . ARG A 1 391 ? 34.587 30.542 8.868 1.00 20.41 ? 391 ARG A N 1 ATOM 3033 C CA . ARG A 1 391 ? 35.331 29.304 8.732 1.00 22.09 ? 391 ARG A CA 1 ATOM 3034 C C . ARG A 1 391 ? 34.683 28.166 9.501 1.00 23.45 ? 391 ARG A C 1 ATOM 3035 O O . ARG A 1 391 ? 34.743 27.012 9.039 1.00 26.44 ? 391 ARG A O 1 ATOM 3036 C CB . ARG A 1 391 ? 36.764 29.465 9.173 1.00 22.36 ? 391 ARG A CB 1 ATOM 3037 C CG . ARG A 1 391 ? 37.594 30.250 8.168 1.00 25.13 ? 391 ARG A CG 1 ATOM 3038 C CD . ARG A 1 391 ? 39.072 30.140 8.446 1.00 28.31 ? 391 ARG A CD 1 ATOM 3039 N NE . ARG A 1 391 ? 39.426 30.551 9.805 1.00 31.18 ? 391 ARG A NE 1 ATOM 3040 C CZ . ARG A 1 391 ? 39.674 31.812 10.161 1.00 32.77 ? 391 ARG A CZ 1 ATOM 3041 N NH1 . ARG A 1 391 ? 39.612 32.798 9.255 1.00 31.98 ? 391 ARG A NH1 1 ATOM 3042 N NH2 . ARG A 1 391 ? 39.984 32.080 11.424 1.00 34.36 ? 391 ARG A NH2 1 ATOM 3043 N N . ALA A 1 392 ? 34.104 28.443 10.664 1.00 23.76 ? 392 ALA A N 1 ATOM 3044 C CA . ALA A 1 392 ? 33.426 27.383 11.426 1.00 24.44 ? 392 ALA A CA 1 ATOM 3045 C C . ALA A 1 392 ? 32.101 27.003 10.721 1.00 25.25 ? 392 ALA A C 1 ATOM 3046 O O . ALA A 1 392 ? 31.343 26.152 11.221 1.00 27.48 ? 392 ALA A O 1 ATOM 3047 C CB . ALA A 1 392 ? 33.145 27.838 12.843 1.00 23.87 ? 392 ALA A CB 1 ATOM 3048 N N . GLY A 1 393 ? 31.841 27.601 9.551 1.00 24.72 ? 393 GLY A N 1 ATOM 3049 C CA . GLY A 1 393 ? 30.617 27.286 8.820 1.00 22.62 ? 393 GLY A CA 1 ATOM 3050 C C . GLY A 1 393 ? 29.356 27.901 9.394 1.00 20.64 ? 393 GLY A C 1 ATOM 3051 O O . GLY A 1 393 ? 28.241 27.493 9.082 1.00 22.04 ? 393 GLY A O 1 ATOM 3052 N N . GLN A 1 394 ? 29.524 28.956 10.169 1.00 21.37 ? 394 GLN A N 1 ATOM 3053 C CA . GLN A 1 394 ? 28.374 29.576 10.804 1.00 22.02 ? 394 GLN A CA 1 ATOM 3054 C C . GLN A 1 394 ? 27.655 30.637 9.960 1.00 21.44 ? 394 GLN A C 1 ATOM 3055 O O . GLN A 1 394 ? 26.552 31.076 10.283 1.00 22.44 ? 394 GLN A O 1 ATOM 3056 C CB . GLN A 1 394 ? 28.840 30.133 12.157 1.00 24.06 ? 394 GLN A CB 1 ATOM 3057 C CG . GLN A 1 394 ? 27.800 30.871 12.960 1.00 25.20 ? 394 GLN A CG 1 ATOM 3058 C CD . GLN A 1 394 ? 28.451 31.781 13.996 1.00 26.50 ? 394 GLN A CD 1 ATOM 3059 O OE1 . GLN A 1 394 ? 28.228 32.992 13.980 1.00 23.57 ? 394 GLN A OE1 1 ATOM 3060 N NE2 . GLN A 1 394 ? 29.284 31.200 14.884 1.00 26.07 ? 394 GLN A NE2 1 ATOM 3061 N N . ALA A 1 395 ? 28.289 31.036 8.867 1.00 19.65 ? 395 ALA A N 1 ATOM 3062 C CA . ALA A 1 395 ? 27.723 32.023 7.967 1.00 18.59 ? 395 ALA A CA 1 ATOM 3063 C C . ALA A 1 395 ? 28.421 31.971 6.617 1.00 17.91 ? 395 ALA A C 1 ATOM 3064 O O . ALA A 1 395 ? 29.578 31.569 6.504 1.00 17.52 ? 395 ALA A O 1 ATOM 3065 C CB . ALA A 1 395 ? 27.878 33.435 8.568 1.00 19.33 ? 395 ALA A CB 1 ATOM 3066 N N . GLU A 1 396 ? 27.694 32.371 5.591 1.00 19.53 ? 396 GLU A N 1 ATOM 3067 C CA . GLU A 1 396 ? 28.259 32.480 4.247 1.00 19.85 ? 396 GLU A CA 1 ATOM 3068 C C . GLU A 1 396 ? 27.844 33.881 3.838 1.00 17.25 ? 396 GLU A C 1 ATOM 3069 O O . GLU A 1 396 ? 26.790 34.380 4.256 1.00 19.08 ? 396 GLU A O 1 ATOM 3070 C CB . GLU A 1 396 ? 27.663 31.439 3.302 1.00 23.77 ? 396 GLU A CB 1 ATOM 3071 C CG . GLU A 1 396 ? 26.161 31.523 3.310 1.00 30.05 ? 396 GLU A CG 1 ATOM 3072 C CD . GLU A 1 396 ? 25.493 30.204 2.954 1.00 32.92 ? 396 GLU A CD 1 ATOM 3073 O OE1 . GLU A 1 396 ? 26.165 29.375 2.301 1.00 34.65 ? 396 GLU A OE1 1 ATOM 3074 O OE2 . GLU A 1 396 ? 24.304 30.019 3.327 1.00 35.51 ? 396 GLU A OE2 1 ATOM 3075 N N . PHE A 1 397 ? 28.669 34.523 3.037 1.00 14.12 ? 397 PHE A N 1 ATOM 3076 C CA . PHE A 1 397 ? 28.348 35.884 2.692 1.00 12.15 ? 397 PHE A CA 1 ATOM 3077 C C . PHE A 1 397 ? 28.022 36.096 1.225 1.00 11.20 ? 397 PHE A C 1 ATOM 3078 O O . PHE A 1 397 ? 28.663 35.504 0.390 1.00 13.24 ? 397 PHE A O 1 ATOM 3079 C CB . PHE A 1 397 ? 29.561 36.776 3.043 1.00 12.96 ? 397 PHE A CB 1 ATOM 3080 C CG . PHE A 1 397 ? 29.884 36.800 4.499 1.00 11.12 ? 397 PHE A CG 1 ATOM 3081 C CD1 . PHE A 1 397 ? 29.060 37.522 5.383 1.00 11.54 ? 397 PHE A CD1 1 ATOM 3082 C CD2 . PHE A 1 397 ? 30.949 36.060 5.019 1.00 12.57 ? 397 PHE A CD2 1 ATOM 3083 C CE1 . PHE A 1 397 ? 29.250 37.518 6.794 1.00 9.85 ? 397 PHE A CE1 1 ATOM 3084 C CE2 . PHE A 1 397 ? 31.158 36.044 6.447 1.00 12.73 ? 397 PHE A CE2 1 ATOM 3085 C CZ . PHE A 1 397 ? 30.301 36.771 7.321 1.00 12.00 ? 397 PHE A CZ 1 ATOM 3086 N N . PRO A 1 398 ? 27.109 37.038 0.924 1.00 10.41 ? 398 PRO A N 1 ATOM 3087 C CA . PRO A 1 398 ? 26.734 37.350 -0.478 1.00 9.76 ? 398 PRO A CA 1 ATOM 3088 C C . PRO A 1 398 ? 27.829 38.128 -1.219 1.00 10.68 ? 398 PRO A C 1 ATOM 3089 O O . PRO A 1 398 ? 28.684 38.787 -0.593 1.00 10.10 ? 398 PRO A O 1 ATOM 3090 C CB . PRO A 1 398 ? 25.506 38.212 -0.324 1.00 9.42 ? 398 PRO A CB 1 ATOM 3091 C CG . PRO A 1 398 ? 25.761 38.942 1.002 1.00 10.15 ? 398 PRO A CG 1 ATOM 3092 C CD . PRO A 1 398 ? 26.400 37.906 1.886 1.00 11.72 ? 398 PRO A CD 1 ATOM 3093 N N . THR A 1 399 ? 27.824 37.990 -2.530 1.00 8.63 ? 399 THR A N 1 ATOM 3094 C CA . THR A 1 399 ? 28.748 38.716 -3.418 1.00 9.27 ? 399 THR A CA 1 ATOM 3095 C C . THR A 1 399 ? 27.973 39.949 -3.928 1.00 8.74 ? 399 THR A C 1 ATOM 3096 O O . THR A 1 399 ? 26.723 39.947 -4.061 1.00 9.16 ? 399 THR A O 1 ATOM 3097 C CB . THR A 1 399 ? 29.177 37.866 -4.623 1.00 10.10 ? 399 THR A CB 1 ATOM 3098 O OG1 . THR A 1 399 ? 28.029 37.505 -5.389 1.00 11.07 ? 399 THR A OG1 1 ATOM 3099 C CG2 . THR A 1 399 ? 29.936 36.633 -4.158 1.00 11.40 ? 399 THR A CG2 1 ATOM 3100 N N . LEU A 1 400 ? 28.739 41.007 -4.225 1.00 7.75 ? 400 LEU A N 1 ATOM 3101 C CA . LEU A 1 400 ? 28.116 42.276 -4.624 1.00 8.25 ? 400 LEU A CA 1 ATOM 3102 C C . LEU A 1 400 ? 29.023 43.052 -5.543 1.00 8.22 ? 400 LEU A C 1 ATOM 3103 O O . LEU A 1 400 ? 30.264 42.992 -5.392 1.00 10.36 ? 400 LEU A O 1 ATOM 3104 C CB . LEU A 1 400 ? 27.862 43.207 -3.385 1.00 7.37 ? 400 LEU A CB 1 ATOM 3105 C CG . LEU A 1 400 ? 27.198 44.589 -3.610 1.00 7.20 ? 400 LEU A CG 1 ATOM 3106 C CD1 . LEU A 1 400 ? 26.356 44.962 -2.384 1.00 7.83 ? 400 LEU A CD1 1 ATOM 3107 C CD2 . LEU A 1 400 ? 28.288 45.665 -3.840 1.00 7.89 ? 400 LEU A CD2 1 ATOM 3108 N N . SER A 1 401 ? 28.431 43.690 -6.552 1.00 7.75 ? 401 SER A N 1 ATOM 3109 C CA . SER A 1 401 ? 29.240 44.624 -7.396 1.00 7.69 ? 401 SER A CA 1 ATOM 3110 C C . SER A 1 401 ? 28.360 45.859 -7.582 1.00 9.39 ? 401 SER A C 1 ATOM 3111 O O . SER A 1 401 ? 27.133 45.828 -7.381 1.00 6.85 ? 401 SER A O 1 ATOM 3112 C CB . SER A 1 401 ? 29.600 44.096 -8.788 1.00 9.48 ? 401 SER A CB 1 ATOM 3113 O OG . SER A 1 401 ? 28.444 44.042 -9.656 1.00 7.78 ? 401 SER A OG 1 ATOM 3114 N N . GLY A 1 402 ? 29.034 46.948 -7.940 1.00 7.51 ? 402 GLY A N 1 ATOM 3115 C CA . GLY A 1 402 ? 28.399 48.265 -8.142 1.00 6.98 ? 402 GLY A CA 1 ATOM 3116 C C . GLY A 1 402 ? 28.984 49.330 -7.230 1.00 7.54 ? 402 GLY A C 1 ATOM 3117 O O . GLY A 1 402 ? 30.054 49.133 -6.632 1.00 7.66 ? 402 GLY A O 1 ATOM 3118 N N . ASP A 1 403 ? 28.307 50.475 -7.142 1.00 7.34 ? 403 ASP A N 1 ATOM 3119 C CA . ASP A 1 403 ? 28.761 51.629 -6.310 1.00 7.63 ? 403 ASP A CA 1 ATOM 3120 C C . ASP A 1 403 ? 27.656 52.104 -5.385 1.00 6.51 ? 403 ASP A C 1 ATOM 3121 O O . ASP A 1 403 ? 26.549 51.524 -5.397 1.00 7.79 ? 403 ASP A O 1 ATOM 3122 C CB . ASP A 1 403 ? 29.308 52.764 -7.219 1.00 5.90 ? 403 ASP A CB 1 ATOM 3123 C CG . ASP A 1 403 ? 28.245 53.544 -7.923 1.00 9.84 ? 403 ASP A CG 1 ATOM 3124 O OD1 . ASP A 1 403 ? 27.110 53.075 -8.060 1.00 10.80 ? 403 ASP A OD1 1 ATOM 3125 O OD2 . ASP A 1 403 ? 28.595 54.656 -8.364 1.00 10.43 ? 403 ASP A OD2 1 ATOM 3126 N N . PHE A 1 404 ? 27.951 53.099 -4.565 1.00 6.47 ? 404 PHE A N 1 ATOM 3127 C CA . PHE A 1 404 ? 26.998 53.602 -3.643 1.00 5.20 ? 404 PHE A CA 1 ATOM 3128 C C . PHE A 1 404 ? 26.876 55.101 -3.790 1.00 6.29 ? 404 PHE A C 1 ATOM 3129 O O . PHE A 1 404 ? 26.990 55.829 -2.825 1.00 6.02 ? 404 PHE A O 1 ATOM 3130 C CB . PHE A 1 404 ? 27.382 53.157 -2.220 1.00 5.51 ? 404 PHE A CB 1 ATOM 3131 C CG . PHE A 1 404 ? 27.333 51.693 -2.059 1.00 5.42 ? 404 PHE A CG 1 ATOM 3132 C CD1 . PHE A 1 404 ? 26.062 51.056 -1.949 1.00 7.02 ? 404 PHE A CD1 1 ATOM 3133 C CD2 . PHE A 1 404 ? 28.497 50.958 -2.042 1.00 6.79 ? 404 PHE A CD2 1 ATOM 3134 C CE1 . PHE A 1 404 ? 25.975 49.660 -1.796 1.00 6.84 ? 404 PHE A CE1 1 ATOM 3135 C CE2 . PHE A 1 404 ? 28.456 49.583 -1.918 1.00 6.55 ? 404 PHE A CE2 1 ATOM 3136 C CZ . PHE A 1 404 ? 27.172 48.948 -1.789 1.00 6.40 ? 404 PHE A CZ 1 ATOM 3137 N N . PHE A 1 405 ? 26.624 55.503 -5.039 1.00 6.90 ? 405 PHE A N 1 ATOM 3138 C CA . PHE A 1 405 ? 26.297 56.927 -5.384 1.00 7.03 ? 405 PHE A CA 1 ATOM 3139 C C . PHE A 1 405 ? 24.931 56.861 -6.111 1.00 7.50 ? 405 PHE A C 1 ATOM 3140 O O . PHE A 1 405 ? 24.639 55.888 -6.832 1.00 8.26 ? 405 PHE A O 1 ATOM 3141 C CB . PHE A 1 405 ? 27.341 57.516 -6.364 1.00 6.46 ? 405 PHE A CB 1 ATOM 3142 C CG . PHE A 1 405 ? 28.733 57.644 -5.763 1.00 6.39 ? 405 PHE A CG 1 ATOM 3143 C CD1 . PHE A 1 405 ? 28.972 58.443 -4.671 1.00 6.54 ? 405 PHE A CD1 1 ATOM 3144 C CD2 . PHE A 1 405 ? 29.747 56.949 -6.333 1.00 7.18 ? 405 PHE A CD2 1 ATOM 3145 C CE1 . PHE A 1 405 ? 30.302 58.545 -4.145 1.00 4.50 ? 405 PHE A CE1 1 ATOM 3146 C CE2 . PHE A 1 405 ? 31.054 57.031 -5.838 1.00 9.02 ? 405 PHE A CE2 1 ATOM 3147 C CZ . PHE A 1 405 ? 31.319 57.831 -4.741 1.00 5.85 ? 405 PHE A CZ 1 ATOM 3148 N N . THR A 1 406 ? 24.080 57.879 -5.964 1.00 7.80 ? 406 THR A N 1 ATOM 3149 C CA . THR A 1 406 ? 24.318 59.075 -5.168 1.00 9.27 ? 406 THR A CA 1 ATOM 3150 C C . THR A 1 406 ? 23.683 58.985 -3.806 1.00 8.92 ? 406 THR A C 1 ATOM 3151 O O . THR A 1 406 ? 22.496 58.586 -3.672 1.00 9.84 ? 406 THR A O 1 ATOM 3152 C CB . THR A 1 406 ? 23.779 60.297 -5.948 1.00 9.17 ? 406 THR A CB 1 ATOM 3153 O OG1 . THR A 1 406 ? 24.716 60.509 -7.030 1.00 8.58 ? 406 THR A OG1 1 ATOM 3154 C CG2 . THR A 1 406 ? 23.709 61.587 -5.133 1.00 8.71 ? 406 THR A CG2 1 ATOM 3155 N N . TYR A 1 407 ? 24.448 59.317 -2.788 1.00 8.03 ? 407 TYR A N 1 ATOM 3156 C CA . TYR A 1 407 ? 24.036 59.234 -1.418 1.00 7.13 ? 407 TYR A CA 1 ATOM 3157 C C . TYR A 1 407 ? 22.894 60.193 -0.985 1.00 7.50 ? 407 TYR A C 1 ATOM 3158 O O . TYR A 1 407 ? 22.890 61.323 -1.447 1.00 8.73 ? 407 TYR A O 1 ATOM 3159 C CB . TYR A 1 407 ? 25.290 59.485 -0.547 1.00 7.82 ? 407 TYR A CB 1 ATOM 3160 C CG . TYR A 1 407 ? 25.015 59.623 0.900 1.00 6.21 ? 407 TYR A CG 1 ATOM 3161 C CD1 . TYR A 1 407 ? 24.545 58.542 1.654 1.00 7.92 ? 407 TYR A CD1 1 ATOM 3162 C CD2 . TYR A 1 407 ? 25.320 60.822 1.570 1.00 8.71 ? 407 TYR A CD2 1 ATOM 3163 C CE1 . TYR A 1 407 ? 24.415 58.627 3.044 1.00 6.83 ? 407 TYR A CE1 1 ATOM 3164 C CE2 . TYR A 1 407 ? 25.193 60.954 2.974 1.00 5.52 ? 407 TYR A CE2 1 ATOM 3165 C CZ . TYR A 1 407 ? 24.737 59.835 3.737 1.00 8.52 ? 407 TYR A CZ 1 ATOM 3166 O OH . TYR A 1 407 ? 24.736 59.962 5.093 1.00 7.24 ? 407 TYR A OH 1 ATOM 3167 N N . ALA A 1 408 ? 21.929 59.752 -0.146 1.00 8.87 ? 408 ALA A N 1 ATOM 3168 C CA . ALA A 1 408 ? 20.968 60.668 0.415 1.00 8.33 ? 408 ALA A CA 1 ATOM 3169 C C . ALA A 1 408 ? 20.911 60.125 1.858 1.00 7.80 ? 408 ALA A C 1 ATOM 3170 O O . ALA A 1 408 ? 20.794 58.873 2.049 1.00 8.89 ? 408 ALA A O 1 ATOM 3171 C CB . ALA A 1 408 ? 19.571 60.576 -0.233 1.00 9.40 ? 408 ALA A CB 1 ATOM 3172 N N . ASP A 1 409 ? 20.964 61.026 2.847 1.00 10.01 ? 409 ASP A N 1 ATOM 3173 C CA . ASP A 1 409 ? 20.924 60.680 4.289 1.00 9.88 ? 409 ASP A CA 1 ATOM 3174 C C . ASP A 1 409 ? 19.513 60.742 4.827 1.00 11.88 ? 409 ASP A C 1 ATOM 3175 O O . ASP A 1 409 ? 19.214 60.080 5.833 1.00 10.92 ? 409 ASP A O 1 ATOM 3176 C CB . ASP A 1 409 ? 21.875 61.563 5.119 1.00 9.51 ? 409 ASP A CB 1 ATOM 3177 C CG . ASP A 1 409 ? 21.568 63.096 5.040 1.00 8.29 ? 409 ASP A CG 1 ATOM 3178 O OD1 . ASP A 1 409 ? 20.956 63.548 4.050 1.00 10.02 ? 409 ASP A OD1 1 ATOM 3179 O OD2 . ASP A 1 409 ? 22.031 63.799 5.998 1.00 11.87 ? 409 ASP A OD2 1 ATOM 3180 N N . ARG A 1 410 ? 18.646 61.473 4.108 1.00 9.74 ? 410 ARG A N 1 ATOM 3181 C CA . ARG A 1 410 ? 17.199 61.528 4.503 1.00 12.89 ? 410 ARG A CA 1 ATOM 3182 C C . ARG A 1 410 ? 16.381 62.162 3.386 1.00 12.16 ? 410 ARG A C 1 ATOM 3183 O O . ARG A 1 410 ? 16.923 62.919 2.536 1.00 13.40 ? 410 ARG A O 1 ATOM 3184 C CB . ARG A 1 410 ? 16.975 62.298 5.803 1.00 13.23 ? 410 ARG A CB 1 ATOM 3185 C CG . ARG A 1 410 ? 17.517 63.722 5.792 1.00 15.52 ? 410 ARG A CG 1 ATOM 3186 C CD . ARG A 1 410 ? 17.500 64.269 7.223 1.00 16.78 ? 410 ARG A CD 1 ATOM 3187 N NE . ARG A 1 410 ? 18.023 65.641 7.353 1.00 18.72 ? 410 ARG A NE 1 ATOM 3188 C CZ . ARG A 1 410 ? 17.357 66.748 7.031 1.00 20.49 ? 410 ARG A CZ 1 ATOM 3189 N NH1 . ARG A 1 410 ? 16.115 66.676 6.533 1.00 21.45 ? 410 ARG A NH1 1 ATOM 3190 N NH2 . ARG A 1 410 ? 17.939 67.937 7.234 1.00 20.18 ? 410 ARG A NH2 1 ATOM 3191 N N . SER A 1 411 ? 15.081 61.860 3.389 1.00 13.35 ? 411 SER A N 1 ATOM 3192 C CA . SER A 1 411 ? 14.112 62.378 2.402 1.00 14.43 ? 411 SER A CA 1 ATOM 3193 C C . SER A 1 411 ? 14.663 62.527 0.981 1.00 13.45 ? 411 SER A C 1 ATOM 3194 O O . SER A 1 411 ? 15.138 61.540 0.434 1.00 13.60 ? 411 SER A O 1 ATOM 3195 C CB . SER A 1 411 ? 13.486 63.708 2.898 1.00 16.39 ? 411 SER A CB 1 ATOM 3196 O OG A SER A 1 411 ? 14.330 64.818 2.687 0.50 17.21 ? 411 SER A OG 1 ATOM 3197 O OG B SER A 1 411 ? 14.252 64.310 3.951 0.50 14.37 ? 411 SER A OG 1 ATOM 3198 N N . ASP A 1 412 ? 14.597 63.734 0.391 1.00 11.91 ? 412 ASP A N 1 ATOM 3199 C CA . ASP A 1 412 ? 15.092 63.957 -0.972 1.00 13.04 ? 412 ASP A CA 1 ATOM 3200 C C . ASP A 1 412 ? 16.437 64.700 -0.955 1.00 10.20 ? 412 ASP A C 1 ATOM 3201 O O . ASP A 1 412 ? 16.835 65.268 -1.984 1.00 11.42 ? 412 ASP A O 1 ATOM 3202 C CB . ASP A 1 412 ? 14.091 64.789 -1.803 1.00 14.75 ? 412 ASP A CB 1 ATOM 3203 C CG . ASP A 1 412 ? 13.884 66.203 -1.257 1.00 15.15 ? 412 ASP A CG 1 ATOM 3204 O OD1 . ASP A 1 412 ? 14.340 66.546 -0.170 1.00 13.69 ? 412 ASP A OD1 1 ATOM 3205 O OD2 . ASP A 1 412 ? 13.216 66.994 -1.974 1.00 17.42 ? 412 ASP A OD2 1 ATOM 3206 N N . ASN A 1 413 ? 17.114 64.669 0.191 1.00 10.16 ? 413 ASN A N 1 ATOM 3207 C CA . ASN A 1 413 ? 18.403 65.381 0.337 1.00 10.22 ? 413 ASN A CA 1 ATOM 3208 C C . ASN A 1 413 ? 19.544 64.496 -0.247 1.00 9.60 ? 413 ASN A C 1 ATOM 3209 O O . ASN A 1 413 ? 20.176 63.745 0.480 1.00 10.30 ? 413 ASN A O 1 ATOM 3210 C CB . ASN A 1 413 ? 18.682 65.732 1.821 1.00 9.29 ? 413 ASN A CB 1 ATOM 3211 C CG . ASN A 1 413 ? 17.694 66.770 2.441 1.00 10.68 ? 413 ASN A CG 1 ATOM 3212 O OD1 . ASN A 1 413 ? 17.971 67.264 3.511 1.00 10.63 ? 413 ASN A OD1 1 ATOM 3213 N ND2 . ASN A 1 413 ? 16.589 67.087 1.762 1.00 10.76 ? 413 ASN A ND2 1 ATOM 3214 N N . TYR A 1 414 ? 19.742 64.581 -1.559 1.00 10.36 ? 414 TYR A N 1 ATOM 3215 C CA . TYR A 1 414 ? 20.791 63.848 -2.328 1.00 9.12 ? 414 TYR A CA 1 ATOM 3216 C C . TYR A 1 414 ? 22.039 64.748 -2.367 1.00 9.29 ? 414 TYR A C 1 ATOM 3217 O O . TYR A 1 414 ? 21.960 65.955 -2.643 1.00 10.15 ? 414 TYR A O 1 ATOM 3218 C CB . TYR A 1 414 ? 20.344 63.532 -3.762 1.00 8.99 ? 414 TYR A CB 1 ATOM 3219 C CG . TYR A 1 414 ? 19.348 62.384 -3.783 1.00 11.30 ? 414 TYR A CG 1 ATOM 3220 C CD1 . TYR A 1 414 ? 17.983 62.619 -3.568 1.00 13.28 ? 414 TYR A CD1 1 ATOM 3221 C CD2 . TYR A 1 414 ? 19.778 61.087 -3.941 1.00 11.06 ? 414 TYR A CD2 1 ATOM 3222 C CE1 . TYR A 1 414 ? 17.103 61.579 -3.526 1.00 11.73 ? 414 TYR A CE1 1 ATOM 3223 C CE2 . TYR A 1 414 ? 18.895 60.045 -3.872 1.00 10.52 ? 414 TYR A CE2 1 ATOM 3224 C CZ . TYR A 1 414 ? 17.562 60.301 -3.671 1.00 11.05 ? 414 TYR A CZ 1 ATOM 3225 O OH . TYR A 1 414 ? 16.714 59.224 -3.637 1.00 11.43 ? 414 TYR A OH 1 ATOM 3226 N N . TRP A 1 415 ? 23.176 64.129 -2.035 1.00 6.71 ? 415 TRP A N 1 ATOM 3227 C CA . TRP A 1 415 ? 24.452 64.840 -1.918 1.00 8.43 ? 415 TRP A CA 1 ATOM 3228 C C . TRP A 1 415 ? 25.222 64.915 -3.238 1.00 9.82 ? 415 TRP A C 1 ATOM 3229 O O . TRP A 1 415 ? 26.351 64.452 -3.356 1.00 9.33 ? 415 TRP A O 1 ATOM 3230 C CB . TRP A 1 415 ? 25.261 64.123 -0.835 1.00 7.35 ? 415 TRP A CB 1 ATOM 3231 C CG . TRP A 1 415 ? 24.659 64.217 0.561 1.00 6.93 ? 415 TRP A CG 1 ATOM 3232 C CD1 . TRP A 1 415 ? 23.339 63.979 0.935 1.00 7.30 ? 415 TRP A CD1 1 ATOM 3233 C CD2 . TRP A 1 415 ? 25.376 64.439 1.782 1.00 7.01 ? 415 TRP A CD2 1 ATOM 3234 N NE1 . TRP A 1 415 ? 23.241 64.043 2.309 1.00 6.94 ? 415 TRP A NE1 1 ATOM 3235 C CE2 . TRP A 1 415 ? 24.459 64.327 2.856 1.00 10.06 ? 415 TRP A CE2 1 ATOM 3236 C CE3 . TRP A 1 415 ? 26.744 64.715 2.067 1.00 8.82 ? 415 TRP A CE3 1 ATOM 3237 C CZ2 . TRP A 1 415 ? 24.831 64.480 4.199 1.00 8.63 ? 415 TRP A CZ2 1 ATOM 3238 C CZ3 . TRP A 1 415 ? 27.131 64.856 3.374 1.00 6.96 ? 415 TRP A CZ3 1 ATOM 3239 C CH2 . TRP A 1 415 ? 26.175 64.744 4.475 1.00 8.73 ? 415 TRP A CH2 1 ATOM 3240 N N . SER A 1 416 ? 24.591 65.459 -4.247 1.00 7.52 ? 416 SER A N 1 ATOM 3241 C CA . SER A 1 416 ? 25.242 65.626 -5.538 1.00 6.47 ? 416 SER A CA 1 ATOM 3242 C C . SER A 1 416 ? 25.838 67.034 -5.706 1.00 7.15 ? 416 SER A C 1 ATOM 3243 O O . SER A 1 416 ? 26.510 67.261 -6.707 1.00 7.28 ? 416 SER A O 1 ATOM 3244 C CB . SER A 1 416 ? 24.264 65.310 -6.699 1.00 7.00 ? 416 SER A CB 1 ATOM 3245 O OG . SER A 1 416 ? 22.907 65.785 -6.500 1.00 8.08 ? 416 SER A OG 1 ATOM 3246 N N . GLY A 1 417 ? 25.604 67.928 -4.746 1.00 7.27 ? 417 GLY A N 1 ATOM 3247 C CA . GLY A 1 417 ? 26.167 69.252 -4.922 1.00 7.72 ? 417 GLY A CA 1 ATOM 3248 C C . GLY A 1 417 ? 27.690 69.249 -4.852 1.00 8.48 ? 417 GLY A C 1 ATOM 3249 O O . GLY A 1 417 ? 28.345 69.987 -5.585 1.00 7.87 ? 417 GLY A O 1 ATOM 3250 N N . TYR A 1 418 ? 28.255 68.428 -3.979 1.00 7.84 ? 418 TYR A N 1 ATOM 3251 C CA . TYR A 1 418 ? 29.709 68.457 -3.807 1.00 6.73 ? 418 TYR A CA 1 ATOM 3252 C C . TYR A 1 418 ? 30.426 67.818 -4.975 1.00 6.58 ? 418 TYR A C 1 ATOM 3253 O O . TYR A 1 418 ? 31.666 67.848 -5.051 1.00 8.01 ? 418 TYR A O 1 ATOM 3254 C CB . TYR A 1 418 ? 30.085 67.802 -2.481 1.00 8.17 ? 418 TYR A CB 1 ATOM 3255 C CG . TYR A 1 418 ? 30.199 66.296 -2.504 1.00 7.58 ? 418 TYR A CG 1 ATOM 3256 C CD1 . TYR A 1 418 ? 29.077 65.477 -2.299 1.00 8.03 ? 418 TYR A CD1 1 ATOM 3257 C CD2 . TYR A 1 418 ? 31.443 65.706 -2.720 1.00 6.59 ? 418 TYR A CD2 1 ATOM 3258 C CE1 . TYR A 1 418 ? 29.200 64.066 -2.316 1.00 7.52 ? 418 TYR A CE1 1 ATOM 3259 C CE2 . TYR A 1 418 ? 31.581 64.328 -2.747 1.00 6.76 ? 418 TYR A CE2 1 ATOM 3260 C CZ . TYR A 1 418 ? 30.467 63.522 -2.541 1.00 5.68 ? 418 TYR A CZ 1 ATOM 3261 O OH . TYR A 1 418 ? 30.631 62.144 -2.574 1.00 6.23 ? 418 TYR A OH 1 ATOM 3262 N N . TYR A 1 419 ? 29.711 67.288 -5.957 1.00 4.96 ? 419 TYR A N 1 ATOM 3263 C CA . TYR A 1 419 ? 30.409 66.825 -7.151 1.00 6.44 ? 419 TYR A CA 1 ATOM 3264 C C . TYR A 1 419 ? 30.920 68.085 -7.912 1.00 6.96 ? 419 TYR A C 1 ATOM 3265 O O . TYR A 1 419 ? 31.733 67.940 -8.811 1.00 7.07 ? 419 TYR A O 1 ATOM 3266 C CB . TYR A 1 419 ? 29.461 66.054 -8.110 1.00 6.58 ? 419 TYR A CB 1 ATOM 3267 C CG . TYR A 1 419 ? 28.758 64.876 -7.463 1.00 8.38 ? 419 TYR A CG 1 ATOM 3268 C CD1 . TYR A 1 419 ? 29.333 64.210 -6.351 1.00 6.80 ? 419 TYR A CD1 1 ATOM 3269 C CD2 . TYR A 1 419 ? 27.603 64.370 -7.989 1.00 6.77 ? 419 TYR A CD2 1 ATOM 3270 C CE1 . TYR A 1 419 ? 28.770 63.028 -5.763 1.00 7.87 ? 419 TYR A CE1 1 ATOM 3271 C CE2 . TYR A 1 419 ? 27.029 63.198 -7.446 1.00 8.37 ? 419 TYR A CE2 1 ATOM 3272 C CZ . TYR A 1 419 ? 27.627 62.552 -6.340 1.00 8.22 ? 419 TYR A CZ 1 ATOM 3273 O OH . TYR A 1 419 ? 27.040 61.411 -5.824 1.00 8.06 ? 419 TYR A OH 1 ATOM 3274 N N . THR A 1 420 ? 30.392 69.277 -7.586 1.00 6.87 ? 420 THR A N 1 ATOM 3275 C CA . THR A 1 420 ? 30.812 70.496 -8.278 1.00 8.60 ? 420 THR A CA 1 ATOM 3276 C C . THR A 1 420 ? 31.352 71.594 -7.406 1.00 8.92 ? 420 THR A C 1 ATOM 3277 O O . THR A 1 420 ? 32.143 72.413 -7.863 1.00 8.47 ? 420 THR A O 1 ATOM 3278 C CB . THR A 1 420 ? 29.580 71.020 -9.103 1.00 7.46 ? 420 THR A CB 1 ATOM 3279 O OG1 . THR A 1 420 ? 29.082 69.990 -9.958 1.00 8.83 ? 420 THR A OG1 1 ATOM 3280 C CG2 . THR A 1 420 ? 29.946 72.350 -9.850 1.00 9.10 ? 420 THR A CG2 1 ATOM 3281 N N . SER A 1 421 ? 30.967 71.635 -6.139 1.00 7.68 ? 421 SER A N 1 ATOM 3282 C CA . SER A 1 421 ? 31.393 72.740 -5.254 1.00 9.42 ? 421 SER A CA 1 ATOM 3283 C C . SER A 1 421 ? 32.876 73.076 -5.314 1.00 10.18 ? 421 SER A C 1 ATOM 3284 O O . SER A 1 421 ? 33.738 72.150 -5.319 1.00 9.08 ? 421 SER A O 1 ATOM 3285 C CB . SER A 1 421 ? 31.005 72.448 -3.814 1.00 8.33 ? 421 SER A CB 1 ATOM 3286 O OG . SER A 1 421 ? 29.588 72.228 -3.705 1.00 8.68 ? 421 SER A OG 1 ATOM 3287 N N . ARG A 1 422 ? 33.173 74.390 -5.288 1.00 8.43 ? 422 ARG A N 1 ATOM 3288 C CA . ARG A 1 422 ? 34.580 74.913 -5.363 1.00 8.30 ? 422 ARG A CA 1 ATOM 3289 C C . ARG A 1 422 ? 35.302 74.267 -6.560 1.00 7.96 ? 422 ARG A C 1 ATOM 3290 O O . ARG A 1 422 ? 36.350 73.602 -6.368 1.00 7.13 ? 422 ARG A O 1 ATOM 3291 C CB . ARG A 1 422 ? 35.345 74.665 -4.032 1.00 11.13 ? 422 ARG A CB 1 ATOM 3292 C CG . ARG A 1 422 ? 35.065 75.647 -2.906 1.00 9.70 ? 422 ARG A CG 1 ATOM 3293 C CD . ARG A 1 422 ? 33.578 75.722 -2.546 1.00 10.10 ? 422 ARG A CD 1 ATOM 3294 N NE . ARG A 1 422 ? 33.515 76.730 -1.513 1.00 8.09 ? 422 ARG A NE 1 ATOM 3295 C CZ . ARG A 1 422 ? 33.539 76.487 -0.179 1.00 9.66 ? 422 ARG A CZ 1 ATOM 3296 N NH1 . ARG A 1 422 ? 33.545 75.245 0.266 1.00 10.07 ? 422 ARG A NH1 1 ATOM 3297 N NH2 . ARG A 1 422 ? 33.813 77.418 0.725 1.00 11.48 ? 422 ARG A NH2 1 ATOM 3298 N N . PRO A 1 423 ? 34.795 74.436 -7.783 1.00 8.09 ? 423 PRO A N 1 ATOM 3299 C CA . PRO A 1 423 ? 35.390 73.836 -8.972 1.00 7.75 ? 423 PRO A CA 1 ATOM 3300 C C . PRO A 1 423 ? 36.822 74.282 -9.325 1.00 9.23 ? 423 PRO A C 1 ATOM 3301 O O . PRO A 1 423 ? 37.526 73.554 -10.018 1.00 7.22 ? 423 PRO A O 1 ATOM 3302 C CB . PRO A 1 423 ? 34.344 74.137 -10.074 1.00 7.45 ? 423 PRO A CB 1 ATOM 3303 C CG . PRO A 1 423 ? 33.806 75.533 -9.677 1.00 7.42 ? 423 PRO A CG 1 ATOM 3304 C CD . PRO A 1 423 ? 33.676 75.369 -8.135 1.00 6.77 ? 423 PRO A CD 1 ATOM 3305 N N . TYR A 1 424 ? 37.210 75.468 -8.898 1.00 9.65 ? 424 TYR A N 1 ATOM 3306 C CA . TYR A 1 424 ? 38.571 75.921 -9.166 1.00 8.31 ? 424 TYR A CA 1 ATOM 3307 C C . TYR A 1 424 ? 39.568 74.949 -8.548 1.00 10.42 ? 424 TYR A C 1 ATOM 3308 O O . TYR A 1 424 ? 40.543 74.558 -9.177 1.00 9.16 ? 424 TYR A O 1 ATOM 3309 C CB . TYR A 1 424 ? 38.777 77.266 -8.493 1.00 9.32 ? 424 TYR A CB 1 ATOM 3310 C CG . TYR A 1 424 ? 40.161 77.831 -8.758 1.00 10.19 ? 424 TYR A CG 1 ATOM 3311 C CD1 . TYR A 1 424 ? 40.413 78.636 -9.891 1.00 12.60 ? 424 TYR A CD1 1 ATOM 3312 C CD2 . TYR A 1 424 ? 41.227 77.537 -7.902 1.00 10.70 ? 424 TYR A CD2 1 ATOM 3313 C CE1 . TYR A 1 424 ? 41.707 79.134 -10.148 1.00 13.52 ? 424 TYR A CE1 1 ATOM 3314 C CE2 . TYR A 1 424 ? 42.557 78.056 -8.144 1.00 13.87 ? 424 TYR A CE2 1 ATOM 3315 C CZ . TYR A 1 424 ? 42.750 78.853 -9.283 1.00 13.40 ? 424 TYR A CZ 1 ATOM 3316 O OH . TYR A 1 424 ? 43.992 79.444 -9.566 1.00 15.14 ? 424 TYR A OH 1 ATOM 3317 N N . HIS A 1 425 ? 39.298 74.577 -7.308 1.00 7.86 ? 425 HIS A N 1 ATOM 3318 C CA . HIS A 1 425 ? 40.214 73.635 -6.639 1.00 8.63 ? 425 HIS A CA 1 ATOM 3319 C C . HIS A 1 425 ? 40.102 72.191 -7.158 1.00 8.44 ? 425 HIS A C 1 ATOM 3320 O O . HIS A 1 425 ? 41.075 71.412 -7.117 1.00 8.01 ? 425 HIS A O 1 ATOM 3321 C CB . HIS A 1 425 ? 39.951 73.704 -5.157 1.00 8.79 ? 425 HIS A CB 1 ATOM 3322 C CG . HIS A 1 425 ? 40.052 75.100 -4.642 1.00 9.14 ? 425 HIS A CG 1 ATOM 3323 N ND1 . HIS A 1 425 ? 38.977 75.972 -4.692 1.00 12.41 ? 425 HIS A ND1 1 ATOM 3324 C CD2 . HIS A 1 425 ? 41.140 75.860 -4.364 1.00 11.23 ? 425 HIS A CD2 1 ATOM 3325 C CE1 . HIS A 1 425 ? 39.399 77.203 -4.490 1.00 12.95 ? 425 HIS A CE1 1 ATOM 3326 N NE2 . HIS A 1 425 ? 40.712 77.160 -4.294 1.00 11.59 ? 425 HIS A NE2 1 ATOM 3327 N N . LYS A 1 426 ? 38.897 71.790 -7.603 1.00 6.71 ? 426 LYS A N 1 ATOM 3328 C CA . LYS A 1 426 ? 38.744 70.493 -8.207 1.00 7.79 ? 426 LYS A CA 1 ATOM 3329 C C . LYS A 1 426 ? 39.644 70.452 -9.492 1.00 8.25 ? 426 LYS A C 1 ATOM 3330 O O . LYS A 1 426 ? 40.234 69.406 -9.814 1.00 8.52 ? 426 LYS A O 1 ATOM 3331 C CB . LYS A 1 426 ? 37.255 70.329 -8.579 1.00 6.36 ? 426 LYS A CB 1 ATOM 3332 C CG . LYS A 1 426 ? 36.426 69.882 -7.445 1.00 8.64 ? 426 LYS A CG 1 ATOM 3333 C CD . LYS A 1 426 ? 34.974 69.979 -7.882 1.00 6.14 ? 426 LYS A CD 1 ATOM 3334 C CE . LYS A 1 426 ? 34.037 69.080 -6.991 1.00 9.53 ? 426 LYS A CE 1 ATOM 3335 N NZ . LYS A 1 426 ? 33.967 69.489 -5.520 1.00 8.24 ? 426 LYS A NZ 1 ATOM 3336 N N . ARG A 1 427 ? 39.701 71.559 -10.259 1.00 7.90 ? 427 ARG A N 1 ATOM 3337 C CA . ARG A 1 427 ? 40.571 71.510 -11.438 1.00 8.08 ? 427 ARG A CA 1 ATOM 3338 C C . ARG A 1 427 ? 42.083 71.519 -10.992 1.00 8.97 ? 427 ARG A C 1 ATOM 3339 O O . ARG A 1 427 ? 42.948 70.834 -11.561 1.00 8.33 ? 427 ARG A O 1 ATOM 3340 C CB . ARG A 1 427 ? 40.220 72.758 -12.298 1.00 8.81 ? 427 ARG A CB 1 ATOM 3341 C CG . ARG A 1 427 ? 41.216 73.070 -13.388 1.00 10.19 ? 427 ARG A CG 1 ATOM 3342 C CD . ARG A 1 427 ? 41.326 72.025 -14.454 1.00 13.42 ? 427 ARG A CD 1 ATOM 3343 N NE . ARG A 1 427 ? 42.356 72.382 -15.452 1.00 12.13 ? 427 ARG A NE 1 ATOM 3344 C CZ . ARG A 1 427 ? 43.147 71.515 -16.056 1.00 12.20 ? 427 ARG A CZ 1 ATOM 3345 N NH1 . ARG A 1 427 ? 43.069 70.204 -15.843 1.00 11.41 ? 427 ARG A NH1 1 ATOM 3346 N NH2 . ARG A 1 427 ? 44.142 71.956 -16.841 1.00 14.05 ? 427 ARG A NH2 1 ATOM 3347 N N . MET A 1 428 ? 42.341 72.308 -9.960 1.00 8.72 ? 428 MET A N 1 ATOM 3348 C CA . MET A 1 428 ? 43.715 72.376 -9.464 1.00 8.85 ? 428 MET A CA 1 ATOM 3349 C C . MET A 1 428 ? 44.220 71.006 -9.046 1.00 8.84 ? 428 MET A C 1 ATOM 3350 O O . MET A 1 428 ? 45.379 70.706 -9.225 1.00 6.60 ? 428 MET A O 1 ATOM 3351 C CB . MET A 1 428 ? 43.761 73.325 -8.313 1.00 8.69 ? 428 MET A CB 1 ATOM 3352 C CG . MET A 1 428 ? 45.213 73.731 -7.974 1.00 9.32 ? 428 MET A CG 1 ATOM 3353 S SD . MET A 1 428 ? 45.130 75.086 -6.640 1.00 11.88 ? 428 MET A SD 1 ATOM 3354 C CE . MET A 1 428 ? 46.876 75.646 -6.555 1.00 8.44 ? 428 MET A CE 1 ATOM 3355 N N . ASP A 1 429 ? 43.333 70.200 -8.446 1.00 7.87 ? 429 ASP A N 1 ATOM 3356 C CA . ASP A 1 429 ? 43.657 68.860 -8.032 1.00 6.62 ? 429 ASP A CA 1 ATOM 3357 C C . ASP A 1 429 ? 44.240 68.073 -9.197 1.00 7.30 ? 429 ASP A C 1 ATOM 3358 O O . ASP A 1 429 ? 45.253 67.370 -9.052 1.00 7.12 ? 429 ASP A O 1 ATOM 3359 C CB . ASP A 1 429 ? 42.386 68.124 -7.480 1.00 7.88 ? 429 ASP A CB 1 ATOM 3360 C CG . ASP A 1 429 ? 42.657 66.647 -7.164 1.00 8.93 ? 429 ASP A CG 1 ATOM 3361 O OD1 . ASP A 1 429 ? 43.189 66.429 -6.092 1.00 6.73 ? 429 ASP A OD1 1 ATOM 3362 O OD2 . ASP A 1 429 ? 42.389 65.791 -8.014 1.00 6.23 ? 429 ASP A OD2 1 ATOM 3363 N N . ARG A 1 430 ? 43.649 68.169 -10.368 1.00 7.67 ? 430 ARG A N 1 ATOM 3364 C CA . ARG A 1 430 ? 44.120 67.386 -11.495 1.00 7.51 ? 430 ARG A CA 1 ATOM 3365 C C . ARG A 1 430 ? 45.423 67.960 -12.073 1.00 7.57 ? 430 ARG A C 1 ATOM 3366 O O . ARG A 1 430 ? 46.248 67.183 -12.605 1.00 8.35 ? 430 ARG A O 1 ATOM 3367 C CB . ARG A 1 430 ? 43.052 67.380 -12.611 1.00 7.46 ? 430 ARG A CB 1 ATOM 3368 C CG . ARG A 1 430 ? 41.703 66.754 -12.163 1.00 7.90 ? 430 ARG A CG 1 ATOM 3369 C CD . ARG A 1 430 ? 41.938 65.298 -11.812 1.00 8.22 ? 430 ARG A CD 1 ATOM 3370 N NE . ARG A 1 430 ? 40.698 64.487 -11.873 1.00 7.20 ? 430 ARG A NE 1 ATOM 3371 C CZ . ARG A 1 430 ? 40.020 64.123 -10.802 1.00 6.43 ? 430 ARG A CZ 1 ATOM 3372 N NH1 . ARG A 1 430 ? 40.440 64.447 -9.548 1.00 6.21 ? 430 ARG A NH1 1 ATOM 3373 N NH2 . ARG A 1 430 ? 38.856 63.442 -10.982 1.00 7.50 ? 430 ARG A NH2 1 ATOM 3374 N N . VAL A 1 431 ? 45.587 69.282 -11.987 1.00 8.09 ? 431 VAL A N 1 ATOM 3375 C CA . VAL A 1 431 ? 46.844 69.880 -12.487 1.00 7.42 ? 431 VAL A CA 1 ATOM 3376 C C . VAL A 1 431 ? 47.989 69.364 -11.540 1.00 9.81 ? 431 VAL A C 1 ATOM 3377 O O . VAL A 1 431 ? 48.996 68.845 -11.976 1.00 6.95 ? 431 VAL A O 1 ATOM 3378 C CB . VAL A 1 431 ? 46.735 71.406 -12.423 1.00 7.76 ? 431 VAL A CB 1 ATOM 3379 C CG1 . VAL A 1 431 ? 48.112 72.030 -12.721 1.00 8.90 ? 431 VAL A CG1 1 ATOM 3380 C CG2 . VAL A 1 431 ? 45.692 71.891 -13.419 1.00 9.38 ? 431 VAL A CG2 1 ATOM 3381 N N . LEU A 1 432 ? 47.777 69.414 -10.236 1.00 7.15 ? 432 LEU A N 1 ATOM 3382 C CA . LEU A 1 432 ? 48.838 69.015 -9.325 1.00 9.56 ? 432 LEU A CA 1 ATOM 3383 C C . LEU A 1 432 ? 49.029 67.499 -9.482 1.00 7.19 ? 432 LEU A C 1 ATOM 3384 O O . LEU A 1 432 ? 50.152 66.998 -9.377 1.00 6.84 ? 432 LEU A O 1 ATOM 3385 C CB . LEU A 1 432 ? 48.495 69.470 -7.909 1.00 8.64 ? 432 LEU A CB 1 ATOM 3386 C CG . LEU A 1 432 ? 49.491 69.043 -6.845 1.00 8.83 ? 432 LEU A CG 1 ATOM 3387 C CD1 . LEU A 1 432 ? 50.861 69.652 -7.083 1.00 9.10 ? 432 LEU A CD1 1 ATOM 3388 C CD2 . LEU A 1 432 ? 49.016 69.546 -5.521 1.00 8.65 ? 432 LEU A CD2 1 ATOM 3389 N N . MET A 1 433 ? 47.961 66.736 -9.673 1.00 6.42 ? 433 MET A N 1 ATOM 3390 C CA . MET A 1 433 ? 48.091 65.289 -9.839 1.00 7.03 ? 433 MET A CA 1 ATOM 3391 C C . MET A 1 433 ? 49.173 64.987 -10.899 1.00 7.01 ? 433 MET A C 1 ATOM 3392 O O . MET A 1 433 ? 50.054 64.150 -10.725 1.00 7.13 ? 433 MET A O 1 ATOM 3393 C CB . MET A 1 433 ? 46.784 64.694 -10.389 1.00 6.74 ? 433 MET A CB 1 ATOM 3394 C CG . MET A 1 433 ? 46.917 63.158 -10.632 1.00 6.43 ? 433 MET A CG 1 ATOM 3395 S SD . MET A 1 433 ? 45.343 62.503 -11.366 1.00 8.30 ? 433 MET A SD 1 ATOM 3396 C CE . MET A 1 433 ? 45.533 63.266 -12.983 1.00 12.64 ? 433 MET A CE 1 ATOM 3397 N N . HIS A 1 434 ? 49.064 65.663 -12.025 1.00 8.68 ? 434 HIS A N 1 ATOM 3398 C CA . HIS A 1 434 ? 49.997 65.465 -13.119 1.00 7.97 ? 434 HIS A CA 1 ATOM 3399 C C . HIS A 1 434 ? 51.394 65.976 -12.817 1.00 11.02 ? 434 HIS A C 1 ATOM 3400 O O . HIS A 1 434 ? 52.402 65.284 -13.155 1.00 6.93 ? 434 HIS A O 1 ATOM 3401 C CB . HIS A 1 434 ? 49.473 66.172 -14.355 1.00 9.45 ? 434 HIS A CB 1 ATOM 3402 C CG . HIS A 1 434 ? 50.478 66.209 -15.441 1.00 7.08 ? 434 HIS A CG 1 ATOM 3403 N ND1 . HIS A 1 434 ? 50.844 65.095 -16.157 1.00 9.32 ? 434 HIS A ND1 1 ATOM 3404 C CD2 . HIS A 1 434 ? 51.296 67.209 -15.835 1.00 8.49 ? 434 HIS A CD2 1 ATOM 3405 C CE1 . HIS A 1 434 ? 51.844 65.403 -16.969 1.00 9.31 ? 434 HIS A CE1 1 ATOM 3406 N NE2 . HIS A 1 434 ? 52.130 66.678 -16.804 1.00 10.17 ? 434 HIS A NE2 1 ATOM 3407 N N . TYR A 1 435 ? 51.470 67.154 -12.205 1.00 8.29 ? 435 TYR A N 1 ATOM 3408 C CA . TYR A 1 435 ? 52.795 67.739 -11.817 1.00 10.00 ? 435 TYR A CA 1 ATOM 3409 C C . TYR A 1 435 ? 53.514 66.787 -10.843 1.00 10.21 ? 435 TYR A C 1 ATOM 3410 O O . TYR A 1 435 ? 54.755 66.587 -10.964 1.00 10.72 ? 435 TYR A O 1 ATOM 3411 C CB . TYR A 1 435 ? 52.624 69.111 -11.151 1.00 11.19 ? 435 TYR A CB 1 ATOM 3412 C CG . TYR A 1 435 ? 52.554 70.271 -12.131 1.00 14.62 ? 435 TYR A CG 1 ATOM 3413 C CD1 . TYR A 1 435 ? 51.591 70.303 -13.153 1.00 15.52 ? 435 TYR A CD1 1 ATOM 3414 C CD2 . TYR A 1 435 ? 53.387 71.366 -11.980 1.00 18.38 ? 435 TYR A CD2 1 ATOM 3415 C CE1 . TYR A 1 435 ? 51.466 71.386 -13.996 1.00 16.65 ? 435 TYR A CE1 1 ATOM 3416 C CE2 . TYR A 1 435 ? 53.271 72.475 -12.813 1.00 19.96 ? 435 TYR A CE2 1 ATOM 3417 C CZ . TYR A 1 435 ? 52.306 72.469 -13.823 1.00 21.38 ? 435 TYR A CZ 1 ATOM 3418 O OH . TYR A 1 435 ? 52.197 73.559 -14.680 1.00 22.85 ? 435 TYR A OH 1 ATOM 3419 N N . VAL A 1 436 ? 52.793 66.186 -9.893 1.00 9.05 ? 436 VAL A N 1 ATOM 3420 C CA . VAL A 1 436 ? 53.480 65.268 -8.981 1.00 8.58 ? 436 VAL A CA 1 ATOM 3421 C C . VAL A 1 436 ? 54.010 64.065 -9.789 1.00 9.96 ? 436 VAL A C 1 ATOM 3422 O O . VAL A 1 436 ? 55.198 63.668 -9.626 1.00 8.98 ? 436 VAL A O 1 ATOM 3423 C CB . VAL A 1 436 ? 52.514 64.822 -7.844 1.00 8.36 ? 436 VAL A CB 1 ATOM 3424 C CG1 . VAL A 1 436 ? 53.020 63.565 -7.189 1.00 9.19 ? 436 VAL A CG1 1 ATOM 3425 C CG2 . VAL A 1 436 ? 52.369 65.972 -6.862 1.00 9.11 ? 436 VAL A CG2 1 ATOM 3426 N N . ARG A 1 437 ? 53.207 63.504 -10.680 1.00 8.40 ? 437 ARG A N 1 ATOM 3427 C CA . ARG A 1 437 ? 53.644 62.382 -11.456 1.00 8.93 ? 437 ARG A CA 1 ATOM 3428 C C . ARG A 1 437 ? 54.882 62.764 -12.249 1.00 8.23 ? 437 ARG A C 1 ATOM 3429 O O . ARG A 1 437 ? 55.887 62.073 -12.191 1.00 8.00 ? 437 ARG A O 1 ATOM 3430 C CB . ARG A 1 437 ? 52.545 61.827 -12.392 1.00 8.44 ? 437 ARG A CB 1 ATOM 3431 C CG . ARG A 1 437 ? 53.133 60.865 -13.441 1.00 8.83 ? 437 ARG A CG 1 ATOM 3432 C CD . ARG A 1 437 ? 52.027 60.357 -14.368 1.00 5.80 ? 437 ARG A CD 1 ATOM 3433 N NE . ARG A 1 437 ? 52.514 59.657 -15.516 1.00 7.57 ? 437 ARG A NE 1 ATOM 3434 C CZ . ARG A 1 437 ? 51.739 58.872 -16.240 1.00 9.53 ? 437 ARG A CZ 1 ATOM 3435 N NH1 . ARG A 1 437 ? 50.464 58.640 -15.917 1.00 8.68 ? 437 ARG A NH1 1 ATOM 3436 N NH2 . ARG A 1 437 ? 52.197 58.388 -17.390 1.00 9.86 ? 437 ARG A NH2 1 ATOM 3437 N N . ALA A 1 438 ? 54.850 63.904 -12.941 1.00 9.76 ? 438 ALA A N 1 ATOM 3438 C CA . ALA A 1 438 ? 55.969 64.345 -13.775 1.00 8.42 ? 438 ALA A CA 1 ATOM 3439 C C . ALA A 1 438 ? 57.231 64.626 -12.960 1.00 8.25 ? 438 ALA A C 1 ATOM 3440 O O . ALA A 1 438 ? 58.317 64.235 -13.433 1.00 7.87 ? 438 ALA A O 1 ATOM 3441 C CB . ALA A 1 438 ? 55.529 65.645 -14.581 1.00 8.25 ? 438 ALA A CB 1 ATOM 3442 N N . ALA A 1 439 ? 57.115 65.249 -11.771 1.00 7.26 ? 439 ALA A N 1 ATOM 3443 C CA . ALA A 1 439 ? 58.276 65.538 -10.970 1.00 7.94 ? 439 ALA A CA 1 ATOM 3444 C C . ALA A 1 439 ? 58.896 64.234 -10.443 1.00 8.04 ? 439 ALA A C 1 ATOM 3445 O O . ALA A 1 439 ? 60.113 64.112 -10.482 1.00 9.19 ? 439 ALA A O 1 ATOM 3446 C CB . ALA A 1 439 ? 57.947 66.502 -9.872 1.00 5.95 ? 439 ALA A CB 1 ATOM 3447 N N . GLU A 1 440 ? 58.094 63.278 -9.999 1.00 6.87 ? 440 GLU A N 1 ATOM 3448 C CA . GLU A 1 440 ? 58.644 62.036 -9.510 1.00 7.50 ? 440 GLU A CA 1 ATOM 3449 C C . GLU A 1 440 ? 59.282 61.254 -10.613 1.00 8.31 ? 440 GLU A C 1 ATOM 3450 O O . GLU A 1 440 ? 60.348 60.693 -10.379 1.00 10.49 ? 440 GLU A O 1 ATOM 3451 C CB . GLU A 1 440 ? 57.535 61.226 -8.796 1.00 7.41 ? 440 GLU A CB 1 ATOM 3452 C CG . GLU A 1 440 ? 57.051 61.841 -7.521 1.00 8.88 ? 440 GLU A CG 1 ATOM 3453 C CD . GLU A 1 440 ? 56.361 60.840 -6.605 1.00 12.05 ? 440 GLU A CD 1 ATOM 3454 O OE1 . GLU A 1 440 ? 55.227 60.418 -6.903 1.00 9.86 ? 440 GLU A OE1 1 ATOM 3455 O OE2 . GLU A 1 440 ? 57.009 60.495 -5.600 1.00 12.34 ? 440 GLU A OE2 1 ATOM 3456 N N . MET A 1 441 ? 58.708 61.179 -11.805 1.00 8.30 ? 441 MET A N 1 ATOM 3457 C CA . MET A 1 441 ? 59.285 60.468 -12.916 1.00 9.63 ? 441 MET A CA 1 ATOM 3458 C C . MET A 1 441 ? 60.552 61.096 -13.478 1.00 10.63 ? 441 MET A C 1 ATOM 3459 O O . MET A 1 441 ? 61.572 60.406 -13.675 1.00 9.73 ? 441 MET A O 1 ATOM 3460 C CB . MET A 1 441 ? 58.237 60.340 -14.017 1.00 9.03 ? 441 MET A CB 1 ATOM 3461 C CG . MET A 1 441 ? 58.706 59.609 -15.279 1.00 10.53 ? 441 MET A CG 1 ATOM 3462 S SD . MET A 1 441 ? 57.438 59.347 -16.565 1.00 9.25 ? 441 MET A SD 1 ATOM 3463 C CE . MET A 1 441 ? 56.357 58.064 -15.767 1.00 10.17 ? 441 MET A CE 1 ATOM 3464 N N . LEU A 1 442 ? 60.498 62.399 -13.725 1.00 10.97 ? 442 LEU A N 1 ATOM 3465 C CA . LEU A 1 442 ? 61.694 63.112 -14.243 1.00 11.75 ? 442 LEU A CA 1 ATOM 3466 C C . LEU A 1 442 ? 62.906 62.969 -13.342 1.00 12.03 ? 442 LEU A C 1 ATOM 3467 O O . LEU A 1 442 ? 64.026 62.814 -13.835 1.00 11.47 ? 442 LEU A O 1 ATOM 3468 C CB . LEU A 1 442 ? 61.407 64.633 -14.473 1.00 11.40 ? 442 LEU A CB 1 ATOM 3469 C CG . LEU A 1 442 ? 60.821 64.872 -15.877 1.00 11.73 ? 442 LEU A CG 1 ATOM 3470 C CD1 . LEU A 1 442 ? 60.261 66.247 -15.910 1.00 7.39 ? 442 LEU A CD1 1 ATOM 3471 C CD2 . LEU A 1 442 ? 61.905 64.638 -16.989 1.00 11.34 ? 442 LEU A CD2 1 ATOM 3472 N N . SER A 1 443 ? 62.694 62.995 -12.035 1.00 9.41 ? 443 SER A N 1 ATOM 3473 C CA . SER A 1 443 ? 63.824 62.923 -11.101 1.00 10.29 ? 443 SER A CA 1 ATOM 3474 C C . SER A 1 443 ? 64.200 61.516 -10.739 1.00 10.87 ? 443 SER A C 1 ATOM 3475 O O . SER A 1 443 ? 65.316 61.328 -10.207 1.00 11.01 ? 443 SER A O 1 ATOM 3476 C CB . SER A 1 443 ? 63.560 63.711 -9.837 1.00 8.40 ? 443 SER A CB 1 ATOM 3477 O OG . SER A 1 443 ? 62.420 63.249 -9.053 1.00 11.47 ? 443 SER A OG 1 ATOM 3478 N N . ALA A 1 444 ? 63.345 60.546 -11.041 1.00 11.18 ? 444 ALA A N 1 ATOM 3479 C CA . ALA A 1 444 ? 63.626 59.148 -10.724 1.00 11.45 ? 444 ALA A CA 1 ATOM 3480 C C . ALA A 1 444 ? 64.797 58.613 -11.513 1.00 10.80 ? 444 ALA A C 1 ATOM 3481 O O . ALA A 1 444 ? 65.448 57.649 -11.080 1.00 11.71 ? 444 ALA A O 1 ATOM 3482 C CB . ALA A 1 444 ? 62.462 58.292 -11.035 1.00 10.20 ? 444 ALA A CB 1 ATOM 3483 N N . TRP A 1 445 ? 65.076 59.195 -12.678 1.00 11.64 ? 445 TRP A N 1 ATOM 3484 C CA . TRP A 1 445 ? 66.130 58.680 -13.513 1.00 11.77 ? 445 TRP A CA 1 ATOM 3485 C C . TRP A 1 445 ? 67.536 58.664 -12.938 1.00 13.31 ? 445 TRP A C 1 ATOM 3486 O O . TRP A 1 445 ? 68.353 57.835 -13.395 1.00 12.98 ? 445 TRP A O 1 ATOM 3487 C CB . TRP A 1 445 ? 66.141 59.456 -14.854 1.00 11.25 ? 445 TRP A CB 1 ATOM 3488 C CG . TRP A 1 445 ? 64.869 59.241 -15.686 1.00 9.52 ? 445 TRP A CG 1 ATOM 3489 C CD1 . TRP A 1 445 ? 63.852 60.155 -15.852 1.00 12.18 ? 445 TRP A CD1 1 ATOM 3490 C CD2 . TRP A 1 445 ? 64.442 58.051 -16.378 1.00 10.07 ? 445 TRP A CD2 1 ATOM 3491 N NE1 . TRP A 1 445 ? 62.872 59.628 -16.592 1.00 9.30 ? 445 TRP A NE1 1 ATOM 3492 C CE2 . TRP A 1 445 ? 63.177 58.337 -16.935 1.00 10.52 ? 445 TRP A CE2 1 ATOM 3493 C CE3 . TRP A 1 445 ? 64.995 56.782 -16.565 1.00 11.89 ? 445 TRP A CE3 1 ATOM 3494 C CZ2 . TRP A 1 445 ? 62.465 57.414 -17.667 1.00 11.46 ? 445 TRP A CZ2 1 ATOM 3495 C CZ3 . TRP A 1 445 ? 64.282 55.838 -17.325 1.00 13.06 ? 445 TRP A CZ3 1 ATOM 3496 C CH2 . TRP A 1 445 ? 63.017 56.172 -17.870 1.00 13.97 ? 445 TRP A CH2 1 ATOM 3497 N N . HIS A 1 446 ? 67.762 59.534 -11.961 1.00 12.28 ? 446 HIS A N 1 ATOM 3498 C CA . HIS A 1 446 ? 69.073 59.651 -11.316 1.00 16.32 ? 446 HIS A CA 1 ATOM 3499 C C . HIS A 1 446 ? 68.917 59.687 -9.796 1.00 15.61 ? 446 HIS A C 1 ATOM 3500 O O . HIS A 1 446 ? 67.837 59.956 -9.263 1.00 16.84 ? 446 HIS A O 1 ATOM 3501 C CB . HIS A 1 446 ? 69.746 61.017 -11.598 1.00 16.54 ? 446 HIS A CB 1 ATOM 3502 C CG . HIS A 1 446 ? 70.214 61.227 -12.993 1.00 21.32 ? 446 HIS A CG 1 ATOM 3503 N ND1 . HIS A 1 446 ? 69.506 61.987 -13.905 1.00 21.56 ? 446 HIS A ND1 1 ATOM 3504 C CD2 . HIS A 1 446 ? 71.333 60.802 -13.630 1.00 21.37 ? 446 HIS A CD2 1 ATOM 3505 C CE1 . HIS A 1 446 ? 70.175 62.019 -15.047 1.00 23.86 ? 446 HIS A CE1 1 ATOM 3506 N NE2 . HIS A 1 446 ? 71.281 61.315 -14.909 1.00 21.45 ? 446 HIS A NE2 1 ATOM 3507 N N . SER A 1 447 ? 70.046 59.458 -9.114 1.00 15.61 ? 447 SER A N 1 ATOM 3508 C CA . SER A 1 447 ? 70.151 59.568 -7.668 1.00 15.08 ? 447 SER A CA 1 ATOM 3509 C C . SER A 1 447 ? 70.622 61.008 -7.499 1.00 15.81 ? 447 SER A C 1 ATOM 3510 O O . SER A 1 447 ? 71.478 61.489 -8.272 1.00 16.60 ? 447 SER A O 1 ATOM 3511 C CB A SER A 1 447 ? 71.243 58.635 -7.109 0.50 14.59 ? 447 SER A CB 1 ATOM 3512 C CB B SER A 1 447 ? 71.039 58.549 -6.982 0.50 17.21 ? 447 SER A CB 1 ATOM 3513 O OG A SER A 1 447 ? 70.721 57.757 -6.144 0.50 9.93 ? 447 SER A OG 1 ATOM 3514 O OG B SER A 1 447 ? 71.174 58.855 -5.614 0.50 20.44 ? 447 SER A OG 1 ATOM 3515 N N . TRP A 1 448 ? 70.084 61.701 -6.512 1.00 13.98 ? 448 TRP A N 1 ATOM 3516 C CA . TRP A 1 448 ? 70.457 63.074 -6.256 1.00 15.91 ? 448 TRP A CA 1 ATOM 3517 C C . TRP A 1 448 ? 71.141 63.262 -4.927 1.00 18.15 ? 448 TRP A C 1 ATOM 3518 O O . TRP A 1 448 ? 70.775 62.626 -3.924 1.00 17.09 ? 448 TRP A O 1 ATOM 3519 C CB . TRP A 1 448 ? 69.221 64.023 -6.302 1.00 14.77 ? 448 TRP A CB 1 ATOM 3520 C CG . TRP A 1 448 ? 68.511 64.058 -7.673 1.00 15.78 ? 448 TRP A CG 1 ATOM 3521 C CD1 . TRP A 1 448 ? 67.677 63.078 -8.195 1.00 11.78 ? 448 TRP A CD1 1 ATOM 3522 C CD2 . TRP A 1 448 ? 68.669 65.042 -8.698 1.00 15.65 ? 448 TRP A CD2 1 ATOM 3523 N NE1 . TRP A 1 448 ? 67.313 63.410 -9.494 1.00 15.06 ? 448 TRP A NE1 1 ATOM 3524 C CE2 . TRP A 1 448 ? 67.912 64.604 -9.817 1.00 13.55 ? 448 TRP A CE2 1 ATOM 3525 C CE3 . TRP A 1 448 ? 69.388 66.262 -8.786 1.00 16.26 ? 448 TRP A CE3 1 ATOM 3526 C CZ2 . TRP A 1 448 ? 67.852 65.316 -10.989 1.00 14.13 ? 448 TRP A CZ2 1 ATOM 3527 C CZ3 . TRP A 1 448 ? 69.319 66.972 -9.963 1.00 14.81 ? 448 TRP A CZ3 1 ATOM 3528 C CH2 . TRP A 1 448 ? 68.549 66.489 -11.055 1.00 16.98 ? 448 TRP A CH2 1 ATOM 3529 N N . ASP A 1 449 ? 72.113 64.171 -4.943 1.00 19.73 ? 449 ASP A N 1 ATOM 3530 C CA . ASP A 1 449 ? 72.863 64.583 -3.759 1.00 22.42 ? 449 ASP A CA 1 ATOM 3531 C C . ASP A 1 449 ? 71.854 65.214 -2.804 1.00 22.01 ? 449 ASP A C 1 ATOM 3532 O O . ASP A 1 449 ? 70.938 65.888 -3.230 1.00 20.68 ? 449 ASP A O 1 ATOM 3533 C CB . ASP A 1 449 ? 73.910 65.637 -4.181 1.00 24.35 ? 449 ASP A CB 1 ATOM 3534 C CG . ASP A 1 449 ? 74.810 66.099 -3.024 1.00 28.19 ? 449 ASP A CG 1 ATOM 3535 O OD1 . ASP A 1 449 ? 74.400 66.949 -2.211 1.00 28.34 ? 449 ASP A OD1 1 ATOM 3536 O OD2 . ASP A 1 449 ? 75.957 65.597 -2.923 1.00 30.66 ? 449 ASP A OD2 1 ATOM 3537 N N . GLY A 1 450 ? 72.042 65.024 -1.504 1.00 22.44 ? 450 GLY A N 1 ATOM 3538 C CA . GLY A 1 450 ? 71.121 65.596 -0.535 1.00 22.48 ? 450 GLY A CA 1 ATOM 3539 C C . GLY A 1 450 ? 70.984 67.084 -0.675 1.00 23.53 ? 450 GLY A C 1 ATOM 3540 O O . GLY A 1 450 ? 69.912 67.672 -0.446 1.00 22.68 ? 450 GLY A O 1 ATOM 3541 N N . MET A 1 451 ? 72.068 67.726 -1.062 1.00 22.04 ? 451 MET A N 1 ATOM 3542 C CA . MET A 1 451 ? 72.010 69.164 -1.220 1.00 25.17 ? 451 MET A CA 1 ATOM 3543 C C . MET A 1 451 ? 71.016 69.595 -2.300 1.00 22.48 ? 451 MET A C 1 ATOM 3544 O O . MET A 1 451 ? 70.663 70.756 -2.356 1.00 24.76 ? 451 MET A O 1 ATOM 3545 C CB . MET A 1 451 ? 73.413 69.700 -1.548 1.00 27.16 ? 451 MET A CB 1 ATOM 3546 C CG . MET A 1 451 ? 74.461 69.325 -0.506 1.00 33.76 ? 451 MET A CG 1 ATOM 3547 S SD . MET A 1 451 ? 74.997 70.694 0.613 1.00 41.42 ? 451 MET A SD 1 ATOM 3548 C CE . MET A 1 451 ? 73.534 70.889 1.743 1.00 37.41 ? 451 MET A CE 1 ATOM 3549 N N . ALA A 1 452 ? 70.579 68.685 -3.163 1.00 20.96 ? 452 ALA A N 1 ATOM 3550 C CA . ALA A 1 452 ? 69.622 69.091 -4.222 1.00 18.09 ? 452 ALA A CA 1 ATOM 3551 C C . ALA A 1 452 ? 68.186 69.202 -3.702 1.00 20.25 ? 452 ALA A C 1 ATOM 3552 O O . ALA A 1 452 ? 67.285 69.697 -4.415 1.00 20.43 ? 452 ALA A O 1 ATOM 3553 C CB . ALA A 1 452 ? 69.673 68.153 -5.342 1.00 19.46 ? 452 ALA A CB 1 ATOM 3554 N N . ARG A 1 453 ? 67.992 68.761 -2.462 1.00 18.86 ? 453 ARG A N 1 ATOM 3555 C CA . ARG A 1 453 ? 66.705 68.748 -1.763 1.00 18.79 ? 453 ARG A CA 1 ATOM 3556 C C . ARG A 1 453 ? 65.532 68.202 -2.618 1.00 15.48 ? 453 ARG A C 1 ATOM 3557 O O . ARG A 1 453 ? 64.381 68.696 -2.527 1.00 16.60 ? 453 ARG A O 1 ATOM 3558 C CB . ARG A 1 453 ? 66.389 70.140 -1.279 1.00 19.07 ? 453 ARG A CB 1 ATOM 3559 C CG . ARG A 1 453 ? 67.527 70.693 -0.438 1.00 22.22 ? 453 ARG A CG 1 ATOM 3560 C CD . ARG A 1 453 ? 67.377 72.174 -0.298 1.00 24.63 ? 453 ARG A CD 1 ATOM 3561 N NE . ARG A 1 453 ? 66.226 72.535 0.517 1.00 26.61 ? 453 ARG A NE 1 ATOM 3562 C CZ . ARG A 1 453 ? 65.740 73.776 0.607 1.00 28.72 ? 453 ARG A CZ 1 ATOM 3563 N NH1 . ARG A 1 453 ? 66.313 74.781 -0.079 1.00 29.69 ? 453 ARG A NH1 1 ATOM 3564 N NH2 . ARG A 1 453 ? 64.692 74.008 1.386 1.00 29.34 ? 453 ARG A NH2 1 ATOM 3565 N N . ILE A 1 454 ? 65.847 67.251 -3.480 1.00 14.87 ? 454 ILE A N 1 ATOM 3566 C CA . ILE A 1 454 ? 64.837 66.658 -4.331 1.00 13.33 ? 454 ILE A CA 1 ATOM 3567 C C . ILE A 1 454 ? 63.803 65.903 -3.433 1.00 14.09 ? 454 ILE A C 1 ATOM 3568 O O . ILE A 1 454 ? 62.571 66.098 -3.584 1.00 12.00 ? 454 ILE A O 1 ATOM 3569 C CB . ILE A 1 454 ? 65.469 65.688 -5.322 1.00 15.41 ? 454 ILE A CB 1 ATOM 3570 C CG1 . ILE A 1 454 ? 66.442 66.454 -6.240 1.00 15.27 ? 454 ILE A CG1 1 ATOM 3571 C CG2 . ILE A 1 454 ? 64.398 64.912 -6.131 1.00 14.25 ? 454 ILE A CG2 1 ATOM 3572 C CD1 . ILE A 1 454 ? 65.756 67.459 -7.180 1.00 14.19 ? 454 ILE A CD1 1 ATOM 3573 N N . GLU A 1 455 ? 64.270 65.005 -2.570 1.00 11.39 ? 455 GLU A N 1 ATOM 3574 C CA . GLU A 1 455 ? 63.358 64.239 -1.707 1.00 11.14 ? 455 GLU A CA 1 ATOM 3575 C C . GLU A 1 455 ? 62.458 65.129 -0.874 1.00 11.17 ? 455 GLU A C 1 ATOM 3576 O O . GLU A 1 455 ? 61.244 64.868 -0.717 1.00 11.27 ? 455 GLU A O 1 ATOM 3577 C CB . GLU A 1 455 ? 64.148 63.274 -0.818 1.00 13.38 ? 455 GLU A CB 1 ATOM 3578 C CG . GLU A 1 455 ? 64.677 62.072 -1.565 1.00 14.20 ? 455 GLU A CG 1 ATOM 3579 C CD . GLU A 1 455 ? 66.076 62.336 -2.168 1.00 13.85 ? 455 GLU A CD 1 ATOM 3580 O OE1 . GLU A 1 455 ? 66.567 63.468 -2.023 1.00 14.73 ? 455 GLU A OE1 1 ATOM 3581 O OE2 . GLU A 1 455 ? 66.663 61.381 -2.746 1.00 15.20 ? 455 GLU A OE2 1 ATOM 3582 N N . GLU A 1 456 ? 63.002 66.190 -0.308 1.00 11.64 ? 456 GLU A N 1 ATOM 3583 C CA . GLU A 1 456 ? 62.301 67.133 0.513 1.00 13.08 ? 456 GLU A CA 1 ATOM 3584 C C . GLU A 1 456 ? 61.135 67.791 -0.287 1.00 12.54 ? 456 GLU A C 1 ATOM 3585 O O . GLU A 1 456 ? 59.958 67.815 0.135 1.00 13.46 ? 456 GLU A O 1 ATOM 3586 C CB . GLU A 1 456 ? 63.333 68.179 0.927 1.00 16.35 ? 456 GLU A CB 1 ATOM 3587 C CG . GLU A 1 456 ? 62.793 69.232 1.767 1.00 21.82 ? 456 GLU A CG 1 ATOM 3588 C CD . GLU A 1 456 ? 63.724 70.450 1.877 1.00 25.26 ? 456 GLU A CD 1 ATOM 3589 O OE1 . GLU A 1 456 ? 64.958 70.319 1.667 1.00 27.52 ? 456 GLU A OE1 1 ATOM 3590 O OE2 . GLU A 1 456 ? 63.214 71.550 2.193 1.00 27.38 ? 456 GLU A OE2 1 ATOM 3591 N N . ARG A 1 457 ? 61.472 68.303 -1.458 1.00 12.90 ? 457 ARG A N 1 ATOM 3592 C CA . ARG A 1 457 ? 60.427 68.975 -2.271 1.00 12.97 ? 457 ARG A CA 1 ATOM 3593 C C . ARG A 1 457 ? 59.310 67.988 -2.708 1.00 11.67 ? 457 ARG A C 1 ATOM 3594 O O . ARG A 1 457 ? 58.121 68.346 -2.715 1.00 12.82 ? 457 ARG A O 1 ATOM 3595 C CB . ARG A 1 457 ? 61.033 69.635 -3.506 1.00 13.73 ? 457 ARG A CB 1 ATOM 3596 C CG . ARG A 1 457 ? 61.365 71.101 -3.314 1.00 16.90 ? 457 ARG A CG 1 ATOM 3597 C CD . ARG A 1 457 ? 62.354 71.283 -2.245 1.00 19.01 ? 457 ARG A CD 1 ATOM 3598 N NE . ARG A 1 457 ? 62.740 72.688 -2.109 1.00 21.29 ? 457 ARG A NE 1 ATOM 3599 C CZ . ARG A 1 457 ? 63.737 73.280 -2.789 1.00 23.03 ? 457 ARG A CZ 1 ATOM 3600 N NH1 . ARG A 1 457 ? 64.461 72.620 -3.682 1.00 21.47 ? 457 ARG A NH1 1 ATOM 3601 N NH2 . ARG A 1 457 ? 64.057 74.535 -2.523 1.00 23.71 ? 457 ARG A NH2 1 ATOM 3602 N N . LEU A 1 458 ? 59.708 66.782 -3.114 1.00 11.71 ? 458 LEU A N 1 ATOM 3603 C CA . LEU A 1 458 ? 58.725 65.771 -3.540 1.00 10.11 ? 458 LEU A CA 1 ATOM 3604 C C . LEU A 1 458 ? 57.863 65.320 -2.387 1.00 10.87 ? 458 LEU A C 1 ATOM 3605 O O . LEU A 1 458 ? 56.677 65.085 -2.616 1.00 9.80 ? 458 LEU A O 1 ATOM 3606 C CB . LEU A 1 458 ? 59.378 64.562 -4.172 1.00 10.23 ? 458 LEU A CB 1 ATOM 3607 C CG . LEU A 1 458 ? 60.083 64.964 -5.497 1.00 11.72 ? 458 LEU A CG 1 ATOM 3608 C CD1 . LEU A 1 458 ? 60.896 63.735 -5.977 1.00 11.00 ? 458 LEU A CD1 1 ATOM 3609 C CD2 . LEU A 1 458 ? 59.048 65.454 -6.645 1.00 11.06 ? 458 LEU A CD2 1 ATOM 3610 N N . GLU A 1 459 ? 58.385 65.236 -1.157 1.00 8.92 ? 459 GLU A N 1 ATOM 3611 C CA . GLU A 1 459 ? 57.591 64.797 -0.020 1.00 11.23 ? 459 GLU A CA 1 ATOM 3612 C C . GLU A 1 459 ? 56.571 65.835 0.239 1.00 11.66 ? 459 GLU A C 1 ATOM 3613 O O . GLU A 1 459 ? 55.404 65.506 0.476 1.00 10.49 ? 459 GLU A O 1 ATOM 3614 C CB . GLU A 1 459 ? 58.464 64.567 1.244 1.00 13.46 ? 459 GLU A CB 1 ATOM 3615 C CG . GLU A 1 459 ? 57.671 64.052 2.456 1.00 15.82 ? 459 GLU A CG 1 ATOM 3616 C CD . GLU A 1 459 ? 58.588 63.442 3.518 1.00 18.64 ? 459 GLU A CD 1 ATOM 3617 O OE1 . GLU A 1 459 ? 59.197 64.254 4.260 1.00 20.72 ? 459 GLU A OE1 1 ATOM 3618 O OE2 . GLU A 1 459 ? 58.706 62.173 3.594 1.00 21.85 ? 459 GLU A OE2 1 ATOM 3619 N N . GLN A 1 460 ? 56.950 67.102 0.185 1.00 10.96 ? 460 GLN A N 1 ATOM 3620 C CA . GLN A 1 460 ? 56.011 68.206 0.429 1.00 11.69 ? 460 GLN A CA 1 ATOM 3621 C C . GLN A 1 460 ? 54.910 68.162 -0.643 1.00 8.33 ? 460 GLN A C 1 ATOM 3622 O O . GLN A 1 460 ? 53.711 68.273 -0.316 1.00 10.80 ? 460 GLN A O 1 ATOM 3623 C CB . GLN A 1 460 ? 56.785 69.544 0.358 1.00 14.34 ? 460 GLN A CB 1 ATOM 3624 C CG . GLN A 1 460 ? 55.867 70.745 0.494 1.00 20.03 ? 460 GLN A CG 1 ATOM 3625 C CD . GLN A 1 460 ? 56.593 72.072 0.287 1.00 23.78 ? 460 GLN A CD 1 ATOM 3626 O OE1 . GLN A 1 460 ? 57.673 72.112 -0.308 1.00 27.43 ? 460 GLN A OE1 1 ATOM 3627 N NE2 . GLN A 1 460 ? 55.989 73.159 0.748 1.00 28.56 ? 460 GLN A NE2 1 ATOM 3628 N N . ALA A 1 461 ? 55.291 67.933 -1.895 1.00 10.61 ? 461 ALA A N 1 ATOM 3629 C CA . ALA A 1 461 ? 54.276 67.954 -2.978 1.00 9.67 ? 461 ALA A CA 1 ATOM 3630 C C . ALA A 1 461 ? 53.279 66.819 -2.795 1.00 10.50 ? 461 ALA A C 1 ATOM 3631 O O . ALA A 1 461 ? 52.064 67.047 -2.844 1.00 9.71 ? 461 ALA A O 1 ATOM 3632 C CB . ALA A 1 461 ? 54.931 67.893 -4.405 1.00 10.97 ? 461 ALA A CB 1 ATOM 3633 N N . ARG A 1 462 ? 53.773 65.616 -2.551 1.00 9.13 ? 462 ARG A N 1 ATOM 3634 C CA . ARG A 1 462 ? 52.920 64.476 -2.306 1.00 6.91 ? 462 ARG A CA 1 ATOM 3635 C C . ARG A 1 462 ? 52.021 64.722 -1.083 1.00 8.26 ? 462 ARG A C 1 ATOM 3636 O O . ARG A 1 462 ? 50.839 64.366 -1.108 1.00 8.34 ? 462 ARG A O 1 ATOM 3637 C CB . ARG A 1 462 ? 53.739 63.196 -2.061 1.00 8.30 ? 462 ARG A CB 1 ATOM 3638 C CG . ARG A 1 462 ? 54.536 62.713 -3.264 1.00 7.09 ? 462 ARG A CG 1 ATOM 3639 C CD . ARG A 1 462 ? 54.899 61.247 -2.982 1.00 8.90 ? 462 ARG A CD 1 ATOM 3640 N NE . ARG A 1 462 ? 55.820 61.091 -1.824 1.00 9.58 ? 462 ARG A NE 1 ATOM 3641 C CZ . ARG A 1 462 ? 57.154 61.276 -1.883 1.00 11.70 ? 462 ARG A CZ 1 ATOM 3642 N NH1 . ARG A 1 462 ? 57.773 61.589 -3.038 1.00 10.61 ? 462 ARG A NH1 1 ATOM 3643 N NH2 . ARG A 1 462 ? 57.857 61.224 -0.764 1.00 12.80 ? 462 ARG A NH2 1 ATOM 3644 N N . ARG A 1 463 ? 52.532 65.270 0.015 1.00 7.07 ? 463 ARG A N 1 ATOM 3645 C CA . ARG A 1 463 ? 51.717 65.477 1.200 1.00 8.09 ? 463 ARG A CA 1 ATOM 3646 C C . ARG A 1 463 ? 50.666 66.548 1.005 1.00 8.62 ? 463 ARG A C 1 ATOM 3647 O O . ARG A 1 463 ? 49.522 66.380 1.491 1.00 9.76 ? 463 ARG A O 1 ATOM 3648 C CB . ARG A 1 463 ? 52.565 65.697 2.456 1.00 10.90 ? 463 ARG A CB 1 ATOM 3649 C CG . ARG A 1 463 ? 53.318 64.405 2.780 1.00 10.58 ? 463 ARG A CG 1 ATOM 3650 C CD . ARG A 1 463 ? 54.333 64.603 3.931 1.00 10.68 ? 463 ARG A CD 1 ATOM 3651 N NE . ARG A 1 463 ? 54.832 63.254 4.268 1.00 12.58 ? 463 ARG A NE 1 ATOM 3652 C CZ . ARG A 1 463 ? 55.550 62.975 5.352 1.00 15.88 ? 463 ARG A CZ 1 ATOM 3653 N NH1 . ARG A 1 463 ? 55.859 63.940 6.179 1.00 16.31 ? 463 ARG A NH1 1 ATOM 3654 N NH2 . ARG A 1 463 ? 55.930 61.710 5.589 1.00 13.42 ? 463 ARG A NH2 1 ATOM 3655 N N . GLU A 1 464 ? 50.933 67.603 0.237 1.00 9.36 ? 464 GLU A N 1 ATOM 3656 C CA . GLU A 1 464 ? 49.881 68.595 0.133 1.00 9.94 ? 464 GLU A CA 1 ATOM 3657 C C . GLU A 1 464 ? 48.801 68.088 -0.812 1.00 7.64 ? 464 GLU A C 1 ATOM 3658 O O . GLU A 1 464 ? 47.608 68.338 -0.563 1.00 8.72 ? 464 GLU A O 1 ATOM 3659 C CB . GLU A 1 464 ? 50.406 69.948 -0.372 1.00 10.17 ? 464 GLU A CB 1 ATOM 3660 C CG . GLU A 1 464 ? 51.611 70.465 0.383 1.00 13.22 ? 464 GLU A CG 1 ATOM 3661 C CD . GLU A 1 464 ? 51.287 70.999 1.740 1.00 15.69 ? 464 GLU A CD 1 ATOM 3662 O OE1 . GLU A 1 464 ? 50.272 70.640 2.328 1.00 16.07 ? 464 GLU A OE1 1 ATOM 3663 O OE2 . GLU A 1 464 ? 52.087 71.815 2.254 1.00 21.86 ? 464 GLU A OE2 1 ATOM 3664 N N . LEU A 1 465 ? 49.154 67.325 -1.832 1.00 9.25 ? 465 LEU A N 1 ATOM 3665 C CA . LEU A 1 465 ? 48.137 66.774 -2.734 1.00 7.83 ? 465 LEU A CA 1 ATOM 3666 C C . LEU A 1 465 ? 47.338 65.701 -1.986 1.00 8.87 ? 465 LEU A C 1 ATOM 3667 O O . LEU A 1 465 ? 46.121 65.627 -2.150 1.00 8.19 ? 465 LEU A O 1 ATOM 3668 C CB . LEU A 1 465 ? 48.758 66.145 -3.943 1.00 8.97 ? 465 LEU A CB 1 ATOM 3669 C CG . LEU A 1 465 ? 47.810 65.528 -4.986 1.00 9.18 ? 465 LEU A CG 1 ATOM 3670 C CD1 . LEU A 1 465 ? 46.754 66.617 -5.522 1.00 8.92 ? 465 LEU A CD1 1 ATOM 3671 C CD2 . LEU A 1 465 ? 48.659 64.998 -6.202 1.00 7.51 ? 465 LEU A CD2 1 ATOM 3672 N N . SER A 1 466 ? 48.026 64.876 -1.172 1.00 9.48 ? 466 SER A N 1 ATOM 3673 C CA . SER A 1 466 ? 47.378 63.827 -0.363 1.00 9.02 ? 466 SER A CA 1 ATOM 3674 C C . SER A 1 466 ? 46.400 64.447 0.594 1.00 7.37 ? 466 SER A C 1 ATOM 3675 O O . SER A 1 466 ? 45.263 63.946 0.717 1.00 8.10 ? 466 SER A O 1 ATOM 3676 C CB . SER A 1 466 ? 48.438 63.017 0.421 1.00 8.55 ? 466 SER A CB 1 ATOM 3677 O OG . SER A 1 466 ? 49.197 62.323 -0.562 1.00 9.50 ? 466 SER A OG 1 ATOM 3678 N N . LEU A 1 467 ? 46.781 65.558 1.224 1.00 5.73 ? 467 LEU A N 1 ATOM 3679 C CA . LEU A 1 467 ? 45.915 66.209 2.203 1.00 6.99 ? 467 LEU A CA 1 ATOM 3680 C C . LEU A 1 467 ? 44.625 66.667 1.516 1.00 6.85 ? 467 LEU A C 1 ATOM 3681 O O . LEU A 1 467 ? 43.518 66.505 2.056 1.00 6.86 ? 467 LEU A O 1 ATOM 3682 C CB . LEU A 1 467 ? 46.617 67.434 2.840 1.00 9.48 ? 467 LEU A CB 1 ATOM 3683 C CG . LEU A 1 467 ? 45.785 68.095 3.928 1.00 11.68 ? 467 LEU A CG 1 ATOM 3684 C CD1 . LEU A 1 467 ? 45.898 67.307 5.213 1.00 13.31 ? 467 LEU A CD1 1 ATOM 3685 C CD2 . LEU A 1 467 ? 46.345 69.557 4.204 1.00 13.49 ? 467 LEU A CD2 1 ATOM 3686 N N . PHE A 1 468 ? 44.736 67.118 0.257 1.00 7.28 ? 468 PHE A N 1 ATOM 3687 C CA . PHE A 1 468 ? 43.562 67.673 -0.458 1.00 7.64 ? 468 PHE A CA 1 ATOM 3688 C C . PHE A 1 468 ? 42.581 66.558 -0.868 1.00 7.74 ? 468 PHE A C 1 ATOM 3689 O O . PHE A 1 468 ? 41.428 66.857 -1.200 1.00 7.52 ? 468 PHE A O 1 ATOM 3690 C CB . PHE A 1 468 ? 43.967 68.482 -1.699 1.00 8.17 ? 468 PHE A CB 1 ATOM 3691 C CG . PHE A 1 468 ? 42.835 69.311 -2.268 1.00 6.22 ? 468 PHE A CG 1 ATOM 3692 C CD1 . PHE A 1 468 ? 42.199 70.259 -1.480 1.00 8.29 ? 468 PHE A CD1 1 ATOM 3693 C CD2 . PHE A 1 468 ? 42.399 69.107 -3.555 1.00 8.04 ? 468 PHE A CD2 1 ATOM 3694 C CE1 . PHE A 1 468 ? 41.066 70.992 -2.041 1.00 6.21 ? 468 PHE A CE1 1 ATOM 3695 C CE2 . PHE A 1 468 ? 41.299 69.850 -4.092 1.00 6.86 ? 468 PHE A CE2 1 ATOM 3696 C CZ . PHE A 1 468 ? 40.643 70.769 -3.313 1.00 9.55 ? 468 PHE A CZ 1 ATOM 3697 N N . GLN A 1 469 ? 43.003 65.288 -0.860 1.00 6.64 ? 469 GLN A N 1 ATOM 3698 C CA . GLN A 1 469 ? 42.037 64.219 -1.095 1.00 6.72 ? 469 GLN A CA 1 ATOM 3699 C C . GLN A 1 469 ? 41.017 64.027 0.041 1.00 7.77 ? 469 GLN A C 1 ATOM 3700 O O . GLN A 1 469 ? 40.062 63.269 -0.174 1.00 6.86 ? 469 GLN A O 1 ATOM 3701 C CB . GLN A 1 469 ? 42.738 62.883 -1.277 1.00 7.60 ? 469 GLN A CB 1 ATOM 3702 C CG . GLN A 1 469 ? 43.848 62.925 -2.390 1.00 5.95 ? 469 GLN A CG 1 ATOM 3703 C CD . GLN A 1 469 ? 43.366 63.547 -3.672 1.00 9.05 ? 469 GLN A CD 1 ATOM 3704 O OE1 . GLN A 1 469 ? 42.391 63.065 -4.243 1.00 7.61 ? 469 GLN A OE1 1 ATOM 3705 N NE2 . GLN A 1 469 ? 44.008 64.633 -4.131 1.00 7.43 ? 469 GLN A NE2 1 ATOM 3706 N N . HIS A 1 470 ? 41.206 64.666 1.212 1.00 5.58 ? 470 HIS A N 1 ATOM 3707 C CA . HIS A 1 470 ? 40.284 64.595 2.362 1.00 5.10 ? 470 HIS A CA 1 ATOM 3708 C C . HIS A 1 470 ? 38.859 64.871 1.848 1.00 5.74 ? 470 HIS A C 1 ATOM 3709 O O . HIS A 1 470 ? 38.659 65.627 0.903 1.00 5.99 ? 470 HIS A O 1 ATOM 3710 C CB . HIS A 1 470 ? 40.707 65.655 3.400 1.00 6.97 ? 470 HIS A CB 1 ATOM 3711 C CG . HIS A 1 470 ? 39.739 65.824 4.507 1.00 7.46 ? 470 HIS A CG 1 ATOM 3712 N ND1 . HIS A 1 470 ? 39.140 64.755 5.153 1.00 6.33 ? 470 HIS A ND1 1 ATOM 3713 C CD2 . HIS A 1 470 ? 39.228 66.946 5.063 1.00 9.17 ? 470 HIS A CD2 1 ATOM 3714 C CE1 . HIS A 1 470 ? 38.291 65.231 6.047 1.00 7.08 ? 470 HIS A CE1 1 ATOM 3715 N NE2 . HIS A 1 470 ? 38.312 66.554 5.993 1.00 7.93 ? 470 HIS A NE2 1 ATOM 3716 N N . HIS A 1 471 ? 37.880 64.222 2.499 1.00 5.60 ? 471 HIS A N 1 ATOM 3717 C CA . HIS A 1 471 ? 36.464 64.369 2.168 1.00 6.97 ? 471 HIS A CA 1 ATOM 3718 C C . HIS A 1 471 ? 35.874 65.763 2.412 1.00 9.35 ? 471 HIS A C 1 ATOM 3719 O O . HIS A 1 471 ? 34.659 65.918 2.273 1.00 9.41 ? 471 HIS A O 1 ATOM 3720 C CB . HIS A 1 471 ? 35.580 63.245 2.783 1.00 7.72 ? 471 HIS A CB 1 ATOM 3721 C CG . HIS A 1 471 ? 35.659 63.146 4.270 1.00 4.99 ? 471 HIS A CG 1 ATOM 3722 N ND1 . HIS A 1 471 ? 36.656 62.429 4.921 1.00 5.27 ? 471 HIS A ND1 1 ATOM 3723 C CD2 . HIS A 1 471 ? 34.879 63.682 5.242 1.00 6.96 ? 471 HIS A CD2 1 ATOM 3724 C CE1 . HIS A 1 471 ? 36.498 62.554 6.221 1.00 6.21 ? 471 HIS A CE1 1 ATOM 3725 N NE2 . HIS A 1 471 ? 35.421 63.301 6.434 1.00 5.20 ? 471 HIS A NE2 1 ATOM 3726 N N . ASP A 1 472 ? 36.712 66.760 2.818 1.00 8.82 ? 472 ASP A N 1 ATOM 3727 C CA . ASP A 1 472 ? 36.255 68.158 2.870 1.00 8.07 ? 472 ASP A CA 1 ATOM 3728 C C . ASP A 1 472 ? 37.209 69.011 2.054 1.00 7.84 ? 472 ASP A C 1 ATOM 3729 O O . ASP A 1 472 ? 37.056 70.220 2.054 1.00 8.96 ? 472 ASP A O 1 ATOM 3730 C CB . ASP A 1 472 ? 36.160 68.725 4.305 1.00 7.28 ? 472 ASP A CB 1 ATOM 3731 C CG . ASP A 1 472 ? 35.125 67.970 5.154 1.00 8.98 ? 472 ASP A CG 1 ATOM 3732 O OD1 . ASP A 1 472 ? 33.929 68.027 4.713 1.00 9.30 ? 472 ASP A OD1 1 ATOM 3733 O OD2 . ASP A 1 472 ? 35.500 67.344 6.134 1.00 7.76 ? 472 ASP A OD2 1 ATOM 3734 N N . GLY A 1 473 ? 38.166 68.381 1.354 1.00 6.82 ? 473 GLY A N 1 ATOM 3735 C CA . GLY A 1 473 ? 39.084 69.117 0.520 1.00 7.05 ? 473 GLY A CA 1 ATOM 3736 C C . GLY A 1 473 ? 38.581 69.199 -0.883 1.00 8.41 ? 473 GLY A C 1 ATOM 3737 O O . GLY A 1 473 ? 37.836 70.141 -1.250 1.00 6.72 ? 473 GLY A O 1 ATOM 3738 N N . ILE A 1 474 ? 38.931 68.210 -1.689 1.00 7.24 ? 474 ILE A N 1 ATOM 3739 C CA . ILE A 1 474 ? 38.485 68.230 -3.079 1.00 6.86 ? 474 ILE A CA 1 ATOM 3740 C C . ILE A 1 474 ? 36.951 68.367 -3.213 1.00 7.21 ? 474 ILE A C 1 ATOM 3741 O O . ILE A 1 474 ? 36.448 68.833 -4.209 1.00 9.36 ? 474 ILE A O 1 ATOM 3742 C CB . ILE A 1 474 ? 39.075 66.938 -3.791 1.00 5.33 ? 474 ILE A CB 1 ATOM 3743 C CG1 . ILE A 1 474 ? 38.908 67.015 -5.322 1.00 7.60 ? 474 ILE A CG1 1 ATOM 3744 C CG2 . ILE A 1 474 ? 38.486 65.636 -3.164 1.00 6.21 ? 474 ILE A CG2 1 ATOM 3745 C CD1 . ILE A 1 474 ? 39.581 65.823 -6.098 1.00 8.43 ? 474 ILE A CD1 1 ATOM 3746 N N . THR A 1 475 ? 36.236 67.926 -2.222 1.00 7.56 ? 475 THR A N 1 ATOM 3747 C CA . THR A 1 475 ? 34.772 68.006 -2.229 1.00 6.50 ? 475 THR A CA 1 ATOM 3748 C C . THR A 1 475 ? 34.228 69.454 -2.226 1.00 8.47 ? 475 THR A C 1 ATOM 3749 O O . THR A 1 475 ? 33.054 69.650 -2.539 1.00 8.71 ? 475 THR A O 1 ATOM 3750 C CB . THR A 1 475 ? 34.164 67.359 -0.919 1.00 7.64 ? 475 THR A CB 1 ATOM 3751 O OG1 . THR A 1 475 ? 34.718 68.038 0.211 1.00 8.14 ? 475 THR A OG1 1 ATOM 3752 C CG2 . THR A 1 475 ? 34.534 65.830 -0.853 1.00 6.03 ? 475 THR A CG2 1 ATOM 3753 N N . GLY A 1 476 ? 35.018 70.416 -1.788 1.00 7.70 ? 476 GLY A N 1 ATOM 3754 C CA . GLY A 1 476 ? 34.493 71.806 -1.750 1.00 7.60 ? 476 GLY A CA 1 ATOM 3755 C C . GLY A 1 476 ? 33.514 71.969 -0.605 1.00 9.01 ? 476 GLY A C 1 ATOM 3756 O O . GLY A 1 476 ? 32.624 72.823 -0.717 1.00 8.31 ? 476 GLY A O 1 ATOM 3757 N N . THR A 1 477 ? 33.670 71.199 0.487 1.00 8.33 ? 477 THR A N 1 ATOM 3758 C CA . THR A 1 477 ? 32.753 71.328 1.597 1.00 7.14 ? 477 THR A CA 1 ATOM 3759 C C . THR A 1 477 ? 33.382 71.954 2.862 1.00 9.28 ? 477 THR A C 1 ATOM 3760 O O . THR A 1 477 ? 32.906 71.826 3.967 1.00 8.80 ? 477 THR A O 1 ATOM 3761 C CB . THR A 1 477 ? 32.096 69.946 1.937 1.00 5.80 ? 477 THR A CB 1 ATOM 3762 O OG1 . THR A 1 477 ? 33.153 69.000 2.222 1.00 9.17 ? 477 THR A OG1 1 ATOM 3763 C CG2 . THR A 1 477 ? 31.250 69.493 0.789 1.00 6.25 ? 477 THR A CG2 1 ATOM 3764 N N . ALA A 1 478 ? 34.503 72.674 2.689 1.00 9.18 ? 478 ALA A N 1 ATOM 3765 C CA . ALA A 1 478 ? 35.107 73.307 3.846 1.00 9.61 ? 478 ALA A CA 1 ATOM 3766 C C . ALA A 1 478 ? 34.753 74.787 3.954 1.00 11.27 ? 478 ALA A C 1 ATOM 3767 O O . ALA A 1 478 ? 34.246 75.400 3.039 1.00 8.98 ? 478 ALA A O 1 ATOM 3768 C CB . ALA A 1 478 ? 36.688 73.154 3.860 1.00 9.48 ? 478 ALA A CB 1 ATOM 3769 N N . LYS A 1 479 ? 35.090 75.392 5.088 1.00 9.90 ? 479 LYS A N 1 ATOM 3770 C CA . LYS A 1 479 ? 34.834 76.819 5.193 1.00 12.46 ? 479 LYS A CA 1 ATOM 3771 C C . LYS A 1 479 ? 35.808 77.604 4.305 1.00 12.74 ? 479 LYS A C 1 ATOM 3772 O O . LYS A 1 479 ? 36.910 77.146 3.989 1.00 11.65 ? 479 LYS A O 1 ATOM 3773 C CB . LYS A 1 479 ? 34.976 77.254 6.639 1.00 13.38 ? 479 LYS A CB 1 ATOM 3774 C CG . LYS A 1 479 ? 33.724 76.851 7.451 1.00 18.16 ? 479 LYS A CG 1 ATOM 3775 C CD . LYS A 1 479 ? 33.750 77.316 8.890 1.00 21.22 ? 479 LYS A CD 1 ATOM 3776 C CE . LYS A 1 479 ? 32.950 78.579 9.075 1.00 26.06 ? 479 LYS A CE 1 ATOM 3777 N NZ . LYS A 1 479 ? 31.457 78.414 9.138 1.00 25.96 ? 479 LYS A NZ 1 ATOM 3778 N N . THR A 1 480 ? 35.391 78.798 3.932 1.00 14.71 ? 480 THR A N 1 ATOM 3779 C CA . THR A 1 480 ? 36.197 79.648 3.084 1.00 15.82 ? 480 THR A CA 1 ATOM 3780 C C . THR A 1 480 ? 37.679 79.757 3.437 1.00 12.39 ? 480 THR A C 1 ATOM 3781 O O . THR A 1 480 ? 38.530 79.623 2.590 1.00 12.06 ? 480 THR A O 1 ATOM 3782 C CB . THR A 1 480 ? 35.615 81.097 3.076 1.00 17.80 ? 480 THR A CB 1 ATOM 3783 O OG1 . THR A 1 480 ? 34.239 81.055 2.676 1.00 20.07 ? 480 THR A OG1 1 ATOM 3784 C CG2 . THR A 1 480 ? 36.394 81.979 2.100 1.00 18.37 ? 480 THR A CG2 1 ATOM 3785 N N . HIS A 1 481 ? 37.991 80.022 4.684 1.00 12.29 ? 481 HIS A N 1 ATOM 3786 C CA . HIS A 1 481 ? 39.411 80.171 5.022 1.00 12.29 ? 481 HIS A CA 1 ATOM 3787 C C . HIS A 1 481 ? 40.147 78.870 4.955 1.00 12.52 ? 481 HIS A C 1 ATOM 3788 O O . HIS A 1 481 ? 41.355 78.844 4.902 1.00 13.23 ? 481 HIS A O 1 ATOM 3789 C CB . HIS A 1 481 ? 39.575 80.869 6.402 1.00 13.98 ? 481 HIS A CB 1 ATOM 3790 C CG . HIS A 1 481 ? 39.519 79.980 7.603 1.00 15.18 ? 481 HIS A CG 1 ATOM 3791 N ND1 . HIS A 1 481 ? 38.334 79.601 8.208 1.00 16.38 ? 481 HIS A ND1 1 ATOM 3792 C CD2 . HIS A 1 481 ? 40.516 79.472 8.370 1.00 13.72 ? 481 HIS A CD2 1 ATOM 3793 C CE1 . HIS A 1 481 ? 38.600 78.915 9.312 1.00 17.41 ? 481 HIS A CE1 1 ATOM 3794 N NE2 . HIS A 1 481 ? 39.920 78.828 9.433 1.00 14.64 ? 481 HIS A NE2 1 ATOM 3795 N N . VAL A 1 482 ? 39.411 77.758 5.022 1.00 13.32 ? 482 VAL A N 1 ATOM 3796 C CA . VAL A 1 482 ? 40.088 76.441 4.908 1.00 10.81 ? 482 VAL A CA 1 ATOM 3797 C C . VAL A 1 482 ? 40.355 76.152 3.461 1.00 11.29 ? 482 VAL A C 1 ATOM 3798 O O . VAL A 1 482 ? 41.397 75.643 3.164 1.00 8.41 ? 482 VAL A O 1 ATOM 3799 C CB . VAL A 1 482 ? 39.214 75.319 5.508 1.00 10.84 ? 482 VAL A CB 1 ATOM 3800 C CG1 . VAL A 1 482 ? 39.966 73.948 5.516 1.00 8.13 ? 482 VAL A CG1 1 ATOM 3801 C CG2 . VAL A 1 482 ? 38.944 75.684 6.991 1.00 9.46 ? 482 VAL A CG2 1 ATOM 3802 N N . VAL A 1 483 ? 39.437 76.470 2.557 1.00 8.36 ? 483 VAL A N 1 ATOM 3803 C CA . VAL A 1 483 ? 39.703 76.281 1.120 1.00 9.85 ? 483 VAL A CA 1 ATOM 3804 C C . VAL A 1 483 ? 40.950 77.124 0.808 1.00 11.93 ? 483 VAL A C 1 ATOM 3805 O O . VAL A 1 483 ? 41.789 76.682 0.041 1.00 11.10 ? 483 VAL A O 1 ATOM 3806 C CB . VAL A 1 483 ? 38.463 76.787 0.274 1.00 10.08 ? 483 VAL A CB 1 ATOM 3807 C CG1 . VAL A 1 483 ? 38.751 76.713 -1.207 1.00 12.34 ? 483 VAL A CG1 1 ATOM 3808 C CG2 . VAL A 1 483 ? 37.213 75.950 0.619 1.00 9.75 ? 483 VAL A CG2 1 ATOM 3809 N N . VAL A 1 484 ? 41.073 78.324 1.397 1.00 11.77 ? 484 VAL A N 1 ATOM 3810 C CA . VAL A 1 484 ? 42.246 79.160 1.152 1.00 11.62 ? 484 VAL A CA 1 ATOM 3811 C C . VAL A 1 484 ? 43.514 78.439 1.584 1.00 11.02 ? 484 VAL A C 1 ATOM 3812 O O . VAL A 1 484 ? 44.524 78.432 0.869 1.00 10.54 ? 484 VAL A O 1 ATOM 3813 C CB . VAL A 1 484 ? 42.119 80.514 1.857 1.00 12.92 ? 484 VAL A CB 1 ATOM 3814 C CG1 . VAL A 1 484 ? 43.497 81.285 1.775 1.00 14.82 ? 484 VAL A CG1 1 ATOM 3815 C CG2 . VAL A 1 484 ? 41.029 81.330 1.152 1.00 14.83 ? 484 VAL A CG2 1 ATOM 3816 N N . ASP A 1 485 ? 43.448 77.809 2.740 1.00 10.17 ? 485 ASP A N 1 ATOM 3817 C CA . ASP A 1 485 ? 44.629 77.039 3.181 1.00 12.02 ? 485 ASP A CA 1 ATOM 3818 C C . ASP A 1 485 ? 44.974 75.891 2.231 1.00 11.70 ? 485 ASP A C 1 ATOM 3819 O O . ASP A 1 485 ? 46.123 75.711 1.857 1.00 11.37 ? 485 ASP A O 1 ATOM 3820 C CB . ASP A 1 485 ? 44.384 76.484 4.561 1.00 11.71 ? 485 ASP A CB 1 ATOM 3821 C CG . ASP A 1 485 ? 45.649 75.855 5.156 1.00 12.89 ? 485 ASP A CG 1 ATOM 3822 O OD1 . ASP A 1 485 ? 46.663 76.603 5.236 1.00 16.64 ? 485 ASP A OD1 1 ATOM 3823 O OD2 . ASP A 1 485 ? 45.634 74.676 5.542 1.00 12.93 ? 485 ASP A OD2 1 ATOM 3824 N N . TYR A 1 486 ? 44.008 75.099 1.780 1.00 9.44 ? 486 TYR A N 1 ATOM 3825 C CA . TYR A 1 486 ? 44.328 74.028 0.832 1.00 10.32 ? 486 TYR A CA 1 ATOM 3826 C C . TYR A 1 486 ? 44.908 74.587 -0.471 1.00 10.00 ? 486 TYR A C 1 ATOM 3827 O O . TYR A 1 486 ? 45.824 74.019 -1.051 1.00 9.36 ? 486 TYR A O 1 ATOM 3828 C CB . TYR A 1 486 ? 43.077 73.251 0.440 1.00 11.92 ? 486 TYR A CB 1 ATOM 3829 C CG . TYR A 1 486 ? 42.465 72.475 1.587 1.00 9.79 ? 486 TYR A CG 1 ATOM 3830 C CD1 . TYR A 1 486 ? 43.254 71.609 2.334 1.00 12.08 ? 486 TYR A CD1 1 ATOM 3831 C CD2 . TYR A 1 486 ? 41.067 72.526 1.872 1.00 10.96 ? 486 TYR A CD2 1 ATOM 3832 C CE1 . TYR A 1 486 ? 42.719 70.798 3.298 1.00 12.34 ? 486 TYR A CE1 1 ATOM 3833 C CE2 . TYR A 1 486 ? 40.489 71.690 2.852 1.00 10.44 ? 486 TYR A CE2 1 ATOM 3834 C CZ . TYR A 1 486 ? 41.333 70.831 3.541 1.00 10.90 ? 486 TYR A CZ 1 ATOM 3835 O OH . TYR A 1 486 ? 40.685 69.974 4.420 1.00 9.20 ? 486 TYR A OH 1 ATOM 3836 N N . GLU A 1 487 ? 44.384 75.737 -0.902 1.00 11.21 ? 487 GLU A N 1 ATOM 3837 C CA . GLU A 1 487 ? 44.902 76.308 -2.156 1.00 9.89 ? 487 GLU A CA 1 ATOM 3838 C C . GLU A 1 487 ? 46.348 76.744 -1.998 1.00 11.18 ? 487 GLU A C 1 ATOM 3839 O O . GLU A 1 487 ? 47.186 76.515 -2.886 1.00 10.10 ? 487 GLU A O 1 ATOM 3840 C CB . GLU A 1 487 ? 44.037 77.509 -2.621 1.00 10.38 ? 487 GLU A CB 1 ATOM 3841 C CG . GLU A 1 487 ? 44.481 78.120 -3.946 1.00 13.05 ? 487 GLU A CG 1 ATOM 3842 C CD . GLU A 1 487 ? 43.613 79.301 -4.344 1.00 16.82 ? 487 GLU A CD 1 ATOM 3843 O OE1 . GLU A 1 487 ? 42.476 79.432 -3.848 1.00 16.12 ? 487 GLU A OE1 1 ATOM 3844 O OE2 . GLU A 1 487 ? 44.103 80.115 -5.184 1.00 21.64 ? 487 GLU A OE2 1 ATOM 3845 N N . GLN A 1 488 ? 46.618 77.405 -0.876 1.00 10.64 ? 488 GLN A N 1 ATOM 3846 C CA . GLN A 1 488 ? 48.010 77.883 -0.678 1.00 13.47 ? 488 GLN A CA 1 ATOM 3847 C C . GLN A 1 488 ? 48.955 76.723 -0.631 1.00 13.31 ? 488 GLN A C 1 ATOM 3848 O O . GLN A 1 488 ? 50.059 76.793 -1.146 1.00 11.20 ? 488 GLN A O 1 ATOM 3849 C CB . GLN A 1 488 ? 48.131 78.602 0.670 1.00 15.60 ? 488 GLN A CB 1 ATOM 3850 C CG . GLN A 1 488 ? 47.484 79.955 0.713 1.00 23.45 ? 488 GLN A CG 1 ATOM 3851 C CD . GLN A 1 488 ? 47.581 80.559 2.155 1.00 28.36 ? 488 GLN A CD 1 ATOM 3852 O OE1 . GLN A 1 488 ? 46.989 80.021 3.119 1.00 33.50 ? 488 GLN A OE1 1 ATOM 3853 N NE2 . GLN A 1 488 ? 48.333 81.651 2.300 1.00 32.04 ? 488 GLN A NE2 1 ATOM 3854 N N . ARG A 1 489 ? 48.548 75.629 0.029 1.00 12.76 ? 489 ARG A N 1 ATOM 3855 C CA . ARG A 1 489 ? 49.385 74.427 0.091 1.00 8.84 ? 489 ARG A CA 1 ATOM 3856 C C . ARG A 1 489 ? 49.594 73.860 -1.277 1.00 10.60 ? 489 ARG A C 1 ATOM 3857 O O . ARG A 1 489 ? 50.703 73.523 -1.621 1.00 10.64 ? 489 ARG A O 1 ATOM 3858 C CB . ARG A 1 489 ? 48.704 73.391 0.990 1.00 10.77 ? 489 ARG A CB 1 ATOM 3859 C CG . ARG A 1 489 ? 48.805 73.749 2.426 1.00 7.81 ? 489 ARG A CG 1 ATOM 3860 C CD . ARG A 1 489 ? 47.813 72.832 3.241 1.00 11.25 ? 489 ARG A CD 1 ATOM 3861 N NE . ARG A 1 489 ? 47.933 72.969 4.693 1.00 11.44 ? 489 ARG A NE 1 ATOM 3862 C CZ . ARG A 1 489 ? 48.780 72.288 5.480 1.00 16.16 ? 489 ARG A CZ 1 ATOM 3863 N NH1 . ARG A 1 489 ? 49.608 71.395 4.974 1.00 14.53 ? 489 ARG A NH1 1 ATOM 3864 N NH2 . ARG A 1 489 ? 48.746 72.470 6.813 1.00 14.22 ? 489 ARG A NH2 1 ATOM 3865 N N . MET A 1 490 ? 48.543 73.715 -2.070 1.00 9.45 ? 490 MET A N 1 ATOM 3866 C CA . MET A 1 490 ? 48.757 73.201 -3.382 1.00 9.83 ? 490 MET A CA 1 ATOM 3867 C C . MET A 1 490 ? 49.628 74.128 -4.219 1.00 8.95 ? 490 MET A C 1 ATOM 3868 O O . MET A 1 490 ? 50.328 73.634 -5.085 1.00 10.13 ? 490 MET A O 1 ATOM 3869 C CB . MET A 1 490 ? 47.449 72.938 -4.122 1.00 9.05 ? 490 MET A CB 1 ATOM 3870 C CG . MET A 1 490 ? 46.671 71.789 -3.399 1.00 13.45 ? 490 MET A CG 1 ATOM 3871 S SD . MET A 1 490 ? 45.328 71.049 -4.513 1.00 13.62 ? 490 MET A SD 1 ATOM 3872 C CE . MET A 1 490 ? 43.998 72.255 -4.366 1.00 14.40 ? 490 MET A CE 1 ATOM 3873 N N . GLN A 1 491 ? 49.494 75.449 -4.036 1.00 11.41 ? 491 GLN A N 1 ATOM 3874 C CA . GLN A 1 491 ? 50.364 76.358 -4.793 1.00 12.58 ? 491 GLN A CA 1 ATOM 3875 C C . GLN A 1 491 ? 51.827 76.044 -4.488 1.00 13.37 ? 491 GLN A C 1 ATOM 3876 O O . GLN A 1 491 ? 52.677 75.973 -5.381 1.00 12.50 ? 491 GLN A O 1 ATOM 3877 C CB . GLN A 1 491 ? 50.074 77.814 -4.429 1.00 16.14 ? 491 GLN A CB 1 ATOM 3878 C CG . GLN A 1 491 ? 50.847 78.781 -5.340 1.00 22.81 ? 491 GLN A CG 1 ATOM 3879 C CD . GLN A 1 491 ? 50.548 78.520 -6.823 1.00 26.27 ? 491 GLN A CD 1 ATOM 3880 O OE1 . GLN A 1 491 ? 49.387 78.610 -7.243 1.00 31.43 ? 491 GLN A OE1 1 ATOM 3881 N NE2 . GLN A 1 491 ? 51.578 78.177 -7.607 1.00 27.70 ? 491 GLN A NE2 1 ATOM 3882 N N . GLU A 1 492 ? 52.128 75.841 -3.222 1.00 11.80 ? 492 GLU A N 1 ATOM 3883 C CA . GLU A 1 492 ? 53.529 75.533 -2.910 1.00 12.75 ? 492 GLU A CA 1 ATOM 3884 C C . GLU A 1 492 ? 53.961 74.182 -3.498 1.00 12.62 ? 492 GLU A C 1 ATOM 3885 O O . GLU A 1 492 ? 55.088 73.973 -3.915 1.00 12.43 ? 492 GLU A O 1 ATOM 3886 C CB . GLU A 1 492 ? 53.662 75.512 -1.415 1.00 13.65 ? 492 GLU A CB 1 ATOM 3887 C CG . GLU A 1 492 ? 53.411 76.885 -0.761 1.00 19.88 ? 492 GLU A CG 1 ATOM 3888 C CD . GLU A 1 492 ? 54.437 77.965 -1.200 1.00 25.18 ? 492 GLU A CD 1 ATOM 3889 O OE1 . GLU A 1 492 ? 55.621 77.628 -1.478 1.00 27.13 ? 492 GLU A OE1 1 ATOM 3890 O OE2 . GLU A 1 492 ? 54.070 79.159 -1.266 1.00 28.49 ? 492 GLU A OE2 1 ATOM 3891 N N . ALA A 1 493 ? 53.020 73.240 -3.506 1.00 9.73 ? 493 ALA A N 1 ATOM 3892 C CA . ALA A 1 493 ? 53.307 71.950 -4.084 1.00 7.95 ? 493 ALA A CA 1 ATOM 3893 C C . ALA A 1 493 ? 53.659 72.086 -5.583 1.00 10.31 ? 493 ALA A C 1 ATOM 3894 O O . ALA A 1 493 ? 54.585 71.494 -6.043 1.00 9.41 ? 493 ALA A O 1 ATOM 3895 C CB . ALA A 1 493 ? 52.050 71.010 -3.846 1.00 9.23 ? 493 ALA A CB 1 ATOM 3896 N N . LEU A 1 494 ? 52.880 72.856 -6.349 1.00 8.85 ? 494 LEU A N 1 ATOM 3897 C CA . LEU A 1 494 ? 53.207 73.083 -7.742 1.00 10.23 ? 494 LEU A CA 1 ATOM 3898 C C . LEU A 1 494 ? 54.623 73.725 -7.837 1.00 9.68 ? 494 LEU A C 1 ATOM 3899 O O . LEU A 1 494 ? 55.384 73.340 -8.699 1.00 11.35 ? 494 LEU A O 1 ATOM 3900 C CB . LEU A 1 494 ? 52.151 74.010 -8.326 1.00 10.27 ? 494 LEU A CB 1 ATOM 3901 C CG . LEU A 1 494 ? 50.767 73.386 -8.459 1.00 10.94 ? 494 LEU A CG 1 ATOM 3902 C CD1 . LEU A 1 494 ? 49.723 74.484 -8.807 1.00 12.39 ? 494 LEU A CD1 1 ATOM 3903 C CD2 . LEU A 1 494 ? 50.799 72.381 -9.588 1.00 10.61 ? 494 LEU A CD2 1 ATOM 3904 N N . LYS A 1 495 ? 54.931 74.706 -7.008 1.00 12.49 ? 495 LYS A N 1 ATOM 3905 C CA . LYS A 1 495 ? 56.288 75.314 -7.080 1.00 12.50 ? 495 LYS A CA 1 ATOM 3906 C C . LYS A 1 495 ? 57.398 74.257 -6.807 1.00 13.60 ? 495 LYS A C 1 ATOM 3907 O O . LYS A 1 495 ? 58.466 74.212 -7.443 1.00 12.69 ? 495 LYS A O 1 ATOM 3908 C CB . LYS A 1 495 ? 56.418 76.444 -6.048 1.00 12.25 ? 495 LYS A CB 1 ATOM 3909 C CG . LYS A 1 495 ? 55.565 77.739 -6.205 1.00 16.16 ? 495 LYS A CG 1 ATOM 3910 C CD . LYS A 1 495 ? 56.066 78.867 -5.254 1.00 20.15 ? 495 LYS A CD 1 ATOM 3911 C CE . LYS A 1 495 ? 54.958 79.381 -4.346 1.00 24.22 ? 495 LYS A CE 1 ATOM 3912 N NZ . LYS A 1 495 ? 55.350 80.387 -3.288 1.00 24.40 ? 495 LYS A NZ 1 ATOM 3913 N N . ALA A 1 496 ? 57.107 73.339 -5.905 1.00 11.48 ? 496 ALA A N 1 ATOM 3914 C CA . ALA A 1 496 ? 58.092 72.316 -5.563 1.00 11.92 ? 496 ALA A CA 1 ATOM 3915 C C . ALA A 1 496 ? 58.245 71.379 -6.757 1.00 12.61 ? 496 ALA A C 1 ATOM 3916 O O . ALA A 1 496 ? 59.334 71.012 -7.145 1.00 10.49 ? 496 ALA A O 1 ATOM 3917 C CB . ALA A 1 496 ? 57.621 71.587 -4.256 1.00 12.49 ? 496 ALA A CB 1 ATOM 3918 N N . CYS A 1 497 ? 57.160 70.967 -7.401 1.00 9.33 ? 497 CYS A N 1 ATOM 3919 C CA . CYS A 1 497 ? 57.247 70.136 -8.575 1.00 11.54 ? 497 CYS A CA 1 ATOM 3920 C C . CYS A 1 497 ? 58.058 70.832 -9.699 1.00 9.73 ? 497 CYS A C 1 ATOM 3921 O O . CYS A 1 497 ? 58.875 70.216 -10.348 1.00 10.60 ? 497 CYS A O 1 ATOM 3922 C CB . CYS A 1 497 ? 55.805 69.838 -9.037 1.00 7.50 ? 497 CYS A CB 1 ATOM 3923 S SG . CYS A 1 497 ? 54.905 68.626 -7.985 1.00 10.95 ? 497 CYS A SG 1 ATOM 3924 N N . GLN A 1 498 ? 57.740 72.094 -9.945 1.00 10.51 ? 498 GLN A N 1 ATOM 3925 C CA . GLN A 1 498 ? 58.449 72.841 -10.991 1.00 11.63 ? 498 GLN A CA 1 ATOM 3926 C C . GLN A 1 498 ? 59.935 72.825 -10.756 1.00 11.59 ? 498 GLN A C 1 ATOM 3927 O O . GLN A 1 498 ? 60.690 72.542 -11.707 1.00 10.08 ? 498 GLN A O 1 ATOM 3928 C CB . GLN A 1 498 ? 57.938 74.288 -11.054 1.00 11.98 ? 498 GLN A CB 1 ATOM 3929 C CG . GLN A 1 498 ? 58.738 75.128 -12.099 1.00 17.68 ? 498 GLN A CG 1 ATOM 3930 C CD . GLN A 1 498 ? 58.199 76.554 -12.250 1.00 21.08 ? 498 GLN A CD 1 ATOM 3931 O OE1 . GLN A 1 498 ? 57.922 77.013 -13.361 1.00 21.67 ? 498 GLN A OE1 1 ATOM 3932 N NE2 . GLN A 1 498 ? 58.071 77.260 -11.129 1.00 23.00 ? 498 GLN A NE2 1 ATOM 3933 N N . MET A 1 499 ? 60.323 73.061 -9.530 1.00 10.87 ? 499 MET A N 1 ATOM 3934 C CA . MET A 1 499 ? 61.763 73.055 -9.197 1.00 11.25 ? 499 MET A CA 1 ATOM 3935 C C . MET A 1 499 ? 62.395 71.715 -9.504 1.00 13.26 ? 499 MET A C 1 ATOM 3936 O O . MET A 1 499 ? 63.406 71.657 -10.190 1.00 12.58 ? 499 MET A O 1 ATOM 3937 C CB . MET A 1 499 ? 61.940 73.395 -7.741 1.00 10.63 ? 499 MET A CB 1 ATOM 3938 C CG . MET A 1 499 ? 63.368 73.215 -7.176 1.00 14.43 ? 499 MET A CG 1 ATOM 3939 S SD . MET A 1 499 ? 64.653 74.138 -8.090 1.00 22.31 ? 499 MET A SD 1 ATOM 3940 C CE . MET A 1 499 ? 64.066 75.690 -7.747 1.00 17.55 ? 499 MET A CE 1 ATOM 3941 N N . VAL A 1 500 ? 61.791 70.611 -9.025 1.00 11.55 ? 500 VAL A N 1 ATOM 3942 C CA . VAL A 1 500 ? 62.337 69.302 -9.322 1.00 10.18 ? 500 VAL A CA 1 ATOM 3943 C C . VAL A 1 500 ? 62.357 69.002 -10.798 1.00 12.09 ? 500 VAL A C 1 ATOM 3944 O O . VAL A 1 500 ? 63.348 68.549 -11.331 1.00 10.87 ? 500 VAL A O 1 ATOM 3945 C CB . VAL A 1 500 ? 61.529 68.189 -8.534 1.00 11.66 ? 500 VAL A CB 1 ATOM 3946 C CG1 . VAL A 1 500 ? 62.032 66.803 -8.922 1.00 10.61 ? 500 VAL A CG1 1 ATOM 3947 C CG2 . VAL A 1 500 ? 61.606 68.448 -7.048 1.00 11.89 ? 500 VAL A CG2 1 ATOM 3948 N N . MET A 1 501 ? 61.252 69.263 -11.500 1.00 10.97 ? 501 MET A N 1 ATOM 3949 C CA . MET A 1 501 ? 61.192 68.998 -12.958 1.00 12.61 ? 501 MET A CA 1 ATOM 3950 C C . MET A 1 501 ? 62.284 69.757 -13.707 1.00 12.22 ? 501 MET A C 1 ATOM 3951 O O . MET A 1 501 ? 62.963 69.177 -14.522 1.00 11.47 ? 501 MET A O 1 ATOM 3952 C CB . MET A 1 501 ? 59.827 69.412 -13.557 1.00 11.22 ? 501 MET A CB 1 ATOM 3953 C CG . MET A 1 501 ? 58.714 68.562 -12.950 1.00 11.32 ? 501 MET A CG 1 ATOM 3954 S SD . MET A 1 501 ? 57.039 69.116 -13.306 1.00 14.04 ? 501 MET A SD 1 ATOM 3955 C CE . MET A 1 501 ? 56.906 68.774 -14.984 1.00 15.44 ? 501 MET A CE 1 ATOM 3956 N N . GLN A 1 502 ? 62.425 71.043 -13.423 1.00 13.95 ? 502 GLN A N 1 ATOM 3957 C CA . GLN A 1 502 ? 63.387 71.843 -14.209 1.00 14.35 ? 502 GLN A CA 1 ATOM 3958 C C . GLN A 1 502 ? 64.843 71.463 -13.897 1.00 14.38 ? 502 GLN A C 1 ATOM 3959 O O . GLN A 1 502 ? 65.668 71.359 -14.825 1.00 11.34 ? 502 GLN A O 1 ATOM 3960 C CB . GLN A 1 502 ? 63.106 73.335 -14.029 1.00 15.21 ? 502 GLN A CB 1 ATOM 3961 C CG . GLN A 1 502 ? 63.318 73.955 -12.669 1.00 15.57 ? 502 GLN A CG 1 ATOM 3962 C CD . GLN A 1 502 ? 64.751 74.404 -12.465 1.00 18.02 ? 502 GLN A CD 1 ATOM 3963 O OE1 . GLN A 1 502 ? 65.537 74.489 -13.472 1.00 16.30 ? 502 GLN A OE1 1 ATOM 3964 N NE2 . GLN A 1 502 ? 65.116 74.706 -11.216 1.00 17.40 ? 502 GLN A NE2 1 ATOM 3965 N N . GLN A 1 503 ? 65.145 71.168 -12.641 1.00 12.89 ? 503 GLN A N 1 ATOM 3966 C CA . GLN A 1 503 ? 66.515 70.666 -12.322 1.00 13.13 ? 503 GLN A CA 1 ATOM 3967 C C . GLN A 1 503 ? 66.754 69.335 -13.060 1.00 13.29 ? 503 GLN A C 1 ATOM 3968 O O . GLN A 1 503 ? 67.855 69.085 -13.521 1.00 13.72 ? 503 GLN A O 1 ATOM 3969 C CB . GLN A 1 503 ? 66.688 70.416 -10.799 1.00 13.93 ? 503 GLN A CB 1 ATOM 3970 C CG . GLN A 1 503 ? 66.835 71.668 -9.916 1.00 14.77 ? 503 GLN A CG 1 ATOM 3971 C CD . GLN A 1 503 ? 68.187 72.412 -10.091 1.00 14.72 ? 503 GLN A CD 1 ATOM 3972 O OE1 . GLN A 1 503 ? 69.174 71.781 -10.458 1.00 16.88 ? 503 GLN A OE1 1 ATOM 3973 N NE2 . GLN A 1 503 ? 68.221 73.730 -9.794 1.00 17.86 ? 503 GLN A NE2 1 ATOM 3974 N N . SER A 1 504 ? 65.743 68.442 -13.159 1.00 11.16 ? 504 SER A N 1 ATOM 3975 C CA . SER A 1 504 ? 65.877 67.152 -13.833 1.00 12.79 ? 504 SER A CA 1 ATOM 3976 C C . SER A 1 504 ? 66.108 67.257 -15.364 1.00 12.77 ? 504 SER A C 1 ATOM 3977 O O . SER A 1 504 ? 66.913 66.511 -15.970 1.00 11.15 ? 504 SER A O 1 ATOM 3978 C CB . SER A 1 504 ? 64.655 66.247 -13.585 1.00 13.44 ? 504 SER A CB 1 ATOM 3979 O OG . SER A 1 504 ? 64.398 66.014 -12.204 1.00 11.07 ? 504 SER A OG 1 ATOM 3980 N N . VAL A 1 505 ? 65.338 68.154 -15.999 1.00 13.18 ? 505 VAL A N 1 ATOM 3981 C CA . VAL A 1 505 ? 65.495 68.392 -17.455 1.00 12.28 ? 505 VAL A CA 1 ATOM 3982 C C . VAL A 1 505 ? 66.941 68.876 -17.736 1.00 11.86 ? 505 VAL A C 1 ATOM 3983 O O . VAL A 1 505 ? 67.595 68.412 -18.681 1.00 12.72 ? 505 VAL A O 1 ATOM 3984 C CB . VAL A 1 505 ? 64.470 69.434 -17.946 1.00 13.37 ? 505 VAL A CB 1 ATOM 3985 C CG1 . VAL A 1 505 ? 64.737 69.795 -19.459 1.00 14.31 ? 505 VAL A CG1 1 ATOM 3986 C CG2 . VAL A 1 505 ? 63.040 68.828 -17.860 1.00 13.52 ? 505 VAL A CG2 1 ATOM 3987 N N . TYR A 1 506 ? 67.404 69.818 -16.961 1.00 13.92 ? 506 TYR A N 1 ATOM 3988 C CA . TYR A 1 506 ? 68.779 70.309 -17.184 1.00 15.32 ? 506 TYR A CA 1 ATOM 3989 C C . TYR A 1 506 ? 69.813 69.203 -17.041 1.00 16.61 ? 506 TYR A C 1 ATOM 3990 O O . TYR A 1 506 ? 70.762 69.121 -17.802 1.00 16.08 ? 506 TYR A O 1 ATOM 3991 C CB . TYR A 1 506 ? 69.087 71.426 -16.217 1.00 15.66 ? 506 TYR A CB 1 ATOM 3992 C CG . TYR A 1 506 ? 70.493 71.974 -16.310 1.00 19.14 ? 506 TYR A CG 1 ATOM 3993 C CD1 . TYR A 1 506 ? 71.009 72.528 -17.511 1.00 21.90 ? 506 TYR A CD1 1 ATOM 3994 C CD2 . TYR A 1 506 ? 71.328 71.893 -15.220 1.00 20.78 ? 506 TYR A CD2 1 ATOM 3995 C CE1 . TYR A 1 506 ? 72.360 72.966 -17.575 1.00 21.37 ? 506 TYR A CE1 1 ATOM 3996 C CE2 . TYR A 1 506 ? 72.656 72.321 -15.277 1.00 23.51 ? 506 TYR A CE2 1 ATOM 3997 C CZ . TYR A 1 506 ? 73.175 72.838 -16.428 1.00 23.42 ? 506 TYR A CZ 1 ATOM 3998 O OH . TYR A 1 506 ? 74.549 73.162 -16.368 1.00 24.25 ? 506 TYR A OH 1 ATOM 3999 N N . ARG A 1 507 ? 69.643 68.323 -16.073 1.00 14.66 ? 507 ARG A N 1 ATOM 4000 C CA . ARG A 1 507 ? 70.590 67.217 -15.912 1.00 12.77 ? 507 ARG A CA 1 ATOM 4001 C C . ARG A 1 507 ? 70.398 66.150 -17.027 1.00 14.46 ? 507 ARG A C 1 ATOM 4002 O O . ARG A 1 507 ? 71.356 65.565 -17.534 1.00 13.75 ? 507 ARG A O 1 ATOM 4003 C CB . ARG A 1 507 ? 70.362 66.591 -14.517 1.00 12.15 ? 507 ARG A CB 1 ATOM 4004 C CG . ARG A 1 507 ? 71.407 65.526 -14.153 1.00 15.16 ? 507 ARG A CG 1 ATOM 4005 C CD . ARG A 1 507 ? 71.189 65.033 -12.727 1.00 14.88 ? 507 ARG A CD 1 ATOM 4006 N NE . ARG A 1 507 ? 72.218 64.048 -12.374 1.00 18.93 ? 507 ARG A NE 1 ATOM 4007 C CZ . ARG A 1 507 ? 72.300 63.428 -11.191 1.00 17.27 ? 507 ARG A CZ 1 ATOM 4008 N NH1 . ARG A 1 507 ? 71.432 63.683 -10.226 1.00 20.32 ? 507 ARG A NH1 1 ATOM 4009 N NH2 . ARG A 1 507 ? 73.219 62.483 -11.020 1.00 19.75 ? 507 ARG A NH2 1 ATOM 4010 N N . LEU A 1 508 ? 69.151 65.900 -17.450 1.00 10.98 ? 508 LEU A N 1 ATOM 4011 C CA . LEU A 1 508 ? 68.907 64.894 -18.455 1.00 12.12 ? 508 LEU A CA 1 ATOM 4012 C C . LEU A 1 508 ? 69.351 65.310 -19.859 1.00 11.22 ? 508 LEU A C 1 ATOM 4013 O O . LEU A 1 508 ? 69.625 64.462 -20.714 1.00 13.58 ? 508 LEU A O 1 ATOM 4014 C CB . LEU A 1 508 ? 67.427 64.503 -18.436 1.00 11.48 ? 508 LEU A CB 1 ATOM 4015 C CG . LEU A 1 508 ? 66.958 63.635 -17.213 1.00 10.84 ? 508 LEU A CG 1 ATOM 4016 C CD1 . LEU A 1 508 ? 65.398 63.684 -17.134 1.00 7.39 ? 508 LEU A CD1 1 ATOM 4017 C CD2 . LEU A 1 508 ? 67.376 62.160 -17.387 1.00 11.91 ? 508 LEU A CD2 1 ATOM 4018 N N . LEU A 1 509 ? 69.418 66.641 -20.091 1.00 13.32 ? 509 LEU A N 1 ATOM 4019 C CA . LEU A 1 509 ? 69.775 67.132 -21.429 1.00 14.72 ? 509 LEU A CA 1 ATOM 4020 C C . LEU A 1 509 ? 71.030 67.967 -21.507 1.00 16.16 ? 509 LEU A C 1 ATOM 4021 O O . LEU A 1 509 ? 71.185 68.777 -22.433 1.00 15.11 ? 509 LEU A O 1 ATOM 4022 C CB . LEU A 1 509 ? 68.587 67.916 -22.048 1.00 13.06 ? 509 LEU A CB 1 ATOM 4023 C CG . LEU A 1 509 ? 67.357 67.047 -22.376 1.00 12.39 ? 509 LEU A CG 1 ATOM 4024 C CD1 . LEU A 1 509 ? 66.185 68.008 -22.736 1.00 10.63 ? 509 LEU A CD1 1 ATOM 4025 C CD2 . LEU A 1 509 ? 67.573 66.065 -23.527 1.00 12.95 ? 509 LEU A CD2 1 ATOM 4026 N N . THR A 1 510 ? 71.938 67.802 -20.560 1.00 14.14 ? 510 THR A N 1 ATOM 4027 C CA . THR A 1 510 ? 73.192 68.579 -20.639 1.00 14.09 ? 510 THR A CA 1 ATOM 4028 C C . THR A 1 510 ? 74.349 67.594 -20.649 1.00 15.96 ? 510 THR A C 1 ATOM 4029 O O . THR A 1 510 ? 74.345 66.609 -19.884 1.00 15.66 ? 510 THR A O 1 ATOM 4030 C CB . THR A 1 510 ? 73.357 69.544 -19.483 1.00 13.33 ? 510 THR A CB 1 ATOM 4031 O OG1 . THR A 1 510 ? 72.243 70.489 -19.450 1.00 15.45 ? 510 THR A OG1 1 ATOM 4032 C CG2 . THR A 1 510 ? 74.680 70.350 -19.649 1.00 14.58 ? 510 THR A CG2 1 ATOM 4033 N N . LYS A 1 511 ? 75.330 67.840 -21.524 1.00 15.23 ? 511 LYS A N 1 ATOM 4034 C CA . LYS A 1 511 ? 76.500 66.963 -21.667 1.00 17.17 ? 511 LYS A CA 1 ATOM 4035 C C . LYS A 1 511 ? 77.027 66.730 -20.258 1.00 15.44 ? 511 LYS A C 1 ATOM 4036 O O . LYS A 1 511 ? 77.326 67.699 -19.569 1.00 16.64 ? 511 LYS A O 1 ATOM 4037 C CB . LYS A 1 511 ? 77.561 67.663 -22.520 1.00 18.35 ? 511 LYS A CB 1 ATOM 4038 C CG . LYS A 1 511 ? 78.747 66.776 -22.765 1.00 23.92 ? 511 LYS A CG 1 ATOM 4039 C CD . LYS A 1 511 ? 79.807 67.395 -23.642 1.00 26.16 ? 511 LYS A CD 1 ATOM 4040 C CE . LYS A 1 511 ? 80.920 66.367 -23.825 1.00 29.38 ? 511 LYS A CE 1 ATOM 4041 N NZ . LYS A 1 511 ? 82.230 66.937 -24.201 1.00 31.01 ? 511 LYS A NZ 1 ATOM 4042 N N . PRO A 1 512 ? 77.196 65.434 -19.820 1.00 16.28 ? 512 PRO A N 1 ATOM 4043 C CA . PRO A 1 512 ? 77.683 65.204 -18.446 1.00 16.57 ? 512 PRO A CA 1 ATOM 4044 C C . PRO A 1 512 ? 78.920 65.947 -17.972 1.00 15.45 ? 512 PRO A C 1 ATOM 4045 O O . PRO A 1 512 ? 78.938 66.402 -16.832 1.00 17.81 ? 512 PRO A O 1 ATOM 4046 C CB . PRO A 1 512 ? 77.884 63.687 -18.386 1.00 16.84 ? 512 PRO A CB 1 ATOM 4047 C CG . PRO A 1 512 ? 76.828 63.192 -19.278 1.00 17.42 ? 512 PRO A CG 1 ATOM 4048 C CD . PRO A 1 512 ? 76.964 64.149 -20.490 1.00 16.76 ? 512 PRO A CD 1 ATOM 4049 N N . SER A 1 513 ? 79.920 66.111 -18.837 1.00 17.09 ? 513 SER A N 1 ATOM 4050 C CA . SER A 1 513 ? 81.154 66.819 -18.477 1.00 17.60 ? 513 SER A CA 1 ATOM 4051 C C . SER A 1 513 ? 81.016 68.323 -18.394 1.00 18.10 ? 513 SER A C 1 ATOM 4052 O O . SER A 1 513 ? 81.940 69.006 -17.943 1.00 19.01 ? 513 SER A O 1 ATOM 4053 C CB . SER A 1 513 ? 82.294 66.468 -19.446 1.00 16.66 ? 513 SER A CB 1 ATOM 4054 O OG . SER A 1 513 ? 81.919 66.586 -20.788 1.00 20.35 ? 513 SER A OG 1 ATOM 4055 N N . ILE A 1 514 ? 79.864 68.844 -18.832 1.00 18.36 ? 514 ILE A N 1 ATOM 4056 C CA . ILE A 1 514 ? 79.572 70.277 -18.778 1.00 18.98 ? 514 ILE A CA 1 ATOM 4057 C C . ILE A 1 514 ? 78.564 70.552 -17.662 1.00 17.14 ? 514 ILE A C 1 ATOM 4058 O O . ILE A 1 514 ? 78.592 71.582 -17.041 1.00 17.23 ? 514 ILE A O 1 ATOM 4059 C CB . ILE A 1 514 ? 79.008 70.763 -20.140 1.00 22.08 ? 514 ILE A CB 1 ATOM 4060 C CG1 . ILE A 1 514 ? 80.115 70.723 -21.205 1.00 23.57 ? 514 ILE A CG1 1 ATOM 4061 C CG2 . ILE A 1 514 ? 78.476 72.191 -19.999 1.00 20.84 ? 514 ILE A CG2 1 ATOM 4062 C CD1 . ILE A 1 514 ? 79.618 70.742 -22.631 1.00 27.12 ? 514 ILE A CD1 1 ATOM 4063 N N . TYR A 1 515 ? 77.706 69.575 -17.360 1.00 16.44 ? 515 TYR A N 1 ATOM 4064 C CA . TYR A 1 515 ? 76.675 69.777 -16.304 1.00 14.48 ? 515 TYR A CA 1 ATOM 4065 C C . TYR A 1 515 ? 77.235 70.416 -15.021 1.00 14.90 ? 515 TYR A C 1 ATOM 4066 O O . TYR A 1 515 ? 78.113 69.814 -14.389 1.00 15.52 ? 515 TYR A O 1 ATOM 4067 C CB . TYR A 1 515 ? 76.043 68.411 -15.992 1.00 15.90 ? 515 TYR A CB 1 ATOM 4068 C CG . TYR A 1 515 ? 75.005 68.422 -14.914 1.00 16.60 ? 515 TYR A CG 1 ATOM 4069 C CD1 . TYR A 1 515 ? 73.801 69.087 -15.077 1.00 14.51 ? 515 TYR A CD1 1 ATOM 4070 C CD2 . TYR A 1 515 ? 75.230 67.737 -13.723 1.00 15.76 ? 515 TYR A CD2 1 ATOM 4071 C CE1 . TYR A 1 515 ? 72.828 69.068 -14.046 1.00 17.68 ? 515 TYR A CE1 1 ATOM 4072 C CE2 . TYR A 1 515 ? 74.279 67.696 -12.715 1.00 17.56 ? 515 TYR A CE2 1 ATOM 4073 C CZ . TYR A 1 515 ? 73.088 68.359 -12.891 1.00 17.09 ? 515 TYR A CZ 1 ATOM 4074 O OH . TYR A 1 515 ? 72.153 68.258 -11.930 1.00 17.42 ? 515 TYR A OH 1 ATOM 4075 N N . SER A 1 516 ? 76.776 71.598 -14.608 1.00 16.36 ? 516 SER A N 1 ATOM 4076 C CA . SER A 1 516 ? 77.302 72.255 -13.395 1.00 16.46 ? 516 SER A CA 1 ATOM 4077 C C . SER A 1 516 ? 76.134 72.929 -12.724 1.00 18.35 ? 516 SER A C 1 ATOM 4078 O O . SER A 1 516 ? 75.940 74.132 -12.903 1.00 19.30 ? 516 SER A O 1 ATOM 4079 C CB . SER A 1 516 ? 78.349 73.352 -13.740 1.00 16.70 ? 516 SER A CB 1 ATOM 4080 O OG . SER A 1 516 ? 78.898 73.948 -12.546 1.00 20.97 ? 516 SER A OG 1 ATOM 4081 N N . PRO A 1 517 ? 75.376 72.178 -11.908 1.00 16.78 ? 517 PRO A N 1 ATOM 4082 C CA . PRO A 1 517 ? 74.204 72.731 -11.240 1.00 19.04 ? 517 PRO A CA 1 ATOM 4083 C C . PRO A 1 517 ? 74.357 73.503 -9.971 1.00 19.81 ? 517 PRO A C 1 ATOM 4084 O O . PRO A 1 517 ? 75.256 73.237 -9.179 1.00 22.47 ? 517 PRO A O 1 ATOM 4085 C CB . PRO A 1 517 ? 73.318 71.500 -11.018 1.00 17.78 ? 517 PRO A CB 1 ATOM 4086 C CG . PRO A 1 517 ? 74.359 70.407 -10.720 1.00 16.33 ? 517 PRO A CG 1 ATOM 4087 C CD . PRO A 1 517 ? 75.483 70.729 -11.692 1.00 16.94 ? 517 PRO A CD 1 ATOM 4088 N N . ASP A 1 518 ? 73.482 74.494 -9.830 1.00 20.72 ? 518 ASP A N 1 ATOM 4089 C CA . ASP A 1 518 ? 73.295 75.284 -8.636 1.00 20.84 ? 518 ASP A CA 1 ATOM 4090 C C . ASP A 1 518 ? 71.852 74.858 -8.318 1.00 21.57 ? 518 ASP A C 1 ATOM 4091 O O . ASP A 1 518 ? 70.920 75.273 -8.990 1.00 20.41 ? 518 ASP A O 1 ATOM 4092 C CB . ASP A 1 518 ? 73.297 76.785 -8.915 1.00 22.62 ? 518 ASP A CB 1 ATOM 4093 C CG . ASP A 1 518 ? 72.899 77.578 -7.700 1.00 23.62 ? 518 ASP A CG 1 ATOM 4094 O OD1 . ASP A 1 518 ? 72.086 77.095 -6.882 1.00 26.02 ? 518 ASP A OD1 1 ATOM 4095 O OD2 . ASP A 1 518 ? 73.360 78.711 -7.556 1.00 27.69 ? 518 ASP A OD2 1 ATOM 4096 N N . PHE A 1 519 ? 71.686 74.004 -7.318 1.00 22.12 ? 519 PHE A N 1 ATOM 4097 C CA . PHE A 1 519 ? 70.367 73.487 -6.975 1.00 22.51 ? 519 PHE A CA 1 ATOM 4098 C C . PHE A 1 519 ? 69.288 74.483 -6.587 1.00 24.20 ? 519 PHE A C 1 ATOM 4099 O O . PHE A 1 519 ? 68.127 74.115 -6.388 1.00 23.31 ? 519 PHE A O 1 ATOM 4100 C CB . PHE A 1 519 ? 70.540 72.416 -5.889 1.00 21.45 ? 519 PHE A CB 1 ATOM 4101 C CG . PHE A 1 519 ? 71.375 71.281 -6.344 1.00 19.85 ? 519 PHE A CG 1 ATOM 4102 C CD1 . PHE A 1 519 ? 71.118 70.687 -7.554 1.00 19.74 ? 519 PHE A CD1 1 ATOM 4103 C CD2 . PHE A 1 519 ? 72.434 70.818 -5.589 1.00 20.02 ? 519 PHE A CD2 1 ATOM 4104 C CE1 . PHE A 1 519 ? 71.878 69.653 -8.037 1.00 18.89 ? 519 PHE A CE1 1 ATOM 4105 C CE2 . PHE A 1 519 ? 73.211 69.763 -6.068 1.00 19.19 ? 519 PHE A CE2 1 ATOM 4106 C CZ . PHE A 1 519 ? 72.935 69.197 -7.273 1.00 20.47 ? 519 PHE A CZ 1 ATOM 4107 N N . SER A 1 520 ? 69.640 75.753 -6.479 1.00 24.95 ? 520 SER A N 1 ATOM 4108 C CA . SER A 1 520 ? 68.658 76.764 -6.122 1.00 27.02 ? 520 SER A CA 1 ATOM 4109 C C . SER A 1 520 ? 68.343 77.643 -7.332 1.00 27.25 ? 520 SER A C 1 ATOM 4110 O O . SER A 1 520 ? 67.500 78.528 -7.260 1.00 28.93 ? 520 SER A O 1 ATOM 4111 C CB . SER A 1 520 ? 69.228 77.658 -5.060 1.00 28.34 ? 520 SER A CB 1 ATOM 4112 O OG . SER A 1 520 ? 70.331 78.367 -5.621 1.00 29.65 ? 520 SER A OG 1 ATOM 4113 N N . PHE A 1 521 ? 69.014 77.394 -8.436 1.00 26.87 ? 521 PHE A N 1 ATOM 4114 C CA . PHE A 1 521 ? 68.810 78.250 -9.599 1.00 26.41 ? 521 PHE A CA 1 ATOM 4115 C C . PHE A 1 521 ? 67.718 77.735 -10.535 1.00 24.82 ? 521 PHE A C 1 ATOM 4116 O O . PHE A 1 521 ? 67.464 76.536 -10.604 1.00 24.69 ? 521 PHE A O 1 ATOM 4117 C CB . PHE A 1 521 ? 70.138 78.376 -10.360 1.00 26.82 ? 521 PHE A CB 1 ATOM 4118 C CG . PHE A 1 521 ? 70.146 79.457 -11.372 1.00 28.50 ? 521 PHE A CG 1 ATOM 4119 C CD1 . PHE A 1 521 ? 70.278 80.785 -10.974 1.00 29.52 ? 521 PHE A CD1 1 ATOM 4120 C CD2 . PHE A 1 521 ? 69.971 79.164 -12.719 1.00 29.97 ? 521 PHE A CD2 1 ATOM 4121 C CE1 . PHE A 1 521 ? 70.227 81.810 -11.905 1.00 31.67 ? 521 PHE A CE1 1 ATOM 4122 C CE2 . PHE A 1 521 ? 69.918 80.196 -13.673 1.00 31.26 ? 521 PHE A CE2 1 ATOM 4123 C CZ . PHE A 1 521 ? 70.045 81.516 -13.252 1.00 30.28 ? 521 PHE A CZ 1 ATOM 4124 N N . SER A 1 522 ? 67.076 78.647 -11.257 1.00 24.12 ? 522 SER A N 1 ATOM 4125 C CA . SER A 1 522 ? 66.052 78.234 -12.204 1.00 22.32 ? 522 SER A CA 1 ATOM 4126 C C . SER A 1 522 ? 66.551 78.183 -13.649 1.00 20.09 ? 522 SER A C 1 ATOM 4127 O O . SER A 1 522 ? 66.609 79.225 -14.311 1.00 21.04 ? 522 SER A O 1 ATOM 4128 C CB . SER A 1 522 ? 64.838 79.153 -12.089 1.00 24.59 ? 522 SER A CB 1 ATOM 4129 O OG . SER A 1 522 ? 64.030 78.709 -10.992 1.00 30.76 ? 522 SER A OG 1 ATOM 4130 N N . TYR A 1 523 ? 66.929 76.991 -14.115 1.00 15.79 ? 523 TYR A N 1 ATOM 4131 C CA . TYR A 1 523 ? 67.397 76.773 -15.473 1.00 15.82 ? 523 TYR A CA 1 ATOM 4132 C C . TYR A 1 523 ? 66.271 76.839 -16.474 1.00 16.36 ? 523 TYR A C 1 ATOM 4133 O O . TYR A 1 523 ? 66.494 77.240 -17.610 1.00 15.43 ? 523 TYR A O 1 ATOM 4134 C CB . TYR A 1 523 ? 68.094 75.433 -15.640 1.00 16.15 ? 523 TYR A CB 1 ATOM 4135 C CG . TYR A 1 523 ? 69.358 75.412 -14.849 1.00 19.13 ? 523 TYR A CG 1 ATOM 4136 C CD1 . TYR A 1 523 ? 70.538 76.006 -15.340 1.00 15.32 ? 523 TYR A CD1 1 ATOM 4137 C CD2 . TYR A 1 523 ? 69.366 74.915 -13.535 1.00 15.88 ? 523 TYR A CD2 1 ATOM 4138 C CE1 . TYR A 1 523 ? 71.683 76.104 -14.509 1.00 18.72 ? 523 TYR A CE1 1 ATOM 4139 C CE2 . TYR A 1 523 ? 70.482 75.001 -12.751 1.00 19.58 ? 523 TYR A CE2 1 ATOM 4140 C CZ . TYR A 1 523 ? 71.640 75.601 -13.234 1.00 17.11 ? 523 TYR A CZ 1 ATOM 4141 O OH . TYR A 1 523 ? 72.746 75.707 -12.387 1.00 18.94 ? 523 TYR A OH 1 ATOM 4142 N N . PHE A 1 524 ? 65.078 76.395 -16.089 1.00 15.23 ? 524 PHE A N 1 ATOM 4143 C CA . PHE A 1 524 ? 63.912 76.451 -16.961 1.00 15.44 ? 524 PHE A CA 1 ATOM 4144 C C . PHE A 1 524 ? 62.722 76.948 -16.154 1.00 17.03 ? 524 PHE A C 1 ATOM 4145 O O . PHE A 1 524 ? 62.685 76.730 -14.942 1.00 15.37 ? 524 PHE A O 1 ATOM 4146 C CB . PHE A 1 524 ? 63.522 75.056 -17.477 1.00 14.59 ? 524 PHE A CB 1 ATOM 4147 C CG . PHE A 1 524 ? 64.543 74.407 -18.356 1.00 13.71 ? 524 PHE A CG 1 ATOM 4148 C CD1 . PHE A 1 524 ? 65.574 73.641 -17.820 1.00 15.28 ? 524 PHE A CD1 1 ATOM 4149 C CD2 . PHE A 1 524 ? 64.495 74.564 -19.744 1.00 15.02 ? 524 PHE A CD2 1 ATOM 4150 C CE1 . PHE A 1 524 ? 66.555 73.048 -18.688 1.00 14.79 ? 524 PHE A CE1 1 ATOM 4151 C CE2 . PHE A 1 524 ? 65.438 73.996 -20.610 1.00 13.02 ? 524 PHE A CE2 1 ATOM 4152 C CZ . PHE A 1 524 ? 66.481 73.233 -20.073 1.00 14.76 ? 524 PHE A CZ 1 ATOM 4153 N N . THR A 1 525 ? 61.754 77.603 -16.814 1.00 16.09 ? 525 THR A N 1 ATOM 4154 C CA . THR A 1 525 ? 60.501 77.959 -16.155 1.00 18.97 ? 525 THR A CA 1 ATOM 4155 C C . THR A 1 525 ? 59.436 77.139 -16.897 1.00 16.48 ? 525 THR A C 1 ATOM 4156 O O . THR A 1 525 ? 59.513 76.887 -18.115 1.00 17.35 ? 525 THR A O 1 ATOM 4157 C CB . THR A 1 525 ? 60.152 79.413 -16.279 1.00 20.95 ? 525 THR A CB 1 ATOM 4158 O OG1 . THR A 1 525 ? 59.857 79.673 -17.641 1.00 25.78 ? 525 THR A OG1 1 ATOM 4159 C CG2 . THR A 1 525 ? 61.307 80.287 -15.798 1.00 22.19 ? 525 THR A CG2 1 ATOM 4160 N N . LEU A 1 526 ? 58.435 76.663 -16.163 1.00 16.47 ? 526 LEU A N 1 ATOM 4161 C CA . LEU A 1 526 ? 57.398 75.856 -16.838 1.00 15.74 ? 526 LEU A CA 1 ATOM 4162 C C . LEU A 1 526 ? 56.373 76.812 -17.453 1.00 15.85 ? 526 LEU A C 1 ATOM 4163 O O . LEU A 1 526 ? 56.111 77.870 -16.901 1.00 18.68 ? 526 LEU A O 1 ATOM 4164 C CB . LEU A 1 526 ? 56.643 74.958 -15.845 1.00 17.13 ? 526 LEU A CB 1 ATOM 4165 C CG . LEU A 1 526 ? 57.074 73.521 -15.531 1.00 18.95 ? 526 LEU A CG 1 ATOM 4166 C CD1 . LEU A 1 526 ? 56.121 73.066 -14.430 1.00 19.58 ? 526 LEU A CD1 1 ATOM 4167 C CD2 . LEU A 1 526 ? 56.975 72.560 -16.676 1.00 19.88 ? 526 LEU A CD2 1 ATOM 4168 N N . ASP A 1 527 ? 55.835 76.428 -18.605 1.00 14.33 ? 527 ASP A N 1 ATOM 4169 C CA . ASP A 1 527 ? 54.821 77.234 -19.295 1.00 14.01 ? 527 ASP A CA 1 ATOM 4170 C C . ASP A 1 527 ? 53.577 76.328 -19.381 1.00 13.38 ? 527 ASP A C 1 ATOM 4171 O O . ASP A 1 527 ? 53.660 75.246 -19.866 1.00 15.38 ? 527 ASP A O 1 ATOM 4172 C CB . ASP A 1 527 ? 55.298 77.587 -20.715 1.00 15.49 ? 527 ASP A CB 1 ATOM 4173 C CG . ASP A 1 527 ? 54.246 78.403 -21.488 1.00 16.00 ? 527 ASP A CG 1 ATOM 4174 O OD1 . ASP A 1 527 ? 53.943 79.538 -21.051 1.00 18.42 ? 527 ASP A OD1 1 ATOM 4175 O OD2 . ASP A 1 527 ? 53.711 77.862 -22.476 1.00 18.86 ? 527 ASP A OD2 1 ATOM 4176 N N . ASP A 1 528 ? 52.448 76.764 -18.849 1.00 14.24 ? 528 ASP A N 1 ATOM 4177 C CA . ASP A 1 528 ? 51.268 75.914 -18.858 1.00 13.19 ? 528 ASP A CA 1 ATOM 4178 C C . ASP A 1 528 ? 50.135 76.746 -19.459 1.00 10.30 ? 528 ASP A C 1 ATOM 4179 O O . ASP A 1 528 ? 49.779 77.792 -18.911 1.00 12.35 ? 528 ASP A O 1 ATOM 4180 C CB . ASP A 1 528 ? 50.974 75.520 -17.388 1.00 13.64 ? 528 ASP A CB 1 ATOM 4181 C CG . ASP A 1 528 ? 49.902 74.448 -17.254 1.00 15.78 ? 528 ASP A CG 1 ATOM 4182 O OD1 . ASP A 1 528 ? 48.905 74.514 -17.993 1.00 14.35 ? 528 ASP A OD1 1 ATOM 4183 O OD2 . ASP A 1 528 ? 50.065 73.541 -16.356 1.00 15.99 ? 528 ASP A OD2 1 ATOM 4184 N N . SER A 1 529 ? 49.612 76.261 -20.575 1.00 12.01 ? 529 SER A N 1 ATOM 4185 C CA . SER A 1 529 ? 48.534 76.907 -21.340 1.00 12.46 ? 529 SER A CA 1 ATOM 4186 C C . SER A 1 529 ? 47.172 76.880 -20.706 1.00 14.51 ? 529 SER A C 1 ATOM 4187 O O . SER A 1 529 ? 46.341 77.787 -20.963 1.00 14.16 ? 529 SER A O 1 ATOM 4188 C CB . SER A 1 529 ? 48.423 76.223 -22.686 1.00 14.29 ? 529 SER A CB 1 ATOM 4189 O OG . SER A 1 529 ? 49.601 76.515 -23.406 1.00 16.40 ? 529 SER A OG 1 ATOM 4190 N N . ARG A 1 530 ? 46.948 75.901 -19.823 1.00 13.09 ? 530 ARG A N 1 ATOM 4191 C CA . ARG A 1 530 ? 45.613 75.719 -19.267 1.00 13.29 ? 530 ARG A CA 1 ATOM 4192 C C . ARG A 1 530 ? 45.491 75.824 -17.756 1.00 12.51 ? 530 ARG A C 1 ATOM 4193 O O . ARG A 1 530 ? 44.460 75.498 -17.201 1.00 15.96 ? 530 ARG A O 1 ATOM 4194 C CB . ARG A 1 530 ? 45.020 74.389 -19.760 1.00 9.77 ? 530 ARG A CB 1 ATOM 4195 C CG . ARG A 1 530 ? 44.991 74.300 -21.315 1.00 9.97 ? 530 ARG A CG 1 ATOM 4196 C CD . ARG A 1 530 ? 44.370 73.065 -21.902 1.00 11.14 ? 530 ARG A CD 1 ATOM 4197 N NE . ARG A 1 530 ? 45.105 71.849 -21.530 1.00 12.35 ? 530 ARG A NE 1 ATOM 4198 C CZ . ARG A 1 530 ? 44.956 70.678 -22.114 1.00 13.69 ? 530 ARG A CZ 1 ATOM 4199 N NH1 . ARG A 1 530 ? 44.088 70.526 -23.106 1.00 15.08 ? 530 ARG A NH1 1 ATOM 4200 N NH2 . ARG A 1 530 ? 45.742 69.663 -21.759 1.00 15.55 ? 530 ARG A NH2 1 ATOM 4201 N N . TRP A 1 531 ? 46.500 76.297 -17.064 1.00 12.72 ? 531 TRP A N 1 ATOM 4202 C CA . TRP A 1 531 ? 46.356 76.481 -15.609 1.00 12.73 ? 531 TRP A CA 1 ATOM 4203 C C . TRP A 1 531 ? 47.319 77.571 -15.179 1.00 15.28 ? 531 TRP A C 1 ATOM 4204 O O . TRP A 1 531 ? 48.498 77.473 -15.500 1.00 15.73 ? 531 TRP A O 1 ATOM 4205 C CB . TRP A 1 531 ? 46.694 75.195 -14.832 1.00 14.31 ? 531 TRP A CB 1 ATOM 4206 C CG . TRP A 1 531 ? 46.617 75.494 -13.367 1.00 14.33 ? 531 TRP A CG 1 ATOM 4207 C CD1 . TRP A 1 531 ? 47.652 75.917 -12.568 1.00 15.91 ? 531 TRP A CD1 1 ATOM 4208 C CD2 . TRP A 1 531 ? 45.437 75.611 -12.577 1.00 16.47 ? 531 TRP A CD2 1 ATOM 4209 N NE1 . TRP A 1 531 ? 47.186 76.289 -11.341 1.00 17.42 ? 531 TRP A NE1 1 ATOM 4210 C CE2 . TRP A 1 531 ? 45.828 76.110 -11.311 1.00 15.85 ? 531 TRP A CE2 1 ATOM 4211 C CE3 . TRP A 1 531 ? 44.102 75.349 -12.813 1.00 16.23 ? 531 TRP A CE3 1 ATOM 4212 C CZ2 . TRP A 1 531 ? 44.912 76.347 -10.287 1.00 17.98 ? 531 TRP A CZ2 1 ATOM 4213 C CZ3 . TRP A 1 531 ? 43.171 75.583 -11.792 1.00 18.03 ? 531 TRP A CZ3 1 ATOM 4214 C CH2 . TRP A 1 531 ? 43.581 76.075 -10.554 1.00 17.97 ? 531 TRP A CH2 1 ATOM 4215 N N . PRO A 1 532 ? 46.846 78.585 -14.417 1.00 16.34 ? 532 PRO A N 1 ATOM 4216 C CA . PRO A 1 532 ? 45.441 78.730 -13.979 1.00 18.61 ? 532 PRO A CA 1 ATOM 4217 C C . PRO A 1 532 ? 44.510 79.040 -15.166 1.00 19.18 ? 532 PRO A C 1 ATOM 4218 O O . PRO A 1 532 ? 43.282 78.959 -15.052 1.00 19.05 ? 532 PRO A O 1 ATOM 4219 C CB . PRO A 1 532 ? 45.504 79.899 -12.998 1.00 18.63 ? 532 PRO A CB 1 ATOM 4220 C CG . PRO A 1 532 ? 46.905 79.825 -12.420 1.00 19.14 ? 532 PRO A CG 1 ATOM 4221 C CD . PRO A 1 532 ? 47.701 79.556 -13.701 1.00 17.61 ? 532 PRO A CD 1 ATOM 4222 N N . GLY A 1 533 ? 45.117 79.357 -16.307 1.00 21.21 ? 533 GLY A N 1 ATOM 4223 C CA . GLY A 1 533 ? 44.365 79.638 -17.519 1.00 23.78 ? 533 GLY A CA 1 ATOM 4224 C C . GLY A 1 533 ? 44.195 81.114 -17.829 1.00 25.96 ? 533 GLY A C 1 ATOM 4225 O O . GLY A 1 533 ? 44.216 81.976 -16.939 1.00 26.05 ? 533 GLY A O 1 ATOM 4226 N N . SER A 1 534 ? 44.026 81.394 -19.117 1.00 29.32 ? 534 SER A N 1 ATOM 4227 C CA . SER A 1 534 ? 43.842 82.759 -19.632 1.00 31.88 ? 534 SER A CA 1 ATOM 4228 C C . SER A 1 534 ? 42.564 83.316 -19.029 1.00 32.68 ? 534 SER A C 1 ATOM 4229 O O . SER A 1 534 ? 41.526 82.655 -19.078 1.00 33.61 ? 534 SER A O 1 ATOM 4230 C CB . SER A 1 534 ? 43.741 82.730 -21.169 1.00 33.62 ? 534 SER A CB 1 ATOM 4231 O OG . SER A 1 534 ? 43.455 84.023 -21.727 1.00 37.48 ? 534 SER A OG 1 ATOM 4232 N N . GLY A 1 535 ? 42.626 84.521 -18.467 1.00 33.64 ? 535 GLY A N 1 ATOM 4233 C CA . GLY A 1 535 ? 41.436 85.099 -17.859 1.00 33.78 ? 535 GLY A CA 1 ATOM 4234 C C . GLY A 1 535 ? 41.295 84.736 -16.385 1.00 34.97 ? 535 GLY A C 1 ATOM 4235 O O . GLY A 1 535 ? 40.453 85.295 -15.647 1.00 34.36 ? 535 GLY A O 1 ATOM 4236 N N . VAL A 1 536 ? 42.108 83.775 -15.947 1.00 35.43 ? 536 VAL A N 1 ATOM 4237 C CA . VAL A 1 536 ? 42.103 83.367 -14.555 1.00 35.88 ? 536 VAL A CA 1 ATOM 4238 C C . VAL A 1 536 ? 43.290 84.093 -13.933 1.00 37.24 ? 536 VAL A C 1 ATOM 4239 O O . VAL A 1 536 ? 43.157 84.833 -12.950 1.00 37.04 ? 536 VAL A O 1 ATOM 4240 C CB . VAL A 1 536 ? 42.249 81.828 -14.416 1.00 36.07 ? 536 VAL A CB 1 ATOM 4241 C CG1 . VAL A 1 536 ? 42.231 81.421 -12.961 1.00 34.38 ? 536 VAL A CG1 1 ATOM 4242 C CG2 . VAL A 1 536 ? 41.091 81.150 -15.113 1.00 34.99 ? 536 VAL A CG2 1 ATOM 4243 N N . GLU A 1 537 ? 44.450 83.941 -14.550 1.00 37.97 ? 537 GLU A N 1 ATOM 4244 C CA . GLU A 1 537 ? 45.630 84.604 -14.038 1.00 39.85 ? 537 GLU A CA 1 ATOM 4245 C C . GLU A 1 537 ? 46.617 84.812 -15.192 1.00 40.21 ? 537 GLU A C 1 ATOM 4246 O O . GLU A 1 537 ? 46.866 83.887 -15.972 1.00 40.41 ? 537 GLU A O 1 ATOM 4247 C CB . GLU A 1 537 ? 46.203 83.725 -12.912 1.00 40.92 ? 537 GLU A CB 1 ATOM 4248 C CG . GLU A 1 537 ? 47.588 84.065 -12.368 1.00 43.20 ? 537 GLU A CG 1 ATOM 4249 C CD . GLU A 1 537 ? 47.922 83.207 -11.140 1.00 44.59 ? 537 GLU A CD 1 ATOM 4250 O OE1 . GLU A 1 537 ? 46.969 82.875 -10.390 1.00 45.77 ? 537 GLU A OE1 1 ATOM 4251 O OE2 . GLU A 1 537 ? 49.116 82.870 -10.927 1.00 44.66 ? 537 GLU A OE2 1 ATOM 4252 N N . ASP A 1 538 ? 47.130 86.035 -15.360 1.00 40.69 ? 538 ASP A N 1 ATOM 4253 C CA . ASP A 1 538 ? 48.115 86.218 -16.428 1.00 41.00 ? 538 ASP A CA 1 ATOM 4254 C C . ASP A 1 538 ? 49.457 85.871 -15.793 1.00 39.17 ? 538 ASP A C 1 ATOM 4255 O O . ASP A 1 538 ? 50.177 86.733 -15.261 1.00 39.65 ? 538 ASP A O 1 ATOM 4256 C CB . ASP A 1 538 ? 48.139 87.643 -16.981 1.00 43.28 ? 538 ASP A CB 1 ATOM 4257 C CG . ASP A 1 538 ? 49.058 87.761 -18.188 1.00 45.41 ? 538 ASP A CG 1 ATOM 4258 O OD1 . ASP A 1 538 ? 50.296 87.547 -18.024 1.00 45.89 ? 538 ASP A OD1 1 ATOM 4259 O OD2 . ASP A 1 538 ? 48.542 88.049 -19.299 1.00 46.95 ? 538 ASP A OD2 1 ATOM 4260 N N . SER A 1 539 ? 49.784 84.589 -15.849 1.00 36.41 ? 539 SER A N 1 ATOM 4261 C CA . SER A 1 539 ? 51.003 84.089 -15.217 1.00 33.86 ? 539 SER A CA 1 ATOM 4262 C C . SER A 1 539 ? 52.091 83.636 -16.188 1.00 31.11 ? 539 SER A C 1 ATOM 4263 O O . SER A 1 539 ? 53.241 83.466 -15.784 1.00 31.00 ? 539 SER A O 1 ATOM 4264 C CB . SER A 1 539 ? 50.636 82.912 -14.309 1.00 33.34 ? 539 SER A CB 1 ATOM 4265 O OG . SER A 1 539 ? 50.175 81.845 -15.117 1.00 35.44 ? 539 SER A OG 1 ATOM 4266 N N . ARG A 1 540 ? 51.717 83.453 -17.451 1.00 29.10 ? 540 ARG A N 1 ATOM 4267 C CA . ARG A 1 540 ? 52.627 82.977 -18.505 1.00 27.02 ? 540 ARG A CA 1 ATOM 4268 C C . ARG A 1 540 ? 53.680 83.980 -18.948 1.00 26.51 ? 540 ARG A C 1 ATOM 4269 O O . ARG A 1 540 ? 53.359 85.137 -19.233 1.00 26.84 ? 540 ARG A O 1 ATOM 4270 C CB . ARG A 1 540 ? 51.834 82.581 -19.731 1.00 24.55 ? 540 ARG A CB 1 ATOM 4271 C CG . ARG A 1 540 ? 51.035 81.314 -19.547 1.00 22.84 ? 540 ARG A CG 1 ATOM 4272 C CD . ARG A 1 540 ? 50.305 80.856 -20.834 1.00 19.01 ? 540 ARG A CD 1 ATOM 4273 N NE . ARG A 1 540 ? 51.160 80.222 -21.859 1.00 16.99 ? 540 ARG A NE 1 ATOM 4274 C CZ . ARG A 1 540 ? 50.748 79.754 -23.050 1.00 16.52 ? 540 ARG A CZ 1 ATOM 4275 N NH1 . ARG A 1 540 ? 49.468 79.808 -23.474 1.00 16.52 ? 540 ARG A NH1 1 ATOM 4276 N NH2 . ARG A 1 540 ? 51.644 79.232 -23.872 1.00 14.95 ? 540 ARG A NH2 1 ATOM 4277 N N . THR A 1 541 ? 54.921 83.527 -19.031 1.00 25.17 ? 541 THR A N 1 ATOM 4278 C CA . THR A 1 541 ? 55.981 84.420 -19.475 1.00 24.90 ? 541 THR A CA 1 ATOM 4279 C C . THR A 1 541 ? 56.027 84.451 -20.990 1.00 23.70 ? 541 THR A C 1 ATOM 4280 O O . THR A 1 541 ? 55.613 83.503 -21.666 1.00 24.18 ? 541 THR A O 1 ATOM 4281 C CB . THR A 1 541 ? 57.342 83.978 -18.954 1.00 25.27 ? 541 THR A CB 1 ATOM 4282 O OG1 . THR A 1 541 ? 57.709 82.775 -19.607 1.00 27.17 ? 541 THR A OG1 1 ATOM 4283 C CG2 . THR A 1 541 ? 57.280 83.704 -17.423 1.00 26.87 ? 541 THR A CG2 1 ATOM 4284 N N . THR A 1 542 ? 56.458 85.587 -21.521 1.00 21.37 ? 542 THR A N 1 ATOM 4285 C CA . THR A 1 542 ? 56.590 85.741 -22.964 1.00 18.35 ? 542 THR A CA 1 ATOM 4286 C C . THR A 1 542 ? 58.055 85.518 -23.296 1.00 15.08 ? 542 THR A C 1 ATOM 4287 O O . THR A 1 542 ? 58.909 86.049 -22.625 1.00 17.45 ? 542 THR A O 1 ATOM 4288 C CB . THR A 1 542 ? 56.225 87.199 -23.398 1.00 19.24 ? 542 THR A CB 1 ATOM 4289 O OG1 . THR A 1 542 ? 54.837 87.418 -23.119 1.00 20.26 ? 542 THR A OG1 1 ATOM 4290 C CG2 . THR A 1 542 ? 56.482 87.426 -24.902 1.00 17.64 ? 542 THR A CG2 1 ATOM 4291 N N . ILE A 1 543 ? 58.332 84.712 -24.301 1.00 13.72 ? 543 ILE A N 1 ATOM 4292 C CA . ILE A 1 543 ? 59.717 84.527 -24.733 1.00 12.44 ? 543 ILE A CA 1 ATOM 4293 C C . ILE A 1 543 ? 60.052 85.811 -25.542 1.00 13.94 ? 543 ILE A C 1 ATOM 4294 O O . ILE A 1 543 ? 59.443 86.071 -26.583 1.00 14.05 ? 543 ILE A O 1 ATOM 4295 C CB . ILE A 1 543 ? 59.834 83.279 -25.597 1.00 13.07 ? 543 ILE A CB 1 ATOM 4296 C CG1 . ILE A 1 543 ? 59.500 82.026 -24.739 1.00 13.47 ? 543 ILE A CG1 1 ATOM 4297 C CG2 . ILE A 1 543 ? 61.292 83.187 -26.189 1.00 13.63 ? 543 ILE A CG2 1 ATOM 4298 C CD1 . ILE A 1 543 ? 59.305 80.782 -25.575 1.00 15.34 ? 543 ILE A CD1 1 ATOM 4299 N N . ILE A 1 544 ? 61.029 86.545 -25.056 1.00 13.82 ? 544 ILE A N 1 ATOM 4300 C CA . ILE A 1 544 ? 61.398 87.825 -25.665 1.00 15.20 ? 544 ILE A CA 1 ATOM 4301 C C . ILE A 1 544 ? 62.611 87.664 -26.555 1.00 16.18 ? 544 ILE A C 1 ATOM 4302 O O . ILE A 1 544 ? 63.718 87.361 -26.073 1.00 18.38 ? 544 ILE A O 1 ATOM 4303 C CB . ILE A 1 544 ? 61.699 88.825 -24.566 1.00 16.19 ? 544 ILE A CB 1 ATOM 4304 C CG1 . ILE A 1 544 ? 60.428 89.036 -23.732 1.00 18.96 ? 544 ILE A CG1 1 ATOM 4305 C CG2 . ILE A 1 544 ? 62.195 90.146 -25.168 1.00 17.77 ? 544 ILE A CG2 1 ATOM 4306 C CD1 . ILE A 1 544 ? 60.633 90.001 -22.591 1.00 20.93 ? 544 ILE A CD1 1 ATOM 4307 N N . LEU A 1 545 ? 62.399 87.863 -27.852 1.00 15.89 ? 545 LEU A N 1 ATOM 4308 C CA . LEU A 1 545 ? 63.436 87.692 -28.861 1.00 15.85 ? 545 LEU A CA 1 ATOM 4309 C C . LEU A 1 545 ? 63.606 89.014 -29.558 1.00 15.86 ? 545 LEU A C 1 ATOM 4310 O O . LEU A 1 545 ? 62.747 89.873 -29.504 1.00 17.62 ? 545 LEU A O 1 ATOM 4311 C CB . LEU A 1 545 ? 63.027 86.618 -29.873 1.00 15.61 ? 545 LEU A CB 1 ATOM 4312 C CG . LEU A 1 545 ? 62.741 85.188 -29.341 1.00 16.46 ? 545 LEU A CG 1 ATOM 4313 C CD1 . LEU A 1 545 ? 62.155 84.332 -30.413 1.00 16.97 ? 545 LEU A CD1 1 ATOM 4314 C CD2 . LEU A 1 545 ? 64.059 84.565 -28.783 1.00 15.23 ? 545 LEU A CD2 1 ATOM 4315 N N . GLY A 1 546 ? 64.744 89.190 -30.188 1.00 14.68 ? 546 GLY A N 1 ATOM 4316 C CA . GLY A 1 546 ? 64.915 90.423 -30.924 1.00 14.40 ? 546 GLY A CA 1 ATOM 4317 C C . GLY A 1 546 ? 66.281 90.433 -31.527 1.00 14.47 ? 546 GLY A C 1 ATOM 4318 O O . GLY A 1 546 ? 67.222 89.905 -30.988 1.00 12.32 ? 546 GLY A O 1 ATOM 4319 N N . GLU A 1 547 ? 66.387 91.028 -32.692 1.00 15.39 ? 547 GLU A N 1 ATOM 4320 C CA . GLU A 1 547 ? 67.679 91.075 -33.343 1.00 18.48 ? 547 GLU A CA 1 ATOM 4321 C C . GLU A 1 547 ? 68.781 91.730 -32.520 1.00 19.63 ? 547 GLU A C 1 ATOM 4322 O O . GLU A 1 547 ? 69.962 91.368 -32.627 1.00 20.19 ? 547 GLU A O 1 ATOM 4323 C CB . GLU A 1 547 ? 67.501 91.798 -34.667 1.00 21.19 ? 547 GLU A CB 1 ATOM 4324 C CG . GLU A 1 547 ? 66.495 91.109 -35.620 1.00 26.60 ? 547 GLU A CG 1 ATOM 4325 C CD . GLU A 1 547 ? 64.985 91.200 -35.253 1.00 30.13 ? 547 GLU A CD 1 ATOM 4326 O OE1 . GLU A 1 547 ? 64.512 91.965 -34.345 1.00 26.54 ? 547 GLU A OE1 1 ATOM 4327 O OE2 . GLU A 1 547 ? 64.225 90.473 -35.956 1.00 34.20 ? 547 GLU A OE2 1 ATOM 4328 N N . ASP A 1 548 ? 68.384 92.689 -31.681 1.00 20.29 ? 548 ASP A N 1 ATOM 4329 C CA . ASP A 1 548 ? 69.302 93.446 -30.815 1.00 22.13 ? 548 ASP A CA 1 ATOM 4330 C C . ASP A 1 548 ? 69.294 92.930 -29.385 1.00 22.59 ? 548 ASP A C 1 ATOM 4331 O O . ASP A 1 548 ? 69.662 93.661 -28.437 1.00 24.99 ? 548 ASP A O 1 ATOM 4332 C CB . ASP A 1 548 ? 68.842 94.908 -30.762 1.00 22.22 ? 548 ASP A CB 1 ATOM 4333 C CG . ASP A 1 548 ? 69.106 95.640 -32.038 1.00 22.63 ? 548 ASP A CG 1 ATOM 4334 O OD1 . ASP A 1 548 ? 70.308 95.721 -32.386 1.00 25.56 ? 548 ASP A OD1 1 ATOM 4335 O OD2 . ASP A 1 548 ? 68.147 96.113 -32.680 1.00 24.47 ? 548 ASP A OD2 1 ATOM 4336 N N . ILE A 1 549 ? 68.858 91.698 -29.163 1.00 21.47 ? 549 ILE A N 1 ATOM 4337 C CA . ILE A 1 549 ? 68.837 91.231 -27.773 1.00 21.50 ? 549 ILE A CA 1 ATOM 4338 C C . ILE A 1 549 ? 69.064 89.719 -27.634 1.00 21.90 ? 549 ILE A C 1 ATOM 4339 O O . ILE A 1 549 ? 69.931 89.290 -26.909 1.00 23.97 ? 549 ILE A O 1 ATOM 4340 C CB . ILE A 1 549 ? 67.501 91.644 -27.004 1.00 22.58 ? 549 ILE A CB 1 ATOM 4341 C CG1 . ILE A 1 549 ? 67.526 91.061 -25.569 1.00 24.20 ? 549 ILE A CG1 1 ATOM 4342 C CG2 . ILE A 1 549 ? 66.236 91.117 -27.693 1.00 21.20 ? 549 ILE A CG2 1 ATOM 4343 C CD1 . ILE A 1 549 ? 67.811 92.066 -24.473 1.00 25.36 ? 549 ILE A CD1 1 ATOM 4344 N N . LEU A 1 550 ? 68.304 88.918 -28.356 1.00 21.25 ? 550 LEU A N 1 ATOM 4345 C CA . LEU A 1 550 ? 68.464 87.486 -28.224 1.00 19.35 ? 550 LEU A CA 1 ATOM 4346 C C . LEU A 1 550 ? 67.741 86.985 -29.437 1.00 17.95 ? 550 LEU A C 1 ATOM 4347 O O . LEU A 1 550 ? 66.538 87.187 -29.594 1.00 18.68 ? 550 LEU A O 1 ATOM 4348 C CB . LEU A 1 550 ? 67.809 86.993 -26.895 1.00 20.46 ? 550 LEU A CB 1 ATOM 4349 C CG . LEU A 1 550 ? 67.865 85.479 -26.627 1.00 20.41 ? 550 LEU A CG 1 ATOM 4350 C CD1 . LEU A 1 550 ? 69.307 85.033 -26.411 1.00 17.94 ? 550 LEU A CD1 1 ATOM 4351 C CD2 . LEU A 1 550 ? 66.981 85.108 -25.413 1.00 17.93 ? 550 LEU A CD2 1 ATOM 4352 N N . PRO A 1 551 ? 68.466 86.324 -30.333 1.00 15.73 ? 551 PRO A N 1 ATOM 4353 C CA . PRO A 1 551 ? 67.791 85.838 -31.532 1.00 15.03 ? 551 PRO A CA 1 ATOM 4354 C C . PRO A 1 551 ? 67.010 84.522 -31.405 1.00 15.44 ? 551 PRO A C 1 ATOM 4355 O O . PRO A 1 551 ? 66.140 84.214 -32.252 1.00 15.28 ? 551 PRO A O 1 ATOM 4356 C CB . PRO A 1 551 ? 68.918 85.754 -32.560 1.00 18.24 ? 551 PRO A CB 1 ATOM 4357 C CG . PRO A 1 551 ? 70.142 85.655 -31.807 1.00 18.82 ? 551 PRO A CG 1 ATOM 4358 C CD . PRO A 1 551 ? 69.935 86.367 -30.506 1.00 17.33 ? 551 PRO A CD 1 ATOM 4359 N N . SER A 1 552 ? 67.343 83.703 -30.409 1.00 14.52 ? 552 SER A N 1 ATOM 4360 C CA . SER A 1 552 ? 66.614 82.452 -30.342 1.00 15.03 ? 552 SER A CA 1 ATOM 4361 C C . SER A 1 552 ? 66.479 81.919 -28.917 1.00 12.94 ? 552 SER A C 1 ATOM 4362 O O . SER A 1 552 ? 67.149 82.399 -28.008 1.00 13.05 ? 552 SER A O 1 ATOM 4363 C CB . SER A 1 552 ? 67.283 81.413 -31.224 1.00 13.38 ? 552 SER A CB 1 ATOM 4364 O OG . SER A 1 552 ? 68.438 80.840 -30.678 1.00 16.88 ? 552 SER A OG 1 ATOM 4365 N N . LYS A 1 553 ? 65.613 80.910 -28.753 1.00 13.23 ? 553 LYS A N 1 ATOM 4366 C CA . LYS A 1 553 ? 65.364 80.328 -27.440 1.00 12.71 ? 553 LYS A CA 1 ATOM 4367 C C . LYS A 1 553 ? 65.070 78.832 -27.502 1.00 11.20 ? 553 LYS A C 1 ATOM 4368 O O . LYS A 1 553 ? 64.324 78.352 -28.371 1.00 11.84 ? 553 LYS A O 1 ATOM 4369 C CB . LYS A 1 553 ? 64.164 81.046 -26.803 1.00 14.29 ? 553 LYS A CB 1 ATOM 4370 C CG . LYS A 1 553 ? 63.632 80.333 -25.542 1.00 14.19 ? 553 LYS A CG 1 ATOM 4371 C CD . LYS A 1 553 ? 64.642 80.445 -24.442 1.00 14.99 ? 553 LYS A CD 1 ATOM 4372 C CE . LYS A 1 553 ? 64.710 81.899 -23.873 1.00 14.80 ? 553 LYS A CE 1 ATOM 4373 N NZ . LYS A 1 553 ? 65.937 82.163 -23.057 1.00 17.30 ? 553 LYS A NZ 1 ATOM 4374 N N . HIS A 1 554 ? 65.733 78.094 -26.620 1.00 11.56 ? 554 HIS A N 1 ATOM 4375 C CA . HIS A 1 554 ? 65.507 76.647 -26.517 1.00 11.42 ? 554 HIS A CA 1 ATOM 4376 C C . HIS A 1 554 ? 64.306 76.363 -25.604 1.00 11.94 ? 554 HIS A C 1 ATOM 4377 O O . HIS A 1 554 ? 64.169 76.994 -24.562 1.00 13.13 ? 554 HIS A O 1 ATOM 4378 C CB . HIS A 1 554 ? 66.735 75.931 -25.926 1.00 13.88 ? 554 HIS A CB 1 ATOM 4379 C CG . HIS A 1 554 ? 67.828 75.677 -26.911 1.00 16.32 ? 554 HIS A CG 1 ATOM 4380 N ND1 . HIS A 1 554 ? 68.493 76.702 -27.554 1.00 18.71 ? 554 HIS A ND1 1 ATOM 4381 C CD2 . HIS A 1 554 ? 68.425 74.522 -27.307 1.00 19.14 ? 554 HIS A CD2 1 ATOM 4382 C CE1 . HIS A 1 554 ? 69.469 76.188 -28.284 1.00 18.96 ? 554 HIS A CE1 1 ATOM 4383 N NE2 . HIS A 1 554 ? 69.452 74.869 -28.150 1.00 15.65 ? 554 HIS A NE2 1 ATOM 4384 N N . VAL A 1 555 ? 63.468 75.424 -26.061 1.00 10.10 ? 555 VAL A N 1 ATOM 4385 C CA . VAL A 1 555 ? 62.320 74.959 -25.296 1.00 10.86 ? 555 VAL A CA 1 ATOM 4386 C C . VAL A 1 555 ? 62.393 73.433 -25.266 1.00 10.36 ? 555 VAL A C 1 ATOM 4387 O O . VAL A 1 555 ? 62.889 72.810 -26.188 1.00 10.70 ? 555 VAL A O 1 ATOM 4388 C CB . VAL A 1 555 ? 60.937 75.446 -25.878 1.00 9.62 ? 555 VAL A CB 1 ATOM 4389 C CG1 . VAL A 1 555 ? 60.880 76.967 -25.759 1.00 13.38 ? 555 VAL A CG1 1 ATOM 4390 C CG2 . VAL A 1 555 ? 60.693 74.955 -27.277 1.00 11.34 ? 555 VAL A CG2 1 ATOM 4391 N N . VAL A 1 556 ? 61.775 72.811 -24.259 1.00 10.86 ? 556 VAL A N 1 ATOM 4392 C CA . VAL A 1 556 ? 61.844 71.358 -24.115 1.00 10.45 ? 556 VAL A CA 1 ATOM 4393 C C . VAL A 1 556 ? 60.453 70.834 -23.667 1.00 9.24 ? 556 VAL A C 1 ATOM 4394 O O . VAL A 1 556 ? 59.824 71.447 -22.770 1.00 10.50 ? 556 VAL A O 1 ATOM 4395 C CB . VAL A 1 556 ? 62.860 70.952 -22.982 1.00 10.56 ? 556 VAL A CB 1 ATOM 4396 C CG1 . VAL A 1 556 ? 62.814 69.406 -22.751 1.00 11.44 ? 556 VAL A CG1 1 ATOM 4397 C CG2 . VAL A 1 556 ? 64.342 71.363 -23.315 1.00 11.38 ? 556 VAL A CG2 1 ATOM 4398 N N . MET A 1 557 ? 60.038 69.757 -24.282 1.00 8.59 ? 557 MET A N 1 ATOM 4399 C CA . MET A 1 557 ? 58.771 69.107 -23.919 1.00 10.67 ? 557 MET A CA 1 ATOM 4400 C C . MET A 1 557 ? 59.067 67.737 -23.301 1.00 11.02 ? 557 MET A C 1 ATOM 4401 O O . MET A 1 557 ? 59.940 66.990 -23.762 1.00 9.69 ? 557 MET A O 1 ATOM 4402 C CB . MET A 1 557 ? 57.857 68.877 -25.133 1.00 11.97 ? 557 MET A CB 1 ATOM 4403 C CG . MET A 1 557 ? 56.824 69.998 -25.455 1.00 11.13 ? 557 MET A CG 1 ATOM 4404 S SD . MET A 1 557 ? 57.555 71.624 -25.644 1.00 11.37 ? 557 MET A SD 1 ATOM 4405 C CE . MET A 1 557 ? 58.678 71.532 -26.951 1.00 13.01 ? 557 MET A CE 1 ATOM 4406 N N . HIS A 1 558 ? 58.262 67.400 -22.300 1.00 10.51 ? 558 HIS A N 1 ATOM 4407 C CA . HIS A 1 558 ? 58.364 66.119 -21.634 1.00 10.62 ? 558 HIS A CA 1 ATOM 4408 C C . HIS A 1 558 ? 57.081 65.381 -21.878 1.00 8.79 ? 558 HIS A C 1 ATOM 4409 O O . HIS A 1 558 ? 56.004 65.972 -21.832 1.00 9.71 ? 558 HIS A O 1 ATOM 4410 C CB . HIS A 1 558 ? 58.488 66.353 -20.137 1.00 9.28 ? 558 HIS A CB 1 ATOM 4411 C CG . HIS A 1 558 ? 58.432 65.097 -19.323 1.00 9.82 ? 558 HIS A CG 1 ATOM 4412 N ND1 . HIS A 1 558 ? 57.506 64.910 -18.297 1.00 10.70 ? 558 HIS A ND1 1 ATOM 4413 C CD2 . HIS A 1 558 ? 59.189 63.976 -19.371 1.00 9.09 ? 558 HIS A CD2 1 ATOM 4414 C CE1 . HIS A 1 558 ? 57.699 63.705 -17.774 1.00 9.71 ? 558 HIS A CE1 1 ATOM 4415 N NE2 . HIS A 1 558 ? 58.706 63.117 -18.406 1.00 11.09 ? 558 HIS A NE2 1 ATOM 4416 N N . ASN A 1 559 ? 57.179 64.092 -22.046 1.00 9.09 ? 559 ASN A N 1 ATOM 4417 C CA . ASN A 1 559 ? 56.028 63.243 -22.269 1.00 9.05 ? 559 ASN A CA 1 ATOM 4418 C C . ASN A 1 559 ? 56.046 62.166 -21.195 1.00 8.16 ? 559 ASN A C 1 ATOM 4419 O O . ASN A 1 559 ? 56.763 61.208 -21.324 1.00 8.05 ? 559 ASN A O 1 ATOM 4420 C CB . ASN A 1 559 ? 56.115 62.618 -23.655 1.00 9.31 ? 559 ASN A CB 1 ATOM 4421 C CG . ASN A 1 559 ? 55.142 61.496 -23.878 1.00 8.32 ? 559 ASN A CG 1 ATOM 4422 O OD1 . ASN A 1 559 ? 53.990 61.490 -23.354 1.00 10.54 ? 559 ASN A OD1 1 ATOM 4423 N ND2 . ASN A 1 559 ? 55.537 60.562 -24.742 1.00 10.61 ? 559 ASN A ND2 1 ATOM 4424 N N . THR A 1 560 ? 55.201 62.301 -20.179 1.00 8.34 ? 560 THR A N 1 ATOM 4425 C CA . THR A 1 560 ? 55.171 61.313 -19.065 1.00 9.18 ? 560 THR A CA 1 ATOM 4426 C C . THR A 1 560 ? 54.586 59.943 -19.465 1.00 9.14 ? 560 THR A C 1 ATOM 4427 O O . THR A 1 560 ? 54.839 58.943 -18.783 1.00 11.08 ? 560 THR A O 1 ATOM 4428 C CB . THR A 1 560 ? 54.410 61.931 -17.893 1.00 9.57 ? 560 THR A CB 1 ATOM 4429 O OG1 . THR A 1 560 ? 54.723 61.199 -16.671 1.00 9.82 ? 560 THR A OG1 1 ATOM 4430 C CG2 . THR A 1 560 ? 52.911 61.823 -18.126 1.00 8.17 ? 560 THR A CG2 1 ATOM 4431 N N . LEU A 1 561 ? 53.840 59.861 -20.559 1.00 9.19 ? 561 LEU A N 1 ATOM 4432 C CA . LEU A 1 561 ? 53.254 58.592 -20.998 1.00 8.78 ? 561 LEU A CA 1 ATOM 4433 C C . LEU A 1 561 ? 54.300 57.647 -21.672 1.00 10.41 ? 561 LEU A C 1 ATOM 4434 O O . LEU A 1 561 ? 55.206 58.107 -22.386 1.00 9.17 ? 561 LEU A O 1 ATOM 4435 C CB . LEU A 1 561 ? 52.109 58.830 -22.029 1.00 9.27 ? 561 LEU A CB 1 ATOM 4436 C CG . LEU A 1 561 ? 51.017 59.778 -21.512 1.00 9.78 ? 561 LEU A CG 1 ATOM 4437 C CD1 . LEU A 1 561 ? 50.004 60.004 -22.651 1.00 11.42 ? 561 LEU A CD1 1 ATOM 4438 C CD2 . LEU A 1 561 ? 50.299 59.181 -20.248 1.00 9.91 ? 561 LEU A CD2 1 ATOM 4439 N N . PRO A 1 562 ? 54.131 56.337 -21.536 1.00 9.53 ? 562 PRO A N 1 ATOM 4440 C CA . PRO A 1 562 ? 55.067 55.391 -22.118 1.00 9.96 ? 562 PRO A CA 1 ATOM 4441 C C . PRO A 1 562 ? 54.917 55.056 -23.575 1.00 11.87 ? 562 PRO A C 1 ATOM 4442 O O . PRO A 1 562 ? 55.104 53.891 -23.960 1.00 11.12 ? 562 PRO A O 1 ATOM 4443 C CB . PRO A 1 562 ? 54.928 54.151 -21.238 1.00 9.43 ? 562 PRO A CB 1 ATOM 4444 C CG . PRO A 1 562 ? 53.387 54.220 -20.902 1.00 10.93 ? 562 PRO A CG 1 ATOM 4445 C CD . PRO A 1 562 ? 53.214 55.673 -20.581 1.00 8.93 ? 562 PRO A CD 1 ATOM 4446 N N . HIS A 1 563 ? 54.562 56.037 -24.415 1.00 9.50 ? 563 HIS A N 1 ATOM 4447 C CA . HIS A 1 563 ? 54.537 55.735 -25.858 1.00 11.68 ? 563 HIS A CA 1 ATOM 4448 C C . HIS A 1 563 ? 54.946 57.049 -26.544 1.00 10.44 ? 563 HIS A C 1 ATOM 4449 O O . HIS A 1 563 ? 54.803 58.122 -25.991 1.00 10.93 ? 563 HIS A O 1 ATOM 4450 C CB . HIS A 1 563 ? 53.149 55.252 -26.343 1.00 11.43 ? 563 HIS A CB 1 ATOM 4451 C CG . HIS A 1 563 ? 52.002 56.124 -25.912 1.00 13.74 ? 563 HIS A CG 1 ATOM 4452 N ND1 . HIS A 1 563 ? 51.185 55.797 -24.839 1.00 10.72 ? 563 HIS A ND1 1 ATOM 4453 C CD2 . HIS A 1 563 ? 51.517 57.289 -26.418 1.00 11.18 ? 563 HIS A CD2 1 ATOM 4454 C CE1 . HIS A 1 563 ? 50.250 56.723 -24.711 1.00 12.47 ? 563 HIS A CE1 1 ATOM 4455 N NE2 . HIS A 1 563 ? 50.428 57.648 -25.645 1.00 11.89 ? 563 HIS A NE2 1 ATOM 4456 N N . TRP A 1 564 ? 55.461 56.932 -27.767 1.00 11.05 ? 564 TRP A N 1 ATOM 4457 C CA . TRP A 1 564 ? 55.806 58.156 -28.529 1.00 11.47 ? 564 TRP A CA 1 ATOM 4458 C C . TRP A 1 564 ? 54.540 59.006 -28.641 1.00 12.04 ? 564 TRP A C 1 ATOM 4459 O O . TRP A 1 564 ? 53.427 58.495 -28.845 1.00 12.21 ? 564 TRP A O 1 ATOM 4460 C CB . TRP A 1 564 ? 56.280 57.782 -29.936 1.00 11.91 ? 564 TRP A CB 1 ATOM 4461 C CG . TRP A 1 564 ? 57.692 57.358 -30.013 1.00 11.09 ? 564 TRP A CG 1 ATOM 4462 C CD1 . TRP A 1 564 ? 58.161 56.085 -29.891 1.00 12.12 ? 564 TRP A CD1 1 ATOM 4463 C CD2 . TRP A 1 564 ? 58.847 58.211 -30.168 1.00 13.39 ? 564 TRP A CD2 1 ATOM 4464 N NE1 . TRP A 1 564 ? 59.534 56.084 -29.962 1.00 15.16 ? 564 TRP A NE1 1 ATOM 4465 C CE2 . TRP A 1 564 ? 59.981 57.368 -30.125 1.00 13.77 ? 564 TRP A CE2 1 ATOM 4466 C CE3 . TRP A 1 564 ? 59.037 59.615 -30.336 1.00 14.62 ? 564 TRP A CE3 1 ATOM 4467 C CZ2 . TRP A 1 564 ? 61.303 57.868 -30.242 1.00 14.42 ? 564 TRP A CZ2 1 ATOM 4468 C CZ3 . TRP A 1 564 ? 60.371 60.118 -30.451 1.00 14.30 ? 564 TRP A CZ3 1 ATOM 4469 C CH2 . TRP A 1 564 ? 61.471 59.243 -30.401 1.00 14.60 ? 564 TRP A CH2 1 ATOM 4470 N N . ARG A 1 565 ? 54.689 60.313 -28.525 1.00 9.69 ? 565 ARG A N 1 ATOM 4471 C CA . ARG A 1 565 ? 53.474 61.119 -28.585 1.00 11.94 ? 565 ARG A CA 1 ATOM 4472 C C . ARG A 1 565 ? 53.685 62.430 -29.339 1.00 11.22 ? 565 ARG A C 1 ATOM 4473 O O . ARG A 1 565 ? 54.728 63.045 -29.204 1.00 12.39 ? 565 ARG A O 1 ATOM 4474 C CB . ARG A 1 565 ? 53.001 61.422 -27.135 1.00 11.46 ? 565 ARG A CB 1 ATOM 4475 C CG . ARG A 1 565 ? 51.717 62.302 -27.123 1.00 13.00 ? 565 ARG A CG 1 ATOM 4476 C CD . ARG A 1 565 ? 50.785 62.224 -25.869 1.00 14.76 ? 565 ARG A CD 1 ATOM 4477 N NE . ARG A 1 565 ? 51.555 62.529 -24.687 1.00 15.33 ? 565 ARG A NE 1 ATOM 4478 C CZ . ARG A 1 565 ? 51.056 63.073 -23.593 1.00 14.34 ? 565 ARG A CZ 1 ATOM 4479 N NH1 . ARG A 1 565 ? 49.762 63.422 -23.524 1.00 14.67 ? 565 ARG A NH1 1 ATOM 4480 N NH2 . ARG A 1 565 ? 51.851 63.185 -22.558 1.00 12.81 ? 565 ARG A NH2 1 ATOM 4481 N N . GLU A 1 566 ? 52.723 62.783 -30.196 1.00 12.15 ? 566 GLU A N 1 ATOM 4482 C CA . GLU A 1 566 ? 52.766 64.115 -30.860 1.00 13.72 ? 566 GLU A CA 1 ATOM 4483 C C . GLU A 1 566 ? 51.628 64.927 -30.257 1.00 13.21 ? 566 GLU A C 1 ATOM 4484 O O . GLU A 1 566 ? 50.534 64.370 -30.001 1.00 14.74 ? 566 GLU A O 1 ATOM 4485 C CB . GLU A 1 566 ? 52.515 64.034 -32.381 1.00 13.17 ? 566 GLU A CB 1 ATOM 4486 C CG . GLU A 1 566 ? 53.607 63.359 -33.091 1.00 15.92 ? 566 GLU A CG 1 ATOM 4487 C CD . GLU A 1 566 ? 53.323 63.258 -34.576 1.00 19.69 ? 566 GLU A CD 1 ATOM 4488 O OE1 . GLU A 1 566 ? 52.181 62.932 -34.995 1.00 19.72 ? 566 GLU A OE1 1 ATOM 4489 O OE2 . GLU A 1 566 ? 54.279 63.534 -35.292 1.00 21.52 ? 566 GLU A OE2 1 ATOM 4490 N N . GLN A 1 567 ? 51.857 66.220 -30.000 1.00 11.84 ? 567 GLN A N 1 ATOM 4491 C CA . GLN A 1 567 ? 50.789 67.090 -29.489 1.00 11.37 ? 567 GLN A CA 1 ATOM 4492 C C . GLN A 1 567 ? 51.137 68.507 -29.905 1.00 13.03 ? 567 GLN A C 1 ATOM 4493 O O . GLN A 1 567 ? 52.325 68.885 -29.891 1.00 11.74 ? 567 GLN A O 1 ATOM 4494 C CB . GLN A 1 567 ? 50.725 66.979 -27.958 1.00 13.27 ? 567 GLN A CB 1 ATOM 4495 C CG . GLN A 1 567 ? 49.629 67.849 -27.392 1.00 14.15 ? 567 GLN A CG 1 ATOM 4496 C CD . GLN A 1 567 ? 49.962 68.336 -25.981 1.00 19.11 ? 567 GLN A CD 1 ATOM 4497 O OE1 . GLN A 1 567 ? 50.012 67.541 -25.032 1.00 17.09 ? 567 GLN A OE1 1 ATOM 4498 N NE2 . GLN A 1 567 ? 50.243 69.656 -25.838 1.00 21.10 ? 567 GLN A NE2 1 ATOM 4499 N N . LEU A 1 568 ? 50.136 69.271 -30.334 1.00 12.76 ? 568 LEU A N 1 ATOM 4500 C CA . LEU A 1 568 ? 50.453 70.662 -30.625 1.00 12.11 ? 568 LEU A CA 1 ATOM 4501 C C . LEU A 1 568 ? 50.766 71.364 -29.302 1.00 12.25 ? 568 LEU A C 1 ATOM 4502 O O . LEU A 1 568 ? 50.092 71.120 -28.260 1.00 13.87 ? 568 LEU A O 1 ATOM 4503 C CB . LEU A 1 568 ? 49.313 71.416 -31.293 1.00 12.75 ? 568 LEU A CB 1 ATOM 4504 C CG . LEU A 1 568 ? 48.929 70.960 -32.706 1.00 15.62 ? 568 LEU A CG 1 ATOM 4505 C CD1 . LEU A 1 568 ? 47.918 71.944 -33.250 1.00 17.02 ? 568 LEU A CD1 1 ATOM 4506 C CD2 . LEU A 1 568 ? 50.138 70.869 -33.598 1.00 14.25 ? 568 LEU A CD2 1 ATOM 4507 N N . VAL A 1 569 ? 51.805 72.177 -29.325 1.00 13.10 ? 569 VAL A N 1 ATOM 4508 C CA . VAL A 1 569 ? 52.163 72.963 -28.157 1.00 12.17 ? 569 VAL A CA 1 ATOM 4509 C C . VAL A 1 569 ? 52.270 74.455 -28.526 1.00 13.64 ? 569 VAL A C 1 ATOM 4510 O O . VAL A 1 569 ? 52.570 74.797 -29.692 1.00 13.50 ? 569 VAL A O 1 ATOM 4511 C CB . VAL A 1 569 ? 53.523 72.568 -27.473 1.00 10.69 ? 569 VAL A CB 1 ATOM 4512 C CG1 . VAL A 1 569 ? 53.384 71.188 -26.763 1.00 11.62 ? 569 VAL A CG1 1 ATOM 4513 C CG2 . VAL A 1 569 ? 54.707 72.586 -28.494 1.00 12.77 ? 569 VAL A CG2 1 ATOM 4514 N N . ASP A 1 570 ? 51.984 75.334 -27.583 1.00 12.94 ? 570 ASP A N 1 ATOM 4515 C CA . ASP A 1 570 ? 52.053 76.778 -27.837 1.00 13.67 ? 570 ASP A CA 1 ATOM 4516 C C . ASP A 1 570 ? 52.869 77.563 -26.819 1.00 15.22 ? 570 ASP A C 1 ATOM 4517 O O . ASP A 1 570 ? 52.931 77.208 -25.636 1.00 13.67 ? 570 ASP A O 1 ATOM 4518 C CB . ASP A 1 570 ? 50.640 77.425 -27.938 1.00 15.87 ? 570 ASP A CB 1 ATOM 4519 C CG . ASP A 1 570 ? 49.848 77.355 -26.659 1.00 19.61 ? 570 ASP A CG 1 ATOM 4520 O OD1 . ASP A 1 570 ? 49.653 76.236 -26.157 1.00 23.32 ? 570 ASP A OD1 1 ATOM 4521 O OD2 . ASP A 1 570 ? 49.403 78.392 -26.167 1.00 24.28 ? 570 ASP A OD2 1 ATOM 4522 N N . PHE A 1 571 ? 53.513 78.638 -27.284 1.00 12.13 ? 571 PHE A N 1 ATOM 4523 C CA . PHE A 1 571 ? 54.280 79.515 -26.446 1.00 12.76 ? 571 PHE A CA 1 ATOM 4524 C C . PHE A 1 571 ? 53.942 80.979 -26.808 1.00 13.14 ? 571 PHE A C 1 ATOM 4525 O O . PHE A 1 571 ? 53.580 81.237 -27.970 1.00 15.02 ? 571 PHE A O 1 ATOM 4526 C CB . PHE A 1 571 ? 55.793 79.331 -26.676 1.00 10.81 ? 571 PHE A CB 1 ATOM 4527 C CG . PHE A 1 571 ? 56.305 77.996 -26.265 1.00 11.25 ? 571 PHE A CG 1 ATOM 4528 C CD1 . PHE A 1 571 ? 56.309 76.924 -27.117 1.00 11.45 ? 571 PHE A CD1 1 ATOM 4529 C CD2 . PHE A 1 571 ? 56.732 77.825 -24.964 1.00 11.05 ? 571 PHE A CD2 1 ATOM 4530 C CE1 . PHE A 1 571 ? 56.724 75.655 -26.691 1.00 11.02 ? 571 PHE A CE1 1 ATOM 4531 C CE2 . PHE A 1 571 ? 57.150 76.573 -24.513 1.00 10.37 ? 571 PHE A CE2 1 ATOM 4532 C CZ . PHE A 1 571 ? 57.145 75.503 -25.352 1.00 12.88 ? 571 PHE A CZ 1 ATOM 4533 N N . TYR A 1 572 ? 54.085 81.887 -25.843 1.00 12.91 ? 572 TYR A N 1 ATOM 4534 C CA . TYR A 1 572 ? 53.889 83.329 -26.123 1.00 13.40 ? 572 TYR A CA 1 ATOM 4535 C C . TYR A 1 572 ? 55.257 83.845 -26.577 1.00 14.91 ? 572 TYR A C 1 ATOM 4536 O O . TYR A 1 572 ? 56.263 83.512 -25.966 1.00 15.06 ? 572 TYR A O 1 ATOM 4537 C CB . TYR A 1 572 ? 53.505 84.113 -24.902 1.00 15.23 ? 572 TYR A CB 1 ATOM 4538 C CG . TYR A 1 572 ? 52.075 83.925 -24.456 1.00 17.74 ? 572 TYR A CG 1 ATOM 4539 C CD1 . TYR A 1 572 ? 51.149 83.256 -25.239 1.00 17.57 ? 572 TYR A CD1 1 ATOM 4540 C CD2 . TYR A 1 572 ? 51.642 84.502 -23.268 1.00 20.25 ? 572 TYR A CD2 1 ATOM 4541 C CE1 . TYR A 1 572 ? 49.780 83.169 -24.843 1.00 21.22 ? 572 TYR A CE1 1 ATOM 4542 C CE2 . TYR A 1 572 ? 50.305 84.437 -22.869 1.00 22.56 ? 572 TYR A CE2 1 ATOM 4543 C CZ . TYR A 1 572 ? 49.389 83.769 -23.666 1.00 21.70 ? 572 TYR A CZ 1 ATOM 4544 O OH . TYR A 1 572 ? 48.073 83.715 -23.204 1.00 22.02 ? 572 TYR A OH 1 ATOM 4545 N N . VAL A 1 573 ? 55.317 84.690 -27.623 1.00 14.57 ? 573 VAL A N 1 ATOM 4546 C CA . VAL A 1 573 ? 56.600 85.214 -28.147 1.00 14.57 ? 573 VAL A CA 1 ATOM 4547 C C . VAL A 1 573 ? 56.401 86.679 -28.417 1.00 15.95 ? 573 VAL A C 1 ATOM 4548 O O . VAL A 1 573 ? 55.261 87.088 -28.708 1.00 16.60 ? 573 VAL A O 1 ATOM 4549 C CB . VAL A 1 573 ? 57.046 84.504 -29.430 1.00 13.65 ? 573 VAL A CB 1 ATOM 4550 C CG1 . VAL A 1 573 ? 57.536 83.111 -29.118 1.00 15.40 ? 573 VAL A CG1 1 ATOM 4551 C CG2 . VAL A 1 573 ? 55.906 84.445 -30.438 1.00 14.43 ? 573 VAL A CG2 1 ATOM 4552 N N . SER A 1 574 ? 57.481 87.474 -28.365 1.00 15.54 ? 574 SER A N 1 ATOM 4553 C CA . SER A 1 574 ? 57.382 88.939 -28.505 1.00 14.53 ? 574 SER A CA 1 ATOM 4554 C C . SER A 1 574 ? 57.317 89.447 -29.960 1.00 14.92 ? 574 SER A C 1 ATOM 4555 O O . SER A 1 574 ? 57.193 90.651 -30.162 1.00 16.44 ? 574 SER A O 1 ATOM 4556 C CB . SER A 1 574 ? 58.531 89.621 -27.768 1.00 16.78 ? 574 SER A CB 1 ATOM 4557 O OG . SER A 1 574 ? 59.758 89.270 -28.405 1.00 16.24 ? 574 SER A OG 1 ATOM 4558 N N . SER A 1 575 ? 57.350 88.532 -30.922 1.00 14.95 ? 575 SER A N 1 ATOM 4559 C CA . SER A 1 575 ? 57.264 88.865 -32.370 1.00 17.17 ? 575 SER A CA 1 ATOM 4560 C C . SER A 1 575 ? 56.483 87.805 -33.123 1.00 15.88 ? 575 SER A C 1 ATOM 4561 O O . SER A 1 575 ? 56.476 86.633 -32.750 1.00 16.63 ? 575 SER A O 1 ATOM 4562 C CB . SER A 1 575 ? 58.693 88.950 -32.992 1.00 18.41 ? 575 SER A CB 1 ATOM 4563 O OG . SER A 1 575 ? 58.650 89.087 -34.412 1.00 18.93 ? 575 SER A OG 1 ATOM 4564 N N . PRO A 1 576 ? 55.760 88.201 -34.164 1.00 16.31 ? 576 PRO A N 1 ATOM 4565 C CA . PRO A 1 576 ? 55.022 87.189 -34.927 1.00 15.26 ? 576 PRO A CA 1 ATOM 4566 C C . PRO A 1 576 ? 55.928 86.486 -35.909 1.00 14.61 ? 576 PRO A C 1 ATOM 4567 O O . PRO A 1 576 ? 55.567 85.500 -36.556 1.00 14.73 ? 576 PRO A O 1 ATOM 4568 C CB . PRO A 1 576 ? 53.944 87.993 -35.672 1.00 15.52 ? 576 PRO A CB 1 ATOM 4569 C CG . PRO A 1 576 ? 54.596 89.372 -35.844 1.00 17.41 ? 576 PRO A CG 1 ATOM 4570 C CD . PRO A 1 576 ? 55.383 89.587 -34.542 1.00 16.06 ? 576 PRO A CD 1 ATOM 4571 N N . PHE A 1 577 ? 57.129 87.023 -36.066 1.00 14.64 ? 577 PHE A N 1 ATOM 4572 C CA . PHE A 1 577 ? 58.033 86.466 -37.018 1.00 17.24 ? 577 PHE A CA 1 ATOM 4573 C C . PHE A 1 577 ? 58.990 85.512 -36.374 1.00 17.15 ? 577 PHE A C 1 ATOM 4574 O O . PHE A 1 577 ? 60.171 85.829 -36.180 1.00 18.06 ? 577 PHE A O 1 ATOM 4575 C CB . PHE A 1 577 ? 58.750 87.629 -37.710 1.00 18.85 ? 577 PHE A CB 1 ATOM 4576 C CG . PHE A 1 577 ? 57.786 88.630 -38.316 1.00 21.89 ? 577 PHE A CG 1 ATOM 4577 C CD1 . PHE A 1 577 ? 56.782 88.205 -39.176 1.00 22.58 ? 577 PHE A CD1 1 ATOM 4578 C CD2 . PHE A 1 577 ? 57.861 89.967 -37.980 1.00 23.34 ? 577 PHE A CD2 1 ATOM 4579 C CE1 . PHE A 1 577 ? 55.858 89.095 -39.703 1.00 23.11 ? 577 PHE A CE1 1 ATOM 4580 C CE2 . PHE A 1 577 ? 56.924 90.897 -38.500 1.00 26.02 ? 577 PHE A CE2 1 ATOM 4581 C CZ . PHE A 1 577 ? 55.923 90.440 -39.366 1.00 26.03 ? 577 PHE A CZ 1 ATOM 4582 N N . VAL A 1 578 ? 58.478 84.312 -36.108 1.00 16.63 ? 578 VAL A N 1 ATOM 4583 C CA . VAL A 1 578 ? 59.280 83.323 -35.395 1.00 15.86 ? 578 VAL A CA 1 ATOM 4584 C C . VAL A 1 578 ? 59.160 81.987 -36.071 1.00 14.92 ? 578 VAL A C 1 ATOM 4585 O O . VAL A 1 578 ? 58.085 81.631 -36.550 1.00 16.45 ? 578 VAL A O 1 ATOM 4586 C CB . VAL A 1 578 ? 58.805 83.176 -33.903 1.00 14.60 ? 578 VAL A CB 1 ATOM 4587 C CG1 . VAL A 1 578 ? 59.643 82.088 -33.188 1.00 12.51 ? 578 VAL A CG1 1 ATOM 4588 C CG2 . VAL A 1 578 ? 58.936 84.398 -33.209 1.00 14.34 ? 578 VAL A CG2 1 ATOM 4589 N N . SER A 1 579 ? 60.278 81.288 -36.185 1.00 14.49 ? 579 SER A N 1 ATOM 4590 C CA . SER A 1 579 ? 60.204 79.948 -36.761 1.00 15.67 ? 579 SER A CA 1 ATOM 4591 C C . SER A 1 579 ? 60.804 78.910 -35.786 1.00 14.28 ? 579 SER A C 1 ATOM 4592 O O . SER A 1 579 ? 61.584 79.242 -34.882 1.00 16.18 ? 579 SER A O 1 ATOM 4593 C CB . SER A 1 579 ? 60.863 79.852 -38.141 1.00 18.83 ? 579 SER A CB 1 ATOM 4594 O OG . SER A 1 579 ? 62.073 80.540 -38.151 1.00 22.71 ? 579 SER A OG 1 ATOM 4595 N N . VAL A 1 580 ? 60.448 77.659 -36.043 1.00 15.30 ? 580 VAL A N 1 ATOM 4596 C CA . VAL A 1 580 ? 60.834 76.571 -35.154 1.00 13.68 ? 580 VAL A CA 1 ATOM 4597 C C . VAL A 1 580 ? 61.681 75.521 -35.871 1.00 13.27 ? 580 VAL A C 1 ATOM 4598 O O . VAL A 1 580 ? 61.441 75.198 -37.017 1.00 14.46 ? 580 VAL A O 1 ATOM 4599 C CB . VAL A 1 580 ? 59.522 75.878 -34.631 1.00 13.00 ? 580 VAL A CB 1 ATOM 4600 C CG1 . VAL A 1 580 ? 59.861 74.691 -33.656 1.00 12.13 ? 580 VAL A CG1 1 ATOM 4601 C CG2 . VAL A 1 580 ? 58.587 76.932 -34.003 1.00 13.69 ? 580 VAL A CG2 1 ATOM 4602 N N . THR A 1 581 ? 62.704 75.060 -35.149 1.00 13.61 ? 581 THR A N 1 ATOM 4603 C CA . THR A 1 581 ? 63.561 73.979 -35.614 1.00 13.73 ? 581 THR A CA 1 ATOM 4604 C C . THR A 1 581 ? 63.738 72.944 -34.497 1.00 14.25 ? 581 THR A C 1 ATOM 4605 O O . THR A 1 581 ? 63.552 73.287 -33.315 1.00 14.99 ? 581 THR A O 1 ATOM 4606 C CB . THR A 1 581 ? 64.978 74.451 -36.018 1.00 13.29 ? 581 THR A CB 1 ATOM 4607 O OG1 . THR A 1 581 ? 65.528 75.332 -35.040 1.00 15.83 ? 581 THR A OG1 1 ATOM 4608 C CG2 . THR A 1 581 ? 64.893 75.196 -37.372 1.00 13.42 ? 581 THR A CG2 1 ATOM 4609 N N . ASP A 1 582 ? 64.113 71.712 -34.849 1.00 15.76 ? 582 ASP A N 1 ATOM 4610 C CA . ASP A 1 582 ? 64.368 70.668 -33.817 1.00 17.89 ? 582 ASP A CA 1 ATOM 4611 C C . ASP A 1 582 ? 65.868 70.714 -33.553 1.00 18.39 ? 582 ASP A C 1 ATOM 4612 O O . ASP A 1 582 ? 66.549 71.589 -34.083 1.00 18.08 ? 582 ASP A O 1 ATOM 4613 C CB . ASP A 1 582 ? 63.941 69.270 -34.278 1.00 18.48 ? 582 ASP A CB 1 ATOM 4614 C CG . ASP A 1 582 ? 64.664 68.796 -35.527 1.00 21.20 ? 582 ASP A CG 1 ATOM 4615 O OD1 . ASP A 1 582 ? 65.709 69.368 -35.843 1.00 20.52 ? 582 ASP A OD1 1 ATOM 4616 O OD2 . ASP A 1 582 ? 64.161 67.832 -36.156 1.00 22.06 ? 582 ASP A OD2 1 ATOM 4617 N N . LEU A 1 583 ? 66.440 69.802 -32.766 1.00 21.27 ? 583 LEU A N 1 ATOM 4618 C CA . LEU A 1 583 ? 67.866 70.007 -32.570 1.00 23.55 ? 583 LEU A CA 1 ATOM 4619 C C . LEU A 1 583 ? 68.770 69.486 -33.669 1.00 23.51 ? 583 LEU A C 1 ATOM 4620 O O . LEU A 1 583 ? 69.987 69.548 -33.542 1.00 25.29 ? 583 LEU A O 1 ATOM 4621 C CB . LEU A 1 583 ? 68.364 69.588 -31.159 1.00 24.93 ? 583 LEU A CB 1 ATOM 4622 C CG . LEU A 1 583 ? 69.293 70.662 -30.515 1.00 24.06 ? 583 LEU A CG 1 ATOM 4623 C CD1 . LEU A 1 583 ? 68.497 71.965 -30.405 1.00 24.35 ? 583 LEU A CD1 1 ATOM 4624 C CD2 . LEU A 1 583 ? 69.822 70.339 -29.113 1.00 25.50 ? 583 LEU A CD2 1 ATOM 4625 N N . ALA A 1 584 ? 68.175 68.956 -34.751 1.00 22.03 ? 584 ALA A N 1 ATOM 4626 C CA . ALA A 1 584 ? 69.005 68.587 -35.909 1.00 19.11 ? 584 ALA A CA 1 ATOM 4627 C C . ALA A 1 584 ? 68.879 69.814 -36.874 1.00 18.49 ? 584 ALA A C 1 ATOM 4628 O O . ALA A 1 584 ? 69.326 69.786 -38.021 1.00 16.67 ? 584 ALA A O 1 ATOM 4629 C CB . ALA A 1 584 ? 68.492 67.330 -36.585 1.00 20.47 ? 584 ALA A CB 1 ATOM 4630 N N . ASN A 1 585 ? 68.241 70.873 -36.401 1.00 17.36 ? 585 ASN A N 1 ATOM 4631 C CA . ASN A 1 585 ? 68.075 72.092 -37.184 1.00 16.99 ? 585 ASN A CA 1 ATOM 4632 C C . ASN A 1 585 ? 67.106 71.875 -38.330 1.00 18.08 ? 585 ASN A C 1 ATOM 4633 O O . ASN A 1 585 ? 67.176 72.570 -39.347 1.00 19.10 ? 585 ASN A O 1 ATOM 4634 C CB . ASN A 1 585 ? 69.410 72.571 -37.752 1.00 20.26 ? 585 ASN A CB 1 ATOM 4635 C CG . ASN A 1 585 ? 69.407 74.055 -38.036 1.00 23.11 ? 585 ASN A CG 1 ATOM 4636 O OD1 . ASN A 1 585 ? 68.765 74.829 -37.334 1.00 25.40 ? 585 ASN A OD1 1 ATOM 4637 N ND2 . ASN A 1 585 ? 70.147 74.464 -39.065 1.00 25.55 ? 585 ASN A ND2 1 ATOM 4638 N N . ASN A 1 586 ? 66.245 70.879 -38.193 1.00 15.95 ? 586 ASN A N 1 ATOM 4639 C CA . ASN A 1 586 ? 65.235 70.586 -39.194 1.00 18.16 ? 586 ASN A CA 1 ATOM 4640 C C . ASN A 1 586 ? 64.048 71.533 -38.999 1.00 18.44 ? 586 ASN A C 1 ATOM 4641 O O . ASN A 1 586 ? 63.509 71.637 -37.909 1.00 18.34 ? 586 ASN A O 1 ATOM 4642 C CB . ASN A 1 586 ? 64.680 69.169 -39.041 1.00 18.87 ? 586 ASN A CB 1 ATOM 4643 C CG . ASN A 1 586 ? 65.732 68.102 -39.208 1.00 22.01 ? 586 ASN A CG 1 ATOM 4644 O OD1 . ASN A 1 586 ? 66.519 68.141 -40.166 1.00 21.71 ? 586 ASN A OD1 1 ATOM 4645 N ND2 . ASN A 1 586 ? 65.750 67.110 -38.267 1.00 21.30 ? 586 ASN A ND2 1 ATOM 4646 N N . PRO A 1 587 ? 63.625 72.253 -40.048 1.00 17.30 ? 587 PRO A N 1 ATOM 4647 C CA . PRO A 1 587 ? 62.474 73.130 -39.808 1.00 17.74 ? 587 PRO A CA 1 ATOM 4648 C C . PRO A 1 587 ? 61.251 72.370 -39.310 1.00 17.17 ? 587 PRO A C 1 ATOM 4649 O O . PRO A 1 587 ? 61.026 71.196 -39.644 1.00 18.23 ? 587 PRO A O 1 ATOM 4650 C CB . PRO A 1 587 ? 62.191 73.751 -41.180 1.00 18.87 ? 587 PRO A CB 1 ATOM 4651 C CG . PRO A 1 587 ? 63.571 73.849 -41.777 1.00 20.38 ? 587 PRO A CG 1 ATOM 4652 C CD . PRO A 1 587 ? 64.201 72.480 -41.391 1.00 18.87 ? 587 PRO A CD 1 ATOM 4653 N N . VAL A 1 588 ? 60.461 73.058 -38.506 1.00 14.07 ? 588 VAL A N 1 ATOM 4654 C CA . VAL A 1 588 ? 59.224 72.513 -38.002 1.00 15.92 ? 588 VAL A CA 1 ATOM 4655 C C . VAL A 1 588 ? 58.059 73.445 -38.347 1.00 15.99 ? 588 VAL A C 1 ATOM 4656 O O . VAL A 1 588 ? 58.121 74.627 -38.088 1.00 15.23 ? 588 VAL A O 1 ATOM 4657 C CB . VAL A 1 588 ? 59.303 72.340 -36.478 1.00 15.76 ? 588 VAL A CB 1 ATOM 4658 C CG1 . VAL A 1 588 ? 57.919 71.889 -35.914 1.00 15.58 ? 588 VAL A CG1 1 ATOM 4659 C CG2 . VAL A 1 588 ? 60.428 71.341 -36.177 1.00 14.60 ? 588 VAL A CG2 1 ATOM 4660 N N . GLU A 1 589 ? 57.028 72.915 -38.982 1.00 16.53 ? 589 GLU A N 1 ATOM 4661 C CA . GLU A 1 589 ? 55.903 73.741 -39.355 1.00 17.78 ? 589 GLU A CA 1 ATOM 4662 C C . GLU A 1 589 ? 55.230 74.359 -38.120 1.00 16.52 ? 589 GLU A C 1 ATOM 4663 O O . GLU A 1 589 ? 54.961 73.660 -37.125 1.00 16.99 ? 589 GLU A O 1 ATOM 4664 C CB . GLU A 1 589 ? 54.884 72.927 -40.159 1.00 19.24 ? 589 GLU A CB 1 ATOM 4665 C CG . GLU A 1 589 ? 53.667 73.786 -40.518 1.00 23.82 ? 589 GLU A CG 1 ATOM 4666 C CD . GLU A 1 589 ? 52.554 73.055 -41.262 1.00 27.79 ? 589 GLU A CD 1 ATOM 4667 O OE1 . GLU A 1 589 ? 52.449 71.791 -41.228 1.00 32.10 ? 589 GLU A OE1 1 ATOM 4668 O OE2 . GLU A 1 589 ? 51.728 73.772 -41.879 1.00 30.70 ? 589 GLU A OE2 1 ATOM 4669 N N . ALA A 1 590 ? 54.929 75.648 -38.183 1.00 15.02 ? 590 ALA A N 1 ATOM 4670 C CA . ALA A 1 590 ? 54.345 76.362 -37.067 1.00 16.51 ? 590 ALA A CA 1 ATOM 4671 C C . ALA A 1 590 ? 53.264 77.257 -37.579 1.00 16.81 ? 590 ALA A C 1 ATOM 4672 O O . ALA A 1 590 ? 53.196 77.545 -38.812 1.00 15.67 ? 590 ALA A O 1 ATOM 4673 C CB . ALA A 1 590 ? 55.383 77.223 -36.385 1.00 14.13 ? 590 ALA A CB 1 ATOM 4674 N N . GLN A 1 591 ? 52.426 77.690 -36.638 1.00 16.38 ? 591 GLN A N 1 ATOM 4675 C CA . GLN A 1 591 ? 51.321 78.626 -36.928 1.00 16.43 ? 591 GLN A CA 1 ATOM 4676 C C . GLN A 1 591 ? 51.352 79.705 -35.859 1.00 16.33 ? 591 GLN A C 1 ATOM 4677 O O . GLN A 1 591 ? 51.497 79.403 -34.653 1.00 15.23 ? 591 GLN A O 1 ATOM 4678 C CB . GLN A 1 591 ? 49.968 77.907 -36.879 1.00 14.79 ? 591 GLN A CB 1 ATOM 4679 C CG . GLN A 1 591 ? 48.742 78.891 -36.857 1.00 14.92 ? 591 GLN A CG 1 ATOM 4680 C CD . GLN A 1 591 ? 47.389 78.168 -36.671 1.00 11.83 ? 591 GLN A CD 1 ATOM 4681 O OE1 . GLN A 1 591 ? 47.122 77.119 -37.265 1.00 14.93 ? 591 GLN A OE1 1 ATOM 4682 N NE2 . GLN A 1 591 ? 46.546 78.734 -35.829 1.00 15.71 ? 591 GLN A NE2 1 ATOM 4683 N N . VAL A 1 592 ? 51.215 80.969 -36.256 1.00 14.00 ? 592 VAL A N 1 ATOM 4684 C CA . VAL A 1 592 ? 51.192 82.044 -35.328 1.00 14.82 ? 592 VAL A CA 1 ATOM 4685 C C . VAL A 1 592 ? 49.777 82.647 -35.262 1.00 14.95 ? 592 VAL A C 1 ATOM 4686 O O . VAL A 1 592 ? 49.122 82.760 -36.264 1.00 15.22 ? 592 VAL A O 1 ATOM 4687 C CB . VAL A 1 592 ? 52.281 83.087 -35.663 1.00 13.74 ? 592 VAL A CB 1 ATOM 4688 C CG1 . VAL A 1 592 ? 52.082 84.283 -34.833 1.00 13.74 ? 592 VAL A CG1 1 ATOM 4689 C CG2 . VAL A 1 592 ? 53.638 82.514 -35.286 1.00 14.06 ? 592 VAL A CG2 1 ATOM 4690 N N . SER A 1 593 ? 49.295 82.947 -34.064 1.00 13.64 ? 593 SER A N 1 ATOM 4691 C CA . SER A 1 593 ? 47.960 83.496 -33.886 1.00 15.27 ? 593 SER A CA 1 ATOM 4692 C C . SER A 1 593 ? 48.062 84.611 -32.892 1.00 15.79 ? 593 SER A C 1 ATOM 4693 O O . SER A 1 593 ? 49.074 84.744 -32.144 1.00 16.90 ? 593 SER A O 1 ATOM 4694 C CB . SER A 1 593 ? 46.967 82.476 -33.278 1.00 17.25 ? 593 SER A CB 1 ATOM 4695 O OG . SER A 1 593 ? 46.720 81.329 -34.066 1.00 21.25 ? 593 SER A OG 1 ATOM 4696 N N . PRO A 1 594 ? 47.042 85.471 -32.830 1.00 16.15 ? 594 PRO A N 1 ATOM 4697 C CA . PRO A 1 594 ? 47.107 86.557 -31.844 1.00 15.57 ? 594 PRO A CA 1 ATOM 4698 C C . PRO A 1 594 ? 46.861 86.045 -30.385 1.00 14.72 ? 594 PRO A C 1 ATOM 4699 O O . PRO A 1 594 ? 46.353 84.907 -30.173 1.00 14.69 ? 594 PRO A O 1 ATOM 4700 C CB . PRO A 1 594 ? 45.940 87.472 -32.243 1.00 15.23 ? 594 PRO A CB 1 ATOM 4701 C CG . PRO A 1 594 ? 45.644 87.088 -33.672 1.00 17.76 ? 594 PRO A CG 1 ATOM 4702 C CD . PRO A 1 594 ? 45.888 85.633 -33.750 1.00 14.89 ? 594 PRO A CD 1 ATOM 4703 N N . VAL A 1 595 ? 47.196 86.874 -29.391 1.00 13.88 ? 595 VAL A N 1 ATOM 4704 C CA . VAL A 1 595 ? 46.888 86.536 -27.999 1.00 14.48 ? 595 VAL A CA 1 ATOM 4705 C C . VAL A 1 595 ? 45.580 87.281 -27.733 1.00 14.29 ? 595 VAL A C 1 ATOM 4706 O O . VAL A 1 595 ? 45.561 88.497 -27.632 1.00 14.27 ? 595 VAL A O 1 ATOM 4707 C CB . VAL A 1 595 ? 47.977 87.021 -26.967 1.00 14.44 ? 595 VAL A CB 1 ATOM 4708 C CG1 . VAL A 1 595 ? 47.504 86.725 -25.564 1.00 15.05 ? 595 VAL A CG1 1 ATOM 4709 C CG2 . VAL A 1 595 ? 49.293 86.243 -27.169 1.00 13.64 ? 595 VAL A CG2 1 ATOM 4710 N N . TRP A 1 596 ? 44.467 86.555 -27.638 1.00 15.06 ? 596 TRP A N 1 ATOM 4711 C CA . TRP A 1 596 ? 43.152 87.144 -27.381 1.00 16.54 ? 596 TRP A CA 1 ATOM 4712 C C . TRP A 1 596 ? 42.730 87.064 -25.900 1.00 17.53 ? 596 TRP A C 1 ATOM 4713 O O . TRP A 1 596 ? 42.837 86.000 -25.267 1.00 18.12 ? 596 TRP A O 1 ATOM 4714 C CB . TRP A 1 596 ? 42.072 86.408 -28.233 1.00 15.29 ? 596 TRP A CB 1 ATOM 4715 C CG . TRP A 1 596 ? 42.196 86.637 -29.734 1.00 15.73 ? 596 TRP A CG 1 ATOM 4716 C CD1 . TRP A 1 596 ? 42.674 85.758 -30.670 1.00 14.99 ? 596 TRP A CD1 1 ATOM 4717 C CD2 . TRP A 1 596 ? 41.866 87.841 -30.451 1.00 16.41 ? 596 TRP A CD2 1 ATOM 4718 N NE1 . TRP A 1 596 ? 42.653 86.325 -31.920 1.00 17.00 ? 596 TRP A NE1 1 ATOM 4719 C CE2 . TRP A 1 596 ? 42.174 87.606 -31.812 1.00 16.74 ? 596 TRP A CE2 1 ATOM 4720 C CE3 . TRP A 1 596 ? 41.350 89.079 -30.074 1.00 19.01 ? 596 TRP A CE3 1 ATOM 4721 C CZ2 . TRP A 1 596 ? 41.987 88.576 -32.798 1.00 18.37 ? 596 TRP A CZ2 1 ATOM 4722 C CZ3 . TRP A 1 596 ? 41.159 90.059 -31.074 1.00 18.04 ? 596 TRP A CZ3 1 ATOM 4723 C CH2 . TRP A 1 596 ? 41.484 89.784 -32.396 1.00 18.24 ? 596 TRP A CH2 1 ATOM 4724 N N . SER A 1 597 ? 42.241 88.160 -25.348 1.00 18.48 ? 597 SER A N 1 ATOM 4725 C CA . SER A 1 597 ? 41.738 88.136 -23.986 1.00 20.01 ? 597 SER A CA 1 ATOM 4726 C C . SER A 1 597 ? 40.336 88.720 -23.953 1.00 21.36 ? 597 SER A C 1 ATOM 4727 O O . SER A 1 597 ? 40.001 89.676 -24.663 1.00 21.70 ? 597 SER A O 1 ATOM 4728 C CB . SER A 1 597 ? 42.660 88.858 -23.006 1.00 22.20 ? 597 SER A CB 1 ATOM 4729 O OG . SER A 1 597 ? 42.746 90.235 -23.239 1.00 26.87 ? 597 SER A OG 1 ATOM 4730 N N . TRP A 1 598 ? 39.493 88.144 -23.119 1.00 21.50 ? 598 TRP A N 1 ATOM 4731 C CA . TRP A 1 598 ? 38.140 88.649 -23.046 1.00 23.00 ? 598 TRP A CA 1 ATOM 4732 C C . TRP A 1 598 ? 37.926 89.560 -21.843 1.00 25.41 ? 598 TRP A C 1 ATOM 4733 O O . TRP A 1 598 ? 38.483 89.364 -20.773 1.00 25.55 ? 598 TRP A O 1 ATOM 4734 C CB . TRP A 1 598 ? 37.167 87.471 -23.046 1.00 20.50 ? 598 TRP A CB 1 ATOM 4735 C CG . TRP A 1 598 ? 37.104 86.727 -24.335 1.00 19.20 ? 598 TRP A CG 1 ATOM 4736 C CD1 . TRP A 1 598 ? 38.036 85.860 -24.860 1.00 18.11 ? 598 TRP A CD1 1 ATOM 4737 C CD2 . TRP A 1 598 ? 36.061 86.809 -25.287 1.00 18.33 ? 598 TRP A CD2 1 ATOM 4738 N NE1 . TRP A 1 598 ? 37.629 85.390 -26.099 1.00 18.30 ? 598 TRP A NE1 1 ATOM 4739 C CE2 . TRP A 1 598 ? 36.415 85.966 -26.381 1.00 18.10 ? 598 TRP A CE2 1 ATOM 4740 C CE3 . TRP A 1 598 ? 34.850 87.519 -25.335 1.00 18.48 ? 598 TRP A CE3 1 ATOM 4741 C CZ2 . TRP A 1 598 ? 35.612 85.820 -27.491 1.00 18.45 ? 598 TRP A CZ2 1 ATOM 4742 C CZ3 . TRP A 1 598 ? 34.054 87.367 -26.455 1.00 18.64 ? 598 TRP A CZ3 1 ATOM 4743 C CH2 . TRP A 1 598 ? 34.442 86.522 -27.518 1.00 18.56 ? 598 TRP A CH2 1 ATOM 4744 N N . HIS A 1 599 ? 37.116 90.591 -22.031 1.00 29.77 ? 599 HIS A N 1 ATOM 4745 C CA . HIS A 1 599 ? 36.864 91.536 -20.956 1.00 35.16 ? 599 HIS A CA 1 ATOM 4746 C C . HIS A 1 599 ? 35.408 91.899 -20.894 1.00 37.96 ? 599 HIS A C 1 ATOM 4747 O O . HIS A 1 599 ? 34.729 91.895 -21.931 1.00 37.98 ? 599 HIS A O 1 ATOM 4748 C CB . HIS A 1 599 ? 37.672 92.818 -21.179 1.00 36.81 ? 599 HIS A CB 1 ATOM 4749 C CG . HIS A 1 599 ? 39.151 92.594 -21.192 1.00 39.35 ? 599 HIS A CG 1 ATOM 4750 N ND1 . HIS A 1 599 ? 39.875 92.339 -20.045 1.00 39.95 ? 599 HIS A ND1 1 ATOM 4751 C CD2 . HIS A 1 599 ? 40.030 92.500 -22.222 1.00 39.85 ? 599 HIS A CD2 1 ATOM 4752 C CE1 . HIS A 1 599 ? 41.133 92.090 -20.367 1.00 40.00 ? 599 HIS A CE1 1 ATOM 4753 N NE2 . HIS A 1 599 ? 41.255 92.179 -21.681 1.00 40.07 ? 599 HIS A NE2 1 ATOM 4754 N N . HIS A 1 600 ? 34.909 92.153 -19.685 1.00 41.92 ? 600 HIS A N 1 ATOM 4755 C CA . HIS A 1 600 ? 33.534 92.604 -19.587 1.00 45.50 ? 600 HIS A CA 1 ATOM 4756 C C . HIS A 1 600 ? 33.711 94.095 -19.673 1.00 46.70 ? 600 HIS A C 1 ATOM 4757 O O . HIS A 1 600 ? 34.339 94.714 -18.804 1.00 46.47 ? 600 HIS A O 1 ATOM 4758 C CB . HIS A 1 600 ? 32.818 92.284 -18.275 1.00 47.63 ? 600 HIS A CB 1 ATOM 4759 C CG . HIS A 1 600 ? 31.473 92.951 -18.186 1.00 51.12 ? 600 HIS A CG 1 ATOM 4760 N ND1 . HIS A 1 600 ? 30.588 92.975 -19.248 1.00 52.74 ? 600 HIS A ND1 1 ATOM 4761 C CD2 . HIS A 1 600 ? 30.892 93.682 -17.202 1.00 52.87 ? 600 HIS A CD2 1 ATOM 4762 C CE1 . HIS A 1 600 ? 29.525 93.691 -18.925 1.00 53.21 ? 600 HIS A CE1 1 ATOM 4763 N NE2 . HIS A 1 600 ? 29.683 94.134 -17.689 1.00 53.49 ? 600 HIS A NE2 1 ATOM 4764 N N . ASP A 1 601 ? 33.186 94.660 -20.747 1.00 47.62 ? 601 ASP A N 1 ATOM 4765 C CA . ASP A 1 601 ? 33.293 96.078 -20.973 1.00 49.25 ? 601 ASP A CA 1 ATOM 4766 C C . ASP A 1 601 ? 32.161 96.750 -20.193 1.00 49.69 ? 601 ASP A C 1 ATOM 4767 O O . ASP A 1 601 ? 31.025 96.785 -20.662 1.00 49.92 ? 601 ASP A O 1 ATOM 4768 C CB . ASP A 1 601 ? 33.151 96.352 -22.469 1.00 50.24 ? 601 ASP A CB 1 ATOM 4769 C CG . ASP A 1 601 ? 33.719 97.696 -22.875 1.00 51.24 ? 601 ASP A CG 1 ATOM 4770 O OD1 . ASP A 1 601 ? 33.639 98.651 -22.067 1.00 52.59 ? 601 ASP A OD1 1 ATOM 4771 O OD2 . ASP A 1 601 ? 34.230 97.796 -24.014 1.00 51.47 ? 601 ASP A OD2 1 ATOM 4772 N N . THR A 1 602 ? 32.469 97.268 -19.004 1.00 50.16 ? 602 THR A N 1 ATOM 4773 C CA . THR A 1 602 ? 31.454 97.930 -18.174 1.00 50.45 ? 602 THR A CA 1 ATOM 4774 C C . THR A 1 602 ? 30.923 99.194 -18.834 1.00 49.79 ? 602 THR A C 1 ATOM 4775 O O . THR A 1 602 ? 29.917 99.748 -18.393 1.00 50.60 ? 602 THR A O 1 ATOM 4776 C CB . THR A 1 602 ? 31.998 98.301 -16.765 1.00 51.31 ? 602 THR A CB 1 ATOM 4777 O OG1 . THR A 1 602 ? 33.285 98.934 -16.891 1.00 52.00 ? 602 THR A OG1 1 ATOM 4778 C CG2 . THR A 1 602 ? 32.095 97.061 -15.885 1.00 51.31 ? 602 THR A CG2 1 ATOM 4779 N N . LEU A 1 603 ? 31.608 99.648 -19.882 1.00 48.62 ? 603 LEU A N 1 ATOM 4780 C CA . LEU A 1 603 ? 31.198 100.841 -20.622 1.00 46.92 ? 603 LEU A CA 1 ATOM 4781 C C . LEU A 1 603 ? 30.179 100.483 -21.704 1.00 44.79 ? 603 LEU A C 1 ATOM 4782 O O . LEU A 1 603 ? 29.102 101.068 -21.762 1.00 44.84 ? 603 LEU A O 1 ATOM 4783 C CB . LEU A 1 603 ? 32.408 101.533 -21.270 1.00 48.24 ? 603 LEU A CB 1 ATOM 4784 C CG . LEU A 1 603 ? 33.351 102.343 -20.374 1.00 49.50 ? 603 LEU A CG 1 ATOM 4785 C CD1 . LEU A 1 603 ? 32.555 103.441 -19.669 1.00 50.46 ? 603 LEU A CD1 1 ATOM 4786 C CD2 . LEU A 1 603 ? 34.027 101.430 -19.350 1.00 50.76 ? 603 LEU A CD2 1 ATOM 4787 N N . THR A 1 604 ? 30.515 99.513 -22.554 1.00 41.83 ? 604 THR A N 1 ATOM 4788 C CA . THR A 1 604 ? 29.607 99.094 -23.622 1.00 38.07 ? 604 THR A CA 1 ATOM 4789 C C . THR A 1 604 ? 28.615 98.001 -23.226 1.00 35.28 ? 604 THR A C 1 ATOM 4790 O O . THR A 1 604 ? 27.664 97.750 -23.962 1.00 33.38 ? 604 THR A O 1 ATOM 4791 C CB . THR A 1 604 ? 30.381 98.571 -24.848 1.00 38.84 ? 604 THR A CB 1 ATOM 4792 O OG1 . THR A 1 604 ? 31.136 97.398 -24.480 1.00 38.47 ? 604 THR A OG1 1 ATOM 4793 C CG2 . THR A 1 604 ? 31.320 99.650 -25.382 1.00 38.73 ? 604 THR A CG2 1 ATOM 4794 N N . LYS A 1 605 ? 28.852 97.348 -22.087 1.00 33.18 ? 605 LYS A N 1 ATOM 4795 C CA . LYS A 1 605 ? 28.006 96.247 -21.601 1.00 32.10 ? 605 LYS A CA 1 ATOM 4796 C C . LYS A 1 605 ? 28.017 95.053 -22.554 1.00 31.09 ? 605 LYS A C 1 ATOM 4797 O O . LYS A 1 605 ? 26.978 94.457 -22.887 1.00 30.23 ? 605 LYS A O 1 ATOM 4798 C CB . LYS A 1 605 ? 26.570 96.711 -21.354 1.00 33.71 ? 605 LYS A CB 1 ATOM 4799 C CG . LYS A 1 605 ? 26.446 97.753 -20.257 1.00 36.39 ? 605 LYS A CG 1 ATOM 4800 C CD . LYS A 1 605 ? 27.086 97.266 -18.937 1.00 37.91 ? 605 LYS A CD 1 ATOM 4801 C CE . LYS A 1 605 ? 26.907 98.274 -17.813 1.00 39.25 ? 605 LYS A CE 1 ATOM 4802 N NZ . LYS A 1 605 ? 27.378 99.626 -18.217 1.00 40.21 ? 605 LYS A NZ 1 ATOM 4803 N N . THR A 1 606 ? 29.215 94.719 -23.013 1.00 28.43 ? 606 THR A N 1 ATOM 4804 C CA . THR A 1 606 ? 29.396 93.570 -23.895 1.00 26.66 ? 606 THR A CA 1 ATOM 4805 C C . THR A 1 606 ? 30.642 92.854 -23.401 1.00 24.86 ? 606 THR A C 1 ATOM 4806 O O . THR A 1 606 ? 31.456 93.434 -22.705 1.00 24.67 ? 606 THR A O 1 ATOM 4807 C CB . THR A 1 606 ? 29.623 93.983 -25.394 1.00 26.69 ? 606 THR A CB 1 ATOM 4808 O OG1 . THR A 1 606 ? 30.840 94.740 -25.507 1.00 25.80 ? 606 THR A OG1 1 ATOM 4809 C CG2 . THR A 1 606 ? 28.445 94.796 -25.921 1.00 26.25 ? 606 THR A CG2 1 ATOM 4810 N N . ILE A 1 607 ? 30.730 91.572 -23.720 1.00 24.35 ? 607 ILE A N 1 ATOM 4811 C CA . ILE A 1 607 ? 31.870 90.718 -23.383 1.00 22.22 ? 607 ILE A CA 1 ATOM 4812 C C . ILE A 1 607 ? 32.508 90.521 -24.760 1.00 22.36 ? 607 ILE A C 1 ATOM 4813 O O . ILE A 1 607 ? 31.934 89.879 -25.672 1.00 21.71 ? 607 ILE A O 1 ATOM 4814 C CB . ILE A 1 607 ? 31.362 89.386 -22.780 1.00 22.54 ? 607 ILE A CB 1 ATOM 4815 C CG1 . ILE A 1 607 ? 30.514 89.676 -21.515 1.00 22.40 ? 607 ILE A CG1 1 ATOM 4816 C CG2 . ILE A 1 607 ? 32.535 88.465 -22.450 1.00 22.30 ? 607 ILE A CG2 1 ATOM 4817 C CD1 . ILE A 1 607 ? 29.510 88.527 -21.173 1.00 23.37 ? 607 ILE A CD1 1 ATOM 4818 N N . HIS A 1 608 ? 33.698 91.087 -24.941 1.00 21.60 ? 608 HIS A N 1 ATOM 4819 C CA . HIS A 1 608 ? 34.315 91.006 -26.253 1.00 23.25 ? 608 HIS A CA 1 ATOM 4820 C C . HIS A 1 608 ? 35.795 90.836 -26.104 1.00 21.89 ? 608 HIS A C 1 ATOM 4821 O O . HIS A 1 608 ? 36.355 91.168 -25.079 1.00 22.25 ? 608 HIS A O 1 ATOM 4822 C CB . HIS A 1 608 ? 34.026 92.261 -27.042 1.00 26.18 ? 608 HIS A CB 1 ATOM 4823 C CG . HIS A 1 608 ? 34.633 93.469 -26.439 1.00 28.37 ? 608 HIS A CG 1 ATOM 4824 N ND1 . HIS A 1 608 ? 35.645 94.267 -26.860 1.00 30.31 ? 608 HIS A ND1 1 ATOM 4825 C CD2 . HIS A 1 608 ? 34.251 93.945 -25.204 1.00 30.35 ? 608 HIS A CD2 1 ATOM 4826 C CE1 . HIS A 1 608 ? 35.854 95.204 -25.871 1.00 31.43 ? 608 HIS A CE1 1 ATOM 4827 N NE2 . HIS A 1 608 ? 35.000 94.988 -24.884 1.00 31.69 ? 608 HIS A NE2 1 ATOM 4828 N N . PRO A 1 609 ? 36.434 90.328 -27.139 1.00 20.58 ? 609 PRO A N 1 ATOM 4829 C CA . PRO A 1 609 ? 37.874 90.087 -27.109 1.00 20.53 ? 609 PRO A CA 1 ATOM 4830 C C . PRO A 1 609 ? 38.754 91.265 -27.476 1.00 22.66 ? 609 PRO A C 1 ATOM 4831 O O . PRO A 1 609 ? 38.392 92.093 -28.352 1.00 24.07 ? 609 PRO A O 1 ATOM 4832 C CB . PRO A 1 609 ? 38.042 88.952 -28.096 1.00 21.54 ? 609 PRO A CB 1 ATOM 4833 C CG . PRO A 1 609 ? 37.040 89.324 -29.167 1.00 20.88 ? 609 PRO A CG 1 ATOM 4834 C CD . PRO A 1 609 ? 35.861 89.996 -28.457 1.00 20.77 ? 609 PRO A CD 1 ATOM 4835 N N . GLN A 1 610 ? 39.904 91.340 -26.813 1.00 20.94 ? 610 GLN A N 1 ATOM 4836 C CA . GLN A 1 610 ? 40.892 92.403 -27.099 1.00 20.88 ? 610 GLN A CA 1 ATOM 4837 C C . GLN A 1 610 ? 42.109 91.624 -27.536 1.00 18.98 ? 610 GLN A C 1 ATOM 4838 O O . GLN A 1 610 ? 42.392 90.579 -26.961 1.00 17.83 ? 610 GLN A O 1 ATOM 4839 C CB . GLN A 1 610 ? 41.259 93.199 -25.834 1.00 24.07 ? 610 GLN A CB 1 ATOM 4840 C CG . GLN A 1 610 ? 40.289 94.321 -25.468 1.00 31.24 ? 610 GLN A CG 1 ATOM 4841 C CD . GLN A 1 610 ? 40.714 95.089 -24.196 1.00 35.15 ? 610 GLN A CD 1 ATOM 4842 O OE1 . GLN A 1 610 ? 41.732 94.575 -23.492 1.00 38.22 ? 610 GLN A OE1 1 ATOM 4843 N NE2 . GLN A 1 610 ? 40.128 96.129 -23.855 1.00 36.57 ? 610 GLN A NE2 1 ATOM 4844 N N . GLY A 1 611 ? 42.798 92.094 -28.558 1.00 18.00 ? 611 GLY A N 1 ATOM 4845 C CA . GLY A 1 611 ? 43.985 91.428 -29.057 1.00 18.68 ? 611 GLY A CA 1 ATOM 4846 C C . GLY A 1 611 ? 45.237 92.118 -28.554 1.00 19.25 ? 611 GLY A C 1 ATOM 4847 O O . GLY A 1 611 ? 45.307 93.365 -28.511 1.00 19.78 ? 611 GLY A O 1 ATOM 4848 N N . SER A 1 612 ? 46.222 91.331 -28.139 1.00 18.72 ? 612 SER A N 1 ATOM 4849 C CA . SER A 1 612 ? 47.476 91.911 -27.652 1.00 18.92 ? 612 SER A CA 1 ATOM 4850 C C . SER A 1 612 ? 48.225 92.632 -28.747 1.00 18.87 ? 612 SER A C 1 ATOM 4851 O O . SER A 1 612 ? 48.278 92.171 -29.876 1.00 18.70 ? 612 SER A O 1 ATOM 4852 C CB . SER A 1 612 ? 48.426 90.824 -27.152 1.00 16.14 ? 612 SER A CB 1 ATOM 4853 O OG . SER A 1 612 ? 49.670 91.430 -26.791 1.00 18.47 ? 612 SER A OG 1 ATOM 4854 N N . THR A 1 613 ? 48.824 93.781 -28.401 1.00 20.71 ? 613 THR A N 1 ATOM 4855 C CA . THR A 1 613 ? 49.635 94.523 -29.390 1.00 22.51 ? 613 THR A CA 1 ATOM 4856 C C . THR A 1 613 ? 51.093 94.410 -28.930 1.00 23.40 ? 613 THR A C 1 ATOM 4857 O O . THR A 1 613 ? 51.967 95.167 -29.409 1.00 24.27 ? 613 THR A O 1 ATOM 4858 C CB . THR A 1 613 ? 49.358 96.044 -29.425 1.00 22.64 ? 613 THR A CB 1 ATOM 4859 O OG1 . THR A 1 613 ? 49.807 96.644 -28.185 1.00 24.97 ? 613 THR A OG1 1 ATOM 4860 C CG2 . THR A 1 613 ? 47.846 96.314 -29.594 1.00 21.92 ? 613 THR A CG2 1 ATOM 4861 N N . THR A 1 614 ? 51.375 93.503 -27.998 1.00 24.56 ? 614 THR A N 1 ATOM 4862 C CA . THR A 1 614 ? 52.759 93.375 -27.524 1.00 24.38 ? 614 THR A CA 1 ATOM 4863 C C . THR A 1 614 ? 53.265 91.938 -27.429 1.00 24.91 ? 614 THR A C 1 ATOM 4864 O O . THR A 1 614 ? 54.433 91.731 -27.075 1.00 25.60 ? 614 THR A O 1 ATOM 4865 C CB . THR A 1 614 ? 52.924 94.069 -26.186 1.00 26.08 ? 614 THR A CB 1 ATOM 4866 O OG1 . THR A 1 614 ? 52.187 93.361 -25.170 1.00 26.77 ? 614 THR A OG1 1 ATOM 4867 C CG2 . THR A 1 614 ? 52.381 95.484 -26.296 1.00 26.76 ? 614 THR A CG2 1 ATOM 4868 N N . LYS A 1 615 ? 52.415 90.956 -27.751 1.00 22.79 ? 615 LYS A N 1 ATOM 4869 C CA . LYS A 1 615 ? 52.823 89.551 -27.706 1.00 20.81 ? 615 LYS A CA 1 ATOM 4870 C C . LYS A 1 615 ? 51.901 88.669 -28.582 1.00 20.44 ? 615 LYS A C 1 ATOM 4871 O O . LYS A 1 615 ? 50.774 89.067 -28.892 1.00 18.88 ? 615 LYS A O 1 ATOM 4872 C CB . LYS A 1 615 ? 52.941 89.089 -26.222 1.00 21.28 ? 615 LYS A CB 1 ATOM 4873 C CG . LYS A 1 615 ? 51.659 88.782 -25.484 1.00 21.36 ? 615 LYS A CG 1 ATOM 4874 C CD . LYS A 1 615 ? 51.940 88.540 -23.979 1.00 21.75 ? 615 LYS A CD 1 ATOM 4875 C CE . LYS A 1 615 ? 50.691 88.008 -23.300 1.00 22.77 ? 615 LYS A CE 1 ATOM 4876 N NZ . LYS A 1 615 ? 50.663 88.140 -21.801 1.00 21.69 ? 615 LYS A NZ 1 ATOM 4877 N N . TYR A 1 616 ? 52.409 87.511 -29.020 1.00 18.08 ? 616 TYR A N 1 ATOM 4878 C CA . TYR A 1 616 ? 51.730 86.580 -29.945 1.00 16.64 ? 616 TYR A CA 1 ATOM 4879 C C . TYR A 1 616 ? 51.906 85.116 -29.544 1.00 17.97 ? 616 TYR A C 1 ATOM 4880 O O . TYR A 1 616 ? 52.796 84.835 -28.736 1.00 18.99 ? 616 TYR A O 1 ATOM 4881 C CB . TYR A 1 616 ? 52.329 86.747 -31.370 1.00 19.60 ? 616 TYR A CB 1 ATOM 4882 C CG . TYR A 1 616 ? 52.486 88.212 -31.765 1.00 22.33 ? 616 TYR A CG 1 ATOM 4883 C CD1 . TYR A 1 616 ? 53.613 88.926 -31.399 1.00 21.93 ? 616 TYR A CD1 1 ATOM 4884 C CD2 . TYR A 1 616 ? 51.416 88.911 -32.353 1.00 23.66 ? 616 TYR A CD2 1 ATOM 4885 C CE1 . TYR A 1 616 ? 53.687 90.332 -31.586 1.00 25.11 ? 616 TYR A CE1 1 ATOM 4886 C CE2 . TYR A 1 616 ? 51.471 90.297 -32.541 1.00 24.89 ? 616 TYR A CE2 1 ATOM 4887 C CZ . TYR A 1 616 ? 52.603 90.994 -32.154 1.00 26.26 ? 616 TYR A CZ 1 ATOM 4888 O OH . TYR A 1 616 ? 52.660 92.370 -32.325 1.00 30.83 ? 616 TYR A OH 1 ATOM 4889 N N . ARG A 1 617 ? 51.112 84.208 -30.121 1.00 14.58 ? 617 ARG A N 1 ATOM 4890 C CA . ARG A 1 617 ? 51.193 82.749 -29.835 1.00 15.88 ? 617 ARG A CA 1 ATOM 4891 C C . ARG A 1 617 ? 51.770 81.949 -31.005 1.00 15.61 ? 617 ARG A C 1 ATOM 4892 O O . ARG A 1 617 ? 51.263 82.075 -32.119 1.00 16.37 ? 617 ARG A O 1 ATOM 4893 C CB . ARG A 1 617 ? 49.805 82.125 -29.577 1.00 16.57 ? 617 ARG A CB 1 ATOM 4894 C CG . ARG A 1 617 ? 49.074 82.389 -28.288 1.00 20.05 ? 617 ARG A CG 1 ATOM 4895 C CD . ARG A 1 617 ? 47.650 81.673 -28.288 1.00 20.22 ? 617 ARG A CD 1 ATOM 4896 N NE . ARG A 1 617 ? 47.680 80.203 -28.291 1.00 20.46 ? 617 ARG A NE 1 ATOM 4897 C CZ . ARG A 1 617 ? 47.039 79.450 -29.189 1.00 20.91 ? 617 ARG A CZ 1 ATOM 4898 N NH1 . ARG A 1 617 ? 46.313 80.026 -30.151 1.00 20.77 ? 617 ARG A NH1 1 ATOM 4899 N NH2 . ARG A 1 617 ? 47.136 78.127 -29.172 1.00 19.03 ? 617 ARG A NH2 1 ATOM 4900 N N . ILE A 1 618 ? 52.805 81.125 -30.784 1.00 13.77 ? 618 ILE A N 1 ATOM 4901 C CA . ILE A 1 618 ? 53.305 80.253 -31.823 1.00 15.08 ? 618 ILE A CA 1 ATOM 4902 C C . ILE A 1 618 ? 52.919 78.854 -31.408 1.00 15.97 ? 618 ILE A C 1 ATOM 4903 O O . ILE A 1 618 ? 52.994 78.524 -30.216 1.00 17.19 ? 618 ILE A O 1 ATOM 4904 C CB . ILE A 1 618 ? 54.824 80.432 -32.065 1.00 14.63 ? 618 ILE A CB 1 ATOM 4905 C CG1 . ILE A 1 618 ? 55.215 79.617 -33.271 1.00 17.99 ? 618 ILE A CG1 1 ATOM 4906 C CG2 . ILE A 1 618 ? 55.662 80.092 -30.830 1.00 17.22 ? 618 ILE A CG2 1 ATOM 4907 C CD1 . ILE A 1 618 ? 56.442 80.066 -33.909 1.00 17.04 ? 618 ILE A CD1 1 ATOM 4908 N N . ILE A 1 619 ? 52.473 78.071 -32.382 1.00 14.58 ? 619 ILE A N 1 ATOM 4909 C CA . ILE A 1 619 ? 51.980 76.708 -32.188 1.00 14.42 ? 619 ILE A CA 1 ATOM 4910 C C . ILE A 1 619 ? 52.724 75.759 -33.105 1.00 12.96 ? 619 ILE A C 1 ATOM 4911 O O . ILE A 1 619 ? 52.886 76.060 -34.287 1.00 14.73 ? 619 ILE A O 1 ATOM 4912 C CB . ILE A 1 619 ? 50.441 76.649 -32.597 1.00 16.19 ? 619 ILE A CB 1 ATOM 4913 C CG1 . ILE A 1 619 ? 49.658 77.616 -31.747 1.00 18.89 ? 619 ILE A CG1 1 ATOM 4914 C CG2 . ILE A 1 619 ? 49.841 75.249 -32.491 1.00 16.74 ? 619 ILE A CG2 1 ATOM 4915 C CD1 . ILE A 1 619 ? 48.318 78.137 -32.427 1.00 18.90 ? 619 ILE A CD1 1 ATOM 4916 N N . PHE A 1 620 ? 53.169 74.606 -32.629 1.00 12.12 ? 620 PHE A N 1 ATOM 4917 C CA . PHE A 1 620 ? 53.779 73.632 -33.509 1.00 11.00 ? 620 PHE A CA 1 ATOM 4918 C C . PHE A 1 620 ? 53.615 72.257 -32.926 1.00 13.42 ? 620 PHE A C 1 ATOM 4919 O O . PHE A 1 620 ? 53.321 72.132 -31.732 1.00 12.89 ? 620 PHE A O 1 ATOM 4920 C CB . PHE A 1 620 ? 55.258 73.872 -33.763 1.00 11.96 ? 620 PHE A CB 1 ATOM 4921 C CG . PHE A 1 620 ? 56.094 73.821 -32.558 1.00 10.94 ? 620 PHE A CG 1 ATOM 4922 C CD1 . PHE A 1 620 ? 56.206 74.916 -31.734 1.00 9.47 ? 620 PHE A CD1 1 ATOM 4923 C CD2 . PHE A 1 620 ? 56.803 72.645 -32.234 1.00 12.00 ? 620 PHE A CD2 1 ATOM 4924 C CE1 . PHE A 1 620 ? 57.036 74.893 -30.555 1.00 13.25 ? 620 PHE A CE1 1 ATOM 4925 C CE2 . PHE A 1 620 ? 57.640 72.623 -31.044 1.00 11.62 ? 620 PHE A CE2 1 ATOM 4926 C CZ . PHE A 1 620 ? 57.740 73.731 -30.247 1.00 11.89 ? 620 PHE A CZ 1 ATOM 4927 N N . LYS A 1 621 ? 53.790 71.235 -33.743 1.00 13.04 ? 621 LYS A N 1 ATOM 4928 C CA . LYS A 1 621 ? 53.651 69.883 -33.262 1.00 14.30 ? 621 LYS A CA 1 ATOM 4929 C C . LYS A 1 621 ? 54.951 69.353 -32.682 1.00 14.03 ? 621 LYS A C 1 ATOM 4930 O O . LYS A 1 621 ? 55.973 69.244 -33.371 1.00 14.47 ? 621 LYS A O 1 ATOM 4931 C CB . LYS A 1 621 ? 53.153 69.012 -34.406 1.00 15.64 ? 621 LYS A CB 1 ATOM 4932 C CG . LYS A 1 621 ? 52.765 67.594 -33.992 1.00 18.25 ? 621 LYS A CG 1 ATOM 4933 C CD . LYS A 1 621 ? 51.865 67.014 -35.051 1.00 21.44 ? 621 LYS A CD 1 ATOM 4934 C CE . LYS A 1 621 ? 52.645 66.731 -36.326 1.00 21.96 ? 621 LYS A CE 1 ATOM 4935 N NZ . LYS A 1 621 ? 51.793 66.156 -37.493 1.00 25.01 ? 621 LYS A NZ 1 ATOM 4936 N N . ALA A 1 622 ? 54.923 69.048 -31.399 1.00 12.06 ? 622 ALA A N 1 ATOM 4937 C CA . ALA A 1 622 ? 56.105 68.452 -30.747 1.00 11.42 ? 622 ALA A CA 1 ATOM 4938 C C . ALA A 1 622 ? 55.962 66.945 -30.799 1.00 12.09 ? 622 ALA A C 1 ATOM 4939 O O . ALA A 1 622 ? 54.856 66.431 -30.620 1.00 13.11 ? 622 ALA A O 1 ATOM 4940 C CB . ALA A 1 622 ? 56.176 68.908 -29.304 1.00 12.00 ? 622 ALA A CB 1 ATOM 4941 N N . ARG A 1 623 ? 57.071 66.243 -30.999 1.00 11.50 ? 623 ARG A N 1 ATOM 4942 C CA . ARG A 1 623 ? 57.087 64.763 -31.059 1.00 12.25 ? 623 ARG A CA 1 ATOM 4943 C C . ARG A 1 623 ? 58.075 64.383 -29.934 1.00 13.67 ? 623 ARG A C 1 ATOM 4944 O O . ARG A 1 623 ? 59.266 64.762 -29.972 1.00 15.35 ? 623 ARG A O 1 ATOM 4945 C CB . ARG A 1 623 ? 57.591 64.241 -32.419 1.00 12.87 ? 623 ARG A CB 1 ATOM 4946 C CG . ARG A 1 623 ? 57.601 62.703 -32.523 1.00 16.02 ? 623 ARG A CG 1 ATOM 4947 C CD . ARG A 1 623 ? 57.561 62.135 -33.987 1.00 19.17 ? 623 ARG A CD 1 ATOM 4948 N NE . ARG A 1 623 ? 57.576 60.676 -33.992 1.00 19.36 ? 623 ARG A NE 1 ATOM 4949 C CZ . ARG A 1 623 ? 58.677 59.949 -33.910 1.00 20.10 ? 623 ARG A CZ 1 ATOM 4950 N NH1 . ARG A 1 623 ? 59.857 60.551 -33.855 1.00 22.88 ? 623 ARG A NH1 1 ATOM 4951 N NH2 . ARG A 1 623 ? 58.596 58.626 -33.774 1.00 18.51 ? 623 ARG A NH2 1 ATOM 4952 N N . VAL A 1 624 ? 57.586 63.631 -28.953 1.00 10.65 ? 624 VAL A N 1 ATOM 4953 C CA . VAL A 1 624 ? 58.412 63.319 -27.788 1.00 12.21 ? 624 VAL A CA 1 ATOM 4954 C C . VAL A 1 624 ? 58.459 61.839 -27.513 1.00 12.23 ? 624 VAL A C 1 ATOM 4955 O O . VAL A 1 624 ? 57.430 61.195 -27.575 1.00 11.02 ? 624 VAL A O 1 ATOM 4956 C CB . VAL A 1 624 ? 57.813 64.059 -26.570 1.00 11.37 ? 624 VAL A CB 1 ATOM 4957 C CG1 . VAL A 1 624 ? 58.837 64.042 -25.425 1.00 10.67 ? 624 VAL A CG1 1 ATOM 4958 C CG2 . VAL A 1 624 ? 57.486 65.549 -26.970 1.00 12.70 ? 624 VAL A CG2 1 ATOM 4959 N N . PRO A 1 625 ? 59.655 61.283 -27.207 1.00 11.79 ? 625 PRO A N 1 ATOM 4960 C CA . PRO A 1 625 ? 59.761 59.836 -26.937 1.00 10.97 ? 625 PRO A CA 1 ATOM 4961 C C . PRO A 1 625 ? 58.949 59.378 -25.717 1.00 11.57 ? 625 PRO A C 1 ATOM 4962 O O . PRO A 1 625 ? 58.519 60.204 -24.895 1.00 11.86 ? 625 PRO A O 1 ATOM 4963 C CB . PRO A 1 625 ? 61.281 59.604 -26.652 1.00 13.75 ? 625 PRO A CB 1 ATOM 4964 C CG . PRO A 1 625 ? 61.932 60.803 -27.225 1.00 12.79 ? 625 PRO A CG 1 ATOM 4965 C CD . PRO A 1 625 ? 60.946 61.950 -27.037 1.00 11.03 ? 625 PRO A CD 1 ATOM 4966 N N . PRO A 1 626 ? 58.782 58.062 -25.595 1.00 12.12 ? 626 PRO A N 1 ATOM 4967 C CA . PRO A 1 626 ? 58.024 57.553 -24.416 1.00 11.29 ? 626 PRO A CA 1 ATOM 4968 C C . PRO A 1 626 ? 58.789 57.956 -23.153 1.00 10.51 ? 626 PRO A C 1 ATOM 4969 O O . PRO A 1 626 ? 60.039 57.794 -23.046 1.00 12.27 ? 626 PRO A O 1 ATOM 4970 C CB . PRO A 1 626 ? 58.067 56.024 -24.589 1.00 11.01 ? 626 PRO A CB 1 ATOM 4971 C CG . PRO A 1 626 ? 58.476 55.792 -26.087 1.00 11.75 ? 626 PRO A CG 1 ATOM 4972 C CD . PRO A 1 626 ? 59.448 56.952 -26.286 1.00 12.80 ? 626 PRO A CD 1 ATOM 4973 N N . MET A 1 627 ? 58.087 58.519 -22.169 1.00 11.58 ? 627 MET A N 1 ATOM 4974 C CA . MET A 1 627 ? 58.695 58.913 -20.869 1.00 8.98 ? 627 MET A CA 1 ATOM 4975 C C . MET A 1 627 ? 59.977 59.680 -21.076 1.00 9.66 ? 627 MET A C 1 ATOM 4976 O O . MET A 1 627 ? 61.003 59.508 -20.350 1.00 10.21 ? 627 MET A O 1 ATOM 4977 C CB . MET A 1 627 ? 59.011 57.640 -20.042 1.00 10.15 ? 627 MET A CB 1 ATOM 4978 C CG . MET A 1 627 ? 57.706 56.959 -19.618 1.00 10.95 ? 627 MET A CG 1 ATOM 4979 S SD . MET A 1 627 ? 57.938 55.294 -18.905 1.00 13.70 ? 627 MET A SD 1 ATOM 4980 C CE . MET A 1 627 ? 58.628 55.651 -17.421 1.00 13.76 ? 627 MET A CE 1 ATOM 4981 N N . GLY A 1 628 ? 59.896 60.575 -22.066 1.00 8.25 ? 628 GLY A N 1 ATOM 4982 C CA . GLY A 1 628 ? 61.102 61.314 -22.442 1.00 9.19 ? 628 GLY A CA 1 ATOM 4983 C C . GLY A 1 628 ? 60.998 62.788 -22.716 1.00 9.28 ? 628 GLY A C 1 ATOM 4984 O O . GLY A 1 628 ? 59.978 63.394 -22.424 1.00 11.92 ? 628 GLY A O 1 ATOM 4985 N N . LEU A 1 629 ? 62.037 63.340 -23.359 1.00 11.25 ? 629 LEU A N 1 ATOM 4986 C CA . LEU A 1 629 ? 62.192 64.797 -23.608 1.00 11.44 ? 629 LEU A CA 1 ATOM 4987 C C . LEU A 1 629 ? 62.586 65.080 -25.054 1.00 12.23 ? 629 LEU A C 1 ATOM 4988 O O . LEU A 1 629 ? 63.270 64.245 -25.696 1.00 11.11 ? 629 LEU A O 1 ATOM 4989 C CB . LEU A 1 629 ? 63.298 65.301 -22.721 1.00 10.57 ? 629 LEU A CB 1 ATOM 4990 C CG . LEU A 1 629 ? 63.036 65.214 -21.197 1.00 8.30 ? 629 LEU A CG 1 ATOM 4991 C CD1 . LEU A 1 629 ? 64.363 65.444 -20.403 1.00 10.39 ? 629 LEU A CD1 1 ATOM 4992 C CD2 . LEU A 1 629 ? 61.899 66.212 -20.869 1.00 11.83 ? 629 LEU A CD2 1 ATOM 4993 N N . ALA A 1 630 ? 62.128 66.232 -25.557 1.00 10.84 ? 630 ALA A N 1 ATOM 4994 C CA . ALA A 1 630 ? 62.508 66.651 -26.923 1.00 12.37 ? 630 ALA A CA 1 ATOM 4995 C C . ALA A 1 630 ? 62.769 68.180 -26.850 1.00 11.16 ? 630 ALA A C 1 ATOM 4996 O O . ALA A 1 630 ? 61.986 68.938 -26.288 1.00 11.99 ? 630 ALA A O 1 ATOM 4997 C CB . ALA A 1 630 ? 61.412 66.371 -27.935 1.00 11.67 ? 630 ALA A CB 1 ATOM 4998 N N . THR A 1 631 ? 63.865 68.633 -27.481 1.00 10.96 ? 631 THR A N 1 ATOM 4999 C CA . THR A 1 631 ? 64.277 70.021 -27.489 1.00 13.69 ? 631 THR A CA 1 ATOM 5000 C C . THR A 1 631 ? 64.001 70.673 -28.836 1.00 11.96 ? 631 THR A C 1 ATOM 5001 O O . THR A 1 631 ? 64.263 70.056 -29.896 1.00 12.07 ? 631 THR A O 1 ATOM 5002 C CB . THR A 1 631 ? 65.788 70.086 -27.216 1.00 14.10 ? 631 THR A CB 1 ATOM 5003 O OG1 . THR A 1 631 ? 66.041 69.437 -25.966 1.00 14.76 ? 631 THR A OG1 1 ATOM 5004 C CG2 . THR A 1 631 ? 66.250 71.521 -27.135 1.00 14.24 ? 631 THR A CG2 1 ATOM 5005 N N . TYR A 1 632 ? 63.427 71.880 -28.776 1.00 10.36 ? 632 TYR A N 1 ATOM 5006 C CA . TYR A 1 632 ? 63.165 72.618 -30.023 1.00 12.41 ? 632 TYR A CA 1 ATOM 5007 C C . TYR A 1 632 ? 63.722 74.023 -29.836 1.00 10.92 ? 632 TYR A C 1 ATOM 5008 O O . TYR A 1 632 ? 64.026 74.453 -28.742 1.00 12.21 ? 632 TYR A O 1 ATOM 5009 C CB . TYR A 1 632 ? 61.670 72.731 -30.373 1.00 12.00 ? 632 TYR A CB 1 ATOM 5010 C CG . TYR A 1 632 ? 61.040 71.416 -30.791 1.00 12.14 ? 632 TYR A CG 1 ATOM 5011 C CD1 . TYR A 1 632 ? 60.660 70.482 -29.819 1.00 14.68 ? 632 TYR A CD1 1 ATOM 5012 C CD2 . TYR A 1 632 ? 60.839 71.081 -32.122 1.00 13.26 ? 632 TYR A CD2 1 ATOM 5013 C CE1 . TYR A 1 632 ? 60.124 69.268 -30.153 1.00 11.73 ? 632 TYR A CE1 1 ATOM 5014 C CE2 . TYR A 1 632 ? 60.268 69.856 -32.489 1.00 12.76 ? 632 TYR A CE2 1 ATOM 5015 C CZ . TYR A 1 632 ? 59.917 68.925 -31.482 1.00 13.83 ? 632 TYR A CZ 1 ATOM 5016 O OH . TYR A 1 632 ? 59.425 67.701 -31.792 1.00 16.31 ? 632 TYR A OH 1 ATOM 5017 N N . VAL A 1 633 ? 63.904 74.744 -30.966 1.00 11.61 ? 633 VAL A N 1 ATOM 5018 C CA . VAL A 1 633 ? 64.439 76.120 -30.915 1.00 11.67 ? 633 VAL A CA 1 ATOM 5019 C C . VAL A 1 633 ? 63.510 77.152 -31.618 1.00 10.26 ? 633 VAL A C 1 ATOM 5020 O O . VAL A 1 633 ? 63.013 76.824 -32.698 1.00 11.78 ? 633 VAL A O 1 ATOM 5021 C CB . VAL A 1 633 ? 65.802 76.159 -31.622 1.00 12.33 ? 633 VAL A CB 1 ATOM 5022 C CG1 . VAL A 1 633 ? 66.372 77.516 -31.630 1.00 12.44 ? 633 VAL A CG1 1 ATOM 5023 C CG2 . VAL A 1 633 ? 66.764 75.167 -30.973 1.00 12.66 ? 633 VAL A CG2 1 ATOM 5024 N N . LEU A 1 634 ? 63.234 78.282 -30.976 1.00 12.29 ? 634 LEU A N 1 ATOM 5025 C CA . LEU A 1 634 ? 62.391 79.366 -31.560 1.00 13.25 ? 634 LEU A CA 1 ATOM 5026 C C . LEU A 1 634 ? 63.371 80.458 -31.947 1.00 13.07 ? 634 LEU A C 1 ATOM 5027 O O . LEU A 1 634 ? 64.154 80.921 -31.086 1.00 13.65 ? 634 LEU A O 1 ATOM 5028 C CB . LEU A 1 634 ? 61.411 79.927 -30.505 1.00 13.45 ? 634 LEU A CB 1 ATOM 5029 C CG . LEU A 1 634 ? 60.470 78.870 -29.845 1.00 18.76 ? 634 LEU A CG 1 ATOM 5030 C CD1 . LEU A 1 634 ? 59.253 79.618 -29.352 1.00 19.66 ? 634 LEU A CD1 1 ATOM 5031 C CD2 . LEU A 1 634 ? 60.065 77.730 -30.766 1.00 18.63 ? 634 LEU A CD2 1 ATOM 5032 N N . THR A 1 635 ? 63.350 80.850 -33.242 1.00 13.72 ? 635 THR A N 1 ATOM 5033 C CA . THR A 1 635 ? 64.300 81.840 -33.763 1.00 14.12 ? 635 THR A CA 1 ATOM 5034 C C . THR A 1 635 ? 63.537 83.015 -34.401 1.00 14.58 ? 635 THR A C 1 ATOM 5035 O O . THR A 1 635 ? 62.589 82.789 -35.160 1.00 16.27 ? 635 THR A O 1 ATOM 5036 C CB . THR A 1 635 ? 65.176 81.162 -34.809 1.00 13.80 ? 635 THR A CB 1 ATOM 5037 O OG1 . THR A 1 635 ? 65.850 80.017 -34.235 1.00 14.55 ? 635 THR A OG1 1 ATOM 5038 C CG2 . THR A 1 635 ? 66.217 82.127 -35.326 1.00 15.20 ? 635 THR A CG2 1 ATOM 5039 N N . ILE A 1 636 ? 63.967 84.242 -34.106 1.00 15.81 ? 636 ILE A N 1 ATOM 5040 C CA . ILE A 1 636 ? 63.247 85.370 -34.678 1.00 17.67 ? 636 ILE A CA 1 ATOM 5041 C C . ILE A 1 636 ? 63.832 85.766 -36.021 1.00 19.85 ? 636 ILE A C 1 ATOM 5042 O O . ILE A 1 636 ? 64.940 85.410 -36.328 1.00 18.84 ? 636 ILE A O 1 ATOM 5043 C CB . ILE A 1 636 ? 63.272 86.564 -33.743 1.00 18.06 ? 636 ILE A CB 1 ATOM 5044 C CG1 . ILE A 1 636 ? 62.235 87.595 -34.190 1.00 19.73 ? 636 ILE A CG1 1 ATOM 5045 C CG2 . ILE A 1 636 ? 64.684 87.206 -33.738 1.00 18.89 ? 636 ILE A CG2 1 ATOM 5046 C CD1 . ILE A 1 636 ? 62.230 88.847 -33.352 1.00 18.79 ? 636 ILE A CD1 1 ATOM 5047 N N . SER A 1 637 ? 63.031 86.448 -36.833 1.00 22.31 ? 637 SER A N 1 ATOM 5048 C CA . SER A 1 637 ? 63.490 86.932 -38.144 1.00 25.33 ? 637 SER A CA 1 ATOM 5049 C C . SER A 1 637 ? 62.854 88.295 -38.385 1.00 27.18 ? 637 SER A C 1 ATOM 5050 O O . SER A 1 637 ? 62.067 88.782 -37.587 1.00 25.15 ? 637 SER A O 1 ATOM 5051 C CB . SER A 1 637 ? 63.128 85.962 -39.267 1.00 26.31 ? 637 SER A CB 1 ATOM 5052 O OG . SER A 1 637 ? 61.743 85.728 -39.244 1.00 30.60 ? 637 SER A OG 1 ATOM 5053 N N . ASP A 1 638 ? 63.224 88.950 -39.478 1.00 29.64 ? 638 ASP A N 1 ATOM 5054 C CA . ASP A 1 638 ? 62.674 90.273 -39.730 1.00 31.95 ? 638 ASP A CA 1 ATOM 5055 C C . ASP A 1 638 ? 61.319 90.234 -40.465 1.00 31.99 ? 638 ASP A C 1 ATOM 5056 O O . ASP A 1 638 ? 60.529 91.185 -40.372 1.00 33.42 ? 638 ASP A O 1 ATOM 5057 C CB . ASP A 1 638 ? 63.700 91.063 -40.531 1.00 35.07 ? 638 ASP A CB 1 ATOM 5058 C CG . ASP A 1 638 ? 64.117 90.316 -41.768 1.00 37.77 ? 638 ASP A CG 1 ATOM 5059 O OD1 . ASP A 1 638 ? 63.252 90.149 -42.664 1.00 40.12 ? 638 ASP A OD1 1 ATOM 5060 O OD2 . ASP A 1 638 ? 65.283 89.863 -41.837 1.00 40.79 ? 638 ASP A OD2 1 ATOM 5061 N N . SER A 1 639 ? 61.036 89.139 -41.165 1.00 30.80 ? 639 SER A N 1 ATOM 5062 C CA . SER A 1 639 ? 59.785 89.042 -41.900 1.00 30.49 ? 639 SER A CA 1 ATOM 5063 C C . SER A 1 639 ? 59.178 87.630 -41.811 1.00 30.66 ? 639 SER A C 1 ATOM 5064 O O . SER A 1 639 ? 59.737 86.764 -41.136 1.00 29.36 ? 639 SER A O 1 ATOM 5065 C CB . SER A 1 639 ? 60.059 89.446 -43.357 1.00 30.02 ? 639 SER A CB 1 ATOM 5066 O OG . SER A 1 639 ? 61.130 88.676 -43.887 1.00 31.09 ? 639 SER A OG 1 ATOM 5067 N N . LYS A 1 640 ? 58.041 87.387 -42.473 1.00 30.21 ? 640 LYS A N 1 ATOM 5068 C CA . LYS A 1 640 ? 57.435 86.056 -42.418 1.00 29.63 ? 640 LYS A CA 1 ATOM 5069 C C . LYS A 1 640 ? 58.429 84.954 -42.715 1.00 28.76 ? 640 LYS A C 1 ATOM 5070 O O . LYS A 1 640 ? 59.153 84.992 -43.705 1.00 28.77 ? 640 LYS A O 1 ATOM 5071 C CB . LYS A 1 640 ? 56.250 85.919 -43.374 1.00 30.60 ? 640 LYS A CB 1 ATOM 5072 C CG . LYS A 1 640 ? 55.039 86.741 -42.960 1.00 33.53 ? 640 LYS A CG 1 ATOM 5073 C CD . LYS A 1 640 ? 53.806 86.455 -43.831 1.00 33.87 ? 640 LYS A CD 1 ATOM 5074 C CE . LYS A 1 640 ? 52.710 87.491 -43.535 1.00 36.14 ? 640 LYS A CE 1 ATOM 5075 N NZ . LYS A 1 640 ? 51.328 87.016 -43.888 1.00 38.09 ? 640 LYS A NZ 1 ATOM 5076 N N . PRO A 1 641 ? 58.514 83.963 -41.822 1.00 27.42 ? 641 PRO A N 1 ATOM 5077 C CA . PRO A 1 641 ? 59.443 82.845 -42.038 1.00 25.29 ? 641 PRO A CA 1 ATOM 5078 C C . PRO A 1 641 ? 58.788 81.855 -42.993 1.00 23.50 ? 641 PRO A C 1 ATOM 5079 O O . PRO A 1 641 ? 57.561 81.767 -43.054 1.00 23.16 ? 641 PRO A O 1 ATOM 5080 C CB . PRO A 1 641 ? 59.588 82.238 -40.633 1.00 27.01 ? 641 PRO A CB 1 ATOM 5081 C CG . PRO A 1 641 ? 59.252 83.376 -39.735 1.00 28.04 ? 641 PRO A CG 1 ATOM 5082 C CD . PRO A 1 641 ? 58.073 84.002 -40.426 1.00 27.28 ? 641 PRO A CD 1 ATOM 5083 N N . GLU A 1 642 ? 59.584 81.090 -43.712 1.00 23.03 ? 642 GLU A N 1 ATOM 5084 C CA . GLU A 1 642 ? 59.031 80.109 -44.665 1.00 23.29 ? 642 GLU A CA 1 ATOM 5085 C C . GLU A 1 642 ? 58.079 79.051 -44.094 1.00 23.73 ? 642 GLU A C 1 ATOM 5086 O O . GLU A 1 642 ? 57.057 78.716 -44.690 1.00 23.96 ? 642 GLU A O 1 ATOM 5087 C CB . GLU A 1 642 ? 60.169 79.379 -45.364 1.00 26.51 ? 642 GLU A CB 1 ATOM 5088 C CG . GLU A 1 642 ? 59.675 78.398 -46.400 1.00 30.28 ? 642 GLU A CG 1 ATOM 5089 C CD . GLU A 1 642 ? 60.790 77.616 -47.090 1.00 33.24 ? 642 GLU A CD 1 ATOM 5090 O OE1 . GLU A 1 642 ? 61.975 78.057 -47.045 1.00 34.71 ? 642 GLU A OE1 1 ATOM 5091 O OE2 . GLU A 1 642 ? 60.452 76.550 -47.681 1.00 35.81 ? 642 GLU A OE2 1 ATOM 5092 N N . HIS A 1 643 ? 58.404 78.550 -42.909 1.00 22.74 ? 643 HIS A N 1 ATOM 5093 C CA . HIS A 1 643 ? 57.623 77.478 -42.296 1.00 22.08 ? 643 HIS A CA 1 ATOM 5094 C C . HIS A 1 643 ? 56.629 77.872 -41.222 1.00 21.40 ? 643 HIS A C 1 ATOM 5095 O O . HIS A 1 643 ? 56.165 77.006 -40.457 1.00 19.75 ? 643 HIS A O 1 ATOM 5096 C CB . HIS A 1 643 ? 58.585 76.401 -41.781 1.00 22.56 ? 643 HIS A CB 1 ATOM 5097 C CG . HIS A 1 643 ? 59.437 75.813 -42.857 1.00 22.71 ? 643 HIS A CG 1 ATOM 5098 N ND1 . HIS A 1 643 ? 58.989 74.806 -43.680 1.00 22.21 ? 643 HIS A ND1 1 ATOM 5099 C CD2 . HIS A 1 643 ? 60.687 76.122 -43.282 1.00 22.66 ? 643 HIS A CD2 1 ATOM 5100 C CE1 . HIS A 1 643 ? 59.927 74.514 -44.564 1.00 23.68 ? 643 HIS A CE1 1 ATOM 5101 N NE2 . HIS A 1 643 ? 60.967 75.296 -44.341 1.00 22.03 ? 643 HIS A NE2 1 ATOM 5102 N N . THR A 1 644 ? 56.295 79.152 -41.184 1.00 18.14 ? 644 THR A N 1 ATOM 5103 C CA . THR A 1 644 ? 55.316 79.676 -40.249 1.00 17.37 ? 644 THR A CA 1 ATOM 5104 C C . THR A 1 644 ? 54.141 80.319 -40.950 1.00 19.23 ? 644 THR A C 1 ATOM 5105 O O . THR A 1 644 ? 54.316 81.186 -41.814 1.00 19.76 ? 644 THR A O 1 ATOM 5106 C CB . THR A 1 644 ? 55.925 80.646 -39.281 1.00 17.27 ? 644 THR A CB 1 ATOM 5107 O OG1 . THR A 1 644 ? 56.904 79.918 -38.539 1.00 16.78 ? 644 THR A OG1 1 ATOM 5108 C CG2 . THR A 1 644 ? 54.864 81.188 -38.320 1.00 17.47 ? 644 THR A CG2 1 ATOM 5109 N N . SER A 1 645 ? 52.940 79.895 -40.586 1.00 17.01 ? 645 SER A N 1 ATOM 5110 C CA . SER A 1 645 ? 51.736 80.450 -41.203 1.00 17.84 ? 645 SER A CA 1 ATOM 5111 C C . SER A 1 645 ? 51.043 81.327 -40.182 1.00 18.66 ? 645 SER A C 1 ATOM 5112 O O . SER A 1 645 ? 51.369 81.308 -38.983 1.00 18.00 ? 645 SER A O 1 ATOM 5113 C CB . SER A 1 645 ? 50.790 79.348 -41.676 1.00 18.73 ? 645 SER A CB 1 ATOM 5114 O OG . SER A 1 645 ? 50.329 78.559 -40.577 1.00 17.36 ? 645 SER A OG 1 ATOM 5115 N N . TYR A 1 646 ? 50.092 82.130 -40.666 1.00 17.40 ? 646 TYR A N 1 ATOM 5116 C CA . TYR A 1 646 ? 49.350 83.031 -39.803 1.00 16.45 ? 646 TYR A CA 1 ATOM 5117 C C . TYR A 1 646 ? 47.858 82.766 -39.860 1.00 16.66 ? 646 TYR A C 1 ATOM 5118 O O . TYR A 1 646 ? 47.296 82.500 -40.924 1.00 18.41 ? 646 TYR A O 1 ATOM 5119 C CB . TYR A 1 646 ? 49.671 84.490 -40.156 1.00 18.09 ? 646 TYR A CB 1 ATOM 5120 C CG . TYR A 1 646 ? 51.129 84.776 -39.923 1.00 17.11 ? 646 TYR A CG 1 ATOM 5121 C CD1 . TYR A 1 646 ? 52.060 84.463 -40.893 1.00 17.58 ? 646 TYR A CD1 1 ATOM 5122 C CD2 . TYR A 1 646 ? 51.580 85.207 -38.674 1.00 16.77 ? 646 TYR A CD2 1 ATOM 5123 C CE1 . TYR A 1 646 ? 53.429 84.555 -40.637 1.00 19.93 ? 646 TYR A CE1 1 ATOM 5124 C CE2 . TYR A 1 646 ? 52.968 85.295 -38.381 1.00 18.00 ? 646 TYR A CE2 1 ATOM 5125 C CZ . TYR A 1 646 ? 53.875 84.965 -39.371 1.00 20.18 ? 646 TYR A CZ 1 ATOM 5126 O OH . TYR A 1 646 ? 55.239 85.012 -39.098 1.00 19.68 ? 646 TYR A OH 1 ATOM 5127 N N . ALA A 1 647 ? 47.220 82.776 -38.682 1.00 15.79 ? 647 ALA A N 1 ATOM 5128 C CA . ALA A 1 647 ? 45.805 82.498 -38.642 1.00 16.23 ? 647 ALA A CA 1 ATOM 5129 C C . ALA A 1 647 ? 44.996 83.693 -39.104 1.00 14.81 ? 647 ALA A C 1 ATOM 5130 O O . ALA A 1 647 ? 45.411 84.807 -38.946 1.00 16.94 ? 647 ALA A O 1 ATOM 5131 C CB . ALA A 1 647 ? 45.397 82.189 -37.212 1.00 15.12 ? 647 ALA A CB 1 ATOM 5132 N N . SER A 1 648 ? 43.850 83.433 -39.708 1.00 16.02 ? 648 SER A N 1 ATOM 5133 C CA . SER A 1 648 ? 42.965 84.550 -40.016 1.00 16.53 ? 648 SER A CA 1 ATOM 5134 C C . SER A 1 648 ? 42.027 84.678 -38.807 1.00 16.17 ? 648 SER A C 1 ATOM 5135 O O . SER A 1 648 ? 41.799 83.670 -38.077 1.00 17.41 ? 648 SER A O 1 ATOM 5136 C CB . SER A 1 648 ? 42.121 84.285 -41.269 1.00 17.28 ? 648 SER A CB 1 ATOM 5137 O OG . SER A 1 648 ? 41.440 83.052 -41.173 1.00 23.47 ? 648 SER A OG 1 ATOM 5138 N N . ASN A 1 649 ? 41.504 85.872 -38.575 1.00 14.75 ? 649 ASN A N 1 ATOM 5139 C CA . ASN A 1 649 ? 40.586 86.164 -37.472 1.00 14.70 ? 649 ASN A CA 1 ATOM 5140 C C . ASN A 1 649 ? 39.351 86.923 -37.964 1.00 15.44 ? 649 ASN A C 1 ATOM 5141 O O . ASN A 1 649 ? 39.480 87.888 -38.731 1.00 14.89 ? 649 ASN A O 1 ATOM 5142 C CB . ASN A 1 649 ? 41.287 86.973 -36.418 1.00 15.62 ? 649 ASN A CB 1 ATOM 5143 C CG . ASN A 1 649 ? 42.470 86.217 -35.795 1.00 17.66 ? 649 ASN A CG 1 ATOM 5144 O OD1 . ASN A 1 649 ? 42.303 85.255 -35.006 1.00 17.80 ? 649 ASN A OD1 1 ATOM 5145 N ND2 . ASN A 1 649 ? 43.666 86.651 -36.153 1.00 17.25 ? 649 ASN A ND2 1 ATOM 5146 N N . LEU A 1 650 ? 38.187 86.505 -37.484 1.00 14.64 ? 650 LEU A N 1 ATOM 5147 C CA . LEU A 1 650 ? 36.880 87.084 -37.837 1.00 16.18 ? 650 LEU A CA 1 ATOM 5148 C C . LEU A 1 650 ? 36.066 87.359 -36.560 1.00 18.13 ? 650 LEU A C 1 ATOM 5149 O O . LEU A 1 650 ? 35.796 86.438 -35.739 1.00 19.55 ? 650 LEU A O 1 ATOM 5150 C CB . LEU A 1 650 ? 36.130 86.104 -38.790 1.00 15.07 ? 650 LEU A CB 1 ATOM 5151 C CG . LEU A 1 650 ? 34.676 86.434 -39.165 1.00 15.73 ? 650 LEU A CG 1 ATOM 5152 C CD1 . LEU A 1 650 ? 34.624 87.726 -40.064 1.00 14.22 ? 650 LEU A CD1 1 ATOM 5153 C CD2 . LEU A 1 650 ? 34.084 85.298 -39.907 1.00 15.78 ? 650 LEU A CD2 1 ATOM 5154 N N . LEU A 1 651 ? 35.727 88.625 -36.335 1.00 18.22 ? 651 LEU A N 1 ATOM 5155 C CA . LEU A 1 651 ? 34.911 89.009 -35.205 1.00 18.73 ? 651 LEU A CA 1 ATOM 5156 C C . LEU A 1 651 ? 33.466 89.221 -35.676 1.00 19.24 ? 651 LEU A C 1 ATOM 5157 O O . LEU A 1 651 ? 33.188 90.086 -36.523 1.00 20.35 ? 651 LEU A O 1 ATOM 5158 C CB . LEU A 1 651 ? 35.454 90.274 -34.557 1.00 20.90 ? 651 LEU A CB 1 ATOM 5159 C CG . LEU A 1 651 ? 35.171 90.613 -33.074 1.00 22.78 ? 651 LEU A CG 1 ATOM 5160 C CD1 . LEU A 1 651 ? 33.814 91.192 -32.883 1.00 25.77 ? 651 LEU A CD1 1 ATOM 5161 C CD2 . LEU A 1 651 ? 35.322 89.364 -32.210 1.00 23.08 ? 651 LEU A CD2 1 ATOM 5162 N N . LEU A 1 652 ? 32.552 88.386 -35.173 1.00 18.80 ? 652 LEU A N 1 ATOM 5163 C CA . LEU A 1 652 ? 31.156 88.481 -35.570 1.00 18.25 ? 652 LEU A CA 1 ATOM 5164 C C . LEU A 1 652 ? 30.348 89.160 -34.460 1.00 20.54 ? 652 LEU A C 1 ATOM 5165 O O . LEU A 1 652 ? 30.224 88.648 -33.340 1.00 17.60 ? 652 LEU A O 1 ATOM 5166 C CB . LEU A 1 652 ? 30.614 87.088 -35.865 1.00 17.69 ? 652 LEU A CB 1 ATOM 5167 C CG . LEU A 1 652 ? 31.362 86.356 -36.986 1.00 17.95 ? 652 LEU A CG 1 ATOM 5168 C CD1 . LEU A 1 652 ? 30.782 84.942 -37.137 1.00 17.41 ? 652 LEU A CD1 1 ATOM 5169 C CD2 . LEU A 1 652 ? 31.265 87.126 -38.353 1.00 20.10 ? 652 LEU A CD2 1 ATOM 5170 N N . ARG A 1 653 ? 29.826 90.349 -34.770 1.00 19.89 ? 653 ARG A N 1 ATOM 5171 C CA . ARG A 1 653 ? 29.021 91.088 -33.823 1.00 21.60 ? 653 ARG A CA 1 ATOM 5172 C C . ARG A 1 653 ? 28.439 92.275 -34.552 1.00 23.20 ? 653 ARG A C 1 ATOM 5173 O O . ARG A 1 653 ? 29.066 92.794 -35.504 1.00 20.47 ? 653 ARG A O 1 ATOM 5174 C CB . ARG A 1 653 ? 29.893 91.588 -32.696 1.00 22.30 ? 653 ARG A CB 1 ATOM 5175 C CG . ARG A 1 653 ? 30.955 92.553 -33.185 1.00 27.53 ? 653 ARG A CG 1 ATOM 5176 C CD . ARG A 1 653 ? 31.519 93.348 -32.046 1.00 28.82 ? 653 ARG A CD 1 ATOM 5177 N NE . ARG A 1 653 ? 30.434 93.781 -31.185 1.00 34.50 ? 653 ARG A NE 1 ATOM 5178 C CZ . ARG A 1 653 ? 30.597 94.471 -30.066 1.00 35.83 ? 653 ARG A CZ 1 ATOM 5179 N NH1 . ARG A 1 653 ? 31.812 94.831 -29.677 1.00 37.82 ? 653 ARG A NH1 1 ATOM 5180 N NH2 . ARG A 1 653 ? 29.552 94.731 -29.299 1.00 38.36 ? 653 ARG A NH2 1 ATOM 5181 N N . LYS A 1 654 ? 27.270 92.741 -34.134 1.00 24.16 ? 654 LYS A N 1 ATOM 5182 C CA . LYS A 1 654 ? 26.757 93.933 -34.805 1.00 27.57 ? 654 LYS A CA 1 ATOM 5183 C C . LYS A 1 654 ? 27.549 95.132 -34.232 1.00 28.38 ? 654 LYS A C 1 ATOM 5184 O O . LYS A 1 654 ? 28.117 95.056 -33.123 1.00 29.96 ? 654 LYS A O 1 ATOM 5185 C CB . LYS A 1 654 ? 25.248 94.070 -34.594 1.00 29.22 ? 654 LYS A CB 1 ATOM 5186 C CG . LYS A 1 654 ? 24.410 93.118 -35.469 1.00 30.19 ? 654 LYS A CG 1 ATOM 5187 C CD . LYS A 1 654 ? 23.122 93.801 -35.909 1.00 32.89 ? 654 LYS A CD 1 ATOM 5188 C CE . LYS A 1 654 ? 21.990 92.811 -36.287 1.00 34.16 ? 654 LYS A CE 1 ATOM 5189 N NZ . LYS A 1 654 ? 22.352 91.955 -37.473 1.00 36.26 ? 654 LYS A NZ 1 ATOM 5190 N N . ASN A 1 655 ? 27.617 96.207 -35.005 1.00 30.70 ? 655 ASN A N 1 ATOM 5191 C CA . ASN A 1 655 ? 28.356 97.402 -34.624 1.00 31.82 ? 655 ASN A CA 1 ATOM 5192 C C . ASN A 1 655 ? 29.767 97.095 -34.111 1.00 31.26 ? 655 ASN A C 1 ATOM 5193 O O . ASN A 1 655 ? 30.109 97.311 -32.950 1.00 31.15 ? 655 ASN A O 1 ATOM 5194 C CB . ASN A 1 655 ? 27.533 98.213 -33.627 1.00 34.68 ? 655 ASN A CB 1 ATOM 5195 C CG . ASN A 1 655 ? 26.269 98.791 -34.282 1.00 37.75 ? 655 ASN A CG 1 ATOM 5196 O OD1 . ASN A 1 655 ? 26.361 99.567 -35.259 1.00 39.50 ? 655 ASN A OD1 1 ATOM 5197 N ND2 . ASN A 1 655 ? 25.081 98.392 -33.779 1.00 38.55 ? 655 ASN A ND2 1 ATOM 5198 N N . PRO A 1 656 ? 30.620 96.590 -35.016 1.00 30.27 ? 656 PRO A N 1 ATOM 5199 C CA . PRO A 1 656 ? 31.993 96.256 -34.652 1.00 29.65 ? 656 PRO A CA 1 ATOM 5200 C C . PRO A 1 656 ? 32.873 97.474 -34.604 1.00 28.75 ? 656 PRO A C 1 ATOM 5201 O O . PRO A 1 656 ? 32.552 98.525 -35.152 1.00 28.59 ? 656 PRO A O 1 ATOM 5202 C CB . PRO A 1 656 ? 32.418 95.291 -35.737 1.00 29.37 ? 656 PRO A CB 1 ATOM 5203 C CG . PRO A 1 656 ? 31.673 95.847 -36.946 1.00 29.44 ? 656 PRO A CG 1 ATOM 5204 C CD . PRO A 1 656 ? 30.315 96.192 -36.404 1.00 29.98 ? 656 PRO A CD 1 ATOM 5205 N N . THR A 1 657 ? 33.985 97.308 -33.922 1.00 28.71 ? 657 THR A N 1 ATOM 5206 C CA . THR A 1 657 ? 34.966 98.355 -33.764 1.00 29.11 ? 657 THR A CA 1 ATOM 5207 C C . THR A 1 657 ? 36.319 97.715 -34.140 1.00 29.12 ? 657 THR A C 1 ATOM 5208 O O . THR A 1 657 ? 36.463 96.499 -34.056 1.00 28.22 ? 657 THR A O 1 ATOM 5209 C CB . THR A 1 657 ? 34.953 98.831 -32.311 1.00 29.82 ? 657 THR A CB 1 ATOM 5210 O OG1 . THR A 1 657 ? 35.431 100.162 -32.272 1.00 34.42 ? 657 THR A OG1 1 ATOM 5211 C CG2 . THR A 1 657 ? 35.839 97.984 -31.443 1.00 31.10 ? 657 THR A CG2 1 ATOM 5212 N N . SER A 1 658 ? 37.293 98.508 -34.570 1.00 28.73 ? 658 SER A N 1 ATOM 5213 C CA . SER A 1 658 ? 38.592 97.977 -34.971 1.00 29.74 ? 658 SER A CA 1 ATOM 5214 C C . SER A 1 658 ? 39.318 97.219 -33.842 1.00 29.66 ? 658 SER A C 1 ATOM 5215 O O . SER A 1 658 ? 39.117 97.496 -32.660 1.00 29.99 ? 658 SER A O 1 ATOM 5216 C CB . SER A 1 658 ? 39.508 99.117 -35.436 1.00 30.36 ? 658 SER A CB 1 ATOM 5217 O OG . SER A 1 658 ? 39.904 99.891 -34.306 1.00 31.94 ? 658 SER A OG 1 ATOM 5218 N N . LEU A 1 659 ? 40.163 96.273 -34.243 1.00 29.62 ? 659 LEU A N 1 ATOM 5219 C CA . LEU A 1 659 ? 40.980 95.491 -33.318 1.00 29.59 ? 659 LEU A CA 1 ATOM 5220 C C . LEU A 1 659 ? 42.368 95.363 -33.956 1.00 28.86 ? 659 LEU A C 1 ATOM 5221 O O . LEU A 1 659 ? 42.642 94.472 -34.760 1.00 28.63 ? 659 LEU A O 1 ATOM 5222 C CB . LEU A 1 659 ? 40.357 94.105 -33.075 1.00 31.81 ? 659 LEU A CB 1 ATOM 5223 C CG . LEU A 1 659 ? 39.241 94.027 -32.022 1.00 32.41 ? 659 LEU A CG 1 ATOM 5224 C CD1 . LEU A 1 659 ? 38.521 92.713 -32.163 1.00 35.15 ? 659 LEU A CD1 1 ATOM 5225 C CD2 . LEU A 1 659 ? 39.807 94.193 -30.630 1.00 34.13 ? 659 LEU A CD2 1 ATOM 5226 N N . PRO A 1 660 ? 43.253 96.306 -33.638 1.00 28.59 ? 660 PRO A N 1 ATOM 5227 C CA . PRO A 1 660 ? 44.612 96.257 -34.199 1.00 28.30 ? 660 PRO A CA 1 ATOM 5228 C C . PRO A 1 660 ? 45.444 95.235 -33.412 1.00 27.03 ? 660 PRO A C 1 ATOM 5229 O O . PRO A 1 660 ? 45.215 95.043 -32.224 1.00 27.56 ? 660 PRO A O 1 ATOM 5230 C CB . PRO A 1 660 ? 45.113 97.684 -34.014 1.00 27.86 ? 660 PRO A CB 1 ATOM 5231 C CG . PRO A 1 660 ? 44.477 98.105 -32.730 1.00 28.25 ? 660 PRO A CG 1 ATOM 5232 C CD . PRO A 1 660 ? 43.075 97.453 -32.737 1.00 29.68 ? 660 PRO A CD 1 ATOM 5233 N N . LEU A 1 661 ? 46.404 94.608 -34.064 1.00 26.54 ? 661 LEU A N 1 ATOM 5234 C CA . LEU A 1 661 ? 47.197 93.578 -33.384 1.00 25.89 ? 661 LEU A CA 1 ATOM 5235 C C . LEU A 1 661 ? 48.712 93.864 -33.427 1.00 25.71 ? 661 LEU A C 1 ATOM 5236 O O . LEU A 1 661 ? 49.497 93.036 -33.918 1.00 26.43 ? 661 LEU A O 1 ATOM 5237 C CB . LEU A 1 661 ? 46.894 92.245 -34.063 1.00 24.80 ? 661 LEU A CB 1 ATOM 5238 C CG . LEU A 1 661 ? 45.410 91.848 -34.099 1.00 24.92 ? 661 LEU A CG 1 ATOM 5239 C CD1 . LEU A 1 661 ? 45.147 90.647 -35.036 1.00 25.11 ? 661 LEU A CD1 1 ATOM 5240 C CD2 . LEU A 1 661 ? 44.989 91.597 -32.681 1.00 25.15 ? 661 LEU A CD2 1 ATOM 5241 N N . GLY A 1 662 ? 49.103 95.047 -32.939 1.00 25.69 ? 662 GLY A N 1 ATOM 5242 C CA . GLY A 1 662 ? 50.509 95.432 -32.981 1.00 25.86 ? 662 GLY A CA 1 ATOM 5243 C C . GLY A 1 662 ? 51.114 95.056 -34.327 1.00 24.05 ? 662 GLY A C 1 ATOM 5244 O O . GLY A 1 662 ? 50.665 95.517 -35.352 1.00 24.68 ? 662 GLY A O 1 ATOM 5245 N N . GLN A 1 663 ? 52.141 94.211 -34.302 1.00 24.97 ? 663 GLN A N 1 ATOM 5246 C CA . GLN A 1 663 ? 52.831 93.729 -35.505 1.00 24.78 ? 663 GLN A CA 1 ATOM 5247 C C . GLN A 1 663 ? 52.188 92.561 -36.273 1.00 25.19 ? 663 GLN A C 1 ATOM 5248 O O . GLN A 1 663 ? 52.701 92.124 -37.295 1.00 24.87 ? 663 GLN A O 1 ATOM 5249 C CB . GLN A 1 663 ? 54.237 93.233 -35.124 1.00 27.36 ? 663 GLN A CB 1 ATOM 5250 C CG . GLN A 1 663 ? 55.291 94.251 -34.655 1.00 28.98 ? 663 GLN A CG 1 ATOM 5251 C CD . GLN A 1 663 ? 56.601 93.534 -34.342 1.00 30.76 ? 663 GLN A CD 1 ATOM 5252 O OE1 . GLN A 1 663 ? 57.259 92.991 -35.251 1.00 33.14 ? 663 GLN A OE1 1 ATOM 5253 N NE2 . GLN A 1 663 ? 56.972 93.495 -33.068 1.00 30.36 ? 663 GLN A NE2 1 ATOM 5254 N N . TYR A 1 664 ? 51.090 92.012 -35.780 1.00 25.36 ? 664 TYR A N 1 ATOM 5255 C CA . TYR A 1 664 ? 50.501 90.853 -36.452 1.00 26.51 ? 664 TYR A CA 1 ATOM 5256 C C . TYR A 1 664 ? 50.261 91.148 -37.914 1.00 28.41 ? 664 TYR A C 1 ATOM 5257 O O . TYR A 1 664 ? 49.687 92.186 -38.230 1.00 29.52 ? 664 TYR A O 1 ATOM 5258 C CB . TYR A 1 664 ? 49.197 90.470 -35.758 1.00 23.12 ? 664 TYR A CB 1 ATOM 5259 C CG . TYR A 1 664 ? 48.703 89.085 -36.107 1.00 20.14 ? 664 TYR A CG 1 ATOM 5260 C CD1 . TYR A 1 664 ? 49.303 87.943 -35.560 1.00 19.30 ? 664 TYR A CD1 1 ATOM 5261 C CD2 . TYR A 1 664 ? 47.612 88.920 -36.974 1.00 18.79 ? 664 TYR A CD2 1 ATOM 5262 C CE1 . TYR A 1 664 ? 48.815 86.678 -35.856 1.00 18.10 ? 664 TYR A CE1 1 ATOM 5263 C CE2 . TYR A 1 664 ? 47.120 87.661 -37.287 1.00 16.30 ? 664 TYR A CE2 1 ATOM 5264 C CZ . TYR A 1 664 ? 47.718 86.523 -36.721 1.00 18.32 ? 664 TYR A CZ 1 ATOM 5265 O OH . TYR A 1 664 ? 47.175 85.268 -37.019 1.00 16.03 ? 664 TYR A OH 1 ATOM 5266 N N . PRO A 1 665 ? 50.662 90.249 -38.824 1.00 29.59 ? 665 PRO A N 1 ATOM 5267 C CA . PRO A 1 665 ? 50.464 90.503 -40.268 1.00 31.38 ? 665 PRO A CA 1 ATOM 5268 C C . PRO A 1 665 ? 49.036 90.721 -40.792 1.00 32.06 ? 665 PRO A C 1 ATOM 5269 O O . PRO A 1 665 ? 48.658 91.843 -41.143 1.00 33.86 ? 665 PRO A O 1 ATOM 5270 C CB . PRO A 1 665 ? 51.117 89.301 -40.952 1.00 31.57 ? 665 PRO A CB 1 ATOM 5271 C CG . PRO A 1 665 ? 51.981 88.658 -39.883 1.00 30.24 ? 665 PRO A CG 1 ATOM 5272 C CD . PRO A 1 665 ? 51.278 88.925 -38.592 1.00 29.98 ? 665 PRO A CD 1 ATOM 5273 N N . GLU A 1 666 ? 48.252 89.648 -40.845 1.00 31.49 ? 666 GLU A N 1 ATOM 5274 C CA . GLU A 1 666 ? 46.887 89.691 -41.357 1.00 31.14 ? 666 GLU A CA 1 ATOM 5275 C C . GLU A 1 666 ? 45.886 90.510 -40.564 1.00 29.66 ? 666 GLU A C 1 ATOM 5276 O O . GLU A 1 666 ? 45.855 90.442 -39.334 1.00 28.62 ? 666 GLU A O 1 ATOM 5277 C CB . GLU A 1 666 ? 46.347 88.275 -41.509 1.00 33.77 ? 666 GLU A CB 1 ATOM 5278 C CG . GLU A 1 666 ? 44.890 88.300 -41.895 1.00 37.41 ? 666 GLU A CG 1 ATOM 5279 C CD . GLU A 1 666 ? 44.561 87.286 -42.959 1.00 38.38 ? 666 GLU A CD 1 ATOM 5280 O OE1 . GLU A 1 666 ? 45.479 86.964 -43.771 1.00 40.24 ? 666 GLU A OE1 1 ATOM 5281 O OE2 . GLU A 1 666 ? 43.387 86.828 -42.994 1.00 39.40 ? 666 GLU A OE2 1 ATOM 5282 N N . ASP A 1 667 ? 45.045 91.276 -41.279 1.00 26.71 ? 667 ASP A N 1 ATOM 5283 C CA . ASP A 1 667 ? 44.042 92.134 -40.627 1.00 25.50 ? 667 ASP A CA 1 ATOM 5284 C C . ASP A 1 667 ? 42.799 91.365 -40.154 1.00 21.52 ? 667 ASP A C 1 ATOM 5285 O O . ASP A 1 667 ? 42.305 90.477 -40.842 1.00 21.38 ? 667 ASP A O 1 ATOM 5286 C CB . ASP A 1 667 ? 43.540 93.239 -41.577 1.00 28.62 ? 667 ASP A CB 1 ATOM 5287 C CG . ASP A 1 667 ? 44.642 94.161 -42.051 1.00 30.89 ? 667 ASP A CG 1 ATOM 5288 O OD1 . ASP A 1 667 ? 45.564 94.450 -41.258 1.00 32.11 ? 667 ASP A OD1 1 ATOM 5289 O OD2 . ASP A 1 667 ? 44.566 94.610 -43.211 1.00 33.02 ? 667 ASP A OD2 1 ATOM 5290 N N . VAL A 1 668 ? 42.284 91.739 -39.000 1.00 20.96 ? 668 VAL A N 1 ATOM 5291 C CA . VAL A 1 668 ? 41.089 91.062 -38.497 1.00 19.02 ? 668 VAL A CA 1 ATOM 5292 C C . VAL A 1 668 ? 39.929 91.470 -39.379 1.00 19.22 ? 668 VAL A C 1 ATOM 5293 O O . VAL A 1 668 ? 39.895 92.602 -39.832 1.00 18.54 ? 668 VAL A O 1 ATOM 5294 C CB . VAL A 1 668 ? 40.795 91.496 -37.077 1.00 17.44 ? 668 VAL A CB 1 ATOM 5295 C CG1 . VAL A 1 668 ? 39.461 90.944 -36.596 1.00 17.48 ? 668 VAL A CG1 1 ATOM 5296 C CG2 . VAL A 1 668 ? 41.907 90.908 -36.196 1.00 18.87 ? 668 VAL A CG2 1 ATOM 5297 N N . LYS A 1 669 ? 39.016 90.539 -39.621 1.00 18.37 ? 669 LYS A N 1 ATOM 5298 C CA . LYS A 1 669 ? 37.811 90.806 -40.410 1.00 18.31 ? 669 LYS A CA 1 ATOM 5299 C C . LYS A 1 669 ? 36.615 90.869 -39.486 1.00 18.88 ? 669 LYS A C 1 ATOM 5300 O O . LYS A 1 669 ? 36.649 90.299 -38.368 1.00 17.55 ? 669 LYS A O 1 ATOM 5301 C CB . LYS A 1 669 ? 37.592 89.730 -41.449 1.00 19.28 ? 669 LYS A CB 1 ATOM 5302 C CG . LYS A 1 669 ? 38.401 90.006 -42.695 1.00 25.21 ? 669 LYS A CG 1 ATOM 5303 C CD . LYS A 1 669 ? 37.838 89.253 -43.921 1.00 27.20 ? 669 LYS A CD 1 ATOM 5304 C CE . LYS A 1 669 ? 38.452 89.821 -45.193 1.00 27.50 ? 669 LYS A CE 1 ATOM 5305 N NZ . LYS A 1 669 ? 39.807 90.365 -44.836 1.00 28.46 ? 669 LYS A NZ 1 ATOM 5306 N N . PHE A 1 670 ? 35.564 91.574 -39.922 1.00 17.85 ? 670 PHE A N 1 ATOM 5307 C CA . PHE A 1 670 ? 34.341 91.722 -39.125 1.00 18.08 ? 670 PHE A CA 1 ATOM 5308 C C . PHE A 1 670 ? 33.118 91.302 -39.927 1.00 18.36 ? 670 PHE A C 1 ATOM 5309 O O . PHE A 1 670 ? 33.194 91.172 -41.141 1.00 18.42 ? 670 PHE A O 1 ATOM 5310 C CB . PHE A 1 670 ? 34.182 93.167 -38.655 1.00 18.21 ? 670 PHE A CB 1 ATOM 5311 C CG . PHE A 1 670 ? 35.356 93.650 -37.885 1.00 18.92 ? 670 PHE A CG 1 ATOM 5312 C CD1 . PHE A 1 670 ? 36.507 94.143 -38.539 1.00 20.03 ? 670 PHE A CD1 1 ATOM 5313 C CD2 . PHE A 1 670 ? 35.349 93.543 -36.515 1.00 19.10 ? 670 PHE A CD2 1 ATOM 5314 C CE1 . PHE A 1 670 ? 37.640 94.533 -37.762 1.00 19.54 ? 670 PHE A CE1 1 ATOM 5315 C CE2 . PHE A 1 670 ? 36.459 93.921 -35.737 1.00 19.71 ? 670 PHE A CE2 1 ATOM 5316 C CZ . PHE A 1 670 ? 37.598 94.421 -36.377 1.00 18.72 ? 670 PHE A CZ 1 ATOM 5317 N N . GLY A 1 671 ? 32.016 91.018 -39.230 1.00 19.02 ? 671 GLY A N 1 ATOM 5318 C CA . GLY A 1 671 ? 30.808 90.587 -39.920 1.00 17.13 ? 671 GLY A CA 1 ATOM 5319 C C . GLY A 1 671 ? 29.659 90.499 -38.930 1.00 17.97 ? 671 GLY A C 1 ATOM 5320 O O . GLY A 1 671 ? 29.889 90.481 -37.724 1.00 17.25 ? 671 GLY A O 1 ATOM 5321 N N . ASP A 1 672 ? 28.420 90.505 -39.417 1.00 16.46 ? 672 ASP A N 1 ATOM 5322 C CA . ASP A 1 672 ? 27.312 90.365 -38.482 1.00 17.30 ? 672 ASP A CA 1 ATOM 5323 C C . ASP A 1 672 ? 27.266 88.898 -38.071 1.00 16.13 ? 672 ASP A C 1 ATOM 5324 O O . ASP A 1 672 ? 27.727 88.007 -38.782 1.00 16.25 ? 672 ASP A O 1 ATOM 5325 C CB . ASP A 1 672 ? 25.963 90.643 -39.145 1.00 19.03 ? 672 ASP A CB 1 ATOM 5326 C CG . ASP A 1 672 ? 25.742 92.098 -39.447 1.00 21.11 ? 672 ASP A CG 1 ATOM 5327 O OD1 . ASP A 1 672 ? 26.291 92.990 -38.750 1.00 24.62 ? 672 ASP A OD1 1 ATOM 5328 O OD2 . ASP A 1 672 ? 24.969 92.355 -40.408 1.00 25.61 ? 672 ASP A OD2 1 ATOM 5329 N N . PRO A 1 673 ? 26.648 88.630 -36.922 1.00 17.54 ? 673 PRO A N 1 ATOM 5330 C CA . PRO A 1 673 ? 26.548 87.218 -36.483 1.00 17.22 ? 673 PRO A CA 1 ATOM 5331 C C . PRO A 1 673 ? 25.952 86.327 -37.620 1.00 17.21 ? 673 PRO A C 1 ATOM 5332 O O . PRO A 1 673 ? 25.031 86.731 -38.342 1.00 19.04 ? 673 PRO A O 1 ATOM 5333 C CB . PRO A 1 673 ? 25.588 87.302 -35.310 1.00 17.53 ? 673 PRO A CB 1 ATOM 5334 C CG . PRO A 1 673 ? 25.925 88.641 -34.715 1.00 19.72 ? 673 PRO A CG 1 ATOM 5335 C CD . PRO A 1 673 ? 26.035 89.545 -35.945 1.00 18.35 ? 673 PRO A CD 1 ATOM 5336 N N . ARG A 1 674 ? 26.458 85.121 -37.764 1.00 17.31 ? 674 ARG A N 1 ATOM 5337 C CA . ARG A 1 674 ? 25.990 84.206 -38.789 1.00 18.81 ? 674 ARG A CA 1 ATOM 5338 C C . ARG A 1 674 ? 26.494 82.810 -38.479 1.00 18.74 ? 674 ARG A C 1 ATOM 5339 O O . ARG A 1 674 ? 27.459 82.652 -37.744 1.00 18.00 ? 674 ARG A O 1 ATOM 5340 C CB . ARG A 1 674 ? 26.526 84.622 -40.170 1.00 19.74 ? 674 ARG A CB 1 ATOM 5341 C CG . ARG A 1 674 ? 28.044 84.555 -40.343 1.00 20.49 ? 674 ARG A CG 1 ATOM 5342 C CD . ARG A 1 674 ? 28.420 84.745 -41.810 1.00 22.79 ? 674 ARG A CD 1 ATOM 5343 N NE . ARG A 1 674 ? 29.819 84.427 -42.089 1.00 25.31 ? 674 ARG A NE 1 ATOM 5344 C CZ . ARG A 1 674 ? 30.778 85.333 -42.297 1.00 26.15 ? 674 ARG A CZ 1 ATOM 5345 N NH1 . ARG A 1 674 ? 30.527 86.659 -42.251 1.00 27.37 ? 674 ARG A NH1 1 ATOM 5346 N NH2 . ARG A 1 674 ? 31.997 84.904 -42.623 1.00 26.58 ? 674 ARG A NH2 1 ATOM 5347 N N . GLU A 1 675 ? 25.887 81.798 -39.074 1.00 18.55 ? 675 GLU A N 1 ATOM 5348 C CA . GLU A 1 675 ? 26.357 80.446 -38.825 1.00 18.95 ? 675 GLU A CA 1 ATOM 5349 C C . GLU A 1 675 ? 27.699 80.233 -39.546 1.00 20.43 ? 675 GLU A C 1 ATOM 5350 O O . GLU A 1 675 ? 27.973 80.829 -40.602 1.00 22.55 ? 675 GLU A O 1 ATOM 5351 C CB . GLU A 1 675 ? 25.301 79.450 -39.274 1.00 19.86 ? 675 GLU A CB 1 ATOM 5352 C CG . GLU A 1 675 ? 24.005 79.632 -38.534 1.00 22.36 ? 675 GLU A CG 1 ATOM 5353 C CD . GLU A 1 675 ? 23.202 78.349 -38.454 1.00 26.32 ? 675 GLU A CD 1 ATOM 5354 O OE1 . GLU A 1 675 ? 23.261 77.552 -39.433 1.00 27.54 ? 675 GLU A OE1 1 ATOM 5355 O OE2 . GLU A 1 675 ? 22.505 78.148 -37.417 1.00 27.75 ? 675 GLU A OE2 1 ATOM 5356 N N . ILE A 1 676 ? 28.579 79.427 -38.963 1.00 21.37 ? 676 ILE A N 1 ATOM 5357 C CA . ILE A 1 676 ? 29.883 79.170 -39.567 1.00 21.83 ? 676 ILE A CA 1 ATOM 5358 C C . ILE A 1 676 ? 30.311 77.691 -39.483 1.00 22.01 ? 676 ILE A C 1 ATOM 5359 O O . ILE A 1 676 ? 29.848 76.946 -38.635 1.00 21.20 ? 676 ILE A O 1 ATOM 5360 C CB . ILE A 1 676 ? 30.985 80.021 -38.903 1.00 25.60 ? 676 ILE A CB 1 ATOM 5361 C CG1 . ILE A 1 676 ? 31.376 79.434 -37.565 1.00 25.03 ? 676 ILE A CG1 1 ATOM 5362 C CG2 . ILE A 1 676 ? 30.507 81.448 -38.675 1.00 26.33 ? 676 ILE A CG2 1 ATOM 5363 C CD1 . ILE A 1 676 ? 32.321 80.319 -36.824 1.00 28.45 ? 676 ILE A CD1 1 ATOM 5364 N N . SER A 1 677 ? 31.162 77.263 -40.405 1.00 20.27 ? 677 SER A N 1 ATOM 5365 C CA . SER A 1 677 ? 31.682 75.910 -40.416 1.00 21.55 ? 677 SER A CA 1 ATOM 5366 C C . SER A 1 677 ? 33.191 75.945 -40.520 1.00 20.28 ? 677 SER A C 1 ATOM 5367 O O . SER A 1 677 ? 33.771 76.802 -41.206 1.00 19.32 ? 677 SER A O 1 ATOM 5368 C CB . SER A 1 677 ? 31.095 75.105 -41.587 1.00 23.50 ? 677 SER A CB 1 ATOM 5369 O OG . SER A 1 677 ? 29.804 74.671 -41.200 1.00 28.50 ? 677 SER A OG 1 ATOM 5370 N N . LEU A 1 678 ? 33.822 74.975 -39.859 1.00 20.54 ? 678 LEU A N 1 ATOM 5371 C CA . LEU A 1 678 ? 35.276 74.865 -39.831 1.00 19.18 ? 678 LEU A CA 1 ATOM 5372 C C . LEU A 1 678 ? 35.698 73.442 -39.946 1.00 18.70 ? 678 LEU A C 1 ATOM 5373 O O . LEU A 1 678 ? 35.004 72.550 -39.453 1.00 19.24 ? 678 LEU A O 1 ATOM 5374 C CB . LEU A 1 678 ? 35.821 75.365 -38.487 1.00 18.09 ? 678 LEU A CB 1 ATOM 5375 C CG . LEU A 1 678 ? 35.725 76.848 -38.173 1.00 20.61 ? 678 LEU A CG 1 ATOM 5376 C CD1 . LEU A 1 678 ? 36.194 77.125 -36.754 1.00 20.17 ? 678 LEU A CD1 1 ATOM 5377 C CD2 . LEU A 1 678 ? 36.632 77.606 -39.180 1.00 22.01 ? 678 LEU A CD2 1 ATOM 5378 N N . ARG A 1 679 ? 36.847 73.247 -40.572 1.00 19.69 ? 679 ARG A N 1 ATOM 5379 C CA . ARG A 1 679 ? 37.444 71.944 -40.724 1.00 20.69 ? 679 ARG A CA 1 ATOM 5380 C C . ARG A 1 679 ? 38.960 72.137 -40.660 1.00 21.61 ? 679 ARG A C 1 ATOM 5381 O O . ARG A 1 679 ? 39.529 72.944 -41.391 1.00 20.99 ? 679 ARG A O 1 ATOM 5382 C CB . ARG A 1 679 ? 37.068 71.314 -42.064 1.00 21.02 ? 679 ARG A CB 1 ATOM 5383 C CG . ARG A 1 679 ? 37.416 69.863 -42.127 1.00 24.06 ? 679 ARG A CG 1 ATOM 5384 C CD . ARG A 1 679 ? 37.116 69.265 -43.490 1.00 28.07 ? 679 ARG A CD 1 ATOM 5385 N NE . ARG A 1 679 ? 37.415 67.845 -43.435 1.00 30.90 ? 679 ARG A NE 1 ATOM 5386 C CZ . ARG A 1 679 ? 37.526 67.070 -44.497 1.00 33.40 ? 679 ARG A CZ 1 ATOM 5387 N NH1 . ARG A 1 679 ? 37.363 67.591 -45.717 1.00 34.66 ? 679 ARG A NH1 1 ATOM 5388 N NH2 . ARG A 1 679 ? 37.796 65.779 -44.339 1.00 34.82 ? 679 ARG A NH2 1 ATOM 5389 N N . VAL A 1 680 ? 39.626 71.421 -39.748 1.00 20.20 ? 680 VAL A N 1 ATOM 5390 C CA . VAL A 1 680 ? 41.085 71.484 -39.679 1.00 20.26 ? 680 VAL A CA 1 ATOM 5391 C C . VAL A 1 680 ? 41.568 70.147 -40.182 1.00 22.00 ? 680 VAL A C 1 ATOM 5392 O O . VAL A 1 680 ? 41.049 69.111 -39.745 1.00 22.68 ? 680 VAL A O 1 ATOM 5393 C CB . VAL A 1 680 ? 41.587 71.709 -38.242 1.00 17.91 ? 680 VAL A CB 1 ATOM 5394 C CG1 . VAL A 1 680 ? 43.105 71.621 -38.164 1.00 19.19 ? 680 VAL A CG1 1 ATOM 5395 C CG2 . VAL A 1 680 ? 41.195 73.060 -37.822 1.00 15.03 ? 680 VAL A CG2 1 ATOM 5396 N N . GLY A 1 681 ? 42.543 70.191 -41.107 1.00 23.55 ? 681 GLY A N 1 ATOM 5397 C CA . GLY A 1 681 ? 43.110 68.985 -41.711 1.00 25.86 ? 681 GLY A CA 1 ATOM 5398 C C . GLY A 1 681 ? 42.065 68.060 -42.328 1.00 26.57 ? 681 GLY A C 1 ATOM 5399 O O . GLY A 1 681 ? 41.103 68.529 -42.939 1.00 26.75 ? 681 GLY A O 1 ATOM 5400 N N . ASN A 1 682 ? 42.256 66.749 -42.140 1.00 29.06 ? 682 ASN A N 1 ATOM 5401 C CA . ASN A 1 682 ? 41.350 65.708 -42.636 1.00 30.94 ? 682 ASN A CA 1 ATOM 5402 C C . ASN A 1 682 ? 40.209 65.566 -41.640 1.00 30.75 ? 682 ASN A C 1 ATOM 5403 O O . ASN A 1 682 ? 39.232 64.845 -41.885 1.00 32.40 ? 682 ASN A O 1 ATOM 5404 C CB . ASN A 1 682 ? 42.059 64.353 -42.663 1.00 33.16 ? 682 ASN A CB 1 ATOM 5405 C CG . ASN A 1 682 ? 43.074 64.238 -43.761 1.00 36.26 ? 682 ASN A CG 1 ATOM 5406 O OD1 . ASN A 1 682 ? 42.826 63.579 -44.778 1.00 39.46 ? 682 ASN A OD1 1 ATOM 5407 N ND2 . ASN A 1 682 ? 44.236 64.868 -43.574 1.00 38.23 ? 682 ASN A ND2 1 ATOM 5408 N N . GLY A 1 683 ? 40.358 66.242 -40.514 1.00 29.36 ? 683 GLY A N 1 ATOM 5409 C CA . GLY A 1 683 ? 39.400 66.130 -39.426 1.00 27.98 ? 683 GLY A CA 1 ATOM 5410 C C . GLY A 1 683 ? 37.922 66.348 -39.661 1.00 25.03 ? 683 GLY A C 1 ATOM 5411 O O . GLY A 1 683 ? 37.491 66.543 -40.761 1.00 26.60 ? 683 GLY A O 1 ATOM 5412 N N . PRO A 1 684 ? 37.121 66.297 -38.599 1.00 23.26 ? 684 PRO A N 1 ATOM 5413 C CA . PRO A 1 684 ? 35.677 66.502 -38.683 1.00 21.48 ? 684 PRO A CA 1 ATOM 5414 C C . PRO A 1 684 ? 35.378 67.957 -39.048 1.00 19.97 ? 684 PRO A C 1 ATOM 5415 O O . PRO A 1 684 ? 36.206 68.852 -38.919 1.00 20.28 ? 684 PRO A O 1 ATOM 5416 C CB . PRO A 1 684 ? 35.205 66.175 -37.268 1.00 21.18 ? 684 PRO A CB 1 ATOM 5417 C CG . PRO A 1 684 ? 36.386 66.636 -36.438 1.00 20.81 ? 684 PRO A CG 1 ATOM 5418 C CD . PRO A 1 684 ? 37.527 66.023 -37.205 1.00 22.75 ? 684 PRO A CD 1 ATOM 5419 N N . THR A 1 685 ? 34.178 68.170 -39.544 1.00 19.83 ? 685 THR A N 1 ATOM 5420 C CA . THR A 1 685 ? 33.726 69.493 -39.905 1.00 18.51 ? 685 THR A CA 1 ATOM 5421 C C . THR A 1 685 ? 32.675 69.888 -38.865 1.00 18.02 ? 685 THR A C 1 ATOM 5422 O O . THR A 1 685 ? 31.697 69.180 -38.669 1.00 18.57 ? 685 THR A O 1 ATOM 5423 C CB . THR A 1 685 ? 33.104 69.496 -41.314 1.00 19.63 ? 685 THR A CB 1 ATOM 5424 O OG1 . THR A 1 685 ? 34.128 69.190 -42.266 1.00 20.72 ? 685 THR A OG1 1 ATOM 5425 C CG2 . THR A 1 685 ? 32.520 70.859 -41.590 1.00 19.38 ? 685 THR A CG2 1 ATOM 5426 N N . LEU A 1 686 ? 32.900 71.011 -38.192 1.00 16.63 ? 686 LEU A N 1 ATOM 5427 C CA . LEU A 1 686 ? 31.994 71.456 -37.159 1.00 17.41 ? 686 LEU A CA 1 ATOM 5428 C C . LEU A 1 686 ? 31.210 72.655 -37.617 1.00 17.55 ? 686 LEU A C 1 ATOM 5429 O O . LEU A 1 686 ? 31.767 73.600 -38.193 1.00 17.20 ? 686 LEU A O 1 ATOM 5430 C CB . LEU A 1 686 ? 32.750 71.784 -35.838 1.00 20.33 ? 686 LEU A CB 1 ATOM 5431 C CG . LEU A 1 686 ? 33.751 70.743 -35.289 1.00 21.68 ? 686 LEU A CG 1 ATOM 5432 C CD1 . LEU A 1 686 ? 34.111 71.094 -33.848 1.00 23.66 ? 686 LEU A CD1 1 ATOM 5433 C CD2 . LEU A 1 686 ? 33.202 69.375 -35.365 1.00 22.43 ? 686 LEU A CD2 1 ATOM 5434 N N . ALA A 1 687 ? 29.917 72.623 -37.357 1.00 16.94 ? 687 ALA A N 1 ATOM 5435 C CA . ALA A 1 687 ? 29.061 73.748 -37.722 1.00 17.42 ? 687 ALA A CA 1 ATOM 5436 C C . ALA A 1 687 ? 28.621 74.433 -36.405 1.00 18.27 ? 687 ALA A C 1 ATOM 5437 O O . ALA A 1 687 ? 28.269 73.773 -35.397 1.00 17.60 ? 687 ALA A O 1 ATOM 5438 C CB . ALA A 1 687 ? 27.835 73.256 -38.499 1.00 18.65 ? 687 ALA A CB 1 ATOM 5439 N N . PHE A 1 688 ? 28.596 75.753 -36.432 1.00 16.06 ? 688 PHE A N 1 ATOM 5440 C CA . PHE A 1 688 ? 28.229 76.562 -35.271 1.00 13.96 ? 688 PHE A CA 1 ATOM 5441 C C . PHE A 1 688 ? 27.068 77.517 -35.557 1.00 16.50 ? 688 PHE A C 1 ATOM 5442 O O . PHE A 1 688 ? 26.954 78.060 -36.682 1.00 18.21 ? 688 PHE A O 1 ATOM 5443 C CB . PHE A 1 688 ? 29.410 77.431 -34.830 1.00 14.41 ? 688 PHE A CB 1 ATOM 5444 C CG . PHE A 1 688 ? 30.651 76.641 -34.465 1.00 13.52 ? 688 PHE A CG 1 ATOM 5445 C CD1 . PHE A 1 688 ? 31.483 76.157 -35.458 1.00 13.36 ? 688 PHE A CD1 1 ATOM 5446 C CD2 . PHE A 1 688 ? 30.932 76.341 -33.127 1.00 13.76 ? 688 PHE A CD2 1 ATOM 5447 C CE1 . PHE A 1 688 ? 32.593 75.356 -35.175 1.00 14.56 ? 688 PHE A CE1 1 ATOM 5448 C CE2 . PHE A 1 688 ? 32.062 75.526 -32.803 1.00 13.13 ? 688 PHE A CE2 1 ATOM 5449 C CZ . PHE A 1 688 ? 32.894 75.028 -33.818 1.00 12.82 ? 688 PHE A CZ 1 ATOM 5450 N N . SER A 1 689 ? 26.230 77.732 -34.547 1.00 14.72 ? 689 SER A N 1 ATOM 5451 C CA . SER A 1 689 ? 25.094 78.662 -34.613 1.00 15.80 ? 689 SER A CA 1 ATOM 5452 C C . SER A 1 689 ? 25.629 80.081 -34.668 1.00 15.84 ? 689 SER A C 1 ATOM 5453 O O . SER A 1 689 ? 26.802 80.322 -34.445 1.00 16.02 ? 689 SER A O 1 ATOM 5454 C CB . SER A 1 689 ? 24.180 78.526 -33.370 1.00 16.22 ? 689 SER A CB 1 ATOM 5455 O OG . SER A 1 689 ? 24.717 79.118 -32.189 1.00 16.35 ? 689 SER A OG 1 ATOM 5456 N N . GLU A 1 690 ? 24.755 81.025 -34.996 1.00 17.00 ? 690 GLU A N 1 ATOM 5457 C CA . GLU A 1 690 ? 25.159 82.435 -35.027 1.00 18.11 ? 690 GLU A CA 1 ATOM 5458 C C . GLU A 1 690 ? 25.496 82.908 -33.595 1.00 18.11 ? 690 GLU A C 1 ATOM 5459 O O . GLU A 1 690 ? 26.079 83.973 -33.401 1.00 16.60 ? 690 GLU A O 1 ATOM 5460 C CB . GLU A 1 690 ? 24.034 83.304 -35.668 1.00 21.12 ? 690 GLU A CB 1 ATOM 5461 C CG . GLU A 1 690 ? 22.807 83.623 -34.801 1.00 26.23 ? 690 GLU A CG 1 ATOM 5462 C CD . GLU A 1 690 ? 21.907 84.704 -35.483 1.00 29.45 ? 690 GLU A CD 1 ATOM 5463 O OE1 . GLU A 1 690 ? 21.225 84.365 -36.480 1.00 31.69 ? 690 GLU A OE1 1 ATOM 5464 O OE2 . GLU A 1 690 ? 21.886 85.889 -35.036 1.00 32.34 ? 690 GLU A OE2 1 ATOM 5465 N N . GLN A 1 691 ? 25.162 82.087 -32.584 1.00 17.87 ? 691 GLN A N 1 ATOM 5466 C CA . GLN A 1 691 ? 25.489 82.406 -31.191 1.00 17.30 ? 691 GLN A CA 1 ATOM 5467 C C . GLN A 1 691 ? 26.888 81.824 -30.794 1.00 16.04 ? 691 GLN A C 1 ATOM 5468 O O . GLN A 1 691 ? 27.307 81.990 -29.679 1.00 16.63 ? 691 GLN A O 1 ATOM 5469 C CB . GLN A 1 691 ? 24.435 81.850 -30.230 1.00 20.27 ? 691 GLN A CB 1 ATOM 5470 C CG . GLN A 1 691 ? 23.157 82.686 -30.138 1.00 24.14 ? 691 GLN A CG 1 ATOM 5471 C CD . GLN A 1 691 ? 21.934 81.807 -30.016 1.00 28.79 ? 691 GLN A CD 1 ATOM 5472 O OE1 . GLN A 1 691 ? 21.900 80.841 -29.248 1.00 29.16 ? 691 GLN A OE1 1 ATOM 5473 N NE2 . GLN A 1 691 ? 20.915 82.122 -30.812 1.00 32.46 ? 691 GLN A NE2 1 ATOM 5474 N N . GLY A 1 692 ? 27.546 81.129 -31.706 1.00 13.31 ? 692 GLY A N 1 ATOM 5475 C CA . GLY A 1 692 ? 28.902 80.628 -31.495 1.00 14.39 ? 692 GLY A CA 1 ATOM 5476 C C . GLY A 1 692 ? 28.967 79.278 -30.823 1.00 13.94 ? 692 GLY A C 1 ATOM 5477 O O . GLY A 1 692 ? 30.020 78.860 -30.392 1.00 15.58 ? 692 GLY A O 1 ATOM 5478 N N . LEU A 1 693 ? 27.837 78.606 -30.760 1.00 14.43 ? 693 LEU A N 1 ATOM 5479 C CA . LEU A 1 693 ? 27.744 77.290 -30.123 1.00 14.71 ? 693 LEU A CA 1 ATOM 5480 C C . LEU A 1 693 ? 27.624 76.191 -31.160 1.00 16.01 ? 693 LEU A C 1 ATOM 5481 O O . LEU A 1 693 ? 26.970 76.340 -32.224 1.00 13.89 ? 693 LEU A O 1 ATOM 5482 C CB . LEU A 1 693 ? 26.516 77.265 -29.221 1.00 15.45 ? 693 LEU A CB 1 ATOM 5483 C CG . LEU A 1 693 ? 26.464 78.253 -28.056 1.00 17.49 ? 693 LEU A CG 1 ATOM 5484 C CD1 . LEU A 1 693 ? 25.027 78.471 -27.583 1.00 17.50 ? 693 LEU A CD1 1 ATOM 5485 C CD2 . LEU A 1 693 ? 27.310 77.720 -26.919 1.00 19.01 ? 693 LEU A CD2 1 ATOM 5486 N N . LEU A 1 694 ? 28.267 75.072 -30.874 1.00 14.83 ? 694 LEU A N 1 ATOM 5487 C CA . LEU A 1 694 ? 28.245 73.941 -31.765 1.00 15.40 ? 694 LEU A CA 1 ATOM 5488 C C . LEU A 1 694 ? 26.793 73.528 -32.076 1.00 13.45 ? 694 LEU A C 1 ATOM 5489 O O . LEU A 1 694 ? 25.916 73.559 -31.177 1.00 15.02 ? 694 LEU A O 1 ATOM 5490 C CB . LEU A 1 694 ? 29.000 72.772 -31.111 1.00 15.36 ? 694 LEU A CB 1 ATOM 5491 C CG . LEU A 1 694 ? 29.119 71.508 -31.950 1.00 16.02 ? 694 LEU A CG 1 ATOM 5492 C CD1 . LEU A 1 694 ? 30.034 71.752 -33.159 1.00 16.02 ? 694 LEU A CD1 1 ATOM 5493 C CD2 . LEU A 1 694 ? 29.729 70.381 -31.061 1.00 15.54 ? 694 LEU A CD2 1 ATOM 5494 N N . LYS A 1 695 ? 26.566 73.171 -33.344 1.00 14.39 ? 695 LYS A N 1 ATOM 5495 C CA . LYS A 1 695 ? 25.238 72.737 -33.833 1.00 16.26 ? 695 LYS A CA 1 ATOM 5496 C C . LYS A 1 695 ? 25.270 71.341 -34.431 1.00 15.21 ? 695 LYS A C 1 ATOM 5497 O O . LYS A 1 695 ? 24.309 70.581 -34.307 1.00 16.60 ? 695 LYS A O 1 ATOM 5498 C CB . LYS A 1 695 ? 24.779 73.723 -34.914 1.00 19.00 ? 695 LYS A CB 1 ATOM 5499 C CG . LYS A 1 695 ? 23.385 73.649 -35.379 1.00 26.19 ? 695 LYS A CG 1 ATOM 5500 C CD . LYS A 1 695 ? 23.255 74.725 -36.530 1.00 26.49 ? 695 LYS A CD 1 ATOM 5501 C CE . LYS A 1 695 ? 21.889 74.699 -37.239 1.00 31.18 ? 695 LYS A CE 1 ATOM 5502 N NZ . LYS A 1 695 ? 21.694 75.852 -38.214 1.00 31.60 ? 695 LYS A NZ 1 ATOM 5503 N N . SER A 1 696 ? 26.374 71.008 -35.087 1.00 15.74 ? 696 SER A N 1 ATOM 5504 C CA . SER A 1 696 ? 26.528 69.709 -35.694 1.00 16.33 ? 696 SER A CA 1 ATOM 5505 C C . SER A 1 696 ? 27.970 69.351 -35.932 1.00 16.12 ? 696 SER A C 1 ATOM 5506 O O . SER A 1 696 ? 28.876 70.224 -35.966 1.00 15.79 ? 696 SER A O 1 ATOM 5507 C CB . SER A 1 696 ? 25.751 69.597 -37.034 1.00 17.53 ? 696 SER A CB 1 ATOM 5508 O OG . SER A 1 696 ? 26.316 70.453 -38.013 1.00 18.75 ? 696 SER A OG 1 ATOM 5509 N N . ILE A 1 697 ? 28.192 68.050 -36.108 1.00 17.56 ? 697 ILE A N 1 ATOM 5510 C CA . ILE A 1 697 ? 29.514 67.513 -36.366 1.00 18.37 ? 697 ILE A CA 1 ATOM 5511 C C . ILE A 1 697 ? 29.397 66.550 -37.531 1.00 20.70 ? 697 ILE A C 1 ATOM 5512 O O . ILE A 1 697 ? 28.531 65.655 -37.537 1.00 21.91 ? 697 ILE A O 1 ATOM 5513 C CB . ILE A 1 697 ? 30.107 66.694 -35.144 1.00 16.76 ? 697 ILE A CB 1 ATOM 5514 C CG1 . ILE A 1 697 ? 30.194 67.572 -33.890 1.00 15.40 ? 697 ILE A CG1 1 ATOM 5515 C CG2 . ILE A 1 697 ? 31.470 66.085 -35.543 1.00 18.65 ? 697 ILE A CG2 1 ATOM 5516 C CD1 . ILE A 1 697 ? 30.732 66.815 -32.603 1.00 17.15 ? 697 ILE A CD1 1 ATOM 5517 N N . GLN A 1 698 ? 30.255 66.733 -38.520 1.00 21.77 ? 698 GLN A N 1 ATOM 5518 C CA . GLN A 1 698 ? 30.262 65.869 -39.684 1.00 24.11 ? 698 GLN A CA 1 ATOM 5519 C C . GLN A 1 698 ? 31.609 65.206 -39.669 1.00 24.72 ? 698 GLN A C 1 ATOM 5520 O O . GLN A 1 698 ? 32.638 65.868 -39.852 1.00 24.94 ? 698 GLN A O 1 ATOM 5521 C CB . GLN A 1 698 ? 30.074 66.663 -40.985 1.00 25.26 ? 698 GLN A CB 1 ATOM 5522 C CG . GLN A 1 698 ? 30.226 65.788 -42.219 1.00 28.56 ? 698 GLN A CG 1 ATOM 5523 C CD . GLN A 1 698 ? 30.166 66.596 -43.518 1.00 31.15 ? 698 GLN A CD 1 ATOM 5524 O OE1 . GLN A 1 698 ? 30.846 67.739 -43.537 1.00 32.90 ? 698 GLN A OE1 1 ATOM 5525 N NE2 . GLN A 1 698 ? 29.519 66.183 -44.494 1.00 30.59 ? 698 GLN A NE2 1 ATOM 5526 N N . LEU A 1 699 ? 31.591 63.901 -39.432 1.00 27.54 ? 699 LEU A N 1 ATOM 5527 C CA . LEU A 1 699 ? 32.813 63.124 -39.324 1.00 30.78 ? 699 LEU A CA 1 ATOM 5528 C C . LEU A 1 699 ? 33.676 63.060 -40.575 1.00 33.78 ? 699 LEU A C 1 ATOM 5529 O O . LEU A 1 699 ? 34.885 63.198 -40.490 1.00 33.68 ? 699 LEU A O 1 ATOM 5530 C CB . LEU A 1 699 ? 32.488 61.708 -38.832 1.00 29.76 ? 699 LEU A CB 1 ATOM 5531 C CG . LEU A 1 699 ? 31.952 61.541 -37.400 1.00 31.10 ? 699 LEU A CG 1 ATOM 5532 C CD1 . LEU A 1 699 ? 32.226 60.106 -37.005 1.00 30.14 ? 699 LEU A CD1 1 ATOM 5533 C CD2 . LEU A 1 699 ? 32.649 62.469 -36.402 1.00 30.91 ? 699 LEU A CD2 1 ATOM 5534 N N . THR A 1 700 ? 33.067 62.830 -41.730 1.00 37.18 ? 700 THR A N 1 ATOM 5535 C CA . THR A 1 700 ? 33.830 62.757 -42.973 1.00 40.66 ? 700 THR A CA 1 ATOM 5536 C C . THR A 1 700 ? 33.151 63.681 -43.952 1.00 42.76 ? 700 THR A C 1 ATOM 5537 O O . THR A 1 700 ? 31.981 64.015 -43.786 1.00 43.17 ? 700 THR A O 1 ATOM 5538 C CB . THR A 1 700 ? 33.849 61.339 -43.539 1.00 41.20 ? 700 THR A CB 1 ATOM 5539 O OG1 . THR A 1 700 ? 32.524 60.789 -43.483 1.00 42.46 ? 700 THR A OG1 1 ATOM 5540 C CG2 . THR A 1 700 ? 34.792 60.466 -42.742 1.00 41.09 ? 700 THR A CG2 1 ATOM 5541 N N . GLN A 1 701 ? 33.872 64.092 -44.979 1.00 45.39 ? 701 GLN A N 1 ATOM 5542 C CA . GLN A 1 701 ? 33.312 65.032 -45.936 1.00 48.01 ? 701 GLN A CA 1 ATOM 5543 C C . GLN A 1 701 ? 31.968 64.644 -46.584 1.00 48.32 ? 701 GLN A C 1 ATOM 5544 O O . GLN A 1 701 ? 31.210 65.525 -47.011 1.00 48.61 ? 701 GLN A O 1 ATOM 5545 C CB . GLN A 1 701 ? 34.343 65.323 -47.018 1.00 50.31 ? 701 GLN A CB 1 ATOM 5546 C CG . GLN A 1 701 ? 33.987 66.524 -47.853 1.00 53.62 ? 701 GLN A CG 1 ATOM 5547 C CD . GLN A 1 701 ? 34.830 66.602 -49.092 1.00 55.49 ? 701 GLN A CD 1 ATOM 5548 O OE1 . GLN A 1 701 ? 36.061 66.722 -49.012 1.00 56.54 ? 701 GLN A OE1 1 ATOM 5549 N NE2 . GLN A 1 701 ? 34.177 66.523 -50.261 1.00 56.22 ? 701 GLN A NE2 1 ATOM 5550 N N . ASP A 1 702 ? 31.661 63.345 -46.641 1.00 48.25 ? 702 ASP A N 1 ATOM 5551 C CA . ASP A 1 702 ? 30.404 62.882 -47.250 1.00 48.29 ? 702 ASP A CA 1 ATOM 5552 C C . ASP A 1 702 ? 29.281 62.413 -46.283 1.00 46.53 ? 702 ASP A C 1 ATOM 5553 O O . ASP A 1 702 ? 28.118 62.246 -46.700 1.00 45.94 ? 702 ASP A O 1 ATOM 5554 C CB . ASP A 1 702 ? 30.715 61.749 -48.232 1.00 51.23 ? 702 ASP A CB 1 ATOM 5555 C CG . ASP A 1 702 ? 31.403 60.575 -47.555 1.00 53.66 ? 702 ASP A CG 1 ATOM 5556 O OD1 . ASP A 1 702 ? 32.454 60.817 -46.910 1.00 55.03 ? 702 ASP A OD1 1 ATOM 5557 O OD2 . ASP A 1 702 ? 30.900 59.425 -47.660 1.00 54.80 ? 702 ASP A OD2 1 ATOM 5558 N N . SER A 1 703 ? 29.638 62.198 -45.015 1.00 43.66 ? 703 SER A N 1 ATOM 5559 C CA . SER A 1 703 ? 28.705 61.748 -43.976 1.00 40.55 ? 703 SER A CA 1 ATOM 5560 C C . SER A 1 703 ? 27.736 62.831 -43.528 1.00 38.56 ? 703 SER A C 1 ATOM 5561 O O . SER A 1 703 ? 27.919 64.009 -43.824 1.00 37.73 ? 703 SER A O 1 ATOM 5562 C CB . SER A 1 703 ? 29.487 61.243 -42.759 1.00 40.59 ? 703 SER A CB 1 ATOM 5563 O OG . SER A 1 703 ? 30.314 62.251 -42.201 1.00 39.94 ? 703 SER A OG 1 ATOM 5564 N N . PRO A 1 704 ? 26.689 62.441 -42.788 1.00 36.94 ? 704 PRO A N 1 ATOM 5565 C CA . PRO A 1 704 ? 25.698 63.393 -42.309 1.00 35.40 ? 704 PRO A CA 1 ATOM 5566 C C . PRO A 1 704 ? 26.194 64.315 -41.220 1.00 33.78 ? 704 PRO A C 1 ATOM 5567 O O . PRO A 1 704 ? 27.172 64.027 -40.536 1.00 34.00 ? 704 PRO A O 1 ATOM 5568 C CB . PRO A 1 704 ? 24.551 62.507 -41.846 1.00 35.98 ? 704 PRO A CB 1 ATOM 5569 C CG . PRO A 1 704 ? 25.204 61.271 -41.452 1.00 37.19 ? 704 PRO A CG 1 ATOM 5570 C CD . PRO A 1 704 ? 26.295 61.061 -42.456 1.00 36.85 ? 704 PRO A CD 1 ATOM 5571 N N . HIS A 1 705 ? 25.511 65.447 -41.097 1.00 31.30 ? 705 HIS A N 1 ATOM 5572 C CA . HIS A 1 705 ? 25.828 66.439 -40.094 1.00 29.12 ? 705 HIS A CA 1 ATOM 5573 C C . HIS A 1 705 ? 25.001 66.028 -38.901 1.00 26.61 ? 705 HIS A C 1 ATOM 5574 O O . HIS A 1 705 ? 23.811 66.334 -38.798 1.00 26.12 ? 705 HIS A O 1 ATOM 5575 C CB . HIS A 1 705 ? 25.422 67.826 -40.571 1.00 30.14 ? 705 HIS A CB 1 ATOM 5576 C CG . HIS A 1 705 ? 26.242 68.321 -41.721 1.00 32.70 ? 705 HIS A CG 1 ATOM 5577 N ND1 . HIS A 1 705 ? 27.444 68.976 -41.557 1.00 33.34 ? 705 HIS A ND1 1 ATOM 5578 C CD2 . HIS A 1 705 ? 26.033 68.250 -43.057 1.00 32.98 ? 705 HIS A CD2 1 ATOM 5579 C CE1 . HIS A 1 705 ? 27.937 69.294 -42.740 1.00 35.17 ? 705 HIS A CE1 1 ATOM 5580 N NE2 . HIS A 1 705 ? 27.097 68.865 -43.668 1.00 34.57 ? 705 HIS A NE2 1 ATOM 5581 N N . VAL A 1 706 ? 25.649 65.311 -37.995 1.00 23.51 ? 706 VAL A N 1 ATOM 5582 C CA . VAL A 1 706 ? 24.994 64.807 -36.810 1.00 21.27 ? 706 VAL A CA 1 ATOM 5583 C C . VAL A 1 706 ? 24.698 65.948 -35.852 1.00 19.63 ? 706 VAL A C 1 ATOM 5584 O O . VAL A 1 706 ? 25.623 66.640 -35.445 1.00 18.46 ? 706 VAL A O 1 ATOM 5585 C CB . VAL A 1 706 ? 25.938 63.821 -36.099 1.00 21.18 ? 706 VAL A CB 1 ATOM 5586 C CG1 . VAL A 1 706 ? 25.252 63.229 -34.891 1.00 20.28 ? 706 VAL A CG1 1 ATOM 5587 C CG2 . VAL A 1 706 ? 26.384 62.743 -37.060 1.00 21.28 ? 706 VAL A CG2 1 ATOM 5588 N N . PRO A 1 707 ? 23.419 66.161 -35.477 1.00 18.52 ? 707 PRO A N 1 ATOM 5589 C CA . PRO A 1 707 ? 23.013 67.225 -34.546 1.00 17.97 ? 707 PRO A CA 1 ATOM 5590 C C . PRO A 1 707 ? 23.720 66.993 -33.196 1.00 18.43 ? 707 PRO A C 1 ATOM 5591 O O . PRO A 1 707 ? 23.646 65.907 -32.634 1.00 19.00 ? 707 PRO A O 1 ATOM 5592 C CB . PRO A 1 707 ? 21.509 67.048 -34.422 1.00 16.00 ? 707 PRO A CB 1 ATOM 5593 C CG . PRO A 1 707 ? 21.103 66.427 -35.741 1.00 20.26 ? 707 PRO A CG 1 ATOM 5594 C CD . PRO A 1 707 ? 22.241 65.495 -36.094 1.00 18.00 ? 707 PRO A CD 1 ATOM 5595 N N . VAL A 1 708 ? 24.461 67.997 -32.750 1.00 17.27 ? 708 VAL A N 1 ATOM 5596 C CA . VAL A 1 708 ? 25.208 67.985 -31.477 1.00 16.72 ? 708 VAL A CA 1 ATOM 5597 C C . VAL A 1 708 ? 25.212 69.463 -31.080 1.00 16.74 ? 708 VAL A C 1 ATOM 5598 O O . VAL A 1 708 ? 25.988 70.316 -31.597 1.00 15.71 ? 708 VAL A O 1 ATOM 5599 C CB . VAL A 1 708 ? 26.671 67.464 -31.620 1.00 15.13 ? 708 VAL A CB 1 ATOM 5600 C CG1 . VAL A 1 708 ? 27.346 67.507 -30.180 1.00 16.04 ? 708 VAL A CG1 1 ATOM 5601 C CG2 . VAL A 1 708 ? 26.687 66.023 -32.151 1.00 15.80 ? 708 VAL A CG2 1 ATOM 5602 N N . HIS A 1 709 ? 24.327 69.792 -30.148 1.00 16.05 ? 709 HIS A N 1 ATOM 5603 C CA . HIS A 1 709 ? 24.143 71.187 -29.732 1.00 17.43 ? 709 HIS A CA 1 ATOM 5604 C C . HIS A 1 709 ? 24.558 71.529 -28.292 1.00 17.17 ? 709 HIS A C 1 ATOM 5605 O O . HIS A 1 709 ? 24.039 70.925 -27.348 1.00 16.12 ? 709 HIS A O 1 ATOM 5606 C CB A HIS A 1 709 ? 22.656 71.567 -29.888 0.50 19.73 ? 709 HIS A CB 1 ATOM 5607 C CB B HIS A 1 709 ? 22.811 71.697 -30.027 0.50 18.93 ? 709 HIS A CB 1 ATOM 5608 C CG A HIS A 1 709 ? 22.112 71.420 -31.278 0.50 21.64 ? 709 HIS A CG 1 ATOM 5609 C CG B HIS A 1 709 ? 22.581 73.131 -29.650 0.50 20.53 ? 709 HIS A CG 1 ATOM 5610 N ND1 A HIS A 1 709 ? 21.998 72.480 -32.150 0.50 23.75 ? 709 HIS A ND1 1 ATOM 5611 N ND1 B HIS A 1 709 ? 23.336 74.167 -30.162 0.50 19.72 ? 709 HIS A ND1 1 ATOM 5612 C CD2 A HIS A 1 709 ? 21.634 70.341 -31.939 0.50 23.16 ? 709 HIS A CD2 1 ATOM 5613 C CD2 B HIS A 1 709 ? 21.681 73.700 -28.813 0.50 21.61 ? 709 HIS A CD2 1 ATOM 5614 C CE1 A HIS A 1 709 ? 21.475 72.061 -33.286 0.50 22.91 ? 709 HIS A CE1 1 ATOM 5615 C CE1 B HIS A 1 709 ? 22.914 75.310 -29.653 0.50 22.23 ? 709 HIS A CE1 1 ATOM 5616 N NE2 A HIS A 1 709 ? 21.247 70.765 -33.185 0.50 22.95 ? 709 HIS A NE2 1 ATOM 5617 N NE2 B HIS A 1 709 ? 21.911 75.056 -28.831 0.50 22.41 ? 709 HIS A NE2 1 ATOM 5618 N N . PHE A 1 710 ? 25.462 72.499 -28.120 1.00 16.30 ? 710 PHE A N 1 ATOM 5619 C CA . PHE A 1 710 ? 25.861 72.937 -26.785 1.00 15.38 ? 710 PHE A CA 1 ATOM 5620 C C . PHE A 1 710 ? 24.846 73.997 -26.400 1.00 17.01 ? 710 PHE A C 1 ATOM 5621 O O . PHE A 1 710 ? 24.411 74.823 -27.253 1.00 15.94 ? 710 PHE A O 1 ATOM 5622 C CB . PHE A 1 710 ? 27.261 73.577 -26.739 1.00 15.76 ? 710 PHE A CB 1 ATOM 5623 C CG . PHE A 1 710 ? 28.377 72.611 -26.383 1.00 16.32 ? 710 PHE A CG 1 ATOM 5624 C CD1 . PHE A 1 710 ? 28.385 71.909 -25.182 1.00 18.38 ? 710 PHE A CD1 1 ATOM 5625 C CD2 . PHE A 1 710 ? 29.433 72.417 -27.260 1.00 17.57 ? 710 PHE A CD2 1 ATOM 5626 C CE1 . PHE A 1 710 ? 29.451 71.034 -24.882 1.00 18.65 ? 710 PHE A CE1 1 ATOM 5627 C CE2 . PHE A 1 710 ? 30.471 71.557 -26.950 1.00 17.17 ? 710 PHE A CE2 1 ATOM 5628 C CZ . PHE A 1 710 ? 30.484 70.880 -25.778 1.00 16.69 ? 710 PHE A CZ 1 ATOM 5629 N N . LYS A 1 711 ? 24.462 73.985 -25.124 1.00 14.45 ? 711 LYS A N 1 ATOM 5630 C CA . LYS A 1 711 ? 23.503 74.942 -24.584 1.00 15.21 ? 711 LYS A CA 1 ATOM 5631 C C . LYS A 1 711 ? 23.849 75.171 -23.124 1.00 15.07 ? 711 LYS A C 1 ATOM 5632 O O . LYS A 1 711 ? 24.229 74.224 -22.396 1.00 18.23 ? 711 LYS A O 1 ATOM 5633 C CB . LYS A 1 711 ? 22.059 74.398 -24.689 1.00 16.03 ? 711 LYS A CB 1 ATOM 5634 C CG . LYS A 1 711 ? 20.977 75.393 -24.362 1.00 17.97 ? 711 LYS A CG 1 ATOM 5635 C CD . LYS A 1 711 ? 19.560 74.741 -24.439 1.00 22.21 ? 711 LYS A CD 1 ATOM 5636 C CE . LYS A 1 711 ? 19.033 74.663 -25.877 1.00 24.20 ? 711 LYS A CE 1 ATOM 5637 N NZ . LYS A 1 711 ? 17.646 74.050 -25.970 1.00 27.31 ? 711 LYS A NZ 1 ATOM 5638 N N . PHE A 1 712 ? 23.727 76.396 -22.653 1.00 14.17 ? 712 PHE A N 1 ATOM 5639 C CA . PHE A 1 712 ? 23.999 76.689 -21.255 1.00 12.78 ? 712 PHE A CA 1 ATOM 5640 C C . PHE A 1 712 ? 22.710 77.045 -20.554 1.00 14.26 ? 712 PHE A C 1 ATOM 5641 O O . PHE A 1 712 ? 21.890 77.827 -21.093 1.00 14.07 ? 712 PHE A O 1 ATOM 5642 C CB . PHE A 1 712 ? 25.012 77.831 -21.108 1.00 14.20 ? 712 PHE A CB 1 ATOM 5643 C CG . PHE A 1 712 ? 26.425 77.410 -21.428 1.00 12.34 ? 712 PHE A CG 1 ATOM 5644 C CD1 . PHE A 1 712 ? 26.892 77.449 -22.764 1.00 13.43 ? 712 PHE A CD1 1 ATOM 5645 C CD2 . PHE A 1 712 ? 27.265 76.941 -20.433 1.00 13.62 ? 712 PHE A CD2 1 ATOM 5646 C CE1 . PHE A 1 712 ? 28.183 77.036 -23.085 1.00 10.21 ? 712 PHE A CE1 1 ATOM 5647 C CE2 . PHE A 1 712 ? 28.557 76.523 -20.729 1.00 11.37 ? 712 PHE A CE2 1 ATOM 5648 C CZ . PHE A 1 712 ? 29.041 76.564 -22.038 1.00 12.81 ? 712 PHE A CZ 1 ATOM 5649 N N . LEU A 1 713 ? 22.469 76.432 -19.398 1.00 12.13 ? 713 LEU A N 1 ATOM 5650 C CA . LEU A 1 713 ? 21.229 76.678 -18.640 1.00 13.77 ? 713 LEU A CA 1 ATOM 5651 C C . LEU A 1 713 ? 21.564 76.920 -17.186 1.00 12.43 ? 713 LEU A C 1 ATOM 5652 O O . LEU A 1 713 ? 22.758 76.840 -16.780 1.00 13.20 ? 713 LEU A O 1 ATOM 5653 C CB . LEU A 1 713 ? 20.259 75.503 -18.757 1.00 11.24 ? 713 LEU A CB 1 ATOM 5654 C CG . LEU A 1 713 ? 19.971 74.997 -20.174 1.00 13.39 ? 713 LEU A CG 1 ATOM 5655 C CD1 . LEU A 1 713 ? 20.914 73.881 -20.521 1.00 15.50 ? 713 LEU A CD1 1 ATOM 5656 C CD2 . LEU A 1 713 ? 18.477 74.490 -20.270 1.00 14.44 ? 713 LEU A CD2 1 ATOM 5657 N N . LYS A 1 714 ? 20.564 77.290 -16.408 1.00 13.70 ? 714 LYS A N 1 ATOM 5658 C CA . LYS A 1 714 ? 20.793 77.510 -14.997 1.00 14.28 ? 714 LYS A CA 1 ATOM 5659 C C . LYS A 1 714 ? 19.732 76.890 -14.141 1.00 15.21 ? 714 LYS A C 1 ATOM 5660 O O . LYS A 1 714 ? 18.567 76.815 -14.551 1.00 14.94 ? 714 LYS A O 1 ATOM 5661 C CB . LYS A 1 714 ? 20.895 78.978 -14.646 1.00 20.83 ? 714 LYS A CB 1 ATOM 5662 C CG . LYS A 1 714 ? 19.690 79.765 -14.914 1.00 25.32 ? 714 LYS A CG 1 ATOM 5663 C CD . LYS A 1 714 ? 20.033 81.224 -14.603 1.00 29.68 ? 714 LYS A CD 1 ATOM 5664 C CE . LYS A 1 714 ? 21.197 81.705 -15.496 1.00 32.19 ? 714 LYS A CE 1 ATOM 5665 N NZ . LYS A 1 714 ? 21.657 83.099 -15.177 1.00 34.64 ? 714 LYS A NZ 1 ATOM 5666 N N . TYR A 1 715 ? 20.176 76.389 -12.983 1.00 12.72 ? 715 TYR A N 1 ATOM 5667 C CA . TYR A 1 715 ? 19.326 75.814 -11.961 1.00 12.71 ? 715 TYR A CA 1 ATOM 5668 C C . TYR A 1 715 ? 19.249 76.838 -10.845 1.00 12.86 ? 715 TYR A C 1 ATOM 5669 O O . TYR A 1 715 ? 20.209 77.560 -10.572 1.00 13.71 ? 715 TYR A O 1 ATOM 5670 C CB . TYR A 1 715 ? 19.916 74.506 -11.352 1.00 12.85 ? 715 TYR A CB 1 ATOM 5671 C CG . TYR A 1 715 ? 19.836 73.362 -12.289 1.00 11.65 ? 715 TYR A CG 1 ATOM 5672 C CD1 . TYR A 1 715 ? 18.637 72.610 -12.374 1.00 8.48 ? 715 TYR A CD1 1 ATOM 5673 C CD2 . TYR A 1 715 ? 20.958 72.948 -13.042 1.00 9.42 ? 715 TYR A CD2 1 ATOM 5674 C CE1 . TYR A 1 715 ? 18.562 71.504 -13.139 1.00 10.86 ? 715 TYR A CE1 1 ATOM 5675 C CE2 . TYR A 1 715 ? 20.882 71.816 -13.849 1.00 11.09 ? 715 TYR A CE2 1 ATOM 5676 C CZ . TYR A 1 715 ? 19.675 71.090 -13.887 1.00 10.32 ? 715 TYR A CZ 1 ATOM 5677 O OH . TYR A 1 715 ? 19.548 69.940 -14.576 1.00 13.20 ? 715 TYR A OH 1 ATOM 5678 N N . GLY A 1 716 ? 18.116 76.904 -10.172 1.00 15.00 ? 716 GLY A N 1 ATOM 5679 C CA . GLY A 1 716 ? 17.976 77.794 -9.060 1.00 14.66 ? 716 GLY A CA 1 ATOM 5680 C C . GLY A 1 716 ? 17.890 77.024 -7.755 1.00 15.59 ? 716 GLY A C 1 ATOM 5681 O O . GLY A 1 716 ? 18.241 75.811 -7.622 1.00 16.05 ? 716 GLY A O 1 ATOM 5682 N N . VAL A 1 717 ? 17.413 77.735 -6.753 1.00 16.12 ? 717 VAL A N 1 ATOM 5683 C CA . VAL A 1 717 ? 17.251 77.204 -5.417 1.00 16.74 ? 717 VAL A CA 1 ATOM 5684 C C . VAL A 1 717 ? 15.839 77.343 -4.862 1.00 19.91 ? 717 VAL A C 1 ATOM 5685 O O . VAL A 1 717 ? 15.129 78.272 -5.230 1.00 21.49 ? 717 VAL A O 1 ATOM 5686 C CB . VAL A 1 717 ? 18.211 77.889 -4.483 1.00 17.55 ? 717 VAL A CB 1 ATOM 5687 C CG1 . VAL A 1 717 ? 18.019 77.407 -3.124 1.00 19.95 ? 717 VAL A CG1 1 ATOM 5688 C CG2 . VAL A 1 717 ? 19.659 77.634 -4.936 1.00 15.70 ? 717 VAL A CG2 1 ATOM 5689 N N . ARG A 1 718 ? 15.412 76.433 -3.987 1.00 19.49 ? 718 ARG A N 1 ATOM 5690 C CA . ARG A 1 718 ? 14.047 76.517 -3.409 1.00 21.46 ? 718 ARG A CA 1 ATOM 5691 C C . ARG A 1 718 ? 13.860 77.696 -2.445 1.00 23.39 ? 718 ARG A C 1 ATOM 5692 O O . ARG A 1 718 ? 14.710 77.994 -1.623 1.00 23.18 ? 718 ARG A O 1 ATOM 5693 C CB . ARG A 1 718 ? 13.677 75.196 -2.704 1.00 20.03 ? 718 ARG A CB 1 ATOM 5694 C CG . ARG A 1 718 ? 13.585 74.061 -3.678 1.00 17.40 ? 718 ARG A CG 1 ATOM 5695 C CD . ARG A 1 718 ? 13.602 72.691 -2.980 1.00 16.81 ? 718 ARG A CD 1 ATOM 5696 N NE . ARG A 1 718 ? 13.906 71.687 -3.975 1.00 15.05 ? 718 ARG A NE 1 ATOM 5697 C CZ . ARG A 1 718 ? 13.836 70.358 -3.835 1.00 13.99 ? 718 ARG A CZ 1 ATOM 5698 N NH1 . ARG A 1 718 ? 13.436 69.805 -2.697 1.00 13.27 ? 718 ARG A NH1 1 ATOM 5699 N NH2 . ARG A 1 718 ? 14.219 69.609 -4.832 1.00 17.47 ? 718 ARG A NH2 1 ATOM 5700 N N . SER A 1 719 ? 12.720 78.376 -2.557 1.00 27.09 ? 719 SER A N 1 ATOM 5701 C CA . SER A 1 719 ? 12.428 79.518 -1.682 1.00 30.90 ? 719 SER A CA 1 ATOM 5702 C C . SER A 1 719 ? 11.868 79.108 -0.309 1.00 32.55 ? 719 SER A C 1 ATOM 5703 O O . SER A 1 719 ? 12.053 79.819 0.684 1.00 32.61 ? 719 SER A O 1 ATOM 5704 C CB . SER A 1 719 ? 11.456 80.475 -2.390 1.00 32.24 ? 719 SER A CB 1 ATOM 5705 O OG . SER A 1 719 ? 10.549 79.760 -3.236 1.00 34.64 ? 719 SER A OG 1 ATOM 5706 N N . HIS A 1 720 ? 11.181 77.966 -0.286 1.00 33.79 ? 720 HIS A N 1 ATOM 5707 C CA . HIS A 1 720 ? 10.604 77.374 0.918 1.00 35.36 ? 720 HIS A CA 1 ATOM 5708 C C . HIS A 1 720 ? 11.033 75.904 0.873 1.00 34.69 ? 720 HIS A C 1 ATOM 5709 O O . HIS A 1 720 ? 11.052 75.266 -0.202 1.00 36.78 ? 720 HIS A O 1 ATOM 5710 C CB . HIS A 1 720 ? 9.079 77.463 0.882 1.00 38.51 ? 720 HIS A CB 1 ATOM 5711 C CG . HIS A 1 720 ? 8.473 76.806 -0.318 1.00 42.04 ? 720 HIS A CG 1 ATOM 5712 N ND1 . HIS A 1 720 ? 8.740 77.225 -1.609 1.00 43.73 ? 720 HIS A ND1 1 ATOM 5713 C CD2 . HIS A 1 720 ? 7.628 75.751 -0.429 1.00 43.30 ? 720 HIS A CD2 1 ATOM 5714 C CE1 . HIS A 1 720 ? 8.082 76.456 -2.461 1.00 44.24 ? 720 HIS A CE1 1 ATOM 5715 N NE2 . HIS A 1 720 ? 7.402 75.554 -1.772 1.00 44.32 ? 720 HIS A NE2 1 ATOM 5716 N N . GLY A 1 721 ? 11.381 75.361 2.025 1.00 32.32 ? 721 GLY A N 1 ATOM 5717 C CA . GLY A 1 721 ? 11.824 73.980 2.041 1.00 27.97 ? 721 GLY A CA 1 ATOM 5718 C C . GLY A 1 721 ? 13.347 73.973 2.159 1.00 24.21 ? 721 GLY A C 1 ATOM 5719 O O . GLY A 1 721 ? 13.969 75.026 2.335 1.00 22.68 ? 721 GLY A O 1 ATOM 5720 N N . ASP A 1 722 ? 13.953 72.802 2.012 1.00 20.75 ? 722 ASP A N 1 ATOM 5721 C CA . ASP A 1 722 ? 15.398 72.674 2.167 1.00 20.26 ? 722 ASP A CA 1 ATOM 5722 C C . ASP A 1 722 ? 16.175 73.349 1.043 1.00 17.40 ? 722 ASP A C 1 ATOM 5723 O O . ASP A 1 722 ? 15.806 73.273 -0.117 1.00 18.01 ? 722 ASP A O 1 ATOM 5724 C CB . ASP A 1 722 ? 15.771 71.198 2.200 1.00 18.40 ? 722 ASP A CB 1 ATOM 5725 C CG . ASP A 1 722 ? 15.157 70.466 3.383 1.00 19.93 ? 722 ASP A CG 1 ATOM 5726 O OD1 . ASP A 1 722 ? 14.927 71.099 4.457 1.00 18.38 ? 722 ASP A OD1 1 ATOM 5727 O OD2 . ASP A 1 722 ? 14.928 69.235 3.213 1.00 18.22 ? 722 ASP A OD2 1 ATOM 5728 N N . ARG A 1 723 ? 17.256 74.035 1.398 1.00 17.16 ? 723 ARG A N 1 ATOM 5729 C CA . ARG A 1 723 ? 18.079 74.709 0.395 1.00 17.08 ? 723 ARG A CA 1 ATOM 5730 C C . ARG A 1 723 ? 19.385 73.992 0.018 1.00 13.92 ? 723 ARG A C 1 ATOM 5731 O O . ARG A 1 723 ? 20.031 73.353 0.850 1.00 14.12 ? 723 ARG A O 1 ATOM 5732 C CB . ARG A 1 723 ? 18.497 76.081 0.894 1.00 17.69 ? 723 ARG A CB 1 ATOM 5733 C CG . ARG A 1 723 ? 17.473 77.184 0.716 1.00 26.07 ? 723 ARG A CG 1 ATOM 5734 C CD . ARG A 1 723 ? 16.237 76.957 1.553 1.00 29.58 ? 723 ARG A CD 1 ATOM 5735 N NE . ARG A 1 723 ? 15.379 78.155 1.594 1.00 34.02 ? 723 ARG A NE 1 ATOM 5736 C CZ . ARG A 1 723 ? 15.838 79.398 1.750 1.00 35.11 ? 723 ARG A CZ 1 ATOM 5737 N NH1 . ARG A 1 723 ? 17.150 79.620 1.874 1.00 35.86 ? 723 ARG A NH1 1 ATOM 5738 N NH2 . ARG A 1 723 ? 14.985 80.418 1.806 1.00 35.73 ? 723 ARG A NH2 1 ATOM 5739 N N . SER A 1 724 ? 19.754 74.140 -1.239 1.00 14.73 ? 724 SER A N 1 ATOM 5740 C CA . SER A 1 724 ? 21.023 73.631 -1.713 1.00 12.84 ? 724 SER A CA 1 ATOM 5741 C C . SER A 1 724 ? 22.123 74.322 -0.921 1.00 14.00 ? 724 SER A C 1 ATOM 5742 O O . SER A 1 724 ? 21.994 75.461 -0.508 1.00 15.59 ? 724 SER A O 1 ATOM 5743 C CB . SER A 1 724 ? 21.199 73.995 -3.157 1.00 12.81 ? 724 SER A CB 1 ATOM 5744 O OG . SER A 1 724 ? 20.143 73.417 -3.919 1.00 13.22 ? 724 SER A OG 1 ATOM 5745 N N . GLY A 1 725 ? 23.216 73.607 -0.695 1.00 13.96 ? 725 GLY A N 1 ATOM 5746 C CA . GLY A 1 725 ? 24.373 74.156 -0.015 1.00 12.99 ? 725 GLY A CA 1 ATOM 5747 C C . GLY A 1 725 ? 25.585 73.447 -0.652 1.00 9.42 ? 725 GLY A C 1 ATOM 5748 O O . GLY A 1 725 ? 25.482 72.842 -1.762 1.00 11.32 ? 725 GLY A O 1 ATOM 5749 N N . ALA A 1 726 ? 26.719 73.473 0.062 1.00 11.43 ? 726 ALA A N 1 ATOM 5750 C CA . ALA A 1 726 ? 27.943 72.866 -0.442 1.00 9.44 ? 726 ALA A CA 1 ATOM 5751 C C . ALA A 1 726 ? 27.837 71.343 -0.702 1.00 10.07 ? 726 ALA A C 1 ATOM 5752 O O . ALA A 1 726 ? 28.514 70.817 -1.609 1.00 9.53 ? 726 ALA A O 1 ATOM 5753 C CB . ALA A 1 726 ? 29.122 73.156 0.559 1.00 10.11 ? 726 ALA A CB 1 ATOM 5754 N N . TYR A 1 727 ? 26.972 70.690 0.068 1.00 8.91 ? 727 TYR A N 1 ATOM 5755 C CA . TYR A 1 727 ? 26.783 69.247 -0.085 1.00 9.44 ? 727 TYR A CA 1 ATOM 5756 C C . TYR A 1 727 ? 25.610 68.910 -0.982 1.00 7.24 ? 727 TYR A C 1 ATOM 5757 O O . TYR A 1 727 ? 25.712 68.103 -1.898 1.00 8.91 ? 727 TYR A O 1 ATOM 5758 C CB . TYR A 1 727 ? 26.497 68.580 1.273 1.00 9.58 ? 727 TYR A CB 1 ATOM 5759 C CG . TYR A 1 727 ? 27.505 68.859 2.387 1.00 8.64 ? 727 TYR A CG 1 ATOM 5760 C CD1 . TYR A 1 727 ? 27.396 70.005 3.214 1.00 8.88 ? 727 TYR A CD1 1 ATOM 5761 C CD2 . TYR A 1 727 ? 28.583 67.958 2.594 1.00 7.91 ? 727 TYR A CD2 1 ATOM 5762 C CE1 . TYR A 1 727 ? 28.348 70.258 4.263 1.00 8.51 ? 727 TYR A CE1 1 ATOM 5763 C CE2 . TYR A 1 727 ? 29.532 68.207 3.615 1.00 8.60 ? 727 TYR A CE2 1 ATOM 5764 C CZ . TYR A 1 727 ? 29.403 69.353 4.437 1.00 8.39 ? 727 TYR A CZ 1 ATOM 5765 O OH . TYR A 1 727 ? 30.279 69.520 5.462 1.00 9.37 ? 727 TYR A OH 1 ATOM 5766 N N . LEU A 1 728 ? 24.470 69.527 -0.665 1.00 10.77 ? 728 LEU A N 1 ATOM 5767 C CA . LEU A 1 728 ? 23.203 69.183 -1.311 1.00 10.20 ? 728 LEU A CA 1 ATOM 5768 C C . LEU A 1 728 ? 22.818 69.939 -2.563 1.00 10.04 ? 728 LEU A C 1 ATOM 5769 O O . LEU A 1 728 ? 22.991 71.186 -2.577 1.00 10.48 ? 728 LEU A O 1 ATOM 5770 C CB . LEU A 1 728 ? 22.046 69.359 -0.306 1.00 12.03 ? 728 LEU A CB 1 ATOM 5771 C CG . LEU A 1 728 ? 22.147 68.731 1.098 1.00 10.59 ? 728 LEU A CG 1 ATOM 5772 C CD1 . LEU A 1 728 ? 20.758 68.897 1.899 1.00 9.91 ? 728 LEU A CD1 1 ATOM 5773 C CD2 . LEU A 1 728 ? 22.463 67.192 0.997 1.00 10.99 ? 728 LEU A CD2 1 ATOM 5774 N N . PHE A 1 729 ? 22.277 69.244 -3.559 1.00 9.83 ? 729 PHE A N 1 ATOM 5775 C CA . PHE A 1 729 ? 21.787 69.872 -4.792 1.00 11.02 ? 729 PHE A CA 1 ATOM 5776 C C . PHE A 1 729 ? 20.234 69.676 -4.714 1.00 12.07 ? 729 PHE A C 1 ATOM 5777 O O . PHE A 1 729 ? 19.734 68.544 -4.833 1.00 10.12 ? 729 PHE A O 1 ATOM 5778 C CB . PHE A 1 729 ? 22.355 69.137 -6.027 1.00 10.83 ? 729 PHE A CB 1 ATOM 5779 C CG . PHE A 1 729 ? 21.798 69.608 -7.371 1.00 10.70 ? 729 PHE A CG 1 ATOM 5780 C CD1 . PHE A 1 729 ? 21.431 70.954 -7.600 1.00 10.44 ? 729 PHE A CD1 1 ATOM 5781 C CD2 . PHE A 1 729 ? 21.698 68.725 -8.404 1.00 8.58 ? 729 PHE A CD2 1 ATOM 5782 C CE1 . PHE A 1 729 ? 20.972 71.349 -8.881 1.00 11.79 ? 729 PHE A CE1 1 ATOM 5783 C CE2 . PHE A 1 729 ? 21.257 69.101 -9.683 1.00 10.04 ? 729 PHE A CE2 1 ATOM 5784 C CZ . PHE A 1 729 ? 20.894 70.459 -9.888 1.00 10.56 ? 729 PHE A CZ 1 ATOM 5785 N N . LEU A 1 730 ? 19.477 70.773 -4.513 1.00 12.81 ? 730 LEU A N 1 ATOM 5786 C CA . LEU A 1 730 ? 18.006 70.684 -4.369 1.00 13.80 ? 730 LEU A CA 1 ATOM 5787 C C . LEU A 1 730 ? 17.431 71.752 -5.296 1.00 12.34 ? 730 LEU A C 1 ATOM 5788 O O . LEU A 1 730 ? 16.985 72.836 -4.849 1.00 12.90 ? 730 LEU A O 1 ATOM 5789 C CB . LEU A 1 730 ? 17.620 70.941 -2.921 1.00 13.04 ? 730 LEU A CB 1 ATOM 5790 C CG . LEU A 1 730 ? 18.061 69.916 -1.859 1.00 12.72 ? 730 LEU A CG 1 ATOM 5791 C CD1 . LEU A 1 730 ? 18.145 70.507 -0.450 1.00 13.55 ? 730 LEU A CD1 1 ATOM 5792 C CD2 . LEU A 1 730 ? 17.052 68.790 -1.845 1.00 12.42 ? 730 LEU A CD2 1 ATOM 5793 N N . PRO A 1 731 ? 17.468 71.453 -6.585 1.00 13.59 ? 731 PRO A N 1 ATOM 5794 C CA . PRO A 1 731 ? 16.961 72.414 -7.579 1.00 14.01 ? 731 PRO A CA 1 ATOM 5795 C C . PRO A 1 731 ? 15.477 72.688 -7.471 1.00 15.47 ? 731 PRO A C 1 ATOM 5796 O O . PRO A 1 731 ? 14.690 71.840 -7.007 1.00 14.53 ? 731 PRO A O 1 ATOM 5797 C CB . PRO A 1 731 ? 17.287 71.765 -8.906 1.00 14.42 ? 731 PRO A CB 1 ATOM 5798 C CG . PRO A 1 731 ? 17.217 70.244 -8.592 1.00 13.37 ? 731 PRO A CG 1 ATOM 5799 C CD . PRO A 1 731 ? 17.826 70.159 -7.198 1.00 13.98 ? 731 PRO A CD 1 ATOM 5800 N N . ASN A 1 732 ? 15.104 73.888 -7.916 1.00 16.34 ? 732 ASN A N 1 ATOM 5801 C CA . ASN A 1 732 ? 13.699 74.262 -7.993 1.00 18.51 ? 732 ASN A CA 1 ATOM 5802 C C . ASN A 1 732 ? 13.208 73.996 -9.390 1.00 17.45 ? 732 ASN A C 1 ATOM 5803 O O . ASN A 1 732 ? 12.775 74.921 -10.101 1.00 20.01 ? 732 ASN A O 1 ATOM 5804 C CB . ASN A 1 732 ? 13.521 75.731 -7.634 1.00 20.70 ? 732 ASN A CB 1 ATOM 5805 C CG . ASN A 1 732 ? 14.191 76.670 -8.606 1.00 23.89 ? 732 ASN A CG 1 ATOM 5806 O OD1 . ASN A 1 732 ? 15.200 76.357 -9.256 1.00 23.42 ? 732 ASN A OD1 1 ATOM 5807 N ND2 . ASN A 1 732 ? 13.625 77.869 -8.706 1.00 27.31 ? 732 ASN A ND2 1 ATOM 5808 N N . GLY A 1 733 ? 13.272 72.741 -9.806 1.00 16.42 ? 733 GLY A N 1 ATOM 5809 C CA . GLY A 1 733 ? 12.814 72.342 -11.124 1.00 16.61 ? 733 GLY A CA 1 ATOM 5810 C C . GLY A 1 733 ? 13.924 72.211 -12.144 1.00 16.30 ? 733 GLY A C 1 ATOM 5811 O O . GLY A 1 733 ? 15.114 72.492 -11.851 1.00 17.66 ? 733 GLY A O 1 ATOM 5812 N N . PRO A 1 734 ? 13.589 71.758 -13.344 1.00 16.48 ? 734 PRO A N 1 ATOM 5813 C CA . PRO A 1 734 ? 14.531 71.587 -14.439 1.00 15.53 ? 734 PRO A CA 1 ATOM 5814 C C . PRO A 1 734 ? 15.171 72.944 -14.716 1.00 14.91 ? 734 PRO A C 1 ATOM 5815 O O . PRO A 1 734 ? 14.589 74.000 -14.474 1.00 15.96 ? 734 PRO A O 1 ATOM 5816 C CB . PRO A 1 734 ? 13.657 71.143 -15.601 1.00 17.17 ? 734 PRO A CB 1 ATOM 5817 C CG . PRO A 1 734 ? 12.546 70.399 -14.913 1.00 19.80 ? 734 PRO A CG 1 ATOM 5818 C CD . PRO A 1 734 ? 12.243 71.311 -13.748 1.00 16.58 ? 734 PRO A CD 1 ATOM 5819 N N . ALA A 1 735 ? 16.376 72.918 -15.232 1.00 12.41 ? 735 ALA A N 1 ATOM 5820 C CA . ALA A 1 735 ? 17.093 74.171 -15.519 1.00 14.43 ? 735 ALA A CA 1 ATOM 5821 C C . ALA A 1 735 ? 16.399 75.043 -16.591 1.00 15.58 ? 735 ALA A C 1 ATOM 5822 O O . ALA A 1 735 ? 15.687 74.551 -17.430 1.00 16.12 ? 735 ALA A O 1 ATOM 5823 C CB . ALA A 1 735 ? 18.529 73.824 -15.916 1.00 12.98 ? 735 ALA A CB 1 ATOM 5824 N N . SER A 1 736 ? 16.647 76.346 -16.524 1.00 17.25 ? 736 SER A N 1 ATOM 5825 C CA . SER A 1 736 ? 16.062 77.293 -17.494 1.00 18.99 ? 736 SER A CA 1 ATOM 5826 C C . SER A 1 736 ? 17.199 77.799 -18.387 1.00 19.96 ? 736 SER A C 1 ATOM 5827 O O . SER A 1 736 ? 18.312 77.965 -17.911 1.00 19.66 ? 736 SER A O 1 ATOM 5828 C CB . SER A 1 736 ? 15.473 78.466 -16.724 1.00 19.36 ? 736 SER A CB 1 ATOM 5829 O OG . SER A 1 736 ? 14.628 78.006 -15.664 1.00 24.71 ? 736 SER A OG 1 ATOM 5830 N N . PRO A 1 737 ? 16.932 78.079 -19.673 1.00 21.81 ? 737 PRO A N 1 ATOM 5831 C CA . PRO A 1 737 ? 17.973 78.570 -20.600 1.00 22.76 ? 737 PRO A CA 1 ATOM 5832 C C . PRO A 1 737 ? 18.606 79.882 -20.163 1.00 22.81 ? 737 PRO A C 1 ATOM 5833 O O . PRO A 1 737 ? 17.914 80.769 -19.677 1.00 24.03 ? 737 PRO A O 1 ATOM 5834 C CB . PRO A 1 737 ? 17.226 78.744 -21.928 1.00 24.17 ? 737 PRO A CB 1 ATOM 5835 C CG . PRO A 1 737 ? 16.142 77.711 -21.858 1.00 23.57 ? 737 PRO A CG 1 ATOM 5836 C CD . PRO A 1 737 ? 15.664 77.832 -20.390 1.00 23.65 ? 737 PRO A CD 1 ATOM 5837 N N . VAL A 1 738 ? 19.934 79.976 -20.249 1.00 23.66 ? 738 VAL A N 1 ATOM 5838 C CA . VAL A 1 738 ? 20.622 81.237 -19.936 1.00 24.46 ? 738 VAL A CA 1 ATOM 5839 C C . VAL A 1 738 ? 20.254 82.199 -21.096 1.00 24.88 ? 738 VAL A C 1 ATOM 5840 O O . VAL A 1 738 ? 20.355 81.833 -22.270 1.00 24.78 ? 738 VAL A O 1 ATOM 5841 C CB . VAL A 1 738 ? 22.171 81.054 -19.910 1.00 24.02 ? 738 VAL A CB 1 ATOM 5842 C CG1 . VAL A 1 738 ? 22.873 82.440 -19.952 1.00 23.62 ? 738 VAL A CG1 1 ATOM 5843 C CG2 . VAL A 1 738 ? 22.606 80.273 -18.611 1.00 23.26 ? 738 VAL A CG2 1 ATOM 5844 N N . GLU A 1 739 ? 19.758 83.391 -20.792 1.00 25.83 ? 739 GLU A N 1 ATOM 5845 C CA . GLU A 1 739 ? 19.426 84.330 -21.864 1.00 27.47 ? 739 GLU A CA 1 ATOM 5846 C C . GLU A 1 739 ? 20.762 84.855 -22.402 1.00 26.35 ? 739 GLU A C 1 ATOM 5847 O O . GLU A 1 739 ? 21.502 85.519 -21.684 1.00 23.90 ? 739 GLU A O 1 ATOM 5848 C CB . GLU A 1 739 ? 18.547 85.459 -21.326 1.00 30.53 ? 739 GLU A CB 1 ATOM 5849 C CG . GLU A 1 739 ? 18.640 86.782 -22.109 1.00 35.11 ? 739 GLU A CG 1 ATOM 5850 C CD . GLU A 1 739 ? 17.387 87.657 -22.007 1.00 37.58 ? 739 GLU A CD 1 ATOM 5851 O OE1 . GLU A 1 739 ? 16.255 87.103 -21.856 1.00 38.04 ? 739 GLU A OE1 1 ATOM 5852 O OE2 . GLU A 1 739 ? 17.540 88.902 -22.106 1.00 38.57 ? 739 GLU A OE2 1 ATOM 5853 N N . LEU A 1 740 ? 21.034 84.551 -23.673 1.00 26.43 ? 740 LEU A N 1 ATOM 5854 C CA . LEU A 1 740 ? 22.308 84.898 -24.331 1.00 27.00 ? 740 LEU A CA 1 ATOM 5855 C C . LEU A 1 740 ? 22.478 86.250 -25.010 1.00 27.59 ? 740 LEU A C 1 ATOM 5856 O O . LEU A 1 740 ? 23.605 86.617 -25.329 1.00 27.20 ? 740 LEU A O 1 ATOM 5857 C CB . LEU A 1 740 ? 22.672 83.817 -25.354 1.00 26.26 ? 740 LEU A CB 1 ATOM 5858 C CG . LEU A 1 740 ? 22.653 82.377 -24.821 1.00 25.75 ? 740 LEU A CG 1 ATOM 5859 C CD1 . LEU A 1 740 ? 23.220 81.447 -25.885 1.00 26.51 ? 740 LEU A CD1 1 ATOM 5860 C CD2 . LEU A 1 740 ? 23.489 82.271 -23.547 1.00 25.88 ? 740 LEU A CD2 1 ATOM 5861 N N . GLY A 1 741 ? 21.382 86.971 -25.245 1.00 26.93 ? 741 GLY A N 1 ATOM 5862 C CA . GLY A 1 741 ? 21.474 88.266 -25.905 1.00 27.32 ? 741 GLY A CA 1 ATOM 5863 C C . GLY A 1 741 ? 22.038 88.047 -27.301 1.00 26.93 ? 741 GLY A C 1 ATOM 5864 O O . GLY A 1 741 ? 21.699 87.054 -27.940 1.00 26.59 ? 741 GLY A O 1 ATOM 5865 N N . GLN A 1 742 ? 22.869 88.969 -27.784 1.00 27.60 ? 742 GLN A N 1 ATOM 5866 C CA . GLN A 1 742 ? 23.503 88.823 -29.108 1.00 28.36 ? 742 GLN A CA 1 ATOM 5867 C C . GLN A 1 742 ? 24.992 88.759 -28.764 1.00 25.80 ? 742 GLN A C 1 ATOM 5868 O O . GLN A 1 742 ? 25.677 89.762 -28.695 1.00 26.71 ? 742 GLN A O 1 ATOM 5869 C CB . GLN A 1 742 ? 23.211 90.029 -29.999 1.00 30.84 ? 742 GLN A CB 1 ATOM 5870 C CG . GLN A 1 742 ? 23.441 89.722 -31.473 1.00 36.35 ? 742 GLN A CG 1 ATOM 5871 C CD . GLN A 1 742 ? 22.521 90.517 -32.422 1.00 40.00 ? 742 GLN A CD 1 ATOM 5872 O OE1 . GLN A 1 742 ? 22.626 90.378 -33.655 1.00 41.89 ? 742 GLN A OE1 1 ATOM 5873 N NE2 . GLN A 1 742 ? 21.613 91.344 -31.854 1.00 40.02 ? 742 GLN A NE2 1 ATOM 5874 N N . PRO A 1 743 ? 25.499 87.558 -28.497 1.00 23.83 ? 743 PRO A N 1 ATOM 5875 C CA . PRO A 1 743 ? 26.920 87.471 -28.137 1.00 22.28 ? 743 PRO A CA 1 ATOM 5876 C C . PRO A 1 743 ? 27.984 87.754 -29.176 1.00 20.27 ? 743 PRO A C 1 ATOM 5877 O O . PRO A 1 743 ? 27.776 87.561 -30.345 1.00 21.29 ? 743 PRO A O 1 ATOM 5878 C CB . PRO A 1 743 ? 27.044 86.047 -27.591 1.00 20.64 ? 743 PRO A CB 1 ATOM 5879 C CG . PRO A 1 743 ? 26.032 85.284 -28.405 1.00 23.05 ? 743 PRO A CG 1 ATOM 5880 C CD . PRO A 1 743 ? 24.843 86.231 -28.463 1.00 23.49 ? 743 PRO A CD 1 ATOM 5881 N N . VAL A 1 744 ? 29.146 88.194 -28.712 1.00 18.60 ? 744 VAL A N 1 ATOM 5882 C CA . VAL A 1 744 ? 30.269 88.437 -29.581 1.00 15.35 ? 744 VAL A CA 1 ATOM 5883 C C . VAL A 1 744 ? 30.995 87.094 -29.841 1.00 14.49 ? 744 VAL A C 1 ATOM 5884 O O . VAL A 1 744 ? 31.319 86.352 -28.890 1.00 15.22 ? 744 VAL A O 1 ATOM 5885 C CB . VAL A 1 744 ? 31.201 89.431 -28.960 1.00 15.78 ? 744 VAL A CB 1 ATOM 5886 C CG1 . VAL A 1 744 ? 32.474 89.532 -29.781 1.00 15.57 ? 744 VAL A CG1 1 ATOM 5887 C CG2 . VAL A 1 744 ? 30.475 90.787 -28.857 1.00 14.66 ? 744 VAL A CG2 1 ATOM 5888 N N . VAL A 1 745 ? 31.209 86.768 -31.110 1.00 12.62 ? 745 VAL A N 1 ATOM 5889 C CA . VAL A 1 745 ? 31.832 85.503 -31.513 1.00 12.35 ? 745 VAL A CA 1 ATOM 5890 C C . VAL A 1 745 ? 33.122 85.750 -32.253 1.00 13.78 ? 745 VAL A C 1 ATOM 5891 O O . VAL A 1 745 ? 33.170 86.590 -33.145 1.00 14.43 ? 745 VAL A O 1 ATOM 5892 C CB . VAL A 1 745 ? 30.862 84.634 -32.479 1.00 11.38 ? 745 VAL A CB 1 ATOM 5893 C CG1 . VAL A 1 745 ? 31.524 83.320 -32.887 1.00 12.80 ? 745 VAL A CG1 1 ATOM 5894 C CG2 . VAL A 1 745 ? 29.505 84.424 -31.835 1.00 10.29 ? 745 VAL A CG2 1 ATOM 5895 N N . LEU A 1 746 ? 34.199 85.073 -31.854 1.00 12.99 ? 746 LEU A N 1 ATOM 5896 C CA . LEU A 1 746 ? 35.499 85.195 -32.480 1.00 12.04 ? 746 LEU A CA 1 ATOM 5897 C C . LEU A 1 746 ? 35.928 83.871 -33.134 1.00 14.27 ? 746 LEU A C 1 ATOM 5898 O O . LEU A 1 746 ? 36.022 82.823 -32.450 1.00 14.19 ? 746 LEU A O 1 ATOM 5899 C CB . LEU A 1 746 ? 36.501 85.654 -31.389 1.00 13.69 ? 746 LEU A CB 1 ATOM 5900 C CG . LEU A 1 746 ? 37.975 85.693 -31.828 1.00 14.60 ? 746 LEU A CG 1 ATOM 5901 C CD1 . LEU A 1 746 ? 38.230 86.695 -32.992 1.00 19.48 ? 746 LEU A CD1 1 ATOM 5902 C CD2 . LEU A 1 746 ? 38.811 86.163 -30.623 1.00 18.79 ? 746 LEU A CD2 1 ATOM 5903 N N . VAL A 1 747 ? 36.208 83.899 -34.442 1.00 13.15 ? 747 VAL A N 1 ATOM 5904 C CA . VAL A 1 747 ? 36.612 82.732 -35.200 1.00 13.27 ? 747 VAL A CA 1 ATOM 5905 C C . VAL A 1 747 ? 38.037 82.918 -35.629 1.00 13.85 ? 747 VAL A C 1 ATOM 5906 O O . VAL A 1 747 ? 38.389 83.953 -36.241 1.00 15.37 ? 747 VAL A O 1 ATOM 5907 C CB . VAL A 1 747 ? 35.732 82.520 -36.484 1.00 12.19 ? 747 VAL A CB 1 ATOM 5908 C CG1 . VAL A 1 747 ? 36.086 81.237 -37.108 1.00 15.51 ? 747 VAL A CG1 1 ATOM 5909 C CG2 . VAL A 1 747 ? 34.239 82.576 -36.083 1.00 14.05 ? 747 VAL A CG2 1 ATOM 5910 N N . THR A 1 748 ? 38.900 81.972 -35.301 1.00 13.49 ? 748 THR A N 1 ATOM 5911 C CA . THR A 1 748 ? 40.316 82.065 -35.651 1.00 13.85 ? 748 THR A CA 1 ATOM 5912 C C . THR A 1 748 ? 40.539 80.834 -36.462 1.00 14.00 ? 748 THR A C 1 ATOM 5913 O O . THR A 1 748 ? 40.281 79.731 -35.984 1.00 16.22 ? 748 THR A O 1 ATOM 5914 C CB . THR A 1 748 ? 41.187 82.042 -34.375 1.00 14.41 ? 748 THR A CB 1 ATOM 5915 O OG1 . THR A 1 748 ? 40.978 83.257 -33.688 1.00 13.84 ? 748 THR A OG1 1 ATOM 5916 C CG2 . THR A 1 748 ? 42.681 81.957 -34.704 1.00 17.89 ? 748 THR A CG2 1 ATOM 5917 N N . LYS A 1 749 ? 40.974 80.985 -37.716 1.00 14.96 ? 749 LYS A N 1 ATOM 5918 C CA . LYS A 1 749 ? 41.172 79.850 -38.600 1.00 16.03 ? 749 LYS A CA 1 ATOM 5919 C C . LYS A 1 749 ? 42.608 79.726 -38.993 1.00 16.86 ? 749 LYS A C 1 ATOM 5920 O O . LYS A 1 749 ? 43.211 80.643 -39.580 1.00 15.75 ? 749 LYS A O 1 ATOM 5921 C CB . LYS A 1 749 ? 40.292 79.988 -39.862 1.00 15.96 ? 749 LYS A CB 1 ATOM 5922 C CG . LYS A 1 749 ? 40.479 78.888 -40.869 1.00 21.89 ? 749 LYS A CG 1 ATOM 5923 C CD . LYS A 1 749 ? 39.367 78.985 -41.922 1.00 24.45 ? 749 LYS A CD 1 ATOM 5924 C CE . LYS A 1 749 ? 39.648 78.051 -43.045 1.00 26.17 ? 749 LYS A CE 1 ATOM 5925 N NZ . LYS A 1 749 ? 41.012 78.416 -43.560 1.00 27.95 ? 749 LYS A NZ 1 ATOM 5926 N N . GLY A 1 750 ? 43.160 78.565 -38.655 1.00 15.66 ? 750 GLY A N 1 ATOM 5927 C CA . GLY A 1 750 ? 44.542 78.287 -38.952 1.00 15.91 ? 750 GLY A CA 1 ATOM 5928 C C . GLY A 1 750 ? 44.748 76.941 -39.582 1.00 16.18 ? 750 GLY A C 1 ATOM 5929 O O . GLY A 1 750 ? 43.879 76.053 -39.584 1.00 15.95 ? 750 GLY A O 1 ATOM 5930 N N . LYS A 1 751 ? 45.954 76.764 -40.082 1.00 14.27 ? 751 LYS A N 1 ATOM 5931 C CA . LYS A 1 751 ? 46.294 75.531 -40.681 1.00 16.65 ? 751 LYS A CA 1 ATOM 5932 C C . LYS A 1 751 ? 46.372 74.383 -39.650 1.00 15.50 ? 751 LYS A C 1 ATOM 5933 O O . LYS A 1 751 ? 45.970 73.256 -39.913 1.00 16.82 ? 751 LYS A O 1 ATOM 5934 C CB . LYS A 1 751 ? 47.646 75.681 -41.356 1.00 18.45 ? 751 LYS A CB 1 ATOM 5935 C CG . LYS A 1 751 ? 48.021 74.471 -42.180 1.00 23.82 ? 751 LYS A CG 1 ATOM 5936 C CD . LYS A 1 751 ? 49.140 74.849 -43.133 1.00 28.13 ? 751 LYS A CD 1 ATOM 5937 C CE . LYS A 1 751 ? 49.507 73.686 -44.051 1.00 29.22 ? 751 LYS A CE 1 ATOM 5938 N NZ . LYS A 1 751 ? 49.756 72.434 -43.257 1.00 30.94 ? 751 LYS A NZ 1 ATOM 5939 N N . LEU A 1 752 ? 46.929 74.708 -38.492 1.00 16.42 ? 752 LEU A N 1 ATOM 5940 C CA . LEU A 1 752 ? 47.173 73.715 -37.417 1.00 16.11 ? 752 LEU A CA 1 ATOM 5941 C C . LEU A 1 752 ? 46.119 73.710 -36.346 1.00 15.70 ? 752 LEU A C 1 ATOM 5942 O O . LEU A 1 752 ? 45.799 72.667 -35.803 1.00 14.75 ? 752 LEU A O 1 ATOM 5943 C CB . LEU A 1 752 ? 48.506 73.990 -36.723 1.00 16.87 ? 752 LEU A CB 1 ATOM 5944 C CG . LEU A 1 752 ? 49.764 74.014 -37.609 1.00 18.97 ? 752 LEU A CG 1 ATOM 5945 C CD1 . LEU A 1 752 ? 51.051 74.202 -36.776 1.00 20.28 ? 752 LEU A CD1 1 ATOM 5946 C CD2 . LEU A 1 752 ? 49.805 72.716 -38.350 1.00 18.34 ? 752 LEU A CD2 1 ATOM 5947 N N . GLU A 1 753 ? 45.502 74.853 -36.111 1.00 14.37 ? 753 GLU A N 1 ATOM 5948 C CA . GLU A 1 753 ? 44.511 74.985 -35.056 1.00 15.34 ? 753 GLU A CA 1 ATOM 5949 C C . GLU A 1 753 ? 43.522 76.092 -35.394 1.00 14.30 ? 753 GLU A C 1 ATOM 5950 O O . GLU A 1 753 ? 43.931 77.186 -35.803 1.00 15.78 ? 753 GLU A O 1 ATOM 5951 C CB . GLU A 1 753 ? 45.221 75.374 -33.730 1.00 14.79 ? 753 GLU A CB 1 ATOM 5952 C CG . GLU A 1 753 ? 44.224 75.564 -32.527 1.00 20.13 ? 753 GLU A CG 1 ATOM 5953 C CD . GLU A 1 753 ? 44.864 75.922 -31.166 1.00 23.23 ? 753 GLU A CD 1 ATOM 5954 O OE1 . GLU A 1 753 ? 45.268 77.069 -30.973 1.00 25.05 ? 753 GLU A OE1 1 ATOM 5955 O OE2 . GLU A 1 753 ? 44.944 75.042 -30.282 1.00 26.80 ? 753 GLU A OE2 1 ATOM 5956 N N . SER A 1 754 ? 42.235 75.844 -35.166 1.00 13.60 ? 754 SER A N 1 ATOM 5957 C CA . SER A 1 754 ? 41.233 76.887 -35.367 1.00 13.55 ? 754 SER A CA 1 ATOM 5958 C C . SER A 1 754 ? 40.339 76.880 -34.152 1.00 14.37 ? 754 SER A C 1 ATOM 5959 O O . SER A 1 754 ? 40.337 75.898 -33.392 1.00 13.27 ? 754 SER A O 1 ATOM 5960 C CB . SER A 1 754 ? 40.368 76.604 -36.602 1.00 13.10 ? 754 SER A CB 1 ATOM 5961 O OG . SER A 1 754 ? 41.157 76.583 -37.778 1.00 13.21 ? 754 SER A OG 1 ATOM 5962 N N . SER A 1 755 ? 39.510 77.895 -34.003 1.00 12.63 ? 755 SER A N 1 ATOM 5963 C CA . SER A 1 755 ? 38.619 77.914 -32.843 1.00 13.64 ? 755 SER A CA 1 ATOM 5964 C C . SER A 1 755 ? 37.529 78.944 -32.985 1.00 14.35 ? 755 SER A C 1 ATOM 5965 O O . SER A 1 755 ? 37.639 79.888 -33.782 1.00 15.14 ? 755 SER A O 1 ATOM 5966 C CB . SER A 1 755 ? 39.388 78.252 -31.562 1.00 16.54 ? 755 SER A CB 1 ATOM 5967 O OG . SER A 1 755 ? 39.848 79.579 -31.649 1.00 17.27 ? 755 SER A OG 1 ATOM 5968 N N . VAL A 1 756 ? 36.457 78.707 -32.276 1.00 11.74 ? 756 VAL A N 1 ATOM 5969 C CA . VAL A 1 756 ? 35.332 79.622 -32.230 1.00 11.89 ? 756 VAL A CA 1 ATOM 5970 C C . VAL A 1 756 ? 35.172 79.875 -30.717 1.00 13.15 ? 756 VAL A C 1 ATOM 5971 O O . VAL A 1 756 ? 35.029 78.936 -29.909 1.00 13.42 ? 756 VAL A O 1 ATOM 5972 C CB . VAL A 1 756 ? 34.019 78.972 -32.769 1.00 11.85 ? 756 VAL A CB 1 ATOM 5973 C CG1 . VAL A 1 756 ? 32.832 79.913 -32.468 1.00 10.49 ? 756 VAL A CG1 1 ATOM 5974 C CG2 . VAL A 1 756 ? 34.136 78.582 -34.245 1.00 14.15 ? 756 VAL A CG2 1 ATOM 5975 N N . SER A 1 757 ? 35.170 81.131 -30.330 1.00 11.63 ? 757 SER A N 1 ATOM 5976 C CA . SER A 1 757 ? 35.026 81.537 -28.959 1.00 12.32 ? 757 SER A CA 1 ATOM 5977 C C . SER A 1 757 ? 33.890 82.487 -28.812 1.00 13.48 ? 757 SER A C 1 ATOM 5978 O O . SER A 1 757 ? 33.754 83.397 -29.619 1.00 13.57 ? 757 SER A O 1 ATOM 5979 C CB . SER A 1 757 ? 36.318 82.228 -28.452 1.00 13.19 ? 757 SER A CB 1 ATOM 5980 O OG . SER A 1 757 ? 37.414 81.289 -28.610 1.00 15.57 ? 757 SER A OG 1 ATOM 5981 N N . VAL A 1 758 ? 33.076 82.340 -27.792 1.00 13.25 ? 758 VAL A N 1 ATOM 5982 C CA . VAL A 1 758 ? 31.940 83.265 -27.636 1.00 12.45 ? 758 VAL A CA 1 ATOM 5983 C C . VAL A 1 758 ? 31.843 83.766 -26.221 1.00 13.91 ? 758 VAL A C 1 ATOM 5984 O O . VAL A 1 758 ? 32.014 83.000 -25.245 1.00 14.40 ? 758 VAL A O 1 ATOM 5985 C CB . VAL A 1 758 ? 30.578 82.635 -28.021 1.00 14.16 ? 758 VAL A CB 1 ATOM 5986 C CG1 . VAL A 1 758 ? 30.314 81.320 -27.223 1.00 15.48 ? 758 VAL A CG1 1 ATOM 5987 C CG2 . VAL A 1 758 ? 29.449 83.657 -27.743 1.00 14.96 ? 758 VAL A CG2 1 ATOM 5988 N N . GLY A 1 759 ? 31.560 85.049 -26.076 1.00 14.58 ? 759 GLY A N 1 ATOM 5989 C CA . GLY A 1 759 ? 31.416 85.648 -24.760 1.00 12.46 ? 759 GLY A CA 1 ATOM 5990 C C . GLY A 1 759 ? 29.971 85.573 -24.312 1.00 13.98 ? 759 GLY A C 1 ATOM 5991 O O . GLY A 1 759 ? 29.123 86.304 -24.776 1.00 12.90 ? 759 GLY A O 1 ATOM 5992 N N . LEU A 1 760 ? 29.662 84.639 -23.424 1.00 13.58 ? 760 LEU A N 1 ATOM 5993 C CA . LEU A 1 760 ? 28.294 84.433 -22.910 1.00 13.97 ? 760 LEU A CA 1 ATOM 5994 C C . LEU A 1 760 ? 28.237 84.958 -21.500 1.00 13.92 ? 760 LEU A C 1 ATOM 5995 O O . LEU A 1 760 ? 29.280 85.194 -20.873 1.00 16.65 ? 760 LEU A O 1 ATOM 5996 C CB . LEU A 1 760 ? 27.938 82.922 -22.872 1.00 14.06 ? 760 LEU A CB 1 ATOM 5997 C CG . LEU A 1 760 ? 28.050 82.110 -24.189 1.00 12.67 ? 760 LEU A CG 1 ATOM 5998 C CD1 . LEU A 1 760 ? 27.662 80.655 -24.010 1.00 17.35 ? 760 LEU A CD1 1 ATOM 5999 C CD2 . LEU A 1 760 ? 27.154 82.773 -25.282 1.00 16.30 ? 760 LEU A CD2 1 ATOM 6000 N N . PRO A 1 761 ? 27.029 85.169 -20.955 1.00 15.09 ? 761 PRO A N 1 ATOM 6001 C CA . PRO A 1 761 ? 26.982 85.667 -19.562 1.00 15.56 ? 761 PRO A CA 1 ATOM 6002 C C . PRO A 1 761 ? 27.553 84.536 -18.644 1.00 17.49 ? 761 PRO A C 1 ATOM 6003 O O . PRO A 1 761 ? 27.105 83.361 -18.726 1.00 18.78 ? 761 PRO A O 1 ATOM 6004 C CB . PRO A 1 761 ? 25.493 85.894 -19.316 1.00 16.36 ? 761 PRO A CB 1 ATOM 6005 C CG . PRO A 1 761 ? 24.905 86.062 -20.698 1.00 15.94 ? 761 PRO A CG 1 ATOM 6006 C CD . PRO A 1 761 ? 25.693 85.148 -21.595 1.00 13.39 ? 761 PRO A CD 1 ATOM 6007 N N . SER A 1 762 ? 28.551 84.880 -17.841 1.00 15.52 ? 762 SER A N 1 ATOM 6008 C CA . SER A 1 762 ? 29.241 83.909 -16.937 1.00 15.60 ? 762 SER A CA 1 ATOM 6009 C C . SER A 1 762 ? 30.185 82.922 -17.559 1.00 13.31 ? 762 SER A C 1 ATOM 6010 O O . SER A 1 762 ? 30.827 82.157 -16.834 1.00 14.43 ? 762 SER A O 1 ATOM 6011 C CB . SER A 1 762 ? 28.251 83.073 -16.148 1.00 14.18 ? 762 SER A CB 1 ATOM 6012 O OG . SER A 1 762 ? 27.458 83.878 -15.333 1.00 17.83 ? 762 SER A OG 1 ATOM 6013 N N . VAL A 1 763 ? 30.302 82.884 -18.883 1.00 12.43 ? 763 VAL A N 1 ATOM 6014 C CA . VAL A 1 763 ? 31.188 81.907 -19.517 1.00 12.27 ? 763 VAL A CA 1 ATOM 6015 C C . VAL A 1 763 ? 31.746 82.305 -20.858 1.00 12.94 ? 763 VAL A C 1 ATOM 6016 O O . VAL A 1 763 ? 30.960 82.582 -21.756 1.00 13.81 ? 763 VAL A O 1 ATOM 6017 C CB . VAL A 1 763 ? 30.417 80.569 -19.779 1.00 13.27 ? 763 VAL A CB 1 ATOM 6018 C CG1 . VAL A 1 763 ? 31.347 79.473 -20.296 1.00 12.79 ? 763 VAL A CG1 1 ATOM 6019 C CG2 . VAL A 1 763 ? 29.735 80.105 -18.489 1.00 14.79 ? 763 VAL A CG2 1 ATOM 6020 N N . VAL A 1 764 ? 33.066 82.291 -21.010 1.00 10.74 ? 764 VAL A N 1 ATOM 6021 C CA . VAL A 1 764 ? 33.671 82.477 -22.328 1.00 11.53 ? 764 VAL A CA 1 ATOM 6022 C C . VAL A 1 764 ? 33.841 81.021 -22.737 1.00 12.02 ? 764 VAL A C 1 ATOM 6023 O O . VAL A 1 764 ? 34.678 80.248 -22.165 1.00 10.68 ? 764 VAL A O 1 ATOM 6024 C CB . VAL A 1 764 ? 35.030 83.267 -22.313 1.00 11.52 ? 764 VAL A CB 1 ATOM 6025 C CG1 . VAL A 1 764 ? 35.617 83.279 -23.730 1.00 11.91 ? 764 VAL A CG1 1 ATOM 6026 C CG2 . VAL A 1 764 ? 34.827 84.673 -21.793 1.00 11.76 ? 764 VAL A CG2 1 ATOM 6027 N N . HIS A 1 765 ? 33.034 80.590 -23.719 1.00 13.24 ? 765 HIS A N 1 ATOM 6028 C CA . HIS A 1 765 ? 32.988 79.210 -24.230 1.00 12.14 ? 765 HIS A CA 1 ATOM 6029 C C . HIS A 1 765 ? 33.818 79.107 -25.499 1.00 14.33 ? 765 HIS A C 1 ATOM 6030 O O . HIS A 1 765 ? 33.560 79.868 -26.448 1.00 13.21 ? 765 HIS A O 1 ATOM 6031 C CB . HIS A 1 765 ? 31.509 78.874 -24.520 1.00 12.90 ? 765 HIS A CB 1 ATOM 6032 C CG . HIS A 1 765 ? 31.261 77.578 -25.207 1.00 12.92 ? 765 HIS A CG 1 ATOM 6033 N ND1 . HIS A 1 765 ? 31.419 76.353 -24.583 1.00 12.78 ? 765 HIS A ND1 1 ATOM 6034 C CD2 . HIS A 1 765 ? 30.761 77.316 -26.445 1.00 12.32 ? 765 HIS A CD2 1 ATOM 6035 C CE1 . HIS A 1 765 ? 31.022 75.396 -25.413 1.00 13.88 ? 765 HIS A CE1 1 ATOM 6036 N NE2 . HIS A 1 765 ? 30.616 75.954 -26.549 1.00 13.00 ? 765 HIS A NE2 1 ATOM 6037 N N . GLN A 1 766 ? 34.731 78.148 -25.573 1.00 13.40 ? 766 GLN A N 1 ATOM 6038 C CA . GLN A 1 766 ? 35.607 78.055 -26.719 1.00 13.53 ? 766 GLN A CA 1 ATOM 6039 C C . GLN A 1 766 ? 35.655 76.632 -27.238 1.00 13.57 ? 766 GLN A C 1 ATOM 6040 O O . GLN A 1 766 ? 35.744 75.664 -26.416 1.00 10.96 ? 766 GLN A O 1 ATOM 6041 C CB . GLN A 1 766 ? 37.010 78.482 -26.294 1.00 16.00 ? 766 GLN A CB 1 ATOM 6042 C CG . GLN A 1 766 ? 37.009 79.718 -25.428 1.00 21.13 ? 766 GLN A CG 1 ATOM 6043 C CD . GLN A 1 766 ? 38.214 79.819 -24.475 1.00 24.68 ? 766 GLN A CD 1 ATOM 6044 O OE1 . GLN A 1 766 ? 39.356 79.448 -24.841 1.00 26.76 ? 766 GLN A OE1 1 ATOM 6045 N NE2 . GLN A 1 766 ? 37.960 80.339 -23.231 1.00 25.62 ? 766 GLN A NE2 1 ATOM 6046 N N . THR A 1 767 ? 35.547 76.459 -28.565 1.00 12.39 ? 767 THR A N 1 ATOM 6047 C CA . THR A 1 767 ? 35.651 75.162 -29.173 1.00 12.54 ? 767 THR A CA 1 ATOM 6048 C C . THR A 1 767 ? 36.918 75.198 -30.045 1.00 13.48 ? 767 THR A C 1 ATOM 6049 O O . THR A 1 767 ? 36.988 75.996 -30.996 1.00 14.01 ? 767 THR A O 1 ATOM 6050 C CB . THR A 1 767 ? 34.431 74.835 -30.078 1.00 11.15 ? 767 THR A CB 1 ATOM 6051 O OG1 . THR A 1 767 ? 33.234 74.882 -29.302 1.00 13.94 ? 767 THR A OG1 1 ATOM 6052 C CG2 . THR A 1 767 ? 34.590 73.522 -30.714 1.00 12.22 ? 767 THR A CG2 1 ATOM 6053 N N . ILE A 1 768 ? 37.911 74.359 -29.746 1.00 11.99 ? 768 ILE A N 1 ATOM 6054 C CA . ILE A 1 768 ? 39.188 74.314 -30.483 1.00 12.96 ? 768 ILE A CA 1 ATOM 6055 C C . ILE A 1 768 ? 39.312 73.082 -31.320 1.00 12.79 ? 768 ILE A C 1 ATOM 6056 O O . ILE A 1 768 ? 38.936 71.987 -30.843 1.00 13.80 ? 768 ILE A O 1 ATOM 6057 C CB . ILE A 1 768 ? 40.326 74.389 -29.502 1.00 11.92 ? 768 ILE A CB 1 ATOM 6058 C CG1 . ILE A 1 768 ? 40.057 75.566 -28.593 1.00 11.67 ? 768 ILE A CG1 1 ATOM 6059 C CG2 . ILE A 1 768 ? 41.628 74.640 -30.216 1.00 12.83 ? 768 ILE A CG2 1 ATOM 6060 C CD1 . ILE A 1 768 ? 40.983 75.671 -27.346 1.00 16.23 ? 768 ILE A CD1 1 ATOM 6061 N N . MET A 1 769 ? 39.804 73.225 -32.559 1.00 12.97 ? 769 MET A N 1 ATOM 6062 C CA . MET A 1 769 ? 39.953 72.135 -33.520 1.00 14.84 ? 769 MET A CA 1 ATOM 6063 C C . MET A 1 769 ? 41.394 72.013 -33.962 1.00 14.77 ? 769 MET A C 1 ATOM 6064 O O . MET A 1 769 ? 42.035 72.998 -34.375 1.00 14.75 ? 769 MET A O 1 ATOM 6065 C CB . MET A 1 769 ? 39.066 72.386 -34.743 1.00 14.35 ? 769 MET A CB 1 ATOM 6066 C CG . MET A 1 769 ? 37.594 72.302 -34.429 1.00 14.58 ? 769 MET A CG 1 ATOM 6067 S SD A MET A 1 769 ? 36.600 73.424 -35.465 0.50 15.48 ? 769 MET A SD 1 ATOM 6068 S SD B MET A 1 769 ? 36.617 72.839 -35.725 0.50 15.43 ? 769 MET A SD 1 ATOM 6069 C CE A MET A 1 769 ? 36.486 74.838 -34.431 0.50 13.12 ? 769 MET A CE 1 ATOM 6070 C CE B MET A 1 769 ? 36.919 71.422 -36.737 0.50 11.26 ? 769 MET A CE 1 ATOM 6071 N N . ARG A 1 770 ? 41.923 70.801 -33.841 1.00 14.59 ? 770 ARG A N 1 ATOM 6072 C CA . ARG A 1 770 ? 43.292 70.571 -34.233 1.00 15.18 ? 770 ARG A CA 1 ATOM 6073 C C . ARG A 1 770 ? 43.421 69.382 -35.160 1.00 15.47 ? 770 ARG A C 1 ATOM 6074 O O . ARG A 1 770 ? 44.519 68.899 -35.387 1.00 15.71 ? 770 ARG A O 1 ATOM 6075 C CB . ARG A 1 770 ? 44.196 70.447 -32.979 1.00 17.26 ? 770 ARG A CB 1 ATOM 6076 C CG . ARG A 1 770 ? 44.268 71.768 -32.159 1.00 19.71 ? 770 ARG A CG 1 ATOM 6077 C CD . ARG A 1 770 ? 45.124 71.742 -30.865 1.00 22.76 ? 770 ARG A CD 1 ATOM 6078 N NE . ARG A 1 770 ? 44.314 71.607 -29.655 1.00 27.48 ? 770 ARG A NE 1 ATOM 6079 C CZ . ARG A 1 770 ? 44.389 70.548 -28.861 1.00 29.31 ? 770 ARG A CZ 1 ATOM 6080 N NH1 . ARG A 1 770 ? 45.239 69.579 -29.178 1.00 30.37 ? 770 ARG A NH1 1 ATOM 6081 N NH2 . ARG A 1 770 ? 43.627 70.441 -27.775 1.00 30.82 ? 770 ARG A NH2 1 ATOM 6082 N N . GLY A 1 771 ? 42.293 68.943 -35.735 1.00 15.39 ? 771 GLY A N 1 ATOM 6083 C CA . GLY A 1 771 ? 42.312 67.830 -36.647 1.00 17.89 ? 771 GLY A CA 1 ATOM 6084 C C . GLY A 1 771 ? 41.603 66.575 -36.225 1.00 18.34 ? 771 GLY A C 1 ATOM 6085 O O . GLY A 1 771 ? 41.391 65.695 -37.077 1.00 19.42 ? 771 GLY A O 1 ATOM 6086 N N . GLY A 1 772 ? 41.259 66.482 -34.936 1.00 17.90 ? 772 GLY A N 1 ATOM 6087 C CA . GLY A 1 772 ? 40.533 65.332 -34.398 1.00 16.75 ? 772 GLY A CA 1 ATOM 6088 C C . GLY A 1 772 ? 39.383 65.832 -33.521 1.00 17.24 ? 772 GLY A C 1 ATOM 6089 O O . GLY A 1 772 ? 38.709 66.825 -33.875 1.00 16.80 ? 772 GLY A O 1 ATOM 6090 N N . ALA A 1 773 ? 39.109 65.163 -32.397 1.00 16.76 ? 773 ALA A N 1 ATOM 6091 C CA . ALA A 1 773 ? 38.011 65.591 -31.519 1.00 15.74 ? 773 ALA A CA 1 ATOM 6092 C C . ALA A 1 773 ? 38.262 66.977 -31.056 1.00 13.97 ? 773 ALA A C 1 ATOM 6093 O O . ALA A 1 773 ? 39.366 67.309 -30.721 1.00 13.20 ? 773 ALA A O 1 ATOM 6094 C CB . ALA A 1 773 ? 37.906 64.685 -30.322 1.00 17.37 ? 773 ALA A CB 1 ATOM 6095 N N . PRO A 1 774 ? 37.235 67.825 -31.025 1.00 13.75 ? 774 PRO A N 1 ATOM 6096 C CA . PRO A 1 774 ? 37.524 69.163 -30.556 1.00 13.48 ? 774 PRO A CA 1 ATOM 6097 C C . PRO A 1 774 ? 37.825 69.234 -29.044 1.00 13.01 ? 774 PRO A C 1 ATOM 6098 O O . PRO A 1 774 ? 37.493 68.297 -28.271 1.00 13.17 ? 774 PRO A O 1 ATOM 6099 C CB . PRO A 1 774 ? 36.259 69.957 -30.899 1.00 13.60 ? 774 PRO A CB 1 ATOM 6100 C CG . PRO A 1 774 ? 35.236 68.949 -30.848 1.00 15.17 ? 774 PRO A CG 1 ATOM 6101 C CD . PRO A 1 774 ? 35.864 67.747 -31.558 1.00 13.28 ? 774 PRO A CD 1 ATOM 6102 N N . GLU A 1 775 ? 38.439 70.325 -28.658 1.00 13.70 ? 775 GLU A N 1 ATOM 6103 C CA . GLU A 1 775 ? 38.665 70.583 -27.266 1.00 11.86 ? 775 GLU A CA 1 ATOM 6104 C C . GLU A 1 775 ? 37.713 71.699 -26.903 1.00 13.01 ? 775 GLU A C 1 ATOM 6105 O O . GLU A 1 775 ? 37.472 72.603 -27.725 1.00 14.05 ? 775 GLU A O 1 ATOM 6106 C CB . GLU A 1 775 ? 40.119 71.003 -27.003 1.00 13.22 ? 775 GLU A CB 1 ATOM 6107 C CG . GLU A 1 775 ? 40.351 71.482 -25.562 1.00 10.24 ? 775 GLU A CG 1 ATOM 6108 C CD . GLU A 1 775 ? 41.760 71.918 -25.238 1.00 15.94 ? 775 GLU A CD 1 ATOM 6109 O OE1 . GLU A 1 775 ? 42.608 71.912 -26.151 1.00 17.15 ? 775 GLU A OE1 1 ATOM 6110 O OE2 . GLU A 1 775 ? 42.038 72.273 -24.077 1.00 15.05 ? 775 GLU A OE2 1 ATOM 6111 N N . ILE A 1 776 ? 37.109 71.632 -25.715 1.00 11.47 ? 776 ILE A N 1 ATOM 6112 C CA . ILE A 1 776 ? 36.251 72.693 -25.228 1.00 11.93 ? 776 ILE A CA 1 ATOM 6113 C C . ILE A 1 776 ? 36.880 73.341 -24.040 1.00 12.85 ? 776 ILE A C 1 ATOM 6114 O O . ILE A 1 776 ? 37.380 72.644 -23.139 1.00 12.09 ? 776 ILE A O 1 ATOM 6115 C CB . ILE A 1 776 ? 34.869 72.192 -24.762 1.00 11.73 ? 776 ILE A CB 1 ATOM 6116 C CG1 . ILE A 1 776 ? 34.257 71.263 -25.847 1.00 14.45 ? 776 ILE A CG1 1 ATOM 6117 C CG2 . ILE A 1 776 ? 34.005 73.342 -24.385 1.00 12.68 ? 776 ILE A CG2 1 ATOM 6118 C CD1 . ILE A 1 776 ? 34.206 71.814 -27.326 1.00 16.16 ? 776 ILE A CD1 1 ATOM 6119 N N . ARG A 1 777 ? 36.891 74.658 -24.011 1.00 10.85 ? 777 ARG A N 1 ATOM 6120 C CA . ARG A 1 777 ? 37.376 75.365 -22.849 1.00 10.47 ? 777 ARG A CA 1 ATOM 6121 C C . ARG A 1 777 ? 36.353 76.356 -22.377 1.00 12.51 ? 777 ARG A C 1 ATOM 6122 O O . ARG A 1 777 ? 35.834 77.144 -23.234 1.00 11.37 ? 777 ARG A O 1 ATOM 6123 C CB . ARG A 1 777 ? 38.691 76.121 -23.075 1.00 12.92 ? 777 ARG A CB 1 ATOM 6124 C CG . ARG A 1 777 ? 39.858 75.271 -23.489 1.00 12.08 ? 777 ARG A CG 1 ATOM 6125 C CD . ARG A 1 777 ? 41.204 76.041 -23.506 1.00 14.51 ? 777 ARG A CD 1 ATOM 6126 N NE . ARG A 1 777 ? 42.252 75.150 -24.021 1.00 14.28 ? 777 ARG A NE 1 ATOM 6127 C CZ . ARG A 1 777 ? 43.414 75.549 -24.541 1.00 16.95 ? 777 ARG A CZ 1 ATOM 6128 N NH1 . ARG A 1 777 ? 43.714 76.836 -24.599 1.00 18.21 ? 777 ARG A NH1 1 ATOM 6129 N NH2 . ARG A 1 777 ? 44.231 74.663 -25.093 1.00 18.99 ? 777 ARG A NH2 1 ATOM 6130 N N . ASN A 1 778 ? 36.002 76.350 -21.077 1.00 9.44 ? 778 ASN A N 1 ATOM 6131 C CA . ASN A 1 778 ? 35.035 77.319 -20.532 1.00 10.80 ? 778 ASN A CA 1 ATOM 6132 C C . ASN A 1 778 ? 35.674 78.140 -19.426 1.00 11.66 ? 778 ASN A C 1 ATOM 6133 O O . ASN A 1 778 ? 36.172 77.572 -18.406 1.00 11.87 ? 778 ASN A O 1 ATOM 6134 C CB . ASN A 1 778 ? 33.730 76.707 -19.888 1.00 11.01 ? 778 ASN A CB 1 ATOM 6135 C CG . ASN A 1 778 ? 32.837 75.957 -20.867 1.00 12.32 ? 778 ASN A CG 1 ATOM 6136 O OD1 . ASN A 1 778 ? 32.849 76.188 -22.085 1.00 11.88 ? 778 ASN A OD1 1 ATOM 6137 N ND2 . ASN A 1 778 ? 32.064 75.009 -20.328 1.00 10.21 ? 778 ASN A ND2 1 ATOM 6138 N N . LEU A 1 779 ? 35.737 79.459 -19.609 1.00 11.88 ? 779 LEU A N 1 ATOM 6139 C CA . LEU A 1 779 ? 36.243 80.353 -18.557 1.00 11.50 ? 779 LEU A CA 1 ATOM 6140 C C . LEU A 1 779 ? 34.989 80.760 -17.852 1.00 12.94 ? 779 LEU A C 1 ATOM 6141 O O . LEU A 1 779 ? 34.194 81.593 -18.329 1.00 11.77 ? 779 LEU A O 1 ATOM 6142 C CB . LEU A 1 779 ? 36.988 81.591 -19.139 1.00 12.89 ? 779 LEU A CB 1 ATOM 6143 C CG . LEU A 1 779 ? 37.423 82.555 -18.007 1.00 14.75 ? 779 LEU A CG 1 ATOM 6144 C CD1 . LEU A 1 779 ? 38.435 81.959 -17.029 1.00 19.20 ? 779 LEU A CD1 1 ATOM 6145 C CD2 . LEU A 1 779 ? 37.923 83.887 -18.709 1.00 17.09 ? 779 LEU A CD2 1 ATOM 6146 N N . VAL A 1 780 ? 34.795 80.111 -16.705 1.00 10.86 ? 780 VAL A N 1 ATOM 6147 C CA . VAL A 1 780 ? 33.589 80.249 -15.894 1.00 11.50 ? 780 VAL A CA 1 ATOM 6148 C C . VAL A 1 780 ? 33.718 81.232 -14.755 1.00 11.18 ? 780 VAL A C 1 ATOM 6149 O O . VAL A 1 780 ? 34.515 81.084 -13.786 1.00 10.67 ? 780 VAL A O 1 ATOM 6150 C CB . VAL A 1 780 ? 33.039 78.818 -15.360 1.00 9.63 ? 780 VAL A CB 1 ATOM 6151 C CG1 . VAL A 1 780 ? 31.631 79.007 -14.754 1.00 12.36 ? 780 VAL A CG1 1 ATOM 6152 C CG2 . VAL A 1 780 ? 32.932 77.804 -16.517 1.00 10.90 ? 780 VAL A CG2 1 ATOM 6153 N N . ASP A 1 781 ? 32.960 82.336 -14.892 1.00 11.80 ? 781 ASP A N 1 ATOM 6154 C CA . ASP A 1 781 ? 32.929 83.312 -13.823 1.00 12.69 ? 781 ASP A CA 1 ATOM 6155 C C . ASP A 1 781 ? 31.503 83.598 -13.487 1.00 14.67 ? 781 ASP A C 1 ATOM 6156 O O . ASP A 1 781 ? 30.847 84.415 -14.184 1.00 14.65 ? 781 ASP A O 1 ATOM 6157 C CB . ASP A 1 781 ? 33.628 84.627 -14.207 1.00 14.80 ? 781 ASP A CB 1 ATOM 6158 C CG . ASP A 1 781 ? 33.713 85.630 -13.058 1.00 16.60 ? 781 ASP A CG 1 ATOM 6159 O OD1 . ASP A 1 781 ? 33.228 85.425 -11.938 1.00 17.02 ? 781 ASP A OD1 1 ATOM 6160 O OD2 . ASP A 1 781 ? 34.287 86.729 -13.279 1.00 20.61 ? 781 ASP A OD2 1 ATOM 6161 N N . ILE A 1 782 ? 31.012 82.963 -12.404 1.00 14.33 ? 782 ILE A N 1 ATOM 6162 C CA . ILE A 1 782 ? 29.605 83.090 -11.993 1.00 15.90 ? 782 ILE A CA 1 ATOM 6163 C C . ILE A 1 782 ? 29.331 84.412 -11.318 1.00 16.12 ? 782 ILE A C 1 ATOM 6164 O O . ILE A 1 782 ? 28.170 84.740 -11.089 1.00 17.30 ? 782 ILE A O 1 ATOM 6165 C CB . ILE A 1 782 ? 29.236 81.852 -11.120 1.00 15.22 ? 782 ILE A CB 1 ATOM 6166 C CG1 . ILE A 1 782 ? 27.724 81.611 -11.045 1.00 17.36 ? 782 ILE A CG1 1 ATOM 6167 C CG2 . ILE A 1 782 ? 29.857 81.990 -9.744 1.00 14.33 ? 782 ILE A CG2 1 ATOM 6168 C CD1 . ILE A 1 782 ? 27.434 80.200 -10.562 1.00 17.15 ? 782 ILE A CD1 1 ATOM 6169 N N . GLY A 1 783 ? 30.379 85.192 -11.065 1.00 16.92 ? 783 GLY A N 1 ATOM 6170 C CA . GLY A 1 783 ? 30.254 86.528 -10.490 1.00 18.26 ? 783 GLY A CA 1 ATOM 6171 C C . GLY A 1 783 ? 29.418 86.640 -9.254 1.00 19.54 ? 783 GLY A C 1 ATOM 6172 O O . GLY A 1 783 ? 29.680 85.951 -8.281 1.00 21.07 ? 783 GLY A O 1 ATOM 6173 N N . SER A 1 784 ? 28.422 87.520 -9.248 1.00 20.94 ? 784 SER A N 1 ATOM 6174 C CA . SER A 1 784 ? 27.591 87.666 -8.065 1.00 22.10 ? 784 SER A CA 1 ATOM 6175 C C . SER A 1 784 ? 26.209 87.061 -8.227 1.00 20.98 ? 784 SER A C 1 ATOM 6176 O O . SER A 1 784 ? 25.242 87.491 -7.585 1.00 20.83 ? 784 SER A O 1 ATOM 6177 C CB . SER A 1 784 ? 27.435 89.158 -7.697 1.00 24.28 ? 784 SER A CB 1 ATOM 6178 O OG . SER A 1 784 ? 26.846 89.899 -8.779 1.00 27.55 ? 784 SER A OG 1 ATOM 6179 N N . LEU A 1 785 ? 26.075 86.072 -9.094 1.00 21.17 ? 785 LEU A N 1 ATOM 6180 C CA . LEU A 1 785 ? 24.745 85.473 -9.279 1.00 21.67 ? 785 LEU A CA 1 ATOM 6181 C C . LEU A 1 785 ? 24.398 84.498 -8.167 1.00 21.56 ? 785 LEU A C 1 ATOM 6182 O O . LEU A 1 785 ? 24.590 83.268 -8.319 1.00 20.39 ? 785 LEU A O 1 ATOM 6183 C CB . LEU A 1 785 ? 24.706 84.735 -10.595 1.00 22.13 ? 785 LEU A CB 1 ATOM 6184 C CG . LEU A 1 785 ? 24.926 85.599 -11.827 1.00 24.68 ? 785 LEU A CG 1 ATOM 6185 C CD1 . LEU A 1 785 ? 25.114 84.694 -12.934 1.00 23.46 ? 785 LEU A CD1 1 ATOM 6186 C CD2 . LEU A 1 785 ? 23.759 86.524 -12.088 1.00 23.37 ? 785 LEU A CD2 1 ATOM 6187 N N . ASP A 1 786 ? 23.896 84.992 -7.044 1.00 21.62 ? 786 ASP A N 1 ATOM 6188 C CA . ASP A 1 786 ? 23.520 84.112 -5.920 1.00 21.94 ? 786 ASP A CA 1 ATOM 6189 C C . ASP A 1 786 ? 22.430 83.079 -6.272 1.00 20.13 ? 786 ASP A C 1 ATOM 6190 O O . ASP A 1 786 ? 21.559 83.331 -7.096 1.00 20.82 ? 786 ASP A O 1 ATOM 6191 C CB . ASP A 1 786 ? 23.017 84.949 -4.751 1.00 24.87 ? 786 ASP A CB 1 ATOM 6192 C CG . ASP A 1 786 ? 24.111 85.779 -4.117 1.00 28.25 ? 786 ASP A CG 1 ATOM 6193 O OD1 . ASP A 1 786 ? 25.254 85.775 -4.646 1.00 28.10 ? 786 ASP A OD1 1 ATOM 6194 O OD2 . ASP A 1 786 ? 23.819 86.449 -3.099 1.00 29.33 ? 786 ASP A OD2 1 ATOM 6195 N N . ASN A 1 787 ? 22.509 81.891 -5.679 1.00 18.63 ? 787 ASN A N 1 ATOM 6196 C CA . ASN A 1 787 ? 21.493 80.848 -5.895 1.00 17.34 ? 787 ASN A CA 1 ATOM 6197 C C . ASN A 1 787 ? 21.315 80.424 -7.323 1.00 17.14 ? 787 ASN A C 1 ATOM 6198 O O . ASN A 1 787 ? 20.205 80.268 -7.854 1.00 15.74 ? 787 ASN A O 1 ATOM 6199 C CB . ASN A 1 787 ? 20.171 81.306 -5.276 1.00 19.60 ? 787 ASN A CB 1 ATOM 6200 C CG . ASN A 1 787 ? 20.317 81.565 -3.786 1.00 21.61 ? 787 ASN A CG 1 ATOM 6201 O OD1 . ASN A 1 787 ? 21.019 80.825 -3.057 1.00 22.67 ? 787 ASN A OD1 1 ATOM 6202 N ND2 . ASN A 1 787 ? 19.661 82.632 -3.308 1.00 23.13 ? 787 ASN A ND2 1 ATOM 6203 N N . THR A 1 788 ? 22.447 80.198 -7.958 1.00 14.19 ? 788 THR A N 1 ATOM 6204 C CA . THR A 1 788 ? 22.472 79.830 -9.343 1.00 14.33 ? 788 THR A CA 1 ATOM 6205 C C . THR A 1 788 ? 23.482 78.730 -9.545 1.00 12.42 ? 788 THR A C 1 ATOM 6206 O O . THR A 1 788 ? 24.569 78.771 -8.943 1.00 14.61 ? 788 THR A O 1 ATOM 6207 C CB . THR A 1 788 ? 22.899 81.053 -10.271 1.00 13.67 ? 788 THR A CB 1 ATOM 6208 O OG1 . THR A 1 788 ? 21.895 82.095 -10.128 1.00 16.54 ? 788 THR A OG1 1 ATOM 6209 C CG2 . THR A 1 788 ? 23.018 80.619 -11.754 1.00 17.86 ? 788 THR A CG2 1 ATOM 6210 N N . GLU A 1 789 ? 23.107 77.759 -10.363 1.00 11.13 ? 789 GLU A N 1 ATOM 6211 C CA . GLU A 1 789 ? 24.088 76.709 -10.741 1.00 10.92 ? 789 GLU A CA 1 ATOM 6212 C C . GLU A 1 789 ? 24.092 76.711 -12.278 1.00 11.85 ? 789 GLU A C 1 ATOM 6213 O O . GLU A 1 789 ? 23.037 76.585 -12.914 1.00 13.93 ? 789 GLU A O 1 ATOM 6214 C CB . GLU A 1 789 ? 23.676 75.314 -10.172 1.00 12.97 ? 789 GLU A CB 1 ATOM 6215 C CG . GLU A 1 789 ? 23.347 75.398 -8.684 1.00 11.10 ? 789 GLU A CG 1 ATOM 6216 C CD . GLU A 1 789 ? 23.565 74.090 -7.924 1.00 13.05 ? 789 GLU A CD 1 ATOM 6217 O OE1 . GLU A 1 789 ? 24.381 73.279 -8.419 1.00 9.71 ? 789 GLU A OE1 1 ATOM 6218 O OE2 . GLU A 1 789 ? 22.946 73.898 -6.849 1.00 12.07 ? 789 GLU A OE2 1 ATOM 6219 N N . ILE A 1 790 ? 25.249 76.913 -12.886 1.00 9.83 ? 790 ILE A N 1 ATOM 6220 C CA . ILE A 1 790 ? 25.364 76.971 -14.322 1.00 11.38 ? 790 ILE A CA 1 ATOM 6221 C C . ILE A 1 790 ? 25.720 75.599 -14.848 1.00 10.65 ? 790 ILE A C 1 ATOM 6222 O O . ILE A 1 790 ? 26.702 75.009 -14.375 1.00 11.13 ? 790 ILE A O 1 ATOM 6223 C CB . ILE A 1 790 ? 26.477 77.940 -14.682 1.00 11.81 ? 790 ILE A CB 1 ATOM 6224 C CG1 . ILE A 1 790 ? 26.138 79.307 -14.041 1.00 14.33 ? 790 ILE A CG1 1 ATOM 6225 C CG2 . ILE A 1 790 ? 26.694 78.006 -16.218 1.00 11.99 ? 790 ILE A CG2 1 ATOM 6226 C CD1 . ILE A 1 790 ? 27.179 80.396 -14.283 1.00 18.20 ? 790 ILE A CD1 1 ATOM 6227 N N . VAL A 1 791 ? 24.948 75.085 -15.788 1.00 10.72 ? 791 VAL A N 1 ATOM 6228 C CA . VAL A 1 791 ? 25.169 73.804 -16.402 1.00 10.72 ? 791 VAL A CA 1 ATOM 6229 C C . VAL A 1 791 ? 25.394 73.927 -17.887 1.00 11.96 ? 791 VAL A C 1 ATOM 6230 O O . VAL A 1 791 ? 24.814 74.811 -18.583 1.00 11.65 ? 791 VAL A O 1 ATOM 6231 C CB . VAL A 1 791 ? 23.929 72.850 -16.129 1.00 11.42 ? 791 VAL A CB 1 ATOM 6232 C CG1 . VAL A 1 791 ? 22.610 73.422 -16.810 1.00 12.19 ? 791 VAL A CG1 1 ATOM 6233 C CG2 . VAL A 1 791 ? 24.251 71.393 -16.641 1.00 11.16 ? 791 VAL A CG2 1 ATOM 6234 N N . MET A 1 792 ? 26.273 73.095 -18.403 1.00 9.65 ? 792 MET A N 1 ATOM 6235 C CA . MET A 1 792 ? 26.531 72.982 -19.835 1.00 10.38 ? 792 MET A CA 1 ATOM 6236 C C . MET A 1 792 ? 25.911 71.646 -20.255 1.00 11.60 ? 792 MET A C 1 ATOM 6237 O O . MET A 1 792 ? 26.216 70.589 -19.685 1.00 10.98 ? 792 MET A O 1 ATOM 6238 C CB . MET A 1 792 ? 28.035 72.986 -20.142 1.00 8.85 ? 792 MET A CB 1 ATOM 6239 C CG . MET A 1 792 ? 28.385 72.700 -21.571 1.00 10.96 ? 792 MET A CG 1 ATOM 6240 S SD . MET A 1 792 ? 30.150 72.821 -21.999 1.00 12.04 ? 792 MET A SD 1 ATOM 6241 C CE . MET A 1 792 ? 30.731 71.206 -21.172 1.00 9.79 ? 792 MET A CE 1 ATOM 6242 N N . ARG A 1 793 ? 24.993 71.708 -21.227 1.00 10.81 ? 793 ARG A N 1 ATOM 6243 C CA . ARG A 1 793 ? 24.245 70.584 -21.801 1.00 11.03 ? 793 ARG A CA 1 ATOM 6244 C C . ARG A 1 793 ? 24.582 70.335 -23.285 1.00 12.26 ? 793 ARG A C 1 ATOM 6245 O O . ARG A 1 793 ? 24.794 71.264 -24.082 1.00 14.80 ? 793 ARG A O 1 ATOM 6246 C CB . ARG A 1 793 ? 22.703 70.786 -21.633 1.00 12.16 ? 793 ARG A CB 1 ATOM 6247 C CG . ARG A 1 793 ? 21.884 69.550 -22.059 1.00 12.35 ? 793 ARG A CG 1 ATOM 6248 C CD . ARG A 1 793 ? 20.371 69.838 -21.781 1.00 11.55 ? 793 ARG A CD 1 ATOM 6249 N NE . ARG A 1 793 ? 20.149 69.898 -20.342 1.00 12.76 ? 793 ARG A NE 1 ATOM 6250 C CZ . ARG A 1 793 ? 19.098 70.455 -19.786 1.00 14.05 ? 793 ARG A CZ 1 ATOM 6251 N NH1 . ARG A 1 793 ? 18.160 71.009 -20.585 1.00 12.56 ? 793 ARG A NH1 1 ATOM 6252 N NH2 . ARG A 1 793 ? 18.988 70.506 -18.473 1.00 11.60 ? 793 ARG A NH2 1 ATOM 6253 N N . LEU A 1 794 ? 24.552 69.081 -23.666 1.00 12.90 ? 794 LEU A N 1 ATOM 6254 C CA . LEU A 1 794 ? 24.725 68.681 -25.027 1.00 12.84 ? 794 LEU A CA 1 ATOM 6255 C C . LEU A 1 794 ? 23.419 68.017 -25.428 1.00 13.16 ? 794 LEU A C 1 ATOM 6256 O O . LEU A 1 794 ? 22.951 67.080 -24.775 1.00 12.27 ? 794 LEU A O 1 ATOM 6257 C CB . LEU A 1 794 ? 25.850 67.673 -25.185 1.00 14.65 ? 794 LEU A CB 1 ATOM 6258 C CG . LEU A 1 794 ? 27.196 68.374 -25.217 1.00 13.75 ? 794 LEU A CG 1 ATOM 6259 C CD1 . LEU A 1 794 ? 28.266 67.437 -24.834 1.00 15.94 ? 794 LEU A CD1 1 ATOM 6260 C CD2 . LEU A 1 794 ? 27.450 68.914 -26.606 1.00 16.20 ? 794 LEU A CD2 1 ATOM 6261 N N . GLU A 1 795 ? 22.816 68.510 -26.512 1.00 14.65 ? 795 GLU A N 1 ATOM 6262 C CA . GLU A 1 795 ? 21.588 67.924 -27.032 1.00 15.02 ? 795 GLU A CA 1 ATOM 6263 C C . GLU A 1 795 ? 21.866 67.184 -28.331 1.00 15.37 ? 795 GLU A C 1 ATOM 6264 O O . GLU A 1 795 ? 22.487 67.732 -29.268 1.00 16.62 ? 795 GLU A O 1 ATOM 6265 C CB . GLU A 1 795 ? 20.515 69.000 -27.238 1.00 15.58 ? 795 GLU A CB 1 ATOM 6266 C CG . GLU A 1 795 ? 20.169 69.734 -25.926 1.00 17.17 ? 795 GLU A CG 1 ATOM 6267 C CD . GLU A 1 795 ? 19.254 70.962 -26.136 1.00 20.23 ? 795 GLU A CD 1 ATOM 6268 O OE1 . GLU A 1 795 ? 19.360 71.638 -27.168 1.00 22.95 ? 795 GLU A OE1 1 ATOM 6269 O OE2 . GLU A 1 795 ? 18.437 71.288 -25.272 1.00 23.24 ? 795 GLU A OE2 1 ATOM 6270 N N . THR A 1 796 ? 21.486 65.910 -28.384 1.00 14.03 ? 796 THR A N 1 ATOM 6271 C CA . THR A 1 796 ? 21.698 65.127 -29.592 1.00 14.05 ? 796 THR A CA 1 ATOM 6272 C C . THR A 1 796 ? 20.421 64.322 -29.823 1.00 13.95 ? 796 THR A C 1 ATOM 6273 O O . THR A 1 796 ? 19.434 64.368 -29.023 1.00 16.80 ? 796 THR A O 1 ATOM 6274 C CB . THR A 1 796 ? 22.888 64.150 -29.483 1.00 12.92 ? 796 THR A CB 1 ATOM 6275 O OG1 . THR A 1 796 ? 22.494 62.983 -28.757 1.00 14.09 ? 796 THR A OG1 1 ATOM 6276 C CG2 . THR A 1 796 ? 24.040 64.833 -28.694 1.00 14.26 ? 796 THR A CG2 1 ATOM 6277 N N . HIS A 1 797 ? 20.424 63.598 -30.915 1.00 16.25 ? 797 HIS A N 1 ATOM 6278 C CA . HIS A 1 797 ? 19.274 62.771 -31.246 1.00 18.06 ? 797 HIS A CA 1 ATOM 6279 C C . HIS A 1 797 ? 19.672 61.304 -31.052 1.00 18.07 ? 797 HIS A C 1 ATOM 6280 O O . HIS A 1 797 ? 19.024 60.391 -31.600 1.00 20.06 ? 797 HIS A O 1 ATOM 6281 C CB . HIS A 1 797 ? 18.814 63.119 -32.683 1.00 18.32 ? 797 HIS A CB 1 ATOM 6282 C CG . HIS A 1 797 ? 18.270 64.503 -32.798 1.00 16.77 ? 797 HIS A CG 1 ATOM 6283 N ND1 . HIS A 1 797 ? 17.964 65.089 -34.005 1.00 16.71 ? 797 HIS A ND1 1 ATOM 6284 C CD2 . HIS A 1 797 ? 17.926 65.406 -31.851 1.00 17.58 ? 797 HIS A CD2 1 ATOM 6285 C CE1 . HIS A 1 797 ? 17.439 66.279 -33.795 1.00 19.29 ? 797 HIS A CE1 1 ATOM 6286 N NE2 . HIS A 1 797 ? 17.403 66.500 -32.498 1.00 20.25 ? 797 HIS A NE2 1 ATOM 6287 N N . ILE A 1 798 ? 20.735 61.054 -30.265 1.00 15.53 ? 798 ILE A N 1 ATOM 6288 C CA . ILE A 1 798 ? 21.184 59.664 -29.987 1.00 12.95 ? 798 ILE A CA 1 ATOM 6289 C C . ILE A 1 798 ? 20.062 59.051 -29.135 1.00 12.91 ? 798 ILE A C 1 ATOM 6290 O O . ILE A 1 798 ? 19.576 59.651 -28.194 1.00 14.08 ? 798 ILE A O 1 ATOM 6291 C CB . ILE A 1 798 ? 22.550 59.681 -29.231 1.00 13.89 ? 798 ILE A CB 1 ATOM 6292 C CG1 . ILE A 1 798 ? 23.595 60.269 -30.145 1.00 13.46 ? 798 ILE A CG1 1 ATOM 6293 C CG2 . ILE A 1 798 ? 22.981 58.292 -28.783 1.00 15.45 ? 798 ILE A CG2 1 ATOM 6294 C CD1 . ILE A 1 798 ? 24.839 60.814 -29.324 1.00 15.12 ? 798 ILE A CD1 1 ATOM 6295 N N . ASP A 1 799 ? 19.647 57.848 -29.521 1.00 14.97 ? 799 ASP A N 1 ATOM 6296 C CA . ASP A 1 799 ? 18.533 57.155 -28.856 1.00 14.19 ? 799 ASP A CA 1 ATOM 6297 C C . ASP A 1 799 ? 19.091 56.359 -27.645 1.00 15.32 ? 799 ASP A C 1 ATOM 6298 O O . ASP A 1 799 ? 19.099 55.139 -27.653 1.00 13.98 ? 799 ASP A O 1 ATOM 6299 C CB . ASP A 1 799 ? 17.884 56.247 -29.907 1.00 18.02 ? 799 ASP A CB 1 ATOM 6300 C CG . ASP A 1 799 ? 16.639 55.593 -29.427 1.00 19.56 ? 799 ASP A CG 1 ATOM 6301 O OD1 . ASP A 1 799 ? 16.015 56.062 -28.469 1.00 23.47 ? 799 ASP A OD1 1 ATOM 6302 O OD2 . ASP A 1 799 ? 16.285 54.581 -30.038 1.00 24.21 ? 799 ASP A OD2 1 ATOM 6303 N N . SER A 1 800 ? 19.557 57.097 -26.645 1.00 14.82 ? 800 SER A N 1 ATOM 6304 C CA . SER A 1 800 ? 20.147 56.509 -25.460 1.00 14.25 ? 800 SER A CA 1 ATOM 6305 C C . SER A 1 800 ? 19.083 56.088 -24.465 1.00 13.96 ? 800 SER A C 1 ATOM 6306 O O . SER A 1 800 ? 19.375 55.274 -23.587 1.00 14.38 ? 800 SER A O 1 ATOM 6307 C CB . SER A 1 800 ? 21.085 57.510 -24.769 1.00 12.32 ? 800 SER A CB 1 ATOM 6308 O OG . SER A 1 800 ? 20.423 58.724 -24.488 1.00 12.54 ? 800 SER A OG 1 ATOM 6309 N N . GLY A 1 801 ? 17.878 56.648 -24.559 1.00 12.94 ? 801 GLY A N 1 ATOM 6310 C CA . GLY A 1 801 ? 16.793 56.269 -23.668 1.00 12.28 ? 801 GLY A CA 1 ATOM 6311 C C . GLY A 1 801 ? 17.028 56.753 -22.266 1.00 13.12 ? 801 GLY A C 1 ATOM 6312 O O . GLY A 1 801 ? 17.061 57.965 -22.055 1.00 13.95 ? 801 GLY A O 1 ATOM 6313 N N . ASP A 1 802 ? 17.186 55.818 -21.318 1.00 12.46 ? 802 ASP A N 1 ATOM 6314 C CA . ASP A 1 802 ? 17.421 56.207 -19.918 1.00 13.45 ? 802 ASP A CA 1 ATOM 6315 C C . ASP A 1 802 ? 18.841 55.773 -19.446 1.00 13.07 ? 802 ASP A C 1 ATOM 6316 O O . ASP A 1 802 ? 19.178 55.837 -18.254 1.00 11.54 ? 802 ASP A O 1 ATOM 6317 C CB . ASP A 1 802 ? 16.285 55.620 -19.023 1.00 13.58 ? 802 ASP A CB 1 ATOM 6318 C CG . ASP A 1 802 ? 16.187 54.108 -19.085 1.00 16.68 ? 802 ASP A CG 1 ATOM 6319 O OD1 . ASP A 1 802 ? 17.038 53.487 -19.732 1.00 18.02 ? 802 ASP A OD1 1 ATOM 6320 O OD2 . ASP A 1 802 ? 15.218 53.543 -18.458 1.00 18.55 ? 802 ASP A OD2 1 ATOM 6321 N N . ILE A 1 803 ? 19.666 55.359 -20.404 1.00 11.13 ? 803 ILE A N 1 ATOM 6322 C CA . ILE A 1 803 ? 21.024 54.891 -20.074 1.00 11.34 ? 803 ILE A CA 1 ATOM 6323 C C . ILE A 1 803 ? 22.120 55.908 -20.412 1.00 10.19 ? 803 ILE A C 1 ATOM 6324 O O . ILE A 1 803 ? 22.122 56.555 -21.466 1.00 10.77 ? 803 ILE A O 1 ATOM 6325 C CB . ILE A 1 803 ? 21.372 53.595 -20.875 1.00 10.84 ? 803 ILE A CB 1 ATOM 6326 C CG1 . ILE A 1 803 ? 20.322 52.529 -20.582 1.00 13.18 ? 803 ILE A CG1 1 ATOM 6327 C CG2 . ILE A 1 803 ? 22.815 53.143 -20.634 1.00 12.43 ? 803 ILE A CG2 1 ATOM 6328 C CD1 . ILE A 1 803 ? 20.195 52.173 -19.091 1.00 12.63 ? 803 ILE A CD1 1 ATOM 6329 N N . PHE A 1 804 ? 23.124 55.973 -19.534 1.00 9.93 ? 804 PHE A N 1 ATOM 6330 C CA . PHE A 1 804 ? 24.320 56.801 -19.783 1.00 9.00 ? 804 PHE A CA 1 ATOM 6331 C C . PHE A 1 804 ? 25.459 56.193 -18.956 1.00 8.63 ? 804 PHE A C 1 ATOM 6332 O O . PHE A 1 804 ? 25.256 55.248 -18.162 1.00 9.60 ? 804 PHE A O 1 ATOM 6333 C CB . PHE A 1 804 ? 24.112 58.296 -19.457 1.00 8.65 ? 804 PHE A CB 1 ATOM 6334 C CG . PHE A 1 804 ? 23.716 58.605 -18.028 1.00 6.65 ? 804 PHE A CG 1 ATOM 6335 C CD1 . PHE A 1 804 ? 22.405 58.356 -17.561 1.00 8.35 ? 804 PHE A CD1 1 ATOM 6336 C CD2 . PHE A 1 804 ? 24.637 59.225 -17.131 1.00 10.32 ? 804 PHE A CD2 1 ATOM 6337 C CE1 . PHE A 1 804 ? 22.051 58.734 -16.275 1.00 9.41 ? 804 PHE A CE1 1 ATOM 6338 C CE2 . PHE A 1 804 ? 24.267 59.586 -15.863 1.00 7.94 ? 804 PHE A CE2 1 ATOM 6339 C CZ . PHE A 1 804 ? 22.970 59.363 -15.411 1.00 10.46 ? 804 PHE A CZ 1 ATOM 6340 N N . TYR A 1 805 ? 26.655 56.683 -19.176 1.00 8.27 ? 805 TYR A N 1 ATOM 6341 C CA . TYR A 1 805 ? 27.790 56.132 -18.482 1.00 7.80 ? 805 TYR A CA 1 ATOM 6342 C C . TYR A 1 805 ? 28.631 57.243 -17.899 1.00 9.71 ? 805 TYR A C 1 ATOM 6343 O O . TYR A 1 805 ? 28.802 58.304 -18.495 1.00 9.90 ? 805 TYR A O 1 ATOM 6344 C CB . TYR A 1 805 ? 28.658 55.313 -19.466 1.00 9.75 ? 805 TYR A CB 1 ATOM 6345 C CG . TYR A 1 805 ? 27.984 54.088 -20.065 1.00 7.77 ? 805 TYR A CG 1 ATOM 6346 C CD1 . TYR A 1 805 ? 27.024 54.218 -21.093 1.00 9.38 ? 805 TYR A CD1 1 ATOM 6347 C CD2 . TYR A 1 805 ? 28.272 52.809 -19.577 1.00 10.34 ? 805 TYR A CD2 1 ATOM 6348 C CE1 . TYR A 1 805 ? 26.373 53.076 -21.584 1.00 11.65 ? 805 TYR A CE1 1 ATOM 6349 C CE2 . TYR A 1 805 ? 27.633 51.662 -20.073 1.00 8.84 ? 805 TYR A CE2 1 ATOM 6350 C CZ . TYR A 1 805 ? 26.685 51.824 -21.076 1.00 10.83 ? 805 TYR A CZ 1 ATOM 6351 O OH . TYR A 1 805 ? 26.081 50.674 -21.535 1.00 12.02 ? 805 TYR A OH 1 ATOM 6352 N N . THR A 1 806 ? 29.103 57.004 -16.678 1.00 9.70 ? 806 THR A N 1 ATOM 6353 C CA . THR A 1 806 ? 30.012 57.940 -16.026 1.00 8.18 ? 806 THR A CA 1 ATOM 6354 C C . THR A 1 806 ? 31.200 57.150 -15.472 1.00 9.27 ? 806 THR A C 1 ATOM 6355 O O . THR A 1 806 ? 31.099 55.951 -15.276 1.00 10.03 ? 806 THR A O 1 ATOM 6356 C CB . THR A 1 806 ? 29.317 58.721 -14.896 1.00 8.27 ? 806 THR A CB 1 ATOM 6357 O OG1 . THR A 1 806 ? 28.875 57.850 -13.849 1.00 7.63 ? 806 THR A OG1 1 ATOM 6358 C CG2 . THR A 1 806 ? 28.032 59.403 -15.419 1.00 8.49 ? 806 THR A CG2 1 ATOM 6359 N N . ASP A 1 807 ? 32.307 57.829 -15.193 1.00 9.18 ? 807 ASP A N 1 ATOM 6360 C CA . ASP A 1 807 ? 33.435 57.094 -14.598 1.00 7.28 ? 807 ASP A CA 1 ATOM 6361 C C . ASP A 1 807 ? 33.516 57.189 -13.095 1.00 6.16 ? 807 ASP A C 1 ATOM 6362 O O . ASP A 1 807 ? 32.900 58.026 -12.413 1.00 8.71 ? 807 ASP A O 1 ATOM 6363 C CB . ASP A 1 807 ? 34.776 57.524 -15.207 1.00 8.93 ? 807 ASP A CB 1 ATOM 6364 C CG . ASP A 1 807 ? 35.224 58.880 -14.754 1.00 8.94 ? 807 ASP A CG 1 ATOM 6365 O OD1 . ASP A 1 807 ? 34.455 59.880 -14.840 1.00 9.40 ? 807 ASP A OD1 1 ATOM 6366 O OD2 . ASP A 1 807 ? 36.391 58.951 -14.248 1.00 9.10 ? 807 ASP A OD2 1 ATOM 6367 N N . LEU A 1 808 ? 34.265 56.232 -12.567 1.00 7.28 ? 808 LEU A N 1 ATOM 6368 C CA . LEU A 1 808 ? 34.576 56.214 -11.137 1.00 6.64 ? 808 LEU A CA 1 ATOM 6369 C C . LEU A 1 808 ? 36.072 56.444 -10.941 1.00 7.22 ? 808 LEU A C 1 ATOM 6370 O O . LEU A 1 808 ? 36.895 55.634 -11.399 1.00 6.21 ? 808 LEU A O 1 ATOM 6371 C CB . LEU A 1 808 ? 34.195 54.867 -10.486 1.00 6.74 ? 808 LEU A CB 1 ATOM 6372 C CG . LEU A 1 808 ? 32.662 54.688 -10.446 1.00 6.11 ? 808 LEU A CG 1 ATOM 6373 C CD1 . LEU A 1 808 ? 32.277 53.231 -10.284 1.00 6.30 ? 808 LEU A CD1 1 ATOM 6374 C CD2 . LEU A 1 808 ? 32.024 55.529 -9.306 1.00 7.94 ? 808 LEU A CD2 1 ATOM 6375 N N . ASN A 1 809 ? 36.417 57.580 -10.337 1.00 7.33 ? 809 ASN A N 1 ATOM 6376 C CA . ASN A 1 809 ? 37.826 57.909 -10.029 1.00 7.66 ? 809 ASN A CA 1 ATOM 6377 C C . ASN A 1 809 ? 38.795 57.813 -11.231 1.00 6.86 ? 809 ASN A C 1 ATOM 6378 O O . ASN A 1 809 ? 39.977 57.552 -11.060 1.00 7.01 ? 809 ASN A O 1 ATOM 6379 C CB . ASN A 1 809 ? 38.312 57.023 -8.829 1.00 6.60 ? 809 ASN A CB 1 ATOM 6380 C CG . ASN A 1 809 ? 37.264 56.907 -7.796 1.00 6.33 ? 809 ASN A CG 1 ATOM 6381 O OD1 . ASN A 1 809 ? 36.393 55.990 -7.885 1.00 6.55 ? 809 ASN A OD1 1 ATOM 6382 N ND2 . ASN A 1 809 ? 37.258 57.863 -6.851 1.00 7.21 ? 809 ASN A ND2 1 ATOM 6383 N N . GLY A 1 810 ? 38.336 58.042 -12.450 1.00 8.67 ? 810 GLY A N 1 ATOM 6384 C CA . GLY A 1 810 ? 39.263 57.986 -13.573 1.00 8.15 ? 810 GLY A CA 1 ATOM 6385 C C . GLY A 1 810 ? 39.727 56.567 -13.842 1.00 8.58 ? 810 GLY A C 1 ATOM 6386 O O . GLY A 1 810 ? 40.676 56.366 -14.610 1.00 8.30 ? 810 GLY A O 1 ATOM 6387 N N . LEU A 1 811 ? 39.047 55.582 -13.270 1.00 7.76 ? 811 LEU A N 1 ATOM 6388 C CA . LEU A 1 811 ? 39.510 54.189 -13.402 1.00 7.13 ? 811 LEU A CA 1 ATOM 6389 C C . LEU A 1 811 ? 38.681 53.263 -14.257 1.00 9.31 ? 811 LEU A C 1 ATOM 6390 O O . LEU A 1 811 ? 39.226 52.398 -14.946 1.00 10.27 ? 811 LEU A O 1 ATOM 6391 C CB . LEU A 1 811 ? 39.579 53.579 -11.992 1.00 10.03 ? 811 LEU A CB 1 ATOM 6392 C CG . LEU A 1 811 ? 40.027 52.137 -11.863 1.00 10.05 ? 811 LEU A CG 1 ATOM 6393 C CD1 . LEU A 1 811 ? 41.457 52.046 -12.265 1.00 11.42 ? 811 LEU A CD1 1 ATOM 6394 C CD2 . LEU A 1 811 ? 39.883 51.637 -10.426 1.00 10.85 ? 811 LEU A CD2 1 ATOM 6395 N N . GLN A 1 812 ? 37.371 53.462 -14.217 1.00 8.17 ? 812 GLN A N 1 ATOM 6396 C CA . GLN A 1 812 ? 36.408 52.584 -14.863 1.00 8.36 ? 812 GLN A CA 1 ATOM 6397 C C . GLN A 1 812 ? 35.158 53.332 -15.183 1.00 7.55 ? 812 GLN A C 1 ATOM 6398 O O . GLN A 1 812 ? 34.845 54.314 -14.532 1.00 8.36 ? 812 GLN A O 1 ATOM 6399 C CB . GLN A 1 812 ? 36.082 51.452 -13.916 1.00 9.62 ? 812 GLN A CB 1 ATOM 6400 C CG . GLN A 1 812 ? 35.416 51.918 -12.583 1.00 10.00 ? 812 GLN A CG 1 ATOM 6401 C CD . GLN A 1 812 ? 35.190 50.785 -11.619 1.00 13.37 ? 812 GLN A CD 1 ATOM 6402 O OE1 . GLN A 1 812 ? 34.272 49.980 -11.783 1.00 13.00 ? 812 GLN A OE1 1 ATOM 6403 N NE2 . GLN A 1 812 ? 36.044 50.710 -10.605 1.00 14.81 ? 812 GLN A NE2 1 ATOM 6404 N N . PHE A 1 813 ? 34.401 52.847 -16.173 1.00 9.03 ? 813 PHE A N 1 ATOM 6405 C CA . PHE A 1 813 ? 33.141 53.486 -16.525 1.00 8.14 ? 813 PHE A CA 1 ATOM 6406 C C . PHE A 1 813 ? 32.017 52.571 -16.095 1.00 8.12 ? 813 PHE A C 1 ATOM 6407 O O . PHE A 1 813 ? 32.039 51.406 -16.388 1.00 9.42 ? 813 PHE A O 1 ATOM 6408 C CB . PHE A 1 813 ? 33.098 53.754 -18.044 1.00 8.71 ? 813 PHE A CB 1 ATOM 6409 C CG . PHE A 1 813 ? 33.856 54.993 -18.417 1.00 6.52 ? 813 PHE A CG 1 ATOM 6410 C CD1 . PHE A 1 813 ? 35.239 54.967 -18.462 1.00 8.25 ? 813 PHE A CD1 1 ATOM 6411 C CD2 . PHE A 1 813 ? 33.188 56.190 -18.627 1.00 8.67 ? 813 PHE A CD2 1 ATOM 6412 C CE1 . PHE A 1 813 ? 35.975 56.147 -18.709 1.00 10.11 ? 813 PHE A CE1 1 ATOM 6413 C CE2 . PHE A 1 813 ? 33.891 57.369 -18.882 1.00 10.24 ? 813 PHE A CE2 1 ATOM 6414 C CZ . PHE A 1 813 ? 35.308 57.336 -18.925 1.00 10.18 ? 813 PHE A CZ 1 ATOM 6415 N N . ILE A 1 814 ? 31.022 53.117 -15.444 1.00 7.58 ? 814 ILE A N 1 ATOM 6416 C CA . ILE A 1 814 ? 29.891 52.343 -14.945 1.00 6.39 ? 814 ILE A CA 1 ATOM 6417 C C . ILE A 1 814 ? 28.606 52.798 -15.580 1.00 7.72 ? 814 ILE A C 1 ATOM 6418 O O . ILE A 1 814 ? 28.399 53.977 -15.824 1.00 7.21 ? 814 ILE A O 1 ATOM 6419 C CB . ILE A 1 814 ? 29.855 52.470 -13.369 1.00 6.93 ? 814 ILE A CB 1 ATOM 6420 C CG1 . ILE A 1 814 ? 28.781 51.505 -12.772 1.00 7.54 ? 814 ILE A CG1 1 ATOM 6421 C CG2 . ILE A 1 814 ? 29.625 53.954 -12.880 1.00 7.78 ? 814 ILE A CG2 1 ATOM 6422 C CD1 . ILE A 1 814 ? 28.951 51.323 -11.188 1.00 7.90 ? 814 ILE A CD1 1 ATOM 6423 N N . LYS A 1 815 ? 27.763 51.825 -15.955 1.00 7.59 ? 815 LYS A N 1 ATOM 6424 C CA . LYS A 1 815 ? 26.439 52.088 -16.536 1.00 8.53 ? 815 LYS A CA 1 ATOM 6425 C C . LYS A 1 815 ? 25.504 52.697 -15.502 1.00 7.88 ? 815 LYS A C 1 ATOM 6426 O O . LYS A 1 815 ? 25.399 52.197 -14.340 1.00 7.67 ? 815 LYS A O 1 ATOM 6427 C CB . LYS A 1 815 ? 25.825 50.783 -16.955 1.00 10.52 ? 815 LYS A CB 1 ATOM 6428 C CG . LYS A 1 815 ? 24.513 50.935 -17.851 1.00 7.96 ? 815 LYS A CG 1 ATOM 6429 C CD . LYS A 1 815 ? 24.176 49.506 -18.348 1.00 11.18 ? 815 LYS A CD 1 ATOM 6430 C CE . LYS A 1 815 ? 23.128 49.465 -19.446 1.00 14.78 ? 815 LYS A CE 1 ATOM 6431 N NZ . LYS A 1 815 ? 23.123 47.991 -19.892 1.00 18.17 ? 815 LYS A NZ 1 ATOM 6432 N N . ARG A 1 816 ? 24.853 53.790 -15.914 1.00 8.99 ? 816 ARG A N 1 ATOM 6433 C CA . ARG A 1 816 ? 23.876 54.478 -15.067 1.00 7.61 ? 816 ARG A CA 1 ATOM 6434 C C . ARG A 1 816 ? 22.515 54.350 -15.782 1.00 5.73 ? 816 ARG A C 1 ATOM 6435 O O . ARG A 1 816 ? 22.434 54.287 -16.999 1.00 9.63 ? 816 ARG A O 1 ATOM 6436 C CB . ARG A 1 816 ? 24.162 56.022 -14.859 1.00 7.74 ? 816 ARG A CB 1 ATOM 6437 C CG . ARG A 1 816 ? 25.527 56.329 -14.314 1.00 8.92 ? 816 ARG A CG 1 ATOM 6438 C CD . ARG A 1 816 ? 25.710 55.639 -12.981 1.00 7.44 ? 816 ARG A CD 1 ATOM 6439 N NE . ARG A 1 816 ? 26.914 56.219 -12.363 1.00 8.03 ? 816 ARG A NE 1 ATOM 6440 C CZ . ARG A 1 816 ? 27.339 55.841 -11.163 1.00 7.46 ? 816 ARG A CZ 1 ATOM 6441 N NH1 . ARG A 1 816 ? 26.685 54.882 -10.501 1.00 8.37 ? 816 ARG A NH1 1 ATOM 6442 N NH2 . ARG A 1 816 ? 28.379 56.435 -10.584 1.00 7.18 ? 816 ARG A NH2 1 ATOM 6443 N N . ARG A 1 817 ? 21.445 54.309 -14.989 1.00 9.33 ? 817 ARG A N 1 ATOM 6444 C CA . ARG A 1 817 ? 20.102 54.320 -15.563 1.00 8.19 ? 817 ARG A CA 1 ATOM 6445 C C . ARG A 1 817 ? 19.367 55.448 -14.812 1.00 9.07 ? 817 ARG A C 1 ATOM 6446 O O . ARG A 1 817 ? 19.254 55.462 -13.557 1.00 9.18 ? 817 ARG A O 1 ATOM 6447 C CB . ARG A 1 817 ? 19.366 52.947 -15.379 1.00 9.75 ? 817 ARG A CB 1 ATOM 6448 C CG . ARG A 1 817 ? 17.872 53.065 -15.708 1.00 10.42 ? 817 ARG A CG 1 ATOM 6449 C CD . ARG A 1 817 ? 17.139 51.688 -15.546 1.00 14.14 ? 817 ARG A CD 1 ATOM 6450 N NE . ARG A 1 817 ? 17.722 50.685 -16.435 1.00 13.92 ? 817 ARG A NE 1 ATOM 6451 C CZ . ARG A 1 817 ? 18.500 49.680 -16.067 1.00 15.43 ? 817 ARG A CZ 1 ATOM 6452 N NH1 . ARG A 1 817 ? 18.817 49.496 -14.786 1.00 13.92 ? 817 ARG A NH1 1 ATOM 6453 N NH2 . ARG A 1 817 ? 18.936 48.825 -16.979 1.00 18.31 ? 817 ARG A NH2 1 ATOM 6454 N N . ARG A 1 818 ? 18.911 56.400 -15.645 1.00 9.37 ? 818 ARG A N 1 ATOM 6455 C CA . ARG A 1 818 ? 18.103 57.498 -15.176 1.00 11.68 ? 818 ARG A CA 1 ATOM 6456 C C . ARG A 1 818 ? 16.784 56.908 -14.642 1.00 11.54 ? 818 ARG A C 1 ATOM 6457 O O . ARG A 1 818 ? 16.148 56.135 -15.329 1.00 13.07 ? 818 ARG A O 1 ATOM 6458 C CB . ARG A 1 818 ? 17.753 58.416 -16.362 1.00 11.75 ? 818 ARG A CB 1 ATOM 6459 C CG . ARG A 1 818 ? 17.120 59.684 -15.859 1.00 12.54 ? 818 ARG A CG 1 ATOM 6460 C CD . ARG A 1 818 ? 16.423 60.500 -16.967 1.00 15.58 ? 818 ARG A CD 1 ATOM 6461 N NE . ARG A 1 818 ? 15.131 59.897 -17.269 1.00 16.40 ? 818 ARG A NE 1 ATOM 6462 C CZ . ARG A 1 818 ? 14.806 59.289 -18.417 1.00 18.99 ? 818 ARG A CZ 1 ATOM 6463 N NH1 . ARG A 1 818 ? 15.668 59.172 -19.438 1.00 19.12 ? 818 ARG A NH1 1 ATOM 6464 N NH2 . ARG A 1 818 ? 13.575 58.794 -18.511 1.00 19.87 ? 818 ARG A NH2 1 ATOM 6465 N N . LEU A 1 819 ? 16.394 57.301 -13.429 1.00 10.69 ? 819 LEU A N 1 ATOM 6466 C CA . LEU A 1 819 ? 15.156 56.785 -12.808 1.00 11.32 ? 819 LEU A CA 1 ATOM 6467 C C . LEU A 1 819 ? 14.179 57.925 -12.508 1.00 13.93 ? 819 LEU A C 1 ATOM 6468 O O . LEU A 1 819 ? 14.440 58.802 -11.699 1.00 11.98 ? 819 LEU A O 1 ATOM 6469 C CB . LEU A 1 819 ? 15.488 56.016 -11.515 1.00 13.05 ? 819 LEU A CB 1 ATOM 6470 C CG . LEU A 1 819 ? 16.442 54.793 -11.645 1.00 13.27 ? 819 LEU A CG 1 ATOM 6471 C CD1 . LEU A 1 819 ? 16.842 54.339 -10.179 1.00 12.89 ? 819 LEU A CD1 1 ATOM 6472 C CD2 . LEU A 1 819 ? 15.860 53.658 -12.466 1.00 14.27 ? 819 LEU A CD2 1 ATOM 6473 N N . ASP A 1 820 ? 13.021 57.891 -13.179 1.00 14.82 ? 820 ASP A N 1 ATOM 6474 C CA . ASP A 1 820 ? 12.061 58.956 -12.920 1.00 15.05 ? 820 ASP A CA 1 ATOM 6475 C C . ASP A 1 820 ? 11.365 58.769 -11.558 1.00 13.06 ? 820 ASP A C 1 ATOM 6476 O O . ASP A 1 820 ? 10.705 59.672 -11.094 1.00 13.12 ? 820 ASP A O 1 ATOM 6477 C CB . ASP A 1 820 ? 11.077 59.107 -14.076 1.00 15.90 ? 820 ASP A CB 1 ATOM 6478 C CG . ASP A 1 820 ? 11.798 59.386 -15.426 1.00 17.21 ? 820 ASP A CG 1 ATOM 6479 O OD1 . ASP A 1 820 ? 12.925 59.964 -15.456 1.00 19.82 ? 820 ASP A OD1 1 ATOM 6480 O OD2 . ASP A 1 820 ? 11.237 59.019 -16.465 1.00 20.60 ? 820 ASP A OD2 1 ATOM 6481 N N . LYS A 1 821 ? 11.609 57.645 -10.865 1.00 12.80 ? 821 LYS A N 1 ATOM 6482 C CA . LYS A 1 821 ? 11.044 57.487 -9.520 1.00 12.78 ? 821 LYS A CA 1 ATOM 6483 C C . LYS A 1 821 ? 11.897 58.245 -8.506 1.00 14.42 ? 821 LYS A C 1 ATOM 6484 O O . LYS A 1 821 ? 11.492 58.438 -7.360 1.00 15.25 ? 821 LYS A O 1 ATOM 6485 C CB . LYS A 1 821 ? 10.958 56.007 -9.089 1.00 11.21 ? 821 LYS A CB 1 ATOM 6486 C CG . LYS A 1 821 ? 12.305 55.289 -9.015 1.00 10.74 ? 821 LYS A CG 1 ATOM 6487 C CD . LYS A 1 821 ? 12.059 53.791 -8.878 1.00 13.13 ? 821 LYS A CD 1 ATOM 6488 C CE . LYS A 1 821 ? 13.376 53.064 -8.905 1.00 13.52 ? 821 LYS A CE 1 ATOM 6489 N NZ . LYS A 1 821 ? 13.247 51.606 -8.948 1.00 13.43 ? 821 LYS A NZ 1 ATOM 6490 N N . LEU A 1 822 ? 13.075 58.705 -8.935 1.00 12.35 ? 822 LEU A N 1 ATOM 6491 C CA . LEU A 1 822 ? 13.919 59.490 -8.039 1.00 13.75 ? 822 LEU A CA 1 ATOM 6492 C C . LEU A 1 822 ? 13.923 60.934 -8.570 1.00 13.05 ? 822 LEU A C 1 ATOM 6493 O O . LEU A 1 822 ? 13.699 61.159 -9.763 1.00 11.72 ? 822 LEU A O 1 ATOM 6494 C CB . LEU A 1 822 ? 15.347 58.937 -7.978 1.00 14.82 ? 822 LEU A CB 1 ATOM 6495 C CG . LEU A 1 822 ? 15.496 57.502 -7.457 1.00 13.75 ? 822 LEU A CG 1 ATOM 6496 C CD1 . LEU A 1 822 ? 16.954 57.197 -7.432 1.00 16.60 ? 822 LEU A CD1 1 ATOM 6497 C CD2 . LEU A 1 822 ? 14.852 57.297 -6.117 1.00 15.03 ? 822 LEU A CD2 1 ATOM 6498 N N . PRO A 1 823 ? 14.147 61.915 -7.678 1.00 13.97 ? 823 PRO A N 1 ATOM 6499 C CA . PRO A 1 823 ? 14.179 63.323 -8.040 1.00 13.52 ? 823 PRO A CA 1 ATOM 6500 C C . PRO A 1 823 ? 15.390 63.636 -8.917 1.00 13.35 ? 823 PRO A C 1 ATOM 6501 O O . PRO A 1 823 ? 16.350 62.854 -9.010 1.00 14.70 ? 823 PRO A O 1 ATOM 6502 C CB . PRO A 1 823 ? 14.156 64.051 -6.687 1.00 14.97 ? 823 PRO A CB 1 ATOM 6503 C CG . PRO A 1 823 ? 14.764 63.087 -5.698 1.00 15.94 ? 823 PRO A CG 1 ATOM 6504 C CD . PRO A 1 823 ? 14.349 61.711 -6.222 1.00 13.76 ? 823 PRO A CD 1 ATOM 6505 N N . LEU A 1 824 ? 15.353 64.778 -9.618 1.00 12.67 ? 824 LEU A N 1 ATOM 6506 C CA . LEU A 1 824 ? 16.437 65.139 -10.539 1.00 10.71 ? 824 LEU A CA 1 ATOM 6507 C C . LEU A 1 824 ? 17.833 65.050 -9.875 1.00 11.22 ? 824 LEU A C 1 ATOM 6508 O O . LEU A 1 824 ? 18.763 64.501 -10.464 1.00 10.30 ? 824 LEU A O 1 ATOM 6509 C CB . LEU A 1 824 ? 16.155 66.581 -10.979 1.00 12.91 ? 824 LEU A CB 1 ATOM 6510 C CG . LEU A 1 824 ? 16.953 67.237 -12.120 1.00 11.75 ? 824 LEU A CG 1 ATOM 6511 C CD1 . LEU A 1 824 ? 16.199 68.497 -12.560 1.00 13.85 ? 824 LEU A CD1 1 ATOM 6512 C CD2 . LEU A 1 824 ? 18.377 67.644 -11.663 1.00 13.41 ? 824 LEU A CD2 1 ATOM 6513 N N . GLN A 1 825 ? 17.948 65.587 -8.671 1.00 9.94 ? 825 GLN A N 1 ATOM 6514 C CA . GLN A 1 825 ? 19.274 65.600 -8.041 1.00 10.35 ? 825 GLN A CA 1 ATOM 6515 C C . GLN A 1 825 ? 19.860 64.191 -7.783 1.00 10.66 ? 825 GLN A C 1 ATOM 6516 O O . GLN A 1 825 ? 21.107 64.035 -7.578 1.00 8.06 ? 825 GLN A O 1 ATOM 6517 C CB . GLN A 1 825 ? 19.267 66.454 -6.783 1.00 9.94 ? 825 GLN A CB 1 ATOM 6518 C CG . GLN A 1 825 ? 18.312 65.945 -5.688 1.00 8.88 ? 825 GLN A CG 1 ATOM 6519 C CD . GLN A 1 825 ? 16.844 66.423 -5.819 1.00 8.92 ? 825 GLN A CD 1 ATOM 6520 O OE1 . GLN A 1 825 ? 16.397 66.861 -6.872 1.00 13.03 ? 825 GLN A OE1 1 ATOM 6521 N NE2 . GLN A 1 825 ? 16.113 66.308 -4.757 1.00 11.99 ? 825 GLN A NE2 1 ATOM 6522 N N . ALA A 1 826 ? 18.970 63.190 -7.717 1.00 9.54 ? 826 ALA A N 1 ATOM 6523 C CA . ALA A 1 826 ? 19.409 61.808 -7.467 1.00 9.87 ? 826 ALA A CA 1 ATOM 6524 C C . ALA A 1 826 ? 19.994 61.219 -8.713 1.00 9.69 ? 826 ALA A C 1 ATOM 6525 O O . ALA A 1 826 ? 20.743 60.257 -8.609 1.00 10.27 ? 826 ALA A O 1 ATOM 6526 C CB . ALA A 1 826 ? 18.181 60.971 -6.983 1.00 10.69 ? 826 ALA A CB 1 ATOM 6527 N N . ASN A 1 827 ? 19.626 61.751 -9.901 1.00 8.81 ? 827 ASN A N 1 ATOM 6528 C CA . ASN A 1 827 ? 20.130 61.268 -11.182 1.00 8.19 ? 827 ASN A CA 1 ATOM 6529 C C . ASN A 1 827 ? 21.438 61.936 -11.594 1.00 7.20 ? 827 ASN A C 1 ATOM 6530 O O . ASN A 1 827 ? 21.927 61.604 -12.664 1.00 8.63 ? 827 ASN A O 1 ATOM 6531 C CB . ASN A 1 827 ? 19.032 61.383 -12.283 1.00 10.06 ? 827 ASN A CB 1 ATOM 6532 C CG . ASN A 1 827 ? 17.904 60.454 -12.002 1.00 13.12 ? 827 ASN A CG 1 ATOM 6533 O OD1 . ASN A 1 827 ? 18.073 59.240 -12.057 1.00 10.54 ? 827 ASN A OD1 1 ATOM 6534 N ND2 . ASN A 1 827 ? 16.742 61.011 -11.668 1.00 13.80 ? 827 ASN A ND2 1 ATOM 6535 N N . TYR A 1 828 ? 21.927 62.819 -10.716 1.00 9.49 ? 828 TYR A N 1 ATOM 6536 C CA . TYR A 1 828 ? 23.242 63.407 -10.895 1.00 8.17 ? 828 TYR A CA 1 ATOM 6537 C C . TYR A 1 828 ? 24.264 62.456 -10.306 1.00 10.27 ? 828 TYR A C 1 ATOM 6538 O O . TYR A 1 828 ? 24.037 61.930 -9.200 1.00 11.49 ? 828 TYR A O 1 ATOM 6539 C CB . TYR A 1 828 ? 23.352 64.730 -10.145 1.00 7.33 ? 828 TYR A CB 1 ATOM 6540 C CG . TYR A 1 828 ? 23.397 65.894 -11.139 1.00 10.74 ? 828 TYR A CG 1 ATOM 6541 C CD1 . TYR A 1 828 ? 22.343 66.108 -12.033 1.00 8.09 ? 828 TYR A CD1 1 ATOM 6542 C CD2 . TYR A 1 828 ? 24.484 66.755 -11.179 1.00 10.42 ? 828 TYR A CD2 1 ATOM 6543 C CE1 . TYR A 1 828 ? 22.366 67.158 -12.949 1.00 12.68 ? 828 TYR A CE1 1 ATOM 6544 C CE2 . TYR A 1 828 ? 24.541 67.783 -12.078 1.00 10.40 ? 828 TYR A CE2 1 ATOM 6545 C CZ . TYR A 1 828 ? 23.477 68.002 -12.978 1.00 9.93 ? 828 TYR A CZ 1 ATOM 6546 O OH . TYR A 1 828 ? 23.526 69.008 -13.923 1.00 11.83 ? 828 TYR A OH 1 ATOM 6547 N N . TYR A 1 829 ? 25.362 62.273 -11.040 1.00 8.14 ? 829 TYR A N 1 ATOM 6548 C CA . TYR A 1 829 ? 26.509 61.395 -10.638 1.00 7.47 ? 829 TYR A CA 1 ATOM 6549 C C . TYR A 1 829 ? 27.841 62.127 -10.771 1.00 8.96 ? 829 TYR A C 1 ATOM 6550 O O . TYR A 1 829 ? 27.936 63.226 -11.373 1.00 9.07 ? 829 TYR A O 1 ATOM 6551 C CB . TYR A 1 829 ? 26.543 60.120 -11.488 1.00 7.32 ? 829 TYR A CB 1 ATOM 6552 C CG . TYR A 1 829 ? 25.346 59.240 -11.213 1.00 8.70 ? 829 TYR A CG 1 ATOM 6553 C CD1 . TYR A 1 829 ? 25.412 58.345 -10.152 1.00 9.20 ? 829 TYR A CD1 1 ATOM 6554 C CD2 . TYR A 1 829 ? 24.177 59.319 -11.992 1.00 9.91 ? 829 TYR A CD2 1 ATOM 6555 C CE1 . TYR A 1 829 ? 24.316 57.504 -9.806 1.00 10.60 ? 829 TYR A CE1 1 ATOM 6556 C CE2 . TYR A 1 829 ? 23.071 58.497 -11.692 1.00 9.27 ? 829 TYR A CE2 1 ATOM 6557 C CZ . TYR A 1 829 ? 23.163 57.586 -10.570 1.00 8.79 ? 829 TYR A CZ 1 ATOM 6558 O OH . TYR A 1 829 ? 22.103 56.773 -10.252 1.00 10.55 ? 829 TYR A OH 1 ATOM 6559 N N . PRO A 1 830 ? 28.881 61.599 -10.079 1.00 8.81 ? 830 PRO A N 1 ATOM 6560 C CA . PRO A 1 830 ? 30.188 62.276 -10.238 1.00 6.01 ? 830 PRO A CA 1 ATOM 6561 C C . PRO A 1 830 ? 30.675 62.012 -11.677 1.00 7.18 ? 830 PRO A C 1 ATOM 6562 O O . PRO A 1 830 ? 30.454 60.942 -12.230 1.00 6.86 ? 830 PRO A O 1 ATOM 6563 C CB . PRO A 1 830 ? 31.097 61.534 -9.229 1.00 8.95 ? 830 PRO A CB 1 ATOM 6564 C CG . PRO A 1 830 ? 30.160 60.801 -8.305 1.00 10.10 ? 830 PRO A CG 1 ATOM 6565 C CD . PRO A 1 830 ? 28.842 60.590 -8.992 1.00 8.95 ? 830 PRO A CD 1 ATOM 6566 N N . ILE A 1 831 ? 31.295 63.018 -12.255 1.00 6.57 ? 831 ILE A N 1 ATOM 6567 C CA . ILE A 1 831 ? 31.951 62.921 -13.549 1.00 6.58 ? 831 ILE A CA 1 ATOM 6568 C C . ILE A 1 831 ? 33.380 63.235 -13.234 1.00 8.24 ? 831 ILE A C 1 ATOM 6569 O O . ILE A 1 831 ? 33.913 64.275 -13.622 1.00 10.10 ? 831 ILE A O 1 ATOM 6570 C CB . ILE A 1 831 ? 31.349 63.898 -14.600 1.00 7.12 ? 831 ILE A CB 1 ATOM 6571 C CG1 . ILE A 1 831 ? 29.802 63.961 -14.586 1.00 6.65 ? 831 ILE A CG1 1 ATOM 6572 C CG2 . ILE A 1 831 ? 31.869 63.464 -15.969 1.00 9.09 ? 831 ILE A CG2 1 ATOM 6573 C CD1 . ILE A 1 831 ? 29.101 62.583 -14.928 1.00 9.49 ? 831 ILE A CD1 1 ATOM 6574 N N . PRO A 1 832 ? 34.125 62.236 -12.648 1.00 7.01 ? 832 PRO A N 1 ATOM 6575 C CA . PRO A 1 832 ? 35.512 62.584 -12.322 1.00 7.66 ? 832 PRO A CA 1 ATOM 6576 C C . PRO A 1 832 ? 36.425 62.776 -13.499 1.00 6.98 ? 832 PRO A C 1 ATOM 6577 O O . PRO A 1 832 ? 37.339 63.583 -13.392 1.00 9.25 ? 832 PRO A O 1 ATOM 6578 C CB . PRO A 1 832 ? 35.940 61.512 -11.266 1.00 6.13 ? 832 PRO A CB 1 ATOM 6579 C CG . PRO A 1 832 ? 34.966 60.370 -11.467 1.00 9.00 ? 832 PRO A CG 1 ATOM 6580 C CD . PRO A 1 832 ? 33.668 61.010 -11.962 1.00 6.82 ? 832 PRO A CD 1 ATOM 6581 N N . SER A 1 833 ? 36.128 62.108 -14.613 1.00 9.47 ? 833 SER A N 1 ATOM 6582 C CA . SER A 1 833 ? 36.947 62.202 -15.842 1.00 8.12 ? 833 SER A CA 1 ATOM 6583 C C . SER A 1 833 ? 36.158 62.070 -17.130 1.00 8.71 ? 833 SER A C 1 ATOM 6584 O O . SER A 1 833 ? 36.699 62.404 -18.168 1.00 8.01 ? 833 SER A O 1 ATOM 6585 C CB . SER A 1 833 ? 37.981 61.067 -15.951 1.00 11.39 ? 833 SER A CB 1 ATOM 6586 O OG . SER A 1 833 ? 38.632 60.983 -14.733 1.00 22.84 ? 833 SER A OG 1 ATOM 6587 N N . GLY A 1 834 ? 34.925 61.548 -17.111 1.00 7.41 ? 834 GLY A N 1 ATOM 6588 C CA . GLY A 1 834 ? 34.248 61.449 -18.390 1.00 8.44 ? 834 GLY A CA 1 ATOM 6589 C C . GLY A 1 834 ? 32.888 60.831 -18.300 1.00 7.76 ? 834 GLY A C 1 ATOM 6590 O O . GLY A 1 834 ? 32.509 60.206 -17.289 1.00 9.54 ? 834 GLY A O 1 ATOM 6591 N N . MET A 1 835 ? 32.151 60.923 -19.425 1.00 7.28 ? 835 MET A N 1 ATOM 6592 C CA . MET A 1 835 ? 30.778 60.401 -19.451 1.00 7.30 ? 835 MET A CA 1 ATOM 6593 C C . MET A 1 835 ? 30.389 60.222 -20.892 1.00 8.34 ? 835 MET A C 1 ATOM 6594 O O . MET A 1 835 ? 31.012 60.859 -21.793 1.00 9.04 ? 835 MET A O 1 ATOM 6595 C CB . MET A 1 835 ? 29.792 61.409 -18.761 1.00 9.03 ? 835 MET A CB 1 ATOM 6596 C CG . MET A 1 835 ? 29.686 62.769 -19.499 1.00 11.36 ? 835 MET A CG 1 ATOM 6597 S SD . MET A 1 835 ? 28.748 64.070 -18.635 1.00 13.31 ? 835 MET A SD 1 ATOM 6598 C CE . MET A 1 835 ? 27.262 63.300 -18.324 1.00 14.95 ? 835 MET A CE 1 ATOM 6599 N N . PHE A 1 836 ? 29.435 59.319 -21.153 1.00 8.56 ? 836 PHE A N 1 ATOM 6600 C CA . PHE A 1 836 ? 28.976 59.154 -22.544 1.00 9.96 ? 836 PHE A CA 1 ATOM 6601 C C . PHE A 1 836 ? 27.608 58.567 -22.608 1.00 11.53 ? 836 PHE A C 1 ATOM 6602 O O . PHE A 1 836 ? 27.056 58.078 -21.615 1.00 10.28 ? 836 PHE A O 1 ATOM 6603 C CB . PHE A 1 836 ? 29.961 58.330 -23.413 1.00 8.56 ? 836 PHE A CB 1 ATOM 6604 C CG . PHE A 1 836 ? 30.180 56.844 -22.966 1.00 9.39 ? 836 PHE A CG 1 ATOM 6605 C CD1 . PHE A 1 836 ? 29.350 55.792 -23.447 1.00 8.76 ? 836 PHE A CD1 1 ATOM 6606 C CD2 . PHE A 1 836 ? 31.279 56.469 -22.162 1.00 7.69 ? 836 PHE A CD2 1 ATOM 6607 C CE1 . PHE A 1 836 ? 29.619 54.424 -23.148 1.00 12.50 ? 836 PHE A CE1 1 ATOM 6608 C CE2 . PHE A 1 836 ? 31.546 55.070 -21.868 1.00 10.02 ? 836 PHE A CE2 1 ATOM 6609 C CZ . PHE A 1 836 ? 30.720 54.055 -22.360 1.00 11.99 ? 836 PHE A CZ 1 ATOM 6610 N N . ILE A 1 837 ? 27.031 58.704 -23.802 1.00 9.86 ? 837 ILE A N 1 ATOM 6611 C CA . ILE A 1 837 ? 25.728 58.109 -24.154 1.00 9.92 ? 837 ILE A CA 1 ATOM 6612 C C . ILE A 1 837 ? 25.923 57.487 -25.505 1.00 11.42 ? 837 ILE A C 1 ATOM 6613 O O . ILE A 1 837 ? 26.804 57.928 -26.319 1.00 11.06 ? 837 ILE A O 1 ATOM 6614 C CB . ILE A 1 837 ? 24.605 59.121 -24.252 1.00 11.81 ? 837 ILE A CB 1 ATOM 6615 C CG1 . ILE A 1 837 ? 25.042 60.360 -25.029 1.00 11.27 ? 837 ILE A CG1 1 ATOM 6616 C CG2 . ILE A 1 837 ? 24.100 59.443 -22.876 1.00 11.26 ? 837 ILE A CG2 1 ATOM 6617 C CD1 . ILE A 1 837 ? 23.811 61.218 -25.600 1.00 12.96 ? 837 ILE A CD1 1 ATOM 6618 N N . GLU A 1 838 ? 25.114 56.456 -25.794 1.00 10.33 ? 838 GLU A N 1 ATOM 6619 C CA . GLU A 1 838 ? 25.223 55.798 -27.082 1.00 11.88 ? 838 GLU A CA 1 ATOM 6620 C C . GLU A 1 838 ? 23.910 55.070 -27.408 1.00 9.58 ? 838 GLU A C 1 ATOM 6621 O O . GLU A 1 838 ? 23.031 54.860 -26.580 1.00 11.06 ? 838 GLU A O 1 ATOM 6622 C CB . GLU A 1 838 ? 26.379 54.766 -27.058 1.00 11.84 ? 838 GLU A CB 1 ATOM 6623 C CG . GLU A 1 838 ? 26.137 53.616 -26.057 1.00 13.07 ? 838 GLU A CG 1 ATOM 6624 C CD . GLU A 1 838 ? 27.264 52.663 -25.978 1.00 13.93 ? 838 GLU A CD 1 ATOM 6625 O OE1 . GLU A 1 838 ? 28.300 52.877 -26.611 1.00 17.08 ? 838 GLU A OE1 1 ATOM 6626 O OE2 . GLU A 1 838 ? 27.134 51.628 -25.293 1.00 17.08 ? 838 GLU A OE2 1 ATOM 6627 N N . ASP A 1 839 ? 23.784 54.752 -28.692 1.00 13.23 ? 839 ASP A N 1 ATOM 6628 C CA . ASP A 1 839 ? 22.686 53.901 -29.088 1.00 12.96 ? 839 ASP A CA 1 ATOM 6629 C C . ASP A 1 839 ? 23.387 52.843 -29.920 1.00 15.08 ? 839 ASP A C 1 ATOM 6630 O O . ASP A 1 839 ? 24.578 52.645 -29.793 1.00 17.66 ? 839 ASP A O 1 ATOM 6631 C CB . ASP A 1 839 ? 21.565 54.641 -29.862 1.00 13.72 ? 839 ASP A CB 1 ATOM 6632 C CG . ASP A 1 839 ? 22.049 55.371 -31.129 1.00 14.15 ? 839 ASP A CG 1 ATOM 6633 O OD1 . ASP A 1 839 ? 23.076 54.983 -31.736 1.00 15.84 ? 839 ASP A OD1 1 ATOM 6634 O OD2 . ASP A 1 839 ? 21.346 56.357 -31.493 1.00 16.25 ? 839 ASP A OD2 1 ATOM 6635 N N . ALA A 1 840 ? 22.672 52.121 -30.772 1.00 16.26 ? 840 ALA A N 1 ATOM 6636 C CA . ALA A 1 840 ? 23.333 51.069 -31.516 1.00 14.30 ? 840 ALA A CA 1 ATOM 6637 C C . ALA A 1 840 ? 24.406 51.540 -32.466 1.00 15.22 ? 840 ALA A C 1 ATOM 6638 O O . ALA A 1 840 ? 25.378 50.853 -32.679 1.00 17.11 ? 840 ALA A O 1 ATOM 6639 C CB . ALA A 1 840 ? 22.278 50.233 -32.275 1.00 17.50 ? 840 ALA A CB 1 ATOM 6640 N N . ASN A 1 841 ? 24.300 52.762 -32.968 1.00 15.01 ? 841 ASN A N 1 ATOM 6641 C CA . ASN A 1 841 ? 25.257 53.203 -33.978 1.00 15.19 ? 841 ASN A CA 1 ATOM 6642 C C . ASN A 1 841 ? 26.175 54.344 -33.629 1.00 16.04 ? 841 ASN A C 1 ATOM 6643 O O . ASN A 1 841 ? 27.278 54.447 -34.190 1.00 14.58 ? 841 ASN A O 1 ATOM 6644 C CB . ASN A 1 841 ? 24.516 53.600 -35.275 1.00 16.35 ? 841 ASN A CB 1 ATOM 6645 C CG . ASN A 1 841 ? 23.710 52.452 -35.862 1.00 17.90 ? 841 ASN A CG 1 ATOM 6646 O OD1 . ASN A 1 841 ? 24.238 51.366 -36.106 1.00 16.84 ? 841 ASN A OD1 1 ATOM 6647 N ND2 . ASN A 1 841 ? 22.433 52.694 -36.101 1.00 20.48 ? 841 ASN A ND2 1 ATOM 6648 N N . THR A 1 842 ? 25.750 55.163 -32.671 1.00 15.22 ? 842 THR A N 1 ATOM 6649 C CA . THR A 1 842 ? 26.479 56.386 -32.387 1.00 15.07 ? 842 THR A CA 1 ATOM 6650 C C . THR A 1 842 ? 26.767 56.617 -30.909 1.00 14.02 ? 842 THR A C 1 ATOM 6651 O O . THR A 1 842 ? 25.914 56.296 -30.064 1.00 14.23 ? 842 THR A O 1 ATOM 6652 C CB . THR A 1 842 ? 25.662 57.587 -32.885 1.00 14.75 ? 842 THR A CB 1 ATOM 6653 O OG1 . THR A 1 842 ? 25.196 57.337 -34.246 1.00 15.83 ? 842 THR A OG1 1 ATOM 6654 C CG2 . THR A 1 842 ? 26.500 58.862 -32.828 1.00 13.80 ? 842 THR A CG2 1 ATOM 6655 N N . ARG A 1 843 ? 27.938 57.170 -30.594 1.00 13.42 ? 843 ARG A N 1 ATOM 6656 C CA . ARG A 1 843 ? 28.278 57.473 -29.213 1.00 12.83 ? 843 ARG A CA 1 ATOM 6657 C C . ARG A 1 843 ? 28.850 58.884 -29.117 1.00 12.55 ? 843 ARG A C 1 ATOM 6658 O O . ARG A 1 843 ? 29.586 59.376 -30.032 1.00 12.95 ? 843 ARG A O 1 ATOM 6659 C CB . ARG A 1 843 ? 29.330 56.480 -28.703 1.00 12.61 ? 843 ARG A CB 1 ATOM 6660 C CG . ARG A 1 843 ? 29.816 56.783 -27.242 1.00 12.84 ? 843 ARG A CG 1 ATOM 6661 C CD . ARG A 1 843 ? 30.996 55.877 -26.825 1.00 10.58 ? 843 ARG A CD 1 ATOM 6662 N NE . ARG A 1 843 ? 30.565 54.527 -26.499 1.00 12.26 ? 843 ARG A NE 1 ATOM 6663 C CZ . ARG A 1 843 ? 31.356 53.626 -25.892 1.00 11.04 ? 843 ARG A CZ 1 ATOM 6664 N NH1 . ARG A 1 843 ? 32.612 53.951 -25.568 1.00 12.47 ? 843 ARG A NH1 1 ATOM 6665 N NH2 . ARG A 1 843 ? 30.902 52.421 -25.633 1.00 13.02 ? 843 ARG A NH2 1 ATOM 6666 N N . LEU A 1 844 ? 28.504 59.571 -28.023 1.00 11.81 ? 844 LEU A N 1 ATOM 6667 C CA . LEU A 1 844 ? 29.062 60.892 -27.798 1.00 10.61 ? 844 LEU A CA 1 ATOM 6668 C C . LEU A 1 844 ? 29.706 60.789 -26.410 1.00 10.42 ? 844 LEU A C 1 ATOM 6669 O O . LEU A 1 844 ? 29.055 60.471 -25.423 1.00 11.57 ? 844 LEU A O 1 ATOM 6670 C CB . LEU A 1 844 ? 27.996 61.978 -27.787 1.00 11.49 ? 844 LEU A CB 1 ATOM 6671 C CG . LEU A 1 844 ? 28.589 63.405 -27.625 1.00 9.02 ? 844 LEU A CG 1 ATOM 6672 C CD1 . LEU A 1 844 ? 29.464 63.734 -28.891 1.00 12.60 ? 844 LEU A CD1 1 ATOM 6673 C CD2 . LEU A 1 844 ? 27.506 64.433 -27.354 1.00 12.68 ? 844 LEU A CD2 1 ATOM 6674 N N . THR A 1 845 ? 30.995 61.082 -26.354 1.00 10.55 ? 845 THR A N 1 ATOM 6675 C CA . THR A 1 845 ? 31.725 61.007 -25.092 1.00 10.74 ? 845 THR A CA 1 ATOM 6676 C C . THR A 1 845 ? 32.302 62.379 -24.776 1.00 9.91 ? 845 THR A C 1 ATOM 6677 O O . THR A 1 845 ? 32.911 63.003 -25.652 1.00 10.46 ? 845 THR A O 1 ATOM 6678 C CB . THR A 1 845 ? 32.924 60.024 -25.182 1.00 10.80 ? 845 THR A CB 1 ATOM 6679 O OG1 . THR A 1 845 ? 32.512 58.713 -25.594 1.00 11.73 ? 845 THR A OG1 1 ATOM 6680 C CG2 . THR A 1 845 ? 33.621 59.943 -23.797 1.00 9.12 ? 845 THR A CG2 1 ATOM 6681 N N . LEU A 1 846 ? 32.124 62.829 -23.548 1.00 9.09 ? 846 LEU A N 1 ATOM 6682 C CA . LEU A 1 846 ? 32.681 64.113 -23.057 1.00 10.36 ? 846 LEU A CA 1 ATOM 6683 C C . LEU A 1 846 ? 33.731 63.778 -22.011 1.00 10.38 ? 846 LEU A C 1 ATOM 6684 O O . LEU A 1 846 ? 33.376 63.174 -20.997 1.00 9.81 ? 846 LEU A O 1 ATOM 6685 C CB . LEU A 1 846 ? 31.603 64.978 -22.434 1.00 10.70 ? 846 LEU A CB 1 ATOM 6686 C CG . LEU A 1 846 ? 32.002 66.345 -21.888 1.00 10.92 ? 846 LEU A CG 1 ATOM 6687 C CD1 . LEU A 1 846 ? 32.403 67.275 -23.053 1.00 12.75 ? 846 LEU A CD1 1 ATOM 6688 C CD2 . LEU A 1 846 ? 30.889 66.957 -21.115 1.00 13.03 ? 846 LEU A CD2 1 ATOM 6689 N N . LEU A 1 847 ? 35.000 64.103 -22.277 1.00 9.50 ? 847 LEU A N 1 ATOM 6690 C CA . LEU A 1 847 ? 36.110 63.824 -21.300 1.00 9.01 ? 847 LEU A CA 1 ATOM 6691 C C . LEU A 1 847 ? 36.358 65.150 -20.591 1.00 9.20 ? 847 LEU A C 1 ATOM 6692 O O . LEU A 1 847 ? 36.236 66.208 -21.197 1.00 8.58 ? 847 LEU A O 1 ATOM 6693 C CB . LEU A 1 847 ? 37.382 63.348 -22.027 1.00 9.20 ? 847 LEU A CB 1 ATOM 6694 C CG . LEU A 1 847 ? 37.388 62.027 -22.788 1.00 8.86 ? 847 LEU A CG 1 ATOM 6695 C CD1 . LEU A 1 847 ? 36.731 60.953 -21.944 1.00 9.53 ? 847 LEU A CD1 1 ATOM 6696 C CD2 . LEU A 1 847 ? 36.723 62.145 -24.178 1.00 9.35 ? 847 LEU A CD2 1 ATOM 6697 N N . THR A 1 848 ? 36.731 65.120 -19.299 1.00 8.05 ? 848 THR A N 1 ATOM 6698 C CA . THR A 1 848 ? 36.941 66.330 -18.467 1.00 9.18 ? 848 THR A CA 1 ATOM 6699 C C . THR A 1 848 ? 38.351 66.403 -17.882 1.00 10.72 ? 848 THR A C 1 ATOM 6700 O O . THR A 1 848 ? 39.034 65.336 -17.687 1.00 10.43 ? 848 THR A O 1 ATOM 6701 C CB . THR A 1 848 ? 35.947 66.407 -17.253 1.00 11.06 ? 848 THR A CB 1 ATOM 6702 O OG1 . THR A 1 848 ? 36.365 65.411 -16.271 1.00 12.38 ? 848 THR A OG1 1 ATOM 6703 C CG2 . THR A 1 848 ? 34.517 66.136 -17.688 1.00 10.43 ? 848 THR A CG2 1 ATOM 6704 N N . GLY A 1 849 ? 38.793 67.624 -17.622 1.00 10.28 ? 849 GLY A N 1 ATOM 6705 C CA . GLY A 1 849 ? 40.105 67.834 -17.054 1.00 10.23 ? 849 GLY A CA 1 ATOM 6706 C C . GLY A 1 849 ? 39.936 68.201 -15.588 1.00 6.98 ? 849 GLY A C 1 ATOM 6707 O O . GLY A 1 849 ? 40.850 68.616 -14.896 1.00 7.17 ? 849 GLY A O 1 ATOM 6708 N N . GLN A 1 850 ? 38.740 67.942 -15.063 1.00 7.85 ? 850 GLN A N 1 ATOM 6709 C CA . GLN A 1 850 ? 38.377 68.258 -13.675 1.00 6.89 ? 850 GLN A CA 1 ATOM 6710 C C . GLN A 1 850 ? 37.085 67.519 -13.281 1.00 7.18 ? 850 GLN A C 1 ATOM 6711 O O . GLN A 1 850 ? 36.236 67.298 -14.121 1.00 6.85 ? 850 GLN A O 1 ATOM 6712 C CB . GLN A 1 850 ? 38.103 69.769 -13.502 1.00 8.19 ? 850 GLN A CB 1 ATOM 6713 C CG . GLN A 1 850 ? 36.981 70.370 -14.422 1.00 7.57 ? 850 GLN A CG 1 ATOM 6714 C CD . GLN A 1 850 ? 37.361 70.466 -15.885 1.00 10.10 ? 850 GLN A CD 1 ATOM 6715 O OE1 . GLN A 1 850 ? 38.470 70.902 -16.227 1.00 9.01 ? 850 GLN A OE1 1 ATOM 6716 N NE2 . GLN A 1 850 ? 36.421 70.113 -16.774 1.00 9.34 ? 850 GLN A NE2 1 ATOM 6717 N N . PRO A 1 851 ? 36.962 67.131 -12.018 1.00 6.57 ? 851 PRO A N 1 ATOM 6718 C CA . PRO A 1 851 ? 35.704 66.419 -11.624 1.00 6.01 ? 851 PRO A CA 1 ATOM 6719 C C . PRO A 1 851 ? 34.570 67.414 -11.425 1.00 7.26 ? 851 PRO A C 1 ATOM 6720 O O . PRO A 1 851 ? 34.762 68.462 -10.799 1.00 7.32 ? 851 PRO A O 1 ATOM 6721 C CB . PRO A 1 851 ? 36.123 65.693 -10.312 1.00 7.77 ? 851 PRO A CB 1 ATOM 6722 C CG . PRO A 1 851 ? 37.185 66.689 -9.679 1.00 6.08 ? 851 PRO A CG 1 ATOM 6723 C CD . PRO A 1 851 ? 37.977 67.183 -10.944 1.00 6.45 ? 851 PRO A CD 1 ATOM 6724 N N . LEU A 1 852 ? 33.412 67.071 -12.002 1.00 6.95 ? 852 LEU A N 1 ATOM 6725 C CA . LEU A 1 852 ? 32.216 67.927 -11.864 1.00 9.09 ? 852 LEU A CA 1 ATOM 6726 C C . LEU A 1 852 ? 31.009 66.974 -11.786 1.00 8.80 ? 852 LEU A C 1 ATOM 6727 O O . LEU A 1 852 ? 31.137 65.767 -12.027 1.00 11.79 ? 852 LEU A O 1 ATOM 6728 C CB . LEU A 1 852 ? 32.108 68.839 -13.119 1.00 8.80 ? 852 LEU A CB 1 ATOM 6729 C CG . LEU A 1 852 ? 33.254 69.884 -13.287 1.00 6.57 ? 852 LEU A CG 1 ATOM 6730 C CD1 . LEU A 1 852 ? 33.221 70.523 -14.719 1.00 10.43 ? 852 LEU A CD1 1 ATOM 6731 C CD2 . LEU A 1 852 ? 33.126 70.899 -12.172 1.00 7.66 ? 852 LEU A CD2 1 ATOM 6732 N N . GLY A 1 853 ? 29.827 67.506 -11.455 1.00 8.07 ? 853 GLY A N 1 ATOM 6733 C CA . GLY A 1 853 ? 28.638 66.683 -11.400 1.00 8.53 ? 853 GLY A CA 1 ATOM 6734 C C . GLY A 1 853 ? 27.882 66.696 -12.705 1.00 8.18 ? 853 GLY A C 1 ATOM 6735 O O . GLY A 1 853 ? 27.915 67.664 -13.439 1.00 8.24 ? 853 GLY A O 1 ATOM 6736 N N . GLY A 1 854 ? 27.183 65.627 -13.034 1.00 7.57 ? 854 GLY A N 1 ATOM 6737 C CA . GLY A 1 854 ? 26.492 65.620 -14.328 1.00 8.45 ? 854 GLY A CA 1 ATOM 6738 C C . GLY A 1 854 ? 25.464 64.508 -14.442 1.00 9.49 ? 854 GLY A C 1 ATOM 6739 O O . GLY A 1 854 ? 25.351 63.635 -13.545 1.00 10.72 ? 854 GLY A O 1 ATOM 6740 N N . SER A 1 855 ? 24.756 64.491 -15.567 1.00 11.59 ? 855 SER A N 1 ATOM 6741 C CA . SER A 1 855 ? 23.745 63.470 -15.778 1.00 10.70 ? 855 SER A CA 1 ATOM 6742 C C . SER A 1 855 ? 23.336 63.421 -17.245 1.00 12.39 ? 855 SER A C 1 ATOM 6743 O O . SER A 1 855 ? 23.973 64.048 -18.117 1.00 11.62 ? 855 SER A O 1 ATOM 6744 C CB . SER A 1 855 ? 22.541 63.813 -14.914 1.00 12.54 ? 855 SER A CB 1 ATOM 6745 O OG . SER A 1 855 ? 21.505 62.844 -15.089 1.00 9.27 ? 855 SER A OG 1 ATOM 6746 N N . SER A 1 856 ? 22.296 62.640 -17.506 1.00 11.95 ? 856 SER A N 1 ATOM 6747 C CA . SER A 1 856 ? 21.662 62.563 -18.834 1.00 11.52 ? 856 SER A CA 1 ATOM 6748 C C . SER A 1 856 ? 20.201 62.569 -18.401 1.00 9.84 ? 856 SER A C 1 ATOM 6749 O O . SER A 1 856 ? 19.652 61.516 -18.021 1.00 10.95 ? 856 SER A O 1 ATOM 6750 C CB . SER A 1 856 ? 21.949 61.253 -19.559 1.00 10.96 ? 856 SER A CB 1 ATOM 6751 O OG . SER A 1 856 ? 21.174 61.239 -20.777 1.00 10.31 ? 856 SER A OG 1 ATOM 6752 N N . LEU A 1 857 ? 19.548 63.721 -18.428 1.00 12.03 ? 857 LEU A N 1 ATOM 6753 C CA . LEU A 1 857 ? 18.182 63.767 -17.895 1.00 12.24 ? 857 LEU A CA 1 ATOM 6754 C C . LEU A 1 857 ? 17.068 63.474 -18.884 1.00 12.45 ? 857 LEU A C 1 ATOM 6755 O O . LEU A 1 857 ? 15.909 63.413 -18.498 1.00 13.27 ? 857 LEU A O 1 ATOM 6756 C CB . LEU A 1 857 ? 17.955 65.109 -17.187 1.00 11.38 ? 857 LEU A CB 1 ATOM 6757 C CG . LEU A 1 857 ? 18.802 65.436 -15.946 1.00 13.06 ? 857 LEU A CG 1 ATOM 6758 C CD1 . LEU A 1 857 ? 18.553 66.872 -15.613 1.00 13.48 ? 857 LEU A CD1 1 ATOM 6759 C CD2 . LEU A 1 857 ? 18.450 64.547 -14.741 1.00 12.30 ? 857 LEU A CD2 1 ATOM 6760 N N . ALA A 1 858 ? 17.450 63.195 -20.118 1.00 12.34 ? 858 ALA A N 1 ATOM 6761 C CA . ALA A 1 858 ? 16.531 62.833 -21.220 1.00 13.49 ? 858 ALA A CA 1 ATOM 6762 C C . ALA A 1 858 ? 17.361 62.146 -22.271 1.00 13.23 ? 858 ALA A C 1 ATOM 6763 O O . ALA A 1 858 ? 18.572 62.426 -22.438 1.00 13.29 ? 858 ALA A O 1 ATOM 6764 C CB . ALA A 1 858 ? 15.868 64.098 -21.889 1.00 13.21 ? 858 ALA A CB 1 ATOM 6765 N N . SER A 1 859 ? 16.749 61.251 -23.026 1.00 14.39 ? 859 SER A N 1 ATOM 6766 C CA . SER A 1 859 ? 17.407 60.552 -24.099 1.00 13.30 ? 859 SER A CA 1 ATOM 6767 C C . SER A 1 859 ? 18.155 61.532 -25.025 1.00 13.42 ? 859 SER A C 1 ATOM 6768 O O . SER A 1 859 ? 17.618 62.612 -25.313 1.00 14.56 ? 859 SER A O 1 ATOM 6769 C CB . SER A 1 859 ? 16.327 59.808 -24.912 1.00 13.41 ? 859 SER A CB 1 ATOM 6770 O OG . SER A 1 859 ? 16.883 58.998 -25.921 1.00 16.56 ? 859 SER A OG 1 ATOM 6771 N N . GLY A 1 860 ? 19.390 61.194 -25.389 1.00 12.30 ? 860 GLY A N 1 ATOM 6772 C CA . GLY A 1 860 ? 20.195 62.022 -26.272 1.00 12.18 ? 860 GLY A CA 1 ATOM 6773 C C . GLY A 1 860 ? 20.913 63.215 -25.631 1.00 12.52 ? 860 GLY A C 1 ATOM 6774 O O . GLY A 1 860 ? 21.652 63.948 -26.326 1.00 12.36 ? 860 GLY A O 1 ATOM 6775 N N . GLU A 1 861 ? 20.727 63.412 -24.326 1.00 10.75 ? 861 GLU A N 1 ATOM 6776 C CA . GLU A 1 861 ? 21.383 64.509 -23.598 1.00 11.43 ? 861 GLU A CA 1 ATOM 6777 C C . GLU A 1 861 ? 22.548 64.125 -22.663 1.00 11.63 ? 861 GLU A C 1 ATOM 6778 O O . GLU A 1 861 ? 22.640 62.973 -22.122 1.00 11.90 ? 861 GLU A O 1 ATOM 6779 C CB . GLU A 1 861 ? 20.409 65.280 -22.717 1.00 13.84 ? 861 GLU A CB 1 ATOM 6780 C CG . GLU A 1 861 ? 19.241 65.865 -23.490 1.00 15.49 ? 861 GLU A CG 1 ATOM 6781 C CD . GLU A 1 861 ? 18.361 66.713 -22.624 1.00 18.40 ? 861 GLU A CD 1 ATOM 6782 O OE1 . GLU A 1 861 ? 18.568 66.751 -21.391 1.00 16.64 ? 861 GLU A OE1 1 ATOM 6783 O OE2 . GLU A 1 861 ? 17.402 67.363 -23.142 1.00 17.90 ? 861 GLU A OE2 1 ATOM 6784 N N . LEU A 1 862 ? 23.453 65.080 -22.537 1.00 13.37 ? 862 LEU A N 1 ATOM 6785 C CA . LEU A 1 862 ? 24.536 64.946 -21.545 1.00 13.13 ? 862 LEU A CA 1 ATOM 6786 C C . LEU A 1 862 ? 24.598 66.318 -20.915 1.00 10.42 ? 862 LEU A C 1 ATOM 6787 O O . LEU A 1 862 ? 24.392 67.341 -21.614 1.00 11.48 ? 862 LEU A O 1 ATOM 6788 C CB . LEU A 1 862 ? 25.888 64.717 -22.219 1.00 13.35 ? 862 LEU A CB 1 ATOM 6789 C CG . LEU A 1 862 ? 26.182 63.331 -22.749 1.00 15.06 ? 862 LEU A CG 1 ATOM 6790 C CD1 . LEU A 1 862 ? 27.539 63.331 -23.487 1.00 17.57 ? 862 LEU A CD1 1 ATOM 6791 C CD2 . LEU A 1 862 ? 26.235 62.325 -21.582 1.00 15.15 ? 862 LEU A CD2 1 ATOM 6792 N N . GLU A 1 863 ? 24.827 66.414 -19.601 1.00 9.75 ? 863 GLU A N 1 ATOM 6793 C CA . GLU A 1 863 ? 25.001 67.728 -18.997 1.00 10.30 ? 863 GLU A CA 1 ATOM 6794 C C . GLU A 1 863 ? 25.958 67.649 -17.835 1.00 11.48 ? 863 GLU A C 1 ATOM 6795 O O . GLU A 1 863 ? 26.123 66.555 -17.254 1.00 9.99 ? 863 GLU A O 1 ATOM 6796 C CB . GLU A 1 863 ? 23.696 68.340 -18.555 1.00 10.08 ? 863 GLU A CB 1 ATOM 6797 C CG . GLU A 1 863 ? 23.121 67.800 -17.268 1.00 10.68 ? 863 GLU A CG 1 ATOM 6798 C CD . GLU A 1 863 ? 21.797 68.487 -16.947 1.00 13.07 ? 863 GLU A CD 1 ATOM 6799 O OE1 . GLU A 1 863 ? 20.906 68.468 -17.873 1.00 13.76 ? 863 GLU A OE1 1 ATOM 6800 O OE2 . GLU A 1 863 ? 21.677 69.035 -15.821 1.00 11.31 ? 863 GLU A OE2 1 ATOM 6801 N N . ILE A 1 864 ? 26.665 68.749 -17.596 1.00 9.41 ? 864 ILE A N 1 ATOM 6802 C CA . ILE A 1 864 ? 27.708 68.775 -16.549 1.00 10.92 ? 864 ILE A CA 1 ATOM 6803 C C . ILE A 1 864 ? 27.739 70.161 -16.006 1.00 10.06 ? 864 ILE A C 1 ATOM 6804 O O . ILE A 1 864 ? 27.816 71.188 -16.740 1.00 10.27 ? 864 ILE A O 1 ATOM 6805 C CB . ILE A 1 864 ? 29.080 68.368 -17.172 1.00 10.50 ? 864 ILE A CB 1 ATOM 6806 C CG1 . ILE A 1 864 ? 30.189 68.352 -16.121 1.00 12.05 ? 864 ILE A CG1 1 ATOM 6807 C CG2 . ILE A 1 864 ? 29.467 69.277 -18.319 1.00 14.00 ? 864 ILE A CG2 1 ATOM 6808 C CD1 . ILE A 1 864 ? 31.292 67.348 -16.640 1.00 12.79 ? 864 ILE A CD1 1 ATOM 6809 N N . MET A 1 865 ? 27.682 70.211 -14.702 1.00 8.56 ? 865 MET A N 1 ATOM 6810 C CA . MET A 1 865 ? 27.667 71.465 -13.974 1.00 8.68 ? 865 MET A CA 1 ATOM 6811 C C . MET A 1 865 ? 29.028 72.143 -14.005 1.00 8.61 ? 865 MET A C 1 ATOM 6812 O O . MET A 1 865 ? 30.075 71.492 -13.890 1.00 8.83 ? 865 MET A O 1 ATOM 6813 C CB . MET A 1 865 ? 27.221 71.245 -12.538 1.00 8.93 ? 865 MET A CB 1 ATOM 6814 C CG . MET A 1 865 ? 26.597 72.439 -11.860 1.00 7.83 ? 865 MET A CG 1 ATOM 6815 S SD . MET A 1 865 ? 24.970 72.851 -12.558 1.00 12.02 ? 865 MET A SD 1 ATOM 6816 C CE . MET A 1 865 ? 23.930 71.617 -11.572 1.00 10.41 ? 865 MET A CE 1 ATOM 6817 N N . GLN A 1 866 ? 29.018 73.455 -14.167 1.00 8.96 ? 866 GLN A N 1 ATOM 6818 C CA . GLN A 1 866 ? 30.241 74.285 -14.297 1.00 8.43 ? 866 GLN A CA 1 ATOM 6819 C C . GLN A 1 866 ? 30.643 74.936 -12.975 1.00 8.07 ? 866 GLN A C 1 ATOM 6820 O O . GLN A 1 866 ? 31.818 74.903 -12.580 1.00 10.61 ? 866 GLN A O 1 ATOM 6821 C CB . GLN A 1 866 ? 29.992 75.331 -15.382 1.00 9.46 ? 866 GLN A CB 1 ATOM 6822 C CG . GLN A 1 866 ? 29.652 74.702 -16.736 1.00 10.22 ? 866 GLN A CG 1 ATOM 6823 C CD . GLN A 1 866 ? 30.716 73.726 -17.220 1.00 9.46 ? 866 GLN A CD 1 ATOM 6824 O OE1 . GLN A 1 866 ? 31.824 74.149 -17.595 1.00 10.01 ? 866 GLN A OE1 1 ATOM 6825 N NE2 . GLN A 1 866 ? 30.410 72.442 -17.218 1.00 10.31 ? 866 GLN A NE2 1 ATOM 6826 N N . ASP A 1 867 ? 29.681 75.569 -12.257 1.00 9.03 ? 867 ASP A N 1 ATOM 6827 C CA . ASP A 1 867 ? 29.895 76.189 -10.966 1.00 9.11 ? 867 ASP A CA 1 ATOM 6828 C C . ASP A 1 867 ? 28.541 76.438 -10.333 1.00 9.86 ? 867 ASP A C 1 ATOM 6829 O O . ASP A 1 867 ? 27.494 76.316 -11.012 1.00 9.71 ? 867 ASP A O 1 ATOM 6830 C CB . ASP A 1 867 ? 30.741 77.530 -11.070 1.00 9.14 ? 867 ASP A CB 1 ATOM 6831 C CG . ASP A 1 867 ? 31.387 77.944 -9.722 1.00 13.08 ? 867 ASP A CG 1 ATOM 6832 O OD1 . ASP A 1 867 ? 31.259 77.227 -8.709 1.00 11.03 ? 867 ASP A OD1 1 ATOM 6833 O OD2 . ASP A 1 867 ? 32.094 78.978 -9.674 1.00 13.55 ? 867 ASP A OD2 1 ATOM 6834 N N . ARG A 1 868 ? 28.549 76.673 -9.024 1.00 7.99 ? 868 ARG A N 1 ATOM 6835 C CA . ARG A 1 868 ? 27.329 76.883 -8.276 1.00 10.43 ? 868 ARG A CA 1 ATOM 6836 C C . ARG A 1 868 ? 27.640 77.894 -7.196 1.00 10.97 ? 868 ARG A C 1 ATOM 6837 O O . ARG A 1 868 ? 28.726 77.874 -6.581 1.00 12.86 ? 868 ARG A O 1 ATOM 6838 C CB . ARG A 1 868 ? 26.857 75.526 -7.686 1.00 9.76 ? 868 ARG A CB 1 ATOM 6839 C CG . ARG A 1 868 ? 27.861 74.776 -6.762 1.00 11.64 ? 868 ARG A CG 1 ATOM 6840 C CD . ARG A 1 868 ? 27.590 73.274 -6.863 1.00 8.63 ? 868 ARG A CD 1 ATOM 6841 N NE . ARG A 1 868 ? 26.229 72.990 -6.436 1.00 9.37 ? 868 ARG A NE 1 ATOM 6842 C CZ . ARG A 1 868 ? 25.865 72.672 -5.183 1.00 7.47 ? 868 ARG A CZ 1 ATOM 6843 N NH1 . ARG A 1 868 ? 26.727 72.530 -4.189 1.00 9.12 ? 868 ARG A NH1 1 ATOM 6844 N NH2 . ARG A 1 868 ? 24.545 72.557 -4.888 1.00 10.47 ? 868 ARG A NH2 1 ATOM 6845 N N . ARG A 1 869 ? 26.713 78.856 -7.003 1.00 12.71 ? 869 ARG A N 1 ATOM 6846 C CA . ARG A 1 869 ? 26.911 79.883 -5.961 1.00 13.34 ? 869 ARG A CA 1 ATOM 6847 C C . ARG A 1 869 ? 25.646 79.870 -5.109 1.00 14.45 ? 869 ARG A C 1 ATOM 6848 O O . ARG A 1 869 ? 24.573 80.069 -5.667 1.00 13.17 ? 869 ARG A O 1 ATOM 6849 C CB . ARG A 1 869 ? 27.153 81.232 -6.627 1.00 14.85 ? 869 ARG A CB 1 ATOM 6850 C CG . ARG A 1 869 ? 27.371 82.351 -5.622 1.00 15.74 ? 869 ARG A CG 1 ATOM 6851 C CD . ARG A 1 869 ? 27.630 83.670 -6.395 1.00 18.10 ? 869 ARG A CD 1 ATOM 6852 N NE . ARG A 1 869 ? 27.779 84.831 -5.497 1.00 18.62 ? 869 ARG A NE 1 ATOM 6853 C CZ . ARG A 1 869 ? 28.924 85.181 -4.918 1.00 20.67 ? 869 ARG A CZ 1 ATOM 6854 N NH1 . ARG A 1 869 ? 30.034 84.465 -5.156 1.00 18.83 ? 869 ARG A NH1 1 ATOM 6855 N NH2 . ARG A 1 869 ? 28.973 86.214 -4.065 1.00 21.58 ? 869 ARG A NH2 1 ATOM 6856 N N . LEU A 1 870 ? 25.789 79.619 -3.806 1.00 14.33 ? 870 LEU A N 1 ATOM 6857 C CA . LEU A 1 870 ? 24.627 79.380 -2.935 1.00 15.77 ? 870 LEU A CA 1 ATOM 6858 C C . LEU A 1 870 ? 24.646 80.247 -1.702 1.00 14.17 ? 870 LEU A C 1 ATOM 6859 O O . LEU A 1 870 ? 25.592 80.199 -0.939 1.00 14.21 ? 870 LEU A O 1 ATOM 6860 C CB . LEU A 1 870 ? 24.632 77.893 -2.529 1.00 16.45 ? 870 LEU A CB 1 ATOM 6861 C CG . LEU A 1 870 ? 24.713 77.037 -3.812 1.00 20.29 ? 870 LEU A CG 1 ATOM 6862 C CD1 . LEU A 1 870 ? 25.241 75.683 -3.452 1.00 20.40 ? 870 LEU A CD1 1 ATOM 6863 C CD2 . LEU A 1 870 ? 23.385 76.931 -4.517 1.00 18.61 ? 870 LEU A CD2 1 ATOM 6864 N N . ALA A 1 871 ? 23.572 81.021 -1.479 1.00 15.39 ? 871 ALA A N 1 ATOM 6865 C CA . ALA A 1 871 ? 23.577 81.930 -0.323 1.00 16.76 ? 871 ALA A CA 1 ATOM 6866 C C . ALA A 1 871 ? 23.198 81.315 1.018 1.00 18.08 ? 871 ALA A C 1 ATOM 6867 O O . ALA A 1 871 ? 23.353 81.953 2.059 1.00 18.49 ? 871 ALA A O 1 ATOM 6868 C CB . ALA A 1 871 ? 22.674 83.137 -0.599 1.00 17.53 ? 871 ALA A CB 1 ATOM 6869 N N . SER A 1 872 ? 22.705 80.081 1.008 1.00 16.52 ? 872 SER A N 1 ATOM 6870 C CA . SER A 1 872 ? 22.340 79.444 2.260 1.00 17.01 ? 872 SER A CA 1 ATOM 6871 C C . SER A 1 872 ? 23.165 78.240 2.593 1.00 16.64 ? 872 SER A C 1 ATOM 6872 O O . SER A 1 872 ? 23.788 77.624 1.715 1.00 17.03 ? 872 SER A O 1 ATOM 6873 C CB . SER A 1 872 ? 20.886 78.981 2.250 1.00 18.00 ? 872 SER A CB 1 ATOM 6874 O OG . SER A 1 872 ? 19.999 80.089 2.220 1.00 23.38 ? 872 SER A OG 1 ATOM 6875 N N . ASP A 1 873 ? 23.098 77.893 3.867 1.00 16.55 ? 873 ASP A N 1 ATOM 6876 C CA . ASP A 1 873 ? 23.771 76.714 4.438 1.00 17.74 ? 873 ASP A CA 1 ATOM 6877 C C . ASP A 1 873 ? 22.776 75.582 4.261 1.00 16.98 ? 873 ASP A C 1 ATOM 6878 O O . ASP A 1 873 ? 21.553 75.825 4.267 1.00 17.20 ? 873 ASP A O 1 ATOM 6879 C CB . ASP A 1 873 ? 24.028 76.935 5.922 1.00 15.61 ? 873 ASP A CB 1 ATOM 6880 C CG . ASP A 1 873 ? 24.534 75.696 6.616 1.00 17.82 ? 873 ASP A CG 1 ATOM 6881 O OD1 . ASP A 1 873 ? 25.624 75.199 6.239 1.00 19.12 ? 873 ASP A OD1 1 ATOM 6882 O OD2 . ASP A 1 873 ? 23.845 75.222 7.530 1.00 18.56 ? 873 ASP A OD2 1 ATOM 6883 N N . ASP A 1 874 ? 23.291 74.352 4.083 1.00 15.85 ? 874 ASP A N 1 ATOM 6884 C CA . ASP A 1 874 ? 22.413 73.183 3.876 1.00 14.21 ? 874 ASP A CA 1 ATOM 6885 C C . ASP A 1 874 ? 22.276 72.257 5.089 1.00 14.57 ? 874 ASP A C 1 ATOM 6886 O O . ASP A 1 874 ? 22.018 71.020 4.944 1.00 17.28 ? 874 ASP A O 1 ATOM 6887 C CB . ASP A 1 874 ? 22.812 72.374 2.653 1.00 12.28 ? 874 ASP A CB 1 ATOM 6888 C CG . ASP A 1 874 ? 24.319 72.028 2.590 1.00 13.27 ? 874 ASP A CG 1 ATOM 6889 O OD1 . ASP A 1 874 ? 25.117 72.366 3.505 1.00 15.68 ? 874 ASP A OD1 1 ATOM 6890 O OD2 . ASP A 1 874 ? 24.672 71.455 1.524 1.00 12.66 ? 874 ASP A OD2 1 ATOM 6891 N N . GLU A 1 875 ? 22.519 72.825 6.276 1.00 14.66 ? 875 GLU A N 1 ATOM 6892 C CA . GLU A 1 875 ? 22.294 72.156 7.553 1.00 16.35 ? 875 GLU A CA 1 ATOM 6893 C C . GLU A 1 875 ? 23.018 70.863 7.874 1.00 16.87 ? 875 GLU A C 1 ATOM 6894 O O . GLU A 1 875 ? 22.476 69.981 8.546 1.00 16.04 ? 875 GLU A O 1 ATOM 6895 C CB . GLU A 1 875 ? 20.804 71.900 7.742 1.00 21.42 ? 875 GLU A CB 1 ATOM 6896 C CG . GLU A 1 875 ? 19.980 73.083 7.355 1.00 26.83 ? 875 GLU A CG 1 ATOM 6897 C CD . GLU A 1 875 ? 18.888 73.353 8.336 1.00 31.70 ? 875 GLU A CD 1 ATOM 6898 O OE1 . GLU A 1 875 ? 19.164 73.348 9.568 1.00 34.80 ? 875 GLU A OE1 1 ATOM 6899 O OE2 . GLU A 1 875 ? 17.753 73.598 7.875 1.00 34.35 ? 875 GLU A OE2 1 ATOM 6900 N N . ARG A 1 876 ? 24.255 70.745 7.419 1.00 15.23 ? 876 ARG A N 1 ATOM 6901 C CA . ARG A 1 876 ? 25.027 69.577 7.697 1.00 16.81 ? 876 ARG A CA 1 ATOM 6902 C C . ARG A 1 876 ? 26.179 69.953 8.598 1.00 17.43 ? 876 ARG A C 1 ATOM 6903 O O . ARG A 1 876 ? 27.061 69.125 8.832 1.00 18.15 ? 876 ARG A O 1 ATOM 6904 C CB . ARG A 1 876 ? 25.515 68.938 6.379 1.00 14.27 ? 876 ARG A CB 1 ATOM 6905 C CG . ARG A 1 876 ? 24.365 68.337 5.463 1.00 13.42 ? 876 ARG A CG 1 ATOM 6906 C CD . ARG A 1 876 ? 23.479 67.328 6.268 1.00 14.48 ? 876 ARG A CD 1 ATOM 6907 N NE . ARG A 1 876 ? 22.452 66.621 5.491 1.00 16.03 ? 876 ARG A NE 1 ATOM 6908 C CZ . ARG A 1 876 ? 21.277 67.136 5.121 1.00 15.28 ? 876 ARG A CZ 1 ATOM 6909 N NH1 . ARG A 1 876 ? 20.980 68.390 5.392 1.00 12.91 ? 876 ARG A NH1 1 ATOM 6910 N NH2 . ARG A 1 876 ? 20.315 66.335 4.657 1.00 10.68 ? 876 ARG A NH2 1 ATOM 6911 N N . GLY A 1 877 ? 26.225 71.211 9.052 1.00 17.20 ? 877 GLY A N 1 ATOM 6912 C CA . GLY A 1 877 ? 27.277 71.621 9.966 1.00 16.99 ? 877 GLY A CA 1 ATOM 6913 C C . GLY A 1 877 ? 28.341 72.575 9.442 1.00 14.81 ? 877 GLY A C 1 ATOM 6914 O O . GLY A 1 877 ? 29.116 73.133 10.270 1.00 15.74 ? 877 GLY A O 1 ATOM 6915 N N . LEU A 1 878 ? 28.363 72.804 8.115 1.00 13.16 ? 878 LEU A N 1 ATOM 6916 C CA . LEU A 1 878 ? 29.353 73.692 7.501 1.00 13.72 ? 878 LEU A CA 1 ATOM 6917 C C . LEU A 1 878 ? 29.085 75.130 7.936 1.00 14.96 ? 878 LEU A C 1 ATOM 6918 O O . LEU A 1 878 ? 30.026 75.914 8.109 1.00 15.27 ? 878 LEU A O 1 ATOM 6919 C CB . LEU A 1 878 ? 29.361 73.589 5.972 1.00 14.09 ? 878 LEU A CB 1 ATOM 6920 C CG . LEU A 1 878 ? 30.268 74.607 5.244 1.00 13.32 ? 878 LEU A CG 1 ATOM 6921 C CD1 . LEU A 1 878 ? 31.787 74.555 5.691 1.00 15.88 ? 878 LEU A CD1 1 ATOM 6922 C CD2 . LEU A 1 878 ? 30.096 74.332 3.796 1.00 15.43 ? 878 LEU A CD2 1 ATOM 6923 N N . GLY A 1 879 ? 27.806 75.446 8.171 1.00 14.73 ? 879 GLY A N 1 ATOM 6924 C CA . GLY A 1 879 ? 27.438 76.769 8.655 1.00 19.07 ? 879 GLY A CA 1 ATOM 6925 C C . GLY A 1 879 ? 27.754 77.942 7.746 1.00 18.53 ? 879 GLY A C 1 ATOM 6926 O O . GLY A 1 879 ? 28.081 79.031 8.224 1.00 20.95 ? 879 GLY A O 1 ATOM 6927 N N . GLN A 1 880 ? 27.671 77.723 6.440 1.00 18.87 ? 880 GLN A N 1 ATOM 6928 C CA . GLN A 1 880 ? 27.866 78.757 5.450 1.00 16.90 ? 880 GLN A CA 1 ATOM 6929 C C . GLN A 1 880 ? 27.403 78.260 4.076 1.00 16.39 ? 880 GLN A C 1 ATOM 6930 O O . GLN A 1 880 ? 27.280 77.052 3.845 1.00 17.00 ? 880 GLN A O 1 ATOM 6931 C CB . GLN A 1 880 ? 29.367 79.232 5.400 1.00 17.15 ? 880 GLN A CB 1 ATOM 6932 C CG . GLN A 1 880 ? 30.390 78.233 4.767 1.00 16.63 ? 880 GLN A CG 1 ATOM 6933 C CD . GLN A 1 880 ? 31.692 78.911 4.250 1.00 13.42 ? 880 GLN A CD 1 ATOM 6934 O OE1 . GLN A 1 880 ? 32.639 79.163 4.997 1.00 16.96 ? 880 GLN A OE1 1 ATOM 6935 N NE2 . GLN A 1 880 ? 31.715 79.183 2.979 1.00 17.54 ? 880 GLN A NE2 1 ATOM 6936 N N . GLY A 1 881 ? 27.091 79.188 3.185 1.00 15.38 ? 881 GLY A N 1 ATOM 6937 C CA . GLY A 1 881 ? 26.762 78.810 1.828 1.00 15.29 ? 881 GLY A CA 1 ATOM 6938 C C . GLY A 1 881 ? 28.070 78.761 1.006 1.00 13.79 ? 881 GLY A C 1 ATOM 6939 O O . GLY A 1 881 ? 29.166 78.586 1.543 1.00 18.14 ? 881 GLY A O 1 ATOM 6940 N N . VAL A 1 882 ? 27.933 78.886 -0.298 1.00 13.83 ? 882 VAL A N 1 ATOM 6941 C CA . VAL A 1 882 ? 29.110 78.867 -1.162 1.00 12.94 ? 882 VAL A CA 1 ATOM 6942 C C . VAL A 1 882 ? 29.068 80.223 -1.912 1.00 13.34 ? 882 VAL A C 1 ATOM 6943 O O . VAL A 1 882 ? 28.349 80.376 -2.906 1.00 14.98 ? 882 VAL A O 1 ATOM 6944 C CB . VAL A 1 882 ? 29.042 77.667 -2.152 1.00 13.80 ? 882 VAL A CB 1 ATOM 6945 C CG1 . VAL A 1 882 ? 30.230 77.710 -3.135 1.00 14.11 ? 882 VAL A CG1 1 ATOM 6946 C CG2 . VAL A 1 882 ? 29.123 76.366 -1.381 1.00 15.63 ? 882 VAL A CG2 1 ATOM 6947 N N . LEU A 1 883 ? 29.860 81.188 -1.440 1.00 16.95 ? 883 LEU A N 1 ATOM 6948 C CA . LEU A 1 883 ? 29.881 82.530 -2.053 1.00 17.42 ? 883 LEU A CA 1 ATOM 6949 C C . LEU A 1 883 ? 31.315 83.009 -2.229 1.00 17.66 ? 883 LEU A C 1 ATOM 6950 O O . LEU A 1 883 ? 31.588 84.218 -2.146 1.00 18.17 ? 883 LEU A O 1 ATOM 6951 C CB . LEU A 1 883 ? 29.128 83.498 -1.143 1.00 18.69 ? 883 LEU A CB 1 ATOM 6952 C CG . LEU A 1 883 ? 27.644 83.138 -0.900 1.00 18.61 ? 883 LEU A CG 1 ATOM 6953 C CD1 . LEU A 1 883 ? 27.084 84.053 0.106 1.00 20.76 ? 883 LEU A CD1 1 ATOM 6954 C CD2 . LEU A 1 883 ? 26.833 83.268 -2.145 1.00 18.57 ? 883 LEU A CD2 1 ATOM 6955 N N . ASP A 1 884 ? 32.228 82.060 -2.436 1.00 15.72 ? 884 ASP A N 1 ATOM 6956 C CA . ASP A 1 884 ? 33.663 82.307 -2.668 1.00 13.91 ? 884 ASP A CA 1 ATOM 6957 C C . ASP A 1 884 ? 34.162 81.913 -4.036 1.00 12.87 ? 884 ASP A C 1 ATOM 6958 O O . ASP A 1 884 ? 35.372 81.701 -4.254 1.00 12.17 ? 884 ASP A O 1 ATOM 6959 C CB . ASP A 1 884 ? 34.535 81.680 -1.566 1.00 15.31 ? 884 ASP A CB 1 ATOM 6960 C CG . ASP A 1 884 ? 34.277 80.188 -1.369 1.00 15.87 ? 884 ASP A CG 1 ATOM 6961 O OD1 . ASP A 1 884 ? 33.460 79.583 -2.103 1.00 14.19 ? 884 ASP A OD1 1 ATOM 6962 O OD2 . ASP A 1 884 ? 34.918 79.647 -0.446 1.00 15.59 ? 884 ASP A OD2 1 ATOM 6963 N N . ASN A 1 885 ? 33.243 81.815 -4.974 1.00 12.20 ? 885 ASN A N 1 ATOM 6964 C CA . ASN A 1 885 ? 33.545 81.495 -6.376 1.00 13.09 ? 885 ASN A CA 1 ATOM 6965 C C . ASN A 1 885 ? 34.625 82.377 -6.962 1.00 14.19 ? 885 ASN A C 1 ATOM 6966 O O . ASN A 1 885 ? 34.786 83.539 -6.555 1.00 14.44 ? 885 ASN A O 1 ATOM 6967 C CB . ASN A 1 885 ? 32.276 81.658 -7.217 1.00 13.59 ? 885 ASN A CB 1 ATOM 6968 C CG . ASN A 1 885 ? 31.119 81.010 -6.582 1.00 13.28 ? 885 ASN A CG 1 ATOM 6969 O OD1 . ASN A 1 885 ? 30.484 81.579 -5.694 1.00 14.81 ? 885 ASN A OD1 1 ATOM 6970 N ND2 . ASN A 1 885 ? 30.850 79.779 -6.992 1.00 12.68 ? 885 ASN A ND2 1 ATOM 6971 N N . LYS A 1 886 ? 35.404 81.808 -7.863 1.00 13.61 ? 886 LYS A N 1 ATOM 6972 C CA . LYS A 1 886 ? 36.466 82.561 -8.582 1.00 14.27 ? 886 LYS A CA 1 ATOM 6973 C C . LYS A 1 886 ? 36.496 81.988 -9.960 1.00 12.70 ? 886 LYS A C 1 ATOM 6974 O O . LYS A 1 886 ? 36.077 80.816 -10.154 1.00 11.71 ? 886 LYS A O 1 ATOM 6975 C CB . LYS A 1 886 ? 37.852 82.413 -7.945 1.00 17.20 ? 886 LYS A CB 1 ATOM 6976 C CG . LYS A 1 886 ? 38.363 80.982 -7.684 1.00 18.88 ? 886 LYS A CG 1 ATOM 6977 C CD . LYS A 1 886 ? 39.412 80.990 -6.536 1.00 20.09 ? 886 LYS A CD 1 ATOM 6978 C CE . LYS A 1 886 ? 40.725 81.429 -7.062 1.00 17.02 ? 886 LYS A CE 1 ATOM 6979 N NZ . LYS A 1 886 ? 41.816 81.662 -6.051 1.00 19.38 ? 886 LYS A NZ 1 ATOM 6980 N N . PRO A 1 887 ? 37.021 82.748 -10.941 1.00 11.18 ? 887 PRO A N 1 ATOM 6981 C CA . PRO A 1 887 ? 37.107 82.319 -12.326 1.00 12.90 ? 887 PRO A CA 1 ATOM 6982 C C . PRO A 1 887 ? 37.876 81.009 -12.430 1.00 10.98 ? 887 PRO A C 1 ATOM 6983 O O . PRO A 1 887 ? 38.948 80.891 -11.828 1.00 12.57 ? 887 PRO A O 1 ATOM 6984 C CB . PRO A 1 887 ? 37.895 83.475 -12.995 1.00 13.21 ? 887 PRO A CB 1 ATOM 6985 C CG . PRO A 1 887 ? 37.400 84.685 -12.234 1.00 14.89 ? 887 PRO A CG 1 ATOM 6986 C CD . PRO A 1 887 ? 37.381 84.178 -10.793 1.00 14.51 ? 887 PRO A CD 1 ATOM 6987 N N . VAL A 1 888 ? 37.384 80.062 -13.188 1.00 10.34 ? 888 VAL A N 1 ATOM 6988 C CA . VAL A 1 888 ? 38.082 78.805 -13.386 1.00 9.55 ? 888 VAL A CA 1 ATOM 6989 C C . VAL A 1 888 ? 37.984 78.454 -14.848 1.00 11.21 ? 888 VAL A C 1 ATOM 6990 O O . VAL A 1 888 ? 36.937 78.698 -15.460 1.00 12.98 ? 888 VAL A O 1 ATOM 6991 C CB . VAL A 1 888 ? 37.428 77.645 -12.497 1.00 9.77 ? 888 VAL A CB 1 ATOM 6992 C CG1 . VAL A 1 888 ? 35.883 77.536 -12.705 1.00 11.46 ? 888 VAL A CG1 1 ATOM 6993 C CG2 . VAL A 1 888 ? 38.117 76.314 -12.748 1.00 10.25 ? 888 VAL A CG2 1 ATOM 6994 N N . LEU A 1 889 ? 39.045 77.871 -15.426 1.00 8.17 ? 889 LEU A N 1 ATOM 6995 C CA . LEU A 1 889 ? 39.047 77.403 -16.770 1.00 9.77 ? 889 LEU A CA 1 ATOM 6996 C C . LEU A 1 889 ? 38.841 75.870 -16.789 1.00 9.61 ? 889 LEU A C 1 ATOM 6997 O O . LEU A 1 889 ? 39.728 75.051 -16.479 1.00 10.85 ? 889 LEU A O 1 ATOM 6998 C CB . LEU A 1 889 ? 40.399 77.763 -17.471 1.00 9.37 ? 889 LEU A CB 1 ATOM 6999 C CG . LEU A 1 889 ? 40.457 77.334 -18.954 1.00 11.09 ? 889 LEU A CG 1 ATOM 7000 C CD1 . LEU A 1 889 ? 39.584 78.256 -19.775 1.00 12.48 ? 889 LEU A CD1 1 ATOM 7001 C CD2 . LEU A 1 889 ? 41.868 77.298 -19.450 1.00 12.64 ? 889 LEU A CD2 1 ATOM 7002 N N . HIS A 1 890 ? 37.633 75.444 -17.123 1.00 7.26 ? 890 HIS A N 1 ATOM 7003 C CA . HIS A 1 890 ? 37.348 74.022 -17.304 1.00 9.66 ? 890 HIS A CA 1 ATOM 7004 C C . HIS A 1 890 ? 37.730 73.567 -18.695 1.00 9.12 ? 890 HIS A C 1 ATOM 7005 O O . HIS A 1 890 ? 37.464 74.307 -19.667 1.00 9.05 ? 890 HIS A O 1 ATOM 7006 C CB . HIS A 1 890 ? 35.850 73.744 -17.092 1.00 9.24 ? 890 HIS A CB 1 ATOM 7007 C CG . HIS A 1 890 ? 35.404 73.973 -15.678 1.00 9.63 ? 890 HIS A CG 1 ATOM 7008 N ND1 . HIS A 1 890 ? 36.192 73.601 -14.596 1.00 11.74 ? 890 HIS A ND1 1 ATOM 7009 C CD2 . HIS A 1 890 ? 34.245 74.452 -15.156 1.00 10.59 ? 890 HIS A CD2 1 ATOM 7010 C CE1 . HIS A 1 890 ? 35.539 73.832 -13.473 1.00 8.93 ? 890 HIS A CE1 1 ATOM 7011 N NE2 . HIS A 1 890 ? 34.350 74.354 -13.777 1.00 8.54 ? 890 HIS A NE2 1 ATOM 7012 N N . ILE A 1 891 ? 38.294 72.371 -18.855 1.00 8.26 ? 891 ILE A N 1 ATOM 7013 C CA . ILE A 1 891 ? 38.680 71.841 -20.159 1.00 8.84 ? 891 ILE A CA 1 ATOM 7014 C C . ILE A 1 891 ? 38.024 70.498 -20.432 1.00 8.66 ? 891 ILE A C 1 ATOM 7015 O O . ILE A 1 891 ? 37.750 69.733 -19.496 1.00 9.65 ? 891 ILE A O 1 ATOM 7016 C CB . ILE A 1 891 ? 40.237 71.781 -20.298 1.00 9.54 ? 891 ILE A CB 1 ATOM 7017 C CG1 . ILE A 1 891 ? 40.863 70.743 -19.324 1.00 9.61 ? 891 ILE A CG1 1 ATOM 7018 C CG2 . ILE A 1 891 ? 40.774 73.213 -20.006 1.00 10.37 ? 891 ILE A CG2 1 ATOM 7019 C CD1 . ILE A 1 891 ? 42.393 70.559 -19.492 1.00 9.17 ? 891 ILE A CD1 1 ATOM 7020 N N . TYR A 1 892 ? 37.803 70.191 -21.705 1.00 10.18 ? 892 TYR A N 1 ATOM 7021 C CA . TYR A 1 892 ? 37.122 68.986 -22.138 1.00 8.12 ? 892 TYR A CA 1 ATOM 7022 C C . TYR A 1 892 ? 37.546 68.555 -23.530 1.00 9.11 ? 892 TYR A C 1 ATOM 7023 O O . TYR A 1 892 ? 38.170 69.340 -24.269 1.00 9.97 ? 892 TYR A O 1 ATOM 7024 C CB . TYR A 1 892 ? 35.606 69.253 -22.269 1.00 7.70 ? 892 TYR A CB 1 ATOM 7025 C CG . TYR A 1 892 ? 34.948 69.909 -21.091 1.00 6.74 ? 892 TYR A CG 1 ATOM 7026 C CD1 . TYR A 1 892 ? 34.933 71.264 -20.937 1.00 8.83 ? 892 TYR A CD1 1 ATOM 7027 C CD2 . TYR A 1 892 ? 34.368 69.116 -20.072 1.00 10.81 ? 892 TYR A CD2 1 ATOM 7028 C CE1 . TYR A 1 892 ? 34.374 71.870 -19.842 1.00 9.21 ? 892 TYR A CE1 1 ATOM 7029 C CE2 . TYR A 1 892 ? 33.820 69.666 -18.977 1.00 8.15 ? 892 TYR A CE2 1 ATOM 7030 C CZ . TYR A 1 892 ? 33.786 71.058 -18.798 1.00 7.60 ? 892 TYR A CZ 1 ATOM 7031 O OH . TYR A 1 892 ? 33.165 71.662 -17.712 1.00 9.87 ? 892 TYR A OH 1 ATOM 7032 N N . ARG A 1 893 ? 37.208 67.313 -23.886 1.00 8.99 ? 893 ARG A N 1 ATOM 7033 C CA . ARG A 1 893 ? 37.363 66.818 -25.251 1.00 10.85 ? 893 ARG A CA 1 ATOM 7034 C C . ARG A 1 893 ? 35.985 66.245 -25.537 1.00 8.64 ? 893 ARG A C 1 ATOM 7035 O O . ARG A 1 893 ? 35.383 65.556 -24.702 1.00 10.86 ? 893 ARG A O 1 ATOM 7036 C CB . ARG A 1 893 ? 38.426 65.727 -25.454 1.00 9.53 ? 893 ARG A CB 1 ATOM 7037 C CG . ARG A 1 893 ? 39.846 66.270 -25.175 1.00 10.66 ? 893 ARG A CG 1 ATOM 7038 C CD . ARG A 1 893 ? 40.316 67.338 -26.238 1.00 11.29 ? 893 ARG A CD 1 ATOM 7039 N NE . ARG A 1 893 ? 40.390 66.855 -27.625 1.00 11.98 ? 893 ARG A NE 1 ATOM 7040 C CZ . ARG A 1 893 ? 41.366 66.110 -28.111 1.00 11.03 ? 893 ARG A CZ 1 ATOM 7041 N NH1 . ARG A 1 893 ? 42.364 65.720 -27.322 1.00 12.46 ? 893 ARG A NH1 1 ATOM 7042 N NH2 . ARG A 1 893 ? 41.414 65.763 -29.393 1.00 13.49 ? 893 ARG A NH2 1 ATOM 7043 N N . LEU A 1 894 ? 35.487 66.507 -26.751 1.00 11.10 ? 894 LEU A N 1 ATOM 7044 C CA . LEU A 1 894 ? 34.181 66.025 -27.188 1.00 11.58 ? 894 LEU A CA 1 ATOM 7045 C C . LEU A 1 894 ? 34.416 65.072 -28.347 1.00 12.09 ? 894 LEU A C 1 ATOM 7046 O O . LEU A 1 894 ? 34.857 65.496 -29.454 1.00 13.41 ? 894 LEU A O 1 ATOM 7047 C CB . LEU A 1 894 ? 33.348 67.212 -27.620 1.00 12.40 ? 894 LEU A CB 1 ATOM 7048 C CG . LEU A 1 894 ? 31.871 66.838 -27.854 1.00 11.86 ? 894 LEU A CG 1 ATOM 7049 C CD1 . LEU A 1 894 ? 31.139 66.382 -26.540 1.00 12.79 ? 894 LEU A CD1 1 ATOM 7050 C CD2 . LEU A 1 894 ? 31.141 68.053 -28.399 1.00 13.95 ? 894 LEU A CD2 1 ATOM 7051 N N . VAL A 1 895 ? 34.058 63.803 -28.140 1.00 12.77 ? 895 VAL A N 1 ATOM 7052 C CA . VAL A 1 895 ? 34.319 62.777 -29.114 1.00 12.04 ? 895 VAL A CA 1 ATOM 7053 C C . VAL A 1 895 ? 33.033 62.154 -29.652 1.00 13.12 ? 895 VAL A C 1 ATOM 7054 O O . VAL A 1 895 ? 32.338 61.440 -28.937 1.00 12.51 ? 895 VAL A O 1 ATOM 7055 C CB . VAL A 1 895 ? 35.162 61.631 -28.512 1.00 11.52 ? 895 VAL A CB 1 ATOM 7056 C CG1 . VAL A 1 895 ? 35.503 60.595 -29.616 1.00 13.50 ? 895 VAL A CG1 1 ATOM 7057 C CG2 . VAL A 1 895 ? 36.400 62.259 -27.804 1.00 13.73 ? 895 VAL A CG2 1 ATOM 7058 N N . LEU A 1 896 ? 32.733 62.397 -30.926 1.00 14.68 ? 896 LEU A N 1 ATOM 7059 C CA . LEU A 1 896 ? 31.568 61.773 -31.497 1.00 14.55 ? 896 LEU A CA 1 ATOM 7060 C C . LEU A 1 896 ? 32.126 60.679 -32.358 1.00 14.07 ? 896 LEU A C 1 ATOM 7061 O O . LEU A 1 896 ? 33.096 60.885 -33.116 1.00 14.40 ? 896 LEU A O 1 ATOM 7062 C CB . LEU A 1 896 ? 30.766 62.795 -32.347 1.00 14.77 ? 896 LEU A CB 1 ATOM 7063 C CG . LEU A 1 896 ? 29.629 62.221 -33.226 1.00 16.36 ? 896 LEU A CG 1 ATOM 7064 C CD1 . LEU A 1 896 ? 28.390 62.076 -32.439 1.00 17.63 ? 896 LEU A CD1 1 ATOM 7065 C CD2 . LEU A 1 896 ? 29.336 63.212 -34.384 1.00 18.04 ? 896 LEU A CD2 1 ATOM 7066 N N . GLU A 1 897 ? 31.555 59.481 -32.258 1.00 14.01 ? 897 GLU A N 1 ATOM 7067 C CA . GLU A 1 897 ? 32.067 58.383 -33.027 1.00 14.63 ? 897 GLU A CA 1 ATOM 7068 C C . GLU A 1 897 ? 30.992 57.344 -33.361 1.00 15.26 ? 897 GLU A C 1 ATOM 7069 O O . GLU A 1 897 ? 29.984 57.257 -32.679 1.00 15.13 ? 897 GLU A O 1 ATOM 7070 C CB . GLU A 1 897 ? 33.267 57.758 -32.263 1.00 18.37 ? 897 GLU A CB 1 ATOM 7071 C CG . GLU A 1 897 ? 32.942 57.184 -30.925 1.00 20.52 ? 897 GLU A CG 1 ATOM 7072 C CD . GLU A 1 897 ? 34.197 57.163 -29.955 1.00 20.74 ? 897 GLU A CD 1 ATOM 7073 O OE1 . GLU A 1 897 ? 35.369 57.115 -30.393 1.00 20.19 ? 897 GLU A OE1 1 ATOM 7074 O OE2 . GLU A 1 897 ? 33.946 57.207 -28.754 1.00 23.73 ? 897 GLU A OE2 1 ATOM 7075 N N . LYS A 1 898 ? 31.208 56.592 -34.437 1.00 18.60 ? 898 LYS A N 1 ATOM 7076 C CA . LYS A 1 898 ? 30.310 55.519 -34.831 1.00 19.22 ? 898 LYS A CA 1 ATOM 7077 C C . LYS A 1 898 ? 30.751 54.292 -34.056 1.00 20.28 ? 898 LYS A C 1 ATOM 7078 O O . LYS A 1 898 ? 31.951 53.995 -34.028 1.00 20.14 ? 898 LYS A O 1 ATOM 7079 C CB . LYS A 1 898 ? 30.430 55.270 -36.344 1.00 22.37 ? 898 LYS A CB 1 ATOM 7080 C CG . LYS A 1 898 ? 29.942 56.435 -37.144 1.00 23.82 ? 898 LYS A CG 1 ATOM 7081 C CD . LYS A 1 898 ? 28.819 57.185 -36.378 1.00 26.99 ? 898 LYS A CD 1 ATOM 7082 C CE . LYS A 1 898 ? 27.401 56.840 -36.877 1.00 28.76 ? 898 LYS A CE 1 ATOM 7083 N NZ . LYS A 1 898 ? 27.144 55.362 -37.004 1.00 31.38 ? 898 LYS A NZ 1 ATOM 7084 N N . VAL A 1 899 ? 29.808 53.580 -33.441 1.00 19.04 ? 899 VAL A N 1 ATOM 7085 C CA . VAL A 1 899 ? 30.153 52.412 -32.642 1.00 19.57 ? 899 VAL A CA 1 ATOM 7086 C C . VAL A 1 899 ? 29.368 51.132 -33.045 1.00 19.28 ? 899 VAL A C 1 ATOM 7087 O O . VAL A 1 899 ? 29.319 50.125 -32.318 1.00 17.28 ? 899 VAL A O 1 ATOM 7088 C CB . VAL A 1 899 ? 29.941 52.755 -31.142 1.00 19.01 ? 899 VAL A CB 1 ATOM 7089 C CG1 . VAL A 1 899 ? 30.869 53.893 -30.742 1.00 19.85 ? 899 VAL A CG1 1 ATOM 7090 C CG2 . VAL A 1 899 ? 28.516 53.152 -30.928 1.00 19.92 ? 899 VAL A CG2 1 ATOM 7091 N N . ASN A 1 900 ? 28.782 51.150 -34.242 1.00 19.15 ? 900 ASN A N 1 ATOM 7092 C CA . ASN A 1 900 ? 28.042 49.982 -34.698 1.00 19.36 ? 900 ASN A CA 1 ATOM 7093 C C . ASN A 1 900 ? 28.991 48.829 -34.941 1.00 18.24 ? 900 ASN A C 1 ATOM 7094 O O . ASN A 1 900 ? 28.576 47.689 -34.865 1.00 21.05 ? 900 ASN A O 1 ATOM 7095 C CB . ASN A 1 900 ? 27.246 50.306 -35.982 1.00 19.98 ? 900 ASN A CB 1 ATOM 7096 C CG . ASN A 1 900 ? 28.120 50.866 -37.081 1.00 21.76 ? 900 ASN A CG 1 ATOM 7097 O OD1 . ASN A 1 900 ? 28.712 51.954 -36.956 1.00 23.49 ? 900 ASN A OD1 1 ATOM 7098 N ND2 . ASN A 1 900 ? 28.217 50.119 -38.185 1.00 24.37 ? 900 ASN A ND2 1 ATOM 7099 N N . ASN A 1 901 ? 30.269 49.097 -35.174 1.00 18.72 ? 901 ASN A N 1 ATOM 7100 C CA . ASN A 1 901 ? 31.207 48.000 -35.378 1.00 19.49 ? 901 ASN A CA 1 ATOM 7101 C C . ASN A 1 901 ? 31.991 47.575 -34.162 1.00 18.34 ? 901 ASN A C 1 ATOM 7102 O O . ASN A 1 901 ? 32.762 46.587 -34.226 1.00 19.04 ? 901 ASN A O 1 ATOM 7103 C CB . ASN A 1 901 ? 32.182 48.333 -36.490 1.00 22.02 ? 901 ASN A CB 1 ATOM 7104 C CG . ASN A 1 901 ? 31.515 48.353 -37.847 1.00 24.57 ? 901 ASN A CG 1 ATOM 7105 O OD1 . ASN A 1 901 ? 31.735 49.287 -38.607 1.00 28.59 ? 901 ASN A OD1 1 ATOM 7106 N ND2 . ASN A 1 901 ? 30.712 47.329 -38.162 1.00 26.26 ? 901 ASN A ND2 1 ATOM 7107 N N . CYS A 1 902 ? 31.810 48.285 -33.051 1.00 17.78 ? 902 CYS A N 1 ATOM 7108 C CA . CYS A 1 902 ? 32.540 47.899 -31.830 1.00 17.42 ? 902 CYS A CA 1 ATOM 7109 C C . CYS A 1 902 ? 31.962 46.696 -31.080 1.00 15.94 ? 902 CYS A C 1 ATOM 7110 O O . CYS A 1 902 ? 30.737 46.539 -30.986 1.00 17.30 ? 902 CYS A O 1 ATOM 7111 C CB . CYS A 1 902 ? 32.547 49.038 -30.838 1.00 16.71 ? 902 CYS A CB 1 ATOM 7112 S SG . CYS A 1 902 ? 33.208 50.626 -31.432 1.00 19.12 ? 902 CYS A SG 1 ATOM 7113 N N . VAL A 1 903 ? 32.851 45.882 -30.522 1.00 16.05 ? 903 VAL A N 1 ATOM 7114 C CA . VAL A 1 903 ? 32.449 44.743 -29.700 1.00 17.34 ? 903 VAL A CA 1 ATOM 7115 C C . VAL A 1 903 ? 32.183 45.305 -28.296 1.00 17.23 ? 903 VAL A C 1 ATOM 7116 O O . VAL A 1 903 ? 33.110 45.650 -27.545 1.00 17.96 ? 903 VAL A O 1 ATOM 7117 C CB . VAL A 1 903 ? 33.569 43.699 -29.695 1.00 15.74 ? 903 VAL A CB 1 ATOM 7118 C CG1 . VAL A 1 903 ? 33.219 42.591 -28.729 1.00 17.04 ? 903 VAL A CG1 1 ATOM 7119 C CG2 . VAL A 1 903 ? 33.792 43.200 -31.165 1.00 14.67 ? 903 VAL A CG2 1 ATOM 7120 N N . ARG A 1 904 ? 30.905 45.443 -27.976 1.00 17.40 ? 904 ARG A N 1 ATOM 7121 C CA . ARG A 1 904 ? 30.488 46.026 -26.709 1.00 16.34 ? 904 ARG A CA 1 ATOM 7122 C C . ARG A 1 904 ? 29.935 44.967 -25.775 1.00 15.76 ? 904 ARG A C 1 ATOM 7123 O O . ARG A 1 904 ? 29.553 43.857 -26.192 1.00 14.07 ? 904 ARG A O 1 ATOM 7124 C CB . ARG A 1 904 ? 29.421 47.104 -26.980 1.00 17.54 ? 904 ARG A CB 1 ATOM 7125 C CG . ARG A 1 904 ? 30.037 48.396 -27.544 1.00 18.14 ? 904 ARG A CG 1 ATOM 7126 C CD . ARG A 1 904 ? 29.029 49.474 -27.859 1.00 20.95 ? 904 ARG A CD 1 ATOM 7127 N NE . ARG A 1 904 ? 28.231 49.074 -29.020 1.00 21.90 ? 904 ARG A NE 1 ATOM 7128 C CZ . ARG A 1 904 ? 27.218 49.773 -29.534 1.00 21.30 ? 904 ARG A CZ 1 ATOM 7129 N NH1 . ARG A 1 904 ? 26.838 50.914 -29.021 1.00 22.63 ? 904 ARG A NH1 1 ATOM 7130 N NH2 . ARG A 1 904 ? 26.569 49.297 -30.586 1.00 21.14 ? 904 ARG A NH2 1 ATOM 7131 N N . PRO A 1 905 ? 29.892 45.289 -24.472 1.00 13.37 ? 905 PRO A N 1 ATOM 7132 C CA . PRO A 1 905 ? 29.355 44.332 -23.493 1.00 14.36 ? 905 PRO A CA 1 ATOM 7133 C C . PRO A 1 905 ? 27.874 44.117 -23.796 1.00 14.20 ? 905 PRO A C 1 ATOM 7134 O O . PRO A 1 905 ? 27.267 44.986 -24.415 1.00 14.91 ? 905 PRO A O 1 ATOM 7135 C CB . PRO A 1 905 ? 29.531 45.083 -22.163 1.00 13.86 ? 905 PRO A CB 1 ATOM 7136 C CG . PRO A 1 905 ? 30.593 46.100 -22.419 1.00 13.16 ? 905 PRO A CG 1 ATOM 7137 C CD . PRO A 1 905 ? 30.340 46.544 -23.829 1.00 14.67 ? 905 PRO A CD 1 ATOM 7138 N N . SER A 1 906 ? 27.272 43.022 -23.311 1.00 13.92 ? 906 SER A N 1 ATOM 7139 C CA . SER A 1 906 ? 25.859 42.761 -23.529 1.00 17.51 ? 906 SER A CA 1 ATOM 7140 C C . SER A 1 906 ? 24.989 43.715 -22.720 1.00 17.97 ? 906 SER A C 1 ATOM 7141 O O . SER A 1 906 ? 25.485 44.467 -21.894 1.00 17.17 ? 906 SER A O 1 ATOM 7142 C CB . SER A 1 906 ? 25.528 41.305 -23.179 1.00 18.93 ? 906 SER A CB 1 ATOM 7143 O OG . SER A 1 906 ? 25.466 41.155 -21.790 1.00 23.96 ? 906 SER A OG 1 ATOM 7144 N N . LYS A 1 907 ? 23.683 43.699 -22.982 1.00 18.82 ? 907 LYS A N 1 ATOM 7145 C CA . LYS A 1 907 ? 22.731 44.585 -22.311 1.00 21.42 ? 907 LYS A CA 1 ATOM 7146 C C . LYS A 1 907 ? 22.715 44.457 -20.797 1.00 20.03 ? 907 LYS A C 1 ATOM 7147 O O . LYS A 1 907 ? 22.353 45.389 -20.092 1.00 20.91 ? 907 LYS A O 1 ATOM 7148 C CB . LYS A 1 907 ? 21.321 44.334 -22.877 1.00 24.32 ? 907 LYS A CB 1 ATOM 7149 C CG . LYS A 1 907 ? 21.211 44.765 -24.316 1.00 29.07 ? 907 LYS A CG 1 ATOM 7150 C CD . LYS A 1 907 ? 19.867 44.361 -24.941 1.00 31.56 ? 907 LYS A CD 1 ATOM 7151 C CE . LYS A 1 907 ? 19.734 45.012 -26.333 1.00 32.82 ? 907 LYS A CE 1 ATOM 7152 N NZ . LYS A 1 907 ? 19.873 46.529 -26.250 1.00 35.21 ? 907 LYS A NZ 1 ATOM 7153 N N . LEU A 1 908 ? 23.119 43.300 -20.307 1.00 19.36 ? 908 LEU A N 1 ATOM 7154 C CA . LEU A 1 908 ? 23.120 43.074 -18.852 1.00 18.70 ? 908 LEU A CA 1 ATOM 7155 C C . LEU A 1 908 ? 24.418 43.410 -18.106 1.00 17.23 ? 908 LEU A C 1 ATOM 7156 O O . LEU A 1 908 ? 24.477 43.385 -16.869 1.00 17.60 ? 908 LEU A O 1 ATOM 7157 C CB . LEU A 1 908 ? 22.738 41.619 -18.574 1.00 21.89 ? 908 LEU A CB 1 ATOM 7158 C CG . LEU A 1 908 ? 21.336 41.310 -19.105 1.00 23.76 ? 908 LEU A CG 1 ATOM 7159 C CD1 . LEU A 1 908 ? 20.951 39.925 -18.581 1.00 25.69 ? 908 LEU A CD1 1 ATOM 7160 C CD2 . LEU A 1 908 ? 20.325 42.360 -18.656 1.00 25.20 ? 908 LEU A CD2 1 ATOM 7161 N N . HIS A 1 909 ? 25.468 43.698 -18.857 1.00 16.30 ? 909 HIS A N 1 ATOM 7162 C CA . HIS A 1 909 ? 26.756 44.013 -18.272 1.00 13.42 ? 909 HIS A CA 1 ATOM 7163 C C . HIS A 1 909 ? 26.712 45.413 -17.627 1.00 12.50 ? 909 HIS A C 1 ATOM 7164 O O . HIS A 1 909 ? 26.257 46.369 -18.230 1.00 13.09 ? 909 HIS A O 1 ATOM 7165 C CB . HIS A 1 909 ? 27.830 43.923 -19.344 1.00 13.04 ? 909 HIS A CB 1 ATOM 7166 C CG . HIS A 1 909 ? 29.195 43.749 -18.800 1.00 12.84 ? 909 HIS A CG 1 ATOM 7167 N ND1 . HIS A 1 909 ? 29.843 44.711 -18.048 1.00 13.01 ? 909 HIS A ND1 1 ATOM 7168 C CD2 . HIS A 1 909 ? 30.053 42.717 -18.924 1.00 12.17 ? 909 HIS A CD2 1 ATOM 7169 C CE1 . HIS A 1 909 ? 31.047 44.267 -17.733 1.00 12.88 ? 909 HIS A CE1 1 ATOM 7170 N NE2 . HIS A 1 909 ? 31.202 43.061 -18.255 1.00 13.43 ? 909 HIS A NE2 1 ATOM 7171 N N . PRO A 1 910 ? 27.183 45.521 -16.361 1.00 11.19 ? 910 PRO A N 1 ATOM 7172 C CA . PRO A 1 910 ? 27.167 46.809 -15.657 1.00 10.77 ? 910 PRO A CA 1 ATOM 7173 C C . PRO A 1 910 ? 28.257 47.819 -16.016 1.00 10.30 ? 910 PRO A C 1 ATOM 7174 O O . PRO A 1 910 ? 28.189 48.924 -15.527 1.00 10.11 ? 910 PRO A O 1 ATOM 7175 C CB . PRO A 1 910 ? 27.196 46.401 -14.195 1.00 13.66 ? 910 PRO A CB 1 ATOM 7176 C CG . PRO A 1 910 ? 27.949 45.105 -14.187 1.00 14.34 ? 910 PRO A CG 1 ATOM 7177 C CD . PRO A 1 910 ? 27.618 44.404 -15.520 1.00 13.21 ? 910 PRO A CD 1 ATOM 7178 N N . ALA A 1 911 ? 29.214 47.428 -16.869 1.00 11.27 ? 911 ALA A N 1 ATOM 7179 C CA . ALA A 1 911 ? 30.308 48.362 -17.256 1.00 9.30 ? 911 ALA A CA 1 ATOM 7180 C C . ALA A 1 911 ? 30.209 48.845 -18.694 1.00 9.72 ? 911 ALA A C 1 ATOM 7181 O O . ALA A 1 911 ? 29.455 48.297 -19.523 1.00 10.81 ? 911 ALA A O 1 ATOM 7182 C CB . ALA A 1 911 ? 31.687 47.653 -17.059 1.00 8.79 ? 911 ALA A CB 1 ATOM 7183 N N . GLY A 1 912 ? 31.015 49.873 -18.969 1.00 9.88 ? 912 GLY A N 1 ATOM 7184 C CA . GLY A 1 912 ? 31.173 50.421 -20.303 1.00 9.02 ? 912 GLY A CA 1 ATOM 7185 C C . GLY A 1 912 ? 32.671 50.657 -20.510 1.00 10.23 ? 912 GLY A C 1 ATOM 7186 O O . GLY A 1 912 ? 33.407 50.704 -19.527 1.00 10.99 ? 912 GLY A O 1 ATOM 7187 N N . TYR A 1 913 ? 33.145 50.822 -21.756 1.00 10.51 ? 913 TYR A N 1 ATOM 7188 C CA . TYR A 1 913 ? 34.561 51.036 -22.013 1.00 10.63 ? 913 TYR A CA 1 ATOM 7189 C C . TYR A 1 913 ? 34.725 52.068 -23.105 1.00 10.89 ? 913 TYR A C 1 ATOM 7190 O O . TYR A 1 913 ? 33.922 52.136 -24.106 1.00 10.15 ? 913 TYR A O 1 ATOM 7191 C CB . TYR A 1 913 ? 35.260 49.749 -22.475 1.00 10.72 ? 913 TYR A CB 1 ATOM 7192 C CG . TYR A 1 913 ? 35.192 48.686 -21.447 1.00 10.47 ? 913 TYR A CG 1 ATOM 7193 C CD1 . TYR A 1 913 ? 36.038 48.711 -20.370 1.00 9.69 ? 913 TYR A CD1 1 ATOM 7194 C CD2 . TYR A 1 913 ? 34.208 47.717 -21.502 1.00 10.63 ? 913 TYR A CD2 1 ATOM 7195 C CE1 . TYR A 1 913 ? 35.931 47.849 -19.347 1.00 9.72 ? 913 TYR A CE1 1 ATOM 7196 C CE2 . TYR A 1 913 ? 34.059 46.779 -20.430 1.00 9.38 ? 913 TYR A CE2 1 ATOM 7197 C CZ . TYR A 1 913 ? 34.948 46.872 -19.353 1.00 10.13 ? 913 TYR A CZ 1 ATOM 7198 O OH . TYR A 1 913 ? 34.836 45.993 -18.285 1.00 12.78 ? 913 TYR A OH 1 ATOM 7199 N N . LEU A 1 914 ? 35.794 52.817 -22.969 1.00 11.71 ? 914 LEU A N 1 ATOM 7200 C CA . LEU A 1 914 ? 36.155 53.843 -23.965 1.00 11.53 ? 914 LEU A CA 1 ATOM 7201 C C . LEU A 1 914 ? 36.791 53.228 -25.239 1.00 12.29 ? 914 LEU A C 1 ATOM 7202 O O . LEU A 1 914 ? 37.235 52.082 -25.252 1.00 10.88 ? 914 LEU A O 1 ATOM 7203 C CB . LEU A 1 914 ? 37.173 54.818 -23.357 1.00 10.26 ? 914 LEU A CB 1 ATOM 7204 C CG . LEU A 1 914 ? 36.772 55.705 -22.199 1.00 8.72 ? 914 LEU A CG 1 ATOM 7205 C CD1 . LEU A 1 914 ? 37.864 56.758 -21.982 1.00 9.58 ? 914 LEU A CD1 1 ATOM 7206 C CD2 . LEU A 1 914 ? 35.482 56.449 -22.559 1.00 10.79 ? 914 LEU A CD2 1 ATOM 7207 N N . THR A 1 915 ? 36.771 54.027 -26.318 1.00 13.06 ? 915 THR A N 1 ATOM 7208 C CA . THR A 1 915 ? 37.414 53.665 -27.550 1.00 11.99 ? 915 THR A CA 1 ATOM 7209 C C . THR A 1 915 ? 38.814 54.259 -27.427 1.00 13.52 ? 915 THR A C 1 ATOM 7210 O O . THR A 1 915 ? 39.104 55.070 -26.498 1.00 12.15 ? 915 THR A O 1 ATOM 7211 C CB . THR A 1 915 ? 36.729 54.364 -28.742 1.00 13.02 ? 915 THR A CB 1 ATOM 7212 O OG1 . THR A 1 915 ? 36.739 55.772 -28.516 1.00 15.30 ? 915 THR A OG1 1 ATOM 7213 C CG2 . THR A 1 915 ? 35.303 53.875 -28.939 1.00 13.17 ? 915 THR A CG2 1 ATOM 7214 N N . SER A 1 916 ? 39.681 53.876 -28.366 1.00 13.55 ? 916 SER A N 1 ATOM 7215 C CA . SER A 1 916 ? 41.038 54.404 -28.409 1.00 13.28 ? 916 SER A CA 1 ATOM 7216 C C . SER A 1 916 ? 41.032 55.934 -28.471 1.00 12.16 ? 916 SER A C 1 ATOM 7217 O O . SER A 1 916 ? 41.753 56.605 -27.743 1.00 12.78 ? 916 SER A O 1 ATOM 7218 C CB . SER A 1 916 ? 41.766 53.845 -29.648 1.00 14.19 ? 916 SER A CB 1 ATOM 7219 O OG . SER A 1 916 ? 43.018 54.506 -29.778 1.00 19.10 ? 916 SER A OG 1 ATOM 7220 N N . ALA A 1 917 ? 40.189 56.486 -29.343 1.00 10.01 ? 917 ALA A N 1 ATOM 7221 C CA . ALA A 1 917 ? 40.199 57.936 -29.481 1.00 10.50 ? 917 ALA A CA 1 ATOM 7222 C C . ALA A 1 917 ? 39.767 58.671 -28.185 1.00 9.89 ? 917 ALA A C 1 ATOM 7223 O O . ALA A 1 917 ? 40.318 59.692 -27.795 1.00 10.20 ? 917 ALA A O 1 ATOM 7224 C CB . ALA A 1 917 ? 39.298 58.341 -30.653 1.00 12.11 ? 917 ALA A CB 1 ATOM 7225 N N . ALA A 1 918 ? 38.777 58.112 -27.504 1.00 11.24 ? 918 ALA A N 1 ATOM 7226 C CA . ALA A 1 918 ? 38.303 58.734 -26.296 1.00 9.79 ? 918 ALA A CA 1 ATOM 7227 C C . ALA A 1 918 ? 39.289 58.632 -25.134 1.00 10.41 ? 918 ALA A C 1 ATOM 7228 O O . ALA A 1 918 ? 39.478 59.591 -24.408 1.00 11.29 ? 918 ALA A O 1 ATOM 7229 C CB . ALA A 1 918 ? 36.920 58.163 -25.934 1.00 9.99 ? 918 ALA A CB 1 ATOM 7230 N N . HIS A 1 919 ? 39.972 57.495 -25.041 1.00 9.06 ? 919 HIS A N 1 ATOM 7231 C CA . HIS A 1 919 ? 40.982 57.324 -23.990 1.00 11.02 ? 919 HIS A CA 1 ATOM 7232 C C . HIS A 1 919 ? 42.167 58.286 -24.289 1.00 9.72 ? 919 HIS A C 1 ATOM 7233 O O . HIS A 1 919 ? 42.654 58.944 -23.395 1.00 10.29 ? 919 HIS A O 1 ATOM 7234 C CB . HIS A 1 919 ? 41.438 55.878 -24.033 1.00 9.84 ? 919 HIS A CB 1 ATOM 7235 C CG . HIS A 1 919 ? 42.562 55.583 -23.114 1.00 13.34 ? 919 HIS A CG 1 ATOM 7236 N ND1 . HIS A 1 919 ? 43.805 55.213 -23.586 1.00 13.89 ? 919 HIS A ND1 1 ATOM 7237 C CD2 . HIS A 1 919 ? 42.669 55.693 -21.773 1.00 12.32 ? 919 HIS A CD2 1 ATOM 7238 C CE1 . HIS A 1 919 ? 44.637 55.108 -22.561 1.00 14.33 ? 919 HIS A CE1 1 ATOM 7239 N NE2 . HIS A 1 919 ? 43.980 55.391 -21.458 1.00 14.37 ? 919 HIS A NE2 1 ATOM 7240 N N . LYS A 1 920 ? 42.606 58.386 -25.539 1.00 11.35 ? 920 LYS A N 1 ATOM 7241 C CA . LYS A 1 920 ? 43.715 59.298 -25.770 1.00 10.51 ? 920 LYS A CA 1 ATOM 7242 C C . LYS A 1 920 ? 43.265 60.720 -25.490 1.00 9.33 ? 920 LYS A C 1 ATOM 7243 O O . LYS A 1 920 ? 44.057 61.551 -25.052 1.00 10.90 ? 920 LYS A O 1 ATOM 7244 C CB . LYS A 1 920 ? 44.236 59.213 -27.192 1.00 12.98 ? 920 LYS A CB 1 ATOM 7245 C CG . LYS A 1 920 ? 45.162 57.970 -27.346 1.00 15.11 ? 920 LYS A CG 1 ATOM 7246 C CD . LYS A 1 920 ? 45.792 57.808 -28.741 1.00 17.79 ? 920 LYS A CD 1 ATOM 7247 C CE . LYS A 1 920 ? 46.870 56.733 -28.755 1.00 18.45 ? 920 LYS A CE 1 ATOM 7248 N NZ . LYS A 1 920 ? 48.010 56.941 -27.853 1.00 15.20 ? 920 LYS A NZ 1 ATOM 7249 N N . ALA A 1 921 ? 42.016 61.036 -25.804 1.00 8.47 ? 921 ALA A N 1 ATOM 7250 C CA . ALA A 1 921 ? 41.509 62.356 -25.558 1.00 9.46 ? 921 ALA A CA 1 ATOM 7251 C C . ALA A 1 921 ? 41.551 62.634 -24.032 1.00 10.58 ? 921 ALA A C 1 ATOM 7252 O O . ALA A 1 921 ? 41.873 63.725 -23.600 1.00 9.88 ? 921 ALA A O 1 ATOM 7253 C CB . ALA A 1 921 ? 40.061 62.473 -26.141 1.00 8.76 ? 921 ALA A CB 1 ATOM 7254 N N . SER A 1 922 ? 41.137 61.632 -23.236 1.00 9.26 ? 922 SER A N 1 ATOM 7255 C CA . SER A 1 922 ? 41.258 61.826 -21.769 1.00 7.10 ? 922 SER A CA 1 ATOM 7256 C C . SER A 1 922 ? 42.737 62.066 -21.287 1.00 9.89 ? 922 SER A C 1 ATOM 7257 O O . SER A 1 922 ? 42.997 62.969 -20.459 1.00 8.53 ? 922 SER A O 1 ATOM 7258 C CB . SER A 1 922 ? 40.662 60.600 -21.041 1.00 8.87 ? 922 SER A CB 1 ATOM 7259 O OG . SER A 1 922 ? 40.844 60.756 -19.643 1.00 7.33 ? 922 SER A OG 1 ATOM 7260 N N . GLN A 1 923 ? 43.682 61.325 -21.875 1.00 8.42 ? 923 GLN A N 1 ATOM 7261 C CA . GLN A 1 923 ? 45.102 61.478 -21.507 1.00 10.04 ? 923 GLN A CA 1 ATOM 7262 C C . GLN A 1 923 ? 45.592 62.873 -21.896 1.00 9.86 ? 923 GLN A C 1 ATOM 7263 O O . GLN A 1 923 ? 46.387 63.499 -21.162 1.00 11.05 ? 923 GLN A O 1 ATOM 7264 C CB . GLN A 1 923 ? 45.950 60.395 -22.183 1.00 9.68 ? 923 GLN A CB 1 ATOM 7265 C CG . GLN A 1 923 ? 45.634 58.938 -21.708 1.00 9.72 ? 923 GLN A CG 1 ATOM 7266 C CD . GLN A 1 923 ? 46.590 57.950 -22.317 1.00 9.63 ? 923 GLN A CD 1 ATOM 7267 O OE1 . GLN A 1 923 ? 46.758 57.979 -23.533 1.00 13.39 ? 923 GLN A OE1 1 ATOM 7268 N NE2 . GLN A 1 923 ? 47.220 57.074 -21.501 1.00 10.14 ? 923 GLN A NE2 1 ATOM 7269 N N . SER A 1 924 ? 45.061 63.423 -23.015 1.00 9.58 ? 924 SER A N 1 ATOM 7270 C CA . SER A 1 924 ? 45.496 64.765 -23.433 1.00 8.47 ? 924 SER A CA 1 ATOM 7271 C C . SER A 1 924 ? 45.129 65.862 -22.458 1.00 9.12 ? 924 SER A C 1 ATOM 7272 O O . SER A 1 924 ? 45.782 66.885 -22.468 1.00 10.54 ? 924 SER A O 1 ATOM 7273 C CB . SER A 1 924 ? 44.888 65.129 -24.818 1.00 11.52 ? 924 SER A CB 1 ATOM 7274 O OG . SER A 1 924 ? 43.525 65.539 -24.703 1.00 12.74 ? 924 SER A OG 1 ATOM 7275 N N . LEU A 1 925 ? 44.085 65.660 -21.641 1.00 10.18 ? 925 LEU A N 1 ATOM 7276 C CA . LEU A 1 925 ? 43.596 66.627 -20.679 1.00 9.39 ? 925 LEU A CA 1 ATOM 7277 C C . LEU A 1 925 ? 44.284 66.395 -19.336 1.00 10.12 ? 925 LEU A C 1 ATOM 7278 O O . LEU A 1 925 ? 44.685 67.315 -18.677 1.00 10.77 ? 925 LEU A O 1 ATOM 7279 C CB . LEU A 1 925 ? 42.072 66.480 -20.462 1.00 10.65 ? 925 LEU A CB 1 ATOM 7280 C CG . LEU A 1 925 ? 41.190 66.636 -21.689 1.00 10.66 ? 925 LEU A CG 1 ATOM 7281 C CD1 . LEU A 1 925 ? 39.803 66.325 -21.276 1.00 10.85 ? 925 LEU A CD1 1 ATOM 7282 C CD2 . LEU A 1 925 ? 41.288 68.126 -22.222 1.00 8.90 ? 925 LEU A CD2 1 ATOM 7283 N N . LEU A 1 926 ? 44.419 65.117 -18.987 1.00 9.88 ? 926 LEU A N 1 ATOM 7284 C CA . LEU A 1 926 ? 45.042 64.849 -17.705 1.00 8.18 ? 926 LEU A CA 1 ATOM 7285 C C . LEU A 1 926 ? 46.559 64.810 -17.655 1.00 8.59 ? 926 LEU A C 1 ATOM 7286 O O . LEU A 1 926 ? 47.107 65.224 -16.650 1.00 10.65 ? 926 LEU A O 1 ATOM 7287 C CB . LEU A 1 926 ? 44.447 63.544 -17.124 1.00 9.64 ? 926 LEU A CB 1 ATOM 7288 C CG . LEU A 1 926 ? 42.922 63.626 -16.811 1.00 10.20 ? 926 LEU A CG 1 ATOM 7289 C CD1 . LEU A 1 926 ? 42.500 62.223 -16.301 1.00 11.42 ? 926 LEU A CD1 1 ATOM 7290 C CD2 . LEU A 1 926 ? 42.564 64.699 -15.773 1.00 11.60 ? 926 LEU A CD2 1 ATOM 7291 N N . ASP A 1 927 ? 47.222 64.326 -18.709 1.00 10.09 ? 927 ASP A N 1 ATOM 7292 C CA . ASP A 1 927 ? 48.681 64.242 -18.748 1.00 9.88 ? 927 ASP A CA 1 ATOM 7293 C C . ASP A 1 927 ? 49.263 64.770 -20.060 1.00 9.64 ? 927 ASP A C 1 ATOM 7294 O O . ASP A 1 927 ? 49.808 64.059 -20.837 1.00 9.11 ? 927 ASP A O 1 ATOM 7295 C CB . ASP A 1 927 ? 49.097 62.807 -18.480 1.00 11.25 ? 927 ASP A CB 1 ATOM 7296 C CG . ASP A 1 927 ? 48.748 62.378 -17.032 1.00 9.94 ? 927 ASP A CG 1 ATOM 7297 O OD1 . ASP A 1 927 ? 49.481 62.758 -16.069 1.00 8.80 ? 927 ASP A OD1 1 ATOM 7298 O OD2 . ASP A 1 927 ? 47.722 61.639 -16.872 1.00 10.52 ? 927 ASP A OD2 1 ATOM 7299 N N . PRO A 1 928 ? 49.089 66.078 -20.280 1.00 11.92 ? 928 PRO A N 1 ATOM 7300 C CA . PRO A 1 928 ? 49.599 66.709 -21.502 1.00 10.80 ? 928 PRO A CA 1 ATOM 7301 C C . PRO A 1 928 ? 51.092 66.730 -21.472 1.00 12.63 ? 928 PRO A C 1 ATOM 7302 O O . PRO A 1 928 ? 51.721 66.434 -20.453 1.00 11.57 ? 928 PRO A O 1 ATOM 7303 C CB . PRO A 1 928 ? 49.057 68.154 -21.428 1.00 10.75 ? 928 PRO A CB 1 ATOM 7304 C CG . PRO A 1 928 ? 48.971 68.440 -19.938 1.00 11.47 ? 928 PRO A CG 1 ATOM 7305 C CD . PRO A 1 928 ? 48.513 67.064 -19.350 1.00 11.51 ? 928 PRO A CD 1 ATOM 7306 N N . LEU A 1 929 ? 51.678 67.158 -22.582 1.00 10.64 ? 929 LEU A N 1 ATOM 7307 C CA . LEU A 1 929 ? 53.128 67.319 -22.545 1.00 9.90 ? 929 LEU A CA 1 ATOM 7308 C C . LEU A 1 929 ? 53.443 68.493 -21.632 1.00 9.61 ? 929 LEU A C 1 ATOM 7309 O O . LEU A 1 929 ? 52.678 69.438 -21.482 1.00 11.69 ? 929 LEU A O 1 ATOM 7310 C CB . LEU A 1 929 ? 53.648 67.721 -23.933 1.00 10.42 ? 929 LEU A CB 1 ATOM 7311 C CG . LEU A 1 929 ? 53.500 66.697 -25.045 1.00 9.68 ? 929 LEU A CG 1 ATOM 7312 C CD1 . LEU A 1 929 ? 54.144 67.365 -26.307 1.00 10.19 ? 929 LEU A CD1 1 ATOM 7313 C CD2 . LEU A 1 929 ? 54.207 65.346 -24.805 1.00 9.50 ? 929 LEU A CD2 1 ATOM 7314 N N . ASP A 1 930 ? 54.563 68.415 -20.912 1.00 9.56 ? 930 ASP A N 1 ATOM 7315 C CA . ASP A 1 930 ? 55.010 69.526 -20.084 1.00 8.49 ? 930 ASP A CA 1 ATOM 7316 C C . ASP A 1 930 ? 55.969 70.398 -20.928 1.00 9.29 ? 930 ASP A C 1 ATOM 7317 O O . ASP A 1 930 ? 56.699 69.839 -21.780 1.00 11.56 ? 930 ASP A O 1 ATOM 7318 C CB . ASP A 1 930 ? 55.773 68.975 -18.851 1.00 9.38 ? 930 ASP A CB 1 ATOM 7319 C CG . ASP A 1 930 ? 54.951 67.926 -18.137 1.00 10.81 ? 930 ASP A CG 1 ATOM 7320 O OD1 . ASP A 1 930 ? 53.866 68.369 -17.649 1.00 13.20 ? 930 ASP A OD1 1 ATOM 7321 O OD2 . ASP A 1 930 ? 55.354 66.716 -18.108 1.00 11.51 ? 930 ASP A OD2 1 ATOM 7322 N N . LYS A 1 931 ? 55.948 71.696 -20.690 1.00 10.63 ? 931 LYS A N 1 ATOM 7323 C CA . LYS A 1 931 ? 56.718 72.644 -21.468 1.00 10.17 ? 931 LYS A CA 1 ATOM 7324 C C . LYS A 1 931 ? 57.641 73.449 -20.610 1.00 10.69 ? 931 LYS A C 1 ATOM 7325 O O . LYS A 1 931 ? 57.247 74.100 -19.625 1.00 11.70 ? 931 LYS A O 1 ATOM 7326 C CB . LYS A 1 931 ? 55.762 73.594 -22.216 1.00 11.06 ? 931 LYS A CB 1 ATOM 7327 C CG . LYS A 1 931 ? 54.933 72.927 -23.304 1.00 11.20 ? 931 LYS A CG 1 ATOM 7328 C CD . LYS A 1 931 ? 54.013 73.946 -23.995 1.00 14.41 ? 931 LYS A CD 1 ATOM 7329 C CE . LYS A 1 931 ? 53.178 74.713 -22.968 1.00 15.94 ? 931 LYS A CE 1 ATOM 7330 N NZ . LYS A 1 931 ? 52.199 75.697 -23.501 1.00 16.77 ? 931 LYS A NZ 1 ATOM 7331 N N . PHE A 1 932 ? 58.913 73.452 -21.055 1.00 10.09 ? 932 PHE A N 1 ATOM 7332 C CA . PHE A 1 932 ? 59.955 74.166 -20.337 1.00 9.84 ? 932 PHE A CA 1 ATOM 7333 C C . PHE A 1 932 ? 60.666 75.203 -21.222 1.00 8.14 ? 932 PHE A C 1 ATOM 7334 O O . PHE A 1 932 ? 61.046 74.880 -22.337 1.00 10.01 ? 932 PHE A O 1 ATOM 7335 C CB . PHE A 1 932 ? 61.035 73.169 -19.876 1.00 9.20 ? 932 PHE A CB 1 ATOM 7336 C CG . PHE A 1 932 ? 60.509 72.078 -18.947 1.00 9.45 ? 932 PHE A CG 1 ATOM 7337 C CD1 . PHE A 1 932 ? 59.964 70.902 -19.449 1.00 9.87 ? 932 PHE A CD1 1 ATOM 7338 C CD2 . PHE A 1 932 ? 60.615 72.251 -17.572 1.00 12.38 ? 932 PHE A CD2 1 ATOM 7339 C CE1 . PHE A 1 932 ? 59.523 69.864 -18.550 1.00 10.44 ? 932 PHE A CE1 1 ATOM 7340 C CE2 . PHE A 1 932 ? 60.178 71.235 -16.673 1.00 14.30 ? 932 PHE A CE2 1 ATOM 7341 C CZ . PHE A 1 932 ? 59.647 70.082 -17.172 1.00 12.08 ? 932 PHE A CZ 1 ATOM 7342 N N . ILE A 1 933 ? 60.859 76.405 -20.732 1.00 8.43 ? 933 ILE A N 1 ATOM 7343 C CA . ILE A 1 933 ? 61.564 77.480 -21.510 1.00 9.90 ? 933 ILE A CA 1 ATOM 7344 C C . ILE A 1 933 ? 62.892 77.726 -20.810 1.00 11.44 ? 933 ILE A C 1 ATOM 7345 O O . ILE A 1 933 ? 62.919 78.038 -19.586 1.00 9.84 ? 933 ILE A O 1 ATOM 7346 C CB . ILE A 1 933 ? 60.774 78.806 -21.461 1.00 10.67 ? 933 ILE A CB 1 ATOM 7347 C CG1 . ILE A 1 933 ? 59.343 78.565 -21.946 1.00 10.86 ? 933 ILE A CG1 1 ATOM 7348 C CG2 . ILE A 1 933 ? 61.437 79.852 -22.378 1.00 11.72 ? 933 ILE A CG2 1 ATOM 7349 C CD1 . ILE A 1 933 ? 58.379 79.737 -21.697 1.00 10.12 ? 933 ILE A CD1 1 ATOM 7350 N N . PHE A 1 934 ? 64.007 77.584 -21.542 1.00 10.77 ? 934 PHE A N 1 ATOM 7351 C CA . PHE A 1 934 ? 65.305 77.827 -20.938 1.00 12.75 ? 934 PHE A CA 1 ATOM 7352 C C . PHE A 1 934 ? 65.352 79.283 -20.459 1.00 14.10 ? 934 PHE A C 1 ATOM 7353 O O . PHE A 1 934 ? 65.031 80.245 -21.206 1.00 13.52 ? 934 PHE A O 1 ATOM 7354 C CB . PHE A 1 934 ? 66.410 77.581 -21.931 1.00 12.41 ? 934 PHE A CB 1 ATOM 7355 C CG . PHE A 1 934 ? 67.774 77.620 -21.300 1.00 14.57 ? 934 PHE A CG 1 ATOM 7356 C CD1 . PHE A 1 934 ? 68.167 76.640 -20.398 1.00 13.88 ? 934 PHE A CD1 1 ATOM 7357 C CD2 . PHE A 1 934 ? 68.650 78.669 -21.572 1.00 15.97 ? 934 PHE A CD2 1 ATOM 7358 C CE1 . PHE A 1 934 ? 69.430 76.722 -19.770 1.00 16.80 ? 934 PHE A CE1 1 ATOM 7359 C CE2 . PHE A 1 934 ? 69.921 78.772 -20.959 1.00 16.24 ? 934 PHE A CE2 1 ATOM 7360 C CZ . PHE A 1 934 ? 70.303 77.802 -20.062 1.00 17.68 ? 934 PHE A CZ 1 ATOM 7361 N N . ALA A 1 935 ? 65.772 79.488 -19.224 1.00 13.83 ? 935 ALA A N 1 ATOM 7362 C CA . ALA A 1 935 ? 65.715 80.826 -18.685 1.00 17.68 ? 935 ALA A CA 1 ATOM 7363 C C . ALA A 1 935 ? 66.842 81.839 -18.942 1.00 21.62 ? 935 ALA A C 1 ATOM 7364 O O . ALA A 1 935 ? 66.586 83.037 -18.874 1.00 23.36 ? 935 ALA A O 1 ATOM 7365 C CB . ALA A 1 935 ? 65.420 80.779 -17.168 1.00 18.60 ? 935 ALA A CB 1 ATOM 7366 N N . GLU A 1 936 ? 68.059 81.358 -19.215 1.00 21.06 ? 936 GLU A N 1 ATOM 7367 C CA . GLU A 1 936 ? 69.215 82.228 -19.491 1.00 21.37 ? 936 GLU A CA 1 ATOM 7368 C C . GLU A 1 936 ? 69.319 82.411 -21.014 1.00 20.63 ? 936 GLU A C 1 ATOM 7369 O O . GLU A 1 936 ? 68.527 81.843 -21.793 1.00 21.05 ? 936 GLU A O 1 ATOM 7370 C CB . GLU A 1 936 ? 70.496 81.544 -19.004 1.00 23.79 ? 936 GLU A CB 1 ATOM 7371 C CG . GLU A 1 936 ? 70.699 81.519 -17.526 1.00 29.57 ? 936 GLU A CG 1 ATOM 7372 C CD . GLU A 1 936 ? 69.697 82.356 -16.815 1.00 32.53 ? 936 GLU A CD 1 ATOM 7373 O OE1 . GLU A 1 936 ? 68.501 81.940 -16.783 1.00 37.81 ? 936 GLU A OE1 1 ATOM 7374 O OE2 . GLU A 1 936 ? 70.076 83.426 -16.290 1.00 34.97 ? 936 GLU A OE2 1 ATOM 7375 N N . ASN A 1 937 ? 70.315 83.187 -21.460 1.00 20.81 ? 937 ASN A N 1 ATOM 7376 C CA . ASN A 1 937 ? 70.476 83.403 -22.903 1.00 21.28 ? 937 ASN A CA 1 ATOM 7377 C C . ASN A 1 937 ? 71.016 82.222 -23.643 1.00 21.08 ? 937 ASN A C 1 ATOM 7378 O O . ASN A 1 937 ? 70.605 81.917 -24.761 1.00 22.05 ? 937 ASN A O 1 ATOM 7379 C CB . ASN A 1 937 ? 71.422 84.567 -23.169 1.00 22.47 ? 937 ASN A CB 1 ATOM 7380 C CG . ASN A 1 937 ? 70.799 85.896 -22.826 1.00 24.46 ? 937 ASN A CG 1 ATOM 7381 O OD1 . ASN A 1 937 ? 69.572 86.000 -22.640 1.00 26.44 ? 937 ASN A OD1 1 ATOM 7382 N ND2 . ASN A 1 937 ? 71.624 86.926 -22.735 1.00 27.37 ? 937 ASN A ND2 1 ATOM 7383 N N . GLU A 1 938 ? 71.967 81.555 -23.015 1.00 20.43 ? 938 GLU A N 1 ATOM 7384 C CA . GLU A 1 938 ? 72.600 80.431 -23.666 1.00 21.81 ? 938 GLU A CA 1 ATOM 7385 C C . GLU A 1 938 ? 72.720 79.156 -22.814 1.00 19.36 ? 938 GLU A C 1 ATOM 7386 O O . GLU A 1 938 ? 73.252 79.228 -21.709 1.00 20.35 ? 938 GLU A O 1 ATOM 7387 C CB . GLU A 1 938 ? 73.989 80.860 -24.128 1.00 23.19 ? 938 GLU A CB 1 ATOM 7388 C CG . GLU A 1 938 ? 74.659 79.771 -24.901 1.00 29.08 ? 938 GLU A CG 1 ATOM 7389 C CD . GLU A 1 938 ? 76.080 80.124 -25.218 1.00 32.34 ? 938 GLU A CD 1 ATOM 7390 O OE1 . GLU A 1 938 ? 76.624 81.058 -24.561 1.00 33.91 ? 938 GLU A OE1 1 ATOM 7391 O OE2 . GLU A 1 938 ? 76.647 79.445 -26.107 1.00 33.79 ? 938 GLU A OE2 1 ATOM 7392 N N . TRP A 1 939 ? 72.291 78.018 -23.381 1.00 18.48 ? 939 TRP A N 1 ATOM 7393 C CA . TRP A 1 939 ? 72.334 76.715 -22.696 1.00 18.19 ? 939 TRP A CA 1 ATOM 7394 C C . TRP A 1 939 ? 73.517 75.964 -23.267 1.00 17.58 ? 939 TRP A C 1 ATOM 7395 O O . TRP A 1 939 ? 73.424 75.406 -24.335 1.00 19.79 ? 939 TRP A O 1 ATOM 7396 C CB . TRP A 1 939 ? 71.014 75.952 -22.954 1.00 17.07 ? 939 TRP A CB 1 ATOM 7397 C CG . TRP A 1 939 ? 70.914 74.529 -22.392 1.00 14.13 ? 939 TRP A CG 1 ATOM 7398 C CD1 . TRP A 1 939 ? 71.826 73.861 -21.586 1.00 14.47 ? 939 TRP A CD1 1 ATOM 7399 C CD2 . TRP A 1 939 ? 69.848 73.608 -22.633 1.00 15.67 ? 939 TRP A CD2 1 ATOM 7400 N NE1 . TRP A 1 939 ? 71.369 72.583 -21.325 1.00 17.18 ? 939 TRP A NE1 1 ATOM 7401 C CE2 . TRP A 1 939 ? 70.161 72.398 -21.946 1.00 14.44 ? 939 TRP A CE2 1 ATOM 7402 C CE3 . TRP A 1 939 ? 68.651 73.688 -23.368 1.00 13.77 ? 939 TRP A CE3 1 ATOM 7403 C CZ2 . TRP A 1 939 ? 69.324 71.272 -21.966 1.00 15.34 ? 939 TRP A CZ2 1 ATOM 7404 C CZ3 . TRP A 1 939 ? 67.801 72.560 -23.397 1.00 13.63 ? 939 TRP A CZ3 1 ATOM 7405 C CH2 . TRP A 1 939 ? 68.145 71.369 -22.698 1.00 12.55 ? 939 TRP A CH2 1 ATOM 7406 N N . ILE A 1 940 ? 74.635 75.954 -22.551 1.00 19.34 ? 940 ILE A N 1 ATOM 7407 C CA . ILE A 1 940 ? 75.839 75.266 -23.065 1.00 21.13 ? 940 ILE A CA 1 ATOM 7408 C C . ILE A 1 940 ? 75.727 73.777 -22.761 1.00 20.15 ? 940 ILE A C 1 ATOM 7409 O O . ILE A 1 940 ? 75.314 73.416 -21.666 1.00 21.97 ? 940 ILE A O 1 ATOM 7410 C CB . ILE A 1 940 ? 77.117 75.841 -22.398 1.00 22.31 ? 940 ILE A CB 1 ATOM 7411 C CG1 . ILE A 1 940 ? 77.324 77.291 -22.830 1.00 24.01 ? 940 ILE A CG1 1 ATOM 7412 C CG2 . ILE A 1 940 ? 78.365 75.056 -22.765 1.00 23.79 ? 940 ILE A CG2 1 ATOM 7413 C CD1 . ILE A 1 940 ? 76.975 78.321 -21.690 1.00 25.02 ? 940 ILE A CD1 1 ATOM 7414 N N . GLY A 1 941 ? 76.016 72.942 -23.755 1.00 20.89 ? 941 GLY A N 1 ATOM 7415 C CA . GLY A 1 941 ? 75.952 71.500 -23.564 1.00 19.85 ? 941 GLY A CA 1 ATOM 7416 C C . GLY A 1 941 ? 74.581 70.892 -23.856 1.00 20.13 ? 941 GLY A C 1 ATOM 7417 O O . GLY A 1 941 ? 74.358 69.688 -23.661 1.00 19.78 ? 941 GLY A O 1 ATOM 7418 N N . ALA A 1 942 ? 73.675 71.699 -24.406 1.00 18.59 ? 942 ALA A N 1 ATOM 7419 C CA . ALA A 1 942 ? 72.336 71.218 -24.732 1.00 17.94 ? 942 ALA A CA 1 ATOM 7420 C C . ALA A 1 942 ? 72.273 70.011 -25.610 1.00 18.96 ? 942 ALA A C 1 ATOM 7421 O O . ALA A 1 942 ? 73.026 69.906 -26.584 1.00 19.32 ? 942 ALA A O 1 ATOM 7422 C CB . ALA A 1 942 ? 71.534 72.368 -25.367 1.00 17.56 ? 942 ALA A CB 1 ATOM 7423 N N . GLN A 1 943 ? 71.335 69.120 -25.320 1.00 19.31 ? 943 GLN A N 1 ATOM 7424 C CA . GLN A 1 943 ? 71.129 67.904 -26.073 1.00 19.43 ? 943 GLN A CA 1 ATOM 7425 C C . GLN A 1 943 ? 69.723 67.877 -26.654 1.00 17.50 ? 943 GLN A C 1 ATOM 7426 O O . GLN A 1 943 ? 68.828 68.521 -26.118 1.00 19.21 ? 943 GLN A O 1 ATOM 7427 C CB . GLN A 1 943 ? 71.380 66.720 -25.150 1.00 22.41 ? 943 GLN A CB 1 ATOM 7428 C CG . GLN A 1 943 ? 72.718 66.845 -24.448 1.00 26.01 ? 943 GLN A CG 1 ATOM 7429 C CD . GLN A 1 943 ? 73.092 65.543 -23.796 1.00 28.09 ? 943 GLN A CD 1 ATOM 7430 O OE1 . GLN A 1 943 ? 72.280 64.971 -23.027 1.00 30.84 ? 943 GLN A OE1 1 ATOM 7431 N NE2 . GLN A 1 943 ? 74.300 65.046 -24.087 1.00 29.15 ? 943 GLN A NE2 1 ATOM 7432 N N . GLY A 1 944 ? 69.518 67.140 -27.744 1.00 18.19 ? 944 GLY A N 1 ATOM 7433 C CA . GLY A 1 944 ? 68.231 67.197 -28.419 1.00 18.61 ? 944 GLY A CA 1 ATOM 7434 C C . GLY A 1 944 ? 67.102 66.335 -27.955 1.00 18.48 ? 944 GLY A C 1 ATOM 7435 O O . GLY A 1 944 ? 65.959 66.685 -28.160 1.00 19.52 ? 944 GLY A O 1 ATOM 7436 N N . GLN A 1 945 ? 67.411 65.231 -27.294 1.00 18.33 ? 945 GLN A N 1 ATOM 7437 C CA . GLN A 1 945 ? 66.347 64.296 -26.920 1.00 17.23 ? 945 GLN A CA 1 ATOM 7438 C C . GLN A 1 945 ? 66.809 63.394 -25.772 1.00 17.44 ? 945 GLN A C 1 ATOM 7439 O O . GLN A 1 945 ? 67.999 63.172 -25.578 1.00 17.99 ? 945 GLN A O 1 ATOM 7440 C CB . GLN A 1 945 ? 66.050 63.449 -28.154 1.00 19.30 ? 945 GLN A CB 1 ATOM 7441 C CG . GLN A 1 945 ? 64.866 62.487 -28.123 1.00 22.29 ? 945 GLN A CG 1 ATOM 7442 C CD . GLN A 1 945 ? 64.764 61.638 -29.413 1.00 23.16 ? 945 GLN A CD 1 ATOM 7443 O OE1 . GLN A 1 945 ? 63.984 61.964 -30.314 1.00 25.50 ? 945 GLN A OE1 1 ATOM 7444 N NE2 . GLN A 1 945 ? 65.549 60.553 -29.499 1.00 23.57 ? 945 GLN A NE2 1 ATOM 7445 N N . PHE A 1 946 ? 65.848 62.878 -25.019 1.00 14.81 ? 946 PHE A N 1 ATOM 7446 C CA . PHE A 1 946 ? 66.140 61.930 -23.949 1.00 14.38 ? 946 PHE A CA 1 ATOM 7447 C C . PHE A 1 946 ? 65.057 60.883 -24.072 1.00 13.88 ? 946 PHE A C 1 ATOM 7448 O O . PHE A 1 946 ? 63.879 61.228 -24.296 1.00 13.03 ? 946 PHE A O 1 ATOM 7449 C CB . PHE A 1 946 ? 66.117 62.593 -22.554 1.00 14.46 ? 946 PHE A CB 1 ATOM 7450 C CG . PHE A 1 946 ? 66.022 61.588 -21.407 1.00 15.58 ? 946 PHE A CG 1 ATOM 7451 C CD1 . PHE A 1 946 ? 67.088 60.746 -21.114 1.00 16.01 ? 946 PHE A CD1 1 ATOM 7452 C CD2 . PHE A 1 946 ? 64.819 61.433 -20.708 1.00 16.98 ? 946 PHE A CD2 1 ATOM 7453 C CE1 . PHE A 1 946 ? 66.955 59.734 -20.120 1.00 17.65 ? 946 PHE A CE1 1 ATOM 7454 C CE2 . PHE A 1 946 ? 64.669 60.445 -19.735 1.00 16.22 ? 946 PHE A CE2 1 ATOM 7455 C CZ . PHE A 1 946 ? 65.730 59.589 -19.433 1.00 15.26 ? 946 PHE A CZ 1 ATOM 7456 N N . GLY A 1 947 ? 65.421 59.609 -23.990 1.00 13.96 ? 947 GLY A N 1 ATOM 7457 C CA . GLY A 1 947 ? 64.405 58.581 -24.002 1.00 13.71 ? 947 GLY A CA 1 ATOM 7458 C C . GLY A 1 947 ? 64.085 57.965 -25.350 1.00 15.81 ? 947 GLY A C 1 ATOM 7459 O O . GLY A 1 947 ? 63.165 57.140 -25.475 1.00 14.46 ? 947 GLY A O 1 ATOM 7460 N N . GLY A 1 948 ? 64.859 58.320 -26.370 1.00 16.03 ? 948 GLY A N 1 ATOM 7461 C CA . GLY A 1 948 ? 64.605 57.729 -27.667 1.00 17.86 ? 948 GLY A CA 1 ATOM 7462 C C . GLY A 1 948 ? 64.648 56.212 -27.663 1.00 17.24 ? 948 GLY A C 1 ATOM 7463 O O . GLY A 1 948 ? 64.013 55.586 -28.495 1.00 19.61 ? 948 GLY A O 1 ATOM 7464 N N . ASP A 1 949 ? 65.375 55.607 -26.724 1.00 18.26 ? 949 ASP A N 1 ATOM 7465 C CA . ASP A 1 949 ? 65.430 54.165 -26.676 1.00 19.46 ? 949 ASP A CA 1 ATOM 7466 C C . ASP A 1 949 ? 64.419 53.531 -25.707 1.00 18.77 ? 949 ASP A C 1 ATOM 7467 O O . ASP A 1 949 ? 64.421 52.316 -25.484 1.00 17.79 ? 949 ASP A O 1 ATOM 7468 C CB . ASP A 1 949 ? 66.856 53.677 -26.376 1.00 21.89 ? 949 ASP A CB 1 ATOM 7469 C CG . ASP A 1 949 ? 67.375 54.155 -25.029 1.00 23.39 ? 949 ASP A CG 1 ATOM 7470 O OD1 . ASP A 1 949 ? 66.721 54.970 -24.340 1.00 25.23 ? 949 ASP A OD1 1 ATOM 7471 O OD2 . ASP A 1 949 ? 68.465 53.697 -24.633 1.00 29.03 ? 949 ASP A OD2 1 ATOM 7472 N N . HIS A 1 950 ? 63.544 54.347 -25.122 1.00 17.45 ? 950 HIS A N 1 ATOM 7473 C CA . HIS A 1 950 ? 62.513 53.782 -24.249 1.00 16.75 ? 950 HIS A CA 1 ATOM 7474 C C . HIS A 1 950 ? 61.464 53.026 -25.061 1.00 17.28 ? 950 HIS A C 1 ATOM 7475 O O . HIS A 1 950 ? 61.064 53.453 -26.143 1.00 16.83 ? 950 HIS A O 1 ATOM 7476 C CB . HIS A 1 950 ? 61.812 54.886 -23.473 1.00 14.78 ? 950 HIS A CB 1 ATOM 7477 C CG . HIS A 1 950 ? 62.685 55.591 -22.492 1.00 13.24 ? 950 HIS A CG 1 ATOM 7478 N ND1 . HIS A 1 950 ? 62.314 56.772 -21.883 1.00 12.23 ? 950 HIS A ND1 1 ATOM 7479 C CD2 . HIS A 1 950 ? 63.927 55.293 -22.012 1.00 13.42 ? 950 HIS A CD2 1 ATOM 7480 C CE1 . HIS A 1 950 ? 63.274 57.166 -21.070 1.00 15.28 ? 950 HIS A CE1 1 ATOM 7481 N NE2 . HIS A 1 950 ? 64.263 56.286 -21.127 1.00 13.55 ? 950 HIS A NE2 1 ATOM 7482 N N . PRO A 1 951 ? 60.987 51.878 -24.555 1.00 16.55 ? 951 PRO A N 1 ATOM 7483 C CA . PRO A 1 951 ? 59.987 51.180 -25.348 1.00 15.50 ? 951 PRO A CA 1 ATOM 7484 C C . PRO A 1 951 ? 58.684 51.971 -25.442 1.00 14.24 ? 951 PRO A C 1 ATOM 7485 O O . PRO A 1 951 ? 58.282 52.634 -24.470 1.00 15.47 ? 951 PRO A O 1 ATOM 7486 C CB . PRO A 1 951 ? 59.762 49.841 -24.603 1.00 17.98 ? 951 PRO A CB 1 ATOM 7487 C CG . PRO A 1 951 ? 60.977 49.682 -23.749 1.00 17.99 ? 951 PRO A CG 1 ATOM 7488 C CD . PRO A 1 951 ? 61.376 51.103 -23.357 1.00 16.43 ? 951 PRO A CD 1 ATOM 7489 N N . SER A 1 952 ? 58.039 51.862 -26.600 1.00 14.25 ? 952 SER A N 1 ATOM 7490 C CA . SER A 1 952 ? 56.762 52.535 -26.836 1.00 13.70 ? 952 SER A CA 1 ATOM 7491 C C . SER A 1 952 ? 55.713 51.445 -26.672 1.00 12.26 ? 952 SER A C 1 ATOM 7492 O O . SER A 1 952 ? 55.453 50.639 -27.556 1.00 15.39 ? 952 SER A O 1 ATOM 7493 C CB . SER A 1 952 ? 56.750 53.108 -28.239 1.00 13.42 ? 952 SER A CB 1 ATOM 7494 O OG . SER A 1 952 ? 55.695 54.027 -28.396 1.00 13.43 ? 952 SER A OG 1 ATOM 7495 N N . ALA A 1 953 ? 55.113 51.448 -25.482 1.00 14.38 ? 953 ALA A N 1 ATOM 7496 C CA . ALA A 1 953 ? 54.151 50.437 -25.071 1.00 13.42 ? 953 ALA A CA 1 ATOM 7497 C C . ALA A 1 953 ? 52.784 50.572 -25.707 1.00 12.97 ? 953 ALA A C 1 ATOM 7498 O O . ALA A 1 953 ? 52.403 51.667 -26.185 1.00 12.77 ? 953 ALA A O 1 ATOM 7499 C CB . ALA A 1 953 ? 54.053 50.511 -23.530 1.00 14.54 ? 953 ALA A CB 1 ATOM 7500 N N . ARG A 1 954 ? 52.028 49.481 -25.685 1.00 12.75 ? 954 ARG A N 1 ATOM 7501 C CA . ARG A 1 954 ? 50.691 49.446 -26.268 1.00 13.32 ? 954 ARG A CA 1 ATOM 7502 C C . ARG A 1 954 ? 49.870 50.573 -25.664 1.00 12.60 ? 954 ARG A C 1 ATOM 7503 O O . ARG A 1 954 ? 49.971 50.893 -24.480 1.00 12.29 ? 954 ARG A O 1 ATOM 7504 C CB . ARG A 1 954 ? 50.001 48.079 -26.088 1.00 14.64 ? 954 ARG A CB 1 ATOM 7505 C CG . ARG A 1 954 ? 48.720 47.974 -26.928 1.00 19.80 ? 954 ARG A CG 1 ATOM 7506 C CD . ARG A 1 954 ? 48.341 46.536 -27.261 1.00 24.24 ? 954 ARG A CD 1 ATOM 7507 N NE . ARG A 1 954 ? 47.708 45.819 -26.162 1.00 28.24 ? 954 ARG A NE 1 ATOM 7508 C CZ . ARG A 1 954 ? 46.403 45.608 -26.052 1.00 29.57 ? 954 ARG A CZ 1 ATOM 7509 N NH1 . ARG A 1 954 ? 45.570 46.086 -26.981 1.00 32.01 ? 954 ARG A NH1 1 ATOM 7510 N NH2 . ARG A 1 954 ? 45.923 44.858 -25.056 1.00 29.45 ? 954 ARG A NH2 1 ATOM 7511 N N . GLU A 1 955 ? 49.001 51.158 -26.478 1.00 12.37 ? 955 GLU A N 1 ATOM 7512 C CA . GLU A 1 955 ? 48.281 52.366 -26.078 1.00 11.23 ? 955 GLU A CA 1 ATOM 7513 C C . GLU A 1 955 ? 47.391 52.285 -24.822 1.00 11.06 ? 955 GLU A C 1 ATOM 7514 O O . GLU A 1 955 ? 47.127 53.324 -24.218 1.00 12.29 ? 955 GLU A O 1 ATOM 7515 C CB . GLU A 1 955 ? 47.413 52.849 -27.233 1.00 15.26 ? 955 GLU A CB 1 ATOM 7516 C CG . GLU A 1 955 ? 46.254 51.907 -27.571 1.00 18.16 ? 955 GLU A CG 1 ATOM 7517 C CD . GLU A 1 955 ? 45.315 52.445 -28.649 1.00 20.85 ? 955 GLU A CD 1 ATOM 7518 O OE1 . GLU A 1 955 ? 45.125 53.678 -28.752 1.00 20.42 ? 955 GLU A OE1 1 ATOM 7519 O OE2 . GLU A 1 955 ? 44.720 51.613 -29.380 1.00 20.19 ? 955 GLU A OE2 1 ATOM 7520 N N . ASP A 1 956 ? 46.926 51.079 -24.471 1.00 10.92 ? 956 ASP A N 1 ATOM 7521 C CA . ASP A 1 956 ? 46.049 50.945 -23.306 1.00 10.93 ? 956 ASP A CA 1 ATOM 7522 C C . ASP A 1 956 ? 46.884 50.817 -22.017 1.00 11.41 ? 956 ASP A C 1 ATOM 7523 O O . ASP A 1 956 ? 46.331 50.742 -20.898 1.00 11.65 ? 956 ASP A O 1 ATOM 7524 C CB . ASP A 1 956 ? 45.094 49.727 -23.454 1.00 12.34 ? 956 ASP A CB 1 ATOM 7525 C CG . ASP A 1 956 ? 45.786 48.419 -23.768 1.00 14.10 ? 956 ASP A CG 1 ATOM 7526 O OD1 . ASP A 1 956 ? 47.003 48.336 -23.947 1.00 15.89 ? 956 ASP A OD1 1 ATOM 7527 O OD2 . ASP A 1 956 ? 45.051 47.439 -23.861 1.00 14.57 ? 956 ASP A OD2 1 ATOM 7528 N N . LEU A 1 957 ? 48.216 50.813 -22.150 1.00 11.69 ? 957 LEU A N 1 ATOM 7529 C CA . LEU A 1 957 ? 49.055 50.651 -20.965 1.00 11.74 ? 957 LEU A CA 1 ATOM 7530 C C . LEU A 1 957 ? 49.662 51.967 -20.504 1.00 9.69 ? 957 LEU A C 1 ATOM 7531 O O . LEU A 1 957 ? 50.139 52.789 -21.318 1.00 10.62 ? 957 LEU A O 1 ATOM 7532 C CB . LEU A 1 957 ? 50.188 49.663 -21.251 1.00 11.09 ? 957 LEU A CB 1 ATOM 7533 C CG . LEU A 1 957 ? 51.048 49.111 -20.105 1.00 15.37 ? 957 LEU A CG 1 ATOM 7534 C CD1 . LEU A 1 957 ? 50.148 48.140 -19.252 1.00 17.05 ? 957 LEU A CD1 1 ATOM 7535 C CD2 . LEU A 1 957 ? 52.289 48.296 -20.670 1.00 16.69 ? 957 LEU A CD2 1 ATOM 7536 N N . ASP A 1 958 ? 49.719 52.175 -19.194 1.00 9.17 ? 958 ASP A N 1 ATOM 7537 C CA . ASP A 1 958 ? 50.327 53.391 -18.665 1.00 8.49 ? 958 ASP A CA 1 ATOM 7538 C C . ASP A 1 958 ? 51.243 53.075 -17.478 1.00 9.68 ? 958 ASP A C 1 ATOM 7539 O O . ASP A 1 958 ? 50.979 52.120 -16.720 1.00 8.83 ? 958 ASP A O 1 ATOM 7540 C CB . ASP A 1 958 ? 49.224 54.403 -18.233 1.00 9.49 ? 958 ASP A CB 1 ATOM 7541 C CG . ASP A 1 958 ? 49.771 55.811 -17.936 1.00 11.16 ? 958 ASP A CG 1 ATOM 7542 O OD1 . ASP A 1 958 ? 50.862 56.136 -18.442 1.00 9.92 ? 958 ASP A OD1 1 ATOM 7543 O OD2 . ASP A 1 958 ? 49.113 56.623 -17.199 1.00 11.69 ? 958 ASP A OD2 1 ATOM 7544 N N . VAL A 1 959 ? 52.288 53.891 -17.313 1.00 7.35 ? 959 VAL A N 1 ATOM 7545 C CA . VAL A 1 959 ? 53.174 53.817 -16.153 1.00 9.00 ? 959 VAL A CA 1 ATOM 7546 C C . VAL A 1 959 ? 52.629 54.944 -15.266 1.00 9.12 ? 959 VAL A C 1 ATOM 7547 O O . VAL A 1 959 ? 53.021 56.122 -15.362 1.00 9.32 ? 959 VAL A O 1 ATOM 7548 C CB . VAL A 1 959 ? 54.636 54.070 -16.549 1.00 10.07 ? 959 VAL A CB 1 ATOM 7549 C CG1 . VAL A 1 959 ? 55.501 54.228 -15.285 1.00 9.76 ? 959 VAL A CG1 1 ATOM 7550 C CG2 . VAL A 1 959 ? 55.184 52.898 -17.370 1.00 10.44 ? 959 VAL A CG2 1 ATOM 7551 N N . SER A 1 960 ? 51.634 54.590 -14.450 1.00 9.17 ? 960 SER A N 1 ATOM 7552 C CA . SER A 1 960 ? 50.935 55.568 -13.603 1.00 9.82 ? 960 SER A CA 1 ATOM 7553 C C . SER A 1 960 ? 51.849 56.317 -12.637 1.00 9.01 ? 960 SER A C 1 ATOM 7554 O O . SER A 1 960 ? 51.699 57.512 -12.411 1.00 8.05 ? 960 SER A O 1 ATOM 7555 C CB . SER A 1 960 ? 49.806 54.876 -12.818 1.00 7.95 ? 960 SER A CB 1 ATOM 7556 O OG . SER A 1 960 ? 49.000 54.106 -13.666 1.00 11.09 ? 960 SER A OG 1 ATOM 7557 N N . VAL A 1 961 ? 52.832 55.594 -12.078 1.00 8.09 ? 961 VAL A N 1 ATOM 7558 C CA . VAL A 1 961 ? 53.813 56.098 -11.136 1.00 10.22 ? 961 VAL A CA 1 ATOM 7559 C C . VAL A 1 961 ? 55.183 55.482 -11.458 1.00 8.49 ? 961 VAL A C 1 ATOM 7560 O O . VAL A 1 961 ? 55.311 54.269 -11.777 1.00 9.46 ? 961 VAL A O 1 ATOM 7561 C CB . VAL A 1 961 ? 53.470 55.595 -9.734 1.00 9.43 ? 961 VAL A CB 1 ATOM 7562 C CG1 . VAL A 1 961 ? 54.544 56.054 -8.692 1.00 10.71 ? 961 VAL A CG1 1 ATOM 7563 C CG2 . VAL A 1 961 ? 52.076 56.109 -9.317 1.00 7.72 ? 961 VAL A CG2 1 ATOM 7564 N N . MET A 1 962 ? 56.202 56.328 -11.392 1.00 9.30 ? 962 MET A N 1 ATOM 7565 C CA . MET A 1 962 ? 57.596 55.903 -11.448 1.00 6.55 ? 962 MET A CA 1 ATOM 7566 C C . MET A 1 962 ? 58.133 56.741 -10.283 1.00 7.81 ? 962 MET A C 1 ATOM 7567 O O . MET A 1 962 ? 58.065 58.004 -10.281 1.00 8.07 ? 962 MET A O 1 ATOM 7568 C CB . MET A 1 962 ? 58.288 56.278 -12.767 1.00 8.46 ? 962 MET A CB 1 ATOM 7569 C CG . MET A 1 962 ? 59.791 56.028 -12.665 1.00 10.06 ? 962 MET A CG 1 ATOM 7570 S SD . MET A 1 962 ? 60.588 56.350 -14.308 1.00 10.52 ? 962 MET A SD 1 ATOM 7571 C CE . MET A 1 962 ? 62.353 55.850 -14.012 1.00 8.79 ? 962 MET A CE 1 ATOM 7572 N N . ARG A 1 963 ? 58.735 56.069 -9.295 1.00 9.48 ? 963 ARG A N 1 ATOM 7573 C CA . ARG A 1 963 ? 59.233 56.716 -8.099 1.00 8.44 ? 963 ARG A CA 1 ATOM 7574 C C . ARG A 1 963 ? 60.499 56.059 -7.555 1.00 8.78 ? 963 ARG A C 1 ATOM 7575 O O . ARG A 1 963 ? 60.465 54.879 -7.230 1.00 9.68 ? 963 ARG A O 1 ATOM 7576 C CB . ARG A 1 963 ? 58.168 56.666 -6.934 1.00 6.66 ? 963 ARG A CB 1 ATOM 7577 C CG . ARG A 1 963 ? 58.661 57.273 -5.627 1.00 11.64 ? 963 ARG A CG 1 ATOM 7578 C CD . ARG A 1 963 ? 57.586 57.216 -4.470 1.00 12.38 ? 963 ARG A CD 1 ATOM 7579 N NE . ARG A 1 963 ? 56.354 57.894 -4.919 1.00 11.08 ? 963 ARG A NE 1 ATOM 7580 C CZ . ARG A 1 963 ? 55.134 57.373 -4.884 1.00 10.28 ? 963 ARG A CZ 1 ATOM 7581 N NH1 . ARG A 1 963 ? 54.871 56.164 -4.388 1.00 10.10 ? 963 ARG A NH1 1 ATOM 7582 N NH2 . ARG A 1 963 ? 54.181 58.043 -5.511 1.00 9.08 ? 963 ARG A NH2 1 ATOM 7583 N N . ARG A 1 964 ? 61.619 56.813 -7.468 1.00 10.35 ? 964 ARG A N 1 ATOM 7584 C CA . ARG A 1 964 ? 62.842 56.218 -6.834 1.00 9.60 ? 964 ARG A CA 1 ATOM 7585 C C . ARG A 1 964 ? 62.519 56.161 -5.331 1.00 10.42 ? 964 ARG A C 1 ATOM 7586 O O . ARG A 1 964 ? 62.071 57.109 -4.712 1.00 10.09 ? 964 ARG A O 1 ATOM 7587 C CB . ARG A 1 964 ? 64.041 57.134 -7.054 1.00 10.88 ? 964 ARG A CB 1 ATOM 7588 C CG . ARG A 1 964 ? 65.316 56.404 -6.595 1.00 10.06 ? 964 ARG A CG 1 ATOM 7589 C CD . ARG A 1 964 ? 66.641 57.083 -7.013 1.00 8.71 ? 964 ARG A CD 1 ATOM 7590 N NE . ARG A 1 964 ? 66.834 56.909 -8.420 1.00 11.59 ? 964 ARG A NE 1 ATOM 7591 C CZ . ARG A 1 964 ? 67.706 56.108 -9.013 1.00 12.61 ? 964 ARG A CZ 1 ATOM 7592 N NH1 . ARG A 1 964 ? 68.559 55.324 -8.316 1.00 15.69 ? 964 ARG A NH1 1 ATOM 7593 N NH2 . ARG A 1 964 ? 67.719 56.056 -10.347 1.00 12.35 ? 964 ARG A NH2 1 ATOM 7594 N N . LEU A 1 965 ? 62.739 54.990 -4.749 1.00 10.73 ? 965 LEU A N 1 ATOM 7595 C CA . LEU A 1 965 ? 62.371 54.745 -3.340 1.00 10.09 ? 965 LEU A CA 1 ATOM 7596 C C . LEU A 1 965 ? 63.516 54.860 -2.294 1.00 11.95 ? 965 LEU A C 1 ATOM 7597 O O . LEU A 1 965 ? 63.291 54.837 -1.080 1.00 12.96 ? 965 LEU A O 1 ATOM 7598 C CB . LEU A 1 965 ? 61.763 53.353 -3.207 1.00 11.49 ? 965 LEU A CB 1 ATOM 7599 C CG . LEU A 1 965 ? 60.594 53.078 -4.163 1.00 10.45 ? 965 LEU A CG 1 ATOM 7600 C CD1 . LEU A 1 965 ? 60.191 51.593 -4.129 1.00 10.84 ? 965 LEU A CD1 1 ATOM 7601 C CD2 . LEU A 1 965 ? 59.398 53.954 -3.763 1.00 13.07 ? 965 LEU A CD2 1 ATOM 7602 N N . THR A 1 966 ? 64.727 55.063 -2.824 1.00 11.50 ? 966 THR A N 1 ATOM 7603 C CA . THR A 1 966 ? 65.939 55.160 -2.024 1.00 11.35 ? 966 THR A CA 1 ATOM 7604 C C . THR A 1 966 ? 66.659 56.457 -2.220 1.00 12.29 ? 966 THR A C 1 ATOM 7605 O O . THR A 1 966 ? 66.690 56.993 -3.326 1.00 13.11 ? 966 THR A O 1 ATOM 7606 C CB . THR A 1 966 ? 66.994 54.041 -2.420 1.00 9.57 ? 966 THR A CB 1 ATOM 7607 O OG1 . THR A 1 966 ? 67.064 53.880 -3.851 1.00 11.80 ? 966 THR A OG1 1 ATOM 7608 C CG2 . THR A 1 966 ? 66.568 52.667 -1.823 1.00 11.65 ? 966 THR A CG2 1 ATOM 7609 N N . LYS A 1 967 ? 67.291 56.889 -1.140 1.00 12.71 ? 967 LYS A N 1 ATOM 7610 C CA . LYS A 1 967 ? 68.143 58.054 -1.165 1.00 14.97 ? 967 LYS A CA 1 ATOM 7611 C C . LYS A 1 967 ? 69.514 57.644 -1.742 1.00 14.21 ? 967 LYS A C 1 ATOM 7612 O O . LYS A 1 967 ? 69.808 56.458 -1.939 1.00 13.26 ? 967 LYS A O 1 ATOM 7613 C CB . LYS A 1 967 ? 68.290 58.637 0.238 1.00 16.37 ? 967 LYS A CB 1 ATOM 7614 C CG . LYS A 1 967 ? 67.037 59.358 0.711 1.00 21.93 ? 967 LYS A CG 1 ATOM 7615 C CD . LYS A 1 967 ? 67.216 59.832 2.124 1.00 25.34 ? 967 LYS A CD 1 ATOM 7616 C CE . LYS A 1 967 ? 65.911 60.258 2.709 1.00 28.21 ? 967 LYS A CE 1 ATOM 7617 N NZ . LYS A 1 967 ? 65.666 61.708 2.523 1.00 30.47 ? 967 LYS A NZ 1 ATOM 7618 N N . SER A 1 968 ? 70.339 58.648 -2.052 1.00 16.48 ? 968 SER A N 1 ATOM 7619 C CA . SER A 1 968 ? 71.620 58.397 -2.699 1.00 16.91 ? 968 SER A CA 1 ATOM 7620 C C . SER A 1 968 ? 72.639 57.579 -1.884 1.00 18.13 ? 968 SER A C 1 ATOM 7621 O O . SER A 1 968 ? 73.469 56.924 -2.464 1.00 19.43 ? 968 SER A O 1 ATOM 7622 C CB . SER A 1 968 ? 72.247 59.742 -3.132 1.00 19.78 ? 968 SER A CB 1 ATOM 7623 O OG . SER A 1 968 ? 72.610 60.501 -1.979 1.00 23.49 ? 968 SER A OG 1 ATOM 7624 N N . SER A 1 969 ? 72.557 57.577 -0.557 1.00 17.33 ? 969 SER A N 1 ATOM 7625 C CA . SER A 1 969 ? 73.568 56.802 0.200 1.00 19.23 ? 969 SER A CA 1 ATOM 7626 C C . SER A 1 969 ? 73.271 55.283 0.165 1.00 18.92 ? 969 SER A C 1 ATOM 7627 O O . SER A 1 969 ? 74.099 54.482 0.601 1.00 18.55 ? 969 SER A O 1 ATOM 7628 C CB . SER A 1 969 ? 73.571 57.287 1.631 1.00 22.17 ? 969 SER A CB 1 ATOM 7629 O OG . SER A 1 969 ? 72.452 56.703 2.267 1.00 27.65 ? 969 SER A OG 1 ATOM 7630 N N . ALA A 1 970 ? 72.109 54.847 -0.336 1.00 16.96 ? 970 ALA A N 1 ATOM 7631 C CA . ALA A 1 970 ? 71.805 53.424 -0.380 1.00 16.42 ? 970 ALA A CA 1 ATOM 7632 C C . ALA A 1 970 ? 72.656 52.658 -1.406 1.00 17.06 ? 970 ALA A C 1 ATOM 7633 O O . ALA A 1 970 ? 72.661 53.006 -2.588 1.00 17.73 ? 970 ALA A O 1 ATOM 7634 C CB . ALA A 1 970 ? 70.281 53.206 -0.683 1.00 16.14 ? 970 ALA A CB 1 ATOM 7635 N N . LYS A 1 971 ? 73.422 51.647 -0.950 1.00 17.91 ? 971 LYS A N 1 ATOM 7636 C CA . LYS A 1 971 ? 74.201 50.844 -1.864 1.00 18.14 ? 971 LYS A CA 1 ATOM 7637 C C . LYS A 1 971 ? 73.296 50.236 -2.922 1.00 17.65 ? 971 LYS A C 1 ATOM 7638 O O . LYS A 1 971 ? 73.639 50.237 -4.078 1.00 17.67 ? 971 LYS A O 1 ATOM 7639 C CB . LYS A 1 971 ? 74.923 49.735 -1.082 1.00 20.74 ? 971 LYS A CB 1 ATOM 7640 C CG . LYS A 1 971 ? 76.017 49.057 -1.849 1.00 26.23 ? 971 LYS A CG 1 ATOM 7641 C CD . LYS A 1 971 ? 76.837 48.205 -0.854 1.00 28.73 ? 971 LYS A CD 1 ATOM 7642 C CE . LYS A 1 971 ? 78.187 47.725 -1.427 1.00 30.90 ? 971 LYS A CE 1 ATOM 7643 N NZ . LYS A 1 971 ? 79.171 48.812 -1.850 1.00 33.79 ? 971 LYS A NZ 1 ATOM 7644 N N . THR A 1 972 ? 72.147 49.685 -2.520 1.00 17.81 ? 972 THR A N 1 ATOM 7645 C CA . THR A 1 972 ? 71.221 49.111 -3.498 1.00 17.03 ? 972 THR A CA 1 ATOM 7646 C C . THR A 1 972 ? 70.075 50.118 -3.744 1.00 16.58 ? 972 THR A C 1 ATOM 7647 O O . THR A 1 972 ? 69.315 50.444 -2.811 1.00 15.87 ? 972 THR A O 1 ATOM 7648 C CB . THR A 1 972 ? 70.620 47.768 -3.042 1.00 19.65 ? 972 THR A CB 1 ATOM 7649 O OG1 . THR A 1 972 ? 71.698 46.853 -2.741 1.00 20.07 ? 972 THR A OG1 1 ATOM 7650 C CG2 . THR A 1 972 ? 69.769 47.138 -4.198 1.00 17.89 ? 972 THR A CG2 1 ATOM 7651 N N . GLN A 1 973 ? 70.023 50.674 -4.963 1.00 13.59 ? 973 GLN A N 1 ATOM 7652 C CA . GLN A 1 973 ? 68.982 51.646 -5.307 1.00 13.54 ? 973 GLN A CA 1 ATOM 7653 C C . GLN A 1 973 ? 67.730 50.860 -5.684 1.00 12.49 ? 973 GLN A C 1 ATOM 7654 O O . GLN A 1 973 ? 67.815 49.800 -6.250 1.00 13.06 ? 973 GLN A O 1 ATOM 7655 C CB . GLN A 1 973 ? 69.451 52.552 -6.485 1.00 11.36 ? 973 GLN A CB 1 ATOM 7656 C CG . GLN A 1 973 ? 70.528 53.557 -6.071 1.00 13.92 ? 973 GLN A CG 1 ATOM 7657 C CD . GLN A 1 973 ? 70.006 54.572 -5.065 1.00 14.36 ? 973 GLN A CD 1 ATOM 7658 O OE1 . GLN A 1 973 ? 68.983 55.240 -5.343 1.00 14.07 ? 973 GLN A OE1 1 ATOM 7659 N NE2 . GLN A 1 973 ? 70.658 54.720 -3.908 1.00 11.81 ? 973 GLN A NE2 1 ATOM 7660 N N . ARG A 1 974 ? 66.560 51.445 -5.365 1.00 13.82 ? 974 ARG A N 1 ATOM 7661 C CA . ARG A 1 974 ? 65.292 50.807 -5.689 1.00 12.51 ? 974 ARG A CA 1 ATOM 7662 C C . ARG A 1 974 ? 64.352 51.805 -6.385 1.00 10.53 ? 974 ARG A C 1 ATOM 7663 O O . ARG A 1 974 ? 64.294 52.973 -5.991 1.00 11.88 ? 974 ARG A O 1 ATOM 7664 C CB . ARG A 1 974 ? 64.611 50.243 -4.405 1.00 12.66 ? 974 ARG A CB 1 ATOM 7665 C CG . ARG A 1 974 ? 65.479 49.216 -3.641 1.00 14.02 ? 974 ARG A CG 1 ATOM 7666 C CD . ARG A 1 974 ? 64.907 48.832 -2.266 1.00 15.35 ? 974 ARG A CD 1 ATOM 7667 N NE . ARG A 1 974 ? 63.641 48.124 -2.410 1.00 18.34 ? 974 ARG A NE 1 ATOM 7668 C CZ . ARG A 1 974 ? 62.471 48.538 -1.916 1.00 18.48 ? 974 ARG A CZ 1 ATOM 7669 N NH1 . ARG A 1 974 ? 62.371 49.661 -1.241 1.00 18.42 ? 974 ARG A NH1 1 ATOM 7670 N NH2 . ARG A 1 974 ? 61.394 47.783 -2.074 1.00 18.50 ? 974 ARG A NH2 1 ATOM 7671 N N . VAL A 1 975 ? 63.695 51.330 -7.452 1.00 11.95 ? 975 VAL A N 1 ATOM 7672 C CA . VAL A 1 975 ? 62.757 52.236 -8.165 1.00 11.88 ? 975 VAL A CA 1 ATOM 7673 C C . VAL A 1 975 ? 61.442 51.525 -8.281 1.00 10.63 ? 975 VAL A C 1 ATOM 7674 O O . VAL A 1 975 ? 61.414 50.360 -8.720 1.00 10.59 ? 975 VAL A O 1 ATOM 7675 C CB . VAL A 1 975 ? 63.305 52.613 -9.591 1.00 14.17 ? 975 VAL A CB 1 ATOM 7676 C CG1 . VAL A 1 975 ? 62.276 53.531 -10.381 1.00 10.11 ? 975 VAL A CG1 1 ATOM 7677 C CG2 . VAL A 1 975 ? 64.635 53.363 -9.407 1.00 12.15 ? 975 VAL A CG2 1 ATOM 7678 N N . GLY A 1 976 ? 60.359 52.218 -7.919 1.00 12.37 ? 976 GLY A N 1 ATOM 7679 C CA . GLY A 1 976 ? 59.026 51.621 -8.003 1.00 8.94 ? 976 GLY A CA 1 ATOM 7680 C C . GLY A 1 976 ? 58.155 52.106 -9.140 1.00 8.88 ? 976 GLY A C 1 ATOM 7681 O O . GLY A 1 976 ? 58.231 53.294 -9.513 1.00 9.41 ? 976 GLY A O 1 ATOM 7682 N N . TYR A 1 977 ? 57.426 51.188 -9.710 1.00 8.32 ? 977 TYR A N 1 ATOM 7683 C CA . TYR A 1 977 ? 56.539 51.517 -10.827 1.00 8.22 ? 977 TYR A CA 1 ATOM 7684 C C . TYR A 1 977 ? 55.138 50.975 -10.576 1.00 7.96 ? 977 TYR A C 1 ATOM 7685 O O . TYR A 1 977 ? 55.009 49.879 -10.078 1.00 9.66 ? 977 TYR A O 1 ATOM 7686 C CB . TYR A 1 977 ? 57.012 50.850 -12.139 1.00 9.33 ? 977 TYR A CB 1 ATOM 7687 C CG . TYR A 1 977 ? 58.428 51.202 -12.524 1.00 11.94 ? 977 TYR A CG 1 ATOM 7688 C CD1 . TYR A 1 977 ? 59.527 50.519 -12.001 1.00 10.50 ? 977 TYR A CD1 1 ATOM 7689 C CD2 . TYR A 1 977 ? 58.664 52.240 -13.414 1.00 10.84 ? 977 TYR A CD2 1 ATOM 7690 C CE1 . TYR A 1 977 ? 60.825 50.869 -12.361 1.00 13.93 ? 977 TYR A CE1 1 ATOM 7691 C CE2 . TYR A 1 977 ? 59.960 52.592 -13.780 1.00 10.97 ? 977 TYR A CE2 1 ATOM 7692 C CZ . TYR A 1 977 ? 61.028 51.900 -13.240 1.00 11.93 ? 977 TYR A CZ 1 ATOM 7693 O OH . TYR A 1 977 ? 62.292 52.312 -13.584 1.00 13.64 ? 977 TYR A OH 1 ATOM 7694 N N . VAL A 1 978 ? 54.113 51.758 -10.931 1.00 7.98 ? 978 VAL A N 1 ATOM 7695 C CA . VAL A 1 978 ? 52.729 51.288 -10.891 1.00 7.79 ? 978 VAL A CA 1 ATOM 7696 C C . VAL A 1 978 ? 52.339 51.259 -12.363 1.00 9.85 ? 978 VAL A C 1 ATOM 7697 O O . VAL A 1 978 ? 52.467 52.287 -13.062 1.00 10.45 ? 978 VAL A O 1 ATOM 7698 C CB . VAL A 1 978 ? 51.806 52.208 -10.090 1.00 7.44 ? 978 VAL A CB 1 ATOM 7699 C CG1 . VAL A 1 978 ? 50.349 51.683 -10.260 1.00 8.43 ? 978 VAL A CG1 1 ATOM 7700 C CG2 . VAL A 1 978 ? 52.164 52.146 -8.558 1.00 7.51 ? 978 VAL A CG2 1 ATOM 7701 N N . LEU A 1 979 ? 51.945 50.085 -12.843 1.00 8.96 ? 979 LEU A N 1 ATOM 7702 C CA . LEU A 1 979 ? 51.543 49.881 -14.234 1.00 10.46 ? 979 LEU A CA 1 ATOM 7703 C C . LEU A 1 979 ? 50.064 49.631 -14.222 1.00 10.90 ? 979 LEU A C 1 ATOM 7704 O O A LEU A 1 979 ? 49.551 48.883 -13.389 0.50 11.81 ? 979 LEU A O 1 ATOM 7705 O O B LEU A 1 979 ? 49.597 48.538 -13.710 0.50 10.99 ? 979 LEU A O 1 ATOM 7706 C CB . LEU A 1 979 ? 52.310 48.664 -14.806 1.00 12.14 ? 979 LEU A CB 1 ATOM 7707 C CG A LEU A 1 979 ? 52.238 48.217 -16.280 0.50 14.18 ? 979 LEU A CG 1 ATOM 7708 C CG B LEU A 1 979 ? 52.835 48.557 -16.175 0.50 15.73 ? 979 LEU A CG 1 ATOM 7709 C CD1 A LEU A 1 979 ? 52.982 49.234 -17.127 0.50 14.85 ? 979 LEU A CD1 1 ATOM 7710 C CD1 B LEU A 1 979 ? 53.726 49.753 -16.371 0.50 12.70 ? 979 LEU A CD1 1 ATOM 7711 C CD2 A LEU A 1 979 ? 52.886 46.831 -16.450 0.50 15.41 ? 979 LEU A CD2 1 ATOM 7712 C CD2 B LEU A 1 979 ? 53.582 47.233 -16.495 0.50 15.53 ? 979 LEU A CD2 1 ATOM 7713 N N . HIS A 1 980 ? 49.364 50.295 -15.123 1.00 10.12 ? 980 HIS A N 1 ATOM 7714 C CA . HIS A 1 980 ? 47.942 50.136 -15.237 1.00 9.93 ? 980 HIS A CA 1 ATOM 7715 C C . HIS A 1 980 ? 47.544 49.921 -16.692 1.00 12.01 ? 980 HIS A C 1 ATOM 7716 O O . HIS A 1 980 ? 48.021 50.664 -17.578 1.00 13.72 ? 980 HIS A O 1 ATOM 7717 C CB . HIS A 1 980 ? 47.186 51.406 -14.712 1.00 10.49 ? 980 HIS A CB 1 ATOM 7718 C CG . HIS A 1 980 ? 45.709 51.341 -14.906 1.00 11.31 ? 980 HIS A CG 1 ATOM 7719 N ND1 . HIS A 1 980 ? 44.932 50.441 -14.213 1.00 12.21 ? 980 HIS A ND1 1 ATOM 7720 C CD2 . HIS A 1 980 ? 44.880 51.940 -15.797 1.00 11.55 ? 980 HIS A CD2 1 ATOM 7721 C CE1 . HIS A 1 980 ? 43.685 50.486 -14.671 1.00 12.36 ? 980 HIS A CE1 1 ATOM 7722 N NE2 . HIS A 1 980 ? 43.624 51.392 -15.631 1.00 12.69 ? 980 HIS A NE2 1 ATOM 7723 N N . ARG A 1 981 ? 46.698 48.930 -16.961 1.00 10.05 ? 981 ARG A N 1 ATOM 7724 C CA . ARG A 1 981 ? 46.211 48.770 -18.292 1.00 11.38 ? 981 ARG A CA 1 ATOM 7725 C C . ARG A 1 981 ? 44.719 48.923 -18.254 1.00 10.76 ? 981 ARG A C 1 ATOM 7726 O O . ARG A 1 981 ? 44.044 48.269 -17.445 1.00 10.01 ? 981 ARG A O 1 ATOM 7727 C CB . ARG A 1 981 ? 46.574 47.411 -18.899 1.00 10.77 ? 981 ARG A CB 1 ATOM 7728 C CG . ARG A 1 981 ? 46.202 47.391 -20.419 1.00 12.60 ? 981 ARG A CG 1 ATOM 7729 C CD . ARG A 1 981 ? 46.254 45.991 -21.066 1.00 17.61 ? 981 ARG A CD 1 ATOM 7730 N NE . ARG A 1 981 ? 47.510 45.331 -20.840 1.00 21.66 ? 981 ARG A NE 1 ATOM 7731 C CZ . ARG A 1 981 ? 48.519 45.310 -21.702 1.00 23.17 ? 981 ARG A CZ 1 ATOM 7732 N NH1 . ARG A 1 981 ? 48.420 45.924 -22.877 1.00 23.38 ? 981 ARG A NH1 1 ATOM 7733 N NH2 . ARG A 1 981 ? 49.629 44.653 -21.382 1.00 24.28 ? 981 ARG A NH2 1 ATOM 7734 N N . THR A 1 982 ? 44.189 49.801 -19.103 1.00 9.56 ? 982 THR A N 1 ATOM 7735 C CA . THR A 1 982 ? 42.758 50.008 -19.186 1.00 9.74 ? 982 THR A CA 1 ATOM 7736 C C . THR A 1 982 ? 42.259 49.006 -20.205 1.00 12.24 ? 982 THR A C 1 ATOM 7737 O O . THR A 1 982 ? 42.963 48.102 -20.595 1.00 12.87 ? 982 THR A O 1 ATOM 7738 C CB . THR A 1 982 ? 42.455 51.496 -19.590 1.00 9.87 ? 982 THR A CB 1 ATOM 7739 O OG1 . THR A 1 982 ? 41.055 51.730 -19.448 1.00 9.84 ? 982 THR A OG1 1 ATOM 7740 C CG2 . THR A 1 982 ? 42.951 51.813 -21.025 1.00 12.28 ? 982 THR A CG2 1 ATOM 7741 N N . ASN A 1 983 ? 40.991 49.084 -20.526 1.00 10.68 ? 983 ASN A N 1 ATOM 7742 C CA . ASN A 1 983 ? 40.427 48.212 -21.526 1.00 10.78 ? 983 ASN A CA 1 ATOM 7743 C C . ASN A 1 983 ? 39.745 49.102 -22.539 1.00 9.40 ? 983 ASN A C 1 ATOM 7744 O O . ASN A 1 983 ? 38.808 49.840 -22.226 1.00 10.76 ? 983 ASN A O 1 ATOM 7745 C CB . ASN A 1 983 ? 39.412 47.195 -20.968 1.00 10.61 ? 983 ASN A CB 1 ATOM 7746 C CG . ASN A 1 983 ? 38.952 46.217 -22.016 1.00 11.45 ? 983 ASN A CG 1 ATOM 7747 O OD1 . ASN A 1 983 ? 39.696 45.341 -22.438 1.00 11.73 ? 983 ASN A OD1 1 ATOM 7748 N ND2 . ASN A 1 983 ? 37.753 46.448 -22.519 1.00 10.36 ? 983 ASN A ND2 1 ATOM 7749 N N . LEU A 1 984 ? 40.178 48.963 -23.793 1.00 10.55 ? 984 LEU A N 1 ATOM 7750 C CA . LEU A 1 984 ? 39.628 49.792 -24.870 1.00 11.62 ? 984 LEU A CA 1 ATOM 7751 C C . LEU A 1 984 ? 38.769 48.988 -25.827 1.00 13.31 ? 984 LEU A C 1 ATOM 7752 O O . LEU A 1 984 ? 39.122 47.852 -26.148 1.00 15.87 ? 984 LEU A O 1 ATOM 7753 C CB . LEU A 1 984 ? 40.781 50.366 -25.668 1.00 12.22 ? 984 LEU A CB 1 ATOM 7754 C CG . LEU A 1 984 ? 41.708 51.246 -24.865 1.00 11.63 ? 984 LEU A CG 1 ATOM 7755 C CD1 . LEU A 1 984 ? 42.882 51.651 -25.760 1.00 13.01 ? 984 LEU A CD1 1 ATOM 7756 C CD2 . LEU A 1 984 ? 40.956 52.434 -24.286 1.00 11.61 ? 984 LEU A CD2 1 ATOM 7757 N N . MET A 1 985 ? 37.690 49.565 -26.345 1.00 15.35 ? 985 MET A N 1 ATOM 7758 C CA . MET A 1 985 ? 36.832 48.820 -27.266 1.00 17.99 ? 985 MET A CA 1 ATOM 7759 C C . MET A 1 985 ? 37.496 48.427 -28.574 1.00 20.73 ? 985 MET A C 1 ATOM 7760 O O . MET A 1 985 ? 38.269 49.188 -29.189 1.00 19.87 ? 985 MET A O 1 ATOM 7761 C CB . MET A 1 985 ? 35.570 49.594 -27.581 1.00 17.99 ? 985 MET A CB 1 ATOM 7762 C CG . MET A 1 985 ? 34.623 49.644 -26.419 1.00 20.04 ? 985 MET A CG 1 ATOM 7763 S SD . MET A 1 985 ? 32.917 49.587 -26.929 1.00 22.56 ? 985 MET A SD 1 ATOM 7764 C CE . MET A 1 985 ? 32.806 51.157 -27.684 1.00 24.59 ? 985 MET A CE 1 ATOM 7765 N N . GLN A 1 986 ? 37.176 47.219 -29.015 1.00 23.06 ? 986 GLN A N 1 ATOM 7766 C CA . GLN A 1 986 ? 37.735 46.749 -30.272 1.00 23.63 ? 986 GLN A CA 1 ATOM 7767 C C . GLN A 1 986 ? 36.708 47.113 -31.314 1.00 23.83 ? 986 GLN A C 1 ATOM 7768 O O . GLN A 1 986 ? 35.602 46.541 -31.275 1.00 21.55 ? 986 GLN A O 1 ATOM 7769 C CB . GLN A 1 986 ? 37.961 45.247 -30.218 1.00 26.94 ? 986 GLN A CB 1 ATOM 7770 C CG . GLN A 1 986 ? 39.103 44.893 -29.285 1.00 32.14 ? 986 GLN A CG 1 ATOM 7771 C CD . GLN A 1 986 ? 39.653 43.517 -29.535 1.00 35.11 ? 986 GLN A CD 1 ATOM 7772 O OE1 . GLN A 1 986 ? 39.114 42.491 -29.038 1.00 38.14 ? 986 GLN A OE1 1 ATOM 7773 N NE2 . GLN A 1 986 ? 40.727 43.458 -30.342 1.00 36.81 ? 986 GLN A NE2 1 ATOM 7774 N N . CYS A 1 987 ? 37.070 48.061 -32.202 1.00 22.63 ? 987 CYS A N 1 ATOM 7775 C CA . CYS A 1 987 ? 36.172 48.549 -33.248 1.00 25.05 ? 987 CYS A CA 1 ATOM 7776 C C . CYS A 1 987 ? 36.680 48.405 -34.683 1.00 28.38 ? 987 CYS A C 1 ATOM 7777 O O . CYS A 1 987 ? 36.313 49.215 -35.535 1.00 28.96 ? 987 CYS A O 1 ATOM 7778 C CB . CYS A 1 987 ? 35.854 50.015 -33.010 1.00 22.45 ? 987 CYS A CB 1 ATOM 7779 S SG . CYS A 1 987 ? 35.259 50.471 -31.325 1.00 21.03 ? 987 CYS A SG 1 ATOM 7780 N N . GLY A 1 988 ? 37.524 47.412 -34.943 1.00 30.32 ? 988 GLY A N 1 ATOM 7781 C CA . GLY A 1 988 ? 38.005 47.216 -36.299 1.00 34.92 ? 988 GLY A CA 1 ATOM 7782 C C . GLY A 1 988 ? 39.272 47.919 -36.746 1.00 38.00 ? 988 GLY A C 1 ATOM 7783 O O . GLY A 1 988 ? 39.595 47.909 -37.941 1.00 38.17 ? 988 GLY A O 1 ATOM 7784 N N . THR A 1 989 ? 39.989 48.538 -35.822 1.00 40.26 ? 989 THR A N 1 ATOM 7785 C CA . THR A 1 989 ? 41.235 49.214 -36.161 1.00 43.48 ? 989 THR A CA 1 ATOM 7786 C C . THR A 1 989 ? 42.361 48.232 -35.872 1.00 46.45 ? 989 THR A C 1 ATOM 7787 O O . THR A 1 989 ? 42.537 47.820 -34.725 1.00 46.33 ? 989 THR A O 1 ATOM 7788 C CB . THR A 1 989 ? 41.440 50.449 -35.302 1.00 42.83 ? 989 THR A CB 1 ATOM 7789 O OG1 . THR A 1 989 ? 40.253 51.248 -35.324 1.00 43.38 ? 989 THR A OG1 1 ATOM 7790 C CG2 . THR A 1 989 ? 42.586 51.267 -35.824 1.00 43.83 ? 989 THR A CG2 1 ATOM 7791 N N . PRO A 1 990 ? 43.127 47.830 -36.907 1.00 49.66 ? 990 PRO A N 1 ATOM 7792 C CA . PRO A 1 990 ? 44.246 46.887 -36.772 1.00 52.60 ? 990 PRO A CA 1 ATOM 7793 C C . PRO A 1 990 ? 45.243 47.183 -35.635 1.00 55.69 ? 990 PRO A C 1 ATOM 7794 O O . PRO A 1 990 ? 45.511 46.307 -34.800 1.00 56.46 ? 990 PRO A O 1 ATOM 7795 C CB . PRO A 1 990 ? 44.906 46.940 -38.149 1.00 52.10 ? 990 PRO A CB 1 ATOM 7796 C CG . PRO A 1 990 ? 43.758 47.161 -39.063 1.00 51.01 ? 990 PRO A CG 1 ATOM 7797 C CD . PRO A 1 990 ? 42.943 48.212 -38.323 1.00 50.45 ? 990 PRO A CD 1 ATOM 7798 N N . GLU A 1 991 ? 45.795 48.398 -35.602 1.00 58.67 ? 991 GLU A N 1 ATOM 7799 C CA . GLU A 1 991 ? 46.770 48.797 -34.568 1.00 62.00 ? 991 GLU A CA 1 ATOM 7800 C C . GLU A 1 991 ? 47.571 47.622 -33.943 1.00 62.76 ? 991 GLU A C 1 ATOM 7801 O O . GLU A 1 991 ? 47.102 46.973 -32.999 1.00 63.10 ? 991 GLU A O 1 ATOM 7802 C CB . GLU A 1 991 ? 46.036 49.591 -33.467 1.00 63.54 ? 991 GLU A CB 1 ATOM 7803 C CG . GLU A 1 991 ? 45.273 50.817 -34.011 1.00 65.82 ? 991 GLU A CG 1 ATOM 7804 C CD . GLU A 1 991 ? 44.367 51.504 -32.980 1.00 67.20 ? 991 GLU A CD 1 ATOM 7805 O OE1 . GLU A 1 991 ? 43.406 50.864 -32.488 1.00 67.60 ? 991 GLU A OE1 1 ATOM 7806 O OE2 . GLU A 1 991 ? 44.612 52.697 -32.672 1.00 68.04 ? 991 GLU A OE2 1 ATOM 7807 N N . GLU A 1 992 ? 48.774 47.350 -34.454 1.00 63.47 ? 992 GLU A N 1 ATOM 7808 C CA . GLU A 1 992 ? 49.565 46.233 -33.914 1.00 64.11 ? 992 GLU A CA 1 ATOM 7809 C C . GLU A 1 992 ? 51.093 46.403 -33.831 1.00 62.97 ? 992 GLU A C 1 ATOM 7810 O O . GLU A 1 992 ? 51.807 45.400 -33.692 1.00 63.56 ? 992 GLU A O 1 ATOM 7811 C CB . GLU A 1 992 ? 49.286 44.942 -34.719 1.00 66.35 ? 992 GLU A CB 1 ATOM 7812 C CG . GLU A 1 992 ? 47.885 44.827 -35.352 1.00 68.79 ? 992 GLU A CG 1 ATOM 7813 C CD . GLU A 1 992 ? 47.567 43.429 -35.910 1.00 70.31 ? 992 GLU A CD 1 ATOM 7814 O OE1 . GLU A 1 992 ? 48.332 42.472 -35.641 1.00 71.05 ? 992 GLU A OE1 1 ATOM 7815 O OE2 . GLU A 1 992 ? 46.537 43.287 -36.611 1.00 70.94 ? 992 GLU A OE2 1 ATOM 7816 N N . HIS A 1 993 ? 51.613 47.628 -33.897 1.00 61.00 ? 993 HIS A N 1 ATOM 7817 C CA . HIS A 1 993 ? 53.078 47.798 -33.860 1.00 58.31 ? 993 HIS A CA 1 ATOM 7818 C C . HIS A 1 993 ? 53.674 48.470 -32.617 1.00 54.58 ? 993 HIS A C 1 ATOM 7819 O O . HIS A 1 993 ? 54.058 49.644 -32.671 1.00 54.27 ? 993 HIS A O 1 ATOM 7820 C CB . HIS A 1 993 ? 53.553 48.554 -35.116 1.00 61.05 ? 993 HIS A CB 1 ATOM 7821 C CG . HIS A 1 993 ? 53.309 47.812 -36.400 1.00 64.26 ? 993 HIS A CG 1 ATOM 7822 N ND1 . HIS A 1 993 ? 53.863 46.575 -36.666 1.00 65.38 ? 993 HIS A ND1 1 ATOM 7823 C CD2 . HIS A 1 993 ? 52.547 48.120 -37.480 1.00 65.03 ? 993 HIS A CD2 1 ATOM 7824 C CE1 . HIS A 1 993 ? 53.452 46.153 -37.850 1.00 65.92 ? 993 HIS A CE1 1 ATOM 7825 N NE2 . HIS A 1 993 ? 52.652 47.072 -38.364 1.00 65.67 ? 993 HIS A NE2 1 ATOM 7826 N N . THR A 1 994 ? 53.775 47.726 -31.510 1.00 49.18 ? 994 THR A N 1 ATOM 7827 C CA . THR A 1 994 ? 54.343 48.277 -30.270 1.00 43.30 ? 994 THR A CA 1 ATOM 7828 C C . THR A 1 994 ? 55.341 47.346 -29.586 1.00 39.88 ? 994 THR A C 1 ATOM 7829 O O . THR A 1 994 ? 55.403 46.162 -29.890 1.00 39.41 ? 994 THR A O 1 ATOM 7830 C CB . THR A 1 994 ? 53.241 48.620 -29.243 1.00 42.78 ? 994 THR A CB 1 ATOM 7831 O OG1 . THR A 1 994 ? 52.497 47.437 -28.926 1.00 41.46 ? 994 THR A OG1 1 ATOM 7832 C CG2 . THR A 1 994 ? 52.295 49.656 -29.816 1.00 42.00 ? 994 THR A CG2 1 ATOM 7833 N N . GLN A 1 995 ? 56.105 47.901 -28.648 1.00 34.62 ? 995 GLN A N 1 ATOM 7834 C CA . GLN A 1 995 ? 57.112 47.152 -27.902 1.00 30.23 ? 995 GLN A CA 1 ATOM 7835 C C . GLN A 1 995 ? 56.625 46.728 -26.512 1.00 26.73 ? 995 GLN A C 1 ATOM 7836 O O . GLN A 1 995 ? 55.868 47.440 -25.856 1.00 24.81 ? 995 GLN A O 1 ATOM 7837 C CB . GLN A 1 995 ? 58.368 48.009 -27.718 1.00 30.26 ? 995 GLN A CB 1 ATOM 7838 C CG . GLN A 1 995 ? 59.103 48.316 -29.025 1.00 31.60 ? 995 GLN A CG 1 ATOM 7839 C CD . GLN A 1 995 ? 59.710 49.714 -29.077 1.00 32.31 ? 995 GLN A CD 1 ATOM 7840 O OE1 . GLN A 1 995 ? 59.008 50.725 -28.999 1.00 29.16 ? 995 GLN A OE1 1 ATOM 7841 N NE2 . GLN A 1 995 ? 61.032 49.773 -29.238 1.00 34.02 ? 995 GLN A NE2 1 ATOM 7842 N N . LYS A 1 996 ? 57.089 45.569 -26.086 1.00 23.58 ? 996 LYS A N 1 ATOM 7843 C CA . LYS A 1 996 ? 56.792 45.062 -24.745 1.00 22.93 ? 996 LYS A CA 1 ATOM 7844 C C . LYS A 1 996 ? 57.524 46.030 -23.800 1.00 20.72 ? 996 LYS A C 1 ATOM 7845 O O . LYS A 1 996 ? 58.679 46.411 -24.046 1.00 18.88 ? 996 LYS A O 1 ATOM 7846 C CB . LYS A 1 996 ? 57.348 43.623 -24.604 1.00 24.98 ? 996 LYS A CB 1 ATOM 7847 C CG . LYS A 1 996 ? 57.264 43.024 -23.218 1.00 28.56 ? 996 LYS A CG 1 ATOM 7848 C CD . LYS A 1 996 ? 57.885 41.573 -23.148 1.00 30.50 ? 996 LYS A CD 1 ATOM 7849 C CE . LYS A 1 996 ? 58.058 41.132 -21.681 1.00 32.36 ? 996 LYS A CE 1 ATOM 7850 N NZ . LYS A 1 996 ? 58.925 39.905 -21.533 1.00 34.59 ? 996 LYS A NZ 1 ATOM 7851 N N . LEU A 1 997 ? 56.848 46.438 -22.723 1.00 18.11 ? 997 LEU A N 1 ATOM 7852 C CA . LEU A 1 997 ? 57.455 47.351 -21.765 1.00 17.96 ? 997 LEU A CA 1 ATOM 7853 C C . LEU A 1 997 ? 57.770 46.511 -20.550 1.00 16.69 ? 997 LEU A C 1 ATOM 7854 O O . LEU A 1 997 ? 56.861 45.929 -19.989 1.00 15.88 ? 997 LEU A O 1 ATOM 7855 C CB . LEU A 1 997 ? 56.480 48.469 -21.334 1.00 18.32 ? 997 LEU A CB 1 ATOM 7856 C CG . LEU A 1 997 ? 56.997 49.393 -20.239 1.00 20.78 ? 997 LEU A CG 1 ATOM 7857 C CD1 . LEU A 1 997 ? 58.333 50.061 -20.550 1.00 18.59 ? 997 LEU A CD1 1 ATOM 7858 C CD2 . LEU A 1 997 ? 55.925 50.444 -20.021 1.00 21.53 ? 997 LEU A CD2 1 ATOM 7859 N N . ASP A 1 998 ? 59.044 46.451 -20.201 1.00 17.45 ? 998 ASP A N 1 ATOM 7860 C CA . ASP A 1 998 ? 59.532 45.748 -19.021 1.00 17.39 ? 998 ASP A CA 1 ATOM 7861 C C . ASP A 1 998 ? 60.110 46.866 -18.120 1.00 16.52 ? 998 ASP A C 1 ATOM 7862 O O . ASP A 1 998 ? 61.243 47.337 -18.302 1.00 17.25 ? 998 ASP A O 1 ATOM 7863 C CB . ASP A 1 998 ? 60.629 44.751 -19.405 1.00 18.14 ? 998 ASP A CB 1 ATOM 7864 C CG . ASP A 1 998 ? 61.411 44.277 -18.213 1.00 21.23 ? 998 ASP A CG 1 ATOM 7865 O OD1 . ASP A 1 998 ? 61.012 44.588 -17.078 1.00 19.04 ? 998 ASP A OD1 1 ATOM 7866 O OD2 . ASP A 1 998 ? 62.436 43.577 -18.399 1.00 21.42 ? 998 ASP A OD2 1 ATOM 7867 N N . VAL A 1 999 ? 59.325 47.306 -17.131 1.00 16.09 ? 999 VAL A N 1 ATOM 7868 C CA . VAL A 1 999 ? 59.831 48.401 -16.350 1.00 14.62 ? 999 VAL A CA 1 ATOM 7869 C C . VAL A 1 999 ? 61.111 48.146 -15.581 1.00 14.93 ? 999 VAL A C 1 ATOM 7870 O O . VAL A 1 999 ? 61.881 49.080 -15.372 1.00 16.02 ? 999 VAL A O 1 ATOM 7871 C CB . VAL A 1 999 ? 58.759 49.004 -15.404 1.00 13.84 ? 999 VAL A CB 1 ATOM 7872 C CG1 . VAL A 1 999 ? 57.622 49.545 -16.244 1.00 14.06 ? 999 VAL A CG1 1 ATOM 7873 C CG2 . VAL A 1 999 ? 58.307 47.981 -14.351 1.00 13.75 ? 999 VAL A CG2 1 ATOM 7874 N N . CYS A 1 1000 ? 61.357 46.884 -15.210 1.00 15.18 ? 1000 CYS A N 1 ATOM 7875 C CA . CYS A 1 1000 ? 62.558 46.572 -14.490 1.00 16.81 ? 1000 CYS A CA 1 ATOM 7876 C C . CYS A 1 1000 ? 63.869 46.809 -15.255 1.00 16.56 ? 1000 CYS A C 1 ATOM 7877 O O . CYS A 1 1000 ? 64.928 46.894 -14.646 1.00 17.62 ? 1000 CYS A O 1 ATOM 7878 C CB . CYS A 1 1000 ? 62.474 45.145 -13.928 1.00 18.31 ? 1000 CYS A CB 1 ATOM 7879 S SG . CYS A 1 1000 ? 61.525 45.148 -12.340 1.00 20.59 ? 1000 CYS A SG 1 ATOM 7880 N N . HIS A 1 1001 ? 63.800 46.890 -16.577 1.00 17.74 ? 1001 HIS A N 1 ATOM 7881 C CA . HIS A 1 1001 ? 65.027 47.176 -17.306 1.00 18.68 ? 1001 HIS A CA 1 ATOM 7882 C C . HIS A 1 1001 ? 65.101 48.660 -17.780 1.00 19.52 ? 1001 HIS A C 1 ATOM 7883 O O . HIS A 1 1001 ? 65.942 48.987 -18.597 1.00 21.22 ? 1001 HIS A O 1 ATOM 7884 C CB . HIS A 1 1001 ? 65.220 46.192 -18.477 1.00 18.67 ? 1001 HIS A CB 1 ATOM 7885 C CG . HIS A 1 1001 ? 65.767 44.856 -18.045 1.00 18.35 ? 1001 HIS A CG 1 ATOM 7886 N ND1 . HIS A 1 1001 ? 64.971 43.848 -17.545 1.00 18.29 ? 1001 HIS A ND1 1 ATOM 7887 C CD2 . HIS A 1 1001 ? 67.043 44.410 -17.950 1.00 18.35 ? 1001 HIS A CD2 1 ATOM 7888 C CE1 . HIS A 1 1001 ? 65.735 42.838 -17.155 1.00 19.43 ? 1001 HIS A CE1 1 ATOM 7889 N NE2 . HIS A 1 1001 ? 66.995 43.155 -17.385 1.00 18.65 ? 1001 HIS A NE2 1 ATOM 7890 N N . LEU A 1 1002 ? 64.256 49.570 -17.267 1.00 20.91 ? 1002 LEU A N 1 ATOM 7891 C CA . LEU A 1 1002 ? 64.311 50.984 -17.708 1.00 19.51 ? 1002 LEU A CA 1 ATOM 7892 C C . LEU A 1 1002 ? 65.579 51.634 -17.180 1.00 19.60 ? 1002 LEU A C 1 ATOM 7893 O O . LEU A 1 1002 ? 66.106 52.545 -17.791 1.00 20.94 ? 1002 LEU A O 1 ATOM 7894 C CB . LEU A 1 1002 ? 63.089 51.784 -17.220 1.00 19.28 ? 1002 LEU A CB 1 ATOM 7895 C CG . LEU A 1 1002 ? 61.835 51.538 -18.063 1.00 16.60 ? 1002 LEU A CG 1 ATOM 7896 C CD1 . LEU A 1 1002 ? 60.629 52.246 -17.435 1.00 18.15 ? 1002 LEU A CD1 1 ATOM 7897 C CD2 . LEU A 1 1002 ? 62.076 52.064 -19.473 1.00 18.72 ? 1002 LEU A CD2 1 ATOM 7898 N N . LEU A 1 1003 ? 66.083 51.163 -16.044 1.00 19.77 ? 1003 LEU A N 1 ATOM 7899 C CA . LEU A 1 1003 ? 67.320 51.681 -15.498 1.00 20.48 ? 1003 LEU A CA 1 ATOM 7900 C C . LEU A 1 1003 ? 68.375 50.568 -15.636 1.00 21.60 ? 1003 LEU A C 1 ATOM 7901 O O . LEU A 1 1003 ? 68.038 49.381 -15.629 1.00 21.25 ? 1003 LEU A O 1 ATOM 7902 C CB . LEU A 1 1003 ? 67.125 52.092 -14.048 1.00 20.90 ? 1003 LEU A CB 1 ATOM 7903 C CG . LEU A 1 1003 ? 66.470 53.489 -13.933 1.00 24.08 ? 1003 LEU A CG 1 ATOM 7904 C CD1 . LEU A 1 1003 ? 65.965 53.734 -12.534 1.00 23.88 ? 1003 LEU A CD1 1 ATOM 7905 C CD2 . LEU A 1 1003 ? 67.529 54.554 -14.345 1.00 21.83 ? 1003 LEU A CD2 1 ATOM 7906 N N . PRO A 1 1004 ? 69.656 50.948 -15.830 1.00 22.61 ? 1004 PRO A N 1 ATOM 7907 C CA . PRO A 1 1004 ? 70.737 49.975 -15.983 1.00 22.11 ? 1004 PRO A CA 1 ATOM 7908 C C . PRO A 1 1004 ? 71.142 49.273 -14.663 1.00 22.25 ? 1004 PRO A C 1 ATOM 7909 O O . PRO A 1 1004 ? 70.731 49.650 -13.577 1.00 21.27 ? 1004 PRO A O 1 ATOM 7910 C CB . PRO A 1 1004 ? 71.860 50.835 -16.584 1.00 22.19 ? 1004 PRO A CB 1 ATOM 7911 C CG . PRO A 1 1004 ? 71.714 52.116 -15.832 1.00 23.82 ? 1004 PRO A CG 1 ATOM 7912 C CD . PRO A 1 1004 ? 70.183 52.334 -15.838 1.00 22.29 ? 1004 PRO A CD 1 ATOM 7913 N N . ASN A 1 1005 ? 71.964 48.239 -14.797 1.00 21.29 ? 1005 ASN A N 1 ATOM 7914 C CA . ASN A 1 1005 ? 72.459 47.448 -13.675 1.00 21.20 ? 1005 ASN A CA 1 ATOM 7915 C C . ASN A 1 1005 ? 71.366 46.887 -12.745 1.00 20.40 ? 1005 ASN A C 1 ATOM 7916 O O . ASN A 1 1005 ? 71.502 46.945 -11.540 1.00 20.49 ? 1005 ASN A O 1 ATOM 7917 C CB . ASN A 1 1005 ? 73.484 48.250 -12.859 1.00 21.63 ? 1005 ASN A CB 1 ATOM 7918 C CG . ASN A 1 1005 ? 74.487 48.990 -13.756 1.00 25.86 ? 1005 ASN A CG 1 ATOM 7919 O OD1 . ASN A 1 1005 ? 74.310 50.180 -14.058 1.00 28.67 ? 1005 ASN A OD1 1 ATOM 7920 N ND2 . ASN A 1 1005 ? 75.516 48.298 -14.187 1.00 24.59 ? 1005 ASN A ND2 1 ATOM 7921 N N . VAL A 1 1006 ? 70.307 46.332 -13.324 1.00 20.68 ? 1006 VAL A N 1 ATOM 7922 C CA . VAL A 1 1006 ? 69.251 45.790 -12.489 1.00 21.76 ? 1006 VAL A CA 1 ATOM 7923 C C . VAL A 1 1006 ? 69.797 44.470 -11.891 1.00 22.32 ? 1006 VAL A C 1 ATOM 7924 O O . VAL A 1 1006 ? 70.367 43.655 -12.614 1.00 24.03 ? 1006 VAL A O 1 ATOM 7925 C CB . VAL A 1 1006 ? 67.928 45.536 -13.293 1.00 22.80 ? 1006 VAL A CB 1 ATOM 7926 C CG1 . VAL A 1 1006 ? 68.107 44.513 -14.375 1.00 23.61 ? 1006 VAL A CG1 1 ATOM 7927 C CG2 . VAL A 1 1006 ? 66.848 45.023 -12.338 1.00 23.15 ? 1006 VAL A CG2 1 ATOM 7928 N N . ALA A 1 1007 ? 69.603 44.307 -10.587 1.00 20.00 ? 1007 ALA A N 1 ATOM 7929 C CA . ALA A 1 1007 ? 70.039 43.142 -9.820 1.00 20.74 ? 1007 ALA A CA 1 ATOM 7930 C C . ALA A 1 1007 ? 68.830 42.333 -9.367 1.00 22.25 ? 1007 ALA A C 1 ATOM 7931 O O . ALA A 1 1007 ? 68.959 41.174 -8.952 1.00 22.66 ? 1007 ALA A O 1 ATOM 7932 C CB . ALA A 1 1007 ? 70.821 43.617 -8.594 1.00 20.82 ? 1007 ALA A CB 1 ATOM 7933 N N . ARG A 1 1008 ? 67.643 42.928 -9.419 1.00 21.78 ? 1008 ARG A N 1 ATOM 7934 C CA . ARG A 1 1008 ? 66.467 42.194 -8.995 1.00 19.74 ? 1008 ARG A CA 1 ATOM 7935 C C . ARG A 1 1008 ? 65.224 42.933 -9.416 1.00 17.84 ? 1008 ARG A C 1 ATOM 7936 O O . ARG A 1 1008 ? 65.234 44.152 -9.468 1.00 16.66 ? 1008 ARG A O 1 ATOM 7937 C CB . ARG A 1 1008 ? 66.431 42.110 -7.477 1.00 21.82 ? 1008 ARG A CB 1 ATOM 7938 C CG . ARG A 1 1008 ? 65.389 41.218 -6.945 1.00 25.24 ? 1008 ARG A CG 1 ATOM 7939 C CD . ARG A 1 1008 ? 65.703 40.898 -5.487 1.00 30.16 ? 1008 ARG A CD 1 ATOM 7940 N NE . ARG A 1 1008 ? 64.622 40.108 -4.909 1.00 34.93 ? 1008 ARG A NE 1 ATOM 7941 C CZ . ARG A 1 1008 ? 64.787 38.925 -4.321 1.00 37.49 ? 1008 ARG A CZ 1 ATOM 7942 N NH1 . ARG A 1 1008 ? 66.010 38.390 -4.229 1.00 38.30 ? 1008 ARG A NH1 1 ATOM 7943 N NH2 . ARG A 1 1008 ? 63.724 38.274 -3.847 1.00 38.10 ? 1008 ARG A NH2 1 ATOM 7944 N N . CYS A 1 1009 ? 64.154 42.177 -9.601 1.00 15.26 ? 1009 CYS A N 1 ATOM 7945 C CA . CYS A 1 1009 ? 62.864 42.748 -9.958 1.00 16.56 ? 1009 CYS A CA 1 ATOM 7946 C C . CYS A 1 1009 ? 61.827 41.997 -9.127 1.00 15.71 ? 1009 CYS A C 1 ATOM 7947 O O . CYS A 1 1009 ? 61.740 40.753 -9.205 1.00 14.51 ? 1009 CYS A O 1 ATOM 7948 C CB . CYS A 1 1009 ? 62.590 42.531 -11.440 1.00 16.16 ? 1009 CYS A CB 1 ATOM 7949 S SG . CYS A 1 1009 ? 61.016 43.200 -12.116 1.00 22.58 ? 1009 CYS A SG 1 ATOM 7950 N N . GLU A 1 1010 ? 61.015 42.745 -8.364 1.00 15.14 ? 1010 GLU A N 1 ATOM 7951 C CA . GLU A 1 1010 ? 59.967 42.188 -7.544 1.00 13.86 ? 1010 GLU A CA 1 ATOM 7952 C C . GLU A 1 1010 ? 58.596 42.775 -7.819 1.00 13.43 ? 1010 GLU A C 1 ATOM 7953 O O . GLU A 1 1010 ? 58.467 43.987 -8.026 1.00 12.86 ? 1010 GLU A O 1 ATOM 7954 C CB . GLU A 1 1010 ? 60.306 42.470 -6.106 1.00 14.79 ? 1010 GLU A CB 1 ATOM 7955 C CG . GLU A 1 1010 ? 61.540 41.640 -5.712 1.00 20.18 ? 1010 GLU A CG 1 ATOM 7956 C CD . GLU A 1 1010 ? 62.338 42.223 -4.583 1.00 24.44 ? 1010 GLU A CD 1 ATOM 7957 O OE1 . GLU A 1 1010 ? 62.608 43.443 -4.552 1.00 27.16 ? 1010 GLU A OE1 1 ATOM 7958 O OE2 . GLU A 1 1010 ? 62.738 41.404 -3.712 1.00 24.86 ? 1010 GLU A OE2 1 ATOM 7959 N N . ARG A 1 1011 ? 57.588 41.917 -7.835 1.00 12.86 ? 1011 ARG A N 1 ATOM 7960 C CA . ARG A 1 1011 ? 56.225 42.446 -7.896 1.00 11.21 ? 1011 ARG A CA 1 ATOM 7961 C C . ARG A 1 1011 ? 55.874 42.744 -6.407 1.00 12.16 ? 1011 ARG A C 1 ATOM 7962 O O . ARG A 1 1011 ? 56.158 41.948 -5.506 1.00 12.69 ? 1011 ARG A O 1 ATOM 7963 C CB . ARG A 1 1011 ? 55.240 41.463 -8.480 1.00 11.44 ? 1011 ARG A CB 1 ATOM 7964 C CG . ARG A 1 1011 ? 53.874 42.151 -8.600 1.00 13.74 ? 1011 ARG A CG 1 ATOM 7965 C CD . ARG A 1 1011 ? 52.903 41.351 -9.389 1.00 17.87 ? 1011 ARG A CD 1 ATOM 7966 N NE . ARG A 1 1011 ? 52.575 40.114 -8.682 1.00 19.20 ? 1011 ARG A NE 1 ATOM 7967 C CZ . ARG A 1 1011 ? 51.680 40.048 -7.686 1.00 22.84 ? 1011 ARG A CZ 1 ATOM 7968 N NH1 . ARG A 1 1011 ? 51.048 41.163 -7.296 1.00 24.97 ? 1011 ARG A NH1 1 ATOM 7969 N NH2 . ARG A 1 1011 ? 51.372 38.869 -7.104 1.00 26.37 ? 1011 ARG A NH2 1 ATOM 7970 N N . THR A 1 1012 ? 55.252 43.896 -6.168 1.00 10.49 ? 1012 THR A N 1 ATOM 7971 C CA . THR A 1 1012 ? 54.885 44.350 -4.850 1.00 10.08 ? 1012 THR A CA 1 ATOM 7972 C C . THR A 1 1012 ? 53.435 44.805 -4.769 1.00 8.14 ? 1012 THR A C 1 ATOM 7973 O O . THR A 1 1012 ? 52.725 44.915 -5.782 1.00 9.41 ? 1012 THR A O 1 ATOM 7974 C CB . THR A 1 1012 ? 55.755 45.567 -4.398 1.00 8.50 ? 1012 THR A CB 1 ATOM 7975 O OG1 . THR A 1 1012 ? 55.480 46.700 -5.246 1.00 11.36 ? 1012 THR A OG1 1 ATOM 7976 C CG2 . THR A 1 1012 ? 57.261 45.261 -4.457 1.00 10.71 ? 1012 THR A CG2 1 ATOM 7977 N N . THR A 1 1013 ? 53.000 45.059 -3.535 1.00 8.47 ? 1013 THR A N 1 ATOM 7978 C CA . THR A 1 1013 ? 51.688 45.665 -3.312 1.00 9.02 ? 1013 THR A CA 1 ATOM 7979 C C . THR A 1 1013 ? 51.802 47.062 -3.938 1.00 9.31 ? 1013 THR A C 1 ATOM 7980 O O . THR A 1 1013 ? 52.905 47.577 -4.154 1.00 8.97 ? 1013 THR A O 1 ATOM 7981 C CB . THR A 1 1013 ? 51.403 45.802 -1.802 1.00 9.35 ? 1013 THR A CB 1 ATOM 7982 O OG1 . THR A 1 1013 ? 52.606 46.224 -1.148 1.00 8.81 ? 1013 THR A OG1 1 ATOM 7983 C CG2 . THR A 1 1013 ? 50.904 44.451 -1.204 1.00 9.83 ? 1013 THR A CG2 1 ATOM 7984 N N . LEU A 1 1014 ? 50.674 47.691 -4.171 1.00 7.92 ? 1014 LEU A N 1 ATOM 7985 C CA . LEU A 1 1014 ? 50.676 48.995 -4.877 1.00 7.55 ? 1014 LEU A CA 1 ATOM 7986 C C . LEU A 1 1014 ? 51.327 50.147 -4.145 1.00 7.77 ? 1014 LEU A C 1 ATOM 7987 O O . LEU A 1 1014 ? 51.697 51.136 -4.740 1.00 8.08 ? 1014 LEU A O 1 ATOM 7988 C CB . LEU A 1 1014 ? 49.225 49.416 -5.303 1.00 7.98 ? 1014 LEU A CB 1 ATOM 7989 C CG . LEU A 1 1014 ? 48.454 48.471 -6.193 1.00 8.82 ? 1014 LEU A CG 1 ATOM 7990 C CD1 . LEU A 1 1014 ? 47.161 49.146 -6.516 1.00 9.68 ? 1014 LEU A CD1 1 ATOM 7991 C CD2 . LEU A 1 1014 ? 49.243 48.112 -7.535 1.00 8.84 ? 1014 LEU A CD2 1 ATOM 7992 N N . THR A 1 1015 ? 51.523 49.997 -2.836 1.00 5.95 ? 1015 THR A N 1 ATOM 7993 C CA . THR A 1 1015 ? 52.147 50.956 -1.983 1.00 6.91 ? 1015 THR A CA 1 ATOM 7994 C C . THR A 1 1015 ? 53.664 50.728 -1.919 1.00 7.24 ? 1015 THR A C 1 ATOM 7995 O O . THR A 1 1015 ? 54.398 51.477 -1.260 1.00 8.45 ? 1015 THR A O 1 ATOM 7996 C CB . THR A 1 1015 ? 51.649 50.815 -0.555 1.00 8.84 ? 1015 THR A CB 1 ATOM 7997 O OG1 . THR A 1 1015 ? 51.819 49.434 -0.149 1.00 7.53 ? 1015 THR A OG1 1 ATOM 7998 C CG2 . THR A 1 1015 ? 50.149 51.187 -0.465 1.00 9.25 ? 1015 THR A CG2 1 ATOM 7999 N N . PHE A 1 1016 ? 54.123 49.651 -2.575 1.00 8.78 ? 1016 PHE A N 1 ATOM 8000 C CA . PHE A 1 1016 ? 55.537 49.179 -2.648 1.00 8.47 ? 1016 PHE A CA 1 ATOM 8001 C C . PHE A 1 1016 ? 56.012 48.659 -1.284 1.00 9.82 ? 1016 PHE A C 1 ATOM 8002 O O . PHE A 1 1016 ? 57.212 48.443 -1.155 1.00 11.53 ? 1016 PHE A O 1 ATOM 8003 C CB . PHE A 1 1016 ? 56.501 50.307 -3.068 1.00 9.61 ? 1016 PHE A CB 1 ATOM 8004 C CG . PHE A 1 1016 ? 56.137 50.956 -4.397 1.00 8.66 ? 1016 PHE A CG 1 ATOM 8005 C CD1 . PHE A 1 1016 ? 55.994 50.215 -5.581 1.00 9.07 ? 1016 PHE A CD1 1 ATOM 8006 C CD2 . PHE A 1 1016 ? 55.984 52.339 -4.461 1.00 8.12 ? 1016 PHE A CD2 1 ATOM 8007 C CE1 . PHE A 1 1016 ? 55.711 50.934 -6.815 1.00 8.02 ? 1016 PHE A CE1 1 ATOM 8008 C CE2 . PHE A 1 1016 ? 55.708 53.006 -5.659 1.00 9.62 ? 1016 PHE A CE2 1 ATOM 8009 C CZ . PHE A 1 1016 ? 55.582 52.347 -6.785 1.00 9.87 ? 1016 PHE A CZ 1 ATOM 8010 N N . LEU A 1 1017 ? 55.117 48.397 -0.334 1.00 9.35 ? 1017 LEU A N 1 ATOM 8011 C CA . LEU A 1 1017 ? 55.574 48.022 1.019 1.00 9.11 ? 1017 LEU A CA 1 ATOM 8012 C C . LEU A 1 1017 ? 55.766 46.547 1.302 1.00 10.89 ? 1017 LEU A C 1 ATOM 8013 O O . LEU A 1 1017 ? 56.383 46.204 2.336 1.00 12.82 ? 1017 LEU A O 1 ATOM 8014 C CB . LEU A 1 1017 ? 54.642 48.632 2.053 1.00 8.75 ? 1017 LEU A CB 1 ATOM 8015 C CG . LEU A 1 1017 ? 54.693 50.154 1.961 1.00 6.72 ? 1017 LEU A CG 1 ATOM 8016 C CD1 . LEU A 1 1017 ? 53.550 50.627 2.901 1.00 9.87 ? 1017 LEU A CD1 1 ATOM 8017 C CD2 . LEU A 1 1017 ? 56.048 50.721 2.351 1.00 10.61 ? 1017 LEU A CD2 1 ATOM 8018 N N . GLN A 1 1018 ? 55.290 45.651 0.452 1.00 11.09 ? 1018 GLN A N 1 ATOM 8019 C CA . GLN A 1 1018 ? 55.458 44.220 0.635 1.00 12.84 ? 1018 GLN A CA 1 ATOM 8020 C C . GLN A 1 1018 ? 55.822 43.590 -0.700 1.00 13.47 ? 1018 GLN A C 1 ATOM 8021 O O . GLN A 1 1018 ? 55.160 43.879 -1.713 1.00 11.03 ? 1018 GLN A O 1 ATOM 8022 C CB . GLN A 1 1018 ? 54.148 43.587 1.086 1.00 14.13 ? 1018 GLN A CB 1 ATOM 8023 C CG . GLN A 1 1018 ? 54.302 42.059 1.301 1.00 19.31 ? 1018 GLN A CG 1 ATOM 8024 C CD . GLN A 1 1018 ? 53.096 41.468 1.969 1.00 24.15 ? 1018 GLN A CD 1 ATOM 8025 O OE1 . GLN A 1 1018 ? 51.966 41.875 1.696 1.00 24.51 ? 1018 GLN A OE1 1 ATOM 8026 N NE2 . GLN A 1 1018 ? 53.318 40.475 2.844 1.00 26.89 ? 1018 GLN A NE2 1 ATOM 8027 N N . ASN A 1 1019 ? 56.819 42.687 -0.711 1.00 13.65 ? 1019 ASN A N 1 ATOM 8028 C CA . ASN A 1 1019 ? 57.215 42.006 -1.947 1.00 13.62 ? 1019 ASN A CA 1 ATOM 8029 C C . ASN A 1 1019 ? 56.311 40.786 -2.059 1.00 15.60 ? 1019 ASN A C 1 ATOM 8030 O O . ASN A 1 1019 ? 56.122 40.049 -1.067 1.00 18.17 ? 1019 ASN A O 1 ATOM 8031 C CB . ASN A 1 1019 ? 58.690 41.557 -1.917 1.00 16.41 ? 1019 ASN A CB 1 ATOM 8032 C CG . ASN A 1 1019 ? 59.672 42.714 -1.744 1.00 17.46 ? 1019 ASN A CG 1 ATOM 8033 O OD1 . ASN A 1 1019 ? 59.507 43.802 -2.312 1.00 18.64 ? 1019 ASN A OD1 1 ATOM 8034 N ND2 . ASN A 1 1019 ? 60.733 42.461 -0.985 1.00 20.48 ? 1019 ASN A ND2 1 ATOM 8035 N N . LEU A 1 1020 ? 55.710 40.594 -3.218 1.00 14.71 ? 1020 LEU A N 1 ATOM 8036 C CA . LEU A 1 1020 ? 54.779 39.513 -3.455 1.00 16.14 ? 1020 LEU A CA 1 ATOM 8037 C C . LEU A 1 1020 ? 55.356 38.426 -4.371 1.00 17.25 ? 1020 LEU A C 1 ATOM 8038 O O . LEU A 1 1020 ? 54.890 37.274 -4.322 1.00 18.64 ? 1020 LEU A O 1 ATOM 8039 C CB . LEU A 1 1020 ? 53.488 40.057 -4.079 1.00 15.28 ? 1020 LEU A CB 1 ATOM 8040 C CG . LEU A 1 1020 ? 52.807 41.146 -3.266 1.00 15.81 ? 1020 LEU A CG 1 ATOM 8041 C CD1 . LEU A 1 1020 ? 51.648 41.719 -4.048 1.00 18.30 ? 1020 LEU A CD1 1 ATOM 8042 C CD2 . LEU A 1 1020 ? 52.314 40.535 -1.961 1.00 17.94 ? 1020 LEU A CD2 1 ATOM 8043 N N . GLU A 1 1021 ? 56.331 38.777 -5.223 1.00 18.10 ? 1021 GLU A N 1 ATOM 8044 C CA . GLU A 1 1021 ? 56.908 37.792 -6.149 1.00 20.08 ? 1021 GLU A CA 1 ATOM 8045 C C . GLU A 1 1021 ? 58.306 38.177 -6.626 1.00 20.75 ? 1021 GLU A C 1 ATOM 8046 O O . GLU A 1 1021 ? 58.538 39.306 -7.042 1.00 18.57 ? 1021 GLU A O 1 ATOM 8047 C CB . GLU A 1 1021 ? 55.974 37.669 -7.348 1.00 21.52 ? 1021 GLU A CB 1 ATOM 8048 C CG . GLU A 1 1021 ? 56.294 36.584 -8.346 1.00 26.16 ? 1021 GLU A CG 1 ATOM 8049 C CD . GLU A 1 1021 ? 55.427 36.742 -9.606 1.00 28.59 ? 1021 GLU A CD 1 ATOM 8050 O OE1 . GLU A 1 1021 ? 54.455 37.560 -9.604 1.00 27.78 ? 1021 GLU A OE1 1 ATOM 8051 O OE2 . GLU A 1 1021 ? 55.748 36.059 -10.602 1.00 31.25 ? 1021 GLU A OE2 1 ATOM 8052 N N . HIS A 1 1022 ? 59.262 37.267 -6.517 1.00 21.74 ? 1022 HIS A N 1 ATOM 8053 C CA . HIS A 1 1022 ? 60.616 37.518 -6.992 1.00 24.74 ? 1022 HIS A CA 1 ATOM 8054 C C . HIS A 1 1022 ? 60.513 37.162 -8.474 1.00 23.92 ? 1022 HIS A C 1 ATOM 8055 O O . HIS A 1 1022 ? 60.164 36.039 -8.805 1.00 24.55 ? 1022 HIS A O 1 ATOM 8056 C CB . HIS A 1 1022 ? 61.590 36.570 -6.296 1.00 27.79 ? 1022 HIS A CB 1 ATOM 8057 C CG . HIS A 1 1022 ? 63.017 36.960 -6.454 1.00 33.01 ? 1022 HIS A CG 1 ATOM 8058 N ND1 . HIS A 1 1022 ? 64.057 36.170 -6.006 1.00 35.80 ? 1022 HIS A ND1 1 ATOM 8059 C CD2 . HIS A 1 1022 ? 63.588 38.062 -7.003 1.00 34.59 ? 1022 HIS A CD2 1 ATOM 8060 C CE1 . HIS A 1 1022 ? 65.208 36.767 -6.278 1.00 37.44 ? 1022 HIS A CE1 1 ATOM 8061 N NE2 . HIS A 1 1022 ? 64.952 37.917 -6.881 1.00 36.21 ? 1022 HIS A NE2 1 ATOM 8062 N N . LEU A 1 1023 ? 60.815 38.094 -9.374 1.00 22.70 ? 1023 LEU A N 1 ATOM 8063 C CA . LEU A 1 1023 ? 60.599 37.840 -10.791 1.00 22.42 ? 1023 LEU A CA 1 ATOM 8064 C C . LEU A 1 1023 ? 61.750 37.237 -11.571 1.00 22.84 ? 1023 LEU A C 1 ATOM 8065 O O . LEU A 1 1023 ? 62.883 37.718 -11.523 1.00 22.36 ? 1023 LEU A O 1 ATOM 8066 C CB . LEU A 1 1023 ? 60.150 39.155 -11.443 1.00 21.48 ? 1023 LEU A CB 1 ATOM 8067 C CG . LEU A 1 1023 ? 58.782 39.508 -10.866 1.00 20.39 ? 1023 LEU A CG 1 ATOM 8068 C CD1 . LEU A 1 1023 ? 58.408 40.944 -11.026 1.00 21.01 ? 1023 LEU A CD1 1 ATOM 8069 C CD2 . LEU A 1 1023 ? 57.799 38.633 -11.557 1.00 20.86 ? 1023 LEU A CD2 1 ATOM 8070 N N . ASP A 1 1024 ? 61.442 36.173 -12.294 1.00 24.33 ? 1024 ASP A N 1 ATOM 8071 C CA . ASP A 1 1024 ? 62.476 35.506 -13.078 1.00 26.61 ? 1024 ASP A CA 1 ATOM 8072 C C . ASP A 1 1024 ? 63.017 36.352 -14.227 1.00 25.95 ? 1024 ASP A C 1 ATOM 8073 O O . ASP A 1 1024 ? 62.254 37.001 -14.954 1.00 27.23 ? 1024 ASP A O 1 ATOM 8074 C CB . ASP A 1 1024 ? 61.943 34.165 -13.563 1.00 29.05 ? 1024 ASP A CB 1 ATOM 8075 C CG . ASP A 1 1024 ? 61.856 33.155 -12.420 1.00 33.06 ? 1024 ASP A CG 1 ATOM 8076 O OD1 . ASP A 1 1024 ? 62.839 33.097 -11.622 1.00 35.36 ? 1024 ASP A OD1 1 ATOM 8077 O OD2 . ASP A 1 1024 ? 60.829 32.438 -12.305 1.00 35.23 ? 1024 ASP A OD2 1 ATOM 8078 N N . GLY A 1 1025 ? 64.339 36.364 -14.368 1.00 25.42 ? 1025 GLY A N 1 ATOM 8079 C CA . GLY A 1 1025 ? 64.970 37.145 -15.421 1.00 24.96 ? 1025 GLY A CA 1 ATOM 8080 C C . GLY A 1 1025 ? 64.989 38.633 -15.128 1.00 24.62 ? 1025 GLY A C 1 ATOM 8081 O O . GLY A 1 1025 ? 65.474 39.432 -15.925 1.00 24.86 ? 1025 GLY A O 1 ATOM 8082 N N . MET A 1 1026 ? 64.486 39.009 -13.961 1.00 24.55 ? 1026 MET A N 1 ATOM 8083 C CA . MET A 1 1026 ? 64.423 40.421 -13.567 1.00 24.81 ? 1026 MET A CA 1 ATOM 8084 C C . MET A 1 1026 ? 63.548 41.186 -14.565 1.00 22.79 ? 1026 MET A C 1 ATOM 8085 O O . MET A 1 1026 ? 63.786 42.353 -14.834 1.00 21.97 ? 1026 MET A O 1 ATOM 8086 C CB . MET A 1 1026 ? 65.831 41.043 -13.474 1.00 26.56 ? 1026 MET A CB 1 ATOM 8087 C CG . MET A 1 1026 ? 66.815 40.144 -12.716 1.00 30.93 ? 1026 MET A CG 1 ATOM 8088 S SD . MET A 1 1026 ? 68.384 40.945 -12.453 1.00 36.03 ? 1026 MET A SD 1 ATOM 8089 C CE . MET A 1 1026 ? 69.116 40.821 -14.073 1.00 35.32 ? 1026 MET A CE 1 ATOM 8090 N N . VAL A 1 1027 ? 62.537 40.492 -15.086 1.00 20.49 ? 1027 VAL A N 1 ATOM 8091 C CA . VAL A 1 1027 ? 61.563 41.031 -16.050 1.00 21.67 ? 1027 VAL A CA 1 ATOM 8092 C C . VAL A 1 1027 ? 60.205 41.248 -15.385 1.00 21.87 ? 1027 VAL A C 1 ATOM 8093 O O . VAL A 1 1027 ? 59.690 40.371 -14.703 1.00 22.75 ? 1027 VAL A O 1 ATOM 8094 C CB . VAL A 1 1027 ? 61.388 40.047 -17.257 1.00 20.20 ? 1027 VAL A CB 1 ATOM 8095 C CG1 . VAL A 1 1027 ? 60.217 40.472 -18.173 1.00 20.21 ? 1027 VAL A CG1 1 ATOM 8096 C CG2 . VAL A 1 1027 ? 62.665 39.985 -18.037 1.00 20.27 ? 1027 VAL A CG2 1 ATOM 8097 N N . ALA A 1 1028 ? 59.649 42.445 -15.550 1.00 21.35 ? 1028 ALA A N 1 ATOM 8098 C CA . ALA A 1 1028 ? 58.319 42.783 -15.027 1.00 20.99 ? 1028 ALA A CA 1 ATOM 8099 C C . ALA A 1 1028 ? 57.336 42.564 -16.161 1.00 21.11 ? 1028 ALA A C 1 ATOM 8100 O O . ALA A 1 1028 ? 57.404 43.268 -17.184 1.00 23.04 ? 1028 ALA A O 1 ATOM 8101 C CB . ALA A 1 1028 ? 58.263 44.225 -14.615 1.00 20.19 ? 1028 ALA A CB 1 ATOM 8102 N N . PRO A 1 1029 ? 56.439 41.588 -16.029 1.00 20.25 ? 1029 PRO A N 1 ATOM 8103 C CA . PRO A 1 1029 ? 55.431 41.299 -17.053 1.00 20.66 ? 1029 PRO A CA 1 ATOM 8104 C C . PRO A 1 1029 ? 54.516 42.525 -17.244 1.00 21.18 ? 1029 PRO A C 1 ATOM 8105 O O . PRO A 1 1029 ? 54.574 43.456 -16.472 1.00 23.79 ? 1029 PRO A O 1 ATOM 8106 C CB . PRO A 1 1029 ? 54.637 40.139 -16.461 1.00 20.16 ? 1029 PRO A CB 1 ATOM 8107 C CG . PRO A 1 1029 ? 55.622 39.517 -15.401 1.00 18.85 ? 1029 PRO A CG 1 ATOM 8108 C CD . PRO A 1 1029 ? 56.335 40.696 -14.857 1.00 20.17 ? 1029 PRO A CD 1 ATOM 8109 N N . GLU A 1 1030 ? 53.728 42.555 -18.307 1.00 20.88 ? 1030 GLU A N 1 ATOM 8110 C CA . GLU A 1 1030 ? 52.781 43.649 -18.432 1.00 19.89 ? 1030 GLU A CA 1 ATOM 8111 C C . GLU A 1 1030 ? 51.539 43.115 -17.703 1.00 19.97 ? 1030 GLU A C 1 ATOM 8112 O O . GLU A 1 1030 ? 51.498 41.932 -17.352 1.00 22.56 ? 1030 GLU A O 1 ATOM 8113 C CB . GLU A 1 1030 ? 52.469 43.930 -19.898 1.00 20.81 ? 1030 GLU A CB 1 ATOM 8114 C CG . GLU A 1 1030 ? 53.672 44.560 -20.573 1.00 20.23 ? 1030 GLU A CG 1 ATOM 8115 C CD . GLU A 1 1030 ? 53.368 45.020 -21.988 1.00 19.18 ? 1030 GLU A CD 1 ATOM 8116 O OE1 . GLU A 1 1030 ? 52.335 44.567 -22.537 1.00 21.37 ? 1030 GLU A OE1 1 ATOM 8117 O OE2 . GLU A 1 1030 ? 54.165 45.817 -22.528 1.00 19.00 ? 1030 GLU A OE2 1 ATOM 8118 N N . VAL A 1 1031 ? 50.538 43.967 -17.498 1.00 17.59 ? 1031 VAL A N 1 ATOM 8119 C CA . VAL A 1 1031 ? 49.336 43.550 -16.770 1.00 16.33 ? 1031 VAL A CA 1 ATOM 8120 C C . VAL A 1 1031 ? 48.154 43.313 -17.691 1.00 16.19 ? 1031 VAL A C 1 ATOM 8121 O O . VAL A 1 1031 ? 48.216 43.667 -18.853 1.00 17.27 ? 1031 VAL A O 1 ATOM 8122 C CB . VAL A 1 1031 ? 48.948 44.591 -15.689 1.00 17.53 ? 1031 VAL A CB 1 ATOM 8123 C CG1 . VAL A 1 1031 ? 50.108 44.758 -14.661 1.00 17.46 ? 1031 VAL A CG1 1 ATOM 8124 C CG2 . VAL A 1 1031 ? 48.615 45.938 -16.335 1.00 15.59 ? 1031 VAL A CG2 1 ATOM 8125 N N . CYS A 1 1032 ? 47.089 42.682 -17.189 1.00 13.95 ? 1032 CYS A N 1 ATOM 8126 C CA . CYS A 1 1032 ? 45.914 42.400 -17.979 1.00 14.71 ? 1032 CYS A CA 1 ATOM 8127 C C . CYS A 1 1032 ? 44.990 43.602 -18.049 1.00 13.76 ? 1032 CYS A C 1 ATOM 8128 O O . CYS A 1 1032 ? 45.142 44.525 -17.298 1.00 10.32 ? 1032 CYS A O 1 ATOM 8129 C CB . CYS A 1 1032 ? 45.104 41.226 -17.377 1.00 16.36 ? 1032 CYS A CB 1 ATOM 8130 S SG . CYS A 1 1032 ? 45.918 39.596 -17.517 1.00 19.55 ? 1032 CYS A SG 1 ATOM 8131 N N . PRO A 1 1033 ? 44.060 43.621 -19.031 1.00 11.83 ? 1033 PRO A N 1 ATOM 8132 C CA . PRO A 1 1033 ? 43.131 44.748 -19.116 1.00 10.30 ? 1033 PRO A CA 1 ATOM 8133 C C . PRO A 1 1033 ? 42.404 44.924 -17.786 1.00 9.75 ? 1033 PRO A C 1 ATOM 8134 O O . PRO A 1 1033 ? 41.891 43.955 -17.225 1.00 11.05 ? 1033 PRO A O 1 ATOM 8135 C CB . PRO A 1 1033 ? 42.130 44.302 -20.194 1.00 11.19 ? 1033 PRO A CB 1 ATOM 8136 C CG . PRO A 1 1033 ? 42.968 43.470 -21.100 1.00 11.06 ? 1033 PRO A CG 1 ATOM 8137 C CD . PRO A 1 1033 ? 43.908 42.706 -20.188 1.00 14.18 ? 1033 PRO A CD 1 ATOM 8138 N N . MET A 1 1034 ? 42.351 46.177 -17.344 1.00 9.89 ? 1034 MET A N 1 ATOM 8139 C CA . MET A 1 1034 ? 41.681 46.572 -16.090 1.00 10.66 ? 1034 MET A CA 1 ATOM 8140 C C . MET A 1 1034 ? 42.480 46.246 -14.830 1.00 13.58 ? 1034 MET A C 1 ATOM 8141 O O . MET A 1 1034 ? 42.037 46.532 -13.716 1.00 13.89 ? 1034 MET A O 1 ATOM 8142 C CB . MET A 1 1034 ? 40.197 46.115 -16.030 1.00 9.66 ? 1034 MET A CB 1 ATOM 8143 C CG . MET A 1 1034 ? 39.351 46.652 -17.182 1.00 11.24 ? 1034 MET A CG 1 ATOM 8144 S SD . MET A 1 1034 ? 39.328 48.453 -17.237 1.00 13.66 ? 1034 MET A SD 1 ATOM 8145 C CE . MET A 1 1034 ? 38.237 48.999 -15.857 1.00 16.06 ? 1034 MET A CE 1 ATOM 8146 N N . GLU A 1 1035 ? 43.656 45.680 -14.983 1.00 12.28 ? 1035 GLU A N 1 ATOM 8147 C CA . GLU A 1 1035 ? 44.478 45.362 -13.821 1.00 12.49 ? 1035 GLU A CA 1 ATOM 8148 C C . GLU A 1 1035 ? 45.524 46.387 -13.617 1.00 13.13 ? 1035 GLU A C 1 ATOM 8149 O O . GLU A 1 1035 ? 45.846 47.099 -14.534 1.00 11.38 ? 1035 GLU A O 1 ATOM 8150 C CB . GLU A 1 1035 ? 45.120 43.983 -13.980 1.00 16.68 ? 1035 GLU A CB 1 ATOM 8151 C CG . GLU A 1 1035 ? 44.066 42.841 -13.825 1.00 21.55 ? 1035 GLU A CG 1 ATOM 8152 C CD . GLU A 1 1035 ? 43.547 42.732 -12.378 1.00 26.78 ? 1035 GLU A CD 1 ATOM 8153 O OE1 . GLU A 1 1035 ? 44.275 43.200 -11.461 1.00 30.31 ? 1035 GLU A OE1 1 ATOM 8154 O OE2 . GLU A 1 1035 ? 42.436 42.167 -12.160 1.00 29.36 ? 1035 GLU A OE2 1 ATOM 8155 N N . THR A 1 1036 ? 46.026 46.465 -12.380 1.00 9.85 ? 1036 THR A N 1 ATOM 8156 C CA . THR A 1 1036 ? 47.082 47.406 -11.974 1.00 10.20 ? 1036 THR A CA 1 ATOM 8157 C C . THR A 1 1036 ? 48.062 46.564 -11.155 1.00 9.09 ? 1036 THR A C 1 ATOM 8158 O O . THR A 1 1036 ? 47.647 45.775 -10.278 1.00 11.33 ? 1036 THR A O 1 ATOM 8159 C CB . THR A 1 1036 ? 46.525 48.565 -11.096 1.00 9.36 ? 1036 THR A CB 1 ATOM 8160 O OG1 . THR A 1 1036 ? 45.429 49.181 -11.808 1.00 10.44 ? 1036 THR A OG1 1 ATOM 8161 C CG2 . THR A 1 1036 ? 47.568 49.616 -10.798 1.00 12.38 ? 1036 THR A CG2 1 ATOM 8162 N N . ALA A 1 1037 ? 49.351 46.694 -11.465 1.00 9.62 ? 1037 ALA A N 1 ATOM 8163 C CA . ALA A 1 1037 ? 50.408 46.014 -10.694 1.00 10.35 ? 1037 ALA A CA 1 ATOM 8164 C C . ALA A 1 1037 ? 51.494 47.000 -10.338 1.00 10.24 ? 1037 ALA A C 1 ATOM 8165 O O . ALA A 1 1037 ? 51.580 48.089 -10.922 1.00 12.64 ? 1037 ALA A O 1 ATOM 8166 C CB . ALA A 1 1037 ? 51.008 44.912 -11.508 1.00 11.57 ? 1037 ALA A CB 1 ATOM 8167 N N . ALA A 1 1038 ? 52.319 46.615 -9.370 1.00 8.64 ? 1038 ALA A N 1 ATOM 8168 C CA . ALA A 1 1038 ? 53.446 47.397 -8.955 1.00 8.50 ? 1038 ALA A CA 1 ATOM 8169 C C . ALA A 1 1038 ? 54.710 46.562 -8.998 1.00 9.95 ? 1038 ALA A C 1 ATOM 8170 O O . ALA A 1 1038 ? 54.683 45.388 -8.725 1.00 10.03 ? 1038 ALA A O 1 ATOM 8171 C CB . ALA A 1 1038 ? 53.203 48.002 -7.547 1.00 8.99 ? 1038 ALA A CB 1 ATOM 8172 N N . TYR A 1 1039 ? 55.802 47.208 -9.376 1.00 9.85 ? 1039 TYR A N 1 ATOM 8173 C CA . TYR A 1 1039 ? 57.082 46.528 -9.446 1.00 11.11 ? 1039 TYR A CA 1 ATOM 8174 C C . TYR A 1 1039 ? 58.143 47.397 -8.860 1.00 11.98 ? 1039 TYR A C 1 ATOM 8175 O O . TYR A 1 1039 ? 58.082 48.625 -8.961 1.00 12.47 ? 1039 TYR A O 1 ATOM 8176 C CB . TYR A 1 1039 ? 57.489 46.178 -10.907 1.00 11.39 ? 1039 TYR A CB 1 ATOM 8177 C CG . TYR A 1 1039 ? 56.526 45.287 -11.628 1.00 10.23 ? 1039 TYR A CG 1 ATOM 8178 C CD1 . TYR A 1 1039 ? 56.469 43.873 -11.397 1.00 9.59 ? 1039 TYR A CD1 1 ATOM 8179 C CD2 . TYR A 1 1039 ? 55.597 45.817 -12.510 1.00 13.36 ? 1039 TYR A CD2 1 ATOM 8180 C CE1 . TYR A 1 1039 ? 55.511 43.077 -12.026 1.00 11.54 ? 1039 TYR A CE1 1 ATOM 8181 C CE2 . TYR A 1 1039 ? 54.660 45.008 -13.137 1.00 12.77 ? 1039 TYR A CE2 1 ATOM 8182 C CZ . TYR A 1 1039 ? 54.612 43.658 -12.904 1.00 13.85 ? 1039 TYR A CZ 1 ATOM 8183 O OH . TYR A 1 1039 ? 53.693 42.863 -13.574 1.00 15.42 ? 1039 TYR A OH 1 ATOM 8184 N N . VAL A 1 1040 ? 59.147 46.754 -8.254 1.00 10.70 ? 1040 VAL A N 1 ATOM 8185 C CA . VAL A 1 1040 ? 60.278 47.466 -7.701 1.00 12.02 ? 1040 VAL A CA 1 ATOM 8186 C C . VAL A 1 1040 ? 61.545 46.805 -8.235 1.00 12.98 ? 1040 VAL A C 1 ATOM 8187 O O . VAL A 1 1040 ? 61.714 45.555 -8.140 1.00 13.76 ? 1040 VAL A O 1 ATOM 8188 C CB . VAL A 1 1040 ? 60.325 47.418 -6.156 1.00 10.14 ? 1040 VAL A CB 1 ATOM 8189 C CG1 . VAL A 1 1040 ? 61.703 48.053 -5.609 1.00 12.65 ? 1040 VAL A CG1 1 ATOM 8190 C CG2 . VAL A 1 1040 ? 59.137 48.183 -5.626 1.00 12.50 ? 1040 VAL A CG2 1 ATOM 8191 N N . SER A 1 1041 ? 62.369 47.594 -8.922 1.00 12.20 ? 1041 SER A N 1 ATOM 8192 C CA . SER A 1 1041 ? 63.635 47.099 -9.460 1.00 13.39 ? 1041 SER A CA 1 ATOM 8193 C C . SER A 1 1041 ? 64.741 47.601 -8.518 1.00 13.27 ? 1041 SER A C 1 ATOM 8194 O O . SER A 1 1041 ? 64.677 48.711 -7.995 1.00 13.75 ? 1041 SER A O 1 ATOM 8195 C CB . SER A 1 1041 ? 63.855 47.595 -10.912 1.00 14.71 ? 1041 SER A CB 1 ATOM 8196 O OG . SER A 1 1041 ? 63.916 49.016 -11.054 1.00 14.47 ? 1041 SER A OG 1 ATOM 8197 N N . SER A 1 1042 ? 65.739 46.732 -8.291 1.00 12.71 ? 1042 SER A N 1 ATOM 8198 C CA . SER A 1 1042 ? 66.870 47.037 -7.427 1.00 14.39 ? 1042 SER A CA 1 ATOM 8199 C C . SER A 1 1042 ? 68.100 47.035 -8.347 1.00 12.36 ? 1042 SER A C 1 ATOM 8200 O O . SER A 1 1042 ? 68.227 46.194 -9.264 1.00 16.31 ? 1042 SER A O 1 ATOM 8201 C CB . SER A 1 1042 ? 67.024 45.961 -6.363 1.00 14.18 ? 1042 SER A CB 1 ATOM 8202 O OG . SER A 1 1042 ? 65.855 45.919 -5.552 1.00 15.91 ? 1042 SER A OG 1 ATOM 8203 N N . HIS A 1 1043 ? 68.976 48.010 -8.073 1.00 15.13 ? 1043 HIS A N 1 ATOM 8204 C CA . HIS A 1 1043 ? 70.174 48.277 -8.886 1.00 16.60 ? 1043 HIS A CA 1 ATOM 8205 C C . HIS A 1 1043 ? 71.405 48.425 -7.974 1.00 19.24 ? 1043 HIS A C 1 ATOM 8206 O O . HIS A 1 1043 ? 71.385 49.117 -6.960 1.00 18.48 ? 1043 HIS A O 1 ATOM 8207 C CB . HIS A 1 1043 ? 69.913 49.584 -9.657 1.00 16.92 ? 1043 HIS A CB 1 ATOM 8208 C CG . HIS A 1 1043 ? 68.622 49.569 -10.427 1.00 17.29 ? 1043 HIS A CG 1 ATOM 8209 N ND1 . HIS A 1 1043 ? 68.537 49.151 -11.735 1.00 15.42 ? 1043 HIS A ND1 1 ATOM 8210 C CD2 . HIS A 1 1043 ? 67.349 49.832 -10.033 1.00 16.08 ? 1043 HIS A CD2 1 ATOM 8211 C CE1 . HIS A 1 1043 ? 67.268 49.148 -12.114 1.00 16.92 ? 1043 HIS A CE1 1 ATOM 8212 N NE2 . HIS A 1 1043 ? 66.532 49.558 -11.095 1.00 16.12 ? 1043 HIS A NE2 1 ATOM 8213 N N . SER A 1 1044 ? 72.488 47.771 -8.361 1.00 22.56 ? 1044 SER A N 1 ATOM 8214 C CA . SER A 1 1044 ? 73.686 47.808 -7.544 1.00 27.53 ? 1044 SER A CA 1 ATOM 8215 C C . SER A 1 1044 ? 74.707 48.761 -8.077 1.00 29.72 ? 1044 SER A C 1 ATOM 8216 O O . SER A 1 1044 ? 75.880 48.319 -7.972 1.00 31.03 ? 1044 SER A O 1 ATOM 8217 C CB . SER A 1 1044 ? 74.327 46.414 -7.500 1.00 29.45 ? 1044 SER A CB 1 ATOM 8218 O OG . SER A 1 1044 ? 74.288 45.813 -8.793 1.00 32.26 ? 1044 SER A OG 1 HETATM 8219 C C1 . NAG B 2 . ? 58.494 44.695 12.939 1.00 35.35 ? 5004 NAG A C1 1 HETATM 8220 C C2 . NAG B 2 . ? 59.470 44.192 14.018 1.00 38.49 ? 5004 NAG A C2 1 HETATM 8221 C C3 . NAG B 2 . ? 59.888 42.764 13.659 1.00 40.63 ? 5004 NAG A C3 1 HETATM 8222 C C4 . NAG B 2 . ? 58.645 41.914 13.697 1.00 41.18 ? 5004 NAG A C4 1 HETATM 8223 C C5 . NAG B 2 . ? 57.659 42.425 12.643 1.00 41.26 ? 5004 NAG A C5 1 HETATM 8224 C C6 . NAG B 2 . ? 56.354 41.675 12.773 1.00 42.33 ? 5004 NAG A C6 1 HETATM 8225 C C7 . NAG B 2 . ? 61.422 45.302 13.087 1.00 42.28 ? 5004 NAG A C7 1 HETATM 8226 C C8 . NAG B 2 . ? 62.717 44.503 13.000 1.00 43.26 ? 5004 NAG A C8 1 HETATM 8227 N N2 . NAG B 2 . ? 60.622 45.074 14.134 1.00 40.58 ? 5004 NAG A N2 1 HETATM 8228 O O3 . NAG B 2 . ? 60.839 42.265 14.587 1.00 41.95 ? 5004 NAG A O3 1 HETATM 8229 O O4 . NAG B 2 . ? 58.978 40.551 13.464 1.00 43.37 ? 5004 NAG A O4 1 HETATM 8230 O O5 . NAG B 2 . ? 57.346 43.832 12.865 1.00 38.07 ? 5004 NAG A O5 1 HETATM 8231 O O6 . NAG B 2 . ? 55.944 41.626 14.143 1.00 43.41 ? 5004 NAG A O6 1 HETATM 8232 O O7 . NAG B 2 . ? 61.166 46.134 12.211 1.00 43.15 ? 5004 NAG A O7 1 HETATM 8233 ZN ZN . ZN C 3 . ? 34.587 63.998 8.223 1.00 8.43 ? 5001 ZN A ZN 1 HETATM 8234 P P . PO4 D 4 . ? 45.535 66.582 -28.444 1.00 28.67 ? 5005 PO4 A P 1 HETATM 8235 O O1 . PO4 D 4 . ? 44.601 67.377 -29.460 1.00 32.15 ? 5005 PO4 A O1 1 HETATM 8236 O O2 . PO4 D 4 . ? 46.902 66.268 -29.050 1.00 31.93 ? 5005 PO4 A O2 1 HETATM 8237 O O3 . PO4 D 4 . ? 44.798 65.251 -28.088 1.00 29.72 ? 5005 PO4 A O3 1 HETATM 8238 O O4 . PO4 D 4 . ? 45.706 67.534 -27.195 1.00 29.84 ? 5005 PO4 A O4 1 HETATM 8239 C C5 . MSN E 5 . ? 31.319 65.877 9.450 1.00 9.46 ? 5002 MSN A C5 1 HETATM 8240 N N5 . MSN E 5 . ? 31.148 64.508 9.944 1.00 9.35 ? 5002 MSN A N5 1 HETATM 8241 C C4 . MSN E 5 . ? 32.801 66.188 9.512 1.00 8.64 ? 5002 MSN A C4 1 HETATM 8242 O O4 . MSN E 5 . ? 33.622 65.088 9.913 1.00 9.38 ? 5002 MSN A O4 1 HETATM 8243 C C3 . MSN E 5 . ? 33.074 66.715 8.099 1.00 10.63 ? 5002 MSN A C3 1 HETATM 8244 O O3 . MSN E 5 . ? 33.836 65.824 7.291 1.00 8.47 ? 5002 MSN A O3 1 HETATM 8245 C C2 . MSN E 5 . ? 31.799 67.049 7.331 1.00 9.08 ? 5002 MSN A C2 1 HETATM 8246 O O2 . MSN E 5 . ? 31.766 67.289 5.923 1.00 7.80 ? 5002 MSN A O2 1 HETATM 8247 C C1 . MSN E 5 . ? 30.936 65.949 7.979 1.00 8.48 ? 5002 MSN A C1 1 HETATM 8248 S S6 . MSN E 5 . ? 29.232 66.518 8.017 1.00 12.15 ? 5002 MSN A S6 1 HETATM 8249 C C7 A MSN E 5 . ? 28.420 65.373 9.143 0.50 5.26 ? 5002 MSN A C7 1 HETATM 8250 C C7 B MSN E 5 . ? 28.591 66.069 6.397 0.50 6.80 ? 5002 MSN A C7 1 HETATM 8251 C C1 . MPD F 6 . ? 16.492 62.332 10.510 1.00 23.24 ? 5003 MPD A C1 1 HETATM 8252 C C2 . MPD F 6 . ? 16.161 60.865 10.698 1.00 23.18 ? 5003 MPD A C2 1 HETATM 8253 O O2 . MPD F 6 . ? 14.757 60.715 10.334 1.00 21.65 ? 5003 MPD A O2 1 HETATM 8254 C CM . MPD F 6 . ? 16.974 59.981 9.750 1.00 21.67 ? 5003 MPD A CM 1 HETATM 8255 C C3 . MPD F 6 . ? 16.269 60.422 12.206 1.00 21.42 ? 5003 MPD A C3 1 HETATM 8256 C C4 . MPD F 6 . ? 17.663 60.324 12.886 1.00 21.62 ? 5003 MPD A C4 1 HETATM 8257 O O4 . MPD F 6 . ? 17.636 59.429 13.997 1.00 15.83 ? 5003 MPD A O4 1 HETATM 8258 C C5 . MPD F 6 . ? 18.169 61.680 13.447 1.00 23.04 ? 5003 MPD A C5 1 HETATM 8259 O O . HOH G 7 . ? 28.098 47.042 -31.468 1.00 28.51 ? 5006 HOH A O 1 HETATM 8260 O O . HOH G 7 . ? 28.476 44.381 -29.510 1.00 36.08 ? 5007 HOH A O 1 HETATM 8261 O O . HOH G 7 . ? 26.394 44.243 -27.394 1.00 36.23 ? 5008 HOH A O 1 HETATM 8262 O O . HOH G 7 . ? 27.022 41.781 -27.468 1.00 29.73 ? 5009 HOH A O 1 HETATM 8263 O O . HOH G 7 . ? 29.337 41.323 -25.570 1.00 25.13 ? 5010 HOH A O 1 HETATM 8264 O O . HOH G 7 . ? 28.072 39.243 -24.949 1.00 35.96 ? 5011 HOH A O 1 HETATM 8265 O O . HOH G 7 . ? 27.837 38.968 -22.627 1.00 29.05 ? 5012 HOH A O 1 HETATM 8266 O O . HOH G 7 . ? 28.735 41.328 -21.637 1.00 16.09 ? 5013 HOH A O 1 HETATM 8267 O O . HOH G 7 . ? 27.603 36.652 -19.717 1.00 26.63 ? 5014 HOH A O 1 HETATM 8268 O O . HOH G 7 . ? 25.974 36.473 -15.612 1.00 29.70 ? 5015 HOH A O 1 HETATM 8269 O O . HOH G 7 . ? 24.585 39.064 -11.556 1.00 25.94 ? 5016 HOH A O 1 HETATM 8270 O O . HOH G 7 . ? 22.220 40.472 -11.374 1.00 34.47 ? 5017 HOH A O 1 HETATM 8271 O O . HOH G 7 . ? 21.954 40.263 -8.867 1.00 27.51 ? 5018 HOH A O 1 HETATM 8272 O O . HOH G 7 . ? 20.884 42.700 -7.364 1.00 18.30 ? 5019 HOH A O 1 HETATM 8273 O O . HOH G 7 . ? 19.838 41.777 -5.110 1.00 28.04 ? 5020 HOH A O 1 HETATM 8274 O O . HOH G 7 . ? 19.260 42.595 -2.404 1.00 25.12 ? 5021 HOH A O 1 HETATM 8275 O O . HOH G 7 . ? 16.660 42.752 -2.424 1.00 24.35 ? 5022 HOH A O 1 HETATM 8276 O O . HOH G 7 . ? 20.000 38.953 -3.676 1.00 34.83 ? 5023 HOH A O 1 HETATM 8277 O O . HOH G 7 . ? 20.888 35.893 -4.507 1.00 37.24 ? 5024 HOH A O 1 HETATM 8278 O O . HOH G 7 . ? 22.092 36.606 0.145 1.00 21.13 ? 5025 HOH A O 1 HETATM 8279 O O . HOH G 7 . ? 23.646 34.515 -0.002 1.00 51.50 ? 5026 HOH A O 1 HETATM 8280 O O . HOH G 7 . ? 23.083 31.930 2.025 1.00 46.01 ? 5027 HOH A O 1 HETATM 8281 O O . HOH G 7 . ? 24.883 32.705 6.487 1.00 19.91 ? 5028 HOH A O 1 HETATM 8282 O O . HOH G 7 . ? 24.650 32.786 9.455 1.00 23.43 ? 5029 HOH A O 1 HETATM 8283 O O . HOH G 7 . ? 25.222 33.374 13.364 1.00 31.28 ? 5030 HOH A O 1 HETATM 8284 O O . HOH G 7 . ? 24.295 34.035 15.555 1.00 23.13 ? 5031 HOH A O 1 HETATM 8285 O O . HOH G 7 . ? 23.345 36.445 13.271 1.00 23.38 ? 5032 HOH A O 1 HETATM 8286 O O . HOH G 7 . ? 22.297 33.997 12.454 1.00 35.69 ? 5033 HOH A O 1 HETATM 8287 O O . HOH G 7 . ? 20.509 37.658 12.291 1.00 22.95 ? 5034 HOH A O 1 HETATM 8288 O O . HOH G 7 . ? 21.731 37.742 15.719 1.00 17.75 ? 5035 HOH A O 1 HETATM 8289 O O . HOH G 7 . ? 19.776 38.785 17.534 1.00 17.54 ? 5036 HOH A O 1 HETATM 8290 O O . HOH G 7 . ? 18.611 37.286 19.837 1.00 28.23 ? 5037 HOH A O 1 HETATM 8291 O O . HOH G 7 . ? 19.207 36.248 22.283 1.00 26.47 ? 5038 HOH A O 1 HETATM 8292 O O . HOH G 7 . ? 19.832 35.271 25.480 1.00 27.37 ? 5039 HOH A O 1 HETATM 8293 O O . HOH G 7 . ? 17.072 33.447 26.681 1.00 45.82 ? 5040 HOH A O 1 HETATM 8294 O O . HOH G 7 . ? 18.288 31.768 25.507 1.00 34.98 ? 5041 HOH A O 1 HETATM 8295 O O . HOH G 7 . ? 14.034 33.556 27.091 1.00 38.41 ? 5042 HOH A O 1 HETATM 8296 O O . HOH G 7 . ? 18.085 37.985 29.359 1.00 52.00 ? 5043 HOH A O 1 HETATM 8297 O O . HOH G 7 . ? 19.021 38.953 26.409 1.00 31.03 ? 5044 HOH A O 1 HETATM 8298 O O . HOH G 7 . ? 17.846 41.550 25.388 1.00 31.49 ? 5045 HOH A O 1 HETATM 8299 O O . HOH G 7 . ? 14.583 44.316 27.215 1.00 42.06 ? 5046 HOH A O 1 HETATM 8300 O O . HOH G 7 . ? 12.926 45.380 28.379 1.00 51.51 ? 5047 HOH A O 1 HETATM 8301 O O . HOH G 7 . ? 14.011 47.199 26.673 1.00 37.40 ? 5048 HOH A O 1 HETATM 8302 O O . HOH G 7 . ? 16.401 48.758 24.126 1.00 12.53 ? 5049 HOH A O 1 HETATM 8303 O O . HOH G 7 . ? 13.947 50.156 24.242 1.00 22.66 ? 5050 HOH A O 1 HETATM 8304 O O . HOH G 7 . ? 12.811 51.843 25.755 1.00 31.27 ? 5051 HOH A O 1 HETATM 8305 O O . HOH G 7 . ? 12.916 54.639 25.306 1.00 32.13 ? 5052 HOH A O 1 HETATM 8306 O O . HOH G 7 . ? 14.450 55.146 27.606 1.00 31.06 ? 5053 HOH A O 1 HETATM 8307 O O . HOH G 7 . ? 14.512 54.253 29.711 1.00 36.33 ? 5054 HOH A O 1 HETATM 8308 O O . HOH G 7 . ? 18.235 59.033 31.684 1.00 39.76 ? 5055 HOH A O 1 HETATM 8309 O O . HOH G 7 . ? 23.016 55.699 31.002 1.00 16.56 ? 5056 HOH A O 1 HETATM 8310 O O . HOH G 7 . ? 24.110 60.547 36.157 1.00 34.49 ? 5057 HOH A O 1 HETATM 8311 O O . HOH G 7 . ? 22.362 62.677 33.776 1.00 31.27 ? 5058 HOH A O 1 HETATM 8312 O O . HOH G 7 . ? 22.176 65.156 32.548 1.00 28.06 ? 5059 HOH A O 1 HETATM 8313 O O . HOH G 7 . ? 22.380 66.076 29.144 1.00 25.32 ? 5060 HOH A O 1 HETATM 8314 O O . HOH G 7 . ? 20.270 65.308 27.345 1.00 28.96 ? 5061 HOH A O 1 HETATM 8315 O O . HOH G 7 . ? 17.778 65.765 28.160 1.00 28.90 ? 5062 HOH A O 1 HETATM 8316 O O . HOH G 7 . ? 18.276 66.307 30.717 1.00 42.39 ? 5063 HOH A O 1 HETATM 8317 O O . HOH G 7 . ? 16.918 65.114 32.315 1.00 42.93 ? 5064 HOH A O 1 HETATM 8318 O O . HOH G 7 . ? 13.867 68.935 26.232 1.00 34.12 ? 5065 HOH A O 1 HETATM 8319 O O . HOH G 7 . ? 15.280 69.106 23.859 1.00 38.31 ? 5066 HOH A O 1 HETATM 8320 O O . HOH G 7 . ? 13.064 69.383 22.825 1.00 37.74 ? 5067 HOH A O 1 HETATM 8321 O O . HOH G 7 . ? 15.632 68.100 21.500 1.00 30.16 ? 5068 HOH A O 1 HETATM 8322 O O . HOH G 7 . ? 20.377 67.922 22.413 1.00 23.09 ? 5069 HOH A O 1 HETATM 8323 O O . HOH G 7 . ? 22.371 67.881 20.637 1.00 26.51 ? 5070 HOH A O 1 HETATM 8324 O O . HOH G 7 . ? 24.761 67.979 22.015 1.00 19.87 ? 5071 HOH A O 1 HETATM 8325 O O . HOH G 7 . ? 25.130 70.773 21.991 1.00 31.02 ? 5072 HOH A O 1 HETATM 8326 O O . HOH G 7 . ? 29.178 71.851 21.942 1.00 32.73 ? 5073 HOH A O 1 HETATM 8327 O O . HOH G 7 . ? 32.545 68.966 24.050 1.00 26.70 ? 5074 HOH A O 1 HETATM 8328 O O . HOH G 7 . ? 35.555 68.507 23.414 1.00 30.27 ? 5075 HOH A O 1 HETATM 8329 O O . HOH G 7 . ? 36.445 70.716 23.485 1.00 35.15 ? 5076 HOH A O 1 HETATM 8330 O O . HOH G 7 . ? 35.734 67.574 20.755 1.00 24.74 ? 5077 HOH A O 1 HETATM 8331 O O . HOH G 7 . ? 33.148 66.500 21.389 1.00 18.07 ? 5078 HOH A O 1 HETATM 8332 O O . HOH G 7 . ? 31.854 65.127 19.243 1.00 14.58 ? 5079 HOH A O 1 HETATM 8333 O O . HOH G 7 . ? 29.799 66.615 18.229 1.00 32.56 ? 5080 HOH A O 1 HETATM 8334 O O . HOH G 7 . ? 29.179 65.446 15.796 1.00 22.21 ? 5081 HOH A O 1 HETATM 8335 O O . HOH G 7 . ? 30.360 66.948 13.403 1.00 30.41 ? 5082 HOH A O 1 HETATM 8336 O O . HOH G 7 . ? 28.074 67.607 11.542 1.00 31.95 ? 5083 HOH A O 1 HETATM 8337 O O . HOH G 7 . ? 26.202 66.951 10.077 1.00 28.19 ? 5084 HOH A O 1 HETATM 8338 O O . HOH G 7 . ? 25.930 65.113 8.614 1.00 30.84 ? 5085 HOH A O 1 HETATM 8339 O O . HOH G 7 . ? 24.195 63.236 7.625 1.00 14.96 ? 5086 HOH A O 1 HETATM 8340 O O . HOH G 7 . ? 24.667 61.190 9.234 1.00 15.98 ? 5087 HOH A O 1 HETATM 8341 O O . HOH G 7 . ? 27.187 60.848 10.486 1.00 22.83 ? 5088 HOH A O 1 HETATM 8342 O O . HOH G 7 . ? 27.108 59.075 8.639 1.00 18.58 ? 5089 HOH A O 1 HETATM 8343 O O . HOH G 7 . ? 23.872 57.917 6.460 1.00 8.50 ? 5090 HOH A O 1 HETATM 8344 O O . HOH G 7 . ? 21.703 56.929 5.166 1.00 10.23 ? 5091 HOH A O 1 HETATM 8345 O O . HOH G 7 . ? 20.164 55.808 7.237 1.00 13.37 ? 5092 HOH A O 1 HETATM 8346 O O . HOH G 7 . ? 19.359 53.350 8.201 1.00 11.04 ? 5093 HOH A O 1 HETATM 8347 O O . HOH G 7 . ? 17.571 52.484 6.395 1.00 12.26 ? 5094 HOH A O 1 HETATM 8348 O O . HOH G 7 . ? 13.781 53.881 4.457 1.00 12.34 ? 5095 HOH A O 1 HETATM 8349 O O . HOH G 7 . ? 13.374 53.474 1.858 1.00 14.66 ? 5096 HOH A O 1 HETATM 8350 O O . HOH G 7 . ? 14.577 49.959 0.808 1.00 36.67 ? 5097 HOH A O 1 HETATM 8351 O O . HOH G 7 . ? 13.320 51.015 -1.683 1.00 32.31 ? 5098 HOH A O 1 HETATM 8352 O O . HOH G 7 . ? 11.834 47.525 -2.919 1.00 34.24 ? 5099 HOH A O 1 HETATM 8353 O O . HOH G 7 . ? 7.965 52.804 -7.091 1.00 32.24 ? 5100 HOH A O 1 HETATM 8354 O O . HOH G 7 . ? 8.711 54.727 -6.058 1.00 32.90 ? 5101 HOH A O 1 HETATM 8355 O O . HOH G 7 . ? 9.830 56.867 -5.734 1.00 24.86 ? 5102 HOH A O 1 HETATM 8356 O O . HOH G 7 . ? 11.931 59.386 -4.839 1.00 20.39 ? 5103 HOH A O 1 HETATM 8357 O O . HOH G 7 . ? 14.100 59.660 -3.166 1.00 15.73 ? 5104 HOH A O 1 HETATM 8358 O O . HOH G 7 . ? 14.079 57.832 -1.242 1.00 21.01 ? 5105 HOH A O 1 HETATM 8359 O O . HOH G 7 . ? 12.833 62.008 -2.191 1.00 29.70 ? 5106 HOH A O 1 HETATM 8360 O O . HOH G 7 . ? 10.916 65.270 -5.249 1.00 33.83 ? 5107 HOH A O 1 HETATM 8361 O O . HOH G 7 . ? 13.170 66.674 -4.467 1.00 17.42 ? 5108 HOH A O 1 HETATM 8362 O O . HOH G 7 . ? 14.165 68.294 -7.540 1.00 18.86 ? 5109 HOH A O 1 HETATM 8363 O O . HOH G 7 . ? 13.649 69.960 -9.602 1.00 30.96 ? 5110 HOH A O 1 HETATM 8364 O O . HOH G 7 . ? 12.855 66.337 -9.245 1.00 23.82 ? 5111 HOH A O 1 HETATM 8365 O O . HOH G 7 . ? 12.232 64.436 -12.039 1.00 37.22 ? 5112 HOH A O 1 HETATM 8366 O O . HOH G 7 . ? 14.291 62.834 -11.770 1.00 22.50 ? 5113 HOH A O 1 HETATM 8367 O O . HOH G 7 . ? 14.639 61.980 -14.364 1.00 23.27 ? 5114 HOH A O 1 HETATM 8368 O O . HOH G 7 . ? 14.491 63.926 -16.138 1.00 18.41 ? 5115 HOH A O 1 HETATM 8369 O O . HOH G 7 . ? 11.907 63.565 -16.590 1.00 20.75 ? 5116 HOH A O 1 HETATM 8370 O O . HOH G 7 . ? 10.238 62.822 -14.604 1.00 34.50 ? 5117 HOH A O 1 HETATM 8371 O O . HOH G 7 . ? 11.562 61.295 -18.151 1.00 19.60 ? 5118 HOH A O 1 HETATM 8372 O O . HOH G 7 . ? 13.503 62.466 -19.634 1.00 21.83 ? 5119 HOH A O 1 HETATM 8373 O O . HOH G 7 . ? 13.895 60.834 -22.277 1.00 16.05 ? 5120 HOH A O 1 HETATM 8374 O O . HOH G 7 . ? 12.427 61.907 -23.910 1.00 38.20 ? 5121 HOH A O 1 HETATM 8375 O O . HOH G 7 . ? 14.954 63.697 -25.414 1.00 22.44 ? 5122 HOH A O 1 HETATM 8376 O O . HOH G 7 . ? 17.037 67.156 -25.765 1.00 29.98 ? 5123 HOH A O 1 HETATM 8377 O O . HOH G 7 . ? 18.544 65.104 -26.694 1.00 25.13 ? 5124 HOH A O 1 HETATM 8378 O O . HOH G 7 . ? 16.822 60.497 -27.979 1.00 19.73 ? 5125 HOH A O 1 HETATM 8379 O O . HOH G 7 . ? 20.362 58.787 -21.762 1.00 11.00 ? 5126 HOH A O 1 HETATM 8380 O O . HOH G 7 . ? 18.258 59.721 -19.848 1.00 17.35 ? 5127 HOH A O 1 HETATM 8381 O O . HOH G 7 . ? 20.625 66.166 -19.499 1.00 12.65 ? 5128 HOH A O 1 HETATM 8382 O O . HOH G 7 . ? 16.584 67.874 -19.477 1.00 19.38 ? 5129 HOH A O 1 HETATM 8383 O O . HOH G 7 . ? 14.693 70.203 -19.995 1.00 28.03 ? 5130 HOH A O 1 HETATM 8384 O O . HOH G 7 . ? 14.659 70.644 -22.532 1.00 32.05 ? 5131 HOH A O 1 HETATM 8385 O O . HOH G 7 . ? 17.465 70.140 -23.211 1.00 18.66 ? 5132 HOH A O 1 HETATM 8386 O O . HOH G 7 . ? 15.021 73.861 -21.277 1.00 39.18 ? 5133 HOH A O 1 HETATM 8387 O O . HOH G 7 . ? 16.223 75.136 -23.804 1.00 37.94 ? 5134 HOH A O 1 HETATM 8388 O O . HOH G 7 . ? 16.058 72.079 -18.842 1.00 17.56 ? 5135 HOH A O 1 HETATM 8389 O O . HOH G 7 . ? 17.210 70.220 -15.995 1.00 14.85 ? 5136 HOH A O 1 HETATM 8390 O O . HOH G 7 . ? 14.857 66.367 -14.999 1.00 19.87 ? 5137 HOH A O 1 HETATM 8391 O O . HOH G 7 . ? 11.188 73.627 -17.458 1.00 30.03 ? 5138 HOH A O 1 HETATM 8392 O O . HOH G 7 . ? 12.913 74.721 -18.681 1.00 37.78 ? 5139 HOH A O 1 HETATM 8393 O O . HOH G 7 . ? 12.049 75.192 -13.670 1.00 29.19 ? 5140 HOH A O 1 HETATM 8394 O O . HOH G 7 . ? 15.466 76.999 -13.407 1.00 29.01 ? 5141 HOH A O 1 HETATM 8395 O O . HOH G 7 . ? 15.936 75.129 -11.340 1.00 23.35 ? 5142 HOH A O 1 HETATM 8396 O O . HOH G 7 . ? 20.258 74.225 -6.472 1.00 15.16 ? 5143 HOH A O 1 HETATM 8397 O O . HOH G 7 . ? 17.028 74.405 -2.727 1.00 16.57 ? 5144 HOH A O 1 HETATM 8398 O O . HOH G 7 . ? 12.757 70.958 -0.359 1.00 27.46 ? 5145 HOH A O 1 HETATM 8399 O O . HOH G 7 . ? 13.252 68.605 1.305 1.00 21.56 ? 5146 HOH A O 1 HETATM 8400 O O . HOH G 7 . ? 18.524 69.760 4.522 1.00 13.40 ? 5147 HOH A O 1 HETATM 8401 O O . HOH G 7 . ? 19.298 72.133 3.439 1.00 17.61 ? 5148 HOH A O 1 HETATM 8402 O O . HOH G 7 . ? 17.757 74.252 3.966 1.00 23.43 ? 5149 HOH A O 1 HETATM 8403 O O . HOH G 7 . ? 19.123 76.331 5.043 1.00 24.24 ? 5150 HOH A O 1 HETATM 8404 O O . HOH G 7 . ? 21.193 79.466 5.468 1.00 38.44 ? 5151 HOH A O 1 HETATM 8405 O O . HOH G 7 . ? 22.031 76.541 8.957 1.00 23.07 ? 5152 HOH A O 1 HETATM 8406 O O . HOH G 7 . ? 25.097 73.796 9.114 1.00 20.15 ? 5153 HOH A O 1 HETATM 8407 O O . HOH G 7 . ? 25.198 74.706 11.525 1.00 38.64 ? 5154 HOH A O 1 HETATM 8408 O O . HOH G 7 . ? 29.469 75.806 11.372 1.00 40.07 ? 5155 HOH A O 1 HETATM 8409 O O . HOH G 7 . ? 29.589 71.940 12.867 1.00 19.28 ? 5156 HOH A O 1 HETATM 8410 O O . HOH G 7 . ? 31.819 71.357 14.070 1.00 31.88 ? 5157 HOH A O 1 HETATM 8411 O O . HOH G 7 . ? 30.128 69.206 15.515 1.00 34.75 ? 5158 HOH A O 1 HETATM 8412 O O . HOH G 7 . ? 33.541 68.492 16.879 1.00 37.99 ? 5159 HOH A O 1 HETATM 8413 O O . HOH G 7 . ? 35.971 70.574 16.670 1.00 41.10 ? 5160 HOH A O 1 HETATM 8414 O O . HOH G 7 . ? 35.782 70.076 19.291 1.00 30.91 ? 5161 HOH A O 1 HETATM 8415 O O . HOH G 7 . ? 34.719 70.254 13.468 1.00 22.71 ? 5162 HOH A O 1 HETATM 8416 O O . HOH G 7 . ? 34.111 67.444 12.609 1.00 12.55 ? 5163 HOH A O 1 HETATM 8417 O O . HOH G 7 . ? 28.623 63.250 11.040 1.00 22.22 ? 5164 HOH A O 1 HETATM 8418 O O . HOH G 7 . ? 28.466 62.679 13.729 1.00 34.44 ? 5165 HOH A O 1 HETATM 8419 O O . HOH G 7 . ? 25.796 62.901 13.574 1.00 25.51 ? 5166 HOH A O 1 HETATM 8420 O O . HOH G 7 . ? 24.407 63.012 11.846 1.00 30.28 ? 5167 HOH A O 1 HETATM 8421 O O . HOH G 7 . ? 22.246 65.033 12.079 1.00 33.63 ? 5168 HOH A O 1 HETATM 8422 O O . HOH G 7 . ? 22.071 63.797 14.210 1.00 31.47 ? 5169 HOH A O 1 HETATM 8423 O O . HOH G 7 . ? 22.837 66.047 14.359 1.00 32.86 ? 5170 HOH A O 1 HETATM 8424 O O . HOH G 7 . ? 25.696 65.768 17.451 1.00 30.59 ? 5171 HOH A O 1 HETATM 8425 O O . HOH G 7 . ? 26.388 63.351 17.116 1.00 17.84 ? 5172 HOH A O 1 HETATM 8426 O O . HOH G 7 . ? 22.992 63.987 18.617 1.00 30.16 ? 5173 HOH A O 1 HETATM 8427 O O . HOH G 7 . ? 22.576 62.267 16.222 1.00 19.62 ? 5174 HOH A O 1 HETATM 8428 O O . HOH G 7 . ? 27.940 60.640 19.549 1.00 11.54 ? 5175 HOH A O 1 HETATM 8429 O O . HOH G 7 . ? 28.568 64.746 19.884 1.00 16.47 ? 5176 HOH A O 1 HETATM 8430 O O . HOH G 7 . ? 26.269 66.125 20.252 1.00 23.12 ? 5177 HOH A O 1 HETATM 8431 O O . HOH G 7 . ? 25.454 70.581 26.842 1.00 37.17 ? 5178 HOH A O 1 HETATM 8432 O O . HOH G 7 . ? 23.282 68.913 28.895 1.00 35.51 ? 5179 HOH A O 1 HETATM 8433 O O . HOH G 7 . ? 27.823 67.240 28.392 1.00 23.02 ? 5180 HOH A O 1 HETATM 8434 O O . HOH G 7 . ? 28.884 63.852 30.190 1.00 26.10 ? 5181 HOH A O 1 HETATM 8435 O O . HOH G 7 . ? 29.794 64.777 32.814 1.00 40.39 ? 5182 HOH A O 1 HETATM 8436 O O . HOH G 7 . ? 35.179 61.736 34.364 1.00 23.91 ? 5183 HOH A O 1 HETATM 8437 O O . HOH G 7 . ? 37.523 61.843 35.646 1.00 40.76 ? 5184 HOH A O 1 HETATM 8438 O O . HOH G 7 . ? 40.969 66.155 34.906 1.00 40.51 ? 5185 HOH A O 1 HETATM 8439 O O . HOH G 7 . ? 39.679 66.529 31.702 1.00 29.19 ? 5186 HOH A O 1 HETATM 8440 O O . HOH G 7 . ? 42.026 67.047 29.519 1.00 23.24 ? 5187 HOH A O 1 HETATM 8441 O O . HOH G 7 . ? 44.494 67.583 28.505 1.00 35.86 ? 5188 HOH A O 1 HETATM 8442 O O . HOH G 7 . ? 46.376 68.188 26.693 1.00 28.97 ? 5189 HOH A O 1 HETATM 8443 O O . HOH G 7 . ? 47.712 65.844 27.134 1.00 39.14 ? 5190 HOH A O 1 HETATM 8444 O O . HOH G 7 . ? 48.677 67.910 25.087 1.00 46.34 ? 5191 HOH A O 1 HETATM 8445 O O . HOH G 7 . ? 51.881 63.797 24.627 1.00 31.53 ? 5192 HOH A O 1 HETATM 8446 O O . HOH G 7 . ? 50.728 61.689 26.741 1.00 21.43 ? 5193 HOH A O 1 HETATM 8447 O O . HOH G 7 . ? 56.908 64.751 24.304 1.00 26.59 ? 5194 HOH A O 1 HETATM 8448 O O . HOH G 7 . ? 59.418 61.667 25.899 1.00 27.50 ? 5195 HOH A O 1 HETATM 8449 O O . HOH G 7 . ? 62.455 61.963 25.885 1.00 35.77 ? 5196 HOH A O 1 HETATM 8450 O O . HOH G 7 . ? 59.341 54.978 27.202 1.00 26.82 ? 5197 HOH A O 1 HETATM 8451 O O . HOH G 7 . ? 57.929 52.263 26.544 1.00 31.98 ? 5198 HOH A O 1 HETATM 8452 O O . HOH G 7 . ? 55.998 51.642 27.480 1.00 24.28 ? 5199 HOH A O 1 HETATM 8453 O O . HOH G 7 . ? 56.138 52.949 29.997 1.00 32.03 ? 5200 HOH A O 1 HETATM 8454 O O . HOH G 7 . ? 53.330 52.222 26.473 1.00 18.75 ? 5201 HOH A O 1 HETATM 8455 O O . HOH G 7 . ? 51.910 50.275 27.807 1.00 31.40 ? 5202 HOH A O 1 HETATM 8456 O O . HOH G 7 . ? 52.466 49.011 25.995 1.00 36.86 ? 5203 HOH A O 1 HETATM 8457 O O . HOH G 7 . ? 49.378 49.778 28.335 1.00 16.33 ? 5204 HOH A O 1 HETATM 8458 O O . HOH G 7 . ? 50.133 47.209 29.240 1.00 19.45 ? 5205 HOH A O 1 HETATM 8459 O O . HOH G 7 . ? 49.674 45.339 31.059 1.00 23.24 ? 5206 HOH A O 1 HETATM 8460 O O . HOH G 7 . ? 49.434 50.332 32.799 1.00 28.03 ? 5207 HOH A O 1 HETATM 8461 O O . HOH G 7 . ? 48.274 50.366 35.198 1.00 25.08 ? 5208 HOH A O 1 HETATM 8462 O O . HOH G 7 . ? 42.718 53.039 35.640 1.00 24.12 ? 5209 HOH A O 1 HETATM 8463 O O . HOH G 7 . ? 44.403 55.089 36.394 1.00 38.34 ? 5210 HOH A O 1 HETATM 8464 O O . HOH G 7 . ? 43.540 56.266 33.838 1.00 25.53 ? 5211 HOH A O 1 HETATM 8465 O O . HOH G 7 . ? 39.785 52.135 36.323 1.00 28.72 ? 5212 HOH A O 1 HETATM 8466 O O . HOH G 7 . ? 40.214 49.242 35.812 1.00 31.48 ? 5213 HOH A O 1 HETATM 8467 O O . HOH G 7 . ? 41.605 50.143 33.919 1.00 37.60 ? 5214 HOH A O 1 HETATM 8468 O O . HOH G 7 . ? 37.520 46.513 29.869 1.00 25.18 ? 5215 HOH A O 1 HETATM 8469 O O . HOH G 7 . ? 37.067 45.229 27.603 1.00 16.53 ? 5216 HOH A O 1 HETATM 8470 O O . HOH G 7 . ? 39.916 44.871 26.425 1.00 27.23 ? 5217 HOH A O 1 HETATM 8471 O O . HOH G 7 . ? 39.199 42.628 23.100 1.00 27.29 ? 5218 HOH A O 1 HETATM 8472 O O . HOH G 7 . ? 39.752 39.190 20.329 1.00 28.83 ? 5219 HOH A O 1 HETATM 8473 O O . HOH G 7 . ? 38.236 38.265 22.022 1.00 27.66 ? 5220 HOH A O 1 HETATM 8474 O O . HOH G 7 . ? 38.125 36.849 24.098 1.00 45.91 ? 5221 HOH A O 1 HETATM 8475 O O . HOH G 7 . ? 37.030 38.554 25.855 1.00 34.21 ? 5222 HOH A O 1 HETATM 8476 O O . HOH G 7 . ? 34.915 35.391 23.652 1.00 37.09 ? 5223 HOH A O 1 HETATM 8477 O O . HOH G 7 . ? 32.450 34.256 24.216 1.00 32.63 ? 5224 HOH A O 1 HETATM 8478 O O . HOH G 7 . ? 29.381 30.901 21.923 1.00 34.59 ? 5225 HOH A O 1 HETATM 8479 O O . HOH G 7 . ? 29.386 29.528 24.592 1.00 40.52 ? 5226 HOH A O 1 HETATM 8480 O O . HOH G 7 . ? 26.125 32.513 28.872 1.00 22.23 ? 5227 HOH A O 1 HETATM 8481 O O . HOH G 7 . ? 27.123 34.700 29.636 1.00 23.48 ? 5228 HOH A O 1 HETATM 8482 O O . HOH G 7 . ? 26.088 37.233 29.400 1.00 15.70 ? 5229 HOH A O 1 HETATM 8483 O O . HOH G 7 . ? 30.062 36.154 29.160 1.00 23.00 ? 5230 HOH A O 1 HETATM 8484 O O . HOH G 7 . ? 35.057 43.120 28.910 1.00 13.47 ? 5231 HOH A O 1 HETATM 8485 O O . HOH G 7 . ? 35.691 44.825 30.990 1.00 22.32 ? 5232 HOH A O 1 HETATM 8486 O O . HOH G 7 . ? 34.498 45.431 33.354 1.00 22.41 ? 5233 HOH A O 1 HETATM 8487 O O . HOH G 7 . ? 35.874 44.457 35.992 1.00 37.96 ? 5234 HOH A O 1 HETATM 8488 O O . HOH G 7 . ? 34.323 47.580 36.676 1.00 44.00 ? 5235 HOH A O 1 HETATM 8489 O O . HOH G 7 . ? 34.169 50.693 36.298 1.00 38.13 ? 5236 HOH A O 1 HETATM 8490 O O . HOH G 7 . ? 29.748 50.962 39.801 1.00 31.58 ? 5237 HOH A O 1 HETATM 8491 O O . HOH G 7 . ? 27.691 49.269 38.488 1.00 25.02 ? 5238 HOH A O 1 HETATM 8492 O O . HOH G 7 . ? 28.834 46.796 37.315 1.00 24.32 ? 5239 HOH A O 1 HETATM 8493 O O . HOH G 7 . ? 27.470 51.890 42.662 1.00 27.33 ? 5240 HOH A O 1 HETATM 8494 O O . HOH G 7 . ? 28.727 54.992 40.066 1.00 33.61 ? 5241 HOH A O 1 HETATM 8495 O O . HOH G 7 . ? 31.438 57.255 37.472 1.00 29.29 ? 5242 HOH A O 1 HETATM 8496 O O . HOH G 7 . ? 30.024 58.848 35.444 1.00 25.69 ? 5243 HOH A O 1 HETATM 8497 O O . HOH G 7 . ? 23.620 57.012 38.740 1.00 29.65 ? 5244 HOH A O 1 HETATM 8498 O O . HOH G 7 . ? 21.529 55.063 40.252 1.00 32.04 ? 5245 HOH A O 1 HETATM 8499 O O . HOH G 7 . ? 17.576 50.452 37.907 1.00 30.25 ? 5246 HOH A O 1 HETATM 8500 O O . HOH G 7 . ? 18.659 48.483 37.618 1.00 20.75 ? 5247 HOH A O 1 HETATM 8501 O O . HOH G 7 . ? 20.966 46.975 39.080 1.00 24.64 ? 5248 HOH A O 1 HETATM 8502 O O . HOH G 7 . ? 18.508 46.166 40.178 1.00 31.62 ? 5249 HOH A O 1 HETATM 8503 O O . HOH G 7 . ? 15.431 51.442 36.451 1.00 33.56 ? 5250 HOH A O 1 HETATM 8504 O O . HOH G 7 . ? 17.648 52.259 35.742 1.00 29.25 ? 5251 HOH A O 1 HETATM 8505 O O . HOH G 7 . ? 14.383 46.559 32.559 1.00 23.08 ? 5252 HOH A O 1 HETATM 8506 O O . HOH G 7 . ? 12.367 46.485 30.971 1.00 34.47 ? 5253 HOH A O 1 HETATM 8507 O O . HOH G 7 . ? 11.966 43.526 26.370 1.00 39.57 ? 5254 HOH A O 1 HETATM 8508 O O . HOH G 7 . ? 10.861 46.154 21.202 1.00 27.62 ? 5255 HOH A O 1 HETATM 8509 O O . HOH G 7 . ? 11.510 46.466 17.894 1.00 26.07 ? 5256 HOH A O 1 HETATM 8510 O O . HOH G 7 . ? 12.372 49.213 17.956 1.00 18.49 ? 5257 HOH A O 1 HETATM 8511 O O . HOH G 7 . ? 10.211 50.207 18.944 1.00 24.51 ? 5258 HOH A O 1 HETATM 8512 O O . HOH G 7 . ? 10.658 51.211 21.409 1.00 19.73 ? 5259 HOH A O 1 HETATM 8513 O O . HOH G 7 . ? 13.303 51.154 21.789 1.00 16.67 ? 5260 HOH A O 1 HETATM 8514 O O . HOH G 7 . ? 14.163 49.470 19.794 1.00 15.43 ? 5261 HOH A O 1 HETATM 8515 O O . HOH G 7 . ? 13.961 48.693 15.425 1.00 14.55 ? 5262 HOH A O 1 HETATM 8516 O O . HOH G 7 . ? 11.768 51.153 14.392 1.00 14.47 ? 5263 HOH A O 1 HETATM 8517 O O . HOH G 7 . ? 9.281 52.075 16.906 1.00 17.43 ? 5264 HOH A O 1 HETATM 8518 O O . HOH G 7 . ? 8.131 48.251 19.480 1.00 30.42 ? 5265 HOH A O 1 HETATM 8519 O O . HOH G 7 . ? 6.078 46.101 16.495 1.00 36.02 ? 5266 HOH A O 1 HETATM 8520 O O . HOH G 7 . ? 6.423 46.672 13.321 1.00 32.78 ? 5267 HOH A O 1 HETATM 8521 O O . HOH G 7 . ? 7.884 47.968 11.902 1.00 24.05 ? 5268 HOH A O 1 HETATM 8522 O O . HOH G 7 . ? 8.619 44.263 12.961 1.00 26.21 ? 5269 HOH A O 1 HETATM 8523 O O . HOH G 7 . ? 10.293 41.462 11.841 1.00 36.05 ? 5270 HOH A O 1 HETATM 8524 O O . HOH G 7 . ? 12.861 42.155 12.521 1.00 19.97 ? 5271 HOH A O 1 HETATM 8525 O O . HOH G 7 . ? 14.925 39.804 12.472 1.00 42.23 ? 5272 HOH A O 1 HETATM 8526 O O . HOH G 7 . ? 17.196 41.205 9.335 1.00 30.87 ? 5273 HOH A O 1 HETATM 8527 O O . HOH G 7 . ? 19.232 35.834 5.320 1.00 38.38 ? 5274 HOH A O 1 HETATM 8528 O O . HOH G 7 . ? 25.930 39.618 5.253 1.00 8.49 ? 5275 HOH A O 1 HETATM 8529 O O . HOH G 7 . ? 26.313 39.805 8.003 1.00 11.06 ? 5276 HOH A O 1 HETATM 8530 O O . HOH G 7 . ? 24.110 41.722 6.933 1.00 9.48 ? 5277 HOH A O 1 HETATM 8531 O O . HOH G 7 . ? 28.182 39.349 11.308 1.00 8.80 ? 5278 HOH A O 1 HETATM 8532 O O . HOH G 7 . ? 27.214 41.073 13.405 1.00 14.62 ? 5279 HOH A O 1 HETATM 8533 O O . HOH G 7 . ? 25.081 39.674 14.285 1.00 16.65 ? 5280 HOH A O 1 HETATM 8534 O O . HOH G 7 . ? 28.362 43.565 13.289 1.00 8.50 ? 5281 HOH A O 1 HETATM 8535 O O . HOH G 7 . ? 27.261 46.024 13.730 1.00 12.81 ? 5282 HOH A O 1 HETATM 8536 O O . HOH G 7 . ? 27.864 48.176 12.223 1.00 12.58 ? 5283 HOH A O 1 HETATM 8537 O O . HOH G 7 . ? 27.480 50.667 13.340 1.00 18.51 ? 5284 HOH A O 1 HETATM 8538 O O . HOH G 7 . ? 25.529 52.024 12.918 1.00 17.94 ? 5285 HOH A O 1 HETATM 8539 O O . HOH G 7 . ? 25.509 53.487 11.157 1.00 9.73 ? 5286 HOH A O 1 HETATM 8540 O O . HOH G 7 . ? 19.309 54.820 11.612 1.00 11.17 ? 5287 HOH A O 1 HETATM 8541 O O . HOH G 7 . ? 16.974 56.000 10.481 1.00 13.00 ? 5288 HOH A O 1 HETATM 8542 O O . HOH G 7 . ? 16.722 56.857 13.091 1.00 15.68 ? 5289 HOH A O 1 HETATM 8543 O O . HOH G 7 . ? 18.340 54.634 14.336 1.00 11.44 ? 5290 HOH A O 1 HETATM 8544 O O . HOH G 7 . ? 20.109 54.441 16.257 1.00 11.08 ? 5291 HOH A O 1 HETATM 8545 O O . HOH G 7 . ? 13.982 57.875 16.331 1.00 17.40 ? 5292 HOH A O 1 HETATM 8546 O O . HOH G 7 . ? 11.407 58.479 16.968 1.00 33.43 ? 5293 HOH A O 1 HETATM 8547 O O . HOH G 7 . ? 11.402 58.089 20.055 1.00 26.73 ? 5294 HOH A O 1 HETATM 8548 O O . HOH G 7 . ? 10.803 56.404 21.766 1.00 39.05 ? 5295 HOH A O 1 HETATM 8549 O O . HOH G 7 . ? 12.169 54.763 22.593 1.00 24.70 ? 5296 HOH A O 1 HETATM 8550 O O . HOH G 7 . ? 9.591 53.542 22.383 1.00 32.31 ? 5297 HOH A O 1 HETATM 8551 O O . HOH G 7 . ? 13.936 57.416 19.167 1.00 18.76 ? 5298 HOH A O 1 HETATM 8552 O O . HOH G 7 . ? 15.497 60.045 15.604 1.00 14.57 ? 5299 HOH A O 1 HETATM 8553 O O . HOH G 7 . ? 13.838 62.042 14.630 1.00 27.16 ? 5300 HOH A O 1 HETATM 8554 O O . HOH G 7 . ? 13.150 62.373 11.962 1.00 23.90 ? 5301 HOH A O 1 HETATM 8555 O O . HOH G 7 . ? 13.775 60.645 7.816 1.00 30.67 ? 5302 HOH A O 1 HETATM 8556 O O . HOH G 7 . ? 14.388 59.860 5.337 1.00 11.68 ? 5303 HOH A O 1 HETATM 8557 O O . HOH G 7 . ? 11.455 62.051 5.660 1.00 36.46 ? 5304 HOH A O 1 HETATM 8558 O O . HOH G 7 . ? 9.778 59.642 7.284 1.00 45.62 ? 5305 HOH A O 1 HETATM 8559 O O . HOH G 7 . ? 11.710 58.603 8.090 1.00 21.67 ? 5306 HOH A O 1 HETATM 8560 O O . HOH G 7 . ? 12.468 56.038 5.452 1.00 15.72 ? 5307 HOH A O 1 HETATM 8561 O O . HOH G 7 . ? 11.387 52.811 6.965 1.00 16.20 ? 5308 HOH A O 1 HETATM 8562 O O . HOH G 7 . ? 9.048 50.156 7.940 1.00 22.83 ? 5309 HOH A O 1 HETATM 8563 O O . HOH G 7 . ? 5.358 57.715 7.083 1.00 25.67 ? 5310 HOH A O 1 HETATM 8564 O O . HOH G 7 . ? 7.382 58.111 0.490 1.00 36.89 ? 5311 HOH A O 1 HETATM 8565 O O . HOH G 7 . ? 10.400 61.952 2.081 1.00 27.40 ? 5312 HOH A O 1 HETATM 8566 O O . HOH G 7 . ? 13.982 64.403 6.963 1.00 35.91 ? 5313 HOH A O 1 HETATM 8567 O O . HOH G 7 . ? 20.767 65.193 7.827 1.00 15.74 ? 5314 HOH A O 1 HETATM 8568 O O . HOH G 7 . ? 20.379 67.992 8.527 1.00 20.78 ? 5315 HOH A O 1 HETATM 8569 O O . HOH G 7 . ? 17.630 71.051 6.866 1.00 30.07 ? 5316 HOH A O 1 HETATM 8570 O O . HOH G 7 . ? 15.618 73.212 5.793 1.00 32.08 ? 5317 HOH A O 1 HETATM 8571 O O . HOH G 7 . ? 19.628 80.276 -0.401 1.00 26.88 ? 5318 HOH A O 1 HETATM 8572 O O . HOH G 7 . ? 21.564 78.328 -0.980 1.00 19.90 ? 5319 HOH A O 1 HETATM 8573 O O . HOH G 7 . ? 26.556 74.604 2.712 1.00 21.31 ? 5320 HOH A O 1 HETATM 8574 O O . HOH G 7 . ? 26.028 72.475 5.992 1.00 12.02 ? 5321 HOH A O 1 HETATM 8575 O O . HOH G 7 . ? 28.051 82.086 6.965 1.00 29.92 ? 5322 HOH A O 1 HETATM 8576 O O . HOH G 7 . ? 27.628 82.185 3.801 1.00 35.78 ? 5323 HOH A O 1 HETATM 8577 O O . HOH G 7 . ? 29.998 82.640 2.775 1.00 25.58 ? 5324 HOH A O 1 HETATM 8578 O O . HOH G 7 . ? 31.460 81.590 0.841 1.00 23.95 ? 5325 HOH A O 1 HETATM 8579 O O . HOH G 7 . ? 33.221 83.286 1.928 1.00 42.77 ? 5326 HOH A O 1 HETATM 8580 O O . HOH G 7 . ? 37.940 83.154 -0.340 1.00 22.33 ? 5327 HOH A O 1 HETATM 8581 O O . HOH G 7 . ? 37.647 80.492 -0.122 1.00 20.33 ? 5328 HOH A O 1 HETATM 8582 O O . HOH G 7 . ? 38.564 80.162 -2.537 1.00 30.69 ? 5329 HOH A O 1 HETATM 8583 O O . HOH G 7 . ? 36.484 79.050 -4.769 1.00 19.28 ? 5330 HOH A O 1 HETATM 8584 O O . HOH G 7 . ? 35.876 77.496 -6.981 1.00 15.47 ? 5331 HOH A O 1 HETATM 8585 O O . HOH G 7 . ? 34.672 78.965 -8.783 1.00 13.66 ? 5332 HOH A O 1 HETATM 8586 O O . HOH G 7 . ? 32.860 80.956 -11.428 1.00 10.98 ? 5333 HOH A O 1 HETATM 8587 O O . HOH G 7 . ? 33.695 83.553 -10.143 1.00 18.50 ? 5334 HOH A O 1 HETATM 8588 O O . HOH G 7 . ? 32.147 85.208 -8.234 1.00 25.39 ? 5335 HOH A O 1 HETATM 8589 O O . HOH G 7 . ? 32.889 85.234 -5.281 1.00 21.86 ? 5336 HOH A O 1 HETATM 8590 O O . HOH G 7 . ? 35.860 85.795 -7.481 1.00 35.88 ? 5337 HOH A O 1 HETATM 8591 O O . HOH G 7 . ? 34.214 87.098 -9.857 1.00 38.96 ? 5338 HOH A O 1 HETATM 8592 O O . HOH G 7 . ? 32.560 88.954 -13.367 1.00 31.93 ? 5339 HOH A O 1 HETATM 8593 O O . HOH G 7 . ? 30.524 87.218 -14.618 1.00 26.98 ? 5340 HOH A O 1 HETATM 8594 O O . HOH G 7 . ? 28.091 85.956 -14.228 1.00 36.08 ? 5341 HOH A O 1 HETATM 8595 O O . HOH G 7 . ? 29.544 87.367 -17.240 1.00 27.52 ? 5342 HOH A O 1 HETATM 8596 O O . HOH G 7 . ? 31.718 85.831 -19.543 1.00 19.26 ? 5343 HOH A O 1 HETATM 8597 O O . HOH G 7 . ? 33.361 84.296 -17.953 1.00 20.24 ? 5344 HOH A O 1 HETATM 8598 O O . HOH G 7 . ? 35.595 86.616 -17.654 1.00 36.28 ? 5345 HOH A O 1 HETATM 8599 O O . HOH G 7 . ? 40.386 86.655 -20.760 1.00 30.62 ? 5346 HOH A O 1 HETATM 8600 O O . HOH G 7 . ? 39.847 81.834 -21.623 1.00 28.41 ? 5347 HOH A O 1 HETATM 8601 O O . HOH G 7 . ? 42.303 79.646 -23.052 1.00 30.72 ? 5348 HOH A O 1 HETATM 8602 O O . HOH G 7 . ? 44.071 79.039 -20.791 1.00 29.74 ? 5349 HOH A O 1 HETATM 8603 O O . HOH G 7 . ? 47.071 80.649 -21.578 1.00 28.69 ? 5350 HOH A O 1 HETATM 8604 O O . HOH G 7 . ? 46.408 80.409 -24.959 1.00 39.76 ? 5351 HOH A O 1 HETATM 8605 O O . HOH G 7 . ? 45.821 82.873 -24.791 1.00 34.15 ? 5352 HOH A O 1 HETATM 8606 O O . HOH G 7 . ? 44.438 83.700 -27.568 1.00 30.00 ? 5353 HOH A O 1 HETATM 8607 O O . HOH G 7 . ? 44.900 82.683 -29.970 1.00 33.10 ? 5354 HOH A O 1 HETATM 8608 O O . HOH G 7 . ? 42.724 80.534 -31.751 1.00 47.52 ? 5355 HOH A O 1 HETATM 8609 O O . HOH G 7 . ? 44.761 79.299 -33.049 1.00 30.99 ? 5356 HOH A O 1 HETATM 8610 O O . HOH G 7 . ? 42.552 78.660 -29.746 1.00 29.43 ? 5357 HOH A O 1 HETATM 8611 O O . HOH G 7 . ? 43.084 79.861 -27.486 1.00 40.48 ? 5358 HOH A O 1 HETATM 8612 O O . HOH G 7 . ? 40.403 79.354 -28.079 1.00 28.65 ? 5359 HOH A O 1 HETATM 8613 O O . HOH G 7 . ? 41.343 82.966 -28.631 1.00 33.58 ? 5360 HOH A O 1 HETATM 8614 O O . HOH G 7 . ? 40.733 82.813 -31.065 1.00 32.48 ? 5361 HOH A O 1 HETATM 8615 O O . HOH G 7 . ? 38.275 81.732 -31.143 1.00 14.56 ? 5362 HOH A O 1 HETATM 8616 O O . HOH G 7 . ? 39.315 83.343 -27.070 1.00 22.57 ? 5363 HOH A O 1 HETATM 8617 O O . HOH G 7 . ? 46.452 77.785 -25.548 1.00 28.16 ? 5364 HOH A O 1 HETATM 8618 O O . HOH G 7 . ? 48.110 74.635 -28.514 1.00 32.32 ? 5365 HOH A O 1 HETATM 8619 O O . HOH G 7 . ? 48.696 72.263 -25.994 1.00 33.78 ? 5366 HOH A O 1 HETATM 8620 O O . HOH G 7 . ? 47.186 72.931 -24.307 1.00 34.45 ? 5367 HOH A O 1 HETATM 8621 O O . HOH G 7 . ? 50.514 73.580 -24.964 1.00 37.23 ? 5368 HOH A O 1 HETATM 8622 O O . HOH G 7 . ? 51.151 70.808 -23.318 1.00 18.98 ? 5369 HOH A O 1 HETATM 8623 O O . HOH G 7 . ? 50.053 73.263 -21.451 1.00 20.28 ? 5370 HOH A O 1 HETATM 8624 O O . HOH G 7 . ? 51.449 71.389 -20.012 1.00 21.76 ? 5371 HOH A O 1 HETATM 8625 O O . HOH G 7 . ? 53.752 72.656 -19.006 1.00 14.87 ? 5372 HOH A O 1 HETATM 8626 O O . HOH G 7 . ? 53.235 70.826 -16.740 1.00 27.62 ? 5373 HOH A O 1 HETATM 8627 O O . HOH G 7 . ? 50.146 70.828 -17.468 1.00 29.48 ? 5374 HOH A O 1 HETATM 8628 O O . HOH G 7 . ? 47.668 70.081 -16.592 1.00 25.01 ? 5375 HOH A O 1 HETATM 8629 O O . HOH G 7 . ? 45.341 69.510 -17.338 1.00 27.87 ? 5376 HOH A O 1 HETATM 8630 O O . HOH G 7 . ? 46.452 67.657 -15.383 1.00 13.40 ? 5377 HOH A O 1 HETATM 8631 O O . HOH G 7 . ? 47.165 72.462 -17.357 1.00 26.55 ? 5378 HOH A O 1 HETATM 8632 O O . HOH G 7 . ? 47.573 71.787 -20.106 1.00 22.47 ? 5379 HOH A O 1 HETATM 8633 O O . HOH G 7 . ? 47.763 67.403 -25.070 1.00 26.42 ? 5380 HOH A O 1 HETATM 8634 O O . HOH G 7 . ? 48.030 64.031 -25.510 1.00 24.38 ? 5381 HOH A O 1 HETATM 8635 O O . HOH G 7 . ? 46.637 61.784 -25.779 1.00 17.39 ? 5382 HOH A O 1 HETATM 8636 O O . HOH G 7 . ? 48.072 59.365 -25.417 1.00 13.66 ? 5383 HOH A O 1 HETATM 8637 O O . HOH G 7 . ? 49.539 59.324 -28.307 1.00 19.03 ? 5384 HOH A O 1 HETATM 8638 O O . HOH G 7 . ? 50.459 58.517 -30.684 1.00 30.56 ? 5385 HOH A O 1 HETATM 8639 O O . HOH G 7 . ? 50.516 60.979 -30.621 1.00 22.40 ? 5386 HOH A O 1 HETATM 8640 O O . HOH G 7 . ? 48.310 64.412 -28.380 1.00 21.19 ? 5387 HOH A O 1 HETATM 8641 O O . HOH G 7 . ? 47.461 68.083 -30.572 1.00 20.20 ? 5388 HOH A O 1 HETATM 8642 O O . HOH G 7 . ? 48.620 66.698 -33.424 1.00 36.45 ? 5389 HOH A O 1 HETATM 8643 O O . HOH G 7 . ? 48.961 69.215 -36.546 1.00 30.48 ? 5390 HOH A O 1 HETATM 8644 O O . HOH G 7 . ? 46.638 70.332 -36.386 1.00 21.00 ? 5391 HOH A O 1 HETATM 8645 O O . HOH G 7 . ? 46.298 70.320 -39.416 1.00 29.79 ? 5392 HOH A O 1 HETATM 8646 O O . HOH G 7 . ? 44.012 72.655 -41.693 1.00 18.91 ? 5393 HOH A O 1 HETATM 8647 O O . HOH G 7 . ? 42.392 74.698 -41.520 1.00 28.89 ? 5394 HOH A O 1 HETATM 8648 O O . HOH G 7 . ? 39.849 75.471 -39.915 1.00 23.93 ? 5395 HOH A O 1 HETATM 8649 O O . HOH G 7 . ? 37.826 75.687 -42.171 1.00 22.47 ? 5396 HOH A O 1 HETATM 8650 O O . HOH G 7 . ? 35.981 77.433 -42.689 1.00 35.63 ? 5397 HOH A O 1 HETATM 8651 O O . HOH G 7 . ? 31.268 79.003 -42.626 1.00 26.19 ? 5398 HOH A O 1 HETATM 8652 O O . HOH G 7 . ? 30.253 81.660 -42.967 1.00 31.74 ? 5399 HOH A O 1 HETATM 8653 O O . HOH G 7 . ? 34.160 86.944 -43.121 1.00 42.27 ? 5400 HOH A O 1 HETATM 8654 O O . HOH G 7 . ? 32.510 89.081 -42.809 1.00 24.07 ? 5401 HOH A O 1 HETATM 8655 O O . HOH G 7 . ? 28.292 90.646 -42.554 1.00 24.63 ? 5402 HOH A O 1 HETATM 8656 O O . HOH G 7 . ? 28.090 88.088 -41.323 1.00 24.44 ? 5403 HOH A O 1 HETATM 8657 O O . HOH G 7 . ? 25.799 87.717 -42.745 1.00 28.53 ? 5404 HOH A O 1 HETATM 8658 O O . HOH G 7 . ? 23.679 86.085 -40.596 1.00 36.50 ? 5405 HOH A O 1 HETATM 8659 O O . HOH G 7 . ? 23.183 88.319 -38.158 1.00 34.38 ? 5406 HOH A O 1 HETATM 8660 O O . HOH G 7 . ? 23.445 82.511 -40.374 1.00 20.86 ? 5407 HOH A O 1 HETATM 8661 O O . HOH G 7 . ? 22.249 80.489 -42.101 1.00 30.36 ? 5408 HOH A O 1 HETATM 8662 O O . HOH G 7 . ? 22.151 80.506 -35.667 1.00 27.01 ? 5409 HOH A O 1 HETATM 8663 O O . HOH G 7 . ? 20.667 80.488 -33.389 1.00 38.61 ? 5410 HOH A O 1 HETATM 8664 O O . HOH G 7 . ? 22.879 78.587 -30.380 1.00 23.40 ? 5411 HOH A O 1 HETATM 8665 O O . HOH G 7 . ? 22.538 77.398 -27.013 1.00 36.27 ? 5412 HOH A O 1 HETATM 8666 O O . HOH G 7 . ? 23.255 78.502 -24.461 1.00 21.62 ? 5413 HOH A O 1 HETATM 8667 O O . HOH G 7 . ? 21.034 79.332 -23.313 1.00 25.29 ? 5414 HOH A O 1 HETATM 8668 O O . HOH G 7 . ? 19.323 83.310 -25.696 1.00 35.18 ? 5415 HOH A O 1 HETATM 8669 O O . HOH G 7 . ? 18.828 86.474 -24.952 1.00 42.05 ? 5416 HOH A O 1 HETATM 8670 O O . HOH G 7 . ? 16.828 84.822 -23.555 1.00 42.49 ? 5417 HOH A O 1 HETATM 8671 O O . HOH G 7 . ? 19.985 84.212 -18.385 1.00 29.68 ? 5418 HOH A O 1 HETATM 8672 O O . HOH G 7 . ? 21.695 86.005 -18.722 1.00 48.20 ? 5419 HOH A O 1 HETATM 8673 O O . HOH G 7 . ? 18.789 83.778 -15.876 1.00 33.59 ? 5420 HOH A O 1 HETATM 8674 O O . HOH G 7 . ? 17.599 81.385 -16.391 1.00 32.29 ? 5421 HOH A O 1 HETATM 8675 O O . HOH G 7 . ? 18.545 82.125 -10.949 1.00 41.96 ? 5422 HOH A O 1 HETATM 8676 O O . HOH G 7 . ? 17.455 80.779 -7.112 1.00 18.31 ? 5423 HOH A O 1 HETATM 8677 O O . HOH G 7 . ? 10.594 77.073 -4.253 1.00 36.90 ? 5424 HOH A O 1 HETATM 8678 O O . HOH G 7 . ? 13.230 83.108 2.665 1.00 40.31 ? 5425 HOH A O 1 HETATM 8679 O O . HOH G 7 . ? 16.153 83.158 2.828 1.00 42.05 ? 5426 HOH A O 1 HETATM 8680 O O . HOH G 7 . ? 25.170 83.520 3.749 1.00 34.23 ? 5427 HOH A O 1 HETATM 8681 O O . HOH G 7 . ? 24.886 86.977 -0.690 1.00 39.10 ? 5428 HOH A O 1 HETATM 8682 O O . HOH G 7 . ? 27.957 88.652 -11.528 1.00 38.56 ? 5429 HOH A O 1 HETATM 8683 O O . HOH G 7 . ? 25.096 83.269 -16.466 1.00 25.32 ? 5430 HOH A O 1 HETATM 8684 O O . HOH G 7 . ? 26.980 87.608 -23.616 1.00 29.29 ? 5431 HOH A O 1 HETATM 8685 O O . HOH G 7 . ? 29.628 88.627 -26.020 1.00 16.71 ? 5432 HOH A O 1 HETATM 8686 O O . HOH G 7 . ? 28.222 90.835 -25.168 1.00 25.51 ? 5433 HOH A O 1 HETATM 8687 O O . HOH G 7 . ? 26.577 91.546 -27.422 1.00 27.63 ? 5434 HOH A O 1 HETATM 8688 O O . HOH G 7 . ? 23.909 90.832 -25.718 1.00 39.00 ? 5435 HOH A O 1 HETATM 8689 O O . HOH G 7 . ? 26.040 91.632 -31.827 1.00 34.20 ? 5436 HOH A O 1 HETATM 8690 O O . HOH G 7 . ? 27.332 89.710 -31.573 1.00 35.19 ? 5437 HOH A O 1 HETATM 8691 O O . HOH G 7 . ? 25.625 85.995 -31.620 1.00 21.87 ? 5438 HOH A O 1 HETATM 8692 O O . HOH G 7 . ? 23.509 86.986 -32.078 1.00 32.67 ? 5439 HOH A O 1 HETATM 8693 O O . HOH G 7 . ? 21.949 85.229 -31.137 1.00 55.36 ? 5440 HOH A O 1 HETATM 8694 O O . HOH G 7 . ? 28.168 84.508 -35.234 1.00 15.61 ? 5441 HOH A O 1 HETATM 8695 O O . HOH G 7 . ? 28.929 81.867 -35.461 1.00 20.12 ? 5442 HOH A O 1 HETATM 8696 O O . HOH G 7 . ? 32.433 77.600 -29.521 1.00 16.32 ? 5443 HOH A O 1 HETATM 8697 O O . HOH G 7 . ? 30.415 74.983 -29.056 1.00 17.72 ? 5444 HOH A O 1 HETATM 8698 O O . HOH G 7 . ? 34.214 64.653 -32.052 1.00 19.13 ? 5445 HOH A O 1 HETATM 8699 O O . HOH G 7 . ? 36.084 63.408 -33.407 1.00 25.63 ? 5446 HOH A O 1 HETATM 8700 O O . HOH G 7 . ? 37.681 61.539 -32.531 1.00 28.00 ? 5447 HOH A O 1 HETATM 8701 O O . HOH G 7 . ? 37.070 59.284 -33.491 1.00 25.87 ? 5448 HOH A O 1 HETATM 8702 O O . HOH G 7 . ? 34.943 59.617 -34.808 1.00 28.15 ? 5449 HOH A O 1 HETATM 8703 O O . HOH G 7 . ? 33.772 57.282 -35.798 1.00 19.38 ? 5450 HOH A O 1 HETATM 8704 O O . HOH G 7 . ? 35.375 55.362 -34.235 1.00 38.19 ? 5451 HOH A O 1 HETATM 8705 O O . HOH G 7 . ? 36.676 56.884 -32.208 1.00 35.08 ? 5452 HOH A O 1 HETATM 8706 O O . HOH G 7 . ? 38.762 55.276 -31.418 1.00 18.61 ? 5453 HOH A O 1 HETATM 8707 O O . HOH G 7 . ? 40.827 56.183 -33.241 1.00 26.79 ? 5454 HOH A O 1 HETATM 8708 O O . HOH G 7 . ? 43.117 57.035 -31.542 1.00 27.38 ? 5455 HOH A O 1 HETATM 8709 O O . HOH G 7 . ? 43.122 59.740 -31.381 1.00 33.64 ? 5456 HOH A O 1 HETATM 8710 O O . HOH G 7 . ? 41.775 61.469 -29.403 1.00 23.27 ? 5457 HOH A O 1 HETATM 8711 O O . HOH G 7 . ? 44.007 63.065 -28.360 1.00 35.76 ? 5458 HOH A O 1 HETATM 8712 O O . HOH G 7 . ? 43.616 64.213 -31.187 1.00 45.49 ? 5459 HOH A O 1 HETATM 8713 O O . HOH G 7 . ? 43.737 66.627 -31.852 1.00 20.71 ? 5460 HOH A O 1 HETATM 8714 O O . HOH G 7 . ? 41.351 68.236 -32.527 1.00 18.40 ? 5461 HOH A O 1 HETATM 8715 O O . HOH G 7 . ? 39.472 69.383 -35.277 1.00 19.64 ? 5462 HOH A O 1 HETATM 8716 O O . HOH G 7 . ? 38.718 69.212 -38.058 1.00 18.58 ? 5463 HOH A O 1 HETATM 8717 O O . HOH G 7 . ? 40.778 71.616 -43.810 1.00 33.96 ? 5464 HOH A O 1 HETATM 8718 O O . HOH G 7 . ? 44.230 77.484 -43.319 1.00 39.89 ? 5465 HOH A O 1 HETATM 8719 O O . HOH G 7 . ? 46.784 80.131 -42.397 1.00 34.79 ? 5466 HOH A O 1 HETATM 8720 O O . HOH G 7 . ? 47.526 79.068 -40.235 1.00 19.70 ? 5467 HOH A O 1 HETATM 8721 O O . HOH G 7 . ? 51.563 76.293 -40.638 1.00 23.79 ? 5468 HOH A O 1 HETATM 8722 O O . HOH G 7 . ? 52.030 70.273 -37.866 1.00 23.44 ? 5469 HOH A O 1 HETATM 8723 O O . HOH G 7 . ? 54.208 71.241 -36.667 1.00 13.77 ? 5470 HOH A O 1 HETATM 8724 O O . HOH G 7 . ? 55.485 68.967 -37.362 1.00 30.74 ? 5471 HOH A O 1 HETATM 8725 O O . HOH G 7 . ? 56.655 70.163 -39.289 1.00 31.03 ? 5472 HOH A O 1 HETATM 8726 O O . HOH G 7 . ? 56.896 67.614 -35.280 1.00 30.97 ? 5473 HOH A O 1 HETATM 8727 O O . HOH G 7 . ? 56.404 65.222 -35.975 1.00 22.87 ? 5474 HOH A O 1 HETATM 8728 O O . HOH G 7 . ? 59.518 67.128 -34.358 1.00 28.69 ? 5475 HOH A O 1 HETATM 8729 O O . HOH G 7 . ? 63.379 67.844 -31.271 1.00 29.24 ? 5476 HOH A O 1 HETATM 8730 O O . HOH G 7 . ? 65.921 68.147 -30.910 1.00 35.99 ? 5477 HOH A O 1 HETATM 8731 O O . HOH G 7 . ? 61.772 63.747 -30.590 1.00 37.78 ? 5478 HOH A O 1 HETATM 8732 O O . HOH G 7 . ? 67.074 60.045 -27.110 1.00 33.29 ? 5479 HOH A O 1 HETATM 8733 O O . HOH G 7 . ? 68.275 57.552 -26.517 1.00 36.03 ? 5480 HOH A O 1 HETATM 8734 O O . HOH G 7 . ? 68.113 58.719 -23.747 1.00 31.81 ? 5481 HOH A O 1 HETATM 8735 O O . HOH G 7 . ? 70.059 55.236 -22.283 1.00 30.05 ? 5482 HOH A O 1 HETATM 8736 O O . HOH G 7 . ? 66.749 56.361 -19.927 1.00 21.63 ? 5483 HOH A O 1 HETATM 8737 O O . HOH G 7 . ? 67.889 54.925 -17.873 1.00 23.22 ? 5484 HOH A O 1 HETATM 8738 O O . HOH G 7 . ? 70.807 52.053 -12.370 1.00 20.97 ? 5485 HOH A O 1 HETATM 8739 O O . HOH G 7 . ? 73.633 51.467 -11.230 1.00 29.48 ? 5486 HOH A O 1 HETATM 8740 O O . HOH G 7 . ? 70.337 53.740 -9.469 1.00 30.12 ? 5487 HOH A O 1 HETATM 8741 O O . HOH G 7 . ? 72.256 58.618 -10.503 1.00 28.99 ? 5488 HOH A O 1 HETATM 8742 O O . HOH G 7 . ? 74.748 62.876 -7.648 1.00 40.96 ? 5489 HOH A O 1 HETATM 8743 O O . HOH G 7 . ? 73.210 65.048 -7.267 1.00 21.07 ? 5490 HOH A O 1 HETATM 8744 O O . HOH G 7 . ? 73.201 66.704 -9.492 1.00 20.54 ? 5491 HOH A O 1 HETATM 8745 O O . HOH G 7 . ? 75.595 67.048 -9.471 1.00 35.12 ? 5492 HOH A O 1 HETATM 8746 O O . HOH G 7 . ? 78.929 69.080 -11.681 1.00 27.98 ? 5493 HOH A O 1 HETATM 8747 O O . HOH G 7 . ? 81.346 68.342 -11.172 1.00 22.28 ? 5494 HOH A O 1 HETATM 8748 O O . HOH G 7 . ? 81.766 67.095 -13.416 1.00 22.74 ? 5495 HOH A O 1 HETATM 8749 O O . HOH G 7 . ? 79.883 68.100 -14.976 1.00 35.33 ? 5496 HOH A O 1 HETATM 8750 O O . HOH G 7 . ? 84.448 68.231 -17.018 1.00 18.91 ? 5497 HOH A O 1 HETATM 8751 O O . HOH G 7 . ? 83.817 67.561 -22.276 1.00 26.87 ? 5498 HOH A O 1 HETATM 8752 O O . HOH G 7 . ? 80.531 64.176 -20.961 1.00 24.56 ? 5499 HOH A O 1 HETATM 8753 O O . HOH G 7 . ? 78.926 62.480 -22.636 1.00 36.01 ? 5500 HOH A O 1 HETATM 8754 O O . HOH G 7 . ? 73.002 64.332 -20.298 1.00 32.36 ? 5501 HOH A O 1 HETATM 8755 O O . HOH G 7 . ? 72.006 62.607 -17.556 1.00 31.22 ? 5502 HOH A O 1 HETATM 8756 O O . HOH G 7 . ? 70.494 61.810 -20.418 1.00 29.67 ? 5503 HOH A O 1 HETATM 8757 O O . HOH G 7 . ? 70.156 63.215 -23.726 1.00 35.03 ? 5504 HOH A O 1 HETATM 8758 O O . HOH G 7 . ? 72.040 63.441 -25.022 1.00 35.33 ? 5505 HOH A O 1 HETATM 8759 O O . HOH G 7 . ? 69.836 63.780 -28.652 1.00 23.43 ? 5506 HOH A O 1 HETATM 8760 O O . HOH G 7 . ? 71.883 69.601 -34.910 1.00 39.93 ? 5507 HOH A O 1 HETATM 8761 O O . HOH G 7 . ? 70.965 72.885 -33.858 1.00 32.75 ? 5508 HOH A O 1 HETATM 8762 O O . HOH G 7 . ? 68.078 75.131 -34.347 1.00 31.50 ? 5509 HOH A O 1 HETATM 8763 O O . HOH G 7 . ? 69.552 77.206 -33.731 1.00 32.95 ? 5510 HOH A O 1 HETATM 8764 O O . HOH G 7 . ? 68.515 79.684 -34.614 1.00 22.08 ? 5511 HOH A O 1 HETATM 8765 O O . HOH G 7 . ? 64.499 77.918 -34.923 1.00 17.17 ? 5512 HOH A O 1 HETATM 8766 O O . HOH G 7 . ? 63.733 78.701 -37.609 1.00 34.34 ? 5513 HOH A O 1 HETATM 8767 O O . HOH G 7 . ? 64.309 77.181 -40.002 1.00 34.36 ? 5514 HOH A O 1 HETATM 8768 O O . HOH G 7 . ? 61.644 76.773 -39.444 1.00 22.90 ? 5515 HOH A O 1 HETATM 8769 O O . HOH G 7 . ? 60.840 78.904 -41.289 1.00 28.62 ? 5516 HOH A O 1 HETATM 8770 O O . HOH G 7 . ? 58.544 77.331 -38.241 1.00 16.40 ? 5517 HOH A O 1 HETATM 8771 O O . HOH G 7 . ? 61.947 83.422 -37.858 1.00 25.32 ? 5518 HOH A O 1 HETATM 8772 O O . HOH G 7 . ? 67.531 85.534 -36.284 1.00 25.13 ? 5519 HOH A O 1 HETATM 8773 O O . HOH G 7 . ? 68.203 87.989 -35.798 1.00 45.49 ? 5520 HOH A O 1 HETATM 8774 O O . HOH G 7 . ? 69.571 83.909 -35.720 1.00 29.91 ? 5521 HOH A O 1 HETATM 8775 O O . HOH G 7 . ? 72.428 82.860 -30.801 1.00 44.72 ? 5522 HOH A O 1 HETATM 8776 O O . HOH G 7 . ? 70.172 82.975 -29.397 1.00 23.06 ? 5523 HOH A O 1 HETATM 8777 O O . HOH G 7 . ? 71.385 80.225 -27.358 1.00 33.17 ? 5524 HOH A O 1 HETATM 8778 O O . HOH G 7 . ? 70.707 78.183 -25.790 1.00 22.99 ? 5525 HOH A O 1 HETATM 8779 O O . HOH G 7 . ? 72.274 75.900 -26.532 1.00 31.37 ? 5526 HOH A O 1 HETATM 8780 O O . HOH G 7 . ? 71.742 73.937 -28.758 1.00 32.50 ? 5527 HOH A O 1 HETATM 8781 O O . HOH G 7 . ? 77.048 73.980 -25.921 1.00 28.81 ? 5528 HOH A O 1 HETATM 8782 O O . HOH G 7 . ? 75.594 74.293 -18.629 1.00 25.53 ? 5529 HOH A O 1 HETATM 8783 O O . HOH G 7 . ? 74.088 76.730 -19.093 1.00 32.59 ? 5530 HOH A O 1 HETATM 8784 O O . HOH G 7 . ? 72.718 79.793 -16.763 1.00 38.71 ? 5531 HOH A O 1 HETATM 8785 O O . HOH G 7 . ? 68.709 79.128 -17.447 1.00 28.67 ? 5532 HOH A O 1 HETATM 8786 O O . HOH G 7 . ? 66.614 82.087 -13.680 1.00 44.87 ? 5533 HOH A O 1 HETATM 8787 O O . HOH G 7 . ? 65.395 79.506 -8.351 1.00 35.12 ? 5534 HOH A O 1 HETATM 8788 O O . HOH G 7 . ? 61.929 76.403 -10.189 1.00 19.51 ? 5535 HOH A O 1 HETATM 8789 O O . HOH G 7 . ? 61.478 77.236 -12.715 1.00 27.88 ? 5536 HOH A O 1 HETATM 8790 O O . HOH G 7 . ? 59.604 76.486 -8.536 1.00 16.97 ? 5537 HOH A O 1 HETATM 8791 O O . HOH G 7 . ? 57.267 75.294 -2.636 1.00 36.85 ? 5538 HOH A O 1 HETATM 8792 O O . HOH G 7 . ? 57.994 77.206 -1.288 1.00 38.70 ? 5539 HOH A O 1 HETATM 8793 O O . HOH G 7 . ? 56.200 76.033 1.518 1.00 42.58 ? 5540 HOH A O 1 HETATM 8794 O O . HOH G 7 . ? 52.224 73.682 4.361 1.00 41.41 ? 5541 HOH A O 1 HETATM 8795 O O . HOH G 7 . ? 51.106 75.764 5.746 1.00 31.35 ? 5542 HOH A O 1 HETATM 8796 O O . HOH G 7 . ? 49.026 76.619 5.870 1.00 38.79 ? 5543 HOH A O 1 HETATM 8797 O O . HOH G 7 . ? 49.248 77.786 3.342 1.00 38.03 ? 5544 HOH A O 1 HETATM 8798 O O . HOH G 7 . ? 45.737 79.979 5.319 1.00 33.12 ? 5545 HOH A O 1 HETATM 8799 O O . HOH G 7 . ? 43.333 80.629 5.663 1.00 22.44 ? 5546 HOH A O 1 HETATM 8800 O O . HOH G 7 . ? 42.241 83.216 5.230 1.00 32.37 ? 5547 HOH A O 1 HETATM 8801 O O . HOH G 7 . ? 39.109 84.850 1.864 1.00 28.64 ? 5548 HOH A O 1 HETATM 8802 O O . HOH G 7 . ? 41.453 84.752 0.583 1.00 39.30 ? 5549 HOH A O 1 HETATM 8803 O O . HOH G 7 . ? 42.746 83.294 -1.896 1.00 43.43 ? 5550 HOH A O 1 HETATM 8804 O O . HOH G 7 . ? 44.043 82.728 -7.143 1.00 37.09 ? 5551 HOH A O 1 HETATM 8805 O O . HOH G 7 . ? 43.490 82.024 -10.231 1.00 28.49 ? 5552 HOH A O 1 HETATM 8806 O O . HOH G 7 . ? 44.697 84.465 -10.140 1.00 45.53 ? 5553 HOH A O 1 HETATM 8807 O O . HOH G 7 . ? 40.583 82.855 -10.639 1.00 19.41 ? 5554 HOH A O 1 HETATM 8808 O O . HOH G 7 . ? 40.831 85.385 -12.243 1.00 28.56 ? 5555 HOH A O 1 HETATM 8809 O O . HOH G 7 . ? 41.394 77.455 -13.787 1.00 13.87 ? 5556 HOH A O 1 HETATM 8810 O O . HOH G 7 . ? 42.210 75.226 -15.730 1.00 12.23 ? 5557 HOH A O 1 HETATM 8811 O O . HOH G 7 . ? 47.665 79.450 -18.299 1.00 16.90 ? 5558 HOH A O 1 HETATM 8812 O O . HOH G 7 . ? 50.653 78.953 -15.433 1.00 27.70 ? 5559 HOH A O 1 HETATM 8813 O O . HOH G 7 . ? 52.791 78.941 -16.870 1.00 25.02 ? 5560 HOH A O 1 HETATM 8814 O O . HOH G 7 . ? 54.262 80.437 -18.988 1.00 32.41 ? 5561 HOH A O 1 HETATM 8815 O O . HOH G 7 . ? 55.148 81.032 -23.230 1.00 16.60 ? 5562 HOH A O 1 HETATM 8816 O O . HOH G 7 . ? 53.239 87.235 -21.042 1.00 28.51 ? 5563 HOH A O 1 HETATM 8817 O O . HOH G 7 . ? 51.429 90.273 -21.153 1.00 39.28 ? 5564 HOH A O 1 HETATM 8818 O O . HOH G 7 . ? 53.075 91.863 -22.943 1.00 34.52 ? 5565 HOH A O 1 HETATM 8819 O O . HOH G 7 . ? 55.202 90.385 -23.131 1.00 20.19 ? 5566 HOH A O 1 HETATM 8820 O O . HOH G 7 . ? 56.428 91.086 -25.319 1.00 19.82 ? 5567 HOH A O 1 HETATM 8821 O O . HOH G 7 . ? 58.262 93.347 -24.910 1.00 19.86 ? 5568 HOH A O 1 HETATM 8822 O O . HOH G 7 . ? 56.312 92.988 -28.952 1.00 26.18 ? 5569 HOH A O 1 HETATM 8823 O O . HOH G 7 . ? 55.022 93.970 -30.973 1.00 29.23 ? 5570 HOH A O 1 HETATM 8824 O O . HOH G 7 . ? 60.558 91.322 -29.971 1.00 24.52 ? 5571 HOH A O 1 HETATM 8825 O O . HOH G 7 . ? 59.963 91.031 -35.260 1.00 23.07 ? 5572 HOH A O 1 HETATM 8826 O O . HOH G 7 . ? 56.537 89.890 -43.539 1.00 46.46 ? 5573 HOH A O 1 HETATM 8827 O O . HOH G 7 . ? 59.414 87.049 -45.600 1.00 34.57 ? 5574 HOH A O 1 HETATM 8828 O O . HOH G 7 . ? 54.549 82.389 -44.364 1.00 35.10 ? 5575 HOH A O 1 HETATM 8829 O O . HOH G 7 . ? 49.826 82.233 -43.692 1.00 20.35 ? 5576 HOH A O 1 HETATM 8830 O O . HOH G 7 . ? 42.338 87.752 -40.690 1.00 19.80 ? 5577 HOH A O 1 HETATM 8831 O O . HOH G 7 . ? 43.620 88.596 -38.285 1.00 18.76 ? 5578 HOH A O 1 HETATM 8832 O O . HOH G 7 . ? 43.430 93.847 -37.636 1.00 23.65 ? 5579 HOH A O 1 HETATM 8833 O O . HOH G 7 . ? 40.969 96.420 -37.102 1.00 25.78 ? 5580 HOH A O 1 HETATM 8834 O O . HOH G 7 . ? 43.233 98.280 -36.953 1.00 43.58 ? 5581 HOH A O 1 HETATM 8835 O O . HOH G 7 . ? 48.703 98.075 -33.474 1.00 38.68 ? 5582 HOH A O 1 HETATM 8836 O O . HOH G 7 . ? 44.302 95.791 -29.182 1.00 45.49 ? 5583 HOH A O 1 HETATM 8837 O O . HOH G 7 . ? 45.136 90.194 -25.225 1.00 22.02 ? 5584 HOH A O 1 HETATM 8838 O O . HOH G 7 . ? 47.145 89.621 -23.128 1.00 33.91 ? 5585 HOH A O 1 HETATM 8839 O O . HOH G 7 . ? 48.700 91.867 -23.787 1.00 28.62 ? 5586 HOH A O 1 HETATM 8840 O O . HOH G 7 . ? 48.515 89.229 -30.600 1.00 20.47 ? 5587 HOH A O 1 HETATM 8841 O O . HOH G 7 . ? 49.752 84.105 -18.528 1.00 30.95 ? 5588 HOH A O 1 HETATM 8842 O O . HOH G 7 . ? 56.573 87.729 -19.693 1.00 28.59 ? 5589 HOH A O 1 HETATM 8843 O O . HOH G 7 . ? 62.392 85.406 -22.620 1.00 25.99 ? 5590 HOH A O 1 HETATM 8844 O O . HOH G 7 . ? 66.109 84.825 -22.151 1.00 38.22 ? 5591 HOH A O 1 HETATM 8845 O O . HOH G 7 . ? 65.341 87.799 -23.847 1.00 28.37 ? 5592 HOH A O 1 HETATM 8846 O O . HOH G 7 . ? 67.711 88.330 -23.351 1.00 41.87 ? 5593 HOH A O 1 HETATM 8847 O O . HOH G 7 . ? 71.691 84.668 -19.610 1.00 31.96 ? 5594 HOH A O 1 HETATM 8848 O O . HOH G 7 . ? 73.337 82.392 -20.610 1.00 26.22 ? 5595 HOH A O 1 HETATM 8849 O O . HOH G 7 . ? 68.015 81.700 -25.392 1.00 13.48 ? 5596 HOH A O 1 HETATM 8850 O O . HOH G 7 . ? 68.000 78.928 -25.097 1.00 16.56 ? 5597 HOH A O 1 HETATM 8851 O O . HOH G 7 . ? 68.526 79.367 -28.270 1.00 18.05 ? 5598 HOH A O 1 HETATM 8852 O O . HOH G 7 . ? 62.202 80.591 -18.555 1.00 36.41 ? 5599 HOH A O 1 HETATM 8853 O O . HOH G 7 . ? 74.066 80.321 -12.651 1.00 31.37 ? 5600 HOH A O 1 HETATM 8854 O O . HOH G 7 . ? 74.880 77.054 -13.328 1.00 26.00 ? 5601 HOH A O 1 HETATM 8855 O O . HOH G 7 . ? 77.973 76.630 -11.565 1.00 42.48 ? 5602 HOH A O 1 HETATM 8856 O O . HOH G 7 . ? 78.275 71.999 -10.174 1.00 42.19 ? 5603 HOH A O 1 HETATM 8857 O O . HOH G 7 . ? 80.406 71.276 -7.208 1.00 37.66 ? 5604 HOH A O 1 HETATM 8858 O O . HOH G 7 . ? 78.986 69.224 -6.612 1.00 36.44 ? 5605 HOH A O 1 HETATM 8859 O O . HOH G 7 . ? 76.868 68.765 -4.427 1.00 40.47 ? 5606 HOH A O 1 HETATM 8860 O O . HOH G 7 . ? 75.720 70.952 -3.535 1.00 32.16 ? 5607 HOH A O 1 HETATM 8861 O O . HOH G 7 . ? 79.045 69.967 -3.305 1.00 37.33 ? 5608 HOH A O 1 HETATM 8862 O O . HOH G 7 . ? 78.760 71.719 -0.333 1.00 36.27 ? 5609 HOH A O 1 HETATM 8863 O O . HOH G 7 . ? 73.711 74.075 -5.268 1.00 27.17 ? 5610 HOH A O 1 HETATM 8864 O O . HOH G 7 . ? 74.370 76.377 -4.783 1.00 39.28 ? 5611 HOH A O 1 HETATM 8865 O O . HOH G 7 . ? 73.914 80.237 -4.491 1.00 23.87 ? 5612 HOH A O 1 HETATM 8866 O O . HOH G 7 . ? 70.989 80.464 -6.464 1.00 36.99 ? 5613 HOH A O 1 HETATM 8867 O O . HOH G 7 . ? 66.988 74.235 -3.927 1.00 29.52 ? 5614 HOH A O 1 HETATM 8868 O O . HOH G 7 . ? 66.777 71.158 -6.588 1.00 27.63 ? 5615 HOH A O 1 HETATM 8869 O O . HOH G 7 . ? 64.301 70.525 -5.264 1.00 23.02 ? 5616 HOH A O 1 HETATM 8870 O O . HOH G 7 . ? 68.043 65.383 -3.120 1.00 16.18 ? 5617 HOH A O 1 HETATM 8871 O O . HOH G 7 . ? 67.258 65.184 0.095 1.00 42.12 ? 5618 HOH A O 1 HETATM 8872 O O . HOH G 7 . ? 65.642 66.678 0.609 1.00 26.64 ? 5619 HOH A O 1 HETATM 8873 O O . HOH G 7 . ? 66.522 68.223 2.413 1.00 34.75 ? 5620 HOH A O 1 HETATM 8874 O O . HOH G 7 . ? 65.625 66.707 4.416 1.00 39.65 ? 5621 HOH A O 1 HETATM 8875 O O . HOH G 7 . ? 66.147 68.940 4.977 1.00 32.15 ? 5622 HOH A O 1 HETATM 8876 O O . HOH G 7 . ? 59.332 68.283 2.927 1.00 25.76 ? 5623 HOH A O 1 HETATM 8877 O O . HOH G 7 . ? 56.320 66.708 5.868 1.00 28.06 ? 5624 HOH A O 1 HETATM 8878 O O . HOH G 7 . ? 53.971 67.008 7.588 1.00 35.53 ? 5625 HOH A O 1 HETATM 8879 O O . HOH G 7 . ? 51.612 66.270 8.780 1.00 30.66 ? 5626 HOH A O 1 HETATM 8880 O O . HOH G 7 . ? 49.730 67.823 6.719 1.00 37.12 ? 5627 HOH A O 1 HETATM 8881 O O . HOH G 7 . ? 50.012 67.390 4.545 1.00 21.43 ? 5628 HOH A O 1 HETATM 8882 O O . HOH G 7 . ? 52.236 70.852 6.402 1.00 29.46 ? 5629 HOH A O 1 HETATM 8883 O O . HOH G 7 . ? 50.399 72.253 9.603 1.00 22.76 ? 5630 HOH A O 1 HETATM 8884 O O . HOH G 7 . ? 46.706 74.416 8.208 1.00 12.58 ? 5631 HOH A O 1 HETATM 8885 O O . HOH G 7 . ? 46.238 77.387 9.794 1.00 17.06 ? 5632 HOH A O 1 HETATM 8886 O O . HOH G 7 . ? 45.045 80.031 12.660 1.00 31.54 ? 5633 HOH A O 1 HETATM 8887 O O . HOH G 7 . ? 46.957 77.321 13.725 1.00 33.99 ? 5634 HOH A O 1 HETATM 8888 O O . HOH G 7 . ? 50.708 76.214 15.008 1.00 22.42 ? 5635 HOH A O 1 HETATM 8889 O O . HOH G 7 . ? 51.327 77.603 12.562 1.00 40.44 ? 5636 HOH A O 1 HETATM 8890 O O . HOH G 7 . ? 55.261 72.433 16.281 1.00 28.73 ? 5637 HOH A O 1 HETATM 8891 O O . HOH G 7 . ? 52.699 72.245 18.420 1.00 25.98 ? 5638 HOH A O 1 HETATM 8892 O O . HOH G 7 . ? 53.155 69.352 18.235 1.00 33.28 ? 5639 HOH A O 1 HETATM 8893 O O . HOH G 7 . ? 52.003 71.290 21.931 1.00 31.88 ? 5640 HOH A O 1 HETATM 8894 O O . HOH G 7 . ? 48.508 76.525 20.033 1.00 32.50 ? 5641 HOH A O 1 HETATM 8895 O O . HOH G 7 . ? 45.816 74.104 22.726 1.00 33.32 ? 5642 HOH A O 1 HETATM 8896 O O . HOH G 7 . ? 42.459 68.134 26.797 1.00 34.52 ? 5643 HOH A O 1 HETATM 8897 O O . HOH G 7 . ? 33.647 59.914 23.428 1.00 12.34 ? 5644 HOH A O 1 HETATM 8898 O O . HOH G 7 . ? 30.252 55.318 17.385 1.00 9.11 ? 5645 HOH A O 1 HETATM 8899 O O . HOH G 7 . ? 27.702 52.946 20.236 1.00 13.31 ? 5646 HOH A O 1 HETATM 8900 O O . HOH G 7 . ? 26.979 51.710 22.686 1.00 20.08 ? 5647 HOH A O 1 HETATM 8901 O O . HOH G 7 . ? 27.436 49.591 23.482 1.00 20.30 ? 5648 HOH A O 1 HETATM 8902 O O . HOH G 7 . ? 18.188 60.251 24.766 1.00 21.05 ? 5649 HOH A O 1 HETATM 8903 O O . HOH G 7 . ? 12.022 63.142 21.811 1.00 40.83 ? 5650 HOH A O 1 HETATM 8904 O O . HOH G 7 . ? 10.921 68.835 26.135 1.00 29.29 ? 5651 HOH A O 1 HETATM 8905 O O . HOH G 7 . ? 20.571 53.806 47.044 1.00 35.21 ? 5652 HOH A O 1 HETATM 8906 O O . HOH G 7 . ? 20.968 51.208 47.428 1.00 31.81 ? 5653 HOH A O 1 HETATM 8907 O O . HOH G 7 . ? 20.015 42.741 34.072 1.00 25.89 ? 5654 HOH A O 1 HETATM 8908 O O . HOH G 7 . ? 17.365 37.738 35.501 1.00 35.37 ? 5655 HOH A O 1 HETATM 8909 O O . HOH G 7 . ? 15.409 39.138 33.812 1.00 45.40 ? 5656 HOH A O 1 HETATM 8910 O O . HOH G 7 . ? 20.722 31.470 31.548 1.00 31.88 ? 5657 HOH A O 1 HETATM 8911 O O . HOH G 7 . ? 22.516 30.572 29.247 1.00 30.85 ? 5658 HOH A O 1 HETATM 8912 O O . HOH G 7 . ? 21.830 28.708 27.886 1.00 34.54 ? 5659 HOH A O 1 HETATM 8913 O O . HOH G 7 . ? 24.407 34.067 35.753 1.00 29.12 ? 5660 HOH A O 1 HETATM 8914 O O . HOH G 7 . ? 21.026 29.836 17.940 1.00 41.46 ? 5661 HOH A O 1 HETATM 8915 O O . HOH G 7 . ? 16.173 33.662 15.677 1.00 33.63 ? 5662 HOH A O 1 HETATM 8916 O O . HOH G 7 . ? 16.190 36.261 16.538 1.00 31.49 ? 5663 HOH A O 1 HETATM 8917 O O . HOH G 7 . ? 11.737 41.198 19.902 1.00 33.72 ? 5664 HOH A O 1 HETATM 8918 O O . HOH G 7 . ? 8.656 40.087 14.494 1.00 44.65 ? 5665 HOH A O 1 HETATM 8919 O O . HOH G 7 . ? 25.116 29.307 6.993 1.00 43.72 ? 5666 HOH A O 1 HETATM 8920 O O . HOH G 7 . ? 31.162 29.496 5.443 1.00 31.50 ? 5667 HOH A O 1 HETATM 8921 O O . HOH G 7 . ? 31.815 30.616 3.307 1.00 44.77 ? 5668 HOH A O 1 HETATM 8922 O O . HOH G 7 . ? 31.216 33.368 2.648 1.00 24.47 ? 5669 HOH A O 1 HETATM 8923 O O . HOH G 7 . ? 30.216 34.022 -1.235 1.00 25.32 ? 5670 HOH A O 1 HETATM 8924 O O . HOH G 7 . ? 32.300 34.341 -3.213 1.00 22.67 ? 5671 HOH A O 1 HETATM 8925 O O . HOH G 7 . ? 33.332 36.463 -4.381 1.00 14.98 ? 5672 HOH A O 1 HETATM 8926 O O . HOH G 7 . ? 32.484 38.991 -4.880 1.00 9.55 ? 5673 HOH A O 1 HETATM 8927 O O . HOH G 7 . ? 36.037 35.932 -4.517 1.00 18.87 ? 5674 HOH A O 1 HETATM 8928 O O . HOH G 7 . ? 39.019 34.349 -6.880 1.00 36.93 ? 5675 HOH A O 1 HETATM 8929 O O . HOH G 7 . ? 40.052 38.495 -3.326 1.00 25.81 ? 5676 HOH A O 1 HETATM 8930 O O . HOH G 7 . ? 40.042 39.449 -0.060 1.00 25.46 ? 5677 HOH A O 1 HETATM 8931 O O . HOH G 7 . ? 42.020 40.412 0.767 1.00 45.49 ? 5678 HOH A O 1 HETATM 8932 O O . HOH G 7 . ? 42.722 39.298 -1.263 1.00 22.19 ? 5679 HOH A O 1 HETATM 8933 O O . HOH G 7 . ? 44.775 41.658 -0.436 1.00 12.02 ? 5680 HOH A O 1 HETATM 8934 O O . HOH G 7 . ? 46.284 39.869 0.255 1.00 31.55 ? 5681 HOH A O 1 HETATM 8935 O O . HOH G 7 . ? 48.633 40.628 -0.878 1.00 20.10 ? 5682 HOH A O 1 HETATM 8936 O O . HOH G 7 . ? 47.617 42.763 -2.220 1.00 13.50 ? 5683 HOH A O 1 HETATM 8937 O O . HOH G 7 . ? 47.982 41.677 -5.263 1.00 28.88 ? 5684 HOH A O 1 HETATM 8938 O O . HOH G 7 . ? 48.936 44.129 -5.908 1.00 15.89 ? 5685 HOH A O 1 HETATM 8939 O O . HOH G 7 . ? 48.168 43.861 -8.365 1.00 17.77 ? 5686 HOH A O 1 HETATM 8940 O O . HOH G 7 . ? 51.191 44.198 -7.832 1.00 9.97 ? 5687 HOH A O 1 HETATM 8941 O O . HOH G 7 . ? 52.001 40.953 -13.059 1.00 24.65 ? 5688 HOH A O 1 HETATM 8942 O O . HOH G 7 . ? 51.109 40.253 -15.140 1.00 33.75 ? 5689 HOH A O 1 HETATM 8943 O O . HOH G 7 . ? 48.447 38.619 -14.992 1.00 45.49 ? 5690 HOH A O 1 HETATM 8944 O O . HOH G 7 . ? 48.352 36.805 -16.684 1.00 45.49 ? 5691 HOH A O 1 HETATM 8945 O O . HOH G 7 . ? 50.086 40.068 -18.874 1.00 41.95 ? 5692 HOH A O 1 HETATM 8946 O O . HOH G 7 . ? 54.227 40.732 -20.250 1.00 34.75 ? 5693 HOH A O 1 HETATM 8947 O O . HOH G 7 . ? 57.150 39.007 -19.272 1.00 30.42 ? 5694 HOH A O 1 HETATM 8948 O O . HOH G 7 . ? 58.628 37.267 -17.714 1.00 40.25 ? 5695 HOH A O 1 HETATM 8949 O O . HOH G 7 . ? 59.691 37.693 -15.251 1.00 25.15 ? 5696 HOH A O 1 HETATM 8950 O O . HOH G 7 . ? 57.394 35.984 -14.386 1.00 23.89 ? 5697 HOH A O 1 HETATM 8951 O O . HOH G 7 . ? 58.690 34.861 -12.087 1.00 40.72 ? 5698 HOH A O 1 HETATM 8952 O O . HOH G 7 . ? 63.705 34.758 -9.268 1.00 37.15 ? 5699 HOH A O 1 HETATM 8953 O O . HOH G 7 . ? 64.469 39.454 -9.952 1.00 20.04 ? 5700 HOH A O 1 HETATM 8954 O O . HOH G 7 . ? 67.083 38.283 -9.686 1.00 27.08 ? 5701 HOH A O 1 HETATM 8955 O O . HOH G 7 . ? 72.815 42.206 -12.962 1.00 37.93 ? 5702 HOH A O 1 HETATM 8956 O O . HOH G 7 . ? 71.266 43.193 -15.199 1.00 30.44 ? 5703 HOH A O 1 HETATM 8957 O O . HOH G 7 . ? 68.767 46.881 -16.755 1.00 29.49 ? 5704 HOH A O 1 HETATM 8958 O O . HOH G 7 . ? 63.991 50.121 -13.689 1.00 15.66 ? 5705 HOH A O 1 HETATM 8959 O O . HOH G 7 . ? 62.271 48.377 -20.759 1.00 33.69 ? 5706 HOH A O 1 HETATM 8960 O O . HOH G 7 . ? 60.867 46.534 -22.391 1.00 27.31 ? 5707 HOH A O 1 HETATM 8961 O O . HOH G 7 . ? 63.141 42.629 -20.649 1.00 27.74 ? 5708 HOH A O 1 HETATM 8962 O O . HOH G 7 . ? 57.144 43.165 -19.786 1.00 23.23 ? 5709 HOH A O 1 HETATM 8963 O O . HOH G 7 . ? 56.666 46.177 -17.155 1.00 12.88 ? 5710 HOH A O 1 HETATM 8964 O O . HOH G 7 . ? 53.458 47.098 -24.907 1.00 16.29 ? 5711 HOH A O 1 HETATM 8965 O O . HOH G 7 . ? 52.431 45.570 -27.308 1.00 32.31 ? 5712 HOH A O 1 HETATM 8966 O O . HOH G 7 . ? 50.541 44.880 -24.744 1.00 24.39 ? 5713 HOH A O 1 HETATM 8967 O O . HOH G 7 . ? 50.373 47.302 -23.318 1.00 50.58 ? 5714 HOH A O 1 HETATM 8968 O O . HOH G 7 . ? 46.980 42.921 -22.499 1.00 51.77 ? 5715 HOH A O 1 HETATM 8969 O O . HOH G 7 . ? 43.609 43.015 -24.681 1.00 29.63 ? 5716 HOH A O 1 HETATM 8970 O O . HOH G 7 . ? 41.727 44.746 -24.242 1.00 23.57 ? 5717 HOH A O 1 HETATM 8971 O O . HOH G 7 . ? 42.380 47.418 -24.498 1.00 14.66 ? 5718 HOH A O 1 HETATM 8972 O O . HOH G 7 . ? 40.562 45.777 -26.929 1.00 39.22 ? 5719 HOH A O 1 HETATM 8973 O O . HOH G 7 . ? 37.540 45.394 -25.381 1.00 23.75 ? 5720 HOH A O 1 HETATM 8974 O O . HOH G 7 . ? 35.716 45.259 -27.418 1.00 17.94 ? 5721 HOH A O 1 HETATM 8975 O O . HOH G 7 . ? 36.043 42.118 -26.575 1.00 35.99 ? 5722 HOH A O 1 HETATM 8976 O O . HOH G 7 . ? 37.171 41.331 -24.609 1.00 24.13 ? 5723 HOH A O 1 HETATM 8977 O O . HOH G 7 . ? 38.561 39.967 -26.575 1.00 37.53 ? 5724 HOH A O 1 HETATM 8978 O O . HOH G 7 . ? 38.923 42.098 -21.777 1.00 21.45 ? 5725 HOH A O 1 HETATM 8979 O O . HOH G 7 . ? 41.014 40.730 -21.306 1.00 23.41 ? 5726 HOH A O 1 HETATM 8980 O O . HOH G 7 . ? 43.439 40.411 -22.867 1.00 30.45 ? 5727 HOH A O 1 HETATM 8981 O O . HOH G 7 . ? 40.946 37.800 -22.358 1.00 34.83 ? 5728 HOH A O 1 HETATM 8982 O O . HOH G 7 . ? 41.707 41.213 -17.522 1.00 15.16 ? 5729 HOH A O 1 HETATM 8983 O O . HOH G 7 . ? 40.719 41.014 -15.056 1.00 38.70 ? 5730 HOH A O 1 HETATM 8984 O O . HOH G 7 . ? 40.137 42.656 -12.995 1.00 35.56 ? 5731 HOH A O 1 HETATM 8985 O O . HOH G 7 . ? 42.452 40.381 -9.792 1.00 29.37 ? 5732 HOH A O 1 HETATM 8986 O O . HOH G 7 . ? 43.837 41.796 -7.414 1.00 22.80 ? 5733 HOH A O 1 HETATM 8987 O O . HOH G 7 . ? 41.601 44.692 -6.804 1.00 13.77 ? 5734 HOH A O 1 HETATM 8988 O O . HOH G 7 . ? 36.833 44.790 -5.395 1.00 10.19 ? 5735 HOH A O 1 HETATM 8989 O O . HOH G 7 . ? 31.813 46.945 -7.999 1.00 7.69 ? 5736 HOH A O 1 HETATM 8990 O O . HOH G 7 . ? 33.653 48.011 -10.002 1.00 9.78 ? 5737 HOH A O 1 HETATM 8991 O O . HOH G 7 . ? 26.440 48.788 -10.935 1.00 8.62 ? 5738 HOH A O 1 HETATM 8992 O O . HOH G 7 . ? 26.210 49.585 -13.550 1.00 10.13 ? 5739 HOH A O 1 HETATM 8993 O O . HOH G 7 . ? 24.834 52.821 -11.667 1.00 9.52 ? 5740 HOH A O 1 HETATM 8994 O O . HOH G 7 . ? 22.348 54.219 -11.895 1.00 11.37 ? 5741 HOH A O 1 HETATM 8995 O O . HOH G 7 . ? 19.694 53.498 -11.638 1.00 11.04 ? 5742 HOH A O 1 HETATM 8996 O O . HOH G 7 . ? 18.681 50.921 -12.370 1.00 12.44 ? 5743 HOH A O 1 HETATM 8997 O O . HOH G 7 . ? 19.863 46.735 -14.364 1.00 21.89 ? 5744 HOH A O 1 HETATM 8998 O O . HOH G 7 . ? 17.547 45.619 -14.150 1.00 32.50 ? 5745 HOH A O 1 HETATM 8999 O O . HOH G 7 . ? 15.902 44.155 -11.864 1.00 38.69 ? 5746 HOH A O 1 HETATM 9000 O O . HOH G 7 . ? 12.097 46.543 -12.183 1.00 33.13 ? 5747 HOH A O 1 HETATM 9001 O O . HOH G 7 . ? 13.014 51.566 -12.117 1.00 28.04 ? 5748 HOH A O 1 HETATM 9002 O O . HOH G 7 . ? 13.145 51.932 -14.907 1.00 26.44 ? 5749 HOH A O 1 HETATM 9003 O O . HOH G 7 . ? 14.491 54.254 -16.097 1.00 15.68 ? 5750 HOH A O 1 HETATM 9004 O O . HOH G 7 . ? 12.380 55.628 -14.986 1.00 18.72 ? 5751 HOH A O 1 HETATM 9005 O O . HOH G 7 . ? 11.875 54.716 -12.363 1.00 17.23 ? 5752 HOH A O 1 HETATM 9006 O O . HOH G 7 . ? 19.854 57.272 -11.599 1.00 13.62 ? 5753 HOH A O 1 HETATM 9007 O O . HOH G 7 . ? 21.630 57.850 -7.709 1.00 9.54 ? 5754 HOH A O 1 HETATM 9008 O O . HOH G 7 . ? 20.656 57.276 -5.136 1.00 9.36 ? 5755 HOH A O 1 HETATM 9009 O O . HOH G 7 . ? 23.386 53.905 -3.610 1.00 13.71 ? 5756 HOH A O 1 HETATM 9010 O O . HOH G 7 . ? 24.424 55.443 -1.621 1.00 9.63 ? 5757 HOH A O 1 HETATM 9011 O O . HOH G 7 . ? 24.261 53.119 -6.104 1.00 18.41 ? 5758 HOH A O 1 HETATM 9012 O O . HOH G 7 . ? 23.136 51.727 -8.494 1.00 14.48 ? 5759 HOH A O 1 HETATM 9013 O O . HOH G 7 . ? 25.600 51.133 -9.423 1.00 10.63 ? 5760 HOH A O 1 HETATM 9014 O O . HOH G 7 . ? 22.754 45.391 -13.267 1.00 24.40 ? 5761 HOH A O 1 HETATM 9015 O O . HOH G 7 . ? 23.773 45.945 -15.826 1.00 21.34 ? 5762 HOH A O 1 HETATM 9016 O O . HOH G 7 . ? 21.214 46.545 -17.524 1.00 31.39 ? 5763 HOH A O 1 HETATM 9017 O O . HOH G 7 . ? 18.763 48.818 -20.190 1.00 42.77 ? 5764 HOH A O 1 HETATM 9018 O O . HOH G 7 . ? 17.132 50.753 -19.323 1.00 26.81 ? 5765 HOH A O 1 HETATM 9019 O O . HOH G 7 . ? 16.801 52.943 -22.199 1.00 32.58 ? 5766 HOH A O 1 HETATM 9020 O O . HOH G 7 . ? 20.209 52.597 -24.239 1.00 17.81 ? 5767 HOH A O 1 HETATM 9021 O O . HOH G 7 . ? 19.547 50.242 -23.687 1.00 38.79 ? 5768 HOH A O 1 HETATM 9022 O O . HOH G 7 . ? 21.541 48.730 -22.432 1.00 34.23 ? 5769 HOH A O 1 HETATM 9023 O O . HOH G 7 . ? 24.300 48.192 -24.221 1.00 38.69 ? 5770 HOH A O 1 HETATM 9024 O O . HOH G 7 . ? 26.958 47.714 -24.261 1.00 35.51 ? 5771 HOH A O 1 HETATM 9025 O O . HOH G 7 . ? 28.738 49.726 -24.327 1.00 15.89 ? 5772 HOH A O 1 HETATM 9026 O O . HOH G 7 . ? 31.408 50.030 -23.863 1.00 12.05 ? 5773 HOH A O 1 HETATM 9027 O O . HOH G 7 . ? 27.735 48.531 -21.641 1.00 18.45 ? 5774 HOH A O 1 HETATM 9028 O O . HOH G 7 . ? 25.308 46.946 -20.688 1.00 20.98 ? 5775 HOH A O 1 HETATM 9029 O O . HOH G 7 . ? 24.772 51.153 -23.977 1.00 13.50 ? 5776 HOH A O 1 HETATM 9030 O O . HOH G 7 . ? 22.964 53.249 -24.271 1.00 14.27 ? 5777 HOH A O 1 HETATM 9031 O O . HOH G 7 . ? 23.820 55.542 -23.366 1.00 10.98 ? 5778 HOH A O 1 HETATM 9032 O O . HOH G 7 . ? 19.988 52.630 -27.050 1.00 26.25 ? 5779 HOH A O 1 HETATM 9033 O O . HOH G 7 . ? 23.183 48.758 -26.980 1.00 44.86 ? 5780 HOH A O 1 HETATM 9034 O O . HOH G 7 . ? 23.135 48.976 -36.093 1.00 38.17 ? 5781 HOH A O 1 HETATM 9035 O O . HOH G 7 . ? 20.834 55.227 -35.387 1.00 35.69 ? 5782 HOH A O 1 HETATM 9036 O O . HOH G 7 . ? 19.460 54.954 -33.341 1.00 34.77 ? 5783 HOH A O 1 HETATM 9037 O O . HOH G 7 . ? 22.561 56.917 -34.020 1.00 19.26 ? 5784 HOH A O 1 HETATM 9038 O O . HOH G 7 . ? 20.825 59.010 -34.538 1.00 19.90 ? 5785 HOH A O 1 HETATM 9039 O O . HOH G 7 . ? 19.544 58.286 -36.592 1.00 29.04 ? 5786 HOH A O 1 HETATM 9040 O O . HOH G 7 . ? 18.984 60.589 -37.789 1.00 27.06 ? 5787 HOH A O 1 HETATM 9041 O O . HOH G 7 . ? 17.201 57.066 -36.035 1.00 25.28 ? 5788 HOH A O 1 HETATM 9042 O O . HOH G 7 . ? 22.062 61.631 -34.843 1.00 26.57 ? 5789 HOH A O 1 HETATM 9043 O O . HOH G 7 . ? 22.284 63.738 -32.539 1.00 27.68 ? 5790 HOH A O 1 HETATM 9044 O O . HOH G 7 . ? 18.684 70.593 -30.002 1.00 34.18 ? 5791 HOH A O 1 HETATM 9045 O O . HOH G 7 . ? 24.631 71.786 -39.538 1.00 28.51 ? 5792 HOH A O 1 HETATM 9046 O O . HOH G 7 . ? 24.548 74.111 -39.933 1.00 35.27 ? 5793 HOH A O 1 HETATM 9047 O O . HOH G 7 . ? 30.983 69.538 -45.152 1.00 33.07 ? 5794 HOH A O 1 HETATM 9048 O O . HOH G 7 . ? 34.787 65.934 -42.354 1.00 43.93 ? 5795 HOH A O 1 HETATM 9049 O O . HOH G 7 . ? 36.402 62.846 -38.531 1.00 33.95 ? 5796 HOH A O 1 HETATM 9050 O O . HOH G 7 . ? 39.695 58.892 -34.434 1.00 33.76 ? 5797 HOH A O 1 HETATM 9051 O O . HOH G 7 . ? 40.366 62.503 -31.787 1.00 21.10 ? 5798 HOH A O 1 HETATM 9052 O O . HOH G 7 . ? 45.694 61.417 -30.628 1.00 44.25 ? 5799 HOH A O 1 HETATM 9053 O O . HOH G 7 . ? 45.913 56.408 -32.722 1.00 33.46 ? 5800 HOH A O 1 HETATM 9054 O O . HOH G 7 . ? 46.633 54.106 -31.371 1.00 48.55 ? 5801 HOH A O 1 HETATM 9055 O O . HOH G 7 . ? 50.064 55.271 -28.878 1.00 15.25 ? 5802 HOH A O 1 HETATM 9056 O O . HOH G 7 . ? 51.398 53.095 -28.305 1.00 24.54 ? 5803 HOH A O 1 HETATM 9057 O O . HOH G 7 . ? 53.671 53.631 -29.967 1.00 32.31 ? 5804 HOH A O 1 HETATM 9058 O O . HOH G 7 . ? 52.204 56.450 -29.987 1.00 20.40 ? 5805 HOH A O 1 HETATM 9059 O O . HOH G 7 . ? 49.144 50.606 -29.419 1.00 18.67 ? 5806 HOH A O 1 HETATM 9060 O O . HOH G 7 . ? 49.996 49.595 -34.339 1.00 36.03 ? 5807 HOH A O 1 HETATM 9061 O O . HOH G 7 . ? 39.472 48.944 -32.837 1.00 27.77 ? 5808 HOH A O 1 HETATM 9062 O O . HOH G 7 . ? 38.670 45.350 -33.638 1.00 27.87 ? 5809 HOH A O 1 HETATM 9063 O O . HOH G 7 . ? 38.663 51.478 -29.802 1.00 25.26 ? 5810 HOH A O 1 HETATM 9064 O O . HOH G 7 . ? 44.032 54.982 -26.493 1.00 32.76 ? 5811 HOH A O 1 HETATM 9065 O O . HOH G 7 . ? 46.981 55.941 -25.315 1.00 14.99 ? 5812 HOH A O 1 HETATM 9066 O O . HOH G 7 . ? 48.849 55.066 -22.394 1.00 18.25 ? 5813 HOH A O 1 HETATM 9067 O O . HOH G 7 . ? 51.605 53.305 -23.755 1.00 13.40 ? 5814 HOH A O 1 HETATM 9068 O O . HOH G 7 . ? 46.208 52.800 -18.886 1.00 23.52 ? 5815 HOH A O 1 HETATM 9069 O O . HOH G 7 . ? 45.011 55.129 -18.195 1.00 26.61 ? 5816 HOH A O 1 HETATM 9070 O O . HOH G 7 . ? 42.576 54.990 -17.303 1.00 30.46 ? 5817 HOH A O 1 HETATM 9071 O O . HOH G 7 . ? 41.181 52.378 -16.811 1.00 12.85 ? 5818 HOH A O 1 HETATM 9072 O O . HOH G 7 . ? 37.721 51.633 -18.375 1.00 18.43 ? 5819 HOH A O 1 HETATM 9073 O O . HOH G 7 . ? 37.719 52.128 -21.005 1.00 11.09 ? 5820 HOH A O 1 HETATM 9074 O O . HOH G 7 . ? 39.764 53.938 -20.568 1.00 16.59 ? 5821 HOH A O 1 HETATM 9075 O O . HOH G 7 . ? 40.296 56.275 -18.857 1.00 27.59 ? 5822 HOH A O 1 HETATM 9076 O O . HOH G 7 . ? 39.814 58.915 -17.768 1.00 16.46 ? 5823 HOH A O 1 HETATM 9077 O O . HOH G 7 . ? 41.777 58.713 -15.831 1.00 12.84 ? 5824 HOH A O 1 HETATM 9078 O O . HOH G 7 . ? 44.781 58.804 -15.868 1.00 12.44 ? 5825 HOH A O 1 HETATM 9079 O O . HOH G 7 . ? 45.959 59.928 -18.057 1.00 14.79 ? 5826 HOH A O 1 HETATM 9080 O O . HOH G 7 . ? 46.806 57.362 -18.563 1.00 12.78 ? 5827 HOH A O 1 HETATM 9081 O O . HOH G 7 . ? 47.397 55.763 -14.996 1.00 12.97 ? 5828 HOH A O 1 HETATM 9082 O O . HOH G 7 . ? 44.656 56.122 -15.266 1.00 15.58 ? 5829 HOH A O 1 HETATM 9083 O O . HOH G 7 . ? 43.064 59.409 -18.881 1.00 21.59 ? 5830 HOH A O 1 HETATM 9084 O O . HOH G 7 . ? 39.340 62.895 -18.945 1.00 7.79 ? 5831 HOH A O 1 HETATM 9085 O O . HOH G 7 . ? 39.387 64.650 -14.613 1.00 9.97 ? 5832 HOH A O 1 HETATM 9086 O O . HOH G 7 . ? 32.743 64.581 -9.781 1.00 15.71 ? 5833 HOH A O 1 HETATM 9087 O O . HOH G 7 . ? 34.341 58.511 -8.575 1.00 7.29 ? 5834 HOH A O 1 HETATM 9088 O O . HOH G 7 . ? 30.314 58.376 -11.607 1.00 7.80 ? 5835 HOH A O 1 HETATM 9089 O O . HOH G 7 . ? 26.840 60.765 -3.208 1.00 9.15 ? 5836 HOH A O 1 HETATM 9090 O O . HOH G 7 . ? 32.676 59.964 -1.651 1.00 6.76 ? 5837 HOH A O 1 HETATM 9091 O O . HOH G 7 . ? 33.159 62.677 0.377 1.00 7.00 ? 5838 HOH A O 1 HETATM 9092 O O . HOH G 7 . ? 37.630 56.862 1.880 1.00 8.33 ? 5839 HOH A O 1 HETATM 9093 O O . HOH G 7 . ? 39.690 55.489 3.136 1.00 13.21 ? 5840 HOH A O 1 HETATM 9094 O O . HOH G 7 . ? 38.912 52.919 2.085 1.00 24.17 ? 5841 HOH A O 1 HETATM 9095 O O . HOH G 7 . ? 36.054 52.975 1.476 1.00 8.96 ? 5842 HOH A O 1 HETATM 9096 O O . HOH G 7 . ? 34.342 52.251 -0.771 1.00 7.29 ? 5843 HOH A O 1 HETATM 9097 O O . HOH G 7 . ? 36.872 51.444 3.906 1.00 9.71 ? 5844 HOH A O 1 HETATM 9098 O O . HOH G 7 . ? 40.223 56.062 5.939 1.00 10.86 ? 5845 HOH A O 1 HETATM 9099 O O . HOH G 7 . ? 43.061 56.596 6.412 1.00 7.47 ? 5846 HOH A O 1 HETATM 9100 O O . HOH G 7 . ? 42.704 56.148 3.031 1.00 22.71 ? 5847 HOH A O 1 HETATM 9101 O O . HOH G 7 . ? 40.342 62.603 6.374 1.00 10.94 ? 5848 HOH A O 1 HETATM 9102 O O . HOH G 7 . ? 38.862 62.079 8.673 1.00 9.61 ? 5849 HOH A O 1 HETATM 9103 O O . HOH G 7 . ? 37.852 58.763 11.316 1.00 8.87 ? 5850 HOH A O 1 HETATM 9104 O O . HOH G 7 . ? 36.992 57.401 13.519 1.00 9.57 ? 5851 HOH A O 1 HETATM 9105 O O . HOH G 7 . ? 39.362 57.030 14.972 1.00 8.48 ? 5852 HOH A O 1 HETATM 9106 O O . HOH G 7 . ? 41.295 58.740 13.702 1.00 8.91 ? 5853 HOH A O 1 HETATM 9107 O O . HOH G 7 . ? 43.087 47.823 11.335 1.00 11.32 ? 5854 HOH A O 1 HETATM 9108 O O . HOH G 7 . ? 44.421 45.718 10.102 1.00 12.42 ? 5855 HOH A O 1 HETATM 9109 O O . HOH G 7 . ? 46.737 45.902 12.014 1.00 26.79 ? 5856 HOH A O 1 HETATM 9110 O O . HOH G 7 . ? 47.219 48.329 11.718 1.00 17.07 ? 5857 HOH A O 1 HETATM 9111 O O . HOH G 7 . ? 48.028 49.186 14.086 1.00 11.10 ? 5858 HOH A O 1 HETATM 9112 O O . HOH G 7 . ? 48.134 47.956 16.586 1.00 16.60 ? 5859 HOH A O 1 HETATM 9113 O O . HOH G 7 . ? 46.174 45.752 16.339 1.00 36.50 ? 5860 HOH A O 1 HETATM 9114 O O . HOH G 7 . ? 43.742 39.774 18.588 1.00 30.78 ? 5861 HOH A O 1 HETATM 9115 O O . HOH G 7 . ? 41.976 38.746 16.469 1.00 24.77 ? 5862 HOH A O 1 HETATM 9116 O O . HOH G 7 . ? 42.545 36.130 15.944 1.00 29.10 ? 5863 HOH A O 1 HETATM 9117 O O . HOH G 7 . ? 39.299 38.559 17.342 1.00 16.79 ? 5864 HOH A O 1 HETATM 9118 O O . HOH G 7 . ? 35.679 36.148 18.986 1.00 38.99 ? 5865 HOH A O 1 HETATM 9119 O O . HOH G 7 . ? 34.336 34.295 16.363 1.00 18.32 ? 5866 HOH A O 1 HETATM 9120 O O . HOH G 7 . ? 31.962 33.210 16.975 1.00 35.02 ? 5867 HOH A O 1 HETATM 9121 O O . HOH G 7 . ? 32.893 31.013 15.794 1.00 33.57 ? 5868 HOH A O 1 HETATM 9122 O O . HOH G 7 . ? 36.801 28.995 13.134 1.00 31.70 ? 5869 HOH A O 1 HETATM 9123 O O . HOH G 7 . ? 40.183 35.076 11.421 1.00 23.54 ? 5870 HOH A O 1 HETATM 9124 O O . HOH G 7 . ? 40.159 39.031 9.191 1.00 18.69 ? 5871 HOH A O 1 HETATM 9125 O O . HOH G 7 . ? 41.711 43.039 8.179 1.00 13.97 ? 5872 HOH A O 1 HETATM 9126 O O . HOH G 7 . ? 44.435 40.458 8.071 1.00 36.63 ? 5873 HOH A O 1 HETATM 9127 O O . HOH G 7 . ? 46.719 42.473 10.307 1.00 45.88 ? 5874 HOH A O 1 HETATM 9128 O O . HOH G 7 . ? 49.156 41.720 8.448 1.00 29.79 ? 5875 HOH A O 1 HETATM 9129 O O . HOH G 7 . ? 50.123 44.004 7.337 1.00 16.96 ? 5876 HOH A O 1 HETATM 9130 O O . HOH G 7 . ? 49.444 43.964 4.591 1.00 16.12 ? 5877 HOH A O 1 HETATM 9131 O O . HOH G 7 . ? 48.194 41.644 3.922 1.00 19.40 ? 5878 HOH A O 1 HETATM 9132 O O . HOH G 7 . ? 49.887 40.813 1.682 1.00 29.01 ? 5879 HOH A O 1 HETATM 9133 O O . HOH G 7 . ? 51.866 44.264 3.189 1.00 26.00 ? 5880 HOH A O 1 HETATM 9134 O O . HOH G 7 . ? 52.034 46.381 1.516 1.00 10.80 ? 5881 HOH A O 1 HETATM 9135 O O . HOH G 7 . ? 49.987 48.266 1.574 1.00 6.87 ? 5882 HOH A O 1 HETATM 9136 O O . HOH G 7 . ? 47.550 45.826 3.781 1.00 10.59 ? 5883 HOH A O 1 HETATM 9137 O O . HOH G 7 . ? 52.227 50.340 6.496 1.00 11.14 ? 5884 HOH A O 1 HETATM 9138 O O . HOH G 7 . ? 54.241 46.062 8.220 1.00 26.66 ? 5885 HOH A O 1 HETATM 9139 O O . HOH G 7 . ? 52.896 43.392 8.093 1.00 33.21 ? 5886 HOH A O 1 HETATM 9140 O O . HOH G 7 . ? 51.394 44.815 10.078 1.00 33.84 ? 5887 HOH A O 1 HETATM 9141 O O . HOH G 7 . ? 54.385 47.545 15.642 1.00 23.30 ? 5888 HOH A O 1 HETATM 9142 O O . HOH G 7 . ? 55.269 50.139 16.851 1.00 24.18 ? 5889 HOH A O 1 HETATM 9143 O O . HOH G 7 . ? 57.933 48.967 16.873 1.00 28.34 ? 5890 HOH A O 1 HETATM 9144 O O . HOH G 7 . ? 59.059 48.686 19.264 1.00 36.45 ? 5891 HOH A O 1 HETATM 9145 O O . HOH G 7 . ? 57.498 48.605 21.459 1.00 23.49 ? 5892 HOH A O 1 HETATM 9146 O O . HOH G 7 . ? 56.931 46.809 23.361 1.00 32.79 ? 5893 HOH A O 1 HETATM 9147 O O . HOH G 7 . ? 53.897 46.296 23.316 1.00 29.43 ? 5894 HOH A O 1 HETATM 9148 O O . HOH G 7 . ? 53.344 43.876 22.897 1.00 28.91 ? 5895 HOH A O 1 HETATM 9149 O O . HOH G 7 . ? 46.215 44.978 23.681 1.00 30.06 ? 5896 HOH A O 1 HETATM 9150 O O . HOH G 7 . ? 58.670 50.892 22.403 1.00 20.49 ? 5897 HOH A O 1 HETATM 9151 O O . HOH G 7 . ? 60.550 50.779 20.517 1.00 39.11 ? 5898 HOH A O 1 HETATM 9152 O O . HOH G 7 . ? 59.601 50.333 24.972 1.00 30.48 ? 5899 HOH A O 1 HETATM 9153 O O . HOH G 7 . ? 60.041 53.789 15.204 1.00 35.34 ? 5900 HOH A O 1 HETATM 9154 O O . HOH G 7 . ? 61.770 57.597 15.383 1.00 31.19 ? 5901 HOH A O 1 HETATM 9155 O O . HOH G 7 . ? 60.966 59.988 14.476 1.00 44.48 ? 5902 HOH A O 1 HETATM 9156 O O . HOH G 7 . ? 57.781 62.348 8.110 1.00 30.99 ? 5903 HOH A O 1 HETATM 9157 O O . HOH G 7 . ? 58.568 60.625 6.535 1.00 33.14 ? 5904 HOH A O 1 HETATM 9158 O O . HOH G 7 . ? 57.728 58.177 5.850 1.00 26.58 ? 5905 HOH A O 1 HETATM 9159 O O . HOH G 7 . ? 55.358 58.917 4.168 1.00 14.95 ? 5906 HOH A O 1 HETATM 9160 O O . HOH G 7 . ? 56.634 58.461 1.778 1.00 25.90 ? 5907 HOH A O 1 HETATM 9161 O O . HOH G 7 . ? 58.780 57.834 1.297 1.00 29.59 ? 5908 HOH A O 1 HETATM 9162 O O . HOH G 7 . ? 59.812 57.509 3.617 1.00 35.01 ? 5909 HOH A O 1 HETATM 9163 O O . HOH G 7 . ? 61.139 55.962 2.317 1.00 32.46 ? 5910 HOH A O 1 HETATM 9164 O O . HOH G 7 . ? 60.708 54.693 -0.024 1.00 15.41 ? 5911 HOH A O 1 HETATM 9165 O O . HOH G 7 . ? 58.938 52.521 0.203 1.00 13.61 ? 5912 HOH A O 1 HETATM 9166 O O . HOH G 7 . ? 59.471 49.925 -0.263 1.00 15.76 ? 5913 HOH A O 1 HETATM 9167 O O . HOH G 7 . ? 59.659 48.752 2.431 1.00 27.43 ? 5914 HOH A O 1 HETATM 9168 O O . HOH G 7 . ? 59.986 51.653 3.478 1.00 40.40 ? 5915 HOH A O 1 HETATM 9169 O O . HOH G 7 . ? 58.567 52.709 4.855 1.00 25.46 ? 5916 HOH A O 1 HETATM 9170 O O . HOH G 7 . ? 60.185 51.060 6.055 1.00 41.64 ? 5917 HOH A O 1 HETATM 9171 O O . HOH G 7 . ? 59.850 48.929 9.776 1.00 35.73 ? 5918 HOH A O 1 HETATM 9172 O O . HOH G 7 . ? 60.015 44.941 4.974 1.00 32.61 ? 5919 HOH A O 1 HETATM 9173 O O . HOH G 7 . ? 60.471 45.885 1.270 1.00 35.93 ? 5920 HOH A O 1 HETATM 9174 O O . HOH G 7 . ? 59.127 46.271 -1.131 1.00 20.15 ? 5921 HOH A O 1 HETATM 9175 O O . HOH G 7 . ? 63.035 44.373 -0.286 1.00 27.02 ? 5922 HOH A O 1 HETATM 9176 O O . HOH G 7 . ? 66.133 45.418 -2.837 1.00 31.66 ? 5923 HOH A O 1 HETATM 9177 O O . HOH G 7 . ? 67.523 46.497 -1.085 1.00 21.13 ? 5924 HOH A O 1 HETATM 9178 O O . HOH G 7 . ? 68.300 49.203 -0.716 1.00 29.15 ? 5925 HOH A O 1 HETATM 9179 O O . HOH G 7 . ? 71.116 49.407 0.194 1.00 21.42 ? 5926 HOH A O 1 HETATM 9180 O O . HOH G 7 . ? 72.747 50.945 2.162 1.00 29.73 ? 5927 HOH A O 1 HETATM 9181 O O . HOH G 7 . ? 67.651 52.563 1.770 1.00 45.35 ? 5928 HOH A O 1 HETATM 9182 O O . HOH G 7 . ? 67.203 55.427 1.209 1.00 23.03 ? 5929 HOH A O 1 HETATM 9183 O O . HOH G 7 . ? 63.926 56.929 1.090 1.00 27.41 ? 5930 HOH A O 1 HETATM 9184 O O . HOH G 7 . ? 63.373 58.530 -1.176 1.00 18.62 ? 5931 HOH A O 1 HETATM 9185 O O . HOH G 7 . ? 60.942 58.171 -2.535 1.00 13.11 ? 5932 HOH A O 1 HETATM 9186 O O . HOH G 7 . ? 59.029 56.732 -1.119 1.00 13.50 ? 5933 HOH A O 1 HETATM 9187 O O . HOH G 7 . ? 56.502 55.699 -1.783 1.00 9.62 ? 5934 HOH A O 1 HETATM 9188 O O . HOH G 7 . ? 56.288 53.317 -0.472 1.00 7.69 ? 5935 HOH A O 1 HETATM 9189 O O . HOH G 7 . ? 55.078 57.514 -0.115 1.00 14.18 ? 5936 HOH A O 1 HETATM 9190 O O . HOH G 7 . ? 52.984 58.782 -1.569 1.00 15.64 ? 5937 HOH A O 1 HETATM 9191 O O . HOH G 7 . ? 51.624 56.585 -5.372 1.00 7.80 ? 5938 HOH A O 1 HETATM 9192 O O . HOH G 7 . ? 52.324 54.012 -4.696 1.00 8.05 ? 5939 HOH A O 1 HETATM 9193 O O . HOH G 7 . ? 49.900 57.650 -7.284 1.00 9.56 ? 5940 HOH A O 1 HETATM 9194 O O . HOH G 7 . ? 51.015 59.867 -8.672 1.00 12.18 ? 5941 HOH A O 1 HETATM 9195 O O . HOH G 7 . ? 50.144 59.538 -11.215 1.00 9.66 ? 5942 HOH A O 1 HETATM 9196 O O . HOH G 7 . ? 49.715 62.244 -8.416 1.00 10.19 ? 5943 HOH A O 1 HETATM 9197 O O . HOH G 7 . ? 53.793 59.912 -9.037 1.00 10.31 ? 5944 HOH A O 1 HETATM 9198 O O . HOH G 7 . ? 55.752 59.347 -11.247 1.00 8.53 ? 5945 HOH A O 1 HETATM 9199 O O . HOH G 7 . ? 61.158 59.684 -7.961 1.00 9.34 ? 5946 HOH A O 1 HETATM 9200 O O . HOH G 7 . ? 59.666 60.709 -5.882 1.00 16.61 ? 5947 HOH A O 1 HETATM 9201 O O . HOH G 7 . ? 60.852 60.918 -3.270 1.00 16.01 ? 5948 HOH A O 1 HETATM 9202 O O . HOH G 7 . ? 60.682 62.174 -0.974 1.00 15.00 ? 5949 HOH A O 1 HETATM 9203 O O . HOH G 7 . ? 62.519 60.599 0.825 1.00 28.73 ? 5950 HOH A O 1 HETATM 9204 O O . HOH G 7 . ? 60.643 59.935 3.050 1.00 32.70 ? 5951 HOH A O 1 HETATM 9205 O O . HOH G 7 . ? 57.051 60.945 1.862 1.00 15.72 ? 5952 HOH A O 1 HETATM 9206 O O . HOH G 7 . ? 56.493 64.483 9.211 1.00 35.42 ? 5953 HOH A O 1 HETATM 9207 O O . HOH G 7 . ? 57.560 67.392 13.727 1.00 40.84 ? 5954 HOH A O 1 HETATM 9208 O O . HOH G 7 . ? 61.507 73.712 0.434 1.00 32.14 ? 5955 HOH A O 1 HETATM 9209 O O . HOH G 7 . ? 62.126 76.032 0.849 1.00 35.47 ? 5956 HOH A O 1 HETATM 9210 O O . HOH G 7 . ? 65.132 77.199 0.391 1.00 44.45 ? 5957 HOH A O 1 HETATM 9211 O O . HOH G 7 . ? 70.170 69.895 -12.270 1.00 18.97 ? 5958 HOH A O 1 HETATM 9212 O O . HOH G 7 . ? 74.056 65.713 -17.266 1.00 19.04 ? 5959 HOH A O 1 HETATM 9213 O O . HOH G 7 . ? 75.084 64.277 -15.451 1.00 28.27 ? 5960 HOH A O 1 HETATM 9214 O O . HOH G 7 . ? 66.574 62.944 -12.905 1.00 30.70 ? 5961 HOH A O 1 HETATM 9215 O O . HOH G 7 . ? 65.865 60.363 -7.353 1.00 12.77 ? 5962 HOH A O 1 HETATM 9216 O O . HOH G 7 . ? 63.217 61.379 -7.191 1.00 12.52 ? 5963 HOH A O 1 HETATM 9217 O O . HOH G 7 . ? 63.338 61.025 -4.498 1.00 16.05 ? 5964 HOH A O 1 HETATM 9218 O O . HOH G 7 . ? 65.104 59.340 -3.242 1.00 14.49 ? 5965 HOH A O 1 HETATM 9219 O O . HOH G 7 . ? 67.652 60.770 -5.090 1.00 13.24 ? 5966 HOH A O 1 HETATM 9220 O O . HOH G 7 . ? 68.967 58.206 -4.769 1.00 14.85 ? 5967 HOH A O 1 HETATM 9221 O O . HOH G 7 . ? 69.352 61.397 -2.014 1.00 15.45 ? 5968 HOH A O 1 HETATM 9222 O O . HOH G 7 . ? 71.633 59.568 1.236 1.00 30.49 ? 5969 HOH A O 1 HETATM 9223 O O . HOH G 7 . ? 73.404 63.132 0.254 1.00 33.53 ? 5970 HOH A O 1 HETATM 9224 O O . HOH G 7 . ? 79.438 51.291 -0.444 1.00 25.09 ? 5971 HOH A O 1 HETATM 9225 O O . HOH G 7 . ? 76.050 48.349 -4.858 1.00 41.18 ? 5972 HOH A O 1 HETATM 9226 O O . HOH G 7 . ? 75.367 51.376 -6.475 1.00 38.16 ? 5973 HOH A O 1 HETATM 9227 O O . HOH G 7 . ? 78.865 50.175 -8.009 1.00 37.30 ? 5974 HOH A O 1 HETATM 9228 O O . HOH G 7 . ? 79.731 50.423 -10.120 1.00 49.09 ? 5975 HOH A O 1 HETATM 9229 O O . HOH G 7 . ? 77.483 49.410 -10.298 1.00 43.10 ? 5976 HOH A O 1 HETATM 9230 O O . HOH G 7 . ? 63.735 44.728 -6.338 1.00 18.36 ? 5977 HOH A O 1 HETATM 9231 O O . HOH G 7 . ? 63.628 51.776 0.174 1.00 30.75 ? 5978 HOH A O 1 HETATM 9232 O O . HOH G 7 . ? 62.346 51.082 2.300 1.00 42.22 ? 5979 HOH A O 1 HETATM 9233 O O . HOH G 7 . ? 58.188 42.432 1.920 1.00 21.90 ? 5980 HOH A O 1 HETATM 9234 O O . HOH G 7 . ? 55.989 38.570 1.528 1.00 41.29 ? 5981 HOH A O 1 HETATM 9235 O O . HOH G 7 . ? 52.438 36.705 -2.894 1.00 28.69 ? 5982 HOH A O 1 HETATM 9236 O O . HOH G 7 . ? 49.029 38.632 -3.154 1.00 39.11 ? 5983 HOH A O 1 HETATM 9237 O O . HOH G 7 . ? 58.546 34.635 -5.684 1.00 36.64 ? 5984 HOH A O 1 HETATM 9238 O O . HOH G 7 . ? 47.295 41.158 -14.757 1.00 22.21 ? 5985 HOH A O 1 HETATM 9239 O O . HOH G 7 . ? 45.224 39.686 -14.053 1.00 40.72 ? 5986 HOH A O 1 HETATM 9240 O O . HOH G 7 . ? 42.725 39.305 -15.650 1.00 20.97 ? 5987 HOH A O 1 HETATM 9241 O O . HOH G 7 . ? 39.449 38.659 -10.845 1.00 49.41 ? 5988 HOH A O 1 HETATM 9242 O O . HOH G 7 . ? 35.799 38.952 -16.056 1.00 21.95 ? 5989 HOH A O 1 HETATM 9243 O O . HOH G 7 . ? 36.203 36.333 -18.220 1.00 34.66 ? 5990 HOH A O 1 HETATM 9244 O O . HOH G 7 . ? 36.891 34.932 -15.821 1.00 26.44 ? 5991 HOH A O 1 HETATM 9245 O O . HOH G 7 . ? 30.592 35.180 -12.468 1.00 21.12 ? 5992 HOH A O 1 HETATM 9246 O O . HOH G 7 . ? 30.854 34.492 -9.843 1.00 32.39 ? 5993 HOH A O 1 HETATM 9247 O O . HOH G 7 . ? 30.751 33.504 -6.469 1.00 32.72 ? 5994 HOH A O 1 HETATM 9248 O O . HOH G 7 . ? 28.258 35.072 -6.744 1.00 18.48 ? 5995 HOH A O 1 HETATM 9249 O O . HOH G 7 . ? 25.400 34.316 -6.968 1.00 32.68 ? 5996 HOH A O 1 HETATM 9250 O O . HOH G 7 . ? 26.812 41.511 -13.165 1.00 9.92 ? 5997 HOH A O 1 HETATM 9251 O O . HOH G 7 . ? 28.994 42.683 -11.885 1.00 10.56 ? 5998 HOH A O 1 HETATM 9252 O O . HOH G 7 . ? 24.329 42.084 -14.378 1.00 29.16 ? 5999 HOH A O 1 HETATM 9253 O O . HOH G 7 . ? 21.920 42.582 -13.037 1.00 32.24 ? 6000 HOH A O 1 HETATM 9254 O O . HOH G 7 . ? 33.148 40.793 -18.115 1.00 23.70 ? 6001 HOH A O 1 HETATM 9255 O O . HOH G 7 . ? 35.356 50.640 -17.453 1.00 14.68 ? 6002 HOH A O 1 HETATM 9256 O O . HOH G 7 . ? 34.209 56.387 -26.131 1.00 11.40 ? 6003 HOH A O 1 HETATM 9257 O O . HOH G 7 . ? 32.198 58.646 -28.275 1.00 17.70 ? 6004 HOH A O 1 HETATM 9258 O O . HOH G 7 . ? 31.893 51.236 -35.375 1.00 24.20 ? 6005 HOH A O 1 HETATM 9259 O O . HOH G 7 . ? 28.580 59.749 -39.102 1.00 37.81 ? 6006 HOH A O 1 HETATM 9260 O O . HOH G 7 . ? 28.947 62.241 -39.767 1.00 22.54 ? 6007 HOH A O 1 HETATM 9261 O O . HOH G 7 . ? 43.676 68.356 -24.719 1.00 16.73 ? 6008 HOH A O 1 HETATM 9262 O O . HOH G 7 . ? 53.849 64.798 -19.644 1.00 10.55 ? 6009 HOH A O 1 HETATM 9263 O O . HOH G 7 . ? 60.597 60.901 -17.899 1.00 11.99 ? 6010 HOH A O 1 HETATM 9264 O O . HOH G 7 . ? 58.912 53.761 -21.958 1.00 24.07 ? 6011 HOH A O 1 HETATM 9265 O O . HOH G 7 . ? 61.685 54.360 -28.620 1.00 23.12 ? 6012 HOH A O 1 HETATM 9266 O O . HOH G 7 . ? 59.916 52.876 -30.306 1.00 27.43 ? 6013 HOH A O 1 HETATM 9267 O O . HOH G 7 . ? 58.730 44.164 -27.895 1.00 29.36 ? 6014 HOH A O 1 HETATM 9268 O O . HOH G 7 . ? 45.411 34.011 -18.732 1.00 37.59 ? 6015 HOH A O 1 HETATM 9269 O O . HOH G 7 . ? 38.457 39.874 1.802 1.00 9.57 ? 6016 HOH A O 1 HETATM 9270 O O . HOH G 7 . ? 37.814 37.270 3.141 1.00 36.27 ? 6017 HOH A O 1 HETATM 9271 O O . HOH G 7 . ? 39.640 37.153 4.715 1.00 35.40 ? 6018 HOH A O 1 HETATM 9272 O O . HOH G 7 . ? 37.549 33.963 5.363 1.00 40.17 ? 6019 HOH A O 1 HETATM 9273 O O . HOH G 7 . ? 35.211 36.193 3.567 1.00 30.78 ? 6020 HOH A O 1 HETATM 9274 O O . HOH G 7 . ? 30.745 57.027 4.968 1.00 25.91 ? 6021 HOH A O 1 HETATM 9275 O O . HOH G 7 . ? 36.661 72.560 0.624 1.00 9.65 ? 6022 HOH A O 1 HETATM 9276 O O . HOH G 7 . ? 38.011 73.230 -1.990 1.00 12.12 ? 6023 HOH A O 1 HETATM 9277 O O . HOH G 7 . ? 37.174 71.817 -4.208 1.00 9.60 ? 6024 HOH A O 1 HETATM 9278 O O . HOH G 7 . ? 33.464 78.510 -4.611 1.00 12.59 ? 6025 HOH A O 1 HETATM 9279 O O . HOH G 7 . ? 31.456 76.641 -5.999 1.00 11.31 ? 6026 HOH A O 1 HETATM 9280 O O . HOH G 7 . ? 37.511 83.100 -3.572 1.00 23.19 ? 6027 HOH A O 1 HETATM 9281 O O . HOH G 7 . ? 45.849 79.207 -7.461 1.00 24.39 ? 6028 HOH A O 1 HETATM 9282 O O . HOH G 7 . ? 48.390 77.934 -9.618 1.00 27.75 ? 6029 HOH A O 1 HETATM 9283 O O . HOH G 7 . ? 46.160 70.894 0.333 1.00 20.17 ? 6030 HOH A O 1 HETATM 9284 O O . HOH G 7 . ? 43.593 72.869 6.058 1.00 11.34 ? 6031 HOH A O 1 HETATM 9285 O O . HOH G 7 . ? 35.870 80.928 6.924 1.00 22.27 ? 6032 HOH A O 1 HETATM 9286 O O . HOH G 7 . ? 33.304 81.268 7.537 1.00 33.38 ? 6033 HOH A O 1 HETATM 9287 O O . HOH G 7 . ? 35.684 78.444 12.023 1.00 34.68 ? 6034 HOH A O 1 HETATM 9288 O O . HOH G 7 . ? 24.730 70.482 -8.445 1.00 9.01 ? 6035 HOH A O 1 HETATM 9289 O O . HOH G 7 . ? 26.858 68.861 -8.925 1.00 8.80 ? 6036 HOH A O 1 HETATM 9290 O O . HOH G 7 . ? 42.182 63.394 -6.917 1.00 5.86 ? 6037 HOH A O 1 HETATM 9291 O O . HOH G 7 . ? 10.741 58.143 -20.832 1.00 29.86 ? 6038 HOH A O 1 HETATM 9292 O O . HOH G 7 . ? 9.661 60.338 -20.173 1.00 34.54 ? 6039 HOH A O 1 HETATM 9293 O O . HOH G 7 . ? 3.774 55.120 -8.901 1.00 36.86 ? 6040 HOH A O 1 HETATM 9294 O O . HOH G 7 . ? 4.034 56.352 -6.297 1.00 33.92 ? 6041 HOH A O 1 HETATM 9295 O O . HOH G 7 . ? 4.994 52.801 -5.401 1.00 26.33 ? 6042 HOH A O 1 HETATM 9296 O O . HOH G 7 . ? 28.003 101.980 -19.409 1.00 34.26 ? 6043 HOH A O 1 HETATM 9297 O O . HOH G 7 . ? 30.258 102.729 -16.913 1.00 43.07 ? 6044 HOH A O 1 HETATM 9298 O O . HOH G 7 . ? 38.782 98.574 -23.973 1.00 49.11 ? 6045 HOH A O 1 HETATM 9299 O O . HOH G 7 . ? 28.990 93.596 -38.310 1.00 25.57 ? 6046 HOH A O 1 HETATM 9300 O O . HOH G 7 . ? 38.599 94.084 -41.716 1.00 26.17 ? 6047 HOH A O 1 HETATM 9301 O O . HOH G 7 . ? 40.793 87.389 -43.626 1.00 28.48 ? 6048 HOH A O 1 HETATM 9302 O O . HOH G 7 . ? 39.017 86.682 -41.347 1.00 32.78 ? 6049 HOH A O 1 HETATM 9303 O O . HOH G 7 . ? 38.622 83.434 -39.669 1.00 33.43 ? 6050 HOH A O 1 HETATM 9304 O O . HOH G 7 . ? 46.090 96.766 -43.916 1.00 27.98 ? 6051 HOH A O 1 HETATM 9305 O O . HOH G 7 . ? 63.211 74.593 -45.804 1.00 33.16 ? 6052 HOH A O 1 HETATM 9306 O O . HOH G 7 . ? 72.580 95.395 -31.637 1.00 29.35 ? 6053 HOH A O 1 # loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 ARG 1 1 ? ? ? A . n A 1 2 SER 2 2 ? ? ? A . n A 1 3 SER 3 3 ? ? ? A . n A 1 4 HIS 4 4 ? ? ? A . n A 1 5 HIS 5 5 ? ? ? A . n A 1 6 HIS 6 6 ? ? ? A . n A 1 7 HIS 7 7 ? ? ? A . n A 1 8 HIS 8 8 ? ? ? A . n A 1 9 HIS 9 9 ? ? ? A . n A 1 10 GLY 10 10 ? ? ? A . n A 1 11 GLU 11 11 ? ? ? A . n A 1 12 PHE 12 12 ? ? ? A . n A 1 13 ASP 13 13 ? ? ? A . n A 1 14 ASP 14 14 ? ? ? A . n A 1 15 PRO 15 15 ? ? ? A . n A 1 16 ILE 16 16 ? ? ? A . n A 1 17 ARG 17 17 ? ? ? A . n A 1 18 PRO 18 18 ? ? ? A . n A 1 19 PRO 19 19 ? ? ? A . n A 1 20 LEU 20 20 ? ? ? A . n A 1 21 LYS 21 21 ? ? ? A . n A 1 22 VAL 22 22 ? ? ? A . n A 1 23 ALA 23 23 ? ? ? A . n A 1 24 ARG 24 24 ? ? ? A . n A 1 25 SER 25 25 ? ? ? A . n A 1 26 PRO 26 26 ? ? ? A . n A 1 27 ARG 27 27 ? ? ? A . n A 1 28 PRO 28 28 ? ? ? A . n A 1 29 GLY 29 29 ? ? ? A . n A 1 30 GLN 30 30 ? ? ? A . n A 1 31 CYS 31 31 31 CYS CYS A . n A 1 32 GLN 32 32 32 GLN GLN A . n A 1 33 ASP 33 33 33 ASP ASP A . n A 1 34 VAL 34 34 34 VAL VAL A . n A 1 35 VAL 35 35 35 VAL VAL A . n A 1 36 GLN 36 36 36 GLN GLN A . n A 1 37 ASP 37 37 37 ASP ASP A . n A 1 38 VAL 38 38 38 VAL VAL A . n A 1 39 PRO 39 39 39 PRO PRO A . n A 1 40 ASN 40 40 40 ASN ASN A . n A 1 41 VAL 41 41 41 VAL VAL A . n A 1 42 ASP 42 42 42 ASP ASP A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 GLN 44 44 44 GLN GLN A . n A 1 45 MET 45 45 45 MET MET A . n A 1 46 LEU 46 46 46 LEU LEU A . n A 1 47 GLU 47 47 47 GLU GLU A . n A 1 48 LEU 48 48 48 LEU LEU A . n A 1 49 TYR 49 49 49 TYR TYR A . n A 1 50 ASP 50 50 50 ASP ASP A . n A 1 51 ARG 51 51 51 ARG ARG A . n A 1 52 MET 52 52 52 MET MET A . n A 1 53 SER 53 53 53 SER SER A . n A 1 54 PHE 54 54 54 PHE PHE A . n A 1 55 LYS 55 55 55 LYS LYS A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 ILE 57 57 57 ILE ILE A . n A 1 58 ASP 58 58 58 ASP ASP A . n A 1 59 GLY 59 59 59 GLY GLY A . n A 1 60 GLY 60 60 60 GLY GLY A . n A 1 61 VAL 61 61 61 VAL VAL A . n A 1 62 TRP 62 62 62 TRP TRP A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 GLN 64 64 64 GLN GLN A . n A 1 65 GLY 65 65 65 GLY GLY A . n A 1 66 TRP 66 66 66 TRP TRP A . n A 1 67 ASN 67 67 67 ASN ASN A . n A 1 68 ILE 68 68 68 ILE ILE A . n A 1 69 LYS 69 69 69 LYS LYS A . n A 1 70 TYR 70 70 70 TYR TYR A . n A 1 71 ASP 71 71 71 ASP ASP A . n A 1 72 PRO 72 72 72 PRO PRO A . n A 1 73 LEU 73 73 73 LEU LEU A . n A 1 74 LYS 74 74 74 LYS LYS A . n A 1 75 TYR 75 75 75 TYR TYR A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 HIS 78 78 78 HIS HIS A . n A 1 79 HIS 79 79 79 HIS HIS A . n A 1 80 LYS 80 80 80 LYS LYS A . n A 1 81 LEU 81 81 81 LEU LEU A . n A 1 82 LYS 82 82 82 LYS LYS A . n A 1 83 VAL 83 83 83 VAL VAL A . n A 1 84 PHE 84 84 84 PHE PHE A . n A 1 85 VAL 85 85 85 VAL VAL A . n A 1 86 VAL 86 86 86 VAL VAL A . n A 1 87 PRO 87 87 87 PRO PRO A . n A 1 88 HIS 88 88 88 HIS HIS A . n A 1 89 SER 89 89 89 SER SER A . n A 1 90 HIS 90 90 90 HIS HIS A . n A 1 91 ASN 91 91 91 ASN ASN A . n A 1 92 ASP 92 92 92 ASP ASP A . n A 1 93 PRO 93 93 93 PRO PRO A . n A 1 94 GLY 94 94 94 GLY GLY A . n A 1 95 TRP 95 95 95 TRP TRP A . n A 1 96 ILE 96 96 96 ILE ILE A . n A 1 97 GLN 97 97 97 GLN GLN A . n A 1 98 THR 98 98 98 THR THR A . n A 1 99 PHE 99 99 99 PHE PHE A . n A 1 100 GLU 100 100 100 GLU GLU A . n A 1 101 GLU 101 101 101 GLU GLU A . n A 1 102 TYR 102 102 102 TYR TYR A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 GLN 104 104 104 GLN GLN A . n A 1 105 HIS 105 105 105 HIS HIS A . n A 1 106 ASP 106 106 106 ASP ASP A . n A 1 107 THR 107 107 107 THR THR A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 HIS 109 109 109 HIS HIS A . n A 1 110 ILE 110 110 110 ILE ILE A . n A 1 111 LEU 111 111 111 LEU LEU A . n A 1 112 SER 112 112 112 SER SER A . n A 1 113 ASN 113 113 113 ASN ASN A . n A 1 114 ALA 114 114 114 ALA ALA A . n A 1 115 LEU 115 115 115 LEU LEU A . n A 1 116 ARG 116 116 116 ARG ARG A . n A 1 117 HIS 117 117 117 HIS HIS A . n A 1 118 LEU 118 118 118 LEU LEU A . n A 1 119 HIS 119 119 119 HIS HIS A . n A 1 120 ASP 120 120 120 ASP ASP A . n A 1 121 ASN 121 121 121 ASN ASN A . n A 1 122 PRO 122 122 122 PRO PRO A . n A 1 123 GLU 123 123 123 GLU GLU A . n A 1 124 MET 124 124 124 MET MET A . n A 1 125 LYS 125 125 125 LYS LYS A . n A 1 126 PHE 126 126 126 PHE PHE A . n A 1 127 ILE 127 127 127 ILE ILE A . n A 1 128 TRP 128 128 128 TRP TRP A . n A 1 129 ALA 129 129 129 ALA ALA A . n A 1 130 GLU 130 130 130 GLU GLU A . n A 1 131 ILE 131 131 131 ILE ILE A . n A 1 132 SER 132 132 132 SER SER A . n A 1 133 TYR 133 133 133 TYR TYR A . n A 1 134 PHE 134 134 134 PHE PHE A . n A 1 135 ALA 135 135 135 ALA ALA A . n A 1 136 ARG 136 136 136 ARG ARG A . n A 1 137 PHE 137 137 137 PHE PHE A . n A 1 138 TYR 138 138 138 TYR TYR A . n A 1 139 HIS 139 139 139 HIS HIS A . n A 1 140 ASP 140 140 140 ASP ASP A . n A 1 141 LEU 141 141 141 LEU LEU A . n A 1 142 GLY 142 142 142 GLY GLY A . n A 1 143 GLU 143 143 143 GLU GLU A . n A 1 144 ASN 144 144 144 ASN ASN A . n A 1 145 LYS 145 145 145 LYS LYS A . n A 1 146 LYS 146 146 146 LYS LYS A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 GLN 148 148 148 GLN GLN A . n A 1 149 MET 149 149 149 MET MET A . n A 1 150 LYS 150 150 150 LYS LYS A . n A 1 151 SER 151 151 151 SER SER A . n A 1 152 ILE 152 152 152 ILE ILE A . n A 1 153 VAL 153 153 153 VAL VAL A . n A 1 154 LYS 154 154 154 LYS LYS A . n A 1 155 ASN 155 155 155 ASN ASN A . n A 1 156 GLY 156 156 156 GLY GLY A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 LEU 158 158 158 LEU LEU A . n A 1 159 GLU 159 159 159 GLU GLU A . n A 1 160 PHE 160 160 160 PHE PHE A . n A 1 161 VAL 161 161 161 VAL VAL A . n A 1 162 THR 162 162 162 THR THR A . n A 1 163 GLY 163 163 163 GLY GLY A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 TRP 165 165 165 TRP TRP A . n A 1 166 VAL 166 166 166 VAL VAL A . n A 1 167 MET 167 167 167 MET MET A . n A 1 168 PRO 168 168 168 PRO PRO A . n A 1 169 ASP 169 169 169 ASP ASP A . n A 1 170 GLU 170 170 170 GLU GLU A . n A 1 171 ALA 171 171 171 ALA ALA A . n A 1 172 ASN 172 172 172 ASN ASN A . n A 1 173 SER 173 173 173 SER SER A . n A 1 174 HIS 174 174 174 HIS HIS A . n A 1 175 TRP 175 175 175 TRP TRP A . n A 1 176 ARG 176 176 176 ARG ARG A . n A 1 177 ASN 177 177 177 ASN ASN A . n A 1 178 VAL 178 178 178 VAL VAL A . n A 1 179 LEU 179 179 179 LEU LEU A . n A 1 180 LEU 180 180 180 LEU LEU A . n A 1 181 GLN 181 181 181 GLN GLN A . n A 1 182 LEU 182 182 182 LEU LEU A . n A 1 183 THR 183 183 183 THR THR A . n A 1 184 GLU 184 184 184 GLU GLU A . n A 1 185 GLY 185 185 185 GLY GLY A . n A 1 186 GLN 186 186 186 GLN GLN A . n A 1 187 THR 187 187 187 THR THR A . n A 1 188 TRP 188 188 188 TRP TRP A . n A 1 189 LEU 189 189 189 LEU LEU A . n A 1 190 LYS 190 190 190 LYS LYS A . n A 1 191 GLN 191 191 191 GLN GLN A . n A 1 192 PHE 192 192 192 PHE PHE A . n A 1 193 MET 193 193 193 MET MET A . n A 1 194 ASN 194 194 194 ASN ASN A . n A 1 195 VAL 195 195 195 VAL VAL A . n A 1 196 THR 196 196 196 THR THR A . n A 1 197 PRO 197 197 197 PRO PRO A . n A 1 198 THR 198 198 198 THR THR A . n A 1 199 ALA 199 199 199 ALA ALA A . n A 1 200 SER 200 200 200 SER SER A . n A 1 201 TRP 201 201 201 TRP TRP A . n A 1 202 ALA 202 202 202 ALA ALA A . n A 1 203 ILE 203 203 203 ILE ILE A . n A 1 204 ASP 204 204 204 ASP ASP A . n A 1 205 PRO 205 205 205 PRO PRO A . n A 1 206 PHE 206 206 206 PHE PHE A . n A 1 207 GLY 207 207 207 GLY GLY A . n A 1 208 HIS 208 208 208 HIS HIS A . n A 1 209 SER 209 209 209 SER SER A . n A 1 210 PRO 210 210 210 PRO PRO A . n A 1 211 THR 211 211 211 THR THR A . n A 1 212 MET 212 212 212 MET MET A . n A 1 213 PRO 213 213 213 PRO PRO A . n A 1 214 TYR 214 214 214 TYR TYR A . n A 1 215 ILE 215 215 215 ILE ILE A . n A 1 216 LEU 216 216 216 LEU LEU A . n A 1 217 GLN 217 217 217 GLN GLN A . n A 1 218 LYS 218 218 218 LYS LYS A . n A 1 219 SER 219 219 219 SER SER A . n A 1 220 GLY 220 220 220 GLY GLY A . n A 1 221 PHE 221 221 221 PHE PHE A . n A 1 222 LYS 222 222 222 LYS LYS A . n A 1 223 ASN 223 223 223 ASN ASN A . n A 1 224 MET 224 224 224 MET MET A . n A 1 225 LEU 225 225 225 LEU LEU A . n A 1 226 ILE 226 226 226 ILE ILE A . n A 1 227 GLN 227 227 227 GLN GLN A . n A 1 228 ARG 228 228 228 ARG ARG A . n A 1 229 THR 229 229 229 THR THR A . n A 1 230 HIS 230 230 230 HIS HIS A . n A 1 231 TYR 231 231 231 TYR TYR A . n A 1 232 SER 232 232 232 SER SER A . n A 1 233 VAL 233 233 233 VAL VAL A . n A 1 234 LYS 234 234 234 LYS LYS A . n A 1 235 LYS 235 235 235 LYS LYS A . n A 1 236 GLU 236 236 236 GLU GLU A . n A 1 237 LEU 237 237 237 LEU LEU A . n A 1 238 ALA 238 238 238 ALA ALA A . n A 1 239 GLN 239 239 239 GLN GLN A . n A 1 240 GLN 240 240 240 GLN GLN A . n A 1 241 ARG 241 241 241 ARG ARG A . n A 1 242 GLN 242 242 242 GLN GLN A . n A 1 243 LEU 243 243 243 LEU LEU A . n A 1 244 GLU 244 244 244 GLU GLU A . n A 1 245 PHE 245 245 245 PHE PHE A . n A 1 246 LEU 246 246 246 LEU LEU A . n A 1 247 TRP 247 247 247 TRP TRP A . n A 1 248 ARG 248 248 248 ARG ARG A . n A 1 249 GLN 249 249 249 GLN GLN A . n A 1 250 ILE 250 250 250 ILE ILE A . n A 1 251 TRP 251 251 251 TRP TRP A . n A 1 252 ASP 252 252 252 ASP ASP A . n A 1 253 ASN 253 253 253 ASN ASN A . n A 1 254 LYS 254 254 254 LYS LYS A . n A 1 255 GLY 255 255 255 GLY GLY A . n A 1 256 ASP 256 256 256 ASP ASP A . n A 1 257 THR 257 257 257 THR THR A . n A 1 258 ALA 258 258 258 ALA ALA A . n A 1 259 LEU 259 259 259 LEU LEU A . n A 1 260 PHE 260 260 260 PHE PHE A . n A 1 261 THR 261 261 261 THR THR A . n A 1 262 HIS 262 262 262 HIS HIS A . n A 1 263 MET 263 263 263 MET MET A . n A 1 264 MET 264 264 264 MET MET A . n A 1 265 PRO 265 265 265 PRO PRO A . n A 1 266 PHE 266 266 266 PHE PHE A . n A 1 267 TYR 267 267 267 TYR TYR A . n A 1 268 SER 268 268 268 SER SER A . n A 1 269 TYR 269 269 269 TYR TYR A . n A 1 270 ASP 270 270 270 ASP ASP A . n A 1 271 ILE 271 271 271 ILE ILE A . n A 1 272 PRO 272 272 272 PRO PRO A . n A 1 273 HIS 273 273 273 HIS HIS A . n A 1 274 THR 274 274 274 THR THR A . n A 1 275 CYS 275 275 275 CYS CYS A . n A 1 276 GLY 276 276 276 GLY GLY A . n A 1 277 PRO 277 277 277 PRO PRO A . n A 1 278 ASP 278 278 278 ASP ASP A . n A 1 279 PRO 279 279 279 PRO PRO A . n A 1 280 LYS 280 280 280 LYS LYS A . n A 1 281 VAL 281 281 281 VAL VAL A . n A 1 282 CYS 282 282 282 CYS CYS A . n A 1 283 CYS 283 283 283 CYS CYS A . n A 1 284 GLN 284 284 284 GLN GLN A . n A 1 285 PHE 285 285 285 PHE PHE A . n A 1 286 ASP 286 286 286 ASP ASP A . n A 1 287 PHE 287 287 287 PHE PHE A . n A 1 288 LYS 288 288 288 LYS LYS A . n A 1 289 ARG 289 289 289 ARG ARG A . n A 1 290 MET 290 290 290 MET MET A . n A 1 291 GLY 291 291 291 GLY GLY A . n A 1 292 SER 292 292 292 SER SER A . n A 1 293 PHE 293 293 293 PHE PHE A . n A 1 294 GLY 294 294 294 GLY GLY A . n A 1 295 LEU 295 295 295 LEU LEU A . n A 1 296 SER 296 296 296 SER SER A . n A 1 297 CYS 297 297 297 CYS CYS A . n A 1 298 PRO 298 298 298 PRO PRO A . n A 1 299 TRP 299 299 299 TRP TRP A . n A 1 300 LYS 300 300 300 LYS LYS A . n A 1 301 VAL 301 301 301 VAL VAL A . n A 1 302 PRO 302 302 302 PRO PRO A . n A 1 303 PRO 303 303 303 PRO PRO A . n A 1 304 ARG 304 304 304 ARG ARG A . n A 1 305 THR 305 305 305 THR THR A . n A 1 306 ILE 306 306 306 ILE ILE A . n A 1 307 SER 307 307 307 SER SER A . n A 1 308 ASP 308 308 308 ASP ASP A . n A 1 309 GLN 309 309 309 GLN GLN A . n A 1 310 ASN 310 310 310 ASN ASN A . n A 1 311 VAL 311 311 311 VAL VAL A . n A 1 312 ALA 312 312 312 ALA ALA A . n A 1 313 ALA 313 313 313 ALA ALA A . n A 1 314 ARG 314 314 314 ARG ARG A . n A 1 315 SER 315 315 315 SER SER A . n A 1 316 ASP 316 316 316 ASP ASP A . n A 1 317 LEU 317 317 317 LEU LEU A . n A 1 318 LEU 318 318 318 LEU LEU A . n A 1 319 VAL 319 319 319 VAL VAL A . n A 1 320 ASP 320 320 320 ASP ASP A . n A 1 321 GLN 321 321 321 GLN GLN A . n A 1 322 TRP 322 322 322 TRP TRP A . n A 1 323 LYS 323 323 323 LYS LYS A . n A 1 324 LYS 324 324 324 LYS LYS A . n A 1 325 LYS 325 325 325 LYS LYS A . n A 1 326 ALA 326 326 326 ALA ALA A . n A 1 327 GLU 327 327 327 GLU GLU A . n A 1 328 LEU 328 328 328 LEU LEU A . n A 1 329 TYR 329 329 329 TYR TYR A . n A 1 330 ARG 330 330 330 ARG ARG A . n A 1 331 THR 331 331 331 THR THR A . n A 1 332 ASN 332 332 332 ASN ASN A . n A 1 333 VAL 333 333 333 VAL VAL A . n A 1 334 LEU 334 334 334 LEU LEU A . n A 1 335 LEU 335 335 335 LEU LEU A . n A 1 336 ILE 336 336 336 ILE ILE A . n A 1 337 PRO 337 337 337 PRO PRO A . n A 1 338 LEU 338 338 338 LEU LEU A . n A 1 339 GLY 339 339 339 GLY GLY A . n A 1 340 ASP 340 340 340 ASP ASP A . n A 1 341 ASP 341 341 341 ASP ASP A . n A 1 342 PHE 342 342 342 PHE PHE A . n A 1 343 ARG 343 343 343 ARG ARG A . n A 1 344 PHE 344 344 344 PHE PHE A . n A 1 345 LYS 345 345 345 LYS LYS A . n A 1 346 GLN 346 346 346 GLN GLN A . n A 1 347 ASN 347 347 347 ASN ASN A . n A 1 348 THR 348 348 348 THR THR A . n A 1 349 GLU 349 349 349 GLU GLU A . n A 1 350 TRP 350 350 350 TRP TRP A . n A 1 351 ASP 351 351 351 ASP ASP A . n A 1 352 VAL 352 352 352 VAL VAL A . n A 1 353 GLN 353 353 353 GLN GLN A . n A 1 354 ARG 354 354 354 ARG ARG A . n A 1 355 VAL 355 355 355 VAL VAL A . n A 1 356 ASN 356 356 356 ASN ASN A . n A 1 357 TYR 357 357 357 TYR TYR A . n A 1 358 GLU 358 358 358 GLU GLU A . n A 1 359 ARG 359 359 359 ARG ARG A . n A 1 360 LEU 360 360 360 LEU LEU A . n A 1 361 PHE 361 361 361 PHE PHE A . n A 1 362 GLU 362 362 362 GLU GLU A . n A 1 363 HIS 363 363 363 HIS HIS A . n A 1 364 ILE 364 364 364 ILE ILE A . n A 1 365 ASN 365 365 365 ASN ASN A . n A 1 366 SER 366 366 366 SER SER A . n A 1 367 GLN 367 367 367 GLN GLN A . n A 1 368 ALA 368 368 368 ALA ALA A . n A 1 369 HIS 369 369 369 HIS HIS A . n A 1 370 PHE 370 370 370 PHE PHE A . n A 1 371 ASN 371 371 371 ASN ASN A . n A 1 372 VAL 372 372 372 VAL VAL A . n A 1 373 GLN 373 373 373 GLN GLN A . n A 1 374 ALA 374 374 374 ALA ALA A . n A 1 375 GLN 375 375 375 GLN GLN A . n A 1 376 PHE 376 376 376 PHE PHE A . n A 1 377 GLY 377 377 377 GLY GLY A . n A 1 378 THR 378 378 378 THR THR A . n A 1 379 LEU 379 379 379 LEU LEU A . n A 1 380 GLN 380 380 380 GLN GLN A . n A 1 381 GLU 381 381 381 GLU GLU A . n A 1 382 TYR 382 382 382 TYR TYR A . n A 1 383 PHE 383 383 383 PHE PHE A . n A 1 384 ASP 384 384 384 ASP ASP A . n A 1 385 ALA 385 385 385 ALA ALA A . n A 1 386 VAL 386 386 386 VAL VAL A . n A 1 387 HIS 387 387 387 HIS HIS A . n A 1 388 GLN 388 388 388 GLN GLN A . n A 1 389 ALA 389 389 389 ALA ALA A . n A 1 390 GLU 390 390 390 GLU GLU A . n A 1 391 ARG 391 391 391 ARG ARG A . n A 1 392 ALA 392 392 392 ALA ALA A . n A 1 393 GLY 393 393 393 GLY GLY A . n A 1 394 GLN 394 394 394 GLN GLN A . n A 1 395 ALA 395 395 395 ALA ALA A . n A 1 396 GLU 396 396 396 GLU GLU A . n A 1 397 PHE 397 397 397 PHE PHE A . n A 1 398 PRO 398 398 398 PRO PRO A . n A 1 399 THR 399 399 399 THR THR A . n A 1 400 LEU 400 400 400 LEU LEU A . n A 1 401 SER 401 401 401 SER SER A . n A 1 402 GLY 402 402 402 GLY GLY A . n A 1 403 ASP 403 403 403 ASP ASP A . n A 1 404 PHE 404 404 404 PHE PHE A . n A 1 405 PHE 405 405 405 PHE PHE A . n A 1 406 THR 406 406 406 THR THR A . n A 1 407 TYR 407 407 407 TYR TYR A . n A 1 408 ALA 408 408 408 ALA ALA A . n A 1 409 ASP 409 409 409 ASP ASP A . n A 1 410 ARG 410 410 410 ARG ARG A . n A 1 411 SER 411 411 411 SER SER A . n A 1 412 ASP 412 412 412 ASP ASP A . n A 1 413 ASN 413 413 413 ASN ASN A . n A 1 414 TYR 414 414 414 TYR TYR A . n A 1 415 TRP 415 415 415 TRP TRP A . n A 1 416 SER 416 416 416 SER SER A . n A 1 417 GLY 417 417 417 GLY GLY A . n A 1 418 TYR 418 418 418 TYR TYR A . n A 1 419 TYR 419 419 419 TYR TYR A . n A 1 420 THR 420 420 420 THR THR A . n A 1 421 SER 421 421 421 SER SER A . n A 1 422 ARG 422 422 422 ARG ARG A . n A 1 423 PRO 423 423 423 PRO PRO A . n A 1 424 TYR 424 424 424 TYR TYR A . n A 1 425 HIS 425 425 425 HIS HIS A . n A 1 426 LYS 426 426 426 LYS LYS A . n A 1 427 ARG 427 427 427 ARG ARG A . n A 1 428 MET 428 428 428 MET MET A . n A 1 429 ASP 429 429 429 ASP ASP A . n A 1 430 ARG 430 430 430 ARG ARG A . n A 1 431 VAL 431 431 431 VAL VAL A . n A 1 432 LEU 432 432 432 LEU LEU A . n A 1 433 MET 433 433 433 MET MET A . n A 1 434 HIS 434 434 434 HIS HIS A . n A 1 435 TYR 435 435 435 TYR TYR A . n A 1 436 VAL 436 436 436 VAL VAL A . n A 1 437 ARG 437 437 437 ARG ARG A . n A 1 438 ALA 438 438 438 ALA ALA A . n A 1 439 ALA 439 439 439 ALA ALA A . n A 1 440 GLU 440 440 440 GLU GLU A . n A 1 441 MET 441 441 441 MET MET A . n A 1 442 LEU 442 442 442 LEU LEU A . n A 1 443 SER 443 443 443 SER SER A . n A 1 444 ALA 444 444 444 ALA ALA A . n A 1 445 TRP 445 445 445 TRP TRP A . n A 1 446 HIS 446 446 446 HIS HIS A . n A 1 447 SER 447 447 447 SER SER A . n A 1 448 TRP 448 448 448 TRP TRP A . n A 1 449 ASP 449 449 449 ASP ASP A . n A 1 450 GLY 450 450 450 GLY GLY A . n A 1 451 MET 451 451 451 MET MET A . n A 1 452 ALA 452 452 452 ALA ALA A . n A 1 453 ARG 453 453 453 ARG ARG A . n A 1 454 ILE 454 454 454 ILE ILE A . n A 1 455 GLU 455 455 455 GLU GLU A . n A 1 456 GLU 456 456 456 GLU GLU A . n A 1 457 ARG 457 457 457 ARG ARG A . n A 1 458 LEU 458 458 458 LEU LEU A . n A 1 459 GLU 459 459 459 GLU GLU A . n A 1 460 GLN 460 460 460 GLN GLN A . n A 1 461 ALA 461 461 461 ALA ALA A . n A 1 462 ARG 462 462 462 ARG ARG A . n A 1 463 ARG 463 463 463 ARG ARG A . n A 1 464 GLU 464 464 464 GLU GLU A . n A 1 465 LEU 465 465 465 LEU LEU A . n A 1 466 SER 466 466 466 SER SER A . n A 1 467 LEU 467 467 467 LEU LEU A . n A 1 468 PHE 468 468 468 PHE PHE A . n A 1 469 GLN 469 469 469 GLN GLN A . n A 1 470 HIS 470 470 470 HIS HIS A . n A 1 471 HIS 471 471 471 HIS HIS A . n A 1 472 ASP 472 472 472 ASP ASP A . n A 1 473 GLY 473 473 473 GLY GLY A . n A 1 474 ILE 474 474 474 ILE ILE A . n A 1 475 THR 475 475 475 THR THR A . n A 1 476 GLY 476 476 476 GLY GLY A . n A 1 477 THR 477 477 477 THR THR A . n A 1 478 ALA 478 478 478 ALA ALA A . n A 1 479 LYS 479 479 479 LYS LYS A . n A 1 480 THR 480 480 480 THR THR A . n A 1 481 HIS 481 481 481 HIS HIS A . n A 1 482 VAL 482 482 482 VAL VAL A . n A 1 483 VAL 483 483 483 VAL VAL A . n A 1 484 VAL 484 484 484 VAL VAL A . n A 1 485 ASP 485 485 485 ASP ASP A . n A 1 486 TYR 486 486 486 TYR TYR A . n A 1 487 GLU 487 487 487 GLU GLU A . n A 1 488 GLN 488 488 488 GLN GLN A . n A 1 489 ARG 489 489 489 ARG ARG A . n A 1 490 MET 490 490 490 MET MET A . n A 1 491 GLN 491 491 491 GLN GLN A . n A 1 492 GLU 492 492 492 GLU GLU A . n A 1 493 ALA 493 493 493 ALA ALA A . n A 1 494 LEU 494 494 494 LEU LEU A . n A 1 495 LYS 495 495 495 LYS LYS A . n A 1 496 ALA 496 496 496 ALA ALA A . n A 1 497 CYS 497 497 497 CYS CYS A . n A 1 498 GLN 498 498 498 GLN GLN A . n A 1 499 MET 499 499 499 MET MET A . n A 1 500 VAL 500 500 500 VAL VAL A . n A 1 501 MET 501 501 501 MET MET A . n A 1 502 GLN 502 502 502 GLN GLN A . n A 1 503 GLN 503 503 503 GLN GLN A . n A 1 504 SER 504 504 504 SER SER A . n A 1 505 VAL 505 505 505 VAL VAL A . n A 1 506 TYR 506 506 506 TYR TYR A . n A 1 507 ARG 507 507 507 ARG ARG A . n A 1 508 LEU 508 508 508 LEU LEU A . n A 1 509 LEU 509 509 509 LEU LEU A . n A 1 510 THR 510 510 510 THR THR A . n A 1 511 LYS 511 511 511 LYS LYS A . n A 1 512 PRO 512 512 512 PRO PRO A . n A 1 513 SER 513 513 513 SER SER A . n A 1 514 ILE 514 514 514 ILE ILE A . n A 1 515 TYR 515 515 515 TYR TYR A . n A 1 516 SER 516 516 516 SER SER A . n A 1 517 PRO 517 517 517 PRO PRO A . n A 1 518 ASP 518 518 518 ASP ASP A . n A 1 519 PHE 519 519 519 PHE PHE A . n A 1 520 SER 520 520 520 SER SER A . n A 1 521 PHE 521 521 521 PHE PHE A . n A 1 522 SER 522 522 522 SER SER A . n A 1 523 TYR 523 523 523 TYR TYR A . n A 1 524 PHE 524 524 524 PHE PHE A . n A 1 525 THR 525 525 525 THR THR A . n A 1 526 LEU 526 526 526 LEU LEU A . n A 1 527 ASP 527 527 527 ASP ASP A . n A 1 528 ASP 528 528 528 ASP ASP A . n A 1 529 SER 529 529 529 SER SER A . n A 1 530 ARG 530 530 530 ARG ARG A . n A 1 531 TRP 531 531 531 TRP TRP A . n A 1 532 PRO 532 532 532 PRO PRO A . n A 1 533 GLY 533 533 533 GLY GLY A . n A 1 534 SER 534 534 534 SER SER A . n A 1 535 GLY 535 535 535 GLY GLY A . n A 1 536 VAL 536 536 536 VAL VAL A . n A 1 537 GLU 537 537 537 GLU GLU A . n A 1 538 ASP 538 538 538 ASP ASP A . n A 1 539 SER 539 539 539 SER SER A . n A 1 540 ARG 540 540 540 ARG ARG A . n A 1 541 THR 541 541 541 THR THR A . n A 1 542 THR 542 542 542 THR THR A . n A 1 543 ILE 543 543 543 ILE ILE A . n A 1 544 ILE 544 544 544 ILE ILE A . n A 1 545 LEU 545 545 545 LEU LEU A . n A 1 546 GLY 546 546 546 GLY GLY A . n A 1 547 GLU 547 547 547 GLU GLU A . n A 1 548 ASP 548 548 548 ASP ASP A . n A 1 549 ILE 549 549 549 ILE ILE A . n A 1 550 LEU 550 550 550 LEU LEU A . n A 1 551 PRO 551 551 551 PRO PRO A . n A 1 552 SER 552 552 552 SER SER A . n A 1 553 LYS 553 553 553 LYS LYS A . n A 1 554 HIS 554 554 554 HIS HIS A . n A 1 555 VAL 555 555 555 VAL VAL A . n A 1 556 VAL 556 556 556 VAL VAL A . n A 1 557 MET 557 557 557 MET MET A . n A 1 558 HIS 558 558 558 HIS HIS A . n A 1 559 ASN 559 559 559 ASN ASN A . n A 1 560 THR 560 560 560 THR THR A . n A 1 561 LEU 561 561 561 LEU LEU A . n A 1 562 PRO 562 562 562 PRO PRO A . n A 1 563 HIS 563 563 563 HIS HIS A . n A 1 564 TRP 564 564 564 TRP TRP A . n A 1 565 ARG 565 565 565 ARG ARG A . n A 1 566 GLU 566 566 566 GLU GLU A . n A 1 567 GLN 567 567 567 GLN GLN A . n A 1 568 LEU 568 568 568 LEU LEU A . n A 1 569 VAL 569 569 569 VAL VAL A . n A 1 570 ASP 570 570 570 ASP ASP A . n A 1 571 PHE 571 571 571 PHE PHE A . n A 1 572 TYR 572 572 572 TYR TYR A . n A 1 573 VAL 573 573 573 VAL VAL A . n A 1 574 SER 574 574 574 SER SER A . n A 1 575 SER 575 575 575 SER SER A . n A 1 576 PRO 576 576 576 PRO PRO A . n A 1 577 PHE 577 577 577 PHE PHE A . n A 1 578 VAL 578 578 578 VAL VAL A . n A 1 579 SER 579 579 579 SER SER A . n A 1 580 VAL 580 580 580 VAL VAL A . n A 1 581 THR 581 581 581 THR THR A . n A 1 582 ASP 582 582 582 ASP ASP A . n A 1 583 LEU 583 583 583 LEU LEU A . n A 1 584 ALA 584 584 584 ALA ALA A . n A 1 585 ASN 585 585 585 ASN ASN A . n A 1 586 ASN 586 586 586 ASN ASN A . n A 1 587 PRO 587 587 587 PRO PRO A . n A 1 588 VAL 588 588 588 VAL VAL A . n A 1 589 GLU 589 589 589 GLU GLU A . n A 1 590 ALA 590 590 590 ALA ALA A . n A 1 591 GLN 591 591 591 GLN GLN A . n A 1 592 VAL 592 592 592 VAL VAL A . n A 1 593 SER 593 593 593 SER SER A . n A 1 594 PRO 594 594 594 PRO PRO A . n A 1 595 VAL 595 595 595 VAL VAL A . n A 1 596 TRP 596 596 596 TRP TRP A . n A 1 597 SER 597 597 597 SER SER A . n A 1 598 TRP 598 598 598 TRP TRP A . n A 1 599 HIS 599 599 599 HIS HIS A . n A 1 600 HIS 600 600 600 HIS HIS A . n A 1 601 ASP 601 601 601 ASP ASP A . n A 1 602 THR 602 602 602 THR THR A . n A 1 603 LEU 603 603 603 LEU LEU A . n A 1 604 THR 604 604 604 THR THR A . n A 1 605 LYS 605 605 605 LYS LYS A . n A 1 606 THR 606 606 606 THR THR A . n A 1 607 ILE 607 607 607 ILE ILE A . n A 1 608 HIS 608 608 608 HIS HIS A . n A 1 609 PRO 609 609 609 PRO PRO A . n A 1 610 GLN 610 610 610 GLN GLN A . n A 1 611 GLY 611 611 611 GLY GLY A . n A 1 612 SER 612 612 612 SER SER A . n A 1 613 THR 613 613 613 THR THR A . n A 1 614 THR 614 614 614 THR THR A . n A 1 615 LYS 615 615 615 LYS LYS A . n A 1 616 TYR 616 616 616 TYR TYR A . n A 1 617 ARG 617 617 617 ARG ARG A . n A 1 618 ILE 618 618 618 ILE ILE A . n A 1 619 ILE 619 619 619 ILE ILE A . n A 1 620 PHE 620 620 620 PHE PHE A . n A 1 621 LYS 621 621 621 LYS LYS A . n A 1 622 ALA 622 622 622 ALA ALA A . n A 1 623 ARG 623 623 623 ARG ARG A . n A 1 624 VAL 624 624 624 VAL VAL A . n A 1 625 PRO 625 625 625 PRO PRO A . n A 1 626 PRO 626 626 626 PRO PRO A . n A 1 627 MET 627 627 627 MET MET A . n A 1 628 GLY 628 628 628 GLY GLY A . n A 1 629 LEU 629 629 629 LEU LEU A . n A 1 630 ALA 630 630 630 ALA ALA A . n A 1 631 THR 631 631 631 THR THR A . n A 1 632 TYR 632 632 632 TYR TYR A . n A 1 633 VAL 633 633 633 VAL VAL A . n A 1 634 LEU 634 634 634 LEU LEU A . n A 1 635 THR 635 635 635 THR THR A . n A 1 636 ILE 636 636 636 ILE ILE A . n A 1 637 SER 637 637 637 SER SER A . n A 1 638 ASP 638 638 638 ASP ASP A . n A 1 639 SER 639 639 639 SER SER A . n A 1 640 LYS 640 640 640 LYS LYS A . n A 1 641 PRO 641 641 641 PRO PRO A . n A 1 642 GLU 642 642 642 GLU GLU A . n A 1 643 HIS 643 643 643 HIS HIS A . n A 1 644 THR 644 644 644 THR THR A . n A 1 645 SER 645 645 645 SER SER A . n A 1 646 TYR 646 646 646 TYR TYR A . n A 1 647 ALA 647 647 647 ALA ALA A . n A 1 648 SER 648 648 648 SER SER A . n A 1 649 ASN 649 649 649 ASN ASN A . n A 1 650 LEU 650 650 650 LEU LEU A . n A 1 651 LEU 651 651 651 LEU LEU A . n A 1 652 LEU 652 652 652 LEU LEU A . n A 1 653 ARG 653 653 653 ARG ARG A . n A 1 654 LYS 654 654 654 LYS LYS A . n A 1 655 ASN 655 655 655 ASN ASN A . n A 1 656 PRO 656 656 656 PRO PRO A . n A 1 657 THR 657 657 657 THR THR A . n A 1 658 SER 658 658 658 SER SER A . n A 1 659 LEU 659 659 659 LEU LEU A . n A 1 660 PRO 660 660 660 PRO PRO A . n A 1 661 LEU 661 661 661 LEU LEU A . n A 1 662 GLY 662 662 662 GLY GLY A . n A 1 663 GLN 663 663 663 GLN GLN A . n A 1 664 TYR 664 664 664 TYR TYR A . n A 1 665 PRO 665 665 665 PRO PRO A . n A 1 666 GLU 666 666 666 GLU GLU A . n A 1 667 ASP 667 667 667 ASP ASP A . n A 1 668 VAL 668 668 668 VAL VAL A . n A 1 669 LYS 669 669 669 LYS LYS A . n A 1 670 PHE 670 670 670 PHE PHE A . n A 1 671 GLY 671 671 671 GLY GLY A . n A 1 672 ASP 672 672 672 ASP ASP A . n A 1 673 PRO 673 673 673 PRO PRO A . n A 1 674 ARG 674 674 674 ARG ARG A . n A 1 675 GLU 675 675 675 GLU GLU A . n A 1 676 ILE 676 676 676 ILE ILE A . n A 1 677 SER 677 677 677 SER SER A . n A 1 678 LEU 678 678 678 LEU LEU A . n A 1 679 ARG 679 679 679 ARG ARG A . n A 1 680 VAL 680 680 680 VAL VAL A . n A 1 681 GLY 681 681 681 GLY GLY A . n A 1 682 ASN 682 682 682 ASN ASN A . n A 1 683 GLY 683 683 683 GLY GLY A . n A 1 684 PRO 684 684 684 PRO PRO A . n A 1 685 THR 685 685 685 THR THR A . n A 1 686 LEU 686 686 686 LEU LEU A . n A 1 687 ALA 687 687 687 ALA ALA A . n A 1 688 PHE 688 688 688 PHE PHE A . n A 1 689 SER 689 689 689 SER SER A . n A 1 690 GLU 690 690 690 GLU GLU A . n A 1 691 GLN 691 691 691 GLN GLN A . n A 1 692 GLY 692 692 692 GLY GLY A . n A 1 693 LEU 693 693 693 LEU LEU A . n A 1 694 LEU 694 694 694 LEU LEU A . n A 1 695 LYS 695 695 695 LYS LYS A . n A 1 696 SER 696 696 696 SER SER A . n A 1 697 ILE 697 697 697 ILE ILE A . n A 1 698 GLN 698 698 698 GLN GLN A . n A 1 699 LEU 699 699 699 LEU LEU A . n A 1 700 THR 700 700 700 THR THR A . n A 1 701 GLN 701 701 701 GLN GLN A . n A 1 702 ASP 702 702 702 ASP ASP A . n A 1 703 SER 703 703 703 SER SER A . n A 1 704 PRO 704 704 704 PRO PRO A . n A 1 705 HIS 705 705 705 HIS HIS A . n A 1 706 VAL 706 706 706 VAL VAL A . n A 1 707 PRO 707 707 707 PRO PRO A . n A 1 708 VAL 708 708 708 VAL VAL A . n A 1 709 HIS 709 709 709 HIS HIS A . n A 1 710 PHE 710 710 710 PHE PHE A . n A 1 711 LYS 711 711 711 LYS LYS A . n A 1 712 PHE 712 712 712 PHE PHE A . n A 1 713 LEU 713 713 713 LEU LEU A . n A 1 714 LYS 714 714 714 LYS LYS A . n A 1 715 TYR 715 715 715 TYR TYR A . n A 1 716 GLY 716 716 716 GLY GLY A . n A 1 717 VAL 717 717 717 VAL VAL A . n A 1 718 ARG 718 718 718 ARG ARG A . n A 1 719 SER 719 719 719 SER SER A . n A 1 720 HIS 720 720 720 HIS HIS A . n A 1 721 GLY 721 721 721 GLY GLY A . n A 1 722 ASP 722 722 722 ASP ASP A . n A 1 723 ARG 723 723 723 ARG ARG A . n A 1 724 SER 724 724 724 SER SER A . n A 1 725 GLY 725 725 725 GLY GLY A . n A 1 726 ALA 726 726 726 ALA ALA A . n A 1 727 TYR 727 727 727 TYR TYR A . n A 1 728 LEU 728 728 728 LEU LEU A . n A 1 729 PHE 729 729 729 PHE PHE A . n A 1 730 LEU 730 730 730 LEU LEU A . n A 1 731 PRO 731 731 731 PRO PRO A . n A 1 732 ASN 732 732 732 ASN ASN A . n A 1 733 GLY 733 733 733 GLY GLY A . n A 1 734 PRO 734 734 734 PRO PRO A . n A 1 735 ALA 735 735 735 ALA ALA A . n A 1 736 SER 736 736 736 SER SER A . n A 1 737 PRO 737 737 737 PRO PRO A . n A 1 738 VAL 738 738 738 VAL VAL A . n A 1 739 GLU 739 739 739 GLU GLU A . n A 1 740 LEU 740 740 740 LEU LEU A . n A 1 741 GLY 741 741 741 GLY GLY A . n A 1 742 GLN 742 742 742 GLN GLN A . n A 1 743 PRO 743 743 743 PRO PRO A . n A 1 744 VAL 744 744 744 VAL VAL A . n A 1 745 VAL 745 745 745 VAL VAL A . n A 1 746 LEU 746 746 746 LEU LEU A . n A 1 747 VAL 747 747 747 VAL VAL A . n A 1 748 THR 748 748 748 THR THR A . n A 1 749 LYS 749 749 749 LYS LYS A . n A 1 750 GLY 750 750 750 GLY GLY A . n A 1 751 LYS 751 751 751 LYS LYS A . n A 1 752 LEU 752 752 752 LEU LEU A . n A 1 753 GLU 753 753 753 GLU GLU A . n A 1 754 SER 754 754 754 SER SER A . n A 1 755 SER 755 755 755 SER SER A . n A 1 756 VAL 756 756 756 VAL VAL A . n A 1 757 SER 757 757 757 SER SER A . n A 1 758 VAL 758 758 758 VAL VAL A . n A 1 759 GLY 759 759 759 GLY GLY A . n A 1 760 LEU 760 760 760 LEU LEU A . n A 1 761 PRO 761 761 761 PRO PRO A . n A 1 762 SER 762 762 762 SER SER A . n A 1 763 VAL 763 763 763 VAL VAL A . n A 1 764 VAL 764 764 764 VAL VAL A . n A 1 765 HIS 765 765 765 HIS HIS A . n A 1 766 GLN 766 766 766 GLN GLN A . n A 1 767 THR 767 767 767 THR THR A . n A 1 768 ILE 768 768 768 ILE ILE A . n A 1 769 MET 769 769 769 MET MET A . n A 1 770 ARG 770 770 770 ARG ARG A . n A 1 771 GLY 771 771 771 GLY GLY A . n A 1 772 GLY 772 772 772 GLY GLY A . n A 1 773 ALA 773 773 773 ALA ALA A . n A 1 774 PRO 774 774 774 PRO PRO A . n A 1 775 GLU 775 775 775 GLU GLU A . n A 1 776 ILE 776 776 776 ILE ILE A . n A 1 777 ARG 777 777 777 ARG ARG A . n A 1 778 ASN 778 778 778 ASN ASN A . n A 1 779 LEU 779 779 779 LEU LEU A . n A 1 780 VAL 780 780 780 VAL VAL A . n A 1 781 ASP 781 781 781 ASP ASP A . n A 1 782 ILE 782 782 782 ILE ILE A . n A 1 783 GLY 783 783 783 GLY GLY A . n A 1 784 SER 784 784 784 SER SER A . n A 1 785 LEU 785 785 785 LEU LEU A . n A 1 786 ASP 786 786 786 ASP ASP A . n A 1 787 ASN 787 787 787 ASN ASN A . n A 1 788 THR 788 788 788 THR THR A . n A 1 789 GLU 789 789 789 GLU GLU A . n A 1 790 ILE 790 790 790 ILE ILE A . n A 1 791 VAL 791 791 791 VAL VAL A . n A 1 792 MET 792 792 792 MET MET A . n A 1 793 ARG 793 793 793 ARG ARG A . n A 1 794 LEU 794 794 794 LEU LEU A . n A 1 795 GLU 795 795 795 GLU GLU A . n A 1 796 THR 796 796 796 THR THR A . n A 1 797 HIS 797 797 797 HIS HIS A . n A 1 798 ILE 798 798 798 ILE ILE A . n A 1 799 ASP 799 799 799 ASP ASP A . n A 1 800 SER 800 800 800 SER SER A . n A 1 801 GLY 801 801 801 GLY GLY A . n A 1 802 ASP 802 802 802 ASP ASP A . n A 1 803 ILE 803 803 803 ILE ILE A . n A 1 804 PHE 804 804 804 PHE PHE A . n A 1 805 TYR 805 805 805 TYR TYR A . n A 1 806 THR 806 806 806 THR THR A . n A 1 807 ASP 807 807 807 ASP ASP A . n A 1 808 LEU 808 808 808 LEU LEU A . n A 1 809 ASN 809 809 809 ASN ASN A . n A 1 810 GLY 810 810 810 GLY GLY A . n A 1 811 LEU 811 811 811 LEU LEU A . n A 1 812 GLN 812 812 812 GLN GLN A . n A 1 813 PHE 813 813 813 PHE PHE A . n A 1 814 ILE 814 814 814 ILE ILE A . n A 1 815 LYS 815 815 815 LYS LYS A . n A 1 816 ARG 816 816 816 ARG ARG A . n A 1 817 ARG 817 817 817 ARG ARG A . n A 1 818 ARG 818 818 818 ARG ARG A . n A 1 819 LEU 819 819 819 LEU LEU A . n A 1 820 ASP 820 820 820 ASP ASP A . n A 1 821 LYS 821 821 821 LYS LYS A . n A 1 822 LEU 822 822 822 LEU LEU A . n A 1 823 PRO 823 823 823 PRO PRO A . n A 1 824 LEU 824 824 824 LEU LEU A . n A 1 825 GLN 825 825 825 GLN GLN A . n A 1 826 ALA 826 826 826 ALA ALA A . n A 1 827 ASN 827 827 827 ASN ASN A . n A 1 828 TYR 828 828 828 TYR TYR A . n A 1 829 TYR 829 829 829 TYR TYR A . n A 1 830 PRO 830 830 830 PRO PRO A . n A 1 831 ILE 831 831 831 ILE ILE A . n A 1 832 PRO 832 832 832 PRO PRO A . n A 1 833 SER 833 833 833 SER SER A . n A 1 834 GLY 834 834 834 GLY GLY A . n A 1 835 MET 835 835 835 MET MET A . n A 1 836 PHE 836 836 836 PHE PHE A . n A 1 837 ILE 837 837 837 ILE ILE A . n A 1 838 GLU 838 838 838 GLU GLU A . n A 1 839 ASP 839 839 839 ASP ASP A . n A 1 840 ALA 840 840 840 ALA ALA A . n A 1 841 ASN 841 841 841 ASN ASN A . n A 1 842 THR 842 842 842 THR THR A . n A 1 843 ARG 843 843 843 ARG ARG A . n A 1 844 LEU 844 844 844 LEU LEU A . n A 1 845 THR 845 845 845 THR THR A . n A 1 846 LEU 846 846 846 LEU LEU A . n A 1 847 LEU 847 847 847 LEU LEU A . n A 1 848 THR 848 848 848 THR THR A . n A 1 849 GLY 849 849 849 GLY GLY A . n A 1 850 GLN 850 850 850 GLN GLN A . n A 1 851 PRO 851 851 851 PRO PRO A . n A 1 852 LEU 852 852 852 LEU LEU A . n A 1 853 GLY 853 853 853 GLY GLY A . n A 1 854 GLY 854 854 854 GLY GLY A . n A 1 855 SER 855 855 855 SER SER A . n A 1 856 SER 856 856 856 SER SER A . n A 1 857 LEU 857 857 857 LEU LEU A . n A 1 858 ALA 858 858 858 ALA ALA A . n A 1 859 SER 859 859 859 SER SER A . n A 1 860 GLY 860 860 860 GLY GLY A . n A 1 861 GLU 861 861 861 GLU GLU A . n A 1 862 LEU 862 862 862 LEU LEU A . n A 1 863 GLU 863 863 863 GLU GLU A . n A 1 864 ILE 864 864 864 ILE ILE A . n A 1 865 MET 865 865 865 MET MET A . n A 1 866 GLN 866 866 866 GLN GLN A . n A 1 867 ASP 867 867 867 ASP ASP A . n A 1 868 ARG 868 868 868 ARG ARG A . n A 1 869 ARG 869 869 869 ARG ARG A . n A 1 870 LEU 870 870 870 LEU LEU A . n A 1 871 ALA 871 871 871 ALA ALA A . n A 1 872 SER 872 872 872 SER SER A . n A 1 873 ASP 873 873 873 ASP ASP A . n A 1 874 ASP 874 874 874 ASP ASP A . n A 1 875 GLU 875 875 875 GLU GLU A . n A 1 876 ARG 876 876 876 ARG ARG A . n A 1 877 GLY 877 877 877 GLY GLY A . n A 1 878 LEU 878 878 878 LEU LEU A . n A 1 879 GLY 879 879 879 GLY GLY A . n A 1 880 GLN 880 880 880 GLN GLN A . n A 1 881 GLY 881 881 881 GLY GLY A . n A 1 882 VAL 882 882 882 VAL VAL A . n A 1 883 LEU 883 883 883 LEU LEU A . n A 1 884 ASP 884 884 884 ASP ASP A . n A 1 885 ASN 885 885 885 ASN ASN A . n A 1 886 LYS 886 886 886 LYS LYS A . n A 1 887 PRO 887 887 887 PRO PRO A . n A 1 888 VAL 888 888 888 VAL VAL A . n A 1 889 LEU 889 889 889 LEU LEU A . n A 1 890 HIS 890 890 890 HIS HIS A . n A 1 891 ILE 891 891 891 ILE ILE A . n A 1 892 TYR 892 892 892 TYR TYR A . n A 1 893 ARG 893 893 893 ARG ARG A . n A 1 894 LEU 894 894 894 LEU LEU A . n A 1 895 VAL 895 895 895 VAL VAL A . n A 1 896 LEU 896 896 896 LEU LEU A . n A 1 897 GLU 897 897 897 GLU GLU A . n A 1 898 LYS 898 898 898 LYS LYS A . n A 1 899 VAL 899 899 899 VAL VAL A . n A 1 900 ASN 900 900 900 ASN ASN A . n A 1 901 ASN 901 901 901 ASN ASN A . n A 1 902 CYS 902 902 902 CYS CYS A . n A 1 903 VAL 903 903 903 VAL VAL A . n A 1 904 ARG 904 904 904 ARG ARG A . n A 1 905 PRO 905 905 905 PRO PRO A . n A 1 906 SER 906 906 906 SER SER A . n A 1 907 LYS 907 907 907 LYS LYS A . n A 1 908 LEU 908 908 908 LEU LEU A . n A 1 909 HIS 909 909 909 HIS HIS A . n A 1 910 PRO 910 910 910 PRO PRO A . n A 1 911 ALA 911 911 911 ALA ALA A . n A 1 912 GLY 912 912 912 GLY GLY A . n A 1 913 TYR 913 913 913 TYR TYR A . n A 1 914 LEU 914 914 914 LEU LEU A . n A 1 915 THR 915 915 915 THR THR A . n A 1 916 SER 916 916 916 SER SER A . n A 1 917 ALA 917 917 917 ALA ALA A . n A 1 918 ALA 918 918 918 ALA ALA A . n A 1 919 HIS 919 919 919 HIS HIS A . n A 1 920 LYS 920 920 920 LYS LYS A . n A 1 921 ALA 921 921 921 ALA ALA A . n A 1 922 SER 922 922 922 SER SER A . n A 1 923 GLN 923 923 923 GLN GLN A . n A 1 924 SER 924 924 924 SER SER A . n A 1 925 LEU 925 925 925 LEU LEU A . n A 1 926 LEU 926 926 926 LEU LEU A . n A 1 927 ASP 927 927 927 ASP ASP A . n A 1 928 PRO 928 928 928 PRO PRO A . n A 1 929 LEU 929 929 929 LEU LEU A . n A 1 930 ASP 930 930 930 ASP ASP A . n A 1 931 LYS 931 931 931 LYS LYS A . n A 1 932 PHE 932 932 932 PHE PHE A . n A 1 933 ILE 933 933 933 ILE ILE A . n A 1 934 PHE 934 934 934 PHE PHE A . n A 1 935 ALA 935 935 935 ALA ALA A . n A 1 936 GLU 936 936 936 GLU GLU A . n A 1 937 ASN 937 937 937 ASN ASN A . n A 1 938 GLU 938 938 938 GLU GLU A . n A 1 939 TRP 939 939 939 TRP TRP A . n A 1 940 ILE 940 940 940 ILE ILE A . n A 1 941 GLY 941 941 941 GLY GLY A . n A 1 942 ALA 942 942 942 ALA ALA A . n A 1 943 GLN 943 943 943 GLN GLN A . n A 1 944 GLY 944 944 944 GLY GLY A . n A 1 945 GLN 945 945 945 GLN GLN A . n A 1 946 PHE 946 946 946 PHE PHE A . n A 1 947 GLY 947 947 947 GLY GLY A . n A 1 948 GLY 948 948 948 GLY GLY A . n A 1 949 ASP 949 949 949 ASP ASP A . n A 1 950 HIS 950 950 950 HIS HIS A . n A 1 951 PRO 951 951 951 PRO PRO A . n A 1 952 SER 952 952 952 SER SER A . n A 1 953 ALA 953 953 953 ALA ALA A . n A 1 954 ARG 954 954 954 ARG ARG A . n A 1 955 GLU 955 955 955 GLU GLU A . n A 1 956 ASP 956 956 956 ASP ASP A . n A 1 957 LEU 957 957 957 LEU LEU A . n A 1 958 ASP 958 958 958 ASP ASP A . n A 1 959 VAL 959 959 959 VAL VAL A . n A 1 960 SER 960 960 960 SER SER A . n A 1 961 VAL 961 961 961 VAL VAL A . n A 1 962 MET 962 962 962 MET MET A . n A 1 963 ARG 963 963 963 ARG ARG A . n A 1 964 ARG 964 964 964 ARG ARG A . n A 1 965 LEU 965 965 965 LEU LEU A . n A 1 966 THR 966 966 966 THR THR A . n A 1 967 LYS 967 967 967 LYS LYS A . n A 1 968 SER 968 968 968 SER SER A . n A 1 969 SER 969 969 969 SER SER A . n A 1 970 ALA 970 970 970 ALA ALA A . n A 1 971 LYS 971 971 971 LYS LYS A . n A 1 972 THR 972 972 972 THR THR A . n A 1 973 GLN 973 973 973 GLN GLN A . n A 1 974 ARG 974 974 974 ARG ARG A . n A 1 975 VAL 975 975 975 VAL VAL A . n A 1 976 GLY 976 976 976 GLY GLY A . n A 1 977 TYR 977 977 977 TYR TYR A . n A 1 978 VAL 978 978 978 VAL VAL A . n A 1 979 LEU 979 979 979 LEU LEU A . n A 1 980 HIS 980 980 980 HIS HIS A . n A 1 981 ARG 981 981 981 ARG ARG A . n A 1 982 THR 982 982 982 THR THR A . n A 1 983 ASN 983 983 983 ASN ASN A . n A 1 984 LEU 984 984 984 LEU LEU A . n A 1 985 MET 985 985 985 MET MET A . n A 1 986 GLN 986 986 986 GLN GLN A . n A 1 987 CYS 987 987 987 CYS CYS A . n A 1 988 GLY 988 988 988 GLY GLY A . n A 1 989 THR 989 989 989 THR THR A . n A 1 990 PRO 990 990 990 PRO PRO A . n A 1 991 GLU 991 991 991 GLU GLU A . n A 1 992 GLU 992 992 992 GLU GLU A . n A 1 993 HIS 993 993 993 HIS HIS A . n A 1 994 THR 994 994 994 THR THR A . n A 1 995 GLN 995 995 995 GLN GLN A . n A 1 996 LYS 996 996 996 LYS LYS A . n A 1 997 LEU 997 997 997 LEU LEU A . n A 1 998 ASP 998 998 998 ASP ASP A . n A 1 999 VAL 999 999 999 VAL VAL A . n A 1 1000 CYS 1000 1000 1000 CYS CYS A . n A 1 1001 HIS 1001 1001 1001 HIS HIS A . n A 1 1002 LEU 1002 1002 1002 LEU LEU A . n A 1 1003 LEU 1003 1003 1003 LEU LEU A . n A 1 1004 PRO 1004 1004 1004 PRO PRO A . n A 1 1005 ASN 1005 1005 1005 ASN ASN A . n A 1 1006 VAL 1006 1006 1006 VAL VAL A . n A 1 1007 ALA 1007 1007 1007 ALA ALA A . n A 1 1008 ARG 1008 1008 1008 ARG ARG A . n A 1 1009 CYS 1009 1009 1009 CYS CYS A . n A 1 1010 GLU 1010 1010 1010 GLU GLU A . n A 1 1011 ARG 1011 1011 1011 ARG ARG A . n A 1 1012 THR 1012 1012 1012 THR THR A . n A 1 1013 THR 1013 1013 1013 THR THR A . n A 1 1014 LEU 1014 1014 1014 LEU LEU A . n A 1 1015 THR 1015 1015 1015 THR THR A . n A 1 1016 PHE 1016 1016 1016 PHE PHE A . n A 1 1017 LEU 1017 1017 1017 LEU LEU A . n A 1 1018 GLN 1018 1018 1018 GLN GLN A . n A 1 1019 ASN 1019 1019 1019 ASN ASN A . n A 1 1020 LEU 1020 1020 1020 LEU LEU A . n A 1 1021 GLU 1021 1021 1021 GLU GLU A . n A 1 1022 HIS 1022 1022 1022 HIS HIS A . n A 1 1023 LEU 1023 1023 1023 LEU LEU A . n A 1 1024 ASP 1024 1024 1024 ASP ASP A . n A 1 1025 GLY 1025 1025 1025 GLY GLY A . n A 1 1026 MET 1026 1026 1026 MET MET A . n A 1 1027 VAL 1027 1027 1027 VAL VAL A . n A 1 1028 ALA 1028 1028 1028 ALA ALA A . n A 1 1029 PRO 1029 1029 1029 PRO PRO A . n A 1 1030 GLU 1030 1030 1030 GLU GLU A . n A 1 1031 VAL 1031 1031 1031 VAL VAL A . n A 1 1032 CYS 1032 1032 1032 CYS CYS A . n A 1 1033 PRO 1033 1033 1033 PRO PRO A . n A 1 1034 MET 1034 1034 1034 MET MET A . n A 1 1035 GLU 1035 1035 1035 GLU GLU A . n A 1 1036 THR 1036 1036 1036 THR THR A . n A 1 1037 ALA 1037 1037 1037 ALA ALA A . n A 1 1038 ALA 1038 1038 1038 ALA ALA A . n A 1 1039 TYR 1039 1039 1039 TYR TYR A . n A 1 1040 VAL 1040 1040 1040 VAL VAL A . n A 1 1041 SER 1041 1041 1041 SER SER A . n A 1 1042 SER 1042 1042 1042 SER SER A . n A 1 1043 HIS 1043 1043 1043 HIS HIS A . n A 1 1044 SER 1044 1044 1044 SER SER A . n A 1 1045 SER 1045 1045 ? ? ? A . n # loop_ _pdbx_nonpoly_scheme.asym_id _pdbx_nonpoly_scheme.entity_id _pdbx_nonpoly_scheme.mon_id _pdbx_nonpoly_scheme.ndb_seq_num _pdbx_nonpoly_scheme.pdb_seq_num _pdbx_nonpoly_scheme.auth_seq_num _pdbx_nonpoly_scheme.pdb_mon_id _pdbx_nonpoly_scheme.auth_mon_id _pdbx_nonpoly_scheme.pdb_strand_id _pdbx_nonpoly_scheme.pdb_ins_code B 2 NAG 1 5004 5004 NAG NAG A . C 3 ZN 1 5001 5001 ZN ZN A . D 4 PO4 1 5005 5005 PO4 PO4 A . E 5 MSN 1 5002 5002 MSN MSN A . F 6 MPD 1 5003 5003 MPD MPD A . G 7 HOH 1 5006 1 HOH HOH A . G 7 HOH 2 5007 2 HOH HOH A . G 7 HOH 3 5008 3 HOH HOH A . G 7 HOH 4 5009 4 HOH HOH A . G 7 HOH 5 5010 5 HOH HOH A . G 7 HOH 6 5011 6 HOH HOH A . G 7 HOH 7 5012 7 HOH HOH A . G 7 HOH 8 5013 8 HOH HOH A . G 7 HOH 9 5014 9 HOH HOH A . G 7 HOH 10 5015 10 HOH HOH A . G 7 HOH 11 5016 11 HOH HOH A . G 7 HOH 12 5017 12 HOH HOH A . G 7 HOH 13 5018 13 HOH HOH A . G 7 HOH 14 5019 14 HOH HOH A . G 7 HOH 15 5020 15 HOH HOH A . G 7 HOH 16 5021 16 HOH HOH A . G 7 HOH 17 5022 17 HOH HOH A . G 7 HOH 18 5023 18 HOH HOH A . G 7 HOH 19 5024 19 HOH HOH A . G 7 HOH 20 5025 20 HOH HOH A . G 7 HOH 21 5026 21 HOH HOH A . G 7 HOH 22 5027 22 HOH HOH A . G 7 HOH 23 5028 23 HOH HOH A . G 7 HOH 24 5029 24 HOH HOH A . G 7 HOH 25 5030 25 HOH HOH A . G 7 HOH 26 5031 26 HOH HOH A . G 7 HOH 27 5032 27 HOH HOH A . G 7 HOH 28 5033 28 HOH HOH A . G 7 HOH 29 5034 29 HOH HOH A . G 7 HOH 30 5035 30 HOH HOH A . G 7 HOH 31 5036 31 HOH HOH A . G 7 HOH 32 5037 32 HOH HOH A . G 7 HOH 33 5038 33 HOH HOH A . G 7 HOH 34 5039 34 HOH HOH A . G 7 HOH 35 5040 35 HOH HOH A . G 7 HOH 36 5041 36 HOH HOH A . G 7 HOH 37 5042 37 HOH HOH A . G 7 HOH 38 5043 38 HOH HOH A . G 7 HOH 39 5044 39 HOH HOH A . G 7 HOH 40 5045 40 HOH HOH A . G 7 HOH 41 5046 41 HOH HOH A . G 7 HOH 42 5047 42 HOH HOH A . G 7 HOH 43 5048 43 HOH HOH A . G 7 HOH 44 5049 44 HOH HOH A . G 7 HOH 45 5050 45 HOH HOH A . G 7 HOH 46 5051 46 HOH HOH A . G 7 HOH 47 5052 47 HOH HOH A . G 7 HOH 48 5053 48 HOH HOH A . G 7 HOH 49 5054 49 HOH HOH A . G 7 HOH 50 5055 50 HOH HOH A . G 7 HOH 51 5056 51 HOH HOH A . G 7 HOH 52 5057 52 HOH HOH A . G 7 HOH 53 5058 53 HOH HOH A . G 7 HOH 54 5059 54 HOH HOH A . G 7 HOH 55 5060 55 HOH HOH A . G 7 HOH 56 5061 56 HOH HOH A . G 7 HOH 57 5062 57 HOH HOH A . G 7 HOH 58 5063 58 HOH HOH A . G 7 HOH 59 5064 59 HOH HOH A . G 7 HOH 60 5065 60 HOH HOH A . G 7 HOH 61 5066 61 HOH HOH A . G 7 HOH 62 5067 62 HOH HOH A . G 7 HOH 63 5068 63 HOH HOH A . G 7 HOH 64 5069 64 HOH HOH A . G 7 HOH 65 5070 65 HOH HOH A . G 7 HOH 66 5071 66 HOH HOH A . G 7 HOH 67 5072 67 HOH HOH A . G 7 HOH 68 5073 68 HOH HOH A . G 7 HOH 69 5074 69 HOH HOH A . G 7 HOH 70 5075 70 HOH HOH A . G 7 HOH 71 5076 71 HOH HOH A . G 7 HOH 72 5077 72 HOH HOH A . G 7 HOH 73 5078 73 HOH HOH A . G 7 HOH 74 5079 74 HOH HOH A . G 7 HOH 75 5080 75 HOH HOH A . G 7 HOH 76 5081 76 HOH HOH A . G 7 HOH 77 5082 77 HOH HOH A . G 7 HOH 78 5083 78 HOH HOH A . G 7 HOH 79 5084 79 HOH HOH A . G 7 HOH 80 5085 80 HOH HOH A . G 7 HOH 81 5086 81 HOH HOH A . G 7 HOH 82 5087 82 HOH HOH A . G 7 HOH 83 5088 83 HOH HOH A . G 7 HOH 84 5089 84 HOH HOH A . G 7 HOH 85 5090 85 HOH HOH A . G 7 HOH 86 5091 86 HOH HOH A . G 7 HOH 87 5092 87 HOH HOH A . G 7 HOH 88 5093 88 HOH HOH A . G 7 HOH 89 5094 89 HOH HOH A . G 7 HOH 90 5095 90 HOH HOH A . G 7 HOH 91 5096 91 HOH HOH A . G 7 HOH 92 5097 92 HOH HOH A . G 7 HOH 93 5098 93 HOH HOH A . G 7 HOH 94 5099 94 HOH HOH A . G 7 HOH 95 5100 95 HOH HOH A . G 7 HOH 96 5101 96 HOH HOH A . G 7 HOH 97 5102 97 HOH HOH A . G 7 HOH 98 5103 98 HOH HOH A . G 7 HOH 99 5104 99 HOH HOH A . G 7 HOH 100 5105 100 HOH HOH A . G 7 HOH 101 5106 101 HOH HOH A . G 7 HOH 102 5107 102 HOH HOH A . G 7 HOH 103 5108 103 HOH HOH A . G 7 HOH 104 5109 104 HOH HOH A . G 7 HOH 105 5110 105 HOH HOH A . G 7 HOH 106 5111 106 HOH HOH A . G 7 HOH 107 5112 107 HOH HOH A . G 7 HOH 108 5113 108 HOH HOH A . G 7 HOH 109 5114 109 HOH HOH A . G 7 HOH 110 5115 110 HOH HOH A . G 7 HOH 111 5116 111 HOH HOH A . G 7 HOH 112 5117 112 HOH HOH A . G 7 HOH 113 5118 113 HOH HOH A . G 7 HOH 114 5119 114 HOH HOH A . G 7 HOH 115 5120 115 HOH HOH A . G 7 HOH 116 5121 116 HOH HOH A . G 7 HOH 117 5122 117 HOH HOH A . G 7 HOH 118 5123 118 HOH HOH A . G 7 HOH 119 5124 119 HOH HOH A . G 7 HOH 120 5125 120 HOH HOH A . G 7 HOH 121 5126 121 HOH HOH A . G 7 HOH 122 5127 122 HOH HOH A . G 7 HOH 123 5128 123 HOH HOH A . G 7 HOH 124 5129 124 HOH HOH A . G 7 HOH 125 5130 125 HOH HOH A . G 7 HOH 126 5131 126 HOH HOH A . G 7 HOH 127 5132 127 HOH HOH A . G 7 HOH 128 5133 128 HOH HOH A . G 7 HOH 129 5134 129 HOH HOH A . G 7 HOH 130 5135 130 HOH HOH A . G 7 HOH 131 5136 131 HOH HOH A . G 7 HOH 132 5137 132 HOH HOH A . G 7 HOH 133 5138 133 HOH HOH A . G 7 HOH 134 5139 134 HOH HOH A . G 7 HOH 135 5140 135 HOH HOH A . G 7 HOH 136 5141 136 HOH HOH A . G 7 HOH 137 5142 137 HOH HOH A . G 7 HOH 138 5143 138 HOH HOH A . G 7 HOH 139 5144 139 HOH HOH A . G 7 HOH 140 5145 140 HOH HOH A . G 7 HOH 141 5146 141 HOH HOH A . G 7 HOH 142 5147 142 HOH HOH A . G 7 HOH 143 5148 143 HOH HOH A . G 7 HOH 144 5149 144 HOH HOH A . G 7 HOH 145 5150 145 HOH HOH A . G 7 HOH 146 5151 146 HOH HOH A . G 7 HOH 147 5152 147 HOH HOH A . G 7 HOH 148 5153 148 HOH HOH A . G 7 HOH 149 5154 149 HOH HOH A . G 7 HOH 150 5155 150 HOH HOH A . G 7 HOH 151 5156 151 HOH HOH A . G 7 HOH 152 5157 152 HOH HOH A . G 7 HOH 153 5158 153 HOH HOH A . G 7 HOH 154 5159 154 HOH HOH A . G 7 HOH 155 5160 155 HOH HOH A . G 7 HOH 156 5161 156 HOH HOH A . G 7 HOH 157 5162 157 HOH HOH A . G 7 HOH 158 5163 158 HOH HOH A . G 7 HOH 159 5164 159 HOH HOH A . G 7 HOH 160 5165 160 HOH HOH A . G 7 HOH 161 5166 161 HOH HOH A . G 7 HOH 162 5167 162 HOH HOH A . G 7 HOH 163 5168 163 HOH HOH A . G 7 HOH 164 5169 164 HOH HOH A . G 7 HOH 165 5170 165 HOH HOH A . G 7 HOH 166 5171 166 HOH HOH A . G 7 HOH 167 5172 167 HOH HOH A . G 7 HOH 168 5173 168 HOH HOH A . G 7 HOH 169 5174 169 HOH HOH A . G 7 HOH 170 5175 170 HOH HOH A . G 7 HOH 171 5176 171 HOH HOH A . G 7 HOH 172 5177 172 HOH HOH A . G 7 HOH 173 5178 173 HOH HOH A . G 7 HOH 174 5179 174 HOH HOH A . G 7 HOH 175 5180 175 HOH HOH A . G 7 HOH 176 5181 176 HOH HOH A . G 7 HOH 177 5182 177 HOH HOH A . G 7 HOH 178 5183 178 HOH HOH A . G 7 HOH 179 5184 179 HOH HOH A . G 7 HOH 180 5185 180 HOH HOH A . G 7 HOH 181 5186 181 HOH HOH A . G 7 HOH 182 5187 182 HOH HOH A . G 7 HOH 183 5188 183 HOH HOH A . G 7 HOH 184 5189 184 HOH HOH A . G 7 HOH 185 5190 185 HOH HOH A . G 7 HOH 186 5191 186 HOH HOH A . G 7 HOH 187 5192 187 HOH HOH A . G 7 HOH 188 5193 188 HOH HOH A . G 7 HOH 189 5194 189 HOH HOH A . G 7 HOH 190 5195 190 HOH HOH A . G 7 HOH 191 5196 191 HOH HOH A . G 7 HOH 192 5197 192 HOH HOH A . G 7 HOH 193 5198 193 HOH HOH A . G 7 HOH 194 5199 194 HOH HOH A . G 7 HOH 195 5200 195 HOH HOH A . G 7 HOH 196 5201 196 HOH HOH A . G 7 HOH 197 5202 197 HOH HOH A . G 7 HOH 198 5203 198 HOH HOH A . G 7 HOH 199 5204 199 HOH HOH A . G 7 HOH 200 5205 200 HOH HOH A . G 7 HOH 201 5206 201 HOH HOH A . G 7 HOH 202 5207 202 HOH HOH A . G 7 HOH 203 5208 203 HOH HOH A . G 7 HOH 204 5209 204 HOH HOH A . G 7 HOH 205 5210 205 HOH HOH A . G 7 HOH 206 5211 206 HOH HOH A . G 7 HOH 207 5212 207 HOH HOH A . G 7 HOH 208 5213 208 HOH HOH A . G 7 HOH 209 5214 209 HOH HOH A . G 7 HOH 210 5215 210 HOH HOH A . G 7 HOH 211 5216 211 HOH HOH A . G 7 HOH 212 5217 212 HOH HOH A . G 7 HOH 213 5218 213 HOH HOH A . G 7 HOH 214 5219 214 HOH HOH A . G 7 HOH 215 5220 215 HOH HOH A . G 7 HOH 216 5221 216 HOH HOH A . G 7 HOH 217 5222 217 HOH HOH A . G 7 HOH 218 5223 218 HOH HOH A . G 7 HOH 219 5224 219 HOH HOH A . G 7 HOH 220 5225 220 HOH HOH A . G 7 HOH 221 5226 221 HOH HOH A . G 7 HOH 222 5227 222 HOH HOH A . G 7 HOH 223 5228 223 HOH HOH A . G 7 HOH 224 5229 224 HOH HOH A . G 7 HOH 225 5230 225 HOH HOH A . G 7 HOH 226 5231 226 HOH HOH A . G 7 HOH 227 5232 227 HOH HOH A . G 7 HOH 228 5233 228 HOH HOH A . G 7 HOH 229 5234 229 HOH HOH A . G 7 HOH 230 5235 230 HOH HOH A . G 7 HOH 231 5236 231 HOH HOH A . G 7 HOH 232 5237 232 HOH HOH A . G 7 HOH 233 5238 233 HOH HOH A . G 7 HOH 234 5239 234 HOH HOH A . G 7 HOH 235 5240 235 HOH HOH A . G 7 HOH 236 5241 236 HOH HOH A . G 7 HOH 237 5242 237 HOH HOH A . G 7 HOH 238 5243 238 HOH HOH A . G 7 HOH 239 5244 239 HOH HOH A . G 7 HOH 240 5245 240 HOH HOH A . G 7 HOH 241 5246 241 HOH HOH A . G 7 HOH 242 5247 242 HOH HOH A . G 7 HOH 243 5248 243 HOH HOH A . G 7 HOH 244 5249 244 HOH HOH A . G 7 HOH 245 5250 245 HOH HOH A . G 7 HOH 246 5251 246 HOH HOH A . G 7 HOH 247 5252 247 HOH HOH A . G 7 HOH 248 5253 248 HOH HOH A . G 7 HOH 249 5254 249 HOH HOH A . G 7 HOH 250 5255 250 HOH HOH A . G 7 HOH 251 5256 251 HOH HOH A . G 7 HOH 252 5257 252 HOH HOH A . G 7 HOH 253 5258 253 HOH HOH A . G 7 HOH 254 5259 254 HOH HOH A . G 7 HOH 255 5260 255 HOH HOH A . G 7 HOH 256 5261 256 HOH HOH A . G 7 HOH 257 5262 257 HOH HOH A . G 7 HOH 258 5263 258 HOH HOH A . G 7 HOH 259 5264 259 HOH HOH A . G 7 HOH 260 5265 260 HOH HOH A . G 7 HOH 261 5266 261 HOH HOH A . G 7 HOH 262 5267 262 HOH HOH A . G 7 HOH 263 5268 263 HOH HOH A . G 7 HOH 264 5269 264 HOH HOH A . G 7 HOH 265 5270 265 HOH HOH A . G 7 HOH 266 5271 266 HOH HOH A . G 7 HOH 267 5272 267 HOH HOH A . G 7 HOH 268 5273 268 HOH HOH A . G 7 HOH 269 5274 269 HOH HOH A . G 7 HOH 270 5275 270 HOH HOH A . G 7 HOH 271 5276 271 HOH HOH A . G 7 HOH 272 5277 272 HOH HOH A . G 7 HOH 273 5278 273 HOH HOH A . G 7 HOH 274 5279 274 HOH HOH A . G 7 HOH 275 5280 275 HOH HOH A . G 7 HOH 276 5281 276 HOH HOH A . G 7 HOH 277 5282 277 HOH HOH A . G 7 HOH 278 5283 278 HOH HOH A . G 7 HOH 279 5284 279 HOH HOH A . G 7 HOH 280 5285 280 HOH HOH A . G 7 HOH 281 5286 281 HOH HOH A . G 7 HOH 282 5287 282 HOH HOH A . G 7 HOH 283 5288 283 HOH HOH A . G 7 HOH 284 5289 284 HOH HOH A . G 7 HOH 285 5290 285 HOH HOH A . G 7 HOH 286 5291 286 HOH HOH A . G 7 HOH 287 5292 287 HOH HOH A . G 7 HOH 288 5293 288 HOH HOH A . G 7 HOH 289 5294 289 HOH HOH A . G 7 HOH 290 5295 290 HOH HOH A . G 7 HOH 291 5296 291 HOH HOH A . G 7 HOH 292 5297 292 HOH HOH A . G 7 HOH 293 5298 293 HOH HOH A . G 7 HOH 294 5299 294 HOH HOH A . G 7 HOH 295 5300 295 HOH HOH A . G 7 HOH 296 5301 296 HOH HOH A . G 7 HOH 297 5302 297 HOH HOH A . G 7 HOH 298 5303 298 HOH HOH A . G 7 HOH 299 5304 299 HOH HOH A . G 7 HOH 300 5305 300 HOH HOH A . G 7 HOH 301 5306 301 HOH HOH A . G 7 HOH 302 5307 302 HOH HOH A . G 7 HOH 303 5308 303 HOH HOH A . G 7 HOH 304 5309 304 HOH HOH A . G 7 HOH 305 5310 305 HOH HOH A . G 7 HOH 306 5311 306 HOH HOH A . G 7 HOH 307 5312 307 HOH HOH A . G 7 HOH 308 5313 308 HOH HOH A . G 7 HOH 309 5314 309 HOH HOH A . G 7 HOH 310 5315 310 HOH HOH A . G 7 HOH 311 5316 311 HOH HOH A . G 7 HOH 312 5317 312 HOH HOH A . G 7 HOH 313 5318 313 HOH HOH A . G 7 HOH 314 5319 314 HOH HOH A . G 7 HOH 315 5320 315 HOH HOH A . G 7 HOH 316 5321 316 HOH HOH A . G 7 HOH 317 5322 317 HOH HOH A . G 7 HOH 318 5323 318 HOH HOH A . G 7 HOH 319 5324 319 HOH HOH A . G 7 HOH 320 5325 320 HOH HOH A . G 7 HOH 321 5326 321 HOH HOH A . G 7 HOH 322 5327 322 HOH HOH A . G 7 HOH 323 5328 323 HOH HOH A . G 7 HOH 324 5329 324 HOH HOH A . G 7 HOH 325 5330 325 HOH HOH A . G 7 HOH 326 5331 326 HOH HOH A . G 7 HOH 327 5332 327 HOH HOH A . G 7 HOH 328 5333 328 HOH HOH A . G 7 HOH 329 5334 329 HOH HOH A . G 7 HOH 330 5335 330 HOH HOH A . G 7 HOH 331 5336 331 HOH HOH A . G 7 HOH 332 5337 332 HOH HOH A . G 7 HOH 333 5338 333 HOH HOH A . G 7 HOH 334 5339 334 HOH HOH A . G 7 HOH 335 5340 335 HOH HOH A . G 7 HOH 336 5341 336 HOH HOH A . G 7 HOH 337 5342 337 HOH HOH A . G 7 HOH 338 5343 338 HOH HOH A . G 7 HOH 339 5344 339 HOH HOH A . G 7 HOH 340 5345 340 HOH HOH A . G 7 HOH 341 5346 341 HOH HOH A . G 7 HOH 342 5347 342 HOH HOH A . G 7 HOH 343 5348 343 HOH HOH A . G 7 HOH 344 5349 344 HOH HOH A . G 7 HOH 345 5350 345 HOH HOH A . G 7 HOH 346 5351 346 HOH HOH A . G 7 HOH 347 5352 347 HOH HOH A . G 7 HOH 348 5353 348 HOH HOH A . G 7 HOH 349 5354 349 HOH HOH A . G 7 HOH 350 5355 350 HOH HOH A . G 7 HOH 351 5356 351 HOH HOH A . G 7 HOH 352 5357 352 HOH HOH A . G 7 HOH 353 5358 353 HOH HOH A . G 7 HOH 354 5359 354 HOH HOH A . G 7 HOH 355 5360 355 HOH HOH A . G 7 HOH 356 5361 356 HOH HOH A . G 7 HOH 357 5362 357 HOH HOH A . G 7 HOH 358 5363 358 HOH HOH A . G 7 HOH 359 5364 359 HOH HOH A . G 7 HOH 360 5365 360 HOH HOH A . G 7 HOH 361 5366 361 HOH HOH A . G 7 HOH 362 5367 362 HOH HOH A . G 7 HOH 363 5368 363 HOH HOH A . G 7 HOH 364 5369 364 HOH HOH A . G 7 HOH 365 5370 365 HOH HOH A . G 7 HOH 366 5371 366 HOH HOH A . G 7 HOH 367 5372 367 HOH HOH A . G 7 HOH 368 5373 368 HOH HOH A . G 7 HOH 369 5374 369 HOH HOH A . G 7 HOH 370 5375 370 HOH HOH A . G 7 HOH 371 5376 371 HOH HOH A . G 7 HOH 372 5377 372 HOH HOH A . G 7 HOH 373 5378 373 HOH HOH A . G 7 HOH 374 5379 374 HOH HOH A . G 7 HOH 375 5380 375 HOH HOH A . G 7 HOH 376 5381 376 HOH HOH A . G 7 HOH 377 5382 377 HOH HOH A . G 7 HOH 378 5383 378 HOH HOH A . G 7 HOH 379 5384 379 HOH HOH A . G 7 HOH 380 5385 380 HOH HOH A . G 7 HOH 381 5386 381 HOH HOH A . G 7 HOH 382 5387 382 HOH HOH A . G 7 HOH 383 5388 383 HOH HOH A . G 7 HOH 384 5389 384 HOH HOH A . G 7 HOH 385 5390 385 HOH HOH A . G 7 HOH 386 5391 386 HOH HOH A . G 7 HOH 387 5392 387 HOH HOH A . G 7 HOH 388 5393 388 HOH HOH A . G 7 HOH 389 5394 389 HOH HOH A . G 7 HOH 390 5395 390 HOH HOH A . G 7 HOH 391 5396 391 HOH HOH A . G 7 HOH 392 5397 392 HOH HOH A . G 7 HOH 393 5398 393 HOH HOH A . G 7 HOH 394 5399 394 HOH HOH A . G 7 HOH 395 5400 395 HOH HOH A . G 7 HOH 396 5401 396 HOH HOH A . G 7 HOH 397 5402 397 HOH HOH A . G 7 HOH 398 5403 398 HOH HOH A . G 7 HOH 399 5404 399 HOH HOH A . G 7 HOH 400 5405 400 HOH HOH A . G 7 HOH 401 5406 401 HOH HOH A . G 7 HOH 402 5407 402 HOH HOH A . G 7 HOH 403 5408 403 HOH HOH A . G 7 HOH 404 5409 404 HOH HOH A . G 7 HOH 405 5410 405 HOH HOH A . G 7 HOH 406 5411 406 HOH HOH A . G 7 HOH 407 5412 407 HOH HOH A . G 7 HOH 408 5413 408 HOH HOH A . G 7 HOH 409 5414 409 HOH HOH A . G 7 HOH 410 5415 410 HOH HOH A . G 7 HOH 411 5416 411 HOH HOH A . G 7 HOH 412 5417 412 HOH HOH A . G 7 HOH 413 5418 413 HOH HOH A . G 7 HOH 414 5419 414 HOH HOH A . G 7 HOH 415 5420 415 HOH HOH A . G 7 HOH 416 5421 416 HOH HOH A . G 7 HOH 417 5422 417 HOH HOH A . G 7 HOH 418 5423 418 HOH HOH A . G 7 HOH 419 5424 419 HOH HOH A . G 7 HOH 420 5425 420 HOH HOH A . G 7 HOH 421 5426 421 HOH HOH A . G 7 HOH 422 5427 422 HOH HOH A . G 7 HOH 423 5428 423 HOH HOH A . G 7 HOH 424 5429 424 HOH HOH A . G 7 HOH 425 5430 425 HOH HOH A . G 7 HOH 426 5431 426 HOH HOH A . G 7 HOH 427 5432 427 HOH HOH A . G 7 HOH 428 5433 428 HOH HOH A . G 7 HOH 429 5434 429 HOH HOH A . G 7 HOH 430 5435 430 HOH HOH A . G 7 HOH 431 5436 431 HOH HOH A . G 7 HOH 432 5437 432 HOH HOH A . G 7 HOH 433 5438 433 HOH HOH A . G 7 HOH 434 5439 434 HOH HOH A . G 7 HOH 435 5440 435 HOH HOH A . G 7 HOH 436 5441 436 HOH HOH A . G 7 HOH 437 5442 437 HOH HOH A . G 7 HOH 438 5443 438 HOH HOH A . G 7 HOH 439 5444 439 HOH HOH A . G 7 HOH 440 5445 440 HOH HOH A . G 7 HOH 441 5446 441 HOH HOH A . G 7 HOH 442 5447 442 HOH HOH A . G 7 HOH 443 5448 443 HOH HOH A . G 7 HOH 444 5449 444 HOH HOH A . G 7 HOH 445 5450 445 HOH HOH A . G 7 HOH 446 5451 446 HOH HOH A . G 7 HOH 447 5452 447 HOH HOH A . G 7 HOH 448 5453 448 HOH HOH A . G 7 HOH 449 5454 449 HOH HOH A . G 7 HOH 450 5455 450 HOH HOH A . G 7 HOH 451 5456 451 HOH HOH A . G 7 HOH 452 5457 452 HOH HOH A . G 7 HOH 453 5458 453 HOH HOH A . G 7 HOH 454 5459 454 HOH HOH A . G 7 HOH 455 5460 455 HOH HOH A . G 7 HOH 456 5461 456 HOH HOH A . G 7 HOH 457 5462 457 HOH HOH A . G 7 HOH 458 5463 458 HOH HOH A . G 7 HOH 459 5464 459 HOH HOH A . G 7 HOH 460 5465 460 HOH HOH A . G 7 HOH 461 5466 461 HOH HOH A . G 7 HOH 462 5467 462 HOH HOH A . G 7 HOH 463 5468 463 HOH HOH A . G 7 HOH 464 5469 464 HOH HOH A . G 7 HOH 465 5470 465 HOH HOH A . G 7 HOH 466 5471 466 HOH HOH A . G 7 HOH 467 5472 467 HOH HOH A . G 7 HOH 468 5473 468 HOH HOH A . G 7 HOH 469 5474 469 HOH HOH A . G 7 HOH 470 5475 470 HOH HOH A . G 7 HOH 471 5476 471 HOH HOH A . G 7 HOH 472 5477 472 HOH HOH A . G 7 HOH 473 5478 473 HOH HOH A . G 7 HOH 474 5479 474 HOH HOH A . G 7 HOH 475 5480 475 HOH HOH A . G 7 HOH 476 5481 476 HOH HOH A . G 7 HOH 477 5482 477 HOH HOH A . G 7 HOH 478 5483 478 HOH HOH A . G 7 HOH 479 5484 479 HOH HOH A . G 7 HOH 480 5485 480 HOH HOH A . G 7 HOH 481 5486 481 HOH HOH A . G 7 HOH 482 5487 482 HOH HOH A . G 7 HOH 483 5488 483 HOH HOH A . G 7 HOH 484 5489 484 HOH HOH A . G 7 HOH 485 5490 485 HOH HOH A . G 7 HOH 486 5491 486 HOH HOH A . G 7 HOH 487 5492 487 HOH HOH A . G 7 HOH 488 5493 488 HOH HOH A . G 7 HOH 489 5494 489 HOH HOH A . G 7 HOH 490 5495 490 HOH HOH A . G 7 HOH 491 5496 491 HOH HOH A . G 7 HOH 492 5497 492 HOH HOH A . G 7 HOH 493 5498 493 HOH HOH A . G 7 HOH 494 5499 494 HOH HOH A . G 7 HOH 495 5500 495 HOH HOH A . G 7 HOH 496 5501 496 HOH HOH A . G 7 HOH 497 5502 497 HOH HOH A . G 7 HOH 498 5503 498 HOH HOH A . G 7 HOH 499 5504 499 HOH HOH A . G 7 HOH 500 5505 500 HOH HOH A . G 7 HOH 501 5506 501 HOH HOH A . G 7 HOH 502 5507 502 HOH HOH A . G 7 HOH 503 5508 503 HOH HOH A . G 7 HOH 504 5509 504 HOH HOH A . G 7 HOH 505 5510 505 HOH HOH A . G 7 HOH 506 5511 506 HOH HOH A . G 7 HOH 507 5512 507 HOH HOH A . G 7 HOH 508 5513 508 HOH HOH A . G 7 HOH 509 5514 509 HOH HOH A . G 7 HOH 510 5515 510 HOH HOH A . G 7 HOH 511 5516 511 HOH HOH A . G 7 HOH 512 5517 512 HOH HOH A . G 7 HOH 513 5518 513 HOH HOH A . G 7 HOH 514 5519 514 HOH HOH A . G 7 HOH 515 5520 515 HOH HOH A . G 7 HOH 516 5521 516 HOH HOH A . G 7 HOH 517 5522 517 HOH HOH A . G 7 HOH 518 5523 518 HOH HOH A . G 7 HOH 519 5524 519 HOH HOH A . G 7 HOH 520 5525 520 HOH HOH A . G 7 HOH 521 5526 521 HOH HOH A . G 7 HOH 522 5527 522 HOH HOH A . G 7 HOH 523 5528 523 HOH HOH A . G 7 HOH 524 5529 524 HOH HOH A . G 7 HOH 525 5530 525 HOH HOH A . G 7 HOH 526 5531 526 HOH HOH A . G 7 HOH 527 5532 527 HOH HOH A . G 7 HOH 528 5533 528 HOH HOH A . G 7 HOH 529 5534 529 HOH HOH A . G 7 HOH 530 5535 530 HOH HOH A . G 7 HOH 531 5536 531 HOH HOH A . G 7 HOH 532 5537 532 HOH HOH A . G 7 HOH 533 5538 533 HOH HOH A . G 7 HOH 534 5539 534 HOH HOH A . G 7 HOH 535 5540 535 HOH HOH A . G 7 HOH 536 5541 536 HOH HOH A . G 7 HOH 537 5542 537 HOH HOH A . G 7 HOH 538 5543 538 HOH HOH A . G 7 HOH 539 5544 539 HOH HOH A . G 7 HOH 540 5545 540 HOH HOH A . G 7 HOH 541 5546 541 HOH HOH A . G 7 HOH 542 5547 542 HOH HOH A . G 7 HOH 543 5548 543 HOH HOH A . G 7 HOH 544 5549 544 HOH HOH A . G 7 HOH 545 5550 545 HOH HOH A . G 7 HOH 546 5551 546 HOH HOH A . G 7 HOH 547 5552 547 HOH HOH A . G 7 HOH 548 5553 548 HOH HOH A . G 7 HOH 549 5554 549 HOH HOH A . G 7 HOH 550 5555 550 HOH HOH A . G 7 HOH 551 5556 551 HOH HOH A . G 7 HOH 552 5557 552 HOH HOH A . G 7 HOH 553 5558 553 HOH HOH A . G 7 HOH 554 5559 554 HOH HOH A . G 7 HOH 555 5560 555 HOH HOH A . G 7 HOH 556 5561 556 HOH HOH A . G 7 HOH 557 5562 557 HOH HOH A . G 7 HOH 558 5563 558 HOH HOH A . G 7 HOH 559 5564 559 HOH HOH A . G 7 HOH 560 5565 560 HOH HOH A . G 7 HOH 561 5566 561 HOH HOH A . G 7 HOH 562 5567 562 HOH HOH A . G 7 HOH 563 5568 563 HOH HOH A . G 7 HOH 564 5569 564 HOH HOH A . G 7 HOH 565 5570 565 HOH HOH A . G 7 HOH 566 5571 566 HOH HOH A . G 7 HOH 567 5572 567 HOH HOH A . G 7 HOH 568 5573 568 HOH HOH A . G 7 HOH 569 5574 569 HOH HOH A . G 7 HOH 570 5575 570 HOH HOH A . G 7 HOH 571 5576 571 HOH HOH A . G 7 HOH 572 5577 572 HOH HOH A . G 7 HOH 573 5578 573 HOH HOH A . G 7 HOH 574 5579 574 HOH HOH A . G 7 HOH 575 5580 575 HOH HOH A . G 7 HOH 576 5581 576 HOH HOH A . G 7 HOH 577 5582 577 HOH HOH A . G 7 HOH 578 5583 578 HOH HOH A . G 7 HOH 579 5584 579 HOH HOH A . G 7 HOH 580 5585 580 HOH HOH A . G 7 HOH 581 5586 581 HOH HOH A . G 7 HOH 582 5587 582 HOH HOH A . G 7 HOH 583 5588 583 HOH HOH A . G 7 HOH 584 5589 584 HOH HOH A . G 7 HOH 585 5590 585 HOH HOH A . G 7 HOH 586 5591 586 HOH HOH A . G 7 HOH 587 5592 587 HOH HOH A . G 7 HOH 588 5593 588 HOH HOH A . G 7 HOH 589 5594 589 HOH HOH A . G 7 HOH 590 5595 590 HOH HOH A . G 7 HOH 591 5596 591 HOH HOH A . G 7 HOH 592 5597 592 HOH HOH A . G 7 HOH 593 5598 593 HOH HOH A . G 7 HOH 594 5599 594 HOH HOH A . G 7 HOH 595 5600 595 HOH HOH A . G 7 HOH 596 5601 596 HOH HOH A . G 7 HOH 597 5602 597 HOH HOH A . G 7 HOH 598 5603 598 HOH HOH A . G 7 HOH 599 5604 599 HOH HOH A . G 7 HOH 600 5605 600 HOH HOH A . G 7 HOH 601 5606 601 HOH HOH A . G 7 HOH 602 5607 602 HOH HOH A . G 7 HOH 603 5608 603 HOH HOH A . G 7 HOH 604 5609 604 HOH HOH A . G 7 HOH 605 5610 605 HOH HOH A . G 7 HOH 606 5611 606 HOH HOH A . G 7 HOH 607 5612 607 HOH HOH A . G 7 HOH 608 5613 608 HOH HOH A . G 7 HOH 609 5614 609 HOH HOH A . G 7 HOH 610 5615 610 HOH HOH A . G 7 HOH 611 5616 611 HOH HOH A . G 7 HOH 612 5617 612 HOH HOH A . G 7 HOH 613 5618 613 HOH HOH A . G 7 HOH 614 5619 614 HOH HOH A . G 7 HOH 615 5620 615 HOH HOH A . G 7 HOH 616 5621 616 HOH HOH A . G 7 HOH 617 5622 617 HOH HOH A . G 7 HOH 618 5623 618 HOH HOH A . G 7 HOH 619 5624 619 HOH HOH A . G 7 HOH 620 5625 620 HOH HOH A . G 7 HOH 621 5626 621 HOH HOH A . G 7 HOH 622 5627 622 HOH HOH A . G 7 HOH 623 5628 623 HOH HOH A . G 7 HOH 624 5629 624 HOH HOH A . G 7 HOH 625 5630 625 HOH HOH A . G 7 HOH 626 5631 626 HOH HOH A . G 7 HOH 627 5632 627 HOH HOH A . G 7 HOH 628 5633 628 HOH HOH A . G 7 HOH 629 5634 629 HOH HOH A . G 7 HOH 630 5635 630 HOH HOH A . G 7 HOH 631 5636 631 HOH HOH A . G 7 HOH 632 5637 632 HOH HOH A . G 7 HOH 633 5638 633 HOH HOH A . G 7 HOH 634 5639 634 HOH HOH A . G 7 HOH 635 5640 635 HOH HOH A . G 7 HOH 636 5641 636 HOH HOH A . G 7 HOH 637 5642 637 HOH HOH A . G 7 HOH 638 5643 638 HOH HOH A . G 7 HOH 639 5644 639 HOH HOH A . G 7 HOH 640 5645 640 HOH HOH A . G 7 HOH 641 5646 641 HOH HOH A . G 7 HOH 642 5647 642 HOH HOH A . G 7 HOH 643 5648 643 HOH HOH A . G 7 HOH 644 5649 644 HOH HOH A . G 7 HOH 645 5650 645 HOH HOH A . G 7 HOH 646 5651 646 HOH HOH A . G 7 HOH 647 5652 647 HOH HOH A . G 7 HOH 648 5653 648 HOH HOH A . G 7 HOH 649 5654 649 HOH HOH A . G 7 HOH 650 5655 650 HOH HOH A . G 7 HOH 651 5656 651 HOH HOH A . G 7 HOH 652 5657 652 HOH HOH A . G 7 HOH 653 5658 653 HOH HOH A . G 7 HOH 654 5659 654 HOH HOH A . G 7 HOH 655 5660 655 HOH HOH A . G 7 HOH 656 5661 656 HOH HOH A . G 7 HOH 657 5662 657 HOH HOH A . G 7 HOH 658 5663 658 HOH HOH A . G 7 HOH 659 5664 659 HOH HOH A . G 7 HOH 660 5665 660 HOH HOH A . G 7 HOH 661 5666 661 HOH HOH A . G 7 HOH 662 5667 662 HOH HOH A . G 7 HOH 663 5668 663 HOH HOH A . G 7 HOH 664 5669 664 HOH HOH A . G 7 HOH 665 5670 665 HOH HOH A . G 7 HOH 666 5671 666 HOH HOH A . G 7 HOH 667 5672 667 HOH HOH A . G 7 HOH 668 5673 668 HOH HOH A . G 7 HOH 669 5674 669 HOH HOH A . G 7 HOH 670 5675 670 HOH HOH A . G 7 HOH 671 5676 671 HOH HOH A . G 7 HOH 672 5677 672 HOH HOH A . G 7 HOH 673 5678 673 HOH HOH A . G 7 HOH 674 5679 674 HOH HOH A . G 7 HOH 675 5680 675 HOH HOH A . G 7 HOH 676 5681 676 HOH HOH A . G 7 HOH 677 5682 677 HOH HOH A . G 7 HOH 678 5683 678 HOH HOH A . G 7 HOH 679 5684 679 HOH HOH A . G 7 HOH 680 5685 680 HOH HOH A . G 7 HOH 681 5686 681 HOH HOH A . G 7 HOH 682 5687 682 HOH HOH A . G 7 HOH 683 5688 683 HOH HOH A . G 7 HOH 684 5689 684 HOH HOH A . G 7 HOH 685 5690 685 HOH HOH A . G 7 HOH 686 5691 686 HOH HOH A . G 7 HOH 687 5692 687 HOH HOH A . G 7 HOH 688 5693 688 HOH HOH A . G 7 HOH 689 5694 689 HOH HOH A . G 7 HOH 690 5695 690 HOH HOH A . G 7 HOH 691 5696 691 HOH HOH A . G 7 HOH 692 5697 692 HOH HOH A . G 7 HOH 693 5698 693 HOH HOH A . G 7 HOH 694 5699 694 HOH HOH A . G 7 HOH 695 5700 695 HOH HOH A . G 7 HOH 696 5701 696 HOH HOH A . G 7 HOH 697 5702 697 HOH HOH A . G 7 HOH 698 5703 698 HOH HOH A . G 7 HOH 699 5704 699 HOH HOH A . G 7 HOH 700 5705 700 HOH HOH A . G 7 HOH 701 5706 701 HOH HOH A . G 7 HOH 702 5707 702 HOH HOH A . G 7 HOH 703 5708 703 HOH HOH A . G 7 HOH 704 5709 704 HOH HOH A . G 7 HOH 705 5710 705 HOH HOH A . G 7 HOH 706 5711 706 HOH HOH A . G 7 HOH 707 5712 707 HOH HOH A . G 7 HOH 708 5713 708 HOH HOH A . G 7 HOH 709 5714 709 HOH HOH A . G 7 HOH 710 5715 710 HOH HOH A . G 7 HOH 711 5716 711 HOH HOH A . G 7 HOH 712 5717 712 HOH HOH A . G 7 HOH 713 5718 713 HOH HOH A . G 7 HOH 714 5719 714 HOH HOH A . G 7 HOH 715 5720 715 HOH HOH A . G 7 HOH 716 5721 716 HOH HOH A . G 7 HOH 717 5722 717 HOH HOH A . G 7 HOH 718 5723 718 HOH HOH A . G 7 HOH 719 5724 719 HOH HOH A . G 7 HOH 720 5725 720 HOH HOH A . G 7 HOH 721 5726 721 HOH HOH A . G 7 HOH 722 5727 722 HOH HOH A . G 7 HOH 723 5728 723 HOH HOH A . G 7 HOH 724 5729 724 HOH HOH A . G 7 HOH 725 5730 725 HOH HOH A . G 7 HOH 726 5731 726 HOH HOH A . G 7 HOH 727 5732 727 HOH HOH A . G 7 HOH 728 5733 728 HOH HOH A . G 7 HOH 729 5734 729 HOH HOH A . G 7 HOH 730 5735 730 HOH HOH A . G 7 HOH 731 5736 731 HOH HOH A . G 7 HOH 732 5737 732 HOH HOH A . G 7 HOH 733 5738 733 HOH HOH A . G 7 HOH 734 5739 734 HOH HOH A . G 7 HOH 735 5740 735 HOH HOH A . G 7 HOH 736 5741 736 HOH HOH A . G 7 HOH 737 5742 737 HOH HOH A . G 7 HOH 738 5743 738 HOH HOH A . G 7 HOH 739 5744 739 HOH HOH A . G 7 HOH 740 5745 740 HOH HOH A . G 7 HOH 741 5746 741 HOH HOH A . G 7 HOH 742 5747 742 HOH HOH A . G 7 HOH 743 5748 743 HOH HOH A . G 7 HOH 744 5749 744 HOH HOH A . G 7 HOH 745 5750 745 HOH HOH A . G 7 HOH 746 5751 746 HOH HOH A . G 7 HOH 747 5752 747 HOH HOH A . G 7 HOH 748 5753 748 HOH HOH A . G 7 HOH 749 5754 749 HOH HOH A . G 7 HOH 750 5755 750 HOH HOH A . G 7 HOH 751 5756 751 HOH HOH A . G 7 HOH 752 5757 752 HOH HOH A . G 7 HOH 753 5758 753 HOH HOH A . G 7 HOH 754 5759 754 HOH HOH A . G 7 HOH 755 5760 755 HOH HOH A . G 7 HOH 756 5761 756 HOH HOH A . G 7 HOH 757 5762 757 HOH HOH A . G 7 HOH 758 5763 758 HOH HOH A . G 7 HOH 759 5764 759 HOH HOH A . G 7 HOH 760 5765 760 HOH HOH A . G 7 HOH 761 5766 761 HOH HOH A . G 7 HOH 762 5767 762 HOH HOH A . G 7 HOH 763 5768 763 HOH HOH A . G 7 HOH 764 5769 764 HOH HOH A . G 7 HOH 765 5770 765 HOH HOH A . G 7 HOH 766 5771 766 HOH HOH A . G 7 HOH 767 5772 767 HOH HOH A . G 7 HOH 768 5773 768 HOH HOH A . G 7 HOH 769 5774 769 HOH HOH A . G 7 HOH 770 5775 770 HOH HOH A . G 7 HOH 771 5776 771 HOH HOH A . G 7 HOH 772 5777 772 HOH HOH A . G 7 HOH 773 5778 773 HOH HOH A . G 7 HOH 774 5779 774 HOH HOH A . G 7 HOH 775 5780 775 HOH HOH A . G 7 HOH 776 5781 776 HOH HOH A . G 7 HOH 777 5782 777 HOH HOH A . G 7 HOH 778 5783 778 HOH HOH A . G 7 HOH 779 5784 779 HOH HOH A . G 7 HOH 780 5785 780 HOH HOH A . G 7 HOH 781 5786 781 HOH HOH A . G 7 HOH 782 5787 782 HOH HOH A . G 7 HOH 783 5788 783 HOH HOH A . G 7 HOH 784 5789 784 HOH HOH A . G 7 HOH 785 5790 785 HOH HOH A . G 7 HOH 786 5791 786 HOH HOH A . G 7 HOH 787 5792 787 HOH HOH A . G 7 HOH 788 5793 788 HOH HOH A . G 7 HOH 789 5794 789 HOH HOH A . G 7 HOH 790 5795 790 HOH HOH A . G 7 HOH 791 5796 791 HOH HOH A . G 7 HOH 792 5797 792 HOH HOH A . G 7 HOH 793 5798 793 HOH HOH A . G 7 HOH 794 5799 794 HOH HOH A . G 7 HOH 795 5800 795 HOH HOH A . G 7 HOH 796 5801 796 HOH HOH A . G 7 HOH 797 5802 797 HOH HOH A . G 7 HOH 798 5803 798 HOH HOH A . G 7 HOH 799 5804 799 HOH HOH A . G 7 HOH 800 5805 800 HOH HOH A . G 7 HOH 801 5806 801 HOH HOH A . G 7 HOH 802 5807 802 HOH HOH A . G 7 HOH 803 5808 803 HOH HOH A . G 7 HOH 804 5809 804 HOH HOH A . G 7 HOH 805 5810 805 HOH HOH A . G 7 HOH 806 5811 806 HOH HOH A . G 7 HOH 807 5812 807 HOH HOH A . G 7 HOH 808 5813 808 HOH HOH A . G 7 HOH 809 5814 809 HOH HOH A . G 7 HOH 810 5815 810 HOH HOH A . G 7 HOH 811 5816 811 HOH HOH A . G 7 HOH 812 5817 812 HOH HOH A . G 7 HOH 813 5818 813 HOH HOH A . G 7 HOH 814 5819 814 HOH HOH A . G 7 HOH 815 5820 815 HOH HOH A . G 7 HOH 816 5821 816 HOH HOH A . G 7 HOH 817 5822 817 HOH HOH A . G 7 HOH 818 5823 818 HOH HOH A . G 7 HOH 819 5824 819 HOH HOH A . G 7 HOH 820 5825 820 HOH HOH A . G 7 HOH 821 5826 821 HOH HOH A . G 7 HOH 822 5827 822 HOH HOH A . G 7 HOH 823 5828 823 HOH HOH A . G 7 HOH 824 5829 824 HOH HOH A . G 7 HOH 825 5830 825 HOH HOH A . G 7 HOH 826 5831 826 HOH HOH A . G 7 HOH 827 5832 827 HOH HOH A . G 7 HOH 828 5833 828 HOH HOH A . G 7 HOH 829 5834 829 HOH HOH A . G 7 HOH 830 5835 830 HOH HOH A . G 7 HOH 831 5836 831 HOH HOH A . G 7 HOH 832 5837 832 HOH HOH A . G 7 HOH 833 5838 833 HOH HOH A . G 7 HOH 834 5839 834 HOH HOH A . G 7 HOH 835 5840 835 HOH HOH A . G 7 HOH 836 5841 836 HOH HOH A . G 7 HOH 837 5842 837 HOH HOH A . G 7 HOH 838 5843 838 HOH HOH A . G 7 HOH 839 5844 839 HOH HOH A . G 7 HOH 840 5845 840 HOH HOH A . G 7 HOH 841 5846 841 HOH HOH A . G 7 HOH 842 5847 842 HOH HOH A . G 7 HOH 843 5848 843 HOH HOH A . G 7 HOH 844 5849 844 HOH HOH A . G 7 HOH 845 5850 845 HOH HOH A . G 7 HOH 846 5851 846 HOH HOH A . G 7 HOH 847 5852 847 HOH HOH A . G 7 HOH 848 5853 848 HOH HOH A . G 7 HOH 849 5854 849 HOH HOH A . G 7 HOH 850 5855 850 HOH HOH A . G 7 HOH 851 5856 851 HOH HOH A . G 7 HOH 852 5857 852 HOH HOH A . G 7 HOH 853 5858 853 HOH HOH A . G 7 HOH 854 5859 854 HOH HOH A . G 7 HOH 855 5860 855 HOH HOH A . G 7 HOH 856 5861 856 HOH HOH A . G 7 HOH 857 5862 857 HOH HOH A . G 7 HOH 858 5863 858 HOH HOH A . G 7 HOH 859 5864 859 HOH HOH A . G 7 HOH 860 5865 860 HOH HOH A . G 7 HOH 861 5866 861 HOH HOH A . G 7 HOH 862 5867 862 HOH HOH A . G 7 HOH 863 5868 863 HOH HOH A . G 7 HOH 864 5869 864 HOH HOH A . G 7 HOH 865 5870 865 HOH HOH A . G 7 HOH 866 5871 866 HOH HOH A . G 7 HOH 867 5872 867 HOH HOH A . G 7 HOH 868 5873 868 HOH HOH A . G 7 HOH 869 5874 869 HOH HOH A . G 7 HOH 870 5875 870 HOH HOH A . G 7 HOH 871 5876 871 HOH HOH A . G 7 HOH 872 5877 872 HOH HOH A . G 7 HOH 873 5878 873 HOH HOH A . G 7 HOH 874 5879 874 HOH HOH A . G 7 HOH 875 5880 875 HOH HOH A . G 7 HOH 876 5881 876 HOH HOH A . G 7 HOH 877 5882 877 HOH HOH A . G 7 HOH 878 5883 878 HOH HOH A . G 7 HOH 879 5884 879 HOH HOH A . G 7 HOH 880 5885 880 HOH HOH A . G 7 HOH 881 5886 881 HOH HOH A . G 7 HOH 882 5887 882 HOH HOH A . G 7 HOH 883 5888 883 HOH HOH A . G 7 HOH 884 5889 884 HOH HOH A . G 7 HOH 885 5890 885 HOH HOH A . G 7 HOH 886 5891 886 HOH HOH A . G 7 HOH 887 5892 887 HOH HOH A . G 7 HOH 888 5893 888 HOH HOH A . G 7 HOH 889 5894 889 HOH HOH A . G 7 HOH 890 5895 890 HOH HOH A . G 7 HOH 891 5896 891 HOH HOH A . G 7 HOH 892 5897 892 HOH HOH A . G 7 HOH 893 5898 893 HOH HOH A . G 7 HOH 894 5899 894 HOH HOH A . G 7 HOH 895 5900 895 HOH HOH A . G 7 HOH 896 5901 896 HOH HOH A . G 7 HOH 897 5902 897 HOH HOH A . G 7 HOH 898 5903 898 HOH HOH A . G 7 HOH 899 5904 899 HOH HOH A . G 7 HOH 900 5905 900 HOH HOH A . G 7 HOH 901 5906 901 HOH HOH A . G 7 HOH 902 5907 902 HOH HOH A . G 7 HOH 903 5908 903 HOH HOH A . G 7 HOH 904 5909 904 HOH HOH A . G 7 HOH 905 5910 905 HOH HOH A . G 7 HOH 906 5911 906 HOH HOH A . G 7 HOH 907 5912 907 HOH HOH A . G 7 HOH 908 5913 908 HOH HOH A . G 7 HOH 909 5914 909 HOH HOH A . G 7 HOH 910 5915 910 HOH HOH A . G 7 HOH 911 5916 911 HOH HOH A . G 7 HOH 912 5917 912 HOH HOH A . G 7 HOH 913 5918 913 HOH HOH A . G 7 HOH 914 5919 914 HOH HOH A . G 7 HOH 915 5920 915 HOH HOH A . G 7 HOH 916 5921 916 HOH HOH A . G 7 HOH 917 5922 917 HOH HOH A . G 7 HOH 918 5923 918 HOH HOH A . G 7 HOH 919 5924 919 HOH HOH A . G 7 HOH 920 5925 920 HOH HOH A . G 7 HOH 921 5926 921 HOH HOH A . G 7 HOH 922 5927 922 HOH HOH A . G 7 HOH 923 5928 923 HOH HOH A . G 7 HOH 924 5929 924 HOH HOH A . G 7 HOH 925 5930 925 HOH HOH A . G 7 HOH 926 5931 926 HOH HOH A . G 7 HOH 927 5932 927 HOH HOH A . G 7 HOH 928 5933 928 HOH HOH A . G 7 HOH 929 5934 929 HOH HOH A . G 7 HOH 930 5935 930 HOH HOH A . G 7 HOH 931 5936 931 HOH HOH A . G 7 HOH 932 5937 932 HOH HOH A . G 7 HOH 933 5938 933 HOH HOH A . G 7 HOH 934 5939 934 HOH HOH A . G 7 HOH 935 5940 935 HOH HOH A . G 7 HOH 936 5941 936 HOH HOH A . G 7 HOH 937 5942 937 HOH HOH A . G 7 HOH 938 5943 938 HOH HOH A . G 7 HOH 939 5944 939 HOH HOH A . G 7 HOH 940 5945 940 HOH HOH A . G 7 HOH 941 5946 941 HOH HOH A . G 7 HOH 942 5947 942 HOH HOH A . G 7 HOH 943 5948 943 HOH HOH A . G 7 HOH 944 5949 944 HOH HOH A . G 7 HOH 945 5950 945 HOH HOH A . G 7 HOH 946 5951 946 HOH HOH A . G 7 HOH 947 5952 947 HOH HOH A . G 7 HOH 948 5953 948 HOH HOH A . G 7 HOH 949 5954 949 HOH HOH A . G 7 HOH 950 5955 950 HOH HOH A . G 7 HOH 951 5956 951 HOH HOH A . G 7 HOH 952 5957 952 HOH HOH A . G 7 HOH 953 5958 953 HOH HOH A . G 7 HOH 954 5959 954 HOH HOH A . G 7 HOH 955 5960 955 HOH HOH A . G 7 HOH 956 5961 956 HOH HOH A . G 7 HOH 957 5962 957 HOH HOH A . G 7 HOH 958 5963 958 HOH HOH A . G 7 HOH 959 5964 959 HOH HOH A . G 7 HOH 960 5965 960 HOH HOH A . G 7 HOH 961 5966 961 HOH HOH A . G 7 HOH 962 5967 962 HOH HOH A . G 7 HOH 963 5968 963 HOH HOH A . G 7 HOH 964 5969 964 HOH HOH A . G 7 HOH 965 5970 965 HOH HOH A . G 7 HOH 966 5971 966 HOH HOH A . G 7 HOH 967 5972 967 HOH HOH A . G 7 HOH 968 5973 968 HOH HOH A . G 7 HOH 969 5974 969 HOH HOH A . G 7 HOH 970 5975 970 HOH HOH A . G 7 HOH 971 5976 971 HOH HOH A . G 7 HOH 972 5977 972 HOH HOH A . G 7 HOH 973 5978 973 HOH HOH A . G 7 HOH 974 5979 974 HOH HOH A . G 7 HOH 975 5980 975 HOH HOH A . G 7 HOH 976 5981 976 HOH HOH A . G 7 HOH 977 5982 977 HOH HOH A . G 7 HOH 978 5983 978 HOH HOH A . G 7 HOH 979 5984 979 HOH HOH A . G 7 HOH 980 5985 980 HOH HOH A . G 7 HOH 981 5986 981 HOH HOH A . G 7 HOH 982 5987 982 HOH HOH A . G 7 HOH 983 5988 983 HOH HOH A . G 7 HOH 984 5989 984 HOH HOH A . G 7 HOH 985 5990 985 HOH HOH A . G 7 HOH 986 5991 986 HOH HOH A . G 7 HOH 987 5992 987 HOH HOH A . G 7 HOH 988 5993 988 HOH HOH A . G 7 HOH 989 5994 989 HOH HOH A . G 7 HOH 990 5995 990 HOH HOH A . G 7 HOH 991 5996 991 HOH HOH A . G 7 HOH 992 5997 992 HOH HOH A . G 7 HOH 993 5998 993 HOH HOH A . G 7 HOH 994 5999 994 HOH HOH A . G 7 HOH 995 6000 995 HOH HOH A . G 7 HOH 996 6001 996 HOH HOH A . G 7 HOH 997 6002 997 HOH HOH A . G 7 HOH 998 6003 998 HOH HOH A . G 7 HOH 999 6004 999 HOH HOH A . G 7 HOH 1000 6005 1000 HOH HOH A . G 7 HOH 1001 6006 1001 HOH HOH A . G 7 HOH 1002 6007 1002 HOH HOH A . G 7 HOH 1003 6008 1003 HOH HOH A . G 7 HOH 1004 6009 1004 HOH HOH A . G 7 HOH 1005 6010 1005 HOH HOH A . G 7 HOH 1006 6011 1006 HOH HOH A . G 7 HOH 1007 6012 1007 HOH HOH A . G 7 HOH 1008 6013 1008 HOH HOH A . G 7 HOH 1009 6014 1009 HOH HOH A . G 7 HOH 1010 6015 1010 HOH HOH A . G 7 HOH 1011 6016 1011 HOH HOH A . G 7 HOH 1012 6017 1012 HOH HOH A . G 7 HOH 1013 6018 1013 HOH HOH A . G 7 HOH 1014 6019 1014 HOH HOH A . G 7 HOH 1015 6020 1015 HOH HOH A . G 7 HOH 1016 6021 1016 HOH HOH A . G 7 HOH 1017 6022 1017 HOH HOH A . G 7 HOH 1018 6023 1018 HOH HOH A . G 7 HOH 1019 6024 1019 HOH HOH A . G 7 HOH 1020 6025 1020 HOH HOH A . G 7 HOH 1021 6026 1021 HOH HOH A . G 7 HOH 1022 6027 1022 HOH HOH A . G 7 HOH 1023 6028 1023 HOH HOH A . G 7 HOH 1024 6029 1024 HOH HOH A . G 7 HOH 1025 6030 1025 HOH HOH A . G 7 HOH 1026 6031 1026 HOH HOH A . G 7 HOH 1027 6032 1027 HOH HOH A . G 7 HOH 1028 6033 1028 HOH HOH A . G 7 HOH 1029 6034 1029 HOH HOH A . G 7 HOH 1030 6035 1030 HOH HOH A . G 7 HOH 1031 6036 1031 HOH HOH A . G 7 HOH 1032 6037 1032 HOH HOH A . G 7 HOH 1033 6038 1033 HOH HOH A . G 7 HOH 1034 6039 1034 HOH HOH A . G 7 HOH 1035 6040 1035 HOH HOH A . G 7 HOH 1036 6041 1036 HOH HOH A . G 7 HOH 1037 6042 1037 HOH HOH A . G 7 HOH 1038 6043 1038 HOH HOH A . G 7 HOH 1039 6044 1039 HOH HOH A . G 7 HOH 1040 6045 1040 HOH HOH A . G 7 HOH 1041 6046 1041 HOH HOH A . G 7 HOH 1042 6047 1042 HOH HOH A . G 7 HOH 1043 6048 1043 HOH HOH A . G 7 HOH 1044 6049 1044 HOH HOH A . G 7 HOH 1045 6050 1045 HOH HOH A . G 7 HOH 1046 6051 1046 HOH HOH A . G 7 HOH 1047 6052 1047 HOH HOH A . G 7 HOH 1048 6053 1048 HOH HOH A . # _pdbx_struct_mod_residue.id 1 _pdbx_struct_mod_residue.label_asym_id A _pdbx_struct_mod_residue.label_comp_id ASN _pdbx_struct_mod_residue.label_seq_id 194 _pdbx_struct_mod_residue.auth_asym_id A _pdbx_struct_mod_residue.auth_comp_id ASN _pdbx_struct_mod_residue.auth_seq_id 194 _pdbx_struct_mod_residue.PDB_ins_code ? _pdbx_struct_mod_residue.parent_comp_id ASN _pdbx_struct_mod_residue.details 'GLYCOSYLATION SITE' # _pdbx_struct_assembly.id 1 _pdbx_struct_assembly.details author_defined_assembly _pdbx_struct_assembly.method_details ? _pdbx_struct_assembly.oligomeric_details monomeric _pdbx_struct_assembly.oligomeric_count 1 # _pdbx_struct_assembly_gen.assembly_id 1 _pdbx_struct_assembly_gen.oper_expression 1 _pdbx_struct_assembly_gen.asym_id_list A,B,C,D,E,F,G # _pdbx_struct_oper_list.id 1 _pdbx_struct_oper_list.type 'identity operation' _pdbx_struct_oper_list.name 1_555 _pdbx_struct_oper_list.symmetry_operation x,y,z _pdbx_struct_oper_list.matrix[1][1] 1.0000000000 _pdbx_struct_oper_list.matrix[1][2] 0.0000000000 _pdbx_struct_oper_list.matrix[1][3] 0.0000000000 _pdbx_struct_oper_list.vector[1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][1] 0.0000000000 _pdbx_struct_oper_list.matrix[2][2] 1.0000000000 _pdbx_struct_oper_list.matrix[2][3] 0.0000000000 _pdbx_struct_oper_list.vector[2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][1] 0.0000000000 _pdbx_struct_oper_list.matrix[3][2] 0.0000000000 _pdbx_struct_oper_list.matrix[3][3] 1.0000000000 _pdbx_struct_oper_list.vector[3] 0.0000000000 # loop_ _pdbx_struct_conn_angle.id _pdbx_struct_conn_angle.ptnr1_label_atom_id _pdbx_struct_conn_angle.ptnr1_label_alt_id _pdbx_struct_conn_angle.ptnr1_label_asym_id _pdbx_struct_conn_angle.ptnr1_label_comp_id _pdbx_struct_conn_angle.ptnr1_label_seq_id _pdbx_struct_conn_angle.ptnr1_auth_atom_id _pdbx_struct_conn_angle.ptnr1_auth_asym_id _pdbx_struct_conn_angle.ptnr1_auth_comp_id _pdbx_struct_conn_angle.ptnr1_auth_seq_id _pdbx_struct_conn_angle.ptnr1_PDB_ins_code _pdbx_struct_conn_angle.ptnr1_symmetry _pdbx_struct_conn_angle.ptnr2_label_atom_id _pdbx_struct_conn_angle.ptnr2_label_alt_id _pdbx_struct_conn_angle.ptnr2_label_asym_id _pdbx_struct_conn_angle.ptnr2_label_comp_id _pdbx_struct_conn_angle.ptnr2_label_seq_id _pdbx_struct_conn_angle.ptnr2_auth_atom_id _pdbx_struct_conn_angle.ptnr2_auth_asym_id _pdbx_struct_conn_angle.ptnr2_auth_comp_id _pdbx_struct_conn_angle.ptnr2_auth_seq_id _pdbx_struct_conn_angle.ptnr2_PDB_ins_code _pdbx_struct_conn_angle.ptnr2_symmetry _pdbx_struct_conn_angle.ptnr3_label_atom_id _pdbx_struct_conn_angle.ptnr3_label_alt_id _pdbx_struct_conn_angle.ptnr3_label_asym_id _pdbx_struct_conn_angle.ptnr3_label_comp_id _pdbx_struct_conn_angle.ptnr3_label_seq_id _pdbx_struct_conn_angle.ptnr3_auth_atom_id _pdbx_struct_conn_angle.ptnr3_auth_asym_id _pdbx_struct_conn_angle.ptnr3_auth_comp_id _pdbx_struct_conn_angle.ptnr3_auth_seq_id _pdbx_struct_conn_angle.ptnr3_PDB_ins_code _pdbx_struct_conn_angle.ptnr3_symmetry _pdbx_struct_conn_angle.value _pdbx_struct_conn_angle.value_esd 1 O3 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 O4 ? E MSN . ? A MSN 5002 ? 1_555 76.5 ? 2 O3 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 92.9 ? 3 O4 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 169.3 ? 4 O3 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 165.9 ? 5 O4 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 89.6 ? 6 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 101.0 ? 7 O3 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 85.0 ? 8 O4 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 86.5 ? 9 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 91.3 ? 10 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 92.2 ? 11 O3 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 86.7 ? 12 O4 ? E MSN . ? A MSN 5002 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 81.9 ? 13 NE2 ? A HIS 471 ? A HIS 471 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 99.0 ? 14 NE2 ? A HIS 90 ? A HIS 90 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 93.5 ? 15 OD1 ? A ASP 92 ? A ASP 92 ? 1_555 ZN ? C ZN . ? A ZN 5001 ? 1_555 OD2 ? A ASP 204 ? A ASP 204 ? 1_555 167.0 ? # loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2006-07-04 2 'Structure model' 1 1 2008-05-01 3 'Structure model' 1 2 2011-07-13 4 'Structure model' 1 3 2017-10-18 # _pdbx_audit_revision_details.ordinal 1 _pdbx_audit_revision_details.revision_ordinal 1 _pdbx_audit_revision_details.data_content_type 'Structure model' _pdbx_audit_revision_details.provider repository _pdbx_audit_revision_details.type 'Initial release' _pdbx_audit_revision_details.description ? # loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 2 'Structure model' 'Version format compliance' 2 3 'Structure model' 'Non-polymer description' 3 3 'Structure model' 'Version format compliance' 4 4 'Structure model' 'Refinement description' # _pdbx_audit_revision_category.ordinal 1 _pdbx_audit_revision_category.revision_ordinal 4 _pdbx_audit_revision_category.data_content_type 'Structure model' _pdbx_audit_revision_category.category software # loop_ _software.name _software.classification _software.version _software.citation_id _software.pdbx_ordinal DENZO 'data reduction' . ? 1 SCALEPACK 'data scaling' . ? 2 CNS refinement . ? 3 CNS phasing . ? 4 # _pdbx_validate_rmsd_bond.id 1 _pdbx_validate_rmsd_bond.PDB_model_num 1 _pdbx_validate_rmsd_bond.auth_atom_id_1 CB _pdbx_validate_rmsd_bond.auth_asym_id_1 A _pdbx_validate_rmsd_bond.auth_comp_id_1 HIS _pdbx_validate_rmsd_bond.auth_seq_id_1 117 _pdbx_validate_rmsd_bond.PDB_ins_code_1 ? _pdbx_validate_rmsd_bond.label_alt_id_1 ? _pdbx_validate_rmsd_bond.auth_atom_id_2 CG _pdbx_validate_rmsd_bond.auth_asym_id_2 A _pdbx_validate_rmsd_bond.auth_comp_id_2 HIS _pdbx_validate_rmsd_bond.auth_seq_id_2 117 _pdbx_validate_rmsd_bond.PDB_ins_code_2 ? _pdbx_validate_rmsd_bond.label_alt_id_2 B _pdbx_validate_rmsd_bond.bond_value 1.374 _pdbx_validate_rmsd_bond.bond_target_value 1.492 _pdbx_validate_rmsd_bond.bond_deviation -0.118 _pdbx_validate_rmsd_bond.bond_standard_deviation 0.016 _pdbx_validate_rmsd_bond.linker_flag N # loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 NE A ARG 540 ? ? CZ A ARG 540 ? ? NH1 A ARG 540 ? ? 123.72 120.30 3.42 0.50 N 2 1 NE A ARG 818 ? ? CZ A ARG 818 ? ? NH2 A ARG 818 ? ? 117.01 120.30 -3.29 0.50 N 3 1 NE A ARG 868 ? ? CZ A ARG 868 ? ? NH1 A ARG 868 ? ? 123.34 120.30 3.04 0.50 N 4 1 NE A ARG 963 ? ? CZ A ARG 963 ? ? NH2 A ARG 963 ? ? 116.80 120.30 -3.50 0.50 N # loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 ASP A 56 ? ? -105.44 74.67 2 1 HIS A 79 ? ? -159.12 84.91 3 1 TRP A 95 ? ? -168.22 -90.06 4 1 ASP A 106 ? ? -130.88 -58.31 5 1 THR A 162 ? ? 65.15 -62.88 6 1 GLN A 227 ? ? -137.22 -45.49 7 1 ASP A 340 ? ? -168.96 -164.40 8 1 LYS A 345 ? ? -90.03 -66.12 9 1 SER A 411 ? ? 36.23 -123.50 10 1 HIS A 471 ? ? -65.27 4.48 11 1 PHE A 519 ? ? -59.29 -5.33 12 1 ILE A 549 ? ? -149.09 -51.96 13 1 LEU A 550 ? ? -164.73 117.19 14 1 PRO A 562 ? ? -81.58 37.51 15 1 PRO A 665 ? ? -59.27 -72.49 16 1 SER A 762 ? ? 74.16 -4.62 17 1 ILE A 831 ? ? -118.83 77.32 18 1 SER A 833 ? ? -147.57 -17.39 19 1 GLU A 991 ? ? 25.92 95.55 20 1 GLU A 992 ? ? -143.73 17.82 21 1 HIS A 993 ? ? -111.96 77.09 # loop_ _pdbx_validate_main_chain_plane.id _pdbx_validate_main_chain_plane.PDB_model_num _pdbx_validate_main_chain_plane.auth_comp_id _pdbx_validate_main_chain_plane.auth_asym_id _pdbx_validate_main_chain_plane.auth_seq_id _pdbx_validate_main_chain_plane.PDB_ins_code _pdbx_validate_main_chain_plane.label_alt_id _pdbx_validate_main_chain_plane.improper_torsion_angle 1 1 SER A 53 ? B 13.46 2 1 LEU A 979 ? B -12.41 # _pdbx_validate_planes.id 1 _pdbx_validate_planes.PDB_model_num 1 _pdbx_validate_planes.auth_comp_id TYR _pdbx_validate_planes.auth_asym_id A _pdbx_validate_planes.auth_seq_id 102 _pdbx_validate_planes.PDB_ins_code ? _pdbx_validate_planes.label_alt_id ? _pdbx_validate_planes.rmsd 0.065 _pdbx_validate_planes.type 'SIDE CHAIN' # _pdbx_validate_chiral.id 1 _pdbx_validate_chiral.PDB_model_num 1 _pdbx_validate_chiral.auth_atom_id C4 _pdbx_validate_chiral.label_alt_id ? _pdbx_validate_chiral.auth_asym_id A _pdbx_validate_chiral.auth_comp_id MPD _pdbx_validate_chiral.auth_seq_id 5003 _pdbx_validate_chiral.PDB_ins_code ? _pdbx_validate_chiral.details 'WRONG HAND' _pdbx_validate_chiral.omega . # loop_ _pdbx_unobs_or_zero_occ_residues.id _pdbx_unobs_or_zero_occ_residues.PDB_model_num _pdbx_unobs_or_zero_occ_residues.polymer_flag _pdbx_unobs_or_zero_occ_residues.occupancy_flag _pdbx_unobs_or_zero_occ_residues.auth_asym_id _pdbx_unobs_or_zero_occ_residues.auth_comp_id _pdbx_unobs_or_zero_occ_residues.auth_seq_id _pdbx_unobs_or_zero_occ_residues.PDB_ins_code _pdbx_unobs_or_zero_occ_residues.label_asym_id _pdbx_unobs_or_zero_occ_residues.label_comp_id _pdbx_unobs_or_zero_occ_residues.label_seq_id 1 1 Y 1 A ARG 1 ? A ARG 1 2 1 Y 1 A SER 2 ? A SER 2 3 1 Y 1 A SER 3 ? A SER 3 4 1 Y 1 A HIS 4 ? A HIS 4 5 1 Y 1 A HIS 5 ? A HIS 5 6 1 Y 1 A HIS 6 ? A HIS 6 7 1 Y 1 A HIS 7 ? A HIS 7 8 1 Y 1 A HIS 8 ? A HIS 8 9 1 Y 1 A HIS 9 ? A HIS 9 10 1 Y 1 A GLY 10 ? A GLY 10 11 1 Y 1 A GLU 11 ? A GLU 11 12 1 Y 1 A PHE 12 ? A PHE 12 13 1 Y 1 A ASP 13 ? A ASP 13 14 1 Y 1 A ASP 14 ? A ASP 14 15 1 Y 1 A PRO 15 ? A PRO 15 16 1 Y 1 A ILE 16 ? A ILE 16 17 1 Y 1 A ARG 17 ? A ARG 17 18 1 Y 1 A PRO 18 ? A PRO 18 19 1 Y 1 A PRO 19 ? A PRO 19 20 1 Y 1 A LEU 20 ? A LEU 20 21 1 Y 1 A LYS 21 ? A LYS 21 22 1 Y 1 A VAL 22 ? A VAL 22 23 1 Y 1 A ALA 23 ? A ALA 23 24 1 Y 1 A ARG 24 ? A ARG 24 25 1 Y 1 A SER 25 ? A SER 25 26 1 Y 1 A PRO 26 ? A PRO 26 27 1 Y 1 A ARG 27 ? A ARG 27 28 1 Y 1 A PRO 28 ? A PRO 28 29 1 Y 1 A GLY 29 ? A GLY 29 30 1 Y 1 A GLN 30 ? A GLN 30 31 1 Y 1 A SER 1045 ? A SER 1045 # loop_ _pdbx_entity_nonpoly.entity_id _pdbx_entity_nonpoly.name _pdbx_entity_nonpoly.comp_id 2 N-ACETYL-D-GLUCOSAMINE NAG 3 'ZINC ION' ZN 4 'PHOSPHATE ION' PO4 5 '(1R,2R,3R,4S,5R)-4-AMINO-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL' MSN 6 '(4S)-2-METHYL-2,4-PENTANEDIOL' MPD 7 water HOH #